bluuebunny/crossref_metadata_2025 huggingface dataset:
Lateral Sinus Thrombosis as a Sequela of Chronic Mastoiditis
Authors: Peng Tee Shao , Othman Nik Adilah Nik , Misron Khairunnisak
Published: June 2024

Lateral sinus thrombosis (LST) is a known but rare complication of chronic otitis media and mastoiditis in the antibiotic era. The classic symptoms of picket fence fever and other unspecific symptoms could be masked by the usage of the antibiotics contributed to the late presentation and delay in treatment. Thus, clinicians should be vigilant and detect this complication early to prevent mortality and morbidity. Administration of broad-spectrum antibiotics and surgical mastoidectomy to eradicate the perisinus infection are the main treatment modalities. Here, we report a case of partially treated chronic otitis media complicated with LST after a 6 months gap of defaulted follow-up.
A Case of Middle Ear Adenomatous Neuroendocrine Tumors: Proposal of a Staging System
Authors: Hyakusoku Hiroshi , Aoyama Jun , Kamoshida Risa , Nakayama Meijin
Published: June 2024

A 49-year-old man visited a local otolaryngology clinic with left hearing loss. He was diagnosed as left middle ear tumor and referred to us. The tumor was protruding from the left tympanic membrane. Computed tomography (CT) revealed thickening of the tympanic membrane, space-occupying lesions in the middle ear cavity and mastoid air cells, and no bone destruction in the left middle ear. Magnetic resonance imaging confirmed the CT findings, and the lesions were hyperintense on T1- and T2-weighted imaging. He was diagnosed as middle ear adenomatous neuroendocrine tumor (MEANT) with a pathological result. The patient underwent postauricular approach and canal wall-down mastoidectomy. The tumor occupied the mastoid air cells and extended into the middle ear mucosa. To prevent perilymphatic fistula, the tumor was excised as extensively as possible, while preserving the tumor around and adjacent to the stapes footplate. MEANT is extremely rare and long-term follow-up is necessary due to be potential for tumor regrowth or recurrence. Herein, we propose a new staging system for MEANT.
Death from Fat Embolism after Lipectomy in a Patient with Madelung’s Disease
Authors: Yang Xing-An , Yang Teng-Fei , Zhang Fu , Kong Jiang-Wei , Meng Zi-Lin , Liao Xin-Biao , Liang Pei-Yu , Li Dong-Ri
Published: June 2024

A 56-year-old man with a long history of alcoholism and a palpable raised mass about 23 cm × 12 cm in size on his neck was diagnosed with Madelung’s disease (MD); the patient also had hyperuricemia. On day 1, he underwent neck lipoma tissue resection and suddenly had dyspnea 9 h after the operation, which was followed by cardiac arrest. After heart rate resuscitation, he developed a heartbeat, but he remained in a coma and died 9 days after the operation. No obvious pathological tracheal compression from a hematoma was observed while evaluating the patient’s neck on autopsy. On microscopy, the patient had an extensive pulmonary fat embolism, partial alveolar septal rupture and hemorrhage, and fat particles, and there was extensive infiltration of macrophages, which had phagocytosed fat particles, in the alveolar cavity. There was also evidence of pulmonary infection and hypoxic-ischemic encephalopathy. The cause of death was postoperative pulmonary fat embolism resulting in pneumonia and central nervous system injury. This is the first report of a patient with MD who died of a fatal pulmonary fat embolism after neck lipoma tissue resection. Medicolegal experts and clinicians should pay sufficient attention to this case.
Identification of Dermal Crease Patterns as a Link between Genetics and Periodontitis: Reliability and Credibility
Authors: Patnaik B. Bharghavi , Penmetsa Gautami S. , Vinnakota Keerthi , Ramaraju Alluri Venkata , Alla Rama Krishna
Published: June 2024

Introduction:

The disruptions in the ectodermal layer during intrauterine growth in the process of the formation of epidermal ridges can be linked to the association between dermatoglyphics and abnormalities of the tooth and periodontium. Given the genetic linkage of periodontal disease this study was hypothesized at observing the association of chronic periodontitis, aggressive periodontitis, and individuals with healthy periodontium as per the 1999 AAP classification of periodontitis with their fingerprint patterns and ridge count.

Materials and Methods:

Patients belonging to an age cohort of 18–50 who visited the department of periodontics and implantology were included in the study. Patients’ periodontal status was determined and was enrolled in the study. A total of 114 subjects were compared, where 38 subjects belonged to the individual group of periodontal condition that are designated as Group A (healthy), Group B (chronic periodontitis), and Group C (aggressive periodontitis). A total of 1140 fingerprints were collected. They were analyzed and classified according to their patterns and also the ridges were counted.

Results:

The comparison between three groups showed a statistically significant difference between increased percentage frequency of radial loops (28%) in chronic periodontitis and plain whorls (26.3%) in aggressive periodontitis. There was a significant difference between ridge count among all the three groups, the highest being in healthy and the least between aggressive periodontal conditions.

Conclusion:

Observations of the study show that there was a difference in fingerprint pattern between patients of all the three periodontal conditions indicating a link between epidermal ridges and condition of periodontium.
Relation between Work Stress and Physical Activity among Physiotherapists
Authors: Mehta Riddhi Yogesh , Oberoi Mugdha
Published: June 2024

Abstract

Background:

Physiotherapists treat patients with a variety of acute and chronic conditions for long periods, and increasing physical demands that may consequently lead to work related stress.

Objectives:

The aim of this study was to examine if there is a relationship between work stress and physical activity in practicing physiotherapists.

Materials and Methods:

This study was a cross-sectional, online survey in which a total of 100 male and female physiotherapists working in various sectors participated. Work stress was measured using the Occupational Stress Index, and physical activity was measured using International Physical Activity Questionnaire–Short Form.

Results:

Overall, a weak, nonsignificant, negative correlation was found between work stress and physical activity (Spearman correlation coefficient r = −0.0326, P = 0.7448). A majority of the population had moderate physical activity levels (46%) and low work stress levels (47%). Interestingly, a strong negative correlation between physical activity and stress was found among those who worked in hospitals (Spearman coefficient r = −0.795, P = 0.003).

Conclusion:

The results suggest that work-related stress is significantly associated with physical activity levels, but only in physiotherapists who work in a hospital setting.
Preliminary survey on the distribution of ixodid ticks in domestic ruminants and vegetation of Pathanamthitta district, Kerala, South India
Authors: Sahina S , Sithalakshmi S , Balasubramanian R
Published: June 2024

Background & objectives:

Tick-bome diseases (TBD) are becoming a major public and animal health problem in Kerala state of India. During 2021–2022, a new focus of tick nuisance and associated fever has been reported in some villages of Pathanamthitta district of the state.

Methods:

The study on the diversity of tick fauna in Southern Kerala is limited. Therefore, a preliminary survey was carried out for the first time for implementation of future tick-borne pathogen detection and control measures. This research may provide a proper understanding of tick density and acarological risk by tick ecology through surveillance and identification. A cross-sectional study was conducted during the summer season of2021 and 2022 in the tick bite infected areas of Naduvathumoozhy, Vayakkara, Malayalappuzha and Pallikuzhi.

Results:

Ticks were manually collected from ruminants and by dragging method from vegetation. A total of727 ticks of 8 different species were collected from the genus Amblyomma, Haemaphysalis, Hyalomma, and Rhipicephalus. The most prevalent species were Haemaphysalis bispinosa and H. turturis, at 38.7% and 29.1%, respectively. Ticks were sampled from 197 animals with the proportion of infestation being 73.60%. It was highest in goats (85.9%), followed by buffalo (73.6%) and cow (65.4%).

Interpretation & conclusion:

Despite the absence of any TBD outbreaks, Pathanamthitta district has a high diversity of tick fauna and a high rate of tick infestation in domestic ruminants, especially goats. Hence, active tick surveillance is necessary in order to prevent TBD outbreaks in the future. The study also emphasizes the importance of performing tick surveillance in both Kyasanur forest disease (KFD) endemic and non-endemic regions.
The potential habitat and environmental fitness change of Aedes albopictus in Western Eurasia for 2081–2100
Authors: Trájer Attila J
Published: June 2024

Background & objectives:

The range of Aedes albopictus, the most important vector mosquito in Western Eurasia is growing due to climate change. However, it is not known how it will influence the habitats occupied by the species and its environmental fitness within its future range.

Methods:

To study this question, the habitat characteristic of the mosquito was investigated for 2081–2100.

Results:

The models suggest a notable future spread of the mosquito in the direction of Northern Europe and the parallel northward and westward shift of the southern and eastern potential occurrences of the mosquito. The models suggest a notable increase in generation numbers in the warmest quarter, which can reach 4–5 generations in the peri-Mediterranean region. However, both the joint survival rate of larvae and pupae and the number of survival days of adults in the warmest quarter exhibit decreasing values, as does the potential disappearance of the mosquito in the southern regions of Europe and Asia Minor, along with the growing atmospheric CO2 concentration-based scenarios.

Interpretation & conclusion:

While in 1970–2000 Aedes albopictus mainly occupied the hot and warm summer temperate regions of Europe, the species will inhabit dominantly the cool summer temperate (oceanic) and the humid continental climate territories of North and North-Eastern Europe in 2081–2100.
An eco-epidemiological analysis of dengue outbreak in Port Blair, South Andaman Island, India
Authors: Jena Sasmita Rani , Kaliyamoorthy M , Bhattacharyya T K , Baruah Kalpana
Published: June 2024

Background & objectives:

In Port Blair, the capital of Andaman & Nicobar Islands, in the Bay of Bengal, India, there was a sudden increase in fever cases resembling the symptoms of dengue in the monsoon period of 2022. Hence, an investigation was carried out to find out epidemiological and entomological reasons behind the outbreak.

Methods:

An entomological survey was carried out in 24 wards of Port Blair Municipal Council (PBMC) area, epidemiological data of last six years (January–December 2017–2021 and January–October 2022) and patient details of the year 2022 were collected. Both the epidemiological and entomological data were analyzed concerning time and place.

Results:

During this outbreak period tyres (22.4%) came out as a major breeding habitat followed by small discarded materials (17.5%), metal drums (15.3%), and plastic drums (11.7%). In rainy season, peri-domestic breeding (55%) was more than the domestic breeding (45%) habitat. Ae. aegypti had a high preference for indoor large containers (100-1000 L) like plastic tank, metal drum and cement tank whereasAe. albopictus prefers to breed in medium sized plastic container (20–100 L) and outdoor water receptacles like tyres, flower pots, and domestic discarded materials.

Interpretation & conclusion:

By source reduction, indoor space spray and outdoor fogging, vector density was controlled which curtailed the transmission and within eight weeks a decreasing trend of dengue cases was noticed. A regular entomological survey is crucial to know the seasonality and key breeding habitats of the vector for proper planning of vector control.
Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching
Authors: Pradeepkiran Jangampalli Adi , Rawat Priyanka , Reddy Arubala P. , Orlov Erika , Reddy P. Hemachandra
Published: June 2024

JOURNAL/nrgr/04.03/01300535-202509000-00024/figure1/v/2024-12-31T000210Z/r/image-tiff

The process of neurite outgrowth and branching is a crucial aspect of neuronal development and regeneration. Axons and dendrites, sometimes referred to as neurites, are extensions of a neuron’s cellular body that are used to start networks. Here we explored the effects of diethyl (3,4-dihydroxyphenethylamino)(quinolin-4-yl) methylphosphonate (DDQ) on neurite developmental features in HT22 neuronal cells. In this work, we examined the protective effects of DDQ on neuronal processes and synaptic outgrowth in differentiated HT22 cells expressing mutant Tau (mTau) cDNA. To investigate DDQ characteristics, cell viability, biochemical, molecular, western blotting, and immunocytochemistry were used. Neurite outgrowth is evaluated through the segmentation and measurement of neural processes. These neural processes can be seen and measured with a fluorescence microscope by manually tracing and measuring the length of the neurite growth. These neuronal processes can be observed and quantified with a fluorescent microscope by manually tracing and measuring the length of the neuronal HT22. DDQ-treated mTau-HT22 cells (HT22 cells transfected with cDNA mutant Tau) were seen to display increased levels of synaptophysin, MAP-2, and β-tubulin. Additionally, we confirmed and noted reduced levels of both total and p-Tau, as well as elevated levels of microtubule-associated protein 2, β-tubulin, synaptophysin, vesicular acetylcholine transporter, and the mitochondrial biogenesis protein–peroxisome proliferator-activated receptor-gamma coactivator-1α. In mTau-expressed HT22 neurons, we observed DDQ enhanced the neurite characteristics and improved neurite development through increased synaptic outgrowth. Our findings conclude that mTau-HT22 (Alzheimer’s disease) cells treated with DDQ have functional neurite developmental characteristics. The key finding is that, in mTau-HT22 cells, DDQ preserves neuronal structure and may even enhance nerve development function with mTau inhibition.
Indian Association for Radiation Protection Young Professionals Group (IARP YPG): A platform to unite young professionals in the field of radiation protection
Authors: Dey Riya , Dawn Sandipan , Anand S
Published: June 2024

The Indian Association for Radiation Protection (IARP) Young Professionals Group (YPG) is a national initiative aimed at fostering collaboration and communication among young researchers in radiation protection (RP) and related fields. Established in March 2023, following the Asian and Oceanic Congress for Radiation Protection (AOCRP6), IARP YPG addresses the need for a cohesive network to enhance professional growth and knowledge sharing among emerging professionals in India. IARP YPG's objectives include keeping members informed about recent developments in RP, conducting study sessions, facilitating interdisciplinary discussions etc. The group also emphasizes improving communication skills through group discussions and presentations. Since its inception, IARP YPG has organized key events, including three lecture series. To support ongoing collaboration, IARP YPG has established a Microsoft Teams platform with various channels for discussions, assignments, and sharing research. This platform enables interactive engagement, allowing members to connect and support each other's professional development. In summary, IARP YPG aims to enhance the professional growth of young RP researchers in India, promoting continuous learning, collaboration, and innovation in the field of radiation protection.
Estimation of indoor radon, thoron, and their progeny concentrations in different types of dwellings in the Kapurthala district of Punjab, India
Authors: Kumar Manish , Sharma Navjeet
Published: June 2024

A study has been carried out to assess the exposure levels due to radon, thoron, and progeny, for inhabitants of the Kapurthala district of Punjab, India. In the present investigation, the average values of radon concentration in winter, summer, and rainy seasons were found to be 27.4 ± 10.3 Bqm−3, 15.9 ± 8.0 Bqm3, and 21.1 ± 8.6 Bqm−3, respectively, while the corresponding values for thoron were 43.9 ± 20.6 Bqm−3, 28.1 ± 20.1 Bqm−3, and 34.5 ± 20.4 Bqm−3, respectively, in the Kapurthala district of Punjab. Similarly, the values of annual inhalation dose have been found to be 0.68 ± 0.23 mSvy−1, 0.42 ± 0.18 mSvy−1, and 0.54 ± 0.20 mSvy−1 in winter, summer, and rainy seasons, respectively. The results of our survey indicate that radon, thoron, and their progeny concentrations and inhalation dose are within the safe limits as prescribed by health agencies.
Sequential separation of uranium and plutonium in urine sample using UTEVA resin
Authors: Dubla Rupali , Kumar Ranjeet , Raveendran Nanda , Yadav J. R. , Sawant Pramilla D.
Published: June 2024

This article describes the process of separating uranium (U) and plutonium (Pu) sequentially in urine samples through the use of UTEVA resin. The manuscript optimizes several parameters, including the concentration of nitric acid in the loading solution, the repeatability of results across the multiple uses of the column, and most significantly, implementation of distinctive eluting agents. These eluting agents encompass a combination of 0.002M sulfamic acid and 0.002M ascorbic acid in 2M HNO3, as well as 1.5M NH2OH, HCl (hydroxylamine hydrochloride) in 2M HCl, all aimed at enhancing recovery percentages. The selection of 0.002M sulfamic acid and 0.002M ascorbic acid in 2M HNO3 have been observed to be exceptionally effective in achieving higher radiochemical recoveries. The standardized methodology presented here is characterized by its swiftness and robustness, particularly when compared to the traditional ion exchange method and numerous other published works related to extraction chromatography materials. Radiochemical recoveries for spiked urine samples of 232U and 242Pu consistently fall within the range of 93%–100% and 71%–96%, demonstrating an average recovery percentage with a standard deviation of 96.2% ±2.4% and 82.4% ±10.1%, respectively.
Hemorrhagic Shock from Acute Variceal Bleeding Caused by Sarcoidosis: A Case Report
Authors: Haaksma Mark Evert , van der Bie Sjoerd , van Soest Ellert J. , Vermin Ben , Goeijenbier Marco
Published: June 2024

Sarcoidosis is a disease of unknown etiology, characterized by noncaseating granulomas. Generally, the condition primarily manifests in the lungs. Extrapulmonary involvement is common, but localization in the gastrointestinal system is rare. Here, we present the case of a 37-year-old male who became increasingly hemodynamically unstable during the diagnostic workup for sarcoidosis due to acute variceal bleeding. The underlying mechanism was later attributed to portal hypertension caused by hepatic involvement of the disease. This case demonstrates the importance of considering variceal hemorrhage as a rare but life-threatening complication of gastrointestinal localization of sarcoidosis.
Enhancing the Central Venous Catheterization Competency of Medical Students through a Specialized Team and an Interactive Response System: A pre–post study
Authors: Tsai Yuan-Ming , Lin Szu-Yu , Huang Go-Shine , Liu Feng-Cheng , Chang Yaw-Wen , Lin Chin-Sheng
Published: June 2024

Background:

Central venous catheterization (CVC) is a critical clinical procedure. To avoid complications, possessing good knowledge regarding the CVC care bundle and skills for the proper insertion and maintenance of CVC are important.

Objectives:

To evaluate the effectiveness of an educational intervention and the use of an interactive response system in enhancing the CVC bundle care and insertion skills of medical students undergoing critical care medicine training.

Materials and Methods:

Sixth-year medical students (equivalent to fourth-year students in the United States) engaged in didactic lessons, interactive demonstrations, and simulator training facilitated by a CVC team comprising three thoracic and two vascular surgeons (all with a minimum 5 years of experience in central venous access) during their intensive care unit (ICU) rotation. Self-reported knowledge and confidence levels were assessed using pre-and posttests administered through the Zuvio App, an interactive response system.

Results:

A total of 60 students underwent the educational intervention, of which 54 completed the pretest and 40 completed the posttest. In the posttest, significant improvement was found in the CVC bundle care competency and understanding (P = 0.002), preprocedural preparation (P = 0.002), insertion procedures (P = 0.004), complications (P = 0.003), and insertion depth decisions (P = 0.001). Staff and students reported that assessment and interaction via the Zuvio App were valuable, practical, and feasible in a clinical setting, providing trainees with an individual competency portfolio of receiving precise medical education.

Conclusions:

Integrating the training provided by a specialized team with an interactive response system enhanced the knowledge and competency level in CVC insertion among medical students in this study.
Review article: Diagnosis and management of enlarged extraocular muscles
Authors: Abouelatta Mahmoud Mostafa , Shalaby Osama El Saied , Awara Amr Mahmoud , Kikkawa Don Osami , Eldesouky Mohammed Ashraf
Published: June 2024

Extraocular muscle (EOM) enlargement may be due to a variety of causes. These causes can be classified in three ways: according to pathogenesis and histopathological features, according to the site, and according to the clinical features. Diagnosis of the cause is dependent upon history, clinical examination, and investigations. Imaging with computed tomography or magnetic resonance imaging and muscle biopsy is typically necessary to make the correct diagnosis. Treatment of the patient must be directed toward the specific cause. This review emphasizes important clinical and pathological guidelines for appropriate diagnosis and treatment of patients with EOM enlargement.
Primary congenital glaucoma: We are always on the way
Authors: Yang Hongfang , Lu Wenhan , Sun Xinghuai
Published: June 2024

Primary congenital glaucoma (PCG), a developmental glaucoma occurring due to angle anomaly, earns growing concerns among ophthalmologists for its vision-damaging attribute. The incidence of PCG varies among races and geographic regions and is mostly genetically associated. Theories have been posed in attempt to address the etiology of this congenital maldevelopment and in the meanwhile providing evidence for feasibility of PCG surgeries. In regard to the clinical aspects of this entity, both the clinical characteristics and general principals of management are introduced, with angle surgeries highlighted for clarifying details including their success rates, key points for a successful surgical intervention, postoperative management, and follow-up strategies. Taking patients’ vision-associated quality of life into consideration, we stressed that further perceptual learning and low vision rehabilitation are momentous. However, much has yet to be elucidated in respect of the truly comprehensive pathogenesis underneath as well as means by which clinical outcomes of PCG can be further improved. We are now looking forward to innovative therapeutic approaches like gene therapy in specific genes in the future, with the hope of improving their life-long visual quality in those young patients.
Impact of coronavirus disease 2019 restrictions on the efficacy of atropine 0.01% eyedrops for myopia control – Findings from the Western Australia Atropine for the Treatment of Myopia study
Authors: Lee Samantha Sze-Yee , Lingham Gareth , Mackey David A.
Published: June 2024

This study explored the impact of short-term coronavirus disease 2019 (COVID-19) restrictions on the efficacy of atropine 0.01% eyedrops on myopia control in a multiethnic cohort of Australian children. In the Western Australia Atropine for the Treatment of Myopia study, 104 and 49 children were randomized to receive atropine 0.01% eyedrops and a placebo, respectively. We compared the 1-year myopia progression and axial elongation following the 2-month lockdown in 2020 to the same months in 2019 and 2021, i.e., the 1-year myopia progression up to May 2019–October 2019 (non-COVID-19) versus the 1-year progression up to May 2020–October 2020 (COVID-19 period), and the 1-year progression up to May 2021–October 2021 (non-COVID-19) versus the 1-year progression up to the same months in 2020. After excluding participants who withdrew, completed their treatment phase prior May 2020, or those whose study visits did not fall between May 2020 and October 2020, 65 participants (mean age at baseline = 11.8 ± 2.5 years) were included in the final analysis (49 in the treatment group; 16 in the placebo group). After correcting for age, sex, and ethnicity, there was no significant main effect of the short-term lockdown on the rate of spherical equivalent or axial length change. However, there was a lockdown × treatment interaction effect on the rate of axial elongation (P = 0.007). This was such that in the treatment group, the 1-year axial elongation was faster during lockdown by 0.056 mm compared to the nonlockdown periods (P = 0.009), while the rate of axial elongation in those on the placebo eye drops was similar during lockdown and nonlockdown. Our findings suggest that there is a decreased efficacy of low-concentration atropine even with relatively lenient restrictions lasting for a few months.
Middle Triassic basaltic pyroclastic rocks from the Mt. Medvednica ophiolitic mélange (NW Croatia): petrology, geochemistry and tectono-magmatic setting
Authors:   Croatian Geological Survey, Zagreb, Croatia, Slovenec Damir , Halamić Josip ,   Croatian Geological Survey, Zagreb, Croatia, Šegvić Branimir ,   Department of Geosciences, Texas Tech University, USA
Published: June 2024

Hectometric blocks of Middle Triassic mafic pyroclastic rocks, represented by volcanic agglomerates/breccias and lapilli tuffs, form part of the ophiolitic mélange of Mt. Medvednica, situated in the southwestern segment of the Zagorje-Mid-Transdanubian Zone. These rocks share petrochemical characteristics with pyroclastic derivatives of alkali, within-plate basaltic lavas of Mts. Medvednica, Samoborska Gora, and Kalnik, indicating the occurrence of explosive events preceding the dominant effusive submarine volcanism during the Middle Triassic (Illyrian-Fassanian?) stages. The formation of these pre-ophiolitic pyroclastics is associated with an intracontinental rift setting and reflects melts derived from an OIB-type enriched mantle plume source. These pyroclastics represent uncontaminated melts that erupted through a highly thinned continental crust. In geodynamic terms, the formation of pyroclastites occurred during the Late Anisian-Early Ladinian along the continental margin of Palaeotethys through the proto back-arc rifting of continental lithosphere (Adria Plate), leading to the formation of the Maliak/Balkan Neotethys Rift, in the emerging northwestern segment of Neotethys. The investigated pyroclastic rocks of Mt. Medvednica document the extension in an evolved intracontinental rift basin, which immediately preceded the generation of the initial Neotethyan oceanic lithosphere during the Upper Triassic.
Problem epidemii dżumy podczas wyprawy Napoleona do Egiptu w latach 1798–1801
Authors: Turos Maria Joanna
Published: June 2024

Napoleon’s Egyptian campaign not only led to the discovery of the monuments of the pharaonic state, but also opened a new chapter in medical science. Encounter with many epidemic and endemic diseases has led to rationalization of views on the spread of infections. This was the case, among others, in the case of the plague, epidemics of which often broke out in the Middle East, practically at the gates of Europe. Creating a model of sanitary procedures contributed to reducing the risk.
Exploring The Meaning Of Islamic Accounting Courses For Students: A Phenomenological Approach
Authors: Husain Fauziah , Aisyah Mitra Riani , Musa Nurain
Published: June 2024

This research aims to explore the meaning of Islamic accounting courses for students. This qualitative research uses an interpretive paradigm and a transcendental phenomenological approach. The data source uses primary data with observation and interview data collection techniques, where the research informants are 20 students who have programmed Islamic accounting courses in the Islamic accounting study program at IAIN Sultan Amai Gorontalo. Before data analysis is carried out, a data validity test consists of credibility, dependability and confirmability tests. This research shows that learning Islamic accounting courses must focus on developing student competencies, optimizing business processes, and developing Islamic accounting applications. This research can contribute to developing academic literature on Islamic accounting by expanding understanding of the effectiveness of learning models on students' understanding of Islamic accounting courses. This research can contribute to universities improving and enhancing Islamic accounting learning models, making them more relevant and valuable for students in the world of work.
Performance Of The National Zakat Agency Based On Financial Ratios
Authors: Lenap Indria , Karim Nina Karina , Sasanti Elin Erlina
Published: June 2024

This research aims to analyze the performance of BAZNAS Central Lombok Regency based on financial ratios. The type and research approach used is quantitative descriptive. This research uses secondary data from BAZNAS Central Lombok Regency financial reports for 2018-2022. The research results show that the activity ratio value indicates that BAZNAS Central Lombok has effectively distributed Zakat, Infaq, and Shadaqah (ZIS) funds. The turnover ratio shows very high/active performance, whereas the performance of ZIS fund distribution is excellent in time. The efficiency ratio shows that the ratio of collection costs is efficient, the operational cost ratio using the total operational costs divided by total ownership rights approach is inefficient, while the operational cost ratio using the total operational costs divided by total collection approach is efficient, as well as the human resource cost ratio. The amil fund ratio and liquidity ratio show good performance. On the other hand, the growth ratio shows poor performance. Theoretically, this research can be used as a reference for future research. Practically, this research can be a reference material for BAZNAS Central Lombok Regency, which has not yet entirely produced optimal performance and for the Central Lombok Regency government as the regulator so that it can mobilize the community and government officials in distributing zakat to BAZNAS Central Lombok Regency.
C/EBPα-mediated epigenetic control of liver disorders in young children
Authors: Gulati Ruhi , Timchenko Nikolai
Published: June 2024

Despite a young age and limited exposure to nutritional challenges and other diseases, young children can develop liver disorders such as fatty liver, fibrosis, and liver cancer. The preliminary stages of these disorders are silent, and the patients come to the clinic at a late stage. During studies of pediatric liver cancer hepatoblastoma (HBL), our group found that a portion of our fresh HBL biobank is characterized by the development of Non-Alcoholic Fatty Liver Disease (NAFLD) including fatty liver, fibrosis, and increased proliferation. Our studies and other recent reports revealed that liver cancer and these fatty liver-specific disorders are strongly correlated with epigenetic changes in gene expression independent of HBL mutations. One of the mutation-independent pathways we focused on is the phosphorylation/de-phosphorylation status of C/EBPα at Ser190 (Ser193 in the mouse C/EBPα protein). De-phosphorylated C/EBPα loses its ability to interact with the chromatin remodeling protein p300, reducing transcription of the genes containing C/EBPα binding sites in their promoters. We found that the lack of the S193 phosphorylation of C/EBPα in S193A mice prevents the development of NAFLD in mouse models of pre-natal and post-natal high-fat diet-mediated NAFLD [1]. In this review, we present extended studies of NAFLD in both mouse models and HBL patients, which revealed the critical role of proliferation in the development of pediatric fatty liver disorders. Since Ser190 of C/EBPα is phosphorylated by cyclin D1-dependent kinase CDK4, our findings provided a rationale for the consideration of CDK4 inhibitors as potential drugs for the prevention of NAFLD and liver cancer in young kids. This review summarizes our findings and available data from other groups demonstrating the critical role of C/EBPα-dependent epigenetic pathways in the development of liver disorders in young children.
EVALUASI PENATAAN FASILITAS TERMINAL TIPE C UNTUK MENINGKATKAN EFISIENSI OPERASIONAL (STUDI KASUS TERMINAL TIPE C SEMANGGI)
Authors: Wiguna I Wayan Yudi Martha , Elang Ramadhani Subagyo  , A.A Bagus Oka Khrisna Surya
Published: June 2024

Semanggi Type C Terminal is located in Pasar Kliwon District, Surakarta City, whichhas an area of 2,111 m² and serves 2 urban public transportation routes totaling 45 operating fleets. The facilities available at Semanggi Terminal in accordance with PM 40 of 2015 concerning Road Transport Passenger Service Standards are only 42% ofthe total facilities and lack of private vehicle parking capacity. This study aims toevaluate the needs of terminal facilities and provide layout proposals for both facilitylayout design to circulation and parking lot layout design. By using terminal inventorysurvey data and other supporting data which is then carried out optimizationanalysis, the existing condition of Semanggi Terminal facilities and the need for ideal private vehicle parking space are produced. The results of this study can provideresults in the form of recommendations for the area of Semanggi Terminal facilityneeds of 61.54 m², circulation proposals to reduce existing conflict points by 35% and 50%, and the arrangement of private vehicle parking lots that can be used as park and ride facilities from those that can initially accommodate 17 SRP to 21 SRP according to the Decree of the Director General of Land concerning TechnicalGuidelines for Parking Implementation.
AERODYNAMIC CALCULATION OF THE COMBINE HARVESTER CLEANING SYSTEM IN 2D FORMULATION
Authors:   OJSC “Gomselmash”, KALINOUSKI Аliaksandr А.
Published: June 2024

The paper presents the methodology of modelling air flows in the flow area of the air-screen cleaning system of a combine harvester in two-dimensional formulation. Recommendations are given on parameters adjustment of the computational fluid dynamics software package Ansys Fluent. An example is provided on aerodynamic calculation of cleaning system two-dimensional model. According to the estimation of the results of experimental studies and modelling, the error was not more than 10 %. Recommendations are formulated on the cleaning system design to obtain uniform airflow across its width. The application of this methodology makes it possible to carry out the model calculation on a personal computer without using clusters or high-performance servers. The obtained results will be subsequently used in further research of the combine harvester cleaning system.
RESEARCH OF THE COMPOSITION INFLUENCE OF COMPOSITES CONTAINING IMPACT DIAMONDS ON THEIR PERFORMANCE CHARACTERISTICS IN BLADE PROCESSING OF NON-FERROUS METALS
Authors:   Joint Institute of Mechanical Engineering of the NAS of Belarus, SENYUT Vladimir T. , VITYAZ Petr A. ,   National Academy of Sciences of Belarus, ZHORNIK Viktor I. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, VALKOVICH Igor V. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus, AFANASYEV Valentin P. ,   V.S. Sobolev Institute of Geology and Mineralogy of the Siberian Branch of the RAS, GRIGORIEV Igor E. ,   Belarusian State Technological University
Published: June 2024

The paper presents the results of resistance tests of tool composite materials containing nanostructured impact diamonds, in comparison with composites based on synthetic superhard materials, diamond and cubic boron nitride (cBN), and ВК-8 (VK-8) (WC + 8 % Co) hard alloy, during blade processing of workpieces made of brass ЛС-59 (LS -59) (57–60 % Cu) and aluminum alloy AK-7 (Al 92–94 %, Si 6–8 %). Samples of composite materials for wear resistance studies were obtained by thermobaric sintering in a highpressure apparatus. The performance of composites was assessed by the wear of the cutter back surface, as well as by a specially developed method for studying the performance characteristics of composite superhard materials, based on determining their specific productivity. As a result of the tests, it is found that composites based on impact diamonds have the highest resistance when turning non-ferrous metal alloys. In particular, the wear resistance of a composite material containing impact diamonds with the addition of cBN exceeds the wear resistance of cutters made of composite 02 (belbor) by 1.5–3 times, and that of cutters made of hard alloy VK-8 by 8–10 times. Additions of impact diamond to hard alloy in the amount of 6.25 and 12.5 vol.% increase the relative wear resistance of the hard alloy composite compared to the original VK-8 alloy by 10–15 and 20–25 %, respectively.
Usos adecuados de suelo en tres parroquias del cantón Cuenca-Ecuador Caso: Sayausí, San Joaquín y Baños
Authors: Quezada Hernán Patricio Morejón
Published: June 2024

Las actividades antrópicas en el Ecuador han crecido en los últimos años, generando el aumento del uso de suelo urbano, el consumo de nuevos suelos para la agricultura y la disminución de suelos de carácter de conservación. Este fenómeno establece conflictos entre los diferentes usos de suelo, por tal razón el presente trabajo presenta un acercamiento a la realidad de dicha problemática, tomando como zona de estudio las parroquias rurales de Sayausí, San Joaquín y Baños en el cantón Cuenca (Ecuador). El objetivo de este estudio es identificar la aptitud del territorio para tres usos de suelo: urbano, agrícola y de conservación; estableciendo la vocación de cada uno de ellos y los posibles conflictos que se generan por la idoneidad de una misma área para diferentes usos de suelo. La metodología propuesta abarca la implementación de Sistemas de Información Geográfica (SIG) y la evaluación multicriterio (EMC) para obtener como resultado tres mapas de aptitud continua, a partir del establecimiento de criterios generados en el estudio bibliográfico y del análisis de experiencias metodológicas similares. Posteriormente, a través del modelo de resolución estandarizado Land Use Conflict Identification Strategy (LUCIS) se establecen las zonas de posibles conflictos entre las aptitudes de uso de suelos.
Fish Welfare – A Case Study: Reviling for the first-time side effects of vaccination in European sea bass (Dicentrarchus labrax) and barramundi (Lates calcarifer) in the Israeli fish farming
Authors: Smirnov Margarita , Hershko Hanna , Ron Tetsuzan B
Published: June 2024

Vaccination is an effective way to control many infectious diseases in fish. Israeli fish farming has successfully used two vaccines over the last 30 years and has no problem with the side effects of vaccination. However, after introducing new species, a new problem emerged: these fish, after vaccination, demonstrated peritoneal lesions such as granulomas. At the same time, the fish did not show retarded growth or suffering during the fattening period. This study was conducted to establish the connection between vaccination and the appearance of granulomas. Evidence drawn from this research work and comparing vaccinated and non-vaccinated fish confirms that intraperitoneal granulomas do not impact the growth, performance, or fish fillet quality at harvest.
Corporate Social Responsibility, Corporate Financial Performance and the Confounding Effects of Economic Fluctuations
Authors: Lestari Vivi Duwi , Soraya Aya , Hwihanus Hwihanus
Published: June 2024

This study aims to explore the relationship between Corporate Social Responsibility (CSR) and corporate financial performance in five different countries: USA, UK, Germany, Japan, and Australia. Data is obtained from studies that measure CSR through various metrics, such as CSR Index, CSR Score, CSR Disclosure, CSR Rating, and CSR Spending, while financial performance is measured using various indicators such as Return on Assets (ROA), Return on Equity (ROE), Net Profit Margin, Tobin's Q, Operating Income, and Market Value. Data analysis was performed using linear regression statistical methods to evaluate the relationship between CSR variables and financial performance. It found that there was a significant positive relationship between CSR and corporate financial performance in all countries studied. Companies that are more active in CSR activities tend to record better financial performance. Variations between countries suggest that local context influences the strength of these relationships. The managerial implication of these findings is that investing in CSR can improve a company's reputation, strengthen its position in the market, and improve long-term financial performance. However, further studies are still needed to understand the factors influencing the relationship between CSR and financial performance across various industry and geographic contexts.
Pola Asuh Orang Tua Karo: Mempertahankan Identitas Budaya dan Pembentukan Karakter Anak Usia Dini
Authors: Tambunan Devi Kristina , Purba Jesica Mariani , Tarigan Yosh Eva Arina , Kartika Jelni , Toruan Gladys Lumban
Published: June 2024

Pembentukan karakter anak usia dini dipengaruhi oleh pola asuh orang tua, terutama dalam melestarikan identitas budaya. Artikel ini mengeksplorasi pola asuh orang tua Karo di Sumatera Utara dalam mempertahankan identitas budaya dan pembentukan karakter anak usia dini. Dilakukan penelitian kualitatif dengan pendekatan deskriptif di Kabanjahe Kabupaten Karo, dengan subjek single parent, tokoh adat, dan orang tua. Metode pengumpulan data meliputi wawancara, observasi, dan dokumentasi. Hasilnya menunjukkan bahwa pola asuh orang tua Karo sangat terkait dengan kebiasaan dan tradisi turun-temurun, mengajarkan nilai-nilai seperti gotong royong dan penghormatan kepada leluhur. Identitas budaya yang kuat ini memainkan peran signifikan dalam cara orang tua Karo membesarkan anak-anak mereka. Pola asuh dalam masyarakat Karo tidak hanya berfokus pada pemenuhan kebutuhan fisik dan emosional anak, tetapi juga pada penanaman nilai-nilai budaya dan tradisi. Strategi pola asuh ini melibatkan pembelajaran berbasis pengalaman, melalui aktivitas sehari-hari dan upacara adat. Nilai-nilai budaya Karo, seperti gotong royong dan penghormatan terhadap leluhur, ditanamkan sejak dini, membentuk karakter anak yang kuat dan berakar pada budaya Karo.
Mengenal Ras, Budaya dan Pola Pengasuhan Di Desa Susuk, Kec. Tiganderket, Kab. Karo
Authors: Purba Asmarani , Surbakti Insenamira Br , Sari Raudah Permata , Panjaitan Yunintan
Published: June 2024

Tujuan penelitian ini adalah untuk mengetahui bagaimana ras, budaya dan pola pengasuhan yang ada di suku Karo, metode dalam penelitian ini menggunakan metode kualitatif, data dikumpulkan melalui teknik wawancara langsung. subjek dalam penelitian ini adalah masyarakat suku Karo di desa Susuk, kec. Tiganderket, Kab. Karo, dengan beberapa narasumber diantara kepala desa, ketua adat dan masyarakat Karo. Hasil penelitian menunjukkan bahwa kebudayaan di suku Karo tidak terlalu mengalami perubahan dari tahun ke tahun dan tetap dengan peraturan yang dulu, pola asuh suku Karo cenderung keras dilihat dari permainan anak yang ada di suku ini yang melibatkan fisik anak ikut terluka dan tidak memandang temen bermain baik perempuan maupun laki - laki, ras pada suku ini memiliki hidung yang mancung dikarenakan memiliki nenek moyang dari suku India.
A Study of Communication Strategies used by English Teachers and its Implication in Teaching English as a Foreign Language
Authors:   Student of Master of English Education, University of Lampung, Indonesia, Yulianti Dwi
Published: June 2024

The objective of this research was to analyze the English teachers’ communication strategies and their perception during the teaching learning process. The writer analyzed the data gained through the questionnaire by describing the English teachers’ perception about the communication strategies usually used during the teaching learning process. She also analyzed the teachers’ communication strategies into the fourteen strategies based on to some experts, there are several types of communication strategies that can be used to solve problems in communication (Dornyei 1995, Littlewood 1984, Tarone 1980). (Tarone (1980) presents five types of communication strategies, including: paraphrase, transfer, appeal for assistance, mime, avoidance. Littlewood (1984) describes eight types of communication strategies: they are avoidable communication, adjust the message, use paraphrase, use approximation, create new words, switch to the native language, use non-linguistic resources, seek for help. Meanwhile, Dornyei (1995) stated that the three main types of communication strategies, namely: topic avoidance strategies (topic avoidance and message abandonment), compensatory strategies (approximation, word coinage, circumlocution, literal translation, code-switching, appeal for help, used all-purpose words, non-linguistic signal, foreignizing), and stalling or time gaining strategies (use of fillers/hesitation devices). The design of this research is qualitative research. The writer described the data in order to have a clear and complete description of the research result. The researcher used the result of the English teachers’ questionnaire as the data. The sample of this research was the English teacher who lives and teach in Bandar Lampung in the academic year 2022/2023.
The Influence of Company Growth, Capital Structure, and Business Risk on Company Value with Company Size as a Moderating Variable in Property and Real Estate Sector Companies on the Indonesia Stock Exchange
Authors:   Faculty of Economics and Business, University of North Sumatra, Medan, Indonesia, Simatupang Anastasia Miranda Rebecca , Arif Nasution Abdillah ,   Faculty of Economics and Business, University of North Sumatra, Medan, Indonesia, Bulan Siregar Narumondang ,   Faculty of Economics and Business, University of North Sumatra, Medan, Indonesia
Published: June 2024

This research aims to analyze the influence of company growth, capital structure, and business risk on company value. This research also aims to analyze company size in moderating the relationship between company growth, capital structure and business risk on company value. The population in this study were property and real estate sector companies listed on the Indonesia Stock Exchange from 2018 to 2022. The sampling technique in this study used purposive sampling, so the sample obtained were 33 companies. The analysis technique used in this research uses panel data regression analysis using EViews 13 as a data processing tool. The results of this research prove that capital structure has a positive effect on company value, while company growth and business risk have a negative effect on company value. Company size is not able to moderate the relationship between company growth, capital structure, and business risk on company value.