bluuebunny/crossref_metadata_2025 huggingface dataset:
Convergencias y Divergencias en la Integración Sudamericana
Authors: Vaillant Marcel
Published: April 2022

This paper analyses the recent evolution of economic integration in South America, identifying the heterogeneous strategies that have been implemented. The analysis distinguished between issues that are a potential source for conflict, and issues where there exists a wider scope for achieving common objectives. Two levels of integration are considered: sub-regional (CAN and MERCOSUR) and multilateral (ALADI, CASA, ALABA). Each of these two types has different requirements as well as different aims. While the former involves deeper compromises, multilateral agreements have a more disperse agenda with less strict clauses. The different proposals are analysed from four perspectives: convergence of the agreements, integration in infrastructure and the development of regional goods, asymmetries and convergence, and institutional issues. The main conclusion is that countries involved in the integration process are far from fulfilling with a fundamental premise: to believe in what they agree and to agree in what they believe.
Variables económicas y político-institucionales aplicadas al análisis del gasto público subnacional en Argentina
Authors: Rezk Ernesto
Published: April 2022

Using a panel data with fixed effect for the period 1993-2004, we aim at ascertaining whether the participation of public expenditure categories in total public spending of Argentine provinces was influenced by economic, fiscal and politico-institutional variables, such as provinces’ political sign; possibility of reelection of the executive branch; provisions limiting public spending, public debt, or restrictions to the use of credit; and the structure of the legislative bodies. While estimated coefficients for fiscal effort, financial sufficiency, and public debt were significantly different from zero, results fell short of being conclusive for the other variables, except for categorical variables standing for limits on spending and credit use.
Sobre Política Agraria Argentina en el Período 1933-2007
Authors: Colomé Rinaldo Antonio
Published: April 2022

This paper analyzes Argentina’s economic policy in relation to the agricultural sector, specifically those measures implemented since 1933. When possible, we point out the enunciated foundations of these policies; make systematization, and try to detect its effects on the agrarian sector, according sub-periods on the base of the predominant economic ideas which inspired the implemented policies. Three key instruments that can be said constitute specific agrarian policies were detected: external commercial policy (“export taxes”), exchange rate policy, and price policy. It is not an objective of the paper to do an exhaustive analysis of the whole period, but rather we concentrate on those sub-periods that were rich in policies generation. It is concluded that specific agricultural economic policies were initially designed to unrest the effects of the crisis at the beginning of thirties, and were thought as transitory. These policies tented to favor the sector and, through it, the country. As time moved forward, they became clearly discriminatory against the sector.
CATENA OF ABILITY UTILIZATION, INSTITUTION, BUSINESS DEALING AND BUSINESS CONDENSE
Authors:   Department Of Business, University Of Lahore, Pakistan, khan Mo. Salim , Bee Amina ,   Department Of Business, University Of Lahore, Pakistan
Published: April 2022

This study analyzed the effect of Ability utilization, establishments and monetary Dealing on business development of Pakistan for the time of 1985-2014. Vector blunder adjustment model is applied to dissect the short run and long run relationship among factors. Assessed outcomes uncover that Ability utilization, institutional quality, monetary Dealing, work and capital emphatically affect business development while shopper value record and loan fee adversely affect monetary development of Pakistan. It is proposed that administration should build the interest in Ability area and work on the institutional quality in the country while monetary changes and rebuilding of monetary area will advance private loaning so joblessness will be decreased.
Cambios en la comprensión de las relaciones entre polígonos en estudiantes de 8-9 años
Authors: Bernabeu Melania , Moreno Mar , Llinares Salvador
Published: April 2022

El objetivo de este estudio es identificar cambios en la comprensión del concepto de polígono y la relación entre polígonos en estudiantes de tercero de educación primaria al participar en un experimento de enseñanza. Analizamos 59 respuestas de estudiantes a un cuestionario, antes y después de una secuencia de enseñanza considerando las nociones de deconstrucción dimensional y aprehensiones cognitivas mediante el uso del software CHIC. Los cambios muestran una mayor coordinación de las aprehensiones al razonar con los atributos no relevantes para la definición de polígono que apoya la generación de clases de polígonos. Estos cambios subrayan el carácter multifacético de la deconstrucción dimensional y la importancia de las aprehensiones cognitivas en el desarrollo del pensamiento geométrico y en particular en la comprensión de las relaciones entre polígonos en estudiantes de primaria.
Líneas argumentativas de profesores de biología sobre el origen del coronavirus SARS-CoV-2
Authors: Salazar-López Tatiana Iveth , Carrillo-Tripp Mauricio
Published: April 2022

En esta investigación nos proponemos avanzar sobre el estudio de la incorporación de pruebas para argumentar. Partimos de la cuestión sociocientífica del SARS-CoV-2 utilizando una noticia mediática acerca de su creación en el laboratorio. El objetivo fue describir la evolución de líneas argumentativas realizadas por cuatro profesores en un curso de una maestría profesionalizante en Educación en Biología. Analizamos los argumentos escritos en un cuestionario en dos momentos, por medio de un modelo de seis niveles epistémicos considerando el uso de datos y teorías para construir una conclusión sobre la noticia. Los resultados evidencian que no se incorporaron datos del nivel epistémico asociado a la estructura primaria en ninguno de los momentos. Sin embargo, se encontraron cambios respecto al nivel epistémico asociados a la estructura terciara y cuaternaria del virus.
Agricultural Reforms in India
Authors: Dev Mahendra
Published: April 2022

Issue: Jan-Feb 2021

This paper explores the recent farm laws passed by parliament and their impact on farmers’ income.  The laws collectively offer greater freedom to cultivators to sell their produce at better prices and allow farmers to enter into contracts with processors, aggregators, wholesalers, large retailers and exporters at mutually agreed crop prices. The laws also encourage private investment into storage and warehousing by removing stockholding limits. To make these reforms work, some conditions may have to be fulfilled and imperfections and concerns have to be addressed, which are elaborated in the paper. Finally, the paper focuses on other agricultural reforms to improve the supply-side factors, such as rationalization of subsidies, land reforms, use of technology, strengthening institutions and governance, and improving rural infrastructure.
Grants from Centre and States’ Fiscal Marksmanship
Authors: Srinivasan Sharmadha , Misra Prakhar
Published: April 2022

Issue: Jan-Feb 2021

In this paper, we aim to establish the issues with fiscal marksmanship of states’ revenue budgets. We particularly focus on the grants received from the Union government. Within grants, we find state plan schemes and centrally sponsored schemes to be the most volatile. Our analysis looks at three key stakeholders in the budget-making process and their role in poor fiscal marksmanship. These are the Centre, the states and the Finance Commission. The actuals could miss budget estimates due to the Centre misprojecting its revenues or expenditures, the states misprojecting their revenues, or the Finance Commission making errors while recommending grants. Poor estimation methods, weak capacity in drawing up budgets and implementing projects, specific conditionalities imposed either by the Centre or the Finance Commission and exogenous and random shocks that cannot be controlled for — all affect marksmanship of the states’ revenue budgets.
India’s Free Trade Agreements
Authors: Krishna Pravin
Published: April 2022

Issue: Mar-Apr 2021

This paper reviews India’s experience with the free trade agreements (FTAs) that it signed over the last two decades. The trade outcomes under the agreements are found to be quite modest: The trade shares of India’s FTA partners stayed nearly constant over the past decade, and trade deficits with FTA partners, as a share of the overall deficit,  did not increase over time. These findings challenge the assertion that India’s trade agreements have led to a widening of trade deficits and that they were responsible for the stagnation of the Indian manufacturing sector.
Kajian Keanekaragaman Famili Papilionaceae di Kawasan Mangrove Sebagai Buku Saku berbasis 3D Pageflip
Authors: Nadha Rama Fara , Dharmono Dharmono , Riefani Maulana Khalid
Published: April 2022

Papilionaceae adalah satu dari banyak keanekaragaman hayati di Indonesia, yang mempunyai ciri buah polong, mempunyai sistem pertumbuhan berbentuk perdu, herba, pohon hingga membelit, kebanyakan ditemukan berbentuk pohon dan membelit, sangat mudah diamati karena memiliki tipe buah dengan adanya sifat-sifat dan karakteristik pada bunganya. Tujuan penelitian ini yaitu (1) Mendeskripsikan keanekaragaman spesies Papilionaceae mangrove Desa Sungai Bakau, (2) Mendeskripsikan validitas buku saku 3D Pageflip keanekaragaman spesies Papilionaceae mangrove Desa Sungai Bakau, (3) Mendeskripsikan kepraktisan buku saku 3D Pageflip keanekaragaman spesies Papilionaceae mangrove Desa Sungai Bakau. Metode penelitian menggunakan pendekatan deskriptif dengan pengembangan evaluasi formatif Tessmer (1998) dibatasi hanya pada alur pengembangan (1) self evaluation; (2) expert review; dan (3) one-to-one. Hasil pengamatan menunjukkan, bahwa keanekaragaman spesies Papilionaceae ditemukan 6 spesies, yaitu: Crotalaria pallida, Clitoria fragrans, Derris trifoliata, Grona triflora, Desmodium heterocarpon, dan Canavalia cathartica. Hasil validitas Buku Saku spesies Papilionaceae berbasis 3D Pageflip didapatkan skor rata-rata 91,67% termasuk dalam kategori sangat valid dan hasil uji kepraktisan isi Buku Saku spesies Papilionaceae berbasis 3D Pageflip didapatkan skor rata-rata 86,90% dengan kriteria sangat praktis.
Etnobotani Hanjuang di Desa Sabuhur Kabupaten Tanah Laut Sebagai Buku Ilmiah Populer
Authors: Najmah Laily , Dharmono Dharmono , Riefani Maulana Khalid
Published: April 2022

Etnobotani merupakan ilmu tentang mempelajari pemanfaatan suatu tumbuhan oleh masyarakat, adat, atau suku bangsa tertentu. Potensi local sekitar lingkungan dapat dijadikan sumber belajar, khususnya tumbuhan dalam lingkup etnobotani. Hanjuang memiliki penyebaran dan manfaat di Desa Sabuhur. Penelitian ini bertujuan untuk mengkaji etnobotani Hanjuang di Desa Sabuhur, mengetahui validitas, serta kepraktisan isi buku yang dikembangkan sebagai Buku Ilmiah Populer. Metode pada penlitian dengan pendekatan deskriptif untuk mendeskripsikan kajian etno-botani Hanjuang dengan melakukan wawancara menggunakan teknik snowball sampling dan penelitian pengembangan menggunakan evaluasi formatif Tessmer melalui tahapan self evaluation, expert review dan one to one. Hasil penelitian menunjukkan 6 kajian etnobotani yaitu Hanjuang merupakan tumbuhan perdu (botani) yang digunakan masyarakat Desa Sabuhur sebagai obat hipertensi (farmakologi), serta sebagai tanaman hias yang ditanam di pekarangan rumah (ekologi). Hanjuang digunakan sebagai bahan untuk upacara adat mandi-mandi pengantin (sosioantropologi), dan bisa dijual sebagai tanaman hias (ekonomi). Penamaan hanjuang sebagai ‘pawang’  dipercaya dapat menangkal makhluk halus (linguistik). Hasil pengembangan Buku Ilmiah Populer pada expert review dari dua validator memiliki Validitas Sangat Valid dengan persentase 94,7% dan hasil kepraktisan isi dari tiga orang mahasiswi Pendidikan Biologi FKIP ULM Banjarmasin yang telah menempuh mata kuliah Etnobotani dan lulus dengan nilai A mendapatkan  persentase 93,0% dengan kriteria Sangat Baik.
Pemanfaatan Powerpoint Interaktif Sebagai Media Pembelajaran Dalam Hybrid Learning
Authors: Wulandari Eka
Published: April 2022

Pandemi COVID 19 yang melanda dunia selama hampir dua tahun akhir-akhir ini telah mempengaruhi semua sendi kehidupan masyarakat. Kegiatan-kegiatan yang secara normal biasanya dilakukan dengan bertatap muka langsung saat ini harus dialihkan ke sistem daring sepenuhnya ataupun sebagian. Sektor pendidikan adalah salah satu aspek yang terpengaruh karena adanya perubahan yang mendadak ini. Proses pembelajaran saat ini dialihkan menggunakan sistem hybrid learning, dimana beberapa penyesuaian harus dilakukan untuk tetap mencapai target pembelajaran yang maksimal. Salah satu media pembelajaran yang cukup menarik yang dapat dimanfaatkan dalam hybrid learning ini adalah dengan menggunakan aplikasi PowerPoint interaktif yang terbukti mampu meningkatkan minat dan motivasi siswa, serta meningkatkan prestasi belajar mereka.
Peningkatan Kinerja Guru Melalui Supervisi Edukatif Kolaboratif Secara Periodik Di SMAN 3 Kota Bima Tahun Pelajaran 2020/2021
Authors: Syaiful Syaiful
Published: April 2022

Penelitian ini bertujuan untuk mengetahui peningkatan kinerja guru melalui supervisi edukatif kolaboratif secara periodik di SMAN 3 Kota Bima Tahun Pelajaran 2020/2021. Jenis penelitian adalah Penelitian Tindakan Sekolah (PTS), yang dirancang dalam dua siklus, tiap siklus terdiri dari empat tahapan, yaitu: perencanaan, pelaksanaan, pengamatan, dan refleksi. Subyek dalam penelitian ini adalah guru SMA Negeri 3 Kota Bima sebanyak 20 orang. Instrument yang digunakan adalah Lembar Observasi dan Lembar Evaluasi kegiatan. Analisis data menggunakan analisis deskriptif dan disajikan dalam  persentase. Berdasarkan analisis data, yang telah dilakukan maka dapat disimpulkan bahwa terjadi peningkatan kinerja guru dari 73,89% pada siklus I menjadi 97,22% pada siklus II melalui supervisi edukatif kolaboratif secara periodik di SMAN 3 Kota Bima Tahun Pelajaran 2020/2021
Validitas Dan Keterbacaan Buku Saku Elektronik Di SMA Tentang Pteridophyta Di Bantaran Sungai Irigasi Rawa Desa Tanipah Kecamatan Mandastana
Authors: Yusuf Novita Anggriani , Hardiansyah Hardiansyah , Noorhidayati Noorhidayati
Published: April 2022

Ditemukannya berbagai jenis Pteridophyta di kawasan Bantaran Sungai Irigasi Rawa Desa Tanipah Kecamatan Mandastana dapat dijadikan sebagai bahan pengayaan berbasis potensi lokal pada materi konsep plantae sub konsep Pteridophyta di SMA. Penelitian ini bertujuan untuk mendeskripsikan keanekaragaman Pteridophyta di Bantaran Sungai Irigasi Desa Tanipah Kecamatan Mandastana. Pengumpulan data diperoleh dengan teknik jelajah total pada bagian kiri dan kanan Bantaran Sungai Irigasi Rawa Desa Tanipah. Hasil identifikasi yang didukung oleh literatur kemudian dibuat menjadi sebuah buku saku elektronik. Pengembangan buku saku elektronik berbasis Flip HTML 5 menggunakan model Borg and Gall (1989). Buku saku elektronik dilakukan uji validasi dengan 3 validator ahli. Uji keterbacaan dilakukan oleh 9 orang peserta didik SMAN 1 Mandastana. Hasil Penelitian ditemukan ada 5 Familia yang terdiri dari 6 spesies Pteridophyta yaitu : Stenochlaena palustris, Lygodium microphyllum (Cav.) R. Br. Nephrolepis hirsutula, Pityrogamma calomelanos, Pteris vitatta L, dan Salvinia molesta. Uji validasi buku saku elektronik diperoleh nilai sebesar 87,46% dengan kriteria (Sangat Valid). UJi keterbacaan oleh peserta didik  diperoleh nilai sebesar 89,62% dengan kriteria (Sangat Baik).
Inclusiveness of European Union labour markets in relation to young people
Authors: Bal-Domańska Beata
Published: April 2022

In the recent years the professional situation of young people (aged 15–24) compared to that of older age groups (referred to as adults) has deteriorated. In 2020 the unemployment rate among young people in 23 European Union countries (in 19 countries in 2019, which was the last year before the outbreak of the COVID-19 pandemic) was, compared to 2003, significantly higher than that of adults, showing a growing gap between the situation of these two groups of workers on the labour market. The aim of the paper is to assess the situation of young people on the EU labour markets. The analyses based on data obtained from Eurostat cover the years 2003–2020. For the purposes of the analyses, the concept of ‘labour market inclusiveness’ was introduced, understood as a feature of the economy in which access to jobs is similar for all groups of economically active people. The inclusiveness of the national labour markets in the EU has been defined from a static and long-term perspective. For the long-term approach, the method of statistical measurement of α inclusiveness was applied. The final result of the analysis is a typology of the EU labour markets developed on the basis of the proposed definitions, taking into account the level of inclusiveness and the availability of jobs for young people and adults. The research confirms that the national labour markets are considerably diversified. These differences are visible in terms of the unemployment of young people and adults, the reaction of markets to economic shocks and the level of labour market inclusiveness.
AI in Pharmaceutical Companies
Authors: Gleixner Michael F.
Published: April 2022

The concrete realization of AI endeavors is challenging, especially for established companies. In this paper, essential requirements from theory and practice are analyzed holistically and applicable solutions are discussed. It incorporates insights from conducted case studies and expert interviews in the pharmaceutical industry.

This work contributes to support previous research on how efficient, (ethically) responsible and human-centered AI solutions can be integrated into the business model of scientifically oriented fields (such as Medical Affairs). In this context, the role of management and interdisciplinary professionals is highlighted and the development of an AI framework is proposed.
Therapeutic Properties of Trichinella spiralis (Nematoda) in Chronic Degenerative Diseases
Authors: Nevárez-Lechuga Christian-Irene , Meza-Lucas Antonio , Escobar-Gutiérrez Alejandro , Wong-Baeza Carlos , Baeza Isabel , de-la-Rosa-Arana Jorge-Luis
Published: April 2022

Diseases produced by helminth parasites occur frequently in underdeveloped countries where they present a serious public health problem. At the same time, in these regions, a lower rate of autoimmune and allergic diseases has been observed. Due to these observations, some researchers have proposed that some helminths, such as Trichinella spiralis or its proteins, have strong anti-inflammatory potential, or have assessed them as modulating agents of the immune response. T. spiralis shifts the host immune response from a Th1 profile, characterized by pro-inflammatory cytokines, to a Th2 profile, characterized by the release of different cytokines with anti-inflammatory properties. This parasite has shown high therapeutic potential in a wide variety of disease models. In one of the most promising, the experimental lupus model in mice, the release of anti-inflammatory cytokines IL-4 and IL-10 and delayed onset of the key clinical features of the experimental lupus model for at least 5 months were observed, when previously parasitized. This is the first study to date that focuses on the use of T. spiralis as an immunomodulator in lupus disease. In conclusion, further study of the immune response generated by the parasite is necessary to advance the development of new therapies for inflammatory diseases.
Health Promotion for AMD and the Role of Nutrition
Authors: Martinez Alexander , J. Pizzimenti Joseph , W. Lem Drake , Gunvant Davey Pinakin
Published: April 2022

There is an increase in demand for health promotion and preventative medicine playing a vital role in managing chronic illnesses. Many of these conditions stem from a poor diet, sedentary lifestyle and smoking, all of which are risk factors for age-related macular degeneration (AMD). To combat chronic diseases, the root of the conditions may be addressed through the concept of health promotion. Health promotion thoroughly assesses how a population’s environmental, political, socioeconomic, behavioral, and cultural practices influence its health. This concept can be applied in a primary care setting which takes on a broader approach in treating and managing patients. Primary care providers need to be aware of the connections between common chronic illnesses and AMD. All primary care providers and eyecare specialists must be patients’ advocate and help improve their systemic and ocular prognosis.
Gaming the System?: Justice, Fairness, and Disability Accommodations
Authors: Cureton Adam ,   Philosophy Documentation Center
Published: April 2022

I am legally entitled to certain accommodations for my visual impairment that I do not always need. Affording me these rights is required by justice even on those rare occasions in which they are not necessary to give me an equal opportunity to fully participate in all aspects of society. I sometimes wonder whether I am nonetheless “gaming the system,” “exploiting a loophole,” or otherwise acting unjustly or unfairly by using disability accommodations in such circumstances. The essay aims to explore this apparent paradox by considering whether it is sometimes wrong, as a matter of justice, for disabled people to use accommodations we are justly owed. My conclusion is that, although it is not unjust for disabled people to use accommodations we are entitled to as a matter of justice, an ideally just person would sometimes forgo them for the sake of her commitment to justice itself.
Arboreal gems: resurrection of Isometrus sankeriensis Tikader & Bastawade, 1983 and descriptions of two new species of Isometrus Ehrenberg, 1828 (Scorpiones: Buthidae) from the Western Ghats, India
Authors: Sulakhe Shauri , Deshpande Shubhankar , Gowande Gaurang , Dandekar Nikhil , Ketkar Makarand
Published: April 2022

The Western Ghats of India is considered one of the richest biodiversity hotspots in the world. Documenting scorpion diversity has always been of paramount importance due to their species richness, ecological role and endemism, which calls for conservation priority. Scorpion diversity of the Western Ghats is probably underestimated given the ancestry of the group, and more field work in the region is very likely to uncover numerous undescribed taxa. Several new Indian species have recently been discovered in the scorpion genus Isometrus Ehrenberg, 1828 (Scorpiones: Buthidae). In this communication, we resurrect I. sankeriensis Tikader & Bastawade, 1983 and describe two new species from the Western Ghats of India, I. nakshatra sp. nov. and I. wayanadensis sp. nov., using an integrative taxonomic approach. In order to replace the lost holotype of I. sankeriensis, we designate a neotype and reassess the identity of this species. This work elevates the number of species of Isometrus found in India to eight and we expect many more scorpion discoveries from India with continued research.
Children’s Learning of a Semantics-Free Artificial Grammar with Center Embedding
Authors: Ojima Shiro , Okanoya Kazuo
Published: April 2022

Whether non-human animals have an ability to learn and process center embedding, a core property of human language syntax, is still debated. Artificial-grammar learning (AGL) has been used to compare humans and animals in the learning of center embedding. However, up until now, human participants have only included adults, and data on children, who are the key players of natural language acquisition, are lacking. We created a novel game-like experimental paradigm combining the go/no-go procedure often used in animal research with the stepwise learning methods found effective in human adults’ center-embedding learning. Here we report that some children succeeded in learning a semantics-free artificial grammar with center embedding (A2B2 grammar) in the auditory modality. Although their success rate was lower than adults’, the successful children looked as efficient learners as adults. Where children struggled, their memory capacity seemed to have limited their AGL performance.
Carta para Sofia: Um manifesto amoroso
Authors: Azevedo Sônia Machado
Published: April 2022

O texto pretende ser um manifesto, em forma epistolar, sobre as confluências entre pesquisa, arte e vida, no sentido de refletir sobre a academia e as relações acadêmicas estabelecidas entre orientação e pessoa orientanda, visando lançar luz ao como se investiga e se instiga a investigar, observando os processos experimentados em direção à produção tal qual uma doula acompanha uma gestação, com rigor e responsabilidade tais que podem superar normas e modos tradicionais de se encarar uma pesquisa e seus resultados finais.
(des)educação estética em Weapon is a part of my body: Corpo e política em discurso
Authors: Gonçalves Jean Carlos , Gonçalves Michelle Bocchi
Published: April 2022

O artigo apresenta reflexões desencadeadas a partir do espetáculo Weapon is a part of my body, uma coprodução entre Brasil, Israel e Reino Unido, com atuação do brasileiro Pedro Granato e da israelense Ruthie Osterman, tomando como princípio norteador o conjunto de potencialidades que a obra oferece para se pensar o que nomeamos, neste ensaio, como (des)educação estética e suas reverberações para os debates sobre corpo e política na cena contemporânea. O quadro teórico-metodológico tem sua moldura envernizada pela Análise Dialógica do Discurso. Elegemos como texto base o ensaio O problema do conteúdo, do material e da forma na criação literária, escrito por Bakhtin em 1934, no qual o autor oferece elementos para uma reflexão sobre estética geral.
Reflorestar o pensamento ou Ações Performágycas y o ator-xamã
Authors: Pury Way , Prymeyra Carolina , Vermelho Malandro , Castro Thalita
Published: April 2022

Ao longo desse artygo foram abordadas aproxymações possýveys entre as artes da cena, com ênfase no teatro-performatyvo, y a performatyvydade dos xamanysmos yndýgenas das terras bayxas da Améryca do Sul. Tomado como conceyto tensyonador a ydeya corporyfycada de ator-xamã, buscou-se neste escryto evydencyar/cryar certos fluxos entre um y outro, ysto é, entre o ator-performer y o xamã yndýgena, partyndo tanto da ydeya de experyêncya y da anályse de prátycas empýrycas, como da cura(dorya) de dyferentes vozes - de pesquysadores, acadêmycos, lýderes yndýgenas, xamãs etc. - que foram postas em dyálogo. Apesar de não haver um aprofundamento teóryco em conceytos especýfycos - em certo sentydo - chamou-se para dançar aquy algumas sementes de pensamento, tays quays, ações performágycas, trabalho do ator sobre sy, a ydeya de andança, a efetyvydade dos sonhos, o não-método, dentre outras ymagens e encantamentos que não se deyxam capturar. Nhauêra abre os camynhos para a floresta do pensar.
Atuar-atuado: cena, pajelança e uma possível rotação de perspectiva
Authors: Brito Katia
Published: April 2022

“Atuado” é o termo usado na Pajelança Cabocla de Pena e Maracá para se referir ao corpo em performance da pajé. Este artigo trouxe a proposição de uma aproximação dessa prática e algumas reflexões sobre os possíveis diálogos da noção de atuado com a contemporaneidade das artes cênicas e performativas. Para tanto, partiu-se da hipótese de que esse cruzamento oferece elementos com valor de fertilidade para uma cena que ensaia novos modos de pensar e ver os mundos. A proposição se origina do encontro da autora deste artigo com a memória da própria avó, pajé cabocla de pena e maracá, e imbricou trabalhos de campo no Marajó com questões das Artes da Cena e pensamentos que discutem e desdobram o conceito de perspectivismo ameríndio.
“Salamandra”: Filosofia-Performance, corpo e saúde holística
Authors: Vieira Alba Pedreira
Published: April 2022

A partir da Prática Artística como Pesquisa e da Filosofia-Performance, problematizo como o  corpo performático constrói, reconstrói e cambia sentidos de fenômenos diversos, ampliando entendimentos do movimento e do gesto como exercício filosófico e aliados a dimensões de saúde holística. Compartilho trabalhos em que seres se movem enquanto geram autoconhecimento, potência energética e espiritualizada relacionadas à qualidade de vida. A Performance “Salamandra” (2018) e o projeto de intercâmbio artístico “Salamandra” (2020), foram realizados em momentos de doenças, dores e aflições. Reflexões complexificam conexões teórico-práticas e alargam pensamentos sobre cura, ciência, realidade, corpo, filosofia, performance, cognição, imaginação e arte.
Vulgar sem ser sexy: Corpo, trabalho e cena na poesia de Mila Teixeira
Authors: Riscado Caio
Published: April 2022

O artigo tem como objeto a análise de poemas do livro A proclamação da vulgaridade ou quantos furos uma calcinha pode ter?, da poeta, roteirista e dramaturga Mila Teixeira, publicado pela editora Urutau, em 2021. A partir da noção de crueldade em Artaud, o texto busca uma aproximação com o anúncio da vulgaridade, proclamado pela escritora. Através do destaque de versos que sugerem a confluência entre vida e obra, a poesia é analisada pela perspectiva do trabalho em arte como prática de investigação do corpo e recriação das relações. Os relatos e imagens compartilhados pela autora são interpretados como situações cênicas que revelam a manifestação de um estado-poético-teatral em sua produção. Por fim, a escrita autoficcional é abordada como proposição para a expansão dos espaços de escuta e compartilhamento das experiências encarnadas.
A cena como campo ampliado: o ambiente e o Viewpoints
Authors: Brasil Giselly
Published: April 2022

Este artigo apresenta considerações sobre a cena como campo ampliado a partir da noção de ambiente presente em propostas e projetos de Richard Schechner e Hélio Oiticica e de perspectivas da prática dos Viewpoints. Propõe-se aqui um olhar para a abertura da cena a partir de iniciativas que articulam corpo, espaço e tempo nos processos de criação. Schechner e Oiticica lançam propostas ambientais que ampliam as possibilidades de reflexão sobre o fenômeno da arte como espaço de relação no tempo e no espaço. O Viewpoints, por sua vez, estimula a investigação desse campo ambiental do ponto de vista da prática e da experiência da cena. Pretende-se assim, abordar perspectivas de uma cena ampliada levando-se em consideração a noção de ambiente, bem como das experiências ambientais propostas pelo Viewpoints.
Grupo de teatro e teatro de grupo na Colômbia parte 1: um estudo remoto em Medellín
Authors: Trotta Rosyane
Published: April 2022

O artigo se baseia em pesquisa que teve como fonte as páginas virtuais de grupos teatrais da cidade de Medellín, prefeitura, imprensa, festivais e revistas acadêmicas. Depois de apresentados os conceitos envolvidos e a metodologia, buscam-se os aspectos em comum e observam-se as especificidades de cada conjunto, tendo como fonte principal seus textos de autodefinição. O que pode uma pesquisa remota, na busca de pistas de um teatro de grupo?
Asthma Control Level and Relating Socio-Demographic Factors in Hospital Admissions
Authors: Yalçınkaya Gönül , Kılıç Mahmut
Published: April 2022

Purpose: Asthma is one of the serious public health problems that we face today and the rate of complete control is very low. This study aims to determine the level of asthma control and its relationship with socio-demographic factors in asthma patients.

Methods: This cross-sectional study was conducted between November 2020-April 2021 among people aged 18-64 who applied to the hospital and were not diagnosed with asthma. The data of the research were made with the personal information form, ACT (asthma control test). ACT is a questionnaire consisting of 5 questions. Patients rate each question between one and five points. The total score of the five questions forms the test result. If the total score is 25, it is considered as full control, 24-20 as partial control, and ≤19 as not under control. In the research, 206 people participated.

Results: Of the participants, 60.7% were female, 60.2% had a family history of asthma, 94.2% of them used asthma medication, and the average age was 45.7±13.85. In the last 12 years, 50.5% of asthma patients stated that they applied to the emergency department due to respiratory problems, and 23.3% were hospitalized due to these problems. It was determined that 78.6% of asthma patients were not under control, 21.4% were under partial control, and there was no patient under full control. The mean age (48.8) and body mass index (BMI) (29.4) of those whose asthma was not under control were higher than those with partial control (32.2 and 24.7, respectively) (p<0.001). It has been determined that the probability of asthma not being controlled increases as age and BMI increase, and life satisfaction decreases, and it is higher in quit smokers than in current smokers (p<0.05).

Conclusion: Asthma is largely uncontrolled. The rate of uncontrolled asthma increases with increasing age and BMI. Patients with high BMI should be supported to lose weight and should be directed to exercise.
Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology
Authors: Thompson John A. , Schneider Bryan J. , Brahmer Julie , Achufusi Amaka , Armand Philippe , Berkenstock Meghan K. , Bhatia Shailender , Budde Lihua E. , Chokshi Saurin , Davies Marianne , Elshoury Amro , Gesthalter Yaron , Hegde Aparna , Jain Michael , Kaffenberger Benjamin H. , Lechner Melissa G. , Li Tianhong , Marr Alissa , McGettigan Suzanne , McPherson Jordan , Medina Theresa , Mohindra Nisha A. , Olszanski Anthony J. , Oluwole Olalekan , Patel Sandip P. , Patil Pradnya , Reddy Sunil , Ryder Mabel , Santomasso Bianca , Shofer Scott , Sosman Jeffrey A. , Wang Yinghong , Zaha Vlad G. , Lyons Megan , Dwyer Mary , Hang Lisa
Published: April 2022

The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to provide guidance on the management of immune-related adverse events resulting from cancer immunotherapy. The NCCN Management of Immunotherapy-Related Toxicities Panel is an interdisciplinary group of representatives from NCCN Member Institutions, consisting of medical and hematologic oncologists with expertise across a wide range of disease sites, and experts from the areas of dermatology, gastroenterology, endocrinology, neurooncology, nephrology, cardio-oncology, ophthalmology, pulmonary medicine, and oncology nursing. The content featured in this issue is an excerpt of the recommendations for managing toxicities related to CAR T-cell therapies and a review of existing evidence. For the full version of the NCCN Guidelines, including recommendations for managing toxicities related to immune checkpoint inhibitors, visitNCCN.org.
Warm education for people's livelihood and well-being: Private enterprises explore the implementation of the Ministry of Education's supply and demand matching employment and education project
Authors: WANG Xiaodong
Published: April 2022

In order to promote the organic linkage between employment and training, and the effective connection between supply and demand of talents, the Ministry of Education implemented supply and demand matching employment education project in 2021 for the first time. Aiming at how to make the employment and training of students form an organic linkage as soon as possible, do a good job in the effective connection between the supply and demand of talents, help college students to establish a correct outlook on life, career selection and employment as soon as possible, and help user units to cultivate and recruit more practical, complex According to its own actual situation, Sophia Technology (Shenzhen) Co., Ltd. has carried out the specific practice of the 2021 supply and demand matching employment and education project. This paper communicates and discusses from the aspects of cognitive understanding of the project, grasp of the review process, and data analysis of the project.
Assessment of genotyping markers in the molecular characterization of a population of clinical isolates of Fusarium in Colombia
Authors: Velásquez-Zapata Valeria , Palacio-Rúa Katherine , Cano Luz E. , Gaviria-Rivera Adelaida
Published: April 2022

Introduction: Fusarium is a very heterogeneous group of fungi, difficult to classify, with a wide range of living styles, acting as saprophytes, parasites of plants, or pathogens for humans and animals. Prevalence of clinical fusariosis and lack of effective treatments have increased the interest in the precise diagnosis, which implies a molecular characterization of Fusarium populations.Objective: We compared different genotyping markers in their assessment of the genetic variability and molecular identification of clinical isolates of Fusarium.Materials and methods: We evaluated the performance of the fingerprinting produced by two random primers: M13, which amplifies a minisatellite sequence, and (GACA)4, which corresponds to a simple repetitive DNA sequence. Using the Hunter Gaston Discriminatory Index (HGDI), an analysis of molecular variance (AMOVA), and a Mantel test, the resolution of these markers was compared to the reference sequencing-based and PCR genotyping methods.Results: The highest HGDI value was associated with the M13 marker followed by (GACA)4. AMOVA and the Mantel tests supported a strong correlation between the M13 classification and the reference method given by the partial sequencing of the transcription elongation factor 1-alpha (TEF1-α) and rDNA 28S.Conclusion: The strong correlation between the M13 classification and the sequencingbased reference together with its higher resolution demonstrates its adequacy for the characterization of Fusarium populations.
Caracterización de las lesiones personales en el sistema estomatognático valoradas en el Instituto Nacional de Medina Legal y Ciencias Forenses, Regional Suroccidente, entre 2015 y 2020
Authors: Castañeda Lina-Alexandra , Quintero María-Paula , Moreno-Correa Sandra-Milena , Moreno-Gómez Freddy , Vázquez-Escobar Ruby-Amparo
Published: April 2022

Introducción. El dictamen de lesiones personales hace precisiones sobre el daño ocurrido en el cuerpo o en la salud de una persona. La valoración del odontólogo es de gran importancia en los casos en que se ha visto afectado el sistema estomatognático.Objetivo. Caracterizar las lesiones personales que afectaron el sistema estomatognático como producto de actos violentos en 266 casos valorados en el Instituto Nacional de Medina Legal y Ciencias Forenses, Regional Suroccidente, entre 2015 y 2020.Materiales y métodos. Se hizo un estudio descriptivo de corte transversal de las lesiones personales que afectaron el sistema estomatognático. Se incluyó información del dictamen de lesiones personales obtenida de la plataforma del Sistema de Información Forense de Clínica de Colombia (SICLICO) y asociada con la naturaleza de la lesión, las secuelas y la incapacidad médico-legal.Resultados. Se observó una mayor frecuencia de agresores y de víctimas masculinas (94,4 y 64,3 %, respectivamente), especialmente en el grupo etario entre los 21 y los 30 años (32,6 %). Los contextos más frecuentes fueron los de violencia interpersonal (76,3 %) y violencia de pareja (19,9 %). El principal mecanismo de agresión fue el contundente (88,0 %). Las lesiones reportadas en tejidos blandos (83,5 %) afectaron tejidos periodontales (48,9 %) y labios (28,6 %) con edema (32,7 %) y heridas (22,9 %), en tanto que, en tejidos duros (55,1 %), afectaron los dientes (41,4 %) por fractura complicada en tercio cervical (19,2 %) y avulsión (18 %). Predominó la incapacidad definitiva (64,7 %), seguida de la de 20 días (28,6 %) y las secuelas funcionales (24,1 %).Conclusiones: Los tejidos periodontales y los dientes fueron las estructuras más afectadas, lo que ocasionó incapacidades considerables, y dejó secuelas funcionales y estéticas principalmente entre los hombres en edad productiva.
Detección molecular de Toxoplasma gondii en carnes para consumo humano en Ibagué, Colombia
Authors: Medina Hernández Juan David , Osorio Delgado Laura Alejandra , Zabala Gonzalez Daniel , De Almeida Vitor Ricardo Wagner , Gómez Jorge Enrique , Carranza Julio César , Vallejo Gustavo Adolfo
Published: April 2022

Introducción. Toxoplasma gondii es un parásito con gran potencial zoonótico que puede infectar un amplio rango de huéspedes de sangre caliente, incluidos los animales del sector pecuario, lo que causa pérdidas a la industria. En el humano, es patógeno en personas inmunosuprimidas y afecta el desarrollo del feto en infecciones congénitas. Además, se asocia con diversos trastornos del comportamiento en personas sanas. El humano puede adquirir T. gondii al consumir carnes contaminadas mal cocidas.Objetivo. Determinar la positividad de T. gondii en carnes de consumo humano (res, pollo y cerdo) en Ibagué, Colombia.Materiales y métodos. Se utilizó la PCR convencional anidada y la secuencia del gen B1 de T. gondii como blanco de amplificación. Se tomaron 186 muestras de carne comercializada en la zona urbana de Ibagué (62 de res, 62 de pollo y 62 de cerdo) y se obtuvo el porcentaje de positividad en cada tipo de carne evaluada.Resultados. Se encontró un porcentaje de positividad de 18,8 % en las muestras, siendo la carne de cerdo la del mayor porcentaje (22,5 %; 14/62), seguida por las muestras de carne de res (19,3 %; 12/62) y de pollo (14,5 %; 9/62). Los mejores productos amplificados fueron secuenciados en Macrogen, y alineados con las secuencias del gen B1 depositadas en el GenBank, con lo que se confirmó su identidad.Conclusiones. Este es el primer estudio sobre prevalencia de T. gondii en carnes para consumo humano en Ibagué y el departamento del Tolima. Se demostró que los tres tipos de carne representan un riesgo para la infección en humanos a nivel local.
The regulation of hsacirc_004413 promotes proliferation and drug resistance of gastric cancer cells by acting as a competing endogenous RNA for miR-145-5p
Authors: Zhou Fusheng , Ding Weiqun , Mao Qiqi , Jiang Xiaoyun , Chen Jiajie , Zhao Xianguang , Xu Weijia , Huang Jiaxin , Zhong Liang , Sun Xu
Published: April 2022

Background

Whether circRAN, which acts as a microRNA sponge, plays a role in 5-fluorouracil (5-Fu) resistant gastric cancer has not been reported. In this study, a 5-Fu resistant cell line with an IC50 of 16.59 µM was constructed.

Methods

Using comparative analysis of circRNA in the transcriptomics of resistant and sensitive strains, 31 differentially expressed circRNAs were detected, and the microRNA interacting with them was predicted.

Results

Hsacirc_004413 was selected for verification in drug resistant and sensitive cells. By interfering with hsacirc_004413 using antisense RNA, the sensitivity of drug resistant cells to 5-Fu was significantly promoted, and the apoptosis and necrosis of the cells were significantly increased. In sensitive cells, inhibition by inhibitors enhanced the resistance of cells to 5-Fu. We hypothesize that hsacirc_004413 makes gastric cancer cells resistant to 5-Fu mainly through adsorption of miR-145-5p.
Antagonistic co-contraction can minimize muscular effort in systems with uncertainty
Authors: Koelewijn Anne D. , Van Den Bogert Antonie J.
Published: April 2022

Muscular co-contraction of antagonistic muscle pairs is often observed in human movement, but it is considered inefficient and it can currently not be predicted in simulations where muscular effort or metabolic energy are minimized. Here, we investigated the relationship between minimizing effort and muscular co-contraction in systems with random uncertainty to see if muscular co-contraction can minimize effort in such system. We also investigated the effect of time delay in the muscle, by varying the time delay in the neural control as well as the activation time constant. We solved optimal control problems for a one-degree-of-freedom pendulum actuated by two identical antagonistic muscles, using forward shooting, to find controller parameters that minimized muscular effort while the pendulum remained upright in the presence of noise added to the moment at the base of the pendulum. We compared a controller with and without feedforward control. Task precision was defined by bounding the root mean square deviation from the upright position, while different perturbation levels defined task difficulty. We found that effort was minimized when the feedforward control was nonzero, even when feedforward control was not necessary to perform the task, which indicates that co-contraction can minimize effort in systems with uncertainty. We also found that the optimal level of co-contraction increased with time delay, both when the activation time constant was increased and when neural time delay was added. Furthermore, we found that for controllers with a neural time delay, a different trajectory was optimal for a controller with feedforward control than for one without, which indicates that simulation trajectories are dependent on the controller architecture. Future movement predictions should therefore account for uncertainty in dynamics and control, and carefully choose the controller architecture. The ability of models to predict co-contraction from effort or energy minimization has important clinical and sports applications. If co-contraction is undesirable, one should aim to remove the cause of co-contraction rather than the co-contraction itself.
Putting small and big pieces together: a genome assembly approach reveals the largest Lamiid plastome in a woody vine
Authors: Fonseca Luiz Henrique M. , Nazareno Alison G. , Thode Verônica A. , Zuntini Alexandre R. , Lohmann Lúcia G.
Published: April 2022

The plastid genome of flowering plants generally shows conserved structural organization, gene arrangement, and gene content. While structural reorganizations are uncommon, examples have been documented in the literature during the past years. Here we assembled the entire plastome of Bignonia magnifica and compared its structure and gene content with nine other Lamiid plastomes. The plastome of B. magnifica is composed of 183,052 bp and follows the canonical quadripartite structure, synteny, and gene composition of other angiosperms. Exceptionally large inverted repeat (IR) regions are responsible for the uncommon length of the genome. At least four events of IR expansion were observed among the seven Bignoniaceae species compared, suggesting multiple expansions of the IRs over the SC regions in the family. A comparison with 6,231 other complete plastomes of flowering plants available on GenBank revealed that the plastome of B. magnifica is the longest Lamiid plastome described to date. The newly generated plastid genome was used as a source of selected genes. These genes were combined with orthologous regions sampled from other species of Bignoniaceae and all gene alignments concatenated to infer a phylogeny of the family. The tree recovered is consistent with known relationships within the Bignoniaceae.