bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 3 from Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as Being Genes in Regions Associated with Adverse Survival
Authors: Boyd Kevin D. , Ross Fiona M. , Walker Brian A. , Wardell Christopher P. , Tapper William J. , Chiecchio Laura , Dagrada GianPaolo , Konn Zoe J. , Gregory Walter M. , Jackson Graham H. , Child J. Anthony , Davies Faith E. , Morgan Gareth J.
Published: April 2023

PDF file - 9KB
Supplementary Table 2 from Prolonged Postovulatory Proinflammatory Signaling in the Fallopian Tube Epithelium May Be Mediated through a BRCA1/DAB2 Axis
Authors: Tone Alicia A. , Virtanen Carl , Shaw Patricia , Brown Theodore J.
Published: April 2023

PDF file, 43K, NFκB-regulated and inflammation-related genes differentially expressed in FTEb(S) samples (n=4) relative to remaining FTE samples (n=20).
Supplementary Table 1 from Prolonged Postovulatory Proinflammatory Signaling in the Fallopian Tube Epithelium May Be Mediated through a BRCA1/DAB2 Axis
Authors: Tone Alicia A. , Virtanen Carl , Shaw Patricia , Brown Theodore J.
Published: April 2023

PDF file, 156K, NFκB-regulated and inflammation-related genes used for gene expression analysis.
Supplementary Figure 1 from Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein
Authors: Crane Courtney A. , Han Seunggu J. , Ahn Brian , Oehlke Jessica , Kivett Valerie , Fedoroff Anne , Butowski Nicholas , Chang Susan M. , Clarke Jennifer , Berger Mitchel S. , McDermott Michael W. , Prados Michael D. , Parsa Andrew T.
Published: April 2023

PDF file, 17162K, Model of HSPPC-96 mechanism of action.
Supplementary Figures 1 - 6 from VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy
Authors: Riquelme Erick , Suraokar Milind , Behrens Carmen , Lin Heather Y. , Girard Luc , Nilsson Monique B. , Simon George , Wang Jing , Coombes Kevin R. , Lee J. Jack , Hong Waun Ki , Heymach John , Minna John D. , Wistuba Ignacio I.
Published: April 2023

PDF file - 453KB, Figure 1. EZH2, VEGFR-2 and miR-101 expression in in additional cell lines. Figure 2. Effect of VEGF stimulation in the E2F expression. Figure 3. Effect of Hypoxia in the expression of EZH2,HIF-1alpha and miR-101. Figure 4. Effect of miR-101 overexpression in the expression of EZH2. Figure 5. Effect of treatment with DZNep on lung adenocarcinoma cell viability. Figure 6. Effect of VEGFR-2 overexpression in sensitivity to cisplatin.
Supplementary Figure Legend from The Relationship Between Homologous Recombination Repair and the Sensitivity of Human Epidermis to the Size of Daily Doses Over a 5-Week Course of Breast Radiotherapy
Authors: Somaiah Navita , Yarnold John , Daley Frances , Pearson Ann , Gothard Lone , Rothkamm Kai , Helleday Thomas
Published: April 2023

PDF file, 48K.
Supplementary Figure 3 from In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement
Authors: Benzaïd Ismahène , Mönkkönen Hannu , Bonnelye Edith , Mönkkönen Jukka , Clézardin Philippe
Published: April 2023

PDF file - 844K, Expression of adhesion molecules in cancer cell lines
Supplementary Figure 3 from Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
Authors: Lionetti Marta , Musto Pellegrino , Di Martino Maria Teresa , Fabris Sonia , Agnelli Luca , Todoerti Katia , Tuana Giacomo , Mosca Laura , Gallo Cantafio Maria E. , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Caravita Tommaso , Omede' Paola , Morabito Fortunato , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino
Published: April 2023

PDF file - 199K, Mir-301a/b ACVR1 anticorrelation in MM.
Supplementary Table 1 from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

XLS file, 28K, Distribution of clinical characteristics of MBC cases.
Supplementary Figure Legend from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

PDF file, 79K.
Supplementary Figure 3 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 29KB, Figure S3. Performance of CHEMO and SAL groups on the cued memory test administered at baseline. Errors represent the mean number of errors /day in finding the submerged platform over 5 days of testing. (Error bars denote � SEM)
Supplementary Table 6C from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Authors: Yap Timothy A. , Walton Mike I. , Grimshaw Kyla M. , te Poele Robert H. , Eve Paul D. , Valenti Melanie R. , de Haven Brandon Alexis K. , Martins Vanessa , Zetterlund Anna , Heaton Simon P. , Heinzmann Kathrin , Jones Paul S. , Feltell Ruth E. , Reule Matthias , Woodhead Steven J. , Davies Thomas G. , Lyons John F. , Raynaud Florence I. , Eccles Suzanne A. , Workman Paul , Thompson Neil T. , Garrett Michelle D.
Published: April 2023

XLS file - 103K, Gene Ontology (GO) analysis for genes significantly altered in expression by AT13148 ranked according to the P-value of a modified Fisher's exact test (EASE score, DAVID) for enriched Gene Ontology terms
Supplementary Figure Legends 1-2 from Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of HRAS, TP53, and TGFBR1
Authors: Arnault Jean Philippe , Mateus Christine , Escudier Bernard , Tomasic Gorana , Wechsler Janine , Hollville Emilie , Soria Jean-Charles , Malka David , Sarasin Alain , Larcher Magalie , André Jocelyne , Kamsu-Kom Nyam , Boussemart Lise , Lacroix Ludovic , Spatz Alain , Eggermont Alexander M. , Druillennec Sabine , Vagner Stephan , Eychène Alain , Dumaz Nicolas , Robert Caroline
Published: April 2023

PDF file - 72K
Supplementary Figure 1 from HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s
Authors: Li Ling , Tang Wenhua , Wu Xiaoqing , Karnak David , Meng Xiaojie , Thompson Rachel , Hao Xinbao , Li Yongmin , Qiao Xiaotan T. , Lin Jiayuh , Fuchs James , Simeone Diane M. , Chen Zhi-Nan , Lawrence Theodore S. , Xu Liang
Published: April 2023

PDF file - 147K, Oncomine data analysis of CD147 expression in pancreatic cancer and its co-expression genes (related to the 7th paragraph of Introduction).
Supplementary Figure 1 from Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
Authors: Besser Michal J. , Shapira-Frommer Ronnie , Itzhaki Orit , Treves Avraham J. , Zippel Douglas B. , Levy Daphna , Kubi Adva , Shoshani Noa , Zikich Dragoslav , Ohayon Yaara , Ohayon Daniel , Shalmon Bruria , Markel Gal , Yerushalmi Ronit , Apter Sara , Ben-Nun Alon , Ben-Ami Eytan , Shimoni Avichai , Nagler Arnon , Schachter Jacob
Published: April 2023

PDF file - 112K, the correlation of different variables to one another and their p values.
Supplementary Figure 2 from Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance
Authors: Ambrosini Grazia , Pratilas Christine A. , Qin Li-Xuan , Tadi Madhavi , Surriga Oliver , Carvajal Richard D. , Schwartz Gary K.
Published: April 2023

PDF file, 1040KB, Mutant GNAQ regulates pERK levels and cell proliferation of uveal melanoma.
Supplementary Table 4 from Genomic Estimates of Aneuploid Content in Glioblastoma Multiforme and Improved Classification
Authors: Li Bo , Senbabaoglu Yasin , Peng Weiping , Yang Min-Lee , Xu Jishu , Li Jun Z.
Published: April 2023

XLS file, 193K, Selected gene expression features distinguishing non-Proneural GBM classes.
Supplementary Figure 4 from Effective Activity of Cytokine-Induced Killer Cells against Autologous Metastatic Melanoma Including Cells with Stemness Features
Authors: Gammaitoni Loretta , Giraudo Lidia , Leuci Valeria , Todorovic Maja , Mesiano Giulia , Picciotto Franco , Pisacane Alberto , Zaccagna Alessandro , Volpe Maria Giuseppa , Gallo Susanna , Caravelli Daniela , Giacone Elena , Venesio Tiziana , Balsamo Antonella , Pignochino Ymera , Grignani Giovanni , Carnevale-Schianca Fabrizio , Aglietta Massimo , Sangiolo Dario
Published: April 2023

PDF file - 122K, Representative cell sorting plots of LV-oct4.eGFP transduced cells.
Supplementary Material 6 from The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel
Authors: Pasche Nadine , Wulhfard Sarah , Pretto Francesca , Carugati Elisa , Neri Dario
Published: April 2023

PDF file, 75KB, Supplementary Material 6. Weight monitoring of immunocompetent mice treated with mIL12-F8-F8 in combination with paclitaxel depicted as percentage of intial weight. Tumor-bearing mice were treated i.v. with mIL12-F8-F8 (8.75μg, corresponding to 5μg of mIL12 equivalents, n = 5, ), paclitaxel (10mg/kg, n = 4, ), mIL12-F8-F8 (8.75μg) in combination with paclitaxel (10mg/kg) (n = 4, ) or PBS (n = 4, ). (A) In the F9 teratocarinoma model (129SvEv mice) the combination group showed weight reduction. (B) In the CT26 colon carcinoma model and (C) in the A20 lymphoma model (Balb/c mice) no toxicity was observed.
Supplementary Figure 3 from Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts
Authors: Tate Sonya C. , Cai Shufen , Ajamie Rose T. , Burke Teresa , Beckmann Richard P. , Chan Edward M. , De Dios Alfonso , Wishart Graham N. , Gelbert Lawrence M. , Cronier Damien M.
Published: April 2023

PDF file - 76KB, External validation of the biomarker model by VPC with data collected in colo-205 following daily oral dosing of 50 mg/kg of LY2835219 for 56 days or two cycles of 50 mg/kg for 21 days with a 7 day rest period.
Supplementary Figure 2 from Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts
Authors: Tate Sonya C. , Cai Shufen , Ajamie Rose T. , Burke Teresa , Beckmann Richard P. , Chan Edward M. , De Dios Alfonso , Wishart Graham N. , Gelbert Lawrence M. , Cronier Damien M.
Published: April 2023

PDF file - 71KB, VPC of the biomarker model in colo-205 xenograft bearing mice following a single 3.125, 6.25 or 12.5 mg/kg oral dose of LY2835219.
Supplementary Table 1 from Targeted MET Inhibition in Castration-Resistant Prostate Cancer: A Randomized Phase II Study and Biomarker Analysis with Rilotumumab plus Mitoxantrone and Prednisone
Authors: Ryan Charles J. , Rosenthal Mark , Ng Siobhan , Alumkal Joshi , Picus Joel , Gravis Gwenaëlle , Fizazi Karim , Forget Frédéric , Machiels Jean-Pascal , Srinivas Sandy , Zhu Min , Tang Rui , Oliner Kelly S. , Jiang Yizhou , Loh Elwyn , Dubey Sarita , Gerritsen Winald R.
Published: April 2023

PDF file - 54K, Drug exposure
Supplementary Figure 5 from Epigenetic Alteration of PRKCDBP in Colorectal Cancers and Its Implication in Tumor Cell Resistance to TNFα-Induced Apoptosis
Authors: Lee Jin-Hee , Kang Min-Ju , Han Hye-Yeon , Lee Min-Goo , Jeong Seong-In , Ryu Byung-Kyu , Ha Tae-Kyu , Her Nam-Goo , Han Jikhyon , Park Sun Jin , Lee Kil Yeon , Kim Hyo-Jong , Chi Sung-Gil
Published: April 2023

PDF file - 72K
Supplementary Figure 2 from Targeted MET Inhibition in Castration-Resistant Prostate Cancer: A Randomized Phase II Study and Biomarker Analysis with Rilotumumab plus Mitoxantrone and Prednisone
Authors: Ryan Charles J. , Rosenthal Mark , Ng Siobhan , Alumkal Joshi , Picus Joel , Gravis Gwenaëlle , Fizazi Karim , Forget Frédéric , Machiels Jean-Pascal , Srinivas Sandy , Zhu Min , Tang Rui , Oliner Kelly S. , Jiang Yizhou , Loh Elwyn , Dubey Sarita , Gerritsen Winald R.
Published: April 2023

PDF file - 1418K, Forest plot of the treatment effect of rilotumumab compared with placebo on OS by covariate subgroups in the intention-to-treat analysis set. ECOG, Eastern Cooperative Oncology Group; PD, progressive disease.
Supplementary Figure S5 from Potent Antimyeloma Activity of a Novel ERK5/CDK Inhibitor
Authors: Álvarez-Fernández Stela , Ortiz-Ruiz María Jesús , Parrott Tracy , Zaknoen Sara , Ocio Enrique M. , San Miguel Jesús , Burrows Francis J. , Esparís-Ogando Azucena , Pandiella Atanasio
Published: April 2023

Effect of TG02 on different parameters associated with apoptosis.
Supplementary Figure S3 from Potent Antimyeloma Activity of a Novel ERK5/CDK Inhibitor
Authors: Álvarez-Fernández Stela , Ortiz-Ruiz María Jesús , Parrott Tracy , Zaknoen Sara , Ocio Enrique M. , San Miguel Jesús , Burrows Francis J. , Esparís-Ogando Azucena , Pandiella Atanasio
Published: April 2023

Survival evaluation of mice treated with TG02 and its combinations with lenalidomide and bortezomib, and weight data corresponding to this in vivo assay.
Live Dead Staining Legend from Antibiotic Treatment Decreases Microbial Burden Associated with Pseudomyxoma Peritonei and Affects β-Catenin Distribution
Authors: Semino-Mora Cristina , Testerman Traci L. , Liu Hui , Whitmire Jeannette M. , Studeman Kimberley , Jia Yali , McAvoy Thomas J. , Francis Jennifer , Nieroda Carol , Sardi Armando , Merrell D. Scott , Dubois Andre
Published: April 2023

Live Dead Staining Legend - PDF file 75K, Legend to Figure S1
Related Article from How to Develop Treatments for Biologically Heterogeneous “Diseases”
Authors: Simon Richard M.
Published: April 2023

Related Article from How to Develop Treatments for Biologically Heterogeneous “Diseases”
Supplementary Table 4 from The Rectal Cancer microRNAome – microRNA Expression in Rectal Cancer and Matched Normal Mucosa
Authors: Gaedcke Jochen , Grade Marian , Camps Jordi , Søkilde Rolf , Kaczkowski Bogumil , Schetter Aaron J. , Difilippantonio Michael J. , Harris Curtis C. , Ghadimi B. Michael , Møller Søren , Beissbarth Tim , Ried Thomas , Litman Thomas
Published: April 2023

XLS file, 36K, Target Prediction.
Supplementary Table 3 from The Rectal Cancer microRNAome – microRNA Expression in Rectal Cancer and Matched Normal Mucosa
Authors: Gaedcke Jochen , Grade Marian , Camps Jordi , Søkilde Rolf , Kaczkowski Bogumil , Schetter Aaron J. , Difilippantonio Michael J. , Harris Curtis C. , Ghadimi B. Michael , Møller Søren , Beissbarth Tim , Ried Thomas , Litman Thomas
Published: April 2023

XLS file, 56K, miRNAs that are differentially expressed between rectal cancer tissue and normal adjacent mucosa.
Supplementary Figure Legend from IDO Expression in Brain Tumors Increases the Recruitment of Regulatory T Cells and Negatively Impacts Survival
Authors: Wainwright Derek A. , Balyasnikova Irina V. , Chang Alan L. , Ahmed Atique U. , Moon Kyung-Sub , Auffinger Brenda , Tobias Alex L. , Han Yu , Lesniak Maciej S.
Published: April 2023

PDF file, 79K.
Supplementary Figure 4 from Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence
Authors: Di Martino Maria T. , Leone Emanuela , Amodio Nicola , Foresta Umberto , Lionetti Marta , Pitari Maria R. , Cantafio Maria E. Gallo , Gullà Annamaria , Conforti Francesco , Morelli Eugenio , Tomaino Vera , Rossi Marco , Negrini Massimo , Ferrarini Manlio , Caraglia Michele , Shammas Masood A. , Munshi Nikhil C. , Anderson Kenneth C. , Neri Antonino , Tagliaferri Pierosandro , Tassone Pierfrancesco
Published: April 2023

PDF file - 108K, Effects induced by stable expression of miR-34a
Supplementary Figures 1 and 2, Table 1 from A Phase I Dose-Finding Trial of Recombinant Interleukin-21 and Rituximab in Relapsed and Refractory Low Grade B-cell Lymphoproliferative Disorders
Authors: Timmerman John M. , Byrd John C. , Andorsky David J. , Yamada Reiko E. , Kramer Janet , Muthusamy Natarajan , Hunder Naomi , Pagel John M.
Published: April 2023

PDF file, 99K, Supplemental Figure 1. Mean rIL-21 serum concentrations after first administration by dose level (μg/kg) versus nominal sampling time. Standard error is represented by whiskers; Supplemental Figure 2. In vivo signaling induced by rIL-21 plus rituximab in circulating lymphoma cells (Patient 1007); Supplemental Table 1. Common Adverse Events by Dose Level.
Supplementary Figure A from Accelerated Tumor Growth Mediated by Sublytic Levels of Antibody-Induced Complement Activation Is Associated with Activation of the PI3K/AKT Survival Pathway
Authors: Wu Xiaohong , Ragupathi Govind , Panageas Katherine , Hong Feng , Livingston Philip O.
Published: April 2023

Supplementary Figure A - PDF file 88K, Cell surface expression of GM2, GD2, and GD3 on CHLA136Luc and Lan-1 (neuroblastoma) and on H524 (SCLC), and CD20 expression on Hs445 and Daudiluc (lymphoma) cell lines. Cell lines were stained by immunofluorescence using appropriate secondary antibodies labeled with FITC. The figure shows histograms of relative fluorescence
Supplementary Table 3 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 71K, Percentage tumor volume compared to control, survival and therapeutic efficacy at days 17 and 38 post-treatment
Supplementary Table 1 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 214K, The EMT signature genes
Supplementary Data from Prediction of Survival following First-Line Chemotherapy in Men with Castration-Resistant Metastatic Prostate Cancer
Authors: Armstrong Andrew J. , Garrett-Mayer Elizabeth , de Wit Ronald , Tannock Ian , Eisenberger Mario
Published: April 2023

Supplementary Data from Prediction of Survival following First-Line Chemotherapy in Men with Castration-Resistant Metastatic Prostate Cancer
Supplementary Table Legend from Analysis of Spontaneous Tumor-Specific CD4 T-cell Immunity in Lung Cancer Using Promiscuous HLA-DR Telomerase-Derived Epitopes: Potential Synergistic Effect with Chemotherapy Response
Authors: Godet Yann , Fabre Elizabeth , Dosset Magalie , Lamuraglia Michele , Levionnois Emeline , Ravel Patrice , Benhamouda Nadine , Cazes Aurélie , Le Pimpec-Barthes Françoise , Gaugler Beatrice , Langlade-Demoyen Pierre , Pivot Xavier , Saas Philippe , Maillère Bernard , Tartour Eric , Borg Christophe , Adotévi Olivier
Published: April 2023

PDF file - 60K
Supplementary Figure 6 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 116K, EMT signature predicts erlotinib sensitivity better than CDH1 or VIM probes. IC50 levels for erlotinib are shown
Supplementary Figure 4 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 109K, EMT signature predicts resistance to EGFR and PI3K inhibitors and greater sensitivity to Axl inhibition
Supplementary Figure 2 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 96K, Structure of pyrrolopyrimidine AXL inhibitor SGI-7079
Supplementary Figure Legends 1-4 from Important Role of Caspase-8 for Chemosensitivity of ALL Cells
Authors: Ehrhardt Harald , Wachter Franziska , Maurer Martina , Stahnke Karsten , Jeremias Irmela
Published: April 2023

PDF file - 59K
Supplementary Figure 1 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
Authors: Byers Lauren Averett , Diao Lixia , Wang Jing , Saintigny Pierre , Girard Luc , Peyton Michael , Shen Li , Fan Youhong , Giri Uma , Tumula Praveen K. , Nilsson Monique B. , Gudikote Jayanthi , Tran Hai , Cardnell Robert J.G. , Bearss David J. , Warner Steven L. , Foulks Jason M. , Kanner Steven B. , Gandhi Varsha , Krett Nancy , Rosen Steven T. , Kim Edward S. , Herbst Roy S. , Blumenschein George R. , Lee J. Jack , Lippman Scott M. , Ang K. Kian , Mills Gordon B. , Hong Waun K. , Weinstein John N. , Wistuba Ignacio I. , Coombes Kevin R. , Minna John D. , Heymach John V.
Published: April 2023

PDF file - 167K, Different probes for the same gene vary within and across microarray platforms
Supplementary Figure 1 from Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non–Small Cell Lung Cancers
Authors: Heller Gerwin , Weinzierl Marlene , Noll Christian , Babinsky Valerie , Ziegler Barbara , Altenberger Corinna , Minichsdorfer Christoph , Lang György , Döme Balazs , End-Pfützenreuter Adelheid , Arns Britt-Madeleine , Grin Yuliya , Klepetko Walter , Zielinski Christoph C. , Zöchbauer-Müller Sabine
Published: April 2023

PDF file - 45K
Supplementary Figure 2 from Combined Alloreactive CTL Cellular Therapy with Prodrug Activator Gene Therapy in a Model of Breast Cancer Metastatic to the Brain
Authors: Hickey Michelle J. , Malone Colin C. , Erickson Kate L. , Lin Amy , Soto Horacio , Ha Edward T. , Kamijima Shuichi , Inagaki Akihito , Takahashi Masamichi , Kato Yuki , Kasahara Noriyuki , Mueller Barbara M. , Kruse Carol A.
Published: April 2023

PDF file - 2858K, Histology of brains from animals exhibiting extended survival from treatment groups 6 and 7 from the experiment shown in Figure 6.
Supplementary Figure 6 from Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
Authors: Engelke Carl G. , Parsels Leslie A. , Qian Yushen , Zhang Qiang , Karnak David , Robertson Jordan R. , Tanska Daria M. , Wei Dongping , Davis Mary A. , Parsels Joshua D. , Zhao Lili , Greenson Joel K. , Lawrence Theodore S. , Maybaum Jonathan , Morgan Meredith A.
Published: April 2023

PDF file, 430K, Jejunal crypt survival following MK8776, gemcitabine, and radiation.
Supplementary Figure 2 from Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776
Authors: Engelke Carl G. , Parsels Leslie A. , Qian Yushen , Zhang Qiang , Karnak David , Robertson Jordan R. , Tanska Daria M. , Wei Dongping , Davis Mary A. , Parsels Joshua D. , Zhao Lili , Greenson Joel K. , Lawrence Theodore S. , Maybaum Jonathan , Morgan Meredith A.
Published: April 2023

PDF file, 340K, MK8776 abrogates the G2 checkpoint in response to gemcitabine/radiation.
Supplementary Table 2 from KRAS and BRAF Mutations Predict Primary Resistance to Imatinib in Gastrointestinal Stromal Tumors
Authors: Miranda Claudia , Nucifora Martina , Molinari Francesca , Conca Elena , Anania Maria Chiara , Bordoni Andrea , Saletti Piercarlo , Mazzucchelli Luca , Pilotti Silvana , Pierotti Marco A. , Tamborini Elena , Greco Angela , Frattini Milo
Published: April 2023

PDF file - 69K, Italian GIST case material.
Data Supplement from Is the “3+3” Dose-Escalation Phase I Clinical Trial Design Suitable for Therapeutic Cancer Vaccine Development? A Recommendation for Alternative Design
Authors: Rahma Osama E. , Gammoh Emily , Simon Richard M. , Khleif Samir N.
Published: April 2023

Supplemental Table 2. Trials that reported correlation of grade 3/4 toxicities and dose level.
Data Supplement from Is the “3+3” Dose-Escalation Phase I Clinical Trial Design Suitable for Therapeutic Cancer Vaccine Development? A Recommendation for Alternative Design
Authors: Rahma Osama E. , Gammoh Emily , Simon Richard M. , Khleif Samir N.
Published: April 2023

Supplemental Table 3. Bacterial vector vaccine trials and their grade 3/4 vaccine-related toxicities.
Figure S2 from Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
Authors: Zannella Vanessa E. , Dal Pra Alan , Muaddi Hala , McKee Trevor D. , Stapleton Shawn , Sykes Jenna , Glicksman Rachel , Chaib Selim , Zamiara Paul , Milosevic Michael , Wouters Bradly G. , Bristow Robert G. , Koritzinsky Marianne
Published: April 2023

PDF file 80K, Figure S2 shows data from in vitro and ex vivo clonogenic assays of metformin treatment in combination with radiation
Supplementary Tables 4 - 8 from Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome
Authors: Wang Zhigang C. , Birkbak Nicolai Juul , Culhane Aedín C. , Drapkin Ronny , Fatima Aquila , Tian Ruiyang , Schwede Matthew , Alsop Kathryn , Daniels Kathryn E. , Piao Huiying , Liu Joyce , Etemadmoghadam Dariush , Miron Alexander , Salvesen Helga B. , Mitchell Gillian , DeFazio Anna , Quackenbush John , Berkowitz Ross S. , Iglehart J. Dirk , Bowtell David D.L. , Matulonis Ursula A.
Published: April 2023

PDF file, 80K, Supplementary Tables 4-8: 4. LOH patterns in three cohorts, 5A&B. FLOH and chemotherapy resistance in three cohorts, 6. BRCA mutations in the AOCS, 7. Univariate and multivariate analysis of platinum resistantce, 8. PFS in LOH subclusters and patients with BRCA mutations.
Supplementary Figure Legends 1-2, Tables 1-6 from NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Authors: Locke Jennifer A. , Zafarana Gaetano , Ishkanian Adrian S. , Milosevic Michael , Thoms John , Have Cherry L. , Malloff Chad A. , Lam Wan L. , Squire Jeremy A. , Pintilie Melania , Sykes Jenna , Ramnarine Varune Rohan , Meng Alice , Ahmed Omer , Jurisica Igor , van der Kwast Theo , Bristow Robert G.
Published: April 2023

Supplementary Figure Legends 1-2, Tables 1-6 from NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Supplementary Figure 2 from Spinophilin Loss Correlates with Poor Patient Prognosis in Advanced Stages of Colon Carcinoma
Authors: Estevez-Garcia Purificacion , Lopez-Calderero Iker , Molina-Pinelo Sonia , Muñoz-Galvan Sandra , Salinas Ana , Gomez-Izquierdo Lourdes , Lucena-Cacace Antonio , Felipe-Abrio Blanca , Paz-Ares Luis , Garcia-Carbonero Rocio , Carnero Amancio
Published: April 2023

PDF file - 58K, Effect of Spn shRNA on human CCR tumor cell lines
Supplementary Figure 7 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 72K, Supplemental Figure 7. Individual chromosome penetrance blots of BRAF-mutant conjunctival melanomas.
Supplementary Figure Legend from Decreased NK Cells in Patients with Head and Neck Cancer Determined in Archival DNA
Authors: Accomando William P. , Wiencke John K. , Houseman E. Andres , Butler Rondi A. , Zheng Shichun , Nelson Heather H. , Kelsey Karl T.
Published: April 2023

PDF file - 83K
Supplementary Figure 5 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 91K, Supplemental Figure 5. Significance of gains and losses calculated using GISTIC 2.0.
Supplementary Figure 4 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 71K, Supplemental Figure 4. Individual chromosome penetrance blots of conjunctival melanomas.
Supplementary Figure 2 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 48K, Supplemental Figure 2. Comparison of array-CGH profiles hybridized using non-amplified and amplified DNA.
Supplementary Figure 10 from Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Authors: Griewank Klaus G. , Westekemper Henrike , Murali Rajmohan , Mach Monika , Schilling Bastian , Wiesner Thomas , Schimming Tobias , Livingstone Elisabeth , Sucker Antje , Grabellus Florian , Metz Claudia , Süsskind Daniela , Hillen Uwe , Speicher Michael R. , Woodman Scott E. , Steuhl Klaus-Peter , Schadendorf Dirk
Published: April 2023

PDF file - 62K, Supplemental Figure 10. Analysis of the GNA11-mutant tumor.
Supplementary Figure 6 from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF File - 80K,
Supplementary Figure 1 from ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Authors: Biddlestone-Thorpe Laura , Sajjad Muhammad , Rosenberg Elizabeth , Beckta Jason M. , Valerie Nicholas C.K. , Tokarz Mary , Adams Bret R. , Wagner Alison F. , Khalil Ashraf , Gilfor Donna , Golding Sarah E. , Deb Sumitra , Temesi David G. , Lau Alan , O'Connor Mark J. , Choe Kevin S. , Parada Luis F. , Lim Sang Kyun , Mukhopadhyay Nitai D. , Valerie Kristoffer
Published: April 2023

PDF File - 571K, Human U1242 glioma cells form highly invasive and aggressive orthotopic tumors in mice.
Supplementary Table 5 from Genetic Profiling Identifies Two Classes of Soft-Tissue Leiomyosarcomas with Distinct Clinical Characteristics
Authors: Italiano Antoine , Lagarde Pauline , Brulard Céline , Terrier Philippe , Laë Marick , Marques Bernard , Ranchere-Vince Dominique , Michels Jean-Jacques , Trassard Martine , Cioffi Angela , Piperno-Neumann Sophie , Chevreau Christine , Blay Jean-Yves , Delcambre Corinne , Isambert Nicolas , Penel Nicolas , Bay Jacques-Olivier , Bonvalot Sylvie , Le Cesne Axel , Coindre Jean-Michel , Chibon Frédéric
Published: April 2023

PDF file - 60K, Biological pathways dysregulated in metastatic LMS
Supplementary Table 1 from Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
Authors: Wakimoto Hiroaki , Tanaka Shota , Curry William T. , Loebel Franziska , Zhao Dan , Tateishi Kensuke , Chen Juxiang , Klofas Lindsay K. , Lelic Nina , Kim James C. , Dias-Santagata Dora , Ellisen Leif W. , Borger Darrell R. , Fendt Sarah-Maria , Vander Heiden Matthew G. , Batchelor Tracy T. , Iafrate A. John , Cahill Daniel P. , Chi Andrew S.
Published: April 2023

PDF file - 85KB, Supplementary Table S1. 2-hydroxyglutarate (2HG) measurements of mouse glioma orthotopic xenografts.
Supplementary Figure 6 from Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant Gliomas
Authors: Wakimoto Hiroaki , Tanaka Shota , Curry William T. , Loebel Franziska , Zhao Dan , Tateishi Kensuke , Chen Juxiang , Klofas Lindsay K. , Lelic Nina , Kim James C. , Dias-Santagata Dora , Ellisen Leif W. , Borger Darrell R. , Fendt Sarah-Maria , Vander Heiden Matthew G. , Batchelor Tracy T. , Iafrate A. John , Cahill Daniel P. , Chi Andrew S.
Published: April 2023

PDF file - 102KB, Supplementary Figure S6. Sphere formation assay of MGG152 expressing N-MYC shRNA.
Supplementary Table 8 from A Signature Predicting Poor Prognosis in Gastric and Ovarian Cancer Represents a Coordinated Macrophage and Stromal Response
Authors: Busuttil Rita A. , George Joshy , Tothill Richard W. , Ioculano Kylie , Kowalczyk Adam , Mitchell Catherine , Lade Stephen , Tan Patrick , Haviv Izhak , Boussioutas Alex
Published: April 2023

XLS file - 21KB, Two way table showing the relationship between AJCC stage and SRC status.
Supplementary Tables 1 - 3 from Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma
Authors: Mydlarz Wojciech , Uemura Mamoru , Ahn Sun , Hennessey Patrick , Chang Steven , Demokan Semra , Sun Wenyue , Shao Chunbo , Bishop Justin , Krosting Julie , Mambo Elizabeth , Westra William , Ha Patrick , Sidransky David , Califano Joseph
Published: April 2023

XLSX file - 15K, Supplementary Table 1. Clinical characteristics of discovery cohort. Supplementary Table 2. Clinical characteristics of mRNA expression array cohort. Supplementary Table 3. Clinical characteristics of validation cohort.
Supplementary Figure Legend from Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma
Authors: Mydlarz Wojciech , Uemura Mamoru , Ahn Sun , Hennessey Patrick , Chang Steven , Demokan Semra , Sun Wenyue , Shao Chunbo , Bishop Justin , Krosting Julie , Mambo Elizabeth , Westra William , Ha Patrick , Sidransky David , Califano Joseph
Published: April 2023

PDF file - 67K
Supplementary Figure Legends from Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363
Authors: Lamoureux Francois , Thomas Christian , Crafter Claire , Kumano Masafumi , Zhang Fan , Davies Barry R. , Gleave Martin E. , Zoubeidi Amina
Published: April 2023

PDF file - 68 KB
Supplementary Figure 3 from COX-2–Independent Effects of Celecoxib Sensitize Lymphoma B Cells to TRAIL-Mediated Apoptosis
Authors: Gallouet Anne-Sophie , Travert Marion , Bresson-Bepoldin Laurence , Guilloton Fabien , Pangault Céline , Caulet-Maugendre Sylvie , Lamy Thierry , Tarte Karin , Guillaudeux Thierry
Published: April 2023

PDF file - 67K, (A) SUDHL4 and BL2 cell lines (105 cells) were cultured on transwell (black bars) or co-cultured with HD-RESTO or HD-RESTO+B cells under transwell (white and grey bars, respectively). After TRAIL treatment (100ng/ml), indirect survival effect of soluble factors produced by stromal cells were evaluated, compared to co-culture without transwell (shaded bars), Mean plus-minus SD, n=5. (B) BL2 and SUDHL4 were cultured with supernatants from HD-RESTO co-cultured or not with B cell lines (white and grey bars respectively) for 24h and treated with or without 100ng/ml TRAIL. These results were compared with B cells co-cultured with HD-RESTO (shaded bars). Mean plus-minus SD, n=4. *p≤0.05, **p less than or equal to0.01 and ***p less than or equal to0.001
Supplementary Figure 2 from Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas
Authors: McCleland Mark L. , Adler Adam S. , Deming Laura , Cosino Ely , Lee Leslie , Blackwood Elizabeth M. , Solon Margaret , Tao Janet , Li Li , Shames David , Jackson Erica , Forrest William F. , Firestein Ron
Published: April 2023

PDF file - 138K, LDHB expression analysis in KRAS mutant cancers versus wildtype colon cancer
Supplementary Table 3 from Tumor-Specific Isoform Switch of the Fibroblast Growth Factor Receptor 2 Underlies the Mesenchymal and Malignant Phenotypes of Clear Cell Renal Cell Carcinomas
Authors: Zhao Qi , Caballero Otavia L. , Davis Ian D. , Jonasch Eric , Tamboli Pheroze , Yung W.K. Alfred , Weinstein John N. , Strausberg Robert L. , Yao Jun
Published: April 2023

XLSX file - 12K, Predicted percentages of samples having FGFR2 IIIc as the major isoform in multiple cancers
Supplementary Text from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

Supplementary Text - PDF file 195K, Supplementary Methods and Figure legends
CCR Translation for This Article from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Authors: Tomita Yusuke , Yuno Akira , Tsukamoto Hirotake , Senju Satoru , Kuroda Yasuhiro , Hirayama Masatoshi , Irie Atsushi , Kawahara Kenta , Yatsuda Junji , Hamada Akinobu , Jono Hirofumi , Yoshida Koji , Tsunoda Takuya , Kohrogi Hirotsugu , Yoshitake Yoshihiro , Nakamura Yusuke , Shinohara Masanori , Nishimura Yasuharu
Published: April 2023

CCR Translation for This Article from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor
Supplementary Figure 4 from Synergistic Antitumor Activity of Cetuximab and Namitecan in Human Squamous Cell Carcinoma Models Relies on Cooperative Inhibition of EGFR Expression and Depends on High EGFR Gene Copy Number
Authors: De Cesare Michelandrea , Lauricella Calogero , Veronese Silvio Marco , Cominetti Denis , Pisano Claudio , Zunino Franco , Zaffaroni Nadia , Zuco Valentina
Published: April 2023

PDF file - 339K, Immunofluorescence analysis of EGFR and c-Cbl distribution in EGF-stimulated A431 cells.
Supplementary Figure 6 from Measles Virus Vaccine–Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells
Authors: Guillerme Jean-Baptiste , Boisgerault Nicolas , Roulois David , Ménager Jérémie , Combredet Chantal , Tangy Frédéric , Fonteneau Jean-François , Gregoire Marc
Published: April 2023

PDF file - 214K, Supplemental Figure 6: Monocyte-derived DC exhibit a similar level of NYESO-1 cross-presentation compared to pDC. (A) on day0, pDC and monocytes from a single donor were purified. pDC were frozen and monocytes cultured with IL-4 and GM-CSF. On day 5, pDC were thawed. pDC and monocyte-dervied DC were cultured alone or with UV-irradiated M18 (M18UV) or MV-infected M18 (M18MV) for 18hrs. On day6, DC were cultured with the NYESO-1 specific CD8+ T cell clone during 6hrs in presence of brefeldinA. Cells were then stained with anti-CD8+ antibody, fixed, permeabilized and stained with IFN-g specific antibody. IFN-g secretion by the the T cell clone was analyzed by flow cytometry. We conclude that level of cross-presentation was somewhat similar between the two cell types. It was a little bit weaker for pDC, but these cells have been frozen, whereas Monocyte-derived DC were not. (B) scatter plot representation of three cross-presentation experiments performed with monocyte-derived DC. Error bars represent standard deviation.
Supplementary Table 1 from Association of RASSF1A and p63 with Poor Recurrence-Free Survival in Node-Negative Stage I–II Non–Small Cell Lung Cancer
Authors: Ko Eunkyung , Lee Bo Bin , Kim Yujin , Lee Eun Ju , Cho Eun Yoon , Han Jungho , Shim Young Mog , Park Joobae , Kim Duk-Hwan
Published: April 2023

PDF file - 140 KB, Primer sequences used for MSP
Supplementary Figure 1 from A Comparative Analysis of Prognostic Factor Models for Follicular Lymphoma Based on a Phase III Trial of CHOP–Rituximab versus CHOP + 131Iodine—Tositumomab
Authors: Press Oliver W. , Unger Joseph M. , Rimsza Lisa M. , Friedberg Jonathan W. , LeBlanc Michael , Czuczman Myron S. , Kaminski Mark , Braziel Rita M. , Spier Catherine , Gopal Ajay K. , Maloney David G. , Cheson Bruce D. , Dakhil Shaker R. , Miller Thomas P. , Fisher Richard I.
Published: April 2023

PDF file 82K, Supplementary Figure 1: Wald Chi Square Analysis Defining Optimal Cutpoints for Lactate Dehydrogenase and Beta 2 Microglobulin Levels for Prognostic Model construction for PFS (S1A) or OS (S1B) for Patients Enrolled on Protocol S0016
Supplementary Figure 2 from The Immune Signature of CD8+CCR7+ T Cells in the Peripheral Circulation Associates with Disease Recurrence in Patients with HNSCC
Authors: Czystowska Malgorzata , Gooding William , Szczepanski Miroslaw J. , Lopez-Abaitero Andres , Ferris Robert L. , Johnson Jonas T. , Whiteside Theresa L.
Published: April 2023

PDF file - 3533 KB, The presence of CD8+CCR7+ T cells in HNSCC in situ
Supplementary Figure 1 from The Immune Signature of CD8+CCR7+ T Cells in the Peripheral Circulation Associates with Disease Recurrence in Patients with HNSCC
Authors: Czystowska Malgorzata , Gooding William , Szczepanski Miroslaw J. , Lopez-Abaitero Andres , Ferris Robert L. , Johnson Jonas T. , Whiteside Theresa L.
Published: April 2023

PDF file - 1978 KB, Decreased percentages of circulating apoptosis-resistant CD8+CCR7+ T cells in HNSCC patients and NC
Supplementary Figure 3 from Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects
Authors: Fransen Marieke F. , van der Sluis Tetje C. , Ossendorp Ferry , Arens Ramon , Melief Cornelis J.M.
Published: April 2023

PDF file - 22K, T regulatory T cells in spleen.
Supplementary Figure 1 from Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects
Authors: Fransen Marieke F. , van der Sluis Tetje C. , Ossendorp Ferry , Arens Ramon , Melief Cornelis J.M.
Published: April 2023

PDF file - 22K, Repeated injections vs single injection.
Supplementary Table 1 from Evaluation of Progression-Free Survival as a Surrogate Endpoint for Survival in Chemotherapy and Targeted Agent Metastatic Colorectal Cancer Trials
Authors: Sidhu Roger , Rong Alan , Dahlberg Steve
Published: April 2023

PDF file - 73 KB, Correlation Between Overall Survival Hazard Ratios and Response Rates
Supplementary Table 1 from Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors
Authors: Zhang Libo , Marrano Paula , Kumar Sushil , Leadley Michael , Elias Evelyn , Thorner Paul , Baruchel Sylvain
Published: April 2023

Supplementary Table 1 - PDF file 55K, Maximum tumor response achieved in rhabdomyosarcoma and neuroblastoma xenograft tumor models
Supplementary Figure 3 from Tumor Suppressive Effects of Bromodomain-Containing Protein 7 (BRD7) in Epithelial Ovarian Carcinoma
Authors: Park Young-Ae , Lee Jeong-Won , Kim Hye-Sun , Lee Yoo-Young , Kim Tae-Joong , Choi Chel Hun , Choi Jung-Joo , Jeon Hye-Kyung , Cho Young Jae , Ryu Ji Yoon , Kim Byoung-Gie , Bae Duk-Soo
Published: April 2023

PDF - 856K, Western blot analysis was used to determine expression levels of alpha-catenin when two ovarian cancer cells were transfected with BRD7 plasmid.
Supplementary Methods, Figure Legends, Tables 1 - 2 from Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature
Authors: Herrera Mercedes , Islam Abul B.M.M.K. , Herrera Alberto , Martín Paloma , García Vanesa , Silva Javier , Garcia Jose M. , Salas Clara , Casal Ignacio , de Herreros Antonio García , Bonilla Félix , Peña Cristina
Published: April 2023

PDF file - 176K, Supplementary Table S1: Sequence of the primer and conditions for the amplification of each gene. Supplementary Table S2: mRNA expression data of IGFBP3, OAS2, MX1 and ROBO2 in a series of 142 colon cancer patients.
Supplementary Table S1 from The Tumor-Suppressive Function of UNC5D and Its Repressed Expression in Renal Cell Carcinoma
Authors: Lu Dan , Dong Dong , Zhou Yu , Lu Min , Pang Xue-Wen , Li Yan , Tian Xiao-Jun , Zhang Yu , Zhang Jun
Published: April 2023

Supplementary Table S1 - PDF file 84K, Supplementary Table S1. Primers and oligonucleotides used in this study