bluuebunny/crossref_metadata_2025 huggingface dataset:
On line bundles arising from the LCK structure over locally conformal Kähler solvmanifolds
Authors: Yamada Takumi
Published: May 2024

We can construct a real line bundle arising from the locally conformal Kähler (LCK) structure over an LCK manifold. We study the properties of this line bundle over an LCK solvmanifold whose complex structure is left-invariant. Mainly, we prove that this line bundle

L

L

over an LCK solvmanifold

Γ
\
G

\Gamma \backslash G

with left-invariant complex structure is flat and

G

G

has a global closed 2-form, which induces an Hermitian structure on the holomorphic tangent bundle twisted by the line bundle

L

C

=
L
⊗
C

{L}^{{\mathbb{C}}}=L\otimes {\mathbb{C}}

if the Lee form is cohomologous to a left-invariant 1-form on

G

G

.
The Heterogeneous Effect and Transmission Paths of Air Pollution on Housing Prices: Evidence from 30 Large- and Medium-Sized Cities in China
Authors: Liu Guangping , Zhang Guo , Li Yanfei , Yu Yang
Published: May 2024

Utilizing panel data from 30 large- and medium-sized cities in China from 2003 to 2018, this study employs the bootstrap method to investigate the heterogeneous impact of air pollution on housing prices and its underlying mechanisms. The research findings indicate that an increase in the concentration of various air pollutants has a restraining effect on housing prices, with the primary components of haze exerting a greater influence. Air pollution indirectly affects housing prices by influencing urban economic development and the development of the tertiary industry, with population density and the development of the secondary industry not serving as mediators in this relationship. Finally, policy recommendations are provided, including enhancing mandatory standards for energy consumption and waste gas emissions by enterprises, establishing a robust environmental monitoring system, and promoting industrial transformation and upgrading, aiming to provide insights for the stable development of the real estate industry.
Synthetic and therapeutic review of triazoles and hybrids
Authors: Goyal Akshi , Bhandari Meena
Published: May 2024

Triazoles act as important pharmacophores in showing biological activity such as antibacterial, antifungal, antitumour/anticancer, anti-inflammatory activities. Literature review suggests that triazoles have been maximally used in carrying research related activities in reference to biological evaluation as compared to other nitrogen containing five membered heterocycles like tetrazoles, pentazoles, pyrazoles, and imidazoles. The first compound of this class was discovered by Janseen Group in 1960s. The microbes act counteractively towards antibiotics which in turn challenge the efficacy of the drugs and thus create room for the progression of more potent avant-garde drugs. Thus, the synthesis of hybrid molecules has been accelerated from last two decades as the hybrids possess more potency, vigour, and adequacy than its constituting pharmacophores. So, this review represents a condensed report of the research carried out in relation to synthetical procedures and assessment of the antibacterial and antifungal activity of triazoles.
Situating Tort Law Within a Web of Institutions: Insights for the Age of Artificial Intelligence
Authors: Martínez Alles María Guadalupe
Published: May 2024

Reasonableness and Risk offers two main claims that might open up fruitful avenues for further reflection. The first claim has to do with the need to abandon form and turn our attention to substance. The argument is that we cannot understand or justify the law of torts without attending to the interests that it protects. The second claim is related to the need to abandon the habit of treating torts in isolation and instead study its integration within a web of institutions which share responsibility for protecting the urgent interests of members of society. The argument here is that our urgent interest in physical integrity exceeds (goes beyond and is greater than) the law of torts. In engaging with these claims, this paper points out potential connections with some pressing questions for both tort law and risk regulation brought to the fore by the recent emergence of Artificial Intelligence (AI) systems.
Focused physicochemical stability study of reconstituted trastuzumab biosimilar SB3 (Ontruzant®) stored in the original vials over 28 days
Authors: Knoll Laura , Thiesen Judith , Krämer Irene
Published: May 2024

Objective

Trastuzumab biosimilar SB3 (Ontruzant®), a HER2 binding monoclonal antibody, is available as powder for concentrate for solution for infusion. According to the summary of product characteristics, the reconstituted solution (21 mg/mL) is physicochemically stable for 7 days when stored refrigerated at 2–8 °C. The objective of this focused study was to determine the extended physicochemical stability of trastuzumab SB3 reconstituted with water for injection and stored in the original glass vials under refrigeration or at room temperature over a period of 28 days.

Methods

Ontruzant® vials were reconstituted with sterile water for injection and stored light protected at 2–8 °C in the refrigerator or at room temperature (15–25 °C, Ph. Eur.) over a maximum period of 28 days. At predefined time points (day 0, 7, 14, (21), 28) samples were withdrawn and analyzed by size-exclusion high-performance liquid chromatography with photodiode array detection, ultraviolet spectroscopy, and pH measurement. Test solutions were inspected for colour changes, clarity, and visible particles at each sampling time point.

Results

According to the size-exclusion chromatography assay, trastuzumab SB3 monomer concentrations exceeded 95 % of the initially measured concentrations over the entire study period. pH values and trastuzumab concentrations measured by UV remained unchanged. No colour changes or visible particles were detected. Results were independent from storage temperature.

Conclusions

According to the stability indicating methods used, physicochemical stability of reconstituted trastuzumab SB3 Ontruzant® solution in original glass vials is given over a period of 28 days either stored refrigerated or at room temperature. Results have to be substantiated by IE-HPLC or icIEF. To avoid microbiological instability storage under refrigeration is recommended.
Cancer-related pain experienced in daily life is difficult to communicate and to manage – for patients and for professionals
Authors: Ikander Tine , Raunkiær Mette , Voetmann Cecilie , Pedersen Caroline V. , Jarlbaek Lene
Published: May 2024

Objectives

The aim of this study was to gain qualitative insight into cancer patients’ experiences, explanations, and management strategies regarding their cancer-related pain (CP).

Methods

Seventeen patients with CP were interviewed using a semi-structured interview approach. Braun and Clarke’s thematic analysis method was used to analyze the transcribed interviews. The patients all participated in cancer rehabilitation courses arranged by the research clinic at The Danish Knowledge Centre for Rehabilitation and Palliative Care.

Results

Three themes were identified: (1) Explaining CP: Patients found it difficult to explain how they experienced their pain. They lacked words, and they frequently used invasive metaphors such as “Pain feels like a heart attack” (2). Strategies and barriers to the management of CP: Initiatives provided by healthcare professionals (HCPs) were perceived as insufficient, and the patients missed guidance in both pharmacological and non-pharmacological approaches to pain management. Several saw medicine as unnatural for their body, and they focused on side effects and the medicine affecting their quality of life. (3) Responsibility for managing CP: A lack of responsiveness from the HCPs and taking on responsibility for pain management were experienced by several of the patients. The patients expressed uncertainty about whom to contact for help with the management of their CP.

Conclusion

The patients’ difficulties in explaining, understanding, and communicating their pain and pain management contributed to insufficient pain management. They were also uncertain about who had the responsibility to help them to achieve pain relief. These results share the evidence drawn from studies on patients with chronic non-cancer pain. This qualitative study highlights the need for having more focus on a common language and shared understanding between patients and HCPs. It also underpins the importance of HCPs to assume their responsibility to help patients manage their pain conditions.
Individual Approaches to the Philosophical Interpretation of Successful Settlements, Their Evaluation
Authors: Slezák-Bartos Zsuzsanna
Published: May 2024

Settlements are complex systems that operate on the basis of many dimensions and aspects and the active participation of local communities, settlement leaders and residents is essential for successful development and ensuring a sustainable futureinfluencing the identity, power relations and community relations of the people living there. The task of local organizations is to help building the community and the support of local initiatives. Public services and infrastructure support the operation ofsettlements and the quality of life of the population, while economic segments such as retail trade, industry and tourism have their highlighted importance in terms of economic development. Settlements are multifaceted entities that are defined not onlyby residences, but also by community life, the economy, the environment and local institutions. Cities are centers of economic activity, where jobs are created, businesses operate and develop. The settlement philosophy can help to create economic structures that are diversified, resistant to crises and support local economic growth. So the importance of the ideas of settlement philosophy and their necessary exmination related to the fact that settlements are the scene of human life, such areas that are environmentally sustainable, socially just and economically prosperous. The leaders of the settlement, residents and local organizations must conduct an open dialogue and strive for cooperation in matters affecting the settlement, thereby ensuring the pursuit of sustainable economic, social and environmental development. The principles of transparency, responsibility, equality and integrity must be respected by all involved participants, but ethical thinking and value-oriented decisions can help the development of settlements and promoting the well-being of the community.
Sympathy and Pride in George Eliot’s Fiction
Authors: Malachuk Daniel S.
Published: May 2024

Daniel S. Malachuk, “Sympathy and Pride in George Eliot’s Fiction” (pp. 32–58)

Sympathy’s undisputed champion, George Eliot, has also long been associated with modern liberalism’s aspiration to inclusion. In her fiction, though, Eliot reaches conclusions more aligned with Rousseau’s Second Discourse: only a balance of sympathy for others with pride in oneself will foster the reciprocal relationships that enable inclusive societies. This essay illuminates Eliot’s unwavering conviction that sympathy and pride must be harmonized as moral motivations in three of her major novels. What did waver, though, was Eliot’s political confidence that liberal states would promote this harmonizing program. If the tragic conflict between Tom’s pride and Maggie’s sympathy in The Mill on the Floss (1860) was optimistically resolved by the harmonious protagonists of Middlemarch (1871–72), Eliot’s political skepticism returns in Daniel Deronda (1876): here, the proudly powerful at best only pretend to sympathize, while the sympathetic are empowered by pride only if they’re lucky. Rousseau’s final lesson to Eliot, then, is his pessimism.
From Discrimination to Dismissal: Navigating Obstacles on the Path to Workplace Justice
Authors: Tomsej Jakub
Published: May 2024

This article explores the challenges faced by employees in the Czech Republic when seeking legal redress in cases of discrimination and unfair dismissal. It emphasizes the importance of accessible legal recourse as a means to rectify individual grievances and reinforce equitable employment practices. In the context of discrimination, the article discusses challenges such as low awareness of anti-discrimination rights and the ancillary nature of sanctions. Recommendations include aligning the Anti-Discrimination Act with the Civil Code, empowering NGOs or the Ombudsman to initiate lawsuits in the public interest, and raising awareness among potential victims. In the section on unfair dismissal, the article outlines the complex process involved in disputing terminations from an employee’s perspective. It discusses obstacles such as complex, costly, and lengthy legal procedures and the requirement for reinstatement. These challenges contribute to the low number of employment lawsuits in the Czech Republic. Recommendations for improvement include enhancing the visibility of court actions, providing free or subsidized legal advice, shifting the focus of lawsuits towards monetary compensation, promoting mediation, and expediting proceedings. The article identifies common challenges in discrimination and unfair dismissal cases in the Czech Republic, highlighting the need for reforms to improve access to justice, reduce financial barriers, expedite legal proceedings, and enhance the dissuasive impact of remedies. These reforms are seen as essential for creating a fair and equitable workplace environment for all employees in the country.
Implementation of Home Parenting Activities as an Effort to Prepare Early Childhood Growth and Development
Authors: Irchamni Achmad , Anwar Sholihul , Utami Daya
Published: May 2024

Parents have an essential role in caring for, educating, and meeting the needs of a child, especially in the aspect of growth and development. How parents educate is very important for the growth and development of early childhood. Education and upbringing at home must be harmonized with education at school so that children grow up to be intelligent, independent, and have character, growing into strong and rugged individuals. This research was motivated by a need for parental awareness of children's learning activities at school, inappropriate parenting patterns, and the importance of children's education. This research aims to determine children's development as a communication tool and the model for implementing learning programs in collaboration with parents in early childhood education, especially in Blora Regency. This research was conducted using a qualitative approach obtained through interviews, documentation data, and observation data regarding the implementation of home parenting programs or activities. This research shows that home parenting activities can be carried out through reporting on children's learning progress at school, knowledge of early detection of growth and development, parents' skills in creating work, and involvement of parents as resource persons. Parenting methods are usually carried out at school and sometimes only once a semester; for home parenting, this is done once a month. Implementing home parenting activities can make it easier for parents to provide parenting lessons and learn more about their children's activities.
Artificial neural network-based computational algorithm of inverse sumudu transform applied to surface transient electromagnetic sounding method
Authors: Эпов М.И. , Даниловский К.Н. , Нечаев О.В. , Михайлов И.В.
Published: May 2024

Рассматриваются результаты разработки нейросетевого алгоритма обратного преобразования Сумуду применительно к задаче наземного нестационарного электромагнитного зондирования. Преобразование Сумуду перспективно для решения прямых задач геоэлектрики в трехмерных моделях сред, поскольку, в отличие от использования преобразования Лапласа или Фурье, Сумуду-изображение действительной функции также является действительной функцией. Таким образом, при последующих вычислениях не возникает необходимости прибегать к комплексным числам, что снижает вычислительные затраты и требования к оперативной памяти в случае успешного определения Сумуду-изображения функции. К недостаткам подхода можно отнести отсутствие явного способа вычисления обратного преобразования. Обращение можно осуществить путем решения соответствующего интегрального уравнения Фредгольма первого рода, однако это является плохо обусловленной задачей и приводит к высоким требованиям к точности получения Сумуду-изображения. Применение современных технологий машинного обучения может обеспечить получение метода, более устойчивого к шуму во входных данных. В работе описывается процесс создания обучающего набора данных и разработки нейросетевого алгоритма, оценивается точность и производительность разработанного решения. Предложенный способ позволит развивать новые подходы к моделированию физических процессов, анализу, обработке и интерпретации измеренных геофизических данных.

The paper discusses the results of the development of a deep learning-based algorithm of the inverse Sumudu transform applied to the problem of on-ground non-stationary electromagnetic sounding. The Sumudu transform has potential for solving forward geoelectric problems in three-dimensional earth models because, unlike using the Laplace or Fourier transform, the Sumudu image of a real function is also a real function. Thus, there is no need to use complex numbers in subsequent calculations, which reduces computational costs and memory requirements in case of successful determination of the Sumudu image of the function. The disadvantages of the approach include the absence of an explicit method for calculating the inverse transform. The inversion can be done by solving the corresponding Fredholm integral equation of the first kind, but this is a poorly conditioned task leading to high requirements for the accuracy of the Sumudu image. The use of modern machine learning techniques can provide a method that is more robust to noise in the input data. This paper describes the process of creating a training dataset and developing a neural network algorithm; we evaluate the accuracy and performance of the obtained solution. The proposed method can contribute to the development of new approaches to physical processes modeling as well as to analysis, processing and interpretation of measured geophysical data.
Structure of the hydrothermal system of thermal fields inferred from geological-geophysical modeling: a case study of the kambalny volcanic ridge (kamchatka)
Authors: Нуждаев И.А. , Рычагов С.Н. , Феофилактов С.О. , Букатов Ю.Ю.
Published: May 2024

На основании комплексных структурно-геофизических исследований и обобщения геофизических, гидрогеологических, минералого-геохимических и других данных показано, что термальные поля южной группы Камбального вулканического хребта (Южная Камчатка) входят в состав современной гид­ротермальной системы. Получены новые данные о строении зоны разгрузки парогидротерм до глубины около 300 м. Установлена структурная и гидродинамическая связь двух термальных полей этой группы. Предполагается единое тепловое питание геотермальной системы Камбального хребта, объединяющей все основные группы термальных полей.

Based on integrated structural and geophysical studies and generalization of geophysical, hydrogeological, mineralogical, geochemical and other data, it is shown that the southern cluster of thermal fields of the Kambalny volcanic ridge (South Kamchatka) is included in the modern hydrothermal system. New data on the structure of the steam hydrotherm discharge area investigated to a depth of about 300 m have been obtained. The structural and hydrodynamic connection between two thermal fields from this group has been established. The Kambalny ridge geothermal system embracing all major clusters of thermal fields is assumed to have a single deep-seated source of heat supply.
The Effect of Calcitonin Gene-Related Peptide Monoclonal Antibodies on Quality of Life among Migraine Patients: Pilot Study at the Hospital of Lithuanian University of Health Sciences Kaunas Clinics
Authors: Remenčiūtė Monika , Varžaitytė Greta , Žemgulytė Gintarė
Published: May 2024

Background: Migraine has a negative impact on patients’ quality of life, with the frequency of attacks being associated with greater disability and poorer health status. Frequent migraine-type headaches require prophylactic treatment, which has so far been of limited effectiveness until advent of calcitonin gene-related peptide (CGRP) monoclonal antibody.Materials and Methods: A prospective analysis was conducted of data from 41 migraine patients who experienced 4 or more monthly migraine days (MMD) longer than three months. At the beginning of the study, treatment with monoclonal antibodies against CGRP (fremanezumab 225 mg or erenumab 70 or 140 g per month) was prescribed according to the indications. The effect of the medications was evaluated after 3-month period.Results: The mean age of patients was 37.17 (±11.78) years. It was found that 17 patients (41.5%) had episodic migraine (EM) and 24 (58.5%) had chronic migraine (CM). Fremanezumab was prescribed to 26 patients (63.4%) and erenumab to 15 patients (36.6%); among the latter, 13 patients used 70 mg/month and 2 patients used 140 mg/month. Three months after treatment, CM changed to EM for 19 patients (79.2%), 27 patients (65.9%) had ≥50% reduction in the number of MMD and total migraine disability assessment (MIDAS) score was reduced by >50% in 31 patients (75.6%). Also, all areas of quality of life of patients were improved after 3 months continued treatment compared to baseline.Conclusions: For more than half the patients using fremanezumab or erenumab after 3-month period, MMD decreased by ≥50% and total MIDAS score by >50 points. All areas of quality of life were improved after prophylactic treatment of migraine.
Survival after Consecutive Myocardial Infarction and Stroke: A Case Report
Authors: Ratautė Kristina , Burneikaitė Greta , Badarienė Jolita
Published: May 2024

Background: Myocardial infarction and stroke are prevalent and potentially fatal urgent medical conditions. Stroke as a subsequent cardiovascular event after the myocardial infarction significantly decreases the odds of survival for the patient.Clinical case: We report a case of a 48-year-old man admitted to Vilnius University Hospital Santaros Klinikos due to an ST-segment elevation myocardial infarction. Patient also experienced a cardioembolic cerebral infarction on the tenth day in the hospital. The patient survived this dual infarction, his general condition improved and he was discharged to the rehabilitation center.Discussion and Conclusions: Cardiovascular diseases are the most common cause of death in the world. Stroke, as a complication of myocardial infarction, affects 0.76–3.2% of patients and demonstrates an increasing incidence trend. In such a dual infarction, in-hospital mortality can be as high as 18–41%. It is hopeful that targeted research and evidence-based prevention with treatment can improve outcomes of concomitant myocardial infarction and stroke.
The Assessment of CDX1, IHH, SHH, GATA4, FOXA2, FOXF1 in Congenital Intra-Abdominal Adhesions
Authors: Freijere Pope Helēna , Pilmane Māra , Junga Anna , Pētersons Aigars
Published: May 2024

Congenital abdominal adhesions are a rare condition that can result in a small bowel obstruction at any age, more frequently in pediatric populations. The cause remains unknown, and the importance of aberrant congenital bands is related to the difficulty of diagnosis, and cases of death with late detection have been documented. This research examines the expression of Caudal Type Homeobox 1 (CDX1), Indian Hedgehog (IHH), Sonic Hedgehog (SHH), GATA Binding Protein 4 (GATA4), Forkhead Box A2 (FOXA2) and Forkhead Box F1 (FOXF1) gene expression in human abdominal congenital adhesion fibroblast and endothelium cells by chromogenic in situ hybridization, with the aim of elucidating their potential association with the etiology of congenital intra-abdominal adhesion band development. The potential genes’ signals were examined using a semi-quantitative approach. Significant correlations were observed between the expression of CDX1 (p <.001) and SHH (p=0.032) genes in fibroblasts from congenital intra-abdominal adhesions compared to fibroblasts from control peritoneal tissue. Statistically significant very strong correlations were found between the CDX1 and IHH comparing endothelium and fibroblast cells in congenital abdominal adhesion bands. There was no statistically significant difference found in the distribution of IHH, FOXA2, GATA4, and FOXF1 between the fibroblasts and endothelium of the patients compared to the control group. The presence of notable distinctions and diverse associations suggests the potential involvement of numerous morpho-pathogenetic processes in the development of intraabdominal adhesions.
The role of Easy Language awareness for Social Inclusion in Latvia, Lithuania, and Slovenia
Authors: Anča Gunta , Bružaitė-Liseckienė Justina , Daraškienė Inga , Haramija Dragica , Lebedytė Undzėnienė Ramunė , Lesjak Saša , Meļņika Irīna , Motiekaitytė Kotryna , Kalnberzina Vita , Kalniņa Maija , Knapp Tatjana , Polinska Velga
Published: May 2024

Easy Language serves as a communication tool designed for use by a broad spectrum of individuals within our society. Like any tool, it requires development, adjustment, and application standards. Some of these standards are common across languages and societies, while others are unique to specific languages, groups of people, or needs. This implies that language users, developers, and researchers can benefit from cooperation but also need to develop their own language- and situation-specific tools and standards of communication.The aim of this research is to compare the change in Easy Language awareness from 2021 to 2022 among societies in Latvia, Lithuania, and Slovenia within a year, using such tools as surveys, in-depth interviews, and statistical analysis. The findings suggest that awareness levels vary across different countries and social groups. Furthermore, it takes more than two years to reach the levels of legal structures and political readiness necessary to embrace the needs of the entire society.
EU Sustainability Quest: Possibilities of Consumer Sales
Authors: Selvestravičiūtė Agnė
Published: May 2024

This paper analyses principal incoherence left in EU rules applicable to consumer sales against the background of the European Commission’s sustainability quest, supposedly influencing every area of the Union’s future life, and argues for a possible need for changes in contemporary consumer law in order to achieve a greater environmental good. It covers three key aspects where the Consumer Sales Directive might have done a better job in addressing environmental worries (i. e. legal guarantee term, assessment of remedies, and commercial guarantees), and states that these aspects were not modified to benefit the environment. The article then covers a deeper problem of conflicting aims that cannot be simultaneously upheld (i. e. fostering and curbing consumption at the same time), and challenges that in order to address environmental problems serious reconsiderations of consumer protection might be necessary.
New concept of etiopathogenesis and treatment of keratoconus (analytical study)
Authors: Oksana Rudkovska
Published: May 2024

There is no single theory of the etiopathogenesis of keratoconus, which creates a serious problem for the prevention and treatment of this disease.
An appraisal of tree and fauna species diversity and distribution of Osogbo sacred grove, Osun State, Nigeria
Authors: JA Ugbe , ED Kuje
Published: May 2024

Appraisal of tree and fauna species is crucial; this ensures effective conservation of the forests and their resources. This study aims at an appraisal of tree and fauna species diversity in Osun-Osogbo Sacred Grove, Nigeria for record update, knowledge, and monitoring species status for conservation management. A total of 70 tree species belonging to 26 families were recorded. The tree species in the Fabaceae and Apocynaceae families were the most abundant. Tree species richness indices for the three zones were 2.16, 1.89, and 1.72, respectively. Most of the tree species encountered were in the IUCN categories of vulnerable (6.7%), least concerning (71.1%), and not evaluated (71.1%). The result revealed that the core zone was richer and more diverse than the buffer and the outer zones, with diversity indices of 3.06, 2.995, and 2.16, respectively. The fauna species diversity and richness index were 3.40 and 2.35, respectively. The least vulnerable fauna species were 86.4%, with 6.8% vulnerable. Class Aves has the highest percentage of 61.4%, with Gastropoda being the least-represented (2.3%). Mona monkeys were the most sighted fauna species in the area. Thus, there is an urgent need to increase the level of security around the sacred grove and to ensure sustainable management strategies are fully implemented in the study area.
Adipokines in rheumatoid arthritis patients suffering glomerulonephritis
Authors: Fayed Ahmed , Hegazy Mohamed Tharwat , Abdulazim Dina O , Ibrahim Moustafa , El Din Usama A Sharaf
Published: May 2024

Background: Beside their eminent role in metabolic syndrome, white adipose tissue (WAT) derived adipokines might have a distinguished role in autoimmune and rheumatic diseases. In addition, increased level of many adipokines is observed in patients suffering glomerulonephritis. The status of adipokines was not studied in rheumatoid arthritis patients (RA) suffering glomerulonephritis (GN). Objective: To study serum level of adiponectin, leptin, and Visfatin in RA patients suffering GN in a trial to elucidate if they play a role on metabolic or endothelial function. Cases and methods: In this cross-sectional case control observational study, we compared serum level of adiponectin, leptin, and Visfatin in fifty RA patients (group I) in coparison to fifty RA cases suffering chronic GN (group II) and fifty normal control subjects. In addition, we looked for kidney function tests and 24 urine protein (UP), serum calcium, phosphorus, alkaline phosphatase (AP), 25 hydroxy vitamin D (25 OH vit. D), parathyroid hormone (PTH), C-reactive protein (CRP), interleukin 6(IL6), lipid profile, and Homa insulin resistanc (Homa IR). RA cases were further investigated for rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) carotid arteries intima media thickness (IMT), brachial artery flow mediated Dilation (BA-FMD), health assessment questionnaire (HAQ), disease activity score calculator (DASC), simple disease activity index (SDAI), and clinical disease activity index (CDAI). Percutaneous kidney biopsies were obtained in group II patients. Results: Serum adiponectin and Visfatin are significantly higher and serum leptin is significantly lower in Group II compared to group I and the control group (20.3 vs. 18.6 and 12.3, 24,5 vs. 20.9 and 9.8, and 3.6 vs. 4.6 and 7.8 ng/mL for median serum adiponectin, visfatin, and leptin in group II vs group I and control group respectively, P<0.001 in all). Serum level of 25 (OH) vit D is significantly lower, while serum AP, PTH and Homa IR are significantly higher in group I compared to control subjects (18 vs. 37 ng/mL, 140.5 vs, 57 u/L, 63 vs 47.8 ng/mL, and 13.2 vs 4 respectively, P<0.001 in all) whilst there is no significant difference in these parameters between the RA groups. BA-FMD is significantly lower in group II vs group I (3% vs 4%, P=0.02) but there are no significant differences between these two groups in IMT of carotid arteries, HAQ, DASC, SDAI or CDAI. Moreover, there is no difference in any of the studied parameters within patients of group II according to renal histopathology. Conclusion: Studied adipokines have no relation to metabolic or vascular complications of RA. Changes of serum adipokines in GN patients are unrelated to inflammation. This pilot study would stimulate further research looking for the possible role of different adipokines in GN complicating RA.
O PLURALISMO TEOLÓGICO CRISTÃO NA ÁFRICA
Authors: Armando Vicente José
Published: May 2024

O Cristianismo que os missionários transmitiram na África não foi destilado e purificado. Durante um longo período, era forçoso que houvesse um diálogo entre o modo de entender as coisas do povo e o que foi introduzido pelos missionários. A questão, portanto, entre o Cristianismo, os hábitos e a prática africanos na vida quotidiana, é +perene nas esferas da Igreja. Esse assunto raras vezes foi encarado como uma questão teológica. Parece que até missionários liberais, que entenderam e ensinaram que a aceitação do Cristianismo por africanos não significa que eles deixem de ser africanos, nunca previram o surgimento de um pensamento africano que iria rejeitar o modelo ocidental de entendimento e percepção, ao mesmo tempo em que reivindicaria ser totalmente cristão.
Alejandro GONZÁLEZ-VARAS IBÁÑEZ, Ideologías y creencias en la formación del Derecho en un contexto global, Ediciones Olejnik, Santiago de Chile 2023, 145 pp., ISBN 978-956-407-363-7
Authors: Ciáurriz María-José
Published: May 2024

Book Review
Protopia jako narracja i praktyka innowacyjności miejskiej w czasach kryzysów
Authors: Laska Artur
Published: May 2024

Celem artykułu jest zaprezentowanie głównych założeń protopii, jako narracji i praktyki politycznej w skali miejskiej. Autor prezentuje argumenty wskazujące na potencjalną efektywność tej koncepcji wdrażania innowacji publicznych, od których dyfuzji zależy rozwiązanie nakładających się kryzysów miejskich, będących przejawem wyzwań globalnych. Zaproponowana interpretacja oparta jest na tzw. integralnej teorii polityki, ale odnosi się także do empirycznych przejawów zjawiska w realiach polskich.
Dyscyplina pracy w wybranych polskich organizacjach – problemy karania w opinii pracowników
Authors: Pokrzywa Magdalena
Published: May 2024

Celem artykułu jest ukazanie opinii pracowników wybranych polskich organizacji na temat dyscypliny, ze szczególnym uwzględnieniem problematyki karania. W artykule skoncentrowano się na opiniach badanych dotyczących częstotliwości karania, dominujących form karania, najczęstszych kar nieformalnych stosowanych w organizacjach zatrudniających badanych oraz emocji towarzyszących respondentom w sytuacji podlegania karze. Badania zrealizowano za pomocą techniki CAWI z 393 pracownikami reprezentującymi różne organizacje w Polsce. Respondenci deklarowali, że na ogół kary formalne stosowane są bardzo rzadko, jednak kary nieformalne występują w większości organizacji zatrudniających badanych. W wyniku stosowania kar następuje najczęściej spadek motywacji do pracy oraz brak satysfakcji z pracy. Karom  towarzyszyło również poczucie niesprawiedliwości.
Potencjał akademicki Katowic i Górnośląsko-Zagłębiowskiej Metropolii. Społeczna percepcja i instytucjonalne uwarunkowania
Authors: Bierwiaczonek Krzysztof , Pyka Robert
Published: May 2024

W artykule podjęto tematykę odnoszącą się do analizy potencjału akademickiego Katowic i Górnośląsko-Zagłębiowskiej Metropolii. Kontekst teoretyczny stanowiły pojęcia miasta akademickiego i metropolii. W pracy postawiono tezę o dyspersji zasobów akademickich występujących w Górnośląsko-Zagłębiowskiej Metropolii. Zjawisko to wynika z policentrycznego charakteru konurbacji katowickiej i braku działań ukierunkowanych na wykorzystanie obecności studentów i pracowników akademickich w gminach tworzących GZM. W artykule wykorzystano wybrane ilościowe wskaźniki potencjału akademickiego oraz dane jakościowe i ilościowe pochodzące z badań i opracowań autorskich. Wskazały one na próby przezwyciężenia zdiagnozowanej dyspersji zasobów akademickich i wzmocnienia współpracy w trójkącie: uczelnie wyższe - miasto Katowice - Górnośląsko-Zagłębiowska Metropolia. Efektem takiej współpracy jest tytuł Europejskiego Miasta Nauki 2024, jakie otrzymało miasto Katowice.
Editorial: Laity in Christian work and witness
Authors: Toth Lina
Published: May 2024

For this issue of the journal, contributions were invited on any subject relevant to the Church and theology in Scotland. From the diverse range of topics covered in the papers selected for the issue, one uniting theme emerged: the significance of the role of lay people in Christian work and witness and in the life of the Church.
"Plato of Athens: A Life in Philosophy" by Robin Waterfield
Authors: Parham Karen
Published: May 2024

Review ofRobin Waterfield, Plato of Athens: A Life in Philosophy (Oxford: OUP, 2023), pp. xxxix + 255, ISBN 978-0197564752. £21.99
Information security narrative for cultural scientists, theorists and cultural workers
Authors: Bylevskiy Pavel
Published: May 2024

The purpose of the study is to determine the role, possibilities and theoretical principles of participation of cultural scientists, theorists and cultural workers in the development and implementation of measures to counter threats associated with the use of computer technologies and Internet communications. The subject of the study is the cultural narrative of scientific publications on information security in 2021–2023. The object of the study is the current risks to traditional values and identity caused by universal digital transformation and, after the start of a Special military operation in Ukraine in 2022, the aggravation of international relations with technologically leading countries and global Internet services based in the United States. The relevance of the topic is determined, in particular, by the approval by the Russian Government on December 22, 2022 of the «Concept of formation and development of the culture of information security of citizens of the Russian Federation». The research methodology is characterized by the application of a cultural paradigm (an approach to the culture of information security as a dynamic system of human activity), structural, functional and evolutionary methods. Publications in the journals HAC K1, K2 and Scopus Q1, Q2 were used as materials.
The novelty of the article lies in the study of the potential of the cultural narrative of information security in solving the problem of forming a general civil culture of information security, professional and mass. The research was carried out within the framework of the state assignment of the Moscow State Pedagogical University on the topic of research «Cultural identity in the modern world: analytical models, methods of construction and forms of presentation» (state registration number
AAAA-A19-119072590048-4). The result of the study is a conclusion about the increasing share and importance of socio-cultural factors in information security in comparison with technical ones. Cultural theory and cultural studies are defined as specialized disciplines for improving both professional and civil information security culture. The cultural paradigm of information security includes a system of interaction between the profile specialization of professional and general civil, mass culture of information security. The effectiveness of the creation of specialized training for cultural scientists, theorists and cultural workers in the field of professional and mass information security culture is predicted and proved.
Features of the construction information classifier adaptation for the classifying of the building information model elements
Authors: Losev Konstantin , Chaplygin Evgeniy
Published: May 2024

The domain area of the article is life cycle management of the construction facilities, where the subject of consideration is the study of digital information models element classification, begun in previous works of the authors, which is part of the thesis. The object of the study is a construction information classifier integrated into the Russian Federation urban planning state information system. The purpose of the article is to analyze the features of the construction information classifier adaptation, as well as to demonstrate its impact on improving the efficiency and accuracy of classification on the base of approbation on a real capital construction object. The expected result is the simplification of the classification process, by automating routine and cyclic processes, which will lead to a labor costs reduction, as well as an overall improvement in information modeling technologies integration and accuracy. As a result of the method modernization described in the previously paper, the tables «Functional Systems» and «Technical Systems» were merged, the first level in the table «Technical Systems» was eliminated, as it serves as information generalization entered in the second level and can be replaced by the second level of the table «Functional System». A multi-level hierarchical table was created, with a structure ranging from two to four levels, providing flexibility and usability. The main conclusion of the article is that the proposed improved classification method based on combining the tables «Functional Systems» and «Technical Systems» of the construction information classifier more than halves the time spent on digital information model elements classifying, and also contributes to better interaction between the investment and construction project participants, increasing the accuracy and quality of work with the model. The authors also conclude that unification and standardization of classification systems (classifiers) taking into account modern requirements and trends in the construction industry are key factors for achieving a high degree of interoperability and efficiency in information modeling.
EFFECT OF BIO-INSPIRED MODIFICATION ON FLUID-STRUCTURE INTERACTION AND ITS CONTROL: A REVIEW
Authors: Sharma Vikas , Dutta Sushanta
Published: May 2024

Bio-inspired surfaces have been a relevant field of study in recent years. This review aims to synthesize
and evaluate the research on passive and active modifications to help develop a new approach to work in
this area and stimulate further research. The review elaborates on flow interactions with control structures
such as riblets, flexible geometry, and synthetic jets for practical applications. Experiments have
confirmed that minor alterations in the near-wall region could affect the wall shear drag produced by
the boundary layer. Biomimetic riblets have shown a significant amount of drag reduction. A review of
the performance studies of riblets is discussed, along with the effect of geometric and flow parameters.
In addition, the flow dynamics involved in flexible structure for thrust generation could be understood
from this review. Active control analysis using synthetic jet actuators has shown potential promise in
aerodynamic applications. The literature indicates that understanding the leading edge vortex (LEV)
is essential for natural fliers study. Alteration of LEV on a flapping wing using active control techniques
has also been summarized.
Instrumentos utilizados en orientación vocacional-profesional una revisión sistemática de tema
Authors:   Universidad de Manizales, Castaño Acosta Steeventh , Tobón Vásquez Gloria del Carmen ,   Universidad de Manizales, Delgado-Reyes Andrés Camilo ,   Universidad de Manizales, Aguirre Aldana Lorena ,   Universidad de Manizales
Published: May 2024

La orientación vocacional puede entenderse como un proceso que ayuda a la elección de una profesión y la preparación para esta, el acceso a su ejercicio, la evolución y progreso posterior. El objetivo de la presente revi-sión de tema es indagar cuáles fueron los instrumentos más utilizados a nivel nacional e internacional a la hora de realizar un proceso de orientación vocacional entre 2015 y 2020 en estudiantes de educación secundaria. Se realizó una búsqueda de artículos derivados de investigaciones en bases de datos como Ebscohost, Science Direct, Scopus, Lilacs, Scielo y Redalyc. En la indagación inicial se registraron 1298 artículos y a partir de los criterios de exclusión, se seleccionaron un total de 23 publicaciones. El análisis realizado conduce a identificar los instrumentos utilizados en los últimos cinco años, en donde el SDS es el instrumento con más frecuencia de uso; esto se debe a la universalidad en su estructura factorial. Conocer los instrumentos empleados a nivel nacional e internacional permitirá implementar herramientas que faciliten realizar procesos de orientación vocacional-profesional más acertados y acordes a las necesidades culturales, actualmente en Colombia presenta déficit de instrumentos estandarizados y válidos para los procesos orientación vocacional.
Abono orgánico: aprovechamiento de los residuos orgánicos agroindustriales
Authors:   Universidad Santo Tomás, Álvarez-Palomino Laura , Vargas-Bayona Javier Enrique ,   Universidad Santo Tomás, García-Díaz Leidy K. ,   Universidad Santo Tomás
Published: May 2024

Tema y alcance: las actividades agropecuarias a nivel mundial, generan gran cantidad de residuos orgánicos que en general no reciben un adecuado pro-ceso y tratamiento de disposición final, y ocasionan contaminación y degradación del medio ambiente. Una alternativa en crecimiento es su transformación para obtener nuevos productos, como los abonos orgánicos. Características: se realizó una revisión sistemática de literatura, en 150 publicaciones entre libros, artículos científicos y bases de datos SciELO, Scopus y ScienceDirect, comprendidos entre 2000 y 2017. Fueron seleccionadas 55 referencias para el análisis teniendo como criterio su utilidad y relevancia en términos del aprovechamiento, transformación y uso de residuos orgánicos, utilizables cómo abono orgánico. Se consideró la soli-dez interna y externa de los artículos incluidos. Hallazgos: se encontró, principal-mente, que los procesos de fermentación como el compostaje y el bocashi resultan alternativas sustentables y sostenibles para la elaboración de abono orgánico, a partir de residuos agroindustriales de origen animal y vegetal. Su impacto mayor ocurre sobre el componente suelo, que recibe macro y micronutrientes y mejoran sus propiedades físicas, químicas, biológicas; con el consecuente mejoramiento del suelo y en la productividad y salud de los cultivos. Conclusiones: se encontró que el compostaje y la elaboración de bocashi son los métodos más frecuentemente utilizados para la obtención de abonos orgánicos, con impacto sobre la agricultura, principalmente por su acción en términos de la incorporación de materia orgánica a los suelos, la corrección de carencias nutricionales, y la potencialización de sus cualidades para los cultivos.
Mesenteric ishemia: features of different methods of diagnosis and treatment
Authors: Kostenko N. V. , Isaeva V. Yu. , Kushalakov A. M. , Mustafaev Z. I. , Yanpol'skiy A. S.
Published: May 2024

Nowadays manifestation of atherosclerosis of mesenteric vessels increases with the growth of cardiovascular pathology. The actual problems of the chronic and acute mesenteric ischemia, its diagnosis and treatment effectiveness were analyzed and considered on the basis of a literature review. Etiopathogenesis, clinical manifestations, diagnostic approaches, treatment strategies including conservative and surgical treatment were considered in this article. The absence of common programs of diagnosis and treatment directs scientific and clinical search with using modern material and technical possibilities.