bluuebunny/crossref_metadata_2025 huggingface dataset:
The Importance of Lung Ultrasound and IGFBP7 (Insulin-like Growth Factor Binding Protein 7) Assessment in Diagnosing Patients with Heart Failure
Authors: Szyszkowska Anna , Olesiewicz Tomasz , Płońska-Korabiewska Izabela , Tarasiuk Ewa , Olesiewicz Barbara , Knapp Małgorzata , Śledziewski Rafał , Sobkowicz Bożena , Lisowska Anna
Published: April 2024

Background: In daily practice, there are problems with adequately diagnosing the cause of dyspnea in patients with heart failure with preserved and mildly reduced ejection fractions (HFpEF and HFmrEF). This study aimed to assess the usefulness of lung ultrasound in diagnosing HFpEF and HFmrEF and determine its correlation with IGFBP7 (insulin-like growth factor binding protein 7), NTproBNP (N-terminal pro–B-type natriuretic peptide), and echocardiographic markers. Methods: The research was conducted on 143 patients hospitalized between 2018 and 2020, admitted due to dyspnea, and diagnosed with HFpEF and HFmrEF. Venous blood was collected from all participants to obtain basic biochemical parameters, NTproBNP, and IGFBP7. Moreover, all participants underwent echocardiography and transthoracic lung ultrasound. Two years after hospitalization a follow-up telephone visit was performed. Results: The number of B-lines in the LUS ≥ 16 was determined with a sensitivity of—73% and specificity of—62%, indicating exacerbation of heart failure symptoms on admission. The number of B-lines ≥ 14 on admission was determined as a cut-off point, indicating an increased risk of death during the 2-year follow-up period. The factors that significantly impacted mortality in the study patient population were age and the difference between the number of B-lines on ultrasound at admission and at hospital discharge. IGFBP7 levels had no significant effect on the duration of hospitalization, risk of rehospitalization, or mortality during follow-up. Conclusions: Lung ultrasonography provides additional diagnostic value in patients with HFpEF or HFmrEF and exacerbation of heart failure symptoms. The number of B-lines ≥ 14 may indicate an increased risk of death.
Clinical and Genetic Correlation in Neurocristopathies: Bridging a Precision Medicine Gap
Authors: Chatzi Despoina , Kyriakoudi Stella Aikaterini , Dermitzakis Iasonas , Manthou Maria Eleni , Meditskou Soultana , Theotokis Paschalis
Published: April 2024

Neurocristopathies (NCPs) encompass a spectrum of disorders arising from issues during the formation and migration of neural crest cells (NCCs). NCCs undergo epithelial–mesenchymal transition (EMT) and upon key developmental gene deregulation, fetuses and neonates are prone to exhibit diverse manifestations depending on the affected area. These conditions are generally rare and often have a genetic basis, with many following Mendelian inheritance patterns, thus making them perfect candidates for precision medicine. Examples include cranial NCPs, like Goldenhar syndrome and Axenfeld–Rieger syndrome; cardiac–vagal NCPs, such as DiGeorge syndrome; truncal NCPs, like congenital central hypoventilation syndrome and Waardenburg syndrome; and enteric NCPs, such as Hirschsprung disease. Additionally, NCCs’ migratory and differentiating nature makes their derivatives prone to tumors, with various cancer types categorized based on their NCC origin. Representative examples include schwannomas and pheochromocytomas. This review summarizes current knowledge of diseases arising from defects in NCCs’ specification and highlights the potential of precision medicine to remedy a clinical phenotype by targeting the genotype, particularly important given that those affected are primarily infants and young children.
Effects of Transcutaneous Electrical Nerve Stimulation with Taping on Wrist Spasticity, Strength, and Upper Extremity Function in Patients with Stroke: A Randomized Control Trial
Authors: Jung Kyoung-sim , Jung Jin-hwa , Cho Hwi-young , In Tae-sung
Published: April 2024

Objective: Six months after the onset of stroke, over 60% of patients experience upper limb dysfunction, with spasticity being a major contributor alongside muscle weakness. This study investigated the effect of transcutaneous electrical nerve stimulation (TENS) with taping on wrist spasticity, strength, and upper extremity function in patients with stroke. Methods: In total, 40 patients with stroke were included and randomly divided into two groups: the TENS + taping (n = 20, age 52.4 ± 9.3 (range: 39 to 70)) and TENS (n = 20, age 53.5 ± 10.8 (range: 39 to 74)) groups. All subjects performed 30 sessions of task-related training, which included 10 min of postural control training and 20 min of task performance. Additionally, all subjects received TENS on the spastic muscle belly for 30 min before task-related training. In the TENS + taping group, taping was additionally applied to the forearm and wrist but not in the TENS group. The Modified Ashworth Scale was used to measure spasticity, and a handheld dynamometer was used to measure muscle strength. The Fugl–Meyer Assessment of Upper Extremity was used to evaluate the functional ability of the upper extremity. Results: In the TENS + taping group, spasticity and upper extremity function were significantly improved as compared to those in the TENS group (p < 0.05). However, no significant difference in muscle strength was observed between the two groups (p > 0.05). Conclusions: This study demonstrated that the combination of TENS and taping for spasticity and function of the upper extremity was more effective in relieving the spasticity than TENS alone. Therefore, we suggest this combination as an additional treatment for spasticity and function of the upper extremity.
Retinal Vessel Analysis and Microvascular Abnormalities in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms
Authors: Roszkowska Anna Maria , Leanza Rossana , Aragona Emanuela , Gargiulo Ludovica , Alibrandi Angela , Arrigo Alessandro , Bottaro Adele , Barone Paola , Stagno Fabio , Allegra Alessandro
Published: April 2024

Background: Philadelphia-negative chronic myeloproliferative neoplasms are a group of clonal hematopoietic disorders including polycythemia vera, essential thrombocythemia, and primary myelofi-brosis. These neoplasms are characterized by an increased risk of thrombotic complications. Several studies have highlighted that the study of vessels of the retina offers the opportunity to visualize, in vivo, the damage to microcirculation that is common in various systemic pathologies. Methods: in our study, forty patients underwent an ophthalmological examination, using non-invasive imaging tech-niques, for analyses of their retinal vascularization. The objective was to correlate the findings ob-tained from this study of the retina with different markers of thrombotic risk, to demonstrate the usefulness of studying retinal vessels as a possible new prognostic biomarker of thrombotic risk in patients affected by Philadelphia-negative chronic myeloproliferative neoplasms. Results: retinal imaging demonstrated changes in the microcirculation, with a reduced vascular density of the deep and superficial capillary plexuses with respect to a normal group, and a correlation between retinal changes and blood parameters. Conclusions: additional research will allow us to determine whether retinal changes in individuals with chronic myeloproliferative neoplasms could be predictive of the development of thrombotic events in these subjects.
Investigating Potential Correlations between Calcium Metabolism Biomarkers and Periprocedural Clinical Events in Major Cardiovascular Surgeries: An Exploratory Study
Authors: Ștef Adrian , Bodolea Constantin , Bocșan Ioana Corina , Vesa Ștefan Cristian , Pop Raluca Maria , Cainap Simona Sorana , Achim Alexandru , Antal Oana , Tintiuc Nadina , Buzoianu Anca Dana
Published: April 2024

Background: There is emerging but conflicting evidence regarding the association between calcium biomarkers, more specifically ionized calcium and the prognosis of intensive care unit (ICU) postoperative cardiac patients. Methods: Our study investigated the relationship between ionized calcium, vitamin D, and periprocedural clinical events such as cardiac, neurologic and renal complications, major bleeding, vasoactive–inotropic score (VIS), and length of ICU and hospitalization. Results: Our study included 83 consecutive subjects undergoing elective major cardiac surgery requiring cardiopulmonary bypass. The mean age of the participants was 64.9 ± 8.5 years. The majority of procedures comprised isolated CABG (N = 26, 31.3%), aortic valve procedures (N = 26, 31.3%), and mitral valve procedures (N = 12, 14.5%). A difference in calcium levels across all time points (p < 0.001) was observed, with preoperative calcium being directly associated with intraoperative VIS (r = 0.26, p = 0.016). On day 1, calcium levels were inversely associated with the duration of mechanical ventilation (r = −0.30, p = 0.007) and the length of hospital stay (r = −0.22, p = 0.049). At discharge, calcium was inversely associated with length of hospital stay (r = −0.22, p = 0.044). All calcium levels tended to be lower in those who died during the 1-year follow-up (p = 0.054). Preoperative vitamin D levels were significantly higher in those who experienced AKI during hospitalization (median 17.5, IQR 14.5–17.7, versus median 15.3, IQR 15.6–20.5, p = 0.048) Conclusion: Fluctuations in calcium levels and vitamin D may be associated with the clinical course of patients undergoing cardiac surgery. In our study, hypocalcemic patients exhibited a greater severity of illness, as evidenced by elevated VIS scores, and experienced prolonged mechanical ventilation time and hospital stays. Additional larger-scale studies are required to gain a deeper understanding of their impact on cardiac performance and the process of weaning from cardiopulmonary bypass, as well as to distinguish between causal and associative relationships.
Virtual Hemodynamic Assessment of Coronary Lesions: The Advent of Functional Angiography and Coronary Imaging
Authors: Nikopoulos Sotirios , Papafaklis Michail I. , Tsompou Panagiota , Sakellarios Antonis , Siogkas Panagiotis , Sioros Spyros , Fotiadis Dimitrios I. , Katsouras Christos S. , Naka Katerina K. , Nikas Dimitrios , Michalis Lampros
Published: April 2024

The fractional flow reserve (FFR) is well recognized as a gold standard measure for the estimation of functional coronary stenosis. Technological progressions in image processing have empowered the reconstruction of three-dimensional models of the coronary arteries via both non-invasive and invasive imaging modalities. The application of computational fluid dynamics (CFD) techniques to coronary 3D anatomical models allows the virtual evaluation of the hemodynamic significance of a coronary lesion with high diagnostic accuracy. Methods: Search of the bibliographic database for articles published from 2011 to 2023 using the following search terms: invasive FFR and non-invasive FFR. Pooled analysis of the sensitivity and specificity, with the corresponding confidence intervals from 32% to 94%. In addition, the summary processing times were determined. Results: In total, 24 studies published between 2011 and 2023 were included, with a total of 13,591 patients and 3345 vessels. The diagnostic accuracy of the invasive and non-invasive techniques at the per-patient level was 89% (95% CI, 85–92%) and 76% (95% CI, 61–80%), respectively, while on the per-vessel basis, it was 92% (95% CI, 82–88%) and 81% (95% CI, 75–87%), respectively. Conclusion: These opportunities providing hemodynamic information based on anatomy have given rise to a new era of functional angiography and coronary imaging. However, further validations are needed to overcome several scientific and computational challenges before these methods are applied in everyday clinical practice.
Effectiveness of Manual Hysteroscopic Tissue Removal Device for Intrauterine Polyps in Infertile Women in Both Operating and Office Settings
Authors: Wang Chen , Chen Hui , Morgan India , Prytkova Valeriya , Kohl-Thomas Belinda , Parry J. Preston , Lindheim Steven R.
Published: April 2024

Background: Mechanical hysteroscopic tissue removal (mHTR) systems are widely used for removing intrauterine pathology. Given the startup and procedural costs for electrically powered mechanical units, disposable manual mHTR systems have been developed. Methods: With little published, we describe its effectiveness for hysteroscopic intrauterine polypectomy. Results: One-hundred fifty-seven infertile women underwent hysteroscopic polypectomy with the manual mHTR device. Complete removal was accomplished in all but three cases, with blood loss being <10 mL and all specimens deemed sufficient for histopathologic diagnosis. Conclusions: These results suggest that the disposable manual mHTR system is effective in removing endometrial polyps. Head-to-head comparisons with other alternative technologies are needed.
Successful Treatment with Bimekizumab of a Psoriatic Patient Undergoing Hemodialysis: A Case Report and Review of the Literature
Authors: Bernardini Nicoletta , Ambrosio Luca , Tolino Ersilia , Proietti Ilaria , Skroza Nevena , Potenza Concetta
Published: April 2024

Background/Objectives: Treating psoriasis patients requires the consideration of potential underlying complications like latent viral infections and chronic kidney disease, which may influence therapy selection. Case presentation: A patient with end-stage kidney disease (ESKD) undergoing hemodialysis (HD) was successfully treated with bimekizumab, an IgG1 humanized monoclonal antibody inhibiting interleukin (IL)-17A and IL-17F. This case appears to be the first documented instance of effective anti-IL-17A/IL-17F antibody treatment in a psoriasis patient undergoing HD, with a sustained positive response for eight months. Discussion: Studies indicate the comparable pharmacokinetics, efficacy, and safety of certain psoriasis drugs in patients with chronic kidney disease (CKD) and those with normal renal function. The positive clinical outcome observed following treatment with bimekizumab aligns with the existing literature on this topic. However, further studies are needed to objectively evaluate the pharmacokinetics, efficacy, and safety of this drug in this specific setting. Conclusions: This documented case represents the first known use of bimekizumab to treat psoriasis in patients undergoing dialysis, suggesting its potential effectiveness and safety in this population.
Rapid Estimation Model for Wake Disturbances in Offshore Floating Wind Turbines
Authors: Zhao Liye , Gong Yongxiang , Li Zhiqian , Wang Jundong , Xue Lei , Xue Yu
Published: April 2024

The precise wake model is crucial for accurately estimating wind farm loads and power, playing a key role in wake control within wind farms. This study proposes a segmented dual-Gaussian wake model, which is built upon existing dual-Gaussian wake models but places greater emphasis on the influence of initial wake generation and evolution processes on the wind speed profile in the near-wake region. The enhanced model optimizes the wake speed profile in the near-wake region and improves the accuracy of wake diffusion throughout the entire flow field. Furthermore, the optimized dual-Gaussian wake model is utilized to estimate the power output and blade root vibration loads in offshore wind farms. Through comparative analysis of high-fidelity simulation results and actual measurement data, the accuracy of the optimized dual-Gaussian wake model is validated. This approach offers high computational efficiency and provides valuable insights for load fluctuations and power estimation, thereby advancing the development of wake control strategies rapidly.
Evaluation of Soil Quality and Analysis of Barriers of Protection Forests along Tarim Desert Highway Based on a Minimum Data Set
Authors: Liu Wenhe , Li Lin , He Xuemin , Lv Guanghui
Published: April 2024

To gain a thorough grasp of the soil quality conditions in the preservation forests along the Tarim Desert Highway, a detailed assessment of the research area’s soil quality is necessary, along with the identification of any potential obstacles. This evaluation should identify any potential obstacles and provide a theoretical basis for the sustainable utilization and precise management of protection forest soils. This paper examines the protection forest along the Tarim Desert Highway as the study area. To characterize the features of the soil quality, thirteen indicators of the chemical, physical, and biological composition of the soil were examined. The principal component analysis method was used to construct the minimum dataset (MDS) for soil quality evaluation. The diagnostic model for obstacle factors was combined with the MDS to explore the soil quality characteristics and obstacle factors in the study region. The findings indicated that (1) the constructed indexes of the MDS of protection forest soil in the study area included soil ammonium nitrogen (NH4+-N); quick-acting phosphorus (AvP); organic carbon (SOC); alkaline phosphatase (AP); and total salt (SS); (2) soil quality based on the MDS and the total dataset (TDS) showed a significant positive correlation (R2 = 0.748; p < 0.05), and the research region’s soil quality were all in the medium and below level (100% of SQI ≤ 0.6), showing the status quo of high soil quality in the two ends of the shelterbelt forest and the tower center area, while the other areas were relatively low; (3) according to the findings of the soil barrier analysis, the two main obstacles influencing the soil quality of the shelterbelt forest at this time are NH4+-N and SOC, and that the soil quality of the shelterbelt forest could be improved by artificially increasing the inputs of nutrients and precise conservation measures, promoting the overall function of artificial protective forests on desert highways. In addition to providing a solid scientific foundation for the sustainable use and maintenance of shelterbelt forests along the Tarim Desert Highway, this study is also an invaluable resource for researching the soil quality of artificial shelterbelt forests in arid regions.
The Landscape of Tranquility in Sweden: Lessons for Urban Design from Crowdsourced Data and Deep Learning
Authors: Zeng Yijun , Deal Brian , Ask Susan , Huang Tianchen
Published: April 2024

Tranquility is typically associated with low noise levels and remote natural areas. Various methods for preserving potentially tranquil places have been proposed, although these typically involve setting aside places with low noise levels located in remote areas. To gain the benefits of tranquility in accessible urban areas, we need to identify the characteristics of tranquil spaces. This study focuses on the landscape-based, visual aspects of the phenomena. We investigated the role of visual context using a nationwide dataset of crowdsourced photographs from Sweden. Text mining identified personal perception and accompanying photographs identified the physical features. The photographs were characterized by time period and landscape conditions using computer vision technology. We found that waterbodies consistently enhanced tranquil views, while grass, flowers, and other dense vegetation were generally not well connected. Trees were positively correlated during daylight hours but had a negative impact at night. Dynamic objects such as people and vehicles were negatively associated, potentially due to aural considerations. Their effect was less significant during hours when noise would generally be less of a factor. This study provides insights for future research and design practices aimed at promoting tranquil experiences in urban environments and demonstrates the potential for crowdsourced data to help understand the qualities of built environments as perceived by the public.
Spatial-Temporal Assessment of Urban Resilience to Disasters: A Case Study in Chengdu, China
Authors: Wei Yang , Kidokoro Tetsuo , Seta Fumihiko , Shu Bo
Published: April 2024

Urban areas with an imbalanced vulnerability to disasters have garnered attention. Building an urban resilience index helps to develop a progressively favored instrument for tracking progress toward disaster-resilient cities. However, there remains a lack of empirical studies on measuring urban resilience, with limited focus on the spatial-temporal characteristics of urban resilience to disasters, particularly relevant in developing nations like China. Thus, a refined urban resilience index to disasters based on the subcomponents of infrastructure, environment, socio-economy, and institution is suggested in this study. This index-based assessment framework is applied and validated to measure the spatial-temporal resilience using a real-world case study in Chengdu, China. The main findings of this study indicate that: (1) the overall urban resilience of Chengdu has been growing toward better conditions, with infrastructural resilience accounting for the majority of this growth. (2) The distribution of urban resilience exhibits a regional disparity and a spatially polarized pattern. (3) The agglomeration characteristics of urban resilience are significant. (4) There is a clear regional mismatch in the distribution of urban resilience to disaster risk. The validated model offers a comprehensive and replicable approach for urban resilience assessment and planning, especially for disaster-frequent regions.
A Surface Hydrothermal Source of Nitriles and Isonitriles
Authors: Rimmer Paul B. , Shorttle Oliver
Published: April 2024

Giant impacts can generate transient hydrogen-rich atmospheres, reducing atmospheric carbon. The reduced carbon will form hazes that rain out onto the surface and can become incorporated into the crust. Once heated, a large fraction of the carbon is converted into graphite. The result is that local regions of the Hadean crust were plausibly saturated with graphite. We explore the consequences of such a crust for a prebiotic surface hydrothermal vent scenario. We model a surface vent fed by nitrogen-rich volcanic gas from high-temperature magmas passing through graphite-saturated crust. We consider this occurring at pressures of 1–1000bar and temperatures of 1500–1700 ∘C. The equilibrium with graphite purifies the leftover gas, resulting in substantial quantities of nitriles (0.1% HCN and 1ppm HC3N) and isonitriles (0.01% HNC) relevant for prebiotic chemistry. We use these results to predict gas-phase concentrations of methyl isocyanide of ∼1 ppm. Methyl isocyanide can participate in the non-enzymatic activation and ligation of the monomeric building blocks of life, and surface or shallow hydrothermal environments provide its only known equilibrium geochemical source.
Characterisation of Adobe and Mud–Straw for the Restoration and Rehabilitation of Persian Historical Adobe Buildings
Authors: Hejazi Bina , Luz Corinna , Grüner Friedrich , Frick Jürgen , Garrecht Harald
Published: April 2024

In the restoration or rehabilitation of traditional buildings, compatible materials with known characteristics must be used. However, the existing literature lacks comprehensive studies on the characterisation of Persian mud–straw plaster, focusing primarily on Persian adobe. Moreover, previous research on Persian adobe has primarily employed XRF and XRD tests, neglecting ion chromatography, moisture sorption isotherm determination, and thermogravimetric analysis with differential scanning calorimetry. Consequently, there is a shortage of information regarding the elemental composition, mineralogical characteristics, moisture sorption behaviour, and thermal properties of Persian mud–straw plaster, as well as Persian adobe bricks. This paper aims to address this research gap by examining historical and new adobe bricks and mud–straw plaster used in Iran, utilising a comprehensive array of analytical techniques. The results from XRF analysis reveal relatively similar chemical compositions across all samples, while XRD analysis indicates predominantly similar mineral phases. Ion chromatography results demonstrate higher conductivity and chloride concentrations in the mud–straw samples than the adobe samples, with higher values for new samples than historical ones. Freshly used straw, clay, or soil may have higher chloride concentrations caused by the arid climate and soil salinisation in the area. Additionally, moisture sorption isotherm determination results show that adobe and mud–straw plaster with a higher salt load of chlorides have significantly higher moisture absorption. The increased straw quantity in the samples increases the moisture content. Furthermore, thermogravimetric analysis and differential scanning calorimetry indicate that, at low heating, adobe and mud–straw plaster lose water due to dehydration, and at high heating, they lose carbon dioxide due to decarboxylation. The comprehensive characterisation of Persian adobe and mud–straw plaster in this study fills a significant gap in the literature and offers invaluable insights for informing restoration and rehabilitation processes, ensuring the compatibility of the materials used.
New Method for Determining Mode-I Static Fracture Toughness of Coal Using Particles
Authors: Cheng Qiang , Huang Gun , Zheng Jie , Liang Qinming
Published: April 2024

Understanding the mechanical properties of coal is crucial for efficient mining and disaster prevention in coal mines. Coal contains numerous cracks and fissures, resulting in low strength and challenges in preparing standard samples for testing coal fracture toughness. In engineering, indicators such as the hardness coefficient (f value) and Hardgrove grindability index (HGI) are straightforward to measure. Various experiments, including drop weight, grinding, uniaxial compressive strength and three-point bending experiments, were conducted using notched semi-circular bend (NSCB) specimens and particle sizes of 1–2 mm/0.425–1 mm. Theoretical and experimental results indicate that the hardness coefficient of coal and rock is proportional to the crushing work ratio and inversely proportional to the mean equivalent diameter. Moreover, the square of the fracture toughness of coal and rock is directly proportional to the crushing work ratio, inversely proportional to the newly added area, directly proportional to the mean equivalent diameter and directly proportional to the hardness coefficient. The Mode-I fracture toughness of coal and rock can be rapidly determined through the density, the equivalent diameter after crushing and the elastic modulus, with experimental verification of its accuracy. Considering that smaller particle sizes exhibit greater resistance to breakage, the distribution mode of new surface areas after particle breakage was established, influenced by the initial particle size and the energy of a single broken particle. This study can assist in quickly and accurately determining the fracture toughness of coal.
Polyhydroxyalkanoate Production from Eucalyptus Bark’s Enzymatic Hydrolysate
Authors: Rodrigues Thomas , Torres Cristiana A. V. , Marques Susana , Gírio Francisco , Freitas Filomena , Reis Maria A. M.
Published: April 2024

In recent years, polyhydroxyalkanoates (PHAs) have gained notoriety because of their desirable properties that include proven biodegradability, biocompatibility, and thermal stability, which make them suitable alternatives to fossil-based polymers. However, the widespread use of PHAs is still challenging because of their production costs, which are greatly associated with the cultivation medium used for bacterial cultivation. In Portugal, one-quarter of the forest area is covered by Eucalyptus globulus wood, making its residues a cheap, abundant, and sustainable potential carbon source for biotechnological uses. In this work, eucalyptus bark was used as the sole feedstock for PHA production in a circular bioeconomic approach. Eucalyptus bark hydrolysate was obtained after enzymatic saccharification using Cellic® CTec3, resulting in a sugar-rich solution containing glucose and xylose. Although with differing performances, several bacteria were able to grow and produce PHA with distinct compositions, using the enzymatic hydrolysate as the sole carbon source. Pseudomonas citronellolis NRRL B-2504 achieved a high cellular growth rate in bioreactor assays (24.4 ± 0.15 g/L) but presented a low accumulation of a medium-chain-length PHA (mcl-PHA) comprising the monomers hydroxydecanoate (HD, 65%), hydroxydodecanoate (HDd, 25%), and hydroxytetradecanoate (HTd, 14%). Burkholderia thailandensis E264, on the other hand, reached a lower cellular growth rate (8.87 ± 0.34 g/L) but showed a higher biopolymer accumulation, with a polyhydroxybutyrate (PHB) content in the cells of 12.3 wt.%. The new isolate, Pseudomonas sp., revealed that under nitrogen availability, it was able to reach a higher accumulation of the homopolymer PHB (31 wt.%). These results, although preliminary, demonstrate the suitability of eucalyptus bark’s enzymatic hydrolysate as a feedstock for PHA production, thus offering an exciting avenue for achieving sustainable and environmentally responsible plastic products from an undervalued forestry waste.
Investigation of Microstructure, Oxides, Cracks, and Mechanical Properties of Ti-4Al-2V Joints Prepared Using Underwater Wet Laser Welding
Authors: Zhu Yonghui , Zhang Yujia , Li Congwei , Zhu Jialei , Wang Lu , Fu Chao
Published: April 2024

Developing advanced underwater welding technology for titanium, which is the key structural material for underwater applications, is of great significance for the design, fabrication, and maintenance of submarine equipment. In this study, in order to investigate the underwater welding microstructure and mechanical properties of Ti-4Al-2V alloy, underwater wet laser welding was conducted on Ti-4Al-2V alloy using varying laser power. The microstructure and properties of the welding joints were characterized and analyzed. The microstructure of the heat-affected zone and fusion zone in the welding joints are not significantly different from those of welding in air, but a mixed oxide layer composed of Al2O3 and TiO2 is formed on the surface of the fusion zone. Due to internal stress, a large number of cracks initiate on the oxide layer and propagate to the joints. In the 4 kW and 5 kW joints, a penetrating crack formed due to the excessive accumulation of internal stress breaking up the α phase. The mechanical properties of the joints are significantly affected by the laser power. The tensile strength of the 3 kW and 4 kW joints is comparable to that of the base metal, which is about 600 MPa, while the 5 kW joint shows brittle fracture with no plastic deformation and 228 MPa strength. This research lays a solid foundation for understanding the underwater wet laser welding behavior of titanium alloys.
Exploring the Potential Application of an Innovative Post-Weld Finishing Method in Butt-Welded Joints of Stainless Steels and Aluminum Alloys
Authors: Łastowska Olga , Starosta Robert , Jabłońska Monika , Kubit Andrzej
Published: April 2024

The prerequisite of the weld bead finishing is intricately linked to the quality of the welded joint. It constitutes the final, yet pivotal, stage in its formation, significantly influencing the reliability of structural components and machines. This article delineates an innovative post-weld surface finishing method, distinguished by the movement of a specialized cutting tool along a butt weld. This method stands out due to its singular approach to machining allowance, wherein the weld bead height is considered and eradicated in a single pass of the cutting tool. Test samples were made of AISI 304L, AISI 316L stainless steels and EN AW-5058 H321, EN AW-7075 T651 aluminum alloys butt-welded with TIG methods. Following the welding process, the weld bead was finished in accordance with the innovative method to flush the bead and the base metal’s surface. For the quality control of welded joints before and after the weld finishing, two non-destructive testing methods were chosen: Penetrant Testing (PT) and Radiographic Testing (RT). This article provides results from the examination of 2D profile parameters and 3D stereometric characteristics of surface roughness using the optical method. Additionally, metallographic results are presented to assess changes in the microstructure, the microhardness, and the degree of hardening within the surface layer induced by the application of the innovative post-weld finishing method.
The Use of Sargassum spp. Ashes Like a Raw Material for Mortar Production: Composite Performance and Environmental Outlook
Authors: Lyra Gabriela Pitolli , Colombo Ana Letícia , Duran Afonso José Felício Peres , Parente Igor Machado da Silva , Bueno Cristiane , Rossignolo João Adriano
Published: April 2024

The accumulation of brown algae from the genus Sargassum has been increasing over the years in coastal regions of the Caribbean, Africa, Brazil, and Mexico. This causes harmful effects to the ecosystem, human health, the economy, and the climate due to gas emissions from its decomposition process. There is the possibility of this biomass being reused in civil construction, and some studies have been carried out on its application to common Portland cement mortar. As such, the objective of this study is to evaluate the potential of sargassum ash as a mineral addition to partially replace fine aggregates in Portland cement mortar. Characterization of the raw materials was carried out through X-ray fluorescence spectroscopy, loss on ignition, particle size distribution, Brunauer–Emmett–Teller (BET) analysis, real density, X-ray diffraction, scanning electron microscopy, and dispersion spectroscopy of electrons. The mortars were prepared by partially replacing the fine aggregate (sand) with sargassum ash at 0%, 5%, 10%, and 20%. Mortar performance was evaluated through water absorption, apparent porosity, apparent specific mass, and compressive strength 7, 28, and 63 days after curing. Lastly, a life cycle assessment was conducted in accordance with ISO standards 14040:2006 and 14044:2006. The results showed that replacing sand with sargassum ash increases water absorption and apparent porosity, and decreases the apparent specific mass and compressive strength as replacement increases. Nevertheless, the compressive strength results after 63 days for 5 and 10% replacement did not differ statistically from reference values. The life cycle assessment indicated that mortars with partial replacement of sand by sargassum ash show positive environmental impacts when compared to reference values for most categories, regardless of the scenario analyzed, especially for mortar with 10% replacement. As such, the use of sargassum ash at 10% does not alter the mortar’s compressive strength values after 63 days, but does reduce its environmental impact. The application of this biomass in civil construction materials provides a destination for this algae, and that can be a solution to mitigate the social, environmental, and economic problems it has been causing.
Fixed Point Results in Modified Intuitionistic Fuzzy Soft Metric Spaces with Application
Authors: Gupta Vishal , Gondhi Aanchal , Shukla Rahul
Published: April 2024

This paper establishes a new type of space, modified intuitionistic fuzzy soft metric space (MIFSMS). Basic properties and topological structures are defined in the setting of this new notion with valid examples. Moreover, we have given some new results along with suitable examples to show their validity. An application for finding the solution of an integral equation is also given by utilizing our newly developed results.
A Bidirectional Arabic Sign Language Framework Using Deep Learning and Fuzzy Matching Score
Authors: Mosleh Mogeeb A. A. , Assiri Adel , Gumaei Abdu H. , Alkhamees Bader Fahad , Al-Qahtani Manal
Published: April 2024

Sign language is widely used to facilitate the communication process between deaf people and their surrounding environment. Sign language, like most other languages, is considered a complex language which cannot be mastered easily. Thus, technology can be used as an assistive tool to solve the difficulties and challenges that deaf people face during interactions with society. In this study, an automatic bidirectional translation framework for Arabic Sign Language (ArSL) is designed to assist both deaf and ordinary people to communicate and express themselves easily. Two main modules were intended to translate Arabic sign images into text by utilizing different transfer learning models and to translate the input text into Arabic sign images. A prototype was implemented based on the proposed framework by using several pre-trained convolutional neural network (CNN)-based deep learning models, including the DenseNet121, ResNet152, MobileNetV2, Xception, InceptionV3, NASNetLarge, VGG19, and VGG16 models. A fuzzy string matching score method, as a novel concept, was employed to translate the input text from ordinary people into appropriate sign language images. The dataset was constructed with specific criteria to obtain 7030 images for 14 classes captured from both deaf and ordinary people locally. The prototype was developed to conduct the experiments on the collected ArSL dataset using the utilized CNN deep learning models. The experimental results were evaluated using standard measurement metrics such as accuracy, precision, recall, and F1-score. The performance and efficiency of the ArSL prototype were assessed using a test set of an 80:20 splitting procedure, obtaining accuracy results from the highest to the lowest rates with average classification time in seconds for each utilized model, including (VGG16, 98.65%, 72.5), (MobileNetV2, 98.51%, 100.19), (VGG19, 98.22%, 77.16), (DenseNet121, 98.15%, 80.44), (Xception, 96.44%, 72.54), (NASNetLarge, 96.23%, 84.96), (InceptionV3, 94.31%, 76.98), and (ResNet152, 47.23%, 98.51). The fuzzy matching score is mathematically validated by computing the distance between the input and associative dictionary words. The study results showed the prototype’s ability to successfully translate Arabic sign images into Arabic text and vice versa, with the highest accuracy. This study proves the ability to develop a robust and efficient real-time bidirectional ArSL translation system using deep learning models and the fuzzy string matching score method.
Analyzing Primary Sector Selection for Economic Activity in Romania: An Interval-Valued Fuzzy Multi-Criteria Approach
Authors: Ionașcu Alina Elena , Goswami Shankha Shubhra , Dănilă Alexandra , Horga Maria-Gabriela , Barbu Corina Aurora , Şerban-Comǎnescu Adrian
Published: April 2024

This study presents an in-depth analysis of the selection process for primary sectors impacting the economic activity in Romania, employing an interval-valued fuzzy (IVF) approach combined with multi-criteria decision-making (MCDM) methodologies. This research aims to identify eight key criteria influencing the selection of Romanian primary sectors, including technology adaptation, infrastructure development and investment, gross domestic product (GDP), sustainability, employment generation, market demand, risk management and government policies. The current analysis evaluates eight primary sector performances against these eight criteria through the application of three MCDM methods, namely, Simple Additive Weighting (SAW), Weighted Product Model (WPM), and Weighted Aggregated Sum Product Assessment (WASPAS). Ten economic experts comprising a committee have been invited to provide their views on the criteria’s importance and the alternatives’ performance. Based on the decision-maker’s qualitative judgement, GDP acquires the highest weightage, followed by environmental impact and sustainability, thus indicating the most critical factors among the group. The IVF-MCDM hybrid model indicates the energy sector as Romanian primary sector with the most potential, followed by the agriculture and forestry sector among the list of eight alternatives. It also explores the robustness of results by considering sensitivity analysis and the potential impacts of political and international factors, such as pandemics or armed conflicts, on sector selection. The findings indicate consistency in sector rankings across the different methodologies employed, underscoring the importance of methodological choice and criteria weighting. Additionally, this study sheds light on the potential influence of political and international dynamics on sector prioritization, emphasizing the need for comprehensive decision-making frameworks in economic planning processes.
Multilevel Fuzzy Inference System for Estimating Risk of Type 2 Diabetes
Authors: Tašić Jelena , Nagy-Perjési Zsófia , Takács Márta
Published: April 2024

In this paper, we present a multilevel fuzzy inference model for predicting the risk of type 2 diabetes. We have designed a system for predicting this risk by taking into account various factors such as physical, behavioral, and environmental parameters related to the investigated patient and thus facilitate experts to diagnose the risk of diabetes. The important risk parameters of type 2 diabetes are identified based on the literature and the recommendations of experts. The parameters are scaled and fuzzified on their own universe and, based on the experts’ recommendation, fuzzy inference subsystems are created with 3–4 related risk parameters to calculate the risk level. These sub-systems are then arranged into Mamdani-type inference systems so that the system calculates an aggregated risk level. The overview of the large number of diverse types of risk factors, which may be difficult for specialists and doctors, is facilitated by the proposed system.
Effect of Hot Deformation and Heat Treatment on the Microstructure and Properties of Spray-Formed Al-Zn-Mg-Cu Alloys
Authors: Cao Lingfei , Lin Xiaomin , Zhang Zhenghao , Bai Min , Wu Xiaodong
Published: April 2024

Spray forming is a manufacturing process that enables the production of high-performance metallic materials with exceptional properties. Due to its rapid solidification nature, spray forming can produce materials that exhibit fine, uniform, and equiaxed microstructures, with low micro-segregation, high solubility, and excellent workability. Al-Zn-Mg-Cu alloys have been widely used in the aerospace field due to their excellent properties, i.e., high strength, low density, and outstanding machinability. The alloy manufactured by spray forming has a combination of better impact properties and higher specific strength, due to its higher cooling rate, higher solute concentration, and lower segregation. In this manuscript, the recent development of spray-formed Al-Zn-Mg-Cu alloys is briefly reviewed. The influence of hot working, i.e., hot extrusion, hot forging, and hot rolling, as well as different heat treatments on the property and microstructure of spray-formed Al-Zn-Mg-Cu alloys is introduced. The second phases and their influence on the microstructure and mechanical properties are summarized. Finally, the potential in high-temperature applications and future prospects of spray-formed aluminum alloys are discussed.
Investigating the Thermal Conductance of the Cu/Si Interface Using the Molecular Dynamics Method
Authors: Liu Shuai , Zhi Yueyi , Song Hongquan , Li Huijin , Wang Weiping , Hu Xiaoyan , Zhang Dongbo
Published: April 2024

Investigating thermal transport at the Cu/Si interface holds significant importance, as understanding interface thermal conductance is crucial for enhancing materials interface thermal management, designing thermal interface materials, and improving the performance of thermoelectric devices. In this study, we conducted molecular dynamics simulations in conjunction with the Green–Kubo relation to calculate the thermal conductance of the Cu/Si interface. We successfully obtained Cu/Si interface potentials using the lattice inversion method. Our findings revealed that the thermal conductance of the Cu/Si interface is notably influenced by the interface structure. Specifically, the thermal conductance of the Cu(001)/Si(001) interface and the Cu(111)/Si(111) interface are similar, and both are higher than that of the Cu(110)/Si(110) interface. Furthermore, through first-principles calculations of the adhesion energy, we discovered that interface binding strength plays a critical role in determining interface thermal transport properties, and the influence of pressure was also discussed. This study contributes not only to the understanding of the thermal transport mechanisms at the Cu/Si interface but also provides important insights for designing novel interface materials.
Simulation Models in a Fluidity Test of the Al-Si Alloy
Authors: Šolc Marek , Blaško Peter , Petrík Jozef , Girmanová Lenka , Blašková Andrea , Małysa Tomasz , Furman Joanna , Socha Vladimír
Published: April 2024

The goal of the fluidity test is to evaluate the ability of the melt to fill the cavity of the mold, which is one of the factors affecting the final quality of the castings. It is a technological test that is basically not standardized, therefore it is realized in different forms, for example using “horizontal” and “vertical” molds. The “horizontal” mold makes it easier to fulfill the condition of repeatability, therefore it was used to calculate the capability of the test by the Measurement Systems Analysis (MSA) method. The results of the tests in both molds were used to calculate regression equations that allow the fluidity to be determined with strong reliability based on variables such as melt temperature, casting speed, and mold temperature. In addition, the effects of input data variability (uncertainty) on the resulting fluidity value were analyzed using regression equations and the Monte Carlo simulation. The contribution of the article is the analysis of the capability of the measurement process of the fluidity and a prediction of the results of its tests using the Monte Carlo simulation method.
Numerical Simulation of Cathode Nodule Local Effects
Authors: Wang Xiaoyu , Li Chun , Tie Jun
Published: April 2024

As one of the main factors decreasing current efficiency and product quality, the growth of nodules deserves attention in the copper electrorefining process. Three-dimensional (3D) Finite Element Method models combining tertiary current distribution and fluid flow were established in this study to investigate the details of the growth of columnar nodules, including the electrolyte flow around the nodule and its effects. Compared with an inert nodule, a significant impact of the electrochemical reaction of an active nodule has been observed on the fluid flow, which may be one of the reasons for the formation of small nodule clusters on the cathode. Furthermore, the local current density is not even on the nodule surface under the comprehensive influence of local electrolyte flow, local overvoltage, and the angle with the anode surface. Thus, the head of an active nodule grows faster than the root, and the upper parts grow faster than the lower parts, leading to asymmetric growth of the nodules.