bluuebunny/crossref_metadata_2025 huggingface dataset:
छत्तीसगढ़ की कृषि अर्थव्यवस्था का अध्ययन 21वीं शताब्दी के परिप्रेक्ष्य में
Authors: कु. कुसुम देवांगान  , डॉ. जी. आर. साहू
Published: October 2024

कृषि मानव जगत की बड़ी पुरानी परंपरा है, इसकी प्राचीनता उतनी ही है, जितनी मानव सभ्यता प्राचीन काल से ही कृषि आय का प्रमुख स्त्रोत रहा है। मानव जीवन का विकास कृषि पर आधारित रहा है। प्राचीन काल के राजा से आधुनिक काल के ब्रिटिश गवर्नर ने भी उन्हीं क्षेत्र को सर्वप्रथम अपने अधीन किया जो कृषि की दृष्टि से उन्नत थी। छत्तीसगढ़ की अर्थव्यवस्था कृषि प्रधान अर्थव्यवस्था रही है। प्राचीन काल से यहां के लोगों के आर्थिक आजीविका का साधन कृषि रहा है। अंचल में क्रियाशील जनसंख्या के 80% लोगों की आजीविका कृषि से ही चलती है। छत्तीसगढ़ के लगभग 88.37% क्षेत्रों में खाद्यानों का उत्पादन होता है, जिनमें चावल, गेहंू, मक्का, गन्ना, सोयाबीन, दालें, ज्वार, बाजरा, कोदो आदि है। छत्तीसगढ़ के किसान भाई जहां पहले अपने खेत से अपना पेट भी मुश्किल से भर पाते थे, वहां आज वह दूसरों को अपनी पैदावार बेच लाभ कमा रहे हैं और गरीबी के दलदल से निकाल कर खुशहाली की ओर बढ़ रहे हैं।
कृषि की अवधारणा या संकल्पना की व्याख्या बड़ी कठिन है क्योंकि यह एक अत्यंत व्यापक शब्द है ”ऐगर“ (Ager) शब्द का अर्थ खेत या मिट्टी है और ”कल्चर“ (Culture) शब्द का अर्थ देखरेख से है, परन्तु कृषि में केवल इतनी ही बातें सम्मिलित नहीं है। इसके अंतर्गत खेत की जुताई और फसल की बुवाई के अतिरिक्त फलोत्पादन, वृक्षारोपण आदि सम्मिलित है। भोजन की प्राप्ति इसका मुख्य ध्येय है। इसके साथ ही साथ कच्चे माल का उत्पादन करना भी इसका मुख्य लक्ष्य है।
EMPLOYEE PERSPECTIVES ON AI UTILIZATION IN THE MANUFACTURING SECTOR WITH SPECIAL REFERENCE TO CHHATRAL GIDC IN GUJARAT STATE: A SURVEY-BASED STUDY
Authors: Dr. Mayur B. Patel  , Dr. Dhaval M. Patel
Published: October 2024

Artificial intelligence (AI) has revolutionised the industrial industry by bringing with it the promise of greater productivity, accuracy, and competitiveness. The purpose of this survey-based study is to investigate how employees feel about the use of AI in manufacturing enterprises in Gujarat State, India's Chhatral GIDC (Gujarat Industrial Development Corporation). The purpose of the study is to learn more about the attitudes, beliefs, and difficulties that employees have when integrating AI technologies. Structured questionnaires were used to gather data from a representative sample of employees in Chhatral GIDC's manufacturing sectors. The results shed important light on the variables affecting the adoption of AI, emphasising how organisational environment and local dynamics affect employee reactions.
Mulheres que Inspiram: Impacto de uma websérie para divulgação de mulheres que contribuíram com a história da humanidade
Authors: SOARES Marisele dos Santos , ROSA Ana Carolina de Souza da , CARPES Pâmela Billig Mello
Published: October 2024

A divulgação da participação de mulheres em diferentes áreas da sociedade é importante, pois ainda há barreiras que limitam a representatividade feminina em vários espaços. O uso das redes sociais, em especial o Instagram, tem potencial para a popularização de conhecimentos, devido ao seu amplo alcance. Nosso objetivo foi produzir e avaliar o impacto de uma WebSérie na divulgação e popularização de personalidades femininas que contribuíram para a história da humanidade. A WebSérie foi produzida utilizando as plataformas Canva (canva.com) e Clipchamp (app.clipchamp.com) e publicada na rede social Instagram do Grupo de Pesquisa em Fisiologia da Universidade Federal do Pampa. Os resultados demonstram que a WebSérie apresentou um amplo alcance, possibilitou uma ampliação de conhecimentos histórico, social e cultural aos seguidores, além de ter o potencial de inspirar meninas e mulheres a buscarem diferentes oportunidades profissionais e seu empoderamento diante da sociedade.
Educação em saúde no contexto do Sistema Prisional de Viçosa-MG: relato de experiência
Authors: FREITAS Ricardo Eustaquio de , NATIVIDADE Deisiane Moreira , DIAS Maria Fernanda Barbosa
Published: October 2024

A Associação de Assistência aos Condenados (APAC) é uma entidade jurídica presente em diversas regiões do Brasil e que tem como objetivo promover a humanização das prisões e, por conseguinte, evitar a reincidência do recuperando no crime. Nessa parceria, os estudantes vinculados à Frente de População Privada de Liberdade (FPPL) da LUMA executam atividades de educação em saúde com os recuperandos que estão em cumprimento de pena no regime fechado na APAC. O principal objetivo do presente relato de experiência é expor as observações e impressões dos integrantes da LUMA da Universidade Federal de Viçosa (UFV) em atividade educativa sobre Infecções Sexualmente Transmissíveis (IST) na APAC de Viçosa-MG. Integrantes da da liga, junto à comunidade privada de liberdade, fizeram uma atividade em formato de grupo de conversa, a qual iniciou-se com uma dinâmica de jogo de tabuleiro, e ao final uma apresentação de slides interativa. Na avaliação entre os membros da LUMA, em reunião posterior ao encontro, foi possível identificar a necessidade de se repetir atividades como essa, mas também em outros temas como saúde reprodutiva e saúde mental.
The Performance Implications of Management Control Systems and Dynamic Capabilities: Evidence from Vietnam
Authors: Huyen Mong Le  , Trang Cam Hoang
Published: October 2024

Drawing on the resource-based view and dynamic-capability view, this study examines the relationship between the interactive use of management control systems, dynamic capabilities, and firm performance in the Vietnamese information and communication technology industry. The research model and hypotheses have been tested by partial least squares-structural equation modelling (PLS-SEM) with 240 survey samples obtained from managers working in Vietnamese information and communication technology firms. The results indicate that the interactive use of management control systems has a positive effect on dynamic capabilities. Additionally, both the interactive use of management control systems and dynamic capabilities have direct positive effects on firm performance. The results reveal that dynamic capabilities complementary mediate the relationships between the interactive use of management control systems and firm performance. This study provides theoretical and managerial implications for Vietnamese information and communication technology firms that are striving to develop management control systems and dynamic capabilities for enhancing firm performance.
THE IMPACT OF AUGMENTED REALITY (AR) ON CUSTOMER EXPERIENCE MANAGEMENT
Authors:   Assistant Professor, St. Marys College, Hyderabad., Raval Himani , Aiman Ailza ,   Student, St. Marys College, Hyderabad.
Published: October 2024

This study explores the impact of Augmented Reality (AR) technology on customer engagement, the influence of cultural factors on AR adoption, and the long-term effects of AR on customer loyalty and brand advocacy. Through a comprehensive analysis of survey data, three key hypotheses were tested. First, the effectiveness of AR on customer engagement was evaluated, revealing that AR significantly enhances customer interaction and engagement with brands across diverse industries. Second, the study investigated the role of cultural factors in moderating AR adoption. The findings indicate that cultural influences significantly shape customer perception and comfort levels with AR, especially when experiences are tailored to specific cultural contexts. Lastly, the long-term impact of AR on customer loyalty was assessed, showing that AR experiences positively influence brand loyalty and the likelihood of customers recommending brands to others. The results from this research support the integration of AR technology as a strategic tool for enhancing customer engagement and loyalty, particularly when cultural considerations are incorporated into AR experiences. The implications of these findings suggest that businesses adopting AR can benefit from increased customer satisfaction, deeper engagement, and stronger brand advocacy, positioning AR as a critical component in future marketing and customer experience strategies.
EFFECT OF COOKING TIME ON BIOCHEMICAL PROPERTIES OF RAFFIA (RAFFIA HOOKERI) HEART CONSUMED AS VEGETABLE IN COTE DIVOIRE
Authors:   Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Biological Resources Valorization. University Felix Houphouet-Boigny, Abidjan, Cote dIvoire., Cisse M. , Koffi D.M ,   Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Biological Resources Valorization. University Felix Houphouet-Boigny, Abidjan, Cote dIvoire., Doue G.G ,   Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Biological Resources Valorization. University Felix Houphouet-Boigny, Abidjan, Cote dIvoire., Saki S.J ,   Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Biological Resources Valorization. University Felix Houphouet-Boigny, Abidjan, Cote dIvoire.
Published: October 2024

Raffia (Raphia hookeri Mann & Wendl.) heart, a little-known vegetable, is usually eaten after cooking in some regions of the Cote dIvoire. The proximate composition of the fresh state and the effect of cooking time (15, 30 and 45 min) on biochemical parameters were investigated. The results show that fresh raffia heart contains nutrients such as proteins (14.53 Â± 0.03 g/100g), lipids (2.60 Â± 0.10 g/100g), total sugars (35.61 Â± 0.13 g/100g) and phytochemicals, in particular total polyphenols (5.86 Â± 0.38 g/100g), flavonoids (0.75 Â± 0.20 g/100g) and tannins (1.93 Â± 0.9 g/100g). It is also rich in fibre (23.30 Â± 0.75 g/100g) and ash (12.60 Â± 0.02 g/100g), which contain minerals. Cooking for 15 minutes did not affect the protein content (14.53 Â± 0.04 g/100g), but the content of total polyphenols (8.23 Â± 0.39 g/100g), lipids (3.60 g/100g) and energy (295.84 Â± 3.96 kcal/100g) increased by 28.79%, 2.77% and 0.74% respectively. Conversely, fibre (22.80 Â± 0.67 g/100g), flavonoids (0.54 Â± 0.10 g/100g) and tannins (1.19 Â± 0.13 g/100g) decreased by 2.14%, 28% and 38.34% respectively. Except for lipids, the values of other nutrients decreased after 30 and 45 minutes of cooking. The nutrient values of raffia hearts cooked for 15 minutes are high, which could help to meet the bodys needs. The heart of raffia hookeri traditional food resources is an important source of nutrients. The adoption of a good regeneration and domestication strategy could make Raffia hookeriavailable for large-scale food exploitation and as a source of financial returns.
TROCAR SITE CLOSURE WITH OMENTAL PLUG INSERTION IN LAPAROSCOPIC BARIATRIC OPERATIONS: EFFICACY, SAFETY, AND OUTCOMES
Authors:   Department of Surgery, College of Medicine, Taif University, Taif, Saudi Arabia., M. Almalki Owaid ,   Department of Surgery, Alhada Military Hospital, Taif, Saudi Arabia.
Published: October 2024

Introduction:Trocar site herniation (TSH) remains a significant complication following laparoscopic bariatric surgery. Conventional closure techniques often prove challenging and may lead to inadequate closure, increasing the risk of TSH. This study aimed to evaluate the effectiveness and safety of a novel omental plug technique for closing trocar sites in laparoscopic bariatric surgery. Methodology:A retrospective study included 256 patients who underwent laparoscopic bariatric surgery (LSG, OAGB, or RYGB) between 2019 and 2023 at Armed Forces Hospital, Taif, Saudi Arabia. We used an innovative omental plug technique to close trocar sites â‰¥10mm. The primary outcome was the incidence of TSH within 12 months postoperatively, assessed clinically and with an ultrasonography examination. Secondary outcomes included wound infections, seroma formation, and reoperation for trocar site complications. Results:We observed no cases of TSH, indicating significant efficacy in preventing this complication. Other postoperative complications were minimal, with only one case (0.4%) of a superficial wound infection. Conclusion:In laparoscopic bariatric surgery, the omental plug technique demonstrated promising results in preventing TSH and reducing postoperative complications. Its ease of use, safety profile, and potential biological advantages suggest it may be a valuable alternative to traditional fascial closure methods. We warrant future larger, multicentric studies with longer follow-up to confirm these findings.
STUDY OF COAGULATION PROFILE IN TYPE 2 DIABETES MELLITUS
Authors:   Senior Resident, Department of Pathology, B.J. Medical College, Ahmedabad, India., Baladaniya Bhavana , Nanavati Monika ,   Associate Professor, Department of Pathology, B.J. Medical College, Ahmedabad, India., Goswami Hansa ,   Professor and Head of Department, Department of Pathology, B.J. Medical College, Ahmedabad, India.
Published: October 2024

Introduction:Diabetes mellitus is a chronic condition which has high risk for microvascular and macrovascular comorbidities by the process ofbinding of glucose molecules tovariousproteinsinvolvedinthecoagulationmechanism. The current study was carried out to determine the coagulation profiles of type 2 diabetes mellitus patients in comparison with apparently healthy controls. Methods:This was a comparative cross-sectional study carried out atTertiary careteaching institute Ahmedabad. Platelet parameters were determined by using HoribaPentraXLRautomated Hematology analyzer, whereas coagulation analysis was done using ACLTOP300CTSFullyAutomatedCoagulometer. The descriptive and analytical analysis was performed using MicrosoftExcel and SPSS software. We used student t-testtoanalyzethedifferencebetweenthemeans.AP-valuelessthan0.05wasset forthestatisticalsignificancedetermination. Result: The mean PT, INR and APTT in the Diabeticcase group were 11.46Â±1.63,0.98Â±1.14and29.83Â±4.09respectively.Thereweresignificantdifferences (p value<0.05) in the PT, INR and APTT between caseandhealthycontrolgroups.The mean platelet count was 257.92Â±75.48 and the mean MPV was8.00Â±1.03. Conclusion: The present study revealed reduced values ofPT,INR,APTT and no significant differences in platelet countsand MPVbetweendiabeticpatients andhealthycontrols.Thus,thefindingissuggestive of hyper- coagulable tendencies of diabetic patients compared to controls.
REVIEW OF LITERATURE ON NANOSCALE TOPOGRAPHIC MODIFICATION, MAGNETIC NANOPARTICLES, AND THEIR ROLES IN OSSEOINTEGRATION AND BONE TISSUE ENGINEERING
Authors: Y. Nelogi Santosh
Published: October 2024

Here, we will review together the roles of nanoscale modification of titanium substrates and use of magnetic nanoparticles in osseointegration and bone tissue engineering. The technological advances in nanotechnology that has been achieved create new measures to increase the implants-biological systems for an optimal osseointegration through improving important cell-specific functions. We systematically review nanoscale surface modification techniques of titanium implants, covering their physicochemical properties, influence on cellular behaviors and clinical relevances. The report also lengthy discusses the clinical applicability of magnetic nanoparticles for drug and gene delivery systems, targeted cancer therapy as well bone tissue engineering regulting their intrinsic superparamagnetism properites, biocompatibility with other therapies etc. We present detailed review of these technologies and their potential applications in clinical settings.
LEVEL OF STRESS LEVELS AMONG THE SCHOOL GOING STUDENTS AND COPING MECHANISMS: A CASE STUDY AT SELECTED SIX DIFFERENT SCHOOLS
Authors:   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Vakdevi V. , Yasaswini R. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Rupavathi M. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Sai Sampath T. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Daswanth P. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Sathya Gayathri K. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Meghana Deepthi G. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Sivaramakrsihna K. ,   Department of Computer Science and Engineering, Lingayas Institute of Management and Technology, Madalavarigudem, Vijayawada-521212, India., Chandra Sekhar B. ,   Department of Chemical Engineering, RGUKT RK Valley, Iddupulapaya, Vempalli, YSR Kadapa-516330, India.
Published: October 2024

Stress is the state of worry or mental situation caused due to the situations that everyone faces in everyday life, sometimes it seems to be minor, however, shows an unidentified impact. The present generation is witnessing the stress as a part of life and unavoidable. The main objective of this study was to study and understand the stress levels of the current generation students, particularly, school going students, as they will become the roots of the future. This study was also aimed at studying the relationship between stress and coping strategies adopted by the students and propose appropriate stress coping mechanisms, with respect to the schools visited. The results suggest that there is a need for the schools to operate hybrid-counseling centers for the students apart from their parents support to provide necessary support in effectively handling the stressful conditions. The results further suggest that the teachers employ information and communication technology (ICT) tools to instill conceptual learning, ultimately aiming to minimize stress in the academics. Furthermore, it is also suggested that the schools should encourage the students and make it mandatory to implement yoga techniques, which would instill self-controlling techniques, discipline and help in combating the stressful conditions.
A DESCRIPTIVE STUDY TO ASSESS KNOWLEDGE REGARDING UMBILICAL CORD BLOOD BANKING AMONG WOMEN IN THE REPRODUCTIVE AGE
Authors: Shokeen Nancy , Kumar Amit , Gopal Krishna , K. Varghese Shaun , Kundu Vishesh , , Priyanshi , and Favour , Singh Smita
Published: October 2024

Umbilical cord blood stem cells are the name given to the blood remaining in the umbilical cord and placenta after childbirth. Umbilical cord blood has the potential to be a huge source of primitive hematopoietic stem and progenitor cells that can be used to reconstruct the hematopoietic system and restore immunological function in individuals who require treatment. A descriptive research methodology was adopted in this study and 100 reproductive age group women in Sharda Hospital were selected in the present study. Convenience sampling technique was adopted for the data collection. The information was gathered via a knowledge questionnaire, which was used to assess knowledge regarding umbilical cord blood banking. The result revealed that 30 women had poor knowledge, 63 women had moderate knowledge and 7 had knowledge about umbilical cord blood banking. The importance of umbilical cord blood banking information was given among selected 100 participating women via the help of a pamphlet to raise awareness of uses of umbilical cord bloodbanking.
CYBERSECURITY IN CLINICAL PRACTICE
Authors:   Professor, Amity College of NursingAmity University, Gurgaon., Gauba Anu
Published: October 2024

Cybersecurity is a concern for patient safety. Recent cyberattacks on healthcare facilities around the world have exposed the risks to patients: from treatment delays due to hospital and clinic closures, to the threat harm from personal data theft, to patient death. The recent Covid-19 pandemic has further increased cyberattacks against healthcare organizations. Frontline healthcare workers are often warned about the dangers of poor data management and advised to take precautions to ensure data security. However, many workers are overwhelmed by conflicting administrative priorities, cybersecurity risks go unnoticed.
EVALUATING THE MARGINAL DISCREPANCY AND SURFACE ROUGHNESS OF CAD - CAM MILLED VS 3D PRINTED PROVISIONAL CROWNS - AN INVITRO STUDY
Authors: Ravella Himabindu , Sruthi Mayakuntla Gnana , Tedlapu Satyendra , Ronaki Sunitha , Vasudha Kommu , Adduri Rajasekhar
Published: October 2024

Aims &Objectives: To evaluate Marginal discrepancy and Surface roughness of CAD-CAM Milled and 3D Printed provisional crowns after subjecting them to thermocycling. Materials and Methods: A stainless-steel metal die with ANSI/ADA specifications had been fabricated for the study. It was scanned with an intraoral scanner and the data was sent to VHF S5M CAD CAM milling and R3Pro printing machine. A total of 10 samples Milled Group A(n=10) and 10 Printed Group B(n=10) provisional crowns were fabricated from PMMA material using the scanned data. The temperatures for thermocycling are 37ÂºC and 60ÂºC. Each group is subdivided into two subgroups(n=5) based on thermocycling temperatures. The timeduration selected for Thermocycling was 7,14 and21 days. Marginal discrepancy was measured by using Stereomicroscope and Surface roughness was measured with Profilometer. Results: Marginal discrepancy values were greater in CAD CAM milled crowns(141.47 Âµm) than in Printed crowns(109.87 Âµm) at 60ÂºC after a time-period of 21days.Surface roughness values were higher in Milled crowns(3.915Âµm) than in CAD CAM Printed crowns(3.817Âµm) at 60ÂºC for a given time duration of 21days. One-way ANOVA statistical analysis was done. The mean marginal gap of CAD CAM Milled crowns was statistically significant than Printed crowns(p>0.05). Conclusion: Printed provisional restorationshad better Marginal accuracythan CAD CAM Milled provisional crowns. Surface roughness was higher in CAD CAM Milled crowns than in Printed provisional restorations.
Communication Strategies for Interdisciplinary Teams Through Design Thinking and Technology-Driven Personalized Learning in Higher Education
Authors: Zolotova Mariya , Xue Xinrong
Published: October 2024

The paper discusses how Design Thinking and Technology-Enhanced Learning can support multidisciplinary teams in Higher Education working on creative projects. In particular, it proposes the integration of Design Thinking and AI-driven technologies into educational methodology to improve communication, engagement, personalized learning, and interactivity of students. The results of this approach are to address the challenges of Higher Education consisting in students’ assessment of the learning process, developing their creativity, critical thinking, and problem-solving skills. This educational project is designed in collaboration with the Department of Industrial Design and the Learning Mall at Xi’an Jiaotong-Liverpool University. The methodology includes a literature review on Design Thinking and analysis of surveys from the Design School students at Xi’an Jiaotong-Liverpool University and the AI assistants. Dynamic tools such as Articulate Rise 360 and AI have made it possible to visualize concepts and create interactive content for learners. The results include two educational prototypes that introduce a new thinking model to Design Thinking methodology and share experiments with interactive technological features. Applying this approach, teachers can create an environment conducive to the development of skills needed in the 21st century.
From bibliography to understanding: water microbiology and human health
Authors: Chen Shan , Ding Yuanzhao
Published: October 2024

Water is crucial for human health, yet its microbial composition bears significant ecological and health implications. This research utilizes bibliographic methodology, amalgamating data from the Web of Science, and the VOSviewer software to scrutinize a selection of 1,000 seminal articles. It comprehensively delineates (1) the pivotal microorganisms prevailing in aquatic settings, (2) the intricate mechanisms through which microorganisms wield influence over water quality, and (3) the multifaceted repercussions on human health and well-being stemming from these microorganisms. Through this scholarly exploration, the paper illuminates the intricate interplay between water, microorganisms, and human health, providing valuable insights for policymakers, researchers, and health practitioners. Understanding these dynamics is of paramount importance for maintaining both the ecological balance of aquatic systems and safeguarding the health of communities reliant on these resources. This study thus contributes to a deeper comprehension of the intricate relationship between water quality, microorganisms, and human health.
Analysis of water losses in seven small and medium-sized water distribution networks in the south region of Cameroon (Central Africa)
Authors: Dang Mvongo Victor , Defo Celestin , Nguema Paul Fabrice , Efon Boniface , Ondigui Mbeyi Jeanne Gabriella
Published: October 2024

This paper analyzes and evaluates water losses in seven small and medium-sized water supply networks (WSN) in the south region of Cameroon. Data was obtained from the regional delegation of Camwater for the south region and analyzed using a variety of indices, including the failure intensity index, the unit coefficient of water loss, the real leakage balance (RLB) index, the non-revenue water index (NRW), and the infrastructure leakage index (ILI). Results indicate that the cumulative volume of NRW in all the WSN was 7.3 million m3, which costs the water utility about 2.4 billion FCFA (or 4.4 million USD). The failure intensity index didn't perform well for all the WSN, ranging from 0.77 to 30.07 failures/km/year, leading to the conclusion that the WSN studied are not technically in good condition. Only the Ambam WSN performed well in terms of unit water loss. Findings also indicate that the RLB didn't perform well in all the WSNs, ranging from 27.31 to 2,916.30 L per connection per day. The ILI ranged from 0.02 to 122.65, showing that there is a need for better pressure management, active leakage control, and network maintenance. However, the data used in this study were weak and of low reliability, so the figures shown are just ‘guesstimates.’
Nickel (II) removal from real electroplating wastewater in an electrocoagulation reactor: parametric optimization by response surface methodology
Authors: Mahtab Md Azam , Bari Asma , Khan Salman , Ahteshaam Mohd , Khan Saif Ullah , Farooqi Izharul Haq
Published: October 2024

Electrocoagulation (EC) process was successfully applied and optimized for the removal of nickel (Ni) from real electroplating wastewater to achieve higher removal efficiency with low energy consumption. In the present study, an electrocoagulation reactor employing iron electrodes was set up for the experimental work. Response surface methodology (RSM) for a four-factorial central composite design (CCD) was applied to study the effects of process parameters on removal efficiency and energy consumption. Maximum Ni(II) removal efficiency of 95.16% was attained on optimization at an applied current of 0.31 A, an initial nickel concentration of 10 ppm, an application time of 18 min, and a pH of 7 along with the energy consumption of 0.443 Wh/g. With the help of the obtained three-dimensional (3D) plots, the interaction between the process variables was evaluated. By analysing the variance (ANOVA), the generated models were successfully validated.
Enseñanza inicial de la reanimación cardiopulmonar básica en escolares por enfermería: estudio piloto controlado
Authors: Cano-Rodríguez Luz Dary , Carreño-Moreno Sonia , Arias-Rojas Mauricio
Published: October 2024

Introducción: el aprestamiento y preparación de las personas para actuar en situaciones de emergencia como el paro cardiaco es crucial para aumentar la supervivencia de quien lo padece. Objetivo: describir la aceptabilidad, experiencia de participación y efectos potenciales de la implementación de la intervención “UN Salvavidas Kids” en escolares . Método: se realizó un ensayo piloto controlado fase II, de grupos paralelos, con seguimiento 1 semana post-intervención. El grupo experimental recibió la intervención “UN Salvavidas Kids”. Se evaluó la aceptabilidad y experiencia de los niños con la intervención a través de un cuestionario de satisfacción. Para evaluar el efecto potencial de la intervención se utilizaron los cuestionarios “Conocimientos teóricos” y “Habilidades prácticas”. Resultados: participaron en total 80 niños. Los resultados indicaron que la aceptabilidad y experiencia global de los niños con la intervención fue del 100% y 96% respectivamente. El efecto potencial de la intervención demostró una diferencia estadísticamente significativa en el nivel de conocimientos teóricos (4,5-vs-2,0) y en las habilidades prácticas (5,0-vs-1,0) entre el grupo experimental y el grupo control. Conclusiones: de acuerdo con los resultados de la aceptabilidad, experiencia con la intervención y efectos potenciales, la intervención puede ser reproducida en investigaciones futuras a gran escala.
Promoción de la vacuna contra el virus del papiloma humano
Authors: Flórez-Escobar Isabel Cristina , Quemba-Mesa Mónica Paola , Vargas-Rodríguez Leidy Yemile , Cortina-Huertas Natalia Michell , Parra-Flórez María Camila
Published: October 2024

Introducción: el virus del papiloma humano (VPH) es una infección viral que causa crecimientos en la piel o membranas mucosas y puede ocasionar cáncer. Objetivo: analizar las estrategias educativas utilizadas por el personal de salud para promocionar la vacuna contra el VPH. Método: se diseñó un estudio cualitativo con muestreo por saturación teórica. La muestra estuvo conformada por siete participantes del sector salud. La información se recolectó mediante entrevista semiestructurada y analizada a través del Software ATLAS. Ti. 8.0. Resultados: se obtuvieron seis categorías: Efectividad de las estrategias educativas utilizadas para la promoción de la vacuna contra el VPH, influencia de las estrategias educativas en el incremento de cobertura de la vacuna contra el VPH, población objeto a quien se dirigen las estrategias para la promoción de la vacunación contra el VPH, estrategias para la promoción de la vacunación contra el VPH, conducta promotora de salud ante la vacunación contra el VPH, y barreras para la promoción de la vacunación contra el VPH. Conclusiones: las estrategias educativas incluyen la educación digital, físico visuales y los medios de comunicación. Los procesos educativos posibilitan a la población cambiar su percepción, aceptar la vacuna, y, por ende, facilitan el aumento de la cobertura.
WPŁYW WOJNY NA UKRAINIE NA BUDOWANIE ODPORNOŚCI UNII EUROPEJSKIEJ
Authors: Kułaga Łukasz
Published: October 2024

Odpowiedź na wojnę na Ukrainie jest swoistym „testem” dla UE. W rezultacie opowiedzenia się po stronie ofiary agresji nastąpiło znaczące ograniczenie współpracy gospodarczej z Rosją, które wpłynęło na większość obszarów działalności UE. W konsekwencji, podejście UE do tego konﬂiktu może rzutować na funkcjonowanie całego projektu integracyjnego. W tym kontekście wojna na Ukrainie zwiększyła znaczenie czy wręcz upowszechniła odwołanie do koncepcji odporności w prawie UE. „Odporność” okazała się koncepcją pojemną i przydatną w warunkach kolejnego (po COVID-19) kryzysu, którego doświadczyła UE. Bez wątpienia wartością tej koncepcji jest dynamiczny charakter, jako zdolności do dostosowania, adaptacji w zależności od okoliczności. Budowa odporności w wymiarze wewnętrznym, w tym w zakresie kluczowych obszarów gospodarczych, może mieć również istotne znaczenie w zakresie zdolności UE do wsparcia Ukrainy. W dłuższej perspektywie budowanie odporności gospodarczo-społecznej przez UE może być skutecznym instrumentem nie tylko dla uniezależnienia się gospodarczego od Rosji, lecz także zmniejszenia tego uniezależnienia od Chin.
ODNAWIALNE ŹRÓDŁA ENERGII W KONTEKŚCIE ZAGROŻEŃ, ZADAŃ JEDNOSTEK SAMORZĄDU TERYTORIALNEGO I PLANOWANIA PRZESTRZENNEGO
Authors: Człowiekowska Joanna
Published: October 2024

W obliczu ujawnionych ostatnio zagrożeń wywołanych wojną na Ukrainie, kryzysem energetycznym i paliwowym, zanieczyszczeniem środowiska ujawnia się znaczenie i potencjał odnawialnych źródeł energii. W prawie administracyjnym kwestia ta może być analizowana z różnych perspektyw. W tym opracowaniu przedstawiono problem uwzględniania odnawialnych źródeł energii w zadaniach samorządu terytorialnego oraz w planowaniu przestrzennym.
ANDRÉS BELLO AND THE CHILEAN CIVIL CODE: CORNERSTONES OF THE PRIVATE LAW SYSTEM OF LATIN AMERICA
Authors: Olszówka Filip
Published: October 2024

This article describes the international inﬂuence of the 1855 Civil Code of the Republic of Chile, presenting the geographical extent of its impact, the reasons for its popularity, and the ways in which it was received. The basic idea behind this Code was its Pan-American approach, which was a key feature of the worldview espoused by its Venezuelan maker Andrés Bello, who compiled the Code for the Republic of Chile. To compose his Code and create the foundations of an integrated Pan-American identity, Bello combined the features shared by all the ex-Spanish colonies in South America, that is the Castilian culture and legal tradition, with the revolutionary inspiration of the independence movement of his times. Most of the countries in the region adopted Bello’s Code, either in part or in its entirety, and many are still using its legacy today. Moreover, the inﬂuence of Bello’s Civil Code transcended the borders of the South American continent, reaching other former Iberian colonies and even as far afield as Japan.
‘LEGIS ACTIO SACRAMENTO IN REM’ AS A RITUAL
Authors: Novák Marek
Published: October 2024

A ritual can be characterised as a form of conduct based on traditional and established rules. The basic purpose of its use is to confirm the validity of a particular action. Ritual consists of a set of precisely prescribed formal gestures, words or even movements. Undoubtedly, in legal practice the largest use of ritual and formal conduct is in procedural law, which is full of ritual formulas. To some extent, this is true of contemporary legal orders, but it is absolutely self-evident when we look at the earliest extant records of the ancient Roman process of legis actio sacramento in rem, which is described in detail in Gaius’ Institutions. This strictly formal procedure was fully ritualised and based on the parties using prescribed oral formulae. In many cases, the words and gestures could have had a constitutive character, provided they were performed in the prescribed manner. However, this was undoubtedly true of legal actions derived from civil proceedings, for example, in iure cessio, a form of transfer of ownership in which the transferor and transferee merely pretended to conduct legal proceedings in order to achieve a diﬀerent kind of objective, transfer of ownership. An addictio with constitutive eﬀect transferred the property to the transferee and could therefore be considered a performative utterance as defined by J.L. Austin.
UCHWAŁA W SPRAWIE WSTRZYMANIA REALIZACJI PRZEDSIĘWZIĘCIA – ASPEKTY USTROJOWE I PROCEDURALNE
Authors: Pierzchała Ewa
Published: October 2024

Zasadniczym celem niniejszego opracowania jest analiza prawnej formy działania organu stanowiącego gminy w przedmiocie wstrzymania wykonaniaprzedsięwzięcia, o którym mowa w ustawie z 20 sierpnia 2009 r. o finansach publicznych, ze szczególnym uwzględnieniem trybu prowadzącego do zmaterializowania się woli organu. Poruszane zagadnienie skoncentrowane jest wokół problemów związanych z inicjatywą uchwałodawczą wobec tego aktu oraz przedmiotowym aspektem powiązania go z uchwałą w sprawie wieloletniej prognozy finansowej. Istnieje bowiem prawna możliwość stanowienia o realizacji przedsięwzięć w dwóch różnych aktach prawnych, przy czym nie ma wyraźnie określonego obowiązku, aby organy stanowiące zadbały o spójną treść tych aktów. Może wobec tego dojść do trudnej sytuacji powodującej negatywne konsekwencje dla jednostki samorządu terytorialnego w wymiarze finansowym. Opracowanie stanowi próbę wskazania najistotniejszych problemów w tym obszarze wraz z propozycją rozwiązania lub niedopuszczenia do ich zaistnienia.
A Liquid Band-Aid with Mesenchymal Stem Cell-Derived Exosomes for Wound Healing in Mice
Authors: Zhang Wei-Yuan , Meng Tian-Jiao , Hu Jia , Wen Li , Du Li , Cheng Xiao-Chen , Wang Li-Sheng , Xiao Feng-Jun , Lu Yu-Xin
Published: October 2024

Introduction/Objective:

This study aimed to examine the effect of a human umbilical
cord mesenchymal stem cell-derived exosome (hUC-MSC-Exo) liquid band-aid on wound healing
in mice.

Methods:

hUC-MSC-Exos were prepared from the supernatant via ion exchange chromatography.
The composition ratio of the chitosan liquid band-aid was optimized to form a film and
encapsulate hUC-MSC-Exo. The biological effects of chitosan exosome liquid band-aid on human
umbilical vein endothelial cells (HUVECs) were observed, and its anti-bacterial properties
were tested. BALB/c mice with back skin injury were randomly divided into chitosan exosome
liquid band-aid group (CS-Exo), chitosan liquid band-aid group (CS), and normal saline control
group (Con), and wound healing was evaluated post-treatment. Skin tissue samples posttreatment
were collected for H&E staining.

Results:

The hUC-MSC-Exo was prepared and characterized. The optimum conditions for film
formation were 1% chitosan solution and 15% poloxamer 407/poloxamer 188 (pH 5.0 ~ 7.0).
The chitosan exosome liquid band-aid promoted HUVEC proliferation and migration and markedly
inhibited Escherichia coli and Staphylococcus aureus growth in vitro. In vivo, the wound
healing rate in the CS-Exo group was higher than that in the Con and CS groups. Fourteen days
post-treatment, the wounds completely healed, and hair grew normally, which was consistent
with H&E results. Mouse weights in each group did not change significantly after administration,
indicating that the chitosan exosome liquid band-aid had no obvious toxic side effects.

Conclusion:

Local chitosan exosome liquid band-aid application can promote wound healing in
mice, and the mechanism could be related to hUC-MSC-Exo-induced vascular endothelial cell
proliferation and migration.
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment
Authors: Gini Ana Luisa Rodriguez , João Emilio Emilio , Lopes Juliana Romano , Da Cunha Pamela Souza Tada , Velasquez Angela Maria Arenas , Graminha Marcia Aparecida Silva , dos Santos Jean Leandro , Scarim Caue Benito
Published: October 2024

The expression and release of cysteine proteases by Leishmania spp. and their virulence
factors significantly influence the modulation of host immune responses and metabolism,
rendering cysteine proteases intriguing targets for drug development. This review article explores
the substantial role of cysteine protease B (CPB) in medicinal chemistry from 2001 to 2024, particularly
concerning combatting Leishmania parasites. We delve into contemporary advancements
and potential prospects associated with targeting cysteine proteases for therapeutic interventions
against leishmaniasis, emphasizing drug discovery in this context. Computational analysis using
the pkCSM tool assessed the physicochemical properties of compounds, providing valuable insights
into their molecular characteristics and drug-like potential, enriching our understanding of
the pharmacological profiles, and aiding rational inhibitor design. Our investigation highlights that
while nonpeptidic compounds constitute the majority (69.2%, 36 compounds) of the dataset, peptidomimetic-
based derivatives (30.8%, 16 compounds) also hold promise in medicinal chemistry.
Evaluating the most promising compounds based on dissociation constant (Ki) and half maximal
inhibitory concentration (IC50) values revealed notable potency, with 41.7% and 80.0% of nonpeptidic
compounds exhibiting values < 1 μM, respectively. On the other hand, all peptidic compounds
evaluated for Ki (43.8%) and IC50 (31.3%) obtained values < 1 μM, respectively. Further
analysis identified specific compounds within both categories (nonpeptidic: 1, 2, and 4; peptidic:
48-52) as particularly promising, warranting deeper investigation into their structure-activity relationships.
These findings underscore the diverse landscape of inhibitors in medicinal chemistry
and highlight the potential of both nonpeptidic and peptide-based compounds as valuable assets in
therapeutic development against leishmaniasis.
Signaling Pathways (TNF-α-NF-κB, TLR2-TLR4 as well as ROS-MDA) and Cardiac Damages during Cardiac Surgeries (Coronary Stenting, Permanent Pacemaker Implantations, Radiofrequency Ablations)
Authors: Li Xia , Zhao Yongjuan , Zhou Hualan , Hu Youdong , Chen Ying , Guo Dianxuan
Published: October 2024

Introduction:

The mutual activations of multiple signaling pathways are the key factors
in the development and progression of myocardial cell injuries.

Objective:

This research aimed to compare the different degrees of myocardial injury after coronary
stenting, permanent pacemaker implantations, or cardiac radiofrequency ablation and to investigate
the effects of the mutual activation of TNF-α/NF-κB, TLR2/TLR4, and ROS/MDA signaling
pathways on myocardial injury in elderly patients after coronary stents or permanent pacemakers
or radiofrequency ablation.

Methods:

We determined reactive oxygen species (ROS), malondialdehyde (MDA), toll-like receptor
2 (TLR2), toll-like receptor 4 (TLR4), nuclear factor kappa B (NF-κB), tumor necrosis factor-
α (TNF-α) and high-sensitive cardiac troponin T (hs-cTnT) as markers of myocardial injury in
patients.

Results:

The levels of ROS, MDA, TLR2, TLR4, NF-κB, TNF-α, and hs-cTnT were increased in
patients with permanent pacemaker implantations when compared to patients with cardiac radiofrequency
ablation (P < 0.01) at 6 months and were further increased in patients with coronary stenting
compared to patients with cardiac radiofrequency ablation and permanent pacemaker implantations
at 6 months, respectively (P < 0.01). This research confirmed that ROS, MDA, TLR2, TLR4,
NF-κB, and TNF-α predicted myocardial injury severity.

Conclusion:

Oxidative stress (ROS/MDA signaling pathway) may be linked to immune response
(TLR2/TLR4 signaling pathway) and pro-inflammatory response (TNF-α/NF-κB signaling pathway)
in myocardial injury, and ROS/MDA signaling may play a dominant role.
Structural Investigation and Hirshfeld Surface Analysis of 2-6-Dimethoxy-4-((2-Nitrophenylimin)Methyl) Phenol
Authors: Inac Hasan
Published: October 2024

Introduction:

The reaction between 4-hydroxy-3,5-dimethoxyenzaldehyde and 2-ni-troaniline has been discovered, and the final product has been identified such as 2-6-dimethoxy-4-((2-nitrophenylimin)methyl)phenol (C1).

Materials and Methods:

X-ray diffraction examination per-formed on a single crystal provided conclusive evidence regarding the structure. Crystallography reveals that the two molecules A and B that were enclosed within the asymmetric unit are struc-turally distinct from one another. C-H·O, N-H·O, and O-H·O bonding is primarily respon-sible for the crystal packing stability. H-O and off-set stacking interactions also contribute to the crystal packing's overall stability.

Results:

To do further research into the intermolecular interactions, the Hirshfeld surface analysis technique is utilized. It is possible to determine the partiality of the interatomic contacts to create crystal packing interactions by computing the improvement ratio for those contacts. In addition, computational research is carried out with the B3LYP/6-31G(d,p) model to determine the amount of energy that is required for molecular pairs to interact.

Conclusion:

The study concluded the roles those different kinds of interaction energy play in maintaining the stability of the molecular pair.
The Five Times Sit to Stand Test as a Tool to Assess Disability and Physical Capacity after Hospitalization for COVID-19
Authors: Kchaou Khouloud , Barkous Balsam , Rejeb Hadhemi , Chakroun Sahar , Chaker Asma , Jameleddine Saloua Ben Khamsa
Published: October 2024

Background:

Assessment of exercise tolerance should be an integral part of the follow-
up of COVID-19 survivors.

Objective:

We aimed in this study to investigate the correlation between the 5 Times Sit to Stand
Test (5STST) and the 6-Minute Walk Test (6MWT) and to determine their place in assessing exercise
tolerance and disability in COVID-19 survivors.

Methods:

This was a cross-sectional study that included 201 survivors of COVID-19. All patients
underwent a detailed medical questionnaire, assessment of disability by the Lawton scale, and sub-
-maximal exercise tolerance by 6MWT and 5STST. Our study population was divided into two
groups based on the Length of Hospital Stay (LHS) (<10 or ≥10 days).

Results:

Compared with the group with a LHS < 10 days, the group with prolonged LHS (≥10
days) had a significantly greater mean value of 5STST. In contrast, the mean values of 6-minute
Walk Distance (6MWD) and Minimal Oxygen Saturation (MOS) were significantly lower. A significant
correlation of 5STST with Lawton score (r = -0.373; p < 0.0001) and 6MWD (r = -0.563;
p < 0.0001) was also found.

Conclusion:

Our results showed that the 5STST was correlated with the 6MWD and Lawton
score. Hence, it could be proposed to assess physical capacity and disability, especially in patients
who had a prolonged LHS for COVID-19.
Exploring Rheumatoid Arthritis: Unraveling Signaling Pathways, Advancing Management, and Charting Future Perspectives
Authors: Bajaj Shalini , Rathee Sunny , Patil Umesh K.
Published: October 2024

Rheumatoid arthritis (RA) is a chronic autoimmune disorder in which inflammation
occurs in the synovial joint and synovial membrane, and in severe condition, it leads to erosion of
cartilage and bone. The etiology of RA is still indescribable; generally, RA is a multifactorial disease,
wherein complex interactions between patients and different factors such as environmental,
genetic, and epigenetic factors determine the overall risk of disease. RA is classified based on the
stage of disease. Treatment for RA is still a challenge for doctors and researchers. Effective
treatment for RA can be achieved by decreasing disease activity or reduction of RA to other patients
using currently available treatment options. This article gives a comprehensive perspective
of data regarding different signaling pathways involved in RA development, factors affecting RA,
stages of RA, and other treatments of RA. This article also suggests future research perspectives
that would be helpful for the development of RA treatment (medicine) with more efficacy, safety
profiles, and lower financial costs.