bluuebunny/crossref_metadata_2025 huggingface dataset:
Rancang Bangun Jaringan Internet di Kantor Desa Kerta
Authors: Bagaskara Aditya Caesar , Gede Suhartana I Ketut
Published: March 2021

Pada tahun 2018, Kantor Desa Kerta di desa Kerta, kecamatan Payangan, kabupaten Gianyar menerima bantuan desa digital dari Kementerian Komunikasi dan Informatika (Kominfo). Desa digital adalah program pemerintah pusat untuk mengembangkan komunikasi terutama daerah pedesaan yang masih terkendala   jaringan internet.  Program ini diharapkan bisa membantu warga desa Kerta untuk mendapatkan akses internet.

Masalah jaringan muncul pada bulan Januari 2019, dimana sinyal dari program bantuan desa digital menurun sampai tidak ada koneksi. Hal ini membuat pelayanan online dan akses internet warga di kantor desa Kerta menjadi terlambat. Oleh karena itu, perlu dilakukan penelitian mencari alternatif jaringan internet bagi kantor Desa Kerta.

Salah satu alternatif jaringan yang didapatkan adalah jaringan operator seluler, yaitu Telkomsel karena memiliki sinyal terbaik di area kantor Desa Kerta. Kemudian dilakukan pemetaan lokasi menggunakan google link planner, test kecepatan jaringan menggunakan situs speedtest dan rancangan sistem menggunakan hardware yang sudah ada dari program desa digital. Hasil yang didapat adalah jaringan internet 4G telkomsel dengan kecepatan unduh 24.18 mbps dan unggah 20.59 mbps

Kata kunci : pemetaan lokasi, kecepatan jaringan
The Application Of Augmented Reality in Introducing Temples in Denpasar
Authors: Mahendra Ida Bagus , Muliantara Agus
Published: March 2021

Over time, the situation has changed the mindset of the Hindu community, especially in Bali in carrying out their worship. People no longer come to the temple just to pray and go home, but they wanted to know more about the temple itself. Due to the influence of the current era which quickly eroded historical existence, many were interested in knowing information about the temples they visited. However, this information does not just exist in a temple. The, specific information is stored in the literature and part of it is known by the temple administrators so that the public must look for it to find out. Due to lack of references and time constraints, people often give up their intention. By using augmented reality (AR) technology this problem can be overcome. AR technology is able to project virtual objects as if they look real to the human eye. In this case, AR is used to display the temple model and information with interactive illustrations to help the community recognize the temple. Users only need to install the application on their smartphone device and scan the QR code provided, then the temple as an object shows up and information can be displayed immediately. This application applies multi-target marker-based AR so that each temple information is stored and ran on different markers. Based on testing using the blackbox method, the results show that the application can run smoothly on several different devices both in terms of device resolution, memory speed and processor.
Studio Apartement Ontology Domain Development
Authors: Kresnawan Lanang Ary , Adi Pramartha Cokorda Rai
Published: March 2021

Bali is one of the provinces in Indonesia with its capital in Denpasar. Bali is well-known as a tourism destination with its unique arts and culture. For people who go to Bali to continue their education or work on work projects, they definitely need a place to stay while in Bali. Not infrequently many of them choose to rent this studio apartement because the facilities offered are adequate for them to live in Bali. However, because many of them come from outside the island of Bali, they don't know where to look for places or locations that provide these services. Lack of information about places that provide this service is one of the problems faced. Therefore, ontology can be used to provide information related to studio apartement explicitly by using the semantic ontology approach, because ontology is able to handle more complex data and is able to apply data-links, so that data can be integrated into various systems that have similar domains. built has 9 classes, 4 object properties and 14 individuals.
Digital Forensic Analysis Of Michat Application On Android As Digital Proof In Handling Online Prostitution Cases
Authors: Mahendra Kadek Dwi Oka , Ari Mogi I Komang
Published: March 2021

Smartphone technology and the Internet are very popular lately, especially with various features, one of which is instant messaging. But behind it all, instant messaging like MiChat is very vulnerable to becoming a crime, one of which is Online Prostitution. To follow up on Online Prostitution activities, it is necessary to carry out mobile forensics to find evidence which is then given to be given to the authorities. This study uses the MiChat application as an online prostitution media, and uses the National Institute of Justice (NIJ) method which has five basic stages is, preparation, collection, examination, analysis, and reporting. This research uses MOBILedit Forensic Express, and SysTools SQLite Viewer.
Implementation of Backpropagation for Ulap-ulap Pattern Recognition
Authors: Dewi Ni Luh Yulia Alami , Santiyasa I Wayan
Published: March 2021

Ulap-ulap is one of the symbols used to indicate that a building has been carried out Mlaspas ceremony. Mlaspas is one of the ceremonies performed to purify and clean a building. Ulap-ulap itself consists of various types depending on the building where it is placed, for example the ulap-ulap placed on the Pelinggih building will be different from the ulap-ulap placed on the Bale building. So that the pattern contained in each type of Ulap-ulap is different. The purpose of this research is to be able to do pattern recognition on Ulap-ulap images. The method used in this study is Backpropagation, and for its implementation, the MATLAB 7.5.0 (R2007b) application is used. This study used 18 images of Ulap-ulap, including 15 training data and 6 test data. The stages of the process carried out are for Ulap-ulap pattern recognition, the first is data collection, then image processing, and finally the pattern recognition. Recognition of the Ulap-ulap image pattern with Backpropagation, resulted in an accuracy of 83.333%.
Case Based Reasoning And Naive Bayes Implementation In Laptop Purchasing Recommender System
Authors: Dharmawangsa I Gusti Ngurah Agung , Supriana I Wayan
Published: March 2021

Purchasing a new laptop will be difficult if we do not know what the ideal laptop specification for our needs. Especially with a wide selection of laptops. From this problem, system that can give a recommendation to choose the right laptop based on purchaser’s specification choice is needed. This research using two method, Case Based Reasoning and Naive Bayes. The concept of Case Based Reasoning is the process of solving new problems based on the solutions of similar past problems, While Naive Bayes assumes that the presence of a particular feature in a class is unrelated to the presence of any other feature. Naive bayes will be implemented in retrive process of case based reasoning. The recommender system utilizing 7 feature, Kecepatan Processor, Kapasitas Ram, Tipe Grafis, Ukuran Layar, Ukuran Harddisk, Kecepatan Layar, and Harga. The percentage of respondents who said the system was successful in providing the right recommendations was 70 percent of the total respondents.
Terompong Basic Tone Synthesis with Frequency Modulation Method
Authors: Pratama I Gede Erwin Winata , Putri Luh Arida Ayu Rahning
Published: March 2021

Terompong is a type of gamelan in Bali Province. This gamelan is commonly used in traditional ceremonies in Bali, especially the Dewa Yadnya and Pitra Yadnya. The terompong are striking instruments, where the bat is made of wood. The terompong is also a two-octave musical instrument composed of 10-12 small metal gong blocks. The gong blocks are arranged parallel, which makes the gong difficult to carry and has to stay somewhere if someone want to play. Of course, with this situation people find it difficult to learn the terompong because they are quite large and heavy. This problem could be solved by replace the original terompong with synthetic terompong. The synthesis referred here the synthesis of sound. In performing sound synthesis, the method used is Frequency Modulation (FM). The result of the synthesis carried out where the difference between fundamental frequency of the original tone and the synthesis tone is almost close to zero. The sound produced almost follows the original sound, but it can't follow the sound of metal being hit with a wooden club.
Sentiment Analysis of Tribal, Religion, and Race with LIWC
Authors: Utomo Prasetyo Adi , Karyawati AAIN Eka
Published: March 2021

During this pandemic, social media has become a major need as a means of communication. One of the social media used is Twitter by using messages referred to as tweets. In Indonesia itself, there are various tribes, religions, and races in their society so the use of these names is also become commonly used. However, sometimes, the use of the name is followed by negative sentiment that used to insult and aimed at an individual or group. To filter that kind of tweets, a sentiment analysis was performed with LIWC method that divides tweets into 3 classes of positive, neutral, and negative. From the sentiment analysis that has been performed, the average score for precision is 69.62%, recall is 70%, and f-measure is 69.81%
Ensemble Model of Precipitation Change Over Indonesia Caused by El Nino Modoki
Authors: Brasika Ida Bagus Mandhara
Published: March 2021

The aim of this research is to understand the impact of El Nino Modoki into Indonesian precipitation and how ensemble models can simulate this changing. Ensemble model has been recognized as a method to improve the quality of model and/or prediction of climate phenomenon. Every model has their own algorithm which causes strength and weakness in many aspects. Ensemble will improve the quality of simulation while reducing the weakness. However, the combination of models for ensembles is differ for each event and/or location. Here we utilize the Squared Error Skill Score (SESS) method to examine each model quality and to compare the ensemble model with the single model. El Nino Modoki is a unique phenomenon. It remains debatable amongst scientists, many features of this phenomenon are unfold. So, it is important to find out how El Nino Modoki has changed precipitation over Indonesia. To verify the changing precipitation, the composite of precipitation on El Nino Modoki Year is divided with the composite of all years. Last, validating ensemble model with Satellite-gauge precipitation dataset. El Nino Modoki decreases precipitation in most of Indonesian regions. The ensemble, while statistically promising, has failed to simulate precipitation in some region.
Computational analysis by molecular docking of thirty alkaloid compounds from medicinal plants as potent inhibitors of SARS-CoV-2 main protease
Authors:   Department of Chemistry, Faculty of Sciences, University of Kinshasa, P.O Box 190, Kinshasa XI, Democratic Republic of Congo, Kuhana A Tunga , Kilembe Jason T. , Matondo Aristote , Yussuf Khamis M. , Nininahazwe Lauraine , Nkatu Fils K. , Tshingamb Milka N. , Vangu Emmanuel K. , Kindala Junior T. , Mihigo Shetonde O. , Kayembe Sungula J. , Kafuti Yves S. , Clement Agboyibor , Taba Kalulu M.
Published: March 2021

Year 2020 has been highly affected by the COVID-19 outbreak. The urgent need for a potent and effective drug for the treatment of this malignancy put pressure on researchers and scientists worldwide to develop a potential drug or a vaccine to resist SARS-CoV-2 virus. We report in this paper the assessment of the efficiency of thirty alkaloid compounds derived from African medicinal plants against the SARS-CoV-2 main protease through molecular docking and bioinformatics approaches. The results revealed four potential inhibitors (ligands 18, 21, 23 and 24) with 12.26 kcal/mol being the highest binding energy. Additionally, in silico drug-likeness and ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) properties for the four ligands showed a good predicted therapeutic profile of druggability, and fully obey the Lipinski's rule of five as well.
Effects of Black Vinegar and Niacinamide on LPS-Induced Inflammation on Human Keratinocytes
Authors:   Theraderm Co., Ltd. R&D Department, 10-6, Yeondong-daero 86-gil, Gangnam-gu, Seoul 135-502, South Korea, Park Ji Eun , Kim Young Mi
Published: March 2021

In this study, the effects of black vinegar (BA) and niacinamide on lipopolysaccharide (LPS)-treated human keratinocytes, HaCaT cells, were investigated. First of all, BA and niacinamide have no cytotoxicity in HaCaT cells even at high concentrations. LPS treatment triggers the phosphorylation of p38 mitogen-activated protein kinases (MAPK) and the expression of inflammatory enzymes, iNOS and COX-2. In contrast, BA and niacinamide weakened the expression of LPS-induced COX-2 and iNOS. Based on the results, we concluded that BA and niacinamide have effective anti-inflammatory properties in HaCaT cells. Therefore, BA and niacinamide may be used as new alternative treatments for inflammatory skin diseases. Keywords: Black vinegar, HaCaT cell, Inflammation, Keratinocytes, Liposaccharides, Niacinamide
Variations in tick-borne disease incidence rate by rural-urban county classification
Authors:   Department of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA, Omodior Oghenekaro , Kaukis Nicholas
Published: March 2021

Background: Surveillance data of tick-borne disease (TBD) incidence in the United States are compiled at the county level, yet few studies have classified TBD risk using established county classification systems. Objective: Determine if significant differences in TBD incidence rates exist between Indiana counties based on population size classification (i.e. urban, rural, and rural-mixed). Methods: County TBD data for the period 2009 to 2016, were obtained from the Epidemiology Resource Center at the Indiana State Department of Health. Using the 2010 decennial population census, we normalized TBD counts to derive incidence rates per 1,000 population. We classified Indiana counties as either rural, rural-mixed, or urban based on population size. We used Kruskal-Wallis nonparametric test to determine if median TBD incidence rates differed between urban, rural, and rural-mixed urban counties. We used choropleth maps in ESRI ArcGIS to display TBD incidence rate by county classification. Results: Kolmogorov-Smirnov pairwise comparisons test results, revealed no evidence of a difference in TBD incidence rates between rural, rural-mixed, and urban counties (p≥ 0.1208 ± 0.0065). Furthermore, Kruskal-Wallis test showed no evidence of a difference in the median TBD incidence rates by county classification (p = 0.9754). Higher TBD incidence rate counties occur in the western region, while lower rate counties occur in the eastern region. Although no differences exist in incidence rates by county classification, the two highest incidence rates were recorded in rural counties. Conclusion: A classification of Indiana counties based on population size is inadequate in identifying counties with a greater or lesser risk of TBD incidence. For a better understanding of county population-level TBD risk, future studies should aim at obtaining and exploring TBD incidence data at more granular, sub-county population levels such as zip codes, census- blocks and tracts.
Utilization of Construction and Demolition Waste Along with Fly Ash waste in Preparing Non-Autoclaved Aerated Concrete
Authors:   School of Environmental Science and Engineering, Donghua University Shanghai 201620, China, Wei Qunshan , Panhwar Kashif Ali , Nadeem Zuhair , Zhang Kai , . Bilal , Shen Zhemin
Published: March 2021

China’s construction industries are rapidly increasing, and with that generation of Construction and Demolition waste is also growing, and another side industrial waste such as fly ash produced by a thermal power plant, Associated environmental issues, it is essential to utilize in any form; Studies by concrete experts have indicated the feasibility of suitably handling and recycling such waste in new concrete, mainly for basic-level applications. Non-autoclaved aerated concrete is a lightweight substance that could be used as substitute building materials; it is generally made up of raw materials such as Cement, quicklime, gypsum, sand, and expansion agent like an aluminum powder; in this study, 40% waste utilized, Construction and demolition waste (5%,10%,15%,20% ………40%) and Fly ash (35%,30%,25%,20%......0%) accordingly, while expansion agent maintained constant at 0.06%. The compressive strength of the final material checked after (7,14,21 and 28 days) respectively, obtained maximum strength after 28 days; this study goals to design a low cost, Non-autoclaved aerated concrete material and to reuse the waste produced from different sectors, mainly from the construction sector Keywords: Non-Autoclaved concrete, Lightweight concrete, Eco-friendly, Construction and Demolition waste, Fly ash
Chitral Gol National Park; A paradise or threat for biodiversity conservation and socio-economic conditions of local societies
Authors:   College of Environmental Science and Engineering, Donghua University, Shanghai 201620, China, Jun Wang , Noman Muhammad , Ullah Sajid , Ali Kokab Saba , . Bilal , Khan Faisal , Tasleem Rabia , Ahmad Javed , Haq Izhar Ul , Emiliya Hamidova , Sahak Kawoon , Mushwani Hayatullah , Ullah Zakir
Published: March 2021

The current study was conducted to investigate the Chitral Gol National Park, as a bliss or risk for biodiversity safeguarding and socio-economic situations of regional people in the park region. The Chitral Gol National Park indicates a vital part in the improvement of the socio-economic situation and also in the management of the biodiversity in park area. The key aim of the park area is generally to enhance the societies’ link in the park area for its better management and conservation through community-based conservation. For this aim, 160 open ended questionnaires were equally distributed and collected in the park area. Results revealed that the local public much satisfied from the park area. 11 villages openly profited from the park area in case of cash, employments and wood fuel etc. The local public greatly concerned in the management of park area. The ecological profits from park were reported well. The administration maintenance was noble in the park area and show energetic role in the management of plantation, flora cover, fauna species etc. Public education and awareness about park areas via education, workshops, seminars, walk campaign, and local government must take obligatory stages for their safeguard and management. Keywords: Chitral Gol National Park, Local Community, Biodiversity Conservation, Socio-economic Conditions, Protected areas
Phytoremediation of contaminated soil Lead and Cadmium by Brassica júncea (L.) Czern plant
Authors:   College of Environmental Science and Engineering, Donghua University, Shanghai 201620, China, Wei Qunshan , . Bilal , Noman Muhammad , Shen Zhemin , Ali Kokab Saba , Ullah Sajid , khan Faisal , Panhwar Kashif Ali , Emiliya Hamidova , Tasleem Rabia , Ahmad Javed , Haq Izhar Ul , Subhanullah Muhammad , Ullah Zakir
Published: March 2021

Many remediating strategies are used for polluted soils, however, but mostly the essential phytoremediation is a less expensive, organically satisfying technique that is generally reasonable for various countries. Pot tests were managed to dissect the Brassica júncea plant biomass cultivated on Pb as well as Cd polluted soils as well to survey its ampleness for the evacuation of Pb and Cd. Samples of picked plants developed at a blend of alluvial soil and sand were moved with vessel of pots the earth finishing extents as well allowed make with time regenerative development. Through acid digestion, Pb and Cd extraction was settled from the plant. Consequently, they were collected and afterwards examined for chosen metals through utilizing Atomic Absorption Spectrometry (AAS). Generally, the current examination results demonstrated that no hyperaccumulators of Pb as well Cd were recognized in the region. Body parts of the plant were categorized as Pb low accumulators, moderate accumulators and excluder, as well as Cd low accumulator, excluder. Additionally, Cd concentration was high up than the allowable range in species of plant. In plants, allowable range of Pb and Cd is 0.2 - 20 and 0.1 -2.4 mg kg – 1. In Brassica júncea plant the Pb as well Cd both were no hyperaccumulators. Hence, this local plant had the suitable ability to use for phytoremediation of contaminated soils around the Hayatabad Industrial area, Peshawar. All experimental Results demonstrated that from the medium of soil by Brassica júncea (L.) Czern plant the maximum lead and cadmium removals were 94 % and 94.26 %, respectively in the open environment, while in the control environment this removal was 82 % for Pb and 93.16 % for Cd .The present research work observes that brassica júncea (L.) Czern plant was more helpful for Cd take-up contrasted with Pb, and thus it is capacity we suggest Pb as well Cd for remediation from polluted soils. Keywords: Lead, Cadmium, Contaminated soil, Removal
Anti-Diabetic Potential of Anti-Oxidant Compounds "Riboflavin, Flavin Mononucleotide and Flavin Adenine Dinucleotide" with High Therapeutic Potency through Inhibition of α-Amylase and α-Glucosidase Enzymes at Sub-Micromolar Concentrations
Authors:   Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran, Esmaeili Sajjad , Amoushahi Maryam , Barati Hamzeh , Ansari Mohabbat , Shafiee Soodabeh
Published: March 2021

Diabetes is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Inhibition of carbohydrate hydrolyzing enzymes leads to decrease in the absorption of glucose which is considered as one of the effective managements of diabetes mellitus. Vegetable, fruit, milk, and fish are good sources of riboflavin (RF) and vitamin B5 with versatile health benefits. The well-adapted structural features of these compounds for the inhibition/activation of enzymes include several available hydrogen bond (H-bond) acceptors and donors, flexible backbone, and hydrophobic nature. The substrates of α-amylase (α-Amy) and α-glucosidase (α-Glu), known as key absorbing enzymes, have functional groups (OH groups) resembling RF and vitamin B5. Therefore, the present study was conducted to evaluate the inhibitory properties of fliavin, RF, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD) and vitamin B5 against α-Amy and α-Glu. The median inhibition concentration (IC50) values for α-Glu in the presence of RF, FMN and FAD were determined 136.7±4.8, 235.4±5.2 and 78.9±3.4, respectively. The IC50 values α-Amy in the presence of RF, FMN and FAD were determined 165.6±7.1, 253.6±5.5 and 131.2±6.3, respectively. Moreover, the Ki values of RF were calculated as 14.2±1.8 and 18.6±1.7 µM for α-Glu and α-Amy in a mixed-mode. In addition, to communicate with the active site of α-Glu and α-Amy respectively, RF presented a binding energy of -8.1 and -7.3 kcal/mol, FMN -7.1 and -6.8, and FAD -10.3 and -7.8 kcal/mol. These antioxidant inhibitors may be potential anti-diabetic drugs, not only to reduce glycemic index, but also to limit the activity of the major reactive oxygen species (ROS) producing pathways. Key words: Riboflavin, hydrolyzing enzymes, enzyme inhibition, hyperglycemia Introduction
Production area and harvest date influence superficial scald incidence and ultra-structure of 'Suli' pear skin during long term storage
Authors:   Research Institute of Pomology, Chinese Academy of Agricultural Sciences, Wang Wenhui ,   Key Laboratory of Fruits Storage and Processing,Province Liaoning, Xingcheng 125100, Jiang Yunbin , Wang Zhihua , Guo Huangping , Jia Xiaohui , Tong Wei
Published: March 2021

The effect of production area and harvest date on the superficial scald incidence, ultra-structure of the pericarp, core browning, and related physical qualities of ‘Suli’ pears during storage period at 0 °C were investigated. ‘Suli’ fruits were harvested at Taigu and Linyi in Shanxi province of China over five different dates and then stored at 0±0.5 °C with 85-90% relative humidity for 120 or 200 days. Superficial scald was detected after 120 and 200 days of storage. Harvest date and production area significantly affected the incidence of superficial scald and the quality of 'Suli' fruits. Earlier harvest time was associated with increased incidence of superficial scald. Fruits picked at Linyi developed more severe superficial scald than fruits harvested at Taigu. Scanning electron microscope (SEM) revealed that the cuticle and wax layer of fruits from Taigu were thicker than those from Linyi after storage. The surface of earlier harvested fruits had less wax and more extensive cracking, lower pectin content, and damaged skin organization structure. The incidence of superficial scald in ‘Suli’ pears is dependent on the ultra-structure of these superficial layers, and differences may be driven by harvest date and location. Keywords: Production area, Harvest date, Superficial scald incidence, Ultra-structure, ‘Suli’ pear
Silver implantation on AISI 304 stainless steel surface using low-energy doses and the antimicrobial effect against Salmonella Enteritidis and Listeria monocytogenes
Authors:   Departamento de Ciências dos Alimentos, Instituto de Ciência e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (ICTA/UFRGS), Av. Bento Gonçalves, 9500, 91501-970 Porto Alegre, RS, Brazil, Kothe Caroline Isabel , Zilio Regina , Zamboni Tatiana Pacheco Soares , Aguzzoli Cesar , Casarin Leticia Sopeña , Tondo Eduardo César
Published: March 2021

Silver has antimicrobial properties and when implemented on the stainless steel surface can inactivate microorganisms and consequently prevent biofilm formation and cross-contamination of food. Therefore, in this study we evaluated the antibacterial properties of silver ions implanted on AISI 304 stainless steel surfaces using low-energy doses against Salmonella Enteritidis and Listeria monocytogenes, two foodborne pathogens. AISI 304 stainless steel coupons were treated using energy of 2 and 4 keV for silver implantation and simulations were performed to estimate its dose distribution. Coupons containing silver ions were contaminated with S. Enteritidis and L. monocytogenes and incubated at 25 °C for 1 and 24 h. Results demonstrated that 4 keV treatment were able to reduce S. Enteritidis, but not L. monocytogenes. However, the 2 keV treatment showed significant reductions of both pathogens and the depth profiles of surfaces treated with 2 keV of energy showed 3.5×1016 silver atoms/cm² implanted in up to 5 nm from the stainless steel surface. Silver implanted on stainless steel using low-energy doses demonstrated antimicrobial properties against foodborne pathogens and this strategy can be used to reduce adhered cells and biofilm formation in food industries. Keywords: bacterial adhesion, biofilm, foodborne pathogens, ion implantation, silver ions
Milk Cereal Drink Feeding Practices: A Descriptive Study Among Swedish Cohort of the IDEFICS Family Study
Authors: Hunsberger Monica , Ngwa Che Henry , Panneh Mamtuti , Eiben Gabriele , Rosén Maja
Published: March 2021

Background: Childhood overweight is an increasing public health concern and has recently been associated with the consumption of a traditional Swedish milk cereal drink (MCD). This study aimed to describe the consumption pattern of MCD among study participants in relation to the recommendations by the National Food Agency of Sweden. Method: A cross-sectional study among the Swedish cohort of the IDEFICS.Family (I.Family) study was conducted in 2013/2014. Swedish participants completed a questionnaire aimed at understanding the prevalence of consumption, timing, frequency, feeding modality and rationale for offering MCD. Results: Most children (74.7%) reportedly consumed MCD. Of those who consumed MCD, a large part of the participants consumed MCD two or more times a day with a high proportion of participants (87%) stating a preference for bottle-feeding. Keywords: Milk cereal drink, Obesity, Complementary food, Feeding practice, I. Family Study, Sweden.
Identification and Characterization of a Pseudomonas mosselii strain and its Antibacterial Function against Agrobacterium tumefaciens
Authors:   Key Laboratory of Plant Development and City College of Vocational Technology·Utilization of Ningbo, Ningbo Zhejiang 315199, China, Wang Zhilong ,   2 Ningbo Academy of Inspection and Quarantine, Ningbo 315012, China, Li Wen , Wang Jiaying , Jiang Xintong , Zhu Qianhui , He Yueqiu , Fu Tao
Published: March 2021

Agrobacterium tumefaciens is a gram negative bacterial that can infect a range of plants and result in root crown gall. A total number of 10328 bacterial strains were isolated from rhizosphere of cherry tree. One strain of LWB10 showed clear inhibition zone around the bacterial colony in YEB media inoculated with A. tumefaciens C58. Morphological, physiological, and biochemical characterization indicated that LWB10 belongs to member of the genus Pseudomonas. Results from the high-throughput matrix-assisted laser desorption/ionization biotypersmart system indicated that this strain had a score value of 2.247 relative to Pseudomonas mosselii. Also, phylogenetic analysis based on 16S rRNA gene sequence showed that strain LWB10 shared the highest similarity with Pseudomonas mosselii CIP 105259T. The antagonist strains also exhibit well in growth inhibition of other five A. tumefaciens strains. Coinoculation of LWB10 and plant pathogenic strain of A. tumefaciens CFCC1369 showed strongly inhibition of tumor formation in tomato stems. All the results demonstrated that the isolated strain is P. mosselii LWB10 and its antibacterial ability to A. tumefaciens may offer new way for management of crown gall disease in the future. Keywords: Agrobacterium tumefaciens, Pseudomonas mosselii, antagonist, biological control
O estresse dos profissionais de enfermagem em Unidades de Terapia Intensiva: uma revisão bibliográfica
Authors: De Souza Melina Rodrigues , Barros Pâmella Aparecida , Ribeiro Jussara Camila , Resende Márcio Antonio , De Souza Hélia Cristina , Calsavara Renata Angélica , Dos Santos Andréia Andrade
Published: March 2021

Objetivo: Consiste em descrever as implicações do estresse na rotina de trabalho dos profissionais de enfermagem nestas unidades. Revisão bibliográfica: Com as inúmeras demandas enfrentadas por enfermeiros em Unidades de Terapia Intensiva, muitos enfermeiros passam a lidar com o estresse, o que interfere no bem-estar, na saúde e no desempenho desses, destacando-se a ocorrência da Síndrome de Burnout, que, por sua vez, se manifesta por meio do esgotamento mental e físico. Diante disso, é importante que esses profissionais adotem estratégias que fortaleçam para o enfrentamento do estresse, consigam preservar sua saúde e desenvolver bem o seu trabalho. Considerações finais: É necessário e imprescindível a adoção de medidas alternativas em prol da saúde dos trabalhadores e da qualidade do trabalho. A aplicação das estratégias de enfrentamento pode ser eficaz no manejo do estresse por meio de intervenções preventivas e protetivas com os profissionais. O alcance da excelência na assistência ao paciente requer condutas e ações que viabilizem um processo dinâmico e sistematizado.
A reemergência do sarampo no Brasil associada à influência dos movimentos sociais de pós verdade, fake news e antivacinas no mundo: revisão integrativa
Authors: Almeida Hatus da Silva , Costa Sueli de Souza , Costa Izolda Souza , Junior Claudio Rogério Rocha
Published: March 2021

Objetivo: Analisar os trabalhos publicados envolvendo os recentes surtos de sarampo e sua relação com o fenômeno recente de pós-verdade, fake news e movimento antivacinas. Métodos: Revisão de literatura integrativa, nas bases de dados eletrônicas LILACS, PUBMED e SCIELO, com os seguintes descritores, em língua portuguesa: “sarampo”; “vacinação”; “notícias”; “recusa de vacinação” e “detecção de mentiras”, no período de 2013 a 2019. Foram empregadas etapas de combinações entre os descritores, em categorias, para a seleção dos artigos e análise. Resultados: Foram encontrados 3680 artigos, sendo 12 da base de dados SCIELO, 3639 no PUBMED e 29 no LILACS, que, após a aplicação dos critérios de exclusão, restaram 60 artigos. O Brasil aparece em três publicações (5% do total). Observou-se um crescimento linear entre as publicações, dos anos de 2013 a 2019. Considerações finais: A produção acadêmica mundial quanto ao tema, foi significativa no período, quando observado os componentes da ideia proposta de forma isolada, apontando alguns assuntos com maior ênfase que outros. Observa-se, entretanto, a necessidade de mais publicações envolvendo as temáticas de forma integrada, afim de que se possa estabelecer, ou não, associação dos termos na dinâmica causa-consequência.
Bronquiolite Respiratória associada à Doença Intersticial Pulmonar e Histiocitose das Células de Langerhans: estudo de caso
Authors: Negreiros Ricardo Andre Medeiros , Simas Bernardo Rosado Negreiros Gadelha , Rosado Victor José Negreiros de Sá , Nunes Giulia Palitot de Oliveira Lima , Amorim Pedro Paulo Feitosa , D'Assunção Luís Eduardo Negreiros , Queiroga Fernando José Pinho , D'Assunção Viviane Rosado Negreiros
Published: March 2021

Objetivo: Relatar um caso notável de Bronquiolite Respiratória associada à Doença Intersticial Pulmonar (RB-ILD) cursando com Histiocitose das Células de Langerhans (LCH). Detalhamento do Caso: Paciente masculino, 57 anos, obeso, sedentário, com carga tabágica de 80 maços-ano. Em consulta de rotina, realizou tomografia computadorizada de tórax (TC) que revelou pequenas opacidades nodulares de aspecto inespecífico, além do diagnóstico de enfisema pulmonar centrolobular. Após 8 meses, compareceu ao pneumologista com tosse persistente e sem alterações no exame físico. Feita nova TC, evidenciou-se múltiplas opacidades nodulares de contornos irregulares acometendo difusamente o parênquima de ambos os pulmões, predominando nos lobos superiores e médio, com suspeita de envolvimento neoplásico secundário. Feita biópsia pulmonar, observou-se infiltrado inflamatório nodular, com bordas irregulares, em distribuição peribronquiolar e subpleural, composto por histiócitos pigmentados e agregados linfoides em meio a fibrose. O parênquima adjacente revelou bronquiolite respiratória. O exame imuno-histoquímico revelou positividade para células CD1a+ em alguns nódulos. Os achados foram compatíveis com RB-ILD e LCH, sendo estas doenças de etiologia raras que se apresentam nos exames de imagem similares a outras afecções pulmonares. Considerações Finais: Por tratar-se de condições raras, é necessário que seja feita a devida investigação para se evitar diagnósticos incorretos e tratamentos inadequados.
Arthroscopic ankle arthrodesis – Surgical technique
Authors: Mangwani Jitendra , Afifi Hytham , Faroug Radwane
Published: March 2021

End-stage ankle arthritis causes significant pain, disability, and reduction in the quality of life. The common causes of ankle arthritis are post-traumatic (70%), secondary to rheumatoid arthritis (12%), and idiopathic (7%). Surgical arthrodesis of the tibiotalar joint is used to help alleviate the symptoms and signs of end-stage ankle arthritis. The first documented description of ankle arthrodesis is by Albert of Vienna in 1879 who reported curettage of the articular cartilage to enable fusion of the ankle joint. Since that time, this process has been refined significantly culminating in the introduction of arthroscopic ankle arthrodesis (AAA) by Schneider in 1983. AAA is now considered as the current gold standard to help achieve effective and predictable pain relief and improved function for patients who suffer with end-stage ankle arthritis.
Customized Attachment for Cheek Plumper: A Case Report
Authors: Vidushi Saxena  , Nikhil  Kumar Chaudhary  , Manisha Gulati  , Salil Pawah
Published: March 2021

The goals of replacement of teeth with a complete denture are not limited to only providing the patient with the ability to chew food comfortably. Due to the increasing demands and consciousness of the patients regarding esthetics, prosthodontist must emphasize on not just the function but also overall appearance of the patients.  The loss of support of the facial musculature is of great concern in treating completely edentulous patients. Sunken cheeks are one of the major consequences of flaccid facial musculature. The incorporation of cheek plumpers in the dentures has improved the appearance of patients with such conditions. They are noninvasive and straightforward to fabricate. Various attachments may be used for this purpose depending upon the case present. This case report involves 2 cases with different techniques for the attachment of detachable cheek plumpers.
Chemotherapy induced cardio toxicity with doxorubicin and cyclophosphamide in breast cancer patient - A case report
Authors: Jis Ann Maria  , Jina Raj  , Mukundan G  , Vysakh Visweswaran  , Aiswarya Mohan  , Ayana S Kumar  , Rajesh Thachathodiyl  , Remya Reghu
Published: March 2021

Breast cancer is the most commonly occurring neoplasm in women, which can be curable as well as can reduce the recurrence of cancer, with the help of various multidisciplinary approaches and thereby decrease the morbidity as well as mortality. Chemotherapy is a well-defined therapeutic approach for breast cancer, but cardiotoxicity is the most potential side-effect associated with chemotherapeutic drugs. Doxorubicin, along with cyclophosphamide, produces serious cardiotoxicity due to potential drug interaction. It is a case of a 63-year-old female patient post-menopausal with k/c/o type 2 diabetic Mellitus on medication. Clinically and radiologically, she was diagnosed with carcinoma left breast (IMC grade III, TNBC, CT2N0Mx). She underwent breast-conserving surgery (BCS) or lumpectomy without reconstruction. The HPE report suggestive of infiltrating mammary carcinoma NST grade 3. She was currently on adjuvant chemotherapy IInd cycle. Post chemotherapy, she was admitted with complaints of chest discomfort and chest pain. Screening ECHO showed grade I diastolic dysfunction and also the cardiac enzymes and cardiac marker troponins I was found to be elevated. She had undergone CAG for risk stratification. She was thought to have chemotherapy-induced cardiotoxicity associated with atypical chest pain and was advised medical follow up. Doxorubicin and cyclophosphamide-induced cardiac dysfunction and associated adverse events can be prevented or minimized with dose modification, use of cardioprotective drugs, identifying patient-related risk factors and regular cardiac monitoring of the patient receiving chemotherapy with doxorubicin and cyclophosphamide in breast cancer treatment.
Validated stability-indicating RP-HPLC method for simultaneous estimation of cilnidipine and chlorthalidone in tablet dosage form
Authors: Ashok B. Patel  , Amitkumar J. Vyas  , Shital Faldu  , Arvind N Lumbhani  , Nikunj J. Patel  , Nilesh K. Patel  , Ajay I. Patel  , Jayant R Chavda
Published: March 2021

A novel, simple, specific, accurate & precise stability-indicating Gradient reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed for simultaneous estimation of Cilnidipine & Chlorthalidone in tablet dosage form, validated as per ICH guideline. The separation was achieved on Inertsil ODS column (250 mm x 4.6 mm, 5 μm) in a gradient mode.  The mobile phase consisted of Methanol, 0.025 M Potassium dihydrogen phosphate Buffer pH 5.5 adjusted by 10% v/v Ortho Phosphoric Acid (50:50 v/v) (Solution A) and Acetonitrile, 0.025 M Potassium dihydrogen phosphate Buffer pH 5.5 adjusted by 10%v/v Ortho Phosphoric Acid (75:25 v/v) (Solution B), gradient programming for 20 min at 1 ml/min rate of flow and response was detected at 225 nm. The retention time was found to be 3.580 min and 12.606 mins for Chlorthalidone and Cilnidipine, respectively. The method is validated according to ICH guideline, which includes linearity, specificity, accuracy, precision and robustness. Linearity was obtained over the concentration range of 10-60 μg/ml for Cilnidipine and 6.25-37.5 μg/ml for Chlorthalidone, had a regression coefficient (r2) almost 0.9966. The % Recovery was found to be 99.63-100.59 % and 100.24-100.51 % for Cilnidipine and Chlorthalidone, respectively. The method was found to be specific enough to separate all degradation products from the active compound. Drug samples were exposed to various stress conditions like photolysis, oxidation, heat conditions, and hydrolysis (acidic and alkaline), there was no interference of any degradants and excipient in the determination of drugs so that methods can be successfully applied for routine QC analysis.
Distal Radius Measurements in Indian Population-An comprehensive Morphometrical Analysis
Authors: Gunalan  , Naveen Kumar
Published: March 2021

The four basic morphometrical parameters regarding the anatomy of the distal end of radius bone are radial inclination, palmar tilt/volar tilt, radial height (length) and ulnar variance. The management of various conditions such as fracture of the distal radius bone, designing of the distal radius plates and kinesiology utilize the parameters in the morphometrical measurement of the distal end radius. The goal of our study is to bring about the normalized values of the morphometrical parameters of the DER among the general Indian population for helping in designing the distal radius plates. The study was conducted in a tertiary care hospital in India. It was a single hospital based study. The views considered for the study were the true posteroanterior (PA) and the lateral view (with neutral rotation). The posteroanterior view was used for the measurement of radial inclination, radial length (height) and the ulnar variance. The lateral view helped in the accomplishment of the measurement of the palmar/volar tilt. The statistical analysis was done by Microsoft Excel 2007 (Data add in function was installed for the analysis of the collected data). The means of the morphometrical parameters was compared with the help of T-test. Two hundred (n=200) radiographs were included for analysis under this study. The mean value of radial inclination was 20.7 8 ° ± (SD) 3.45° [Range: 14.9-29.1°], palmar/volar tilt 10.99° ± (SD) 3.87° [Range: 1.8-18.6°], radial length/height 11.39 mm ± (SD) 1.97 mm [Range: 8.3-27.7 mm], and ulnar variance 0.90 mm ± (SD) 3.14 mm [Range: +0.70 to +3.70]. This study will lead for further researches in the analysis of the morphometrical parameters of the distal end of radius bone in the Indian population. For the clinical management of the injuries around the wrist joint the results of this study can be used as a reference standard to anatomically align the bones and the affected structures.
Potential Health Benefit Of Isoflavones
Authors: Vadivelan Ramachandran  , Bhargav Bhongiri  , Raju Bairi  , Raman Suresh Kumar
Published: March 2021

Isoflavones are bioactive compounds and structurally related to 17-β-estradiol  having mild estrogenic character also known phytoestrogen. These are available in more quantities in vegetables like green beans, soybeans, mung beans. In grains, they are available for the most part as glycosides, which are absorbed very poorly. It can behave as estrogen agonists or antagonist, by depending on the estrogenic level of endocrine, yet the action of isoflavones are complex because of numerous factors, for example, compound structures and mode of action. Though foods rich in isoflavones have become a centre of interest because of their beneficial effect on many health issues. In view of the appraisal of these illnesses by the action of isoflavones, it was fulfilled that the ability of isoflavones in the anticipation and management of different ailments generally results from their phytoestrogen antioxidant action. Isoflavones were called to as mysterious biological compounds that characteristic to forestall many major health issues. Intake of soy product has been connected to a decrease in rate or seriousness of long term illness, for example, heart disorder, breast and prostate malignancies, menopausal symptoms, bone disorder, so forth. This review discussed an overview of its health benefit on different human diseases.
A Study on Antibiotic Usage Pattern in Pediatric Population for Urinary Tract Infection
Authors: Divya V Nair  , Gopika S Kumar  , Remya Raghu
Published: March 2021

A prospective observational cohort study was conducted on 144 patients admitted with UTI for a period of 1 year and observed for the recurrence for next 1year. The objective was to study the antibiotic resistance pattern of uropathogens in UTI and to assess the antimicrobial utilization pattern in the pediatric ward of a tertiary care hospital. The confirmatory test used for UTI was urine culture. The most common causative agent for UTI was found to be Escherichia coli followed by Klebsiella. Antibiotic testing of E.coli and other isolates was done which showed greater sensitivity to meropenem and amikacin compared to other antibiotics tested. This isolates showed increasing resistance to commonly used antibiotics. Most of the children (74.31%) were treated with a single antimicrobial agent.  Cephalosporins (n  = 87; 60.41%) were prescribed to majority of the children, followed by Penicillin derivatives (n  = 42; 29.17%) and Carbapenems (n = 16; 11.11%). The percentage of antimicrobials administered by parenteral route was found to be 79.17%. The major problems encountered in the management are relapse of UTI and treatment failure.  Out of 144 children, 40 children had recurrent UTI. Among them for 25 children, antibiotics were not given according to the culture sensitivity pattern during their first UTI. Recurrent UTI can occur if  adequate antimicrobial therapy based on antimicrobial susceptibility test is not given during initial UTI. This demonstrates the need for rational use of antimicrobials and judicious prescribing. The implementation of antibiotic policy and treatment guidelines based on regional data on antimicrobial susceptibility of uropathogens with periodic assessment of the clinical pharmacist in the study area is recommended.
Role of upper gastrointestinal endoscopy prior to cholecystectomy to assess the postoperative outcome
Authors: Neethish K Paul  , Balamurugan R  , Athira Gopinathan  , Sivamarieswaran R
Published: March 2021

The aim of the study is to identify UGI pathologies in patients with cholelithiasis and association of these pathologies with a relief of symptoms in cholecystectomy patients. The study was conducted in 150 patients, who attended the surgical outpatient block or referred to our department from other departments and also known case of cholelithiasis by imaging studies. They were divided into a typical or atypical group based on their symptomatic presentation. UGI scopy was done on these groups, 2 days prior to surgery. Postoperatively patients were followed up on 7th, 21st and 42nd day and pain if any was assessed by NRS scaling method. Following results were noted. A female preponderance was seen (96 (64%)). Determining on age, 51 % of cases were seen among 31-50 years. UGI scopy revealed UGI pathologies in 22 among 92 (24%) patients who had typical symptoms of biliary colic, while 47 of 58 (81%) atypical presentations had UGI pathologies. The most common UGI pathology was gastritis and duodenitis (42 of 69 (61%)). Medical management was initiated for these pathologies prior to surgery. Postoperatively on 7th day 114 (76%) had no symptoms and 36 (24%) were symptomatic, of which 25 (69.4%) of them were UGI Positive preoperatively. Medical Management for their Gastrointestinal pathologies was continued and reviewed on 21st day of surgery which showed symptom relief in 31 of 36 patients (86.1%) and relief of symptoms in remaining 5 by 42nd day of surgery. Hence, this study recommend preoperative UGI scopy in cholelithiasis, which will help in postoperative management.