bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effectiveness of Mentoring Technique to Improve Self-Efficacy in English Language Learning of 7th to 9th-Grade Students with Visual Impairment at SLB A Yaat Klaten
Authors: Arifin Misbahul , Yusuf Munawir , Yuwono Joko
Published: August 2021

This study aims at investigating the effectiveness of mentoring technique to improve self-efficacy in English language learning of 7th to 9th-grade students with visual impairment at SLB A Yaat Klaten. This study belongs to experimental research using a pre-experimental design with one group pretest-posttest. The subjects in this study include 7th to 9th-grade students with visual impairment at SLB A Yaat Klaten determined using a saturated sampling technique. The research instruments were questionnaires with 20 favorable statements and 20 unfavorable statements. The results of this study were analyzed using the Wilcoxon Sign Rank Test analysis, which yielded a Zcount of -2.160 with Asymp.Sig. (2-tailed) of 0.031, exemplifying a smaller value than the significance level (p< 0.05). The outcome indicates that the mentoring technique contributes positively to the improvement of self-efficacy of visually-impaired 7th to 9th-grade students of SLB A Yaat Klaten for the academic year 2018/2019.
The Concept of “Martabat Tujuh” Al-Burhanpuri (Study of the Creation of the Universe in the Perspective of Philosophical Sufism)
Authors: Rahman Fadli , Dakhoir Ahmad
Published: August 2021

When discussing the creation of the universe, the discussion will never be separated from the three objects of philosophical study, namely God as the creator, man and the universe as the created object, and at the same time being the object undergoing the process of creation. God, humans and the universe, are three objects that are always interesting to discuss. The manifestation of the existence of the three becomes a perennial study. For philosophers, these three problems become “fertile” areas of thought in the framework of developing true knowledge (correct knowledge) about these three problems. In the realm of Islamic thought, these three objects have always received major attention among Muslim philosophers, including the Sufis. Even in the context of Sufism (Sufism), these three objects become eternal discussions, especially at the level of Sufism which has philosophical nuances, or commonly known as “Falsafi Sufism”. At this level, the concept of “Martabat Tujuh”, a concept that talks about the creation of al-Buhanpuri’s version of the universe, is tried to be presented.
Why Am I a Muslim? Investigating the Truth of Faith Based on Ghazālī's al-Munqidh Min Al-Ḍalāl
Authors: Sajedi Akbar , Nemati Ali , Dargahzadeh Mohammad
Published: August 2021

It should be acknowledged that the man's beliefs are often based on their prejudices. Probably, some people have not even asked themselves "which religion do I believe in? and why?, let alone attempt to find answers to them. However, there are some who delve into these questions and strive to find convincing answers. Ghazālī was one of the thinkers who asked such questions when he was a teenager, and suffered from the resulting skepticism for a while. In Al-Munqidh Min Al-Ḍalāl, Ghazālī reports how he came across these questions and how he overcame the crisis of the skepticism. He criticizes those saying: "I am Muslim because I was born in a Muslim family", and presents a basis for the true faith, which is based on resorting to mysticism and abandoning the philosophical reasoning. Ghazālī does not view the true faith as the result of the combination of the major and minor premises, rather considers it merely as the Divine Illumination and providence. Using analytical-logical method, the present study examined the basis presented by Ghazālī and concluded that considering the Illumination as the basis of faith, and abandoning the philosophical reasoning may lead to some consequences which cannot be ignored. For example, in explaining the faith, by abandoning the philosophical reasoning, one cannot distinguish between the true faith and the false faith originating from the satanic temptations.
A Critique of Freud’s Theory Regarding Man’s Personality Structure from the Quran Perspective
Authors: Muhammad-Jafari Rasoul , Azimi Mohsen , Zamani Sadegh
Published: August 2021

Throughout the history of man, the Almighty assigned prophets to lead human beings. Along the same lines, the Almighty assigned the last prophet and provided him with the last divine book to offer to the people and lead them through the most complete religion. Hence this religion and its book would be a criterion for evaluating man’s thoughts. Freud was among one of the theoreticians who had an influential effect in human societies. He had a numerous theories regarding man, one of which was the description of human personality with the three concepts of id, ego, and super-ego. which opposes and is in contradiction with the teachings of the Quran. Hence, this study is after critically analyzing the structure of man’s personality from the Quran perspective. The findings of the study showed: (1) Freud seems to exclusively believe in one sole physical dimension for a man and no other dimensions while based on the Quran perspective and teachings, man is composed of the two dimensions of body and soul; (2) based on the Quran perspective, man is continually under the exposure of the two pulling and pushing forces of Havaye Nafs [Fads or wishes] and wisdom; (3) from the Quran standpoint, the personality of an individual is composed of three levels or layers: Nafs Ammarah; Nafs Lavvamah; and Nafs Motmaennah; and (4) there is reference to and confirmation of the hidden angles of human psych or mind in the holy Koran; yet, there is no reference to any hidden file for the repressed wishes.
The Experiential Marketing Forming Factors of Customers of the Traditional Concept Restaurants in Sleman Regency Special Region of Yogyakarta, Indonesia
Authors: Kartika Lucia Nurbani , Andalas Purwani Retno
Published: August 2021

The research objective was to identify and explain the forming factors of Experiental Marketing. This study used Experiential Marketing variables which were divided into Sense, Feel, Think, Act, and Relate. The research respondents were the customers of traditional concept restaurants in Sleman Regency, Special Region of Yogyakarta. The sampling technique used purposive random sampling method with data collection method by using a questionnaire that was distributed to 261 respondents. The research data were processed by using the Factor Analysis method. Then, exploratory factor analysis (EFA) was used because the formed factors were not determined in advance. Based on the factor analysis results, it could be concluded that there are four factors that influence and shape experiential marketing, namely the factors of Empathy, Atmosphere, Responsiveness, and Product Quality.
History of Islamic Education in Central Lombok (Historiography Study of Growth and Development NU Islamic Boarding School in Central Lombok)
Authors: Rahman Fathur , Taufik M. , Fadli Adi
Published: August 2021

Nahdlatul Ulama is one of the largest mass organizations in Indonesia and is an organization to be reckoned with in Central Lombok. The existence of NU from the start has become one of the important platforms whose existence is still not widely known by the public in spreading and spreading Islam in Central Lombok through various means such as education, preaching and social activities through Islamic boarding schools. This dissertation intends to answer the history of Islamic education in Central Lombok by discussing more specifically and in detail the Growth and Development Historiography of the NU Islamic Boarding School in Central Lombok. This study aims to obtain data on the entry and establishment of NU in Central Lombok, the dynamics of the Central Lombok NU education system and the relevance of education in Central Lombok NU with today's education. This dissertation uses qualitative research methods with field research. The data obtained were analyzed by means of qualitative data analysis, starting from data preparation, data classification, new data processing, interpretation and conclusion. Data mining was carried out by means of documentation, observation, and interviews. The research process was carried out intensively for more than one year in 11 NU Islamic boarding schools in Central Lombok, using a purposive sampling technique. This dissertation describes the history of the establishment of Central Lombok NU which was founded in 1953 and its figures include TGH Faisal, Lalu Ofoh, and L. Burhan and was assisted by several other administrators. As well as knowing the existing education system in the Central Lombok NU Institute so far has similarities in the form of components of the education system such as: learning objectives, about teacher conditions, number of students, learning methods, the curriculum used and the process and evaluation method. The learning carried out by the Educational Institution under the management of the NU Lombok Tengah boarding school is still very relevant to today's education, this is done by increasing human resources through various education and training and by improving supporting facilities such as building improvements, procurement of laboratories and other facilities.
The Effect of Leadership and Incentives on Work Motivation and Organizational Commitments (Study on Teachers of Islamic Boarding School in West Lombok)
Authors: Wahyudi Heri , Surati Surati , Suparman Lalu
Published: August 2021

The objectives of this study were (1) to analyze the significance of the influence of leadership on the organizational commitment of teachers at Islamic boarding schools in West Lombok. (2) To analyze the significance of the effect of incentives on organizational commitment. (3) To analyze the significance of the influence of leadership on work motivation. (4) To analyze the significance of the effect of incentives on teacher work motivation. (5) To analyze the significance of the influence of Work Motivation on Organizational Commitment. This type of research is associative quantitative research. The data collection method used by researchers is the census method. Respondents in this study were teachers as many as 83 peoples at Ishlahuddiny and Asshohwah Al Islamiah Islamic Boarding School. The data collected by questionnaire. The statistical test used SEM-PLS. The results showed that (1) Leadership has a positive and significant effect on Organizational Commitment. (2) Incentives have a positive and significant effect on Organizational Commitment. (3) Leadership has a positive and significant effect on Work Motivation. (4) Incentives have a positive and significant effect on Work Motivation.
Representation of Islamic Ecotheology in the Novel “Si Anak Kuat”, Tere Liye
Authors: Masyhuda Hilmy Mahya , Suwandi Sarwiji , Anindyarini Atikah
Published: August 2021

Ecological preservation needs to be done based on natural disparities. Islam teaches that the preservation of nature is also a commandment of Allah which is written in the Al-Qur'an. Literature is one of the good medium in reporting the importance of preserving nature. This study aims to represent the ecotheology of Islam in Tere Liye's novel “Si Anak Kuat”. The method used in this study is descriptive qualitative. Sources of data in this study are documents, namely “Si Anak Kuat” novel by Tere Liye. The technique to collect the data in this study is content analysis. Technique validity of data in this study using triangulation theory. Data analysis techniques using interactive data analysis techniques. The results showed that there are aspects that represent the ecotheology of Islam in Tere Liye's “Si Anak Kuat” novel. The aspects are 1) Tawhid, 2) Khilafah, 3) Amanah, 4) Fairness, and 5) Istislah. Studying Islamic ecotheology is the same as exploring environmental preservation in terms of Islamic teachings.
Scientific Evidences of the "Prostration Effect" on the Forehead of Some Prayer
Authors: Sharifi Mohammad , Hosseinzadeh Colagar Abasalt , Yazdanshenas Homayoon , Gorji Maryam , Hosseini Karnami Sayed Hossein
Published: August 2021

Prostration, putting forehead on the ground or clay-tablet, has many medical benefits. But some reports showed on the forehead of a few prayers it causes prostration effect/PE or clay-tablet effect/CTE, as a skin-callosity, on his/her forehead. This effect, which in Persian language is named Mohr-e-Pishani, has always been a curious question for researchers. Observation of the PE raises many questions in mind, which is not limited to the present time. For example; in old books 'Ali Ibn Al Husayn, Zainul Abedeen (PBUH), the fourth Imam of the Shia, has been nicknamed "Zol-Seqqnat" for having the CTE on his forehead which in the Arabic language means “the owner of skin-callosity”. The main purpose of this study was to uncover the scientific evidence of the PE on the forehead of some prayers. The results showed that several factors would result the development of PE, including physiological factors such as skin structure and its keratin content; allergens of the ground and soil as an external factor including chemical elements, acidity, macromolecules, and microorganisms. Physical factors, such as the way and duration of prostration, head weight concentration on the ground, soil or clay-tablet are also effective. These findings can answer some of the questions, curiosities, and possible doubts related to the phenomenon of PE or CTE on the forehead as a phenotype for other researches.
Environmentally Friendly Electric Energy Development Model
Authors: Hermawan Ahmad , Hakim Abdul , Marjono Marjono , Semedi Bambang
Published: August 2021

The increased production of electrical energy will lead to an increase on the use of fossil fuels which ultimately raise the Greenhouse Gas (GHG) emissions. The use of fossil fuels (non-renewable fuels) for large-scaled generation of electrical energy will certainly cause problems considering oil and coal reserves as the main source for PLTU will shrink and run out over time. In addition, several environmental problems need to be considered and studied regarding this condition. Thus, it is very important to efficiently use electrical energy according to Presidential Instruction No. 6 of 2014 concerning energy development which focused on sub-sectors electricity development and minimization of fossil energy use as well as development of new, renewable, and converted energies. Based on this, a system which can support energy saving is needed. A system used for regulating energy needs is called the Energy Management System (EMS). The study was conducted in the Malang State Polytechnic Campus which is located on Jalan Soekarno Hatta no. 9, Jatimulyo, Lowokwaru Sub-district, Malang City. The sample used in this study consists of 230 people, including 150 students, 30 lecturers and 50 academics. This study is purposed to examine the correlation of the four variables to the energy management system and the use of environmentally friendly energy. Thus, the most appropriate model to accommodate this requirement is Structural Equation Modeling (SEM). The results of SEM analysis showed that the model of an environmentally friendly electric energy management is said to be feasible to be developed, thus it can be collectively adapted in all aspects for creating a green campus.
Development of Local History Textbook of Tulang Bawang to Improve Historical Thinking Skills in Eleventh Grade Students Majoring in Social Science at SMA Negeri 1 Dente Teladas
Authors: Wahyuni Ike , Pargito Pargito , Sinaga Risma Margaretha
Published: August 2021

This study developed a textbook for the Local History of Tulang Bawang to improve the historical thinking skills of eleventh-grade social science students. This study is development research employing the ADDIE model as its development design with the following stages: (1) Analysis, (2) Design, (3) Development, (4) Implementation, and (5) Evaluation. The trial subjects consisted of expert trials consisting of material experts, media experts, and small group trials involving 6 students. Then, field trials were carried out in the eleven-social-one class as a treatment class. The data were collected through questionnaires, observation, and documentation. The obtained data were analyzed using qualitative and quantitative analysis. Product effectiveness was tested by comparing the historical thinking skills of students in eleven science one class as the experimental class and eleven science two as the control class. The results of the study found that 1) the local history textbook of Tulang Bawang was developed using the ADDIE model steps. 2) The local history textbook of Tulang Bawang was able to improve historical thinking skills. After using development products, there was a difference in learning outcomes of 0.50 with moderate criteria indicating that the development product is effective in improving students’ historical thinking skills. 3) The learning activities of eleven social one class which used the Tulang Bawang local history textbook were more effective than the eleven social two class which did not use the Tulang Bawang local history textbook.
The Effect of Financial Performance on Performance Accountability of Regency/City Governments in Indonesia
Authors: Jannah Miftahul , Mahmud Muhtar , Winarna Jaka , Sutaryo Sutaryo
Published: August 2021

This research is intended to provide empirical evidence of the influence of financial performance on the accountability of city government performance in Indonesia. The sample in this study is 1226 district / city governments in indonesia 2012-2014. The data is formed into a combined panel data between time series data and cross section data that is processed using multiple regression model. Financial factors are proxied by regional financial independence, activity ratios, ratios of development function, intergovernmental income, and fiscal capacity. The results of this study indicate the ratio of regional financial independence, health ratio, fiscal capacity positively affect the performance accountability of local governments in Indonesia. While the ratio of development activities and intergovernmental income does not apply to the performance accountability of local governments in Indonesia.
The Development of Statistic Instructional Materials for Integrated Student about Electronic Publishing Based Statistical Literacy
Authors: Ratnawati Oktaviana Ainun , Eko Siswono Tatag Yuli , Wijayanti Pradnyo
Published: August 2021

Good instructional materials are arranged systematically and they enable students to learn independently, up to date, easily digestible and designed in accordance with the applicable curriculum. This research aimed to determine the process and results of the development of integrated statistical instructional materials EPUB-based statistical literacy properly (valid, practical, and effective) and to determine whether there were significant differences between the pretest-posttest results. The type of research used was Research and Development (R&D) with the ADDIE type development model. The subjects in this research were 53 students of the mathematics education study program at Universitas Palangkaraya (UPR) and 41 students of the PGSD study program at Universitas Mushammadiyah Palangkaraya (UMPR). Data analysis used T-test and N-Gain test. The research results obtained were as follows: (1) The instructional materials developed contained statistical literacy and multimedia based, namely EPUB (2) The average validity obtained from the validator's assessment was 89.42% very valid of 89.42% (3) The average percentage of student responses to EPUB-based statistical literacy integrated instructional materials was 89.82%. Overall, instructional materials were in the very practical category. (4) student learning completeness reached 80.76%, there were 30 of 31 UPR students completed and student learning completeness reached 78, 80%, there were 22 UMPR students completed and it can be concluded that the use of EPUB was effective. (5) Furthermore, a significant difference can be seen from the UPR average of the experiment class posttest was 84.23 while the posttest control class was 61.23. It means that the post-test results of the experiment class were higher than the post-test results of the control class with a difference of 23 and the result of the N-gain score for the experiment class is 56.3% while the control class is only 4.24%. Meanwhile, a significant difference can also be seen from the average UMPR of the posttest experiment class was 78.14 while the posttest control class was 63.00. It means that the post-test results of the experiment class were higher than the post-test results of the control class with a difference of 15.14 and the results of the N-gain score for the experiment class are 56% while the control class was only 10%.
Due to the Financing Company’s Capital as a Fidusian Recipient of Fidusian Security Objectives
Authors: Wiryadharma Erick , Saleh Moh.
Published: August 2021

The type of research used in this research is normative legal research. The transfer of ownership rights to the Fiduciary Collateral Objects is handed over in a constitutum possessorium, which means that the trustworthiness of the guaranteed property (the debtor's property) is transferred to the creditor, with physical control over the goods remaining with the debtor. Where it’s agreed that the owner of the object will surrender his/her right over the object to the Fiduciary. But with a promise that the owner of the object may still use it and then hold onto the object for the Fiduciary. So the status, the person who was originally the owner, is now a borrower. In this incident, there was no real surrender, but only based on an agreement.
The Comparison of the Paris and Istanbul Manuscripts of Mirajname
Authors: Turdiev Jakhongir
Published: August 2021

Muhammad (peace and blessings of Allah be upon him) was sent on a journey from al-Haram mosque in Mecca to al-Aqsa mosque in Jerusalem, this night journey is called al-Israh. During this journey, the Messenger (peace and blessings of Allah be upon him) ascended to heaven. The Ascension of the Prophet (p.b.u.h) is called Miraj. The night of the Ascension or al-Isra wal Miraj is a great honor bestowed by the Almighty upon the Prophet Muhammad (p.b.u.h) alone, during Miraj, the Prophet (p.b.u.h) witnessed miracles beyond the comprehension of men, and was shown rewards corresponding to the deeds of men... Prophet Muhammad saw the Inhabited House or the heavenly Al-Ka'ba, as well as Paradise, Hell and Arsh and many more. Miraj is one of the most famous events in the history of Islam and one of the most important themes in classical Oriental literature. The works devoted to this event are called Mirajnamae. The Mirajnames generally refer to the same theme, but differ from each other in detail and wording. This article is dedicated to the comparison of the Paris and Istanbul manuscripts of the Turkic Mirajnamae. The article analyzes the differences in the Uyghur and Arabic manuscripts from a textual point of view.
The Principle of Synderesis in Interpreting Legislation
Authors: Michael Tomy , Siregar Erwin , Siregar Ryan Gabriel , Lastika Yasa I Wayan , Wirangga Kusuma I Made
Published: August 2021

In this study, the method of legal interpretation plays an important role in finding answers to research questions. In the study of statutory regulations, understanding a statutory regulation requires a separate understanding technique. Does the understanding technique itself use reading or interpreting techniques, but all of which must produce the common good. This common good is often called the bonum commune. In the study of legal philosophy, legal justice is the highest goal of law. In the concept of the welfare state, bonum commune is an entity related to the teleology of the felling of being well. Bonum commune doesn’t mean that we define a standard principle that must be enforced and apply to everyone. Bonum commune is related to human awareness as part of a community that needs each other and leads to a good state of society. The principle of synderesis when used to interpret the entire Regent Decree Number 20 of 1997, the legal solution was found, namely Batu Tiga Village existed before the Regent’s Decree Number 20 of 1997 because the statutory regulations that were ius constitutum originated from the prevailing customs in the community.
Legal Protection for Village Communities Against Land Rights in the Construction of a National Strategy Project Through a Complete Systematic Land Registration System (Study of Pasuruan District Land Registration)
Authors: Kumalasari Ratna Biraeng
Published: August 2021

In this study using normative legal research. Policies related to land are required to guarantee legal certainty and certainty of land ownership rights by every person (individual) or by legal entities. So the community needs to register land in order to obtain a certificate of land rights which serves as a strong means of proof of ownership of land rights by someone. Meanwhile, Article 19 paragraph (1) of the Basic Agrarian Law states that to ensure legal certainty by the Government, land registration is held throughout the territory of the Republic of Indonesia. This is done so that land owners can obtain legal certainty for the land they have owned, and it’s intended that rights holders obtain valid evidence in the form of certificates as a strong means of proof as holders of rights to the land they own. Starting from the description above, the researcher can provide several aspects of the study, including: First, the Complete Systematic Land Registration (PTSL) target is so large that it’s not an easy job for the Pasuruan Regency land office, which has 29 State Civil Servants, assisted by 63 non-government employees, due to the limited number of existing staff, the implementation of the Complete Systematic Land Registration (PTSL) land office in Pasuruan Regency involves; 1. The private sector as a third party helping 20,200 fields for measurement and mapping activities, 2. Community participation in assissting Complete Systematic Land Registration (PTSL) in village locations for 10,100 respectively, and 29,700 fields carried out and carried out by the Pasuruan Regency Land Office ASN.
Social Entrepreneurship Canvas Business Model to Improve Family Welfare: A Case Study of the Culinary Business of “Special Fried Quail” at Purwareja Klampok Banjarnegara
Authors: Lumbantoruan Barmen Brevis , Pangeran Perminas
Published: August 2021

This study aimed to develop an entrepreneurial canvas model through evaluating the nine components of the canvas business model to support the empowerment and welfare of culinary business’ members of the Special Fried Quail in Purwareja Klampok District, Banjarnegara and to develop a social entrepreneurship business model. The research strategy was a quantitative case study with an evaluation method. Data collection techniques were carried out using a questionnaire. The analysis model used a Logic Model framework (input, activities, output, and outcome) and a canvas business model. The results of the evaluation research showed that the business model’s orientation was more incline towards commercial business. As its implication, the Special Fried Quail culinary business model’s development in the future would be more directed to the social entrepreneurship business model in order to improve family welfare.
Management of Character Education at Integrated Islamic Elementary School, Gowa and Al-Biruni Mandiri Makassar Integrated Islamic Elementary School: A Multi-Case Study
Authors: Hasan Salim , Rahman Abdul , Bunyamin Andi , Hasibuddin Hasibuddin
Published: August 2021

This study aims to determine, study and analyze character education management and its effectiveness at SDIT Al-Fityan School Gowa and SDIT Al-Biruni Mandiri Makassar. This research is a qualitative research with a phenomenological approach. The method of collecting data is through interviews with school principals, vice principals for curriculum affairs, students, homerooms and teachers. Other data sources are through observation and documentation. The data obtained were analyzed by data reduction steps, data presentation and conclusion drawing. The results of this study indicate that character education planning begins with establishing the school's vision, mission, goals and programs, as well as determining character values, designing a curriculum that integrates character values into an integrated syllabus and lesson plans based on Islamic education. The organization of character education is carried out by the principal through coordination between elements, division of tasks based on SOPs, controlling and evaluating. implementation. Implementation of character education through (1) integrating character values into Islamic values-based learning, (2) through apperception activities or morning briefings, (3) mentoring activities or Islamic Personal Development, (4) Al-Qur'an mentoring, outing class and outbound. Character education is also carried out through extracurricular activities, habituation of worship and Islamic etiquette, modeling and school culture. Supervision of character education from the principal, and homeroom supervision of students through mutaba'ah/scoring boards. The implementation of character education has formed students who are able to be religious, able to apply Islamic etiquette, very good in tolerance, speak politely, independently, help, socially care, honest, disciplined, confident, cooperative and responsible.
Types and Functions of Taxes in a Market Economy
Authors: Yuldasheva Isabella Rustambekovna , Artikov Nematulla Abdusalamovich
Published: August 2021

The purpose of this article is to explain the role and importance of taxes in a market economy based on economic analysis. There are also economic considerations about the types of taxes, and the importance of the functions of taxes in today’s market economy has been scientifically demonstrated. The role of taxes and types of taxes in the regulation of the economy, the results of economic measures taken to introduce taxes in the economic growth of the country are presented in statistics. Through an in-depth analysis of the role of tax functions in the economy, we can identify them as a key factor in ensuring the country's budget. The large-scale work carried out in our country to ensure greater transparency of tax policy determines the relevance of this sector for today's market economy.
Individual Differences in Second Language Learning
Authors: Turakulova Hilola Sayfiddinovna , Marupova Dilfuza Davronovna
Published: August 2021

This article is directed to identify learners needs and organize the further procedure of language teaching and learning. To this extend, teachers should identify the learner’s personality, character, and learning styles, they may comprehensively organize lesson procedures and use various methods in an appropriate manner and finally, they will be able to receive high outcomes in the field of language teaching.
The Role of Parental Love in the Mental Health of Children from the Perspective of the Qur’an and Hadith
Authors: Salehizadeh Mohammad Ismail , Abbasi Narges
Published: August 2021

Parental affection for children is a natural and necessary thing and its role in the mental health of the child is not less than meeting basic needs. Considering the importance of this issue in religious teachings and its great impact from different dimensions on the mental health of children, the purpose of this study is to explain the role of parental love in children's mental health through a descriptive-analytical method and using the Qur’anic verses and hadiths from reliable sources. Through this research, it has been proven that the parental love from the perspective of the Qur’an and Hadith causes motivation, the promotion of moral virtues, socialization, hope, etc. in children and is very effective in their mental health, providing healthy families and consequently leading to a healthy society.
Effect of Postoperative Specific Immunotherapy Combined with Nasal Irrigation on Chronic Rhinosinusitis with Allergic Rhinitis
Authors: Li Jia , Kang Houyong , Hong Suling , Shen Yang
Published: August 2021

Patients with chronic rhinosinusitis (CRS) and allergic rhinitis (AR) (CRSwAR) have a more severe condition with a higher rate of recurrence after endoscopic sinus surgery (ESS). This study aimed to explore the effect of specific subcutaneous immunotherapy (SCIT) and nasal irrigation on CRSwAR after ESS.
Sixty-four patients who were diagnosed as CRSwAR and received ESS were enrolled and divided into groups A, B, and C to receive different postoperative treatment strategies (conventional medication, medication with nasal irrigation, and medication with nasal irrigation and SCIT), and their prognosis was evaluated by scoring, electron microscopy, and inflammatory factors.
One year after ESS, the recurrence rate of group C was significantly reduced; and the scoring from baseline was significantly different among the three groups, which of group C were the best. The epithelium arrangement, cilia morphology, and inflammation of nasal mucosa in each group were better than those in the preoperative state; and those in group C were the best. After one year, the expression levels of eosinophil cationic protein (ECP), interleukin (IL)-8, and IL-17 in group B were lower than those of group A; and the expression levels of ECP, IL-8, IL-25, IL-33, IL-17 in group C were lower than those in group A.
SCIT combined with nasal irrigation can improve the patients' symptoms and quality of life, promote the epithelialization of the mucosa in the surgical cavity, regulate the local immune response of the nasal cavity; thus improve the prognosis of patients with ESS after 1 year.
Evaluation of TAK-242 (Resatorvid) Effects on Inflammatory Status of Fibroblast-like Synoviocytes in Rheumatoid Arthritis and Trauma Patients
Authors: Karami Jafar , Farhadi Elham , Delbandi Ali-Akbar , Shekarabi Mehdi , Naghi Tahmasebi Mohammad , Sharafat Vaziri Arash , Akhtari Maryam , Mousavi Mohammad Javad , Jamshidi Ahmadreza , Mahmoudi Mahdi
Published: August 2021

Fibroblast-like synoviocytes (FLSs) produce lots of inflammatory molecules that trigger immune responses and intensification the inflammation and thereby play important roles in Rheumatoid Arthritis )RA( pathogenesis. Due to the important roles of toll-like receptor 4 (TLR4) in cytokine production and inflammation, we aimed to evaluate the effects of TAK-242 (Resatorvid) on interleukin (IL)1-β, IL-6, TNF-α, and TLR4 expression and two important proteins of nuclear factor-κB (NF-κB) signaling pathway (Ikβα and pIkβα) in RA and trauma FLSs.
FLSs were isolated from synovial tissues of trauma (n=10) and RA (n=10) patients and cultured in Dulbecco's Modified Eagle Medium (DMEM). 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) was performed to evaluate the cytotoxicity effects of TAK-242 on the RA FLSs. Real-time PCR was performed to measure the expression level of IL1-β, IL-6, TNF-α, and TLR4 genes in Lipopolysaccharide (LPS) and TAK-242 treated FLSs. Furthermore, the treated FLSs were evaluated for protein levels of Ikβα and pIkβα by western blot.
The baseline expression of IL1-β, IL-6, TNF-α, and TLR4 showed no significant differences between healthy and RA FLSs. LPS stimulated FLSs significantly increased mRNA levels of IL-1β, IL-6, TNF-α, and TLR4 genes in both the healthy and RA FLSs compared with that of their control groups, and pretreatment with TAK-242 reversed the effect. Furthermore, LPS-stimulated FLSs significantly increased the level of pIkβα in both the healthy and RA FLSs compared with that of their control groups, and pretreatment with TAK-242 reversed the effect.
We provide the data that TAK-242 through inhibiting the NF-κB signaling pathway may modulate TLR4-mediated inflammatory responses and could be considered as a potential therapeutic agent for RA patients.
Immunogenic Potency of a Chimeric Protein Comprising InvH and IpaD against Salmonella and Shigella spp
Authors: Emami Mahmoudabadi Fahimeh Sadat , Vakili Atina , Nazarian Shahram , Amani Jafar , Mousavi Gargari Seyed Latif
Published: August 2021

Shigella and Salmonella cause serious problems in many subjects, including young children and the elderly, especially in developing countries. Chimeric proteins carrying immunogens increase immune response. In-silico tools are applied to design vaccine candidates. Invasion plasmid antigens D (ipaD) gene is one of the Shigella virulence factors. The N-terminal region of the IpaD plays a significant role in invading the host cell. Invasion protein H (invH) gene plays important role in bacterial adherence and entry into epithelial cells. A recombinant chimeric construct, containing IpaD and InvH was designed and used as a vaccine candidate against Shigella and Salmonella enteritidis.
After bioinformatics assessments, the construct was designed, synthesized, and expressed in E.coli. Chimeric protein, IpaD, and InvH were purified with Ni-NTA chromatography. Purified proteins were confirmed with western blotting and then were injected into separate mice groups. The antibody titer was estimated with an enzyme-linked immunosorbent assay (ELISA). Mice were challenged with 10, 100, and 1000 LD50 of Salmonella, and the sereny test was performed for Shigella.
The Codon adaptation index of the chimeric gene was increased to 0.84. Validation results showed that 97.9% of residues lie in the favored or additional allowed region of the Ramachandran plot. A significant antibody rise was observed in all test groups. The immunized mice with chimer and InvH could tolerate 100 LD50 of Salmonella. In the sereny test, the application of bacteria treated with immunized mice sera of both antigens showed no infection in Guinea pigs' eyes.
The recombinant protein could protect animal models against Salmonella and Shigella and therefore can be considered as a suitable vaccine candidate against these two pathogens.
Safety of Methotrexate in Chronic Urticaria Unresponsive to Omalizumab
Authors: Unsel Mehmet
Published: August 2021

Omalizumab (humanized anti-immunoglobulin IgE) is currently the first choice of treatment for chronic urticaria refractory to high-dose second-generation antihistamines (sgAH). Despite its high safety profile, response to omalizumab is insufficient in one-third of patients. Some studies have suggested that methotrexate is effective in antihistamine-refractory chronic urticaria, but there are no studies on its efficacy and safety in patients unresponsive to omalizumab. This retrospective study aimed to investigate the clinical effectiveness and adverse effects of methotrexate in patients with chronic urticaria unresponsive to omalizumab+high-dose sgAH.
The patients were evaluated in terms of age at disease onset, duration of the urticaria episode before methotrexate therapy, treatment before methotrexate therapy, final treatment, treatment responses, 7-day urticaria activity score (UAS7) before and after treatment, and total IgE levels. Methotrexate was administered subcutaneously at a dose of 15 mg once weekly as monotherapy or in combination with other drugs to 10 chronic urticaria patients with a history of nonresponse to omalizumab+high-dose sgAH.
The mean age of the patients was 44.6±11.5 (31-65) years, and 9 (90%) of the patients were female. The mean duration of methotrexate therapy was 5.1±2.4 months (1.5-9 months). Complete response or well-controlled response was observed in 70% of the patients and partial response was observed in 1 patient (10%).
Methotrexate was well tolerated by 80% of the patients. Methotrexate seems to be a useful treatment option both as monotherapy or combined therapy in patients resistant to omalizumab+sgAH.
CP-Tania 5, white maize variety horse’s tooth (Claviceps gigantea) resistant for Mexican highlands
Authors: De León-García de Alba Carlos , Solano-Báez Alma Rosa , Márquez-Licona Guillermo , Sánchez-Pale Jesús Ricardo
Published: August 2021

En el Colegio de Postgraduados se desarrolló la variedad sintética de maíz de grano blanco con buenas características agronómicas y resistencia al diente de caballo para zonas de transición y altiplano de México. C. gigantea ha sido reportado solo en México, sin embargo, se ha distribuido en zonas productoras de maíz en el altiplano y zonas de transición con clima fresco y alta humedad. La variedad se generó recombinando 10 líneas S1 generadas a partir de una población base de maíz con endospermo blanco y amplia base genética. La población se mejoró siguiendo un programa de selección recurrente en líneas S1. Las líneas obtenidas se seleccionaron después de inocular con macroconidios del hongo y las mejores se recombinaron para generar variedades sintéticas, entre las cuales la variedad CP-Tania 5 fue sobresaliente. Esta variedad sintética ofrece rendimiento de grano que compite con el de híbridos comerciales, la semilla es de menor costo, puede sembrarse por varios ciclos en condiciones limitantes y puede distribuirse entre agricultores.
Participación comunitaria en el mecanismo Transferencias Directas Condicionadas del Programa Bosques
Authors: Palacios Grace
Published: August 2021

Chirikyacu, Chunchiwi y Chirik Sacha, ubicadas en la región San Martín (Perú), son comunidades nativas afiliadas al Programa Bosques. En las tres se aprobó la implementación del mecanismo Transferencias Directas Condicionadas (TDC) como instrumento financiero para la conservación de su bosque primario. Esta investigación caracteriza la participación de los beneficiarios a partir del tipo de involucramiento y cantidad de participantes en la ejecución del TDC, identificando factores que facilitan o limitan la participación del grupo beneficiario minoritario.Las minorías, como en cualquier sociedad, acceden a menores oportunidades. En las tres comunidades se encontraron grupos minoritarios más numerosos (e.g.: mujeres) que otros (e.g.: mono-lingües), también se encontraron normas de género aceptadas que limitan a los grupos minoritarios de experimentar desenvolvimiento y aprendizaje. Con los aportes del 86% de familias beneficiarias, se identificó un sistema no complementario de género en la mayoría de las actividades del programa, que además es predominante en el grupo más favorecido de la comunidad.Se concluye que el grupo minoritario principal puede aumentar la cantidad de participantes a partir de las oportunidades que permita la complementariedad de género que rige en cada comunidad (factor interno) y del enfoque de género que incorpore el programa Bosques (factor externo).
El discurso en los proyectos culturales de la música latinoamericana: de la nueva canción a la canción social en Colombia
Authors: Katz-Rosene Joshua , Castelblanco Daniel
Published: August 2021

En este artículo rastreo los discursos que circundan la denominada «música latinoamericana», una categoría musical bastante amplia que reúne diversos géneros folclóricos latinoamericanos, especialmente andinos, y que se encuentra inscrita en «proyectos culturales» sucesivos e interrelacionados. Examino los significados extramusicales que movimientos contestatarios como la nueva canción, en el Cono Sur, y la red transnacional de la nueva canción latinoamericana atribuyeron a este estilo musical, para luego enfocarme en el desarrollo que tuvo la música latinoamericana en Colombia. A mediados de la década de 1970, los primeros intérpretes colombianos de música latinoamericana adoptaron numerosas facetas del discurso relacionado con la nueva canción latinoamericana, incluyendo sus modelos musicales. Sin embargo, no tardaron en refinar sus argumentos acerca del significado del estilo, su peculiaridad frente a otros géneros musicales y su simbolismo político, con el propósito de adaptarlos a los cambiantes contextos culturales de las ciudades colombianas del interior. Sostengo que el «trabajo» discursivo que asumieron estos proyectos culturales ha conseguido que, en Colombia, la música latinoamericana siga siendo equiparada a tendencias políticas contestatarias y que, por tanto, se mantenga estrechamente vinculada a la «canción social», la categoría vigente para la música socialmente comprometida.
Determining Serum Haptoglobin and Proinflammatory Cytokines Concentration in the Calves Clinically Diagnosed with Pneumonitis, Pneumoenteritis and Enteritis
Authors: Kabu M. , Uyarlar C.
Published: August 2021

Background: This study aims to determine the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α) in cases of Pneumonia, Pneumoenteritis and Enteritis. Methods: 60 calves were subjected to the study and they were divided into four groups. The study group consisted of the claves diagnosed with clinical pneumonia (Group P; n=15), pneumoenteritis (Group PE; n=15) and enteritis (Group E; n=15) while the control group included the healthy calves (Group C; n=15). The measurements of the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α), Total protein (TP) and Albumin (ALB) were made by using commercial kits. Conclusion: In all infection groups (P, PE ve E), Haptoglobin concentration, serum cytokine (IL-1β, IL-6 and TNF-α) and Albumin values were found to have been higher than the control group (p≤0,005). However, there was no difference in total protein. In the light of these findings, it is suggested that routine controls for Haptoglobin and cytokine (IL-1β, IL-6 and TNF-α) concentrations would be rewarding to determine the severity of the infection, to choose the suitable treatment and to detect subclinical infections in veterinary medicine.
Optimization of Enzymatic Extraction of ACE Inhibitory Peptide from Rohu (Labeo rohita) Fish Waste using RSM
Authors: Kumar Vikas , Shakila R. Jeya , Muzaddadi A.U. , Jeyasekaran G. , Sukumar D. , Padmavathy P. , Kumar Yogesh
Published: August 2021

Background: Hypertension is one of the cardiovascular disease that kills people silently across the globe. It can be controlled, in one of the way, by ACE inhibitory peptide extracted from aquatic resources. Methods: Rohu (Labeo rohita) fish wastes were quantified for their anatomical yield; analyzed for their proximate composition and optimized the enzymatic extraction parameters for ACE inhibitory peptides. Response surface methodology with Box-Benhken Design (RSM-BBD) was used to optimize alcalase concentration (0.5-2% v/w), hydrolysis temperature (45-60°C), hydrolysis time (60-240 min.) and solid: liquid (S/L) ratio (0.2-1) to obtain rohu fish waste peptides. Results: More waste generated in smaller (49.4%) than medium and bigger (34.5%) fish. Quantum of edible flesh (59.06%) was followed by head (23.9%), trimmings (5.18%), scales (4.19%) and swim bladder (0.65%). However, protein content was highest in swim bladder (34.1%) followed by scales (22.9%), trimmings (18.7%) and head (17.1%). Alcalase concentration (1.08%, v/w), temperature (52.10°C), hydrolysis time (129.18 min) and S/L ratio (0.8:1) were found optimum for extraction ACE inhibitory peptide with DH, ACE inhibition and PY of 19.27%, 54.98% and 51.37% respectively. Results showed the potential of extracted ACE inhibitory peptide as ingredients in functional food.