bluuebunny/crossref_metadata_2025 huggingface dataset:
Bisphenol A Induces Agrp Gene Expression in Hypothalamic Neurons through a Mechanism Involving ATF3
Authors: Loganathan Neruja , McIlwraith Emma K. , Belsham Denise D.
Published: June 2020

Background: Bisphenol A (BPA) is a ubiquitous endocrine disrupting chemical and obesogen. Although limited evidence exists of the effects of BPA on hypothalamic agouti-related peptide (AgRP) levels, the mechanisms underlying these effects remain unknown. Given that AgRP is a potent orexigenic neuropeptide, determining the mechanism by which BPA increases AgRP is critical to preventing the progression to metabolic disease. Methods: Using quantitative reverse transcriptase polymerase chain reaction, we investigated the response of Agrp-expressing mouse hypothalamic cell lines to BPA treatment. The percentage of total BPA entering hypothalamic cells in culture was quantified using an enzyme-linked immunosorbent assay. In order to identify the mechanism underlying BPA-mediated changes in Agrp, siRNA knockdown of transcription factors, FOXO1, CHOP, ATF3, ATF4, ATF6, and small-molecule inhibitors of endoplasmic reticulum stress, JNK or MEK/ERK were used. Results: BPA increased mRNA levels of Agrp in six hypothalamic cell lines (mHypoA-59, mHypoE-41, mHypoA-2/12, mHypoE-46, mHypoE-44, and mHypoE-42). Interestingly, only 18% of the total BPA in the culture medium entered the cells after 24 h, suggesting that the exposure concentration is much lower than the treatment concentration. BPA increased pre-Agrp mRNA levels, indicating increased Agrp transcription. Knockdown of the transcription factor ATF3 prevented BPA-mediated increase in Agrp, pre-Agrp, and in part Npy mRNA levels. However, chemical chaperone, sodium phenylbutyrate, JNK inhibitor, SP600125, or the MEK/ERK inhibitor PD0352901 did not block BPA-induced Agrp upregulation. Conclusion: Overall, these results indicate that hypothalamic Agrp is susceptible to dysregulation by BPA and implicate ATF3 as a common mediator of the orexigenic effects of BPA in hypothalamic neurons.
THE IMPORTANCE OF TRAINING TECHNOLOGIES IN THE FORMATION OF INTERCULTURAL COMPETENCE OF FUTURE SOCIO-HUMANITARIAN PROFESSIONS
Authors: Rebukha L. Z. , Rambu Nicolae
Published: June 2020

The problem of formation of intercultural competence in future specialists of socio-humanitarian sphere in higher education institutions is actualized in the article. The review of modern scientific approaches to the definition of the term “intercultural competence” is made. Intercultural competence is attributed to the group of leading competences of both the personality and professional competences of the future specialist of socio-humanitarian professions. The content of intercultural competence with personal, informational and activity components is presented; its structural components including general cultural and cultural-specific knowledge, professionally-oriented skills and abilities, intercultural psychological perception, personal reflection and ways of subjective interaction have been identified and characterized. The levels and stages of personal growth of students towards the formation of a multicultural personality are revealed. The intercultural competence of the future specialist is presented as an integrative quality, which ensures his/her readiness for professional activity in the conditions of ethno-cultural diversity of the modern society. The importance of using cultural-directed socio-psychological training for the formation of intercultural competence in groups of students of other cultures, which consistently produces motivation and knowledge and enables their practical application in the students group in interaction with representatives of other cultures; contributes to the resolution of conflicts arising from ethnic diversity; generates positive-personal reflective processes to gain experience of professional interaction with representatives of other cultures; projects his/her own experience in the following situations of future professional activity, are described in the article. The criteria of forming (motivational, cognitive, activity, reflexive) professional intercultural competence of specialists in the process of using training technologies are described.
DISTANCE LEARNING OF FUTURE DOCTORS IN FOREIGN LANGUAGE: CHALLENGES OF TIME
Authors: Fedchyshyn N. O. , Yelahina N. I. , Permyakova O. H.
Published: June 2020

The article deals with the problem of the use of foreign (English, German) language distance learning for the training of future doctors. It has been analyzed the advantages and disadvantages of modern distance learning for students, teachers and higher educational institutions (oriented learning, personalization and differentiation of pedagogical activity). The main normative documents that regulate the development of distance learning in Ukraine are proposed. Great attention is paid to the problems and methods of distance learning, peculiarities of learning a foreign language by means of distance learning, some issues in the practice of teaching a foreign (English, German) language in the distance educational system for students of non-linguistic specialties on the basis of educational platform Moodle (types of activities offered by the platform, external resources useful for the use of distance learning in foreign languages). The concept of an adaptive approach to distance learning as a motivational factor in learning foreign languages ​​is characterized.
LATIN AS A COMPONENT OF FUTURE NURSERS’ PROFESSIONAL EDUCATION
Authors: Vorona І. І. , Kolodnytska O. D.
Published: June 2020

The article points out the specifics of future nurses’ terminological competence development by using Latin medical terms. Mastering Latin medical terminology is obligatory for intercultural communication particularly in the nurses’ professional activity. The course “Latin and the Basis of Medical Terminology” contributes to the future nurses’ development of linguistic and terminological culture during professional training.

Modern requirements include mastering the professional language (terminology) for specialists in different fields of knowledge.

Understanding between colleagues and the qualified treatment often depend on the ability to formulate correctly special information orally or in written form, and the ability to be able to communicate professionally with co-workers more fluently and more confidently. Knowledge of professional terminology helps to gain a deeper understanding of specialized literature and to develop professional erudition. Nowadays, it is necessary to use methods allowing to optimize the educational process due to the most effective use of allotted time for the nurses’ terminological competence development.

The nurses’ terminological competence is developed during the study of the course “Latin and the Basis of Medical Terminology”. It will help nurses master Professionally Oriented Study Programmes: Anatomy, Histology, Therapy, Clinical Courses, Chemistry, Pharmacology, Pharmacognosy, etc.
Por que é tão difícil inovar nas práticas de ensino? Um modelo de formação universitária centrado na saúde pedagógica
Authors: Aguiar Joana Guilares de
Published: June 2020

O ambiente de ensino universitário é dinâmico e complexo. Porém, as abordagens didáticas continuam sendo prevalentemente conservadoras, tradicionais e focadas na transmissão de conteúdo disciplinar. Apesar da necessidade de inovação didático-pedagógica, por que, na prática, ainda parece ser tão difícil inovar em nossas práticas de ensino? Este artigo tem o objetivo de explorar uma visão humanista para abordar o problema, focada na promoção da saúde pedagógica na universidade como forma de potencializar esforços individuais e institucionais para uma educação inovadora.
Ele e Ela
Authors: Barbosa Melissa Teixeira
Published: June 2020

“Ele e Ela” (Он и Она) foi publicado pela primeira vez pela revista “Mirskói Tólk” (Мирской толк), em 23 de Julho de 1882. Dois anos mais tarde,  em 1884 , foi publicado na coletânea “Contos de Melpômene” (Сказки Мельпомены) após sofrer algumas alterações. Tchékhov assinou essa obra utilizando um de seus pseudônimos, A. Tchekhonté, derivado de seu sobrenome. No presente conto acompanhamos o relacionamento conflituoso entre uma cantora famosa e seu marido em meio ao ritmo agitado dos banquetes e dos personagens da esfera teatral.
La fotografía rusa durante la NEP. Un campo experimental y revolucionario (1921-1928)
Authors: Finelli Renata Carla
Published: June 2020

La Nueva Política Económica (NEP) implementada por Vladímir Ilich Lenin en 1921, produjo nuevas preocupaciones dentro del campo artístico. Las opiniones de los soviets en cuanto a la NEP estuvieron divididas a favor y en contra de ésta. Para muchos de ellos, la NEP amenazaba su trabajo debido al fomento de la producción de las empresas privadas y la introducción de nuevas tecnologías; mientras que, para otros, significaba el punto de partida de la reanudación económica que permitiría la entrada de bienes de poco alcance hasta entonces. La importación de productos tecnológicos abrió un nuevo panorama artístico que estimuló y colocó a la fotografía en el centro de la escena. El presente trabajo se propone contar los distintos usos y formas de circulación que tuvo la fotografía durante los años revolucionarios de la NEP.
Monteiro Lobato e Samuel Marchak através de seus ilustradores
Authors: Mountian Daniela
Published: June 2020

Nos anos 1920, iniciou-se uma revolução global da arte do livro, momento em que começaram a atuar Samuel Marchak (1867-1964) e Monteiro Lobato (1862-1948), duas figuras-chave para o desenvolvimento da moderna literatura infantil de seus respectivos países: Marchak na Rússia, Lobato no Brasil. Além de escritores, ambos foram tradutores e importantes editores, reunindo ao redor de si artistas gráficos e pintores de escolas variadas. O artigo apresentará a trajetória de Marchak e Lobato através da análise de algumas capas infantojuvenis da década de 1920 produzidas para eles por Voltolino (1884-1926), Belmonte (1896-1947), K. Wiese (1877-1974), V. Lébedev (1891-1967), V. Konachévitch (1888-1963), M. Tsekhanóvski (1889-1965).
Púchkin e Machado, o ser negro, formas de ouvir o outro
Authors: Fuentes Susana
Published: June 2020

Este estudo pretende, em leituras de Púchkin e aproximações de Machado, analisar, em perspectiva comparada, o lugar de visibilidade da herança afrodescendente em Aleksander Púchkin (1799-1837) na literatura russa e Machado de Assis (1839- 1908) na literatura brasileira.  Perceber, entre margem e centro, a voz plural e inovadora do autor russo, seus caminhos até o outro. Em Puchkin, a viagem. Fronteiras possíveis. O olhar para si que se deixa atravessar pela diferença. Em Machado, seu olhar para as máscaras sociais e para a escravidão. Nesses autores, marcas em sua literatura que formam a sua casa e o seu tempo, em diálogo com a modernidade. Na abertura para o outro, leituras onde o que estava no lugar do cânone também se modifica, escurecendo o imaginário nos novos contextos.
Levels and Change in Galectin‐3 and Association With Cardiovascular Events: The ARIC Study
Authors: Aguilar David , Sun Caroline , Hoogeveen Ron C. , Nambi Vijay , Selvin Elizabeth , Matsushita Kunihiro , Saeed Anum , McEvoy John W. , Shah Amil M. , Solomon Scott D. , Boerwinkle Eric , Ballantyne Christie M.
Published: June 2020

Background

Circulating galectin‐3 levels provide prognostic information in patients with established heart failure (HF), but the associations between galectin‐3 levels and other incident cardiovascular events in asymptomatic individuals at midlife and when remeasured ≈15 years later are largely uncharacterized.

Methods and Results

Using multivariable Cox proportional hazards models, we identified associations between plasma galectin‐3 levels (hazard ratio [HR] per 1 SD increase in natural log galectin‐3) and incident coronary heart disease, ischemic stroke, HF hospitalization, and total mortality in ARIC (Atherosclerosis Risk in Communities) participants free of cardiovascular disease at ARIC visit 4 (1996–1998; n=9247) and at ARIC visit 5 (2011–2013; n=4829). Higher galectin‐3 level at visit 4 (median age 62) was independently associated with incident coronary heart disease (adjusted HR, 1.30; 95% CI, 1.06–1.60), ischemic stroke (HR, 1.42; 95% CI, 1.01–2.00), HF (HR, 1.44; 95% CI, 1.17–1.76), and mortality (HR, 1.56; 95% CI, 1.35–1.80). At visit 5 (median age, 74), higher galectin‐3 level was associated with incident HF (HR, 1.93; 95% CI, 1.15–3.24) and total mortality (HR, 1.70; 95% CI, 1.15–2.52), but not coronary heart disease or stoke. Individuals with the greatest increase in galectin‐3 levels from visit 4 to visit 5 were also at increased risk of incident HF and total mortality.

Conclusions

In a large, biracial community‐based cohort, galectin‐3 measured at midlife and older age was associated with increased risk of cardiovascular events. An increase in galectin‐3 levels over this period was also associated with increased risk.
AKAP12 Signaling Complex: Impacts of Compartmentalizing cAMP‐Dependent Signaling Pathways in the Heart and Various Signaling Systems
Authors: Qasim Hanan , McConnell Bradley K.
Published: June 2020

Heart failure is a complex clinical syndrome, represented as an impairment in ventricular filling and myocardial blood ejection. As such, heart failure is one of the leading causes of death in the United States. With a mortality rate of 1 per 8 individuals and a prevalence of 6.2 million Americans, it has been projected that heart failure prevalence will increase by 46% by 2030. Cardiac remodeling (a general determinant of heart failure) is regulated by an extensive network of intertwined intracellular signaling pathways. The ability of signalosomes (molecular signaling complexes) to compartmentalize several cellular pathways has been recently established. These signalosome signaling complexes provide an additional level of specificity to general signaling pathways by regulating the association of upstream signals with downstream effector molecules. In cardiac myocytes, the AKAP12 (A‐kinase anchoring protein 12) scaffolds a large signalosome that orchestrates spatiotemporal signaling through stabilizing pools of phosphatases and kinases. Predominantly upon β‐AR (β
2
‐adrenergic‐receptor) stimulation, the AKAP12 signalosome is recruited near the plasma membrane and binds tightly to β‐AR. Thus, one major function of AKAP12 is compartmentalizing PKA (protein kinase A) signaling near the plasma membrane. In addition, it is involved in regulating desensitization, downregulation, and recycling of β‐AR. In this review, the critical roles of AKAP12 as a scaffold protein in mediating signaling downstream GPCRs (G protein–coupled receptor) are discussed with an emphasis on its reported and potential roles in cardiovascular disease initiation and progression.
Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams
Authors: Wira Charles R. , Goyal Mayank , Southerland Andrew M. , Sheth Kevin N. , McNair Norma D. , Khosravani Houman , Leonard Anne , Panagos Peter ,   on behalf of the AHA/ASA Stroke Council Science Subcommittees: Emergency Neurovascular Care (ENCC), Telestroke and the Neurovascular Intervention Committees; and on behalf of the Stroke Nursing Science Subcommittee of the AHA/ASA Cardiovascular and Stroke Nursing Council
Published: June 2020

The coronavirus disease 2019 (COVID-19) pandemic has in some regions overwhelmed the capacity and staffing needs of healthcare systems, necessitating the provision of resources and staff from different disciplines to aid COVID treatment teams. Stroke centers have multidisciplinary clinical and procedural expertise to support COVID treatment teams. Staff safety and patient safety are essential, as are open lines of communication between stroke center leaders and hospital leadership in a pandemic where policies and procedures can change or evolve rapidly. Support needs to be allocated in a way that allows for the continued operation of a fully capable stroke center, with the ability to adjust if stroke center volume or staff attrition requires.
Specially for Television?
Authors: Bignell Jonathan
Published: June 2020

This article analyses tensions between medium specificity and intermediality in Beckett’s first original drama for television, Eh Joe (1966), which exploits features of the medium such as the spatiality of the studio, monochrome images and close-up. But its visual motifs also echo Beckett’s cinema debut, Film (1964), and uses of sound and voice from his radio plays. The public promotion of Eh Joe centred on its relationships with Beckett’s theatre plays, while Eh Joe’s first audiences adduced frames of reference from both theatre and television. Eh Joe works with the porosity of media boundaries and performatively renegotiates them.
Samuel Beckett and Intermedial Performance
Authors: McMullan Anna
Published: June 2020

This article analyses two intermedial adaptations of works by Beckett for performance in relation to Ágnes Pethő’s definition of intermediality as a border zone or passageway between media, grounded in the “inter-sensuality of perception.” After a discussion of how Beckett’s own practice might be seen as intermedial, the essay analyses the 1996 American Repertory Company programme Beckett Trio, a staging of three of Beckett’s television plays which incorporated live camera projected onto a large screen in a television studio. The second case study analyses Company SJ’s 2014 stage adaptation of a selection of Beckett’s prose texts, Fizzles, in a site-specific, historical location in inner city Dublin, which incorporated projected sequences previously filmed in a different location, a former power station.
Intermediality and the Future Anterior
Authors: Bates Julie
Published: June 2020

This essay traces the ways in which the intermedial practices of the artist Brian O’Doherty and writer Brian Dillon cast into relief Samuel Beckett’s own intermediality, marking it as a still-relevant set of propositions for dissolving boundaries between media and posing questions about time. I propose that intermediality functions for O’Doherty as an optimistic means of opening up potential new forms and futures, but for Beckett and Dillon alike designates a negative aesthetic and political dynamic, anticipating failure even in the moment of experimentation. This time-annulling intermediality is evocative, I believe, of what Dillon describes as “a modernist future that never came to pass.”
Synopsis of Cyatheaceae from Myanmar

Authors: DONG SHI-YONG
Published: June 2020

A synopsis of Cyatheaceae from Myanmar is presented for the first time. The classification of four genera in Cyatheaceae is applied and 10 species in three genera are tentatively recognized in Myanmar based on herbarium collections and previous reports. Of the 10 recognized species, Gymnosphaera henryi and G. podophylla are confirmed for the first time with distribution in Myanmar. Some misidentifications of collections in previous reports are clarified. A key to genera and species, diagnostic characters for each species, and notes involving nomenclature and species identification are provided.
Polygonatum daminense (Asparagaceae), a new species from China based on morphological and molecular evidence

Authors: YANG HAIJUN , WU BAOHUAN , CHEN ZILIN , WANG PAN , SHI SHI , LI FEIFEI , XU HAN , CUI DAFANG
Published: June 2020

A new species of Polygonatum (Asparagaceae), P. daminense is described and illustrated from Pan’an, Zhejiang, China. The new species is similar to P. filipes, but differs from it for some features of the rhizome, the inflorescence, the peduncle, the pedicel, the bract, the bractlet and the perianth. The new species is only known from Zhejiang Province and is assessed as Data Deficient (DD).
First record of Magnospina Sousa, Elmoor-Loureiro & Santos, 2016 (Cladocera: Chydoridae: Aloninae) from tropical India
Authors: SOUSA FRANCISCO DIOGO R. , PADHYE SAMEER M.
Published: June 2020

David Frey raised the hypothesis of non-cosmopolitanism in Cladocera in a series of his publications (Frey 1982, 1987). Since then, researchers have taken the effort to revise species groups with wide geographic distribution around the world (e.g. Kotov & Dumont 2000; Sinev 2015; Van Damme & Dumont 2008a; Sinev & Elmoor-Loureiro 2009). The polyphyletic nature of the genus Alona Baird, 1843 (Van Damme et al. 2010) has further substantiated the view that cladocerans are non-cosmopolitan, with the creation of many new genera to accommodate the several species groups known within this genus (Van Damme & Dumont 2008b; Sinev & Kobayashi 2012; Van Damme & Dumont 2009; Alonso & Sinev 2019).
New species of Augochlora (Oxystoglossella) Eickwort (Hymenoptera; Apoidea) from Northeastern Brazil with an identification key for the region
Authors: LEPECO ANDERSON , GONÇALVES RODRIGO BARBOSA
Published: June 2020

Within Augochlorini, Augochlora Smith is one of the most speciose genera, with 118 species, and widely distributed groups, occurring from Argentina to Canada. The genus has a remarkable range of social behaviors and nesting substrate preferences. There are two recognized extant subgenera: Augochlora s.s., whose species nest in decaying wood cavities and Oxystoglossella, whose species nest in soil. To date, a single species revision is available for Central Argentina and Uruguay. In the present study we provide a revision of Oxystoglossella species occurring in Northeastern Brazil including the description of three new species: Augochlora bipunctata sp. nov., Augochlora modica sp. nov. and Augochlora tenax sp. nov. Herein Halictus eucnemis Vachal is resurrected from synonymy with Augochlora thalia Smith, and the lectotype of Halictus hemitomes Vachal is presently designated. Augochlora aurinasis is cited for Brazil for the first time. A key to the six species of Oxystoglossella occurring at Northeastern region in Brazil is provided. The three new species are apparently restricted to this region, being one of them probably linked to the Caatinga biome.
Recent collections of sea spiders (Arthropoda: Pycnogonida) from China seas, with some new records and a checklist of the area
Authors: WANG JIANJIA , LIN HESHAN , HUANG DINGYONG , ZHENG XINQING , LIU QINGHE , WANG JIANJUN , NIU WENTAO , ZHANG FENG
Published: June 2020

Though research about sea spiders limited in China seas, a complete checklist has not yet exist so far. After checking recent collections obtained from Shandong, Zhejiang, Fujian and the East China Sea, all these sixty-eight specimens were identified as six species belonged to four families and five genera, including three ones new to China. We described and illustrated them in this study, and also revised all previous records about Chinese pycnogonids and provided a checklist for the presently known forty-one species.
A Peculiar Stimulatory Effect of Acetic Acid on Ethanol Fermentation of Saccharomyces cerevisiae
Authors: Zhang Jianhua , Yang Xinchao , Wang Ke , Wang Huijun , Xue Hongguang , Mao Zhonggui
Published: June 2020

In the integrated ethanol-methane fermentation process, acetic acid was accumulated once the process runs badly. Ethanol production per DCW (dry cell weight) was increased when low concentrations of acetic acid was present, where glycerol yields significantly decreased. To explain it,
we monitored intracellular energy factors (ATP, ADP and AMP) and cofactors (NAD+, NADH and NADP) at pH 4.5. In the presence of 60 mM acetic acid at pH 4.5, ATP per unit DCW increased by 47.52% compared to the control, while NADH per unit DCW decreased by 38.64%. Furthermore, in
the presence of 90 mM acetic acid, the trehalose per unit DCW increased by 55.81% compared to the control. In addition, the fluorescence intensity of membrane potential increased along with the increase of acetic acid. So the positive effect of acetic acid on ethanol fermentation made the
integrated process more applied.
Encounters in a marginalised subject: The experiential challenges faced by Tasmanian Health and Physical Education teachers
Authors: Cruickshank Vaughan , Hyndman Brendon , Patterson Kira , Kebble Paul
Published: June 2020

Subjects such as Health and Physical Education (HPE) can be marginalised in schools because they are construed as less academically rigorous and less important to the primary mission of education. Teachers of all subjects face challenges, yet, teaching a marginalised subject can result in additional challenges for HPE teachers. Previous research has noted these challenges; however, less is known about how these challenges vary according to student age and teacher experience. This study used quantitative survey methods to ascertain which challenges are the most difficult for Australian HPE teachers, and whether this difficulty varies according to their teaching experience and the ages of their students. Findings indicated that the year level of students taught by HPE teachers was significantly associated with student engagement and isolation within their schools. Years of teaching experience was significantly associated with challenges in teaching students with special needs, with more experienced teachers rating this area as less of a challenge than less experienced teachers.
The influence of grid connection of electric vehicles on microgrid and its coordinated control under the background of new energy power generation
Authors: Liu Jijun
Published: June 2020

To explore the influence of grid connected electric vehicle on microgrid and its collaborative control under the background of new energy power generation, in this study, the constraints of electric vehicle are established from two aspects of electric vehicle travel characteristics and battery charging and discharging characteristics. In view of the variety of controllable resources in microgrid, multi-agent microgrid coordination control architecture is used to control the multi-layer coordination of microgrid, and simulation is built to analyze four different scenes. The results show that in the microgrid load, it is found that the valley peak difference is the smallest when both the electric vehicle and the conventional load participate in the demand response (scene 4). In the change of SOC and charge discharge power of battery energy storage system, it is found that four scenes make the energy storage function of “low storage and high generation” play an effective role. In the economic and environmental benefits of microgrid daily operation, it is found that the daily operation cost and environmental benefits of scene 4 are significantly lower than that of scene 1. Therefore, in this study, the coordinated optimization method of integrating electric vehicle into microgrid based on multi-agent microgrid can effectively solve the coordinated optimization of multi controllable resources of microgrid, and provide experimental basis for the subsequent development and optimization of microgrid.
mHealth for schizophrenia spectrum disorders management: A systematic review
Authors: Chivilgina Olga , Wangmo Tenzin , Elger Bernice Simone , Heinrich Thomas , Jotterand Fabrice
Published: June 2020

Background:

Various types of computational technologies can be used to access, store and wirelessly share private and sensitive user-related information. The ‘big data’ provided by these technologies may enable researchers and clinicians to better identify behavioral patterns and to provide a more personalized approach to care. The information collected, however, can be misused or potentially abused, and therefore could be detrimental to the very people who provided their medical data with the hope of improving care. This article focuses on the use of emerging mobile technologies that allow the collection of data about patients experiencing schizophrenia spectrum and related disorders. Schizophrenia has been recognized by the Sustainable Development Goals of the United Nations for its burden on our health care system and society [1]. Our analysis provides an overview of the range of available mobile technologies for people with schizophrenia and related conditions along with the technology’s reported capabilities and limitations, and efficacy of mHealth interventions based on the data from articles. Thus, the focus of this review is first and foremost to update the scope of existing technologies as previous systematic reviews such as the ones by Alvarez-Jimenez et al. and by Firth and Torous are outdated [2, 3]. Although we also examine the ethical issues arising from the use of these technologies, for an in-depth analysis of the ethical implications of mobile Health technologies (mHealth), we refer the readers to our follow-up article. In terms of the ubiquitous availability of technology on the internet, our article summarizes significant information for mental health specialists and apprises the reader about the existence of these technologies.

Objectives:

In terms of the ubiquitous availability of technology on the internet, our article summarizes significant information for mental health specialists and apprises the reader about the existence of these technologies.
Turning Complaining Customers into Loyal Customers: Moderators of the Complaint Handling–Customer Loyalty Relationship
Authors: Morgeson Forrest V. , Hult G. Tomas M. , Mithas Sunil , Keiningham Timothy , Fornell Claes
Published: June 2020

Firms spend substantial resources responding to customer complaints, and the marketing profession has a long history of supporting that enterprise to promote customer loyalty. The authors question whether this response is always warranted or whether its effectiveness instead depends on economic, industry, customer–firm, product/service, and customer segment factors that may alter the firm’s incentives to compete on complaint management. To consider this question, they integrate economic and marketing theories and investigate factors that influence the complaint recovery–customer loyalty relationship via a sample of 35,597 complaining customers spanning a ten-year period across economic sectors, industries, and firms. Overall, the authors find that the recovery–loyalty relationship is stronger in faster-growing economies, for industries with more competition, for luxury products, and for customers with higher satisfaction and higher expectations of customization. Conversely, the recovery–loyalty relationship is weaker when customers’ expectations of product/service reliability are higher, for manufactured goods, and for men compared with women. The authors discuss implications of these results for managers, policy makers, and researchers for more effective management of customer complaints.
The Attitudes of Progressive Neurological Disease Patients and Their Family Members to End of Life Care: A Cross-Sectional Study
Authors: Bužgová Radka , Kozáková Radka , Bar Michal , Škutová Monika , Ressner Pavel , Bártová Petra
Published: June 2020

The objective was to identify the attitudes of progressive neurological disease (PND) patients and their family members regarding end-of-life care, and their worries about dying. The sample included 327 participants. The Attitudes of Patients with PND to End-of-Life Care questionnaire was used to collect the data. Statistically significant differences in the assessment of attitudes towards end-of-life care between patients and family members were identified (p < 0.001). Family members more frequently favored patients being kept alive at any cost; patients more commonly wished to have their end of life under control. Respondents most frequently deferred to doctors when it came to decisions on treatment to keep patients alive. However, both patients and family members wanted patients to be able to decide on their treatment by leaving a written record of their previously stated wishes. The demands of patients and their families regarding end-of-life care should be documented in individual care plans.
Modeling perceptions using common impressions: Perceptual “authenticity,” “luxury,” and “quaintness” for leather
Authors: Watanabe Shuhei , Horiuchi Takahiko
Published: June 2020

Genuine leather has numerous applications, such as car interiors and clothing, owing to its excellent quality. However, due to the high cost of genuine leather, animal rights issues, and environmental effects of leather processing, artificial leather has increasingly replaced genuine leather. The materials and processing methods used for artificial and genuine leathers are different, resulting in a variety of impressions and shitsukan, that is, the sense of quality of the object. In this study, we focused on the perceptual “authenticity,” “luxury,” and “quaintness,” which are important components needed to achieve the shitsukan of leather used in various products and examined the quantification of qualitative shitsukan using a perception model. We hypothesized that shitsukan can be recognized from the common potential impressions perceived from the properties of a material. Therefore, we developed a method for evaluating shitsukan using representative words for impressions that we perceive in objects and measured their image properties. The physical and psychophysical properties were obtained using several measurements. Multi-angle measuring devices were developed for the measurement experiments. Moreover, several subjective evaluation experiments were conducted to estimate the representative impressions that were potentially perceived in leather. Subsequently, we estimated two independent impressions, “surface shape” and “impression of stateliness” from the properties of leather. In addition, “authenticity,” “luxury,” and “quaintness,” were quantified using simple equations basis the impressions.
The role of clubfoot training programmes in low- and middle-income countries: a systematic review
Authors: Sheik-Ali Sharaf , Navarro Sergio M , Keil Evan , Lavy Chris
Published: June 2020

While adoption of the Ponseti method has continued gradually, its use to manage patients with congenital talipes equinovarus (CTEV) has been limited in low- and middle-income countries (LMICs) for a number of reasons including a lack of clinical training on technique and lack of appropriate clinical equipment. There are a frequent number of emerging studies that report on the role of clubfoot training programmes; however, little is known in regard to cumulative benefits.

A systematic review was undertaken through Medline, the Cochrane Library and Web of Science for studies analysing clubfoot training programmes. There were no limitations on time, up until the review was commenced on January 2020. The systematic review was registered with PROSPERO as 165657. Ten articles complied with the inclusion criteria and were deemed fit for analysis. Training programmes lasted an average of 2–3 days. There was a reported increase in knowledge of applying the Ponseti method in managing clubfoot by participants (four studies P < 0.05). Skill retention was examined by multiple choice (MCQ) examination style questions before and after the training programme in two studies; both showed an improvement (MCQ answers improved from 59% to 73%). All studies showed an improvement in participants' self-reported understanding of the Ponseti method and confidence in its use in future practice ( P < 0.05). There were improved benefits of knowledge and clinical application of the Ponseti method by participants in the programmes in all studies examined. However, there was a significant lack of follow-up and exploration of long-term effects of these programmes. Implementing training programmes based on perceived benefits rather than actual long-term benefits may have a negative impact on healthcare delivery and patient management in LMICs.
LMX Differentiation and Group Outcomes: A Framework and Review Drawing on Group Diversity Insights
Authors: Buengeler Claudia , Piccolo Ronald F. , Locklear Lauren R.
Published: June 2020

In this review, we address inconsistencies and a lack of clarity in the study of leader-member exchange (LMX) differentiation and group outcomes. We do so by drawing on another highly visible group dispersion literature in the management domain, group diversity, based on the recognition that LMX quality is a characteristic on which group members vary. Utilizing insights from Harrison and Klein’s typology of group diversity constructs, we introduce a framework that specifies the meaning and shape of three variations of differentiated leader-member relationships in groups and connects each construct with implications in terms of theorizing and measurement. Specifically, our framework conceptualizes LMX differentiation as LMX separation (dispersion in LMX relationships as disagreement or opposition regarding an opinion, perception, or position), LMX variety (dispersion in LMX relationships as distinctiveness in kind, source, or category), and LMX disparity (dispersion in LMX relationships as inequality in concentration of valued social assets or resources). We then apply this framework to conduct a systematic review of the LMX differentiation literature with particular attention to alignment among a study’s descriptions of the construct, application of theory, expected group outcomes, and construct measurement. Finally, we offer recommendations for future research and for applying our framework to enhance reliability, validity, and generalizability in studies of LMX differentiation and group outcomes.
The impact of semantic annotation techniques on content-based video lecture recommendation
Authors: Dias Laura Lima , Barrére Eduardo , de Souza Jairo Francisco
Published: June 2020

Increasing videos available in educational content repositories makes searching difficult, and recommendation systems have been used to help students and teachers receive a content of interest. Speech is an important carrier of information in video lectures and is used by content-based video recommendation systems. Although automatic speech recognition (ASR) transcripts have been used in modern video recommendation systems, it is not clear how annotation techniques work with noisy text. This article presents an analysis on a set of semantic annotation techniques when applied to text extracted from video lecture speech and their impact on two tasks: annotation and similarity analysis. Experiments show that topic models have good results in this scenario. Besides, a new benchmark for this task has been created and researchers can use it to evaluate new techniques.
Affective Control in New Collaborative Work: Communal Fantasies of Purpose, Growth and Belonging
Authors: Resch Bernhard , Hoyer Patrizia , Steyaert Chris
Published: June 2020

We examine the increasing popularity of collaborative work to understand the consequences of these practices for organizational control. Applying a Lacanian framework, we pay attention to how this (re-)emerging trend of collaborative work is underpinned by affect-laden fantasies of community-driven co-creation. Based on a multi-source study design to explore collaborative work, we identified three interrelated fantasies that arouse passionate attachments to collaborative community involvement: a spiritual fantasy of ‘purpose’, an entrepreneurial fantasy of ‘growth’ and a tribal fantasy of ‘belonging’. To preserve the relevance of Lacan’s thought for the inquiry of distributed, post-heroic and post-hierarchical work practice, we propose the notion of ‘communal Other’. This notion provides insights into the unfolding of control through the fantasmatic desire for wholeness by working in collaborative communities. Conceptually, we theorize how tensions between the paradoxical enjoyment of pleasure and pain – what Lacan called ‘jouissance’ – highlight the central importance of affective control in collaborative work.
A Dyadic Study on Perceived Stress and Couple Adjustment During Pregnancy: The Mediating Role of Depressive Symptoms
Authors: Baldoni Franco , Giannotti Michele , Casu Giulia , Luperini Valerio , Spelzini Federico
Published: June 2020

Stress is associated with dyadic adjustment during transition to parenthood, but little is known about mechanisms underlying this link, particularly during prenatal period. This dyadic study explored the mediating role of depressive symptoms in the relationship between perceived stress and dyadic adjustment in expectant couples. One hundred and fourteen couples at the third trimester of pregnancy completed self-reports of perceived stress, depression, and dyadic adjustment. Results indicated that both parents’ perceived stress was associated with their own lower relationship satisfaction directly and indirectly, through their own higher depressive symptoms. Mothers’ perceived stress was also linked to higher fathers’ depressive symptoms, and thus also to lower fathers’ relationship satisfaction. Both parents’ perceived stress was only directly associated with their own dyadic consensus, and their own and their partners’ affectional expression. Findings suggest that interventions aimed at reducing expectant parents’ perceived stress could protect against depressive symptoms and promote the couple’s adjustment during pregnancy.
Cricopharyngeal Achalasia: Management and Associated Outcomes—A Scoping Review
Authors: Dewan Karuna , Santa Maria Chloe , Noel Julia
Published: June 2020

Objective

There is little consensus regarding the efficacy and safety of treatment options for cricopharyngeal (CP) achalasia. The purpose of this scoping review is to assess the literature regarding the various treatments for this disease.

Data Sources

PubMed was searched for all articles addressing treatment of adult CP achalasia between January 1990 and June 2019.

Review Methods

In total, 351 peer‐reviewed results were reviewed by 3 otolaryngologists for inclusion. After review of titles, abstracts, and full texts, 60 articles were selected.

Results

Among included studies, 55% were retrospective and 45% were prospective. Forty‐five percent of studies were case series. CP achalasia etiologies included idiopathic (28%), cerebrovascular accident (CVA) (28%), neurologic disease (17%), head and neck radiation treatment (11%), Zenker’s diverticulum (10%), and myositis (5%). Most commonly employed treatments were botulinum toxin injection (40%), endoscopic CP myotomy (30%), dilation with either balloon or bougie (25%), and open CP myotomy (15%). A proportion of patients were treated with more than 1 approach. Most studies included both subjective and objective outcome measures. Complications were reported most often in patients with a history of head and neck radiation.

Conclusions

Small sample sizes and heterogeneity of causes and treatments of CP achalasia, as well as short duration of follow‐up, make it challenging to assess the superiority of one treatment over another. There is a need for a prospective study that more directly compares outcomes of administration of botulinum toxin, dilation, and CP myotomy in patients with CP achalasia of similar etiologies.
Meta‐analysis Exploring Sinopulmonary Outcomes of Aspirin Desensitization in Aspirin‐Exacerbated Respiratory Disease
Authors: Chaaban Mohamad R. , Moffatt David , Wright Alex E. , Cowthran James A. , Hsu En Shuo , Kuo Yong‐Fang
Published: June 2020

Objective

The objective of this study is to explore the sinopulmonary outcomes of aspirin desensitization through a systematic review and meta‐analysis.

Data Sources

Embase and OVID Medline databases.

Review Methods

A systematic review of published articles on outcomes following aspirin desensitization in any language for relevant articles was performed in February 2019. Outcomes included sinonasal quality‐of‐life assessment, sense‐of‐smell scores, FEV‐1 (forced expiratory volume in 1 second), and medication/steroid use.

Results

Thirteen studies met the inclusion criteria out of 6055 articles screened. Aspirin desensitization resulted in significant improvement in FEV‐1 and reduction in asthma medication/steroid use (P <. 05). There was no significant improvement in the sinonasal quality of life of patients who underwent aspirin desensitization (P =. 098).

Conclusion

Aspirin desensitization appears to be effective in improving pulmonary outcomes and should be considered in the treatment of patients with aspirin‐exacerbated respiratory disease. However, good‐quality studies are still needed to determine the ideal protocol tailored to individual patients.
Identifying Type III Sulcus: Patient Characteristics and Endoscopic Findings
Authors: Varelas Eleni A. , Paddle Paul M. , Franco Ramon A. , Husain Inna A.
Published: June 2020

Objective

Type III sulcus is a pathologic structural deformity of the vocal folds that is challenging to accurately diagnose without endoscopic examination under anesthesia. This study aims to further define the clinical presentation and examination features shared among a patient cohort intraoperatively diagnosed with type III sulcus.

Study Design

Case series with chart review.

Setting

Tertiary laryngology practice.

Subjects and Methods

All patients diagnosed intraoperatively with type III sulcus from 2002 to 2014 at a tertiary laryngology practice were included. Clinical history of presenting symptoms, videostroboscopy, and intraoperative and histologic findings were reviewed.

Results

Twenty‐two patients were included in the study. A majority were female (77%) and had a mean age of 32.4 years. All patients endorsed hoarseness, and 86% were defined as professional voice users. Endoscopic examination revealed bilateral type III sulcus in 23% of patients. The most common preoperative stroboscopic findings included decreased mucosal wave (100%), dilated vessel (95%), phase asymmetry (91%), additional benign lesion (91%), and cyst (82%). Histology revealed epithelial changes of atypia and keratosis.

Conclusion

Both the severity of dysphonia and the difficulty observing structural malformations of the vocal folds make type III sulcus challenging to preoperatively diagnose. This study reports the clinical and endoscopic features seen within a cohort of patients with type III sulcus.
Real-time ultrasound-guided bedside closure of arteriotomy wound using MANTA closure device during venoarterial extracorporeal membrane oxygenation decannulation
Authors: Au Shek-Yin , Fong Ka-Man , Ng Wing-Yiu George , Lee Kang-Yin Michael , So Sheung-On , Leung Kit-Hung Anne
Published: June 2020

Percutaneous closure of arteriotomy wound during peripheral venoarterial extracorporeal membrane oxygenation decannulation was shown to be safe and allow earlier mobilization. The new MantaTM vascular closure device (Essential Medical), designed for the closure of arterotomy wound created by large-bore vascular sheaths up to 25Fr during endovascular catheterization procedures, was reported to be applicable in venoarterial extracorporeal membrane oxygenation decannulation. In this article, we would like to share our experience of using real-time ultrasound guidance to ensure the safe application of Manta during bedside venoarterial extracorporeal membrane oxygenation decannulation.