bluuebunny/crossref_metadata_2025 huggingface dataset:
Paixão e loucura nos limites da clínica psicanalítica
Authors: Hoffmann Azevedo Berta
Published: February 2025

A autora aborda as aproximações entre paixão e loucura, destacando o vínculo com a experiência primordial de indiscriminação e transbordamento que toca a ambas. Aponta, além disso, os efeitos das estratégias de conjuração dessas vivências na clínica limite. A partir da experiência clínica de transferência passional desencadeada pelo efeito desorganizador de uma paixão amorosa, a autora utiliza contribuições de Freud, André Green, Piera Aulagnier, Joyce McDougall e J.-B. Pontalis, e as articula com as obras literárias Paixão simples, de Annie Ernaux, e Bartleby, de Herman Melville.
Psicanálise, ciência e teoria da ciência. Parentes, amigas ou estranhas?
Authors: Sandler Paulo Cesar
Published: February 2025

O autor propõe um estudo transdisciplinar sob o vértice psicanalítico, abrangendo uma história da ideias na civilização e a teoria da ciência, para considerar algumas origens sociais e intrapsíquicas dos investigadores na ciência e na psicanálise. Seu intuito é firmar com menor imprecisão a qualificação científica da psicanálise, periodicamente questionada, tanto por acadêmicos quanto, na atualidade, por membros do movimento psicanalítico.
The Study of Verbal Exegesis by Tuan Guru Hasanain on the Environment
Authors: Zulkarnaen  , Hamzah Idil
Published: February 2025

This article will discuss fiqh al-bi’ah as an offer of Islamic concepts against the ecological crisis. Global societies today face environmental crises, global warming, climate change, droughts, and other ecological problems. Conscious or not, humans are the main perpetrators of the destruction of the living environment by exploiting natural resources. This paper is intended to find a way out of the ecological crisis through the approach of the Fiqh al-bi’ah paradigm. It is especially important for Muslims to have a legal foundation that can serve as a foundation for thinking and acting in dealing with environmental issues. This writing is a library study whose data is obtained from some literature in particular that offends the environmental issues of living. More specifically, this research will use the maslahat approach in the theory of Islamic law. To deepen his study, the article will also look at the classic and contemporary fiqh paradigms. As the findings of the article show, it turns out there are quite significant differences between the paradigms of the classic fiqh concepts and the contemporary-related fiqh al-bi'ah. Through this article, I argued that keeping the environment could be considered one of the Maqasid al- Syari'ah.
Ecotheological Exegesis: a Study of Indonesian Women’s Ulema Congress Opinion
Authors: Moh. Rofqil Bazikh
Published: February 2025

Environmental damage is a problem which gets attention even religionist regards about it. The interpretation of Koran verses presents to elaborate the ethical principle for nature and environment. One of the groups which attempts to interpret ecological verses within Koran is Indonesian Women’s Ulema Congress (KUPI). This congress held firstly in 2017 and then 2022. In first congress, KUPI discussed three crucial issues from sexual abuse, child marriage until damage of nature. This research aims to analyze KUPI interpretation regarding environmental demage. The type of research is qualitative based on library research (kajian pustaka). The data are gathered from literatures which are relevant with the topic. Primary source is earned from Result and Process Document of Indonesian Women’s Ulema Congress (KUPI) I in 2017. Secondary sources are earned from literature, journal, article, book, which relate with topic of environment and ecotheology. This research uses analytical descriptive which analyzes the content such as in primary source. To analyze the finding of research uses ecotheology concept initiated by Seyyed Hossein Nasr and Mary Evelyn Tucker. There are phases in this research from collecting, identifying, analyzing and concluding the data based on the theoretical framework. The conclucion that KUPI interpretation on Koran verse is ecotheological such as Nasr and Tucker perception. There are nineteen verses which are elaborated to support contrary position toward environmental demage. Some of KUPI interpretations are more progressive than interpretation in classical exegesis.
Nature as Evidence: On Ibn Rushd's Theorems for God's Existence
Authors: Alya Mumtaza Hafidz
Published: February 2025

The complexity of nature and its beauty have been inspiring some philosophers to postulate argument for God’s existence. In his endavour to comment on mutakallimun’s argumentations, which contained with many falsehood, Ibn Rushd offerred two simple alternative theorems that he deduced from Quranic verses and nature’s complexity. These theorems was shown in Kitab Al-Kasyf ‘an Manahij al-Adilla fi ‘Aqa’id al-Milla which Ibn Rushd called dalil Inayah and dalil Ikhtira. Not only came from Muslim side, these theorems apparently have some similarity with argumentations that proposed by Western thinkers in modern era; argument from Anthropic principles and William Paley’s Watchmaker argument. Based on those similarity, this research aims to compare and to show some logical fallacies along with objections toward Ibn Rushd’s theorems and Western thinker’s arguments. Through library research, researchers have found some weakness in both type of arguments; such as fallacy of false cause, special pleading fallacy, false analogy, and even emerged bigger consequence from the problem of evil. With these flaws and logical fallacies, Ibn Rushd’s theorems and Western’s argumentations for God’s existence that based on nature’s empirical evidences should not be sustained any longer.
The Analysis Study of Diagnostic Imaging Performance and Accuracy of Congestive Heart Failure: A Comprehensive Systematic Review
Authors: Mutiara Nurul Mahabbah  , Rendi Rafsanjani  , Bintara Ayu Putri
Published: February 2025

Background: Congestive heart failure (CHF) diagnosis requires accurate imaging techniques like echocardiography, magnetic resonance imaging (MRI), and computed tomography (CT). However, challenges persist in diagnostic accuracy due to factors like operator dependency and radiation exposure. This review aims to systematically evaluate the performance and accuracy of various diagnostic imaging modalities in the context of CHF. Methods: This systematic review adhered to PRISMA 2020 guidelines, focusing exclusively on full-text articles published in English between 2014 and 2024. Editorials and review articles without a DOI were excluded to ensure the utilization of high-quality sources. A literature review was conducted utilizing reputable databases including ScienceDirect, PubMed, and SagePub to identify relevant studies. Result: The initial database search identified over 1,000 relevant publications. Through a rigorous three-stage screening process, eight studies met the predefined inclusion criteria for in-depth analysis. Each study underwent a comprehensive critical evaluation, ensuring a high-quality evidence base for assessing the diagnostic imaging performance and accuracy in congestive heart failure. This systematic approach strengthened the study’s relevance, providing meaningful insights into the strengths and limitations of various imaging modalities. Conclusion: Echocardiography, cardiac CT, and cardiac MRI are essential imaging modalities for diagnosing and managing CHF. Echocardiography offers real-time imaging, while cardiac CT provides high-resolution insights. MRI, the gold standard for myocardial tissue characterization, offers unparalleled prognostic value. Integrating these technologies enhances patient outcomes.
DECHETS SOLIDES MENAGERS A KINSHASA : OPPORTUNITES ET MENACES POUR L’ENVIRONNEMENT ET LA POPULATION SOLID HOUSEHOLD WASTE MANAGEMENT IN KINSHASA: OPPORTUNITY OR THREAT FOR THE ENVIRONMENT AND THE POPULATION
Authors: Masamuna Parfait , Vuni Alexis , Mwen Abel , Iyolo Fabrice , Bifubiambote Giresse , Nzo Godefroid
Published: February 2025

The growth of the urban population and the constant expansion of the space occupied are major challenges for environmental management in Kinshasa. The main aim of this study is to analyse waste management methods and their impact on the environment. Specifically, it aims to: (i) check the type of waste in bins and illegal dumps, analyse waste disposal methods, (ii) check whether households sort waste before putting it in the bin. A survey was carried out in four communes, with households selected at random. The data collected was analysed using Epidtat 3.0, Microsoft Excel 2013 and SPSS 20 software. The results showed that in the communes studied, 85% of households in Lemba, 70% in Ndjili, 80% in Matete and 20% in Kisenso used private collection (trolleys, pushcarts). On the other hand, 10% in Kisenso, 9% in Matete, 10% in Ndjili and 5% in Lemba use collection by ONGD. As for self-disposal, 70% in Kisenso, 11% in Matete, 20% in Ndjili and 10% in Lemba. These practices do not reflect urban realities. However, taking advantage of a general state of urban disorder, they persist and reproduce themselves, sometimes with worrying environmental and health repercussions. Thanks to our various field surveys, we were able to identify the different waste management methods used by households
ANALYSIS OF THE BEHAVIOR OF HYPERPARAMETERS OF THE SVM ALGORITHM FOR THE PREDICTION OF PROTEIN STRUCTURES IN NON-HOMOLOGOUS DATA SETS
Authors: Mukanya Benjamin , Mvumbi Georges , Kafunda Pierre , Bikandu Blaise , Ngbolua Jean Paul , Kasoro Nathanaël
Published: February 2025

One of the major challenges in bioinformatics is the prediction of protein secondary structures, which must take precision into account in order to make the understanding of protein function and interactions fluid. In this study, we analyze the hypeparameter behavior of the SVM (Support Vector Machine) algorithm for protein secondary structure prediction from non-homologous datasets. The aim is to optimize the fit of the various SVM hyperparameters such as kernel, regularization parameter C and gamma γ in order to improve accuracy and verify the impact of these combinations in the overall model. We used cross-validation and grid search techniques to facilitate the model's performance, and performed a thorough analysis of the results using metrics such as precision, accuracy, recall and F1-Score while developing suitable visualizations to see how the model performs. The results indicate that using the right combination of hyperparameters can potentially improve model performance. With regard to the choice of hyperparameters in SVM models in bioinformatics, this study highlights their importance particularly for non-homologous datasets in which highly variable sequences are often found.
MENGHADAPI TANTANGAN HIDUP DENGAN CINTA: Pelayanan Konseling Pastoral Dan Pendekatan Humanistik Terhadap Dinamika Sosial Autis
Authors: Heydemans Nency Aprilia , Salindeho Veibe , Kasalang Incha , Kahimpong Monika , Nani Deissy Christi
Published: February 2025

Penelitian ini bertujuan untuk memahami dinamika sosial anak-anak autis dan penerapan pelayanan konseling pastoral dengan pendekatan humanistik di Panti Sosial Disabilitas Victoria. Dengan fokus pada pengalaman dan kebutuhan anak-anak autis serta keluarga mereka, penelitian ini memberikan wawasan mendalam tentang bagaimana pendekatan humanistik dapat mempengaruhi kesejahteraan dan perkembangan mereka. Metode yang digunakan mencakup wawancara mendalam dengan orang tua, pengasuh, dan konselor, observasi interaksi di panti, serta analisis dokumentasi terkait autisme dan konseling pastoral. Temuan penelitian menunjukkan bahwa faktor penyebab autisme seperti genetik, biologis, dan lingkungan mempengaruhi dinamika sosial anak, serta bahwa pendekatan humanistik dalam konseling pastoral dapat membantu meningkatkan kualitas hidup anak-anak autis dan mendukung keluarga mereka secara emosional dan spiritual. Kesimpulan dari penelitian ini adalah bahwa integrasi pendekatan humanistik dalam pelayanan konseling pastoral efektif dalam mengatasi tantangan yang dihadapi anak-anak autis dan keluarga mereka, serta memperkuat komunitas yang lebih inklusif dan empatik. Penelitian ini bermanfaat untuk pengembangan praktik konseling pastoral yang lebih adaptif dan komprehensif dalam konteks autisme.
Nutritional Value of Selected Indigenous Vegetables of Cordillera
Authors: Lirio Lorenza G. , Pladio Luisa P. , Paing Joyce N. , Ayyokad L. O.
Published: February 2025

Survey on indigenous vegetables was undertaken through a partici-patory approach with the local folks who were asked about traditional food plants that are found growing in their areas in Benguet including Baguio City and in Mountain Province. Forty-nine indigenous vegetables (IVs) were documented belonging to 31 genera and distributed to 23 plant families.
Selected widely eaten indigenous vegetables such as: Amaranthus blitum, Bidens pilosa,, Cardamine hirsuta Cestrum nocturnum,, Crassocephalum crepidioides, Passiflora edulis, Pteridium aquilinum, Rorippa indica, Solanum nigrum, and Sonchus arvensis were subjected to chemical analyses to determine the proximate and vitamin contents which will give idea to the consumers of what nutrients they really get when they eat these crops. The analyses revealed that the chemical contents of IVs were comparable and some are even higher when compared to the cultivated crop Brassica chinensis that was used as a control plant.
Secularization of the Sacred: "Bendian" Through the Passage of Time
Authors: Awas Filmore Y.
Published: February 2025

This study is designed to document how Bendian evolved from a ritual to what is now called as “staged performance” and how cultural integrity and community development was promoted though its staging. It is therefore intended to look into the process of community dialogue leading to community action that affects the welfare of the community especially in terms of the maintenance of cultural integrity and the promotion of tourism. The study is limited to the documentation of the experiences and processes.
Findings show that the process of dialogue that the community people continuously observed determined the evolution of Bendian with the following enabling factors: politics, education, economic condition of the community, and tourism. The staging of Bendian provided an avenue for exchange of ideas and sharing of values, principles, characteristics and values of the community members making them feel the process of change and the process of development.
Based on the ECIP framework, the cultural integrity of the staged performance was maintained. The staging also played a big role in the intergenerational transmission of knowledge and values. Religion, education, lack of interest of the youth, lack of resources, opposition of parents, personal convictions of a member of the community, death of elders, time constraints, and lack of documentation were considered as a challenge in the development of cultural integrity in the community.
In conclusion, the evolution of Bendian from a sacred healing ritual to a secularized medium is a manifestation of a cultural change influenced by internal and external forces. The process of dialogue that the community people continuously observed, however, determines the integrity of these changes. In relation to development, it is through careful and conscious examination and understanding of these changes can the community become more able to mainstream the concept of culture into the development process.
Continuation of such practice in a form of stage performance is strongly recommended. With regards to the boundaries of change that must happen, community dialogue should be continued and properly observed together with the elders of the community. A follow-up study must also be conducted to assess the impact of cultural tourism in the municipality.
Rates of Formulated Organic Liquid Plant Supplement for Carrot (Daucus Carota) Grown in Farm Under Conversion to Organic Production
Authors: Laurean Carlito P. , Nagpala Asuncion L.
Published: February 2025

The study was conducted to develop nutrient management strategies for carrot in farms under conversion to organic production. Specifically, the study determined: 1) the effects of formulated organic liquid plant supplements on the growth and yield of carrot in farm under conversion to organic production, 2) the best rate of the formulated organic liquid plant supplements for the production of carrot in farm under conversion to organic production, and 3) the effects of the formulated organic liquid plant supplements on some physical and chemical properties of the soil in farm under conversion to organic production. The effect of the different rates of formulated organic liquid plant supplements on carrot grown in a farm under conversion to organic production differed significantly in terms of the marketable and total yield of carrots. Application of formulated organic liquid plant supplements at the rate of 70:20:10, 20:70:10, and 10:20:70 during seedling, vegetative, and root bulking stage, respectively, produced the highest marketable and total yield. Application of formulated organic liquid plant supplements significantly affected the organic matter and total nitrogen content of the soil in farm under conversion to organic production wherein the rate 80:10:10 (SS)/ 10:80:10 (VS)/ 10:10:80 (RB) resulted to the highest organic matter content of the soil after harvest. The application of formulated organic liquid plant supplements at different rates did not differ significantly in terms of plant height, insect pest infestation, and powdery mildew infection, soil bulk density, soil pH, available phosphorus content, and potassium content.
Technology Leadership and Technology Integration in Selected Science High Schools in the National Capital Region: Basis for a Proposed Online Training Module
Authors: Panganiban Rafael V.
Published: February 2025

This research assessed the extent of technology leadership of school heads and its relationship to the extent of technology integration of teachers in six selected science high schools in the National Capital Region. The study respondents were six school heads and 273 teachers. The study used validated, pilot tested and reliability-tested survey questionnaires adapted and modified from the Principals Technology Leadership Assessment and the Levels of Teaching Innovation (LoTI) Digital Age Survey. Percentage, weighted mean, Pearson correlation, chi-square, t-test, and ANOVA were used for statistical treatment. Results revealed that the school heads’ extent of technology leadership across all areas ranges from partial to full implementation, and the teachers’ extent of technology integration across all areas is being implemented “most of the time.” The school heads’ profile was not associated with their technology leadership, and only the highest educational attainment was found significantly related to the teachers’ extent of technology integration. Furthermore, the technology leadership of school heads was not significantly related to the technology integration of teachers. The study also revealed no significant differences among school heads when grouped according to their profile. There was a significant difference between teachers’ assessment of and school heads’ self-assessment of their technology leadership.
Direct Organogenesis and Regeneration of Arabica Coffee Cultivars
Authors: Dumaslan Milagros R. , Tad-awan Belinda A. , Manuel Sheryl B.
Published: February 2025

Arabica coffee is a very important crop in the Cordillera region and one of the promising industrial crops in the highlands. To develop a tissue culture protocol for ‘Typica’, ‘Mundo Novo’ and ‘Red Bourbon’ cultivars, different growth hormone combinations of Benzyl Amino Purine (BAP), Kinetin, (Kin), Indole Acetic Acid, (IAA), and 2,4-Dichlorophenoxyacetic acid (2,4-D) with different concentrations of 1, 2, 3, 4, 6 ppm/L and light conditions were tested on the somatic embryo as an explant grown in MS medium. Result showed that using somatic embryo of ‘Mundo Novo’ inoculated in 2ppm BAP and 2ppm Kinetin at 16 hours light, shoot emerged after 18.2 days and shoot proliferated with an average of 4 shoots at 91.75 days after inoculated in 2ppm BAP+ 2ppm Kin + 1ppm IAA at 24 hours light. However, 'Typica’ inoculated in 2ppm BAP, 2ppm Kin and 2ppm IAA at 24 hours light induced shoot emergence after 19 days and proliferated through direct organogenesis with an average of 5.43 shoots in 2ppm BAP +2ppm Kin + 2ppm IAA at 87.4 days after inoculation at 16 hours light condition. Subsequently, 'Red Bourbon' initiated shoot emergence after 35 days inoculated in 1ppm GA + 8ppm BA + 0.5ppm IAA in dark condition. Moreover, the regeneration of plantlets transferred to MS containing 2 ppm IBA, 2 ppm NAA and 2 ppm IAA were elongated and rooted 2-3 months after transplanting. Highest percentage of survival was recorded on 1 part of vermicompost: 1 part sand: 1 part of burnt rice hull on cultivar 'Red Bourbon' and 'Mundo Novo'. In addition, soil media with 1 part of BSU compost: 1 part sand: 1 part of burnt rice hull has a 100% survival rate on 'Typica' and 'Mundo Novo'.
Biomass, Carbon Stock, and Economic Value Assessment of Daclan Communal Forest Parcel IV in Tublay, Benguet
Authors: Bagangan Roshel B. , Carantes Nayvie N. , Taynan Ruthlane M.
Published: February 2025

Carbon stock assessment quantifies carbon stored in ecosystems, which is vital for understanding their role in sequestering carbon dioxide, informing sustainable land management crucial for human activities and climate change mitigation. Employing purposive sampling to evaluate the biomass, carbon (C) stock, and carbon dioxide (CO2) sequestered in Daclan Communal Forest, using non-destructive methods, it informs climate change monitoring, mitigation, and adaptation strategies while promoting proper forest management and sustainable development. Additionally, it underscores the potential economic value derived from the forest's carbon pools. The methodologies used include measuring trees at diameter breast height (DBH) and sampling herbaceous vegetation, litter, and soil for C content determination, using eight (8) 30m by 30m plots to gather the data and samples. The Communal Forest boasted substantial biomass totaling approximately 262 Mg ha-1, comprising 182.17 Mg ha-1 of carbon and sequestering 671.26 Mg ha-1 of CO2. This abundance holds a significant economic value estimated at Php3,038,237.09. The figures highlight the considerable role of the Communal Forest in sequestering atmospheric carbon, indicating its potential for carbon crediting and trading. Therefore, collaborative efforts from Local Government Units (LGUs), community residents, and relevant organizations are imperative for the enhancement, sustainability, and conservation of these forests.
Self-Care Practices of Miners in Sitio Midas, Itogon, Benguet
Authors: Capulong Joel A.
Published: February 2025

In the mountainous enclave of Sitio Midas, Itogon, Benguet, small-scale gold mining has sustained the community for decades, serving as the primary livelihood despite inherent health and safety risks. This qualitative research delves into the miners' perspectives on the potential hazards associated with their activities and the self-care practices they employ. Through semi-structured interviews and open-ended questions, the study actively engages miners and their families, drawing insights into their self-care strategies. Major findings underscore a heightened awareness of health risks, particularly chemical exposure, prompting the adoption of safety measures such as protective gear. Cultural influences deeply rooted in tradition significantly shape the miners' approach to self-care, with the study noting a gradual shift influenced by Christianity, supplanting long-standing customs. The miners express a dual reliance on government support, acknowledging the importance of seminars while advocating for alternative livelihood options. Despite the inherent limitations of the research, the results underscore the critical role of self-care practices in mitigating health risks within the unique context of small-scale gold mining in Sitio Midas. The conclusion highlights the resilience of miners facing environmental and health challenges and points to the need for comprehensive support systems beyond their existing efforts, indicating the broader implications for policy and intervention strategies in similar mining communities.
EXPLORING THE SYNERGISTIC ROLE OF BETA-HCG DYNAMICS AND VIRTUAL REALITY-BASED PHYSIOTHERAPY IN MANAGING PREGNANCY-RELATED PAIN
Authors: Uzair Muhammad , Bibi Khudija , Asad  , Khan Naseem , Ahmad Zahoor , Abbas Waseem , Farman Ullah
Published: February 2025

Background: During pregnancy the body of a female undergoes several hormonal and physiological changes which affect the body’s biomechanics that in turn can contribute to different musculoskeletal issues. Pregnancy-related pain, particularly pelvic girdle and lower back pain is a common concern that significantly affects quality of life. This study investigates the integration of virtual reality (VR)-based physiotherapy with an understanding of beta-human chorionic gonadotropin (beta hCG) dynamics to address this issue.
Methodology: A Quasi experimental study was conducted among pregnant participants in their second and third trimesters, comparing a VR-based physiotherapy intervention group to a standard care group. Pain intensity, measured via the Visual Analogue Scale (VAS), and functional mobility, assessed through the Timed Up and Go (TUG) test, were evaluated alongside beta hCG levels.
Results: Results demonstrated a 52.9% reduction in pain scores and a 21.6% improvement in mobility for the VR group, highlighting the efficacy of VR in altering pain perception and enhancing patient engagement. A moderate positive correlation between beta hCG levels and pain reduction was observed, suggesting hormonal influence in modulating pain and neuroplasticity.
Conclusion: This study demonstrates the potential of personalized, technology-driven interventions, offering a novel approach to managing pregnancy-related pain and paving the way for improved maternal care.
Railway Bridge Design Analysis With Deck Bulb Tee WF98DG Type Bearer Using Bridgelink V.8.0.0.2
Authors: Efendi Aco , Safitri Novia
Published: February 2025

The railroad track is crucial for people to cross the train, especially on lines with quite high elevations where the railroad is not permitted to have particularly high gridlines on its tracks. In its literal sense, a bridge is a construction that connects two areas that are divided by a barrier, which can be man-made or natural, such as highways, irrigation canals, and railroads, or it can be a river, valley, strait, or sea. The researcher will model the bridge girder with Bridgelink software for tracks on public railways, using pre-stressed concrete material with the type of grinder is Deck Bulb Tee WF98DG with a bridge span of 30 m. Referring to the railway geometry planning parameters according to the Minister of Transportation regulation No. PM. 60 of 2012. From the results of this study it is known that with a bridge cross-section of 3.124 m wide according to the needs of the width of the cross-section of a one-lane railway, which is a minimum of 3 m with a span length of 30 m using a single axle load of 20 tons requires a girder cross-section type Deck Bulb Tee WF98DG with the number of straight strand recommendations from bridge link is 18 pieces and Harped Strand as many as 7 pieces using fc' 35.16 MPa.
Study on the design of the Remote Distance Recording Automation Tool for Regional Water Utility Companies (PDAM) Water Distribution Using WIFI
Authors: Ilmi Ulul , Muiz Pratama Abdul
Published: February 2025

Based on the research study on the design of the Remote Distance Recording Automation Tool for PDAM Water Distribution Using WIFI, several conclusions can be drawn. The PDAM water usage recording device, which uses the Water Flow YF-S201 sensor on a microcontroller installed in the PDAM water distribution flow, can accurately read the volume of water flowing through the sensor. Experiments showed that the sensor achieved an average accuracy of 98.9% for water volumes ranging from 1.5 liters to 15 liters. This demonstrates the sensor's high precision in measuring water flow.To build the hardware and software circuit, the ESP8266 WiFi module was used on the atmega328 microcontroller. The data sent to the server via the WiFi network worked  as expected as long as it was within the range of the access point. Testing was conducted with a maximum distance of 8 meters, as the WiFi access point device used in the experiment could only reach a maximum of 10 meters and operated at a frequency of 2.4 GHz. This shows that the system can function well within a certain range and supports efficient wireless data transfer.
TECNOLOGIAS LEVE-DURAS NA SAÚDE: UMA REVISÃO INTEGRATIVA SOBRE INOVAÇÃO NO CUIDADO MÉDICO
Authors: Schmidt Moura Claudia , Figueiredo Rocha Lucas Henrique , Nunes da Bruz Aliny , De Aguiar Alves Luana , Soares de Souza Mariany , Vieira Silva Ítalo Renan , Botelho Lessa Isadora Maria , Oliveira de Arruda Vitória Andressa , Borges Rodrigues Iany Eduarda , Da Rocha Teiche Leandra Vitória , Prestes Polliany Aparecida , Alves de Miranda Pinto Julia , Fernandes Pereira Helena Isaura , Andrade Vasconcelos Rosane Maria , Teshima de Alencar Rafael
Published: February 2025

Analisar o impacto das tecnologias leve-duras na prática médica e na inovação dos processos de saúde. Revisão integrativa conduzida nas bases de dados LILACS, MEDLINE e SciElo, entre 2015 e 2024, utilizando descritores padronizados e estratégias booleanas. Foram selecionados oito artigos que destacaram a importância das tecnologias leve-duras na promoção de segurança, eficiência e humanização. Apesar das limitações, como a falta de capacitação e desafios estruturais, os resultados reforçam a relevância dessas tecnologias para integrar saberes técnicos e subjetivos, promovendo cuidado mais efetivo. Conclui-se que as tecnologias leve-duras são ferramentas indispensáveis para a melhoria dos processos na área da saúde.
Investigation on the density of negative deuterium ion in ECR plasma by optical emission spectroscopy
Authors: Yue Chen  , Xiaodong Zhu  ,   School of Physical Sciences, University of Science and Technology of China, Hefei 230026, China
Published: February 2025

The electron cyclotron resonance (ECR) plasma is characterized by low working pressure and high dissociation rate, which has important applications in the deuterium negative ion D- source technology. In this paper, the Yacora collisional-radiative model is applied to the emission spectrum diagnosis of D- in ECR deuterium plasma. The D- density is estimated by using the Dα/Dβ ratio and the relative intensity of other deuterium molecular lines, which avoids complex calibration procedure of absolute intensity. The spatial structure of D- are studied by the multichannel emission spectroscopy measurements in the source and diffusion regions.
The experiments are conducted on a 2.45 GHz ECR plasma source with a deuterium gas pressure of 1 Pa and microwave power of 660 W. The Balmer series of atomic deuterium (Dα, Dβ, Dγ, Dδ) and the Fulcher band Q-branches of molecular deuterium are measured at the source region and expanding region of the ECR plasma. It is found that the intensity of Dα in the source region is much higher than that of Dβ, and the Dα/Dβ ratio is as high as 23, indicating a selective enhancement of Balmer lines due to the mutual neutralization process of D-. Furthermore, D- density in the source region is estimated to be about 3.6×1015m-3, and the D- density in the expanding region decreases significantly. In ECR plasma source region, the plasma-wall interaction is strong due to the small volume of the cavity. The recombination desorption process produces more vibrationally excited molecules, which further enhances the dissociation attachment reaction and is beneficial to the generation of deuterium negative ions. On the other hand, the axial electric field within the ECR plasma inhibits the axial transport of D-, suggesting that the production and loss of D- is localized. These characteristics of the ECR plasma source contribute to a large gradient of D- density between the source and expanding region.
Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium
Authors: Medina-Feliciano Joshua G , Valentín-Tirado Griselle , Luna-Martínez Kiara , Beltran-Rivera Alejandra , Miranda-Negrón Yamil , García-Arrarás José E
Published: February 2025

In holothurians, the regenerative process following evisceration involves the development of a “rudiment” or “anlage” at the injured end of the mesentery. This regenerating anlage plays a pivotal role in the formation of a new intestine. Despite its significance, our understanding of the molecular characteristics inherent to the constituent cells of this structure has remained limited. To address this gap, we employed state-of-the-art scRNA-seq and HCR-FISH analyses to discern the distinct cellular populations associated with the regeneration anlage. Through this approach, we successfully identified thirteen distinct cell clusters. Among these, two clusters exhibit characteristics consistent with putative mesenchymal cells, while another four show features akin to coelomocyte cell populations. The remaining seven cell clusters collectively form a large group encompassing the coelomic epithelium of the regenerating anlage and mesentery. Within this large group of clusters, we recognized previously documented cell populations such as muscle precursors, neuroepithelial cells and actively proliferating cells. Strikingly, our analysis provides data for identifying at least four other cellular populations that we define as the precursor cells of the growing anlage. Consequently, our findings strengthen the hypothesis that the coelomic epithelium of the anlage is a pluripotent tissue that gives rise to diverse cell types of the regenerating intestinal organ. Moreover, our results provide the initial view into the transcriptomic analysis of cell populations responsible for the amazing regenerative capabilities of echinoderms.
The effect of an internet of things-based mobile health management application for older adults depending on user engagement in South Korea: a secondary analysis of a quasi-experimental study
Authors: Choi Jeongeun , Cho Hyeonmi , Seok Jo Woon , Lee Hyangkyu
Published: February 2025

Purpose: This study aimed to evaluate the effect of the TouchCare system, a digital health management system utilizing the internet of things (IoT), based on the usage levels of older adults. Methods: This is a secondary analysis of data from a quasi-experimental study examining the effects of an IoT-based digital healthcare system. Participants were equipped with the TouchCare application, a touch-tag, and context-aware artificial intelligence. Data on cognitive function, frailty, depressive symptoms, nutritional status, and fall efficacy were collected at baseline and after six months of using the system. The participants were divided into a high-engagement group (n = 22) and a low-engagement group (n = 24) based on how many days they used the application during the study. We used descriptive statistics, the paired t-test, the independent-samples t-test, and two-way mixed analysis of variance. Results: In total, 46 participants completed the evaluations (mean age, 76.6 years). Two-way mixed analysis of variance revealed no significant group-by-time interaction for cognitive function (p = .184), frailty (p = .338), depressive symptoms (p = .543), and nutritional status (p = .589). There was no significant difference in fall efficacy between the two groups (p = .091). The high-engagement group exhibited significant improvements in visuospatial and executive functions on the Montreal Cognitive Assessment (p = .029). Conclusion: The IoT-based mobile health management application demonstrated benefits in improving cognitive health among older adults. The findings suggest that active engagement with healthcare technology can positively affect health in this population, emphasizing the need for continuous support from nurses as health providers.
Evaluating machine learning models for predictive accuracy in cryptocurrency price forecasting
Authors: Qureshi Shavez Mushtaq , Saeed Atif , Ahmad Farooq , Khattak Asad Rehman , Almotiri Sultan H. , Al Ghamdi Mohammed A. , Shah Rukh Muhammad
Published: February 2025

Our research investigates the predictive performance and robustness of machine learning classification models and technical indicators for algorithmic trading in the volatile cryptocurrency market. The main aim is to identify reliable approaches for informed decision-making and profitable strategy development. With the increasing global adoption of cryptocurrency, robust trading models are essential for navigating its unique challenges and seizing investment opportunities. This study contributes to the field by offering a novel comparison of models, including logistic regression, random forest, and gradient boosting, under different data configurations and resampling techniques to address class imbalance. Historical data from cryptocurrency exchanges and data aggregators is collected, preprocessed, and used to train and evaluate these models. The impact of class imbalance, resampling techniques, and hyperparameter tuning on model performance is investigated. By analyzing historical cryptocurrency data, the methodology emphasizes hyperparameter tuning and backtesting, ensuring realistic model assessment. Results highlight the importance of addressing class imbalance and identify consistently outperforming models such as random forest, XGBoost, and gradient boosting. Our findings demonstrate that these models outperform others, indicating promising avenues for future research, particularly in sentiment analysis, reinforcement learning, and deep learning. This study provides valuable guidance for navigating the complex landscape of algorithmic trading in cryptocurrencies. By leveraging the findings and recommendations presented, practitioners can develop more robust and profitable trading strategies tailored to the unique characteristics of this emerging market.
The optimal training intervention for improving the change of direction performance of adolescent team-sport athletes: a systematic review and network meta-analysis
Authors: Chen Yonghui , Tulhongjiang Maiwulanjiang , Ling Tianpeng , Feng Xinmiao , Mi Jing , Liu Ruidong
Published: February 2025

Background

Due to the influence of growth, adolescent team-sport athletes have the need to improve their change of direction (COD) performance and reduce the risk of anterior cruciate ligament (ACL) injuries during COD. However, the optimal intervention for improving COD performance has not yet been determined.

Objective

To quantitatively assess the effects of diverse training interventions on COD performance.

Methods

A systematic search of five databases was conducted, adhering to the PRISMA guidelines. Randomized controlled trials that examined 10 distinct training interventions for COD performance in adolescent team-sport athletes were emphasized. Effect sizes were represented as standardized mean differences (SMD) with 95% credible intervals (CI). The Cochrane study risk assessment tool evaluated the risk of bias in the selected studies.

Results

Of the 36 studies analyzed, involving 1,125 participants. Eccentric overload training (EOT) (SMD = −2.06, 95% CI [−2.83 to −1.29]) emerged as the most effective training method for overall COD performance. Subgroup analysis shows that combined training (COM) (SMD = −2.14, 95% CI [−3.54 to −0.74]) was the best training intervention for COD performance with angles less than 90°. EOT (SMD = −2.84, 95% CI [−4.62 to −1.07]) also was two best training intervention for COD performance with angles greater than 90°.

Conclusions

The choice of training intervention should be determined based on the COD angle. When the COD angle exceeds 90° or is not restricted, EOT is the optimal intervention; however, this is not the case for angles below 90°. Further high-quality studies are needed in the future to validate these findings. Systematic review registration: PROSPERO CRD42024501819.
Sustainable Intensification in Agriculture: A Review of Focus Areas, Approaches, and Constraints
Authors: Amritha K. S. , Sreedaya G. S. , Shalini J. R.
Published: February 2025

The necessity to feed a growing population, coupled with the limited availability of arable land and the need to preserve natural resources, raises the need for Sustainable Intensification (SI) in agriculture. Over the past two decades, the use of SI in research and policy has grown significantly in response to these challenges.SI consists of a wide range of practices and this study reviews Sustainable Intensification (SI) in Agriculture by analysing a previously developed conceptual framework that identifies four key focus areas: land use, structural optimization, farm-level strategies, and regional approaches. To clearly understand the concept and to identify potential development paths, SI needs research combining several academic disciplines, such as agricultural science, ecology, economics, and rural studies. This review evaluates different farming systems contributing to SI, such as mixed crop-livestock systems, organic farming, conservation agriculture, climate-smart agriculture, smart farming, and the System of Rice Intensification. Additionally, the review explores SI from multiple disciplinary perspectives, examining its application from plant and field levels to landscape, regional, and global scales. It highlights SI’s benefits in boosting productivity, resilience, and resource efficiency while addressing environmental concerns. However, challenges such as unclear theoretical foundations, economic and institutional barriers, and criticisms of SI’s true impact remain. To overcome these, the review emphasizes the need for integrated food system strategies, improved infrastructure, and stronger policies. Future research should address theoretical gaps and promote inclusive, context-specific SI approaches. This paper is an umbrella review that seeks to define SI by examining its concept, key contributors, influencing factors, constraints and priority research areas.
Ca2+‐triggered membrane permeability transition in deenergized mitochondria from rat liver
Authors: Chernyak B.V. , Dedov V.N. , Chernyak V.Ya.
Published: July 2002

The opening of the cyclosporin A‐sensitive permeability transition pore (MTP) in deenergized mitochondria was induced only at millimolar Ca2+. Pretreatment of the mitochondria with ‘inducers’, such as duroquinone and phenylarsine oxide, allowed observing the pore opening at 0.01–0.1 mM Ca2+. Duroquinone caused a rapid (within 20 s) NAD(P)H oxidation which was followed by a slow (20 min) induction of the pore sensitive to low Ca2+. Phenylarsine oxide capable of cross‐linking of vicinal SH‐groups caused pore formation without the oxidation of NAD(P)H. The pore opening by both ‘inducers’ was prevented by N‐ethylmaleimide. We propose that oxidation or cross‐linking of critical dithiol(s) in membrane proteins increase the sensitivity of a putative ‘Ca2+‐sensor’ that regulates the permeability transition pore opening.
Preliminary microwave irradiation of water solutions changes their channel‐modifying activity
Authors: Fesenko E.E. , Geletyuk V.I. , Kazachenko V.N. , Chemeris N.K.
Published: July 2002

Earlier we have shown that millimetre microwaves (42.25 GHz) of non‐thermal power, upon direct admittance into an experiment bath, greatly influence activation characteristics of single Ca2+‐dependent K+ channels (in particular, the channel open state probability, P
o). Here we present new data showing that similar changes in P
o arise due to the substitution of a control bath solution for a preliminary microwave irradiated one of the same composition (100 mmol/1 KCl with Ca2+ added), with irradiation time being 20–30 min. Therefore, due to the exposure to the field the solution acquires some new properties that are important for the channel activity. The irradiation terminated, the solution retains a new state for at least 10–20 min (solution memory). The data suggest that the effects of the field on the channels are mediated, at least partially, by changes in the solution properties.
Magnesium sulfate as an anticonvulsant in eclampsia
Authors: Raman N. Venkat , Rao C. Anita
Published: July 2002

Objective: To examine the efficacy of magnesium sulfate (MgSO4) as an anticonvulsant in eclampsia and imminent eclampsia. Methods: Case records of 562 consecutive patients with eclampsia and 174 with imminent eclampsia treated at the Institute of Obstetrics and Gynaecology, Hyderabad, India, during the 3‐year period from January 1987 to December 1989, were reviewed. Management consisted of: (1) MgSO4 to control convulsions; (2) sublingual nifedipine to control hypertension; and (3) delivery of the fetus. Results: Convulsions were controlled in 95% of cases with the initial dose of magnesium and within half an hour in a further 2%. Cesarean section was performed mainly for obstetric indications. Depression of knee jerks was found to be the first sign of impending magnesium toxicity and with the precautions observed, magnesium toxicity was negligible. Maternal mortality was 2.4% (18 maternal deaths) and perinatal mortality 36% (247 perinatal deaths). Sixteen women with eclampsia (2.8%) and two with imminent eclampsia (1.1%) died. Of the 247 perinatal deaths, 61 were in the category of imminent eclampsia. There were 10 sets of twins. Cerebrovascular accident was the leading cause of maternal death. Fetal deaths and prematurity were important causes of perinatal loss. Conclusions: The control of convulsions is the most important aspect in the management of eclampsia, and MgSO4 is a very effective anticonvulsant.
Prognostic factors in endometrial cancer
Authors: Ludwig H.
Published: July 2002

Objective:

Most patients with endometrial carcinoma present with stage I disease and it is this group of patients in which prognostic factors have been studied, so that therapy can be tailored to the risks for recurrence. The papillary serous endometrial cancer and clear cell cancers have a poor prognosis but these comprise only a small proportion of endometrial cancer patients. The current surgical staging system for endometrial cancer is based on previously identified intra and extra‐uterine factors that influence the prognosis. However, much of the information regarding prognosis, such as histologic type and grade, evidence of disease beyond the uterus and receptor‐status can be gleaned from careful preoperative assessment of these patients. Information regarding ploidy and receptor status is available from curettage specimens and, with increasing use of hysteroscopy and/or vaginal ultrasound a more precise assessment of the extent of the disease in the uterine cavity and involvement of the cervix may be possible, although the uterine extent of the disease does not play the prognostic role that was anticipated formerly. A major concern regarding surgical staging has been the fact that many of these patients are elderly and obese with significant medical problems. There is the imminent risk that the pelvic and para‐aortic node dissection (rather than sampling) may increase morbidity. More studies have shown that this might not be a factor with sampling. But does it suffice? Similarly, concerns have been expressed regarding those patients who may require postoperative radiation which may be compromised by postoperative adhesions, bladder, intestine and ureteral problems. It is yet to be demonstrated that in diseases extending outside the pelvis, the currently available treatment affects survival. Undoubtedly, recurrence patterns will be affected but clear demonstration of survival advantage is not available, eventually will never be. The concepts of treatment of advanced disease with spread outside the pelvis should undergo rethinking in the way that control of the existing disease rather than eradicating it by all means might offer better chances for life quality, life expectancy albeit limited, in cancer patients.