bluuebunny/crossref_metadata_2025 huggingface dataset:
THE AEGEAN PROBLEM IN RELATIONS BETWEEN TÜRKIYE AND GREECE
Authors:   Baku Slavic University, Azerbaijan, Aliyeva Vusala
Published: January 2025

Throughout history, Greece and Türkiye have had a complex relationship characterized by both friendly relations and periods of conflict and confrontation. In the 20th century, there were several instances of war and conflict between the two nations. However, beginning in 1999, the two countries entered a new phase in their relations, characterized by increased cooperation and dialogue. This period was marked by the improvement of official relations between the governments of Greece and Türkiye, facilitated by the Greek government’s support for Türkiye’s efforts to join the European Union. Nevertheless, certain issues remain unresolved.

One of these disputes relates to the delineation of the territorial sea in the Aegean Sea. The issue in the Aegean arises from disagreements over the continental shelf and territorial waters. It should be noted that resolving this dispute is a matter of keen interest not only for Greece and Türkiye, but also for European countries, Russia, and Israel. The discovery of new oil and gas reserves in the Eastern Mediterranean has further complicated the issue. If the dispute is settled in favor of Türkiye, then these areas will belong to Southern Cyprus' territorial waters if it is settled in favor of both Türkiye and Greece. This factor directly affects Europe's dependence on Russian energy. Therefore, in proposing a resolution to the dispute, it is necessary to conduct legal and political analyses.

In general, there has been progress between Türkiye and Greece in terms of diplomatic, political, trade, economic, transportation, tourism, cultural, and educational relations. In order to resolve existing issues between the two countries, various mechanisms have been put in place through dialogue, including political discussions, meetings, and the High-Level Cooperation Council. Recently, the number of official high-level visits has increased. The High-Level Cooperation Council meetings take place alternately in Türkiye and Greece, coordinated by the heads of government and foreign ministers from both countries.

It can be concluded that the most appropriate course of action would be to grant these islands 3 nautical miles of territorial waters, in accordance with the provisions of the Lausanne Treaty of 1923 and the Paris Treaty of 1947. Considering the unchanged positions of both parties, it is advisable to resolve the matter of the delineation of territorial waters in the Aegean Sea in accordance with these principles and methods, in order to avoid this situation escalating into a global crisis.
Digital Twins in IT Systems: Applications and Challenges in Real-time System Monitoring
Authors: Kambala Gireesh
Published: January 2025

Digital twins, defined as virtual replicas of physical entities, are emerging as transformative tools in IT systems, bridging the gap between physical infrastructure and digital insights. This paper delves into their critical applications in real-time system monitoring, emphasizing their role in optimizing performance, enabling predictive maintenance, and enhancing cybersecurity. By creating dynamic models that simulate system behaviors and operational states, digital twins empower IT managers to make informed decisions with unparalleled precision.
The paper outlines key applications, including real-time performance monitoring, where digital twins analyze live data to optimize IT infrastructure efficiency. Predictive maintenance applications are explored, demonstrating how twins preemptively identify potential failures, reducing downtime and operational costs. Additionally, their utility in cybersecurity is highlighted, where digital twins detect and mitigate anomalies, safeguarding critical systems against cyber threats.
However, the integration of digital twins into IT systems is not without challenges. These include the complexities of managing vast amounts of real-time data, ensuring scalability across diverse IT environments, and addressing compatibility issues with legacy systems. Furthermore, real-time processing demands and concerns over data security and privacy are significant barriers to widespread adoption.
To address these challenges, the paper proposes solutions such as leveraging edge computing and AI for low-latency analytics, adopting standardized frameworks to enhance interoperability, and implementing advanced cybersecurity measures to protect sensitive data. Current best practices in deploying digital twins are also discussed, providing actionable insights for IT professionals.
The paper concludes by exploring future research directions, including hybrid digital twins, advancements in data synchronization, and cross-domain applications in sectors like healthcare and manufacturing. Ethical and governance considerations for large-scale digital twin adoption are also addressed, ensuring sustainable and responsible use of this technology.
This research underscores the transformative potential of digital twins in real-time system monitoring while providing a roadmap to navigate current barriers and unlock future opportunities. Through the comprehensive analysis presented, this paper aims to contribute to the evolving discourse on digital twin technology, fostering its integration into modern IT ecosystems.
Caminhando na cidade-corpo em busca de outras geo-grafias urbanas
Authors: Pequeno Victor Dantas Siqueira , Pereira Ana Paula Camilo
Published: January 2025

Nosso objetivo com o presente artigo consistiu em argumentar a favor dos elementos que garantem ao grafite e a pichação um teor geográfico na medida em que suas formas gráficas, estéticas, simbólicas e discursivas constituem um tipo paisagem-grafite que se quer militante e transgressora. Para tanto, mobilizamos o conceito de corpografia urbana proposto por Paola Jacques em interlocução com a noção de corpo-espaço inspirada nos pressupostos da Nova Geografia Cultural. Metodologicamente, trata-se de um trabalho de caráter qualitativo-exploratório. Em termos de resultados empíricos, apresentamos alguns registros fotográficos que representam as geografias inscritas nos muros grafados que compõem as paisagens urbanas de/em Santa Maria (RS).
El camino del Perro Andaluz: David Lynch, heredero del surrealismo
Authors: Magallanes Sophia , Galindo Lucía , Padilla Claudia , Rosales Aldo
Published: January 2025

: A 30 años de la muerte del recordado director español Luis Buñuel, David Lynch toma la posta y hereda la maestría del surrealismo buñueliano como forma de expresión. Lynch ha demostrado ser uno de los directores surrealistas más importantes, lo cual demuestra que el legado de Buñuel no se ha perdido ni se ha olvidado, sino que ha tomado nueva forma a través de este director.
Géneros en construcción: cine peruano, la restauración permanente
Authors: Felipe Ángela , Gordillo Sebastián , Hernández Annette , Poirier Josephine , Salazar Carmen
Published: January 2025

El cine peruano tiene una historia y una tradición que es corta e interrumpida por diversos sucesos que lo han afectado directamente. La dictadura del general Velasco Alvarado, el terrorismo y otros hechos importantes cambiaron la sociedad y le dieron un giro de 360 grados a nuestra incipiente industria cinematográfica. En los siguientes párrafos se intentará sustentar por qué en el Perú no existe el cine de género, aunque se encuentra en construcción.
Dossier: Luis Buñuel (España, 1900-1983)
Authors: Pita César , Martínez Juan Carlos
Published: January 2025

Del surrealismo puro a la edad de oro del cine mexicano, de vuelta a la madre patria y con broche de oro durante el autoexilio en Francia, la obra de Luis Buñuel es delirante, simbólica, perversa, cruel, misógina, hereje, nihilista, políticamente incorrecta y merecedora de la excomunion. Como un navajazo en pleno ojo. Nos quedamos cortos en méritos.
A demonização das imagens do outro
Authors: Sardelich Maria Emilia , Santos Ingrid Ferreira dos
Published: January 2025

Este artigo apresenta uma reflexão sobre gestos de insurgência praticados contra produções artísticas em cidades brasileiras no século XXI e, mais especificamente, contra o mural Do Orun ao Aiye: Afrika Elementar, produzido por Nathê Ferreira, Adelson Boris e Emerson Crazy, na cidade do Recife em 2021.  A partir de uma revisão bibliográfica, explora os quereres das imagens e possíveis gestos insurgentes contra elas. Conclui que o gesto insurgente de demonização contra o mural analisado não sinaliza apenas uma motivação religiosa, mas revela a persistência de um regime racializado de representação e estereotipagem contra as populações negras, que pode colocar em risco a integridade do patrimônio artístico das cidades brasileiras.
Mulheres em luta
Authors: Leite Marcelo Henrique , Meneguello Cristina
Published: January 2025

Partindo de um estudo de caso específico, o da estátua de María Remedios del Valle, inaugurada em novembro de 2022 na cidade de Buenos Aires, na Argentina, e totalmente destruída em setembro de 2023, este artigo propõe uma reflexão a respeito de estátuas como indícios das culturas históricas que as criaram, tecendo as relações entre monumentos e memória social. Dentro do contexto recente, a significância urbana e social das estátuas voltou a estar sob disputa – seja nos ataques a estátuas dentro do movimento mais amplo de “derrubada de estátuas” (urban fallism), seja na conquista da eternização de figuras antes subalternizadas. No caso específico de estátuas que retratam mulheres, a inflexão de gênero e, em muitos casos, de raça - indica reivindicações de visibilidade e, ao mesmo tempo, heroicização de algumas figuras em detrimento de outras.
Protocolo de abordagem da trombocitopenia imune no adulto
Authors: Anselmo Jose Lucas Tavares , Lopes Germison Silva , Galdino Gabriela Studart
Published: January 2025

O presente trabalho propõe um protocolo de abordagem clínica da trombocitopenia imune (TI), tendo em vista situar-se entre as principais causas de trombocitopenia do adulto, possuir uma vasta gama de diagnósticos diferenciais, além de poder se apresentar desde quadros assintomáticos até sangramentos graves ameaçadores à vida, tornando a condução clínica dessa doença um verdadeiro desafio. Para isso, foi realizada uma revisão de literatura utilizando diretrizes clínicas e artigos de revisão atualizados sobre o tema a fim de identificar as principais formas de apresentação clínica, os diagnósticos diferenciais mais relevantes, os exames complementares mais indicados, as principais indicações de tratamento, assim como os esquemas terapêuticos com maior evidência de resposta clínica. Com base nas evidências levantadas, foram elaborados fluxogramas contemplando recomendações objetivas referentes à abordagem diagnóstica e terapêutica direcionadas para as apresentações clínicas mais frequentes. Portanto, essa proposta de protocolo de abordagem da TI também se encontra sob análise para indexação aos protocolos institucionais do Hospital Universitário Walter Cantídio (HUWC), tendo em vista a importância da avaliação sistematizada na investigação do paciente com suspeita de TI, fornecendo mais segurança para assistência, com plano de tratamento direcionado de forma clara e adaptado à realidade dos profissionais médicos.
Pertahanan Budaya pada Upacara Sadranan di Dukuh Karang Duwur Banjarsari Wetan Kecamatan Sumbang Kabupaten Banyumas: Kajian Etnolinguistik
Authors: Marhamah Siti , Ramadhani Davina
Published: January 2025

Kebudayaan yang di miliki Indonesia sangat beragam salah satunya adalah kebudayaan yang ada di masyarakat Jawa yaitu Upacara Sadranan sebagai ritus yang masih banyak dilestarikan Penelitian ini bertujuan mengetahui siapa peserta dan penggerak kegiatan,bagaimana prosesi, uborampe dan nilai yang terkandung dalam upacara Sadranan di Dukuh Karang Duwur Desa Banjarsari Wetan, Kecamatan Sumbang. Upacara Sadranan Sadranan di Dukuh Karang Duwur Desa Banjarsari Wetan Kecamatan Sumbang Kabupaten Banyumas merupakan Upacara keagamaan yang dilaksanakan secara turun-temurun dari nenek moyang pada minggu ketiga atau keempat bulan Sya`ban dalam kalender hijriah. Upacara Sadranan juga menunjukkan keharmonisan masyarakat dengan alam semesta serta mengajarkan kepada generasi muda betapa berharganya upacara Sadranan bagi masyarakat. Mengembangkan program edukasi dan pemasaran yang lebih komprehensif akan membantu masyarakat lebih memahami dan menghayati nilai-nilai yang terkandung dalam upacara Sadranan. Upacara ini memberikan dampak dan nilai-nilai yang posistif bagi masyarakat Dukuh Karang Duwur dan sekitarnya. Upacara ini menjadi daya tarik peneliti karena di era yang serba maju, antusias Masyarakat masih sangat besar untuk mempertahankan dan melestarikan budaya yang diturunkan dari nenek moyang melalui bahasa yang terkandung dalam setiap prosesi dan uborampe serta nilai yang terkandung didalamnya.
IDENTIFIKASI DIATOMS PADA ORGAN HATI, GINJAL DAN PARU KORBAN TENGGELAM MENGGUNAKAN TIKUS PUTIH (Rattus norvegicus) DI SUNGAI PELUS SOKARAJA
Authors: PERAMIARTI IDSAP
Published: January 2025

Tenggelam adalah salah satu penyebab utama kematian ketiga di dunia. Kematian akibat tenggelam yang terjadi di air tawar (sungai, danau, kolam) hampir 90%. Salah satu pemeriksaan khusus untuk mengidentifikasi korban yang meninggal akibat tenggelam adalah dengan pemeriksaan diatom. Diatom adalah fitoplankton uniseluler yang dapat digunakan sebagai bukti intravitalitas korban tenggelam, artinya korban masuk ke dalam air saat masih hidup dan kemudian mati. Penelitian ini bertujuan untuk mengetahui diatom pada organ hepar, ginjal dan paru-paru tikus putih yang tenggelam di Sungai Pelus. Penelitian ini menggunakan metode eksperimen, dengan 15 ekor tikus putih (Rattus norvegicus) yang ditenggelamkan di air Sungai Pelus. Identifikasi diatom pada hepar, ginjal dan paru dilakukan dengan metode destruksi asam. Hasil yang diperoleh di hati teridentifikasi 19 diatom dari 7 genera : Amphora, Eunotia, Simonsenia, Epithemia, Fragilaria, Ulnaria, dan Synedra; organ ginjal mengidentifikasi 22 diatom dari 7 genera : Amphora, Navicula, Cymbella, Cocconeis, Epithemia, Fragilaria, dan Ulnaria; dan organ paru-paru teridentifikasi sebanyak 94 diatom dari 10 genera : Amphora, Diadesmis, Navicula, Simonsenia, Nitzschia, Epithemia, Isthmia, Ulnaria, Synedra, dan Aulacoseira. Sedangkan dari hasil pemeriksaan sampel air media Sungai Pelus didapatkan 14 genus diatom yaitu Amphora, Eunotia, Diadesmis, Navicula, Simonsenia, Nitzschia, Cymbella, Cocconeis, Epithemia, Isthmia, Fragilaria, Ulnaria, Synedra, dan Aulacoseira. Dari penelitian ini dapat disimpulkan bahwa genus diatom yang ditemukan di hati, ginjal dan paru-paru sama dengan genus yang ditemukan pada sampel air medium Sungai Pelus.
PERANAN DOKTER FORENSIK DAN DOKTER UNIT GAWAT DARURAT DALAM PENANGANAN KASUS TINDAK PIDANA PERDAGANGAN ORANG (TTPO)
Authors: Fitrianti Mia Yulia
Published: January 2025

Peningkatan kasus tindak pidana perdagangan orang merupakan fenomena gunung es karena sebenarnya banyak korban melapor dengan pidana lain, diperlukan kejelian dokter dalam anamnesa menggunakan pendekatan berdasarkan kebutuhan korban, korban ternyata merupakan korban tindak pidana perdagangan orang (TTPO). Selain itu banyak korban perdagangan orang datang meminta pertolongan medis khas korban TTPO tetapi tidak disadari oleh dokter, seperti pada kulit, dan bagian tubuh lainnya adanya luka bekas sayatan, luka bakar, infeksi menular seksual. Diperlukan pemeriksaan secara komprehensif untuk memberikan bukti objektif pasien yang datang merupakan korban perdagangan manusia. Ketidak pekaan pemberi layanan akan makin membuat korban tidak percaya dengan tenaga kesehatan bahkan penegak hukum. Penelitian ini membahas pentingnya peranan dokter forensik dan dokter UGD dalam penanganan awal atau screning korban TTPO yang sering datang bukan sebagai korban TTPO berdasarkan kebutuhan korban. Metode penelitian yang digunakan penelitian normatif empiris dengan pendekatan live case study, bersifat deskriptif. Hasil penelitian peranan dokter unit gawat darurat dan dokter forensik sangat penting dalam screening awal korban TTPO sehingga diperlukan pemahaman dan pengetahuan yang sama serta selaras dalam pelayanan tersebut guna membantu korban mendapatkan hak terutama hak atas kesehatan dan restitusi. Metode penelitian menggunakan metode penelitian yuridis normatif. Hasil penelitian mengidentifikasi korban TTPO masih menjadi tantangan bagi dokter forensik, penegak hukum dan pemerintah. Kolaborasi antara pemberi layanan kesehatan (dokter spesialis forensik) dapat membantu mengungkapkan unsur-unsur dalam TTPO dalam bentuk Visum et Repertum. Selain itu Visum et Repertum merupakan suatu hal yang penting dalam pembuktian karena menggantikan sepenuhnya corpus delicti (tanda bukti).
SCOOPING REVIEW: KEMATIAN KARENA KRATOM
Authors: Djunet Nur Aini Aini Djunet
Published: January 2025

Latar Belakang: Kratom adalah tanaman famili kopi yang tumbuh subur di Asia Tenggara. Daun kratom tinggi dengan alkaloid mitraginin yang bersifat stimulansia. Sampai saat ini kratom dilegalkan bahkan bernilai ekspor tinggi di Indonesia, berbeda dengan Malaysia dan Thailand yang telah melarang peredaran kratom. Beberapa studi melaporkan kasus toksisitas kratom namun data kematian terkait kratom masih terbatas.
Tujuan: Untuk mengetahui data kematian dengan riwayat penggunaan kratom.
Metode: Pencarian artikel yang terbit pada lima tahun terakhir secara sistematis pada tujuh database artikel. Berdasarkan skrining dan kriteria penelitian didapatkan empat laporan kasus.
Hasil: Seluruh kasus kematian karena kratom terjadi di Barat, tepatnya Kanada, Inggris, dan Amerika Serikat. Perbedaan sediaan kratom di Barat dengan Asia Tenggara tampaknya berhubungan dengan risiko kematian. Seluruh korban juga mengonsumsi antipsikotik dan senyawa psikoaktif sehingga terjadi supratherapeutic systemic concentration. Hasil otopsi penggunaan kratom dengan zat lain adalah aritmia, kardiomegali, kardiomiopati, aterosklerosis koroner, focal band necrosis pada miokardium, hipertensi, hipertrofi ventrikel kiri, dan miokarditis.
Simpulan: Risiko kematian karena kratom meningkat jika dikonsumsi bersama dengan antipsikotik dan senyawa psikoaktif. Kelainan system kardiovaskuler terkait takikardia dan hipertensi adalah yang paling sering ditemukan pada otopsi.
Pemberdayaan Kader Posyandu Untuk Gencarkan Imunisasi Wujudkan Desa Zero Kasus Penyakit yang Dapat Dicegah Dengan Imunisasi (PD3I)
Authors: Muntafiah Alfi , Inayati Nor Sri , Fadlilah Synta Haqqul , Oliviany Windy , Santosa Qodri
Published: January 2025

Imunisasi merupakan upaya pencegahan dan pemberantasan penyakit paling cost effective melalui pemberian kekebalan tubuh. Upaya ini perlu dilaksanakan kontinyu, menyeluruh, dan sesuai standar sehingga mampu memberikan perlindungan kesehatan dan memotong rantai penularan. Hasil penelitian melalui kuesioner dan wawancara terhadap kader di desa binaan didapatkan adanya hambatan kader dalam imunisasi di Posyandu diantaranya masalah acceptance publik mengenai imunisasi. Masih banyak ibu balita yang tidak mau anaknya diimunisasi karena berbagai alasan. Hal ini dikhawatirkan dapat menurunkan cakupan imunisasi dan memunculkan kerawanan KLB di masa mendatang. Keterbatasan pengetahuan dan keterampilan mengenai imunisasi juga dialami kader. Kegiatan ini dilakukan dengan sasaran kader Linggasari. Metode kegiatan: 1) Edukasi imunisasi; 2) Pelatihan skill konseling imunisasi. Hasil edukasi menunjukkan peningkatan signifikan hasil pre-post test, yang menjadi bukti bahwa kegiatan ini berhasil mencapai tujuan dalam meningkatkan pengetahuan kader. Melalui kegiatan pelatihan konseling, kader diharapkan dapat membantu masyarakat memahami manfaat imunisasi dan mengatasi kekhawatiran dan  keraguan masyarakat.
Penggalangan Komitmen Banyumas Dalam Mencegah Thalassemia Menuju Banyumas Goes To Zero Thalassemia 2030
Authors: Sulistyowati Erna Husein , Grehastuti Widyana , Faiza Dinar , Novia Dani Esti , Suprihatin Suprihatin , Purwoko Ari , Aminah Siti
Published: January 2025

Thalassemia merupakan penyakit genetik yang memerlukan perhatian serius di Kabupaten     Banyumas. Dengan jumlah penderita yang terus  meningkat, diperlukan upaya pencegahan yang   komprehensif dan berkelanjutan. Kegiatan sosialisasi ini bertujuan untuk menggalang komitmen seluruh pemangku kepentingan dalam  upaya pencegahan thalassemia di Banyumas.  Metode yang digunakan adalah sosialisasi   massal dengan mengundang 150 peserta dari  berbagai elemen masyarakat. Hasil kegiatan  menunjukkan antusiasme yang tinggi dari  peserta, tercermin dari diskusi interaktif  dan pertanyaan yang diajukan. Kegiatan ini  berhasil meningkatkan pemahaman dan kesadaran peserta tentang pentingnya pencegahan   thalassemia, serta menghasilkan komitmen  bersama untuk mendukung program "Banyumas   goes to Zero Thalassemia 2030". Kesimpulannya, sosialisasi ini merupakan langkah awal yang  penting dalam upaya pencegahan thalassemia di Banyumas, namun diperlukan tindak lanjut dan kerja sama yang berkelanjutan dari seluruh  pihak untuk mencapai tujuan yang diharapkan
Pemberdayaan Perempuan Dalam Pencegahan Kanker Serviks: Program Edukasi Untuk Anggota PKK Sokanegara Purwokerto Timur
Authors: Nafiisah Nafiisah , Gumilas Nur Signa Aini , Harini Ika Murti , Tamad Fatiha Sri Utami , Sutrisno Sutrisno , Ati Viva Ratih Bening
Published: January 2025

Kanker serviks, atau kanker leher rahim, merupakan salah satu penyebab utama kematian akibat kanker pada wanita. Tingginya angka kejadian kanker serviks berkaitan dengan kurangnya pengetahuan masyarakat. Pada 2022, deteksi dini pada wanita usia 30-50 tahun di Kabupaten Banyumas menunjukkan hasil positif IVA sebesar 2,1%, dengan 0,2% kasus dicurigai sebagai kanker serviks. Program ini bertujuan meningkatkan pemahaman anggota PKK RT 02 RW 11 Kelurahan Sokanegara tentang pencegahan kanker serviks melalui edukasi langsung, sosialisasi, diskusi, dan tanya jawab. Evaluasi dilakukan dengan pre-test dan post-test, menunjukkan peningkatan signifikan dalam pemahaman peserta mengenai pentingnya pencegahan kanker serviks, partisipasi dalam diskusi, serta niat untuk melakukan pemeriksaan rutin. Hasil pengamatan menunjukkan peningkatan kesadaran peserta tentang bahaya kanker serviks dan pentingnya pemeriksaan rutin.
HUBUNGAN KADAR TIMBAL, ARSEN, DAN AIR RAKSA DENGAN STATUS GIZI ANAK CEREBRAL PALSY DI KABUPATEN BANYUMAS
Authors: Widodo Azzahra Wuri , Laksana Agung Saprasetya Dwi , Kuncoro Prasetyo Tri
Published: January 2025

Latar Belakang Salah satu faktor risiko penyebab cerebral palsy adalah paparan logam berat. Timbal (Pb), arsen (As), dan air raksa (Hg) merupakan logam berat yang neurotoksik. Pb, Hg, dan As juga dapat mempengaruhi status gizi anak normal maupun anak cerebral palsy. Tujuan penelitian ini adalah untuk mengetahui hubungan kadar Pb, As, dan Hg dengan status gizi anak cerebral palsy di Kabupaten Banyumas. Metode Rancangan penelitian ini adalah cross-sectional. Sampel ditetapkan dengan non probability sampling menggunakan metode consecutive sampling. Pengumpulan data dilakukan dengan mengisi kuesioner data diri, mengukur tinggi dan berat badan, serta memotong rambut anak untuk dilakukan pemeriksaan kadar Pb, As dan Hg dengan spektrofotometer serapan atom (SSA). Data yang diperoleh dianalisis menggunakan uji Spearman. Hasil didapatkan sebanyak 24 anak cerebral palsy usia 1-12 tahun. Karakteristik data yang diperoleh berdasarkan jenis kelamin didapatkan mayoritas laki-laki (54,2%) dan berdasarkan usia paling banyak berusia 6-12 tahun (70,8%). Uji statistik menunjukkan kadar Pb (p = 0,716) tidak berhubungan dengan status gizi anak cerebral palsy di Kabupaten Banyumas. Hasil uji statistik kadar arsen (p = 0,681) tidak berhubungan dengan status gizi anak cerebral palsy di Kabupaten Banyumas. Uji statistik kadar air raksa (p = 0,453) menunjukkan tidak ada hubungan dengan status gizi anak cerebral palsy di Kabupaten Banyumas.
HUBUNGAN KADAR NATRIUM DAN KALIUM SERUM DENGAN TEKANAN DARAH DAN DENYUT NADI PADA PASIEN GAGAL JANTUNG
Authors: Asworo Fadhillah Noor Izza , Hediningsih Yekti , Marfuati Nanik
Published: January 2025

Heart failure is the inability of the heart to carry out its function, namely pumping blood at a normal frequency for tissue needs, which causes compensatory mechanisms, namely activation of the renin-angiotensin system, narrowing of the arteries and release of adrenergic. The renin-angiotensin system will increase renin which will then increase aldosterone, causing changes in serum sodium levels and serum potassium levels. Meanwhile, narrowing of the arteries due to decreased contractility will affect blood pressure, while adrenergic release will increase the pulse rate. This study aims to prove the relationship between serum sodium and potassium levels with blood pressure and pulse rate in heart failure patients. This research is a cross sectional study, with 23 patients as respondents. Samples were collected using the sequential sampling method. The data used are medical records that check serum sodium and potassium levels at one time with blood pressure and pulse. The results obtained showed that the average serum sodium level was 135.7 ± 6.643 mEq/L, the average serum potassium level was 4,087 ± 0.7485 mEq/L, the average systolic blood pressure was 123.35 ± 29.518 mmHg, the average mean diastolic blood pressure 70.43 ± 31,334 mmHg, mean pulse 99 ± 31,010 times per minute. The significance value of the Spearman Rank test on serum sodium levels with blood pressure was 0.910 (p>0.05), on sodium levels with pulse rate was 0.713 (p>0.05), on serum potassium levels with blood pressure was 0.076 (p> 0.05), and serum potassium level with pulse was 0.344 (p>0.05). It can be concluded that there is no significant relationship between serum sodium and potassium levels and blood pressure and pulse rate.
ISOLAT PROTEIN WHEY MENINGKATKAN SATIETY DAN MENGURANGI ASUPAN KALORI MELALUI INDUKSI SINYAL ANOREKSIGENIK
Authors: Wisesa Sindhu , Soraya Aristi Intan , Wahyudin Wahyudin
Published: January 2025

Restriksi kalori merupakan strategi yang efektif dalam menurunkan berat badan, tetapi sulit diimplementasikan pada individu overweight atau obesitas dengan masalah overeating. Kurangnya asupan kalori dan penurunan lemak tubuh meningkatkan sinyal lapar (hunger) pada hipotalamus, sehingga dapat memicu konsumsi makan yang berlebih. Asupan protein menunjukkan peningkatan satiety lebih baik daripada karbohidrat atau lemak, sehingga diet tinggi protein dapat menurunkan total asupan kalori. Isolat protein whey merupakan olahan susu dengan jumlah protein yang tinggi dengan harga yang relatif murah, berpotensi digunakan dalam manajemen penurunan berat badan karena dapat meningkatkan satiety. Review ini bertujuan untuk menelaah efektivitas dan mekanisme protein whey dalam meningkatkan satiety pada orang dewasa. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) digunakan dalam review. Kata kunci “whey”, “protein”, “isolate”, “satiety”, dan “adult” digunakan untuk mencari artikel pada database Pubmed dan ScienceDirect. Sebanyak tujuh studi hasil uji klinik ditemukan setelah skrining. Isolat protein whey meningkatkan satiety, menurunkan rasa lapar, dan mengurangi jumlah asupan makan lebih baik daripada karbohidrat atau placebo, terutama jika dikonsumsi bersamaan dengan makanan. Kadar serum adiponectin dan plasma glucagon-like peptide-1 (GLP-1) meningkat setelah konsumsi isolat protein whey. Tidak terdapat perbedaan satiety antara asupan isolat protein whey dengan asupan isolat protein kedelai, kacang polong, kentang, beras, β-lactoglobulin, α-lactalbumin, atau campuran asam amino. Isolat protein whey meningkatkan satiety dan menurunkan rasa lapar pada orang dewasa melalui peningkatan sinyal adiponectin dan GLP-1, sehingga menurunkan total asupan kalori dan berpotensi digunakan dalam manajemen penurunan berat badan.
KONSENTRASI EKSTRAK ETANOLIK DAUN PEPAYA (Carica papaya L.) TERHADAP PERUBAHAN WARNA BASIS GIGI TIRUAN RESIN AKRILIK POLIMERISASI PANAS
Authors: Purnama Ryana Budi , Laksitasari Anindita , Handayani Fani Tuti , Widyaningsih Pratiwi Nur , Rahmawati Dewi , Milla Dzhofirotul , Artanti Evania Bellinda , Nahya Bintan
Published: January 2025

Heat-cured acrylic resin is one of the materials used in making denture bases which has the disadvantage that it easily absorbs water and can make discoloration. Papaya leaves (C. papaya L) contain phenolic compounds (C6H6OH-) which can affect the color change of heat-cured acrylic resin. The purpose of this study is to determine the effect of various concentrations of papaya extract on discoloration of the heat-cured acrylic resin denture base. This experimental research is done in vitro at a laboratory using papaya leaf extract (C. papaya L) concentrations of 5%, 10%, and 20%. Thirty two samples of acrylic resin plates were divided into 4 groups, namely the immersion treatment group in papaya leaf extract concentrations of 5%, 10%, and 20%, and the negative control group in the form of aquadest soaking. The color change test was carried out using a UV-visible spectrophotometer. Data was analyzed using the One-Way ANOVA followed by Post-Hoc LSD test. The results of the study showed that there was a very significant difference in the mean value of color change between the treatment groups soaking in papaya leaf extract at concentrations of 10% and 20% and the control group, while at 5% concentration there was no significant difference from the control group. The lowest mean absorbance value was in the distilled water immersion group of 3.341350 ± 0.0942091 and the highest mean absorbance value was in the 20% immersion group of 3.553638 ± 0.0227829. This study concluded that there is an effect of various concentrations of papaya leaf extract on discoloration of the heat-cured acrylic resin denture base.
Keywords: Carica papaya L, discoloration, acrylic resin, denture base.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI PADA PASIEN PROLANIS LANSIA DI WILAYAH KERJA PUSKESMAS TAMBAK KABUPATEN BANYUMAS
Authors: Amalia Ary Nahdiyani , Fitriyani Novita Endang , Arfani Anun
Published: January 2025

Keluarga merupakan faktor yang memiliki dampak besar terhadap kepatuhan karena akan memotivasi penderita untuk lebih percaya diri ketika sedang mengatasi masalah kesehatan yang sedang dailami. Penelitian ini bertujuan untuk mengetahui hubungan dukungan yang diberikan oleh keluarga dengan kepatuhan pengobatan hipertensi pasien prolanis usia lanjut di Puskesmas Tambak 1 dan 2. Desain studi yang digunakan yaitu observasi secara analitik cross sectional . Penelitian dimulai pada bulan April-Mei 2023 di Puskesmas Tambak 1 dan 2 yang dilakukan pada 92 pasien. Pengumpulan data menggunakan kuesioner dan dilakukan pengujian Spearman rho . Hasil penelitian menunjukkan nilai p = 0,002 (p< 0,05), yang artinya terdapat hubungan yang signifikan antara dukungan keluarga dengan kepatuhan minum obat pasien prolanis lansia di Puskesmas Tambak 1 dan 2. Koefisien korelasi (r) yang diperoleh sebesar 0,321 dan arah hubungan yang diperoleh nilai r positif, artinya semakin keluarga mendukung penderita maka semakin tinggi derajat kepuasan berobat. Kesimpulan yang dapat diambil adalah kepatuhan pengobatan hipertensi berhubungan erat dengan dukungan yang diberikan oleh anggota keluarga pasien prolanis lansia di Puskesmas Tambak 1 dan 2. Pihak Puskesmas dapat memberikan informasi, edukasi, atau penyuluhan kesehatan kepada peserta prolanis hipertensi tentang pentingnya kepatuhan pengobatan hipertensi dan peran keluarga dalam memberikan dukungan untuk menjaga kestabilan tekanan darah pasien prolanis.
EKSTRAK TUMBUHAN SEBAGAI AGEN ANTIMIKROBA UNTUK METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA): REVIEW
Authors: Pauzi Rizqi Yanuar , Septiya Lia , Ihtiaringtyas Suci , Wahyudin Wahyudin
Published: January 2025

Ekstrak tumbuhan telah menjadi subjek penelitian menarik dalam pencarian agen antimikroba efektif terhadap Methicillin-Resistant Staphylococcus Aureus (MRSA), yang merupakan masalah kesehatan global karena resistensinya terhadap berbagai antibiotik. Beberapa penelitian menunjukkan bahwa senyawa-senyawa seperti alkaloid dan polifenol pada tumbuhan bertanggung jawab atas sifat antimikroba yang dimiliki oleh tumbuhan tersebut. Ekstrak dari tumbuhan seperti Azadirachta indica, Psidium guajava, dan Rhamnus californica telah menunjukkan aktivitas antibakteri terhadap MRSA. Penelitian lain menunjukkan senyawa seperti Psorothatin C dari Psorothamnus fremontii juga efektif melawan MRSA. Tantangan utama dalam pengelolaan infeksi MRSA adalah resistensi terhadap antibiotik konvensional seperti vancomycin. Oleh karena itu, penelitian lebih lanjut terhadap ekstrak tumbuhan dan senyawa sintetis yang memiliki aktivitas antimikroba terhadap MRSA dapat memberikan kontribusi penting dalam pengembangan terapi baru. Pendekatan yang melibatkan kombinasi ekstrak tumbuhan dengan antibiotik konvensional juga menunjukkan potensi meningkatkan efektivitas pengobatan. Pemahaman mendalam tentang mekanisme kerja ekstrak tumbuhan ini penting untuk mengembangkan strategi pengobatan yang efektif, dan dengan penelitian lebih lanjut, ekstrak tumbuhan dapat menjadi alternatif penting dalam mengatasi infeksi MRSA yang resisten terhadap antibiotik.
ANGIOSARCOMA PILORUS: LAPORAN KASUS
Authors: Ammar Faiq Muhammad , Khalik Arief Ismail
Published: January 2025

Angiosarcoma adalah satu jenis kanker jaringan lunak berasal dari sel endotel pembuluh darah yang jarang terjadi dan sangat agresif. Angiosarcoma memiliki prognosis yang buruk dengan tingkat harapan hidup yang rendah. Tidak ada manajemen standar yang dapat digunakan sebagai pedoman untuk pengobatannya sehingga menjadi tantangan bagi tim yang menangani. Laporan kasus ini bertujuan untuk menelaah lebih lanjut terkait manifestasi klinis, penegakan diagnosis, dan penanganan angiosarcoma pilorus. Kami melaporkan sebuah kasus seorang perempuan berusia 55 tahun dengan keluhan buang air besar berwarna hitam, disertai buang air besar keras dan sulit, nyeri perut sebelah kiri atas dan ulu hati yang terasa hingga ke punggung, perut terasa kembung, penurunan berat badan, dan nafsu makan. Pemeriksaan esofagogastroduodenoskopi menunjukkan adanya massa pada antrum gaster. CT Scan abdomen dengan kontras menunjukkan massa dengan centripetal filling enhancement yang menempel dan sulit dipisahkan dari struktur pilorus gaster. Laparotomi eksisi massa tumor dan reseksi pilorus, anastomose gaster duodenum dilakukan pada pasien tersebut. Pemeriksaan patologi anatomi memberikan hasil angiosarcoma.
SIW Directional Coupler with Improved Isolation for X-band Applications
Authors: Nguyen Thuy-Linh , Luong Duy Manh , Mai Ta Van , Nguyen Hoang Huy , Nguyen Hung Tuan , Kieu Phuong Khac , Tran Huong Thi Thu
Published: January 2025

This paper presents the design of a high-isolation directional coupler for X-band applications, utilizing substrate integrated waveguide (SIW) technology. The coupler features a simple structure, compact size, and ease of integration with other planar circuits. Typically, the S-parameters of a directional coupler are determined by the dimensions of the SIW and the aperture (or hole) of the coupler. In this study, we introduce additional via lines to modify the SIW and the coupler aperture, aiming to achieve high isolation. First, two via lines are embedded in the center, converging into two central vias that form the coupler's aperture. The power ratio within the coupler is controlled by adjusting the width of the aperture and the overall width of the SIW. Specifically, the width of the SIW at the aperture position is affected by adding vias on the two outer sides of the SIW. By incorporating these vias, we can effectively manage the power distribution across the four ports while ensuring sufficient isolation among them. The proposed design achieves an insertion loss of 3.3 dB, a coupling factor of 6 dB, and an isolation factor of 28.6 dB at 10 GHz. Experimental results demonstrate that the coupler maintains S_41 less than -20 dB over a 30% fractional bandwidth, ranging from 8.6 GHz to 11.6 GHz.
Degree and eccentricity based topological indices of some Benzophenone derivatives and their applications
Authors: Padmapriya Puttaswamy , Pooja Shivashankar , Gokul Rajeev Vidya , Sangamesha Madanahalli Ankanathappa , Venkataravanappa Lakshmi Ranganatha , Cangul Ismail Naci
Published: January 2025

Chemical graph theory is the application of discrete mathematics to chemistry applied to model, physical and biological properties of chemical compounds. Various topological indices which are derived from graph theory can model the geometric structure of chemical compounds. Several of these topological indices are used to construct boiling point models for alkanes with 1-12 carbon atoms. The models are used to predict the boiling points of a set of alkanes with 13-22 carbon atoms. Similarly, melting point models are considered for a family of alkanes having 10-20 carbon atoms and only one methyl group. Methyl-substituted alkanes such as these are especially important in the production of diesel and jet fuels since they enable a lower pour point for the resulting synthetic fuels. All models produced in this manner may be used to predict physical properties of compounds for which no experimental data exist. In this paper we found predicted melting point of benzophenone derivatives.
The effect of microwave radiation on egg and larval stages of the almond moth Cadra cautella (Walker) and the nutritional value of the dates
Authors: Abbood Naseer Malaky , Al-Yaqoubi Hussein Saleh , Albadry Majid A. Z.
Published: January 2025

The mortality rates of 24-hour eggs almond moth Cadra cautella were significantly affected by microwave radiation; the maximum mortality rates of 100% occurred at 15, 20, and 25 seconds exposure for the 600 watt power level, while the kill rate of 100% occurred for 48-hour eggs at 20 and 25 seconds exposure for the 600 watt power level. The incubation period of eggs was likewise impacted by microwaves. Microwaves affected the mortality rates of the almond moth larvae's first-instar, which reached 100% at 600 watt of power and exposure times of 15, 20, and 25 seconds at 400 watt of power and exposure times of 25 seconds. Radiation has a significant effect on the duration of the larval stage, wherein the duration of the larval stage increased with increasing exposure period to microwaves. The highest mortality rate for larvae in the fifth instar (96.67%) at power level 600 watt and period of exposure 25 seconds and significant differences with the treatment of control which amounted to 0%. The results demonstrated that the date components of protein and carbohydrates were not significantly impacted by the microwaves at the power levels and exposure times employed, all values were near to one another, and there was no significant difference from the control treatment.
Medical Digital Twins for Personalized Chronic Care
Authors: Papazoglou Michael P. , Krämer Bernd J. , Raheem Mira , Elgammal Amal
Published: January 2025

This work introduces the concept of Patient Medical Digital Twins (PMDTs) to simulate treatment outcomes, optimize drug dosages, and deliver personalized chronic care. The PMDT model, supported by an interconnected ecosystem, is validated iteratively by medical institutions to ensure its efficacy and applicability. At its core, the PMDT leverages expressive knowledge structures to capture a patient’s psychosomatic, cognitive, biometric, and genetic data, creating a comprehensive personal digital footprint. This enables medical professionals to run simulations predicting health issues over time and to proactively implement personalized preventive interventions. The PMDT ecosystem integrates big data analytics, continuous monitoring, cognitive simulation, and AI technologies. By connecting stakeholders across the care continuum, it provides deeper insights into a patient’s medical history and supports informed, shared decision-making. Validated in a pilot study through an EU-funded healthcare initiative, the PMDT demonstrates its transformative potential at the intersection of Big Data and AI, positioning itself as a critical tool for advancing personalized preventive care.
Affektive Polarisierung und ökonomisches Wählen
Authors:   , Stövsand Lars-Christopher
Published: January 2025

Diese Untersuchung widmet sich der Frage, ob affektive Polarisierung ökonomisches Wählen beeinflusst. Basierend auf einem theoretischen Erklärungsmodell, demgemäß affektive Polarisierung politisch motivierte Wahrnehmungsverzerrungen, politische Segmentierung sowie selektiven Medienkonsum begünstigt, wird davon ausgegangen, dass es hierdurch zu einer Abschwächung des ökonomischen Wählens kommt. Auf der Basis von Daten der CSES, des CMP, der Weltbank und des ParlGov-Projekts wird unter Nutzung mehrerer Mehrebenenregressionsmodellen analysiert, ob die individuelle und die gesellschaftliche affektive Polarisierung ökonomisches Wählen abschwächt, ob sie den Einfluss der tatsächlichen ökonomischen Performanz auf die Wahrnehmung der Wirtschaftsentwicklung verringert und ob sie den Zusammenhang zwischen der Wahrnehmung der Wirtschaftsentwicklung und der Wahlentscheidung mindert. Die Ergebnisse zeigen, dass ökonomisches Wählen insgesamt eher schwach ausgeprägt ist, dass es aber weder von der individuellen noch von der gesellschaftlichen affektiven Polarisierung beeinflusst wird. Außerdem erweisen sich die Wahrnehmungen der Wirtschaftsentwicklung als ein stark von politischen Präferenzen durchsetztes, unzuverlässiges Maß für ökonomisches Wählen, das bei hoher affektiver Polarisierung weiter an Nützlichkeit einbüßt.
Efficacy of different botanicals against gram pod borer, Helicoverpa armigera Hubner and pod fly, Melanagromyza obtusa Malloch in pigeonpea
Authors:   Agricultural Research Station, Anand Agricultural University, Derol- 389 320, Panchmahal, Gujarat, India, Hadiya G D , Damor C B ,   Agricultural Research Station, Anand Agricultural University, Derol- 389 320, Panchmahal, Gujarat, India, Patel M B ,   Agricultural Research Station, Anand Agricultural University, Derol- 389 320, Panchmahal, Gujarat, India
Published: January 2025

The efficacy of various botanicals against the gram pod borer, Helicoverpa armigera Hubner, and the pod fly, Melanagromyza obtusa Malloch, in pigeonpea was tested in a field experiment carried out during Kharif, 2018–19, 2019–20, and 2020–21 at the Agricultural Research Station, Anand Agricultural University, Derol, Gujarat, India. Determining the effectiveness of botanical extracts mainly some challanges affected such as botanical cost, application feasibility and farmer acceptance made complicated for pest management strategies in pigeonpea cultivation. The larval population of H. armigera was found to be considerably reduced in the plot treated with neem seed kernel extract at 5 percent and it was at par with azadirachtin at 0.15 EC @ 0.0006 percent and neem oil at 0.5 percent. A similar trend was also noted in terms of the percentage of harvested pod damage due to H. armigera; 5 percent of neem seed kernel extract had a significantly lower pod damage and was comparable to azadirachtin 0.15 EC 0.0006 percent. The lowest per cent grain damage due to pod fly, M. obtusa was noticed in a plot treated with azadirachtin 0.15 EC 0.0006 percent and it was at par with neem seed kernel extract 5 percent. Significantly higher seed yield was obtained in the treatment of neem seed kernel extract 5 per cent and it was at par with azadirachtin 0.15 EC 0.0006 percent. The highest ICBR was also recorded in the treatment of neem seed kernel extract at 5 percent.
Assessment of economic threshold level for onion thrips
Authors:   Regional Research Station, National Horticultural Research and Development Foundation (NHRDF), Karnal, Haryana, 132001, India., Pathak M. K. , Gupta P. K. ,   National Horticultural Research and Development Foundation (NHRDF), New Delhi 110058, India., Pandey S. ,   Regional Research StationNational Horticultural Research and Development Foundation (NHRDF), Nashik, Maharashtra,422003, India., Pandey M. K. ,   Regional Research StationNational Horticultural Research and Development Foundation (NHRDF), Nashik, Maharashtra,422003, India., Purshottaman S. ,   Regional Research Station, National Horticultural Research and Development Foundation (NHRDF), Karnal, Haryana, 132001, India., Gupta R. C. ,   Regional Research StationNational Horticultural Research and Development Foundation (NHRDF), Nashik, Maharashtra,422003, India., Dubey B. K. ,   Regional Research Station, National Horticultural Research and Development Foundation (NHRDF), Karnal, Haryana, 132001, India.
Published: January 2025

The present experiment was carried out the to determine the economic threshold level of onion thrips. The economic threshold level of T. tabaci is determined using the pesticide application technique. So the Economic Injury Level (EIL) of T. tabaci on onion plants can be determined as the number of thrips follows the value of ET levels for the detected peaks ranging between 4-5 individuals/leaf during the study. As the results of the pesticide application technique, the thrips mean numbers and mean yield of onion plants were correlated significantly during the two years. Results of chi-square analysis (R2) indicated that the values of the economic damage threshold of T. tabaci infested onion plants were 7 thrips/plant, while the economic injury level was 9.6 thrips/ plant during the study.
Effect of Different Tillage Practices on the growth and yield attributes of Potato (Solanum tuberosum L.)
Authors:   Senior Scientist and Head, Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Kushwah Sunita , Das Sripriya ,   Subject Matter Specialist (Crop Production), Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Gautam Prem Prakash ,   ubject Matter Specialist (Plant Protection), Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Namrata Kumari ,   Subject Matter Specialist (Agricultural Engg.), Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Verma Kavita ,   Krishi Vigyan Kendra, Vaishali, Bihar-844102, Subject Matter Specialist (Home Science), Krishi Vigyan Kendra, Vaishali, Bihar- 844102, India., Bharti Swapnil ,   Subject Matter Specialist (Horticulture), Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Singh Anup Kumar ,   Subject Matter Specialist (Animal Science), Krishi Vigyan Kendra, Vaishali, Bihar-844102, India., Kundu Madhu Sudan ,   Director Extension Education, DRPCAU, Pusa, Bihar-848125, India., Jat Raj Kumar ,   Principal Scientist, BISA, Pusa, Bihar-848125, India.
Published: January 2025

An experiment was conducted in Randomized Complete Block Design (RCBD) with 8 replications and three treatments viz. [T0= Conventional Cultivation (Control),T1= Zero Tillage Potato and T2=Raised Bed Potato). All the growth attributes (plant height, leaf area and plant cover area) recorded were significantly higher in case of conventional cultivation as compared to zero tillage and raised bed planting. However, the yield obtained was significantly higher for zero tillage potato (327.42 q/ha) in comparison to conventional cultivation (216.03 q/ha) and raised bed planting (283.98 q/ha). Thus, it can be concluded that zero tillage method of potato cultivation is better as compared to raised bed planting and conventional potato cultivation both in term of economical and environmental aspect. Economically, maximum B:C ratio of 3.63 is obtained under zero tillage potato and environmentally, it is an option for residue management and emits no harmful gases into the atmosphere due to no machinery use. Also, the benefits of mulching is additional in zero tillage system rendering better soil health in the long run.