bluuebunny/crossref_metadata_2025 huggingface dataset:
Identifying the Hub Genes and Immune Cell Infiltration in Synovial Tissue between
Osteoarthritic and Rheumatoid Arthritic Patients by Bioinformatic Approach
Authors: Wang Junjie , Fan Qin , Yu Tengbo , Zhang Yingze
Published: November 2021

Background:

Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common diseases that result
in limb disability and a decrease in quality of life. The major symptoms of OA and RA are pain, swelling, stiffness,
and malformation of joints, and each disease also has unique characteristics.

Objective::

To compare the pathological mechanisms of OA and RA via weighted correlation network analysis
(WGCNA) and immune infiltration analysis and find potential diagnostic and pharmaceutical targets for the
treatment of OA and RA.

Methods:

The gene expression profiles of ten OA and ten RA synovial tissue samples were downloaded from
the Gene Expression Omnibus (GEO) database (GSE55235). After obtaining differentially expressed genes
(DEGs) via GEO2R, WGCNA was conducted using an R package, and modules and genes that were highly
correlated with OA and RA were identified. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes
(KEGG) enrichment, and protein–protein interaction (PPI) network analyses were also conducted. Hub genes
were identified using the Search Tool for the Retrieval of Interacting Genes (STRING) and Cytoscape software.
Immune infiltration analysis was conducted using the Perl program and CIBERSORT software.

Results:

Two hundred ninety-nine DEGs, 24 modules, 16 GO enrichment terms, 6 KEGG pathway enrichment
terms, 10 hub genes (CXCL9, CXCL10, CXCR4, CD27, CD69, CD3D, IL7R, STAT1, RGS1, and ISG20), and
8 kinds of different infiltrating immune cells (plasma cells, CD8 T cells, activated memory CD4 T cells, T
helper follicular cells, M1 macrophages, Tregs, resting mast cells, and neutrophils) were found to be involved
in the different pathological mechanisms of OA and RA.

Conclusion:

Inflammation-associated genes were the top differentially expressed hub genes between OA and
RA, and their expression was downregulated in OA. Genes associated with lipid metabolism may have upregulated
expression in OA. In addition, immune cells that participate in the adaptive immune response play an important
role in RA. OA mainly involves immune cells that are associated with the innate immune response.
Psychological foundations of decision-making in the field of financial activity
Authors: Gnevanov Mikhail , Chernikova Maria Nikolaevna , Vetrova Tatyana Vyacheslavovna , Kosnikov Sergey Nikolaevich , Grigoriev Alexander Vladimirovich , Krekova Marina Mikhailovna
Published: November 2021

The article examines the psychological foundations of decision-making in the field of financial activity. It was concluded that the psychological foundations of the formation of financial self-control are based on personal perception of the situation with the planning and distribution of finances. One's own awareness of the process of the need to organize financial control for oneself as such is more effective than other borrowed strategies. Having come to the conclusion that it is necessary to control their financial income and expenses, a person can create a system for himself that will allow him to form his own budget, make financial decisions in a timely and competent manner, as well as develop his own financial behavior strategy that makes it possible to build a progressively developing system of expenses and financial income. Financial self-discipline strategies are used spontaneously and often. However, when it comes to the effectiveness of these strategies to achieve financial goals, the personal strategies that people have already used outperformed the strategies suggested to them in the study.
Effect of animation and review video making (arvima) in non-classical learning model on independent learning and students’ learning outcome
Authors: Azzajjad Muhammad Fath , Tendrita Miswandi , Ahmar Dewi Satria
Published: November 2021

The non-classical learning model used in this study was a jigsaw type cooperative learning model with the assignment treatment of making learning material video which is expected to make it easier in finding knowledge in teaching materials, with the creativity of students’ forming skills. The purpose of this study are to determine: (a) the effect of animation video and review video making in non-classical learning model on the ability to learn independently of students of the chemistry education study program at USN Kolaka, (b) the effect of animation video and review video making in non-classical learning model on the ability of spatial independence of students in the chemistry education study program at USN Kolaka, and (c) the effect of animation video and review video making in non-classical learning model on the learning outcome of students in the chemistry education study program at USN Kolaka. This research was a quasi-experimental research (quasy experiment) with a posttest only research design. The research population was students in the IV and VI semester of Chemistry Education Study Program. The instrument used was a questionnaire of learning independence, spatial ability and learning outcome.
methodological conflict between theory and philosophy of law
Authors: Shestopal Sergey S. , Kazachanskaya Elena A. , Kachurova Svetlana V. , Kachurov Evgeniy V.
Published: November 2021

The subject of this research is the recently intensified competition in modern jurisprudence of two equally respectable scientific disciplines: philosophy of law and theory of law. The goal is to demarcate the meaning of these concepts. Their ontological status (essential significance) in relation to the existence of the law, the reflection of which they are, is also considered. Based on analysis of the existential criticism of the dominant forms of modern ideology, it is proved that the existing theories of law depend on these forms. A stable tendency in modern philosophy to return legal science to the origins of philosophical knowledge of legal reality is stated.
Political pluralism as a factor in the development of modern society and state
Authors: Andreev Sergey D. , Bitsieva Emma V. , Lepeshkina Olga V. , Polonsky Dmitry M. , Savchenko Marina S.
Published: November 2021

This paper presents the results of a study devoted to the legal phenomenon of political pluralism as a factor in the development of modern society and the state by the example of classical democratic countries. At the same time, attention is focused on such components of political pluralism as formalization of freedom of speech and assembly; a multi-party system, as well as a mechanism for coordinating the interests of various social groups at the parliamentary level. It was found that the most acceptable is the model operating in the FRG, since it allows people to find a balance between guarantees of political diversity, such as freedom of speech and the right to public events. The interaction between civil society institutions and parliamentarians is especially advisable when making decisions in the domestic and foreign policy of the state.
Pengembangan perangkat pembelajaran berbasis etnomatematika yang berorientasi pada kemampuan literasi matematis siswa SMP
Authors: Ristanti Anisa Mita , Murdiyani Nila Mareta
Published: November 2021

Tujuan dilakukannya penelitian ini adalah untuk mengembangkan perangkat pembelajaran berbasis etnomatematika yang berorientasi pada kemampuan literasi matematis siswa SMP yang memiliki kualifikasi valid, praktis, dan efektif pada materi bangun ruang sisi datar. Penelitian ini menggunakan metode penelitian mixed methods dengan prosedur penelitian pengembangan model ADDIE. Objek dalam penelitian ini adalah siswa kelas VIII SMP Negeri di Kabupaten Wonosobo, Jawa Tengah. Instrumen yang digunakan adalah lembar validasi, angket respon siswa, lembar observasi keterlaksanaan pembelajaran, dan soal tes kemampuan literasi matematis. Hasil penelitian menunjukkan bahwa: 1.) Perangkat pembelajaran dinyatakan valid ditunjukkan dengan hasil penilaian RPP memperoleh skor 120 yang termasuk dalam kriteria sangat baik dan hasil penilaian LKS memperoleh skor 159 yang termasuk dalam kriteria sangat baik; 2.) Perangkat pembelajaran dinyatakan praktis ditunjukkan dengan skor rata-rata pada angket respon siswa 65,13 yang termasuk dalam kriteria cukup baik dan persentase keterlaksaan pembelajaran sebesar  89% yang termasuk dalam kriteria sangat baik; dan 3.) Perangkat pembelajaran dinyatakan efektif ditunjukkan dengan terjadinya peningkatan rata-rata nilai pretest ke posttest, yaitu dari 64,22 ke 83,67 serta persentase ketuntasan siswa pada posttest 84% yang termasuk dalam kriteria cukup baik.Development of ethnomathematical-based learning tools oriented to the mathematical literacy skills of junior high school studentsAbstractThe purpose of this research is to develop a mathematics learning set based on ethnomathematics oriented on mathematical literacy skills of junior high school students who have valid, practical, and effective qualifications on polyhedron subjects. This research uses mixed methods research method with ADDIE model development research procedures. The object of this research is students of class VIII SMP Negeri in Wonosobo Regency, Centra1 Java. The instruments used were validation sheets, student response questionnaires, learning implementation observation sheets, and mathematical literacy skill test questions. The results showed that: 1.) The learning sets are declared valid, indicated by the results of the lesson plan (RPP) assessment obtaining a score of 120, which was included in the very good criteria, and the results of the student worksheet (LKS) assessment obtaining a score of 159 which was included in the very good criteria; 2.) The learning sets are declared practical as indicated by the score on the student response questionnaire of 65,13, which was included in the criteria quite well. The percentage of learning implementation of 89%, included  in the very good criteria; and 3.) The learning sets are declared effective as indicated by an increase in the score from pretest to posttest, from 64,22 to 83,67, and the percentage of students’ completeness on the posttest also met the minimum criteria of good enough, which was 84%.
Efektifitas multimedia pembelajaran interaktif PKK dalam meningkatkan kreativitas berwirausaha siswa SMK
Authors: Handaru Calista Devi , Pujiriyanto Pujiriyanto
Published: November 2021

Penelitian ini bertujuan untuk mengetahui keefektifan multimedia pembelajaran interaktif dalam meningkatkan kreativitas berwirausaha siswa SMK. Penelitian ini merupakan jenis penelitian kuantitatif dengan menggunakan metode eksperimen. Desain penelitian yang digunakan dalam penelitian ini adalah Pre-Experimental Design dengan model One-Group Pretest-Posttest Design. Populasi dalam penelitian ini adalah semua siswa Klaten kelas XI Program Keahlian Bisnis Daring dan Manajemen Jurusan Akuntansi dan Keuangan Lembaga (AKL) dengan sampel sebanyak 30 siswa dengan jumlah perwakilan perkelas sebanyak 10 siswa. Teknik pengumpulan data yang digunakan yaitu tes. Tes berisi soal yang mengukur kreativitas berwirausaha siswa melalui lima aspek; 1) keaslian (originality), 2) kelancaran (fluency), 3) keluwesan (fleksibility), 4) Penguraian (elaboration), dan 5) Perumusan kembali (redefinition). Teknik analisis data yang digunakan dalam penelitian ini yaitu analisis deskriptif kuantitatif. Hasil penelitian menunjukan bahwa multimedia pembelajaran interaktif PKK memiliki efektivitas yang tinggi dalam meningkatkan kreativitas berwirausaha siswa yang dibuktikan dengan adanya peningkatan rerata skor pada posttest di setiap aspek kreativitas berwirausaha dan hasil uji wilcoxon memperoleh nilai Asymp.Sig. (2-tailed) 0,05 di semua aspek kreativitas berwirausaha. Hal ini berarti multimedia pembelajaran interaktif PKK dapat dijadikan sebagai alternatif media pembelajaran mata pelajaran PKK dalam meningkatkan kreativitas berwirausaha siswa SMK. Kata Kunci: multimedia pembelajaran interaktif, PKK, kreativitas berwirausaha
Metode Cooperative Learning dalam Meningkatkan Kualitas Hasil Belajar Siswa pada Masa Pandemi Covid-19
Authors: Prasetyawati Vianita
Published: November 2021

Pandemi Covid-19 telah berpengaruh besar dalam bidang pendidikan, sebab demi menghentikan penyebaran virus Covid-19 semua siswa dan guru harus melakukan kegiatan belajar mengajar (KBM) dari rumah. Guru sebagai penentu kemajuan pendidikan dituntut untuk lebih kreatif dan inovatif dalam memilih metode pembelajaran yang tepat agar hasil belajar siswa dapat ditingkatkan. Penelitian studi kepustakaan ini bertujuan untuk mengetahui kualitas hasil belajar siswa melalui metode cooperative learning di sekolah pada masa pandemi Covid-19. Metode yang digunakan dalam penelitian ini adalah penelitian studi kepustakaan dengan pendekatan penelitian deskriptif kualitatif. Metode  penelitian deskriptif kualitatif merupakan sebuah jenis penelitian yang memanfaatkan data kualitatif kemudian dijabarkan secara deskriptif. Penelitian deskriptif kualitatif menggambarkan kondisi yang sebenarnya tanpa memberi perlakuan atau memanipulasi variabel yang diteliti. Pada penelitian ini hasil analisis yang dilakukan oleh penulis yaitu setelah menggunakan metode cooperative learning terjadi peningkatan kualitas hasil belajar yang optimal. Hal ini membuktikan bahwa metode cooperative learning berdampak positif terhadap pembelajaran yaitu dapat meningkatkan kualitas hasil belajar siswa, baik dilihat dari tingkat partisipasi, interaksi dalam pembelajaran, hasil kuis dan tes, serta hasil tugas kerja kelompok. Selain itu, secara umum siswa juga menyukai metode cooperative learning karena dianggap banyak memberikan manfaat. Kesimpulan dari penelitian ini yaitu metode cooperative learning merupakan metode pembelajaran yang memberikan kesempatan bagi siswa untuk berpikir kritis, menjawab pertanyaan, berbagi pendapat serta meningkatkan aktivitas belajar siswa dan meningkatkan aktivitas guru dalam mengajar.
Pengaruh Penggunaan Brainly Terhadap Hasil Belajar Siswa
Authors: Nugroho Rafif Aditya
Published: November 2021

kemajuan teknologi yang sangat cepat dari waktu ke waktu kadang juga dapat menimbulkan dampak negatif. Dikhawatirkan para siswa didukung oleh kecanggihan yang diberikan kemajuan teknologi saat ini. Tujuan penelitian ini adalah untuk mengetahui seberapa besar pengaruh penggunaan brainly terhadap hasil belajar siswa saat pembelajaran disekolah. Metode yang digunakan adalah metode penelitian kuantitatif dengan teknik pengumpulan data berupa penyebaran kuesioner. Hasil dari penlitian ini adalah Brainly menjadi sebuah platform yang sering digunakan para siswa dalam membantu menyelesaikan pekerjaan sekolah mereka. Dari penelitian ini Brainly terbukti dapat meningkatkan hasil belajar siswa, namun disamping itu juga berdampak negatif terhadap cara belajar siswa dikelasKata Kunci: kemajuan teknologi, siswa, brainly, hasil belajar
Pengembangan Puzzle Berbasis Augmented Reality untuk Penanaman Nilai Pancasila bagi Siswa Kelas 4 SD IT
Authors: Halimah Nifta Noor , Sungkono Sungkono
Published: November 2021

Penelitian ini bertujuan untuk: (1) Menghasilkan Alat Permainan Edukatif puzzle Puzila berbasis augmented reality sebagai penanaman nilai-nilai pancasila di kelas 4 SD IT Bina Insan Kamil, dan (2) Mengetahui kelayakan Alat Permainan Edukatif puzzle Puzila berbasis augmented reality berdasarkan validasi dari ahli materi dan ahli media. Penelitian ini merupakan penelitian pengembangan APE yang dikembangkan dengan menggunakan model 4-D dari Thiagarajan. Subjek penelitian ini adalah siswa kelas 4 SD IT Bina Insan Kamil, Turi, Sleman, Yogyakarta yang berjumlah 12 anak. Teknik analisis data dalam penelitian ini menggunakan teknik deskriptif kuantitatif untuk mengetahui kelayakan dari media. Berdasarkan hasil penelitian yang sudah dilakukan maka pengembangan APE Puzzle Puzila telah menempuh 4 langkah dari model 4-D dari Thiagarajan yaitu tahap Define (Pendefinisian), Design (Perancangan), Develop (Pengembangan), dan Disseminate (Penyebarluasan). Hasil penelitian membuktikan bahwa media Puzzle Puzila layak untuk digunakan untuk siswa kelas 4 SD IT Bina Insan Kamil dalam materi penanaman nilai-nilai pancasila. Hal tersebut terbukti dari hasil validasi ahli materi yang memperoleh skor rata-rata sebesar 4,1 (Layak), validasi ahli media dengan perolehan skor rata-rata sebesar 4,3 (Layak), validasi guru dengan perolehan skor rata-rata sebesar 4,2 (Layak) dan tahap uji coba siswa diperoleh skor rata-rata dari data respon sebesar 1 (Layak).
KONTRIBUSI MOTIVASI BELAJAR DAN LINGKUNGAN BELAJAR TERHADAP HASIL BELAJAR PADA MATA PELAJARAN KESELAMATAN DAN KESEHATAN KERJA (K3) DI SMK NEGERI 1 MAGELANG TAHUN AJARAN 20192020
Authors: Kristiyanto Dwi Apri , Tawarjono Tawarjono
Published: November 2021

Penelitian ini bertujuan untuk mengetahui: (1) Kontribusi Motivasi Belajar terhadap Hasil Belajar siswa Teknik Kendaraan Ringan SMK Negeri 1 Magelang, (2) Kontribusi Lingkungan Belajar terhadap Hasil Belajar siswa Teknik Kendaraan Ringan SMK Negeri 1 Magelang, (3) Kontribusi Motivasi Belajar dan Lingkungan Belajar secara bersama-sama terhadap Hasil Belajar siswa Teknik Kendaraan Ringan SMK Negeri 1 Magelang.Populasi dalam penelitian ini adalah siswa kelas X TKR SMK Negeri 1 Magelang, dengan jumlah 96 siswa, sehingga penelitian ini merupakan penelitian populasi. Pengumpulan data dilakukan dengan angket dan dokumentasi. Angket untuk mengumpulkan data Motivasi Belajar dan Lingkungan Belajar sedangkan dokumentasi untuk mengambil data Hasil Belajar. Uji coba instrumen ini dilakukan terhadap 30 siswa kelas X TKR A SMK Negeri 1 Magelang, analisis data yang digunakan adalah teknik analisis regresi sederhana untuk hipotesis pertama dan hipotesis kedua serta analisis regresi ganda untuk hipotesis ketiga. Sebelum analisis data terlebih dahulu diadakan pengujian persyaratan analisis meliputi uji normalitas, uji multikolinieritas dan uji liniearitas.Hasil penelitian ini adalah: (1) Motivasi Belajar secara parsial memiliki kontribusi sebesar 21,7% terhadap Hasil Belajar siswa. Uji signifikansi menggunakan Uji t dengan hasil penghitungan yang menunjukan nilai thitung lebih besar dari ttabel (8,996>1,985) pada taraf signifikansi 0,05 dengan koefisien korelasi sebesar 0,680 sehingga dikatakan kontribusinya signifikan. (2) Lingkungan Belajar secara parsial memiliki kontribusi sebesar 32,6% terhadap Hasil Belajar siswa. Uji signifikansi menggunakan Uji t dengan hasil penghitungan yang menunjukan nilai thitung lebih besar dari ttabel (9,780>1,985) pada taraf signifikansi 0,05 dengan koefisien korelasi sebesar 0,710 sehingga dikatakan kontribusinya signifikan. (3) Motivasi Belajar dan Lingkungan Belajar secara simultan memiliki kontribusi sebesar 54,3 terhadap Hasil Belajar siswa. Uji signifikansi menggunakan Uji F dengan hasil penghitungan yang menunjukan nilai Fhitung lebih besar dari Ftabel (55,270>3,09) pada taraf signifikansi 0,05 dengan koefisien determinasi sebesar 0,543 sehingga dikatakan kontribusinya signifikan.
Factors Affecting Physicians’ Credibility on Twitter When Sharing Health Information: Online Experimental Study (Preprint)
Authors: Ferrell DaJuan , Campos-Castillo Celeste
Published: November 2021

BACKGROUND

Largely absent from research on how users appraise the credibility of professionals as sources for the information they find on social media is work investigating factors shaping credibility within a specific profession, such as physicians.

OBJECTIVE

We address debates about how physicians can show their credibility on social media depending on whether they employ a formal or casual appearance in their profile picture. Using prominence-interpretation theory, we posit that formal appearance will affect perceived credibility based on users' social context—specifically, whether they have a regular health care provider.

METHODS

For this experiment, we recruited 205 social media users using Amazon Mechanical Turk. We asked participants if they had a regular health care provider and then randomly assigned them to read 1 of 3 Twitter posts that varied only in the profile picture of the physician offering health advice. Next, we tasked participants with assessing the credibility of the physician and their likelihood of engaging with the tweet and the physician on Twitter. We used path analysis to assess whether participants having a regular health care provider impacted how the profile picture affected their ratings of the physician’s credibility and their likelihood to engage with the tweet and physician on Twitter.

RESULTS

We found that the profile picture of a physician posting health advice in either formal or casual attire did not elicit significant differences in credibility, with ratings comparable to those having no profile image. Among participants assigned the formal appearance condition, those with a regular provider rated the physician higher on a credibility than those without, which led to stronger intentions to engage with the tweet and physician.

CONCLUSIONS

The findings add to existing research by showing how the social context of information seeking on social media shapes the credibility of a given professional. Practical implications for professionals engaging with the public on social media and combating false information include moving past debates about casual versus formal appearances and toward identifying ways to segment audiences based on factors like their backgrounds (eg, experiences with health care providers).
Loneliness and Social Isolation Detection Using Passive Sensing Techniques: Scoping Review (Preprint)
Authors: Qirtas Malik Muhammad , Zafeiridi Evi , Pesch Dirk , White Eleanor Bantry
Published: November 2021

BACKGROUND

Loneliness and social isolation are associated with multiple health problems, including depression, functional impairment, and death. Mobile sensing using smartphones and wearable devices, such as fitness trackers or smartwatches, as well as ambient sensors, can be used to acquire data remotely on individuals and their daily routines and behaviors in real time. This has opened new possibilities for the early detection of health and social problems, including loneliness and social isolation.

OBJECTIVE

This scoping review aimed to identify and synthesize recent scientific studies that used passive sensing techniques, such as the use of in-home ambient sensors, smartphones, and wearable device sensors, to collect data on device users’ daily routines and behaviors to detect loneliness or social isolation. This review also aimed to examine various aspects of these studies, especially target populations, privacy, and validation issues.

METHODS

A scoping review was undertaken, following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Studies on the topic under investigation were identified through 6 databases (IEEE Xplore, Scopus, ACM, PubMed, Web of Science, and Embase). The identified studies were screened for the type of passive sensing detection methods for loneliness and social isolation, targeted population, reliability of the detection systems, challenges, and limitations of these detection systems.

RESULTS

After conducting the initial search, a total of 40,071 papers were identified. After screening for inclusion and exclusion criteria, 29 (0.07%) studies were included in this scoping review. Most studies (20/29, 69%) used smartphone and wearable technology to detect loneliness or social isolation, and 72% (21/29) of the studies used a validated reference standard to assess the accuracy of passively collected data for detecting loneliness or social isolation.

CONCLUSIONS

Despite the growing use of passive sensing technologies for detecting loneliness and social isolation, some substantial gaps still remain in this domain. A population heterogeneity issue exists among several studies, indicating that different demographic characteristics, such as age and differences in participants’ behaviors, can affect loneliness and social isolation. In addition, despite extensive personal data collection, relatively few studies have addressed privacy and ethical issues. This review provides uncertain evidence regarding the use of passive sensing to detect loneliness and social isolation. Future research is needed using robust study designs, measures, and examinations of privacy and ethical concerns.

CLINICALTRIAL
Preeclampsia, embarazo y COVID-19
Authors: Fortoul van der Goes Teresa I.
Published: November 2021

Además de las poblaciones que ya se identifican como en riesgo, hay que incluir a las mujeres embarazadas. Como indica la literatura médica, un embarazo normal presenta factores que pueden favorecer la infección por el SARS-CoV-2 y acompañarse de complicaciones como la preeclampsia. Seguir las indicaciones del empleo del cubrebocas y la vacunación junto con el control prenatal, ayudará a disminuir desenlaces negativos que pueden prevenirse
Preeclampsia: una mirada a una enfermedad mortal
Authors: Velumani Varsha , Durán Cárdenas Cassandra , Hernández Gutiérrez Laura Silvia
Published: November 2021

Si bien es poco frecuente, esta complicación del embarazo caracterizada por presión arterial alta y signos de daños en otro sistema de órganos como hígado, riñones y cerebro puede ocurrir en las mujeres a partir de la semana 20 del embarazo. Son muchos los factores que pueden llevar a que se desarrolle preeclampsia incluso en mujeres cuya presión arterial había sido normal. Además, una mujer puede pasar de tener una preeclampsia leve a una forma grave que cause problemas de salud graves para ella y el bebé. Esta revisión nos da una mirada actualizada a esta enfermedad mortal.
Green Marketing and Sustainability: Opportunities and Challenges
Authors: Hakim Prof. Iqbal Ahmed
Published: November 2021

Abstract: Green Business, Sustainable lifestyle, environmental protection are the buzz words that we hear nowadays. Sustainable development is a development that aims at sustainable consumption of resources and sustainable economic growth while protecting the natural environment. The term sustainable development basically comprises of three main constituents which are: environmental sustainability, economic sustainability, and socio-political sustainability. Owing to the fact that people are getting more and more inclined towards preserving the environment, businesses are busy devising strategies that can satisfy the needs of the society as well as be profitable. Green Marketing is one such strategy that has emerged as a key concept in India and other developing and developed countries as the main element for facilitating sustainable development. This research paper, aims at emphasizing the concept, need and importance of green marketing. Data is collected from multiple sources such as books, journals, websites, and news papers. The paper describes the present scenario of Indian market and search for various opportunities and issues businesses face while incorporating green marketing. The paper also explains the reasons why businesses are adopting it on a high scale and its future in the emerging markets. The paper concludes with the insight that green marketing will grow on a continuous basis both in practice as well as demand. Keywords: Sustainable Development, Green Marketing, Sustainability, Economic Sustainability, Green Business
Comparative seismic analysis study of G+ 20 story building with flat slab and conventional slab using ETABS
Authors: Mohite Mr. Nitish A.
Published: November 2021

Abstract: In the study, three dimensional analytical models of G+20 story buildings have been generated and analysed using CSI ETABS software version 2016. The earthquake zone III in India is considered for buildings during analysis. Here, the analysis and design is done of G+20 story building with flat slab(with drops) and conventional slab system. In earthquake zone the displacement and drift of the structures will be more so to have more stiffness to the structure shear wall is to be provided therefore a study is made by comparing between conventional slab & flat slab (with drops) building. Comparison of various parameters like story drift, story displacement, story stiffness and time period is done. The equivalent static method is used to design and analyze the structures, as categorized by Indian Standard Code for earthquake resistant structures. The study shows that story drift is 10% more in conventional slab as compared to flat slab; story displacements is observed linearly increasing with height of the building and is 11% more in conventional slab as compared to flat slab . Keywords: Equivalent Static Method, Flat Slab, ETABS 2016, story displacement, story stiffness, story drift, time period
Inovasi Pembelajaran Metode Konvensional dikombinasikan dengan Metode PBL
Authors: Rahmawati Rahmawati , Supriadi Ghaida Sekarlita Fadha , Pratiwi Purnamaulida , Riandi Riandi , Supriatno Bambang
Published: November 2021

This article was to find out the innovation of students by using combination of Conventional Method and PBL Method. Based on the result of Classroom Action Research found that there was a differences between pre-test, post-test whether Cycle I or Cycle II. Based on the result, the writer concluded that the result of this research was the result of post-test in Cycle I was lower than post-test in Cycle II with the combination of Conventional Method and PBL Method.
Abstrak. Artikel ini bertujuan untuk mengetahui inovasi siswa dengan menggunakan kombinasi Metode Konvensional dan Metode PBL. Berdasarkan hasil Penelitian Tindakan Kelas ditemukan bahwa ada perbedaan antara pre-test, post-test apakah Siklus I atau Siklus II. Berdasarkan hasil tersebut, penulis menyimpulkan bahwa hasil dari penelitian ini adalah hasil posttest siklus I lebih rendah dari posttest siklus II kombinasi metode konvensional dan metode PBL.
Analisis Tingkat Kesulitan Belajar Matematika Siswa dalam Menggunakan Prinsip Matematis
Authors: Pramesti Cicik , Prasetya Ariesandi
Published: November 2021

Di dunia pendidikan masih ditemukan siswa mengalami kesulitan belajar matematika. Kesulitan belajar matematika merupakan suatu kondisi, seseorang tidak mampu belajar matematika dengan baik terkait dalam menyebutkan hal-hal yang diketahui dan yang ditanyakan, kalkulasi, serta penerapan rumus. Berdasarkan keadaan tersebut peneliti melakukan penelitian yang bertujuan untuk menganalisis kesulitan belajar matematika dalam menggunakan prinsip matematis pada materi determinan dan invers matriks. Kesulitan tersebut dianalisis berdasarkan indikator kesulitan belajar matematika dalam menggunakan prinsip matematis (1) kesalahan perhitungan atau operasi aljabar, (2) tidak mampu menentukan data yang relevan, dan (3) tidak dapat menerapkan rumus. Jenis penelitian adalah deskriptif kualitatif, dengan instrumennya tes dan wawancara. Deskripsi hasil analisis kesulitan belajar matematika dalam menggunakan prinsip matematis adalah pada indikator: (1) kesalahan penghitungan masih berada pada kriteria tingkat tinggi, sehingga kemampuan berhitung masih perlu ditingkatkan kembali khususnya dalam hal ketelitian, kecermatan, serta kehati-hatian; (2) ketidakmampuan menentukan data yang relevan berada pada kriteria tingkat sedang, namun kemampuan ini masih dapat ditingkatkan kembali dengan cara pembiasaan menuliskan hal-hal yang diketahui dan yang ditanyakan untuk mempermudah menyelesaikan permasalahan; dan (3) tidak dapat menerapkan rumus berada pada kriteria tingkat rendah, yang didominasi oleh siswa berkemampuan rendah. Kesulitan ini dapat diminimalkan dengan cara pembimbingan langsung oleh guru dan atau melalui tutor sebaya.
Effectiveness of Problem Based Learning (PBL) on Mathematics Learning Achievement in terms of Student Adversity Quotient (AQ)
Authors: Lusiana Restu , Suprapto Edy , Sukristini Ika
Published: November 2021

Innovative learning models have an influence on student achievement. This study aims to determine whether the PBL learning model is more effective than the STAD learning model (learning model that has been applied in schools) on mathematics learning achievement, whether there is a difference in the effect of the AQ of climber, camper, and quitter category students on mathematics learning achievement, and whether there is the interaction between the learning model and students' AQ on mathematics learning achievement. This research is in the form of quantitative research. The sample was taken using a simple random sampling technique where the experimental class was taught using the PBL learning model and the control class was taught using the STAD learning model. The data collection technique used the Questionnaire method for AQ data and the test method for students' mathematics learning achievement data. The data technique used a two-way unequal cell analysis of variance test with a 2×3 matrix and a further test using the Scheffe test. The results of hypothesis testing with a significance level (α) = 5% indicate that there is a difference in the effect of the learning model on mathematics learning achievement (Fobs=19.97 and Fα=4.13), there are differences in the effect of each AQ category on mathematics learning achievement (Fobs=94.59 and Fα=3.28), and there is no interaction between the learning model and students' AQ on mathematics learning achievement (Fobs=2.39 and Fα=3.28).
Senyawa Turunan Terpenoid dari Ekstrak Aseton Daun Perepat (Sonneratia alba) dan Aktivitasnya Terhadap Escherichia coli
Authors: Muhaimin Muhaimin , Ningsih Kurnia Nastira , Latief Madyawati
Published: November 2021

Perepat (Sonneratia alba) secara tradisional masih digunakan untuk pengobatan luka, diare dan demam. Diare disebabkan oleh Escherichia coli. Daun perepat mengandung alkaloid, fenolat, triterpenoid, flavonoid, tanin, saponin, steroid dan glikosida. Terpenoid berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk isolasi senyawa turunan terpenoid dan uji aktivitasnya terhadap Escherichia coli. Proses isolasi dilakukan dalam 3 tahap yaitu kromatografi vakum cair, kromatografi kolom gravitasi pertama dan kromatografi kolom gravitasi kedua. Isolat F2.2.2 murni sebagai kristal putih tajam. Titik leleh isolat F2.2.2 pada 210,2-211,1 Â°C. Hasil spektrofotometer UV-Vis memiliki serapan maksimum pada 203 nm dan 212 nm yang menunjukkan adanya transisi elektron Ï€â†’Ï€* yang menunjukkan adanya gugus kromofor yang khas pada sistem ikatan rangkap C=C terisolasi. Hasil interpretasi data FTIR menunjukkan senyawa memiliki gugus -OH (3277,20 cm-1), -C-O (1047,39 cm-1), -C=C terisolasi (1656,92 cm-1), -C-H alifatik (2896,24 cm-1) dan gem dimetil (1463,07 cm-1 dan 1377,23 cm-1) sebagai karakteristik senyawa triterpenoid. Berdasarkan hal tersebut diduga isolat F2.2.2 merupakan senyawa turunan triterpenoid lupan yaitu Lupeol. Hasil uji aktivitas antibakteri terhadap Escherichia coli menunjukkan bahwa ekstrak aseton daun perepat memiliki aktivitas yang lemah, sedangkan isolat F2.2.2 tidak memiliki aktivitas.
EFEKTIVITAS KEPEKATAN LARUTAN SODIUM HYPOCHLORITE TERHADAP BIAKAN KUMAN STAPHYLOCOCCUS AUREUS
Authors: Effendi Fajar Ivan , Ernawan Rieva , Utomo Pamudji , Mariyanto Ismail , Santoso Asep
Published: November 2021

Abstract

Musculoskeletal infections have complex complications, making them a challenge. Most countries have experienced Staphylococcus aureus resistance to methicillin by 25% and some even over 50%. Dakin solution (0.050% to 0.025%) can be used as irrigation, cleansing, and used on moist gauze for the management or prevention of skin or tissue infections.

This study aims to determine the lowest concentration level of Dakin solution / sodium hypochlorite which is the safest and most effective in the culture of Staphilococcus aureus.

This research is an analytical experimental research, with the concept of comparing the Staphylococcus aureus ATCC 25923 germ cultures which are treated in the form of giving dakin solution / sodium hypochlorite 0.050%, 0.025%, 0.0125% and control using 0.9% NaCl. Observation of the effectiveness is done by measuring the formed inhibition zone.

The concentration of 0.025% gives a fairly good disinfectant effect with moderate inhibition power, the concentration of 0.050% gives a good disinfectant effect with a strong inhibitory power while the concentration of 0.0125% does not have a disinfectant effect, this is the same as the 0.9% NaCl control solution. The zone of inhibition in the staphylococcus aureus bacteria culture ATCC 25923 at concentrations of 0.025% and 0.050% still gave a stable effect until evaluation within 2x24 hours (48 hours).

Keywords : Dakin solution, Sodium hypoclorite, resistor zone, Staphylococcus aureus.
GAMBARAN USIA PADA KEJADIAN COVID-19
Authors: Elviani Rosyada , Anwar Chairil , Januar Sitorus Rico
Published: November 2021

Covid-19 adalah Pandemi yang baru terjadi di akhir tahun 2019 yang disebabkan oleh SARS CoV2. Hal ini harus diwaspadai karena transmisi yang cepat, memiliki tingkat kesakitan yang tidak dapat diabaikan. Sampai saat ini, belum ada vaksin pencegahan dan terapi definitif yang belum terbukti. Usia lanjut pada beberapa artikel disebutkan sebagai faktor risiko Covid-19.

Tujuan penelitian ini untuk mengetahui gambaran usia pada kejadian Covid-19. Merupakan penelitian kuantitatif dengan desain analitik observasional dengan pendekatan unmathced case control. Data yang digunakan adalah data sekunder rekam medik dan surveilans ruang isolasi RSUP Dr. M. Hoesin Palembang periode 1 Maret 2020 s/d 31 Juli 2020 yang berjumlah 666 responden.

Analisis data menggunakan univariat untuk mengetahui gambaran usia pada kejadian Covid-19. Hasil penelitian didapatkan bahwa dari 116 usia berisiko (>65 tahun) yang terkonfirmasi positif sebanyak 30 (40,2%) sisanya 49 (59,8%) negatif. Sedangkan dari 550 usia yang tidak berisiko,  sebanyak 277 (47,4%) terkonfirmasi positif dan sisanya 307 (52,6%) negative. Pada analisis bivariat, tidak ada hubungan yang signifikan secara statistik antara usia dengan Covid-19 dengan p value 0,270.

Kesimpulan.Semua usia berisiko terkonfirmasi positif Covid-19, dan usia produktif paling berisiko Covid-19 yang dikarenakan mobilitas dan aktifitas sosial yang tinggi. Hal ini dapat dicegah dengan tetap melakukan protokol kesehatan.
IMUNODEFISIENSI PRIMER DAN DETEKSI DININYA
Authors: Mahendra Cipta
Published: November 2021

Penyakit imunodefisiensi primer (primary immunodeficiency disease/PID) merupakan keadaan terjadinya defek sistem imun yang disebabkan mutasi pada kode genetik yang mengode komponen-komponen penyusun sistem imun tubuh. Kelainan ini tergolong jarang/langka namun menurunkan kualitas hidup atau bahkan bisa juga mengancam nyawa bagi penderita-penderitanya. Terapi definitif yang tersedia hingga kini pun juga masih terbatas dan berbiaya tinggi. Artikel ini dimaksudkan terutama bagi dokter umum/layanan primer sebagai pengantar agar mengenali penyakit ini sebagai sebuah kelainan langka, yang mungkin jarang atau bahkan belum pernah mendengar tentang keadaan ini sebelumnya.
ABDOMEN ULTRASONOGRAPHIC EXAMINATION ANALYSIS IN THE CASE OF URINARY BLADDER DIVERTICULA AT CILEGON HOSPITAL
Authors: Wirya Tirta , Sari Gando , Bahri Syamsul , Heru Nursama , Utami Resa Wantika
Published: November 2021

ABSTRACT

Diverticulum is outpouching of hollow (or fluid-filled) structures, which can form in various organs in the body. Increased intravesical pressure (3-5 times) causes the bladder mucosa to infiltrate itself between the bladder muscle bundles which results in the development of extravasational sacs or saccules which subsequently results in diverticulum formation. The sonographic diagnosis of bladder diverticula depends on the demonstration of communication between the bladder and the mass. When such communication, or estuary, is not seen during ultrasound examination, the bladder diverticulum can look like any other type of cystic pelvic mass.

The approach used is descriptive qualitative. This study aims to analyze the examination of the USG Abdomen with clinical bladder diverticula to get an appropriate picture of USG so that the diagnosis can be established. The study population was patients who performed an abdominal USG examination at the Cilegon Regional General Hospital. The sample of this study were 1 (one) patient. The method used in collecting data in this study is observation, documentation, and literature study.

Keywords: Ultrasound, Urinary Bladder, Diverticula
PENGARUH JARAK, KEMIRINGAN, DAN INTENSITAS CAHAYA PADA ANALISIS UKURAN PORI MASKER KAIN MENGGUNAKAN SMARTPHONE
Authors: Hamdini Meri , Sari Diana Novita , Susanti Susanti , Tiandho Yuant
Published: November 2021

One of the common strategies used to minimize the spread of Covid-19 is to wear a cloth mask. Cloth masks have a lower effectiveness value compared to other types of masks but have the potential to be used as an alternative, especially during a pandemic. Smartphone can be used as an initial idea for determining the quality of a cloth mask. In taking pore images, there are factors that have the potential to affect the results of pore size, namely distance, angle of inclination, and light intensity. Taking photos of masks with a magnification application is done with three variations, namely distance, angle, and light intensity. The distance for taking pore images is varied to 3, namely 8 cm; 10 cm; and 12 cm. The image capture angle is varied to 0p; 5o; and 10o. measurement using a distance of 10 cm has the closest value from the measurement results by taking images using a microscope, which is 0.232 mm. In the variation of the angle, the angle that is parallel or 0o to the plane of the cloth mask has a value that is close to the microscope measurement, which is 0.232 mm. The light intensity measured using a lux meter which shows the results of 240 has a value that is closest to taking an image using a microscope, which is 0.221 mm.
PEMBERDAYAAN MASYARAKAT DESA OLELE MELALUI PELATIHAN PEMBUATAN NUGET IKAN NIKE KELOR DAN CAKE KELOR
Authors: Solang Margaretha , Latjompoh Masra
Published: November 2021

Olele village in Kabila Bone district is among the villages located in the southern coastal area of the province of Gorontalo. The majority of people there work as fishermen and farmers. Nike fish (Awaous melanocephalus) and moringa (Moringa oleifera) are the common natural resources in Olele village. The objective of this mentoring project was to enhance the food processing skills of the local community by disseminating steps in processing moringa nike fish nugget and the potential of the leaves of a moringa as the ingredient of moringa leaf cake. Its steps included 1) preparation, 2) program implementation, and 3) evaluation. Based on the results, the mentoring program contributed to the enhancement of both knowledge and skills of the participants in processing nugget of moringa nike fish. The participants were also aware of the potential of the leaf moringa as an ingredient of a healthy diet. Further, all participants were able to make moringa nike fish nugget and moringa leaf cake. These two food products received a positive reception from all panelists. In the end, all participants would improve all of the food products through their home-based food business. This was also to support the food business program in their village.
PENGEMBANGAN VIDEO IKLAN DI MEDIA SOSIAL UNTUK MENINGKATKAN PANGSA PASAR IKM DI KECAMATAN PELAYANGAN
Authors: Utomo Pradita Eko Prasetyo , Suratno Tri , Mauladi Mauladi , Saputra Edi , Hutabarat Benedika Ferdian
Published: November 2021

Pelayangan sub-district is a sub-district in Jambi City where the average income of the population is obtained from small and medium industries (IKM). The product produced is one of the typical products of the Jambi region, including crackers, batik, food, and others. Product marketing that has been carried out so far is still fixated using conventional methods. This is due to the limited knowledge of IKM managers in the Pelayangan District area in utilizing information technology to support the marketing process for the products they produce. With the use of social media and the development of video advertisements on social media, it is possible to expand market share and the resulting product sales transactions. For this reason, in order to expand market share, a community service program for the application of science and technology is carried out. Where in this service program, the development and implementation of assistance in the use of promotional media will be carried out in the form of product videos that are advertised premium on social media in order to expand market share in product sales to small and medium industries (IKM) in Pelayangan Kota District. Assistance activities will be carried out in 3 activity sessions located in Pelayangan District, namely 1 session of delivering material, ideas and ideas about product marketing through advertising services on social media and 2 sessions of making, implementing and mentoring the use of the media. The output resulting from this community service activity is an increase in community understanding and skills about promotion using social media and IKM product videos that are promoted through advertising services on social media
Penggunaan Campuran Magnesium Sulfat dan Arang Tempurung Kelapa Sebagai Upaya Perbaikan Resistansi Pentanahan Elektroda Jenis Batang
Authors: Tessal Dasrinal , Ardi Widiansyah , Nehru Nehru
Published: November 2021

Usaha dalam perbaikan tahanan pentanahan dapat dilakukan dengan berbagai cara. Salah satu caranya adalah dengan memakai magnesium sulfat dan arang tempurung kelapa. Kedua zat tersebut digunakan pada elektroda pentanahan berjenis tembaga dan pipa galvanis masing-masing tertanam 1 meter dari permukaan tanah. Zat kemudian ditambahkan pada lubang berdiameter 12 cm dengan elektroda atau pipa sebagai titik tengahnya. Tanah yang dipakai dalam penelitian berjenis tanah liat. Pengukuran nilai tahanan elektroda menggunakan metode 3 titik. Pengamatan dilakukan selama 7 hari dan dilakukan pada jam 9.00, 11.00, 13.00 dan 15.00. Nilai pengukuran tahanan pada elektroda tembaga tanpa perlakuan rata-rata bernilai 107 ohm dan dengan penambahan arang tempurung kelapa ,magnesium sulfat, , dan campuran keduanya masing-masingnya adalah 84,1 Ω, 62,9 Ω dan 79,3 Ω . Pada pipa galvanis nilai tahanan rata-rata awal sebelum penambahan zat sebesar 84,1 Ω setelah penambahan arang tempurung kelapa,magnesium sulfat dan campuran keduanya masing-masing bernilai 60,1 Ω , 38,8 Ω , dan 51,3 Ω .
The Application of K-Nearest Neighbours Algorithms for the Classification of Fashion Trend
Authors: Saputro Nugroho Dwi , Wibowo Setyoningsih , Darmaputra Mochamad Fadjar
Published: November 2021

The commerce department in indonesia has been formulating indonesia economic development plan creative explain about the evolution of the year 2025 creative economy, The shift from agriculture to the industrial era and the era of information and now entering the era of economic globalization. The development of industries create a pattern of work the production and distribution of cheap and more efficient. Fashion industry is one of the creative economy development Creative economy in many countries today encourage the people. Fashion or mode of itself is the activity associated with the design, the production of, consultation and the distribution of the product of fashion .Producers fashion industry composed of fashion clothing and accessories, fashion industry bag manufacturers, shoes and accessories. In clothes creation, the trend of being important aspect .Designers indonesia today still follow the trend of europe are affected by the type of the season. Decision-making on the basis of the data and accurate information will result in a decision to fashion trend clasification on creative industries can be done by adopting the approach of data mining. According to Tan Pang-Ning data mining is a process that done automatically to find information that is useful in a repository big data.