bluuebunny/crossref_metadata_2025 huggingface dataset:
Concussion-Recovery Trajectories Among Tactical Athletes: Results From the CARE Consortium
Authors: Van Pelt Kathryn L. , Allred C. Dain , Brodeur Rachel , Cameron Kenneth L. , Campbell Darren E. , D'Lauro Christopher J. , He Xuming , Houston Megan N. , Johnson Brian R. , Kelly Tim F. , McGinty Gerald , Meehan Sean K. , O'Donnell Patrick G. , Peck Karen Y. , Svoboda Steven J. , Pasquina Paul , McAllister Thomas , McCrea Michael , Broglio Steven P.
Published: June 2020

Context

Assessments of the duration of concussion recovery have primarily been limited to sport-related concussions and male contact sports. Furthermore, whereas durations of symptoms and return-to-activity (RTA) protocols encompass total recovery, the trajectory of each duration has not been examined separately.

Objective

To identify individual (eg, demographics, medical history), initial concussion injury (eg, symptoms), and external (eg, site) factors associated with symptom duration and RTA-protocol duration after concussion.

Design

Cohort study.

Setting

Three US military service academies.

Patients or Other Participants

A total of 10 604 cadets at participating US military service academies enrolled in the study and completed a baseline evaluation and up to 5 postinjury evaluations. A total of 726 cadets (451 men, 275 women) sustained concussions during the study period.

Main Outcome Measure(s)

Number of days from injury (1) until the participant became asymptomatic and (2) to complete the RTA protocol.

Results

Varsity athlete cadets took less time than nonvarsity cadets to become asymptomatic (hazard ratio [HR] = 1.75, 95% confidence interval = 1.38, 2.23). Cadets who reported less symptom severity on the Sport Concussion Assessment Tool, third edition (SCAT3), within 48 hours of concussion had 1.45 to 3.77 times shorter symptom-recovery durations than those with more symptom severity. Similar to symptom duration, varsity status was associated with a shorter RTA-protocol duration (HR = 1.74, 95% confidence interval = 1.34, 2.25), and less symptom severity on the SCAT3 was associated with a shorter RTA-protocol duration (HR range = 1.31 to 1.47). The academy that the cadet attended was associated with the RTA-protocol duration (P < .05).

Conclusions

The initial total number of symptoms reported and varsity athlete status were strongly associated with symptom and RTA-protocol durations. These findings suggested that external (varsity status and academy) and injury (symptom burden) factors influenced the time until RTA.
Dry Cupping Therapy for Improving Nonspecific Neck Pain and Subcutaneous Hemodynamics
Authors: Stephens Stephanie L. , Selkow Noelle M. , Hoffman Nicole L.
Published: June 2020

Context

Dry cupping therapy is a noninvasive treatment commonly used to reduce pain and promote the healing process in various populations, including those with nonspecific neck pain; however, no data are available to support most of this method's true physiological benefits.

Objective

To determine if dry cupping therapy decreased pain and increased subcutaneous blood flow compared with sham cupping and control conditions.

Design

Controlled laboratory study.

Setting

Laboratory.

Patients or Other Participants

A total of 32 participants (age = 22.5 ± 2.8 years, height = 173.3 ± 10.1 cm, mass = 76.6 ± 18.7 kg) with self-reported nonspecific neck pain.

Intervention(s)

We used dry cupping and sham cupping interventions and a control condition. For the dry cupping intervention, 1 stationary cup was placed directly over the most painful area for 8 minutes. The sham cupping intervention followed the same procedures as the dry cupping intervention except a sham cup was applied. For the control condition, participants received no treatment.

Main Outcome Measure(s)

Subjective pain intensity (visual analog scale); pain-pressure threshold; subcutaneous hemodynamics, including superficial and deep oxygenated, deoxygenated, and total hemoglobin levels; and tissue saturation index.

Results

We observed differences in the visual analog scale score and the superficial and deep oxygenated and total hemoglobin levels (P values ≤ .002) immediately postintervention compared with baseline. Post hoc tests revealed that the dry cupping group had less pain than the sham cupping and control groups and higher superficial and deep oxygenated and total hemoglobin levels (P values ≤ .008). No differences were found between baseline and 24 hours postintervention.

Conclusions

A single session of dry cupping therapy may be an effective short-term treatment method for immediately reducing pain and increasing oxygenated and total hemoglobin levels in patients with nonspecific neck pain.
Komparasi Effisiensi Pengereman Pengujian Rem Statis (Static Brake Test) Dan Pengujian Rem Jalan (Road Brake Test)
Authors: Pranoto Ethys , Miftahul Hidayat Aziz , Humami Faris , Nur Hakim M Iman
Published: June 2020

Keselamatan dan keamanan berkendara di jalan menjadi unsur utama dalam pelayanan jasa transportasi. Penyedia pelayanan jasa transportasi berkewajiban memastikan bahwa kendaraan yang dioperasikan memenuhi syarat teknis dan laik jalan kendaraan bermotor yang ditentukan oleh pemerintah. Salah satu syarat teknis dan laik jalan adalah terpenuhinya sistem rem yang berfungsi dan memenuhi ambang batas. Pengujian untuk memenuhi ambang batas dapat dilakukan dengan dua metode yaitu Static Brake Test dan Road Brake Test. Kedua metode yang berbeda akankah menghasilkan keluaran yang sama. Hasil komparasi kedua pengujian menunjukkan adanya perbedaan keluaran yang diperoleh dan hal ini dapat menimbulkan persepsi yang berbeda terhadap pemenuhan syarat teknis dan laik jalan kendaraan.
El uno y el ser. Mística de los nombres de Dios en Dionisio Areopagita
Authors: Palma Ramírez Manuel
Published: June 2020

En los capítulos tercero y cuarto de Sobre los nombres divinos, Dionisio desentraña el significado y el papel que poseen la unidad y el ser. Es un autor que, fruto de la absorción del pensamiento del neoplatonismo y de la tradición griega, ha marcado profundamente la filosofía y la teología medieval (y más allá). La reflexión del filósofo francés Jean-Luc Marion sobre la eminencia del nombre conduce a la consideración de la Bondad como expresión del don originario de Dios.
Effective Educational Leadership Training for Improving Student Learning Outcomes
Authors: Sebastien Neria
Published: June 2020

In the required course work of many programs in Educational Leadership, doctoral candidates typically engage in various forms of analysis and synthesis about transformative leadership. Coursework in ethical education; transformational learning; creativity, inquiry, and innovative leadership; quantitative research methods; qualitative research methods, and leading organizational change form the basis of many courses of study. Evidence in the literature overwhelmingly support the position that educational leaders are highly effective, when engaging in both transformational and organizational development practices. Their effectiveness can also benefit student learning outcomes. This paper draws from the main points of all of the afore mentioned to illustrate how the effective educational leadership training can benefit student transformative educational leaders. The paper concludes that investment in educational leadership training is a pathway for large-scale education improvement.
5. SINIF TÜRKÇE DERS KİTABININ ÖĞRETMEN GÖRÜŞLERİNE GÖRE DEĞERLENDİRİLMESİ
Authors: ARSLAN Aysel , ENGİN Ali Osman
Published: June 2020

Bu çalışmanın amacı 2017-2018
eğitim-öğretim yılında uygulamaya konulan 5. sınıf Türkçe Dersi Öğretim
Programı’na göre hazırlanan Türkçe ders kitabının öğretmen görüşlerine göre
değerlendirilmesidir. Araştırmaya dâhil edilen çalışma grubu 2017-2018
eğitim-öğretim akademik yılı bahar döneminde Gaziantep ili Şahinbey ilçesindeki
18 farklı ortaokulda MEB bünyesinde görev yapan 25 Türkçe öğretmeninden
oluşmaktadır. Araştırmada nitel araştırmalar için uygun olan durum çalışması
deseni kullanılmıştır. Araştırma verilerinin elde edilmesi amacıyla yarı
yapılandırılmış görüşme formu kullanılmıştır. Öğretmenlere, 5. sınıf Türkçe
ders kitabının, Türkçe dersi programında yer alan kazanımlara uygunluğu;
kitaptaki metinlerin öğrenci seviyesine uygunluğu, kitabın dil bilgisi
yapıları, içerdiği kelimeler, görseller vb. unsurlar yönünden
değerlendirilmesinin yapılması; kitaptaki etkinliklerin dersin kazanımlarına ve
öğrenci düzeyine uygunluğu; ölçme-değerlendirme açısından yeterliliği; ders
kitabını uygularken karşılaştıkları sorunlar; genel düşüncelerinin neler olduğu
sorulmuştur. Verilerin analizinde içerik analizi ve feekans analizi teknikleri
kullanılmıştır. Öğretmenlerin genel olarak 5. sınıf Türkçe ders kitabındaki
metinleri ve etkinlikleri kazanımlara, öğrenci düzeyine uygunluk açısından
olumlu değerlendirdikleri tespit edilmiştir. Öğretmenlerin Türkçe ders kitabını
uygularken karşılaştıkları başlıca sorunların; zaman sıkıntısı, materyal
eksikliği ve kılavuz kitabının olmaması olduğu belirlenmiştir. Öğretmenler
ayrıca Türkçe dersine ilişkin materyallerin bir an önce giderilmesi, kılavuz
kitaplarının yeniden verilmesi, program ve ders kitabı hazırlarken öğretmen
görüşlerine daha fazla yer verilmesi gerektiğini düşündüklerini ifade
etmişlerdir.
The Impact of Cassava Wastewater from Starch Processing Industry on Surrounding Soil: A Case Study of Matna Foods Industry, Ogbese
Authors: Adewumi J R , Babatola J O , Olayanju O K
Published: June 2020

This study is aimed at determining the impacts of indiscriminate disposal of processed cassava wastewater into the environment by determining the physicochemical characteristics of the wastewater and soil characteristics within the vicinity of starch processing industry.The cassava wastewaterquality wastested in accordance with the standard methods for the examination of water and wastewater while soil samples was analysed using Atomic Absorption Spectrometer. The result of cassava wastewatershows that the effluent is acidic with pH of 3.8 and high conductivity of 6500µΩ. The cyanide content is also very high with 0.17mg/l as compared to 0.05mg/l recommended by WHO. The total solid, total dissolved solid and total suspended solid are also in high range of 20619, 17048 and 3571 mg/l respectively. Its hardness is 812mg/l, chloride 2516mg/l and nitrate 470mg/l. The dissolved oxygen was not detected while COD and BOD were also on the high side with values of 560 and 1410mg/l respectively. The results of soil analysis indicates that the cyanide concentration is high at the surface but reduces with depth. The pH is also in acidic range. However, Magnesium, Sodium, Sulphate, Zinc, Chromium, Vanadium, Europium and Rubidium were not detected in the soil samples. The percentage of calcium, potassium, copper, manganese and titanium were small and varying between 0.07 and 6.37ppm. Three unlined aerobic ponds provided for the treatment of cassava wastewater reduces the pollution strength of the wastewater but the untreated wastewater interfere with the surrounding soil during conveyance to the pond as well as pond environment.It is recommended that the wastewater conveyance and ponds should be well designed to prevent interference with the surrounding soil.
Computer Aided Grain Aeration Management: an Antidote to Grain Deterioration in Metal Silo
Authors: Olorunfemi Bayode Julius , Adekunle Adefemi , Adejuyigbe Samuel
Published: June 2020

Aeration is very important for good grain storage as it helps to maintain uniform grain temperatures, minimizes moisture migration, and prevents quality loss of stored grain. The temperature of grain stock was monitored with the aid of temperature sensors installed inside the silo bins. Each silo contained twenty sensors located on five probes at different sections of the silo bin. Grain was received to experimented metal silos at 300C. The parameters for grain before reception were 1% broken grain, 1% mould, 1%  foreign matters, 68- 75KG/HL weight and 12% moisture content. Grain temperature rose to 450C within three weeks of storage. Temperature readings were taken in the morning and at evening times. Aeration system (fans) was operated several times, each time for long hours (≥5hours) enough to equalize temperature throughout the entire grain mass. Aeration fans were used to rapidly cool grain to 250C and then held it between 25 - 410C for over a year. The power requirement increased as air flow rate and grain depth increased. Aeration fans were controlled automatically from the operating control room while dehumidifiers were installed on the aeration fans. Loss recorded at manually operated metal silo was compared with the one from the silo monitored with computer software developed. While aeration could be used to lower grain temperature, minor changes took place on the moisture content of the grain mass. Loss was reduced to < 1% as against 5%. Aeration can be better monitored economically with the use of a computer system.
A Review of the Major Problem Soils in Nigeria
Authors: Bolarinwa Ademola , Ola Samuel
Published: June 2020

This paper intends to produce a compendium of geotechnical properties of major problem soils of Nigeria which have critical influence on the design, performance, lifespan, construction cost and maintenance of civil engineering structures. Apart from the well researched lateritic soils of Nigeria, the black cotton soils (BCS) of north-eastern Nigeria, clay shale of north-western Nigeria, organic clay prominent in Lagos and soft sedimentary deposits of the Niger-Delta areas of Nigeria are also considered. Significant geotechnical properties of major problem soils in Nigeria were discovered to be scattered in different publications, magazines, journals, conference proceedings, research papers etc. Consequently, it is the aim of this paper to collate, correlate, analyze and digitize these important geotechnical properties on digital map of Nigeria. A Geographic Information System (GIS) mapping software called ArcGIS will be used to generate isopleths in form of contours for these soil properties on map of Nigeria.
Geotechnical Properties of Lateritic Soil Stabilized with Banana Leaves Ash
Authors: Nnochiri Emeka Segun , Aderinlewo Olufikayo
Published: June 2020

This paper investigated the geotechnical properties of lateritic soil with banana leaves ash. The natural soil sample was gotten from the Federal University of Technology, Akure (FUTA), Nigeria, and were subjected to preliminary soil tests such as natural moisture content, specific gravity and atterberg limit at its natural state. Engineering tests such as compaction, california bearing ratio and unconfined compressive strength tests  were also carried out on the lateritic soil at their natural states and at when the banana leaves ashes were added to the soil at varying proportions of 2, 4, 6, 8 and 10% by weight of soil. The result of the strength tests showed that the banana leaves ash enhanced the strength of the lateritic soil. The unsoaked CBR value of the soil at its natural state was 10.42 % and it got to optimum value of  28.10% by addition of 4% banana leaves ash by weight of soil. The unconfined compressive strength improved from 209.18 kN/m2  at natural state to 233.77 kN/m 2  at 4% banana leaves ashes. It was therefore concluded that the banana leaves ash satisfactorily act as cheap stabilizing agents for subgrade purposes.
Evaluation of the Effects of Independent Data Assignment (IDA) Method as a mean of Enhancing the Competence of Nigerian Engineering Students
Authors: Fapohunda Christopher , Akinbile Bolatito
Published: June 2020

Understanding basic principles of engineering by students requires practise by hand calculation of simple problems which is usually accomplished through assignments.  This paper reports the results of a method called Independent Data Assignment (IDA) which enables the teacher to generate multi-variables independent data for every student, many times in a teaching period, irrespective of the student population, in such a way that no two students have the same data set for any given assignment, by using the MS-Excel software package. Structural engineering was used as case study. The responses from the questionnaire administered were analysed from which it was found that 91.7% of the students agreed that it helped them in doing independent work and 95% said the method encouraged learning. It can thus be concluded that IDA is an effective tool for effective course delivery, and a model for teachers of courses in engineering with large class
Electricity Cost Aware Virtual Machine Placement Schemes in Distributed Cloud
Authors: Ajibola Opeyemi , Adebusuyi Kehinde , Omoleye Taiwo
Published: June 2020

In recent times, energy efficiency has become an important criterion considered by information and communication technology (ICT) infrastructure providers. This is largely motivated by economic and environmental reasons. By leveraging on technological advancements, it is possible to accomplish desired energy efficiencyimprovementsin the ICT industry. This paper leverages on the virtualization concept (behind the success of cloud computing) and time of usage concept (enabled by smart grid technology) to reduce non-renewable power consumption and total electricity cost of cloud and network infrastructure providers. A mixed integer linear programming (MILP) model was developed to study the impact of varying electricity prices across time zones on the placement of virtual machine (VM) clusters in distributed clouds connected via internet protocol over wavelength division multiplexing (IP over WDM) core network. Results showed that VMclusters are placed at nodes with the cheapest electricity for the three VM cluster placement schemes considered. These results are achieved at the expense of increased non-renewable power consumption and electricity cost in the IP over WDM core network.
Corrosion Of NST60Mn And NST50 Steels Electroplated with Copper in Selected Water Environments
Authors: Ajibola Olawale , Komolafe Daniel , Olorunfemi Bayode
Published: June 2020

Samples of mild carbon (NST50) and medium carbon (NST60Mn) steels were electroplated with copper using acid sulphate bath. Each of the samples was fully immersed into the four media [brine and in some selected water media (rain water, well water, and chlorinated municipal water)] and the corrosion rate (mg/mm2/day) was taken as a measure of degradation at every 2 days interval for 30 days immersion period. By comparison, as-received steel samples have greater levels of corrosion than the copper coated steels in four environments. Cu-coated steel has 3.06x10-3, 6.5x10-4, 5.72x10-4, 3.47x10-4 corrosion rates (mgmm-2day-1) in brine, chlorinated tap water, rainwater, well water respectively.
Groundwater Quality Analysis of Domestic Water Sources from Hand Dug Wells In Gwallameji, Bauchi State
Authors: Ndububa Olufunmilayo I , Ardo Abubakar U
Published: June 2020

Lack of access to safe and adequate domestic water supplies contributes to poverty levels through the economic costs of poor health and the high proportion of household expenditure on safe water supplies. Gwallameji, a community on the outskirts of Bauchi town has no access to municipal water supply from Bauchi town, groundwater water, mainly hand dug wells are used as domestic water sources. The quality of water available from these hand dug wells  in the community were determined by the physical, chemical and biological parameters of the water samples collected from domestic water points in the community. The results from the water samples were compared with World Health Organization (WHO) Standards for Drinking Water. High levels of Nitrate and Chromium above recommended levels from the standard were found in all water samples. Concentrations of Calcium highest value of 213mg/l and Magnesium a highest value of 22.02 mg/l at levels higher than recommended levels for drinking water were also obtained in all samples. It was recommended that restrictions on farming activities with use of fertilizers and location of latrines around domestic water sources should be enforced. Hand dug wells should be at a distance of at least 30m from soak away pits and pit latrines. Well lining and cover should be provided for all hand dug wells to reduce contamination of water from these sources. Increased and continued environmental interventions through public health education by community based health workers, awareness and sensitization campaigns should be carried out for improved household and community sanitation in the area.
Fingerprint Based Approach For Examination Clearance in Higher Institutions
Authors: Saheed Yakub K , Hambali Moshood A , Adeniji Ismaeel A , Kadri Akeem F
Published: June 2020

Biometric techniques have become a prominent option and secured means of authentication capable of sustaining the emerging ubiquitous computing. The process for allowing students to sit for an examination has been through the presentation of medium of identification such as ID cards, library cards, fees clearance cards, photo cards, etc. This method of authenticating a student for an examination has an obvious problem such as presentation of fake clearance card, impersonation and so on.  The unethical manner associated with the examination is a grim issue that require the stakeholders in academic area to seek for alternative means of authenticating student for examination because, the manual paper-based clearance process is fundamentally flawed. This paper addressed all the aforementioned shortcomings and revealed the effectiveness of biometric system using fingerprint for examination clearance. The proposed examination clearance system used fingerprint identification. In identification, the system recognizes an individual by comparing his/her biometrics with every record in the database.
The Effect of Workers Health on Production in Some Selected Quarries in Southwestern Nigeria
Authors: Melodi Mbuyi M
Published: June 2020

The study examined the effect of workers' health on production in some selected quarries in Ondo State, Nigeria. It focuses at accessing the state of labour productivity in quarry operation, the current state of workers' health and identifying the health management facilities available at quarry sites of the study area. Five quarry firms were purposively selected for their high workers enrolment in Ondo State while 14 quarry workers were randomly selected from each quarry; thereby summing up to 70 respondents. Data was collected by means of structured questionnaire to provide information on respondents' personal information, quarry operational activities, availability of health facilities, frequency of clinic visit, and quarry tonnage turn over. Frequency and percentage frequency statistics were the main descriptive statistical tools utilized. While the inferential statistics used are independent sample T -test and Pearson correlation analysis. An analysis of the results established that the quarry workers were mostly males (88.6%) of average age between 20 to 25 years (40.0%); only 6% have a working experience of over 11 years; 32 % have the first degree, the rest have lower certificates; 63% were unmarried. About 80% of the respondents were provided with personal protective equipments and access to first aid facilities. 75.5% attested that quarry companies were working in alliance with health and safety standard (while workers are mostly on 2 shifts (62.9%) per day.  About 13% attested that they have been to clinic twice at the year of this study. Prevalence of ailments among the quarry workers included: head ache (91.4%), malaria (90.0%), catarrh (91.4%), vibration effect (44.3%), dehydration (42.9%), snake and insect bites (31.4%), Silicosis (11.4%) and lung diseases (10%). Monthly tonnage of quarry related strongly (R=0.976) with workers’ population. However, current level of medical facilities had very low correlation with productivity (-0.256). It is recommended that the quarry companies invest in workers’ health services to care for health condition of workers, which in turn have a great and significant implication on daily productivity of each worker.
Production of Ductile Iron from Waste Sleeve Scraps for Automobile Applications
Authors: Adebayo Abdullahi O , Oyetunji Akinlabi
Published: June 2020

There is continuous demand for local production of quality automobile spare parts in the country nowadays. The current economic condition of the nation has placed more challenges on the indigenous foundry to improve on their technology to make automobile spare components accessible and affordable to the nation. This study examined the possibility of converting the indiscriminately dumped sleeve scraps from state of waste to ductile iron useful products thereby adding value to it. The mechanical properties of ductile iron produced from the sleeve scraps using local technology were determined and found comparable to that of international standard (ISO). Sleeve scraps were charged with graphite and FeSi into a rotary furnace and melted. Nodularization was achieved ising MgFeSi as an indigenous technology of the production process. The hypotheses of the study were tested and compared with the ISO standard of the grade of ductile iron and the findings revealed that Ductile iron that corresponds with the standard was successfully produced from solid waste (automobile sleeves scraps). It was recommended among others that the effort be made towards the conversion of sleeve scraps to ductile iron automobile components, in order to minimize the menace of environmental pollution which leads to numerous health hazards and mortality. Also, making automobile spare parts available to the end users and reduce its importation
Construction and Leakage Detection of a Dome-Type Biogas Digester in a Village at Abuja, Nigeria
Authors: Oloche Boniface , Ozigi Idris Ibrahim , Adeyemi Kafayat , Ikpe Elias
Published: June 2020

This work presents construction and leakage detection of dome-type biogas digester. The constructed biogas digester with local materials is rated at 10m3 capacity. The biogas digester foundation, cylindrical wall and dome vault were about 10 cm thick and made of high strength concrete in kilogram at ratio of cement, sharp sand and aggregate of 12 mm size as 111:1:1.2. The constructed biogas digester was pressure tested by using liquid manometer. The pressure gauge level difference of 48 cm (4.7 KN/m2) was obtained, which later dropped to less than 20 cm (1.96 KN/m2)indicating presence of leakage in the biogas digester. Cracks in the biogas digester were located after a careful examination at the cylindrical wall and dome top, which were scaled and sealed with wet cement. The pressure test wasagain conducted and yielded pressure gauge level difference of 60 cm(5.88 KN/m2), without dropping for over 20 minutes, which implies no leakage in the biogas digester.
Statistical Evaluation of Emerging Feature Extraction Techniques for Aging-Invariant Face Recognition Systems
Authors: Oloyede Ayodele , Fagbola Temitayo Matthew , Olabiyisi Stephen , Omidiora Elijah , Oladosu John
Published: June 2020

Large variation in facial appearances of the same individual makes most baseline Aging-Invariant Face Recognition Systems (AI-FRS) suffer from high automatic misclassification of faces. However, some Aging-Invariant Feature Extraction Techniques (AI-FET) for AI-FRS are emerging to help achieve good recognition results when compared to some baseline transformations in conditions with large amount of variations in facial texture and shape. However, the performance results of these AI-FET need to be further investigated statistically to avoid being misled. Statistical significance test can be used to logically justify such performance claims. The statistical significance test would serve as a decision rule to determine the degree of acceptability of the probability to make a wrong decision should such performance claims be found faulty. In this paper, the means between the quantitative results of emerging AI-FET (Histogram of Gradient (HoG), Principal Component Analysis-Linear Discriminant Analysis (PCA-LDA) and Local Binary Pattern-Gabor Wavelet Transform (LBP-GWT)) and the baseline aging-invariant techniques (Local Binary Pattern (LBP) and Gabor Wavelet Transform (GWT)) were computed and compared to determine if those means are statistically significantly different from each other using one-way Analysis of Variance (ANOVA). The ANOVA results obtained at 0.05 critical significance level indicate that the results of the emerging AI-FET techniques are not statistically significantly different from those of baseline techniques because the F-critical value was found to be greater than the value of the calculated F-statistics in all the evaluations conducted.
Screening For Mutations In The Coding Regions Of PSEN1 Gene, 16-17 Exons Of APP Gene And APOE Genotyping In Patients With Alzheimer’s Disease
Authors: KARADUMAN Tugce
Published: June 2020

The aim of this study is to screen for mutations in the presenilin-1 (PSEN1) gene,16-17 exons of amyloid precursor protein (APP) gene and determining apolipoprotein-E (APOE) genotype in patients with Alzheimer’s disease (AD). The coding regions of PSEN1 gene, 16-17 exons of APP gene were screened by using DNA sequence analysis in 30 patients with late onset of Alzheimer’s disease (LOAD) diagnosed based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria and 40 non-dementia controls. Additionally, genotype and allele frequencies of ε2, ε3 and ε4 polymorphisms of APOE gene were determined by using PCR-RFLP methods in both groups. No mutation was found in the coding regions of PSEN1 gene and 16-17 exons of APP gene. On the other hand, rs165932 (G/T) polymorphism was found in intron 8 of PSEN1 in 26 patients. There was no significant difference in genotype and allele frequencies of intronic polymorphism between control group and patients (p>0.05). The frequency of ε3/ε4 genotype was significantly higher in patient group (p<0.05) and frequencies of ε4 allele were also significantly higher among the patients with LOAD (p<0.05). When PSEN1 genotype distribution and ε4 allele frequency were evaluated together in the patient group, no significant relation was found (p>0.05). We suggested that there was a potential association between LOAD and APOE ε4 allele; however, no result could found to link the between PSEN1 gene polymorphism and disease pathogenesis.
Emerging Pharmacotherapy for Covid-19
Authors: Lipworth Brian , Kuo Chris RuiWen , Chan Rory
Published: June 2020

Broadly speaking, pharmacological treatments for COVID-19 can be divided into those acting on upstream pathways early on in the disease process via suppression of viral replication or by inhibiting cell entry, and those acting on downstream pathways later on via selective attenuation of the adaptive immune cytokine-mediated inflammatory response. The antiviral drug remdesivir has been shown to shorten duration of disease while interferon beta-1b may speed up viral clearance. The results with hydroxychloroquine have thus far been rather disappointing. Trials with selective cytokine blockers including anti-interleukin-1 (anti-IL-1) and anti-interleukin-6 (anti-IL-6), have shown some promise in more severe cases, with further confirmation being required from large-scale phase-3 randomised controlled trials. The likelihood is that combination therapy addressing both upstream and downstream pathways may be required to prevent progression of severe COVID-19 infection in susceptible older patients with comorbidities and we believe further studies are now warranted to specifically target such at-risk groups who are more prone to worse outcomes.
“Democracia” em 15 segundos? Estratégias de legitimação do jornalismo contemporâneo
Authors: Schwartz Clarissa , Barichello Eugenia Mariano da Rocha
Published: June 2020

Este artigo tem como objetivo refletir sobre o jornalismo contemporâneo e suas estratégias de legitimação. Buscamos compreender – a partir do contexto teórico da midiatização da sociedade (HJARVARD, 2012) - como são desenvolvidas iniciativas que visam incrementar a participação dos cidadãos nas produções jornalísticas e estimular o exercício da democracia. Como objeto empírico, destacamos o projeto O Brasil que eu quero desenvolvido pela Rede Globo de Televisão em 2018 por conta das eleições presidenciais. Entre os resultados, apontamos que – apesar da proposta ter sido apresentada com a finalidade de dar visibilidade às reivindicações do povo brasileiro - a voz que mais ecoou foi a da organização televisiva que transpôs o modo de produção de notícias centralizado do jornalismo tradicional para o jornalismo em midiatização.
A dança dialética do trabalho em uma cooperativa de jornalistas: o caso do Tiempo Argentino
Authors: Grohmann Rafael
Published: June 2020

O artigo apresenta resultados de investigação no jornal Tiempo Argentino, de Buenos Aires, a partir de entrevistas realizadas em janeiro de 2018, com o objetivo de analisar potencialidades e limites da organização coletiva de trabalho, especialmente “resistências cooperativas”, em contexto de hegemonia da individualização das situações de trabalho. Para tanto, o texto busca contextualizar teoricamente a questão das cooperativas e suas contradições e mapear cooperativas de jornalistas, especialmente, na Argentina. Fundado em 2010, o Tiempo Argentino é gerido por seus trabalhadores desde 2016, em caso de “empresa recuperada por trabalhadores”, com a criação da cooperativa Por Más Tiempo, a iniciativa na área com o maior número de trabalhadores no país.
O discurso religioso da imprensa do interior em tempos de ditadura
Authors: Schmitt Elaine
Published: June 2020

Este artigo dedica-se à análise discursiva, de linha francesa (PÊCHEUX, 2008; ORLANDI, 2010), da produção textual construída pela imprensa de Porto União (SC) e União da Vitória (PR) no primeiro ano da ditadura militar brasileira. A escolha por trabalhar com ambos os jornais, O Comércio e Caiçara, deve-se por estes constituírem o jornalismo escrito da região durante o período, além de entrecruzarem-se e, em certa medida, apresentarem as mesmas formações discursivas. Pretende-se, portanto, refletir sobre os discursos que giram em torno da categoria “religião” a partir, também, de uma perspectiva histórica que leva em conta a construção de acontecimentos na memória social (SAID, 2014). Os resultados apontam para representações já cristalizadas na história social do Brasil, com a utilização de palavras que reativam memórias e anseiam por um mundo onde a crença religiosa é entendida como a salvação necessária.
Democracia e qualidade no jornalismo audiovisual: diálogos TV-Internet e o quinto poder
Authors: Coutinho Iluska Maria da Silva , Mata Jhonatan Alves Pereira , Pereira Gustavo Teixeira de Faria
Published: June 2020

Propostas como a da construção de muros físicos e discursivos e cerceamento das pessoas em relação aos fluxos de informações colocam em xeque os Estados Democráticos e a qualidade do Jornalismo na fiscalização dos poderes Legislativo, Executivo e Judiciário. Assim, o quinto estado, conceito proposto por Willian Dutton (2008), emerge a partir da Internet como fiscalizador da própria imprensa ou quarto poder, e sua atuação é tomada como mote para refletir sobre a qualidade do Jornalismo a partir dos fluxos na web e redes sociais. Para tanto, o texto aborda os conceitos de qualidade no telejornalismo, considerando seu papel de fortalecimento da democracia e dos diálogos estabelecidos entre os fluxos de TV e Internet como formas de (re)estabelecimento do lugar do Jornalismo, com narrativas mais plurais. O artigo buscar realizar uma análise comparada da integração dos conteúdos gerados por usuários nas produções telejornalísticas dos quatro principais canais de TV de Brasil e Espanha, privados e públicos, tomando seus websites como local de coleta, e inferência.
Qualidade no jornalismo: percursos estrangeiros, problemas brasileiros
Authors: Santos Ébida , Guazina Liziane
Published: June 2020

Este artigo tem como proposta mapear e discutir os diferentes entendimentos sobre qualidade no jornalismo. Para isso, considera as perspectivas apresentadas em estudos desenvolvidos em países dos continentes americano e europeu. Dentro da pesquisa, são destacados aspectos relevantes para o debate contemporâneo sobre o jornalismo brasileiro em contexto de riscos à democracia e também são relacionados os métodos e formas de verificação de qualidade propostos por diferentes autores. O artigo divide-se em duas seções, sendo a primeira sobre os estudos norte-americanos e europeus, e a segunda voltada para as discussões latino-americanas. Trata-se de um esforço de revisão sobre como as diferentes abordagens definem e compreendem a noção de qualidade, seus limites e suas possibilidades de aplicação.
O fake é fast? Velocidade, desinformação, qualidade do jornalismo e media literacy
Authors: Prazeres Michelle , Ratier Rodrigo
Published: June 2020

Este artigo pretende evidenciar as relações existentes entre os contextos atuais de hiperinformação, desinformação e infoxicação e o processo de aceleração social do tempo. Buscando compreender as dinâmicas envolvidas no fenômeno das notícias falsas, indica-se uma aproximação entre o fake e o fast no ato comunicativo. A ultravelocidade é vista como vetor privilegiado de produção de uma quantidade de informação superior a que as audiências poderiam processar, gerando espaço para um ecossistema informativo de baixa qualidade marcado pelo consumo irrefletido de notícias. O jornalismo contemporâneo, assim, tende a se afastar do papel social de referência confiável para a tomada de decisões necessárias à vida dos cidadãos e seus semelhantes. Como força de tensão a este movimento, apresentam-se as noções balizantes do jornalismo lento, pautado pela busca da qualidade e da contextualização. Acrescentam-se às práticas comunicacionais da cultura slow os procedimentos de media literacy, possibilitando trabalhar a reflexão e a crítica da informação também no polo da recepção.
Autonomia do jornalista, ética e política editorial: as implicações do enquadramento da notícia
Authors: Rocha Heitor Costa Lima , Alves Anabela Maria Alves Gradim
Published: June 2020

Este trabalho pretende contribuir para o aprofundamento do estado da arte dos estudos de jornalismo, com relação à autonomia do jornalista quanto à política editorial dos veículos, a partir da avaliação das implicações éticas envolvidas na questão epistemológica da guinada linguística/pragmática dos paradigmas científicos tradicional positivista para o construtivista. Neste contexto, são abordadas questões controversas no campo de estudo do jornalismo como o conceito de objetividade e a autoria do jornalista na construção da notícia. Este propósito é perseguido desde os aportes pragmáticos de George Mead e Charles Peirce até as suas continuidades em teorizações mais recentes. A reflexão problematiza o compromisso do jornalismo com a ética da comunicação e uma postura moral pós-convencional fundamentada no compromisso do jornalismo com o fortalecimento da autoridade do público e o empoderamento da cidadania.
Overpricing persistence in experimental asset markets with intrinsic uncertainty
Authors: Sornette Didier , Andraszewicz Sandra , Wu Ke , Murphy Ryan O. , Rindler Philipp , Sanadgol Dorsa
Published: June 2020

To study coordination in complex social systems such as financial markets, the authors introduce a new prediction market set-up that accounts for fundamental uncertainty. Nonetheless, the market is designed so that its total value is known, and thus its rationality can be evaluated. In two experiments, the authors observe that quick consensus emerges early yielding pronounced mispricing, which however does not show the standard “bubble-and-crash”. The set-up is implemented within the xYotta collaborative platform (https://xyotta.com). xYotta’s functionality offers a large number of extensions of various complexity such as running several parallel markets with the same or different users, as well as collaborative project development in which projects undergo the equivalent of an IPO (initial public offering) and whose subsequent trading matches the role of financial markets in determining value. xYotta is thus offered to researchers as an open source software for the broad investigation of complex systems with human participants.
Governance system of the Austrian Medical Chamber
Authors: Kim Hyung-Sun
Published: June 2020

This study aims to improve the organizational system of the Korean Medical Association by comparing its governance to that of the Austrian Medical Chamber. The Austrian Medical Chamber is a legal entity and an interest group, composed of the members of nine provincial Medical Chambers. The composition, authority, and duties of the Austrian Medical Chamber are detailed in the Medical Law, and its publicity as a self-regulatory institution is legally guaranteed, such as health care policy decisions and participation in the justice system. The Austrian Medical Chamber enhances the consistency and connectivity of its work with the provincial Medical Chambers through the obligatory participation of their board members. It allows the provincial Medical Chambers to responsibly perform their duties. The Austrian Medical Chamber and related medical laws can be a role model for the Korean Medical Association to achieve authority as a self-regulatory organization.
Pharmacological management of male sexual dysfunction
Authors: Yang Dae Yul
Published: June 2020

Male sexual disorders, which are the target of clinical treatment, can be largely divided into erectile dysfunction (ED), ejaculation disorder, infertility, sexual desire disorder, hypogonadism, and other diseases related to penile structure changes, such as Peyronieʼs disease. Current approaches to ED treatment for most men are based on pharmacotherapy. Pharmacotherapy has evolved since the introduction of papaverine and phenoxybenzamine in the early 1980s. Sildenafil, a phosphodiesterase type 5 inhibitor (PDE5I), was the first approved drug for ED. Currently, PDE5Is are the most widely prescribed drugs and have an overall efficacy of 60% to 80% in all categories of ED. Most drugs used in ED are peripheral agents that act on the penis. If a combined treatment with a central nervous system agent and peripheral agents is possible, it may be an effective treatment strategy with higher efficacy. Premature ejaculation (PE) is the most frequent ejaculatory disorder. The absence of a consensus on the definition of PE has served as an obstacle in the investigation of its prevalence and the effectiveness of treatment strategies. Although the etiology of PE is unknown, some biological and psychological hypotheses, including anxiety, penile hypersensitivity, and 5-hydroxytryptamine receptor dysfunction have been suggested. Dapoxetine hydrochloride, a short-acting selective serotonin reuptake inhibitor, was approved for on-demand treatment of PE. Off-label use of antidepressants, topical anesthetic agents, tramadol, and PDE5Is is now available as a pharmacological option. The aim of this review is to describe recent advancements in the pharmacological treatment of male sexual disorders, especially focused on ED and PE.
Resonance-enhanced detection of metals in aerosols using single-particle mass spectrometry
Authors: Passig Johannes , Schade Julian , Rosewig Ellen Iva , Irsig Robert , Kröger-Badge Thomas , Czech Hendryk , Sklorz Martin , Streibel Thorsten , Li Lei , Li Xue , Zhou Zhen , Fallgren Henrik , Moldanova Jana , Zimmermann Ralf
Published: June 2020

Abstract. We describe resonance effects in laser desorption–ionization (LDI)
of particles that substantially increase the sensitivity and selectivity to
metals in single-particle mass spectrometry (SPMS). Within the proposed
scenario, resonant light absorption by ablated metal atoms increases their
ionization rate within a single laser pulse. By choosing the appropriate
laser wavelength, the key micronutrients Fe, Zn and Mn can be detected on
individual aerosol particles with considerably improved efficiency. These
ionization enhancements for metals apply to natural dust and anthropogenic
aerosols, both important sources of bioavailable metals to marine
environments. Transferring the results into applications, we show that the
spectrum of our KrF-excimer laser is in resonance with a major absorption
line of iron atoms. To estimate the impact of resonant LDI on the metal
detection efficiency in SPMS applications, we performed a field experiment
on ambient air with two alternately firing excimer lasers of different
wavelengths. Herein, resonant LDI with the KrF-excimer laser (248.3 nm)
revealed iron signatures for many more particles of the same aerosol
ensemble compared to the more common ArF-excimer laser line of 193.3 nm
(nonresonant LDI of iron). Many of the particles that showed iron contents
upon resonant LDI were mixtures of sea salt and organic carbon. For
nonresonant ionization, iron was exclusively detected in particles with a
soot contribution. This suggests that resonant LDI allows a more universal
and secure metal detection in SPMS. Moreover, our field study indicates
relevant atmospheric iron transport by mixed organic particles, a pathway
that might be underestimated in SPMS measurements based on nonresonant LDI.
Our findings show a way to improve the detection and source attribution
capabilities of SPMS for particle-bound metals, a health-relevant aerosol
component and an important source of micronutrients to the surface oceans
affecting marine primary productivity.
A complex aerosol transport event over Europe during the 2017 Storm Ophelia in CAMS forecast systems: analysis and evaluation
Authors: Akritidis Dimitris , Katragkou Eleni , Georgoulias Aristeidis K. , Zanis Prodromos , Kartsios Stergios , Flemming Johannes , Inness Antje , Douros John , Eskes Henk
Published: June 2020

Abstract. In mid-October 2017 Storm Ophelia crossed over western coastal Europe, inducing the combined transport of Saharan dust and Iberian biomass burning aerosols over several European areas. In this study we assess the performance of the Copernicus Atmosphere Monitoring Service (CAMS) forecast systems during this complex aerosol transport event, and the potential benefits that data assimilation and regional models could bring. To this end, CAMS global and regional day-1 forecast data are analyzed and compared against observations from passive (MODIS: Moderate resolution Imaging Spectroradiometer aboard Terra and Aqua) and active (CALIOP/CALIPSO: Cloud-Aerosol Lidar with Orthogonal Polarization aboard Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations) satellites, and ground-based measurements (EMEP: European Monitoring and Evaluation Programme). The analysis of CAMS global forecast indicates that dust and smoke aerosols, discretely located on the warm and cold front of Ophelia, respectively, are affecting the aerosol atmospheric composition over Europe during the passage of the Storm. The observed MODIS Aerosol Optical Depth (AOD) values are satisfactorily reproduced by CAMS global forecast system, with a shared variance of 60 % and a fractional gross error (fge) of 0.4. The comparison with a CAMS global control simulation not including data assimilation, indicates a significant improvement in the bias due to data assimilation implementation, as the fge decreases by 32 %. The qualitative evaluation of the IFS dominant aerosol type and location against the CALIPSO observations reveals a good agreement. Regarding the footprint on air quality, both CAMS global and regional forecast systems are generally able to reproduce the observed signal of increase in surface particulate matter concentrations, with the regional component performing better in terms of bias and temporal variability. Yet, both products exhibit inconsistencies on the quantitative and temporal representation of the observed surface particulate matter enhancements, stressing the need for further development of the air quality forecast systems, for even more accurate and timely support of citizens and policy-makers.