bluuebunny/crossref_metadata_2025 huggingface dataset:
EXPRESSION OF PROTEIN CD73/CD90/CD105/CD34/CD45/CD11b/CD19/HLA-DR ON STEM CELLS FROM HUMAN FAT TISSUE, USING CYTOMETRY FLOW
Authors: Rosadi Imam , Karina Karina , Rosliana Iis , Sobariah Siti , Afini Irsyah , Widyastuti Tias , Barlian Anggraini
Published: February 2020

AbstrakSel punca merupakan sel yang dapat membelah dan berdiferensiasi menjadi sel jenis lainnya. Sel punca asal jaringan lemak potensial dikembangkan sebagai salah satu alternatif sel punca yang bersumber dari limbah sedot lemak manusia. Sel punca asal jaringan lemak akan mengekspresikan protein spesifik penanda permukaan CD73, CD90, CD105 dalam persentase yang tinggi dan CD34/CD45/CD11b/CD19/HLA-DR dalam persentase yang rendah. Studi ini bertujuan untuk memanfaatkan limbah sedot lemak manusia dengan melakukan isolasi sel punca asal jaringan lemak dan menguji protein penanda permukaan spesifik sel punca. Beberapa tahapan dalam studi ini adalah isolasi stromal vascular fraction (SVF) dan kultur sel punca asal jaringan lemak manusia, population doubling time (PDT) serta analisis protein penanda permukaan CD7Ee3, CD90, CD105, dan CD34/CD45/CD11b/CD19/HLA-DR pada pasase ke-1 dari 3 donor. Hasil dari studi ini menunjukkan bahwa sel dari jaringan lemak berhasil dikultur dengan durasi pembelahan sel adalah 3,3 hari. Sel mengekspresikan CD73 (99,79%), CD90 (94,17%), CD105 (48,75%), dan CD34/CD45/CD11b/CD19/HLA-DR (kurang dari 2%). Ekspresi CD105 yang rendah dari ketiga donor diduga berkaitan dengan tingkatan pasase sel yang digunakan. Berdasarkan hasil tersebut dapat disimpulkan bahwa sel punca asal jaringan lemak pasase ke-1 telah mengekspresikan ketiga marker protein penanda permukaan sel punca, yaitu CD73, CD90 dan CD105.Abstract Stem cells are cells that can divide into other different types of similar cells. Stem cells from fat tissue potential have been developed as an alternative stem cell from human liposuction. Stem cells from fat tissue will express high protein-specific markers on CD73, CD90, CD105 and CD34/CD45/CD11b/CD19/HLA-DR in a low percentage. This study aims to utilize human liposuction waste by isolating stem cells from fat tissue and testing protein-specific stem cell surface markers. Some stages in this study are isolation of stromal vascular fraction (SVF) and stem cell culture from human fat tissue, population doubling time (PDT) and protein analysis of surface markers CD73, CD90, CD105, and CD34/CD45/CD11b/CD19/HLA-DR on the 1st passage of 3 donors. The results of this study showed that cells from fat tissue were successfully cultured with cell division duration of 3.3 days. Cells expressed CD73 (99.79%), CD90 (94.17%), CD105 (48.75%), and CD34/CD45/CD11b/CD19/HLA-DR (less than 2%). The low expression of CD105 from all three donors is thought to be related to the level of cell passage used. Based on these results, it can be concluded that the stem cells from first passage fat tissue have expressed the three protein markers of stem cell surface markers, namely CD73, CD90 and CD105.
Стратегічні комунікації у науково-теоретичному дискурсі
Authors: Tereshchenia O.
Published: February 2020

Поняття «стратегічні комунікації» відносно недавно стало популярним у сфері соціальних комунікацій. На початку 2000-х рр. цим терміном послуговувалися переважно у військових, політичних та наукових колах США та деяких європейських країн. Наразі налічується велика кількість досліджень стратегічних комунікацій, це поняття активно починають використовувати в наукових працях та офіційних нормативних документах як у світі, так і в Україні, однак загальноприйнятого визначення того, що являють собою стратегічні комунікації, як цей системний комплекс має студіюватися у спеціальних роботах та що є їх кінцевою метою, допоки не існує. Це породжує певні непорозуміння та дискусії навколо навіть базових складових цього теоретико-практичного феномену. У статті розглянуто існуючі концепції стратегічних комунікацій, основні функції і компоненти поняття, здійснено аналіз окремих міркувань дослідників, запропоновано узагальнене тлумачення терміна. Систематизовано основні підходи до визначення стратегічних комунікацій, виокремлено їхні характеристики. Підкреслено окремі завдання, що необхідно розв’язати під час підготовки ефективної програми стратегічних комунікацій. Визначено, що елементи стратегічних комунікацій складаються з об’єктів стратегії, теорії комунікації та методу. Доведено, що ефективна система стратегічних комунікацій є релевантним показником успішної діяльності організації та реалізації політичної програми, сприяє розвитку інститутів і гарантує підтримку суспільства в кризові моменти. Наголошено на тому, що однією з головних засад стратегічних комунікацій є сприяння реалізації інтересів держави, організації чи компанії, натомість відсутність систематичного підходу, неефективна діяльність головних учасників процесу і нестабільна реалізація організаційних чи політичних стратегічних рішень зменшують вплив механізму організації чи державного управління загалом.
EVALUATION OF EXTRACTS FROM DRY FRUITS BLACK CURRANT (RIBES NIGRUM L.) THROUGH ONE-DIMENSIONAL AND MULTIDIMENSIONAL REGRESSION ANALYSIS FOR PHENOLCARBOXYLIC ACIDS
Authors: Stefanova Radostina , Georgieva Antoaneta , Krastev Krasimir
Published: February 2020

The purpose of the study is to develop a technology for the preparation of blackcurrant extracts. Basic extraction parameters are established. The influence of the technological parameters of the extraction process on the content of phenolcarboxylic acids in the extracts of and currant was analyzed.
The extracts obtained were determined with the amount of phenolcarboxylic acids for use in enriching fruit juices with biologically active substances.
The effect of the type of extractant, the duration and temperature of the extraction and the hydromodule on the color parameters were investigated.
The results of the planned experiment were statistically processed with the Statistica program.
The residuals were estimated and analyzed by normal probability of the residual schedule, the scatterplot of the residuals from the predicted values, and the frequency histogram of the residuals. All results are presented analytically and graphically.
Számítógépes tomográfia és hasűrinyomás-mérés alkalmazása az óriás medián hegsérvek kezelésében
Authors: Fülöp Zsolt Zoltán , Ifj. Bara Tivadar , Simu Patricia , Szilveszter Mónika , Drágus Emőke , Fülöp Réka Linda , Jung János , Bara Tivadar
Published: February 2020

Absztrakt:

Bevezetés: Az óriás hasfali defektusok kezelése kihívást jelent
a sebészek számára. CT-vizsgálattal meghatározható a sérvzsák és a hasüreg
térfogata közötti arány, megállapítva a téraránytalanság mértékét, amely a műtét
utáni hasűri nyomás mértékének kifejezője lehet. Célkitűzés: A
posztoperatív óriás hasfali defektusok kivizsgálásában alkalmazott CT-vizsgálat
jelentőségének alátámasztása, a rekonstrukciós módszer hatékonyságának elemzése
a hasűrinyomás-méréssel. Módszer: Prospektív kutatást végzünk
klinikánkon, vizsgálva az óriás hegsérvvel kezelt betegeinket, akiknél műtét
előtt hasi CT-vizsgálat készül. A hasfal rekonstrukciója feszülésmentesen,
retromuscularisan elhelyezett Prolene hálóval és sérvzsákból készített
peritoneumlebenyekkel történik. Műtét alatt és műtét után hasűri nyomást mérünk,
posztoperatívan 2, 4, 6 hónap után telefonon keresztül követjük betegeinket.
Eredmények: Elért eredményeinket három eset kapcsán
mutatjuk be. 1. eset: A 48 éves nőbetegnél óriás kiújult hegsérv, több
társbetegség állt fenn. Testtömegindexe 43,6, a hasfali defektus átmérője 155
mm, a hegsérv térfogata 1536,63 cm3 volt. A műtét utáni 7. napon
hazabocsátottuk. 2. eset: Az 51 éves férfi betegnél multilocularis óriás hegsérv
keletkezett, testtömegindexe 26,85 volt. A két hasfali defektus átmérője 123 mm
és 105 mm, térfogatuk együttes értéke 406,41 cm3 volt. A műtét utáni
5. napon a beteget elbocsátottuk. 3. eset: A 67 éves férfi beteg testtömegindexe
23,7, a hasfali defektus mérete 100 mm, térfogata 258,10 cm3 volt. A
beteget a műtét utáni 4. napon elbocsátottuk. Következtetés: A
preoperatív CT-vizsgálat adatai fontosak az alkalmazott műtéti technika
megválasztásában. A sérvzsák és a háló együttes alkalmazása az óriás hegsérvek
rekonstrukciójában olcsó és feszülésmentes műtéti technikát biztosít a fokozott
rizikóval rendelkező betegek esetében. A technika rövid távú hatékonyságának
elemzésére a húgyhólyagon keresztül mért hasűri nyomás a választandó módszer.
Orv Hetil. 2020; 161(9): 347–353.
Csípőarthroscopia: rövid távú eredményeink
Authors: Zsákai Zsolt , Gömöri András , Papp Miklós
Published: February 2020

Absztrakt:

Bevezetés: A csípőarthroscopia mint minimálinvazív eljárás egyre
nagyobb szerepet tölt be a csípőízületi megbetegedések diagnosztikájában és
kezelésében. Vizsgálatunkban a csípőarthroscopiának az osztályunkon kialakult
gyakorlatát és az ezzel kapcsolatos kezdeti tapasztalatainkat mutatjuk be.
Célkitűzés: Célunk az volt, hogy osztályunk műtéti
protokolljába illesszük a csípőarthroscopia eljárását, mert az irodalom
áttekintése után, valamint külföldi tanulmányutak tapasztalatát átgondolva
reális és sikeres technikának tartjuk ezt a beavatkozást.
Módszer: Az osztályunkon 2017. 01. 01. és 2019. 04. 15.
között történt 29 csípőarthroscopia eredményeit vizsgáltuk a pre- és
posztoperatív, módosított Harris-csípőpontérték (modified Harris hip score –
mHHS) összehasonlításával. A műtéteket 30 fokos optikával, jellemzően standard
behatolási kapukból végeztük. A műtéti indikáció jellemzően a csípőütközési (hip
impingement) szindróma volt. Eredmények: Izolált ’cam’
(bütyköstengely) típusú deformitást 3, izolált ’pincer’ (csipesz) típusú
deformitást 9, kevert deformitást 13 esetben észleltünk. A 13 férfi és 16 nő
átlagéletkora 44,1 év volt. Legfiatalabb betegünk 22, a legidősebb pedig 60 éves
volt. A műtét után az mHHS szignifikáns javulását észleltük mind az F-, mind a
Student-féle t-próba szerint. Következtetés: A
csípőarthroscopia megfelelő alternatíva a csípő számos betegségének műtéti
kezelésében. A ’learning curve’ (tanulási görbe) hosszabb ugyan, mint más
ízületek tükrözése esetén, a beavatkozás megfelelő szakmai felépítésével azonban
a szövődmények kockázata csökkenthető, ezáltal a csípőarthroscopia megoldás
lehet a csípő számos megbetegedésének ellátásában. Orv Hetil. 2020; 161(9):
340–346.
A Magyarországon végzett első arteria mammaria interna graftolás harmincöt éves coronarographiás utánkövetése
Authors: Péterffy Árpád , Molnár Ferenc , Sipos Dávid , Maros Tamás , Kőszegi Zsolt
Published: February 2020

Absztrakt:

A tünetes koszorúér-betegség kezelésében ma is kiemelkedő szerepet játszanak a
revascularisatiós műtétek (coronary artery bypass grafting – CABG). Az első
beavatkozások elvégzése óta eltelt több mint ötven év alatt számos klinikai
megfigyelés igazolja, hogy a koszorúér-áthidalásra az arteria mammaria interna
(IMA) használható a legkedvezőbb eredménnyel. Az IMA szövettani struktúrája és
élettani tulajdonságai ellenállóvá teszik az eret az érelmeszesedéssel szemben.
Cikkünkben a Magyarországon IMA-graft felhasználásával elsőként végzett
CABG-műtétről emlékezünk meg, egyúttal az IMA kedvező tulajdonságait az
irodalomban eddig közölt leghosszabb (harmincöt éves) utánkövetéses
coronarographia eredményeivel illusztráljuk. Az eset alátámaszthatja azt a
feltételezést is, hogy a mammariagraft prosztaciklintermelése megvédi a
kiáramlási pályát az atherosclerosis progressziójától. Ennek igazolására nagy
esetszámú vizsgálat javasolható, amely sztentimplantációval hasonlítaná össze az
IMA-graft feltételezhető védőhatását a kiáramlási pályán. A hosszú távú követés
során a bal coronaria elülső leszálló ágának (LAD) sztentelését
versus az arteria mammaria interna graftnak a felhelyezését
követően a LAD kiáramlási pályájának alakulását kellene értékelni. Orv Hetil.
2020; 161(9): 354–358.
PENJADWALAN OPTIMAL TIPE PRODUKSI FLOWSHOP DUA TAHAP MENGGUNAKAN METODE BRANCH AND BOUND DENGAN MEMPERHATIKAN WAKTU TRANSPORTASI
Authors: Muhammad Marie , Wulan Elis Ratna
Published: February 2020

Penjadwalan produksi dapat dibagi menjadi dua jenis, yaitu penjadwalan produksi tipe jobshop dan penjadwalan produksi tipe flowshop. Penjadwalan produksi tipe flowshop adalah sebuah penjadwalan sebuah produk yang sedemikian rupa sehingga setiap produk diproduksi melalui mesin yang sama dengan alur produksi yang sama. Terdapat beberapa masalah flowshop, salah satunya adalah dengan memperhatikan waktu transportasi. Dan metode Branch and Bound adalah solusi yang tepat untuk memecahkan masalah penjadwalan produksi dengan memperhatikan waktu transportasi untuk meminimalisir waktu yang terlewati. Pada penulisan Studi Literatur ini, Penjadwalan optimal dari 4 buah job dan 2 buah mesin dengan memperhatikan waktu transportasi adalah 1, 2, 4, dan 3 dengan waktu yang terlewati adalah 59 unit satuan waktu.
Clinical effects of two combinations of olfactory agents on olfactory dysfunction after upper respiratory tract infection during olfactory training
Authors: Qiao Xiao-Feng , Bai Yin-Huan , Wang Guo-Ping , Li Xin , Zheng Wei
Published: February 2020

SUMMARY OBJECTIVE To compare two combinations of olfactory agents for olfactory training therapy of olfactory dysfunction after upper respiratory tract infection (URTI) and investigate the influencing factors on clinical effects. METHODS 125 patients with olfactory dysfunction were randomly divided into two groups: test and control. During the olfactory training, four odors were used in both groups. The olfactory training lasted for 24 weeks. Then, participants were tested using Sniffin’ Sticks and threshold-discrimination-identification (TDI) composite scoring before treatment and at 1, 3, and 6 months after treatment. The TDI scores were compared at different time points between the groups and within them, and influence factors were analyzed. RESULTS There was no significant difference in TDI scores between both groups. Furthermore, TDI scores did not significantly change after one month of treatment in either of the groups. After 3 and 6 months of treatment, TDI scores both significantly increased, and the odor discrimination and identification abilities significantly strengthened in both groups; however, the odor thresholds did not improve. The course of the disease was a significant influencing factor on the therapeutic effect of olfactory training for both groups. CONCLUSION The combination of essential balm, vinegar, alcohol, and rose perfume for olfactory training, which are scents commonly found in daily life, can effectively cure URTI-induced olfactory dysfunction, and significantly improve the odor discrimination and identification abilities. Furthermore, prolonging the treatment time can help with the recovery of olfactory functions, and earlier olfactory training can improve the therapeutic effect.
30 Years of Experience with Non-Hodgkin Lymphoma in Children and Adolescents: a retrospective cohort study
Authors: Oliveira Maria Christina L. , Sampaio Keyla C. , Brito Andrea C. , Campos Marcia K. , Murao Mitiko , Gusmão Rebeca , Fernandes Ana Angélica L. , Viana Marcos B.
Published: February 2020

SUMMARY OBJECTIVE Describe the clinical and demographic characteristics of pediatric patients with non-Hodgkin’s lymphoma (NHL) enrolled in a tertiary unit of Pediatric Hematology between 1982-2015. PATIENTS AND METHODS A retrospective cohort study of 140 patients aged 16 years or less with NHL. Demographic characteristics, data on diagnosis, and outcomes were analyzed. The overall survival (OS) analysis and stratification by the most frequent histological subtypes were performed using the Kaplan-Meier method. RESULTS One hundred and thirty-six patients with de novo NHL and four with NHL as a second malignancy were analyzed. The median age at diagnosis was 6.4 years (interquartile range, 4.2 to 11.1 years); 101 patients were males. Four patients had primary immunodeficiency, four had human immunodeficiency virus, two post-liver transplantation, and one had autoimmune lymphoproliferative syndrome. The most frequent histological type was NHL of mature B- cell (B-NHL-B; 67.1%), with Burkitt’s lymphoma being the most frequent subtype, and lymphoblastic lymphoma (LBL, 21.4%). The main clinical manifestation at the diagnosis was abdominal tumors (41.4%). During the follow-up time, 13 patients relapsed, but five of them reached a second remission. Thirty-five patients died, and 103 remained alive in clinical remission. No contact was possible for two patients. The OS at 5 years was 74.5% (± 3.8%). The OS estimated for patients with LBL, NHL-B, and the remaining was 80.4%±7.9%, 72.8%±4.7%, and 74.5%±11%, respectively (P = 0.58). CONCLUSION Our results are comparable with cohorts from other middle-income countries.
Esophageal manometry in systemic sclerosis: findings and association with clinical manifestations
Authors: Markus Juliana , Pinto Rogério de Melo Costa , Matoso Abadia Gilda Buso , Ranza Roberto
Published: February 2020

SUMMARY INTRODUCTION Systemic sclerosis (SSC) is an autoimmune disorder that affects several organs of unknown etiology, characterized by vascular damage and fibrosis of the skin and organs. Among the organs involved are the esophagus and the lung. OBJECTIVES To relate the profile of changes in esophageal electromanometry (EM), the profile of skin involvement, interstitial pneumopathy (ILD), and esophageal symptoms in SSC patients. METHODS This is an observational, cross-sectional study carried out at the SSC outpatient clinic of the Hospital de Clínicas of the Federal University of Uberlândia. After approval by the Ethics Committee and signed the terms of consent, 50 patients were initially enrolled, from 04/12/2014 to 06/25/2015. They were submitted to the usual investigations according to the clinical picture. The statistical analysis was descriptive in percentage, means, and standard deviation. The Chi-square test was used to evaluate the relationship between EM, high-resolution tomography, and esophageal symptoms. RESULTS 91.9% of the patients had some manometric alterations. 37.8% had involvement of the esophageal body and lower esophageal sphincter. 37.8% had ILD. 24.3% presented the diffuse form of SSC. No association was found between manometric changes and clinical manifestations (cutaneous, pulmonary, and gastrointestinal symptoms). CONCLUSION The present study confirms that esophageal motility alterations detected by EM are frequent in SSC patients, but may not be related to cutaneous extension involvement, the presence of ILD, or the gastrointestinal complaints of patients.
Application value of magnetic resonance hydrography of the inner ear in cochlear implantation
Authors: Wang Peng , Chen Xi , Zhou Hang , Wang Quan , Xue Ju-Jun , Chang Ying-Juan , Lv Xiu-Lin , Wang Na , Sun Chen-Yi , Jiang Hong
Published: February 2020

SUMMARY OBJECTIVE This study aims to investigate the application value of magnetic resonance (MR) hydrography of the inner ear in cochlear implantation. METHODS 146 patients were enrolled. MR hydrography and spiral CT examinations for the intracranial auditory canal were performed before surgery, and all imaging results were statistically analyzed in order to explore the application value of MR hydrography of the inner ear in cochlear implantation. RESULTS 146 patients (292 ears) were examined. Among these patients, 13 were diagnosed with abnormal vestibular aqueducts (20 ears) by MR hydrography, while five were diagnosed with this disease by CT; 15 patients were diagnosed with inner ear malformation (19 ears) by MR hydrography, while 11 were diagnosed by CT (four were misdiagnosed); five patients were diagnosed with internal acoustic canal stenosis (eight ears) by MR hydrography, while two were diagnosed by CT (three were misdiagnosed); and four patients were diagnosed with cochlear fibrosis (five ears) by MR hydrography, while four were diagnosed by CT (four ears). The correct rate of diagnosis was 77.40% (113/146) based on CT, while the rate was 93.84% (137/146) based on MR hydrography. CONCLUSIONS MR hydrography imaging technique can be applied to the preoperative evaluation of cochlear implantation, providing accurate and reliable anatomic information on the inner membranous labyrinth and nerves in the internal acoustic canal and an accurate basis for the diagnosis of cochlear fibrosis and nerve development. This has a guiding significance for the selection of treatment schemes.
Non-alcoholic fatty liver disease in patients infected with human immunodeficiency virus: a systematic review
Authors: Pires Leonardo Bispo , Rocha Raquel , Vargas Daniel , Daltro Carla , Cotrim Helma P
Published: February 2020

SUMMARY OBJECTIVE To evaluate the prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with HIV/AIDS. METHODS The systematic review included articles indexed in MEDLINE (by PubMed), Web of Science, IBECS, and LILACS. Studies eligible included the year of publication, diagnose criteria of NAFLD and HIV, and were published in English, Portuguese, or Spanish from 2006 to 2018. The exclusion criteria were studies with HIV-infection patients and other liver diseases. Two reviewers were involved in the study and applied the same methodology, according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). RESULTS One hundred and sixteen papers were selected, including full articles, editorial letters, and reviews. Twenty-seven articles were excluded because they did meet the inclusion criteria. A total of 89 articles were read, and 13 were considered eligible for this review. Four case series used imaging methods to identify NAFLD, and nine included histology. The prevalence of NAFLD in HIV-patients ranged from 30%-100% and, in nonalcoholic steatohepatitis (NASH), from 20% to 89%. A positive association between dyslipidemia, insulin resistance, and body mass index was observed. There was no agreement between the studies that evaluated the relationship between antiretroviral drugs and NAFLD. CONCLUSION This systematic review showed a high prevalence of NAFLD in HIV-patients, which was associated with metabolic risk factors. The possible association between antiretroviral therapy and NAFLD needs further studies.
Improvement of Faculty’s Skills on the Creation of Items for Progress Testing Through Feedback to Item Writers: a Successful Experience
Authors: Hamamoto Filho Pedro Tadao , Bicudo Angélica Maria
Published: February 2020

Abstract: The evaluation of knowledge is an important step in the teachers’ work, because it is fundamental that the evaluation results be valid and reliable. Several faculty development programs have been undertaken to improve teachers’ skills on item writing. Few studies, however, have explored the benefits of providing feedback to multiple-choice item writers. Progress Testing is a longitudinal assessment of students’ knowledge gain. Their results are useful for generating feedback to students, teachers and medical school managers. The aim of this report is to present a successful experience of faculty development on high-quality item writing for Progress Testing through feedback about the fate of the items written by faculty members. Annually, faculties from medical schools participating in a consortium for the application of the Progress Test are asked to formulate new items to compose the test version. However, the fate of the items is not known by their authors, that is, they do not know if the items are incorporated into the test, if the items have good quality, what is the students’ performance in each of the items, and what is the psychometric function of the items. In 2017, one of the schools participating in the consortium offered its item authors a feedback regarding the flaws in item writing, modification of items by the review committee and students’ performance, as well as psychometric function in each item. The percentage of flawed item (items without enough quality to be selected for the test) was more than 30%. There was an inverse relation between the number of flawed item and the number of items included in the final exam, when analyzing the different content areas of the test (that is, Internal Medicine, Surgery, Pediatrics, Obstetrics and Gynecology, Public Health, and Basic Sciences). In the following year, we observed a decrease in the number of flawed item (less than 10%) and an increase in the number of eligible items to be selected for the Progress Testing. Therefore, giving feedback to item writers seems to be a good strategy for developing the faculty’s ability on writing good quality items.
Análise do Internato em Medicina da Família e Comunidade de uma Universidade Pública de Fortaleza-CE na Perspectiva do Discente
Authors: Lima Ivana Cristina Vieira de , Shibuya Beatriz Yumi Rodrigues , Peixoto Maria das Graças Barbosa , Lima Leilson Lira de , Magalhães Paulo Sávio Fontenele
Published: February 2020

Resumo: Introdução: A atuação do médico de família e comunidade exige um domínio amplo de conhecimentos, habilidades e atitudes para enfrentar a complexidade dos pacientes, da família e da comunidade, com vistas a agir para além da dimensão curativa. Nesse contexto, o internato consiste em uma experiência fundamental para promover a articulação teórico-prática da formação médica. Objetivou-se analisar o internato em Medicina de Família e Comunidade (MFC) de uma universidade pública de Fortaleza-CE, na perspectiva do discente. Métodos: Realizou-se estudo transversal, descritivo, quanti-qualitativo, em agosto e setembro de 2018 com 30 acadêmicos do curso de Medicina do 12º semestre. A coleta de dados foi conduzida por meio de um questionário on-line que avaliou a percepção do acadêmico sobre a preceptoria, a aprendizagem, as aulas teóricas, a estrutura física das unidades, a satisfação geral com o internato e a relação com outros profissionais. Realizaram-se análise descritiva dos dados quantitativos e a análise de conteúdo do tipo temática. Resultados: A maioria dos acadêmicos era do sexo masculino (65,5%) e estava na faixa etária de 22 a 24 anos (55,1%). A satisfação geral com o internato foi considerada como boa (60%) e as aulas teóricas também (63,3%). O aprendizado foi avaliado como bom quanto à: relação médico-paciente e habilidades de comunicação (46,7%); habilidade de registro em prontuário (33,3%); habilidade para realizar atividades coletivas com usuários e equipe multiprofissional (43%). Um total de 73% considerou que o internato contribuiu para a futura atuação profissional na atenção básica. Os aspectos positivos do internato foram: preceptoria; aprendizado acerca da relação médico-paciente; autonomia do discente na condução dos casos; carga horária para estudos; aproximação com a realidade da comunidade; inserção na rotina da unidade; diversidade na aprendizagem; e formação teórico-prática. Por sua vez, destacaram-se como aspectos negativos: infraestrutura da unidade básica de saúde; aprendizagem acerca de ações coletivas e interdisciplinaridade; realização de atividades essenciais; prática baseada em evidências; e preceptoria. Conclusão: De forma geral, o internato em MFC foi bem avaliado pelos discentes, principalmente quanto à preceptoria, ao aprendizado em habilidades clínicas e à contribuição para sua formação médica em uma futura atuação na atenção primária. São necessárias novas pesquisas avaliativas que envolvam a percepção dos preceptores e dos demais profissionais da equipe de saúde, com inclusão da análise da dimensão formativa.
Em tempos de desumanização: a emergência da crítica ontológica no complexo educacional
Authors: Torriglia Patricia Laura , Avila Astrid Baecker , Ortigara Vidalcir
Published: February 2020

Resumo Na atualidade a adaptação ao existente é uma realidade que se impõe, implicando, também, numa necessária compreensão do tempo presente e de uma crítica ontológica que nos permita não só compreender o papel da educação e do conhecimento, senão também costurar estratégias de formação e articulação em que a teoria recupere seu papel fundamental de orientação da prática. Contrariando o espírito do tempo, entendemos que as implicações entre ontologia e conhecimento para o debate da educação apresentam, explícita ou implicitamente, a questão de por que ontologia e por que uma crítica ontológica. Apresentamos neste texto o movimento dialético da dimensão ontológica e gnosiológica a partir de uma concepção de ser humano que possa gerar as possibilidades de interditar a ideia de que o sistema capitalista totalizante não pode ser superado. Ao contrário, é necessário um tipo de conhecimento que considere a totalidade, como nos oferece a ontologia crítica.
Reforma Psiquiátrica e a Dependência Brasileira: entre o arcaico e o moderno
Authors: Alves Daniel Figueiredo de Almeida , Simões Oziris , Carnut Leonardo , Mendes Áquilas
Published: February 2020

Resumo No presente estudo, foram realizadas algumas aproximações da Política de Saúde Mental, como pressuposto da Reforma Psiquiátrica Brasileira (RPB), à luz da Teoria Marxista da Dependência (TMD), com o objetivo de analisar as implicações assistenciais e epidemiológicas desse movimento atrelado à totalidade do processo de acumulação capitalista. Com este intuito, foi abordado do ponto de vista histórico-descritivo os dados de saúde mental na cidade de São Paulo entre 2008 e 2017, promovendo uma análise qualitativa por meio do materialismo histórico-dialético. Demonstrou-se que a RPB é incompleta e hibridiza com diferentes perspectivas de saúde, o que foi constatado pela permanência de características asilares (o arcaico) em conjunto com serviços de caráter substitutivo (o moderno). Dessa maneira, explicita-se a contradição entre dependência e a constituição de uma política social em uma das principais cidades da periferia da economia mundial.
Muertes por homicidio-suicidio en Bogotá
Authors: Coello-Hidalgo Javier Esteban , Tarupi- Montenegro Wilmer Alexander , Téllez-Rodríguez Nelson Ricardo
Published: February 2020

Introducción: las muertes en el contexto del homicidio-suicidio (H-S) son eventos poco frecuentes y por lo tanto poco estudiados en nuestra región. Sin embargo, su estudio ayuda a comprender el escenario de una de las formas más graves de violencia en cuanto niega el derecho humano fundamental a la vida y suprime, en consecuencia, todos los demás derechos. Este estudio describe los casos de H-S sucedidos en el periodo 2007-2012 en Bogotá, mediante su caracterización epidemiológica.

Métodos: los casos de estudio fueron seleccionados a partir de muertes por suicidio que se relacionan con otros fallecidos en los mismos hechos, registrados en el Instituto Nacional de Medicina Legal y Ciencias Forenses de Colombia; se excluyeron aquellos casos en los que uno de los dos, perpetrador o víctima finalmente sobrevivieron a pesar de las lesiones y aquellos en los que el contexto corresponde a pactos suicidas o suicidios dobles. Adicionalmente, se realiza una tipificación de los eventos de H-S estudiados con base en las características sociodemográficas y el contexto de cada evento.

Resultados: se identificaron 25 eventos de H-S, en los que, en su gran mayoría, fueron hombres los perpetradores/suicidas, y mujeres y niños, sus víctimas. El instrumento más utilizado fue un arma de fuego. En el 60% de los casos los eventos ocurrieron en un domicilio y en el 88% de los casos la muerte del perpetrador ocurrió en el mismo lugar donde ocurrió el homicidio. Los factores precipitantes del hecho fueron principalmente sentimientos de amor-celos y la retaliación.

Conclusiones: los eventos de H-S son en su gran mayoría perpetrados por hombres hacia mujeres con quienes mantuvieron algún tipo de relación sentimental, lo que los ubica en contextos de violencia de género. Es importante que las comunidades jurídica y forense visibilicen estos casos de manera que su detección y análisis permita el diseño de estrategias de promoción y prevención que ayuden a disminuir su ocurrencia.
Influencia del conocimiento previo y la repetición de entrevistas
Authors: Peláez-Devesa Miriam , Pérez-Mata Nieves , Diges-Junco Margarita
Published: February 2020

Introducción: en los últimos años han incrementado los casos penales en los que la única prueba con la que se cuenta es la declaración de un menor. Ello ha motivado la búsqueda de factores que puedan afectar a la exactitud y credibilidad de su declaración. El presente estudio se centra en la influencia del conocimiento previo y de la repetición de entrevistas en la memoria y aceptación de la sugestión en una muestra de preescolares.Metodología: veintiséis preescolares participaron en tres sesiones. En la primera sesión, a la mitad de los participantes se les mostró qué es un cuelgabolsos (objeto desconocido), y a la otra mitad se les enseñó cómo se usa y, además, lo manipularon. En las sesiones 2 y 3, se realizaron dos entrevistas y en cada una de ellas se formularon preguntas cerradas sobre acciones reales y falsas, supuestamente llevadas a cabo en la sesión 1.Resultados: los resultados mostraron que el grupo con experiencia proporcionó en general más detalles sobre la acción que había experimentado con el cuelgabolsos en comparación con el grupo sin experiencia; sin embargo, esta diferencia se eliminó en la sesión 3, debido a la repetición de entrevistas. En cuanto a la acción falsa, se encontró efecto techo en la aceptación de la sugestión, y ambos grupos dieron una cantidad similar de detalles en las sesiones 2 y 3.Conclusiones: el conocimiento previo influye en la cantidad de detalles proporcionados únicamente si se pregunta una vez, si las preguntas son repetidas su efecto desaparece.
Aproximación médico-legal al paciente con trastorno facticio
Authors: Hernández-Aragón Fernando , Paz-González Miguel Ángel
Published: February 2020

Introducción: los trastornos facticios son patologías poco comunes y por ello subdiagnosticadas. Es por esto que el personal de salud tiene poca exposición y experiencia en cómo abordar y tratar a este tipo de pacientes. El interés de este artículo es el de presentar un caso y correlacionar la manera como se debe de hacer el manejo de estos pacientes para evitar que el médico entre en problemas legales.Métodos y materiales: el artículo es un reporte de caso que se acompaña de revisión de la literatura. Se encontraron 14 artículos que tenían datos relevantes para la presentación de este tema. Además, se utilizó el Código Penal del Estado de Nuevo León como base en cuanto a la parte legal de este documento.Historia del caso: este caso hace referencia al caso de una mujer de 49 años que presentó un cuadro de debilidad progresiva que no respondía a causa orgánica y que además se agravaba con la presencia de familiares.Resultados y discusión: los trastornos facticios son caracterizados por la invención, producción o falsificación de síntomas tanto físicos como psicológicos que simulan una enfermedad física o mental. El perfil de estos pacientes hace que sea difícil su abordaje. El tratante debe de ser cauteloso con las implicaciones legales que puede conllevar.Conclusiones: los trastornos facticios son poco diagnosticados. La formación de un equipo multidisciplinario es lo más aceptado y a lo que se debe de aspirar.
Evolución de los modelos jurídicos aplicados en la formalización de la propiedad rural, en particular en el proceso de titulación de baldíos rurales en Colombia
Authors: Cabrera Suárez Lizandro Alfonso
Published: February 2020

Objetivo: la presente investigativa realiza un análisis exhaustivo sobre la evolución normativa y jurisprudencial de la titulación de bienes baldíos de carácter rural en Colombia.

Metodología: para esto se han planteado tres objetivos. El primero tiende a identificar y analizar los antecedentes de carácter normativo tanto históricos como vigentes que han regulado el tema de la titulación de bienes baldíos de carácter rural en Colombia; el segundo, identificar y analizar la línea jurisprudencial de la Corte Constitucional en el tema de la titulación de bienes baldíos de carácter rural a partir de la revisión de sentencias de tutela y de constitucionalidad expedidos por dicha corporación; el tercero, analizar lo establecido en la Ley 160 de 1994 y lo consagrado en el Acuerdo Final para la Terminación del Conflicto, en relación con la titulación de baldíos en Colombia. A fin de responder a cada uno se ha planteado un diseño de investigación descriptiva dentro del enfoque de investigación jurídica.

Resultados y conclusiones: aunque en materia de reforma agraria en Colombia se ha intentado pasar de un concepto simple basado en la propiedad de la tierra a uno integral que aborde de manera totalitaria la problemática rural, en la práctica no se ha logrado desarrollar, a pesar de los esfuerzos normativos en la materia.
Modelo de expectativas en torno a la seguridad pública en microempresarios del centro de México
Authors: García Lirios Cruz
Published: February 2020

Objective: to establish the reliability and validity of an instrument that measures expectations of public safety in a context of low local development.Methodology: a non-experimental study was carried out with a non-probabilistic selection of microentrepreneurs, considering their participation in business development and social entrepreneurship programs.Results: three factors related to recruitment, technology and training were established, which accounted for 74% of the total variation.Limitations: Design limits results to the search scenario. Study value: the instrument can be compared with other scenarios and study samples with similar conditions. Conclusions: an exploratory factorial structure was established that will allow its study from the inclusion and contrast of other variables such as quality of life and subjective well-being reported in the literature.
Responsabilidad del Estado colombiano en accidentes de tránsito por el mal estado de las vías
Authors: Cabrera Suárez Lizandro Alfonso
Published: February 2020

Objetivo: el trabajo realiza un análisis de la responsabilidad del Estado en accidentes de tránsito, generada por el mal estado de las vías, a partir de una caracterización del tema de la responsabilidad.

Metodología: con base en una fundamentación teórica y un estado del arte sobre el tema, realiza un escueto estudio desde el derecho comparativo en materia de investigación.

Resultados: finalmente, defiende una posición contraria, en la cual no siempre existe una responsabilidad objetiva de la administración pública.

Conclusiones. entre otras, la sola comprobación del mal estado de las vías no genera responsabilidad del Estado.
Aproximación a una conceptualización de los derechos fundamentales
Authors: Delgado Motoa Beatriz
Published: February 2020

Objetivo: el trabajo se orienta a establecer de forma clara el concepto de los derechos fundamentales, para lo cual toma como base las diferentes corrientes filosóficas que orientan el tema, además de lograr determinarlo en los países que conforman Unasur.

Metodología: estudia cuáles son las diferentes nociones existentes sobre estos derechos y cuáles se consideran fundamentales.

Hallazgos: el mundo, y en especial esta región, ha avanzado de forma considerable en la protección de los derechos fundamentales.

Conclusiones: se presenta la aproximación de un concepto común a todos estos países, a fin de lograr su protección de forma uniforme
Techniques and methods for monitoring the evolution of upper limb fine motor skills
Authors: Guzmán Villamarín Juan David , Guzmán Villamarín Diego Enrique , Rengifo Rodas Carlos Felipe , Londoño Prieto Jerónimo
Published: February 2020

Introduction: This review article is the product of research on the methods, techniques and devices used in the measurement of fine motor skills of upper limbs and its respective evolution, developed at Universidad del Cauca in 2018. Problem: Objective measurement of the evolution of upper limb motor skills in the rehabilitation processes.  Objective: To identify the conventional techniques and electronic devices used in the measurement of the evolution of upper limb motor ability.  Methodology: Four scientific databases were reviewed in addition to the Google Scholar search engine. The keywords used for the search were: "fine motor skills", "hand measurement", "hand rehabilitation"and "hand function", among others.  Results: Approximately 3840 articles related to the subject were found. When applying the exclusion criteria, the article number to be revised was reduced to 63, which were analyzed in the present review. Conclusions: The tools applied by health professionals are convenient due to their rapid execution and easy access, however they can be subject to human error since they depend on the experience of the user. Electronic systems present objective measurements, however, their complexity and cost are high. Originality: This work presents information on the therapeutic techniques and technological devices used, in certain pathologies, for the evaluation of upper limb motor ability. Limitations: Not all articles analyzed have a detailed description of the people in which the studies were conducted.
Studying the Moderating Effect of a Respondent’s Locality in M-commerce Adoption Intention
Authors: Tandon Abhishek , Sharma Himanshu , Aggarwal Anu G.
Published: February 2020

Introduction: The present research was conducted at the University of Delhi in 2018. Problem: With the increase in usage of internet technology through wireless devices, the relevance of m-commerce has amplified. In a developing country like India, the rural and urban population is not equally divided on the use of m-commerce and this demands a detailed study regarding this problem.  Objective: The study aims to determine the factors that influence the m-commerce adoption intention of customers and how the effect varies over rural and urban populations. Methodology: This study combines the TAM and UTAUT model to consider the determinants as perceived ease of use, perceived usefulness, perceived risk, perceived cost, social interaction, and facilitating conditions, taking the endogenous variable as intention to adopt m-commerce.     Results: The results of PLS-SEM accepted the hypotheses underlying the model and also validated the moderating role played by a respondent’s locality over the intention to adopt m-commerce. Conclusion: The proposed model was validated by using PLS-SEM approach on a sample size of 200 collected from the urban and rural areas of Delhi NCR. Moreover, the moderating effect of a respondent’s locality was observed over adoption intention. Originality: With the advancement in technological infrastructure and improvement in mobile data facilities, customers have shown enthusiasm towards making online transactions using their phones. The advantage of mobile commerce over computer based electronic commerce is its mobility. Extant research has shown interest in studying the adoption intention of mobile commerce, based on determinants from the TAM or UTAUT model or their combinations. This study combines both models to choose the determinants of mobile adoption intention.  Limitation: Further studies can be conducted by considering other combinations of determinants and extending the model to incorporate the loyalty measures.
Exploring Relationship Between Tqm and Software Productivity
Authors: Jaiswal Kapil , Garg Minakshi
Published: February 2020

Introduction: This publication is the product of research, carried out in the field of management in year 2018-19, which supports the work of a PhD in Business Management at Chandigarh University.  The purpose of this research is to explore the relation between Total Quality Management (TQM) constructs and productivity in the IT industry. This study has been conducted for organizations operating in the Tricity (Chandigarh, Panchkula and Mohali) and NCR (Noida, Gurgaon and Delhi) regions.
Problem: The control of rising operational costs in any organization has become a challenge and is a major aspect in the sustainability of an organization. Implementation of TQM may reduce these costs by improving productivity in the software development process.
Objective: The objective of the research is to explore if there any relationship exists between TQM and productivity in software development organization and whether TQM positively impacts productivity.
Methodology: The study is based on a descriptive research design. A total of 206 respondents were selected using convenient sampling while 90 responded back on the survey. Exploratory factor Analysis and Multiple Linear Regression techniques were applied to obtain the results.
Results: Out of 4 elements of TQM considered in this study, Customer Focus and Continuous improvement were found to be positively related to productivity while Total Management Commitment was found to not be related to productivity.  The hypothesis related to People Management was abandoned because it was highly correlated to other TQM elements.
Conclusion: TQM positively impacts productivity in software development organizations.
Originality: This study tried to create a causal mathematical model between TQM variables and productivity.
Limitations: Sample size and TQM elements were limited based on availability of time and resources.
Mobile Classroom for Military Tactical Training in Cavalry Mission Planning
Authors: Rojas-Ballesteros Daniel Eduardo , Molina Saldarriaga César Augusto , Palomo Navarro Cristie
Published: February 2020

Introduction: This article is the result of the research project entitled “Mobile classroom for military tactical training in cavalry mission planning, development in the Cavalry school of the Colombian Army from 2010 to 2017”. Its purpose is to identify tools to improve the training process of military personnel. Problem: The training is carried out in a theoretical environment as there is currently no alternative means to training personnel in this field. The present investigation aims to improve the instruction of the army personal with their varying roles and ranks –officers, non-commissioned officers (NCOs) and enlisted soldiers–, when encountering individual and collective training. Objective: Evaluate the impact of the implementation of a mobile classroom equipped with simulation tools, as a strategy for the formation of the members of the Cavalry School. Methodology: Empirical study developed in 5 stages: (i) initial instruction, (ii) diagnostic test, (iii) diagnostic feedback, (iv) performance test and (v) performance evaluation. For this, the adaptation of a trailer, such as a mobile classroom, and the ARMA 3 game was used. Results: The use of the mobile classroom allowed for an increase in the number of trained people whilst reduced training times resulting in lower operating costs and greater sustainability. Conclusion: The implementation of the mobile classroom and the simulation system contributed to the development of skills and abilities, improved decision-making capacities, increased perceptual variation and improved coordination, communication and team decision-making. Originality: First mobile classroom for military training, with invention patent, 10-61804. Limitation: The investigation was carried out at the Cavalry School. The results can only be replicable in other military study centers.