bluuebunny/crossref_metadata_2025 huggingface dataset:
Umbilicaria aprina and U. rhizinata (Umbilicariaceae, lichenized Ascomycota) in Russia
Authors: Davydov Evgeny A. , Yakovchenko Lidiya S. , Kharpukhaeva Tatyana M. , Zheludeva Elena V. , Chesnokov Sergey V. , Konoreva Lyudmila A. , Kuznetsova Ekaterina S. , Storozhenko Yulia V. , Ryzhkova Polina Yu. , Himelbrant Dmitry E.
Published: June 2024

The distribution of Umbilicaria aprina and U. rhizinata in Russia was revised basing on morphological and molecular-phylogenetic data. Umbilicaria aprina is new to Alexandra Land Island (Franz Josef Land Archipelago), Sverdrup Island (Taimyr Dolgano-Nenets District), the republics of Altai, North Ossetia-Alania and Sakha-Yakutia. Umbilicaria rhizinata is new to the republics of Tyva and Buryatia, Putorana Plateau, Kamchatka Peninsula, and the Magadan Region and is therefore reported for the first time to the Asian Subarctic. New localities of the species in other regions are cited. The ITS\5.8S phylogenetic tree supports the distinctness of U. aprina and U. rhizinata. The distribution map is drawn and patterns of distribution of two species are discussed. Umbilicaria aprina occurs in the high Arctic between 74°N and 81°N, whereas the northernmost locality of U. rhizinata is in the vicinity of Norilsk on the Putorana Plateau (ca. 70°N). In mountains U. aprina grows at higher maximal elevations compared to U. rhizinata.
The complete chloroplast genome sequence of Vitis vinifera ‘Krasnostop Zolotovskiy’, an autochthonous variety of the Don Valley
Authors: Sharko Fedor S. , Petrova Kristina O. , Molchanov Nikolay V. , Patrushev Maxim V. , Fedosov Dmitriy Yu. , Toshchakov Stepan V.
Published: June 2024

DNA sequence data from complete chloroplast genomes expand our understanding of plant diversity and contributes to our understanding of evolutionary relationships among species. De novo assembly and annotation of plant chloroplast genomes are difficult due to the high number of repeats and low number of plant chloroplast genomes in international databases. The development of long-read sequencing platforms such as PacBio and Oxford Nanopore, as well as specialized assemblers, is simplifying the process of assembling and annotating large circular molecules. In this work, we report the complete chloroplast genome of the autochthonous Vitis vinifera variety ‘Krasnostop Zolotovskiy’, obtained de novo by the hybrid assembly method using short and long DNA reads. The circular genome of the chloroplast is 160,927 bp long with a GC ratio of 37.38 %. It has four subregions: large single-copy (LSC) region of 71,946 bp, a small single-copy (SSC) region of 36,273 bp, and two inverted repeat regions (IRs) of 26,354 bp each. The chloroplast genome of V. vinifera ‘Krasnostop Zolotovskiy’ harbours 129 genes, comprising 84 protein-coding genes, 8 rRNA genes, and 37 tRNA genes. We also carry out a phylogenetic analysis based on all the complete sequences of grape chloroplast genomes available in the databases, which shows that the V. vinifera ‘Krasnostop Zolotovskiy’ does not have a direct origin with any European variety.
Chara virgata (Charophyceae, Characeae) – new species record for the south of the Far East (the Kurils), unusual stem cortex deformation
Authors: Romanov Roman E. , Glazkova Elena A.
Published: June 2024

Chara virgata Kütz. was found in a sphagnum bog on Urup Island of the Kurils. This is a first species record of charophytes for the Sakhalin Region and new species record for the south of the Far East. The plants have notable deformation of stem cortex at old parts rarely noted for Chara L. and unknown for this species.
A co-design exemplar: how to align with community goals when developing data collection methods with communities from refugee backgrounds
Authors: Gingell Tina , Murray Kate , Correa-Velez Ignacio , Gallegos Danielle
Published: June 2024

Co-design in a research context is an approach that involves participants reflecting on their lived experience of a phenomenon to tailor research outcomes to their needs. It is empowering because it provides greater equity in the research process. However, minimal literature is available on ways to encompass co-design into research planning. This article aims to provide an exemplar of co-design research by describing how data collection methods and tools were developed in a participatory action research project through collaboration with community members with a lived refugee experience in Greater Brisbane, Australia. Eight people (aged 18 to 65) were recruited using convenience and purposive sampling, with four workshops held between January and April 2022. Workshops utilised co-design methods, including journey mapping, personas, brainstorming and experiential learning to capture the lived experience of accessing food, to collaboratively co-design data collection methods and tools, and to train community members as community researchers. Co-designing data collection methods ensured that community members with no research experience could contribute towards the design of culturally appropriate data collection tools. Future research in public health should embed co-design into research/intervention planning, execution and outcomes, and align research goals with community goals by drawing on lived experience.
Lip repositioning using polymethylmethacrylate-based cement and crown lengthening: case report with 12-month follow-up
Authors: Gelesky Ricardo , Borges Jr Ivan , Formiga Márcio
Published: June 2024

Introduction: Excessive gingival display (EGD), often referred to as a gummy smile, ranks among the most common concerns expressed by patients seeking enhanced aesthetic appeal in their smiles. Various treatment modalities are available for addressing this issue, including gingivectomy with or without osteotomy, crown lengthening, botulinum toxin injections, lip repositioning surgery, and orthognathic surgery—often accompanied by orthodontic intervention, contingent upon the underlying cause. A relatively recent addition to this repertoire involves the use of a polymethylmethacrylate-based (PMMA) cement to fill the subnasal depression, aiming to restrict lip movement and reposition the upper lip to reduce gingival exposure. Objective: This article presents a clinical case with a 12-month follow-up, wherein PMMA cement was utilized to address the subnasal depression in conjunction with crown lengthening to resolve EGD in a patient.
Effects of laser and indocyanine-green mediated antimicrobial photodynamic therapy on the red complex bacteria and crevicular procalcitonin level in periodontitis patients: A split-mouth randomized clinical trial
Authors: Arya Anil , Srirangarajan Sridharan , Rao Ravi , Prabhu Srikumar , Deepika Oradiyath
Published: June 2024

Abstract Objective: To determine the effects of laser and photodynamic therapy (PDT) on crevicular procalcitonin (PCT) and red complex bacteria in patients with periodontitis stage II grade A. Methods: Sixty-six sites with periodontitis were selected. After scaling and root planing (SRP), participants were randomized to receive 810-nm diode laser and PDT using indocyanine green (ICG). The primary outcome was the change in crevicular PCT levels and red complex bacterial loads measured using the BAPNA assay. Secondary outcomes included probing depth (PPD), clinical attachment loss (CAL), relative attachment level (RAL), plaque index, and gingival index, assessed at baseline and 3 months post-intervention. Results: Significant improvements (P < 0.001) were observed for all variables within each group at the 3-month follow-up compared to baseline. Among the treatment groups, SRP+ICG-PDT demonstrated a greater reduction in BAPNA and PCT levels compared to SRP+laser and SRP alone. Correlation analysis between BAPNA and PCT revealed a significant positive correlation (r = 0.64; p = 0.001). Conclusion: In patients with periodontitis stage II grade A, a single application of PDT using 810-nm laser and ICG provided enhanced benefits compared to SRP alone or SRP+laser in terms of reducing red complex bacterial load and gingival crevicular procalcitonin levels at the 3-month follow-up.
Efficacy of phthalocyanine dye in antimicrobial debridement by photodynamic therapy as an adjunct to mechanical management of peri-implantitis: an in vitro study
Authors: Yelturi Shramika , Sushma Bolla , Sathwika Pulijala , Chandra Rampalli , Reddy A. Amarender
Published: June 2024

Objective: The aim of the present in vitro study was to evaluate the efficacy of phthalocyanine dye in photodynamic therapy (PDT) as an adjunct to mechanical debridement in the management of peri-implantitis. Methods: S. aureus, F. nucleatum, and P. gingivalis were coated on titanium (Ti) discs and divided into control and test groups. In the control group, mechanical debridement + laser was performed, while in the test group, PDT with hydroxyaluminium phthalocyanine (AIPcOH) dye as photosensitizer was used. Bacterial colony counts and surface hardness were assessed post-operatively. Results: There was a significant difference in the bacterial count reduction at different time intervals in the test group (p=0.01) compared to the control group; no significant difference was observed in surface hardness (p=0.7). Conclusion: This present in vitro study concluded that PDT with AIPcOH dye was effective in eradicating S. aureus, F. nucleatum, and P. gingivalis on Ti discs. This study also concluded that PDT with a photosensitizer can be used as an adjunct in the management of peri-implantitis.
Jonah Goldberg: Suicide of the West: How the Rebirth of tribalism, Populism, Nationalism, and Socialism is Destroying American Democracy
Authors: Třísková Hana
Published: June 2024

Book review on Jonah Goldberg: Suicide of the West: How the Rebirth of Tribalism, Populism, Nationalism, and Socialism Is Destroying American Democracy. Trade paperback edition. New York: Crown Forum, 2020, 455 s.
Politický mýtus, Thomas Robert Malthus a vznik árijské rasové imaginace
Authors: Budil Ivo
Published: June 2024

The emergence of Nazi ideology and the rise of Nazism represented one of the most dramatic and tragic events of modern times, the consequences of which humanity is still dealing with today. The doctrine of the superiority of the Aryan race was an integral part of Nazi doctrine and served as a “scientific” justification for German expansionism and the policy of ethnic genocide. The Nazi conception of the German nation as the chosen Aryan racial community was identified as an example of a modern political myth by Henry Tudor in the early 1970s [Tudor 1972: 16]. We will attempt to explain the rise of Aryan ideology using the concept of political myth and Blumenberg’s notion of “work on myth” as the result of the long development of Western genealogical speculation, which underwent a process of secularization during the Enlightenment and once combined with stimuli coming from contemporary natural sciences, was used under the conditions of modern industrial society to “rationally” legitimize inequalities between people. A parallel development, consisting in the attempt to deny by scientific arguments the equality of human beings, despite the spread of liberal ideas inspired, among others, by the American and French Revolutions, took place in the economic sciences, where the doctrine of the British political economist Thomas Robert Malthus gained prominence at the beginning of the nineteenth century. Malthusianism, Aryan race ideology, Social Darwinism, or the eugenics movement thus had a common denominator, which Friedrich August von Hayek called the “counter-revolution of science” or Zeev Sternhell “counter-Enlightenment”.
The Middle Jurassic (Bajocian–Bathonian) flora of the Tabas Block, central Iran
Authors: Maleki Saeed
Published: June 2024

The present study discusses the outcome of palynlogical and palaeobotanocal investigations of Middle Jurassic strata of the Tabas Block. The most commonly identified spore type is a trilete spore, Klukisporites, which accounts for 30 per cent, and the genus Ischyosporites which makes up 12 per cent of the spore collection. Plant fossils recovered from the borehole studied are indicative of a varied assemblage, starting with a diverse range of ferns and followed by Cycadophytes, Ginkgophytes and Coniferophytes. The predominance of the Lowland group in the Tabas Block during the Bajocian–Bathonian, as indicated by the Sporomorph EcoGroup (SEG) and Plant EcoGroup (PEG) models, suggests that the strata studied were laid down mainly in a lowland environment. Dinoflagellate cysts were found in locations that correspond to river and coastal ecogroups, hinting at marine influence.
GIS cartography. A guide to effective map design (third edition)
Authors: Włodarski Wojciech
Published: June 2024

Book review: GIS cartography. A guide to effective map design (third edition), by Gretchen N. Pethersen, 2021. CRC Press Taylor & Francis Group, Boca Raton/London; 318 pages, Price £31.99, ISBN 978-0-367-85794-3.
Sowiecki dzikus, cuchnący dorsz i Muza – Władysława Chodasiewicza widzenie Petersburga
Authors: Brzykcy Jolanta
Published: June 2024

The aim of this article is to analyze and interpret Vladislav Khodasevich’s poem Petersburg (Петербург, 1925), in which the poet evokes the image of the city during the war communism period from the distance of emigration. The poet presents the city in many dimensions: as a place of struggle for physical survival in an era of crisis caused by the Russian Civil War; as a space where high culture clashed with the barbarism of Bolshevism; and in an autobiographical key – as a time in which his own creative forces flourished. The cityscape is based on a series of antinomies: past – present, tradition – innovation, spirituality – materiality, sacrum – profanum, the real world – the surreal world, the culture of old Russia – the primitivism of new times. This allows us to look at the poem simultaneously from several perspectives: historical-literary (cultural life in St. Petersburg during the Civil War), biographical (the poet’s stay in the city in the years 1920–1922), intertextual (assignment of the poem to the Petersburg text) and metatextual/self-referential (Khodasevich’s aesthetic views).
Wschód czy Zachód? Konflikt (wrogich) narracji w Petersburgu Andrieja Biełego
Authors: Polak Andrzej
Published: June 2024

In this article, Andrei Bely’s novel Petersburg is analyzed in terms of the clash of two hostile narratives – Eastern and Western – that have shaped Russian statehood from the rule of Tsar Peter I. The presence of solutions associated with the West, in the history of Russia, as well as in the social and political system of the Russian state, is considered to be the result of a kind of self-colonization and internal colonization. The author of the article, drawing on terminology developed in post-colonial research, highlights the tensions existing within Russian society at the beginning of the 20th century, which translate into internal divisions in the main characters of the work, in particular the senator Apollon Ableukhov and his son Nikolay. Although they both appear to belong to Western civilization and culture, they in fact pave the way for the victory of a chaos of Eastern provenance, which culminates in the Russian revolutions of the early 20th century.
Wilno mityczne we współczesnej prozie litewskiej
Authors: Peluritytė-Tikuišienė Audinga
Published: June 2024

The myth of the founding of the city of Vilnius became particularly important in Lithuanian art in the decade of the restoration of independence. After a long period of occupation, the capital of Lithuania became not only a catalyst for new formulations of national and civic identity, but also a symbol of freedom. The landscape and architecture of the Old Town of Vilnius embody the archaic Baltic imagination, which is not upstaged but, on the contrary, complemented by the Christian world of Vilnius. The restoration of independence activated the archaic Baltic imagination in Lithuanian art and literature as this kind of imagination had nurtured Lithuanians’ national self-awareness over centuries. This article focuses on two modern Lithuanian prose writers, Antanas Ramonas (1947–1993) and Ričardas Gavelis (1950–2002), whose works evoke the two most striking and different images of the same mythical Vilnius – divine and demonic, hopeful and hopeless. These two opposing images of mythical Vilnius reveal two different viewpoints on the world, on history and on the human being in modern Lithuanian literature.
Reclaiming the feminine in cities at war: female agency, spatial subversion, and linguistic resistance in women-authored literature
Authors: Seidel Anna
Published: June 2024

This article examines the staging and coding of femininity in literary works focused on cities during wartime, authored by women. Drawing on Judith Butler’s reading of Luce Irigaray and Henri Lefebvre’s The production of space, the analysis centers on the works of Lidiya Ginzburg (Zapiski blokadnogo čeloveka, 1984), Anna Świrszczyńska (Budowałam barykadę, 1974), Zlata Filipović (Le journal de Zlata, 1993), and Yevgenia Belorusets (Anfang des Krieges, 2022). The article argues that these texts challenge abstracting, phallogocentric systems of meaning on two distinct planes. First, they subvert abstract spatial structures forced on urban space by masculine power dynamics, accomplishing this through a perspective that emphasizes the city ‘from below’ and underscores the private, as opposed to the institutional, dimension of urban life. Second, they contest the erasure of the feminine in linguistic structures, shedding light on the oppression experienced by women during war and showcasing narrative and linguistic practices that reclaim agency. The article contends that these four texts not only represent deviations from conventional war narratives but also stage their own female authorship as an appeal against phallogocentric linguistic, spatial, and narrative structures. Consequently, they provide a means to articulate the precarity and marginalization of the feminine within both cities during war and economies of significance wherein the female is subjected to obliteration.
Polish cities as a space of history in Boris Khersonsky’s Family archive
Authors: Vorontsova Kristina
Published: June 2024

This article is focused on the so-called urban texts related to Poland with a special emphasis on the historical and geographical region of Galicia, which covers the territories of Red Ruthenia in Ukraine and Lesser Poland, and on their historical connotations as presented in Boris Khersonsky’s book of poetry Family archive (2006). Khersonsky is a Russian-speaking Ukrainian poet from Odesa, who has been awarded prestigious prizes for his literary work both in Ukraine and abroad. Family archive can be described as a sort of novel in verse about the tragic history of the 20th century told through the family history of the author himself. The main goal of this article is to analyze the specific spatial structure of the book in the context of geopoetics and places of memory with a special accent on Polish cities and towns. This territory is the quintessential locus of historical events connected to Eastern European Jewish heritage and the tragedy of the Holocaust. This paper seeks to reconstruct the image of Poland with all the connotations and cultural myths associated with its multicultural experience.
Long-time asymptotic behavior for the Hermitian symmetric space derivative nonlinear Schrödinger equation
Authors: Chen Mingming , Geng Xianguo , Liu Huan
Published: June 2024

Resorting to the spectral analysis of the 4 × 4 matrix spectral problem, we construct a 4 × 4 matrix Riemann–Hilbert problem to solve the initial value problem for the Hermitian symmetric space derivative nonlinear Schrödinger equation. The nonlinear steepest decent method is extended to study the 4 × 4 matrix Riemann–Hilbert problem, from which the various Deift–Zhou contour deformations and the motivation behind them are given. Through some proper transformations between the corresponding Riemann–Hilbert problems, the basic Riemann–Hilbert problem is reduced to a model Riemann–Hilbert problem, by which the long-time asymptotic behavior to the solution of the initial value problem for the Hermitian symmetric space derivative nonlinear Schrödinger equation is obtained with the help of the asymptotic expansion of the parabolic cylinder function and strict error estimates.
Application value of artificial intelligence algorithm-based magnetic resonance multi-sequence imaging in staging diagnosis of cervical cancer
Authors: Chang Rui , Li Ting , Ma Xiaowei
Published: June 2024

The aim of this research is to explore the application value of Deep residual network model (DRN) for deep learning-based multi-sequence magnetic resonance imaging (MRI) in the staging diagnosis of cervical cancer (CC). This research included 90 patients diagnosed with CC between August 2019 and May 2021 at the hospital. After undergoing MRI examination, the clinical staging and surgical pathological staging of patients were conducted. The research then evaluated the results of clinical staging and MRI staging to assess their diagnostic accuracy and correlation. In the staging diagnosis of CC, the feature enhancement layer was added to the DRN model, and the MRI imaging features of CC were used to enhance the image information. The precision, specificity, and sensitivity of the constructed model were analyzed, and then the accuracy of clinical diagnosis staging and MRI staging were compared. As the model constructed DRN in this research was compared with convolutional neural network (CNN) and the classic deep neural network visual geometry group (VGG), the precision was 67.7, 84.9, and 93.6%, respectively. The sensitivity was 70.4, 82.5, and 91.2%, while the specificity was 68.5, 83.8, and 92.2%, respectively. The precision, sensitivity, and specificity of the model were remarkably higher than those of CNN and VGG models (P < 0.05). As the clinical staging and MRI staging of CC were compared, the diagnostic accuracy of MRI was 100%, while that of clinical diagnosis was 83.7%, showing a significant difference between them (P < 0.05). Multi-sequence MRI under intelligent algorithm had a high diagnostic rate for CC staging, deserving a good clinical application value.
Embedded monitoring system and teaching of artificial intelligence online drug component recognition
Authors: Ding Li , Wu Zhengrong , Zhang Junmin , Zhao Quanyi , Chen Xiaoling , Jia Zhong , He Dian
Published: June 2024

Drug testing has many test elements. It aims to prevent unqualified drugs from entering the market and ensure drug safety. The existing artificial intelligence (AI) online monitoring system identifies active ingredients in the process of use. Owing to their openness, data are easy to be lost, failing to meet user needs and inducing a specific impact on the use of the monitoring system. With the continuous development of computer and measurement technologies, various biochemical data are increasing at an unprecedented speed, and numerous databases are emerging. Extracting patterns from considerable known data and experimental facts is an essential task for a wide range of biological and chemical workers. Pattern recognition is one of the essential technologies for data mining. It is widely used in industry, agriculture, national defense, biomedicine, meteorology, astronomy, and other fields. To improve the effect of the online drug ingredient recognition system, this study used AI to design an online drug ingredient recognition-embedded monitoring system and applied AI to the teaching field to improve teaching efficiency. First, this study constructed the framework of the AI online drug ingredient recognition-embedded monitoring system and introduced the process of online drug ingredient recognition. Then, it introduced the pattern recognition method, constructed the pattern recognition system, and presented the pattern recognition algorithm and the algorithm evaluation index. Afterward, it used pattern recognition to conduct a qualitative analysis of the infrared spectrum of drug components and introduced the overall process of the qualitative analysis. In addition, this study employed AI to implement changes to the embedded system instruction in colleges and universities, summarizing the current issues. The impact of drug component recognition and the educational impact of embedded systems were investigated in the experimental portion. The experimental findings demonstrated the excellent accuracy, sensitivity, specificity, and Matthew correlation coefficient of the online drug component recognition-integrated monitoring system in this work. Compared with that of other systems, its average drug component recognition accuracy was above 0.85. Students in five majors reported high levels of satisfaction with the embedded system teaching, which is better for delivering college instruction.
Quantification of C1 inhibitor activity using a chromogenic automated assay: analytical and clinical performances
Authors: Renaudineau Yves , Sailler Laurent , Puissant-Lubrano Bénédicte
Published: June 2024

Objectives

The quantification of functional C1 inhibitor activity (fC1-INH) is an important tool to diagnose bradykinin-mediated angioedema (AE), whether hereditary or acquired. For that an accurate assay is necessary, therefore we evaluated the analytical performances of a fC1-INH chromogenic assay (Berichrom®, Siemens) performed utilizing an Optilite turbidimeter (Binding Site).

Methods

fC1-INH was quantified by means of the chromogenic assay Berichrom®. Internal quality controls were used to determine the precision of the assay. Stability under various storage and matrix conditions, uncertainty, linearity, interference (of hemolysis, lipemia, and icterus), agreement with the manual Technochrom® assay, and diagnostic performances were further evaluated on samples from patients and healthy donors.

Results

The fC1-INH Berichrom® assay presented good performances regarding intra- and inter-assay precision (CV: 1.3–4.5 % and 3.0–6.0 %, respectively), expanded uncertainty (5.5 % at normal level and 12.5 % at the clinical threshold) and linearity (rho2>0.99: range 7–130 % activity). Addition of interfering substances (hemoglobin <16 g/L, intralipid® <12 g/L, and bilirubin <1 g/L) did not affect fC1-INH quantification. fC1-INH activity from healthy donors remained stable in citrate whole blood until 4 days at room temperature, and 7 days when plasma was collected. Agreement between the automated Berichrom® assay and the manual Technochrom® assay (n=47) was excellent as obtained with both quantitative (Deming regression and Bland–Altman difference plot) and qualitative (Kappa index=1) analyses. Finally, the diagnostic performance of the quantification of fC1-INH for AE evaluated on 81 patients revealed a sensitivity of 100 %, a specificity of 97.2 %, a positive predictive value of 83.3 % and a negative predictive value of 100 %.

Conclusions

The automated fC1-INH Berichrom® assay showed good performance, both at the analytical and diagnostic/clinical levels that allowed its usage in a clinical laboratory for C1-INH-dependent bradykinin-mediated AE research in combination with quantitative C1-INH and C4 determinations.
Analytical validation of the amplification refractory mutation system polymerase chain reaction-capillary electrophoresis assay to diagnose spinal muscular atrophy
Authors: Yao Mei , Jiang Liya , Yan Yue , Yu Yicheng , Chen Yuwei , Wang Xiaoyi , Feng Yijie , Cui Yiqin , Zhou Dongming , Gao Feng , Mao Shanshan
Published: June 2024

Objectives

Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by homozygous deletion and compound heterozygous mutations in survival motor neuron 1 (SMN1), with severity tied to the copy number of survival motor neuron 2 (SMN2). This study aimed to develop a rapid and comprehensive method for the diagnosis of SMA.

Methods

A total of 292 children with clinically suspected SMA and 394 family members were detected by the amplification refractory mutation system polymerase chain reaction-capillary electrophoresis (ARMS-PCR-CE) method, which targeted 19 reported mutations, and the results were compared with those in multiplex ligation-dependent probe amplification (MLPA). Individuals with identified point mutations were further confirmed by SMN1 long-range PCR and Sanger sequencing.

Results

A total of 202 children with SMA, 272 carriers, and 212 normal individuals were identified in this study. No difference was found in the R-value distribution of exons 7 and 8 in SMN1 and SMN2 among these cohorts, with coefficients of variation consistently below 0.08. To detect exon 7 and 8 copy numbers in SMN1 and SMN2, the ARMS-PCR-CE results were concordant with those of MLPA. Approximately 4.95 % (10/202) of the study patients had compound heterozygous mutations.

Conclusions

The ARMS-PCR-CE assay is a comprehensive, rapid, and accurate diagnostic method for SMA that simultaneously detects copy numbers of exons 7 and 8 in SMN1/SMN2, as well as 19 point mutations in SMN1 and 2 enhancers in SMN2. This approach can effectively reduce the time frame for diagnosis, facilitating early intervention and preventing birth defects.
ΛΥΣΙΜΕΛΗΣ: Überlegungen zu existenzieller Körperlichkeit und literarischen Strategien von Homer bis Platon
Authors: Kuhn-Treichel Thomas
Published: June 2024

The adjective λυσιμελής (“limb-loosening”) and related statements about bodies dissolving or melting are found in Greek literature in an astonishing variety of contexts, above all in relation to sleep, death and erotic desire. The present paper asks what made the idea of (limbs) loosening so attractive for authors and it traces their use from early Greek epic (Homer and Hesiod) through lyric (Archilochus, Alcman, Sappho, Ibycus, Anacreon and Pindar) to Plato’sPhaedrus. This brings several factors to light: the adjective and related expressions describe existential experiences of loss of control in an embodied way that 1) points to real psychosomatic correlations, 2) contributes to vividness in the sense of ‘embodied cognition’ and often 3) switches between the concrete and the metaphorical, with the latter intensifying the expressive potential especially in lyric. At the same time, a gradual shift can be observed from an integrated concept of the body towards a (conceptual) metaphor. This apparently unremarkable adjective and its related notions thus permit a deep insight into both the cultural ideas and the literary strategies of early and classical Greece.
Solitonic solutions and study of nonlinear wave dynamics in a Murnaghan hyperelastic circular pipe
Authors: Althobaiti Saad
Published: June 2024

This research article delves into the intricate domain of nonlinear wave dynamics within the framework of a Murnaghan hyperelastic circular pipe. Thus, the current study makes use of some powerful analytical approaches to examine the propagation of nonlinear elastic waves on a Murnaghan hyperelastic circular pipe. The work is exceptional since it allows for the incorporation of double dispersion terms and material nonlinearity in the controlling nonlinear mode. The study entails a thorough examination of the propagation and interaction of solitons within the Murnaghan hyperelastic medium, providing insights into the distinctive nonlinear wave phenomena manifested by circular pipe configurations. Theoretical insights are substantiated by numerical simulations, presenting a comprehensive understanding of the dynamic responses within these elastic structures. In the end, graphical representations of some of the derived solutions have been provided for clarification. In addition, the reported solutions in the study help researchers working in modern fields of engineering and materials science to obtain valuable insights that can inform the design, analysis, and optimization of materials and structures in contemporary applications.
„Kapitalerhöhung“
Authors: Schlitt Michael
Published: June 2024

356Kapitalerhöhungen stellen traditionell eines der wichtigsten Instrumente der Unternehmensfinanzierung dar. Der Beitrag beleuchtet die aktuellen Entwicklungen im Kapitalerhöhungsrecht börsennotierter Publikumsgesellschaften im Hinblick auf besonders praxisrelevante Konstellationen, insbesondere unter Berücksichtigung neuer Gesetzgebungsakte wie Zukunftsfinanzierungsgesetz und EU Listing Act sowie einschlägiger aktueller Rechtsprechung. Dabei werden zunächst Bezugsrechtsemissionen, sodann Kapitalerhöhungen mit erleichtertem Bezugsrechtsausschluss und zum Schluss die etwas selteneren, aber dafür komplexeren Sachkapitalerhöhungen in den Blick genommen.
Synthesis of BaO/NiO/rGO nanocomposite for supercapacitor application
Authors: Anisha Nallathambi , Yuvakkumar Rathinam , Ravi Ganesan , Thambidurai Mariyappan , Velauthapillai Dhayalan
Published: June 2024

Considering the global energy crisis, alternative energy resources requirement is rising gradually. In light of dwindling energy resources, we turn to renewable alternatives. Storing this energy for future utilization remains a pressing endeavor. The ideal storage device should possess intensified energy density, power density, and cyclic stability. In this study, we have synthesized metal oxide with carbon based material nanocomposite such as BaO/NiO, BaO/NiO/rGO through cost effective co-precipitation method and their comparative performance for supercapacitor application were studied. Various characterizations were taken for the above synthesized material. X-ray diffraction (XRD) study confirmed the material formation and their crystallinity of the nanocomposite. BaO has tetragonal structure which was confirmed through JCPDS card number 26-0178 and NiO has rhombohedral structure which was confirmed through JCPDS card number 89-7390. To study electrochemical behaviour of electrode material and its cyclic stability, cyclic voltammetry (CV), galvanostatic charge–discharge (GCD) and electrochemical impedance spectroscopy (EIS) studies was executed. BaO/NiO/rGO possesses 1072 F/g specific capacitance at 0.3 A/g in aqueous 1 M KOH. The electrochemical action of hybrid device was setup and it revealed 224 F/g at 0.3 A/g within the charging potential of 1.6 V. Capacitive retention of 97.6 % was achieved by asymmetric hybrid supercapacitor even after 5000 cycles at 10 A/g, this shows prepared nanocomposite exceptional cyclic stability in energy storage application.
THE NATURE AND PROBLEMS OF THE ROYAL PREROGATIVE IN THE ENGLISH LEGAL SYSTEM
Authors: Görgen Nurullah
Published: June 2024

The concept and role of the Royal prerogative in the United Kingdom remain unclear and controversial. Particularly, prerogatives of Charles III, who was newly ascended to the throne, and notable cases such as R (Miller) v The Prime Minister have reignited discussions on the position of prerogatives.
This article explains the concept, position, and functions of prerogatives to underscore their importance in the English legal system, contrary to claims that they are anachronistic and dysfunctional. To achieve this, the article explores traditional and contemporary definitions to comprehend the concept and then address the origin and evolution of prerogatives throughout history, examining the features they possess today because of these changes. This helps classifying them and addressing the limiting factors. Finally, the article demonstrates how ministers, and the monarch are prevented from violating the law when exercising prerogatives. Thus, it asserts the existence of prerogatives will endure within the UK constitution.
Steuerung in Familienunternehmen
Authors: Oesinghaus Andreas , Mostler Jonah , Möller Klaus
Published: June 2024

Familienunternehmen weisen durch ihre finanzielle und emotionale Bindung an eine Familie Besonderheiten auf, die die Ausgestaltung der Steuerungssysteme beeinflussen. Dieser Artikel zeigt entsprechende Wechselwirkungen auf. Dadurch wird eine systematische Grundlage für das Controlling und die Eigentümerfamilie geschaffen, um die jeweiligen Erwartungen an das Steuerungssystem zu artikulieren und abzugleichen.
Steuerung der IT-Sicherheit
Authors: Schallenberg Lasse
Published: June 2024

Die Bewertung bestehender Risiken spielt beim Management von IT-Sicherheit eine bedeutende Rolle und entspricht zugleich auch dem zentralen Problem. Auf Basis dieser Problemstellung werden im Folgenden Empfehlungen für die ganzheitliche Organisation und Steuerung von IT-Sicherheit gegeben, wobei insbesondere die Balanced Scorecard als dafür geeignetes Instrument betrachtet wird.
Digitale Unternehmenssteuerung im Nachhaltigkeitscontrolling
Authors: Stein Patrick
Published: June 2024

Nachhaltigkeit gewinnt im unternehmerischen Umfeld immer mehr an Bedeutung. Dies wird in der Praxis auch einen erheblichen Einfluss auf das Controlling haben. Die erfolgreiche Planung und Implementierung eines steuerungsfähigen Nachhaltigkeitscontrollings kann nur mit einer digitalen Unternehmenssteuerung gelingen. In diesem Beitrag werden dazu Ansätze am Beispiel der Automobilbranche beleuchtet.
Methods for characterization and continuum modeling of inhomogeneous properties of paper and paperboard materials: A review
Authors: Sanjon Cedric W. , Leng Yuchen , Hauptmann Marek , Groche Peter , Majschak Jens-Peter
Published: June 2024

The potential of paper and paperboard as fiber-based materials capable of replacing conventional polymer-based materials has been widely investigated and evaluated. Due to paper’s limited extensibility and inherent heterogeneity, local structural variations lead to unpredictable local mechanical behavior and instability during processing, such as mechanical forming. To gain a deeper understanding of the impact of mechanical behavior and heterogeneity on the paper forming process, the Finite Element Method (FEM) coupled with continuum modeling is being explored as a potential approach to enhance comprehension. To achieve this goal, utilizing experimentally derived material parameters alongside stochastic finite element methods allows for more precise modeling of material behavior, considering the local material properties. This work first introduces the approach of modeling heterogeneity or local material structure within continuum models, such as the Stochastic Finite Element Method (SFEM). A fundamental challenge lies in accurately measuring these local material properties. Experimental investigations are being conducted to numerically simulate mechanical behavior. An overview is provided of experimental methods for material characterization, as found in literature, with a specific focus on measuring local mechanical material structure. By doing so, it enables the characterization of the global material structure and mechanical behavior of paper and paperboard.
Quantitative assessment of occupational radiation exposure in CT: a comparative study using two radiation survey meters for year-long dose monitoring of staff
Authors: Williams Igoniye , Akpabio Ini -Ibeghe , Precious Onuchuku , O.D Ray-offor
Published: June 2024

Introduction: Computed Tomography (CT) is crucial in medical imaging but exposes healthcare workers to ionizing radiation. It is essential to quantify and mitigate occupational radiation exposure. This study provides a comprehensive quantitative analysis of CT settings, using two radiation survey meters, over a year-long monitoring period. Methodology: Healthcare workers operating CT scanners were included. Two radiation survey meters, Meter A (GMC-300E, uSv/h) and Meter B (RAR R311516, uSv/h), were used concurrently for continuous measurement and recording of radiation doses. Statistical analysis compared data from both meters and assessed compliance with regulatory limits and quality assurance standards. Results: The study demonstrated excellent consistency in dose measurements between Meter A and Meter B throughout the year, with no statistically significant discrepancies (p≤; 0.05). Cumulative radiation doses of staff remained within legal limits, indicating the efficacy of current safety measures. Conclusion: The study highlights the reliability of Meter A and Meter B for measuring occupational radiation exposure in CT settings. The convergence of results emphasizes their suitability for healthcare settings requiring precise radiation dose monitoring, enhancing radiation safety in CT scanning and protecting healthcare personnel from ionizing radiation exposure.
Cebolinha
Authors: Pasqualotti Adriano , Bettinelli Luiz Antonio , Bertoni Vanessa Maria
Published: June 2024

Alimentos como frutas e vegetais, considerados fontes importantes de antioxidantes naturais, vêm ganhando cada vez mais destaque entre os consumidores e os pesquisadores (Thaipong et al., 2006). Os efeitos biológicos dos compostos fenólicos em dietas estão relacionados com a atividade anticarcinogênica, antimicrobiana e anti-inflamatória, sendo indicados para o tratamento e a prevenção do câncer, de doenças cardiovasculares e inflamatórias (Scalbert; Williamson, 2000) e como forma terapêutica em doenças metabólicas, endócrinas e nutricionais (Giraldi; Hanazaki, 2010).
Erva-Baleeira
Authors: Borba Tósca Marina , Campani Pizzato Alessandra , Macedo Cuervo Maria Rita , Augustin Schwanke Carla Helena
Published: June 2024

A Varronia curassavica Jacq. é uma espécie de planta heliófita, possui crescimento espontâneo e vigoroso em formato de arbusto perene (Figura 1). É uma planta nativa da Mata Atlântica, que acompanha as áreas abertas da orla do Oceano Atlântico, com ampla distribuição pela faixa litorânea brasileira (Figura 2), além da Argentina e do Paraguai, variando em altitude desde o nível do mar até altas montanhas. Desenvolve-se melhor em clima subtropical e tropical quente e prefere solos arenosos, pouco ácidos e úmidos, florescendo no verão. Apresenta frutos na coloração vermelho-escuro, além de folhas dentadas em cor verde-escuro e flores brancas pequenas reunidas em uma espécie de espiga natural (Figura 3).
Açafrão
Authors: Finger Geisa , Melo Linkievicz Natascha
Published: June 2024

O açafrão é uma especiaria derivada dos pistilos de flores da espécie Crocus sativus, conhecida por características aromáticas e coloríficas, com histórico de efeitos terapêuticos. A flor, de cor lilás, apresenta três estigmas vermelhos unidos na base pelo pistilo de cor amarelada (Figura 1) (Lopresti; Drummond, 2014).
Raiz-Forte
Authors: Stürmer Joselaine , Breda Martins Renata , Baccarin Ianiski Valéria
Published: June 2024

A raiz-forte, planta herbácea perene, tem sido cultivada e usada como um fitoterápico e condimento por, aproximadamente, 2.000 anos (Courter; Rhodes, 1969; Small, 2006). Os primeiros colonos trouxeram a raiz-forte para o continente americano, e a planta tornou-se comum em jardins já no início do século XIX (Frédéric, 2008). A planta chegou ao Brasil pela influência das culturas hebraica e japonesa e hoje pode ser encontrada em feiras e mercados, especialmente na região Sudeste. A raiz-forte tem uma longa história de uso na medicina tradicional, sendo considerada uma das “ervas amargas” consumidas na Páscoa judaica.
Tomilho
Authors: Mazoni Maciel Aline , Abud Drummond Costa Caroline , Rihl Castro Luísa
Published: June 2024

O tomilho é classificado como hortaliça condimentar, e seu uso é empregado desde a Antiguidade para fins medicinais. Suas folhas e flores são utilizadas para consumo como condimento e para extração de óleo essencial (OE) (Donegá et al., 2014). Trata-se de uma planta aromática, bastante utilizada como especiaria culinária, com finalidade de acrescentar sabor às preparações. Timol e carvacrol são os compostos fenólicos predominantes no extrato de tomilho (Del Ré; Jorge, 2012).
Alho
Authors: Garcia Deon Rúbia
Published: June 2024

O alho é uma planta herbácea (Iranshahi, 2012). É constituído por um pseudocaule e um bulbo ou “cabeça do alho”. Esta é formada por bulbilhos, que são folhas escamiformes, mais comumente chamadas de “dentes do alho” (Reis et al., 2014). A coloração da película pode ser branca ou roxa (Lemos Jr.; Lemos, 2011).
Project Spotlight: Large precast concrete girders pose transportation challenge for Vermont bridge project
Authors: Atkinson William
Published: June 2024

The $45 million Rockingham Bridge 24N and 24S project over the Williams River in Rockingham, Vt., was designed to replace the existing bridges with two new structures. JP Carrara & Sons of Middlebury, Vt., was selected as the precasting contractor.
Understanding interpreters' ad hoc knowledge: An empirical study based on English–Chinese simultaneous interpreting
Authors: Li Lan , Chai Mingjiong
Published: June 2024

This study investigates ad hoc knowledge in interpreting – knowledge specifically relevant to an interpreting task, usually acquired by interpreters at pre-service and in-service stages. A quasi-experiment asked eight English–Chinese professional interpreters to prepare for and interpret two speeches with different degrees of specialisation. Five datasets were collected: (1) screen and video recordings of their preparation processes; (2) their responses to a follow-up questionnaire; (3) their scores and answers on a domain knowledge test; (4) their interpreting performance, rated by both professional interpreters and domain experts; (5) the speaker's answers to a few open questions on domain knowledge. Parts of the first and second datasets were used to examine what ad hoc knowledge the interpreters needed; the remaining three datasets, together with recording data from the first, were used to investigate the extent of their need for this knowledge. The findings show that ad hoc knowledge is domain-relevant, yet its scope is highly interpreting-specific, being neither deep nor wide; and it is by nature different from domain knowledge, mainly including speech-relevant expressive knowledge about certain domain(s) and the contextual knowledge interpreters use in their preparation. The implications of these findings for interpreting practice and training are also discussed.
Exploring automatic methods for the construction of multimodal interpreting corpora. How to transcribe linguistic information and identify paralinguistic properties?
Authors: Wang Xiaoman , Wang Binhua
Published: June 2024

In corpus-based interpreting studies, typical challenges exist in the time-consuming and labour-intensive nature of transcribing spoken data and in identifying prosodic properties. This paper addresses these challenges by exploring methods for the automatic compilation of multimodal interpreting corpora, with a focus on English/Chinese Consecutive Interpreting. The results show that: 1) automatic transcription can achieve an accuracy rate of 95.3% in transcribing consecutive interpretations; 2) prosodic properties related to filled pauses, unfilled pauses, articulation rate, and mispronounced words can be automatically extracted using our rule-based programming; 3) mispronounced words can be effectively identified by employing Confidence Measure, with any word having a Confidence Measure lower than 0.321 considered as mispronounced; 4) automatic alignment can be achieved through the utilisation of automatic segmentation, sentence embedding, and alignment techniques. This study contributes to interpreting studies by broadening the empirical understanding of orality, enabling multimodal analyses of interpreting products, and providing a new methodological solution for the construction and utilisation of multimodal interpreting corpora. It also has implications in exploring applicability of new technologies in interpreting studies.