bluuebunny/crossref_metadata_2025 huggingface dataset:
Vaginal delivery report of a healthy neonate born to a convalescent mother with COVID­‐19
Authors: Xiong Xiali , Wei Hong , Zhang Zhihong , Chang Jing , Ma Xiaopeng , Gao Xiang , Chen Qiang , Pang Qiumei
Published: April 2020

The outbreak of the infection of 2019 novel coronavirus disease (COVID­‐19) has become a challenging public health threat worldwide. Limited data are available for pregnant women with COVID‐19 pneumonia. We report a case of a convalescing pregnant woman diagnosed with COVID‐19 infection 37 days before delivery in the third trimester. A live birth without severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection was performed successfully via the vagina. The findings from our case indicate that there is no intrauterine transmission in this woman who developed COVID‐19 pneumonia in late pregnancy.
Prevalence of occult HBV infection in Western countries
Authors: Pisaturo Mariantonietta , Onorato Lorenzo , Russo Antonio , Coppola Nicola
Published: April 2020

Due to a lack of standardized tests, it is difficult to obtain prevalence data and define the real impact of occult HBV infection (OBI) in Western countries. The present review article addresses the prevalence of OBI, defined as presence of hepatitis B virus (HBV) DNA in liver tissue or plasma in HBsAg‐negative subjects, in Western countries. This varies in different studies according to the different methodologies used (based on serology vs virology), to the sample analyzed for the diagnosis (liver tissue vs plasma), to the different populations studied, to the different geographical variations in the HBV spread, to the host characteristics (age, gender, risk factors for acquiring HBV infection) and to the presence of other parenteral infections (hepatitis C virus and/or human immunodeficiency virus [HIV] infections). Considering the different liver diseases analyzed, that is in patients with cryptogenic cirrhosis or advanced liver fibrosis, the prevalence of OBI ranges 4% to 38%. Considering the different populations studied, in the case of parenteral blood exposure it is about 45%, in patients with chronic hepatitis C it is estimated at about 52%, in HIV‐infected patients it ranges from 0% to 45%, in blood donors from 0% to 22.7% and in hemodialysis patients it ranges from 0% to 54%. In conclusion, OBI is a virological entity to be considered when performing the patient's evaluation for immunosuppressive diseases, liver pathologies, or for blood transfusions. Knowing the prevalence and clinical impact of OBI will allow better patient management.
High pATM is Associated With Poor Local Control in Supraglottic Cancer Treated With Radiotherapy
Authors: Bruine de Bruin Leonie , Schuuring Ed , de Bock Geertruida H. , Slagter‐Menkema Lorian , Mastik Mirjam F. , Noordhuis Maartje G. , Langendijk Johannes A. , Kluin Philip M. , van der Laan Bernard F.A.M.
Published: April 2020

Objectives

Most early stage laryngeal squamous cell carcinomas (LSCC) are treated with radiotherapy. Discovery of new biomarkers are needed to improve prediction of outcome after radiotherapy and to identify potential targets for systemic targeted therapy. The ataxia telangiectasia mutated (ATM) gene plays a critical role in DNA damage response induced by ionizing radiation.

Methods

The prognostic value of immunohistochemical expression of pATM, pChk2, and p53 were investigated in 141 patients with T1‐T2 LSCC curatively treated with external beam radiotherapy. Uni‐ and multivariable Cox regression analyses were performed to examine the relation between expression levels of markers and local control.

Results

Local control was significantly worse in cases with high levels of pATM (HR 2.14; 95% CI, 1.08–4.24; P = .03). No significant associations with local control were found for pChk2 and p53 expression. The association of high pATM expression with poor local control was only found for supraglottic LSCC (HR 10.9; 95% CI, 1.40–84.4; P = .02).

Conclusion

Our findings suggest a potential role for ATM in response to radiotherapy in early stage supraglottic LSCC and imply ATM inhibition as a possibility to improve response to radiotherapy.

Level of Evidence

NA Laryngoscope, 130: 1954–1960, 2020
Evaluation of untrustworthy journals: Transition from formal criteria to a complex view
Authors: Kratochvíl Jiří , Plch Lukáš , Sebera Martin , Koriťáková Eva
Published: April 2020

Not all the journals included in credible indices meet the ethical rules of COPE, DOAJ, OASPA, and WAME, and there may also be trustworthy journals excluded from these indices, which means they cannot be used as whitelists for trustworthy journals. Equally, the many methods suggested to determine trustworthiness are not reliable because they include questionable criteria. The question arises whether valid criteria for identifying an untrustworthy journal can be determined and whether other assessment procedures are necessary. Since 2017, the Masaryk University Campus Library has been developing a suitable evaluation method for journals. A list of 19 criteria based on those originally suggested by Beall, COPE, DOAJ, OASPA, and WAME were reduced to 10 objectively verifiable criteria following two workshops with librarians. An evaluation of 259 biomedical journals using both the list of 19 and then 10 criteria revealed that 74 journals may have been incorrectly assessed as untrustworthy using the longer list. The most common reason for failure to comply was in the provision of sufficient editorial information and declaration of article processing charges. However, our investigation revealed that no criteria can reliably identify predatory journals. Therefore, a complex evaluation is needed combining objectively verifiable criteria with analysis of a journal's content and knowledge of the journal's background.
BH organizations seeking billions in emergency funding to avert crisis
Authors: Canady Valerie A.
Published: April 2020

As Congress continues discussions around the development of its fourth economic stimulus package, the mental health and addictions community is pushing forward with a $38.5 billion request in emergency funding to be included in that package to avert a crisis in the delivery of behavioral health treatment.
MH leaders, insurers unite on COVID‐19 resource toolkit
Authors: Canady Valerie A.
Published: April 2020

Observing a need to educate mental health providers and consumers amid a mental health crisis resulting from COVID‐19, several national leaders in the health community have come together to launch a toolkit of free digital resources to help both groups address their mental health needs.
A branch‐and‐cut approach for the least cost influence problem on social networks
Authors: Günneç Dilek , Raghavan S. , Zhang Rui
Published: April 2020

This paper studies a problem in the online targeted marketing setting called the least cost influence problem (LCIP) that is known to be NP‐hard. The goal is to find the minimum total amount of inducements (individuals to target and associated tailored incentives) required to influence a given population. We develop a branch‐and‐cut approach to solve this LCIP on arbitrary graphs. We build upon Günneç et al.'s novel totally unimodular (TU) formulation for the LCIP on trees. The key observation in applying this TU formulation to arbitrary graphs is to enforce an exponential set of inequalities that ensure the influence propagation network is acyclic. We also design several enhancements to the branch‐and‐cut procedure that improve its performance. We provide a large set of computational experiments on real‐world graphs with up to 155 000 nodes and 327 000 edges that demonstrates the efficacy of the branch‐and‐cut approach. This branch‐and‐cut approach finds solutions that are on average 1.87% away from optimality based on a test‐bed of 160 real‐world graph instances. We also develop a heuristic that prioritizes nodes that receive low influence from their peers. This heuristic works particularly well on arbitrary graphs, providing solutions that are on average 1.99% away from optimality. Finally, we observe that partial incentives can result in significant cost savings, over 55% on average, compared to the setting where partial incentives are not allowed.
Effects of network, tunneling, and interphase properties on the operative tunneling resistance in polymer carbon nanotubes (CNTs) nanocomposites
Authors: Zare Yasser , Rhee Kyong Y.
Published: April 2020

Jang‐Yin and Deng‐Zheng equations for electrical conductivity of polymer carbon nanotubes (CNTs) nanocomposites (PCNT) are developed assuming the roles of networked CNTs, interphase, and tunneling regions. The developed models are coupled to formulate the operative resistance of a unit cell (Reff) induced by networked CNTs and tunneling region. The suggested equation is applied to calculate the operative resistance at dissimilar ranges of all parameters. In addition, the experimental measurements of conductivity for some samples are used to examine the predictability of the models. The models correctly predict the conductivity for various samples. Moreover, the parametric analyses demonstrate the sensible impacts of all parameters on the operative resistance justifying the suggested equation. A petite tunneling distance, wide tunnel, and poor polymer tunneling resistivity meaningfully deteriorate the operative resistance.
Cover Image, Volume 76, Issue 5
Authors: Liu Zhenxiu , Zhou Lijuan , Yao Qiang , Liu Yaqian , Bi Xiaoyang , Huang Jiguang
Published: April 2020

The cover image is based on the Research Article Laboratory selection, resistance risk assessment, multi‐resistance, and management of Tetranychus urticae Koch to bifenthrin, bifenazate and cyflumetofen on cowpea by Zhenxiu Liu et al., https://doi.org/10.1002/ps.5723.

image
Correction to: Effectiveness of Topical Insulin Dressings in Management of Diabetic Foot Ulcers
Authors: Bhettani Mehreen K. , Rehman Mubarik , Altaf Humera N. , Altaf Omar S.
Published: April 2020

In the original article, Mehreen K. Bhettani's last name and Mubarik Rehman's first name are misspelled.
Metabolomic changes associated with frontotemporal lobar degeneration syndromes
Authors: Murley Alexander G. , Jones P. Simon , Coyle Gilchrist Ian , Bowns Lucy , Wiggins Julie , Tsvetanov Kamen A. , Rowe James B.
Published: April 2020

Objective

Widespread metabolic changes are seen in neurodegenerative disease and could be used as biomarkers for diagnosis and disease monitoring. They may also reveal disease mechanisms that could be a target for therapy. In this study we looked for blood-based biomarkers in syndromes associated with frontotemporal lobar degeneration.

Methods

Plasma metabolomic profiles were measured from 134 patients with a syndrome associated with frontotemporal lobar degeneration (behavioural variant frontotemporal dementia n = 30, non fluent variant primary progressive aphasia n = 26, progressive supranuclear palsy n = 45, corticobasal syndrome n = 33) and 32 healthy controls.

Results

Forty-nine of 842 metabolites were significantly altered in frontotemporal lobar degeneration syndromes (after false-discovery rate correction for multiple comparisons). These were distributed across a wide range of metabolic pathways including amino acids, energy and carbohydrate, cofactor and vitamin, lipid and nucleotide pathways. The metabolomic profile supported classification between frontotemporal lobar degeneration syndromes and controls with high accuracy (88.1–96.6%) while classification accuracy was lower between the frontotemporal lobar degeneration syndromes (72.1–83.3%). One metabolic profile, comprising a range of different pathways, was consistently identified as a feature of each disease versus controls: the degree to which a patient expressed this metabolomic profile was associated with their subsequent survival (hazard ratio 0.74 [0.59–0.93], p = 0.0018).

Conclusions

The metabolic changes in FTLD are promising diagnostic and prognostic biomarkers. Further work is required to replicate these findings, examine longitudinal change, and test their utility in differentiating between FTLD syndromes that are pathologically distinct but phenotypically similar.
Correction to: Cycloartane triterpenoid (23R, 24E)-23-acetoxymangiferonic acid inhibited proliferation and migration in B16-F10 melanoma via MITF downregulation caused by inhibition of both β-catenin and c-Raf–MEK1–ERK signaling axis
Authors: Kaneda Toshio , Matsumoto Misaki , Sotozono Yayoi , Fukami Satoshi , Nugroho Alfarius Eko , Hirasawa Yusuke , Hamid A Hadi A. , Morita Hiroshi
Published: April 2020

The article Cycloartane triterpenoid (23R, 24E)-23-acetoxymangiferonic acid inhibited proliferation and migration in B16-F10 melanoma via MITF downregulation caused by inhibition of both β-catenin.
Trypanocidal and leishmanicidal activity of six limonoids
Authors: Steverding Dietmar , Sidjui Lazare S. , Ferreira Éden Ramalho , Ngameni Bathelemy , Folefoc Gabriel N. , Mahiou-Leddet Valérie , Ollivier Evelyne , Stephenson G. Richard , Storr Thomas E. , Tyler Kevin M.
Published: April 2020

Six limonoids [kotschyienone A and B (1, 2), 7-deacetylgedunin (3), 7-deacetyl-7-oxogedunin (4), andirobin (5) and methyl angolensate (6)] were investigated for their trypanocidal and leishmanicidal activities using bloodstream forms of Trypanosoma brucei and promastigotes of Leishmania major. Whereas all compounds showed anti-trypanosomal activity, only compounds 1–4 displayed anti-leishmanial activity. The 50% growth inhibition (GI50) values for the trypanocidal and leishmanicidal activity of the compounds ranged between 2.5 and 14.9 μM. Kotschyienone A (1) was found to be the most active compound with a minimal inhibition concentration (MIC) value of 10 μM and GI50 values between 2.5 and 2.9 μM. Only compounds 1 and 3 showed moderate cytotoxicity against HL-60 cells with MIC and GI50 values of 100 μM and 31.5–46.2 μM, respectively. Compound 1 was also found to show activity against intracellular amastigotes of L. major with a GI50 value of 1.5 μM. The results suggest that limonoids have potential as drug candidates for the development of new treatments against trypanosomiasis and leishmaniasis.
Early‐Stage Lithospheric Foundering Beneath the Eastern Tibetan Plateau Revealed by Full‐Wave Pn Tomography
Authors: Bao Xueyang , Shen Yang
Published: April 2020

The west‐east contrast of magmatism in northern Tibet suggests that the lithospheric root has been removed in the west, following continental collision that led to lithospheric thickening and removal, but not in the east where paradoxically larger convergence occurred. Here we show a full‐wave Pn tomography model for the eastern Tibetan Plateau, which reveals a high‐velocity layer beneath the Moho extending to 150‐km depth. The anomalously high velocities and its northward dipping top surface suggest a very depleted and cold mantle consistent with an underthrusted Precambrian Lhasa lithosphere. A high‐velocity column connects this layer to another high‐velocity layer below 190‐km depth, representing early‐stage removal of the Tibetan mantle lithosphere and its interaction with the underthrusted Indian lithosphere. The west‐east contrast is thus attributed to different stages of lithospheric removal, which may be controlled by varying angles of Indian subduction from the west to the east.
Strong‐Motion Seismogeodesy by Deeply Coupling GNSS Receivers with Inertial Measurement Units
Authors: Geng Jianghui , Wen Qiang , Zhang Tisheng , Li Chenghong
Published: April 2020

Global navigation satellite system (GNSS) displacements at near‐source stations can be biased in both amplitude and phase due to fierce earthquake strike. We propose to inject inertial measurement unit (IMU)‐recorded ground motions into GNSS receivers to compensate their phase‐lock loops (PLLs) for seismic motion stress, aiming at keeping steady carrier‐phase tracking. We use a shake table to replay an acceleration record (0.5–2.0 g) from the 2008 Mw7.9 Wenchuan earthquake to test this IMU‐augmented PLL: It achieves a 1.9‐mm amplitude error (RMS) and an 8.0‐ms phase lag against the shake table's recordings, while the conventional PLL languishes to 6.0 mm and 56.5 ms, respectively. Moreover, the IMU‐augmented PLL enables a six‐degree‐of‐freedom integration among the GNSS and IMU data, where the displacement amplitude error and phase lag decline further to 0.9 mm and 3.5 ms, respectively. We believe that the IMU‐augmented GNSS receivers are ideal strong‐motion seismograph to capture trustworthy broadband displacements in the near fields.
Upstream Ultra‐Low Frequency Waves Observed by MESSENGER's Magnetometer: Implications for Particle Acceleration at Mercury's Bow Shock
Authors: Romanelli N. , DiBraccio G. , Gershman D. , Le G. , Mazelle C. , Meziane K. , Boardsen S. , Slavin J. , Raines J. , Glass A. , Espley J.
Published: April 2020

We perform the first statistical analysis of the main properties of waves observed in the 0.05–0.41 Hz frequency range in the Hermean foreshock by the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) Magnetometer. Although we find similar polarization properties to the “30 s” waves observed at the Earth's foreshock, the normalized wave amplitude (δB/|B0|∼0.2) and occurrence rate (∼0.5%) are much smaller. This could be associated with relatively lower backstreaming proton fluxes, the smaller foreshock size and/or less stable solar wind (SW) conditions around Mercury. Furthermore, we estimate that the speed of resonant backstreaming protons in the SW reference frame (likely source for these waves) ranges between 0.95 and 2.6 times the SW speed. The closeness between this range and what is observed at other planetary foreshocks suggests that similar acceleration processes are responsible for this energetic population and might be present in the shocks of exoplanets.
Author Correction: The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss
Authors: Zhang Zhiwei , Hu Yae , Yan Ruhong , Dong Liang , Jiang Yizhi , Zhou Zhichao , Liu Meng , Zhou Tiantian , Dong Ningzheng , Wu Qingyu
Published: April 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: Increased circulating β2-adrenergic receptor autoantibodies are associated with smoking-related emphysema
Authors: Hu Jia-yi , Liu Bei-bei , Du Yi-Peng , Zhang Yuan , Zhang Yi-wei , Zhang You-yi , Xu Ming , He Bei
Published: April 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Inter-patient variations in relative biological effectiveness for cranio-spinal irradiation with protons
Authors: Ytre-Hauge Kristian S. , Fjæra Lars Fredrik , Rørvik Eivind , Dahle Tordis J. , Dale Jon Espen , Pilskog Sara , Stokkevåg Camilla H.
Published: April 2020

Cranio-spinal irradiation (CSI) using protons has dosimetric advantages compared to photons and is expected to reduce risk of adverse effects. The proton relative biological effectiveness (RBE) varies with linear energy transfer (LET), tissue type and dose, but a variable RBE has not replaced the constant RBE of 1.1 in clinical treatment planning. We examined inter-patient variations in RBE for ten proton CSI patients. Variable RBE models were used to obtain RBE and RBE-weighted doses. RBE was quantified in terms of dose weighted organ-mean RBE ($${\overline{{\rm{RBE}}}}_{{\rm{d}}}$$RBE¯d = mean RBE-weighted dose/mean physical dose) and effective RBE of the near maximum dose (D2%), i.e. RBED2% = $${D}_{2 \% ,RBE}/{D}_{2 \% ,phys}$$D2%,RBE/D2%,phys, where subscripts RBE and phys indicate that the D2% is calculated based on an RBE model and the physical dose, respectively. Compared to the median $${\overline{{\rm{RBE}}}}_{{\rm{d}}}$$RBE¯d of the patient population, differences up to 15% were observed for the individual $${\overline{{\rm{RBE}}}}_{{\rm{d}}}$$RBE¯d values found for the thyroid, while more modest variations were seen for the heart (6%), lungs (2%) and brainstem (<1%). Large inter-patient variation in RBE could be correlated to large spread in LET and dose for these organs at risk (OARs). For OARs with small inter-patient variations, the results show that applying a population based RBE in treatment planning may be a step forward compared to using RBE of 1.1. OARs with large inter-patient RBE variations should ideally be selected for patient-specific biological or RBE robustness analysis if the physical doses are close to known dose thresholds.
Chocolate for breakfast prevents circadian desynchrony in experimental models of jet-lag and shift-work
Authors: Escobar Carolina , Espitia-Bautista Estefania , Guzmán-Ruiz Mara A. , Guerrero- Vargas Natalí N. , Hernández-Navarrete Miguel Ángel , Ángeles-Castellanos Manuel , Morales-Pérez Brenda , Buijs Ruud M.
Published: April 2020

Night-workers, transcontinental travelers and individuals that regularly shift their sleep timing, suffer from circadian desynchrony and are at risk to develop metabolic disease, cancer, and mood disorders, among others. Experimental and clinical studies provide evidence that food intake restricted to the normal activity phase is a potent synchronizer for the circadian system and can prevent the detrimental metabolic effects associated with circadian disruption. As an alternative, we hypothesized that a timed piece of chocolate scheduled to the onset of the activity phase may be sufficient stimulus to synchronize circadian rhythms under conditions of shift-work or jet-lag. In Wistar rats, a daily piece of chocolate coupled to the onset of the active phase (breakfast) accelerated re-entrainment in a jet-lag model by setting the activity of the suprachiasmatic nucleus (SCN) to the new cycle. Furthermore, in a rat model of shift-work, a piece of chocolate for breakfast prevented circadian desynchrony, by increasing the amplitude of the day-night c-Fos activation in the SCN. Contrasting, chocolate for dinner prevented re-entrainment in the jet-lag condition and favored circadian desynchrony in the shift-work models. Moreover, chocolate for breakfast resulted in low body weight gain while chocolate for dinner boosted up body weight. Present data evidence the relevance of the timing of a highly caloric and palatable meal for circadian synchrony and metabolic function.
Efficacy of Ultrasound-guided Radiofrequency Ablation of Parathyroid Hyperplasia: Single Session vs. Two-Session for Effect on Hypocalcemia
Authors: Zeng Zeng , Peng Cheng-Zhong , Liu Ji-Bin , Li Yi-Wen , He Hong-Feng , Hu Qiao-Hong , Lin Bo , Shen Xiao-Gang
Published: April 2020

To evaluate safety and efficacy of one- vs. two-session radiofrequency ablation (RFA) of parathyroid hyperplasia for patients with secondary hyperparathyroidism (SHPT) and to compare the outcome of both methods on hypocalcemia. Patients with secondary hyperparathyroidism underwent ultrasound guided RFA of parathyroid hyperplasia. Patients were alternately assigned to either group 1 (n = 28) with RFA of all 4 glands in one session or group 2 (n = 28) with RFA of 2 glands in a first session and other 2 glands in a second session. Serum parathyroid hormone (PTH), calcium, phosphorus and alkaline phosphatase (ALP) values were measured at a series of time points after RFA. RFA parameters, including operation duration and ablation time and hospitalization length and cost, were compared between the two groups. Mean PTH decreased in group 1 from 1865.18 ± 828.93 pg/ml to 145.72 ± 119.27 pg/ml at 1 day after RFA and in group 2 from 2256.64 ± 1021.72 pg/ml to 1388.13 ± 890.15 pg/ml at 1 day after first RFA and to 137.26 ± 107.12 pg/ml at 1 day after second RFA. Group 1’s calcium level decreased to 1.79 ± 0.31 mmol/L at day 1 after RFA and group 2 decreased to 1.89 ± 0.26 mmol/L at day 1 after second session RFA (P < 0.05). Multivariate analysis showed that hypocalcemia was related to serum ALP. Patients with ALP ≥ 566 U/L had lower calcium compared to patients with ALP < 566 U/L up to a month after RFA (P < 0.05). Group 1’s RFA time and hospitalization were shorter and had lower cost compared with Group 2. US-guided RFA of parathyroid hyperplasia is a safe and effective method for treating secondary hyperparathyroidism. Single-session RFA was more cost-effective and resulted in a shorter hospital stay compared to two sessions. However, patients with two-session RFA had less hypocalcemia, especially those with high ALP.
Vertical nanowire III–V MOSFETs with improved high‐frequency gain
Authors: Kilpi O.‐P. , Hellenbrand M. , Svensson J. , Lind E. , Wernersson L.‐E.
Published: April 2020

High‐frequency performance of vertical InAs/InGaAs heterostructure nanowire MOSFETs on Si is demonstrated for the first time for a gate‐last configuration. The device architecture allows highly asymmetric capacitances, which increases the power gain. A device with Lg = 120 nm demonstrates fT = 120 GHz, fmax = 130 GHz and maximum stable gain (MSG) = 14.4 dB at 20 GHz. These metrics demonstrate the state‐of‐the‐art performance of vertical nanowire MOSFETs.
The infection of trematodes on rice frogs (Fejervarya cancrivora)in Karawang Regency, West Java
Authors: Animalesto Gloria
Published: April 2020

Fejervarya cancrivorais often used as raw material for food and export commodities. In 2014, it was recorded that Karawang Regency was the largest producer of frog’s legs meat in West Java. Research on trematode worms ofF. cancrivorafrom Karawang Regency was conducted to find out the diversity of trematodes worms and its infection patterns. The observation was carried out on 120 frogs. The lungs, stomach, intestine, and caecum were examined for trematodes. The results showed that theF. cancrivorainfected by four species of trematodes i.e.,Glypthelminssp.,Pleurogenoidessp.,Haematoloechussp., andDiplodiscussp. with a prevalence of 25.8%, 18.3%, 35.8%, and 23.3%, respectively, and parasite index 1 -25, 1-268, 1-19, and 1-23 individual parasite in each host, respectively.
Unusual call characteristics and acoustic niche adaptation ofLimnonectes larvaepartusIskandar, Evans & Mcguire, 2014 in its habitat (Anura: Dicroglossidae)
Authors: Kurniati Hellen , Hamidy Amir , Clayton Lynn
Published: April 2020

The advertisement call ofLimnonectes larvaepartusis unique among frogs of the genusLimnonecteswhich have a true acoustic organ. The calls of three adult malesL. larvaepartuswere recorded at the foothill of Hutadelita Mountain (N 000 48’ 48.3” E 1220 23’ 00.8”; 396 m asl), Nantu Wildlife Sanctuary, Gorontalo, northern Sulawesi by using an Olympus LS-11 recorder with built-in microphones. Air temperature during recording was around 26°C. Adobe Audition 3.0 software was used to visualize and analyze the calls. The advertisement calls consist of 1-6 pulses, though only one pulse is usually produced. The wave structure of the call ofL. laervaepartusis unusual because it is characterized by a short series of pulses that form a pulse train. Each pulse from the beginning of the call until the middle of the call has its own frequency spectrum, whereas the pulse train during the second half of the call becomes tightly compressed and forms one frequency spectrum. Calls ofL. larvaepartusdo not have a dominant frequency. Minimum frequencies decrease gradually from the beginning to the end of the pulse train; however, the maximum frequency rises gradually. Ascending frequency characters in one pulse also occur in the energy spectrum and bandwidth of frequency. The lowest minimum frequency at the end of pulse train is ~165 Hz; while the highest maximum frequency is also located at the end of the pulse train and is ~6860 Hz. The short pulses call ofL. larvaepertusis similar to that ofL. hasceanus, although the two species are not close relatives; inL. larvaepartus, the pulse only consists of one period, whereas inL. haschenusit consists of two periods. Considering acoustic adaptation, call ofL. larvaepartushas similar frequency spectrum with call ofL. modestus, we assume that they would not call at the same time and at the same localities because of their similar acoustic niches.
The invasive apple snail Pomacea canaliculata in Indonesia: a case study in Lake Rawa Pening, Central Java
Authors: Marwoto Ristiyanti M. , Heryanto Heryanto , Joshi Ravindra C.
Published: April 2020

The occurrence of the invasive apple snail Pomacea canaliculata in Indonesia was first reported in 1984. The species was introduced as an ornamental aquarium pet. Since then, people have begun to culture the snail in ponds usually adjacent to rice fields. When it was realized that the species multiplied rapidly and was a serious pest, this invasive apple snail had already spread widely. There are many cultural methods of controlling and preventing its distribution, but none are effective in keeping them at non-damaging levels. We mapped the distribution of P. canaliculata in Indonesia from the MZB’s collections as well as literature references and found that the snail invaded almost all large islands, such as Sumatra, Java, Kalimantan, Sulawesi, Maluku, and West Papua. We also studied the impact of P. canaliculata on the native apple snails P. ampullacea, P. scutata, and P. virescens in Lake Rawa Pening (a popular tourism destination) as a case study. The results showed that two species of Pila already disappeared from Lake Rawa Pening. Only P. scutata occurs still in the region and was found alive usually in shallow water and rice fields surrounding the lake. To resolve the problem we recommend that cleaning the lake periodically from the invasive aquatic weed Eichhornia crassipes (known to locals as “eceng gondok”) by a private company and harvesting the weeds for the local small craft industry by the local fishermen could be an alternative measure to reduce the population of the P. canaliculata, as well as collecting P. canaliculata for local food or for feeding ducks. Rearranging the number of fish-pens “karamba” and their location in the lake could be seen as an alternative way also for reducing the population of P. canaliculata, since the snails lay their egg masses on the bamboo stakes of “karamba.” Such rearrangement could make the landscape more attractive for tourism.
Invasive toads are close to but absent from Komodo National Park
Authors: Kennedi Umar F , Kusrini Mirza D , Ariefiandy Achmad , Mardiastuti Ani
Published: April 2020

The islands of Komodo National Park in the Wallacea region are the habitats of Komodo dragon (Varanus komodoensis). Although the Wallacea islands have lower species richness compared to the other large islands in Indonesia, they are rich in endemics, and the occurrence of invasive species would therefore threatened the ecological, economic and social balance of the regions. Several papers have hinted at the possibility of the invasion of Komodo National Parks by Asian toads, a situation which would potentially affect the survival of the Komodo dragon. To detect the presence of the invansive toad Duttaphrynus melanostictus in Komodo National Park and its surroundings areas we carried out an amphibian survey using a Visual Encounter Survey method during February to April 2018. The surveyed location consisted of two main islands within Komodo National Park (Rinca island and Komodo island), Flores island (Labuan Bajo and Cumbi village) and Sumbawa island (Sape). Two species of amphibians were found in Komodo National Park (Rinca island and Komodo island), while seven species of amphibians were found across all four locations. No D. melanostictus toads were found in Flores (including in Komodo National Park), however the toad was found to be abundant in Sape (Sumbawa island).
Freshwater fishes of Pulosari mountain areas in Pandeglang Regency, Indonesia
Authors: Haryono Haryono
Published: April 2020

Indonesia has many freshwater fish species but not recorded with completely, one of them from Banten Province especially in Pulosari Mountain areas of Pandeglang Regency. This study aimed to assess fish diversity, abundance, local distribution, potency, species status, bioecology aspects, and habitat condition. The study was conducted in September 2015 using survey methods. The site study was divided in five stations, the fishing gear mainly electrofishing and completed by cast net with diameter 2.5 meter. The operational of fishing gears using CPUE (catch per unit of efforts). Fish sample counted based on number of species and number of individuals for each species, then preserved and identified. Specimens were deposited in the Museum Zoologicum Bogoriense (MZB) Cibinong. The results recorded 12 species belonging to 11 families. St.2 (Cilagra river) is the most diverse with 8 species, following St.4 (Cijeruk lower) with 7 species.Barbodes binotatusis the most dominant species (19.2 ind./St.) and also widespread (100%). Two introduce species were found i.e.Poecillia reticulataandOreochromis niloticus. Based on potency almost balance both consume and ornamental fish. The inland waters in these areas were suitable for fish habitat.
La pratique du théâtre-forum pour la formation à la relation en santé. Une expérience exploratoire
Authors: Bellanger William , Saint Cricq Emmanuelle , Fayolle Anne-Victoire , Texier-Legendre Gaëlle , Guelff Jessica , Cade Charline
Published: April 2020

Contexte :  Apprendre à communiquer avec les patients pour favoriser la relation est un objectif de formation du deuxième cycle des études médicales en France. Des séances inspirées du théâtre-forum d’Augusto Boal pourraient permettre le développement contextualisé de cette compétence professionnelle.But :Évaluer l’intérêt du théâtre-forum pour la formation des étudiants en médecine à la communication et la relation médecin-patient.Méthodes :Depuis 2014, les étudiants en quatrième année de médecine ont participé à des séances d’enseignement inspirées du théâtre-forum. Des situations potentiellement difficiles entre médecin et patient ont été jouées par des comédiens, puis les étudiants ont été invités à intervenir successivement pour proposer des alternatives possibles. Des questionnaires ont été distribués aux étudiants afin d’évaluer ce dispositif. Le critère de jugement principal quantitatif était la note attribuée à l’enseignement. Les critères qualitatifs exploraient les réactions et ressentis des étudiants.Résultats :Sur 776 questionnaires distribués, 688 ont été analysés. Les étudiants ont attribué une note moyenne de 7,79/10 à cet enseignement. Plus de 80 % d’entre eux ont estimé avoir été sensibilisés aux objectifs pédagogiques d’annonce de maladie grave et de relation-communication avec les patients. Le caractère pratique et le réalisme de l’enseignement ont été les principaux avantages cités par les étudiants. Ils ont également apprécié son caractère réflexif. Cependant, la présence d’un public a représenté une difficulté pour certains.Conclusion :Le théâtre-forum semble un dispositif pédagogique innovant apprécié des étudiants et utile pour les sensibiliser à la communication dans la relation médecin-patient.
Highly Regioselective Synthesis of 3,5-Substituted Pyrazoles from Bromovinyl Acetals and N-Tosylhydrazones
Authors: Phansavath Phannarath , Ratovelomanana-Vidal Virginie , Westermeyer Anne , Llopis Quentin , Guillamot Gérard
Published: April 2020

A regioselective synthesis of 3,5-disubstituted pyrazoles was achieved by 1,3-dipolar cycloaddition of diazo compounds, generated in situ from N-tosylhydrazones, with unactivated bromovinyl acetals, which served as alkyne surrogates. The reaction tolerated N-tosylhydrazones bearing various substituted benzylidene groups, and a range of 3,5-disubstituted pyrazoles were obtained in yields of up to 92%.
Tidal Breathing Parameters Measured by Structured Light Plethysmography in Newborns: Is It Feasible in Neonatal Intensive Care Unit?
Authors: Dizdar Evrim Alyamac , Bozkaya Davut , Sari Fatma Nur , Beser Esra , Tayman Cuneyt , Oguz Serife Suna
Published: April 2020

Objective Structured light plethysmography (SLP) is a novel and noncontact respiratory assessment technique. It provides tidal breathing measurement in patients difficult to cooperate. In this study, we aimed to determine data for tidal breathing parameters measured by SLP in newborns.

Study Design Infants between 2 and 5 days of life without having any respiratory symptoms were eligible for this observational study. In total, 5 minutes of tidal breathing was recorded using SLP (Thora-3Di, PneumaCare Ltd, Cambridge, U.K.) in each infant. Various tidal breathing parameters including timing indices, flow-based parameters, and regional parameters were obtained from SLP data.

Results A total of 57 infants underwent measurements in the study. Evaluable recordings from 42 term and 11 late preterm infants were analyzed. Median gestational age and birthweight of the infants were 38 (37–39) weeks and 3,195 (2,790–3,585) g, respectively. In terms of flow-based parameters, “tidal inspiratory flow at 50% of inspiratory volume divided by tidal expiratory flow at 50% of expiratory volume” was 1.29 (1.13–1.53). Relative contribution of the thorax to each breath in percentage was measured as 38.67 (28.21–43.60). Median values of left–right hemithoracic asynchrony and thoraco-abdominal asynchrony were 6.92 (5.35–9.04) and 17.96 (12.98–36.44) degrees in the study population, respectively. There were no differences in tidal breathing parameters except “hemithoracic asynchrony” between term and late preterm infants. Hemithoracic asynchrony was significantly lower in term neonates than late preterms.

Conclusion SLP was found to be feasible to obtain measures of tidal breathing parameters in newborns and it could be performed successfully even in the first days of life.
Entanglement manipulation beyond local operations and classical communication
Authors: Chitambar Eric , de Vicente Julio I. , Girard Mark W. , Gour Gilad
Published: April 2020

When a quantum system is distributed to spatially separated parties, it is natural to consider how the system evolves when the parties perform local quantum operations with classical communication (LOCC). However, the structure of LOCC channels is exceedingly complex, leaving many important physical problems unsolved. In this paper, we consider generalized resource theories of entanglement based on different relaxations to the class of LOCC. The behavior of various entanglement measures is studied under non-entangling channels, as well as the newly introduced classes of dually non-entangling and positive partial transpose (PPT)-preserving channels. In an effort to better understand the nature of LOCC bound entanglement, we study the problem of entanglement distillation in these generalized resource theories. We first show that unlike LOCC, general non-entangling maps can be superactivated, in the sense that two copies of the same non-entangling map can, nevertheless, be entangling. On the single-copy level, we demonstrate that every NPT entangled state can be converted into an LOCC-distillable state using channels that are both dually non-entangling and having a PPT Choi representation and that every state can be converted into an LOCC-distillable state using operations belonging to any family of polytopes that approximate LOCC. We then turn to the stochastic convertibility of multipartite pure states and show that any two states can be interconverted by any polytope approximation to the set of separable channels. Finally, as an analog to k-positive maps, we introduce and analyze the set of k-non-entangling channels.
The effect of A-site cation on ferroelectric properties in Na0.5Bi0.5TiO3-based materials: Correlation between Burns temperature and remanent polarization
Authors: Banerjee Krishnarjun , Asthana Saket
Published: April 2020

The effect of cation radius mismatch on the relaxor to paraelectric state transition temperature of the lead free ferroelectric Na0.5 − xRbxBi0.5TiO3 was examined, and the observed trend was different from manganite perovskites. The transition temperatures of these compounds were estimated from the temperature dependent dielectric curves. The nature of the dielectric curve at the transition temperature was broad unlike a normal ferroelectric. The dependency of the transition temperature on the A-site cation radius mismatch was explained through the correlation among polarizations of the polar nanoregions (PNRs). An asymmetric nature in the imaginary part of the impedance spectra was observed for the composition with higher disorder at the A-site, which is attributed to the relaxation time distribution of the PNRs. The decrement in the value of remanent polarization (Pr) with the increment in A-site substitution was also noticed. A relationship between the transition temperature from the relaxor to paraelectric state and Pr of the A-site disorder Na0.5Bi0.5TiO3-based systems was attempted to be established.
Application of recurrence quantification analysis for early detection of lean blowout in a swirl-stabilized dump combustor
Authors: De Somnath , Bhattacharya Arijit , Mondal Sirshendu , Mukhopadhyay Achintya , Sen Swarnendu
Published: April 2020

Lean blowout (LBO) is a serious issue in modern gas turbine engines that operate in a lean (premixed) mode to follow the stringent emission norms. When an engine operates with a lean fuel–air mixture, the flame becomes unstable and is at times carried out of the combustion chamber by the unburnt flow. Thus, the sudden loss of the flame, known as lean blowout, leads to fatal accidents in aircrafts and loss of production in power plants. Therefore, an in-depth analysis of lean blowout is necessary as the phenomenon involves complex interactions between flow dynamics and chemical kinetics. For understanding the complex dynamics of this phenomenon, recurrence analysis can be a very useful method. In the current study, we observe a transition to LBO as the global fuel–air ratio is reduced from stoichiometric condition and perform recurrence quantification analysis (RQA) with the CH∗ chemiluminescence data obtained experimentally. The extent of fuel–air mixing is varied with an objective of developing some robust early predictors of LBO that would work over a wide range of premixing. We find some RQA measures, such as determinism, laminarity, and trapping time, which show distinctive signature toward LBO and thereby can be used as early predictors of LBO for both premixed and partially premixed flames. Our analysis shows that the computational time for laminarity and trapping time is relatively less. However, computational time for those measures depends upon the dynamics of the combustor, size of the data taken, and choice of recurrence threshold.
Angular momentum balance and vortex production in wall-bounded flows
Authors: Paglietti A.
Published: April 2020

To produce a vortex, a torque must be applied to the fluid. In viscous fluids, the torques that produce turbulent vortices result from the loss of symmetry of the stress tensor, once the viscous friction exceeds the shear stress resistance of the fluid. In wall-bounded flows, in particular, the turbulent vortices form in a thin layer of fluid adjacent to the wall, practically coinciding with the so-called viscous sublayer, where the viscous friction reaches the largest values. This paper determines a vortex structure for this sublayer, consistent with the well-known linearity of the diagram of the mean streamwise velocity of this region. The analysis enables us to calculate the diameter, angular velocity, and interaxis of the vortices in the viscous sublayer under steady-state conditions. The lifting force that makes the vortices migrate from the wall toward the mainstream flow is determined, and the crucial role played by gyroscopic precession in the reorientation of the vortex axis is discussed.
Active learning of many-body configuration space: Application to the Cs+–water MB-nrg potential energy function as a case study
Authors: Zhai Yaoguang , Caruso Alessandro , Gao Sicun , Paesani Francesco
Published: April 2020

The efficient selection of representative configurations that are used in high-level electronic structure calculations needed for the development of many-body molecular models poses a challenge to current data-driven approaches to molecular simulations. Here, we introduce an active learning (AL) framework for generating training sets corresponding to individual many-body contributions to the energy of an N-body system, which are required for the development of MB-nrg potential energy functions (PEFs). Our AL framework is based on uncertainty and error estimation and uses Gaussian process regression to identify the most relevant configurations that are needed for an accurate representation of the energy landscape of the molecular system under examination. Taking the Cs+–water system as a case study, we demonstrate that the application of our AL framework results in significantly smaller training sets than previously used in the development of the original MB-nrg PEF, without loss of accuracy. Considering the computational cost associated with high-level electronic structure calculations, our AL framework is particularly well-suited to the development of many-body PEFs, with chemical and spectroscopic accuracy, for molecular-level computer simulations from the gas to the condensed phase.
Modulation of thermal transport in AlxGa1−xAs alloy nanowires with varying compositions
Authors: Xie Zhong-Xiang , Yu Xia , Chen Xue-Kun , Zhou Wu-Xing , Shi Yi-Min , Zhang Li-Fu
Published: April 2020

Phonon dispersion relations and thermal conductance in AlxGa1−xAs alloy nanowires with varying compositions are investigated. When x varies from 0 to 1, the lowest-energy mode remains almost unchanged, while the cutoff frequency of the high-order modes increases. The thermal conductance of AlxGa1−xAs alloy nanowires is inversely proportional to the Al content x, but proportional to the nanowire width. For a two-terminal GaAs/AlxGa1−xAs/AlAs transport system, it is found that the thermal conductance first decreases and then increases as x increases from 0 to 1. The minimum thermal conductance at the critical x = 0.66 can be observed independent of the nanowire width. A concise analysis of these results is made.
Alkyltransferase-like protein clusters scan DNA rapidly over long distances and recruit NER to alkyl-DNA lesions
Authors: Rill Natascha , Mukhortava Ann , Lorenz Sonja , Tessmer Ingrid
Published: April 2020

Alkylation of guanine bases in DNA is detrimental to cells due to its high mutagenic and cytotoxic potential and is repaired by the alkyltransferase AGT. Additionally, alkyltransferase-like proteins (ATLs), which are structurally similar to AGTs, have been identified in many organisms. While ATLs are per se catalytically inactive, strong evidence has suggested that ATLs target alkyl lesions to the nucleotide excision repair system (NER). Using a combination of single-molecule and ensemble approaches, we show here recruitment of UvrA, the initiating enzyme of prokaryotic NER, to an alkyl lesion by ATL. We further characterize lesion recognition by ATL and directly visualize DNA lesion search by highly motile ATL and ATL–UvrA complexes on DNA at the molecular level. Based on the high similarity of ATLs and the DNA-interacting domain of AGTs, our results provide important insight in the lesion search mechanism, not only by ATL but also by AGT, thus opening opportunities for controlling the action of AGT for therapeutic benefit during chemotherapy.
Media, public opinion and parliamentary agendas’ effect in political parties’ agenda-setting
Authors: Belchior Ana Maria
Published: April 2020

Why do parties pay more attention to some policy issues than to others? To what extent does policy attention
conveyed by the media, public opinion, and parliament explain party agenda-setting? And, more specifically, to what extent does
the media agenda influence other agenda effects? This paper addresses these questions in an original manner by analyzing the
influence of these three agendas – media, public opinion, and parliament – in party manifesto elaboration. The analysis relies on
an extensive database of the Portuguese Policy Agendas Project that includes media attention, voter preferences, parliamentary
questions and pledges in manifestos, between 1995 and 2015. Our findings show that the media agenda is the most influential in
party manifesto elaboration, and that the other agendas have a stronger effect when the media also give attention to the issue.
This depends, however, on the political party being in cabinet or in opposition, as well as on the economic context. These
findings have important implications for party competition literature.