bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Definition of the Landscape of Promoter DNA Hypomethylation in Liver Cancer
Authors: Stefanska Barbara , Huang Jian , Bhattacharyya Bishnu , Suderman Matthew , Hallett Michael , Han Ze-Guang , Szyf Moshe
Published: April 2023

PDF file - 3033K, Validation of MeDIP microarray results by pyrosequencing (A) and Affymetrix expression array results by QPCR (B) for selected genes in cancer and normal samples from 11 HCC patients. The demethylated genes in liver cancer were identified based on methylation microarrays. The probes that demonstrated lower methylation levels in cancer compared to adjacent normal tissue as shown in the array tracks, were chosen for validation by pyrosequencing. The position of each CpG site relative to the transcription start site is depicted in a physical map for each of the genes. All results represent mean � S.D. of two or three independent experiments; ***P < 0.001, **P <0.01, *P <0.05.
Supplementary Figure 8 from Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
Authors: Barsoum Ivraym B. , Hamilton Thomas K. , Li Xin , Cotechini Tiziana , Miles Ellen A. , Siemens D. Robert , Graham Charles H.
Published: April 2023

PDF file - 96K
Supplementary Figure 4 from Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
Authors: Barsoum Ivraym B. , Hamilton Thomas K. , Li Xin , Cotechini Tiziana , Miles Ellen A. , Siemens D. Robert , Graham Charles H.
Published: April 2023

PDF file - 126K
Supplementary Figure Legends 1-3 from Combination Therapy with HSP90 Inhibitor 17-DMAG Reconditions the Tumor Microenvironment to Improve Recruitment of Therapeutic T cells
Authors: Rao Aparna , Taylor Jennifer L. , Chi-Sabins Nina , Kawabe Mayumi , Gooding William E. , Storkus Walter J.
Published: April 2023

PDF file - 318K
Supplementary References from MicroRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2
Authors: Ma Stephanie , Chan Yuen Piu , Kwan Pak Shing , Lee Terence K. , Yan Mingxia , Tang Kwan Ho , Ling Ming Tat , Vielkind Juergen R. , Guan Xin-Yuan , Chan Kwok Wah
Published: April 2023

Supplementary References from MicroRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2
Supplementary Table 1 from RNA Helicase DDX5 Is a p53-Independent Target of ARF That Participates in Ribosome Biogenesis
Authors: Saporita Anthony J. , Chang Hsiang-Chun , Winkeler Crystal L. , Apicelli Anthony J. , Kladney Raleigh D. , Wang Jianbo , Townsend R. Reid , Michel Loren S. , Weber Jason D.
Published: April 2023

PDF file - 46K
Supplementary Figure 3 from RNA Helicase DDX5 Is a p53-Independent Target of ARF That Participates in Ribosome Biogenesis
Authors: Saporita Anthony J. , Chang Hsiang-Chun , Winkeler Crystal L. , Apicelli Anthony J. , Kladney Raleigh D. , Wang Jianbo , Townsend R. Reid , Michel Loren S. , Weber Jason D.
Published: April 2023

PDF file - 2.8MB
Supplementary Figure 1 from SMAC Mimetic (JP1201) Sensitizes Non–Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α–Independent Manner
Authors: Greer Rachel M. , Peyton Michael , Larsen Jill E. , Girard Luc , Xie Yang , Gazdar Adi F. , Harran Patrick , Wang Lai , Brekken Rolf A. , Wang Xiaodong , Minna John D.
Published: April 2023

PDF file - 1MB, A, H2087 B, H157 and C, H460 were treated with cisplatin (black circles) or cisplatin in combination with 10 mM JP1201 (open circles). D, H2887 E, H358 and F, H157 were treated with doxorubicin (black circles) or doxorubicin in combination with 10 mM JP1201 (open circles). G, H1395 H, H441 and I, H460 were treated with gemcitabine (black circles) or gemcitabine in combination with 10 mM JP1201 (open circles). J, H1819 K, H2882 and L, H460 were treated with paclitaxel (black circles) or paclitaxel in combination with 10 mM JP1201 (open circles). M, H2073 N, A549 and O, H2087 were treated with vinorelbine (black circles) or vinorelbine in combination with 10 mM JP1201 (open circles). P, H157 Q, A549 and R, H2073 (bottom) were treated with erlotinib (black circles) or erlotinib in combination with 10 mM JP1201 (open circles).
Supplementary Figure 2 from The RASSF3 Candidate Tumor Suppressor Induces Apoptosis and G1–S Cell-Cycle Arrest via p53
Authors: Kudo Takumi , Ikeda Mitsunobu , Nishikawa Misa , Yang Zeyu , Ohno Kikuo , Nakagawa Kentaro , Hata Yutaka
Published: April 2023

PDF file - 102K, This figure demonstrates the validities of knockdowns of RASSF3 (in HeLa, U2OS, and MCF-7 cells), p53 (in HeLa and U2OS cells), and MDM2 (in HeLa and U2OS cells)
Supplementary Tables 1-2 from INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells
Authors: Morris Christelle , Tomimatsu Nozomi , Richard Derek J. , Cluet David , Burma Sandeep , Khanna Kum Kum , Jalinot Pierre
Published: April 2023

PDF file - 28K
Supplementary Figures 1-7 from INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells
Authors: Morris Christelle , Tomimatsu Nozomi , Richard Derek J. , Cluet David , Burma Sandeep , Khanna Kum Kum , Jalinot Pierre
Published: April 2023

PDF file - 91.1MB
Supplementary Figure 6 from The Unfolded Protein Response Induces the Angiogenic Switch in Human Tumor Cells through the PERK/ATF4 Pathway
Authors: Wang Yugang , Alam Goleeta N. , Ning Yu , Visioli Fernanda , Dong Zhihong , Nör Jacques E. , Polverini Peter J.
Published: April 2023

PDF file - 92K, IL8 responds in a distinct manner to UPR activation compared to other proangioenic factors
Supplementary Table 2 from TRPM7 Is Required for Breast Tumor Cell Metastasis
Authors: Middelbeek Jeroen , Kuipers Arthur J. , Henneman Linda , Visser Daan , Eidhof Ilse , van Horssen Remco , Wieringa Bé , Canisius Sander V. , Zwart Wilbert , Wessels Lodewyk F. , Sweep Fred C.G.J. , Bult Peter , Span Paul N. , van Leeuwen Frank N. , Jalink Kees
Published: April 2023

PDF file - 96K, TRPM7 expression levels and clinical parameters
Supplementary Figure 5 from The Unfolded Protein Response Induces the Angiogenic Switch in Human Tumor Cells through the PERK/ATF4 Pathway
Authors: Wang Yugang , Alam Goleeta N. , Ning Yu , Visioli Fernanda , Dong Zhihong , Nör Jacques E. , Polverini Peter J.
Published: April 2023

PDF file - 124K, UPR regulates blood vessel formation and tumor proliferation
Supplementary Figure 5 from TRPM7 Is Required for Breast Tumor Cell Metastasis
Authors: Middelbeek Jeroen , Kuipers Arthur J. , Henneman Linda , Visser Daan , Eidhof Ilse , van Horssen Remco , Wieringa Bé , Canisius Sander V. , Zwart Wilbert , Wessels Lodewyk F. , Sweep Fred C.G.J. , Bult Peter , Span Paul N. , van Leeuwen Frank N. , Jalink Kees
Published: April 2023

PDF file - 114K, Uncropped immunoblots and autoradiograms
Supplementary Table 2 from Integrin α5β1 Plays a Critical Role in Resistance to Temozolomide by Interfering with the p53 Pathway in High-Grade Glioma
Authors: Janouskova Hana , Maglott Anne , Leger David Y. , Bossert Catherine , Noulet Fanny , Guerin Eric , Guenot Dominique , Pinel Sophie , Chastagner Pascal , Plenat François , Entz-Werle Natacha , Lehmann-Che Jacqueline , Godet Julien , Martin Sophie , Teisinger Jan , Dontenwill Monique
Published: April 2023

PDF file - 23K, Proportion of grade III and grade IV glioma in the subgroups of patients with high and low Alpha5 integrin mRNA expression in the 3 cohorts of patients included in this study
Supplementary Legends for Figures 1-14, and Tables 1-6 from Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and Oncogenesis
Authors: Dulak Austin M. , Schumacher Steven E. , van Lieshout Jasper , Imamura Yu , Fox Cameron , Shim Byoungyong , Ramos Alex H. , Saksena Gordon , Baca Sylvan C. , Baselga Jose , Tabernero Josep , Barretina Jordi , Enzinger Peter C. , Corso Giovanni , Roviello Franco , Lin Lin , Bandla Santhoshi , Luketich James D. , Pennathur Arjun , Meyerson Matthew , Ogino Shuji , Shivdasani Ramesh A. , Beer David G. , Godfrey Tony E. , Beroukhim Rameen , Bass Adam J.
Published: April 2023

PDF file - 103K
Supplementary Figure 1 from Effective Combination Therapy for Malignant Glioma with TRAIL-Secreting Mesenchymal Stem Cells and Lipoxygenase Inhibitor MK886
Authors: Kim Seong Muk , Woo Ji Sun , Jeong Chang Hyun , Ryu Chung Heon , Lim Jung Yeon , Jeun Sin-Soo
Published: April 2023

PDF file - 2.1MB, Cytotoxic effect of the treatment with AA861 on glioma cell death
Supplementary Figure 5 from Cyclin D1 Activity Regulates Autophagy and Senescence in the Mammary Epithelium
Authors: Brown Nelson E. , Jeselsohn Rinath , Bihani Teeru , Hu Miaofen G. , Foltopoulou Parthena , Kuperwasser Charlotte , Hinds Philip W.
Published: April 2023

PDF file - 93K, Characterization of autopahgy in immortalized MECs
Supplementary Figure 5 from Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
Authors: Ying Songmin , Hamdy Freddie C. , Helleday Thomas
Published: April 2023

PDF file - 79K, Stalled replication forks are protected from degradation in PARP inhibitor-resistant cells
Supplementary Figure 5 from Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow–Derived Monocytes
Authors: Iyer Vandana , Klebba Ina , McCready Jessica , Arendt Lisa M. , Betancur-Boissel Monica , Wu Meng-Fen , Zhang Xiaomei , Lewis Michael T. , Kuperwasser Charlotte
Published: April 2023

PDF file - 134K, ER expression levels in primary macrophages and RAW264.7 macrophages
Supplementary Figure 1 from Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
Authors: Ying Songmin , Hamdy Freddie C. , Helleday Thomas
Published: April 2023

PDF file - 52K, Mre11 foci formation in BRCA2 deficient cells is independent of PARP activity
Supplementary Figure 3 from Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
Authors: Wojtkowiak Jonathan W. , Rothberg Jennifer M. , Kumar Virendra , Schramm Karla J. , Haller Edward , Proemsey Joshua B. , Lloyd Mark C. , Sloane Bonnie F. , Gillies Robert J.
Published: April 2023

PDF file - 431K, Histological analysis of in-vivo LC3 expression in HS766T subcutaneous tumors buffered with sodium bicarbonate. (A) Whole cell lysates from HS766T cells cultured at neutral pH 7.4 or pH 6.7 for 48 hours were analyzed for LC3-II expression. (B) Positive pixel analysis was completed for LC3 staining on whole tissue cross sections from HS766T tumors treated with tap or NaHCO3. An overall significant decrease in total positive and strong positive LC3 pixels was observed in NaHCO3 treated samples. The data are plotted as the mean � standard deviation of three whole tumor cross sections from each treatment group. (C) A 5x magnification of representative tissue regions from HS766T tumors stained for LC3
Supplementary Tables 1-6 from ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion
Authors: Vendrell Julie A. , Thollet Aurélie , Nguyen Nhan T. , Ghayad Sandra E. , Vinot Stéphanie , Bièche Ivan , Grisard Evelyne , Josserand Véronique , Coll Jean-Luc , Roux Pierre , Corbo Laura , Treilleux Isabelle , Rimokh Ruth , Cohen Pascale A.
Published: April 2023

PDF file - 104K, complementary tables on breast tumor clinical information, primers used for ChIP experiments and ZNF217-associated gene-expression deregulations
Supplementary Table 2 from Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling
Authors: Gasperini Paola , Espigol-Frigole Georgina , McCormick Peter J. , Salvucci Ombretta , Maric Dragan , Uldrick Thomas S. , Polizzotto Mark N. , Yarchoan Robert , Tosato Giovanna
Published: April 2023

PDF file - 119K
Supplementary Figure 4 from CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis
Authors: Thomas Shibu , Harding Michael A. , Smith Steven C. , Overdevest Jonathan B. , Nitz Matthew D. , Frierson Henry F. , Tomlins Scott A. , Kristiansen Glen , Theodorescu Dan
Published: April 2023

PDF file - 88K, Western blot and ChIP for HIF-1beta in human bladder cancer cells
Supplementary Figures 1-5, Tables 1-2 from Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells
Authors: Zhou Yunfei , Tozzi Federico , Chen Jinyu , Fan Fan , Xia Ling , Wang Jinrong , Gao Guang , Zhang Aijun , Xia Xuefeng , Brasher Heather , Widger William , Ellis Lee M. , Weihua Zhang
Published: April 2023

PDF file - 113K
Supplementary Figure 2 from In Vivo Imaging of Drug-Induced Mitochondrial Outer Membrane Permeabilization at Single-Cell Resolution
Authors: Earley Sarah , Vinegoni Claudio , Dunham Joshua , Gorbatov Rostic , Feruglio Paolo Fumene , Weissleder Ralph
Published: April 2023

PDF file, 289KB, Fig. S2: Histological analysis of HT1080 H2B-mCherry tumors stained with Annexin V.
Supplementary Figure 4 from Opposing Effects of Pigment Epithelium–Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage
Authors: Fitzgerald Daniel P. , Subramanian Preeti , Deshpande Monika , Graves Christian , Gordon Ira , Qian Yongzhen , Snitkovsky Yeva , Liewehr David J. , Steinberg Seth M. , Paltán-Ortiz José D. , Herman Mary M. , Camphausen Kevin , Palmieri Diane , Becerra S. Patricia , Steeg Patricia S.
Published: April 2023

PDF file - 4.9MB
Supplementary Table 1 from Global Quantitative Phosphoproteome Analysis of Human Tumor Xenografts Treated with a CD44 Antagonist
Authors: Weigand Stefan , Herting Frank , Maisel Daniela , Nopora Adam , Voss Edgar , Schaab Christoph , Klammer Martin , Tebbe Andreas
Published: April 2023

XLS file - 3.5M, Phosphoproteomics Raw Data
Supplementary Materials and Methods from An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
Authors: Huang Xiumei , Dong Ying , Bey Erik A. , Kilgore Jessica A. , Bair Joseph S. , Li Long-Shan , Patel Malina , Parkinson Elizabeth I. , Wang Yiguang , Williams Noelle S. , Gao Jinming , Hergenrother Paul J. , Boothman David A.
Published: April 2023

PDF file - 133K, A detailed description of all Materials and Methods used in the Supplemental Figures and Tables.
Supplementary Figure 1 from Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer
Authors: Lenos Kristiaan , Grawenda Anna M. , Lodder Kirsten , Kuijjer Marieke L. , Teunisse Amina F.A.S. , Repapi Emmanouela , Grochola Lukasz F. , Bartel Frank , Hogendoorn Pancras C.W. , Wuerl Peter , Taubert Helge , Cleton-Jansen Anne-Marie , Bond Gareth L. , Jochemsen Aart G.
Published: April 2023

PDF file - 565K, Nutlin-3 response in osteosarcoma cell lines. Treated osteosarcoma cells were analyzed by Western blotting and FACS analysis
Supplementary Figures 4-5 from An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
Authors: Huang Xiumei , Dong Ying , Bey Erik A. , Kilgore Jessica A. , Bair Joseph S. , Li Long-Shan , Patel Malina , Parkinson Elizabeth I. , Wang Yiguang , Williams Noelle S. , Gao Jinming , Hergenrother Paul J. , Boothman David A.
Published: April 2023

PDF file - 514K, NQO1-dependent nucleotide depletion in response to DNQ. Supplemental Figure 5. PARP1 hyperactivation is essential for NQO1-dependent ATP loss.
Supplementary Figures 1-2 from An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis
Authors: Huang Xiumei , Dong Ying , Bey Erik A. , Kilgore Jessica A. , Bair Joseph S. , Li Long-Shan , Patel Malina , Parkinson Elizabeth I. , Wang Yiguang , Williams Noelle S. , Gao Jinming , Hergenrother Paul J. , Boothman David A.
Published: April 2023

PDF file - 990K, Structures of quinones used in the study, including DNQ and �-lap. Supplemental Figure 2. Minimum time determination for DNQ lethality and demonstration of NQO1-mediated DNA lesion formation by alkaline comet assays.
Supplementary Figure 3 from Modulation of Glucose Metabolism by CD44 Contributes to Antioxidant Status and Drug Resistance in Cancer Cells
Authors: Tamada Mayumi , Nagano Osamu , Tateyama Seiji , Ohmura Mitsuyo , Yae Toshifumi , Ishimoto Takatsugu , Sugihara Eiji , Onishi Nobuyuki , Yamamoto Takehiro , Yanagawa Hiroshi , Suematsu Makoto , Saya Hideyuki
Published: April 2023

PDF file - 324K
Supplementary Figure 2 from Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity
Authors: Cheng Fengdong , Wang Hongwei , Horna Pedro , Wang Zi , Shah Bijal , Sahakian Eva , Woan Karrune V. , Villagra Alejandro , Pinilla-Ibarz Javier , Sebti Said , Smith Mitchell , Tao Jianguo , Sotomayor Eduardo M.
Published: April 2023

PDF file - 426K, Percent of T-cells
Supplementary Figure Legends 1-3 from Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice
Authors: Tsoli Maria , Moore Melissa , Burg Dominic , Painter Arran , Taylor Ryland , Lockie Sarah H. , Turner Nigel , Warren Alessandra , Cooney Greg , Oldfield Brian , Clarke Stephen , Robertson Graham
Published: April 2023

PDF file - 72K
Supplementary Figure 1 from Activation of Thermogenesis in Brown Adipose Tissue and Dysregulated Lipid Metabolism Associated with Cancer Cachexia in Mice
Authors: Tsoli Maria , Moore Melissa , Burg Dominic , Painter Arran , Taylor Ryland , Lockie Sarah H. , Turner Nigel , Warren Alessandra , Cooney Greg , Oldfield Brian , Clarke Stephen , Robertson Graham
Published: April 2023

PDF file - 175K, Effects of tumor C26 inoculation and food restriction on energy expenditure of mice
Supplementary Appendix from Circulating Insulin-Like Growth Factors and IGF-Binding Proteins in PSA-Detected Prostate Cancer: The Large Case–Control Study ProtecT
Authors: Rowlands Mari-Anne , Holly Jeff M.P. , Gunnell David , Donovan Jenny , Lane J. Athene , Hamdy Freddie , Neal David E. , Oliver Steven , Smith George Davey , Martin Richard M.
Published: April 2023

PDF file - 83K
Supplementary Table 1 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Authors: Waaler Jo , Machon Ondrej , Tumova Lucie , Dinh Huyen , Korinek Vladimir , Wilson Steven Ray , Paulsen Jan Erik , Pedersen Nina Marie , Eide Tor J. , Machonova Olga , Gradl Dietmar , Voronkov Andrey , von Kries Jens Peter , Krauss Stefan
Published: April 2023

XLS file - 574K, The table shows the results from an Illumina expression analysis that examined mRNA from SW480 CRC cells exposed to JW55 for 72 hours.
Supplementary Figure 2 from Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells
Authors: Goldstein Matthew J. , Kohrt Holbrook E. , Houot Roch , Varghese Bindu , Lin Jack T. , Swanson Erica , Levy Ronald
Published: April 2023

PDF file - 308K, Phenotypic fidelity of transferred T cell subsets.
Supplementary Figure 2 from Frequent PVT1 Rearrangement and Novel Chimeric Genes PVT1-NBEA and PVT1-WWOX Occur in Multiple Myeloma with 8q24 Abnormality
Authors: Nagoshi Hisao , Taki Tomohiko , Hanamura Ichiro , Nitta Masakazu , Otsuki Takemi , Nishida Kazuhiro , Okuda Keiko , Sakamoto Natsumi , Kobayashi Satoru , Yamamoto-Sugitani Mio , Tsutsumi Yasuhiko , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Kuroda Junya , Taniwaki Masafumi
Published: April 2023

PDF file - 243K, Genome copy number changes at 8q24 detected by SNP array analysis
Supplementary Table 2 from Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell Senescence Factors
Authors: Horiguchi Michiko , Koyanagi Satoru , Okamoto Akinori , Suzuki Satoshi O. , Matsunaga Naoya , Ohdo Shigehiro
Published: April 2023

PDF file - 163K
Supplementary Table 2 from Novel Transcriptional Targets of the SRY-HMG Box Transcription Factor SOX4 Link Its Expression to the Development of Small Cell Lung Cancer
Authors: Castillo Sandra D. , Matheu Ander , Mariani Niccolo , Carretero Julian , Lopez-Rios Fernando , Lovell-Badge Robin , Sanchez-Cespedes Montse
Published: April 2023

PDF file - 38K
Supplementary Table 1 from Novel Transcriptional Targets of the SRY-HMG Box Transcription Factor SOX4 Link Its Expression to the Development of Small Cell Lung Cancer
Authors: Castillo Sandra D. , Matheu Ander , Mariani Niccolo , Carretero Julian , Lopez-Rios Fernando , Lovell-Badge Robin , Sanchez-Cespedes Montse
Published: April 2023

PDF file - 59K, Transcripts that were down-regulated and up-regulated upon SOX4 depletion
Supplementary Figure 4 from Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells
Authors: Ohata Hirokazu , Ishiguro Tatsuya , Aihara Yuki , Sato Ai , Sakai Hiroaki , Sekine Shigeki , Taniguchi Hirokazu , Akasu Takayuki , Fujita Shin , Nakagama Hitoshi , Okamoto Koji
Published: April 2023

PDF file - 85K, Inhibition of CD44 suppresses spheroid formation
Supplementary Figure 3 from Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells
Authors: Ohata Hirokazu , Ishiguro Tatsuya , Aihara Yuki , Sato Ai , Sakai Hiroaki , Sekine Shigeki , Taniguchi Hirokazu , Akasu Takayuki , Fujita Shin , Nakagama Hitoshi , Okamoto Koji
Published: April 2023

PDF file - 114K, CD44high cells in the spheroids show characteristics of cancer stem cells
Supplementary Figure 2 from Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer–Initiating Cells
Authors: Ohata Hirokazu , Ishiguro Tatsuya , Aihara Yuki , Sato Ai , Sakai Hiroaki , Sekine Shigeki , Taniguchi Hirokazu , Akasu Takayuki , Fujita Shin , Nakagama Hitoshi , Okamoto Koji
Published: April 2023

PDF file - 311K, The spheroids formed in the presence of ROCK inhibitor express colon cancer stem cell markers, differentiate into epithelial-like cells, and are capable of forming tumors in mice
Supplementary Figure 2 from CD44s Regulates the TGF-β–Mediated Mesenchymal Phenotype and Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
Authors: Mima Kosuke , Okabe Hirohisa , Ishimoto Takatsugu , Hayashi Hiromitsu , Nakagawa Shigeki , Kuroki Hideyuki , Watanabe Masayuki , Beppu Toru , Tamada Mayumi , Nagano Osamu , Saya Hideyuki , Baba Hideo
Published: April 2023

PDF file - 5.1MB, Downregulation of CD44 attenuates the mesenchymal phenotype in three HCC cell lines that express high levels of CD44s
Supplementary Figure 4 from Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Authors: Adinolfi Elena , Raffaghello Lizzia , Giuliani Anna Lisa , Cavazzini Luigi , Capece Marina , Chiozzi Paola , Bianchi Giovanna , Kroemer Guido , Pistoia Vito , Di Virgilio Francesco
Published: April 2023

PDF file, 72KB, Fig. S4. Effect of P2X7 silencing on ACN neuroblastoma growth. Panel A, P2X7 expression in ACN neuroblastoma cells transfected with P2X7-specific or scrambled shRNA. Cell protein was extracted, run on SDS PAGE, blotted and stained with an anti-P2X7-selective polyclonal Ab. Panel B, densitometric analysis of P2X7 bands. Panel C, volumes of tumors excised at d 18 post-inoculum.
Supplementary Figure 2 from Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter
Authors: Basseville Agnes , Tamaki Akina , Ierano Caterina , Trostel Shana , Ward Yvona , Robey Robert W. , Hegde Ramanujan S. , Bates Susan E.
Published: April 2023

PDF file - 52K, Ubiquitination state of ABCG2
Supplementary Table 1 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

XLS file - 102K, TCGA data for TP53BP1 in the GBM dataset
Supplementary Figures 1-8 from MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors
Authors: Turke Alexa B. , Song Youngchul , Costa Carlotta , Cook Rebecca , Arteaga Carlos L. , Asara John M. , Engelman Jeffrey A.
Published: April 2023

PDF file - 515K, Supplemenal figures 1-8 support the main figures in the manuscript, and include characterization of compounds and target inhibition, quantification of ERBB3 mRNA and HRG ligand, cell line characterization, and data supporting mass spectrometry experiments.
Supplementary Figure 2 from 53BP1 Is a Haploinsufficient Tumor Suppressor and Protects Cells from Radiation Response in Glioma
Authors: Squatrito Massimo , Vanoli Fabio , Schultz Nikolaus , Jasin Maria , Holland Eric C.
Published: April 2023

PDF file - 310K, 53BP1 null mouse cells, but not heterozygous, and robust silencing in GBM cells lead to high sensitivity to IR
Supplementary Table 6 from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Authors: Girgis Andrew H. , Iakovlev Vladimir V. , Beheshti Ben , Bayani Jane , Squire Jeremy A. , Bui Anna , Mankaruos Marina , Youssef Youssef , Khalil Bishoy , Khella Heba , Pasic Maria , Yousef George M.
Published: April 2023

PDF file - 30K, Select genes significantly methylated in tumor versus normal kidney in regions associated with copy-number aberrations
Supplementary Table 3 from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Authors: Girgis Andrew H. , Iakovlev Vladimir V. , Beheshti Ben , Bayani Jane , Squire Jeremy A. , Bui Anna , Mankaruos Marina , Youssef Youssef , Khalil Bishoy , Khella Heba , Pasic Maria , Yousef George M.
Published: April 2023

PDF file - 50K, Significantly expressed genes located on the 3p and 5q chromosomal arms among aberrant versus normal kidney and integration of protein and miRNA data in ccRCC
Supplementary Figure 4 from Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
Authors: Zaytseva Yekaterina Y. , Rychahou Piotr G. , Gulhati Pat , Elliott Victoria A. , Mustain William C. , O'Connor Kathleen , Morris Andrew J. , Sunkara Manjula , Weiss Heidi L. , Lee Eun Y. , Evers B. Mark
Published: April 2023

PDF file - 136K, Images of GFP-positive cells in whole lungs from mice injected with KM20-NTC-Luc/GFP and KM20-FASNshRNA-Luc/GFP cells.
Supplementary Figure 3 from Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
Authors: Zaytseva Yekaterina Y. , Rychahou Piotr G. , Gulhati Pat , Elliott Victoria A. , Mustain William C. , O'Connor Kathleen , Morris Andrew J. , Sunkara Manjula , Weiss Heidi L. , Lee Eun Y. , Evers B. Mark
Published: April 2023

PDF file - 129K, A, expression of CD44 on the cell surface of HT29 NTC cells treated with either DMSO or 200 �M of 2-BP for 3 h, and HT29 FASN shRNA cells assessed by direct staining with CD44-FITC antibody and flow cytometry analysis. B, immunoblot analysis for FASN and CD44 in the cytoplasmic and membrane fractions of HT29 NTC cells treated with either DMSO or 200 �M of 2-BP for 3 h, and in the cytoplasmic and membrane fractions of HT29 FASN shRNA cells.
Supplementary Figure 2 from Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
Authors: Zaytseva Yekaterina Y. , Rychahou Piotr G. , Gulhati Pat , Elliott Victoria A. , Mustain William C. , O'Connor Kathleen , Morris Andrew J. , Sunkara Manjula , Weiss Heidi L. , Lee Eun Y. , Evers B. Mark
Published: April 2023

PDF file - 81K, Morphological changes in CRC cell lines with targeted inhibition of ACLY and FASN.
Supplementary Figure 1 from Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer
Authors: Zaytseva Yekaterina Y. , Rychahou Piotr G. , Gulhati Pat , Elliott Victoria A. , Mustain William C. , O'Connor Kathleen , Morris Andrew J. , Sunkara Manjula , Weiss Heidi L. , Lee Eun Y. , Evers B. Mark
Published: April 2023

PDF file - 431K, Expression of FASN in normal colon mucosa, primary tumors and matched metastatic liver tumors from stage IV CRC patients. Accumax Tissue Array A203 (IV). n=14 cases. Four spots for each cancer case (56 spots) and 14 non-neoplastic spots were analyzed. x200 and x400 magnifications were used. Immunoreactivity score was determined according to a semiquantitive method as described in Materials and Methods.
Supplementary Figure 2 from Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing
Authors: Narayan Azeet , Carriero Nicholas J. , Gettinger Scott N. , Kluytenaar Jeannie , Kozak Kevin R. , Yock Torunn I. , Muscato Nicole E. , Ugarelli Pedro , Decker Roy H. , Patel Abhijit A.
Published: April 2023

PDF file - 63K, ctDNA levels in patients with fewer than 3 time-points
Supplementary Video 6 from Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer
Authors: Withana Nimali P. , Blum Galia , Sameni Mansoureh , Slaney Clare , Anbalagan Arulselvi , Olive Mary B. , Bidwell Bradley N. , Edgington Laura , Wang Ling , Moin Kamiar , Sloane Bonnie F. , Anderson Robin L. , Bogyo Matthew S. , Parker Belinda S.
Published: April 2023

AVI file - 4.7MB, Degradation of collagen I by 4T1.2 cells + CA-074 inhibitor
Supplementary Figure 1 from Critical Function for Nuclear Envelope Protein TMEM209 in Human Pulmonary Carcinogenesis
Authors: Fujitomo Takashi , Daigo Yataro , Matsuda Koichi , Ueda Koji , Nakamura Yusuke
Published: April 2023

PDF file - 205K, Interaction between NUP205 and TMEM209/c-Myc
Supplementary Figure 7 from Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis
Authors: Zhang Yi , Cheng Yan , Ren Xingcong , Hori Tsukasa , Huber-Keener Kathryn J. , Zhang Li , Yap Kai Lee , Liu David , Shantz Lisa , Qin Zheng-Hong , Zhang Suping , Wang Jianrong , Wang Hong-Gang , Shih Ie-Ming , Yang Jin-Ming
Published: April 2023

PDF file - 76K, Effect of NAC1 status on proliferation of immortalized MEFs transduced with Ras
Supplementary Figure 4 from Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis
Authors: Zhang Yi , Cheng Yan , Ren Xingcong , Hori Tsukasa , Huber-Keener Kathryn J. , Zhang Li , Yap Kai Lee , Liu David , Shantz Lisa , Qin Zheng-Hong , Zhang Suping , Wang Jianrong , Wang Hong-Gang , Shih Ie-Ming , Yang Jin-Ming
Published: April 2023

PDF file - 83K, Expression of p15, p16 and p18 in NAC1-activated or -inactivated tumor cells with or without irradiation treatment
Supplementary Table 1 from Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models
Authors: Zhang Qiuyang , Liu Sen , Ge Dongxia , Zhang Qingsong , Xue Yun , Xiong Zhenggang , Abdel-Mageed Asim B. , Myers Leann , Hill Steven M. , Rowan Brian G. , Sartor Oliver , Melamed Jonathan , Chen Zhenbang , You Zongbing
Published: April 2023

PDF file - 63K, PCR Primer Sequences
Supplementary Figure 5 from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: April 2023

PDF file - 78K, CD44-ICD expression in human thyroid cancer cell lines
Supplementary Figure 2 from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: April 2023

PDF file - 175K, CD44-ICD-CREB complex in human PTC cell lines
Supplementary Figure 3 from Chromogranin A Regulates Tumor Self-Seeding and Dissemination
Authors: Dondossola Eleonora , Crippa Luca , Colombo Barbara , Ferrero Elisabetta , Corti Angelo
Published: April 2023

PDF file - 101K
Supplementary Figure 1 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: April 2023

PDF file - 517K
Supplementary Figure 1 from Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
Authors: Cubillos-Ruiz Juan R. , Baird Jason R. , Tesone Amelia J. , Rutkowski Melanie R. , Scarlett Uciane K. , Camposeco-Jacobs Ana L. , Anadon-Arnillas Jorge , Harwood Noah M. , Korc Murray , Fiering Steven N. , Sempere Lorenzo F. , Conejo-Garcia Jose R.
Published: April 2023

PDF file - 178K, Enhanced local and splenic anti-tumor responses in mice treated with anti-CD40 and Dmi155-PEI.
Supplementary Figures 1-4 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: April 2023

PDf file - 518K
Supplementary Table 1 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: April 2023

PDF file - 66K, P53 and 14q32/22q11 characteristics of HMCLs
Supplementary Figure 4 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: April 2023

PDF file - 137K, Nutlin3a increased DR5 expression via p53
Supplementary Figure 3 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: April 2023

PDF file - 49K, Nutlin-3a did not increase activation or recruitment of caspase 8 within DR4 DISC
Supplementary Figure 2 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: April 2023

PDF file - 74K, Nutlin-3a and melphalan induced p53 expression and caspase 3 cleavage
Supplementary Methods and Materials from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: April 2023

PDF file - 192K
Supplementary Figure Legend from CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer
Authors: Pal Anupama , Huang Wei , Li Xin , Toy Kathy A. , Nikolovska-Coleska Zaneta , Kleer Celina G.
Published: April 2023

PDF file, 91K.
Supplementary Figure 5 from Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF-α–Independent Apoptosis
Authors: Eschenburg Georg , Eggert Angelika , Schramm Alexander , Lode Holger N. , Hundsdoerfer Patrick
Published: April 2023

PDF file - 298K, Effect of LBW242 and etoposide treatment on TNF-� expression.
Supplementary Tables 2-8 from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: April 2023

PDF file - 41K, Table S2: EGFR gene copy number in neurospheres and the corresponding original glioblastomas. Table S3: Immunophenotype of neurospheres. Table S4: EGFR gene amplification, Met expression, and MET gene alterations in glioblastomas and corresponding neurospheres. Table S5: Multiple transcriptional signatures in Met-neg and Met-pos neurospheres. Table S6: Immunohistochemistry on tumors derived from neurospheres. Table S8: Antibodies used in flow-cytometric analysis
Supplementary Table 1 from Leptin and Soluble Leptin Receptor in Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition Cohort
Authors: Aleksandrova Krasimira , Boeing Heiner , Jenab Mazda , Bueno-de-Mesquita H. Bas , Jansen Eugene , van Duijnhoven Fränzel J. B. , Rinaldi Sabina , Fedirko Veronika , Romieu Isabelle , Riboli Elio , Gunter Marc J. , Westphal Sabine , Overvad Kim , Tjønneland Anne , Halkjær Jytte , Racine Antoine , Boutron-Ruault Marie-Christine , Clavel-Chapelon Françoise , Kaaks Rudolf , Lukanova Annekatrin , Trichopoulou Antonia , Lagiou Pagona , Trichopoulos Dimitrios , Mattiello Amalia , Pala Valeria , Palli Domenico , Tumino Rosario , Vineis Paolo , Buckland Genevieve , Sánchez María-José , Amiano Pilar , Huerta José María , Barricarte Aurelio , Menéndez Virginia , Peeters Petra H. , Söderberg Stefan , Palmqvist Richard , Allen Naomi E. , Crowe Francesca L. , Khaw Kay-Tee , Wareham Nickolas , Pischon Tobias
Published: April 2023

PDF file - 58K, Median concentrations of leptin and sOB-R by tumor stage and cancer location, the European Prospective Investigation into Cancer and Nutrition (EPIC), 1992-2003
Supplementary Table 1 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: April 2023

Supplementary Table 1 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Figure 4 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
Authors: Luo Zhongguang , Yu Guangyang , Lee Hyuk Woo , Li Lihui , Wang Lingyan , Yang Dongqin , Pan Yongfu , Ding Chan , Qian Jing , Wu Lijun , Chu Yiwei , Yi Jing , Wang Xiangdong , Sun Yi , Jeong Lak Shin , Liu Jie , Jia Lijun
Published: April 2023

PDF file - 924K, No obvious dysfunction of liver, kidney or muscle of animals was observed post MLN4924 treatment
Supplementary Figure 3 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
Authors: Luo Zhongguang , Yu Guangyang , Lee Hyuk Woo , Li Lihui , Wang Lingyan , Yang Dongqin , Pan Yongfu , Ding Chan , Qian Jing , Wu Lijun , Chu Yiwei , Yi Jing , Wang Xiangdong , Sun Yi , Jeong Lak Shin , Liu Jie , Jia Lijun
Published: April 2023

PDF file - 1MB, MLN4924 induced more apoptosis in MEF-Atg7-KO compared to MEF-Atg7-WT
Supplementary Figures 1-6 from Transcriptional Signatures of Ral GTPase Are Associated with Aggressive Clinicopathologic Characteristics in Human Cancer
Authors: Smith Steven C. , Baras Alexander S. , Owens Charles R. , Dancik Garrett , Theodorescu Dan
Published: April 2023

PDF file - 860K, Comparison of immunohistochemical evaluation of Ral paralog expression and mRNA Ral expression signature in human tumors as a function of patient outcome
Supplementary Video 2a from Unexpected Dissemination Patterns in Lymphoma Progression Revealed by Serial Imaging within a Murine Lymph Node
Authors: Ito Ken , Smith Bryan Ronain , Parashurama Natesh , Yoon Joon-Kee , Song Si Yeol , Miething Cornelius , Mallick Parag , Lowe Scott , Gambhir Sanjiv Sam
Published: April 2023

MOV file - 6.2MB, Observation of behavior between control mouse and LNIWC implanted mouse (LNIWC mouse):Mouse videos were acquired on day 12 after implantation of either LNIWC or control mouse. No difference in behavior was observed between LNIWC-implanted mice and control mice without the LNIWC.
Supplementary Figure 1 from Increased CD8+ T-cell Function following Castration and Immunization Is Countered by Parallel Expansion of Regulatory T Cells
Authors: Tang Shuai , Moore Miranda L. , Grayson Jason M. , Dubey Purnima
Published: April 2023

PDF file - 1.3MB
Supplementary Methods and Figures from Cooperation and Antagonism among Cancer Genes: The Renal Cancer Paradigm
Authors: Peña-Llopis Samuel , Christie Alana , Xie Xian-Jin , Brugarolas James
Published: April 2023

PDF file, 87K, Cooperation and antagonism among cancer genes: the renal cancer paradigm. Supplementary Figure 1. Kaplan-Meier curves of overall survival for tumors with mutations in PBRM1 and SETD2.
Supplementary Figure 4 from Transcription Factor YY1 Contributes to Tumor Growth by Stabilizing Hypoxia Factor HIF-1α in a p53-Independent Manner
Authors: Wu Shourong , Kasim Vivi , Kano Mitsunobu R. , Tanaka Sayaka , Ohba Shinsuke , Miura Yutaka , Miyata Kanjiro , Liu Xueying , Matsuhashi Ako , Chung Ung-il , Yang Li , Kataoka Kazunori , Nishiyama Nobuhiro , Miyagishi Makoto
Published: April 2023

PDF file - 101K, YY1-silencing suppresses the colonization and growth of A549-luc cells in lungs
Supplementary Movie 2 from Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer
Authors: Nobis Max , McGhee Ewan J. , Morton Jennifer P. , Schwarz Juliane P. , Karim Saadia A. , Quinn Jean , Edward Mike , Campbell Andrew D. , McGarry Lynn C. , Evans T.R. Jeffry , Brunton Valerie G. , Frame Margaret C. , Carragher Neil O. , Wang Yingxiao , Sansom Owen J. , Timpson Paul , Anderson Kurt I.
Published: April 2023

Supplementary Movie 2 - WMV file 935K, Mutant p53R172H PDACs expressing Src biosensor (green) invading in organotypic assay with SHG signal from ECM components (purple), z-section
Supplementary Methods and Materials from Cytomegalovirus Infection Leads to Pleomorphic Rhabdomyosarcomas in Trp53+/− Mice
Authors: Price Richard L. , Bingmer Katherine , Harkins Lualhati , Iwenofu O. Hans , Kwon Chang-Hyuk , Cook Charles , Pelloski Christopher , Chiocca E. Antonio
Published: April 2023

PDF file - 131K, Generation of Trp53+/- mice; Human samples; Virus preparation; HCMV in situ hybridization; HCMV DNA PCR and RT-PCR; Other statistical analysis
Supplementary Figure 1 from GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth In Vitro and In Vivo
Authors: Raab Marc S. , Breitkreutz Iris , Anderhub Simon , Rønnest Mads H. , Leber Blanka , Larsen Thomas O. , Weiz Ludmila , Konotop Gleb , Hayden Patrick J. , Podar Klaus , Fruehauf Johannes , Nissen Felix , Mier Walter , Haberkorn Uwe , Ho Anthony D. , Goldschmidt Hartmut , Anderson Kenneth C. , Clausen Mads H. , Krämer Alwin
Published: April 2023

PDF file - 60K, GF-15 does not induce spindle multipolarity in resistant cells
Supplementary Figure Legend from An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer
Authors: McCleland Mark L. , Adler Adam S. , Shang Yonglei , Hunsaker Thomas , Truong Tom , Peterson David , Torres Eric , Li Li , Haley Benjamin , Stephan Jean-Philippe , Belvin Marcia , Hatzivassiliou Georgia , Blackwood Elizabeth M. , Corson Laura , Evangelista Marie , Zha Jiping , Firestein Ron
Published: April 2023

PDF file - 95K
Supplementary Figure 2 from An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer
Authors: McCleland Mark L. , Adler Adam S. , Shang Yonglei , Hunsaker Thomas , Truong Tom , Peterson David , Torres Eric , Li Li , Haley Benjamin , Stephan Jean-Philippe , Belvin Marcia , Hatzivassiliou Georgia , Blackwood Elizabeth M. , Corson Laura , Evangelista Marie , Zha Jiping , Firestein Ron
Published: April 2023

PDF file - 257K, Animal weight change and tumor volume of individual xenograft tumors
Supplementary Figure 1 from An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer
Authors: McCleland Mark L. , Adler Adam S. , Shang Yonglei , Hunsaker Thomas , Truong Tom , Peterson David , Torres Eric , Li Li , Haley Benjamin , Stephan Jean-Philippe , Belvin Marcia , Hatzivassiliou Georgia , Blackwood Elizabeth M. , Corson Laura , Evangelista Marie , Zha Jiping , Firestein Ron
Published: April 2023

PDF file - 963K, Additional top targets from RNAi screen that are specifically required for triple negative breast cancer
Supplementary Figure 3 from STAT5 Is Crucial to Maintain Leukemic Stem Cells in Acute Myelogenous Leukemias Induced by MOZ-TIF2
Authors: Tam Winnie F. , Hähnel Patricia S. , Schüler Andrea , Lee Benjamin H. , Okabe Rachel , Zhu Nan , Pante Saskia V. , Raffel Glen , Mercher Thomas , Wernig Gerlinde , Bockamp Ernesto , Sasca Daniel , Kreft Andreas , Robinson Gertraud W. , Hennighausen Lothar , Gilliland D. Gary , Kindler Thomas
Published: April 2023

PDF file - 339K, LSC sorting strategy
Supplementary Figure 4 from Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression
Authors: Pazolli Ermira , Alspach Elise , Milczarek Agnieszka , Prior Julie , Piwnica-Worms David , Stewart Sheila A.
Published: April 2023

PDF file - 1MB
Supplementary Methods, Table 1, Figures 1-6 from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells
Authors: Brown-Endres Lauren , Schoenfeld David , Tian Fang , Kim Hyung-Gu , Namba Takushi , Muñoz-Fontela César , Mandinova Anna , Aaronson Stuart A. , Lee Sam W.
Published: April 2023

PDF file - 1.6MB, Table 1. Primers used for real-time PCR analysis of NF-kB target gene expression. Fig. S1. Recombinant human TNF�� rescues CDIP apoptosis in TNF�� knockdown cells. Fig. S2. TNF�� signaling was assessed in U2OS-CDIP cells 20 and 30 hours post-CDIP induction (dox), and 20 hours after treatment with 5 ng/mL recombinant human TNF�� (rhTNF��, boxed panel). Fig. S3. MAPK inhibitors do not block cell death induced by CDIP expression. Fig. S4. The NF-���� transcriptional program is altered in CDIP expressing cells. Fig. S5. The effects of IL-8 and ROS inhibition on CDIP��TNF�� apoptosis. Fig. S6. CDIP do not induce Fas.
Supplementary Table 8 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
Authors: Nikolaidis Georgios , Raji Olaide Y. , Markopoulou Soultana , Gosney John R. , Bryan Julie , Warburton Chris , Walshaw Martin , Sheard John , Field John K. , Liloglou Triantafillos
Published: April 2023

PDF file - 33K, Comparative detection efficiency of mSHOX2 and LLP methylation panel alone or in combination in the overlapping set of 236 samples
Supplementary Figure 1 from The Mixed Lineage Leukemia (MLL) Fusion–Associated Gene AF4 Promotes CD133 Transcription
Authors: Mak Anthony B. , Nixon Allison M.L. , Moffat Jason
Published: April 2023

PDF file - 78K
Supplementary Table 5 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
Authors: Nikolaidis Georgios , Raji Olaide Y. , Markopoulou Soultana , Gosney John R. , Bryan Julie , Warburton Chris , Walshaw Martin , Sheard John , Field John K. , Liloglou Triantafillos
Published: April 2023

PDF file - 38K, Coefficient and classification performance of top 6 univarite and best subset logit models in the training dataset