bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of integrating reinforcement learning and intelligent scheduling in logistics distribution
Authors: He Zhenhua , Chen Liang , Liu Bin
Published: February 2024

Logistics distribution is an indispensable part of the modern economy and is crucial for ensuring the efficient operation of the supply chain. With the continuous progress of technology, the application of intelligent scheduling systems in the field of logistics distribution is becoming increasingly widespread. Reinforcement learning, as one of the hot technologies in the field of artificial intelligence, is gradually receiving attention in its application in intelligent scheduling. Reinforcement learning can continuously learn and predict the same thing to enhance memory, while intelligent scheduling requires continuous prediction and optimization of logistics distribution paths. In response to the current problems of slow logistics distribution efficiency and low customer satisfaction, this article analyzed the application of intelligent scheduling in logistics distribution from the aspects of basic data maintenance, basic data review, intelligent scheduling, scheduling result review, distribution information management, and vehicle tracking. By using reinforcement learning, the traffic network weight in logistics distribution was studied to improve logistics distribution efficiency and customer satisfaction. This article analyzed the efficiency of logistics distribution, vehicle tracking accuracy, vehicle scheduling ability, and logistics distribution costs under different logistics distributions. The results showed that the logistics distribution under the integration of reinforcement learning and intelligent scheduling reduced 12.047 km compared to traditional distribution paths, and its distribution cost decreased by 129.718 yuan compared to traditional logistics distribution costs. The efficiency of logistics distribution that integrates reinforcement learning and intelligent scheduling has significantly improved, with optimized distribution costs and paths. It also has a positive effect on improving the utilization rate of logistics distribution vehicles.
Alzheimer DataLENS: An Open Data Analytics Portal for Alzheimer’s Disease Research
Authors: Noori Ayush , Jayakumar Rojashree , Moturi Vaishnavi , Li Zhaozhi , Liu Rongxin , Serrano-Pozo Alberto , Hyman Bradley T. , Das Sudeshna
Published: February 2024

Background: Recent Alzheimer’s disease (AD) discoveries are increasingly based on studies from a variety of omics technologies on large cohorts. Currently, there is no easily accessible resource for neuroscientists to browse, query, and visualize these complex datasets in a harmonized manner. Objective: Create an online portal of public omics datasets for AD research. Methods: We developed Alzheimer DataLENS, a web-based portal, using the R Shiny platform to query and visualize publicly available transcriptomics and genetics studies of AD on human cohorts. To ensure consistent representation of AD findings, all datasets were processed through a uniform bioinformatics pipeline. Results: Alzheimer DataLENS currently houses 2 single-nucleus RNA sequencing datasets, over 30 bulk RNA sequencing datasets from 19 brain regions and 3 cohorts, and 2 genome-wide association studies (GWAS). Available visualizations for single-nucleus data include bubble plots, heatmaps, and UMAP plots; for bulk expression data include box plots and heatmaps; for pathways include protein-protein interaction network plots; and for GWAS results include Manhattan plots. Alzheimer DataLENS also links to two other knowledge resources: the AD Progression Atlas and the Astrocyte Atlas. Conclusions: Alzheimer DataLENS is a valuable resource for investigators to quickly and systematically explore omics datasets and is freely accessible at https://alzdatalens.partners.org.
Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach
Authors: Dai Yulin , Hsu Yu-Chun , Fernandes Brisa S. , Zhang Kai , Li Xiaoyang , Enduru Nitesh , Liu Andi , Manuel Astrid M. , Jiang Xiaoqian , Zhao Zhongming ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: February 2024

Background:

The progressive cognitive decline, an integral component of Alzheimer’s disease (AD), unfolds in tandem with the natural aging process. Neuroimaging features have demonstrated the capacity to distinguish cognitive decline changes stemming from typical brain aging and AD between different chronological points.

Objective:

To disentangle the normal aging effect from the AD-related accelerated cognitive decline and unravel its genetic components using a neuroimaging-based deep learning approach.

Methods:

We developed a deep-learning framework based on a dual-loss Siamese ResNet network to extract fine-grained information from the longitudinal structural magnetic resonance imaging (MRI) data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study. We then conducted genome-wide association studies (GWAS) and post-GWAS analyses to reveal the genetic basis of AD-related accelerated cognitive decline.

Results:

We used our model to process data from 1,313 individuals, training it on 414 cognitively normal people and predicting cognitive assessment for all participants. In our analysis of accelerated cognitive decline GWAS, we identified two genome-wide significant loci: APOE locus (chromosome 19 p13.32) and rs144614292 (chromosome 11 p15.1). Variant rs144614292 (G > T) has not been reported in previous AD GWA studies. It is within the intronic region of NELL1, which is expressed in neurons and plays a role in controlling cell growth and differentiation. The cell-type-specific enrichment analysis and functional enrichment of GWAS signals highlighted the microglia and immune-response pathways.

Conclusions:

Our deep learning model effectively extracted relevant neuroimaging features and predicted individual cognitive decline. We reported a novel variant (rs144614292) within the NELL1 gene.
Vulnerability of Spatial Pattern Separation in 5xFAD Alzheimer’s Disease Mouse Model
Authors: Gephine Lucas , Roux Candice M. , Freret Thomas , Boulouard Michel , Leger Marianne
Published: February 2024

Background:

Alzheimer’s disease (AD) is the most common cause of dementia and remains incurable. This age-related neurodegenerative disease is characterized by an early decline in episodic and spatial memory associated with progressive disruption of the hippocampal functioning. Recent clinical evidence suggests that impairment of the spatial pattern separation (SPS) function, which enables the encoding and storage of episodic spatial information, may be an indicator of the early stages of AD.

Objective:

The aim of our study was to characterize SPS performance at a prodromal stage in 5xFAD transgenic mouse model of AD.

Methods:

Behavioral performance of male wild-type (WT) and 5xFAD mice ( n = 14 per group) was assessed from the age of 4 months in two validated paradigms of SPS function either based on spontaneous exploration of objects or on the use of a touchscreen system.

Results:

Compared with age-matched WT littermates, a mild deficit in SPS function was observed in the object recognition task in 5xFAD mice, whereas both groups showed similar performance in the touchscreen-based task. These results were observed in the absence of changes in locomotor activity or anxiety-like behavior that could have interfered with the tasks assessing SPS function.

Conclusions:

Our results indicate an early vulnerability of the SPS function in 5xFAD mice in the paradigm based on spontaneous exploration of objects. Our work opens up the possibility of examining the early neurobiological processes involved in the decline of episodic memory and may help to propose new therapeutic strategies in the context of AD.
A dense and U-shaped transformer with dual-domain multi-loss function for sparse-view CT reconstruction
Authors: Liu Peng , Fang Chenyun , Qiao Zhiwei
Published: February 2024

OBJECTIVE:

CT image reconstruction from sparse-view projections is an important imaging configuration for low-dose CT, as it can reduce radiation dose. However, the CT images reconstructed from sparse-view projections by traditional analytic algorithms suffer from severe sparse artifacts. Therefore, it is of great value to develop advanced methods to suppress these artifacts. In this work, we aim to use a deep learning (DL)-based method to suppress sparse artifacts.

METHODS:

Inspired by the good performance of DenseNet and Transformer architecture in computer vision tasks, we propose a Dense U-shaped Transformer (D-U-Transformer) to suppress sparse artifacts. This architecture exploits the advantages of densely connected convolutions in capturing local context and Transformer in modelling long-range dependencies, and applies channel attention to fusion features. Moreover, we design a dual-domain multi-loss function with learned weights for the optimization of the model to further improve image quality.

RESULTS:

Experimental results of our proposed D-U-Transformer yield performance improvements on the well-known Mayo Clinic LDCT dataset over several representative DL-based models in terms of artifact suppression and image feature preservation. Extensive internal ablation experiments demonstrate the effectiveness of the components in the proposed model for sparse-view computed tomography (SVCT) reconstruction.

SIGNIFICANCE:

The proposed method can effectively suppress sparse artifacts and achieve high-precision SVCT reconstruction, thus promoting clinical CT scanning towards low-dose radiation and high-quality imaging. The findings of this work can be applied to denoising and artifact removal tasks in CT and other medical images.
Penguatan Petani Aren Melalui Penerapan Business Model Canvas di Desa Alu Polewali Mandar
Authors: Wijayanti Andi Ridha Yayank , Idris Andi Irmayanti , Ramli Muhammad Agusfartham , Arafat Andi
Published: February 2024

Aren merupakan salah satu tanaman yang sangat potensial untuk dikembangkan. Di Desa Alu Polewali Mandar, salah satu pemanfaatan dari hasil aren yang banyak diusahakan petani adalah pembuatan gula merah. Sampai saat ini gula merah yang dihasilkan hanya dijual ke pengumpul atau dijual langsung pada pasar tradisional. Pengabdian ini bertujuan untuk pengutan kapasitas petani melalui pelatihan Business Model Canvas melaui  sembilan elemen kunci yang akan memberikan gambaran dan pandangan strategis kepada petani aren, membantu mereka mengidentifikasi sumberdaya apa saja yang dibutuhkan, serta melihat peluang dan risiko yang mungkin ditimbulkan. Metode pelaksanaan dalam kegiatan ini yaitu observasi permasalahan mitra melalui FGD, perencanaan dan persiapan, dan pelaksanaan kegiatan berupa pelatihan. Berdasarkan hasil pengabdian yang dilakukan melalui pendekatan Business Model Canvas dapat diidentifikasi terkait peningkatan usaha, diversifikasi produk dan perluasan pasar. Terkait pelaksanaan pengabdian petani sangat antusias dan berharap Business Model Canvas yang dibuat dapat digunakan menjadi landasan untuk merancang dan mengembangkan usaha gula aren mereka.
The cognitive and artistic value of Dulat Isabekov’s story «We Have Not Seen War»
Authors:   L.N. Gumilyov Eurasian National University, Korganbekov B.
Published: February 2024

Writer Dulat Isabekov’s novel «We Have Not Seen War» has not received much attention from critics and literary experts. There are a number of reasons for this. Despite the compact size of the work, there are reasons to talk about complex artistic applications, such as a large number of characters on the character level, the lack of a single storyline, the complexity of syntagmatics in the depiction of characters and the multi-layered nature of the genre prevented the literary analysis. Not only the protagonists of the story, but also the episodic characters have their characteristics. Through them the writer masterfully showed how people living in a Kazakh village shared the hardships of that time during the war and fought not only against the consequences of the war but also for the preservation of human values. Since the main theme is connected with the life of children of that time, the character of heroes who grew up before their peers lived in peacetime, takes a leading role in the subject matter of the work. In depicting these moments, the artistic contribution of parallelism and images antithesis was very strong. The author’s narrative and psychologism, the types of monologues and dialogues, and the actions of the characters are saturated with details that carry an ideological load. The emotional impact of the work is very strong; it is rich in lyrical intonations and meditative elements. The title of the story also acts as a montage phrase and subsequently becomes a leitmotif. The article reveals the trace of literary experience in the work, analyses the theme and idea of the work, the system of images, the nature of the conflict, its link with the plot, the role of representation components in the presentation of the idea, the author’s chronotope and artistic communication.
Diversity and Multiplicity of Fantasy Genre in Modern Literary Criticism
Authors:   L.N. Gumilyov Eurasian National University, Melnova K. , Ospanova Zh. ,   A.K. Kussayinov Eurasian Humanities Institute
Published: February 2024

Fantasy as a genre has a long and complex history of formation. The history of fantasy is as old as humanity itself. Its legitimate predecessors are a fairy tale, a novel and a fable. Fantasy aims to build up not only the realm of dreams, but also seeks to establish itself as a significant and indispensable system. The literary fantasy genre usually starts with obvious or concealed subtext about the existence of several realities and moves in the direction of awakening heroes’ previously unknown parts of themselves. The fantastical genre, having greater freedom in creating an image of the world, has the opportunity to defend and prove “in practice” the importance of eternal humanistic values. Many scientists disagree not only in defining fantasy as a type of literature, but also on its components. In order to determine similarities and differences between the existing theories of fantasy division, the main types of fantasy worked on by Kovtun, Shidfar, F. Mendlesohn and others are described using descriptive, comparative and other literary methods. All the scientists studied have been doing their research for the past hundred years, which gives a wide field for analysis. During the review of existing theories, it was revealed that the main elements of fantasy move from one classification to another, changing only the names.
Author’s Worldview in the Context of Gender Analysis of Literary Works (based on the Novel Green Tent by L. Ulitskaya)
Authors:   L.N. Gumilyov Eurasian National University, Nurgali K.
Published: February 2024

This article examines the features of the author’s concept of creating an artistic world in the context of gender issues, as the issue of «women’s writing» in the modern stage of literary studies is one of the relevant ones, as evidenced by the diversity of theoretical works considering feminist literature. The novel «Green Tent» by Lyudmila Ulitskaya was chosen as the object of study, as this author is one of the promising contemporary writers. The purpose of this study is to identify the features of the artistic world of the work from the point of view of the author’s positioning in the context of gender issues. To successfully achieve this goal, we collected material regarding “women’s writing” in the context of changes in the literary process, analyzed the novel of the author chosen as the object of study from the perspective of the use of various linguistic means and a comparative analysis of the character system: the differences and similarities of male and female types of characters in a work of art. In the course of the analysis, it was revealed that Ulitskaya uses the linguistic diversity of language, tropes and various connotations, detailed description of the system of characters, and social and axiological aspects of the described era to create an authorial picture of the world
Brief characteristics of proper names
Authors:   Central Asian Innovation University, Yerekhanova F. , Satylkhanova G. ,   M.Auezov South Kazakhstan State University, Zhorabekova A. ,   M.Auezov South Kazakhstan State University
Published: February 2024

Anthroponymy is indeed the study of anthroponyms, which are personal names given to individuals or groups of people. Understanding how to express the semantic features of personal names in dictionaries is crucial for accurately capturing and conveying the diverse meanings and cultural nuances associated with names. Thus, we have conducted a comprehensive study on anthroponymy, specifically focusing on the general characteristics of proper names briefly referring to some examples in Kazakh, British English, and American English. By consulting various works dedicated to anthropology and linguistics, we have likely gathered valuable insights into the anthroponymic systems of some cultures and languages. The use of tables and figures can be helpful in presenting and analyzing data related to the characteristics of names. Furthermore, our analysis of unisex proper names in Great Britain and Kazakhstan for the year 2023 adds a contemporary and specific dimension to the given research. Overall, this article appears to offer a brief exploration of personal names, incorporating general characteristics, cultural identity, and contemporary analysis. This descriptive approach is likely to provide readers with valuable insights into the types and trends of proper names in English-speaking countries and Kazakhstan.
Features of the development of environmental journalism in Kazakhstan
Authors:   Al-Farabi Kazakh National University, Maykotova G. , Abdraman Е. ,   Al-Farabi Kazakh National University, Ornykbay T. ,   Al-Farabi Kazakh National University
Published: February 2024

The article is devoted to the study of the formation and development of environmental media, which are considered a new and innovative area of journalism. The relevance of the study today lies in clarifying and evaluating the role of the media in shaping the deep attitude and culture of mankind toward ecology. Thus, attention should be paid to the creative nature of the environmental media in front of the public, which will determine the causes of environmental problems and their prerequisites.The purpose of the study is to analyze the stages of development and formation of environmental journalism by chronological years, drawing attention to comparative data and stories in modern domestic and foreign media. The content of the term “ecology” is very large and wide. Among them, the object of study will be researchers of domestic journalism and the work of professionals working in the field of journalism in the near and far abroad. In this regard, the article highlights not only the past and present of environmental journalism but also its first steps and features of public support
News agencies: content quality and target audience
Authors:   Al-Farabi Kazakh National University, Kultayeva S. , Zhaxylykbaeva R. ,   Al-Farabi Kazakh National University, Akynbekova А. ,   Al-Farabi Kazakh National University
Published: February 2024

Currently, news agencies are among the active players in the fight against the spread of false information. Reliable data on any news of importance can be found in the materials of major local or foreign news agencies. The reason for this can be explained by the professional and ethical responsibilities imposed on news agencies: they are responsible not only to their immediate audience, which is in most cases media representatives, but also to the audience of those media representatives.However, at the same time, it is interesting to think that news agencies also conduct their activities depending on the position and policy of the owner. In the article, an analysis of this opinion was carried out, and the results of a study aimed at determining the features of the current activity of information agencies, in general, were given.The main object of the research is the state Kazinform agency, however, for a comparative analysis, the activities of private Interfax-Kazakhstan and foreign, Dutch ANP agencies were reviewed, questions were sent to the editors of these agencies, and their answers were analyzed.In order to verify the thought that agencies, especially state ones, carry out propaganda, a review of the current general activity, audience and topics of the agencies was carried out, and their specific materials were analyzed.In order to verify the thought that not only the sources used by agencies, but also the activities and decisions of journalists and editors affect the audience’s reception of information, the concept of framing was analyzed based on real materials (published by Kazinform, Reuters). The analysis of the activities and content of agencies helps to understand how they are adapting to the situation in the current changing information and media market.
Hate speech and legal regulation in digital communication
Authors:   Al-Farabi Kazakh National University, Oshanova O.Zh. ,   Al-Farabi Kazakh National University, Kalibekuly D. , Elesheva A. ,   L.N. Gumilyov Eurasian National University
Published: February 2024

The article discusses the main characteristics of digital communication in the modern world and Kazakh society, as well as new transformations and forms of transmission of messages transmitted through digital communication.The digital media age makes any online chat or media product accessible with a single touch of the screen but makes it possible to share them without thinking about the consequences. In this regard, the article highlights the main advantages and harmfulness of intensifying and changing the exchange of information using modern technical means.As the number of media products on the Internet grows, so does the spread of hate speech. In this article, we identify and explore various ways to identify media products filled with hate speech on social networks. The problems and limitations we face in this direction also be mentioned. We also discuss the legal and practical aspects of resolving this issue.
Spiritual values in the journalism of saint Bekasyl
Authors:   L.N. Gumilyov Eurasian National University, Sakhov A. S. , Batyrbekkyzy G. ,   M. Auezov South Kazakhstan University
Published: February 2024

In the first half of the 19th century Kazakh people strictly observed the principles of the Islamic religion and the main traditions that are the basis of national identity. This helped to improve the national identity of the Kazakh people. But starting from the second half of the 19th year, the colonial policy of the tsarist government began to exert its negative influence on the Kazakh society. The current socio-political situation and the growing injustice in society have led to the manifestation of a new wave of protests. One of the outstanding personalities of that difficult time was Bekasyl Bibolatuly, who made a significant contribution to the development of the national identity of the Kazakh people. He got knowledge in the madrasah of Sayram, Karnak, Bukhara and Damascus. His goal was to selflessly and honestly serve his people. He searched and tried to find ways to solve problematic issues that arose as a result of that time’s policy. Thus, Bekasyl Aulie (Saint) paid special attention to education, opened a madrasah and taught children. He was concerned about many issues, such as people’s health, natural phenomena that have a negative impact on the activities of farmers. He left his accumulated knowledge and great legacy in the form of a manuscript.Based on the analysis of his work, written in 1323 Hijri and on the history stored in the people’s memory, we can state how Bekasyl Aulie strove for knowledge, goodness, the fight against people’s illiteracy, promoted high morality
The issues of national spirituality in Oralkhan Bokey’s journalistic works
Authors:   L.N. Gumilyov Eurasian National University, Tahan S.Sh. , Sirenova B.A. ,   L.N. Gumilyov Eurasian National University
Published: February 2024

The article looks into the ways the journalistic works by Oralkhan Bokey, while dedicated to contemporaneous topics, reflect on the forms of spirituality and existential experiences of the Kazakh people. The study sheds light on the significance of the sacred names of Abai and Makhambet in the structuring of national spirituality, and highlights how important the deep cultural symbolism of the customs coming from the distant historical past that are rooted in the present life of the people are for explaining their genetic code. Of particular interest is the highest esteem which Bokey the publicist expresses for the oratorical word of the Kazakh society in the past, which, in his understanding, is a national tradition of the spirit that should be carried into the future. The essayistic genre is proclaimed by Bokey as a translator of the people’s spiritual values, and a mirror of the internal world of a contemporary that reflects the latter’s new existential psychology. The essay as an effective form of art of the word and the central genre of journalism should continue the traditions of “kosemsoz”, the national journalism of the past, as a form of national spirituality. Bokey views journalism as belonging with literary fiction as a form of social consciousness, while literature improves its tools for reflecting and studying the collisions of the surrounding world in close contact with journalism.
The role of media communication in building a civil society
Authors:   International Information Technology University, Niyazgulova A.A. , Mukan S.M. ,   International Information Technology University
Published: February 2024

The article examines the influence of the media communication on the construction of civil society. The authors come to the conclusion that the presence of independent media is important, but not a sufficient factor for the emergence and development of civil society. The article also highlights the influence of information technologies (IT) for manipulating public opinion on the political behavior of the masses as well as decision makers so far. In the XXI century, the role of the media in the world has greatly increased, where they have great influence on politics and are therefore presented as a source of power. The media can control power and the opposition, trying to make all their activities transparent. Thus, the media communication today is also a large corporation employing people who promote democratic values, but in totalitarian countries the media is still under direct control government. Technological development has brought about a great revolution in social life, and this development has not left aside the media and other forms of human communication.
Machine learning for effective EHR management in blockchain-cloud integration
Authors: Saraswat Birendra Kumar , Saxena Aditya , Vashist P. C.
Published: February 2024

Machine learning (ML) techniques have gained prominence in effectively managing Electronic Health Record (EHR) systems within the context of blockchain-cloud integration. This study presents a hybrid Machine Learning approach that combines logistic regression (LR) and random forest (RF) techniques for EHR management, leveraging the data stored in a blockchain-cloud integrated system. The tamper-resistant nature of blockchain ensures the authenticity and security of the stored patient information, serving as a reliable source for learning. The proposed LR+RF model is evaluated against other algorithms, considering various performance metrics. The analysis reveals that the LR+RF model achieves an impressive accuracy rate of 98.37%, indicating its efficacy in accurately classifying EHR data and facilitating effective management. Furthermore, the study compares the performance of blockchain-cloud-based decentralized storage with blockchain-based storage and peer-to-peer storage in terms of latency and throughput. The results demonstrate that the blockchain-cloud integrated decentralized storage surpasses other storage methods, achieving an average throughput of 6.8 units and a latency of 4.7 units. These findings highlight the potential of the proposed LR+RF model for EHR management within a blockchain-cloud integrated environment. The use of blockchain as a secure storage environment ensures the integrity of patient information, while Machine Learning techniques enhance the accuracy of classification.
Fingerprint based authentication framework for IoT environment
Authors: Singh Vijender , Kant Chander
Published: February 2024

Internet of Things (IoT) approach makes the humans life easy and safe and due to its acceptability and portability. Humans are surrounded by multitude of heterogeneous devices which assist them in their daily routine. The integration of Blockchain technology with IoT played an important role in medical science and online transaction. At same point of time, the IoT network and devices are vulnerable that can be exploit to affect the network and devices security and accessibility. Therefore, robust authentication techniques should be implementing to secure the IoT network as well as devices accessibility. Due to high heterogeneity of applications, providing authentication for these devices is always challengeable. In this work, a novel fingerprint-based authentication framework in implemented in which Gaussian filter is used for image smoothness, Robert filter for edge detection and achieve 94% accuracy while authentication.
Mesenteric small cell lymphocytic lymphoma presenting as acute intestinal obstruction: A rare case scenario
Authors: Singh Anurag , Sharma Puneet , Gupta Ayushya , Thakur Nancy
Published: February 2024

Small-cell lymphocytic lymphoma is a rare type of B-cell non-Hodgkin lymphoma. It is known as one of the indolent lymphomas. Moreover, sigmoid volvulus as an initial presentation is extremely uncommon. We encountered a unique case of mesenteric small cell lymphocytic lymphoma that presented with sigmoid volvulus as the initial clinical presentation. A 55-year-old male presented with 7-day history of abdominal pain, abdominal distension for 6 days, and non-passage of stool and flatus with recurrent vomiting for 3 days. Abdominopelvic computed tomography revealed a distended small bowel with volvulus of sigmoid colon with twisting of its mesentery with inter-ileal as well as free peritoneal collections of fluid. A manual untwisting counterclockwise of the volvulus followed by resection and anastomosis at a point where the bowel has apparent normal thickness and color along with excisional biopsy of the enlarged lymph node. Histopathology confirmed the diagnosis of small-cell lymphocytic lymphoma. Mesenteric lymphomas are less likely to present with sigmoid volvulus as the initial clinical presentation due to their extraluminal location and also they are indolent in course. Early diagnosis and its management reduce morbidity and mortality.
Turning the young and healthy patient into an elderly faster: A cascade of complications related to immobility
Authors: Batista Filho Luiz Alberto Cerqueira , Pacheco Junior Mario Correa Netto , Maciel Alexandre Toledo , Medeiros Larissa Seraphim
Published: February 2024

A 42-year-old individual presented with a ruptured left patellar ligament after playing basketball. After undergoing reconstructive orthopedic surgery, he sustained a posterior shoulder dislocation while using crutches, necessitating additional surgery. This combination of orthopedic injuries rendered the patient immobile and bedridden for several months, and immobility-related complications began to develop. Immobilism is a condition that physicians typically associate with elderly and neuropathic patients; however, little is said about this pathology when young and healthy patients who have experienced acute diseases are considered. With a review of the relevant literature, this article describes a peculiar succession of immobility-related complications.
Unusual hard palate swelling in an infant: A case of impacted pistachio shell
Authors: Shruthi Muppidi , Kantala Santhosh Reddy , Mandali Satish , Burli Pradeep
Published: February 2024

Children are prone to foreign body aspiration. Impaction of foreign bodies in the hard palate is a rare phenomenon. We present a case report where the infant’s palatal swelling was mistaken for a tumor or cyst and was planned for excision and later turned out to be an impacted pistachio shell. We emphasize considering the foreign body as a differential diagnosis in children who present with unusual hard palate mass.
Rectal MiNEN: A rare case report
Authors: Sharma Jagannath Dev , Suhana Asreen , Beso Adahra Patricia , Bharadwaj Barasha S , Deka Muktanjalee , Kalita Upasana , Goswami Bibhash Chandra
Published: February 2024

Rectal mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) are rare tumors with two components, neuroendocrine and non-neuroendocrine, each comprising 30% of all tumors. There have been limited studies on the epidemiology, clinical and prognostic characteristics of these tumors. Here, we report a case series of two cases of rectal MiNEN from a tertiary care center in North East India. These tumors are known to be aggressive and often with poor prognosis.
Antifungal and antibacterial activity of the extract from the fruit of Aiouea trinervis Meisn. (Lauraceae)
Authors: Menezes Filho Antonio Carlos Pereira de
Published: February 2024

Aiouea trinervis is a Brazilian shrub species of the Lauraceae family. In this study, the antifungal and antibacterial activity of the hydroethanolic extract 70% of the fruit of A. trinervis on the genus Candida, Staphylococcus and Salmonella sp. was evaluated using the paper disk diffusion method. Antifungal activity was observed for C. albicans (7-4 mm) and C. tropicalis (11-3 mm), and in the antibacterial test for S. aureus (9-2 mm) and S. serovar Enteritidis (14-4 mm) in concentrations greater than 50 mg mL-1 of the hydroethanolic extract of the fruit. The results confirm the potential antifungal and antibacterial activity of the hydroethanolic extract of the fruit of A. trinervis.
ШЛЯХИ ПІДВИЩЕННЯ ЕФЕКТИВНОСТІ УПРАВЛІННЯ МОРСЬКИМИ ПЕРЕВЕЗЕННЯМИ В СУЧАСНИХ УМОВАХ
Authors: Головченко Олена
Published: February 2024

У статті досліджено теоретичні і методологічні аспекти управління морськими перевезеннями у сучасних умовах глобальної економіки, розглянуто значення морських перевезень як ключового компонента світової торгівлі та економічного розвитку, проведено аналіз сучасного стану морських перевезень та визначення шляхів підвищення їх ефективності. Виділені основні виклики і труднощі, з якими стикається галузь морських перевезень, тенденцій розвитку морської транспортної системи та її вплив на світову економіку, визначені аспекти, які найбільше впливають на ефективність управління морськими перевезеннями. Розглянуто використання передових технологій в морському транспорті, можливості автоматизації та використання штучного інтелекту в процесах управління морськими перевезеннями. Досліджено можливості використання екологічно чистих технологій у морському транспорті. Розглянуто впровадження ефективних систем комунікацій у сфері управління морськими перевезеннями, та можливості співпраці між країнами у сфері морського транспорту для оптимізації міжнародних логістичних ланцюгів. Досліджено перспективи розвитку галузі на основі виявлених тенденцій та інновацій. Запропоновані шляхи підвищення ефективності управління морським транспортом.
ЦИФРОВА ТА ФІНАНСОВА ІНКЛЮЗІЯ МІЖНАРОДНИХ МІГРАНТІВ В ПРИЙМАЮЧИХ КРАЇНАХ
Authors: Шепель Олександра
Published: February 2024

Цифровізація призвела до розробки нових продуктів, платформ і послуг, а також підсилила попит трудових мігрантів до більшої кількості джерел інформації, навчальних ресурсів та онлайн-послуг. Цифровізація надає країнам можливість залучати кращих працівників з-за кордону, розгортати портали електронного урядування та навчати громадян, щоб переконатися, що вони мають відповідні цифрові навички, щоб скористатися перевагами цифрової революції, що триває, визнаючи навички та кваліфікацію громадян третіх країн. У цій статті на прикладі конкретних країн проаналізовано тенденції щодо запровадження цифрових продуктів та послуг, які сприяють трудовій міграції та полегшують інклюзію мігрантів в суспільство приймаючої країни, виявлено переваги від переходу на онлайн-сервіси в державному секторі та під час переказу грошових коштів у країну походження, а також перешкоди для використання сучасних технологій мігрантами, висвітлено існуючі заходи і подальші рекомендації використання цифрових технологій та онлайн-послуг задля полегшення адаптації та інтеграції мігрантів у середовище приймаючих країн. Ефективна імплементація цифрових продуктів може підвищити ефективність державного сектору, пришвидшивши економічні процеси та зменшити час працівників, який вони використовують на бюрократичні процедури.
The Chemometric Approach for Verification of Paracetamol Level in Pharmacies Products Using Spectrophotometer UV-Vis
Authors: Munir Muhammad Abdurrahman
Published: February 2024

The objective of this study is to inspect paracetamol levels in Indonesian pharmacies and whether the level of paracetamol is matched the label given. The verification of paracetamol level using a chemometric approach such as partial least squares (PLS) and principal component regression (PCR) after measured with spectrophotometer UV. The outcome of this study showed the absorbance at 242 with an R2 (0.9991) and the linear range at 1.0 – 6.0 μg·mL-1. The accuracy was satisfactory and obtained at 99.18%. The satisfactory outcomes revealed the identification method has a good potential to be used in inspecting the paracetamol level in pharmaceutical products. Furthermore, the chemometric method used as a statistical measurement showed that there was no specific distinction to the validated approach. Thus, this approach can be applied in pharmacy industries specifically for small industries to ensure the medicine's safety before being distributed to the pharmacies.
Analysis of Underwriting Procedures in Minimizing the Occurrence of Surety Bond Claims in the Perspective of Sharia Insurance
Authors: Fitrah Al Tasya , Soemitra Andri , Gultom Mitra Sami
Published: February 2024

A surety bond is a type of liability to bear the consequences of a non-performance of the principal in a construction contract as a form of guarantee to protect the interests of the oblige or the user of the service in the project drive work. The purpose of this research is to provide information on how an Underwriter performs Underwriting Procedures in minimizing the occurrence of Claims on Surety Bonds in PT. Public Insurance Bumida 1967 Field Branch. The method used by the Miles and Huberman techniques is the collection of data from interviews and literary studies. The results of this research show that the procedure used by underwriters in minimizing the occurrence of claims based on applicable company terms by analysing using the 5C method, conducting training of assurance analysis teams and holding risk monitoring. The claim arises due to the existence of a non-performance, which then obligee formally terminate the employment relationship with the Principal, Obligee will file the claim with the Guarantor Company. In Islamic view, surveillance and risk analysis are permitted, but in this procedure the principle of help is eliminated, the investment of funds of any sector, and the occurrence of gharar, in this agreement is prohibited in the principles of Shariah. On the other hand, underwater purposes to preserve and preserve the authenticity of the treasury.
Softskill Training , Outbound Training And Knowledge Sharing On The Performance Of Perumdam Tirta Hita Buleleng Employees
Authors: Yudi Prastiwi Ni Luh Putu Eka , Didiet Prayogo Nyoman , Ni Made Sri Ayuni , Widnyani Ni Made
Published: February 2024

This test has results to see whether soft skill training , outbound training, along with knowledge sharing have an impact on the performance of Tirta Hita Buleleng employees. This test was carried out at the Tirta Hita Buleleng Regional Drinking Water Company. The population used in this test is all employees who work at Perumdam Tirta Hita Buleleng, namely 75 employees. The rating scale uses a Likert scale which then the data obtained is processed using multiple linear regression analysis techniques. in this test the findings obtained were 1) the more consistent the soft skill training was , the more employee performance at Perumdam Tirta Hita Buleleng 2) the more consistent outbound training was carried out regularly, resulting in increased employee performance at Perumdam Tirta Hita Buleleng. 3) The more knowledge sharing is carried out , so that the performance of employees at Perumdam Tirta Hita Buleleng increases.
The Impact Of Human Capital Quality, Public Health, Education Quality, And Public Services On Governance, All Of Which Have Implications For Community Well-Being
Authors: Siregar Budi Alamsyah , Suma Dewi , Ichsan Reza Nurul
Published: February 2024

The objective of this study was to assess the impact of human resource quality, public health, education quality, and public services on governance, which has an impact on community welfare. A random sampling approach was used to randomly select 330 respondents. Questionnaires were used to collect data. SEM-PLS with structural equation modelling (SEM) was used for data analysis. Based on the findings of the study, the quality of human resources, public health, quality of education, public services, and governance all have a significant impact on community welfare. These five research variables are prioritised for improvement. The quality of human resources, public health, education, and public services show useful results, which can be a solution to welfare problems to achieve good governance, as long as they are within the framework of improving community welfare and not exploiting them for other personal gains. This research also shows the importance of the Muara Enim Regency government in preventing corrupt practices, especially since corrupt practices have a significant impact on people's welfare, because they not only make administrative procedures slow, expensive, and inefficient, but also divert resources to local governments. The Muara Enim Regency Government is expected to be able to equip its people with quality human resources, health services, public education, and public services, resulting in superior governance. This research also proposes that the Muara Enim Regency Government be more successful in making policies to stay on track and improve the human development index.
Factors that Influence the Caring Behavior of Nurses in Nursing Practice at the Hospital. Dr. MM Dunda Limboto
Authors: B. Syukur Sabirin , Yunus Pipin , Rajib Kasim Vidrian
Published: February 2024

Caring behavior can be shown in interpersonal relationships, namely relationships that occur between nurses and patients, where nurses show caring perception behavior through attention, interventions to maintain patient health, and positive energy given to patients. Nurses' caring behavior has started to be good, but there are still some nurses whose caring behavior is bad The purpose of this study is to analyze the factors that influence nurses' caring behavior in nursing practice at the hospital. Dr. MM Dunda Limboto. The design of this study is an Analytical Observational study with a cross-sectional approach. This research was carried out at RSUD. Dr.MM Dunda Limboto. The number of samples was 39 people. The results of the chi-square analysis test research obtained a p-value of  < α 0.00, so it can be concluded that there is a relationship between knowledge to nursing caring behavior, and there is a workload relationship to nurse caring behavior There is, there is an environmental relationship to nurse caring behavior. The existence of this research is expected to increase and increase nurses' awareness of caring behavior so that health services can be carried out effectively. It is recommended that this study be a reference for improving caring services for nurses and other health workers
Application of Markerless Augmented Reality on E-Catalog of Car Variations Using Natural Feature Tracking
Authors: Khouw Stevens , Edy
Published: February 2024

Information technology is widely used by business people in promoting the products and services they sell, this is very important especially for businesses that sell products that are not common, for example car variations. Car variation business is already widely found in various regions in Indonesia, but the car variation business has a relatively small and specialized market. The main cause is the lack of promotion of product knowledge to the public and the lack of interesting and practical forms of promotional media that make car variation products rarely seen by vehicle owners. Therefore, in this study, attempted on the application of augmented reality technology into the e-catalog application of car variations using the natural feature tracking method to help the visual augmentation process of car variation products that want to be seen as a form of promotional media for car variation products in general, the e-catalog itself were made using unity engine. From this research, the results obtained are: the application of augmented reality was successfully carried out on the Android e-catalog application, the attractiveness of the application display with a good indicator of 100%, the attractiveness of augmented reality with a percentage of 88.9% on good indicators and the appropriateness of application development with a percentage of 100% on good indicators, these result are obtained from questionnaires that are distributed to both coworker and random users as sample.
Designing Prototype of Volume Detector for Medical Oxygen Cylinder Using NodeMCU ESP8266
Authors: Mansur Mamad Muhamad , Ibrahim Rahmat Ismatullah , Budiman Ade Surya
Published: February 2024

The COVID-19 pandemic posed significant challenges to the healthcare sector, particularly due to the imbalance between patient numbers and available medical staff, resulting in difficulties during emergencies. One such challenge was the prompt replacement of oxygen cylinders. Leveraging Internet of Things (IoT) technology, we developed a prototype oxygen cylinder volume detector aimed at providing early notifications to healthcare professionals. This prototype incorporates the NodeMCU ESP8266, equipped with an Infrared (IR) Obstacle Sensor. The sensor communicates with a relay to activate an MP3 module, delivering audible alerts. Furthermore, the NodeMCU ESP8266 system integrates CTBot to send text notifications through the Telegram application to the nearest healthcare personnel. Visual alerts are also provided through red LED lights attached to the cylinders, indicating which oxygen cylinder is approaching depletion. Comprehensive testing validated the proper functionality of all system components. This innovative oxygen cylinder detector prototype is designed to streamline healthcare worker and nurse workflows by offering quicker access to accurate information regarding the status of medical oxygen cylinders. Not only does this enhance patient care efficiency, but it also ensuring the availability of oxygen is crucial for critical patients.