bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Discretization on the Speed Gradient Synchronization Control
Authors: Shagniev O. B. , Fradkov A. L.
Published: February 2023

Increasing the productivity of technological operations is a current task of modern science. The introduction of modern industrial equipment control systems is associated with the digitalization and computerization of enterprises. Vibration technology is one of the common types of industrial equipment used for screening, crushing, vibratory movement, etc. The energy approach for the vibration setups control makes it possible to keep a constant level of total energy of vibration setup oscillations, which makes it possible to develop intelligent control system under conditions of uncertainty in the parameter space. This paper is devoted to the study of the influence of digitalization and discretization on the speed gradient algorithm operation for the multiple synchronization control of vibration setup rotors and evaluation of the critical sensor signals sampling steps. The paper presents the results of numerical simulation based on the system dynamics equations and approximate values of vibration setup parameters. The simulation results present that an increase of the discretization sampling step leads to a disruption of the multiple synchronization mode up to the stability loss. The results of an experimental study on a mechatronic vibration setup SV-2M demonstrate in normal operation mode the low-frequency oscillations of the rotors speeds and the total system energy, which frequency is determined by the control signal limit. When the discretization step increase, the motion with stops is observed, which has a similar nature with the stable relaxation self-oscillations. The practical relevance of the obtained results is a detection of possible effects that occur in the system with significant discretization steps. Further development of adaptive control systems can be aimed to compensating of the discretization effect on the operation of the speed gradient control of the vibration setup rotors synchronization.
Optimization of the Course Movement of an Unmanned Vehicle in the Presence of Obstacles and Disturbances
Authors: Kabanov S. A. , Kabanov D. S. , Mitin F. V.
Published: February 2023

The article discusses the optimization of the control process of an unmanned vehicle. Currently, there is an active development and use of unmanned vehicles. There is a practice of using unmanned shuttles in closed areas (conferences, forums, etc.). The use of cars with automated control in urban conditions and on rough terrain is being tested. In this regard, it is important to develop control algorithms that allow solving problems of car control in real time under the influence of disturbances and the presence of obstacles. With the development of technology and an increase in computing power, it becomes possible to use optimal control algorithms that allow you to achieve better results when the terminal conditions are met, minimizing energy costs. This paper shows the solution of the problem of optimal control of an unmanned vehicle in the presence of a penalty function, measurement noise and disturbances from incomplete data using the separation principle. The problem of optimal control in a deterministic and stochastic setting is solved using an algorithm with a predictive model with a generalized work functional. The effectiveness of applying the Kalman filter is shown depending on the different intensity of measurement noise and different vehicle speeds. The results of numerical modeling are presented, showing the possibility of using the proposed algorithm to control an unmanned vehicle under various initial and final conditions. The developed algorithm has been successfully applied to bypass a moving object.
MELATONIN IMPROVES SPLEEN HISTOPHYSIOLOGY OF RATS WITH DIET-INDUCED OBESITY: CHRONOTHERAPY APPROACH
Authors:   Taras Shevchenko national University of Kyiv, Kalmukova Olesia , Shemetova Hanna ,   Taras Shevchenko national University of Kyiv, Skrypnyk Nataliia ,   Taras Shevchenko national University of Kyiv, Savchuk Olexiy ,   Taras Shevchenko national University of Kyiv, Dzerzhynsky Mykola ,   Taras Shevchenko national University of Kyiv
Published: February 2023

One of the most commoncharacteristics of obesity is the development of a systemic low-grade proinflammatory state in the entire body, including the immune organs. Spleen enlargement during diet-induced obesity contributes to the development of chronic inflammation. Melatonin due to immunomodulatory, antioxidant, and systemic metabolic rolesis proposed to be an effective candidate for anti-obesity therapy. As immune systems demonstrate pronounced circadian rhythmicity and immune cells have different types of melatonin receptors, a chronotherapeutic approach might be used to choose the most effective regimes of melatonin administration for the correction of obesity-provoked damage to the spleen. Thus, the main goal of our research was the analysis of the rats' spleen histophysiology during the development of high-calorie diet-inducedobesity (HCD) after administering melatonin daily at different times (morning or evening). Melatonin was administered by gavage for 7 weeks in the dose of 30 mg/kg 1 h before lights-off (HCD ZT11, M ZT11, evening), or 1 h after lights-on (HCD ZT01, M ZT01, morning). For assessment of the morpho-functional state of the spleen,the histopathological evaluation of red and white pulp in different zones of lymphoid follicles was implemented. It was observed that obesity development wasaccompaniedbyhyperemia and vessel dilatation in the red pulp; while in the white pulp notable deformation of germinal centers and destroyed borders between zones of lymphoid follicles were noticed.The HCD group demonstrated a decrease inthe relative amount of the white pulp, the crosssectional area of germinal centers, and the cross-sectional area of the marginal zone; whilethe increased relative amount of red pulp and marginal zone/germinal centers ratiowere detected compared with control. Melatonin administration to obese rats increases the relative amount of the white pulp (HCD ZT11 group), the cross-sectional area of germinal centers (HCD ZT01 and HCD ZT11 groups), and the cross-sectional area of the marginal zone (HCD ZT11 group), and decreasesmarginal zone/germinal centers ratio (HCD ZT01 group) in comparison with the HCD group.Also,it was demonstrated that a choice between the morning or evening regimes of the melatonin treatment did not affect the histophysiology of the spleen in rats receivingthe standard diet (M ZT01 and M ZT11 groups). These results indicate that melatonin can be considered to be a powerful potential therapeutic agent for the amelioration of obesity-induced changes in the spleen.
THE FUNCTIONING OF THE UKRAINIAN LANGUAGE IN THE CONDITIONS OF FULL-SCALE AGGRESSION BY RUSSIA AGAINST UKRAINE
Authors:   Research Institute of Ukrainian Studies Ministry of Education and Science of Ukraine, Kyiv Ukraine, BEZSMERTNA Natalia
Published: February 2023

The functioning of the Ukrainian language in the conditions of full-scale Russian aggression against Ukraine is analyzed. It was revealed that after February 24, 2022, the language issue became relevant in Ukrainian society, as Russian aggression contributed to the process of Ukrainization and the return of lost positions to the Ukrainian language in all spheres of society. It was found that, according to sociological surveys, there is a constant decrease in Russian-speaking Ukrainians and an increase in Ukrainian-speaking citizens. It was established that only the Ukrainian language should be used in public space, and the transition to the Ukrainian language should take place gradually, but purposefully. It has been observed that the first level of stabilization of language stability was made by language legislation, namely the Law of Ukraine "On Ensuring the Functioning of the Ukrainian Language as a State", which entered into force on July 16, 2019, and during 2019-2022 was gradually introduced into all spheres of Ukrainian society . It is justified that its implementation helped the Ukrainian language to regain its rightful place in the Ukrainian state, it should be noted separately that on July 16, 2022, separate norms of the language law entered into force, which established the status of the Ukrainian language in the information and business spheres. It was revealed that the second level of language stabilization is the Ukrainian government, which, using legislative, executive and judicial bodies, will implement and improve language legislation. It has been proven that the third level of language stabilization is the citizens of Ukraine, both ethnic Ukrainians and representatives of other nationalities, who can and should influence language stability. It is well-founded that returning the Ukrainian language to its proper status in the Ukrainian state in all areas of its life will help unite the Ukrainian political nation and motivate to defeat the Russian aggressors.
Power Consumption and Carbon Emission Equivalent for Virtualized Resources – An Analysis
Authors: G Anusooya , K Sathyarajasekaran , S Bharathiraja , M Braveen , M Premalatha
Published: February 2023

The International Energy Agency (IEA) revealed that the worldwide energy-related carbon dioxide (CO2) situation has hit a historic high of 33.1 Giga tonnes (Gt) of CO2. 85% of the rise in emissions was due to China, India, and the United States. The increase in emissions in India was 4.8%, or 105 Mega tonnes (Mt) of CO2, with the increase in emissions being evenly distributed across the transportation and industrial sectors, according to Beloglazov et al (2011). Environmental contamination brought on by carbon emissions is harmful to the environment. As a result, there is an urgent need for the IT sectors to develop effective and efficient technology to eliminate such carbon emissions. The primary focus is on lowering carbon emissions due to widespread awareness of the issue.
Ecological Capacity of Territory: Historyof Study, Review of Methods of Determination
Authors: Kopylov I.S. , Krasilnikov P.A. , Kletskina O.V.
Published: February 2023

The information about the concept of "ecological capacity of the territory", the history of the study of this area and an overview of the methods of its definition are provided.
Periodontal Ligament Fibroblast Cell Viability Following Treatment with Different Concentrations of Green Tea, Aloe Vera and a Mixture of their Extracts
Authors: Alavi Seyed Hamed , Rezvani Gita , Esfahani Mahmoud Nasr , Nobakht Lahrood Fatemeh
Published: February 2023

Objectives: Various studies have identified green tea and Aloe vera as a suitable medium for avulsed teeth. The aim of this study was to evaluate and compare the viability of periodontal ligament (PDL) fibroblasts following treatment with the extracts of these two plants and their mixture.
Materials and Methods: Human PDL fibroblasts were purchased and treated with different concentrations of Aloe vera, green tea, and a combination of these two extracts. Hank’s balanced salt solution and culture medium were employed as positive and negative controls, respectively. Viability was assessed using the MTT assay. Two-way ANOVA and post-hoc tests were used for statistical analysis (P<0.05).
Results: There was a significant difference in PDL fibroblast viability between different concentrations of the extracts. Higher concentrations of green tea and the combination of the two extracts significantly increased cell viability. Higher concentrations of Aloe vera had the least positive effect on maintaining the viability of these cells.
Conclusion: If confirmed by further studies, the combination of Aloe vera and green tea extracts might be considered as a suitable media for different purposes like storing avulsed teeth.
Bone Metabolism Parameters in Azerbaijani Pre and Postmenopausal Women with Diabetes
Authors: Safarova Sain Sattar
Published: February 2023

Background: This study aimed to determine the directionality of changes in serum bone remodeling markers and bone mineral density in the pre- and postmenopausal women with diabetes mellitus.
Methods: This study was carried out during the years 2016–2017 on the basis of Azerbaijan Medical University and included 142 pre- and postmenopausal women with type 1 and 2 diabetes mellitus (DM 1and DM2) were compared with 43 age-matched non-diabetics. The groups evaluated Ca2+, PTH, CT, 25(OH)D levels, serum bone remodeling markers (ALP, P1NP, b-CTx), lumbar spine, proximal and femoral neck areas using DXA assessment.
Results: The results showed inconsistency observed between bone remodeling processes in women with diabetes. A negative correlation was observed between duration of diabetes and Lumbar T-scores (DM1: r = -0.568, P = 0.001; DM2: r = -0.267, P = 0.04). Lumbar T-scores was negatively correlated with b-CTx level (DM1: r = -0.452, P = 0.002; DM2: r = -0.357, P = 0.09). Postmenopausal groups with DM1 and DM2 were slightly higher b-CTx levels than premenopausal.
Conclusion: The patients with DM2 compared to DM1 had higher average BMD at all measured areas. Bone fragility is the result not so much of a decrease in BMD, but alterations in bone microstructure, as indicated by the disregulation of bone remodeling markers. This suggests that patients with diabetes are at a higher risk of bone turnover disorders compared to individuals without diabetes, which does not necessarily correlate with differences in BMD.
The Effect of Hypertension, Diabetes, and Hyperlipidemia on Medication Intake and Adherence: Analysis from Korean Health Panel Survey 2014-2017
Authors: Park Jongho , Kim Yeaeun
Published: February 2023

Background: Hypertension, diabetes, and hyperlipidemia are common chronic diseases in South Korea, and medication is a key factor in managing these diseases and preventing disease advancement to multimorbidity. This study aimed to evaluate the effect of chronic disease on medication intake and adherence among Koreans.
Methods: This study was conducted utilizing data collected from 5,529 individuals that participated in the Korea Health Panel Survey (KHPS) in 2014-2017. The dependent variables were medication intake and adherence, and independent variables included socioeconomic status and the type of chronic disease. The differences in the medication intake and medication adherence by sociodemographic variables and the type of chronic disease were analyzed by chi-square test. The effect of hypertension, diabetes, and hyperlipidemia on medication intake and adherence was analyzed via multiple logistic regression using SAS statistical software.
Results: The rate of medication intake and adherence were significantly different among patients with hypertension, diabetes, and hyperlipidemia, especially lower in patients with hyperlipidemia compared to those with hypertension and diabetes. In multiple logistic regression analysis, the probability of medication intake increased in female gender, older age, medical aid, medication adherence was higher in married, lower educational level and lower household income. Compared to hyperlipidemia, patients with hypertension and diabetes had more likely to take medication as prescribed.
Conclusion: The importance of considering the type of chronic disease in developing and implementing public health programs aiming for improved medication adherence. Targeting better medication intake and adherence for each chronic disease could be a valuable policy strategy to effectively manage chronic diseases as well as prevent their complications.
Relevant Risk Factor and Follow-Up of Lung Nodules in Physical Examination with Low-Dose CT Screening
Authors: Wang Shucai , Xu Fang , Wang Yanfang , Wen Han , Wang Mo , Yuan Caixin , Xu Xiaoli , Du Yaqiang
Published: February 2023

Background: We aimed to explore the risk factors of lung nodules and lung cancer in physical ex-amination population with low-dose multi-slice spiral CT (LDCT) screening, to provide basis for lung cancer screening and follow-up management after CT examination.
Methods: The general data, serum tumor markers and CT images of 2,274 patients underwent LDCT in the Physical Examination Center of the Fourth Hospital of Hebei Medical University, China in 2019 were retrospectively analyzed and followed up for three years.
Results: The detection rate of lung nodules was 48.42%. The detection rate of lung nodules was higher in females, those over 70, those with history of smoking, passive smoking, drinking, precious history of lung diseases and family history of malignant tumors, with statistically significant differences (P<0.05). The abnormal rate of serum tumor markers (CA199, CA125 female and CYFRA211) were higher than that in the non-nodule group, with statistically significant differences (P<0.05). Multivariate logistic regression analysis showed that gender, age, history of smoking, passive smoking, family history of malignant tumors and serum tumor markers (CYFRA211 and CA199) were independent risk factors for the occurrence of lung nodules.
Conclusion: Gender female, age>35, history of smoking, passive smoking, history of drinking, history of past lung disease, family history of malignant tumors, abnormal CYFRA211 tumor markers were detected and low dose multi-slice spiral CT image showed ground-glass nodules are risk factors for lung nodules and lung cancer, which should be paid close attention to during physical examination and follow-up.
Factors Associated with Self-Rated Health among Korean Elderly
Authors: Jun Jeehye , Park Dahye
Published: February 2023

Background: South Korea has the fastest growing aging population in the world, and the Korean older adult population has been reported to have poor self-rated health (SRH). This cross-sectional descriptive survey aimed to examine the SRH and associated factors among the Korean older adult population using the 2019 Korea National Health and Nutrition Examination Survey (KNHANES) data.
Methods: The differences in SRH according to socioeconomic, health-related, and mental health-related factors and their relationships were analyzed using chi-square tests and logistic regression, using data from 1,521 older adults in Korea from the 8th KNHANES.
Results: Self-rated health was higher among older adults with a high family income (odds ratio [OR]=1.58, 95% CI: 1.05−2.36), those who finished elementary school or lower as opposed to those with a middle school diploma (OR=0.52, 95% CI:0.29−0.95), those with a low body mass index (BMI) compared to those with a higher BMI (OR=0.43, 95% CI: 0.21−0.88), those with no unmet health needs (OR=2.00, 95% CI: 1.31−3.06), those with better diet-related circumstances (OR=1.98, 95% CI: 1.15−3.39), those with lower stress (OR=1.77, 95% CI: 1.28−2.44), those with no suicidal ideation (OR=2.92, 95% CI: 1.75−4.87), and those without a history of psychiatric counseling (OR=2.10, 95% CI: 1.02−4.34).
Conclusion: The findings highlight the importance of health behaviors in promoting SRH among older adults in Korea, and emphasize the need for developing and implementing educational programs that reflect these findings.
The Effect of a Virtual Reality-Based Physical Education Program on Physical Fitness among Elementary School Students
Authors: Bae Myeong-Hun
Published: February 2023

Background: This study aimed to verify the effectiveness of a virtual reality-based physical education program on physical fitness among Korean elementary school students.
Methods: The study, conducted at a public school in South Korea in the second semester of 2022, included experimental and control groups of 45 participants each (N=90). All participants underwent physical fitness tests before and after the experiment. The students assigned to the experimental group participated in the virtual reality-based physical education program three times a week for a total of 8 weeks (40 minutes per session), while those assigned to the control group did not participate in any exercise program. The effect size was confirmed using Cohen's d, and a two-way repeated measures analysis of variance was used to analyze changes in physical factors before and after the experiment for each group.
Results: Among the male participants, we observed significant differences in overall health-related physical fitness, cardiorespiratory endurance, muscular strength and endurance, and power between the experimental and control groups (P<0.05). Among the female participants, we observed significant differences in overall health-related physical fitness, cardiorespiratory endurance, flexibility, and muscular strength and endurance between the groups (P<0.05).
Conclusion: Virtual reality-based physical education may help to improve indicators of physical fitness among elementary school students, especially among those who have experienced deterioration of physical fitness during the COVID-19 pandemic. Our results, therefore, highlight the need to establish virtual reality-based physical education facilities at the elementary school level in Korea.
Economic Burden of Multiple Sclerosis Drugs in Iran during 2011-2019
Authors: Asadollahi Mina , Darvishi Ali , Azimi Amirreza , Annabi Majid , Jafariazar Zahra , Heshmat Ramin
Published: February 2023

Background: Due to the invariably progressive nature of multiple sclerosis (MS) and the high economic burden of chronic diseases, this study was performed to estimate the economic burden of MS medications in Iran.
Methods: The present research is a descriptive study performed using comprehensive national data of Iran’s Health Insurance Organization (IHIO). The timeframe for study was 2011-2019. In order to calculate the economic burden of MS medications, the cost of illness (COI) method based on the prevalence approach was used. In this study, economic burden estimation was performed according to available data on medication costs. Data mining was also used to perform different stages of study.
Results: The number of patients receiving MS medications covered by IHIO has increased from 19,367 in 2011 to 50,642 in 2019. The economic burden of MS medications of patients covered by the IHIO increased from $81 million to $96 million between 2011 and 2019, respectively. Among the 9 medications studied, Interferon accounted for a very high share of costs in all years. The cost per patient receiving medication has also increased from $7,000 in 2011 to $18,000 in 2019.
Conclusion: Calculations of the economic burden of MS medications in Iran showed an upward trend during the 9 years of the study, which due to the increasing number of patients in Iran, the arrival of new medications and also the increase in prices.
Comparison of Framingham Cardiovascular Risk Criteria and ASCVD Score in Iranian Obese Patients
Authors: Hasani-Ranjbar Shirin , Razmandeh Rezvan , Ghodssi-Ghassemabadi Robabeh , Khodabakhshi Marjan , Ebrahimpour Mahbube
Published: February 2023

Background: Calculating and predicting the risk of disease plays an important role in preventive medicine. Today, some risk scores have been designed to estimate the risk of cardiovascular diseases (CVDs) by assessing different factors. Obesity is associated with an increased risk of cardiovascular disease, so we decided to calculate the possible risk of heart disease in obese Iranian people to suggest a more accurate calculator.
Methods: In this cross-sectional study, we compared the data of 289 people from Framingham Risk Score and ASCVD Risk Score calculations who had been referred to Shariati Hospital Obesity Clinic, Tehran, Iran from 2016 to 2019. In the form of sub-goals, we examined other factors such as blood pressure and hepatic aminotransferases, etc.
Results: The mean age of participants was 51.20±7.58 years, 86.2% being women. Of the whole, 19.72%, 31.83%, 21.11%, and 27.34% were categorized as overweight, Obese I, II, and III, respectively. According to the ASCVD score 80.3%, 4.8%, and 14.9%, and according to the Framingham score 95.5%, 3.5%, and 1% were classified as low-risk, intermediate-risk, and high-risk. Moreover, a fair agreement was observed between the two-risk score in the whole (Kappa=0.236; P<0.001), overweight (Kappa=0.304; P=0.028), Obese I (Kappa=0.210; P=0.048), Obese II (Kappa=0.268; P=0.015), and obese III (Kappa=0.202; P=0.023).
Conclusion: Despite its age limit, ASCVD has a higher risk of CVDs, causing statin care (which has a protective role for cardiovascular disease) to be given to a larger population.
Differential Expression of lincRNA-ROR Spliced Transcript Variants in Breast Cancer
Authors: Akhtar Mozhgan Saadat , Gholipour Akram , Bagheri Moghaddam Mahrokh , Oveisee Maziar , Mowla Seyed Javad , Malakootian Mahshid
Published: February 2023

Background: We investigated the expression pattern of a human stem cell-specific, large intergenic noncoding RNA (lincRNA) regulator of reprogramming (lincRNA-ROR) and its spliced transcript variants in breast tumors. Breast cancer is the leading cause of cancer mortality in women; therefore, finding a reliable diagnostic tumor marker, based on the molecular profile of tumor cells, is warranted.
Methods: qRT-PCR was used to investigate the expression alteration of a specific stem cell-related lincRNA and its spliced transcript variants in breast tumors which provided by the Iran National Tumor Bank (2014-2016). Suitability of lincRNA-ROR and expression alterations of its spliced transcript variants as breast tumor biomarkers were examined by ROC curve analysis.
Results: Expression was significantly upregulated in lincRNA-ROR variants 1 (NR-048536) and 4 (AB844432) and downregulated in variant 3 (AB844431), with expression levels failing to distinguish between breast tumor types, grades, and malignancy stages. Whereas ROC curve analysis gave good scores to the expressions of variants 1 (AUC=0.7675, P=0.003) and 3 (AUC=0.9383, P=0.00173), suggesting their suitability as potential breast tumor biomarkers, it gave an AUC score of 0.6033 for lincRNA-ROR spliced variant 4 (P=0.4118), denoting its unsuitability as a breast cancer biomarker.
Conclusion: Aberrant expressions of lincRNA-ROR spliced transcript variants could serve as reliable biomarkers with potential usefulness in breast cancer diagnosis. However, further research should elucidate the role and tissue expression of lincRNA-ROR spliced transcript variants in various cancers.
Body Composition Evaluation of Elementary School Students Using Bioelectrical Impedance Analysis in South Korea
Authors: Cho Chaeeun , Jeon Kyoungkyu , Lee Sewon
Published: February 2023

The Article Abstract is not available.
Działalność Polskiego Stronnictwa Ludowego w Stanach Zjednoczonych Ameryki i Kanadzie (występującego pod nazwą Związek Przyjaciół Wsi Polskiej) w okresie prezesury Stanisława Mikołajczyka (1947–1966)
Authors: Turkowski Romuald
Published: February 2023

Artykuł dotyczy działalności Polskiego Stronnictwa Ludowego, które ze względu na przepisy prawa amerykańskiego i kanadyjskiego nie mogło działać pod swoją nazwą. Funkcjonowało tam jako Związek Przyjaciół Wsi Polskiej. Organizacja ta kierowana przez grono polonijnych działaczy ludowych (Stanisław Mermel, Józef Migała, Bolesław Krakowski, Bolesław Biłogan, Tadeusz Paul, Feliks Rembiałkowski), przy wsparciu prezesa PSL Stanisława Mikołajczyka zdołała zorganizować kilkanaście kół PSL/Związku Przyjaciół Wsi Polskiej skupiających kilkuset członków i członkiń. Większość kół PSL/ZPWP działało w Chicago i okolicy. Udało się zorganizować koła PSL na wschodnim wybrzeżu i w kilku stanach środkowych. Koła PSL/ZPWP były oparciem politycznym dla przebywającego na stałe w Ameryce prezesa PSL S. Mikołajczyka. Poprzez swoich członków, którzy zdołali uzyskać dość wysoki status materialny, koła zorganizowały świetlice, domy ludowe oraz zespoły ludowe muzyczne i chóralne, co pozwoliło im zaistnieć w środowisku polonijnym. Koła wspierały linię polityczną S. Mikołajczyka, szczególnie w okresie licznych kryzysów wewnętrznych oraz w czasie ataków przeciwników na to ugrupowanie polityczne, które było spychane na margines emigracyjnej sceny politycznej. Na krótko pojawiło się też koło PSL/ZPWP na terenie Kanady. W artykule opisano działalność tej organizacji w okresie kierowania Naczelnym Komitetem Wykonawczym PSL przez S. Mikołajczyka. Organizacja ta przetrwała na terenie amerykańskim do końca lat 80. XX w. Poprzez zespół amerykański PSL/ZPWP dość wyraźnie oddziaływała na całe emigracyjne Stronnictwo.
Estimation of Phytochemicals and Antioxidant potency of Trigonella foenum-graecum Leaves (Variety HM444)
Authors: Moond Monika , Singh Sushila , Devi Ritu , . Pinki , . Rajita
Published: February 2023

Background: Plants contain phytochemicals that are crucial to their growth and development. The potential health benefits of dietary phytochemicals including flavonoids, isoflavones and other polyphenols. Polyphenolic substances, the largest class of phytochemicals, act as strong antioxidants due to abundance of hydroxyl groups. Trigonella foenum-graceum also known as Fenugreek is rich source of phytochemicals, therefore possess extraordinary healing and medicinal properties. Methods: The present study is designed to evaluate chief phytochemical constituents and antioxidant capacity of acetone extract of dried Trigonella foenum-graecum leaves (Variety HM 444). The phytochemicals like total phenolic content by Folin-Ciocalteu method, total flavonoids by AlCl3 colorimetric assay, total sugars by method of Dubois and reducing sugars by method of Nelson as modified by Somogyi are determined in the acetone extract of leaves. The antioxidant capacity is determined by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and phosphomolybdenum assay. Result: Various phytochemicals such as total phenolic content (3.17 mg GAE/g), total flavonoids (1.34 mg CE/g), total sugars (32.35 mg/g), Reducing sugars (0.53 mg/g) and Non- reducing sugars (31.82 mg/g) are investigated in acetone extract of leaves. The antioxidant activity of leaves extract is evaluated using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and reported an IC50 value of 737.50 μg/mL. The total antioxidant capacity using phosphomolybdenum assay is 28.21 mg AAE/g.
Productivity and Profitability of Green Gram [Vigna radiata (L.) Wilczek] under System of Crop Intensification
Authors: Sowmya K. , Bindhu J.S. , Pillai P. Shalini , Jacob D. , Gladis R.
Published: February 2023

Background: Green gram is one of the important pulse crop and also a drought resistant crop, suitable for summer fallows in Kerala. Though it has multifarious advantages, productivity of green gram is declining year by year due to various reasons. Adoption of low-cost production technologies like system of crop intensification (SCI) practices in green Gram may enhance the productivity and reduce the gap between per capita availability and consumption and enhance the resource use efficiency of the farming system. Methods: A field experiment was laid out in split plot design with four replications during 2022. Main plot treatments were spacings of 25 cm × 15 cm and 25 cm × 25 cm each maintained with single and double seedling per hill. The sub plot treatments include foliar application with urea @ 2%, DAP @ 2%, KNO3 @ 0.5% and DAP @ 2% + KNO3 @ 0.5% at 15 and 30 DAS. Result: The experiment results revealed that spacing of 25 cm × 25 cm or 25 cm × 15 cm with single seedling per hill along with foliar application of KNO3 @ 0.5% or DAP @ 2% + KNO3 @ 0.5% at 15 and 30 DAS recorded higher growth attributes, yield attributes and economics of green gram viz., plant height, number of branches per plant, leaf area, number of pods per plant, seeds per pod, 100 seed weight, net income and benefit cost ratio.
Chickpea Varieties and Time of Sowing Effects on Growth and Yield under North-East Monsoon Influenced in Andhra Pradesh, India
Authors: Sujathamma P. , Nedunchezhiyan M.
Published: February 2023

Background: In Sri Potti Sriramulu Nellore district of Andhra Pradesh, India where North-East monsoon is predominant. During this season, chickpea crop sown during October to November 1st fortnight (FN) causing total crop loss due to high intensity rains in the changing climate scenario. In this context, there is a need for identification of suitable varieties of chickpea with ideal time of sowing for Sri Potti Sriramulu Nellore district under changing climatic situations to enhance the yields of chickpea. Methods: Field experiment was carried out during rabi 2019-20 at Agricultural Research Station, Podalakur (14°22°N latitude, 79°44°E longitude and 43 m above mean sea-level), Sri Potti Sriramulu Nellore district andhra Pradesh to identify the suitable chickpea variety and optimum time of sowing. The field experiment was laid out in Split plot design with 4 varieties of chickpea (V1: Nandyala gram-49, V2: Dheera, V3: Nandyala Senaga-1 and V4: JG-11) as main plot treatments and 3 time of sowings (D1: November 2nd FN, D2: December 1st FN, D3: December 2nd FN) as sub plot treatments in three replications. Result: Nandyala Senaga-1 and Dheera have taken more number days to 50% flowering and maturity. Crop sown on November 2nd FN took significantly more days (42.8) to bear 50% flowering and maturity, while the lowest number of days per 50% flowering and maturity was taken by December 2nd FN sown crop. Chickpea variety Nandyala Gram-49 recorded the highest grain yield (1491 kg ha-1), which was statistically on par with Nandyal Senaga-1 (1465 kg ha-1). The crop sown on November 2nd FN recorded significantly the highest grain yield (1462 kg ha-1), but which was statistically on par with December 1st FN (1424 kg ha-1) sown crop.
LANGUE DES JEUNES: THE USE OF GREETINGS BY E-SPORTS PLAYERS
Authors: Astriani Aveny Septi , Fauzan Lazuardy Akbar , Al-Arief Yusuf
Published: February 2023

One of the media used by teenagers to greet each other is electronic sports. Through e-sports, teenagers wave greetings and express their thoughts in words or sentences. The greeting is closely related to the name and designation used to address people. This qualitative descriptive study discusses e-sports players' greetings, especially those on the E-sport Podcast YouTube channel. The data were collected from five transcribed videos by note-taking. Then, they were analyzed using the theory of greeting according to the theory of Crystal (1997) and Kridalaksana (1980). Finally, the data were presented in tabulation for easy understanding. Based on the data analysis, the greetings used by e-sport players include personal names, pronouns, other nouns, kinship, and other words to show annoyance or anger.
A escola como heterotopia: aceitação e convivência entre bailarinos(as) e não bailarinos(as) em uma escola pública catarinense
Authors: Ambrósio-Accordi Andreia , Accordi Iury de Almeida
Published: February 2023

How to conceive a school as a space of acceptance and coexistence between subjects who act in such different ways? Where do many no longer fit within the pre-established (hetero) norm that judges, sentences and punishes behavior outside of male / female binarism? The idea of a non-heteronormative school fits within the concept of heterotopy, a place or space that operates in non-hegemonic conditions. It is intended to describe situations in which students who have different forms of subjectivity assume a posture of acceptance and conviviality of their differences. A study is proposed using post-structuralist and Queer Theory assumptions, aiming to demonstrate how students (dancers) and non-dancers live in a non-heteronormative way. It was analyzed through ethnography how the students positioned themselves in relation to issues of heteronormative differences and the interactions between dancers and non-dancers students at different times and spaces in the school were described. The analyzed school can be considered a heterotopy, where most students accept each other and live together in order to respect their subjectivities.
Targeting hormone-resistant breast cancer cells with docetaxel: a look inside the resistance
Authors: Scherbakov Alexander M. , Basharina Anna A. , Sorokin Danila V. , Mikhaevich Ekaterina I. , Mizaeva Iman E. , Mikhaylova Alexandra L. , Bogush Tatiana A. , Krasil’nikov Mikhail A.
Published: February 2023

Aim: The study aims to analyze the effect of long-term incubation of ERα-positive MCF7 breast cancer cells with 4-hydroxytamoxifen (HT) on their sensitivity to tubulin polymerization inhibitor docetaxel. Methods: The analysis of cell viability was performed by the MTT method. The expression of signaling proteins was analyzed by immunoblotting and flow cytometry. ERα activity was evaluated by gene reporter assay. To establish hormone-resistant subline MCF7, breast cancer cells were treated with 4-hydroxytamoxifen for 12 months. Results: The developed MCF7/HT subline has lost sensitivity to 4-hydroxytamoxifen, and the resistance index was 2. Increased Akt activity (2.2-fold) and decreased ERα expression (1.5-fold) were revealed in MCF7/HT cells. The activity of the estrogen receptor α was reduced (1.5-fold) in MCF7/HT. Evaluation of class III β-tubulin expression (TUBB3), a marker associated with metastasis, revealed the following trends: higher expression of TUBB3 was detected in triple-negative breast cancer MDA-MB-231 cells compared to hormone-responsive MCF7 cells (P < 0.05). The lowest expression of TUBB3 was found in hormone-resistant MCF7/HT cells (MCF7/HT < MCF7 < MDA-MB-231, approximately 1:2:4). High TUBB3 expression strongly correlated with docetaxel resistance: IC50 value of docetaxel for MDA-MB-231 cells was greater than that for MCF7 cells, whereas resistant MCF7/HT cells were the most sensitive to the drug. The accumulation of cleaved PARP (a 1.6-fold increase) and Bcl-2 downregulation (1.8-fold) were more pronounced in docetaxel-treated resistant cells (P < 0.05). The expression of cyclin D1 decreased (2.8-fold) only in resistant cells after 4 nM docetaxel treatment, while this marker was unchanged in parental MCF7 breast cancer cells. Conclusion: Further development of taxane-based chemotherapy for hormone-resistant cancer looks highly promising, especially for cancers with low TUBB3 expression.
O QUE É MESMO ENCAIXAMENTO EM LINGUÍSTICA SISTÊMICO-FUNCIONAL?
Authors: Scotta Cabral Sara Regin
Published: February 2023

Este artigo objetiva expor como se constitui o encaixamento (HALLIDAY; MATTHIESSEN, 2004; 2014), mecanismo semogênico empregado para definir, delimitar ou especificar termos de uma oração ou mesmo funcionar como Núcleo de um grupo. Denominada oração relativa definidora, a oração encaixada pode funcionar como Pós-Modificador de um grupo nominal ou de um grupo adverbial, ou Núcleo de um grupo nominal. Os exemplos que acompanham esta exposição foram coletados de um corpus com 58 discursos de deputados federais em março de 2020, cujo tema é o Coronavírus no Brasil. Aplicada a ferramenta Voyant.tools, foi constatada a predominância de encaixamento por elaboração.
LÍNGUA INGLESA EM UM SYLLABUS DE FORMAÇÃO DE PROFESSORES PARA O EMI E NO DISCURSO DOCENTE
Authors: Rodrigues Gabriel Salinet , Ribeiro Juliana Michelon
Published: February 2023

Objetivamos identificar como a língua inglesa e o docente são representados em uma entrevista com professor adepto ao Inglês como Meio de Instrução (EMI) e um programa de curso de formação docente para EMI, além de identificar como o programa projeta o docente como leitor-no-texto pela sobreposição de aspectos ideacionais e interpessoais. Os termos de interesse foram identificados manualmente e classificados de acordo com o sistema TRANSITIVIDADE (FUZER; CABRAL, 2010; HALLIDAY; MATTHIESSEN, 2014) da Gramática Sistêmico-Funcional. Observamos que o professor reflete sobre o emprego da língua em sua aula para justificar-se, enquanto o programa trata a língua como ferramenta e não explicita se discute criticamente o uso da língua.
ORAÇÕES COMPLEXAS, UM POTENCIAL DE SIGNIFICADO PARA A CONCRETIZAÇÃO DE VOZES DISCURSIVAS EM EDITORIAIS
Authors: Santos da Silva Hercules
Published: February 2023

O presente artigo, fundamentado na Linguística Sistêmico-Funcional de Halliday (1994), Halliday e Matthiessen (2014) aborda as formas mais ou menos evidentes de que a língua dispõe para veicular vozes, em textos de opinião, por meio de escolhas léxico-gramaticais e semântico-discursiva. O objetivo é investigar o complexo oracional responsável pela veiculação de vozes em editoriais de jornal. Para tanto, a análise, feita manualmente, concentra-se no Sistema de Complexos Oracionais — o componente lógico da metafunção ideacional que abrange os três tipos básico de relações para juntar orações: coesão, interdependência e o encaixamento (HE, 2019). Os resultados revelaram que a maior incidência para o gênero textual argumentativo está no recurso das projeções de locução ou ideia, entretanto, o recurso de expansão ou de encaixamento de orações também possibilita a inserção de vozes externas ao texto.
SIGNIFICADOS EXPERIENCIAIS E INTERPESSOAIS EM UMA CARTILHA DE PORTUGUÊS COMO LÍNGUA DE ACOLHIMENTO
Authors: De Moraes Gugelmim Lorilei , Fuzer Cristiane
Published: February 2023

Este trabalho articula estudos da linguagem na perspectiva sistêmico-funcional ao contexto de Português como Língua de Acolhimento. O objetivo é evidenciar, por meio da análise de realizações léxico-gramaticais de transitividade, funções de fala e modalidade significados que constroem o campo e as relações em um material didático de Português como Língua de Acolhimento. Alicerçado na perspectiva sistêmico-funcional da linguagem (HALLIDAY, 1989; HALLIDAY; MATHIESSEN, 2014), os resultados evidenciaram que as informações estão concentradas em dois campos documentação e legislação. Quanto à variável relações, verificou-se a prevalência de declarações e perguntas e o uso de modalidade para amenizar comandos.
INTERAÇÃO EM BLOGS DE PROFESSORES DE INGLÊS
Authors: Sartin Fabiola , Vian Junior Orlando
Published: February 2023

Considerando a interação em diferentes contextos online, este artigo objetiva discutir a Afiliação estabelecida em comentários publicados em blogs de professores de inglês e sua relação com o sistema de Avaliatividade. A teoria da Afiliação (Knight 2010) aborda a língua como um processo social capaz de negociar valores compartilhados em um texto e o sistema de Avaliatividade (Martin e White 2005; White 2004) explora, descreve e explica a forma pela qual a língua é utilizada para avaliar. Os resultados demonstram que processos sociais no discurso de professores de inglês são responsáveis pela interação crítica e são capazes de compartilhar valores no âmbito de uma comunidade.
UMA PROPOSTA SOCIOSSEMIÓTICA PARA A ANÁLISE VISUAL DE JOGOS BIDIMENSIONAIS
Authors: Matumoto André de Oliveira , Gonçalves-Segundo Paulo Roberto
Published: February 2023

Atualmente, os videogames constituem-se como objeto de crescente relevância no meio acadêmico. Assim, faz-se necessária uma metodologia acerca das construções de sentido nesses textos. Neste artigo, propõem-se categorias de análise visual e discursiva de jogos bidimensionais por meio do quadro teórico da Semiótica Social. Partindo da natureza multimodal e interativa dos videogames, analisa-se como a modalidade visual em si e em suas interfaces constrói significados por meio de estratégias ludossemióticas. Para tal, explorar-se-á o estágio amazônico no jogo Ducktales (CAPCOM, 1989), de modo a descrever como as escolhas semióticas empregadas constroem significados e discursos a respeito do espaço representado.
SIGNIFICADOS SOCIOSSEMIÓTICOS DE ANÚNCIOS PUBLICITÁRIOS
Authors: SARINHO JÚNIOR José Maria de Aguiar , ARAÚJO Alex Marcelo da Silva , BARBOSA Maria do Rosário da Silva Albuquerque
Published: February 2023

A presente pesquisa tem como objetivo analisar, em perspectiva multimodal, anúncios publicitários no intuito de compreender as contribuições da Gramática do Design Visual para a construção de saberes multimodais e para a formação do leitor e do escritor crítico-reflexivo na escola. Para isso, este trabalho apresenta-se em caráter qualitativo e exploratório e de natureza básica, sendo o corpus formado por seis anúncios publicitários de marcas famosas em contexto de circulação nacional, destacando imagens multimodais digitais que veiculam na web, e traz como arcabouço teórico, principalmente, as postulações de Halliday e Matthiessen (2004) e Kress e van Leeuwen (2000, 2006[1996]).
ANÁLISE DAS VARIÁVEIS DO CONTEXTO DE SITUAÇÃO PARA EXPOSIÇÃO DE UM PONTO DE VISTA EM ARTIGOS DE OPINIÃO
Authors: Damascena Adonelson Nascimento , Fonseca Vilma Nunes da Silva
Published: February 2023

Este artigo apresenta um estudo que teve como objetivo descrever e analisar como a desconstrução e a leitura detalhada, duas fases do programa Ler para Aprender (ROSE; MARTIN, 2012), propiciaram a análise das variáveis do contexto de situação e de que forma colaborou para a exposição de pontos de vista em artigos de opinião produzidos por uma turma da 2° série do Ensino Médio. A investigação em questão foi conduzida à luz dos princípios da pesquisa-ação, ocorrida no contexto do Programa de Residência Pedagógica / Núcleo de Língua Portuguesa, e está ancorada no arcabouço teórico-metodológico da Linguística Sistêmico-Funcional de Halliday, concentrando o interesse mais especificamente na Pedagogia de gêneros da Escola de Sydney. Para o desenvolvimento da pesquisa foram analisadas as produções textuais dos alunos (dois exemplares de um universo de dezoito textos) e as respostas a uma atividade de interpretação elaborada com vistas à exploração das variáveis do contexto de situação. A análise evidenciou que as etapas de desconstrução e de leitura detalhada propiciaram a compreensão das variáveis contextuais (campo, relação e modo). Tal compreensão foi determinante para que a produção textual ocorresse na fase de escrita autônoma, vindo a impactar diretamente nas escolhas léxico-gramaticais e semântico-discursivas dos alunos nos textos analisados.
O O GÊNERO EDITORIAL E SUA PROGRESSÃO
Authors: De Vasconcelos Picanço Isadora
Published: February 2023

No gênero editorial, as conjunções podem desempenhar papel essencial para a argumentação. No entanto, em sua organização, há outras estratégias coesivas que cumprem, igualmente, a função de encadear os enunciados e dar orientação ao sentido do texto. Considerando-o como unidade básica da manifestação da linguagem, este trabalho investiga como se dá a progressão temática em tal gênero jornalístico. Para isso, apoia-se nos fundamentos da Gramática Sistêmico Funcional (HALLIDAY, 1994) para identificar o papel da estrutura temática no processo coesivo. Assim, pretende-se não só colaborar nos avanços da Linguística Sistêmico-Funcional, mas também no desenvolvimento do ensino de língua portuguesa.
REPRESENTAÇÕES LINGUÍSTICAS DE MULHERES TRANS SOBRE A TRANSEXUALIDADE NO CONTEXTO CEARENSE
Authors: Silva Júnior Antonio Soares da
Published: February 2023

O objetivo deste artigo é analisar a representação linguística de mulheres transexuais cearenses sobre a transexualidade feminina. Para gerar e coletar dados, utilizei a etnografia online (ANDROUTSOPOULOS, 2008) através de entrevistas semiestruturadas. Na análise, as escolhas léxico-gramaticais foram consideradas à luz do sistema de transitividade da Linguística Sistêmico-Funcional (HALLIDAY; MATTHIESSEN, 2014) e da categoria de Inclusão da Teoria de Representação de Atores Sociais (VAN LEEUWEN, 2008). A análise indica que a experiência transexual das participantes está relacionada, principalmente ao mundo mental do ‘sentir’ e que as participantes utilizaram assimilações e classificações para se autorrepresentarem como participantes ativas em diversas situações.
Product Review Analysis with Filtering Vulgarity & Ranking System Based on Transaction & Otp
Authors:   M.E Computer Science & Engineering Rmd Engineering College, Ms Archana U , Banu M.Sheerin ,   M.E Computer Science & EngineeringRmd Engineering College
Published: February 2023

Product recommendation is a business activity that is critical in attracting customers.Accordingly, improving the quality of a recommendation to fulfill customers needs is important in fiercely competitive environments.Collaborative filtering (CF) technique has been proved to be one of the most successful techniques in recommender systems.Two types of algorithms for collaborative filtering have been researched memory-based CF and model-based CF.