bluuebunny/crossref_metadata_2025 huggingface dataset:
Air, Skin, and Biological Monitoring of French Fire Instructors’ Exposure to Particles/PAHs During Controlled Fire and Mitigation Strategies
Authors: Zangl Pauline , Collart Clément , Persoons Renaud
Published: January 2025

Occupational exposure as a firefighter was recently classified as carcinogenic to humans by the IARC. Fire instructors’ exposure to carcinogenic PAHs is a major concern, and studies that have tried to assess the determinants of their exposure are scarce. An air and biomonitoring study was conducted in fire instructors performing simulated training exercises in enclosed containers. Air samples were collected, as well as urine samples from 22 firefighting instructors, and skin wipes were collected from FFs’ skin at the end of the exercises. PAH metabolites (1-hydroxypyrene, 3-hydroxybenzo(a)pyrene, 2/3-hydroxyfluorene, and 2/3-hydroxyphenanthrene) were measured in urine samples at three sampling times (beginning of shift, end of shift, and next morning). Airborne PAHs were dominated by low molecular weight compounds (naphthalene), and levels were as high as 67 µg·m−3 close to the containers, decreasing at higher distances. Skin contamination was observed both on the neck/face and hands/wrists of fire instructors and pilots. Ten times lower skin contamination was observed when nitrile undergloves were worn. High internal exposure was measured, with 1-hydroxypyrene and 3-hydroxybenzo(a)pyrene levels frequently exceeding maximum recommended values in occupational settings (up to 2.8 µmol/mol creatinine for 1-OHP, 14 µmol/mol creatinine for ΣOH-PAH, and 1.0 nmol/mol creatinine for 3-OHBaP), whereas benzene exposure was revealed to be very low. These types of exposure were found to derive both from dermal absorption (combustion products deposited on the skin) and inhalation (when removing SCBA outside the containers). Several recommendations are proposed in order to reduce both exposure routes (nitrile undergloves and half-masks in the vicinity of containers), harmonise decontamination (PPEs) and cleaning procedures, and prevent the dermal absorption of PAH from turnout gear. This study emphasises the complex PAH exposure profiles of fire instructors and characterises the main drivers of exposure, highlighting the need for better mitigation strategies.
Contamination Characterization, Toxicological Properties, and Health Risk Assessment of Bisphenols in Multiple Media: Current Research Status and Future Perspectives
Authors: Long Fangyun , Ren Yanqin , Bi Fang , Wu Zhenhai , Zhang Haijie , Li Junling , Gao Rui , Liu Zhengyang , Li Hong
Published: January 2025

Bisphenols (BPs) are ubiquitous environmental endocrine disruptors that cause various human health hazards and pollute water, soil, and the atmosphere to varying degrees. Although various studies have investigated the pollution characteristics and health hazards of BPs in different media, a systematic review of BPs in the broader environmental context is still lacking. This study highlights the pollution characteristics, detection methods, and risk assessment status of BPs by combining relevant studies from both domestic and international sources, and their environmental distribution characteristics are summarized. The results show that BP pollution is a widespread and complex global phenomenon. Bisphenol A (BPA) remains the predominant component of BPs, which can damage the nervous and reproductive systems. At present, high-performance liquid chromatography–tandem mass spectrometry, high-performance liquid chromatography, and liquid chromatography–tandem mass spectrometry are the main detection methods used for BPs. BPs can also damage the reproductive system, leading to germ cell apoptosis and ovarian damage. Future research should focus on expanding the BP testing repertoire, advancing rapid detection techniques, elucidating toxic mechanisms, conducting comprehensive safety assessments, and developing systematic health risk assessment methods. These efforts will provide a scientific foundation for preventing and controlling emerging pollutants.
Next Generation Risk Assessment to Address Disease-Related Vulnerability—A Proof of Concept for the Sunscreen Octocrylene
Authors: Fernández-Martín María-Elena , Tarazona Jose V.
Published: January 2025

Risk assessment for cosmetics in the European Union (EU) are triggered by a ban on animal testing and concerns of endocrine disruption (ED). The risk assessment focuses on healthy populations and, for potential ED, includes specific developmental stages as vulnerable due to specific concerns on endocrine effects. However, the assessment focuses on healthy individuals and does not consider that some pathologies may increase dermal absorption and even vulnerability to endocrine disruptors. Data from the EU risk assessment, human pharmacokinetic studies and ToxCast bioactivity were combined in a hypothesis-driven Next-Generation Risk Assessment to identify possible risk drivers for vulnerable populations including oncological patients and atopic dermatitis. In vitro effects are observed at concentration in the order of measured plasmatic levels under normal use patterns. The induction of hepatic enzymes is the most relevant bioactivity endpoint, in line with animal findings. The information on endocrine potential is inconclusive, and the possibility for skin effects and endocrine mechanism linked to tumor induction require further elucidation. The information on octocrylene (CAS number: 6197-30-4) bioactivity is limited, lacking information on the metabolites and the immunotoxicity potential, particularly relevant for oncological patients.
An Evaluation of Secondary Mineral Formation/Dissolution and Phase Separation Based on Mg Isotopic Fractionation: The Shallow-Water Hydrothermal System in Milos, Greece
Authors: Chen Yi-Chi , You Chen-Feng , Chung Chuan-Hsiung , Huang Kuo-Fang , Wu Shein-Fu , Valsami-Jones Eugenia , Baltatzis Emmanuel
Published: January 2025

This study investigates Mg isotopes (δ26Mg) in vent fluids from Milos, Aegean Sea, to evaluate phase separation and secondary mineral formation. The δ26Mg vary significantly in Milos, exceeding 0.66‰, allowing for the classification of the fluids into three sub-groups based on chemical characteristics: seawater-like, cave fluids, and submarine-brines. The seawater-like fluids exhibit large δ26Mg variation, −0.64 to −1.18‰, and mostly follow a Rayleigh fractionation trend, with a fractionation factor α = 1.00020 ± 0.00011. The cave fluids are highly acidic, have low Cl, are vapor-rich, and display heavy δ26Mg compositions (−0.52 to −0.63‰). The submarine-brines are characterized by high Cl, high non-volatile metals, and light δ26Mg (−0.65 to −1.00‰). The latter two fluid types represent vapors and brines, respectively, which underwent phase separation at depth in Milos. These δ26Mg values were combined with major/trace elements, as well as Li and B isotopes, to explore possible controlling mechanisms. We report for the first time a shallow submarine hydrothermal system that has a vapor component enriched in heavy δ26Mg, but with no detectable isotopic changes in the brines. It is evident that δ26Mg in vent fluids is unique for separating effects of water/rock interaction and secondary mineral and phase separation at shallow-water systems.
Montreal Cognitive Assessment (MoCA) use in general practice for the early detection of cognitive impairment: a feasibility study
Authors: Carton Cassandre , Calafiore Matthieu , Cauet Charles , Messaadi Nassir , Bayen Marc , Wyts David , Messaadi Wassil , Richebe Teddy , Bayen Sabine
Published: January 2025

Background

GPs can detect cognitive impairment (CI) at a very early stage, allowing early support for people and their caregivers. The early onset of CI is between 50 years and 60 years. Currently, in France, the Mini-Mental State Examination (MMSE) remains the most used screening test, although it has a lower sensitivity and specificity than the Montreal Cognitive Assessment (MoCA) for detecting mild CI, taking an average of 15 minutes to complete.

Aim

To investigate the feasibility of the MoCA during routine consultations in general practice for the early detection of CI and to determine prevalence of CI in a primary care setting.

Design & setting

A quantitative, prospective feasibility study was carried out in real-life working conditions during routine GP consultations in France.

Method

GPs performed MoCA on adults aged ≥50 years, without suspected or confirmed CI.

Results

Sixty-one GPs performed 221 MoCA with a mean duration of 8 minutes and detected mild neurocognitive impairment in 62% of patients.

Conclusion

The MoCA is feasible and easy to perform during routine consultations in general practice by trained and experienced physicians.
Characteristics of women on opioid substitution therapy in primary healthcare in Tshwane (South Africa): a retrospective observational study
Authors: Goeieman Daniela S , Mash Robert , Gloeck Natasha R , Scheibe Andrew
Published: January 2025

Background

Women who use drugs face specific challenges compared with men such as higher rates of HIV infection, unsafe injecting practices, and intimate partner violence (IPV). However, this population’s access to drug dependence treatment and gender-sensitive interventions remains limited, leading to unmet needs and increased vulnerability.

Aim

To investigate the characteristics of and associations with retention in care among women on opioid substitution therapy (OST) in a community-based primary care setting.

Design & setting

A descriptive observational study within the Community Orientated Substance Use Programme in Tshwane, South Africa.

Method

Data from 199 women (aged>18 years) on OST was extracted from an electronic database and paper-based files. Data were analysed descriptively, and inferential analysis looked for association of variables with retention on OST for ≥6 months.

Results

The majority of participants were unemployed, with 44.3% aged 20–29 years. During the initiation and course of OST, 39.2% of women had an intimate partner of which 37.2% reported IPV, and 19.2% were pregnant. Retention on OST was significantly associated with increasing age at initiation (P= 0.047), knowledge of HIV status (P= 0.029), an increase in the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) score (P= 0.023), and methadone dose (P<0.001). Factors such as race, employment status, health-system level, pregnancy, intimate partner using substances, IPV, route of administering opioids, and having tuberculosis and/or hepatitis C exposure did not show a significant relationship with retention on OST (P>0.05).

Conclusion

This study reveals specific vulnerabilities in women receiving OST, emphasising the need for the integration of interventions to address reproductive health, violence mitigation, infectious disease, and polydrug use into care.
Research on toponymic nicknames of the states in the USA
Authors:   Ufa University of Science and Technology, Russia, Urazmetova Aleksandra Vladimirovna
Published: January 2025

This article explores the characteristics of secondary nominations based on the toponymic nicknames of the states in the USA. The extensive use of toponymic nicknames is a defining aspect of the entire toponymic system in the USA. This study gathered 428 nicknames of the states through a continuous sampling method from contemporary lexicographic, linguistic, toponymic, explanatory dictionaries, guidebooks, and online sources. The linguistic material obtained has been thoroughly examined in the article from various perspectives, including structural, semantic, linguacultural, and connotative analyses. Furthermore, an analysis of the cognitive mechanisms involved in the formation of toponymic nicknames has been conducted. This comprehensive study allows us to uncover the ethnocultural identity of the American linguistic persona, illuminate the connection between nomination and the culture or self-awareness of the people, identify the mechanisms involved in the formation of toponymic vocabulary, and evaluate the creative potential of human thought in utilizing toponymic vocabulary. Through this research, we can identify the most productive structural models, cognitive mechanisms, semantic, functional, and evaluative characteristics of a toponymic nickname. The conclusions drawn from this study are supported by the results of quantitative analysis.
The concept of the international database of onomastic terminology (ONOMTERM)
Authors:   Ľudovít Štúr Institute of Linguistics, Slovak Academy of Sciences, Slovakia, Valentová Iveta , Harvalík Milan ,   Ľudovít Štúr Institute of Linguistics, Slovak Academy of Sciences, Slovakia, Gałkowski Artur ,   University of Łódź, Poland
Published: January 2025

This article presents the concept of a multilingual onomastic terminology database, which will contain an inventory of terms in various languages and onomastic schools. The definitions of terms and their synonyms, variants and related terms are given in the sense in which they are understood and used in particular languages and onomastics schools. The database should primarily serve as a relevant source for the updating, unification, harmonization and codification of onomastic terminology at the international level (within the ICOS Terminology Group) and as a model for other similar databases. It should also be a tool for translators, onomasticians, linguists and specialists in fields for which onomastics is an auxiliary discipline.
When Onomastics faces the Law: A Review of I.M. Nick (ed.), Names, naming, and the Law: Onomastics, identity, power, and policy, New York: Routledge, 2023, 266 pp., ISBN 978-1-032-55642-0
Authors:   Professor Emeritus, Doshisha University, Kyoto, Japan, Loveday Leo
Published: January 2025

This review examines I.M. Nick’s groundbreaking edited volume Names, naming, and the Law: Onomastics, identity, power, and policy (Routledge, 2023), which represents the first comprehensive attempt to bridge onomastics, bureaucratic policymaking, and jurisprudence. Through thirteen thematically distinct chapters, eleven leading experts explore how topics in anthroponymy, toponymy, chrematonymy, taxonomy, nosonomy, and ethnonymy are shaped by legal frameworks and official policies. Although primarily oriented toward a U.S. context and drawing mainly from secondary sources rather than original empirical research, the book successfully illuminates the complex interplay between naming practices and legal systems, particularly in areas such as personal naming rights, geographical designations, biological nomenclature, and trademark law. Despite these constraints, the volume navigates hitherto rarely explored territory, thereby laying seminal foundations for what promises to be a rich field of inquiry at the intersection of onomastics and the law.
Attribuer des prénoms à Santiago de Cuba et à Tlalnepantla de Baz, au Mexique, en 1970 : convergences et divergences dans deux variantes de l’espagnol
Authors:   Universidad Nacional Autónoma de México, López Franco Yolanda Guillermina , Rosales Novoa Sonia ,   Academia de Ciencias et Centro de Superación Cultural de Santiago de Cuba
Published: January 2025

This contribution has for an antecedent a comparative socioanthroponymic study of the year 1960, as well as works on the Mexican, French, and Cuban prenomination of the twentieth century. It is both quantitative and qualitative, and analyzes a corpus of birth certificates from the 1970 civil registry, at Tlalnepantla de Baz and Santiago de Cuba. It is based on classical texts in French onomastics, pragmasemantic theories of proper name and anthroponym, and socioanthroponymy. Each name is compared with the date of birth of the bearer, the list of Catholic saints, and the names of his/her ascendants. Attribution models are also compared in both cities. Main trends: a) permanence of the traditional model in Tlalnepantla, and b) significant presence of neologisms in Santiago de Cuba. This is the result of socioanthroponymic factors operating in 1970, especially the impact of social movements and the Cuban revolution. The richness of denominational practices, convergent and divergent, highlights the importance of studying the Cuban and Mexican variants of Spanish from a socionomastic perspective.
Crowdsourcing and digitization as a tool for creating sustainable development - a case study of public administration
Authors: Kuzionko-Ochrymiuk Ewa , Grześ Anna , Szanter Renata , Dyl Krzysztof , Henhappel Sylwia , Klimek Julia Anna , Zioło Magdalena , Niedzielski Piotr , Klimek Jordan
Published: January 2025

Goal: Building stable infrastructure and promoting innovation is the ninth goal of sustainable development. It is implemented, among others, by increasing access to information and communication technologies and providing affordable and universal access to the Internet. The aim of the article is to assess the current level of access to broadband Internet and the possibility of its faster dissemination using a crowdsourcing platform, a new solution used by public administration in Poland. The platform involves the public and shows public administration's experience in using it to ensure wide public access to broadband Internet, which translates into the implementation of sustainable development goals thanks to the digitisation of socio-economic processes. Research method: The study used a comparative analysis of indicators in the area of information and communication technologies collected by the Central Statistical Office and a case study of the use of a crowdsourcing (internet) platform called SIDUSIS (Information System on Access to Fixed Broadband Internet Services) to optimise the implementation of investments in the development of broadband Internet in Poland. The analysis of the implementation effects and the indication of the impact of digitalisation on sustainable development goals allowed us to indicate the validity of using the concept of crowdsourcing and crowdsourcing platforms not only in the activities of enterprises but also in the activities of public administration in Poland. Conclusions: The analysis of literature and quantitative data allowed us to indicate that the development of access to broadband Internet is one of the factors accelerating the implementation of sustainable development goals and to indicate the effective use of the idea of crowdsourcing to modernise infrastructure. Originality/value/implications/recommendations: So far, the idea of crowdsourcing, as well as crowdsourcing platforms, has been used mainly in the enterprise sector and in public administration to promote the idea of citizen budgets. The experience gained has shown that it is justified to involve society in increasing the availability of broadband Internet. This does not require large investment outlays and allows decision-makers to quickly identify problems with this accessibility and optimise work in this area.
Оценка исходного материала для селекции могара (Setaria Italica ssp. moharicum) по урожайности и биохимическому составу биомассы и семян
Authors: Родина Т.В. , Асташов А.Н. , Киреева О.В. , Подгорнов Е.В.
Published: January 2025

Актуальность проводимых исследований обусловлена изменениями климатических условий, что приводит к частому проявлению неблагоприятных факторов и, как следствие, снижению продуктивности сельскохозяйственных растений. Научные исследования направлены на разработку новых сортов культурных растений, обладающих высокой устойчивостью к стрессовым условиям. Успешные исследования в этой области могут привести к созданию устойчивых сортов, способных не только обеспечивать животноводческие комплексы кормами, но и повышать экологическую устойчивость отрасли как селекции, так и кормопроизводства. Для условий аридного климата могар является перспективной культурой. В статье представлены данные по изучению коллекционного питомника могара. За период с 2021 по 2023 гг. было изучено 36 образцов различного происхождения. Посев проводили в оптимальные для культуры сроки – в третьей декаде мая. В качестве стандарта использовали районированный сорт – Аскет. Комплексное изучение исходного материала позволило выделить сортообразцы на высокую урожайность: надземной биомассы (> 18,00 т/га) – к-605, к-993, к-1027, к-1628, к-1726, Атлант; зерна (˃ 1,90) – к-37, к-80, к-1356. Высокое содержание сырого протеина: в сухой биомассе (> 0,70 т/га) установлено у образцов к-605, к-993, к-1027, к-1775, Атлант; в зерне (˃ 1,20 т/га) установлено у образцов могара к-37, к-80, к-1356, к-1748.

The relevance of the research is due to changes in climatic conditions, which leads to the frequent manifestation of adverse factors and, as a result, a decrease in the productivity of agricultural plants. Scientific research is aimed at developing new varieties of cultivated plants that are highly resistant to stressful conditions. Successful research in this area can lead to the creation of resistant varieties capable not only of providing livestock complexes with feed, but also of increasing the environmental sustainability of the industry of both breeding and feed production. Mogar is a promising crop for arid climate conditions. The article presents data on the study of the Mogar collection nursery. During the period from 2021 to 2023, 36 samples of various origins were studied. Sowing was carried out at the optimal time for the culture – in the third decade of May. The zoned Ascet variety was used as a standard. A comprehensive study of the source material allowed us to identify varietal types: for high yields: aboveground biomass (> 18.00 t/ha) – k-605, k-993, k-1027, k-1628, k-1726, Atlant; grains (1.90) – k-37, k-80, k-1356. High crude protein content: in dry biomass (> 0.70 t/ha) was found in samples k-605, k-993, k-1027, k-1775, Atlant; in grain (1.20 t/ha) it was found in samples mogar k-37, k-80, k-1356, k-1748.
Selection of reference genes for gene expression analysis by RT-qPCR in Robinia pseudoacacia L. under drought conditions
Authors: Tretyakova A.V. , Zybinskaya P.A. , Krylov P.A.
Published: January 2025

obinia pseudoacacia L., or black locust, is a valuable tree species known for its rapid growth in drought conditions. Due to its adaptation to diverse climates, R. pseudoacacia is widely used in agroforestry to combat soil erosion, restore land, strengthen sand, and increase pasture productivity. However, to effectively utilize R. pseudoacacia in drought conditions, it is essential to understand the molecular mechanisms underlying its adaptation to this stressor. One of the key tools for investigating these mechanisms is reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). To achieve accurate results, it is crucial to select appropriate reference genes to normalize the expression data of genes involved in stress response. The aim of this study is to identify the most suitable reference genes for quantitative gene expression analysis in R. pseudoacacia using RT-qPCR. An analysis was performed via RT-qPCR to evaluate the stability of expression of several housekeeping genes under simulated soil drought in laboratory conditions. Based on gene expression stability data analyzed with RefFinder, one gene was identified as the most stable under drought conditions. Results from various algorithms indicated that ACT_v2 is the most stable reference gene for R. pseudoacacia under drought conditions, while ACT_v1showed the least stability

Робиния псевдоакация (Robinia pseudoacacia L.) – ценная древесная порода, быстро растущая в засушливых условиях. Благодаря адаптации к различным климатическим условиям она широко используется в агролесомелиорации для борьбы с эрозией почв, восстановления земель, укрепления песков и повышения пастбищной продуктивности. Однако, для эффективного использования R. pseudoacacia в условиях засухи необходимо понимать молекулярные механизмы ее адаптации к данному стрессовому фактору. Одним из ключевых инструментов для исследования этих механизмов является метод полимеразной цепной реакции в реальном времени с обратной транскрипцией (ОТ-ПЦР-РВ). Для достижения высокоточных результатов важно подобрать референсные гены, которые необходимы для нормализации данных экспрессии генов, ответственных за стрессовые реакции. Цель данной работы – отобрать наиболее подходящие референсные гены для количественного анализа экспрессии генов R. Pseudoacacia с помощью ПЦР в реальном времени. С помощью метода ОТ-ПЦР-РВ проведено исследование стабильности экспрессии нескольких генов домашнего хозяйства в условиях моделирования почвенной засухи в лабораторных условиях. На основе данных об экспрессии изучаемых генов с помощью инструмента RefFinder был выбран один наиболее стабильный в условиях засухи ген. Результаты, полученные различными алгоритмами, показали, что ACT_v2является наиболее стабильным референсным геном R. pseudoacacia в условиях засухи, в то время как ACT_v1 продемонстрировал наименьшую стабильность.
Percepción de la elaboración de tesis y la tutoría de investigación: experiencias en el posgrado
Authors: Ríos Mena Gaxiola Javier Arturo , Zazueta Beltrán Diana Korinna , Cruz Morales Karla Noelia
Published: January 2025

Este trabajo tiene la finalidad de explorar la percepción de los estudiantes matriculados y egresados no titulados sobre la elaboración de tesis y la tutoría de investigación a partir de sus experiencias en el posgrado de la Universidad Autónoma de Occidente (UAdeO). Se realizó un estudio cualitativo bajo un análisis de contenido desde la perspectiva fenomenológica de tipo empírica, la muestra estuvo conformada por 17 participantes con el criterio de selección no probabilístico por conveniencia. El grupo de enfoque fue la técnica de apoyo para recoger los datos. En los hallazgos se identificaron aspectos multifactoriales que inciden en el proceso de elaboración de tesis, así como la necesidad de promover la formación continua del tutor. Se concluye que es imperativo que las Instituciones de Educación Superior trabajen en la elaboración de modelos tutoriales en posgrado con un sentido integral-humanista.
Percepción de la violencia verbal en estudiantes de educación secundaria
Authors: Reyes Jaimes Gabriel Renato , Velázquez Reyes Luz María
Published: January 2025

Se presentan los resultados sobre la percepción de la violencia verbal entre el estudiantado de 28 escuelas secundarias del Estado de México. Con el objetivo de examinar, desde el punto de vista del alumnado, la percepción de la violencia verbal en las interacciones institucionales entre pares y en la relación maestro-alumno, así como los hábitos lingüísticos en la utilización de disfemismos para las prácticas comunicativas. El estudio se basó en un enfoque cualitativo, con un paradigma interpretativo y se integró con dos contextos: 1) la percepción de la violencia verbal en estudiantes y 2) los hábitos lingüísticos de los alumnos de educación secundaria, identificando en ambos casos el uso reiterado de disfemismos. La muestra del estudio estuvo compuesta por 7,068 estudiantes de un universo de 12,472 inscritos en las 28 escuelas participantes; se les aplicó un autoinforme mediante la plataforma Google Forms. El reporte final indica que, en el alumnado de secundaria, el uso de disfemismos se bifurca en dos vías: una, remite a la conformación de una gramática de la agresividad y deviene en violencia verbal, y otra representa una forma de construir la identidad y generar lazos afectivos con sus iguales, perfilando una gramática del reconocimiento.
Realidad aumentada para la mejora de la experiencia del turismo cultural
Authors: Ibarra Vázquez Arnoldo , Soto Karass José Guadalupe , Ibarra Michel Juan Pedro
Published: January 2025

La innovación digital avanza exponencialmente, se desarrollan y adaptan nuevas tecnologías a diferentes sectores industriales, como el médico, educativo, deportivo, de videojuegos y turístico. Este es el caso de la Realidad Aumentada (RA), una tecnología basada en la interacción entre el mundo digital y el mundo real, donde las personas pueden percibir más de lo que el mundo real proporciona. La RA ofrece al turismo una nueva oportunidad de interacción con destinos, conocimiento cultural, infraestructura arqueológica y pasatiempos, proporcionando todo ello con solo un dedo a través de los teléfonos inteligentes. Esta investigación tiene como objetivo evaluar la viabilidad de la implementación de la RA en áreas turísticas culturales, por lo que parte de su análisis se enfoca en el uso de la RA en sitios patrimoniales y arqueológicos con el fin de conceptualizar tendencias en el turismo cultural mediante aplicaciones móviles. Se realizó un análisis descriptivo y comparativo de la literatura para comprender las posibilidades de la RA y su importancia en el turismo cultural obteniendo información destacable, aplicable y deseable en diversas áreas turísticas. Se propone la utilización de la RA en áreas arqueológicas, museos y culturales como Pueblos Mágicos en México para impulsar la digitalización turística, así como la creación de rutas y actividades personalizadas en conjunto con la Inteligencia Artificial (IA) para el desarrollo del turismo cultural.
El impacto de la política del ajuste salarial. Conformación de nuevas segmentaciones laborales en Chiapas, México, 2005-2021
Authors: Pintor Sandoval Renato
Published: January 2025

Desde los años ochenta, las reformas estructurales establecidas en México en materia de empleo contribuyeron a la composición de una mayor segmentación laboral, concentrado en épocas recientes en grandes componentes de la economía informal. Para el estado de Chiapas, el crecimiento de esta actividad obedece a las políticas de ajuste económico, incentivado por las rachas del desempleo abierto y bajos salarios como medida regulatoria antiinflacionaria. El objetivo de esta investigación analiza la conformación del nuevo mercado laboral en esta región. Bajo el enfoque de la Teoría de la Segmentación del Mercado de Trabajo (TSMT) y la información, interpretación y análisis recabado por la Encuesta Nacional de Ocupación y Empleo (ENOE) del Instituto Nacional de Estadística y Geografía (INEGI) durante el periodo de 2005 al 2021, permiten visualizar los siguientes resultados: 1) Mayor polarización socioeconómica y dependiente de los programas sociales. 2) Extensión la vida laboral, incrementado los empleos secundarios con la problemática de las garantías laborales y el régimen pensionario. 3) Incorporación de nuevos grupos poblacionales en actividades flexibles con sistemas de bienestar reducidos.
Red comunal vecinal, fomento de una cultura de paz
Authors: González Rodríguez Carmen María , Romero Castro María del Rosario
Published: January 2025

El autocuidado en la sociedad es de vital importancia para la prevención del delito, los grupos sociales contribuyen en su comunidad si son encauzados en el bienestar común y con el apoyo y colaboración de todos o la mayoría de los integrantes, es de suma importancia que las autoridades acrecienten la participación ciudadana en la práctica de sus políticas y acciones públicas para lograr frutos de impacto social que contribuyan en la ayuda, la mejora y calidad de vida vecinal, principalmente en el cuidado de espacios públicos que fomenten una cultura de paz. El gobierno debe impulsar el liderazgo colonial y de autoorganización entre vecinos para cuidarse y promover el desarrollo del contexto donde habitan. Se aplicó una entrevista a una muestra de 23 vecinos de un fraccionamiento del H. Ayuntamiento de Ahome, Sinaloa, México, los datos se analizaron de manera cualitativa. El objetivo de este estudio es conocer si en una red comunal vecinal perciben el cuidado y apoyo entre vecinos como el fomento de una cultura de paz, los resultados muestran que a todos los integrantes les brinda paz, seguridad y confianza y les ha beneficiado en el sentido de apoyo y pertenencia al estar integrado en el grupo de vecinos, asimismo, consideran que se comparte información útil, con un fin común en materia de alerta de delincuencia.
Costos de operación y la rentabilidad en restaurantes de comida típica mexicana
Authors: Quintero-Ramírez Juan Manuel , Ricardo-Jiménez Stephanie , Salazar-Echeagaray Teresa Irina , Olguín-Martínez Cynthia Michel
Published: January 2025

Los costos que genera el trabajo de un restaurante poseen un efecto directo en la rentabilidad económica. El objetivo de la investigación consiste en evaluar la incidencia que poseen los costos de operación en la rentabilidad de restaurantes de comida típica mexicana, dada la tendencia al crecimiento de este tipo de negocio, la preferencia que han adquirido en los clientes, así como los niveles de satisfacción. La investigación posee un enfoque mixto de tipo no experimental y de alcance descriptivo. El cuestionario aplicado consideró 9 variables, evaluadas mediante la escala de Likert aplicado a 160 restaurantes escogidos de manera aleatoria. Los métodos empleados permitieron realizar un análisis del comportamiento de cada variable en función de la rentabilidad de la organización evidenciando la relación existen entre los costos de servicio u operación con la rentabilidad en los restaurantes.
Turismo de bienestar: Modalidad turística con potencialidades de crecimiento en el estado de Sinaloa, México
Authors: Arámburo-De-los-Ríos Januario , Bueno-Fernández Mario Mitsuo , De-La-Paz-Rosales María Teresa de Jesús , Ochoa-Balcázar Mónica Araceli
Published: January 2025

En Sinaloa, México, el turismo se ha consolidado como un sector impulsor de la economía. A pesar de los recursos y atractivos que posee la región, la modalidad de turismo de bienestar aún posee un escaso reconocimiento. En este sentido, el objetivo de la investigación consiste en analizar los requisitos evaluados por los turistas de manera que contribuyan a potenciar el desarrollo del turismo de bienestar en el estado de Sinaloa. El estudio se sustentó en un enfoque mixto de tipo no experimental de nivel descriptivo. Los datos fueron obtenidos de encuestas aplicadas a turistas en salida en tres aeropuertos: 2 internacionales y uno nacional. Aunque el personal encuestado refieren no haber accedido a la modalidad de turismo de bienestar se evidencian actividades con ese enfoque. Se consideran factible las oportunidades de fortalecer la oferta turística asociada a la modalidad de turismo de bienestar en el estado de Sinaloa
La ética pública en la encrucijada: desafíos y perspectivas a la luz del pensamiento de Max Weber
Authors: Barrera Linda Anita , Barrera Diana Angélica
Published: January 2025

Este estudio propone analizar la concepción de Max Weber sobre la ética política y su creciente relevancia en el panorama político contemporáneo. Se examina cómo la necesidad de una ética que frene el egoísmo político ha llevado a una revitalización de las ideas de Weber, especialmente en sociedades democráticas que buscan mayor transparencia. A través de un análisis de textos y documentos, se explora la dicotomía weberiana entre la ética de la convicción y de la responsabilidad. Se concluye que la ética pública debe ser constantemente redefinida en función de las dinámicas de poder de cada sociedad. En un mundo donde la ética en la política es cada vez más cuestionada, las ideas de Max Weber resurgen como una brújula necesaria. Al analizar la tensión entre nuestras convicciones personales y las responsabilidades del poder, Weber invita a reflexionar sobre los dilemas morales que enfrentan los líderes en la era contemporánea
La justa remuneración: Análisis jurídico de la reclasificación salarial de los funcionarios administrativos
Authors: Franco-Mendoza José Andrés , Hidalgo-Angulo Heidi Maria
Published: January 2025

La reclasificación salarial de los funcionarios administrativos del seguro social en Ecuador revela los hallazgos sobre la equidad salarial en el sector público. Se identificó una discrepancia entre las funciones de los trabajadores y la remuneración que reciben, lo que subraya la necesidad de abordar esta problemática. El objetivo es analizar la falta de reclasificación salarial de los funcionarios administrativos del seguro social, bajo el principio de igual trabajo, igual remuneración. El análisis basado en una metodología hermenéutico, mixta, muestra una brecha salarial entre lo que los funcionarios deberían recibir según la normativa y lo que perciben. Esta situación no solo afecta la calidad de vida de los trabajadores, sino que también repercute en la calidad del servicio que el IESS ofrece. Como resultado de la investigación el informe aboga por una revisión de las escalas salariales y la promoción de un entorno laboral más justo y equitativo.
Principio de interés superior del adolescente infractor y el derecho de defensa técnica
Authors: Viera-Herrada Lida , Tello-Yance Filoter
Published: January 2025

El método que se desarrolló en la presente investigación, se apoyó en el enfoque cuantitativo, lo que permitió establecer el análisis del objeto de estudio. Se empleó un diseño bibliográfico de tipo documental; la población de estudio se basó principalmente en trabajos arbitrados, documentos escritos y textos. Además, se llevó a cabo la revisión sistemática, que utilizó un protocolo que permitió organizar la información. Se realizó en dos fases: se revisaron los títulos y resúmenes y se confirmó su idoneidad, se analizó y revisó el texto completo. En conclusión, el principio de interés superior del adolescente infractor es fundamental en el ámbito legal y se refiere a la consideración prioritaria de garantizar el bienestar y desarrollo integral de los menores en cualquier decisión que los afecte.
Stateless by Chen Tienshi Lara, Translated by Louis Carlet (National University of Singapore Press 2024) 236 Pages. Price SGD36.00. ISBN 9789813252325
Authors: Napaumporn Bongkot
Published: January 2025

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Towards Equitable, Transparent and Evidence-based Malaysian Citizenship Law Amendments: Taking Stock of Remaining Risks of Statelessness and Exclusion
Authors: bt Mohamed Razali Rodziana , Chin Sia Chin
Published: January 2025

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Recognition of the Status of Stateless Persons and Right of Residence for Palestinians in Belgium: Applying the Principle of res judicata to Avoid Divergences among Courts
Authors: Bittoni Giulia
Published: January 2025

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Demonstration of enhanced Er luminescence in nanobeam photonic crystal nanocavities based on Er,O-codoped GaAs
Authors: Fang Zhidong , Kajii Hirotake , Kondow Masahiko , Fujiwara Yasufumi , Tatebayashi Jun
Published: January 2025

We employ a nanobeam photonic crystal (PhC) cavity with a central defect to improve its quality (Q-) factor, in order to enhance Er luminescence. Detailed numerical simulations are conducted to investigate the optimization process of the nanobeam PhC and a maximum Q-factor of 7.8 × 106 with a mode volume of 0.58 (λ/n)3 is obtained by optimizing the cavity design. The nanobeam PhC cavity with GaAs:Er,O as an active component is fabricated based on the simulation results. One of the cavity modes from the nanobeam PhC is perfectly coupled to Er luminescence at 1537 nm, and all of the cavity modes that appeared in the experimental results were consistent with the numerical simulations. A 4.6-fold enhancement of Er luminescence attributed to the coupling to the cavity mode is demonstrated with a Q-factor of ∼5500.
PERCEPÇÕES DO ENSINO SOBRE POPULAÇÕES LGBTQIAPN+ NA GRADUAÇÃO DE MEDICINA
Authors: Santin Sadi Bruno Freitas , Silva Fernanda Clara da , Silva Júnior José Antonio da , Fernandes Thales Allyrio Araújo de Medeiros , Fonseca Álvaro Micael Duarte , Nascimento Ellany Gurgel Cosme do
Published: January 2025

Introdução: Na formação em medicina, as temáticas gênero e sexualidade são pouco abordadas, o que contribui para o desconhecimento e a disseminação do preconceito entre os profissionais de saúde em lidar com pessoas LGBTQIAPN+. Objetivo: Avaliar as percepções entre discentes e docentes de medicina da Universidade do Estado do Rio Grande do Norte sobre questões de especificidades ligadas às populações LGBTQIAPN+. Metodologia: Trata-se de uma pesquisa descritiva e transversal, realizada por meio de formulários eletrônicos com discentes e docentes. Foram avaliados conhecimentos sobre conceitos das populações LGBTQIAPN+, abordagem da temática na graduação e percepções sobre preconceito. Resultados/Discussão: Observa-se que estudantes do internato autodeclarados LGBTQIAPN+ perceberam/presenciaram mais preconceitos durante a graduação em detrimento dos demais. Os dados apontam que 73% dos docentes não abordaram sobre sexualidade e gênero, mesmo 95,5% deles concordando que o assunto traz consequências positivas à prática médica. Conclusão: As percepções acerca da população LGBTQIAPN+ mostram a necessidade de ampliar o debate, visando à melhoria do processo formativo de futuros profissionais da área. Urge a necessidade de sensibilizar as universidades em busca de um currículo que agregue minorias sexuais e de gênero em seus projetos pedagógicos, para que os alunos criem as habilidades necessárias.
A Transitivity Analysis of the Clause in SiLozi Language (K21)
Authors: Kapau Humphrey M. , Siame Pethias , Amoakohene Benjamin , Mambwe Kelvin , Kangwa Kennedy N.
Published: January 2025

The paper uses Systemic Functional Linguistics (henceforth SFL) to conduct a transitivity analysis of the clause in the siLozi language (K21) spoken in Zambia. The paper explores how the experience of the material and non-material world is construed through the grammar of the clause. The paper draws insights from Martin and Rose’s (2003) SFL to analyse the clause in siLozi in terms of what kind of clausal activities are undertaken in the siLozi clause’s PRTs, PRSes and CIRs; how the PRTs in these PRS-types are described; how they are classified and what they are composed of. The transitivity study of the clause in siLozi reveals that just like in English, the siLozi language expresses its clausal experience through the three major PRS-types namely MaPs, MePs and RePs. The minor PRS-types – VePs, BePs and ExPs – not only exist in siLozi but also construe experience both uniquely and also similar to English. Furthermore, the discourse structures in the process-types are deliberately selected and situated for various reasons. The findings have implications in using SFL transitivity in the teaching of some aspects of grammar such as comprehension in siLozi in schools in Zambia and in other countries like Namibia where siLozi is taught.
Meta-Analysis of Transfection
Authors: Ahmad Sharique , Srivastava Priyesh , Ibrahim Mohd. , Bano Beenish , Khan Mehnaz , Shamim Faraz
Published: January 2025

Transfection is a critical technique for introducing nucleic acids—such as DNA, RNA, or oligonucleotides—into cells and plays a pivotal role in diverse research fields, including gene therapy, recombinant protein production, and functional genomics. This meta-analysis examines the fundamental mechanisms, methodologies, and challenges associated with transfection, highlighting advances in both viral and non-viral delivery systems, optimization techniques, and clinical applications. Viral vectors, including adenovirus, retrovirus, and lentivirus, offer high efficiency and are frequently used in gene therapy applications, while non-viral methods, such as lipid-mediated transfection, polyethylenimine (PEI), dendrimer complexes, electroporation, microinjection, and biolistic delivery, provide safer alternatives but often exhibit lower efficiency, necessitating optimization. Lipid-based transfection remains one of the most widely used methods, particularly lipofection, due to its ease of use and efficiency in commonly used cell lines like HEK293 and HeLa cells. Electroporation is effective for challenging cell types, such as primary neurons and stem cells, though high cell mortality rates necessitate careful optimization. Transfection has significantly contributed to gene therapy, particularly for genetic disorders such as cystic fibrosis, hemophilia, and spinal muscular atrophy, with viral vectors employed in CAR-T cell therapy for cancer treatment showing promising results in hematological malignancies. Recent advances in mRNA transfection have revolutionized vaccine development, exemplified by mRNA vaccines for COVID-19, demonstrating the potential for further therapeutic applications. However, challenges remain, including achieving high transfection efficiency while maintaining cell viability, especially in primary cells and stem cells, which are more resistant to transfection than immortalized cell lines. Cytotoxicity and off-target effects limit the clinical utility of transfection, particularly in gene therapy, where insertional mutagenesis poses significant safety risks. The cost of scaling transfection for therapeutic applications, such as CAR-T cell production, remains prohibitive. Future research will focus on overcoming these limitations while advancing the clinical applications of transfection for therapeutic gene delivery and personalized medicine. Overall, as new materials, technologies, and optimization strategies are developed, the efficacy, safety, and applicability of transfection techniques will likely improve, enhancing their role as cornerstones of molecular biology and biotechnology.
Obturator Traumatic Hip Dislocation: A Case Report
Authors: Benyass Youssef , Laghouagha Otman Oulad , Boukhriss Jalal , Benchebba Dris , Chafry Bouchaib
Published: January 2025

Pure anterior dislocation of the hip in its obturator variety is extremely rare. It typically results from high-energy trauma and can jeopardize the functional prognosis of the hip if reduction is not performed urgently. We report the case of a motorcyclist who sustained an isolated anteroinferior (obturator) hip dislocation. The patient underwent reduction 4 hours after the trauma, with good clinical and radiological outcomes observed at an 18-month follow-up.
Aligner Treatment in Class II Malocclusion Patient by Distalisation with Invisalign: Case Report
Authors: Qalalwa Mahmoud , Hajjem Ala , Dallel Ines , Amor Wiem Ben , Tobji Samir , Amor Adel Ben
Published: January 2025

Distalization is a common orthodontic technique used to address Class II malocclusions, particularly those where there is an overjet due to maxillary protrusion. It’s performed to correct average to moderate class 2 malocclusions (<3mm) by retracting the maxillary teeth. This technique should be preferred in patients presenting a class II malocclusion due to maxillary protrusion or in adult patients undergoing compromise treatment. The following case report describes an adult female patient with class II subdivision in the left side treated by clear aligner (invisalign) by distalization and class II elastics. Sequential distalization protocol was used starting with the second molar, once the second molar has moved two-thirds of the desired distance, the first molar is distalized, followed by the premolars and canines. Finally, the four incisors are retracted to complete the treatment.
Analysis of Mental Foramen Using Cone Beam Computed Tomography for Gender Determination in a Sample of Yemeni Population
Authors: Najjar Latifa A. Al- , Al-Eryani Reema A.
Published: January 2025

Aim: To analyze the mental foramen dimensions and location for gender determination in a sample of Yemeni population. Methods: This is a retrospective study performed on 420 maxillofacial CBCT scans, 210 males and 210 females with age ranged from 20 to 60- years old. Osteometric analysis of the dimensions, shape and position of the mental foramen was performed. Results: In comparison between males and females, all mental foramen (MF) measurements were statistically significant except at the distance from the superior mental foramen to the alveolar crest. The all measurements of males were higher than females. MF with round shape was the most common between both males and females. The most common location of the MF was presented below the apices of the 2nd premolars. Conclusions: We can be concluded that the vertical and horizontal dimensions the MF and the distance from the lower border of the MF to the lower border of the mandible exhibits gender dimorphism in the Yemeni population. The shape and horizontal position of the MF do not show any difference denoting that they cannot be used for identification of gender.