bluuebunny/crossref_metadata_2025 huggingface dataset:
Antidiarrheal Activity of The Combination of Ethanol Extracts of Turmeric Rhizomes, Gall oak Leaves, Guava Leaves and Meniran Herbs
Authors: Wijaya Sumi , Soegianto Lisa
Published: July 2018

Diarrheal disease is an endemic disease in Indonesia and also a potential disease that can cause death. In practice, the use of traditional medicines derived from plants still being considered by society due to its viability, economic factors and safety reasons. Several plants worked as antidiarrheal agents with the mechanism actions of (1) antibacterial (inhibited the growth of Escherichia coli, Shigella dysenteriae, Shigella flexneri, Staphylococcus aureus and Salmonella Typhi); (2) reduced the contraction of intestinal as results in the reduction of pain and the reduction of frequency of defecation or; (3) both mechanism of actions. Thus the purpose of the present study is to evaluate antidiarrheal activity of the combination of plant extracts which have been proved to have antidiarrheal activity.  Turmeric (Curcuma domestica) rhizomes, gall oak (Quercus lusitanica) leaves, guava (Psidium guajava) leaves and meniran (Phyllanthus niruri) herbs were used for this combination. The purpose of this combination was to minimize the doses (based on literature reviews turmeric at 5% and Meniran 10% inhibited the growth of Escherichia coli and Staphylococcus aureus, meanwhile guava leaves at 150 mg/kg BW and gall oak leaves at 10% reduced diarrhea in animal tested). Maceration was chosen for the extraction method using ethanol 96% as the solvent. Protection and transit intestinal method with loperamide HCl as comparison drug and castor oil for the induction of diarrhea were used for antidiarrheal activity, meanwhile diffusion and dilution methods using, inhibition zones, minimum inhibition concentration and minimum bactericidal concentration parameters were used for antibacterial activity. Tetracycline HCl with the concentration of 30 µg was used for the control. The results revealed that the combination of plant extract with the doses of 200 mg/KgBW (1:1:1:1) reduced diarrhea in mice with relaxation of smooth muscle and showed weak antibacterial effects on Eschericia coli and Staphylococcus aureus but strongly inhibited the growth of Salmonella Typhi.
Analisis Nilai Tambah Dan Sistem Pemasaran Lidah Buaya di Kabupaten Bogor
Authors: Suprabowo Rizky Lutfi , Winandi Ratna , Jahroh Siti
Published: July 2018

Produksi komoditas lidah buaya di Kabupaten Bogor sampai saat ini mengalami penurunan, meskipun pernah dicanangkan menjadi daerah pengembangan komoditas lidah buaya. Penelitian ini bertujuan untuk menganalisis nilai tambah dalam usaha pengolahan produk lidah buaya, serta menganalisis sistem pemasaran lidah buaya dari petani hingga konsumen akhir. Hasil penelitian ini dijelaskan secara deskriptif kualitatif dan kuantitatif. Komoditas lidah buaya dari petani di Kabupaten Bogor telah diolah menjadi produk olahan seperti jus, koktail, rainbow cake, kerupuk dan teh kulit lidah buaya. Berdasakan perhitungan nilai tambah dengan metode hayami, produk olahan rainbow cake memiliki nilai tambah paling besar. Terdapat 6 saluran pemasaran lidah buaya di Kabupaten Bogor, yaitu 3 saluran pemasaran grade A dan 3 saluran pemasaran grade B. Petani dalam memasarkan lidah buaya masih melibatkan tengkulak. Saluran pemasaran 1, 2 dan 4 adalah saluran yang mudah diakses oleh petani. Saluran pemasaran 2 (Petani → Suplayer → Supermarket → Konsumen) merupakan saluran yang relatif efisien, karena harga yang diterima petani relatif lebih tinggi, nilai marjin saluran pemasaran yang relatif lebih kecil dan nilai farmer’s share yang relatif lebih tinggi dari saluran yang lainnya.
Konsumsi Ekstrak Secang (Caesalpinia sappan L.) Terhadap Volume Urin Tikus Putih Jantan Galur Spraque Dawley
Authors: Pertamawati Pertamawati , Sriningsih Sriningsih , Fahrudin Fahri , Efendi Julham
Published: July 2018

Secara empiris secang (Caesalpinia sappan L.) dimanfaatkan sebagai bahan untuk mengatasi penyakit, namun bagaimana pengaruhnya terhadap pengeluaran urin belum diketahui. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi ekstrak secang terhadap pengeluaran urin. Percobaan dilakukan terhadap hewan coba tikus putih jantan galur Spraque dawley dengan sampel uji ekstrak etanol 96% kulit kayu secang. Hewan coba dibagi dalam 7 kelompok, masing-masing terdiri dari 6 ekor, yaitu kelompok normal, kelompok positif (Furosemide 10mg/200g BB), kelompok  negatif (air 2ml/200g BB), kelompok sampel uji dosis I (62.5 mg/kg BB), dosis II (125mg/kg BB), dosis III (250mg/kg BB) dan dosis IV (500mg/kg BB), tigapuluh menit setelah pemberian sampel uji, hewan coba diberi air minum 4ml/200g BB dilakukan melalui sonde lambung, selanjutnya hewan coba dimasukkan ke dalam kandang metabolit selama 16 jam (overnight). Hewan coba dengan dosis II menghasilkan volume urin paling besar (8.00 mL) yaitu hampir dua kali lipat dibandingkan urin yang dihasilkan oleh kelompok normal (4.50 mL) Volume urin berkurang jika konsumsi ekstrak secang bertambah pada dosis III dan IV. Disimpulkan bahwa hewan coba yang diberi ekstrak kulit secang dengan dosis 125 mg/kg BB (dosis II) rata-rata mampu mengeluarkan urin lebih banyak daripada hewan coba dalam kelompok lainnya.
Aktivitas Formulasi Biji Jarak Pagar dan Pare terhadap Spermatogenesis pada Tikus Wistar
Authors: Nurhadijah Lilis , Perdana Alfa A , Widyawati Widyawati , Setiyoko Ferian A , Utami Baiq NM , Dewi Tri Isyani Tungga , Suparto Irma H
Published: July 2018

Bahan alam yang dapat menghambat spermatogenesis merupakan suatu alternatif untuk kontrasepsi pria. Penelitian ini bertujuan mengevaluasi formulasi optimum berbasis biji jarak pagar dan buah pare yang dapat menginhibisi spermatogenesis. Bahan sampel dimaserasi alkohol 70% untuk memperoleh ekstrak kasar. Ekstrak diujikan pada tikus Wistar jantan dewasa sebanyak 30 ekor dan dibagi menjadi enam kelompok secara acak (n=5 ekor). Kelompok I sebagai kontrol memperoleh pelarut akuades; kelompok II dan III secara berurutan memperoleh ekstrak biji jarak dan pare dengan dosis 50 mg/kgBB. Tiga kelompok lainnya, yaitu IV, V, dan VI memperoleh formulasi gabungan dengan rasio ekstrak biji jarak pagar dan pare 1:3, 3:1 serta 1:1, secara berurutan. Perlakuan diberikan per oral satu hari sekali selama 48 hari sesuai dengan siklus spermatogenesis. Pada akhir perlakuan, pemeriksaan sperma untuk konsentrasi dan kualitasnya serta bobot testis. Hasil uji rendemen ekstrak biji jarak pagar dan buah pare secara berurutan sebesar 6.11 % dan 3.32 %. Senyawa fitokimia yang terdapat pada ekstrak pare dan biji jarak pagar antara lain, alkaloid, fenol, flavonoid, tanin, saponin, triterpenoid, dan steroid. Efek ekstrak terhadap bobot testis dan konsentrasi sperma tidak ada perbedaan yang nyata antar kelompok (ANOVA P >0.05) sedangkan untuk kualitas motilitas sperma ada kecenderungan menurun pada formulasi ekstrak biji jarak dan buah pare (1:3).
Editorialboard dan Kelengkapan Jurnal
Authors: Rafi Mohamad
Published: July 2018

Puji dan syukur kami ucapkan kepada Tuhan Yang Maha Esa berkat rahmat dan hidayahNya, Jurnal Jamu Indonesia Volume 3 No 1 dapat diterbitkan. Redaksi mengucapkan terima kasih kepada seluruh penulis atas partisipasinya dalam berbagi hasil penelitiannya melalui publikasi di Jurnal Jamu Indonesia. Jurnal ini merupakan media untuk diseminasi hasil penelitian yang berkaitan dengan jamu di Indonesia.

Naskah dalam edisi ini membahas berbagai tumbuhan obat tradisional untuk pengujian terhadap suatu aktivitas. Ekstrak metanol Rhizopora apiculata sebagai biosensor penghambatan aktivitas tirosinase menggunakan elektrode pasta karbon termodifikasi ferosena dan zeolit, aktivitas yoghurt kacang komak (Lablab Purpureus (L.) Sweet) sebagai antihiperglikemia, dan aktivitas formulasi biji jarak pagar dan pare terhadap spermatogenesis pada tikus wistar. Selain itu, peningkatan kandungan kurkumin pada tumbuhan temulawak juga diamati serta formulasi jamu baru yang memiliki efek hipoglikemik, menentukan toksisitas, dan profil kimia jamu dengan metode statistika dan machine learning.

Kontribusi publikasi peneliti-peneliti dan pejuang Jamu Indonesia terus kami harapkan untuk dapat disampaikan di dalam Jurnal Jamu Indonesia ini. Semoga jurnal ini senantiasa dapat menjadi fasilitas bagi para peneliti dan ilmuwan untuk memudahkan pendistribusian informasi ilmu pengetahuan mengenai jamu melalui tulisan-tulisan yang dapat dipublikasi. Semua hasil karya tersebut akan diarsipkan sebagai dokumentasi berharga demi terjaganya informasi yang dapat menjadi sumber pengembangan ilmu pengetahuan di masa depan.

 

Mohamad Rafi

Ketua Dewan Redaksi
La formación inicial de Pedro Henrí­quez Ureña en República Dominicana (1884-1901)
Authors: Mendoza Bolaños Daniel
Published: July 2018

Este artí­culo describe la etapa menos conocida en la vida de Pedro Henrí­quez Ureña (1884- 1914), uno de los humanistas latinoamericanos más importantes del siglo XX. Describe los primeros pasos de este intelectual en la literatura, sus lecturas infantiles, escritos inaugurales y el influjo que tuvo en su formación el ambiente cultural y educativo de República Dominicana de finales del siglo XIX. Asimismo, incursiona en la vida familiar y el ideario pedagógico de Salomé Ureña y Francisco Henrí­quez, padres de Pedro, quienes formaban parte del sector ilustrado dominicano que contribuyó al desarrollo nacional con su labor educativa y literaria. Pedro Henrí­quez Ureña creció acompañado de esta élite y fue influido por la búsqueda de la identidad cultural dominicana, que tuvo sus fundamentos en la reforma educativa propuesta por Eugenio Marí­a de Hostos.
El intercambio académico entre México y América Latina durante el cardenismo. Problemas, debates y actores
Authors: Rivera Mir Sebastián
Published: July 2018

El presente artí­culo se propone explorar los principales cuestionamientos historiográficos que se pueden plantear en torno al intercambio académico internacional realizado durante la presidencia de Lázaro Cárdenas. Este primer acercamiento busca construir un marco analí­tico desde el cual observar esta temática, y en lugar de esbozar resultados finales concluyentes, en las siguientes páginas se intenta profundizar en las preguntas que dicho proceso plantea a la historia de la educación. Este tema ha sido una de las constantes en el ámbito universitario, sin embargo, la historiografí­a escasamente ha profundizado en él. Por este motivo, se recurre a un abanico metodológico y de fuentes para analizar cuáles son las potencialidades de emprender su estudio de manera sistemática.
José Juan Espinosa Zúñiga (2017), La Dirección Federal de Seguridad y sus actividades de espionaje en la Universidad Autónoma de Zacatecas, 1977, Zezen Baltza/Instituto Zacatecano de Cultura, Sindicato de Personal Académico de la Universidad Autónoma de Zacatecas, Secretaría de Cultura/Conacyt, Zacatecas
Authors: Terán Fuentes Mariana
Published: July 2018

Como la institución de educación superior pública, la Universidad Autónoma de Zacatecas (UAZ) representa la oferta educativa más ambiciosa del estado de Zacatecas, tanto por sus indicadores en calidad y competitividad, como por la cobertura respecto de la población de dicha entidad. En 2018, la UAZ cumple cincuenta años de su creación como universidad pública y autónoma, eslabón que habrá que reconocer dentro de la cadena que representa su largo pasado como Casa de Estudios de Jerez desde 1832, Instituto Literario de Zacatecas, Instituto Científico de Zacatecas y el logro de su autonomía en 1959. Una institución que ha permitido, a lo largo de casi dos siglos, formar tanto a la élite política durante el siglo XIX, como a una creciente población de diferentes sectores sociales a partir de la década de los años setenta.
A New Concept Generated by Commoditizing Animals: Egological tourism
Authors: TAŞPINAR Oğuz
Published: July 2018

Animals have been used to amuse people for
thousands of years, trained for dolphin shows, circus and similar tricks found
amusing by viewers/participants, and have suffered pain in the activities that
are so-called “sports”, such as rodeo, horse racing, greyhound racing,
bullfighting and camel wrestling; i.e., they are turned into a performer and
racer by humans (Regan, 2007). What Regan says above basically addresses the commoditization
of animals. Undoubtedly, tourism and its components incorporated in capitalism
are to blame. This is why, in his book and philosophy, Regan asks to empty the
cages and pools and wishes to free all animals involved in any shows. However,
this could only come true when tourism ceases to see animals as a product and
market them to tourists/visitors and the consumers wish to debar from such amusement
Problems of Interregional and Intersectoral Allocation: The Case
of Pakistan
Authors: Macewan Arthur
Published: July 2018

Many countries have "regional problems". Income and political
power are allocated unequally among regions with no significant change
over time, and these inequities are a source of political tension. The
regional problem in Pakistan is especially severe because the peculiar
geographic nature of Pakistan makes the issue so visible1. Economic
planners in Pakistan and other poor countries are often as¬signed the
task of designing programmes to bring about income parity among regions.
In doing so, planners confront several analytic and technical prob¬lems.
The principal difficulty is how to allocate resources so as to best
conform to political preferences of policy-makers. In this context it is
desirable to dis¬cover and exploit the comparative advantages of the
regions. Regional com¬parative advantages, in turn, are dependent upon
the regional distribution of resources and upon political preferences as
to the regional allocation of welfare.
Private Foreign Investment in Pakistan (Notes &
Comments)
Authors: Chaudhry Shahid Amjad
Published: July 2018

Private foreign investment in Pakistan is regulated by the
government's statement of industrial policy issued in 1959 which
recognises, welcomes, and facilitates the inflow of private foreign
investment in the country. In order to attract foreign investors, the
government offers liberal incentives and concessions. In addition all
profits are repatriable at the official rate of exchange. An attempt has
been made in this note to determine the size and nature of private
foreign investment in relation to the rest of the economy and to examine
the inflows of private investment and remittances of profits, dividends,
etc., made abroad.
Development Projects Observed by A. O. Hirschman. The Brookings
Institute, 1969.
Authors: Rotner Evan R.
Published: July 2018

There has been persistent dissatisfaction in Pakistan, both at
official and unofficial levels, with the performance of public-sector
projects. While there are some notable successful exceptions, on the
whole, projects take a long time to get started; there are large
over-runs on estimated investment costs; the period of investment often
proves to be longer than expected; technical diffi¬culties trouble
production and anticipated markets do not materialize. It is
questionable in some cases whether even the original conception of the
project, as costed and conceived, would have resulted in a net benefit
to the economy. In every sector and in both wings of the country there
are examples of projects with such problems.
Economics of Fertilizer Application to Wheat Crop: The Results of
a Survey in Lyallpur District (Notes and Comments)
Authors: Quraishi Barkat Ali , Khan Muhammad Jameel
Published: July 2018

Reliable knowledge about the contribution of various factors
responsible for increasing agricultural production is indispensable for
planning. This holds particularly for the fertilizer use, which has been
recognized as one of the quickest and, perhaps, the cheapest means for
increasing agricultural produc¬tion. In Pakistan the emphasis on planned
development is gaining momentum and for this purpose more data and
fuller information on fertilizer response are becoming increasingly
essential. The Agricultural Research Stations in the country have been
conducting experiments with a view to determining the extent to which
the cropped yield may increase due to the application of fertilizer. But
such experiments, because of their somewhat controlled nature in respect
of certain factors, obviously can¬not tell us with a desired measure of
accuracy as to what is actually happening at millions of private farms
throughout the country. And, as such, the planning in this regard is apt
to be wrong.
The Cost of Draft Animal Power in West Pakistan
Authors: Bose Swadesh R. , Clark Edwin H.
Published: July 2018

Most of the writings on the benefits of agricultural
mechanization begin with an analysis of the savings in cost which will
be achieved if mechanical rather than animal power is used for certain
agricultural operations. There have been some studies, mostly in India1,
which have tried to measure these savings. The mechanization issue
cannot, however, be judged solely on this criterion. In addition to
bullock displacement, mechanization is likely to involve farm-labour
displacement. As we have argued in a recent paper [2], the extent of
such labour displacement and its social costs are among the basic issues
which should be considered before going from bullocks to tractors. But
leaving aside these other issues, before one can measure the cost
advantage of mechanical power over animal power, one must define what
the costs are and how they should be measured. For mechanical power,
such measurement of costs is not difficult. We know the cost of
importing the tractor and its imple¬ments. We know the costs of fuel
which we have to pour into the machine every time we want it to do
something. The first is clearly a fixed cost and the second, after
adding repairs, maintenance, the driver's pay, etc., is clearly a
vari¬able cost.
Terminal-Year Investment In Finite-Horizon Planninq Models (Notes
& Comments)
Authors: Porter Richard C.
Published: July 2018

A common problem of finite-horizon planning models is that
there is no logical determinant of investment in the final year (s).
Where post-horizon production is not valued by a model, later-year
investment, whose sole function is creation of capacity for post-horizon
output, looks as incongruous as last rites for an atheist. A number of
artificial devices have been developed to handle this difficulty1, but
one predominates: to assume that terminal-year investment is a function
of terminal-year output. The purpose of this note is to show: 1) how
varied and arbitrary are the assumed functions (Section I); 2) that the
terminal-year variables and the apparent feasibility of the resulting
Plan are highly sensitive to the choice of function (Section II); and 3)
that the arbitrariness of functional form is inevitable in the sense
that generally acceptable criteria do not much restrict the choice
(Section III). Throughout this note, we shall neglect four complexities
that are not essential to the problem at hand. One, the marginal
capital-output ratio (
The Location of Industry
Authors: Papanek Gustav F.
Published: July 2018

Location theory must be one of economic theory's least applied
branches. The theoretical literature on industrial location is
extensive, the empirical evidence sparse. There are many reasons for the
gap between theory and evidence. It has proved difficult to measure the
impact of location on costs and returns since data are not available on
enterprises with similar production functions, but different locations.
The responses of industrialists to questions about location decisions
give unreliable results since sample surveys of industrialists are
inevitably biased by the exclusion of those who considered but rejected
a particular location or who failed because they made the wrong
locational decisions. Surveys also suffer from rationalizations and
ex-post explanations. Even if a location decision was based on a rumour
or accident, an industrialist may well develop a more logical
explanation afterwards. Surveys also obtain a picture of the average
reason for investment over time and it is difficult to deter¬mine the
predominant reason at any particular time. Without a time profile of the
reasons for decisions, one cannot link them to causal factors which
undoubt¬edly changed over time. Dynamic and accidental factors are
especially important in location decisions and are difficult to analyze.
For instance, the first factory in an industry may be located because an
empty building exists. Later investors in the new industry may locate
near the pioneer just because they draw assurance from his success. Both
the initial accident and the later nonrational elements are unlikely to
be uncovered by a survey or other techniques.
Population and Food Supply: Essays on Human Needs and
Agricultural Prospects Edited by Sir Joseph Hutchinson. Cambridge
University Press, Cambridge, 1966.
Authors: Raquibuzzaman M.
Published: July 2018

This book is a collection of lectures on population and
agricultural prospects delivered in Cambridge University, England,
during 1966 and 1967 by a group of scholars with diverse backgrounds.
Some of them are demographers and economists, some others are
nutritionists and physiologists. Probably because of the specific nature
of the population problem and food supply or perhaps because these
lectures were not originally prepared with the intention of publishing
them together in a book form, there appears to be a lot of repetition of
ideas by the individual lecturers. The book is, however, interesting as
it covers all the important aspects of the population problem and the
problem of keeping up food supply.
Price Incentives for the Production of High-Yielding Mexican
Varieties of Wheat
Authors: Hussain Sayed Mushtaq
Published: July 2018

After stagnating in the 1950's, agricultural production in
West Pakistan rose substantially in the early 1960's because of
increased area under cultivation and higher crop yields made possible
through greater availability of controlled water and the use of
fertilizers. Since the mid-sixties, another important source of
agricultural growth has been added, namely, the development and spread
of high-yielding varieties of wheat, rice and maize. The discovery and
develop¬ment of high-yielding seeds (HYS) amount to a technological
change and this has created a very large potential for raising the
production of certain crops, provided the necessary inputs are properly
used. Agricultural experts have predicted that with the adoption of the
new HYS and the realization of their full-yield potential, the current
problem of 'food shortage' will change into a problem of 'food
surplus'.
International Economic Assistance in the 1970's — A Critique of
Partners in Development (Review Article)
Authors: Islam Nurul
Published: July 2018

Foreign economic aid is at the cross-roads. There is an
atmosphere of gloom and disenchantment surrounding international aid in
both the developed and developing countries — more so in the former than
in the latter. Doubts have grown in the developed countries, especially
among the conservatives in these countries, as to the effectiveness of
aid in promoting economic development, the wastes and inefficiency
involved in the use of aid, the adequacy of self-help on the part of the
recipient countries in husbanding and mobilising their own resources for
development and the dangers of getting involved, through ex¬tensive
foreign-aid operations, in military or diplomatic conflicts. The waning
of confidence on the part of the donors in the rationale of foreign aid
has been accentuated by an increasing concern with their domestic
problems as well as by the occurrence of armed conflicts among the poor,
aid-recipient countries strengthened by substantial defence expenditure
that diverts resources away from development. The disenchantment on the
part of the recipient countries is, on the other hand, associated with
the inadequacy of aid, the stop-go nature of its flow in many cases, and
the intrusion of noneconomic considerations governing the allocation of
aid amongst the recipient countries. There is a reaction in the
developing countries against the dependence, political and eco¬nomic,
which heavy reliance on foreign aid generates. The threat of the
in¬creasing burden of debt-service charge haunts the developing world
and brings them back to the donors for renewed assistance and/or debt
rescheduling.
Manual of Industrial Project Analysis in Developing Countries,
Vol. II by I. M. D. Little and James A. Mirriees, OECD, Paris,
1969.
Authors: Wellisz Stanislaw
Published: July 2018

The Little-Mirrlees Manual of Industrial Project Analysis in-
Developing Countries is divided into two parts; the first of which is
addressed "to the senior administrator or politician, who should
understand the broad lines of what is implied by operating a system of
social cost-benefit analysis"; and the second "to those who will
actually make project evaluations, and teach others how to make them".
In fact, the two parts make an integral whole, since the first part of
the book raises several broad issues the answers to which are given in
the second part. For instance, on page 44 the "senior administrator or
politician" is told of the dilemma of the choice between
employment-generating and rein¬ vestment-generating projects; a project
which employs a lot of labour will get higher marks because it results
in a lot of consumption by the poor now. But the incomes generated by
such a project will be almost entirely spent. There will, therefore, be
little savings generated and so such a project will contribute little to
further investment, which, in turn, yields future consumption", while a
capital-intensive project with a high reinvestment rate makes a greater
contribution to the future, but a smaller one to present welfare. Unless
the "senior administrator or politician" is willing to read difficult
and often obscure discussions in Partll (Ch. 13) he will have no idea
how to go about resolving the dilemma. There is little fear, however,
that the nonprofessional reader will get through Part I, not to speak of
Part II. To be sure, the authors give a warning that "some of the
chapters of Part I may be a little academic for the senior man who has
become familiar with economics by practical exposure and does not want
to feel that he is going back to school", but they grossly underestimate
the gap between the layman's ability to cope with abstract concepts and
their "own ability to use plain English. I wonder what the intelligent
layman is to make of the following passage which occurs on page 41 and
which I chose almost at random:
Zersägte Köpfe. Die Transformation antiker Porträts zu monumentalen Gemmenbildern im 18. Jahrhundert
Authors: Grassinger Dagmar
Published: July 2018

Im 18. Jahrhundert wurden fragmentiert erhaltene antike Porträtköpfe bisweilen in der Längsachse geteilt und beide Hälften separat als Profilköpfe auf marmorne Hintergründe montiert. Diese Marmorhintergründe hatten häufig die Form ovaler Medaillons mit mehr oder weniger aufwendig profilierten Rahmen. Durch diese Restaurierungspraxis entstand mit solchen Porträtmedaillons eine Reliefgattung, die uns in dieser Form aus der Antike selbst so gut wie gar nicht überliefert ist, die aber im 18. Jahrhundert offenbar einen Nerv der Zeit getroffen hat. Die Porträtmedaillons mit ihren leicht erhabenen Profilköpfen können als monumentalisierte Gemmenabdrücke in Stein verstanden werden. Angeregt wurden sie wohl durch zahlreiche zeitgenössische Gemmenpublikationen in opulenten Stichwerken und den durch diese generierten „Gemmenblick“ der Betrachter. So geben diese zu monumentalen Gemmenabdrücken transformierten Porträthälften Aufschluss zu Wahrnehmungs- und Sehgewohnheiten ihrer Entstehungszeit. Sie sind Teil eines ästhetischen Zeitphänomens, das antike Denkmäler durch den Umriss ihrer Formen definiert.
Social engineering of human resources and provision of medical services on leadership styles in hospitals
Authors: Rosak-Szyrocka Joanna
Published: July 2018

Paper present impact of human resources issues as well as issues related to provision of medical services on leadership styles in hospitals in Poland. In this study a descriptive research design was used and a quantitative research was conducted, which was based on the so-called BOST methodology. Surveys were conducted among department heads of 10 public hospitals of various referral systems from the Upper-Silesian Agglomeration providing various types of medical services (which shows a large variety of research sample) operating in Poland. The research showed that both improtance of service provision as well as human resources were not as important as they should be.
Obtaining of biomorphic composites based on carbon materials
Authors: Lisiecka Barbara , Bokůvka Otakar , Tański Tomasz , Krzemiński Łukasz , Jambor Michal
Published: July 2018

Aim of this paper is to present the properties of carbon preforms for the production of biomorphic composites. Carbon samples were obtained through pyrolysis of paulownia wood, replicating the microstructure of the cellulosic precursor. Many characterization methods such as Raman Spectroscopy, light microscopy, hardness tests and pore size analyzer detection were used to investigate the microstructure of the product as well as the pore size of carbon samples. Obtained results showed that the parts of early or late wood template play an important role in the pore size, specific surface area and pore volume of the product. This review aims to be a comprehensive description of the development of carbon chars: from wood templates and their microstructure to potential applications of biomorphic materials.
THE EFFICIENCY OF USING EDUCATION VIDEOS ON THE LINEAR PROGRAM MATERIAL AS OBSERVED IN VOCATIONAL HIGH SCHOOL STUDENTS’ MATHEMATICAL COMMUNICATION ABILITY
Authors: Zakiah Laela , Saomi Asy Syifa Nurul , Syara Rita , Hidayat Wahyu , Hendriana Heris
Published: July 2018

This research has a purpose to find out the efficiency of of using education videos to increase the vocational high school students’ mathematical communication ability. The method used for this research was a quasi experiment method where the researcher took two classes as research samples. The first class was the experimental class where the students were shown the education videos and the second class was the control class where the students were taught as usual. The materials which were used for this research was a linear program. The research’s populations were the tenth grade students of SMK AL-Halim Garut with class X Multimedia and X Teknik Komputer dan Jaringan (TKJ) (Class of Computer Techniques and Network)as the samples. From the result of the first normality data analysis test (Pre-test), it was found that the experimental class did not distribute normally, therefore, the research continued by using Mann Whitney’s experiment. Sig.0.456 > 0.05 was resulted from the count, therefore H0 was accepted, it meant that there was no difference between the experimental class and control class. Meanwhile, on the final test (Post-test), the scores of both classes did not distribute normally, therefore Mann Whitney’s experiment was used again to find out. Sig.0.000 > 0.05 was resulted from the count, therefore H0 was rejected. In conclusion, “The efficiency of the students’ mathematical communication ability who got the education videos was more effective than those who were taught as usual on the linear program material”
THE EFFECTIVENESS OF LEARNING PROGRAMS THROUGH BOY-BOYAN GAME TO DEPELOVE INTERPERSONAL AND INTRAPERSONAL INTELLIGENCE OF KINDERGARTEN STUDENTS KINDERGARTEN
Authors: Komala Komala
Published: July 2018

The objectives of this research is to know the effectiveness of learning program through Boy-boyan Game (traditional game from West Java Indonesia) to develope interpersonal and intrapersonal intelegency of  PHBS Kindergarten and NEO Mahardika Kindergarten students (TK). This research is motivated by the discovery of the potential development of interpersonal and intrapersonal intelligence of Kindergarten students which is not well developed and it’s need to be developed optimally by implementing learning programs Boyboyan game. To formulate the framework program and finding data as material preparation program, so in this study used quantitative approach with quasi experimental methods used against children in group B PHBS and NEO Mahardika that is consisting  20 students as control group 20 students as experiment group. The procedure consists of pre-field research, the implementation of the study, data analysis and reporting the result .Based on the research the researcher found the following result: First, the development of interpersonal and intrapersonal intelligence of kindergarten appeared to vary for each children. Second, the learning program found that the learning program through the traditional game formulations include: rational, goals, objectives and scopes. Third, learning programs through traditional games have a positive effectiveness to improve interpersonal and intrapersonal development of early childhood, from the average obtained that the average experimental group is greater than the control group. It  means that interpersonal and intrapersonal intelligence grouped experiment better than the control group or in other words the treatment in the experimental group in the form of learning through traditional games effective in improving interpersonal and intrapersonal intelligence of children. Based on the findings of the above the recommendation of this research is aimed to teachers of kindergarten should enhance the program in accordance with the curriculum related to the themes of learning certain to develop learning activities both theoretical study and practical for children, so that children are able to develop intelligence prominent/dominant in him. For further research should apply the kind of game where the more dominant towards the development of a child's intelligence so that it will appear to optimally increase interpersonal or intrapersonal intelligence of children.
Определение относительного содержания цисплатина в клетках по интенсивности флуоресценции акридинового оранжевого
Authors: Горошинская Ирина Александровна , Тарнопольская Ольга Владимировна , Качесова Полина Сергеевна
Published: July 2018

Методом флуоресцентной микроскопии исследовали интенсивность флуоресценции акридинового оранжевого, связанного с лейкоцитами крови человека, лабораторных животных и клетками лимфосаркомы Плисса крыс. Клеточную взвесь лейкоцитов делили на 2 части, в одну из которых добавляли цисплатин в конечной концентрации 0,1 мкг/мл и инкубировали в течение 20 – 60 мин. Затем добавляли акридиновый оранжевый и определяли среднюю интенсивность зеленой и красной флуоресценции клеток. Интенсивность флуоресценции акридинового оранжевого в зеленой области спектра была снижена в 3 раза в препарате клеток с цисплатином (p = 0,001). В красной области спектра различий по средней интенсивности флуоресценции клеток с цисплатином и без него не наблюдали. Результаты свидетельствуют о том, что определение интенсивности зеленой флуоресценции акридинового оранжевого, связанного с клетками, может быть тестом на присутствие в клетках цисплатина.
Сравнительная эффективность гепатотропной активности ремаксола и эссенциале Н при хронических вирусных гепатита
Authors: Павелкина В. Ф. , Амплеева Н. П.
Published: July 2018

Изучена гепатотропная активность ремаксола и эссенциале Н при хронических вирусных гепатитах (ХВГ) В и С: 45 больных получали препарат ремаксол (внутривенно капельно, 400 мл в сутки, 10 дней), 45 пациентов – эссенциале Н (внутривенно струйно, 5 мл в сутки, 10 дней). Эффективность препаратов оценивали по клинической симптоматике, активности АлАТ и АсАТ, уровню билирубина, щелочной фосфатазы, молекул средней массы (МСМ), общей и эффективной концентрации альбумина (ЭКА). Ремаксол при ХВГ оказывал гепатотропный эффект, сравнимый с эссенциале Н, но более эффективно купировал астеновегетативный, диспепсический, холестатический и интоксикационный синдром, что подтверждалось достоверно низкими значениями МСМ и высокими показателями ЭКА. Включение ремаксола в схему лечения больных ХВГ следует считать патогенетически обоснованным, клинически оправданным и перспективным.
Применение дельталицина в лечении пациентов с диабетической ретинопатией
Authors: Кресюн Наталья Валентиновна , Годлевский Леонид Семенович
Published: July 2018

В работе наблюдали 15 практически здоровых (средний возраст 31,7 ± 3,6 года) и 30 инсулин-зависимых больных сахарным диабетом (средний возраст 32,1 ± 4,0 года), из которых у 15 не было признаков ретинопатии и у 15 — средняя и выраженная пролиферативная ретинопатия. У пациентов с сахарным диабетом отмечалось увеличение латентного периода зрительного вызванного потенциала (ЗВП) (Р100) и снижение амплитуды (N75-P100), более выраженное во второй подгруппе, удлинение времени восстановления ЗВП. Применение дельталицина (одна ампула, содержащая 0,0003 г дельта сон-индуцирующего пептида, ежедневно интраназально на протяжении 2 мес) сокращало латентный период и увеличивало как амплитуду ЗВП и уменьшало период восстановления функциональной активности сетчатой оболочки после фотостресса.
Аномальная деполяризация пейсмекеров в области лакун легочных вен как источник аритмогенеза у крыс со сформировавшейся алкогольной кардиомиопатией
Authors: Цорин И.Б. , Смирнова С.Л. , Столярук В.Н. , Вититнова М.Б. , Колик Л.Г. , Крыжановский С.А. , Рощевская И.М.
Published: July 2018

Выявлено увеличение неоднородности деполяризации предсердий крыс с алкогольной кардиомиопатией
Антидепрессивноподобная активность циклопролиглицина
Authors: Абдуллина А.А. , Васильева Е.В. , Колясникова Ксения Николаевна , Ковалев Георгий Иванович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Количественное определение нового соединения с анксиолитической активностью ГМЛ-1 в таблетках
Authors: Илларионов Александр Анатольевич , Грушевская Любовь Николаевна , Сергеева Мария Сергеевна , Гаевая Людмила Михайловна , Пятин Борис Михайлович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Изучение влияния комбинации гимантана и пирибедила у мышей С57BL/6 c МФТП-вызванным паркинсоническим синдромом
Authors: Калинина Татьяна Сергеевна , Капица Инга Геннадиевна , Иванова Елена Анатольевна , Воронина Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Расстройства аутистического спектра и возможности лекарственной терапии
Authors: Капица Инга Геннадиевна , Иванова Елена Анатольевна , Воронина Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Структуроспецифические изменения тканевых уровней моноаминов после однократной внутрибрюшинной инъекции физрастора у крыс Wistar
Authors: Касабов К.А. , Кудряшов Никита Викторович , Наплёкова Полина Леонидовна , Наркевич Виктор Борисович , Кудрин Владимир Сергеевич
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Исследование острой токсичности препарата ГСБ-106
Authors: Алексеева Светлана Витальевна , Мирошкина Ирина Александровна , Волкова А.В. , Забродина Виктория Владимировна , Сорокина Александра Валериановна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Противоишемические цереброваскулярные эффекты S-амлодипина никотината в сравнении с мексидолом
Authors: Ким Галина Александровна , Ганьшина Тамара Сергеевна , Курдюмов Илья Николаевич , Масленников Денис Вадимович , Курза Елена Владимировна , Васильева Е.В.
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Изучение аллергизирующих свойств и иммунотоксичности препарата ГК-2
Authors: Коваленко Лариса Петровна , Журиков Руслан Владимирович , Коржова Ксения Витальевна , Кузнецова Ольга Сергеевна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Анксиолитик афобазол: влияние на когнитивное функционирование больных с тревожными расстройствами
Authors: Коваленок Татьяна Васильевна , Чепелюк А.А. , Метлина Марианна Вячеславовна , Телешова Евгения Сергеевна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Нейропсихотропные свойства низкомолекулярного димерного дипептидного миметика фактора роста нервов человека, ГК-2h
Authors: Котельникова Светлана Олеговна , Крайнева Валентина Александровна , Гарибова Таисия Леоновна , Гудашева Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Влияние афобазола и диазепама на связывание лиганда sigma-1 рецепторов в мембранных фракциях головного мозга мышей BALB/с при эмоционально-стрессовом воздействии
Authors: Курбанов Р.Д.
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Влияние 5-гидроксиадамантан-2-она, афобазола и нимодипина на кровоснабжение мозга крыс в условиях ишемического и геморрагического поражений
Authors: Курдюмов Илья Николаевич , Масленников Денис Вадимович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Проблемы рассогласования циркадианных ритмов. Фармакологическая коррекция нарушений
Authors: Литвинова Светлана Александровна , Воронина Татьяна Александровна , Калинина Татьяна Сергеевна , Иванова Е.А. , Капица Инга Геннадиевна , Неробкова Любовь Николаевна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Синтез и антиаритмическая активность N-[2-(1-адамантиламино)-2-оксоэтил]-N-(аминоалкил)амидов нитробензойных кислот
Authors: Лихошерстов Аркадий Михайлович , Крыжановский Сергей Александрович , Столярук Валерий Николаевич , Цорин Иосиф Борисович , Вититнова Марина Борисовна , Мокров Григорий Владимирович , Гудашева Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Оценка дифференцировочной активности димерных дипептидных миметиков 1-й и 4-й петли фактора роста нервов на культуре клеток феохромоцитомы крысы линии РС12
Authors: Антипова Татьяна Алексеевна , Николаев С.В. , Ревищин Александр Владимирович , Савченко Е.А. , Павлова Г.В. , Гудашева Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Анализ цереброваскулярного эффекта производных адамантана
Authors: Масленников Денис Вадимович , Ганьшина Тамара Сергеевна , Курза Елена Владимировна , Вальдман Елена Артуровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Оценка противоболевой и противовоспалительной активности гимантана в наружной гелевой лекарственной форме
Authors: Матюшкин Александр Иванович , Иванова Е.А. , Воронина Татьяна Александровна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Изучение особенностей кардиопротекторного действия триметазидина и афобазола у крыс с алкогольной кардиомиопатией
Authors: Мирошкина Ирина Александровна , Ионова Екатерина Олеговна , Цорин Иосиф Борисович , Столярук Валерий Николаевич , Вититнова Марина Борисовна , Сорокина Александра Валериановна , Крыжановский Сергей Александрович , Дурнев Андрей Дмитриевич
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Пептидный анксиолитик селанк препятствует этанол-индуцированному повышению BDNF в префронтальной коре и гиппокампе крыс в условиях алкогольной абстиненции
Authors: Антипова Татьяна Алексеевна , Круглов Сергей Васильевич , Надорова Анна Владимировна , Колик Лариса Геннадьевна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Сравнительное изучение эффектов потенциального антиконвульсанта ГИЖ-298 и топирамата на содержание нейротрансмиттеров и их метоболитов в структурах мозга в условиях судорог, вызванных максимальным электрошоком
Authors: Наркевич Виктор Борисович , Литвинова Светлана Александровна , Воронина Татьяна Александровна , Кудрин Владимир Сергеевич
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Особенности анксиолитического действия нового анксиолитика, блокатора центральных холецистокининовых рецепторов ГБ-115
Authors: Незнамов Григорий Георгиевич , Дорофеева Ольга Анатольевна , Метлина Марианна Вячеславовна , Сюняков Тимур Сергеевич , Ивашкина Н.Ю.
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Исследование нейропротекторного действия замещенного глипролина-этилового эфира N-фенилацетилглицил-L-пролина ГЗК-111 in vitro
Authors: Николаев С.В. , Колясникова Ксения Николаевна , Антипов Петр Иванович , Золотов Николай Николаевич , Антипова Татьяна Алексеевна
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Валидизация метода цитогенетического анализа в ооцитах мышей
Authors: Плигина Кира Львовна , Кулакова Алла Владимировна , Жанатаев Алий Курманович , Дурнев Андрей Дмитриевич
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Изучение особенностей влияния длительного периодического приема алкоголя на функциональную активность сердца крыс
Authors: Столярук Валерий Николаевич , Вититнова Марина Борисовна , Цорин Иосиф Борисович , Ионова Екатерина Олеговна , Надорова Анна Владимировна , Баронина Н.В. , Колик Лариса Геннадьевна , Крыжановский Сергей Александрович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Связь активности дипептидилпептидазы-IV с терапевтической экспозицией афобазола при тревожных расстройствах: проверка гипотезы
Authors: Сюняков Тимур Сергеевич , Незнамов Григорий Георгиевич , Золотов Николай Николаевич
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Оценка выраженности антидепрессивной активности дипептидного миметика мозгового нейротрофического фактора ГСБ-106 при субхроническом и хроническом введении
Authors: Таллерова Анна Вадимовна , Поварнина Полина Юрьевна , Гудашева Татьяна Александровна , Середенин Сергей Борисович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Разработка лиофилизата для инъекционного применения на основе дипептида ГК-2
Authors: Тишков Сергей Валерьевич , Блынская Евгения Викторовна , Алексеев Константин Викторович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)
Антиаритмическая активность производных адамант-2-иламидов алкиламинокарбоновых кислот
Authors: Турилова Антонина Ивановна , Авдюнина Нина Ивановна , Грушевская Любовь Николаевна , Пятин Борис Михайлович
Published: July 2018

Материалы V съезда фармакологов России «Научные основы поиска и создания новых лекарств» (14-18 мая 2018 года, г. Ярославль)