bluuebunny/crossref_metadata_2025 huggingface dataset:
The AinS autoinducer synthase and LitR master regulator of quorum sensing regulate N-3-hydroxy-decanoyl-homoserine-lactone production and motility in Aliivibrio wodanis 06/09/139
Authors: Maharajan Amudha Deepalakshmi , Hansen Hilde , Willassen Nils Peder
Published: July 2019

Background
Quorum Sensing (QS) is a cell to cell communication system, in which bacteria synthesize and respond to signaling molecules called autoinducers (AI). QS is cell density dependent and known to be involved in regulating virulence, motility and secretion systems to interact with the host or other bacteria. Aliivibrio wodanis is frequently isolated together with Moritella viscosa from the infected Atlantic salmon during outbreaks of the winter ulcer disease. M. viscosa is the main causative agent of the disease while the presence of A. wodanis is still unclear. It is hypothesized that A. wodanis might influence the progression of winter ulcer. The genome of A. wodanis 06/09/139 encodes two autoinducer synthase genes (ainS and luxS) and a master regulator litR. LitR homologs in other aliivibrios have been shown to regulate several phenotypes in a cell density dependent manner. Moreover, a previous study has shown that A. wodanis 06/09/139 produces only one AHL N-3-hydroxy-decanoyl-homoserine-lactone (3OHC10-HSL). Hence, in this work, we have studied the QS system in A. wodanis 06/09/139 by knocking out QS genes ainS and litR. The effects of the deletions were studied with regard to growth, AHL production and motility at different temperatures.
Results
By using HPLC-MS/MS, we found that the deletion of ainS in A. wodanis 06/09/139 resulted in the loss of 3OHC10-HSL production. The 3OHC10-HSL production in A. wodanis 06/09/139 increased with increase in cell density and more 3OHC10-HSL was produced at 6°C than at 12, 16 and 20°C. The litR mutant demonstrated a ~20% reduction in the production of 3OHC10-HSL relative to the wild type at the stationary phase. Compared to the wildtype and the ainS mutant strains, the litR mutant resulted in a strain with improved temperature tolerance. The motility in mutants (∆litR and ∆ainS) were significantly higher than that of the wildtype.
Conclusions
Our study shows that AinS in A. wodanis 06/09/139 is the AHL synthase responsible for 3OHC10-HSL production, where the production is both cell density and temperature dependent. Our data also shows that LitR regulates 3OHC10-HSL production only to a minor extent and both LitR and AinS are negative regulators of motility.
Prepared for PrEP: Preferences for HIV pre-exposure prophylaxis among Chinese men who have sex with men from an online national survey
Authors: Huang Wenting , Wu Dan , Ong Jason O. , Smith M. Kumi , Yang Fan , Fu Hongyun , Tang Weiming , Tucker Joseph D.
Published: July 2019

Pre-exposure prophylaxis (PrEP) is not widely available in China. Previous studies reported low awareness and inconclusive findings on the acceptability of PrEP among Chinese men who have sex with men (MSM). We conducted a secondary analysis of an online national survey comparing the interests and preferences for oral and long-acting injectable PrEP among MSM and their correlates with HIV risk behaviors. Nine-hundred seventy-nine out of 1045 men responded to the PrEP survey questions. Most men had never heard of PrEP (81.9%) but reported interest in using PrEP. More participants chose injectable PrEP (36.3%) as their preferred formulation than oral PrEP (24.6%). Men who had at least two HIV tests (aOR = 1.36, 95%CI 1.04, 1.78) more commonly preferred injectable PrEP. Future PrEP promotion could be introduced along with HIV prevention and testing services through community activities.
Risk factors, antimicrobial susceptibility pattern and patient outcomes of Pseudomonas aeruginosa infection: A matched case-control study
Authors: Alhussain Fatima A , Eidan Fahad A Al , Johani Sameera Al , Badri Motasim
Published: July 2019

Background

Pseudomonas aeruginosa (P.aeruginosa) is a leading nosocomial gram-negative pathogen associated with prolonged hospitalization, morbidity and mortality. Limited data exist regarding P.aeruginosa infection and outcome in patients managed in intensive care units (ICUs). We aimed to determine the risk factors, antimicrobial susceptibility pattern and patient outcomes of P.aeruginosa infection.

Methods

In this matched case-control study, all P.aeruginosa infections that occurred >48 hours after hospital admission between January 31st 2016 and December 31st 2018 at ICUs affiliated with King Abdulaziz Medical City, Riyadh were included. P.aeruginosa bacilli was confirmed using API 20E test and antimicrobial susceptibility using disk diffusion or Epsilometer test.

Results

The study included 90 cases and 90 controls. Compared with controls, cases had significantly higher mean ICU stay days, proportions of patients with previous history of antimicrobial therapy, coronary artery disease, malignancy, hemodialysis, previous surgery, use of central line, urethral catheterization, nasogastric tube, and tracheostomy. In a multivariate conditional logistic regression analysis, factors independently associated with P.aeruginosa infection were ICU duration [Odds Ratio (OR)=9.05,95%CI 2.53-32.27, p=.001], previous surgery (OR=7.33,95%CI 1.66-32.36,p=.009), tracheostomy (OR=11.13,95%CI 1.05-118.59,p=.046), urethral catheterization (OR=7.38,95%CI 1.21-45.11,p=.030) and aminoglycoside drug class (OR=10.59,95%CI 1.14-98.13,p=.038). Of antimicrobial drugs used, highest proportion of resistance was calculated for patients receiving tigecycline (93.3%). Mortality was high in both groups but did not differ significantly: 54(60%) cases and 51(56.7%) controls; p=.650.

Conclusions:
The study identifies several modifiable factors associated with P.aeruginosa infection in ICUs. These factors are of paramount relevance for case identification, control measures, and optimal treatment strategies of P.aeruginosa infection in ICUs.
What do teachers and leaders have to say about co-teaching in flexible learning spaces?
Authors: Mackey Julie , O’Reilly Neill , Fletcher Jo , Jansen Chris
Published: July 2019

Schools in New Zealand and parts of Australia are rapidly transitioning from traditional classrooms to coteaching in flexible learning spaces provisioned for 50 to 180 children and two to six teachers in a single space. In New Zealand, this transition is driven by the Ministry of Education who have specific guidelines for designing new schools and re-builds. School leaders and teachers must reconceptualise teaching and learning from private autonomous learning environments to co-teaching in shared learning spaces.

This mixed methods study examined the views of 40 practitioners and leaders, experienced in coteaching contexts in New Zealand and Australian schools, to develop a greater understanding of the factors that contribute to effective co-teaching implementation. Not surprisingly, educators highlighted that shared beliefs about student centred pedagogy were pivotal to their co-teaching relationships. Beyond this central element, participants also identified a range of systems, tools, strategies and skills that enabled co-teaching to focus on and support student learning. The study provides insights of value to school leaders who are faced with the challenges of implementing flexible learning spaces, and leading school change in this area.
Widening the leadership story – moving beyond the individual
Authors: Baxendine Linda
Published: July 2019

Distributed leadership that includes democratic practices can open spaces for children and their families to share their knowledge and skills and participate in everyday early childhood leadership activity. Drawing on the findings of a Masters thesis this article discusses how one kindergarten’s exploration of the local community has afforded insights into reframing leadership as an emerging social process whereby teachers, children and families are participants in an approach to leadership described as democratic leadership. Past leadership research has commonly focused on skills, traits and behaviours of people deemed leaders. Moving away from the primacy of the individual towards knowing leadership as an emergent phenomenon that exists between people incorporating multiple worldviews, elevates democratic principles such as collaboration and meaningful participation. Leadership-as-practice was used to analyse the ways in which excursions into the community have broadened teachers’ understandings of leadership and fostered more democratic and inclusive participation of children and families in the kindergarten programme. Utilising excursions within the local community as a mechanism to support a democratic form of leadership suggests that leadership can be perceived as arising from the collective work of people in everyday contexts. The value of extending the learning environment beyond the boundaries of the kindergarten, to engage with the local community, offers possibilities to make connections with the surrounding land, understand local stories, histories and cultural events. In this sense democratic leadership intersects with place-based education as children’s awareness of themselves as citizens of a community deepens. Inquiry as a form of participatory democracy was a key feature of decision-making in this study and provided a common purpose for community excursions while encouraging leadership opportunities.
Middle-level leaders as direct instructional leaders in New Zealand schools: A study of role expectations and performance confidence
Authors: Cardno Carol , Robson Joanne , Bassett Martin , Howse Jo
Published: July 2019

The literature on instructional leadership consistently assigns this role to school principals whilst indicating that it can be spread amongst others. Recently the spotlight has moved to middle leadership involving a focus on classrooms through direct instructional leadership. The purpose of this study was to add to a small but growing body of literature that centres on middle-level leadership in schools. The research aims were to conceptualise the nature of the direct form of instructional leadership that has been devolved to the middle leadership level; investigate perceptions of expectations held of middle leaders in schools; and investigate their perceived confidence in performing the role. An on-line survey of 185 primary and secondary school middle-level leaders confirmed strong agreement with the role expectations described in terms of a conceptual framework of direct instructional leadership. The results indicated that whilst overall confidence in performing these tasks was high, gaps existed between role expectations and performance confidence, with the function of “having difficult conversations” being the largest gap for both primary and secondary school middle-level leaders.
The Others in Charlotte Brontë’s Jane Eyre: A Postcolonial-Orientalist and Feminist Reading
Authors: BARIN AKMAN Filiz
Published: July 2019

There are different forms of

othering in Charlotte Brontë’s Jane Eyre:  one which results from Jane’s ambiguous

position in terms of class hierarchies and another generated by Bertha’s

presence as a colonized subject. In both cases, femininity amplifies gender-specific

repercussions in these othering processes. However, while Brontë creates a

female character in Jane who triumphs over the challenges posed by Victorian

society’s class and gender hierarchies, i.e., the status as other of

governesses and women, problematic as it is in its final solidification of the

status quo, Bertha reflects the dominant, Eurocentric ideologies of nineteenth

century England concerning race and the racial other. She is the colonized and

racial other, a madwoman who threatens British men as embodied in Mr.

Rochester, and women embodied as in Jane, and her final self-destruction for

Jane’s sake are poignant plot devices to this end.  This paper offers a comparative reading of

two female characters’ othered status in Victorian British society in relation

to the dominant ideologies of the era concerning gender, class and race. I

argue that whereas Brontë, following a feminist reading of her novel, fictively

assuages the othered status of British women in the characterization of Jane,

who triumphs in resisting society’s rigid class boundaries and women’s

subordinate position in terms of legal and financial matters, does not grant a

similarly fictive emancipatory view to Bertha as the colonized and racial

other. This is an obvious and clear indication of Brontë’s limitations

concerning feminist activism and inclusiveness as her implication in advancing

the dominant, imperialist discourse.
Divan Şiirinde “Dedim-Dedi” Söyleyişi
Authors: TAŞKESENLİOĞLU Lokman
Published: July 2019

Divan edebiyatı, başlangıcından 19. yüzyıla kadar oluşturduğu zengin edebî

gelenek ile gerek halk edebiyatının gerekse Tanzimat döneminden itibaren

yenileşme dönemi Türk edebiyatının şekillenmesine yardımcı olmuştur. Özellikle

halk edebiyatını nazım birimi, nazım şekilleri, mazmunlar ve ölçü gibi

hususlarda etkilemiş, pek çok halk şairi bu bakımdan divan edebiyatından

beslenmişlerdir. Bu etki ters istikamette de hâsıl olmuş, belli başlı

hususlarda divan şairleri de millî şiir geleneğinden etkilenmiş, halk

edebiyatının karakteristik özelliklerinden faydalanmışlardır. Bazı divan

şairlerinin hece ölçüsünü kullanmaları, türkü gibi nazım şekillerinin

örneklerini vermeleri, dilde sadeleşme temayülleri bu müşterek noktalar

arasında gösterilebilir. Klasik şairlerin halk şiirinden etkilenerek

eserlerinde kullandıkları bir diğer üslup özelliği de “dedim-dedi” veya

“mürâcaa” olarak ifade edilen söyleyiş tarzıdır. Erzurumlu Emrah, Âşık Ömer,

Gevheri gibi pek çok halk âşığının sevgili ile karşılıklı konuşuluyormuş

edasıyla söyledikleri şiirler ile geleneğe kattıkları bu samimi söyleyişin

örneklerini divan edebiyatında da görmek mümkündür. Bu söyleyiş bazen

beyitlerde sınırlı kalmış, bazen de tıpkı halk şiiri örneklerinde olduğu gibi

şiirin tamamına hâkim olmuştur. Fuzûlî, Ahmedî, Şeyhî, Muhibbî gibi pek çok

önemli divan şairinin dahi şiirlerinde bu söyleyişe yer vermeleri, divan ve

halk edebiyatları arasındaki çizginin çok da keskin olmadığını, divan

şairlerinin halktan ve halk şiirinden kopuk bir şiir anlayışı

geliştirmediklerini göstermektedir. Bu çalışmada halk şiiri üslup

özelliklerinden olan “dedim-dedi” söyleyiş tarzının divan edebiyatındaki

yansıması ele alınmıştır. Halk edebiyatından örneklerle birlikte mürâcaa

söyleyişi hakkında verilen genel bilginin akabinde beyit ve şiir bütünlüğü

çerçevesinde bu söyleyiş özelliği taşıyan metinler verilmiş, bu şekilde

“dedim-dedi” tarzının divan edebiyatındaki örnekleri derlenmiştir.
Liedtexte Der 90er Jahre Mit Migrationshintergrund
Authors: BALCI Umut
Published: July 2019

Die Musik hat dank ihrer

spezifischen, autonomen und wirksamen Sprache eine kommunikative Dimension, die

die Menschen aus verschiedenen Kulturen einander näherbringt und die

Integration in andere Gesellschaften erleichtert. Musik der türkischen

Migranten in Deutschland ist in dem Sinne von großer Relevanz, dass türkische

Migranten ab 60er Jahren mit den Deutschen bzw. mit einer fremden Kultur

konfrontiert sind. Davon ausgehend haben wir in dieser Arbeit darauf

konzentriert, zuerst die Entstehungs- und Entwicklungsprozess der türkischen

Migrantenmusik chronologisch in die Hand zu nehmen, danach die Liedtexte der

90er Jahre nach hermeneutischer Methode inhaltlich zu analysieren. Ziel unserer

Arbeit ist es, musikalische Bewegungen türkischer

Migranten in Deutschland bekannt zu machen und somit festzustellen, in welche

Richtung und aus welchen Gründen die Migrantenmusik der 90er Jahre thematisch

entwickelt hat.
Effectiveness of financial and economic regulation of land relations in ukraine in the context of the decentralization reform
Authors: Vatamanyuk-Zelinska Uliana , Sytnyk Nataliia
Published: July 2019

The sphere of local self-governance in Ukraine deals with a need for thorough researching and solving problems concerned with enhancing the effectiveness of financial and economic regulation of land relations on account of the expansion of the decentralization reform. The decentralization has led to gaining additional powers by bodies of local self-government. These powers entitles bodies of local self-government to ensure the increase of local budgets of newly-formed territorial units –united territorial communities – owing to carrying out financial transactions with land plots owned by local communities. In the process of research, the authors determine financial and economic efficiency of revenues of local budgets of perspective territorial communities by each region of Ukraine, taking into account variants of the normative monetary evaluation of land and the standard of capitalized rental income of agricultural lands located beyond their built-up areas. The authors substantiate an opportunity to create budget-forming sources of revenues for local budgets of perspective communities through the exercise of powers of bodies of local self-government regarding indicating the value of such lands and a right to lease, as well as terms of paying a single tax for the use of such lands for agricultural activity by taxpayers belonged to the fourth group of the simplified system of taxation.
Remote Sensing Satellites for Land Applications: A Review
Authors: Kumar Suresh , Bhagat Vijay
Published: July 2019

Satellite remote sensing offers a unique opportunity in deriving various components of land information by integrating with ground based observation. Currently several remote sensing satellites are providing multispectral, hyperspectral and microwave data to cater the need of various land applications. Several old age remote sensing satellites have been updated with new generation satellites offering high spatial, spectral and temporal resolution. Microwave remote sensing data is now available with high spatial resolution and providing land information in cloudy weather condition that strengthening availability of remote sensing data in all days. Spatial resolution has significantly improved over the decades and temporal resolution has improved from months to daily. Indian Remote Sensing programs are providing state of the art satellite data in optical and microwave wavelength regions to meet large land applications in the country. Today several remote sensing data is available as open data sources. Upcoming satellite remote sensing data will help in precise characterization and quantification of land resources to support in sustainable land development planning to meet future challenges.
Müzikal Deşifrenin Boyutları ve Etken Faktörleri
Authors: Öztutgan Kaan , Akbulut Fatih
Published: July 2019

Müzikal
deşifre, zihnin ve bedenin karmaşık işlemler gerçekleştirdiği çok boyutlu bir
süreçtir. Nitel araştırma yönteminin benimsendiği bu çalışmada deşifrenin
boyutları ve deşifreyi etkileyen faktörler sistematik bir şekilde ele
alınmıştır. Bu sayede deşifre konusunun araştırmacı ve öğrencilere daha
bütünlüklü, anlaşılır bir biçimde sunulması hedeflenmiştir.

Literatür
taramasından yararlanılarak hazırlanan bu çalışmada, deşifrenin öğrenme, okuma,
seslendirme olmak üzere üç temel boyutta sınıflandırılabileceği ve bu boyutları
etkileyen tüm faktörlerin deşifreyi de etkilediği sonucuna ulaşılmıştır. Ayrıca
araştırmada elde edilen bulgular ışığında deşifresini geliştirmek isteyen
öğrenci ve müzisyenlere birtakım öneriler sunulmuştur.
Bozüyük Kasım Paşa Camii Süsleme Programı
Authors: Bilir Timur
Published: July 2019

Günümüzde Bilecik’e bağlı bir sanayi kenti
olan Bozüyük, Osmanlı İmparatorluğu’nun kuruluşundan milli mücadele yıllarına
kadar önemli bir tarihi geçmişe sahiptir. Demiryolu hattının açılmasına kadar
kara yolu güzergâhında bulunan ilçe, Osmanlının doğu seferlerine çıkarken
konaklama noktası olarak kullandığı bir merkez konumundaydı. 16. yüzyılın ilk yarısında Kasım
Paşa tarafından buraya yaptırılan külliye, günümüzdeki Bozüyük şehrinin varlık
sebebi olmuştur. Külliyeden günümüze orijinalliğini koruyarak gelen tek yapı
cami kısmıdır. Dışardan sade bir mimarisi olan caminin içinde zengin bir
süsleme programı bulunmaktadır.  Bu
makalede, caminin süslemeleri detaylı bir şekilde ele alınarak süslemelerle
ilgili çizim ve fotoğraflara yer verilmiştir.
Temel Tasarım Eğitiminde Bauhaus Okulu'nun Mekan Üretimine Etkisi
Authors: Hasgül Esin , Birer Emel
Published: July 2019

Bu çalışma mimari tasarım
eğitimine başlarken "Temel Tasarım" aracılığıyla mekan organizasyonunu öğretme
isteği üzerine kurgulanmış, tasarlama deneyimi üzerine Bauhaus etkisinin ele
alınmasını ve bu etkinin oluşturduğu alt açılımların mimari mekan tasarımına ne
şekilde yansıyabileceğinin sorgulanmasını içermektedir. Bu çalışmanın amacı Bauhaus
okulu ilkeleri ile tasarım (mekan organizasyonu) ilkeleri arasındaki ilişkiyi
keşfetmek ve bu ilişkinin yansımalarını mimari tasarım eğitimi üzerinden
değerlendirmektir. Çalışmada yöntem olarak mekanı anlamanın ve yorumlamanın düşünsel sistematiği
analiz-transformasyon(dönüşüm)-sentez süreçleriyle ele alınmakta ve elde
edilen bulgular üzerinden mekan organizasyonu ile Bauhaus çalışmalarının
ilişkisi ortaya çıkarılmaktadır. Bu doğrultuda araştırma kapsamında, "Temel
Tasarım" stüdyosunda tasarıma giriş yapan öğrencilerin Bauhaus okulu etkileri
üzerinden oluşturdukları ürün tasarımları incelenmekte, bu tasarlama sürecinde
sonuç ürünlerin, düşünsel altyapı ile oluşturulan kimlik arasındaki mekânsal
ilişkisi ele alınmaktadır. Sonuç olarak Bauhaus okulu ilkeleri ile tasarım (mekan
organizasyonu) ilkeleri arasındaki ilişkiyi keşfetmek mimari tasarım eğitiminde
önemli bir başlangıçtır.
Mimarlık Kuramlarında Değişen Estetik Yaklaşımları Yeniden Düşünmek
Authors: Kırhallı Tarık Emre , Koçyiğit Rifat Gökhan
Published: July 2019

Bu çalışmada, Antik Dönem’den günümüze
ortaya konmuş estetik odaklı mimarlık kuramları estetik değer yönünden
incelenmiştir. İncelemede, kuramların yazıldıkları mimarlık ortamları ve bu
kuramların yer verdikleri değerler ortaya konmuş, bu sayede de değerlerin
ontolojik (varlıkbilimsel) statülerine ulaşılıp, bu statülerin anlamlandırılıp
sınıflandırılması sağlanmıştır. Bu çerçevede, tarihsel süreçte mimarlığın gittikçe
daha çok ‘bir uzmanlaşma alanı’ haline geldiği ve uygulayıcısı mimar figürüyle birlikte önem
kazandığı görülmüştür. Değer kazanma/değerlendirilme şemalarında ise, mesleki
uzmanlaşma ve ‘özne’nin artan önem ve etkinliğiyle paralellik kurulabilecek şekilde, önce
bir öznelleşme ve akılcılaşma, ardından ise bir önem kaybı ile karşılaşılmıştır.
Bu bağlamda ontolojik anlamda da, birbirinden farklı dört değer statüsüyle karşılaşılmış,
bu değerlerin ontik
statülerindeki değişimlerin mimarlık kuramlarının anlamsal içerikleri açısından
önemi yorumlanmaya çalışılmıştır.
Antenatal Depression and Anxiety Among Women with Threatened Abortion: A Case-Control Study
Authors: Astepe Bahar Sariibrahim , Bosgelmez Sukriye
Published: July 2019

Objective: Threatened abortion is a stressful condition for a pregnant woman which may influence mental health. This study aims to investigate the relationship between threatened abortion, anxiety, and depression during pregnancy. Study Design: Study group consisted of 121 pregnant women <20 weeks of gestation having vaginal bleeding; control group consisted of 129 pregnant women <20 weeks of gestation not having vaginal bleeding in their pregnancy until that time. Hospital anxiety and depression scale was used to assess potential anxiety and depression. Results: Statistical analyses indicated that (i) vaginal bleeding group had significantly higher rates of moderate/ severe anxiety (28.1% vs. 14.7% p=0.010); (ii) there was no statistically significant difference between depression rates of the women according to the presence of vaginal bleeding (38.8% vs. 34.9% p=0.517); (iii) low education (OR=2.233; 95% CI: 1.177-4.236; p=0.014) was possible predictors of antenatal depression. Although in the univariate analyses age, gravidity, and parity were associated with anxiety, only nulliparity was found as possible predictors of anxiety (OR=2.589; 95% CI: 1.362-4.922, p=0.004). Conclusion: Pregnant women without obstetric complications had similar rates of depression and anxiety as in women with threatened abortion, although anxiety levels were higher in women with threatened abortion.
Manoglanistara - Emotional Wellness Phases Prediction of Adolescent Female Students by using Brain Waves
Authors: Mallikarjun H.M. , Manimegalai P.
Published: July 2019

Background:

Depression is the most underestimated and widespread health condition
among people in developing countries. Depression levels among Indian population are rapidly increasing.
It can be attributed to work pressure, social challenges, addiction to social media, adoption
of the western culture and several other reasons. Indians’ depression levels are as high as 36
percent and shockingly this number is the highest in the world.

Objective:

What makes this even more alarming is the fact that WHO projects depression to be the
second leading cause of disability worldwide by2020.

Materials and Methods:

This work focuses on Machine learning based Depression prediction by
utilizing different brain wave frequency bands. It is carried out by askingthe universal standard
Patient Health Questionnaire (PHQ.9) to subjects which are related to respective emotions. Neurosky’s
Mind Wave Head kit is connected to the forehead (of subject) and 86 sample values are
recorded. Total 85 Samples are trained, whereas 1 data is tested.

Results:

The MANOGLANISTARA- android App has been designed which sends the Emotional
Wellness output (depressed/normal) to the subject via email. This provides the basis of analysis as
to whether the subject is suffering from depression or not. Customization of the medication and
treatment to such subjects can be initiated by the doctors.
In this work, the MATLAB SVM based Depression prediction model is developed by evaluating
the data built from Mindwave kit and standard PHQ.9 questionnaire. Work is also extended by using
Orange Toolbox for classification of depressed/ normal subjects.

Conclusion:

In Orange toolbox, Prediction, ROC Analysis and Confusion Matrix are evaluated
for different classifiers such as SVM, Naïve Bayes, Classification tree, Random forest and CN2
Rule Inducer. Accuracy, Precision, Sensitivity and Specificity is computed for all the abovementioned
classifiers. CN2 Rule Inducer classifier gave higher accuracy of 0.9418, sensitivity
0.9778, Specificity 0.9736 and Precision 0.9778.
Implications of Vitamin D in Multiple Sclerosis and Other Neurodegenerative Processes: Bibliometric Analysis and Systematic Review
Authors: Caballero-Villarraso Javier , Jiménez-Jiménez María J. , Escribano Begoña M. , Agüera Eduardo , Santamaría Abel , Túnez Isaac
Published: July 2019

:

In recent years, numerous investigations focused on the pleiotropic actions of vitamin D have been carried out. These actions include the participation of this molecule in neurophysiological and neuropathological processes. As a consequence, abundant scientific literature on the role of this vitamin in neurodegenerative entities has emerged, even concerning clinical studies. To identify the level of scientific evidence concerning the relation between vitamin D and neurodegenerative diseases, from a quantitative and qualitative perspective. To describe, by means of a bibliometric analysis, the scientific production and its evolution through time in quantitative terms, regarding the implications of vitamin D in neurodegeneration. To analyse and present the degree of evidence in the aforementioned field of study, a systematic review of the literature focused on the most prevalent neurodegenerative diseases was carried out. We retrieved 848 articles in the bibliometric analysis, the majority of which were dated between the years 2010-2017. The most studied metabolite was the 25(OH)D3 and the most cited disease was multiple sclerosis. In the systematic review, we found studies about Alzheimer’s and Parkinson’s diseases and again, about multiple sclerosis prominently (in number and quality), with 12 randomised double-blind clinical trials. The research about vitamin D and its relations with neurodegenerative diseases shows a growing evolution over the last decade. More studies are needed to find correlations between the clinical severity of these diseases and the specific status of vitamin D and the genotypes related with them, which seems to be a future trend.
Carbon Dots as Catalysts: A New Class of Nanozymes
Authors: Zammataro Agatino , Sfrazzetto Giuseppe Trusso
Published: July 2019

Carbon Dots (CDs) represent a new class of nanoparticles carbon-based having many application fields. This
perspective summarizes the catalytic applications of CDs with potential future perspectives.
Minat siswa sekolah menengah pertama terhadap pembelajaran atletik
Authors: Utami Maratona Sakti , Purnomo Eddy
Published: July 2019

Penelitian ini dilatarbelakangi oleh belum maksimalnya pembelajaran pendidikan jasmani pada materi atletik dan belum diketahuinya minat siswa terhadap pembelajaran atletik. Penelitian ini bertujuan untuk mengetahui minat siswa kelas VIII SMP Negeri 2 Jenawi Kabupaten Karanganyar dalam mengikuti pembelajaran atletik. Penelitian ini merupakan penelitian dekriptif kuantitatif. Metode yang digunakan adalah metode survei dengan teknik pengumpulan data menggunakan angket. Subjek penelitian ini adalah seluruh siswa kelas VIII kecuali kelas VIII C karena dijadikan sebagai uji coba penelitian, dari 4 kelas dipilih 25 siswa dengan cara diundi, sehingga mendapatkan populasi sebanyak 100 siswa. Teknik analisis yang dilakukan adalah menuangkan frekuensi ke dalam bentuk persentase. Hasil penelitian ini menunjukkan bahwa minat siswa SMP Negeri 2 Jenawi Kabupaten Karanganyar kelas VIII terhadap pembelajaran atletik adalah cukup. Dengan pertimbangan frekuensi terbanyak berada pada kategori sedang dengan persentase 83,00%. Persentase minat siswa SMP Negeri 2 Jenawi Kabupaten Karanganyar kelas VIII terhadap pembelajaran atletik yang berkategori sangat tinggi adalah 0,00%, tinggi 11,00%, sedang 83,00%, kurang 6,00% dan sangat kurang 0,00%. Interest of students of class VIII junior high school on athletic learning Abstract.The background problem of this research because not maximal yet in physical education learning on athletic material and the students' interest in athletic learning was unknown yet. This research aimed to know the students’ interest in athletic learning at the eighth-grade students of SMP 2 Jenawi Karanganyar regency. This research was quantitative descriptive research. The method used in this research was survey method while the technique of collecting the data used questionnaire. The research subject was the whole of eighth-grade students except VIII C class because it was used as a research trial, from four classes was chosen 25 students randomly, it got a population of 100 students. The technique of analyzing the data used the frequency in the form of the percentage. The result of the research showed that students’ interest in athletic learning at the eighth-grade students of SMP Negeri 2 Jenawi Karanganyar regency was enough. With consideration of the most frequency was enough with the percentage 83%. The percentage of students’ interest in athletic learning at the eighth-grade students of SMP Negeri 2 Jenawi Karanganyar regency who had the highest category was 0,00%, high 11,00%, enough 83%, low 6,00% and the lowest was 0,00%.
Maria de Magdala:
Authors: Bacarin Adriane Viola
Published: July 2019

Este trabalho relaciona a passagem de Maria de Magdala no Novo Testamento, ao despertar do si-mesmo, após vivenciar estágios egoicos dolorosos e o resgate do feminino na visão da psicologia analítica. Para tanto, foram delimitados os seguintes conceitos: o feminino e a misoginia; anima eanimus; aspectos da sombra; e, por fim, a função transcendente. Foi possível descrever os momentos da história pessoal da personagem, alguns aspectos históricos, o modo como vivia o povo de Magdala, a cultura, as leis, os costumes e a interpretação dos símbolos que a passagem traz. Identificaram-se alguns arquétipos relacionados ao comportamento da mulher e a projeção social que perdura ainda hoje, bem como os aspectos daanima e animus e a projeção desses opostos, representados pela violência e discriminação contra a mulher. Identifica-se, desse modo, que o encontro da personalidade Maria com Jesus (representação do Self), permitiu que refizesse sua trajetória e concluir que a direção das atitudes da personagem a partir do encontro com Jesus e o resgate do feminino, a transformou para sempre, servindo-nos como um grande exemplo de lapidação do si-mesmo que visa o despertar da Grande Personalidade dentro de cada um de nós.
Common Data Elements for Acute Coronary Syndrome: Analysis Based on the Unified Medical Language System
Authors: Kentgen Markus , Varghese Julian , Samol Alexander , Waltenberger Johannes , Dugas Martin
Published: July 2019

Background

Standardization in clinical documentation can increase efficiency and can save time and resources.

Objective

The objectives of this work are to compare documentation forms for acute coronary syndrome (ACS), check for standardization, and generate a list of the most common data elements using semantic form annotation with the Unified Medical Language System (UMLS).

Methods

Forms from registries, studies, risk scores, quality assurance, official guidelines, and routine documentation from four hospitals in Germany were semantically annotated using UMLS. This allowed for automatic comparison of concept frequencies and the generation of a list of the most common concepts.

Results

A total of 3710 forms items from 86 sources were semantically annotated using 842 unique UMLS concepts. Half of all medical concept occurrences were covered by 60 unique concepts, which suggests the existence of a core dataset of relevant concepts. Overlap percentages between forms were relatively low, hinting at inconsistent documentation structures and lack of standardization.

Conclusions

This analysis shows a lack of standardized and semantically enriched documentation for patients with ACS. Efforts made by official institutions like the European Society for Cardiology have not yet been fully implemented. Utilizing a standardized and annotated core dataset of the most important data concepts could make export and automatic reuse of data easier. The generated list of common data elements is an exemplary implementation suggestion of the concepts to use in a standardized approach.
Preventing Emerging and Re-emerging Infections in the Eastern Mediterranean Region: Gaps, Challenges, and Priorities
Authors: Araj Rawan , Alqasrawi Sultan , Samy Sahar , Alwahdanee Ghaya , Wadi Jamal , Mofleh Jawad , Alsanouri Tarek
Published: July 2019

Background

The Eastern Mediterranean Public Health Network, supported by the Biosecurity Engagement Program, contributed significantly to strengthening the preparedness and response to the emerging and re-emerging infections in the region.

Objective

This study aimed to determine the gaps, challenges, and priorities for preventing the emerging and re-emerging infections, with a focus on biosafety and biosecurity in four countries of the region, namely, Egypt, Iraq, Jordan, and Morocco.

Methods

A total of two different methods were used to determine the gaps and priorities for preventing the emerging and re-emerging infections. The first method was a rapid assessment for the preparedness and response to the emerging and re-emerging infections in four countries of the region, with a focus on biosafety and biosecurity. The second method was a face-to-face round table meeting of the participating teams for two days, where the teams from all countries presented their countries’ profiles, findings, priorities, and gaps based on the countries’ assessments.

Results

The assessment and meeting resulted in several priorities and recommendations for each of the countries in the areas of legislation and coordination, biosafety and biosecurity, surveillance and human resources, case management and response, infection control and prevention, and risk communication and laboratory capacity.

Conclusions

Many recommendations were relatively consistent throughout, including improving communication or building collaborations to improve the overall health of the country.
E-portfolio, a useful tool for reflection and feedback (Preprint)
Authors: Rezaee Rita , Zarifsanaiey Nahid
Published: July 2019

UNSTRUCTURED

Utilizing an electronic portfolio (e-portfolio) is an effective means of enhancing the learning experience in educational settings. In the present study an e-portfolio framework was designed for medical education at Shiraz University of Medical Sciences. The objective was to assess learning progress in a medical course that provides instructor feedback via e-portfolio and promotes self-reflection among the students. The results indicate that using e-portfolio stimulates self-reflection in students and increases their active participation in the learning process. Integrating e-portfolios in educational programs can remarkably improve the academic performance in the fields of medicine and healthcare.
The Use of Smartphone-Based Triage to Reduce the Rate of Outpatient Error Registration: Cross-Sectional Study (Preprint)
Authors: Xie Wanhua , Cao Xiaojun , Dong Hongwei , Liu Yu
Published: July 2019

BACKGROUND

In many clinics, patients now have the option to make Web-based appointments but doing so according to their own judgment may lead to wrong registration and delayed medical services. We hypothesized that smartphone-based triage in outpatient services is superior to Web-based self-appointment registration guided by the medical staff.

OBJECTIVE

This study aimed to investigate smartphone-based triage in outpatient services compared with Web-based self-appointment registration and to provide a reference for improving outpatient care under appointment registration.

METHODS

The following parameters in Guangzhou Women and Children’s Medical Center were analyzed: wrong registration rate, the degree of patient satisfaction, outpatient visits 6 months before and after smartphone-based triage, queries after smartphone-based triage, number of successful registrations, inquiry content, and top 10 recommended diseases and top 10 recommended departments after queries.

RESULTS

Smartphone-based triage showed significant effects on average daily queries, which accounted for 16.15% (1956/12,112) to 29.46% (3643/12,366) of daily outpatient visits. The average daily successful registration after queries accounted for 56.14% (1101/1961) to 60.92% (1437/2359) of daily queries and 9.33% (1130/12,112) to 16.83% (2081/12,366) of daily outpatient visits. The wrong registration rate after smartphone-based triage was reduced from 0.68% (12,810/1,895,829) to 0.12% (2379/2,017,921) (P<.001), and the degree of patient satisfaction was improved. Monthly outpatient visits were increased by 0.98% (3192/325,710) to 13.09% (42,939/328,032) compared with the same period the preceding year (P=.02).

CONCLUSIONS

Smartphone-based triage significantly reduces the wrong registration rate caused by patient Web-based appointment registration and improves the degree of patient satisfaction. Thus, it is worth promoting.
Preliminary Study of Total Suspended Solid Distribution in Coastal Ujung Pangkah Gresik Based Reflectance Value of Landsat Satellite Imagery
Authors: Wibisana Hendrata , Soekotjo Bangun Muljo , Lasminto Umboro
Published: July 2019

Total suspended solid (TSS) is one of the parameters that uses for detecting health in aquatic environments. The distribution of the TSS value in the water body will affect the aquatic ecosystem. In this research will be analyzed the distribution value of TSS during 5 year period by utilizing Landsat 8 satellite image data, where the developed method is extraction of reflectance value from Landsat 8 satellite image for 5 years using SEADASS and then compiled the TSS algorithm with reflectance value that already obtained on the existing conditions, the algorithm obtained is estimated over 5 years back to get a picture of change and distribution of TSS value. As a case study , the coast of Ujung Pangkah Gresik was taken which has the mouth of the river Bengawan Solo. The results obtained from this study illustrate the decrease of TSS value during that time period, so that with this decrease can be concluded that at the point of field coordinate, TSS value was decreasing and causing the erosion in the environment.
Analisis Budaya Keamanan Informasi di Puskesmas Kota Bandung
Authors: Syauqina Syaza , Sari Puspita Kencana , Prasetio Adhi , Candiwan Candiwan
Published: July 2019

Background : The use of information systems today has become a necessity in organizations, including in the health sector due to the large amount of patient data that must be managed. 95% of Bandung City citizens are entitled to health facility services in all health facilities that have been partnered with BPJS Kesehatan, one of which is the Puskesmas. In its service, the Puskesmas manages patient health data using computer-based SIM Puskesmas, thus personal health information is vulnerable to information security threats both from internal and external. Therefore, Puskesmas need to build information security to reduce the level of security violations and maintain the health information of their patients.Objective : The purpose of this study was to determine the factors that significantly influence the Culture of Information Security in Bandung Public Health Center.Methods : The research method used is a quantitative method with PLS-SEM data analysis technique using WarpPLS 6.0 software. The technique used is Model Evaluation consisting of Measurement Models, Structural Models and Hypothesis Testing. This research data uses primary data taken through questionnaires to 154 employees who were sampledResults : Based on the characteristics of the respondents it can be seen that the majority of health center employees are women, the highest age is 19-29 years, the most positions are Administration / Medical Records, Education of employees is S1, lenght of work of Employees is 1-5 years. In the information management process, the Puskesmas has used Computer Based. The Puskesmas has an Information Security Policy. Based on the Evaluation Model, it can be seen that the model is fit, because it meets the Rule of Thumb criteria.Conclusion : Based on the results of the Model Evaluation and Hypothesis Testing, it can be seen that the variables that influence the Information Security Culture in Bandung City Health Center are Management, Change Management, Knowledge, Soft Issue-Workplace Independent and Attitude.Keywords :  Information Security Culture, Healthcare, PLS-SEM.
Ketahanan Umat Beragama Dalam Mencegah Radikalisme di Kota Mataram Nusa Tenggara Barat
Authors: Muhtar Fathur Rahman , Jihad Salimul
Published: July 2019

ABSTRACTThis study aimed to determined the resilience of religious people in preventing the occurrence of radicalism in the city of Mataram. This research used indept interview method, field observation, and documentation, while data analysis usedgrounded theory design, that was expressing the experience of the people involved and knowing the problem being studied. This results of this study indicated that the form of cooperation between religious communities in the city of Mataram ran naturally, without any forms of cooperation based on written rules among religious followers. Collaboration based on human values   and traditional customs among Hindus, Muslims and Christians. Collaboration with each other helping other religious people in various religious activities was a call and obligation that had been taught by their respective religions. There was an awareness that religion in the theological domain recognizes the existence of the One God, although the expression of religious people was different in defining the form of God in their midst. These forms of natural cooperation could prevent the emergence of religious radicalism in the city of Mataram.ABSTRAKPenelitian ini bertujuan untuk mengetahui ketahanan umat beragama dalam mencegah terjadinya radikalisme di Kota Mataram. Penelitian ini menggunakan metode indept interview, observasi lapangan, dan dokumentasi, sedang analisis data menggunakan desainGrounded Theory, yaitu mengungkapkan pengalaman orang-orang yang terlibat dan mengetahui suatu masalah yang diteliti. Hasil dari penelitian ini menunjukkan  bahwa bentuk kerjasama antar umat beragama di Kota Mataram berjalan secara natural, tanpa adanya bentuk-bentuk kerjasama yang didasari oleh aturan-aturan tertulis antar pemeluk agama. Kerjasama yang didasari oleh nilai-nilai kemanusiaan dan adat istiadat turun temurun antar pemeluk agama Hindu, Islam, dan Kristen. Kerjasama saling membantu umat agama lain dalam berbagai kegiatan keagamaan merupakan panggilan dan kewajiban yang telah diajarkan oleh agama masing-masing. Adanya kesadaran bahwa agama dalam ranah teologis mengakui adanya Tuhan Yang Esa, walaupun ekspresi umat beragama berbeda-beda dalam mendefinisikan wujud Tuhan yang berada ditengah-tengah mereka. Bentuk-bentuk kerjasama yang bersifat natural tersebut dapat mencegah munculnya radikalisme agama di Kota Mataram.
The Right to a Fair Trial before The European Court of Human Rights
Authors: Ismail Abdrabo Alaa Mohamed
Published: July 2019

Article 6 of the European Convention on Human Rights (ECHR) guarantees the right to a fair trial, applies to disputes relating to civil rights and obligations as well as to criminal charges. The right to a fair trial includes, inter alia, the right of access to a court, the right to be heard and the equality of arms between the parties. This challenging new work elucidates the meaning of the fair trial and looks at the fair trials jurisprudence of the ECHR.Article 6 of the European Convention on Human Rights has become the defining standard within Europe for determining the fairness of criminal proceedings. Its success has been attributed to the fact that it is not based on a particular model of criminal procedure.
A Cultural Immersion Experience to Enhance Nursing Students’ Appreciation and Understanding of Different Cultures
Authors: Mitchell, DHEd, MSN, RN Abigail , Jozwiak-Shields, PhD, ANP-BC, RN Connie
Published: July 2019

The practice of studying abroad for professional development is not new and has been undertaken by scholars since the medieval times, however it is a relatively new endeavor in nursing education. Research has shown that cultural knowledge in nursing is extremely important and the lack of it may cause deficits in practice. The purpose of this study is a two-fold. Nursing faculty completed a literature review and sent out a self-designed 15-question survey to all nursing students registered for the travel abroad experience. This experience took place during March 14-24, 2019. The goal of this experience was professional growth and to be more culturally aware in various populations.