bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of novel COVID-19 initial pandemic on orthopedic healthcare: an experience from a single institution of South Korea
Authors: Lee Gun Woo , Kim Gi Beom , Lee In Jun
Published: November 2021

Background: This study was to investigate the cancellation rate and trend of orthopedic surgeries during the novel coronavirus disease 2019 (COVID-19) pandemic. Moreover, we assessed the psychologic status of orthopedic healthcare workers, and investigated the details of the preventive surgeries underwent in COVID-19-positive patients.Methods: For 3 months after January 20, 2020, cancellation rates of elective surgeries were investigated, and the number of elective surgeries conducted in the same period over the last two years was compared. Four different questionnaires were used to investigate psychologic status among the orthopedic health care workers. We compared the outcomes according to occupation (physician or nurse), and type of work (faculty staff or resident physician). Outcomes according to occupation and type of work were compared. Preventive surgeries underwent in patients who could not wait for the results of the COVID-19 diagnosis were investigated.Results: Spine and hip surgery had relatively lower cancellation rates, and elective surgeries were significantly reduced. During the initial pandemic, the cancellation rate of orthopedic elective surgeries was significantly higher than in the same period of the previous year and was different for each subdivision depending on the degree of pain or disability. The psychological outcomes were within the normal range and there were no significant differences between groups. After preventive surgery, all medical staff involved in the operation tested negative.Conclusion: During the COVID-19 pandemic, the cancellation rate of orthopedic elective surgeries was significantly higher than in the same period of the previous year. Orthopedic health care workers did not seem to have significant psychological distress. As a result of the preventive surgery in specialized facilities, all the medical staff who participated in the operation tested negative.
Qual comunidade construir? Belisário, um distrito na mira de uma grande mineradora
Authors: Dias Gabriel Max de Oliveira , Gomes Ivair , Ferreira Arlon Cândido , Vallejo Luiz Renato
Published: November 2021

Este trabalho tem como tema a possibilidade de início da atividade mineradora no distrito de Belisário/Muriaé-MG. A mineração já é uma realidade em outros municípios da região, sendo realizada pela Companhia Brasileira de Alumínio. A partir de 2016 o atrito entre a empresa e a comunidade se acirrou, pois cresceu no distrito um movimento contrário ao empreendimento. Muitos moradores defenderam que o projeto impactaria negativamente a realidade do distrito, principalmente no tocante a agricultura familiar, ao turismo e a preservação ambiental. A mobilização comunitária obteve a atenção e o apoio externo, resultando em visibilidade que conseguiu transformar o distrito em Patrimônio Hídrico Municipal no ano de 2018. O fato se constituiu numa estratégia para impedir o começo da atividade minerária. Este trabalho buscou compreender a visão dos mais jovens sobre os acontecimentos na comunidade e foi focado nos alunos do 1º e 2º ano do Ensino Médio da escola localizada na sedo do distrito, relacionamento suas expectativas de vida com o projeto de território que eles visam construir e a visão que eles possuem sobre o lugar. Ao final, constatou-se que, para estes jovens, a mineração é uma ameaça sendo mais viável que a comunidade siga suas potencialidades vigentes.
Educação ambiental para o ensino de solos em Geografia: uma proposta aplicada no ensino fundamental e médio em Curitiba (Paraná)
Authors: Da Fonseca Murilo Noli , Da Silva Maria Consuelo
Published: November 2021

Este trabalho tem como objetivo a proposição de uma prática pedagógica para Educação Ambiental de solos em Geografia, levando em conta o espaço socioambiental em que o aluno está inserido. A pesquisa foi aplicada na Escola Hasdrubal Bellegard em Curitiba, Paraná, por meio de aulas teóricas, práticas e produto final. Observou-se que os alunos não compreendiam a dimensão dos conceitos de degradação do solo. A importância da conservação da cobertura vegetal se mostrou mais clara aos estudantes no decorrer das aulas. Na análise dos mapas mentais, os alunos identificaram pouquíssimas áreas ainda preservadas em seu bairro. Estudar, conhecer e entender o solo é uma necessidade real, assim como fazer o aluno perceber na geografia elementos e saberes que tratam da sua realidade e apropriar-se deles.
O encontro entre Geografia e Educação pode mudar o espaço vivido?
Authors: Manfio Vanessa
Published: November 2021

A Geografia em parceria da educação fornece subsídios para os estudantes aprenderem o seu espaço de vida, por meio de práticas e teorias que ajudam o pensamento crítico, a práxis e a transformação socioespacial. Por isso, é importante trazer à tona essa abordagem para se desenvolver caminhos de uma educação voltada para vida. Esta pesquisa bibliográfica centra-se no objetivo de analisar e discutir a interconexão das duas disciplinas como articuladoras da mudança local, dialogando sobre a pedagogia dos projetos e do trabalho de campo para o ensino. Para pensar uma educação mais rica e interessante que contextualiza o espaço é fundamental no campo escolar, já que o espaço é o chão de aprendizados desde a infância da criança até a sua formação total e permite a criação de um sujeito crítico e humano.
O ensino de conceitos geográficos: relatos de práticas em sala de aula
Authors: Cabral Bragelone Jane Claudia
Published: November 2021

O presente artigo é fruto da pesquisa e observação da aula de alguns professores de Geografia que atuam na rede estadual de ensino, na cidade de Natal (RN). Buscamos analisar como os professores ensinam os conceitos geográficos em sala de aula. Para isso observamos as aulas de quatro professores em turmas diferentes, e concluímos que cada um ao seu modo faz a mediação do conteúdo para construir o entendimento de conceitos. Observamos que os conceitos não são entendidos isoladamente, mas dentro do contexto de determinados temas geográficos, em que a mediação entre o professor e o aluno é fundamental para a construção do saber conceitual, essencial para interpretar situações da realidade.
A BNCC, a redução da carga horária de Geografia e o dilema da seleção dos conteúdos: um debate necessário
Authors: Gomes da Silva Matheus , Souza de Santana Sandra , Souza Silva Cristina , Braga Maria Cleonice Barbosa , Morais Queiroz Maria da Conceição
Published: November 2021

O debate que iniciamos neste ensaio tem como principal foco a reflexão sobre algumas perspectivas norteadoras para a presença da Geografia no currículo da escola básica, ao tempo em que sinaliza alguns parâmetros de orientação para a escolha dos conteúdos desse componente frente a reduzida carga horária que se apresenta no Documento Orientador do Ensino Médio baiano (BAHIA, 2000). A análise está ancorada nas diversas experiências dos autores como docentes dessa etapa do ensino, bem como nos escritos de alguns teóricos como Oliveira (2003), Cavalcanti (2011, 2019) Girotto (2017), Giordani (2019), dentre outros. Nessa perspectiva elegeu-se: possibilitar a emergência de uma consciência ambiental; promover comportamento de justiça social e enfrentamento das desigualdades socioespaciais; e considerar os movimentos geopolíticos nas suas diversas escalas como demarcadores de espacialidades/ territorialidades, como sentidos gerais que precisam nortear o ensino dos conteúdos de Geografia a fim de que a mesma não perca totalmente a sua função maior na formação dos jovens.
OBSTACLES TO THE EMPLOYMENT OF THE PERSONS WITH DISABILITIES
FROM THE EMPLOYER'S PERSPECTIVE
Authors: Paušić Vesna , Krstić Tatjana , Vidojević Jelena
Published: November 2021

The role of employers in obtaining a job for people with disabilities can be crucial. The law
on “Professional rehabilitation and employment of people with disabilities” was supposed to
be a key factor in improving the position of this population in the labor market, but in
practice this has not been confirmed. One of the major obstacles to the employment of
persons with disabilities is the lack of a register of persons with disabilities where employers
colud find potential candidates with appropriate skills and competencies. This research was
conducted with the aim of identifying potential barriers to employment of persons with
disabilities perceived from the perspective of employers. The sample consisted of 50
employers of both state and private companies in the city of Novi Sad. Employers were
surveyed with a questionnaire created for the purposes of this research, modeled on the
Employers' Motivation Questionnaire for Employment of Persons with Disabilities with the
prior consent of the author. The results schow that the adaptation of the workplace and access
to means of transport are the biggest obstacle when we are talking about employing people
with disabilities. In order to gain a deeper insight into the perspective of employers regarding
the employment of people with disabilities, it is important to take into account their direct
experiences as well as what worries them and what they feel insufficiently competent when it
comes to employing this population.
Key words: people with disabilities, employers, barriers.
THE ROLE OF KINDERGARTEN IN THE FUNCTION OF PREPARING CHILDREN FOR STARTING SCHOOL
Authors: Tajar Škaljo Mejrima
Published: November 2021

The partnership between kindergarten and family has a special function and importance in the
upbringing and education of the child. The content of the topic refers to the introductory part,
which explains what we will be researching. The partnership between family and
kindergarten has a special significance and role in the function of preparing children for
school. Numerous definitions of family are mentioned in the literature, but given the diversity
of structure, relationships, functions, ways of formation, there are many combinations and it
could be said that each family is unique or a separate definition should be made for each
family. The child is the center of attention in the partnership. The results show that parents
are involved in kindergarten activities, and that they are available for cooperation. This is the
first prerequisite for establishing, above all, quality communication, and thus cooperation. All
parents are interested in the progress of their child and want to cooperate with the
kindergarten in this area. This research is of a theoretical-empirical character. We used
specifically descriptive statistics, which have special significance. The educational
preparation of a child refers to what we call the formation of work habits of learning, on the
one hand, and the acquisition of prior knowledge, on the other. Kindergarten children do not
read or write, make figurines, play, draw, learn numbers up to ten. Educators need to
continuously learn and establish a partnership with the family and the child, in order for the
child to feel accepted, satisfied, happy and successful. It is certainly evident, through our
theoretical research, that we can conclude that educators need to be specially educated to
work with the population of preschool children with a special “dose” of sensibility.
Key words: child, kindergarten, family.
Impaired heart rate recovery may predict radial artery spasm in patients undergoing coronary angiography via radial access
Authors: Gürbak İsmail , Güler Arda , Panç Cafer , Güner Ahmet , Ertürk Mehmet
Published: November 2021

Objectives: Radial artery spasm (RAS) is associated with several pathophysiological pathways, including endothelial and autonomic dysfunction, and causes failed coronary interventions. Heart rate recovery (HRR) is a simple measurement of autonomic nervous system dysfunction. We aimed to investigate the relationship between HRR and RAS during coronary angiography (CA) in the present study.

Patients and Methods: This study included 167 patients (mean age 54.6 ± 8.2, 131 males) who underwent a treadmill stress test (TST) according to the Bruce protocol before trans-radial CA. HRR in the first minute (HRR1) was calculated as the difference between peak heart rate and heart rate one minute after the TST. Patients were divided into two groups according to the presence of RAS.

Results: Among the study population, RAS developed in 26 patients (15.5%). HRR1 and HRR in the third minute (HRR3) were lower in the RAS group. Also, the abnormal HRR1 rate was higher in the RAS group (35.5% vs. 76.9%, p < 0.001). Total procedural time, more than one puncture attempt, more than one catheter use, fluoroscopy time, radiation exposure, contrast volume was higher in the RAS group. Female gender, total procedural time, more than one catheter use, and abnormal HRR1 were independent predictors of RAS.

Conclusion: The current data suggest that a significant relationship was found between abnormal HRR1 and RAS. HRR, a simple autonomic dysfunction parameter, can provide additional information regarding the success of radial procedures.
Combined linear regression and Monte Carlo approach to modelling exposure age depth profiles
Authors: Wang Yiran , Oskin Michael E.
Published: November 2021

Abstract. We introduce a set of methods for analyzing cosmogenic-nuclide depth profiles that formally integrates surface erosion and muogenic production, while retaining the advantages of the linear inversion. For surfaces with erosion, we present solutions for both erosion rate and total eroded thickness, each with their own advantages. For practical applications, erosion must be constrained from external information, such as soil-profile analysis. By combining linear inversion with Monte Carlo simulation of error propagation, our method jointly assesses uncertainty arising from measurement error and erosion constraints. Using example depth profile data sets from the Beida River, northwest China and Lees Ferry, Arizona, we show that our methods robustly produce comparable ages for surfaces with different erosion rates and inheritance. Through hypothetical examples, we further show that both the erosion rate and eroded-thickness approaches produce reasonable age estimates so long as the total erosion less than twice the nucleon attenuation length. Overall, lack of precise constraints for erosion rate tends to be the largest contributor of age uncertainty, compared to the error from omitting muogenic production or radioactive decay.
B-flood 1.0: an open-source Saint-Venant model for flash-flood simulation using adaptive refinement
Authors: Kirstetter Geoffroy , Delestre Olivier , Lagrée Pierre-Yves , Popinet Stéphane , Josserand Christophe
Published: November 2021

Abstract. The French Riviera is very often threatened by flash floods. These hydro-meteorological events, which are fast and violent, have catastrophic consequences on life and property. The development of forecasting tools may help to limit the impacts of these extreme events. Our purpose here is to demonstrate the possibility of using b-flood (a subset of the Basilisk library http://basilisk.fr/, last access: 8 November 2021), which is a 2D tool based on the shallow-water equations and adaptive mesh refinement. The code is first validated using analytical test cases describing different flow regimes. It is then applied to the Toce river valley physical model produced by ENEL-HYDRO in the framework of the CADAM project and on a flash-flood case over the urbanized Toce area produced during the IMPACT project. Finally, b-flood is applied to the flash flood of October 2015 in Cannes in south-eastern France, which demonstrates the feasibility of using software based on the shallow-water equations and mesh refinement for flash-flood simulation in small watersheds (less than 100 km2) and on a predictive computational timescale.
Evaluation of a forest parameterization to improve boundary layer flow simulations over complex terrain
Authors: Quimbayo-Duarte Julian , Wagner Johannes , Wildmann Norman , Gerz Thomas , Schmidli Juerg
Published: November 2021

Abstract. We evaluate the influence of a forest parametrization on the simulation of the boundary layer flow over moderate complex terrain in the context of the Perdigão 2017 field campaign. The numerical simulations are performed using the Weather research and forecasting model using its large eddy simulation mode (WRF-LES). The short-term high resolution (40 m horizontal grid spacing) and long-term (200 m horizontal grid spacing) WRF-LES are evaluated for an integration time of 12 hours and 1.5 months, respectively, with and without forest parameterization. The short-term simulations focus on low-level jet events over the valley, while the long-term simulations cover the whole intensive observation period (IOP) of the field campaign. The results are validated using lidar and meteorological tower observations. The mean diurnal cycle during the IOP shows a significant improvement of the along-valley wind speed and the wind direction when using the forest parametrization. However, the drag imposed by the parametrization results in an underestimation of the cross-valley wind speed, which can be attributed to a poor representation of the land surface characteristics. The evaluation of the high-resolution WRF-LES shows a positive influence of the forest parametrization on the simulated winds in the first 500 m above the surface.
Reconstruction of wind and surge of the 1906 storm tide at the German North Sea Coast
Authors: Meyer Elke M. I. , Weisse Ralf , Grabemann Iris , Tinz Birger , Scholz Robert
Published: November 2021

Abstract. Storm tides represent a major threat to the low-lying German North Sea coast. Knowledge of extremes is essential for the design of reliable and robust coastal defences. A storm tide that occurred on 12–13 March 1906 along the German Bight coastline still represents one of the strongest events on record. For this event, detailed knowledge of atmospheric and hydrodynamic conditions is still lacking. To assess the potential impact of such an event on today’s coastline, century-long atmospheric reanalysis data together with a manual synoptic reconstruction based on archived weather data were used to drive a tide-surge model and to simulate water levels during the event. Sensitivity experiments were performed to estimate potential amplification of water levels that could have been caused by different time lags between the storm and the astronomical tide. Comparison between the model results and the limited available observational data indicated, that the water levels could be reasonably reconstructed using wind fields from the manual synoptic approach and some of the reanalysis ensemble members. The amplification potential was found to be low because the storm occurred during spring tide and shifts in the phase of the astronomic tide yielded only small changes in total water levels. To summarize, if pressure data are available at relevant locations, historical storm surges can be simulated with reanalysis products and also with a manual synoptic reconstruction.
Multiscale analysis of surface roughness for the improvement of natural hazard modelling
Authors: Brožová Natalie , Baggio Tommaso , D'Agostino Vincenzo , Bühler Yves , Bebi Peter
Published: November 2021

Abstract. Surface roughness influences the release of avalanches and the
dynamics of rockfall, avalanches and debris flow, but it is often not
objectively implemented in natural hazard modelling. For two study areas, a
treeline ecotone and a windthrow-disturbed forest landscape of the European
Alps, we tested seven roughness algorithms using a photogrammetric digital
surface model (DSM) with different resolutions (0.1, 0.5 and 1 m) and
different moving-window areas (9, 25 and 49 m2). The
vector ruggedness measure roughness algorithm performed best overall in distinguishing between
roughness categories relevant for natural hazard modelling (including shrub
forest, high forest, windthrow, snow and rocky land cover). The results with
1 m resolution were found to be suitable to distinguish between the
roughness categories of interest, and the performance did not increase with
higher resolution. In order to improve the roughness calculation along the
hazard flow direction, we tested a directional roughness approach that
improved the reliability of the surface roughness computation in channelised
paths. We simulated avalanches on different elevation models (lidar-based)
to observe a potential influence of a DSM and a digital terrain model (DTM)
using the simulation tool Rapid Mass Movement Simulation (RAMMS). In this way,
we accounted for the surface roughness based on a DSM instead of a DTM,
which resulted in shorter simulated avalanche runouts by 16 %–27 % in the
two study areas. Surface roughness above a treeline, which in comparison to
the forest is not represented within the RAMMS, is therefore underestimated.
We conclude that using DSM-based surface roughness in combination with DTM-based surface roughness
and considering the directional roughness is promising for achieving better
assessment of terrain in an alpine landscape, which might improve the natural
hazard modelling.
Ice volume and basal topography estimation using geostatistical methods and ground-penetrating radar measurements: application to the Tsanfleuron and Scex Rouge glaciers, Swiss Alps
Authors: Neven Alexis , Dall'Alba Valentin , Juda Przemysław , Straubhaar Julien , Renard Philippe
Published: November 2021

Abstract. Ground-penetrating radar (GPR) is widely used for determining mountain glacier thickness. However, this method provides thickness data only along the acquisition lines, and therefore interpolation has to be made between them. Depending on the interpolation strategy, calculated ice volumes can differ and can lack an accurate error estimation. Furthermore, glacial basal topography is often characterized by complex geomorphological features, which can be hard to reproduce using classical interpolation methods, especially when the field data are sparse or when the morphological features are too complex. This study investigates the applicability of multiple-point statistics (MPS) simulations to interpolate glacier bedrock topography using GPR measurements. In 2018, a dense GPR data set was acquired on the Tsanfleuron Glacier (Switzerland). These data were used as the source for a bedrock interpolation. The results obtained with the direct-sampling MPS method are compared against those obtained with kriging and sequential Gaussian simulations (SGSs) on both a synthetic data set – with known reference volume and bedrock topography – and the real data underlying the Tsanfleuron Glacier. Using the MPS modeled bedrock, the ice volume for the Scex Rouge and Tsanfleuron glaciers is estimated to be 113.9 ± 1.6 million cubic meters. The direct-sampling approach, unlike the SGS and kriging, allowed not only an accurate volume estimation but also the generation of a set of realistic bedrock simulations. The complex karstic geomorphological features are reproduced and can be used to significantly improve for example the precision of subglacial flow estimation.
Seasonal Sea Ice Prediction with the CICE Model and Positive Impact of CryoSat-2 Ice Thickness Initialization
Authors: Sun Shan , Solomon Amy
Published: November 2021

Abstract. The Los Alamos sea ice model (CICE) is being tested in standalone mode for its suitability for seasonal time scale prediction. The prescribed atmospheric forcings to drive the model are from the NCEP Climate Forecast System Reanalysis (CFSR). A built-in mixed layer ocean model in CICE is used. Initial conditions for the sea ice and the mixed layer ocean in the control experiments are also from CFSR. The simulated sea ice extent in the Arctic in control experiments is generally in good agreement with observations in the warm season at all lead times up to 12 months, suggesting that CICE is able to provide useful ice edge information for seasonal prediction. However, the ice thickness forecast has a positive bias stemming from the initial conditions and often persists for more than a season, limiting the model’s seasonal forecast skill. In addition, thicker ice has a lower melting rate in the warm season, both at the bottom and top, contributing to this positive bias. When this bias is removed by initializing the model using ice thickness data from satellite observations while keeping all other initial fields unchanged, both simulated ice edge and thickness improve. This indicates the important role of ice thickness initialization in sea ice seasonal prediction.
Integrating disability and developmental theories for an equitable inclusive education: towards transformative educational praxes
Authors: Podlucká Dušana
Published: November 2021

The US higher education institutions are legally bound to provide equal educational opportunities for diverse learners. This paper contends that despite the growing interest in implementing more inclusive pedagogy, those efforts still fall short of systematically addressing intersecting, oppressive, and anti-ableist practices in the classroom. I call for a theory that frames disability in the context of learning and development and overcomes dichotomized, reductionist and individualistic notions of disability and learning. Drawing on Critical Disability Studies, Vygotsky’s theory of defectology and the Transformative Activist Stance, this paper outlines a transformative pedagogy framework for inclusive, equitable, and anti-ableist education for all learners.
A inespecificidade em O pai da menina morta
Authors: Velasco Tiago  Monteiro
Published: November 2021

Este artigo procura fazer uma leitura do romance O pai da menina morta, de Tiago Ferro, a partir de conceitos como literatura inespecífica ou em campo expandido, que vêm sendo discutidos por Florencia Garramuño e Ana Kiffer, e, também, pelo de literatura pósautônoma, de Josefina Ludmer. O artigo discute o uso de fragmentos como construto narrativo nas escritas de si, na representação da memória e na impossibilidade de se narrar a dor. Por fim, procura-se aproximar O pai da menina morta às artes visuais, mais especificamente a obras instalativas.
An Examination of the Relationship between Depression, Loneliness, and Sociability in the Old Aged Community of District DG Khan
Authors: Abid Ayesha , Ahmad Khalil , Hussain Mussarat
Published: November 2021

The present study was aimed to assess depression, loneliness, and sociability among elderly people, as well as to assess the prevalence of elder abuse, and to draw conclusions about quality of life and its effect on elderly health in DG Khan's Tehsil Taunsa Sharif. The current research was conducted for pure academic purpose by 1st author and the results of this study were extracted from that academic dissertation. Moreover, this study was supervised by 2nd author and 3rd author contributed in analysis part of this research. In this regard, study was preceded by using quantitative research design. A sample of 200 elderly people was surveyed (both male and female at the time of interview). The elderly were interviewed with the help of their relatives. The interview schedule was used to collect data. Analysis of the data was carried out using the SPSS Software 21. The data was analyzed using the univariate regression test and the multivariate binary logistic regression test. The results of the binary logistic regression test showed that sociability get decreased as people age, depression and loneliness increased. Moreover, advancement in education of the respondents led to decrease in respondent’s depression, loneliness and sociability. Life satisfaction was affected by health and social support in different ways, depending on the person major determinants, such as education and nationality, as well as savings, income, frequency of contact with their children or relatives and neighbors, the number of known and trusted people in a village or city, as well as physical and mental health, were unaffected by age and gender. Additionally, it is recommended that in addition to primary care, health stakeholders should focus on health programs for the health promotion of elderly in order to protect the elderly from serious health problems, especially mental health problems.
Formulation and Evaluation of Gastroretentive Floating Tablets of Febuxostat
Authors: Rathi Sanjesh , Vaghela Sohansinh , Shah Raj , Shah Shrenik
Published: November 2021

The present research work done with an objective of preparation and evaluation of floating tablets of Febuxostat drug with Hydroxypropylenemethyl cellulose (HPMC), Polyox N-60K, Carbopol 934 P and Guar gum polymers. Floating tablets were based on effervescent approach using sodium bicarbonate a gas releasing agent. Direct compression method was used in present study for preparation of tablets. Effect of polymers was evaluated by studying drug release and floating time. In-vitro drug release profile indicates that sustained nature increased by increasing the concentration of polymer. The formulation containing Polyox N-60K and Carbopol 934 P in combination was optimized as it showed drug release up to 12hrs. Optimized formulation F18 was found stable during stability condition up to 1 month.
A Nutraceutical approach to enhance Reproductive longevity and Ovarian health using Curcuma longa in wistar Rats
Authors: Damodara Gowda K M , Shailaja S Moodithaya , Vishakh R Kedilaya , A K Nayanatara , Kumari N Suchetha
Published: November 2021

Aging is associated with various physiological, pathological and psychosocial alterations. This study evaluates the benefits of Curcumin by assessing reproductive aging indices and ovarian health in Wistar rats. Laboratory bred adult rats selected for the experiment. After 12 months of follow-up, the animals were grouped into Normal control rats, Sham control group, Curcumin-1(100 mg/kg body weight), Curcumin-2(200 mg/kg body weight) and Curcumin-3 (400 mg/kg body weight). For the duration of six months Curcumin dosage was administered. The experimental parameters included estrous cycle and histological evaluation of ovarian follicles. Data were analyzed using one-way ANOVA. The percentage of primordial follicles was significantly more (p<0.001) in all the groups when compared with other types of follicles. Prolonged increase (p=0.0001) in the Diestrus phase in animals treated with different dosages of Curcumin. The current study concludes that Curcumin, an active component of Curcuma longa contributes to the anti-aging properties.
Virtual Analysis of Condensed Pyrimidine Derivatives as COX II Inhibitors Potential Anti-inflammatory Agents
Authors: Khedkar S. A. , Patil J. S. , Sabale P. M.
Published: November 2021

Drug design and development is an interactive process includes process like molecular docking which involves virtual analysis of the derivatives against the protein targets. COXS are the groups of enzymes which plays vital role in the human process. COX II is important enzyme involved in the inflammation and can act as potential target for development of the potent anti-inflammatory agents. Pyrimidine is one of the most utilized heterocyclic scaffolds for the development of therapeutic agents due to its role in the nucleic acid and proteins in the human body. The present communication deals with docking analysis of virtually designed 58 condensed pyrimidine derivatives as potential anti-inflammatory agents. The derivatives were designed and virtually screened via molecular docking against the COX-II crystal structure to identically the potential leads.
Severe Acute Respiratory Syndrome Coronavirus-2 Emergence and Its Treatment with Alternative Medicines: A Review
Authors: Muhammad Ansori Arif Nur , Kharisma Viol Dhea , Fadholly Amaq , Rani Tacharina Martia , Antonius Yulanda , Parikesit Arli Aditya
Published: November 2021

Known as the causal factor of the recent global COVID-19 pandemic, any SARS-CoV-2 is not the only coronavirus that has constituted a menace to society and taken thousands of human lives. Two previous pandemics were also led by coronaviruses; such as the MERS-CoV in 2012 and another SARS-CoV in 2002. Only five months into existence, SARS-CoV-2 transmitted infection to approximately 75 million people and it has led to more than 1.5 million of deaths all over the world. Unfortunately, there has not been any specific treatment yet for COVID-19 yet and its control is purely empirical. The examinations of the parity between SARS-CoV-2 and SARS-CoV, in terms of their genomics, origin, epidemiology, and pathogenesis, suggested that we may use the previous data of MERS-CoV or SARS-CoV as a guideline for uncovering the effective approach to strive against SARS-CoV-2. Various studies have reported the positive effects of numerous phytochemical compounds against SARS-CoV and MERS-CoV. Interestingly, this idea has been emplyed for SARS-CoV-2, and in silico screening of phytochemical compounds has been performed for identifying the potential candidates for COVID-19 treatment. Curcumin is an example of a natural compound which was demonstrated as potent candidate contrary to SARS-CoV-2 protease derived from the in silico studies. Herein, the occurrence of SARS-CoV-2 and the aplication of alternative medicines for treating coronavirus diseases are briefly reviewed.
Liquisolid Compacts Technique of Poor Water Soluble Drugs:
An Overview
Authors: Bhavya E. , Dhere M.D.
Published: November 2021

Liquisolid technique is new and promising method that can use to enhance the dissolution rate of poorly water soluble drugs. Liquisolid compact technique is based upon the dissolving the drug in a suitable non-volatile solvent by using carrier and coating material for the conversion of acceptable flowing and compressible powders. By applying the mathematical models the carrier and coating materials optimized. In this case the drug is almost solubilised in the solvent or molecularly dispersed state which contributes the enhanced drug dissolution.
A Review on Film Forming Drug Delivery Systems
Authors: Mansoor Al-Jarsha Hayder Yahya , Ghareeb Mowafaq M. , Hussein Ahmed A.
Published: November 2021

Conventional dosage forms for topical and transdermal drug delivery have several disadvantages related mainly to its poor skin permeation and patient compliance. Many approaches have been developed to improve these dosage forms. Film forming drug delivery systems represents a recent advancement in this field. It provides improved patient compliance with enhanced skin permeation of drugs. In its simplest form, these consist of a polymeric solution, usually in a supersaturated state, in a suitable solvent. A plasticizer is usually added to improve the flexibility and enhance the tensile strength to the film. It is also possible to control and sustain the drug release from the films by controlling the polymeric content, concentration of plasticizer, or formulation with other additives. In this review, we are summarizing the mechanism of formation of these films as well as its types and possible applications. The main ingredients, properties, and evaluation of the various film forming delivery systems are also discussed.
الأخلاقيات المهنية ومدى أهميتها لدى أعضاء هيئة التدريس كما يراها رؤساء الأقسام بالجامعات السعودية
Authors: بن سعد السليمي د. خالد
Published: November 2021

هدفت هذه الدراسة التعرف على الأخلاقيات المهنية ومدى أهميتها لدى أعضاء هيئة التدريس كما يراها رؤساء الأقسام بالجامعات السعودية من وجهة نظر رؤساء الأقسام بجامعة أم القرى بمكة المكرمة خلال العام الدراسي (1436هـ/1437هـ) والذين بلغ عددهم (183) فرداً موزعين على (39) كلية ومعهد، وتكونت عينة الدراسة من (119) فرداً من رؤساء الأقسام، وقد تم جمع بيانات الدراسة باستخدام استبانه من إعداد الباحث اشتملت  على (72) عبارة مقسمة على خمس محاور، واستخدم الباحث المنهج الوصفي التحليلي، ولتحليل البيانات إحصائياً استخدم الباحث برنامج الحزم الإحصائية للدراسات الاجتماعية (SPSS.20)، ومن أهم النتائج التي توصل إليها الباحث حول أهمية الأخلاقيات المهنية لأعضاء هيئة التدريس هي: أن يزوّد الطلاب بلوائح الاختبارات وخطة توزيع الدرجات، وأن يحترم زملاءه أعضاء هيئة التدريس بالقسم، وأن يشارك في اجتماعات القسم، وأن يحرص على المشاركة في المؤتمرات والندوات العلمية، وأن يسعى لتلبية طموحات وتطلعات المجتمع المحلي. كما أظهرت النتائج أنه توجد فروق عند مستوى الدلالة (0.05 ≥  α ) بين متوسطات استجابات أفراد العينة في تقديرهم لأهمية الأخلاقيات المهنية بالنسبة لأعضاء هيئة التدريس في الجامعات السعودية في متغير التخصص (نظري/علمي) لصالح النظري، وأيضاً عدم وجود فروق ذات دلالة إحصائية بين أفراد العينة حول تقديرهم لأهمية الأخلاقيات المهنية بالنسبة لأعضاء هيئة التدريس في الجامعات السعودية في متغير الدرجة العلمية، عدد سنوات الخبرة في التدريس الجامعي، وعدد سنوات الخبرة في مجال العمل الإداري الأكاديمي. وأوصي الباحث في نهاية الدراسة يجب تطوير الأخلاقيات المهنية لأعضاء هيئة التدريس بالجامعات السعودية المذكورة في متغيرات الدراسة الخمسة.
Effect of nitrogen fertilization on growth, yield and ethanol production of sweet sorghum (Sorghum bicolor (L. Moench)
Authors: Elnasikh Maria H. , Ibrahium Mulhima Sh.
Published: November 2021

Field trials were carried out to test the effect of nitrogen fertilization on the growth, stalks and juice yield, sugar content and ethanol production of sweet sorghum. The experiments were carried out on winter 2013 in the Domonstration Farm of the Faculty of Agriculture, University of Khartoum, Shambat and Experimental Farm of the Soba Research Station for Reclamation of Saline and Sodic soils. The treatments comprised the addition of nitrogen fertilizer (urea) at three levels (0, 43 and 86 Kg N ha-1) and two sweet sorghum genotypes (Baladi and RSSS.11), arranged in randomized complete block design replicated 4 times. Results indicated that there were significant (P ≥ 0.05) differences between genotypes in stem diameter at Soba location, stalk height and leaves area at Shambat location, number of green leaves per plant, stalk juice and ethanol yield in both locations. With the genotype RSSS.11 generally superior over genotype Baladi. Nitrogen fertilization increased significantly (P ≥ 0.05) number of green leaves per plant and leaves area at Shambat location and plant height and juice and ethanol yield in both locations. With the Soba location recorded the highest values over Shambat location and 86 kg N ha-1 recorded the highest ethanol yield (255.6l h-1).
Islamic Utopianism: Key Concepts from the Quranic Story of Adam’s Creation
Authors: Bajaber Musab
Published: November 2021

This article argues that the story of Adam’s creation in the Quran establishes some early terminology on Islamic utopianism that later influenced the utopian drive in the Muslim world. It also argues that proper understanding of Islamic utopianism calls for Bloch’s redefinition of the term and his differentiation between utopian function, content, and form and between abstract and concrete utopias. Throughout the article, the writer tracks the formation of abstract and concrete utopias in the Quranic story of Adam and his mission on Earth. The writer then explains and illustrates how the Quranic story established three terms crucial to the formation of many secular and religious utopian articulations in Islamic history: Ḵilāfa, istiʿmār, and ṣirāṭ mustaqīm. This article is useful to researchers interested in utopianism beyond the Western context because it provides preliminary research on Islamic utopianism that has been scarcely studied so far
Zones of Eden: Utopian Fragments in Raymond Williams’s The Fight for Manod and E. P. Thompson’s The Sykaos Papers
Authors: Efstathiou Christos
Published: November 2021

The article offers a comparative account of Raymond Williams’s The Fight for Manod and E. P. Thompson’s The Sykaos Papers and examines their depiction of social and political realities during the late twentieth century, the meeting of socialist and ecological concerns in their fictional world, as well as their allegiance to William Morris’s utopian vision. The article also aims to place Williams’s and Thompson’s fiction in an often-neglected thread of the modern utopian tradition, which tends to combine utopian and dystopian elements.
Virtual water flow and water footprint as optimizer of water resource management in the state of Ceará, Brazil
Authors: Leite Ivana Sampaio , Sabiá Rodolfo José , Matos Andrezza Pereira , Silva Camila Cavalcante
Published: November 2021

The water exported indirectly by sending products to other countries, or vice versa, is called a virtual water flow and this can be measured through water footprint (WF) calculations, which represent the embedded water needed to manufacture a product. This present study aims to analyze the virtual water flow and the WF of the main products exported by municipalities in the state of Ceará in the year 2019, in order to enhance the management of the state’s water resources. Analytical hierarchy process (AHP), the most commonly used multicriteria decision-making method in the world, was used to determine which product is more sustainably produced by the municipalities of Ceará, with the criteria: WF, price, and volume exported. The alternatives are at least two of the seven categories of products exported by the state where the “fruit or vegetable juices” class was preferred as the most sustainable. It was found that most cities in the state that export agricultural products use only one basin, which can lead to very low reservoir levels, while the other hydrographic basins in the state are underused. It is worth noting that the Metropolitan Basin concentrates on 11 out of 32 municipalities that export abroad and that it is responsible for supplying more than 4,074,730 inhabitants, according to Brazilian Institute of Geography and Statistics (IBGE, 2019).
Survey of wildlife rescued and treated from 2014 to 2016 in Joinville (SC), Brazil
Authors: Barbosa Carolina Konkel , Gneiding José Eduardo Basilio de Oliveira , Ribeiro Túlio Tácito , Iachinski Edevaldo Antonio , Gonçalves Igor Christian Magno , Pimpão Cláudia Turra
Published: November 2021

Natural ecosystems are in constant conflict with the growing and disordered urban expansion, arising from the mismanagement of human developments and infrastructure, facing an accelerated rate of deforestation and defaunation. The intense pressure on natural environments impacts the local fauna through various incidents, generating high mortality, such as hit-and-run, window-crashing, attacks by domestic animals, dissemination of diseases and electrocution. The purpose of this study was to carry out a retrospective survey of the wild fauna rescued and treated at a clinic associated with the environmental police in the region of Joinville - SC. A total of 379 wild animals were treated at the clinic from 2014 to 2016. Of these, 262 (69.13%) were birds, 107 (28.23%) mammals, 9 (2.37%) reptiles and 1 (0.26%) amphibian. The main causes of referral for clinical care were due to trauma (50.66%), seizures (1.32%) and other causes (48.02%), such as home invasion and orphaned puppies. Among the reasons for traumas, pedestrian accidents were the most prevalent, representing 39.58% of the cases treated, followed by animals found to be debilitated without a defined cause (31.77%), attack by domestic animals (14.58%) and window-crashing (9.89%). The data obtained in this study show a rich diversity of species in Joinville. These species are exposed to several anthropogenic challenges and barriers derived mainly from intense displacement and human invasion, causing many animals to move in order to adapt to urban areas.
Expansion of photovoltaic systems in multicampi higher education institutions: evaluation and guidelines
Authors: Da Silva Osvaldo Augusto Vasconcelos de Oliveira Lopes , Moita Neto José Machado , Lira Marcos Antônio Tavares , Morais Fabrício Higo Monturil de
Published: November 2021

Considering the multicampi organizational structure of higher education institutions (HEIs), the expansion of photovoltaic (PV) systems previously installed in the facilities, the great potential for PV generation in Brazil, and the 2030 Agenda, the general goal of this research study is to evaluate and promote the expansion of the aforementioned PV systems. For this purpose, the PV system installed at the Federal Institute of Education, Science and Technology of Piauí comprising a future expansion is characterized by a thorough literature and documentary research. The solar resource available at the campuses of the institution was estimated using the second version of the Brazilian Atlas of Solar Energy. The technical–economic viability of the system expansion is assessed through the average parameters and minimum performance indexes required by the institution. Thus, it is possible to prove the effectiveness of the methodology to identify investment priorities and guide the construction and expansion of other PV systems, confirming that this process is technically and economically feasible as associated with strategic adherence, also bringing several environmental benefits.
Effect of a temperature rise on metal toxicity for the aquatic biota: a systematic review
Authors: Nin Carla Juliana , Rodgher Suzelei
Published: November 2021

Ecosystems are subject to various stress factors, such as temperature rises due to climate changes and metal disposal. Thermal stress can amplify or mask the effects of metals on aquatic organisms. This study aims to carry out a systematic review on the effects of temperature rises due to climate changes on the toxicity of metals for freshwater organisms. Searches were made in different electronic databases and article selection was based on the following inclusion criteria: concordance with the question of a systematic review; publication in English, Spanish, and Portuguese between 1960 and 2020; and the use of standard methodology. Forty-three articles were included, which were classified with respect to the year and country of publication, test-organisms and metals studied, temperatures tested, and the effects observed. In 80% of the studies analyzed, a temperature rise was responsible for increasing the toxicity of metals for the aquatic organisms. The temperatures studied contemplated the temperature rise predicted by the Intergovernmental Panel for Climate Change at the end of the 21st century. Brazil stood out among the countries for having the greatest number of research studies in this area, although there is still the need for an increase in studies in tropical climate regions. Based on the literature review, it was shown that the metals most studied were copper and cadmium and the test-organisms most used in the research projects were fish. The information obtained from ecotoxicological studies is essential to predict the effects and prevent the risks associated with the metal contamination of aquatic ecosystems due to climate changes.