bluuebunny/crossref_metadata_2025 huggingface dataset:
Azo Polymer Janus Particles Possessing Photodeformable and Magnetic‐Field‐Responsive Dual Functions
Authors: Zhou Xinran , Du Yi , Wang Xiaogong
Published: June 2016

It is of great fundamental and practical significance to endow Janus particles with various field‐responsive properties. In this study, a new strategy with a wide range of application possibilities is developed to fabricate JPs composed of a methacrylate‐based azo polymer, polystyrene, and Fe3O4 nanoparticles. The JPs are obtained through microphase separation in a confined volume of the dispersed droplets. The azo polymer and PS are incorporated in JPs in a core‐compartmentalized manner, and Fe3O4 are proved to exist in the azo polymer phase. The JPs show responsive movement in the magnetic field and can be easily oriented with the help of the field. By variation of the intersection angle between the particle symmetrical axis and the polarization direction of the linearly polarized laser beam, different deformation modes are feasibly achieved for the JPs. By exploiting the dual‐responsive properties, JPs with designed shapes can be fabricated by exposing the JPs to linearly polarized light.
Elucidation of the interaction of human serum albumin with anti‐cancer sipholane triterpenoid from the Red Sea sponge
Authors: Ali Mohd. Sajid , Amina Musarat , Al‐Lohedan Hamad A. , Al Musayeib Nawal M.
Published: June 2016

A sipholane triterpenoid, named sipholenone A, with anti‐cancer properties was isolated from the Red Sea sponge Siphonochalina siphonella and characterized by proton and carbon‐13 nuclear magnetic resonance (1H NMR and 13C NMR) spectroscopies. The goal of this study was to visualize the binding of this triterpenoid with human serum albumin (HSA) and to determine its binding site on the biomacromolecule. The interaction was visualized using fluorescence quenching, synchronous fluorescence, far‐ and near‐UV circular dichroism (CD), UV–visible and Fourier transform‐infrared (FT‐IR) spectroscopies. UV–visible spectroscopy indicated the formation of a ground‐state complex as a result of the interaction. Sipholenone A quenches the fluorescence of HSA via a static quenching mechanism. A small blue shift in the fluorescence quenching profiles suggested the involvement of hydrophobic forces in the interaction. Sipholenone A binding takes place at site I of subdomain II A with a 1:1 binding ratio, as revealed by displacement binding studies using warfarin, ibuprofen and digitoxin. Far‐UV CD and FT‐IR studies showed that the binding of sipholenone A to HSA also had a small effect on the protein's secondary structure with a slight decrease in the α‐helical content. Several thermodynamic parameters were calculated, along with Forster's radiative energy transfer analysis.
Quantification of lipid modified estrogenic derivative (ESC8) in rat plasma by LC‐MS: application to a pharmacokinetic study
Authors: Ahmad Ajaz , Mondal Sujan Kumar , Jan Basit Latief , Mukhopadhyay Debabrata , Banerjee Rajkumar , Alkharfy Khalid M.
Published: June 2016

A lipid‐conjugated, estrogenic derivative molecule, ESC8, compared with other estrogenic molecules, encourages cell death in both ER‐positive and ER‐negative breast cancer cells. A rapid and highly sensitive assay method has been developed and validated for the estimation of a ESC8 in rat plasma using liquid chromatography coupled with mass spectrometry under positive‐ion mode with electrospray ionization. The sample process includes using methanol for precipitation of ESC8 and dextromethorphan (internal standard, IS) from plasma. Chromatographic separation was achieved with methanol–water–formic acid (70:30:0.1% v/v/v) pumped at a flow rate of 0.3mL/min and a C18 column (50 × 2.1 mm i.d., 1.7 μm particle size) with a total run time of 5 min. The m/z ions monitored were 568.5 and 272.1 for ESC8 and IS, respectively. The lower limit of quantitation achieved was 1.08 ng/mL and linearity was observed from 5 to 500 ng/mL. The intra‐ and inter‐day precisions were <4%. The proposed method was successfully applied to a preliminary pharmacokinetic study of ESC8 liposomal formulation following an intraperitoneal administration of 3.67 mg/kg in rats. The concentrations of ESC8 in plasma were quantifiable up to 36 h. The peak concentration of ESC8 was found to be 110.72 ng/mL, the area under the concentration–time curve was 1625.23ng/mL h and the half‐life was 11.72 h.
Manage interpretation of medical, forensic evidence in Title IX hearings
Authors: McCarthy Claudine
Published: June 2016

The Office for Civil Rights has called attention to higher ed professionals' lack of training in medical and forensic evidence, including results of medical examinations and drug or alcohol tests.
Plan carefully for a safe commencement day
Authors: Miles David
Published: June 2016

With the end of an academic year behind us, those of us who work in university public safety can exhale and be glad we made it through another year.
Focus on education, technology to protect large campus
Authors: Sutton Halley
Published: June 2016

Policing a large public campus can be akin to policing a small city, as Lamine Secka, chief of police for San Diego State University, well knows. SDSU, which is home to 37,000 students and sees approximately 45,000–50,000 people on campus per day, is located in the busiest part of San Diego and is a very open campus. “It's very difficult to tell when you're on campus rather than just the surrounding community,” Secka said, an issue that has led to a close working relationship between the SDSU campus police force and the San Diego Police Department.
Reduce assault risk by supervising sports camp employees as closely as campers
Authors: Wilson Mark
Published: June 2016

College sports camps should provide head coaches and athletics departments with a competitive advantage. When competing to hire top assistant coaches or program assistants, a head coach can supplement assistant coach salaries with camp profits. The recent uproar over satellite camps reinforced the prominent role camps play in the recruiting process.
Student‐athletes' brain health can increase performance, reduce risk
Authors: McCarthy Claudine
Published: June 2016

CLEARWATER BEACH, FLA. — When college athletics administrators, coaches and athletic trainers try to find ways to improve their student‐athletes' performance and well‐being, they're likely looking in all the wrong places, which leaves student‐athletes at risk. It happens because many in college athletics don't realize brain health is inseparable from high performance and quality of life, according to the latest scientific research, explained Dr. John P. Sullivan, a clinical sport psychologist and sport scientist.
Follow 3 key tips for engaging your direct reports
Authors: Jarvis Kimberly , Munin Art
Published: June 2016

Staff members qualify as one of the strongest resources for helping college athletics departments to advance their mission and support their student‐athletes. And that's why supporting, developing and engaging the individuals we supervise are central components of the work of college athletics administrators.
Did student‐athletes' discrimination claims survive university's motion to dismiss?
Authors: Gelpi Aileen
Published: June 2016

Haley Videckis and Layana White were members of the Pepperdine University women's basketball team, and Ryan Weisenberg was the team's head coach. Videckis and White were in a dating relationship while they were on the basketball team. They sued Pepperdine, alleging they were subjected to intrusive and discriminatory actions, and that Weisenberg and his staff harassed them in an effort to force them to quit the team because of their lesbian relationship.
Computational simulations in coronary bifurcations: Paving the future of interventional planning
Authors: Collet Carlos , Serruys Patrick W.
Published: June 2016

Key Points

Anatomical evaluation is of paramount importance in the treatment of bifurcation lesions.

Left main coronary artery bifurcation geometry differs from left anterior descending artery/diagonal and circumflex artery/obtuse marginal bifurcations.

Individualized approach with pre‐procedural planning has the potential to improve outcomes after bifurcation treatment.
To aspirate or not!: The question may be not if, but when
Authors: Tommaso Carl L.
Published: June 2016

Key Points

Current guidelines indicate that routine aspiration thrombectomy (AT) has a level III indication and AT is only indicated for “bail‐out” indications.

“Bail‐out” situations are not well defined.

The AT catheter may still be necessary and have other uses such as distal contrast or drug delivery.
Supramolecular Reaggregation of Acetyl Salicylic Acid‐4,4′Dipyridyl Cocrystals from Salicylic Acid‐4,4′Dipyridyl Cocrystals
Authors: Lee Kyeong‐Sill , Kim Kwang‐Joo , Ulrich Joachim
Published: June 2016

Screening of the change mechanism of salicylic acid‐4,4′dipyridyl (SAA‐4,4′dipy) cocrystals to acetyl salicylic acid‐4,4′dipyridyl (ASA‐4,4′dipy) cocrystals was performed and their transformation investigated. Cocrystals of SAA‐4,4′dipy are concomitantly formed in ASA/4,4′dipyridyl/ethanol solutions, resulting from ASA decomposition. Eventually, cocrystals of ASA‐4,4′dipy are obtained from a sequence of in situ reactions by controlling the operating conditions. Both cocrystals have the same hydrogen bonding interaction between the drug molecules. The ketene functional group decomposed in salicylic acid cocrystal formation reaggregates during solution‐mediated cocrystallization that leads to the formation of ASA cocrystals.
A Valence Tautomeric Dinuclear Copper Tetrakisguanidine Complex
Authors: Wiesner Sven , Wagner Arne , Kaifer Elisabeth , Himmel Hans‐Jörg
Published: June 2016

We report on the first valence tautomeric dinuclear copper complex, featuring 2,3,5,6‐tetrakis(tetramethylguanidino)pyridine as a bridging redox‐active GFA (guanidino‐functionalized aromatic) ligand. The preferred electronic structure of the complex is massively influenced by the environment. In the solid state and in nonpolar solvents a paramagnetic, dinuclear CuII complex with a neutral GFA ligand is present. In polar solvents, the electronic structure changes to a diamagnetic, dinuclear CuI complex with a twofold‐oxidized GFA ligand. Using acetone as a solvent, both electronic structures are accessible due to a temperature‐dependent equilibrium between the two valence tautomeric complexes. Our results pave the way for a broader use of valence tautomeric transition‐metal complexes in catalytic reactions since anionic coligands can now be tolerated owing to the neutral/positively charged GFA ligand.
Copper(II) and Zinc(II) Complexes of Conformationally Constrained Polyazamacrocycles as Efficient Catalysts for RNA Model Substrate Cleavage in Aqueous Solution at Physiological pH
Authors: Bím Daniel , Svobodová Eva , Eigner Václav , Rulíšek Lubomír , Hodačová Jana
Published: June 2016

As part of a quest for efficient artificial catalysts of RNA phosphodiester bond cleavage, conformationally constrained mono‐ and bis‐polyazamacrocycles in which tri‐ or tetraazaalkane chains link the ortho positions of a benzene ring were synthesized. The catalytic activities of mono‐ and dinuclear copper(II) and zinc(II) complexes of these polyazamacrocycles towards cleavage of the P−O bond in 2‐hydroxypropyl‐4‐nitrophenylphosphate (HPNP) in aqueous solution at pH 7 have been determined. Only the complexes of the ligands incorporating three nitrogen atoms in a macrocycle proved to be capable of efficiently catalyzing HPNP transesterification. The dinuclear complexes were found to be approximately twice as efficient as their mononuclear counterparts, and exhibited Michaelis–Menten saturation kinetics with calculated rate constants of kcat≈10−4 s−1. By means of quantum chemical calculations (DFT/COSMO‐RS), several plausible reaction coordinates were described. By correlating the calculated barriers with the experimental kinetic data, two possible reaction scenarios were revealed, with activation free energies of 20–25 kcal mol−1.
Direct, Sequential, and Stereoselective Alkynylation of C,C‐Dibromophosphaalkenes
Authors: Shameem Muhammad A. , Esfandiarfard Keyhan , Öberg Elisabet , Ott Sascha , Orthaber Andreas
Published: June 2016

The first direct alkynylation of C,C‐dibromophosphaalkenes by a reaction with sulfonylacetylenes is reported. Alkynylation proceeds selectively in the trans position relative to the P substituent to afford bromoethynylphosphaalkenes. Owing to the absence of transition metals in the procedure, the previously observed conversion of dibromophosphaalkenes into phosphaalkynes through the phosphorus analog of the Fritsch–Buttenberg–Wiechell rearrangement is thus suppressed. The bromoethynylphosphaalkenes can subsequently be converted to C,C‐diacetylenic, cross‐conjugated phosphaalkenes by following a Sonogashira coupling protocol in good overall yields. By using the newly described method, full control over the stereochemistry at the P=C double bond is achieved. The substrate scope of this reaction is demonstrated for different dibromophosphaalkenes as well as different sulfonylacetylenes.
ChemInform Abstract: Structural, Magnetic, Magneto‐Caloric and Moessbauer Spectral Study of Tb2Fe17 Compound Synthesized by Arc Melting.
Authors: Charfeddine S. , Zehani K. , Bessais L. , Korchef A.
Published: June 2016

Hexagonal Tb2Fe17 is prepared by repeated arc melting of the elements without further annealing.
ChemInform Abstract: Li3Mo4P5O24: A Two‐Electron Cathode for Lithium‐Ion Batteries with Three‐Dimensional Diffusion Pathways.
Authors: Wen Bohua , Liu Jue , Chernova Natasha A. , Wang Xiaoya , Janssen Yuri , Omenya Fredrick , Khalifah Peter G. , Whittingham M. Stanley
Published: June 2016

The new title compound is synthesized by decomposition (350 °C, 6 h) of a gel obtained from an aqueous mixture of MoO3, NH4H2PO4, Li2CO3, and oxalic acid, followed by heating the product twice at 650 and 750 °C for 2 h.
ChemInform Abstract: All‐Metal Antiaromaticity in Sb4‐Type Lanthanocene Anions.
Authors: Min Xue , Popov Ivan A. , Pan Fu‐Xing , Li Lei‐Jiao , Matito Eduard , Sun Zhong‐Ming , Wang Lai‐Sheng , Boldyrev Alexander I.
Published: June 2016

Compounds (IIIa—e) crystallize in the triclinic space group P$\bar 1$ with Z = 2 (single crystal XRD).
ChemInform Abstract: Highly Efficient Transition Metal Nanoparticle Catalysts in Aqueous Solutions.
Authors: Wang Changlong , Ciganda Roberto , Salmon Lionel , Gregurec Danijela , Irigoyen Joseba , Moya Sergio , Ruiz Jaime , Astruc Didier
Published: June 2016

A tris(triazolyl)‐polyethylene glycol amphiphilic ligand is designed and successfully used as highly efficient catalyst in combination with various transition metal nanoparticles in click reactions, Suzuki—Miyaura couplings, as well as transfer hydrogenation reactions.
ChemInform Abstract: A Copper‐Based Metal—Organic Framework Acts as a Bifunctional Catalyst for the Homocoupling of Arylboronic Acids and Epoxidation of Olefins.
Authors: Parshamoni Srinivasulu , Telangae Jyothi , Sanda Suresh , Konar Sanjit
Published: June 2016

Biaryls are prepared by the homocoupling of arylboronic acids and epoxides are obtained by epoxidation of olefins under mild conditions using a Cu2Br2‐based metal—organic framework as catalyst.
ChemInform Abstract: Visible‐Light Photoredox‐Catalyzed C—H Difluoroalkylation of Hydrazones Through an Aminyl Radical/Polar Mechanism.
Authors: Xu Pan , Wang Guoqiang , Zhu Yuchen , Li Weipeng , Cheng Yixiang , Li Shuhua , Zhu Chengjian
Published: June 2016

A highly (E)‐stereoselective photoredox process for the direct C(sp2)—H bond difluoroalkylation of aldehyde‐derived hydrazones is reported.
ChemInform Abstract: Tris(1,2‐diphenylethylenediamine)cobalt(III) Complexes: Chiral Hydrogen Bond Donor Catalysts for Enantioselective α‐Aminations of 1,3‐Dicarbonyl Compounds.
Authors: Kumar Anil , Ghosh Subrata K. , Gladysz John A.
Published: June 2016

This study expands the applicability of chiral Werner complexes, based upon ethylenediamine chelates as hydrogen bond donor catalysts for the enantioselective addition of dicarbonyl compounds to di‐tert‐butyl azodicarboxylate.
ChemInform Abstract: Rhodium‐Catalyzed Bis‐Hydroaminomethylation of Linear Aliphatic Alkenes with Piperazine.
Authors: Seidensticker Thomas , Vosberg Jonas M. , Ostrowski Karoline A. , Vorholt Andreas J.
Published: June 2016

A general protocol for bis‐hydroaminomethylation of piperazine with terminal olefins is developed.
ChemInform Abstract: Cobalt‐Catalyzed Bis‐Alkynylation of Amides via Double C—H Bond Activation.
Authors: Landge Vinod G. , Jaiswal Garima , Balaraman Ekambaram
Published: June 2016

The mono‐ and bis‐alkynylation of amides (I) and (IV) proceeds readily in the presence of a cobalt catalyst.
ChemInform Abstract: Pyrrole as a Directing Group: Regioselective Pd(II)‐Catalyzed Alkylation and Benzylation at the Benzene Core of 2‐Phenylpyrroles.
Authors: Wiest Johannes M. , Poethig Alexander , Bach Thorsten
Published: June 2016

The Pd‐catalyzed ortho‐alkylation of 2‐phenylpyrroles (I) and (IX) gives rise to 2‐substituted benzenes (III) and (XI), whilst the benzylation of substrates (XII) affords 2,6‐dibenzylbenzenes (XIII).
ChemInform Abstract: Unusual, Chemoselective Etherification of 2‐Hydroxy‐1,4‐naphthoquinone Derivatives Utilizing Alkoxymethyl Chlorides: Scope, Mechanism and Application to the Synthesis of Biologically Active Natural Product (.+‐.)‐Lantalucratin C.
Authors: Ogata Tokutaro , Yoshida Tomoyo , Shimizu Maki , Tanaka Manami , Fukuhara Chie , Ishii Junko , Nishiuchi Arisa , Inamoto Kiyofumi , Kimachi Tetsutaro
Published: June 2016

A new method for the chemoselective etherification of 2‐hydroxy‐1,4‐naphthoquinone derivatives utilizing alkoxymethyl chlorides is studied.
ChemInform Abstract: Brook/Elimination/Aldol Reaction Sequence for the Direct One‐Pot Preparation of Difluorinated Aldols from (Trifluoromethyl)trimethylsilane and Acylsilanes.
Authors: Decostanzi Melanie , Godemert Jeremy , Oudeyer Sylvain , Levacher Vincent , Campagne Jean‐Marc , Leclerc Eric
Published: June 2016

An one‐pot preparation of difluorinated aldols directly from the Ruppert—Prakash reagent, acyltrimethylsilanes and aldehydes is reported.
ChemInform Abstract: Thioetherification via Photoredox/Nickel Dual Catalysis.
Authors: Jouffroy Matthieu , Kelly Christopher B. , Molander Gary A.
Published: June 2016

The photoredox thioetherification of (hetero)aryl bromides (II) with thiolsilicate (I) leads to a variety of (hetero)aryl propyl thioethers (III).
ChemInform Abstract: CaF2 Catalyzed Chemoselective Oxidation of Sulfides to Sulfoxides with Hydrogen Peroxide under Solvent‐Free Conditions.
Authors: Rostami Amin , Pourshiani Omid , Gheisarzade Sajede
Published: June 2016

Various aromatic and aliphatic sulfides are oxidized under eco‐friendly solvent‐free conditions in short reaction times.
ChemInform Abstract: Organocatalytic Enantioselective Synthesis of Tetrahydrofluoren‐9‐ones via Vinylogous Michael Addition/Henry Reaction Cascade of 1,3‐Indandione‐Derived Pronucleophiles.
Authors: Moehlmann Lennart , Chang Geng‐Hua , Madhusudhan Reddy G. , Lee Chia‐Jui , Lin Wenwei
Published: June 2016

An asymmetric vinylogous Michael addition/Henry cyclization cascade with 1,3‐indandione derivatives (I), (IV), and (VI) and nitro alkenes affords highly substituted tetrahydrofluorenones.
ChemInform Abstract: Synthesis of Bridged Heterocycles via Sequential 1,4‐ and 1,2‐Addition Reactions to α,β‐Unsaturated N‐Acyliminium Ions: Mechanistic and Computational Studies.
Authors: Yazici Arife , Wille Uta , Pyne Stephen G.
Published: June 2016

Sequential 1,4‐ and 1,2‐addition reactions of allylsilanes and boranes to indolizidine and quinolizidine α,β‐unsaturated N‐acyliminum ions give access to tricyclic bridged N‐heterocyclic systems.
ChemInform Abstract: Br2 as a Novel Lewis Acid Catalyst for Friedel—Crafts Alkylation of Indoles with α,β‐Unsaturated Ketones.
Authors: Liang Deqiang , Li Xiangguang , Zhang Wanshun , Li Yanni , Zhang Mi , Cheng Ping
Published: June 2016

Under the catalysis of 3—10 mol% of Br2, the Michael addition proceeds with high efficiency and broad substrate scope to afford the corresponding β‐indolylketone derivatives.
ChemInform Abstract: Rhodium‐Catalyzed Cyclization of 2‐Ethynylanilines in the Presence of Isocyanates: Approach Toward Indole‐3‐carboxamides.
Authors: Mizukami Akiho , Ise Yumi , Kimachi Tetsutaro , Inamoto Kiyofumi
Published: June 2016

A completely novel route toward variously substituted indolecarboxamides is achieved by a tandem‐type cyclization‐addition sequence in the presence of a rhodium catalyst.
ChemInform Abstract: One‐Pot Synthesis of Multisubstituted Benzimidazoles via Sequential Ugi and Catalytic Aza‐Wittig Reaction Starting from 2‐Aminobenzoyl Azides.
Authors: Yan Yan‐Mei , Rao Yong , Ding Ming‐Wu
Published: June 2016

This four‐component reaction of 2‐aminobenzoyl azides, aldehydes, carboxylic acids, and isocyanides gives Ugi‐products as intermediates, which are converted to isocyanates in refluxing toluene.
ChemInform Abstract: Remodeling and Enhancing Schmidt Reaction Pathways in Hexafluoroisopropanol.
Authors: Motiwala Hashim F. , Charaschanya Manwika , Day Victor W. , Aube Jeffrey
Published: June 2016

The combination of TMSN3 in the presence of triflic acid gives tetrazoles as the major products.
ChemInform Abstract: Cobalt‐Catalyzed Annulation of Salicylaldehydes and Alkynes to Form Chromones and 4‐Chromanones.
Authors: Yang Junfeng , Yoshikai Naohiko
Published: June 2016

Reactions of salicylaldehyde with internal alkynes in the presence of a catalyst generated from zinc, cobalt dibromide, and 1,2‐bis(dicyclohexylphosphino)ethane give a dehydrogenative annulation product (chromone) or a reductive annulation product (4‐chromanone) depending on the alkyne substituents.
ChemInform Abstract: An Efficient Approach to the Total Synthesis of Ammosamide B.
Authors: Yang Sheng‐Wei , Wang Chun‐Meng , Tang Kai‐Xiang , Wang Jin‐Xin , Sun Li‐Ping
Published: June 2016

A new three‐step strategy for constructing the key pyrroloquinoline skeleton is developed.
ChemInform Abstract: Cyano Group Removal from Cyano‐Promoted Aza‐Diels—Alder Adducts: Synthesis and Structure—Activity Relationship of Phenanthroindolizidines and Phenanthroquinolizidines.
Authors: Chang Chi‐Fen , Li Chien‐Fu , Tsai Chia‐Chen , Chuang Ta‐Hsien
Published: June 2016

Compounds (IV) show anticancer activity.
ChemInform Abstract: Reinvestigation of the Branimycin Stereochemistry at Position 17‐C.
Authors: Cikos Ana , Triballeau Nicolas , Hubbard Paul A. , Ziher Dinko , Stouten Pieter F. W. , Doyon Julien G. P.‐O. , Deschrijver Tiny , Wouters Johan , Lepine Renaud H. M. , Saniere Laurent
Published: June 2016

The absolute configuration of branimycin (I) is determined by single‐crystal XRD analysis leading to the revision of the formerly proposed stereochemistry of the 1‐hydroxy‐2‐methoxyethyl group.
ChemInform Abstract: Isolation of Toxic Compounds from Wild Phaeocystis globosa.
Authors: Long Chao , Luo Wan‐Ci , Zhou He‐Ying , Shi Yu‐Feng , Gao Cheng‐Hai , Huang Ri‐Ming
Published: June 2016

Two new compounds, namely taenialactam C (I) and globorin A (II) are isolated together with six known compounds.
ChemInform Abstract: Recent Advances in Inorganic Heterogeneous Electrocatalysts for Reduction of Carbon Dioxide
Authors: Zhu Dong Dong , Liu Jin Long , Qiao Shi Zhang
Published: June 2016

Review: 210 refs.
ChemInform Abstract: Recent Developments in the Snthesis of Chiral Compounds with Quaternary Centers by Organocatalytic Cascade Reactions
Authors: Tian Li , Luo Yong‐Chun , Hu Xiu‐Qin , Xu Peng‐Fei
Published: June 2016

Review: [83 refs.
ChemInform Abstract: Defect‐Induced Ferromagnetism in Semiconductors: A Controllable Approach by Particle Irradiation
Authors: Zhou Shengqiang
Published: June 2016

Review: 56 refs.
ChemInform Abstract: The Photodegradation of Polybrominated Diphenyl Ethers (PBDEs) in Various Environmental Matrices: Kinetics and Mechanisms
Authors: Pan Yanheng , Tsang Daniel C. W. , Wang Yingying , Li Yao , Yang Xin
Published: June 2016

Review: 126 refs.
ChemInform Abstract: Studies on the Precise Chemical Synthesis of Human Glycoproteins
Authors: Kajihara Yasuhiro
Published: June 2016

Review: 52 refs.
ChemInform Abstract: Organic Semiconductors Based on Dyes and Color Pigments
Authors: Gsaenger Marcel , Bialas David , Huang Lizhen , Stolte Matthias , Wuerthner Frank
Published: June 2016

Review: [156 refs.
ChemInform Abstract: Role of Functionalization: Strategies to Explore Potential Nano‐Bio Applications of Magnetic Nanoparticles
Authors: Bohara Raghvendra A. , Thorat Nanasaheb D. , Pawar Shivaji H.
Published: June 2016

Review: 209 refs.
ChemInform Abstract: Functional Dendritic Compounds: Potential Prospective Candidates for Dental Restorative Materials and in situ Re‐Mineralization of Human Tooth Enamel
Authors: Jaymand Mehdi , Lotfi Meherdad , Lotfi Rana
Published: June 2016

Review: 132 refs.
ChemInform Abstract: Giant Flexibility of Crystallized Organic—Inorganic Porous Solids: Facts, Reasons, Effects and Applications
Authors: Ferey Gerard
Published: June 2016

Review: 117 refs.
ChemInform Abstract: A Design Concept of Amphiphilic Molecules for Directing Hierarchical Porous Zeolite
Authors: Xu Dongdong , Che Shunai , Terasaki Osamu
Published: June 2016

Review: 107 refs.
ChemInform Abstract: The Effect of Functional Groups in Bio‐Derived Fuel Candidates
Authors: Jenkins Rhodri W. , Moore Cameron M. , Semelsberger Troy A. , Chuck Christopher J. , Gordon John C. , Sutton Andrew D.
Published: June 2016

Review: [43 refs.
ChemInform Abstract: Biogeochemical Transformations of Mercury in Solid Waste Landfills and Pathways for Release
Authors: Lee Sung‐Woo , Lowry Gregory V. , Hsu‐Kim Heileen
Published: June 2016

Review: 143 refs.
AN INSAR PERFORMANCE EVALUATION METHOD BASED ON VIRTUAL PROMINENT SCATTERERS
Authors: An‐Xi YU , Qing‐Song WANG , Zhi‐Yong MENG , Zhen DONG
Published: June 2016

An improved interferometric synthetic aperture radar (InSAR) performance evaluation method based on prominent scatterers (PS) is proposed to precisely assess the accuracies of the absolute/relative interferometric phase and the absolute/relative height. The critical technical defect of the conventional PS‐based method is analysed, where overvalued performance indexes are caused by higher coherence on the PS than on the ordinary ground scene. Virtual prominent scatterers (VPS) around the actual PS are introduced and treated as statistical samples when the indexes are computed. The pixel location of the VPS is estimated indirectly by utilizing the high signal to clutter ratio of the VPS and the accurate relative location between the PS and the VPS. A spaceborne InSAR signal simulation experiment is carried out to validate the new VPS‐based method. The developed method can support performance analysis, error isolation and troubleshooting in InSAR systems.
NOISE SUPPRESSION OF RECEIVER FUNCTIONS USING CURVELET TRANSFORM
Authors: Shao‐Hua QI , Qi‐Yuan LIU , Jiu‐Hui CHEN , Biao GUO
Published: June 2016

Suppressing the scattering induced by the laterally heterogeneous media is important for imaging the crustal structure and its anisotropy from Receiver Functions (RFs) based on the laterally stratified model. Although the scattering can be suppressed, to some degree, with stacking technique or low‐pass filtering, these may lead to undesired waveform distortion, information loss or resolution reduction. To avoid these problems, we make use of the curvelet transform technique, which is developing rapidly in recent years, to reduce the scattering field in the RFs. Unlike exploration seismology, our major challenge comes from the spatially nonuniform sampling of RFs, caused by the spatially incomplete and uneven distribution of stations and events. To overcome these difficulties, we combine the compressed sensing theory with the curvelet‐based denoising method to realize the denoising and wavefield reconstruction, simultaneously. To verify our idea, we have tested the denoising and wavefield reconstruction with synthetic RFs and then apply our method to the observed data at one of the IRIS GSN stations and the western Sichuan array, respectively. The results show that: 1) our method is efficient in suppressing the scattering induced by the lateral heterogeneity of the crust, which leads to great improvement of the signal‐to‐noise ratio and spatial traceability of the RFs. This is valuable for the waveform imaging of the crustal structure and anisotropic parameters from the RFs; 2) the missing data caused by the event distribution can be correctly reconstructed; 3) our method can be applied to either single station or seismic array observations, but it is more efficient in single station observation than the seismic array study.
ANALYSIS AND PROCESSING OF ABNORMAL OBS DATA IN THE SOUTH CHINA SEA
Authors: Qiang WANG , Xue‐Lin QIU , Ming‐Hui ZHAO , Hai‐Bo HUANG , Wei AO
Published: June 2016

Processing and analysis of ocean bottom seismometer (OBS) data are of great importance to obtain the deep crustal structure. The deep seismic profile OBS2006‐2 was carried out in 2006 along the extinct spreading ridge of the northwest sub‐basin of the South China Sea. This survey is successful to provide high quality data whose seismic signals can be observed at the offset up to 120 km, but 2 OBSs’ recording data (OBS03 and OBS06) cannot be read correctly and were not used in later structure modeling. However, OBS data are very precious due to the high cost and arduous work. The price is more expensive when encountering severe weather during a survey. This paper is focused on reprocessing of these 2 OBSs’ data by use of the methods of checking data format, comparing signals with adjacent OBSs and resampling the data. Finally we acquire these 2 OBSs’ seismic record sections in which abundant seismic phases are clearly seen. We also obtain the seismic record section of OBS03 along the profile OBS973‐3 in the Nansha Island using the same methods above. The instrument OBS06 along the profile OBS2006‐2 and the instrument OBS03 along the profile OBS973‐3 are the same instrument confirmed by checking their logs recorded in 2006 and 2011, respectively. It demonstrates that the processing method for abnormal OBS data is reliable and effective. Then the ray‐tracing and travel‐time simulation were carried out for OBS06 and OBS03 using the interactive trial‐and‐error 2D ray‐tracing method based on the previous P‐wave velocity model of OBS2006‐2. The input of new travel‐time picks should provide stricter constraints for the deep structure beneath the profile OBS2006‐2. This research on abnormal data reprocessing does not only improve the reliability and resolution of the crustal structure, but also provide valuable experiences for OBS processing for other study areas in the future.
CHANNEL ANALYSIS OF EM‐MWD BASED ON NMM
Authors: Ye‐Huo FAN , Wei LI , Zai‐Ping NIE , Zhi‐Qiang YANG , Xiang‐Yang SUN
Published: June 2016

In this paper, a theoretical model of EM‐MWD is set up based on the numerical mode matching method (NMM) and source equivalent principle. The model may consider radial and axial inhomogeneities, facilitate analysis of the influence of casing, mud, high conductivity layer, high resistivity layer on signal transmission. The correctness of this theoretical model is proved by calculation and field test. The effect of formation resistivity, working frequency, casing, drilling mud, pillar, high conductivity layer and high resistivity layer on the signal transmission is analyzed.
The effect of superparamagnetic iron oxide nanoparticles surface engineering on relaxivity of magnetoliposome
Authors: Khaleghi Sepideh , Rahbarizadeh Fatemeh , Ahmadvand Davoud , Malek Mahrooz , Madaah Hosseini Hamid Reza
Published: June 2016

The purpose of this work is evaluating the effect of ultra small superparamagnetic iron oxide nanoparticles (USPIONs) coatings on encapsulation efficiency in liposomes and cellular cytotoxicity assay. Moreover, we assessed the effects of surface engineering on the relaxivity of magnetoliposome nanoparticles in order to create a targeted reagent for the intelligent diagnosis of cancers by MRI. For estimating the effect of nanoparticle coatings on encapsulation, several kinds of USPIONs coated by dextran, PEG5000 and citrate were used. All kinds of samples are monodispersed and below 100 ± 10 nm and the coatings of USPIONs have no significant effect on magnetoliposome diameter. The coating of USPIONs could have effect on percentage of encapsulation. The dextran coated USPIONs have more stability and quality accordingly the encapsulation increased up to 92%, then the magnetoliposome nano particles have been targeted by Herceptin and anti‐HER2 VHH, separately. Over storage period of four weeks the resulting particles were stable and physico‐chemical properties such as size and zetapotential did not show any significant changes. The relaxivity of contrast agents was measured using a 1.5 T MRI. The r2/r1 ratio was more than two for all samples which demonstrate the negative contrast enhancing of all SPION embedded specimens. The high ratio of r2/r1 as well as high r2 is the best combination of a negative contrast agent as it is obtained for pure magnetite. The value of r2/r1 for all other samples including Herceptin targeted magnetoliposome, anti‐HER2 VHH targeted magnetoliposome and non‐targeted magnetoliposome were between ~21 to ~28, which show the magnetite embedded samples have enough negative contrast to be detectable by MRI. Therefore the HER2 targeted magnetoliposomes are a good and stable candidate as contrast agents in clinical radiology and biomedical research with minimal cytotoxicity and biocompatibility effects. Copyright © 2016 John Wiley & Sons, Ltd.
Anion‐Directed Entangling Coordination Networks: Luminescence Sensing and Magnetic Properties
Authors: Li Cheng‐Peng , Chen Qi , Mu Yu‐Hai , Du Miao
Published: June 2016

Solvothermal reactions of a bifunctional ligand 4‐(2‐ethyl‐1H‐imidazol‐1‐yl)benzoic acid (2‐Heiba) with Cu(NO3)2 and Cu(OAc)2 afforded two coordination polymers, [Cu3(2‐eiba)4(NO3)2]⋅5 DMF (1; DMF= N,N‐dimethylformamide) and [Cu(2‐eiba)2] (2), respectively, which show a twofold interpenetrated 3D network and 2D+2D→3D polycatenated architecture. Complex 1 is a potential luminescent detector for nitrobenzene and FeIII ions, whereby strong antiferromagnetic interactions are also found between the CuII centers.
Influences of ethanol on the thermodynamics and kinetics in the crystallization of xylitol
Authors: Hartwig Anne , Ulrich Joachim
Published: June 2016

The metastable zone and crystal growth rates of xylitol in water were investigated under the influence of small volume fractions of ethanol. The utilization of low amounts of ethanol is necessary to help adding slightly soluble ingredients during the fabrication of xylitol products, e.g. in food industry. Therefore, the metastable zone and crystal growth rates were determined by means of an ultrasound measurement technique and batch crystallization experiments. It can clearly be seen that the addition of ethanol is lowering the solubility of xylitol in water. The higher the volume fraction of ethanol, the lower the solubility. The metastable zone width is increased whereas the smallest investigated ethanol content results in the widest metastable zone. The crystal growth of xylitol is inhibited by the addition of ethanol whereby the crystal growth rates are decreasing with increasing ethanol content.
Optimal switching Lyapunov‐based control of power electronic converters
Authors: Yfoulis Christos , Giaouris Damian , Ziogou Chrysovalantou , Stergiopoulos Fotis , Voutetakis Spiros , Papadopoulou Simira
Published: June 2016

This paper presents new ideas and insights towards a novel optimal control approach for power electronic converters. The so‐called stabilizing or Lyapunov‐based control paradigm is adopted, which is well known in the area of energy‐based control of power electronic converters, in which the control law takes a nonlinear state‐feedback form parameterized by a positive scalar λ. The first contribution is the extension to an optimal Lyapunov‐based control paradigm involving the specification of the optimal value for the parameter λ in a typical optimal control setting. The second contribution is the extension to more flexible optimal switching‐gain control laws, where the optimal switching surfaces are parameterized by a number of positive scalars λj. Systematic derivation of gradient information to apply gradient‐descent algorithms is provided. The proposed techniques are numerically evaluated using the exact switched model of a DC–DC boost converter. Copyright © 2016 John Wiley & Sons, Ltd.
Maternal deprivation alters growth, food intake, and neuropeptide Y in the hypothalamus of adolescent male and female rats
Authors: Wertheimer Guilherme Soares de Oliveira , Girardi Carlos Eduardo Neves , de Oliveira Alexandra de Sousa Miragaia , Monteiro Longo Beatriz , Suchecki Deborah
Published: June 2016

Maternal deprivation (MD) for 24 hr during the neonatal period impairs body weight gain in adolescent and adult rats. It has been previously shown that maternally deprived rats consume less standard and carbohydrate‐rich diets. Because neuropeptide Y (NPY) is implicated in feeding behavior, we assessed, prospectively, the effects of maternal deprivation, imposed on postnatal days (PND) 3 (DEP3) or 11 (DEP11), on physical development (snout‐anal length and body weight gain, measured once a week) and food intake (assessed daily, during the rest and active phases, from PND 23 to PND 51); NPY‐immunoreactivity (NPY‐ir) in the arcuate nucleus of the hypothalamus was evaluated in male (at PND 52) and female rats in estrous (at PND 53–60). DEP3 and DEP11 male and female adolescents were smaller, lighter, and ate less during the active phase, than their CTL counterparts. This change in food intake was accompanied by reduced NPY‐ir in the arcuate nucleus of the hypothalamus. The present results indicate that maternal deprivation had a negative impact on the physical development and feeding behavior of adolescent rats that may be explained by reduced hypothalamic NPY production.
Take 3 simple steps to avoid litigation, high legal costs
Authors: Charmatz Marc
Published: June 2016

How can your institution avoid litigation under the Americans with Disabilities Act and/or Section 504 of the Rehabilitation Act, or at the very least avoid exposure to high damages and attorney's fees awards? Three simple steps will eliminate and/or reduce costs — engage in the interactive process; hire an ADA/Section 504 coordinator; and, if your college or university is sued, go for early mediation.
Support medical students with psychological disabilities
Authors: Murray Joseph F. , Meeks Lisa M.
Published: June 2016

Medical school is hard for everyone, but it is especially difficult for students with psychological disabilities. In a 2008 study, Lotte Dyrbye and colleagues found that burnout affects up to 50 percent of medical students and that 10 percent of students had experienced suicidal ideation within the past year. The suicide rate among medical students is higher than among the age‐matched population, as are rates of depression. The unique qualities of medical school — and the age of the average medical student — may result in worsening mental health and well‐being.
Understand the do's and don'ts of interviewing for professional jobs
Authors: Hodges Dawn Z.
Published: June 2016

Over the span of my career, I have conducted literally thousands of interviews. I continue to be amazed by what people who are professed professionals still do not know about interviewing for professional‐level jobs. I interview most often for faculty, deans, department chairs, directors of academic units, and other vice president–level positions. Needless to say, the people I interview ought to know how to conduct themselves in an interview. I have found, often enough, that is an assumption on my part. So I hope you won't take offense to my do's and don'ts of interviewing for a professional job in higher education. It appears to be needed by more than a few.
Ten‐year responses of ground‐dwelling spiders to retention harvest in the boreal forest
Authors: Pinzon Jaime , Spence John R. , Langor David W. , Shorthouse David P.
Published: June 2016

The Ecosystem Management Emulating Natural Disturbances (EMEND) project tests the hypothesis that varying levels of green tree retention maintain and retain forest biodiversity better than conventional clear‐cutting. We studied epigaeic spiders to assess biodiversity changes 2, 5, and 10 yr following a range of partial retention harvests (clear‐cut, 10–75% retention) and unharvested controls in four boreal mixedwood cover types. A total of 56 371 adult spiders representing 220 species was collected using pitfall traps. Lasting effects on forest structure were proportional to harvest intensity. These changes strongly influenced spider richness, abundance, and species composition, as well as assemblage recovery. Distinctive assemblages were associated with disturbance level, especially with partial harvests (≤50% retention), and these were dominated by open‐habitat species even 10 yr after harvest. Assemblages were more similar to those of controls in the highest (75%) retention treatment, but significant recovery toward the structure of pre‐disturbance assemblages was not detected for any prescription in any cover type. Although early responses to retention harvest suggested positive effects on spider assemblages, these are better explained as lag effects after harvest because assemblages were less similar to those of unharvested controls 5 yr post‐harvest, and only minor recovery was observed 10 yr following harvest. Retention of forest biodiversity decreased over time, especially in conifer stands and the lower (10–50%) retention treatments. Overall, retention harvests retained biodiversity and promoted landscape heterogeneity somewhat better than clear‐cutting; however, there was a clear gradient of response and no retention “threshold” for conservation can be recommended on the basis of our data. Furthermore, results suggest that retention harvest prescriptions should be adjusted for cover type. We show that low retention ameliorated impacts in broadleaved forests characteristic of earlier stages in mixedwood succession, but only higher retention was associated with less impact in successionally older conifer forests. Although these short‐term responses (10 yr) of spider assemblages support use of retention harvests, understanding the true conservation merit of these practices, relative to conventional approaches, requires evaluation over longer time scales, with work more focused on recovery of biodiversity than on its preservation after harvest.
A Facile “Green” Route for Scalable Batch Production and Continuous Synthesis of Zirconium MOFs
Authors: Reinsch Helge , Waitschat Steve , Chavan Sachin M. , Lillerud Karl Petter , Stock Norbert
Published: June 2016

Considering the requirements for the commercial production of metal–organic frameworks (MOFs), we investigated the aqueous synthesis of zirconium MOFs. A highly versatile route was identified employing ZrOCl2·8H2O, H2O, acetic acid and the respective linker molecule as starting materials. These synthesis conditions are suitable to obtain zirconium MOFs with different topologies like UiO‐66‐(OH)2, zirconium fumarate, zirconium mesaconate, DUT‐67 or MOF‐808 with synthesis times of 1 to 5 h under microwave irradiation. The scalability of the synthesis of zirconium fumarate was demonstrated at multigram scale under reflux conditions using conventional dielectric heating. To ease the recovery of this MOF which bypasses filter paper as a pure product, we identified sodium polyacrylate as a suitable additive to induce aggregation of the particles. Moreover, a custom‐made prototype flow reactor was developed which allows for the continuous synthesis of zirconium fumarate and UiO‐66‐NH2 starting from a slurry of the starting materials. The commonly employed toxic organic solvents needed for activation/purification of the MOFs could be successfully replaced by a basic aqueous solution.
Fabrication of Fast and Sensitive Nanostructure Voltammetric Sensor for Determination of Curcumin in the Presence of Vitamin B9 in Food Samples
Authors: Cheraghi Somaye , Taher Mohammad Ali , Karimi‐Maleh Hassan
Published: June 2016

A novel voltammetric sensor was used for the determination of curcumin by using cadmium oxide nanoparticles‐ionic liquid (1,3‐dipropylimidazolium bromide as a binder) modified carbon paste electrode (CdO‐IL‐MCPE). At pH 7.0 as an optimum electrochemical condition, the oxidation signals for curcumin and vitamin B9 are separated at ca. 0.41 and 0.73 V respectively; facilitating fast and sensitive analysis of curcumin in presence of vitamin B9. The oxidation signal of curcumin represented a linear relationship with the concentration of curcumin (R2=0.9981) in the range of 0.2–320.0 µM, with a detection limit of 0.08 µM.
Determining CLOU Reaction Kinetics for Combined Oxygen Carriers—Discussing the Experimental Methods
Authors: Leion Henrik , Zhan Xiang , Frick Volkmar
Published: June 2016

Combined oxides, primarily manganese based, have shown great potential as oxygen carriers, as they often have oxygen uncoupling properties at relevant temperatures. These oxygen carriers could be a good alternative to copper‐based materials. But in order to scale up or model the chemical‐looping with oxygen uncoupling (CLOU) process reliable oxygen carrier kinetics is needed. The general approach to determine oxygen carrier kinetics is to use thermogravimetric analysis (TGA). However, due to the nature of combined oxygen carriers the conventional approach might not be possible. The objective of this work is to explain and point out the limitations of the conventional way of using TGA for CLOU kinetics. Experiments from three different oxygen carriers, a perovskite, a manganese ore, and a manganese‐silica oxide, are used in order to illustrate the difficulties and spur new thinking in the field.
Monoterpenoid-based preparations in beehives affect learning, memory, and gene expression in the bee brain
Authors: Bonnafé Elsa , Alayrangues Julie , Hotier Lucie , Massou Isabelle , Renom Allan , Souesme Guillaume , Marty Pierre , Allaoua Marion , Treilhou Michel , Armengaud Catherine
Published: June 2016

Bees are exposed in their environment to contaminants that can weaken the colony and contribute to bee declines. Monoterpenoid-based preparations can be introduced into hives to control the parasitic mite Varroa destructor. The long-term effects of monoterpenoids are poorly investigated. Olfactory conditioning of the proboscis extension reflex (PER) has been used to evaluate the impact of stressors on cognitive functions of the honeybee such as learning and memory. The authors tested the PER to odorants on bees after exposure to monoterpenoids in hives. Octopamine receptors, transient receptor potential–like (TRPL), and γ-aminobutyric acid channels are thought to play a critical role in the memory of food experience. Gene expression levels of Amoa1, Rdl, and trpl were evaluated in parallel in the bee brain because these genes code for the cellular targets of monoterpenoids and some pesticides and neural circuits of memory require their expression. The miticide impaired the PER to odors in the 3 wk following treatment. Short-term and long-term olfactory memories were improved months after introduction of the monoterpenoids into the beehives. Chronic exposure to the miticide had significant effects on Amoa1, Rdl, and trpl gene expressions and modified seasonal changes in the expression of these genes in the brain. The decrease of expression of these genes in winter could partly explain the improvement of memory. The present study has led to new insights into alternative treatments, especially on their effects on memory and expression of selected genes involved in this cognitive function. Environ Toxicol Chem 2017;36:337–345. © 2016 SETAC