bluuebunny/crossref_metadata_2025 huggingface dataset:
Open Economy Neoclassical Growth Models and the Role of Life Expectancy
Authors: Tserenkhuu Tselmuun , Kosempel Stephen
Published: August 2023

This paper applies the Ramsey–Cass–Koopmans (RCK) growth model to an open economy so that, when calibrated with standard parameter values that are commonly used in the small open economy macroeconomic literature, the time paths of the model variables and the speeds of convergence implied by the model conform with empirical evidence. Open-economy versions of the RCK growth model lead to several counterfactual conclusions including: infinite speeds of convergence for physical capital and output; and unbalanced consumption and asset growth. We avoid these undesired results by extending the baseline model with human capital, international credit constraints, and finite horizons. Given its finite-horizons feature, our model allows us to study the growth implications of changes in life expectancy from the perspective of an open economy, as most of the existing theoretical-quantitative literature that focus on the relationship assumes a closed economy. The model predicts that increased life expectancy has positive but diminishing marginal effect on long-run output per capita. We find that, between 1960 and 2018, improvements in average life expectancy at birth raised long-run output per capita in sub-Saharan Africa, the OECD region, and Canada by an estimated 57.49 %, 14.94 %, and 11.58 %, respectively. In addition, if average life expectancy at birth in sub-Saharan African countries converges from its current level to the level in their OECD counterparts, the region’s long-run output per capita will increase by an estimated 22.89 %.
Application and teaching of computer molecular simulation embedded technology and artificial intelligence in drug research and development
Authors: Chen Xiaoling , Zhang Junmin , Zhao Quanyi , Ding Li , Wu Zhengrong , Jia Zhong , He Dian
Published: August 2023

With the continuous development of the pharmaceutical industry, people have always paid attention to the safety and effectiveness of drugs, including innovative drugs and generic drugs. For pharmaceutical companies as manufacturers, drug development is a very lengthy process that requires high costs, millions of man-hours, thousands of trials, and the mobilization of hundreds of researchers. Therefore, efforts need to be made to develop drugs with high safety and effectiveness. Drug research and development plays an important role today. Based on this, this article applied computer molecular simulation embedded technology and artificial intelligence technology to drug research and development. First, the problems faced in the research and development of anti-inflammatory disease-dependent tumor drugs were introduced, and then the applications of computer molecular simulation embedded technology and artificial intelligence technology in drug research and development were analyzed. Subsequently, the application of artificial intelligence in drug research and development teaching was analyzed, and a teaching system based on computer molecular simulation embedded technology and artificial intelligence was designed. Finally, the application effects of computer molecular simulation embedded technology and artificial intelligence technology were analyzed, and a feasible conclusion was drawn. The use of computer molecular simulation embedded technology and artificial intelligence technology can greatly improve the efficiency of drug research and development, and the research and development safety of imatinib mesylate has been improved by 7%. On the other hand, it can improve students’ learning interest and stimulate their learning interest, and students’ drug research and development capabilities have been improved. Drug research and development for inflammatory-dependent tumors has good application prospects.
Improving protection of compensated transmission line using IoT enabled adaptive auto reclosing scheme
Authors: Konda Deepthi , Patel Ujjaval , Rathi Ronak , Shah Jaynil , Chothani Nilesh
Published: August 2023

Protection of critical components in the power sector especially the transmission line system is very important to minimize loss of revenue, resources, and productivity. Improvement of power transfer capacity and voltage profile in smart the power grid is achieved by Series Compensation (SC). However, it poses many serious issues in the protection of compensated transmission lines. The majority of faults occurring in transmission lines are transient in nature for which service continuity can be regained by an auto-reclosing scheme. An efficient auto-reclosing scheme that can provide adaptive protection with reliable operation is required to prevent transient and permanent faults in the series compensated transmission line (SCTL). This work highlights the emulation of an Internet of Things (IoT) aided adaptive auto-reclosing scheme in association with an ESP32 controller that provides adaptive dead time control. The reclosing instance has been identified by means of a synchro-check relay. A real-time IoT-aided auto-reclosing scheme has been realized using the ESP32 controller that can generate a trip/reclosing signal instantaneously using the concepts of edge computing. The projected system has been also corroborated by simulating the modeled smart power grid network with wide variations in fault context in PSCAD. The validation of the set of rules is done in MATLAB software for the proposed auto-reclosing scheme. The extracted test outcomes of the simulation and its laboratory hardware implementation indicate an appreciable reduction in dead time which reflects the efficacy of the developed protection scheme.
Determination of a gravimetric geoid model for Eastern Province in the Kingdom of Saudi Arabia
Authors: Al Shehri Ali , Mogren Saad , Ibrahim Elkhedr , Zaki Ahmed
Published: August 2023

A high-resolution gravimetric geoid model was developed for the Eastern Province Kingdom of Saudi Arabia region. The model was created using various datasets, including 320,434 land gravity measurements, 5442 shipborne marine gravity data, the DTU17 altimetry gravity model, and the XGM2019e global geopotential model. The computation strategy employed for modeling the gravimetric geoid involved the Remove-Compute-Restore method with Residual Terrain Model reduction and the 1D-Fast Fourier Transform approach technique. Geoid heights were determined using the Stokes integral with the Wong-Gore modification. To assess the accuracy of the resulting geoid models, they were compared with 4401 GNSS/Levelling points. The geoid accuracy throughout the entire area is better than 1.6 cm in terms of standard deviation (STD) after fitting.
Crystal structure of 2-amino-4-(2-fluoro-4-(trifluoromethyl)phenyl)-9-methoxy-1,4,5,6-tetrahydrobenzo[h]quinazolin-3-ium chloride, C20H18ClF4N3O
Authors: Li Wen-Xuan , Meng Qing-Guo , Hou Gui-Ge , Liu Yong-Jun , Zhang Meng
Published: August 2023

C20H18ClF4N3O, monoclinic, P21/c (no. 14), a = 9.6123(7) Å, b = 11.8692(7) Å, c = 16.9510(12) Å, β = 104.798(7)∘, V = 1869.8(2) Å3, Z = 4, Rgt
(F) = 0.0444, wRref
(F
2) = 0.1043, T = 293 K.
The marketplace landscape in Santok in the 8th–9th century, NW Poland
Authors: Zamelska-Monczak Kinga , Piotrowski Andrzej , Sydor Paweł
Published: August 2023

The results of archaeological research carried out on the early medieval stronghold in Santok prove that from the 2nd half of the 8th century it functioned in the contact zone between Baltic trade centres and inland, as one of the points in the network of goods exchange. We present the centre in a broader context, not only from the perspective of discovered artefacts but from the natural and ideological elements of the landscape of this place created by the communities inhabiting the Warta and Noteć valleys in the 8th and 9th centuries. The settlement was founded in a convergence of waterways in a way that perfectly uses elements of the topography of the area. Wetlands were important ecological niches for residents whose lifestyle was associated with exploring both the valley and upland zones. Santok is difficult to interpret merely as a mere reflection of the practicality of power or economic activity, including manufacturing and trade. It is a clearly legible place in the landscape, with a symbolic structure that represents the concepts of the cosmological order related to the spatial organization of the exchange point and the communication node. So far Santok is the only recognized trading post on a waterway, in this part of the Slavic region, with such an early chronology. Thus we have attempted to present the landscape of this place, considering its many elements, at different levels of perception and in a broad context.
Sustainable Development Goals and Humanistic Management in Hospitality and Tourism: Systemic Approaches and Application-Oriented Perspectives Using the Example of Family Businesses
Authors: Pillmayer Markus , Obermeyer Nancy J. , Scherle Nicolai , Rundshagen Volker
Published: August 2023

So far, only a minor proportion of businesses – across all economic sectors – has a business model designed to meet the complex requirements of the UN 2030 Agenda. The transformation to a more sustainable economy for the benefit of people and the planet, let alone honouring the principles of Humanistic Management, remains a Herculean task. This article presents family-run companies from the hospitality and tourism industry that have succeeded in aligning their corporate structures, products, and operations with Sustainable Development Goals of the UN 2030 Agenda, building the bridge to –and, in part, explicitly integrating –principles of Humanistic Management. A systemic approach serves as the conceptual-theoretical framework, providing a valuable basis for better understanding the role of individual companies in the complex overall system of the 2030 Agenda. Based on three case studies, presenting findings from expert interviews with selected managing directors or owners of family businesses, it becomes clear that this type of business is particularly well suited to successfully manage the multi-layered challenges of a transformation due to its inherent characteristics.
Fünfzig Jahre „Zeitschrift für germanistische Linguistik“ (ZGL) – Widerspiegelung und Förderung von Wissenschaftsentwicklung
Authors: Fix Ulla
Published: August 2023

The article is devoted to a description of the social-political and scientific-historical conditions before and during the founding of the “Zeitschrift für germanistische Linguistik” and their consequences for the journal. The influence of politics, contemporary history and the history of science on scientific behaviour becomes clear. What promoted the need for such a journal? What demands did it make of itself? What forms of presentation did it find and what topics did it devote itself to? It becomes apparent that ZGL is still a very suitable place to be up to date with current linguistics, i. e. to inform oneself about topics, to deal with them in a constrictive manner and to get to know research areas and representatives of the subject. An overview of the diversity of the subject and the tendencies of its development is made possible. This is the merit of the journal. However, it does not fulfil its self-obligation to the same extent in all areas (e. g. text linguistics, stylistics, discourse linguistics). It was surprising to see that representatives of East German linguistics certainly had a place in the journal. One gets the impression of a certain self-evidence of common discourse.
A importância da utilização de bancos perfis genéticos no Brasil e a preservação da cadeia de custódia
Authors: Pereira Luis
Published: August 2023

Este trabalho tem como objetivo demonstrar como ocorre a coleta e a utilização de dados genéticos relacionados a crimes hediondos no Brasil, a partir da utilização das informações presentes no Banco Nacional de Perfis Genéticos (BNPG) na resolução de crimes, além de ressaltar a importância de uma cadeia de custódia devidamente preservada, o que se caracteriza como elemento fundamental na resolução desses casos. Para isso, foi analisado o processo de desenvolvimento técnico e de adoção do uso de dados genéticos em investigações policiais a níveis nacional e internacional, bem como das técnicas e aparato tecnológico que os envolvem, traçando assim uma linha temporal desde o início do uso dessas informações a nível investigativo até o presente, com a adoção formal desses métodos no Brasil, que teve como marco a Lei 12.654/2012, que instituiu o BNPG, demonstrando assim o caráter interativo das diversas áreas do conhecimento e seu desenvolvimento conforme as necessidades de cada momento histórico.
“Luspatercept: a lifesaving therapy for transfusion-dependent thalassemia patients with alloimmunization complications”
Authors: Delicou Sophia , Nomikou Effrosini , Koskinas Ioannis
Published: August 2023

This case demonstrates the benefits of luspatercept for thalassemic patients who are unable to receive adequate blood transfusions. It acts as a selective ligand trap and inhibits TGF- signaling via Smad2/3 to promote differentiation and maturation of late-stage erythroid precursors. Phase III clinical data showed that a 33% reduction in transfusion burden from baseline was achieved. The administration of luspatercept was a challenge due to the coexistence of antiphospholipid syndrome, portal vein thrombosis and splenectomy. Since initiating luspatercept, the patient has not experienced any adverse events and her general condition has improved.
Fanconi anemia and paroxysmal nocturnal hemoglobinuria, case report
Authors: Raúl Aragón Abrantes Ariel , Hernández Aguiar Danelis , Raúl Medina Martín Alberto
Published: August 2023

Introduction: Fanconi Anemia is a congenital disease associated with defects in the mechanisms of repair of the genetic material that allow to maintain the stability of the human genoma. Paroxysmal Nocturnal Hemoglobinuria is a clonal and acquired disease caused by a somatic mutation in the gene PIG-A. Objective: to present the characteristics of a child with diagnosis of Fanconi Anemia with a Paroxysmal Nocturnal Hemoglobinuria clone. Development: An 8 year-old female infant who come to the consultation for mucosal-skin paleness and purpuric manifestations. After several studies the diagnosis of Fanconi Anemia with Paroxysmal Nocturnal Hemoglobinuria clone was made. Conclusions: patient with a medullary failure congenital and acquired, that given their characteristics require of the bone marrow transplantation like only curative therapy.
Az esztergom-belvárosi kálváriakápolnák és stációk összművészeti jelentősége
Authors: Galántai Zsófia , Prokopp Mária , Zsembery Ákos
Published: August 2023

A hazai századforduló építészetének egyik kiemelkedő emléke az esztergomi belvárosi Kálvária-hegyen található összművészeti együttes, mely két kápolnából és 14 épített stációból áll. A több évtizedes elhanyagoltság után néhány évvel ezelőtt megkezdődhetett az értékek kutatása és mentése, az alsó kápolnát sikerült részben felújítani, ám a felső kápolna ez év elején már az összedőlés határára került. Közösségi és egyházmegyei kezdeményezésre és a város vezetésének segítségével az utolsó pillanatban sikerült megmenteni. A tervezést és felújítást megelőző kutatásaink olyan építészeti és művészettörténeti gazdagságot tárnak elénk, melyek országos szintű értékek, bemutatásuk és védelmük közös feladatunk. A restaurátori kutatások és értékmentések megtörténtek, és megindult a rekonstrukciós munka is. E cikk alapvető célja, hogy a szakma és a közösség megismerhesse, magáénak érezhesse ennek az együttesnek hazánkkal összefonódott sorsát, mely nemcsak közös múltunk tanúja, de közös jövőnk záloga is egyben.
Influence of complex treatment of periodontal tissue diseases on the indices of antioxidant and prooxidant systems in teenagers and young adults
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Lisetska I.S.
Published: August 2023

Purpose - to study the effect of complex treatment of periodontal tissue diseases on the indices of antioxidant and prooxidant systems of oral fluid in adolescents and young adults. Materials and methods. The biochemical parameters of oral fluid before and after treatment were studied in 114 adolescents and young adults (15 to 24 years old), who were divided into groups: the Group I included 26 people who smoked traditional cigarettes; the Group II - 22 people who smoked electronic cigarettes (vapes); the Group III - 23 people who smoked tobacco heating devices (IQOS); the Group IV - 43 people without a smoking habit. The following biochemical parameters were studied: the activity of superoxide dismutase and catalase enzymes, dyne conjugates and products that react to thiobarbituric acid, before and after treatment with the proposed complex: general - Quertin, Supervit and BioGaya ProDentis; topical - Stomolik and Holisal and conventional treatment. Results. In the Group I patients, the activity of superoxide dismutase in the oral fluid decreased by 1.4 times compared to the Group IV patients (p<0.05); in the Group II and III patients - by 1.2 times compared to non-smokers (p<0.05). In the Group I, the activity of the catalase enzyme decreased significantly (2.6 times) compared to the Group IV (p<0.05); in the Group II and III - by 1.8 times compared to non-smokers (p<0.05). The analysis of the data showed that in the Group I, the number of products reacting to thiobarbituric acid increased 2.5 times compared to the Group IV (p<0.05); in the Groups II and III - 1.9 times compared to the Group IV (p<0.05). The amount of diene conjugates in the oral fluid increased in both the Group I and Groups II and III patients, respectively, by 1.4 and 1.2 times compared with the Group IV patients (p<0.05). After treatment, there was an increase in antioxidant defense and inhibition of lipid peroxidation in oral fluid, with better results in the subgroups in which the proposed complex treatment was used, as well as in adolescents and young adults without smoking habits. Conclusions. In teenagers and young adults smokers, there is an increase in lipid peroxidation and a decrease in the antioxidant properties of oral fluid. Comparison of the results of biochemical parameters before and after treatment of periodontal tissue diseases in the observation groups by different methods indicates the advantages of the proposed complex treatment and allows us to conclude that it is highly effective. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author.
Câncer de mama após radioterapia torácica em pacientes jovens: o que o radiologista precisa saber?
Authors: Lago Bianca Miranda , Bello Stella dos Santos , Gondim Guilherme Rocha Melo , Makdissi Fabiana Baroni Alves , Bitencourt Almir Galvão Vieira
Published: August 2023

Resumo Os cânceres secundários induzidos por radiação são complicações raras da radioterapia e geralmente ocorrem na área tratada ou próximo a ela. Mulheres com menos de 30 anos de idade tratadas com radioterapia torácica têm risco significativamente aumentado de desenvolver câncer de mama ao longo da vida, em comparação com a população em geral. Para as pacientes tratadas com irradiação torácica com dose igual ou superior a 10 Gy é recomendado rastreamento anual com mamografia e ressonância magnética iniciando oito anos após o tratamento, desde que este início seja após 25 anos de idade. O tratamento do câncer de mama secundário nessa população deve ser individualizado e discutido com equipe multidisciplinar, para evitar toxicidade relacionada ao tratamento do câncer primário.
Deep infiltrating endometriosis: cine magnetic resonance imaging in the evaluation of uterine contractility
Authors: Soares Deborah Monteiro , Bittencourt Leonardo Kayat , Lopes Flavia Paiva Proença Lobo , Oliveira Marco Aurelio Pinho de
Published: August 2023

Abstract Objective: To evaluate uterine function by using cine magnetic resonance imaging to visualize the contractile movements of the uterus in patients with and without deep infiltrating endometriosis (with or without associated adenomyosis). Materials and Methods: This was a prospective case-control study. The study sample comprised 43 women: 18 in the case group and 25 in the control group. We performed cine magnetic resonance imaging in a 3.0 T scanner, focusing on the presence, direction, and frequency of uterine peristalsis. Results: The frequency of uterine peristalsis was higher in the case group than in the control group, in the periovulatory phase (3.83 vs. 2.44 peristaltic waves in two minutes) and luteal phase (1.20 vs. 0.91 peristaltic waves in two minutes). However, those differences were not statistically significant. There was a significant difference between the patients with adenomyosis and those without in terms of the frequency of peristalsis during the late follicular/periovulatory phase (0.8 vs. 3.18 peristaltic waves in two minutes; p < 0.05). Conclusion: The frequency of uterine peristalsis appears to be higher during the periovulatory and luteal phases in patients with deep infiltrating endometriosis, whereas it appears to be significantly lower during the late follicular/periovulatory phase in patients with adenomyosis. Both of those effects could have a negative impact on sperm transport and on the early stages of fertilization.
Behavior of total alkaline phosphatase after radium-233 therapy in metastatic castration-resistant prostate cancer: a single-center, real-world retrospective study
Authors: Lopes Flávia Paiva Proença Lobo , Pedras Marcos Villela , Ferreira Álida Rosária Silva , Ledesma Patricia Massucheto , Dias Paulo Roberto Telles Pires , Pedras Felipe Villela
Published: August 2023

Abstract Objective: To describe the behavior of total alkaline phosphatase (tALP) in patients with metastatic castration-resistant prostate cancer receiving radium-223 therapy, in a real-world scenario, and to describe overall survival (OS) among such patients. Materials and Methods: This was a retrospective study involving 97 patients treated between February 2017 and September 2020. Patients were stratified by the baseline tALP (normal/elevated). A tALP response was defined as a ≥ 30% reduction from baseline at week 12. For patients with elevated baseline tALP, we also evaluated treatment response as a ≥ 10% reduction in tALP after the first cycle of treatment. We defined OS as the time from the first treatment cycle to the date of death. Results: There was a significant reduction in the median tALP after each cycle of treatment (p < 0.05 for all). Data for tALP at week 12 were available for 71 of the 97 patients. Of those 71 patients, 26 (36.6%) responded. Elevated baseline tALP was observed in 47 patients, of whom 19 (40.4%) showed a response. Longer OS was observed in the patients with normal baseline tALP, in those with elevated baseline tALP that showed a response to treatment (≥ 10% reduction), and in those who received 5-6 cycles of therapy. Conclusion: The tALP may be used to predict which patients will benefit from treatment with a greater number of cycles of radium-223 therapy and will have longer OS.
Evidence of the adverse effects of air pollution on the population’s health in Spain: analysis of the economic costs of premature deaths
Authors: Casal Bruno , Rivera Berta , Currais Luis
Published: August 2023

Abstract: Exposure to ambient air pollution increases mortality and morbidity, leading disabilities, and premature deaths. Air pollution has been identified as a leading cause of global disease burden, especially in low- and middle-income countries in 2015 (Global Burden of Diseases, Injuries and Risk Factors Study, 2015). This study explores the relation between mortality rates and particulate matter (PM) concentrations in the 50 Spanish regions for the period 2002-2017. Moreover, we estimated the premature deaths due to PM in Spain according to welfare and production losses in 2017. Random-effects models were developed to evaluate the relation between mortality rates and PM concentrations. The economic cost of premature deaths was assessed using the Willingness to Pay approach to quantify welfare losses and the Human Capital method to estimate production losses. PM10 concentrations are positively related to mortality due to respiratory diseases and stroke. Based on 10,342 premature deaths in 2017, losses in welfare amount to EUR 36,227 million (3.1% of Spanish GDP). The economic value of current and future production losses reached EUR 229 million (0.02% of GDP). From a social perspective, air pollution is a public health concern that greatly impacts health and quality of life. Results highlight the need to implement or strengthen regulatory, fiscal, and health public policies to substantially benefit the population’s health by reducing their exposure to air pollution.
Perceptions of health professionals in providing care for people with anorexia nervosa and bulimia nervosa: a systematic review and meta-synthesis of qualitative studies
Authors: Maia Bruna Bortolozzi , Campelo Felipe Gonçalves , Rodrigues Elaine Campos Guijarro , Oliveira-Cardoso Érika Arantes , Santos Manoel Antonio dos
Published: August 2023

Abstract: This study sought to synthesize and reinterpret findings from primary qualitative studies on the experience of health professionals in caring for people with anorexia nervosa and bulimia nervosa. We conducted a systematic review of the literature with the SPIDER search strategy assessing six databases. A meta-synthesis was performed with data from qualitative studies. Two independent reviewers screened and assessed the articles, extracted data from the articles and elaborated thematic synthesis. Nineteen articles met the inclusion/exclusion criteria. The meta-synthesis revealed three descriptive themes: Going outside the comfort zone: hard relational experiences of health professionals in providing care for people with anorexia nervosa and bulimia nervosa; Reflecting on treatment: relevance of discussion, communication, and flexibility in health professionals’ work with anorexia nervosa and bulimia nervosa; and Dealing with ambivalences: experiences of health professionals with family members of people with anorexia nervosa and bulimia nervosa. We elaborated two analytical themes: Making work with eating disorders palatable: malleability necessary for health professionals in bonding with people with anorexia and bulimia nervosa and their families; and Leaving the professional comfort zone: transition from multi to interdisciplinary. Thus, mental health professionals who work with people diagnosed with anorexia and bulimia nervosa cope with hard emotional experiences that makes them feel out of their comfort zone, requiring flexibility to benefit a good therapeutic alliance, but there are still difficulties in promoting interdisciplinarity.
Fluxo dos Paresi entre os níveis de atenção à saúde no Distrito Sanitário Especial Indígena de Cuiabá, Mato Grosso
Authors: Cintra Elizângela Vicunã Couto da Silva , Weiss Maria Clara Vieira , Misoczky Maria Ceci Araujo , Bordin Ronaldo
Published: August 2023

RESUMO Estudo de caso que objetivou descrever o fluxo entre os níveis da atenção à saúde dos Paresi, do Distrito Sanitário Especial Indígena de Cuiabá, no Mato Grosso. O fluxo previsto pelo Plano Distrital de Saúde Indígena não considera a organização local de saúde e a articulação entre as instâncias do Sistema Único de Saúde, situação que foi prevista no fluxo estabelecido pelos profissionais de saúde. A estes soma-se o fluxo estabelecido pelos indígenas. Concluiu-se que o fluxo que consta do Plano Distrital de Saúde Indígena é inaplicável; o estabelecido pelos profissionais de saúde prevê aproximação ao real, mas a não-observação da particularidade gera empecilhos para o acesso a outros níveis de atenção.
Probiotic yeast Saccharomyces cerevisiae Az-12 isolated from pomegranate juice presented inhibitory effects against pathogenic bacteria
Authors: Latif A. S. , Saparbekova A. A. , Akhmedova Z. R. , Kaldybekova G. , Daugaliyeva S. T.
Published: August 2023

Abstract The potential probiotic yeast was isolated from the Kyzyl Anor pomegranate variety growing in the Turkestan region (Kazakhstan). The yeast strain was identified as Saccharomyces cerevisiae Az-12. Molecular genetic identification was carried out using the Sanger sequencing method. The degree of homology of the S. cerevisiae Az-12 strain with the strain MH608341.1 Saccharomyces cerevisiae isolate extr03 was 99.65%. Antagonistic effect of the yeast against pathogenic bacteria was confirmed according inhibition zones for Staphylococcus aureus 13.5 ± 0.05 mm; the inhibition zones for Escherichia coli 12.8 ± 0.05 mm; and 10.7 ± 0.05 mm for Pseudomonas aeruginosa. Scanning microscopy of S. cerevisiae Az-12 and S. aureus confirmed the adhesive ability of the yeast cell surface to S. aureus. S. cerevisiae Az-12 were chosen as the most promising, as they are able to quickly ferment juices. Functional drinks containing pomegranate juice and yeast with a probiotic effect can be considered as a useful synbiotic product formulation.
Ecossistema de centro de pesquisa universitária em project studies: Um framework conceitual
Authors: Moutinho José da A. , Rabechini Junior Roque , Fernandes Gabriela
Published: August 2023

Resumo Objetivo: Propor o framework conceitual do ecossistema de um centro de pesquisa universitária em project studies. Trata-se de um ambiente capaz de articular e integrar distintos atores, como acadêmicos e praticantes de organizações públicas e privadas, organizações não governamentais e associações de classes, com o propósito de discutir fronteiras teóricas e empíricas em project studies e produzir conhecimento e tecnologias diretamente aplicáveis às organizações, e assim gerar impacto em nível individual, das organizações e da sociedade. Originalidade/valor: A criação de espaço colaborativo, envolvendo aca-dêmicos e praticantes, para coprodução de conhecimento, tem sido apontada como crítica para impulsionar a área de gestão de projetos. O framework estabelece uma linguagem comum entre acadêmicos e praticantes para potencializar o impacto dos resultados de pesquisas colaborativas em gestão de projetos. Design/metodologia/abordagem: Foi realizada uma revisão sistemática da literatura a partir de uma busca nas bases de dados Scopus e Web of Science, e avaliaram-se 11 frameworks sob a perspectiva de impactos sustentáveis. O framework mais aderente foi identificado, analisado e enriquecido com uma camada adicional dedicada à área de gestão de projetos. Resultados: O framework conceitual proposto é composto por quatro camadas: project studies, elementos processuais (recursos, atividades, resultados diretos, indiretos e impactos), mecanismos organizacionais de suporte e circunstâncias, e contexto. Como estudos futuros, sugerem-se a agregação de dados empíricos à estrutura proposta e a avaliação do framework em um ambiente acadêmico colaborativo.
Reinventando o método de Eratóstenes
Authors: Gomes Tuan M. , Marques Ivo A.
Published: August 2023

No final do século III a.C. o polímata grego Eratóstenes de Cirene realizou a mais célebre estimativa do perímetro da Terra. Para tanto ele se valeu do fato de as cidades de Alexandria e Siena estarem aproximadamente no mesmo meridiano (mesma longitude), bem como do fato de no dia do solstício de verão (no hemisfério norte) o Sol, ao meio-dia, estar a pino em Siena. No presente trabalho generalizamos, de forma aproximada, o método de Eratóstenes para o caso em que as localidades estejam separadas tanto em latitude quanto em longitude. Além disso, no modelo proposto, não é necessário Sol a pino ao meio-dia local em nenhuma das duas cidades. Realizamos três experimentos, ou seja, trabalhamos com três pares de cidades: Goiânia e Juiz de Fora, Goiânia e Maraú e Goiânia e Bragança Paulista. Esperamos que o artigo venha a ser utilizado por professores de Física, Astronomia, Geografia e/ou Matemática.
Física de Partículas no ensino médio Parte II: Física Nuclear
Authors: Guio Thaisa Carneiro da Cunha , Dorsch Gláuber Carvalho
Published: August 2023

Apresentamos a segunda parte de uma série de artigos que propõe uma nova sequência didática sobre Física de Partículas para o ensino médio. O tema do presente trabalho é a Física Nuclear. O objetivo principal da sequência é abordar o assunto de modo a fomentar a alfabetização científica dos(as) estudantes, em uma perspectiva que relaciona Ciência, Tecnologia, Sociedade e Meio Ambiente (CTSA). Avaliamos as potencialidades e a efetividade do material aqui proposto, aliado a uma postura dialógica docente, a partir da análise de indicadores de alfabetização científica e de engajamento dos(as) estudantes durante as intervenções realizadas em uma escola pública estadual do Espírito Santo.
Informação e empoderamento feminino no Instagram: estudo a partir de coletivos feministas
Authors: Viana Anna Raquel de Lemos , Lima Izabel França de , Soares Gilberta Santos
Published: August 2023

Resumo: Considera-se espaço de empoderamento aquele no qual é possível ressignificar, construir e reconstruir representações e identidades atravessadas pelas representações sociais, historicamente engendradas na sociedade. Analisa-se três coletivos de mulheres que atuam em prol de uma sociedade democrática e com igualdade de gênero, com base em novas narrativas, sendo mulheres vinculadas à universidade e ao mercado, sem vínculo estrutural. Objetiva-se analisar como a rede social digital Instagram constituiu um espaço de empoderamento feminino. Para isso, utilizam-se como instrumentos de coleta de dados entrevistas semiestruturadas individuais com mulheres que compunham a coordenação e o gerenciamento dos perfis no Instagram. Para analisar e tratar os dados, optou-se pela Análise do Discurso do Sujeito Coletivo, um método que consiste em resgatar representações sociais significativas presentes. O estudo indicou que o Instagram é compreendido como um lugar de informação e empoderamento. Além disso, os coletivos servem para dar voz à identidade das mulheres como feministas e maximizar suas ações no Instagram, possibilitando um espaço de representação e agenciamento coletivo, no qual utilizam a informação como imperativo para a relação de uma subjetividade política e social com ações de conscientização, promovendo o empoderamento das mulheres.
Bibliotecas universitárias públicas no YouTube: métricas dos canais
Authors: Trevisol Neto Orestes , Cândido Ana Clara , Nascimento Mateus Rebouças , Sena Priscila Machado Borges , Dornelles Dayane
Published: August 2023

Resumo: Analisa as bibliotecas universitárias federais e estaduais no que concerne ao desenvolvimento de novas formas de interação e comunicação com suas comunidades, a partir das métricas de visualização no YouTube. Caracteriza-se como uma pesquisa exploratória e descritiva, de abordagem mista com a aplicação das técnicas de pesquisa bibliográfica e documental. Para a identificação das universidades federais e estaduais brasileiras, recorreu-se a plataforma E-mec, no qual aplicaram-se os seguintes filtros na busca: sendo considerados todas as unidades federativas, selecionando apenas universidades de natureza pública federal e pública estadual, totalizando 110 universidades. Com base nas instituições listadas, foram acessados os sites das universidades e, posteriormente, localizadas as abas que se intitulavam de Biblioteca e ou Sistema de Biblioteca. Na aba das bibliotecas, localizou-se informação sobre redes sociais, tutoriais e canal no YouTube. Quando não localizadas essas informações, pesquisou-se diretamente no YouTube pela abreviatura da universidade, associando como biblioteca ou sistema de biblioteca. Assim foram localizados 57 canais de bibliotecas, sendo delimitados os canais a partir de 1.000 inscritos, restando 14 deles vinculados às 14 universidades. As bibliotecas universitárias da região sul e sudeste consolidam suas práticas e serviços nos canais, e o maior fluxo de publicações e visualizações nos canais corresponderam ao período de distanciamento social, inferindo que as bibliotecas universitárias utilizaram a plataforma como recurso de comunicação. As temáticas recorrentes nos 70 vídeos listados focam o Currículo Lattes, a normalização de trabalhos acadêmicos (citação, referência), o uso de fontes de informação e pesquisa em bases de dados, a utilização dos gerenciadores bibliográficos (Mendeley, EndNote, Zotero), a construção de trabalhos acadêmicos, projeto de pesquisa e artigos científicos (escrita), plágio acadêmico, uso do Canva, Excel, Open Journal Systems.
Lei Geral de Proteção de Dados (LGPD) e repositórios institucionais: reflexões e adequações
Authors: Nascimento Bruna Laís Campos do , Silva Edilene Maria da
Published: August 2023

Resumo: Este artigo discute a Lei Geral de Proteção de Dados no contexto dos repositórios institucionais, enfocando as adequações necessárias a serem realizadas. Apresenta um breve panorama da legislação brasileira que trata sobre a privacidade e a proteção de dados. O presente trabalho caracteriza-se quanto aos fins como uma pesquisa de natureza exploratória, e quanto aos meios como bibliográfica e documental, com abordagem qualitativa. A partir das análises, foi identificado que a Lei Geral de Proteção de Dados apresenta consistentes diretrizes e sanções para que as instituições possam garantir adequados tratamento e segurança dos dados pessoais. Quanto aos repositórios, foi percebido que adaptações são necessárias e o estudo propõe algumas recomendações, principalmente no que concerne aos processos e fluxos de trabalho, à revisão de documentos institucionais, capacitação e às ações de transparência. Conclui que as discussões sobre a privacidade e a proteção dos dados pessoais precisam ser fomentadas na sociedade, incluindo os repositórios nesse cenário de aplicação.
Parâmetros sensoriais e instrumentais de sobremesas lácteas sabor chocolate obtidas no mercado varejista
Authors: Cutrim Camila Sampaio , Torres Fernanda Romano , Cortez Marco Antonio Sloboda
Published: August 2023

Resumo A indústria alimentícia tem apresentado uma grande diversificação de produtos com diferentes sabores, consistências e públicos-alvo. Sobretudo o ramo das sobremesas lácteas apresenta uma vasta gama de produtos com base láctea ou de seus derivados. As sobremesas lácteas sabor chocolate são um dos tipos de sobremesas comerciais mais comuns no Brasil. Nesse contexto, o objetivo deste trabalho foi avaliar atributos sensoriais e instrumentais de sobremesas lácteas achocolatadas disponíveis no mercado local. Cinco marcas de sobremesas lácteas comerciais disponíveis nos mercados de varejo foram avaliadas quanto à cor instrumental, viscosidade aparente e atributos sensoriais para determinar como isso afeta a percepção dos consumidores, usando a Análise de Penalidades e a Análise Hierárquica de Agrupamento. Observou-se falta de uniformidade entre as amostras analisadas, fato que se confirma do ponto de vista sensorial já que entre as opiniões dos consumidores, para a maioria dos atributos, as amostras foram consideradas acima ou abaixo do ideal e que os parâmetros de impressão global, cor e sabor foram os atributos mais significativos que podem influenciar positivamente na decisão de compra. Podemos concluir que os atributos das análises sensorial e instrumental podem ser uma ferramenta importante para a indústria de alimentos para determinar os pontos fracos dos produtos e os desejos dos consumidores-alvo.
Effect of emulsifier addition on metabolizable energy reduction in broiler diets
Authors: Oliveira Marcus Vinícius Garcia de , Leandro Nadja Susana Mogyca , Café Marcos Barcellos , Santos Raphael Rodrigues dos , Jacob David Vanni , Pires Marília Ferreira
Published: August 2023

Abstract This study aimed to evaluate the effect of including soy lecithin emulsifier (SL) in broiler diets with reduced metabolizable energy levels and to correlate it with nutrient metabolizability coefficients, as well as to determine apparent metabolizable energy (AME). Two metabolic trials were conducted in a completely randomized design with a 3x2 factorial arrangement (diet with three levels of metabolizable energy, with or without the inclusion of emulsifier), totaling six treatments. In the starter phase, chicks received diets with 2,950, 3,050, and 3,150 kcal/kg of metabolizable energy, with six replications of 10 birds each, totaling 360 birds. In the grower phase, the energy levels of 3,100, 3,150, and 3,200 kcal/kg of feed were tested in 210 birds were used in seven replications of five chicks each. An interaction effect was observed in the starter phase, with the nitrogen metabolizability coefficient increasing when the emulsifier was added to diets with reduced energy. Additionally, emulsifier inclusion increased nitrogen-corrected AME (AMEn). An interaction effect was also present in the grower phase, with AME and AMEn increasing when the emulsifier was added to diets with lower energy levels. In summary, emulsifier inclusion in broiler diets can reduce metabolizable energy while improving AMEn in both the starter and grower phases, as well as AME in growing broilers.
GUIDELINES FOR THE SELF-MANAGEMENT OF PEOPLE SUBJECTED TO HEMATOPOIETIC STEM CELL TRANSPLANTATIONS
Authors: Mendes Poliana Novais , Chagas Marléa Crescêncio , Dutra Herica Silva , Duarte Sabrina da Costa Machado , Farah Beatriz Francisco , Mateus Gleiziany dos Santos , Sanhudo Nádia Fontoura
Published: August 2023

ABSTRACT Objective: to know meanings and demands for the self-management of home-based care for Hematopoietic Stem Cell transplant recipients and to discuss these demands with nurses, aiming at proposing guidelines. Method: a qualitative study based on the convergent care research study developed between December 2020 and August 2021 in a Hematopoietic Stem Cell Transplantation Service from Juiz de Fora - Minas Gerais, carried out in two stages: semi-structured interview and small group discussion. 17 people participated in the study: 12 transplanted individuals and five nurses. Data analysis was supported by the Iramuteq software and by the synthesis and theorization proposed by convergent care research. Results: in Stage 1, performed with transplanted patients, six classes emerged that were interpreted in four subcorpuses and pointed out the meanings and demands for self-management. In Stage 2, performed with nurses, the demands found in Stage 1 were submitted to reflection in the discussion group and ratified. Based on the findings, the guidelines to meet the health self-management demands of transplanted people were as follows: professional monitoring, adherence to the treatment, maintenance of the prescribed care measures, search for guidelines and information, implications of the diagnosis, restoration of immunity, inclusion in the job market, physical limitations, and changes in everyday habits. Conclusion: the guidelines proposed reflect the understanding of the needs experienced for an individual to adapt to the health/disease process in the post-Hematopoietic Stem Cell Transplantation phase, and express the importance of carrying out strategies that promote self-management.
Factors associated with frailty in older users of Primary Health Care services from a city in the Brazilian Amazon
Authors: Bezerra Polyana Caroline de Lima , Rocha Bruna Lima da , Monteiro Gina Torres Rego
Published: August 2023

Abstract Objective To estimate the prevalence of frailty syndrome and its association with socioeconomic, demographic and health variables, in elderly people treated at two Health Units in the city of Rio Branco, Acre, from October 2016 to June 2017. Method The prevalence of frailty was measured using the Edmonton Frail Scale (EFS), and associations were tested with selected variables. Poisson regression, with robust variance and 95% confidence intervals, was used to estimate the prevalence ratios and define the adjusted model. All analyzes took into account the sample weights and were performed using SPSS version 20. Results It was found that 35.1% of the sample showed fragility. The prevalence of frailty was associated with being 75 years old or more, physical inactivity, nutritional risk, cognitive deficit, negative health perception, using 5 or more medications and having/history of cancer, falls in past year, living alone, unsatisfactory neighborhood safety and being of ethnicity/non-white color. Conclusion The alert profile for screening for frailty was verified, which may assist in the clinical practice of FHS professionals in the study population, and also considers the need to implement and strengthen eldely's health care programs and performance of the Family Health Support Centers.
Fatores associados à fragilidade em pessoas idosas usuárias de serviços de Atenção Primária à Saúde de uma capital da Amazônia Brasileira
Authors: Bezerra Polyana Caroline de Lima , Rocha Bruna Lima da , Monteiro Gina Torres Rego
Published: August 2023

Resumo Objetivo Estimar a prevalência da síndrome de fragilidade e sua associação com variáveis socioeconômicas, demográficas e de saúde, em idosos atendidos em duas Unidades de Saúde (US) no município de Rio Branco, Acre, no período de outubro de 2016 a junho de 2017. Método A prevalência de síndrome de fragilidade foi medida pela Edmonton Frail Scale (EFS), investigada em uma amostra calculada de 298 pessoas idosas, selecionadas aleatoriamente por meio de sorteio. Utilizou-se a Regressão de Poisson, com variância robusta e intervalos de confiança de 95%, para estimar as razões de prevalência e definir o modelo ajustado. Todas as análises levaram em consideração os pesos. Resultados Verificou-se que 35,1% da amostra apresentou fragilidade. A prevalência de fragilidade foi associada a ter 75 anos ou mais, inatividade física, risco nutricional, deficit cognitivo, percepção negativa da saúde, usar 5 ou mais medicamentos e ter/histórico de câncer, queda no último ano, morar sozinho, segurança de bairro insatisfatória e ser da etnia/cor não branca. Conclusão Verificou-se o perfil de alerta para rastreio da fragilidade, que poderá auxiliar na prática clínica dos profissionais das US da população de estudo e, ainda, considera a necessidade de implantação e fortalecimento de programas de atenção à saúde da pessoa idosa e atuação de matriciamento e/ou grupos de apoio multiprofissional à Saúde da Família.
Cervical human papillomavirus infection in older women
Authors: Bessa Jaqueline Amaral , Mugnol Tatiana , Wolf Jonas , Boeira Thais da Rocha , Lunge Vagner Ricardo , Coser Janaina
Published: August 2023

Abstract Objective To investigate the presence of cervical infection by human papillomavirus (HPV) and associated factors in older women Method A cross-sectional, retrospective descriptive study with a quantitative approach was conducted. The sample comprised 106 women aged 60 years or over, seen at public health services of a city in southern Brazil, who underwent cervical cell collection for cytological analysis and molecular detection of HPV DNA. Clinical and sociodemographic data were collected using a standardized questionnaire and from Pap test result Results Patient age was 60-82 years, with a mean of 64.9 ± 5.1 years. HPV was detected in 14 (13.2%) of the study participants and 8 viral types were identified, the majority (n=7; 87.5%) of high oncogenic risk. Chi-square analysis revealed that positive HPV cases were associated with a higher number of sexual partners (p= 0.018). On cytology, most of the women (n=102; 96.2%) had a negative result for intraepithelial lesion or malignancy, and two (1.8%) had abnormal cytology, but neither were positive for HPV infection on molecular testing. Of the 10 women evaluated at two visits, seven (70%) tested negative for HPV infection on both evaluations, two (20%) eliminated the HPV infection, and one (10%) showed conversion to positive infection status. None of the cases had persistent infection. Conclusion Older women are susceptible to HPV infection and to the lesions caused by the virus. This group should therefore continue regular cytological screening.