bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of Softwer Applications in Water Quality Assesment
Authors: Skenderović Isat , Adrović Avdul , Bajrić Alen , Skenderović Ibro
Published: October 2024

Nowadays, we have many specific programs (software packages) which are used for statistic analysis of water quality in aquatic ecosystems. Selected parameters used in this paper are physicochemical and biological, and are valorized on the example of the river Spreča analysis. Researches have show that there is a correlation between the physicochemical value and biological indicators related to the assessment of the water quality of river Spreča. The composition of the zoobenthos community of river Spreča shows β-mesosaprobic character in the upper course of the river, while, according to the researches, the lower part of the watercourse shows polysaproby character. Similarity of ichthyopopulation on localities of research is tested by the Bray – Curtis similarity cluster analyses, which have shown that the greatest degree of similarity is visible in localities 1. and 3. In a special group are separated samples from the site 4. and 5. with a degree of similarity of 93,86%. Shanon- Waever's diversity index was calculated for all 6 sites researches.
Resource Description Language for Distributed RESTful Service Permission Management
Authors: Beshiri Arbër
Published: October 2024

In this paper is defined a description language for REST services in order to enable finegrained permission declaration for authorization purposes. These services are managed by a specific service in the distributed environment. Through a specific service provides permission and workflow management that are distributed in many REST services. The description enables data filtering of services based in parameters. The service permissions are based on HTTP operations and they are identified by unique URLs. The service is implemented separately, while the permission management is delegated in the central service which coordinates all other interacting services.
Model of Well Interference During Waterflooding of a Layered Heterogeneous Oil Reservoir within the Framework of the CRM Modeling Concept
Authors: Glushakov A. A. , Arhipov A. I. , Aafanaskin I. V.
Published: October 2024

The main types of CRM models (Capacitance Resistive Model) are considered. The advantage of CRM models over other types of models is the exclusion from consideration of reservoir pressure, information about which is usually unsystematic, scattered, and often unreliable. Particular attention in the work is paid to ML-CRM models that describe flow in layered formations. According to the literature, three models are described that are closest to the proposed one in this paper.The author’s model of interaction between wells during waterflooding of an oil reservoir with double permeability (layered heterogeneous reservoir) is proposed within the framework of the CRM modeling concept. Differences of the proposed model from models of other authors: 1) the model takes into account possible flows between layers due to vertical filtration across the bedding; 2) the model takes into account the two-phase nature of filtration during waterflooding, thanks to the use of a differential equation for the conservation of water volume in reservoir conditions, this approach is the most accurate and physically justified; 3) differential equations of the model are solved using numerical methods; 4) a system consisting of two layers with different filtration and capacitance properties is considered.The proposed model was tested on model and actual data. In the model example, when comparing various development indicators calculated using the CRM model and using a hydrodynamic simulator, the coefficient of determination is at least 0.9. This is a good result and indicates a high level of coincidence of the curves. In the actual example, when comparing those calculated using the CRM model and actual development indicators, the coefficient of determination is at least 0.7. This is also a good result for the actual data and indicates a high level of agreement between the calculated and actual curves.
Structure and evolution of metapolycentromeres
Authors: Grishko E. O. , Borodin P. M.
Published: October 2024

Metapolycentromeres consist of multiple sequential domains of centromeric chromatin associated with a centromere-specific variant of histone H3 (CENP-A), functioning collectively as a single centromere. To date, they have been revealed in nine flowering plant, five insect and six vertebrate species. In this paper, we focus on their structure and possible mechanisms of emergence and evolution. The metapolycentromeres may vary in the number of centromeric domains and in their genetic content and epigenetic modifications. However, these variations do not seem to affect their function. The emergence of metapolycentromeres has been attributed to multiple Robertsonian translocations and segmental duplications. Conditions of genomic instability, such as interspecific hybridization and malignant neoplasms, are suggested as triggers for the de novo emergence of metapolycentromeres. Addressing the “centromere paradox” – the rapid evolution of centromeric DNA and proteins despite their conserved cellular function – we explore the centromere drive hypothesis as a plausible explanation for the dynamic evolution of centromeres in general, and in particular the emergence of metapolycentromeres and holocentromeres. Apparently, metapolycentromeres are more common across different species than it was believed until recently. Indeed, a systematic review of the available cytogenetic publications allowed us to identify 27 candidate species with metapolycentromeres. Тhe list of the already established and newly revealed candidate species thus spans 27 species of flowering plants and eight species of gymnosperm plants, five species of insects, and seven species of vertebrates. This indicates an erratic phylogenetic distribution of the species with metapolycentromeres and may suggest an independent emergence of the metapolycentromeres in the course of evolution. However, the current catalog of species with identified and likely metapolycentromeres remains too short to draw reliable conclusions about their evolution, particularly in the absence of knowledge about related species without metapolycentromeres for comparative analysis. More studies are necessary to shed light on the mechanisms of metapolycentromere formation and evolution.
A new leaf pubescence gene, Hl1th, introgressed into bread wheat from Thinopyrum ponticum and its phenotypic manifestation under homoeologous chromosomal substitutions
Authors: Simonov A. V. , Gordeeva E. I. , Genaev M. A. , Li W. , Bulatov I. O. , Pshenichnikova T. A.
Published: October 2024

Blue-grain lines were created on the basis of the spring bread wheat variety Saratovskaya 29 (S29) with chromosome 4B or 4D replaced with chromosome 4Th from Thinopyrum ponticum. The leaf pubescence of the two lines differs from S29 and from each other. In this work, we studied the effect of these substitutions on the manifestation of this trait. To quantify pubescence, the LHDetect2 program was used to determine trichome length and number on the leaf fold microphotographs. The key gene Hl1 on chromosome 4B and another unidentified gene with a weak effect determine the leaf pubescence of the recipient S29. Their interaction leads to the formation of trichomes of up to 300 microns in length. Replacement of both copies of chromosome 4B with two copies of wheatgrass chromosome 4Th modifies leaf pubescence in line S29_4Th(4B) so that the leaf pubescence characteristic of S29 becomes more sparse, and trichomes of up to 600–700  µm in length are formed. Additionally, we described modification of pubescence in the substitution line S29_4Th(4D) where chromosome 4D that does not carry any pubescence gene was replaced. Under this substitution, trichomes of up to 400 µm in length were formed and the average length of trichomes on the underside of the leaf was reduced. The replacement of the Hl1 gene in the lines was also confirmed by the allelic state of the linked microsatellite marker Xgwm538. Thus, as a result of the studies, a new leaf pubescence gene introgressed from Th. ponticum into bread wheat was identified. We designated it as Hl1th. For the purpose of selection, we propose to use the unlicensed informative microsatellite markers Xgwm538 and Xgwm165, allowing chromosomes 4A, 4B, 4D and 4Th to be distinguished.
The effect of T. aestivum chromosomes 1A and 1D on fertility of alloplasmic recombinant (H. vulgare)-T. aestivum lines depending on cytonuclear compatibility
Authors: Pershina L. A. , Trubacheeva N. V. , Shumny V. K.
Published: October 2024

The effect of T. aestivum L. chromosomes 1A and 1D on fertility of recombinant bread wheat allolines of the same origin carrying the cytoplasm of barley H. vulgare L. and different levels of cytonuclear compatibility was studied. Alloline L-56 included mainly fully sterile (FS) and partially sterile (PS) plants, alloline L-57 included partially fertile (PF) plants and line L-58 included fertile (F) ones. Analysis of morphobiological traits and pollen painting indicated complete or partial male sterility in plants of allolines L-56 and L-57. To differentiate genotypes with cytonuclear coadaptation and genotypes with cytonuclear incompatibility, PCR analysis of the 18S/5S mitochondrial (mt) repeat was performed. Heteroplasmy (simultaneous presence of barley and wheat mtDNA copies) was found in FS, PS, PF and some F plants, which was associated with a violation of cytonuclear compatibility. Wheattype homoplasmy (hm) was detected in the majority of the fertile plants, which was associated with cytonuclear coadaptation. The allolines used as maternal genotypes were crossed with wheat-rye substitution lines 1R(1A) and 1R(1D). In F1, all plants of PF×1R(1A) and PF×1R(1D) combinations were fertile, and in F2, a segregation close to 3 (fertile) : 1 (sterile) was observed. These results showed for the first time that chromosomes 1A and 1D carry one dominant Rf gene, which controls the restoration of male fertility of bread wheat carrying the cytoplasm of H. vulgare. All plants of F1 combinations FS×1R(1A), FS×1R(1D), PS×1R(1A), PS×1R(1D) were sterile, which indicates that a single dose of genes localized on wheat chromosomes 1A or 1D is not enough to restore male fertility in FS and PS plants. All plants of hybrid combinations F(hm)×1R(1A) and F(hm)×1R(1D) in both F1 and F2 were fertile, that is, fertility of allolines with cytonuclear coadaptation does not depend on wheat chromosomes 1A and 1D.
Genotype imputation in human genomic studies
Authors: Berdnikova A. A. , Zorkoltseva I. V. , Tsepilov Y. A. , Elgaeva E. E.
Published: October 2024

Imputation is a method that supplies missing information about genetic variants that could not be directly genotyped with DNA microarrays or low-coverage sequencing. Imputation plays a critical role in genome-wide association studies (GWAS). It leads to a significant increase in the number of studied variants, which improves the resolution of the method and enhances the comparability of data obtained in different cohorts and/or by using different technologies, which is important for conducting meta-analyses. When performing imputation, genotype information from the study sample, in which only part of the genetic variants are known, is complemented using the standard (reference) sample, which has more complete genotype data (most often the results of whole-genome sequencing). Imputation has become an integral part of human genomic research due to the benefits it provides and the increasing availability of imputation tools and reference sample data. This review focuses on imputation in human genomic research. The first section of the review provides a description of technologies for obtaining information about human genotypes and characteristics of these types of data. The second section describes the imputation methodology, lists the stages of its implementation and the corresponding programs, provides a description of the most popular reference panels and methods for assessing the quality of imputation. The review concludes with examples of the use of imputation in genomic studies of samples from Russia. This review shows the importance of imputation, provides information on how to carry it out, and systematizes the results of its application using Russian samples.
Search for signals of positive selection of circadian rhythm genes PER1, PER2, PER3 in different human populations
Authors: Mishina A. I. , Bakoev S. Y. , Oorzhak A. Y. , Keskinov A. A. , Kabieva Sh. Sh. , Korobeinikova A. V. , Yudin V. S. , Bobrova M. M. , Shestakov D. A. , Makarov V. V. , Getmantseva L. V.
Published: October 2024

The diversity of geographically distributed human populations shows considerable variation in external and internal traits of individuals. Such differences are largely attributed to genetic adaptation to various environmental influences, which include changes in climatic conditions, variations in sleep and wakefulness, dietary variations, and others. Whole-genome data from individuals of different populations make it possible to determine the specific genetic sites responsible for adaptations and to further understand the genetic structure underlying human adaptive characteristics. In this article, we searched for signals of single nucleotide polymorphisms (SNPs) under selection pressure in people of different populations. To identify selection signals in different population groups, the PER1, PER2 and PER3 genes that are involved in the coordination of thermogenic functions and regulation of circadian rhythms, which is directly reflected in the adaptive abilities of the organism, were investigated. Data were analyzed using publicly available data from the 1000 Genomes Project for 23 populations. The Extended Haplotype Homozygosity Score statistical method was chosen to search for traces of selection. The comparative analysis performed identified points subject to selection pressure. The SNPs were annotated through the GWAS catalog and manually by analyzing Internet resources. This study suggests that living conditions, climate, and other external factors directly influence the genetic structure of populations and vary across races and geographic locations. In addition, many of the selection variants in the PER1, PER2, PER3 genes appear to regulate biological processes that are associated with major modern diseases, including obesity, cancer, metabolic syndrome, bipolar personality disorder, depression, rheumatoid arthritis, diabetes mellitus, lupus erythematosus, stroke and Alzheimer’s disease, making them extremely interesting targets for further research aimed at identifying the genetic causes of human disease.
Genetic aspects of lactase deficiency in indigenous populations of Siberia
Authors: Malyarchuk B. A.
Published: October 2024

The ability to metabolize lactose in adulthood is associated with the persistence of lactase enzyme activity. In European populations, lactase persistence is determined mainly by the presence of the rs4988235-T variant in the MCM6 gene, which increases the expression of the LCT gene, encoding lactase. The highest rates of lactase persistence are characteristic of Europeans, and the lowest rates are found in East Asian populations. Analysis of published data on the distribution of the hypolactasia-associated variant rs4988235-C in the populations of Central Asia and Siberia showed that the frequency of this variant increases in the northeastern direction. The frequency of this allele is 87 % in Central Asia, 90.6 % in Southern Siberia, and 92.9 % in Northeastern Siberia. Consequently, the ability of the population to metabolize lactose decreases in the same geographical direction. The analysis of paleogenomic data has shown that the higher frequency of the rs4988235-T allele in populations of Central Asia and Southern Siberia is associated with the eastward spread of ancient populations of the Eastern European steppes, starting from the Bronze Age. The results of polymorphism analysis of exons and adjacent introns of the MCM6 and LCT genes in indigenous populations of Siberia indicate the possibility that polymorphic variants may potentially be related to lactose metabolism exist in East Asian populations. In East Asian populations, including Siberian ethnic groups, a ~26.5 thousand nucleotide pairs long region of the MCM6 gene, including a combination of the rs4988285-A, rs2070069-G, rs3087353-T, and rs2070068-A alleles, was found. The rs4988285 and rs2070069 loci are located in the enhancer region that regulates the activity of the LCT gene. Analysis of paleogenomic sequences showed that the genomes of Denisovans and Neanderthals are characterized by the above combination of alleles of the MCM6 gene. Thus, the haplotype discovered appears to be archaic. It could have been inherited from a common ancestor of modern humans, Neanderthals, and Denisovans, or it could have been acquired by hybridization with Denisovans or Neanderthals. The data obtained indicate a possible functional significance of archaic variants of the MCM6 gene.
The potential for improving the efficacy of treatment for irritable bowel syndrome with a multi-target drug alverine citrate plus simethicone: The Expert Panel Statement
Authors: Minushkin Oleg N. , Khlynova Olga V. , Sitkin Stanislav I. , Yakovenko Emilia P. , Kravchuk Yuri A. , Seliverstov Pavel V. , Belousova Elena A.
Published: October 2024

The irritable bowel syndrome (IBS) is one of the most prevalent functional gastrointestinal disorders. However, at most, one-third of IBS patients are satisfied with the results of their treatment. A combination of pharmaceuticals or multi-target drugs should be used for the treatment to be effective due to the complexity of IBS pathophysiology. The Russian Expert Panel in gastroenterology, including functional gastrointestinal disorders, currently considered to be disorders of gut-brain interaction, at its open session has discussed the possibilities to increase the efficacy of treatment of patients with IBS with a multitargeted agent alverine citrate combined with simethicone registered under the trade name of Meteospasmyl® (Mayoly Pharma, France) and adopted the respective resolution. Based on the results of multiple experimental and clinical studies, the experts declared that the combination of alverine citrate with simethicone relieves pain through the alleviation of its main mechanisms (spasms, flatulence, visceral hypersensitivity, and inflammation), and normalizes bowel movements demonstrating the normokinetic (eukinetic) properties. All clinical effects of the combination of alverine citrate and simethicone are prolonged. Alverine citrate combined with simethicone improves patients’ quality of life, including their psychological well-being. Due to the efficacy and good safety profile, it is possible to use the combination of alverine citrate and simethicone as on-demand and ex juvantibus treatment. The combination of alverine citrate and simethicone is a single selective antispasmodic that allows for a simultaneous solution of two clinical challenges: to rid the patient of abdominal pains and to properly prepare the patient for instrumental examinations (colonoscopy, abdominal ultrasound, and radiological examination), due to a high simethicone dose and spasmolytic properties of alverine citrate. In addition, Meteospasmyl® is a single antispasmodic, which has demonstrated high efficacy and safety in a clinical study of its combination with a probiotic (Probiolog® IBS), containing the strains (Lactobacillus plantarum CECT 7484, Lactobacillus plantarum CECT 7485, and Pediococcus acidilactici CECT 7483) acting on all IBS pathogenesis steps. This is extremely important, considering the proven role of gut dysbiosis in IBS pathophysiology.
Modeling of the heat transfer process during thermite welding of railway rails
Authors: Galay Marina S. , Sidorov Eduard S.
Published: October 2024

Subject of research: study of heat distribution process during thermite welding of railway rails
The purpose of the study: to study the heat exchange process of the “mold – weld – rail” system by modeling in a special program for casting processes LVMFlow product.
Methods and objects of research: the object of research is rails welded joints. The research method is modeling the thermite welding process of rails in the LVMFlow software product.
The main results of the study: 3D models of heat transfer of the casting “mold – weld – rail” system have been developed taking into account phase transitions. Based on the proposed models distribution temperature thermograms fields are presented along section of welded joint and along length of the welded joint. The simulation results are confirmed by results of experiments.
Les Eucalyptus des Iles de la Sonde. 4e partie
Authors: Martin B. , Cossalter Christian
Published: October 2024

Après avoir décrit les peuplements naturels d'Eucalyptus urophylla dans l'ancienne partie portugaise du Timor, les auteurs poursuivent cette description dans la partie indonésienne de l'île et dans les petites îles de Flores, Adonara, Lomblen et Wetar.Les peuplements naturels d'Eucalyptus alba dans l'ancienne partie portugaise du Timor sont également décrits.Cette partie se termine par un examen de la récolte de graines par le C.T.F.T. dans ces peuplements naturels.
Activités alimentaires journalières de la chamelle gestante dans son milieu naturel
Authors: Mallem Khalid , Chehma Abdelmadjid , Huguenin Johann
Published: October 2024

Contexte : Les ressources fourragères limitées dans le Sahara contraignent le dromadaire à exploiter les vastes déserts à son avantage. Il est intéressant de surveiller les habitudes alimentaires quotidiennes du dromadaire afin de saisir comment il parvient à exploiter ses ressources limitées de manière durable pour satisfaire ses besoins. Objectifs : Cette étude visait à déterminer les activités quotidiennes des chamelles gestantes dans leur milieu naturel. Méthodes : Ce travail a été mené dans les parcours sahariens de la région d’El Oued (sud-Est de l’Algérie) où trois chamelles gestantes ont été suivies pendant l’hiver dans un parcours de type erg. Les données ont été recueillies entre le moment de sortir pour le broutage et le retour aux campements, pour une durée de 45 minutes à une heure pour chaque chamelle. Résultats : Le terrain montre que le broutage était l’activité diurne dominante, occupant 57 % du temps, suivi du déplacement, puis les autres activités comme la rumination et l’abreuvement. De plus, la flore disponible était presque entièrement composée de vivaces. Les espèces les plus appétées ne sont pas obligatoirement les plus abondantes. De plus, les chamelles gestantes ont sélectionné un total de 6 espèces de plantes vivaces sur les 9 plantes disponibles, les espèces fourragères les plus broutées sont Anabasis articulata et Cornulaca monacantha représentant respectivement 47,8 % et 33,9 %. Du fait de son activité alimentaire ambulante, la chamelle gestante a parcouru 15,4 à 20,5 km par jour, ce qui est inférieur aux distances parcourues par les chamelles vides. En revanche, elles étaient plus sélectives. La quantité de matière sèche ingérée a été estimée à 9,6 kg MS/jour, soit de 2,4 kg MS/100 kg de PV/jour. Conclusion : Les chamelles gestantes par rapport aux chamelles vides se nourrissent davantage en parcourant des distances moindres.
BLEU BLANC VERT : L’ALGERIE AU CARREFOUR D’UNE TRANSFORMATION SOCIALE A TRAVERS LA CULTURE
Authors: Civelekoğlu Tara
Published: October 2024

Bleu Blanc Vert est un roman de Maïssa Bey, paru en 2006, qui relate l’histoire algérienne, les événements sociaux, politiques et économiques qui se déroulent entre 1962-1992 dans 3 périodes de 10 ans, à travers un texte fictif. Les personnages du roman, Lilas et Ali sont deux algériens vivant dans le même immeuble dans la capitale, Alger et qui par la suite, tombent amoureux l’un de l’autre et se marient. Etant deux petits enfants en 1962, l’année où l’Algérie a acquis son indépendance et où les Français sont partis, Lilas et Ali s’expriment à la première personne du singulier dans les chapitres –qui leur sont consacrés- intitulés Lui/Elle pour transmettre leurs observations, leurs sentiments et leurs opinions. Ces observations sont très précieuses étant donné qu’elles permettent de comprendre la société algérienne de pré et de post indépendance, surtout l’ambiance multiculturelle partagée par les Français et les Algériens dans le cadre de la problématique identitaire. Dans ce travail réalisé, le but est d’essayer de comprendre, à travers une œuvre fictive, les transformations vécues par la société algérienne pendant 30 ans, autour des notions comme l’assimilation, l’altérité, l’interculturalité et l’acculturation et de réfléchir sur le rôle de ces éléments dans la formation de l’identité ethnique et nationale, dans la relation entre l’espace et l’identité et enfin dans la construction de l’identité féminine.
ORTAÖĞRETİM FRANSIZCA DERSİ ÖĞRETİM PROGRAMLARININ DEĞERLENDİRİLMESİ (1993–2017)
Authors: Kirazlı Gülden , Saraç Füsun
Published: October 2024

Tüm dünyada olduğu gibi ülkemizde de, uzun yıllardır bilim, teknoloji, ulaşım ve iletişim araçlarının gelişimi ve ilerleyişi, yabancı dile olan ihtiyacı arttırmıştır. Artan bu ihtiyaç ve iletişim sorunları, yabancı dil öğrenimi ve öğretimi konusunu sıklıkla gündeme taşımaktadır. Yabancı dil öğretimi; öğretmen, öğrenci, kurum, yöntem, ders araç gereçleri ve eğitim-öğretim programından oluşan çok boyutlu bir süreçtir. Bu araştırmada, Cumhuriyet döneminde, ortaöğretim Fransızca dersi için Milli Eğitim Bakanlığı tarafından hazırlanıp uygulanan 1993, 2006, 2011 ve 2017 öğretim programlarının biçimsel yapıları, vizyonu, genel amaç ve hedefleri, içerikleri, öğrenme alanları, öğrenme-öğretme süreçleri ve ölçme değerlendirme öğeleri esas alınarak, programların karşılaştırmalı olarak incelenmesi hedeflenmiştir. Araştırma, nitel araştırma deseni benimsenerek gerçekleştirilmiştir. Nitel araştırma yöntemlerinden doküman incelemesi yönteminin kullanıldığı bu çalışmada, temel olarak Milli Eğitim Bakanlığı tarafından yayımlanan ortaöğretim programları ve “Tebliğler Dergisi” incelenmiş, ilgili kaynaklar taranmış ve Fransızca dersi öğretim programlarının, tarihsel süreçteki durumunun ortaya konmasına yönelik veriler toplanmıştır. Yapılan çalışmanın sonuçlarına göre, 1993 programının diğer programlara göre eksiklerinin olduğu ve sözü edilen eksikliklerin 2017 programına kadar, tamamlanmaya çalışıldığı anlaşılmıştır. Programların tümünde, öğrenci merkezli bir dil öğretimi bakış açısının olduğu belirlenmiştir. Öğrenci merkezli bakış açısı, son programa gelindiğinde, öğrencinin bir yandan dil öğrenirken bir yandan da, daha dışa dönük, sosyal ve kültürel olarak kendini geliştirebilen bir birey haline gelmesi gerektiğini vurgulayan bir bakış açısına dönüşmüştür. 2017 programında, öğrencinin, sorumluluk bilinci kazanmış, bilişsel ve psiko-sosyal becerilerini, problem çözme ve kendi kararlarını verebilme yönünde kullanabilen bir birey olarak değerlendirilmesi gerektiği tespit edilmiştir.
SAVAŞ DÖNEMİNDE KÜLTÜRE SIĞINMAK: TONNERU NO MORI 1945’TE JAPON KIRSALININ KÜLTÜREL MOTİFLERİ
Authors: Salğar Habibe
Published: October 2024

Japonya'da savaş zamanına ilişkin anlatılar çeşitlilik göstermektedir ve bunun en önemli nedeninin kişiden kişiye farklılık gösteren kolektif bir travma olduğu söylenebilir. Japon çocuk edebiyatında da savaş temasının olduğu bazı çocuk romanlarında kırsal kültürel yapıya dikkat çekildiği gözlemlenebilir. Savaş döneminde kırsal alanların, kültürel dokunun, geleneksel yapının önemini anlatan örnekleri Japon çocuk edebiyatında görmek mümkündür. Bu çalışmada, Eiko Kadono'nun Tonneru no Mori 1945 (2015) adlı romanındaki başkahramanın farklı bir sosyal çevreye uyum sağlama süreci Vygotsky'nin sosyokültürel teorisi bağlamında incelenmiştir. Tokyo'dan tahliye hikayesinin edebi bir uyarlaması olan romanda savaş koşulları ve savaştan kaçmak için sığındıkları kırsal kesimdeki Japon kültürel motifler açıkça görülebilmektedir. Kırsal alan, kent hayatından farklı olarak doğayla iç içe bir yaşam sunar ve bu yaşam başkahramanın biyofobik duygulara kapılmasına yol açar. Başkahraman İko'nun bu biyofobik duyguları, Tokyo'dan sonra yaşadığı kırsal bölgede okul ile ev arasındaki güzergâh üzerindeki ‘orman tüneli’ (tonneru no mori) adı verilen bir yol nedeniyle ortaya çıkar. Başkahramanın babası Seizō’nun Japon kültüründe doğa inancına içkin değerleri öğreterek bu duyguyu yenebilmesi için çocuğunun psikososyal gelişimine destek olduğu görülmektedir. Bu araştırma, Japonların kültürel yapıyı çocuklara öğretme biçimine bir örnek olarak edebiyatın işlevselliğine yer verirken, çocuklarda edebi metinler aracılığıyla kültür öğrenimine model oluşturulabileceğine işaret etmektedir.
Um programa piloto de capacitação específico é capaz de aumentar a sistematização da abordagem do conteúdo lutas em aulas de educação física curricular?
Authors: Andreato Leonardo Vidal , Tavares Ana Flávia dos Reis , Gondim Denis Foster , Kohl Henrique Gerson , Jurema Jefferson , Paiva Leandro
Published: October 2024

Objetivo: Avaliar a efetividade de um programa de capacitação para aumentar a sistematização da abordagem do conteúdo lutas nas aulas de Educação Física em Barcelos-AM. Metodologia: Dez docentes do Ensino Fundamental foram divididos em: 1) grupo intervenção, que participou de uma capacitação de curta duração voltada ao ensino das lutas na escola; e 2) grupo controle, que não recebeu nenhuma orientação durante a pesquisa. No início e no fim do ano letivo, os docentes e 30 discentes responderam a um questionário semiestruturado relacionado às lutas na Educação Física escolar. Resultados: O curso de capacitação exerceu pouca influência sobre o entendimento do corpo docente acerca da adequação do conteúdo lutas no currículo escolar e sobre o engajamento para uma efetiva sistematização da abordagem das lutas nas intervenções docentes (apesar de 60% terem relatado o alto impacto do curso). Contudo, entre os alunos, a capacitação parece ter influenciado positivamente para que as aulas envolvendo as lutas fossem experienciadas com um percentual significativo de satisfação (66,7% gostaram), além de despertar interesse para novas experiências envolvendo lutas (100% gostariam de ter outras aulas). Conclusão: O modelo proposto propiciou importantes reflexões didático-pedagógicas; porém, apresentou limitações que precisam ser repensadas para obtenção de impactos significativos.
A feminist lens on gender equality in high-rank research positions at the National Autonomous University of Mexico
Authors: Cortina Regina , Quezada Romina
Published: October 2024

This case study of the National Autonomous University of Mexico (UNAM), Mexico´s oldest and largest university, examines the persistence of gender hierarchies in Mexican higher education. The chapter explores ways to address such hierarchies and contribute to women’s emancipation from a human rights perspective. The analysis delves into the presence and influence of women academics across career levels, fields of study, and access to higher wages in the University. It shows that, overall, the creation of universal laws that support gender equality has led to advances in parity among men and women academics. However, it also reveals that women still struggle to achieve high-rank research positions because persistent hierarchies and the glass ceiling impede women´s achievements more often than those of their male colleagues. The first part of the chapter explains the positive changes towards gender equality in international law documents, which in turn influenced Mexican laws. It then builds on Nathalie Heinich’s theory on the visibility of women in academia to explain why women face a glass ceiling barrier in the higher echelons of research, knowledge production and leadershippositions. 1 The case study of UNAM’s women academics follows the theoretical discussion andthe contributions of feminist theory to the current human rights framework for gender equality. Finally, we offer recommendations on how institutions of higher education can better support the advancement of women in academic life.
A educação comparada e a insustentável leveza do ser
Authors: Gomes Candido Alberto
Published: October 2024

Um balanço da Sociedade Brasileira de Educação Comparada, aos 40 anos, evoca a insustentável leveza do ser, conjugando a leveza da busca da liberdade e o peso concreto dos fatos. Esboçando esta contínua tensão, destacamos o objetivo inicial de abrir janelas e portas ao mundo, de modo a superar tanto uma educação introjetada como um cosmopolitismo neocolonial. Assim, buscava-se debater uma perspectiva para as ciências da educação. Levantamento em 2013 arrolou 97 artigos publicados em 1999-2014. Nesta tentativa, nos deparamos com a estimativa preliminar de cerca de 840 trabalhos publicados digitalmente de 2019 a junho de 2023. Esta explosão reflete o contexto da globalização, das avaliações comparativas e dos estímulos à competição pela eficiência, não necessariamente pela igualdade. Este trabalho conclui com indagações sobre as teias quantitativas, as linhas de montagem em que nos enredamos, em vez de ter a calma para refletir profundamente sobre os seus significados e implicações. Seríamos marionetes de um gigantesco espetáculo, de simulacro e simulação da leveza e da solidez?
Como aprender perguntando a partir de uma unidade de aprendizagem
Authors: Galle Lorita Aparecida Veloso , Lima Valderez Marina do Rosário
Published: October 2024

Este estudo foi realizado no contexto de uma Unidade de Aprendizagem (UA) sobre alimentos, em uma turma de 20 estudantes de nono ano do Ensino Fundamental de uma escola pública estadual do interior do Rio Grande do Sul, Brasil, no componente curricular de Ciências. O objetivo geral da investigação foi compreender as características das perguntas propostas pelos estudantes no decorrer da UA. Para tanto, pretendeu-se dar resposta para a pergunta: como se caracterizam as perguntas formuladas pelos estudantes no desenvolvimento de uma UA sobre alimentos? As informações analisadas foram perguntas propostas pelos estudantes relativas à temática “alimentos”, realizadas durante o desenvolvimento da UA. Os resultados fornecem indicativos de que, ao longo das atividades, o percentual de perguntas de caráter investigativo avançou consideravelmente. Como conclusão, afirma-se que isso pode estar associado aos pressupostos do modo de organização dos conhecimentos escolares que tem como princípio a pesquisa, sendo esta capaz de mobilizar a curiosidade epistêmica, o que pode favorecer a emergência de um número significativo de perguntas investigativas. Defende-se, portanto, a relevância de desenvolver ações educativas que instiguem ao questionamento, superando a mera busca por informações ou explicações.
TAQNIN FIKIH : Transformation of Marriage Law in Indonesia
Authors: Fernanda Ahmad , Salma Salma , Hidayat Rahmat
Published: October 2024

Indonesia has a pluralist background, so realizing one rule accommodating all interests is a challenge. Among them is the unification of the rules on marriage. The purpose of this study is to explore historically the growth and development of taqnin from time to time, taqnin of marriage law in Indonesia, the legality of post-taqnin marriage law, challenges and opportunities, and challenges of taqnin. This literature research method uses quantitative with an exploratory analysis approach, namely analyzing fikih munakahat products transformed into positive law. Data processing by managing library materials (library research). Secondary data sources are Law Number 1 of 1974 concerning Marriage and the Compilation of Islamic Law (KHI) and books and articles based on OJS (Open Journal System). Techniques for analyzing the data obtained were exploratory and descriptive analysis using the techniques of reduction, display, and verification. The results showed that, based on historical aspects, taqnin had been pursued since the abasiyah daulah but has experienced ups and downs in its implementation. Second, The transformed legal product is dynamic. Third: Munakahat jurisprudence has gone through the process of taqnin to have the legality of state law, so it becomes the primary source in marriage issues. Fourth: The opportunities and challenges faced are internal and external.
The Determinants Factors of Personal Mastery Among Clinical Nurse Practitioners in Indonesia
Authors: Beni Kornelis Nama , Nursalam Nursalam , Hasinuddin M , Priyantini Diah , Ayatulloh Daviq
Published: October 2024

Introduction: Human resources of nursing who have low personal mastery have an impact on the quality and productivity of nursing services. Several factors have been studied to be associated with the low personal mastery of nurses. The purpose of this study was to analyze the factors that’s influencing personal mastery improvement of clinical nurse practitioners in a hospital.
Methods: This study applied cross sectional design with 120 respondents through cluster sampling technique in one of Surabaya Hospital. Data were collected using the personal mastery factors questionnaire that has been tested for validity and reliability. The variable included training and development, leadership, attitudes, competencies, motivation, personal values, job design and personal mastery of nurses. Data were analyzed using multiple linear regression.
Results: The result showed that competence, personal values and job design factors partially influenced the personal mastery (p = 0.006), (p = 0.001), (p = 0.005). Training and development, leadership, attitude and motivation have not influenced on personal mastery (p = 0.871), (p = 0.352), (p = 0.900), (p = 0.312). Simultaneously development and training, leadership, attitudes, competencies, motivation, personal values and job design factors was influenced the personal mastery of nurses' (p = 0.000). The influenced independent’s variable on personal mastery of clinical nurse practitioners is 58.1%.
Conclusions: Personal mastery of clinical nurse practitioners was increased by improving the competence, strengthening of the personal values and design a good job. Further studies are warrant to examine other factors that can improve nurses' personal mastery such as organizational culture, reward systems that affect the performance of clinical nurse practitioners.
Social Entrepreneurship and Water Disclosure: A Bibliometric Analysis
Authors: Santoso Arif , Sari Puji Novita , Rahayu Selvia , Lestari Sari , Srimaryani Srimaryani
Published: October 2024

In a world increasingly concerned with environmental sustainability and corporate responsibility, the relationshiop between water disclosure, social entrepreneursip, and the cultivation of the entrepreneurship ecosystem emerges as a critical nexus. Water is the essensial need for human life and business life. Entrepreneurial concern for these issues also influences access to financing and market. These problems have received much attention from researcher, but there has been no attempt to synthesize the results. This research aim to explores and synthesize the literature related water disclosure and social entrepreneurship in the entrepreurship ecosystem. The analysis was based on Scopus database in the last decade and PRISMA protocol and VOSViewer was used. This study performs co-occurrence and co-authorship analysis. Social entrepreneurship, sustainability, innovation, water disclosure, and strategy are some of the frequently emerging variables. The results of network analysis show that social entrepreneurship and water disclosure are linked by variable stakeholder, economic and social effect, and sustainable development. It highlights that water disclosure and social entrepreneurship is a mandate of the stakeholders and its implication is that the entrepreneurial ecosystem has moved towards sustainable development.
Complementing Mammography Screening with Automated 3D Ultrasound in Women with High-Density Breasts
Authors: Garanina А. E. , Kholin A. V.
Published: October 2024

Background. In early breast screening structure, an important factor is breast density. Women with types C and D breast density according to American College of Radiology (ACR) classification have 4–6-fold increased risk of cancer compared to women with type A breast density. With this type of density, the effectiveness of diagnostic mammography (MG) is significantly decreased. Today, automated breast 3D ultrasound can be considered as an additional screening method in women with breast structure types C and D according to ACR.Objective: to perform a comparative analysis of the diagnostic efficacy of 2D and 3D ultrasound in women aged 40 years and older with high breast tissue density.Material and methods. Retro-prospective, observational, single-center study was conducted. From February 2019 to May 2023, 1283 patients aged 40 years and older were examined. The patients were divided into two groups. In group A, women underwent 2D ultrasound and MG. In group B, additionally to these methods, 3D ultrasound was performed. In both groups, the results were evaluated according to Breast Imaging-Reporting and Data System (BI-RADS). Based on the obtained data, the following indicators were determined: positive (PPV) and negative (NPV) predictive values, sensitivity, specificity and accuracy of all methods. For 2D and 3D ultrasound, the predictive model areas under curve (AUC) of receiver operating characteristic (ROC) were calculated.Results. MG method showed PPV 0.89, NPV 0.93, sensitivity 0.53, specificity 0.99, and balanced accuracy 0.76. Indicators for 2D ultrasound demonstrated PPV 0.8, NPV 0.98, sensitivity 0.9, specificity 0.97, balanced accuracy 0.93, AUC ROC 0.968. The results for 3D ultrasound were as follows: PPV 0.97, NPV 0.97, sensitivity 0.9, specificity 0.99, balanced accuracy 0.94, AUC ROC 0.98.Conclusion. The diagnostic efficiency of breast automated 3D ultrasound in patients aged 40 years and older is comparable to 2D ultrasound in terms of sensitivity, and it’s better in terms of accuracy, specificity. The prognostic model of 3D ultrasound is also better compared to 2D ultrasound.
Evaluation of Accessory Infraorbital Foramen with Cone Beam Computed Tomography
Authors: Kabak S. L. , Melnichenko Yu. M. , Ioufereva M. P. , Pilchuk A. V.
Published: October 2024

Objective: to assess the incidence, number and position of accessory infraorbital foramina (AIOF) according to cone beam computed tomography (CBCT).Material and methods. CBCT data from 156 patients who received dental care at a private medical center in Minsk (The Republic of Belarus) in 2018–2023 were analyzed.Results. In 29 (18.6%) patients, 38 AIOF were found. Unilateral doubling of the infraorbital foramen was more common than bilateral (21 patients compared to 8). In 1 case, the presence of two AIOF simultaneously on one side was noted. They were located medial and superior relative to the main infraorbital foramen at a distance 3.73–14.5 mm from it. In 2 of 13 patients with simultaneously visualized upper and lower jaws, an accessory mental foramen was found on the AIOF side. AIOF were more often identified on the left side (p<0.05); no gender differences in their occurrence were detected.Conclusion. The obtained results demonstrate a high frequency of infraorbital foramen doubling. To increase the effectiveness of surgical manipulations in the middle third of the face and prevent iatrogenic neurological complications, it is recommended to conduct a preoperative CBCT to clarify the localization of the main and accessory infraorbital foramina.
Potential of Chest Radiography in Primary Diagnosis of Lung Cancer
Authors: Bereznikov A. V. , Shkitin S. O. , Tyurin I. E.
Published: October 2024

Objective: to evaluate the effectiveness of diagnostics for non-small cell lung cancer (LC) based on chest radiography/fluorography data for LC screening diagnostics during preventive medical examination and check-ups.Material and methods. The work was organized as a retrospective cohort study. The starting point of the study was chest radiography, the final point was the diagnosis of LC based on the results of low-dose computed tomography (LDCT) and tumor morphological examination. The patient sample was composed using inclusion and exclusion criteria and initially included 800 patients, then narrowed down to 788. Patients were divided into groups according to LC stage and depending on whether radiography during preventive measures made it possible to suspect LC verified within 3 months via LDCT for any reasons not related to the suspicion of a tumor process. The diagnostic coefficient and informative value of radiography were calculated for each stage of the established LC diagnosis.Results. The study showed that chest radiography does not allow establishing stage I LC diagnosis (J=0.00; p<0.05), it is low informative for stage II LC (J=0.25; p<0.05), and medium informative for stage III LC (J=0.80; p<0.05). Chest radiography does not reliably detect LC signs at early stages in 84.3% of cases.Conclusion. The obtained results indicate an insufficient sensitivity of radiography as a screening method, primarily for early LC diagnosis. The introduction of chest LDCT instead of radiography into the procedure for preventive medical examination and check-ups of the adult population approved by the Ministry of Health of the Russian Federation will increase LC detection at early stages by 5.37 times (95% confidence interval 3,77–7,64).
Contrast-Enhanced Mammography Accuracy in Assessing Preoperative Breast Tumor Size
Authors: Balbino M. , Ancona A. , Masino F. , Suriano S. , Cantore S. , Montatore M. , Guglielmi G.
Published: October 2024

Background. Breast cancer is a leading type of cancer in women. Imaging techniques (ultrasound, mammography, and magnetic resonance imaging (MRI)) play a crucial role in tumor detection and evaluation. The last emerging technique is contrast-enhanced mammography (CEM) which provides both morphological and functional information.Objective: to evaluate CEM accuracy in measuring breast tumor lesions. Material and methods. The study involved 69 patients followed by the Breast Unit from January 2018 to September 2023. Breast tumor dimensions measured in CEM in the pre-operative stage by three experienced radiologists were compared to the dimension obtained at the histological examination, the current gold standard in assessing tumor size. Results. We observed a slight overestimation by CEM compared to histology, with a difference between the two measurements not more than 10 mm. CEM underestimated the dimensions in 12 of 69 cases. Conclusion. The study demonstrated excellent CEM accuracy in preoperative assessment of breast tumors, consistent with previous findings in the literature. CEM could prove to be a valid and safer alternative to MRI in preoperative breast tumor measuring.