bluuebunny/crossref_metadata_2025 huggingface dataset:
Determinants of stunting among children aged 6 to 59 months in pastoral community, Afar region, North East Ethiopia: unmatched case control study
Authors: Kahssay Molla , Woldu Etsay , Gebre Abel , Reddy Surender
Published: February 2020

Background

Stunting is defined as a child with a height for-age Z-score less than minus two standard deviations. Globally, 162 million less than 5 years were stunted. In Ethiopia, Nationally the prevalence of stunting among under five children was 38.4% and in Afar it is above the national average (41.1%). This study was aimed to identify determinants of stunting among children aged 6 to 59 months in rural Dubti district, Afar region, North East Ethiopia, 2017.

Methods

Community based unmatched case-control study design was conducted among 322 (161 cases and 161 controls) children aged 6 to 59 months from March 2–30/ 2017. Simple random method was used to select 5 kebelles from 13 kebelles. Training was given for data collectors and supervisors. Data were entered to EPI data version 3.02 and exported to SPSS version 20 for analysis. Binary logistic regression analysis was used and variables with p-value < 0.25 on univariable binary logistic regression analysis were further analyzed on multivariable binary logistic regression analysis and statistical significance was declared at 95% CI.

Results

Being from a mother with no education (AOR = 4.92, 95%CI (1.94, 12.4), preceding birth interval less than 24 months (AOR = 4.94, 95% (2.17, 11.2), no ANC follow-up (AOR = 2.81, 95% (1.1.46, 5.38), no access to latrine (AOR =3.26, 95% CI (1.54–6.94), children born from short mother < 150 cm (AOR = 3.75, 95%CI (1.54, 9.18), not fed colostrum (AOR = 4.45, 95% CI (1.68, 11.8), breast fed for less than 24 months (AOR = 3.14, 95% CI (1.7, 5.79) and non-exclusive breast feeding (AOR = 6.68, 95% (3.1, 14.52) were determinants of stunting at 95% CI.

Conclusion

No maternal education, preceding birth interval less than 24 months, no ANC follow-up, no access to latrine, short maternal height, not feeding colostrum, duration of breast feed less than 24 months and non- exclusive breast feeding were determinants of stunting at 95% CI.
Correction to: Atypical hyperglycemia presentation suggests considering a diagnostic of other types of diabetes: first reported GCK-MODY in Perú
Authors: Lizarzaburu-Robles Juan Carlos , Gomez-de-la-Torre Juan Carlos , del Carmen Castro-Mujica María , Vento Flor , Villanes Sofia , Salsavilca Elizabeth , Guerin Chris
Published: February 2020

It was highlighted that the original article [1] contained an error regarding the nomenclature in the gene described.
Strategic intent of OBOR: enhancing energy supply resilience
Authors: Tang Loon Ching , Low Joyce M.W.
Published: February 2020

Since the launch of the One Belt, One Road (OBOR) initiative in 2015, China has announced its intention to invest in major infrastructure projects to promote trade and co-operation with its trading partners along OBOR. This paper examines the current level of trading and key projects underway along OBOR so as to provide insights to understand its strategic intent. In particular, a network model is constructed to analyze the impact to China current and future demand for energy under various conditions especially during prolonged periods of supply uncertainties. Since these key projects are closely connected to the current and proven oil and natural gas reserves locations, the findings propound the OBOR initiative is more than trade and a key motivation is to enhance China’s energy supply resilience amongst other imperatives.
Carbon dioxide angiography during peripheral angioplasty procedures significantly reduces the risk of contrast-induced nephropathy in patients with chronic kidney disease
Authors: Diamantopoulos Athanasios , Patrone Lorenzo , Santonocito Serafino , Theodoulou Iakovos , Ilyas Shazhad , Dourado Renato , Game David , Karunanithy Narayan , Patel Sanjay , Zayed Hany , Katsanos Konstantinos
Published: February 2020

Background

Iodinated contrast media are amongst the most frequently prescribed medications, however, their use is not without complications. With contrast-induced nephropathy constituting a major concern, alternative non-iodine based approaches have been explored such as carbon dioxide angiography. The purpose of this study is to report the incidence of contrast-induced nephropathy following carbon dioxide angiography in patients with impaired renal function that underwent peripheral angioplasty compared with a historical cohort of patients that underwent angioplasty with use of solely iodine contrast medium. The historical cohort of patients treated with iodinated contrast was used as control. Baseline demographics and renal function tests were recorded. Primary outcome was incidence of contrast-induced nephropathy within 48–72 h post intervention. Receiver-Operating-Characteristic curve analysis was used to correlate the volume of iodinated contrast with the risk of contrast-induced nephropathy.

Results

Carbon Dioxide was used as an alternative to iodinated contrast media in patients with impaired renal function (eGFR<60mls/min/1.73 m2) undergoing peripheral angioplasty procedures. Fifty, consecutive patients (baseline eGFR = 38.6 ± 13.2mls/min/1.73 m2) were included in a prospective clinical audit. These were matched (1:2) with a historical cohort of patients (baseline eGFR = 43.3 ± 12.2mls/min/1.73 m2) treated with Iodinated contrast media. The incidence of contrast-induced nephropathy was 14% (n = 7/50) in case of carbon dioxide vs. 29% (n = 29/100) in the matched cohort group (p = 0.045). Receiver-Operating-Characteristic analysis showed that use of >25mls of contrast was 94.4% (95% CI:81–99%) sensitive in predicting contrast-induced nephropathy.

Conclusion

Carbon dioxide imaging during peripheral angioplasty procedures protects against contrast-induced nephropathy. Use of >25mls of iodinated contrast media in high-risk patients is a predictor of contrast-induced nephropathy.
Extended stable factor method for the inverseQ-filter
Authors: Li Yong , Zhang Gulan , Duan Jing , He Chengjie , Du Hao , Luo Fan , Zhan Yizong , Wang Jia
Published: February 2020

The commonly used stable factor methods for the inverse [Formula: see text]-filter achieve good performance in seismic data processing; however, the constant gain-limit assumption in these methods is not associated with the effective frequency band of seismic data and cannot obtain desirable results with high resolution and high signal-to-noise ratio (S/N). Our extended stable factor method for the inverse [Formula: see text]-filter extends these methods by introducing two parameters and constant or self-adaptive gain limit to achieve the desirable high-resolution and high-S/N result. The extended stable factor method for the inverse [Formula: see text]-filter can be implemented in the frequency or time-frequency domain; the latter implementation achieves a higher S/N. Analysis of synthetic signals and field seismic data application illustrate that our method can produce a desirable high-resolution and high-S/N result.
Culture and PCR based detection of bacteria causing urinary tract infection in urine specimen
Authors: Pirkani Ghulam Sarwar , Awan Mohammad Arif , Abbas Ferhat , Din Mohammad
Published: February 2020

Objectives: Urinary tract infections are the second most common bacterial infections occurring at all ages and both sexes. The increasing rate of antibiotic resistance is a global concern. The use of routinely used antibiotics is resulting in treatment failure. The objective of this study was to diagnose the urinary tract infections by routine culture sensitivity test and by molecular methods.

Methods: This study was conducted in Microbiology laboratory, Bolan Medical Complex Hospital, Quetta, from July 1st to 31st March 2019. Isolates were identified biochemically by API20E & API20NE. Antibiogram was performed using disc diffusion Kirby Bauer technique. The 16S rDNA gene approach was used for molecular identification of bacterial isolates. The presence of the blaNDM-1 gene was identified by polymerase chain reaction (PCR).

Results: We isolated 146 bacterial isolates namely Escherichia coli (n=99) 67.80%, Klebsiella pneumoniae (n=33) 22.60%, Pseudomonas aeruginosa (n=11) 7.53% and Proteus mirabilis (n=3) 2.05% from 2032 urine samples. The resistance pattern was dominated by Multi Drug Resistance (MDR). Remarkably, four isolates of Escherichia coli (n=3) and Klebsiella pneumoniae (n=1) were displaying resistance against a range of antibiotics used in the study, including carbapenems but sensitive to tigecycline and polymyxins only, suggesting extensive drug resistance having blaNDM-1 gene.

Conclusion: This is the first report on direct molecular detection of bacterial pathogens from urinary tract infected patients in Balochistan. The presence of blaNDM-1 in different bacterial species and their extensive drug resistance pattern poses a significant clinical threat. Molecular detection of bacteria and resistant gene may reduce the diagnostic time of patients.

doi: https://doi.org/10.12669/pjms.36.3.1577

How to cite this:Pirkani GS, Awan MA, Abbas F, Din M. Culture and PCR based detection of bacteria causing urinary tract infection in urine specimen. Pak J Med Sci. 2020;36(3):391-395. doi: https://doi.org/10.12669/pjms.36.3.1577

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Diabetes Registry of Pakistan
Authors: Basit Abdul , Fawwad Asher , Baqa Kulsoom
Published: February 2020

Diabetes registries can be used to monitor the prevalence and incidence of diabetes. Diabetes registries are used in many countries for population management of diabetes, outcomes management, and development of Clinician finding Support Structure, for example, National Diabetes Registry (NDR) in Sweden and Singapore diabetes registry. According to 2nd National Diabetes Survey of Pakistan (NDSP) 2016-2017, overall 26.3% adult (≥20) suffer from diabetes (27.4 million people). Health Research Advisory Board (HRAB) of Pakistan has initiated the mission of developing disease registries countrywide. Diabetes Registry of Pakistan (DROP) under the supervision of Prof. Abdul Basit and Dr. Asher Fawwad to enumerate the degree of the national disease burden. For type 1 diabetes, Diabetes Registry of Pakistan for type 1 (DROP-1) has already started. DROP-1 can be a good pilot arm for developing the robust methodology for DROP. The upcoming and the ongoing research is periodically being linked with the registry to ensure its modernization. This registry is a useful tool for tracking the status of patient, in order to limit the burden of data collection. A web-based data entry system and automated random sampling has enabled useful data collection and tracking with relatively minimal effort.

doi: https://doi.org/10.12669/pjms.36.3.1877

How to cite this:Basit A, Fawwad A, Baqa K. Diabetes Registry of Pakistan. Pak J Med Sci. 2020;36(3):578-580. doi: https://doi.org/10.12669/pjms.36.3.1877

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The diversity of Anopheles blood feeding patterns suggests different malaria protection strategies in different localities
Authors: Chakim Irfanul , Pumpaibool Tepanata
Published: February 2020

Background: Malaria is a significant health burden for many countries worldwide. Insecticide-treated bed nets and mosquito repellent are considered effective methods for preventing Anopheles bites. However, changes in the biological properties of the vector have led to a reduction in their effectiveness. Most published studies have only investigated the human population factor, not the dynamics of vector behavior. Therefore, this study aims to investigate the importance of primary vector activity for selecting an appropriate malaria protection strategy.

Methods: Initially, active case detection (ACD) was carried out in western and eastern parts of Indonesia, Jambi and Sumba, to confirm their endemicity level. According to the 2016 national health report of Indonesia, Jambi has an annual parasite index (API) of 0.14 and Sumba has an API of 5.41.

A series of entomological observations were carried out to compare the biting activity of Anopheles vectors in two localities, with a total of 216 houses and 216 catchers (108 at each study site).

Results: The results indicated that endemicity at the sub-district level is higher than that at the provincial level. Only Anopheles balabacensi was found to be exophagic. Multiple comparisons found different biting times between the sites, suggesting that early evening (18.00-20.00) is most likely to be the time when mosquitoes transmit the Plasmodium parasite in Jambi, while during sleeping hours (21.00-01.00) is the peak biting time of Anopheles mosquitoes in Sumba.

Conclusions: The study demonstrates the importance of Anopheles species blood feeding patterns in selecting an appropriate malaria protection strategy.
Peptide arrays of three collections of human sera from patients infected with mosquito-borne viruses
Authors: Martinez Viedma Maria del Pilar , Kose Nurgun , Parham Leda , Balmaseda Angel , Kuan Guillermina , Lorenzana Ivette , Harris Eva , Crowe Jr. James E. , Pickett Brett E.
Published: February 2020

Background: Global outbreaks caused by emerging or re-emerging arthropod-borne viruses (arboviruses) are becoming increasingly more common. These pathogens include the mosquito-borne viruses belonging to the Flavivirus and Alphavirus genera. These viruses often cause non-specific or asymptomatic infection, which can confound viral prevalence studies. In addition, many acute phase diagnostic tests rely on the detection of viral components such as RNA or antigen. Standard serological tests are often not reliable for diagnosis after seroconversion and convalescence due to cross-reactivity among flaviviruses.

Methods: In order to contribute to development efforts for mosquito-borne serodiagnostics, we incubated 137 human sera on individual custom peptide arrays that consisted of over 866 unique peptides in quadruplicate. Our bioinformatics workflow to analyze these data incorporated machine learning, statistics, and B-cell epitope prediction.

Results: Here we report the results of our peptide array data analysis, which revealed sets of peptides that have diagnostic potential for detecting past exposure to a subset of the tested human pathogens including Zika virus. These peptides were then confirmed using the well-established ELISA method.

Conclusions: These array data, and the resulting peptides can be useful in diverse efforts including the development of new pan-flavivirus antibodies, more accurate epitope mapping, and vaccine development against these viral pathogens.
Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
Authors: Wu Kevin Z.L. , Jones Rebecca A. , Tachie-Menson Theresa , Macartney Thomas J. , Wood Nicola T. , Varghese Joby , Gourlay Robert , Soares Renata F. , Smith James C. , Sapkota Gopal P.
Published: February 2020

Background: Two recessive mutations in the FAM83G gene, causing A34E and R52P amino acid substitutions in the DUF1669 domain of the PAWS1 protein, are associated with palmoplantar keratoderma (PPK) in humans and dogs respectively. We have previously reported that PAWS1 associates with the Ser/Thr protein kinase CK1α through the DUF1669 domain to mediate canonical Wnt signalling.

Methods: Co-immunoprecipitation was used to investigate possible changes to PAWS1 interactors caused by the mutations. We also compared the stability of wild-type and mutant PAWS1 in cycloheximide-treated cells. Effects on Wnt signalling were determined using the TOPflash luciferase reporter assay in U2OS cells expressing PAWS1 mutant proteins. The ability of PAWS1 to induce axis duplication in Xenopus embryos was also tested. Finally, we knocked-in the A34E mutation at the native gene locus and measured Wnt-induced AXIN2 gene expression by RT-qPCR.

Results: We show that these PAWS1A34E and PAWS1R52P mutants fail to interact with CK1α but, like the wild-type protein, do interact with CD2AP and SMAD1. Like cells carrying a PAWS1F296A mutation, which also abolishes CK1α binding, cells carrying the A34E and R52P mutants respond poorly to Wnt signalling to an extent resembling that observed in FAM83G gene knockout cells. Consistent with this observation, these mutants, in contrast to the wild-type protein, fail to induce axis duplication in Xenopus embryos. We also found that the A34E and R52P mutant proteins are less abundant than the native protein and appear to be less stable, both when overexpressed in FAM83G-knockout cells and when knocked-in at the native FAM83G locus. Ala34 of PAWS1 is conserved in all FAM83 proteins and mutating the equivalent residue in FAM83H (A31E) also abolishes interaction with CK1 isoforms.

Conclusions: We propose that mutations in PAWS1 cause PPK pathogenesis through disruption of the CK1α interaction and attenuation of Wnt signalling.
Change Management
Authors: Chernikovskaya Marina , Chyemyezov Igor
Published: February 2020

The nature, the reasons, regularities, conditions and mechanisms of carrying out changes in the organizations are considered. Theoretical bases of professional and effective management of organizational changes are reflected: the objective regularities of changes in the organizations which are shown during their development; main objects and objects of changes in the organizations; value of the organizational context influencing the choice of technologies of management of changes and nature of development of changes; options and sequence of implementation of the operated changes in the organization; variety of possible technologies of management of changes;
approaches to the choice of strategy of implementation of changes and strategy; the main obstacles in implementation of changes; effective remedies and technology of overcoming of resistance to changes; stages of carrying out reengineering of business processes; introduction of quality systems in the Russian companies.
The textbook is intended for use when training bachelors in the Management direction 38.03.02, and also for all interested by problems of management of changes in the organizations.
The recovery strategy of the competitiveness of domestic aerospace industry
Authors: Barinov Vladimir
Published: February 2020

Issues of improving the management of the sector to restore competitiveness in three areas: the market, the financing system, the choice of projects of scientific and technological development. On the basis of the results of market research identified in terms of growth and shows promising directions of development domestic rocket and space industry. The developed model financial software industry, where a basis is state - private partnership. with an effective system of control by the investor. Criteria and methods to streamline the procedure for the selection of projects of scientific and technological development. Formulated the mechanism and conceptual basis of improving the economic mechanisms of the development of the RCP including the management of processes of commercialization of developments in the field.
Finance companies
Authors: Levchaev Petr
Published: February 2020

The textbook describes theoretical, methodological and practical bases of Finance companies. Logical structure of presentation allows you to consistently learn as the basic material of the course and the topics corresponding to the conceptual higher level of knowledge.
For a comprehensive assimilation of the provisions of the course "Finance organizations" topics of the discipline are given control questions and tasks for self-examination of knowledge of students, thesis topics and modern research directions of Finance of organizations and themes of final qualification works, questions to prepare for the exam, and recommended reading. Set out the problematic situation of Finance companies in the innovation economy.
Meets the requirements of Federal state educational standard of higher education of the last generation.
For students, postgraduates and teachers of economic specialties. Be useful to a wide circle of readers interested in the problems of Finance companies.
Imaginary Straight Lines in Cartesian Coordinate System
Authors: Korotkiy Viktor
Published: February 2020

A geometric model of imaginary conjugate straight lines a~b, allowing symbolic representation of these lines on the real coordinate plane xy is considered. In order to connect the algebraic and geometric representations of imaginary straight lines, it is proposed to use the “mark” formed by orthogonal d1 ⊥ d2 and main g1~g2 directions of the elliptic involution σ in the pencil V. The specification of two pairs of pulling apart each other real straight lines d1~d2, g1~g2 passing through V, uniquely defines the elliptic involution σ in the pencil V, therefore, the V(d1 ⊥ d2, g1~g2) mark completely defines a pair of imaginary double straight lines a~b of elliptic involution σ(V), that allows consider the mark as an “image” of these imaginary straight lines. When using a mark, it is required to establish a one-to-one correspondence between complex coefficients of imaginary double straight lines equations and a graphically given mark. The direct and inverse problems are solved in this paper. The direct one is creation a mark representing imaginary straight lines, given by its own equations. The inverse one is determination of coefficients for the equations of imaginary lines defined by the mark. The essence of the direct and inverse problems consists in establishing a oneto-one correspondence between the equations of imaginary double straight elliptic involutions σ in the pencil V, and a graphically given mark containing the orthogonal and main directions of this involution. To solve both the direct and inverse problems, the Hirsch theorem (A.G. Hirsch) is used, which establishes a one-to-one correspondence between the complex Cartesian coordinates for a pair of imaginary conjugated points and real coordinates of a special “marker” symbolically representing these points. Have been considered examples of solution for geometric problems involving imaginary lines. In particular, has been solved the problem of constructing a circle passing through a given point and touching imaginary lines defined by its mark V(d1 ⊥ d2, g1~g2). Has been proposed a graphical and analytical algorithm for determining the coefficients of equations of imaginary tangents, traced to a conic section from its inner point.
“Applied Geometry” Discipline Adaptation to Undergraduate for Exploitative Specialities of an Aviation High Educational Institution
Authors: Nazarova Olga
Published: February 2020

The problem of teaching and formulating the tasks for the “Applied Geometry” discipline is considered in this paper. Currently, in aviation high educational institutions there is a tendency to reduce the number of hours allocated to graphic disciplines; in addition, “Descriptive Geometry” – the habitual name of the discipline – has been replaced by name “Applied Geometry”. This is certainly connected with the transition to learning on undergraduate programs, that implies a competency-based approach, i.e., training in accordance with the necessary knowledge and methods of activity in a particular area [4; 9; 23; 29; 30; 34]. The planned results of learning in “Applied Geometry” include knowledge of methods for solving applied engineering-geometric problems, as well as the ability to use the basic elements of applied geometry and engineering graphics in professional activities, and to solve specific applied problems of geometric modeling [4; 14; 20; 22; 32]. For these reasons arises the question of the need to adapt “Descriptive Geometry” to the requirements and programs for the training of bachelors, bringing it to conformity with the name “Applied Geometry” of the discipline. According to the results of “Applied Geometry” studying, students ought to gain experience and have the ability to independently solve cognitive, organizational and other problems related to their future professional activities [28–30]. In this paper is proposed a general approach to the formulation of “Applied Geometry” problems for cadets pursuing a bachelor's degree in “Air Navigation” (25.03.03) and “Operation of Airports and Flight Support of Aircraft” (25.03.04). Using rather simple examples, has been considered the possibility to formulate the problem in such a way that instead of the traditional formulation it could be applied for a specific bachelor's degree. As well has been considered a complex applied problem, which is suitable as a task for performing a computational and graphic work, since it integrates several topics of the discipline.
Testing Technologies in Assessment of Students’ Substantive Readiness to Study Higher Educational Institution’s Geometric and Graphic Disciplines
Authors: Ignat'ev S. , Tret'yakova Z. , Folomkin A.
Published: February 2020

Engineering practice cannot and will never be successful without spatial imagination and thinking, deep knowledge of geometric methods and ways for solution of engineering problems, comprehensive understanding of specificity and geometric features of technical objects and their images, understanding of labor organization impact on these processes etc. In this paper has been described the social and pedagogical investigation of question related to students’ substantive readiness to study higher educational institution’s graphic disciplines, and this question’s basis is contradiction between requirements to the initial level of students’ knowledge and skills and the level of students’ substantive readiness on the course of school training. In this paper have been performed analysis and generalization of existing pedagogical experience on issues related to graphic training. A method and a scheme for monitoring the degree of students’ competence on the school geometry course using Google forms have been proposed. Selective testing of students by the proposed way has been performed. Statistical processing of data obtained during this testing has been carried out, the density function of correct responses has been built, field of testing results correlation with total score of Unified State Exam (USE) results has been carried out, cluster analysis of obtained results has been performed by Varda method. Using the theory of latent variables and the Rush model an analysis of test tasks, aimed at optimizing the test structure, has been carried out. Based on the performed investigation, recommendations have been given for further research in this field, and measures are proposed on changing the learning process aimed at personalizing and building an individual learning trajectory in order to increase the educational process’s efficiency.
Analysis of Some Problems from a Course on Theoretical Mechanics Solved by Descriptive Geometry’s Methods
Authors: Nazarova Olga
Published: February 2020

In this paper the usability of descriptive geometry’s methods for solution problems related to theoretical mechanics is considered. Descriptive geometry emerged as a science intended for solution the problems of human activity’s different branches. In connection with development of modern graphical means, the value of descriptive geometry is greatly underestimated, but it is on descriptive geometry’s principles and laws that have been built algorithms used in graphic applications [30]. For a long time descriptive geometry has been used by scientists in various spheres of human activity [27]. In study of general technical disciplines, interdisciplinary connections play an important role, especially between theoretical disciplines, whose understanding is particularly difficult for students [35]. Understanding the possibility of using descriptive geometry’s methods, students can think over aspects of their use in the performance of tasks under study, for example, theoretical mechanics. Methods, which can be use while solving problems from the course of theoretical mechanics, are learned by students in the standard course of descriptive geometry and are not particularly difficult. Therefore, the graphical approach to solving problems of theoretical mechanics is accessible and understandable for majority of successful students. In this paper example problems from the course of theoretical mechanics on the topics "Plane System of Forces" and "Spatial System of Forces" have been considered. Graphical problem solving was performed using the image of force vectors with the help of orthogonal projections. For checking the correctness of graphicalcons.
ASEAN is a driving force for regional integration in Asia
Authors: Khabriyeva Taliya , Shuvalov Igor' , Kapustin Anatoliy , Bevelikova Nelli , Kurbanov Rashad , Shvedkova Olga , Belyalova Asiya , Balkhaeva Sayana , Vasil'ev Leonid , Doronina Nataliya , Semilyutina Natalya , Zhuravleva Oksana , Pulyaeva Elena , Belikova Ksenia , Kasatkina Natalya , Kochnov D. , Baranchikova M. , Balychev Yu. , Boychenko A. , Gaidaenko Schaer Natalia
Published: February 2020

The book introduces the reader to the changing nature of integration processes in Asia under the influence of globalization. The analysis of factors that promote and hinder interaction between the ASEAN countries and non-regional partners of this Association is carried out.
The study describes the dynamic processes of economic integration within the framework of the Russia - ASEAN dialogue partnership and features of cooperation in various areas of legal regulation. The author reveals the mechanisms that influence the formation of a region-wide free trade zone for the ASEAN member States, and makes recommendations on priority areas of integration trends in Asia.
Particular attention is paid to the specifics of investment regulation in South-East Asia, harmonization of ASEAN legislation in the field of security, taxation, education, prospects for cooperation and legal mechanisms that ensure the implementation of further cooperation programs developed by the ASEAN member States.
For researchers, representatives of public authorities, as well as for anyone interested in the dynamics of integration processes in the Asia-Pacific region.
Financial management in small business
Authors: Morozko Natalya , Didyenko Valyentina
Published: February 2020

The textbook describes the main provisions of the financial policy of the organization. The features of small business functioning in Russia are highlighted. The problems of formation of financial resources of small organizations, insolvency of organizations, the financial equivalent of the security of small business functioning are revealed. The methods of financial management in small business, the provisions of the mechanism for ensuring financial stability of small organizations are considered in detail. The main directions of financial management for organizing the functioning of small organizations in the conditions of diversified financial services are systematically defined.
Meets the requirements of the Federal state educational standard of higher education of the latest generation.
For students and postgraduates studying financial management, as well as specialists and managers of organizations that need to make rational management decisions.
Business communication in the service: documentary, speech, branding, and advertising technologies
Authors: Nadyeina Tatyana , Goncharova Lyubov , Goykhman Oskar , Koshlyakova Mariya
Published: February 2020

Comprehensive study guide includes the basic content of a number of disciplines of the professional cycle, necessary for development of skills of referencing, annotating and composing business texts with the aim of providing intellectual services in the course of internal administration and promotion of the organization in the process of external communication.
Meets the requirements of Federal state educational standard of higher education of the last generation.
Designed for bachelors and masters in training areas "Service", "Advertising and public relations"; may be used when training in similar areas and obtaining additional education, as well as those who would like to work or works in the area of provision of services of an intellectual nature as administrators (secretaries and office managers), secretaries, assistants supervisor, speech writers or image-makers.
Psycho-correction work with families of children with disabilities
Authors: Tkacheva Viktoriya
Published: February 2020

In the educational-methodical manual deals with theoretical and conceptual frameworks, practical methods and techniques of psychological assistance to parents and other relatives of a child with disabilities.
The quality of teaching materials presented United by a common concept three technologies of psychocorrectional work with families of children with disabilities: methods of psychological assistance to families raising children with disabilities V. Tkachova; technology differentiated approach in the psychological work with parents of children with disabilities, developed by E. V. Ustinova; technology "Mozart" a systemic approach to family therapy N. P. Bolotova.
A teaching manual is addressed to psychologists, speech pathologists and other professionals working in the system, both General and special education, in social assistance centres for families and children, rehabilitation centres, health institutions which support the families raising children with disabilities. The book can be useful for teachers of preschool and school educational institutions, use of inclusive forms of education, and representatives of parent and of public associations.
Qualification murders
Authors: Goncharov Denis
Published: February 2020

In the scientific-practical guide analyzes the main provisions of the theory of qualification of crimes from the standpoint of the criminal, substantive and procedural law. Based on this, recommendations for the skill of killing, discusses the problem of correct assessment of the type of crime that occurs at different stages of criminal proceedings.
The manual is intended for the students trained on a speciality (direction) Jurisprudence, graduate students, researchers, practical workers of law-enforcement sphere.
Pedagogy of the camp
Authors: Borisova M.
Published: February 2020

Academic edition is a part of the educational complex consisting of a tutorial and workshop, which is designed to help the students in mastering of educational disciplines included in the undergraduate program, and teaching practice. The textbook discusses the history of the emergence and development of summer camps, presents materials that are necessary for the organization of work in children's camp: theoretical foundations of organizing the activities of counselors, guidelines for working with children of different age groups, the performance of the regime moments, forms and methods of organization of process of education in DOLLARS, etc. In the workshop the material presented on the organization of different activities of children and adolescents in the camp. The allowance is aimed at assisting the counselor in working with the temporary children's collective in the conditions of the camp.
The content of the textbook meets the requirements of Federal state educational standard of higher education of the last generation.
For students of higher educational institutions enrolled in the fields of study within the enlarged group "Education and pedagogy", as well as professionals of education and all those interested in problems of children's recreation and recuperation.
Pedagogy education: theory, methodology, technology, methods
Authors: Khodusov Aleksandr
Published: February 2020

The textbook discusses the theoretical and methodological problems of education, as well as its technologies and methods. Special attention is paid to the phenomenology of education and methodology, technology and methodology of its organization.
The textbook meets the requirements of the Federal state educational standard of higher education of the last generation in the disciplines of "Pedagogy", "Methods of training and education".
It is intended for bachelors studying in the direction of 44.03.01 "Pedagogical education", but it can also be useful for masters, graduate students, teachers-educators of educational organizations of various types.
The Pro-competitive manner as the Institute for the knowledge economy
Authors: Rozhdestvenskaya Elena
Published: February 2020

The monograph used the results obtained during the analysis of the Russian and foreign experience of state regulation of competition, legal and institutional securing of implementation of procompetitive policies. It is proposed the category of "Pro-competitive order" as an institution of the knowledge economy.
Recommendations principles for the formation of Pro-competitive policy of Russia in the aspect of the need for structural reformation of the economy of transition to economy based on knowledge.
The monograph is intended for students, teachers of economic universities and faculties, entrepreneurs, and anyone interested in the development of the knowledge economy in Russia and abroad.
A strategic model for the sustainability of agrarian business: the options, risks, solutions
Authors: Baryshnikov Nikolay , Samygin Denis
Published: February 2020

The monograph substantiates the parameters of the formation of the concept of sustainability of the agricultural economy, summarizes the tools of financial management of the agricultural sector. The analysis of liquidity and diagnostics of efficiency of agricultural business is carried out on the example of commodity producers in the region.the models of agricultural policy for managing financial resources and sources of their formation are based on them.
The investment attractiveness is assessed and the financial and economic risks of agricultural business are measured. Financial solutions have been developed to optimize sustainability in the context of recommendations for improving liquidity and stabilizing the efficiency of the agricultural business.
The publication is intended for managers and specialists of agribusiness management, researchers and teachers of higher educational institutions.
Small secrets of a big tomography
Authors: Fedorov Artem , Lavrent'eva Anna , Kononenko O. , Berezina Natal'ya
Published: February 2020

In recent decades, all over the world, new imaging technologies have been actively developed and introduced into clinical practice. In the proposed monograph, the monograph was collected and analyzed
Many years of experience in the use of magnetic resonance imaging
For medical imaging purposes.
This book is intended for doctors-radiologists and radiologists,
X-ray lab technicians and MRI operators, medical physicists, physicians
Clinical specialties, as well as for students of postgraduate departments and students of medical universities.
Strains of Spodoptera frugiperda (J.E.Smith) (Noctuidae) in the states of Paraná and São Paulo, Brazil
Authors: Richardt Francielly Silveira , Micheli Adriana , Tasior Daniele , Ruthes Elderson , Foerster Luís Amilton
Published: February 2020

Two strains of Spodoptera frugiperda (J.E. Smith) were first described in the United States; in Brazil, in the states of Rio Grande do Sul, Mato Grosso, and western Paraná they have also been reported. This study was aimed at identifying these strains in Norte Pioneiro and Campos Gerais, in the states of Paraná and southwestern São Paulo. Larvae of S. frugiperda were collected in the cities of Ponta Grossa, Tibagi, Arapoti, and Wenceslau Braz in Paraná, and in the city of Itaberá, in São Paulo. PCR-RFLP genotyping of the COI gene was carried out using sixty-six specimens. Based on their electrophoretic pattern, 51 individuals were identified as corn strain, five as rice strain, and 10 as hybrids (Rice in MspI and Maize in SacI). Our findings indicate that both S. frugiperda strains are present the study areas.
Depois de La Lys: as "Memórias da Grande Guerra", de Jaime Cortesão
Authors: Henriques João Miguel Henriques
Published: February 2020

Tendo-se recentemente assinalado o centenário do Armistício que pôs termo à Primeira Guerra Mundial, na qual a jovem república portuguesa participa com o entusiasmo heróico e ingénuo próprio da época, o presente artigo pretende apresentar e comentar algumas passagens da obra Memórias da Grande Guerra, de Jaime Cortesão, com particular enfoque no imediato rescaldo que faz da participação portuguesa, teoricamente vitoriosa. Nesta obra, o político, escritor e oficial português, além de passar em revista os momentos mais marcantes da sua desventura por terras da Flandres, enaltecendo em registo grandiloquente o heroísmo do soldado lusitano no terreno, procede igualmente a uma reflexão crítica sobre a forma como as elites políticas tratam os seus cidadãos mais esforçados e como nem sempre a memória oficial faz justiça aos sacrifícios empreendidos.
Adília do Outro Lado do Espelho (o lírico e o grotesco na poesia de Adília Lopes)
Authors: Ritterová Kateřina
Published: February 2020

Este breve estudo tem como objetivo seguir as vias e as variedades do humor na poesia da escritora portuguesa contemporânea Adília Lopes. A poética adiliana é muito específica: à primeira vista não é poesia ligada à beleza ou à ternura. A própria poetisa fala da sua poesia como de poesia prosaica ou poesia do quotidiano. O estudo mostra que a poética de Adília Lopes tem o seu lado de beleza e de ternura, já que desnuda a vida humana através do humor negro, mas de uma maneira benévola, se bem que de um lado que nem sempre queremos ver ou que pode estar longe de nos agradar. A análise seguirá as possibilidades da criação de situações grotescas e sensações de ternura e de horror, que causam riso e arrepio ao mesmo tempo. O trabalho está dividido em partes, segundo o modo como a poetisa consegue o efeito cómico – banalização dos chamados grandes temas: amor, morte e solidão, anedotas poéticas e banalização das obras literárias mitificadas. Na análise dos poemas escolhidos prova-se que a poesia de Adília Lopes, ainda que bastante crua e às vezes até cruel, possui um encanto inédito, muito próximo da poética de Alice no País das Maravilhas. Tanto das personagens de Alice como das personagens de Adília emanam certas características do grotesco, de forma simultaneamente lírica e feérica.
Formas de disjunção no haiku: algumas características do haiku em búlgaro e em português
Authors: Timenova Zlatka
Published: February 2020

O haiku, a forma poética mais breve, com origem na cultura japonesa, está a conquistar o mundo ocidental e a desafiar a crítica literária. O objetivo da nossa comunicação é analisar e comparar haiku de poetas búlgaros (M. Liubenova, P. Chuhov, M. Ribarova, etc) e de poetas portugueses (Luisa Freire, José T. Mendonça, Casimiro de Brito), com base no processo de disjunção de imagens que opera nas duas línguas. Assim, esperamos perceber como os poetas búlgaros e portugueses contribuem para a riqueza do haiku ocidental.
Maintaining Continuity in Service: An Empirical Examination of Primary Care Physicians
Authors: Ahuja Vishal , Alvarez Carlos A. , Staats Bradley R.
Published: February 2020

Problem definition: In many service operations, customers have repeated interactions with service providers. This creates two important questions for service design. First, how important is it to maintain the continuity of service for individuals? Second, because maintaining continuity is costly and, at times, operationally impractical for both the organization (because of potentially lower utilization) and providers (because of high effort required), should certain customer types, such as those with complex needs, be prioritized for continuity? These questions are particularly important in healthcare services where patients with chronic conditions visit primary care offices repeatedly. Therefore, we explore these questions in the context of diabetes, a chronic disease. Academic/practical relevance: Although the operations management (OM) and healthcare literatures suggest that higher continuity is better for health outcomes, the possibility that one could have too much continuity has not been explored. We draw on literature on continuity of care from the healthcare literature and learning effects from the OM literature to theorize and then show a curvilinear relationship. In addition, we further the literature on continuity by examining different categories for prioritization. Methodology: We use a detailed and comprehensive data set from the Veterans Health Administration, the largest integrated healthcare delivery system in the United States, which permits us to control for potential sources of heterogeneity. We analyze over 300,000 patients over an 11-year period who suffer from diabetes, a chronic disease whose successful management requires continuity of care, as well as kidney disease, a major complication of diabetes. We use an empirical approach to quantify the relationship between continuity of care and three important health outcomes: inpatient visits, length of stay, and readmission rate. We conduct extensive robustness checks and sensitivity analyses to validate our findings. Results: We find that continuity of care is related to improvements in all three health outcomes. Moreover, we find that the gains are not linearly improving in continuity, but rather the relationship is curvilinear, whereby outcomes improve and then decline in increasing continuity of care, suggesting that there may be value in having multiple providers. Additionally, we find that continuity of care is even more important for patients suffering from more complex conditions. Managerial implications: Identifying the amount of continuity of care to provide and determining which individuals to prioritize are both of interest to practitioners and policymakers because they can help in designing appropriate policies for staffing and work allocation.
Root Caries Part 1: an Overview of the Challenges
Authors: Burrows Stephen
Published: February 2020

The elderly population is increasing and they have a higher retention of natural teeth than previous cohorts. The increased prevalence of root caries in this group presents challenges to all those concerned in its management. In this article, aetiology, risk factors and diagnosis of root caries are discussed with the aim of implementing effective approaches in its management.

CPD/Clinical Relevance: Caries control should, when possible, be non-operative.
The novel coronavirus epidemic: How worried should we be?
Authors: Greener Mark
Published: February 2020

Mark Greener looks at the latest potential pandemic and what is known so far
Theory and Practical Procedure for Predicting S-N Curves at Various Stress Ratios
Authors: Kim Ho Sung
Published: February 2020

Predictive models in the past for stress ratio effect on S-N fatigue life have been subject to modifications since the 19th century. Many of them have been developed with limited experimental verifications or beyond the theoretical limit. Also, they have employed weak S-N curve models for the development, resulting in inefficiency in applications. There has been, also, a missing link in the development of predictive models between S-N curve behaviour and stress ratio effect. In this paper, theoretical analysis is presented and subsequently a practical procedure for predicting S-N curves at various stress ratio is proposed. The theoretical and experimental characteristics of the constant fatigue life (CFL) diagram were clarified for capability and limitations, and dependence of experimental fatigue behaviour. Mathematical relationships between linear CFL lines and fatigue damage parameters were successfully derived. As a result, the Kim and Zhang S-N curve model was successfully dovetailed with the linear CFL lines to predict S-N curves for the whole range of stress ratios. Theoretical predictions of fatigue life based on the mathematical relationships were verified with experimental data.