bluuebunny/crossref_metadata_2025 huggingface dataset:
LEKTUR KLASIK PENDIDIKAN ISLAM GENRE PSIKOLOGI
Authors: Nadia Mely , Ginting Lusinta Rehna
Published: February 2022

The discussion about the soul (al-nafs) in the Islamic world has been started since the emergence of Islamic thinkers on the historical stage. Beginning with the collapse of the Greek-Roman civilization and the movement of translation, commentary and original literature carried out by Islamic thinkers, especially during the Abbasid Daula, the essence of Greek thought was lifted and enriched. The development of psychology if traced through classical Islamic literature, it turns out that there is no separation of scientific disciplines. Psychology is better known as the science of the soul or ulumun nafs. The methodology used in this discussion is the search for references in the form of books and digitization. And the result is one of the Islamic leaders who study psychology, namely Abu Ali al-Khozin Ahmad Ibn Muhammad bin Ya'kub and better known as Ibn Miskawaih. The relationship between the human body and soul Ibn Miskawaih explains that under the soul there is the power of reasoning which is not preceded by sensory recognition. With the power of sensory recognition. The soul is able to distinguish between true or not related to the results of the production of the five senses. The difference is done by distributing sensory objects with one another. Ibn Miskawaih emphasizes the superiority of the human soul over animal souls with the power of thinking which is the source of behavioral considerations, which always leads to goodness.
PERSEPSI MASYARAKAT TERHADAP HIV/AIDS DAN ODHA SEBAGAI UPAYA UNTUK MENURUNKAN STIGMA MASYARAKAT TERHADAP PENDERITA HIV/AIDS DI DESA KREBET KECAMATAN PILANGKENCENG KABUPATEN MADIUN TAHUN 2016
Authors: NOERLIANI DONY
Published: February 2022

Penyakit HIV/AIDS merupakan issue sensitive dibidang kesehatan. Meskipun upaya untuk menekan laju kematian akibat AIDS dapat dikendalikan namun penemuan baru infeksi HIV dan kasus AIDS masih terus bertambah. Salah satu kendala dalam pengendalian penyakit HIV/AIDS adalah stigma dan diskriminasi terhadap penderita AIDS. Bila stigma dan diskriminasi dampak dari kesalahan persepsi tentang HIV/AIDS terus terjadi di masyarakat akan berdampak cukup signifikan terhadap penanggulangan HIV/AIDS. Tujuan dari penelitian ini untuk mengetahui persepsi masyarakat tentang HIV/AIDS dan ODHA di desa Krebet kecamatan Pilangkenceng Kabupaten Madiun. Rancangan penelitian yang digunakan adalah deskriptif. Populasi adalah warga desa Krebet Kecamatan Pilang Kenceng kabupaten Madiun dengan jumlah sampel 10 % dari jumlah populasi yang ada dengan criteria sampel yaitu warga desa Krebet yang dapat membaca dan menulis dengan rentang usia 17 tahun keatas. Teknik sampling yang digunakan Consecutive sampling. Penelitian dilaksanakan mulai bulan Februari sampai dengan bulan Agustus 2016. Instrument untuk pengumpulan data adalah kusioner. Data umum dianalisis dengan cara frekwensi jawaban dibandingkan dengan jumlah responden yang ada kemudian dikalikan 100 % dan hasilnya berupa prosentase. Data khusus dianalisis dengan score-T, persepsi dinyatakan positif (favorable) apabila nilai T ? Mean T dan persepsi dinyatakan negative ( unfavorable) apabila nilai T < Mean T. Persespsi masyarakat desa Krebet tentang penyakit HIV/AIDS pada sub aspek pengertian HIV/AIDS berpersepsi negatif, sub aspek penyebab penyakit HIV/AIDS berpersepsi positif, sub aspek cara penularan HIV/AIDS berpersepsi negatif dan sub aspek pencegahan HIV/Aids berpersepsi positif. Persespsi masyarakat desa Krebet tentang Odha pada sub aspek keberadaan Odha masyarakat Krebet berpersepsi positif dan sub aspek stigma terhadap Odha berpersepsi negatif. Bentuk stigma yang dilakukan masyarakat yaitu pernyataan bahwa Odha harus dijauhi (35,59%), pernyataan bahwa Odha harus diusir (29,12%), pernyataan bahwa Odha adalah orang yang tidak mampu untuk berkarya dan bekerja (38,53%), pernyataan bahwa Odha tidak perlu dilibatkan dalam kegiatan di masyarakat (38,55%). Masyarakat desa Krebet masih berpersespsi negatif tentang pengertian penyakit HIV/AIDS dan cara penularannya. Sebagian masyarakat desa Krebet masih mempunyai stigma negatif terhadap keberadaan Odha. Pemerintah setempat khususnya Dinkes kabupaten Madiun perlu melakukan penyuluhan dan sosialisasi yang intensif tentang HIV/AIDS sebagai upaya pencegahan dan penanggulangan penyakit HIV/AIDS dan sebagai langkah awal untuk memperbaiki stigma negatif dan diskriminasi terhadap Odha di kabupaten Madiun, mengingat desa Krebet termasuk dalam wilayah kecamatan Pilang Kenceng yang merupakan tiga besar kasus terbanyak penyakit HIV/AIDS di kabupaten Madiun.
A ROTINA NA EDUCAÇÃO INFANTIL
Authors: Conceição Eda Maria Sousa Matos da , Lopes Etiene Aparecida da Silva , Silva Jóici Pinheiro da , Agripino Joicy Laura da Silva , Ferreira Miriã Dias , Boazegevski Soraya
Published: February 2022

A rotina sempre esteve presente nas mais diversas organizações sociais, seja em qualquer nível político ou social há uma organização do tempo, o que também acontece no nível educacional. Para promover muito mais que uma orientação entre o espaço-tempo, a escola precisa estar relacionada com o meio ao qual se aplica, sobretudo no contexto pedagógico. A rotina na educação infantil sempre teve mais diversas significações e concepções ao longo do tempo, compreendida como disciplinadora das crianças, além de estruturante e significante para educadores e educandos. Esta trajetória tem sido compreendida e desenvolvida de várias perspectivas, sendo possível perceber, ao longo da existência das instituições de educação infantil, sua organização e sua função influências de diversas ordens: religiosa, filosófica, médica, psicológica e biológica, permitindo refletir e promover o conceito de rotina na educação infantil. Levando em conta essa trajetória histórica e as diferentes variações de hábitos no contexto educacional, neste artigo fizemos um resgate histórico relativos à educação infantil.
ALGORITMA CLUSTERING K-MEDOIDS PADA E-GOVERNMENT BIDANG INFORMATION AND COMMUNICATION TECHNOLOGY DALAM PENENTUAN STATUS EDGI
Authors: Mustofa Zaenal , Iman Saufik Suasana
Published: February 2022

Abstract E-Government is a tool to improve relations with the community, now the development of E-Government in various world governments are monitored directly by the UN through the United Nations E-Government Survey. This monitoring uses the framework where in this EGDI there are 3 factors considered: Online Service Index, Telecommunication Infrastructure Index and Human Capital Index. But the determination of EDGI status is less accurate because it must be based on knowledge and processing of the number of existing data so that required a calculation that applies clustering method with data mining techniques. Kmedoids using clustering techniques, capable of producing optimal Bouldin Index values and this study also determines the medoid distance calculation to obtain optimal algorithm, the value obtained from Bouldin Index on the Chebyshev K-medoids method 0.593. Thus, the optimal clustering scheme with distance ratio is the minimum index value of K-medoids Chebyshev.
SISTEM INFORMASI PENGELOLAAN PERSEDIAAN BAHAN BAKU BERBASIS CLIENT SERVER PADA CV. ALINEA JAVA SEMARANG
Authors: Rubhiyati Rini , Retno Lestianawati
Published: February 2022

Abstract The management of raw material inventory is a very important part for a company. In the process of inventory management of raw materials conducted on CV.Alinea Java until now still using conventional system using Microsoft Excel 2007, starting from material estimation, ordering process of goods to supplier, process of receipt and expenditure of raw materials, raw material returns, addressed to the leadership and related sections. And the utilization of wireless networks that are less effective because only connected computer warehouse administration and purchasing, not all users, to overcome the above problems, it is necessary information that utilizes the inventory management information system raw materials with computer network based client server using a new system of mutual terintregrasi all users so that all interested parties can access the desired data of course with certain restrictions, according to the status entered. Then created a system of inventory management information raw materials server client base on CV.Alinea Java by using Microsoft Visual Basic 6.0 and Microsoft SQL Server 2000 database that will assist in the process of data processing system.
ANALISIS RANCANG BANGUN KNOWLEDGE MANAGEMENT SYSTEM UNTUK MEMBENTUK SHARING CULTURE MATERI BAHAN AJAR BERBASIS WEB
Authors: Veliyanti Reni , Danny Manongga
Published: February 2022

Abstract The implementation of knowledge sharing with a system by sharing several web-based teaching materials, may be a solution for STEKOM needs. Lack of lecturers’policy and culture to implement knowledge management (knowledge sharing)of the web-based teaching materialsresulting in lecturer's knowledge cannot be shared well. The purpose of this research is for implementing knowledge management system as teaching material for improving the competence of STEKOM lecturers. This research uses the development of 10-step knowledge management roadmap method system made by Amrit Tiwana, 1999 and summarized into 4 phases, i.e.: 1. evaluation of infrastructure; 2. analysis, design and development of KMS; 3. deployment system; 4. evaluation of system design methods. Results of this research indicated that operation of the KMS has a great opportunity in terms of knowledge transfer by forming a sharing culture of web-based teaching materials on STEKOM. This constitute as an alternative for improving the teaching quality . Sharing of teaching material not only carried out in the internal environment of the STEKOM branch, but also among lecturers of STEKOM branch and between STEKOM lecturers and students
IMPLEMENTASI WEBSITE SEBAGAI MEDIA PROMOSI DAN INFORMASI PADA MAX Team OUTBOUND TRAINING UNTUK MEMUDAHKAN DAN MENINGKATKAN DAYA TARIK PELANGGAN
Authors: Rasminto Hendri , Danang Danang
Published: February 2022

Abstract The development of computer and internet science has covered the world community today. including companies and agencies around the world have internet facilities and websites as a form of promotion to the public. Likewise with MAX team Outbound Training Semarang, which continues to strive for improvement in its promotion program. To be able to provide convenience in promotional activities on MAX team requires a media campaign that is fast and can be accessed by the wider community. In this study concluded that the ease of accessing the website is very good, namely 81.67%. In addition, the attractiveness of consumers in accessing products online is also getting better, reaching 78.9%.
Analog Data Assimilation for the Selection of Suitable General Circulation Models
Authors: Ruiz Juan , Ailliot Pierre , Chau Thi Tuyet Trang , Le Bras Pierre , Monbet Valérie , Sévellec Florian , Tandeo Pierre
Published: February 2022

Abstract. Data assimilation is a relevant framework to merge a dynamical model with noisy observations. When various models are in competition, the question is to find the model that best matches the observations. This matching can be measured by using the model evidence, defined by the likelihood of the observations given the model. This study explores the performance of model selection based on model evidence computed using data-driven data assimilation, where dynamical models are emulated using machine learning methods. In this work, the methodology is tested with the three-variable Lorenz' model and with an intermediate complexity atmospheric general circulation model (a.k.a. the SPEEDY model). Numerical experiments show that the data-driven implementation of the model selection algorithm performs as well as the one that uses the dynamical model. The technique is able of selecting the best model among a set of possible models and also to characterize the spatio-temporal variability of the model sensitivity. Moreover, the technique is sensitive to differences in the model dynamics which are not reflected in the moments of the climatological probability distribution of the state variables. This suggests the implementation of this technique using available long-term observations and model simulations.
Penggunaan Mark Routing Untuk Melakukan Switching Jalur Akses Berdasarkan Prioritas Paket Data (Studi Kasus: Kantor PUSKUD JABAR)
Authors: Ramdhani Yudi , Mardhianto Riski
Published: February 2022

Jaringan komputer adalah hal yang sudah harus ada pada kantor-kantor saat ini, kebutuhan internet sangatlah tinggi untuk menunjang kegiatan maupun pekerjaan agar menjadi jauh lebih efisien. Di kantor yang terdapat banyak karyawan maupun sub bagian pastilah memiliki situasi kerja yang berbeda, meskipun telah ada limitasi pada setiap bagian maupun setiap komputer/device, namum tetap saja masalah kebutuhan bandwidth kadang masih tetap terjadi, entah itu dikarenakan banyaknya pengguna yang menggunakan jaringan tersebut maupun beberapa pengguna yang menggunakan jalur tersebut untuk internet demi menunggu pekerjaan berikutnya tiba. Dengan menggunakan Mark Routing memungkinkan mikrotik untuk memberikan sebuah tanda/mark pada setiap koneksi dan paket data yang lewat untuk nantinya dapat diatur sedemikian rupa saat melalui jaringan router tersebut, dalam penelitian ini dilakukan pemindahan koneksi yang menuju server dan akses website penunjang pekerjaan akan dialihkan menuju jalur akses gateway ISP2. Diterapkan pula data priority guna memprioritaskan jalur akses kepada paket data penting ketika banyak data melewati jalur akses yang sama dan penggunaan failover untuk mengatasi kegalalan koneksi ketika salah satu jalur akses mati. Dari penerapan 3 teknik diatas didapatkan hasil berupa thoughput yang jauh meningkat dan response time berkurang rata-rata sebesar 68,1% serta pengalihan gateway pada client ketika mengakses website tertentu yang telah ditentukan agar menuju gateway ISP2.

Kata kunci : Failover, Jaringan, Mark Routing, Prioritas Data,Switching.
Prediksi Keberhasilan Immunotherapy Pada Penyakit Kutil Dengan Menggunakan Algoritma Naïve Bayes
Authors: Arifin Toni , Syalwah Siti
Published: February 2022

Penyakit kutil merupakan masalah kesehatan kulit yang pada umumnya ditandai dengan munculnya benjolan kecil bertekstur kasar pada permukaan kulit yang disebabkan oleh virus yaitu Human Papilloma Virus (HPV). Salah satu teknik pengobatan penyakit kutil adalah Immunotherapy, metode ini merupakan pengobatan dengan meningkatkan sistem kekebalan tubuh untuk mengatasi penyakit kutil. Untuk mengurangi kesalahan deteksi dan menghindari keterlambatan diagnosis penderita penyakit kutil dapat dilakukan penerapan dan pemanfaatan teknik data mining. Salah satu metode data mining yang bisa dimanfaatkan adalah klasifikasi dan metode algoritma yang dapat digunakan untuk klasifikasi adalah algoritma Naive Bayes. Pada penelitian ini, algoritma klasifikasi data mining Naive Bayes diterapkan pada Immunotherapy Data Set. Setelah hasil penelitian diperoleh, terbukti metode data mining menggunakan algoritma Naive Bayes dengan 10-Fold Cross Validation menghasilkan nilai akurasi klasifikasi sebesar 81,11% dan nilai Area Under ROC (AUC) sebesar 0,63 yang termasuk kategori Good Classification.

Kata Kunci: Penyakit Kutil, Immunotherapy, Data Mining, Klasifikasi, Naive Bayes

ABSTRACT

Warts Disease is a skin health problem that is generally characterized by the appearance of small, rough textured lumps on the skin surface caused by a virus that is Human Papilloma Virus (HPV). One technique of treatment of wart disease is Immunotherapy, this method is a treatment by boosting the immune system to overcome the disease of warts. To reduce detection errors and avoid delays in diagnosing Warts disease, the application of data mining techniques can be applied and used. One method of data mining that can be used is classification and algorithm methods that can be used for classification are the Naive Bayes algorithm. In this study, the Naive Bayes data mining classification algorithm was applied to Immunotherapy Data Set. After the research results were obtained, it has been proven that data mining method using Naive Bayes algorithm with 10-Fold Cross Validation resulted in classification accuracy values ​​of 81,11% and Area Under ROC (AUC) values ​​of 0.63 which belonged to the Good Classification category.

Keywords: Warts Disease, Immunotherapy, Data Mining, Classification, Naive Bayes
Il cinema italiano del secondo dopoguerra e la controversa questione della discontinuitÃƒÂ : nuove strade, antichi territori?
Authors: Pitassio Francesco
Published: February 2022

The article focuses on the Italian cinema in building collective memory in post-war transitional phase. It tackles neorealist humanism and descriptive style, together with its obliteration of Fascism. These features contribute to Ã¢â‚¬Ëœcultural traumaÃ¢â‚¬â„¢: a symbolic activity reshaping collective identity. Finally, the article scrutinizes non-fiction works representing a contested area, in political and historical terms: Trieste. This final pace sheds light on the degree of diffusion of cultural trauma and clarifies how the concealment of Fascism operated as parapraxis.
Development and Characterization of Transdermal patches of Tramadol Hydrochloride: An Approach to Pain Management
Authors: Dhama Pooja , Kumar Sachin , Kumar Sagar Manoj
Published: February 2022

Transdermal drug delivery leads direct access to the systemic circulation through the skin which bypass drug from the hepatic first pass metabolism leading to increase bioavailability. Because Tramadol hydrochloride has low bioavailability, it was selected as a model drug. The present study was aimed to develop and characterize transdermal patches of Tramadol hydrochloride by solvent casting method. Two polymers Ethyl cellulose (EC) and Poly vinyl pyrrrolidine (PVP) in different combination or alone were used to form matrix system. Dibutylpthlate and Glycerine were incorporated as plasticizers. All the patches were characterized for parameters like Thickness, Weight variation, Drug content uniformity, Tensile strength, % elongation, folding endurance, moister content, In-vitro drug permeation study etc. Amongst all formulations, formulation F6 had more desirable characteristic & shows 82.82% drug permeation in 10 hr. Release kinetic can be described by Higuchi model with anomalous diffusion as a release mechanism. The Transdermal patch formulated from Ethyl Cellulose (EC) and PVP showed satisfactory physicochemical properties. So, it can be concluded that such a matrix type patches of Ethyl Cellulose (EC) and PVP could be a good carrier in transdermal delivery of Tramadol HCl. FTIR studies showed there were no incompatibilities between drug and other excipients.
Preformulation studies of Glipizide: First step towards developing stable Osmotic Drug Delivery System
Authors: Wani Manish , Rodge Pradeep , Baheti Akshay , Polshettiwar Satish , Nandgude Tanaji , Tamboli Firoj
Published: February 2022

Objective: The goal of this research study was to conduct a preformulation analysis of glipizide in order to establish a stable, robust as well as therapeutically effective system. Methods: Glipizide was characterized to determine its flow properties. Solubility was determined in different pH-varying solvents and its purity was determined by infrared spectrum and absorption maxima. Standard UV curve was developed to aid in further analytical research studies. Finally loss on drying (LOD) and drug-excipients compatibility tests were performed. Results: Glipizide has poor flow and compressibility properties (BD 0.222 g/ml, TD 0.425 g/ml, Carr’s index 47.78%, Hauser’s ratio 1.915). Solubility of drug was found to increase with increase in pH. The purity of drug was confirmed by infrared spectrum which showed characteristics peaks and by uv spectroscopy which exhibited maxima at 276 nm. The standard curve obtained was linear with correlation coefficient (R2 =0.998) and equation y = 0.0144x +0.0078. There were no drug excipient interactions which was clear as no visual changes in drug samples were observed with respect to discoloration, liquefaction and odor. Conclusion: The drug candidate under consideration was pure glipizide which had poor flow property suggesting use of granulation technique during tablet manufacturing and it was stable with selected excipient at reported ratio at 40oC / 75 % RH for 4 weeks.
Hydroquinone Solubility in Pure and Binary Solvent Mixture at Various Temperatures with FTIR
Authors: Aher Chandrakant S.
Published: February 2022

Gravimetric method is used to measured hydroquinone solubility in water, ethanol and in water+ethanol binary mixtures at temperatures (293.15, 295.15, 298.15, 300.15, 303.15, 305.15, 308.15, 310.15 and 313.15)K. Mole fractions solubility of hydroquinone are correlated with temperature by using the Apelblat equation. The combined nearly ideal binary solvent (NIBS)-Redlich-Kister equation is used to fit experimental hydroquinone solubility data in mixed solvents at constant temperature. ΔH0soln, ΔG0soln, and ΔS0soln are thermodynamic functions of hydroquinone in different solvents, obtained from the modified van’t Hoff equation. FTIR study is done for some hydroquinone solution.
Detection of SNPs in Merremia and its related taxa for species identification using DNA barcode markers
Authors: Satapathy Kamalakanta , Mohanta Omprakash , Jena Biswajit , Biswal Bhagyashree , Giri Alok Kumar , Acharya Laxmikanta
Published: February 2022

Merremiae is one of the least defined tribes in the family Convolvulaceae. It contains number of species which are basically herbs and shrubs. Species identification is a tedious work in the tribe using morphological characters as these traits are often influenced by environmental factors. In the present piece of work, we have analysed five taxa (Merremia umbellata, Merremia vitifolia, Merremia tridentata (Pubescens) and Merremia tridentata (Alatipes) along with one species of Ipomoea - Ipomoea calycina) with help of DNA barcode marker. We have used seven DNA barcoding regions from organellar DNA. Clear and reproducible amplifications were obtained in most of the cases but we failed to observe remarkable variation in amplified fragment size. Variations were detected in the DNA sequence associated with matK and rbcL loci. Sequence analysis showed visible difference between the intra and inter specific genetic distance based on K2P model for both the loci. From the sequenced data we found unique SNPs and In/Dels for the different taxa included in the study. Based upon the matK and rbcL SNP variance table, two dendrograms were constructed and authentication of species of Merremia and its relative were carried out. This work will help in authentic identification of the different taxa in the tribe Merremiae.
Ethyl Acetate and Butanol Fraction Effect of Citrus japonica Thunb. On Triglyceride Levels In Serum White Male Rats (Rattus norvegicus)
Authors: Djohari Meiriza , Mora Enda , Emrizal Emrizal , Angraini Cici , Aulia Fakhriyah
Published: February 2022

Hypertriglyceridemia is condition when there is an increase of triglyceride levels in blood. Hypertriglyceridemia can be increased blood pressure and heart problems. One of the plants can be used as a medicine is kasturi citrus peel (Citrus japonica Thunb.). This study aimed to determine the effect of giving butano fraction and ethyl acetate fraction of kasturi citrus peel (Citrus japonica Thunb.) to triglyceride levels on male white rats (Rattus norvegicus). The parameters are triglyceride levels in serum of male white rat induced with high-fat feed containing quail egg yolk (10 ml/kgWB). This research used 25 male white rats that divided into 5 groups with 5 rats per group. Normal groups are not given any treatment, only standard feed. The negative group was induced by high-fat feed and suspension Na CMC, the positive group was given high-fat feed and atorvastatin suspension 0,9 mg/kgWB and treatment group was given high-fat feed induction and suspension of ethyl acetate and butanol fraction of kasturi citrus peel with doses 250 mg/kgBW, as much 1% of body weight wich given orally. The triglyceride levels are calculating by using colorimetri enzymatic method with a photometer Mindray® (BA-88A) at wavelength 510 nm. The data percentage change in triglyceride levels on day 29 to day 15 obtained were analyzed with one-way Analysis of Variance (ANOVA) and continued with the Post Hoc Tukey test for each fraction. The results showed that giving butanol fraction and ethyl acetate fraction of kasturi citrus peel (Citrus japonica Thunb.) at doses of 250 mg/kg body weight had an effect on the decrease in triglyceride levels in serum of white male rat indicated by a significant difference (p<0.05) with negative control and showed a decrease in triglyceride levels activity that was not significant difference (p>0.05) with atorvastatin and there is no significant difference between anti hypertriglyceride activity of butanol fraction and ethyl acetate fraction (p>0.05)
Development and evaluation of nano herbosomes of Eleocarpus ganitrus for antioxidant activity
Authors: Joshi Gayatri , Tiwari Abhishek , Upadhyay Prashant , Tiwari Varsha
Published: February 2022

Aim: The conventional herbal extract of plant Eleoacarpus ganitrus have excellent in vitro bioactivity, but have poor effectiveness in vivo or in animal models, hence there is need for the development and evaluation of nano herbosomes of herbal extract. Material and method: Formulation of Herbosomes extract was prepared by using different ratio of Soya lecithin and cholesterol (F1 to F10). The method was selected on the basis of entrapment efficiency and availability of lab facility the best method was solvent evaporation method. Fourier-transform infrared study was performed to find out compatibilities between drug and polymers. Herbosomes was successfully prepared evaluated for drug content, drug entrapment, size, zeta potential, TEM, in-vitro drug release and in-vitro kinetics. Result: FTIR study shows no interaction between polymer and drug. Drug content and drug entrapment of optimized formulation F9 was found to be 93.6 % and 72 % with vesicle size 264.1 nm. In vitro release of herbosomes optimized formulation F9 show 80.33% release in 12 hr. in a sustained release pattern. The synergistic effect determined by free radical scavenging activity of herbosomal suspension by hydrogen peroxide model. In conclusion, herbosomes successfully prepared and encapsulated. It show extended release pattern with enhanced free radical scavenging activity by hydrogen peroxide model. The study shows that phospholipid-based herbosomes is a promising and viable strategy for improving the delivery of HS and similar phytoconstituents with low aqueous solubility.
Investigating the Anti-Viral and Anti-Bacterial activities of Jordanian Medicinal plants: A narrative review
Authors: Bajes Hana R. , Oran Sawsan A. , Al-Dujaili Emad AS
Published: February 2022

The diversity in Jordan’s flora due to its geographical areas make is well noted in the scientific literature. The challenge of disease and death caused by infectious diseases like viruses and bacteria, and as infectious diseases evolve and pathogens develop resistance to existing pharmaceuticals, the search for new novel leads, possibly with different modes of action, against bacterial and viral diseases has intensified in recent years. The intent of this review is to provide prevalent information on the antibacterial and antiviral potential in medicinal plants in Jordan, mode of action, type of viruses and bacteria, and phytochemical contents. It has been demonstrated by several studies presented in this review that medicinal plants in Jordan are rich in phytochemicals and possess antiviral and antibacterial properties.
Identification of bioactive ingredients in Chenopodium murale L Chenopodiaceae by HPLC and GC/MS
Authors: Mohasib Rasha M.M. , A. Nagib , Samad A.Abdel , Salama Zeinab A. , Gaafar Alaa A. , A.A. Hanan , Taie Taie , Hussein Sameh R.
Published: February 2022

This study aims to evaluate the successive extraction of the active ingredients and their antioxidant activity, anti-arthritic as well as anticancer activity of aerial parts (stem, leaves, and flowers) of Chenopodium murale L. Therefore, C. murale plants were extracted using four solvents with a wide range of polarities: n-hexane, ethyl acetate, methanolic and aqueous extracts. Chemical analysis proved it to be a potential source of protein, fat, carbohydrates, the results showed the percentages were: moisture content (92.45%), ash content (18.19%), crude protein (30.42%), crude lipid (2.86%), and carbohydrate (48.3%) respectively of the C.murale. Methanol extracts showed the highest content of total phenolic (TP), total flavonoid (TF), and total tannin (TT). The active ingredients were assessed as well employing gas chromatography coupled to mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC). The HPLC analysis of phenolic compounds confirmed that the methanol extract of C.murale detected high amounts of coumarin, 3, 4, 5 methoxy-cinnamic, and pyrogallol respectively. The ethyl acetate extract of C.murale herb displayed a rise cytotoxic effects on MCF7 (89.30 %), aqueous HCT116 (81%), methanol (60.70%) as well as n-hexane (39.80) respectively at 37°C for 48 h of exposure and concentration 100 µg/ml. In anti-arthritic activity at a dose-dependent, the Ethyl acetate successive fraction proved to be the most significant where it produced a percentage of inhibition ranging from 51.73 to 95.77 % followed by methanol fraction 47.70 to 90.02 % at (P ≤ 0.05), compared to Diclofenac as standard 91.22 to 96.44 %. Thus, our findings highlight the potential of this plant for its possible clinical use to oppose malignancy development against especially breast and colon cell lines with anti-arthritic effects as a bioagent in pharmaceutical industries.
Characterization of 4T Engine Oil Degrading Indigenous Bacteria Isolated From Semi Arid Zone of Rajasthan (Churu)
Authors: Sharma Shivendra , Pandey Pooja , Pathak Hardik , Dave Saurabh
Published: February 2022

The biodegradation potential of petroleum hydrocarbons such as polycyclic aromatic hydrocarbons (PAHs) and n-branched alkanes etc. of 4T engine oil were evaluated in aqueous media using bacterial strain isolated from petroleum contaminated soil of semi Arid region (Churu) of Rajasthan (India). Out of 12 petroleum hydrocarbons degrading bacterial strain one of the most growing bacteria was identified as Achromobacter xylosoxidans M66 by morphological, physiological, biochemical and partial sequencing of 16s rDNA. This strain was capable to degrade 68 ± 2% of n-alkanes, 28 ± 4% PAHs, and the abiotic loss was 20 ± 2% during 28 days incubation period. 64 ± 3% of n-alkanes and 26 ± 3% PAHs were biodegraded and abiotic loss during this period was 21 ± 3% in 35 days of incubation. As expected abiotic losses were decreases with increasing long chain alkanes and PAH’s concentration. Correlation between cell number and biodegradation rate showed that as the number of cell increased the degradation rate is also increased. The hydrocarbon contents were measured by Gas chromatography Mass spectroscopy (GC-MS) QP-2010 plus Shimadzu) carriedColumn-Rtx-5 MS, 30-meter X 0.25 mm i.d. X 0.25 μm film thickness, 1 ml/min; pressure 72.6 kPa and split ratio 10%. The initial temperature was 60ºC kept for 6 minutes and final temperature for 260ºC was kept for 20 minutes with total running time of 50 minutes.
Synthesis of Novel 6-(chloromethyl) - N2- (1 - (4-substituted phenyl) - 3-phenyl - 1H-pyrazol - 4-yl) methylene)-N4- aryl-1, 3, 5-triazine - 2, 4-diamine derivatives and their Antimicrobial Activity
Authors: Kushwaha Neelottama , Sharma C.S.
Published: February 2022

A series of 6-(chloromethyl)-N2-(1-(4-substituted phenyl)-3-phenyl-1H-pyrazol-4-yl) methylene)-N4-aryl-1, 3, 5-triazine - 2, 4-diamine 7(Aa-Gd) were synthesized using the appropriate synthetic procedure and characterized by spectral analysis. All the synthesized compounds were evaluated for their antibacterial and antifungal activities. The antibacterial activity was evaluated against Gram-positive strains (Staphylococcus aureus, Streptococcus aureus) and Gram-negative strains (Escherichia coli, Pseudomonas aeruginosa) using benzyl penicillin and streptomycin as standard drugs. Further, these compounds were studied for antifungal activity against three strains of fungi (Candida albicans, Aspergillus fumigate and Aspergillus flavus) using Ketoconazole as a standard drug. In the presented study all the synthesized compounds showed significant antibacterial and antifungal activities.
Integral representation of one class of entire functions
Authors: Khats' Ruslan
Published: February 2022

In this paper, we study an integral representation of one class of entire functions. Conditions for the existence of this representation in terms of certain solutions of some differential equations are found. We obtain asymptotic estimates of entire functions from the considered class of functions. We also give examples of entire functions from this class.
Encouraging a wider usage of software derived from research
Authors: Clément-Fontaine Mélanie , Di Cosmo Roberto , Guerry Bastien , Moreau Patrick , Pellegrini François
Published: February 2022

Software is a hybrid object in the world research as it is equally a driving force (as a tool), a result (as proof of the existence of a solution) and an object of study (as an artefact). This specific status means we need to define strategies, tools and procedures which are adapted to the various issues it raises. These include the citation of contributions to software design and production, the reproducibility of research results involving software and the wider usage and long-term sustainability of the software heritage created. This opportunity note by the Committee for Open Science's Free Software and Open Source Project Group describes the issues at stake and formulates actionable recommendations.
Effect of shading and high temperature amplitude on yield and phenolic contents of greenhouse capsicum (Capsicum annuum L.)
Authors: Phunchok Angmo  , Tsering Dolma  , Nawang Phuntsog  , OP Chaurasia  , Tsering Stobdan
Published: February 2022

Low temperature is one of the most important abiotic factor that restrict the optimal production of warm-season vegetables in the cold mountain regions. Studies were conducted to establish the possibility of growing capsicum, a temperature sensitive crop, in a naturally ventilated passive solar greenhouse with high temperature amplitude (25.2±2.5ºC). Despite the temperature fluctuation from 6.8±2.9°C at night to 38.6±4.1°C day temperature, flowering and fruiting were seen. The salable yield inside the greenhouse was 4.5 to 4.8-fold higher that of open field. Red shade net combine with the greenhouse technology significantly increased the intercellular CO2 concentration but affected the photosynthetic rate. Shading delayed flowering and 51-59% reduction in salable fruit yield. Total phenolic contents (TPC) and total flavonoid contents (TFC) of capsicum grown under open field and greenhouse were similar. However, shading reduced the TPC and TFC by 35.2% and 14.6%, respectively inside the greenhouse.
嵌入式教學對集中式特教班低口語自閉症學生科學探究學習成效之參與式行動研究
Authors: 吳雅萍 吳雅萍 , Ya-Ping Wu 陳明聰
Published: February 2022

研究者和兩所學校的特教教師與教師助理員組成行動團隊，分別在兩個集中式特教班進行一年參與式行動研究與個案研究。本行動研究設計一套具有理論基礎的嵌入式教學方案，內容包含精確教學和輔助溝通介入策略與訓練材料，希望解決兩位低口語自閉症學生在集中式特教班的團體科學探究課程所遭遇的學習困境。教學行動實施後也經歷了調整，包括特教教師在團體科學探究課程組織與教學調整，以及在嵌入式教學方案中，強化教師助理員介入輔助溝通的策略、回應提示策略和褪除程序。資料蒐集來源包括質性與量化資料，分析採持續比較法和描述性統計。從行動歷程與成果發現，嵌入式教學行動方案能促進兩位自閉症學生在團體科學探究課程的參與性，習得科學詞彙與定義，以及部分單元的科學成就測驗已達精熟。進一步分析未達精熟的測驗題型是與理解實驗變因、推論、類化等題型有關，但仍發現隨著介入的單元數量，而有進步趨勢。最後提出未來研究與實務建議。

 

Two researchers and two special education teachers and paraprofessionals from two self-contained classes conducted a participatory action research combined a case study for one year. Based on the evidence-based practice, the embedded instruction format contained ex-plicit instruction and augmentative and alternative communication was designed in the action plan. The purpose of the research aimed to investigate the effectiveness of embedded in-struction implemented within a science inquiry curriculum with group instruction for two autisms with low verbal function. After implementation, the action plan was also redesigned. The redesign process involved changes to the organization and teaching strategies in the group science inquiry curriculum for teaches, and a comprehensive training on augmentative and alternative communication, response-prompting strategy, and fading procedure for paraprofessionals. The source of data collection embraced the qualitative data and the quan-titative data, and was analyzed by a constant comparative method and descriptive statistical analysis. The results demonstrated the embedded instruction plan can be used to promote science learning of autisms in group science inquiry curriculum, including an increase in the autisms’ levels of participation in the group science inquiry curriculum and acquired science terms and definition from embedded instruction, and reached mastery in the scientific achievement test of some units. The error analysis showed the questions about experimental variables, inference, and generalization. However, the data also showed an improvement with the number of units introduced. Implications for practice and suggestions for future research are also discussed.

 
以家庭為中心專業團隊服務模式對早期療育之成效探討──以南部某一區域醫院為例
Authors: 徐敏 徐敏 , 劉萌容 劉萌容
Published: February 2022

以家庭為中心的服務觀念已是目前早期療育服務的發展重點，強調家庭與兒童皆為早期療育中重要的一環，臺灣的醫療服務模式多屬於傳統的專業導向，因此如何將專業服務邁向家庭中心導向凸顯出其重要性。本研究目的為建立可實施在醫療院所以家庭為中心早療專業團隊服務模式，並探討家庭與專業人員在進行研究過程中之變化與兒童之成效。專業團隊與九組家庭進行以作息為本位之晤談方式，透過討論形成共識，並在課程中持續與家庭討論與引導。結果顯示專業人員提供以家庭為中心的早療服務品質，在研究進行後皆有顯著的改善，家庭除了感受以家庭為中心的服務品質有顯著改善外，家庭成效則顯示在了解孩子優勢、幫助孩子學習以及獲得支持系統有顯著的進步；兒童在研究進行後在目標達成量表有顯著的進步。本研究所提出以家庭為中心的早療服務模式是可以運用在醫療環境中使用，相較於傳統的服務模式，能夠更符合家庭的需求，提升家庭的能力以及獲得更多具體的資訊來幫助孩子發展與學習，專業人員能夠在與家庭溝通的過程中更了解家庭的目標與期待，進而與家庭形成共識與良好的合作關係，進而達到良好的兒童成效。

 

The family-centered early intervention practice emphasizes that the family are as im-portant as the children with developmental delay when they receive the service, and the approach often adopts a professional team-based model. However, such practices may have difficulties in implementing in hospitals in Taiwan due to the traditional concept of “expert guidance” existing in most medical systems. The aim of this research attempted to build a professional team-based model and investigated the effects of family-centered services. There were nine families recruited in this study after trained by the professional team members on family-centered services courses which tried to build collaborative relationships with fami-lies, and coach families how to create learning opportunities for their children in daily ac-tivities. Instruments of MPOC-SP, MPOC, FOS-RT, CDIIT-DT and GAS were used to evaluate the effects of the team-based and family-centered services after six months inter-vention. The result found significant improvements in the quality of family-centered services provided by the professional team-based model. Another significant result was found in family outcomes, such as understanding rights, helping children learn and creating a support system for their own family. The outcomes of the children also showed significant im-provements in GAS. The study suggests the professional team-based model to provide fam-ily-centered early intervention services could be effective through collaboration for en-hancing functions of family and promoting development of children with special needs.

 
Análise de escolaridade das gestantes notificadas com sífilis no município de Fortaleza
Authors: Oliveira Lucas Fernandes de , Araújo Maria Alix Leite , Rocha Ana Fátima Braga , Oliveira Ana Karinne Dantas de , Félix Aline Sales Nunes
Published: February 2022

Introdução: O sistema de saúde vem enfrentando a sífilis como problema de saúde pública e econômica. Na gestação a infecção ocasiona uma série de malefícios para o bebê, tais como anemia, problemas ósseos, sendo necessária a internação e seguimento da criança. A notificação compulsória da sífilis auxilia no controle e no seguimento, viabilizando estratégias de prevenção. Em 2019, no estado do Ceará, foram identificados e notificados 3.169 casos, e em gestantes a taxa de detecção é de 18,4 casos/1.000 nascidos vivos, com o total de 2.337 casos. No município de Fortaleza (CE), entre os anos de 2015 e 2020, foram notificados 3.099 casos em gestantes, segundo registro do Departamento de Informática do Sistema Único de Saúde. Objetivo: Analisar o grau de escolaridade das gestantes notificadas com sífilis no município de Fortaleza. Métodos: Trata-se de um estudo epidemiológico descritivo e documental, retrospectivo à análise dos casos notificados/confirmados de gestantes com sífilis no período de 2015 a 2020 em Fortaleza. A coleta de dados se deu a partir do banco virtual de domínio público intitulado Departamento de Informática do Sistema Único de Saúde. Resultados: A prevalência encontrada foi de gestantes com ensino fundamental incompleto e com escolaridade ignorada, principalmente nos anos de 2017 a 2019. A maior frequência de escolaridade são dos 5º e 8º anos do ensino fundamental, que apenas no ano de 2019 tiveram 205 registros e, em 2020, 63. Todavia, neste mesmo período o mundo enfrenta uma grave crise sanitária por conta da pandemia do novo COVID-19. No total de casos desse grau de escolaridade há 758 casos, já em outros graus de estudo encontramos um número inferior. Conclusão: O baixo nível escolar pode ser conexo com a falta ou poucas práticas de saúde, logo mostrando-se um fator contributivo para a infecção da sífilis e, como consequência da não adesão ou não comparecimento ao pré-natal, levando a infecção para criança, desenvolvendo o fator congênito.
Como manter o tema infecções sexualmente transmissíveis/ aids na mídia no ano da pandemia da COVID-19
Authors: Santana José Almir , Matos Willian Bruno Couto de
Published: February 2022

Introdução: O tema pandemia da COVID-19 tomou conta das reportagens e dos noticiários da mídia e das redes sociais. Outros temas importantes, como as infecções sexualmente transmissíveis/aids, deixaram de ser prioridade para divulgação. Ficou bastante evidente a mudança de comportamento da sociedade. Tornou-se um desafio, manter o tema infecções sexualmente transmissíveis na mídia neste momento difícil. Objetivo: Manter como pauta durante todo o ano, principalmente no período da pandemia da COVID 19, na mídia de Sergipe, os temas ligados às infecções sexualmente transmissíveis/aids. Métodos: Foi elaborada uma programação de datas temáticas, além das datas já conhecidas, associadas direta ou indiretamente aos temas infecções sexualmente transmissíveis/aids: Dia Mundial da Tuberculose (coinfecção tuberculose-vírus da imunodeficiência humana), Dia internacional da Mulher (infecção do vírus da imunodeficiência humana e sífilis na mulher), Dia das Mães (importância do pré-natal), Dia dos Pais (o pré-natal do parceiro), Dia da Descoberta do Vírus da Imunodeficiência Humana, Dia da Descoberta do Primeiro Caso de Aids, Dia dos Namorados, Dia do Homem (saúde sexual masculina e infecções sexualmente transmissíveis), Dia do Sexo (incentivo ao uso do preservativo), Dia da Gravidez na Adolescência, Dia Nacional da Sífilis, Dia da Prevenção da Aids no Local de Trabalho, Dia da Criança e Dia da Criança Soropositiva (prevenção da transmissão vertical do vírus da imunodeficiência humana). Cada data é contextualizada com algum tema ligado às infecções sexualmente transmissíveis/aids. Há a produção de um texto que enviado para os principais órgãos de comunicação e para as redes sociais. Resultados: Os diversos órgãos de comunicação passaram a divulgar as 16 datas associando ao tema infecções sexualmente transmissíveis/aids. Mensalmente, a divulgação das datas vem gerando sugestão de pauta e reportagens interessantes na mídia sergipana, principalmente nas emissoras de rádio e televisão e nas redes sociais. Conclusão: Colocar na pauta dos meios de comunicação de massa o tema infecções sexualmente transmissíveis/aids o ano todo gera várias reportagens educativas. A mídia tem grande influência na mudança de interesses e de atitudes da população.
Profilaxia pré-exposição ao vírus da imunodeficiência humana em serviço de referência na capital do Piauí
Authors: Sousa Karinna Alves Amorim de , Araújo Welber Silva , Araújo Telma Maria Evangelista de
Published: February 2022

Introdução: A profilaxia pré-exposição ao vírus da imunodeficiência humana compõe estratégia da prevenção combinada. É um método de prevenção à infecção pelo vírus da imunodeficiência humana que consiste na tomada diária de medicação que impede infecção antes da exposição. Indicada para pessoas em maior risco de contrair o vírus da imunodeficiência humana. No Piauí foi implantada inicialmente no Centro de Testagem e Aconselhamento da capital em 2019. Objetivo: Caracterizar os usuários da profilaxia pré-exposição ao vírus da imunodeficiência humana atendidos no Centro de Testagem e Aconselhamento na capital no primeiro ano de oferta. Métodos: Estudo descritivo, quantitativo, transversal, realizado por meio do levantamento de dados dos indivíduos em uso da profilaxia pré-exposição no período de junho de 2019 a junho de 2020. Os registros foram provenientes de prontuários e do sistema de controle logístico de medicamentos. Foram realizadas análises de estatística descritiva simples. Resultados: Observaram-se 55 usuários, 91% homens; 42% tinham entre 26 e 35 anos, 62% eram pardos, 82% possuíam mais de 12 anos de estudo, 86% residiam na capital, 72,73% eram homossexuais, 70% buscaram a profilaxia pré-exposição pela imprensa, 35% já haviam usado a profilaxia pós-exposição pelo menos uma vez no ultimo ano, 86% mencionaram relações sexuais com até dez pessoas nos últimos três meses e 42% relataram usar preservativos em todas as relações sexuais, 20% não usam preservativos ou fazem de forma irregular. Quanto acompanhamento clínico, 66% retornaram ao serviço com 30 dias, 77% não apresentaram infecção sexualmente transmissível nos últimos seis meses, 75% continuaram usando a medicação e não apresentavam desconforto, 87% tomaram todos os comprimidos diariamente. Dos que sentiram desconfortos, 67% continuaram com a profilaxia e 33% abandonaram. Conclusão: Necessidade de descentralização da oferta a outros serviços, tendo em vista boa aceitabilidade com demanda inicial. Importância de criar estratégias para acompanhamento e monitoramento dos usuários para melhor qualidade na atenção. Divulgar aos profissionais de saúde para encaminhar usuários com indicação.