bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Penerapan Artificial Neural Network Algoritma Propagasi Balik untuk Meramalkan Harga Saham pada Bursa Efek Indonesia
Authors: Mahfuzh Muhammad Farhan , Yuliantari Risky Via
Published: July 2022

Investasi merupakan sebuah tindakan yang sangat penting dilakukan untuk mengamankan nilai mata uang terhadap inflasi. Instrumen investasi yang ditawarkan Bursa Efek Indonesia cukup beragam, salah satunya adalah saham. Saham merupakan bukti seseorang terhadap kepemilikan suatu perusahaan. Investasi saham juga memberikan hasil yang cukup tinggi, sebanding dengan risiko yang ada. Jaringan syaraf tiruan berfungsi untuk meramalkan harga saham sebagai acuan investor dalam menjual atau membeli saham. Metode backpropagation merupakan algoritma pembelajaran yang didalamnya terdapat layer tersembunyi untuk meningkatkan akurasi peramalan. Metode yang dilakukan adalah literature review jurnal penelitian terdahulu mengenai jaringan syaraf tiruan backpropagation. Peramalan dilakukan dengan software matlab ataupun aplikasi yang dibuat dengan memanfaatkan library matematika bahasa Python.  Dengan menambahkan faktor harga minyak bumi, analisis teknikal, fundamental dapat meningkatkan keakuratan peramalan harga saham. Tingkat akurasi tertinggi peramalan harga saham mencapai 99,98% dengan mean square error 0,0991. Arsitektur yang mudah digunakan dan memberikan nilai peramalan tinggi adalah dengan menggunakan software matlab
Estimation Precipitable Water Vapor Using (PWV) The Permanent Single GPS Station in Makasar and Bitung, Indonesia
Authors: Arief Syachrul
Published: July 2022

Meteorological investigations using global positioning systems (GPS) are based on permanent networks that are expensive to develop globally on Earth. In this study, it was confirmed that a single station GPS meteorology was feasible where there was no possibility for the development of a sophisticated, reliable GPS network. In Sulawesi, there are several GPS stations since 2009 GPS stations have been installed in Makassar and Bitung by the Indonesian Geospatial Information Agency, in which meteorological sensors are also installed in the station. GPS data is processed to estimate the total zenith delay (ZTD) of GPS signals in the troposphere. The ZTD estimate is then automatically converted to stored water vapor (PWV) using goGPS software. Two types of validation were applied to the PWV estimation. All of them proved the validity of the GPS results: (1) PWV was measured using radiosondes in Makassar and Bitung with almost the same climate regime, each showing a correlation of 96.5 and 83.0% with GPS PWV time series.  (2) a global reanalysis dataset was showing correlations of 60.1 and 75.3%, respectively, with GPS results. This validation shows that a permanent GPS network can be an alternative to get temporally more detailed and accurate meteorological data and lower costs and time-saving operations.
Alteration Characteristics and Precious Metal Availability in Gunung Gembes & Surroundings, Jeruk Village, Pacitan Regency, East Java Province
Authors: Hidayah Radhitya Adzan , Adi Prasetiya I Gusti Ngurah , Dzakiya Nurul Adzan
Published: July 2022

The research area is located in the area of Mount Gembes, Jeruk Village in Pacitan (East Java). This study aims to determine the characteristic and temperature in the formation of alteration which refers to petrography with the help of samples taken in the study area. The petrographic observations carried out were thin section observations which were then analyzed for the mineral content contained in the sample rock. After knowing the minerals contained in the sample rock, it is then entered into the mineral formation temperature diagram (White & Hedenquist, 1995). The method used in this study includes primary data in the form of geological observations such as lithology, geological structure geomorphology, environmental geology and alteration observations and combined with secondary data. Alteration observations in this study were carried out descriptively (megascopic) and subjective (microscopic). The geomorphic unit that works is of volcanic origin, with high hilly sub-units of porphyry dacite intrusion (volcanic neck). Geological structures that develop in the study area are faults, namely the left horizontal fault of Jeruk 1, the left horizontal fault of Jeruk 2 and the interpretation of the oranges right horizontal fault. Geological resources or sources found in the research area are mineral potential resources that are economical, and negative sources are in the form of mass movement of debris flow type. The Zonation and the type of alteration that developed in the research area are the clay alteration zone and silicification. The clay zone is formed at a temperature >100⁰C-220⁰C with a pH of 3-5 and a silicification zone is formed at a temperature>100⁰C-300⁰C with a pH <2 which is directly controlled by the faults found in the study site.
REKONSTRUKSI PELAPORAN KEUANGAN MASJID YANG DISESUAIKAN DENGAN SAK SEBAGAI WUJUD KELUASAN PERTANGGUNGJAWABAN (Studi Kasus pada Masjid Agung Baitul Mukminin Jombang)
Authors: Kurniawan Fitri Ahmad
Published: July 2022

This research aims to know and understand the process of reconstructing the mosque's financial statements in accordance with Financial Accounting Standards. Theory in this research is to use the Legitimacy Theory. This study uses a descriptive qualitative approach. The object of this research is the Great Mosque of Baitul Mukminin Jombang. The data analysis technique used to pattern matching techniques. The results showed that the reconstruction of the mosque's financial reporting preparation is made based on the accounting cycle, starting with the identification of transactions or accounts, then journalizing (general journal) to become financial statements in accordance with applicable accounting standards, taking into account the characteristics of the report in accordance with SAK
PENGARUH BUDAYA ORGANISASI, KEPEMIMPINAN, LINGKUNGAN KERJA DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN
Authors: Darmawan Arif
Published: July 2022

This study aims to examine whether there is an influence of organizational culture, leadership, work environment and work discipline on employee performance. This research is a causality research design with as many as 67 people as a sample who are employees of PT Citra Buana Prakarsa. The sampling method used was saturated sampling technique with a population of 67 people. The data analysis method used is multiple linear regression analysis method using the SPSS (Statistical Package for the Social Sciences) program version 25. The results of the test show that organizational culture has no effect on employee performance, while leadership, work environment and work discipline have a significant effect on employee performance. employee performance.
Pemetaan Situasi Skala Besar (1:500) Kampus Politeknik Negeri Batam
Authors: Rassarandi Farouki Dinda , Gustin Oktavianto , Irawan Sudra , Anurogo Wenang , Chayati Siti Noor , Pratama Rizki Widi , Putra Fajar , Aditia Rafly , Wandanita Melia
Published: July 2022

Peta situasi adalah peta topografi skala besar yang merupakan penyajian dari gambaran permukaan bumi baik detil alam maupun buatan manusia yang digambar pada bidang datar (kertas) dengan sistem proyeksi dan skala tertentu. Peta situasi dapat diperoleh dengan pemetaan terestris, yaitu proses pemetaan yang pengukurannya langsung dilakukan di permukaan bumi dengan peralatan ukur tertentu. Pembuatan peta situasi skala besar 1:500 Kampus Politeknik Negeri Batam (Polibatam) melalui pengukuran terestris dan penggambaran menggunakan teknologi digital. Tahapan dalam pembuatan peta situasi dimulai dengan pembuatan kerangka dasar pemetaan yang meliputi pengukuran Kerangka Kontrol Horizontal (KKH) dan Kerangka Kontrol Vertikal (KKV), kemudian dilanjutkan pada tahapan pengukuran titik-titik detil yang meliputi detil planimetris dan detil tinggi, penghitungan data hasil pengukuran, dan pembuatan peta secara digital menggunakan perangkat software pengolah SIG. Data hasil pengukuran diwujudkan dalam bentuk peta situasi skala 1:500 yang terletak di kawasan kampus Polibatam, Kelurahan Teluk Tering, Kecamatan Batam Kota, Kota Batam dalam layout kertas ukuran A3. Peta situasi ini memuat informasi tentang kontur atau elevasi, beberapa situasi tata ruang dan bangunan atau eksisting di kawasan kampus Polibatam yang digunakan sebagai dasar landscape kawasan untuk menunjang pembangunan gedung perkuliahan baru Polibatam. Berdasarkan dari hasil pengolahan data detil dan situasi ini terdapat kontur atau elevasi paling tinggi terletak di utara Gedung Utama Polibatam yaitu setinggi 40 m dpl dan elevasi paling rendah terletak di arah tenggara Asrama Putra Polibatam setinggi 34 m dpl, yang mana lokasi tersebut adalah rawa yang didasarnya merupakan tanah jenis lumpur.
Perancangan Mesin CNC untuk Pengerjaan Logam Aluminium dan Carbon Steel
Authors: Ridwan Ridwan , Utomo Wakhid , Yosevi Oki
Published: July 2022

Pada umumnya di dunia industri banyak menggunakan mesin CNC (Computer Numerically Control) yang sudah dapat mengolah pengerjaan logam berat seperti carbon steel. Hanya saja dalam penggunaanya membutuhkan biaya yang sangat besar. Untuk mengatasi hal ini perlu dirancang mesin CNC type router untuk pengerjaan logam aluminium dan carbon steel yang akan di operasikan pada PT. XYZ, guna meningkatkan efisiensi produksi dengan biaya yang relative sedikit. Sekarang ini perusahaan tersebut memiliki CNC type router yang hanya mampu memproses material resin, bakelite, durostone dan recocel, sedangkan pengerjaan material logam aluminium dan carbon stell masih menggunakan mesin milling konvensional. Dalam penelitian ini, dilakukan perancangan dan pembuatan mesin CNC router 3 axis yang dapat memproses material logam AISI 1046 carbon steel dan dapat diproduksi sendiri. Metode yang digunakan adalah merancang struktur dari mesin, dan melakukan pemilihan motor stepper sebagai penggerak sumbu axis x, y dan z. Hasil dari penelitian ini didapat mesin CNC router 3 axis dengan komponen elektronik yang sudah ditentukan, sehingga mempunyai rancangan torsi motor stepper sebesar 2,8 Nm. Mesin CNC router yang telah rancang mampu mengerjakan material logam AISI 1046 carbon steel.  Pada proses percobaan kedalaman pemakanan dengan menggunakan 0,2 - 1 mm/putaran dengan kecepatan penyayatan (feedrate) 200 mm/menit. Hasil pengukuran benda uji dari proses mesin CNC router yang dirancang tidak melebihi 0,2 mm. hasil pengukuran menggunakan standar toleransi japanese industrial standards (JIS) dengan metode pengukuran coordinate measuring machine (CMM).
Analysis of Cyber Security Knowledge and Skills for Capture the Flag Competition
Authors: T Jean Tirstan , A Joy Gilbert , Nelmiawati Nelmiawati
Published: July 2022

CTF (Capture The Flag) competitions have emerged as a pivotal instrument in development of cyber security education over the past six years. It is imperative to ensure that the CTF competitions continue to develop to facilitate growth of cyber security education. To achieve the desired growth, it is necessary to analyze the progress achieved in the last six years the program has been implemented. This research collects and analyzes approximately 500 CTF solutions from the CTFtime platform. From the results of this analysis, we have identified that skills and techniques are needed in each category of CTF questions. We use the results of this analysis as a reference for questions on the CTF Platform that we created during PCT (Polibatam Cyber ​​Team) regeneration. PCT consists of a group of students from the Cyber ​​Security Engineering study program who are prepared to be at the forefront in participating in various activities related to Cyber ​​Security. The method we use is different from other CTFs, in that we use a skill-based and technique-based approach. We found that this approach was able to attract 80% of participants in solving and improving their skills in Cyber Security towards any challenges in a competitive environment.
Identidad de Basanacantha inermis y B. wittii (Rubiaceae) y clave de las especies de Randia de la Amazonia brasileña
Authors: Salas Roberto M.
Published: July 2022

Como parte de la revisión de Randia para Sudamérica, se discute la identidad de dos especies amazónicas del género. Basanacantha inermis, descripta para Amazonia y conocida solo por el material tipo, es aquí reconocida como parte de la circunscripción de Randia. El uso del epíteto inermis se encuentra bloqueado en este género por uno anterior (Randia inermis Sessé & Moc.), por lo tanto, se provee un nuevo nombre, R. adolphoduckei. Basanacantha wittii, también reconocida hasta el presente solo por el tipo, es aquí considerada como nuevo sinónimo de R. hondensis. Se elige un lectotipo para B. wittii y un neotipo para R. hondensis. Se presentan descripciones completas para Randia adolphoduckei y R. hondensis, incluyendo datos de su biología y distribución. Se provee una ilustración de R. adolphoduckei detallando sus aspectos principales. Se presenta también una clave de las especies que habitan la Amazonia brasileña.
Aerobic Vaginitis: is Enterococcus faecalis Another Risk Factor in the Progression of Cervical Intraepithelial Neoplasia to Cervical Cancer—Literature Review
Authors: Jahić Mahira , Cerovac Anis
Published: July 2022

Objective: The aim of our review article is to show Enterococcus faecalis (E. faecalis) as a risk factor of cervical cancer. Mechanism: Aerobic vaginitis (AV) is the absence of a balance of vaginal flora containing aerobic and intestinal pathogens, varying degrees of vaginal inflammation and immature epithelial cells. The causes of AV responsible for inflammatory changes are: E. faecalis, Esherichia coli, group B streptococcus and Staphylococcus aureus. The pathogenic effect of aerobic microorganisms such as E. faecalis shows that it causes spontaneous abortion, premature birth, puerperal sepsis, abscesses, and urinary tract infections. Findings in Brief: AV caused by E. faecalis is more common in low-grade and high-grade cervical intraepithelial neoplasia (CIN) than in women with a normal Pap test and is thought to contribute to the progression of cervical cancer. E. faecalis produces hydrogen superoxide which causes chromosomal instability in intestinal epithelial cell infection, which is considered a key factor in the carcinogenic process. The presence of the Human papilloma virus (HPV) 16 gene and genome in E. faecalis in cervical cancer biopsy material leads to a specific link that may be a risk factor in the progression of CIN toward cancer. The presence of HPV in this bacteria can lead to persistent HPV infection, CIN development and progression to cervical cancer. Conclusions: Increased vaginal pH, lactobacilli deficiency, and the ability of E. faecalis to contain HPV-16 in episomal form in E. faecalis-induced AV could be key promoters of persistence and proliferation of cervical HPV as a risk factor in development of CIN and cervical cancer.
Transcriptome Analysis of Hepatopancreas Provides Insights into Differential Metabolic Mechanisms of Eriocheir sinensis Feeding on Trash Fish and Formulated Feed
Authors: Wang Meiyao , Liang Meng , Ge Jiachun , Ma Xingkong , Su Shengyan , Li Jianlin , Yu Fan , Li Hongxia , Song Changyou , Wu Ningyuan , Xu Pao , Tang Yongkai , Xu Gangchun
Published: July 2022

Background: The Chinese mitten crab, Eriocheir sinensis (E. sinensis), is a popular crab species in both domestic and foreign markets. Trash fish are essential for E. sinensis breeding, but have caused serious water pollution. The municipal party committee for the main production areas of E. sinensis implemented a ban on feeding on trash fish since 2020. Methods: In this study, we performed a culture experiment of E. sinensis feeding on trash fish and formulated feed, with comparative transcriptome analysis on hepatopancreas of E. sinensis. Results: The results indicate that formulated feed causes no significant difference in growth, survival rate or content of amino acids in the muscles of adult E. sinensis. Formulated feed caused a slight downregulation of pathways involved in amino acid metabolism, development, energy metabolism and homeostasis maintenance. Conclusions: On the whole, formulated feed can serve as an undifferentiated substitution for trash fish. This study provides a theoretical foundation for optimizing research on E. sinensis feed.
Inducible Heat Shock Protein 70 Levels in Patients and the mdx Mouse Affirm Regulation during Skeletal Muscle Regeneration in Muscular Dystrophy
Authors: Cosemans Gwenny , Merckx Caroline , De Bleecker Jan L. , De Paepe Boel
Published: July 2022

Background: Stress-inducible heat shock protein 70 (HSP70) is both a protective chaperone involved in protein homeostasis and an immune regulator. In both capacities, HSP70 has been implicated in muscle disorders, yet with fragmented and differing results. In this study we aimed to compare results obtained in the mouse model for the severest form of muscular dystrophy (MD) equivalent to Duchenne MD, termed the mdx mouse, with results obtained in human MD. Methods: Skeletal muscle and serum samples were obtained from 11 healthy controls, 11 fully characterized patients diagnosed with Becker MD and limb girdle MD (LGMD), and six muscle disease controls. In addition, muscle extracts were prepared from tibialis anterior of mdx and control mice at ages 4, 8 and 12 weeks. The HSP70 levels were quantified using RT-PCR, western blotting and protein arrays, and localized in muscle tissue sections using double immunofluorescence. Results: We found selective and significant 2.2-fold upregulation of HSP70 protein in mdx tibialis muscle at the earliest disease phase only. In LGMD and Becker MD patients, HSP70 protein levels were not significantly different from those of healthy muscle and serum. HSP70 was localized to regenerating muscle fibers both in mouse and human MD skeletal muscle tissues. Toll-like receptor (TLR) 2 and TLR4 expression was moderately increased on the sarcolemma in MD muscle, yet protein levels were not significantly different from normal controls. Conclusions: HSP70 upregulation in MD appears disease stage-dependent, marking the phase of most active muscle regeneration in the mdx mouse. We postulate that well-timed supportive therapeutic interventions with HSP70 agonists could potentially improve muscle tissue’s regenerative capacities in MD, attenuating loss of muscle mass while we await gene therapies to become more widely available.
Anxiolytic Effect of Satureja montana Dry Extract and its Active Compounds Rosmarinic Acid and Carvacrol in Acute Stress Experimental Model
Authors: Vilmosh Natalia , Delev Delyan , Kostadinov Ilia , Zlatanova Hristina , Kotetarova Maria , Kandilarov Ilin , Kostadinova Ivanka
Published: July 2022

Background: Anxiety disorders are an important not only medical, but also social problem, affecting approx. 300 million people worldwide in 2019. Medications used in the treatment of anxiety are associated with many adverse reactions, which explains the increased use of herbal products as anxiolytics. Methods: An anxiolytic activity of Satureja montana, rosmarinic acid and carvacrol after 14-day long administration on an animal model of acute stress was studied. For measurement of anxiolytic effect elevated plus maze, social interaction and Vogel tests were provided as well as examination of locomotor activity. Results: The dry extract of Satureja montana at both tested doses significantly increased locomotor activity as well as the time spent in the social recognition, compared to the control groups. The extract reduced the time in the closed arms and the proportion of entries into open arms to total entries and increased the time in the open arms of elevated plus maze compared to the positive control group. Likewise, rosmarinic acid and carvacrol increased significantly the time spent with a new congener in the social interaction test. Both compounds reduced the ratio of entries into open arms to total entries similarly to the dry extract of Satureja montana. Only rosmarinic acid increased the time in the open arms and reduced the time in the closed arms. Conclusions: Satureja montana at both experimental doses exerted a significant anxiolytic activity in almost all the tests employed for evaluating anxious behavior. Carvacrol and rosmarinic acid showed a moderate anxiolytic effect.
Gait Disorders and Magnetic Resonance Imaging Characteristics in Older Adults with Cerebral Small Vessel Disease
Authors: Zhao Ping , Gu Yumeng , Feng Wenjun , Xia Xiaoshuang , Tian Xiaolin , Du Yanfen , Li Xin
Published: July 2022

Background: This study aims to explore the features of gait disorders with cerebral small vessel disease (CSVD), and results from magnetic resonance imaging (MRI) with diffusion tensor imaging (DTI) were analyzed. Methods: The 139 patients with CSVD were divided into two groups by the Tinetti scale scores: the gait disorder (GD) group with a score <24 (63 patients) and the normal gait (GN) group with a score ≥24 (76 patients). A series of scales and 3.0T MRI with DTI were used to analyze the correlation between the abnormal gaits and imaging findings. Results: The differences in the Barthel Index, Unified Parkinson’s Disease Rating Scale part III, and Montreal Cognitive Assessment (MoCA) scores between the two groups were significant (p < 0.05), and there were significant correlations between MoCA and total gait scores (r = 0.201, p = 0.002). The GD group had a more degraded gait score, widened gait base, and degraded gait length than the GN group (p < 0.05). There were significant differences between the two groups (p < 0.05) in white matter (WM) hyperintensities (WMH) of the Fazekas scale grade 2–3 and lacunes. The GD group had a greater total MRI burden than the GN group (p < 0.05). In DTI parameters, the GD group had lower fractional anisotropy (FA) and higher mean diffusion (MD) values in WM tracts in many areas around the ventricles (family-wise error corrected, p < 0.05). Significant correlations were observed between FA and the total gait score (r = 0.467, p < 0.01), and also between MD and total gait score (r  = –0.422, p < 0.01). Conclusions: Patients with CSVD with gait disorders had more WMH of Fazekas scale grade 2–3, lacunes, and total MRI burden than the GN patients, and those with gait disorders may suffer from demyelination of nerve fibers and damage to the fibers’ microstructures.
Analysis of Clinical Features and Outcomes of Infective Endocarditis with Very Large Vegetations: A Retrospective Observational Study from 2016 to 2022
Authors: Cheng Xiaoyun , Meng Jie , Chen Yanqiu , Zhang Fan
Published: July 2022

Background: Cases of infective endocarditis (IE) with >30 mm vegetations are rare and are associated with high mortality. Clinical experience, clear therapeutic standards, and outcome evidence about these cases are still lacking. Methods: Detailed clinical data from patients suffering from IE complicated with >30 mm vegetations were collected from a hospital medical record system. Age- and sex-matched IE cases with 10–20 mm vegetations were used as a control group. Results: Twenty-two patients with >30 mm IE vegetations confirmed by biopsy and transthoracic echocardiography (TTE) were included. Thirteen (59.0%) patients had basic cardiac diseases, mainly congenital heart disease (CHD), rheumatic heart disease, and device-related issues. Fever (81.8%), heart murmur (86.4%), heart failure (86.4%), and embolism (50.0%) were common clinical manifestations and complications. TTE showed the diameter of vegetations was 34.5 (30.0–39.8) mm. The vegetations were usually accompanied by severe valvular regurgitation and pulmonary hypertension, and were most often located in the mitral valve (38.4%). Laboratory examinations indicated anemia, hypoalbuminemia, heart failure and inflammation. The rate of positive blood culture was 68.2%. Streptococcus viridans was the most frequent pathogen (26.7%). All individuals underwent vegetectomy and valve replacement or repair surgery, within 2 days of diagnosis. Compared with 10–20 mm vegetations group, >30 mm vegetations group had more complicated basic cardiac diseases, more special microbial infection, higher levels of procalcitonin (PCT) and D-dimer, more common heart failure and embolism. They received more biological valve replacements, and had longer intensive care unit length of stay (ICU-LOS). A few patients developed significant postoperative adverse events, including intracerebral hemorrhage (ICH), septic shock, and new symptomatic thrombosis. Re-exploratory thoracotomy was performed in two cases. All patients survived during 6-month follow-up without IE recurrence in >30 mm vegetations group, while there was one death and one recurrence in the 10–20 mm vegetations group. Conclusions: For IE complicated with >30 mm vegetations, clinical characteristics are diverse and vegetations on TTE are prone to misdiagnosis as thrombus or tumors. This article also emphasizes the use of >30 mm IE vegetations as an independent indication for early surgery to improve prognosis.
Yangxinshi Tablet Improves Exercise Capacity for Patients with Coronary Heart Disease: Results from a Randomized, Double-Blind, Placebo-Controlled, and Multicenter Trial
Authors: Zhang Sisi , Shen Yuqin , Liu Peiliang , Meng Xiaoping , Hu Dayi
Published: July 2022

Objective: To assess the clinical effectiveness of Yangxinshi (YXS) tablets on exercise capacity and symptoms of anxiety and depression in patients with coronary heart disease (CHD). Methods and Results: A randomized, double-blind, placebo-controlled, multicenter clinical trial was performed to assess the effects of YXS tablets on exercise capacity and quality of life in patients with CHD. A total of 82 patients were included in this trial. Compared with the placebo group, the YXS group showed significant improvement in peak VO2 (0.22 L/min vs 0.01 L/min; difference 0.1, 95% confidence interval (CI) 0.04–0.16, p = 0.000), peak Mets (0.58 vs 0.09; difference 0.3, 95% CI 0.12–0.47, p = 0.005), anaerobic threshold (AT) VO2 (0.23 L/min vs 0.04 L/min; difference 0.12, 95% CI 0.07–0.18, p = 0.000), AT Mets (0.62 vs 0.16; difference 0.35, 95% CI 0.2–0.5, p = 0.001), and 6 minutes walking test (6MWT) (50.05 m vs 11.91 m; difference 29.92, 95% CI 18.78–41.07, p = 0.000). There were no differences in Hamilton anxiety rating scale (HAM-A score (1.97 vs 2.07; difference 2.03, 95% CI 0.99–3.06, p = 0.926) and Hamilton depression rating scale (HAM-D) score (1.06 vs 1.7; difference1.42, 95% CI 0.24–2.6, p = 0.592). Conclusions: In patients with CHD, YXS tablets, compared with placebo, could improve exercise capacity, without beneficial effects on anxiety and depression symptoms.
The role of candidate gene polymorphisms for endothelial dysfunction and metabolic disorders in the development of cardiovascular diseases under the influence of production factors
Authors: Chistova Nadezhda P.
Published: July 2022

Endothelial dysfunction plays an important role in the pathogenesis of cardiovascular diseases. Genetic predisposition, metabolic disorders and other effects, including occupational hazards, can lead to the formation of endothelial dysfunction. The study aims to assess the role of polymorphisms of candidate genes of endothelial dysfunction and metabolic disorders in the development of cardiovascular diseases in persons with occupational pathology. Scientists have found that the carriage of certain alleles of polymorphisms G894T of the endothelial nitric oxide synthase gene, Lys198Asp and G8002A of endothelin-1, Met235Thr and Thr174Met of the angiotensinogen gene, -2548G/A, 19G/A and G2453A of leptin, 668A/G and Gln223Arg of the leptin receptor, determining the structure of proteins-markers of endothelial dysfunction and metabolic syndrome, as well as some production factors (exposure to vibration, exposure to vinyl chloride, mercury, fluorine and aluminum compounds), all these are in close connection with the development of cardiovascular diseases in persons with occupational pathology.
Improvement of mechanisms of detecting early signs of health disorders for preservation labor longevity
Authors: Bukhriayrov Igor V. , Kuzmina Lyudmila P. , Izmerova Nataliya I. , Golovkova Nina P. , Nepershina Olga P.
Published: July 2022

The main direction of the state social policy is to ensure the priority of preserving and improving the health of the working population as the most important productive force of society, determining the national security of the country and its economic development. On the background of the projected decline in the ratio of the population of working age and older than able-bodied, an important task is to prevent the development of occupational and other diseases, to reduce cases of early loss of ability to work. One of the indicators of the deterioration of the workers health is a significant weighting of the primary pathology detected, the predominance of chronic diseases leading to loss of working capacity. For a number of reasons, occupational diseases are more often detected in the late stages of development, when irreversible changes in the body already occur. Assessing the harmful effects of working conditions and reducing it to the level of acceptable risks allows you to preserve the professional health of employees, prevent the development of professional and production-related pathology. Especially important in this case is the examination of trained workers in order to identify early signs of exposure to harmful production factors, including preventing the development of their pronounced forms, conducting an examination of professional suitability and examination of the connection of the disease with the profession, early diagnosis of general somatic diseases as a predisposing and aggravating factor in the formation of occupational diseases. In workers who have been in contact with a harmful and(or) dangerous production factor for a long time, individual pathognomonic disorders are observed in the early stages, without the formation of a clearly defined clinical syndrome, which is not enough to establish a clinical diagnosis of the disease but suggests the development of early signs of a specific effect of the factor. Early detection of signs of occupational diseases is most effective and feasible in the process of periodic medical examinations of employees, including in occupational pathology centers, and should serve as a basis for subsequent therapeutic and preventive measures to reduce the risks of developing occupational pathology. Based on the results of the literature analysis, it should be concluded that there is a need for modernization and modification of preventive measures, which are the basis for creating conditions for preserving the health and longevity of the working population of the country Ethics. The study was carried out in compliance with ethical standards.
The influence of electromagnetic fields of industrial frequency on the male reproductive system
Authors: Kuzmina Lyudmila P. , Kisljakova Agata A. , Bezrukavnikova Lyudmila M. , Khotuleva Anastasia G. , Varakuta Aleksandra L.
Published: July 2022

Introduction. The safety of exposure to the population of a growing number of sources of electromagnetic fields everywhere, both in work and at home, has become a public health problem. This article presents the results of research on the study of the potentially adverse effects of electromagnetic fields of industrial frequency on the reproductive system of personnel of energy supply institutions. The aim of the study is to explore the possible adverse effects of electromagnetic fields of industrial frequency on the male reproductive system. Materials and methods. The object of the study was 144 employees engaged in the repair and operation of power grid facilities and 40 employees who are not exposed to electromagnetic fields of industrial frequency. To assess laboratory parameters, blood samples were taken, followed by determination of the levels of total testosterone, free testosterone and globulin binding sex hormones. Results. The subjects of the main group revealed a high incidence of prostatic hyperplasia and chronic prostatitis. The employees of the main group had lower concentrations of sex hormones (p<0.05) in relation to similar indicators of the control group. A negative correlation was revealed between the levels of total, free testosterone and sex hormone binding globulin with experience (r=-0.36 p=0.009; r=-0.264 p=0.06; r=-0.349 p=0.01, respectively). Limitations of the study. The study is limited by the number of highly trained workers exposed to electromagnetic fields of industrial frequency. Conclusions. The results of the study indicate the negative impact of electromagnetic fields of industrial frequency on the reproductive system of employees engaged in the repair and operation of power grid facilities. With an increase in the length of service of employees, a decrease in the concentration of globulin binding sex hormones, total and free testosterone was found. Among workers exposed to electromagnetic fields of industrial frequency, a high prevalence of prostate pathologies was revealed.
Ô nhiễm môi trường đang trở thành gánh nặng của nền kinh tế
Authors: Lê Phan Thị
Published: July 2022

Nền kinh tế Việt Nam đã có những bước phát triển ấn tượng trong vài năm trở lại đây, đặc biệt là mức tăng trưởng dương 2,91% năm 2020 trong khi thế giới phải đối mặt với cuộc suy thoái toàn cầu chưa từng có tiền lệ do đại dịch Covid-19. Tuy nhiên, đi cùng với sự tăng trưởng, bất cứ nền kinh tế nào trong đó cả Việt Nam đều phải đối mặt với những thách thức về môi trường và khí hậu khiến các nhà hoạch định chính sách phải cân đối và đưa ra lựa chọn phù hợp giữa tăng trưởng và môi trường.
'Tick, Tick, BOOM! Recent updates in the use of electronic cigarette technology as an illicit drug delivery system' - A multimodal review of how licit harm reduction devices are being co-opted into potential lethal weapons.
Authors: Dooley Caitlin A
Published: July 2022

The vaporization of illicit drugs can be traced back to ancient times, to snuff boxes with traces of psychedelic drugs in Aztec tombs and opium pipes being found in the remains of many great ancient Chinese societies. The advancement of e-cigarette technology has resulted in a new and novel way to vaporize drugs, and while nicotine vaping remains their primary use, meta-analysis of online forums and statistical analysis indicates this is trend which is increasing in popularity. This paper aims to provide an update on the state of e-cigarettes being used as an illicit drug delivery system, the potential public health consequences of this kind of appropriation and a toxicological assessment of the most popular drugs being vaporised. A systematic review of online dark web marketplaces and online drug forums have formed the basis of this review. It can be concluded that this is a growing area of public health concern and one which should be continued to be monitored closely, particularly with respect to Novel Psychoactive Substances due to their continued and abundant proliferation and lack of research with respect to their toxicological profiles.
बहुजन अवधारणा: वर्तमान और भविष्य
Authors: Ranjan Pramod
Published: July 2022

बहुजन साहित्य की अवधारणा के मौज़ूदा दौर का आरम्भ वर्ष 2011 के इर्द-गिर्द होता दिखता है। उस समय हम लोगों ने फारवर्ड प्रेस नामक मासिक पत्रिका में इसके सैद्धांतिक पक्ष को विकसित करने वाले लेख प्रकाशित करना आरम्भ किया तथा हर वर्ष अप्रैल में, जो कि फुले-आम्बेडकर के जन्मदिन का माह है; उस पत्रिका की ‘बहुजन साहित्य वार्षिकी’ का प्रकाशन आरम्भ किया। ऐसी पाँच वार्षिकियाँ प्रकाशित हुईं, जिनमें इस अवधारणा के संदर्भ में हिन्दी के अधिकांश महत्त्वपूर्ण लेखकों के विचार सामने लाये गये। इस क्रम में कुछ किन्तु-परन्तु के साथ लगभग सभी लेखक इस अवधारणा की आवश्यकता से सहमत थे। उन अंकों में अधिकांश लेखकों ने इसकी मूल्य-संहिता और साैंदर्य-शास्त्र को लोगों के सामने रखने की आवश्यकता पर बल दिया। हम देख रहे हैं कि ये चीज़ें अब समय के साथ-साथ पल्लवित हो रहीं हैं
Hybrid Machine Learning for Integrating Pedological Knowledge into Digital Soil Mapping to Advance Next-Generation Earth System Models
Authors: Miranda Rodrigo , Nobrega Rodolfo , Silva Estevão , Silva Jadson , Araújo Filho José , Moura Magna , Barros Alexandre , Souza Alzira , Verhoef Anne , Yang Wanhong , Shao Hui , Srinivasan Raghavan , Ziadat Feras , Montenegro Suzana , Araújo Maria , Galvíncio Josiclêda
Published: July 2022

Land surface and Earth System models require reliable soil maps to represent the influence of spatial variability of soil properties on ecosystem fluxes and storages. However, mapping soils using conventional in situ survey protocols is time-consuming and costly. We addressed the outdated spatial information on soil physico-chemical properties for a tropical region with a ~700-km longitudinal gradient of contrasting topography, climate, and vegetation (~98,000 km2; NE Brazil), by developing a novel hybrid machine learning framework and applying it to this region. This framework reduces prediction redundancies due to high multicollinearity by implementing a recursive feature selector algorithm for input selection; its core is composed of the Soil-Landscape Estimation and Evaluation Program (SLEEP) and a calibrated Gradient Boosting Model (GBM) capable of modeling the spatial distribution of soil properties at multiple and dynamic soil depths. The use of SLEEP and GBM allowed us to explain the spatial distribution of various soil properties and their environmental modulators. The model training and testing approach used six topographical, ten meteorological and two vegetation properties, and data from 223 soil profiles across the study area. Our models demonstrated a consistent performance with spatial extrapolations exhibiting r2 values of 0.79–0.98, and -1.39–1.14% percent bias. The properties related to topography and climate were dominating when estimating the number of soil layers, soil texture, and the sum of bases. Our framework features high flexibility and it is transferable to other tropical regions, while reducing capital investments and increasing accuracy when compared to traditional mapping protocols.
On Double Jeopardy: Race and Gender Explain Intersectional Subjective Stigmatization Likely Additively, and Possibly Projectively, but Unlikely Multiplicatively
Authors: Bai Hui , Campos Nick
Published: July 2022

Though racism and sexism are the two most common discrimination studied by researchers, it remains unclear how one’s race and gender jointly contribute to their experience of stigmatization. Five studies (total N=13,274) test and compare three approaches to this question: the additive approach (race ⇒ racial stigmatization; gender ⇒ gender stigmatization), the projective approach (race ⇒ gender stigmatization; gender ⇒ racial stigmatization), and the multiplicative approach (race×gender ⇒ gender/race/overall stigmatization). Overall, our findings consistently find evidence that supports the additive approach and disconfirms the multiplicative approach. For the projective approach, we found some support for it and discover an asymmetry (race ⇒ gender stigmatization; gender ⇏ racial stigmatization) that we consistently confirmed across the studies. Together, these studies clarify the theories of double jeopardy and contribute to our understanding of stigmatization experiences as a function of race and gender.
Blumenbeete für soziale Integration? Sozialarbeiterische Interventionen am Beispiel des Projekts Querbeet im Kontext von Exklusionstendenzen im urbanen Raum
Authors: Harter Laura Maren
Published: July 2022

Sozialarbeiterische Interventionen am Beispiel des Projekts Querbeet im Kontext von Exklusionstendenzen im urbanen Raum: Durch das Wachsen moderner Städte erhöht sich auch der Druck auf den angespannten Wohnungsmarkt. Menschen ohne festen Wohnsitz und mit Suchterkrankungen werden im urbanen Raum als abweichend markiert und aus sozialen Bezügen exkludiert. Anhand des Projekts Querbeet wird eine pflanzengestützte sozialarbeiterische Intervention dargestellt, die auf urbane Problemlagen reagiert und die Integration marginalisierter Bevölkerungsgruppen anstrebt.
The Effect of Diversification and Funding Decisions on Company Performance and Corporate Value with Good Corporate Governance (GCG) as Moderated Variable
Authors: Suchandiko Elmayola , Efni Yulia , Rokhmawati Andewi
Published: July 2022

This study aims to analyze the effects of diversification and funding decisions on company performance and value of companies with Good Corporate Governance (GCG) as a moderating variable in an industrial manufacturing company listed on the Stock Exchange (IDX) in 2013-2017. Sampling method using purposive sampling techniques and accounting 41 manufacturing industry companies. Samples were analyzed by using PLS. The results of this study indicated that diversification has no significant significant effect on firm value. Funding decisions have a significant effect on the value of the company. The company's performance significantly influences the value of the company. The funding decision has a significant influence on the company's value through indirect. Diversification has a significant influence on the company's value through indirect. GCG has no significant effect in moderating the influence of funding decisions on firm value. GCG has a significant effect in moderating the effect of diversification on firm value.Keywords: Diversification, Financial Decision, Financial Performance, Firm Value, Good Corporate Governance
THE EFFECTS OF EXCHANGE RATE AND INTEREST SENSITIVITY, MANAGERIAL OWNERSHIP, AND INSTITUTIONAL OWNERSHIP ON FINANCIAL DISTRESS
Authors: Refni Zumaira , Haryetti Haryetti , Fathoni Ahmad Fauzan
Published: July 2022

Financial distress is a situation where a company is unable to repay debts that are past due, both short-term debt and long-term debt. So that it can cause the company's operational activities to be disrupted and bankrupt. This study examines the effect of exchange rate sensitivity, interest rate sensitivity, managerial ownership, and institutional ownership on financial distress. The population in this study are all manufacturing companies listed on the Indonesia Stock Exchange from 2016 to 2018. From this population, this research used 62 manufacturing companies listed on the Indonesia Stock Exchange in the 2016-2018 period as samples. This research uses a logistic regression analysis method. The results showed that the variable of exchange rate sensitivity has a significant negative effect on financial distress. Interest rate sensitivity has a significant positive impact on financial distress, managerial ownership has no significant positive effect on financial distress, and institutional ownership has no significant positive effect on financial distress. This shows that companies need to pay attention to exchange rate sensitivity and interest rate sensitivity because of the higher the sensitivity level, the worse it will have on the company.
Starzenie się populacji. Aktywizacja, koprodukcja i integracja społeczna osób starszych
Authors: Gawron Grzegorz , Klimczuk Andrzej , Szweda-Lewandowska Zofia
Published: July 2022

The study is illustrative and theoretical in nature, as it was created on the basis of a review of the available literature on the subject (Polish and foreign). The publication is addressed both to scientists and students dealing with the subject of population aging, old age and the elderly, as well as to a growing group of practitioners interested in these issues, including politicians and decision-makers, representatives of public services, representatives of the media and non-governmental organizations.
The history of development of the rice varieties in the Agricultural Research Center “Donskoy”
Authors: Kostylev P. U. , Krasnova E. V.
Published: July 2022

The article provides a brief historical overview of research work on rice at the Agrarian Scientific Center “Donskoy”, from 1957 to the present. Rostov Region is located on the northern border of the rice distribution area. Therefore, the rice cultivated here must be fruitful, cold-resistant and guaranteed to ripen at these latitudes. Therefore, studies were started on this culture with the aim of adapting it to new soil and climatic conditions. The work was carried out in such areas as selection, seed production, cultivation technology (norms and terms of sowing, doses of fertilizers and stimulants, protection of plants from diseases, pests and weeds). The breeding work was headed by Kosarev N.I. (1957–1967), Sindetsky A.L. (1967–1977), Rossikhin V.P. (1978–1994), Parfenyuk A.A. (1994–2000), Kostylev P.I. (2000–2018), Krasnova E.V. (since 2019). Research on agricultural technology of rice was supervised by Parfenyuk A. A. (1977–2003) and Stepovoj V.I. (2003–2010). The technical work was carried out by a large team of researchers, laboratory assistants and workers due to the multiple turnover. In total, 26 varieties of rice were created and entered into the State Register of Breeding Achievements of the Russian Federation for the North Caucasian (6) and Lower Volga (8) regions: Donskoy 1, Donskoy 2, Donskoy 3, Donskoy 4, Donskoy 402, Donskoy 63, Don 22, Don 26, Zernogradsky, Primanychsky, Salsky, Budennovsky, Privolny, Razdolny, Kontact, Zlaty, Virazh, Boyarin, Svetly, Komandor, Yuzhanin, Kuboyar, Acoustic, Virasan, Pirouette, Kapitan, Argamak etc. 13 master's and 3 doctoral dissertations, 15 monographs and a large number of articles have been published.
Mapping the Skin and the Guts of Stories – A Dialogue between Geolocated and Dislocated Cartographies
Authors: Olmedo Élise , Caquard Sébastien
Published: July 2022

Cet article propose un dialogue entre la cartographie géolocalisée et la cartographie sensible, entre les cartes euclidiennes et les cartes libérées de toutes coordonnées géographiques, entre les pratiques cartographiques conventionnelles et alternatives. Ce dialogue a été rendu nécessaire par les nombreux défis que présentent la mise en cartes de récits riches, complexes et parfois extrêmement chargés émotionnellement : les récits de vie d’exilés rwandais. En cartographiant deux de ces récits à l’aide d’un logiciel de cartographie géolocalisée – Atlascine – et d’une série de cartes sensibles, nous avons été amenés à réfléchir aux potentiels et limites de ces approches. Ces deux approches ont en commun de respecter l’intégrité des récits représentés, ainsi que de reconnaitre l’importance de rendre le processus cartographique le plus transparent possible. Néanmoins, leur utilisation en parallèle révèle leurs différences ainsi que leurs complémentarités. Les cartes géolocalisées ont tendance à traiter et performer les récits comme des bases de données géographiques. Elles sont adaptées pour représenter ce qui est explicite, ce qui est exprimé, géolocalisable, c’est-à-dire ce qui se situe à la surface textuelle de ces récits, au niveau de leur épiderme. En revanche, la cartographie sensible tend à aborder le texte comme une entrée dans ces récits, dans leurs profondeurs, dans leurs entrailles. Libérées de toute contrainte euclidienne, les cartes sensibles performent et révèlent les dimensions plus intimes et personnelles de ces histoires, sans se départir du point de vue des porteurs de récits pour qui certaines choses peuvent être difficiles à exprimer. Le dialogue entre ces deux approches cartographiques met en évidence leur complémentarité indispensable pour cartographier non seulement ce qui se dit dans les récits, mais aussi ce qui y est enfoui.