bluuebunny/crossref_metadata_2025 huggingface dataset:
Lex Cryptographia: Legal Extensions to Smart Contract Breaches and Governance in Blockchain Systems
Authors: Musthafa Annas Rasid , Putri Rifda Yussriyyah , Farizki Alfaiza Akbar , Alma Shafanissa Aulya
Published: February 2025

The development of smart contract in a decentralized blockchain system raises various problems in the legal field marked by cases of smart contract violations such as the DAO, Parity Wallet, and PlayDapp cases. The breach of smart contract in the blockchain system affects the application and enforcement of conventional law in a virtual world that has no geographical jurisdiction. The limitations of conventional law in regulating the virtual world gave birth to various new legal concepts such as lex cryptographia and virtual state. This research aims to examine the expansion of law in blockchain systems and smart contract, especially in cases of breach of smart contract and the birth of new governance. This research uses doctrinal research methods with a case study approach and literature research. Based on the results of this research, the existence of smart contracts affects the legal expansion of their legitimacy and application as contracts that have legal force. Smart contract that have no ties to territorial jurisdiction give the parties to the smart contract complete freedom to regulate the settlement of contract violations, so that smart contracts become law, legal procedures, and punishment itself in carrying out its functions. In addition, the existence of smart contracts in the blockchain system also gave birth to lex cryptographia as a new law and a blockchain-based virtual state as a new governance model that is not limited by geographical areas.
Vehicle exhaust emissions in the light of modern research tools: synergy of chassis dynamometers and computational models
Authors: Zimakowska-Laskowska Magdalena , Kozłowski Edward , Laskowski Piotr , Wiśniowski Piotr , Świderski Andrzej , Orynycz Olga
Published: February 2025

Assessing vehicle emissions is crucial for understanding their environmental impact and developing effective emission reduction strategies. This article discusses modern research tools that combine traditional laboratory measurements on chassis dynamometers with advanced theoretical models. Probabilistic methods, including stochastic processes based on Markov and semi-Markov chains, are important tools for modelling driving cycles, considering the variability of road conditions and driver behaviour. The article also presents mathematical approaches to emission data analysis, considering both the states of the technical system and the transitions between them, which allows for precise modelling of real vehicle operating conditions. Ultimately, the synergy of experimental measurements with computational modelling offers a more complete and accurate tool for assessing pollutant emissions, which is crucial in global efforts to improve air quality.
ON THE WEAK SUBDIFFERENTIAL, AUGMENTED NORMAL CONES AND DUALITY IN NONCONVEX OPTIMIZATION
Authors: Bila Samet , Kasımbeyli Refail
Published: February 2025

This article studies the properties of the weak subdifferential for nonsmooth and nonconvex analysis studied. This study presents a formulation that is directly involved in convex analysis carried out in the nonconvex case. In this work, we present a theory that applies epigraphs to obtain augmented normal cones.

The perturbation function plays a crucial role in establishing optimality conditions. This study demonstrates that positively homogeneous and lower semicontinuous functions are weakly subdifferentiable. Moreover, under specific conditions related to the objective function, the constraint function, and the feasible set, we show that the perturbation function is positively homogeneous. Thus we obtain a zero duality gap condition by implementing conditions on the objective function, constraint functions, and the set S.
Desafios da iniciação à docência
Authors: Gurgel Iure Coutre , Costa Sandy Lima , Farias Isabel Maria Sabino de
Published: February 2025

O texto apresenta resultados de uma pesquisa ampla que buscou, por meio de uma pesquisa-formação, conhecer os principais desafios vividos por professores iniciantes cearenses e que afetam o exercício profissional da docência em seus primeiros anos. Fundamentados pelos princípios teórico-metodológicos da pesquisa autobiográfica (Delory-Momberger, 2016), sustentada pela pesquisa-formação (Josso, 2006) como dispositivo de pesquisa e de formação, desenvolveu-se um processo de formação em formato virtual, em virtude do contexto pandêmico, com professores da Educação Básica no Ceará. Os dados produzidos por meio de narrativas evidenciaram desafios relacionados ao ingresso na docência, às condições de trabalho, às relações interpessoais e à prática profissional. As narrativas dos professores iniciantes cearenses evidenciam os primeiros anos da docência como momento singular para o professor iniciante e que a participação em uma pesquisa-formação caracterizou-se como um dispositivo potente de indução desses docentes, distinguindo o diálogo, reflexões e partilhas como elementos basilares para o seu desenvolvimento profissional.
Transações de uma vida
Authors: Serrano Castañeda José Antonio , Ballesteros Leiner Arturo , Ramos Morales Juan Mario
Published: February 2025

Para explicar a transição de ser um profissional para o início da experiência de ser apenas mais um aposentado no sistema educacional mexicano em nível superior, recorremos expressamente à versão de Dewey da noção de experiência: transação. Envolve atividade de agente, dar e receber, pontos de vista sobre a realidade analisados pelos valores éticos e estéticos dos sujeitos da interação e negociação contínua dos sentidos da experiência. A experiência de um profissional não se esgota em um texto, mas oferece uma maneira pela qual o social e o cultural são materializados na assunção de uma trajetória formativa em um contexto especial, o sistema educacional mexicano, em temporalidades específicas, um membro da geração baby boomer, aqueles que impulsionaram o crescimento de nossas sociedades e participaram do nascimento de instituições.
Os fantasmas já eram tristes
Authors: Gomes Neto José Joaquim , Oliveira Julliana Rodrigues de
Published: February 2025

O texto propõe, em sua primeira parte, um cenário reflexivo acerca da problemática da catástrofe humana na lógica do antropoceno. Os passos narrativos percorrem o território do corpo e das relações entre presença e ausência, entre humano e não humano, entre pertencimento e deslocamento. Esse percurso inspirou o território para o ensaio visual da segunda parte, em que apresentamos quatro fotografias que compuseram o ensaio visual denominado “Desvanecer”, bem como a narrativa da experiência de realizá-lo. O Coletivo Bunker apresenta, através deste ensaio, a forma como tem refletido sobre as problemáticas da atualidade, valendo-se dos corpos dos(as) artistas postos em relação um com o outro, e nesse caso a relação é transbordamento.
Uma cozinha, as coxinhas, fofocas e as Minas Gerais
Authors: Figueiredo Marcos Paulo Magalhães de
Published: February 2025

Este ensaio tem por objetivo demonstrar tendo como fio condutor algumas fotografias a multiplicidade de tramas existentes no interior do espaço de uma cozinha. O ímpeto de registrar a feitura das coxinhas na cozinha de minha própria casa surgiu de forma repentina, espontânea e nem um pouco planejada. Foi apenas no meio do preparo das coxinhas, um quitute de suma importância para uma das mulheres retratadas, que pensei na possibilidade de registro antropológico das relações produzidas na cozinha. O dito popular “a ocasião faz o ladrão” serve para exemplificar como ocorreu o processo de confecção deste ensaio visual. Foi observando a forma como Marlene, uma amiga e antiga vizinha de minha mãe, fazia e modelava as coxinhas, que fui percebendo a riqueza de detalhes existentes na movimentação.
Proa
Authors: Vargas Júlia , Vilhas Jinx
Published: February 2025

É com grande satisfação que apresentamos o décimo quarto volume da Proa: Revista de Antropologia e Arte. Publicado no marco de quinze anos da revista e seguindo o modelo de publicação contínua, o Volume 14 conta com contribuições variadas nos formatos de ensaios visuais, audiovisuais e artigos, além de uma tradução. Temas como memória, representação, pertencimento, corporalidades e identidades foram alguns dos pontos chaves que podemos destacar em comum entre essas tão distintas abordagens e campos de pesquisa. Colocando, como sempre, a antropologia e as artes em diálogo, esta edição da Proa nos brinda com textos inéditos, originais e analiticamente diversos.
O papel das políticas estaduais de inovação no índice de inovação dos estados brasileiros
Authors: Lago Nicole Cecchele , Bender Rafaela Luisa , Pletsch Maria Eduarda Medeiros , Kohlrausch Laura Fernanda , Costa Bianca Tiburski Vaz , Reichert Fernanda Maciel
Published: February 2025

Este estudo examina a relação entre as políticas estaduais de inovação no Brasil e o índice de inovação dos estados sob a perspectiva dos sistemas regionais de inovação. A pesquisa é classificada como qualitativa exploratória e abrange políticas de inovação estabelecidas por meio de leis e decretos estaduais editados até 2017 e no período entre 2018 (ano em que o primeiro índice foi divulgado) e 2021, a fim de entender como as políticas promulgados nesse período potencialmente contribuíram para os índices de inovação dos cinco estados mais inovadores em 2021. Assim, as disposições legislativas sobre inovação dos 27 estados brasileiros foram classificadas e examinadas sob as dimensões estrutural, financiamento e interação. Como resultados, quatro achados que podem ajudar a explicar o avanço ou a manutenção da posição desses estados no ranking de inovação foram apresentados. O estudo oferece contribuições teóricas e práticas sobre políticas de inovação no contexto dos estados brasileiros.
Um modelo estrutural em rede para promover a Segurança Alimentar e Nutricional em territórios vulnerabilizados
Authors: Zangirolani Lia Thieme Oikawa , Mescoloto Samantha Bittencourt , Assumpção Daniela de , Pongiluppi Gabriela , Ribeiro Luiza Failla , Teixeira Aline Rissatto , Chahin Carla Bueno , Arguelhes Bruna Pitasi , Gentil Patricia Chaves , Domene Semíramis Martins Álvares
Published: February 2025

Introdução: As Cozinhas Solidárias (CSol) no Brasil surgiram da organização social, com especial participação de agricultores familiares, do Movimento dos Trabalhadores Rurais Sem Terra (MST), e do Movimento dos Trabalhadores Sem Teto (MTST), em resposta à situação da fome agravada no período pandêmico. Elas atuam como porta de entrada ao acolhimento de pessoas vulnerabilizadas. Objetivo: Apresentar a estrutura de projeto de pesquisa que visa elaborar um modelo estrutural intersetorial em rede e uma matriz educativa dialógica para promover a SAN em territórios vulnerabilizados, considerando o abastecimento de alimentos e a formação de equipes de CSol. Métodos: Equipe formada por gestores públicos, integrantes do MST, MTST, CEAGESP e pesquisadores, pretende construir um diagnóstico situacional sobre as condições estruturais físicas, territoriais e humanas, identificar a procedência dos alimentos, estudar o planejamento, o preparo e a distribuição de refeições, identificar os alimentos produzidos por agricultores familiares, associações, cooperativas e assentados parceiros, e a contribuição das centrais de abastecimento e bancos de alimentos loco-regionais. Serão empregados: pesquisa de dados públicos, problematização segundo Maguerez; observação participante e grupos focais, na perspectiva da pesquisa cidadã. Para determinar a amostra e os multimapas, serão utilizados recursos de Inteligência Artificial e de geoprocessamento. Resultados: Será proposto um modelo para aplicação nos municípios brasileiros que contribuirá para as ações e políticas de promoção da SAN. Conclusão: Este relato de experiência apresenta o referencial teórico e o processo de construção do projeto para fortalecer a CSol como uma tecnologia social para promoção da Segurança Alimentar e Nutricional em territórios vulnerabilizados.
Great Eurasian Partnership and the Prospects of Development of the EAEU
Authors: Pyzhikov N. , Aliev T. , Zhivalov V.
Published: February 2025

The article considers the Great Eurasian Partnership (BEP) at the level of the global structure of the world order, as an alternative pole of development capable of competing with Western dominance and a system of values. The research used methods for assessing economic effects using a gravitational model, a graph construction and analysis technique, an analysis of legal documents, a quantitative and qualitative analysis of media reports. The results show that despite the fact that BEP has been in public circulation for quite a long time, it has not received an institutional content. In this regard, the BEP does not have an institutional form, therefore, interaction with institutionalized integration associations is extremely necessary for its development. At the same time, in fact, the BEP can become the basis for coordinating actions between other significant integration associations in the region. It is shown that the EAEU countries, despite the fact that, in general, they have formed a common agenda of topics and areas of cooperation, their strategic documents potentially contain much more topics and areas of development than are currently being implemented. The key directions and prospects of Russia in relation to the development of the BEP project are revealed. The analysis shows that in the context of geopolitical turbulence and the avalanche-like imposition of sanctions by unfriendly countries against two of the five EAEU member states, it seems advisable to expand the list of priorities of the EAEU activities to those aimed not so much at recognizing the fact of the formation of the Union and its positioning on the world stage, but also at promoting the interests of the EAEU within the framework of negotiations on the current the international agenda. It is proposed that, in order to improve the organization of international economic and social processes, the EAEU countries develop additional measures to the specific content of this initiative.
Co-inoculation of a pectinolytic Aureobasidium pullulans strain and Saccharomyces cerevisiae for low-temperature red fermentation: A strategy to enhance the colour and sensory properties of Malbec wines
Authors: Merín María , Martín María , Carrión Raúl , Morata Vilma
Published: February 2025

Low-temperature fermentation is employed to improve aroma production and retention in red wines but at the expense of polyphenol and pigment extraction. In this study, the strategy of co-inoculating the pectinolytic strain Aureobasidium pullulans GM-R-22 with a commercial Saccharomyces cerevisiae for the low-temperature fermentation (LTF, 17.5 °C) of Malbec red grapes was evaluated at pilot scale, and compared with a traditional fermentation (TF, 25 °C), to compensate for the lower extraction of colour and polyphenols at low maceration temperature. The effects of this strategy on the chromatic, phenolic, technological, antioxidant and sensory properties of Malbec wines were assessed during fermentation and up to 12 months of bottle storage. A. pullulans (Ap) grew and remained viable during 4 days of LTF, without affecting the fermentation and growth kinetics of S. cerevisiae (Sc), and significantly higher levels of pectinase activity (about 4.5-fold) were detected in LTF (Ap + Sc) compared to LTF (Sc) and TF (Sc) vinifications. At the end of the fermentation, LTF (Ap + Sc) wine showed higher colour intensity (CI), total anthocyanins (TA), total polyphenolic index (TPI) and a* with a lower L*, b* and filtration time (25 %) than LTF (Sc) wine. After 12 months of bottle storage, CI, TPI, TA and monomeric, copigmented and polymeric anthocyanins were significantly higher in LTF (Ap + Sc) than in LTF (Sc) and statistically equal to TF (Sc), although the CIELAB parameters and the antioxidant activity showed no statistical differences compared to control wines. Sensory analysis showed that the LTF (Ap + Sc) wine had greater colour intensity and violet hue than the LTF (Sc) wine, reaching the colour attribute scores of the TF (Sc) wine, and was particularly characterised by a spicy aroma, unlike the wines fermented in the absence of A. pullulans. This is the first study to demonstrate the performance of A. pullulans in pilot-scale fermentation and the efficiency of its pectinases in improving the extraction and stability of red wine colour fermented at low temperatures, approaching or achieving the levels of chromatic and phenolic parameters of the traditionally fermented Malbec wine.
Comprehensive review: sensor technologies, instrumentation, and signal processing in low-power IoT
Authors: Gazis Alexandros , Papadongonas Ioannis , Andriopoulos Athanasios , Zioudas Constantinos , Vavouras Theodoros
Published: February 2025

This article provides a comprehensive overview of sensors commonly used in low-cost, low-power systems, focusing on key concepts such as the Internet of Things (IoT), Big Data, and smart sensor technologies. It outlines the evolving roles of sensors, emphasizing their characteristics, technological advancements, and the transition toward “smart sensors” with integrated processing capabilities. The article also explores the growing importance of mini-computing devices in educational environments. These devices provide cost-effective and energy-efficient solutions for system monitoring, prototype validation, and real-world application development. By interfacing with wireless sensor networks and IoT systems, mini-computers enable students and researchers to design, test, and deploy sensor-based systems with minimal resource requirements. Furthermore, this article examines the most widely used sensors, detailing their properties and modes of operation to help readers understand how sensor systems function. The aim of this study is to provide an overview of the most suitable sensors for various applications by explaining their uses and operation in simple terms. This clarity will assist researchers in selecting the appropriate sensors for educational and research purposes and in understanding why specific sensors were chosen, along with their capabilities and possible limitations. Ultimately, this research seeks to equip future engineers with the knowledge and tools needed to integrate cutting-edge sensor networks, IoT, and Big Data technologies into scalable, real-world solutions.
Financial Performance as Mediator: The Role of Corporate Social Responsibility, Audit Quality, and Financial Distress in Islamic Finance Tax Aggressiveness
Authors: Suhadi Suhadi , Januarti Indira , SET Fuad , Hardiningsih Pancawati
Published: February 2025

This study aims to examine the influence of Corporate Social Responsibility (CSR), audit quality, and financial distress on tax aggressiveness with financial performance as a mediating variable. This research employs quantitative methods with a sample size of 168 companies listed on the Indonesian Sharia Stock Index (ISSI) from 2020-2022. Data were processed using multiple linear regression, and Sobel tests for mediation analysis. The results show that CSR and audit quality have a significant positive influence on financial performance. Meanwhile, financial distress has a significant negative effect on tax aggressiveness. CSR has a significant negative influence on the Effective Tax Rate (ETR). Audit quality has a significant positive influence on ETR, and financial distress also has a significant positive effect on ETR. Meanwhile, financial performance has not been proven to mediate CSR against tax aggressiveness. Theoretically, these findings suggest that financial performance is not a significant channel for understanding how CSR affects tax aggressiveness. In practical terms, this means that when a company conducts CSR activities, its impact on the tax strategy is not mediated by how well the company performs financially.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 22.02.2025 г. по 28.02.2025 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир
Published: February 2025

В обзоре представлен анализ эпидемиологической ситуации в странах мира по COVID-19 за неделю с 22.02.2025 г. по 28.02.2025 г.
Rate of Osteonecrosis After Femoral Lengthening with Intramedullary Lengthening Nails
Authors: Dubin Jeremy A. , Swartz Gabrielle N. , Bains Sandeep S. , Gottlich Caleb , Herzenberg John E. , McClure Philip K.
Published: February 2025

Background:

There has been historical concern that the use of intramedullary nails could present undue risk of osteonecrosis of the femoral head due to compromise of the femoral blood supply. Intramedullary lengthening nails are rapidly becoming commonplace in lengthening procedures. As such, the primary objective of this study was to analyze the rates of osteonecrosis following femoral lengthening. The secondary objective was to characterize general trends in femoral lengthening.

Methods:

This retrospective cohort study evaluated patients who had undergone femoral lengthening at a single institution from 2012 to 2021. Retrospective chart review and radiographic evaluation of osteonecrosis were conducted. The primary end point was radiographic evidence of osteonecrosis. The secondary variables were the starting point of the femoral nail, the total amount of lengthening, and the time to consolidation.

Results:

Two hundred and forty-seven patients were included in the analysis, including 111 males and 136 females, with a mean age of 17 years. No patient had radiographic evidence of osteonecrosis (0%) or coxa valga (0%). The average amount of lengthening was 4.88 cm (range, 1.5 to 8.5 cm). No patient had any extensive complications, such as alterations in the proximal femoral anatomy.

Conclusions:

This largest study to date investigating complications following femoral lengthening using intramedullary lengthening nails revealed that femoral lengthening is a well-tolerated procedure, and osteonecrosis is an infrequent complication.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PROMOTING INCLUSIVE AND SUSTAINABLE GROWTH WITH SHARIA ECONOMY AMID THE AGE OF DIGITALIZATION AND GLOBAL UNCERTAINTIES
Authors: Warjiyo Perry
Published: February 2025

Not yet
AI-SSIM: Human-Centric Image Assessment through Pseudo-Reference Generation and Logical Consistency Analysis in AI-Generated Visuals
Authors: Danish Muhammad Umair , Aziz Memoona , Grolinger Katarina , Rehman Umair
Published: February 2025

We present AI-SSIM, a computational image metric for assessing the quality and logical consistency of AI-generated and real-world images. Traditional metrics like structural similarity index measure (SSIM) and multi-scale structural similarity index measure (MS-SSIM) require a ground-truth image, which is often unavailable in AI-generated imagery, and overlook key factors such as logical coherence and content usability. AI-SSIM addresses these gaps by employing advanced pre-trained models to generate a pseudo-reference image, convolution and attention layers to evaluate image quality, and adaptive pooling to minimize distortion during resizing pseudo-reference images. We also designed and statistically validated a multi-item questionnaire for assessing image quality. AI-SSIM was benchmarked against human scales and compared to both full-reference and no-reference metrics, where it demonstrated superior accuracy. The proposed metric has broad applicability, as it can compute scores in both scenarios where ground-truth images are either available or absent.
Mass-spectrometry-based proteomics enables rapid and accurate diagnosis of Lyme neuroborreliosis in adults
Authors: Albrechtsen Nicolai Wewer , Nielsen Annelaura , Fjordside Lasse , Drici Lylia , Ottenheijm Maud , Rasmussen Christine , Henningsson Anna , Harritshøj Lene H. , Mann Matthias , Lebech Anne-Mette
Published: February 2025

Lyme neuroborreliosis (LNB), a severe nervous system infection caused by tick-borne spirochetes of the Borrelia burgdorferi sensu lato complex, represents one of the most frequent bacterial infections of the nervous system in Europe. Early diagnosis remains challenging due to limited sensitivity of current methods and requires invasive lumbar punctures, underscoring the need for improved, less invasive diagnostic tools.
Here, we applied mass spectrometry-based proteomics to analyse 308 cerebrospinal fluid (CSF) samples and 207 plasma samples from patients with LNB, viral meningitis, controls and other manifestations of Lyme borreliosis. Diagnostic panels of regulated proteins were identified and evaluated through machine learning-assisted proteome analyses.
In CSF, the classifier distinguished LNB from viral meningitis and controls with AUCs of 0.92 and 0.90, respectively. In plasma, LNB was distinguished from controls with an AUC of 0.80.
Our findings highlight the diagnostic potential of machine learning-assisted proteomics for LNB in CSF and plasma.
Effects of genotype × environment interactions on the morphological and genetic aspects of the seed characteristics of faba beans
Authors: Mahmoud Salwa M. , Amro Ahmed , Elfarash Ameer , Börner Andreas , Sallam Ahmed
Published: February 2025

Faba bean (Vicia faba L.) is one of the oldest crops in the world. It is the third most important feed grain legume globally, after wheat and barley (Singh et al. 2013). It is an autogamous plant with 20% to 80% partial outcrossing. The objective of most crop improvement programs in faba beans is to improve yield, but yield is a complex trait that is correlated with many other traits; therefore, in this study, we focused on important traits related to faba bean improvement to increase yield, which is associated with seed characteristics. We used 110 genotypes in this study to investigate SNPs related to seed characteristics. We detected high genetic variation among all the traits. There was a strong positive correlation between the seed characteristics at the two locations. The genotype ×location (G×L) interactions were highly significant. FB-231 and FB-227 performed very well in both countries based on the SI values, whereas FB-193 and FB-185 had the lowest SI values in both countries. All genotypes were genotyped via single primer enrichment technology (SPET). As a result, we identified 33,165 SNP markers. ChrVF1L1 had the highest number of SNP markers. The total number of significant SNPs detected in Germany (162) and Egypt (31) was based on the suggestive p-value. A set of 11 SNPs was associated with more than one seed trait in Germany, whereas only one SNP was associated with two traits in Egypt.
The Impact Of Dual Trigger Stimulation Upon Reproductive Outcomes In Woman Of Advanced Maternal Age – A Large Retrospective Study
Authors: Chatziioannou Stylianos Sergios , Nikolaos Christoforidis , Chatziparasidou Alexia , Papatheodorou Achilleas , Kolias Pavlos , Drakopoulos Panagiotis
Published: February 2025

Background
Poor ovarian response (POR) in women aged 40 and above presents significant challenges in in vitro fertilization (IVF). This study evaluated whether dual trigger strategy, involving a combination of gonadotropin-releasing hormone (GnRH) agonists and human chorionic gonadotropin (hCG), improves IVF outcomes compared to human chorionic gonadotropin (hCG) alone in women of advanced maternal age.
Methods
A retrospective cohort study was conducted, analysing 2,199 IVF cycles from 1,451 women between January 2018 and June 2022. Among these cycles, 327 cycles utilized a dual trigger strategy while 1,124 had an hCG trigger. Key outcomes assessed included the number of metaphase II (MII) oocytes, fertilization rates, fresh embryo transfers on days 5/6, and pregnancy outcomes. Multivariate regression was employed to adjust for variables such as age, BMI, gonadotropin dosage, stimulation duration, and anti-Müllerian hormone levels.
Results
The dual trigger group showed significantly higher rates of embryo transfer on days 5/6 (34.1% vs. 16.5%, p < 0.001). While there were no significant differences in the number of MII oocytes or fertilization rates (p = 0.16), adjusted analysis indicated a modest increase in MII oocytes (RR = 1.1, 95% CI 1.00–1.21). Positive hCG rates were lower in the dual trigger group (18.5% vs. 24.7%, p = 0.007), and cumulative live birth rates were not significantly different (8.9% vs. 13.2%, p = 0.009).
Conclusions
Dual trigger protocols may enhance certain ovarian response parameters but do not significantly improve pregnancy or live birth rates in older women with diminished ovarian reserve. Future studies are necessary to optimize and personalize treatment strategies for this challenging patient population.
Trial Registration:
Approved by the local ethical committee (Approval 17/07/2024).
Understanding Psychological Help-Seeking in Portuguese University Students: Influences of Personality Traits, Gender, Academic and Socioeconomic Factors
Authors: Koppensteiner Laura , Silva Vânia , Ribeiro Eugénia
Published: February 2025

University students are at risk for the development of psychological problems, and their attitudes/intentions toward seeking help have been studied concerning personality traits and socio-demographics. This study utilized a convergent parallel mixed methods design, with 400 Portuguese students participating. Quantitatively, it assessed how personality traits, gender, and socioeconomic status influence attitudes, and it also considered the year of study, the scientific area, and students' intentions. The five personality traits (NEO-FFI) and attitudes (IASMHS) were analyzed. Results indicated that Openness, Conscientiousness, and Agreeableness correlated with more positive attitudes, and students who identify as women tended to have better attitudes than men. Social Science students expressed a greater intention to seek help. Qualitatively, the content analysis results showed that some students more frequently reported reasons, like understanding the need for seeking psychological help and favorable attitudes for seeking help, as facilitators. Regarding barriers, the students diverge into various factors, with intrapersonal dilemmas, stigma, and negative attitudes as the most frequently reported.
Flash Flood Hazard Mapping Using Analytical Hierarchy Process (AHP) and GIS Application: In the Barzan Area of Iraqi Kurdistan Region
Authors: Younus Mustafa Basil , Mohammed Dler Faisal  , DE WILDE Roeland  , Ali R. Ahmed  , Mohamed Moafak Arbili
Published: February 2025

Addressing the combined hazards of flooding and water scarcity in the same region requires a large-scale, evidence-based approach to disaster risk reduction. This investigation presents the evaluation of flood hazard area on a large scale for flood-prone Barzan region as a multi-criteria index, located 80 km northeast of Erbil City- Iraqi Kurdistan Region. The Flood Hazard Index (FHI) is delimited, and GIS spatial analysis is utilized to predict its value. The methodology, integrates information from ten parameters: Topographic of Wetness Index (TWI), Elevation (E), Slope (S), Precipitation (P), Land Use Land Cover (LULC), Normalized Difference Vegetation Index (NDVI), Distance from River (D1), Distance from Road (D2), Density of Drainage (D3), with type of Soil (S). The importance of each characterizes in flood amount and severity is reflected through weight values calculated utilizing the Analyzing Hierarchy Process (AHP). Flood hazard mapping is generated by superimposing information from the parameters based on their weight values. The generated flood hazard map for the area under study, classifying flood vulnerability into five categories: very low, low, moderate, high, and very high. The generated flood hazard map for the study area indicates that regions with very high and high flood susceptibility are predominantly located in the central, southeastern, and southwestern parts, with a smaller area in the northwest. The distribution of the area across different flood susceptibility levels is as follows: 14% falls into the very high category, 24% into the high category, 23% into the moderate category, 25% into the low category, and 14% into the very low category. Areas with very high flood vulnerability are primarily situated near rivers, particularly the Greater Zab and Rezan Rivers. The method's accuracy is validated through sensitivity analysis, exploring various weight values and alternative scenarios. The sensitivity analysis leads to a revised index FHIS and flood mapping, reaffirming the methodology's robustness. Comparison with historical flood actions confirms the validity of the proposed approach. The methodology therefore suggests itself as a basis for large-scale predictive flood hazard mapping. The parameters of this approach also suggest it as a potential basis for planning Nature-based Solutions (NABs) on a large geographic scale.
Kantova kritika čistog moralnog interesa
Authors: Mijatović Franjo
Published: February 2025

Autor u radu polazi od temeljnih odrednica interesa uma i nagnuća u kontekstu čovjekova odredbenog razloga djelovanja s posebnim osvrtom na pitanje čistog moralnog interesa. Temeljna je, pritom, pretpostavka shvaćanje da osjetilnost određuje ono što je ugodno i obećava osjetilnu ugodu, a um ističe ono što je dobro. Budući da svako određenje volje može nastupiti samo na jedan od ova dva načina jasno je kako svako htijenje ima interes kao osnovu. U okviru tih razmatranja rad ukazuje na probleme koji su vezani uz poteškoće razjašnjenja čistog moralnog interesa da adekvatno izrazi obvezatnost kategoričkog imperativa s obzirom na štovanje moralnog zakona. U zaključku se naglašava da se potencijalni moralni sukob između interesa nagnuća i interesa uma odnosi jedino na subjekta koji odabire osjetilno pokretalo kao moguće određenje svojega djelovanja, a ne moralni zakon kao takav.
Kantova (umna) konceptualizacija stvarnih prava i poredba u privatnopravnoj teoriji i građanskopravnoj doktrini
Authors: Nedić Tomislav
Published: February 2025

Kantovo se (umno) poimanje posjeda i stvarnih prava konceptualno i idejno postavlja u poredbeni moment u odnosu na privatnopravnu teoriju, građanskopravnu doktrinu i pozitivno zakonodavstvo. Stvarno pravo u objektivnom smislu kao »skup svih zakona koji se tiču stvarnog«, izvanjskog »mojega i tvojega« provedivo je isključivo u građanskom stanju u kojemu dolazi do konačnog stjecanja stvarnih prava čija se apriornost ogleda u posjedu. Po Kantovu uvidu, vlast nad stvari kod posjeda jest noumenon, umna povezanost osobe i stvari, dok je phaenomenon, osjetilna (fizička) povezanost stvari i osobe, samo njegova zbiljska refleksija, pri čemu takva obradba posjeda može poslužiti kao bitno objašnjenje tzv. »spiritualiziranog posjeda«, koji je, kao pripadajući genus proximum s inteligibilnim posjedom, spominjan i u građanskopravnoj doktrini. Svakom zasnivanju stvarnih prava prethodi izvoran zajednički posjed, zajednički svim ljudima kao praktički umni pojam koji u svojoj vlastitosti sadrži princip da ljudi mogu po »pravnim zakonima« rabiti određeno mjesto na Zemlji. Stvarna prava i njihovo stjecanje proizlaze iz uma jer se ona temelje na inteligibilnom posjedovanju, odnosno vlasti i inteligibilnoj svezi osobe i stvari, u kojemu osoba kao imatelj stvari svojom voljom obvezuje druge u pogledu uporabe stvari. Navedena volja mora biti u skladu s aksiomom izvanjske slobode, postulatom moći i sjedinjene volje svih. Prema permisivnom smo zakonu ovlašteni prisvajati vanjske objekte po vlastitom izboru u onoj mjeri u kojoj naše korištenje tih objekata ne krši slobodu druge osobe. U suprotnom, lišeni smo vlastite slobode te se svako ograničavanje (privatnog) vlasništva protivi našoj pojedinačnoj i sjedinjenoj volji svih u priznavanju stvarnih prava.
Extending the planar theory of anyons to quantum wire networks
Authors: Maciazek Tomasz , Conlon Aaron , Vercleyen Gert , Slingerland Johannes K.
Published: February 2025

The braiding of the worldlines of particles restricted to move on a network (graph) is governed by the graph braid group, which can be strikingly different from the standard braid group known from two-dimensional physics. It has been recently shown that imposing the compatibility of graph braiding with anyon fusion for anyons exchanging at a single wire junction leads to new types of anyon models with the braiding exchange operators stemming from solutions of certain generalised hexagon equations. In this work, we establish these graph-braided anyon fusion models for general wire networks. We show that the character of braiding strongly depends on the graph-theoretic connectivity of the given network. In particular, we prove that triconnected networks yield the same braiding exchange operators as the planar anyon models. In contrast, modular biconnected networks support independent braiding exchange operators in different modules. Consequently, such modular networks may lead to more efficient topological quantum computer circuits. Finally, we conjecture that the graph-braided anyon fusion models will possess the (generalised) coherence property where certain polygon equations determine the braiding exchange operators for an arbitrary number of anyons. We also extensively study solutions to these polygon equations for chosen low-rank multiplicity-free fusion rings, including the Ising theory, quantum double of \mathbb{Z}_{2}ℤ2, and Tambara-Yamagami models. We find numerous solutions that do not appear in the planar theory of anyons.
The impact of social responsibility on the competitive advantage of small and medium-sized enterprises in Hanoi, Vietnam
Authors: Tuan Tran The , Van Vien Bui , Thi Tho Do
Published: February 2025

Small and medium-sized enterprises account for more than 98.2% of total enterprises in Hanoi and contribute significantly to the city’s employment, innovation, and GDP. This study aims to analyze and evaluate the influence of corporate social responsibility and green marketing on the competitive advantage of small and medium-sized enterprises in Hanoi, Vietnam. With 292 valid survey responses, data analysis was conducted through PLS-SEM. The study results show that corporate social responsibility and green marketing are critical to the competitiveness of small and medium-sized firms in Hanoi. Corporate social responsibility positively influences green marketing (β = 0.812, p < 0.01) and corporate reputation (β = 0.458, p < 0.01). Similarly, green marketing strongly impacts corporate reputation (β = 0.440, p < 0.01), while corporate reputation contributes substantially to competitive advantage (β = 0.794, p < 0.01). Indirect effects were also observed. Accordingly, corporate social responsibility and green marketing enhance competitive advantage through corporate reputation, with indirect path coefficients of 0.364 and 0.350, respectively. Additionally, corporate social responsibility indirectly affects corporate reputation via green marketing (β = 0.358, p < 0.01). The findings show that integrating corporate social responsibility and green marketing strategies improves enterprises’ reputation, which in turn improves competitive advantages.
Búcsú Demény Páltól (1932-2024)
Authors: Spéder Zsolt
Published: February 2025

Demény Pál (1932-2024)
Hydrological and physicochemical parameters associated with SARS-CoV-2 and pepper mild mottle virus wastewater concentrations for a large-combined sewer system
Authors: Nguyen Thanh Luan , Hachad Mounia , McQuaid Natasha , Krylova Kateryna , Thanh Loan Nguyen Ha , Visentin Flavia , Burnet Jean-Baptiste , Quete Fernando Sanchez , Maere Thomas , Tsitouras Alexandra , Vanrolleghem Peter , Frigon Dominic , Loeb Stephanie , Dorner Sarah , Goitom Eyerusalem
Published: February 2025

During COVID-19, surveillance of SARS-CoV-2 in wastewater has been a promising tool for tracking viral infection at the community level. However, in addition to the shedding rates within the community, SARS-CoV-2 concentrations in raw wastewater are influenced by several environmental factors. This study investigated the effects of wastewater characteristics on the viral quantification of SARS-CoV-2 and pepper mild mottle virus (PMMoV) for a large wastewater system with combined sewers. Principal component analysis illustrated that water temperature negatively correlates with SARS-CoV-2 and PMMoV in wastewater, but flow rate and EC are highly correlated with SARS-CoV-2 in spring and winter. The normalization using EC enhanced the correlation with clinical data compared to normalization using pH, flow rate, and raw SARS-CoV-2. The normalization using PMMoV reduced the correlation with clinical data. Multiple linear and random forest (RF) applied to predict the concentrations of SARS-CoV-2 in wastewater, given the confirmed cases and physicochemical parameters. RF regression was the best model to predict SARS-CoV-2 in wastewater (R2=0.8), with the most important variables being the confirmed cases followed by water temperature. RF model is a potent predictor of the presence of SARS-CoV-2 in wastewater. This enhances the degree of reliability between community outbreaks and SARS-CoV-2 monitoring.
The European Union and the Violation of the Right to Self-determination. The Cases of Western Sahara and the Occupied Palestinian Territory
Authors: Arribas Gloria Fernández
Published: February 2025

Self-determination constitutes today one of the basic principles of international law. It is enshrined in the United Nations Charter and is part of the list of principles proclaimed last century in General Assembly Resolution 2625 (XXV), without a vote. The Resolution consecrated what were believed to be the essential principles to guarantee peace among states. It was adopted at specific historical time, when new states had access to the international community. These states were seeking to find their place in a world divided by an east-west confrontation which would mark international relations in the years to come.
Comments on the judgment of the International Court of Justice of 31 January 2024, Case No. 166. Application of the International Convention for the Suppression of the Financing of Terrorism and the International Convention on the Elimination of All For
Authors: Kowalczewska Kaja , Pauli Barbara
Published: February 2025

This commentary explores key aspects of the ICJ’s January 2024 judgment in Case No. 166, examining Ukraine’s claims against Russia under the ICSFT and CERD. The authors analyze five pivotal issues affecting the interpretation of international law and offering strategic insights for states considering similar legal approaches. The ICJ’s ruling on the ‘clean hands’ doctrine, dismissing it as a defense in interstate disputes, marks an important precedent, as does its interpretation of ‘funds’ under the ICSFT, limited to financial assets and excluding weapons—a decision that could influence the effectiveness of anti-terrorism financing efforts. The judgment also highlights the challenges in evidence gathering for states without territorial control. Importantly, the judgment distinguishes between compliance with provisional measures and substantive treaty violations, though it underscores the Court’s limited capacity to enforce its orders. Overall, this judgment reflects both the utility and limitations of the ICJ in conflict-related disputes, signaling a need for a more comprehensive legal framework to address state violations in war and peace.
Atividade antifúngica de óleos vegetais no controle de podridão-por-fusarium em melão e fusariose em abacaxi
Authors:   , Sousa Aline Ellen Duarte de
Published: February 2025

A utilização de óleos essenciais de plantas medicinais tem mostrado resultados
promissores no controle de patógenos de plantas. Entretanto, sabe-se que grande
parte da flora brasileira ainda não foi estudada, sendo de grande importância a
descoberta de novos compostos químicos, a partir de plantas, capazes de controlar
o desenvolvimento de fitopatógenos. O presente trabalho objetivou avaliar in vitro
e in vivo, o efeito dos óleos essenciais de alecrim-pimenta (Lippia sidoides Cham.),
alfavaca-cravo (Ocimum gratissimum L.), Ocimum sp., manjerição (Ocimum
micranthum), elixir paregórico (Ocimum selloi), laranja (Citrus sinensis), pimenta
de macaco (Piper aducum) e capim-santo (Cymbopogon citratus Stapf.), como
forma de controle de doenças causadas pelos fungos Fusarium pallidoroseum e
Fusarium subglutinans, em frutos de melão e abacaxi, respectivamente. No teste in
vitro, os óleos foram adicionados ao meio BDA nas concentrações de 0, 500, 1500
e 3000 μL L-1. Avaliou-se o crescimento micelial dos patógenos e germinação de
esporos. Nos testes in vivo, os frutos foram inoculados usando suspensão de
esporos e discos de micélio. Após 24 horas os frutos de melão foram submersos
nas soluções dos tratamentos por dez segundos. Para o abacaxi, os tratamentos
foram aplicados antes e após a inoculação, como tratamento preventivo e curativo.
Os resultados mostram que no teste in vitro os óleos de capim-limão, alecrimpimenta,
alfavaca-cravo e manjericão apresentaram potencial inibidor sobre o
desenvolvimento micelial e germinação de esporos de Fusarium pallidoroseum e
F. subglutinans. No teste in vivo todos os óleos essenciais testados causaram
queimaduras e depressões nos frutos de melão. Em infrutescências de abacaxi,
como tratamento curativo, houve controle de 100% da incidência de F.
subglutinans com os óleos de alecrim-pimenta e alfavaca-cravo em todas as
concentrações. Já como tratamento preventivo, os óleos de alecrim-pimenta e
manjericão, controlou controlaram em 100% a incidência de F. subglutinans a
partir da concentração de 1500 μL L-1.
Recent Advancement in Drug Targeting Therapies in the Treatment of Pancreatic Cancer
Authors: Harwansh Ranjit K , Hamid Junainah Abd , Wal Pranay , Deshmukh Rohitas , Patra Pratap Kumar , Gasmi Amin
Published: February 2025

Objective of the Study:

This review aims to critically analyze the scope for targeting drugs towards
the treatment of improving outcomes in PDAC, focusing on DNA repair inhibitors, antiangiogenic therapy, inhibitors
of the KRAS pathway, anti-stromal, and nanoparticle-based therapy.

Materials and Methods:

A critical review of preclinical and clinical studies was conducted to summarize the
therapeutic interventions that target specific mutations in PDAC, components of the tumor microenvironment,
and drug delivery systems, especially nanotechnology, to enhance targeting and efficacy.

Results:

Inhibitors and nanotechnology-based targeted therapies have reported promise in preclinical models:
drug delivery is enhanced with the loss of PDAC resistance mechanisms. Formulations and combinations targeting
KRAS as well as other pathways point toward improved drug delivery over 'orthodox' treatment approaches.

Conclusion:

This review concludes that although improvement in therapies for PDAC has incrementally been
proven in recent literature, however, more research is expected to enhance these approaches so that they can
be applied appropriately at the clinical stage. In future studies, it is expected to optimize treatment combinations,
address mechanisms of resistance, and improve the delivery of drugs.