bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Psychological Comorbidity on the Prognosis of Irritable Bowel Syndrome
Authors: Goodoory Vivek C. , Mikocka-Walus Antonina , Yiannakou Yan , Houghton Lesley A. , Black Christopher J. , Ford Alexander C.
Published: April 2021

INTRODUCTION:

Psychological comorbidities are associated with irritable bowel syndrome (IBS), but little is known about their cumulative effect on its prognosis. We examined this issue in a longitudinal 12-month follow-up study.

METHODS:

We collected complete demographic, symptom, and psychological comorbidity data (anxiety, depression, somatic symptom disorder, perceived stress, and gastrointestinal symptom-specific anxiety) at baseline from 807 adults who met Rome IV criteria for IBS. At 12 months, we collected data regarding IBS symptom severity and impact, consultation behavior, and treatments commenced from 452 individuals successfully followed up. We examined the cumulative effects of psychological comorbidities at baseline on subsequent IBS disease behavior.

Results:

At baseline, among the 807 participants, 177 (21.9%) had 1, 139 (17.2%) 2, 103 (12.8%) 3, 89 (11.0%) 4, and 54 (6.7%) 5 psychological comorbidities. IBS symptom severity at baseline increased significantly with the number of psychological comorbidities (72.2% of those with 5 psychological comorbidities reported severe symptoms, vs 29.1% of those with none, P < 0.001). Among 452 (56.0%) participants followed up at 12 months, those with a higher number of psychological comorbidities at baseline were significantly more likely to have seen a gastroenterologist (33.3% of those with 5 psychological comorbidities, vs 21.4% of those with none, P = 0.001), cycle through more treatments (P < 0.0001), to report more severe IBS symptoms (66.7% with 5, vs 24.4% with none, P < 0.001) and continuous abdominal pain (22.1% with none, vs 61.9% with 5, P < 0.001), and to report that symptoms impacted on daily activities ≥50% of the time (90.5% with 5, vs 41.2% with none, P < 0.001).

DISCUSSION:

The prognosis of individuals with Rome IV–defined IBS worsens according to incremental increases in psychological comorbidity. This has important clinical and research implications.
Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B
Authors: Khalili Mandana , Kleiner David E. , King Wendy C. , Sterling Richard K. , Ghany Marc G. , Chung Raymond T. , Bhan Atul K. , Rosenthal Philip , Lisker-Melman Mauricio , Ramachandran Rageshree , Lok Anna S. ,   ; and the Hepatitis B Research Network (HBRN)
Published: April 2021

INTRODUCTION:

Fatty liver disease (FLD) influences liver disease progression and liver cancer risk. We investigated the impact of FLD on liver disease severity in a large North American cohort with chronic hepatitis B virus (HBV).

METHODS:

Liver biopsies from 420 hepatitis B surface antigen-positive adults enrolled in the Hepatitis B Research Network and who were not on HBV therapy in the previous month were evaluated for inflammation and fibrosis. Steatohepatitis was based on steatosis, hepatocyte ballooning ± Mallory-Denk bodies, and perisinusoidal fibrosis. Models evaluated factors associated with steatohepatitis, and the associations of steatohepatitis with fibrosis, and longitudinal alanine aminotransferase, aspartate aminotransferase, and Fibrosis-4.

RESULTS:

The median age was 42 years, 62.5% were male, and 79.5% were Asian. One hundred thirty-two (31.4%) patients had FLD (77 [18.3%] steatosis only, 55 [13.1%] steatohepatitis). Older age, overweight/obesity, and diabetes were associated with steatohepatitis. Steatohepatitis (vs no FLD) was associated with 1.68 times higher risk of advanced fibrosis at baseline (95% confidence interval, 1.12–2.51), and there was an indication of higher incident cirrhosis rate during follow-up. Steatohepatitis vs no FLD was also independently associated with, on average, 1.39 times higher alanine aminotransferase (P < 0.01) and 1.25 times higher Fibrosis-4 (P = 0.04) across 4 years.

DISCUSSION:

Coexisting steatosis occurred in nearly a third of adults (13% had steatohepatitis) with chronic HBV in this North American cohort who underwent liver biopsies. Steatohepatitis was associated with advanced fibrosis and higher biochemical measures of hepatic inflammation over time. Therefore, in addition to viral suppression, screening for and managing metabolic abnormalities is important to prevent disease progression in HBV.
Progress in Corticosteroid Use in the Era of Biologics With Room for Improvement
Authors: Abdalla Maisa I. , Levesque Barrett G.
Published: April 2021

With the early success of their trials for the treatment of ulcerative colitis, corticosteroids gained popularity as a treatment for inflammatory bowel disease (IBD). However, when used chronically, corticosteroids are not effective in maintaining remission and associated with toxic effects. Steroid-free remission has become a major treatment goal. Prolonged corticosteroid use is currently a sign of suboptimal quality of care. Trends over the past 2 decades, spanning the emergence of biologic therapies for IBD, are explored here in the University of Manitoba IBD Epidemiologic Database.
O método da igualdade: Jacotot e a experiência do ensino universal no contexto da Revolução Francesa
Authors: Cruz Crislaine Santana , Bretas Silvana Aparecida
Published: April 2021

Esse texto tem como propósito apresentar a vida e obra do fundador do Ensino Universal, Joseph Jacotot (1770-1840); bem como analisar os aspectos históricos e filosóficos de seu método educativo, a fim de apresentar uma compreensão preliminar de suas ideias acerca da educação nos anos iniciais do século XIX, em que se fortalecia o pensamento pedagógico que deu origem a educação moderna. O método do Ensino Universal, também conhecido como método da emancipação intelectual, se baseia nos princípios de que: 1) Todos os homens têm inteligência igual; 2) Todo homem recebeu de Deus a faculdade de ser capaz de se instruir; 3) Podemos ensinar o que não sabemos; 4) Tudo está em tudo; e, se oporá ao pensamento educativo da época por acreditar na opinião de que todas as inteligências são iguais e de que não se atingirá a igualdade entre os homens, pretendida pela Revolução Francesa, com a criação de instituições de ensino e com a formação de mestres explicadores, mas somente dando a cada homem o poder de reconhecer sua capacidade intelectual. Esta pesquisa se baseia no referencial teórico do materialismo histórico-dialético.
Programas para la educación rural en el norte de la provincia de Entre Ríos (Argentina, 1978-2018)
Authors: Petitti Eva Mara , Schmuck María Emilia
Published: April 2021

El artículo se propone examinar los cambios y las permanencias así como las coexistencias y superposiciones entre los principales programas orientados a la educación rural que se implementaron en la provincia argentina de Entre Ríos y especialmente en el norte, a lo largo de cuatro décadas durante las que se sucedieron diferentes gobiernos, tanto dictatoriales como democráticos (1978-2018). Para ello consultamos normativas nacionales y provinciales, documentos y registros elaborados en el marco de los diferentes programas estudiados, así como también recuperaremos entrevistas y parte del trabajo de campo etnográfico de una investigación previa. A lo largo del trabajo distinguimos cinco programas que en mayor o menor medida, según los casos, han estado superpuestos tanto en lo que respecta a los momentos de inicio y cierre, como a los actores que participaron en los mismos. Mostramos que sus objetivos fundamentales y su organización han sido construidos de manera articulada.
A constituição técnica e teórica do Repositório Digital Tatu
Authors: Gervasio Simôni Costa Monteiro , Bica Alessandro Carvalho , Rodrigues Tobias de Medeiros
Published: April 2021

Este artigo tem como objetivo problematizar uma iniciativa desenvolvida no âmbito do projeto de pesquisa “Educação, História e Políticas na região de abrangência da Universidade Federal do Pampa” e refere-se, especialmente, ao processo de criação e desenvolvimento de um repositório digital. A proposta de criação de um espaço virtual capaz de armazenar e compartilhar acervos apoia-se na necessidade de preservação das fontes e possibilidade de acesso para diversos pesquisadores interessados em explorar as possibilidades contidas nos documentos, revistas, periódicos educacionais e outros materiais pertencentes ao acervo. Assim, este artigo trata do percurso de criação deste repositório digital, passando pelo processo de tratamento das fontes, sua digitalização e organização do repositório que pode ser acessado por meio do endereço eletrônico http://sistemas.bage.unipampa.edu.br/tatu/, destacando o potencial no intercâmbio entre áreas como a tecnologia da informação, educação e história, para a criação de soluções versáteis.
Effect of Employee Performance Factors on Corporate Performance: Evidance in Information Technology Firm
Authors: Suciati Lina
Published: April 2021

The MNC (Multinational) company based in California is a computer storage and data management (storage) company. PT. NetApp is very concerned about the welfare of its employees. All NetApp achievements are inseparable from good management of its human resources, in this context the performance of its employees. Although NetApp is one of the best companies at work, the percentage of employee turnover has increased from year to year. This type of research is quantitative research. Sugiyono (2007) Quantitative data is data in the form of numbers, or qualitative data that is called up (scoring). This study is intended to determine the relationship between the seven variables, namely Recruitment of Independent Variables (X1) and Career Path (X2), namely Corporate Performance Dependent variable (Y) and Employee Performance (Z) as a variable intervening. After a statistical test, the results are obtained: first the recruitment variable has a significant effect on corporate performance variables. This means that recruitment is the initial stage of the employee to enter into a company. not significant to corporate performance variables
The Efffect of Profitability, Fundings, and Financing for Corporate Social Responsibility Disclosure in Islamic Banking
Authors: Sari Risti Lia
Published: April 2021

The purpose of this study is to analyze the effect of profitability, fundings, and financing on the disclosure of Corporate Social Responsibility in Islamic Banks in Indonesia. The sample used was 11 Islamic banks in Indonesia which were listed on the Indonesia Stock Exchange and consistently published financial statements and corporate social responsibility reports for the period 2012-2018. The analysis of this study uses the multiple regression method (multiple regression). The results of the study explained that Profitability, Fundings and Financing together have a significant positive effect on CSR (Corporate Social Responsibility). Constraints that are still commonly found in the implementation of CSR are cost issues, competent human resources, distribution of activities and determination of targets, forms of activities, licensing and regulatory issues, lack of partnerships, socialization of activities, understanding of implementation and evaluation in the field, and many persons who carry out illegal levies on the ground.
Effect of Customer Value and Satisfaction on Customer Loyalty: Evidence on Indonesian Islamic Bank
Authors: Indana Rifaatul
Published: April 2021

Given the importance of perceived value and high satisfaction for companies in creating loyalty to achieve their goals and to empirically prove testing, the researchers formulated the problem in research specifically: (1) Does perceived value have an influence on customer loyalty, (2) Does satisfaction affect customer loyalty?. This study uses a Structural Equation Modeling (SEM) approach which is carried out through AMOS software. This research was conducted by utilizing community surveys with online questionnaire. The Sample of this research is 150 respondents, majority of respondents came from the provinces of Central Java and the Special Region of Yogyakarta. Based on the results of the analysis show: customer value has a positive effect on customer satisfaction (CR = 2.492, P = 0.019, H1 supported), customer value has a positive effect on customer loyalty (CR = 2.53, P = 0.026, H2 supported), customer satisfaction has a positive effect on customer loyalty (C.R. = 3.521, P = 0.000, H3 supported). Satisfaction are in a position to create a positive response to the creation of services for consumers, furthermore perceived value plays an important role in representing various client needs and company satisfaction, in the right preferences.
The influence of medical and social risk factors on the development of hypertension in the adult population at the regional level
Authors: Lashkul Z. V. , Lashkul D. A.
Published: April 2021

The aim of the study was to investigate the impact of medical and social risk factors (RF) on the development of arterial hypertension (AH) in the adult population at the regional level (Zaporizhzhia, Ukraine).
Materials and methods. The study, after obtaining an informed consent, involved 2000 patients, residents of Zaporizhzhia region, including 1000 patients (522 men and 478 women, mean age 51.60 ± 0.85 years) with AH and 1000 patients (478 men and 522 women, mean age 49.80 ± 0.94 years) without AH. The relationship between hypertension and the action of already known RF, the reliable connection of which has been proven by many studies, including burdened heredity, overweight, excessive alcohol consumption, smoking, physical inactivity, and some social and economic RF. In order to achieve the goal of the study, we used a set of general scientific and special interrelated and consistently applied methods: system analysis, bibliosemantic, descriptive statistics, calculating the odds ratio (OR) of the event with a 95 % confidence interval (CI); values of P to define statistical significance.
Results. According to our study, the simple logistic regression analysis of persons from the study cohort reveals a reliable relationship (P < 0.05) between AH and family history of hypertension, overweight, physical inactivity, smoking. Along with the well-known RF, the residents of the Zaporizhzhia region are exposed to other social and economic RF, in particular, poor living standards (OR 2.45; 95 % CІ 2.04–2.94; P < 0.0001), unemployment (OR 1.9; 95 % CІ 1.38–2.64; P < 0.0001), lack of healthcare facilities at the place of residence (OR 0.29; 95 % CІ 0.22–0.35; P < 0.0001), low level of education (OR 2.39; 95 % CІ 1.97–2.91; P < 0.0001).
Conclusions. It has been found that along with the traditional risk factors, the residents of the Zaporizhzhia region have other social and economic risk factors, including poor living standards, low average income, unemployment, lack of healthcare facilities at the place of residence, low level of education.
Biochemical predictors of chronic kidney disease in children recovering from acute kidney injury
Authors: Lavrenchuk O. V. , Bahdasarova I. V. , Korol L. V. , Myhal L. Ya.
Published: April 2021

The pressing question today is to find early informative markers for kidney interstitial injury in reconvalescents of acute kidney injury (AKI).
The aim of the study was to determine the informativeness of transferrin (TF), ceruloplasmin (CP) presence and activity level of lysosomal enzymes in urine as predictors of chronic kidney disease.
Materials and methods. The contents of TF, CP and N-acetyl-β-Dgluosaminindase (NAG) and β-galactosidase (ß-GAL) in the urine of 41 children after AKI were determined. All patients were divided into 2 groups depending on the disease duration – group 1 included 22 patients with 12 months’ duration, group 2 – 19 children with the disease duration of 2 years and more. The control group consisted of 28 conditionally healthy children.
Results. The levels of NAG and ß-GAL were 8 and 3 times increased, respectively, in the patients from group 1 in comparison with the control group (P < 0.001). In the group 2 children, the enzyme levels were 4 times higher than the control, and albuminuria was observed at normal GFR (P < 0.001). An inverse correlation was established between GFR indices and activity levels of NAG (r = -0.473) and ß-GAL (r = -0.333), and a direct correlation between activity indices of GAG and ß-GAL (r = 0.845). The presence and high levels of TF in 18.8 % of children in group 1 and in 21.0 % in group 2, as well as urine CP in 72.7 % of patients in group 1 and in 78.9 % in group 2, is indicative of a progressive damage to the kidney glomerular apparatus.
Conclusions. The presence and increased quantitative parameters of TF and CP in the urine of children after AKI are early signs of damage to the kidney glomerular apparatus. Four times increased levels of the enzyme activity and albuminuria at unchanged GFR indicate an interstitial kidney injury (P < 0.001). The examinations conducted are non-invasive, relatively low cost and easy to use for children of all ages.
The kariotype variability in children with Down syndrome from the Odesa region
Authors: Kulbachuk N. V. , Matviiuk S. V. , Bilokon S. V. , Sechnyak O. L.
Published: April 2021

The aim of the work is to analyze the frequency of cytogenetic variants of Down syndrome among patients in Odesa and the region, as well as to identify combined karyotype anomalies.
Materials and methods. Studies were conducted between 2013–2018 years in Odesa Specialized Medical Genetic Center. The experimental group was formed of patients with cytogenetically confirmed Down syndrome. Chromosomes were painted according to GTG method and identified according to ISCN 2013.
Results. Among patients with Down syndrome, in 93.9 % of cases complete trisomy 21 was observed, the translocation form was in 3.7 %, and the mosaic form was in 2.4 %. Similar results were revealed in the analysis of populations belonging to different ethnic and racial groups. Complete trisomy 21 was accompanied by chromosome rearrangements of other chromosomes or additional modifications of chromosome 21. Changes in the heterochromatin in chromosome 9 were more frequently observed. In total, 5.5 % of examined karyotypes were found with additional heterochromatin in both arms of chromosome 1 and in the long arm of chromosome 21. An increase in the size of satellites in chromosomes 14, 15 and more often 21, as well as the appearance of additional satellites in chromosome 2 represented 3.6 % of the total examined karyotypes. A deletion on chromosome 6 involved in translocation with chromosome 13 also was found. Translocation forms included Robertsonian translocations involving chromosomes 21 and 21, 14 and 21, as well as translocations involving chromosomes 21 and 21, 21 and 22. Patients with a mosaic form of the disease had two cell lines: with a normal karyotype 3 (15–67 % of the studied cells) and with complete trisomy 21 without additional chromosomal abnormalities (33–85 % of the studied cells).
Conclusions. Among patients with cytogenetically confirmed diagnosis of Down syndrome, the ratio of the main variants was similar to many populations studied. At the same time, additional changes in the karyotype were identified which can either be a variant of the norm or aggravate the course of the disease. This requires further studies of the disease course in such patients.
The effect of drug treatment on functional outcomes of hip and knee joint replacement in patients with rheumatoid arthritis
Authors: Herasymenko S. I. , Herasymenko А. S. , Huzhevskyi I. V. , Poluliakh M. V. , Babko A. M.
Published: April 2021

Aim – to determine the effect of drug antirheumatic therapy on the functional outcomes of hip and knee arthroplasty in patients with rheumatoid arthritis.
Materials and methods. The results of 160 operations of total hip arthroplasty and 148 operations of total arthroplasty of knee joints in patients with rheumatoid joint lesions were analyzed using mathematical methods of statistical processing. Patients were divided into 4 groups: Group I – without anti-inflammatory therapy, Group II – received hormone therapy, Group III – basic therapy and Group IV – received both the basic and hormonal therapy at the time of surgery.
Results. The obtained results indicated a moderate correlation between therapy and the joint range of motion of the lower extremities using basic therapy and combined nonsteroidal, hormonal and basic therapy, and the range of motion differed significantly in combination therapy from hormonal alone. The highest scores of the J. Joseph, E. E. Kaufman rating scale were observed in combination therapy with NSAIDs, hormonal and basic therapy; the lower scores – in hormonal and NSAIDs combination; and the lowest ones – in the combination of basic therapy with NSAIDs. The greatest increase in the knee joint range of motion was observed in the patients who received hormonal drugs or basic therapy compared to the patients who did not take any one or received both of these medicines in combination. Almost the same effect of antirheumatic therapy on the results of both hip and knee arthroplasty was determined with an upward trend in percentage of good and excellent results in males regardless of the lesion location and the most optimal ratio between satisfactory-unsatisfactory and good-excellent results in the patients under 40 years of age.
Conclusions. The studies conducted allow to consider the combined drug therapy as a factor of weak and moderate influence on the functional outcomes of hip and knee arthroplasty in the late stages of rheumatoid arthritis and suggest that antirheumatic drug therapy should not be discontinued in the perioperative period.
Study of the qualitative composition and quantitative content of some groups of BAS in dietary supplements with green tea leaf extract
Authors: Maslov O. Yu. , Kolisnyk S. V. , Hrechana O. V. , Serbin A. H.
Published: April 2021

Recently, there has been a high demand from the population for dietary supplements that have antioxidant activity. First of all, these are dietary supplements with green tea leaf extract, because green tea contains catechins in a fairly high amount. Nowadays, according to the current legislation of Ukraine the qualitative composition and quantitative content of biologically active substances in dietary supplements are not established, which to a certain extent affects the quality and safety of these products.
The aim of the study was to determine the qualitative composition and quantitative content of some groups of BAS in dietary supplements with green tea leaf extract.
Materials and methods. Three dietary supplements from different manufacturers “Green Tea Extract”, “Green Tea Extract”, “Green Tea” were chosen for the study. Qualitative analysis was performed by thin layer chromatography, for quantification spectrophotometry in the UV-region was used.
Results. The presence of catechins was found in the studied dietary supplements, caffeine was found only in trace amounts. The total content of catechins is 146.80 ± 1.36 mg, 79.00 ± 0.88 mg, 28.00 ± 0.75 mg, and in terms of green tea extract, which is stated in dietary supplements
for dietary supplements “Green Tea Extract”, “Green Tea Extract”, “Green Tea”, respectively.
Conclusions. Qualitative and quantitative analysis of some groups of BAS of three dietary supplements with green tea leaf extract was performed. It was found that dietary supplements “Green Tea Extract” and “Green Tea” meet the requirements of the US Pharmacopoeia 38 in terms of catechins. Based on the study, it can be concluded that the problem of compliance with dietary supplements is relevant today and requires the introduction of regulatory documentation for the detection and determination of biologically active substances in dietary supplements.
Endothelial dysfunction in patients with chronic obstructive pulmonary disease: some aspects of medicamental treatment (a literature review)
Authors: Lemko O. I. , Vantiukh N. V.
Published: April 2021

The aim of the study was to analyze the professional literature concerning general principles of medicamental correction for endothelial dysfunction and their peculiarities in patients with chronic obstructive pulmonary disease. 
The development of chronic obstructive pulmonary disease (COPD) is based on certain trigger factors and pathogenetic processes (chronic inflammation of low intensity, oxidative stress, endothelial dysfunction). These factors are common for a number of other pathological processes, promoting the development of systemic extrapulmonary effects and comorbid conditions. Endothelial dysfunction is of particular interest because it causes, first of all, cardiovascular system pathology. Therefore, modern treatment of COPD, in addition to the drugs approved by clinical protocols, must be supplemented by methods of endothelial dysfunction correction in the long-term management for patients beyond the exacerbation period, which at the same time have no negative effect on the disease course.  
At present, medicines of various pharmacological groups with a positive effect on the endothelial function are known. Among them are those ones that replenish the deficiency of endothelial relaxing factors or have a direct effect on endothelial receptors; stimulate endothelial nitric oxide synthase activation; prevent endothelial dysfunction caused by mediator influences; regulate the blood coagulation system; provide protection from endothelial cell membrane damage or affect various pathogenetic links of the disease (inflammatory process, immune disorders, dysbiosis, etc.), that indirectly reduces endothelial dysfunction.  
Conclusions. The key role of endothelial dysfunction in the formation of comorbid pathology in COPD, first of all lesions of cardiovascular system, determines the necessity for complex treatment of these patient groups with additional correction of endothelial dysfunction, especially in long-term management programs beyond the exacerbation period. Given the multifactorial mechanisms of endothelial dysfunction development, the treatment choice for its correction should be personalized taking into account all the disease peculiarities and the comorbid pathology spectrum.
Biocompatibility of implants in planned and urgent hernia surgery
Authors: Slonetskyi B. I. , Tutchenko M. I. , Verbytskyi I. V. , Kotsiubenko V. O.
Published: April 2021

The aim of the work – to analyze modern scientific and practical achievements in the effectiveness of implants in planned and emergency hernia surgery and to identify promising areas for further research.
The literature review presents modern views on the assessment of biocompatibility, effectiveness and appropriateness of the use of implants in planned and urgent hernia surgery. The importance of determining the main factors of ventral hernia occurrence, assessing the prognostic components of the reparative process course in the field of hernioplasty and methods of correction has been substantiated. Physicochemical characteristics of implants, which both historically and on an up-to-date level are used according to planned or urgent conditions for performing surgical intervention in patients with ventral hernias, are given. The necessity of using an integrated approach to choosing a method for correction or reconstruction of the abdominal wall, taking into account the biological and dynamic conditions of its state, is shown. The need for a selective approach to the choice of therapeutic tactics in patients, especially if hernia repair is necessary in conditions of a clean-contaminated or infected surgical wound, is emphasized.
Conclusions. In order to improve the consequences of hernioplasty, it is necessary to assess patient's reserves and risks more thoroughly and comprehensively, as well as to make absolute indications for the use of implants. An improvement in the results of urgent and planned repair of ventral hernias is to perform surgical interventions only in surgery departments constantly provided with modern world achievements.
WPROWADZENIE
Authors: Obrębska Monika , Bakiera Lucyna
Published: April 2021

WPROWADZENIE
Monitorowanie wypowiedzi a realizacja intencji w procesie mówienia
Authors: Bręński Szymon
Published: April 2021

Speech production is complex and high organized process. It starts with some intention, which in following steps is transformed into articulated and audible form. Sometimes speech production fails and results in a speech error (or a slip of the tongue), which changes meaning of the utterance and disturbs the process of the realization of intention. However, speech monitoring helps to detect and repair the error with respect to the original intention of the speaker. Thus the speaking appears as a way of the realization of intention and the intention plays integrational function in relation to the process of speaking. According to Frydrychowicz (1999), the process of the realization of intention can be divided into several phases, distinguished by psychophysical features of speaking. He found that voice intensity is highest when the speaker is close to fully realizing the intention. The aim of the current study is to examine this voice intensity effect in relation to speech error repairs as speaking units which re-establish the process of the realization of intention. The question is, howthese corrections of the course of speech are reflected in the voice intensity? The results obtained from errors and repairs induced in the dual task paradigm show that voice intensity rises when the speaker makes a self-repair by speaking a correct word.
Niejednoznaczność wypowiedzi humorystycznych a kompetentne komunikowanie się
Authors: Kucharski Adam
Published: April 2021

The aim of this paper was to discuss competent communication, specifically humorous statements containing ambiguity. Attention was brought to difficulties when deciding between informative and humorous manners of communication. It is not easy to differentiate between the two manners, which means we do not always adjust to the correct manner when speaking with our conversationalist. It brings special difficulties, when the communicator knowingly does not state what manner his speech should be received in. Farther, we cannot always form a phrase in a certain manner, even if the manner is known to us, which can lead to further issues in communication. Communication competency, including humour competency is not only the ability to understand and appreciate the humorous aspect in the message, but also the ability to formulate a humorous statement appropriate for the situation and to the aims raised by an individual.
Przemoc i agresja u dzieci i młodzieży. O języku agresji
Authors: Sileńska Aleksandra , Szpunar Kamila
Published: April 2021

Aggression is defined as the intentional action which causes pain and injury. The actions of an aggressive nature are designed to cause physical or mental harm to another person (Aronson, Wilson, & Akert, 1997). In contrast, violence is defined as an intentional action that goes beyond social norms and causes mental or physical pain (Pospiszyl, 1999). The article is concentrated on aggressive and violent language among children and adolescents. The term of ”language of aggression” has not been precisely defined yet. The language of aggression occurs the most when negative emotions and intentions are involved in the communication (Majchrzyk, 2002). The language of aggression is not only about using specific bad words but also about the way we speak. The article presents an overview of Polish and foreign literature concerning the issue of the language of aggression in children and adolescents. It shows why do teenagers and children use aggressive language, how is defined term of ”aggressive language” and what specialists can do to prevent such kind of problem.
Errata for "Cerebro: a data system for optimized deep learning model selection"
Authors: Nakandala Supun , Zhang Yuhao , Kumar Arun
Published: April 2021

We discovered that there was an inconsistency in the communication cost formulation for the decentralized fine-grained training method in
Table 2
of our paper [1]. We used Horovod as the archetype for decentralized fine-grained approaches, and its correct communication cost is higher than what we had reported. So, we amend the communication cost of decentralized fine-grained to

[EQUATION]
Fast algorithm for anchor graph hashing
Authors: Fujiwara Yasuhiro , Kanai Sekitoshi , Ida Yasutoshi , Kumagai Atsutoshi , Ueda Naonori
Published: April 2021

Anchor graph hashing is used in many applications such as cancer detection, web page classification, and drug discovery. It computes the hash codes from the eigenvectors of the matrix representing the similarities between data points and anchor points; anchors refer to the points representing the data distribution. In performing an approximate nearest neighbor search, the hash codes of a query data point are determined by identifying its closest anchor points. Anchor graph hashing, however, incurs high computation cost since (1) the computation cost of obtaining the eigenvectors is quadratic to the number of anchor points, and (2) the similarities of the query data point to all the anchor points must be computed. Our proposal,
Tridiagonal hashing
, increases the efficiency of anchor graph hashing because of its two advances: (1) we apply a graph clustering algorithm to compute the eigenvectors from the tridiagonal matrix obtained from the similarities between data points and anchor points, and (2) we detect anchor points closest to the query data point by using a dimensionality reduction approach. Experiments show that our approach is several orders of magnitude faster than the previous approaches. Besides, it yields high search accuracy than the original anchor graph hashing approach.
An inquiry into machine learning-based automatic configuration tuning services on real-world database management systems
Authors: Van Aken Dana , Yang Dongsheng , Brillard Sebastien , Fiorino Ari , Zhang Bohan , Bilien Christian , Pavlo Andrew
Published: April 2021

Modern database management systems (DBMS) expose dozens of configurable knobs that control their runtime behavior. Setting these knobs correctly for an application's workload can improve the performance and efficiency of the DBMS. But because of their complexity, tuning a DBMS often requires considerable effort from experienced database administrators (DBAs). Recent work on automated tuning methods using machine learning (ML) have shown to achieve better performance compared with expert DBAs. These ML-based methods, however, were evaluated on synthetic workloads with limited tuning opportunities, and thus it is unknown whether they provide the same benefit in a production environment.

To better understand ML-based tuning, we conducted a thorough evaluation of ML-based DBMS knob tuning methods on an enterprise database application. We use the OtterTune tuning service to compare three state-of-the-art ML algorithms on an Oracle installation with a real workload trace. Our results with OtterTune show that these algorithms generate knob configurations that improve performance by 45% over enterprise-grade configurations. We also identify deployment and measurement issues that were overlooked by previous research in automated DBMS tuning services.
Las redes sociales digitales como espacio para ser otro: una discusión teórica
Authors: Orozco Macias Andrés Fernando
Published: April 2021

La investigación analiza la aplicación de nuevos conceptos como campo de sentidode Marcus Gabriel (2019), simulacrode Jean Baudrillard (2010) y positivizaciónByung-Chul Han (2018ª) a las investigaciones relacionadas con la participación de los individuos en el espacio digital. La investigación pretende ampliar el abordaje teórico de estos temas más allá de análisis psicosociales pretendiendo una reflexión fenomenológica que permita indagar ¿Quién es el hombre frente a la pantalla? y ¿Cómo comprender su actuar y sus múltiples facetas en sus redes sociales digitales? Para anclar los conceptos, se hace un breve análisis tomando dos acontecimientos de usurios suplantados en las redes sociales. Finalmente, se plantea la necesidad de que el estudio de los fenómenos de redes digitales se desliguen de áreas de estudio tradicionales que corresponden a otras reflexiones sociales, permitiendo pensar estas problematicas desde nuevos conceptos que den una mirada más allá de la operatividad productiva de Internet y profundicen en el cambio antropológico que están generando a través de la positivización, lo espectacular y la modificación de la imagen y semejanza de lo que quisiera ver cada internauta de si mismo.
Fandom televisivo. Estudio de su impacto en la estrategia de comunicación en redes sociales de Netflix
Authors: Martínez-Sala Alba-María , Barrientos-Báez Almudena , Caldevilla-Domínguez David
Published: April 2021

Las nuevas formas de consumo audiovisual dan protagonismo al fandomtelevisivo por el potencial que ofrece a las organizaciones del sector, como Netflix, respecto de uno de sus públicos principales, los adolescentes. Esta investigación analiza el impacto de este fenómeno en la interacción y engagement onlinede los seguidores de Netflix en Twitter e Instagram. Para ello se realiza un análisis de contenido cuantitativo que clasifica las publicaciones en función de dos indicadores: contenido y finalidad de las publicaciones. En lo que respecta al primero, el contenido, la distribución está bastante equilibrada y las publicaciones que versan sobre series de televisión generan buenos niveles de interacción y engagement onlinerevelando la incidencia del fandomtelevisivo, sobre todo en la red social Instagram. Con relación al segundo, la finalidad, se observa una escasa presencia de las participativas pese a que generan mayores niveles de interacción y engagement online. Se concluye acerca de las ventajas del fandomtelevisivo y de una incipiente explotación del mismo que puede mejorarse dotando a las publicaciones sobre series de un carácter participativo, pero, también, se constata un correcto enfoque de la estrategia de comunicación de la marca al contemplar distintas actuaciones acordes a las características y públicos representativos de cada red social.
METHOD OF AUTOMATIC DETERMINATION OF THE HEART’SELECTRICAL AXISIN CARDIOLOGICAL DECISION SUPPORT SYSTEMS
Authors: Filatova Anna E. , Fahs Mohamad
Published: April 2021

The work is devoted to solving the scientific and practical problem of automating theheart’selectrical axis calculationto im-prove the quality of morphological analysis of biomedical signals with locally concentrated features in cardiological decision support systems, which in turn reduces the likelihood of medical errors.The work shows that existing methods forin thedetermining the electrical axis of the heart require morphological analysis of an electrocardiogram.The method is based on determining the integral signal in the frontal plane fromall limb leads, taking into account the lead angle in the hexaxial reference system.In graphic form in polar coordinates, the integral electrocardiological signal is a figure, predominantly elongated along the axis, the direction’n of which corresponds to the heart’selectrical axis.The position of the heart’selectrical axis is calculated as the angle between the axis of standard lead I and the vector, the end of which is at the center of mass of the locus of thepoints the farthestaway from the reference point.Cluster analysis is used to find the most distantpoints from the reference point.The proposed method forof calculating the heart’selectrical axis makes it possible not to carry out a preliminary morphological analysis of an electrocardiogram.To implementthe method proposed in the article, a program was written in the Matlab language, which is connected asa dynamic link library to the cardiological decision support system “TREDEX telephone”operating as part of the medical diagnostic complex “TREDEX”manu-factured by “Company TREDEX”LLC, Kharkiv.Verification of the results was carried out using a database of electrocardiograms, which were recorded using a transtelephone digital 12-channel electrocardiological complex “Telecard”, which is part of the medical diagnostic complex “TREDEX”, and deciphered by cardiologists of the communal non-profit enterprise of the Kharkiv Regional Council “Center for Emergency Medical aid and disaster medicine”.Comparison of the results of calculating the heart’selectricalaxis according toelectrocardiogramsby a doctor and automatically using the proposed method showed that in the overwhelming majority of cases the decisions made coincide.At the same time, cardiologists make mistakes, and errors are made during automaticcalculation using the proposed method.The paper explains the reasons for these errors.
DYNAMIC PERFORMANCES OF THE SHUNT ACTIVE POWER FILTER CONTROL SYSTEM
Authors: Peresada Sergiy M. , Kovbasa Sergiy M. , Zaichenko Yuriy M.
Published: April 2021

Harmonic pollution of the electrical mains is well known and well-studied phenomena. Active power filter being a powerful tool to meet the requirements of regulatory documents regulating the electricity quality. Despite this fact, practical implementation of the active power filter is still connected with significant difficulties. In particular, existing systems typically use fast Fourier transform methods or instantaneous power theory to estimate the harmonic composition of the mains current. However, the use of fast Fourier transform requires high computing power of the control system, and the implementation of the theory of instantaneous power significantly increases the requirements for the power part of the active filter. The application of another approach -selective compensation of harmonics, makes it possible to reduce computational requirements and significantly simplify the technical implementation of the active filter and at the same time to achieve an acceptable level of distortion compensation. In this paper, the shunt active power filter control system is designed and investigated. Proposed control system consist of selective harmonics observer, feedback-linearizingcurrent controller, dc-link controller and mains voltage observer. Harmonics observer is tuned according to simplified approach,provides selective estimation of the load current harmonics and produce the compensation current reference for the current controller.Nonlinear dc-link voltage controller guarantees decoupled from current compensation process asymptotic regulation of the average dc-link voltage. Mains voltage vector adaptive observer provides magnitude, angular position and frequency estimation. Proposed control system is implemented on digital signal processor TMS320F28335 end verified experimentally. Results of experimental investigations together with results of simulations confirm effectiveness of proposed solution. Developed control system can be used for shunt active filters implementation.
Šiaurės žemaičių afrikatų ir heteromorfeminių T–S tipo junginių akustinės ir audicinės ypatybės
Authors: Kubiliūtė Regina , Girdenis Aleksas
Published: April 2021

Vladas Grinaveckis “Žemaičių tarmių istorijoje” ir kituose savo darbuose rašo, kad žemaičių afrikatos galinčios būti kilusios išjunginių t+s, d+s, t+š, d+š, t+z, d+ž, t+ž. Iki šiol tokios nuomonės buvo ir kiti dialektologai. Kiek daugiau diskutuota tiktai dėl bendrinės kalbos afrikatų ir heteromorfeminių TS tipo junginių. V. Vaitkevičiūtė ir E. Mikalauskaitė kalbamuosius junginius laikė savarankiškų garsų samplaikomis, o A. Pupkis iškėlė ir eksperimentiškai motyvavo alternatyvią hipotezę, tvirtinančią, kad vakarų aukštaičių kauniškių tarmėje ir bendrinėje kalboje afrikatos nesiskiriančios nuo TS junginių. Šį ginčą pirmosios hipotezės naudai, rodos, galutinai išsprendė M. Strimaitienė, kuri gausiais eksperimentais įrodė, kad bendrinėje kalboje TS junginiai savo trukme ryškiai skiriasi nuo afrikatų. Kadangi trukmė yra ryškiausias fizinis afrikatų ir TS junginių skiriamasis požymis, patikimiausias jų indikatorius, praktiškai neliko abejonės, kad bendrinėje kalboje afrikatos skiriasi nuo atitinkamų junginių. Šios išvados paskatino grįžti ir prie žemaičių afrikatų bei junginių: jau minėtos V. Grinaveckio knygos recenzentai, remdamiesi savistaba, netrukus pareiškia nuomonę, kad ir žemaičių afrikatos ne visai sutampa su TS junginiais. Tuo būdu susidarė probleminė situacija, kuri ir paskatino mus imtis šiame straipsnyje aprašomo tyrinėjimo: akustinės bei audicinės kalbos signalų analizės ir jos rezultatų statistinio įvertinimo metodais patikrinti, ar šiaurės žemaičių afrikatos ir heteromorfeminiai TS tipo junginiai yra tapatūs fonetiniai ir fonologiniai reiškiniai, ar skirtingi.
ASSESSMENT OF CELLULASE COMPLEX SECRETORY CAPACITY OF TRICHODERMA STRAINS AND MORPHOLOGICAL AND MOLECULAR IDENTIFICATION OF THE ISOLATE WITH THE HIGHEST ENZYMATIC SECRETION CAPACITY
Authors: Castrillo Maria Lorena , Bich Gustavo Ángel , Amerio Natalia Soledad , Rodriguez Maria Daniela , Zapata Pedro Dario , Villalba Laura Lidia
Published: April 2021

The bioconversion of lignocellulosic biomass into monomeric sugars is a key economic difficulty hindering the profitable use of plant biomass as energy. The production of cellulase is a main factor in the cellulose hydrolysis. Among the main cellulase producers are the filamentous fungi. Therefore, many efforts have been made in obtaining new microorganisms with high cellulase secretion capacity. The cellulase secretory capacity of 28 isolates of Trichoderma was qualitatively and quantitatively evaluated. The detection of cellulolytic fungi was correlated with both Congo red and the dinitrosalicylic acid reagent methods. Based on qualitatively assays, sixteen of the isolates revealed carboxymethyl cellulose degradation ability, where the Trichoderma POS7 isolate showed the highest increase in filter paper activity, endo-1,4-β-glucanases and β-glucosidases activities (p<0.05) in a short incubation time. This isolate was molecularly identified as Trichoderma koningiopsis, based on internal transcribed spacer sequences. Our results provide new information and reveal new microorganism in the hydrolysis of cellulose material. The phylogenetic analysis revealed close positioning of T. koningiopsis clade with T. viride, T. viridescens and T. petersenii clades in a closely related group, in concordance with the current taxonomic classification of Trichoderma genus.
EFFECT OF HOUSEHOLD PROCESSING ON REMOVAL OF MULTI-CLASSES OF PESTICIDES FROM TOMATOES
Authors: Ajeep Lima , Alnaser Zakaria , Tahla Mohammad Kheir
Published: April 2021

In this paper, twenty-two pesticide residues were monitored in tomatoes.72 marketed samples were extracted and purified with QuEChERS method, and analyzed with liquid and gas Chromatography. The mean recoveries ranged from 90.75%to105.31%. The relative standard deviation was 1% to 7.5%. The limits of detection and quantification ranged from 0.0004 to 0.0231 mg.kg−1 and 0.0012 to 0.0693 mg.kg−1, and good linearity was obtained. Out of total analyzed samples, 34 samples (47.22%) were contaminated with tested pesticide residues; out of which 10 samples (13.89%) exceeded the maximum residue limits.
The effects of four processing techniques (washing with tap water, washing with solution of acetic acid, peeling and boiling) on the residual pattern of five insecticides (dimethoate, carbaryl, chlorpyrifos, cypermethrin and fenvalerate) and one herbicide (2,4 dichlorophenoxy acetic acid (2,4D)) were evaluated. The reaction of the pesticides depends obviously on the physico-chemical features and also on the systemic character of the pesticides. Both of the washings lowered clearly the residues for all detected pesticides with removing up to 63.08%. Peeling was found to totally remove the residues of fenvalerate, carbaryl, cypermethrin and chlorpyrifos. Results obtained from the boiling indicated that a complete removal of 2,4D and dimethoate residues was finally achieved. In addition to that, the concentrations of cypermethrin and fenvalerate increased and processing factors above 1 were observed, the results can be seen as valuable base for monitoring of pesticides in tomatoes and supply more comprehension of residue demeanor after household processing. These implementations are important to protect consumer health from the damage of pesticide residues in food.