bluuebunny/crossref_metadata_2025 huggingface dataset:
HPV DNA Testing and Mobile Colposcopy for Cervical Precancer Screening in HIV Positive Women: A Comparison Between Two Settings in Ghana and Recommendation for Screening
Authors: Effah Kofi , Anthony Richard , Tekpor Ethel , Amuah Joseph E. , Wormenor Comfort M. , Tay Georgina , Kraa Smith E. Y. , Katso Angela M. , Akonnor Christiana A. , Kemawor Seyram , Danyo Stephen , Atuguba Bernard H. , Essel Nana Owusu M. , Akakpo Patrick K.
Published: April 2024

Introduction

Women living with HIV (WLHIV) have higher prevalence and persistence rates of high-risk human papillomavirus (hr-HPV) infection with a six-fold increased risk of cervical cancer. Thus, more frequent screening is recommended for WLHIV.

Objectives

This retrospective descriptive cross-sectional study was conducted to investigate and compare the prevalence of hr-HPV infection and abnormal findings on mobile colposcopy in two cohorts of WLHIV following cervical screening in rural and urban settings in Ghana.

Methods

Through the mPharma 10 000 Women Initiative, WLHIV were screened via concurrent hr-HPV DNA testing (MA-6000; Sansure Biotech Inc., Hunan, China) and visual inspection (Enhanced Visual Assessment [EVA] mobile colposcope; MobileODT, Tel Aviv, Israel) by trained nurses. The women were screened while undergoing routine outpatient reviews at HIV clinics held at the Catholic Hospital, Battor (rural setting) and Tema General Hospital (urban setting), both in Ghana.

Results

Two-hundred and fifty-eight WLHIV were included in the analysis (rural, n = 132; urban, n = 126). The two groups were comparable in terms of age, time since HIV diagnosis, and duration of treatment for HIV. The hr-HPV prevalence rates were 53.7% (95% CI, 45.3–62.3) and 48.4% (95% CI, 39.7–57.1) among WLHIV screened in the rural vs urban settings ( p-value = .388). Abnormal colposcopy findings were found in 8.5% (95% CI, 5.1–11.9) of the WLHIV, with no significant difference in detection rates between the two settings ( p-value = .221). Three (13.6%) of 22 women who showed abnormal colposcopic findings underwent loop electrosurgical excision procedure (LEEP), leaving 19/22 women from both rural and urban areas with pending treatment/follow-up results, which demonstrates the difficulty faced in reaching early diagnosis and treatment, regardless of their area of residence. Histopathology following LEEP revealed CIN III in 2 WLHIV (urban setting, both hr-HPV negative) and CIN I in 1 woman in the rural setting (hr-HPV positive).

Conclusions

There is a high prevalence of hr-HPV among WLHIV in both rural and urban settings in this study in Ghana. Concurrent HPV DNA testing with a visual inspection method (colposcopy/VIA) reduces loss to follow-up compared to performing HPV DNA testing as a standalone test and recalling hr-HPV positive women for follow up with a visual inspection method. Concurrent HPV DNA testing and a visual inspection method may also pick up precancerous cervical lesions that are hr-HPV negative and may be missed if HPV DNA testing is performed alone.
Evaluating of Existing VTE Risk Scales in Glioma Patients
Authors: Maria Simakova , Konstantin Pishchulov , Vitaliy Lukinov , Nikita Voynov , Maria Bulaeva , Olga Melnichnikova , Yulia Zhilenkova , Аnna Savelyeva , Olga Moiseeva , Konstantin Samochernykh
Published: April 2024

Introduction

Postoperative venous thromboembolism (VTE) is a frequently occurring complication among glioma patients. Several risk assessment models (RAMs), including the Caprini RAM, the IMPROVE Risk Score, the IMPROVED VTE Risk Score, and the Padua Prediction Score, have not been validated within the glioma patient population. The purpose of this study was to assess the predictive accuracy of established VTE risk scales in patients with glioma.

Materials and Methods

A single-center, retrospective, observational cohort study was conducted on 265 glioma patients who underwent surgery at the Almazov Medical and Research Centre between 2021 and 2022. VTE detection followed the current clinical guidelines. Threshold values for the Caprini, IMPROVE VTE, IMPROVEDD, and Padua scales were determined using ROC analysis methods, with cumulative weighting for sensitivity and specificity in predicting VTE development. The areas under the ROC curves (AUC) were calculated, and comparisons were made using the DeLong test.

Results

The area under the curve for the Caprini risk assessment model was 80.41, while the IMPROVEDD VTE risk score was 75.38, the Padua prediction score was 76.9, and the IMPROVE risk score was 72.58. No significant differences were observed in the AUC values for any of the scales. The positive predictive values of all four scales were low, with values of 50 (28–72) for Caprini, 48 (28–69) for IMPROVEDD VTE, 50 (30–70) for Padua, and 64 (35–87) for IMPROVE RAM. No significant differences were found in terms of PPV, NPV, positive likelihood ratio, and negative likelihood ratio among the analyzed scales.

Conclusions

The Caprini Risk Assessment Model, the IMPROVE Risk Score, the IMPROVED VTE Risk Score, and the Padua Prediction Score exhibit acceptable specificity and sensitivity for glioma patients. However, their low positive predictive ability, coupled with the complexity of interpretation, limits their utility in neurosurgical practice.
Dynamics modeling of urban rail vehicle axle-box bearings with roller defect considering time-varying impact
Authors: Yu Yaoxiang , Zhang Ruiqi , Guo Liang , Chen Zaigang , Gao Hongli , Zhang Guoli
Published: April 2024

Accurately simulating the vibration response of the axle-box bearing with a localized defect on the roller can guide the proposal of several health condition estimation methods. However, there is still a lack of discussion and analysis on the detailed motion process of the roller defect passing through the inner/outer race. For filling this gap, a roller defect model considering time-varying impact is proposed and applied to the vehicle–track coupling system considering axle-box bearings. In addition to the Hertz contact force due to the relative displacement between the roller and race, time-varying impact excitation is designed according to the law of the conservation of energy. At first, an onsite test and an experimental test are implemented to validate the accuracy of the roller defect model and the vehicle–track coupling model, respectively. Then, the effect of the roller defect on the vibration characteristics of the components in the vehicle system is investigated. Finally, the influence of the defect size and vehicle speed on the vibration response of the axle-box bearing is studied, and the change rule of the time-varying impact is also researched with the defect size. Besides, the axle-box vibration response is simulated under variable vehicle speeds, and order tracking technique is applied to analyze the simulated result.
Diagnostic Performance of Node Reporting and Data System Magnetic Resonance Imaging Score in Detecting Metastatic Cervical Lymph Nodes of Nasopharyngeal Carcinoma
Authors: Yang Xinggang , Yang Jiaqing , Li Jia , Leng Junyan , Qiu Yu , Ma Xuelei
Published: April 2024

Background:

The Node Reporting and Data System (Node-RADS) is a recently proposed classification system for the categorization of lymph nodes in radiological images. This study was conducted to retrospectively evaluate the diagnostic accuracy of the Node-RADS score for metastatic cervical lymph nodes on magnetic resonance imaging (MRI) of patients with nasopharyngeal carcinoma (NPC).

Methods:

We retrospectively analyzed cervical lymph nodes of NPC cases. Two radiologists independently evaluated each lymph node on the MRI scans using Node-RADS. Interobserver agreement between 2 radiologists for Node-RADS score assessment was evaluated by linear weighted kappa statistics. The correlation between metastasis and the Node-RADS score of each lymph node was analyzed using multivariate regression analysis. To investigate the diagnostic performance of the Node-RADS score, we further conducted receiver operating characteristic curve analysis. Correspondently, the sensitivity, specificity, positive predictive value, and negative predictive value of each different cutoff (>1, >2, >3, and >4) were computed.

Results:

In all, 119 patients with NPC were assessed, including 203 cervical lymph nodes consisting of 140 (69%) of 203 metastatic and 63 (31%) of 203 benign. The kappa agreement between the 2 readers for the Node-RADS score was 0.863 (95% CI = 0.830-0.897, P < .001). Node-RADS score on MRI scan was shown to be an independent predictive factor of lymph node metastasis after multivariate regression analysis (odds ratio [OR] = 6.745, 95% CI = 3.964-11.474, P < .001). Node-RADS achieved an area under the curve (AUC) of 0.950 (95% CI = 0.921-0.979) in diagnosing metastatic lymph nodes. When Node-RADS >2 was identified as the best cutoff based on balanced values, the sensitivity and positive predictive value were 0.92 and 0.94, respectively.

Conclusions:

Our study suggests that the Node-RADS score has high accuracy in predicting NPC cervical lymph node metastasis. Nevertheless, this conclusion requires confirmation in a larger cohort of patients with NPC.
The long now and liminality: will we create communitas? A macro-social perspective of COVID-19
Authors: Macnamara Jim
Published: April 2024

The ways in which the COVID-19 pandemic has changed society are the source of widespread discussion. But references to a ‘new normal’ are mostly confined to hybrid working and a possible four-day working week. Should future-scoping remain so narrow, a major opportunity for fundamental rethinking will be lost. This commentary seeks to take up and expand the argument of a 2021 article on the effects of COVID-19 by exploring the wider social implications and the opportunity presented by this existential crisis. Specifically, this critical analysis explores whether COVID-19 and its impacts have created a moment of liminality – a time of “transition during which the normal limits to thought are relaxed, opening the way to novelty and imagination, construction, and destruction” potentially leading to what Victor Turner refers to as communitas in which we can rethink the issues of our time and in which new social structures and understandings can form.
The permanency of mass atrocities: The fallacy of ‘never again’?
Authors: Gallagher Adrian , Illingworth Richard , Raffle Euan , Willis Ben
Published: April 2024

The terminology of ‘never again’ has been studied in Sociology, Cultural Studies and History, yet remains neglected in International Relations. This is despite its centrality in debates over humanitarian intervention, the Responsibility to Protect and mass atrocity prevention. To foster a conversation over the term’s use, this article uses an interdisciplinary approach to show how the meaning of ‘never again’ has changed over time. Building on this, we analyse five real-world problems: (1) the quantitative problem, (2) the nuclear problem, (3) the regime change problem, (4) the weak state problem and (5) the P5 problem. We find the blanket call of ‘never again’ oversimplifies the complexity of mass atrocity prevention and creates an unrealistic goal. Going forward, we call on those invoking the phrase to explain what they mean by it and why they are using it as part of a broader reassessment of the term’s use in International Relations.
‘Entrapped in a penal time capsule’: Extralegal discourses in sentence review of life prisoners in India
Authors: Tripathi Karan , Dagan Netanel
Published: April 2024

Scholars argue that lifers’ parole can be mobilised to be punitive and politicised. However, how parole decision-makers construct and disguise their punitive and politicised discourses when deciding the paroled subject is understudied, especially with regard to the global south. In this paper, based on content analysis of the dossiers of Delhi's Sentence Review Board (SRB) during 2018–2021, and in-depth interviews with the SRB members, we found that most of the SRB's rejections were solely based on the crime, a violation of a lifers right to a meaningful consideration for premature release. The SRB members rationalise their decision-making through two discourses: ‘temporal entrapment’, and ‘disguised punitivism’. Through these discourses, the SRB exercises penal power which is formally unified by the legal scaffolding but discursively bifurcated, for negotiating competing penal and political values and logics.
Evolution of variable angle tow composite structures: Data analysis and relevance of the theme
Authors: Maciel Maisa Milanez Ávila Dias , Amico Sandro , Guedes Rui Miranda , Tita Volnei
Published: April 2024

Variable angle tow composites were developed to increase stiffness in notched laminates. Scientific advancements in manufacturing and fiber path optimization have since improved variable angle tow composites. This study uses bibliometric analysis to track the evolution of variable angle tow composites in the literature. Bibliometric analysis is a useful tool for measuring paper contributions and accurately assessing performance, aiding authors in the research process. This article presents a co-occurrence map of keyword frequency in research papers. Furthermore, an experimental section highlights manufacturing defects found in variable angle tow composites produced by filament winding, showing that manufacturing real structures in variable angle tow composites poses a significant challenge. Lastly, the perspectives of variable angle tow composite applications are discussed.
A sustainable and energy efficient approach for development of electrically conductive materials and their characterizations
Authors: Bashir Khalid , Gupta Dheeraj , Jain Vivek
Published: April 2024

In this study, composite castings of electrically conductive materials were prepared using electromagnetic energy of frequency 2.45 GHz. Three separate sets of castings were produced inside the domestic microwave applicator cavity, with reinforced compositions of up to 15% in steps of 5% for each composite cast (copper (Cu) + 5% molybdenum (Mo), Cu + 10% Mo, and Cu + 15% Mo). A microwave radiation exposure time of 12 min was required for the complete melting of pure copper powder. However, the addition of Mo reinforcement caused a reduction in exposure time to 11.33 min (min) for the Cu-15% Mo composite cast. The formation of different phases was revealed by the X-ray diffraction analysis of the cast samples. Only a 0.92% copper oxide phase was detected in the pure copper cast samples. The composite cast samples exhibited peaks corresponding to Cu64O, Cu6Mo5O18, and MoO2. Microstructure analysis demonstrated that the grains grew in an equiaxed manner with a uniform dispersion of the reinforcements. The maximum microhardness achieved is 99.2 ± 4.99 Hv for Cu + 15% Mo which is 1.66 times better than microwave-cast copper sample.
Co-operative inquiry: Qualitative methodology transforming research ‘about’ to research ‘with’ people
Authors: Russ Erica , Petrakis Melissa , Whitaker Louise , Fitzroy Robyn , Short Monica
Published: April 2024

Co-operative inquiry, pioneered by Heron and Reason, is a qualitative, participatory methodology that powerfully transforms research from inquiring about people to inquiring with people. Contemporary qualitative research is increasingly trending from studying others to engaging all participants in research processes as equal collaborators. Consequently, many qualitative researchers are looking to participatory methodologies such as co-operative inquiry to create authentic research partnerships between researchers, professional practitioners and people with lived experience. This methodology engages participants in the entire research process as co-researchers, co-inquirers, co-participants and co-authors, generating new knowledge by analysing rich understandings of people and their experiences. This article analyses and self-evaluates four co-operative inquiries. They demonstrate the utility, accessibility and knowledge base of the methodology, its ethical strengths, and how it is particularly appropriate for fostering co-design and co-production by eliciting varied and broad perspectives regarding complex phenomena.
In-stent Restenosis After Stenting for Superior Mesenteric Artery Dissection Is Associated With Stent Landing Zone: From Clinical Prediction to Hemodynamic Mechanisms
Authors: Mei Junhao , Yan Hui , Zhao Xi , Yuan Yuan , Su Haobo , Xue Tongqing , Jia Zhongzhi
Published: April 2024

Objective:

To identify risk factors for in-stent restenosis (ISR) in patients undergoing stent placement for superior mesenteric artery dissection (SMAD) and to determine the hemodynamic mechanism underlying ISR.

Methods:

For this retrospective study, patients with SMAD who had ISR after stent placement were included in the ISR group, and age- and sex-matched patients with SMAD who did not experience ISR after stent placement were included in the control group. Clinical, imaging, and hemodynamic data were assessed. Multivariable regression was used to identify independent ISR risk factors. Structural and fluid dynamics simulations were applied to determine the hemodynamic mechanism underlying the occurrence of ISR.

Results:

The study population included 26 patients with ISR and 26 control patients. Multivariate analysis demonstrated that stent-to-vascular (S/V) ratio (odds ratio [OR], 1.14; 95% confidence interval [CI]: 1.00–1.29; p=0.045), stent proximal position >10 mm away from the SMA root (OR, 108.67; 95% CI: 3.09–3816.42; p=0.010), and high oscillatory shear index (OSI) area (OR, 1.25; 95% CI: 1.02–1.52; p=0.029) were predictors of ISR. In structural and fluid dynamics simulations, a stent proximal position near the abdominal aorta (AA) or entering into the AA reduced the contact area between the proximal struts of the stent and the vascular wall, and alleviated the distal lumen overdilation.

Conclusion:

The S/V ratio, stent proximal position away from the SMA root (>10 mm), and high OSI area are independent risk factors for ISR in patients with SMAD undergoing stent placement. Deploying the proximal end of the stent near the AA or entering into the AA appears to improve the hemodynamic environment in the SMA lumen and ultimately reduce the risk of ISR.

Clinical Impact

In-stent restenosis is an uncommon but potentially catastrophic complication after stent placement for the management of superior mesenteric artery dissection. This study identified risk factors for in-stent restenosis and demonstrated that, as long as the stent can fully cover the dissection range, deploying the proximal end of the stent near the abdominal aorta or less entering into the abdominal aorta may reduce the risk of in-stent restenosis in this patient population.
Preclinical Evaluation of a Modular Inner-Branched Stent Graft to Reconstruct the Left Subclavian Artery in Thoracic Endovascular Aortic Repair: Experimental Study in Pigs
Authors: Jia Senhao , Zhang Hongpeng , Jia Xin , Xiong Jiang , Ma Xiaohui , Xu Yongle , Zhang Minhong , Rong Dan , Guo Wei
Published: April 2024

Purpose:

In approximate 40% of thoracic endovascular aortic repair (TEVAR) procedures, the left subclavian artery (LSA) needs to be covered to obtain sufficient proximal sealing zone. To preserve the LSA during the TEVAR for type B aortic dissection (TBAD) adjacent to LSA, our team designed a modular single inner-branched stent graft. This study was performed to evaluate the safety and feasibility of deploying a modular single inner-branched stent graft in a porcine model.

Materials and Methods:

Modular inner-branched stent grafts were implanted in 14 pigs via right femoral and right carotid arterial access. Computed tomography angiography (CTA) and angiography were performed in all pigs to appraise the morphological characteristics of the stent grafts at the end of follow-up. The pigs were then euthanized, and tissues were collected for gross and histological examination.

Results:

The technical success rate was 100% (14/14). One pig suddenly died 5 hours after operation, and 1 pig died after completing the follow-up CTA. During the follow-up period, all surviving pigs showed good mental state, normal diets and activities. Computed tomography angiography examinations showed that all stent grafts were intact without fracture. All bridging covered stents were patent. Angiography showed that the position, shape, and adhesion of the stent grafts were good, and no obvious endoleaks were found. Histological examination showed that the biocompatibility of the stent grafts was good.

Conclusions:

This study’s outcomes demonstrate that it is safe and feasible to deploy a modular single inner-branched stent graft in a porcine model.

Clinical Impact

This device is the first modular device designed to treat TBAD adjacent to LSA in China. This device is a modular two-component system consisting of a thoracic aortic stent graft with a retrograde inner branch and a bridging covered stent. The modular design and the retrograde inner branch are the two important innovations of this device. Theoretically, the device could make it easier and safer for clinicians to treat TBAD adjacent to the LSA.
Correlation Between ImageJ and Conventional Manual Scoring Methods for Programmed Death-Ligand 1 Immuno-Histochemically Stained Sections
Authors: Al Taher Rand Suleiman , Abbas Manal A. , Halahleh Khalid , Sughayer Maher A.
Published: April 2024

Background: One of the most frequently used methods for quantifying PD-L1 (programmed cell death-ligand 1) expression in tumor tissue is IHC (immunohistochemistry). This may predict the patient's response to anti-PD1/PD-L1 therapy in cancer. Methods: ImageJ software was used to score IHC-stained sections for PD-L1 and compare the results with the conventional manual method. Results: In diffuse large B cell lymphoma, no significant difference between the scores obtained by the conventional method and ImageJ scores obtained using the option “RGB” or “Brightness/Contrast.” On the other hand, a significant difference was found between the conventional and HSB scoring methods. ImageJ faced some challenges in analyzing head and neck squamous cell carcinoma tissues because of tissue heterogenicity. A significant difference was found between the conventional and ImageJ scores using HSB or RGB but not with the “Brightness/Contrast” option. Scores obtained by ImageJ analysis after taking images using 20 × objective lens gave significantly higher readings compared to 40 × magnification. A significant difference between camera-captured images’ scores and scanner whole slide images’ scores was observed. Conclusion: ImageJ can be used to score homogeneous tissues. In the case of highly heterogeneous tissues, it is advised to use the conventional method rather than ImageJ scoring.
First-Year College Achievement and Graduation Rates for Hispanic and Hispanic First-Generation Students
Authors: Vaughan Angela L. , Martell Jordan L. , Dixon Brianne T. , French Emma A.
Published: April 2024

To increase persistence, many universities provide first-year seminars (FYS) for entering students. Although there have been consistent positive outcomes for FYS participants, many times, the research is based on short-term outcomes, or less rigorous analysis. This study assessed short- and long-term outcomes for Hispanic ( n = 456) and Hispanic first-generation students ( n = 350) who participated in a research-based academic FYS. FYS participants had significantly higher outcomes in first-term GPA, 1-year persistence and graduation rates.
Based on ACF-CFRP composite energy absorbing material protection clothing designing for the elderly with degenerative imbalance
Authors: Zhao Shifan , Shen Lei , Liu Chuyue , Chen Han
Published: April 2024

With the progression of age, the risk of falls in the elderly population escalates. Hip fractures are perceived as one of the most severe consequences of such falls and are often described as “the last fracture in one’s life,” with mortality rates reaching 20%−30% and accompanied by a significant rate of disability. To address this pressing issue, our study conducted an in-depth analysis of the mechanical properties of Artificial Cartilage Foam (ACF) and Carbon Fiber Reinforced Polymer (CFRP). Based on this research, we devised a laminated structure where ACF acts as the outer layer, with CFRP positioned centrally, capitalizing on the material’s intrinsic shock-absorbing attributes. Building on this structure, based on this structure, a specialized protective clothing design tailored for the elderly to counteract age-related balance impairments is proposed. Furthermore, we undertook experiments to gage user anxiety levels and assess the wearability comfort of the attire. Our findings indicate that this protective garment can effectively absorb the impact energy generated during falls, significantly reducing the risk of injury in the elderly. Additionally, its ergonomic design helps alleviate the psychological distress elderly individuals may experience due to the fear of falling. This research presents an innovative and effective strategy for enhancing fall protection in the elderly demographic.
Load sensitive control characteristics of a novel two-dimensional pulse width modulated variable mechanism
Authors: Jian Wu , Jian Ruan , Yan Ren
Published: April 2024

Load sensing technology is a typical hydraulic technology that automatically meets load requirements by adjusting the pressure and flow at the pump outlet. Traditional load sensitive pump control systems rely on variable mechanisms to achieve such flow control characteristics. However, general variable mechanisms have complex structures and poor dynamic performance if frequently adjusted. Therefore, a new variable mechanism, named two-dimensional pulse width modulation rotary valve, is proposed. Different from the pulse width modulation control method of the electronic technology, the two-dimensional pulse width modulation rotary valve conducts secondary distribution of the quantitative pump output in the way of fluid pulse width modulation: the valve core rotates to generate discrete fluid, and the axial sliding of the valve core controls the duty ratio of the discrete fluid. The dynamic balancing of the axial displacement is controlled by feedback pressure to provide a fixed differential pressure for the control valve, achieving that the flow through the control valve is uniquely controlled by the valve opening of the control valve. The principle of the fluid pulse width modulation is first introduced, and then the mathematical model of the proposed variable mechanism and the corresponding system is established. Simulation analysis is implemented. Finally, the effectiveness of the load sensing system controlled by a two-dimensional pulse width modulation rotary valve is verified by the experiment.
Barriers and enablers to accessing child health resources and services: Findings from qualitative interviews with Arabic and Mongolian immigrant mothers in Australia
Authors: Jawad Danielle , Wen Li Ming , Rissel Chris , Baur Louise , Mihrshahi Seema , Taki Sarah
Published: April 2024

Background:

Over the past two decades, there has been an increase of immigrants in Australia. Despite this, the availability of culturally responsive resources and services that cater to their needs remains insufficient.

Objective:

The aim of this study was to explore the resources used and trusted by Mongolian- and Arabic-speaking migrant mothers in Australia for child health information and examine how they navigate and overcome challenges they encounter accessing this information.

Design:

Semi-structured telephone interview

Methods:

A theory informed semi-structured 60-min telephone interview was conducted in Arabic and Mongolian with 20 Arabic- and 20 Mongolian-speaking migrant mothers of children younger than 2 years or currently pregnant and living in Australia. Data were analysed thematically using the framework method.

Results:

The reliance on digital platforms such as google emerged as a common trend among both groups of mothers when seeking child health information. Notably, there were differences in resources selection, with Mongolian mothers showing a preference for Australian-based websites, while Arabic-speaking mothers tended to opt for culturally familiar resources. There were various barriers that hindered their access to health services and resources, including language barriers, cost, and limited knowledge or familiarity with their existence. Negative encounters with healthcare professionals contributed to a perception among many mothers that they were unhelpful. Both groups of mothers employed a cross-checking approach across multiple websites to verify trustworthiness of information. Acculturation was shown only among the Mongolian-speaking mothers who adapted their cultural practices in line with their country of residence.

Conclusion:

The findings of this study highlight the importance of addressing the needs of migrant mothers in accessing child health information. Health professionals, government agencies, and researchers have an opportunity to provide culturally responsive support by fostering a culturally inclusive approach to developing and promoting equitable access to services and resources, ultimately enhancing the wellbeing of migrant families.
When stimulus variability accelerates the learning of task knowledge in adults and school-aged children
Authors: Yanaoka Kaichi , van‘t Wout Félice , Saito Satoru , Jarrold Christopher
Published: April 2024

Experience with instances that vary in their surface features helps individuals to form abstract task knowledge, leading to transfer of that knowledge to novel contexts. The current study sought to examine the role of this variability effect in how adults and school-aged children learn to engage cognitive control. We focused on the engagement of cognitive control in advance (proactive control) and in response to conflicts (reactive control) in a cued task-switching paradigm, and conducted four preregistered online experiments with adults (Experiment 1A: N = 100, Experiment 1B: N = 105) and 9- to 10-year-olds (Experiment 2A: N = 98, Experiment 2B: N = 97). It was shown that prior task experience of engaging reactive control makes both adults and 9- to 10-year-olds respond more slowly in a subsequent similar-structured condition with different stimuli in which proactive control could have been engaged. 9- to 10-year-olds (Experiment 2B) exhibited more negative transfer of a reactive control mode when uninformative cue and pre-target stimuli, which do not convey task-relevant information, were changed in each block, compared with when they were fixed. Furthermore, adults showed suggestive evidence of the variability effect both when cue and target stimuli were varied (Experiment 1A) and when uninformative cue and pre-target stimuli were varied (Experiment 1B). The collective findings of these experiments provide important insights into the contribution of stimulus variability to the engagement of cognitive control.
Pre-crastination across physical and cognitive tasks
Authors: David Adi , Ingwu Justyne , Meselsohn Nicole , Retzloff Clara , Hutcheon Thomas G
Published: April 2024

Pre-crastination refers to the tendency to begin a task as soon as possible, even at the cost of additional effort. This phenomenon is consistently observed in tasks in which participants are asked to select one of two buckets to carry to a target. Surprisingly, on a high proportion of trials participants choose the bucket that is closer to them (and further from the target) as opposed to the bucket that is further from them (and closer to the target). In other words, participants tend to complete the task of picking up a bucket as soon as possible, even when this requires additional physical effort. The purpose of the current experiment was to test whether an individual’s tendency to pre-crastinate is stable across tasks. Participants performed a physical load task where they selected one of two buckets to carry to a target. The same participants performed a cognitive load task where they picked up number strings at one of the two bucket locations and mentally carried the number string to a target. We found that participants pre-crastinated in both tasks and this tendency was reduced as task difficulty increased. Importantly, we found a significant association between an individual’s tendency to pre-crastinate in the physical load task and their tendency to pre-crastinate in the cognitive load task. Thus, an individual’s tendency to pre-crastinate is consistent across tasks and suggests that this is a stable characteristic of how individuals choose to order tasks.
Adaptations within female US Olympic swimming medalists’ competition-day routines: A mixed-methods approach
Authors: Grant Matthew A. , Schempp Paul G. , Tobin Grant J.
Published: April 2024

The purpose of this study was to examine adaptations within competition day routines of female US Olympic medalists in differently formatted competitions in order to locate changes based on the organizations of the swimming competitions and differentiate the inflexible from the flexible parts of the routines. A purposeful sample of six elite swimmers participated in two 1-hour interviews with an observation at a national-level competition. A mixed-methods analysis protocol helped locate adaptions within the routine. Four results of note were reported. First, adaptations outside venue depended on format and/or individual schedule; adaptations inside the venue were in response to how they felt and their surroundings. Second, participants adapted their competition-day routines at different levels, i.e., segment and behavior levels, depending on being outside or inside the venue, respectively. Third, the competition-day routine of the participants followed similar competition-day routine segments at the venue that matched in scope and sequence for both the prelims and finals sessions. Fourth, once at the venue, adaptation of behaviors changed in order to accomplish the necessary active or passive preparations without changing the scope, sequence and duration of the segments. These findings deepen the understanding of competition-day routines by locating flexible and inflexible parts of the routines and showing greater variance when athletes adapt their routines.
Mapping talent pathways: A comparative study of developmental activities and practice structure in Brazilian and Spanish U-18 elite youth male soccer players
Authors: Machado Guilherme , González-Víllora Sixto , Pastor-Vicedo Juan Carlos , Teoldo Israel
Published: April 2024

The purpose of this study was threefold: (1) to compare the engagement in various types and amounts of soccer activities during childhood and adolescence between Brazilian and Spanish elite youth soccer players; (2) to test what talent development pathway characterizes youth development in elite soccer in Brazil and Spain and (3) to compare the practice structure between elite youth soccer in Brazil and Spain. Participants were 131 U-18 elite male soccer players from Brazil ( n = 68) and Spain ( n = 63) competing in the national league. The Participant History Questionnaire was used to measure the soccer activities undertaken by players. Developmental activities were analyzed for two age periods: childhood (6–12 y/o) and early adolescence (13–15 y/o). In Spain, players started their involvement in practice and competition in soccer earlier compared to Brazilian players ( p < .05). Brazilian players were more involved in structured activities, such as practice in soccer and futsal, and participated in a greater number of sports in childhood and early adolescence ( p < .05). We found a very similar percentual practice structure (individual, pair, drills, group tactics and collective tactics activities) between Spain and Brazil, although Brazilian players accumulated a greater practice volume. It is concluded that Spanish and Brazilian U-18 elite youth male soccer players were differentiated by their milestones in soccer and their engagement in practice activities during childhood and early adolescence. Talent development pathway of male soccer players in Spain was characterized by the early engagement pathway, while the Brazilian system was characterized by the specialized sampling model.
A multi-institutional update on surgical outcomes after penile silicone sleeve implantation
Authors: Siegal Alexandra R. , Celtik Kenan E. , Razdan Shirin , Sljivich Michaela , Kansas Bryan , Shah Bhavik , Levine Laurence A. , Valenzuela Robert J.
Published: April 2024

Background:

The increasing popularity of the silicone sleeve penile implant has been accompanied by concerns over potential risks and adverse events.

Objectives:

To provide multi-institutional data on safety outcomes in patients undergoing silicone sleeve penile implant surgery across high-volume implant surgeons. In addition, we discuss preventative techniques to minimize postoperative complications and the management of these events.

Design and methods:

We performed a retrospective analysis of men undergoing penile silicone sleeve implants between November 2020 and November 2022 with four surgeons, each from a separate institution. Perioperative and postoperative adverse events, including unsatisfactory cosmetic outcomes requiring revision, were determined by physician follow-up. Flaccid penile length and girth were measured preoperatively and postoperatively.

Results:

A total of 299 male patients underwent silicone sleeve implant surgery, with an average age of 42.5 ± 10.5 years and an average body mass index of 28.5 ± 4.0. The patient cohort exhibited minimal comorbidities, with 5% having hyperlipidemia, 2% being smokers, 2% having cardiovascular disease, and 1% having diabetes. Patients experienced an average increase of 4.1 ± 1.5 cm in their flaccid penile length (a 50% increase) and an average increase of 3.4 ± 1.5 cm in their flaccid girth (a 37% increase) ( p < 0.01). Complication rates included new-onset postoperative erectile dysfunction (0%), infection (1.3%), seroma (2.0%), and erosion (5.0%). The average follow-up time was 11.6 months. Notably, our rates of infection and seroma were lower than those reported in a previous single-center review, while erosion rates were higher.

Conclusion:

This is the largest study to characterize the safety of the penile silicone sleeve implant across multiple institutions. In men who desire cosmetic size augmentation, silicone sleeve implant surgery is associated with significantly increased flaccid penile length and girth. Complications are mainly cosmetic and may be corrected; however, patients should be appropriately counseled on the risk of erosion, which appears to be higher than previously reported.
Clinical features in rotator cuff calcific tendinopathy: A scoping review
Authors: Guido Federico , Venturin Davide , De Santis Andrea , Giovannico Giuseppe , Brindisino Fabrizio
Published: April 2024

Introduction

The main goal of this scoping review is to highlight the clinical features of subjects with rotator cuff calcific tendinopathy (RCCT), in order to identify and map this condition clinical criteria, and thus to be able to hypothesize such pathology before imaging investigations.

Methods

Four databases were consulted up to January 2023. The obtained results were reported following the PRISMA-ScR and the Joanna Briggs Institute reviewer's manual was used as guideline for conducting the review. No time and geographical restrictions were applied.

Results

A total of 851 records have been identified, with 50 studies meeting the inclusion criteria. Subjects with RCCT mostly reported nightly, acute and severe pain with spontaneous onset. Symptoms were mostly unilateral. Subjects were mostly women aged between 30 and 60. Deficit in active and passive range of motion was reported, mainly during abduction and forward flexion. Endocrine and metabolic disorders were described as comorbidity, in particular diabetes and thyroid disorders.

Conclusion

In this scoping review, the most relevant RCCT clinical features were detected. These clinical criteria, predictive for shoulder RCCT, can be crucial to help all clinicians suspect this musculoskeletal disease early and with certainty, thus allowing for an appropriate and prompt diagnosis path.

Level of evidence

III.
Assessing the Relationship Between Compulsory Voting and the Over-Representation of Extreme Parties
Authors: Ankudinov Ivan A.
Published: April 2024

In this paper, we address the issue of partisan bias in compulsory voting systems. Given the current global trends – declining trust in mainstream political parties, rising support for left- and right-wing radicals, growing populism and anti-elite sentiment – we seek to determine how they manifest themselves in an environment where citizens are required to vote by law. To answer this question, a quasi-experimental design is proposed. The data show that forced activity does not affect either extreme forces support rates (from a cross-country perspective) or the rationality of their voters (from an individual-level perspective). As far as we know, this is the first attempt to generalize the role of compulsory voting in extreme politics, as well as the first one to refute this role with ample evidence.
Enriching Minds: The Gifted Education Landscape in the Syrian Arab Republic
Authors: Al-Raeei Marwan , Azmeh Chadi , AlDakak Hala
Published: April 2024

Promoting the education of talented and gifted students is a crucial aspect of establishing a strong society focused on scientific knowledge. This praxis article delves into the implementation of strategies in the Syrian Arab Republic to support and identify gifted students, focusing on initiatives such as the Syrian Scientific Olympiad, the National Centre for Distinguished Students, and Academic Programs for Distinguished Students. Data collection methods utilized in this study shed light on the outcomes of these initiatives and measures taken to promote gifted education in Syria. The analysis of this data provides insights into the impact of these programs on gifted students in crisis-stricken regions. The study emphasizes the significant role played by the Distinction and Creativity Agency in nurturing exceptional talents and fostering personal growth. Overall, the support provided to gifted students contributes to cognitive advancement, psychological well-being, and skill development, enhancing their overall well-being and paving the way for successful futures. The government's commitment to supporting gifted education in the Syrian Arab Republic reflects its dedication to promoting talent and creativity in the Arab region.
Feasibility and Performance of Continuous Glucose Monitoring to Guide Computerized Insulin Infusion Therapy in Cardiovascular Intensive Care Unit
Authors: Ang Lynn , Lin Yu Kuei , Schroeder Lee F. , Huang Yiyuan , DeGeorge Christina A. , Arnold Patrick , Akanbi Folake , Knotts Sharon , DuBois Elizabeth , Desbrough Nicole , Qu Yunyan , Freeman Regi , Esfandiari Nazanene H. , Pop-Busui Rodica , Gianchandani Roma
Published: April 2024

Background:

We evaluated the feasibility of real-time continuous glucose monitoring (CGM) for titrating continuous intravenous insulin infusion (CII) to manage hyperglycemia in postoperative individuals in the cardiovascular intensive care unit and assessed their accuracy, nursing acceptance, and postoperative individual satisfaction.

Methods:

Dexcom G6 CGM devices were applied to 59 postsurgical patients with hyperglycemia receiving CII. A hybrid approach combining CGM with periodic point-of-care blood glucose (POC-BG) tests with two phases (initial-ongoing) of validation was used to determine CGM accuracy. Mean and median absolute relative differences and Clarke Error Grid were plotted to evaluate the CGM accuracy. Surveys of nurses and patients on the use of CGMs experience were conducted and results were analyzed.

Results:

In this cohort (mean age 64, 32% female, 32% with diabetes) with 864 paired POC-BG and CGM values analyzed, mean and median absolute relative difference between POC-BG and CGM values were 13.2% and 9.8%, respectively. 99.7% of paired CGM and POC-BG were in Zones A and B of the Clarke Error Grid. Responses from nurses reported CGMs being very or quite convenient (n = 28; 93%) and it was favored over POC-BG testing (n = 28; 93%). Majority of patients (n = 42; 93%) reported their care process using CGM as being good or very good.

Conclusion:

This pilot study demonstrates the feasibility, accuracy, and nursing convenience of adopting CGM via a hybrid approach for insulin titration in postoperative settings. These findings provide robust rationale for larger confirmatory studies to evaluate the benefit of CGM in postoperative care to improve workflow, enhance health outcomes, and cost-effectiveness.
In Vitro Analysis of Antimalarial Activity of Achillea fragrantissima (Forssk.) Sch.Bip Extracts Based on Beta-Hematin Formation
Authors: Al-Rimawi Fuad , Akkawi Mutaz , Tarayrah Hadba , Abu-Yabes Osama , Abu-Remeleh Qasem , Almutairi Hadiah , Almutairi Abdulrahman , Riaz Bushra , Alnasser Sulaiman Mohammed , Sanosi Mazahir , Alsabeelah Nimer Fehaid , Wedian Fadel , Assiri Mohammed Ail , Salman Haya Ayyal , Al-Mazaideh Ghassab M.
Published: April 2024

Introduction: The use of medicinal plants from traditional knowledge systems has increased in recent years. Achillea fragrantissima-infused water has a historical use in relieving gastrointestinal complaints and treating skin inflammations. With the rising resistance to antimalarial drugs, finding safe and affordable new drugs is crucial. Exploring medicinal plants shows promise for drug development in the fight against malaria. Methods: The objective of this research is to examine the in vitro antimalarial activity of A. fragrantissima-infused water, as well as water-ethanol extracts of its leaves, flowers, and stems based on β-hematin formation. Colorimetric semiquantitative assessments based on β-hematin inhibition and evaluation of optical density at 405 nm were employed. Results: The results demonstrated promising antimalarial activity of the different plant parts. The aqueous flower extract exhibited strong activity, comparable to that of the positive control. The leaves extract also showed strong antimalarial activity. The stem's aqueous and ethanolic extracts exhibited lower inhibitory activity compared to flowers and leaves. Synergistic antimalarial activity was observed when mixing the stem and leaves water extracts, as well as when mixing each of the stem and leaves extracts with the flower extract. The highest synergistic effect was observed when all three parts of the plant were mixed, resulting in activity comparable to the positive control. The high-performance liquid chromatography photodiode array (HPLC-PDA) chromatographic method confirmed the presence of rutin in the leaves extract. Conclusion: The findings of this study highlight the potential antimalarial activity of A. fragrantissima. The aqueous flower extract and leaves extract exhibited strong antimalarial activity, while the stem extracts showed relatively lower activity. Furthermore, synergistic effects were observed when combining different parts of the plant. These results suggest that A. fragrantissima holds promise as a potential source for the development of new antimalarial drugs. The confirmation of rutin presence in the leaves extract through HPLC-PDA analysis provides additional insights into the plant's chemical composition.