bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Payment Means: the Brazilian reality. An "Environmental Segmentation" study.
Authors: Abrantes Braga Farah Diba Mary Anni , Isabella Giuliana , Ramos Heidy Rodriguez
Published: November 2018

In the last decades, there has been a shift from the use of cash to use of electronic and digital money. There are several phases to build and overcome until the digital money reaches similar levels of cash usage. This work, through the environmental segmentation model of Almeida (2001), aims to present the main factors necessary for the viability of the use and expansion of digital payment means in Brazil. An exploratory research of the qualitative type was carried out. The method used is the case study, more specifically, a study of the sector of electronic and digital payment means. Secondary data were initially collected by collecting information from market reports and articles available in databases. Then, with a semi-structured interview script, primary data were collected. Two interviews were conducted with specialists in the segment. The benefits of using digital money will be many. The interviews highlighted that digital money would generate new revenues with intangible "products"; will allow the emergence of new markets; it may reduce maintenance costs of cash; promote digital and financial inclusion, citizenship and self-esteem. However, obstacles must be overcome: ensuring the authenticity of the transaction; laws and regulations; achieve critical mass; reduction of telecommunication costs; etc. This study benefits the management academy by exploring the technique of environmental segmentation. It addressed a theme little investigated and described in the literature, digital money. It is of utmost importance to business organizations and society to analyze the environment for the entry of digital money, as these can benefit from the new product. It is also hoped that this work will encourage study in other fields such as consumer behavior and organizational theories.
Retos y oportunidades en la implementación del tamiz neonatal para fibrosis quística
Authors: Ibarra González Isabel , Gutiérrez Morales Gabriel , Vela Amieva Marcela , Castillo Mogel José Ariel , Herrera Pérez Luz del Alba , Caamal Parra Guillermo , Herrera Maldonado Nazarea , García Flores Erika Paola
Published: November 2018

INTRODUCCIÓN: La detección temprana de la fibrosis quística mediante tamiz neonatal tiene una repercusión clínica positiva; su implementación es compleja y no existe un protocolo universal para llevarla a cabo. La cuantificación del tripsinógeno inmunorreactivo es el inicio de todos los algoritmos actuales de tamiz neonatal.OBJETIVO: Reportar los resultados preliminares de la aplicación de un algoritmo de tamiz neonatal para fibrosis quística en la Secretaría de Salud de México.MATERIAL Y MÉTODOS: Estudio retrospectivo de los resultados de la aplicación de un algoritmo de tamiz neonatal consistente en la cuantificación del tripsinógeno inmunorreactivo (IRT/IRT) seguida de la prueba del sudor para la detección de fibrosis quística en el marco del programa de tamiz metabólico neonatal de la Secretaría de Salud de México.RESULTADOS: Se obtuvieron 1,267,122 muestras aptas para el procesamiento bioquímico de sangre en papel filtro de 1,273,727 recién nacidos; 3,216 muestras resultaron con valores sanguíneos de tripsinógeno inmunorreactivo superiores al percentil 99.5. Solo en 54% de los casos se logró tomar la segunda muestra de tripsinógeno inmunorreactivo en el tiempo adecuado y se practicaron 1,787 pruebas de sudor. Se identificaron 202 casos altamente sugestivos de fibrosis quística (1:6,273 recién nacidos) que se enviaron para seguimiento médico. La gran cantidad de muestras extemporáneas favoreció el gran número de pruebas del sudor. Estos resultados permiten identificar las principales dificultades que enfrenta la implementación de este tamiz mediante el algoritmo IRT/IRT/ST.CONCLUSIÓN: La incorporación de este primer algoritmo de detección de fibrosis quística al programa de tamiz neonatal en México representa un logro, susceptible de perfección.PALABRAS CLAVE: Tamiz neonatal; fibrosis quística; CFTR; tripsinógeno inmunoreactivo; IRT.
The Force of American Modernity: World War II and the Birth of a Soft Power Superpower
Authors: Ellwood David W.
Published: November 2018

As the result of a wide debate in the US during WWII on the causes of that war, the American governing class decided that the best way to avoid yet another conflict was to export the American understanding of the link between economic progress under capitalism and the survival of liberal democracy. The Marshall Plan was the fullest expression of this world-view, launching the era of productivity and growth in Europe. But this project, renewed ideologically in the era of ‘globalisation’, began to meet increased resistance by the 1990s, as societies everywhere looked at its effects on their traditional conceptions of modernity, sovereignty and identity. While American capitalism continued to propose innovations large and small, in Europe and elsewhere their disruptive effects could set off intense political conflict. The classic example is the Uber car-sharing company.
Aproveitamento agroindustrial de resíduos de mamão 'formosa' minimamente processados
Authors: Lima Paula Cristina Carvalho , Souza Bianca Sarzi , Santini Amanda Tristão , Oliveira Daniela Costa de
Published: November 2018

O que caracteriza um dos principais entraves ao desenvolvimento da indústria de processamento mínimo de frutas e hortaliças em diversas localidades é o fato de gerar significativa quantidade de resíduos orgânicos, os quais muitas vezes, não possuem um destino específico. Em vista dessa premissa, este trabalho teve como objetivo determinar a composição centesimal de subprodutos obtidos a partir do fruto e oferecer alternativas para o aproveitamento dos resíduos de mamões minimamente processados. Do resíduo da casca foram elaboradas duas formulações de doces, em que os produtos elaborados foram avaliados quanto à composição centesimal e sensorialmente. Na avaliação sensorial foi usada escala hedônica de 5 pontos para o parâmetro sabor e aparência, e uma escala estruturada mista de 5 pontos para o parâmetro intenção de compra. Houve participação de 67 consumidores não treinados para o Doce 1 e 83 para o Doce 2. Através dos resultados, pode ser constatado que os produtos elaborados a partir da casca apresentaram bom conteúdo nutricional. O teste sensorial indicou que os produtos elaborados obtiveram boa aceitabilidade por parte dos consumidores, em que a avaliação do doce de enrolar foi mais positiva do que o doce pastoso.
Sources and dosages of Nitrogen applied with urea coated with polymers in Marandu Palisade Grass
Authors: Carvalho Fábio Janoni , Elias Renata Bernardes , Silva Adriane De Andrade , Campos Thiago Souza
Published: November 2018

Nitrogen is one of the most important nutrients for the production of forage grasses, and the most expensive one. The scope of this research was to evaluate the application of four sources of urea (conventional and coated with polymers) under different dosages, in mass production and nitrogencontent and absorption from two cuts of Brachiaria brizantha cv. Marandu. The experiment was conducted at a greenhouse in a randomized block design. The fertilizers used were conventional urea, urea covered with a polymer layer, urea covered with sulfur and urea covered with a boron and copper compound. The dosages used were 30, 60, 90 and 120 kg ha-1 of nitrogen. Fresh and dry mass, root weight and nitrogen content from first and second harvest were evaluated. On the first harvest, there was no significant difference between the treatments for the variables analyzed. On the other hand, second harvest presented difference in fresh and dry mass and nitrogen content. Regression analyses showed a linear increase with all fertilizers used, but this growth was more accentuated for the polymerized fonts. All polymerized ureas allowed higher mass production for Marandu palisadegrass, at tillering and second cut. Foliar nitrogen availability of polymerized ureas did not differ from conventional urea, being recommended to reach pastures with higher quality and productions and to decrease nitrogen losses on the system.Keywords: Brachiaria brizantha. Stabilization technologies. Sulfur polymer.
Efficacy of Alternative Cardiac Rehabilitation Delivery Formats in Improving Psychological Symptoms after Coronary Artery Bypass Grafting
Authors: Saeidi Mozhgan , Soroush Ali , Komasi Saeid , Brugnera Agostino , Patucelli Marco , Carrozzino Danilo , Fulcheri Mario , Compare Angelo
Published: November 2018

Background: Health-care systems always strive for alternative cardiac rehabilitation (CR) models to ensure that options available to patients better fit their needs, risk factor profiles, and preferences. We assessed the effects of hospital-based cardiac rehabilitation (HBCR) and hybrid cardiac rehabilitation (HCR) on psychological symptoms (i.e., anxiety, depression, and stress) among patients following coronary artery bypass graft surgery (CABG).
Methods: This cross-sectional study recruited 115 CABG patients who were referred to the Department of Cardiac Rehabilitation at Imam Ali Hospital in the Iranian city of Kermanshah between January and May 2016. The patients were assigned to 1 of the 2 programs of HBCR (26 sessions) and HCR (10 sessions). The study population’s psychological symptoms were assessed using the Depression, Anxiety, and Stress Scale (DASS) before and after the intervention, and the data were analyzed using paired t-tests and ANCOVA.
Results: A total of 105 (91%) patients concluded the CR program. Respectively, 50.8% and 26.2% of the participants in the HBCR and HCR programs were female. The mean age was 59.6±9.2 years in the HBCR group and 58.7±6.1 years in the HCR group. The ANCOVA results indicated that both HBCR and HCR programs were equally effective in reducing anxiety (P=0.001 vs. P=0.015) and stress (P=0.002 vs. P=0.003) among the CABG patients, while only HBCR was effective in alleviating depressive symptoms (P=0.001).
Conclusion: Our results demonstrated the efficacy of HBCR and HCR in diminishing stress and anxiety levels among the CABG patients. However, depression was affected only by HBCR.
Correlates of the “No-Reflow” or “Slow-Flow” Phenomenon in Patients Undergoing Primary Percutaneous Coronary Intervention
Authors: Alidoosti Mohammad , Lotfi Reza , Lotfi-Tokaldany Masoumeh , Nematipour Ebrahim , Salarifar Mojtaba , Poorhosseini Hamidreza , Jalali Arash
Published: November 2018

Background: Despite recent advances in interventional equipment and techniques, the angiographic no-reflow phenomenon occurs in a considerable number of patients undergoing primary percutaneous coronary intervention (PCI). We investigated the clinical, angiographic, preprocedural, and procedural characteristics associated with the no-reflow phenomenon among patients undergoing primary PCI.
Methods: Between March 2008 and April 2013, 530 patients (78.5% male, mean age=58.11±12.39 y) with ST-segment-elevation myocardial-infarction who underwent primary PCI were categorized in 2 groups according to their postprocedural thrombolysis-in-myocardial infarction (TIMI) flow grades:  those with a maximum score of 2 (the no-reflow or slow-flow group) and the ones with a score of 3 (the reflow group). A multivariable logistic regression model was used to find the multiple correlates of the no-reflow phenomenon after PCI.
Results: There were 166 (31.3%) patients in the no-reflow group and 364 (68.7%) in the reflow group. The no-reflow patients were older and had significantly longer target lesion lengths, higher SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) scores, higher infarct-related artery SYNTAX scores, more thrombus burden, and a higher frequency of initial TIMI flow grades of 2 or lower. Our multivariable logistic regression analysis demonstrated that older age, higher numbers of Q waves, not using statin, longer target lesion lengths, higher thrombus grades, and higher infarct-related artery SYNTAX scores remained the independent correlates of increased no-reflow rates after primary PCI (area under the ROC curve=0.784,  95% CI: 0.742–0.826; P<0.001).
Conclusion: Clinical, angiographic, and procedural features of patients undergoing primary PCI may be correlated with the occurrence of the no-reflow phenomenon. The thrombus grade and the infarct-related artery SYNTAX score could be among these factors.
Variaciones en la densidad del oxígeno en el aire y su influencia sobre la salud humana
Authors: Olcina Cantos Jorge , Martín Estévez David
Published: November 2018

Texto resumen.
Dimensión territorial y turística de la ruta norte del Camino de Santiago en el País Vasco: distintas concepciones, valoraciones y propuestas de intervención sobre un fenómeno multifacético
Authors: Porcal Gonzalo María Cruz , Díez Angulo Adrián , Iñiguez De Heredia Josu Junguitu
Published: November 2018

Texto resumen.
Las interfaces urbano-forestales: un nuevo territorio de riesgo en España
Authors: Galiana Martín Luis
Published: November 2018

Texto resumen.
Caudales y variabilidad climática en una cuenca de latitudes medias en Sudamérica: río Aconcagua, Chile Central (33ºS)
Authors: Martínez Carolina , Fernández Alfonso , Rubio Patricio
Published: November 2018

Texto resumen.
Market dynamics and future prospects of the automobile industry in Saudi Arabia
Authors: Rumzi Tausif Mohammad , Imdadul Haque Mohammad
Published: November 2018

As the Kingdom of Saudi Arabia focuses on Vision 2030, there is an immediate need to establish some big manufacturing industries to create jobs and to generate revenue from non-oil sectors. Automobile is one such sector where demand is very high in the Kingdom. Local manufacturing can create a lot of jobs and revenue. This study tries to analyze the scope of automobile sector in the Kingdom. The objective here is to identify the functional value of cars, which can be useful for potential automobile manufacturers. A sample of population is asked about their satisfaction from cars based on five broad factors, namely safety, comfort, aesthetic, instrumentation and engine, through a recent primary survey conducted in 2018. Using structural equation modeling, the study finds that consumers in the Kingdom give maximum importance to the engine of the car. This finding would be helpful for designing the features of a local brand as per the preferences of the local market. Market dynamics indicates a strong consumer base. Future prospects are also promising, as there is strong domestic demand. This can be tapped if production is localized, leading to a development of an entire new manufacturing sector. Finally, the study discusses some feasible options for automobile manufacturing in the Kingdom.
Synthesis of Novel Hybrid Scaffolds of Pyran Chalcone Derivatives Bearing Indole and Pyrrole Rings
Authors: Srikrishna Devulapally , Dubey Pramod Kumar
Published: November 2018

A series of novel hydroxy-pyran–chalcone hybrid compounds 4(a-b), 5(a-f), 7(a-b) & 8(a-f) has been synthesized by employing simple methods in various approaches through convergent synthetic strategies. 4-hydroxy-3-acetylcoumarin and 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one have been used as starting materials and were condensed with indole aldehyde, pyrrole aldehydes independently to give the corresponding chalcones. To further explore, alkylation studies have been carried out on the synthesized hybrid chalcones. The synthesized compounds were established on the basis of IR, HRMS, 1HNMR and 13CNMR spectral data.
Nano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols
Authors: Gavhane Dinesh S. , Sarkate Aniket P. , Karnik Kshipra S. , Jagtap Shritesh D. , Ansari Sajed H. , Izankar Ashwini V. , Narula Ishudeep K. , Jambhorkar Vaishnavi S. , Rajhans Aishwarya P.
Published: November 2018

A proficient, microwave mediated methodology using CuFe2O4 nanoparticle as the catalyst
for S-arylation of substituted benzene boronic acids with thiophenol has been developed. In this method,
the substituted thioethers were easily obtained through a C-S bond formation using microwave irradiation
technique as well as conventional heating in the presence of CuFe2O4 nanoparticles with
modest to excellent yields with the less reaction time. The ligand free microwave technique helped in
the preparation of substituted thioethers in measurable amount within 10 mins. The same results were
obtained with conventional heating in 12h. The reported method is economically efficient and an alternative
to the initial existing method for the preparation of substituted thioethers.
Spatiotemporal Statistical Shape Model for Temporal Shape Change Analysis of Adult Brain
Authors: Binte Alam Saadia , Nii Manabu , Shimizu Akinobu , Kobashi Syoji
Published: November 2018

Background:

This study presents a novel method of constructing a spatiotemporal statistical
shape model (st-SSM) for adult brain. St-SSM is an extension of statistical shape model
(SSM) in the temporal domain which will represent the statistical variability of shape as well as the
temporal change of statistical variance with respect to time.

Aims:

Expectation-Maximization (EM) based weighted principal component analysis (WPCA) using
a temporal weight function is applied where the eigenvalues of each data are estimated by Estep
using temporal eigenvectors, and M-step updates Eigenvectors in order to maximize the variance.
Both E and M-step are iterated until updating vectors reaches the convergence point. A
weight parameter for each subject is allocated in accordance with the subject’s age to calculate the
weighted variance. A Gaussian function is utilized to define the weight function. The center of the
function is a time point while the variance is a predefined parameter.

Methods:

The proposed method constructs adult brain st-SSM by changing the time point between
minimum to maximum age range with a small interval. Here, the eigenvectors changes with aging.
The feature vector of representing adult brain shape is extracted through a level set algorithm. To
validate the method, this study employed 103 adult subjects (age: 22 to 93 y.o. with Mean ± SD =
59.32±16.89) from OASIS database. st-SSM was constructed for time point 40 to 90 with a step of 2.

Results:

We calculated the temporal deformation change between two-time points and evaluated
the corresponding difference to investigate the influence of analysis parameter. An application of
the proposed model is also introduced which involves Alzheimer’s disease (AD) identification utilizing
support vector machine.

Conclusion:

In this study, st-SSM based adult brain shape feature extraction and classification
techniques are introduced to classify between normal and AD subject as an application.
Risk Factors for Postembolization Syndrome After Transcatheter Arterial Chemoembolization
Authors: Arslan Muhammet , Degirmencioglu Serkan
Published: November 2018

Background: Transarterial Chemoembolization (TACE) is a minimally invasive treatment
in managing unresectable liver primary neoplasms or liver metastases. Postembolization Syndrome
(PES) is the most common adverse effect after TACE procedures.

Objective: We investigate the risk factors for the development of PES after TACE therapy in patients
with primary or metastatic liver tumors.

Methods:

In a retrospective analysis of 163 patients who underwent TACE between 01/01/2012
and 31/01/2018, patients that were given medication due to pain, fever, nausea or vomiting were
evaluated and noted with PES. Analyses were made to evaluate factors such as age, gender, chemotherapy
agent and dose, tumor size, tumor type, a particle used for embolization, multiple tumor
treatments and selective application of the procedure, which may lead to PES after TACE.

Results:

In a total of 316 patients, PES was observed at a rate of 55 percent after TACE. Tumor
size, number of tumors treated and adopting super selective fashion in the procedure were found to
be related to the development of PES. No relationship was found between age, gender, presence of
ascites, tumor type, size of embolic agent and drug type and the development of PES.

Conclusion:

A treated tumor measuring >5 cm, treating more than one tumor, and the failure to
perform the procedure in a super selective fashion increase the risk of PES development after
TACE.
Immunomodulatory Activity of Punarnavine Alkaloid from Boerhaavia diffusa
Authors: Aher Vaibhav D. , Chattopadhyay Pronobesh , Patra Arjun
Published: November 2018

Background:

Immunomodulators could alter the activity of the immune system. Most of the
synthetic chemotherapeutic agents are immune suppressants and produce side effects.
Immunomodulators derived from plants are used as general adaptogens and immune strengtheners
without undesired effects.

Methods:

Present study established the mode of immunostimulatory action of punarnavine alkaloid
(PA) isolated from Boerhaavia diffusa Linn. root by examining various parameters. PA was separated
from B. diffusa and its acute toxicity was studied by up-down regulation method. Immunomodulatory
activity of PA was determined in Albino mice by observing its effect on organ weight (liver, spleen,
thymus and kidney), expression of cytokines, bone marrow cellularity and alpha-esterase positive cells.
Plaque Forming Assay (PFA), Delayed Type Hypersensitivity (DTH), and phagocytosis activity were
also carried out to support the effect of PA. PA did not exhibit any toxic effect in mice.

Results:

In DTH study, the foot pad thickness due to influx of mononuclear cells at the site of inoculation
was distinctly increased in PA treated mice. PA enhanced the phagocytic activity of the polymorphonuclear
cells by increasing the engulfment of the Candida cells thereby stimulating a non-specific
immune response. PFA confirmed that PA treatment could elevate the humoral immune response due to
the synthesis of antibody which in turn is responsible for the enhancement of macrophages and Blymphocyte
subsets. The significant increase in the number of α-esterase positive cells and bone marrow
cellularity due to immunomodulatory effect indicated the proliferation of stem cells. Different organ
weight was also markedly improved by PA treatment compared to SRBC sensitized group. Further, in
real time PCR studies treatment of PA significantly increased IL- 7, IL- 10, IL-12a and IL-12b mRNA
gene expression.

Conclusion:

From the above findings it can be concluded that PA could be developed as a potent immunomodulatory
agent.
Dysfunctional Mechanism of Liver Cancer Mediated by Transcription Factor and Non-coding RNA
Authors: Zeng Wei , Wang Fang , Ma Yu , Liang Xianchun , Chen Ping
Published: November 2018

Background:

There have been numerous experiments and studies on liver cancer by biomedical scientists, while no comprehensive and systematic exploration has yet been conducted. Therefore, this study aimed to systematically dissect the transcriptional and non-coding RNAmediated mechanisms of liver cancer dysfunction.

Method:

At first, we collected 974 liver cancer associated genes from the Online Mendelian Inheritance in Man (OMIM). Afterwards, their interactors were recruited from STRING database so as to identify 18 co-expression modules in liver cancer patient expression profile. Crosstalk analysis showed the interactive relationship between these modules. In addition, core drivers for modules were identified, including 111 transcription factors (STAT3, JUN and NFKB1, etc.) and 1492 ncRNAs (FENDRR and miR-340-5p, etc.).

Results:

In view of the results of enrichment, we found that these core drivers were significantly involved in Notch signaling, Wnt / β-catenin pathways, cell proliferation, apoptosis-related functions and pathways, suggesting they can affect the development of liver cancer. Furthermore, a global effect on bio-network associated with liver cancer has been integrated from the ncRNA and TF pivot network, module crosstalk network, module-function/pathways network. It involves various development and progression of cancer.

Conclusion:

Overall, our analysis further suggests that comprehensive network analysis will help us to not only understand in depth the molecular mechanisms, but also reveal the influence of related gene dysfunctional modules on the occurrence and progression of liver cancer. It provides a valuable reference for the design of liver cancer diagnosis and treatment.
Analysis of Single-Cell RNA-seq Data by Clustering Approaches
Authors: Zhu Xiaoshu , Li Hong-Dong , Guo Lilu , Wu Fang-Xiang , Wang Jianxin
Published: November 2018

Background:

The recently developed single-cell RNA sequencing (scRNA-seq) has
attracted a great amount of attention due to its capability to interrogate expression of individual
cells, which is superior to traditional bulk cell sequencing that can only measure mean gene
expression of a population of cells. scRNA-seq has been successfully applied in finding new cell
subtypes. New computational challenges exist in the analysis of scRNA-seq data.

Objective:

We provide an overview of the features of different similarity calculation and clustering
methods, in order to facilitate users to select methods that are suitable for their scRNA-seq. We
would also like to show that feature selection methods are important to improve clustering
performance.

Results:

We first described similarity measurement methods, followed by reviewing some new
clustering methods, as well as their algorithmic details. This analysis revealed several new
questions, including how to automatically estimate the number of clustering categories, how to
discover novel subpopulation, and how to search for new marker genes by using feature selection
methods.

Conclusion:

Without prior knowledge about the number of cell types, clustering or semisupervised
learning methods are important tools for exploratory analysis of scRNA-seq data.
Recruitment Rates, Natal and Breeding Dispersal of Montagu’s Harriers (Circus Pygargus) by Means of Microsatellite Analysis
Authors: Janowski Susann , Pürckhauer Claudia , Krüger Ralf , Tietze Dieter Thomas , Wink Michael
Published: November 2018

Introduction:

Adult philopatry as well as juvenile dispersal and recruitment rates are key factors for population development. We investigated these questions for the first time in an increasing German population of Montagu’s harrier in Frankonia using microsatellite markers.

Methods:

By means of 16 loci, we genotyped 2265 samples from juvenile and adult female Montagu’s harriers. Parentage and identity tests were used to reconstruct life histories of birds for a 10 year period. Most of the birds were breeding in one or two years. The longest life history was eight years.

Results:

Adult philopatry was quite high and differed significantly between sexes. We found 73.5% of females to breed < 5 km around the previous nest site (80.4% < 10 km, median nesting distance 2.1 km). All investigated males (n=18) were breeding in a distance of < 5 km (median nesting distance 1.3 km) to the previous nest. Juveniles showed a low recruitment rate (females: 2.9%, males: 4.9%, together 4%). Median natal dispersal distance was 19.1 km for females and 12.3 km for males. We found 29.4% of females and 41.2% of males to be philopatric, as the distance between hatching and first breeding site was < 10 km. Philopatry results mostly agree with data from other European countries.

Discussion:

Due to strict marker and data selection we received high quality life histories of Montagu’s harriers, which demonstrate that microsatellite analyses are valuable tools in ornithology.

Conclusion:

Nevertheless, comparison of philopatry and recruitment rates depend directly on the scale used and investigation method and therefore remain a challenge.
Pharmacological Evaluation of Abietane Diterpenoids from Plectranthus bishopianus as Potent Antibacterial, Antioxidant and Their Cytotoxic Agents
Authors: Vinodh Guvvala , Naveen Polkam , Venkatesan Chidambaram Subramanian , Rajitha Galla , Shree Anireddy Jaya
Published: November 2018

Background:

Lamiaceae is one of the large families that occur worldwide and has species
that are adaptable to almost all habitats and altitudes. Plectranthus is an important genus of Lamiaceae,
recognized globally as an ornamental as well as a medicinal herb with good economic interest.
The Plectranthus species possess antiseptic, vermicidal and purgative activities.

Objective:

The isolated compounds (1-3) from Plectranthus bishopianus were tested for their preliminary
pharmacological evaluation for antibacterial, antioxidant and cytotoxic activities.

Materials and Methods:

The Plectranthus bishopianus leaves were collected from the Western
Ghats of India. Extractions followed by isolation of the three compounds and structures were identified
by NMR, HRMS.

Results:

The isolated compounds, 6,7-dehydroroyleanone (1), 6β-hydroxy-7α-methoxyroyleanone
(2) and 6β, 7α-dihyroxyroyleanone (3) showed good antioxidant activity by DPPH method. The
results of the cytotoxicity evaluation of the compounds (1-3) displayed excellent activity against
MCF-7 cell line with IC50 values at 3.8 µg/mL, 3.85 µg/mL and 3.7 µg/mL respectively, which is
more potent than the reference standard cisplatin.

Conclusion:

The structures of isolated compounds were confirmed by NMR, LC-HRMS and further
pharmacological evaluation was accomplished. In addition, the isolates (1-3) were subjected to
insilico molecular properties prediction by employing Molinspiration software for calculating their
oral bioavailability and predicted to possess excellent oral bioavailability.
Antibacterial, Antifungal and Anti-tubercular Activities of Chloroform Fraction of the Leaf Extract of Irvingia Gabonensis (African Bush Mango)
Authors: Olanrewaju Ifedolapo O. , Mordi Raphael C. , Echeme JohnBull O.
Published: November 2018

Background:

The prevalence of anti-drug resistance by disease causing microorganisms
has necessitated the search for alternative sources of drugs for the treatment of the ailments caused
by these microorganisms. This study examines the biological properties of extracts from the leaves
of Irvingia gabonensis (bush mango).

Objective:

The objective of this study is to determine the anti-microbial activity of chloroform
fraction of the leaf extract and compare it with that of clinical reference.

Methods:

Antimicrobial activity of the chloroform fraction of the leaf extract of Irvingia gabonensis
was evaluated against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella
dysenteriae, Salmonella typhi, Klebsiella pneumonia, Salmonella paratyphi, Candida albicans
and Trichophyton rubrum by using the agar well diffusion method and Mycobacterium tuberculosis
using agar proportion method on Lowenstein–Jensen medium. Preliminary phytochemical
screening of the chloroform leaf fraction was done using qualitative standard methods.

Results:

This showed the presence of saponins, flavonoids, tannins, coumarin, phenol and alkaloids.
Organisms were susceptible to chloroform fraction at different concentrations. The lowest
MIC value obtained was 0.625mg/mL for S. aureus and S. typhi. While, five out of seven mycobacterial
strains that were used, were susceptible.

Conclusion:

The antimicrobial activity is a result of the phytochemicals present in leaf. Therefore,
we conclude that Irvingia gabonensis leaves can be used in the development of new pharmaceuticals
research activities such as drug production.
Word and Character Information Aware Neural Model for Emotional Analysis
Authors: Beseiso Majdi
Published: November 2018

Background:

Social media texts are often highly unstructured in accordance with the
presence of hashtags, emojis and URLs occurring in abundance. Thus, a sentiment or emotion analysis
on these kinds of texts becomes very difficult. The difficulty increases even more when such
texts are in local languages like Arabic.

Methods:

This work utilizes novel deep learning architectures in the form of character-level Convolutional
Neural Network (CNN) module and the word-level Recurrent Neural Network (RNN) module
to produce a hybrid architecture that makes use of the character level analysis and the word level
analysis to obtain state-of-the-art results on a totally new Arabic Emotions dataset.

Results:

The proposed method works the best among the traditional bag-of-words and Term Frequency
and Inverse Document Frequency methods for emotion analysis. It also outperforms the
state-of-the-art deep learning methods which are known to perform very well in an English corpus.

Conclusion:

The proposed deep end-to-end architecture utilizes the character level information from
a text through the Character CNN Module and the word level information from a text through the
Word-Level RNN Module.
Optimal Privacy Preserving Technique Over Big Data Analytics Using Oppositional Fruit Fly Algorithm
Authors: Kiran Ajmeera , Devara Vasumathi
Published: November 2018

Background:

Big data analytics is the process of utilizing a collection of data accompanied
on the internet to store and retrieve anywhere and at any time. Big data is not simply a data but
it involves the data generated by variety of gadgets or devices or applications.

Objective:

When massive volume of data is stored, there is a possibility for malevolent attacks on
the searching data are stored in the server because of under privileged privacy preserving approaches.
These traditional methods result in many drawbacks due to various attacks on sensitive information.
Hence, to enhance the privacy preserving for sensitive information stored in the database,
the proposed method makes use of efficient methods.

Methods:

In this manuscript, an optimal privacy preserving over big data using Hadoop and mapreduce
framework is proposed. Initially, the input data is grouped by modified fuzzy c means clustering
algorithm. Then we are performing a map reduce framework. And then the clustered data is
fed to the mapper; in mapper the privacy of input data is done by convolution process. To validate
the privacy of input data the recommended technique utilizes the optimal artificial neural network.
Here, oppositional fruit fly algorithm is used to enhancing the neural networks.

Results:

The routine of the suggested system is assessed by means of clustering accuracy, error value,
memory, and time. The experimentation is performed by KDD dataset.

Conclusion:

A result shows that our proposed system has maximum accuracy and attains the effective
convolution process to improve privacy preserving.
Optimized Model for Cervical Cancer Detection Using Binary Cuckoo Search
Authors: Jain Rachna , Sangwan Saurabh Raj , Bachhety Shivam , Garg Surbhi , Upadhyay Yash
Published: November 2018

Background:

Cervical Cancer is one of the leading causes of deaths among women in India. Accurate and early detection of cancer seems to be a fruitful approach in the diagnosis process. It will be a boon for the medical industry. Prediction of cervical cancer using all the features takes a lot of time and computational resources. Hence, reducing the features and taking only essential features into consideration is an effective solution.

Objective:

The aim of the research is to identify the relevant features in the classification of cancer and optimize the model. Feature selection increases the accuracy percentage of any classifier. The binary cuckoo search optimization algorithm was applied to explore the important features in the attribute list.

Methods:

In our research, the performance of the proposed framework has been verified via instigating it with base classifiers such as Random Forest, kernel SVM, Decision Tree and kNN and then evaluated the results with and without Binary Cuckoo Optimization (BCO). The proposed method involves cuckoo search algorithm for selection of optimal feature split points. Cuckoo Search Optimization is a nature stimulated and breeding process of the cuckoo bird’s algorithm to predict best global solution.

Results:

The results produced only selected features vital for prediction of cancer. In addition, its performance has been paralleled against other factors such as Accuracy, Precision, Recall and Specificity and F-measure.

Conclusion:

The experimental results show that Decision Tree classifier outperforms all other classifiers with an accuracy of 94.7% increased to 97% after Cuckoo Optimization.
Withdrawal Notice: An Improved Collaborative Filtering Method through Content Association
Authors: Sun Runyuan , Ji Ke , Ma Kun , Yuan Dongfeng
Published: November 2018

The article has been withdrawn at the request of the authors and editor of the journal Recent Advances in Computer Science
and Communications.;

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
IDR Privacy Protection Based on Database Digital Watermarking
Authors: Li Yuancheng , Ma Longqiang , Li Xiang
Published: November 2018

Background:

In smart grid, a flexible demand response management mechanism is used
to achieve the purpose of stabilizing the power grid, optimizing the power market, and rationally allocating
resources. There are two types of demand response management in the demand response
management mechanism: Price-based Demand Response (PDR) and Incentive-based Demand Response
(IDR).

Methods:

The paper studied the problem of privacy protection in IDR, and proposed a method based
on database digital watermark to protect user privacy. Segment the time, and then embed watermarks
in the user’s consumption data of each time segment. At the end of each billing period, extract the
watermarks from the data of each segment time, and then send the total consumption data of the user
of this billing period to the power supply company. The power supply company only knows the total
consumption data of the user, the company does not have any information regarding the users consumption
data which can prevent them from snooping the user privacy. The proposed digital watermarking
algorithm is based on K-Means clustering and wavelet transform, the K-Means algorithm is
used to cluster the database tuple data, and then wavelet transform is carried out on the available attribute
values within the clusters, and the watermark is embedded in the transformed attribute values.

Results:

The experimental results show that the proposed method is more robust when the database is
under subset deletion attacks, subset substitution attacks and subset addition attacks. Besides, the
computational cost is very low.

Conclusion:

The proposed digital watermark algorithm can embed the watermarks more decently
and overcome the burden of watermark embedding caused by statistical feature control. Besides, the
proposed method can protect the user privacy better than the other two methods.
KAJIAN BENCANA ANGIN RIBUT DI INDONESIA PERIODE 1990-2011: UPAYA MITIGASI BENCANA
Authors: Nurjani Emilya , Rahayu Arum , Rachmawati Febriyan
Published: November 2018

Tulisan ini bertujuan untuk mengkaji kejadian bencana angin ribut di Indonesia.Data yang digunakan adalah data kejadian angin ribut di Indonesia periode 1990-2011dari BNPB. Data diolah statistik deskriptif dan dilakukan analisis spasial.Pemetaan secaraspasial akan memudahkan dalam menganalisis distribusi dan kecenderungan lokasiterjadinya angin ribut setiap tahunnya dan mengetahui daerah-daerah di Indonesia yangmemiliki kejadian bencana angin ribut tertinggi. Angin ribut banyak terjadi di PulauJawa.Provinsi Jawa Tengah merupakan daerah dengan kejadian angin ribut terbanyak(393 - 490 kejadian), sedangkan Provinsi Bengkulu dan Papua Barat tidak terjadi anginribut (nol kejadian).Jumlah kerusakan bangunan terbanyak akibat angin puting beliungtahun 1990-2011 terjadi di Provinsi Jawa Tengah, sedangkan jumlah korban jiwaterbanyak terjadi di Provinsi Jawa Barat.Upaya mitigasi bencana dapat diutamakan padadaerah-daerah yang rawan akan bencana tersebut. Mitigasi bencana akan mengurangidampak buruk dari bencana angin ribut, sehingga kerugian akan kerusakan dari elementat risk karena bencana angin ribut dapat diminimalisasi besarnya.Kata Kunci : angin ribut, mitigasi bencana, kajian
IDENTIFIKASI PROSES-PROSES GEOMORFOLOGI YANG BERPENGARUH TERHADAP LITIFIKASI ENDAPAN PIROKLASTIK PADA BAGIAN HULU SUNGAI GENDOL PASCA ERUPSI MERAPI TAHUN 2010
Authors: Wacanodan Efrinda Ari Ayuningtyas Dhandhun
Published: November 2018

Letusan Gunungapi Merapi tahun 2010 merupakan letusan yang paling besarselama kurun waktu 100 tahun terakhir. Letusan tersebut mengeluarkan lava dan materialpiroklastik dengan total kurang lebih 140 juta meter kubik. Material tersebut tersebar padaseluruh wilayah disekitar gunungapi. Lokasi penelitian adalah Sungai Gendol, yaitu salahsatu wilayah yang menjadi jalur aliran lava dan material piroklastik letusan Merapi di tahun2010. Material hasil letusan Merapi akan mengalami proses pengendapan menjadi lapisanbatuan volkaniklastik, tetapi dalam prosesnya ada banyak faktor yang mempengaruhiproses litifikasi endapan tersebut. Faktor tersebut adalah proses geomorfologi yangbekerja pada material endapan hasil letusan terutama pada bagian hulu lokasi penelitian.Tujuan dari penelitian ini adalah untuk (a) mengidentifikasi proses-proses geomorfologiyang bekerja pada bagian hulu Sungai Gendol, (b) memetakan proses-prosesgeomorfologi yang terjadi di hulu Sungai Gendol. Metode yang digunakan dalampenelitian ini adalah metode survei lapangan. Adapun tahapan dalam penelitian ini antaralain meliputi tahap analisis laboratorium dan tahap survei lapangan. Hasil penelitianmenunjukkan bahwa Sungai Gendol bagian hulu mengalami proses geomorfologi berupagerakmassa material endapan dan proses geomorfologi antropogenik.Kata Kunci: Proses geomorfologi, litifikasi, endapan piroklastik
STUDI TEMPERATUR UDARA TERKINI DI WILAYAH DI JAWA TENGAH DAN DIY
Authors: Purwantara Suhadi
Published: November 2018

Artikel ini dikembangkan dari penelitiaan dengan judul Studi Revisi Rumus Braakdan Mock tentang Gradien Suhu Udara di Jawa Tengah dan DIY” ini berawal dari hasilperhitungan gradien suhu udara menurut rumus Braak yang sudah tidak sesuai denganfakta lapangan. Banyak wilayah pegunungan yang dulu relatif dingin sekarang sudahtidak dingin seperti dulu lagi. Masyarakat merasa temperatur udara semakin panas. Untukitu dalam penelitian ini bertujuan untuk mengetahui suhu udara di permukaan air laut,perbedaan suhu udara per seratus meter hingga ketinggian 2000an meter, dan selisihhasil perhitungan dengan formula Braak dengan data di wilayah penelitian. Populasidalam penelitian ini ad alah semua udara yang ada di wilayah permukaan bumi di PulauJawa bagian Tengah. Penelitian ini bersifat penelitian kuantitatif berdasarkan hasilpengukuran langsung dan perekaman data sekunder. Penelitian ini menggunakaninstrumen thermometer, dan formulir isian data. Pengumpulan data sekunder diperolehdari instansi-instansi yang terkait dengan masalah dan tujuan penelitian antara lain : datatemperatur. Dalam penelitian ini analisis dilakukan dengan memasukkan hasil pengukuranprimer yang dirata-rata kemudian dimasukkan dalam rumus Braak. Hasil penelitianmenunjukkan perbedaan suhu udara berdasar perbedaan tinggi tempat masih mengikutirumus Braak, hanya suhu udara di permukaan laut yang sering para penelitimenggunakan angka 26,3⁰C, menjadi 28,5⁰C. Temperatur udara berdasarkan datamenunjukkan bahwa terjadi peningkatan yang sangat nyata. Wilayah pantai yangmerupakan wakil permukaan air laut bersuhu udara bulan April Mei 2012 sebesar 28,5⁰C,suhu udara pada 800 m sebesar 24⁰C, dan suhu udara pada ketinggiaan udara 2100meter sebesar 16,25⁰C. Pada ketinggian 800 meter, perbedaan temperatur hasilperhitungan rumus Braak dengan data lapangan hanya 23,62 ˚C dengan 24 ˚C, atau 1,2%,sedangkan di wilayah dengaan ketinggian 2100 meter, perbedaan temperatur hasilperhitungan rumus Braak dengan data lapangan hanya 16,70 ˚C dengan 16,25 ˚C, atau2,1%.Kata kunci: temperature udara, gradien suhu
DIVERSIFIKASI PERDESAAN BERASOSIASI DENGAN INDUSTRI PARIWISATABERPERAN DALAM MEMBENTUK KARAKTER BANGSASTUDI DI KECAMATAN UNGARAN BARAT KABUPATEN SEMARANG
Authors: Su Ritohardoyo Puji Hardati, R. Rijanta,
Published: November 2018

Industri pariwisata merupakan salah satu kegiatan sektor non-pertanian diperdesaan. Keberadaannya menjadi salah satu alternatif sumber lapangan pekerjaan danpendapatan rumah tangga. Industri pariwisata di perdesaan akan mendorong prosesdiversifikasi perdesaan. Tulisan ini bertujuan untuk mengkaji diversifikasi perdesaanberasosiasi dengan industri pariwisata dan peranannya dalam membentuk karakterbangsa. Hasil penelitian menunjukkan bahwa diversifikasi perdesaan yang berasosisasidengan industri pariwisata distribusinya tidak merata ke seluruh wilayah. Desa-desa yangterdeversifikasi sangat kuat terdistribusi secara keruangan pada desa-desa denganaksesibilitas yang tinggi. Keberadaan lokasi wisata menjadi salah satu modal utamadalam mendorong diversifikasi perdesaan berasosiasi dengan industri pariwisata.Pariwisata berperan dalam mengenalkan dan melestarikan kearifan lokal dan berperandalam membentuk karakter bangsa terutama gererasi mudaKata kunci: Diversifikasi Perdesaan, Industri pariwisata.
HYDROGRAPH ANALYSIS FOR SUSTAINABLE KARST AQUIFER PROTECTION AND MANAGEMENT
Authors: Fatchurohman Hendy , Cahyadi Ahmad , Suprayogi Slamet
Published: November 2018

AbstrakKeberadaan mata air karst sangat penting karena dapat berfungsi sebagai sumber air minum. Analisis hidrograf mataair karst merupakan langkah mendasar untuk menilai dan mengetahui kondisi daerah tangkapan air di daerah karst. Kurva resesi dipahami sebagai bagian paling stabil di hidrograf banjir tunggal yang mewakili karakteristik akuifer. Oleh karena itu, analisis kurva resesi digunakan untuk menentukan karakteristik akuifer, termasuk tingkat karstifikasi. Makalah ini difokuskan pada bagaimana menentukan derajat karstifikasi. derajat karstifikasi yang digunakan dalam makalah ini diperkenalkan oleh Malik (2007) yang juga memperhatikan analisis kurva resesi. Metode ini difokuskan pada karakteristik independen sub-rezim pada periode resesi. Kurva resesi adalah masukan utama untuk membuat persamaan recessional yang dikonversi menjadi nilai derajat karstifikasi. Skala kualitatif mulai dari 1 sampai 10 mewakili tingkat karstifikasi. Kedua metode tersebut berlaku umum di Indonesia. Kata kunci: Airtanah, derajat karstifikasi, hidrograf, manajemen