bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential of Ecoenzymes and N2 Nanobubbles on the Growth of Phalaenopsis sp. Orchid at the Acclimatization Stage
Authors: Syafitri Fitria Indah , Rahayu Tintrim , Jayanti Gatra Ervi
Published: February 2024

Growth is a quantitative change during one plant’s life cycle and is irreversible.withaddition An in crease the volume or dry weight of plants or other organs is due to the adding, of new structural elements. Phalaenopsis (moth orchid) is a genus of orchids appeal. The diversity of colors, shapes, and textures, as well as its aroma, make Phalaenopsis orchids one of the charming flowers of Indonesia. Ecoenzyme is a solution of complex organic substances produced from the fermentation of organic residues, sugar, and water. Nanobubbles (NBs) are an example of nanotechnology. NBs have a diameter of 1-100 nm and are nanoscopic gas bubbles in a solution or water that can change the characteristics of water and are stable. This study aims to determine the potential of giving Ecoenzyme and NBs N2 on the growth of Phalaenopsis orchids during the acclimatization stage. This research was conducted from October to December 2022 at the Orchidology and Nursery Laboratory, Islamic University of Malang. This study used an experimental method with a completely randomized design (CRD) with 10 treatments, namely 0 mL/L (control), 1 mL/L Ecoenzyme, 2 mL/L Ecoenzyme, 3 mL/L Ecoenzyme, 4 mL/L Ecoenzyme, 4 combination NBs N2 and Ecoenzymes, and 5 mL NBs N2 with 3 replications, making a total of 30 treatment units. The research parameters included the number of leaves, leaf length, number of roots, root length, plant height, fresh weight, and plant dry weight. The results of this study showed that the treatment of 3 mL/L Ecoenzyme showed potential in increasing the number of leaves by 4 pieces: at the same time the optimal concentration of the combination of Ecoenzyme and NBs was 2 mL/L plus 5 mL NBs N2 in increasing the number of roots by 10 pieces, and the optimal concentration of NBs was 5 mL in increasing the root length by 7.07 cm, plant height by 17.10 cm leaf. length, plant weight by 4.16 g and dry weight by 0.85 g in Phalaenopsis orchids.
Modernização do Regimento Geral da USP frente aos avanços da Universidade
Authors:   Universidade de São Paulo, Cocareli André Ramos , Pacheco Mônica ,   Universidade de São Paulo, Nunes Mirian Megumi Sawada ,   Universidade de São Paulo, Fuzishima Sissi ,   Universidade de São Paulo, Cazarotti Renata Aparecida Terra ,   Universidade de São Paulo, Magro Fernanda Maria Ortega ,   Universidade de São Paulo, Antonio Wagner Paschoal de Andrade ,   Universidade de São Paulo, Reis Renata de Góes Cordeiro Pinheiro Teixeira dos ,   Universidade de São Paulo, Gallottini Marina ,   Universidade de São Paulo, Macedo Odesildo Olímpio de ,   Universidade de São Paulo, Noboa Luan Felipe Novak ,   Universidade de São Paulo, Silva Jurema Lúcia dos Santos ,   Universidade de São Paulo, Lima Priscilla Dantas de ,   Universidade de São Paulo, Desiderio Eliana Cristina Quaresma ,   Universidade de São Paulo, Marinho Edinalva Ferreira ,   Universidade de São Paulo
Published: February 2024

Introdução: Recentemente, ações desenvolvidas pela USP contribuíram para que a universidade atingisse alto padrão de qualidade. As diversas medidas e programas instituídos exigem a modernização dos instrumentos de gestão. O Estatuto e o Regimento Geral são instrumentos que regulamentam a finalidade, estrutura, competências e atribuições dos órgãos da Universidade, possibilitando atender ao princípio da legalidade e promovendo agilidade/transparência à gestão. Objetivo: Incorporar as alterações e emendas realizadas no Estatuto e no Regimento Geral da USP, bem como identificar dispositivos contraditórios, tornaram-se incorretos ou irrelevantes frente às alterações ocorridas durante os anos. Ainda, de acordo com a experiência do grupo, sugerir modificações para aprimorar a aplicação das normas no cotidiano universitário, sobretudo quanto às eleições e ao funcionamento dos órgãos colegiados, além dos concursos da carreira docente. Metodologia: Foi instituído um grupo de trabalho composto por assistentes acadêmicos, um Analista da Procuradoria Geral e três servidores da Secretaria Geral. O RG será revisado por artigos, que receberão as consolidações necessárias e as propostas de modificações que sejam condizentes com a realidade atual da USP. A partir da análise do RG, se necessário, propor adequações no Estatuto, a fim de evitar descompasso entre as normas. Resultados: A revisão está em andamento, com previsão de término para 13.11.2023, quando pretendemos tramitar o novo Regimento nas instâncias competentes da Universidade, até sua aprovação pelo Conselho Universitário, em 2024. Conclusão: O Regimento modernizado, além de ficar mais objetivo, garantirá aos usuários o suprimento efetivo de suas demandas, contribuindo para as boas práticas na Universidade.
Aplicação de uma Avaliação Diagnóstica para Identificação da Percepção de Gestores da Universidade em Relação ao Gerenciamento de Riscos e Controles Internos
Authors:   Universidade Estadual Paulista, Louro Daniel Wayne
Published: February 2024

Introdução: O Grupo Técnico de Gestão de Riscos e Controle Interno da Universidade Estadual Paulista "Júlio de Mesquita Filho" conduziu uma avaliação entre agosto e setembro de 2022 para analisar a percepção dos gestores em relação ao cumprimento dos princípios e diretrizes estabelecidos na Política de Gerenciamento de Riscos e Controles Internos da Unesp. De 693 gestores, 389 responderam ao questionário. Outro objetivo era determinar o nível de maturidade da universidade em relação ao gerenciamento de riscos e controles internos com base nas respostas dos gestores. Objetivo: Demonstrar como foi aplicada uma avaliação visando diagnosticar a atuação da Universidade em relação ao gerenciamento de riscos e controles internos. Metodologia: O questionário tinha 92 questões e abrangeu cinco seções relacionadas a componentes da metodologia COSO-ICIF, cada uma representando aspectos diferentes do controle interno. Os participantes classificaram os controles em uma escala de 1 (mais fraco) a 5 (mais forte). Com base em uma média percentual dos resultados, as questões foram classificadas em níveis de maturidade. Resultados: Após analisadas as respostas, foram elaborados relatórios. Utilizando-se a ferramenta Power BI, foram apresentados também resultados interativos, para uma análise mais aprofundada. Conclusão: A avaliação demonstrou a necessidade de disseminar a cultura de controle na universidade, além de ter auxiliado na identificação de áreas mais sensíveis. Como sugestão de continuidade, propõe-se a coleta de evidências adicionais por meio de entrevistas e análises presenciais em processos e documentos. Isso facilitaria o planejamento de ações, garantindo uma assessoria eficaz nas áreas identificadas como mais críticas.
Do desafio à conquista: estratégias exitosas de envolvimento multiprofissional
Authors:   Universidade Estadual de Campinas, Schweller Mariana Salhab Dall Aqua , Carvalho Luciana Aparecida Costa ,   Universidade Estadual de Campinas, Silva Ana Lucia da ,   Universidade Estadual de Campinas, Gasparotto Ana Paula Devite Cardoso ,   Universidade Estadual de Campinas, Nascimento Andrea Devidis ,   Universidade Estadual de Campinas, Moitinho Ana Carolina Braz ,   Universidade Estadual de Campinas, Stamponi Danilo da Silva ,   Universidade Estadual de Campinas, Ravagnani Juliana Furlan ,   Universidade Estadual de Campinas, Psaltikidis Eliane Molina ,   Universidade Estadual de Campinas, Ratti Ligia dos Santos Roceto ,   Universidade Estadual de Campinas, Urquisa Priscila Silva ,   Universidade Estadual de Campinas, Lima Tiago Cristiano de ,   Universidade Estadual de Campinas, Silva Nilcilene Pinheiro ,   Universidade Estadual de Campinas, Bachur Luís Felipe ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: No dinâmico cenário do Hospital de Clínicas da Unicamp, o Projeto Saúde em Nossas Mãos, realizado entre 2021 e 2023, enfrentou desafios complexos na busca pela excelência nos cuidados de saúde. Focado na redução da densidade de incidência de Infecções Relacionadas à Assistência em Saúde (IRAS) na UTI-Adulto, o projeto destacou a necessidade de engajar a equipe multiprofissional em um propósito comum. Objetivo: Apresentar as estrategias exitosas aplicadas para envolvimento da equipe multiprofissional no projeto. Metodologia: Para alcançar esse objetivo, adotamos uma abordagem multifacetada, implementando estratégias lúdicas, promovendo o envolvimento profissional, valorizando a opinião da equipe e propagando conhecimento. Resultados: Ao monitorar sistematicamente a adesão às práticas preventivas, superamos a meta de 85%, atingindo uma adesão final de 87% aos bundles obrigatórios. Os resultados impressionantes incluíram reduções significativas na incidência de IRAS, refletindo o engajamento e colaboração das diversas categorias profissionais, culminando em impactos notáveis na qualidade e segurança do atendimento. Conclusão: A união de profissionais de diferentes setores foi a chave para o sucesso. A mudança cultural, embora demandasse paciência, persistência e consistência, resultou em uma cultura institucional mais resiliente e adaptável. O projeto não apenas representa uma conquista quantificável, mas semeia as bases para um futuro promissor no cuidado à saúde na instituição.
The characteristics and clinical outcomes of trauma patients transferred by a physician-staffed helicopter emergency medical service in Korea: a retrospective study
Authors: Jang Myung Jin , Choi Woo Sung , Lee Jung Nam , Park Won Bin
Published: February 2024

Purpose: Helicopter transport with medical teams has been proven to be effective, with improvements in patient survival rates. This study compared and analyzed the clinical characteristics and treatment outcomes of trauma patients transported by doctor helicopters according to whether patients were transferred after a clinical evaluation or without a clinical evaluation.Methods: This study retrospectively reviewed data from the Korean Trauma Data Bank of trauma patients who arrived at a regional trauma center through doctor helicopters from January 1, 2014, to December 31, 2022. The patients were divided into two groups: doctor helicopter transport before evaluation (DHTBE) and doctor helicopter transport after evaluation (DHTAE). These groups were compared.Results: The study population included 351 cases. At the time of arrival at the trauma center, the systolic blood pressure was significantly lower in the DHTAE group than in the DHTBE group (P=0.018). The Injury Severity Score was significantly higher in the DHTAE group (P<0.001), and the accident to trauma center arrival time was significantly shorter in the DHTBE group (P<0.001). Mortality did not show a statistically significant between-group difference (P=0.094). Surgical cases in the DHTAE group had a longer time from the accident scene to trauma center arrival (P=0.002). The time from the accident to the operation room or from the accident to angioembolization showed no statistically significant differences.Conclusions: DHTAE was associated with significantly longer transport times to the trauma center, as well as nonstatistically significant trends for delays in receiving surgery and procedures, as well as higher mortality. If severe trauma is suspected, air transport to a trauma center should be requested immediately after a simple screening test (e.g., mechanism of injury, Glasgow Coma Scale, or Focused Assessment with Sonography in Trauma), which may help reduce the time to definitive treatment.
The impact of Covid-19 pandemic on the research portfolio and approval turnaround time at the Kenya Medical Research Institute
Authors: Kebenei Enock Kipchirchir , Cheruiyot Daisy , Msee Gideon Cornel , Nguya James , Kiplagat Timothy K , Bukusi Elizabeth A
Published: February 2024

Background: The Covid-19 pandemic led to an unprecedented impact on many sectors globally including research. We assessed the impact of the Covid-19 pandemic on the research portfolio, and on the approval turnaround time for research protocols submitted to the Scientific and Ethics Review Unit (SERU), at the Kenya Medical Research Institute (KEMRI). Methods: We compared research protocols submitted between October 01, 2019 and March 31, 2020 (Period 1), to those submitted between April 1 and September 30, 2020 (Period 2). A document review tool was used to extract data from the 198 research protocols reviewed and approved over the two periods. Results: In the two periods under review, the single largest percentage of protocols (89/198, 45.4%) involved infectious and parasitic diseases, and the single largest percentage of study designs was cross-sectional (75/198, 38%). Before the pandemic, the median time taken to review KEMRI-linked protocols was 87 days and for non-KEMRI linked protocols it was 121 days. During the pandemic, approval turnaround time dropped for both KEMRI and non-KEMRI protocols to 66 days and 92 days, respectively, due to the streamlined processes at the KEMRI SERU. Conclusion: The research portfolio was minimally affected by the pandemic. The adoption of email submission, and faster-than-usual processing and review protocols during the pandemic reduced the approval turnaround time.
Application of computational fluid dynamics for simulation of stirred bioreactors in Ansys Fluent
Authors: Bondarenko N. A. , Guseva E. V. , Safarov R. R.
Published: February 2024

Stirred bioreactors are widely used in the pharmaceutical industry to produce various active substances for the treatment of cancer, heart and vascular diseases, viral and bacterial infections. Despite the widespread use of bioreactors with a stirrer, the optimization of mixing conditions remains an urgent task. In bioreactors of this type, continuous mixing of cells in a medium with a high rotation speed should be carried out. The manuscript considers an example of the use of computational fluid dynamics to study and model the process of cultivation Escherichia coli bacterial cells in a batch bioreactor (NLF, 30 l.). Computational fluid dynamics was used to analyze the hydrodynamic conditions in a bioreactor with a double Rushton turbine stirrer. To describe the movement of flows and evaluate turbulence in a batch bioreactor, the multiphase Euler model and the k-𝜀 turbulence model, respectively, were used, the built-in Ansys Fluent software package. A geometric model was built with the original dimensions of the bioreactor with an NLF 30 stirrer. Based on the geometric model, a computational grid was created for the working volume of the bioreactor and the optimal parameters for constructing the computational grid were selected. As a result of modeling the hydrodynamic regime, the distribution profiles of the turbulence kinetic energy over the volume of the bioreactor were obtained and the velocities of cell movement were found at different speeds of rotation of the stirrer. The obtained results show the possibility and applicability of the Ansys Fluent software package for calculating the hydrodynamic situation in a bioreactor with a stirrer at different stirring rates and at different cell volume fractions.
Options for freezing semi-finished products from bioactivated wheat in grain bread technology
Authors: Alekhina N. N. , Bakaeva I. A.
Published: February 2024

Currently, studies on the freezing of semi-finished bakery products and finished bakery products, especially from bioactivated wheat grain, are relevant, since these products have a preventive and functional orientation due to their valuable chemical composition. Therefore, at the first stage, the effect of freezing options on the change in temperature and freezing rate of the semi-finished product was studied, at the second - the organoleptic and physic-chemical quality indicators of bread obtained using different freezing options were evaluated, at the third - the cyclograms of the bread preparation process based on frozen semi-finished products from bioactivated wheat were built. The objects of the study were samples of semi-finished products from bioactivated wheat prepared using four options for freezing semi-finished products: dough after kneading, dough blanks after molding, proofing and with a readiness of 70-75 %. These samples were subjected to shock freezing at a temperature of -35 °C until the temperature in the center reached -18 °C. As a result of the research, three periods of the freezing process were established for dough, dough blanks and semi-baked products made of bioactivated wheat grain. The longest was the duration of freezing to -18 °C of semi–finished products of an increased degree of readiness (option № 4), the shortest was when freezing the dough after kneading (option № 1). The best organoleptic and physico-chemical indicators of the quality of finished products were observed in bread samples prepared according to variants № 1 and № 4. Based on the conducted research, the Icebread bread technology was developed and cyclograms were constructed that visually reflect the main stages of its technological process.
Immunomodulating multivitamin complex and its role in antioxidant protection of the body
Authors: Pozdnyakova O. G. , Sergeyeva I. Y. , Kazakova M. A. , Nazimova E. V. , Poznyakovsky V. M.
Published: February 2024

The article presents the results of experimental data on the development of an immunomodulatory multivitamin complex and the establishment of its role in the antioxidant defense of the body. The research objects were recipe ingredients, laboratory and industrial samples of the developed product. We used generally accepted and special methods for assessing the quality and safety of the developed product. The technology includes: preparation of raw materials, preparation of a mixture for encapsulation, encapsulation and sealing of capsules with gelatin, assessment of the quality of the resulting product. The composition of a new multivitamin composition with targeted antioxidant properties is given, mg / 1 capsule: red palm oil - 432; ascorbic acid - 70; ascorbate palmitate - 10; tocopherol acetate, 98% - 15.3 (vitamin E - 15); beta-carotene, 98% - 5.1 (beta - carotene - 0.5); silicon dioxide (carrier) - 17.6; gelatin capsule - 110. Total weight 660 mg. The functional properties of the developed product were assessed. The components of the developed product in the form of a multivitamin complex had a positive effect on the analyzed parameters of the SF-36 test. According to the test results, the general state of health in the group of volunteers after taking the multivitamin complex increased by 17.2%, while in the control group by only 9.5%, in terms of viability by 7.2 and 3.6% in the experimental and control groups respectively. The innovativeness of the new drug lies in the rejection of inert materials and the use as a carrier of a unique composition of red palm oil, rich, along with fat-soluble vitamins, highly active antioxidants - lycopene and coenzyme Q10. The proposed method of encapsulation in a protective gelatin capsule. This provides a fast action - a water-soluble and prolonged effect - of the fat-soluble fraction.
Hemp protein: obtaining and functional and technological properties
Authors: Korneeva O. S. , Vasilenko L. I. , Meshcheryakova O. L. , Berestovoy A. A. , Isuwa M. M.
Published: February 2024

The aim of this work was to determine the structural and functional characteristics of the two main hemp seed proteins, water-soluble albumin and salt-soluble globulin and alkali-soluble glutelin. The extract of 0.1 M CaCl2 protein meal of hemp seeds was subjected to sequential extraction to obtain three fractions: albumin in the aqueous phase and globulin (edestin) and glutelin in the salt phase at pH-9.0. Data on the amino acid composition showed the presence of an increased content of aromatic and hydrophobic residues in the globulin fraction. Gel electrophoresis showed that the albumin fraction had fewer disulfide bonds and therefore a more open (flexible) structure. The analysis of the content of essential amino acids in protein isolate and UV concentrate and its individual fractions was carried out for a general understanding of the ways of their application. The balance of amino acid content in the UV concentrate is close to the “ideal protein” and in the future it is advisable to use it to isolate bioactive peptides. Thus, the results obtained indicate that the processes of mechanical and chemical action on hemp flour provide raw materials with a high protein content, containing all essential amino acids and characterized by a predominant content of the sum of water and salt-soluble fractions. In connection with the identified changes in the properties of the protein obtained by different methods for release from antinutrients in the future, it is planned to pay attention to this issue separately.
Improvement of the technology of cooking culinary products from poultry meat for children's food: a systematic review
Authors: Vasyukova A. T. , Kusova I. U. , Edvars R. A. , Shumilina M. D. , Astashev M. A. , Varlamov I. A.
Published: February 2024

Currently, more and more new technologies are being discovered in the food industry and public catering for the production of culinary products from poultry. This type of raw material is very popular among the population, due to its chemical composition and nutritional value. The study of new approaches to the quality and safety of food products for baby food is also an urgent topic. The purpose of this review is to analyze literature sources on new technologies in the production of culinary products from poultry and methods of ensuring safety and quality for the nutrition of children of various age groups. The presented systematic review includes articles from the Scopus, Rsci and Google Scholar databases, limited by the time period from 2011 to 2023, 24 works of highly rated journals are analyzed and divided into three thematic blocks: general studies of semi-finished poultry products, new technologies in the production of culinary products and the safety of culinary products from poultry for children's nutrition different age categories. In the course of the work carried out, various studies of semi-finished poultry products, the impact of new technological techniques on the quality and consumer properties of culinary products, as well as basic research in the field of baby food safety were considered. As a result, a fairly strong experimental and research base in these areas of public catering has been identified. The data of this review will provide invaluable assistance in the development of culinary products from poultry for baby food of various age categories, as well as in the preparation of food rations and the development of technological processes in educational institutions.
SCADA project for milk evaporation in double-effect evaporators
Authors: Borodulin D. M.
Published: February 2024

Human-machine interface tools remain one of the components of production automation systems. Appearance and functional abilities cannot stand still in the same way as automation, in this regard, one of the important aspects of food production automation is highlighted in this paper – a human-machine interface aimed at improving the operator's workplace. At the dispatcher level of automation, it is necessary to provide for the solution of the entire range of tasks set during the implementation of this project. The objectives of the project are to reduce the time for decision-making by personnel, since the effectiveness of the enterprise partially depends on the speed of the task, notification of hazards and violations, as well as the prevention of emergency and abnormal situations during the evaporation of milk, storage and archiving of data on the course of the process necessary for the preparation of reports used to investigate the causes of any emergency when evaporating milk. The project of the human-machine interface of the milk evaporation process, developed in the TRACE MODE environment, is presented. A feature of TRACE MODE is the technology of a single programming line, that is, the ability to develop all the ACS modules using a single tool. In the developed project of the human-machine interface of the milk evaporation process, it is assumed to use two main operator stations and one backup. Two of them are for operator workstations and a backup one used in emergency situations. The developed project in the TRACE MODE environment makes it possible to improve the workplace of the operator of the vacuum evaporation plant, reduce the time required for response and decision-making by personnel. In addition, the automatic alarm system allows you to reduce the number of defective products, and, accordingly, increase output and reduce the cost of production per unit of raw materials. The developed project fully satisfies the technical task and has been put into production.
Perspectives of computational fluid dynamics methods in the study of membrane processes
Authors: Klyuchnikov A. I. , Ovsyannikov V. Y. , Klyuchnikova D. V. , Davydov A. M.
Published: February 2024

In the mathematical modeling of membrane processes, the study of the structural features of the membranes used and the significant limitation of information in the formal description of their separation properties led to the development of physical models that take into account not only the structural features of real membranes, but also their functioning features. When compiling physical models of membrane processes, it is impossible to objectively carry out a quantitative accounting of most factors due to their great diversity and variability, which distances the mathematical model far from the real process. This is why CFD methods reliably and efficiently perform calculations for all physical models and types, including steady or transient flow, incompressible or compressible flow (from small subsonic to hypersonic), laminar or turbulent flow simulations, Newtonian or non-Newtonian fluids, ideal or real gas . The authors analyzed the possibility of using CFD to calculate the hydrodynamics of flows in a membrane bioreactor based on hollow fibers. Safarov R.R. etc., an electronic geometric model of the installation was built, mesh geometry with different densities was selected to optimize the calculation time and solution accuracy for a specific case, the kinetic dependence of cell growth was calculated, the flow rates of the nutrient medium into the intrafiber and interfiber spaces of the bioreactor were determined, and the hydrodynamic conditions were analyzed. All of the above confirms the prospects for using CFD methods for modeling membrane processes complicated by culturing cells on the surface of membranes.
Mechanical activation of aqueous solutions as a way to improve mixing and structure formation in dispersed systems
Authors: Ivanov V. V. , Rudnev S. D. , Borodulin D. M. , Krikun A. I.
Published: February 2024

The process of dough preparation is one of the most complex in bread production technology. Stirring of flour with liquid components (water, aqueous solutions) is a complex process of surface interaction associated with overcoming the surface energy at the interface between phases. The intensity of formation of a homogeneous mixture of flour and liquid components, subsequently transformed into dough, determines its structural and mechanical properties. The aim of the work is theoretical substantiation and experimental confirmation of the influence of preliminary mechanical treatment of liquid components on the process of dough mixing and structure formation of water disperse system. Theoretical analysis of the process of adhesive interaction of bulk material with liquid has been carried out. It is shown that the surface energy at the boundary of interaction with phases should be reduced. It is experimentally established that mechanical action on water and aqueous solutions reduces surface tension by 20-30 %. It is established that at mixing of flour and liquid components of dough the preliminary mechanical treatment gives the effect of improvement of wetting, increase of elasticity and reduction of time of structure formation in dough. The specific power during kneading is reduced by 15-20 %. With the help of rheometry means ("Rheotest", Structurometer ST 2, conical Rebinder plastometer) improvement of structural and mechanical properties of the dough is shown: increase of ultimate shear stress by 20-25 %, decrease of adhesion by 30-40 %, increase of elastic properties after kneading up to 10 %, increase of water-binding capacity. The studies were carried out on laboratory equipment and in production conditions at the enterprises of JSC "Kemerovokhleb".
3D-Printed Model in Preoperative Planning of Sciatic Nerve Decompression Because of Heterotopic Ossification
Authors: Lucas Sarah L. , Gallagher Brian P. , Mullinix Kenneth P. , Brumback Robert J. , Cunningham Bryan W.
Published: February 2024

Case:

A 31-year-old patient presented with an encapsulated sciatic nerve secondary to extensive hip heterotopic ossification (HO), which prevented visualization of a safe osteotomy site to avoid nerve damage. The 3D-printed model demonstrated an easily identifiable osseous reference point along the inferior aspect of the heterotopic mass, allowing for a vertical osteotomy to be safely performed.

Conclusion:

HO is associated with loss of normal anatomic topography. The current case report illustrates the use of a 3D-printed model to identify pertinent anatomic landmarks required for safe decompression of an encapsulated sciatic nerve within the anatomic region of the hip.
Otoritas Bawaslu & Komisi ASN Dalam Penindakan Netralitas Aparatur Sipil Negara
Authors: Suri Muhammad
Published: February 2024

Pemilu salah satu pilar negara demokrasi, sarana kedaulatan rakyat untuk memilih wakil-wakilnya (pemimpin) di legislatif dan eksekutif (DPR, DPD, DPRD (Legislatif) dan Presiden, Wakil Presiden (Eksekutif)), yang dilaksanakan secara demokratis, LUBER dan JURDIL. berlandaskan Pancasila dan Undang-Undang Dasar Negara Republik Indonesia. Penyelenggaraan pemilu LUBER dan JURDIL memerlukan kontribusi banyak pihak khususnya Pengawas Pemilu sebagai Badan Pengawas Pemilu. Untuk mewujudkan pemilu yang demokratis, LUBER dan JURDIL yang menghapuskan pelanggaran bahkan kecurangan di dalamnya masih jauh dari harapan, karena hingga diselenggarakannya pemilu tahun 2019 masih terlihat banyak ditemukan pelanggaran. Salah satunya adalah pelanggaran Netralitas ASN. Merujuk pada UU Pemilu Nomor 7 Tahun 2017, kewenangan pengawasan penyelenggaraan pemilu menjadi tanggung jawab Pengawas Pemilu, jika dibandingkan dengan UU Aparatur Sipil Negara (ASN) Nomor 5 Tahun 2014 disebutkan: terkait dengan ASN , kewenangan pengawasan dilaksanakan oleh KASN. Di sinilah tantangannya untuk mencari jawaban mengenai bagaimana kewenangan dan kedudukan Bawaslu sebagai Pengawas Pemilu dan KASN sebagai ASN Pengawas? dalam menindak pelanggaran Netralitas ASN dalam Pemilu. Permasalahan tersebut ditinjau dalam perspektif normatif sesuai peraturan perundang-undangan yang mengaturnya.
Peranan Harmonisasi Hubungan Kerja Sebagai Manifestasi Work Life Balance Terhadap Karyawan di Indonesia
Authors: Hasyim Ahmad , Najicha Fatma Ulfatun
Published: February 2024

Penelitian terkait Work Life Balance semakin bertambah dan menunjukkan yakni karyawan berstatus buruk pada Work Life Balancenya, salah satu faktor yang mempengaruhinya adalah tidak terciptanya keharmonisan hubungan kerja. Oleh karenanya, tujuan dari penelitian ini yaitu ingin mengetahui bagaimana cara mewujudkan harmonisasi hubungan kerja antara karyawan dengan pengusaha, seberapa pentingnya Work Life Balance diperlukan karyawan dan apakah terlaksananya harmonisasi hubungan kerja merupakan cikal bakal yang bersifat mutlak untuk terciptanya Work Life Balance pada karyawan di Indonesia. Penulis menggunakan metode penelitian studi literatur kepustakaan. Penulis membatasi ruang lingkup permasalahan sebatas pada bagaimana peranan atau fungsi harmonisasi hubungan kerja di dunia kerja secara garis besar yang terjadi di Indonesia. Penelitian ini menunjukkan bahwa harmonisasi hubungan kerja dapat ditempuh oleh kedua belah pihak atas kesepakatan, maupun dengan upaya lain yakni campur tangan pemerintah, sebabnya perwujudan harmonisasi hubungan kerja merupakan sustainable process yang membutuhkan rasa tanggung jawab dan komitmen semua pihak. Implementasi nyata tindakan karyawan, pengusaha dan pemerintah untuk menciptakan harmonisasi berpotensi besar tercapainya Work Life Balance. Walaupun harmonisasi hubungan akan menciptakan ekosistem dunia kerja yang sehat dan positif, tidak selalu mutlak tercapainya Work Life Balance. Menuju target Work Life Balance terdapat faktor lain yang mempengaruhinya, seperti penetapan kebijakan perusahaan dan kebutuhan personal karyawan.
Perbuatan Melawan Hukum Dalam Kegiatan Jual-Beli E-Commerce Berdasarkan Hukum Perdata
Authors: Mulya Ilham Indra
Published: February 2024

Melalui internet, transaksi perdagangan dapat dilakukan secara langsung atau tidak langsung. Hal ini telah mengubah pola perdagangan tradisional menjadi sistem perdagangan yang lebih modern, yang dikenal sebagai Electronic Commerce. E-commerce merupakan aktivitas perdagangan antara pembeli dan penjual yang dilakukan melalui media internet. Namun, sering terjadi juga tindakan-tindakan perbuatan melawan hukum dalam aktivitas jual beli secara online ini. Tujuan penelitian ini untuk mengetahui Perbuatan Melawan Hukum dalam E-commerce berdasarkan Hukum Perdata dan akibat Perbuatan Melawan Hukum dalam perjanjian E-commerce berdasarkan Hukum Perdata. Metode yang digunakan yaitu metode penelitian yuridis normatif. Yuridis mengacu pada penggunaan norma-norma hukum sebagai dasar untuk menyelidiki dan menganalisis peraturan hukum yang berlaku saat ini. Sementara itu, pendekatan normatif melibatkan penelaahan terhadap produk-produk hukum seperti peraturan perundang-undangan, serta pengamatan terhadap realitas sosial yang berkaitan dengan fokus penelitian ini.
Structural assessment of sewer pump stations using a novel photonics-based sensor system
Authors: Fabian Matthias , Scott Richard , Bandyopadhyay Sankhyabrata , Sun Tong , Grattan Kenneth TV , Bustamante Heriberto , Thurner Michael , Llave Raymond , Coiro Enrico , Win Mason , Hearfield Jeremy
Published: February 2024

This paper reports the outcome of the research jointly developed and implemented by Sydney Water and City, University of London (City) to create innovative sensing solutions to long term monitoring of wastewater pump stations (PS) which form part of a network owned and operated by Sydney Water (SW). This has been achieved through recognising the potential of photonic devices for use in this environment and thus designing, fabricating and installing innovative optical fibre sensors, (achieving a strain resolution as low as ~1 microstrain), in two representative pump stations chosen by SW (and designated PS072 and PS001). This innovative sensor system has been complemented by conventional cover meter inspection for reinforcement identification. Being sensitive to the structural differences between the two sites chosen, the scientific rationale behind the sensor design, including the sensor positioning, the number of sensors installed, and the types of sensors required has been justified in detail in this paper. This contextualises the sensor data analysis and the key information extracted from the sensor systems designed and installed, thereby allowing better diagnosis of their respective structural operational conditions. Through this type of synergy of sensor data and structural integrity assessment, the key achievements of the work have been to create not just a continuous data-stream but allow accurate assessment of strain and vibration conditions of the structure in both time and position, through real time in situ monitoring and thus to warn of the potential for structural failure and collapse – the prime objective of the work.
WITHDRAWN: Effectiveness of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Video-Assisted Thoracoscopic Lobectomy: A Randomized Controlled Trial
Authors: He Na , Shi Haixia , Hu Yajuan , Uribe Alberto , Mu Xinhua , Song Fei , Yu Jianshe
Published: February 2024

23, February, 2024. Research Square has withdrawn this preprint
as concerns have been raised (https://pubpeer.com/publications/8DFB6F002B66C99339E8A9696B3310) about the alignment between this study and another by Shi et al. (2020) "Dexmedetomidine improves early postoperative neurocognitive disorder in elderly male patients undergoing thoracoscopic lobectomy". Experimental and Therapeutic Medicine, 20, 3868-3877 (https://doi.org/10.3892/etm.2020.9113). Despite both studies citing the same clinical trial registration, they detail divergent research protocols and outcomes. Due to these significant discrepancies with the information registered for the trial, we have opted to withdraw the paper, and this preprint should not be cited as these important issues need to be clarified in a revised publication.
Novel approach to predicting the ultimate bearing capacity of footings located on soft soil improved by DCM columns using Gaussian process regression models – A practical example
Authors: Dehghanbanadaki Ali , Ahmad Kamarudin , Rashid Ahmad Safuan A. , Yunus Nor Zurairahetty Mohd
Published: February 2024

The use of deep cement mixing (DCM) columns is an effective and affordable technique for ground stabilization. However, designing this method can be complex due to uncertainties in the geotechnical properties of the soil and DCM columns, area improvement ratio, column arrangement, and required cement content. This study aimed to address this issue by using Gaussian process regression (GPR) models to estimate the ultimate bearing capacity (UBC) of soft soil improved with DCM columns.To create and train the GPR models, the study utilized a database of 46 physical modeling tests under end-bearing and floating conditions. The researchers used different kernel functions, including rational quadratic, squared exponential, Matern 5/2, and exponential, for the GPR models. The models were then optimized through Bayesian optimization and compared to other predictive techniques such as multilayer perceptron (MLP), radial basis function (RBF), and neuro-fuzzy inference systems (ANFIS) using test data.As a case study, the researchers evaluated a decision-making model for designing the geotechnical properties of DCM columns. The results showed that the optimized GPR model's accuracy in terms of performance indices was satisfactory for both end-bearing and floating DCM column conditions. The optimized GPR model outperformed MLP, RBF, and ANFIS performance indices using test data. Overall, the study demonstrated that optimized GPR models are a promising method for early prediction of stabilized ground UBC.
Evaluating Crown Scorch Predictions From A Computational Fluid Dynamics Wildland Fire Simulator
Authors: Atchley Adam , Hoffman Chad M. , Bonner Sophie R. , Ritter Scott M. , O’Brien Joseph , Linn Rodman R.
Published: February 2024

Background Crown scorch – the heating of live leaves, needles, and buds in the vegetative canopy to lethal temperatures – is one of the most common fire effects shaping post-fire canopies. Despite the ability of computational fluid dynamic models to finely resolve fire activity and buoyant plume dynamics including heterogenous 3D distributions of forest canopy heating, these models have had only limited use in simulating fire effects and have not been used to evaluate crown scorch. Here, we demonstrate a method of evaluating crown scorch using a computational fluid dynamics model, FIRETEC, and validate this approach by mimicking the experiments that were used to develop Van Wagner’s 1973 crown scorch model.
Results The average scorch height prediction from FIRETEC compares well with the empirical model derived by Van Wagner, which is the most widely used empirical model for crown scorch. We further find that the 3D buoyant plume dynamics from a steady and homogeneous idealized heat source on the ground results in a spatially heterogenous crown scorch pattern reflecting complex heating dynamics that are best represented by percent scorch rather than height of scorch.
Conclusions The ability of the computational fluid dynamics model to capture variation in crown scorch due to 3D buoyant plume dynamics provides direct links between forest structure, fire behavior, and fire effects that can be used by forest managers and researchers to better understand how fires result in crown damage under various environmental and management scenarios.
Polypyrrole-coated agricultural waste loofah for efficient Cr(VI) adsorption and in-situ detoxification from water
Authors: Cao Fengming , Zu Peng , Zhang Ling
Published: February 2024

The polypyrrole modified loofah (PPy-Loof), a novel adsorbent, was prepared simply by in-situ oxidative polymerization of pyrrole onto loofah for effective removal of hexavalent chromium (Cr(VI)) from water. The preparation process of PPy-Loof was investigated, and the structure of prepared PPy-Loof was characterized by SEM-EDS, FT-IR, XRD, and XPS analysis. Batch experiments (the effect of temperature, initial Cr(VI) concentration, PPy-Loof dosage, and coexisting ions) were designed to investigate the adsorption. The Cr(VI) adsorption behaviors of PPy-Loof were analyzed by the isothermal models (Langmuir, Freundlich and Temkin), the kinetic models (Pseudo first-order kinetic, Pseudo second-order kinetic and Intra-particle diffusion models), and adsorption thermodynamics (Gibbs free energy change (ΔG0), entropy change (ΔS0), enthalpy change (ΔH0) and activation energy (Ea)). The Cr(VI) removal mechanism of PPy-Loof was further discussed by studying the influence of the initial pH in the solution, the pH changes of the solution during the process, the analysis of XPS, and the validation of the exchanged Cl− during the Cr(VI) removal. The results indicated PPy-Loof could not only effectively removed Cr(VI) from water, but also achieved in-situ detoxification of Cr(VI) by reduction to Cr(III). Adsorption progress conformed to the Langmuir isotherm and pseudo-second-order model, indicating the chemical and monolayer adsorption. ∆H0 > 0, ∆S0 > 0, ∆G0 < 0, indicated the spontaneous and endothermic progress of Cr(VI) adsorption on PPy-Loof. The electrostatic attraction, ion exchange interaction, as well the reduction effect, were supposed as the main mechanism of Cr(VI) removal by PPy-Loof.
Deciphering influence of donor age on adipose-derived stem cells: paracrine function and angiogenic potential
Authors: TROTZIER Chloe , BELLANGER Clement , ABDESSADEQ Hakima , DELANNOY Philippe , MOJALLAL Ali , AUXENFANS Celine
Published: February 2024

Background: As fat grafting is commonly used as a filler, Adipose-derived stem/stromal cells (ASC) have been reported to be key player in retention rate. Paracrine and differentiation potential of those cells confer them strong pro-angiogenic capacities. However, a full characterization of the influence of aging on ASC has not been reported yet. Here we’ve investigated the effect of age on paracrine function, stemness and angiogenic potential of ASC.
Methods: ASC were extracted from young and old adult donors. We assessed stromal vascular fraction cell populations repartition, ASC stemness potential, capability to differentiate into mesenchymal lineages as well as their secretome. Angiogenic potential was assessed using a sprouting assay, an indirect co-culture of ASC and dermal microvascular endothelial cells (EC). Total vascular network length was measured, and co-culture soluble factors were quantified. Pro-angiogenic factors alone or in combination as well as ASC-conditioned medium (CM) were added to EC to assess sprouting induction.
Results: Decrease of endothelial cells yield and percentage is observed in cells extracted from adipose tissue of older patients, whereas ASC percentage increased with age. Clonogenic potential of ASC is stable with age. ASC can differentiate into adipocytes, chondrocytes and osteoblasts, and aging does not alter this potential. Among the 25 analytes quantified, high levels of pro-angiogenic factors were found, but none is significantly modulated with age. ASC induce a significantly longer vascular network compared to fibroblasts, and no difference was found between young and old ASC donors on that parameter. Higher concentrations of bFGF, G-CSF, HGF and IL-8, and lower concentrations of VEGF-C were quantified in EC/ASC co-cultures compared to EC/fibroblasts co-cultures. EC/ASC from young donors secrete higher levels of VEGF-A compared to old ones. Neither soluble factor nor CM without cells are able to induce organized sprouts, highlighting the requirement of cell communication for sprouting. CM of ASC donor inducing long vascular network can restore pro-angiogenic potential of ASC donor inducing short vascular network.
Conclusion: Our results show cells from young and old donors exhibit no difference in all assessed parameters, suggesting all patients could be included in clinical applications. We emphasized the leading role of ASC in angiogenesis process, without impairment with age, but further studies are required to better understand the mechanistic of this phenomenon.
Wavelet-based Arcing Signal Source Localization Algorithm using a Compact Multi-square Microstrip Antenna
Authors: Amirruddin Melaty , Adzman Mohd Rafi , Affendi Nur Adyani Mohd , Isa Muzamir , Idris Muhd Hafizi , Halim Syahirah Abd , Lehtonen Matti
Published: February 2024

Ensuring power system safety involves effective arc fault detection and localization. Existing devices struggle to differentiate normal and abnormal conditions, especially in confined spaces, posing precision challenges. Placing antennas strategically around the arc aids in detecting electromagnetic radiation, even in limited areas. This enables valuable data collection for real-time monitoring. To address these challenges, this paper proposes integrating experimental work using a compact multi-square microstrip antenna and signal processing techniques. The study compares the effectiveness of three signal processing approaches: threshold, Discrete Wavelet Transform (DWT), and Continuous Wavelet Transform (CWT). The signal processing technique separates genuine arc signals from background noise by identifying unique characteristics and isolating the dominant frequency. The Time of Arrival (ToA) is measured and used in Least Square (LS) and Gauss-Jordan Elimination (GJE) methods to calculate the arc source location. The outcomes illustrate the precision of the proposed model in detecting and pinpointing arc source signals, with error margins ranging from 6.15% to 7.13% for the CWT technique, 6.88% to 7.89% for the DWT technique, and 7.99% to 8.44% for the threshold technique. These results hold promise for enhancing the integration of experimental approaches in assessing arcing conditions, thereby addressing challenges in insulation systems.