bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel Portfolio Selection Models with Parametric Entropy and Sensitivity Analysis under Hesitant Fuzzy Environment
Authors: Deng Xue , Zhao Jinyao , Fu Qihan
Published: August 2022

In most risk investments, it is difficult for investors to acquire enough precise data, so they have to rely on uncertain information to make decisions. Taking advantage of hesitant fuzzy sets, whose membership degree is composed of several values in the closed interval between 0 and 1, thus it is easier to depict the uncertainty of events in the practical applications. Based on the above facts, this paper focuses on the portfolio selection problem under hesitant fuzzy environment, using hesitant fuzzy sets’ membership degrees to describe investors’ hesitation and adopting parametric entropy to measure fuzzy sets’ uncertain degree. Firstly, we present a parametric entropy formula satisfying the axiomatic definition of hesitation fuzzy entropy through serious mathematical proof and discussion. Secondly, two portfolio models with parametric hesitant fuzzy entropy are proposed, which adopt score function and entropy to describe return and risk, respectively. In addition, a constraint trisection approach is developed to solve our proposed models according to investors’ different risk preferences. Finally, a case study is conducted to highlight the effectiveness of the proposed models. Sensitivity analysis is carried out to explore the effect of parameter changes on portfolio return, risk and investment ratio, which fully manifest the flexibility of parametric entropy. We come to the conclusion from multiple sets of data that parameter setting can reasonably reflect investors’ information preference. Compared with conventional method, not only parametric entropy introduced as a risk measure for portfolio models, but also the explicit model solving processes listed in this paper contribute to portfolio under hesitant fuzzy environment.
A Theoretical Study to Estimate Milk Adulteration Using Surface Plasmon Technique
Authors: V Prathap , S Arun Prakash
Published: August 2022

In the proposed work, a biosensor has been proposed to detect adulteration in milk. The rapid detection of adulteration such as Urea, Melamine, and Salmonella is a major concern for the food industry. In the present study, urea, melamine, and salmonella are detected in cow and buffalo milk using SPR based technique. The performance of the proposed sensor for urea detection in buffalo and cow milk is 37.952°/RIU and 38.44°/RIU, respectively. In contrast, the sensitivity detected by the proposed SPR sensor for the salmonella and melamine salmonella adulteration in the milk is 22.0025°/RIU and 179.125°/RIU, respectively.
Mapping regional vulnerability in Europe’s energy transition : development and application of an indicator to assess declining employment in four carbon-intensive industries
Authors: McDowall William , Reinauer Tobias , Fragkos Panagiotis , Miedzinski Michal , Cronin Jennifer
Published: August 2022

Europe’s transition to an energy system compatible with limiting global heating to 1.5°C will require radical changes in energy systems. While this will create substantial new growth industries in clean technologies, some currently important economic activities will decline. The impacts of that transition will not be the same for all regions. We map the economic vulnerability of European regions to ambitious decarbonisation scenarios. To do so, we develop a composite vulnerability indicator that combines each region’s share of employment in a set of high carbon industries with other dimensions of vulnerability and resilience. We then explore how regional patterns of vulnerability are influenced by the technology pathway to 2050, using four scenarios modelled using the European PRIMES model. We show that economic vulnerability to the low-carbon transition is regionally concentrated, with some regions combining high employment shares in industries expected to decline with weak adaptive capacity and high pre-existing unemployment. We also show that there is little variation in regional vulnerability arising from different transition pathways. All scenarios compatible with 1.5°C involve large declines in all high-carbon sectors we analyse, and as a result scenario variation does not lead to large variation in relative vulnerability of regions. The results highlight regions that may be in need of additional policy support to diversify their economies and achieve a just transition.
Reinforcement Learning-Based Rate Adaptation in Dynamic Video Streaming
Authors: Hafez Nada A. , Hassan Mohamed S. , Landolsi Taha
Published: August 2022

Video streaming stands out as the most significant traffic type consumed by mobile devices. This increased demand has been a major driver for research on bitrate adaptation algorithms. Bitrate adaptation ensures high user-perceived quality, which, in turn, correlates with higher profits for content providers and delivery systems. Dynamic adaptive streaming over HTTP (DASH) is a widely adopted video streaming standard utilized by service providers to provide competitive quality of experience (QoE). It is capable of providing seamless streaming via uncertain network conditions by switching across different video qualities and their corresponding video segment bitrates. The complexity of the video streaming environment makes it a good candidate for different learning-based approaches. Accordingly, this paper proposes a reinforcement-learning (RL) deep Q-network called DQNReg, that enhances the classical deep Q-learning method. A segment-wise QoE-based reward function is formulated so that the learning strategy can converge towards maximizing the QoE outcome. The proposed RL-based adaptation approach is evaluated using trace-based simulation for both wireless local area network channels and 5G mobile channels. The performance of this RL-based method is compared to three methods: A heuristic method, a model-based method, and a classical learning-based method. The comparison shows that the RL-based method converges faster while achieving a high QoE score. In addition, it reduces the re-buffering duration while maintaining higher video quality and relatively lower quality variations.
Clinical Factors Influencing Long-Term Survival in a Real-Life Cohort of Early Stage Non-Small-Cell Lung Cancer Patients
Authors: Torrente Maria , Sousa Pedro A. , Guerreiro Gracinda R. , Franco Fabio , Hernández Roberto , Parejo Consuelo , Sousa Alexandre , Campo-Cañaveral José Luis , Pimentão João , Provencio Mariano
Published: August 2022

BACKGROUND
Current prognosis in oncology is reduced to the tumour stage and performance status, leaving out many other factors that may impact the patient´s management. Prognostic stratification of early stage non-small-cell lung cancer (NSCLC) patients with poor prognosis after surgery is of considerable clinical relevance. The objective of this study was to identify clinical factors associated with long-term overall survival in a real-life cohort of patients with stage I-II NSCLC and develop a prognostic model that identifies features associated with poor prognosis and stratifies patients by risk.
METHODS
This is a cohort study including 505 patients, diagnosed with stage I-II NSCLC, who underwent curative surgical procedures at a tertiary hospital in Madrid, Spain.
RESULTS
Median OS (in months) was 63.7 (95% CI, 58.7–68.7) for the whole cohort, 62.4 in patients submitted to surgery and 65 in patients submitted to surgery and adjuvant treatment. The univariate analysis estimated that a female diagnosed with NSCLC has a 0.967 (95% CI 0.936–0.999) probability of survival one year after diagnosis and a 0.784 (95% CI 0.712–0.863) five years after diagnosis. For males, these probabilities drop to 0.904 (95% CI 0.875–0.934) and 0.613 (95% CI 0.566–0.665), respectively. Multivariable analysis shows that sex, age at diagnosis, type of treatment, ECOG-PS, and stage are statistically significant variables (p < 0.10). According to the Cox regression model, age over 50, ECOG-PS 1 or 2, and stage ll are risk factors for survival (HR > 1) while adjuvant chemotherapy is a good prognostic variable (HR < 1). The prognostic model identified a high-risk profile defined by males over 71 years old, former smokers, treated with surgery, ECOG-PS 2.
CONCLUSIONS
Surgery plus adjuvant chemotherapy was associated with the best long-term OS in our patients. The prognostic model identified Age, Sex, Stage and ECOG-PS as significant factors to explain the probability of survival.
Datura Stramonium leaves extract Silver Nanoparticles regulates PINK1 gene in Parkinson’s disease model of Drosophila melanogaster
Authors: SHIVANNA DEVARAJU KURAMKOTE , G Gopinath , Hanumanthappa Ramesha , Babu Yarajarla Ramesh , Abbigeri Megha Basavaraj , Ajanal Manjunath , Nanjaiah Hemalatha
Published: August 2022

In recent years, several eco-friendly processes for the synthesis of silver nanoparticles (AgNPs) are increasing; they have tremendous applications in the field of diagnosis and therapeutic values for various diseases /disorders. In this article the green synthesis of Datura stramonium leaves extract silver nanoparticles (DS-AgNPs) was carried out and are characterized for different properties like reduction of Ag + to Ag◦, absorption maxima, functional group of secondary metabolites, crystalline structure, morphology, and size by using UV-Vis spectroscopy, fourier transform infrared spectroscopy (FITR) X-ray spectroscope (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM) respectively. Further the effects of DS-AgNPs on WT Park TM3 SB and WI Park 25 Parkinson’s mutant Drosophila melanogaster was assessed by the Negative geotaxis assay and PINK 1 gene expression. Treatment with DS-AgNPs exhibited increased geotaxis behavior and with a positive survival percentage, finally PINK1 was found to be down regulated as the treatment concentrations increased in WI Park 25 mutant but up regulated in WT Park TM3 SB mutant PD model. Although more molecular mechanism needs to be understood, however the use of DS-AgNPs can be a promising treatment strategy for the PD.
Promising anti-Toxoplasma activity of 1,2,3-triazole tethering sulfonamide moiety; synthesis; characterization and in vitro study
Authors: Arafa Fadwa Mostafa , Osman Doaa Hassan , Tolba Mona Mohamed , Rezki Nadjet , Aouad Mohamed R , Hagar Mohamed , Osman Mervat , Said Heba
Published: August 2022

Toxoplasmosis is an infection that prevails all over the world and is caused by the obligate intracellular protozoan parasite Toxoplasma gondii (T.gondii). The current study introduces new lead compounds for the treatment of T.gondii. Three novel 1,2,3-triazoles-based sulfonamide scaffold were designed, synthesized and fully characterized in order to investigate the In vitro toxoplasmacidal potency using Vero cells as host for T. gondii. Selectivity index parameter was used to express compounds efficacy in the inhibition of T. gondii proliferation, whereas the scanning electron microscopy technique was used to assess the ultrastructural changes. A significant anti-toxoplasma activity was observed with hybrid molecules compared to the sulfadiazine as a positive control. The results showed that the IC50 (inhibitory concentration) of the investigated compounds 3(a,b,c) were recoded as 10.335 µg/ml, 20.106 µg/ml and 5.574 µg/ml, respectively; while the used sulfadiazine exhibited 49.794 µg/ml as IC50. The investigated 1,2,3-triazole-sulfadrug molecular conjugates 3(a,b,c) revealed selectivity index at 21.028, 8.356, 28.595, respectively. All compounds were highly selective than the gold standard drug which showed selectivity index of 7. Scanning electron microscopy (SEM) revealed that most tachyzoites had remarkable morphological changes after 2 hours of exposure. To reveal that compound 3c exhibits the highest activity against T. gondii.
Characterization of Capa Peptide and Its Receptor in Bemisia Tabaci
Authors: Thakur Sudeshna , Jindal Vikas
Published: August 2022

The diuresis process in insects is regulated by CAPA neuropeptides, which activate the specific cognate receptor i.e CAPAr. In this study, we characterized the CAPAr gene (BtabCAPAr) in whitefly, Bemisia tabaci Asia II 1 for the first time. The two splicing isoforms of the BtabCAPAr gene i.e BtabCAPAr-1 and BtabCAPAr-2 which included six (421 aa) and five (355 aa) exons, respectively were recorded. The third exon was missing in the BtabCAPAr-2 isoform. The transmembrane topology depicted the presence of seven and five transmembrane regions in BtabCAPAr-1 and BtabCAPAr-2, respectively. The relative BtabCAPAr gene expression in different whitefly life stages revealed the highest (3.76 folds) expression level of the BtabCAPAr gene in the adult stage as compared to the egg stage. The expression of the BtabCAPAr gene in the nymphal and pupal stage did not differ significantly with each other as well as egg stage. Two peptides, CAPA-PVK1 and CAPA-PVK2 were identified through a functional luminescence assay, which strongly activated the BtabCAPAr-1 receptor with very low EC50 values of 0.067 nM and 0.053 nM, respectively. The basic information generated in the study will help develop biostable peptides, which can be tested further and may lead to the development of new generation insecticides.
Assessing and comparing the emotional intelligence in generalist and psychiatric nurses
Authors: Alshowkan Amira , Kamel Neama , Alghamdi Rayanah
Published: August 2022

Aim: Emotional intelligence (EI) is linked to individual well-being and has a positive effect on patient care. This study was aimed at assessing and comparing the EI levels demonstrated by students at one university in Saudi Arabia who studied had psychiatric and mental health nursing and those who had studied nursing fundamental of nursing courses but had not yet taken psychiatric nursing courses. Design: A descriptive and comparative study designMethods: Data were collected from all second- and third-year nursing students using the Schutte Self-Report Emotional Intelligence Test (SSEIT). Results: Finding indicate that students who had studied only nursing fundamentals demonstrated lower EI than those who were completing psychiatric and mental health nursing courses. Moreover, increased EI was related to the education level of the participant’s father and being the eldest child in the family
Efficacy and safety of vonoprazan-based quadruple therapy for the eradication of Helicobacter pylori in patients with peptic ulcers: a pooled analysis of two randomized, double-blind, double-dummy, phase 3 trials
Authors: Hou Xiaohua , Wang Jiangbin , Du Qin , Tian Dean , Hu Naizhong , Liu Deliang , Zhou Fang , Xie Li , Gu Liqun , Kudou Kentarou , Zhang Shutian
Published: August 2022

BackgroundHelicobacter pylorieradication is a key goal in treating peptic ulcers withH. pyloriinfection, a disease highly prevalent in Asia. We present a pooled analysis of two randomized, double-blind, double-dummy, phase 3 studies to evaluate the efficacy and safety of vonoprazan-based bismuth-containing quadruple therapy inH. pylorieradication.MethodsPatients aged ≥18 years with endoscopically confirmed duodenal or gastric ulcers were randomized 1:1 to receive vonoprazan 20 mg or lansoprazole 30 mg once daily for up to 6 or 8 weeks, wherebyH. pylori-positive patients received vonoprazan- or lansoprazole-based bismuth-containing quadruple therapy for the first 2 weeks.H. pylorieradication was determined by a carbon-13 urea breath test at a follow-up visit 4 weeks post-treatment.ResultsTheH. pylorieradication rate was90.6% with vonoprazan vs 85.2% with lansoprazole (difference: 5.4%; 95% confidence interval [CI]: −0.1, 10.8).H. pylorieradication was 7.1% (95% CI: 1.4, 12.8) and 12.6% (95% CI: 3.9, 22.0) higher in patients aged <65 years and current smokers, respectively, with vonoprazan vs lansoprazole. In the Chinese subpopulation, theH. pylorieradication rate was 92.0% with vonoprazan vs 86.0% with lansoprazole (difference: 6.1%; 95% CI: 0.5, 11.7). Treatment‑emergent adverse events occurred in 72.7% vs 62.6% of patients who wereH. pyloripositive at baseline in the vonoprazan vs lansoprazole arm.ConclusionsH. pylorieradication with vonoprazan-based quadruple therapy was indicated to be non-inferior to lansoprazole-based quadruple therapy and exceeded 90%, a clinically relevant threshold for determining the efficacy ofH. pylorieradication regimens. (ClinicalTrials.gov identifier: NCT03050359; NCT03050307).
Steady-state Peierls transition in nanotube quantum simulator
Authors: Zhang Lin , Bhattacharya Utso , Bachtold Adrian , Forstner Stefan , Lewenstein Maciej , Pistolesi Fabio , Grass Tobias
Published: August 2022

Quantum dots placed along a vibrating nanotube provide a new quantum simulation platform that can directly address the electron-phonon interaction. This offers promising prospects for the search of new quantum materials and the study of strong correlation effects. As this platform is naturally operated by coupling the dots to an electronic reservoir, state preparation is straightforwardly achieved by driving into the steady state. Here we show that for intermediate electron-phonon coupling strength, the system with spin-polarized quantum dots undergoes a Peierls transition into an insulating regime which exhibits charge-density wave order in the steady state as a consequence of the competition between electronic Coulomb repulsive interactions and phonon-induced attractive interactions. The transport phenomena can be directly observed as fingerprints of electronic correlations. We also present powerful novel methods to numerically capture the physics of such an open electron-phonon system at large numbers of phonons. Our work paves the way to study and detect novel correlated electron-phonon physics in the nanotube quantum simulator with current experimentally accessible techniques.
Eating behavior and physical activity leading to gender differences in overweight and obesity among college students in China
Authors: Mu Lianwei , Qiu Ping-xue , Wang Hai-ying
Published: August 2022

Overweight and obesity are showing an increasing prevalence among college students. But gender differences related to overweight and obesity in Chinese college students have not been adequately characterized. This cross-sectional study aimed to investigate the gender differences in overweight and obesity among college students, then, investigate why these gender differ-ences exist. A total of 622 undergraduate students (females: N = 245, male: N = 377), aged 18–23 years, were recruited from the Hebei Sport University in China. Anthropometric data, physical activity and sedentary behaviors, eating behaviors (cognitive restraint, uncontrolled eating, and emotional eating) and food addiction were collected through anthropometric measurements and questionnaires that included the International Physical Activity Questionnaire short-form (IPAQ-SF), the Modified Food Addiction Scale version 2.0 (mYFAS 2.0), and the Three Factor Eating Questionnaire (TFEQ). Here, we show that female college students had a significantly higher prevalence of overweight and obesity (Female: BFP ≥ 25%; Male: BFP ≥ 20%) than male students. Meanwhile, Female college students had a higher mean body fat percentage (BFP) and a lower waist circumference, waist-to-hip ratio, visceral fat area, fat-free mass, muscle mass, and skeletal muscle mass compared to male college students. Additionally, female college students were more likely to be moderate physical activity than males, while male college students were more likely to be severe physical activity. Female college students had significantly higher mean scores for cognitive restraint, uncontrolled eating, and emotional eating than males. Our findings indicated that the higher prevalence of overweight and obesity rates in female college students than male students may be due to de differences in physical activity and eating behavior.
Groundwater quality assessment in Harrat Khaybar, western Saudi Arabia
Authors: Alshehri Fahad , El-Sorogy Abdelbaset S.
Published: August 2022

Evaluating the suitability of groundwater for human use is essential for water supply and health in arid and semi-arid regions. In this work, a total of 68 groundwater samples were collected from Harrat Khaybar, western Saudi Arabia to evaluate the suitability of groundwater for drinking and irrigation purposes and to document the controlling mechanisms using pollution indices and multivariate statistical methods. The results showed that the average values of the ions Cl–, SO42–, HCO3–, NO3–, Na+, Ca2+, Mg2+, and total dissolved solids (TDS) were greater than the permissible limit for drinking water while the average values of heavy metals (HMs) were less than the permissible limit, with exceeding limits of Cr, Se, As, Zn, and Pb in some individual samples. Piper diagram indicated that 47.10% of the water samples are of Na-K-SO4-Cl type, 23.51% of Ca-Mg-CO3-HCO3 type, 23.51% of Ca-Mg-SO4-Cl type, and 5.88% of Na-K-CO3-HCO3 type. Based on the groundwater quality index (GWQI), 29 of the groundwater samples were categorized as excellent and good water for drinking purposes, while 29 samples fell under poor, very poor water, and unsuitable for drinking. Additionally, results of heavy metal pollution index (HPI) indicated that all water samples fell within the low pollution category, while the metal index (MI) results indicated that 35 samples fell within very pure, pure, and slightly affected categories, while 33 samples fell in the moderately, strongly, and seriously affected categories. Results of electrical conductivity (EC), sodium adsorption ratio (SAR), sodium percentage (%Na), Kelly’s ratio (KR), and magnesium ratio (MR) revealed that 33.82–98.5 % of the water samples are suitable for irrigation depending on the parameter type. Ions exchange reactions and dissolution of carbonates, evaporites, and silicates, as well as industrial and domestic effluents and intensive use of fertilizers and pesticides were the natural and athropogenic factors controlling the groundwater geochemistry in the study area and HM pollution in some wells.
Vitro -derived hop (Humulus lupulus L.) leaves and roots as source of bioactive compounds: antioxidant activity and polyphenolic profile
Authors: CHIANCONE BENEDETTA , Guarrasi Valeria , Leto Leandra , Vecchio Lorenzo Del , Calani Luca , Ganino Tommaso , Galaverni Martina , Cirlini Martina
Published: August 2022

Bioactive compounds extracted from plant essences are of great value for those enterprises interested in natural products; plant tissue culture techniques guarantee a reliable and constant biomass production. Hop (Humulus lupulus L.), with its wealth in bioactive compounds, is an unvaluable resource. The present study focused on the characterization of vitro-derived leaves and roots of two hop genotypes, Cascade and Gianni. Extracts obtained from the selected hop explants were investigated, determining their polyphenolic content as their antioxidant capacity, applying DPPH, ABTS and FRAP assays; moreover, phenolic extract molecular profile was obtained through UHPLC-MS/MS. Results confirm the wealthy in bioactive compounds and the antioxidant properties of vitro-derived hop explants tested; furthermore, the qualitative characterization evidenced that extracts obtained from vitro-derived hop tissues are composed of twenty one different compounds and contain the same hop antioxidant molecules, as well as xanthohumol and isoxanthohumol, also present in open field grown hop plants, such as α-acids and β-acids. Achievement obtained are encouraging and lays the groundwork to further investigate the potential of vitro-derived hop plantlets as bioactive compounds source.
A Study On Prediction Of Lung Cancer Using Machine Learning Algorithms
Authors: Gupta Abhishek , Zuha Zuha , Ahmad Israr , Ansari Zeeshan
Published: August 2022

Lung cancer is the second most dangerous disease worldwide which is curable if its diagnosis is done in earlier stages. Even with the rise in cancer diseases, researches have shown that the mortality rate of cancer patients is less. For the treatment of cancer patients, Machine learning and AI have been researched and employed for the early detection of this disease in the past years. Biomedical image processing and detection of data have been used in combination in order to devise new techniques. In this paper, image classification was performed and machine learning algorithms were applied on lung cancer disease dataset to calculate measures such as accuracy, sensitivity, etc. K-NN, Random forest and SVM algorithms have been used to analyze the initial stage lung cancer by applying these on the lung cancer dataset.
Loss of participation among young adults in the prospective disaster cohort study of the Comprehensive Health Check in the Fukushima Health Management Survey after the Great East Japan Earthquake
Authors: Yamamoto Kana , Takita Morihito , Kami Masahiro , Tani Yuta , Yamamoto Chika , Tianchen Zho , Ohira Tetsuya , Maeda Masaharu , Yasumura Seiji , Sakai Akira , Hosoya Mitsuaki , Okazaki Kanako , Yabe Hirooki , Tsubokura Masaharu , Shimabukuro Michio , Ohto Hitoshi , Kamiya Kenji
Published: August 2022

Background
The present study aimed to clarify the characteristics of young evacuees who had missed the Comprehensive Health Check of the Fukushima Health Management Survey after the Great East Japan Earthquake in 2011.
Methods
The Fukushima Health Management Survey has been conducted as a prospective cohort study to evaluate health status of evacuees annually after the great earthquake in 2011. This study focused on the annual participation rate in the Comprehensive Health Check of young evacuees aged between 20 and 37 years who had been evacuated due to the Fukushima Daiichi Nuclear Power Plant accident. Exploratorily, we compared the characteristics of subjects who participated in 2011 only with those who had in both 2011 and after 2012.
Results
The participation rate was estimated at 26.6% (9,720 among 36,502 residents) and 15.6% (5,691 residents) in 2011 and 2012, respectively. Multivariate analysis revealed the following characteristics in 2011 as independent predictors of non-participation after the second year of the survey: age ≤ 24 years (adjusted odds ratio 2.07, 95% confidence interval: 1.82–2.36), 25–29 years of age (1.25, 1.12–1.41), men (1.51, 1.37–1.66), evacuation outside the municipality but within Fukushima Prefecture (1.52, 1.38–1.67), evacuation outside the Fukushima Prefecture (1.29, 1.14–1.46), smoking habit (1.33, 1.21–1.46), and drinking habit (1.19, 1.09–1.30). A medical history of heart disease and a body mass index ≤ 18.5 kg/m2 showed opposite odds ratios which indicates the association with continuous participation (0.48, 0.30–0.76, 0.84, 0.73–0.97, respectively).
Conclusions
We observed deteriorated participation in the prospective study of the Comprehensive Health Check of the Fukushima Health Management Survey among evacuees of a younger age group, men, those evacuated outside their municipalities, and those with smoking and drinking habits. Hence, the cohort study may have missed certain population groups indifferent to disaster-related health problems. Thus, it is necessary to consider various measures to increase the participation rate in the disaster cohort study to understand the long-term health effects of disasters on younger residents in evacuation zones.
The association of self-efficacy, awareness of aged life, and retirement preparation with psychological well-being among aged
Authors: Lee BO MI , Lee Kang-Sook , Lee Dahyeon
Published: August 2022

Background
This study was conducted to evaluate the association of self-efficacy, awareness of aged life and retirement preparation with psychological well-being among middle-aged and elderly people.
Methods
This study used 285 men and women aged 40 to 65 years old, including public officials and public enterprise employees who participated in retirement education hosted by public institutions living in Seoul and Gyeonggi Province, as research data. The survey period was conducted from November 10, 2020 to February 28, 2021, and the collected data were analyzed using SPSS 22.0 as frequency analysis, t-test, ANOVA, regression and Sobel Test.
Result
Self-efficacy, perception of old life, retirement preparation, and psychological well-being according to social demographic characteristics differed significantly in civil servants and professionals, and the higher income and educational background. Correlation between the sense of self-efficacy, awareness of aged life, retirement preparation, and psychological well-being of middle-aged and elderly people. The perception of old life and self-efficacy have a positive impact on retirement preparation, and the perception of old life through retirement showed significant differences in psychological well-being, confirming that it is a variable that can improve psychological well-being.
Conclusion
Self-efficacy and perception of old life are highly related to improving psychological well-being, so continuous research should be needed to improve self-efficacy and old life awareness through retirement preparation and health promotion programs using public pensions.
Extension of the Modified Compression Field Theory for FRP Reinforced Masonry Elements
Authors: Bondarabadi Hosseinali Rahimi , karimipanah Ahmad
Published: August 2022

Modified Compression Field Theory (MCFT) is recognized as a non-linear procedure in the analysis of reinforced concrete structures, which was introduced for calculating the response of reinforced concrete elements subjected to shear. This analysis is based on the stress-strain relation of concrete and reinforcement, by means of an iterative method called the secant stiffness. This study implements the MCFT through an innovative approach based on the stress-strain relation of brick and fiber reinforced polymer (FRP) composite to analyze the in-plane behavior of FRP- reinforced masonry buildings. Further, failure mechanism and FRP debonding are considered. The analysis is performed through a nonlinear finite element program. To this end, non-linear formulations are conducted following by way of the nonlinear iterative secant stiffness procedure. The accuracy of the proposed model are validated is confirmed against the experimental findings available in the literature.
Identification of key genes related to immune infiltration in cirrhosis via bioinformatics analysis
Authors: Du Tong-Yue , Gao Ya-Xian , Zheng Yi-Shan
Published: August 2022

Background:Cirrhosis is the most common subclass of liver disease worldwide and correlated to immune infiltration. However, the immune-related molecular mechanism underlying cirrhosis remains obscure.Methods:Two gene expression profiles GSE89377 and GSE139602 were investigated to identify differentially expressed genes (DEGs) related to cirrhosis. Enrichment analysis for DEGs was conducted. Next, the immune infiltration of DEGs was evaluated using CIBERSORT algorithm. The hub DEGs with tight connectivity were identified using the String and Cytoscape databases, and the expression difference of these hub genes between normal liver and cirrhosis samples was determined. Finally, the association between hub DEGs and immune cell infiltration was explored by Spearman method.Results:Among the 299 DEGs attained, 136 were up-regulated and 163 were down-regulated. Then the enrichment function analysis of DEGs and CIBERSORT algorithm showed significant enrichment in immune and inflammatory responses. And four hub DEGs (ACTB, TAGLN, VIM, SOX9) were identified. Finally, the immune infiltration analysis indicated that, these hub DEGs were highly related to immune cells.Conclusions:This study revealed key DEGs involved in inflammatory immune responses of cirrhosis, which could be used as biomarkers or therapeutic targets of cirrhosis.
In-orbit demonstration of a re-trainable Machine Learning Payload for processing optical imagery
Authors: Mateo-García Gonzalo , Veitch-Michaelis Josh , Purcell Cormac , Longepe Nicolas , Mathieu Pierre Philippe , Reid Simon , Anlind Alice , Bruhn Fredrik , Parr James
Published: August 2022

Cognitive cloud computing in space (3CS) describes a new frontier of space innovation powered by Artificial Intelligence, enabling an explosion of new applications in observing our planet and enabling deep space exploration. In this framework, machine learning (ML) payloads --isolated software capable of extracting high level information from onboard sensors-- are key to accomplish this vision. In this work we demonstrate, in a satellite deployed in orbit, a ML payload called ‘WorldFloods’ that is able to send compressed flood maps from sensed images. In particular, we perform a set of experiments to: (1) compare different segmentation models on different processing variables critical for onboard deployment, (2) show that we can produce, onboard, vectorised polygons delineating the detected flood water from a full Sentinel-2 tile, (3) retrain the model with few images of the onboard sensor downlinked to Earth and (4) demonstrate that this new model can be uplinked to the satellite and run on new images acquired by its camera. Overall our work demonstrates that ML-based models deployed in orbit can be updated if new information is available, paving the way for agile integration of onboard and onground processing and "on the fly" continuous learning.
Soil Arsenic toxicity impact in the growth and C-assimilation of Eucalyptus nitens
Authors: Ramalho José C. , Pelica João , Lidon Fernando C. , Silva Maria M. A. , Simões Maria M , Guerra Mauro , Reboredo Fernando H.
Published: August 2022

The selection of suitable plant species that can live in contaminated and abandoned mining areas is a goal environmental managers and policy makers. In this framework, the use of a fast-growing forestry species such as Eucalyptus nitens in the recovery of As from artificial contaminated soils was studied during a long-term experiment. Roots can accumulate levels ranging between 69.8 and 133 µg g− 1 for plants treated with 100 As and 200 As, respectively, while leaves between 9.48 µg g− 1 (200 As) and 15.9 µg g− 1 (100 As) without apparent morphological damage and toxicity symptoms. The performance of the photosynthetic apparatus showed a gradual impact in some gas exchange parameters such as net photosynthetic rate (Pn), stomatal conductance to H2O (gs) and the transpiration rate (E), particularly with the use of the highest As concentration (200 As), but without significant impacting the PSII performance. The effects of As on the uptake and translocation of Ca, Fe, K and Zn revealed two major interferences. The first one related with Zn where a moderate antagonism was detected, and the second one related with Fe, where a particular enrichment in E. nitens leaves was noted in both As treatments. Thus, it seems to exist a synergistic action with impact in the levels of the photosynthetic pigments in As treated plant leaves, compared with control plants. In face of the acquired data, E. nitens must be considered as an alternative when phytoremediation processes are put in practice in our country.
Health behavior, life-years loss and the educational gradient
Authors: Ibarra-Sanchez Ana Silvia , Olsen Jan Abel , Finn Iselin Caroline , Wisløff Torbjørn
Published: August 2022

Our objective is to explore how educational differences in health behavior may impact life expectancy. Cross-sectional data from the Tromsø Study conducted in 2015/2016 was used to explore the relationship between education and reported lifestyle behavior. Published estimates of life-year losses associated with health behaviors were combined with the participants’ health behavior to give personal estimates of life expectancy loss. Then, we assessed the distribution of this life loss across education levels to give an indication of the social gradient in loss of life expectancy due to health behaviors as reported in 2015/2016. Considerable educational inequalities were observed in lifestyle behavior in the Tromsø Study. According to the published literature, smoking was found to be associated with the largest life-loss, followed by low physical activity and obesity. The number of respondents following a healthy lifestyle and thereby facing the smallest loss of life expectancy increased with every level of education, whereas the proportion of individuals that did not adhere to healthy lifestyle recommendations and with the largest potential life loss decreased with educational level. There is a clear education gradient in the adherence of health behavior recommendations that could lead to educational differences in life expectancy.
Morphometric and Clinical Evaluation of Sphenopalatine Foramen on Computed Tomography Images
Authors: Şeker Büşra , Açar Gülay , Çiçekcibaşı Aynur Emine , Aydoğdu Demet
Published: August 2022

Purpose
This study aimed to investigate the effect of anatomical variations in the sphenopalatine foramen and the lateral nasal wall on sphenopalatine foramen-related morphometric measurements.
Methods
Temporal bone multidetector computed tomography records of 153 patients were evaluated. Morphometric measurements were made between the fixed anatomical landmarks and the sphenopalatine foramen. Number, shape, localization variation of the sphenopalatine foramen, concha bullosa, and septum deviation were noted.
Results
No significant difference was detected between the right-left sides for all distances measured except SPF-CA and SPF-BL and most of the measurements were higher in males. In addition, statistical analysis of the obtained morphometric data was performed according to age groups. Classified the shape of the sphenopalatine foramen five types and reported that the most common irregularly shaped (37.3%). In our study, 91.2% single, 7.8% double, and 1% triple sphenopalatine foramen were detected. The location of sphenopalatine foramen was reported as the most common type I. No statistically significant relationship could be determined between morphometric data and septum deviation types. SPF-NF, SPF-ML, OSPF-ANS, and HSPF-ANS measurements were found to be significantly smaller in the presence of concha bullosa, whereas SPFA was found to be higher.
Conclusion
This study revealed a significant relationship between the morphometric measurements of the sphenopalatine foramen and concha bullosa, while septum deviation types did not affect morphometric results. For a safer and more effective surgery with prevention of iatrogenic complications, a surgeon should be aware of this correlation, especially in endoscopic sphenopalatine foramen approaches.
COVID-19 absenteeism in a meat processing abattoir during sustained community transmission in Central Queensland, Australia
Authors: Krasnova Svetlana , Smoll Nicolas , Khandaker Gulam
Published: August 2022

Objective
Here we present the evaluation of the effect of the new COVID-19 national policy for the management of cases and close contacts and school re-opening on staff absenteeism in a meat processing/abattoir in Central Queensland, Australia during sustained community transmission.
Results description:
The new definition of a close contact and 7-day isolation period appeared to be minimizing the burden on absenteeism and the critical essential workforce model to helping this further.
Three modes of the east Asia summer monsoon influencing Eastern China
Authors: Liu Yong-he , Hu Yong-Hong , Feng Jin-Ming
Published: August 2022

East Asia Summer Monsoon (EASM) is the primary circulation affecting boreal summer precipitation in eastern China and is mainly dominated by the recession and extension of the Western Pacific Subtropical High (WPSH). Based on monthly datasets, previous studies have mainly focused on the intensity and variability of the WPSH, in order to obtain potential predictions of the EASM. Here, based on daily wind anomalies, in addition to the most common mode of WPSH, two additional modes are found in the summer circulation over China. The second mode (M2) seems irrelevant to the influence of WPSH over China. The positive phase of M2 favors precipitation in the areas south of the Yangtze River and the western Northeast China, but is unfavorable to precipitation in North China. M2 poses an India Ocean-East China (or west-east) dipole pattern. The positive phase of M2 seems associated with a strong, large, spatially continuous but southerly shifted subtropical high that connects the WPSH and the subtropical high over the India Peninsular/Indian Ocean, leading to a strong eastward wind flow from the northern India Ocean to the northwest Pacific. Accompanying with this large subtropical high system is a cyclonic circulation over the area of Southeastern China and the East China Sea. The positive phase of the third mode (M3) reflects a northward shifted WPSH, which favors precipitation in northern China and a small part of South China, but unfavorable to precipitation in the Yangtze River basin. M3 is associated with a strong south-north dipole structure of sea level pressure. The south side of this structure is over the Maritime Continent, and its north side is over the Asia continent, but the variation of sea level pressure over the Maritime Continent is small compared with that over the Asian continent and the western North Pacific, so this dipole structure can also be regarded as a uniform structure over the Asia continent. Comparatively, M3 has a more pronounced decreasing trend in the past decades, while M2 mainly poses decadal changes.
Evaluation of the correlation between depression and physical activity among older persons with osteoporosis: A cross-sectional study
Authors: Shi Linjun , Zhou Xiaoping , Gao Yueshan , Li Xia , Fang Ronghua , Deng Xuexue
Published: August 2022

Background
Osteoporosis is a common chronic disease in older persons. Physical activity can prevent chronic diseases, as well as many diseases associated with aging. Older persons often suffer from depression and other psychological problems. However, there are few studies on the correlation between depression and physical activity in older persons with osteoporosis in China.
Methods
This cross-sectional study was conducted from June 1, to December 28, 2021. A total of 207 subjects who met the inclusion and exclusion criteria were selected from the outpatient department of West China Hospital and evaluated using a self-designed demographic data questionnaire, the Self-rating Depression Scale (SDS), and the Physical Activity Scale for the Elderly (PASE). Multivariate linear regression was performed to analyze the factors affecting physical activity, and multivariate logistic regression analysis was performed to analyze the factors affecting depression. Spearman’s correlation was used to analyze the correlation between physical activity and depression in older persons with osteoporosis.
Results
A total of 173 valid questionnaires were statistically analyzed. A total of 122 (70.5%) were depressed. The median depression score was 62.5 (24.38), and the median PASE score was 69 (122). Multivariate logistic regression model results showed that physical activity and pain were the main risk factors for depression in older persons with osteoporosis (P < 0.05). Multivariate linear regression model results showed that gender, participation in social activities, activities of daily living status (ADLs), and depression were the main risk factors for physical activity in older persons with osteoporosis (P < 0.05). The results of the correlation analysis showed that physical activity was negatively correlated with depression (R = -0.510, P = 0.000).
Conclusions
We found that physical activity was negatively correlated with depression in older persons with osteoporosis in China. The lower the physical activity scores are, the higher the depression scores. This means that the less physical activity there is, the more serious the depression status. and depression status may reduce physical activity in older persons with osteoporosis. In order to better manage older persons with osteoporosis, medical staff should pay more attention to their physical activity, depression, and influencing factors.
The morphological features of the penile raphe and its clinical application in the circumcision using the disposable circumcision suture device
Authors: Liu Guang-Ming , Xu Zi-Qiang
Published: August 2022

OBJECTIVESto describe the morphological feature of the penile raphe, to solve the frenulum malposition based on the morphological classification of penile raphe in circumcision with the disposable circumcision suture deviceMethodsFrom November 2013 to April 2021, there were 2265 consecutive Chinese patients who underwent circumcision in our hospital. Each patient’s penile raphe morphological feature was recorded and grouped. It could be categorized four type of raphe feature : typeⅠ, the middle raphe; typeⅡ,the middle double raphe or middle band; type Ⅲ, the diamond or lozenge-shaped raphe; type Ⅳ, marked by some hyperpigmentation zone. The case of distinctive type of the penile raphe was treated with different strategy to guarantee the frenum matching. The convexity frenulum cutting site (CFCS) which could be palpated as small rounded eminence tissue at the ventral prepuce during the procedure was also used as an assisting anatomy marker. Other data recorded including operation time, type of anesthesia, intra-operative blood loss, incision healing time, complications and patient satisfactory.RESULTSAccording to the classification system there were 842 (37.2%) cases in type Ⅰ; 258 (11.4%) cases in type Ⅱ; 992 (43.8%) cases in type Ⅲ and 173 (7.6%) cases in type Ⅳ. Following the treatment principle based on the penile raphe feature, no case of notorious frenulum deviation was observed after the 16 cases of frenulum malposition recounted in the first 100 cases in our series. The overall satisfactory rate was high (2185, 93.9%).ConclusionsThe morphological classification of the penile raphe incombinating with the anatomy marker of CFCS will facilitate accurate identification of the frenulum location, better located its right position and cosmetic outcome.
Use of the advanced triple coaxial microcatheter system in superselective arterial embolisation for complex interventional cases: an initial experience with the system.
Authors: Tashi Sonam , Tan Zehao , Gogna Apoorva
Published: August 2022

Learning objective: To share our experience in utilizing the triple coaxial (triaxial) system in super-selective cannulation of arteries for complex embolisation procedures. Background: Percutaneous transcatheter selective embolisation is a widely performed for a myriad of oncologic (e.g. trans-arterial chemo- or radio-embolization) and non-oncologic (e.g. for embolization of bleeding and benign conditions such as uterine fibroid and benign prostate hyperplasia) purposes. The cornerstone of such embolisation procedures is to achieve super-selective cannulation of the arterial supply to the tumour/organ preventing the complication of non-target embolisation. However, the presence of tortuous and complex vascular anatomy can pose a major challenge for achieving this goal. Clinical findings/procedural details: The triaxial system utilizes 2 smaller microcatheter telescoped through each other and over a microwire within an angiographic catheter. We have adopted the use of the triaxial system due to its perceived superior torquability and trackability compared to the conventional coaxial system for cases which superselective cannulation is challenging. The triaxial system is also favourable in situations which the inner microcatheter needs to “sacrificed” after administering embolics (e.g. after administering radionuclides in radioembolization, N-butyl cyanoacrylate (NBCA) glue or dimethyl-sulfoxide (DMSO)). Through a case series with procedural details such as fluoroscopic time, contrast administered etc, we hope to illustrate the utility and efficacy of the triaxial system as well as present pitfalls in its usage. Conclusion:The triaxial system is safe for use in embolization procedures and can confer advantages over conventional co-axial system for specific situations.