bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Dukungan Sosial Terhadap Kualitas Hidup Pada Orang Dengan HIV/AIDS (ODHA) : Literatur Review
Authors: Zuhroh Fatimatuz , Muhid Abdul
Published: January 2023

The number of cases of HIV/AIDS is increasing every year. In Indonesia, cases of HIV/AIDS announced in May 2021 reached 558,618 cases, making it an important matter to pay attention to. Damage that occurs to the organs of a person affected by HIV-AIDS will make that person susceptible to various deadly diseases. A person living with HIV/AIDS will feel hopeless, frustrated, and sad. In addition, the existence of a sense of shame and separation in the community resulted in a decrease in the quality of life of PLWHA. So, it is very important to strive for quality of life in individuals infected with HIV/AIDS by providing enthusiasm, and motivation. Therefore, this paper was made entirely to determine the role of social support with quality of life in individuals with HIV/AIDS. The writing of this article uses the literature review method with reference sources from journals or articles obtained from google scholar and researchgate.net. The results of research from this literature, which show that social support and quality of life are interrelated.
PROBLEMAS DE DERECHO INTERNACIONAL PRIVADO ENTRE ALEMANIA Y MÉXICO
Authors: Prinz von Sachsen Gessaphe Karl August
Published: January 2023

Si cada Estado tiene sus propias reglas conflictuales, entonces una misma situación de hecho puede regirse por diferentes leyes, dependiendo de los juzgados que decidan del caso. En materia de sucesiones, no existen normas uniformes en la relación entre Alemania y México. En el marco de la Unión Europea hay una creciente unificación del derecho conflictual. El Reglamento de la Unión Europea N°650/2012 regula en la materia de sucesiones tanto la competencia internacional como el derecho aplicable y el reconocimiento y la ejecución de sentencias. Con base en estas disposiciones, se analizará la declaración de herederos adoptada por un tribunal alemán en el caso de una mexicana que fallece en Alemania, dejando bienes en Alemania y en México, y en el caso inverso. Se cuestionará, además, si estas resoluciones pueden ser reconocidas en México con respecto a bienes ubicados en ese país. En el primer caso, el tribunal aplicará el derecho alemán a toda la sucesión; en el segundo, en cambio, la sucesión será fragmentada, aplicándose a los bienes ubicados en México el derecho de este Estado, mientras que, con respecto a los bienes ubicados en Alemania, se aceptaría el reenvío parcial al derecho alemán...
The role of naming in healthcare. From a psychiatric hospital to a mental health center
Authors:   Bekhterev Psychoneurological Research Institute, Neznanov N.G. , Kochorova L.V. ,   I.P. Pavlov First St. Petersburg State Medical University, Skripov V.S. ,   Bekhterev Psychoneurological Research Institute,   I.P. Pavlov First St. Petersburg State Medical University, Nabatov I.F. ,   Center of Psychiatry and Mental Health Academician V.M. Bekhterev, Martovetskaya G.A. ,   Center of Psychiatry and Mental Health Academician V.M. Bekhterev
Published: January 2023

An urgent issue today is to increase the confidence of citizens in the healthcare system. Moreover, the issue of trust is of particular importance in the provision of psychiatric care, due to the high level of stigmatization of this area of medicine. The purpose of the study was to assess the significance for patients of the names of medical organizations in the profile of «psychiatry». Materials and methods. In 2021 Kirov Regional Clinical Psychiatric Hospital named after Academician V.M. Bekhterev changed its name and became the Center for Psychiatry and Mental Health Academician V.M. Bekhterev. A survey was conducted of 216 patients who applied or are undergoing treatment at the Center of Psychiatry and Mental Health named after Academician V.M. Bekhterev, using a specially designed questionnaire consisting of 24 questions. The results obtained were statistically processed. Results. A large proportion of the respondents had one or another mental disorder, and more than half are worried because of this, to one degree or another. One-fifth of the respondents indicate that their rights were violated due to their mental disorders. All this points to the problems that exist to this day associated with the stigmatization of patients with mental disorders, as well as the stigmatization of the psychiatric service itself. 43% of respondents noted that the name of a medical organization has an impact on their trust in a medical organization. The patients surveyed gave the highest rating to the name «Mental Health Center». Conclusions. Thus, the name of a medical organization directly affects the trust of patients in it. In addition, the name also affects the subjective assessment of the quality of medical care provided in a medical organization.
Intentional potential of scientific and clinical heads as a strategic resource of a healthcare organization
Authors:   N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Petrikov S. S. , Tsaranov K. N. ,   Moscow Metropolitan Governance Yury Luzhkov University, Zavaliy L. B. ,   N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Tarbastaev A. G. ,   N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Kanibolotsky A. A. ,   N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Tsuleiskiry B. T. ,   N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department
Published: January 2023

R e l e v a n c e . The healthcare management system requires high-quality and rational use of the organization’s workforce, i. e. the skills of employees. The intentional potential of an employee is a set of needs, motives, etc., the «core» of the personality driving it to achieve a meaningful goal. The N. V. Sklifosovsky Research Institute for Emergency Medicine is a leading multidisciplinary medical institution with an established multi-level system and management culture, the quantitative assessment of the intentional potential of which is of great interest. P u r p o s e : to study the intentional potential of the heads of clinical and scientific departments. M e t h o d s . An anonymous survey was conducted among the heads of the scientific and clinical departments of the N. V. Sklifosovsky Research Institute for Emergency Medicine (2021), including two methods of S. Schwartz: assessment by the level of normative ideals (SVS) and by individual priorities (PVQ). The procedures of centering and ranking by the average values of each valuemotivational type were carried out. Next, the value-intentional consistency (VIC) and the coefficient of value oppositions (Cvo) were investigated. F i n d i n g s . No statistically significant differences in the VIC at the SVS and PVQ levels, as well as no differences in the Cvo at the SVS level in the groups of heads of clinical and scientific departments were revealed. Intrapersonal contradictions between the value oppositions «Security» and «Stimulation» at the PVQ level (p<0.05) were revealed, they are less pronounced in the group of heads of scientific departments. There were also no statistically significant differences in the other oppositions of value orientations of the PVQ level. C o n c l u s i o n s . The presented results can be used as additional factors in the planning and implementation of measures of sociopsychological management of scientific and clinical departments. In the professional selection for the relevant positions, the Cvo indicator is more informative. Differences between the groups of scientific and clinical heads in the «Security – Stimulation» Cvo were shown, the distribution of this indicator tends to be more pronounced among the group of scientific heads.
Assessment of Esophageal Reconstruction via Bioreactor Cultivation of a Synthetic Scaffold in a Canine Model
Authors: Kim In Gul , Wu Yanru , Park Su A , Choi Ji Suk , Kwon Seong Keun , Choi Seung Hong , Jung Kyeong Cheon , Shin Jung-Woog , Chung Eun-Jae
Published: January 2023

Objectives. Using tissue-engineered materials for esophageal reconstruction is a technically challenging task in animals that requires bioreactor training to enhance cellular reactivity. There have been many attempts at esophageal tissue engineering, but the success rate has been limited due to difficulty in initial epithelialization in the special environment of peristalsis. The purpose of this study was to evaluate the potential of an artificial esophagus that can enhance the regeneration of esophageal mucosa and muscle through the optimal combination of a double-layered polymeric scaffold and a custom-designed mesenchymal stem cell-based bioreactor system in a canine model.Methods. We fabricated a novel double-layered scaffold as a tissue-engineered esophagus using an electrospinning technique. Prior to transplantation, human-derived mesenchymal stem cells were seeded into the lumen of the scaffold, and bioreactor cultivation was performed to enhance cellular reactivity. After 3 days of cultivation using the bioreactor system, tissue-engineered artificial esophagus was transplanted into a partial esophageal defect (5×3 cm-long resection) in a canine model.Results. Scanning electron microscopy (SEM) showed that the electrospun fibers in a tubular scaffold were randomly and circumferentially located toward the inner and outer surfaces. Complete recovery of the esophageal mucosa was confirmed by endoscopic analysis and SEM. Esophagogastroduodenoscopy and computed tomography also showed that there were no signs of leakage or stricture and that there was a normal lumen with complete epithelialization. Significant regeneration of the mucosal layer was observed by keratin-5 immunostaining. Alpha-smooth muscle actin immunostaining showed significantly greater esophageal muscle regeneration at 12 months than at 6 months.Conclusion. Custom-designed bioreactor cultured electrospun polyurethane scaffolds can be a promising approach for esophageal tissue engineering.
Potencialidad del aviturismo para el desarrollo de iniciativas comunitarias en Cumaral Meta (Colombia)
Authors: MORA FORERO JORGE ALEXANDER , RAMÍREZ GARCÍA NORMA ALEJANDRA
Published: January 2023

ResumenActualmente Colombia es reconocido como uno de los países de mayor diversidad de aves en el Mundo, lo cual representa una oportunidad para el desarrollo de actividades turísticas en torno a la observación de estas especies. El presente artículo pretende determinar el potencial aviturístico de Cumaral Meta, a partir del diagnóstico y análisis de la oferta y la demanda con posibilidades de conformación de un producto turístico de avistamiento de aves. Asimismo, se ha analizado la potencialidad que tiene el municipio para la actividad turística de avistamiento de aves teniendo en cuenta el perfil de la demanda turística. Para ello se han realizado entrevistas y encuestas a los turistas que visitan este municipio. En segundo lugar, se ha realizado un inventario de aves que ha evidenciado la gran biodiversidad que posee Cumaral en materia ornitológica. Y finalmente se han identificado aquellas acciones que se requieren para la implementación de un producto turístico acorde con la oferta y la demanda real y potencial. Palabras clave: Aviturismo; desarrollo rural; producto turístico; turismo comunitario. AbstractCurrently Colombia is recognized as the country with the greatest diversity of birds in the world, which represents an opportunity for the development of tourist activities around the observation of these species. This article aims to determine the potential of avitourism of Cumaral Meta, from the determination of supply and demand to propose a tourism product of bird watching in the area. To do this, the potential of the municipality for the tourist activity of bird sighting was analyzed, considering the profile of tourism demand. This was achieved through interviews and surveys, to tourists visiting this municipality. Secondly, an inventory of birds is carried out, which shows the great biodiversity that Cumaral has in ornithological matters. Finally, the elements required for the implementation of a tourism product according to supply and demand are proposed, according to the results of this research. Keywords: Birdwatching; rural development, tourist product, community tourism.
Gastronomy: a customer study of restaurant in Cordoba (Spain) included in a prestigious guide
Authors: HERNÁNDEZ ROJAS RICARDO DAVID , BALDERAS-CEJUDO MARÍA ADELA , ALONSO SOBRADO DUNIA
Published: January 2023

Abstract

Culinary tourism based on visiting restaurants and tasting dishes where a strong link and identity exist with the destination is increasingly becoming an opportunity to attract tourists. Visiting a fine-dining restaurant is one of the features of culinary tourism and it also leads to greater dissemination of the historical and cultural heritage of the region. Therefore, this paper seeks to learn more about the so-called gastronomic tourist who visits a prestigious restaurant attracted by the information in gastronomic guides or ratings of the chef working there. The field work was conducted at the ReComiendo Restaurant in Cordoba, when the motivations and satisfaction of the customers who visit this type of establishment were studied.

The analysis shows that developing culinary tourism based on visiting a well-known establishment influences the perception of the culture of the area. Therefore, increasing and enhancing the number of visitors at a culinary destination will, to a large extent, depend on the local culinary heritage being featured at its restaurants, the updating of its offer, a tasting menu based on a common thread, together with the updating of traditional gastronomy using cutting-edge techniques.

Key words: culinary tourism, gastronomy, gastronomic guides, gastronomic experiences, Cordoba (Spain).

 

Resumen

El turismo culinario basado en visitar restaurantes y probar platos que mantienen un fuerte vínculo e identidad con las tradiciones culturales del destino, se está convirtiendo cada vez más en una oportunidad para atraer turistas. Visitar un restaurante de alta cocina es una de las características del turismo culinario y también conduce a una mayor difusión del patrimonio histórico y cultural de la región visitada. Por lo tanto, este trabajo busca aprender más sobre el llamado turista gastronómico que visita un prestigioso restaurante atraído por la información existente en las guías gastronómicas o las calificaciones del chef que trabaja allí. El trabajo de campo se realizó en el restaurante “ReComiendo” de Córdoba, donde se estudiaron las motivaciones y la satisfacción de los clientes que visitan este tipo de establecimientos.

El análisis muestra que el desarrollo del turismo culinario basado en la visita a un establecimiento conocido influye en la percepción de la cultura y la oferta turística de la zona. Por lo tanto, aumentar y mejorar el número de visitantes en un destino culinario dependerá, en gran medida, del patrimonio culinario local que se presenta en sus restaurantes, la actualización de su oferta, un menú de degustación basado en un hilo común, junto con la innovación de la gastronomía tradicional utilizando técnicas de vanguardia.

Palabras clave: turismo gastronómico, gastronomía, guías gastronómicas, experiencias gastronómicas, Córdoba (España).
Propuesta metodológica de diagnóstico de los sistemas de distribución comercial en las agencias de viajes
Authors: GONZÁLEZ PERAZA BRENDA DE LA CARIDAD , HERNÁNDEZ FLORES YOAN , RODRIGUEZ GONZÁLEZ MAITÉ
Published: January 2023

En un contexto donde la crisis impuesta por la Covid-19 ha generado profundos cambios en las dinámicas del sector turístico, a las agencias de viajes les urge la toma de decisiones estratégicas respecto a los canales de distribución a emplear. Para ello, resulta imprescindible la evaluación oportuna de sus sistemas de distribución mediante una metodología de diagnóstico coherente y eficaz. La presente investigación se orienta en el estudio minucioso de varios modelos de diagnóstico dediverso tipo, para, en consecuencia, proponer un procedimiento metodológico aplicable a los sistemas de distribución de las agencias de viajes en un escenario postcoronavirus. Con dicho propósito, se emplearon métodos empíricos y teóricos, que permitieron realizar un análisis integral de dicha cuestión. Los resultados posibilitaron la obtención de un modelo de diagnóstico, que incluye procedimientos de diagnóstico estratégico del estado de la gestión de la distribución comercial, cuya aplicación en las agencias de viajes ayudará en la definición de problemas, expondrá los puntos álgidos y generará los resultados base para plantear las acciones estratégicas correspondientes.

Palabras clave: agencia de viajes, distribución comercial, modelos de diagnóstico.
El papel informativo y promocional de las comunidades virtuales: el caso de los establecimientos hoteleros en Agadir (Marruecos)
Authors: FAOUZI HASSAN
Published: January 2023

En muchas partes del mundo los viajeros tienen un interés especial en la acogida y la calidad de los establecimientos de alojamiento de los países visitados, convirtiéndose en uno de los principales pilares de la promoción turística (marketing turístico). Los nuevos turistas participan activamente en el mecanismo de marketing mediante la difusión de sus opiniones vía foros virtuales o guías de viaje (Guía Michelin, El Mochilero, Lonely Planet, TripAdvisor), que permiten a los usuarios de internet informar y dar testimonio de sus experiencias y debatir sobre esto. Así, los foros virtuales son los primeros en dar cuenta de las nuevas tendencias y representan una garantía de una información de calidad al medir el grado de satisfacción manifestado por los turistas en relación con su estancia. Nuestra investigación aborda la mirada crítica que los visitantes extranjeros tienen sobre la acogida y la calidad en los establecimientos de alojamiento turístico en Agadir (Marruecos) y esto a través de la lectura y el análisis de los comentarios, las opiniones y las evaluaciones, expresadas por las comunidades virtuales de viajeros de TripAdvisor, respecto de las prestaciones de las estructuras hoteleras en Agadir.

Palabras clave : TripAdvisor, comunidades virtuales, establecimientos hoteleros, promoción turística, Agadir, Marruecos
El patrimonio arquitectónico en la Andalucía rural: estado de la cuestión y factores clave para su recuperación a través de nuevos modelos turísticos
Authors: ROMERO CAÑABATE ELENA , RAMÍREZ  PACHECO GEMA MARÍA
Published: January 2023

La arquitectura vernácula en el campo andaluz se presenta como un conjunto de espacios en decadencia y, en múltiples casos, en riesgo de desaparición. Sin embargo, son focos de oportunidad que precisan de un proceso de reconversión que garantice su recuperación y puesta en valor. El objetivo principal de este trabajo es identificar estrategias para la recuperación social, ambiental y cultural del medio rural andaluz. Dentro de este contexto se plantea el turismo rural como una herramienta válida para la puesta en valor del patrimonio existente, exponiendo la repercusión que tiene en Andalucía, y su incidencia en el patrimonio arquitectónico vernáculo que se encuentra diseminado en dicho medio. La pregunta abordada es la posibilidad de utilizar un modelo turístico sostenible y respetuoso como herramienta para garantizar la viabilidad económica de la recuperación y puesta en valor del patrimonio rural andaluz. A través de un recorrido desde inicios del siglo XX hasta la actualidad, planteando la relación de esta problemática con el marco normativo urbanístico y turístico, tanto a nivel autonómico como estatal y europeo, se exponen las convergencias y divergencias existentes, que suponen un punto de inflexión en la generación de oportunidades. El trabajo pone de relieve diferentes factores que definen el turismo rural, generalmente abordados de forma aislada, pero que tienen implicaciones y conexiones que obligan a tratarlo de forma global. De esta manera, se espera abrir nuevas perspectivas con un carácter movilizador y propositivo, que faciliten y ayuden a la dinamización de este tipo de intervenciones necesarias para la supervivencia del patrimonio arquitectónico rural andaluz.

Palabras clave: turismo; patrimonio; arquitectura vernácula; marco normativo; Andalucía.
Tendencias en la comercialización digital de las agencias de viajes en en el escenario del COVID-19
Authors: HERNÁNDEZ FLORES YOAN , SALGADO DOMÍNGUEZ EMILY , MOREJÓN SÁNCHEZ PATRICIA
Published: January 2023

El sector del turismo atravesó por una crisis sin precedentes a nivel global durante el año 2020 como consecuencia de la pandemia provocada por el virus Sars-CoV-2, lo que ha obligado a todos los actores públicos y privados de la cadena de valor turística a concentrar sus esfuerzos en superar la crisis. En este sentido, resulta indispensable que las agencias de viajes realicen estudios para reformular sus metas y modos de actuación en una posible etapa de recuperación. En un entorno caracterizado por tendencias diferenciadas, resulta necesario que los procesos de marketing busquen satisfacer las verdaderas necesidades de los clientes desde todas sus posibles perspectivas. Por lo que el presente trabajo propone determinar las mejores prácticas en cuanto a la comercialización digital de los productos de las agencias de viajes en tiempos de COVID-19. Para ello se propuso realizar un estudio tomando en cuenta la gestión de diferentes agencias tradicionales que hayan adaptado sus modelos de negocios al nuevo escenario tecnológico. Finalmente se identificaron diferentes tendencias como la automatización del marketing, el uso del inbound marketing, el uso de las herramientas Search Engine Optimization y Social Media Marketing, así como el empleo de la Inteligencia Artificial y el Big Data para una mejor atención al cliente en las agencias de viajes.

Palabras clave: Agencias de viajes; comercialización digital; COVID-19; tendencias.
Desarrollo turístico y calidad de vida en el “Pueblo Mágico” de San Sebastián del Oeste (Jalisco, México): un análisis desde la percepción de los ciudadanos
Authors: MÁRQUEZ GONZÁLEZ ANTONIO ROMUALDO , ESPINOZA SÁNCHEZ RODRIGO , VERDUZCO VILLASEÑOR MARÍA DEL CARMEN
Published: January 2023

El desarrollo turístico en los municipios rurales de México ha sido impulsado recientemente por nuevas políticas gubernamentales que buscan encontrar acciones estratégicas para resolver problemas inherentes a la pobreza y marginación de sus poblaciones. Estas condiciones de precariedad impiden en ocasiones tener una visión y entendimiento enfocados a la conservación de los recursos naturales y culturales existentes en estos territorios. Ante esta perspectiva, algunas comunidades que reunieron las características requeridas para solicitar la denominación o insignia de “Pueblo Mágico· (PM) en México, se aventuraron a impulsar y promover el desarrollo del turismo bajo la arista de la conservación del patrimonio existente y así fortalecer la dinámica eco-socioeconómica, persiguiendo acortar, al mismo tiempo, las asimetrías existentes en el tejido social. El objetivo del presente trabajo es mostrar resultados de investigación cualitativa soportados en una entrevista estructurada aplicada a una población abierta, para conocer cómo ha impactado la denominación PM en el territorio. Los principales resultados encontrados muestran que sus habitantes perciben avances en la mejora de la calidad de vida de la población y consideran además que el pueblo con el turismo, su infraestructura y los servicios públicos muestran mejoras sensibles. Como conclusión general, se puede señalar que el refrendo de la denominación PM de San Sebastián del Oeste ha impactado en la calidad de vida de la población del lugar.

Palabras clave: Desarrollo Turístico, Desarrollo Local, Pueblo Mágico, Calidad de Vida, Jalisco, México.
Un análisis desagregado del impacto de la pandemia sobre las pernoctaciones turísticas en España
Authors: BENÍTEZ-AURIOLES BEATRIZ
Published: January 2023

Las afirmaciones genéricas sobre los efectos que ha provocado la pandemia de la COVID-19 sobre el turismo ocultan realidades muy diversas. El objetivo de este trabajo es realizar un análisis desagregado del impacto que ha tenido la pandemia en las pernoctaciones turísticas en España, considerando la estructura de la demanda por tipos de alojamiento a nivel regional. Planteamos la hipótesis de que dicho impacto ha sido más intenso en los hoteles, donde resulta más difícil mantener la distancia social, y que, en consecuencia, dependiendo de la especialización de cada región en un determinado segmento de la demanda turística, el impacto territorial ha sido, asimismo, diferente. Se aplica un análisis shift-share para los años 2019 y 2021, con datos de pernoctaciones en hoteles, apartamentos turísticos, alojamientos rurales, campings y albergues, de las Comunidades Autónomas. Los resultados confirman que las pernoctaciones que descendieron en mayor medida fueron las realizadas en los hoteles y apartamentos turísticos y que, sobre esa base, la pandemia tuvo un impacto territorial claramente diferenciado. Aunque con las lógicas matizaciones, cabría afirmar que las regiones especializadas en turismo rural o relacionado con la naturaleza han experimentado una reducción menos acusada de la demanda turística.

Palabras clave: COVID-19; demanda turística; análisis shift-share; regiones españolas
Turismo y tecnologías en territorios complejos. El caso del Qhapaq Ñan en el Desierto de Atacama (Chile)
Authors: MUÑOZ BASCUÑÁN ALAN
Published: January 2023

Como parte del desarrollo de una iniciativa de innovación y competitividad para la región de Atacama, Chile, se desprende este estudio que buscó evaluar la viabilidad de generar experiencias turísticas con tecnologías de georreferenciación, realidad aumentada y recursos audiovisuales, en el territorio que abarca el Qhapaq Ñan o Camino del Inca en esta región. Este patrimonio de la humanidad reúne un conjunto de recursos arqueológicos y sitios patrimoniales extendidos en distintas áreas del desierto, donde las complejas condiciones naturales de su geografía pueden ser limitantes para el desarrollo de actividades como el turismo. Los resultados revelan que es posible desarrollar experiencias turísticas basadas en el patrimonio arqueológico, con el apoyo de tecnologías adecuadas a las condiciones mencionadas, y que el rol de los actores sociales es clave tanto para el desarrollo del turismo, como para la adecuación de las tecnologías a las condiciones reales en que serán utilizadas en este complejo lugar.

Palabras clave: Experiencias turísticas, Tecnologías. Qhapaq Ñan, Atacama, patrimonio.
Transición digital y reajuste del sector turístico en la Unión Europea
Authors: SANCHEZ-BAYON ANTONIO
Published: January 2023

Revisión heterodoxa de Economía Política y Macroeconomía sobre el efecto reajuste en el sector turístico por impacto de la transición digital y su agravamiento con las crisis COVID-19 y guerra en Ucrania. Se plantea una síntesis del cambio paradigmático con la economía digital y cómo afecta a las relaciones laborales y profesionales, requiriéndose de una transformación del sistema económico y el proceso productivo. Se centra la atención en el sector turístico y su paradoja en la Unión Europea: pese a su creciente importancia, en cambio, su reconocimiento y transformación resulta insuficiente. Dicha paradoja se intensifica en el caso español, donde más fondos europeos de recuperación se están destinando y sin embargo está creciendo la vulnerabilidad de sus PYMES y emprendedores turísticos.

Palabras clave: transición digital; efecto reajuste; turismo; Unión Europea (UE); crisis; PYMES; emprendedores; Nueva Economía Política.
Compositional analysis of live fish import trade in India
Authors: C. G. Joshy  , A. Suresh  , Panda S. K. , C. N. Ravishankar
Published: January 2023

The live fish import trade in India under the harmonised system (HS) code 0301 (HS-0301) increased exponentially in terms of import quantity and value during the period 2000-2019. India imported 1.32 t of live fish worth US $ 0.017 million in 2000, which increased to 653.27 t worth US $ 3.21 million in 2019. The import of both marine as well as freshwater ornamental fish was found to increase during the period 2013-2019. The major countries exporting marine and freshwater ornamental fish to India were Thailand, Indonesia, Malaysia, Singapore and Sri Lanka. The import of live trout and carp to India was found to be very less during the period 2000-2019. The majority of live fish import to India accounted in the subclass HS030199 since 2017, with 81.55, 91.86 and 74.03% of total live fish imported to India in 2017, 2018 and 2019, respectively. Bangladesh accounted 81.02, 87.84 and 83.11% of total import quantity and 0.74, 82.42 and 49.51% of total import value under the sub-head HS-030199 during 2017, 2018 and 2019, respectively. While import of live fish offers economic opportunities, it has the potential to bring biosecurity threats including fish pathogens to Indian waters. The economic trade-off is to be evaluated on a case to case basis supported with legal and institutional back-up. Enacting a comprehensive legal framework and creating quarantine facilities are critical in this direction. Keywords: Compositional analysis, HS-0301, Import, Ornamental fish, , Trade balance
Biometric evaluation of Gangetic pool barb Puntius sophore (Hamilton, 1822) from the River Ganga, Bihar, India
Authors: Ahirwal S. K. , Singh Jaspreet , Kumar Tarkeshwar , Bharti Vivekanand , Sarma Kamal , Narayan Deva
Published: January 2023

The Gangetic pool barb Puntius sophore (Hamilton, 1822) is widely distributed in the freshwater ecosystems of the Indian subcontinent and it is reasonably well-priced due to its nutritional value. A study was conducted to assess the morphometry, length-frequency distribution (LFD), length-weight relationship (LWR), condition factor (CF) and sex ratio of P. sophore collected from the Digha GhatPatipul in Patna, between March 2019 and February 2020. Fifteen morphometric characters and nine meristic counts of 137 specimens were examined for biometric evaluation and 982 samples (1.56-22.09 g TW, 51.06-115.11 mm TL) were analysed for LFD, LWR and CF, respectively. LFD revealed that 28.49% of the males sampled were in the 75-80 mm length class, while 15.94% of the total females sampled were in the 70-75 mm length class. In morphometric analysis, significant correlations were found across the variables and the highest correlation was observed between total length and standard length (r>0.981). LWR exponent value showed positive allometric growth patterns for male, female, and combined sexes, respectively. Condition factor showed no significant variation between the sexes and the observed average values were 1.06 and 1.24 for males and females, respectively (p<0.05). Analysis of the sex ratio showed that females outnumbered males from the 85-90 mm length group onwards and no male specimens were found beyond the 105-110 mm length group.Keywords: Condition factor, Length-weight relationship, Morphometry, P. sophore, Sex ratio
Relative abundance of yellowfin tuna Thunnus albacares (Bonnaterre, 1788) in the tropical area of the north-eastern Indian Ocean
Authors: Setyadji Bram , Hartaty Hety
Published: January 2023

The tropical area of the north-eastern Indian Ocean has historically been a prominent fishing ground for yellowfin tunaThunnus albacares (Bonnaterre, 1788). However, low effort from either Japanese or Taiwanese fleet in the last two decadeshas driven some uncertainties in relative abundance estimates of yellowfin tuna, which affects the robustness of the currentstock analysis for an already declined population. Hence this study was carried out to bridge the research gap by utilising theIndonesian scientific observer data from 2006-2021, which covers the north-eastern Indian Ocean. A delta-lognormal modelwas adopted to fit the data, with the catch per unit effort as the response variable and year, quarter, moon phase, latitudeand longitude as known covariates. The optimal model was chosen using a backward method based on Akaike InformationCriterion (AIC) (Akaike, 1974), Bayesian Information Criterion (BIC) (Schwarz, 1978) and the values of the coefficientof determination (R2). In general, the relative abundance of yellowfin tuna remained at a very low level, with an apparentdeclining trend in the first decade, followed by a slight sign of recovery in the past three years. However, the increasing trendwas overshadowed by uncertainties, likely caused due to natural variation and low coverage in some years. Although theseries was considered short, it managed to picture the dynamics of the abundance of yellowfin tuna in the tropical area of thenorth-eastern Indian Ocean, which is essential for conducting a more robust harvest strategy evaluation.
Keywords: Declining stock, Fisheries-independent data, Highly migratory, Relative abundance, Scientific observer
Paleoproterozoic Shoshonite Mafic Associations of the Irkut Block (Sharyzhalgai Uplift, Southwest Siberian Craton): U–Pb Age and Conditions of Zircon Crystallization
Authors: Turkina O.M. , Sukhorukov V.P. , Rodionov N.V.
Published: January 2023

—The paper presents data on the composition and age of mafic rocks of the shoshonitic series in the Irkut block of the Sharyzhalgai uplift (southwest of the Siberian Сraton). According to the U–Pb dating of magmatic zircon, the formation of monzodiorites of the Poludennyi massif and gabbro-dolerites in the endo- and exocontact zones of the Toisuk pluton occurred at 1.87 and 1.86–1.85 Ga, respectively. The intrusion of mafic magmas and their underplating into the basement of the crust under postcollisional extension resulted in the near-coeval mafic and granitoid magmatism in the Irkut block between 1.87 and 1.84 Ga. The Paleoproterozoic mafic associations belong to the shoshonitic series and are characterized by enrichment in incompatible elements, including Zr, and low negative εNd(T) values. These geochemical and isotopic characteristics point to the derivation of magma from a long-lived enriched-mantle source, such as the subcontinental lithospheric mantle. The crystallization of zircon from the last portions of the evolved mafic melt is evidenced by low zirconium saturation temperatures (710–965 °C) and zircon enrichment in U and Th with increasing Th/U, reflecting the growth of concentrations of highly incompatible elements in the residual melt.
M.Yu. Lermontov’s Mysterious Religiosity
Authors:   Institute of Philosophy, St. Petersburg State University, Evlampiev Igor I.
Published: January 2023

The article reveals the characteristic features of the religious and philosophical worldview of M.Yu. Lermontov, first discovered by Russian thinkers of the Silver Age. Lermontov thinks that the divine principle of being lies in man and represents his deepest essence. A person who has managed to reveal his human essence to the fullest extent becomes a “higher personality”, a divine being with extraordinary power in relation to the world around him. The article shows that the main character of the novel “A Hero of Our Time” Pechorin is such a “higher personality”, he is able to rule over fate and over ordinary people. The special nature of Pechorin’s re­lationship with fate is clearly shown by Lermontov in the last part of the novel, called “The Fatalist”. A detailed analysis of this part of the novel allows us to assert that the dispute between Pechorin and the Serb Vulich essentially expresses the struggle of the wills of two heroes. It is Pechorin, as a more developed “higher personality”, with his will, with his almost divine power, who determines the fate of Vulich and directs him to inevitable death. The article shows that the idea of a person that is present in the novel “A Hero of Our Time” can be found in the story of A.S. Pushkin “The Queen of Spades”; later it becomes the basis of philosophical outlook of F.M. Dostoevsky. Like Lermontov, Dostoevsky believes that God is nothing but the true essence of man, and for the will of a person who has fully re­vealed his essence, there are no restrictions in the world.
The Theoretical Complexes in the Cognitive Sciences
Authors:   Institute of Scientific Information for Social Sciences of the Russian Academy of Sciences, Sushchin Mikhail A.
Published: January 2023

In this work, the author further develops the idea of theoretical complexes, which has been earlier proposed for the sake of description of large theoretical movements in the cognitive sciences, such as classical computational cogni­tivism, connectionism or moderate embodied cognition. It is asserted that the lat­ter should be understood as structurally homogeneous or heterogeneous theoreti­cal complexes, which function primarily for further proliferation of scientific theories and models. It is argued that the idea of theoretical complexes is more ad­equate for the task of description of large groups of theories in the cognitive sci­ences when compared with alternative theories of T. Kuhn, I. Lakatos, L. Laudan, and B. von Eckardt. In the second part of the work, in the context of the defense of theoretical pluralism in the philosophy of science we attempt to draw the main methodological normative conclusions of the idea of theoretical complexes in the cognitive sciences. The key role here is given to the principle of prolifera­tion, which calls for the creation of scientific theories and models which are both compatible and incompatible with respect to a number of basic ontological and methodological assumptions. In conclusion, we briefly discuss the character and limitations of the proposed principle of proliferation.
Alfred Schnittke’s “Faust Cantata” and Philosophy of Polystylism
Authors:   Institute of Russian Studies, Hankuk University of Foreign Studies, Lee Ji Yeon
Published: January 2023

For Alfred Schnittke (1934–1998), a representative of the Soviet musical avant-garde, the story of Faust was a life-defining text. A particularly important role in his biography was played by the novel Doctor Faustus by Thomas Mann, which became a kind of encyclopedia of the composer’s life and works. Mann’s novel reflects his philosophy of music, which was greatly influenced by Theodor Adorno’s reflections on modern music. Schnittke considered Mann’s main char­acter Leverkuhn to be his musical alter ego and throughout his life followed the musical pursuits of this fictional composer. This article describes in parallel the musical evolution of Leverkuhn and Schnittke. The Soviet composer has re­alized in his life Leverkuhn’s musical pursuits: the important elements in the de­velopment of Schnittke’s music, such as serialism, monogram and polystylism, were a reflection of Leverkuhn’s musical experiments in the novel. The author of this article, analyzing the peculiarity of genre and musical, as well as meta-musical structure of Schnittke’s Faust Cantata, explains the composer’s polystylism as a polyphony and also investigates his philosophy of music. For Schnittke, mu­sic was not so much an imitation of natural sounds, an expression of human feel­ings and emotions, or a representation of absolute harmony, as a kind of semiotic system within which there happens a free dialogue between musical forms, meta-musical reflections on musical languages, intellectual plays with abundant musical material. The pinnacle of Schnittke’s musical evolution Faust Cantata was a realization of his philosophy of music as a polyphony not only in art, but also in life.
Forecasting of Express Delivery Volume Based on the Lasso-BP-GM-MLR Model
Authors: zhang tianxian , Yang Lijuan , Xia Mengjue , Zhu Zan , Cao Zhibin
Published: January 2023

With the development of the Internet and e-commerce, the express delivery volume is growing rapidly，and the accurate prediction of express delivery volume is of great significance to the planning of the express industry.This paper proposes a new method for predicting express delivery volume—Lasso-BP-GM-MLR model. Firstly, the Lasso method is used to filter the input parameters of BP neural network and construct lasso-BP network.Then the Lasso-BP-GM-MLR model is constructed by combining the advantages of the Lasso-BP network, GM (1, 1) and MLR (multiple linear regression) models. Finally, the case analysis of China's express delivery volume shows that the Lasso-BP model has better prediction effect than BP, Lasso-RBF and Lasso-GRNN models, while the Lasso-BP-GM-MLR model has higher accuracy than the Lasso-BP network, GM (1, 1) and MLR models.
Reliability Redundancy Allocation for Fire Extinguisher Drone using Hybrid PSO-GWO
Authors: Bhandari Ashok Singh , Kumar Akshay , Ram Mangey
Published: January 2023

Reliability Redundancy Allocation Problem (RRAP) plays a vital role in reliability improvement and designing of any system which depends on the arrangement of components i.e., series, parallel, or complex, reliability of the components, and redundancy allocation for the components. In this work, a Fire Extinguisher Drone (FED) is considered for RRAP. The FEDs are very valuable for firefighters in tackling emergencies in non-reachable areas. To maximize the reliability of FED a non-linear mixed integer programming problem is formulated and optimized using the Hybrid Particle Swarm Grey Wolf Optimizer (HPSGWO). This metaheuristic fuses the Particle Swarm Optimization’s (PSO) exploitation ability with the grey wolf optimizer’s (GWO) exploration ability. With constraints such as cost, weight, and volume for the system, different levels of redundancies are applied to get the best redundancy allocation that maximizes the reliability of FED. Also, the results are of HPSGWO for each allocation are compared with the results of GWO, which clearly explains the superiority of the HPSGWO over GWO as well as PSO.
10-Year Outcomes of Concomitant Boost Irradiation Following Breast-conserving Surgery versus Sequential Boost for Early-stage Breast Cancer treatment
Authors: Chen Zhongjie , Wang Wei , Yan Bo , Li Jing , Zhu Li , Yuan Zhiyong , Ning Wen , Wang Ping
Published: January 2023

Background: Concomitant boost irradiation (CB) in adjuvant whole breast radiotherapy (WBI) is increasingly prevalent. Multiple studies have reported the effect of CB; however, long-term outcomes after CB remain unknown.
Methods: Totally 266 patients administered breast-conserving surgery from March 2007 to November 2012 were included in this retrospective analysis. They were administered WBI at 45 Gy (range, 43.2-46) in 23 fractions (range, 18-25). CB irradiation was delivered shortly after WBI completion with 9 or 12 Mevβ electrons at a dose of 13.8 Gy (range, 7.2-15) in 23 fractions (range, 18-25). Sequential boost irradiation (SB) was conducted sequentially after the entire WBI treatment at a dose of 14 Gy (range, 10-15) in 7 fractions (range, 4-8). Then, 10-year survival, local control, and toxicity in these two groups were analyzed.
Results: Median follow-up time was 124 months, ranging from 121.6 to 126.4. The 10-year disease-free (DFS) and overall (OS) survival rates were similar in both groups, both before and after PSM. Both distant metastasis and recurrence rates in the CB group were similar to those of the SB group after PSM. Moreover, both groups had similar cosmetic outcomes and radiation-associated late toxicity.
Conclusions: Survival, local tumor control, cosmetic outcome, and late toxicity were comparable in the CB and SB groups. WBI with CB can be considered an effective therapeutic tool in early-stage breast cancer.
A novel de novo nonsense mutation in SALL4 causing duane radial ray syndrome: A case report and expanding the phenotypic spectrum
Authors: Ajam-Hosseini Mobarakeh , Parvini Farshid , Angaji Abdolhamid
Published: January 2023

Background: SALL4, a member of the SALL genes family, encodes a zinc-finger transcriptional factor that either activates or represses gene transcription depending on cell type during embryonic development. SALL4 mutations cause extremely variable conditions including Duane-radial ray (DRR), Okihiro, Holt-oram, Acro-renal ocular (ARO) and IVIC syndromes, all with autosomal dominant inheritance pattern. However, all these syndromes with different terminologies are actually the same entity termed SALL4 related disorders.
Case presentation: Herein, we examine an Iranian patient suspected to DRR syndrome which has not been previously described in the population. Whole-exome sequencing (WES) was performed to examine pathogenic genes in the proband. Subsequently, Sanger sequencing was used to confirm the mutation found. To elucidate the effects of the identified mutation, clinical data of patient was collected. Morever, the possible impact of the mutation found on the corresponding protein was evaluated using bioinformatics tools. WES identifed a novel de novo heterozygous nonsense mutation in exon 2 of SALL4 gene (c.712C>T:p.Q238X). Subsequently, segregation and phenotype-genotype correlation analysis as well as in-silicoapproaches confirmed the autosomal dominance inheritance and disease-causing nature of the identified mutation. In addition, studied patient had features not described previously, including kyphoscoliosis, dimple presacral sinus, barrel chest and artric disc (C6-C7). These manifestations could be additional characteristics of the growing phenotypic spectrum of SALL4 related disorders.
Conclusion: Our findings could extend the pathogenic mutations and phenotypic spectrum of SALL4 related disorders. Such reports can also aid to conduct genetic counseling, prenatal diagnosis and clinical management for individuals at high risk of SALL4 related disorders.
Structure and dynamics of the EGFR/HER2 heterodimer
Authors: Zhang Zhe , Bai Xue , Sun Pengyu , Wang Xinghao , Long Changkun , Liao Shuyun , Dang Song , Zhuang Shangshang , Du Yongtao , Zhang Xinyi , Li Nan , He Kangmin
Published: January 2023

HER2 belongs to the human epidermal growth factor receptor tyrosine kinase family. Its overexpression or hyperactivation is a leading cause for multiple types of cancers. HER2 functions mainly through dimerization with other family members, such as EGFR. However, the molecular details for heterodimer assembly have not been completely understood. Here, we report cryo-EM structures of the EGF- and epiregulin-bound EGFR/HER2 ectodomain complexes at 3.3-Å and 4.5-Å resolution. Together with the functional analyses, we demonstrate that only the dimerization arm of HER2, but not that of EGFR, is essential for their heterodimer formation and signal transduction. Moreover, we analyze the differential membrane dynamics and transient interactions of endogenous EGFR and HER2 molecules in genome-edited cells using single-molecule live-cell imaging. Furthermore, we show that the interaction with HER2 could allow EGFR to resist endocytosis. Together, this work deepens our understanding of the unique structural properties and dynamics of the EGFR/HER2 complex.
Declining incidence of cerebral palsy in South Korea: Linked analysis of the National Health Insurance database and the health screening data
Authors: Kim Gun-Ha , Lee Gisu , Ha Sungyeon , Cho Geum Joon , Kim Yoon Ha
Published: January 2023

Background
Presuming that the prevalence of cerebral palsy (CP) in Korea is decreasing due to medical advances, we analyzed the trends and risk factors of CP in changing circumstances.
Methods
We identified all women who delivered a singleton between 2007 and 2015 using the Korea National Health Insurance (KNHI). Information on pregnancy and birth was obtained by linking the KNHI claims database and data from the national health-screening program for infants and children.
Results
Over 90% of children with CP were diagnosed within four years of birth. Moreover, the 4-year incidence of CP decreased significantly from 4.77 to 2.52 per 1000 babies during the study period. Multivariate analysis showed that the risk of developing CP was 3.9 times higher in babies with preterm birth, 5.6 times higher in those with birth weight <2500 g, and 4.1 times higher in pregnancies with polyhydramnios. Over time, the number of preterm births and babies with low birth weight decreased, while polyhydramnios became slightly more prevalent.
Conclusion
In Korea, the incidence of CP in singleton decreased from 2007 to 2015. In addition, the number of preterm births and babies with a low birth weight, which are major risk factors for CP, also declined.