bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding the Role of Bispecific Antibodies in the Management of B-Cell Non-Hodgkin Lymphoma: A New Immunotherapy That Is Here to Stay
Authors: Ivanov Stanislav , Muminovic Meri , Sandoval-Sus Jose
Published: October 2023

Non-Hodgkin lymphomas (NHLs) represent a diverse group of hematologic malignancies derived from various cells. B-cell NHLs represent the largest fraction of lymphomas diagnosed and treated in the United States. Standard chemo-immunotherapies with rituximab and multiagent cytotoxic regimens have proven to be effective in the management of these lymphoproliferative neoplasms; nonetheless, a considerable fraction of patients still experience relapse or have treatment-refractory disease. Therapeutic advances using novel immunotherapeutic agents as well as cell-based treatments, such as chimeric antigen receptor (CAR) T-cell therapies, have improved the outcomes of relapsed/refractory (R/R) B-cell NHL. Most of these new treatment strategies are not curative and most patients succumb to R/R disease, leaving this population with an unmet need for effective and well-tolerated therapeutic options. One of these up-and-coming options are bispecific antibodies (BsAb), either as single agent or in combination with other medications. Conclusion: BsAbs offer a novel “off the shelf” chemotherapy-free approach in the management of R/R B-cell NHL. Advancements in antibody construct design along with improved safety profile and clinical effectiveness of the most recent BsAbs suggest that these agents are a promising new option in the management of R/R B-cell NHL.
Analysis of Crack Propagation Behaviors in RPV Dissimilar Metal Welded Joints Affected by Residual Stress
Authors: Zhao Lingyan , Sun Yuchun , Shi Zheren , Yang Bin
Published: October 2023

In severe service environments, the presence of high local residual stress, significant organizational gradient, and nonlinear changes in material properties often leads to stress corrosion cracking (SCC) in dissimilar metal welded (DMW) joints. To accurately predict the crack growth rate, researching the initiation and propagation behavior of SCC cracks in DMW joints under residual stress (RS) is one of the most important methods to ensure the safe operation of nuclear power plants. Using the extended finite element method (XFEM), the crack propagation behaviors in DMW joints under different RS states are predicted and compared. The effects of RS, crack location, and initial crack length on crack propagation behavior are investigated. The crack in a DMW joint without RS deflects to the material of low yield strength. High residual stress urges the crack growing direction to deflect toward the material of high yield strength. Young’s modulus has little impact on the crack deflection paths. The distance between the specimen symmetric line and the boundary line has little effect on the crack initiation and propagation within the RS field. A long initial crack is more likely to initiate and propagate than a short crack. To a long crack and the crack that is far from the interface of two materials, the impact of residual stress on the crack propagation path is significant when it is located in a material with high yield strength, while when the initial crack is located in the material with low yield strength, RS has a great influence on the deflection of a short crack growth direction on the condition that the crack is adjacent to the interface.
Synthesis of Imidazole-Based Deep Eutectic Solvents as Solid Lubricants: Lubricated State Transition
Authors: Zhang Houjie , Chen Youming , Chu Aimin , Hu Hairong , Zhao Yuping
Published: October 2023

The controllable character of the melting point of deep eutectic solvents (DESs) makes it easy to realize lubricated state transitions and produce excellent lubricating properties during friction. In this work, a series of novel imidazole-based DESs were synthesized to present a room-temperature solid state by shifting its eutectic point. Tribological test results show that the wear volume of these DESs decreases as the alkyl chains of the hydrogen bond donors increase. A proper deviation of the eutectic point in DESs produces stable lubricating properties. The present work provides a novel and simple method to prepare solid lubricants and enriches the use of DESs as lubricants. Simultaneously, the method expected to replace the use of conventional cutting fluids.
Construction of Human Periodontal Ligament Constitutive Model Based on Collagen Fiber Content
Authors: Wu Bin , Li Na , Liu Mao , Cheng Ke , Jiang Di , Yi Yang , Ma Songyun , Yan Bin , Lu Yi
Published: October 2023

Periodontal ligament (PDL) is mainly composed of collagen fiber bundles, and the content of collagen fiber is an important factor affecting the mechanical properties of PDL. Based on this, the purpose of this study is to explore the effect of the PDL collagen fiber content on its viscoelastic mechanical behavior. Transverse and longitudinal samples of different regions of PDL were obtained from the human maxilla. The fiber content at different regions of human PDL was quantitatively measured using image processing software, and a new viscoelastic constitutive model was constructed based on the fiber content. The nano-indentation experiment was carried out with a loading rate of 0.5 mN·s−1, a peak load of 3 mN, and a holding time of 200 s, and the model parameters were obtained through the experiment data. The results showed that with the increase of fiber content, the deformation resistance of PDL also increased, and compared with the neck and middle region, the compressive strain in the apical region of PDL was the largest. The range of reduced elastic modulus of human PDL was calculated to be 0.39~5.08 MPa. The results of the experimental data and the viscoelastic constitutive model fit well, indicating that the model can well describe the viscoelastic behavior of human PDL.
Large-Area Mapping of Voids and Dislocations in Basal-Faceted Sapphire Ribbons by Synchrotron Radiation Imaging
Authors: Argunova Tatiana S. , Kohn Victor G. , Lim Jae-Hong , Krymov Vladimir M. , Gutkin Mikhail Yu.
Published: October 2023

The understanding of structural defects in basal-faceted sapphire ribbons was improved through X-ray imaging at a synchrotron source. The combination of phase contrast and X-ray diffraction makes it possible to visualize and characterize both gas voids and dislocations in the bulk of the ribbons grown by the Stepanov–LaBelle technology. Dislocations were directly related to gas voids. X-ray diffraction topography was employed to investigate the distribution, configurations, and character of the dislocations. The formation of voids of irregular shapes was detected by large-area mapping with spatial resolution in the μm range. Computer simulations of the experimental phase contrast images of microvoids were performed. The sizes of the spherical microvoids were determined. The results are discussed with reference to the available data on the emission of dislocations from the voids. The evolution of the shape, size, and arrangement of the voids during growth provides clues on the formation of block structure in basal-faceted sapphire ribbons.
Effect of Melt-Spinning Parameters on the Structure and Properties of Ni55.5Mn18.8Ga24Si1.7 Heusler Alloy Ribbons
Authors: Bhale Pranav , Ari-Gur Pnina , Noebe Ronald D. , Ren Yang , Madiligama Amila , Devaraj Ranjith , Cook Matthew S.
Published: October 2023

Ni–Mn-based Heusler alloys are known to demonstrate magnetic shape memory and giant magnetocaloric effect (MCE). These effects depend on the phases, crystallographic and magnetic phase transitions, and the crystallographic texture characteristics. These structural characteristics, in turn, are a function of the processing parameters. In the current work, Ni55.5Mn18.8Ga24Si1.7 Heusler alloy was processed by melt-spinning under a helium atmosphere. This process results in a fine microstructure. The ribbon that was produced with a narrower nozzle width, faster wheel speed, and higher cast temperature, indicating a faster cooling rate, had double the magnetic entropy change close to room temperature. However, the other ribbon demonstrated a large entropy change over a broader temperature range, extending its usability. The effect of the melt-spinning process parameters on the developing microstructure, crystallographic structure and texture, transformation temperatures, and the magnetic entropy change were studied to explain the difference in magnetocaloric behavior.
Study on the Dynamic Mechanical Properties of Ultrahigh-Performance Concrete under Triaxial Constraints
Authors: Zhang Wei , Mao Jize , Yu Xiao , Zhou Bukui , Wang Limei
Published: October 2023

To confirm the effect of confining pressure on the dynamic mechanical behavior of ultrahigh-performance concrete (UHPC), this study used a true triaxial split Hopkinson pressure bar test system to perform dynamic compression tests on UHPC under triaxial constraints. The confining pressure range considered was 5~10 MPa, the strain rate range was 35~80 s−1, and the steel fiber contents were 0.5%, 1% and 2%. The three-dimensional dynamic engineering stress-strain relationship and equivalent stress-strain relationship of UHPC under different confining pressures and different strain rates were obtained and analyzed in detail. The results show that under the confinement condition, the dynamic peak axial stress–strain and dynamic peak lateral stress–strain of UHPC have strong sensitivity to the strain rate. In addition, the dynamic peak lateral stress–strain is more sensitive to the confining pressure than the dynamic axial stress. An empirical strength enhancement factor (DIFc) that considers the strain rate effect and confining pressure was derived, and the impact of the coupling between the enhancement caused by the confining pressure and the strain rate effect on the dynamic strength of the UHPC under triaxial confinement was discussed. A dynamic strength failure criterion for UHPC under triaxial constraint conditions was established.
Research on the Performance of Superhydrophobic Cement-Based Materials Based on Composite Hydrophobic Agents
Authors: Luo Jie , Xu Yi , Chu Hongqiang , Yang Lu , Song Zijian , Jin Weizhun , Wang Xiaowen , Xue Yuan
Published: October 2023

The utilization of a novel monolithic superhydrophobic cement material effectively prevents water infiltration and enhances the longevity of the material. A method for improving superhydrophobic concrete was investigated with the aim of increasing its strength and reducing its cost by compounding superhydrophobic substances with water repellents. The experimental tests encompassed the assessment of the compressive strength, contact angle, and water absorption of the superhydrophobic cementitious materials. The findings demonstrate that an increase in the dosage of isobutyltriethoxysilane (IBTES) progressively enhances the contact angle of the specimen, but significantly diminishes its compressive strength. The contact angle of SIKS mirrors that of SIS3, with a superior compressive strength that is 68% higher. Moreover, superhydrophobicity directly influences the water absorption of cementitious materials, with a more pronounced superhydrophobic effect leading to a lower water absorption rate. The water absorption of cementitious materials is influenced by the combined effect of porosity and superhydrophobicity. Furthermore, FT−IR tests unveil functional mappings, such as -CH3 which can reduce the surface energy of materials, signifying successful modification with hydrophobic substances.
Effect of the Equal Channel Angular Pressing on the Microstructure and Phase Composition of a 7xxx Series Al-Zn-Mg-Zr Alloy
Authors: Ahmed Anwar Qasim , Olasz Dániel , Bobruk Elena V. , Valiev Ruslan Z. , Chinh Nguyen Q.
Published: October 2023

A supersaturated Al-4.8%Zn-1.2%Mg-0.14%Zr (wt%) alloy was processed by the equal-channel angular pressing (ECAP) technique at room temperature in order to obtain an ultrafine-grained (UFG) microstructure having an average grain size of about 260 nm. The hardness and microstructural characteristics, such as the phase composition and precipitations of this UFG microstructure were studied using depth-sensing indentation (DSI), transmission electron microscopy (TEM), as well as non-isothermal scanning of differential scanning calorimetry (DSC), and compared to the properties of the un-deformed sample. Emphasis was placed on the effect of the UFG microstructure on the subsequent thermal processes in DSC measurements. It has been shown that the ECAP process resulted in not only an ultrafine-grained but also a strongly precipitated microstructure, leading to a hardness (2115 MPa) two and a half times higher than the initial hardness of the freshly quenched sample. Because of the significant changes in microstructure, ECAP has also a strong effect on the dissolution (endothermic) and precipitation (exothermic) processes during DSC measurements, where the dissolution and precipitation processes were quantitatively characterized by using experimentally determined specific enthalpies, ΔH and activation energies, Q.
Numerical Analysis of the Freezing Behavior of Saturated Cementitious Materials with Different Amounts of Chloride
Authors: Zadran Sekandar , Ožbolt Joško , Gambarelli Serena
Published: October 2023

The freezing behavior of cement paste saturated with different chloride concentrations is investigated numerically with a coupled 3D hygro-thermo-mechanical FE analysis. The mathematical formulation of the freezing processes in the context of poromechanics takes into account the water (hydraulic) and ice pore pressures, as well as the distribution of heat (temperature) and strains. These quantities are calculated numerically based on three coupled differential equations, namely the static equilibrium equation and the equations for the transport of water and heat. The coupling between the mechanical (loading) and the non-mechanical processes (freezing) is performed using a staggered solution scheme. The proposed numerical approach is first validated using numerical and experimental studies from the literature dealing with two different cement pastes saturated with different amounts of chloride. The validated model is then used to investigate the effects of liquid water permeability, total porosity and pore size distribution on the freezing behavior of hardened cement paste. The results show that liquid water permeability has a strong effect on the pore pressure and deformation of the hardened cement paste. It is also shown that by decreasing the total porosity, the material becomes denser and contracts more as the temperature decreases, leading to a decrease in freezing strain. The results of this paper will provide important findings for the development of a simplified engineering model to investigate the mechanism that leads to freeze–thaw salt-induced damage to concrete structures in the framework of the DFG-funded research project.
Delamination Behavior of CFRP Laminated Plates under the Combination of Tensile Preloading and Impact Loading
Authors: Lan Kaiwei , Wang Haodong , Wang Cunxian
Published: October 2023

When subjected to impact loading, aircraft composite structures are usually in a specific preloading condition (such as tension and compression). In this study, ballistic tests were conducted using a high-speed gas gun system to investigate the effect of biaxial in-plane tensile preload on the delamination of CFRP laminates during high-speed impact. These tests covered central and near-edge locations for both unloaded and preloaded targets, with the test speeds including 50 m/s, 70 m/s, and 90 m/s. The delamination areas, when impacting the center location under 1000 με, show a 14.2~36.7% decrease. However, the cases when impacting the near-edge location show no more than a 19.3% decrease, and even more delamination areas were observed. In addition, in order to enhance the understanding of experimental phenomena, numerical simulations were conducted using the ABAQUS/Explicit solver, combined with the user subroutine VUMAT with modified Hou criteria. The experimental and simulation results were in good agreement, and the maximum error was approximately 12.9%. The results showed that not only the preloading value but also the impact velocity have significant influences on the delamination behavior of preloaded CFRP laminated plates. Combining detailed discussions, the biaxial tensile preload enhanced the resistance to out-of-plane displacement and caused laminate interface stiffness degradation. By analyzing the influence of the preloading value and impact velocity on competing mechanisms between the stress-stiffening effect and interface stiffness degradation effect, the complex delamination behaviors of laminates under various preloading degrees and impact velocities at different impact locations were reasonably explained.
Review of the Influence of Acrylate Lotion on the Properties of Cement-Based Materials
Authors: Su Fuyun , Wang Haiyan , Ma Xiaodong , He Tingshu , Lin Yike
Published: October 2023

Polymer-modified cement-based materials have been widely used in the construction field. Acrylate lotion significantly improves durability, toughness, and bending resistance, especially durability, because the porosity of cement-based materials is reduced, preventing the entry of harmful ions and water. When acrylate lotion was at 20%, the resistance of cement-based materials to chloride ion penetration increased by 40%. At the same time, the fracture toughness of cement-based materials modified with acrylate lotion and carbon nanotubes increased by 10–15%. The flexural strength of cement-based materials modified by acrylate lotion and fiber increased by 29%. Additives such as TiO2 have a unique impact on the modification of cement-based materials, which has attracted the interest of researchers. This paper reviewed the performance of acrylate lotion-modified cement-based materials and the application of acrylate lotion in the field, which systematically increased the durability, mechanical properties, and waterproof properties of cement-based materials when acrylate lotion was modified, acrylate lotion was modified with nanomaterials, acrylate lotion was modified with other polymers, acrylate lotion was modified with fiber, and when acrylate lotion was modified with other additives. The shortcomings of acrylate lotion modification with different materials were reviewed and evaluated, and the comprehensive performance of cement-based materials modified by acrylate lotion was expected to achieve maximum strength improvement under the synergistic effect of various modifications.
An Orthogonal Test Study on the Preparation of Self-Compacting Underwater Non-Dispersible Concrete
Authors: Geng Haibin , Wang Huijuan , Li Xiaoke , Wang Lin , Zhong Hao , Li Changyong
Published: October 2023

To ensure a limited washout loss rate and the self-compaction of underwater concrete, the mix proportion design of underwater non-dispersible concrete is a key technology that has not been completely mastered. In view of this aspect, an orthogonal test study was carried out in this paper on the workability, washout resistance, and compressive strength of underwater non-dispersible concrete. Six factors with five levels were considered, which included the water/binder ratio, the sand ratio, the maximum particle size of the coarse aggregate, the content of the dispersion resistance agent, the content of superplasticizer, and the dosage of fly ash. Using a range and variance analysis, the sensitivity and significance of these factors were analyzed on the slump and slump-flow, the flow time, the washout loss rate, the pH value, and the compressive strength at the curing ages of 7 days and 28 days. The results indicated that the water/binder ratio and the content of the dispersion resistance agent were strong in terms of their sensitivity and significance on the workability and washout resistance, and the water/binder ratio and the dosage of fly ash were strong in terms of their sensitivity and significance on the compressive strength. With the joint fitness of the test results, formulas for predicting the slump-flow, washout loss rate, and compressive strength of underwater non-dispersible concrete were proposed considering the main impact factors.
Lone-Pair-Enabled Polymorphism and Photostructural Changes in Chalcogenide Glasses
Authors: Kolobov Alexander V. , Kuznetsov Vladimir G. , Krbal Milos , Zabotnov Stanislav V.
Published: October 2023

S- and Se-based chalcogenide glasses are intrinsically metastable and exhibit a number of photo-induced effects unique to this class of materials, reversible photostructural changes and photo-induced anisotropy being major examples. These effects are usually interpreted in terms of the formation of valence alternation pairs and ‘wrong’ bonds. In this work, using density functional theory simulations, we demonstrate for the case example of As2S3 that a strong decrease in the optical band gap can be achieved if a polymorphic transformation of the local structure from orpiment to that of tetradymite takes place. For the formation of the latter, the presence of lone-pair electrons in near-linear atomic configurations is crucial. Our results represent a novel approach to understanding the photo-induced structural changes in chalcogenide glasses as being due to the presence of polymorphism, and will lead to their wider use in various photonic devices.
A Numerical and Experimental Analysis of the Mechanical Behavior of the Aluminum Beverage Can with Internal Varnish Layers during Axial Load Force Testing
Authors: Wędrychowicz Przemysław , Kustra Piotr , Milenin Andrij
Published: October 2023

This article presents a numerical and experimental investigation into the impact of can wall thickness and the internal varnish layer thickness on the results of an axial load force test. This study also shows the levels of thermal stresses that emerge after the drying of varnish coating, and how they affect the results of the axial load force test. This research involves the development of suitable numerical models and the experimental acquisition of stress–deformation relationships for the both can material, aluminum, and the varnish. The numerical simulation of the axial load force test has been verified through experimental tests, with a resulting difference of 8.9% between the two sets of results. The findings highlight that changes in the can wall thickness have a more pronounced effect on test outcomes compared to variations in the varnish thickness. Specifically, an increase in the can wall thickness from 90 µm to 100 µm results in a substantial 116 N increase in the force required for a can to collapse. Nevertheless, the presence of a 5 µm varnish layer also contributes measurably, increasing the can’s collapse force by 21 N. These results offer valuable practical insights for manufacturers, enabling them to effectively optimize can strength characteristics.
Crashworthiness of Foam-Filled Cylindrical Sandwich Shells with Corrugated Cores
Authors: Su Pengbo , Han Bin , Wang Yiming , Wang Hui , Gao Bo , Lu Tian Jian
Published: October 2023

Inspired by material hybrid design, novel hybrid sandwich shells were developed by filling a corrugated cylindrical structure with aluminum foam to achieve higher energy absorption performance. The crushing behavior of the foam-filled corrugated sandwich cylindrical shells (FFCSCSs) was investigated using theoretical and numerical methods. Numerical results revealed a significant enhancement in the energy absorption of FFCSCSs under axial compression, showcasing a maximum specific energy absorption of 60 kJ/kg. The coupling strengthening effect is highly pronounced, with a maximum value of F¯c/F¯ reaching up to 40%. The mechanism underlying this phenomenon can be approached from two perspectives. Firstly, the intrusion of folds into the foam insertions allows for more effective foam compression, maximizing its energy absorption capacity. Secondly, foam causes the folds to bend upwards, intensifying the mutual compression between the folds. This coupling mechanism was further investigated with a focus on analyzing the influence of parameters such as the relative density of the foam, the wall thickness of the sandwich shell, and the material properties. Moreover, a theoretical model was developed to accurately predict the mean crushing force of the FFCSCSs. Based on this model, the influence of various variables on the crushing behavior of the structure was thoroughly investigated through parametric studies.
Fabrication and Characterization of a Multifunctional Coating to Promote the Osteogenic Properties of Orthopedic Implants
Authors: Koc Serap (Gungor) , Baygar Tuba , Özarslan Selma , Sarac Nurdan , Ugur Aysel
Published: October 2023

Titanium-based alloys are used in orthopedic applications as fixation elements, hard tissue replacements in artificial bones, and dental implants. Despite their wide range of applications, metallic implant defects and failures arise due to inadequate mechanical bonding, postoperative clotting problems, aseptic loosening, and infections. To improve the surface bioactivity and reduce the corrosion rate of the Ti6Al4V alloy, multi-layered coatings (HAp, BG, Cs, and Hep) were applied via electrophoretic deposition (EPD). XRD images showed the presence of HAp within the coating. In vitro investigation: cell line NIH-3T3 fibroblasts were seeded on the non-coated and coated Ti6Al4V substrates, and their cellular behavior was evaluated. The results indicated that the HApBGCsHep coating could enhance the adhesion and proliferation of NIH 3T3 cells. In addition, the potentiodynamic polarization results are compatible with the in vitro outcome.
Residual Stress Control Using Process Optimization in Directed Energy Deposition
Authors: Cheng Manping , Zou Xi , Pan Yang , Zhou Yan , Liu Wenyang , Song Lijun
Published: October 2023

This paper mainly analyzes the typical thermodynamic response (thermal history, thermal strain and residual stress) in a conventional continuous-wave (CW) laser during Directed Energy Deposition (DED). The influence of process parameters (laser power and scanning speed) on the temperature gradient in the heat-affected zone, thermal strain and residual stress are studied, and the corresponding relationship are established. The results show that a reduction in residual stress can be obtained by decreasing the temperature gradient. However, the method of reducing the temperature gradient by changing process parameters leads to low forming quality and low density. A pulse-wave laser (PW) is proposed to actively control the residual stress of the deposited sample. This laser mode can reduce not only the temperature gradient in the process of DED but also the in situ release of thermal stress, correspondingly greatly reducing the residual stress.
Improved Interlaminar Properties of Glass Fiber/Epoxy Laminates by the Synergic Modification of Soft and Rigid Particles
Authors: Liu Jingwei , Tian Shenghui , Ren Jiaqi , Huang Jin , Luo Lin , Du Bing , Zhang Tianyong
Published: October 2023

Poor interlaminar fracture toughness has been a major issue in glass fiber-reinforced epoxy resin (GF/EP) laminate composites. In this paper, soft carboxy-terminated nitrile (CTBN) rubber particles and rigid nano-SiO2 are used to toughen the epoxy resin (EP) matrix to improve the interlayer properties of GF/EP laminate composites. The effects of adding two toughening agents on the mechanical and interlayer properties of GF/EP laminates were studied. The results showed that adding the two kinds of particles improved the mechanical properties of the epoxy matrix. When the additional amount of flexible CTBN rubber particles was 8 wt%, and the rigid nano-SiO2 was 0.5 wt%, the fracture toughness of the matrix resin was increased by 215.8%, and the tensile strength was only decreased by 2.3% compared with the pure epoxy resin. On this basis, the effects of two kinds of particles on the interlayer properties of GF/EP composites were studied. Compared with the unmodified GF/EP laminates, the interlayer shear strength and mode I interlayer fracture toughness is significantly improved by a toughening agent, and the energy release rate GIC of interlayer shear strength and interlayer fracture toughness is increased by 109.2%, and 86.8%, respectively. The flexible CTBN rubber particles and rigid nano-SiO2 improve the interfacial adhesion between GF and EP. The cavitation of the two particles and the plastic deformation of the matrix is the toughening mechanism of the interlayer properties of the composite. Such excellent interlaminar mechanical properties make it possible for GF/EP laminates to be widely used as engineering materials in various industries (e.g., aerospace, hydrogen energy, marine).
Development of a Novel High-Temperature Microemulsion for Enhanced Oil Recovery in Tight Oil Reservoirs
Authors: Xiao Lixiao , Hou Jirui , Wang Weiju , Raj Infant
Published: October 2023

This work focuses on the development of a novel high-temperature microemulsion for enhanced oil recovery in tight oil reservoirs. Microemulsions are a type of mixture that has properties of both liquids and solids; they have shown significant potential for improving oil recovery through spontaneous imbibition. Herein, a high-temperature-tolerant lower-phase microemulsion using a microemulsion dilution method was developed. The properties and morphological characteristics of the microemulsion were evaluated and proposed a mechanism for enhanced spontaneous imbibition oil recovery using imbibition tests and CT scanning technology. The results of the study showed that the optimum concentration of the microemulsion was 0.2 wt% and that it had good thermal stability, small droplet size, lower interfacial tension, good wettability alteration ability, and minimum adsorption loss. The imbibition and CT experiments demonstrated that the reduction in oil/solid adhesion was due to the synergistic effect of IFT reduction and wettability alteration and the ability to increase the imbibition distance through a larger self-driving force. The study concludes that the solubilization coefficient and self-driving force were defined and calculated to quantitatively analyze the imbibition mechanisms and the results showed that the reduction in oil/solid adhesion was due to the synergistic effect of IFT reduction and wettability alteration and the ability to increase the imbibition distance through a larger self-driving force.
Composite Resins Impregnated by Phosphorus Organic Extractants for Separation of Rare Earth Elements from Nitrate-Based Leachate of Permanent Magnets
Authors: Kovalenko Olga V. , Baulin Vladimir E. , Shulga Yuri M. , Baulin Dmitriy V. , Gutsev Gennady L. , Tsivadze Aslan Yu.
Published: October 2023

Composite resins impregnated by different organophosphorus extractants were developed and used for the extraction chromatography recovery of rare earth elements from nitrate-based leachate of NdFeB permanent magnets. The influence of different factors on recovery of Nd(III) and Fe(III), as the most difficult to separate elements, by developed resins was studied. The influence of extractant structure, the composition of feed solutions, and concentrations of HNO3 and NH4NO3 on the recovery of Fe(III) and Nd(III) by prepared resins were considered. The best recovery of Nd(III) was shown by resin impregnated with N,N-dioctyl (diphenylphosphoryl) acetamide. For this material, sorption characteristics (values of the distribution coefficient, capacity, and the Nd(III)/Fe(III) separation factor) were obtained, and the reproducibility of the loading–stripping process was evaluated. This resin and its precursors were characterized by IR spectroscopy. It was found that the developed resin is more efficient for Nd(III) recovery than resin impregnated with TODGA. An effective approach to the Nd(III)/Fe(III) separation with developed resin in nitrate solution was proposed. This approach was used for recovery of Pr(III), Nd(III), and Dy(III) from the nitrate-based leachate of NdFeB magnets by the developed resin. The final product contained 99.6% of rare earths.
Data-Driven Active Learning Control for Bridge Cranes
Authors: Lin Haojie , Lou Xuyang
Published: October 2023

For positioning and anti-swing control of bridge cranes, the active learning control method can reduce the dependence of controller design on the model and the influence of unmodeled dynamics on the controller’s performance. By only using the real-time online input and output data of the bridge crane system, the active learning control method consists of the finite-dimensional approximation of the Koopman operator and the design of an active learning controller based on the linear quadratic optimal tracking control. The effectiveness of the control strategy for positioning and anti-swing of bridge cranes is verified through numerical simulations.
Influence of the Fiber Post Length on the Fracture Strength of Endodontically Treated Teeth
Authors: Marinescu Adrian-George , Abuabboud Osama , Zimbru Ștefana-Denisa , Cîrligeriu Laura-Elena , Piț Bianca-Adina , Borcean Ioana-Amalia , Paven Mihai , Nica Luminița-Maria , Stoia Dan Ioan
Published: October 2023

Background and Objectives: Although fiber posts are widely used in the restoration of endodontically treated teeth (ETT), their ideal cementation depth into the root canal is still debated in literature. The aim of the present study was to evaluate whether the different intra-radicular insertion lengths of the fiber posts influence the fracture strength of ETT. Materials and Methods: A total of 10 permanent human lower incisors with straight roots of similar length and volume extracted for periodontal reason were sectioned 2 mm above the cement–enamel junction (CEJ) to a total length of 18 mm and endodontically treated in the same manner, then randomly divided into two groups of five each (Groups 1 and 2, n = 5). Two sound incisors, with no endodontic treatment, were used as the control group (Group 3, n = 2). After one week of storage in a humid environment, spaces for fiber post no. 1 (Reforpost, Angelus, Londrina, PR, Brazil) were prepared in the first two groups at a depth of 5 mm (Group 1) and 7 mm (Group 2), and the fiber posts were adhesively cemented using self-adhesive resin cement (Maxcem Elite, Kerr GmbH, Herzogenrath, Germany). After 7 days, the samples were vertically positioned and fixed in a self-curing transparent acrylic resin, up to 2 mm below the CEJ level, and mechanically tested in compression after another week of storage using a displacement-controlled testing machine up to each sample’s fracture. The force–displacement curves were recorded for each sample, the means were calculated for each group and a statistical comparative analysis between groups was conducted. Results: Although no statistically significant differences between groups were observed, the highest mean fracture force (N) was recorded in Group 2 (1099.41 ± 481.89) in comparison to Group 1 (985.09 ± 330.28), even when compared to the sound, non-treated teeth (1045.69 ± 146.19). Conclusions: Within the limitations of this in vitro study, teeth where fiber posts were placed deeper into the root canal (7 mm) recorded slightly higher fracture forces in comparison with shorter lengths (5 mm). However, similar biomechanical performances obtained in the mechanical tests showed no statistical differences between the 7 mm and the 5 mm inserted posts.
Association of Maternal Risk Factors with the Prevalence of Caesarean Section Deliveries: A Cross-Sectional Study
Authors: Pavlidou Eleni , Antasouras Georgios , Papadopoulou Sousana K. , Alexatou Olga , Papandreou Dimitrios , Mentzelou Maria , Tsourouflis Gerasimos , Louka Aikaterini , Rodopaios Nikolaos E. , Chrysafi Maria , Sampani Anastasia , Giaginis Constantinos
Published: October 2023

In the last few years, there has been a gradually increasing rate of caesarean section deliveries worldwide that negatively affects both mothers’ and children’s health. The present survey intended to explore the relations of common maternal risk factors with the prevalence of caesarean sections. This is a cross-sectional study including 5182 healthy mothers from geographically diverse regions of Greece, which has applied relevant inclusion and exclusion criteria. An elevated 56.4% incidence of caesarean sections was noted. The prevalence of caesarean section deliveries was estimated to be 51.5% in private hospitals and 48.5% in public hospitals. Maternal age, pre-pregnancy overweight/obesity, excess gestational weight gain, preterm birth, financial status, smoking habits, and private type of birth hospital were considerably associated with a high probability of caesarean section, regardless of several confounders. In conclusion, caesarean section rates are constantly increasing, and various maternal risk factors additively elevate its incidence, which additionally enhances the likelihood of postpartum complications for both the mothers and their infants. Public health procedures and approaches are strongly recommended to notify future mothers of the potential risk factors that may result in adverse pregnancy outcomes of caesarean section delivery, highlighting its use only for emergency medical reasons and also promoting healthier nutritional and lifestyle habits that may reduce the increasing prevalence of caesarean section deliveries.
CFD-Assisted Process Optimization of an Integrated Photocatalytic Membrane System for Water Treatment
Authors: Chakachaka Vimbainashe Mercy , Tshangana Charmaine Sesethu , Mamba Bhekie Brilliance , Muleja Adolph Anga
Published: October 2023

An integrated photocatalytic membrane system (IPMS) was developed for potential use in the remediation of naproxen using real water samples from a drinking water treatment plant. Key parameters such as time, pH, water matrix, mixing speeds, flow rate, and light intensity undeniably affected photocatalytic and membrane separation processes. The system optimization was based on improving irradiation to generate a more reactive species and mass transfer to increase the reaction rate. Upon optimization, IPMS achieved 99% naproxen removal efficiency. Computational fluid dynamics (CFD) simulated the flow patterns and radiation distribution inside the photocatalytic membrane reactor to improve irradiation and mass transfer during operation. The simulated flow field revealed the presence of dead zones with different velocities in the photocatalytic membrane reactor; this limited the mass transfer of reactive species in the reactor, resulting in uneven distribution of reactive radicals. The dead zones were mitigated by increasing the mixing speed, and as a result, convective mass flow improved process performance. The governing parameters (flow patterns and radiation distribution) of the simulated and experimental data were in agreement. The absorption of irradiation by the active site of the membranes improved with light intensity; at higher light intensities, the light irradiated deeper into the membrane. As such, the CoFe2O4 nanoparticles incorporated inside the membrane pores became highly activated, thus enhancing degradation. The obtained space–time yield (STY) (1.23 × 1011 mol/cm2.s) and photocatalytic space–time yield (PSTY) (4.39 × 1011 mol/W.s) showed that the developed IPMS was efficient regarding energy intensiveness and throughput for treatment of pollutants in water.
Materialization of the Heat-Affected Zone with Laser Tailor-Welded HPF 22MnB5 Steel Using FLD and the Fracture Displacement Method in FE Simulation
Authors: Jeon Hyeon Jong , Jin Chul Kyu , Lee Min Sik , Lim Ok Dong , Kang Nam Su
Published: October 2023

Using a tailor-welded blank (TWB) and hot-press forming (HPF), a 22MnB5 blank was surface-treated under four conditions. The penetration rates of the FexAly compounds under the four surface-treatment conditions were investigated, and the hardness values were measured. A finite element (FE) simulation was performed for the characteristics of the heat-affected zone (HAZ), using the hardness value and results of previous researchers. In particular, the mechanical property settings of the mesh were designed to realize the conditions for the FexAly compounds in the HAZ. Fine meshing was performed by partitioning the HAZ sections. For the mechanical properties of the HAZ with the FexAly compounds, the strength was predicted from the hardness value, and the elongation values investigated by other researchers were used. The forming limit diagram, which was proportional to the elongation, was predicted. Specific elements were defined as the areas with FexAly compounds, which played the same role as impurities. Tensile TWB–HPF specimens with different HAZ characteristics under four surface-treatment conditions were fabricated. Experiments and FE simulations were performed and compared. Details are as follows: For loads, a minimum error rate of 3% and a maximum error rate of 6% were obtained. For displacement, a minimum error rate of 9% and a maximum error of 25% were obtained. The feasibility of the simulation was verified by comparing the simulation and experimental results. A match of more than 75% was obtained.
Effect of Repeated Processing Passes during Ultrasonic Rolling on Fatigue Performance and Corrosion Resistance of Ti6Al4V Alloy
Authors: Wang Shuaixing , Yu Tianjian , Pang Zhiwei , Yin Xiaole , Liu Xiaohui
Published: October 2023

Ultrasonic surface rolling processing (USRP) is a new method to improve the fatigue performance of titanium alloy, and repeated processing pass is an important factor that affects its strengthening effect. The effect of USRP passes on the surface microstructure, residual stress, fatigue performance and corrosion resistance of titanium alloy is researched via SEM, X-ray diffractometer, rotating–bending fatigue test and electrochemical impedance spectroscopy. The results show that Ti6Al4V alloy undergoes cumulative plastic deformation during USRP process, the surface grains are refined and a residual compressive stress field with a thickness of 500 μm is introduced, which together improve the fatigue performance of the Ti6Al4V alloy. Increasing the repeated processing passes will deepen the grain refinement layer and increase the surface hardening effect, but the fatigue life of the Ti6Al4V alloy does not increase with an increase in processing passes. A five-passes processing under a static force of 550 N can result in a greater gain for the fatigue resistance of the Ti6Al4V alloy; the fatigue life of a five-passes-processed sample under 600 MPa is 8 times higher than that of an untreated sample, and its fatigue crack source initiates at the subsurface away from the surface of 180 μm. Furthermore, Ti6Al4V alloys treated by USRP show a better corrosion resistance in both neutral and acidic solutions, especially for the five-passes-processed sample.
Advancements in Wearable and Implantable Intraocular Pressure Biosensors for Ophthalmology: A Comprehensive Review
Authors: Wu Kevin Y. , Mina Mina , Carbonneau Marjorie , Marchand Michael , Tran Simon D.
Published: October 2023

Glaucoma, marked by its intricate association with intraocular pressure (IOP), stands as a predominant cause of non-reversible vision loss. In this review, the physiological relevance of IOP is detailed, alongside its potential pathological consequences. The review further delves into innovative engineering solutions for IOP monitoring, highlighting the latest advancements in wearable and implantable sensors and their potential in enhancing glaucoma management. These technological innovations are interwoven with clinical practice, underscoring their real-world applications, patient-centered strategies, and the prospects for future development in IOP control. By synthesizing theoretical concepts, technological innovations, and practical clinical insights, this review contributes a cohesive and comprehensive perspective on the IOP biosensor’s role in glaucoma, serving as a reference for ophthalmological researchers, clinicians, and professionals.
Rapid Detection of Malaria Based on Hairpin-Mediated Amplification and Lateral Flow Detection
Authors: Zhang Yang , Ke Lihui , Sun Tao , Liu Yang , Wei Bo , Du Minghua
Published: October 2023

Malaria is listed as one of the three most hazardous infectious diseases worldwide. Travelers and migrants passing through exit and entry ports are important sources of malaria pandemics globally. Developing accurate and rapid detection technology for malaria is important. Here, a novel hairpin-mediated amplification (HMA) technique was proposed for the detection of four Plasmodium species, including P. falciparum, P. vivax, P. malariae, and P. ovale. Based on the conserved nucleotide sequence of Plasmodium, specific primers and probes were designed for the HMA process, and the amplicon can be detected using lateral flow detection (LFD); the results can be read visually without specialized equipment. The specificity of HMA-LFD was evaluated using nucleic acids extracted from four different Plasmodium species and two virus species. The sensitivity of HMA-LFD was valued using 10× serial dilutions of plasmid containing the template sequence. Moreover, 78 blood samples were collected to compare HMA-LFD and qPCR. The HMA-LFD results were all positive for four different Plasmodium species and negative for the other two virus species. The sensitivity of HMA-LFD was tested to be near five copies/μL. The analysis of clinical samples indicated that the consistency of HMA-LFD and qPCR was approximately 96.15%. Based on these results, the HMA-LFD assay was demonstrated to be a rapid, sensitive, and specific technique for the detection of Plasmodium and has great advantages for on-site detection in low-resource areas and exit and entry ports.
Prediction of Au-Polymetallic Deposits Based on Spatial Multi-Layer Information Fusion by Random Forest Model in the Central Kunlun Area of Xinjiang, China
Authors: Zhang Yuepeng , Ye Xiaofeng , Xie Shuyun , Dong Jianbiao , Yaisamut Oraphan , Zhou Xuwei , Zhou Xiaoying
Published: October 2023

In recent years, there has been a growing emphasis on combining intelligent prospecting algorithms, such as random forest, with extensive geological and mineral data for the purpose of quantitatively predicting exploration geochemistry. This approach holds significant importance for enhancing the accuracy of target delineation. The central Kunlun area in Xinjiang possesses highly favorable ore-forming geological conditions, offering excellent prospects for mineral exploration. However, the depletion of shallow deposits coupled with a decade-long gap in geological exploration have presented increasing challenges in the quest to discover substantial metal resources. Consequently, there is now a severe shortage of reserve assets in the region, prompting an urgent need for the implementation of new theories, methods, and technologies in mineral resource investigation and evaluation efforts. The researchers used geological and regional geochemical data to construct a random forest metallogenic discriminant model for predicting the mineralization of gold polymetallic minerals in the central Kunlun area of Xinjiang and delineating the metallogenic target area. Two different sampling methods were compared to quantitatively predict gold polymetallic mineral resources. The results indicate that the selected training samples offer higher prediction accuracy and reliability by fully capturing the complex information of the original data. The random forest model using select training samples has valuable applications in metallogenic prospect prediction and potential division due to its ability to consider the actual exploration cost and identify small areas with high potential and a high proportion of ore. This study significantly improves prediction accuracy, reduces exploration risk, and expands the use of machine learning algorithms in mathematical geology in the central Kunlun area of Xinjiang.