bluuebunny/crossref_metadata_2025 huggingface dataset:
The Health Education Demonstration Methods to Increase the Knowledge Level of Prevention of the Corpus Alienum of Eye toward Welding Workers
Authors: Siswoyo Siswoyo , Kushariyadi Kushariyadi , Winingsih Nur
Published: December 2018

Corpus alienum is any object or substance found in an organ or tissue in which it does not belong under normal circumstances. Corpus alienum of eye can be experienced by welder that do not use eye protective equipment. Health education with demonstration methods is one of the learning methods to improve the knowledge. The purpose of this research is to know the influence of health education by demonstration method toward the knowledge level of the corpus alienum eye’s prevention in welder. This research used pre-experimental with one group pretest-posttest design. The sampling technique was non-probability samplig used total sampling involving 16 respondents. The data were statistically analyzed using wilcoxon test. The result of data analyze showed a significant value (p value = 0.005). Health education with demonstration methods can improve the knowledge of welder so can be minimized the risk of corpus alienum of eye. There were correlation between health education of demonstration methods and the knowledge level of prevention of the corpus alienum of eye to welder in Putra Jaya Sumbersari the districts of Jember. It is expected that nurses can do health education demonstration methods to prevent corpus alienum of eye in welder to be minimized the risk of corpus alienum of eye.
Validity and Reliability of Critical Care Family Needs Inventory (CCFNI) in Indonesian Version
Authors: Wantiyah Wantiyah , A'la Muhamad Zulfatul , Setioputro Baskoro , Siswoyo Siswoyo
Published: December 2018

Family-centered care (FCC) in intensive care as a family-based care approach has been developed for a long time, but this development in Indonesia is still not optimally created. The FCC needs basic data about the needs of the family who are caring for it, so the need for the family can be identified therefore nursing intervention can be done optimally. One measure that has been developed to assess family needs is Critical Care Family Needs Inventory (CCFNI). The purpose of this study was to analyze the CCFNI questionnaire in Indonesian version. This study tried to test the questionnaire through several steps translation into Indonesian, validity testing in the form of validity content documents (CVI) and construct validity and reliability testing. The results of the CVI test on 45 Indonesian language CCFNI questionnaire statements found that the CVI value was in the range 0.6-0.9 obtained 36 valid statement items, while the results of the construct validity test were found to be valid. Reliability test results obtained an alpha value of 0.97 which means it is very reliable. The conclusion is that the Indonesian version of the CCFNI questionnaire which is translated into Kebutuhan Keluarga Pasien di Ruang Perawatan Intensif (K3PI) is valid and reliable.
Integration of UAV, Sentinel-1 and Sentinel-2 Data for Mangrove Plantations Aboveground Biomass Monitoring in Senegal
Authors: Navarro José Antonio , Algeet Nur , Fernández-Landa Alfredo , Esteban Jéssica , Rodríguez-Noriega Pablo , Guillén-Climent María Luz
Published: December 2018

Due to the increasing importance of mangroves in climate change mitigation projects, more accurate and cost-effective aboveground biomass (AGB) monitoring methods are required. However, field measurement of AGB may be a challenge because of its remote location and the difficulty to walk in these areas. This study is based on the Livelihoods Fund’ Oceanium project of 10,000 hectare mangrove plantations monitoring. In a first step, the possibility of replacing traditional field measurements of sample plots in a young mangrove plantation by a semiautomatic processing of UAV-based photogrammetric point clouds was assessed. In a second step, Sentinel-1 radar and Sentinel-2 optical imagery were used as auxiliary information to estimate AGB and its variance for the entire study area under a model-assisted framework. AGB was measured using UAV imagery in a total of 95 sample plots. UAV plot data was used in combination with non-parametric Support Vector Regression (SVR) models for the estimation of the study area AGB using model-assisted estimators. Purely UAV-based AGB estimates and their associated standard error (SE) were compared with model-assisted estimates using (1) Sentinel-1, (2) Sentinel-2 and (3) a combination of Sentinel-1 and Sentinel-2 data as auxiliary information. The validation of the UAV-based individual tree height and crown diameter measurements showed a root mean square error (RMSE) of 0.21 m and 0.32 m respectively. Relative efficiency of the three model-assisted scenarios ranged between 1.61 and 2.15. Although all SVR models improved the efficiency of the monitoring over UAV-based estimates, the best results were achieved when a combination of Sentinel-1 and Sentinel-2 data was used. Results indicated that the methodology used in this research can provide accurate and cost-effective estimates of AGB in mangrove young plantations.
Modified Deep Neural Networks for Dog Breeds Identification
Authors: Ayanzadeh Aydin , Vahidnia Sahand
Published: December 2018

In this paper, we leverage state of the art models on Imagenet data-sets. We use the pre-trained model and learned weighs to extract the feature from the Dog breeds identification data-set. Afterwards, we applied fine-tuning and dataaugmentation to increase the performance of our test accuracy in classification of dog breeds datasets. The performance of the proposed approaches are compared with the state of the art models of Image-Net datasets such as ResNet-50, DenseNet-121, DenseNet-169 and GoogleNet. we achieved 89.66% , 85.37% 84.01% and 82.08% test accuracy respectively which shows thesuperior performance of proposed method to the previous works on Stanford dog breeds datasets.
Recovery of Differential Equations from Impulse Response Time Series Data for Model Identification and Feature Extraction
Authors: Stender Merten , Oberst Sebastian , Hoffmann Norbert
Published: December 2018

Time recordings of impulse-type oscillation responses are short and highly transient. These characteristics may complicate the usage of classical spectral signal processing techniques for a) describing the dynamics and b) deriving discriminative features from the data. However, common model identification and validation techniques mostly rely on steady-state recordings, characteristic spectral properties and non-transient behavior. In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation. With special focus on short and strongly damped oscillations, an optimization procedure is proposed that fine-tunes the reconstructed dynamical models with respect to model simplicity and error reduction. This framework is analyzed with particular focus on the amount of information available to the reconstruction, noise contamination and non-linearities contained in the time series input. Using the example of a mechanical oscillator, we illustrate how the optimized reconstruction method can be used to identify a suitable model and to extract features from uni-variate and multivariate time series recordings in an engineering-compliant environment. Moreover, the determined minimal models allow for identifying the qualitative nature of the underlying dynamical systems as well as testing for the degree and strength of non-linearity. The reconstructed differential equations would then be potentially available for classical numerical studies, such as bifurcation analysis. These results represent a physically interpretable enhancement of data-driven modeling approaches in structural dynamics.
Cell Sheets: From Delivery Tool to a Model of Guided Regeneration
Authors: Nimiritsky Peter , Eremichev Roman , Alexandrushkina Natalia , Efimenko Anastasia , Tkachuk Vsevolod , Makarevich Pavel
Published: December 2018

Regeneration is a fundamental perpetual tissue process much attributed to functions of adult stem cell. In last decades delivery of adult stem cells to restore tissue structure is widely adopted in regenerative medicine. However, delivery of stem cells can not complete the task of human body regeneration effectively as far as cells need a basis to form a tissue. Certain improvement can be achieved when cells are organized to cells sheets (CS) – primitive tissue-engineered structures comprising of viable cells and ECM proteins. This led us to an assumption that after damage an intermediate feeder is structure formed as a ground for future tissue resulting in gradients of stimuli required to attract other cells (vascular, neural, epithelial, parenchyma etc.) in an organized manner. This feeder acquires increasing heterogeneity and becomes a guiding feeder that provides basic level of organization to increase complexity of structure up to normal tissue. We also highlight potential role of adult mesenchymal stromal cells (MSC) as the main source of guiding feeder and support it by our recent knowledge of their biological function. Finally, we assume that CS known to be a feasible delivery tool in therapeutics resemble guiding feeder and show our own data indicating properties of MSC-based CS. Furthermore, this concept shifts our understanding of therapeutic mechanism underlying a widely known delivery method for regenerative medicine.
Determination of Au(III) and Ag(I) in Carbonaceous Shales and Pyrites by Stripping Voltammetry
Authors: Kolpakova Nina A. , Sabitova Zhamilya K. , Sachkov Victor I. , Medvedev Rodion O. , Nefedov Roman A. , Orlov Vladislav V.
Published: December 2018

Techniques of stripping voltammetry (SV) determination of silver and gold in pyrites and carbonaceous matter were developed. The problem of quantitative transfer of the sample into the solution was solved. For this purpose, the ore matrix of carbonaceous shales was decomposed by mineral acids in autoclaves at high pressures. The element to be determined from the sample matrix was separated by extraction. Ag(I) ions from the solutions were extracted in the form of dithizonate complex in CCl4. Au(III) ions were extracted by diethyl ether. The extracts were decomposed thermally. The dry residue was dissolved in the background electrolyte, and the element was determined by the SV method. The graphite electrode (GE) impregnated with polyethylene was used as a working electrode in SV–determination of silver. SV–determination of gold was carried out using GE modified by bismuth. The limits of detection (LOD) of Ag(I) and Au(III) contents were equal to 0.016 mg L-1 and 0.0086 mg L-1, respectively. The results of SV-determination of gold and silver in standard samples, pyrites and carbonaceous shales were presented. The silver content in the pyrite was 13.6 g t-1, in carbon shale—0.34 g t-1. The concentration of gold in the pyrite ore zone "Kirovsko–Kryklinskaya" was 1.15 g t-1; in carbonaceous shales—2.66 g t-1. The obtained data were consistent with the data of atomic emission spectroscopy (AES) and inductively coupled plasma mass spectrometry (ICP—MS). The error of determination of elements by stripping voltammetry was calculated when determining the silver content of 10...6 g t-1 in pyrite and carbonaceous material, which was less than 12%, and when determining the gold content of 1...3 g t- 1 in pyrite and carbonaceous matter, which was less than 23%.
PRÁTICAS CORPORAIS NA SAÚDE: POR UMA PEDAGOGIA DA DIFERENÇA NA APRENDIZAGEM DA SAÚDE E DA VIDA
Authors: Bueno Alessandra Xavier , Ferla Alcindo Antônio , Dessbesell Giliane
Published: December 2018

Ensaio teórico sobre a associação entre conhecimentos e práticas na saúde e da Educação Física e os efeitos pedagógicos para a afirmação do corpo como superfície na qual se inscreve a identidade contemporânea e parte dos padrões de saúde e performance física considerada normal. Na construção do artigo, mobiliza-se bases epistêmicas de produções selecionadas do campo da saúde coletiva e das ciências sociais e humanas que auxiliam na problematização das práticas vigentes e na proposição, a partir da ideia força da integralidade em saúde, uma pedagogia nômade e plural que se expressa no reconhecimento do corpo como singularidade e, sobretudo, na possibilidade de que assim seja constituído pelas lógicas do cuidado, com base na produção que se identifica como "práticas corporais", termo que carrega em si uma série de significados atrelados às singularidades das pessoas e que se legitima em um conjunto de outros conceitos advindo do campo das ciências humanas no interior de sistemas e serviços de saúde. Uma pedagogia que fortaleça/produza singularidades no corpo, colocando-o em movimento para a produção de saúde e autonomia no andar a vida, é proposta para o cuidado em saúde no encontro singular que o ensaio propõe para conhecimentos e práticas da saúde e da educação física.
DESENVOLVIMENTO DE EXERGAMES POR PROFESSORES NÃO PROGRAMADORES: UMA METODOLOGIA ATIVA DE APRENDIZAGEM PARA O AMBIENTE SCRATCH
Authors: Greis Luciano Kercher , Cardoso Fernando Luiz , Freitas Kamyla Thais Dias de
Published: December 2018

Apontado como recurso positivo, o uso de exergames no ambiente educacional encontra-se normalmente restrito a utilização de aplicações comerciais, ou ainda, ao complexo e nem sempre possível desenvolvimento de produtos por profissionais especializados. Contudo, a utilização de recursos tecnológicos acessíveis permite que professores de qualquer área e nível de ensino possam desenvolver de forma autônoma, exergames simplificados que atendam suas necessidades específicas. O objetivo deste artigo é descrever os pressupostos teóricos de uma metodologia que apoia-se nos conceitos construtivistas, partindo da utilização de um jogo de tabuleiro para capacitar profissionais de áreas que não ligadas a informática e programação, a expressar-se tecnologicamente criando exergames.
TECNOLOGIAS DE INFORMAÇÃO E COMUNICAÇÃO (TIC) E FORMAÇÃO DE PROFESSORES: INVESTIGANDO EXPERIÊNCIAS PEDAGÓGICAS MÍDIA-EDUCATIVAS NO CURSO DE PEDAGOGIA A DISTÂNCIA DA UNIVERSIDADE FEDERAL DE JUIZ DE FORA (UFJF)
Authors: Sousa Galdino Rodrigues de , Borges Eliane Medeiros
Published: December 2018

O texto é um segundo recorte de uma dissertação de mestrado que investiga a educação e as Tecnologias de Informação e Comunicação (TIC) no curso de Pedagogia a distância da Universidade Federal de Juiz de Fora (UFJF). Como instrumento de suporte de análise foi utilizada a mídia-educação e suas dimensões. A metodologia envolveu: a. uma parcela dos dados de uma primeira pesquisa, publicada por nós nessa mesma revista, referente a investigação curricular de duas disciplinas que tematizam as TIC no curso; b. comparação desses dados com as experiências pedagógicas desenvolvidas no Ambiente Virtual de Aprendizagem (AVA) desses dois componentes curriculares. Como resultado principal, percebemos que as práticas pedagógicas conseguiram ir além do que era previsto no currículo, contemplando outras dimensões e aspectos mídia-educativos.
A ESCOLA DE APRENDIZES MARINHEIROS NA CIDADE DO RIO GRANDE/RS (1861-1889)
Authors: Valle Hardalla Santos do , Amaral Giana Lange do
Published: December 2018

O presente trabalho tem o objetivo de abordar a instauração da Escola de Aprendizes Marinheiros na cidade do Rio Grande, nos anos de 1861 a 1889. São discutidos os princípios dessa instituição e suas ações de cunho correcional e de ensino de ofícios, destinados aos meninos desvalidos ou em situação de vulnerabilidade. Como alicerce teórico-metodológico utiliza-se a História Cultural, para a análise documental de decretos imperiais e dos jornais O tempo e Echo do Sul. Conclui-se que a disciplina e o ensino instaurados na instituição eram coerentes com a legislação e o contexto sociocultural vigente. Porém, a rigidez disciplinar aplicada aos meninos nem sempre promoveu os resultados esperados, esbarrando em ações de resistência.
Real-Time Foot Clearance Biofeedback to Assist Gait Rehabilitation Following Stroke: a Randomised Controlled Trial Protocol
Authors: Begg Rezaul , Galea Mary , James Lisa , Sparrow Tony , Levinger Pazit , Khan Fary , Said Catherine
Published: December 2018

Background: The risk of falling is significantly higher in people with chronic stroke and it is, therefore, important to design interventions to improve mobility and decrease falls risk. Minimum Toe Clearance (MTC) is the key gait cycle event for predicting tripping-falls because it occurs mid-swing during the walking cycle where forward velocity of the foot is maximum.
High forward velocity coupled with low MTC increases the probability of unanticipated foot-ground contacts. Training procedures to increase toe-ground clearance (MTC) have potential, therefore, as a falls prevention intervention. The aim of this project is to determine whether augmented sensory information via real-time visual biofeedback during gait training can increase MTC.
Methods: Participants will be over 18 years, have sustained a single stroke (ischaemic or hemorrhagic) at least 6 months previously, able to walk 50 metres independently and capable of informed consent. Using a secure web-based application (REDCap) 150 participants will be randomly assigned to either no-feedback (Control) or feedback (Experimental) groups, all will receive 10 sessions of treadmill training for up to 10 minutes at a self-selected speed over five to six weeks. The intervention group will receive real-time, visual biofeedback of MTC during training and will be asked to modify their gait pattern to match a required “target” criterion. Biofeedback is continuous for the first six sessions then progressively reduced (faded) across the remaining four sessions. Control participants will walk on the treadmill without biofeedback. Gait assessments are conducted at baseline, immediately following the final training session and then during follow-up, at 1, 3 and 6 months. The primary outcome measure is MTC. Monthly falls calendars will also be collected for 12 months from enrolment.
Discussion: This project will evaluate the impact of augmented sensory information, via visually presented biofeedback, for improving gait function in people with stroke. This has implications for the rehabilitation of gait disorders following stroke and may have the potential to reduce falls in this population.
Preoperative CT versus Intraoperative Hybrid DynaCT Imaging for Localization of Small Pulmonary Nodules: A Randomized Controlled Trial
Authors: Chao Yin Kai , Pan Kuang-Tse , Wen Chih-Tsung , Fang Hsin-Yueh , Hsieh Ming-Ju
Published: December 2018

Background
Small and/or deep pulmonary nodules have been traditionally localized using preoperative CT (POCT) imaging. However, the advent of hybrid operating rooms (ORs) has allowed intraoperative computed tomography (IOCT)-guided lesion localization. This single center, open-label, randomized, controlled clinical trial aims to compare the efficacy and safety of IOCT versus POCT.
Methods/design
The study sample will consist of patients presenting with small and/or deep pulmonary nodules who will be randomly allocated to either POCT or IOCT. The time required for identifying the lesion will be the primary efficacy outcome. The following parameters will serve as secondary endpoints: rate of successful targeting in the operating field, time at risk, complication (pneumothorax and hemorrhage) rates, and radiation exposure.
Discussion
Owing to the increased availability of HORs, our data will be crucial to clarify the feasibility and safety of IOCT versus the traditional POCT approach.
Modeling the Impacts of Manure on Phosphorus Loss in Surface Runoff and Subsurface Drainage
Authors: Wang Zhaozhi , Zhang T. Q. , Tan C. S. , Wang X. , Taylor R. A. J. , Qi Z. M. , Yang J. W.
Published: December 2018

Simulation of phosphorus (P) transfer from manured agricultural lands to water bodies via surface runoff and subsurface drainage is potentially of great help in evaluating the risks and effects of eutrophication under a range of best management practice scenarios. However, it remains a challenge since few models are capable of providing a reasonably accurate prediction of P losses under manure treatment. The Environmental Policy Integrated Climate (EPIC) model was applied to simulate the impacts on dissolved reactive P (DRP) losses through surface runoff and subsurface drainage from a solid cattle manure–amended corn (Zea mays L.)–soybean [Glycine max (L.) Merr.] rotation on a clay loam soil (Vertisol) located in the Lake Erie region. Simulations of DRP loss in surface runoff and tile drainage were satisfactory; however, EPIC did not consider DRP loss directly from manure, weakening its accuracy in the prediction of DRP loss in surface runoff. Having previously drawn on EPIC‐predicted surface runoff to initiate SurPhos (Surface Phosphorus and Runoff Model) predictions of DRP losses strictly in surface runoff, no comparison had been made of differences in manure application impacts on EPIC‐ or SurPhos‐predicted DRP losses—accordingly, this was assessed. The SurPhos improved the estimation of DRP loss in surface runoff (Nash–Sutcliffe coefficient, 0.53), especially when large rain events occurred immediately after or within 6 wk of manure application. Generally, EPIC can capture the impacts of manure application on DRP loss in surface runoff and subsurface drainage; however, coupling of the EPIC and SurPhos models increased the accuracy of simulation of runoff DRP losses.

Core Ideas

Simulations of DRP loss in surface runoff and tile drainage using EPIC were satisfactory.

Simulations of DRP loss in surface runoff between EPIC and SurPhos were compared.

Coupling SurPhos and EPIC improved surface DRP loss prediction with manure addition.
Understanding Critical Zone Evolution through Predicting the Three‐Dimensional Soil Chemical Properties of a Small Forested Catchment
Authors: Shepard Christopher , Schaap Marcel G. , Chorover Jon , Rasmussen Craig
Published: December 2018

Core Ideas

Used step function to predict three‐dimensional (3D) soil property distributions.

3D soil property distribution influenced by lithology and topography.

Profile reconstructions and digital soil mapping informed critical zone evolution.

Understanding critical zone evolution and function requires an accurate assessment of the distributions of its soil physical and chemical properties. Two‐dimensional (2D) digital soil mapping (DSM) provides a general understanding of soil characteristics across landscapes, but lacks the ability to predict soil properties with depth. Soil depth functions enable the reconstruction of soil properties with depth, potentially extending traditional DSM techniques to three dimensions (3D). We predicted the three‐dimensional soil chemical and physical properties of a small forested subcatchment of the Catalina‐Jemez Critical Zone Observatory using a combination of profile depth functions and traditional DSM techniques. The step function was used to reconstruct selected soil chemical and physical properties with depth for 24 described soil profiles. We compensated for uneven sampling depths by standardizing the profiles from 0.0 to 1.0, and splitting them into five equal standardized depth layers. Using available environmental covariates, step‐wise regressions were used to predict soil properties across the catchment. R2 values for the predictive functions ranged from 0.20 to 0.97 (p = 0.21 to <0.0001). Calcium and magnesium preferentially accumulated in channel drainages compared to potassium or sodium; this pattern corresponded with accumulation of clay in channel drainages. Parent material and sediment redistribution, driven by colluvial movement and hydrological flowpaths, were the main controls on the 3D soil chemical properties of the catchment. Combining depth functions with traditional DSM will provide more accurate assessments of soil spatial patterns across landscapes and with depth.
Exploring the Distribution of Zn2+ in Inner and Outer Helmholtz Planes of the Electrical Double Layer of Soil based on Wien Effect
Authors: Wang Yu-Jun , Fan Ting-Ting , Cui Pei-Xin , Alves Marcelo Eduardo , Li Cheng-Bao , Zhou Dong-Mei , Friedman Shmulik P. , Sparks Donald L.
Published: December 2018

Core Ideas

Wien effect measurements assess adsorbed cations distribution over the Helmholtz planes of the electrical double layer.

Assessing cation distributions in the electrical double layer improves bioavailability predictions for plant nutrients and pollutant metals.

Most of the zinc adsorption takes place in the inner Helmholtz plane layer and occurs via chemical interactions.

The classical electrical double layer (EDL) theory explains the interaction between ions and charged soil colloidal particles, playing an importance role in the bioavailability and toxicity of ions in soils, which are of agricultural and environmental concern. A new approach based on extrapolating measurements of suspension Wien effect is suggested to determine the adsorbed ions distribution in the different compartments of the EDL. The new approach was applied to assess Zn2+ distribution in the EDL of Zn‐saturated soil colloids. The results showed that more than 84% of Zn2+ was adsorbed via chemical interactions and located in the inner Helmholtz plane layer. The remaining Zn2+ fraction was electrically adsorbed and distributed in the outer Helmholtz plane layer (0.3 to 2.1%) and in the Gouy–Chapman diffuse layer (7.4 to 15.0%). Independently, the results of linear combination fitting of extended x‐ray absorption fine structure (EXAFS) spectra indicated that the contents of outer‐sphere Zn in one paddy soil and the boggy soil were consistent with the proportions of Zn2+ electrostatically interacting with the soil colloids based on the extrapolation of the suspension Wien effect method, while the contents of outer‐sphere Zn in a second paddy soil, the yellow cinnamon soil, and the yellow brown soil was overestimated by the EXAFS method. The approach proposed in this paper to assess specific and electrostatic adsorption deepens our understanding of metal sorption processes in soils and reinforces the adequacy of the Grahame–Stern–Gouy–Chapman model of the EDL to describe the ion distribution in the solid‐water interface.
TÜRKİYE’DE REKLAMLARIN DENETİMİ: REKLAM KURULU KARARLARI ÜZERİNDEN BİR İNCELEME
Authors: EŞİYOK Elif
Published: December 2018

Reklam sektör farkı olmaksızın, tüm kurum
veya kuruluşlar tarafından kullanılan bir pazarlama iletişimi bileşenidir.
Tüketicilerde belirli bir markaya ilişkin farkındalık sağlanması, ürün veya
hizmete ilişkin bilgilerin verilmesi ve tüketicilerin satın alma kararında
markaya ilişkin talebin oluşturulmasının sağlanmasında reklamların etkili
olduğu düşünülmektedir. Reklamlar birden fazla mecrada yayınlansa da, kitle
iletişim araçları en çok kullanılan mecraların başında gelir. Özellikle
geleneksel medya kapsamında yer alan televizyon, gazete ve dergiler reklam
verenler tarafından sıklıkla tercih edilen medya araçlarıdır. Reklamlar ile
ilgili olarak tüketicilerin korunması ve haksız rekabetin engellenmesi amacıyla
bir takım düzenlemeler yapılmıştır. Özellikle Reklam Kurulu bu konuda etkili
olan kurumların başında gelmektedir. Bu nedenle, bu çalışmada 2018 yılının ilk
6 ayındaki Reklam Kurulu kararları incelenmiş, Gümrük ve Ticaret Bakanlığı
Ticari Reklam ve Haksız Ticari Uygulamalar Yönetmeliği uyarınca yaptırım
uygulanan televizyon reklamları, yaptırım gerekçeleri ve verilen yaptırımlar
açısından irdelenmiştir. Çalışmada ayrıca adı geçen yönetmeliğe göre Kurul’un
yaptırım uygulama gerekçeleri ile
reklam etiği arasında nasıl bir bağ olduğu ortaya konulmaya çalışılmıştır.
Yapılan incelemeler sonucunda toplam 61 televizyon reklamının “doğruluk ve
dürüstlük”, “temel ilkeler” ve “ispat külfeti” maddelerine bağlı olarak idari
para cezası ve/ veya reklamları durdurma kararı aldığı saptanmıştır.
İZLEK BAĞIMLILIĞI TEORİSİ VE YAPAY ZEKÂ TEKNOLOJİSİNE GEÇİŞ: HİZMET ENDÜSTRİSİ ÜZERİNE BİR ANALİZ
Authors: TEKİN BİLBİL Ebru
Published: December 2018

Bu çalışmanın amacı, yapay zekâ teknolojisinin
getireceği değişim, yenilik ve dönüşüm süreçlerinin ilk evrelerinde ortaya
çıkan tedirginliğin oluşturucu dinamiklerini, sebeplerini ve aynı zamanda
beklentileri, algıları ve kısıtları araştırmaktır. Bu teknolojinin henüz
tarihsel bir geçmişi olmadığından, bu makale izlek bağımlılığı teorisinin
evrimsel ve dizileme analizlerinden ziyade, artan geri dönüşler analizine
odaklanmaktadır. Bu çalışma araştırma bulgularını üç açıdan analiz etmektedir:
(1) Teknoloji, yenilikler ve teknolojik değişim; (2) Geçmiş bilgi ve bilgi
tabanı, geçmiş tecrübeler, izlenimler, kültür, algılar, tercihler ve yetiler;
(3) Rutinler ve rutinler bütünü ile düzenli işleyen ve kurumu mevcut izlekte
tutan işler ve süreçler. Çalışma şu sorun alanları ortaya tanımlamaktadır: (1)
Sanayi 4.0 hakkında bilgi eksikliğinin söz konusu olması, (2) Değişimin nasıl
ve ne biçimde olacağının öngörülememesi, (3) Uyum problemleri, (4) Altyapısal
problemler, (5) Yeni teknolojinin maliyeti, (6) Aktörlerin yeni teknolojiye
geçişte istek ve niyetleri, (7) Çalışanları yapay zeka ve büyük veri üzerine
eğitime ihtiyacı.
Effect of photochemical advanced oxidation processes on the formation potential of emerging disinfection by-products in groundwater from part of the Pannonian Basin
Authors: Jazić Jelena Molnar , Agbaba Jasmina , Tubić Aleksandra , Watson Malcolm , Đurkić Tajana , Krčmar Dejan , Dalmacija Božo
Published: December 2018

This study evaluates the effect of photochemical advanced oxidation processes (AOPs) (O3/UV, H2O2/UV and O3/H2O2/UV) on the formation potential (FP) of emerging disinfection by-products including nitrogenous by-products (N-DBPs) and haloketones (HKs) in groundwater from part of the Pannonian Basin (AP Vojvodina, Republic of Serbia). Among the N-DBPs, the haloacetonitrile (HAN) precursor contents were 9.83 ± 0.59 μg/L while precursors of halonitromethanes, particularly trichloronitromethane (TCNM) were not detected. Similarly, precursors of HKs as carbonaceous DBPs were also not detected in raw water. Ozonation alone and the H2O2/UV process with a lower UV dose maximally decomposed HAN precursors (about 70%) while during O3-based AOPs, HANFP varied significantly. Application of UV photolysis and H2O2/UV processes with increasing UV dose doubled the HANFP. Ozone alone, O3/UV and H2O2/UV slightly increased HK formation potential, particularly 1,1-dichloro-2-propanone FP (0.93 ± 0.21 to 2.01 ± 0.37 μg/L). None of the investigated treatments influenced the formation of TCNM precursors. The effect of the applied treatments on bromide incorporation was most evident for HANs.
Development and Characterization of Olanzapine Loaded Poly(lactide-co-glycolide) Microspheres for Depot Injection: In vitro and In vivo Release Profiles
Authors: Pervaiz Fahad , Ahmad Mahmood , Li Lihong , Murtaza Ghulam
Published: December 2018

Purpose:

The purpose of this study was to develop a new PLGA based microsphere formulation aimed to release the olanzapine for the period of one month which will result in increased compliance.

Methods:

Microspheres loaded with olanzapine were prepared using oil in water emulsion and solvent evaporation technique. The microspheres were characterized by surface morphology, shape, size, bulk density, encapsulation efficiency, and Fourier transform infrared spectrometry. In vitro release studies were performed in phosphate buffer at 37°C and in vivo studies were conducted on male Sprague- Dawley rats.

Results:

The morphological results indicated that microspheres produced were having a smooth surface, spherical shape and the size in the range from 9.71 to 19.90 μm mean diameter. Encapsulation efficiency of olanzapine loaded microspheres was in the range of 78.53 to 96.12% and was affected by changing the ratio of lactic to glycolic acid in copolymer PLGA. The properties of PLGA and other formulation parameters had a significant impact on in vitro and in vivo release of drug from microspheres. In vitro release kinetics revealed that release of drug from microspheres is by both non-Fickian diffusion and erosion of PLGA polymer. In vivo data indicated an initial burst release and then sustained release depending on properties of PLGA, microsphere size, and bulk density.

Conclusion:

This study indicates that microsphere formulations developed with PLGA (75:25) and PLGA (85:15) have provided a sufficient steady release of drug for at least 30 days and can be potential candidates for 30-day depot injection drug delivery of olanzapine.
Probucol Self-Emulsified Drug Delivery System: Stability Testing and Bioavailability Assessment in Human Volunteers
Authors: Zaghloul Abdelazim , Lila Ahmed , Abd-Allah Fathy , Nada Aly
Published: December 2018

Background:

Self-Emulsifying Drug Delivery System (SEDDS), if taken orally, is expected to self-emulsify in GIT and improve the absorption and bioavailability. Probucol (PB) is a highly lipophilic compound with very low and variable bioavailability.

Objective:

The objectives of this study were to examine the stability and conduct bioavailability of the prepared Probucol Self-Emulsified Drug Delivery System (PBSEDDS) in human volunteers.

Methods:

The methods included preparation of different PBSEDDS using soybean oil (solvent), Labrafil M1944CS (surfactant) and Capmul MCM-C8 (co-surfactant). The formulations were characterized in vitro for spontaneity of emulsification, droplet size, turbidity and dissolution in water after packing in HPMC capsules. The optimized formulations were evaluated for stability at different storage temperatures and human bioavailability compared with the drug dissolved in soybean oil (reference).

Results:

The results showed that formulations (F1-F4) were stable if stored at 20 °C. The mean (n=3) pharmacokinetic parameters for stable formulations were: The Cmax, 1070.76, 883.16, 2876.43, 3513.46 and 1047.37 ng/ml; the Tmax, 7.93, 7.33, 3.96, 3.67 and 4.67 hr.; the AUC (0-t), 41043.41, 37763.23, 75006.26, 46731.36 and 26966.43 ng.hr/ml for F1, F2, F3, F4 and reference, respectively. The percentage relative bioavailability was in this order: F3> F4> F1> F2>.

Conclusion:

In conclusion, the PBSEDDS formulations were stable at room temperature. F4 showed the highest Cmax and the shortest Tmax. All the formulations showed significant enhancement of bioavailability compared with the reference. The results illustrated the potential use of SEDDS for the delivery of probucol hydrophobic compound.
Bibliometrics of CNS & Neurological Disorders – Drug Targets: An International Evolution Along Time
Authors: Medeiros Mirna Rossi Barbosa , de Mello Alves Rodrigues Ana Carolina , Alves Mariana Rocha , Silva Roberto Cesar Faria e , Felício Lais Francielle Francisca , Carneiro Lara S.F. , Fagundes Daniel Ferreira , Machado Sérgio , Monteiro-Junior Renato Sobral
Published: December 2018

Objective and Method:

To investigate trends in the scientific evolution of the journal CNS
& Neurological Disorders - Drug Targets in the neuroscience scope, we compared the contribution of
publications between this journal and others from different geographical regions of the world. To track
research output we conducted a bibliometric analysis of neuroscience research based on the SCimago
Journal and Country Rank® from 2003 to 2017. Journal rankings were verified according to the following
inclusion criteria: journals publishing the neuroscience scope and sub-areas; geographical location
and journal trajectory. Additionally, the total number of original, peer-reviewed and conference
articles was analyzed using bibliometric tools.

Results:

Results showed that Europe, North America and the Middle East have been the greatest contributors
of neuroscience publications. Nevertheless, there is a huge discrepancy in the number of
journals per region. Until 2017, Europe was on top with 85 journals in the neuroscience field. Moreover,
research on neuroscience displayed a swift expanding trend, with significant growth in recent
years.

Conclusion::

In spite of CNS & Neurological Disorders - Drug Targets being a recent journal, it is an
international journal emphasizing quality and innovations, and it is a hallmark on the scientific production
in neuroscience. Research articles on the scope of the potential role of endocannabinoid systems
in central appetite control and in obesity management and the potential of minocycline use in
schizophrenia are paramount examples of innovation. Final results will help scientific researchers to
know the current interests in neuroscience and provide useful information for further investigation and
publication strategies.
Vitamin D and Type I Diabetes
Authors: Savastio Silvia , Cadario Francesco , Beux Sheila , Giorgis Alberto , Genoni Giulia , Bagnati Marco , Bellomo Giorgio , Bona Gianni , Maiuri Luigi
Published: December 2018

Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism but is also endowed with the capability of modulating inflammatory and immune function. Recent studies reported a relationship between low vitamin D levels and several autoimmune diseases such as Type 1 Diabetes. Vitamin D regulates the expression of over 200 genes, also related to immune modulation, suggesting a putative role in these diseases pathogenesis. This review overviews the most recent advances on the association between vitamin D and increased risk of Type 1 Diabetes as well as between vitamin D and either glucose homeostasis or insulin sensitivity. The effects of vitamin D in modulating the immune response and balancing anti-inflammatory cytokines, suggest that vitamin D system may represent an unforeseen target for the design of novel strategies for the treatment of patients with autoimmune diseases and in particular Type 1 Diabetes.
An Accurate Drain Current Model for Symmetric Dual Gate Tunnel FET Using Effective Tunneling Length
Authors: Sahoo Sasmita , Dash Sidhartha , Mishra Guru P.
Published: December 2018

Introduction:

Here we propose an accurate drain current model for a Symmetric Dual
Gate Tunnel FET (SDG-TFET) using effective tunneling length and generation rate of carrier over
tunneling junction area.

Analytical Modeling:

The surface potential of the model is obtained by solving 2-dimensional
Poisson’s equation and further extends to determine the magnitude of initial tunneling length and
final tunneling length. The different DC performance indicators like drain current (ID), threshold
voltage (Vth), transconductance (gm) and Subthreshold Slope (SS) for the present model are extensively
investigated and the results are compared with that of Single Gate Tunnel FET (SGTFET).

Conclusion:

The practical importance of this model relies on its accuracy and improved electrostatic
performance over SG-TFET. The analytical model results are validated using TCAD Sentaurus
(Synopsys) device simulator.
Результати наукових досліджень найбільш істотних факторів ускладненого перебігу періоду гестації у жінок України
Authors: Zhabchenko I. , Pisareva S. , Shamayeva O.
Published: December 2018

У статті відображені дані аналізу статистичних матеріалів МОЗ України щодо перебігу та результатів закінчення вагітностей у жінок України за 2008-2009 рр. Проаналізовано якість антенатального нагляду за вагітними в Україні у цей період, зроблено висновки щодо найсуттєвіших чинників ускладнень вагітності та пологів та визначено подальший напрямок досліджень щодо їх подолання та попередження.
Современное состояние дельфинотерапии (обзор литературных и собственных данных)
Authors: Chuprikov A. , Popovskiy B. , Shypelik T.
Published: December 2018

В статье представлен обзор литературных и собственных данных по использованию дельфинотерапии в детской неврологии. Являясь новым для современных детских психиатров методом реабилитации, дельфинотерапия привлекает все больше внимания не столько специалистов, сколько родителей больных детей. Благодаря их настойчивости она заняла прочное место среди вспомогательных методов, дополняющих комплексную терапию детского аутизма, психоорганического расстройства, задержки психоречевого развития, умственной отсталости и других состояний. Авторы, высказывающие сомнения в доказательности терапевтического действия метода, не знакомы с соответствующей русскоязычной литературой. По мере дальнейшей гуманизации психиатрии дельфинотерапия, как один из методов анималотерапии, займет подобающее место среди способов психосенсорной интеграции развивающегося мозга.
Оценка нейрогуморальных факторов, влияющих на сосудистый тонус у лиц молодого возраста, работающих в ночное время суток
Authors: Zarubina E. , Aseyeva E. , Turkovskiy J. , Moiseyeva T.
Published: December 2018

В статье представлен анализ распространенности заболеваний сердечно-сосудистой системы у лиц в возрасте от 21 до 36 лет, работающих в ночное время суток. Проведена клиническая оценка вегетативного дисбаланса у исследуемых групп лиц. С помощью клинико-лабораторного метода в данной работе изучены особенности гуморальной регуляции тонуса сосудов у лиц молодого возраста с различной сердечно-сосудистой патологией, в зависимости от продолжительности посменного ночного характера труда, проведена оценка уровня гормонов стресса при различных сердечно-сосудистых заболеваниях. Выявлена и фактически доказана взаимосвязь нарушения нейрогуморальной регуляции сосудистого тонуса с развитием патологии сердца и сосудов у молодых людей при нарушении ритмов труда и отдыха.
Швидкі тести та їх місце в етіологічній діагностиці гострих кишкових вірусних інфекцій
Authors: Dzyublyk I. , Samborska I. , Solovyov S.
Published: December 2018

Початок нового ХХI століття характеризується невпинним зростанням ролі вірусів в інфекційній патології людини. Ротавіруси (РВ) і норовіруси (НВ) людини претендують на лідерські позиції серед збудників гострих кишкових інфекцій (ГКІ) вірусної природи. Найбільшу небезпеку ці інфекції представляють для дітей перших років життя і людей похилилого віку, бо мають високі показники захворюваності і летальності. НВ спричинюють до 90 % спалахів серед дітей та дорослих в різних країнах світу. Мета роботи полягала у вивчення ефективності застосування швидких тестів (ШТ) на основі імунохроматографічного аналізу (ІХА) порівняно з імуноферментним аналізом (ІФА) та полімеразною ланцюговою реакцією (ПЛР) для етіологічної діагностики НВІ. Лабораторним обстеженням та клінічним спостереженням було охоплено 569 дітей та дорослих з діагнозом ГКІ. Визначення антигенів НВ здійснювали ІХА-тестами та методами ІФА і ПЛР. Вдосконалення технологій виробництва ШТ для етіологічної діагностики ГКІ призвело до того, що їх чутливість та специфічність не поступаються відповідним показникам тест – систем для ІФА, що підтверджено нашою роботою. Такі характеристики надають можливість розглядати ці тести як альтернативу іншим методам лабораторної діагностики для швидкого визначення збудника інфекції при встановленні клінічного діагнозу в осередках спалахів ГКІ та своєчасного проведення відповідних протиепідемічних заходів. Особливо важливо підкреслити доцільність, зручність, простоту виконання ШТ при застосуванні в практичній роботі сімейного лікаря для достовірної діагностики ГКІ, а отже, своєчасного встановлення правильного діагнозу та призначення адекватної та ефективної терапії.
Фасилитационный аспект деятельности по оздоровлению
Authors: Skomorovskiy Yu.
Published: December 2018

Важнейшей функцией валеологической деятельности по оздоровлению является фасилитация. Впервые классический эффект фасилитации (улучшение индивидуального результата за счет присутствия другого человека) был обнаружен в исследованиях Н. Триплета. Наиболее общий взгляд на природу явления фасилитации, на собственную жизнь и здоровье превращает специалиста, а затем и пользователя его услуг во внешнего наблюдателя по отношению к себе же, своей жизни и здоровью.
Деякі фінансово-економічні аспекти реформування охорони здоров’я України
Authors: Trofymenko S. , Tomynets` A. , Shekera O.
Published: December 2018

У статті висвітлюється стан реформування охорони здоров’я України, зокрема, зосереджено увагу на проблемі фінансового забезпечення галузі та розглядаються основні заходи, які здійснюються державою для вирішення цієї проблеми.
Оптимізація післядипломної підготовки медичних працівників з питань надання паліативної та хоспісної допомоги населенню в умовах реформування системи охорони здоров’я України
Authors: Tsarenko A. , Gubskiy Yu. , Shekera O.
Published: December 2018

У статті представлені сучасні підходи і методи, а також міжнародний досвід професійної післядипломної підготовки медичних працівників з питань надання паліативної та хоспісної допомоги населенню, що набуває в умовах реформування системи охорони здоров'я в Україні особливого значення. Показано, що оптимізація післядипломної професійної підготовки медичних працівників з питань паліативної та хоспісної допомоги має велике значення для забезпечення високої якості надання медичної допомоги населенню і вимагає в процесі безперервної післядипломної освіти залучення викладачів різного профілю, що довело свою ефективність на кафедрі паліативної та хоспісної медицини НМАПО імені П.Л.Шупика.
Гостра ревматична лихоманка: сучасний погляд на проблему
Authors: Himion L.
Published: December 2018

В статті наведено огляд сучасних рекомендацій та розглянуто проблемні питання діагностики, профілактики і лікування гострої ревматичної лихоманки.
Hubungan Pemakaian Alat Kontrasepsi Dalam Rahim (AKDR) Non Hormonal dengan Kejadian Vaginitis
Authors: Sari Eka Mega , Prawitasari Shinta , Attamimi Ahsanudin
Published: December 2018

Background: Colonies of microorganism in reproductive normal women vaginal is influenced by several factors. Changes in the composition of these factors cause of some problems such as infection and inflammation. The use of intrauterine devices could be expected to lead to vaginitis.Objective: To determine whether the use of intrauterine device increase the incidence of vaginitis, either by Bacterial Vaginosis (BV), Vulvovaginal Candidiasis (VVC), and Trichomonas Vaginalis (TV) .Method: Cross Sectional Study on the differences incidence of vaginitis in intrauterine device user and hormonal user.Result and Discussion: At the intrauterine devices and hormonal contraception users, there are significant difference incidence of BV (OR 10,11;95% CI 1,80-56,78) ; p=0,009 (p<0,05) dan VVC (OR 29,78 (1,64-2540,69); p=0,022 (p<0,05), but not TV (OR 3,68;95% CI 0,11-117,63); p=0,460 (p>0,05).Conclusions: The use of an intrauterine device increase the incidence BV and VVC but not  TV.Keywords: Intrauterine Device; Hormonal Contraception; Vaginitis
The Role of Health Researchers in Documenting Health Suffering and Crimes against Humanity Resulting from 2018 US Sanctions against Iran
Authors: Gibson Ruth Margaret
Published: December 2018

On November 20, 2018, the United States imposed unilateral sanctions on the Republic of Iran. The intention of these sanctions, which are being used in conjunction with other political pressures, is to impose financial hardship on Iran for its perceived support of Syrian president Bashar al-Assad and terrorism. The consequences of these sanctions for the Iranian population will be manifold, with health likely to be one of the first sectors to suffer. There is no designated international body responsible for monitoring population health in the wake of sanctions; thus, health researchers have a pivotal role to play in the international community. The timely collection of health data can supply bodies such as the United Nations Security Council with information about the justness of the US sanctions and can be used in making arguments to protect human rights, including health, and in preventing crimes against humanity. This article briefly explains the concept of crimes against humanity and how health data and health service researchers can play an important role in drawing attention to declining health indicators in a sanctioned country.