bluuebunny/crossref_metadata_2025 huggingface dataset:
SugarMumma: The Development of a Smartphone App for Women living with Gestational Diabetes Mellitus (Preprint)
Authors: Knight-Agarwal Catherine , Bushell Mary Jess , Hooper Mary-Ellen , JoJo Natasha , Atchan Marjorie , Shield Alison , Douglas Angela , Saleh Abu , Mohammadian Masoud , Khan Irfan , Chan Cheuk , Rovira Iturrieta Nico , Murphy Emily , Arza Tanishta , Davis Deborah
Published: August 2024

BACKGROUND

Gestational Diabetes Mellitus (GDM), a type of blood glucose intolerance or hyperglycemia that occurs during pregnancy, is a common condition increasing in prevalence both globally and in Australia. Mobile health applications have been shown as a useful resource for women with Type 1 diabetes and could successfully contribute to GDM management by facilitating healthy behaviors.

OBJECTIVE

To seek the perspectives of Health Care Consumers (HCCs) and Health Professionals (HPs) regarding the development of a smartphone application for women living with GDM.

METHODS

A co-design process with four distinct phases and using an evidence-based approach underpinned the development of the SugarMumma App. Existing evidence, and the results from interviews and focus groups with eight stakeholders created an initial set of recommendations. An app development company designed the prototype with HCCs and HPs undertaking ‘user acceptance testing.’ Analysis of the findings from a second round of interviews was undertaken.

RESULTS

Data analysis revealed four themes. Functionality, Communication, and Individualised care were recognised as being pivotal if the app was to be informative and useful in addition to supporting the diverse needs of HCCs. Motivation to manage GDM and birth a healthy baby was seen as a motivating factor for SugarMumma’s use by women.

CONCLUSIONS

With increasing numbers of people using smartphones in their daily lives, mHealth apps can help manage chronic conditions such as GDM. Good functionality, regular notifications, appealing visual aids, positive feedback, relevant dietary advice and exporting information to HPs are important features to include.
Prevalence of post-covid complications in a follow-up survey of participants of two Homoeopathy-based RCTs on moderate and severe cases of COVID-19: A cross-sectional study (Preprint)
Authors: Kaur Harleen , Bawaskar Ramesh , Chatterjee Tania , Singh Gurpreet , Bajpai Anurag , Singh Shweta , Bhogal Twinkle Kaur , Khan Mohammed Yamin , Ramteke Sunil S. , Kaushik Subhash
Published: August 2024

BACKGROUND

Coronavirus disease 2019 (COVID-19) was declared a global pandemic by WHO on 11th March 2020. Witnessing the pattern of relapse of cases, varying severity of cases and persistence of symptoms through different waves of pandemic has emerged as the reason for the studies targeting post-covid status of individuals.

OBJECTIVE

The objective of this survey was to assess the long-term effectiveness of homoeopathic medicines when used as an adjunct therapy along with the conventional therapy during covid infection in oxygen-dependent, moderate and severe patients.

METHODS

The survey was carried out from 1st April 2022 to 29 May 2022 via telephonic conversation among 219 participants who were discharged from AIIMS, Jhajjar, Haryana and St. George Hospital, Mumbai, India and had participated in two different placebo-controlled, randomised trials held at these two hospitals where individualised homoeopathic medicines were given to the experimental groups in addition to the conventional treatment. The post-COVID-19 Functional Status (PCFS) Scale was employed to evaluate the functional status of the surviving survey participants and to compare the status between the add-on Homoeopathy (AoH) group and the add-on placebo (AoP) group.

RESULTS

The mean score of PCFS Scale between the groups were compared using the chi-square test, which was presumed to be statistically significant at P<0.05. In total, 93 participants of AoH group showed more functional ability with mean difference of 0.83±1.47 (mean ± SD), as opposed to 1.33±1.63 (mean ± SD) among the AoP group participants (P=.04). Percentage of participants who developed post-COVID diabetes mellitus or hypertension, or shortness of breath on exertion and was found to be 17.20%, 8.60% and 6.45%, respectively in the AoH group, as compared to 17.57%, 9.68% and 10.81%, respectively in the AoP group. No incidence of post covid anxiety, pneumonia and chronic/acute kidney disease was reported in the AoH group while it was 1.35%, 1.35% and 4.05% respectively in the AoP group. The ability to perform daily chores was observed to be in 57% of the participants of AoH group, as against 43% of those in the AoP group.

CONCLUSIONS

Homoeopathy, when given as an add-on therapy in COVID-19, helps in faster recovery from acute infections such as COVID19, with a higher proportion of participants being able to perform daily chores, along with an improvement in their general weakness, even after the medicine was discontinued. This proved the long term effectiveness of homoeopathic treatment when used as an adjunct therapy along with the conventional therapy in the oxygen-dependent, moderate or severe patients of COVID-19.

CLINICALTRIAL

As it was a survey, trial registration is not mandatory.
Global trends and hotspots of the digital therapeutics in rehabilitation: A bibliometric analysis. (Preprint)
Authors: Ma Run Ting , Chen Yuan , Song Huiyan , Wei Yixin , Zhang Li , Gao Qiang
Published: August 2024

UNSTRUCTURED

Background: Digital therapeutics (DTx) are emerging as a dynamic field at the intersection of healthcare and technology, utilizing software-driven interventions to prevent, manage, or treat medical conditions. Within rehabilitation, DTx has gained prominence for its potential to improve patient outcomes and refine therapeutic strategies. This paper conducts a bibliometric analysis of existing literature to uncover current research trends and offer insights for future investigations.
Methods: The Science Citation Index Expanded database from the Web of Science Core Collection was used to retrieve articles and reviews related to digital therapeutics in rehabilitation. The data were subjected to systematic analysis using the VOSviewer and Citespace software tools, which facilitated the examination of publication data at the country, institutional, author, journal, citation, and keyword levels.
Results: A total of 6,593 papers published between 2000 and 2024 were reviewed. The volume of publications has steadily increased over the past two decades, reaching a peak in 2022 (n = 832). Leading contributors to research output and citation impact include the USA, Italy, China, Canada, and England. Current research hotspots include the efficacy of DTx in rehabilitation, with a focus on innovative applications in psychiatric disorders, telerehabilitation, and cognitive rehabilitation. The top 10 researchers were all from Italy, and half of them were affiliated to the Centro Neurolesi Bonino Pulejo Messina, and all had higher citations than those from other Italian organisations.
Conclusions: This study represents the first comprehensive bibliometric analysis of DTx within the rehabilitation field. It identifies current research frontiers and emerging directions, serving as a valuable resource for scholars and researchers investigating DTx's impact on rehabilitation practices.
Generating a Benzodiazepine Taper Using a Large Language Model: Feasibility Study (Preprint)
Authors: Ekekezie Obinna
Published: August 2024

UNSTRUCTURED

Exploring the feasibility of using artificial intelligence (AI), specifically large language models (LLMs), to automate the generation of benzodiazepine tapering plans.
Review of Translation Teaching for Postgraduates of Non-English Majors (2003-2023)
Authors: Hu Zhongqing , Cui Yan
Published: August 2024

As international exchange continues to expand and intensify, E-C (English-Chinese) translation teaching for postgraduates of non-English majors, aimed at nurturing interdisciplinary talents equipped with both professional knowledge and pragmatic competence, has garnered widespread attention. Domestic scholars have explored the aspects of “teaching” and “learning” in E-C translation teaching for postgraduates of non-English majors from multiple dimensions. This paper reviews E-C translation teaching for postgraduates of non-English majors in China in the past two decades based on representative studies, sorts out the focus and current status of research, and looks forward to the future development of teaching practice. We found that universities generally advocate and adopt interdisciplinary teaching methods that integrate “foreign language” into “majors”, and E-C translation teaching for postgraduates of non-English majors also revealed aspects that urgently need to be improved. Therefore, reviewing and reflecting on research related to translation teaching and proposing targeted measures based on its current teaching challenges have extremely important theoretical and practical significance.
Research on the Development of Traditional Handicraft Industry in Heqing County Based on the SWOT-PESTEL Model
Authors: Li Zefeng
Published: August 2024

The traditional handicraft industry in Heqing County embodies rich ethnic culture and history, particularly the art of silver jewelry craftsmanship, which has been recognized as a national-level intangible cultural heritage, holding significant cultural and economic value. Nevertheless, the industry still faces challenges brought about by modernization and globalization, such as the disruption of skill inheritance, fluctuating market demand, and intensified market competition. This study employs the SWOT-PESTEL model to analyze the strengths of Heqing County’s handicraft industry in terms of policy support, cultural resources, and geographical advantages, while also identifying weaknesses including insufficient technological innovation, low industrial concentration, and a shortage of talent. To promote sustainable development, it is recommended to enhance policy implementation, cultivate leading enterprises, drive technological innovation, deepen the integration of cultural tourism, strengthen talent development, and raise environmental awareness. These strategies aim to provide theoretical support and practical guidance for the development of the traditional handicraft industry not only in Heqing County but also in other regions, thereby promoting the inheritance and innovation of Local traditional handicraft culture.
Examining the Social Consequences of Automation and Artificial Intelligence in Industrial Management
Authors: Taleghani Mohammad , Sola Mohammadreza Jabreilzadeh
Published: August 2024

This article examines the social consequences of automation and artificial intelligence (AI) in industrial management, drawing on the findings of Damioli, Van Rooy, and Vertsy’s (2021) study on the impact of AI on labor productivity. The integration of AI technologies in industrial settings has led to significant improvements in efficiency and productivity. However, these advancements come with substantial social implications that affect both the workforce and broader societal structures. Internally, automation and AI have shifted the demand from low-skilled to high-skilled labor, necessitating ongoing education and skill development for employees. Additionally, the reliance on AI for managerial decisions raises ethical concerns regarding algorithmic biases and the potential erosion of human judgment.Externally, the broader societal impact includes economic disparities, as regions with a high concentration of low-skilled jobs experience greater unemployment and underemployment. The displacement of workers due to automation presents challenges such as increased socio-economic divides and disruptions to community stability. Ethical considerations, including data privacy and security, are crucial to ensuring fair and responsible AI deployment. This article underscores the need for strategic collaboration between industry leaders, policymakers, and educational institutions to address these social consequences. By fostering an inclusive approach to technological advancement, it is possible to balance the productivity benefits of AI with the imperative to mitigate its adverse social impacts.
Morpho-biochemical parameters in blackgram (Vigna mungo L. Hepper) genotypes under drought stress condition
Authors: Joshi G. Kumara , Naik K. Srinivas , Nayak Bhattu Rajesh , Yugandhar.A Yugandhar.A , Kumar G.Vijay
Published: August 2024

The present study carried out with ten blackgram accessions collected from NBPGR regional centre and T-9(Check) from ICAR-CRIDA, Hyderabad. The experiment was conducted in experimental farm, Department of Genetics, Osmania University Hyderabad during Rabi,2021. The ANOVA results revealed that for treatments all the yield,physiological and biochemical parameters were showed significant variability except 100 seed weight. All the yield and physiological parameters were significant for genotype x treatment except number of branches per plant and canopy temperature. The character seed yield (g/pl) was observed under irrigated condition highest by IC436524 and lowest by T-9. Whereas highest seed yield (g/pl) was observed under drought condition by IC426766. It was also observed that the genotype IC426766 28.84% over its control and 37.65% over T-9 under drought condition. The genotype IC426766 also showed higher proline content, RWC, lower MDA, higher SPAD reading and lower canopy temperature under drought condition. Among ten blackgram accession IC 426766 was identified as drought tolerant/resistance based on morphological, physiological and biochemical parameters.
An Economic Analysis of Organic Farming for Sustainable Agriculture and Facing the Constraints by Organic Farmers of Uttarakhand
Authors: Shukla Dr. Awadhesh Narayan , Narain Dr. Sarju , Tripathi Dr. Ajay Kumar
Published: August 2024

Introduction: Agriculture is carried out mainly through three types of farming systems namely, natural farming system, inorganic farming system and organic farming system characterized by the different types of inputs and agricultural management practices used for cultivation of land and production of crops. Context: Green revolution brings several changes in agriculture production system via inorganic farming which promotes unsustainable practices for ecosystem and human health. Therefore organic farming practices are more prefer by farmers for obtaining better price. Objectives: In this context it is necessary to find out the economics of major crops grown under Organic Farming System and identify the constraints of production in hilly region of Uttarakhand as compare to Inorganic friendly farmers. Method: A purposive study was conducted in district Tehri - Garhwal and Almora under hill state of Uttarakhand. The result is based on the randomly selected 120 farmers (60 Organic Farming System Farmers and 60 Inorganic Farming System Farmers) interview. The costs of production of different crops have been worked out by using the standard cost concepts with suitable statistics. Results & Discussion: The gross as well as net income or profit of different crops increased significantly by two to three times under organic farming system whereas they remained stagnant and even declined under inorganic farming system over the years. The costs of production of crops per hectare and per quintal under organic farming system are lower than under inorganic farming system. Gross and net incomes or profits are nearly 2 times higher under organic farming systems. Overall organic farming system produces more and sustainable agriculture output with less energy, low cost and fewer resources with many constraints.
Competencies of Marine Engineering Students of a Maritime Higher Education Institution: An Assessment
Authors: Derecho Rio Henson Liwag
Published: August 2024

Competency assessment plays a critical role in determining the proficiency and effectiveness of future marine officers. The competence of marine engineering students focusing on their performance, the perceived factors that affect their competency, and the challenges they met during practical assessment were assessed. Using quantitative descriptive design, a practical assessment using the adopted practical assessment from the Maritime Administration and a survey questionnaire were used to achieve the research objectives. Total enumeration of the 30 marine engineering students and ten engine instructors who handle laboratory courses were the participants and respondents. Results include the general exemplary performance of the participants except in Function 2; several factors affect the students’ performance, such as student-related factors, instructor-related factors, facilities and equipment, and policy-related factors; and 46 challenges were identified. Several recommendations were presented. Among them are the incorporation of more simulation-based training that presents real-life scenarios requiring quick and effective decision-making; use of mnemonics memory aids; digital versions of learning materials for easy access; provision of scholarship grants, and others.
Alfabetización financiera y ahorro para el retiro de los mexicanos durante la pandemia de Covid-19
Authors: Moreno-García Elena , Hernández-Mejía Sergio
Published: August 2024

Esta investigación tiene como objetivo analizar como cambió el ahorro para el retiro de los mexicanos durante el periodo de pandemia y determinar si el cambio estuvo en función de su nivel de alfabetización financiera, su educación financiera y sus características socioeconómicas y demográficas. Se estima un modelo Logit multinomial con datos de la Encuesta Nacional de Inclusión Financiera correspondientes a 2021 y 2018. Los resultados evidencian un aumento significativo del 5.76% de personas que ahorraron de manera formal para el retiro en el 2021 con respecto al 2018 y una disminución de 3.91% de los que ahorraron de manera informal, así como del incremento de la probabilidad de ahorrar para el retiro de manera formal y la disminución de la probabilidad del ahorro informal y del no ahorro en el mismo período. Se tiene evidencia que apoya las hipótesis del efecto positivo y significativo de la alfabetización financiera y la educación financiera sobre el ahorro para el retiro. A excepción de tener una cuenta sofisticada, el cambio en el ahorro para el retiro sucede en función de las características socioeconómicas y demográficas.  Los resultados remarcan la importancia que tienen la alfabetización y la educación financieras en la capacidad de las personas para afrontar la incertidumbre generada por una crisis como la de pandemia de COVID-19.
Liderazgo ético y teletrabajo; el rol mediador de la autonomía laboral, la autoeficacia y un clima ético benevolente
Authors: Santiago-Torner Carlos
Published: August 2024

El propósito de este estudio es determinar cómo el liderazgo ético influye sobre el teletrabajo y si la autonomía laboral, la autoeficacia y un clima ético benevolente explican esta asociación. El objeto de la investigación es el Sector Eléctrico Colombiano. La muestra está constituida por 273 hombres y 175 mujeres con estudios universitarios, el análisis estadístico se realiza a través de un proceso de mediación múltiple. Los resultados muestran que el liderazgo ético se relaciona proactivamente con los beneficios potenciales del teletrabajo a través del efecto causal de las tres variables mediadoras. El líder ético transfiere confianza, equilibrio y apoyo lo que repercute en la capacidad del seguidor para utilizar sus criterios de forma autónoma y afrontar obstáculos con una alta autoeficacia. Asimismo, el líder ético cuando progresa a través de un clima que tiene como máxima consideración el interés por el grupo es fácil que, además de limitar el estrés laboral, influya significativamente en el eje trabajo/familia, en la igualdad de género, en la retención del personal clave o en la reducción del absentismo laboral que son algunos beneficios potenciales asociados al teletrabajo. En conclusión, la autogestión eficiente cuando se une con un hábitat de conductas morales que tiene en cuenta los intereses de grupo y la responsabilidad social ajusta al líder ético con las ventajas de un entorno virtual de trabajo.
Open-AI model Efficient Memory Reduce Management for the Large Language Models (LLMs) Serving with Paged Attention of sharing the KV Cashes
Authors: Kumar Dr. K. Naveen
Published: August 2024

Abstract: High throughput serving of large language models (LLMs) requires batching sufficiently many requests at a time. However, existing systems struggle because the key-value cache (KV cache) memory for each request is huge and grows and shrinks dynamically. When managed inefficiently, this memory can be significantly wasted by fragmentation and redundant duplication, limiting the batch size. To address this problem we proposed a Paged Attention. An alternative algorithm inspired by the classical virtual memory and paging techniques in operating systems. An LLM serving system that achieves (1) near-zero waste in KV cache memory and (2) flexible sharing of KV cache within and across requests to further reduce memory usage. Our evaluations show that LLM improves the throughput of popular LLMs by 2-4× with the same level of latency compared to the state-of-the-art systems, such as Faster Transformer and Orca. The improvement is more pronounced with longer sequences, larger models, and more complex decoding algorithms
Balancing Agility and Control: A Comparative Analysis of Change Management in ServiceNow and BMC Helix
Authors: Yadav Sunil Kumar
Published: August 2024

Abstract: This research paper presents a comprehensive comparison of the Change Management applications offered by ServiceNow and BMC Helix. The study examines key features, risk assessment capabilities, approval workflows, integration with other ITSM processes, and reporting tools of both solutions. By evaluating their strengths and weaknesses in managing IT changes, this paper aims to provide insights for organizations seeking to optimize their change management processes in increasingly dynamic IT environments.
Seismic Performance of Multistory Reinforced Concrete Buildings by Pushover Analysis
Authors: Parashar Ram
Published: August 2024

Abstract: In this investigation the analysis of G+4, G+11 and G+21 building is situated in New Delhi (Zone IV. The seismic analysis of of G+4, G+11 and G+21 building as per IS 1893-2002. In this research pushover analysis was performed in SAP 2000 and after that is designed as per IS 456-2000 for different loads. This analysis gives better understanding seismic performance of building & also shows damage or failure of buildings. The building performance level is determined by pushover curve & demand curve. The result shows that the failure is noticed in the column of ground storey of the building. After that enlarged amount of reinforcement in the ground story the buildings have reached life safety performance level.
Parental strategies for handling sibling conflict and sibling relationships: Parent–child relationships as a mediator
Authors: Yue Yuge , Lu Kaiwu , Ye Danping
Published: August 2024

This study examined the mediating effect of parent–child relationships in the link between parental strategies for handling sibling conflict and sibling relationships. We conducted a survey of the parents of 1,368 children who had siblings and were enrolled in kindergarten, using
the Child-Centered Scale, the Control Scale, the Nonintervention Scale, the Sibling Relationship Scale, and the Parent–Child Relationship Scale. The results showed that control, childcentered, and nonintervention strategies for handling sibling conflict each predicted sibling relationships,
and parent–child relationships partially mediated the impact that the strategies had on sibling relationships. Implications for theory and practice are discussed.
Interpersonal trust, institutional trust, and inheritors' willingness to collaborate in protecting intangible cultural heritage
Authors: Xia Hongmei , Hou Guanghui
Published: August 2024

Social trust plays a pivotal role in fostering a willingness to collaborate among multiple subjects for the sustainable development of intangible cultural heritage. This study examined the effect of interpersonal trust and institutional trust on the collaboration intention of inheritors
regarding the protection of intangible cultural heritage. We conducted a survey with 220 Regong Thangka inheritors in China, employing a binary logistic model for data analysis. The findings showed that both interpersonal trust (e. g., trust in relatives, neighbors, and Tibetan Buddhists)
and institutional trust (e. g., trust in local officials and the government) positively predicted the collaboration intention of inheritors. Furthermore, there was a significant and positive correlation between the education level and the collaboration intention of inheritors. The findings
of this study contribute to a deeper understanding of the factors influencing inheritors' motivations in the collaborative efforts to protect intangible cultural heritage.
Preventive and Therapeutic values of Leech Therapy: A Review
Authors: Mir Rayees Ahmad , Nayab Mohd , Mir Uzair Yousf , Ansari Abdul Nasir
Published: August 2024

There are three therapeutic modalities in the Unani medical system: Ilaj bit Tadbeer (Regimenal Therapy), Ilaj bid Dawa (pharmacotherapy), and Ilaj bil Yad (surgery). Ilaj bit Tadbeer includes several regimenal therapies such as Hijāma (Cupping Therapy), Ta'līq or Irsal-e-'Alaq (Leech Therapy), Fasd (Venesection), Dalk (Massage), Nutūl (Therapeutic Irrigation), Qai (Emesis), Idrār-i-Bawl (Diuresis), Tariq (Diaphoresis), Mundij wa Mu'shil therapy (Concoction and purgation), Bukhoor (Medicated Steam), Kaiyy (Cauterization), Huqna (Enema) etc. Since ancient times, these therapies have been widely used for their preventive, therapeutic, and rehabilitative effects. One of the most significant regimenal therapies, Irsal-e-Alaq (Leech therapy), is still in use. Renowned Unani physicians Razi, Majoosi, Zahrawi, and Ibne Sina have discussed and recommended the use of non-poisonous (or medicinal) leeches in the prevention and treatment of a variety of illnesses, including joint disorders, chronic non-healing ulcers, and numerous skin disorders like eczema, psoriasis etc. This review paper aims to explore the preventive and therapeutic role of leech therapy.
Keywords: Unani Medical System, Therapeutic Role, Leech Therapy
A Review of Antiulcer Activity of Some Medicinal Plants
Authors: Deshpande Mangirish , Dighe Pearl , Nagare Sujit
Published: August 2024

Peptic ulcer is a gastrointestinal disorder and with increased prevalence. Peptic ulcer is breaking of endothelial lining of stomach and exposing underlying tissues. Peptic ulcer occurs due to high secretion of acid and reduced defensive factors in stomach and duodenum. It is imbalance between aggressive and defensive factors. Non-steroidal anti-inflammatory drugs and Helicobacter pylori infection also increases the risk of peptic ulcer. Indiscriminate use of synthetic drugs leads to adverse effects and concomitant use of antibiotics potentiates drug-drug interaction thus search of drugs from natural sources especially herbs is need of hour. several herbal medicines have been evaluated for its antiulcer efficacy using several ulcer inducing models in laboratory animals. Present study aims at review of gastroprotective and ulcer healing potential medicinal herbs and compilation of data. This article is only restricted to antiulcer efficacy of the medicinal plants. This review presents information about the anti-ulcer efficacy of medicinal plants and various antiulcer models used to screen them.
Keywords: Peptic ulcer, Gastric ulcer, Gastroprotective activity, Phyllanthus urinaria, Adiantum lunulatum, Ulcer healing activity
To Evaluate and Compare the Analgesic Activity of Piperine and Extracts of Piper Nigrum L. Fruit
Authors: Jain Monika , Nema Prakhar , Jain Sakshi , Khan Rubeena , Dixena Shweta , Jain Prateek Kumar , Jain Harshita
Published: August 2024

Narcotics (e.g., opioids) or non-narcotics (e.g., salicylates and corticosteroids) are used in the management of pain and inflammation, both of which have side effects, thereby emphasizing the search for natural substances. Piperine found naturally in plants of the Piperaceae family has shown inhibitory activity against 5-lipoxygenase and cycloxygenase-1 in in vitro studies. The present study was aimed to evaluate and compare the analgesic activity of pure compound, piperine along with hexane and ethanol extracts of Piper nigrum L. fruit in mice. The analgesic activity was determined by hot plate, tail immersion method and acetic acid induced writhing test in mice. The piperine showed great pain-relieving impact at a portion of 5 and 10 mg/kg when contrasted with control and standard. Greatest pain-relieving impact was noted at a portion of 10 mg/kg after 120 min. The hexane and ethanol remove demonstrated helpless pain-relieving impact at all dosages (5, 10 and 20 mg/kg) by hot plate method. However, with tail immersion method, piperine at a dose of 5mg/kg and ethanol extract at a dose of 20mg/kg after 120 min and hexane extract at a dose of 10mg/kg after 60min exhibited significant analgesic activity. In writhing test ethanol extract significantly stopped the number of writhes at dose of 20mg/kg while piperine at dose of 20mg/kg completely terminated the writhes in mice. It is concluded from the present study that Piper nigrum L. possesses potent analgesic activity in mice.
Keywords: Piper nigrum, Piperaceae, Piperine, Hot plate, Tail immersion method, Acetic acid induced writhing test
Artificial Intelligence-Assisted Fabrication of 3D Printed Technology in Pharmaceutical Development and Its Application
Authors: Meshram Shruti I. , Hatwar Pooja Ramdas , Bakal Ravindra L. , Raut Pooja V.
Published: August 2024

The concept of personalized medicine tailored to individual patients has garnered considerable attention recently, particularly in exploring the potential of 3D printing technology within the pharmaceutical and healthcare industries. 3D printing involves the layer-by-layer creation of three-dimensional objects from digital designs. This review aim to provide an in-depth discussion focusing on 3D printing technology, its role in drug delivery systems, and its application in the pharmaceutical product development process. Commonly categorized by material layering methods, 3D printers typically fall into inkjet, extrusion, or laser-based systems. The review delves into these different types of 3D printers and their diverse applications in drug delivery across various sectors. Additionally, it encompasses a selection of recent research conducted in the pharmaceutical realm concerning 3D printing for drug delivery applications and challenges.
Keywords: 3D printed formulation, Laser based printing, inkjet printing, extrusion-based printing
Preliminary Study of pH, EC, TDS, and Heavy Metals Analysis of Oxbow’s Sediments in Bandung Region
Authors: Alfitrah Siti Percika , Kirana Kartika Hajar , Fitriansyah Rd Agung , Shafaria Mileani
Published: August 2024

The Oxbow Lake is a vital part of river and it usually used for household, agricultural, and fisheries needs. The oxbow lake faces pollution risks from human activities. This study aims to assess the quality of water and sediment by pH, EC, and TDS of water and sediment as well as heavy metal content in sediment. The results show that the environmental conditions of the oxbow lakes around the Upper Citarum River are generally good because they fall within the safe limits for hygiene and sanitation standards, except for Babakan Patrol Oxbow Lake and Sapan Oxbow Lake. Unfortunately, the heavy metal levels in samples O1-2, O4-2, and O7-1 exceed sediment quality guidelines. These measurements indicate evidence of anthropogenic influence on sediment samples.
Implementasi Video Based Laboratory Menggunakan Software Tracker dalam Menentukan Percepatan Gravitasi Bumi di Berbagai Kota di Pulau Sulawesi Indonesia dan Turki
Authors: Zahran Muhammad , Medellu Natania Carmenita , Sari Ika Mustika , Rizqi Muhammad , Selamat Muhammad Banda
Published: August 2024

FREE FALL EXPERIMENTS HAVE BEEN CONDUCTED IN VARIOUS CITIES IN SULAWESI AND ONE CITY IN TURKEY WITH THE AIM OF DETERMINING THE ACCELERATION OF GRAVITY.THE ACCELERATION OF GRAVITY IS DETERMINED BY IMPLEMENTING A VIDEO-BASED LABORATORY.THE DATA OBTAINED ARE FREE FALL MOTION VIDEO DATA ANALYZED BY USING TRACKER SOFTWARE.FROM THE ANALYSIS CONDUCTED, THE PRICES OF THE EARTH'S GRAVITY ACCELERATION ARE SUCCESSFUL IN THE CITIES OF JENEPONTO, MAKASSAR, MINAHASA, AND ISTANBUL OF: : 9.793 , 9.778 9.72 , AND 9.76 .USING ROOT MEAN SQUARE DEVIATION (RMSD) BASED ON APPLICATIONS EARNED SUCCESSFULLY: (JENEPONTO), (MAKASSAR), (MINAHASA) AND (ISTANBUL).ERROR OF MEASUREMENT RESULTS ARE ON THE ORDER SO THAT THE AUTHORIZATION CAN BE ACCEPTED.THE ACCELERATION OF GRAVITY THAT WAS OBTAINED WAS APPROACHING THE LITERATURE VALUE, ie, .THEREFORE, IMPLEMENTATION OF THE VIDEO-BASED LABORATORY (VBL) ANALYSIS METHOD USING THE SOFTWARE TRACKER TO DETERMINE THE ACCELERATION OF GRAVITY IN VARIOUS HEARTS OF THE EARTH, WAS EFFICIENTLY AND EFFECTIVELY DONE.
DEVELOPMENT OF INTERACTIVE PHYSICS LEARNING VIDEOS BASED ON SCIENCE ENVIRONMENT TECHNOLOGY SOCIETY AT THE HIGH SCHOOL LEVEL
Authors: Julia Cut Rahma , Jannah Misbahul , Rusydi Rusydi , Hamid Abdul
Published: August 2024

This research is motivated by the use of learning methods that are still monotonous and uninteresting, the discussion of one of the physics materials that is difficult for students to understand, namely static fluid materials. This results in students having difficulty understanding the concepts and equations contained in static fluid materials. To overcome this problem, an interactive physics learning video based on the Science Environment Technology Society (SETS) was developed in order to provide students with an understanding of static fluid materials and become a digital media that can be used in the long term because it is flexible so that it can be used anywhere to repeat static fluid materials. The objectives of this research are: (1) To design interactive physics learning videos based on SETS at the high school/MA level; (2) To find out the feasibility of interactive physics learning videos based on SETS at the high school/MA level and (3) To find out the practicality of interactive physics learning videos based on SETS at the high school/MA level. This study uses the Research and Development (R&D) method based on the Alessi and Trollip development model. In this study, a product was produced in the form of interactive physics learning videos based on SETS. The results of the study show that SETS-based interactive physics learning videos have met the category of very feasible. This is determined based on the results of validation from media experts with a percentage of 90.4% included in the "very feasible" criteria and the validation results from material experts obtained a percentage of 91.2% with the "very feasible" criteria and user validation results with a percentage of 93.2% with the "very feasible" criteria. The results of the practicality assessment by students received a percentage of 95% with the category "very practical" used in the learning process. Thus, it can be concluded that SETS-based learning videos can be used in the learning process.
Związki romantyczne osób z nadpobudliwością psychoruchową
Authors: Kubiak Hanna
Published: August 2024

Tekst dotyczy problematyki związków romantycznych osób z nadpobudliwością psychoruchową. Osoby o takiej charakterystyce są narażone na ryzyko współwystępowania licznych problemów, m.in. występowania zaburzeń towarzyszących, łamania prawa, przedwczesnego wchodzenia w związki intymne, niekorzystnego przebiegu ścieżki edukacyjnej i zawodowej, uzależnienia. W artykule poddano analizie różne aspekty relacji romantycznych osób z ADHD, m.in. wchodzenie w relacje, ich trwałość oraz jakość, w tym odmienność w zakresie kształtu intymności i życia seksualnego w porównaniu do populacji ogólnej. Wiedza na temat specyfiki wymienionych aspektów relacji może stanowić podstawę ukierunkowanego wspierania osób z ADHD i ich partnerów. To wsparcie jest potrzebne jako element profilaktyki wyżej wskazanych problemów związanych z występowaniem ADHD.
Seksualne drapieżniczki Analiza czynników ryzyka i czynników chroniących w kontekście podejmowanych oddziaływań korekcyjnych
Authors: Kowalczyk Małgorzata H.
Published: August 2024

Celem artykułu jest wskazanie spektrum czynników ryzyka zarówno o charakterze statycznym, jak i dynamicznym oraz wskazanie antagonistycznych wobec nich czynników chroniących. Poznanie zakresu czynników sprzyjających wchodzeniu na drogę przestępczych zachowań seksualnych przez kobiety ma duże znacznie terapeutyczno-koerekcyjne. Pozwala bowiem opracować formy oddziaływań adresowanych do tej kategorii sprawczyń oraz ocenić ryzyko powrotności do zachowań przestępczych. Wykorzystaną metodą jest analiza źródeł wtórnych. Opracowanie podzielono na trzy części. W pierwszej dokonano charakterystyki i interpretacji pojęć powiązanych z seksualnym wykorzystywaniem dzieci. W drugiej scharakteryzowano sprawczynie wykorzystywania seksualnego dzieci. W ostatniej części zostały opisane czynniki ryzyka powiązane z dokonywaniem kontaktowych przestępstw seksualnych przez kobiety. Uwzględniono zarówno tak zwane czynniki statyczne, jak i dynamiczne (DRF). Dodatkowym elementem przydatnym w opracowaniu oddziaływań korekcyjnych jest ustalenie czynników chroniących (PF), które nie tylko redukują ryzyko powrotności do przestępstwa, ale także mogą wskazywać pożądany kierunek zmian korekcyjnych.
Wzmacnianie zasobów odpornościowych w ramach procesu usamodzielnienia wychowanków placówek opiekuńczo-wychowawczych jako forma profilaktyki niedostosowania społecznego i marginalizacji
Authors: Skowrońska-Pućka Agnieszka
Published: August 2024

Celem artykułu jest ukazanie możliwości praktycznego zastosowania znanych, potwierdzonych empirycznie teorii i modeli kształtowania zasobów odpornościowych w trakcie realizacji procesu usamodzielnienia, jako elementu prewencji niedostosowania społecznego wychowanków placówek opiekuńczo-wychowawczych. W artykule scharakteryzowano specyfikę procesu usamodzielnienia realizowanego w ramach instytucjonalnej pieczy zastępczej, zaakcentowano profilaktyczny potencjał procesu usamodzielnienia, zaprezentowano inspiracje teoretyczne mogące wpłynąć na jego efektywność i skuteczność w zakresie przeciwdziałania zagrożeniu niedostosowaniem i marginalizacją społeczną. Zaprezentowana refleksja jest wynikiem doświadczeń zawodowych, studiów teoretycznych autorki oraz prowadzonych w rzeczywistości instytucjonalnej pieczy zastępczej weryfikacji empirycznych. Wskazane idee mogą być propozycjami do podjęcia istotnych działań naprawczych w charakteryzowanym obszarze, są też niezwykle ważne z uwagi na swoją praktyczno-profilaktyczną rolę w zakresie przeciwdziałania zagrożeniu niedostosowaniem wychowanków opuszczających placówki opiekuńczo-wychowawcze.
Generowanie pozytywnych emocji w doświadczeniach stresowych
Authors: Cywińska Małgorzata
Published: August 2024

Wielowymiarowość społeczno-kulturowej rzeczywistości często rodzi wiele trudnych, stresowych sytuacji, tak w życiu dorosłych, jak i dzieci. Kojarzone są one głównie z negatywnymi emocjami i dystresem. Tymczasem Susan Folkman i Judith Moskowitz podkreślają rangę występowania w transakcjach stresowych emocji pozytywnych, ich adaptacyjnej roli w procesie stresu, eksponując, iż podłożem pozytywnych emocji w stresowych sytuacjach może być poszukiwanie i odnajdowanie pozytywnego znaczenia doświadczanych sytuacji. Autorki wprowadziły do klasycznego modelu stresu Richarda S. Lazarusa i Susan Folman trzecią funkcję radzenia sobie (obok radzenia sobie skoncentrowanego na problemie i skoncentrowanego na emocjach) – skoncentrowane na znaczeniu. Charakterystyka teoretyczna powyżej wskazanych aspektów sytuacji stresowych stała się przedmiotem analiz niniejszego artykułu. Została ona wsparta „ilustracją” wycinka badań empirycznych dotyczących sytuacji stresowych dzieci w młodszym wieku szkolnym i ich strategii radzenia sobie z nimi, służących wzbudzaniu emocji pozytywnych w tego rodzaju transakcjach. Badania empiryczne objęły dwieście osiemdziesięcioro dzieci z trzecich klas szkoły podstawowej i odnosiły się do metody sondażu diagnostycznego oraz techniki wywiadu i ankiety. Poszukiwanie i odnajdowanie pozytywnego znaczenia zdarzeń stresowych oraz występujących w nich emocji pozytywnych jest nie tylko istotne w adaptacyjnym radzeniu sobie ze stresorami, rozwijaniu odporności psychicznej jednostki, ale także w niwelowaniu zaburzeń socjalizacyjnych.
Stygmatyzacja społeczna jako perspektywa teoretyczno-empiryczna na podstawie analizy przypadku byłej skazanej
Authors: Żeromska-Charlińska Joanna
Published: August 2024

W artykule podjęto próbę przedstawienia perspektywy stygmatyzacji jako kategorii teoretycznej oraz analitycznej związanej z sytuacją kobiety, byłej skazanej. Koncepcja stygmatyzacji, stanowiąca jedną z głównych kategorii analitycznych wydobytych w toku badań własnych, posłużyła autorce jako egzemplifikacja, symptomatologia biograficznego uczenia się, zachodzącego w doświadczeniach dorosłej kobiety poddanej dryfowi rzeczywistości postpenitencjarnej – wstydu, upokorzenia, piętna. Narracja badanej zakreśla ramy obciążenia ryzykiem zewnętrznym, ale i wewnętrznym, jak też ryzyka, podejmowanego w ramach przekraczania siebie. Dokonano próby rozumienia aktualnej sytuacji badanej w inkluzyjnej walce, a nie oceny jej postępowania, lokując dociekania badawcze w paradygmacie konstruktywistycznym i interpretacyjnym. Głównym celem uczyniono próbę rekonstrukcji oraz opisu sposobu zarządzania sobą oraz negocjowania tożsamości w interakcjach społecznych kobiety dzieciobójczyni po odbyciu wyroku. W badaniach wykorzystano interpretacyjną analizę hermeneutyczno-fenomenologiczną, koncentrującą się na zrozumieniu doświadczeń badanej oraz opisie postrzegania samej siebie. Zdobyta wiedza wskazuje swoistą perspektywę badań nieczęsto obecnych w dyskursie naukowym. Analiza materiału empirycznego wykazała, iż możliwości dekonstruowania i przezwyciężania separacji przez badaną aktualnie blokują szansę na socjalizację z powodu nieprzepracowania kryzysu stygmatyzacji społecznej i doświadczeń.
Rodzinne uwarunkowania zachowań ryzykownych wychowanków placówek opiekuńczo-wychowawczych
Authors: Skowrońska-Pućka Agnieszka
Published: August 2024

Artykuł ma charakter teoretyczno-badawczy i jego celem jest ukazanie powiązań między kondycją rodziny a podejmowaniem przez dzieci i młodzież zachowań problemowych (koncepcja Jessorów). Celem podjętych rozważań jest dokonanie, na podstawie wyników badań, charakterystyki czynników ryzyka występujących w rodzinach pochodzenia wychowanków placówek opiekuńczo-wychowawczych sprzyjających podejmowaniu zachowań ryzykownych. Charakterystyka rodzinnych uwarunkowań zachowań ryzykownych wynika zarówno z wniosków płynących z autorskich badań realizowanych w duchu jakościowym, z wykorzystaniem metody biograficznej, jak i metaanalizy innych dostępnych na ten temat doniesień badawczych. Dokonana charakterystyka może ułatwiać diagnozę i rozumienie etiologii zachowań ryzykownych dzieci i młodzieży z grup defaworyzowanych oraz sprzyjać projektowaniu działań profilaktyczno-wychowawczych realizowanych w ramach pobytu w placówce, adresowanych i adekwatnych do potrzeb tej grupy odbiorców – wychowanków placówek opiekuńczo-wychowawczych.
O discurso do preconceito disfarçado contra o público LGBT+ na esfera política: representações e ethos (Discourse of disguised prejudice against LGBT+ people in the political sphere: representations and ethos)
Authors: Freitas Ernani Cesar de , Lago Kaian , Boaventura Luis Henrique
Published: August 2024

Este artigo tem por objetivo identificar o processo de representação do ethos presente no discurso político de preconceito disfarçado dirigido ao público LGBT+. São utilizadas as contribuições de Goffman (2018) sobre representação e seus fenômenos; e de Maingueneau (2019) sobre as cenas enunciativas e o ethos discursivo, além de referenciais complementares. A pesquisa é exploratória, bibliográfica e documental, com análise qualitativa de um corpus constituído por um recorte do discurso do deputado Márcio Gualberto em debate na Assembleia Legislativa do RJ sobre a concessão do Prêmio Cidadania, Direito e Respeito à Diversidade para o grupo Arco-Íris, que defende os direitos LGBT+s no estado. Como resultado, apresentamos que a criação de um discurso de preconceito disfarçado apenas mascara um real posicionamento do enunciador sobre o tema, sendo construído com base em uma representação falsa de suas reais intenções e em um ethos que reafirma os estereótipos já instalados na memória coletiva.
Estratégias anafóricas em redações escolares: uma proposta de ensino por meio de sequência didática (Anaphoric strategies in essays: a teaching proposal through a didactic sequence)
Authors: Araujo Alex Marcelo da Silva , Oliveira Jairo Venício Carvalhais
Published: August 2024

Este trabalho apresenta os resultados de uma experiência didática com estratégias de referenciação textual no processo de produção de redações escolares no modelo Enem. Para isso, foi feito um estudo em caráter quali-quantitativo, de natureza aplicada, adotando-se o modelo de sequência didática. A pesquisa foi realizada em uma turma de 1º ano do Ensino Médio brasileiro e possibilitou a análise comparativa de textos produzidos em fase inicial e em fase final da intervenção proposta. Os resultados apontam uma evolução significativa no uso de processos anafóricos na produção escrita dos estudantes, evidenciando o papel coesivo da referenciação textual na construção da coerência e na projeção discursivo-argumentativa dos textos. Dessa forma, nota-se que os mecanismos anafóricos de retomada e de recategorização de objetos de discurso no plano textual, trabalhados de forma modularizada, contribuem para o uso reflexivo da língua e atuam como recursos de primeira importância na construção de sentidos.
A clínica fonoaudiológica como espaço de (co)construção de narrativas de vida de pessoas com afasia (The speech therapy clinic as a space for (co)construction of life narratives for people with aphasia)
Authors: Santana Ana Paula , Guarinello Ana Cristina , Donida Lais Oliva
Published: August 2024

A clínica fonoaudiológica para pessoas com afasia pode ser um espaço de reelaboração de narrativas de vida. O narrar evidencia a relação de reciprocidade entre memória e língua(gem), o que implica trabalho linguístico e subjetivo. O objetivo deste artigo é analisar a produção de narrativas de vida de pessoas com afasia no contexto da clínica fonoaudiológica. Para tanto, será apresentado um estudo qualitativo de uma produção bibliográfica de uma pessoa afásica participante de um grupo, tendo como perspectiva de análise os estudos bakhtinianos. Os resultados apontam para a importância da autoria - que já estava na fala, mas que não era, muitas vezes, reconhecida. Com isso, se pode dizer que a clínica fonoaudiológica, ao se inscrever em uma perspectiva discursiva de língua(gem), permite que o trabalho sobre e com a língua(gem) possibilite a construção de práticas narrativas que afirmam o lugar do sujeito com afasia como narrador da própria história.