bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of two different approaches for sensitivity analysis in Heihe River basin (China)
Authors: Huo Aidi , Huang Zhikai , Cheng Yuxiang , Van Liew Michael W.
Published: November 2019

Distributed watershed models should pass through a careful sensitivity analysis and calibration procedure before they are utilized as a decision making aid in the planning and management of water resources. Although manual approaches are still frequently used for sensitivity and calibration, they are tedious, time consuming, and require experienced personnel. This paper describes two typical and effective automatic approaches for sensitivity analysis and calibration for the Soil and Water Assessment Tool (SWAT). These included the Sequential Uncertainty Fitting (SUFI-2) algorithm and Shuffled Complex Evolution (SCE-UA) algorithm. The results show the following. (1) The main factor that influences the simulated accuracy of the Heihe River basin runoff is the Soil Conservation Service (SCS) runoff curve parameters. (2) SWAT performed very well in the Heihe River basin. According to the observed runoff data from 2005 to 2013, the determination coefficient R2 of the simulation and the efficiency coefficient (Ens) of the model was higher than 0.8. (3) Compared with the Shuffled Complex Evolution, the SUFI-2 algorithm provides almost the same overall ranking of the sensitive parameters, but it is found to require less time with higher accuracy. The SUFI-2 provides a practical and flexible tool to attain reliable deterministic simulation and uncertainty analysis of SWAT, it can lead to a better understanding and to better estimated values and thus reduced uncertainty.
An Effective Cumulative Torsion Angles Model for Prediction of Protein Folding Rates
Authors: Li Yanru , Zhang Ying , Lv Jun
Published: November 2019

Background:

Protein folding rate is mainly determined by the size of the
conformational space to search, which in turn is dictated by factors such as size, structure and
amino-acid sequence in a protein. It is important to integrate these factors effectively to form a
more precisely description of conformation space. But there is no general paradigm to answer this
question except some intuitions and empirical rules. Therefore, at the present stage, predictions of
the folding rate can be improved through finding new factors, and some insights are given to the
above question.

Objective:

Its purpose is to propose a new parameter that can describe the size of the
conformational space to improve the prediction accuracy of protein folding rate.

Method:

Based on the optimal set of amino acids in a protein, an effective cumulative backbone
torsion angles (CBTAeff) was proposed to describe the size of the conformational space. Linear
regression model was used to predict protein folding rate with CBTAeff as a parameter. The degree
of correlation was described by the coefficient of determination and the mean absolute error MAE
between the predicted folding rates and experimental observations.

Results:

It achieved a high correlation (with the coefficient of determination of 0.70 and MAE of
1.88) between the logarithm of folding rates and the (CBTAeff)0.5 with experimental over 112 twoand
multi-state folding proteins.

Conclusion:

The remarkable performance of our simplistic model demonstrates that CBTA based
on optimal set was the major determinants of the conformation space of natural proteins.
Early-life Programming of Type 2 Diabetes Mellitus: Understanding the Association between Epigenetics/Genetics and Environmental Factors
Authors: Kadayifci Fatma Z. , Haggard Sage , Jeon Sookyoung , Ranard Katie , Tao Dandan , Pan Yuan- Xiang
Published: November 2019

Type 2 Diabetes Mellitus is an increasing public health problem that poses a severe social
and economic burden affecting both developed and developing countries. Defects in insulin signaling
itself are among the earliest indications that an individual is predisposed to the development of insulin
resistance and subsequently Type 2 Diabetes Mellitus. To date, however, the underlying molecular
mechanisms which result in resistance to the actions of insulin are poorly understood. Furthermore, it
has been shown that maternal obesity is associated with an increased risk of obesity and insulin resistance
in the offspring. However, the genetic and/or epigenetic modifications within insulin-sensitive
tissues such as the liver and skeletal muscle, which contribute to the insulin-resistant phenotype, still
remain unknown. More importantly, a lack of in-depth understanding of how the early life environment
can have long-lasting effects on health and increased risk of Type 2 Diabetes Mellitus in adulthood
poses a major limitation to such efforts. The focus of the current review is thus to discuss recent
experimental and human evidence of an epigenetic component associated with components of nutritional
programming of Type 2 Diabetes Mellitus, including altered feeding behavior, adipose tissue,
and pancreatic beta-cell dysfunction, and transgenerational risk transmission.
Bioactive Flavonoids from Verbenaceae
Authors: Wang Kui-Wu , Zhang Ting-Ting
Published: November 2019

Flavonoids are widely distributed in the plant kingdom and possess a variety of biological
activities, such as anti-oxidant, anti-inflammatory, and anti-viral activities. Due to the structural diversity
and biological activity, flavonoid derivatives isolated from Verbenaceae family have received
a lot of attention by the research scholars. In this paper, a total of 150 natural flavonoids isolated
from Verbenaceae and their bioactivities were summarized.
Prevalence and Risk Factors of Disordered Eating Attitudes and Behaviors Among High-school Girls in Al-Madinah City, Saudi Arabia
Authors: Al-Qahtani Awad M. , Al-Harbi Lamees M.
Published: November 2019

Objectives::

To determine the prevalence of disordered eating attitudes and behaviors
among high-school girls in Al-Madinah City, Saudi Arabia.

Methods::

A cross-sectional descriptive study was conducted in Al-Madinah city in 2014-15. A multi-
stage random sampling technique was adopted to include female students of government secondary
schools. The Eating Attitudes Test (EAT-26) and socio-economical questionnaires were used in the
study for assessing the prevalence of disordered eating. All data were entered and analyzed using
SPSS version 20.

Results::

Overweight and obesity were reported among 11.2% and 5.6% of them, respectively,
whereas 31.3% of the participants were underweight. The overall prevalence of disordered eating
attitudes among female students was 42.5%. This rate was significantly higher among younger
(≤16 years old) and those of the first scholastic level than others. The rate of disordered eating
attitude was reported at a higher rate among obese students (59.1%) than underweight (41.5%) and
normal students (42.4%). The commonest reported disordered eating behavior was self-reported
binge eating behaviour (25.2%), followed by self-induced vomiting (8.7%) and the use of laxatives/
diuretics to control weight (6.1%).

Conclusion::

The findings show a high prevalence of disordered eating attitude among high school
female students in Al-Madinah city. Younger girls and those of the first scholastic level showed
higher disordered eating attitude.
Determination of Phenolic Compounds’ Extraction Conditions from Pistacia palaestina Leaves at Two Different Stages of Maturity
Authors: Zam Wissam , Ali Ali , Hasan Razan
Published: November 2019

Background:

Phenolic compounds are distributed throughout the plant kingdom. Numerous investigations have proved that Pistacia species have secondary metabolites, and these contain different classes of bioactive phenolic compounds.

Objective:

The objective of the present work was to optimize the extraction conditions of phenolic compounds from Pistacia palaestina leaves cultivated in Syria and find out the effects of the solvent type, extraction time, and temperature on total phenolic content (TPC) and in vitro antioxidant activity% (AA%). Two different growth stages were studied.

Methods:

Antioxidant activity and total phenolic content values were estimated using 2,2’-diphenyl- 1-picrylhydrazyl and Folin-Ciocalteu methods, respectively.

Results:

The highest TPC and AA% were found in fresh leaves (14.32g/100g and 92.69%, respectively). The optimum extraction solvent for phenolic recovery and antioxidant capacity was acetone 40%. Changes both in temperature (25, 40, 60 and 80°C) and time (15, 30, 45 and 60 min) had no significant influence on TPC and AA% of Pistacia extracts.

Conclusion:

Phenolic compounds could be extracted in a short time at a low temperature and could be used as natural antioxidant agents.
Molecular Complex of Glycyrrhizic Acid Monoammonium Salt with Cholesterol
Authors: Yakovishin Leonid A.
Published: November 2019

Background:

Glycyrrhizic Acid (GA) is the major triterpene saponin of licorice roots. The
most important derivative of GA is its monoammonium salt (glycyram, GC). Some pharmacological
properties of triterpene saponins explain their molecular complexation with Cholesterol (Chol). However,
the molecular complexation of GC with Chol has not been proven. The functional groups of GA
and GC involved in the interactions with Chol were not identified.

Methods:

The complexation has been investigated by the method of isomolar series in the spectrophotometric
version, IR, and 13C NMR spectroscopy. The constant is calculated on the basis of isomolar
curves.

Results:

The molecular complex of GC with Chol has been prepared for the first time. It has been
shown that GC forms a 1 : 1 complex with Chol having a stability constant Ks of (3.3 ± 0.2)×105
(mol/L)-1 (in 70% aqueous EtOH at 18 °С).

Conclusion:

Intermolecular interaction in the complex is carried out by hydrogen bond formation between
C=O group of GC (in carboxyl group of the terminal residue of glucuronic acid in the carbohydrate
part) and 3β-hydroxyl group of Chol: -С=О⋅⋅⋅Н-О-. Hydrophobic contacts of the aglycone part of
GC with a lipophilic Chol molecule are possible.
Genetics of Atrial Fibrilation: In Search of Novel Therapeutic Targets
Authors: Lozano-Velasco Estefanía , Garcia-Padilla Carlos , Aránega Amelia E. , Franco Diego
Published: November 2019

:

Atrial fibrillation (AF) is the most frequent arrhythmogenic disease in humans, ranging from 2% in the general population and rising up to 10-12% in 80+ years. Genetic analyses of AF familiar cases have identified a series of point mutations in distinct ion channels, supporting a causative link. However, these genetic defects only explain a minority of AF patients. Genomewide association studies identified single nucleotide polymorphisms (SNPs), close to PITX2 on 4q25 chromosome, that are highly associated to AF. Subsequent GWAS studies have identified several new loci, involving additional transcription and growth factors. Furthermore, these risk 4q25 SNPs serve as surrogate biomarkers to identify AF recurrence in distinct surgical and pharmacological interventions. Experimental studies have demonstrated an intricate signalling pathway supporting a key role of the homeobox transcription factor PITX2 as a transcriptional regulator. Furthermore, cardiovascular risk factors such as hyperthyroidism, hypertension and redox homeostasis have been identified to modulate PITX2 driven gene regulatory networks. We provide herein a state-of-the-art review of the genetic bases of atrial fibrillation, our current understanding of the genetic regulatory networks involved in AF and its plausible usage for searching novel therapeutic targets.
Analysis of Senegal Type Vertical Axis Wind Turbines Arrangement in Wind Farm
Authors: Zheng Li , Wenda Zhang , Ruihua Han , Weiqiang Qi
Published: November 2019

Background:

In a wind farm, the wind speed of the downstream wind turbine will be
lower than the wind speed of the upstream wind turbine due to the influence of the wake. Therefore,
the wake of wind turbines is one of the uncertain factors predicting the annual power generation of
the wind farms. The study on the wake can effectively improve the efficiency of power generation.
The arrangement of vertical axis wind turbines in wind farms is rarely studied. Therefore, it is important
to study the vertical layout of wind turbines under the influence of wakes to obtain the best
layout and unit spacing.

Objective:

The objective of this study is to obtain the optimal layout and unit distance of wind turbines
in Senegal wind farms by studying the arrangement of Senegal vertical axis wind turbines in
wind farms.

Methods:

Based on the ANSYS CFX flow field calculation module, the fluid dynamics model of
the Senegal fan was established and the flow field simulation analysis was carried out. Based on the
Jensen wake model and its improved model, three layout methods for the wind farm wind turbines
were proposed: two units were arranged in series, two units were arranged in parallel, and three
units were staggered. Through the simulation model, the wind energy utilization coefficient and
wind speed of the wind turbine in the wind farm were obtained.

Results:

The optimal separation distance between the units was analyzed from four different angles:
wind energy utilization coefficient, torque analysis, downstream tail flow and wind speed cloud contour.
Finally, based on the optimal arrangement and unit distance, a triangular staggered wind farm
composed of 10 units was established, and the integrated flow field characteristics of the whole
wind farm were simulated and analyzed. The integrated flow field wake characteristics of the wind
farm were obtained.

Conclusion:

In all the three arrangements, the optimum distance between the units must be three
times the diameter of the wind turbine. This arrangement ensures that most of the units are unaffected
by the wake, the area affected by the low-velocity wake of the wind farm is small, and the area
affected by the high-speed wake is large.
Antiproliferative Effects of Ocimum basilicum Methanolic Extract and Fractions, Oleanolic Acid and 3-epi-Ursolic Acid
Authors: Qamar Kehkashan Arshad , Farooq Ahsana Dar , Siddiqui Bina S. , Kabir Nurul , Begum Sabira
Published: November 2019

Aims:

The aim of the current study was to identify active compound(s) responsible
for the antiproliferative effects of O. basilicum and explore their underlying mechanism/s.
Background: Plants have been the source of medicines for the treatment of various diseases
since ancient times. Ocimum basilicum (Sweet Basil, Bobai Tulsi) has been used in the folk
medicine for the treatment of human liver, spleen and stomach cancers.

Background:

Plants have been the source of medicines for the treatment of various diseases
since ancient times. Ocimum basilicum (Sweet Basil, Bobai Tulsi) has been used in the folk
medicine for the treatment of human liver, spleen and stomach cancers.

Objective:

To emphasize the importance of O. basilicum as a potential novel non-toxic alternative
to the conventional anticancer therapy.

Method:

O. basilicum (aerial parts) methanolic extract and fractions were screened against
HT-144, MCF-7, NCI-H460 and SF-268 human cancer cell lines using sulforhodamine B
assay. The more active Petroleum Ether Insoluble (PEI) fraction was fractionated into six
sub-fractions (OB-1 to OB-6). Four pure compounds (3-O-methyl ursolic acid, oleanolic acid,
3-epi-ursolic acid and ursolic acid) were isolated from the more potent sub-fraction OB-
6. Triple channel immunofluorescence microscopy was employed to observe the effects of
methanolic extract, PEI fraction, sub-fractions OB-5 and OB-6, 3-epi-ursolic acid and
oleanolic acid on the cytoskeleton and nuclei of MCF-7 cells.

Result:

The methanolic extract and the PEI fraction exhibited selectively greater growth inhibition
against MCF-7 cell line (TGI: 56 and 36.2 µg/ml, respectively). By using triple
channel immunofluorescence microscopy, it was observed that the methanolic extract, PEI
fraction, sub-fraction OB-5 and 3-epi-ursolic acid induced irregular mitotic spindle formation
and slowing of mitotic progression in MCF-7 cells while sub-fraction OB-6 induced
mitotic arrest in the prophase stage. F-actin aggregation was also visible in PEI fraction, subfraction
OB-5 and 3-epi-ursolic acid treated MCF-7 cells.

Conclusion:

These results emphasize the importance of O. basilicum as a potential novel
non-toxic alternative to the conventional anticancer therapy and suggest that it inhibits the
growth of MCF-7 cancer cells via multiple mechanisms such as interaction with the microtubules
and mitotic spindle apparatus, and F-actin aggregation.
Pathogenic activity of Isaria spp. for control of Dactylopius opuntiae (Hemiptera: Dactylopiideae) and the effects of selected insecticides
Authors: Da Silva Lopes Rosineide , Gonçalves De Oliveira Luciana , De Lima Geiziquele , Dos Santos Correia Maria Tereza , Da Costa Antonio Félix , De Luna-Alves Lima Elza Áurea , De Menezes Lima Vera Lúcia
Published: November 2019

We analyzed the activity of the entomopathogenic fungi Isaria farinosa, I. fumosorosea and I. javanica against the cochineal Dactylopius opuntiae, as well as the effects of the insecticides clorpirifos, acetamiprid, thiamethoxam and lambda-cyhalothrin on the conidia germination, mycelium growth and a sporulation of the fungi. These fungi were not pathogenic to cochineal. This the first report of the efficiency of Isaria spp. against this the insect. The bioassays of the compatibility of the insecticides acetamiprid and thiametoxam with species of Isaria indicate the possibility of the joint use of these products in studies on the control of D. opuntiae.
Mind the App: Considerations for the Future of Mobile Health in Canada
Authors: Zawati Ma'n H , Lang Michael
Published: November 2019

Over the past decade, smartphone technology has become increasingly sophisticated and ubiquitous. Modern smartphones, now owned by more than three quarters of Canadians and 94% of millennials, perform an array of functions that are potentially useful in the health care context, such as tracking fitness data, enabling health record sharing, and providing user-friendly platforms for disease management. Approximately half of smartphone users have downloaded at least one health app, and clinicians are increasingly using them in their practice. However, despite widespread use, there is little evidence that supports their safety and efficacy. Few apps have been independently evaluated and many lack basic patient protections such as privacy policies. In this context, the demand for the regulation of mobile health apps has increased. Against this backdrop, regulators, including Health Canada, have begun to propose regulating the use of smartphones in health care. In this viewpoint, we respond to Health Canada’s recent proposal to regulate smartphone use in Canada according to a risk-based model. We argue that although Health Canada’s recent proposed approach is promising, it may require complementary regulation and oversight.
Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study (Preprint)
Authors: Humphry Nia Angharad , Wilson Thomas , Cox Michael Christian , Carter Ben , Arkesteijn Marco , Reeves Nicola Laura , Brakenridge Scott , McCarthy Kathryn , Bunni John , Draper John , Hewitt Jonathan
Published: November 2019

BACKGROUND

Older patients account for a significant proportion of patients undergoing colorectal cancer surgery and are vulnerable to a number of preoperative risk factors that are not often present in younger patients. Further, three preoperative risk factors that are more prevalent in older adults include frailty, sarcopenia, and malnutrition. Although each of these has been studied in isolation, there is little information on the interplay between them in older surgical patients. A particular area of increasing interest is the use of urine metabolomics for the objective evaluation of dietary profiles and malnutrition.

OBJECTIVE

Herein, we describe the design, cohort, and standard operating procedures of a planned prospective study of older surgical patients undergoing colorectal cancer resection across multiple institutions in the United Kingdom. The objectives are to determine the association between clinical outcomes and frailty, nutritional status, and sarcopenia.

METHODS

The procedures will include serial frailty evaluations (Clinical Frailty Scale and Groningen Frailty Indicator), functional assessments (hand grip strength and 4-meter walk test), muscle mass evaluations via computerized tomography morphometric analysis, and the evaluation of nutritional status via the analysis of urinary dietary biomarkers. The primary feasibility outcome is the estimation of the incidence rate of postoperative complications, and the primary clinical outcome is the association between the presence of postoperative complications and frailty, sarcopenia, and nutritional status. The secondary outcome measures are the length of hospital stay, 30-day hospital readmission rate, and mortality rate at days 30 and 90.

RESULTS

Our study was approved by the National Health Service Research Ethics Committee (reference number: 19/WA/0190) via the Integrated Research Application System (project ID: 231694) prior to subject recruitment. Cardiff University is acting as the study sponsor. Our study is financially supported through an external, peer-reviewed grant from the British Geriatrics Society and internal funding resources from Cardiff University. The results will be disseminated through peer-review publications, social media, and conference proceedings.

CONCLUSIONS

As frailty, sarcopenia, and malnutrition are all areas of common derangement in the older surgical population, prospectively studying these risk factors in concert will allow for the analysis of their interplay as well as the development of predictive models for those at risk of commonly tracked surgical complications and outcomes.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/16846
An Iranian academic social network is coming (Preprint)
Authors: Dehghani Mohammad , Shahin Akhondzadeh , Bita Mesgarpour , Reza Ferdousi
Published: November 2019

UNSTRUCTURED

Iran has faced severe sanctions in recent years from some countries. Due to the dependence of the Iranian health industry on government payments, the health of the people in this country has suffered a lot. One of the solutions for Iran's sanctions to reduce the impact of sanctions on health is to rely on domestic researchers, but researchers in Iran are having problems. One way to reduce researchers' problems is to use the National Academic Social Network. This article describes the steps of setting up an academic social network in a developing country in four stages.
Can Garfield make children eat healthier?: A cluster-randomized controlled trial to examine the effect of a serious health game on children’s eating behavior. (Preprint)
Authors: Folkvord Frans , Hage Gosse , Theben Alexandra
Published: November 2019

BACKGROUND

Currently the dietary intake patterns of children do not meet the prescribed dietary guidelines. Consequently childhood obesity is one of the most serious health concerns and innovative methods need to be developed and tested in order effectively improve the dietary intake of children. Learning children how to cope with the overwhelming number of unhealthy food cues could be conducted effectively by serious health games.

OBJECTIVE

The main aim of this study was to examine the effect of a serious health computer game on young children’s eating behavior and attitudes towards healthy and unhealthy foods.

METHODS

A cluster-randomized controlled trial with a between-subject design was conducted (N=157; 8-12 years), whereby children played a game that promoted a healthy lifestyle or were in the control condition. The game was designed in collaboration with researchers and pilot-tested before conducting the experiment among a group of children repeatedly. After one week of playing, attitudes towards food snacks and actual intake was assessed, whereby children could eat at libitum from fruits or energy-dense snacks.

RESULTS

The results showed that playing a serious health game did not have an effect on the attitude towards fruits or energy-dense snacks and on the intake of fruits or less energy-dense snacks, compared to the control group. Additional Bayesian analyses supported these findings.

CONCLUSIONS

Serious health games are increasingly considered as a potential effective intervention technique when it comes to behavioral change. The results of the current study stress the importance to tailor serious health games in order to be effective, because no effect was found on attitude or eating behavior.
Microencapsulation of Crude Folic Acid Extract from Chayote (Sechium edule Jacq. Swartz) with Ionic Gelation Method
Authors: Purba Johana Novita Paulina , Rusmarilin Herla , Lubis Zulkifli
Published: November 2019

Chayote is a plant which grow and develop throughout the year, contains of  93 mcg/100g folic acid. The aim of this research was to determine the ratio of sodium alginate with pectin and CaCl2 concentration coating to produce microcapsules of crude folic acid extract. Four phases of study was done, namely the manufacture of folic acid extract, manufacture of microcapsules with ionic gelation, analysis of folic acid content in the microcapsules, and the analysis of folic acid after storage of one week. Folic acid extract was made by maceration using alcohol 70% at pH 6, preparation of the microcapsules was using sodium alginate with pectin and folic acid was analysed using HPLC. Folic acid extract showed antioxidant activity of 98,1% with folic acid of 0,16 mg/kg. Microencapsulation of folic acid extract results showed the highest antioxidant activity was formed in alginate ratio of  70% to 30% pectin and CaCl2 concentration of 0.1 M i.e.  62.77 mg/kg. Folic acid is an antioxidant, highest antioxidant value folic acid was analyzed,  treatment was in alginate ratio of 70% to 30% pectin and CaCl2 concenration at 0.1 M i.e. 3.06 mg/kg, after one week at room temperature is became 2.39 mg/kg.
PERBANDINGAN GAMBARAN DARAH ULAR SANCA BATIK (Malayophyton reticulatus) LOKAL JAWA DAN KALIMANTAN
Authors: Raharjo Slamet , Hartati Sri , Indarjulianto Sedarmanto , Widayanti Rini
Published: November 2019

Reticulated python (M. reticulatus) Java and Kalimantan locality highly demand as pet animal. Blood profile has an important role on animal health status. This research was aim to study the blood profile comparison of Java and Kalimantan M. reticulatus. Ten blood samples of Java M. reticulatus and 10 samples of Kalimantan M. reticulatus were used in this study. As much as 1 ml blood sample was collected from ventral coccygeal vein of adult healthy M. reticulatus. Blood sample put into tube with EDTA then analized at Internal Department Laboratory, Faculty of Veterinary Medicine UGM. Based on blood samples analize results, adult healthy Java M. reticulatus shows the higher value on parameters of erytrocyte, leucocyte, PCV, MCH, heterophyl, limphocyte and monocyte, while haemoglobin, TPP, MCV, MCHC, azurofil and monosit were lower than Kalimantan M. reticulatus. There were no significant differences (P>0,05) between blood profile of Java and Kalimantan M. reticulatus. It could be concluded that blood profile of Java and Kalimantan M. reticulatus is not different.
Karakterisasi dan Identifikasi Bakteri Enterobacteriaceae pada Telur Penyu Lekang (Lepidochelys olivacea) asal Lhok Pante Tibang, Banda Aceh
Authors: Risa Nursanty *, Widya Sari, Safranita Risa Nursanty *, Widya Sari, Safranita , Sari Widya , Safranita Safranita
Published: November 2019

The population of olive ridley turtle (Lepidochelys olivacea) are currently thretened with extinction, among the contributing factors is the failure of turtle eggs to hatch. The condition can be caused by the presence of bacterial contamination, especially group Enterobacteriaceae. The purpose of this research was to isolate the group of Enterobacteriaceae bacteria from olive ridley turtle. The sample used were shells from olive ridley turtle eggs comes from natural captivity in Lhok Pante Tibang Beach, Banda Aceh. The research parameters included the number of isolates, macroscopic morphology (shape, edge, elevation, and color of isolates), cell morphology (Gram staining and cell shape), and biochemical tests. Isolation method using spread plate and quadrant method. The isolation results obtained five isolates which had varying macroscopic morphology. The five isolates were Gram negative and formed such as trunk. Identification results found that there were three genus from Enterobacteriaceae videlicet two isolates were Enterobacter, two isolates as Shigella and the other were Klebsiella.
Prevalensi Strain Avian Pathogenic Escherichia coli (APEC) Penyebab Kolibasilosis pada Burung Puyuh
Authors: Prihtiyantoro Wahyu , Khusnan Khusnan , Slipranata Mitra , Rosyidi Imron
Published: November 2019

Avian Pathogenic Escherichia coli (APEC) is a pathogen that causes colibacillosis in poultry, including salpingitis, omphalitis, cellulitis, swollen head syndrome, coligranuloma yolk sac inflammation, and air sacs inflammation. APEC is a zoonotic strain which spread through raw meat and processed meat products of animals and birds. In this research, the isolation and identification of Escherichia coli were done by using selective media MacConkey, Kligger Iron Agar, and Gram staining. Polymerase chain reaction (PCR) was used to analyse genetopically to detect 16SrRNA genes, vt1 genes, and vt2 genes. Thirty one (55,36%) isolates of 56 specimens collected from quail were detected as Escherichia coli. The detection of APEC strains towards 31 Escherichia coli isolates were done by using polymerase chain reaction (PCR) with vt1 and vt2 specific primer. The results showed that 32,26% (10/31) was APEC strains and 67.74% was non-APEC strains. From 10 isolates, 90% had vt1 gene and 10% had vt2 gene. Escherichia coli isolates were found in eyes (32,26%), infraorbital sinus fluid (32,26%), nasal fluid (16,20%), also in lungs, air sacs, ascites, and heart for 3,2% each. The isolates could not be found in the specimens from the skull. As a zoonotic agent, the isolates have an impact on human health.
Plastic Surgeries as Part of the Culture Industry in Jordanian Society: A Qualitative Study in the City of Amman
Authors: Aisheh Yasmin Imad Qarida Abu , Al-Tarawneh Mohammed Fayez
Published: November 2019

The study aimed to identify the reason why females tend to perform plastic surgeries for cosmetic purposes and to identify the social and economic characteristics of the study sample. The study population included females who had at least one cosmetic surgery in Amman. The qualitative approach was used in this study. The study results were based on the following: an effect on the psychological factor, age, scientific and technological development which led to low risk, Media, and means of communication. Social, stereotypical society, friends, relatives and the surrounding environment in increasing the turnout of girls and their orientation towards cosmetic surgery, while there was no trace of each resemblance to a certain figure and the job title to guide the young and attract them to perform beautification.The study also recommended the following: create programs about the risks of plastic surgeries to raise awareness among people, further studies on plastic surgery, as there is a lack of Arabic sources, research and studies on this subject, as there are no statistics for plastic surgeries in Jordan.
TEORIJE, MODELI I PERSPEKTIVE JAVNIH AGENCIJA
Authors: Pejkovic Marko
Published: November 2019

U Srbiji, javne agencije su institucije koje, donedavno, gotovo da nisu bile predmet naučne pažnje. I to malo što su proučavane, one su istraživane isključivo od strane pravnika. Politikoloških radova na temu javnih agencija nema. Iako je pravna nauka markirala položaj javnih agencija u političkom sistemu Srbije i ukazala na potencijalno „preklapanje‒dupliranje” njihovih funkcija sa zatečenim organima uprave kao „unikatno” srpski problem – pun odgovor o genezi, načinu rada i promenama javnih agencija nije dat. To je zbog toga što odgovor na ta pitanja mogu dati samo teorije koje su se razvile direktno ili indirektno u domenu politikologije. Zbog toga će u ovom radu biti prikazane sve glavne teorije, modele i perspektive javnih agencija u savremenoj politikologiji. Ne samo da će na taj način srpski istraživači steći mogućnost da izaberu konceptualni okvir unutar koga će nadalje moći da vode empirijska istraživanja javnih agencija u Srbiji, već će moći i da komparativno istražuju javne agencije. Ovaj članak se u pregledu teorija, modela i perspektiva javnih agencija najviše oslanja na knjigu Kristofera Polita i grupe autora pod nazivom Agencies – How Governments do Things Through Semi-Autonomous Organizations. U vidu uvoda, prvi deo rada je posvećen stanju agencijske tematike u nauci i definisanju pojma javnih agencija, drugi deo pregledu teorija javnih agencija, a treći deo zaključku u kom autor pruža kritički rezime prikazanih teorija, modela i perspektiva.
IZAZOVI OSTVARIVANJA EFIKASNE I DELOTVORNE NADZORNE FUNKCIJE PARLAMENTA SA POSEBNIM OSVRTOM NA INTERPELACIJU
Authors: Pásztor Bálint
Published: November 2019

Predmet rada je analiza pravno-političkih i institucionalnih pretpostavki prevođenja instituta interpelacije iz sadržine ustavnih i poslovničkih odredbi u efikasan i delotvoran mehanizam nadzora rada vlade. Analiza mogućnosti ostvarivanja delotvorne parlamentarne kontrole, mogućnosti usidrenih u realnost skupštinskog života ima za cilj da učini „životnim” institut interpelacije. Da bi se razumela nužnost transformacije interpelacije iz pravnog ideala u praktično-politički mehanizam parlamentarne kontrole analizirani su, u istorijsko-komparativnom kontekstu: nastanak i obeležja nadzorne funkcije parlamenta, jer ne može se govoriti o parlamentarnom sistemu državne vlasti bez kontrolne funkcije koju prevashodno razumemo kao manifestaciju predstavničke uloge parlamenta; prezentovana su različita teorijska viđenja klasifikacije nadležnosti parlamenta; razmatrana je sloboda govora kao pretpostavka ostvarivanja nadzorne uloge parlamenta kao i suštinski elementi interpelacije: pravna priroda, uslovi i posledice podnošenja. U Srbiji, interpelacija iako materia constitutionis, nije zaživela kao delotvorni kontrolni mehanizam rada vlade, te smo posebnu pažnju posvetili formulisanju predloga kako unaprediti interpelaciju i generalno, kontrolnu ulogu Narodne skupštine. U radu su korišćeni različiti metodološki pristupi: istorijski i uporedni metod, kao i egzegetički, u smislu tumačenja različitih pravnih izvora, s tim da je posebna pažnja posvećena analizi, komentarima i tumačenjima određenih ustavnih, zakonskih i podzakonskih, posebno poslovničkih rešenja pravnog poretka Republike Srbije, ali i analizi primera iz naše i strane parlamentarne prakse.
El concepto de la tolerancia religiosa en Chile en la primera mitad del siglo XIX:
Authors: González Pizarro José Antonio
Published: November 2019

The concept of religious tolerance during the so-called Portales regime is examined, putting emphasis on how it was understood by the Church, the liberals of that time, and how it was solved by national governments, from O’Higgins to Montt, within the framework of patronage regime. The context of Chilean diplomatic relations with European countries and their advances in the Latin American context are analyzed to understand the ideological associations with other concepts that turned tolerance into a totalizing matter for the Church, liberals, European diplomacy, and, to some extent accepted by governments in their treaties with European powers.
Plane trusses optimization by means of parametric design and genetic algorithms applying visual programming
Authors: Begliardo Olivero Hugo Félix , Bonelli Hernández Matías
Published: November 2019

The optimization of structures is a wished goal, but it is not always achieved in engineering practice, due to either the large additional effort that it demands or the lack of necessary resources to carry it out. Structural engineers usually use batch procedures, consisting of utilizing the software, in which data are input, running the analysis and evaluating the results, along which it is decided whether the design is accepted or modifications must be made, in which case the process is repeated again. The consequence of this is that the final result, normally, will always be improvable. For that reason, the field of optimization has usually been reserved to the academia. The new currents of structural engineering seek optimization by means of parametric design and evolutionary computing. As an additional contribution to the use of these resources, the objective of this work is to present an algorithm developed through visual programming for sizing, shape and topology optimization of plane trusses of the classic Howe, Pratt or Warren typologies, and to highlight the advantages that the use of this resource provides for the professional work of structural engineers, since it allows them to develop their own algorithms without the need of previous knowledge of programming, and to achieve economic and environmental benefits from saving materials. All this configures a clear transfer of the advances of computer technology to professional practice, extending the frontiers of the academic sphere. As an example of application, a truss analyzed by traditional methods, without optimizing, and the same truss optimized with the aforementioned algorithm, are compared.
Durabilidad del concreto con agregados de alta absorción
Authors: Solís Carcaño Rómel Gilberto , Alcocer Fraga Miguel Ángel
Published: November 2019

Durability of concrete constructions is equally important as mechanical resistance, since it determines the capacity to withstand the environmental conditions to which the construction will be subjected for several decades. Most of concrete durability problems are associated with its porosity and permeability, properties on which the ability to allow the flow of liquids and gases depends. The aim of the present work was to evaluate the durability of the concrete manufactured with limestone aggregates of high absorption and water/cement ratio in a range of 0.40 to 0.70, by means of the resistance to the compression, the porosity, the permeability to the air, the sorptivity and the electrical resistivity. Results showed that this type of concrete can have a good durability in aggressive environments with an A/C of 0.40, and in environments of moderate aggressiveness with an A/C of 0.50.
Control PI difuso de un sistema de levitación magnética mediante un sistema embebido
Authors: Lozano Hernández Yair , Gutiérrez Frías Oscar Octavio , Villafuerte Bante Mario
Published: November 2019

In the present work, the design and implementation of a control scheme is presented. The aim of the control scheme is to perform regulation and trajectory tracking tasks in the position of a magnetic levitation system, which acts by electromagnetic repulsion. Such levitation system consists of a beam operated by an active magnetic bearing in pendular configuration. Although the Proportional Integral Derivative (PID) controller shows arithmetic simplicity, ease of use, high robustness and error equal to zero in stable state (Pal & Mudi, 2008), the magnetic levitation system mathematical model is highly non-linear and is subject to uncertainty or variation of its parameters. Therefore, the PID control does not guarantee the fulfillment of trajectory tracking tasks (Precup & Hellendoorn, 2011). In summary, a diffuse PI is used due to the system non-linear dynamics and the hysteresis present in the electromagnet. The controller design was made with the following methodology: the mathematical model and the non-linear characteristics of the system are analyzed; the universes of error discourse (derived from error and control action) are experimentally measured. The experimental data was used for the fuzzification, defuzzification, statement of the rules and controller gains. The implemented rules were designed for a PD-Fuzzy in which a numerical integration of the control action was applied, obtaining a Fuzzy PI. Finally, the implementation was made on the STM32F407G-DISC card, which was programmed with MATLAB-Simulink software tools. The experimental results show that the proposed controller works even below the horizontal, where the behavior can show singularities or physical problems such as magnetization. In compliance with the stated objectives for a range of -5 to 10 radians, these results are maintained even in the presence of disturbances, demonstrating the feasibility of the controller.
Análise quantitativa das sorologias das Hepatites B e C em 2017, em uma capital do Nordeste
Authors: Costa Emannuelle Pessoa Costa Pessoa , Coêlho Hitalo Roberto de Araújo , Fernandes Alice Januário Guedes , Ferraz Jéssica Ohana de Alencar , Silva Moura Laísa Sheffany da Cruz , Silva Lara Kamylla Queiroz , Da Silveira Luana Nascimento , Sousa Mariana de Andrade , De Souza Suyene Maria Lima , Da Silva Fabiano Vieira , Da Silva Machado Herion Alves , Marques Rosemarie Brandim , Martins Liline Maria Soares
Published: November 2019

As Hepatites Virais dos tipos B e C são uma preocupação constante de saúde pública, devido às suas manifestações agudas e possibilidade de cronificação. Muito se fala sobre as melhores formas de se dar seguimento a um paciente diagnosticado com Hepatite Viral, porém pouco se aborda sobre a eficácia e as rotinas de diagnósticos que são realizadas, as quais refletem na observação de casos de subnotificação e cronificação de quadros agudos que, caso tivessem adequado diagnóstico e tratamento, poderiam não se direcionar para a cronificação. Foram analisados 4.294 exames sorológicos realizados em laboratório de referência em Teresina-Pi. Dos exames analisados, 3.333 eram de avaliação imunológica (bancada), enquadrando-se como as pesquisas de rotina no caso de pacientes com quadros clínicos e epidemiológicos compatíveis. Dos 4.294, 3.248 foram dados como não reagentes, figurando uma alta taxa de não diagnóstico. Os resultados do presente estudo nos permitem concluir que há uma deficiência significativa na atualização de dados nos meios oficiais de acesso aos mesmos, evidenciando uma demonstração destoante da realidade epidemiológica da cidade de Teresina (PI) em relação aos casos de Hepatite B e Hepatite C.
PRÓTESE DENTÁRIA METAL FREE
Authors: Spezzia Sérgio
Published: November 2019

Resumo Os materiais protéticos detém um papel de relevância, a escolha de um determinado material para uso deve levar em conta vários fatores. Muitas vezes, têm-se um material resistente, mas com poucas características favoráveis quanto a opalescência e translucidez. Deve-se considerar materiais restauradores com propriedades que possibilitem restituir a função e a estética do sorriso. Restaurações livres de metal também chamadas de metal free constituem um desses materiais, que são escolhidos para uso, principalmente, devido características estéticas favoráveis. O sistema metal free permite a obtenção de características estéticas similares as da dentição, no que tange a textura, cor, translucidez e opalescência. O objetivo deste artigo foi verificar como pode-se empregar as próteses dentárias metal free nos procedimentos odontológicos. A procura pelas restaurações cerâmicas livres de metal pelos pacientes tem aumentado nos consultórios odontológicos, uma vez que as mesmas possibilitam a obtenção de uma estética dental satisfatória. Pode-se indicar o emprego das próteses metal free em indivíduos adultos, que detém higienização bucal satisfatoriamente realizada. Pode-se utilizá-las no planejamento e instalação das restaurações tipo overlay, onlay, inlay, para facetas estéticas, entre outros. O planejamento odontológico deve ser executado corretamente e para que obtenha-se desfecho estético favorável, os passos ou procedimentos clínicos para instalação das próteses livres de metal devem ser realizados sequencialmente. Palavras-chave: Sorriso. Estética. Cerâmica. Planejamento. Keywords: Smiling. Esthetics. Ceramics. Planning.
A EXPERIÊNCIA DO PROJETO ABEPSS ITINERANTE: A ATUALIDADE DO PROJETO DE FORMAÇÃO PROFISSIONAL FRENTE À CONTRARREFORMA DA EDUCAÇÃO.
Authors: Abreu Maria Helena Elpidio
Published: November 2019

O artigo se apresenta como parte da sistematização do Projeto intitulado ABEPSS Itinerante, implementado pela Associação Brasileira de Ensino e Pesquisa em Serviço Social (ABEPSS). Parte da experiência como docente e da análise de elementos avaliativos organizados nos relatórios regionais da Entidade. Trata-se de uma expressão ou apreensão limitada da magnitude do que representou a elaboração, a materialização e os desdobramentos do projeto nas suas dimensões política e pedagógica. Buscou-se articular os pressupostos teóricos que norteiam a análise da realidade e o projeto de formação profissional do Serviço Social no contexto da contrarreforma do ensino superior com os objetivos, possibilidades e desafios levantados com a materialização do Abepss Itinerante. Interessa-nos realçar a experiência como estratégia na defesa Formação Profissional consubstanciada nas Diretrizes Curriculares. Palavras-chave: Serviço Social. Formação Profissional. Projeto ABEPSS Itinerante.  Contrarreforma do ensino.
ÉTICA E SERVIÇO SOCIAL: UM ITINERANTE CAMINHAR
Authors: Silva de Sousa Adrianyce A. , Morais dos Santos Silvana Mara , Cardoso Priscila
Published: November 2019

O presente artigo tem por objetivo discutir, a partir da experiência do Projeto Itinerante desenvolvido pela Gestão da ABEPSS 2011-2012 em parceria com o CFESS, a questão da ética na formação profissional em Serviço Social na atualidade. Para tanto, a elaboração deste material partiu da compilação e sistematização dos Relatórios dos Regionais da ABEPSS das experiências do Projeto ABEPSS Itinerante no que se refere ao módulo 04 “A Ética na Formação Profissional”. Assim, apontamos aqui um conjunto de questões que atravessam e problematizam a formação dos futuros assistentes sociais a luz de uma necessária reflexão ética.
La imagen de Claudio López, segundo marqués de Comillas
Authors: ARAMBURU-ZABALA HIGUERA Miguel Ángel
Published: November 2019

Claudio López Bru, segundo marqués de Comillas, muestra en el arte la contradicción entre el rechazo íntimo a la exhibición pública de los honores recibidos y la necesidad de mostrarse en cada ocasión de acuerdo a las reglas sociales usualmente aceptadas y, sobre todo, el deber de honrar a las instituciones con las que se relaciona, sea la Iglesia, la monarquía, la familia o sus empresas. El traje de gala, uniformes y medallas distinguen sus retratos de los mucho más austeros de su padre, y la idea religiosa está siempre presente en el arte que patrocina, cercano ideológicamente al Círculo de San Lucas de Barcelona.
Agustín Ibarrola: exposiciones nacionales e internacionales (1963-1969)
Authors: LORDUY-OSÉS Lucas
Published: November 2019

El pintor y grabador vasco Agustín Ibarrola fue condenado en el año 1962 a nueve años de reclusión por su activismo político en contra del régimen franquista. Durante su internamiento en la prisión de Burgos realizó una obra artística clandestina de indudable valor testimonial, que gracias a una red de apoyo del Partido Comunista de España y otras organizaciones internacionales en pro de los derechos humanos sería expuesta en Londres, Amsterdam, Bolonia, París, Frankfurt y otras ciudades europeas entre 1963 y 1969. Estas exposiciones solo fueron conocidas en España a través de Radio España Independiente, emitiendo desde Bucarest.
Los Documentos de Leonor de Portugal, reina de Aragón (1347-1348), contenidos en su único registro cancilleresco.
Authors: RODRÍGUEZ LAJUSTICIA Francisco Saulo
Published: November 2019

Leonor de Portugal (1328-1348) fue la única reina de Aragón de origen luso. Segunda mujer de Pedro IV el Ceremonioso, su reinado comprende desde finales de 1347 hasta octubre de 1348, momento en el que murió a causa de la Peste Negra. En el Archivo de la Corona de Aragón se conserva un registro cancilleresco, el número 1562, que contiene 57 documentos emitidos por la reina cuya transcripción se ofrece en este artículo.