bluuebunny/crossref_metadata_2025 huggingface dataset:
ZONASI KONDISI AIR TANAH TERHADAP GERAKAN TANAH DAERAH MADUKARA – BANJARNEGARA PROVINSI JAWA TENGAH
Authors: Asseggaf Abdurrachman , Nandiwardhana Supandya , Lestari Arini Dian
Published: February 2022

Besarnya jumlah air sangat mempengaruhi oleh kondisi topografi, litologi permukaan, dan hidrogeologi. Kondisi geologi Banjarnegara sangat bervariasi dan mempunyai karakterisasi sendiri, dengan demikian jumlah air juga sangat bervariasi. Hal ini disebabkan kondisi litologi tertentu mampu menampung air dalam jumlah yang tertentu pula. Perbedaan ini menyebabkan hidrogeologi Banjarnegara mempunyai perbedaan pula, hal ini diyakini telah mengalami perubahan dari kondisi alamiahnya, sebagai akibat pengambilan airtanah selama ini. Pergerakan tanah juga bisa dipengaruhi oleh kondisi airtanah pada daerah Banjarnegara Kecamatan Madukara karena memiliki karakteristik batuan yang berbeda dimana batuan pada daerah ini tidak memiliki karakteristik yang sama semua dan memiliki perbedaan karakteristik, perbedaan karakteristik ini yang bisa menyebabkan pergerakan tanah yang dipengaruhi kondisi airtanah.Pada daerah penelitian berada didaerah banjarnegara kecamatan madukaran dimana dekat dengan daerah wisata dieng yang terletak pada titik koordinat 109°45'36" BT - 109°45'3.6" BT dan 7°21'46.8" LS - 7°22'19.2" LS dilakukan penelitian tentang kerentanan gerakan tanah yang dipengaruhi oleh pengaruh kondisi airtanah, tujuannya untuk mengetahui airtanah terhadap Gerakan tanah pada daerah penelitian. Metode yang dilakukan pada penelitian ini adalah metode zonasi, metode scoring, metode overlay terdapat 5 faktor yaitu litologi batuan, hidrogeologi, kemiringan lereng, curah hujan, dan dari tata guna lahan. Ke lima faktor ini memiliki kaitan yang erat dalam mempengaruhi kerentanan gerakan tanah pada daerah yang diteliti. Dilakukan anisis dari data sekunder yang kemudian dilakukan pembobotan pada setiap faktor yang ada dan dilakukan pengolahan data dengan menggunakan software arcgis. Setiap faktor dibuat peta penyebarannya dan dari kelima peta tersebut dilakukan overlay sehingga menghasilkan zonasi kerentanan gerakan tanah. Dari analisis yang telah dilakukan didapatkan peta zonasi kerentanan gerakan tanah yang dibagi menjadi 4 yaitu berpotensi rawan, berpotensi sedang, berpotensi aman, berpotensi sangat aman.
Area Identification Of Catchment Areas Using Far Sensing And Gis Applications In East Jakarta
Authors: Yuda Himmes Fitra , Anugrahadi Afiat , Rahmawati Puspita Dinda
Published: February 2022

The presence of catchment areas is needed. Besides its function for groundwater conservation, this area also is used to reduce flood risks. The need for houses also encourages people to use qualified Catchment areas to be used as houses and does not consider its natural factors. It happens a lot in suburban areas such as East Jakarta that in early 2020 this area becomes one of the most affected areas due to the flood in DKI Jakarta. Due to the world pandemic, Covid-19, direct field research is hard to carry out, so this research using remote sensing applications and geographic information systems to identify areas that qualify as water catchment areas. In practice, it uses secondary data sourced from national institutions and agencies with direct access to the data. The results showed that 12,36% of the research areas did not meet the requirements as Catchment areas, 68,01% were sufficiently eligible, and 19,63% were highly qualified. However, in its utilization, only 22.06% of the total research area currently plays an active role as groundwater catchment areas because of the land cover dominated by built-up land. It can lead to various risks as flooding or a reduction in the volume of groundwater.
STOCHASTIC POROSITY MODELING IN VOLCANIC RESERVOIR JATIBARANG FORMATION
Authors: Widianto Eko , Herdiansyah Firman , Burhannudinnur Muhammad , Prakoso Suryo , Benyamin Benyamin
Published: February 2022

Jatibarang Formation known as interesting volcanic reservoir in North West Java Basin. The reservoir was characterized by altered and naturally fractured that has significantly producing light oil. The volcanic Jatibarang reservoir consist of 3 volcanic cycles that are cycle 1, cycle 2 and cycle 3 with 16 faults configuration. Total and Fracture porosity modeling was conducted to determine secondary porosity distribution using stochastic method. Lithofacies and property lateral variation were generated to visualize geological model. Total porosity was estimated using formation evaluation. Natural subsurface fracture has been identified by bore hole image (formation micro imager) and geophysical log from several wells in the Jatibarang Field. It has provided both lithology and property reservoir information. Lithofacies tuff and non tuff model has been used as a constrait to distribute pore pressure and bulk modulus. Then, porosity model was distribution using the collocated-co kriging method. The purpose of this study was to determine the distribution of total and fracture porosity of the Jatibarang volcanic reservoir.
SLAM in Duckietown Simulator Using the OpenVSLAM Framework
Authors: Devyatovskaya A. D. , Biryuchkov N. E. , Liakh T. V. , Chaika K. V.
Published: February 2022

The article is devoted to evaluating the applicability of SLAM frameworks for the task of mobile robots of the Duckietown project. The paper provides a comparative analysis of existing SLAM algorithms and frameworks and se-lects frameworks taking into account all the constraints imposed by the project robots. The practical results of testing OpenVSLAM framework on the Duckietown environment and Duckietown simulator data are presented.
Methods for Protecting Control Commands in the Instrumental Environment for Automated Process Control Systems
Authors: Blagodarny A. I. , Pishchik B. N.
Published: February 2022

The paper discusses methods that ensure the execution of only correct and legal control commands in the process control system. Protection of the integrity of the APCS software at all nodes of the industrial network, including protection against unauthorized substitution, is carried out by checking the control parameters of the software during their startup. Protection of control commands from distortions during transmission over the network is realized by double coding at different levels of the system. Protection against the submission of unauthorized control commands to technological equipment is carried out by recognizing these commands in the lower-level subsystem and comparing their current characteristics with the control ones.

A certain contribution to the safety of the process control system is made by the use of a secure execution environment – OS CentOS 7.
Development of Chatbots to Support Web Site Content Search Based on Thematic and Genre Characteristics
Authors: Rublev V. D. , Sidorova E. A.
Published: February 2022

The paper considers an approach to creating intelligent assistants in the form of chatbots that support information search based on preliminary genre and thematic clustering of website content. The tasks of finding the necessary in-formation and providing information support to the user, organizing feedback to improve the quality of the search are being solved. A feature of the approach is the use of genre models developed for a given type of resource (educational, informational, etc.), on the basis of which genre structuring of the content of a particular site is carried out. The resulting genre structures allow you to more accurately determine the boundaries of thematic clusters related to the topic of the user's search query. To provide feedback to the user, a simple script has been developed that allows not only to clarify the request, but also to implicitly get information about what exactly did not suit the user in the resulting out-put. An experimental study was conducted on the Telegram platform, the results were compared with the Yandex search engine.
Development of a Finite Element Method and Its Application in a CAD
Authors: Soloviev A. N. , Kirichevsky R. V.
Published: February 2022

The presented review of existing domestic and foreign CAD systems showed that the use of FEM in their structure remains quite relevant before other methods in the speed of calculations, sufficient accuracy and software implementation in the CAD structure. To solve the problems of mechanics of elastomers and composites based on them, an over-view of the developed domestic software MIRELA+ is presented in more detail. This complex solves many problems of solid mechanics: it has a special focus on solving problems of dissipative heating, parameters of fracture mechanics of massive elastomeric structural elements and thin-layer rubber-metal elements with cracks with changing physical, mechanical and thermophysical parameters under cyclic deformation. Not many of the domestic programs can implement this, and licenses for foreign programs cost tens of thousands of dollars.

This paper also presents methods of discretization by finite elements and an algorithm for constructing a system of re-solving equations used in MIRELA+, expressions for determining the components of the coordinate transformation tensor, the strain tensor at the FE centers in a Cartesian coordinate system. Examples of visual representation in a three-dimensional image using a color picture are given, where each shade or color corresponds to a certain range of numerical values of the corresponding function.
Development of Intelligent SPARQL Query Editor
Authors: Turova I. A. , Postanogov I. S.
Published: February 2022

The paper discusses the development of SPARQL query editor. This is an actual question because of the growth of Semantic Web data – the data presented in RDF/OWL formats. A comparative analysis of different types of editors and their main features is provided. In this paper, we propose a description of a SPARQL editor that combines three most useful features: intelligent completions, query visualization comparison of query results provided by different reasoners or without them. The editor provides SPARQL support as LSP service, this approach is considered a modern way to implement language support. This paper also presents the editor’s screenshots.
In memoriam Prof. Dr. dr. Saptawati Bardosono, MSc
Authors: Pansawira Pittara , Sutanto Luciana Budiati
Published: February 2022

The passing of Prof. Saptawati Bardosono on October 15th last year was a great sadness and loss for the entire scientific community, especially nutrition-related. It was also an immeasurable grief for us, the editorial team of World Nutrition Journal.
Flavonoid intake and its correlation to malondialdehyde serum among reproductive-aged women with obesity
Authors: Nasruddin Nina Indriyani , Novi Silvia Hardiany  , Wiji Lestari
Published: February 2022

Background: Obesity modulates oxidative stress and can be detected by examining malondialdehyde (MDA) serum levels. Flavonoids are natural bioactive ingredients that can be found in various types of vegetables and fruits that function as antioxidants to suppress that oxidative stress.

Objective: This study aimed to determine the correlation between flavonoid intake and MDA serum levels in obese women of reproductive age.

Methods: This cross-sectional study was conducted in Kendari, Indonesia from April to October 2021. The purposive sampling method was used to obtain 88 subjects who met the research criteria. Data were collected through interviews covering flavonoids intake using validated SQ-FFQ. Anthropometric measurements were performed to assess nutritional status, and laboratory tests were applied to determine MDA serum levels.

Results: The average intake of flavonoids in the subjects was 142,26 ± 56,53 mg per day. Meanwhile, the average MDA serum level in the subjects was 2.16 mol/L, ranging from 1.09 nmol/ml to 6.71 nmol/ml. There was no significant correlation between total flavonoid intake and MDA serum levels in obese women of reproductive age (r=0,188, p=0,079). However, there was a weak correlation between the intake of flavonoid subclasses, namely flavan-3-ols/flavanols and MDA serum levels (r=0.325, p=0.002).

Conclusion: We conclude that there was no correlation between total flavonoid intake and MDA serum levels. However, there was a correlation between flavan-3-ols/flavanols and MDA serum levels in the subjects.
Mother’s Coping strategies toward Food Insecurity during COVID-19 Pandemic: A Review Article
Authors: Vantono Sherly Ardi , Bardosono Saptawati , Wiradnyani Luh Ade Ari
Published: February 2022

The COVID-19 pandemic has impacted many aspects of the country, including the economy and health care.  Food insecurity is increasing, causing harm to children’s nutrition and development. As a result, mother must deal with food insecurity to providing a balanced diet for her children aged 6 to 23 months. This study aims to review the possible mother’s coping strategies used toward food insecurity to maintain child nutrition during the COVID-19 pandemic. To review the literature, the researcher utilized search engine such as PubMed, ScienceDirect, Oxford journal, and British Medical Journal. "COVID-19", "Coping Strategies", “Food Security”, and "Child” were among the keywords chosen by the researcher. After filtering with the several criteria, the 17 articles were reviewed. Based on this paper review, we know that during the COVID19 pandemic, there is a coping strategy that assist mother to maintain their child nutrition. To address the problem of food insecurity, the possible mother’s coping strategy used are adaptive coping strategies such as home-cooked meals, financial support, and receiving food assistance.
Repercussões clínicas e terapêuticas da COVID-19 em portadores de doenças reumáticas
Authors: Castro Luana Fernandes da Silva Oliveira , Pitanga Lorena Sipauba , Fernandes Fernanda Rodrigues Mangabeira , Caselato Maria Letícia Lopes Mol , Barbosa Juliano Passos , Vinhal Letícia Dutra Magalhães , Rocha Renan Vezolle , Rocha Ellen de Lima , Parca Leonardo Martins , Gois Eliana Teles de
Published: February 2022

Objetivo: Analisar as repercussões clínicas e terapêuticas em portadores de doença reumática diante a coinfecção por SARS-CoV-2. Revisão bibliográfica: O surgimento do SARS-CoV-2 em dezembro de 2019 gerou uma mobilização internacional da comunidade científica a fim de elucidar repercussões clínicas e farmacológicas da COVID-19. Em portadores de doenças reumáticas, apesar de lesão tecidual relacionada a um estado de hiperinflamação do organismo pela COVID-19, estes apresentam um amplo espectro de disfunção imunológica, tornando a gravidade desta infecção altamente variável e potencialmente de maior risco. Esta condição determina certo desafio, visto que infecções graves são formalmente conhecidas como causa de mortalidade em diversas condições reumáticas. Considerações finais: A revisão visa auxiliar a prevenir complicações e ampliar a segurança aos portadores de doenças reumáticas que, apesar de dados majoritariamente preliminares e observacionais, corroboram com um desfecho favorável embora algumas observações acerca do tratamento devem ser salientadas além de seus potenciais fatores de risco.
Professor T. Gopinathan
Authors: Pavithran K.
Published: February 2022

Thekkepat Gopinathan was the former Director and Professor and Head of the department of dermatology and venereology, Government Medical College, Calicut. Due to his hard work and dedication, the department of dermatology of Calicut Medical College grew step by step and became a postgraduate training center in the year 1972. He was the recipient of many awards that included Dr. Ambady Oration Award (1980), American Academy Award (1983), Indian Medical Association (IMA) AMS Award (1982), Fellow Madras Medical College Award (1985), Best Doctor Award, Calicut IMA (1997), and Prof. K. C. Kandhari Foundation Award (2001). He was the National President of Indian Association of Dermatologists, Venereologists, and Leprologists and had been the Honorary Secretary and President of Calicut, IMA. Professor T. Gopinathan was one of the main persons who took initiative in implementing the idea of starting an online journal as he felt that there was a need for better “group-specific communication” among the growing number of young practicing dermatologists in India. This idea later materialized as the Indian Dermatology Online Journal. The legend that he is, he will be remembered and revered by all who ever interacted with him.
دور كلية التربية الإسلامية في نشر علوم القرآن وقراء دور كلية التربية الإسلامية في نشر علوم القرآن وقراءاته
Authors: Firdaus Muhammad , Ali Fitriana Rusyai , Hukmi Nurul
Published: February 2022

علوم القرآن وقراءاته تعد أصلا لجيع المواد الدراسية، وغيابها من الجامعات غياب لأصولها، فإن أصول الجامعات مهما كانت تخصصاتها هي تطبق المهارات وصلتها بالقرآن الكريم، وفي هذه العجالة يتركز الباحث في مهارة أحكام تلاوة القرآن الكريم وهي مجال علم القراءات. وإن جميع الكليات في الجامعات تفتقر إلى الدراسات القرآنية مهما تناءت تخصصاتها، ولو على سبيل التبرك بالقرآن الكريم، فإن الملائكة تحف الدارسين المجتمعين على دراسة كتاب الله، وتنزل عليهم السكينة والرحمة، ويذكرهم الله فيمن عنده، ولو لم يكن إلا هذا الأمر لكفى. وكيف بالقرآن الكريم وقد حوى من العلوم والمعارف ما لا ينفد، ولا يخلُق على كثرة الرد، ولا تنقضي عجائبه، ولا تزال تتجدد به العلوم والمعارف. الدراسات القرآنية وما زخر فيها من العلوم، دعانا إلى النظر في الآيات الآفاقية والأنفسية، فإنه لم يقف بنا عند حد الاعتبار والاتعاظ بالظواهر والصور والأشكال فحسب، وإنما أراد إلى ذلك استكشاف المستور، واستكناه الأسرار؛ فتجعل دراستها ضرورية حتمية تقتضيها طبيعة المجتمع الإسلامي، فلا تقبل التردد ولا المناقشة، وتكون امتدادا للزوايا التي كانت تؤدي هذا الغرض على أكمل الوجوه. وتقوم بهذا الغرض الكفائي، واعتبر الباحث أن وجود علوم القرآن وقراءاته في الجامعات كوجود المسجد سِيّان، فهما متلازمان، العناية والاهتمام بها كالعناية والاهتام به، وبالعكس التقصير فيها كالتقصير فيه. وكان من الواجب المؤكد الذي لا يختلف فيه اثنان أن لا تخلو جامعة من الجامعات من دراسة القرآن وقراءاته.

الكلمات المفتاحية: دور كلية التربية الإسلامية، نشر علوم القرآن وقراءاته
ANALYSIS OF STUDENT RESPONSES IN LEARNING WITH ANDROID-BASED MEDIA
Authors: Chosi Falasifah Hasyim , Fransisca Malia
Published: February 2022

The author will try to do research by developing android-based interactive learning media on BTA learning materials, the author wants to try to find out the response of UIN SAIZU students to the learning media. This study aims to determine student responses to android-based interactive learning media at UIN SAIZU by using the observation method and learning test results. Data collection teaching. The results of the study were obtained based on the results of students’ responses to learning media based on Android on BTA material getting an average percentage of 78.21% in the first observation test with good categories and observation test. The research will try to prove that Android-based BTA learning is very effective because it can be used for all circles, both students and people who are very busy because learning can be done anywhere besides being practical, Android can be used for all positive things. conclusions can be drawn from this discussion as follows:

Applications for learning tajwid based on android can be used by Muslims as an alternative to learning tajwid independently.

With the application of learning tajwid which is equipped with examples of images and sounds, as well as quizzes to test abilities, users are expected to be able to maximize this mobile application as a medium for learning tajwid that is easy to use and easy to reach.

Tajweed science applications can be run via smartphones with the Android operating system.

The application of tajwid is made using the Java programming language and designed with an easy display.
Streifenförmige Ablagerung des Reaktionsprodukts bei einer Gasphasenreaktion
Authors: Bützer Peter
Published: February 2022

The gas-phase reaction of NH3 with HCl in a glas tube (length 150 cm, diameter 1–6 cm) leads to solid depositions of NH4Cl on the glaswall, with a regularpattem of stripes. The peculiar structure is also observed with other volatile reactants leading to a
salt as the only solid product. Variations of tubediameters and temperatures indicate a broad validity of the observations.
Oxidative Coupling of α,ω - Di(cyclopentadienyl)alkyl-diides
Authors: You Shaochun , Gubler Matthias , Neuenschwander Markus
Published: February 2022

The CuII-induced oxidative coupling of α,ω-di(cyclopentadienyl)alkyl-diides 6 (n = 2 to 5) – as well as of 1,1,2,2-tetramethyl derivatives 10 and 13 of 6a (n = 2) – has been investigated in view of pertinent questions concerning the 'coupling mode' (e.g. intramolecular vs. intetmolecular coupling), as well as regioselectivity and stereoselectivity of the coupling reaction. As far as the 'coupling mode' is concerned, intermolecular coupling 6 ? 8 strongly dominates over intramolecular coupling 6 → 7 (Scheme 2) and the yields of intramolecular coupling products strongly decrease from 7% (7a, n = 2) to 1% (7b, n = 3) to traces (7c, 7d, n = 4,5). It is interesting to note that intramolecular coupling may be considerably enhanced by replacing the H-atoms of the CH2CH2 bridge of 6a (n = 2) by Me groups (see 10 → 11 and 13 →14 + 15, (Scheme 4). As far as regioselectivity is concerned, intramolecular coupling of 1,2-di(cyclopentadienyl)ethane-diides, 6a, 10, and 13, proceeds as a clean 2,2'-coupling of the cyclopentadiene rings within the limits of NMR identification. Furthermore, the couplings 6a → 7a and 10 → 11 (as well as 13 → 14 + 15) proceed stereoselectively to give the C2-symmetrical cyclohexanes 7a and 11 with a fixed chair conformation.
Epulis Fissuratum
Authors:   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco, JK Belha , M Bagui ,   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco, S Chbicheb ,   Department of Dentistry Faculty of Dental Medicine Rabat, Morocco, M Sakout ,   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco
Published: February 2022

A 47-year-old patient with no history in her medical history presented to the department with unimaxillary edentulousness rehabilitated by an ill-fitting prosthesis. Intraoral, we note the presence of a sessile leaflet lesion characteristic of the “double lip” appearance in the maxillary mucosa. The treatment consisted of surgical excision of the lesion + muccoperiosteal sutures + tissue conditioning by the KER FITT + periodic checks + creation of a new prosthesis.
Corrective Surgery and Laser ND-YAG
Authors:   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco, M Bagui , JK Belha ,   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco, L Fajri ,   Department of Dentistry, Faculty of Dental Medicine, Rabat, Morocco, M Sakout ,   Department of Dentistry, Military Hospital Mohammed V Rabat, Morocco
Published: February 2022

Epulis fissuratum is a mucosal hyperplasia that result from chronic irritation induced by a poorly fitting prosthesis. It is a pseudotumor sitting in the vestibule of the jaw; and composed of several layers. This lesion impinges on the prosthetic balance and requiring a pre-prosthetic surgical time. The extent of the hyperplasia in this case makes it impossible to take an accurate impression for performing a cicatrisation guiding prosthesis. Total surgical excision of the lesion was performed followed by a subperiosteally vestibule extension. At the final, an application of laser ND-YAG with the aim of coagulation, bio stimulation, limiting the post-operative consequences and fast healing (Figure 1 and 2).
Assessment Sheet to Determine Whether Fixed Implant Prostheses Should be Replaced with Implant Overdentures in the Elderly
Authors:   Clinical Implant Society of Japan, Kashiwa, Chiba, Japan, J Tanaka , Y Suzuk ,   Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan, C Ohkubo ,   Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan
Published: February 2022

At a certain stage before a patient becomes unable to make hospital visits, replacement of fixed implant prostheses with Implant Overdentures (IOD) with simply structured attachments is a useful countermeasure against problems of fixed implant prostheses associated with aging and for maintaining a good oral environment. We investigated an evaluation method to determine whether to replace fixed implant prostheses with IOD in patients undergoing treatment with fixed implant prostheses.
Bending a Photonic Wire into a Ring
Authors: Gotfredsen Henrik , Deng Jieren , Van Raden Jeff , Righetto Marcello , Hergenhahn Janko , Clarke Michael , Bellamy-Carter Abigail , Hart Jack , O’Shea James , Claridge Tim , Duarte Fernanda , Saywell Alexander , Herz Laura , Anderson Harry
Published: February 2022

Natural light harvesting systems absorb sunlight and transfer its energy to the reaction centre, where it is used for photosynthesis. Synthetic chromophore arrays provide useful models for understanding energy migration in these systems. Research has focussed on mimicking rings of chlorophyll molecules found in purple bacteria, known as ‘light-harvesting system 2’. Linear meso-meso linked porphyrin chains mediate rapid energy migration, but until now it has not been possible to bend them into rings. Here we show that oligo-pyridyl templates can be used to bend these rod-like photonic wires, to create covalent nanorings. The macrocycles consist of 24 porphyrin units, with a single butadiyne link. Their elliptical conformations have been probed by scanning tunnelling microscopy (STM). This system exhibits two types of excited state energy transfer processes: (a) from the central template to the peripheral porphyrins and (b) from the 24 light-absorbing porphyrin units to the π-conjugated butadiyne-linked porphyrin dimer segment.
Bioorthogonal, fluorogenic targeting of voltage-sensitive fluorophores for visualizing membrane potential dynamics in cellular organelles
Authors: Klier Pavel , Gest Anneliese , Martin Julia , Roo Ryan , Navarro Marisol , Lesiak Lauren , Deal Parker , Dadina Neville , Tyson Jonathan , Schepartz Alanna , Miller Evan
Published: February 2022

Electrical potential differences across lipid bilayers play foundational roles in cellular physiology. Plasma membrane voltage is the most widely studied; however, the bilayers of organelles like mitochondria, lysosomes, nuclei, and endoplasmic reticulum (ER) also provide opportunities for ionic compartmentalization and the generation of transmembrane potentials. Unlike plasma membranes, organellar bilayers, cloistered within the cell, remain recalcitrant to traditional approaches like patch-clamp electrophysiology. To address the challenge of monitoring changes in organelle membrane potential, we describe the design, synthesis, and application of LUnAR RhoVR (Ligation Unquenched for Activation and Redistribution Rhodamine based Voltage Reporter) for optically monitoring membrane potential changes in the endoplasmic reticulum (ER) of living cells. We pair a tetrazine-quenched RhoVR for voltage sensing with a transcyclooctene (TCO)-conjugated ceramide (Cer-TCO) for targeting to the ER. Bright fluorescence is observed only at the coincidence of LUnAR RhoVR and TCO in the ER, minimizing non-specific, off-target fluorescence. We show that the product of LUnAR RhoVR and Cer-TCO is voltage sensitive and that LUnAR RhoVR can be targeted to intact ER in living cells. Using LUnAR RhoVR, we use two-color, ER-localized, fast voltage imaging coupled with cytosolic Ca2+ imaging to validate the electroneutrality of Ca2+ release from internal stores. Finally, we use LUnAR RhoVR to directly visualize functional coupling between plasma-ER membrane in patch clamped cell lines, providing the first direct evidence of the sign of the ER potential response to plasma membrane potential changes. We envision that LUnAR RhoVR, along with other existing organelle-targeting TCO probes, could be applied widely for exploring organelle physiology.
Clusteroluminescence in Maleimide: from Well-Known Phenomenon to Unknown Mechanism
Authors: Xie Yuan , Liu Dan , Zhang Haoke , Wang Dong , Zhao Zheng , Tang Ben Zhong
Published: February 2022

Maleimide compounds have a long history related to colour reactions. It has been reported that maleimide yields bright colour when it reacts with basic reagents. Inspired by its colour formation, we investigated the maleimide polymer produced by an organic base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). The resultant polyimide contains exceptional fluorescence, which is virtually non-emissive in dilute solutions but exhibits strong pink emission (430nm and 580nm) in the concentrated solution and solid state. The intense colour comes from such a simple chemical structure, the unconventional fluorophore can be undoubtedly categorized into clusteroluminogens. By controlling the organic base amount, the intensity ratio of purple and orange-red emission can be controlled. The interaction between maleimide and base is rapid, and it can be achieved in the solid-solid interface or solid-gas interface. The aim herein is to highlight the recent observation and hold strong implications for further potential applications in anti-counterfeiting, gas sensors.
PaRoutes: a framework for benchmarking retrosynthesis route predictions
Authors: Genheden Samuel , Bjerrum Esben
Published: February 2022

We introduce a framework for benchmarking multi-step retrosynthesis methods, i.e. route predictions, called PaRoutes. The framework consists of two sets of 10,000 synthetic routes extracted from the patent literature, a list of stock compounds, and a curated set of reactions on which one-step retrosynthesis models can be trained. PaRoutes also comes with scripts to compute route quality and route diversity quantities that are important for comparing methods. We use the PaRoute framework to compare three methods implemented in the AiZynthFinder software: Monte Carlo tree search (MCTS), Retro*, and a depth-first proof-number search (DFPN) algorithm, all using a template-based one-step retrosynthesis model. It is found that DFPN is inferior to both MCTS and Retro* and cannot be recommended in its current implementation. MCTS and Retro* are on a par with regard to search speed and the ability to find routes in which all starting material is in stock. However, MCTS outperforms Retro* when it comes to route quality and route diversity. MCTS more easily recovers the reference routes and tends to find a diverse set of solutions for a greater portion of the targets. We encourage practitioners and developers to benchmark their algorithms using PaRoutes and we envisage that the framework will become the community standard to compare retrosynthesis route predictions. It is available at https://github.com/MolecularAI/PaRoutes
Nanozyme Therapy in Dental Practice
Authors: Srishti Bodh  , Minakshi  , Palak Choudhary
Published: February 2022

Nanozyme Therapy in Dental Practice by Srishti Bodh, Minakshi, Palak Choudhary
Nomophobia among Students of Healthcare Colleges and Institutions: A Cross-Sectional Study
Authors: Kartik V.  , Sushil Sen  , Shivani Pandey  , Parth Tomar
Published: February 2022

INTRODUCTION: The Covid-19 pandemic has  made a student dependent on their phones as a result of which, these students were glued to their phones for various tasks. AIM: To assess the level of mobile phone dependence (nomophobia) on students of healthcare colleges and institutions in and around a South Indian city. MATERIALS AND METHOD: The study was cross-sectional in nature. Mobile phone dependence was obtained from Raines ML et al. and modified accordingly. Score obtained below 20, 20–24, and above 24 were labelled as participants not at risk, at risk, and nomophobia, respectively. Students aged 17 years or higher and  using mobile phones on a regular basis (atleast for 4 months) for at least 1–2 hours per day we included and those reporting a history of alcohol or substance abuse and any psychiatric or sleep disorder were excluded. Data was entered into SPSS version 24.0 and statistical test used were the student’s t-test and logistic regression and Pearson’s correlation keeping p value significant at ≤0.5. RESULTS: Most of the students were males (53.9%) and most students were ≥20 years in age (43.5%). 46% of the students reported using their smartphone for more than 2 hours a day and 59.9% of them reported having a poor sleep quality index of >5 (59.9%). Most of the students (40%) reported a nomophobic score of >24, With 53.2% and 51.3% females. Analysis of the logistic regression revealed a positive, linear and significant association with higher nomophobic scores and poor sleep quality index scores (r=+0.69, p=0.02 for nomophobic score >24). CONCLUSION: The present study revealed a high on nomophobia prevalence among students of healthcare colleges and institutions, which needs urgent intervention as these students are becoming addicted to smartphone usage.
A review of lactic acid bacteria isolated from marine animals: their species,
isolation site and applications
Authors: Lambuk F. , Mazlan N. , Thung T.Y. , New C.Y. , K.R. Rinai , R. Son
Published: February 2022

Marine animals are continuously exposed to a wide range of microorganisms present in
their environment. Studies indicated that the microorganisms could be found in different
parts of the animal’s body. There are different types of lactic acid bacteria in various
isolation sites and studies have disclosed the presence of Lactobacillus, Lactococcus,
Enterococcus, Streptococcus, Vagococcus, Pediococcus, Weissella, Leuconostoc, and
Carnobacterium. The lactic acid bacteria (LAB) of these animals have been the subject of
various studies. They were studied for their inhibitory activity against pathogens, tested
for their antibiotic resistance, and searched for the production of bacteriocin which some
are eventually made into commercial products. This study reviewed isolated LAB from
marine animals to discover the better potential of LAB that could be implemented in
different industries such as food and beverages, pharmaceutical, aquaculture,
nutraceutical, and medical. This review assembled the species of LAB that were isolated
from different parts of the marine animals’ bodies and their application.
Educators’ Motivation and Intention within the UTAUT Model to Adopt the Flipped Classroom: A Scoping Review
Authors: Yahaya Rusliza , Ramdan Mohamad Rohieszan , Ahmad Noor Lela , Ismail Rosmini , Khalid Khalizul , Jusoh Mohd Abdullah , Isa Rosmah Mat
Published: February 2022

There is a growing concern for educational institutions to transform and innovate their teaching and learning pedagogy to meet today's demands. This phenomenon is reflected in the rise of the flipped or inverted classroom. However, the motivation and intention of educators to transform from conventional teaching to flipped classrooms is poorly understood. Therefore, a scoping review of the literature was undertaken to identify important determinants in educators’ motivation and intention within the UTAUT model to use the flipped classroom. Databases searched included the Web of Science, Scopus, and ERIC databases. Arksey and O’Malley’s five-stage framework was utilized as the method for the scoping review process. The findings reveal four main themes and twelve sub-themes regarding educators’ motivation and intention to implement the flipped classroom, of which social factors are the most dominant determinants. By examining the crucial determinants that influence the motivation and intention of adopting flipped classrooms, this study might assist educators in successfully making the change.
Digital Marketing Workshop for SMEs in Kiaracondong During COVID-19 Pandemic
Authors: Rosimah Siti , Kamil R. Indriyati , Charisma Dinna
Published: February 2022

In the face of the COVID-19 coronavirus pandemic, the role of small and medium enterprises (SMEs) needs to be strengthened. Especially now that small and medium enterprises are no longer seen as an alternative, but as the backbone or foundation of the country's economy. There are three things that must be considered and improved in an effort to strengthen the existence of SMEs, namely finance, improving Human Resources (HR) and innovating marketing models through digital technology. MSMEs in Kiaracondong District which are engaged in culinary and handicrafts are small businesses owned and developed by individuals in the guidance, direction and supervision of the Head of the Economic and Development Section at both the sub-district and village levels. In the time of COVID-19 pandemic, the majority of MSMEs in the Kiaracondong sub-district tend to experience a decrease in sales turnover, this is because the marketing of their products is still done conventionally and only around the neighborhood where they live. Therefore, the Langlangbuana University community service team provides assistance to SMEs to develop their entrepreneurial spirit, through discussion methods and FGDs for product innovation assistance, sales promotion strategies, online marketing strategies and digital literacy. The results of the mentoring activity showed that the SME participants in the Kiaracondong sub-district actively participated in mentoring activities and could understand the strategy for developing product variations and understanding digital literacy in marketing their products through social media such as Whatsapp groups and business WhatsApp, Facebook, and Instagram.
Deteksi Penyakit Covid-19 Pada Citra X-Ray Dengan Pendekatan Convolutional Neural Network (CNN)
Authors: Harahap Mawaddah , Em Manuel Laia  , Lilis Suryani Sitanggang  , Melda Sinaga  , Daniel Franci Sihombing  , Amir Mahmud Husein
Published: February 2022

The Coronavirus (COVID-19) pandemic has resulted in the worldwide death rate continuing to increase significantly, identification using medical imaging such as X-rays and computed tomography plays an important role in helping medical personnel diagnose positive negative COVID-19 patients, several works have proven the learning approach in-depth using a Convolutional Neural Network (CNN) produces good accuracy for COVID detection based on chest X-Ray images, in this study we propose different transfer learning architectures VGG19, MobileNetV2, InceptionResNetV2 and ResNet (ResNet101V2, ResNet152V2 and ResNet50V2) to analyze their performance, testing conducted in the Google Colab work environment as a platform for creating Python-based applications and all datasets are stored on the Google Drive application, the preprocessing stages are carried out before training and testing, the datasets are grouped into theNormal and COVID folders then combined m become a set of data by dividing them into training sets of 352 images, testing 110 images and validating 88 images, then the detection results are labeled with the number 1 means COVID and the number 0 for NORMAL. Based on the test results, the ResNet50V2 model has a better accuracy rate than other models with an accuracy level of about 0.95 (95%) Precision 0.96, Recall 0.973, F1-Score 0.966, and Support of 74, then InceptionResNetV2, VGG19, and MobileNetV2, so that ResNet50V2-based CNNs can be used as initial identification for the classification of a patientinfected with COVID or NORMAL.
Feature Expansion Word2Vec for Sentiment Analysis of Public Policy in Twitter
Authors: Alvi Rahmy Royyan  , Erwin Budi Setiawan
Published: February 2022

Social media users, especially on Twitter, can freely express opinions or other information in the form of tweets about anything, including responding to a public policy. In a written tweet, there is a limit of 280 characters per tweet and this allows for problems such as vocabulary mismatches. Therefore, in this study, the feature expansion Word2vec method was applied to overcome when the vocabulary mismatches occur. This study develops and compares the Twitter sentiment analysis system using the feature expansion Word2vec method with the Logistic Regression (LR) and Support Vector Machine (SVM) classification algorithms and the system without the feature expansion Word2Vec method. The results of this study, the feature expansion Word2Vec method on the SVM classification algorithm succeeded in increasing the system accuracy up to 0,99% with an accuracy value of 78,99%.
Optimization Prediction of Big Five Personality in Twitter Users
Authors: Gita Safitri  , Erwin Budi Setiawan
Published: February 2022

Various kinds of information can be acquired from social media platforms; one of them is on Twitter. User biographical information and tweets are the essential assets for research that can describe the Big Five Personality, including openness, conscientiousness, extraversion, agreeableness, and neuroticism. Several previous studies have tried the prediction of Big Five Personality. However, the authors found problems in how to optimize the work of the personality prediction system. So, in this study, Big Five Personality predictions were carried out on users of Twitter and improved the performance of the personality prediction system. We implement optimization techniques such as sampling, feature selection, and hyperparameter tuning to enhance the performance. This study also applies linguistic feature extraction, such as LIWC and TF-IDF. By using 287 Twitter users that have permitted their data to be crawled acquired from an online survey using Big Five Inventory (BFI), and applying all optimization techniques, the average accuracy result is 84.22% which is a 74.44% gain over the specified baseline.
Speaker Identification Using a Convolutional Neural Network
Authors: Dwijayanti Suci , Putri Alvio Yunita , Suprapto Bhakti Yudho
Published: February 2022

Speech, a mode of communication between humans and machines, has various applications, including biometric systems for identifying people have access to secure systems. Feature extraction is an important factor in speech recognition with high accuracy. Therefore, we implemented a spectrogram, which is a pictorial representation of speech in terms of raw features, to identify speakers. These features were inputted into a convolutional neural network (CNN), and a CNN-visual geometry group (CNN-VGG) architecture was used to recognize the speakers. We used 780 primary data from 78 speakers, and each speaker uttered a number in Bahasa Indonesia. The proposed architecture, CNN-VGG-f, has a learning rate of 0.001, batch size of 256, and epoch of 100. The results indicate that this architecture can generate a suitable model for speaker identification. A spectrogram was used to determine the best features for identifying the speakers. The proposed method exhibited an accuracy of 98.78%, which is significantly higher than the accuracies of the method involving Mel-frequency cepstral coefficients (MFCCs; 34.62%) and the combination of MFCCs and deltas (26.92%). Overall, CNN-VGG-f with the spectrogram can identify 77 speakers from the samples, validating the usefulness of the combination of spectrograms and CNN in speech recognition applications.
The Role of Service and Product Quality on Customer Loyalty
Authors: Taufik Agus , Santoso Sugeng , Fahmi Muhamad Irfan , Restuanto Faqih , Yamin Steven
Published: February 2022

Coffee shops are today's businesses with good and competitive prospects in providing customer satisfaction and building customer loyalty. This study aims to analyze the relationship between service quality and product quality on customer satisfaction and loyalty, the relationship between customer satisfaction and customer loyalty, and the relationship between product and service quality and customer loyalty mediated by customer satisfaction. The study was conducted using quantitative methods, sampling a questionnaire to 100 customers of Coffee Shop. The study was conducted in August 2021. Meanwhile, to analyze the relationship between variables, using partial least squares (PLS). Based on the study results, it can be concluded that service quality directly affects customers, especially customer satisfaction. Product quality also affects customer satisfaction and loyalty and vice versa. However, service quality did not directly affect customer loyalty. Meanwhile, mediation through customer satisfaction and product quality indirectly affects customer loyalty.
O estabelecimento da psiquiatria infantil em Minas Gerais: tratar e educar
Authors: Sampaio Carlos Eduardo Resende , UFMG Adriana Araújo Pereira Borges -
Published: February 2022

Carlos Eduardo Resende Sampaio
Primeiro Autor
Mestrando em Educação pela Universidade Federal de Minas Gerais
carlosresendesapaio@gmail.com

Adriana Araújo Pereira Borges
Professora Adjunta da Univers
O posicionamento dos estados brasileiros frente às possibilidades de flexibilização curricular proposta para o novo ensino médio: primeiras reflexões
Authors: Amorim Rebeca , Ferri Cássia
Published: February 2022

Vivemos um momento histórico marcado por reformas fundamentadas em uma agenda globalmente estruturada. Dar nova forma ao texto que normatiza uma política pública cria possibilidade de expressar convenientemente os ideais de quem detém o poder. O Brasil tem justificado a necessidade de reformas pela busca da chamada "qualidade educacional" o que o leva a comparar-se com outros países. No âmbito da educação, políticas que já se mostraram ineficientes nos Estados Unidos, por exemplo, estão sendo consolidadas em nosso país. Apesar da evasão escolar e da deficiência do processo de formação dos professores serem apontados como causas do fracasso da educação pública, a novidade legal, apresentada pelo texto da “reforma do ensino médio”, possibilita aos estados firmarem parcerias e apresentarem soluções privadas para os problemas públicos. A atual reforma do ensino médio consolidada a partir da aprovação da Lei 13.415/ 2017 torna ainda mais evidente este contexto. Na proposta, formação geral básica e itinerários formativos dividem o espaço/tempo de formação no “novo ensino médio” e a flexibilização curricular prevê que, pelo menos um dos itinerários, o técnico-profissional, poderá ser realizado em regime de colaboração e em parceria com outras instituições, possibilitando assim como já recorrente em outros países a privatização de boa parte do sistema educacional. Entretanto, é salientada a liberdade de organização. Nos últimos anos, os estados brasileiros têm se desdobrado para dar conta da “tarefa de casa”: interpretar a organização curricular aprovada pela Reforma. Apesar do órgão ministerial responsável pelas questões educacionais, este processo tem sido definido pela força-trabalho do Conselho Nacional de Secretários de Educação, marcando acentuada presença nas decisões desta reforma desde a elaboração da controversa terceira versão da Base Nacional Comum Curricular. A partir de 2019 este Conselho, associação de direito privado, formula a agenda de aprendizagem “Frente de Currículo e Novo Ensino Médio”, reunindo temas considerados prioritários para estados e municípios, elaborada em regime de colaboração entre organizações governamentais e iniciativa privada. A partir deste contexto, o estudo que levamos a efeito questiona o posicionamento político assumido pelos estados, por meio das secretarias de educação, nos documentos dos currículos dos territórios em relação a organização curricular prescrita para os itinerários formativos a partir das normativas da reforma do ensino médio. Esta pesquisa, apoiada na metodologia de análise relacional e ciclo de políticas públicas educacionais, busca analisar como os Estados, no uso de sua autonomia constitucional, atuam em seus documentos curriculares territoriais, a partir do contexto de influência da reforma do ensino médio.