bluuebunny/crossref_metadata_2025 huggingface dataset:
SISTEM MANAJEMEN MUTU ISO 21001: 2018 SEBAGAI STRATEGI PENINGKATAN KUALITAS PENDIDIKAN DI ERA REVOLUSI INDUSTRI 4.0
Authors: Kusumawati Niluh Ari
Published: January 2024

Peran pendidikan dalam era revolusi industri 4.0 menjadi semakin penting. Pendidikan harus mampu mempersiapkan generasi muda untuk dapat beradaptasi dengan cepat terhadap perkembangan teknologi dan juga mampu menghasilkan sumber daya manusia yang kreatif, inovatif, dan mampu berpikir kritis. Di era revolusi industri 4.0, manajemen mutu ISO 21001: 2018 menjadi semakin penting karena teknologi dan digitalisasi semakin mempengaruhi cara belajar dan mengajar. Pendidikan dan pelatihan tidak lagi terbatas pada kelas fisik, tetapi juga dapat dilakukan secara online dan jarak jauh. Di era revolusi industri 4.0, organisasi yang ingin bertahan di pasar global harus memperbaiki manajemen mutu mereka. Penggunaan manajemen mutu internasional ISO 21001: 2018 adalah pilihan yang tepat, karena membantu memastikan organisasi beroperasi sesuai standar internasional dan memberikan manfaat besar bagi organisasi. Dengan manajemen mutu ISO 21001: 2018, organisasi pendidikan dan pelatihan dapat memastikan bahwa mereka tetap relevan di era revolusi industri 4.0 dan memberikan layanan yang berkualitas kepada pelanggan. Dalam menerapkan ISO 2100: 2018, organisasi pendidikan perlu memperhatikan kecepatan dan fleksibilitas dalam merespons perubahan, serta membangun budaya inovasi yang kuat di dalam organisasi. Selain itu, penerapan ISO 21001: 2018   di era revolusi industri 4.0 juga memerlukan integrasi yang lebih baik antara sistem manajemen mutu dengan teknologi digital.
PENERAPAN METODE PEMBELAJARAN SELF ORGANIZED LEARNING ENVIRONMENT DALAM MENGEMBANGKAN SOFT SKILL MAHASISWA
Authors: Ketut Nurhayanti , Astri Pramitari I Gusti Ayu , Suwintana I Ketut , Budiada I Made
Published: January 2024

This research examines the application of the self-organized learning environment learning method in an effort to develop the soft skills of students in the Applied Managerial Accounting Undergraduate Study Program at the Bali State Polytechnic. This research method is descriptive qualitative using interview and questionnaire data collection techniques for 96 respondents. The result is a self-organized learning environment learning method that combines internet technology as a reference source for students with lecturers as a reference source that can develop students' soft skills such as having an initiative, independent, trustworthy and communication skills.
Cuando el valor ilocutivo no coincide con el locutivo: Estrategias para fomentar la comprensión en L2
Authors: Laurencio Tacoronte Ariel
Published: January 2024

Algunas estructuras gramaticales, como ESTAR + GERUNDIO en español y BE + ING en inglés, centro de este estudio, implementan un desajuste convencionalizado entre valor locutivo e ilocutivo. Esto significa que lo enunciado por medio de tales estructuras no es exactamente a lo que apunta la intención comunicativa del enunciador. O sea, lo que se quiere decir a través de ellas no coincide con lo que en sí se dice, por lo que se hace necesario inferirlo. Estas inferencias de algo muchas veces no explicitado en el mismo texto plantean serias dificultades de comprensión, por ejemplo en la lectura en una lengua extranjera (o L2). Proponemos aquí un modelo teórico que nos permite conceptualizar el funcionamiento de estas estructuras, así como desarrollar a partir de ello estrategias para promover la debida identificación de las inferencias promovidas por estos operadores gramaticales.
Ensuring effective insolvency procedures of natural persons (entrepreneurs): analysis of the legal regulation of insolvency in the European Union and Ukraine
Authors:   Mykolas Romeris University, Lithuania, Andrieieva Anhelina
Published: January 2024

"Full discharge of debts, as an outcome of the insolvency proceeding, should enable an entrepreneur to pursue their economic activity onward. This research analyses the implementation of the European Union’s discharge of debt standards into Ukrainian legislation. The article focuses on the comparison of the discharge procedures of natural persons (entrepreneurs) between the Code of Ukraine on Bankruptcy Procedures (CUBP) No. 2597-VIII from 18 October 2018 and the Directive (EU) 2019/1023 on restructuring and insolvency from 20 June 2019. As a result, the author observes that the CUBP maintains a different approach to protecting creditors’ and debtors’ interests in the discharge procedures compared to the Directive (EU) 2019/1023 on restructuring and insolvency. In conclusion, the author proposes approximating Ukrainian legislation to European standards by amending the CUBP. Keywords: discharge of debts, EU law, insolvency proceedings of entrepreneurs, repayment plan."
Conditionality in extreme circumstances: the IMF and emergency financing during the COVID-19 pandemic
Authors:   Rīga Stradiņš University, Latvia, Baumane Mara , Bukovskis Karlis
Published: January 2024

The article highlights the shift in lending policy towards instruments without ex post conditionality by the International Monetary Fund (IMF) amid the COVID-19 pandemic in 2020. The objectives of the article are two-fold: Firstly, it aims to clearly indicate the shift of IMF lending policy towards instruments without conditionality in 2020; secondly, it complements the existing academic literature on changes in conditionality by testing three factors that contribute to the shift. It is concluded that similarly to the global financial crisis in 2008, more discretion was given to IMF staff to rapidly respond to the crisis and that the IMF staff increased the Fund’s power position in the global financial safety net through expanded lending. A novelty around the COVID-19 crisis is the change in the normative debate around conditionality, which intensified in the years before the pandemic, suggesting that a more permanent change in IMF conditionality policy is taking shape. Keywords: Conditionality, COVID-19, Emergency Financing, International Monetary Fund.
State compensation to the victim in criminal proceedings is an integral component of the just resolution of criminal legal matters
Authors:   EKA University of Applied Sciences, Latvia, Saukane Larisa
Published: January 2024

"In recent years, there has been attention, both at the international and national levels, on the protection of the rights of victims of criminal offences. The first article of the Criminal Procedure Law outlines the objective of criminal proceedings, namely, to establish a procedural order that ensures the effective application of Criminal Law norms and the fair regulation of criminal legal relations without unjustified interference in a person’s life. One of the key elements of this fair regulation of legal relations is recognising the victim’s right to compensation for the harm suffered. A person who has been a victim of a criminal offence has the right to state compensation, as well as the right to seek compensation within the framework of criminal proceedings, which will be collected from the guilty party. It should be noted that legislative acts provide the opportunity for the victim to both receive state compensation and demand it from the guilty party. Keywords: State compensation, Victim, Criminal proceedings."
Função sexual em mulheres com ovários policísticos que utilizam anticoncepcionais orais
Authors: Bento Luana Schaefer , Nunes Gleice Mara Alves , Furuya Júlia , Fagionato Júlia Watanabe , Both Mariana de Andrade , Ie Luis Bin Ro
Published: January 2024

Objetivo: Investigar os efeitos da SOP na qualidade de vida das mulheres em relação a função sexual de portadoras de SOP que fazem uso de anticoncepcional oral. Métodos: Trata-se de um estudo epidemiológico do tipo observacional de coorte retrospectivo, conduzido em ambiente virtual com 50 mulheres portadoras de SOP que utilizam anticoncepcionais orais. Foram investigadas quanto à sua função sexual através do Índice de Função Sexual Feminina (FSFI). Dados obtidos foram analisados por estatística descritiva com auxílio do software. O estudo foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: Das 102 respostas obtidas somente 45 utilizavam anticoncepcionais orais há mais de 3 meses e possuíam SOP. Dessas, 20 utilizavam anticoncepcionais orais com concentração de etinilestradiol maior ou igual a 0,035mg. Mulheres que apresentam SOP e utilizam anticoncepcionais com essa concentração obtiveram maiores escores de FSFI do que aquelas que utilizam anticoncepcionais com concentrações menores. O risco relativo da exposição a concentrações maiores que 0,035mg foi de 0,75. Conclusão: Conclui-se que os anticoncepcionais orais afetam a função sexual das pacientes de diferentes maneiras e a SOP é um fator que agrava essa situação. Sugere-se o aprofundamento das investigações sobre o tema estudado.
Reinforcement materials for polymethyl methacrylate used in denture base: a bibliometric analysis
Authors: Neves Bruna Rocha , Costa Rayanna Thayse Florêncio , Freitas Rodrigo Falcão Carvalho Porto de , Leão Rafaella Souza , Cintho Osvaldo Mitsuyuki , Carreiro Adriana da Fonte Porto , Moraes Sandra Lúcia Dantas
Published: January 2024

Objective: Synthesize the scientific production and the evolution of the materials available for the reinforcement of polymethyl methacrylate used in denture bases. Methods: The search was conducted on the Web of Science database in august 2023, and a bibliometric mapping in the VOSviewer software program was used. Data included from the included articles were title and abstract terms, type of document, number of citations, journal of publication, most cited articles and year of publication were selected for analysis. The variables, corresponding authors country, particle type and size, properties, study type and results were manually included. Results: A total of 410 were selected for analysis. The most productive years were found between 2016 and 2022. 375 in vitro studies (91.46%) and 371 articles testing inorganic particles (90.48%). Most of the properties evaluated were mechanical, 198 studies used nanometer-sized particles (48.29%), followed by 12 studies on micrometer sizes (2.92%). Final considerations: Global increase in the last seven years of research on PMMA reinforcements, especially in vitro studies with inorganic and nano-sized materials demonstrates there is a need to improve PMMA with better mechanical and antimicrobial properties for application as a denture base.
Avaliação do estado de maturação e desempenho esportivo de escolares
Authors: Brito Felipe Machado , Ferreira Cirley Pinheiro , Silvino Valmir Oliveira , Moura Rayane Carvalho de , Veras João Victor Neves , Sousa Bruna Lorena Soares Cavalcante , Santos Marcos Antonio Pereira dos
Published: January 2024

Objetivo: Analisar a influência da maturação sobre o desempenho esportivo em atletas de idade escolar. Métodos: Estudo transversal com 26 atletas de Handebol (12,4 ± 0,85 anos, 156,9 ± 8,07 cm, 157,93 ± 7,11 kg), sendo 46,1% do sexo feminino. Foram realizados testes físicos e antropométricos. A maturação foi avaliada pela fórmula de estimativa do Pico de Velocidade do Crescimento (PVC). Analisada a correlação de Pearson para verificar a influência da idade no PVC e testes físicos. O nível de significância foi estabelecido em p<0,05. Resultados: Atletas do sexo feminino apresentaram correlação moderada positiva com os testes de abdominal, salto contra-movimento e consumo máximo de oxigênio (r =0,633, p =0,027; r =0,694, p =0,012; r =0,582, p =0,047, respectivamente), e forte negativa para os testes de arremesso, dinamometria da mão dominante e agilidade (r =-0,792, p =0,002; r =-0,818, p =0,001; r =-0,720, p =0,008, respectivamente) para idade no PVC. Entre os atletas do sexo masculino não foram verificadas correlações significativas da idade no PVC e testes físicos. Conclusão: A idade no PVC pode influenciar no desempenho físico de atletas, em especial do sexo feminino.
Potencial terapêutico dos canabinoides em doenças neurodegenerativas: Parkinson, Alzheimer e Esclerose Múltipla
Authors: Santos Brenda Winona dos , Fernandes Idonilton da Conceição , Dias Josiane de Fatima Gaspari , Montrucchio Deise Prehs , Dalarmi Luciane , Miguel Odbulio Gomes , Miguel Marilis Dallarmi
Published: January 2024

Objetivo: Analisar sobre os efeitos dos canabinoides no tratamento e/ou alívio de sintomas de doenças neurodegenerativas, como: Parkinson, Doença de Alzheimer e Esclerose Múltipla. Métodos: Foi realizada uma revisão integrativa intencionando compilar os principais resultados do uso dos canabinoides na prevenção e controle de doenças neurodegenerativas com foco nas doenças de Parkinson, Alzheimer e Esclerose Múltipla. Foram selecionados artigos científicos disponíveis no portal Periódicos Capes distribuídos nas bases de dados PubMed, Science Direct e Medline. Resultados: Foram encontrados 331 artigos científicos filtrados apenas para testes clínicos, destes após triagem foram lidos integralmente 52 textos e para esta revisão foram selecionados 21 artigos. Os artigos selecionados demonstram resultados positivos na melhora de sintomas e na qualidade de vida geral em todas as patologias. A maioria dos estudos foram realizados em países europeus, demonstrando a necessidade de maiores investimentos em pesquisas clínicas com canabinoides principalmente na América do Sul. Considerações finais: Com a análise dos textos é possível concluir que os canabinoides Tetra-hidrocanabinol (THC) e Canabidiol (CBD) são compostos benéficos em testes clínicos com resultados positivos no controle e prevenção de sintomas das três doenças neurodegenerativas escolhidas para esta revisão.
VARIATION IN THERMAL STRESS BEHAVIOUR OF COMPOSITE MATERIALS BY THERMOMECHANICAL TECHNIQUE (TMA)
Authors: Khalaf Rafid H. , Abd-Alghafour Nabeel M. , Abdulrahman Ahmed F.
Published: January 2024

In this study, a polymeric-based composite material was made using 80% epoxy polyester 20% and unsaturated polyester resin. The polymeric composites were prepared by manual moulding method by adding a support material of silica powder to the mixture by weight (0%, 5%, 10%, and 15%) to examine one of the thermal properties which are thermal expansion. A comparison was made with the polymeric mixture before and after the reinforcement. The results of the study showed that the coefficient of thermal expansion increases with increasing temperatures, while it decreases at high temperatures. The results also showed that there is a decrease in the degree of glass transition with an increase in the concentration of the additive, and it was also noted that an increase in the percentage of silica at 15% decreases the value of the thermal expansion coefficient compared to other samples.
Pathogenesis, angiogenesis of diabetic macular edema and general characteristics of its treatment (Literature review. Part 1)
Authors:   Chita State Medical Academy, Chita, Russia, Taskina E.S. , Logunov N.A. ,   Chita State Medical Academy, Chita, Russia, Kharintseva S.V. ,   Chita State Medical Academy, Chita, Russia, Makarchuk N.A. ,   Chita State Medical Academy, Chita, Russia
Published: January 2024

Currently, the increase in the prevalence of diabetes mellitus is in the nature of a pandemic. Diabetic macular edema is a vision-threatening complication of diabetic retinopathy, the pathogenesis of which is multifactorial and includes hyperglycemia, endothelial dysfunction, leukostasis and inflammation, vasoconstriction and occlusion, oxidative stress and ischemia, neovascularization, which leads to the accumulation of exudative fluid, thickening of the central zone of the retina and irreversible processes of photoreceptors neurodegeneration with a significant decrease in visual functions. The article presents up-to-date information on the epidemiology, patho- and angiogenesis of this condition as well as the general characteristics of the DMO therapy. It consists of primary treatment of diabetes, laser photocoagulation and anti-angiogenic therapy. Intravitreal drug therapy based on VEGF inhibitors is currently the standard first-line treatment for DMO. The authors emphasize the necessity for further study of trigger points in the pathogenesis of diabetic retinopathy and the development of diabetic macular edema in order to find new drugs and work out a more individualized approach to patients. Key words:: diabetic retinopathy, diabetic macular edema, vascular endothelial growth factor, VEGF-therapy
Ocular dirofilariasis mimicking orbital tumors: A case report
Authors:   Russian Center for Eye and Plastic Surgery, Ufa, Russia, Khuramshina D.Z. , Orenburkina O.I. ,   Russian Center for Eye and Plastic Surgery, Ufa, Russia, Bakiev R.R. ,   Russian Center for Eye and Plastic Surgery, Ufa, Russia, Babushkin A.E. ,   Russian Center for Eye and Plastic Surgery, Ufa, Russia
Published: January 2024

Dirofilariasis (from Latin «ominous thread») is transmissible facultative zoonotic biohelminothosis, caused by thread-like helminth from nematodes of the genus Dirofilaria. Two species are spread throughout Russia – D. repens and D. immitis. Dirofilariasis prevalence increase and expansion of the prevalence area cause ophthalmologists to raise concern over it. The article presents a clinical case report of a female patient, 71, with dirofilariasis masquerading as orbital tumors. The patient underwent transcutaneous orbitotomy and ‘tumor’ resection. The subsequent pathoanatomical examination of the resected conglomerate revealed the presence of helminth, whose fragments were later identified as D. repens in the laboratory of sanitary and epidemiological station. Abnormal clinical picture of dirofilariasis, and its ocular capsular form in particular, determines that the rare disease often mimics various non-parasitic disorders. This circumstance can hinder the diagnosis and delay proper treatment, so it is necessary to raise clinicians’ awareness and alertness about this ocular pathology. Key words:: dirofilariasis, orbital tumors, surgical treatment, Dirofilaria repens
Results of implantation of a monofocal intraocular lens Clareon with an automated delivery system Autonome (one year of observation)
Authors:   Medical University Reaviz, Samara, Russia, Stebnev V.S. ,   Ophthalmic clinic Eye Surger y, Samara, Russia, Stebnev S.D. ,   Medical University Reaviz, Samara, Russia,   Ophthalmic clinic Eye Surger y, Samara, Russia, Malov I.V. ,   Medical University Reaviz, Samara, Russia,   Ophthalmic clinic Eye Surger y, Samara, Russia, Skladchikova N.I. ,   Ophthalmic clinic Eye Surger y, Samara, Russia, Vashchenko T.Y. ,   Ophthalmic clinic Eye Surger y, Samara, Russia
Published: January 2024

Material and methods. The short- and long-term results of phacoemulsification with implantation of 700 Clareon intraocular lenses (IOL) preloaded into disposable pneumatic AutonoMe delivery systems were studied. The optical power of the IOL was calculated using the Verion system using modern formulas for emmetropia. Functional and refractive results, surgical and postoperative complications were assessed. Results. Of the 700 Clareon IOL implantations performed, 693 (99.0%) were without complications; complications occurred in 7 (1.0%) eyes. By 12 months of observation, BCDVA and UCDVA increased from 0.15±0.03 to 0.65±0.09 and from 0.31±0.04 to 0.76±0.12 (p<0.05), respectively. Refraction of the target was achieved in 90% of patients. The loss of endothelial cells from the baseline level was 4.8%. In all patients, the optical part of the IOL remained stably transparent, no glistening phenomena were observed in any case; the haptic component of the IOL provided a stable correct central position of the IOL in the capsule bag. Secondary cataract developed in 22/605 (3.6%) eyes, which required dissection in 19/605 (3.1%) eyes. Conclusion. The new monofocal intraocular lens Clareon is high-tech and can be widely used in clinical practice. The new automated pneumatic delivery system AutonoMe is efficient and safe. Key words: phacoemulsification, Clareon, automatic IOL delivery system, glistening, secondary cataract
MAIN ANOMALIES OF HYSTERESIS PROPERTIES OF DISPERSE ALLOYS OF HIGHLY ANISOTROPIC MAGNETS BASED ON RARE EARTH METALS
Authors: Манаков Н.А. , Ерёмин А.М.
Published: January 2024

Проведено обобщение основных аномалий гистерезисных свойств дисперсных сплавов высокоанизотропных магнетиков по результатам ранее проведенных экспериментальных и теоретических исследований. К этим аномалиям сплавов типа SmСo5 и Nd2Fe14B полученных из паровой фазы или сверхбыстрой закалки из жидкого состояния относятся: метастабильное состояние после термического размагничивания и ярко эффект термического намагничивания микрокристаллических сплавов, образование доменов обменного взаимодействия и микромагнитный характер процесса перемагничивания нанокристаллических сплавов, а также перемагничивание субмикрокристаллических сплавов путем неоднородного вращения намагниченности кристаллитов.

A generalization of the main anomalies of the hysteresis properties of dispersed alloys of highly anisotropic magnets has been carried out based on the results of previously conducted experimental and theoretical studies. These anomalies of alloys such as SmСo5 and Nd2Fe14B obtained from the vapor phase or ultra-fast quenching from the liquid state include: a metastable state after thermal demagnetization and the pronounced effect of thermal magnetization of microcrystalline alloys, the formation of exchange interaction domains and the micromagnetic nature of the magnetization reversal process of nanocrystalline alloys, as well as the magnetization reversal of submicrocrystalline alloys by inhomogeneous rotation of the magnetization of crystallites.
MODELING THE INTERACTION BETWEEN THE SURFACE OF MULTI-ELECTRODE SENSORS WITH DIFFERENT GEOMETRY OF SENSITIVE ELECTRODE SHAPES IN THE ELECTRIC FIELD
Authors: Колмогорова С.С.
Published: January 2024

Для обеспечения безопасной и стабильной работы любой энергосистемы, необходимо постоянно контролировать и обслуживать оборудование и линии электропередач, находящиеся под напряжением. В зависимости от условий эксплуатации, необходимо анализировать электрические поля, которые не всегда являются однородными. Для анализа распределения заряда на сенсорные элементы заряда различной формы при воздействия электрического поля в статье представлена имитационная модель. Беря в расчет пространственное распределение электрического поля, неоднородность исследуемого поля, и накопление поверхностного заряда на датчик была получена количественная связь измеряемого электрическим полем и конечными результатами измерения. Результаты моделирования показывают высокую точность при оценке взаимосвязи между составляющими электрического поля для различных форм сенсорных элементов и хорошо согласуются с результатами анализа, полученными методом конечных элементов.

To provide safe and stable operation of any power system, it is necessary to constantly monitor and maintain energized equipment and transmission lines. Depending on the operating conditions, it is necessary to analyze electric fields, which are not always homogeneous. In order to analyze the charge distribution on differently shaped sensing elements under the influence of electric field, a simulation model is presented in this paper. By taking into account the spatial distribution of the electric field, the inhomogeneity of the field under study, and the accumulation of surface charge on the sensor, a quantitative relationship between the measured electric field and the final measurement results was obtained. The simulation results show high accuracy in evaluating the relationship between the electric field components for different forms of sensor elements and agree well with the analysis results obtained by finite element method.
INVESTIGATION OF THE EFFECT OF FILTERS ON IMAGES OBTAINED BY IMPLEMENTING THE METHOD OF ACTIVE FORMATION OF SPECTRAL IMAGES USING A HYPERSPECTRAL CUBE
Authors: Шубин А.К.
Published: January 2024

В работе рассмотрены известные на данный момент фильтры изображений, относящиеся к разным классам для выявления особенностей при устранении шума с изображений, полученных с помощью метода активного формирования спектральных изображений с помощью гиперспектральных данных. Для этого были применены низкочастотный, высокочастотный, Гауссов, медианный, средний, нерезкий, консервативный, Лапласовский, удаление пятен Кримминса, двусторонний и плоский фильтры на изображения, полученные на одной длине волны лазерного излучения, одного вещества, но различных подложках, для выбора оптимального фильтра, в случаях сохранения полезного сигнала, эффективности фильтрации при различных подложках и удаления шума и выделения вещества на изображении. Так же были получены амплитудно-частотные характеристики полученных изображений после фильтрации для получения критериев выбора оптимального фильтра.

The paper considers currently known image filters belonging to different classes to identify features when eliminating noise from images obtained using the method of active spectral image formation using hyperspectral data. For this purpose, low-frequency, high-frequency, Gaussian, median, medium, blurred, conservative, Laplace, Crimmins stain removal, two-sided and flat filters were applied to images obtained at the same wavelength of laser radiation, of the same substance, but on different substrates, to select the optimal filter, in cases of preservation of a useful signal, filtration efficiency at various substrates and the removal of noise and the release of matter in the image. The amplitude-frequency characteristics of the images obtained after filtering were also obtained to obtain criteria for choosing the optimal filter.
REVIEW: INDUSTRIAL EXPLOSIVES. HISTORY OF CREATION, PROPERTIES, COMPONENTS.
Authors: Попов В.О. , Комов В.Н.
Published: January 2024

Взрывчатые вещества как высококонцентрированный и экономичный источник энергии широко используется в различных отраслях народного хозяйства. Массовые взрывы широко используются при вскрытии рудных тел, угольных пластов и месторождений других полезных ископаемых, строительстве, при сооружении плотин и насыпей и др. В настоящее время сложно представить функционирование различных отраслей промышленности без использования энергии взрыва. Данная статья посвящена литературному обзору промышленных взрывчатых веществ. Рассмотрены основные соединения, применяемые при компоновке тех или иных видов ВВ, будь то сухие механические смеси, водонаполненные взрывчатые вещества или эмульсионные составы.

This article is devoted to a literature review of industrial explosives used previously and currently used. The main compounds used in the assembly of certain types of explosives, be they dry mechanical mixtures, water-filled explosives or emulsion compositions, are listed.
synthesis and properties of 1-methyl-5-prop-2-ynyloxy-1H-[1,2,4]triazole
Authors: Пивоварова Е.В. , Крупнова И.А. , Босов К.К. , Суханов Г.Т. , Суханова А.Г. , Филиппова Ю.В.
Published: January 2024

Реакцией нуклеофильного гетероциклического замещения (SNipso-замещения) нитрогруппы в молекуле субстрата – 1-метил-5-нитро-1,2,4-триазола с участием пропаргилового спирта, как О-нуклеофильного агента, синтезировано новое функционализированное триазоловое производное – 1-метил-5-проп-2-инилокси-1Н-[1,2,4]триазол. Найдены условия взаимодействия 1-метил-5-нитро-1,2,4-триазола с пропаргиловым спиртом, обеспечивающие конверсию субстрата более 98 %. Доля продуктов конкурентных реакций – 1-метил-1,2,4-триазол-5-она и N-С триазолилтриазолона составляет 7,5 % и 0,9 % соответственно. Структура полученного алкинового производного надежно подтверждена комплексным анализом с помощью спектроскопического метода ЯМР: протонного магнитного резонанса (1Н ЯМР-спектроскопия) и спектроскопии ЯМР на ядрах углерода (13С ЯМР-спектроскопия). Методом ДСК изучены термические характеристики. Благодаря наличию функциональной алкиновой группы полученное соединение представляет интерес для использования его в качестве диполярофила в реакциях 1,3-диполярного циклоприсоединения, так как это позволит аккумулировать в одной молекулярной структуре полезные свойства как симметричного 1,2,4-триазола, так и образующегося в ходе реакции вицинального 1,2,3-триазола.

A new functionalized triazole derivative, 1-methyl-5-prop-2-ynyloxy-1Н-[1,2,4]triazole, was synthesized by the reaction of nucleophilic substitution (SNipso-substitution) of the nitro group in the molecule of substrate 1-methyl-5-nitro-1,2,4-triazole, involving propargyl alcohol as an О-nucleophilic agent. The interaction conditions between 1-methyl-5-nitro-1,2,4-triazole and propargyl alcohol, which ensure a substrate conversion of more than 98%, were found. The proportions of the competitive reaction products, 1-methyl-1,2,4-triazol-5-one and an N-С bicycle, were 7,5 and 0,9%, respectively. The structure of the resultant alkyne derivative was credibly confirmed by a combined analysis using NMR spectroscopy, such as proton magnetic resonance (1Н NMR spectroscopy) and NMR spectroscopy on carbon nuclei (13С NMR spectroscopy).The thermal behavior was characterized by the DSC technique. Because of the presence of the functional alkyne group, the resultant compound is appealing for use as a dipolarophile in 1,3-dipolar cycloaddition reactions, as this will allow a single molecular structure to accumulate useful properties of both symmetric 1,2,4-triazole and vicinal 1,2,3-triazole resulting from the reaction.
FEATURES OF THE PERFORMANCE OF BORON-CONTAINING EXPLOSIVE COMPOSITIONS
Authors: Карлина Е.В. , Халдеев Е.В. , Батьков М.Ю. , Гришина С.Е. , Шкуряков А.В. , Крутиков П.А.
Published: January 2024

В настоящее время бор рассматривается в качестве перспективного компонента взрывчатых составов благодаря высокой теплоте сгорания, что может значительно повысить фугасность взрывчатых веществ по сравнению с обычно используемыми добавками алюминия. Однако существуют противоречивые данные относительно эффективности применения бора. В работе проведены исследования по определению условий, позволяющих реализовать положительный эффект от замены алюминия на бор во взрывчатых составах с целью повышения их фугасности. В результате проведенных исследований определены особенности работоспособности боросодержащих взрывчатых составов. Показано, что необходимо соблюдать определенный баланс между массовым содержанием взрывчатого компонента и бора, при котором наблюдается значительное повышение фугасности.

Currently, boron is considered as a promising component of explosive compositions due to its high combustion heat, which can significantly increase blasting power of explosives compared to commonly used aluminum additives. However, there are conflicting data regarding the efficiency of the boron use. In this work, the studies were carried out to determine the conditions that make it possible to realize the positive effect of replacing aluminum with boron in explosive compositions in order to increase their blasting power. As a result of the implemented research, the features of the performance of boron-containing explosive compositions were determined. It was shown that it is necessary to maintain a certain balance between the mass content of an explosive component and boron, wherein a significant increase in blasting power is observed.
HIGH INTENSITY PULSED IONIZING RADIATION DOSE RATE MONITORING SYSTEM BASED ON MICROWAVE DIAGNOSTICS
Authors: Морозов Н.Н. , Нурмагомедов Т.Н. , Каторжин И.С.
Published: January 2024

В статье рассмотрены вопросы контроля процессов импульсной дозиметрии интенсивных излучений. Измерения осуществляются высокочастотными методами диагностики плазменного образования, возникающего в газе при его облучении интенсивным импульсом радиации. Описаны физические принципы функционирования системы регистрации на основе применения СВЧ-диагностики. Приведена схема измерительного тракта с применением компактного полоскового волновода. Описана конструкция волнового цилиндрического преобразователя. Приведены граничные условия применимости предложенной системы регистрации ионизирующего излучения.

The article discusses the issues of monitoring the processes of pulse dosimetry of intense radiation. Measurements are carried out by high-frequency methods of diagnostics of plasma formation occurring in a gas when it is irradiated with an intense pulse of radiation. The physical principles of the registration system functioning based on the use of microwave diagnostics are described. The scheme of the measuring path with the use of a compact strip waveguide is given. The design of a cylindrical wave converter is described. The boundary conditions of applicability of the proposed ionizing radiation detection system are given.
DESIGN OF AN UV CHAMBER FOR STUDYING THE DESTRUCTION OF POLYMER COMPOSITE MATERIALS
Authors: Лукачевская И.Г. , Васильева Е.Д. , Иванов А.Н. , Кычкин А.А.
Published: January 2024

Статья представляет собой обзор, в котором рассматривается проблема нехватки научной основы для прогнозирования долговечности полимерных композиционных материалов (ПКМ) при длительной эксплуатации. Особое внимание уделяется влиянию ультрафиолетового (УФ) излучения и механических нагрузок на деструкцию ПКМ. Текст содержит результаты исследований, связанных с деградацией полимеров под воздействием УФ-излучения, влиянием УФ-облучения на механические свойства полимерных композитов с углеродным волокном, а также механизмами пожелтения тонких пленок эпоксидных и винилэфирных смол.

The article is a review that addresses the problem of insufficient scientific basis for predicting the durability of polymer composite materials (PCM) during long-term use. Special attention is given to the influence of ultraviolet (UV) radiation and mechanical loads on PCM degradation. The text presents research findings related to polymer degradation under UV radiation, the impact of UV exposure on the mechanical properties of carbon fiber-reinforced polymer composites, as well as the mechanisms of yellowing in thin films of epoxy and vinyl ester resins.
Entre arrogance et microagression linguistiques
Authors: Arrighi Laurence
Published: January 2024

Dans cette contribution, je propose l’interprétation d’une réaction individuelle face à des pratiques de marquage du discours rapporté utilisées dans des médias en milieu linguistique minoritaire (l’apposition à la suite de propos présentant des particularismes linguistiques locaux d’un (sic) ainsi que divers marquages métadiscursifs type « nous dit-il avec son charmant accent acadien »). Une recherche systématique au sein d’un corpus montre que ces pratiques sont notables bien que peu courantes. Ces pratiques relèvent sans doute de techniques professionnelles bien établies. Il n’en demeure pas moins qu’elles peuvent s’avérer indélicates envers la communauté que ces médias desservent ce dont témoigne la réaction individuelle que je prends comme point de départ. Je propose que l’on peut voir dans ces pratiques une forme d’arrogance linguistique (Messaoudi 2021) constituant une micro-agression linguistique (Razafimandimbimanana et Wacalie 2020) de plus auxquelles font face les minorités linguistiques.
Spider Matrix: Towards Research Paper Evaluation and Innovation for Everyone
Authors: XU Yanheng , Ye Shuqian , Liu Rulin , Shao Ling , Zhu Xi
Published: January 2024

This study investigates the transformative effects of Artificial Intelligence (AI) on academic publishing, emphasizing the innovative Spider Matrix system. Designed for public use, this platform enables users to assess research papers and identify groundbreaking aspects. It addresses the challenges posed by the growing volume of publications and the imperative to uphold quality in scholarly communication. The paper highlights AI's pivotal role in enhancing the peer-review process. Through the Spider Matrix case study, the paper demonstrates AI's utility in appraising academic papers and patents across various dimensions, such as originality, robustness, and impact. This system goes beyond conventional metrics like citation counts, offering prompt, equitable evaluations grounded in the intrinsic quality of each work. Its adaptability to different academic fields and patent analysis underscores its versatility and efficacy in providing a more equitable and comprehensive framework for scholarly assessment. Additionally, the system is noted for its ability to generate innovative ideas from significant evaluation results. This paper emphasizes AI's potential to revolutionize academic guidance, publishing, and the generation of innovative ideas, aligning with the growing need for more meaningful and substantial research impact metrics. Ultimately, this leads to higher quality research outputs.
The Cyanoketene Anion [NC3O]-
Authors: Krischer Felix , Swamy Varre S. V. S. N. , Feichtner Kai-Stephan , Ward Robert J. , Gessner Viktoria H.
Published: January 2024

Cumulenes and heterocumulenes with three or more cumulative multiple bonds are usually reactive species, that serve as valuable building blocks to more complex molecules but tend to isomerize or cyclize and therefore are difficult to isolate. Until to date, numerous (hetero)cumulenes have been detected in the interstellar medium and are assumed to be important intermediates in prebiotic chemistry, in particular when containing nitrogen and oxygen functionalities. Using a mild ligand exchange reaction at carbon in metalated ylides, we have now succeeded in the synthesis and gram-scale isolation of the so far elusive cyanoketene anion, [NC3O]-. Despite its assumed cumulene-like structure and the delocalization of the negative charge across the whole 5-atomic molecule, it features a bent geometry in solid state with a nucleophilic central carbon atom. Computational studies reveal an ambiguous bonding situation in the anion, which can only be illustrated by a combination of different resonance structures. Nonetheless, the anion features a remarkable stability, thus allowing the storage of its potassium salt and its application as highly functional synthetic building block. The cyanoketene anion readily reacts with a series of small molecules to more complex organic compounds including industrially valuable compounds such as cyanoacetate. This work demonstrates that reactive species found in the interstellar medium can be made accessible by novel synthesis methods and open up new pathways to more complex compounds through reaction with small molecules, an atom economic strategy sought in sustainable chemistry.
Molecular Basis for Chemoselectivity Control in Oxidations of Internal Aryl-Alkenes Catalyzed by Laboratory Evolved P450s
Authors: Soler Jordi , Gergel Sebastian , Hammer Stephan , Garcia-Borràs Marc
Published: January 2024

P450 enzymes naturally perform selective hydroxylations and epoxidations of unfunctionalized hydrocarbon substrates, among other reactions. The adaptation of P450 enzymes to a particular oxidative reaction involving alkenes is of great interest for the design of new synthetically useful biocatalysts. However, the mechanism that these enzymes utilize to precisely modulate the chemoselectivity and distinguishing between competing alkene double bond oxidations and allylic hydroxylations is sometimes not clear, which hampers the rational design of specific biocatalysts. In a previous work, a P450 from Labrenzia aggregata (P450LA1) was engineered in the laboratory using directed evolution to catalyze the direct oxidation of trans-b- methylstyrene to phenylacetone. The final variant, KS, was able to overcome the intrinsic preference for alkene epoxidation to directly generate a ketone product via the formation of a highly reactive carbocation intermediate. Here, additional library screening along the evolutionary lineage permitted to serendipitously detect a mutation that overcomes epoxidation and carbonyl formation by exhibiting a large selectivity towards allylic oxidation. A multiscalar computational methodology was applied to reveal the molecular basis towards this hydroxylation preference. Enzyme modelling suggests that introduction of a bulky substitution dramatically changes the accessible conformations of the substrate in the active site, thus modifying the enzymatic selectivity towards terminal hydroxylation and avoiding the competing epoxidation pathway, which is sterically hindered.
Los villanos en el cine: una ominosa genealogía
Authors: León Frías Isaac
Published: January 2024

Este texto establece una línea de tiempo sobre la villanía en la historia del cine: desde la época silente hasta los supervillanos de multiversos, pasando por los antiguos y nuevos monstruos, los gangsters, el film noir, la obra del mítico Alfred Hitchcock o los antagonistas de la franquicia del agente 007, James Bond.
Alphaville: género, inteligencia artificial y otros asuntos políticos
Authors: Isa Kohatsu Hitoshi
Published: January 2024

Alphaville es notable en la obra de Jean-Luc Godard —a quien le dedicamos nuestra edición anterior— por su acercamiento a la ciencia ficción. El uso de este género sirve, a través de la naturaleza iconoclasta de la nouvelle vague y las propias sensibilidades del director, para deconstruir los ideales modernistas y las propias bases de la ciencia ficción. Asimismo, se adelanta a visiones futuras de la inteligencia artificial, enfocada en esta cinta como una presencia villana.
Evidencias, Transformaciones y Desplazamientos del Cuerpo en Sociedades Distópicas:
Authors: Caro María Cristina
Published: January 2024

El propósito de este escrito es presentar apartes de los resultados obtenidos en el proceso de investigación de mi tesis de Maestría, titulado Lecciones de anatomía femenina: Una lectura preliminar a la obra de Libia Posada 1998-2014. He agrupado los resultados en tres apartados: Un blanco perverso, Transformaciones y Desplazamientos del Cuerpo en Sociedades Distópicas, y Evidencias sensibles. Los ejes conceptuales que guían el desarrollo de la investigación son: una introducción a la vida y obra de la artista; una descripción de sus obras en términos conceptuales y formales, a partir de las metodologías de la historia del arte con una perspectiva feminista; y, el desarrollo de unas reflexiones sobre el lugar de la mujer en su trabajo artístico. Estos ejes continuamente dialogan con una entrevista con la artista, que permite un mayor acercamiento y comprensión de su obra. Lo anterior sobre la hipótesis de que experimentar la vida desde un cuerpo configurado como femenino, con una experiencia subjetiva, afecta la producción artística, haciendo evidentes elementos o preocupaciones femeninas, feministas o no, que puedan ser características en el arte hecho por mujeres.
Discursos de Género y Feministas en la Prensa Web Femenina en Argentina.
Authors: Schaufler María Laura
Published: January 2024

El artículo aborda la inserción de discursos feministas en la prensa femenina de actualidad en Argentina. Para ello explora las construcciones discursivas en torno a las categorías de género y feminismo en el sitio web de la revista OHLALÁ, entre 2018 y 2020, años marcados por la mediatización del debate por la Ley N° 27.610 de Interrupción Voluntaria del Embarazo. Con objetivo general de identificar la injerencia de tópicos y consignas del movimiento feminista actual en el país, en un medio de comunicación destinado históricamente a la construcción de lo femenino, analiza los usos de las nociones de género y feminismo en la producción discursiva de feminidades en OHLALÁ. Con la intención de indagar acerca de las estrategias discursivas desde las cuales el feminismo se cuela en la prensa femenina y discute aquello que parecía fijo, inmutable y natural, interroga qué nuevas exclusiones instalan estos discursos. Entre los resultados se encuentran en OHLALÁ discursos feministas articulados a una concepción de la feminidad contemporánea asociada a nuevas normas: la sororidad, la empresariedad, la movilización, la crítica, la formación, la diferencia y diversidad, sobre el telón de fondo de un feminismo blanco, cisgénero, de clase media, metropolitano y heteronormativo. El feminismo se presenta, por una parte, de forma espectacularizada, encarnado en celebridades, lo que lo torna más visible, accesible y deseable. Se asocia a prácticas y valores del neoliberalismo, produciendo discursos donde iniciativas personales e innovadoras son entendidas como prácticas feministas. Por otra parte, produce discursos que hablan de la popularización del movimiento feminista, divulga su historia, informa y aboga por las leyes sobre derechos sexuales, e insta a participar de las marchas. De esta manera, la incorporación de nociones del feminismo presenta un momento de inflexión en que feminismo(s) y feminidad(es) no son alternativas opuestas, sino que se encuentran entrelazadas.
Incidencia del liderazgo directivo/docente en el rendimiento académico de instituciones colombianas
Authors: Vargas Valencia Eucaris , Restrepo Pizarro Lina Marcela , Villamil Stelver Giovanny
Published: January 2024

En el presente artículo se muestra los resultados de un estudio en el que participan dos instituciones colombianas, cuyo objetivo es determinar la incidencia del liderazgo directivo y docente en el rendimiento académico de los estudiantes. En el desarrollo de este, se hace uso de una metodología mixta (cuantitativa y cualitativa) a través de entrevistas y cuestionarios que miden los estilos de liderazgo que aplican los directivos de las instituciones educativas escogidas, así mismo, se acude a la estadística para observar el rendimiento de los estudiantes en cinco áreas fundamentales evaluadas en las Pruebas Saber. Como resultado se evidencian practicas similares en los estilos de liderazgo aplicados por los docentes y directivos de ambas instituciones, lo cual indica que no existió una incidencia directa.
Determinants of Import in ASEAN Economic Community
Authors: Yuliadi Imamudin , Basuki Agus Tri , Ayuningtyaswati Delya
Published: January 2024

Introduction: Imports are an important component of economic development in developing countries, including in the ASEAN Economic Community.
 
Purpose: The aims of this study to analyze the determinants of import in ASEAN Economic Community.
 
Methodology/Approach: The research method used is panel data analysis from 2010-2019. The research variables include imports as the dependent variable and export variables, exchange rates, population, inflation, GDP and interest rates as independent variables. This study is to analyze the determinants of imports in the economies of ASEAN community countries starting from the results of the Chow test and Hausmen test which compare the static and dynamic fixed effect panel data analysis models.
 
Findings: The results of this study indicate that imports for ASEAN economic community are influenced by the variables of exports, FDI and population. The results of this study also show that imports for ASEAN economic community are a necessity to support their economic development.
 
Originality/Value/Implication: The conclusion and recommendation from this research is that imports are an important component in economic development in ASEAN economic community, so it is necessary to have an integrated policy among ASEAN economic community to build economic cooperation to reduce economic dependence from outside. ASEAN economic community need to improve economic efficiency and international competitiveness to encourage exports of flagship products in international markets.