bluuebunny/crossref_metadata_2025 huggingface dataset:
From Broca and Wernicke to the Neuromodulation Era: Insights of Brain Language Networks for Neurorehabilitation
Authors: Nasios Grigorios , Dardiotis Efthymios , Messinis Lambros
Published: July 2019

Communication in humans activates almost every part of the brain. Of course, the use of language predominates, but other cognitive functions such as attention, memory, emotion, and executive processes are also involved. However, in order to explain how our brain “understands,” “speaks,” and “writes,” and in order to rehabilitate aphasic disorders, neuroscience has faced the challenge for years to reveal the responsible neural networks. Broca and Wernicke (and Lichtheim and many others), during the 19th century, when brain research was mainly observational and autopsy driven, offered fundamental knowledge about the brain and language, so the Wernicke-Geschwind model appeared and aphasiology during the 20th century was based on it. This model is still useful for a first approach into the classical categorization of aphasic syndromes, but it is outdated, because it does not adequately describe the neural networks relevant for language, and it offers a modular perspective, focusing mainly on cortical structures. During the last three decades, neuroscience conquered new imaging, recording, and manipulation techniques for brain research, and a new model of the functional neuroanatomy of language was developed, the dual stream model, consisting of two interacting networks (“streams”), one ventral, bilaterally organized, for language comprehension, and one dorsal, left hemisphere dominant, for production. This new model also has its limitations but helps us to understand, among others, why patients with different brain lesions can have similar language impairments. Furthermore, interesting aspects arise from studying language functions in aging brains (and also in young, developing brains) and in cognitively impaired patients and neuromodulation effects on reorganization of brain networks subserving language. In this selective review, we discuss methods for coupling new knowledge regarding the functional reorganization of the brain with sophisticated techniques capable of activating the available supportive networks in order to provide improved neurorehabilitation strategies for people suffering from neurogenic communication disorders.
The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity
Authors: Palakurthi Sangeetha , Kuraguchi Mari , Zacharek Sima J. , Zudaire Enrique , Huang Wei , Bonal Dennis M. , Liu Jeffrey , Dhaneshwar Abha , DePeaux Kristin , Gowaski Martha R. , Bailey Dyane , Regan Samuel N. , Ivanova Elena , Ferrante Catherine , English Jessie M. , Khosla Aditya , Beck Andrew H. , Rytlewski Julie A. , Sanders Catherine , Laquerre Sylvie , Bittinger Mark A. , Kirschmeier Paul T. , Packman Kathryn , Janne Pasi A. , Moy Christopher , Wong Kwok-Kin , Verona Raluca I. , Lorenzi Matthew V.
Published: July 2019

The success of targeted or immune therapies is often hampered by the emergence of resistance and/or clinical benefit in only a subset of patients. We hypothesized that combining targeted therapy with immune modulation would show enhanced antitumor responses. Here, we explored the combination potential of erdafitinib, a fibroblast growth factor receptor (FGFR) inhibitor under clinical development, with PD-1 blockade in an autochthonous FGFR2K660N/p53mut lung cancer mouse model. Erdafitinib monotherapy treatment resulted in substantial tumor control but no significant survival benefit. Although anti–PD-1 alone was ineffective, the erdafitinib and anti–PD-1 combination induced significant tumor regression and improved survival. For both erdafitinib monotherapy and combination treatments, tumor control was accompanied by tumor-intrinsic, FGFR pathway inhibition, increased T-cell infiltration, decreased regulatory T cells, and downregulation of PD-L1 expression on tumor cells. These effects were not observed in a KRASG12C-mutant genetically engineered mouse model, which is insensitive to FGFR inhibition, indicating that the immune changes mediated by erdafitinib may be initiated as a consequence of tumor cell killing. A decreased fraction of tumor-associated macrophages also occurred but only in combination-treated tumors. Treatment with erdafitinib decreased T-cell receptor (TCR) clonality, reflecting a broadening of the TCR repertoire induced by tumor cell death, whereas combination with anti–PD-1 led to increased TCR clonality, suggesting a more focused antitumor T-cell response. Our results showed that the combination of erdafitinib and anti–PD-1 drives expansion of T-cell clones and immunologic changes in the tumor microenvironment to support enhanced antitumor immunity and survival.
Survivin Impairs the Apoptotic Machinery in CD4+ T Cells of Patients with Ulcerative Colitis
Authors: Feng Bai-Sui , Ma Na , Zhang Yuan-Yi , Gao Han , Zhang Cui , Li Gengfeng , Liu Zhanju , Feng Yisheng , Yu Hai-Qiong , Xiao Liang , Liu Zhi-Gang , Yang Ping-Chang
Published: July 2019

Background: The increase in CD4+ T cell infiltration and overproduction of CD4+ T cell-associated cytokines have been observed in the inflamed colon mucosa of patients with ulcerative colitis (UC); the underlying mechanisms are not fully understood. Survivin plays a critical role in the interference with apoptotic machinery. This study aims to elucidate the role of survivin in the interference with the apoptotic machinery in CD4+ T cells of UC patients. Methods: Peripheral blood samples were collected from UC patients (UC group) and healthy subjects (healthy group). The apoptotic status in CD4+ T cells was analyzed by flow cytometry. Results: We observed that the expression of survivin was significantly higher in CD4+ T cells of UC patients than in healthy subjects. UC CD4+ T cells were resistant to apoptosis induction. A complex of survivin and c-Myc, the transcription factor of FasL, was detected in CD4+ T cells in UC patients, which prevented the binding of c-Myc to the FasL promoter and interfered with the expression of FasL. Increased expression of survivin prevented the activation-induced CD4+ T cells from apoptosis. Conclusions: The data indicate that UC CD4+ T cells express high levels of survivin, which impairs the apoptotic machinery in CD4+ T cells and prevents the activation-induced CD4+ T cell apoptosis. Therefore, target therapy against survivin has translational potential in the treatment of UC patients.
Frailty Assessment in Animal Models
Authors: Heinze-Milne Stefan D. , Banga Shubham , Howlett Susan E.
Published: July 2019

Although frailty has been extensively investigated for the last 2 decades, preclinical models of frailty have only been developed over the past decade. Frailty is a concept that helps to explain the difference between chronologic age and biologic age and to discuss health span along with lifespan. In general, a frail individual will be more susceptible to adverse health outcomes than a healthy, nonfrail individual of the same age. However, the biology and mechanisms of frailty are still unclear. The development of preclinical models of frailty and frailty assessment tools are invaluable to geriatric research. This review briefly describes the concept of frailty and discusses the newly developed animal models of frailty, specifically the frailty phenotype- and frailty index-based models. Mouse models are the most common models for preclinical frailty research, but rat and canine models for frailty assessment have also been developed. These models can facilitate the testing of frailty-specific treatments and help to investigate the effects of various interventions on frailty. Similarities and differences between human and animal models, including sex differences in frailty, are also discussed. The availability of animal models of frailty is a valuable and welcome addition to the study of frailty, aging, or the disorders of old age and will enable a better understanding of frailty mechanisms.
Overcoming Tamoxifen Resistance by Regulation of Del-1 in Breast Cancer
Authors: Lee Jeeyeon , Jeong Jae-Hwan , Jung Jin Hyang , Kim Wan Wook , Lee Soo Jung , Park Ji-Young , Park Jee Young , Kang Seung Hee , Kim Eun Ae , Park Jae Hyung , Chae Yee Soo , Park Ho Yong
Published: July 2019

Background: Hormone receptor-positive breast cancer accounts for nearly two-thirds of breast cancer cases; it ultimately acquires resistance during endocrine treatment and becomes more aggressive. This study evaluated the role of developmental endothelial locus (Del)-1 in tamoxifen-resistant (TAM-R) breast cancer. Methods: Del-1 expression in recurrent TAM-R breast cancer tissue was evaluated and compared to that in the original tumor tissue from the same patients. Del-1 expression was also evaluated in TAM-R cells by quantitative real-time PCR, western blotting, and enzyme-linked immunosorbent assay. The effects of Del-1 knockdown on the proliferation, migration, and invasion of TAM-R cells was assessed with wound-healing and Matrigel transwell assays. Results: Del-1 was more highly expressed in recurrent breast cancer as compared to the original tumor tissues before initiation of endocrine treatment. Del-1 mRNA was upregulated in TAM-R and small interfering RNA-mediated knockdown of Del-1 suppressed the migration and proliferation of TAM-R cells while partly restoring TAM sensitivity. And the TAM resistance was recovered by knockdown of Del-1. Conclusions: TAM-R breast cancer is characterized by Del-1 overexpression and tumor progression can be inhibited by Del-1 depletion, which restores TAM sensitivity. Thus, therapeutic strategies that target Del-1 may be effective for the treatment of hormone-resistant breast cancer.
A Higher Rate of Pulmonary Fungal Infection in Chronic Obstructive Pulmonary Disease Patients with Influenza in a Large Tertiary Hospital
Authors: Xu Linrui , Chen Bojiang , Wang Faping , Wei Chuanqi , Liu Huan , Liu Jia , Herth Felix J.F. , Luo Fengming
Published: July 2019

Background: Influenza is considered a self-limiting disease. However, in patients with chronic obstructive pulmonary disease (COPD), it may result in serious outcomes during the flu season. Objectives: The aims of this retrospective study were to explore the characteristics of hospitalized patients with COPD complicated by influenza and determine the factors affecting the prognosis of these patients. Method: Demographic and clinical data were collected for 278 patients totally from the West China Hospital between January 1, 2016 and February 28, 2018. Results: Among the patients with influenza, the positive fungal culture rate, and the rates of antifungal drug and systemic corticosteroids use were higher for those with COPD than for those without COPD. Respiratory failure was more common in patients with influenza and COPD than in patients with influenza only, while the proportion of severe cases was higher among the former than among the latter. Among the patients with COPD, the positive fungal culture rate, particularly for Aspergillus, and the rate of systemic corticosteroids use were higher for those with influenza than for those without influenza. Multivariate analysis revealed that a COPD history of >20 years and smoking for >20 pack-years were independent factors for susceptibility of COPD patients to influenza. Conclusions: Aspergillus infection seems to be more common in patients with influenza and COPD. In addition, COPD complicated by influenza during the seasonal outbreak can easily progress to a severe disease state. Heavy smokers and patients with a prolonged COPD history are more likely to be infected by influenza.
A Systematic Review of Substance Use (Disorder) in Individuals with Mild to Borderline Intellectual Disability
Authors: van Duijvenbode Neomi , VanDerNagel Joanne E.L.
Published: July 2019

Although the attention for substance use (SU) and SU disorders (SUD) among individuals with mild to borderline intellectual disability (MBID) has been growing exponentially, this form of dual diagnosis has largely been ignored by addiction medicine. In this article, we systematically review the research between January 2000 and June 2018 on the prevalence, assessment, and treatment of SU(D) among children, adolescents, and adults with MBID. A total of 138 articles were included. It is concluded that individuals with MBID are likely to be at a higher risk for developing SUD compared to those without MBID. Future research should focus on the detection of MBID among patients being treated in addiction medicine, the development and implementation of systematic assessment methods of SU(D) among individuals with MBID, and the development and evaluation of prevention and treatment interventions. System integration, interdisciplinary collaboration, and the development of tailored treatment for individuals with MBID are advised to improve treatment access and outcome for those who have developed SUD.
The Value of Diagnostic Information in Personalised Healthcare: A Comprehensive Concept to Facilitate Bringing This Technology into Healthcare Systems
Authors: Wurcel Victoria , Cicchetti Americo , Garrison Louis , Kip Michelle M.A. , Koffijberg Hendrik , Kolbe Anne , Leeflang Mariska M.G. , Merlin Tracy , Mestre-Ferrandiz Jorge , Oortwijn Wija , Oosterwijk Cor , Tunis Sean , Zamora Bernarda
Published: July 2019

Health systems around the world seek to address patients’ unmet health needs for a range of acute and chronic diseases. Simultaneously, governments strive to keep healthcare spending sustainable, while providing equal access to high-quality care. This has fuelled debate around what constitutes a valuable healthcare intervention in a health system and the corollary consideration of what governments are willing to pay for a certain health intervention. Until recently, the value of information in general, and the value of diagnostic information (VODI) specifically, was not part of the discussion.However, investment in diagnostic information can be a key development as information may guide more effective and efficient healthcare and help maintain an affordable health system. This paper therefore explores ways to best define, evaluate, and reward the value created from diagnostics in healthcare and how to include these value considerations in decision-making processes for diagnostics. The authors ultimately call for a holistic VODI framework that accounts for the full range of potential benefits of diagnostic testing, beyond the traditional clinical and health economic domains, and that is essential to recognise, measure, and fully leverage the benefits of diagnostics for patients, health systems, and society.
Sistemas de Informações Geográficas e seus visualizadores tridimensionais para o ensino do projeto de Arquitetura e Urbanismo
Authors: Souza Renato Cesar Ferreira de
Published: July 2019

Estuda-se o apoio de Sistemas de Informações Geográficas (SIG) para o ensino de projetos de Arquitetura e Urbanismo. Esperava-se que estudantes alcançassem maior rapidez na tomada de decisões gerando hipóteses projetuais e testando-as, o quê hipoteticamente, resultaria em soluções de projeto mais criativas e detalhadas. Observação e avaliação dos produtos gerados demonstraram que o potencial das ferramentas depende do ajuste do tempo de aprendizagem do uso do SIG. Os resultados apresentaram projetos majoritariamente derivados de hipóteses únicas. Pesquisas futuras estudarão a criatividade na geração de hipóteses projetuais com apoio do instrumental, mas considerando diversos problemas de projeto na proposta de ensino.
Sobre o feminicídio, o direito da mulher de nomear suas experiências
Authors: Romio Jackeline Aparecida Ferreira
Published: July 2019

No artigo argumenta-se a necessidade de analisar a violência e a morte de mulheres de maneira a entendê-la dentro do quadro complexo das políticas de controle do corpo e sexualidade. Este tipo de abordagem tem sido especialmente produzido por feministas através da caracterização do fenômeno denominado feminicídio. O texto analisa e explica como o conceito de feminicídios foi se modernizando e se amplificando e se adequando às realidades nacionais latino-americanas ao se propagarem enquanto lei.
Engolidas pela onda azul
Authors: Rangel Patrícia , Dultra Eneida Vinhaes Bello
Published: July 2019

Este texto ensaístico aborda alguns exemplos de medidas adotadas pelo governo que assumiu a Presidência da República no Brasil após a destituição da presidenta Dilma Rousseff, em 2016, apontando retrocessos institucionais no campo das políticas de igualdade de gênero, em um contexto de conservadorismo político e de riscos à efetividade de direitos sociais para as mulheres. Na última década, foram registrados avanços no combate às desigualdades de gênero e raciais, sobretudo através das políticas transversais impulsionadas pelas Secretarias Nacional de Políticas para as Mulheres (SPM) e de Promoção de Políticas da Igualdade Racial (SEPPIR) – posteriormente, reunidas no Ministério das Mulheres, da Igualdade Racial e dos Direitos Humanos –, que restaram prejudicadas em virtude da reforma ministerial, levada a cabo por Michel Temer, que alterou a organização administrativa do Estado, subjugando as competências e a estrutura das pastas específicas das Mulheres, da Igualdade Racial e dos Direitos Humanos para o Ministério interino da Justiça e Cidadania. Considerando o perfil conservador denotado desde a composição do governo provisório, notava-se a tendência de inferiorizar essas áreas temáticas, cuja evolução, tanto política quanto social, diziam respeito a uma conquista da sociedade brasileira. Observando tais movimentos, este ensaio comenta, sem pretensão científica, progressivos sinais de desmontes de direitos das mulheres e das políticas de igualdade de gênero, ao longo dos últimos dois anos, com perdas substantivas em relação ao período anterior e baixa expectativa de retorno diante do resultado das eleições de 2018.
Resenha de 'Lélia Gonzalez: primavera para as rosas negras', de Lélia Gonzales
Authors: Gonçalves Renata
Published: July 2019

Referência completa:

Gonzalez, Lélia. Lélia Gonzalez: primavera para as rosas negras. São Paulo: UCPA Editora, 2018.
A noção de campo de uma perspectiva transnacional
Authors: Sapiro Gisèle , Stella Marcello G. P.
Published: July 2019

Referência para o artigo original: Sapiro, Gisèle. Le champ est-il national ? La théorie de la différenciation sociale au prisme de l’histoire globale. Actes de la recherche en sciences sociales, (N°200), p. 70-85, 2013/5. DOI 10.3917/arss.200.0070
Camk2n1
Is a Negative Regulator of Blood Pressure, Left Ventricular Mass, Insulin Sensitivity, and Promotes Adiposity
Authors: Alfazema Neza , Barrier Marjorie , de Procé Sophie Marion , Menzies Robert I. , Carter Roderick , Stewart Kevin , Diaz Ana Garcia , Moyon Ben , Webster Zoe , Bellamy Christopher O.C. , Arends Mark J. , Stimson Roland H. , Morton Nicholas M. , Aitman Timothy J. , Coan Philip M.
Published: July 2019

Metabolic syndrome is a cause of coronary artery disease and type 2 diabetes mellitus.
Camk2n1
resides in genomic loci for blood pressure, left ventricle mass, and type 2 diabetes mellitus, and in the spontaneously hypertensive rat model of metabolic syndrome,
Camk2n1
expression is cis-regulated in left ventricle and fat and positively correlates with adiposity. Therefore, we knocked out
Camk2n1
in spontaneously hypertensive rat to investigate its role in metabolic syndrome. Compared with spontaneously hypertensive rat,
Camk2n1
−/−
rats had reduced cardiorenal CaMKII (Ca
2+
/calmodulin-dependent kinase II) activity, lower blood pressure, enhanced nitric oxide bioavailability, and reduced left ventricle mass associated with altered hypertrophic networks. Camk2n1 deficiency reduced insulin resistance, visceral fat, and adipogenic capacity through the altered cell cycle and complement pathways, independent of CaMKII. In human visceral fat,
CAMK2N1
expression correlated with adiposity and genomic variants that increase
CAMK2N1
expression associated with increased risk of coronary artery disease and type 2 diabetes mellitus. Camk2n1 regulates multiple networks that control metabolic syndrome traits and merits further investigation as a therapeutic target in humans.
Changing Patterns of Carotid Endarterectomy Between 2011 and 2017 in England
Authors: Johal Amundeep S. , Loftus Ian M. , Boyle Jonathan R. , Naylor A. Ross , Waton Sam , Heikkila Katriina , Cromwell David A.
Published: July 2019

Background and Purpose—

Carotid endarterectomy (CEA) reduces the risk of stroke in recently symptomatic patients and less so in asymptomatic patients. Recent evidence suggests that the number of CEAs may be declining. The aim of this study was to investigate annual patterns of CEA in asymptomatic and symptomatic patients in England from 2011 to 2017.

Methods—

Data from the National Vascular Registry were used to describe (1) the number of CEA procedures in England and its 9 geographic regions from 2011 to 2017, (2) the characteristics of patients undergoing CEA, and (3) whether rates of CEA correlated with the number of vascular arterial units within each region. Annual stroke incidence for each region was derived from official population figures and the number of index stroke admissions per year.

Results—

The overall number of CEAs performed in England fell from 4992 in 2011 to 3482 in 2017, a 30% decline. Among symptomatic patients, there was a 25% decline, the number of CEAs falling from 4270 to 3217. In asymptomatic patients, there were 722 CEAs performed in 2011 and 265 in 2017, a 63% decline. CEAs per 100 000 adults within all regions declined over time but the size of change varied across the regions (range, 1.7–5.5 per 100 000). The regional numbers of CEAs per year were associated with changes in the regional stroke incidence, the proportion of CEAs performed in asymptomatic patients, and the number of hospitals performing CEA.

Conclusions—

This population-based study revealed a 63% decline in CEAs among asymptomatic patients between 2011 and 2017, possibly because of changing attitudes in the role of CEA. Reasons for the 25% decline in CEAs among symptomatic patients are unclear as UK guidelines on CEA have not changed for these patients. Whether the proportion of symptomatic patients with 50% to 99% ipsilateral stenosis has changed requires investigation.
The Trained Particles Circus: Dealing with Attractors, Automatons, Ghosts and Their Shadows
Authors: Araujo Patxi
Published: July 2019

The Trained Particles Circus proposes an improbable, precarious and potentially dangerous meeting place caged between the real and the virtual worlds. Embodied in the relationship between synthetic biomechanics and an automaton, it recreates the figure of the circus artist, the puppet with its own life or the fantastic animal; and it places us as spectators into a contemporary spectacle of hybrid and augmented subjects that conjugate light and shadow, fake and magic, virtual and physical reality, machine and organism [1].
The genus Pseudachorutes Tullberg, 1871 (Collembola, Neanuridae) in the Ukraine with descriptions of new species
Authors: KAPRUS’ IGHOR J. , WEINER WANDA M.
Published: July 2019

Four new species of Pseudachorutes from Ukraine are described and illustrated: P. vitalii sp. nov., P. scythicus sp. nov., P. vasylii sp. nov. and P. janstachi sp. nov. These new species differ in the body size, in the details of body chaetotaxy, in the number of vesicles of PAO, in the shape of mandibles, in the chaetotaxy of labrum and labium. The following species are redescribed on the basis of Ukrainian material: Pseudachorutes pratensis Rusek, 1973, Pseudachorutes palmiensis Börner, 1903, Pseudachorutes parvulus Börner, 1901, Pseudachorutes subcrassus Tullberg, 1871, Pseudachorutes dubius Krausbauer, 1898 and Pseudachorutes corticicolus (Schäffer, 1896). A key to the Ukrainian Pseudachorutes species are given, too.
A new Notacanthurus Tshernova, 1974 and a new Rhithrogena Eaton, 1881 (subgenus Tumungula Zhou & Peters, 2004) from Thailand (Heptageniidae, Ephemeroptera)
Authors: BRAASCH DIETRICH , BOONSOONG BOONSATIEN
Published: July 2019

Notacanthurus baei sp. n. (larva) and Rhithrogena (Tumungula) siamensis sp. n. (male, female and assumed larva) are described from northern Thailand. Diagnoses and line drawings of key characters are provided. Larvae of Southeast Asian Notacanthurus n.sp. resemble those of Palearctic Notacanthurus spp. in having a median ridge of spines directed posteriorly on terga, a similar patterning of terga with oblique stripes sloping inward, femoral cross bands and caudal filaments with whorls of small spines. Contrastingly, larvae of the new species bear claws with denticles, while the mature male larva exhibits prospective penis with distally paired portions of rounded lobes like those in most Electrogena Zurwerra and Tomka, 1984. Imagines of R. (T.) siamensis represent a second species of subgen. Tumungula Zhou and Peters, 2004. Males have balloon-shaped hypertrophied foreclaws, with first tarsal segment about 1.4x the length of the second, and divergent penis lobes without titillators. In contrast to R. (T.) unica the male styliger plate shows two sharp, inside directed projections, submedian lobes of the penis have circular gonopores lacking subapical spines.
Bilyjomyia, a new genus of the tribe Macropelopiini from the Holarctic (Diptera: Chironomidae)
Authors: NIITSUMA HIROMI , WATSON JR. CHARLES N.
Published: July 2019

The genus Bilyjomyia is erected for Apsectrotanypus algens (Coquillett, 1902) from western North America and B. fontana n. sp. from Japan. A generic diagnosis and a description are given for all life stages. Bilyjomyia algens is redescribed. All life stages of Bilyjomyia fontana are described and figured. The new genus shows affinities to Macropelopia Thienemann and Bethbilbeckia Fittkau et Murray in the immature stages. Bilyjomyia can be distinguished from all other known Macropelopiini by the following features: the reduced setation of T.IX and the restriction of these setae to the tergal posterior edge in the adult male; the aeropyles of the thoracic horn in the pupa; the labral sclerite and the position and form of the ventral cephalic setae in the larva. The distribution of Bilyjomyia indicates dispersal across the Bering Land Bridge, a pattern known in some other genera of Chironomidae and other orders of insects.
Revision of the Agrilus muscarius species-group (Coleoptera: Buprestidae) with description of thirteen new species from Palaearctic and Oriental regions
Authors: JENDEK EDUARD , GREBENNIKOV VASILY V.
Published: July 2019

The Agrilus muscarius species-group (Coleoptera, Buprestidae, Agrilinae) is defined to include twenty-nine species, thirteen of which are described herein: A. apicaureus Jendek, sp. nov. (north Laos); A. carinelytratus Jendek, sp. nov. (mainland Malaysia); A. cuneatus Jendek, sp. nov. (Thailand); A. dilatipenis Jendek, sp. nov. (Thailand); A. haucki Jendek, sp. nov. (Malaysia: Pahang); A. hunanus Jendek, sp. nov. (China: Hunan); A. madanensis Jendek, sp. nov. (south Vietnam); A. pseudoharlequin Jendek, sp. nov. (Indonesia: Java); A. rolciki Jendek, sp. nov. (India: Assam); A. semicaducus Jendek, sp. nov. (north Laos); A. spiculipenis Jendek, sp. nov. (Thailand, Vietnam); A. tiomanensis Jendek, sp. nov. (Malaysia: Tioman island); A. ventrituber Jendek, sp. nov. (Myanmar, north Thailand). Agrilus aurarius (Kerremans, 1892) comb. nov. is transferred from the genus Meliboeus. Two new synonyms are proposed for A. aurarius (Kerremans, 1892) comb. nov. (= A. bocae Descarpentries & Villiers, 1963 syn. nov.) and A. muscarius Kerremans, 1895 (= A. seladon Obenberger, 1940 syn. nov.). A lectotype is designated for A. muscarius Kerremans, 1895. Members of the group are illustrated and an identification key is provided.
Apaturinae (Lepidoptera: Nymphalidae) from the Korean Peninsula: Synonymic Lists and Keys to Tribes, Genera and Species
Authors: LEE YOUNG JUNE
Published: July 2019

This paper provides keys to tribes, genera and species and synonymic lists for the 12 butterfly species belonging to eight genera of Apaturinae (Lepidoptera: Nymphalidae) from the Korean Peninsula: Apatura ilia (Denis and Schiffermüller), Apatura metis Freyer, Apatura iris (Linnaeus), Hestina japonica (Felder and Felder), Hestina assimilis (Linnaeus), Sasakia charonda (Hewitson), Mimathyma schrenckii (Ménétriès), Mimathyma nycteis (Ménétriès), Sephisa princeps (Fixsen), Chitoria ulupi (Doherty), Dilipa fenestra (Leech) and Dichorragia nesimachus (Doyère). Species accounts include brief summaries of each taxon’s biology, taxonomy and life history. The distributional ranges of the Hestina persimilis species complex are discussed and illustrated.
A revision of the genus Gondwanoscurus Jezek (Diptera: Psychodidae)
Authors: CURLER GREGORY R.
Published: July 2019

Gondwanoscurus Jezek (Psychodidae: Psychodinae) is revised to include seven species. Gondwanoscurus cruciferus sp. nov. and G. ornithostylus sp. nov. from Thailand are described. Three described species are transferred from Telmatoscopus Eaton to Gondwanoscurus: G. ejundicus (Quate), G. eximius (Quate) and G. praecipuus (Quate). The adult male and female of G. ejundicus and G. mcclurei (Quate) and the adult male of G. eximius and G. praecipuus are redescribed. Keys to adult males of the seven known species and females of the four species for which they are known are provided, and the relationship of Gondwanoscurus to other Paramormiine genera is discussed.
New species and records of Oxyethira Eaton (Trichoptera: Hydroptilidae) from Amazonas State, Brazil
Authors: SANTOS ALLAN PAULO MOREIRA , HENRIQUES-OLIVEIRA ANA LUCIA , NESSIMIAN JORGE LUIZ
Published: July 2019

Three new species of Oxyethira Eaton, 1873—O. luanae sp. nov., O. sinistra sp. nov., and O. longipenis sp. nov.—are described and illustrated from male specimens collected in Amazonas State, Brazil. Six described species are recorded for the first time from Brazil: O. circaverna Kelley, 1983, O. longissima Flint, 1974, O. macrosterna Flint, 1974, O. peruviana Harris & Davenport, 1999, O. picita Harris & Davenport, 1999, and O. presilla Harris & Davenport, 1999. Oxyethira tica Holzenthal & Harris, 1992, reported from Minas Gerais, Brazil, is now also recorded from Amazonas.
A new species of the genus Agnaptoria Reitter from Xizang, China (Coleoptera, Tenebrionidae: Blaptini)
Authors: REN GUO-DONG , LIU HAO-YU
Published: July 2019

The genus Agnaptoria Reitter (1887) from China is studied and a new species is reported, A. nigripes sp. nov. (CHINA, Xizang). The formerly unknown male of A. amdoensis Medvedev (2006) is described for the first time; also, the poorly known male of A. markama Shi & Ren (2005) is redescribed.
A taxonomic revision of the genus Drassodex Murphy, 2007 (Araneae: Gnaphosidae)
Authors: HERVÉ CHRISTOPHE , ROBERTS MICHAEL J. , MURPHY JOHN A.
Published: July 2019

The worldwide ground-spider genus Drassodes is among the most diverse in the family Gnaphosidae, but it currently includes many species which do not show characters typical of Drassodes sensu stricto. The species belonging to the hypocrita-group of Simon, recently transferred to the genus Drassodex, are revised and redescribed: Drassodex hispanus, D. heeri, D. hypocrita, D. fritillifer, D. cervinus and D. validior. Lectotypes are here designated for D. cervinus and D. validior. The subspecies D. hispanus lesserti is also included and elevated to species rank. Three new species are described, D. granja sp. nov. from Spain, D. drescoi sp. nov. and D. simoni sp. nov. from the western part of the Alps. Representatives of Drassodex mainly occur in mountain systems in western Europe.
A new species of hill stream loach (Teleostei: Balitoridae) from Central Kalimantan, with redescriptions of Homaloptera tateregani Popta and Homaloptera stephensoni Hora
Authors: HUI TAN HEOK
Published: July 2019

Homaloptera batek, new species, is a riffle specialist differentiated by its unique colour pattern for a species of Homaloptera, consisting of a series of round blotches interspaced by smaller blotches in large individuals. The poorly known species Homaloptera tateregani and H. stephensoni are redescribed; the former is restricted to the upper Mahakam basin in East Kalimantan, whereas the latter is distributed throughout Borneo. The status of the genus Pseudohomaloptera Silas is also considered.
The Elachistinae (Lepidoptera: Elachistidae) of Kenya with descriptions of eight new species
Authors: SRUOGA VIRGINIJUS , DE PRINS JURATE
Published: July 2019

No Elachistinae have ever been recorded from Kenya. Here, we present nine taxa, including the descriptions of eight new species: Elachista brevis sp. n., E. kakamegensis sp. n., E. longispina sp. n., E. planca sp. n., Perittia falciferella sp. n., P. gnoma sp. n., P. spatulata sp. n., and P. tantilla sp. n. The new species are diagnosed and illustrated with drawings and photographs of the adults and genitalia. Elachista chelonitis Meyrick is reported for the first time from Kenya. The genus Cleroptila Meyrick is considered to be a synonym of Elachista Treitschke (syn. n.) and Gautengia Kemal & Koçak a synonym of Perittia Stainton (syn. n.). A checklist of Afrotropical Elachistinae is presented.
Phalacrotophora species (Diptera: Phoridae) with four subequal scutellar setae and notes on the other European species
Authors: LENGYEL GÁBOR DÁNIEL
Published: July 2019

The unknown male of Phalacrotophora spectabilis Schmitz, 1925 and the unknown female of Phalacrotophora pictofasciata Schmitz, 1919 are described. New data on the Hungarian Phalacrotophora species are given. P. pictofasciata and P. spectabilis are new to the fauna of Hungary. A revised key with figures for the European species is presented.
A new dwarf cichlid genus and species (Teleostei, Cichlidae) from Guinea, West Africa
Authors: LAMBOJ ANTON
Published: July 2019

Enigmatochromis lucanusi, a new cichlid genus and species, is described from Guinea (West Africa). It is a member of the chromidotilapiine cichlid clade, and differs from other genera within the group in a combination of morphological characters and coloration patterns; e.g., twelve circumpeduncular scales; three tubular infraorbital bones in addition to the lachrymal bone; upper lateral-line separated from the dorsal-fin base; first ray of pelvic fin in adult females of equal length or longer than second ray; sexual dimorphism well developed; small juveniles with 3–4 rows of irregular dark dots on body; and breeding coloration of females.
Three new water mite species (Acari: Hydrachnidia) from Golestan Province (NE Iran)
Authors: PESIC VLADIMIR , JABALEH ISA , SABOORI ALIREZA , ASKARIANZADEH ALIREZA , ASADI MAHDIEH
Published: July 2019

Three new water mite species (Acari: Hydrachnidia) are described from rivers in the Golestan Province (NE Iran), Atractides gorgani sp. nov., A. hyrcaniensis sp. nov. and Axonopsis iranica sp. nov.
Review of Pachymeroceroides genus with the description of a new species (Hemiptera: Heteroptera: Miridae: Bryocorinae)
Authors: UCELI LORENA FERRARI , FERREIRA PAULO SÉRGIO FIUZA , PIROVANI VICTOR DIAS
Published: July 2019

A review of the genus Pachymeroceroides is presented, together with a diagnosis, redescription of the genus and of P. bromeliae (Carvalho 1946), and a description of a new species, P. novabadensis. The authors present notes about host plants and geographic distributions. A picture of habitus and illustrations of genitalic characters are included.
A taxonomic revision of the Oriental species of Thaumatodryinus Perkins, with descriptions of two new species from P. R. China (Hymenoptera: Dryinidae)
Authors: XU ZAIFU , OLMI MASSIMO , HE JUNHUA
Published: July 2019

The Oriental species of Thaumatodryinus Perkins are revised. Two new species, Thaumatodryinus zhejiangensis and hainanensis, are described from the People’s Republic of China, respectively from Zhejiang Province, Qingliangfeng, and Hainan Province, Jianfengling. A new key to the Oriental Thaumatodryinus is presented.
A new species of the bee genus Centris from Peru (Hymenoptera: Apidae)
Authors: ZANELLA FERNANDO CÉSAR VIEIRA , VIVALLO FELIPE
Published: July 2019

Centris (Paracentris) Cameron is one of the more diverse subgenera within the bee genus Centris (Moure et al. 2007), being broadly distributed in the Neotropical Region, and showing an amphitropical distribution pattern (Michener 1979). The sixteen South American species of Centris (Paracentris) (Zanella 2002; Moure et al. 2007) occur in different biomes of the continent; such as low altitudes and valleys of Central Chile and Argentina (Roig-Alsina 2000; Vivallo et al. 2003), high altitudes of the Andes (they are specially diverse in this region) and with a few species in the low mountain chains and plains of Eastern Brazil (Zanella 2002). The subgenus was recently revised by Zanella (2002) and a new species from Central Peru is described here, which augments that revision.
Discrimination between two sibling species of Acroperus (Baird, 1843) from the Palearctic (Cladocera: Anomopoda: Chydoridae)
Authors: SINEV ARTEM Y.
Published: July 2019

Morphology and differential diagnosis of two common Eurasian but frequently confused Eurasian cladocerans, Acroperus harpae (Baird, 1834) and A. angustatus Sars, 1863, was investigated. Validity of both species is confirmed. A significant intraspecific variation in body shapes, unusual for species of the family Chydoridae, is present in females of both species. This “traditional” character is unreliable as diagnostic feature. Prominent differences between two species are revealed in antennal morphology, used for identification of all instars of males and females. Detailed morphology of males, postembryonal development of both males and females was studied in details for the first time. Our data suggest that two other European Acroperus taxa, A. neglectus Lilljeborg, 1900 and A. alonoides Hudendorff, 1876, are junior synonyms.
Orientocreadium elegans n. sp. and Orientocreadium pseudobagri Yamaguti (Digenea: Orientocreadiidae), from freshwater fish of the Primorsky region (southern far east, Russia) with a description of their life cycles
Authors: BESPROZVANNYKH VLADIMIR V. , ERMOLENKO ALEXEY V. , DEVENEY MARTY R
Published: July 2019

Until recently only one species from the genus Orientocreadium was recorded from the southern part of the Primorye Region, far eastern Russia: O. pseudobagri Yamaguti. A new species, Orientocreadium elegans n. sp., was found recently in the yellow catfish, Pelteobagrus fulvidraco in rivers running into Khanka Lake and in the Arsenjevka River (part of the Ussuri River basin). It is distinguished from other species of Orientocreadium by possessing a body that is longer and narrower than Orientocreadium pseudobagri and shorter and narrower than Orientocreadium siluri and Orientocreadium chaenogobii. The suckers of O. elegans n. sp. are smaller than those of all other species of Orientocreadium and the pharynx is smaller than those of O. siluri and O. chaenogobii. Orientocreadium elegans n. sp. has spines on the cirrus and inside the metraterm and has the ovary in the posterior half of the body, differentiating it from O. siluri. Orientocreadiium elegans n. sp. has a cirrus sac that lies on the median line of the body dorsal to the ventral sucker, whereas the cirrus sac of O. pseudobagri passes laterally around the ventral sucker. Both trematode species use Lymnaea spp. snails as their first intermediate host, and tadpoles, freshwater fish and snails as the second intermediate host. The following fish have been recorded as definitive hosts in this region: the Amur sleeper, Perccottus glehni and P. fulvidraco for O. pseudobagri, and P. fulvidraco for O. elegans n. sp.
The tetranychid mites (Acari: Tetranychidae) of Kenya and a redescription of the species Peltanobia erasmusi Meyer (Acari: Tetranychidae) based on males
Authors: TOROITICH FAITH J. , UECKERMANN EDWARD A. , THERON PIETER D. , KNAPP MARKUS
Published: July 2019

This paper reports 18 tetranychid mite species (Acari: Tetranychidae) from various plant hosts in Kenya. Four species of these belong to the subfamily Bryobiinae and the other 14 belong to the subfamily Tetranychinae. Eight of the mite species identified belong to the genera Bryobia, Petrobia, Peltanobia, Paraplonobia, Duplanychus, Eutetranychus and Mixonychus and are being reported for the first time in Kenya while the other ten had already been reported before. The paper provides a list of these species and their brief descriptions as well as a redescription of Peltanobia erasmusi Meyer (Acari: Tetranychidae) to include male characters that were not included in the original description.
Revision of the genus Pseudonicsara Karny, 1912 (Orthoptera: Tettigoniidae: Conocephalinae: Agraeciini) - Revision of the Indo-Australian Conocephalinae, part 2
Authors: INGRISCH SIGFRID
Published: July 2019

The genus Pseudonicsara Karny, 1912 is fully revised. The characteristic, in cross-section triangular fore tibia together with the short male pronotum leaving the stridulatory apparatus uncovered are the main diagnostic characters. A key to the species is given. Three subgenera are recognised: Pseudonicsara Karny, 1912 with 35 species and 1 subspecies, Cercana subgen. n. with 15 species and Wasiorana subgen. n. with 3 species. P. aeruginifrons (Karny, 1912) becomes a new synonym of P. pallidifrons (Brunner, 1898), and Agraecia ornata Karny, 1907 a new synonym of P. semicruciata (Brunner, 1898). 46 species and 1 subspecies are described as new: P. (P.) abbreviata sp. n., P. (P.) apicata sp. n., P. (P.) apingan sp. n., P. (P.) april sp. n., P. (P.) arcuata sp. n., P. (P.) bitriangulata sp. n., P. (P.) buergersi sp. n., P. (P.) cervus sp. n., P. (P.) clavus sp. n., P. (P.) clavus carinata ssp. n., P. (P.) concha sp. n., P. (P.) dilatata sp. n., P. (P.) divitata sp. n., P. (P.) excisa sp. n., P. (P.) finister sp. n., P. (P.) forceps sp. n., P. (P.) karimui sp. n., P. (P.) lehm sp. n., P. (P.) lina sp. n., P. (P.) maritima sp. n., P. (P.) minuta sp. n., P. (P.) missim sp. n., P. (P.) nomo sp. n., P. (P.) pugio sp. n., P. (P.) spatula sp. n., P. (P.) stylata sp. n., P. (P.) uncinata sp. n., P. (P.) undulata sp. n., P. (P.) wanuma sp. n., P. (P.) wau sp. n., P. (P.) wum sp. n., P. (P.) zugi sp. n., P. (Cercana) bomberi sp. n., P. (Cercana) digitata sp. n., P. (Cercana) dodinga sp. n., P. (Cercana) furcata sp. n., P. (Cercana) halmahera sp. n., P. (Cercana) hum sp. n., P. (Cercana) nana sp. n., P. (Cercana) sinuata sp. n., P. (Cercana) siwi sp. n., P. (Cercana) spinibranchis sp. n., P. (Cercana) stridulans sp. n., P. (Cercana) taliabu sp. n., P. (Cercana) wanigela sp. n., P. (Wasiorana) alces sp. n., and P. (Wasiorana) curvata sp. n. Three species are removed from the genus: P. lobaspoides (Karny, 1907) and P. ornata (Brunner v. W., 1898) are transferred to Axylus Stål, 1877, and P. nigrifrons C.Willemse, 1923 is provisionally left in Salomona Blanchard, 1853, the genus in which it was originally described. Species of the subgenus Pseudonicsara are so far with certainty only known from New Guinea, those of Wasiorana were all found in North-Western New Guinea, and those of Cercana in West and South New Guinea and on the Maluku Islands (East Wallacea). The species often occur allopatric but of Pseudonicsara s.str. up to three species were found in the same locality.
Revision of Milichiella Giglio-Tos (Diptera, Milichiidae)
Authors: BRAKE IRINA
Published: July 2019

The species of Milichiella Giglio-Tos are revised and assigned to species groups revealed by a phylogenetic analysis. 69 new species are described: Milichiella abditoargentea, M. acantha, M. aeroplana, M. aldabrae, M. angolae, M. anterogrisea, M. argenteidorsa, M. argentinae, M. asiatica, M. badia, M. bella, M. bermaguiensis, M. boliviana, M. booloombae, M. breviarista, M. brevirostris, M. bruneiensis, M. cavernae, M. chilensis, M. chocolata, M. christmas, M. cochiseae, M. conventa, M. cooloolae, M. dominicae, M. faviformis, M. flavilunulae, M. flaviventris, M. formosae, M. fusciventris, M. griseomacula, M. inbio, M. jamaicensis, M. laselvae, M. lasuizae, M. longirostris, M. maculatiradii, M. madagascarensis, M. mathisi, M. metallica, M. mexicana, M. mojingae, M. mollis, M. multisetae, M. novateutoniae, M. opuntiae, M. pachycerei, M. peyotei, M. plaumanni, M. proclinata, M. pseudopuntiae, M. punctata, M. quintargentea, M. rufa, M. rugosistyla, M. rutila, M. santacatalinae, M. sculpta, M. sterkstrooma, M. striata, M. triangula, M. trisetae, M. turrialbae, M. ugandae, M. variata, M. villarricae, M. virginae, M. weejasperensis and M. zaiziksensis. Milichia aethiops Malloch is combined with Milichiella, the genus Ulia Becker is synonymized with Milichiella, five species within Milichiella are synonymized and 19 lectotypes are designated.
Revision of the genus Zeugophora (Coleoptera, Megalopodidae, Zeugophorinae) in Japan
Authors: TAKEMOTO TAKUYA
Published: July 2019

Japanese species of the genus Zeugophora Kunze, 1818 (Coleoptera, Megalopodidae, Zeugophorinae) are revised. In this publication, Zeugophora annulata (Baly, 1873), Z. unifasciata (Jacoby, 1885), Z. hozumii Chûjô, 1953, Z. japonica Chûjô, 1951, Z. varipes (Jacoby, 1885), Z. chujoi Ohno, 1961, Z. flavonotata (Chûjô, 1935), and Z. gracilis unicolor Chûjô, 1958 are redescribed, with detailed illustrations of the male and female genitalia. Additionally, Z. nigricollis (Jacoby, 1885) is restored to a valid species from junior synonymy with Z. bicolor (Kraatz, 1879), and Z. cupka sp. nov., is described as a new species.
Impacts of the East Asian Winter Monsoon and Local Sea Surface Temperature on Heavy Snowfall over the Yeongdong Region
Authors: Kim Jineun , Yoon Donghyuck , Cha Dong-Hyun , Choi Yonghan , Kim Joowan , Son Seok-Woo
Published: July 2019

This research investigates the impact of local sea surface temperature (SST) on the 2-month (January and February) accumulated snowfall over the Yeongdong (YD) region. The YD region is strongly affected by synoptic-scale factors such as the East Asian winter monsoon (EAWM). The relationships of snowfall over the YD region to the EAWM and local SST are examined based on observational analyses and sensitivity experiments using a regional climate model. In the sensitivity experiments, local SST is replaced with the 33-yr mean winter SST (1982–2014). The observational analysis shows that both the synoptic environment and local SST are important factors for the occurrence of anomalous heavy snowfall over the YD region. The favorable synoptic environments can be characterized by eastward expansion of the Siberian high over Manchuria and corresponding enhancement of easterly anomalies over the YD region. These conditions are more frequently observed during the weak EAWM years than during the strong EAWM. Furthermore, warm SST over the East Sea contributes to heavy snowfall over the YD region by providing heat and moisture in the lower troposphere, which are important sources of energy for the formation of heavy snowfall. Warm SST anomalies over the East Sea enhance low-level moisture convergence over the YD region, while cold SST anomalies lead to reduced moisture convergence. Sensitivity experiments indicate that local SST can significantly affect snowfall amount over the YD region when the synoptic environments are favorable. However, without these synoptic conditions (expansion of the Siberian high and easterly inflow), the impact of local SST on the snowfall over the YD region is not significant.
The Feeling Economy: Managing in the Next Generation of Artificial Intelligence (AI)
Authors: Huang Ming-Hui , Rust Roland , Maksimovic Vojislav
Published: July 2019

The capability of AI is currently expanding beyond mechanical and repetitive to analytical and thinking. A “Feeling Economy” is emerging, in which AI performs many of the analytical and thinking tasks, and human workers gravitate more toward interpersonal and empathetic tasks. Although these people-focused tasks have always been important to jobs, they are now becoming more important to an unprecedented degree. To manage more effectively in the Feeling Economy, managers must adapt the nature of jobs to compensate for the fact that many of the analytical and thinking tasks are increasingly being performed by AI, and, thus, human workers must place increased emphasis on the empathetic and emotional dimensions of their work.