bluuebunny/crossref_metadata_2025 huggingface dataset:
Haus des Volkes in Probstzella: Der Rote Itting und politisch-kulturelle Erwachsenenbildung in einem Bauhausgebäude
Authors: Bernd Käpplinger
Published: November 2023

Zwischen 1925 und 1927 entsteht das größte Bauhaus-Ensemble in Thüringen, das Haus des Volkes in Probstzella. Bernd Käpplinger erläutert in seinem Beitrag, wie die Entstehung und die Umsetzung dieses Gebäudes, das von dem sozialdemokratischen Unternehmer Franz Itting – der Rote Itting – initiiert wurde, eine außerordentliche Verbindung von Industrie-, Sozial- und Baureform sowie Erwachsenenbildung darstellt.
Wer wird gefördert?
Authors: Proskawetz Franziska Sophie
Published: November 2023

Soziale Herkunft entscheidet in Deutschland über den Bildungserfolg. Die ungleiche Verteilung von Bildungschancen zeigt sich auch im Bereich der Begabtenförderung: Obwohl Begabung und Intelligenz in der Gesellschaft normalverteilt sind, sind Schüler:innen aus weniger privilegierten Verhältnissen in Stipendienprogrammen und Begabtenförderungswerken unterrepräsentiert. Ursachen dafür lassen sich bei Lehrkräften ausfindig machen, die Schüler:innen für Förderprogramme nominieren. Die Studie analysiert anhand des Stipendienprogramms RuhrTalente, wie Lehrkräfte Stipendienwürdigkeit konstruieren. Aus den Ergebnissen lassen sich Maßnahmen ableiten, die zu einem langfristigen Abbau von Bildungsungerechtigkeit beitragen können.
Harmonization of Islamic Legal Institutions and Customary Law in Marriage Dispensation Cases at The Panyabungan Religious Court
Authors: Sebyar Muhamad Hasan
Published: November 2023

Harmonization between customary law and Islamic law (fiqh) has long occurred in our homeland. This study aims to illustrate the harmonization between Islamic legal institutions and customary institutions. This research is an empirical legal research, empirical legal research is research whose object of research is the practice of legal events or occurrences. The approach used in this study is a socio-legal approach, that used to analyze the social interactions between the Panyabungan Religious Court and customary institutions in implementing age dispensation. The results of this study show that this harmonization had run well between Islamic legal institutions and customary institutions. There is harmonization of existing norms or rules that apply in society. In substance making Islam more widespread in society and the state, from the understanding of classical jurisprudence to other legal products namely qadla, Islamic Law in substance continued to develop and acquire all regulations towards the rule of Islamic law as a whole. The similarity of certain functions within the customary law system, the Islamic legal system, and the national legal system according to the scope of their duties determines the extent to which harmonization occurs. The method of harmonization between Islamic law and customary law can be achieved in three ways, namely first; Harmonization of understanding, Second; Harmonization is carried out actively,Third; Passive harmonization.
Airbase Compatibility with Spatial Planning: A Case Study of Airbase Waterkloof (South Africa)
Authors: Brand Andre
Published: November 2023

The primary roles of the South African National Defence Force (SANDF) are to protect and advance South Africa’s strategic interests through the promotion of security and stability, and to provide military capabilities to defend South Africa and its national interests. The South African Air Force (SAAF), as an entity of the SANDF, is mandated to defend South Africa’s airspace from unfriendly or unauthorised incursions. Noise emission and aviation safety, as products of air traffic movement, generate distinct spatial footprints. The productivity of an airbase can be negated if the unity between these footprints and the immediate built environment is not appropriately directed and managed. This can ultimately compromise an airbase’s mission readiness. This paper, with Airbase Waterkloof (which represents the largest military operational support base within South Africa) as a case study, investigates the degree of unity that exists between an airbase and its surrounding urban environment. The paper specifically focuses on the spatial footprints generated by noise emission and aviation safety as products of air traffic movement, and the legislative measures that prevail between the SANDF, SAAF, and National and Local Governments. The findings reflect that legislative measures are clearly defined, and jurisdiction is distinctively delineated. However, the integration and mitigation of matters around noise and aviation safety are perpetrated through a process of internal policies and regulations and public participation, which is not adequate when striving to attain harmony between an airbase and the surrounding built environment.
Evaluation of hybrid apple seedlings according to the main economic and biological characteristics in the Orenburg region
Authors: Merezhko Ol'ga , Aminova Evgeniya
Published: November 2023

Abstract. The aim is to evaluate hybrid apple seedlings according to the main economic and biological characteristics in the conditions of the Orenburg region. Methods. The studies were carried out from 2002 to 2022 in the Orenburg branch of the Federal State Budget Scientific Institution of the Federal Scientific Center for Horticulture. The objects of research were 10 hybrid families of apple trees selected by the Federal State Budget Scientific Institution of the Federal Scientific Center for Horticulture. The main observations and records on the main economic and biological characteristics were carried out according to the methodology “Program and methodology for the selection of fruit, berry and nut crops”, “Program and methodology for the study of variety of fruit, berry and nut crops”, statistical processing of experimental data was carried out by the method of two-factor analysis of variance, where A is the variety, B is the year. The scientific novelty lies in the fact that as a result of the conducted research, promising hybrid forms with a complex of economically valuable traits, with a high potential for productivity and large-fruiting in the conditions of the Orenburg region have been identified. Results. The genetic collection of the Orenburg branch of the Federal State Budgetary Scientific Institution of the Federal Scientific Center for Horticulture serves as a fundamental basis for breeding work, which makes it possible to intensify the creation of adaptive, highly productive apple varieties. It has been established that the majority of hybrid apple seedlings have high winter hardiness. Weak freezing (0.2–0.5 points) characterizes hybrids of crossbreeding combinations, such as BratChud × Simvol, Kovrovoe × Anis Sverdlovskiy. Phytosanitary monitoring carried out on the site of hybrid apple seedlings showed that over the years of the study, weather conditions did not allow the development of diseases in the apple tree. On average, fruits in the offspring were 1-1, 1-5, 1-6, 1-7, 1-8, 1-9, 1-10 (140.0 ... 150.0 g). The greatest productivity was formed by hybrids of combinations of crossing BratChud × Simvol (24.6 kg/tree), Orskoe × Prizemlennoe (24.0 kg/tree) and Arkaim × Podarok Orenburzh’yu (24.2 kg/tree).
Pengaruh Permainan What’s Missing terhadap Kosa Kata Bahasa Inggris Anak
Authors: Pebrianti Lestari
Published: November 2023

Penelitian ini dilatarbelakangi oleh rendahnya kosa kata Bahasa inggris  anak yang disebabkan oleh penggunaan media, metode dan pendekatan pembelajaran kurang bervariasi sehingga tujuan dari penelitian ini untuk mengetahui pengaruh permainan Iwhat’s missing terhadap pengenalan kosa kata bahasa inggris anak di Taman Kanak-kanak Islam Bakti 77 Ampang Kuranji Dhamasraya. Penelitian ini menggunakan pendekatan kuantitatif yang berbentuk quasi ekperimental dengan jenis one group pretest-postest design yang bertujuan untuk mengetahui pengaruh variable bebas dari permainan what’s missing terhadap variable terikat yaitu kosa kata bahasa inggris anak setelah digunakan. Teknik pengumpulan data digunakan tes lisan dan tes perbuatan, berupa pernyataan sebanyak 6 butir dan teknik analisis data menggunakan uji normalitas, uji hipotesis dan uji normalized gain score dengan SPSS 26 for mindows. Hasil penelitian menunjukkan bahwa data berdistribusi normal. Selanjutnya berdasarkan paired sample t-test (2-trailed) adalah sebesar 0,000<0,05 sehingga dapat disimpulkan bahwa permainan what’s missingberpengaruhterhadap pengenalan kosa kata bahasa inggris anak di Taman Kanak-kanak Islam Bakti 77 Ampang Kuranji Dhamasraya.
PENGARUH METODE EKSPERIMEN TERHADAP KEMAMPUAN SAINS ANAK KELOMPOK B USIA 5-6 TAHUN DI TK MARUZAN MAKASSAR
Authors: Susanti Hadra , Parwoto Parwoto , Wahyuni Asti Sri
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh kegiatan eksperimen terhadap kemampuan sains anak usia 5-6 tahun di TK Maruzan Makassar. Berdasarkan pengamatan kenyataan di lapangan terdapat permasalahan yaitu rendahnya kemampuan sains anak yang masih kurang dikarenakan metode pembelajarannya masih bersifat konvensional yang artinya bersifat monoton. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif dengan jenis penelitian Quasi Eksperimental Design dengan desain penelitian yaitu Nonequivalent control group desain. Populasi dalam penelitian ini adalah kelompok B di Tk Maruzan Makassar. Pengambilan sampel dalam penelitian ini adalah sampling jenuh. Sampel dalam penelitian ini adalah 12 anak, 6 anak sebagai kelompok eksperimen dan 6 anak sebagai kelompok kontrol. Teknik pengumpulan data yang digunakan adalah analisis statistik deskriptif dan analisis statistik nonparametrik. Hasil analisis data diperoleh Asym (2-tailed) =0,027 < 0,05 H1 diterima dan H0 ditolak, artinya kemampuan sains anak pada kelompok eksperimen mengalami perkembangan yang signifikan dibandingkan kelompok kontrol. Ini menunjukkan bahwa kegiatan eksperimen memberikan pengaruh terhadap pengaruh terhadap kemampuan sains anak udia 5-6 tahun di TK Maruzan Makassar.
Karl Marx’ın Çatışmacı Yaklaşımı ile Kemal Tahir-Baykan Sezer Çizgisinin Karşılaştırılması
Authors: ÇETİN Berkay , GÜNGÖR ERGAN Nevin
Published: November 2023

Çatışmacı yaklaşım, genel olarak sosyal bilimler, özel olarak da sosyoloji literatüründe oldukça tartışılmıştır. Çatışmacı yaklaşım içerisinde birçok farklı isim ve gelenek bulunmaktadır. Bu çalışmada ise özellikle Baykan Sezer’in, Kemal Tahir’in düşüncelerinden etkilenerek sosyoloji literatürüne kazandırdığı Doğu-Batı Çatışması Teorisi ile Karl Marx’ın çatışmacı yaklaşımı tartışmaya tabi tutulmuştur. Çalışmada, yorumsamacı geleneğe dayalı olarak doküman analizi tekniğinden yararlanılmıştır. Bu kapsamda birincil ve ikincil kaynaklar incelenmiştir. Baykan Sezer tarafından yayımlanmaya başlanan ve günümüzde yayına devam eden Sosyoloji Yıllıkları, temel kaynak olarak dikkate alınmıştır. Çalışma kapsamında, öncelikle Karl Marx’ın çatışmacı yaklaşımı kısaca özetlenmiş, sonrasında Kemal Tahir-Baykan Sezer çizgisindeki belirgin temalar ele alınmıştır. Söz konusu temalar; tarihin gerekliliği; özgünlük vurgusu; Türk insanının çıkarlarını gözetmek; Batı düşünü ve bilimi karşısındaki konum başlıkları etrafında tartışılmıştır. Sonrasında ise Doğu-Batı çatışmasının tarihinde belli başlı kırılma noktaları özetlenmiştir. Doğu-Batı çatışmasının tarihine ilişkin olarak özellikle Sosyoloji Yıllıkları’ndaki çalışmalar dikkate alınmıştır. Çalışma sonucunda Kemal Tahir-Baykan Sezer çizgisindeki çatışmacı yaklaşım Marx’ın yaklaşımı ile kıyaslanmıştır. Yapılan kıyaslama neticesinde, söz konusu yaklaşımlar arasında benzerliklerin olduğu gibi farklılıkların da olduğu tespit edilmiştir. Özellikle çatışmanın varlığı, iki yaklaşımda da mevcuttur. Ayrıca hem Karl Marx hem de Kemal Tahir ve Baykan Sezer tarafından hâkim/egemen bilim anlayışına yönelik eleştiri getirilmiştir. Kemal Tahir-Baykan Sezer çizgisinde ortaya çıkan farklılıkların ise bilhassa Türk toplumu ve tarihinin (genel itibarıyla da Doğu’nun) Batılı kavram ve şemalarla birebir örtüşmemesi noktasında görünürlük kazandığı gözlemlenmiştir.
A Jungian Analysis of Sacraments in John Donne’s 'Holy Sonnets'
Authors: KURTULUŞ Melih
Published: November 2023

This article aims to analyse three poems in John Donne’s religious sonnet collection titled Holy Sonnets within the context of the Jungian concept of the individuation process. In this respect, the article presents two related arguments. First, it is contended that the poetic personae of the selected poems, namely “Thou hast made me,” “Oh my blacke Soule!,” and “Batter my heart,” suffer from neurosis because of their reluctance and inability to perform the two tasks of the individuation process. The process put forward by Carl Gustav Jung requires an individual to both separate herself/himself from societal demands and integrate the unconscious part of her/his psyche with the conscious one. In the case of the selected poems’ speakers, their unconscious sides are constituted by their carnal desires which they wish to suppress to the point of extinction. Feeling inadequate to suppress their bodily passions, they ask their Creator to intervene in the process. However, neither God responds to their prayers, nor their undesirable selves disappear from their conscious minds. Thus, the poetic speakers oscillate painfully between their carnal and spiritual selves, indicating that they suffer from neurosis. God’s silence in this process stems from the speaker’s rejection to utilize sacraments as mediatory objects. In this respect, it is argued that the speakers are influenced by Protestant iconophobia. Therefore, the second argument suggests that the selected poems showcase that rejecting sacraments’ mediatory function halts one’s attempt to bridge the gap between the conscious and the unconscious parts of the psyche which is the main aim of the individuation process.
Changes in the quality of sour milk curds with candied fruit and dry licorice root during storage
Authors: Nagovska V. O. , Bilyk O. Ya. , Slyvka N. B. , Mykhaylytska O. R.
Published: November 2023

In recent years, there has been a scientific interest in healthy nutrition, namely the development and consumption of products. which have a beneficial effect on the human body and can reduce the risk of various diseases. The work aimed to investigate the change in the quality of sour milk curds with candied fruit and dry licorice root during storage. The research was carried out at the Ivano-Frankivsk DP, as well as in the laboratory of the Department of Technology of Milk and Dairy Products of the Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv. When determining the titrated acidity in curds with candied fruit without licorice root during the storage period at a temperature of 4 ± 2 °C, it increases from 200 °T to 230 °T. In sour milk curds with candied fruit and dry licorice root, the titrated acidity on the first day of storage was 220 °C T, and on the fifth day – 230 °T. Since, according to the standard, fermented milk curds with candied fruit can be stored for no more than 3 days, based on the conducted research, we conclude that the newly made curds are entirely safe for consumption during the above period. Analyzing the microbiological indicators of newly created sour milk curds with candied fruit and dry licorice root, we can conclude that this product is harmless to health, as its sanitary condition meets the standard's requirements. Thus, using dry licorice root in producing sour milk curds with candied fruit as a non-dairy additive does not impair the microbiological indicators of this type of curd.
Cardiometabolic Risk Assessment through Comprehensive Screening for Early Detection
Authors: Andra Cut Aryfa , Hasan Refli , Khairul Andi , Tamba Ratna Mariana , Putra Muhammad Hafiz Mahruzza
Published: November 2023

Background: The development of cardiovascular disease (CVD) is influenced by many risk factors, such as tobacco use, an unhealthy diet, and physical inactivity, that could result in obesity, hypertension, dyslipidemia, and diabetes mellitus. Continuing exposure to these risk factors can be prevented by routine screening for populations without any clinical symptoms. This study was conducted to obtain data on cardiometabolic profiles of people who participated in the Community Service Program of the Department of Cardiology and Vascular Disease, University of Sumatera Utara.
Method: This research was a descriptive study with a cross-sectional research design. The study aims to screen for the cardiometabolic profile in the people of Tebing Tinggi City.  Cardiovascular risk factors were obtained from interviewing the participants and on-the-spot examination with validated measurement tools. All data were processed and analyzed statistically using SPSS ver.26. Categorical variables are presented with frequency (n) and percentage (%). Numeric variables are presented with mean and standard deviation (SD) values for normally distributed data. As for the normal non-distributed data numerical variables are presented with the middle value (median) and the interquartile range.
Results: All subjects in this study (n= 102) are 39 male and 63 female. Most participants were in the 4th to 5th decade, with normal heart rates and normal sinus rhythm. Most female participants had a low risk for obstructive sleep apnea (OSA) and the male had intermediate risk. Most participants had normal random blood sugar and total cholesterol but mostly had obesity. Near 20-30% of participants were grade I and II systolic hypertensives but normally had diastolic blood pressure.
Conclusion: In this study, most of the cardiometabolic risks of patients in the Community Service program were obesity, followed by hypertension.
DIGITALISATION OF FINANCIAL MARKETS, CURRENT ISSUES AND CHALLENGES
Authors:   Taras Shevchenko National University of Kyiv, Babych Oleksandr
Published: November 2023

The digitalization of financial markets stands as an emblematic phenomenon in the contemporary financial landscape, redefining the way financial instruments are traded, managed, and accessed. Digitization is considered through the prism of its technological manifestations and solutions presented on financial markets, and increasingly implemented by counterparties that operate on them. This article delves into the relevance of this transformative process and its impact on global finance. Digitalization, encompassing technologies like blockchain, algorithmic trading, and decentralized finance (DeFi), has engendered a paradigm shift in financial markets. These encompass not only heightened operational efficiency and substantial cost reductions but also the pivotal enhancement of customer interactions and engagement. The digitalization of financial markets is fundamentally altering how financial services are offered, accessed, and experienced, propelling the sector towards unprecedented efficiencies. This transformation has brought forth a host of challenges and complexities that are critical to comprehend. Regulatory frameworks face the daunting task of evolving to accommodate the dynamic landscape of digital finance while preserving market integrity. The evolving cybersecurity landscape poses new threats and vulnerabilities, demanding advanced security measures to mitigate risks. Moreover, investor protection assumes heightened importance as decentralized financial services redefine traditional safeguards. In this quest for comprehensive insights, the article illuminates pragmatic pathways to address these challenges. The implementation of cutting-edge Fintech solutions emerges as a crucial strategy for financial institutions seeking resilience and growth in an era marked by digital disruption. Embracing innovation, adapting regulatory frameworks, and fortifying cybersecurity measures are essential steps towards navigating the currents of change and harnessing the full potential of digitalization while safeguarding the integrity of financial markets. This article invites readers to explore the pertinent issues and complexities intertwined with the digitalization of financial markets. By understanding the challenges, financial institutions can navigate this transformative landscape, fostering a resilient and sustainable future for global finance.
LOGISTICS COMPONENT OF INTERNATIONAL TRADE: VALUE AND ORDER OF SECUREMENT
Authors:   Admiral Makarov National University of Shipbuilding, Marushchak Svitlana , Pochernina Nataliia ,   Dmytro Motornyi Tavria State Agrotechnological University, Golomsha Nataliia ,   National University of Life and Environmental Sciences of Ukraine
Published: November 2023

Every year, the logistics industry is increasingly strengthening its position as an integral element of international trade. Under the influence of globalization, international borders are being erased, which also increases the importance of the logistics sector and turns it into one of the most dynamic in the world. Logistics services are gaining even more relevance, as countries strive to occupy leading positions in the market, and in the conditions of the complication and progression of production processes, this is not possible without logistics. The scientific article defines the impact of logistics support on the order of conducting international trade, and establishes the place of logistics in it. The processes that influenced the increase in the need for effective logistics support were investigated, and the distinctive features between logistics support at the international and national level were established. An indicator based on which companies can draw conclusions about the degree of development of logistics in a particular country is presented, the procedure for its calculation and interpretation of the obtained results is determined. The Logistics Efficiency Index was evaluated in 2016, 2018, and 2023, with the determination of trends in the ranking leaders based on the value of this index. The value of this index for Ukraine was analyzed, with the establishment of relationships between the obtained value and the events that caused it. The components of logistical support of international trade are reflected: regulatory, organizational, infrastructural, informational, financial-economic, scientific-methodical, personnel support. Each of them is detailed. The importance of the principle of intermodality for logistics support is determined. The impact of quarantine restrictions and the war in Ukraine on permanent logistics chains is considered. The procedure for replacing logistics chains with the use of other types of transport is given. Possible options for providing logistical support at the international level in modern conditions were analyzed, and the key role of road and rail transport in this process was determined.
INTRODUCTION OF KNOWLEDGE TRANSFER AND THE CONCEPT OF FLEXICURITY TO IMPROVE STATE REGULATION OF DIGITAL EMPLOYMENT
Authors:   National University ", Lisnichenko Marharyta ,   Zaporizhzhia Polytechnic", Plynokos Dmytro ,   State Scientific Research Institute of Armament and Military Equipment Testing and Certification, Trokhymets Olena ,   Classic Private University
Published: November 2023

The concept of flexicurity is focused on creating a socially oriented labor market model in which flexibility and social protection are key components. These two components interact and contribute to the harmonious development of society, subject to active support from the state and the introduction of the concept of lifelong learning. This approach allows for the creation, development and retention of labor potential in the national market. It should be noted that digital employment is difficult to regulate on a national scale. However, the active development of this type of employment necessitates its monitoring and adaptation of national regulatory instruments. At the same time, digital employment, due to its predominantly remote nature, can be seen as a factor in reducing socio-economic risks in the face of global challenges. In the current environment, the ability not only to produce information and knowledge, but also to organize the transfer of knowledge and technology within the existing state system. The important element of knowledge transfer in Ukraine should be short-term training courses that will ensure the fastest possible adaptation of employees and consumers to the requirements of the modern digitalised economy. The concept of flexicurity is an ideology of state policy in the field of regulation of social and labor relations. The state establishes flexible conditions for hiring and dismissing employees, which provide employers with a freedom for modern restructuring. The introduction of the principles of rational employment, social security and respect for workers' rights, and the development of social dialogue should become the stages of implementing the basic criteria for relation to standard and non-standard forms of employment in the context of digitalisation. One of the elements of knowledge transfer with maximum efficiency and in a short time, based on the concept of flexicurity, is the organisation of short-term training courses in the system of formal and non-formal education.
СТРАТЕГІЗАЦІЯ ПІДВИЩЕННЯ КОНКУРЕНТОСПРОМОЖНОСТІ ПІДПРИЄМСТВА НА РИНКУ ТРАНСПОРТНИХ ПОСЛУГ
Authors: Ареф’єва Олена , Годун Владислав
Published: November 2023

У статті розглянуто аспекти формування та розвитку , підвищення конкурентоспроможності транспортного підприємства. Розроблено модель аналізу конкурентоспроможності підприємств на ринку транспортних послуг. На основі цієї моделі можна проаналізувати рівень конкурентоспроможності транспортного підприємства, визначити сильні та слабкі сторони його розвитку. Описано методи визначення рівня конкурентоспроможності транспортного підприємства. Основними показниками, що формують конкурентоспроможність транспортного підприємства, вважають рухомий склад, виробничо-технічну базу, ціну та якість послуг, можливість проникнення нових конкурентів. Вибрані фактори забезпечення конкурентоспроможності підприємства необхідно проаналізувати за допомогою показників, які їх визначають. Зроблено висновки щодо підвищення конкурентоспроможності підприємства на ринку транспортних послуг
ГУМАНІТАРНА ЛОГІСТИКА ЯК ІНСТРУМЕНТ ТРАНСФОРМАЦІЇ ЛОГІСТИЧНИХ ПОТОКІВ В УМОВАХ ВОЄННОГО ЧАСУ
Authors: Гринів Наталія
Published: November 2023

Стаття присвячена актуальним питанням трансформації логістичних потоків в умовах воєнного часу в Україні. Розглянуто класифікацію товарів гуманітарної допомоги, джерела її отримання, проведено моніторинг логістичних проблем, які виникли в країні з початком повномасштабного вторгнення Росії. Визначено сутність поняття гуманітарної логістики та її основні завдання, описано складнощі роботи з гуманітарними вантажами та запропоновано шляхи запобігання несвоєчасній доставці гуманітарних вантажів. Зазначено, що погано налагоджена координація між різними учасниками логістичного ланцюга призводить до сповільнення відправлення та доставки гуманітарних вантажів. Акцентовано увагу на важливій ролі вітчизняних компаній у процесах доставки гуманітарних вантажів. Окреслено перспективи відновлення логістики у післявоєнний період, що дозволить Україні інтегруватись у європейську систему.
Teszt_2_LP_11.13
Authors: Teszt Author
Published: November 2023

Teszt_2_LP_11.13
Examination of the Effects of Dynamic Speed Limit on Shock Waves with a Simulation Technique
Authors: Nagy Viktor , Kruppa Gergely , Horváth Balázs
Published: November 2023

The aim of motorway networks is to ensure smooth, high volume road traffic. The problem of anomalies in the system has been a long-standing concern for researchers, and with the widespread use of motorway networks a series of studies have been published on the subject. Speed limitation is one of the most important tools of mitigating disturbances. This study is looking for a solution to the problem known as the "shock wave effect". The research is based on a simulation method in a PTV VISSIM environment. The software can be used to examine certain traffic conditions, and then apply dynamic speed limitation based on these conditions. The Built Environment Information Platform (BENIP) is based on the idea that the built environment, the traffic, and the flow of information between them are closely related. The relevance of the study lies in the fact that a point-based notification of speed limits can be used for vehicles – a technology that is available in most cases at the infrastructure level on motorways – thus, improving road capacity and traffic safety.
Tolerability of Chronic Extremely High-dose Use of Methylphenidate. Description of A Clinical Case
Authors: Rosenhagen Marcus C , Vandenberghe Frederik , Faida Judith Gafundu , Wavre Séverine Crettol
Published: November 2023

Methylphenidate (MPH) is frequently employed off-label and at high uncontrolled dosages, even beyond the scope of attention deficit hyperactivity disorder (ADHD) treatment. Intoxications appear to be infrequent and are documented in only a few case reports, with monitoring of plasma concentrations not consistently conducted. In the literature, there are no case reports or studies on the tolerability of high-normal doses of MPH. Here we present a case of prolonged and excessive use of MPH without side effects before the patient was admitted to our psychiatric facility, following the consumption of illegal substances and a brief episode of acute confusion. Surprisingly, after admission, the patient's symptoms improved rapidly, before we substantially reduced the dose.
Exploring the Functional Significance of Lysosomes in Cancer Drug Resistance
Authors:   Department of SmartBio, College of Life and Health Science, Kyungsung University, Busan, Republic of Korea, Jung Jewon
Published: November 2023

Chemotherapy stands as a primary therapeutic approach for tackling a spectrum of malignancies. Nonetheless, the emergence of resistance to chemotherapeutic agents poses a significant hurdle in achieving curative cancer treatments. Lysosomes, recognized as acidic cellular organelles predominantly engaged in intracellular digestion, have garnered increasing attention due to their implications in cancer biology. Notably, their relevance to cancer manifests in several ways: Firstly, the extracellular release of lysosomal enzymes actively promotes tumorigenesis. Secondly, the leakage of lysosomal hydrolases into the cytosol induces apoptosis. Lastly, weak chemotherapeutic bases, upon traversing the lysosomal membrane, become sequestered within lysosomes while adopting a cationic state. This sequestration of drugs within lysosomes diminishes their cytotoxic potential, restricts their availability at target sites, and contributes significantly to the development of drug resistance in cancer. This review comprehensively explores diverse mechanisms underpinning lysosomal drug sequestration and delves into their repercussions on the phenomenon of multidrug resistance in cancer. Furthermore, we delve into strategies aimed at surmounting drug resistance by leveraging lysosomes as subcellular targets, with the aim of reversing drug sequestration and thwarting drug resistance in the context of cancer therapy
A domestic case of pediatric miliary tuberculosis
Authors:   1 Children’s Lung Specialists, Las Vegas, Nevada, USA 2 Department of Pediatrics, School of Medicine, University of Nevada Las Vegas, Las Vegas, Nevada, USA 3 Department of Infectious Disease, Children’s Hospital of Orange County, Orange, California, USA, Galvis AE , Batoczki B ,   Department of Pediatrics, School of Medicine, University of Nevada Las Vegas, Las Vegas, Nevada, USA, Pecson IS ,   Children’s Lung Specialists, Las Vegas, Nevada, USA,   Department of Infectious Disease, Children’s Hospital of Orange County, Orange, California, USA, Sellers T ,   Summerlin Medical Center, Children’s Hospital, Las Vegas, Nevada, USA, Goroza E ,   4 Summerlin Medical Center, Children’s Hospital, Las Vegas, Nevada, USA 6 College of Osteopathic Medicine, Touro University, Henderson, Nevada, USA, Nakamura C ,   Children’s Lung Specialists, Las Vegas, Nevada, USA 2 Department of Pediatrics, School of Medicine, University of Nevada Las Vegas, Las Vegas, Nevada, USA
Published: November 2023

Tuberculosis (TB) remains the leading cause of death from a single infectious agent. Among children, TB can have a wide range of non-specific clinical and radiological manifestations becoming a challenging diagnosis, particularly in areas with a low prevalence. We present the case of a 14 month-old female with a history of fever of unknown origin (FUO) and later diagnosed with miliary tuberculosis.
Helicobacter pylori: A Belittled Cause of Immune Thrombocytopenic Purpura (ITP) and Role of Helicobacter pylori Eradication Therapy for Treating ITP
Authors:   Associate Professor, Medicine, Ad-din Women’s Medical College Hospital, Dhaka Bangladesh, Gomes Richmond R
Published: November 2023

Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterized by production of auto antibodies against platelet surface antigens. ITP affects women more often than men and is more common in children than adults. ITP is a diagnosis of exclusion after other identifiable etiologies have been ruled out. After the first report by Gasbarrini et al. (1998) showing rising platelet counts in ITP patients following Helicobacter pylori (HP) eradication therapy, there is growing evidence that highlights the role of HP in triggering ITP. The H-pylori infection induced ITP is validated by many proposed mechanisms such as molecular mimicry due to production of auto antibodies against H-pylori surface virulent factors (CagA) and cross reactivity of these antibodies with platelet surface antigens (GP IIb/IIIa, GP Ib/IX, and GP Ia/IIa), phagocytic perturbation due to enhanced phagocytic activity of monocytes, enhanced dendritic cell numbers and response, platelets aggregation due to presence of anti- H-pylori IgG and von Willebrand factor (vWf) and finally host immune response against H-pylori virulent factors CagA and VacA leading to ITP. Eradication of Helicobacter pylori infection has been variably associated with a platelet response in patients with immune thrombocytopenic purpura (ITP). Eradication therapy is simple and inexpensive, with limited toxicity and the advantage of avoiding long-term immunosuppressive treatment for those who respond. Although the evidence and follow-up are limited, it appears reasonable to routinely screen patients with ITP for H pylori, particularly in those populations with a high background prevalence of H pylori infection.
Prática pedagógica de professores do ensino fundamental no uso da internet como fonte de informação para pesquisa, na perspectiva da alfabetização científica
Authors: Conceição Simone da Silva , Lindner Edson Luiz
Published: November 2023

O objetivo da presente pesquisa é identificar a prática pedagógica de professores dos 4º e 5º anos do ensino fundamental, no uso da internet como fonte de informação para a pesquisa, na perspectiva da alfabetização científica. O trabalho se caracteriza como descritivo e qualitativo. O instrumento de coleta de dados utilizado é a entrevista semiestruturada. A análise dos dados foi realizada por meio da técnica de Análise Textual Discursiva (ATD) proposta por Moraes e Galiazzi. Após a aplicação da ATD, emergiram quatro categorias: Biblioteca; Fontes de Informação da Internet; Pesquisa Científica; e, Ensino e Aprendizagem. Os resultados demonstram as fontes de informação da internet que os professores utilizam são sites, blogs, vídeos do youtube, links, livros didáticos e jogos didáticos. Conclui-se que o estudo demonstra a fragilidades dos professores quanto à formação dos professores no que se refere à alfabetização científica, à pesquisa, uso das fontes e rigor científico.
Análise da rotulagem e teor de sódio de azeitonas em conservas comercializadas em supermercados de Teresina – PI
Authors: Silva Andreyssa Patrícia Alves da , Dias-Barbosa Cristina Zita de Morais Costa , Macedo Lívia de Sousa Oliveira , Silva Cynthia Siqueira , Carvalho Nayra Gabriele Fernandes de , Luz Rayssa Gabriela Lima Porto
Published: November 2023

A rotulagem de alimentos estabelece uma comunicação entre os produtores e os consumidores, auxiliando-os com informações sobre o produto. A comercialização de alimentos em conserva como as azeitonas vem crescendo a cada dia, e com isso aumenta também o consumo de sódio usados nos processos de conservação. Nessa perspectiva, a rotulagem tem um impacto bastante importante para os consumidores, quando apresentados de forma correta. Assim, a pesquisa teve como objetivo avaliar a conformidade da rotulagem geral, nutricional e o teor de sódio de azeitonas em conserva comercializadas em Teresina-PI. Para a verificação de conformidade e inconformidade foram elaborados checklist baseados nas legislações brasileiras, e a estatística dos dados consistiu em análise descritiva feitas no programa Microsoft Excel. Foram verificados 25 rótulos de 5 marcas diferentes, divididos em 6 categorias, sendo elas: azeitona verde com caroço (n=5), azeitona verde sem caroço (n=5), azeitona verde fatiada (n=5), azeitona preta com caroço (n=3), azeitona preta sem caroço (n=3), azeitona preta fatiada (n=4). Foi constatado uma média geral de 94% de conformidade para as legislações. Em relação ao teor de sódio, o maior índice foi 1.720mg e para o menor índice 1.085mg. Desse modo, faz-se necessário melhor fiscalização dos produtos pelos órgãos competentes e sugere-se que os consumidores consultem a rotulagem nutricional para adquirir produtos com menos taxas de sódio.
Alterações metabólicas associadas à COVID-19 em pacientes internados na unidade de terapia intensiva de um hospital universitário
Authors: Leite Erasmo Militão Nobre , Militão Andressa Rodrigues , Torres Eduardo Emanuel Alencar , Passos Cláudia Vanessa Borges da Silva , Santos Filho Efraim Ricardo Souza , Araújo Tiago Ferreira da Silva
Published: November 2023

Objetivo: Avaliar a relação de parâmetros laboratoriais com o desfecho clínico de pacientes com COVID-19 internados em uma unidade de terapia intensiva de um hospital universitário. Metodologia: Estudo longitudinal, observacional, retrospectivo, descritivo, comparativo e quantitativo, eticamente aprovado, executado na unidade de terapia intensiva de um hospital universitário que atuou prestando assistência à indivíduos com COVID-19, realizado através de uma análise dos parâmetros laboratoriais presentes nos prontuários eletrônicos dos pacientes infectados por coronavírus associando-os aos desfechos clínicos e empregando uma avaliação estatística por meio do teste T de Student não pareado para avaliação da média e erro padrão da média dos parâmetros e aplicação do teste Receiver Operating Characteristic Curve (ROC) para identificação dos pontos de corte mais sensíveis e específicos dos parâmetros que pudessem estar associados ao desfecho para óbito, considerando a significância p<0,05. Resultados e discussão: Dos 278 participantes, 63% eram homens; a partir da avaliação laboratorial dos parâmetros na admissão, a glicose e ureia obtiveram significância estatística; o tempo de internação médio foi maior entre indivíduos do sexo masculino (16 ± 0,9), além disso, para os parâmetros do desfecho clínico, observou-se que a glicose, hemoglobina, leucócitos, creatinina e ureia estavam significativamente superiores às referências, para a análise da curva ROC, os níveis de ureia associaram-se mais sensível e especificamente com o desfecho para óbito. Conclusão: Houve uma prevalência de homens na amostra; os parâmetros laboratoriais de glicose, hemoglobina, leucócitos, creatinina e ureia estiveram mais associados ao agravamento da COVID-19, possuindo uma relação direta com desfecho clínico para óbito.
Evidências científicas sobre métodos não farmacológicos para alívio da dor durante o parto normal
Authors: Ribeiro Maria Fernanda , Leal Yasmin Vieira , Oppenheimer Drauzio
Published: November 2023

Introdução: O parto normal é um processo de nascimento no qual possui diversas vantagens tanto para a mãe quanto para o bebê. Entretanto, a dor associada, frequentemente, desencoraja gestantes a optarem por essa via de parto. Ademais, o medo de complicações e as preferências individuais das mães contribuem para o aumento das taxas de cesárea eletiva. Mas, visando promover o parto natural, reduzir a ansiedade e, principalmente, a dor, as terapias não farmacológicas têm ganhado crescente aceitação, eles oferecem um atendimento abrangente, almejando humanizar o processo e permitindo um parto com o mínimo de intervenções possíveis. Objetivo: Analisar a eficácia de métodos não farmacológicos na redução da dor do parto normal. Métodos: Esta pesquisa é uma revisão bibliográfica integrativa que se concentra na avaliação de artigos, teses e estudos já publicados em revistas científicas dos últimos 10 anos, com o propósito de examinar a eficácia dos procedimentos não farmacológicos para alívio da dor durante o parto vaginal. Resultados: Foram selecionados 10 artigos na qual a maioria (70%) adotou o delineamento de ensaios clínicos randomizados e para medir a intensidade da dor, a Escala Visual Analógica foi amplamente empregada. Dentre os métodos não farmacológicos destacam-se, entre as mais frequentes, a acupuntura e suas variações. Conclusão: Conclui-se que todas as abordagens não farmacológicas analisadas, demonstraram importante eficácia no decréscimo da dor durante o trabalho do parto, entretanto, não se pode classificar qual o melhor, tendo em vista que não houve diferença significativa entre eles.
Doença periodontal relacionada a doenças respiratórias: Uma revisão integrativa da literatura
Authors: Palmeira Gabriela Ribeiro , Teixeira Isaiane Quadros , Melo Neto José Pereira de
Published: November 2023

Introdução: A periodontite é uma doença infecciosa que causa destruição dos ligamentos periodontais e ósseos, podendo ser um possível fator de risco para diversas doenças sistêmicas. Uma das principais causas de pneumonia em pacientes e pacientes imunocomprometidos é a aspiração orofaríngea, e a periodontite tem sido relatada epidemiologicamente como um possível fator de risco para pneumonia aspirativa. Objetivo: O objetivo do trabalho é identificar a literatura ou estado atual entre doenças periodontais e respiratórias. Metodologia: Foi realizado um levantamento por meio de busca sistemática nas bases de dados eletrônicas SCIELO; BVS; LILACS. Foram determinados como critérios a inclusão de artigos publicados que abordem a relação entre doença periodontal e doenças respiratórias nos últimos 10 anos. Os artigos são qualificados através da tabela CONSORT. Resultados: Resultados da busca em 99 artigos selecionados, observados critérios de inclusão e exclusão. Obtiveram-se assim 38 artigos, preenchidos na íntegra, passaram por diversos filtros e qualificados para segunda validação de qualidade metodológica. Dois itens selecionados, 1 com qualidade alta, 6 com qualidade moderada e 2 com qualidade baixa, foram selecionados entre 9 itens potencialmente úteis. Conclusão: Concluo que existe relação entre doença periodontal e doenças respiratórias, porém, recomendamos a realização de estudos adicionais utilizando metodologias alternativas para obter maior clareza sobre esta relação causal.
Perda de células do endotélio corneano e alteração da espessura da córnea após cirurgia de catarata: Uma revisão narrativa da literatura
Authors: Oliveira Paulo Franco de , Santos Maria Fernanda Franco , Mendonça Ana Carolina Matiotti , Porto Carla Pereira Santos
Published: November 2023

A catarata é uma doença ocular comum e, continua sendo a principal causa de cegueira reversível em todo o mundo. Até alguns anos atrás, a indicação de uma cirurgia de catarata era realizada somente após uma baixa visual bastante pronunciada. Com a evolução da tecnologia e com o advento da facoemulsificação, a indicação desta cirurgia é cada vez mais precoce. Contudo, ela continua apresentando desafios e riscos. A manipulação intra-ocular, como a que ocorre durante a cirurgia de catarata por facoemulsificação, causa turbulência de fluidos e fragmentos do cristalino, que podem levar ao dano endotelial, resultando no comprometimento transitório da função ou perda celular permanente. O presente estudo tem como objetivo avaliar a perda de células endoteliais, e suas impactações, em pacientes submetidos à cirurgia de catarata. Trata-se de uma revisão narrativa, onde serão comparadas a quantidade de células endoteliais e a espessura corneana, antes e após a cirurgia de catarata por facoemulsificação. Serão utilizados mais de 20 artigos, que terão seus dados analisados e comparados sistematicamente. Espera-se uma elucidação dos fatores mais comumente associados a maiores perdas endoteliais, e possíveis afecções visuais, bem como a avaliação da segurança da cirurgia de catarata nos dias atuais.
Validação de tecnologia educativa para comunicação do diagnóstico entre profissionais da saúde e a criança com câncer
Authors: Lima Tatiany Lisiére Brandão Künzler , Gontijo Daniela Tavares , Coriolano-Marinus Maria Wanderleya de Lavor , Falcão Ilka Veras
Published: November 2023

Objetivo: Validar, com especialistas, uma teconologia educativa direcionada para a comunicação entre profissionais da saúde e a criança com câncer sobre seu diagnóstico e processo de tratamento. Metodologia: estudo metodológico do tipo estudo de validação de tecnologia educativa quanto ao seu conteúdo e aparência, com análise quantitativa e qualitativa dos dados. Participaram 27 juízes especialistas em oncologia pediátrica e/ou comunicação de más-notícias, profissionais da saúde. Foram considerados os domínios: Objetivos, Relevância, Conteúdo, Linguagem, Ilustrações, Layout, Motivação e Material de apoio. Resultados: Os dados quantitativos foram analisados através do Índice de Validação de Conteúdo (IVC) com ponto de corte 80% e os dados qualitativos foram submetidos a analise de conteúdo temática e discutidos de forma articulada com a literatura pertinente na área, visando o aperfeiçoamento e adequação do material. A tecnologia Flor da Raiz Vermelha foi validada com IVC total de 94%. Conclusão: O alto índice de validade obtido aponta a tecnologia Flor da Raiz Vermelha, como estratégia mediadora para que o profissional da saúde possa comunicar-se com a criança com câncer sobre seu diagnóstico e processo de tratamento, através de uma abordagem lúdica e sensível às necessidades de cada criança.
Keputusan investasi dalam menghadapi isu resesi 2023
Authors: Mau Ignatia Thomasita Bau , Wutun Maria B.M.G. , Burin Stefanie N.B. , Man Stanis , Fallo Apryanus , Goetha Selfiana , Niha Simon Sia , Manafe Henny , Djuang Gaudensius
Published: November 2023

Menanggapi isu-isu ekonomi global seperti resesi ekonomi 2023, Tim Dosen Manajemen Universitas Katolik Widya Mandira Kupang melakukan kegiatan pengabdian kepada masyarakat guna memberikan sosialisasi terkait dengan investasi yang dapat menjadi solusi untuk meminimalkan diri, dari segala kondisi ekonomi global yang tidak menentu seperti resesi ekonomi tersebut. Masyarakat di Kecamatan Kupang Barat dipilih sebagai peserta dalam kegiatan sosialisasi ini karena masyarakat disana mempunyai potensi penghasilan yang baik, dari segi pertanian, perkebunan, peternakan maupun saranadan lembaga keuangan yang dapat menjadi penunjang untuk melakukan investasi. Menyukseskan kegiatan pengabdian kepada masyarakat ini, dan agar informasi dalam sosialisasi ini menjadi tersampaikan dengan tepat, sosialisasi ini dilakukan pada siswa dan siswi di SMA Negeri I Kupang Barat. Tujuannya karena siswa dan siswi sekolah lebih mengerti tentang materi investasi dan dapat menjadi sumber informasi untuk keluarga dirumah, yang adalah masyarakat di Kupang Barat sendiri. Kegiatan pengabdian kepada masyarakat ini berhasil dilakukan dan peserta dapat mengikuti semua tahapan sosialisasi dengan baik sampai pada melakukan simulasi awal penggunaan aplikasi yang dapat dijadikan platform untuk melakukan investasi saham atau produk investasi lainnya.