bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring Strategy of Geological Hazards Using Integrated Three-dimensional InSAR and GNSS Technologies with Case Study
Authors: Bányai László , Bozsó István , Szűcs Eszter , Gribovszki Katalin , Wesztergom Viktor
Published: June 2023

Geodetic/geodynamic benchmarks, equipped with both ascending and descending radar corner reflectors, and a method for integrated InSAR and GNSS/GPS network observation were developed and applied as the continuation of the former geodetic monitoring at the Dunaszekcső landslide, Hungary. The attempts to apply InSAR technologies using archive and Sentinel-1 data practically failed on the most intensive landside areas (“Vár” and “Szent János” hills), where proper persistent or distributed scatterers were not found. Our concept solved this problem, where the Simple Look Complex (SLC) images are used to interpolate the movements between two GNSS network observations using the integrated benchmarks and the method of Kalman-filtering. Since the InSAR line-of-sight (LOS) changes are barely sensitive to the north movements, this information is essentially provided by GNSS measurement alone, moreover, the GNSS measurements are used to: a) identify the benchmarks, b) detect the unwrapping errors and missing cycles and c) provide the boundary values of Kalman-filtering.After the installation of benchmarks three GPS observations were carried out and 69 ascending and 61 descending Sentinel-1 A and B images were processed. The data processing properly indicated the general movement history, which fit the curves of former geodetic observations, as well. The dense data points of the East and Up (vertical) components made possible more detailed geomorphologic interpretations of the ongoing process between two GPS observations. During the investigated periods the deceleration of movements was experienced, however, the deceleration of the dormant state needs the continuation of the monitoring.
Impacts Of Ethno-Religious Crisis On Settlement Patterns, Socialization And Social Studies Students’ Achievement At The University Of Jos, Nigeria
Authors: Shitu Lukman Olayinka
Published: June 2023

This study investigated the impact of ethno-religious crisis on settlement patterns and social studies students’ socialization at the University of Jos. With the volatility of Jos the capital of Plateau state to ethno-religious crisis it becomes pertinent to investigate issues of ethno-religious crisis and how it impacted on student’s settlement patterns and social life within Jos metropolis. The study employed a cross sectional survey research design. The study made use of undergraduate social studies students for the academic session 2020/2021. A sample of 200 students were selected using proportional random sampling technique and the sample was cut across 100 level to 400level with both gender given equal consideration. The data used for the study were collected using a structured questionnaire which was subjected to face and content validity of experts. The data collected were analysed through using both descriptive and inferential statistic. The study findings revealed that, ethno-religious crisis affects settlement patterns of students in Jos North and has caused the redrawing of Jos map. This also affects freedom of socialization as students are restricted from moving through some environments that is perceived as dangerous, this erroneous belief could affect students achievement adversely. The study recommended that, there should be adequate hostels to accommodate students within the campuses so that students will not be exposed to the risk of ethno-religious crises outside the campus. Also, government should provide needed atmosphere in terms of policy and flexible framework that will ensure peaceful co-existence among others.
Analysis of the operation of the electrical current supply scheme to two cables of a multilayer wire rope
Authors: Belmas I , Bilous O , Tancura G , Shvachka A
Published: June 2023

Purpose. Regular inspection of cables on cable-stayed bridges is key to ensuring the safety of people's lives. However, the detection signals are usually complicated by the interwoven structures of the ropes, which cause the rope defect signal and the strand signal to be mixed. To ensure the working capacity of the wire rope, it is necessary to regularly check the integrity of the cables. Research methodology. Analytical methods of observations and mathematical and statistical data processing are used in the work; system analysis when developing criteria for assessing the actual technical condition of wire ropes; the method of mathematical modeling in the development of prognostic models of cable breaks. Research results. The paper analyzes the cable rope control system when changing the parameters of the lengths of the electric current applied to two cables, and shows the nature of the distribution when the number of the damaged cable is changed to another. The obtained results demonstrate the necessity of using this method of input, because the system clearly works in different cases. Scientific novelty. The automatic cable break detection system with the function of determining the place of damage allows in automatic mode during the operation of a lifting machine equipped with a flat rubber rope to monitor the technical condition of the cables vulcanized in a rubber shell and to stop the machine in the event of a break of any cable. The change in the electric voltage between the ends of the twisted cable depends on the length of the rope as follows: with a rope length of 10 m - the potential difference does not exceed 7V, and at 100 m - 106, at 300 m - 1015 proportionally depends on the square root and the product of the electrical resistance of the cable and the specific conductivity of rubber layers of rope. Practical value. The introduction of an automatic control system will make it possible to quickly make decisions aimed at eliminating damage to flat single-layer and cable-stayed multi-layer ropes, stop the "development" of damage, reduce time spent on restoring the working condition of the lifting machine, and most importantly - increase its reliability and safety of operation.
Dominance of human Influenza H1N1pdm09 in flu like patients during early two months of 2020
Authors: Rahim Rummana , Hasan Abu , Hasan Nazmul , Ara Nikhat , Biswas Suma Mita , Rahman Mizanur
Published: June 2023

Introduction:Influenza is a worldwide respiratory infectious disease which affect all age groups and associated with significant number of morbidity and mortality each year. The circulating subtypes varies countrywide yearly, and it helps policy maker to get preparedness for early effective management of influenza epidemics.

Materials and methods Nasal swabs were collected from 463 patients in January and February 2020 presenting flu-like symptoms and Rapid Influenza Diagnostics Tests (RIDTs) were performed for influenza A & B screening as a routine test. Then influenza A subtyping was done by RT-PCR followed by gel electrophoresis of 27 influenza positive samples.

Result Among 463 cases, 106 (22.9%) were Influenza positive with huge (99.06%) dominance of Influenza A. Subtyping of randomly selected outpatient derived 27 Influenza A positive cases showed flourishing presence of seasonal Influenza A/H1N1pdm09 (21; 77.8%).

Conclusion This small study warrants further elaborate investigation to know circulating influenza A subtyping in the country which may assist health care providers in making treatment decisions and hence, appropriate patient management.

Pulse Volume 12-14 2020-2022 p.4-9
Is Helminthiasis a Precipitating Factor for Frequently Relapsing Nephrotic Syndrome?
Authors: Sultana Sabina , Hanif Mohammed , Luna Sharmin Akter
Published: June 2023

Nephrotic Syndrome (NS) is a common childhood illness. It is a disease of relapse and remission with major concern to manage the cases with relapse. Helminthiasis also a common problem in our subcontinent. So, it is very important to find out any relation with helminthiasis and relapse in children. In our study, 88 patients, clinically diagnosed as minimal change nephrotic syndrome, were studied to find out any relationship with helminthiasis and frequent relapse. 36 patients (40.9%) had no helminthic infection, 34 patients (38.6%) had helminthiasis and 18 patients (20.5%) had atopic disorders. 62 patients were successfully followed up for 6 months. Relapses occurred 47.8% (11/23) patients in non-helminthiasis group. 88.5% (23/26) in helminthiasis group and 84.6% (11/13) in atopic group, patients who completed follow up. Thirteen percent (3) patients in non-helminthiasis group, 50% (13) in helminthiasis group and 38.5% (5) in atopic group were found to be frequent relapser. The differences were statistically significant.

Pulse Volume 12-14 2020-2022 p.10-12
Patient safety culture plays an essential role to ensure safe patient care and quality in healthcare services
Authors: Rahman Tahmina , Ahmed Rezina , Mahmud Arif
Published: June 2023

Patient Safety is a global health priority. Every year, millions of patients suffer or die because of unsafe and poor- health care service. There are several factors which compromise patient safety and cause potential harm in health care settings. In developed countries, it is estimated that one in every 10 patients is harmed while receiving care in hospital. In developing countries, there is inadequate information on adverse event due to poor quality of health care service. Despite recent developments in Bangladesh, there is still great concern about the quality of care in healthcare sector. Evercare Hospital Dhaka is one of the leading private health care organizations in the country and committed towards patient safety from the very beginning. The purpose of this article is to discuss the importance of patient safety culture at healthcare service and how it is nurtured at Evercare hospital Dhaka by following the joint commission international standards.

Pulse Volume 12-14 2020-2022 p.53-61
SUBSTANTIATION OF THE METHODOLOGY FOR CALCULATING THE FUEL CONSUMPTION AND FUEL STATUS UNITS FOR PUBLIC UTILITY NEEDS DURING THE PREPARATION FOR COMBAT ACTIONS
Authors:   The National academy of hte National Guard of Ukraine, Derevianko M. , Hetman P. ,   National Guard of Ukraine, Mudryk V. ,   The National academy of hte National Guard of Ukraine
Published: June 2023

The paper substantiates the urgency of using methodological recommendations for calculating the fuel consumption to find the public utility needs solutions in the field conditions, which is an integral component of housing maintenance in the general system of logistics support of troops. In order to create normal living conditions, to cook hot food, to maintain a favourable temperature regime inside the buildings and warming posts for personnel, at duty stations, it is necessary to have a scientific and methodological apparatus that will allow to make the correct and well grounded decision on units’ fuelling to find the public utility needs solutions in the field conditions. Especially when performing combat missions, the timely and uninterrupted solution of public utility issues plays a significant role in increasing combat readiness and maintaining a high morale and psychological condition of servicemen. The final result of calculating the fuel requirement to find the public utility needs solutions is influenced by a large number of various factors that must be taken into account when conducting appropriate calculations and planning and organizational measures. With the help of the proposed expressions, it is possible to determine the fuel consumption for public utility needs, for hot food cooking both for a separate duty station (subunit) and for a military unit (grouping) as a whole.
LEGAL REGULATION OF FUEL AND LUBRICANT SUPPLY SERVICES: ANALYSIS OF PROBLEMS AND PROPOSALS FOR THEIR SOLUTION
Authors:   National Academy of the State Border Guard Service of Ukraine named after Bogdan Khmelnytsky, Kupriyenko D. , Sahan V. ,   National Academy of the State Border Guard Service of Ukraine named after Bogdan Khmelnytsky, Levchuk N. ,   National Academy of the State Border Guard Service of Ukraine named after Bogdan Khmelnytsky
Published: June 2023

The article is devoted to the analysis of the state of regulatory and legal regulation of the activity of the fuel and lubricant supply service of the State Border Guard Service of Ukraine. The official duties of the officials of the fuel and lubricant supply service are determined by the Statutes of the Armed Forces of Ukraine, the order of the Administration of the State Border Guard Service of Ukraine dated June 24, 2008 No. 544 "On the approval of the Guidelines on the provision of fuel to the bodies of the State Border Guard Service of Ukraine", as well as the order of the Administration of the State Border Guard Service of Ukraine of the Border Service of Ukraine dated December 21, 2020 No. 134 "On the approval of the Advisor on military (ship) management of the State Border Service of Ukraine." The review of the regulatory legal support of the fuel and lubricant supply service of the State Border Guard Service of Ukraine made it possible to establish that the duties of the officials of the fuel and lubricant supply service include tasks related to: monitoring the quality and proper use of fuel, planning the necessary efficiency measures and feasibility of using and saving fuel; organization of maintenance, improvement and operation of fuel warehouses, filling stations and other subordinate fuel service facilities in accordance with current regulatory documents; ensuring proper use, maintenance and storage of technical means; organization and maintenance of accounting and reporting on fuel service; collection, delivery and proper use of spent oil products, etc. The procedure for performing these tasks must be regulated by relevant departmental acts. At the same time, the governing documents of the State Border Service of Ukraine and the Ministry of Internal Affairs of Ukraine do not define the procedure for performing the specified tasks. According to the authors, it is the task that regulates the order and conditions of storage of fuel and lubricant materials, special liquids at fuel warehouses and filling stations; tasks of fuel quality control; maintenance of technical means of the fuel and lubricant supply service are fundamentally important for the high-quality organization of the activities of state border protection units and must be regulated for the high-quality performance of official duties by officials of the State Border Service of Ukraine, who are assigned the tasks of organizing and managing the military (ship) economy.
COMPUTER MODELLING OF SCATTERING OF E-POLARISED WAVES ON A SHIELDED GC-LIKED REFLECTOR SYSTEM
Authors:   The National academy of hte National Guard of Ukraine, Dushkin V.
Published: June 2023

Computer simulation of electromagnetic wave scattering on a shielded periodic reflector system, with a special period structure is considered. The electrodynamic reflective structure consists of a screen and a periodic system of strips. The cross-section of the strips is a system of segments formed by the principle of constructing a generalized Cantor set at each of the periods. Іt was used a mathematical model based on the reduction of the initial boundary value problems for the Helmholtz equation to systems of singular integral equations. The choice of this approach did not require analytical calculations when changing the number of lattice elements. Using this approach, it was not necessary to make changes to the computer implementation of the algorithm. The computer experiment has proved the possibility of applying the discrete singularities method computational scheme for the considered structure. It is proved that the structure constructed according to the proposed principle has the properties of broadband and multimode for the studied values of the structure parameters. In particular, for the studied structures, the resonance occurred when the wavenumber was changed from 0 to 50, with a significant increase in amplitude occurring at harmonics with numbers up to 40. This phenomenon led to a complex structure of the lines of the absolute values of the amplitude of the scattered electric field above the grating. The presence of small areas with an increase in the amplitude of the scattered field by a factor of 5-6 compared to the amplitude the incident electromagnetic wave was observed. These properties show practical interest in the use of this type of antennas to improve electronic camouflage and tactical radio communications. In the future, it is planned to conduct computer simulations for imperfectly conducting structures and compare the results with the numerical results for the ideal case discussed in this paper.
ESTIMATION OF THE INFLUENCE OF «CONSTRUCTIONAL» FRICTION IN SUSPENSION ON SPATIAL VIBRATIONS OF A VEHICLE
Authors:   The National academy of hte National Guard of Ukraine, Pisarev V. , Kornev O. ,   The National academy of hte National Guard of Ukraine
Published: June 2023

In the process of creating and modernizing ground vehicles for various purposes, in particular armored vehicles, there is a problem of assessing the influence of design features on working processes in operating conditions. These features include the presence of "structural" friction, in its manifestations and the effect similar to "dry" friction. In some cases, this leads to the appearance of self-oscillations, which is undesirable. Therefore, the development of the theory and practice of numerical assessment of vehicle performance with the possibility of manifestation of self-oscillating properties is an urgent task. Obviously, in the framework of the methodology of applied optimal design of complex technical systems, it is necessary to have an adequate mathematical model of the object of study. An original mathematical model of free spatial vibrations of the sprung part of the transport machine (body) is proposed, which allows one to evaluate the influence of the features of the new vehicle suspension design. The new suspension is hydropneumatic, with a helical gear, with the presence of "structural" friction. Calculations carried out numerically using the original program confirmed the correspondence of the mathematical model to modern ideas about the theory and practice of work processes with free vibrations of complex technical systems. The motion parameters during the manifestation of self-oscillating properties and parametric vibrations of an object close in weight and size to the BTR70 and BTR80 are numerically estimated.
3 D MODELING OF FOUR-AXLE MACHINE MANEUVERING
Authors:   Kharkiv National Automobile and Highway University, Chernikov O. , Garmash V. ,   The National academy of hte National Guard of Ukraine
Published: June 2023

One of the ways to increase the maneuverability of the wheeled vehicles of the National Guard of Ukraine is to use a four-axle wheeled chassis with two turntables, which will allow the machine to turn with the smallest radius, move crab, sideways and turn around its own vertical axis. The creation of such a chassis is associated with a large amount of various experiments and tests of the finished sample. The development of computer technology and technologies has led to the creation of software applications for computer (simulation) modeling, which allow research and study of the properties of technical objects and systems under different conditions. The article developed a digital model of the chassis of a four-axle machine with two turntables and identified its features. For modeling, a powerful package of solid modeling Autodesk Inventor was chosen, which provides a comprehensive flexible set of tools for 3D design, visualization, instrumentation, analysis and calculations. When building a general 3D model of the chassis, the main features of the layout of parts and assemblies of this wheeled vehicle were taken into account. The forced rotation of the wheels and the rotation of the platforms were modeled by entering the value of a single parameter or setting using a graph. Depending on the needs of the experiment, graphs were set for displacements, speed or acceleration. In the course of a visual experiment, a simulation of the maneuvering of a four-axle vehicle was carried out for three options: turning the chassis to move in the opposite direction; changing the direction of movement through the turn of the chassis is a difficult maneuver; turning the chassis for sideways movement. The analysis of virtual studies showed that the control of the front, rear or both turntables is a promising way to increase the maneuverability of wheeled vehicles. In addition, the created computer prototype allows you to determine the main characteristics of the future product, carry out analysis, upgrade and necessary modification, set the desired trajectory of movement, including when passing through obstacles.
Clinical Features and Visual Prognosis of Retinal Vein Occlusion in Those under 50 Years Old
Authors: Jung Soyeon , Shin Haeeun , Chin Hee Seung
Published: June 2023

Purpose: To analyze the clinical features and visual prognosis of retinal vein occlusion (RVO) in patients under 50 years of age.Methods: A retrospective analysis of medical records of 36 patients under 50 years of age diagnosed with RVO from January 2016 to October 2021.Results: The mean age was 39.53 ± 9.98 years and 50%, 44.4%, and 5.6% had branch, central, and hemi-central RVO, respectively. Before the RVO diagnosis, systemic disease had been diagnosed in 38.9%. Further, 13.89% of the cases had a new systemic disease diagnosed after the diagnosis of RVO. Hypercholesterolemia was observed in 47.6%. The initial visual acuity (VA), best corrected visual acuity (BCVA), and central subfield thickness (CST) showed significant correlations with the final VA, BCVA, and CST.Conclusions: In patients with RVO under the age of 50 years, the initial VA and CST can be used as indicators to determine whether treatment is necessary by reflecting the final VA and CST. The initial VA and CST can also be used to predict the visual prognosis. Even at a young age, if complications occur, the visual prognosis of RVO may be poor, so an evaluation of the patient’s general condition is essential, especially the blood cholesterol level.
A Case of Full-thickness Macular Hole Formation Secondary to Laser Retinopexy
Authors: Lee Gahye , Bae Kunho
Published: June 2023

Purpose: To report a case of full-thickness macular hole (FTMH) formation secondary to demarcation laser retinopexy in a retinal break with localized retinal detachment patient.Case summary: A 59-year-old male visited our clinic with ocular discomfort in both eyes. Uncorrected visual acuity (UCVA) was 0.63 in right eye. Large retinal break in 1:30 o/c, localized retinal detachment and laser marking scars all around the right eye were found in fundoscopic exam. Posterior-vitreous detachment or vitreomacular traction was not observed in optical coherence tomography (OCT). Demarcation laser retinopexy was performed around the margin of retinal detachment and peripheral degenerative lesions. Three months after demarcation laser retinopexy, UCVA in right eye of the patient was decreased to 0.16 and full thickness macular hole was observed on OCT examination. Pars planar vitrectomy, internal limiting membrane peeling, and SF6 gas tamponade were performed in the right eye. One month after the surgery, closure of FTMH was observed. Three months after surgery, there were no recurrence of FTMH in the right eye.Conclusions: Demarcation laser photocoagulation of localized retinal detachments may predispose to FTMH formation. Even though it can be occurred rarely, follow-up check-up is necessary in consideration of the possibility of FTMH, which can cause serious visual loss.
The Effectiveness of a Counseling Program Based on the Cognitive Load Theory in Developing Logical Thinking for Kindergarten Children
Authors: Hosny Doa'a
Published: June 2023

The current research aimed at developing logical thinking for kindergarten children, through the use of a counseling program based on the cognitive load theory, and to identify the continuity of the effectiveness of the program after the end of the application and during the follow-up evaluation. To achieve this goal, the research sample consisted of (60) children at early childhood stage, and they were divided into two groups (i.e. experimental – control group), with equivalence in the experimental group in variables of age, intelligence and logical thinking. The following tools were used: Raven's Colored progressive matrices test of intelligence (prepared, modified and rationed by Ali, 2016), Logical Thinking Scale for Kindergarten Children (Prepared by the author), and a Counseling Program Based on the Cognitive Load Theory to Develop Logical Thinking for Kindergarten Children (Prepared by the author). It were found statistically significant differences between the mean scores of the experimental group members in the pre- and post-measurements on the logical thinking scale for children in favor of the post-measurement after the application of the program, and there were also statistically significant differences between the mean scores of the experimental and control group in the logical thinking scale for children in favor of the experimental group, while no statistically significant differences were found between the mean scores of the experimental group members in the post and follow-up measurements on the logical thinking scale.
III. Amenhotep İle Amon Rahipleri Arasındaki Mücadele
Authors: MUHSİN HAJİ AZEEZ BABİLA Muhsin
Published: June 2023

Tanrı Aton’u merkeze alan yeni bir inanç sistemi ortaya koymuş olan Akhenaton’un hayatı Tanrı Amon rahipleri ile mücadele ile geçmiştir. Bu mücadele Eski Mısır tarihinin belki de en meşhur olayı olarak insanlara yansıtılmıştır. Fakat Eski Mısır’da sosyal hayatın büyük kısmını yöneten ve sahip oldukları güç ile siyasi konum kazanmaya çalışan Amon rahipleri ile diğer Mısır kralları arasındaki mücadele gölgede kalmıştır. Akhenaton’un babası olan III. Amenhotep’de hem saraydaki Amon rahiplerinin taraftarları hem de krallığın dört köşesine yayılmış olan tapınaklardaki Amon rahipleri ile mücadele etmiştir. III. Amenhotep geleneğin aksine kardeşleri veya saray ahalisinden biri ile evlenmemiş ve Tanrı Amon’un emirlerine karşı gelmiştir. Ayrıca kraliyetin önemli makamlarına yerleşmiş olan Amon rahiplerinin yerine askeri ve sivil kökenli kişiler atamış bu durum sorunlar ortaya çıkarmıştır. Bu çalışma III. Amenhotep döneminde, siyasi hayatı yönlendirmeye çalışan Amon Rahipleri ile Mısır kralı arasındaki mücadeleyi, dönemin kaynakları üzerinden açıklamayı amaçlamaktadır.
Análise da saúde mental de profissionais da atenção primária no município de Lagarto-SE na pandemia do COVID-19
Authors: Souza Caio Robert Rodrigues Martins de , Santos Sanja Nayane Oliveira , Fróes João Pedro Oliveira , Santana Emilly Layane Santos , Santana Gabriela da Silva , Carvalho Kervem Viana , Geraldini Janaína Rodrigues
Published: June 2023

A pandemia causada pelo COVID-19 acarretou diversos danos individuais e sociais por tratar-se de uma doença atípica e desconhecida. Nos sistemas de saúde, desencadeia efeitos cumulativos para os próprios profissionais da área e usuários dos serviços. O presente estudo compartilha os dados encontrados e analisa a saúde mental dos profissionais da Unidade Básica de Saúde do município de Lagarto-SE quanto ao estilo de vida, emocional, estresse e humor. A coleta de dados e os seus respectivos gráficos foram retirados dos questionários, adaptados de instrumentos, formulados na plataforma Google Forms. Resultados demonstram dano ao  bem estar psicológico dos profissionais durante a pandemia, tanto na autopercepção (76,9%) como no diagnóstico (46,2%). Conclui-se que apesar do artigo não possuir percentual elevado quanto ao sobrecarregamento mental dos profissionais da saúde, contrapondo outras pesquisas, faz-se necessário novas pesquisas científicas e programas destinados à saúde mental dos profissionais.
Aplicação da ferramenta FMEA para análise de notificações de queixas técnicas de medicamentos líquidos no contexto de Quality by Design
Authors: Silva Gabriela Vieira da , Giorgetti Leandro , Pereira Luiza Novaes Alves , Neves Luiza Saraiva
Published: June 2023

Diante o crescimento da indústria farmacêutica nos últimos anos, diferentes abordagens podem ser adotadas no delineamento de processos de fabricação de medicamentos, visando a obtenção de produtos cada vez mais seguros e eficazes. A utilização de diferentes estratégias e tecnologias são necessárias para assegurar a identificação de todos os potenciais pontos de falhas e a otimização dos controles implementados nas etapas de manufatura. Neste contexto, o conceito de Quality by Design (QbD), amplamente promovido pela agência Food and Drug Administration (FDA) e pela Conferência Internacional de Harmonização (ICH) vem se destacando no Brasil, por consistir em uma abordagem fundamentada no desenvolvimento sistemático de produtos por meio da utilização de diversas ferramentas, com base no gerenciamento de riscos de qualidade aliado à redução de custos, a fim de promover a melhoria contínua da cadeia de produção de medicamentos. O estudo apresentou uma análise quantitativa das causas de falhas potenciais notificadas pelo site oficial da ANVISA durante o período de 2020 a 2022, através da avaliação do RPN elaborada pela ferramenta FMEA dentro do contexto de QbD. Foram analisadas 453 queixas técnicas, sendo 71 queixas (15,7%) sobre medicamentos líquidos, sendo aproximadamente 77,5% referentes a problemas farmacotécnicos como embalagem, aspecto e formulação. O conceito QbD para gestão de riscos e princípios de fabricação, visa a redução de custos e implementação de estratégias de controle no desenvolvimento do processo e da formulação, que possibilitem a diminuição gradativa do número de queixas técnicas destes produtos, assim como a redução de falhas e erros humanos.
Diagnostic assessment of the comfort of palliative patients: scoping review protocol
Authors: Pereira Jorge Miguel , Castro Maria Luísa , Duarte Ivone , Lourenço Marisa
Published: June 2023

Introduction: The competence to evaluate is essential in any profession in the health area. The concept of comfort is intrinsically linked to palliative care, being a concern shared by any health professional. These, when analyzing, must know what they are looking for and what they should expect to find. Objectives: To map how health professionals assess people's comfort in palliative and end-of-life situations. Methods: will follow the methodology proposed by the Johanna Briggs Institute (JBI) for scoping reviews. Considered studies in Spanish, English and Portuguese, without temporal definition. Databases to search: MEDLINE Complete, Academic Search Complete, CINAHL Complete and Mediclatina (EBSCOhost), Scopus and Web of Science Core Collection. For unpublished studies, the RCAAP (open access repository in Portugal) will be used. Two independent reviewers will evaluate the articles and extract the data using a specific tool created. In case of discrepancies, a third reviewer will be requested. Results: It is expected to map the data used by health professionals in assessing the comfort of people in palliative care. Conclusions: This review will make it possible to identify instruments used to collect data and what is the professional competence of the group that has in its practice the assessment of comfort. This can form the basis for a systematic review and/or help identify gaps where it may be important to invest in the future. This protocol was registered on the OSF platform with the DOI: 10.17605/OSF.IO/UF52X.
A fisiopatologia da obesidade e sua abordagem terapêutica nutricional com uso de nutracêuticos
Authors: Machado Natália Guerra , Almeida Nathalia Cristhina Melo Campos , Maynard Dayanne da Costa
Published: June 2023

A obesidade acende um alerta na atualidade, que pode ser um problema de saúde pública de caráter epidêmico, sobrecarregando o Sistema Único de Saúde (SUS).  É uma doença multifatorial de risco para diversas patologias, como diabetes, hipertensão, síndrome metabólica, problemas cardiovasculares, ortopédicos e pulmonares. Suas causas estão relacionadas a um estilo de vida sedentário, alimentação desajustada ao estado nutricional, genética, problemas comportamentais e ambiente obesogênico. Esse trabalho teve como objetivo trazer a terapêutica nutricional no tratamento da obesidade, como uso de nutracêuticos associados. Foi realizada uma revisão da literatura com artigos publicados nos últimos 8 anos. Como resultado, foi verificado que o uso de alguns nutracêuticos apresentou resultados positivos, como a melhora do perfil lipídico, de marcadores inflamatórios e redução do IMC. Porém, se faz necessária a realização de mais pesquisas, mais longas e com público mais abrangente, já que as pesquisas realizadas foram feitas em pequenas amostras e estudos em um pequeno espaço de tempo, apresentando resultados inconsistentes na perda de peso e perda de massa gorda em si, o que impede uma melhor e mais precisa análise sobre o assunto abordado, entre diversas variáveis relevantes.
Os profissionais de saúde e cuidados paliativos em pediatria: revisão bibliográfica
Authors: Teixeira Deuselina Gabriela Soares , Sales Helder Júnior Gualter , Neves Ana Lia Silva , Marques Gabrielle Agostinho Rolim
Published: June 2023

Introdução: Um dos princípios básicos para o cuidado paliativo infantil é o cuidado focado na criança, orientado a toda família, construído com uma boa relação equipe-família. Para tanto, a equipe multiprofissional deve estar apta a atender as necessidades da criança de forma integral, viabilizando ações que garantam uma sobrevida digna e controle adequado dos sintomas compreendendo o paciente e sua família na sua subjetividade e complexidade. Objetivo: Analisar os profissionais de saúde e os cuidados paliativos em pediatria por meio de uma revisão bibliográfica. Método: Tratou-se de uma revisão bibliográfica exploratória com abordagem qualitativa. Resultados: A partir da combinação dos descritores foram obtidos 117 estudos. Numa avaliação inicial por meio dos resumos, verificou-se que 83 estavam fora do recorte temporal, 21 não respondiam a questão norteadora, portanto, 104 artigos foram excluídos. Sendo possível selecionar 13 artigos para compor a amostra final desta revisão bibliográfica. Conclusão: Constatou-se a significativa contribuição dos profissionais de saúde em cuidados paliativos na pediatria, nos estudos analisados. Entretanto, notou-se ainda que há necessidade de mais atenção para a área nos centros de saúde e instituições de ensino, formando assim, profissionais mais capacitados para lidar com o contexto. Os cuidados paliativos são de suma importância na pediatria, tendo em vista que lidar com a terminalidade infantil representa, grande maioria das vezes, um impasse para a equipe de saúde e aos familiares, sendo cada vez mais necessários  estudos com intuito de aprofundar conhecimentos na área.
CURCUMIN, THE BIOACTIVE COMPOUND OF TURMERIC, MAY IMPROVE THE ANTI-MALIGNANT PROPERTY OF GEMCITABINE IN PROSTATE CANCER CELLS
Authors: ERZURUMLU Yalçın , DOĞAN Hatice Kübra , ÇATAKLI Deniz
Published: June 2023

Objective: The aim of this study was to investigate the possible synergistic effect of curcumin on the anticancer features of gemcitabine on prostate cancer cells.
Material and Method: The human prostate adenocarcinoma cell line LNCaP was used in the studies. The effect of the co-administration of gemcitabine and curcumin on the viability of LNCaP cells was investigated by the WST-1 assay. Autophagy, ubiquitin-proteasome system (UPS), unfolded protein response (UPR) and cell death-associated proteins, androgenic signaling, proto-oncogenic, angiogenic and epithelial-mesenchymal transition (EMT) associated protein levels were investigated by immunoblotting studies.
Result and Discussion: Our results showed that curcumin potentiated the anticancer effects of gemcitabine on LNCaP cells. Co-administration of curcumin and gemcitabine strengthened the suppressive effect of gemcitabine on cell viability. Moreover, co-administration modulated the autophagy, more strongly stimulated UPS and UPR, suppressed androgenic signaling, led to the activation of cell death-related poly [ADP-ribose] polymerase 1 (PARP-1) and caspase-3 and strongly suppressed the expression levels of proto-oncogenic c-Myc and angiogenic vascular endothelial growth factor-A (VEGF-A). In addition, it was determined that co-administration negatively regulated EMT by stimulating E-cadherin expression and suppressing N-cadherin level. These results suggest that the combined usage of gemcitabine and curcumin may offer a potent therapeutic approach to prostate cancer by enhancing the anticancer effects of gemcitabine.
Engaging first-year engineering students in hybrid/blended teaching and learning activities
Authors:   Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China., Dutta Shanta , He Mingjing ,   Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China., Leung Andy ,   Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China., Chan Tak-Ming ,   Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China., C. W. Tsang Daniel ,   Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Published: June 2023

Prompted by social distancing regulations during the COVID-19 pandemic, this study engaged first-year engineering students in hybrid/blended teaching and learning activities at The Hong Kong Polytechnic University. By adopting hybrid/blended learning approaches we aimed to enhance students’ engagement and accomplish the intended learning outcomes in a flexible yet interactive learning environment. Basic concepts of Civil Engineering and Sustainable Development were introduced in the physical/digital classroom, where lectures were augmented by real-world examples. Interactive online discussion on crucial environmental and engineering issues was facilitated by course instructors and tutors with relevant expertise. Student-directed activities were emphasized to create an appropriate environment for students’ constructive and connective learning. Students’ perceptions regarding hybrid/blended teaching and learning approaches applied in this course were evaluated qualitatively and their feedback was collected through an institutional questionnaire survey. Survey results indicated a high satisfaction of the participating students regarding the course design, learning experiences, available resources, teaching arrangements, etc. Notably, students highly appreciated the encouraging and flexible approach of course instructors/tutors who stimulated their interest and motivation in self-directed learning and helped them to realize valuable learning experiences. Students’ positive perceptions in this course suggested that hybrid/blended learning approaches can be a fruitful strategy in higher education with potential integration into future curriculum design. Keywords: Higher education, hybrid/blended teaching pedagogy, face-to-face instruction, distance learning, digital classroom, COVID-19.
The Problem of Synthesis of Arts in the Context of the Development of Modern Ukrainian Painting on the Levkas.
Authors:   Kharkiv State Academy of Design and Fine Arts, Derihuz Natalia
Published: June 2023

Levkas painting is one of the most interesting contemporary art practices in Ukraine in the 21st century. It has great potential for creating of qualitatively and aesthetically new works and meanings. Today, we can observe the spread of levkas not only in the field of modern religious painting, but also among artists of other directions not only in Ukraine but also abroad. Levkas, as a structural component of the easel painting in the context of “synthesis of arts” acquires new qualities and meanings. The article considers the main interpretations of the concept of “synthesis of arts”, analyzes the main ways of combining arts by the criterion of integrating forces, identifies the main complicating factors, among which the main are: erroneous kinship and substantive diversity of terminology, insufficient research of the problems of synthesis in the context of painting on levkas. Also, the present study revealed the main characteristics of modern painting on levkas formation process, namely: partial loss of the sacred component and the formation of new stylistic, genre and technical-technological “canons”, the emergence of numerous replications based on the wide range of analog materials in the art market, finding new means of exposition and representation. In the course of the work the newest technical and stylistic means of artistic expression were established, which became the main tool in the process of modernization of levkas technique by synthesis, namely: the latest combinations of materials, options for expanding of levkas functions. Prospects for further research may include the following issues: consideration of the reasons for modernization of traditional painting on levkas, comparative analysis of the latest levkas mixtures, typology of existing works on levkas according to certain criteria and analysis of regional and chronological differences in modern levkas painting.
The Image of a City in Chinese Landscape Painting a Scientific Discourse in Chinese Historiography
Authors:   Kharkiv State Academy of Design and Arts, Liu Mingxuan
Published: June 2023

The article analyzes the phenomenon of the urban landscape, which is a notable phenomenon in modern Chinese art history. In this direction, the researchers consider not only the genre originality of the urban landscape, but also artistic models of the representation of the city image in painting. The urban landscape acquires independent forms within the framework of Chinese art through comparative practices of matching and comparison with Western artistic genesis. Already in the early 2000s, Chinese art historians were actively looking for new models for presentation of traditional art. At the same time, their desire to preserve traditional artistic achievements necessitated the identification of innovative and modern forms of Chinese art, which became notable artistic phenomena during the second half of the twentieth century. In Chinese “urban” painting, one of the central themes is the issue of modernization, which develops from two perspectives: a) urbanistic, which is aimed at the artistic generalization of various forms of urban life and landscape; b) in the direction of retro, which expresses a steady interest in the images of “old” China — urban landscapes and pictures of urban life, representing the aesthetics of the disappearance of traditional “small” China towns. For the current stage of development of fine arts in China, the image of the city in the context of regionalism and ethnic specificity is of great importance. The images of the city are directly related to the characteristic models of visual representation of the regions of China. Regions differ both in ways and norms of life (for example, small towns and conglomerate metropolitan areas) and in the variety of landscapes (for example, sea-side, mountain and plain). This factor is the cause of additional difficulties in defining the urban landscape as a genre of art. Certain features are analyzed on the example of the works of such outstanding masters of Chinese fine arts Yan Wanliang and Dai Shihe.
Vitamins and Minerals in Pregnancy Nutrition: Objections Management
Authors: Orlova S. V. , Nikitina E. A. , Balashova N. V. , Gribakin S. G. , Pigareva Yu. A.
Published: June 2023

Optimal nutrition, balanced in calories and containing all essential nutrients in adequate amounts, is an important condition for the proper fetus development and pregnancy complications prevention. Vitamins and minerals play an essential role in the regulation of metabolism, cell proliferation and differentiation, growth and development of the fetus. They also affect the mother’s body, preventing the development of pregnancy-related diseases. Despite the obvious need for vitamins and minerals for the health of the pregnant woman and the fetus, questions remain about the advisability of additional intake of certain micronutrients and their dosages during pregnancy. Our article is devoted to the analysis of recent data on the intake of vitamins A, D, folic acid, iron, calcium and magnesium during pregnancy and their effect on the fetus and mother.
An Arduino Based Cost Effective and Portable Luxmeter
Authors: POLAT Muhittin Yağmur , ÖZCAN Akın
Published: June 2023

Light is important physiological effects that determine the development of vegetation. Light intensity and measurements are important for agriculture and livestock. In this study, a cost effective and portable luxmeter was developed for agricultural purposes using Arduino and GY-30 sensor module and compared with a commercial device. The regression results between 0.945 and 0.969 (very high) obtained in study were in agreement with the recent studies It was understood that the developed system showed results compatible with commercial luxmeter devices.
MÍDIA, SOCIEDADE E CULTURA: CONEXÕES COM A OBRA BOM-CRIOULO
Authors:   UEMG - Universidade do Estado de Minas Gerais - Unidade Frutal, PESSOA MARCELO
Published: June 2023

A work like ours, intends, through such issues in evidence at the University, to draw attention to a latent cultural behavior of historical reversal of the segregation imposed on individuals who were formerly called “inadequate” (and who still cause astonishment today). The scientific intervention is justified by the fact that this theme calls us to see the field of consumption and social coexistence, whether through digital television inclusion, or through the consumerist path of pink money. As partial results, our research detects that in our society, there is a huge range of social representations on the subject, which forced us to make a second option for the same objects of analysis, that is, to put literary representation as a comparison route. and the media, proposing a dialogue between a conservative and archaic past and a supposedly liberal and avant-garde present. One of the theoretical pillars that support us is Freud's study, entitled "Three Essays on the Theory of Sexuality", together with Lacan's, in the seminar "Desire and its interpretation".