bluuebunny/crossref_metadata_2025 huggingface dataset:
Whole genome bisulfite sequencing of Medicago truncatula A17 wild type and lss mutants
Authors: Freese Nowlan H. , Schnabel Elise L. , Frugoli Julia A.
Published: March 2020

Objectives

Earlier work in our lab identified a spontaneous mutant (likesunnsupernodulator-lss) in Medicago truncatula, resulting in increased nodulation. Molecular genetic evidence indicated the phenotype was due to an unknown lesion resulting in cis-silencing of the SUNN gene. Altered methylation of the promoter was suspected, but analysis of the SUNN promoter by bisulfite sequencing at the time of publication revealed no significant methylation differences between the SUNN promoter in wild type and lss plants. Using advances in methylome generation we compared the methylome of wild type and the lss mutant in the larger 810 kB area of the genome where lss maps.

Data description

The data show the distribution of types of methylation across the entire genome between A17 wild type and lss mutants, the number of differentially methylated cytosines between genotypes, and the overall pattern of gene methylation between genotypes. We expect the wild type data will be especially useful as a reference for other investigations of methylation using M. truncatula.
Comprehensive mapping of the cell response to E. coli infection in porcine intestinal epithelial cells pretreated with exopolysaccharide derived from Lactobacillus reuteri
Authors: Tkáčiková Ľudmila , Mochnáčová Evelína , Tyagi Punit , Kiššová Zuzana , Bhide Mangesh
Published: March 2020

Bacterial exopolysaccharides (EPSs) are known to modulate immunity. To date, a plethora of studies have reported the effect of EPSs on intestinal cells; however few works have revealed a complete picture of the signalling events in intestinal epithelial cells induced by bacterial EPSs. Here, using transcriptomics, we comprehensively mapped the biological processes in porcine intestinal epithelial cells challenged with EPS derived from Lactobacillus reuteri alone, enterotoxigenic Escherichia coli (ETEC) or ETEC after pretreatment with EPS. The Gene Ontology analysis of differentially expressed genes (DEGs) showed that ETEC is able to evoke biological processes specifically involved in cell junction reorganization, extracellular matrix degradation, and activation of the innate immune response through the activation of pattern recognition receptors, such as TLRs and CTRs. A total of 495 DEGs were induced in ETEC-challenged cells. On the other hand, EPS pretreatment was able to attenuate overexpression of the genes induced by ETEC infection. The most relevant finding of this study is that EPS has a suppressive effect on the inflammatory response evoked by ETEC infection. On the basis of high-throughput RNA-seq, this report is the first to describe the effects of EPSs derived from L. reuteri used as a pretreatment of global gene expression in porcine epithelial cells.
Stationarity of aftershock activities of the 2016 Central Tottori Prefecture earthquake revealed by dense seismic observation
Authors: Iio Yoshihisa , Matsumoto Satoshi , Yamashita Yusuke , Sakai Shin’ichi , Tomisaka Kazuhide , Sawada Masayo , Iidaka Takashi , Iwasaki Takaya , Kamizono Megumi , Katao Hiroshi , Kato Aitaro , Kurashimo Eiji , Teguri Yoshiko , Tsuda Hiroo , Ueno Takashi
Published: March 2020

To clarify the relationship between earthquake occurrence and fluid, we analyzed data from a dense aftershock-observation network with 69 high-gain short-period seismographs installed immediately after the mainshock occurrence (October 21) in the aftershock area of the 2016 Central Tottori Prefecture earthquake. We determined the hypocenters and focal mechanisms of the aftershocks very precisely in the period from October 22 to December 15. We then investigated the temporal changes in the spatial distributions of hypocenters and T-axis azimuths of focal mechanisms. The distributions of aftershock hypocenters and T-axis azimuths are basically temporally stable, except those in limited portions in the shallow layer near the western edge of the aftershock area, where rapid decrease of aftershocks with T-axis azimuths of WSW to west was observed. If fluid rises from the lower crust due to fault rupture, the locations of aftershocks and focal mechanisms may change over time, especially in the deepest part of the aftershock region. However, the temporal change in these parameters was not apparent at depth. These observations suggest that the aftershock activity of the Central Tottori Prefecture earthquake was controlled mainly by stress concentration rather than strength reduction due to high fluid pressure.
Bailout procedures during percutaneous transluminal angioplasty of superficial femoral artery occlusive disease
Authors: Abd El-Mabood El-Sayed Afifi , Elkashef Omar Ahmed , Hosny Ahmed Samir , Zaghloul Hossam
Published: March 2020

Background

Though uncommon, complications of endovascular angioplasty and stenting may have devastating outcomes that can threaten limb and life. Adequate awareness of these complications will allow to achieve excellent clinical outcomes.

Results

Endovascular intervention was successful in treatment of most of distal SFA complications with limited use in flush ostial complications; residual stenosis ≥ 30%, flow-limiting dissection, perforation or rupture; 100% in group (2) vs 50% in group (1) but thrombosis; 75% of distal SFA lesions were treated endovascularly vs 40% of flush ostial lesions; X2 = 12.7, P = 0.02. Emergency surgery as a bailout was used for most ostial lesion complications: residual stenosis ≥ 30%, flow-limiting dissection, and perforation or rupture; 50% in group (1) vs 0% in group (2); X2 = 20.1, P = 0.01.

Conclusion

Bailout procedures are procedures used to save the limb or the patient. Evolving endovascular strategies embrace new technologies in an attempt to improve the safety and efficacy of revascularization procedures for lower extremity arterial occlusive disease.
Data-Driven Modeling of the Bicalutamide Dissolution from Powder Systems
Authors: Mendyk Aleksander , Pacławski Adam , Szafraniec-Szczęsny Joanna , Antosik Agata , Jamróz Witold , Paluch Marian , Jachowicz Renata
Published: March 2020

Low solubility of active pharmaceutical compounds (APIs) remains an important challenge in dosage form development process. In the manuscript, empirical models were developed and analyzed in order to predict dissolution of bicalutamide (BCL) from solid dispersion with various carriers. BCL was chosen as an example of a poor water-soluble API. Two separate datasets were created: one from literature data and another based on in-house experimental data. Computational experiments were conducted using artificial intelligence tools based on machine learning (AI/ML) with a plethora of techniques including artificial neural networks, decision trees, rule-based systems, and evolutionary computations. The latter resulting in classical mathematical equations provided models characterized by the lowest prediction error. In-house data turned out to be more homogeneous, as well as formulations were more extensively characterized than literature-based data. Thus, in-house data resulted in better models than literature-based data set. Among the other covariates, the best model uses for prediction of BCL dissolution profile the transmittance from IR spectrum at 1260 cm−1 wavenumber. Ab initio modeling–based in silico simulations were conducted to reveal potential BCL–excipients interaction. All crucial variables were selected automatically by AI/ML tools and resulted in reasonably simple and yet predictive models suitable for application in Quality by Design (QbD) approaches. Presented data-driven model development using AI/ML could be useful in various problems in the field of pharmaceutical technology, resulting in both predictive and investigational tools revealing new knowledge.
To Protect Health Care Workers Better, To Save More Lives With COVID-19
Authors: Chen Weiyun , Huang Yuguang
Published: March 2020

The coronavirus disease 2019 (COVID-19) pandemic has thus far caused a total of 81,747 confirmed cases with 3283 deaths in China and more than 370,000 confirmed cases including over 16,000 deaths around the world by March 24, 2020. This issue has received extensive attention from the international community and has become a major public health priority. As the pandemic progresses, it is regrettable to know the health care workers, including anesthesiologists, are being infected constantly. Therefore, we would like to share our firsthand practical experience and perspective in China, focusing on the personal protection of health care workers and the risk factors related to their infection, based on the different stages of the COVID-19 epidemic in China.
Existence and Non-Triviality of Equilibria in Economies with Default and Government
Authors: Orrillo Jaime , Filho Jolive de Santana Filho
Published: March 2020

This paper attempts  to accommodate the government into  Dubey, Geanakoplos and Shubik (2005) framework  in an explicit way, and proves that a non-trivial equilibrium  exists. By non-trivial equilibrium, we mean an equilibrium where there exists trading in the financial markets and some private borrower defaults.   The government,  characterised by its spending and tax  plans\footnote{Both are assumed to be exogenous like in Gale (1990).},  enters our economic model  by trading   financial assets  in order to balance  its budget. Proof of existence  is made by considering a generalised  game \`a la Debreu (1952)\footnote{Already well  known  in the GEI literature.}, and its  non-triviality  is obtained by using  the   non-differentiable optimisation theory.
The efficiency of risk sharing between UK and US: Robust estimation and calibration under market incompleteness
Authors: Fernandes Marcelo , Vieira Filho Jose Gil
Published: March 2020

We propose a novel estimator for the amount of international risk sharing that depends exclusively on asset returns data. In particular, our estimator has a nonparametric flavor in that it makes no parametric assumption on preferences and on the stochastic process that governs the dynamics of asset returns. This is in contrast with the existing estimators in the literature that either assume a specific utility function or that asset returns follow a geometric Brownian motion (GBM). Our estimates reveal there is less risk sharing between UK and US than one would find under the GBM assumption, though much more than what consumption data might suggest. Moreover, a simple calibration analysis shows that market incompleteness alone is enough to explain the difference between the consumption-based estimate of the risk-sharing index and ours.
The effective management of organizational and production structures
Authors: Loginovskiy Oleg , Gollay Aleksandr , Dranko Oleg , Shinkarev Aleksandr
Published: March 2020

The monograph is devoted to problems of increase of efficiency of management in the organizational and corporate structures. Issues of improving the management approaches in public authorities, industrial enterprises and corporations. The presented approaches, methods and models financial and economic condition of industrial companies, as well as the balanced development of technologies as the main means of increase of efficiency of their activities. Considerable attention is paid to the construction and development of corporate information systems.
For students and teachers, and anyone interested in the management of organizations.
Elaboração de paçoquinha com linhaça dourada
Authors: Crisóstomo Jany De Moura , Rodrigues Lays Arnaud Rosal Lopes , Santos Ana Caroline De Carvalho Albuquerque , Sousa Rosana Rodrigues de , Lavôr Layanne Cristina De Carvalho , Frota Karoline De Macêdo Gonçalves
Published: March 2020

Introdução: A linhaça dourada apresenta importantes quantidades de ácido α-linolênico, fibras solúveis e lignanas, podendo trazer benefícios para a saúde. Objetivo: Desenvolver paçoquinha adicionada de farinha de linhaça dourada (FLD) em diferentes proporções, bem como determinar sua composição centesimal e aceitação sensorial. Materiais e métodos: Foram elaboradas paçoquinhas com adição de 10%, 15% e 20% de FLD. A composição centesimal foi determinada e, após, foram aplicados testes de aceitação (escala hedônica). Os dados foram analisados através de teste de Kruskal Wallis e ANOVA, adotando-se nível de significância de 5%. Resultado: As paçoquinhas padrão e adicionadas de FLD não apresentaram diferença no teor de umidade (17,1 a 18,5%) e lipídeos (30,8 a 34,2%). Quanto ao teor de cinzas, apenas as formulações com 15 e 20% de FLD tiveram maior percentual, 1,94% e 2,03%, respectivamente. O teor de proteínas foi significativamente menor nas formulações com adição de linhaça (15,4 a 18,5%) e a quantidade de fibras alimentares aumentou nas formulações com FLD. Em relação à análise sensorial, as paçoquinhas adicionadas de FLD obtiveram boa aceitabilidade, não sendo observadas diferenças significativas com relação aos atributos avaliados em comparação com a paçoquinha padrão. Conclusão: Os dados obtidos permitiram verificar que é possível a substituição parcial do amendoim em paçoquinhas por farinha de linhaça dourada, pois os novos produtos apresentaram características sensoriais que agradaram aos consumidores em todos os atributos avaliados, além de apresentarem valor nutricional superior no que se refere ao incremento de fibras e teor de minerais.
GAME OF THRONES, INTERAÇÕES EM REDE E EXPERIÊNCIAS FORMATIVAS EM HISTÓRIA
Authors: D'Ávila Cristina , Santos Edméa , Macedo Társio Roberto
Published: March 2020

O presente artigo evidencia um conjunto de argumentos teórico-metodológicos que explicitam a relação entre a série televisiva Game of Thrones, as interações em rede e as experiências formativas em História no contexto da cibercultura. Dialoga-se com referencial teórico-metodológico multirreferencial que interage com experiências hermenêutico-formativas, mediadas por meio de interações ciberculturais em rede e suas ressonâncias no conhecimento-formação em História. Os fenômenos experienciados no campo de pesquisa confirmam que as redes assimilam e trabalham com um potencial lúdico-formativo a partir da heterogeneidade dos imaginários aprendentes e suas sensibilidades quando se pretendem formações em História.
TECNOLOGIAS DIGITAIS, LITERATURA INFANTIL E MULTILETRAMENTOS NA FORMAÇÃO DE PROFESSORAS
Authors: Fernandes Terezinha
Published: March 2020

O estudo objetiva compreender a relação entre literatura infantil e tecnologias digitais na obra literária A vida de Ada Lovelace discutindo insurgências, tensões e multiletramentos na formação de professoras que atuam com crianças. A pesquisa foi desenvolvida com inspiração na metodologia da pesquisa-formação, na disciplina de Múltiplas Linguagens: Literatura Infantil, em um curso de licenciatura de uma universidade pública federal, com duas professoras formadoras e doze orientadoras acadêmicas. Os resultados apontam as potencialidades da obra em análise tanto na formação de professoras, quanto no trabalho educativo com crianças por ser disparadora de reflexões sobre os entrelaçamentos entre Literatura infantil e tecnologias digitais e mobilizadora de diversos letramentos.
OS MOVIMENTOS CIBERATIVISTAS DE (RE)EXISTÊNCIA NAS REDES SOCIAIS E SUAS IMPLICAÇÕES PARA A EDUCAÇÃO
Authors: Couto Junior Dilton Ribeiro , Velloso Luciana , Dos Santos Rosemary
Published: March 2020

Com a emergência das possibilidades interativas engendradas pelo digital, deixamos de ser meros receptores de informação e passamos a ter a oportunidade também de produzir e compartilhar conteúdos diversos para outras/os internautas. Este novo contexto nos inspira a repensar o cenário político contemporâneo e os usos das tecnologias digitais, cuja especificidade na produção e no compartilhamento de dados informacionais rompe com a centralidade da mídia de massa. Diante disso, o presente artigo tem como objetivo investigar o ciberativismo de mulheres na rede social, focalizando os debates que emergiram em torno do movimento #ELENÃO, que envolveu a participação de milhões de internautas de todos os cantos do Brasil em setembro de 2018 em questionamento à campanha política do presidenciável Jair Bolsonaro. Esse movimento de (re)existência orquestrado por mulheres na rede traz implicações para o campo da educação, principalmente quando reconhecemos o Facebook enquanto um importante espaço de mobilização social.
#UERJRESISTE: a politização de si através das selfies
Authors: Carvalho Felipe Da Silva Ponte de , Pocahy Fernando
Published: March 2020

A rede social Facebook vem possibilitando aos usuárixs[1] de seu sistema a tematização das fotos de perfil - selfies — a partir de uma abertura a marcações de posicionamento político ou adesão a determinamos movimentos articulados a causas e/ou princípios éticos-políticos. A presente pesquisa busca compreender o modo como essas mobilizações politizadas de selfies se articulam nos cotidianos de sujeitos vinculados ao espaço acadêmico. Ao seguir xs nossxs interlocutorxs de pesquisa, conectamos vestígios de suas redes educativas, que por sua vez nos dão sinais de uma virada nos significados narcísicos e hedonistas, politizando suas selfies.[1] Pocahy (2019) vem fazendo o uso do sinal «x» como forma de colocar sob rasura noções consagradas e inflexões binárias de gênero. A noção de que certos conceitos, expressões, noções “[...]não servem mais – não são mais ‘bons para pensar’ – em sua forma original, não reconstruída”. (HALL, 2001, p. 104). Portanto, mais do que fazer caber múltiplos gêneros ou posições de sexualidade por meio de sinais como o próprio X ou @, *, #, _, ´e´ etc. tenta-se, com essa rasura linguística, evidenciar que a gramática marca a diferença. Não se trata de uma forma inclusiva, embora guarde essa potencialidade, mas justamente deseja-se expor que a linguagem não somente não é neutra, mas que corresponde a uma arena de disputa sobre regimes de visibilidade que se articulam vivamente na produção e na marcação da diferença. Ao mesmo instante, introduz-se aqui uma materialidade estética (estilística do signo e do sinal) que corresponde de uma disposição ética, abrindo os termos de uma agonística (política) da/na/com a língua. (POCAHY, 2019, p. 88).
A brief guide to telephone medical consultation
Authors: Iyengar Karthikeyan , El-Nahas Walaa
Published: March 2020

In certain situations it may not be possible to undertake a ‘face-to-face’ clinical hospital consultation. This comment provides a brief guide to undertaking an effective telephone hospital consultation that evolved during the current coronavirus outbreak while delivering a trauma and orthopaedic outpatient service.
Identification of active compounds and antioxidant activity of teak (Tectona grandis) leaves
Authors: Suryanti Venty , TRIANA KUSUMANINGSIH  , SOERYA DEWI MARLIYANA  , HILDA ALFIANI SETYONO  , ELYNA WAHYU TRISNAWATI
Published: March 2020

Abstract. Suryanti V, Kusumaningsih T, Marliyana SD, Setyono HA, Trisnawati EW. 2020. Identification of active compounds and antioxidant activity of teak (Tectona grandis) leaves. Biodiversitas 21: 941-947. Teak (Tectona grandis) grows in tropical area and the teak wood is widely used for building construction and furniture. Young teak leaf contains red pigment and often are used for natural food coloring. The research objectives were to isolate the young teak leaf chemical compounds and to investigate their antioxidant activities. The compounds identification was carried out by UV-Vis Spectroscopy, GC-MS and LC-MS. The antioxidant activity determination was carried out by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) method. The total phenolics content was determined using Folin-Ciocalteu method and total anthocyanins content was examined using the H-differential method. Two fractions were observed further by UV-Vis Spectroscopy, GC-MS and LC-MS. The UV-Vis spectrum of FA confirmed the presence of anthocyanins which has maximum absorbance at 208 and 492 nm. The GC-MS spectrum of fraction A (FA) revealed 4-hydroxy-4-methyl-2-pentanone, glycerin monoacetate, glycerin diacetate and 1-eicosanol. The UV-Vis spectrum of FC also confirms the presence of anthocyanins which has maximum absorbance at 489 nm. The LC-MS spectrum of fraction C (FC) shows anthocyanins, namely malvidin-3-o- (6-o-acetyl)-5-o-diglucoside. The FA and FC teak leaf fractions have strong antioxidant activities as their IC50 values are less than 50 ppm. Total phenolic of teak leaf extract was 6.17 mg GAE/g and total anthocyanins of teak leaf extract were 67.5 mg/L.
Ultrastructure of royal palm (Roystonea regia) leaf sheath
Authors: ULFA ADZKIA  , NARESWORO NUGROHO  , ISKANDAR Z. SIREGAR  , Karlinasari Lina
Published: March 2020

Abstract. Adzkia U, Nugroho N, Siregar IZ, Karlinasari L. 2020. Ultrastructure of royal palm (Roystonea regia) leaf sheath. Biodiversitas 21: 967-974. The royal palm (Roystonea regia (Kunth) F.Cook is one of the palm species that are many planted along the streets as part of urban landscapes. As biologically products, in nature they can self-cleaning with drop off their big leaves. The study aims to examine the morphological characteristics of ultrastructure and elemental content, crystallinity, as well as fibers derivation characteristics from the royal palm. The samples were taken out from leaf sheaths that divided into three sections along the width of i.e. outside, middle, and inside; in two conditions of leaf sheaths namely green and brownish-dry. The morphology structure and elemental content were observed by the Scanning Electron Microscopy (SEM) and the Energy Dispersive X-ray analysis (EDX), while the crystallinity was analyzed using X-ray diffraction (XRD), and fiber characteristics were measured to determine cell dimensions as well as to calculate Runkle ratio (RR), muhlsteph ratio (MR), coefficient of rigidity (CR), felting powder (FP), and flexibility ratio (FR). The diameter of palm fiber bundles was decreased from outside towards inside. The model of vascular tissue was rounded which located in the central region of the fiber bundles. The silicon content in the inside section was lower than those in the middle and outside sections. It was in line with the degree of crystallinity in the inside section which that higher than other sections. The highest degree of crystallinity was about 18 %. The fiber length of royal palm leaf sheath was in values around 6000 μm. However, the royal palm leaf sheath had thick fiber walls and thin lumen, as well as other fiber derivation characteristics of muhlsteph ratio, the coefficient of rigidity and the flexibility ratio, were in low-quality values. For that reason, the study provides information that the royal palm sheath was recommended as a composite reinforcing material.
The growth, pilodyn penetration, and wood properties of 12 Neolamarckia cadamba provenances at 42 months old
Authors: Nelly Anna  , Supriyanto  , Lina Karlinasari  , Dede J Sudrajat  , Iskandar Z Siregar
Published: March 2020

Abstract. Anna N, Supriyanto, Karlinasari L, Sudrajat DJ, Siregar IZ. 2020. The growth, pilodyn penetration, and wood properties of 12 Neolamarckia cadamba provenances at 42 months old. Biodiversitas 21: 1091-1100. Jabon (Neolamarckia cadamba (Roxb) Bosser) is a potential tree species for the development of plantation forests and community forests to supply timber demands. Information on the growth characteristics and wood properties of N. cadamba is important for the present and future development, yet. Those data is not available. This study aimed to assess the variations on growth (height, diameter), pilodyn (Pilodyn®) penetration, and physical properties of wood from core sample; and characterize the wood properties of 12 N. cadamba provenances at Parung Panjang, Bogor. The assessment of growth characteristics, pilodyn penetration, and physical properties of wood from core sample was carried out through census (1030 trees) on all provenance (using non-destructive method). The wood properties analysis was carried out using destructive method to one sample for each of the 12 N. cadamba provenances. Growth characteristics observed were the height (numerical scale pole), diameter (calipers), and pilodyn penetration. Meanwhile, the wood properties consisted of wood density, specific gravity, moisture content, fiber length (light microscope), MFA (x-ray diffraction), MOE, and MOR. The results showed that the correlation between the height and moisture content with pilodyn penetration was weak and positive, while the correlation between diameter, wood density, and specific gravity was weak and negative. The result of non-destructive test showed that Gowa provenance is superior. The results of destructive tests to investigate the wood properties of the twelve provenances showed that Batu Licin provenance is superior in terms of specific gravity and MOE, while Gowa provenance is superior in terms of MOR and fiber length. The results of the wood properties (i.e. density, specific gravity, moisture content, MOE, MOR, MFA, and fiber length) of the 12 N. cadamba provenances showed that the woods can be potentially used as non-structural materials only.
Harvesting trends of Amboina box turtles (Cuora amboinensis) seventeen years after listing in Appendix II CITES
Authors: Fauzi Muhammad Alif , Hamidy Amir , Kurniawan Nia
Published: March 2020

Abstract. Fauzi MA, Hamidy A, Kurniawan N. 2020. Harvesting trends of Amboina box turtles (Cuora amboinensis) seventeen years after listing in Appendix II CITES. Biodiversitas 21: 1142-1148. Among Southeast Asian freshwater turtles, the Amboina box turtle (Cuora amboinensis) held the highest recorded harvesting levels. The large volumes of harvesting influenced its International Union for Conservation of Nature (IUCN) revised the conservation status of C.amboinensis from Near Threatened to Vulnerable in 2000. The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) also inclusion of Amboina box turtle in Appendix II category. The CITES trade database provided a data set that tracks the legal trade of C. amboinensis in the global market from 2000 to 2017. Before 2005, Malaysia was the largest major supplier of this species to the global market. However, after 2005, Indonesia replaces Malaysia as the biggest exporter. From 2005 to 2014, the data showed that the trade trends already followed the quota of provisions. The trade routes of C amboinensis showed that the USA was the country to which these turtles were most frequently imported (50 times during 2000-2017), while China was still the biggest importer country in terms of quantity (463584 individuals from 2000-2017). The USA re-exported C. amboinensis for the pet trade to several European countries. Vietnam reportedly also re-exported C. amboinensis from Laos. However, Laos has rarely reported the occurrence of export activities to Vietnam. Based on these findings, we were able to understand the dynamics of the C. amboinensis trade globally more clearly, propose several actions deemed necessary for its conservation, and suggest greater on-going coordinated efforts to monitor the trade of this species.
Short communication: Effects of the various source areas of Indonesian bay leaves (Syzygium polyanthum) on chemical content and antidiabetic activity
Authors: Dewijanti Indah , MANGUNWARDOYO WIBOWO , ASTARI DWIRANTI  , MUHAMMAD HANAFI  , NINA ARTANTI
Published: March 2020

Abstract. Dewijanti ID, Mangunwardoyo W, Dwiranti A, Hanafi M, Artanti N. 2020. Short communication: Effects of the various source areas of Indonesian bay leaves (Syzygium polyanthum) on chemical content and antidiabetic activity. Biodiversitas 21: 1190-1195. Bay leaves (Syzygium polyanthum (Wight) Walp) are from an Indonesian plant species belonging to the Myrtaceae family. The Indonesian name for this plant is salam; it is found in Sumatra, Kalimantan, and the Java Islands. Its leaves are the part of the plant commonly used. Salam leaves are usually consumed by people as a food flavoring, but are also used as a traditional antidiabetic medicine. The purpose of this study was to discover the effects of salam leaves’ origins on their chemical content and antidiabetic activity. For this reason, salam leaf samples were collected from three different provinces in Java (West Java, Central Java, and East Java). The samples were extracted by boiling in water. Phytochemical screening, chemical analysis using TLC, HPLC, LC-MSMS, and FTIR, and antidiabetic in vitro testing using alpha-glucosidase inhibition methods were conducted on the salam leaves’ water extracts. The results showed that salam leaf extracts from all three provinces contained quercetin. However, the salam originating from East Java also contained coniferin, the salam from Central Java contained juncusol, and the salam from West Java contained retucine. The salam leaves originating from East Java showed the lowest antidiabetic activity, whereas salam leaf extract showed significantly higher antidiabetic activity. As conclusion, a plant’s growth origin affects its chemical content and antidiabetic activity.
Short Communication: DNA barcodes and phylogenetic of striped snakehead and ocellated snakehead fish from South Sumatra, Indonesia
Authors: Mochamad Syaifudin , MARINI WIJAYANTI  , SEFTI HEZA DWINANTI  , MUSLIM  , MUHAMMAD MAHENDRA  , SHELY MARLIANA
Published: March 2020

Abstract. Syaifudin M, Wijayanti M, Dwinanti SH, Muslim, Mahendra M, Marliana S. 2020. DNA barcodes and phylogenetic of striped snakehead and ocellated snakehead fish from South Sumatra, Indonesia. Biodiversitas 21: 1227-1235. This research aimed to identify the sequences of cytochrome c oxidase subunit I gene mitochondrial DNA (COI mtDNA), to construct a phylogenetic tree of striped snakehead (Channa striata) and ocellated snakehead (Channa pleuropthalma), and to measure water quality of Kelekar River, Indralaya, Ogan Ilir District and Danau Burung Besar River, Penukal Abab Lematang Ilir (PALI) District in South Sumatra, Indonesia. The research procedures consisted of DNA isolation, amplification by PCR (Polymerase Chain Reaction) and sequencing of fragment COI mtDNA. The length of nucleotide was 604 bp for striped snakehead and 587-604 bp for ocellated snakehead. Optimum annealing temperature was 500C for 15 seconds with 30 cycles. The result of BLAST analysis showed that striped snakehead from Kelekar and Danau Burung Besar River had 100% identity to striped snakehead from Java-Bali and furthest (97%) with striped snakehead from India. Ocellated snakehead had 100% similarity with the same species from Musi Banyuasin and Banjarmasin; and furthest (83%) with Channa limbata from Myanmar. Water quality in Kelekar River were temperature 31-31.60C, pH 4.76-4.96, dissolved oxygen 2.7-3.0 mg/L, ammonia <0.009 mg/L, total alkalinity 20 mg/L, and turbidity 62.5-63 cm. Meanwhile in Danau Burung Besar River showed temperature (29.3-30.70C), pH (3.6-6.7), dissolved oxygen (1.31-3.76 mg/L), ammonia (0.17-0.20 mg/L), and turbidity (50-90 cm).
Subaperture stitching interferometry based on the combination of the phase correlation and iterative gradient methods
Authors: Wang Ruoyan , Gao Zhishan , Zhu Dan , Liu Weijian , Ji Wen , Guo Zhenyan , Wang Dasen , Wang Lingjie , Xu Yao , Yuan Qun
Published: March 2020

Subaperture stitching interferometry (SAS) is an important method for map testing of large aperture optical components, in which a mechanical structure is often employed for the testing of each subaperture. By eliminating the phase deviation of the corresponding points in the overlapping regions of every adjacent subaperture, the whole aperture map can be obtained. Accurate subaperture positioning is an important guarantee for precise stitching. In this paper, a hybrid optimization algorithm is proposed to realize subpixel-level positioning accuracy in SAS based on the combination of the phase correlation and iterative gradient methods. The phase correlation method is adopted to calculate the pixel-level positioning deviation first, and the subpixel deviation is derived and then corrected by iterative optimization through the gradient method. The subpixel-level positioning accuracy of the proposed optimization algorithm is verified by simulations and a 76.2 mm off-axis parabolic mirror is chosen as an experimental testing sample. The surface map obtained from the proposed hybrid optimization method is consistent with the full aperture testing result, which also verifies that the proposed optimization algorithm is a powerful tool with subpixel-level positioning accuracy in SAS testing.
THz white light cavity with nonlinear dispersion in graphene
Authors: Zhou Wenpeng , Cai Yongqi , Zhao Shucai , Wang Peng , Li Dehua , Kolenderski Piotr , Peng Yandong
Published: March 2020

A white light cavity (WLC) scheme is proposed to achieve broadband response in the terahertz (THz) region by enhanced nonlinear dispersion in a magnetized graphene system. In the weak probe field limit, the cavity linewidth is narrowed due to electromagnetically induced transparency, and then it becomes nearly as broad as the empty-cavity linewidth under the condition of Autler–Towns splitting. It is interesting to find that the cavity linewidth can be further broadened by enhanced nonlinear dispersion. The simulation result shows that the response range of the cavity is from 6.273 THz to 6.308 THz under the given condition, which is nearly 11 times larger than the empty-cavity linewidth. Furthermore, the improvement in cavity transmission and the response of WLC at different frequencies are investigated.
Temporal dynamics of muscle optical properties during degeneration and regeneration in a canine muscle xenograft model
Authors: Nance Michael E. , Ravanfar Mohammadreza , Messler Mark , Duan Dongsheng , Yao Gang
Published: March 2020

We studied time-dependent changes in muscle optical properties during degeneration and regeneration using polarization-sensitive optical coherence tomography (PSOCT). Excised canine muscle transplants in a xenograft mouse model were imaged ex vivo from 3- to 112-day post-transplantation. PSOCT images were quantified to evaluate post-transplantation changes of three optical/structural properties: attenuation, birefringence and fiber alignment. The birefringence and fiber alignment decreased after transplantation until 20∼30-day and recovered thereafter. The attenuation coefficient showed a reversed trend over the same period of time. These results suggest that optical properties could be used for monitoring skeletal muscle degeneration and regeneration.
Design of photonic crystal nonlinear laser power limiter based on topological edge states and optical Kerr effect
Authors: Huang Jian , Lu Yuangang , Zhou Lang , Xu Feng , Zuo Dunwen
Published: March 2020

We propose a novel topological photonic crystal nonlinear laser power limiter based on topological edge states and optical Kerr effect. In the proposed laser power limiter, a one-dimensional photonic crystal in topological edge state allows the relatively weak signal light with a certain wavelength to pass through with high transmission, but blocks most of the intense hostile or accidental laser with the same wavelength due to the change of topological edge state generated from optical Kerr effect. Taking a 1064 nm wavelength as an example, we have designed such a nonlinear laser power limiter corresponding to the wavelength. When the optical power density is low (less than 0.12 MW/cm2), the light transmission can reach 82.54%, and the transmission can be reduced to 1.04% when the optical power density is increased to 11.66 MW/cm2. Therefore, this method provides a new promising approach to realize laser protection at the desired wavelength.
Optimal design of error-tolerant reprogrammable multiport interferometers
Authors: Fldzhyan S. A. , Saygin M. Yu. , Kulik S. P.
Published: March 2020

Photonic information processing demands programmable multiport interferometers capable of implementing arbitrary transfer matrices, for which planar meshes of error-sensitive Mach–Zehnder interferometers are usually exploited. We propose an alternative design that uses a single-static beam splitter (BS) and a variable phase shift as the building blocks. The design possesses superior resilience to manufacturing errors and losses without extra elements added into the scheme. Namely, the power transmissivities of the static BSs can take arbitrary values in the range from

≈

1

/

2

to

≈

4

/

5

. In this Letter, we show that the fraction of transfer matrices non-implementable by the interferometers of our design diminishes rapidly with its size.
Wide-angle wideband polarization-insensitive perfect absorber based on uniaxial anisotropic metasurfaces
Authors: Tseng Shi-Kang , Hsiao Hui-Hsin , Chiou Yih-Peng
Published: March 2020

A wide-angle, wideband, and polarization-insensitive metamaterial (MM) absorber was studied based on the theoretical concept of uniaxial perfect matching layer (UPML) in the terahertz range. The MM absorber was designed as a multi-layered anisotropic array structure consisting of a conductive VIA, a bi-layered slot-FSS, and a split-ring resonator (SRR) separated by porous silica spacers. Each component is optimized to approach the required macroscopic uniaxial property for satisfying the reflection-less boundary condition. The SRRs and VIAs were found to play an important role in maintaining large absorption when the angle of oblique incidence increases under transverse electric (TE) and transverse magnetic (TM) polarization, respectively. The absorption achieves 90% in the frequency regime of 0.9 to 10.5 THz, corresponding to a bandwidth of 168% to the central frequency, and retains such high performance up to 60° oblique incidence for both TE and TM waves.
Carnitine Diminishes Etoposide Toxic Action on Spermatogonial Self-renewal and Sperm Production in Adult Rats Treated in the Prepubertal Phase
Authors: Okada Fatima Kazue , Stumpp Taiza , Miraglia Sandra Maria
Published: March 2020

The aim of this study was to investigate carnitine action against negative effects of etoposide on stem/progenitor spermatogonia and on sperm production. Carnitine (250 mg/kg body weight/day) and etoposide (5 mg/kg body weight/day) were administered from 25-days postpartum to 32-days postpartum. Testes were collected at 32-days postpartum, 64-days postpartum, and 127-days postpartum, and submitted to the immuno-labeling of UTF1, SOX2, and PLZF proteins to identify undifferentiated spermatogonia populations. At 127-days postpartum, sperm were collected for analysis. Carnitine+etoposide group showed a higher numerical density of spermatogonia labeled for all studied proteins at 64-days postpartum (critical age) compared to the etoposide group. Moreover, there was an improvement of spermatic parameters and sperm DNA integrity in rats of the carnitine+etoposide group in comparison with rats of the etoposide group. The results suggest that carnitine improves the self-renewal of undifferentiated spermatogonia and promotes a partial protection on them, alleviating the etoposide harmful late effects and leading to an enhancement of the sperm parameters in adulthood:
Editorial
Authors: Valente Isabel Maria Freitas
Published: March 2020

https://doi.org/10.14195/1647-6336_21
Debating Privacy and ICT
Authors: Van Harten Dirk , Van Est Rinie
Published: March 2020

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Topological and Attribute Link Prediction using Firefly algorithm
Authors: Pulipati Srilatha , Ramakrishnan Manjula
Published: March 2020

Link prediction problem has received remarkable interest in recent past. In this paper, firefly swarm intelligence algorithm is used to perform link prediction exploiting the topological and node attribute features of social network. Fireflies will be made to traverse on nodes and edges of social networks and the brightness of fireflies will play a major role in their movement. Common neighbor method of link prediction is used to compute similarity score upon each iteration. Performance of the proposed algorithm were analyzed over standard data sets using validation method called ten-fold method. The accuracy of proposed work is measured in terms of Area Under the Curve Characteristics (AUC), Recall and Precision. Experimental results showed that the proposed work outperforms the methods proposed in the literature.
A role of heparan sulphate proteoglycan in the cellular uptake of lipocalins ß-lactoglobulin and allergen Fel d 4
Authors: Habeler Matthias , Lindner Herbert H. , Redl Bernhard
Published: March 2020

Lipocalins, small extracellular hydrophobic molecule carriers, can be internalized by a variety of different cells. However, to date receptors have only been identified for human lipocalins. Here, we specifically investigated uptake mechanisms for lipocalins ß-lactoglobulin and Fel d 4 in HeLa and Chinese hamster ovary (CHO) cells. We provide evidence that cell surface heparan sulphate proteoglycan is essential for internalization of these lipocalins. In HeLa cells, lipocalin uptake was inhibited by competition with soluble heparin, enzymatic digestion of cellular heparan sulphate by heparinase and inhibition of its biosynthesis by sodium chlorate. Biochemical studies by heparin affinity chromatography and colocalization studies further supported a role of heparan sulphate proteoglycan in lipocalin uptake. Finally, lipocalin uptake was blocked in CHO mutant cells defective in glycosaminoglycan biosynthesis whereas in wild-type cells it was clearly detectable. Thus, cell surface heparan sulphate proteoglycan represents a novel component absolutely participating in the cellular uptake of some lipocalins.
Precise point positioning with decimetre accuracy using wide-lane ambiguities and triple-frequency GNSS data
Authors: Deo Manoj , El-Mowafy Ahmed
Published: March 2020

This paper proposes precise point positioning (PPP) methods that offer an accuracy of a few decimetres (dm) with triple frequency GNSS data. Firstly, an enhanced triple frequency linear combination is presented for rapid fixing of the extra wide-lane (EWL) and wide-lane (WL) ambiguities for GPS, Beidou-2 and Galileo. This has improved performance compared to the Melbourne-Wübbena (MW) linear combination, and has 6.7 % lower measurement noise for the GPS L1/L2 signals, 12.7 % for L1/L5 and 0.7 % for L2/L5. Analysis with tested data showed a 5–6 % reduction in time required to fix the

N

21

{N_{21}}

and

N

51

{N_{51}}

ambiguities.

Once the EWL/WL ambiguities are fixed with the proposed linear combinations, three methods are presented that aim to provide positioning accuracy of a few dm. In the first approach, the three EWL/WL ambiguities in their respective phase equations are used to derive a low-noise ionosphere-free (IF) linear combination. The second method uses a low noise IF combination with two carrier-phase EWL/WL equations and a single pseudorange measurement. The third method uses a low noise IF combination with a single carrier phase EWL equation and two pseudorange measurements. These proposed methods can provide dm level positioning accuracy if carrier phase measurements with mm precision is tracked by the receiver. When comparing these combinations with a combination proposed in [22], it is found that superior performance is achieved with the third method when carrier phase noise is >5–6 mm for GPS and Beidou-2 and >2–3 mm for Galileo. This model only requires the EWL ambiguity to be fixed which typically takes just one epoch of data. Thus, the user achieves instant decimetre level PPP accuracy.
Chemical compounds, antioxidant activity, and in vitro and in silico litholytic effects of Zizyphus lotus extracts
Authors: Aya Khouchlaa , M’hamed Tijane
Published: March 2020

Background

The aim of this study was to evaluate the antioxidant activity and to determine the chemical compounds of organic extracts of fruits and leaves of Zizyphus lotus. The litholytic effect was determined on the basis of the in vitro effect of the aqueous extracts on the formation of crystals of stones. Finally, chemical compounds were investigated to identify their target using an in silico approach.

Methods

The antioxidant activity was determined with the diphenylpicrylhydrazyl radical trapping method. An aliquot of 2 mL of urine and 100 μL of an infusion of fruit and leaf aqueous extract of Z. lotus at different concentrations were used. The induction of calcium oxalate (CaOx) crystals was done by the addition of oxalic acid at 0.1 mol/L. The effect of aqueous extracts was compared with two inhibitors (citrate and magnesium) used as references. In silico modelization was carried out using SwissTargetPrediction.

Results

The antioxidant activity test showed that the methanol extract was active with an IC50 of 5 mg/mL. The aqueous extracts of fruits and leaves inhibit the formation of crystals of CaOx. Then, the composition of the methanol extracts of the leaves and fruits in high-performance liquid chromatography showed majority compounds such as quercetin-3-galactoside and hyperin. In silico assays showed that the identified molecules exert their effect by targeting enzymes responsible for calcium regulation, urate regulation, and maintenance of acid-base balance, and that had anti-inflammatory properties.

Conclusions

The present study showed that Z. lotus may be considered as a functional or nutraceutical food. However, further studies should be carried out in order to extract and purify these compounds to test their effect on urinary lithiasis.
Performance Comparison of Free-Space Optical (FSO) Communication Link Under OOK, BPSK, DPSK, QPSK and 8-PSK Modulation Formats in the Presence of Strong Atmospheric Turbulence
Authors: Sharoar Jahan Choyon A. K. M. , Chowdhury Ruhin
Published: March 2020

Free-space optical (FSO) communication system provides several advantages over radio frequency (RF) system offering high bandwidth, low cost, small space requirements and more secure transmission which is free from Electromagnetic Interference (EMI). However, when the transmitted light signal passes through the atmosphere it experiences attenuation and fluctuations due to atmospheric turbulence. This paper analyzes the bit error rate (BER) performance of FSO communication systems under strong atmospheric turbulence for on-off keying (OOK), binary phase-shift keying (BPSK), differential phase shift keying (DPSK), quadrature phase shift keying (QPSK) and 8-phase shift keying (8-PSK) for link distances of 500, 1,000, 1,500 and 2,000 m. The probability density function (pdf) of the received irradiance is modelled using the gamma-gamma distribution model. It is found that the system exhibits the best BER performance and compensates the lowest power penalty at BER of 10 - 9 for BPSK modulation compared with other modulation techniques which makes BPSK more appropriate to be used with FSO turbulent system.