bluuebunny/crossref_metadata_2025 huggingface dataset:
Freeze-Dried Cooked Chickpeas: Considering a Suitable Alternative to Prepare Tasty Reconstituted Dishes
Authors: Cambero M. Isabel , García de Fernando Gonzalo Doroteo , Romero de Ávila M. Dolores , Remiro Víctor , Capelo Luis , Segura José
Published: June 2023

The current trend in food consumption is toward convenience, i.e., fast food. The present work aims to study the potential of incorporating freeze-dried cooked chickpeas into a complex and traditional dish in Spanish gastronomy, such as Cocido, which has this legume as the main ingredient. Cocido is a two-course meal: a thin-noodle soup and a mix of chickpeas, several vegetables, and meat portions. The textural properties, sensory qualities, and rehydration kinetics of chickpeas of three Spanish varieties were investigated to select the most suitable cooking conditions to obtain freeze-dried chickpeas of easy rehydration whilst maintaining an adequate sensory quality for the preparation of the traditional dish. The sensory quality of various vegetables and meat portions, cooked under different conditions, was evaluated after freeze-drying and rehydration. It was possible to reproduce the sensory quality of the traditional dish after rehydration with water, heating to boiling in a microwave oven for 5 min, and resting for 10 min. Therefore, it is possible to commercialize complex dishes based on pulses and other cooked and freeze-dried ingredients as reconstituted meals with a wide nutrient profile. Nevertheless, additional research is required on the shelf life, together with other economic and marketing issues such as design of a proper packaging, that would allow consumption as a two-course meal.
Effects of Selenium Enrichment on Dough Fermentation Characteristics of Baker’s Yeast
Authors: He Ping , Zhang Mengmeng , Zhang Yizhe , Wu Hui , Zhang Xiaoyuan
Published: June 2023

In this research, the effect of selenium (Se) enrichment on dough fermentation characteristics of yeast and the possible mechanisms was investigated. Then, the Se-enriched yeast was used as starter to make Se-enriched bread, and the difference between Se-enriched bread and common bread was investigated. It was found Se enrichment increased CO2 production and sugar consumption rate of Saccharomyces cerevisiae (S. cerevisiae) in dough fermentation, and had positive impacts on final volume and rheological index of dough. The mechanism is possibly related to higher activity and protein expression of hexokinase (HK), phosphofructokinase (PFK), pyruvate kinase (PK), citrate synthase (CS), isocitrate dehydrogenase (ICD), and α-ketoglutarate dehydrogenase (α-KGDHC) in Se-enriched yeast. Moreover, Se-enriched bread (Se content: 11.29 μg/g) prepared by using Se-enriched yeast as starter exhibited higher overall acceptability on sensory, cell density in stomatal morphology, and better elasticity and cohesiveness on texture properties than common bread, which may be due to effect of higher CO2 production on dough quality. These results indicate Se-enriched yeast could be used as both Se-supplements and starter in baked-foods making.
Effect of Microwave Treatments Combined with Hot-Air Drying on Phytochemical Profiles and Antioxidant Activities in Lily Bulbs (Lilium lancifolium)
Authors: Quan Hong , Cai Yixi , Lu Yazhou , Shi Caifeng , Han Xinghao , Liu Linlin , Yin Xiu , Lan Xiaozhong , Guo Xinbo
Published: June 2023

Lily bulbs (Lilium lancifolium Thunb.) are rich in phytochemicals and have many potential biological activities which could be deep-processed for food or medicine purposes. This study investigated the effects of microwaves combined with hot-air drying on phytochemical profiles and antioxidant activities in lily bulbs. The results showed that six characteristic phytochemicals were identified in lily bulbs. They also showed that with an increase in microwave power and treatment time, regaloside A, regaloside B, regaloside E, and chlorogenic acid increased dramatically in lily bulbs. The 900 W (2 min) and the 500 W (5 min) groups could significantly suppress the browning of lily bulbs, with total color difference values of 28.97 ± 4.05 and 28.58 ± 3.31, respectively, and increase the content of detected phytochemicals. The highest oxygen radical absorbance activity was found in the 500 W, 5 min group, a 1.6-fold increase as compared with the control (57.16 ± 1.07 μmol TE/g DW), which was significantly relevant to the group’s phytochemical composition. Microwaves enhanced the phytochemicals and antioxidant capacity of lily bulbs, which could be an efficient and environmentally friendly strategy for improving the nutrition quality of lily bulbs during dehydration processing.
Effects of Policy Intervention on Food System Resilience to Emergency Risk Shock: Experience from China during COVID-19 Pandemic
Authors: Cui Mingjie , Zhang Xinhuan , Zhang Yufang , Yang Degang , Huo Jinwei , Xia Fuqiang
Published: June 2023

Achieving the goal of zero hunger within the goal of sustainable development requires improving the resilience of food systems to various types of risk shocks; food systems have shown significant vulnerability to COVID-19 outbreaks and transmission. By analyzing the impact of China’s lockdown policy and food security emergency policy in 2020 on food prices during the COVID-19 pandemic, we can clarify the role of policy intervention in enhancing the resilience of the food system, which can provide guidance, using China’s experience, for dealing with global food safety emergencies in the future. Firstly, we selected Beijing, Shanghai and Guangdong as food-consuming areas, and Shandong, Henan, and Hubei as food-producing areas. We also collected food security emergency policy data from the Chinese government website during the COVID-19 pandemic. Secondly, a difference-in-difference method was used to observe that Chinese cabbage and pork prices in the main food-producing areas and food-consuming areas rose more obviously after the adoption of lockdown policy, and Chinese cabbage and pork prices in the food-consuming areas increased more obviously than those in food-producing areas. However, staple food prices have not risen significantly. Thirdly, the response of four kinds of food prices to the food security emergency policy is analyzed quantitatively and graphically using the food price volatility index and food price increase rate; we observed that the response of food prices to the food security emergency policy is related to the food types and regions. For food types, the fluctuation degree and increase in Chinese cabbage and pork prices decreased significantly after the adoption of the food security emergency policy. For regions, when the food security emergency policy was adopted, the food prices in the main food-consuming areas fluctuated more obviously than those in food-producing areas. Finally, we found that the implementation of the transport policy and the joint supply emergency policy in the main producing and consuming areas has played a very significant and positive role in stabilizing food prices.
Factorized Doubling Algorithm for Large-Scale High-Ranked Riccati Equations in Fractional System
Authors: Yu Bo , Dong Ning
Published: June 2023

In real-life control problems, such as power systems, there are large-scale high-ranked discrete-time algebraic Riccati equations (DAREs) from fractional systems that require stabilizing solutions. However, these solutions are no longer numerically low-rank, which creates difficulties in computation and storage. Fortunately, the potential structures of the state matrix in these systems (e.g., being banded-plus-low-rank) could be beneficial for large-scale computation. In this paper, a factorized structure-preserving doubling algorithm (FSDA) is developed under the assumptions that the non-linear and constant terms are positive semidefinite and banded-plus-low-rank. The detailed iteration scheme and a deflation process for FSDA are analyzed. Additionally, a technique of partial truncation and compression is introduced to reduce the dimensions of the low-rank factors. The computation of residual and the termination condition of the structured version are also redesigned. Illustrative numerical examples show that the proposed FSDA outperforms SDA with hierarchical matrices toolbox (SDA_HODLR) on CPU time for large-scale problems.
Patient–Provider Health Communication Strategies: Enhancing HPV Vaccine Uptake among Adolescents of Color
Authors: Xu Mia Ann , Choi Jasmin , Capasso Ariadna , DiClemente Ralph
Published: June 2023

Cervical cancer remains a public health issue in the United States, particularly among stigmatized racial and ethnic populations. The human papillomavirus (HPV) vaccine has been clinically proven to prevent cervical cancers, and other HPV-associated cancers, among men and women. However, HPV vaccine uptake is suboptimal; only 55% of adolescents complete the two-dose series by age 15. Past research has shown that provider HPV vaccine communication for people of marginalized races/ethnicities is subpar. This article focuses on provider communication strategies to promote HPV vaccine uptake effectively and equitably. The authors reviewed the literature on evidence-based patient–provider HPV vaccine communication techniques to create a set of communication language providers could use and avoid using to enhance HPV vaccine acceptance and uptake among adolescents of marginalized racial and ethnic groups. Evidence has shown that information and the manner of dissemination are critical for influencing HPV vaccine uptake. These communication strategies must be suited to the context of the targeted population, and the message content can be broadly categorized into source, content, and modality. Strategies to improve patient–provider communication among adolescents of color using source, modality, and content include the following: (1) Source: increase provider self-efficacy to provide the recommendation, building rapport between providers and parents; (2) Content: persistent, forceful language with minimal acquiescence should be employed, reframing the conversation focus from sex to cancer; and (3) Modality: use multiple vaccine reminder modalities, and work with the community to culturally adapt the vaccination language. Utilizing effective behavior-change communication adapted for adolescents of color can reduce missed opportunities for HPV prevention, potentially decreasing racial and ethnic disparities in HPV-related morbidity and mortality.
Health-Related Behavior and Psychosocial Characteristics of Adolescent Female Smokers in Korea, Compared with Adolescent Male Smokers
Authors: Eo Yong-Sook , Lee Yeon-Hee , Kim Myo-Sung
Published: June 2023

This study aimed to investigate the relationship between health-related behavior and psychosocial characteristics among adolescent female smokers in South Korea using data from the 17th Korea Youth Risk Behavior Web-based Survey (KYRBWS) conducted in 2021. The analysis participants comprised 2407 adolescent smokers who were currently smoking, out of a sample of 54,835 participants. The characteristics of adolescent female smokers were examined by comparing them with those of adolescent male smokers. The results showed that male and female adolescent smokers accounted for 69.2% and 30.8% of the sample, respectively. Multiple logistic regression analysis identified school type, subjective socioeconomic status, physical activity, breakfast consumption, alcohol consumption, sexual experience, stress, generalized anxiety, and suicidal ideation as significant factors associated with adolescent female smokers. These findings provide important foundational data for the development of smoking-cessation programs and policies tailored specifically to adolescent female smokers.
Are All Child-to-Parent Violence Profiles Associated with Exposure to Family Violence? Findings from a Sample of Spanish Adolescents
Authors: Calvete Esther
Published: June 2023

Exposure to family violence (EFV) is proposed as a relevant antecedent of child-to-parent violence (CPV). However, both previous research and practitioner experience suggest that not all cases of CPV involve EFV. This study aimed to identify profiles of adolescents according to their degree of involvement in CPV and their EFV. A sample of 1647 adolescents (mean age = 14.30, SD = 1.21; 50.5% boys) completed measures of CPV, witnessing family violence, victimization by parents, permissive parenting, parental warmth, and several measures of cognitive and emotional characteristics. Latent profile analyses based on measures of CPV and family characteristics supported a four-profile solution. Profile 1 (82.2%) consisted of adolescents with very low scores on both CPV and exposure to family violence. Profile 2 (6.2%) was characterized by medium scores on psychological CPV and high EFV. Profile 3 (9.7%) was characterized by severe psychological CPV and very low EFV. Profile 4 (1.9%) included adolescents with the highest scores on CPV, including physical violence, and high EFV. These profiles were found to differ from each other according to several cognitive and emotional variables of the adolescents. Therefore, not all CPV profiles were associated with a history of EFV. The obtained profiles have implications for interventions.
Coping Strategies during Childbirth Related to Cultural Identity: Companionship, Choice of Analgesia and Maternal Satisfaction
Authors: Navarro-Prado Silvia , Sánchez-Ojeda María Angustias , Plaza del Pino Fernando Jesús , Vázquez-Sánchez María Ángeles , Tovar-Gálvez María Isabel , Azirar-Mohamed Nurimán
Published: June 2023

Childbirth is a biological process and how it is experienced and managed is influenced by numerous factors, among them, socio-cultural or health care received. Objective: The objective of this study is to ascertain whether cultural factors influence the way in which women deal with childbirth through the treatment of pain, companionship and maternal satisfaction. Methods: This study is a non-experimental, quantitative, ex post facto, cross-sectional study of women who gave birth in a border town in southern Spain. The sample consisted of 249 women. Results: No relationship was found between cultural factors and the choice of epidural analgesia, alternative methods to alleviate pain, being accompanied nor maternal satisfaction. There was a significant relationship between the type of companionship and with maternal satisfaction. Conclusions: Cultural factors did not influence how women dealt with dilation and childbirth. Results found that the person accompanying the mother was important for increasing maternal satisfaction. The intercultural training of healthcare professionals is necessary.
Perceived Importance of Metrics for Agile Scrum Environments
Authors: Almeida Fernando , Carneiro Pedro
Published: June 2023

Metrics are key elements that can give us valuable information about the effectiveness of agile software development processes, particularly considering the Scrum environment. This study aims to learn about the metrics adopted to assess agile development processes and explore the impact of how the role performed by each member in Scrum contributed to increasing/reducing the perception of the importance of these metrics. The impact of years of experience in Scrum on this perception was also explored. To this end, a quantitative study was conducted with 191 Scrum professionals in companies based in Portugal. The results show that the Scrum role is not a determining factor, while individuals with more years of experience have a higher perception of the importance of metrics related to team performance. The same conclusion is observed for the business value metric of the product backlog and the percentage of test automation in the testing phase. The findings allow for extending the knowledge about Scrum project management processes and their teams, in addition to offering important insights into the implementation of metrics for software engineering companies that adopt Scrum.
The Effect of Lure Position and Vegetation on the Performance of YATLORf Traps in the Monitoring of Click Beetles (Agriotes spp., Coleoptera: Elateridae)
Authors: Furlan Lorenzo , Bona Stefano , Tóth Miklós
Published: June 2023

Low-cost monitoring tools are needed to implement IPM in arable crops. YATLORf (Yf) traps baited with respective synthetic pheromone lures have proven to be a reliable tool for monitoring Agriotes spp., Europe’s most harmful soil pests. To optimize Yf use, we studied the effect of lure position in the trap and crop density on trap performance. Yf management detail was studied between 2000–2003 and 2014–2016 in various countries, with the traps being arranged in blocks. Each block contained one trap per treatment (i.e., lure position) under study. It was ascertained that lure attractant capacity can vary greatly with the lure’s position in the trap and the extent of vegetation. Information for making practical decisions is given. The ‘low’ lure position is suitable for all species in all field conditions, and is the best choice for A. brevis. Lures for A. brevis and A. lineatus need to be placed in the low position when the field has no or sparse vegetation cover. The ‘high’ lure position is unsuitable for A. brevis and A. obscurus, and should be considered for some species only. There are no restrictions on position for catching A. sordidus, i.e., any position is suitable. Dense vegetation (e.g., wheat) reduced the Yf trap’s potential for catching A. sordidus. Placing the trap just outside the field, or in a nearby field with bare/sparse vegetation, maintained the maximum catching potential. Vegetation density also influenced beetle sex ratio, with A. brevis and A. sordidus females always found in traps placed in fields with bare or low-density vegetation. Our findings have made it possible to obtain consistent monitoring outputs and to begin studies on multi-baiting the same trap, which can significantly reduce monitoring costs.
Lethal and Sublethal Effects of Contact Insecticides and Horticultural Oils on the Hibiscus Bud Weevil, Anthonomus testaceosquamosus Linell (Coleoptera: Curculionidae)
Authors: Greene A. Daniel , Yang Xiangbing , Velazquez-Hernandez Yisell , Vargas German , Kendra Paul E. , Mannion Catharine , Revynthi Alexandra M.
Published: June 2023

In 2017, the hibiscus bud weevil (HBW), Anthonomus testaceosquamosus Linell (Coleoptera: Curculionidae), was found outside of its native range of Mexico and Texas, infesting hibiscus plants in Florida. Therefore, we selected 21 different insecticide and horticultural oil products to evaluate their effects on the reproductive rate, feeding, and oviposition behavior of the HBW. In laboratory experiments, significant mortality was observed in adult weevils exposed to diflubenzuron-treated hibiscus leaves and buds, and hibiscus buds treated with diflubenzuron contained the fewest number of eggs and feeding/oviposition holes. Among horticultural oil products, significant mortality was only observed in experiments in which adult weevils were directly sprayed (direct experiments). Pyrethrins and spinetoram plus sulfoxaflor reduced the oviposition rate and caused significant mortality in direct experiments. Diflubenzuron, pyrethrins, spinetoram plus sulfoxaflor, and spirotetramat were further tested via contact toxicity experiments and greenhouse experiments. Contact toxicity experiments demonstrated that the tested insecticides (except diflubenzuron) were highly toxic to HBW adults. In greenhouse experiments, only those hibiscus plants treated with pyrethrins had significantly fewer feeding/oviposition holes and larvae within their flower buds when compared to control (water-treated) plants. These results constitute an important first step in the identification of effective chemical control options for the HBW.
Rationale and Design of a Randomized Controlled Clinical Trial on the Safety and Efficacy of Flecainide versus Amiodarone in the Cardioversion of Atrial Fibrillation at the Emergency Department in Patients with Coronary Artery Disease (FLECA-ED)
Authors: Tsioufis Panagiotis , Tsiachris Dimitris , Doundoulakis Ioannis , Kordalis Athanasios , Antoniou Christos-Konstantinos , Vlachakis Panayotis K. , Theofilis Panagiotis , Manta Eleni , Gatzoulis Konstantinos A. , Parissis John , Tsioufis Konstantinos
Published: June 2023

Pharmacologic cardioversion is a well-established alternative to electric cardioversion for hemodynamically stable patients, as it skips the risks associated with anesthesia. A recent network meta-analysis identifies the most effective antiarrhythmics for pharmacologic cardioversion with flecainide exhibiting a more efficacious and safer profile towards faster cardioversion. Moreover, the meta-analysis of class Ic antiarrhythmics revealed an absence of adverse events when used for pharmacologic cardioversion of AF in the ED, including patients with structural heart disease. The primary goals of this clinical trial are to prove the superiority of flecainide over amiodarone in the successful cardioversion of paroxysmal atrial fibrillation in the Emergency Department and to prove that the safety of flecainide is non-inferior to amiodarone in patients with coronary artery disease without residual ischemia, and an ejection fraction over 35%. The secondary goals of this study are to prove the superiority of flecainide over amiodarone in the reduction in hospitalizations from the Emergency Department due to atrial fibrillation in the time taken to achieve cardioversion, and in the reduction in the need to conduct electrical cardioversion.
A Personalized Approach to Determining the Caloric Needs of Children with Prader–Willi Syndrome Treated with Growth Hormone
Authors: Couto-Rosende Yolanda , Garcia-Tirado Diana , Palacio-Marco Mónica , Caixàs Assumpta , Corripio Raquel
Published: June 2023

Prader–Willi Syndrome (PWS) is the most frequent cause of genetic obesity. Early reports indicate that children with PWS require 20–40% fewer calories than healthy children to maintain adequate growth. Growth hormone treatment for children with PWS, approved in 2000, affects the body composition and probably affects energy requirements. This retrospective cross-sectional study analyzed the caloric intake in children with PWS aged from 6 months to 12 years old who underwent growth hormone treatment, comparing the patients’ caloric intake calculated from parent-recorded dietary intake versus the recommended caloric intake for healthy children, taking into account the age, sex, height, weight, and physical activity. We analyzed the data from 25 patients (13 (52%) boys; mean age, 6.72 ± 2.81 y; median age at starting growth hormone treatment, 1.4 y (IQR: 0.78–2.29); 17 (68%) normal weight and 8 (32%) overweight or obese). The mean daily energy intake was 1208 ± 186 kcal/d, representing 96.83% ± 18.66 of the recommended caloric intake for healthy children. The caloric intake in children with PWS treated with growth hormone was very similar to that recommended for healthy children; thus, we should rethink the dietary recommendations for these children.
Effect of Turmeric–Boswellia–Sesame Formulation in Menstrual Cramp Pain Associated with Primary Dysmenorrhea—A Double-Blind, Randomized, Placebo-Controlled Study
Authors: Agarwal Divya , Chaudhary Priyanka
Published: June 2023

Primary dysmenorrhea is a common menstrual disorder that significantly impacts women’s quality of life, productivity, and healthcare utilization. In this randomized, double-blinded, placebo-controlled trial, sixty women with primary dysmenorrhea were randomly divided into two groups with thirty participants each, and were allocated either turmeric–boswellia–sesame formulation (treatment) or placebo. The participants were advised to take two softgels of 500 mg as a single dose of allocated study intervention (total dose 1000 mg) when their menstrual pain reached 5 or more on a numerical rating scale (NRS). Menstrual cramp pain intensity and relief were evaluated every 30 min post-dose until 6 h. Results indicated a promising role of turmeric–boswellia–sesame formulation for menstrual pain relief compared to the placebo. The mean total pain relief (TOTPAR) of the treatment group (18.9 ± 0.56) was found to be 12.6 times better than the placebo group (1.5 ± 0.39). The NRS analysis showed that there was a statistically significant difference in pain intensity between the treatment and placebo groups (p < 0.001) at every timepoint. Additionally, the sum of pain intensity difference at 6 h (SPID6) of the treatment group (34.32 ± 1.41) showed a significant difference (p < 0.0001) and was 20.19 times better when compared to placebo (1.7 ± 0.56). Based on the study results, the turmeric–boswellia–sesame formulation exhibited remarkable menstrual pain relief as compared to the placebo.
Analysis of Short-Term Clinical and Functional Outcomes in Patients Undergoing Total Knee Arthroplasty with Kinematic Alignment Technique
Authors: Giorgino Riccardo , Nannini Alessandra , Scuttari Edoardo , Nuara Alessandro , Ciliberto Ricardo , Sosio Corrado , Sirtori Paolo , Peretti Giuseppe , Mangiavini Laura
Published: June 2023

Background: Surgery remains the best option for more advanced stages of knee osteoarthritis (OA). Kinematic alignment (KA) is an innovative surgical technique that aims to co-align the rotational axes of the femoral, tibial, and patella components with the three kinematic axes of the knee. This study aims to evaluate and analyze short-term clinical, psychological, and functional outcomes in patients undergoing total knee replacement with the KA technique. Methods: Twelve patients who underwent total knee replacement surgery with kinematic alignment from May 2022 until July 2022 were prospectively followed and interviewed. Before surgery, the day after surgery, and postoperative day 14, the following tests were evaluated: VAS, SF-12 PS, SF-12 MS, KSS, KSS-F, PHQ-9, and KOOS-PS. Results: The mean BMI value of 30.4 (±3.4) Kg/m2, mean age of 71.8 (±7.2) years. All the scores on the various tests administered consistently showed statistically significant improvement, not only immediately after surgery but also comparing the first to the fourteenth postoperative day. Conclusion: Kinematic alignment technique as a surgical treatment for KO allows the patient a fast postoperative recovery and good clinical, psychological, and functional results in a short time. Further studies are needed with a larger sample size, and prospective randomized studies are essential to compare these results with mechanical alignment.
Managing Labour in Women with COVID-19
Authors: Chilaka Victor Ngozi , Navti Osric , Opoku Albert , Okunoye Gbemisola O. , Babarinsa Isaac , Odukoya Olusegun Abiodun , Bako Abdulmalik , Sulaiman Abdul Kareem Pullatttayl , Mohan Manoj
Published: June 2023

Since first reported in December 2019 in Wuhan, China, COVID-19 caused by Severe Acute Respiratory Syndrome (SARS) Corona virus2 (SARS CoV-2) quickly spread to become a pandemic that has caused significant morbidity and mortality. The rapidity of the spread of the virus and the high mortality at the outset threatened to overwhelm health systems worldwide, and, indeed, this significantly impacted maternal health, especially since there was minimal experience to draw from. Experience with Covid 19 has grown exponentially as the unique needs of pregnant and labouring women with COVID-19 infection have become more evident. Managing COVID-19 parturients requires a multidisciplinary team consisting of anaesthesiologists, obstetricians, neonatologists, nursing staff, critical care staff, infectious disease and infection control experts. There should be a clear policy on triaging patients depending on the severity of their condition and the stage of labour. Those at high risk of respiratory failure should be managed in a tertiary referral centre with facilities for intensive care and assisted respiration. Staff and patients in delivery suites and operating rooms should be protected by enforcing infection protection principles such as offering dedicated rooms and theatres to SARS CoV-2 positive patients and using personal protective equipment. All hospital staff must be trained in infection control measures which should be updated regularly. Breastfeeding and care of the new-born must be part of the healthcare package offered to COVID-19 parturient mothers.
Finerenone: Questions and Answers—The Four Fundamental Arguments on the New-Born Promising Non-Steroidal Mineralocorticoid Receptor Antagonist
Authors: Di Lullo Luca , Lavalle Carlo , Scatena Alessia , Mariani Marco , Ronco Claudio , Bellasi Antonio
Published: June 2023

Chronic kidney disease (CKD) is one of the most common complications of diabetes mellitus and an independent risk factor for cardiovascular disease. Despite guideline-directed therapy of CKD in patients with type 2 diabetes, the risk of renal failure and cardiovascular events still remains high, and diabetes remains the leading cause of end-stage kidney disease in affected patients. To date, current medications for CKD and type 2 diabetes mellitus have not reset residual risk in patients due to a high grade of inflammation and fibrosis contributing to kidney and heart disease. This question-and-answer-based review will discuss the pharmacological and clinical differences between finerenone and other mineralocorticoid receptor antagonists and then move on to the main evidence in the cardiovascular and renal fields, closing, finally, on the potential role of therapeutic combination with sodium-glucose cotransporter 2 inhibitors (SGLT2is).
Conducting Polymer Nanocomposites for Electromagnetic Interference Shielding—Radical Developments
Authors: Kausar Ayesha , Ahmad Ishaq
Published: June 2023

Electromagnetic interference disturbs the working of electronic devices and affects the surroundings and human health. Consequently, research has led to the development of radiation-protection materials. Inherently conducting polymers have been found to be suitable for electromagnetic interference (EMI) shielding owing to their fine electrical conductivity properties. Moreover, nanoparticle-reinforced conjugated polymers have been used to form efficient nanocomposites for EMI shielding. Nanoparticle addition has further enhanced the radiation protection capability of conducting polymers. This state-of-the-art comprehensive review describes the potential of conducting polymer nanocomposites for EMI shielding. Conducting polymers, such as polyaniline, polypyrrole, and polythiophene, have been widely used to form nanocomposites with carbon, metal, and inorganic nanoparticles. The EMI shielding effectiveness of conducting polymers and nanocomposites has been the focus of researchers. Moreover, the microscopic, mechanical, thermal, magnetic, electrical, dielectric, and permittivity properties of nanocomposites have been explored. Electrically conducting materials achieve high EMI shielding by absorbing and/or dissipating the electromagnetic field. The future of these nanomaterials relies on nanomaterial design, facile processing, and overcoming dispersion and processing challenges in this field.
Short-Term Precision and Repeatability of Radiofrequency Echographic Multi Spectrometry (REMS) on Lumbar Spine and Proximal Femur: An In Vivo Study
Authors: Messina Carmelo , Gitto Salvatore , Colombo Roberta , Fusco Stefano , Guagliardo Giada , Piazza Mattia , Poli Jacopo Carlo , Albano Domenico , Sconfienza Luca Maria
Published: June 2023

To determine the short-term intra-operator precision and inter-operator repeatability of radiofrequency echographic multi-spectrometry (REMS) at the lumbar spine (LS) and proximal femur (FEM). All patients underwent an ultrasound scan of the LS and FEM. Both precision and repeatability, expressed as root-mean-square coefficient of variation (RMS-CV) and least significant change (LSC) were obtained using data from two consecutive REMS acquisitions by the same operator or two different operators, respectively. The precision was also assessed in the cohort stratified according to BMI classification. The mean (±SD) age of our subjects was 48.9 ± 6.8 for LS and 48.3 ± 6.1 for FEM. Precision was assessed on 42 subjects at LS and 37 subjects on FEM. Mean (±SD) BMI was 24.71 ± 4.2 for LS and 25.0 ± 4.84 for FEM. Respectively, the intra-operator precision error (RMS-CV) and LSC resulted in 0.47% and 1.29% at the spine and 0.32% and 0.89% at the proximal femur evaluation. The inter-operator variability investigated at the LS yielded an RMS-CV error of 0.55% and LSC of 1.52%, whereas for the FEM, the RMS-CV was 0.51% and the LSC was 1.40%. Similar values were found when subjects were divided into BMI subgroups. REMS technique provides a precise estimation of the US-BMD independent of subjects’ BMI differences.
Numerical Investigation of Self-Propulsion Performance and Noise Level of DARPA Suboff Model
Authors: Guo Chunyu , Wang Xu , Chen Chongge , Li Yinghong , Hu Jian
Published: June 2023

Propulsion noise is an enduring problem of significant military and environmental importance. Hence, it is crucial to investigate propeller noise characteristics. In this study, the hydrodynamic performance and noise level of the DARPA (Defense Advanced Research Projects Agency) Suboff submarine with the E1619 propeller were analyzed. The hull resistance and propeller hydrodynamics were studied separately, and the numerical results were validated using available experimental values. The self-propulsion point was determined by matching the hull resistance and propeller thrust following ITTC (International Towing Tank Conference) convention. Based on hydrodynamics and acoustic Ffowcs Williams–Hawkings (FW–H) models, the underwater-radiated noise characteristics in the self-propulsion state were simulated. The calculations indicated that the contribution of the quadrupole term in the FW–H equation is not negligible in the high-frequency band. Compared with the noise of open-water propellers, the spectrum of the E1619 propeller in its self-propulsion state is more complex, and the upstream noise is amplified.
Underwater Image Restoration Method Based on Multi-Frame Image under Artificial Light Source
Authors: Zhang Tianchi , Gao Yong , Wang Zhiyong , Zhang Mingjun
Published: June 2023

This paper studies the underwater image restoration problem in autonomous operation of AUV guided by underwater visual. An improved underwater image restoration method is developed based on multi-frame neighboring images under artificial light source. At first, multi-frame neighboring images are collected during AUV approaching the targets, and a transmittance estimation method is developed based on the multi-frame images to avoid the assumption of the known normalized residual energy ratio in the traditional methods. Then, the foreground and background regions of the images are segmented by locking the small area where the background light is located. Hence, the accuracy of background light estimation is improved for the underwater mages in turbid water to improve the accuracy of image restoration. Finally, the performance of the developed underwater image restoration method is verified by the comparative results in the pool environment.
Single-Setting 3D MRI/US-Guided Frozen Sectioning and Cryoablation of the Index Lesion: Mid-Term Oncologic and Functional Outcomes from a Pilot Study
Authors: Misuraca Leonardo , Lugnani Franco , Brassetti Aldo , Cacciatore Loris , Tedesco Francesco , Anceschi Umberto , Bove Alfredo Maria , D’Annunzio Simone , Ferriero Mariaconsiglia , Guaglianone Salvatore , Mastroianni Riccardo , Tuderti Gabriele , Panebianco Valeria , Sentinelli Steno , Simone Giuseppe
Published: June 2023

Our study explored frozen section reliability in prostate cancer (PCa) diagnoses and described surgical steps of a 3D magnetic resonance imaging (MRI)–ultrasound (US)-guided prostate biopsy (PB) and focal cryoablation of the index lesion (IL) in a single-setting procedure. Patients with a suspicious prostatic specific antigen (PSA) value, with a PIRADS 4 or 5 single lesion, were enrolled for trans perineal 3D MRI–US-guided PB and TRUS-guided focal cryoablation. Three cores were taken from the IL, three cores from the surrounding area, while systematic sampling was performed for the rest of the gland. After confirmation of PCa in frozen sections, focal cryoablation was performed. The 1st-year follow-up schedule included a PSA test at a 3-month interval, MRI 3 months and 1 year postoperatively and PB of the treated area at 1 year. Following the follow-up schedule, an involved PSA test at a 3-month interval and yearly MRI were performed. The PCa diagnosis was histologically confirmed in all three patients with frozen sections. At final histology, a single Gleason score upgrade from 6 (3 + 3) to 7 (3 + 4) was observed. All patients were discharged on postoperative day 1. At the 3-month evaluation, mean PSA values decreased from 12.54 (baseline) to 1.73 ng/mL and MRI images showed complete ablation of the IL in all patients. Urinary continence and potency were preserved in all patients. At the 1-year follow-up, one patient had suspicious ipsilateral recurrence on MRI and underwent a new analogous procedure. Post follow-up was uneventful and PSA remained stable in all patients. Three-dimensional MRI–US-guided frozen sectioning and focal cryoablation of the IL is a step forward towards a “patient-tailored” minimally invasive approach to the diagnosis and cure of PCa.
Impervious Surface Mapping Based on Remote Sensing and an Optimized Coupled Model: The Dianchi Basin as an Example
Authors: Li Yimin , Yang Xue , Wu Bowen , Zhao Juanzhen , Deng Xuanlun
Published: June 2023

Accurately extracting impervious surfaces (IS) and continuously monitoring their dynamics are crucial practices for promoting sustainable development in regional ecological environments and resources. In this context, we conducted experiments to extract IS of the Dianchi Lake Basin by utilizing various features extracted from remote sensing images and applying three different machine learning algorithms. Through this process, we obtained the optimal combination of features and a machine learning algorithm. Utilizing this model, our objective is to map the evolution of IS in the Dianchi Lake Basin, from 2000 to 2022, and analyze its dynamic changes. Our results showed the following: (1) The optimal model for IS extraction in the Dianchi Lake Basin was IMG-SPESVM based on the support vector machine, remote sensing images, and spectral features. (2) From 2000 to 2022, the spatial distribution and shape of the IS in the Dianchi Lake Basin changed significantly, but they all developed in the area around Dianchi Lake. (3) From 2000 to 2015, the rate of expansion of IS gradually accelerated, while from 2015 to 2022, it contracted. (4) From 2000 to 2022, the center of mass of IS moved to the northeast, and the standard deviation ellipse shifted greatly in the south–north direction. (5) Natural factors negatively affected the expansion of IS, while social factors positively affected the distribution of the IS.
Evolution of Floods: From Ancient Times to the Present Times (ca 7600 BC to the Present) and the Future
Authors: Angelakis Andreas N. , Capodaglio Andrea G. , Valipour Mohammad , Krasilnikoff Jens , Ahmed Abdelkader T. , Mandi Laila , Tzanakakis Vasileios A. , Baba Alper , Kumar Rohitashw , Zheng Xiaoyun , Min Zhang , Han Mooyoung , Turay Bashiru , Bilgiç Esra , Dercas Nicholas
Published: June 2023

Floods are one of the most dangerous natural disasters, causing great destruction, damage, and even fatalities worldwide. Flooding is the phenomenon of a sudden increase or even slow increase in the volume of water in a river or stream bed as the result of several possible factors: heavy or very long precipitation, melting snowpack, strong winds over the water, unusually high tides, tsunamis, or the failure of dams, gages, detention basins, or other structures that hold back water. To gain a better understanding of flooding, it is necessary to examine evidence, search for ancient wisdom, and compare flood-management practices in different regions in a chronological perspective. This study reviews flood events caused by rising sea levels and erratic weather from ancient times to the present. In addition, this review contemplates concerns about future flood challenges and possible countermeasures. Thus, it presents a catalogue of past examples in order to present a point of departure for the study of ancient floods and to learn lessons for preparation for future flood incidents including heavy rainfalls, particularly in urbanized areas. The study results show that ancient societies developed multifaceted technologies to cope with floods and many of them are still usable now and may even represent solutions and measures to counter the changing and increasingly more erratic weather of the present.
Influence of Agricultural Technology Extension and Social Networks on Chinese Farmers’ Adoption of Conservation Tillage Technology
Authors: Xu Jiabin , Cui Zhaoda , Wang Tianyi , Wang Jingjing , Yu Zhigang , Li Cuixia
Published: June 2023

Agricultural technology extension and social networks are the essential components of formal and informal institutions, respectively, and their influence on agricultural production has been the focus of academics. This article takes conservation tillage technology as an example, based on simple random unduplicated sampling, and uses survey data of 781 farmers in Heilongjiang, Henan, Shandong, and Shanxi provinces of China. This article empirically tests the interaction effects and heterogeneity of agricultural technology extension and social networks on farmers’ adoption of conservation tillage technology and analyzes their substitution effect or complementary effect. The results showed the following: (1) From a single dimension, both agricultural technology extension and social networks can significantly promote farmers’ adoption of conservation tillage technology, and the promotion effect of agricultural technology extension is greater. The average probability of farmers who accept agricultural technology extension and social networks adopting conservation tillage technology increases by 36.49% and 7.09%, respectively. (2) There is a complementary effect between agricultural technology extension and social networks in promoting farmers’ adoption of conservation tillage technology. The two functions complement and support each other, and this complementary effect is more evident in social networks’ reciprocity. (3) Further analysis reveals that the interaction effect between agricultural technology extension and social networks has significant group differences, technology type differences, and regional differences in farmers’ adoption of conservation tillage technology. Therefore, to facilitate the extension and application of conservation tillage technology, efforts need to be made in both agricultural technology extension and social networks, fully leveraging the complementary effects of the two. In addition, differentiated policies and measures should be adopted according to local conditions, and precise policies should be implemented for different groups and technologies.
Systemic Associations with Keratoconus
Authors: Unni Prasida , Lee Hyunjoo Jean
Published: June 2023

Keratoconus is a disease of the cornea that results in progressive steepening and thinning of the cornea and subsequent vision loss. It nearly always presents as a bilateral disease, suggesting that there is an underlying abnormality of the corneas that becomes manifest with time. However, the mechanisms underlying the development of keratoconus are largely unknown. Associations reported between keratoconus and systemic diseases are abundant in the literature, and the list of possible associations is very long. We found that atopy, Down syndrome, and various connective tissue diseases were the most frequently cited associations in our broad literature search. Additionally, Diabetes Mellitus has been increasingly studied as a possible protective factor against keratoconus. In this review, we have summarized the evidence for and against these particular systemic conditions and keratoconus and have discussed some of the implications of keratoconus patients having these conditions.
De Novo Synovial Chondromatosis following Primary Total Knee Arthroplasty: A Case Report
Authors: Braun Sebastian , Flevas Dimitrios A. , Sokrab Ruba , Ricotti Robert G. , Rojas Marcos Carolena , Pearle Andrew D. , Sculco Peter K.
Published: June 2023

In this case report, we present a rare case of a female patient who developed pain and swelling after a total knee arthroplasty. An extensive diagnostic workup including serum and synovial testing to rule out infection was performed in addition to advanced imaging including an MRI of the knee, but it was only after an arthroscopic synovectomy that the diagnosis of secondary synovial chondromatosis was confirmed. The purpose of this case report is to highlight the occurrence of secondary synovial chondromatosis as a rare cause of pain and swelling after total knee arthroplasty, thereby assisting clinicians in providing prompt diagnosis, surgical treatment, and efficient recovery in the setting of secondary synovial chondromatosis after total knee arthroplasty.
A New Type of Misaligned Journal Bearing with Flexible Structure
Authors: Jeon Woo-Ju , Hong Sung-Ho
Published: June 2023

A flexible structure is applied to improve the lubrication performance of a misaligned journal bearing. The journal bearing is a representative sliding bearing, and there is damage due to metal-to-metal contact as a result of misalignment. Since misalignment is an unavoidable phenomenon, a journal bearing with a flexible structure was proposed as a way to improve it. The lubrication characteristics of the bearing were evaluated numerically under a steady-state condition. EHL (elastohydrodynamic lubrication) analysis considering elastic deformation was performed. The lubrication performance was compared in accordance with variation of the geometry of the flexible structure and evaluated based on the minimum film thickness. Moreover, the results of the journal bearing with a flexible structure were compared with those of the journal bearing without the flexible structure. The flexible structure was then applied in the form of a groove to the area supporting high load on the journal bearing; it was elastically deformed by the generated oil film pressure, which helps obscure a larger oil film. Through numerical analysis, it was found that the journal bearing with a flexible structure can improve the lubrication performance in the misaligned condition.
Tribological Behavior of WS2 Nanoparticles as Additives in Calcium Sulfonate Complex–Polyurea Grease
Authors: Zhang Hong , Mo Yimin , Lv Juncheng , Wang Jun
Published: June 2023

In order to improve the tribological properties of calcium sulfonate complex–polyurea grease, WS2 nanoparticles were used as additives to prepare WS2 calcium sulfonate complex–polyurea grease. The tribological behavior of WS2 grease on the GCr15 surface was systematically studied. The results indicate that WS2 nanoparticles can significantly improve the extreme pressure performance of calcium sulfonate complex–polyurea grease. When the concentration of WS2 nanoparticles is 2 wt.%, the friction coefficient decreases by 14.94%, and the maximum nonseizure load PB increases by 31.41%. As the temperature increases, the friction coefficient and wear rate of WS2 grease first decrease and then increase. This is mainly attributed to the adsorption and frictional chemical reaction between WS2 nanoparticles and the matrix.