bluuebunny/crossref_metadata_2025 huggingface dataset:
Problems of preserving the right to freedom and personal integrity during criminal proceedings
Authors: Lazareva D.
Published: September 2022

The scientific article highlights the issue of observance of the right to liberty and security of person in criminal proceedings, given the difficulties in implementing the legal basis for ensuring this right by authorized officials. The procedural actions of observance of this right and their realization within the framework of the criminal process and the corresponding procedures provided by the current Criminal Procedure Code of Ukraine are comprehensively analyzed. Empirical analysis of all available materials by foreign and Ukrainian authors allows us to form realistic assessments of respect for the right to liberty and security of person. Methods of analysis, synthesis, deduction, ascent from the abstract to the concrete were used to carry out qualitative research. Restrictions on certain rights and freedoms, including the right to liberty and security of person, necessitate their observance in criminal proceedings. Recently, the legal community in this regard draws attention to the case law of the European Court of Human Rights, which is based on the provisions of the Convention, which in turn gives grounds to perceive this practice as an interpretation of standards of human rights and freedoms. The mechanisms of implementation of special procedures, such as: initiation of proceedings by the detainee regarding the validity of the detainee, have been studied. Forms of ensuring the right to liberty and security of person are derived. The right to liberty and security of person in the pre-trial investigation is ensured not only by the prosecution by virtue of the performance of their duties, but also by the defense, which is involved in a number of cases and is mostly involved by detainees, suspects interests during criminal proceedings. Thus, the legislator in Art. 206 of the CPC of Ukraine represents the presence of a lawyer as one of the forms of ensuring the right to liberty and security of person, which we have considered in a scientific article
Peculiarities of detention under martial law
Authors: Chernychenko I.V.
Published: September 2022

The article provides a systematic analysis of the changes to the criminal procedural legislation that came into force after beginning of the full-scale war in Ukraine. Most of the attention is drawn to Section II Chapter 18 "Precautionary measures, detention of a person" and Section IX1 of the Criminal Procedure Code of Ukraine "Special regime of pre-trial investigation, trial under martial law". Such precautionary measure as detention is the most popular and at the same time the most severe. The purpose of the article is to single out the peculiarities of the procedure for the application of detention under martial law and to analyze court decisions on this issue.One of the novelties was the possibility of choosing detention by the head of the relevant prosecutor's office when there is no objective possibility for the investigating judge to exercise his powers. Such precautionary measure can be chosen for a period of up to 30 days and extended up to one month repeatedly within the period of pre-trial investigation.The author paid special attention to the procedure for canceling a detention for military service under conscription during mobilization, for a special period. Based on the analyzed court practice, it was concluded that in many cases, the suspect or accused makes a request to the investigating judge, which is a violation of the established procedure. Because according to the Criminal Procedure Code of Ukraine only the prosecutor has the right to submit the petition to the investigating judge.In addition, the article highlights other features of detention under martial law: the possibility of automatic extension of term; choosing only detention for persons who are suspected or accused of committing certain types of crimes; the right to conduct a court hearing by videoconference in a case concerning an election or continuation of detention, even if the accused is outside the premises of the court and objects etc.
Justice as one of the key constitutional principles of regulation of the right to wages
Authors: Fridmanska V.I.
Published: September 2022

It is indicated that among the main constitutional principles that play a decisive role in the regulation of the right to wages are the principles of justice. The importance of the principle of justice as a fundamental principle is noted in the Charter of the United Nations (Article 1). Fair pay and a dignified human existence are also contained in the provisions of international treaties, including the Universal Declaration of Human Rights (Article 23), the International Covenant on Economic, Socialand Cultural Rights (Article 7), the European Social Charter (revised) ( Article 4), acts of the International Labor Organization.The attention is focused on the fact that the author does not agree with the statement that in Ukraine there is only legal consolidation of one sign of the content of the right to a fair wage - the establishment of the amount of remuneration at alevel not lower than the minimum wage established by law (art. 3 of the Law of Ukraine “On Remuneration”).It has been proven that the failure to directly enshrine the principle of justice in the Law of Ukraine “On Remuneration” does not mean that this principle does not apply to a number of legislative norms. Upon careful analysis of the above normative legalact, we came to the conclusion that the effect of the principle of justice was reflected in the following legal norms of the Law of Ukraine “On Remuneration”. In the opinion of the author, it is necessary to reflect the importance of the principle of justice in guaranteeing the right to wages. In the Basic Law, the last part of Article 43 guarantees the right to receive remuneration for work in a timely manner. We suggest that part 7 of Article 43 of the Constitution of Ukraine should be worded as follows: “Every person has the right to a decent and fair salary, which must be paid in full, in a timely manner, within the period established by law.”
Anadolu’da Bir Çepni Merkezi: 13-16. Yüzyıllarda Sinop ve Çevresinde Çepniler
Authors: YAVUZ Kamil
Published: September 2022

Anadolu’nun Türkleşmesi genel itibarıyla doğu-batı eksenli bir ilerleme çizgisine sahip olsa da Karadeniz’in Türkleşmesi söz konusu olduğunda bu ilerleme çizgisi geçerli değildir. Karadeniz’in Türkleşmesi Orta Anadolu’ya ulaşan Oğuz-Türkmen kitlelerinin Karadeniz kıyı hattına ilerlemesi sonucunda vadi boylarında müstahkem mevkilere kaleler ve savunma hatları inşa etmeleriyle Trabzon Rum İmparatorluğu’na karşı mevziler kazanmasıyla başlamıştır. Trabzon Rum İmparatorluğu’na karşı gaza alanı haline gelen Orta ve Doğu Karadeniz’de gazanın bayraktarlığını Oğuz/Türkmen grupları arasında ön plana çıkan Çepniler yapmıştır. Daha XIII. yüzyılın ortasından itibaren Orta Karadeniz’in önemli liman kentlerinden biri olan Sinop’a doğru hareket eden Çepniler, burayı Karadeniz savunma hattının merkezi müstahkemi ve ana askeri üslerinden birine dönüştürmüşlerdir. Böylece Trabzon Rum Devleti’ne karşı tazyiki arttırarak onlarla uzun soluklu bir mücadeleye girişmişlerdir. Zamanla bir kısmı Sarı Saltuk’la birlikte Kırım’a bir kısmı ise Trabzon Rum Devleti’nin sınırlarının doğuya çekilmesiyle Ordu-Giresun hattına göçtü. Buna rağmen Sinop ve havalisindeki Çepni varlığının gücü XV-XVI. yüzyılda da devam etmiştir. Bölgeye ait Osmanlı tahrir kayıtları bölgedeki Çepni varlığını güçlü bir şekilde ortaya koymaktadır. Bu çalışmada Çepnilerin Sinop merkezli gaza faaliyeti kısaca ele alınacak olup temelde Osmanlı tahrir defterlerindeki bilgilerden hareketle Sinop ve havalisinin Türkleşme sürecinde Çepnilerin rolü ele alınacaktır.
Deformalisasi kurikulum pendidikan Singapura dalam film How To Bury A Dead Cat
Authors: Setiawan Deddy
Published: September 2022

How To Bury A Dead Cat (2019) merupakan film pendek Singapura yang menjadi domain deformalisasi dari kurikulum pendidikan di Singapura. Film memiliki peran penting dalam mewujudkan fenomena, bagaimana deformalisasi kurikulum ini menghasilkan domain fenomena yang berbeda dari domain formal yaitu sekolah. Penelitian ini menjelaskan bagaimana film How To Bury A Dead Cat di bangun sebagai domain deformalisasi kurikulum pendidikan Singapura dan mengapa domain film ini menampilkan bentuk-bentuk deformalisasi dalam penyampaian tindakan berdasarkan kurikulum. Penelitian ini mengunakan analisis kualitatif pada media film Burhan Bungin dengan menggunakan analisis yang dipakai untuk meneliti suatu dokumen yang dapat berupa simbol, gambar atau sebagainya dalam memahami suatu konteks budaya atau konteks sosial tertentu. Analisis simbol dan gambar dan konteks sosial pada film How To Bury A Dead Cat menghasilkan penjelasan bahwa film kurikulum Civic and Moral Education (CME) terindikasi di dalam film sebagai bentuk aktualisasi dari rumah produksi dalam pembuatannya yang tak terlepas dari kebutuhan yang belum terpenuhi dari adanya kurikulum pendidikan di Singapura dalam menyampaikan pesan-pesannya. Lembaga produksi  atau rumah produksi yang membuat film juga memanfaatkan fenomena sosial yang terdapat di Singapura dan di lembaga pendidikan dan mengubahnya menjadi produk komoditi yang memiliki daya tukar. Hal ini juga membangun citra sebuah lembaga produksi yang bisa dipandang sebagai lembaga yang menyediakan domain deformalisasi pembelajaran formal yang dilakukan oleh sekolah.
The Impact of E-Banking Services on The Performance of Vietnamese Commercial Banks
Authors: Đinh Thị Thu Hồng , Nguyễn Hữu Tuấn , Trần Thị Hải Lý
Published: September 2022

Bài viết này phân tích ảnh hưởng của tăng trưởng dịch vụ ngân hàng điện tử đến hiệu quả hoạt động của các ngân hàng thương mại (NHTM) Việt Nam. Dữ liệu về số lượng máy thanh toán ATM và máy POS/EFTPOS/EDC, số lượng thẻ thanh toán, số dư tài khoản thẻ thanh toán và giá trị thanh toán qua thẻ được sử dụng để đo lường chỉ tiêu dịch vụ ngân hàng điện tử. Sử dụng kỹ thuật ước lượng mô hình phân phối trễ ARDL (autoregressive distributive lag) hiệu ứng cố định với dữ liệu bảng cân xứng của 10 NHTM cổ phần nội địa ở Việt Nam giai đoạn quý 1/2013 - quý 1/2021, chúng tôi tìm thấy dịch vụ ngân hàng điện tử có mối quan hệ ngược chiều với hiệu quả hoạt động của các NHTM trong mẫu quan sát. Phát hiện này khá ngạc nhiên và dường như ngược lại với kỳ vọng thông thường.
The Impact of The Covid-19 Pandemic on Vietnam’s Stock Market Volatility
Authors: Nguyễn Phan Thu Hằng , Lê Đình Nghi
Published: September 2022

Bài báo phân tích ảnh hưởng của COVID-19 đến độ biến thiên trên thị trường chứng khoán Việt Nam. Sử dụng dữ liệu ngày của chỉ số VN-Index từ 01/01/2016 đến 31/12/2021 và mô hình GARCH, kết quả nghiên cứu chỉ ra đại dịch COVID-19 làm gia tăng độ biến thiên trên thị thường chứng khoán Việt Nam, ngoại trừ làn sóng dịch thứ 3. Ngoài ra, bài báo còn chỉ ra độ biến thiên trên thị trường lớn nhất ở làn sóng dịch thứ nhất. Như vậy, các nhà đầu tư cần có các chiến lược đa dạng hóa danh mục đầu tư phù hợp nhằm quản trị rủi ro khi đầu tư trên thị trường chứng khoán Việt Nam trong bối cảnh đại dịch. Các cơ quan quản lý thị trường cũng cần có những biện pháp phù hợp nhằm quản trị rủi ro do sự biến động giá cổ phiếu trên thị trường, đảm bảo sự phát triển bền vững của thị trường khi dịch COVID-19 còn diễn biến phức tạp.
The Effect of Sensory Marketing on Perceived Service Quality and Satisfaction Toward Medical Service at Vietnam Public Hospital
Authors: Phạm Thị Huyền , Trần Quế Nhi , Doãn Hà My , La Gia Long , Vũ Tiến Đức
Published: September 2022

The article assesses the influence of sensory stimuli of patients who come for medical examination and treatment at Vietnam public hospitals on their perceived service quality and satisfaction through a survey of 619 people from in 52 provinces and cities. The results show that tactile, visual, olfactory, and taste stimuli significantly influence on perceived quality and customer satisfaction when experiencing public medical services. Some discussions and recommendations on applying sensory marketing to improve the perception and increase satisfaction toward quality of health services have been proposed, to improve the brand image of public hospitals as well as ensure the customer’s interests in terms of service quality. The study has reinforced previous studies and developed the Sensory Marketing model when assessing perceived quality and customer satisfaction
The Role of Government Support on SMEs Innovation: Evidence in Vietnam
Authors: Vũ Thị Hồng Nhung , Nguyễn Thị Hồng Hương
Published: September 2022

Using data from surveys of more than 2,000 firms each year in 2011, 2013, and 2015 and applying fixed effect estimation method, this study examines the effect of Government supporting programs on innovation engagement of small and medium enterprises (SMEs) in Vietnam. The findings show that the general Government supporting programs have a positive influence on the innovation improvement of SMEs. Among two main Government supporting programs including financial and technical support, the authors find that only technical supporting programs have significant positive effects on innovation engagement while financial assistance does not add significant benefits for SMEs.
Technical Efficiency Analysis of State-owned Enterprises using Popular Estimation Methods for Stochastic Frontier Models
Authors: Hoàng Thanh Hiền , Huỳnh Thị Diệu Linh
Published: September 2022

Technical efficiency (TE) is an important indicator to examine the performance of an enterprise. This paper applies the most popular stochastic frontier (SF) production functions to estimate the TE index for state-owned enterprises (SOEs) over the period 2010–2019. The results show that mean efficiency scores increased over the period 2010–2015, then decreased gradually in the period 2016–2019. Moreover, the analysis results by industry sectors also indicate that chemical manufacturing industry has the highest mean efficiency scores. Meanwhile, enterprises in the automotive and equipment manufacturing industries have the lowest technical efficiency, and the difference between these two sectors is up to 10%. The paper also makes some recommendations to policy makers to improve production efficiency in these firms.
Accounting Research in Vietnam: A Systematic Literature Review
Authors: Nguyễn Công Phương , Nguyễn Lan Phương , Trần Thị Thanh Thảo
Published: September 2022

The field of accounting research in Vietnam has only developed in the past ten years with the increasing number of studies. This paper analyses accounting studies in Vietnam by using a systematic literature review. Based on the databases of Vietnam Journal Online (VJOL), Vietnam Citation Gateway (VCGATE), and Google scholar, the authors collected 298 articles available in the area of qualified accounting published in the domestic scientific journals from 2004 to 2021. Using qualitative research methods through reading abstracts and systematic literature review, the results show that most of studies use the qualitative approach. Besides, among quantitative studies, the majority of studies use basic statistical techniques. The results also show that there has been a large increase in studies since 2015. The results give some implications for accounting research in the future.
The Relationship between Geopolitical Risk and Financial Stability of Commercial Banks in Asia
Authors: Lê Anh Tuấn , Phạm Thị Kiều Khanh
Published: September 2022

This research examines the influence of geopolitical risks on the financial stability of the banking system in Asian countries. Using a sample of 776 commercial banks in 8 Asian countries from 2006 to 2019, the authors find that geopolitical risk has a negative impact on bank stability. The research results are robust to the GMM estimation method to eliminate endogeneity caveats. The authors also employ interactive variables, which help reflect accurately the role of moderating factors such as bank size and the capital ratio on the association between geopolitical risk and bank financial stability. The test results show that the negative effect of geopolitical risk on bank financial stability is more severe in banks with small sizes and low capital rates.
Aplikasi Pelapisan Kitosan untuk Meningkatkan Umur Simpan Salak (Salacca zalacca)
Authors: Apriliyanti Erwidia Dwi , Purbasari Dian
Published: September 2022

Abstrak

Salak (Salacca zalacca) merupakan salah satu tanaman hortikultura asli Indonesia yang memiliki umur simpan yang pendek. Faktor yang mempengaruhi umur simpan buah salak adalah kontaminasi mikroorganisme, laju respirasi, dan transpirasi yang tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh pelapisan (coating) kitosan terhadap karakteristik mutu dalam meningkatkan umur simpan buah salak. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dua faktor yaitu perbedaan konsentrasi kitosan dan waktu penyimpanan dalam suhu ruang. Data dianalisis menggunakan Anova two mix factors dengan tes (?=0,05), jika diperoleh berbeda nyata maka dilakukan uji lanjut Duncan. Hasil penelitian menunjukkan susut bobot terendah pada konsentrasi kitosan 1% sebesar 10,8628%, kekerasan tertinggi  pada konsentrasi kitosan 1% sebesar 0,0971 N/mm2, nilai L tertinggi pada konsentrasi kitosan 1% sebesar 42,1744, nilai a tertinggi pada konsentrasi kitosan 0,5% sebesar 3,8944, nilai b tertinggi pada perlakuan konsentrasi kitosan 1% sebesar 9,7122 dan nilai Total Padatan Terlarut (TPT) terendah pada konsentrasi kitosan 1,5% sebesar 17,7000°brix

Abstract

Snakefruit (Salacca zalacca) is a horticultural plant native in Indonesia with a short shelf life. Factors affecting salak fruit's shelf life are microorganism contamination, respiration rate, and high transpiration. This study aims to determine the effect of chitosan coating on quality characteristics in increasing the shelf life of salak fruit. This study used a completely randomized design (CRD) with two factors: differences in chitosan concentration and storage time at room temperature. The data were analyzed using an ANOVA two mix factor with a test (? = 0,05), if it was found to be significantly different, Duncan's further test was carried out. The results showed the lowest weight loss at 1% chitosan concentration was 10,8628%, the highest hardness was at 1% chitosan concentration at 0,0971 N/mm2, the highest L value at 1% chitosan concentration was 42,1744, the highest a value was at concentration 0,5% chitosan was 3,8944, the highest b value at 1% chitosan concentration was 9,7122 and the lowest Total Dissolved Solids (TPT) was at 1,5% chitosan concentration at 17,7000°brix.
Treatment of Irritable Bowel Syndrome with Auricular Acupuncture: A controlled pilot study
Authors:   Italian Association For The Research And The Scientific Update, Lovato Antonello
Published: September 2022

AA is a viable treatment of IBS and Group B protocol could be a first approach of AA treatment in IBS. Nonetheless, protocol choice must be based more on results from clinical trials and less on theoretical AA reasoning
A Short Commentary on Physiotherapeutic Management of Temporomandibular Disorders in the United Kingdom: A Call to Holism and Compassion
Authors:   Nottingham University Hospitals, Weden Alexander
Published: September 2022

The ‘journey’ for such patients to find suitable care can be protracted thereby compounding the patients suffering and likely contributing to the embedment of the condition for the patient [7]. The provision of care for patients with a TMD within the UK can also be disparate leading to inconsistencies in care nationally creating a ‘post-code lottery’ and national inequity for patients seeking a solution or management of their TMD [7].
Research Advances of Traditional Chinese Medicine in the Treatment of Primary Open Angle Glaucoma
Authors:   Longhua Hospital Shanghai University Of Traditional Chinese Medicine, Zhang Yinjian
Published: September 2022

TCM takes clinical symptoms and signs as the treatment target. Under the guidance of the "overall concept" and "syndrome differentiation and treatment," the patient's condition was analyzed, and the appropriate treatment method was selected. TCM believes that the leading cause of POAG is stagnation of liver qi and retention of water. Therefore, the treatment of dispersing stagnated liver qi for relieving qi stagnation and eliminating water should be adopted.
Employer Brand and Application Intentions of Young People in Hanoi
Authors: Ngoc Thao Nguyen , Van Luan Hoang
Published: September 2022

Employer brand is becoming an important factor determining the effectiveness of attracting human resources, especially high-quality human resources of enterprises. Employer branding is built by businesses but its attractiveness is subjective to potential candidates in the specific economic, cultural and social context of the region and country. The article analyzes and inherits published studies to give the concept of employer brand and the elements constituting the remployer brand and the relationship between employer brand with the potential candidate's intention to apply for a job. Survey results on the evaluation of young people in Hanoi about the attractiveness of employer brands are compared with existing research results to show regional differences of employer brands. On the basis of research results, the article makes some conclusions and recommendations related to the construction and communication of employer brand in order to improve the effectiveness of attracting and maintaining human resources of the organization general and businesses in particular.

Keywords: Employer Brand, Intention to Apply, Young People in Hanoi, Employer Brand Development, Employer Brand Communication
Structural and Mechanical Properties of Cubic Silicon Nitride: A Molecular Dynamics Study
Authors: Thao Nguyen Thi , Ha Nguyen Thi Thanh , Van Vinh Le
Published: September 2022

Abstract: The molecular dynamics simulations have been used to study the microstructure as well as mechanical behavior of cubic silicon nitride (c-Si3N4) under the extended deformation. The silicon nitride sample was simulated under the cooling process and high pressure. At T=300 K, dominant nitrogen (N) atoms arrange into fcc lattice, and the rest of N atoms have hexagonal close-packed (hcp) and disordered structures. The hcp and disordered N atoms gather into the narrow bands. The phonon spectra of this sample are calculated and discussed. In this work we also present a molecular dynamics prediction for the elastic moduli in strained cubic silicon nitride as functions of the volumetric strain. Young’s modulus and Poisson’s ratio are also calculated for the  c-Si3N4.
PENGGUNAAN METODE RESITASI UNTUK MENINGKATKAN HASIL BELAJAR SISWA PADA POKOK BAHASAN EVOLUSI
Authors: Rachmayanti Rika
Published: September 2022

Tujuan penelitian ini adalah untuk mendeskripsikan penerapan metode Resitasi dalam meningkatkan hasil belajar mata pelalajaran Biologi pokok bahasan Evolusi. Sebagai subjek dalam penelitian ini adalah murid murid kelas XII MIPA 3 SMA Negeri 3 Cimahi tahun pelajaran 2019 - 2020 dengan jumlah murid sebanyak 38 orang. Sedangkan objek penelitian ini adalah penerapan metode Resitasi untuk meningkatkan hasil belajar mata pelalajaran Biologi. Sedangkan teknik pengumpulan data dalam penelitian ini dengan menggunakan teknik observasi, teknik tes, dan dokumentasi. Agar penelitian tindakan kelas ini berhasil dengan baik tanpa hambatan yang mengganggu kelancaran penelitian, peneliti menyusun tahapan-tahapan yang dilalui dalam penelitian tindakan kelas, yaitu: 1)Perencanaan/persiapan tindakan, 2) Pelaksanaan tindakan, 3) Observasi, 4) Refleksi dan Evaluasi. Temuan dalam penelitian bahwa penerapan metode Resitasi dapat meningkatkan hasil belajar siswa dari sebelum tindakan, siklus I, dan siklus II. Ketuntasan hasil belajar murid pada siklus I sebanyak 17 orang (44,7 %) yang belum tuntas dan 21 orang (55,3 %) siswa yang tuntas. Sedangkan pada siklus II yang belum tuntas 3 orang (7,9 %) dan yang tuntas melebihi 75 %, yaitu dengan ketuntasan sebanyak 35 orang murid (92,1 %) dari KKM yang telah ditetapkan, yaitu 77.Kata Kunci : Metode Resitasi, dan Hasil Belajar Biologi
ecos da repetição
Authors: Vargas Jean dos Santos , Santos Talita Leal
Published: September 2022

Considerando a relação ainda pouco conhecida entre Søren Kierkegaard (1813-1855) e Sigmund Freud (1856-1859), o objetivo deste artigo é pensar o horizonte do conceito de repetição enquanto problema filosófico e psicanalítico. A hipótese a ser argumentada aqui é que o pensador dinamarquês e o pai da psicanálise, embora não tenham de fato travado uma interação, lançam mão de ferramentas conceituais importantes para a psicanálise. Mostraremos como as reflexões de Kierkegaard e Freud, ora se aproximam, ora se distanciam. O artigo contribui, nesse sentido, tanto para se pensar em uma possível aproximação conceitual entre Kierkegaard e Freud, quanto para abordar um pano de fundo que trata da relação entre filosofia e psicanálise, na medida em que perpassa as discussões de ambos sobre o lugar da repetição. O pressuposto desta aproximação é a conjectura sustentada aqui que Kierkegaard antecipa no século XIX uma temática que seria retomada pela teoria psicanalítica no século seguinte. Pensaremos a perspectiva kierkegaardiana com a sua obra: A repetição, ao passo que em Freud frequentaremos as obras: Repetir, recordar e elaborar (1914) e Além do princípio do prazer (1920).
metafísica leibniziana e o ser para si na Ciência da Lógica de Hegel
Authors: Peralta Carlo Paim
Published: September 2022

O presente artigo trata do capítulo O ser para si da Ciência da Lógica de Hegel e do diálogo ali implícito com a filosofia leibniziana. No desenvolvimento da categoria do ser para si, que completa o movimento da qualidade e estabelece a transição para a quantidade na Doutrina do Ser da Ciência da Lógica, Hegel expõe a dialética entre o uno e o múltiplo, além de introduzir observações a respeito da filosofia leibniziana. O objetivo deste artigo é fazer uma apreciação dos capítulos Leibniz, das Lições Sobre a História da Filosofia, e O ser para si, da Ciência da Lógica, a fim de, relacionando-os, melhor compreender como a filosofia leibniziana é compreendida no contexto do ser para si, e como através deste Hegel pretende tê-la superado.
Evidências científicas das barreiras e ações à saúde do homem no contexto da Atenção Primária
Authors: Santos Elen Conceição da Costa , Dórea Franklin Silva , Souza Sailon Ribeiro de , Silva Guilherme Mota da , Santos Anna Cecília Soares , Andrade Ana Fátima Souza Melo de , Moura Emmanuelle Santos , Santos Tatyane Andrade dos , Sampaio Isabella Barros Almeida , Aragão Herifrania Tourinho
Published: September 2022

Objetivo: Descrever as barreiras e ações frente à promoção da saúde do homem na atenção primária, a partir das evidências científicas no periodo entre 2017 a 2022. Métodos: Trata-se de uma revisão integrativa do tipo qualitativa. A busca por artigos científicos ocorreu nas bases de dados Biblioteca Virtual de Saúde (BVS), SciELO e Portal de Periódico da CAPES. Os artigos da amostra final obedeceram aos critérios pré-estabelecidos, possibilitando a criação de duas categorias. Resultados: Dentre os artigos amostrais (10), apontou-se a existência de barreiras, em destaque as culturais, socioeconômicas, educacionais e burocráticas que dificultam a inclusão do homem no sistema de saúde público brasileiro. Ademais, estudos destacama importância das ações educativas como estratégias de comunicação com os usuários homens, para que sensibilizem e busquemos serviços ofertados na rede primáriade saúde. Todavia, requer do profissional de saúde, o enfermeiro, uma atuação holística e sistemática. Considerações finais: Nota-se que os enfermeiros são profissionais capacitados e habilitados para práticas que promovam o apoio e orientação a essa população, porém as barreiras na assistência integral à saúde do homem reforçam a necessidade de reformulações nas políticas públicas.
Ambiência do Centro Obstétrico de um hospital público do Distrito Federal: um relato de experiência
Authors: Soares Stephanea Marcelle Boaventura , Dantas Amanda Santos , Nascimento Amorabe dos Santos , Santos Bruna Cristina Costa dos , Ribeiro Júnior Atvaldo Fernandes , Campos Evertton Aurélio Dias , Anjos Jussara Soares Marques dos , Corrêa Thaís Helena da Costa , Ogliari Karina Brito da Costa , Ferreira Marcus Vinicius Ribeiro
Published: September 2022

Objetivo: Descrever, através de relato de experiência, a ambiência do Centro Obstétrico (CO) de um hospital público da Secretaria de Estado de Saúde do Distrito Federal (SES-DF).  Relato de experiência: As vivências no campo de estágio supervisionado II em atenção hospitalar no cenário do CO de um hospital público da região sul do Distrito Federal, entre os dias 1 a 14 de abril de 2022, realizadas por 3 acadêmicos de enfermagem na atuação na prestação da assistência e cuidados às pacientes gestantes, puérperas e recém-nascidos (RN’s) no Pré Parto, Parto e Pós-Parto (PPP), conforme preconizado na ementa do curso que aborda sobre a prestação de serviços de saúde nos diversos cenários de atuação da enfermagem, em níveis de atenção. Considerações finais: A vivência acadêmica no centro obstétrico possibilitou a execução de muitas abordagens práticas, principalmente no contato acerca da mulher num momento tão singular, pois, compreender o ambiente do CO permitiu uma ampliação dos conhecimentos teóricos que podem ser aprofundados para um maior domínio na atuação da enfermagem mesmo em cenários arcaicos e que marginaliza direitos.
Multifocal oligodendroglioma with callosal and brainstem involvement
Authors: Mubarak Fatima , Khandwala Kumail , Shamim Shahzad M. , Qureshi Madiha Bilal
Published: September 2022

Background:

Oligodendrogliomas are generally low-grade glial neoplasms commonly occurring in a cortical or subcortical location and frequently contain coarse calcifications. Tumors with 1p and 19q codeletions behave atypically and are more likely to have ill-defined margins and tend to have calcification. Very rarely, diffuse pattern and gliomatosis type of infiltrative nature of oligodendrogliomas have been described in sporadic case reports.

Case Description:

In this article, we present a case of a 31-year-old male who had diffuse multifocal oligodendroglioma with rare features of extensive callosal and brainstem involvement on imaging.

Conclusion:

Rare cases of oligodendrocytic gliomatosis cerebri or oligodendrogliomatosis with diffuse white matter spread of these tumors usually lead to a detrimental course of neurological status and a poor prognosis in these patients.
A rare case of metastatic colon cancer to the pineal region: A case report
Authors: Kawtharani Sarah , Moussalem Charbel , El Houshiemy Mohamad , Horanieh Elias , Najjar Marwan
Published: September 2022

Background:

Colorectal cancer is the third most common cancer and the third most leading cause of death in the United States with brain being a rare site for metastasis and the pineal region being a rarer site to manifest.

Case Description:

We present a rare case of a 72-year-old male patient with pineal region tumor and obstructive hydrocephalus for which an endoscopic third ventriculostomy was done with biopsy of the tumor showing primary colorectal origin in a patient known to be previously healthy.

Conclusion:

Intracranial metastasis to the pineal region is considered rare especially in cases without widely spread systematic cancer or without presence of other metastatic lesions in the brain. The case we presented suggests that we should consider pineal region metastasis as part of our differential whenever we encounter patients with an isolated pineal lesion. Endoscopic third ventriculostomy can be a better treatment option to treat obstructive hydrocephalus caused by the lesion potentially avoiding peritoneal dissemination.
Retro-odontoid pseudotumor presenting double layer on MRI: A case report
Authors: Kanematsu Ryo , Hanakita Junya , Takahashi Toshiyuki , Minami Manabu , Suda Izumi , Nakamura Sho , Takeuchi Shu , Tsujimoto Yoshitaka
Published: September 2022

Background:

Retro-odontoid pseudotumors (ROPs) typically present as a single mass posterior to the odontoid ranging from isointense to hypointense relative on T1-weighted magnetic resonance (MR) imaging (MRI T1WI). Here, a patient with ROP exhibited the double-layer sign on the MRI T1WI characterized by an initial ventral layer posterior to the odontoid process followed by a secondary dorsal layer.

Case Description:

An 84-year-old male presented with cervical myelopathy attributed to ROP resulting in atlantoaxial instability on dynamic X-ray studies, and the double-layer sign on the T1 MR accompanied by a cystic component. MR following C1–C2 posterior fusion, the patient’s myelopathy resolved and both layers spontaneously regressed on the follow-up MR studies.

Conclusion:

The MR-documented double layer sign with ROP, likely attributable to reactive hypertrophy of the transverse ligament with cystic components, may demonstrate spontaneous MR regression with symptom resolution following a C1–C2 posterior fusion.
Thoracic synovial cyst in patient with diffuse idiopathic skeletal hyperostosis
Authors: Takeuchi Shu , Hanakita Junya , Takahashi Toshiyuki , Kanematsu Ryo , Suda Izumi , Nakamura Sho , Minami Manabu
Published: September 2022

Background:

Spinal synovial cysts, attributed to degenerative changes of the facet joints, commonly occur at the sites of segmental spinal instability. Here, we present a patient with diffuse idiopathic skeletal hyperostosis (DISH) who developed a T10/T11 synovial cyst contributing to myelopathy that resolved following surgical cyst excision.

Case Description:

A 69-year-old male presented with progressive numbness and paraparesis for 2-month duration. The thoracic MR spine showed synovial cyst at the T10/T11 level, while the computed tomography confirmed DISH fusion between the T4 and T10 levels. Following a laminectomy with cyst excision, the patient’s symptoms resolved and he sustained no recurrent dynamic instability.

Conclusion:

A patient with DISH presented with the new onset of myelopathy attributed to a T10/T11 thoracic synovial cyst; following cyst excision, the patient’s myelopahty resolved.
Memprediksi Perilaku Penggunaan Kontrasepsi Menggunakan Theory Health Belief Model
Authors: Retno Heru Setyorini  , Utami Riadini Wahyu
Published: September 2022

Latar Belakang: Meskipun capaian Modern Contraceptive Prevelance Rate di Indonesia termasuk tinggi, akan tetapi unmet need masih menjadi sasaran yang belum sesuai dengan target yang telah ditetapkan. Hal ini masih menunjukkan rendahnya penggunaan alat kontrasepsi oleh wanita usia subur. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan penggunaan kontrasepsi. Metode: Penelitian cross sectional dilakukan dari Januari hingga Februari 2022 di Kecamatan Sewon Kabupaten Bantul. Data dikumpulkan dengan menggunakan kuesioner pada 116 wanita usia subur yang telah memiliki anak dan mempunyai media WhatsApp. Besar sampel dihitung dengan Software Raosoft Sample Size Calculator dengan derajat kepercayaan 95% dari 165 wanita usia subur. Hasil: Dengan menggunakan analisis jalur, dapat diketahui bahwa persepsi ancaman yang dirasakan berpengaruh secara langsung terhadap perilaku penggunaan kontrasepsi (b=1,26, CI 95%= 0,48 hingga 2,05, p=0,001). Persepsi keseriusan berpengaruh tidak langsung terhadap penggunaan kontrasepsi melalui persepsi ancaman yang dirasakan (b=2,14, CI 95%=1,12 hingga 3,15, p<0,001). Persepsi keparahan berpengaruh tidak langsung terhadap penggunaan kontrasepsi melalui persepsi ancaman yang dirasakan (b=1,98, 95% CI=,93 hingga 3,04, p<0,001). Simpulan: Diperlukan inisiatif untuk meningkatkan perilaku penggunaan kontrasepsi. Selanjutnya hasil temuan ini dapat dipertimbangkan dalam perumusan kebijakan pelayanan kesehatan untuk mengatasi masalah yang menjadi hambatan penggunaan kontrasepsi oleh wanita usia subur.
Faktor-Faktor yang Mempengaruhi Kualitas Hidup Lansia di Wilayah Kerja Puskesmas Gayamsari Kota Semarang
Authors: Fridolin Agnes , Musthofa Syamsuhuda Budi , Suryoputro Antono
Published: September 2022

Ketika seseorang memasuki usia lanjut, mereka akan mengalami perubahan fisik, kognitif dan psikososial. Sebagian besar lansia mempunyai masalah ketika mereka mulai menangani proses perubahan tersebut. Kebanyakan lansia sering mengalami kelemahan, hingga keterbatasan kemampuan. Akibat dari kondisi tersebut, kualitas hidup lansia menjadi kurang sehat. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor faktor yang mempengaruhi dari lanjut usia di Wilayah Kerja Puskesmas Gayamsari Kota Semarang. Penelitian ini mempunyai variabel independen yaitu faktor fisik, faktor psikologis, factor sosial dan factor lingkungan sedangkan variabel dependen adalah kualitas hidup. Desain penelitian ini menggunakan desain Cross Sectional. Populasi penelitian ini diambil dari lansia di Wilayah Kerja Puskesmas Gayamsari Kota Semarang, yang berjumlah 103 lansia yang telah memenuhi kriteria inklusi dan eksklusi. Data penelitian menggunakan jenis data kuesioner WHOQOL-BREF. Data tersebut dianalisa menggunakan uji regresi linear sederhana, dan ditampilkan dalam tabel distribusi dengan level signifikan d=0.05. Hasil penelitian ini menunjukan bahwa, ada pengaruh faktor fisik terhadap kualitas hidup (p=0.004), ada pengaruh factor sosial terhadap kualitas hidup (0.000).
State development bank of CHINA: Contribution to PRC sustainable economic growth
Authors: Matveevskii S. S. , Tazabaeva K. T.
Published: September 2022

The paper presents a description of the activities of the State Development Bank of China (GBRK). The author reveals the structure of the bank’s owners; GBRK mainly implements projects in the field of infrastructure, agriculture and industry, innovation both in China and abroad. The Bank finances its activities primarily through the issuance and sale of bonds. The growth of GBRK assets allows the bank to increase lending volumes, the number of financed projects. Most of the projects financed by the GBRC are being implemented in China; the bank is also actively working abroad: it participates in the import of minerals to China, and promotes the export of Chinese goods and services. The experience gained in the implementation of projects in China allows the bank abroad to successfully select projects, carry out their joint financing (taking into account local conditions). The strategically sound selection of projects, their successful implementation in key segments of the Chinese economy, and the growth of the bank’s assets determine the decisive contribution of the GBRC to China’s sustainable economic growth.
Institutional aspects of monetary policy formation: russian and foreign practice
Authors: Milkina I. V. , Lebedeva Yu. A.
Published: September 2022

In the article, the authors consider the issues of monetary policy as one of the main components of the economic policy of the state. A key role in the formation of monetary policy belongs to Central banks, which focus their activities on ensuring price or monetary stability, stability of the purchasing power of the national currency. The authors analyze the intermediate targets of monetary policy and its regimes carried out by economically developed countries of the world: monetary targeting, exchange rate targeting, inflation targeting or inflation targeting. An assessment is given of the Central Bank of the Russian Federation inflation targeting policy, which uses interest rate policy as the main instrument of monetary regulation, as one of the main channels of monetary policy impact on the economy, namely, changing the conditions for financing the real sector of the economy through the financial market.
Family violence in the new Russian realities: essence, types and reasons
Authors: Sadykov R. M. , Bolshakova N. L.
Published: September 2022

The article deals with the problem of domestic violence, which has its roots since ancient times and is quite common at the present time. The main types and forms of violence (physical, economic, sexual, psychological) are considered. In Russian society, women do not feel protected from the violence of spouses and other close relatives. In modern conditions, various forms of the use of force against women are common: domestic despotism, beatings, rape, sexual harassment. In many societies, family violence between a man and a woman is not perceived as a crime against society, but is a private matter of the family. It is believed that family members resort to physical violence in cases where they have no other opportunity to influence the family’s decision-making due to lack of authority. Psychological concepts have established a special role in the causes of violence of such factors as the weakening of instinctual control, frustration, aggressiveness, alcoholism, psychopathology. Sociological approaches focus on cultural norms that provoke violence, patriarchal social structure.
Transformation of the highest political elite in Russia after Peter the Great in the process of “palace coups”
Authors: Filimonov D. A.
Published: September 2022

The article is devoted to the study of the transformation of the highest political elite of the Russian Empire after the death of Peter the Great. This is one of the most difficult and dramatic periods in Russian history, called the era of “palace coups”. The main properties of the Russian political elite formed by the reforms of Peter the Great are analyzed, its main features are determined that influenced the nature of the intra-elite struggle and led to the transformation of the highest political elite in Russia. The composition and goals of the main court groups that fought for power under Catherine I, Peter II, Anna Ioannovna are considered in detail. The formation of such bodies as the Supreme Privy Council under Catherine I and the Cabinet of Ministers under Anna Ioannovna and their influence on ensuring the interests and transformation of the highest political elite are analyzed. Attempts to limit royal power by members of the Supreme Privy Council were considered and conclusions were drawn about the reasons for their failure.
Patterns of innovation networks formation in a closed-cycle economy
Authors: Shinkevich A. I. , Galimulina F. F. , Bashkirtseva S. A.
Published: September 2022

The relevance of the study is due to the poor knowledge of the problems of the formation of innovation networks in a closed-cycle economy. Against this background, the purpose of the study is determined – to develop provisions that develop the methodology of managing innovation networks in the context of a closed-loop economy and allow identifying patterns of formation of innovation networks. In this regard, attempts have been made to assess the patterns of development of network interactions within the framework of innovation activities of territories. Using the example of European countries, the interrelation of indicators of cooperation in the field of innovation and indicators of a cyclical economy is evaluated, as a result of which countries of advanced, transitional and catching-up types of development are identified. Based on the proposed author’s methodology, a matrix of positioning territories according to the degree of interconnection of innovation networks and closed-cycle economic indicators is constructed, 4 development trajectories are identified. The methodology for assessing the aggregate index differs by taking into account the reference proportions of cooperation, allows for a differentiated approach to the support of territories, is universal and can be applied by public authorities in the development and refinement of spatial development strategies.
Analysis of small molecule mixtures by super-resolved 1H NMR spectroscopy
Authors: Sinha Roy Aritro , Srivastava Madhur
Published: September 2022

Analysis of small molecules is essential to metabolomics, natural products, drug discovery, food technology and many other areas of interest. Current barriers preclude from identifying the constituent molecules in a mixture as overlapping clusters of NMR lines pose a major challenge in resolving signature frequencies for individual molecules. While homonuclear decoupling techniques produce much simplified pure shift spectra, they often affect sensitivity. Conversion of typical NMR spectra to pure shift spectra by signal processing without a priori knowledge about the coupling patterns is essential for accurate analysis. We developed a super-resolved wavelet packet transform based 1H NMR spectroscopy that can be used in high-throughput studies to reliably decouple individual constituents of small molecule mixtures. We demonstrate the efficacy of the method on the model mixtures of saccharides and amino acids in the presence of significant noise.
A Machine-learning-based Data Analysis Method for Cell-based Selection of DNA-encoded libraries (DELs)
Authors: Hou Rui , Xie Chao , Gui Yuhan , Li Gang , Li Xiaoyu
Published: September 2022

DNA-encoded library (DEL) is a powerful ligand discovery technology that has been widely adopted in the pharmaceutical industry. DEL selections are typically performed with a purified protein target immobilized on a matrix or in solution phase. Recently, DELs have also been used to interrogate the targets in complex biological environment, such as membrane proteins on live cells. However, due to the complex landscape of the cell surface, the selection inevitably involves significant non-specific interactions, and the selection data is much noisier than the ones with purified proteins, making reliable hit identification highly challenging. Researchers have developed several approaches to denoise DEL datasets, but it remains unclear whether they are suitable for cell-based DEL selections. Here, we propose a new machine-learning (ML)-based approach to process cell-based DEL selection datasets by using a Maximum A Posteriori (MAP) estimation loss function, a probabilistic framework that can account for and quantify uncertainties of noisy data. We applied the approach to a DEL selection dataset, where a library of 7,721,415 compounds was selected against a purified carbonic anhydrase 2 (CA-2) and a cell line expressing the membrane protein carbonic anhydrase 12 (CA-12). The Extended-Connectivity Fingerprint (ECFP)-based regression model using the MAP loss function was able to identify the true binders and also reliable structure-activity relationship (SAR) from the noisy cell-based selection datasets. In addition, the regularized enrichment metric (known as MAP enrichment) could also be calculated directly without involving the specific machine learning model, effectively suppressing low-confidence outliers and enhancing the signal-to-noise ratio.
Translating L-peptides into non-canonical linear and macrocyclic peptides
Authors: Mohapatra Somesh
Published: September 2022

Peptide-based drug discovery efforts has made significant advances in the recent past, enabling targeting of previously undruggable protein-protein interactions. Current efforts of high-throughput library screening involves L-peptide libraries, while non-canonical linear and macrocyclic peptides have been shown to be more metabolically stable, while having similar or higher biological activity. Here, we present a method to translate L-peptides into their non-canonical variants using a genetic algorithm-based approach. We optimize against a dual objective function of matching the chemical similarity of the mutated sequence to the reference L-peptide, and maximizing the binding affinity, characterized by the docking score against the target protein. We demonstrate the applicability of this method by discovering previously unknown non-canonical linear and macrocyclic peptides with high binding affinity against DRD2 kinase inhibitor. This work will provide a chemistry-informed approach for the discovery of non-canonical peptides from L-peptide library screening, thereby accelerating drug development efforts.