bluuebunny/crossref_metadata_2025 huggingface dataset:
Embeddedness in complex networks: Theoretical central debate, policy implications, and research agenda in ethnic entrepreneurship
Authors: Santos-Souza Humberto Reis dos , Azevedo-Ferreira Maxwel , Xavier Neto Oseas
Published: September 2024

Objective: This article explores ethnic entrepreneurship as an emerging organizational phenomenon, aiming to provide a comprehensive overview through a systematic literature review. Method: Triangulation employed bibliometric analysis, network analysis, citation and co-citation analysis, co-citation network, and a meta-analysis of bibliometrics over the period. It also includes content analysis demonstrating study characteristics, key findings, and suggestions for future research. Key Findings: The crucial role of ethnic networks in identity valorization and overcoming obstacles, exerting a moderating influence on entrepreneurial decisions, was identified. Furthermore, a broader theoretical framework for understanding the ethnic entrepreneurship phenomenon is synthesized. Theoretical/Methodological Contributions: A combined method of analyses is employed, offering an approach that can be adopted by similar research. The theoretical framework in which ethnic entrepreneurship studies are anchored is presented, emphasizing social immersion, co-ethnic network building, and Economic Sociology. Relevance/Originality: In a growing global migration movement, individuals have become entrepreneurs in the pursuit of ethnic valorization, equality, and survival. They face various barriers in host countries, influencing the decision to undertake entrepreneurship and their business. This study fills a gap by elucidating how research explains the interplay of these emerging phenomena. Social/Management Contributions: The article identifies future directions for ethnic entrepreneurship research, addressing crucial issues such as gender, network construction, financing, international refugee policies, public policies, ethnicity, ethnic markets, marginalization, and prejudice. Its conclusions offer valuable insights for managers, researchers, and policymakers.
A megszemélyesítés regiszterspecifikus mintázatai magyar nyelvű online sajtószövegekben
Authors: Simon Gábor
Published: September 2024

A tanulmány a magyar nyelv megszemélyesítő szerkezeteinek korpuszvezérelt elemzését mutatja be, két online sajtóregiszter specifikus mintázatainak összehasonlításán keresztül. A megszemélyesítő jelentésképzést a kognitív nyelvészet keretein belül értelmezi, részletezve a megszemélyesítések metonimikus jellegét. Az elemzés elsősorban a megszemélyesítő kifejezések korpuszbeli azonosítására épül, amelyet egy nemzetközi módszer magyarra adaptálásával és kiterjesztésével valósított meg a kutatás. A megszemélyesítések annotálása ebben az eljárásban kiterjed a perszonifikációban közreműködő szerkezettagok címkézésére, a köztük lévő szemantikai viszonyok jelölésére, valamint a megszemélyesítő jelentés lexikális szemantikai minőségének feltérképezésére. Az elemzés során magyar nyelvű online autótesztek és külpolitikai kommentárok összevetése történik, amelynek legfőbb eredményei a következők: (i) a megszemélyesítő kifejezések hasonló relatív gyakorisággal jelennek meg mindkét regiszterben, ugyanakkor (ii) a kommentárszövegek megszemélyesítései idiomatikusabbnak bizonyulnak, valamint (iii) a lexikális minőségben is statisztikailag szignifikáns különbségek mutathatók ki a két mintában.
Clinical characteristics, management, and survival of retinoblastoma patients: a five-year study at an Indonesian tertiary eye hospital
Authors: Putri Aliya Numasari , Kuntorini Maya Sari Wahyu , Amiruddin Primawita Oktarima
Published: September 2024

Background Studies on the clinical characteristics of retinoblastoma in Indonesia have been limited, even though retinoblastoma is the most common pediatric ocular malignancy worldwide and the second-most common pediatric malignancy in Indonesia. The estimated patient survival rate in lower-middle-income countries is 77%, and survival is highly dependent on early diagnosis and therapy.
Objective To identify the clinical characteristics of retinoblastoma in patients at the Cicendo National Eye Hospital, as an Indonesian tertiary eye hospital.
Methods This retrospective, observational study included pediatric patients <18 years of age diagnosed with retinoblastoma at the Cicendo National Eye Hospital, Bandung, West Java, between January 2018 and December 2022. We collected patients’ medical record data on age, gender, laterality, chief complaints, stage of disease, grouping, histopathologic features, therapy, and survival.
Results Of 247 retinoblastoma patients (328 eyes) enrolled, 53.85% presented at 1-2 years of age and 50.61% were males. Patients mostly presented with unilateral (67.21%) retinoblastoma, leukocoria (51.82%) as the chief complaint, and classified as International Retinoblastoma Staging System (IRSS) stage III (33.20%). Tumors were mostly intraocular (58.84%), particularly group E (39.02%). Most tumors showed undifferentiated (45.43%) and high-risk features (54.27%). Most eyes were treated with combination therapy (74.09%), particularly local and systemic therapy (59.45%).  Survival was noted at 18.62% of patients, but 62.75% of patients were lost to follow-up.
Conclusion Most patients present with advanced retinoblastoma. Most histopathological results shows undifferentiated and high-risk features of the tumor. Delays in diagnosis and therapy may occur due to a lack of awareness and knowledge regarding clinical manifestations of retinoblastoma, which leads to worse prognosis.
The role of early aggressive nutrition on growth of very preterm or very low birth weight infants
Authors: Insani Nadia Dwi , Rohsiswatmo Rinawati , Sjarif Damayanti Rusli , Marsubrin Putri Maharani Tristanita , Yuliarti Klara , Gultom Lanny Christine
Published: September 2024

Background Very preterm infants (<32 weeks gestational age) are at high risk of poor neurodevelopmental outcomes. Early aggressive parenteral nutrition (protein ³ 2g/kg/day) can reduce the incidence of malnutrition in very preterm infants. At present, Fatmawati General Hospital does not have a standard nutritional protocol for preterm infant.
Objective To determine the difference in growth (days to regain birth weight and growth velocity) of very preterm (<32 weeks gestational age) or very low birth weight (VLBW) (<1500g) infants who were born and hospitalized in the Neonatal Unit of Fatmawati General Hospital, Jakarta, before and after applying early aggressive parenteral nutrition using a nutrition protocol from Cipto Mangunkusumo Hospital, Jakarta.
Methods A quasi-experimental study was conducted on 23 very preterm or VLBW infants in the Neonatal Unit of Fatmawati General Hospital, from July to November 2019. Control group data were taken from medical records of very preterm or VLBW babies discharged from our unit from January 2018 – to June 2019 and compared to those of the intervention group.
Results The intervention group regained their birth weight significantly faster than the control group [mean 7.43 (SD 3.5) vs. 16.73 (SD 5.1) days, respectively; (P=0.00)]. Mean growth velocity was also significantly higher in the intervention group than in the control group [14.6 (SD 6.0) vs. 8.9 (SD 6.9) gram/kg/day, respectively; (P=0.002)].
Conclusion Provision of early aggressive parenteral nutrition reduces the time to regain birth weight and leads to higher growth velocity in very preterm/VLBW infants.
Effectiveness of a short, intensive, art-based group intervention on attention level in children with autism spectrum disorders: a pre-post experimental study
Authors: Abdulah Deldar Morad , Abdulla Bayar Mohammed Omar , Liamputtong Pranee
Published: September 2024

Background The rate of autism spectrum disorder (ASD) is dramatically rising globally, especially in the Middle East and North Africa. There has been little research on the effects of art-based interventions on attention impairments among children with ASD.
Objective To examine the effectiveness of a short, intensive, art-based intervention on attention switching and attention to detail in children with moderate-severe ASD.
Methods In this pre- and post-experimental study, children previously diagnosed with levels 2 and 3 ASD were invited to join a one-month, art-based course. The art-based intervention was held 3 days/week for 2 hours per day.
Results The mean age of subjects was 8.33 (range 5 to 11) years; there were 10 (83.33%) males and 2 (16.67%) females. The total Autism Spectrum Quotient (AQ-Child) scores from baseline to one week after completion of the art-based course were not significantly different. In addition, mean social skills scores of attention switching and attention to detail, as well as communication scores were not significantly changed from baseline to after course completion. However, the children had significantly worse median imagination scores after the course compared to baseline scores (18.0 vs. 16.0, respectively) (P=0.0020).
Conclusion After a one-month, art-based, group intervention, AQ-Child scores did not change significantly in total score, social skills, attention switching, attention to detail, or communication. The median imagination score worsened after, compared to before, the intervention. However, these results need to be interpreted with caution due to the very small sample size.
Comparison of oral caffeine and oral theophylline for apnea of prematurity: A randomized clinical trial
Authors: Anggrainy Nensy , Sarosa Gatot Irawan , Suswihardhyono Adhie Nur  Radityo
Published: September 2024

Background Caffeine and theophylline are methylxanthine compounds that have been widely used in the treatment of apnea of prematurity (AOP). Previous studies comparing the two agents have shown inconsistent results and have mostly used intravenous preparations.
Objective To assess the effectiveness of oral administration of caffeine compared to oral theophylline as therapy for apnea of prematurity.
Methods Fifty consecutively recruited premature neonates (gestational age 28-34 weeks, birth weight <2,500 g) with AOP who were able to tolerate at least 10 mL/kg of enteral feeding were randomized to receive either oral caffeine or oral theophylline for seven days. The main outcome was the daily frequency of apnea after treatment. Secondary outcomes were duration of oxygen or CPAP administration, duration of oxygen fraction (FiO2) taper to reach 21%, time to achievement of full feeding tolerance, length of hospital stay, and side effects.
Results We randomized 25 subjects into each group. The distribution of baseline characteristics (gender, gestational age, mode of delivery, birth weight and length, age at onset of AOP, and initial frequency of AOP) was similar between both groups. The mean daily number of apnea episodes after treatment was significantly higher in the caffeine group compared to the theophylline group [3.16 (SD 1.31) vs. 2.28 (SD 1.40); P=0.031]. The caffeine group, compared to the theophylline group, also had a longer mean duration of oxygen or CPAP use [12.56 (SD 7.67) days vs. 8.40 (SD 6.41) days; P=0.030] and duration of FiO2 taper [5.76 (SD 2.68) vs. 4.08 (SD 2.54); P=0.035]. There were no significant differences in mean time to full feeding and mean length of hospital stay. There was no significant difference in the occurrence of side effects between the two groups.
Conclusion In premature neonates with AOP, oral theophylline is slightly more effective than oral caffeine in reducing the frequency of apnea and is associated with a shorter duration of oxygen or CPAP use and duration to reach 21% FiO2.
Analysis of digital marketing and its effect on the positioning of Peruvian universities in 2023
Authors: Canaza Calsina Yilda Lisset , Torvisco Becerra Aldo Jeampiere , Angulo Bustinza Harold Delfín
Published: September 2024

Introduction/Objective: Any change and strategic advertising and/or commercial planning carried out by means of digital media is called digital marketing, which helps universities to position themselves, which is why Peruvian universities create and share relevant content on digital platforms. The objective of this study is to determine how digital marketing affects the positioning of Peruvian universities. Methodology: A quantitative approach and a deductive, non-experimental research design were used. A survey instrument was applied to 433 students studying at the Universidad Continental (located in Arequipa, Cusco, Huancayo, and Lima), and the Partial Least Squares Structural Equation Modelling (PLS-SEM) model was used, a multivariate statistical method for analysing the independent variable of digital marketing and the dependent variable of positioning. Results: The study found that the variation in units of Customer Acquisition, Customer Conversion, and Content Distribution generates a variation in positioning of 0.36, 0.24, and 0.20 units, respectively. Conclusions: Customer Acquisition is the most determining factor for positioning, followed by Conversion and, finally, Content Distribution. Additionally, it is established that Customer Acquisition primarily impacts the Service level, while Content Distribution has a greater influence on the Staff level.
Scholars and Literati at the University of Uppsala (1477–1800)
Authors: De la Croix David
Published: September 2024

This note is a summary description of the set of scholars and literati who taught at the University of Uppsala from its inception in 1477 to 1800. For more detailed information about these individuals, please visit the comprehensive database available at https://shiny-lidam.sipr.ucl.ac.be/scholars/.
Martin Musílek (ed.), Ceny – mzdy – peníze: Ekonomické myšlení ve středověkých a raně novověkých městech, Praha 2023
Authors: Boukal Jan
Published: September 2024

Book review on Martin Musílek (ed.), Ceny – mzdy – peníze: Ekonomické myšlení ve středověkých a raně novověkých městech, Argo, Praha 2023, 368 s., ISBN 978-80-257-4062-0
Raimo Pullat – Tõnis Liibek, Auf der Suche nach der eigenen Alma Mater. Ingenieure und Architekten aus Estland, die vor dem Zweiten Weltkrieg an Technischen Universitäten Europas studiert haben, Karlsruhe 2022
Authors: Svobodný Petr
Published: September 2024

Book review on Raimo Pullat – Tõnis Liibek, Auf der Suche nach der eigenen Alma Mater. Ingenieure und Architekten aus Estland, die vor dem Zweiten Weltkrieg an Technischen Universitäten Europas studiert haben, KIT Scientific Publishing, Karlsruhe 2022, 506 s., ISBN 978-3-7315-1215-8
Anthropology of Hope (Editorial)
Authors: Noble Tim
Published: September 2024

Editorial
Multidimensional Self-Regulation Battery for Reading Comprehension: Preliminary Evidence for Criterion Validity
Authors: Ferraz Adriana Satico , Aparecida Angeli dos Santos Acácia , Porto Noronha Ana Paula , S. Almeida Leandro
Published: September 2024

The purpose of this study was to investigate the validity based on relationships with other variables of the Self-Regulation for Reading Comprehension Multidimensional Battery (BAMA-RC). This study was developed quantitatively, with a cross-sectional and correlational design. Participants were 182 middle school students from Brazil. Nine BAMA-RC scales and a Cloze test were used to assess reading comprehension. The data were analyzed using statistics that evaluate relationships between variables (correlation, linear regression, chi-square test, Kruskal-Wallis and Mann-Whitney). The results identified preliminary evidence of criterion validity, confirming the hypotheses of relationships between the dimensions of self-regulation for learning and reading comprehension. These findings encourage new studies to extend the psychometric properties of the BAMA-RC.
Existence and concentration of solutions for a fractional Schrödinger–Poisson system with discontinuous nonlinearity
Authors: Mu Changyang , Yang Zhipeng , Zhang Wei
Published: September 2024

In this paper, we study the following fractional Schrödinger–Poisson system with discontinuous nonlinearity:

ε

2
s

(

−
Δ

)

s

u
+
V

(

x

)

u
+
ϕ
u
=
H

(

u
−
β

)

f

(

u

)

,

in

R

3

,

ε

2
s

(

−
Δ

)

s

ϕ
=

u

2

,

in

R

3

,

u
>
0
,

in

R

3

,

$$\begin{cases}^{2s}{\left(-{\Delta}\right)}^{s}u+V\left(x\right)u+\phi u=H\left(u-\beta \right)f\left(u\right),\quad \hfill & \text{in} {\mathbb{R}}^{3},\hfill \\ {\varepsilon }^{2s}{\left(-{\Delta}\right)}^{s}\phi ={u}^{2},\quad \hfill & \text{in} {\mathbb{R}}^{3},\hfill \\ u{ >}0,\quad \hfill & \text{in} {\mathbb{R}}^{3},\hfill \end{cases}$$

where ɛ > 0 is a small parameter,

s
∈

(

3

4

,
1

)

$s\in \left(\frac{3}{4},1\right)$

, β > 0, H is the Heaviside function, (−Δ)
s

u is the fractional Laplacian operator,

V

:

R

3

→
R

$V :{\mathbb{R}}^{3}\to \mathbb{R}$

is a continuous potential and

f

:
R
→
R

$f :\mathbb{R}\to \mathbb{R}$

is superlinear continuous nonlinearity with subcritical growth at infinity. By using nonsmooth analysis, we investigate the existence and concentration of solutions for the above problem. Moreover, we obtain some properties of these solutions, such as convergence and decay estimate.
The Unholy Grail of cancer screening: or is it just about the Benjamins?
Authors: Chatanaka Miyo K. , Yousef George M. , Diamandis Eleftherios P.
Published: September 2024

The biotechnology company Grail developed a non-invasive blood test (Galleri test) which is claimed to detect 50 types of cancer at early and potentially curable stages. The initially promising results from prospective studies, and the anticipated financial success of Grail led the sequencing giant Illumina to purchase Grail for $8 billion (2021). Following this event, Grail collaborated with the UK National Health System to further clarify the test’s capability, in a 3-year prospective trial, along with the standard of care. The UK-NHS announced that the trial will provide a clearer understanding of the efficacy of the Galleri test within the NHS framework. If the test does not perform as expected, valuable insights will still be gained to guide future research aimed at enhancing cancer screening. We previously expressed concerns about the sensitivity and specificity of the Galleri test. In this opinion paper, we revisit the hyped technology, and we provide new suggestions on the use of this test.
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology
Authors: Vogt Arend , Paulat Raik , Parthier Daniel , Just Verena , Szczepek Michal , Scheerer Patrick , Xu Qianzhao , Möglich Andreas , Schmitz Dietmar , Rost Benjamin R. , Wenger Nikolaus
Published: September 2024

The biophysical characterization and engineering of optogenetic tools and photobiological systems has been hampered by the lack of efficient methods for spectral illumination of microplates for high-throughput analysis of action spectra. Current methods to determine action spectra only allow the sequential spectral illumination of individual wells. Here we present the open-source RainbowCap-system, which combines LEDs and optical filters in a standard 96-well microplate format for simultaneous and spectrally defined illumination. The RainbowCap provides equal photon flux for each wavelength, with the output of the LEDs narrowed by optical bandpass filters. We validated the RainbowCap for photoactivatable G protein-coupled receptors (opto-GPCRs) and enzymes for the control of intracellular downstream signaling. The simultaneous, spectrally defined illumination provides minimal interruption during time-series measurements, while resolving 10 nm differences in the action spectra of optogenetic proteins under identical experimental conditions. The RainbowCap is also suitable for studying the spectral dependence of light-regulated gene expression in bacteria, which requires illumination over several hours. In summary, the RainbowCap provides high-throughput spectral illumination of microplates, while its modular, customizable design allows easy adaptation to a wide range of optogenetic and photobiological applications.
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response
Authors: Moseler Anna , Wagner Stephan , Meyer Andreas J.
Published: September 2024

Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge about the dynamics of PTMs in time and space. A PTM that gained increasing attention in the last decades is protein persulfidation, where a cysteine thiol (-SH) is covalently bound to sulfane sulfur to form a persulfide (-SSH). The precise cellular mechanisms underlying the presumed persulfide signaling in plants are, however, only beginning to emerge. In the mitochondrial matrix, strict regulation of persulfidation and H2S homeostasis is of prime importance for maintaining mitochondrial bioenergetic processes because H2S is a highly potent poison for cytochrome c oxidase. This review summarizes the current knowledge about protein persulfidation and corresponding processes in mitochondria of the model plant Arabidopsis. These processes will be compared to the respective processes in non-plant models to underpin similarities or highlight apparent differences. We provide an overview of mitochondrial pathways that contribute to H2S and protein persulfide generation and mechanisms for H2S fixation and de-persulfidation. Based on current proteomic data, we compile a plant mitochondrial persulfidome and discuss how persulfidation may regulate protein function.
Optimization of Cost-Based Hybrid Flowshop Scheduling Using Teaching-Learning-Based Optimization Algorithm
Authors: Ullah W. , Mu'tasim M.A.N. , Rashid M.F.F.
Published: September 2024

A cost-based hybrid flowshop scheduling (CHFS) combines flow shop and job shop elements, with cost considerations as a key indicator. CHFS is a complex combinatorial optimization challenge encountered in real-world manufacturing and production environments. This paper investigates the optimization of a CHFS problem using the Teaching Learning-Based Optimization (TLBO) algorithm. Effective CHFS is crucial for achieving production balance, reducing costs, and improving customer satisfaction. The authors formulate the CHFS scheduling problem and propose applying the TLBO algorithm to minimize total costs, including labor, energy, maintenance, and delay expenses. The performance of the TLBO technique is evaluated through computational experiments on various CHFS problem instances. The results demonstrate the effectiveness of the TLBO algorithm, which achieved the best results in 42% of the test cases, surpassing other algorithms like the Grey Wolf Optimizer and Particle Swarm Optimization. Additionally, the TLBO algorithm had the highest average performance ranking across the comparative algorithms. The study highlights the potential of the TLBO algorithm as an efficient optimization tool for complex manufacturing scheduling problems.
Reconstructing Magnetic Hysteresis Behavior with Flux Model and Identifying Parameters for Dual-Coil MR Actuator
Authors: Tang Lei , Bankosz Wojciech , Goldasz Janusz
Published: September 2024

Magnetorheological (MR) actuators represent an important class of semi-active devices that have received extensive investigation and deployment in the field of vibration reduction systems. Their notable features include a significant reduction in energy consumption, along with an impressive tunable range of continuously controllable damping forces. The force output of these devices is a complex function that involves two hysteretic mechanisms: magnetic and mechanical (i.e. hydraulic). While the total hysteresis mechanism of these devices has been the subject of considerable study, comparatively little attention has been paid to their magnetic hysteretic behavior. In this study, the authors examine the behavior of the dual coil MR actuator’s control circuit and attempt to extract the magnetic flux information from the laboratory measurements of electrical signals applied to it. The study is further enhanced by the incorporation of the Bouc-Wen (B-W) hysteretic unit, which serves to replicate the flux-current (or magnetic) hysteretic relationship. The B-W model's parameters are identified through the use of a hybrid algorithm, namely the particle swarm optimization and fmincon hybrid optimizing strategy. It incorporates the advantages of both algorithms, resulting in an average improvement of 0.38% in standard deviation compared to fmincon, across 1A to 5A, when comparing the experimental and simulation data. This strategy is employed to fit the model predictions to the flux data, derived from the reconstructed flux and current in time histories. The findings of the study demonstrate that the B-W model is an effective tool for predicting the variation in magnetic flux in response to an exciting current. The results can be implemented for prototyping or validating a model-based controller for MR actuator systems.
Experimental and Numerical Modelling of Ballistic Impact on Fiber Metal Laminates Based on Aramid Fiber Reinforced Epoxy
Authors: Fadly Muhammad Syaiful , Purnowidodo Anindito , Setyarini Putu Hadi , Bakri B , Chandrabakty Sri
Published: September 2024

This paper investigates the ballistic impact behavior of fiber metal laminates (FML) composed of aramid fiber-reinforced epoxy with a central layer of aluminum alloy Al5083. The research examines the ballistic performance influenced by factors such as hole shape and depth in the laminate and integrates both macro and microstructural analyses of FMLs. The FML variations studied included a perforated first layer with hole diameters of 3 mm and 5 mm, through which bullets penetrated. Ballistic tests were conducted from a firing distance of 5 meters using 9-mm cartridges loaded with full metal jacket bullets approximately 25 mm wide, fired at an angle perpendicular to the target surface. The experimental and simulation ballistic impact tests closely matched, with a 95.63% agreement and an error margin of about 4.37%. The FML resisted bullet impact by allowing perforation through three layers (the aluminum plate and the first and second aramid/epoxy plies) while forming a bulge due to longitudinal deformation in the final layer (the back plate). The experimental and simulation results showed similar trends, with a 5 mm diameter hole leading to a deeper bulge on the backside. Bullet penetration at the center, following a square pattern, resulted in the smallest bulge formation and a reduction in both initial and final bullet velocities. The fracture morphology indicates a ductile fracture, characterized by dominant dimple formations across the surface. The dimples in the FMLs are coarser than those in monolithic aluminum plates due to the reduced bullet velocity as it penetrates each layer of the target FMLs, significantly decreasing the remaining bullet velocity. In contrast, monolithic aluminum plates exhibit a minimal velocity decrease, resulting in smoother dimple fractures.
Consistency of the Non-Invasive Monitoring Preemie Car Seat (PreeCASE) Device in Assessing Heart Rate, SpO2 Level, and Body Temperature of the Infants
Authors: Md Zin Muhammad Afiq Firdaus , Mohd Adib Mohd Azrul Hisham
Published: September 2024

Advancements in technology have made pulse oximeter devices the preferred choice for parents monitoring their baby's health. However, existing devices present challenges for infants, especially preemies, who need continuous monitoring after being discharged from the hospital. Using conventional baby car seats with wired connections and unstable external vital sign monitors may lead to inaccurate data readings. To resolve this issue, the non-invasive monitoring preemie car seat (PreeCASE) device is well-developed. In this study, we focus on investigating the consistency of the PreeCASE device in assessing the heart rate, SpO2 level, and body temperature of healthy infants. For the methods, ten healthy infants are selected to use the PreeCASE device, and the data is collected and analyzed using standard procedure. The PreeCASE device provides consistent data readings for the three main physiological parameters, heart rate SpO2 level, and body temperature that are displayed on an LCD screen based on the user’s respective levels. The PreeCASE device is precisely designed to facilitate easy and rapid monitoring of infants, especially preemie infants. This innovative device holds significant potential to improve and support pediatricians in effectively caring for infants in Malaysia.
Glucagon-like peptide-1 analog, liraglutide, regulates Sertoli cell energy metabolism
Authors: Dasso Marina Ercilia , Centola Cecilia Lucia , Galardo María Noel , Meroni Silvina Beatriz , Riera María Fernanda
Published: September 2024

Liraglutide, an analog of the incretin hormone glucagon-like peptide 1 (GLP-1), is widely used for obesity and type 2 diabetes treatment. However, there is scarce information about its effects on testicular function. Within the testis, Sertoli cells (SCs) provide nutritional support for germ cells; they metabolize glucose to lactate, which is delivered to germ cells to be used as a preferred energy substrate. Besides, SCs use fatty acids (FAs) as an energy source and store them as triacylglycerols (TAGs) within lipid droplets (LDs), which serve as an important energy reserve. In the present study, 20-day-old rat SC cultures were used to assess whether liraglutide affects their metabolic functions related to nutritional support and lipid storage. The results show that liraglutide does not modify glucose consumption or lactate production. However, it increases TAG levels and LD content. These effects are accompanied by an increase in the mRNA levels of the fatty acid transporter FAT/CD36, glycerol-3-phosphate-acyltransferase 3, and perilipins 1 and 4. The participation of the cAMP/PKA signaling pathway was explored. We observed that H89 (a PKA inhibitor) decreases the LD upregulation elicited by liraglutide, and that dibutyryl cAMP increases LD content and the expression of related genes. In summary, liraglutide promotes lipid storage in SCs through the regulation of key regulatory genes involved in FA transport, TAG synthesis, and LD formation. Considering the importance of lipid storage in SC energetic homeostasis maintenance, we postulate that liraglutide might improve the overall energetic status of the seminiferous tubule.
THE POTENTIAL OF SMART TECHNOLOGIES TO REDUCE YOUTH MIGRATION IN THE RUSSIAN ARCTIC REGIONS
Authors: ДЕТТЕР Г.Ф. , ЛЁВКИН В.Е. , АНДРИАНОВ К.В. , ЛЁВКИНА А.О.
Published: September 2024

Основные риски устойчивого развития Российской Арктики определяют социально-демографические факторы: низкая численность населения, миграционный отток, отставание качества жизни от общероссийского уровня, несоответствие имеющихся возможностей в области образования потребностям экономики и социальной сферы арктических регионов. Молодежь является основой для роста человеческого и интеллектуального потенциала Арктики и в то же время обладает повышенной мобильностью. Это обусловливает высокую актуальность поиска эффективных решений по сокращению миграционного оттока молодежи, в том числе за счет быстро развивающихся возможностей цифровых технологий. В статье изложены результаты пилотажного исследования, тестирующего гипотезу о возможности применения цифровых технологий для повышения качества жизни молодежи арктических регионов и сокращения ее миграционного оттока. Анализ выявил, что применение технологий онлайн-образования в целях повышения доступности и качества образования может значительно повлиять на выбор молодежью арктических территорий в качестве места для жизни, работы и развития.

The sustainable development of the Russian Arctic faces primarily socio-demographic risks: low population, migration outflow, subpar quality of life compared to the national average, and a mismatch between available educational opportunities and the needs of the Arctic economy and social sphere. Given that young peopleplay a crucial role in this area's human and intellectual potential, their increased mobility in Arctic regions highlights the urgent need to find effective solutions to reduce youth migration. This can be achieved through the utilization of rapidly advancing digital technologies and smart solutions. This article presents the findings of a pilot study that aimed to test the hypothesis regarding the possible benefits of digital technologies in improving the quality of life for Arctic youth and mitigating their migration outflow. The results revealed significant potential for digital technologies to address the issue of youth migration outflow. In particular, the use of distance technologies to enhance the accessibility and quality of education can greatly influence young people's decision to choose Arctic territories as their place of residence, work, and personal growth.
Pioniers of Microsurgery: the Touch of History
Authors: Špokevičius Saulius
Published: September 2024

Every hand and microsurgeon worldwide is more or less familiar with the names of those who are mentioned in this article: Harry Buncke, Harold E. Kleinert, Robert Acland, Hanno Millesi and Algimantas Otonas Narakas. Who ever new or were familliar with them experienced feeling as it was “the royal touch” for those who had a scropulosis in the middle ages: the touch was healing and left the unforgettable memories – they were toutched by a queen or a king. Every contact with the giants of microsurgery left noteworthy memories of their lavish lessons and cordial advises. The author had a very close professional contacts with all of them and is eager to share some of the highlights spent with them in operating rooms, writing articles and discussing subjects during the scietific meatings.
Effects of starter cultures and processing unit operations on the physicochemical compositions of odourless ‘Fufu’
Authors: CY Babatuyi , BE Boboye , TN Fagbemi
Published: September 2024

'Fufu' is a starchy staple food usually made from fermented cassava mash, characterized by undesirable odour-producing compounds due to microbial enzymatic activities with inherent objectionable odour during fermentation. This reduces its acceptability to the consumer. The cassava roots biomass have different microorganisms (i.e. bacteria and fungi). Each class of the microorganism (s) identified was separated. Six out of eight 'fufu' (8) samples were fermented with identified microorganisms as starter cultures and coded OBP (Only Bacteria); YBP (Yeasts and Bacteria) OYP (Only Yeasts); MBP (Moulds and Bacteria); YMP (Yeasts and Moulds) and OMP (Only Moulds). Samples WIG (Without Inoculum, but Grated) and WIS (Without Inoculum, but Soaked) were produced without inoculum. The market sample (MTE) served as a control for sensory. The protein content of sample MBP had the highest (3.68 g/100 g) value. The cyanide level of sample WIG and some 'fufu' fermented with starter cultures were drastically reduced. The aroma of the 'fufu' samples fermented with starter cultures was much better than sample MTE.
Parental interference in custody variation proceedings: a forensic psychology perspective
Authors: Mateo-Fernández Pedro V. , la Osa-Subtil Iria de
Published: September 2024

Parental interference in judicial proceedings for variation of custody arrangements is a phenomenon that profoundly impacts family dynamics and the well-being of children. This article addresses this issue from the perspective of forensic psychological assessment, highlighting the critical importance of a thorough and rigorous analysis in these contexts. Custody variation, whether physical or legal, often generates tension and conflict between parents, which can lead to parental interference behaviors. These interferences can manifest themselves in a variety of ways, including emotional manipulation of children, denigration of the other parent, and obstruction of parenting time. The relevance of this article lies in the need to understand how these interferences affect both the children and the adults involved, and the importance of having accurate and objective psychological assessments to inform court decision-making. The work of the forensic psychologist is essential in these processes, providing an unbiased assessment based on standardized techniques and tools to identify harmful family dynamics and their impact on the psychological well-being of children. Throughout this article, the importance of early intervention and the implementation of effective strategies to mitigate parental interference is highlighted. In addition, recommendations for courts and other legal professionals on how to appropriately integrate findings from psychological evaluations into judicial decision making are highlighted. Ultimately, this approach seeks to promote the well-being of children and ensure that custody decisions are based on the best interests of the child, informed by rigorous and detailed forensic psychological evaluations.
Ukraine on Fire Cinema Novel by Oleksandr Dovzhenko: Saving Gesture of the Artist
Authors: Trymbach Serhiі
Published: September 2024

The years of German-Soviet war (1941–1945) have become a period of special trials for the outstanding film director Oleksandr Dovzhenko. All hopes for the revival of the Ukrainian nation and its culture have turned out to be an illusion. The victory of the Soviet Union in the war has led to the collapse of the remnants of political and cultural autonomy in Ukraine, complete control of the imperial center over the processes of social and cultural life. Dovzhenko writes the film story Ukraine on Fire, which demonstrates the considerable resources of resistance of Ukrainians to totalitarian systems – both Soviet and German. In addition, Dovzhenko as an author reveals the intention of a national prophet who believes in his magical ability to save his people. The author has special sympathy for Ukrainian girls and women. They are killed, raped, humiliated. However, they remain special bearers of the nation mentality, its cultural and artistic memory. Its beauty! Therefore, the images of women are permeated with folklore and literary motifs, those voice out and materialize the world of Ukrainians who oppose the war. The story has drawn a lot of criticism from the dictator Stalin, criticism made public during a special meeting in the Kremlin. The accusations have been reduced to alleged manifestations of nationalism, revision of the very foundations of the Bolshevik empire. The work has been banned from publication and production in the cinema. Today, in the context of the new stage of war of the Russian Empire against Ukraine, the work in which the artist at the time of the disaster, is on the edge of the abyss and the non-existence of the people, comes to its defense, acquires special relevance and worldview expressiveness. Ukraine on Fire is distinguished by the special lyrical nature of the text, it is permeated with folk singing, folklore images and even rhythm. An amazing consonance with the folk melos, a powerful lyric-epic coverage of folk life. The completion of work on the film story has coincided with the beginning of the stay of Dovzhenko’s mother, Odarka Yermolaivna, in Moscow, in Dovzhenko’s apartment (after the end of the German occupation of Kyiv). The artist has recorded a number of folk songs from her, those have a significant impact on the work on the following scenarios – Chronicle of Flaming Years, Enchanted Desna, Poem of the Sea.
Arab Spring: Perubahan Otoritas, Stabilitas Politik dan Perkembangan Ekonomi di Timur Tengah
Authors: Effendi Orien
Published: September 2024

This article examines the failure of the Arab Spring and the extent to which post-Arab Spring changes in authority have an impact on political and economic stability in the Middle East region such as Tunisia, Libya, Syria, Egypt and Yemen. The data in this research was collected from primary and secondary materials as well as field facts. Using a sociological-political and juridical-empirical approach, this article concludes that there are a number of factors in the failure of the Arab Spring, namely the unpreparedness of the Arab people in implementing a democratic system considering that they have used a monarchical system for centuries, there is domestic and regional polarization between countries in the Arab region. due to the pros and cons of the concept of democratization, and also the existence of foreign intervention. This article also finds evidence that changes in authority after the Arab Spring have actually had an impact on political and economic instability due to strengthening tribalism and competition between political elites in fighting for power after the fall of the previous regime. Apart from that, this research found another fact that the differences in economic conditions between countries in the Middle East region are not completely influenced by the chosen state system, although the democratization transition has also influenced political stability and then had an impact on the country's economic stability.
Factors associated with preventable infant mortality in 2020: a Brazilian population-based study
Authors: Sousa Mikaelly Rayanne Moraes , Parada Cristina Maria Garcia de Lima , Nunes Hélio Rubens de Carvalho
Published: September 2024

ABSTRACT Objectives: to identify factors associated with preventable infant deaths, classified as neonatal and post-neonatal. Methods: this is an epidemiological and population-based study relating to 2020. Data from the Mortality Information System (MIS) and the preventability classification proposed in the Brazilian Health System List of Causes of Deaths Preventable by Interventions were used. Results: prematurity, living in the North and Northeast regions and the occurrence of the event at home were associated with preventable neonatal deaths. To the avoidable post-neonatal component, death outside the hospital, low maternal education and children of brown or yellow color/race were associated. Conclusions: the main risk factor associated with preventable deaths was prematurity, in the case of neonatal death. Low maternal education and occurrence outside the hospital were associated with post-neonatal deaths.
Experiência de pesquisadores na coleta de dados com famílias de vítimas de feminicídio
Authors: Reis Igor de Oliveira , Scherer Edson Arthur , Scherer Zeyne Alves Pires
Published: September 2024

RESUMO Objetivos: descrever a experiência de pesquisadores na coleta de dados com famílias de vítimas de feminicídio. Métodos: estudo descritivo, qualitativo, tipo relato de experiência, realizado em Manaus, Amazonas, Brasil. Foi realizada uma consulta documental, capacitação dos pesquisadores, agendamento e realização de entrevistas, utilizando um diário de campo para o registro das percepções e vivências dos pesquisadores. Resultados: a descrição e as fotografias da cena do crime afligiram e impactaram os pesquisadores. As lembranças da vítima (roupas, objetos e fotos de infância), mostradas pela família, os comoveram. Identificar essas vivências facilitou ouvir a história relatada pelos familiares. Manter uma atitude de não julgamento, não negação da perda, acolhimento do sofrimento e demonstração de disponibilidade para ajudar foram fundamentais. Considerações Finais: a experiência perpassou aspectos teóricos-metodológicos planejados e executados na coleta de dados, proporcionando o desenvolvimento de habilidades e a sensibilização com os casos. Além de conhecimento e preparo, espera-se atitude ética e capacidade empática dos pesquisadores.
Sociocognitive factors determining compliance with standard precautions by nursing professionals during the COVID-19 pandemic
Authors: Santos Andressa Silva Torres dos , Silva Ana Cristina de Oliveira e , Pereira-Ávila Fernanda Maria Vieira , Coêlho Hemílio Fernandes Campos , Sousa Laelson Rochelle Milanês , Reis Renata Karina , Gir Elucir
Published: September 2024

ABSTRACT Objectives: to assess the socio-cognitive factors determining adherence to standard precautions by nursing professionals in care practice during the COVID-19 pandemic in Brazil. Methods: an analytical cross-sectional study, carried out with 9,039 nursing professionals in Brazil, using an electronic form containing participant sociodemographic, training and work variables, and the Brazilian version of the Standard Precautions Questionnaire. Descriptive and inferential statistics were used using the statistical software R. Results: participants recognize standard precautions as effective measures to reduce infections and report intention to perform them. Training regarding standard precautions was evidenced as a facilitator of adherence (4.72; SD: 0.73), and problems related to materials (3.78; SD: 1.45) were a hindrance. Conclusions: among the determining factors, facilitating organization presented the highest score, followed by intention to perform. Facilitating and hindering factor identification makes it possible to develop intervention strategies to strengthen patient safety and reduce occupational risks among professionals.
Construção e validação de lista de checagem para manejo do cateter totalmente implantado em crianças
Authors: Souza Giselle Vieira de , Souza Isabella Pavarine de , Silva Maria Paula Custodio , Toffano Silmara Elaine Malaguti , Contim Divanice
Published: September 2024

RESUMO Objetivos: construir e validar o conteúdo de uma lista de checagem para manejo do cateter totalmente implantado em crianças e adolescentes hospitalizados. Métodos: Pesquisa metodológica realizada no período de outubro de 2021 a dezembro de 2022, em duas etapas: elaboração do instrumento com diretrizes para o cuidado e validação de conteúdo da lista de checagem. O instrumento, contendo 23 itens apresentados em formato Likert, foi avaliado online por especialistas em duas rodadas. Aplicou-se o Índice de Validade de Conteúdo, considerando válidos os índices acima de 0,8. Resultados: a lista final contemplou quatro domínios e 22 itens de checagem, sendo validada com Índice de Validade de 0,98. A avaliação geral do instrumento apresentou uma nota global de 9,9. Conclusões: a validação e aplicação de instrumentos que padronizam os procedimentos, além de respaldar o profissional, promovem autonomia e qualidade da assistência à criança e ao adolescente em uso deste dispositivo.
Brazilian nursing specific situation, middle and micro-range theories: a bibliometric study
Authors: Cardoso Rosane Barreto , Brandão Marcos Antônio Gomes , Cavalcante Jéssica Cristina Sobrinho da Silva , Lopes Rafael Oliveira Pitta , Zaccaro Kênia Rocha Leite , Primo Cândida Caniçali
Published: September 2024

ABSTRACT Objectives: to map the nursing theories developed in stricto sensu graduate programs in nursing in Brazil. Methods: a bibliometric study, carried out on the Coordination for the Improvement of Higher Education Personnel Theses and Dissertations Portal in October 2023. The controlled descriptors “Nursing Theory” and “Nursing Models” and the uncontrolled descriptors “Theories” and “Middle-Range Theory” were used. Selected studies were cataloged for analysis, which was conducted by the study authors, who have a doctoral degree and expertise in research on nursing theories. Results: thirty-nine nursing theories were mapped, with a predominance of middle-range theories (79.5%), focusing on nursing diagnostic concepts and use of the theoretical-methodology strategy of theoretical-causal validity. Conclusions: the study identified nursing theories developed in Brazil, recognizing trends, development strategies, theorized objects of disciplinary interest and investments necessary for practical application in Brazilian contexts.