bluuebunny/crossref_metadata_2025 huggingface dataset:
Aplicación del Derecho comunitario y potestad sancionadora en el contexto de la Unión Europea
Authors: Molina del Pozo Carlos Francisco
Published: October 2023

El presente artículo tiene como objetivo el conocimiento de la regulación y posterior ejecución de las normas administrativas sancionadoras, tanto de los Estados miembros, como de algunas instituciones de la Unión Europea, tales como la Comisión, el Banco Central Europeo, el Consejo y el Tribunal de Justicia de la Unión Europea.

Asimismo, hace una breve síntesis de la aplicación del Derecho comunitario en los Estados miembros más significativos (España, Francia, Alemania, Reino Unido), con el fin de detallar de manera pormenorizada las peculiaridades existentes en la aplicación del mencionado ordenamiento jurídico en cada Estado.

Además, hace un recorrido por la situación actual del Derecho administrativo sancionador en el ámbito de la Unión, aclarando la cuestión de si la Unión Europea dispone o puede disponer de competencias sancionadoras en el ámbito administrativo para llevar a cabo con eficacia el proceso de integración en el cual estamos inmersos, y explicando los principios por los que se rige o puede regirse el Derecho administrativo sancionador europeo.

Destaca el papel fundamental de las competencias implícitas en el desarrollo del Derecho sancionador europeo, mencionando su eventual peligrosidad al poder suponer una violación del principio de legalidad y ofreciendo algunas posibles soluciones. Asimismo, pone de relieve la exteriorización del poder de control mediante la imposición de sanciones, llevada a cabo por la Comisión, con la estricta finalidad de hacer cumplir los actos propios del Derecho comunitario.
ENZENSBERGER, Hans M. (2012). El gentil monstruo de Bruselas o Europa bajo tutela. Barcelona: Anagrama, Colección Argumentos
Authors: De la Peña Rodríguez Luis
Published: October 2023

Recensión de la obra: ENZENSBERGER, Hans M. (2012). El gentil monstruo de Bruselas o Europa bajo tutela. Barcelona: Anagrama, Colección Argumentos.
Marco normativo en materia electoral con una alusión al régimen de la Comunidad de Madrid
Authors: González de Zárate Lorente Roberto
Published: October 2023

Reflexión sobre el marco normativo en materia electoral con una alusión al régimen de la Comunidad de Madrid.
El sistema de Tribunales Administrativos de recursos contractuales
Authors: Santamaría Pastor Juan Alfonso
Published: October 2023

El trabajo lleva a cabo una descripción crítica del sistema de tribunales administrativos creados para la resolución de recursos en materia de contratos públicos, en transposición de la Directiva 89/665/CEE del Consejo, de 21 de diciembre de 1989. Analiza con detalle los requisitos impuestos por la Directiva y la forma en que han sido aplicados por el legislador español y por las comunidades autónomas que han creado tales tribunales. En particular, examina las razones de la opción por un sistema de tribunales no judiciales, los inconvenientes y problemas derivados de la coexistencia de diversos tribunales, el estatuto de sus miembros y las cuestiones de estructura y funciones de los mismos.
Las nuevas leyes de Régimen Jurídico del Sector Público y del Procedimiento Administrativo Común: entre la cosmética y el enredo
Authors: Fernández Farreres Germán
Published: October 2023

En el presente estudio se procede a una valoración general de la finalidad, significado y alcance de las Leyes de Procedimiento Administrativo Común y de Régimen Jurídico del Sector Público, de 1 de octubre de 2015. Dicha valoración se sustenta en una exposición y comentario sucinto de las principales novedades y cambios que incorporan las mencionadas Leyes para la reforma administrativa.
La participación ciudadana, transparencia y técnica normativa en las Leyes 39 y 40 de 2015. Los principios de buena regulación
Authors: Alonso Timón Antonio Jesús
Published: October 2023

La participación ciudadana se articula como una herramienta eficaz para conseguir uno de los objetivos que el Derecho público tiene encomendado en el siglo XXI, como es el progresivo acercamiento entre Estado y Sociedad que ya en el siglo XX se había iniciado. La participación ciudadana otorga una mayor transparencia a la gestión pública y mejora la técnica normativa por el mayor conocimiento de las normas que los potencialmente destinatarios de la misma tienen sobre ella y por la consecuente reducción de la litigiosidad que ello provoca.
La potestad legislativa gubernamental: calidad de las normas y evaluación ex-ante
Authors: Álvarez Vélez M.ª Isabel
Published: October 2023

La evaluación de normas (o de la política legislativa) y de sus consecuencias (sea “ex-ante” o “ex-post”) se está convirtiendo en un ámbito de actividad jurídica cada vez más conocido y reconocido, vinculándolo a la calidad. Evidentemente, existe una relación directa entre evaluación legislativa ex-ante y ex-post: la primera permite fijar los términos a evaluar en la segunda (el cumplimiento, por ejemplo, de las previsiones recogidas en la memoria de análisis de impacto normativo) y la segunda, permite mejorar los sistemas de evaluación del impacto prospectivo. En el presente trabajo trataremos de referirnos a la calidad formal y material de los proyectos de Ley del Gobierno, ambos elementos de evaluación ex-ante. Finalizaremos nuestro estudio reflexionando acerca de los mecanismos de control que existen en nuestro sistema tanto de la calidad como de la evaluación ex-ante.
Applying the Principles of Total Quality Management in Kindergarten Institutions
Authors: Elkamaly Reham
Published: October 2023

Education at the kindergarten level is currently witnessing an increasing demand and a great diversity of its types, unprecedented, which requires educational systems to respond to this demand by providing more opportunities for these systems to change, develop, and improve the educational process in its various aspects. Hence, the organizational structure of any educational institution is the driving axis of the administrative process, and since the work cannot be carried out except after planning it, and with a solid base for its organization, this organization is concerned with distributing the work among the employees, each according to his specialization and experience; Therefore, comprehensive quality management in education means planning, directing, coordinating and following up on the components of the education system, including the material and human elements, in order to achieve efficiency and effectiveness of this human industry, which represents the outputs of the skilled workforce from top to bottom, as the skills of the workforce tend to become the main competitive weapon. In the twenty-first century.
The Impact of Social Media on Individuals’ Participation in Political Events
Authors: El-sawy Amer , Ali Abd Elhamid
Published: October 2023

Since the beginning of 2011, Egypt, like many other Arab countries, has witnessed a wave of protests, sit-ins, and marches demanding reform changes in the political, economic, and social fields. Social media has allowed the organizers of the events of this mass movement to participate and interact with the events, at the level of motivation and mobilization of general opinion. This study aimed to identify the role of social media in motivating citizens to participate in mass movement activities, using the media survey method, both descriptive and analytical, on a sample of (296) individuals from trade unionists in the city of Zagazig. One of the most prominent findings of this study was that (56.6%) of trade unionists participate (always, sometimes, and rarely) in the mass movement demanding reform and change in Egypt, through social media. The results showed that there is no statistically significant relationship between the demographic characteristics of trade unionists and participation in the mass movement via social media.
The Effect of Education and Religion in Early Childhood on Social Coexistence and Tolerance: A Case Study of Fifth and Sixth Grade Students in Damascus Governorate
Authors: Awad Cecile
Published: October 2023

The study aimed to reveal the effect of education and religion in early childhood on coexistence and societal tolerance as estimated by fifth and sixth grade students in Damascus governorate schools, and to measure the differences between the average scores of the research sample's responses to the societal tolerance scale according to the variables of gender and grade; The current research adopted the descriptive analytical approach, applied the measure of societal tolerance, and the research sample included (294) boys and girls. Among the most important results of the research: The level of influence of education and religion in early childhood on coexistence and societal tolerance according to the estimation of fifth and sixth grade students in Damascus governorate schools was average with a degree of (3.30). The grade variable is in favor of children in the sixth grade.
Urgensi Sanad dalam Meningkatkan Profesionalitas Guru Pendidikan Agama Islam
Authors: Muhammad Hamid  , Syamsul Bakri
Published: October 2023

As technology develops, Islamic Religious Education teachers are challenged to further develop their intellectual abilities so they don't lose their role to digital technology. One of the best and most appropriate methods for Islamic Religious Education teachers to increase knowledge is to study with teachers who are at a higher level or more experienced than them or are known as a sanad ‘ilm in Islam. The purpose of this research is to explain its importance a sanad ‘ilm as one of the aspects that a teacher must have in order to become a professional teacher in his field.
This study uses a literature approach (Library Research) and descriptive analysis in writing so that the results of this study are in the form of an explanation of the collected library data.
The results of this study explain that the method takes a sanad ‘ilm with the aim of increasing aspects of a teacher's knowledge is very important and has the basis of the arguments of the Qur’an and Hadith. It doesn't end there, even with a sanad ‘ilm the scientific knowledge of a teacher will at least get three benefits, namely can improve intellectual aspects, scientific originality, objective in viewing, and principled in science.
Keywords: Urgency of Sanad; Intellectual Ability; PAI Teachers Professionalism.
Strategi dan Media Pembelajaran Sejarah Kebudayaan Islam di Madrasah Ibtidaiyah
Authors: Atik Fauziah  , Lailatul Maqhfiroh  , Alifa Retna Handriyansari
Published: October 2023

The subject of Islamic Cultural History is one of the subject that is somewhat less interesting for student feel sleepy. This is heavily influenced by factors in the learning process that are less fun and lack the creativity of a theacher in the teaching and learning process when interacting with student in the classroom.
SKI material whose characteristics are past Islamic history material is conveyed or oven told casually with a lecturing or storytelling learning model. This kind of learning model makes students just sit and listen to what is conveyed by the teacher so that creative thinking and student material capture are not optimal.
To overcome this problem a theacher must have many strategies in conveying a lessonass well as involving the media in its delivery. Therefore, in this article we will discuss strategies and media that can be used in learning the history of Islamic culture. With the aim of providing insight for teachers and providing insight for teachers in delivering good, effective and innovative learning materials.
Keywords: History of Islamic Culture; Strategy; Media.
A STUDY ON FACTORS INFLUENCING THE CONSUMER BUYING BEHAVIOR WITH REFERENCE TO ORGANIZED APPAREL RETAIL OUTLETS
Authors: V. Gunder Chandrakala , C. U. Sowmya , H. G. Nagesha
Published: October 2023

The Indian Retail sector has come off age and has gone through major transformation over the last decade with a noticeable shift towards organized retailing. Modern retail formats, such as hypermarkets, superstores, supermarkets, discount and convenience stores are widely present in the developed world, whereas such forms of retail outlets have only just begun to spread to developing countries in recent years in Bangalore. Organized retail provides consumers with a wider choice of products, lower prices, and a pleasant shopping environment. Store atmospherics plays an important role in choice of the stores. The objective of this study is to identify the store related factors that have an influence on the consumers’ decision process. Structured questionnaires were administered for a sample size of 400 customers who visited the shopping mall. There are several dimensions in a retail store.Hence,PL-SEM model has been used and three factors have been identified from the factor loadings analysis. The three factors under different parameters are-External Cues, Atmospherics and Merchandise.
Hvad vi taler om, når vi taler om kreativitet
Authors: Tanggaard Lene , Brinkmann Svend
Published: October 2023

Kreativitet og innovation er nogle af de i øje- blikket mest fejrede begreber. Csikszentmihalyi skriver i 2006, at kreativitet ikke længere er en luksus for de få, men en nødvendighed for alle. Og Sawyer (2012) hævder i sin nye bog med titlen Explaining Creativity, at kreativitet og evnen til at være opfindsom og bruge sin fantasi er de ypperligste menneskelige kompe- tencer overhovedet. Man kunne dog med lige så stor ret hævde det modsatte: At menneskets fremmeste evne er evnen til at standardisere og stabilisere en verden, der ellers konstant er i forandring. Mange kreativitetsforskere glemmer, at opfindsomhed og innovation kun giver mening på en baggrund af rutiner og stabilitet, som det ofte kræver en stor indsats at opretholde. På den baggrund vil vi gøre følgende to ting i denne artikel:

1) Argumentere for, at kreativitet vokser ud af rutine- og vanemæssige praksisser – og at disse rutiner og vaner i forskellige kul- turelle sammenhænge er under pres

2) Argumentere for, at de rutine- og vanemæs- sige praksisser med fordel kan undersøges fra et hverdagsforskningsperspektiv.
Analyse des motivations associées à la pratique du chemsex selon l’orientation sexuelle
Authors: This Jeanne , Lafortune David , Flores-Aranda Jorge
Published: October 2023

Problématique et objectif : La consommation des substances en contexte sexuel – aussi connu sous le nom de chemsex – a surtout été documentée chez les hommes gais, bisexuels ou ayant des relations sexuelles avec d’autres hommes (gbHARSAH), avec de rares études incluant des hommes hétérosexuels. Par ailleurs, les motivations associées au chemsex demeurent sous-documentées, nonobstant l’orientation sexuelle primaire rapportée. Cette étude qualitative exploratoire visait à décrire les motivations associées à la pratique du chemsex chez les hommes et à explorer les possibles différences selon leur orientation sexuelle primaire.

Méthodologie : Onze hommes cisgenre (>18ans) rapportant avoir consommé en contexte sexuel au moins une des substances associées au chemsex (méthamphétamine, cocaïne, kétamine, MDMA ou GHB) dans la dernière année ont participé à un entretien semi-directif. Une analyse thématique a été réalisée en utilisant la théorie de l’autodétermination (Ryan et Deci, 2000) pour organiser et conceptualiser les thèmes émergents relatifs aux motivations intrinsèques et extrinsèques associées à la pratique du chemsex.

Résultats : Les motivations extrinsèques rapportées faisaient référence à (1) l’influence de normes sociosexuelles intériorisées ou (2) des partenaires sexuels dans l’initiation ou le maintien de la pratique du chemsex. Les motivations intrinsèques incluaient le désir (1) d’améliorer la performance sexuelle et des sensations physiques ; (2) de réduire les inhibitions lors d’interactions sexo-relationnelles ; (3) de favoriser la connexion émotionnelle au.x partenaire.s ; (4) d’atténuer l’impact d’émotions ou d’événement douloureux ou alors (5) de combler un besoin lié à une dépendance aux substances.

Discussion : Nos résultats relèvent les facettes multiples du chemsex en matière de facteurs individuels, relationnels ou culturels influençant sa pratique, de même que le caractère heuristique du modèle de l’autodétermination pour distinguer les profils d’utilisateurs relativement à leurs motivations et leur orientation sexuelle primaire.
L’évaluation des limitations à l’emploi en contexte de dépendances : une question d’équité
Authors: Giguère Nadia , Handfield Stéphane , Barbeau David , Beaulieu Marie-Dominique
Published: October 2023

(Ré)intégrer le marché du travail et se maintenir en emploi représente un grand défi pour les personnes traitées pour un trouble lié à l’usage des opioïdes. Ces personnes se tournent donc souvent vers les programmes d’aide financière, qui peuvent être majorés de 57 % si un rapport médical documentant les limitations fonctionnelles donne lieu à une reconnaissance de contraintes sévères à l’emploi. L’évaluation de ces limitations est cependant un acte médical complexe, particulièrement pour des patients ayant des troubles liés à l’usage de drogue ou d’alcool.

L’étude de cas réalisée dans un centre de traitement de la dépendance aux opioïdes visait à documenter : 1) les critères utilisés par les professionnels impliqués dans l’évaluation ; et 2) le vécu des personnes requérantes. Les données recueillies proviennent d’entretiens menés auprès de sept professionnels et 18 usagers et de deux groupes de discussion formés d’une vingtaine de professionnels.

L’analyse thématique montre que cinq types de critères sont utilisés par les professionnels : 1) les facteurs médicaux et psychosociaux ; 2) l’employabilité de la personne ; 3) sa crédibilité ; 4) les impacts potentiels de la reconnaissance des contraintes à l’emploi et de l’accès aux prestations majorées ; 5) leurs valeurs individuelles. Également cinq thèmes principaux émergent des entrevues avec les usagers : 1) l’anxiété liée au processus médico-administratif ; 2) la difficulté à accepter le refus de reconnaissance des contraintes ; 3) les impacts anticipés ou ressentis de l’accès aux prestations majorées, qui tendent à montrer le fort potentiel des interventions sur le revenu ; 4) la grande valeur accordée au travail et le soulagement de voir reconnaître ses difficultés en emploi ; 5) la variabilité des réactions des usagers à l’égard de l’officialisation d’un diagnostic.

Des pistes de réflexion sont proposées pour l’évaluation des limitations à l’emploi dans une perspective de promotion de la santé. Celles-ci incluent une approche interdisciplinaire afin de faciliter la prise en compte des déterminants sociaux de la santé dans l’évaluation.
A distributed brain response predicting the facial expression of acute nociceptive pain
Authors: Picard Marie-Eve , Kunz Miriam , Chen Jen-I , Coll Michel-Pierre , Vachon-Presseau Etienne , Wager Tor D , Rainville Pierre
Published: October 2023

Pain is a private experience observable through various verbal and non-verbal behavioural manifestations, each of which may relate to different pain-related functions. Despite the importance of understanding the cerebral mechanisms underlying those manifestations, there is currently limited knowledge of the neural correlates of the facial expression of pain. In this functional magnetic resonance imaging (fMRI) study, noxious heat stimulation was applied in healthy volunteers and we tested if previously published brain signatures of pain were sensitive to pain expression. We then applied a multivariate pattern analysis to the fMRI data to predict the facial expression of pain. Results revealed the inability of previously developed pain neurosignatures to predict the facial expression of pain. We thus propose a facial expression of pain signature (FEPS) conveying distinctive information about the brain response to nociceptive stimulations with minimal or no overlap with other pain-relevant brain signatures associated with nociception, pain ratings, thermal pain aversiveness, or pain valuation. The FEPS may provide a distinctive functional characterization of the distributed cerebral response to nociceptive pain associated with the socio-communicative role of non-verbal pain expression. This underscores the complexity of pain phenomenology by reinforcing the view that neurosignatures conceived as biomarkers must be interpreted in relation to the specific pain manifestation(s) predicted and their underlying function(s). Future studies should explore other pain-relevant manifestations and assess the specificity of the FEPS against simulated pain expressions and other types of aversive or emotional states.
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans
Authors: Otarigho Benson , Butts Anna Frances , Aballay Alejandro
Published: October 2023

The survival of hosts during infections relies on their ability to mount effective molecular and behavioral immune responses. Despite extensive research on these defense strategies in various species, including the model organism Caenorhabditis elegans, the neural mechanisms underlying their interaction remain poorly understood. Previous studies have highlighted the role of neural G-protein-coupled receptors (GPCRs) in regulating both immunity and pathogen avoidance, which is particularly dependent on aerotaxis. To address this knowledge gap, we conducted a screen of mutants in neuropeptide receptor family genes. We found that loss-of-function mutations in npr-15 activated immunity while suppressing pathogen avoidance behavior. Through further analysis, NPR-15 was found to regulate immunity by modulating the activity of key transcription factors, namely GATA/ELT-2 and TFEB/HLH-30. Surprisingly, the lack of pathogen avoidance of npr-15 mutant animals was not influenced by oxygen levels. Moreover, our studies revealed that the amphid sensory neuron ASJ is involved in mediating the immune and behavioral responses orchestrated by NPR-15. Additionally, NPR-15 was found to regulate avoidance behavior via the TRPM (transient receptor potential melastatin) gene, GON-2, which may sense the intestinal distension caused by bacterial colonization to elicit pathogen avoidance. Our study contributes to a broader understanding of host defense strategies and mechanisms underlining the interaction between molecular and behavioral immune responses.
Ym1 protein crystals promote type 2 immunity
Authors: Heyndrickx Ines , Deswarte Kim , Verstraete Kenneth , Verschueren Koen HG , Smole Ursula , Aegerter Helena , Dansercoer Ann , Hammad Hamida , Savvides Savvas N , Lambrecht Bart N
Published: October 2023

Spontaneous protein crystallization is a rare event, yet protein crystals are frequently found in eosinophil-rich inflammation. In humans, Charcot-Leyden crystals (CLCs) are made from galectin-10 (Gal10) protein, an abundant protein in eosinophils. Although mice do not encode Gal10 in their genome, they do form pseudo-CLCs, made from the chitinase-like proteins Ym1 and/or Ym2, encoded by Chil3 and Chil4 and made by myeloid and epithelial cells respectively. Here, we investigated the biological effects of pseudo-CLCs since their function is currently unknown. We produced recombinant Ym1 crystals which were shown to have identical crystal packing and structure by X-ray crystallography as in vivo native crystals derived from murine lung. When administered to the airways of mice, crystalline but not soluble Ym1 stimulated innate and adaptive immunity and acted as a type 2 immune adjuvant for eosinophilic inflammation via triggering of dendritic cells (DCs). Murine Ym1 protein crystals found at sites of eosinophilic inflammation reinforce type 2 immunity and could serve as a surrogate model for studying the biology of human CLCs.
Increasing adult-born neurons protects mice from epilepsy
Authors: Jain Swati , LaFrancois John J , Gerencer Kasey , Botterill Justin J , Kennedy Meghan , Criscuolo Chiara , Scharfman Helen E
Published: October 2023

Neurogenesis occurs in the adult brain in the hippocampal dentate gyrus, an area that contains neurons which are vulnerable to insults and injury, such as severe seizures. Previous studies showed that increasing adult neurogenesis reduced neuronal damage after these seizures. Because the damage typically is followed by chronic life-long seizures (epilepsy), we asked if increasing adult-born neurons would prevent epilepsy. Adult-born neurons were selectively increased by deleting the pro-apoptotic gene Bax from Nestin-expressing progenitors. Tamoxifen was administered at 6 weeks of age to conditionally delete Bax in Nestin-CreERT2Baxfl/fl mice. Six weeks after tamoxifen administration, severe seizures (status epilepticus; SE) were induced by injection of the convulsant pilocarpine. After mice developed epilepsy, seizure frequency was quantified for 3 weeks. Mice with increased adult-born neurons exhibited fewer chronic seizures. Postictal depression was reduced also. These results were primarily in female mice, possibly because they were more affected by Bax deletion than males, consistent with sex differences in Bax. The female mice with enhanced adult-born neurons also showed less neuronal loss of hilar mossy cells and hilar somatostatin-expressing neurons than wild-type females or males, which is notable because loss of these two hilar cell types is implicated in epileptogenesis. The results suggest that selective Bax deletion to increase adult-born neurons can reduce experimental epilepsy, and the effect shows a striking sex difference. The results are surprising in light of past studies showing that suppressing adult-born neurons can also reduce chronic seizures.
Mining Google Trends data for nowcasting and forecasting colorectal cancer (CRC) prevalence
Authors: Tudor Cristiana , Sova Robert Aurelian
Published: October 2023

Background

Colorectal cancer (CRC) is the third most prevalent and second most lethal form of cancer in the world. Consequently, CRC cancer prevalence projections are essential for assessing the future burden of the disease, planning resource allocation, and developing service delivery strategies, as well as for grasping the shifting environment of cancer risk factors. However, unlike cancer incidence and mortality rates, national and international agencies do not routinely issue projections for cancer prevalence. Moreover, the limited or even nonexistent cancer statistics for large portions of the world, along with the high heterogeneity among world nations, further complicate the task of producing timely and accurate CRC prevalence projections. In this situation, population interest, as shown by Internet searches, can be very important for improving cancer statistics and, in the long run, for helping cancer research.

Methods

This study aims to model, nowcast and forecast the CRC prevalence at the global level using a three-step framework that incorporates three well-established univariate statistical and machine-learning models. First, data mining is performed to evaluate the relevancy of Google Trends (GT) data as a surrogate for the number of CRC survivors. The results demonstrate that population web-search interest in the term “colonoscopy” is the most reliable indicator to nowcast CRC disease prevalence. Then, various statistical and machine-learning models, including ARIMA, ETS, and FNNAR, are trained and tested using relevant GT time series. Finally, the updated monthly query series spanning 2004–2022 and the best forecasting model in terms of out-of-sample forecasting ability (i.e., the neural network autoregression) are utilized to generate point forecasts up to 2025.

Results

Results show that the number of people with colorectal cancer will continue to rise over the next 24 months. This in turn emphasizes the urgency for public policies aimed at reducing the population's exposure to the principal modifiable risk factors, such as lifestyle and nutrition. In addition, given the major drop in population interest in CRC during the first wave of the COVID-19 pandemic, the findings suggest that public health authorities should implement measures to increase cancer screening rates during pandemics. This in turn would deliver positive externalities, including the mitigation of the global burden and the enhancement of the quality of official statistics.
Assessment of different factors on the influence of glass wool concentration for detection of main swine viruses in water samples
Authors: Fan Jie , Chen Hongjian , Song Wenbo , Yang Hao , Xie Rui , Zhao Mengfei , Wu Wenqing , Peng Zhong , Wu Bin
Published: October 2023

Viruses existed in wastewaters might pose a biosecurity risk to human and animal health. However, it is generally difficult to detect viruses in wastewater directly as they usually occur in low numbers in water. Therefore, processing large volumes of water to concentrate viruses in a much smaller final volume for detection is necessary. Glass wool has been recognized as an effective material to concentrate multiple in water, and in this study, we assessed the use of glass wools on concentrating pseudorabies virus (PRV), African swine fever virus (ASFV), and porcine epidemic diarrhea virus (PEDV) in water samples. The influence of pH values, water matrix, water volume, filtration rate, temperature on the effect of the method concentrating these viruses for detection was evaluated in laboratory. Our results revealed that glass wool was suitable for the concentration of above-mentioned viruses from different water samples, and demonstrated a good application effect for water with pH between 6.0–9.0. Furthermore, glass wool also showed a good recovery effect on concentrating viral nucleic acids and viral particles, as well as living viruses. In addition, combining use of glass wool with skim milk, polyethylene glycol (PEG)-NaCl, or ultracentrifuge had good effects on concentrating ASFV, PRV, and PEDV. Detection of wastewater samples (n = 70) collected from 70 pig farms in 13 regions across Hubei Province in Central China after glass-wool-concentration determined one sample positive for ASFV, eighteen samples positive for PRV, but no sample positive for PEDV. However, these positive samples were detected to be negative before glass wool enrichment was implemented. Our results suggest that glass wool-based water concentration method developed in this study represents an effective tool for detecting viruses in wastewater.
Conservadorismo condicional: análise das empresas do novo mercado da B3, em face da adoção da interpretação técnica ICPC 22 - incerteza sobre tratamento de tributos sobre o lucro
Authors: Tricarico Andreia Vergineli , Furtado Priscyla de Moura Lopes , Marques José Augusto Veiga da Costa , Costa Thiago de Abreu
Published: October 2023

O estudo teve como objetivo avaliar o nível de conservadorismo condicional aplicado pelas empresas participantes do segmento Novo Mercado (NM) da B3, em face da interpretação técnica ICPC 22, que trata sobre Incerteza acerca do Tratamento de Tributos sobre o Lucro. Nessa perspectiva, foram selecionadas 37 companhias, utilizando o retorno econômico da ação da empresa como proxy para testar o conservadorismo, considerando suas variações positivas (boas notícias) e negativas (más notícias), conforme o Modelo de Basu (1997). Adicionalmente, foi feita uma adaptação no modelo de Basu, em que foram incorporadas dummies para verificar os impactos da ICPC 22 e os registros das posições fiscais incertas refletidas nos tributos sobre o lucro. Foi efetuada uma análise através de estatística descritiva e regressão de dados em painel. Os resultados indicaram que as empresas da amostra não apresentaram alteração no nível de conservadorismo praticado após a emissão da ICPC 22. Isso significa que a emissão da interpretação técnica ICPC 22 não influenciou na prática do conservadorismo, mantendo os valores dos tributos sobre o lucro praticados pelas empresas participantes do segmento NM, confirmando a hipótese nula formulada neste estudo. A pesquisa contribui para a discussão sobre o nível de conservadorismo empregado pelas empresas em face a obrigatoriedade de evidenciar nas demonstrações contábeis posições fiscais incertas, diante de um regime tributário agressivo, como o praticado no Brasil.
Centro histórico de Salvador, Bahia, Brasil: marca coletiva e territorial para o desenvolvimento sustentável
Authors: Rocha Angela Machado , Guimarães Márcia Magalhães
Published: October 2023

Marcas são sinais distintivos que identificam a origem e distinguem produtos e serviços no mercado. Um tipo específico, a marca coletiva, identifica produtos ou serviços provindos de membros de uma determinada entidade coletiva. O estudo objetiva analisar como uma marca coletiva pode assumir a função de marca de lugar, como expressão da identidade local e como esses conceitos podem ser utilizados para promoção do desenvolvimento sustentável local. Por meio da pesquisa exploratória com abordagem qualitativa, utilizando pesquisa bibliográfica, normativa e documental, concluiu-se uma marca coletiva pode assumir função de marca de lugar que quando o trabalho da entidade representativa da marca encontra-se vinculado a um território, e sua identidade é expressa em seus produtos e serviços.
Percepção moral sob a perspectiva de acadêmicos de ciências contábeis sobre a corrupção no âmbito contábil
Authors: Almeida Sirlene de Aguiar Fernandes , Lemes Sirlei , Lima Ana Claudia Santo
Published: October 2023

O objetivo deste trabalho foi identificar a percepção moral dos estudantes de contabilidade, levando-se em consideração os diferentes tipos de corrupção, os indicadores éticos organizacionais e o papel do profissional contábil na luta anticorrupção. Os dados foram coletados por meio de um questionário aplicado aos discente do curso presencial de Ciências Contábeis da Universidade Federal de Uberlândia (UFU). Os resultados obtidos indicam que os discentes possuem capacidade de conceituar o fenômeno corrupção, mas sinalizam inconsistências morais quanto à percepção das condutas corruptas. Esta pesquisa contribui com a literatura ao cooperar com pesquisas que abordam a percepção de futuros profissionais de contabilidade diante da corrupção, trazendo evidências de como a corrupção é conceituada e a conduta dos discentes diante de atos corruptos.
Assessment of Genetic Diversity Using Metroglyph Analysis in Rice (Oryza sativa L.) Germplasm
Authors: Reddy Y Venkata Narendra , Lal Gabriyal M. , Reddy Paleru Brahmananda
Published: October 2023

The present investigation was carried out to assess the genetic variability parameters, metroglyph analysis in 31 rice genotypes for 13 quantitative traits during Kharif,2022 season at Field experimentation center, Department of Genetics and Plant Breeding, Naini Agricultural Institute, Sam Higginbottom University of Agriculture Technology and Sciences, Uttar Pradesh using Randomized Block Design with three replications. Analysis of variance indicated high significant differences among the genotypes for all the traits. Considerable variability existed in the genotypes for all the characters studied. These were the genotypes with high mean values in desirable direction i.e., From the present investigation it is concluded that among 31 genotypes of rice, VASUMATHI showed Early flowering (80 days), and had characters like Early maturity (113days), DRR DHAN-38 showed high Plant height (155.8 cm), PUSA BASMATHI-1 showed high Panicle length (28.8 cm), NAGARJUNA is showing both high Biomass (69.3 g), and Grain Yield per Plant (39.7 g). Highest GCV were depicted for Grain Yield per Plant, Biological Yield per hill, Number of Spikelet’s per panicle, Number of Panicles per hill, Number of Tillers per Hill, and Flag Leaf Width. The highest Heritability was observed for Number of Tillers per hill, Number of Spikelet’s per Panicle, Grain yield per plant, Number of Panicles per hill, Biological Yield per Hill and Flag Leaf Width and Highest genetic advance as a percentage of mean except Plant height, Grain yield per plant, Biological yield per hill, Number of spikelet’s per panicle, Number of panicles per hill, Number of total tillers, Flag leaf width and harvest index. A scatter diagram was created for 31 genotypes that formed five complexes with 13,9,4,4 and 1 genotype in each complex. The genotypes Nagarjuna, Jarva and NDR-359, which have a high index score and fall into various clusters, can be utilized as parents in hybridization to get the most variety in character combinations. This character should be given due consideration during selection for crop improvement.
Woman in Her 50s With an Intravenous Mass Extending to the Right Cardiac Chamber
Authors: Li Jiehua , Li Quanming , Shu Chang
Published: October 2023

This case report describes a diagnosis of intravenous leiomyomatosis in a woman in her 50s who presented with exertional dyspnea and syncope and had a history of hysteromyomectomy.
Extravasation of Iodine Contrast
Authors: Corbella-Bagot Lluís , Luque-Luna Mar
Published: October 2023

This case report describes an older man with acute ischemic stroke who developed painful lesions around the intravenous line.
Prevalence and Trends in Diagnosed ADHD Among US Children and Adolescents, 2017-2022
Authors: Li Yanmei , Yan Xiaofang , Li Qishan , Li Qian , Xu Guifeng , Lu Jinhua , Yang Wenhan
Published: October 2023

This cross-sectional study estimates prevalence and trends of ADHD diagnosis among US children and adolescents from 2017 to 2022.
Prevalence of Autism Among Medicaid-Enrolled Adults
Authors: Rubenstein Eric , Tewolde Salina , Michals Amy , Fox Matthew , Wang Na
Published: October 2023

Importance

The reported prevalence of autism in children has consistently risen over the past 20 years. The concurrent implications for the adult Medicaid system, which insures autistic adults due to low income or disability, have not been studied.

Objective

To estimate the prevalence of adults identified as autistic in Medicaid claims data and to examine the prevalence by year, age, and race and ethnicity to understand enrollment patterns.

Design, Setting, and Participants

This cohort study used data from a longitudinal Medicaid claims cohort of enrollees aged 18 years or older with a claim for autism at any point from January 1, 2011, to December 31, 2019, and an approximately 1% random sample of all adult Medicaid enrollees. The data were analyzed between February 22 and June 22, 2023.

Exposure

Adults enrolled in Medicaid with a claim for autism.

Main Outcome and Measures

Prevalence of autism per 1000 Medicaid enrollees for each year was calculated using denominator data from the Centers for Medicare & Medicaid Services weighted to nondisabled population demographic characteristics. Prevalence by race and ethnicity were calculated for study year 2019.

Results

Across 9 years, 403 028 unique adults had autism claims in their Medicaid records (25.7% female, 74.2% male, 3.3% Asian, 16.8% Black, 12.2% Hispanic, 0.8% Native American, 0.8% Pacific Islander, 74.3% White, and 4.2% of multiple races). Across all ages, autism prevalence increased from 4.2 per 1000 enrollees in 2011 to 9.5 per 1000 enrollees in 2019. The largest increase over the 9 years was in the 25- to 34-year age group (195%), and the smallest increase was in the 55- to 64-year age group (45%). The prevalence of White enrollees was at least 2 times that of the prevalence of every other racial group in all age categories.

Conclusions and Relevance

The study findings suggest that despite difficulties in identifying autism in adults, there is a considerable and growing population of autistic adults enrolled in Medicaid. As children on the autism spectrum become autistic adults, Medicaid is an important insurance provider for an increasing number of autistic adults and can be a valuable resource for understanding the health of the autistic population.
AAPM Medical Physics Practice Guideline 8.b: Linear accelerator performance tests
Authors: Krauss Robert F. , Balik Salim , Cirino Eileen T. , Hadley Austin , Hariharan Navneeth , Holmes Shannon M. , Kielar Kayla , Lavvafi Hossein , McCullough Kiernan , Palefsky Steven , Sawyer J. Phillip , Smith Koren , Tracy Jason , Winter Jeff D. , Wingreen Nicholai E.
Published: October 2023

The purpose of this guideline is to provide a list of critical performance tests to assist the Qualified Medical Physicist (QMP) in establishing and maintaining a safe and effective quality assurance (QA) program. The performance tests on a linear accelerator (linac) should be selected to fit the clinical patterns of use of the accelerator and care should be given to perform tests which are relevant to detecting errors related to the specific use of the accelerator. Current recommendations for linac QA were reviewed to determine any changes required to those tests highlighted by the original report as well as considering new components of the treatment process that have become common since its publication. Recommendations are made on the acquisition of reference data, routine establishment of machine isocenter, basing performance tests on clinical use of the linac, working with vendors to establish QA tests and performing tests after maintenance and upgrades. The recommended tests proposed in this guideline were chosen based on consensus of the guideline's committee after assessing necessary changes from the previous report. The tests are grouped together by class of test (e.g., dosimetry, mechanical, etc.) and clinical parameter tested. Implementation notes are included for each test so that the QMP can understand the overall goal of each test. This guideline will assist the QMP in developing a comprehensive QA program for linacs in the external beam radiation therapy setting. The committee sought to prioritize tests by their implication on quality and patient safety. The QMP is ultimately responsible for implementing appropriate tests. In the spirit of the report from American Association of Physicists in Medicine Task Group 100, individual institutions are encouraged to analyze the risks involved in their own clinical practice and determine which performance tests are relevant in their own radiotherapy clinics.
A “Polymer‐in‐Salt” Solid Electrolyte Enabled by Fast Phase Transition Route for Stable Zn Batteries
Authors: Yan Kang , Fan Yongbo , Hu Fulong , Li Gang , Yang Xueya , Wang Xinyu , Li Xiaomin , Peng Chao , Wang Weijia , Fan Huiqing , Ma Longtao
Published: October 2023

Solid polymer electrolyte‐based batteries show great promise because of their safe operating properties, wide voltage window and suitable flexibility. However, low ionic conductivity, low cation transfer number, weak oxidation/reduction resistance and low mechanical strength limit their implementation in Zn ion batteries. Here, w e developed a “polymer‐in‐salt” Zn2+‐conductive solid electrolyte (denoted as 70% salt‐SPE) constructed by a simple and fast phase transition method. The room‐temperature ionic conductivity and the transfer number of the 70% salt‐SPE reaches 1.6 mS cm−1 and 0.78, respectively. Meanwhile, the ZnF2‐rich inorganic/organic hybrid solid electrolyte interface is formed, and the stable voltage window reaches 9.35 V. In consequence, the Zn||Zn symmetric cell continuously cycles over 700 hours at current density of 2 mA cm−2 and the Zn||Cu symmetric battery runs with Coulombic efficiency of >99%. The Zn||MnPBA full battery delivers a discharge specific capacity of 109 mAh g−1 at room temperature and 190 mAh g−1 at 60 °C. Meanwhile, impressive cyclic stability of 6000 cycles with capacity retention of 80% is achieved, which originates from the effectively optimized ion transport action and dendrite‐free Zn plating/stripping.
Enhancement of Thermoelectric Performance in Robust ZnO‐Based Composite Ceramics Driven by A Stepwise Optimization Strategy
Authors: Wang Dianzhen , Gao Yuqi , You Cun , Cheng Jiaen , Liu Zeben , Qiang Yuhan , Lian Min , Ma Xiaoci , Ge Yufei , Chen Yanli , Tao Qiang , Zhu Pinwen
Published: October 2023

ZnO is a promising high‐temperature thermoelectric (TE) material due to its superior stability and earth abundance. However, the coupling relation between Seebeck coefficient and electrical conductivity on carrier concentration limits the optimum TE performance for most TE materials, especially ZnO. Herein, enhancement of TE performance is achieved via a stepwise optimization strategy composed of carrier concentration optimization and carrier filtering effect for fabricating robust ZnO‐based composite ceramics through a self‐developed specific high‐pressure synthesis followed by spark plasma sintering. Specifically, doping SnO2 provide substantial electrons to surge the carrier concentration. The subsequent compositing Si3N4 nanoparticles results in the unique reaction‐generated Zn2SiO4 nanoprecipitates with a larger bandgap and intrinsically low thermal conductivity, which introduce an excellent carrier filtering effect to increase the Seebeck coefficient by 57.7% at 300 K without compromising electrical conductivity much and enhance phonon scattering to cause an ultralow lattice thermal conductivity of 1.39 W m−1 K−1 achieving amorphous limits of ZnO (1.4±0.1 W m−1 K−1). Consequently, a high peak ZT (figure of merit) of 0.691 at 873 K is obtained, which is higher than that of previously reported ZnO‐based TE materials. This work demonstrates a feasible and effective strategy to fabricate high‐performance TE materials, especially those with inferior electrical conductivity.
Rare‐Earth‐Free Mn30Fe20−xCuxAl50 Magnetocaloric Materials with Stable Cubic CsCl‐Type Structure for Room‐Temperature Refrigeration
Authors: Zhang Yikun , Hao Weixiang , Hu Chenglong , Wang Xing , Zhang Xuefeng , Li Lingwei
Published: October 2023

Magnetic refrigeration technology based on the magnetocaloric effect (MCE) of magnetic substances has been considered a prominent, energy‐efficient, and environmentally benign cooling method. Exploring suitable magnetic substances is a prerequisite for practical applications. A family of rare‐earth‐free magnetocaloric materials called Mn30Fe20−xCuxAl50 alloys is identified room‐temperature refrigeration, which are derived from the well‐known MnAl‐based permanent magnets. As expected from experimental and theoretical investigations, all of the Mn30Fe20−xCuxAl50 alloys are crystallized in a stable cubic CsCl‐type crystal structure, revealing a single second‐order type magnetic phase transition (MPT) with tunable MPT temperature. They also exhibit a large reversible MCE and good magnetocaloric performances in a wide temperature range. Crucially, these Mn30Fe20−xCuxAl50 alloys represent a rare case of magnetic materials belonging to a large family that can be fabricated from low‐price, earth‐abundant, and non‐toxic elements. They could provide new choices for practical room‐temperature magnetic refrigeration applications.