bluuebunny/crossref_metadata_2025 huggingface dataset:
Insulated transcriptional elements enable precise design of genetic circuits
Authors: Zong Yeqing , Zhang Haoqian M. , Lyu Cheng , Ji Xiangyu , Hou Junran , Guo Xian , Ouyang Qi , Lou Chunbo
Published: June 2017

Rational engineering of biological systems is often complicated by the complex but unwanted interactions between cellular components at multiple levels. Here we address this issue at the level of prokaryotic transcription by insulating minimal promoters and operators to prevent their interaction and enable the biophysical modeling of synthetic transcription without free parameters. This approach allows genetic circuit design with extraordinary precision and diversity, and consequently simplifies the design-build-test-learn cycle of circuit engineering to a mix-and-match workflow. As a demonstration, combinatorial promoters encoding NOT-gate functions were designed from scratch with mean errors of <1.5-fold and a success rate of >96% using our insulated transcription elements. Furthermore, four-node transcriptional networks with incoherent feed-forward loops that execute stripe-forming functions were obtained without any trial-and-error work. This insulation-based engineering strategy improves the resolution of genetic circuit technology and provides a simple approach for designing genetic circuits for systems and synthetic biology.
The beetle elytron plate: a lightweight, high-strength and buffering functional-structural bionic material
Authors: Zhang Xiaoming , Xie Juan , Chen Jinxiang , Okabe Yoji , Pan Longcheng , Xu Mengye
Published: June 2017

To investigate the characteristics of compression, buffering and energy dissipation in beetle elytron plates (BEPs), compression experiments were performed on BEPs and honeycomb plates (HPs) with the same wall thickness in different core structures and using different molding methods. The results are as follows: 1) The compressive strength and energy dissipation capacity in the BEP are 2.44 and 5.0 times those in the HP, respectively, when the plates are prepared using the full integrated method (FIM). 2) The buckling stress is directly proportional to the square of the wall thickness (t). Thus, for core structures with equal wall thicknesses, although the core volume of the BEP is 42 percent greater than that of the HP, the mechanical properties of the BEP are several times higher than those of the HP. 3) It is also proven that even when the single integrated method (SIM) is used to prepare BEPs, the properties discussed above remain superior to those of HPs by a factor of several; this finding lays the foundation for accelerating the commercialization of BEPs based on modern manufacturing processes.
Pyrocurrent anomalies and intrinsic magnetodielectric behavior near room temperature in Li2Ni2Mo3O12, a compound with distorted honeycomb and spin-chains
Authors: Upadhyay Sanjay Kumar , Iyer Kartik K. , Gohil Smita , Ghosh Shankar , Paulose P. L. , Sampathkumaran E. V.
Published: June 2017

Keeping current interests to identify materials with intrinsic magnetodielectric behaviour near room temperature and with novel pyroelectric current anomalies, we report temperature and magnetic-field dependent behavior of complex dielectric permittivity and pyroelectric current for an oxide, Li2Ni2Mo3O12, containing magnetic ions with (distorted) honey-comb and chain arrangement and ordering magnetically below 8 K. The dielectric data reveal the existence of relaxor ferroelectricity behaviour in the range 160–240 K and there are corresponding Raman mode anomalies as well in this temperature range. Pyrocurrent behavior is also consistent with this interpretation, with the pyrocurrent peak-temperature interestingly correlating with the poling temperature. 7Li NMR offer an evidence for crystallographic disorder intrinsic to this compound and we therefore conclude that such a disorder is apparently responsible for the randomness of local electric field leading to relaxor ferroelectric property. Another observation of emphasis is that there is a notable decrease in the dielectric constant with the application of magnetic field to the tune of about −2.4% at 300 K, with the magnitude varying marginally with temperature. Small loss factor values validate the intrinsic behaviour of the magnetodielectric effect at room temperature.
Novel carbon quantum dots from egg yolk oil and their haemostatic effects
Authors: Zhao Yan , Zhang Yue , Liu Xiaoman , Kong Hui , Wang Yongzhi , Qin Gaofeng , Cao Peng , Song Xingxing , Yan Xin , Wang Qingguo , Qu Huihua
Published: June 2017

In this study, the properties of egg yolk oil (EYO) were investigated. Water extraction, dialysis, and ultrafiltration were used to extract and purify EYO, and microscopy, spectrophotometry, and chromatography were used to identify carbon dots (CDs) present in EYO (EYO CDs). Morphology analyses demonstrated that CDs were almost spherical, with an average size of <10 nm, a lattice spacing of 0.267 nm, and a composition of mainly C, O, and Fe. The solution showed bright blue fluorescence at 365 nm. Tail haemorrhaging and liver haemorrhaging experiments showed that CD-treated mice had significantly shorter bleeding times than did control mice. Coagulation assays suggested that EYO CDs stimulate the intrinsic blood coagulation system and activate the fibrinogen system. Thus, EYO CDs possess the ability to activate haemostasis, which may lead to further investigations of this ingredient of traditional Chinese medicine.
Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis
Authors: Meng Zengdong , Yu Jing , Luo Chong , Liu Xia , Jiang Wei , Yu Lehua , Huang Rongzhong
Published: June 2017

Aim of this study was to evaluate the effect of cervical spondylosis surgery on cervical lordosis and to identify factors affecting the change by latest follow-up. Literature search was carried out in electronic databases and study selection followed a priori eligibility criteria. Random effects meta-analyses were performed to estimate effect size/s of change in lordosis after surgery (at latest follow-up) and metaregression analyses were performed to identify factors affecting this change. Nineteen studies (1845 patients; age 55.18 [95% CI: 54.78, 55.57] years; 60.99 [60.63, 61.36] % males; follow-up 25.59 [25.20, 25.99] months) were included. Whereas, corpectomy (4.06 [2.65, 5.46] degree; p < 0.00001) and discectomy (4.59 [2.07, 7.11] degree; p < 0.00001) were associated with increase, laminectomy (−1.87 [−8.40, 4.66] degree; p = 0.57) and laminoplasty (0.25 [−1.07, 1.56] degree; p = 0.711) were not associated with significant change in lordosis at latest follow-up. Change in Japanese Orthopedic Association (JOA)/modified JOA (mJOA) score at latest follow-up was also significantly (p = 0.0005) higher in anterior than in posterior surgery group. Change in lordosis at latest follow-up had significant positive relationship with follow-up duration but had significant inverse associations with age, male gender, and preoperative JOA/mJOA score, independently. In posterior surgery subjects, after adjusting for age and gender, preoperative JOA/mJOA score was significantly inversely related to change in lordosis.
Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
Authors: Revêchon Gwladys , Viceconte Nikenza , McKenna Tomás , Sola Carvajal Agustín , Vrtačnik Peter , Stenvinkel Peter , Lundgren Torbjörn , Hultenby Kjell , Franco Irene , Eriksson Maria
Published: June 2017

Accumulation of progerin is believed to underlie the pathophysiology of Hutchinson-Gilford progeria syndrome, a disease characterized by clinical features suggestive of premature aging, including loss of subcutaneous white adipose tissue (sWAT). Although progerin has been found in cells and tissues from apparently healthy individuals, its significance has been debated given its low expression levels and rare occurrence. Here we demonstrate that sustained progerin expression in a small fraction of preadipocytes and adipocytes of mouse sWAT (between 4.4% and 6.7% of the sWAT cells) results in significant tissue pathology over time, including fibrosis and lipoatrophy. Analysis of sWAT from mice of various ages showed senescence, persistent DNA damage and cell death that preceded macrophage infiltration, and systemic inflammation. Our findings suggest that continuous progerin expression in a small cell fraction of a tissue contributes to aging-associated diseases, the adipose tissue being particularly sensitive.
Super-hydrophobic multilayer coatings with layer number tuned swapping in surface wettability and redox catalytic anti-corrosion application
Authors: Syed Junaid Ali , Tang Shaochun , Meng Xiangkang
Published: June 2017

The wetting characteristic of a metal surface can be controlled by employing different coating materials and external stimuli, however, layer number (n) modulated surface swapping between hydrophobicity and hydrophilicity in a multilayer structure to achieve prolonged anti-corrosion ability was not taken into consideration. In this study, we proposed a layer-by-layer (LbL) spin assembled polyaniline-silica composite/tetramethylsilane functionalized silica nanoparticles (PSC/TMS-SiO2) coating with the combined effect of super-hydrophobicity and enhanced anti-corrosion ability. Interestingly, the hierarchical integration of two coating materials with inherently different surface roughness and energy in a multilayer structure allows the wetting feature to swap from hydrophobic to hydrophilic state by modulating n with decreasing hydrophilicity. The samples with odd n (TMS-SiO2 surface) are hydrophobic while the samples with even n (PSC surface) exhibits the hydrophilic character. The TMS-SiO2 content was optimized to achieve super-hydrophobic coating with significantly high water contact angle (CA) 153° ± 2° and small sliding angle (SA) 6° ± 2°. Beside its self-cleaning behavior, the electro-active PSC/TMS-SiO2 coating also exhibits remarkably enhanced corrosion resistance against aggressive media. The corrosion resistance of the coating was remained stable even after 240 h of exposure, this enhancement is attributed to super-hydrophobicity and anodic shift in corrosion potential.
The Specific Vulnerabilities of Cancer Cells to the Cold Atmospheric Plasma-Stimulated Solutions
Authors: Yan Dayun , Cui Haitao , Zhu Wei , Nourmohammadi Niki , Milberg Julian , Zhang Lijie G. , Sherman Jonathan H. , Keidar Michael
Published: June 2017

Cold atmospheric plasma (CAP), a novel promising anti-cancer modality, has shown its selective anti-cancer capacity on dozens of cancer cell lines in vitro and on subcutaneous xenograft tumors in mice. Over the past five years, the CAP-stimulated solutions (PSS) have also shown their selective anti-cancer effect over different cancers in vitro and in vivo. The solutions used to make PSS include several bio-adaptable solutions, mainly cell culture medium and simple buffered solutions. Both the CAP-stimulated medium (PSM) and the CAP-stimulated buffered solution (PSB) are able to significantly kill cancer cells in vitro. In this study, we systematically compared the anti-cancer effect of PSM and PSB over pancreatic adenocarcinoma cells and glioblastoma cells. We demonstrated that pancreatic cancer cells and glioblastoma cells were specifically vulnerable to PSM and PSB, respectively. The specific response such as the rise of intracellular reactive oxygen species of two cancer cell lines to the H2O2-containing environments might result in the specific vulnerabilities to PSM and PSB. In addition, we demonstrated a basic guideline that the toxicity of PSS on cancer cells could be significantly modulated through controlling the dilutability of solution.
Circulating Biomarkers to Identify Responders in Cardiac Cell therapy
Authors: Jokerst Jesse V. , Cauwenberghs Nicholas , Kuznetsova Tatiana , Haddad Francois , Sweeney Timothy , Hou Jiayi , Rosenberg-Hasson Yael , Zhao Eric , Schutt Robert , Bolli Roberto , Traverse Jay H. , Pepine Carl J. , Henry Timothy D. , Schulman Ivonne H. , Moyé Lem , Taylor Doris A. , Yang Phillip C.
Published: June 2017

Bone marrow mononuclear cell (BM-MNC) therapy in ST-elevation acute myocardial infarction (STEMI) has no biological inclusion criteria. Here, we analyzed 63 biomarkers and cytokines in baseline plasma samples from 77 STEMI patients treated with BM-MNCs in the TIME and Late-TIME trials as well as 61 STEMI patients treated with placebo. Response to cell therapy was defined by changes in left ventricular ejection fraction, systolic/diastolic volumes, and wall motion indexes. We investigated the clinical value of circulating proteins in outcome prediction using significance testing, partial least squares discriminant analysis, and receiver operating characteristic (ROC) analysis. Responders had higher biomarker levels (76–94% elevated) than non-responders. Several biomarkers had values that differed significantly (P < 0.05) between responders and non-responders including stem cell factor, platelet-derived growth factor, and interleukin-15. We then used these lead candidates for ROC analysis and found multiple biomarkers with values areas under the curve >0.70 including interleukin 15. These biomarkers were not involved in the placebo-treated subjects suggesting that they may have predictive power. We conclude that plasma profiling after STEMI may help identify patients with a greater likelihood of response to cell-based treatment. Prospective trials are needed to assess the predictive value of the circulating biomarkers.
ANKRD22 promotes progression of non-small cell lung cancer through transcriptional up-regulation of E2F1
Authors: Yin Jun , Fu Wenfan , Dai Lu , Jiang Zeyong , Liao Hongying , Chen Wenbin , Pan Lei , Zhao Jian
Published: June 2017

Lung cancer is the leading cause of death among all malignancies due to rapid tumor progression and relapse; however, the underlying molecular mechanisms of tumor progression are unclear. In the present study, we identified ANKRD22 as a novel tumor-associated gene in non-small cell lung cancer (NSCLC). According to the clinical correlation analysis, ANKRD22 was highly expressed in primary cancerous tissue compared with adjacent cancerous tissue, and high expression levels of ANKRD22 were significantly correlated with relapse and short overall survival time. Knockdown and overexpression analysis revealed that ANKRD22 promoted tumor progression by increasing cell proliferation. In xenograft assays, knockdown of ANKRD22 or in vivo treatment with ANKRD22 siRNA inhibited tumor growth. Furthermore, ANKRD22 was shown to participate in the transcriptional regulation of E2F1, and ANKRD22 promoted cell proliferation by up-regulating the expression of E2F1 which enhanced cell cycle progression. Therefore, our studies indicated that ANKRD22 up-regulated the transcription of E2F1 and promoted the progression of NSCLC by enhancing cell proliferation. These findings suggest that ANKRD22 could potentially act as a novel therapeutic target for NSCLC.
Sedimentation and mobility of PDCs: a reappraisal of ignimbrites’ aspect ratio
Authors: Giordano Guido , Doronzo Domenico M.
Published: June 2017

The aspect ratio of ignimbrites is a commonly used parameter that has been related to the energy of the parent pyroclastic density currents (PDCs). However this parameter, calculated as the ratio between the average thickness and the average lateral extent of ignimbrites, does not capture fundamental differences in pyroclastic flow mobility nor relates to lithofacies variations of the final deposits. We herein introduce the “topological aspect ratio” (ARt) as the ratio of the local deposit thickness (Ht) to the distance between the local site and the maximum runout distance (Lt), where Ht is a proxy for the PDC tendency to deposit, and Lt a proxy for the PDC mobility or its tendency to further transport the pyroclastic material. The positive versus negative spatial gradient d(ARt)/dx along flow paths discriminate zones where PDCs are forced (i.e. where they transport the total energy under the action of mass discharge rate) from zones where they are inertial (i.e. where they transport the total energy under the action of viscous or turbulent fluidization). Though simple to apply, the topological aspect ratio and its spatial gradient are powerful descriptors of the interplay between sedimentation and mobility of PDCs, and of the resulting lithofacies variations.
In situ synthesis of electroactive conjugated microporous fullerene films capable of supercapacitive energy storage
Authors: Sun Mingxiao , Kuang Puxing , Qin Leiqiang , Gu Cheng , Xie Zengqi , Ma Yuguang
Published: June 2017

We describe a general strategy for synthesizing conjugated microporous fullerene thin films via a high-throughput, efficient and controllable thiophene-based electropolymerization.
Instrument-free quantitative gold nanoparticle-based liquid-phase colorimetric assays for use in resource-poor environments
Authors: Wang Huili , Zhang Yun , Li Rongxing , Nie Jinfang , El-Sagheer Afaf H. , Brown Tom , Liu Zhaoying , Xiao Wencheng
Published: June 2017

This work describes a new class of gold nanoparticle-based liquid-phase colorimetric assay (GNP-LPCA) termed as two dimensional (2D) GNP-LPCA that enables quantitative detection of model analytes with naked eye.
Stepwise, multicomponent assembly of a molecular trapezoid possessing three different metals
Authors: Yao Yuchen , Chakraborty Sourav , Zhu Shiying , Endres Kevin J. , Xie Ting-Zheng , Hong Wei , Manandhar Erendra , Moorefield Charles N. , Wesdemiotis Chrys , Newkome George R.
Published: June 2017

A novel terpyridine-based, trapezoidal architecture was synthesized by a coordination-driven multicomponent assembly and features three different tpy–M2+–tpy bonds (M2+ = Ru2+, Fe2+, and Zn2+) in the macrocyclic ring.
Cu overlayers on tetrahexahedral Pd nanocrystals with high-index facets for CO2 electroreduction to alcohols
Authors: Zhang Feng-Yang , Sheng Tian , Tian Na , Liu Li , Xiao Chi , Lu Bang-An , Xu Bin-Bin , Zhou Zhi-You , Sun Shi-Gang
Published: June 2017

Cu overlayers on tetrahexahedral Pd nanocrystals with {310} high-index facets exhibit a high Faradaic efficiency towards alcohols for CO2 electroreduction.
H2 evolution catalyzed by a FeFe-hydrogenase synthetic model covalently attached to graphite surfaces
Authors: Ahmed Md Estak , Dey Subal , Mondal Biswajit , Dey Abhishek
Published: June 2017

A Fe–Fe hydrogenase model is covalently attached to graphite electrodes using a modular approach.
Metallomicelle templated transition metal nanostructures: synthesis, characterization, DFT study and catalytic activity
Authors: Kaur Ravneet , Mehta S. K.
Published: June 2017

A simple and versatile protocol to achieve surface-modified catalytically efficient nanoparticles employing metallosurfactants as excellent scaffolds has been reported.
Vibronic coupling in organic semiconductors for photovoltaics
Authors: De Sio Antonietta , Lienau Christoph
Published: June 2017

Ultrafast two-dimensional electronic spectroscopy reveals vibronically-assisted coherent charge transport and separation in organic materials and opens up new perspectives for artificial light-to-current conversion.
Combining two redox active rare earth elements for oxygen storage – electrical properties and defect chemistry of ceria–praseodymia single crystals
Authors: Michel Kathrin , Eufinger Jens-Peter , Ulbrich Gregor , Lerch Martin , Janek Juergen , Elm Matthias T.
Published: June 2017

The electrochemical properties of (Ce,Pr)O2 single crystals were characterized to obtain reference data for the bulk system.
The temperature behavior and mechanism of exciton luminescence in quantum dots
Authors: Zatsepin A. F. , Biryukov D. Yu.
Published: June 2017

The luminescence and energy parameters of confined excitons depend on the dimensional and structural factors in QDs.
Mechanisms of carbon monoxide hydrogenation yielding formaldehyde catalyzed by the representative strong mineral acid, H2SO4, and Lewis–Brønsted superacid, HF/AlF3
Authors: Rybacka Olimpia , Czapla Marcin , Skurski Piotr
Published: June 2017

The HAlF4 superacid was predicted to effectively reduce the activation barriers of the carbon monoxide hydrogenation mechanism.
Synthesis, characterization and in vitro and in vivo photodynamic activities of a gallium(iii) tris(ethoxycarbonyl)corrole
Authors: Zhang Zhao , Wang Hua-Hua , Yu Hua-Jun , Xiong Yu-Zhen , Zhang Hai-Tao , Ji Liang-Nian , Liu Hai-Yang
Published: June 2017

A gallium(iii) tris(ethoxycarbonyl)corrole is a highly effective photosensitizer against A549 cancer cellsviap38 MAPK signaling cascade pathways.
The underlying factors controlling the Pd-catalyzed site-selective alkenylation of aliphatic amines
Authors: Xing Yang-Yang , Liu Jian-Biao , Sun Chuan-Zhi , Huang Fang , Chen De-Zhan
Published: June 2017

DFT calculations have been performed to elucidate the underlying factors controlling the Pd-catalyzed site-selective alkenylation of aliphatic amines.
Towards the liquid phase exfoliation of bismuth iodide
Authors: Heidary N. , Beyer A. , Volz K. , Heine J.
Published: June 2017

We present first steps towards an effective liquid phase exfoliation of bismuth(iii) iodide, a semiconductor with potential as a photovoltaic absorber material.
Synthesis, characterization and solution behavior of a systematic series of pentapyridyl-supported RuII complexes: comparison to bimetallic analogs
Authors: Park Sungho V. , Berry John F.
Published: June 2017

A series of pentapyridyl-supported Ru(ii) complexes are synthesized and characterized using X-ray crystallography, UV-Vis, 1H NMR and cyclic voltammetry. Moreover, these monometallic species are compared with previously reported bimetallic analogues with regards to their structure and ligand substitution behavior.
Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C–H functionalisation
Authors: Chirila Paula G. , Whiteoak Christopher J.
Published: June 2017

This perspective highlights recent applications of Cp*CoIII catalysts in C–H functionalisation protocols, exemplifying both terminal couplings and heterocycle formation.
Selective palladium-catalysed synthesis of diesters: alkoxycarbonylation of a CO2-butadiene derived δ-lactone
Authors: Ferretti Francesco , Sharif Muhammad , Dastgir Sarim , Ragaini Fabio , Jackstell Ralf , Beller Matthias
Published: June 2017

A selective domino reaction has been developed for the valorization of a well-known δ-lactone synthesized by the telomerization of 1,3-butadiene and CO2.
Understanding the mechanism of enhanced charge separation and visible light photocatalytic activity of modified wurtzite ZnO with nanoclusters of ZnS and graphene oxide: from a hybrid density functional study
Authors: Opoku Francis , Govender Krishna Kuben , van Sittert Cornelia Gertina Catharina Elizabeth , Govender Penny Poomani
Published: June 2017

A hybrid ternary ZnS/GO/ZnO(001) system achieved enough driving force for splitting water into H2gas.
Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights
Authors: Masschelein J. , Jenner M. , Challis G. L.
Published: June 2017

Gram-negative bacteria are a rich and underexplored source of antibiotics that are assembledviaremarkably diverse biosynthetic pathways.
Insulated molecular wires: inhibiting orthogonal contacts in metal complex based molecular junctions
Authors: Al-Owaedi Oday A. , Bock Sören , Milan David C. , Oerthel Marie-Christine , Inkpen Michael S. , Yufit Dmitry S. , Sobolev Alexandre N. , Long Nicholas J. , Albrecht Tim , Higgins Simon J. , Bryce Martin R. , Nichols Richard J. , Lambert Colin J. , Low Paul J.
Published: June 2017

‘Short circuits’ to ancillary ligands in metal complex molecular wires are identified and ‘insulated wires’ presented.
Novel nanoparticles with Cr3+ substituted ferrite for self-regulating temperature hyperthermia
Authors: Zhang Wei , Zuo Xudong , Niu Ying , Wu Chengwei , Wang Shuping , Guan Shui , Silva S. Ravi P.
Published: June 2017

Cr3+ was substituted into Co–Zn ferrite to adjust the Curie temperature and coercivity for self-regulating hyperthermia temperature.
Fluorine-containing bistolanes as light-emitting liquid crystalline molecules
Authors: Yamada Shigeyuki , Miyano Kazuya , Konno Tsutomu , Agou Tomohiro , Kubota Toshio , Hosokai Takuya
Published: June 2017

Fluorine-containing dissymmetric bistolanes were found to be promising light-emitting liquid crystals, which could switch luminescence depending on molecular aggregations.
13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions
Authors: Lohans Christopher T. , Wang David Y. , Jorgensen Christian , Cahill Samuel T. , Clifton Ian J. , McDonough Michael A. , Oswin Henry P. , Spencer James , Domene Carmen , Claridge Timothy D. W. , Brem Jürgen , Schofield Christopher J.
Published: June 2017

13C-NMR spectroscopy is a valuable tool for investigating the mechanisms of inhibitors of the clinically relevant OXA β-lactamases.
(−)-Epigallocatechin-3-gallate (EGCG) inhibits fibrillation, disaggregates amyloid fibrils of α-synuclein, and protects PC12 cells against α-synuclein-induced toxicity
Authors: Zhao Juan , Liang Qingnan , Sun Qing , Chen Congheng , Xu Lihui , Ding Yu , Zhou Ping
Published: June 2017

EGCG protects transduced PC12 cells against α-Syn-induced cytotoxicity by inhibiting the overexpression and fibrillation of α-Syn in the cells.
Molecular interactions between DOPA and surfaces with different functional groups: a chemical force microscopy study
Authors: Zhang Wei , Yang Hui , Liu Fanghui , Chen Ting , Hu Guangxin , Guo Donghong , Hou Qingfeng , Wu Xu , Su Yu , Wang Jinben
Published: June 2017

The adhesion of mussel foot proteins (Mfps) to a variety of surfaces has been widely investigated, but the mechanisms behind the mussel adhesion to surfaces with different properties are far from being understood.
Cellulose nanocrystals as host matrix and waveguide materials for recyclable luminescent solar concentrators
Authors: Chowdhury Farsad Imtiaz , Dick Carson , Meng Lingju , Mahpeykar Seyed Milad , Ahvazi Behzad , Wang Xihua
Published: June 2017

We report the use of an ecofriendly and recyclable CNC material as the host matrix for luminescent solar concentrator applications.
X-ray circular dichroism signals: a unique probe of local molecular chirality
Authors: Zhang Yu , Rouxel Jérémy R. , Autschbach Jochen , Govind Niranjan , Mukamel Shaul
Published: June 2017

X-ray circular dichroism (XCD) spectroscopy provides a powerful tool to detect subtle electronic structures of chiral molecules.
CoOx nanoparticle anchored on sulfonated-graphite as efficient water oxidation catalyst
Authors: Guan Jingqi , Ding Chunmei , Chen Ruotian , Huang Baokun , Zhang Xianwen , Fan Fengtao , Zhang Fuxiang , Li Can
Published: June 2017

Ultrasmall CoOx nanoparticles on sulfonated graphite exhibit highly efficient water oxidation activity and can be used for electrochemical and solar water oxidation.
The mechanical properties of polymer–colloid hybrid hydrogels
Authors: Dehne H. , Hecht F. M. , Bausch A. R.
Published: June 2017

The incorporation of monodisperse colloidal particles in hydrogels is a promising approach to create hybrid gels with unique structural, mechanical and functional properties.
Supramolecular polymer hydrogels induced by host–guest interactions with di-[cyclobis(paraquat-p-phenylene)] cross-linkers: from molecular complexation to viscoelastic properties
Authors: Fumagalli Matthieu , Belal Khaled , Guo Hui , Stoffelbach François , Cooke Graeme , Marcellan Alba , Woisel Patrice , Hourdet Dominique
Published: June 2017

Host–guest interactions between di-[cyclobis(paraquat-p-phenylene)], BB, and poly(N,N-dimethylacrylamide-co-naphthalene acrylamide), P(DMA-N1).
Pore space partition via secondary metal ions entrapped by pyrimidine hooks: influences on structural flexibility and carbon dioxide capture
Authors: Lu Zhiyong , Zhang Jianfeng , Duan Jingui , Du Liting , Hang Cheng
Published: June 2017

A new way of pore space partitionviasecondary metal ions entrapped by pyrimidine hooks is implemented on flexible MOFs.
Electrocatalytic water oxidation at low energy cost by a highly active and robust calcium–manganese oxide thin film sintered on an FTO electrode with ethyl methyl imidazolium triflate ionic liquid
Authors: Zahran Zaki N. , Mohamed Eman A. , Naruta Yoshinori
Published: June 2017

A CaMn-oxide supported on FTO with EMI triflate showed efficient water oxidation at low overpotentials due to the involvement of MnIV species.
Phase separated nanofibrous anion exchange membranes with polycationic side chains
Authors: Abouzari-lotf Ebrahim , Ghassemi Hossein , Nasef Mohamed M. , Ahmad Arshad , Zakeri Masoumeh , Ting Teo M. , Abbasi Ali , Mehdipour-Ataei Shahram
Published: June 2017

Grafting polycationic side chains onto nanofibers results in phase separated membranes with promising alkaline stability and good fuel cell performance.
Boosting the bifunctional electrocatalytic oxygen activities of CoOxnanoarrays with a porous N-doped carbon coating and their application in Zn–air batteries
Authors: Hao Yongchao , Xu Yuqi , Han Nana , Liu Junfeng , Sun Xiaoming
Published: June 2017

A N-doped porous carbon coated cobalt oxide nanoarray electrode was prepared with excellent bifunctional oxygen catalytic performance, and demonstrated good stability and high efficiency in a Zn–air battery.
Mechanochemical design of hemoglobin-functionalised magnetic nanomaterials for energy storage devices
Authors: Rodríguez-Padrón Daily , Puente-Santiago Alain R. , Caballero Alvaro , Benítez Almudena , Balu Alina M. , Romero Antonio A. , Luque Rafael
Published: June 2017

A bionanomaterial based on horse hemoglobin and cobalt oxide magnetic nanoparticles was synthesized using a mechanochemical protocol and further employed in the design of an energy storage device.
New stimulus-responsive shape-memory polyurethanes capable of UV light-triggered deformation, hydrogen bond-mediated fixation, and thermal-induced recovery
Authors: Ban Jianfeng , Mu Luona , Yang Jinghao , Chen Shaojun , Zhuo Haitao
Published: June 2017

This paper presents the development of a novel stimulus-responsive SMP that is capable of shape deformation under UV light and shape fixation in visible light. Finally, the original shape is recovered at higher temperature.
Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma
Authors: Davoodi Pooya , Srinivasan Madapusi P. , Wang Chi-Hwa
Published: June 2017

Using core–shell microparticles encapsulating p53/β-CD-g-CS NPs and nutlin-3a effectively suppressed p53–MDM2 interaction and restored p53 apoptotic activity in cancer cells.
Investigations of a catalyst system regarding the foamability of polyurethanes for reactive inkjet printing
Authors: Schuster Fabian , Ngako Ngamgoue Fabrice , Goetz Tobias , Hirth Thomas , Weber Achim , Bach Monika
Published: June 2017

Polyurethane inks were developed and investigated to manufacture PU-foams via reactive inkjet printing.
Design principles of carbazole/dibenzothiophene derivatives as host material in modern efficient organic light-emitting diodes
Authors: Li Junming , Dong Shou-Cheng , Opitz Andreas , Liao Liang-Sheng , Koch Norbert
Published: June 2017

Host materials for modern high-efficiency organic light-emitting diodes (OLEDs) based on phosphorescence and thermally activated delayed fluorescence were optimized with respect to thermal stability, photophysical properties, energy levels, and charge carrier transport.
Electric field-tunable electronic structures of 2D alkaline-earth metal hydroxide–graphene heterostructures
Authors: Xia Congxin , Gao Qiang , Xiong Wenqi , Du Juan , Zhao Xu , Wang Tianxing , Wei Zhongming , Li Jingbo
Published: June 2017

In X(OH)2/graphene (X = Ca, Mg) vdW heterostructures, the Schottky barrier height and contact types are effectively tuned by electric fields.
Specifics of formation the portfolio of orders on the basis of break even analysis for Iron and Steel Works
Authors: Zambrzhitskaia Evgenia , Kozlova Tatyana , Mamaeva Anastasia
Published: June 2017

The issue of orders portfolio formation becomes more and more actual in terms of evolving economy crisis, consequences of which turned into the growing competition both in domestic and foreign markets. Goals of research – formalization of order portfolio formation procedure. The purpose of our academic research – to develop the algorithm for order portfolio formation suitable for iron and steel works. The article suggests the possibility of using break-even analysis indices, in particular, the research introduces a «break-even point» concept in terms of efficient order portfolio. Usage of break-even point indices is more preferable to others (marginal revenue, cost-effectiveness and etc.) the main advantages of the suggested analysis are: 1) great information capacity from the point of management decision making; 2) the suggested analysis is less governed by price factor than marginal revenue.
Developing methods of controlling quality costs
Authors: Gorbunova A. V. , Maximova O. N. , Ekova V. A.
Published: June 2017

The article examines issues of managing quality costs, problems of applying economic methods of quality control, implementation of progressive methods of quality costs management in enterprises with the view of improving the efficiency of their evaluation and analysis. With the aim of increasing the effectiveness of the cost management mechanism, authors introduce controlling as a tool of deviation analysis from the standpoint of the process approach. A list of processes and corresponding evaluation criteria in the quality management system of enterprises is introduced. Authors also introduce the method of controlling quality costs and propose it for the practical application, which allows them to determine useful and unnecessary costs at the existing operating plant. Implementing the proposed recommendations in the system of cost management at an enterprise will allow to improve productivity of processes operating and reduce wasted expense on the quality of the process on the basis of determining values of useful and useless costs of quality according to criteria of processes functioning in the system of quality management.
Management of mechanical engineering design processes based on product cost estimates
Authors: Kolbachev Evgueniy
Published: June 2017

It is herein conjectured that the cost of a machine can be estimated early in the engineering process. Such estimation is based on an integral index of its informational (parametric) complexity. The index also factors in the properties of materials in use as well as the structural components of machine parts. The author has designed an original approach to the management of design processes, which approach is based on the structural index entropy. The entropy level decreases as the structure is optimized. Using the economic parameters should also help decrease such entropy. The author herein presents the instruments for estimating the parametric complexity of a structure. This index may then be used to calculate the projected costs of the structure.
A mechanism for encouraging active consumers to optimize the operations of power supply systems
Authors: Aizenberg Natalia , Voropai Nicolai , Stashkevich Elena
Published: June 2017

We propose to analyze an interaction of power supply company and consumers as a game in which the retailer’s goal is to maximize its profit, and the consumer’s goal is to maximize its utility. The utility function of each consumer is described proceeding from the form of the loss function of the consumer, and one of our goals in the submitted paper is to find how to describe this load function mathematically. We want to develop an economic mechanism that help the power retailer to find an optimal strategy on the set of possible loads and tariffs. They should satisfy a set of constraints binding these two variables by natural requirements imposed on the values of the consumer utility functions.
The interaction problems between large and small business in modern conditions
Authors: Belyaev Mikhail , Sokolova Svetlana , Karpushova Svetlana
Published: June 2017

The development of market relations, changes of the conditions in the business environment encourage the enterprises to look for new management methods and to improve forms of interaction. In this regard, the identification of the interaction of large and small businesses, as well as the evaluation of their relation development seems important and urgent problem in modern conditions. The purpose of the survey – the study of the interaction of large and small businesses, as well as the evaluation of the relations between them. The study was conducted on the basis of a comprehensive and systematic approach in which methods of comparative, retrospective, statistical, mathematical analysis are used. In accordance with the purpose there are identified the prerequisites for the development of large and small businesses, features and their functioning problems, and the links between them. The most common form of interaction of large and small enterprises were identified - outsourcing, franchising, leasing, subcontracting, venture financing, the establishment of regional cooperation forms of large and small businesses. However, the cooperative processes of large and small business in Russia developed are not enough today.The authors identified factors that impede the growth of Russian production, offered recommendations for the development of large and small businesses, justified the state's role in this process. In addition, they described the mechanism of state support of small business, including organizational, financial, information and consulting components.
Selection of executors for realization of individual tasks of the project
Authors: Asanov Askhat , Myshkina Irina
Published: June 2017

This article deals with the task of selection of executors for the realization of individual tasks of a new project. A short review of approaches to the estimation of personnel based on intellectual methods is provided. Two approaches to the task solution of executors’ selection are reviewed. The first approach allows considering estimation of competence of potential executors and data about projects that have already been realized. These data and requirements to the tasks of new projects are presented with the help of cognitive map with correspondent vertices. In the article, a methodologic example of the suggested approach use is introduced. The second approach suggests the use of Hopfield’s neural network. Neural networks allow using the already available experience of project activities during realization of new projects.
Evaluation of “direct input” effectiveness for industrial enterprises power supply
Authors: Malinina Tatyana , Smolovik Serguei , Ivanov Mikhail
Published: June 2017

The cost of energy has increased significantly for the industrial enterprises over the recent years, due to an increase in the electricity tariffs and the changes in the rules of the electricity market. Tariffs for electricity sold to consumers, differentiated according to various parameters, one of which is the voltage range. The higher the voltage range, the lower the tariffs, and thus, the consumer pays less for the supplied energy. Currently only for big consumers made energy supply “direct input” through the construction of an overhead line (OL) with a nominal voltage of 110 kV or 220 kV. However, it is advisable to consider the issue of power supply efficiency of big and medium-sized industrial enterprises based on the “direct input”. The questions of voltage level study based on empirical formulas are considered in the article, expressing the dependence of the voltage from the transmission distance and the amount of transmitted power. It was proven that these formulas give a large spread, so intermediate voltage classes 35 kV and 110 kV, which compared with the traditional option of power supply on the basis of the cable line 10 kV, have been selected. Based on the technical and economic calculations it has been proved the value of the transmit power and length of the line at which the power supply of industrial enterprise on the basis of “ direct input” with a nominal voltage of 110 kV becomes effective.
The genesis of the Russian mergers and acquisitions market: the role of the industrial sector
Authors: Aleksey Ivanov
Published: June 2017

The article presents the Mergers and Acquisitions quantity and aggregate cost dynamics analysis with the involvement of Russian companies as of from 2001 to 2015. The statistical information on the quantity and volume of M&As in Russia and worldwide was used as an initial benchmark data for the research. The article deduces the conclusion that the dynamics of Russian M&A market development resembles the international one in the whole period up to the year 2014. Starting from 2014 Russian and international M&A markets shows polar trends. This fact connected chiefly to the negative trends in Russian economy due to economic sanctions and weak exportable raw products prices. The article also gives the analysis of Russian M&A market structure from several different perspectives: transactions prices range, capital flow, and integration fields. The main specific features of Russian M&A market are outlined in the light of the reviewed aspects: almost a half of M&A market value is formed through major transactions; internal transaction dominance (sellers and buyers are Russian companies);most of the deals are conducted with involvement of industrial enterprises. The results of this study can be used in forecast development of Russian M&A market trends.
A comprehensive approach to optimization of industrial enterprises management structure
Authors: Salov Aleksey , Gavrilova Anna , Sagitova Lyaisan
Published: June 2017

The conditions of functioning of the power plants management systems are considered in the article. Comprehensive analysis of. The comprehensive analysis of the current and previously used management structures showed a variety of possible options for constructing them. There is proposed a set of partial criteria of the analyzed management structures grouped in local criteria that determine the features of the power plants functioning. Functions of local optimization criteria are identified. The formulated partial and local criteria of the management structures characterize balance, integrity, controllability, and stability of the analyzed control systems and in complex determine the effectiveness of the energy companies. Analysis of the performance of private structures analyzed showed that the assessment of the quality of the particular criteria give different, uncorrelated and conflicting results. It is necessary to develop methods of multi-criteria evaluation to get an unequivocal result of the system effectiveness of the analyzed management structures.
Network technologies as innovative solution in commodity circulation
Authors: Krasyuk I.A. , Kirillova T.V. , Kozlova N.A.
Published: June 2017

The paper identifies the specific features of innovations in the trade industry. Innovations, created in other industries, are preferably used in the area of trade. The types of innovations in the field of trade have been specified. The establishment of a networking commercial enterprise has been defined as an innovative solution, widely used in Russian and world practice. The current state of network trade has been investigated and the tendency of retail network expanding in the Russian Federation has been discovered. The concept of a multi-format establishment and the most perspective trade formats have been identified based on the example trading company X5 RetailGroup.
1C software vulnerabilities description
Authors: Ivanov Oleg , Silnov Dmitry
Published: June 2017

This article is devoted to the vulnerability of the application solution based on the “1C: Enterprise 8” platform, which can be used by only built-in tools of the platform. Possible threats and attack algorithm are described.
The increasing concentration at industrial markets: the social welfare maximization and possible risks
Authors: Filatov Alexander , Makolskaya Yana
Published: June 2017

The paper considers impact of entry barriers on the social welfare. Despite the common opinion that entry barriers are always bad, the excessive number of firms means, all pros aside, duplicated fixed costs. It is shown that the socially effective number of firms is smaller than the equilibrium one for the wide spectre of demand and cost functions, and also for different strategies of companies’ behavior. This proposition is satisfied for the homogeneous product markets where output of each company decreases when the number of firms increases, and competition gets stronger. But there is the considerable danger of the increasing probability of collusion in a situation of number of firms limitation. We show that collusion is less dangerous than duplicated fixed costs if the gap between the «choke price» and marginal costs is less than a certain critical value connected with the share of fixed costs. The empirical research on the base of the financial statistics of the biggest world corporations of different industries is carried out.
Improvement of methods of evaluation of investment projects in the context of import substitution
Authors: Kuvshinov M.S. , Komarova N.S.
Published: June 2017

Due to the imposition of sanctions, based more on geopolitical interests, there were additional essential restrictions on sources of external credits, use of import raw materials and technologies, possibilities of attraction to work of the qualified employees which do not have the Russian nationality, participation in the international technology and scientific projects. At similar restrictions of different resources investment decisions are made extremely carefully, and especially careful and reasonable efficiency evaluation of the investments is required. Traditionally used techniques of efficiency evaluation of investment projects not fully consider strategic interests of owners of industrial enterprises and investors. Decrease in risks requires higher quality of project evaluation. In this work the method of multi-level consistently complex integral assessment of investment projects on an indicator of the integral indicator of their efficiency implementing consecutive selection of investment projects from a portfolio on essential indicators of commercial effectiveness, efficiency of production business activities, a financial state and productivity of activity is provided. The developed method of a complex assessment of investment projects is implemented for practical application by the software product allowing to create on the basis of economic-mathematical modeling specific recommendations in economic practice of industrial enterprises during the developing and implementation of investment strategies. The conclusion that for the Russian economy in the conditions of import substitution accounting of all set of interests of investors and owners of the enterprises provides development and implementation of reasonable investment strategies is drawn.