bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Media Information Literacy vs. Fake News: Probing the Business Decisions under COVID-19 times as Innovation skills with fsQCA
Authors: Mejía-Trejo Juan , Loza-Vega Ismael
Published: March 2023

Purpose. This research aims to probe a framework explaining how the social media user professionals in digital marketing and e-business can use social media information literacy (SMIL) for business decisions under COVID-19 times as innovation skills to combat fake news narratives (FKN) to the next normal.Methodology. A literature review was done with Delphi-Focus Group and Analytic Hierarchy Process (AHP) under academics and professionals' supervision as SMIL experts. The survey was on 400 young Mexican SMEs' digital marketing and e-business from Jul-Sep 2021.Findings and Originality. The original findings confirm a framework with five factors, nineteen variables, 71 items, and five paths as innovation skills.Originality. The fuzzy-set Qualitative Comparative Analysis (fsQCA) technique to discover relationships
The Administrative Power: How State Courts Can Expand Access to Justice
Authors: Monea Nino C.
Published: March 2023

This Article examines the administrative powers of courts and the ways it can be used to expand access to justice. Administrative power, or rule-making power, is the power that state supreme courts have to regulate the lower courts, rules, practice and procedure, and the legal profession. Although they are often underutilized these powers have great potential to address the access to justice crisis throughout the nation. For virtually every area of law is touched by the administrative power of courts. The Article details the extent of the access to justice crisis, charts the history of administrative powers over time, and explores their benefits. It then proposes five solutions that state high courts should implement:(1) making courts more accommodating to self-represented parties,(2) opening up the justice system so that non-lawyers can play more meaningful roles in court,(3) using summary jury trials to reduce the costs of litigation for civil plaintiffs,(4) reforming pro bono so that more lawyers contribute to it, and(5) establishing and expanding funding mechanisms to pay for access to justice initiatives.In the end, the Article seeks not only to convince courts to adopt reforms, but to convince legal reformers that the rule-making powers of courts should be given as much attention as traditional litigation to advance reform.
NOMOFOMO in the health of the Smartphone User for the New Normal: a contribution to the Social Media Health Interaction Theory
Authors: Mejía-Trejo Juan
Published: March 2023

Purpose. The paper is aimed to explain how the NOMOFOMO proposal framework, composed of social media innovations acceptance (SMA), “nomophobia” (NMF), and “fear of missing out” (FOM), interacts with smartphone health user repercussions (HRP), contributing to profile social media health interaction theory (SMT).Methodology. It is based on a literature review defining a final questionnaire survey to 431 smartphones users (Jun-Aug-2021) with PLS-SEM analysis.Results. SMA Socialization and Education dimensions, and HRP like pain and movement extremely slowly appearing face like upset or sad, anxiety and anger as central affections. Originality. The framework gathers four empirically proved separately constructs.
Two and a Half Years Follow of the Pontic Site Development with Root Submergence Technique: A Case Report
Authors: Sah SK
Published: March 2023

A soft tissue drape that is formed around the tooth, as it emerges from the bone, has both aesthetic and functional significance. Post-extraction soft and hard tissue changes are inevitable and it leads to a buccal concavity. The pontics for tooth or implant supported fixed partial denture in such cases appear longer. Preservation of a part of root preserves the periodontal apparatus and hence facilitates the optimal region for the pontic site development. This case report describes root submergence technique for pontic site development in maxillary anterior tooth-supported FPD with a follow up of two and a half years.
Product Innovation and Consumer Preference for Feminine Hygiene Products: A Moderated Model with Product Deprivation
Authors: Gautam Prakash Kumar , Khadka Srijana
Published: March 2023

The study aimed to analyze the impact of product innovation on consumer preferences for feminine hygiene products. The study also investigated the mediated and moderated influence of deprivation on the adoption of the product. Following the analytical research design and deductive approach, the study has been conducted by adopting a multistage sampling method among the females dwelling in Kathmandu, economically active in different sectors, and with active menstrual cycles. The structured questionnaire prepared by adapting validated variables was used to collect the data from 385 respondents working in 50 organizations. Descriptive and inferential analysis was done using Process Macro for mediation and moderation effects using Hayes (2017) models. The study concludes that product innovation significantly impacts consumer preference, with a positive interactive moderation effect of deprivation with product innovation for consumer preference in feminine hygiene product adoption.
Social Media and Purchase Habits of Consumers
Authors: Parajuli Suman Kamal , Budhathoki Dhruba Kumar
Published: March 2023

This research focused on social media’s impact on purchasing decisions in the Lalitpur district. Through the convenience sample, two-hundred responses were obtained through five-point Likert-type questionnaires. Based on descriptive statistics, correlation analysis, and regression analysis, Consumers’ actions were shown to be significantly and positively correlated with the degree to which they trusted content shared on social media platforms. However, perceived risk was found to have a negative and significant relationship with consumer behavior. In addition, the perceived value was found to have a significant positive association with consumer behavior. The regression analysis showed that trust in social media and perceived value significantly affect consumer behavior. At the same time, perceived risk was found to have a significant adverse effect on consumer behavior. This study concluded that the impact of social media has a significant effect on consumer behavior in Lalitpur District.
Relevancy of Revised Bloom's Taxonomy in School-Level English Language Curriculum
Authors: Sapkota Ashok
Published: March 2023

The study is based on the analysis of curriculum objectives of Compulsory English textbooks for grades 6, 9 and 11 based on the educational taxonomy of Bloom and its relevance. It is based on the document analysis of all two-level curriculum analysis: basic and secondary level and the selection of the objectives in relation to the six levels of educational objectives and higher order thinking and lower order thinking skills. Based on the international and national review of secondary sources, the study focuses on the curriculum analysis of the Compulsory English curriculum. It was found that the curriculum objectives were more focused on reading and writing skills compared to listening and speaking skills. With regard to thinking skills, it was found that the majority of the curriculum objectives and its learning outcomes included lower order thinking skills (LOTS) more than higher order thinking skills (HOTS) in grades 6 and 9 more than of grade 11.
Lesson Planning for Language Teaching
Authors: Sharma Bam Dev
Published: March 2023

It is universally accepted that effective teaching is the outcome of an effective lesson plan. It is the signpost of teaching learning activities. Lesson plan becomes a blueprint as it consists of content, methodology, objectives, and process through which measurable and achievable objectives can be obtained. Lesson plan, as a means of technique of teaching, cannot only support teachers; it also provides good feedback and systematic growth in the process of teaching and learning. This article highlights a lesson plan as an instrumental objective of teaching; both innovative and worthwhile for teachers, especially in the field of language teaching. Besides the accompanied sample of lesson plan, can give an outline of how a teacher can make lesson plans interactive to engage students in purposeful teaching learning tasks.
Effect of Training on Job Performance: A Case of Nepalese Civil Servants
Authors: Niraula Ganesh Pd. , Niroula Ballav
Published: March 2023

This research aims to find out the effect of training on the performance of Nepalese civil servants. This research follows a survey research method. It provides a brief analysis and an understanding of the job performance of Nepalese civil servants. The total population of this study is 88657 (65089 males and 23568 females) and 116 samples have been taken for this study. The simple random sampling technique has been applied for the selection of the respondents. The primary data collected through structured questionnaires are analyzed and interpreted using descriptive and inferential statistics. This study's findings revealed on the job performance of civil servants in Nepal. The independent variables (learning, good governance, e-governance and motivation). The dependent variable is the job performance of civil servants. It is revealed that the training has played a crucial role in the job performance of Nepalese civil servants through the utilization of learning, motivation, and good governance and E-governance mechanism. The results show, there is a positive and significant effect of motivation, E-governance, and good governance but learning has a negative and insignificant effect on job performance of Nepalese civil servants.
Literary Representation of Women in South Asian Writings
Authors: Dhobi Saleem
Published: March 2023

This paper scrutinizes the portrayal of women in South Asian fiction by female writers who have been vocal and have been advocating the rights of women in general and the rights and position of Muslim women in particular. How society treats women at different phases of life: daughterhood, womanhood and motherhood have been the point of examination in this article. The paper employs the radical feminist perspective as a theoretical tool to examining the represented position of women in novels of Monica Ali and Taslima Nasreen who belong to Bangladesh but reside beyond the national territory. Ali’s Brick Lane and Nasreen’s My Girlhood have been undertaken as the primary texts to study about the depiction of Muslim women. Women are not inferior to men in any respect. However, through socialization, they are made to feel that they are subordinates to men and their lives are incomplete without the support of men. This feeling instead of capacitating women weakens their will power and ultimately they develop a psyche that men are superior beings and therefore, they must abide by the dictates of men in both personal and professional lives. Both of the novels portray women as daughters, wives and mothers who subordinate men and stay obedient to their counterparts to the extent they are devoid of their existence. When they realize their subjugated position and know the world around, they seek for their individual identity. Despite such portrayals of women’s subjugation and marginalization in patriarchy fueled by doctrines of Islam, some feminist critics including Hosseini assert that the pathetic condition of women in Muslim societies is because of political Islam. Therefore, the generalized view of Islam is questionable.
Mesencephalic developmental venous anomaly causing obstructive hydrocephalus: illustrative case
Authors: Hiraga Kota , Hayashi Shigemasa , Oshima Ryosuke , Kondo Tatsuma , Kanamori Fumiaki , Saito Ryuta
Published: March 2023

BACKGROUND

Developmental venous anomalies (DVAs) are congenital anatomical variants of the normal deep parenchymal veins. DVAs are occasionally found incidentally on brain imaging, and most cases are asymptomatic. However, they rarely cause central nervous disorders. Herein, a case of mesencephalic DVA that caused aqueduct stenosis and hydrocephalus and discuss its diagnosis and treatment is reported.

OBSERVATIONS

The patient was a 48-year-old female who presented with depression. Computed tomography and magnetic resonance imaging (MRI) of the head revealed obstructive hydrocephalus. Contrast-enhanced MRI revealed an abnormally distended linear region with enhancement on the top of the cerebral aqueduct, which was confirmed as a DVA by digital subtraction angiography. An endoscopic third ventriculostomy (ETV) was performed to improve the patient’s symptoms. Intraoperative endoscopic imaging showed obstruction of the cerebral aqueduct by the DVA.

LESSONS

This report describes a rare case of obstructive hydrocephalus caused by DVA. It highlights the usefulness of contrast-enhanced MRI for diagnosing cerebral aqueduct obstructions due to DVAs and the effectiveness of ETV as a treatment option.
Iatrogenic contralateral foraminal stenosis following lumbar spine fusion surgery: illustrative cases
Authors: Konbaz Faisal , Aldakhil Sahar , Alhelal Fahad , Abalkhail Majed , Bourghli Anouar , Ateeq Khawlah , Aleissa Sami
Published: March 2023

BACKGROUND

Lumbar spine fusion is the mainstay treatment for degenerative spine disease. Multiple potential complications of spinal fusion have been found. Acute contralateral radiculopathy postoperatively has been reported in previous literature, with unclear underlying pathology. Few articles reported the incidence of contralateral iatrogenic foraminal stenosis after lumbar fusion surgery. The aim of current article is to explore the possible causes and prevention of this complication.

OBSERVATIONS

The authors present 4 cases in which patients developed acute postoperative contralateral radiculopathy requiring revision surgery. In addition, we present a fourth case in which preventive measures have been applied. The aim of this article was to explore the possible causes and prevention to this complication.

LESSONS

Iatrogenic foraminal stenosis of the lumbar spine is a common complication; preoperative evaluation and middle intervertebral cage positioning are needed to prevent this complication.
Intraoperative air embolism diagnosis and treatment using hyperbaric oxygen therapy after craniotomy: illustrative case
Authors: Malhotra Armaan K. , Chang Ashton P. , Lawton Joseph P. , Alves Aderaldo Costa , Jerath Angela , Tillmann Bourke W. , Foster Harry , Mashari Azad , da Costa Leodante , Kumar Ashish
Published: March 2023

BACKGROUND

This report describes the use of hyperbaric oxygen therapy for the acute management of an intraoperative air embolism encountered during a neurosurgical procedure. Furthermore, the authors highlight the concomitant diagnosis of tension pneumocephalus requiring evacuation prior to hyperbaric therapy.

OBSERVATIONS

A 68-year-old male developed acute ST-segment elevation and hypotension during elective disconnection of a posterior fossa dural arteriovenous fistula. The semi-sitting position had been used to minimize cerebellar retraction, raising the concern for acute air embolism. Intraoperative transesophageal echocardiography was utilized to establish the diagnosis of air embolism. The patient was stabilized on vasopressor therapy, and immediate postoperative computed tomography revealed air bubbles in the left atrium along with tension pneumocephalus. He underwent urgent evacuation for the tension pneumocephalus followed by hyperbaric oxygen therapy to manage the hemodynamically significant air embolism. The patient was eventually extubated and went on to fully recover; a delayed angiogram revealed complete cure of the dural arteriovenous fistula.

LESSONS

Hyperbaric oxygen therapy should be considered for an intracardiac air embolism resulting in hemodynamic instability. In the postoperative neurosurgical setting, care should be taken to exclude pneumocephalus requiring operative intervention prior to hyperbaric therapy. A multidisciplinary management approach facilitated expeditious diagnosis and management for the patient.
Od katolicyzmu do katolickości. W poszukiwaniu adekwatnej eklezjologii dialogicznej
Authors: Nadbrzeżny Antoni
Published: March 2023

Celem artykułu jest ukazanie znaczenia, sensu i potrzeby nowego typu myślenia o Kościele, które zostało określone mianem „eklezjologii dialogicznej”. Stanowi ona odpowiedź na wezwanie Soboru Watykańskiego II do budowania relacji między Kościołem i światem współczesnym opartej na kategorii dialogu. Zawarte w tytule sformułowanie „od katolicyzmu do katolickości” sugeruje konieczność odejścia od defensywnej wizji Eklezji (określanej mianem katolicyzmu) na rzecz afirmacji otwartej i dialogicznie rozumianej katolickości Kościoła. Wypracowanie adekwatnej, spójnej i wiarygodnej eklezjologii dialogicznej wymaga głębszego przemyślenia znaczenia dialogicznej istoty Kościoła, precyzyjnego określenia adresatów, płaszczyzn i celów eklezjalnego dialogu ad extra. Artykuł, ukazując Kościół jako dialogiczny sakrament zbawienia w historii, łączy perspektywę teologiczną (dogmatyczną) z egzystencjalną, uwzględnia wrażliwość współczesnych ludzi na trudny do akceptacji fenomen cierpienia, który z racji swego uniwersalizmu może jednak stanowić płaszczyznę twórczego spotkania ludzi wierzących z ateistami/agnostykami. W swym teologicznym przekazie artykuł jest wyrazem chrześcijańskiej nadziei, objawiającej swą siłę również we współczesnej, zsekularyzowanej „kulturze tymczasowości”. Ukazuje wartość autentycznego spotkania ludzi reprezentujących różne religie i światopoglądy, którzy w ramach uczciwie prowadzonego dialogu mogą odkryć głębszy sens swojej wiary, egzystencji i współpracy w obronie zagrożonego człowieczeństwa, obiektywnie stanowiącego imago Dei.
Comparative Characterisation Study of the Properties of Modified and Unmodified African Locust Beans (Parkia Bigbosa) Marketed in Ilisan/ Shagamu Area of Ogun State, Nigeria
Authors: Digbo I Idika , Vera C Anaekwe , Nelly A Ndukwe
Published: March 2023

Introduction: Parkia biglobosa is a wide leguminous plant found in Nigeria and many other African countries. It has been found to contain high calorific value, essential proteins, fatty acids etc. Aims and Objectives: The aim and objective of this work amongst others is to characterize the modified and the unmodified African locust bean with the view of finding out their nutritional value. Methodology: Scanning electron microscopy (SEM) was carried out on both the unmodified and modified samples at different magnifications in order to determine their morphologies. Also, Fourier transformed Infrared spectroscopy (FT- IR) was employed to investigate the functional groups and their intensities in the water-based extract of both samples. Finally, X-RD analysis was carried out on the unmodified water-based extract in order to determine the phase names available in the sample. Results: From the SEM analysis, patches and pores were found in each of the samples, but the patches on the modified sample appeared wider than the ones seen in the modified sample. This could be as a result of the breakdown of proteins by microorganisms in the course of fermentation. The following functional groups were detected in the unmodified water sample with their intensities: O-H, N-H (45.64) CH2 O asymmetric, C-H stretch (85.55), CH2 O symmetric, C-H stretch (91.04), C≡N, C≡C (95.16), C=O (64.14) C-CH asymmetric bend (85.22), SO2 symmetric stretch sulfate (85.43) and C-N Stretch (85.42). Additionally, the following functional groups with their intensities were recorded for the modified water based extract: O-H, N-H (74.75), C-N (82.30), C≡N, C≡C (96.34), C=O (85.07), CO2 asymmetric stretch (67.44), CH3 umbrella (74.78), Alkyl/Aryl (83.72), SO2 stretch sulfate (81.73) amongst other vital result obtained from X-RD analysis. Conclusion: More functional groups were prevalent in the modified African locust beans seeds than in the unmodified including their intensities. This is indicative of more nutritional value in the modified sample compared with the unmodified sample.
The «Armenian» Canons of Council in Trullo
Authors: Казарян Г.С.
Published: March 2023

Статья посвящена исследованию группы священных правил, изданных Пято-Шестым или Трулльским Cобором (Константинополь, 691-692 гг.) относительно «страны Армянской». На основе анализа первоисточников, во-первых, выявляется исторический контекст публикации этих правил: отцы Трулльского Собора попытались регулировать церковную жизнь Армении, поскольку её Церковь официально придерживалась церковного единства, заключенного на Каринском (Феодосиопольском) Соборе в 632/3 г., несмотря на то, что внутри Армянской Церкви фактически существовали две партии - халкидонитская и антихалкидонитская. Далее в статье предпринята попытка рассмотрения правил по отдельности. В свете новых исследований по литургике прослеживается историко-богословское развитие тех или иных обрядовых явлений, относительно которых были изданы правила. Изучение данных обрядовых особенностей армянского типикона под призмой диахронического подхода в свою очередь позволяет выявить актуальность «армянских» правил Пято-Шестого Вселенского Собора для наших дней.

The article is dedicated to the study of the group of sacred rules issued by the Quinisext or Council in Trullo (Constantinople, 691-692) concerning «the country of Armenians». On the basis of an analysis of the original sources, rst of all, the historical context of the publication of these rules is revealed: the Fathers of the Council tried to regulate the ecclesiastical life of Armenia, as its Church of cially adhered to the ecclesiastical unity achieved at Council of Karin (Theodosiopolis) in 632/3, despite the fact that there were actually two parties within the Armenian Church, the Chalcedonian and the Antichalcedonian. Then the article attempts to investigate the rules separately. In the light of new researches on liturgics, we examine the historical and theological development of ritual phenomena on which regulations have been issued. The study of these ritual speci ties of the Armenian typicon under the prism of the diachronic approach in its turn allows us to reveal the relevance of «Armenian» rules of the Quinisext Ecumenical Council for today.
Is Consciousness Gendered?
Authors: Chappell Sophie-Grace
Published: March 2023

We can ask whether there anything it is distinctively like to be female or male (a question about sex). And we can ask whether there anything it is distinctively like to be feminine or masculine (a question about gender). I think the answer to both these questions is “Obviously yes”. Why yes? And why obviously? Consciousness is gendered, and obviously gendered, because the political realities of what it is like to be masculine, and what it is like to be feminine, are distinctively different. Moreover, consciousness is sexed too, and obviously sexed, because the physical realities of what it is like to be male, and what it is like to be female, are distinctively different. And that is why the answer to our two questions is not just “Yes”, but “Obviously yes”.
Determining destination competitiveness in medical tourism: A study based on AHP-QFD framework
Authors: YİLMAZ Vildan , GÜNEREN Ebru
Published: March 2023

This study investigates the competitiveness of Alanya, a medical tourism destination in Türkiye, and determines appropriate strategies using the analytical hierarchy process and quality function deployment. Data were collected from medical tourism experts to gain managerial insights into the factors affecting the competitiveness of medical tourism. The findings show that medical tourists primarily focus on medical factors such as competence of doctor and quality of treatment. The main strategies to strengthen competitiveness are to create a healthcare-free zone, to increase the number of accredited health care providers, and to encourage the involvement of doctors in academic research and ongoing training. For researchers interested in assessing competitiveness in medical tourism destinations, the study presents general determinants that should be considered in each destination. In addition, the findings show that each medical tourism destination should focus on its own determinants of medical tourism competitiveness when developing its marketing strategies. Finally, it shows that the analytical hierarchy process and quality function deployment approaches can be successfully applied in achieving destination competitiveness and strategic planning, with content validity and importance performance analysis.
Samoborski
korijeni lingvista i hrvatskog preporoditelja Vjekoslava
(Alojzija) Babukića, iz Agate Kelleković izhadjajućega odvetka
Authors: Brekalo Ivanka
Published: March 2023

Tekst je prilog biografiji lingvista i hrvatskog preporoditelja Vjekoslava (Alojzija) Babukića - u povodu 210. godišnjice rođenja (Požega, 1812.). Na temelju arhivske građe Samoborskoga muzeja, tekstom se dopunjuju podaci o podrijetlu njegove majke te iznosi dokument u kome je u okviru provođenja ostavinske rasprave i sam Babukić, diktirajući i potpisujući, dao opsežniji iskaz na samoborskoj kajkavštini. Potvrđuje se Babukićeva povezanost sa Samoborom.
Condensation of secondary amines with CH-acids and formaldehyde under the influence of microwave radiation
Authors: Musin A. I. , Sultanova D. S. , Borisova Yu. G. , Mudrik T. P. , Daminev R. R.
Published: March 2023

Objectives. To synthesize tertiary amines containing gem-dichlorocyclopropane or 1,3-dioxolane fragmentusing the Mannich reaction, as well as obtain ethyl ester of β-aminopropionic acidbydecarboxylation of tert-amine, a derivative of diethylmalonate containing a gem- dichlorocyclopropane fragment.Methods. In order to obtain tertiary amines by the Mannich reaction, the microwave activation method was used. To determine the qualitative and quantitative composition of the reaction masses, gas chromatography, electron ionization mass spectrometry, and 1H-, 13C-nuclear magnetic resonance spectrometry methodswere used.Results. Under microwave radiationconditions, tertiary amines containing gem- dichlorocyclopropane or 1,3-dioxolane fragment were synthesized by condensation of secondary amines, CH-acids, and paraformaldehyde.Conclusions. Tertiary amines containing a gem-dichlorocyclopropane or cycloacetal fragment in their structure were obtainedin high yields under microwave radiation.
Combined process of cyclohexyl cyclohexanecarboxylate synthesis from cyclohexanol and CO catalyzed by the Pd(OAc)2–PPh3–p-toluenesulfonic acid system
Authors: Sevostyanova N. T. , Batashev S. A. , Rodionova A. S.
Published: March 2023

Objectives. To study the possibility of combining acid-catalytic cyclohexanol dehydration and alkoxycarbonylation of the formed cyclohexene with cyclohexanol and carbon(II) oxide in a single reactor in order to achieve high yields of the target cyclohexyl cyclohexanecarboxylate product under mild conditions using the Pd(OAc)2–PPh3–p-toluenesulfonic acid catalytic system.Methods. The combined process took place in a toluene medium in a periodic steel reactor designed to operate at elevated pressure, equipped with a glass insert, a magnetic stirrer, and a sampler, as well as gas input and discharge devices. The reaction mass with the components of the catalytic system was placed in a glass reactor inside a steel autoclave. The reaction mass samples obtained during the combined process were analyzed by gas–liquid chromatography with a flame ionization detector.Results. The possibility of combining cyclohexanol dehydration catalyzed by p-toluenesulfonic acid monohydrate and formed cyclohexene alkoxycarbonylation with cyclohexanol and CO during catalysis by the Pd(OAc)2–PPh3–p-toluenesulfonic acid system in a single reactor was demonstrated. Under mild conditions (temperature 110°C; CO pressure 2.1 MPa), the target product yield reached 64.8% in 5 h. However, the combined process is complicated by the formation of a cyclohexanecarboxylic acid by-product formed as a result of the cyclohexyl cyclohexanecarboxylate hydrolysis and the cyclohexene hydroxycarbonylation.

Conclusions. The reactions of intramolecular acid-catalytic cyclohexanol dehydration and formed cyclohexene alkoxycarbonylation catalyzed by the Pd(OAc)2–PPh3–p-toluenesulfonic acid system can be combined in a single reactor. p-Toluenesulfonic acid can simultaneously act as a catalyst for the cyclohexanol dehydration and a co-catalyst of the palladium–phosphine system of cyclohexene alkoxycarbonylation. The involvement of cyclohexene, representing a product of reversible cyclohexanol dehydration, in the alkoxycarbonylation reaction is a factor in shifting the dehydration reaction equilibrium towards the formation of cyclohexene. Cyclohexanecarboxylic acid is a by-product of the proposed combined process. A factor in the reduction of target product yield is water formed as a result of cyclohexanol dehydration due to the involvement of the latter in the hydrolysis reaction and the course of the cyclohexene hydroxycarbonylation.
Method for obtaining recombinant antibodies produced by a cell line transduced with recombinant adenoviruses
Authors: Sedova E. S. , Shcherbinin D. N. , Bandelyuk A. S. , Verkhovskaya L. V. , Viskova N. Yu. , Avdonina E. D. , Prokofiev V. V. , Ryabova E. I. , Esmagambetov I. B. , Pervoykina K. A. , Bogacheva E. A. , Lysenko A. A. , Shmarov M. M.
Published: March 2023

Objectives. To develop a technology for obtaining recombinant antibodies in a suspension culture of human HEK293 cells using transduction with recombinant adenovirus serotype 5 (rAd5) carrying genes expressing heavy and light chains of antibodies on the example of two broadspectrum anti-influenza antibodies 27F3 and CR9114.Methods. Ad5-27F3-H, Ad5-CR9114-H, and Ad5-27F3-L recombinant adenoviruses carrying the 27F3 antibody heavy chain gene, CR9114 antibody heavy chain gene, and 27F3 light chain gene, respectively, were generated using the AdEasy™ Adenoviral vector system. To accumulate preparative amounts of recombinant r27F3 and rCR9114 antibodies, the HEK293 suspension cell line was transduced with recombinant adenoviruses carrying genes for heavy and light chains of antibodies. The cells were cultured in a wave-type bioreactor. Chromatography was used to purify recombinant antibodies from the culture medium. After analyzing the molecular weights of purified antibodies using protein electrophoresis, their ability to interact with influenza A and B viruses was analyzed using the Western blot technique, while their ability to neutralize influenza A and B viruses was evaluated using the virus neutralization assay.Results. A method for the accumulation and purification of recombinant r27F3 and CR9114 antibodies from the culture medium of a suspension culture of human cells following transduction with its recombinant adenoviruses carrying the genes for heavy and light chains of these antibodies was developed. The ability of the r27F3 antibody to interact with and neutralize influenza A viruses of group 1 (except influenza A virus subtype H2) and group 2 was shown. The ability of the rCR9114 antibody to interact with influenza A viruses of group 1 and influenza B viruses, as well as to neutralize influenza A viruses of group 1, was demonstrated.Conclusions. A technology for obtaining recombinant antibodies in a suspension culture of HEK293 cells using transduction with recombinant adenoviruses carrying genes expressing heavy and light chains of antibodies was developed along with a confirmation of their specificity.
The teaching of Apostle Peter and Relevance to The Christian Religious Education in Bantul Regency and Gunung Kidul Regency Yogyakarta
Authors: Parulian Tamba , Daliman Muner , Sugiarto Kristian H. , Purwoko Sentot Paul
Published: March 2023

God's chosen people are people who have been redeemed by God Himself through the death of the Lord Jesus Christ on the cross by shedding His blood so that His chosen people can live holy, obedient and pleasing to Him. Thus God's chosen people reveal the face of God Himself. God's chosen people are a light to this dark world. God's chosen people are chosen by God to have fellowship with Him. This is a glorious gift of God where the created can approach its Great and Glorious Creator. In this study, the method used is quantitative with a survey method through a questionnaire. The results showed that throughout his epistle, Peter lays out what it means to be God’ s chosen who proclaim Jesus’ excellencies by way of several exhortations. Accordingly, Peter encourages the new covenant church to live in holiness like redemption accomplished for them in the death and resurrection of Jesus (1 Pet 1:3, 18–19). It is because of their new birth that they are to abstain from a sinful life, and instead long for a grace-filled, wisdom-like life (1 Pet 2:1–3).
The Perspective of Christian Religious Student/Teacher in Kasongan, Central Kalimantan Towards the Concentration of Dialogue: A Study of Paulo Freire
Authors: Mariani Evi
Published: March 2023

The purpose of this study is to explore the perspectives of teachers and students regarding opinions in the dialogue between teachers and students in three high schools in Kasongan. The main question is how students' and teachers' reactions to the teaching and learning process in and out of the classroom are affected the research method uses qualitative research with interview techniques to raise voices (narratives) that are not heard. The results of the verbatim transcript are then processed into factual statements, categories, and themes. Based on this theme, the author analyzes Paulo Freire's philosophy regarding conscientization (there are psychological conditions, namely low self-esteem and fear; social construction) in dialogue. The research subjects were representatives of students and teachers from three public and private high schools. According to a search of teachers at three high schools in Kasongan, dialogue is a consistent egalitarian trail that teachers lay for students, even though there are dual roles as teachers both inside and outside the classroom under certain conditions. However, the perspective of students is that the teacher is a person who is obeyed, thus bringing students into the network and lowering their self-esteem when having a dialogue with the teacher. Nevertheless, dialogue is still possible as long as the teacher positions himself as a traveling partner, so that dialogue is able to run in and out of the classroom.
Road Safety Perceptions and Practices among Undergraduate Medical Students
Authors: Valluri Vandana , Pidakala Mary Moses , Kumar Singh Nihal
Published: March 2023

BACKGROUND The global epidemic of road traffic injuries is on the rise in most regions of the world, ranking as the 8th leading cause of death globally, and bringing about 1.35 million deaths every year, most which are among the 5-29 years age group. Researchers across the globe have identified a glaring gap between the knowledge and the practices of road safety among young adults, with focus on students with commute as a part of their daily routine. OBJECTIVES 1. To assess the knowledge, attitudes and practices of undergraduate medical students towards road safety. 2. To evaluate the factors associated with exposure to RTAs among undergraduate medical students. MATERIALS AND METHODS This was a cross-sectional study was conducted among a purposive sample of 525 undergraduate medical students, studying from first year to final year MBBS, at EISC Medical College, Sanathnagar. Data was obtained on the sociodemographic profiles as we as the knowledge, attitudes and practices of these students towards road safety using an online pre-tested semi-structured questionnaire. RESULTS Mean age of the respondents was 20.7 + 4.5 years, about 60% were females, and majority were studying 2nd year MBBS. Of the 63% respondents that drive vehicles, 80% possess a valid driving license. More than 7% did not consider owning a valid driving license as necessary and only 23.6% were aware of the penalty charged for driving without license. About 12% reported the use of mobile phones while driving. Harmful practices such as driving without parents’ knowledge, jumping the red signal and history of being held by traffic police were all significantly higher among males (p=0.003, 0.000, and 0.000 respectively). CONCLUSIONS There is an alarming degree of risky practices among the undergraduate medicals students, especially males. Their knowledge and perceptions of road safety did not adequately translate into practices.
Választási bűncselekmények a hatályos szabályozás tükrében
Authors: Balázs Bettina
Published: March 2023

A választási bűncselekmények a választási csalásoknál szűkebb tárgykört ölelnek fel, azokat a választási visszaéléseket foglalják magukban, amelyek olyan mértékben sértik a demokratikus választások követelményét, a választások tisztaságát, hogy a Büntető törvénykönyv az elkövetésük esetén büntetés kiszabását rendeli. Jelen tanulmány a választás rendje elleni bűncselekmények, valamint a választásokhoz köthetően elkövethető más bűncselekmények hatályos szabályozását vizsgálja, rámutatva a módosítást igénylő gyenge pontokra.
A választási szervek online ülésezésének megoldásai és kihívásai
Authors: Kurunczi Gábor , Téglási András
Published: March 2023

2020 tavaszán a koronavírus okozta világjárvány az élet minden területén éreztette hatását. A személyes kontaktusok csökkentésének igénye hatalmas kihívás elé állította azon alkotmányos szervek működését is, amelyek testületi szervként látják el feladatukat. Így például a különböző parlamentek vagy épp a magyar Alkotmánybíróság Teljes Ülésének is alkalmazkodnia kellett az online tér kihívásaihoz. Eme probléma alól pedig a választási szervek, különösen a választási bizottságok (mint testületi szervek) működése sem jelent kivételt. Egy választási szerv – különösen, ha jogorvoslati funkciót lát el – egy demokratikus államban különösen nagy jelentőséggel bír. Nem lehet ezért megkerülni, hogy működésük olyan időszakban is garantált legyen, amikor a kontaktusok csökkentése miatt a személyes jelenlét nem, vagy csak nehezen biztosítható. Ezzel együtt pedig a világjárványtól függetlenül is fontos, hogy a 21. században a normál működési rendben is garantálható legyen az online ülésezés, hiszen ez is a választási jogorvoslatban érvényesülő rövid határidők megtartását szolgálná. Ezért fontos szabályozni és kialakítani az online ülésezés lehetőségét, az ilyen eljárást pedig megfelelő alkotmányos garanciákkal kell övezni. Tanulmányunkban ezért áttekintjük a különböző (elsősorban európai) országok választási szerveinek ülésezési eljárását – különös tekintettel a nyilvánosság biztosításának kérdésére – és módját (mennyiben tudnak online formában működni, milyen eljárási keretek között teszik azt), valamint azok normatív szabályait. Emellett közelebbről megvizsgáljuk a magyar választási szerveknek, különösen a Nemzeti Választási Bizottságnak a gyakorlatát és eljárási metódusát is.
Gezilecek Yerlerin Tanıtımında Sosyal Medya Fenomenlerinin Rolü
Authors: MUTLU BAYIN Dilek , AKOĞLAN KOZAK Meryem
Published: March 2023

Bu araştırmanın amacı günümüzün kanaat önderleri sayılabilecek sosyal medya fenomenlerinin gezilecek yerlerin tanıtımındaki rolünü ortaya koymaktır. Araştırma, 1,4 milyon takipçi sayısı ile ünlüler kategorisinde yer alan gezilecek yerler hakkında içerik paylaşımlarında bulunan bugünnereyegidelim hesabı üzerinden yapılmıştır. Seçilen bu hesap, 2021 yılındaki en fazla beğeni ve yorum yapılmış olan seyahat paylaşımlarına sahiptir. Belirlenmiş olan bu hesabın 2021 yılındaki en fazla beğeni ve yorum yapılmış olan seyahat paylaşımındaki yorumlara araştırma soruları kapsamında içerik analizi uygulanmıştır. Analiz sonucunda sosyal medya kanaat önderlerinin rolüne ilişkin beş tanımlayıcı ana temaya ulaşılmıştır. Yorumlamalar bu temalar bağlamında ve katılımcı ifadelerinden oluşan doğrudan alıntılara yer verilerek sunulmuştur. Araştırmanın sonuçlarına göre kanaat önderinin takipçileri üzerinde gezilecek yerler hakkında bilgilendirme, destinasyonu keşfetme, beğenme ve merak etme bağlamında rolleri vardır. Yabancı takipçilere ise Türkiye’nin tanıtımı yapılmaktadır. Sosyal medya fenomenlerinin takipçi sayısı, deneyimli olması ve alanında uzman olması onların güvenilir olduğunu göstermektedir. Ayrıca, sosyal medya fenomenleri, destinasyonu tekrar ziyaret etme, gelecekte oraya taşınma isteği yaratma ve tatil planlarında değişiklikler yapma isteği de uyandırmaktadır.
Gastronomi Turlarında Memnuniyet Yaratan Unsurlar
Authors: BAYRAM Ümmühan
Published: March 2023

Gastronomik unsurlar destinasyonların tercih edilmesini ve destinasyona bağlılığı etkileme gücüne sahiptir. Gastronomi turizmi ise yerel mutfakların gastronomik kimliğini canlandırmakta ve seyahat edenlere yemek tarihi, geleneksel yemek tarifleri, yemek görgü kuralları ile bağlantılı otantik bir kültürel deneyim sunmaktadır. Bu deneyimi edinmek isteyenlerin sayısı ise sürekli artmakta ve gastronomi turlarına ilgi çoğalmaktadır. Bu nedenle araştırmanın amacı gastronomi turlarından memnun kalan tüketicilerin deneyimlerinin incelenmesiyle memnuniyetlerini oluşturan unsurların ortaya çıkarılmasıdır. Bu amaca yönelik olarak araştırmanın verilerini TripAdvisor seyahat uygulamasındaki 2022 yılında ilan edilen en iyiler kategorisinde yer alan en yüksek puanlı gastronomi turlarına ait çevrimiçi konuk değerlendirmeleri oluşturmaktadır. Bu bağlamda araştırmanın veri toplama yöntemi doküman incelemesi ve verilerin analizinde de içerik analizi kullanılmıştır. Gastronomi turlarında memnuniyeti etkileyen unsurlar olarak yiyecek ve içecekler, rehber ve tur hizmetleri ana temaları altında oluştuğu görülmektedir. Ayrıca araştırmanın sonunda gastronomi turlarının organizasyonuna ve bu turlardaki rehberlik hizmetlerine ilişkin önerilerde bulunulmuştur.
Doğal Alanları Ziyaret Edenlerin Duygusal Deneyimleri ile Davranışsal Niyetleri Arasındaki İlişki
Authors: KARA Mikail , TOKMAK Cüneyt
Published: March 2023

Ziyaretçi deneyimi, alan yöneticilerinin başarısı için kritik öneme sahip kavramlardan bir tanesidir. Bu araştırmada ziyaretçi deneyiminin önemli bir parçası olan duygusal müşteri deneyiminin davranışsal niyetle olan ilişkilerinin incelenmesi amaçlanmıştır. Araştırma Çankırı Ilgaz Kadınçayırı Yıldıztepe Kültür ve Turizm Koruma ve Geliştirme Bölgesi’nde (ÇIKY-KTKGB) gerçekleştirilmiştir. Toplamda 437 ziyaretçiden anket yolu ile veriler toplanmıştır. Analiz sonuçlarına göre, ziyaretçilerin duygusal deneyim düzeylerini ve davranışsal niyetlerini ortaya koyan ifadelere yüksek düzeyde katıldıkları görülmüştür. Ziyaretçilerin duygusal deneyimleri ile davranışsal niyetleri arasında pozitif yönlü yüksek bir ilişki olduğu tespit edilmiştir. Duygusal deneyimin davranışsal niyet üzerinde de olumlu bir etkisinin olduğu ortaya çıkmıştır.
Metode Klasifikasi Gejala Penyakit Coronavirus Disease 19 (COVID-19) Menggunakan Algoritma Neural Network
Authors: Rahmi Rahmi , Antoni Darius , Syaputra Hadi , Fatoni Fatoni , Kurniawan Tri Basuki
Published: March 2023

Coronavirus Disease 19 (COVID-19) adalah virus baru yang dapat menyebabkan infeksi saluran pernafasan. Virus ini  berasal dari hewan yang dapat menular ke manusia melalui percikan ludahnya. Menurt data epidemiologis, rata-rata penderita virus ini berusia 15-80 tahun. Virus ini memiliki masa inkubasi 3-14 hari yang memiliki gejala awal yaitu demam tinggi, sesak napas, batuk dan pilek. Indonesia mwmiliki 2 kasus pertama pada 2 Maret 2020, Covid-19 meningkat secara teratur pada 29 Desember 2020 data menunjukkan 719.219 ribu orang dipastikan terjangkit Covid-19. Masalah yang diangkat dalam penelitian ini adalah bagaimana mengklasifikasikan risiko tertular virus Covid-19 dari gejala yang ditimbulkan. Tujuan dari penelitian ini adalah untuk mengetahui nilai akurasi dari klasifikasi resiko tertular virus Covid-19 berdasarkan instrument yang digunkan dari metode Cross Industry Standard Process for Data Mining (CRISP-DM). Dataset yang digunakan peniliti diambil dari website http://github.com/nshomron/covidpred. Penelitian ini menggunakan Algoritma Neural Network (NN) dengan bantuan alat Phyton, akurasi Algoritma Neural Ntwork (NN) diperoleh nilai sebesar 95%, artinya telah menunjukkan hasil klasifikasi yang baik. Peneliti juga menguji dengan Algoritma Logistic Regression namun nilai akurasi yang diperoleh tidak jauh berbeda dengan Algoritma NN, Algoritma Logistic Regression diperoleh akurasi nilai sebesar 94%.
Penerapan Algoritma K-Means Untuk Mengklasifikasi Data Obat
Authors: Ferdy Pangestu Ferdy Pangestu , Nur Yasin Nur Yasin , Ronald Chistover Hasugian Ronald Chistover , Yunita Yunita
Published: March 2023

Pengklasifikasian data obat pada sebuah instansi yang bergerak pada bidang Kesehatan merupakan hal yang sangat penting. Kegiatan tersebut tidak lepas dari pengawasan serta monitoring setiap harinya karena pengolahan data obat termasuk inti dalam berjalannya roda bisnis pada suatu instansi atau perusahaan. Penelitian ini dilakukan untuk membahas pentingnya pengolahan data dalam suatu instansi atau perusahaan yaitu pada Puskesmas Kecamatan Sawah Besar. Saat ini permasalahan yang terjadi adalah tidak adanya suatu metode dalam pengkasifikasian data obat. Obat obatan belum dikelompokkan sesuai dengan karakteristiknya sehingga menjadi kendala saat pencarian data serta saat pengecekan stok. Dengan masalah diatas dibutuhkan suatu metode.  Salah satu dengan menggunakan metode algoritma K-means. K-means clustering merupakan salah satu metode cluster analysis non hirarki yang berusaha untuk mempartisi objek yang ada kedalam satu atau lebih cluster berdasarkan karakteristiknya data-data obat ini diklasfikasikan menjadi 4 kategori yaitu obat bebas, obat bebas terbatas, obat keras, dan narkotika psikotropika. Hasil penelitian yang sudah dilakukan bahwa dengan menggunakan algoritma K-Means pihak Puskesmas Kecamatan Sawah Besar dapat menggelompokkan data obat yang tingkat pemakaiannya tinggi, sedang hingga terendah berdasarkan volume pemakaian dan pemasukan. Data yang diambil dari Puskesmas Kecamatan Sawah Besar merupakan data stok obat pada bulan Desember 2021. Perhitungan manual mendapatkan akurasi yaitu 66,23% untuk cluster 1, 7,69% untuk cluster 2, dan 23,07% untuk cluster 3 pada data obat bebas terbatas.
Penerapan Metode TOPSIS untuk Menentukan Kelayakan Perpustakaan Sekolah Diakreditasi
Authors: Sukamto Sukamto , Id Ibnu Daqiqil , Jukris Avisha Delinda
Published: March 2023

School libraries should be accredited with the aim of improving the quality of libraries. Pekanbaru City Library and Archives Service (DISPUSIP) in determining a school library that deserves to be accredited is still done manually, namely DISPUSIP went directly to the field to monitoring the library in the school and the data collection still used manual entries. Meanwhile, a lot of data must be collected, causing the data to be inaccurate and take a long time. For this reason, a decision support system (DSS) is needed. The data used are nine junior high schools both public and private as an alternative. While the criteria refer to the school library accreditation instrument issued by the National Library (Perpusnas) consisting of six criteria, namely collections, library facilities and infrastructure, library services, library staff, library administration and management, and reinforcement. Data analysis using the TOPSIS method by steps of determining the decision matrix, normalization matrix, calculating both positive and negative ideal solutions, calculating the distance to the ideal solution, calculating preference values, and ranking. The results obtained for the SMP library are Sek 4, Sek 1 and Sek 5 which are eligible for accreditation.