bluuebunny/crossref_metadata_2025 huggingface dataset:
The Economics of Long-Term Care
Authors: Yuen Peter P.
Published: September 2018

This chapter presents key concepts of economics relevant to the financing and delivery of long term care services. It first examines the magnitude of population aging in developed economies, and the associated implications for long term care. Key economic concepts relating to the demand, supply and financing of long term care services are then discussed. Policies, practices and major models of financing of long term care are further explored followed by a presentation of the conceptual framework for reform. It concludes that in view of the magnitude of the problem, incremental changes in the existing systems are unlikely to be adequate. A clear understanding of the economic concepts to underpin major transformation of existing systems and policies that do not align with populations trends is urgently needed.
The Origins of Music and of Tonal Languages
Authors: Ehle Robert C.
Published: September 2018

This chapter offers the author's theory of the origins of music in ancient primates a million years ago, and what music would have sounded like. Origins of nasal and tone languages and the anatomy of larynx is discussed, and then a hypothesis is presented that these creatures would fashioned a tone language. They had absolute pitch that allowed them to recognize other voices, to read each other's emotions from the sounds they made with their voices, and to convey over long distances specific information about strategies, meeting places, etc. Having an acute sense of pitch, they would have sung, essentially using tonal language for aesthetic and subjective purposes. Thus, they would have invented music. Then the physicality of the human (or hominid) voice is discussed and the way an absolute pitch can be acquired, as the musicality still lies in the vocalisms it expresses. The reason for this is that music is actually contained in the way the brain works, and the ear and the voice are parts of this system. The final part discusses the origins of musical emotion as the case for imprinting in the perinatal period.
Kinect Applications in Healthcare
Authors: Lun Roanna , Zhao Wenbing
Published: September 2018

Microsoft Kinect is one of the most popular inexpensive gadgets released in recent years. Kinect is equipped with a color camera, a depth camera, and a microphone array. The device allows users to interact with a computer via a natural user interface in terms of gestures or voice commands. The authors believe that the research and development on using Kinect technology in healthcare will gain more momentum. The demand of Kinect-based applications is high, due to Kinect's low cost and portability, and its accurate and robust motion detection capability. In this chapter, the authors survey the current applications of using the Kinect technology in healthcare. Furthermore, they outline a number of open research issues that could overcome the limitations of the current Kinect technology.
A Validation Study of Rehabilitation Exercise Monitoring Using Kinect
Authors: Zhao Wenbing , Espy Deborah D. , Reinthal Ann
Published: September 2018

In this chapter, the authors present their work on a validation study of using Microsoft Kinect to monitor rehabilitation exercises. Differing from other validation efforts, the authors focus on a system-level assessment instead of the joint-level comparison with reference motion capture systems. They assess the feasibility of using Kinect by examining the enforceability of a set of correctness rules defined for each exercise, which are invariances of each exercise and hence independent from the coordinate system used. This method is more advantageous in that (1) it does not require coordinate system transformation between those of the reference motion capture system and of the Kinect-based system, (2) it does not require an exact match of the Kinect joints and the corresponding external marker placements or derived joint centers often used in reference motion capture systems, and (3) the correctness rules and their mapping for Kinect motion data analysis developed in this study are readily implementable for a real motion monitoring system for physical therapy.
Forensic Investigations in Cloud Computing
Authors: Barrett Diane
Published: September 2018

Cloud computing environments add an inherent layer of complication to a digital forensic investigation. The content of this chapter explores current forensic acquisition processes, why current processes need to be modified for cloud investigations, and how new methods can help in an investigation. A section will be included that provides recommendations for more accurate evidence acquisition in investigations. A final section will include recommendations for additional areas of research in the area of investigating cloud computing environments and acquiring cloud computing-based evidence.
A Sociological Study of the Role of Language in Education
Authors: Saeed Naima , Rehman Tansif Ur , Usmani Mehmood Ahmed
Published: September 2018

The present article is on the role of language in education. This article collected opinions of respondents about the role that language plays in the process of learning and education. Subjects were asked about their preferred mediums of instruction and their feelings about studying in a particular medium of instruction. The study also focused on the reasons why the respondents opted for a certain medium of instruction. Relationships between proficiencies in the first and second language, i.e., Urdu and English were evaluated. Other findings were related to their proficiency in the first language, gender, place of residence, social pressure, the medium of instruction and quality of education. At the end, recommendations developed by researchers are to clarify the issues regarding the role of language in education.
Graphene Oxide Coatings Deposited on Steel Substrate Using Electrophoretic Deposition and Electrochemical Evaluation of Coatings in Saline Media
Authors: Rehman Zaeem Ur , Raza Mohsin Ali , Ghauri Faizan Ali , Kanwal Rumasa , Ahmad Akhlaq , Inam Aqil
Published: September 2018

In this study graphene coatings were deposited on mild steel substrate using feasible and environmental friendly method. The successful synthesis of graphite oxide was carried by the modified Hummer’s method. Graphene oxide (GO) coatings were developed from GO/water suspension using electrophoretic deposition (EPD). The EPD parameters voltage and deposition time were varied to deposit uniform adherent coatings. The coatings were post heat treated at 200 °C in vacuum for 4h to assess the effect on coated samples. GO and GO-EPD coating morphology were characterized using Fourier transform infrared spectroscopy (FTIR), Atomic force microscopy (AFM) and Scanning electron microscopy (SEM). Linear polarization (LPR) and electrochemical impedance spectroscopy (EIS) tests were performed in saline solution to evaluate electrochemical response. Coatings were partially reduced due to removal of oxygen containing functional groups during EPD and post heat treatments. The GO post heat treated coating had better corrosion resistance ~2 times than that of bare mild steel and higher charge transfer resistance.
Effect of Structural Modification on Corrosion Behavior of Hypo Eutectic Al-Si Alloy
Authors: Mansoor Muhammad , Kamran Yaseen Muhammad , Khan Shaheed
Published: September 2018

Al-Si eutectic cast alloys are widely used in aeronautical and automobile industries where significantly high strength, toughness and wear resistance are required. This class of cast alloys exhibit relatively low corrosion resistance in brine environments. The mechanical properties of the alloy system mainly depend upon the shape of Si rich eutectic phase, which mainly has acicular geometry. In present research, the effect of modified microstructure of 12 wt. % Si-Al alloy on corrosion behavior was studied. The needle like Si rich eutectic phase was modified to disperse spherical structure using rare earth metal halides. The corrosion rate and pitting behavior of modified and unmodified alloy were evaluated in 3.5% NaCl solution by general corrosion for calculated time. It was observed that the corrosion rate and pitting tendency of modified alloy had been appreciably reduced as compare to unmodified alloy. The improvement of corrosion properties were the attributes of changed morphology and distribution of Si rich eutectic phase.
Thermo-Physical Properties Measurement of Advanced TBC Materials with Pyrochlore and Perovskite Structures
Authors: Ejaz Noveed , Ali Liaqat , Ahmad Akhlaq , Mansoor Muhammad , Asim Muhammad Muneeb , Rauf Abdul , Mehmood Khalid
Published: September 2018

Thermal barrier coatings (TBCs) serve as thermal insulator in the hot region of an aircraft engine. Besides this, it also protects the underlying metal surface from the harsh corrosive and eroding environment. The associated lower thermal conductivity of TBC ceramic materials plays an important role in the improvement of thermal efficiency of the engine in term of increased combustion temperature and power. The thermal conductivity of the conventional yttria stabilized zirconia (YSZ) and three advanced ceramic materials with perovskite (CaZrO3) and pyrochlore structure (La0.75Nd0.25)2Zr2O7 & Nd2Ce2O7) have been determined using differential scanning calorimetry (DSC). With thin metallic disk on the ceramic samples of different heights were heated / scanned using a standard DSC apparatus. The results were evaluated for the thermal conductivity measurement using well established procedure /calculations. The analyzed results were compared with that of other techniques given by other researchers and found to be in good agreement with an error of 10-15%. The result of coefficient of thermal expansion (CTE) that was measured using a dilatometer up to 1273°K has also given.
Optimizing Cold Compression Deformation to Remove Residual Stresses in Die Forged Disc of Al-Mg-Si Alloy
Authors: Akhtar Naveed , Afzal Muhammad , Awais Muhammad , Akbar Muhammad
Published: September 2018

Quenching residual stresses in Al-Mg-Si alloy forged disc were balanced via cold deformation compression method. In this experiment firstly, the forged disc of Φ210x52 mm was prepared from extruded stock material of Φ160x90 mm through close die forging technique. Next, the forged discs were quenched in water and cold compressed immediately. Finally, the discs were artificial aged to finish in T652 temper. Close die forging and cold compression deformation was performed on a 1200 Ton hydraulic forging press. The amount of cold compression deformation was varied from 2.0 to 5.0% to gauge the optimum level of cold compression for the removal of quenching residual stresses. The residual stresses were measured in terms of dimensional stability of the machined component. Results showed that the 3.8% cold compression deformation was the optimized value for the work piece geometry under investigation. Further, the effect of cold (room temperature) and hot water (~60°C) quenching on the residual stresses was also studied and compared with that of cold compression method.
Tuning of Thermo-Mechanical Performance: Modified Multiwalled Carbon Nanotubes Reinforced SBR/NBR/SR Nanocomposites
Authors: Iqbal Sadia Sagar , Adrees Muhammad , Ahmad Adnan , Hassan Faiza , Yasir Muhammad , Bashir Arshad , Ahmad Sajid Rasheed , Jamshaid Fahd , Khan Waheed Gull
Published: September 2018

The present study aimed to identify the potential of modified nanoreinforcement (multiwalled carbon nanotubes; m-MWCNTs) to attenuate the thermal transport/decomposition/transition and mechanical aspects of three different polymeric matrices. In order to develop strong interfacial interaction between the host matrix and the incorporated nanotubes, 3-aminopropyletrimethoxy silane (APTMS) was used to m-MWCNTs. IR spectra confirmed the silane chemical moiety attachment on the upper surface of the MWCNTs. Conventional elastomeric mixing techniques were adopted to disperse m-MWCNTs within the three polymeric matrices (Acrylonitrile butadiene rubber, Silicone rubber, and Styrene Butadiene rubber) separately. SEM images assured the uniform dispersion of m-MWCNTs within the host polymeric matrices. Experimental evaluation of thermal conductivity revealed the reduction of thermal transport through the developed composite specimens by increasing the host polymer matrix to nanofiller concentration (m-MWCNTs). The utmost insulation effect was perceived in the F-MWCNTs incorporated silicone rubber nanocomposite comparatively. Glass transition/crystallization temperatures of the nanocomposites were lessened however melting temperatures were enhanced by impregnating nanotubes into the host polymeric matrices. Maximum thermal stability improvement due to the addition of m-MWCNTs was observed in the silicone elastomeric nanocomposite as compared to the other two systems. Proper dispersion and compatibility of m-MWCNTs with the polymeric matrices effectively enhanced the ultimate tensile strength (UTS)/elongation at break along hardness of rubber of the nanocomposites. The insulation character of m-MWCNTs/silicone rubber system was found best among the explored nanocomposite formulations.
Investigation of Various Nano-Structural Morphologies of Zinc Oxide for their Applications in Dye-Sensitized Solar Cells
Authors: Karim Muhammad Ramzan Abdul , bin Ahmed Muhammad , Ul Haq Ehsan , Mahmood Khalid , Hussain Azhar , Iqbal Sulaik Ullah , Shah Syed Abrar Hussain , Joya Yasir Faheem , Awan Ahmed Sher
Published: September 2018

In the current study, various morphologies of zinc oxide (ZnO) including nanorods, nanoflowers, nanosheets/flakes, nanospherical particles, nanohexagonal sheets, and nanoneedles have been prepared by using single step and two-step hydrothermal processes with optimized parameters such as growth temperature, growth time and compositions of both the seed and growth solutions. Fluorine doped tin oxide (FTO) coated glass was used as the substrate. The prepared morphologies were characterized with the help of scanning electron microscopy (SEM) and the purity of nanostructures was confirmed by elemental analysis (EDX). These nanostructures were used as photo-anode material to fabricate the DSSC using a dye (Rhodamine B) for enhancing the range of solar spectrum that is to be adsorbed. Finally the fabricated solar cells were characterized in terms of their efficiency, gauged by their fill factor. Among different morphologies investigated as photo anode materials; nanosheets/flakes were found to be showing maximum efficiency, with fill factor values around 0.5 due to their larger surface area, better porosity and enhanced capability of light trapping and scattering.
The impairment of the Growth Hormone/Insulin-like growth factor 1 (IGF-1) axis in heart failure: A possible target for future therapy
Authors: Piccioli Lucrezia , Arcopinto Michele , Salzano Andrea , D'Assante Roberta , Schiavo Alessandra , Stagnaro Francesca M. , Lombardi Anna , Panicara Veronica , Valente Pietro , Vitale Giuseppe , Sarullo Filippo M. , Giallauria Francesco , Marra Alberto M.
Published: September 2018

Hormonal abnormalities are quite common in chronic heart failure (CHF). The most studied hormonal axis in CHF is the impairment of Growth Hormone (GH)/Insulin Growth Factor-1(IGF-1), which in turn is defined either by a blunted response to GH stimulation test or low serum IGF-1 values. Â Several independent groups reported that the presence of an abnormal GH/IGF-1 status in CHF is associated with a more severe disease, impaired functional capacity and reduced Survival rates. After the first encouraging results, double -blind controlled trials showed a neutral effect of the GH administration in patients. However, further studies reported positive results, when a GH-therapy is implemented only in those patients presenting a GH deficiency (replacement therapy).
Adverse Drug Reaction Reporting: Opportunities to Increase Pharmacists’ Role
Authors: Shalansky Stephen
Published: September 2018

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La déclaration des réactions indésirables aux médicaments : une occasion d’étendre le rôle des pharmaciens
Authors: Shalansky Stephen
Published: September 2018

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Identifying Drug Interactions between Enzalutamide and Complementary Alternative Medications in a Patient with Metastatic Prostate Cancer: A Case Report
Authors: Brownlee Thomas , Olson Colleen , Deschamps Michelle
Published: September 2018

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Bridging the Gap: Interdepartmental Quality Improvement and Patient Safety Curriculum Created by Hospital Leaders, Faculty, and Trainees
Authors: Miller Megan E. , Patel Ajanta , Schindler Nancy , Hirsch Kristen , Ming Mei , Weber Stephen , Turner Phyllis , Howell Michael D. , Arora Vineet M. , Oyler Julie L.
Published: September 2018

Background 

The Accreditation Council for Graduate Medical Education Clinical Learning Environment Review recommends that quality improvement/patient safety (QI/PS) experts, program faculty, and trainees collectively develop QI/PS education.

Objective 

Faculty, hospital leaders, and resident and fellow champions at the University of Chicago designed an interdepartmental curriculum to train postgraduate year 1 (PGY-1) residents on core QI/PS principles, measuring outcomes of knowledge, attitudes, and event reporting.

Methods 

The curriculum consisted of 3 sessions: PS, quality assessment, and QI. Faculty and resident and fellow leaders taught foundational knowledge, and hospital leaders discussed institutional priorities. PGY-1 residents attended during protected conference times, and they completed in-class activities. Knowledge and attitudes were assessed using pretests and posttests; graduating residents (PGY-3–PGY-8) were controls. Event reporting was compared to a concurrent control group of nonparticipating PGY-1 residents.

Results 

From 2015 to 2017, 140 interns in internal medicine (49%), pediatrics (33%), and surgery (13%) enrolled, with 112 (80%) participating and completing pretests and posttests. Overall, knowledge scores improved (44% versus 57%, P < .001), and 72% of residents demonstrated increased knowledge. Confidence comprehending quality dashboards increased (13% versus 49%, P < .001). PGY-1 posttest responses were similar to those of 252 graduate controls for accessibility of hospital leaders, filing event reports, and quality dashboards. PGY-1 residents in the QI/PS curriculum reported more patient safety events than PGY-1 residents not exposed to the curriculum (0.39 events per trainee versus 0.10, P < .001).

Conclusions 

An interdepartmental curriculum was acceptable to residents and feasible across 3 specialties, and it was associated with increased event reporting by participating PGY-1 residents.
Ice nucleating particles in the marine boundary layer in the Canadian Arctic during summer 2014
Authors: Irish Victoria E. , Hanna Sarah J. , Willis Megan D. , China Swarup , Thomas Jennie L. , Wentzell Jeremy J. B. , Cirisan Ana , Si Meng , Leaitch W. Richard , Murphy Jennifer G. , Abbatt Jonathan P. D. , Laskin Alexander , Girard Eric , Bertram Allan K.
Published: September 2018

Abstract. Ice nucleating particles (INPs) in the Arctic can influence climate and precipitation in the region; yet our understanding of the concentrations and sources of INPs in this region remain uncertain. In the following we (1) measured concentrations of INPs in the Canadian Arctic marine boundary layer during summer 2014 on board the CCGS Amundsen, (2) determined ratios of surface areas of mineral dust aerosol to sea spray aerosol, and (3) investigated the source region of the INPs using particle dispersion modelling. Average concentrations of INPs at −15, −20 and −25 °C were 0.005, 0.044, and 0.154 L−1, respectively. These concentrations fall within the range of INP concentrations measured in other marine environments. For the samples investigated the ratio of mineral dust surface area to sea spray surface area ranged from 0.03 to 0.09. Based on these ratios and the ice active surface site densities of mineral dust and sea spray aerosol determined in previous laboratory studies, our results suggest that mineral dust is a more important contributor to the INP population than sea spray aerosol for the samples analysed. Based on particle dispersion modelling, the highest concentrations of INPs were often associated with lower latitude source regions such as the Hudson Bay area, eastern Greenland, or northwestern continental Canada. On the other hand, the lowest concentrations were often associated with regions further north of the sampling sites and over Baffin Bay. A weak correlation was observed between INP concentrations and the time the air mass spent over bare land, and a weak negative correlation was observed between INP concentrations and the time the air mass spent over ice and open water. These combined results suggest that mineral dust from local sources is an important contributor to the INP population in the Canadian Arctic marine boundary layer during summer 2014.
Influence of an Electrically Non-Conducting Heat Sink for Power Semiconductors on Radiated Interferences
Authors: Chromy Stephan , Rathjen Kai , Fahlbusch Sebastian , Hoffmann Klaus F. , Dickmann Stefan
Published: September 2018

Abstract. Power semiconductors are used in a growing number of applications.
Furthermore, faster switching transients and therefore higher switching
frequencies can be realised. This leads to higher radiated interferences at
higher frequencies. In power electronic applications, often a cooling concept
for the semiconductors is required to comply with the allowed temperature
range. Typically, heat sinks are made of aluminium and their conductive
behaviour can cause EMC problems. Via capacitive coupling, voltage transients
are transferred from the power semiconductor to the heat sink, so that the
heat sink behaves as an antenna and radiated interferences occur.
Furthermore, a common mode current will appear if the heat sink is grounded.
In this paper, a promising approach to reduce radiated interferences from the
heat sink and solve the common mode issue by using an electrically isolating
ceramic heat sink is presented. The influence of an aluminium nitride ceramic
heat sink on cooling performance and EMC behaviour has been investigated. For
this purpose, two geometrical identically heat sinks made from aluminium and
aluminium nitride have been compared regarding thermal performance and
radiated interferences characterised by S-parameters.
Assimilation of wind data from airborne Doppler cloud-profiling radar in a kilometre-scale NWP system
Authors: Borderies Mary , Caumont Olivier , Delanoë Julien , Ducrocq Véronique , Fourrié Nadia
Published: September 2018

Abstract. The article reports on the impact of the assimilation of wind vertical profile data in a kilometre-scale NWP system on predicting heavy precipitation events in the north-western Mediterranean area. The data collected in diverse conditions by the airborne W-band radar RASTA (Radar Airborne System Tool for Atmosphere) during a 45-day period are assimilated in the 3-h 3DVar assimilation system of AROME. The impact of the length of the assimilation window is investigated. The data assimilation experiments are performed for a heavy rainfall event, which occurred over south-eastern France on 26 September 2012 (IOP7a), and over a 45-day cycled period. During IOP7a, results indicate that the quality of the rainfall accumulation forecasts increases with the length of the assimilation window. By contrast, on the 45-day period, the best scores against rain gauges measurements are reached with a 1 hour assimilation window, which recommends to use observations with a small period centred on the assimilation time. The positive impact of the assimilation of RASTA wind data is particularly evidenced for the IOP7a case since results indicate an improvement in the predicted wind at short term ranges (2 hours and 3 hours) and in the 12-hour precipitation forecasts. However, on the 45-day cycled period, the comparison against other assimilated observations shows an overall neutral impact. Results are still encouraging since a slight positive improvement in the 6-, 9- and 12-hour precipitation forecasts of heavier rainfall was demonstrated.
Levantamento Arbóreo Da Caatinga No Campus IV Da UEPB Em Catolé Do Rocha, PB
Authors: Guimarães Luciana Menino , LINHARES Anne Carolline Maia , SILVA Sonaria de Sousa , Da SILVA Damião Pedro , COSTA Fabiana Xavier
Published: September 2018

RESUMO: O bioma Caatinga, é o maior e mais importante da Região Nordeste do Brasil. objetivou-se com esse trabalho quantificar as espécies arbóreas da UEPB Campus IV nos setores de Oleaginosas e do açude. O presente estudo foi realizado no Campus IV da Universidade Estadual da Paraíba no Município de Catolé do Rocha, a pesquisa se deu nos setores de Oleaginosas e setor do Açude. O total de árvores encontradas durante a presente pesquisa no setor de Oleaginosas foram de 1.645 indivíduos sendo 14 famílias, onde a família da Rosaceae (marmeleiro) apresenta-se em maior quantidade seguida da fabáceae (Feijão bravo) e Leguminosae (jurema preta e jurema branca). O total de árvores encontradas durante a presente pesquisa no setor do Açude foram de 51 indivíduos sendo 7 famílias, onde a família das Bignoniaceae (Pau d'arco) apresenta-se em maior quantidade seguida da Caesalpiniaceae (Mororó) e Leguminosae (jurema preta e jurema branca).  As espécies estudadas apresentam as mesmas características fenológicas vistas para outras áreas de florestas da caatinga.
‘cabos Verdes’ Que Não São Verde E Garrafas D’luz Que Têm Água: Entre Um País E Um Projecto
Authors: Alves Inês , Plácido Lara
Published: September 2018

O projecto Garrafa d’Luz surge como ponto de partida para uma reflexão sobre o lugar de Cabo Verde no mundo e sobre a forma como tem descoberto o seu caminho desde a sua independência. São pensadas as questões de sustentabilidade deste território insular, passando pelo turismo e pelo problema da habitação, focando sobre os principais intervenientes de um país em crescimento: a sua população. Após uma breve reflexão sobre os seus últimos 40 anos de história, é apresentado e explorado o projecto Garrafa d’Luz, solução essa que se tem centrado na intervenção pontual ao nível da iluminação diurna de casas de lata nas periferias do Mindelo, Ilha de São Vicente.
Digital Skills for Elderly People: A Learning Experiment in Four European Countries
Authors: Blažič Andrej Jerman , Blažič Borka Jerman
Published: September 2018

The problem of learning digital skills among the elderly addressed in this paper is focused on a methodology that tries to overcome the barriers in adoption of touchscreen digital technology faced by older adults, by using a game-based learning approach. The paper provides an overview of some early results and findings from an exploratory study among the elderly from four European countries based on the use of touchscreen tablets for playing games as a pre-course activity for learning how to use a smart phone. The learning was carried out with pre-selected games designed to enhance the motor skills of the players and improve the coordination between cognitive and motor skills capacity. The results presented in the paper were collected within the partners of the project GIRDA – Gameplay foR Inspiring Digital Adoption from the European ERASMUS+ programme. The paper describes the research setting, the experiments and the results accompanied by discussion and the conclusion.
De afnemende rol van de rechtspraak: is vervanging van de rechter mogelijk en wenselijk?
Authors: Malsch Marijke
Published: September 2018

The diminishing role of the Judiciary: is replacement of the judge possible and desirable?

The last decades have shown a tendency in which tasks are transferred from the judge to other authorities, such as the police and public prosecutor, administrative bodies, administrative procedures, or private parties. The central question in this article is whether these authorities can really replace the court. A comparison is made between legal proceedings and procedures for other authorities on the following aspects: truth finding, openness and legal protection of the (vulnerable) citizen. The author also discusses a recent legislative proposal for an own budget for the Judiciary, which aims to strengthen the independence of the judge towards the two other state powers. It is argued that the courts should be also accessible in the case of relatively small offenses and for vulnerable citizens.
Het zwaard van Damocles: burgemeesters wil is wet
Authors: Schaap Maartje
Published: September 2018

Damocles law: On the punitive nature of an administrative measure in the Netherlands

Under Article 13b (1) of the Dutch Opium Act, the mayor is authorized to impose an order under administrative coercion when drugs are sold, delivered, supplied or present in houses or premises This much-discussed article, also cited as the ‘Damocles Law’, gives the mayor the power to close drug shelters even before the suspect’s guilt has been established in legal proceedings. It is not necessary to show that the interests of public policy are at stake. Moreover, the means of defense against the closure are very limited. The author argues that the current application of Article 13b is exclusively punitive in nature, whereby in case of criminal prosecution, there is also a violation of the ne bis in idem principle.
Tirkkonen: besluiteloosheid wordt beloond?
Authors: Nijhof B.
Published: September 2018

Tirkkonen: besluiteloosheid wordt beloond?

Het Hof van Justitie oordeelt dat Aanbestedingsrichtlijn 2004/18/EG geen toepassing vindt bij een systeem waar potentiële opdrachtnemers slechts hoeven te voldoen aan toelatingseisen, zonder dat de aanbestedende dienst uiteindelijk een keuze maakt voor specifieke opdrachtnemers op basis van onderscheidende criteria. Daarbij is het irrelevant dat dat systeem niet ‘open house’ is.

HvJ 1 maart 2018, zaak C-9/17, Maria Tirkkonen/Maaseutuvirasto, ECLI:EU:C:2018:142
Terugvordering van staatssteun vindt zijn plek in de Nederlandse wetgeving
Authors: van Haersolte J.C.
Published: September 2018

Terugvordering van staatssteun vindt zijn plek in de Nederlandse wetgeving

Per 1 juli 2018 heeft het staatssteunrecht zijn plek gevonden in de Nederlandse regelgeving. Althans, de terugvordering van onrechtmatige staatssteun. Wat regelt de Wet terugvordering staatssteun?

Wet Terugvordering staatssteun (in werking getreden op 1 juli 2018), Stb. 2018, 99
A Conferência de Medellín: contexto político-eclesial e a posição sobre a Educação e a Juventude
Authors: Siqueira Giseli do Prado , Baptista Paulo Agostinho Nogueira , Teodoro-Silva Wellington
Published: September 2018

A Segunda Conferência Geral do Episcopado Latino-americano, realizada na cidade de Medellín (Colômbia), entre os dias 24 de agosto e 06 de setembro de 1968, produziu um importante e significativo documento – As Conclusões de Medellín – que registraram as posições da Igreja da América Latina, que assumiu uma posição libertadora frente à opressão no continente. O objetivo do Papa Paulo VI, como diz o próprio título da proposta da Conferência, era ler a realidade latino-americana à luz do Concílio Vaticano II. Os bispos fizeram mais do que isso: leram o Concílio à luz da realidade latino-americana. Nesse contexto, o objetivo deste artigo, a partir de pesquisa bibliográfica, é apresentar alguns elementos da realidade política e eclesial de Medellín e analisar dois aspectos do documento: a educação e a juventude. A década de 1960 e, particularmente o ano de 1968, são momentos históricos efervescentes, contexto da guerra-fria, impactando muitas mudanças. Igreja assume de forma clara o trabalho de inserção nas comunidades pobres. A educação passa a ser pensada numa perspectiva libertadora, há a inserção dos religiosos nas comunidades de base. A juventude católica assume compromissos socais e políticos. Em Medellín ganha identidade própria a Igreja latino-americana e uma forma original de fazer teologia, a teologia da libertação e sua opção pelos pobres. Também o exercício da colegialidade dá passos importantes, inclusive na forma de elaboração do documento. Portanto, celebrar 50 anos desse documento deve levar o olhar crítico para seus valores e limitações e recuperar seus avanços, contribuindo para o debate no campo das Ciências da Religião.
Medellín: inspiração para uma metodologia do diálogo inter-religioso
Authors: Panasiewicz Roberlei
Published: September 2018

A Conferência do Episcopado Latino-Americano de Medellín (1968) inaugurou um "novo tempo" para a Igreja Católica na América Latina. Realizada após o Concílio Vaticano II (1962-1965), recebe e atualiza as suas percepções e dá origem a "igreja dos pobres". Teve visão e prática proféticas ao compreender o pensar pastoral e teológico a partir "de baixo". O sofrimento dos oprimidos e seu grito por justiça foram escutados. Assumir o método ver-julgar-agir na estruturação do documento e no pensar a prática pastoral e teológica foram fundamentais para o emergir de um "novo jeito" de ser da Igreja católica no continente. Entretanto, em que este método pode inspirar novas construções dialógicas na atualidade? Em que contribui para a parceria entre Teologia da Libertação e Teologia do Pluralismo Religioso? Estas respostas configuram a estrutura deste artigo, bem como o seu objetivo: compreender como a inspiração metodológica de Medellín auxilia na construção de diálogos inter-religiosos na atualidade em vista de maior compreensão do Mistério Transcendente e da transformação social. Primeiramente, serão apresentadas as críticas feitas por Medellín à metodologia pastoral da época; em seguida, será apontada a configuração de nova metodologia pastoral; por fim, será sinalizado como esta metodologia, assumida por Medellín, inspira a construção de diálogos inter-religiosos na contemporaneidade.
A Pentecostalização de Povos Tradicionais na Amazônia: aspectos conceituais para uma antropologia de identidades religiosas
Authors: Rodrigues Donizete , De Moraes Júnior Manoel Ribeiro
Published: September 2018

Este artigo é um trabalho de enquadramento conceitual, que suporta pesquisas etnográficas que enfocam a presença e a dinâmica religiosa do protestantismo-pentecostalismo na Amazônia. A hipótese que estofa epistemologicamente este texto - e os projetos antropológicos já em andamento e futuros - formula a ideia de que o aspecto étnico-cultural “caboclo”, como ‘tipo ideal’ (no sentido weberiano), é um factor crucial nas dinâmicas evangélicas nesta região. Esta construção conceptual está presente, entre outros, em teóricos como Eduardo Galvão, Heraldo Maués, Angélica Mota Maués e João de Paes Loureiro – estudiosos da cultura amazônica. O objetivo é estudar as dinâmicas históricas e registrar, etnograficamente, as manifestações de movimentos missionários, de igrejas (neo)pentecostais e também de grupos menos institucionalizados, materializadas no forte processo de conversão e evangelização de comunidades tradicionais (indígenas, ribeirinhos, caboclos e populações peri-urbanas). O foco é analisar o impacto destas expressões religiosas em diversos tipos de grupos socioculturais amazónicos e de que forma estas comunidades, agora convertidas, ressignificam, criam e desenvolvem novas expressões do sagrado, formando o que estamos a denominar de ‘pentecostalismo caboclo’.
Securing community-controlled infrastructure: SPARC’s plan of action
Authors: Joseph Heather
Published: September 2018

Late last year, the news of Elsevier’s acquisition of bepress, the provider of the popular Digital Commons repository platform, sent a shockwave throughout the library community. Hundreds of institutions that use Digital Commons to support their open access repositories quite literally woke up to the news that their repository services are now owned and managed by a company that is well known for its obstruction of open access in the repository space.
Donald J. Trump: un análisis crítico del discurso
Authors: Mena García Tomás
Published: September 2018

Donal J. Trump resulta ser un Presidente fuera de lo común que genera polémicos titulares en todo el mundo. ¿Por qué provoca tanta atracción y polémica? ¿Qué novedades aporta? Este estudio pretende responder a estas cuestiones desde una perspectiva del análisis crítico del discurso. El ensayo está dividido en tres capítulos. En el primero se exponen los aspectos más característicos de su estilo discursivo. El segundo se dedica a estudiar la influencia de los modelos de familia en Trump analizados por el lingüista cognitivo George Lakoff, centrándose en los siguientes tipos: el Padre estricto y el Progenitor nutriente.  El tercero y último capítulo se consagra a estudiar el modo en que “el otro” es representado por Trump. Se aborda en este trabajo el tratamiento de temas como el racismo, la inmigración o su visión de “la clase dirigente”. Donald J. Trump is an “off the spectrum” President who creates controversial headlines of the media around the world. Where does his appeal come from? What is new about him? This paper tries to answer these questions from a Critical Discourse Analysis perspective. The essay is divided into three chapters. The first one gives a general overview of Trump’s discourse styles. The second one deals with the family model developed by George Lakoff in terms of metaphors and more specifically with the representation of the strict father pattern in Trump’s discourse. The third and final chapter is dedicated to the portrayal of “the other” in Trump. Strategies to depict “otherness” are analysed from an ideological discourse viewpoint. Racism, immigration and Trump’s depiction of “the establishment” are not neglected.
Protocolo y Relaciones Institucionales
Authors: Merchán Rodriguez M.ª de los Ángeles
Published: September 2018

La consecución de objetivos se produce tras un proceso de desarrollo y potenciación de las competencias. Ahora bien, ¿y si existiese una metodología que nos permitiese conectar con nuestro propio liderazgo, desarrollar nuestras potencialidades y manifestar la excelencia? ¿Y si esta metodología fuese aplicada de forma específica por y para los profesionales del Protocolo? ¿Y, además, tuviese un beneficio directo sobre la actividad de Relaciones Públicas de la organización?                                                                                                                                                                                                                                                                                                                                                                                                                                         El objetivo de esta comunicación es aportar a los protocolistas distintas herramientas y una metodología específica que les faculte para el desarrollo de un nuevo liderazgo para el s.XXI. En la realización de este proceso obtendrán un beneficio personal que reportará directamente sobre las organizaciones para las que trabajan.________________________________The achievement of objectives happens after a process of development and empowerment of competencies. Now, what if there were a methodology that allowed us to connect with our own leadership, develop our potential and manifest excellence? What if this methodology were applied specifically by and for the professionals of Protocol? And, besides, had a direct benefit on the activity of Public Relations of the organization?  The objective of this communication is to provide the protocolists with different tools and a specific methodology that enables them to develop a new leadership for the XXI century. Carrying out this process, you will obtain a personal benefit that will directly report to the organizations for which you work.
Reseña del libro los Básicos del Protocolo
Authors: Sánchez González Dolores del Mar
Published: September 2018

reseña del libro Los básicos del Protocolo
A two-hybrid antibody micropattern assay reveals specific in cis interactions of MHC I heavy chains at the cell surface
Authors: Dirscherl Cindy , Hein Zeynep , Ramnarayan Venkat Raman , Jacob-Dolan Catherine , Springer Sebastian
Published: September 2018

We demonstrate a two-hybrid assay based on antibody micropatterns to study protein-protein interactions at the cell surface of major histocompatibility complex class I (MHC I) proteins. Anti-tag and conformation-specific antibodies are used for individual capture of specific forms of MHC I proteins that allow for location- and conformation-specific analysis by fluorescence microscopy. The assay is used to study the in cis interactions of MHC I proteins at the cell surface under controlled conditions and to define the involved protein conformations. Our results show that homotypic in cis interactions occur exclusively between MHC I free heavy chains, and we identify the dissociation of the light chain from the MHC I protein complex as a condition for MHC I in cis interactions. The functional role of these MHC I protein-protein interactions at the cell surface needs further investigation. We propose future technical developments of our two-hybrid assay for further analysis of MHC I protein-protein interactions.
Timing of the reticular lamina and basilar membrane vibration in living gerbil cochleae
Authors: He Wenxuan , Kemp David , Ren Tianying
Published: September 2018

Auditory sensory outer hair cells are thought to amplify sound-induced basilar membrane vibration through a feedback mechanism to enhance hearing sensitivity. For optimal amplification, the outer hair cell-generated force must act on the basilar membrane at an appropriate time at every cycle. However, the temporal relationship between the outer hair cell-driven reticular lamina vibration and the basilar membrane vibration remains unclear. By measuring sub-nanometer vibrations directly from outer hair cells using a custom-built heterodyne low-coherence interferometer, we demonstrate in living gerbil cochleae that the reticular lamina vibration occurs after, not before, the basilar membrane vibration. Both tone- and click-induced responses indicate that the reticular lamina and basilar membrane vibrate in opposite directions at the cochlear base and they oscillate in phase near the best-frequency location. Our results suggest that outer hair cells enhance hearing sensitivity through a global hydromechanical mechanism, rather than through a local mechanical feedback as commonly supposed.
The Potential of The Big Data Implementation, in Serbia, in the context of Marketing Research
Authors: Zekavica Ana Miodrag , Djordjevic Aleksandar , Vukmirovic Aleksandra , Vukmirovic Jovanka , Brankovic Milica
Published: September 2018

Research question: Big Data represents a true business revolution in many areas, and, as such, in marketing research, as well. The subject of this study is the analysis of the existing stage, as well as of the achieved results in the implementation of the Big Data Technology in Serbia. Motivation: The success in managing the company depends on the ability to provide quality and comprehensive information by establishing personalized (1:1) communication with consumers on the global market in real or near real-time. This form of communication has become an imperative of the modern business decision-making process. Advanced Internet technologies, Cloud Computing (Cloud Technology), Big Data and Artificial Intelligence open a significant business potential for companies in Serbia to emerge on global markets. Idea: of this study is to perceive current business environment in Serbia through the prism of research development based on the Big Data technologies. Relevant hypotheses and conducted research have been set up with the aim of pointing to the potential of applying modern information-communication technologies, with an emphasis on artificial intelligence and the Big Data concept. Data: The survey was conducted on 154 business entities from the Serbian Business Register Agency’s database. The applied sampling method was a random analysis (selection was made randomly from the total number of selected companies, with the same probability of choice). Tools: An online survey was used, and respondents were contacted via e-mail. Findings: Research results, opinions and attitudes of managers, experts in the fields of marketing research and information technology, indicate a significant degree of justifiability of investments in new technologies in the Republic of Serbia and result in several proposals of certain measures and recommendations of incentives that should be conducted by the State. Contribution: The solutions in this paper are based upon the implementation of standardized procedures and advanced tools that could be used to overcome a "bottleneck" in the existing IT infrastructure, in order to enable a rapid collection and implementation of enabled data.
Identification of candidate genes and proteins in aging skeletal muscle (sarcopenia) using gene expression and structural analysis
Authors: Shafiee Gita , Asgari Yazdan , Soltani Akbar , Larijani Bagher , Heshmat Ramin
Published: September 2018

Sarcopenia is an age-related disease characterized by the loss of muscle mass and muscle function. A proper understanding of its pathogenesis and mechanisms may lead to new strategies for diagnosis and treatment of the disease. This study aims to discover the underlying genes, proteins, and pathways associated with sarcopenia in both genders. Integrated analysis of microarray datasets has been performed to identify differentially expressed genes (DEGs) between old and young skeletal muscles. Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were then performed to uncover the functions of the DEGs. Moreover, a protein–protein interaction (PPI) network was constructed based on the DEGs. We have identified 41,715 DEGs, including 19 downregulated and 41,696 upregulated ones, in men. Among women, 3,015 DEGs have been found, with 2,874 of them being upregulated and 141 downregulated genes. Among the top up-regulated and downregulated genes, the ribosome biogenesis genes and genes involved in lipid storage may be closely related to aging muscles in men and women respectively. Also, the DEGs were enriched in the pathways including those of ribosome and Peroxisome proliferator-activated receptor (PPAR) in men and women, respectively. In the PPI network, Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1), Cullin 3 (CUL3) and P53 have been identified as significant hub proteins in both genders. Using the integrated analysis of multiple gene expression profiles, we propose that the ribosome biogenesis genes and those involved in lipid storage would be promising markers for sarcopenia in men and women, respectively. In the reconstructed PPI network, neurotrophic factors expressed in skeletal muscle are essential for motoneuron survival and muscle fiber innervation during development. Cullin E3 ubiquitin ligase (Cul3) is an important component of the ubiquitin–proteasome system—it regulates the proteolysis. P53 is recognized as a central regulator of the cell cycle and apoptosis. These proteins, which have been identified as the most significant hubs, may be involved in aging muscle and sarcopenia.