bluuebunny/crossref_metadata_2025 huggingface dataset:
The specifics of emotional dysregulation in women with various types of irritable bowel syndrome
Authors: Melehin Aleksey I.
Published: April 2022

BACKGROUND. To this day, relatively little is known about the specifics and mechanisms by which psychological factors, such as a general tendency to anger and the style of expressing anger, can be associated with pro-inflammatory processes and visceral hypersensitivity, which contribute to the appearance of signs of irritable bowel syndrome and lead to its refractory course.
AIM. The purpose of the work. to identify the specifics of differences in the presence and severity of depression, anxiety, anger expression and satisfaction with the quality of life in women (average age 39.210.6) with refractory IBS of constipated, diarrheal and mixed types (duration of the disease 33.848.1 months), based on the hypothesis that women with different types of IBS may have different styles of expressing negative emotions (for example, anger) and ways of controlling behavior.
MATERIAL AND METHODS. PHQ-15 Patient Health Questionnaire-15; GAD-7 General Anxiety Disorder-7; PHQ-9 Patient Health Questionnaire-9; IBS-QOL Irritable Bowel Syndrome Quality of Life; STAXI StateTrait Anger Expression Inventory.
RESULTS. Correlations between subtypes of IBS and negative aspects of the emotional sphere are observed and it is shown that subtypes of IBS-C and IBS-D demonstrate affective profiles characterized by a higher level of anxiety, depression and changes in the expression of anger with difficulties of expression both verbally and nonverbally. All types are characterized by autoaggression, suppression of anger, but these aspects are more pronounced in IBS-D and IBS-C. There is intense control of anger expression. With IBS-C and IBS-M, there is greater control over the expression of anger externally than with IBS-D. Women with IBS-C have more pronounced indicators of anger as a mental state. There are difficulties in verbal expression of anger, hetero- and autoaggression. Anger is a trait of character and is included in the structure of temperament. Women with IBS-D have pronounced indicators of anger as a reaction to a current life event, autoaggression, anger control inside. The level of affect somatization, the presence and severity of generalized anxiety disorder, depression, changes in life satisfaction are among the predictors that determine both the level of anger and the ways of its expression.
CONCLUSION. Intestinal motility can be considered as an indicator of behavior control, as an indicator of the regulatory function of the patient, the intensity of affective involvement in a particular situation. Changes in the cognitive, emotional and executive components of the mental organization play only a significant role in the refractory course of IBS.
Social and medical practices of gender transition in Russia
Authors: Chumakov Egor M. , Petrova Nataliia N. , Ashenbrenner Yulia V. , Azarova Larisa A. , Limankin Oleg V.
Published: April 2022

AIM. To examine the social and medical aspects of gender transition practices in Russia.
MATERIAL AND METHODS. An anonymous online survey of people living in Russia whose gender experience differed from the sex marker determined at birth was conducted. The final sample consisted of 588 respondents (aged 24.016.70), of whom 69.9% (n=409) were transgender male, 23.1% (n=136) were transgender female, and 7.3% (n=43) had a different gender identity.
RESULTS. There was a high frequency of social disadaptation among respondents (15.5% of the sample). Most respondents first reflected that their gender identity did not match their sex at birth and/or did not fit into the social framework during childhood or adolescence, with a peak at age 1114 (39.8% of the entire sample). The age at which respondents began gender transition was overwhelmingly after adulthood, with a peak at age 1825 (32.0% of the entire sample). More than half of the respondents (59.4%) who had medical body changes associated with gender transition initiated them on their own. Less than half of the respondents who were on hormone therapy (41.0%) had been monitored by an endocrinologist. The study showed a large proportion of people who already had medical body changes but had not changed sex marker on their IDs, with transgender women having the largest rate in this indicator.
CONCLUSION. The data obtained determine the relevance of developing a system of specialized medical care for transgender people with essential destigmatizing psychotherapeutic and psychiatric care for these people, as well as emphasize the need to study the availability of medical (psychiatric) care for transgender people living in Russia.
Low-Noise Optical Accelerometers: Bridging the Gaps among Geophones, Accelerometers, and Broadbands in a Deep Borehole
Authors: Hopp Chet , Taira Taka’aki , Robertson Michelle , Farrugia Joseph J. , Layland-Bachmann Corinne , Majer Ernie
Published: April 2022

Earthquakes and other seismic sources produce waves with frequency content spanning many orders of magnitude. Recording a broader frequency band of interest has historically required deploying multiple instruments designed to work the best within limited, overlapping frequency ranges. Here, we detail a 300 m deep borehole deployment of a sensor package, including three new optical accelerometers that can potentially replace many dedicated instruments with a single, low-noise sensor. These instruments are designed with a flat frequency response from 0.005 to 1500 Hz, spanning the flat response segments of broadband sensors and geophones, as well as a low-noise floor and high sensitivity. The sensors have been functioning normally for over four years, fully grouted at depths of >100 m. Year-long power spectral density (PSD) profiles show that the optical accelerometers have a lower noise floor than a colocated geophone for all frequencies, with 20 dB noise reduction at 250 Hz. PSD comparisons to a broadband sensor installed at the surface show a 5–30 dB noise reduction for the optical accelerometer above 1 Hz, although this is likely due, in part, to the broadband sensor being subjected to much higher surface noise. At periods >5 s, the broadband sensor shows up to 20 dB lower noise than the optical accelerometer, which in turn has up to 50 dB lower noise floor than the colocated geophone. Finally, modeling the Brune displacement spectrum for theoretical seismicity within 1 km of the borehole shows that the optical accelerometers could potentially deliver a detection threshold improvement of one magnitude unit relative to the colocated geophone.
Features of the Composition of Cytokines of Various Biological Effects in Patients with Uveal Melanoma: Local Changes in the Lacrimal Fluid. Part 1
Authors: Neroev V. V. , Saakyan S. V. , Katargina L. A. , Balatskaya N. V. , Kulikova I. G. , Myakoshina E. B.
Published: April 2022

Purpose. Conduct an extended analysis of the cytokine status and its role in inflammatory processes in uveal melanoma based on multiplex analysis of the tear fluid.

Patients and methods. Immunological studies of blood serum and lacrimal fluid were performed in 80 patients with uveal melanoma and 38 healthy donors (control group). The average age of the surveyed was 53.7 ± 12.2 years. Group 1 included 32 patients with small-sized choroidal melanoma (T1NoMo), group 2 consisted of 26 patients with medium-sized lesions (T2NoMo), group 3 — 22 patients with large tumor sizes (T3NoMo). The cytokine content in the tear fluid was determined by the method of multiplex analysis on the xMAP platform in the Luminex xPONENT 3.1 software using 47 plex kits (ProcartaPlex, eBioscience, Austria).

Results. In the lacrimal fluid of the patient and the paired eye — an increase in pro-inflammatory (IL-1α, IL-2, IL-6, IL-17A, IL-18, TNF-α, MCP-1, MIP-1α, RANTES, GRO-α, IL-8, IP-10), anti-inflammatory (IL-1RA, IL-4, IL-10, IL-5, TGF-1β), proliferative (FGF-2, HGF, IL-15, PDGF-BB, Eotaxin), pro-tumor (NGF-β, IL-7), antitumor (IL-21), angiogenic (VEGF-A, SDF-1α) cytokines in the initial stage of uveal melanoma compared with the control group, p < 0.05.

Conclusion. In response to the manifestation and growth of uveal melanoma, many chemoattractant mediators are produced, including pro-inflammatory and angiogenic effects, which promote tumor progression and affect the body’s immune response. The study of the lacrimal fluid proved the imbalance of the local immunity not only of the patient, but also of the paired «healthy eye». Research into cytokines leads to a deeper understanding of the pathophysiology of carcinogenesis and may contribute to the development of targeted therapies for inhibiting tumor growth.
Analysis of Clinical Study Results Obtained in Patients with Neovascular Age-Related Macular Degeneration in 2005–2020. Review
Authors: Gavrilova N. A. , Gadzhieva N. S. , Tishchenko O. E. , Zinov’eva A. V.
Published: April 2022

Currently, there is a wide range of antiglaucoma drugs. Ophthalmologists are faced with the task of choosing certain drugs and their combinations for specific patients. In this regard, studies aimed at studying the effectiveness of treatment, not only in terms of IOP indicators and instrumental research methods, but also in terms of the choice of a particular type of therapy by ophthalmologists, are of great interest. Purpose: to analyze the data obtained in the course of the study of the Russian multicenter scientific program: “Analysis of the assortability of ophthalmologists when choosing therapy within the framework of routine medical care in patients with primary open-angle glaucoma (POAG)”. The large-scale statistical study carried out was based on the study of 197 medical questionnaires from 61 cities of Russia, containing information on 6851 clinical cases. Doctors were asked to fill out a questionnaire based on the results of treatment (at least 2 months), taking into account the following criteria: satisfaction with treatment, adherence to treatment, accessibility, tolerability and ease of use of drugs. Evaluated the use of 5 antiglaucoma drugs of the company Sentiss Russ, belonging to different pharmacological groups: Prolatan (latanoprost), Bimatan (bimatoprost), Brinex-M (brinzolamide); Tisoptan (bimatoprost / timolol maleate), Brinarga (brinzolamide / timolol maleate). During the study, patients were divided into 6 groups depending on the drug used, and also into 3 groups depending on the stage of primary POAG. The data obtained indicate a statically high level of average values when using the point system of all the above criteria when using these drugs. When analyzing the degree of convenience and the level of tolerance of drugs, a tendency towards a decrease in the average scores of these indicators in patients with advanced stage of glaucoma was noted, which may be due to the long-term use of antiglaucoma therapy in this category of patients with changes in the ocular surface. 98.25% of doctors expressed their intention to continue prescribing antiglaucoma drugs from Sentiss Russ.
Modern Methods for the Diagnosis of Morphological and Functional Features of the Retina in Dysbinocular and Anisometropic Amblyopia
Authors: Khubieva R. R. , Tarutta E. P.
Published: April 2022

Child health is a global health priority. Anomalies of refraction, complicated by amblyopia and squint, occupy one of the leading places in the pathology of the visual system of children. According to data obtained from 26 regions of Russia, the leading place in the ocular morbidity of children and adolescents is occupied by ametropia and strabismus with amblyopia. They account for up to 90 % of all cases of visual impairment in childhood. The term amblyopia is understood to mean a decrease in the maximum corrected visual acuity that occurred at an early age, which is caused by disorders of the functions of the visual analyzer, without changes in the fundus and organic lesions of the visual pathways and centers. Despite the outstanding achievements of 21st century medicine, today the questions of the pathophysiological essence of this condition remain open, which is the subject of discussions among pediatric ophthalmologists around the world. In this regard, the literature review presents the results of domestic and foreign authors who studied the morphological (optical coherence tomography) and functional (electroretinography, microperimetry) features of the retina in dysbinocular and anisometropic amblyopia. Some authors have demonstrated the presence of differences in the thickness of the central region and the layer of nerve fibers in patients with amblyopia compared with paired and healthy eyes, their correlation with functional parameters, as well as changes in the thickness of the choroid and microvasculature of the retina. Recently, there have been works devoted to the study of the photosensitivity of the retina in patients with amblyopia and visual rehabilitation using this equipment. A number of authors have shown that with amblyopia, the retinal photosensitivity parameters in the central region are reduced, and there is a correlation between these changes and morphological changes in the posterior pole. The microperimeter also makes it possible to carry out visual rehabilitation, in particular in pediatric patients, and isolated results have been published on the use of this method in patients with amblyopia. The literature data are quite contradictory, and more research remains to be done to determine whether these changes in the retina are primary in relation to this disease, or whether they can be the result of retrograde changes that are obscured by defocusing of visual images from birth.
Transscleral Fixation of the Dislocated IOL-Capsular Bag Complex in Contraction Capsular Syndrome
Authors: Ivanov D. I. , Nikitin V. N.
Published: April 2022

Contraction capsule syndrome is a serious complication accompanied by structural changes of the capsule bag. Fibrous changes of the lens capsule are found in the postoperative period, even in cases of uncomplicated primary cataract surgery. A certain influence has both general systemic state of the patient and local predisposing factors: the presence of pseudoexfoliative syndrome, the material and design of IOL, the size and shape of the anterior capsulorexis. The far-reaching pathological process leads to pronounced anatomical disorders. Excessive, asymmetrical fibrosis of the anterior capsule in combination with the capsulorexis phimosis leads to IOL decentration and frontal inclination, as well as to the dislocation of the entire IOL capsule complex due to local defects of the zinc ligament. The article presents the method of transscleral-suture fixation of the dislocated IOL-Capsular bag complex developed as a result of contraction capsule syndrome on clinical examples. Its distinctive advantages are described. Reduction of invasiveness is achieved due to the “one puncture” technique — ab externo, needle 30G. The proposed method is technically simple and reliable due to absence of conjunctiva peritomy, low probability of polypropylene 9-0 biodegradation, and possibility of its application with different IOL models allows to speak about its universality.
Intraocular Lenses Optic Power Calculation in Extremely Short Eyes
Authors: Pershin К. B. , Pashinova N. F. , Likh I. A. , Tsygankov А. Yu. , Legkikh S. L.
Published: April 2022

Purpose: to choose the optimal formula for calculating the IOL optical power in patients with an axial eye length of less than 20 mm.

Patients and methods. A total of 78 patients (118 eyes) were included in the prospective study. Group I included 30 patients (52 eyes) with extremely short eyes (average axial eye length of 19.60 ± 0.42 (18.54–20.00) mm), group II consisted of 48 patients (66 eyes) with a normal axial length 22.75 ± 0.46 (22.00–23.77) mm with implantation of various monofocal IOL models. The average follow-up period was 13 months. IOL optical power was calculated using the SRK / T formula, retrospective comparison — according to the formulas Hoffer-Q, Holladay II, Olsen, Haigis and Barrett Universal II.

Results. In group I, the maximum average estimation error was determined for the formula Haigis (0.88 ± 0.35), then for the formula Olsen, Barrett Universal II, Kane, SRK / T, Holladay 2 and Hoffer-Q (0.51 ± 0.12, 0.16 ± 0.38, 0.13 ± 0.28, 0.10 ± 0.59, 0.05 ± 0.54 and –0.12 ± 0.42, respectively). Similar data were obtained for the average absolute error — for the formulas Haigis, Olsen, Barrett Universal II, SRK / T, Holladay 2, Hoffer-Q and Kane, it was 0.85 ± 0.31, 0.78 ± 0.25, 0.21 ± 0.10, 0.79 ± 0.23, 0.73 ± 0.24, 0.19 ± 0.08 and 0.17 ± 0.06, respectively. When comparing the formulas, significant differences were found for the formulas Hoffer-Q, Barrett Universal II and Kane in comparison with the formulas Haigis, Olsen, SRK / T and Holladay II (p < 0.05) in all cases, respectively, which indicates the advantage of these formulas for the group patients with extremely short eyes. In group II, there were no significant differences between the studied formulas (p > 0.05).

Conclusion. This paper presents an analysis of our own data on the effectiveness of six formulas for calculating the IOL optical power in extremely short (less than 20 mm) eyes in comparison with the normal axial length. The advantage of the Hoffer-Q, Barrett Universal II and Kane formulas over Haigis, Holladay 2, Olsen, and SRK / T is shown. To determine the exact indications for using these formulas, further studies are necessary taking into account the anterior chamber depth and a lesser degree of hyperopia.
Immediately Sequential Bilateral Cataract Surgery: the Opinion of Russian Ophthalmologists
Authors: Pokrovsky D. F. , Medvedev I. B.
Published: April 2022

Purpose. A study of the attitude of Russian ophthalmologists to Immediately Sequential Bilateral Cataract Surgery (ISBCS).

Methods. The study was carried out with the participation of 184 ophthalmologists actively performing cataract surgery, who were presented (in personal contact or via the Internet) a questionnaire developed by the authors, based on three main sections (“I use ISBCS in practice”; “I do not use ISBCS in practice”; “I don’t use, but I did ISBCS before”), which includes in each of the sections a number of clarifying questions and possible answers (“Doesn’t matter”; “Matters”; “Important”; “Very important”). At the same time, the analysis of possible answers was carried out by summing up two possible options — “Negative” opinion (“Not important” + “Matters”) and “Positive opinion” (“Important” + “Very important”). The age of the interviewed ranged from 26 to 58 years (mean age 36.2 ± 1.9 years), the experience of surgical activity in performing cataract phacoemulsification was predominantly (76 %) more than 5 years.

Results. The data obtained indicate that 36 respondents (19.8 %) use ISBCS in their practice, 114 (61.8 %) do not use ISBCS; 34 (18.4 %) — do not use, but previously used ISBCS. At the same time, the volume of ISBCS performed on the same day is (for 84 % of respondents) no more than 20 % of the total number of operations performed. As part of the assessment of the main factors, in accordance with which (according to the ophthalmic surgeon), the patient is offered to perform ISBCS by the leader (in terms of the ratio of “positive” and “negative” opinions) is less clinic visits, and less time spent for the patient. The leading reasons for refusal to perform ISBCS by ophthalmic surgeons who do not use this technology are the possible occurrence of endophthalmitis, the risk of errors in IOL calculation, and medical and legal problems.

Conclusion. The conducted questioning of domestic ophthalmologists testifies to the low prevalence of ISBCS technology, which is mainly associated with the possible risks of postoperative infectious complications, the lack of a standard protocol for surgical intervention, as well as medical and legal aspects. For the wider use of ISBCS, especially in a difficult epidemiological situation, it is necessary to carry out a set of measures of medical, educational and medical and economic orientation.
Clinico-bacteriological profile and antibiogram of Staphylococcus epidermidis with special emphasis on Methicillin resistance and hospital acquired infections in a tertiary care center south India
Authors: Nandihal Namratha W , Chikkaraddi Uma
Published: April 2022

is a normal commensal of the skin and mucous membrane of humans and animals. Despite the growing importance of its pathogenesis especially in neonatal septicemia and device associated infections, it is still considered as insignificant isolate in the clinical practice. Hence, the present study is taken up to analyze the sources and risk factors of the isolates and to know their antibiogram along with occurrence of Methicillin resistant (MRSE).

150 clinically significant isolates from various clinical specimens were considered in this study. Species identification was done by phenotypic methods. The antimicrobial susceptibility test and detection of Methicillin resistance were performed by Kirby-Bauer's disc diffusion method as per CLSI guidelines.

Among 150 isolates, 78% were recovered from hospital acquired infections. They were commonly isolated in pediatric age group (30%) and among males (60.67%). Total of 34.67% were isolated from pus samples followed by blood (25.33%). Most of the isolates were associated with multiple risk factors like hospitalization, prior antibiotic administration, foreign body in situ and ICU admission. Majority of the isolates expressed resistance towards Penicillin (93.33%), followed by Amoxicillin-Clavulanic acid (76%), Cotrimoxazole (71.33%), Fluoroquinolones (64%), Gentamicin (60%) and Erythromycin (55.33%). Resistance against Amikacin (16.67%), Tetracycline (9.3%) and Linezolid (0.67%) was low. All isolates were sensitive to Vancomycin. Inducible Clindamycin resistance was 18% and MRSE was 68%.

: Clinical importance and emergence of drug resistance among infections is growing with the advent of advanced medicine. This warrants the need to implement simple laboratory methods for species identification of the and to determine the antibiotic resistant patterns on routine basis. Clinical correlation of the isolate is crucial to rule out the colonizers and contaminants.
Seroprevalence and changing trend of dengue in a tertiary care hospital, Bhubaneswar, Odisha: Four-year retrospective study
Authors: Pathi Basanti Kumari , Poddar Nirmala , Panigrahi Kumudini , Pattnaik Dipti , Jena Jagadananda
Published: April 2022

Dengue virus is a single stranded positive sense RNA virus belonging to the genus flavivirus family flaviviridae. Dengue fever is a seasonal and emerging acute mosquito borne arbo-viral illness affecting tropical and sub-tropical countries. This illness ranges from a mild asymptomatic form to severe dengue hemorrhagic fever (DHF) with or without dengue shock syndrome (DSS).

This study was conducted to know the seroprevalence and changing trend of Dengue virus in a tertiary care hospital, Bhubaneswar, Odisha, India.

Over a period of four years from August 2016 to December 2019, a total of 5147 blood samples from clinically suspected dengue patients were received in department of Microbiology laboratory. Serum was separated and subjected to enzyme immunoassay for detection of both Non Structural (NS1) antigen and IgM antibody.

During this study period, a total of 5147 blood samples were processed from suspected dengue cases, out of which 1314(25%) samples were found to be positive by different serological markers like NS1 Antigen (Ag), IgM antibody(Ab), or both NS1 Ag & IgM Ab. The overall seroprevalence rate was found to be 25%. In this study period of four years, the year-wise seroprevalence rate was found to be 12% (153) in the year 2016 and was 26% (350) in the year 2017 and was 40% (522) in the year 2018, and was 22% (289) in the year 2019. It clearly shows that there is an increase in the dengue cases.
Bacteriological profile and antibiogram analysis from a tertiary care centre in eastern India: Time to Act / ReAct
Authors: Sharma Raj Kishor , Singh Asim , Ranjan Manish , Singh Mukesh Kumar
Published: April 2022

Development of antimicrobial resistance imposes a serious threat to the timely and efficient healing of mankind who fall prey to the infectious agents. It is increasingly being reported day by day throughout the world. Irrational and overuse of antibiotics coupled with unavailability of regional or local antibiogram aggravates the situation further.

To understand and present the local antbiogram data for this region and bridge the existing knowledge gap about the same for this particular region.

Two year data was retrospectively analyzed from a 750 bedded tertiary care centre.

A total of 1143 non repeat isolates were studied, their antibiogram profiles were analyzed. Percentage of Gram negative bacteria obtained were 59.6%, while Gram Positive bacteria were obtained in 40.4% of the isolates. (22.8%) was the most common organism isolated, followed by Staphylococcus aureus (14.2%), Other sp(12.8%), sp(12.6%), (9.4%), and complex(7.4%), Miscellaneous Bacteria(13.4%). An alarming number of isolates were found to be Multidrug resistant isolates(MDRs). With the panel of antibiotics tested for Gram negative bacterial isolates, only Fosfomycin(1.5%), Nitrofurantoin(16%) & Chloramphenicol (19%) were the only antibiotics to exhibit <20% resistance. Antibiotics for Gram positive bacteria for which low resistance was observed were Vancomycin (0%), Linezolid (0.1%), Teicoplanin (<1%), Aminoglycosides (18%), Nitrofurantoin(15%), Chloramphenicol(6%) & Tetracyclines(11%). Extended Spectrum Beta lactamase(ESBL) prevalence was estimated to be 63.6% in , 82.4% in Klebsiellapneumoniae. Methicillin resistant Staphylococcus aureus (MRSA) was seen in 54% of the isolates, while Inducible clindamycin resistance was observed in 35.9% of the isolates.

It is high time that we shift our focus from internationally and nationally available data on antibiogram to locally prevalent antibiotic resistance pattern. It will ensure faster patient recovery at a lesser cost and also prevent undue development of drug resistance.
O Ensino de Ciências da Natureza nas versões da Base Nacional Comum Curricular (BNCC)
Authors: Mattos Kélli Renata Corrêa de , Amestoy Micheli Bordoli , Tolentino-Neto Luiz Caldeira Brant de
Published: April 2022

Este artigo aborda o contexto de elaboração da Base Nacional Comum Curricular (BNCC) e algumas das reverberações na área de Ciências da Natureza (CN), fomentando uma discussão sobre políticas educacionais no cenário contemporâneo do ensino de CN. Sendo assim, o presente estudo tem como objetivo analisar a proposta do componente curricular de CN, ao longo das cinco versões da BNCC, com a perspectiva de compreender como a recente reforma educacional foi elaborada e quais as ideologias e interesses que se fazem presentes. Trata-se de uma pesquisa de cunho qualitativo e pautada em uma análise documental. A partir da análise realizada, observa-se que o ensino de CN sofreu impactos com os impasses vivenciados no contexto político-social brasileiro, ao longo da construção da Base. Ademais, percebe-se a descaracterização de temas relevantes à formação humana e pertinentes à área de CN, como: Educação Ambiental e Sexualidade. Contudo, mesmo diante da notável impotência da comunidade escolar frente à BNCC, permanecem os esforços em fomentar uma análise crítica ao documento, de modo a empoderar professores e professoras a desenvolver aulas com temáticas e abordagens descaracterizadas na Base.
Quimiguia: desenvolvimento e validação de um aplicativo de apoio ao processo de ensino-aprendizagem de química no ensino superior
Authors: Rosa Anderson Silva , Santos Paola Aquino , Jardim Anderson Luis Salazart , Gonçalves Raul Calixto , Miotto Haline Silva , Roehrs Rafael
Published: April 2022

Esta pesquisa apresenta o desenvolvimento e a validação do aplicativo Quimiguia. O App Quimiguia é um aplicativo para dispositivos móveis desenvolvido com o objetivo de ser uma ferramenta de apoio ao processo de ensino-aprendizagem de conceitos relacionados à química para discentes de cursos de graduação, que possuem componentes curriculares relacionados à química em sua grade curricular. O App foi desenvolvido e validado junto a especialistas e graduandos que o avaliaram quanto a aspectos técnicos e pedagógicos. Durante a validação, os estudantes também resolveram problemas de química, com auxílio do aplicativo, atingindo um percentual médio de 78% de acertos por questão. Especialistas e graduandos avaliaram positivamente o aplicativo quanto a todos os aspectos avaliados e consideraram o App Quimiguia uma ferramenta que pode contribuir no processo de ensino-aprendizagem de conceitos relacionados à química no Ensino Superior, podendo ser utilizado para consulta, revisão e/ou reforço de conceitos básicos.
O Lógos Filosófico e o Lógos Poético: ao doce mago da floresta amazônica
Authors: Giacoia Júnior Oswaldo
Published: April 2022

Entre nós, o filósofo Benedito Nunes talvez tenha sido um dos primeiros a remeter o pensamento sobre as perguntas, os desafios, a desorientação, que emerge da crise da razão em suas dimensões práticas e especulativas, à necessidade de reflexão profunda sobre a experiência do tempo, que corresponde à modernidade - um tempo histórico do qual, como pretendia Kant, a Aufklärung se constitui num signo diagnóstico, rememorativo e prospectivo. E uma vez que o historicismo integra essencialmente o programa crítico da Aufklärung, também ele contribuiu de maneira decisiva para a formação da moderna consciência histórica. Este artigo pretende continuar nessas sendas abertas por Benedito Nunes para se interrogar, a partir de Heidegger, acerca das relações entre o logos filosófico e o logos poético.
O terrível limite da palavra: um encontro entre Benedito Nunes, Vilém Flusser e Clarice Lispector
Authors: Duarte Rodrigo Antônio Da Paiva
Published: April 2022

O consagrado livro de Benedito Nunes sobre Clarice Lispector, cuja versão definitiva (e expandida) foi publicada em 1989, teve duas edições anteriores: a primeira publicada em 1966, com o título de O mundo de Clarice Lispector, e a segunda em 1973, intitulada Uma leitura de Clarice Lispector. A primeira versão, de 1966 chamou a atenção do filósofo Vilém Flusser, que escreveu e publicou no Suplemento Literário do Estado de São Paulo, em sua edição de 25/06/1966, uma entusiasmada resenha sobre o livro, na qual transparece o reconhecimento, por Flusser, de sua tese da proximidade possível entre a filosofia analítica da linguagem e o pensamento existencial. Nessa resenha, o filósofo tcheco-brasileiro avalia a contribuição de Nunes e de Lispector importante em nível mundial, declarando a necessidade de que a obra do filósofo belenense fosse traduzida para outros idiomas, de modo a alcançar um público mais amplo.
Benedito Nunes, leitor de Oswald de Andrade
Authors: Kangussu Imaculada
Published: April 2022

O artigo apresenta algumas das reflexões de Benedito Nunes sobre os, por ele denominados, “escritos doutrinários” de Oswald de Andrade. Dos sete escritos que Benedito Nunes comenta em “Antropofagia ao alcance de todos”, focamos principalmente nas passagens relativas aos dois manifestos poéticos de Oswald de Andrade – “Manifesto da Poesia Pau-Brasil” e “Manifesto Antropófago” – e a “O achado de Vespúcio”.
A Hora de Max Martins: a temporalidade do artista no poema O tempo o homem
Authors: Martins Ricardo Evandro Santos
Published: April 2022

O ensaio tentar realizar um exercício hermenêutico de explicitar os sentidos de tempo que surgem no poema O tempo o homem, do poeta paraense Max Martins. Neste ensaio, as premissas interpretativas partem sobretudo do pensamento do filósofo paraense Benedito Nunes, tendo, no horizonte a Ontologia fundamental de Martin Heidegger, mas também de outros pensadores, como Giorgio Agamben. Além disto, o horizonte hermenêutico deste ensaio alcança um dos poetas que marcaram determinantemente a poesia de Max Marins, que foi seu amigo Mário Faustino. Assim, o problema central desta investigação ensaística é a busca por saber o sentido dos tempos Ampulheta, Era, hera e Hora. A hipótese é que o aporte hermenêutico fenomenológico desenvolvido por Benedito Nunes para a relação dialógica, de “transa”, entre poesia e filosofia, viabilizada pelo que chamou de “passagem para o poético” (Kehre), oferece a tese de que o poema de Max Martins é um poema sobre o próprio poetar e sobre a “aventura” enquanto “evento” (Ereignis) da Hora que o artista faz.
Benedito Nunes: um esteta nos trópicos amazônicos
Authors: Bezerra José Denis De Oliveira
Published: April 2022

Benedito Nunes é uma das maiores referências intelectuais paraenses. Atuou em vários campos da linguagem, sempre no exercício crítico da arte, da literatura e da filosofia. Além dessas áreas de atuação, consolidadas em sua trajetória profissional, trazemos para nossa análise suas reflexões e engajamento com o setor da produção cultural amazônica das décadas de 1950 e 1960, através de textos sobre o contexto sociocultural paraense do período. Além disso, investigamos sua participação como docente no curso de Formação de Ator da Escola de Teatro da Universidade Federal do Pará nos anos 1960 e a relação de sua prática pedagógica no contexto de elaboração de sua teoria filosófica da arte.
Benedito Nunes, estudante de Direito: a formação do filósofo na Faculdade de Direito do Pará (1948-1952)
Authors: Russo Fróes Rodrigues Victor
Published: April 2022

Benedito Nunes, aclamado filósofo e crítico literário, guarda em sua biografia um período de formação jurídica na Faculdade de Direito do Pará, entre os anos de 1948 e 1952. Este é um dado que normalmente fica isolado na observação de sua trajetória, sobretudo em relação aos aspectos intelectuais da formação jurídica, fator que pode permitir uma maior compreensão sobre a construção do pensamento do filósofo. Diante dessa percepção, o presente trabalho tem como objetivo analisar a formação jurídico-filosófica propiciada pela Faculdade de Direito do Pará ao estudante Benedito Nunes, dando ênfase aos estudos realizados em “Introdução à Ciência do Direito”, disciplina ministrada pelo professor Daniel Coelho de Souza. Para tanto, utiliza-se como base os dossiês acadêmicos albergados pelo Arquivo da atual Faculdade de Direito da Universidade Federal do Pará (UFPA) e demais fontes que auxiliam o trabalho a partir da perspectiva da História Intelectual. Em conclusão, nota-se que a Faculdadem de Direito do Pará foi um ambiente que contribuiu para a formação da visão de mundo de seus bacharéis, em especial de Benedito Nunes, por meio da formação filosófica rica em temas de Teoria do Conhecimento, abrindo possibilidades para um pensamento universal.
Uma leitura existencialista de A paixão segundo G.H., de Clarice Lispector
Authors: Paes Lima Anna Clara
Published: April 2022

Realiza-se aqui uma análise da obra literária A Paixão Segundo G.H. (1964), de Clarice Lispector, a partir do viés filosófico existencialista, desenvolvido por Jean-Paul Sartre em sua obra O Ser e o Nada: Ensaio de Ontologia Fenomenológico (1943). Assim sendo, a obra que será objeto de estudo acompanha a jornada existencial da personagem G.H. em busca de sua própria identidade. Nesse sentido, utiliza-se aqui a teoria existencialista ateísta de Sartre, assim como o estudo realizado pelo filósofo paraense, Benedito Nunes, que buscou averiguar toda a filosofia metafísica no conjunto da obra de Clarice Lispector, em seu livro Leitura de Clarice Lispector (1973) e o Drama da Linguagem: uma leitura de Clarice Lispector (1989). Por fim, o presente texto tem como objetivo averiguar as atitudes de má-fé executadas pela personagem, analisar a Angústia que intercala com sua Náusea existencial, expressados pela linguagem única de Lispector.
A Transformerless Common-Ground Two-Switch Single-Phase Inverter for Battery Energy Storage System Applications
Authors: Assunção Gabriel de O. , Barbi Ivo
Published: April 2022

This paper proposes a transformerless common-ground single-phase inverter for battery energy storage system (BESS) applications. With regard to conventional converters operating as a voltage source inverter (VSI), the proposed converter offers the advantage of a common connection between the battery bank negative terminal and the ground. Hence, the common-mode voltage becomes continuous while common-mode currents flowing through parasitic capacitances located between the battery bank and the grounded metallic frame are eliminated, allowing operation without a transformer. This new topology has only two power semiconductors, two inductors and one capacitor, without the need for a filter on the AC grid side. The converter operation is described and the relevant equations for sizing are presented along with the main characteristics. A 1 kW non-optimized prototype was dimensioned, built and tested to validate in practice the theoretical analysis, and a maximum efficiency of 95.25% was obtained. Due to the simplicity, low number of active components, no clamping circuit requirement and the common-ground, this topology is a very interesting option for the above-mentioned application.
Selection of self-compatible progenies of high productivity cocoa in the Ecuadorian coast
Authors: Quinaluisa Morán César , Navarrete Schettini Gabriel , Franco Ochoa Diego , Bustamante González Antonio Javier , Sotomayor Cantos Ignacio , Mehdi Jazayeri Seyed
Published: April 2022

Cocoa in Ecuador is one of the main crops of economic importance, mainly for small and medium farmers on the coast. Sexual self-compatibility is one of the most important criteria for the selection of clonal plants from members of hybrid progeny. Trees with higher levels of self-compatibility are those that tend to produce earlier compared to self-compatible ones. The study consisted of selecting 333 trees from a group of 71 hybrid progenies, based on selection criteria such as productivity and health during 5 years of evaluation (2002-2007) and thus determining the level of self-compatibility per individual within a group of hybrid progenies. of cocoa, estimate the level of self-compatibility of the hybrid progeny under study and its relationship with yield and select self-compatible trees with high productivity. Binomial test was used, which determined a minimum of 30% of successful pollinations. The 0.05% probability level was considered as the compatibility threshold of each tree. For hybrid progenies, at least 70% of their individuals must present this characteristic, for which data were recorded at three, seven and fifteen days respectively, in order to have more precision in the process of fruit initial development and performance. The results showed that there was a wide variability regarding the self-compatibility level of the individuals within all the studied families. Only 3 of 71 studied families had a sufficient number of self-compatible individuals to be classified likewise. However, their average performance was not necessarily superior to other families that were self-compatible. On the other hand, it could also be confirmed that the compatibility of a tree, clone or cross can change its percentage of fertilization according to time and environmental conditions.
Microalgas en el tratamiento de aguas residuales generadas en industrias de curtiembres
Authors: Jácome-Pilco Carlos , Ballesteros Carlos , Rea Edwin , Rea Cayambe Luz Margarita
Published: April 2022

Las aguas residuales provenientes de la industria de curtiembre, presentan elevadas concentraciones de metales pesados, especialmente de cromo (Cr), así como también, de otros componentes como Nitritos, Nitratos, Fosfatos, Sulfatos, que de no ser tratados previa a su descarga puede alterar gravemente la calidad de los cuerpos de agua superficiales. De manera que, un tratamiento alternativo a estos efluentes industriales, se ha venido proponiendo en diversas investigaciones. En tal sentido, el objetivo de este trabajo fue realizar una revisión bibliográfica detallada sobre la utilización de microalgas para tratar aguas residuales procedentes de curtiembres. Para lo cual, se analizaron 42 trabajos de entre artículo científicos y tesis con index internacional todos ellos relacionados al tema de trabajo. Tras el análisis, las microalgas más utilizadas en los procesos de biorremediación en este tipo de industria son: Scenedesmus sp, Espirulina sp, Chlorella sp, Tetraselmis sp, y Pseudochlorella sp., importantes por su alta eficiencia en la remoción de Cromo, y otros elementos contaminantes; donde, los géneros Scenedesmus y Espirulina demostraron una eficiencia mayor al 85% de remoción de Cr, seguido por Chlorella y Pseudochlorella (>60%). En la remoción de nitratos y nitritos, el género Scenedesmus, mostró mejores niveles de remoción (90%), seguido por Chlorella y Pseudochlorella (65%). Con respecto a la remoción de Fostatos y Sulfatos, los géneros Chlorella y Pseudochlorella fueron el tipo de alga que demostró un nivel de remoción del 100%, seguidos por Tetraselmis, Scenedesmus y Tetraselmis (>95%). Este consorcio de micro algas podrían ser buenas alternativas a los métodos de tratamiento convencionales para la industria del cuero.
Time Evolution of External Shocks on Macroeconomic Fluctuations in Pacific Alliance Countries: Empirical Application using TVP-VAR-SV Models
Authors: Rodríguez Gabriel , Vassallo Renato
Published: April 2022

Este artículo proporciona evidencia empírica sobre la evolución del impacto de los choques externos en la dinámica macroeconómica de los países de la Alianza del Pacífico (AP). Para ello estimamos una familia de modelos VAR que permite la variación (o constancia) temporal de los parámetros, incluyendo la matriz de varianzas (TVP-VAR-SV). Los resultados sugieren que: (i) las fluctuaciones de China crean las respuestas más significativas y persistentes: un aumento del 1% en el crecimiento de China aumenta el crecimiento en un 0.3%-0.4% durante el primer año en Chile, Colombia y México; y un 0.8% en Perú; (ii) las respuestas a los choques de precios de exportación evolucionan considerablemente con el tiempo; por ejemplo, el impacto sobre el crecimiento en Chile y Perú se triplicó en 1994-2009 y luego se moderó hasta 2019; y (iii) los aumentos inesperados de la tasa de la Fed dan como resultado aumentos significativos en las tasas de política monetaria de los países AP, un efecto que aumenta durante los períodos de crisis y profundiza aún más el impacto negativo en el crecimiento de la producción interna. Adicionalmente, la descomposición de la varianza muestra que los factores externos explican más del 50% de las desviaciones en las variables domésticas consideradas en este trabajo. En particular, los resultados muestran que la absorción de choques externos sobre la muestra es mayor en México y Perú. En contraste, el cambio en la dinámica interna en ausencia de perturbaciones externas hubiera sido más leve en Chile y Colombia. Finalmente, realizamos cuatro ejercicios de robustez, que implican las siguientes modificaciones al modelo de base: (i) cambio de priors; (ii) modificación de dos variables externas; (iii) uso de modelos de menor dimensión (4, 5 y 6 variables); y (iv) ampliar el modelo agregando una variable de política fiscal. Los resultados no cambian significativamente en relación con los encontrados utilizando el modelo de referencia.
Time Changing Effects of External Shocks on Macroeconomic Fluctuations in Peru: Empirical Application Using Regime-Switching VAR Models with Stochastic Volatility Paulo Chávez y Gabriel Rodríguez
Authors: Rodríguez Gabriel , Chávez Paulo
Published: April 2022

Este artículo cuantifica y analiza la evolución del impacto de los choques externos en las fluctuaciones macroeconómicas del Perú en 1994Q1-2019Q4. Para este propósito, usamos un grupo de modelos de vectores autoregresivos con parámetros con cambio de regimen y volatilidad estocástica (RS-VAR-SV), según lo propuesto por Chan y Eisenstat (2018). Los datos sugieren la preferencia por un modelo con coeficientes contemporáneos y rezagos e intercepciones constantes, pero con varianzas dependientes del regimen; y se observa la existencia de dos regímenes. Las IRFs, FEVDs y HDs muestran que: (i) los choques de crecimiento de China tienen un mayor impacto en el crecimiento de la producción de Perú (alrededor del 0.8%); (ii) los choques financierios contraen el crecimiento de la producción interna en un 0.3% y la política monetaria doméstica se sincroniza con movimientos de la tasa de la Reserva Federal; (iii) los choques externos explican el 35% y el 70% de las fluctuaciones del producto en los regímenes 1 y 2, respectivamente; y (iv) los choques de crecimiento de China contribuyen con 1.0 p.p. de 1.1-p.p. (alrededor del 89%) del crecimiento de la producción de Perú entre los regímenes 1 y 2. Los resultados son validados utilizando siete ejercicios de robustez que consisten en cambiar las priors, reordenar las variables, cambiar las variables y usar cuatro especificaciones diferentes para el modelo de base.
Consideraciones sobre el desarrollo y sobre las perspectivas de la linguística
Authors: Baldinger Kurt
Published: April 2022

No contiene resumen
Para una nueva lectura de Doña Perfecta de Galdós
Authors: Lerner Isaías
Published: April 2022

No contiene resumen
Definiciones y clasificaciones en la lengua natural : doxología y configuración sémica
Authors: Campodónico Carrión Hermis
Published: April 2022

Este artículo no presenta resúmen
Metáfora, literalidad, transgresión: amor-muerte en la celestina y en la égloga II de Garcilaso
Authors: Azar Inés
Published: April 2022

No presenta resúmen
Relaciones entre lo teórico y lo empírico en la dialectología
Authors: Heger Klaus
Published: April 2022

No presenta resúmen
Hacia una tipología del texto narrativo en las lenguas indígenas del Perú
Authors: Wise Mary Ruth
Published: April 2022

No presenta resúmen
De re y de dicto : sobre la sintaxis y la semántica de la necesidad esencial
Authors: Secada Jorge E.
Published: April 2022

El artículo no presenta resumen.
Un aspecto del quechua de Ancash
Authors: Weber David J.
Published: April 2022

El artículo no presenta resumen.
Genetic Variability, Correlation and Path Analysis in Cowpea [Vigna unguiculata (L.) Walp]
Authors: Gupta Sheetal , Intwala C.G. , Ganesh S. Sree
Published: April 2022

Background: Cowpea [Vigna unguiculata (L.) Walp] is a self pollinated crop, belonging to family fabaceae and sub family papilionaceae. It is an important multipurpose grain legume extensively cultivated in arid and semi arid regions of Sub-Saharan Africa, Asia, Central and South America. The assessment of variability present in any crop species is an essential pre requisite for formulating an effective breeding programme, as the existing variability can be used to enhance the yield level of cultivars after following appropriate breeding strategies. Methods: The present investigation was carried out during the Kharif season of the year 2019. The field experiment was carried out at Pulses Research Station, NAU, Navsari in randomized block design. The study was undertaken on fifty three genotypes of cowpea to know the variability present among genotypes for thirteen traits and correlation and path analysis of yield components. Result: Analysis of variance indicated significant genotypic differences for all the characters under study. The highest GCV was recorded for plant height, pods per plant, pods per cluster, seed yield per plant, straw yield per plant, 100 seed weight and harvest index. High heritability coupled with high genetic advance was exhibited by days to 50 per cent flowering, days to maturity, plant weight, seed yield per plant, 100 seed weight, pod length, pods per cluster and seeds per pod indicating the presence of additive gene action. Seed yield per plant was found to be positively and significantly correlated with pods per plant, pods per cluster, pod length, days to 50 per cent flowering and straw yield per plant or seed yield per plant. The present study has indicated the need for giving due weightage to pods per plant, pods per cluster, seeds per pod, 100 seed weight, pod length with straw yield per plant for improving seed yield in cowpea.