bluuebunny/crossref_metadata_2025 huggingface dataset:
Hairpin impacted in the duodenum of a 4-month-old child - a rarity
Authors: Rattan Kamal Nain , - Priyadarashani , Baridabad Omkarmanik , Yadav Kuldeep Kumar , Chopra Bhavna
Published: June 2020

Foreign body ingestion is common in children. The accidental ingestion is usually seen in children due to lingual curiosity. Most of the foreign body passes spontaneously through gastrointestinal (GI) tract; hence, requiring no removal. This is a case of impacted hairpin in the duodenum of a 4-month-old female child who accidentally ingested hairpin and was asymptomatic initially for 1 month and later presented with melena requiring surgical removal of hairpin. We failed to find in literature impacted hairpin in the duodenum associated with GI bleeding.
“I Still Support My Favorite Team”: The Effects of an Athlete’s Transgression and Post-Response Strategy Using Visual Cues on In-Group Bias
Authors: Jang Wonseok (Eric) , Lee Joon Sung , Cho Janice , Lee Jeoung-Hak
Published: June 2020

Abstract: Using an in-group bias effect as a theoretical framework, this study examined how scandal-ridden athletes may obtain forgiveness and continuous support from highly identified sport consumers depending on the visual strategy used in the official statement and the severity of the scandal. The results indicated that for a high-severity scandal, an angular shape is more effective than a circular shape in eliciting positive evaluations from highly identified sport consumers. In contrast, for a low-severity scandal, a circular shape is more effective than an angular shape in obtaining positive evaluations from highly identified sport consumers. The underlying mechanism is that each type of visual shape is associated with different types of perception (softness vs. hardness), and the in-group bias effect occurred only when the perception of the visual shape matched the severity of the scandal.
Educação em tempo integral: Um breve panorama
Authors: Dias Kátia Gonçalves
Published: June 2020

A educação integral é uma importante peça da história da cidadania, logo, do homem, e, dessa forma, é uma temática que tem sido profundamente discutida e os seus conceitos reelaborados ao longo dos anos. Essa proposta tem como objetivo discutir e refletir, a partir de uma revisão da literatura, sobre o Programa Educação em Tempo Integral. Trata-se de um estudo bibliográfico e descritivo. Parte-se da hipótese de que para que a educação seja, de fato integral, apenas aumentar o tempo de permanência na escola não acarreta a formação integral. Considerando esse contexto, o artigo versará sobre os caminhos percorridos pela educação integral, tendo como enfoque o referido programa. Tem se como problema de pesquisa o fato de que a educação integral, ainda hoje, mesmo que tenha se popularizado, é um desafio para o país, devido à falta de recursos e de capacitação dos professores na maioria das escolas, o que justifica a relevância do estudo. Serão apresentadas as políticas públicas sobre a temática e como essa proposta tem se consolidado no Brasil.
Análise do processo de escavação de túneis pela ótica do New Austrian Tunneling Method – NATM
Authors: Estanqueiro Lucas de Araujo , Salvi Levi
Published: June 2020

A escolha do método para escavação de túneis é determinada pelo projeto de traçado e pelo tipo de solo ou rocha encontrados em cada região. No entanto, o método de escavação está ligado diretamente a velocidade desejada para execução do serviço e ao tipo de solo. Esses dois fatores regem o estudo de viabilidade, porque o método mais rápido dificilmente será o mais econômico e sustentável. A escolha equivocada do método poderá acarretar uma manutenção mais onerosa para o projeto na sua totalidade, que engloba a execução, acabamento e manutenção. Este artigo avaliou e compilou as características do “New Austrian Tunneling Method” (NATM), tal como suas etapas de execução e aplicação prática, resultando em uma análise que demonstra ser uma alternativa eficiente, sustentável e economicamente viável na construção de túneis, primordialmente rodoviários e ferroviários, posto que o cenário nacional tem grande potencial de crescimento no segmento de infraestrutura de transporte.
The unconscious knowledge of the subject and the desire of the analyst in the drug clinic
Authors: Rocha Lorena Fabiani da
Published: June 2020

The clinical care to drug patients requires that unconscious dimensions of the subject who drugs and the accompanying analyst be observed, considering that these dimensions precede and imply the patient’s condition of dependence. Thus, this work aims to clarify psychoanalytic perspectives that guide the approach of the toxicomanphenomenon in the setting of care. Concepts such as “unconscious” and “analyst desire” were taken in order to elucidate how the analytical situation constitutes an individualizing treatment and is opposed to the classical psychiatry method. Therefore, it is emphasized the existence of a particular knowledge in each patient about his drug addiction, which was not predicted by medical nosology. Therefore, the psychiatric technique is considered insufficient and an approach is explored that seeks to better interpret drug addiction, having as a tool to base the analyst’s desire. In addition to the central concepts brought by the title, the work also goes through the notions of “language”, “malaise in culture”, “I”, “monomania”, “castration” and “drive maturation”. The research started from the bibliographical investigation method, referring to the theme “Drug addiction” in the scope of Psychoanalysis and classical psychiatry. The literature of consecrated authors who cross-trust such knowledge, such as Freud, Lacan and Bercherie, was used.
High doses of melatonin as a potential therapeutic tool for the neurologic sequels of covid-19 infection
Authors: Cardinali Daniel Pedro
Published: June 2020

The therapeutic potential of melatonin as an agent to counteract the consequences of COVID-19 infections is due to its wide-ranging effects as a powerful antioxidant, anti-inflammatory, and immunostimulant, as well as to a possible antiviral action. In view of the recently reported evidence on the occurrence of neurological sequels in COVID-19-infected patients, another putative application of melatonin emerges based on its neuroprotective properties. In this manuscript a brief discussion of melatonin activity in animal models of ischemic and hemorrhagic stroke and the allometric calculations of the possible human equivalent doses are made. Based on the safety of melatonin, and in order to maximize its therapeutic opportunity, doses of 100 - 300 mg p.o. or i.v.  are proposed.
Melatonin, cardiovascular disease and COVID-19: A potential therapeutic strategy?
Authors: Dominguez-Rodriguez Alberto , Abreu-Gonzalez Pedro , Marik Paul E , Reiter Russel J
Published: June 2020

The mechanism for SARS-CoV-2 infection is the requisite binding of the virus to the membrane-bound form of angiotensin-converting enzyme 2 (ACE2) and internalization of the complex by the host cell. SARS-CoV-2 induced endothelial dysfunction and cardiovascular injury are probably initiated by increases in the phosphorylation levels of JAK2 and STAT3 and resultant reactive oxygen species (ROS) formation. These pathological alterations are speculated to be strikingly reversed by melatonin
The potential of melatonin in the prevention and attenuation of oxidative hemolysis and myocardial injury from cd147 SARS-CoV-2 spike protein receptor binding
Authors: Loh Doris
Published: June 2020

The rapid escalation of pandemic health threats associated with the novel, pathogenic SARS-CoV-2 coronavirus poses unprecedented challenges as proven effective vaccines and drugs have yet to be produced. Refractory hypoxemia and myocardial injury have been observed as two of the major causes of fatality in COVID-19 patients. SARS-CoV-2 spike (S) protein binding to broadly expressed CD147 receptors on erythrocytes causes oxidative hemolysis that may result in refractory hypoxemia and myocardial injury. Both of these life-threatening conditions are further exacerbated by imbalance in ACE2 from spike (S) protein receptor binding. Dysregulation in the CD147-cyclophilin A signaling pathway, together with altered calcium signaling from SARS-CoV-2 ion channel activities, may contribute to hypercoagulation, thrombosis, and cardiac remodeling resulting in heart failure. Melatonin is an ancient pleiotropic molecule with recognized antioxidant properties that is essential for the protection of erythrocytes from oxidative hemolysis. Found in erythrocytes, melatonin can reverse hemolytic anemia, normalize heme synthesis, restore lymphocytes and platelet counts, and reduce vessel permeability during an acute hemolytic crisis by maintaining intracellular calcium homeostasis and reduction of oxidative stress. In acute hypoxic conditions, melatonin is cardioprotective via blunting of cardiopulmonary response to hypoxia and suppressing hypoxia pathways. Melatonin normalizes endothelial-dependent nitric oxide production to prevent multiple organ damage from hypercoagulability, thrombosis, and hypertension associated with oxidative hemolysis and ACE2 deficiency, protecting cardiomyocytes from hypertrophy. This review discusses the full potential of melatonin as a safe and effective therapeutic intervention for the prevention and attenuation of hemoglobinopathies, refractory hypoxemia and myocardial injury during critical COVID-19 infections.
Analyzing Factors of Hybrid Electric Vehicle Adoption Using Total Cost of Ownership
Authors: Lee Joosung , Kwon Yeongmin
Published: June 2020

Around 20% of total greenhouse gas emissions occur in transportation, 85% of which takes place in road traffics. Environmentally friendly vehicles are a transport type which has less environment impacts compared to existing internal combustion engine vehicles. Among them hybrid electric vehicles (HEVs) have increased steadily in South Korea. This paper analyzes the sales of YF SONATA HEV and K5 HEV, which account for 85% of the domestic HEV market, compared to gasoline engine versions of the same models from Total Cost of Ownership (TCO) viewpoint. The relationship between the vehicle’s TCO and HEV sales share were analyzed as well as the consumer’s perception about the value associated with purchasing HEVs. This research conducts a quantitative study on the necessary government incentives on HEV sales for the expansion of HEV market in Korea. This work could contribute to the design of government policy to promote environmentally friendly vehicles. Additionally, this work can serve to analyze the effect of such incentive policies on environmental conservation and reduction of social expenses.
Administrators’ Awareness, Procurement and Management of Virtual Laboratories for Teaching Science Subjects in Secondary Schools: A Case Study
Authors: Ukpabio Godfrey E. , Ekanem Ekpenyong E. , Mbon Usen F. , Arop Festus O.
Published: June 2020

Previous studies have documented numerous benefits of using Virtual Labs (VLs) in promoting effective teaching of science subjects. The low level of teachers’ awareness, accessibility, and utilization of VLs in schools is also known. To the researchers’ knowledge, what is yet to be known is the extent of administrators’ awareness, procurement, and management of VLs in schools which have implications on teachers’ accessibility and utilization of VLs. This study adopted a descriptive survey design. A questionnaire (AAPMVLQ), with Cronbach alpha (α = .83), was administered to a sample of 662 secondary school principals and vice-principals drawn from 271 public schools in Cross River State Nigeria. Findings revealed that the level of administrators’ awareness, procurement, and management of VLs in secondary schools is very low. The low level of awareness was attributed to the poor supply of modern facilities to schools in the area of study. While the low levels of procurement and management were attributed to the low level of awareness of administrators. The conclusion and implications of these findings are that the teaching of science subjects at the secondary school level is witnessing a major setback and will continue if immediate actions are not taken to redress this issue. The poor academic performance of students in science subjects could also be liberated in the future if lessons are made more experiential by providing modern teaching aids such as VLs.
BİLİRKİŞİLİK KURUMU VE BİLİRKİŞİ RAPORUNUN DELİL DEĞERİNE İLİŞKİN BAZI SORUNLAR
Authors: ERDOĞAN Ersin , ÜÇÜNCÜ Sümeyye Hilal
Published: June 2020

Hukuk Muhakemeleri Kanunu'nun 266 ilâ 287'nci maddeleri arasında, medenî yargı açısından bilirkişi incelemesi düzenlenmiştir. Hukuk Muhakemeleri Kanunu'nun 282'inci maddesinde, hâkimin bilirkişinin oy ve görüşünü serbestçe değerlendireceği belirtilmiştir. Bu çalışmada, hâkimin bilirkişinin oy ve görüşünü serbestçe değerlendirmesinden ne anlaşılması gerektiği, hem karşılaştırmalı hukuk hem de Türk hukuku doktrin ve uygulaması açısından tartışılmaktadır. Bu çerçevede, hâkimin bilirkişiye re'sen müracaat edip edemeyeceği ve şahsî bilgisinin kullanıp kullanamayacağı sorunları değerlendirilmiştir. Ayrıca, Türk Medenî Kanunu'nun 4'üncü maddesi anlamında hâkimin takdir yetkisi ile delillerin değerlendirilmesi açısından hâkimin takdir yetkisi arasındaki farka işaret edilmiştir.
ІННОВАЦІЇ У СФЕРІ БАНКІВСЬКОГО БІЗНЕСУ
Authors: Клюско Л. А.
Published: June 2020

У статті досліджено сутність банківських інновацій в Україні, виокремлено їх види та визначено особливу роль в модернізації діяльності, забезпеченні конкурентоспроможності і фінансової стійкості банків, а також в розвитку економіки в цілому. Приділено увагу інноваційним наглядовим інструментам НБУ, таким як: вимога щодо формування та визначення кожним банком бізнес-моделі його діяльності; запровадження комплексної наглядової оцінки SREP (Supervisory review and evaluation process), за якою визначається життєздатність бізнес-моделі і стійкість стратегії розвитку банку.
The Role of Integrated Healthcare Center in Giving Service to Community of Cot Teugoh, Pidie Sub-District, Pidie Regency
Authors: Salahuddin  , Ismail
Published: June 2020

Integrated Healthcare Center is carried out by the community at the village level, once a month. The purpose of implementing Posyandu is to find out the Role of Integrated Service Post Officers (Posyandu) in optimizing services to the community in Teugoh Cot Village, Pidie District, Pidie Regency and to find out the barriers of Integrated Healthcare Center in optimizing services to the community in Teugoh Cot Village, Pidie District Pidie Regency by using a qualitative descriptive approach. The informants of this study were 1 midwife, 1 nurse, 1 Posyandu officer, 2 community members. The results of the study found that, 1) The role of Poyandu officers in Teugoh Cot Village was not optimal. Integrated Healthcare Center officers come to Geuceu Iniem Village only once a month, namely the fourth month. Integrated Healthcare Center officers arrive at 10:00 until 11:30 noon. In carrying out their duties, Posyandu officers work less optimally and in serving the community less effectively, 2) Obstacles faced by Integrated Healthcare Center officers, lack of funds in implementing Integrated Healthcare Center programs, both medical equipment and others. Given that Integrated Healthcare Center is a program from the Public health center, very little funding was obtained to process the Posyandu program for the better.
The Needs Analysis of Thematic Learning Model Based on Aneuk Jamee Culture Integrated with HOTS
Authors: Mardhatillah  , Khairil Ansari  , Abdurahman Adisaputera
Published: June 2020

The aim of this research is to analyze the needs of the development of the culture-based thematic learning model of the integrated Aneuk Jamee HOTS tribe. The study was conducted by survey method in 9 (nine) Elementary Schools in South Aceh Regency. The research subjects were 18 classroom teachers who taught thematic learning. The object studied was the principal's response to the development of a thematic learning model based on the Aneuk Jamee tribe integrated with HOTS, the tendency of teachers to apply thematic models in school learning, student reasoning, and student character. Data collected by interview, questionnaire, observation, and test. Data were analyzed descriptively. The results of the analysis show that (1) principals have not yet fostered the development of thematic models, so they support development efforts, (2) teachers have not yet developed and used thematic models, so they support and express readiness to be involved in development, (3) learning models used by teachers so far there are no indications that lead to thematic models based on aneuk jamee integrated HOTS
Harbour seals responded differently to pulses of out-migrating coho and Chinook smolts
Authors: Allegue H , Thomas AC , Liu Y , Trites AW
Published: June 2020

There is increasing evidence that predation by harbour seals on out-migrating salmon smolts may be responsible for the low return of adult coho and Chinook salmon in the Salish Sea. However, little attention has been given to understanding where and when this predation occurs and the extent to which it might be conducted by few or many seals in the population. We equipped 17 harbour seals with data loggers to track seal movements and used accelerometry to infer prey encounter events (PEEs) following the release of ~384000 coho (May 4, 2015) and ~3 million Chinook (May 14, 2015) smolts into the Big Qualicum River. We found a small proportion (5.7%) of all PEEs occurred in the estuary where salmon smolts entered the ocean—and that only one-quarter of the seals actively fed there. PEE counts increased in the estuary after both species of smolts were released. However, the response of the seals was less synchronous and occurred over a greater range of depths following the release of the smaller-bodied and more abundant Chinook smolts. Harbour seals feeding in the estuary appeared to target coho smolts at the beginning of May but appeared to pursue predators of Chinook smolts in mid-May. PEE counts in the estuary increased as tide height rose and were higher at dusk and night—especially during full moonlight. Such fine-scale behavioural information about harbour seals in relation to pulses of out-migrating smolts can be used to design mitigation strategies to reduce predation pressure by seals on salmon populations.
Penerapan Sistem Informasi Administrasi Di Pondok Pesantren Anak Dan Madrasah Ibtidaiyah Raudlatul Falah
Authors: Sudibyo Usman , Fanani Ahmad Zainul , Nurcipto Dedi
Published: June 2020

Program IbM (Pengabdian masyarakat) yang akan dilakukan di Pondok Pesantren Anak Tahfidzul Qur’an (PPATQ) dan Madrasah Ibtidaiyah (MI) Raudlatul Falah Desa Bermi Kecamatan Gembong Kabupaten Pati adalah dengan penerapan sistem informasi manajemen administrasi yang berbasis teknologi informasi komputer untuk menunjang layanan kepada orang tua/wali santri agar lebih baik dan akuntabel. Perkembagan lembaga pendidikan PPATQ dan MI Raudlatul Falah yang semakin pesat dengan jumlah santri sekarang mencapai 350 anak menjadi potensi sekaligus menjadi tantangan untuk dapat memberikan layanan yang lebih baik kepada masyarakat secara umum dan orang tua/wali santri secara lebih khusus. Proses administrasi pencatatan yang dilakukan dengan cara manual atau hanya memberikan kuitansi kepada orang tua yang kemudian ada staf lain yang melakukan rekapitulasi membuat sering terjadi miskomunikasi dan kesalahan dalam proses pencatatan sehingga muncul komplain yang tidak baik. Perkembangan teknologi informasi komputer yang cukup pesat saat ini diharapkan dapat menjadi solusi untuk menyelesaikan permasalahan yang dihadapi oleh lembaga ini supaya lebih dipercya oleh masyarakat. Penerapan teknologi Sistem Informasi Manajemen Administrasi dengan koneksi jaringan lokal area diharapkan mampu mengintegrasikan administrasi di pesantren dan madrasah sehingga lebih mudah, cepat dan raoi dalam pengaturan serta pelaporannya. Sistem database yang dibangun dengan baik akan menjamin pencatatan yang akurat karena transaksi data terpusat dalam satu database. Implementasi aplikasi ini diharapkan semakin mempercepat dan memudahkan orang tua, pengurus maupun pengelola dalam bertransaksi.
PENGEMBANGAN PUBLIC SPEAKING BAGI PENGURUS OSIS DI SMPN 30 SEMARANG
Authors: Purnamasari Devi , Pratiwi Mutia , Rosalia Naiza
Published: June 2020

Pengabdian Masyarakat tentang Pengembangan Kemampuan Pengurus OSIS dalam bidang Public Speaking di SMPN 30 Semarang bertujuan untuk meningkatkan keberanian siswa dalam menyampaikan gagasan dan soft skill berkaitan dengan penempatan diri dalam situasi tertentu. Pada pengabdian ini dipilih pengurus OSIS Sekolah dan beberapa perwakilan kelas karena berdasarkan observasi di lapangan, beberapa siswa seringkali merasa kurang percaya diri dalam menyampaikan gagasan mereka, masih merasa gugup ketika harus maju di hadapan orang baru saat harus menyelenggarakan event  dan belum memahami mengenai teknik-teknik dasar dalam public speaking. Sedangkan kemampuan public speaking merupakan salah satu keterampilan yang harus dimiliki pada siswa terutama ketika mereka menjabat sebagai pengurus OSIS di sekolah. Kemampuan public speaking selain melatih seni berbicara di depan umum, juga dapat meningkatkan kemampuan siswa untuk berani tampil didepan umum sehingga meningkatkan daya saing mereka diantara teman-teman sebayanya. Keterampilan public speaking diperhitungkan ketika siswa berada dalam suatu organisasi, mereka dapat menyampaikan gagasan/ide di depan umum dengan baik.
IbM PENERAPAN MICROSOFT OFFICE EXCEL UNTUK MENUNJANG PROFESIONALISME GURU DALAM PENGELOLAAN NILAI SISWA DI SD SYAHIDIN SEMARANG
Authors: Ningrum Novita Kurnia , Parti astuti Yani
Published: June 2020

Evaluasi merupakan salah satu bagian terpenting dalam kegiatan belajar mengajar di sekolah khususnya sekolah dasar. Hasil evaluasi dijadikan sebagai tolok ukur tercapainya tujuan dari pembelajaran yang sudah berlangsung. Salah satu bentuk evaluasi adalah pemberian scorring  atau penilaian pada siswa selama pembelajaran berlangsung. Penilaian yang sudah ada perlu diolah sesuai dengan kebutuhan data nilai dari guru yang bersangkutan. Selama ini guru di SD Syhidin mengolah data nilai siswa dengan menghitung manual. Beberapa kendala yang dialami oleh guru adalah belum mampu mengolah nilai secara komputerisasi  sdangkan mengolah data nilai secara manual membutuhkan waktu lama dan hasilnya belum tentu akurat. Hal tersebut tidak sesuai  dengan kondisi saat ini, karena guru diharapkan dapat memberikan informasi nilai dengan cepat. Oleh karena itu guru membutuhkan ketrampilan dalam hal pengolahan data secara otomatis dengan memanfaatkan teknologi yang ada. Microsoft Office Excel dapat digunakan sebagai media untuk mengelola data nilai siswa, baik menghitung secara aritmatika, memilah data dan diagram. Memalaui kegiatan IPTEK bagi masyarakat ini, diberikan materi berupa teori text dan praktikum. Para guru SD Syahidin mempraktikkan langsung menggunakan Microsoft Office Excel. Adapun materi praktikum meliputi menghitung aritmatika, memilah data, menyajikan nilai dalam tabel dan diagram. Dengan adanya kegiatan IPTEK bagi masyarakat ini, diharapkan guru di SD Syahidin mampu mengolah data nilai secara terkomputerisasi dan menghasilkan informasi nilai yang lebih akurat
Pembelajaran Matematika dan Bahasa Inggris dengan Metode Total Physical Response (TPR) di TK Al Firdaus Kandri Gunungpati Semarang
Authors: Astuti Yani Parti , Subhiyakto Egia Rosi , Umaroh Liya
Published: June 2020

Dalam perkembangan ilmu pengetahuan di Indonesia, matematika dan bahasa inggris merupakan ilmu dasar yang harus dipelajari oleh setiap anak pelajar di Indonesia. Sehingga materi matematika dan bahasa inggris sudah dikenalkan sejak pendidikan anak  usia dini. Namun di pendidikan anak usia dini hanya diajarkan berhitung untuk matematika dan pengenalan benda pada bidang bahasa inggris. Hal ini terjadi pada TK Al Firdaus Kandri Gunungpati Semarang. Di TK Al Firdaus ini anak – anak sudah diajarkan mengeja huruf, berhitung dan juga bahasa inggris..Dalam pengabdian ini dikenalkan metode pembelajaran yang dinamakan Total Phycical Response (TPR). Metode ini merupakan metode pembelajaran di mana anak diajarkan materi dengan menggunakan gerakan. Hal ini paling cocok untuk materi bahasa inggris yang untuk mengenalkan benda dan juga melakukan suatu pekerjaan. Dalam materi matematika akan diselipkan juga materi berhitung dalam bahasa inggris dengan jari. Melalui pembelajaran ini, maka anak – anak di TK Al Firdaus semakin mencintai pelajaran berhitung dan bahasa inggris pada khususnya. Karena mengingat tempat TK Al Firdaus berada di desa wisata kandri. Sangat mendukung apabila generasi – generasinya pandai berbahasa inggris dan juga berhitung. Selain itu materi ini bisa untuk bekal memasuki jenjang berikutnya yaitu Sekolah Dasar (SD).
Implementasi E-Learning Menggunakan Edmodo bagi Guru-Guru SD Kecamatan Cawas, Klaten
Authors: Mulyono Ibnu Utomo Wahyu , Rachmawanto Eko Hari , Susanto Ajib , Sari Christy Atika , Moses De Rosal Ignatius , Prabowo Dwi Puji , Ihya‘ Ulumuddin Dimas Irawan
Published: June 2020

Perkembangan Information and Communication Technology (ICT) atau Teknologi Informasi dan Komunikasi (TIK) dalam beberapa dekade terakhir berjalan sangat cepat sejalan dengan perkembangan teknologi telekomunikasi, termasuk jaringan komputer. Berbagai kendala dialami guru dalam pembelajara di tingkat SD yang siswanya tergolong generasi Z yang sudah menikmati keajaiban internet, guru dituntut dapat membuat desain instruksional, penguasaan TIK sebagai sumber pembelajaran yang up to date dan juga mampu menciptakan relasi dengan orang tua. Untuk mengatasi hal tersebut diperlukan pembelajaran berbasis e-learning yang mampu merelasikan antara guru-siswa-orangtua dalam meningkatkan proses belajar dengan menggunakan Edmodo. Tujuan e-learning ini agar proses belajar mengajar dapat berjalan lebih efektif dan melibatkan semua pihak terutama guru-siswa-orangtua dan pihak sekolah. Hasil dari pelatihan e-learning dengan Edmodo ini yaitu guru mampu menyajikan materi yang sudah dibuat baik slide, video dan text yang nantinya siswa dan orangtua dapat terlibat, pemberian tugas juga dapat dilakukan secara online sehingga efektifitas proses belajar mengajar sebagai suplemen belajar di kelas dapat dilakukan dengan baik.
PENDAMPINGAN PENINGKATAN SANTRIPRENEUR PADA SISWA-SISWI PONDOK PESANTREN USWATUN HASANAH SEBAGAI BEKAL MENJADI WIRAUSAHA
Authors: Mahmud Mahmud , Sartika Mila , Adinugraha Hendri Hermawan
Published: June 2020

Indonesia membutuhkan sedikitnya 4 (empat) juta wirausahawan baru untuk turut mendorong penguatan struktur ekonomi. Saat ini jumlah wirausahawan masih sekitar 3,1% dari total populasi penduduk atau sekitar 8,06 juta orang. Data menurut Menteri Perindustrian bahwa meskipun rasio tersebut sudah melampaui standar internasional, yaitu sebesar 2%, akan tetapi Indonesia masih mengejar capaian negara tetangga. Kementerian Koperasi dan UKM melansir data olahan BPS dan menyimpulkan adanya pertambahan jumlah pengusaha yang dari sebelumnya 1,6% menjadi 3,1% dari populasi. Angka itu menggembirakan karena telah menembus batas psikologis 2%. Jumlah wirausaha di suatu negara kerap dianggap sebagai indikator kemajuan. Patokannya minimal 2% dari jumlah penduduk harus berprofesi sebagai wirausaha. Dengan jumlah penduduk 250 juta jiwa, negeri ini paling kurang harus memiliki 5 juta jiwa wirausaha.Tujuan dari pelaksanaan pengabdian ini adalah menambah pengetahuan dan pemahaman bagi siswa-siswi pondok pesantren Uswatun Hasanah Semarang tentang kewirausahaan, membantu siswa-siswi pondok pesantren Uswatun Hasanah agar mampu membuka mindset untuk menjadi wirausaha dan dapat membantu menggali ide untuk berwirausaha.Metode pelaksanaan kegiatan ini menggunakan pendekatan edukasi, sosialisasi dan pelatihan serta pendampingan bagi siswa-siswi pondok pesantren Uswatun Hasanah Semarang, dengan metode pelatihan kewirausahaan. Sedangkan luaran yang dihasilkan dari kegiatan pengabdian ini adalah siswa-siswi pondok pesantren Uswatun Hasanah memiliki pengetahuan tentang kewirausahaan dan dikemudian hari mampu berwirausaha.
Deteksi Perkembangan Anak Usia 3 Bulan – 72 Bulan Menggunakan Kuesioner Pra Skrining Perkembangan (KPSP)
Authors: Entoh Christina , Noya Fransisca , Ramadhan Kadar
Published: June 2020

More than a third of children in the world experience growth and development disorders both physically and mentally, and an estimated 5 to 10% of the child population has developmental delays. Child development problems such as motor delays, language, behavior, autism, hyperactivity, have increased in recent years, the occurrence in the United States ranges from 12-16.6%, Thailand 24%, Argentina 22.5%, and in Indonesia between 13 % -18%. Approximately 16% of children under five years old (toddlers). Indonesia experiences neurological and brain development disorders ranging from mild to severe. The purpose of this study is to increase the motivation of toddlers to carry out routine child development checks, increase the participation of toddlers to carry out child development checks using KPSP, early detection of growth, and developmental disorders. The method used in this community service is varied lectures. The speakers did a demonstration to mothers who have children of 3  - 72 months. Each mother gave information about their child's age and early detection of growth and development using KPSP according to the age child age. Results: Out of 140 children aged 3 - 72 months who were detected developmentally using the Pre Development Screening Questionnaire (KPSP), there were 134 children (95.7%) with normal results and 6 people (4.3%) with doubtful results and none (0%) who experienced deviance. Conclusion:  The 6 children with doubtful screening results, after 2 weeks of screening, obtained 100% normal developmental results. Suggestion: Early detection can find growth disorders and child development, therefore, an intervention can be done as early as possible.
Pelaksanaan Permainan Ular Tangga dalam Kelas Ibu Hamil
Authors: Longgupa Lisda Widianti , Nurfatimah Nurfatimah , Siregar Nilda Yulita
Published: June 2020

The efforts to reduce maternal and infant mortality can be done by increasing the coverage and quality of maternal and child health services. One effort is made to bring health services closer to the community through the pregnant mothers class program. Pregnant woman class is a study group of pregnant women with gestational age between 4 weeks to 36 weeks with a maximum number of 10 participants. In this class, pregnant women will learn together, discuss and exchange experiences on overal maternal and child health, facilitated by midwives or health workers by using the class package for pregnant women, namely flip chart, guidelines for implementing classes of pregnant women,  class facilitator’s handbook pregnant women, exercise books for pregnant women  and books on maternal and child health (MCH). Based on the results of community service activities with participants of 40 pregnant women there was an increase in correct answers to all participants after participating in class activities for snakes ladderss of pregnant women. From the pre-test result it turns out that most of the results obtained were less than 60. This shows that the knowledge ability of pregnant women is still lacking. However, after holding the snakes ladder pregnant class, there was an increase in the knowledge of pregnant women with an increase in the post-test score point in the range between 21-30 (47.5%).
Genetic Variability and Population Structure in the Sardinian Anglo-Arab Horse
Authors: Giontella Andrea , Sarti Francesca Maria , Cardinali Irene , Giovannini Samira , Cherchi Raffaele , Lancioni Hovirag , Silvestrelli Maurizio , Pieramati Camillo
Published: June 2020

The Sardinian Anglo Arab (SAA) is a famous horse breed in Italy, with a significant historical background in the island of Sardinia. The aim of the study is to perform an evaluation of genetic variability in SAA using pedigree and mitochondrial data. In the current population, pedigree completeness was observed to be close to 100%, while the inbreeding coefficient and the average relatedness were lower than 3%. The ratio of effective founders/numbers of ancestors was 3.68 for the whole pedigree. The effective population size (Ne) computed by an individual increase in inbreeding (Ne_1) was 456.86, the Ne on equivalent generations (Ne_2) was 184.75, and this value slightly increased to 209.31 when computed by log-regression on equivalent generations (Ne_3). These results suggest the presence of crossbreeding and bottleneck phenomena, and they were compared with other Italian horses (reported in bibliography) to present the SAA among the Italian horse breeds scenario. Furthermore, the noteworthy mitochondrial variability reflects the use of a considerable number of founder mares; the contribution of L lineage was very important, probably because of the re-colonization from the Iberian Peninsula after the Last Glacial Maximum.
Understanding Digital Radio Frequency Memory Performance in Countermeasure Design
Authors: Davidson Kyle , Bray Joey
Published: June 2020

This paper describes the design, implementation, and testing of a novel multi-function software defined Radio Frequency (RF) system designed for small airborne drone applications. The system was created using an inexpensive Field Programmable Gate Array (FPGA) to combine a coherent linear frequency modulated radar transmitter and receiver, with a Digital Radio Frequency Memory (DRFM) jammer for use with a common RF aperture in simultaneous operation. The system was implemented on a Xilinx Kintex-7 FPGA with a wideband analogue-to-digital/ digital-to-analogue (ADC/DAC) converter mezzanine board and tested using hardware-in-the-loop mode to validate its performance. This is the first known account of an integrated multifunction electronic attack and radar system on a single chip, capable of performing a simultaneous, not time shared, operation.
A Qualitative Study of the Ionospheric Weak Response to Super Geomagnetic Storms
Authors: Li Haimeng , Chen Zhou , Xie Lianqi , Li Fan
Published: June 2020

The ionospheric response to a geomagnetic storm is a geophysical process. Although strong geomagnetic storms input more energy into the Earth’s upper atmosphere, the ionospheric response often does not reflect the same level of variation as the geomagnetic storm, and the response may be weak during a very strong storm. However, the estimated ionospheric response to geomagnetic activity also varies with extraction method. Here, two different methods—the spectral whitening method (SWM) and the monthly median method (MMM)—are used to verify whether the apparent weak ionospheric response is an artifact of the processing method. The weak ionospheric response is found with both methods, which suggests it is a real ionospheric phenomenon. The statistical characteristics of the regional and global ionospheric weak response to a super geomagnetic storm (SGS) and to an SGS with a preceding storm event (SGS-PRE) are investigated and compared. The results show that the regional ionospheric weak response to an SGS is more prevalent at middle latitudes than those at low and high latitudes. The global ionospheric weak response occurs more frequently under high solar activity and has a strong correlation with SGS-PRE, which suggests that the effect of a storm on the ionosphere can be influenced by its preconditioning, especially when there is an earlier storm and the time interval between the two storms is short. In fact, an ionospheric long-lasting disturbance may be an important reason for the ionospheric weak response caused by the SGS-PRE.
High-Temperature Optical Spectra of Diatomic Molecules: Influence of the Avoided Level Crossing
Authors: Beuc Robert , Pichler Goran
Published: June 2020

In this study, we analyzed the light absorption by diatomic molecules or colliding atoms in a spectral region dominated by an avoided crossing of adiabatic state levels or crossing of the corresponding diabatic state levels. Our attention was focused on the low-resolution spectrum at a higher gas temperature under local thermodynamic equilibrium conditions. The absorption measurements of mixed vapors of potassium (≈80%) and cesium (≈20%) were made in the temperature range of 542–715 K and the infrared spectral range 900–1250 nm. In this area, the main spectral contributions were the broad A 1 Σ ( u ) + ( 0 ( u ) + ) − X 1 Σ ( g ) + ( 0 ( g ) + ) bands of K2, Cs2, and KCs molecules. There was a crossing of A 1 Σ ( u ) + ( 0 ( u ) + ) and b 3 Π ( u ) ( 0 ( u ) + ) state potential curves and the coupling of this state was due to the matrix element ⟨ A 1 Σ ( u ) + ( 0 ( u ) + ) | H s o | b 3 Π ( u ) ( 0 ( u ) + ) ⟩ of the spin–orbit interaction. Using data for relevant electronic potential curves and transition dipole moments existing in the literature, the spectra of the A 1 Σ ( u ) + ( 0 ( u ) + ) − X 1 Σ ( g ) + ( 0 ( g ) + ) molecular bands of K2, Cs2, and KCs molecules were calculated. Full quantum mechanical and semi-quantum coupled channel calculations were done and compared with their non-coherent adiabatic or diabatic approximations. Through the comparison of our theoretical and experimental spectra, we identified all observed spectral features and determined the atoms’ number density and gas temperature.
Development of a Pulsatile Flow-Generating Circulatory Assist Device (K-Beat) for Use with Veno-Arterial Extracorporeal Membrane Oxygenation in a Pig Model Study
Authors: Fujii Yutaka , Akamatsu Nobuo , Yamasaki Yasunori , Miki Kota , Banno Masayuki , Minami Kenta , Inamori Shuji
Published: June 2020

Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) preserves the life of heart failure patients by providing an adequate oxygen supply and blood flow to vital organs. For patients with severe cardiogenic shock secondary to acute myocardial infarction or acute myocarditis, V-A ECMO is commonly used as the first choice among cardiac circulatory support devices. While V-A ECMO generates circulatory flow using a centrifugal pump, the provision of pulsatile flow is difficult. We previously reported our development of a new circulatory flow assist device (K-beat) for cardiac management with pulsatile flow. To obtain more efficient pulsatile assist flow (diastolic augmentation), an electrocardiogram (ECG)-analyzing device that can detect R waves and T waves increases the assist flow selectively in the diastole phase by controlling (opening and closing) the magnetic valve of the tamper. Here, we describe the first use of the K-beat on a large animal in combination with a clinical device. In addition, the diastolic augmentation effect of the K-beat as a circulatory flow assist device was examined in a pig V-A ECMO model. The K-beat was stopped every 60 min for a period of a few minutes, and blood pressure waveforms in the pulsatile and non-pulsatile phases were checked. This experiment showed that stable V-A ECMO could be achieved and that hemodynamics were managed in all animals. The pulsatile flow was provided in synchrony with the ECG in all cases. A diastolic augmentation waveform of femoral arterial pressure was confirmed in the pulsatile phase. K-beat could be useful in patients with severe heart failure.
Postnatal Guinea Pig Brain Development, as Revealed by Magnetic Resonance and Diffusion Kurtosis Imaging
Authors: Mullins Roger J. , Xu Su , Zhuo Jiachen , Roys Steve , Pereira Edna F.R. , Albuquerque Edson X. , Gullapalli Rao P.
Published: June 2020

This study used in vivo magnetic resonance imaging (MRI) to identify age dependent brain structural characteristics in Dunkin Hartley guinea pigs. Anatomical T2-weighted images, diffusion kurtosis (DKI) imaging, and T2 relaxometry measures were acquired from a cohort of male guinea pigs from postnatal day (PND) 18–25 (juvenile) to PND 46–51 (adolescent) and PND 118–123 (young adult). Whole-brain diffusion measures revealed the distinct effects of maturation on the microstructural complexity of the male guinea pig brain. Specifically, fractional anisotropy (FA), as well as mean, axial, and radial kurtosis in the corpus callosum, amygdala, dorsal-ventral striatum, and thalamus significantly increased from PND 18–25 to PND 118–123. Age-related alterations in DKI measures within these brain regions paralleled the overall alterations observed in the whole brain. Age-related changes in FA and kurtosis in the gray matter-dominant parietal cerebral cortex and dorsal hippocampus were less pronounced than in the other brain regions. The regional data analysis revealed that between-age changes of diffusion kurtosis metrics were more pronounced than those observed in diffusion tensor metrics. The age-related anatomical differences reported here may be important determinants of the age-dependent neurobehavior of guinea pigs in different tasks.
Silence, Solitude, and Serotonin: Neural Mechanisms Linking Hearing Loss and Social Isolation
Authors: Keesom Sarah M. , Hurley Laura M.
Published: June 2020

For social animals that communicate acoustically, hearing loss and social isolation are factors that independently influence social behavior. In human subjects, hearing loss may also contribute to objective and subjective measures of social isolation. Although the behavioral relationship between hearing loss and social isolation is evident, there is little understanding of their interdependence at the level of neural systems. Separate lines of research have shown that social isolation and hearing loss independently target the serotonergic system in the rodent brain. These two factors affect both presynaptic and postsynaptic measures of serotonergic anatomy and function, highlighting the sensitivity of serotonergic pathways to both types of insult. The effects of deficits in both acoustic and social inputs are seen not only within the auditory system, but also in other brain regions, suggesting relatively extensive effects of these deficits on serotonergic regulatory systems. Serotonin plays a much-studied role in depression and anxiety, and may also influence several aspects of auditory cognition, including auditory attention and understanding speech in challenging listening conditions. These commonalities suggest that serotonergic pathways are worthy of further exploration as potential intervening mechanisms between the related conditions of hearing loss and social isolation, and the affective and cognitive dysfunctions that follow.
Relationship between Auditory Evoked Potentials and Circadian Preference in Patients with Major Depressive Episodes
Authors: Park Young-Min
Published: June 2020

Mood disorders often accompany circadian rhythm abnormalities. The serotonergic system (STS) is related to mood and circadian rhythm. This study aimed to test whether serotonergic neurotransmission, using the loudness dependence of auditory evoked potential (LDAEP), is associated with circadian preference in patients with major depressive disorder (MDD). Depression severity was assessed in 18–65-year-old outpatients (n = 48) using the Beck Depression Inventory scores and Hamilton Depression Rating Scale at baseline. Additionally, various scales, including the Korean version of the Composite Scale of Morningness (K-CSM), Korean version of the Mood Disorder Questionnaire (K-MDQ), and Korean version of the Childhood Trauma Questionnaire (K-CTQ), were used. LDAEP was also measured at baseline. The subjects were divided into three groups according to the circadian preference using total K-CSM scores (morningness (n = 10) vs intermediate (n = 19) vs. eveningness (n = 19)) and two groups according to median based on each K-CSM score, respectively (higher K-CSM (n = 25) vs. lower K-CSM (n = 23)). The bipolarity, suicidality, and age at onset differed among the three groups. Impulsivity, depression severity, suicidality, hopelessness, bipolarity, frequency of emotional abuse, and age at onset differed between the two group divisions. Thus, the STS might serve as the mediator between the circadian system and mood.
National Policies to Prevent and Manage Cervical Cancer in East African Countries: A Policy Mapping Analysis
Authors: Njuguna Diana Wangeshi , Mahrouseh Nour , Onisoyonivosekume Dede , Varga Orsolya
Published: June 2020

Policy mapping is used to provide evidence on effective interventions and highlight the necessary refinements of health policies. The goal of this work is to carry out legal mapping to identify and assess health policies for the prevention and management of cervical cancer in East African countries. Cervical cancer, as a largely preventable disease, is the cause of most cancer deaths among women in East African countries. Legal documents were searched uniformly from government websites, national cancer institute sites, and international and national legal databases, then the data were analyzed using the Nvivo12 software package. The sample of 24 documents includes policies, plans, guidelines, acts, and strategies from 12 East African countries. The emerging themes were screening, prevention, diagnosis, treatment, challenges, and mitigation efforts. A few binding policies, a significant discrepancy to international standards in at least four countries, patchy screening registries, and a lack of prophylactic vaccination against human papillomavirus incorporation into national immunization schedules are the main findings. This paper underlies the role of law in health and the need for transparent legal and regulatory tools to achieve a further reduction in cervical cancer mortality in East African countries.
Beneficial Molecular Adaptations in BRCA-Mutation Carriers by Combined HIT/HIRT Intervention: Results from a Pilot Study
Authors: Bizjak Daniel A. , Schulz Sebastian V. W. , Schumann Uwe , Otto Stephanie , Kirsten Johannes , Ebner Florian , Leinert Elena , Huober Jens , Janni Wolfgang , Steinacker Jürgen Michael
Published: June 2020

Based on growing evidence that breast cancer (BRCA) also plays a pivotal role in the regulation of skeletal muscle metabolism and the response to anti-oxidative stress, we examined the influence of regular exercise in human BRCA mutation carriers on their BRCA1 gene/protein expression and inflammatory/oxidative response. Sixteen BRCA-mutation carriers were assigned to an intervention (IG) or control group (CG). IG received a combination of high-intensity interval endurance (HIT) and strength training (HIRT) for six weeks, whereas CG received a low-intensity activity program. Before (T0) and at the end of the intervention (T1), muscle biopsy, physiological performance, blood withdrawal and anthropometry were obtained. Parameters included: Muscle BRCA1 gene/protein expression, inflammatory/oxidative stress, anti-oxidative capacity, peak oxygen capacity (VO2peak) and 1-repetition maximum (1-RM) at six different training machines. VO2peak and 1-RM of IG were increased at T1 compared to T0, whereas CG performance, physiological and molecular parameters remained unchanged. IG showed increased BRCA1 protein concentration as well as anti-oxidative capacity, whereas gene expression was unaltered. IG inflammatory and oxidative damage did not differ between time points. Combined HIT/HIRT increases aerobic and strength performance of BRCA-mutation carriers with up regulated BRCA1 protein expression and improved anti-oxidative status without showing an increased inflammatory response.