bluuebunny/crossref_metadata_2025 huggingface dataset:
Delivery of mobile dental services to dependent elderly people: results from a pilot study in rural Switzerland
Authors: Borg-Bartolo Roberta , Von Wyttenbach Thomas , Keller Michael J. , Schirrmann Eric , Al Hajj Aya , Essig Stefan
Published: March 2024

The objective of this pilot study was to provide data on the oral health status and oral health behaviour of care-dependent elderly people in the canton of Uri. The study aimed at assessing whether age and duration of living in a nursing home is associated with dental attendance, whether there is a relationship between age and the DMF-T index, and how high the risk was for participants to develop oral health problems.The study offered mobile dental services to people residing in nursing homes (NHG) and to community dwellers (CDG). Data was collected on demographics, medical history, presence of pain, ability to eat and oral health behaviour by means of a questionnaire. A clinical examination was per- formed and data on the oral status was collected. Statistical methods were: median tests, linear regressions and descriptive statistics.Uptake of the programme was low. 56 participants were examined. 47 participants (24 females, 23 males, average age 86.3 ± 7.36 years) resided in nursing home, 9 participants (7 females,2 males, average age 76 ± 12.8 years) were com- munity dwellers. No significant differences were found between frequency of dental attendance and age (p = 0.35) or duration of stay in a nursing home (p = 0.55). The number of decayed teeth(p = 0.005), missing teeth (p = 0.01), and the DMF-T index (average in NHG = 26.5, CDG = 20.2,p < 0.001) increased, the number of filled teeth (p = 0.02) decreased as age increased. Upon calculation of the Teamwerk index, which takes into account oral health behaviour, dental caries, and periodontal status, the majority of participants had a medium risk of developing oral health problems.Our pilot study in rural Switzerland provides first results of the oral health status in dependent elderly people. As people age, oral health deteriorates. More attention should be given to oral hygiene maintenance and more regular dental visits, to ensure a better oral health status in dependent elderly people.
Pentoxifyllin und Tocopherol
Authors: Marjanowski Simon David , Maldonado Alejandra , Schaller Benoît , Burkhard John-Patrik Matthias
Published: March 2024

Die Osteoradionekrose (ORN) ist eine schwer- wiegende Komplikation nach Radiotherapie bei Kopf-Hals-Tumoren und stellt aufgrund der schwierigen Therapie eine Herausforderung an den Behandler und den Patienten dar. Verschiedene nicht invasive Ansätze wurden zur Behandlung von geringgradigen ORN-Fällen bereits publiziert, jedoch ohne Etablierung eines Therapiestandards. Aufgrund des 2004 publizierten Ansatzes der ORN-Pathogenese – des sogenannten Radiatio-induzierten fibroatrophischen Prozesses (RIF) – wurde ein neues Behandlungskonzept mit Pentoxifyllin und Tocopherol (PENTO) veröffentlicht. Vielversprechend scheinen die Ergebnisse der PENTO-Therapie als konservativer Behandlungsansatz bei leichtgradiger ORN oder als Alternative, wenn kein chirurgischer Eingriff möglich oder erwünscht ist. Die vorliegende Arbeit fasst den aktuellen Stand der Literatur zusammen und zeigt die Effektivität der PENTO- Therapie anhand eines Fallberichts.
Restoration of teeth affected by molar-incisor hypomineralisation: a systematic review
Authors: Weber Kathrin R. , Wierichs Richard J. , Meyer-Lückel Hendrik , Flury Simon
Published: March 2024

The objective was to systematically analyse clinical studies on restorative procedures for teeth affected by molar-incisor hypomineralisation (MIH). The databases PubMed, Embase, and Cochrane Library were searched. Only retrospective and prospective clinical studies dealing with sealing or restoration of MIH-affected teeth were included. The language was restricted to English or German. Thirteen of 36 potentially eligible studies were included focusing on the following subjects: extension of enamel preparation, adhesive procedures prior to restoration, application of fissure sealants as well as restoration with conventional glass ionomer cements (GIC), resin modified glass ionomer cements (RMGIC), resin composites, and indirect restorations. Seven clinical studies were controlled trials. However, only two included MIH-unaffected teeth as control. No meta-analysis was performed due to the heterogeneity of study designs (e.g. severity of MIH or the restorative materials investigated). Based on the present analysis, the annual failure rates were in average 21% for fissure sealants, 22% for GIC, 1-6% for RMGIC, 13-32% for resin composites, and 0-7% for indirect restorations. In summary, only few tendencies can be deduced from this review at a low level of evidence (number of studies): 1) preparation margins in sound enamel seem to be superior to preparations in hypomineralised enamel (1 study), 2) RMGIC seems to be superior to GIC (3 studies), 3) resin composites may be used for restoring all severities of MIH (7 studies) with self-etch and etch-and-rinse adhesive systems generally not performing differently (3 studies), and 4) in cases of severe MIH, indirect restorations showed a good clinical success (4 studies).
Ausgedehnte unilaterale Osteosklerose im Unterkiefer eines Kindes
Authors: Schiefersteiner Mona , Valdec Silvio , Häberle Johannes , Baumhoer Daniel , Stadlinger Bernd
Published: March 2024

Eine kieferorthopädische Abklärung zeigte bei einer achtjährigen Patientin als Zufallsbefund eine Osteosklerose mit verlagerten Zahnkeimen im linken Unterkiefer. Bei der Patientin sind keine Grunderkrankungen bekannt. Extraoral besteht ein normales Hautkolorit ohne Asymmetrie mit intakter Sensibilität und Motorik. Intraoral zeigt sich ein altersentsprechendes Wechselgebiss mit dezent aufgetriebenem Unterkiefer links.
Aussergewöhnliche Schleimretentionszyste im Kieferknochen imponiert radiologisch als radikuläre Zyste
Authors: Von Arx Thomas , Bräutigam Konstantin , Banz Yara , Bornstein Michael M.
Published: March 2024

Eine der häufigsten Pathologien im Kieferbereich ist eine bakteriell verursachte Entzündung an den Wurzelspitzen der Zähne mit nachfolgendem Knochenabbau, der sich im Röntgenbild als Radioluzenz (Aufhellung) präsentiert. In der Regel korrelieren die entsprechenden klinischen und radiologischen Befunde und ermöglichen eine klare Diagnostik. Gelegentlich kommt es jedoch zu einer unerwarteten und ganz anderen Diagnose, wie der vorliegende Fallbericht dokumentiert. Bei einer 55-jährigen Patientin wurde im Oberkiefer rechts eine radikuläre Zyste vermutet, die mittels Zystektomie sowie Wurzelspitzenresektionen der benachbarten und wurzelkanalgefüllten Zähne 15 und 16 therapiert werden sollte. Das intraoperative Bild entsprach jedoch überhaupt nicht dem einer radikulären Zyste, sondern eher einer Schleimretentionszyste, die in der Folge auch histopathologisch bestätigt werden konnte. Die Diagnose einer im Kieferknochen liegenden Schleimretentionszyste ist aussergewöhnlich und so noch nie in der Literatur beschrieben worden.
Plaque bei Brackets: Probleme und Lösungen
Authors: Schmidlin Patrick R. , Schmidlin Andrin D. , Gubler Andrea , Attin Thomas , Lussi Adrian
Published: March 2024

Kieferorthopädische Apparaturen mit Brackets erschweren die Mundhygiene, was bei unge­nügender mechanischer Plaquekontrolle über längere Zeit zu einem deutlich erhöhten Ka­ries­ und Gingivitisrisiko führt. Während klas­sische Mundhygieneindizes auf Glattflächen und Approximalräume abzielen, gibt es mitt­ lerweile Modifikationen im Rahmen kiefer­orthopädisch behandelter Zähne mit Brackets.
Metronidazol – Wirkungsspektrum, Anwendung und Nebenwirkungen
Authors: Wallner Jürgen , Rieder Marcus , Schwaiger Michael , Pau Mauro , Zrnc Tomislav , Zemann Wolfgang , Metzler Philipp
Published: March 2024

Dieser Beitrag gibt einen Überblick über die Anwendung, die therapeutischen Wirkungen und die Nebenwirkungen der antibiotischen Substanz Metronidazol. Metronidazol ist wirksam zur Unterstützung der Behandlung von Parodontitis, mikrobiell bedingtem Mundgeruch, perioralen Hautinfektionen und odontogenen Hart- oder Weichgewebeabszessen, die auf anaerobe bakterielle Infektionen zurückzuführen sind. Aufgrund seiner antiparasitären Wirkung ist Metronidazol auch bei der Behandlung von Protozoen wirksam. Bei Erwachsenen und Kindern ab 12 Jahren können 200 mg Metronidazol bis maximal 2000 mg Metronidazol pro Tag verabreicht werden. Bei Kindern unter 12 Jahren wird eine antibiotische Dosis von Metronidazol zwischen 20 und 30 mg pro Kilogramm Körpergewicht empfohlen.
THE SCIENCE OF MACHINE LEARNING PART-2
Authors: SHAH VARUN , CHOPRA TARUNA , ABDUFATTOKHOV SHOKHJAKHON , RAY Dr. SOUMI
Published: March 2024

The book titled “The Science of Machine Learning” serves as a comprehensive guide for both beginners and experienced practitioners in the field of machine learning. Covering a wide range of topics, the book provides a thorough introduction to the fundamentals of machine learning, as well as advanced techniques and emerging trends. Chapter 8 focuses on feature selection and model interpretability, discussing the importance of feature selection, techniques for feature selection, interpretable machine learning models, explainable AI (XAI) techniques, model debugging, error analysis, and visualization of model decisions. Chapters 9 and 10 delve into natural language processing (NLP) and computer vision, respectively, covering topics such as text preprocessing techniques, word embeddings, recurrent neural networks for NLP, transformer models, image preprocessing techniques, convolutional neural networks for image classification, object detection, image segmentation, and transfer learning. Chapter 11 introduces readers to reinforcement learning, discussing concepts such as Markov decision processes (MDP), Q-learning, policy gradient methods, deep reinforcement learning, and applications of reinforcement learning. In Chapter 12, readers learn about deploying machine learning models, including model deployment strategies, containerization and orchestration, model serving platforms, monitoring and scaling machine learning systems, ethical considerations in model deployment, and model maintenance and updates. Finally, Chapter 13 explores future trends and directions in machine learning, including the current state of machine learning research, emerging technologies and innovations, and ethical and societal implications of machine learning. The chapter concludes with final thoughts and reflections on the future of the field. Overall, “The Science of Machine Learning” provides a comprehensive overview of the field, equipping readers with the knowledge and skills necessary to embark on their journey in machine learning and stay abreast of the latest advancements and trends.
ANTIBACTERIAL SCREENING OF SARGASSUM SP EXTRACT. OPPOSING VIBRIO PARAHAEMOLYTICUS BACTERIA
Authors: Datu Syeiqido Sora , Angraeni  , Fatwasari Fina , Jarir Dewi Virgiastuti , Sabilah Anisa Aulia
Published: March 2024

Antibiotics cause resistance to pathogenic bacteria, and the emergence of resistance and bacterial pathogenic infections makes scientists try to find new drugs. One of the efforts is to use marine organisms as a natural antibacterial agent, one of them is Sargassum sp. Sargassum sp contains alginate and iodine which are used in the food, pharmaceutical, cosmetic and textile industries. Apart from that, Sargassum sp. contains active compounds of steroids, alkaloids, phenols and triterpenoids which function as antibacterials, can be used to inhibit the growth of Vibrio sp bacteria which is the cause of firefly disease which is most dangerous for tiger prawns. The purpose of this study was to determine the ability of the extract Sargassum sp. In inhibiting the growth of Vibrio parahaemolyticus bacteria with different levels of solvent start with methanol, ethyl asetat, and n-hexane. The rejuvenation of Vibrio parahaemolyticus and Vibrio harveyimelalai bacteria is carried out in two stages, the first is planting on Triptyc Soy Broth (TSB) medium and the second stage is planting on Triptyc Soy Agar (TSA) medium.  Antibacterial sensitivity test using disc diffusion method. The results of the test showed that 1). sargassum sp which is extracted by metanol solvent inhibits the growth of Vibrio parahemolyticus bacteria. 2). sargassum sp which extract by etil sestat and n - heksan solvent can't inhibit the Vibrio parahemolyticus bacteria.
Applying IROC Method in Patent Submission Evaluation in Indonesia: A Comparison with MAGIQ and AHP
Authors: Ambarsari Erlin Windia , Rahman Vierhan , Cholifah Wahyu Nur
Published: March 2024

This study applies the Improved Rank Order Centroid (IROC) to the Indonesian patent submission process within a Multi-Criteria Decision Making (MCDM) framework. The study evaluates four primary elements in patent assessment: "Patent Description," "Illustration," "Inventor's Ownership Statement," and "Rights Assignment Declaration." Preliminary findings indicate the importance of "Patent Description," followed by the other elements in descending order of significance. The evaluation also encompasses three applicant alternatives, with the Second Applicant emerging as the most favorable. The study further contrasts IROC outcomes with MAGIQ and AHP methodologies. While rank-based techniques like ROC and IROC generally produce similar weight distributions, the AHP method, which employs pairwise comparisons, often displays variations. The research underscores the potential of IROC in determining criterion weights, its comparison within the MAGIQ framework, and its validation through AHP. These insights aim to deepen our understanding of decision-making processes and analysis. The conclusion from comparing IROC results with MAGIQ and AHP indicates that the applicant rankings remain consistent. Therefore, further research is needed to understand the differences between evaluation methods and their impacts and explore the influence of cultural or regional factors in the patent submission process
Control de calidad fisicoquímico de inyectables endovenosos de nitroglicerina comercializados en el mercado argentino (mayo-diciembre 2022)
Authors: Saratsian Ana K. , Rabahia Christian J. , Maffeis Luis E. , Saint Martin Eduardo E. , Llauró Verónica S. , Rodríguez Yanina I.
Published: March 2024

La Dirección de Fiscalización y Gestión de Riesgo (INAME-ANMAT), a través del Departamento de Laboratorio Nacional de Control(LNC), diseña planes de trabajo anuales que incluyen muestreos de medicamentos para controlar la calidad de los productos de sucompetencia. Los criterios para ejecutar un Plan de Muestreo de los inyectables endovenosos de nitroglicerina fueron, por un lado,el antecedente de una notificación al Sistema Nacional de Farmacovigilancia por falta de efectividad en un lote de un producto y, por otro lado, la indicación como agente antianginoso en afecciones cardiovasculares (por ejemplo, angina de pecho) cuyo número lidera los casos de muertes en la República Argentina. El objetivo de este trabajo fue llevar a cabo el control de calidad de las especialidades medicinales autorizadas y comercializadas en nuestro país durante los meses de mayo a diciembre de 2022. La metodología utilizada fue “Nitroglicerina, Inyección” (USP 44) que utiliza cromatografía líquida de alta resolución (HPLC) con detector ultravioleta (UV) para la valoración. La verificación de la metodología fue realizada en cuanto a especificidad frente a placebos y recuperación, estabilidad de la solución estándar y aptitud de sistema, los cuales cumplieron con sus especificaciones. La totalidad de los lotes muestreados cumplieron con los ensayos de identificación y valoración. El control, la fiscalización y la vigilancia de los medicamentos realizados en el presente trabajo son un aporte a la evaluación de la seguridad, calidad y eficacia de los productos para la salud, la cual constituye la misión de ANMAT.
Towards Sustainable Nigerian Architectural Education
Authors: Ebelechukwu Obianuju Enwerekowe  , John Doyle  , Ifeoluwa Adebola Adetula
Published: March 2024

Architectural education comes from a long tradition of technical and artistic apprenticeship which is evolving in Nigeria and around the world. The aim of this study is to examine the relationship between design education (what), learning styles (how) and personality types (who) in a bid to develop sustainable, inclusive teaching strategies for the 21st century and beyond. The quantitative study assessed the preferred learning styles and predisposition for the five genetic personality traits in students of Architecture at the University of Jos, and juxtaposed the findings against their performance in design studio. The study findings showed that Accommodators and Divergers who were the highest performers in design studio were also the more likely to exhibit openness and conscientiousness. Convergers were more willing to accept criticism from their mentors and peers, and Assimilators were more prone to neurosis displayed as fear of disappointment and anxiety when they performed lower than their contemporaries. The study findings encourage continued monitoring of evolving teaching and learning styles, as well as cognisance of students' distinctive personality types to guide educators in developing teaching modules and methods that will be enduring and effective for holistic architectural education.
Penser les futurs noirs à travers le marronnage
Authors: Jean Lourdenie
Published: March 2024

Dans son texte Penser les futurs noirs à travers le marronnage, Lourdenie Jean propose le marronnage comme piste pour éclairer des questions face au futur, en soulever d’autres et tenter des réponses. Pour ce faire, elle distinguera deux schémas de marronnage, soient le marronnage de fuite et le marronnage collectif, par l'importance accordée aux garanties de sécurité. Pour finir, elle nommera l'importance de renforcer les imaginaires afros à travers la fiction pour mieux se projeter dans l'avenir.
Valoración del programa de socialización para fortalecer la convivencia escolar en estudiantes de educación básica.
Authors: Bravo Zambonino José María
Published: March 2024

School coexistence is one of the fundamental aspects for the well-being of the members of an educational community; its proper management allows improving academic performance and strengthening the quality of learning. For this reason, the design of a socialization program to strengthen school coexistence in fifth-year basic education students of the Ana Páez Educational Unit is proposed as a research objective. Regarding the methodology, the study responds to a mixed research design, the inductive method was used and the level of the study was descriptive and applied to the students to provide solutions for a healthy coexistence. The proposal was put into practice achieving great success in the student community.
Confiabilidad en el rendimiento de las máquinas de producción gracias al plan de mantenimiento preventivo
Authors: Ninatanta Medina Yahaira Jamileth , Vásquez Tejada Yanelia
Published: March 2024

Corporate preventive maintenance is performed proactively to address production problems before they happen, avoiding process inefficiencies and unexpected repairs. Being able to implement this strategy in a timely and routine manner brings benefits such as: assurance of production capacity; increased availability and useful life of equipment; safety for employees, cost savings and maximum efficiency. The objective of this research was to determine the influence of a preventive maintenance plan on the reliability of the production machines of Molino San Francisco S.A.C.; for this purpose, a descriptive-correlational research with a mixed design was carried out. The results of the research showed that the initial reliability obtained was 0.72 and with the implementation of the plan it was optimized to 0.85, evidencing that with the application of a correct preventive maintenance plan the reliability was significantly improved.
Prévalence de l'inclusion des dents de sagesse: étude radiologique auprès d'une population nord africaine
Authors: Yacoub Sinda , Dammak Nouha , Zaalouni Soumaya , Hrizi Mohamed Amine , Ben Khelifa Mohamed
Published: March 2024

Objectif : Déterminer la prévalence et les propriétés d’inclusion des dents de sagesses (M3M) et les pathologies qui lui sont associées chez une population Tunisienne.
Méthodes : Nous avons revu 730  panoramiques, parmi 6043 patients. Les informations suivantes ont été évaluées : la présence, l'angulation, la profondeur d'inclusion et les pathologies identifiées radiologiquement au niveau des dents de sagesse et des molaires adjacentes.
Résultats : Parmi les 730 patients, 367 (50,3%) ont présenté au moins une dent de sagesse incluse. La prévalence d’inclusion diminuait avec l'augmentation de l'âge. Le nombre total des dents de sagesses incluses était 881. Le nombre d’inclusions le plus frequent par patient était deux (35,7%). Le niveau d'inclusion le plus frequent au maxillaire était le niveau C et à la mandibule, le niveau A. L'angulation la plus fréquente était la verticale au maxillaire et à la mandibule. La plupart des M3M mandibulaires (76%) ont présenté la classe II en relation avec le ramus mandibulaire. 1,36% des deuxièmes molaires adjacentes à une dent de sagesse incluse ont montré une résorption radiculaire et 3,79% des M3M présentaient une pericoronite. 12,5% et 92,3% des deuxièmes molaires présentant des caries cervicales distales (DCC), respectivement au maxillaire et à la mandibule, sont adjacentes à dent de sagesse incluse. Les pathologies les plus associées aux dents de sagesse incluses étaient les caries distales des secondes molaires (11,7%) et les caries des  troisièmes molaires (5,2%).
Conclusion : L’inclusion des dents de sagesse était observée chez 50,3% d'un groupe....( résumé tronqué à 250 mots)
Les cytopénies auto-immunes de l’enfant : Quand penser au déficit immunitaire primitif ?
Authors: Hbibi Mohamed , El Alaoui El Hanafi Mounira , Kasmi Zakaria , Ouair Hind , Benmiloud Sarra , Ailal Fatima , Hida Moustapha , Bousfiha Ahmed Aziz
Published: March 2024

Les cytopénies auto-immunes se définissent par une destruction immunologique d’un ou plusieurs éléments figurés du sang par des auto-anticorps. Le plus souvent il s’agit d’une anémie hémolytique ou une thrombopénie immunologique ou les deux à la fois définissant un syndrome d’Evans. Chez l’enfant la cytopénie auto-immune peut être secondaire à une infection ou être inaugurale à une pathologie sous-jacente comme une maladie auto-immune systémique ou une immunodéficience primitive en particulier quand elle devient chronique sur plusieurs années.
 
Les déficits immunitaires primitifs ou erreurs innées de l'immunité (IEI) ne sont plus définis uniquement par les infections : l'auto-immunité fait partie du tableau clinique de plusieurs de ces maladies et est dominée par les cytopénies auto-immunes, en particulier, le purpura thrombopénique immunologique (PTI) et les anémies hémolytiques auto-immunes (AHAI).
 
Les problématiques que peut confronter le clinicien sont les situations ou les cytopénies auto-immunes sont chronique, récidivantes et ou réfractaires aux différents moyens thérapeutiques au long cours dont l’action le plus souvent est similaire et consiste généralement en une suppression ou une modulation immunitaire non spécifique, ce qui complique la prise en charge, malgré le panel hétérogène des traitements. Dans ces situations les déficit immunitaires primitifs doivent être diagnostiqués le plus tôt possible pour permettre l'initiation d'un traitement ciblé et éviter plusieurs lignes thérapeutiques inefficaces.
The effects of high-intensity interval training and iranian propolis extract on serum levels of TRPV4 and CYP2E1 proteins in patients with nonalcoholic fatty liver
Authors: Irandoust Khadijeh , Gholamhosseini Mahsa , Samimi Rasool , Dergaa Ismail , Ben Saad Helmi , Taher Mortez
Published: March 2024

Introduction. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver failure, fibrosis, cirrhosis, and liver cancer, which can eventually lead to death.
Aim. To investigate the effects of high-intensity interval training (HIIT) and iranian propolis extract on serum levels of transient receptor potential cation channel subfamily V member 4 (TRPV4) and cytochrome P450 2E1 (CYP2E1) proteins in patients with NAFLD.
Methods. Thirty-two patients with NAFLD (mean±standard deviation of age: 45.1±3.6 years; body mass index: 30.0±3.6 kg/m2) were assigned in a randomized control trial to one of the following groups: HIIT (n=8), propolis supplement (n=8), propolis + HIIT (n=8), and controls (n=8). The subjects participated in eight weeks of HIIT (one bout of 1-min intervals at 80-95% of the maximal heart-rate, interspersed by two min at 50-55% of the reserve heart-rate). The Propolis supplement was taken three times a day by the patients in the form of 50 mg tablet after the main meals. Body composition, liver injury test (eg; Alanine- and Aspartate- aminotransferase levels), liver ultrasound and serum levels of TRPV4 and CYP2E1 were measured before and after intervention. One-way analysis of variance was used to compare post-tests among the groups.
Results. HIIT significantly reduced serum levels of TRPV4 protein (p=0.001). The reduction in CYP2E1 was not significant in HIIT group (p=0.075). Propolis consumption had no significant effect on serum levels of CYP2E1 protein (p=0.059), and TRPV4 (p=0.072). There was a significant decrease in TRPV4 and CYP2E1 in the HIIT (p=0.001) .... (abstract truncated at 250 words).
Asociación de lumbalgia crónica con ansiedad en trabajadores de una Unidad de Medicina Familiar de Mexicali, Baja California. México
Authors: Villar Quintero Alva Daniela , García Ontiveros Blanca Evelia , Haro Acosta María Elena , Ayala Figueroa Rafael Iván
Published: March 2024

Objetivo: Determinar la asociación entre ansiedad y lumbalgia crónica en trabajadores. Métodos: Estudio descriptivo y transversal en 276 trabajadores de 35 a 50 años de edad con lumbalgia crónica de la Unidad de Medicina Familiar No. 16 de Mexicali, Baja California, Instituto Mexicano del Seguro Social. Se aplicó el cuestionario de Ansiedad de Hamilton durante el año 2022. Muestreo probabilístico, el tamaño de la muestra se realizó con la fórmula de proporciones con una confiabilidad del 95% siendo la muestra necesaria de 270 pacientes con diagnóstico de lumbalgia crónica. Resultados: La frecuencia de ansiedad en trabajadores fue del 75.3%; el 58.3% presentaron ansiedad leve y el 17% ansiedad moderada a grave. Se asoció la lumbalgia crónica (dolor por radiculopatía y dolor inespecífico) con la ansiedad (p=0,0001) sin considerar dos casos de dolor por enfermedad sistémica. Predominó la obesidad en el 54.7 % y el cuadro de lumbalgia crónica menor a un año. Conclusiones: El grado de ansiedad se asocia con la lumbalgia crónica. La frecuencia de ansiedad en trabajadores con lumbalgia crónica fue alta. La obesidad pudiera ser una posible causa para la exacerbación del dolor en estos pacientes.
Artificial Intelligence and Machine Learning for Green Shipping: Navigating towards Sustainable Maritime Practices
Authors: Nguyen Hoang Phuong , Nguyen Cao Thao Uyen , Tran Thi Men , Dang Quoc Hai , Pham Nguyen Dang Khoa
Published: March 2024

This paper aims to investigate the role that artificial intelligence (AI) plays in promoting sustainability in the marine industry. The report demonstrates the potential of AI-driven technology to improve vessel operations, decrease emissions, and promote environmental stewardship. This potential is shown by detailed examination of existing trends, problems, and possibilities. Several vital studies highlight the significance of policy interventions that encourage the use of artificial intelligence. These interventions include financial incentives, legal frameworks, and programs to increase capability. Throughout this work, the importance of the role that artificial intelligence plays in driving efficiency, safety, and sustainability is emphasized. This work also highlights the urgent need for action to address climate change and environmental degradation in the marine sector. The marine industry can lessen its carbon footprint, decrease pollution, and improve ecosystem health if it shifts to various alternative fuels, renewable energy sources, and technologies powered by artificial intelligence. At the end of this work, an appeal is made to policymakers, industry stakeholders, and technology providers, urging them to prioritize investments in artificial intelligence research and development and to create collaboration to speed up the transition to a marine sector that is more sustainable and resilient.
Main Switch Board Plan Maintenance System on MV. Kirana III
Authors: Nugroho Pasadhena Arief Cahya , Wiweko Albert , Siregar Muhammad Sapril
Published: March 2024

The Plan Maintenance System (PMS) is a continuous and scheduled maintenance system for equipment and supplies on a ship. Its purpose is to ensure that the ship is always in a seaworthy condition and ready to operate. In order to achieve smooth operation of the ship, it is essential to have a good, efficient, and effective work and maintenance system for the ship's electricity and systems. One way to do this is by formulating and implementing maintenance system plans by shipping companies in Indonesia. During research carried out on the KM Ship, KIRANA, it was found that there was a lack of maintenance on the Main Switch Board, leading to problems with the indicator lights and needles. Infrequent maintenance was also ignored, leading to undesirable events due to inadequate implementation of the planned maintenance system. To avoid damage or short circuits, it is important to schedule and regularly check the components of the switch board weekly and monthly. This will help maintain the components and minimize malfunctions on the switch board, with the help of scheduling in the Plan Maintenance System.
Pelaksanaan Sidang Elektronik dalam Penegakan Hukum Pidana di Pengadilan Negeri Bale Bandung Kelas 1A
Authors: Maryamah Mery , Azzahra Alviyanti , Rayhan Firza Muhamad , Ratnawidiastuti Eka , Prasetyo Catur , Trisnila Firlana
Published: March 2024

Persidangan perkara pidana di Pengadilan Negeri Bale Bandung Kelas 1A  sejak pandemi Covid-19 dilaksanakan secara Elektronik, yang diatur melalui Peraturan Mahkamah Agung Nomor 4 Tahun 2020 tentang Administrasi dan Persidangan Perkara Pidana di Pengadilan Secara Elektronik yang selanjutnya telah diperbaharui dengan Peraturan Mahkamah Agung Nomor 8 Tahun 2022 tentang Perubahan Atas Peraturan Mahkamah Agung Nomor 4 Tahun 2020 dan telah dikeluarkan Keputusan Ketua Mahkamah Agung Republik Indonesia Nomor 365/KMA/SK/XII/2022 tentang Petunjuk Teknis Administrasi dan Persidangan Perkara Pidana di Pengadilan Secara Elektronik. Saat dilakukan persidangan secara elektonik ini, untuk posisi para pihak didalam ruang persidangan pengadilan ialah Hakim, Jaksa Penuntut Umum di Kantor Kejaksaan, terdakwa di Rutan / LAPAS atau tempat lain yang ditetapkan oleh Majelis Hakim. Dalam hal pelaksanaan di Rutan / LPKA atau LAPAS, terdakwa menggunakan media video call yang telah disediakan oleh pihak LPKA/ RUTAN.  Sejauh ini kendala dalam pelaksanaan persidangan perkara pidana secara elektronik di Pengadilan Negeri Bale Bandung Kelas 1A adalah sarana prasarana, akses internet, pemenuhan hak terdakwa dan penerapan asas Sistem Peradilan Pidana.  Penelitian ini bertujuan untuk mengetahui bagaimana pelaksanaan Persidangan secara elektronik dalam penyelesaian perkara Pidana, hambatan serta efektifitas persidangan secara elektronik di Pengadilan Negeri Bale Bandung Kelas 1A.
Rancang Bangun Website Sekolah Dengan Menggunakan Bootsrap (Studi Kasus SMP Negeri 3 Pacet)
Authors: Sopandi Hendra , Senubekti Mamok Andri , Dewi Lies Anggi Puspita
Published: March 2024

Berkembangnya era teknologi data informasi saat ini berdampak pada kebutuhan akan informasi di setiap aspek kehidupan masyarakat. Salah satunya dalam aspek pendikakan. Seperti halnya yang terjadi pada SMPN 3 Pacet, pemanfaatan teknologi informasi belum dimanfaatkan seefektif mungkin. Dimana penyebaran sistem informasi tentang profil sekolah dan segala informasi sekolah yang ada saat ini masih bersifat manual yaitu menggunakan spanduk, papan pengumuman dan surat maupun mulut kemulut. Secara tidak langsung hal tersebut menjadi salah satu kendala dalam meningkatkan mutu dan kualitas pendidikan di SMPN 3 Pacet sebagai salah satu contoh Sekolah Menengah Pertama Negri di Bandung. Praktek Kerja Lapangan ini bertujuan untuk menghasilkan website tentang profil SMPN 3 Pacet. Metode penelitian yang penulis pergunakan adalah metode observasi, wawancara, kepustakaan, dan metode waterfall sebagai metode pengembangan sistem. Dengan adanya profil sekolah ini diharapkan akan memberikan kemudahan kepada masyarakat dalam mendapatkan informasi tentang SMPN 3 Pacet. Adapun sistem yang digunakan dalam pembuatan website ini adalah bahasa pemrograman PHP, database MySQL dan Bootstrap agar tampilan lebih menarik dan responsive. Sehingga dapat dimanfaatkan oleh masyarakat yang ingin mencari informasi seputar SMPN 3 Pacet tanpa harus datang ke sekolah. selanjutnya dengan adanya website profile tersebut, kesalahan-kesalahan dalam penyampaian informasi akan lebih mudah diperbaiki
Quines runes ens esperen. Tres filosofies de la ruïna a Walter Benjamin
Authors: Montull Lluís
Published: March 2024

Aquest assaig parteix de la crítica de Bruno Latour a la conferència L’estat de la naturalesa a l’àngel de la història benjaminià per la seva ceguesa davant de les runes que ens venen del futur en forma de catàstrofe climàtica i planetària. A partir d’aquí, es pregunta si des de la filosofia rememorativa de Walter Benjamin es pot respondre aquest no-futur i com fer-ho. Abordant la qüestió a partir de tres moments de la seva filosofia de la runa: el que té lloc en la incipient filosofia de joventut i els dos que giren respectivament entorn de l’al·legoria barroca i la imatge dialèctica. Un recorregut en què la runa apareix no només com a signe definidor de l’edat moderna i la modernitat, malgrat les seves pretensions contràries, sinó també com a manera de resistència que permeti albirar un futur plantejat no com a un progrés sense aturador, sinó com a interrupció de la catàstrofe a què aquest ens ha abocat. Aquest trajecte també vol ressaltar l’especificitat d’una figura fonamental a les Tesis com el «materialista històric» i, igualment, obrir preguntes sobre l’experiència filosòfica, la praxi científica o l’agència política dels morts, i del dany que donàvem per conclòs a l’era del capitalocè.
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1
Authors: Honzejkova Karolina , Košek Dalibor , Obsilova Veronika , Obsil Tomas
Published: March 2024

Apoptosis signal-regulating kinase 1 (ASK1) is a crucial stress sensor, directing cells towards apoptosis, differentiation and senescence via the p38 and JNK signaling pathways. ASK1 dysregulation has been associated with cancer and inflammatory, cardiovascular and neurodegenerative diseases, among others. However, our limited knowledge of the underlying structural mechanism of ASK1 regulation hampers our ability to target this member of the MAP3K protein family towards developing therapeutic interventions for these disorders. Nevertheless, as a multidomain Ser/Thr protein kinase, ASK1 is regulated by a complex mechanism involving dimerization and interactions with several other proteins, including thioredoxin 1 (TRX1). Thus, the present study aims at structurally characterizing ASK1 and its complex with TRX1 using several biophysical techniques. As shown by cryo-EM analysis, in a state close to its active form, ASK1 is a compact and asymmetric dimer, which enables extensive interdomain and interchain interactions. These interactions stabilize the active conformation of the ASK1 kinase domain. In turn, TRX1 functions as a negative allosteric effector of ASK1, modifying the structure of the TRX1-binding domain and changing its interaction with the tetratricopeptide repeats domain. Consequently, TRX1 reduces access to the activation segment of the kinase domain. Overall, our findings not only clarify the role of ASK1 dimerization and inter-domain contacts but also provide key mechanistic insights into its regulation, thereby highlighting the potential of ASK1 protein-protein interactions as targets for antiinflammatory therapy.
Capturing the unpredictability of stem cells
Authors: Durmaz Arda , Visconte Valeria
Published: March 2024

A new mathematical model that can be applied to both single-cell and bulk DNA sequencing data sheds light on the processes governing population dynamics in stem cells.
Tracking mosquito-borne diseases via social media: a machine learning approach to topic modelling and sentiment analysis
Authors: Ong Song-Quan , Ahmad Hamdan
Published: March 2024

Mosquito-borne diseases (MBDs) are a major threat worldwide, and public consultation on these diseases is critical to disease control decision-making. However, traditional public surveys are time-consuming and labor-intensive and do not allow for timely decision-making. Recent studies have explored text analytic approaches to elicit public comments from social media for public health. Therefore, this study aims to demonstrate a text analytics pipeline to identify the MBD topics that were discussed on Twitter and significantly influenced public opinion. A total of 25,000 tweets were retrieved from Twitter, topics were modelled using LDA and sentiment polarities were calculated using the VADER model. After data cleaning, we obtained a total of 6,243 tweets, which we were able to process with the feature selection algorithms. Boruta was used as a feature selection algorithm to determine the importance of topics to public opinion. The result was validated using multinomial logistic regression (MLR) performance and expert judgement. Important issues such as breeding sites, mosquito control, impact/funding, time of year, other diseases with similar symptoms, mosquito-human interaction and biomarkers for diagnosis were identified by both LDA and experts. The MLR result shows that the topics selected by LASSO perform significantly better than the other algorithms, and the experts further justify the topics in the discussion.
The Quality of Spent Hen Chicken Sausage with Tomato Paste at Different Refrigerated Storage Time
Authors: Anisa Cintya Dienardila , Evanuarini Herly , Amertaningtyas Dedes
Published: March 2024

Aims: This research aims to determine the quality of spent hen chicken sausage with the tomato paste at different refrigerated storage time based on pH, color, moisture content, total microorganism, and rancidity

Study Design: This research are an laboratory experimental with a completely randomized design.

Place and Duration of Study: This research are located in Laboratory of Animal Product Technology, Faculty of Animal Science, University of Brawijaya.

Methodology: This research are using a 4 treatments and 5 replications. The main focus are a different storage time for spent hen chicken sausage on refrigerator (4˚C). The 4 treatments are 0 day (D0), 7 days (D1), 14 days (D2), and 21 days (D3)

Results: The different storage time on spent hen sausage with tomato paste gave a very significant effect (P < .01) on pH, color analysis (L a*b*), moisture content, total microorganism, and rancidity. pH, moisture content, total microorganism, and rancidity are increased during storage time meanwhile for color analysis are decreased during storage time.

Conclusion: Except for being a natural food colorant, tomato can be used for natural antioxidant. The addition of tomato paste on spent hen sausage can extend spent hen sausage’s shelf life until 21 days on refrigerated temperature (4˚C). The further research are needed for consumer safety on spent hen chicken sausage with the addition of tomato paste.
Assessment of Seagrass Ecosystems’ Goods and Services of India
Authors: Ramesh D. Asir , Narayanan Dhivya , Karthi N. , Infantina Amali , Parasuram Priya
Published: March 2024

Nearly every shallow coastal region on Earth is home to seagrass, a type of marine flowering plant. They grow down to depths where just 11% of surface light reaches the bottom after colonizing soft substrates like mud, sand, and cobbles. Seagrasses often choose wave-sheltered environments where sediments are shielded from waves and currents. The seagrass environment serves as a home to large animals like dugongs and marine mammals like ducks and geese. The seagrass serves as a feeding and refuge area for the related creatures for the entirety or a portion of their life cycles. Raw materials and food, medicine, fertilizer, coastal protection, erosion control, water purification, fisheries maintenance, nursery grounds, invertebrate habitats, carbon sequestration, tourism, recreation, support for education, and research are just a few of the goods and services provided by seagrass to the coastal community. The value of a seagrass ecosystem's products and services to human well-being can be measured, and this can be used to support the need for seagrass ecosystem preservation, transfer, and regeneration. Many valuation studies are conducted to estimate the various goods and services produced by the seagrass ecosystem. The total area of seagrass distribution in the coastal States and UTs of India is 51822 ha, distributed in 4162 seagrass patches. Using meta-analysis and an average of Benefit Transfer (BT) method, the Total Economic Value (TEV) of seagrass has been estimated as Rs. 2594342/ha/yr. ($ 55,637/ha/yr.) with a maximum of Rs. 5948650 ha/yr. ($1,27,571/ha/yr.) and a minimum of 791448/ha/yr. ($ 16,973/ha/yr.). Subsequently, the total equivalent economic benefit from seagrass beds in India has been quantified at Rs.13444 crore/yr. ($ 2,88,31,22,453/yr.).
Smart and Sustainable City Experience on Smart Campus: A Case Study from Hassan Ist University
Authors: Malki Doha
Published: March 2024

The desire to meet the demands of regional competition requires cities to adopt new patterns of urban management. In this sense, the trend at the global level is to use smart city standards by investing in the digital transformation of various public services in cities. In recent years, many efforts have been made in many Moroccan cities to improve their attractiveness by being part of the process of upgrading and enhancing their territories through the implementation of major infrastructure projects and the digitalization of urban administrations.

This study was conducted to examine the feasibility of a smart campus as a discounted smart city, and it relies on the dissemination of a quantitative survey, via a questionnaire (live and online), supplemented by a qualitative survey based on focus group methodology. We have gained a broader perspective that allowed us to understand the reality of things on campus. The study also showed that there are many efforts that the university must take in conjunction with developing its plan to advance Hassan I University to the ranks of smart universities.

This article is part of a study proposing a strategy for developing the campus of Hassan I University of Settat to be a smart one.
Evaluation of the Effects of Drip Irrigation and Fertigation scheduling on Tomato Yield under Polyhouse
Authors: Singh Harmanpreet , Singh Jaspreet , Sandal Sanjeev K
Published: March 2024

In Northwestern Himalayas, there is scarcity of water owing to rugged terrain which results in lower tomato yield. Therefore to enhance the productivity of tomato, the experiment was conducted to evaluate the effects of drip irrigation and nutrient schedules on soil water dynamics and productivity of tomato under polyhouse. The treatments consisted of three drip irrigation levels viz., I1 (Daily drip irrigation 2.0 litre/m2 once in a day during first two months and 4.0 litre/m2 thereafter), I2 (Daily drip irrigation 1.0 litre/m2 once in a day during first two months and 2.0 litre/m2 thereafter) and I3 (Daily drip irrigation twice a day with 6 hours interval at 1.0 litre/m2) and three nutrient schedules viz., NPK75 (75% of RDF, 25% applied as basal and 75% through fertigation at 15 days interval), NPK100 (100% of RDF, 25% applied as basal and 75% through fertigation at 7 days interval) and NPK150 (150% of RDF, 25% applied as basal and 75% through fertigation twice a week). The results showed that the soil moisture content and soil water stock was higher under I3 and I1 and lower under I2 treatments. The marketable yield (6.31 kg m-2), water use efficiency (WUE) (1.94 g m-2 mm-1) and NPK uptake was significantly higher in I2 than I1 and I3. Among nutrient schedules, marketable yield (6.53 kg m-2), WUE (1.94 g m-2 mm-1) and NPK uptake were significantly higher under NPK150 nutrient schedule than NPK100 and NPK75. The net returns (Rs. 230) and benefit:cost (B:C) (4.62) ratio was highest under I2NPK150 followed by I1NPK150 and lowest under I3NPK75. The study concluded that I2 (Daily drip irrigation 1.0 litre/m2 once in a day during first two months and 2.0 litre/m2 thereafter) and NPK150 (150% of RDF, 25% applied as basal and 75% through fertigation twice a week) was most remunerative combination due to higher marketable yield and water use efficiency under polyhouse.
IS COAL ABLE TO SHINE? THE ROLE OF LEGAM IN SUPPORTING COAL JEWELRY-BASED SOCIAL ENTREPRENEURSHIP
Authors: Priyatmoko Rakhman , Maulana Addin , Oktaviyanti Dini , Usman Yessy Febrina , Khoiriyani Fauziah
Published: March 2024

As coal mining activities ceased in Sawahlunto, tourism, and the creative industry emerged as alternative avenues for the city's development. Legam is a player in the creative industry, specifically in the fashion sub-sector, specializing in coal-based jewelry production, a material abundant in Sawahlunto. Employing a na­r­rative approach and conducting interview data collection, this research aimed to identify the role of Legam Jewelry in supporting social entrepreneurship. A social entrepreneurship approach served as the analytical fra­mework, considering Legam Jewelry's unique business operations. Differences in the locations of raw ma­te­rial sources, workers' residences, and the business owner's domicile increased operational costs. It was interesting to comprehend Legam's motivation for maintaining this location difference between Bandung and Sawahlunto. The research findings indicated that Legam aligned its business processes with social entre­pre­neurship ele­ments such as social value, civil society, innovation, and economic activities. Despite being deemed capable of fulfilling these social entrepreneurship elements, several critical points required attention in Legam's business processes. One such point related to the need for government support to facilitate physical exhibitions after the coronavirus disease (COVID-19) pandemic. In creating a massive social impact, efforts were necessary to en­courage the emergence of similar entrepreneurs in Sawahlunto and other regions.
GEN Z AND THE FUTURE OF BANKING: AN ANALYSIS OF DIGITAL BANKING ADOPTION
Authors: Rithmaya Chitra Laksmi , Ardianto Herwin , Sistiyarini Evi
Published: March 2024

In the era of digitalization, a digital bank was the development of banking services. Bank in­no­vation led to innovation in providing various alternative services and improved the ease of tran­sactions for digital banking applications. This study aimed to discuss how digital banks used service features using a modified UTAUT2 approach. The data used was that of respondents belonging to generation Z in Indonesia who used digital banking services on mobile devices. Data analysis was done using PLS-SEM. The findings demonstrated that performance expectancy was the highest va­riable determining behavioral intention and used behavior. Habit and trust on service provider also predicted intention, and facilitating conditions also had a direct effect on usage behavior when adopt­ing digital banking in generation Z. Surprisingly, effort expectancy, social influence, hedonic mo­ti­vation, price value, and trust in the internet did not have a significant relationship, for which some possible reasons were explained further. In this article, theoretical and practical implications were also discussed.