bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of the AMO and its modulation of the ENSO effects on summer precipitation in Mexican coastal regions
Authors: Rodríguez Morales Uxmal , Corona Vásquez Benito , Prieto González Ricardo , Martínez Austria Polioptro
Published: February 2023

Due to its geographical location and interaction with the two largest oceans, Mexico's climate is strongly influenced by various climatic oscillations. Therefore, association studies between climatic indices and Mexico's climate have scientific and practical importance. Teleconnection patterns have been reported between summer precipitation and various climate oscillations. For the AMO, results are not totally coincident, and modulation of ENSO effects has not been explored. Correlation analyses between AMO and ONI 3.4 with summer precipitation (June–September) at individual 203 weather stations in Mexican coastal zones were carried out, and average precipitation was compared according to AMO phases and their combinations with ENSO events. With AMO + , it tends to rain more in northern Yucatan Peninsula, from Chiapas to Jalisco, and in the southern California Peninsula; with AMO− in Tamaulipas, Sonora and northern California Peninsula. AMO modulates ENSO effects; ONI correlations pattern strengthens with AMO+. El Niño summers are less dry with AMO− on Atlantic coast, Sonora and northern California Peninsula; on Pacific coast, alternating bands are observed. With AMO − , La Niña summers tend to be wetter toward south with AMO+ and toward north with AMO−. These changes can be related to variations in the surface and low-level wind regimes previously reported in literature.
Spatial and temporal variabilities of suspended sediment and dissolved nutrients in the Ca River basin, North Central Vietnam
Authors: Phuong Ho Thi , Kim Thanh Ha Thi , Huu Le Tien , Saito Mitsuyo
Published: February 2023

The Ca River basin has an area of 27,200 km2 distributed across the territories of two countries: Vietnam (65.2%) and Lao (34.8%). Spatial and temporal variations in suspended sediment (SS) and dissolved nutrients (PO43-, NO3-, SiO2) were determined in two hydrological stations located along the Ca River 4–6 times per month in the rainy season and 1–4 times per month in the dry season, between the months of August 2017 and July 2018. A loading–discharge (L–Q) curve was used to analyze the correlation among water physicochemical parameters with seasonal river discharge. The results indicate that SS was higher in upstream flows compared to downstream flows, which is primarily due to erosion. Seasonal SS and dissolved phosphate have an inverse correlation trend to that of dissolved silica. Results revealed that the concentration of phosphate and SS was higher in the rainy season than in the dry season. This finding proves that rain washes particulate matter from the surface runoff into the Ca River. Significant correlations between discharge and dissolved nutrient load were observed. This study provides useful information regarding variations of SS and water physicochemical parameters with seasonal water discharge in the Ca River.
Is BMI Associated with COVID-19 Severity? A Retrospective Observational
Study
Authors: Candelli Marcello , Pignataro Giulia , Saviano Angela , Ojetti Veronica , Gabrielli Maurizio , Piccioni Andrea , Gullì Antonio , Antonelli Massimo , Gasbarrini Antonio , Franceschi Francesco
Published: February 2023

Background:

Coronavirus-19 disease (COVID-19) is an infection with high
morbidity and mortality. Obesity and low body mass index (BMI) have both been linked
to severe COVID-19, but recent studies have failed to confirm these associations.

Objectives:

The aim of this study was to examine the relationship between BMI and disease
progression in hospitalised patients with COVID-19.

Methods:

We performed a monocentric, retrospective observational study at the Fondazione
Policlinico Gemelli in Rome. We enrolled 1544 (977 men) patients who presented
to the emergency department with a positive COVID-19 test between January and December
2021. We divided patients into five classes based on BMI. Demographic, clinical,
laboratory, and radiological data were collected for all patients.

Results:

Of the 1544 patients, 1297 recovered after hospitalization, whereas 247 (16%)
died. Of those who died, 16/247 (6.5%) had a BMI below18.5 kg/m2, 72/247 (29%) had a
BMI between 18.5 and 24.99 kg/m2, 103/247 (42%) had a BMI between 25 and 29.99
kg/m2, 36/247 (15%) had a BMI between 30 and 35 kg/m2, and 20/247 (8%) had a BMI
above 35 kg/m2. After adjusting the results for age, sex, and concomitant diseases using
multivariate logistic regression, we found a significantly increased risk of intensive care
unit (ICU) admission in severely obese patients (BMI > 35) compared to normal weight
patients (BMI: 18.5-24.99) (p > 0.001). Mortality was not associated with BMI.

Conclusion:

We confirm that severe obesity is a risk factor for ICU admission in patients
with COVID-19. No association was found between BMI and mortality.
One-Step, Low-Cost, Operator-Friendly, and Scalable Procedure to Synthetize Novel
Tetrazolopyrimidinylbenzopyran-2-ones by Benign Protocol
Authors: Ahmed Eman A. , Khodairy Ahmed , Abd El Aleem Ali Ali El-Remaily Mahmoud , Ahmed Abdelraheem M.
Published: February 2023

New coumarin chalcones 3j–p were conveniently obtained in high yields via Claisen-Schmidt condensation reaction, when acetyl coumarin 1 reacted with 3-aryl-1-phenyl pyrazole-4-carbaldehydes 2j–p in boiling ethanol in the presence of triethyl amine as a catalyst. Also, two synthetic pathways were afforded for the synthesis of novel tetrazolo[1,5-a]pyrimidinyl-2H-chromen-2-ones 5a-p. The first pathway is a multistep process including formation and separation of chalcones, which then were allowed to react with 5-aminotetrazole 4. While, the second pathway is a highly efficient one-pot three-component condensation reaction of 3-acetyl coumarin 1, aromatic aldehydes 2a-p and 5-aminotetrazole 4 under green and mild reaction conditions by using acetic acid (AcOH) as a catalyst and solvent. The molecular structure of products was established on the basis of their NMRs, IR and elemental analysis data. Solvent optimization was carried out in the reaction producing 3-(5-Phenyl-4,5-dihydrotetrazolo[1,5-a]pyrimidin-7-yl)-2H-chromen-2-one (5a). The advantages to using environmental-friendly acetic acid are simple operation, short reaction time, high efficient (97%), operationally facile and wide tolerance of starting materials.

objective:

The advantages of using environmental-friendly AcOH are simple operation, short reaction time, high efficient (97%), operationally facile and wide tolerance of starting materials.
Physiological Roles of Hippo Signaling Pathway and Autophagy in
Dementia
Authors: Christoper Andreas , Herman Herry , Abdulah Rizky , Zulhendri Felix , Sanjaya Ardo , Lesmana Ronny
Published: February 2023

Background:

Dementia is a neurocognitive disorder associated with the aging brain and
mainly affects the hippocampus and cerebral cortex. The Hippo signaling pathway and autophagy
proteins have been found to be perturbed in the brain affected by dementia processes.

Objective:

This systematic review aims to elaborate on the involvement of the Hippo signaling
pathway and autophagy in modulating the progression and severity of dementia in aging.

Methods:

Searches were conducted on MEDLINE, Google Scholar, Scopus, and Web of Science
databases.

Results:

The Hippo signaling pathway is dependent upon the transcriptional co-activator
YAP/TAZ, which forms complexes with TEAD in the nucleus in order to maintain cell homeostasis.
When the expression YAP/TAZ is reduced, transcriptional repression-induced atypical cell
death, ballooning cell death, and necrosis will consequently occur in the neurons. Moreover, the
autophagic proteins, such as LC3, ATG proteins, and Beclin, are reduced, resulting in the disruption
of autophagosome formation and accumulation and the spread of misfolded proteins in the brain
suffering from dementia.

Conclusion:

The impairment of the Hippo signaling pathway and autophagy in the dementia process
in aging should be considered since it might predict the severity, treatment, and prevention of
dementia.
Medicinal Plants used Traditionally in Sudan to Treat Viral Infections
Related to the Signs and Symptoms of COVID-19: A Systematic Review
Authors: Yagi Sakina , Yagi Ahmed
Published: February 2023

Background:

The rapid global spread of the COVID-19 pandemic urged scientists to
search for effective and safe anti-coronavirus drugs from natural resources. Through centuries, traditional
medicinal plants have been providing cure for diseases and general health care worldwide.

Objective:

The main aim of this review was to explore and summarize the research works on the different
plants used traditionally in Sudan to treat signs and symptoms of COVID-19 and respiratory diseases,
characterizing their antiviral activities and exploring the different phytochemicals present in these plants.

Method:

The current review was carried out in line with the recommendations of the PRISMA
2020 statement. Information on plants traditionally used in Sudan to treat the signs and symptoms
of COVID-19 and respiratory diseases was obtained from traditional medicine books and published
articles, as well as the daily practice by ordinary people.

Results:

This article illustrated the use of 27 plant species belonging to 15 families in Sudanese traditional
medicine to treat signs and symptoms of COVID-19 and respiratory diseases. Leguminosae/
Fabaceae was found to be the most represented family (7 species), followed by Combretaceae
(3 species) and Capparidaceae and Malvaceae (2 species each). From these plants, about 11 plant
species were studied for their antiviral activity against at least one virus, and 5 plants, namely Adansonia
digitata, Boscia senegalensis, Hibiscus sabdariffa, Nigella sativa, and Mangifera indica, were
tested for their antiviral activity against influenza viruses. The phytoconstituents of the listed plants
were summarized, and the antiviral activity of their isolated bioactive compounds was highlighted.

Conclusion:

The review could provide an in-depth theoretical basis and valuable data for designing
future studies.
Influence of User Profile Attributes on e-Cigarette–Related Searches on YouTube: Machine Learning Clustering and Classification
Authors: Murthy Dhiraj , Lee Juhan , Dashtian Hassan , Kong Grace
Published: February 2023

Background

The proliferation of e-cigarette content on YouTube is concerning because of its possible effect on youth use behaviors. YouTube has a personalized search and recommendation algorithm that derives attributes from a user’s profile, such as age and sex. However, little is known about whether e-cigarette content is shown differently based on user characteristics.

Objective

The aim of this study was to understand the influence of age and sex attributes of user profiles on e-cigarette–related YouTube search results.

Methods

We created 16 fictitious YouTube profiles with ages of 16 and 24 years, sex (female and male), and ethnicity/race to search for 18 e-cigarette–related search terms. We used unsupervised (k-means clustering and classification) and supervised (graph convolutional network) machine learning and network analysis to characterize the variation in the search results of each profile. We further examined whether user attributes may play a role in e-cigarette–related content exposure by using networks and degree centrality.

Results

We analyzed 4201 nonduplicate videos. Our k-means clustering suggested that the videos could be clustered into 3 categories. The graph convolutional network achieved high accuracy (0.72). Videos were classified based on content into 4 categories: product review (49.3%), health information (15.1%), instruction (26.9%), and other (8.5%). Underage users were exposed mostly to instructional videos (37.5%), with some indication that more female 16-year-old profiles were exposed to this content, while young adult age groups (24 years) were exposed mostly to product review videos (39.2%).

Conclusions

Our results indicate that demographic attributes factor into YouTube’s algorithmic systems in the context of e-cigarette–related queries on YouTube. Specifically, differences in the age and sex attributes of user profiles do result in variance in both the videos presented in YouTube search results as well as in the types of these videos. We find that underage profiles were exposed to e-cigarette content despite YouTube’s age-restriction policy that ostensibly prohibits certain e-cigarette content. Greater enforcement of policies to restrict youth access to e-cigarette content is needed.
Understanding Transgender and Gender-Diverse Youth’s Experiences Receiving Care via Telemedicine: Qualitative Interview Study
Authors: Kahn Nicole F , Anan Yomna H , Bocek Kevin M , Christakis Dimitri A , Richardson Laura P , Pratt Wanda , Sequeira Gina M
Published: February 2023

Background

Access to virtual care has increased since the beginning of the COVID-19 pandemic, yet little is known about transgender and gender-diverse (TGD) youth’s experiences and perspectives on receiving care via telemedicine.

Objective

The purpose of this study was to explore these experiences to (1) inform necessary changes to the provision of pediatric gender-affirming care and (2) help providers and health systems determine if and how telemedicine should be made available post pandemic.

Methods

Youth (aged 14-17 years) who completed a telemedicine visit in the Seattle Children’s Gender Clinic were invited to participate in a semistructured interview exploring perceived advantages or disadvantages of telemedicine and preferred visit modalities. Interview transcriptions were analyzed by 2 research team members using an inductive thematic analysis framework.

Results

A total of 15 TGD youth completed an interview. Commonly cited advantages of telemedicine were convenience and comfort with having visits in their own environments. Reported disadvantages included technical issues, discomfort with the impersonal nature, lack of familiarity with the platform, and privacy concerns. Overall, slightly more youth preferred in-person visits over telemedicine, referencing both specific characteristics of the clinical visit (ie, initial vs return and complexity) and proximity to the clinic as reasons for this preference. Although a plurality of TGD youth preferred in-person visits, they also recognized the value of telemedicine and the impact it may have in facilitating access to care.

Conclusions

Given the variations in needs and visit complexity, our study supports the provision of both in-person and telemedicine modalities as options for pediatric gender-affirming care.
A Relational Agent Intervention for Adolescents Seeking Mental Health Treatment: Protocol for a Randomized Controlled Trial
Authors: Chiauzzi Emil , Robinson Athena , Martin Kate , Petersen Carl , Wells Nicole , Williams Andre , Gleason Mary Margaret
Published: February 2023

Background

Unmet pediatric mental health (MH) needs are growing as rates of pediatric depression and anxiety dramatically increase. Access to care is limited by multiple factors, including a shortage of clinicians trained in developmentally specific, evidence-based services. Novel approaches to MH care delivery, including technology-leveraged and readily accessible options, need to be evaluated in service of expanding evidence-based services to youths and their families. Preliminary evidence supports the use of Woebot, a relational agent that digitally delivers guided cognitive behavioral therapy (CBT) through a mobile app, for adults with MH concerns. However, no studies have evaluated the feasibility and acceptability of such app-delivered relational agents specifically for adolescents with depression and/or anxiety within an outpatient MH clinic, nor compared them to other MH support services.

Objective

This paper describes the protocol for a randomized controlled trial evaluating the feasibility and acceptability of an investigational device, Woebot for Adolescents (W-GenZD), within an outpatient MH clinic for youths presenting with depression and/or anxiety. The study’s secondary aim will compare the clinical outcomes of self-reported depressive symptoms with W-GenZD and a telehealth-delivered CBT-based skills group (CBT-group). Tertiary aims will evaluate additional clinical outcomes and therapeutic alliance between adolescents in W-GenZD and the CBT-group.

Methods

Participants include youths aged 13-17 years with depression and/or anxiety seeking care from an outpatient MH clinic at a children’s hospital. Eligible youths will have no recent safety concerns or complex comorbid clinical diagnoses; have no concurrent individual therapy; and, if on medications, are on stable doses, based on clinical screening and as well as study-specific criteria.

Results

Recruitment began in May 2022. As of December 8, 2022, we have randomized 133 participants.

Conclusions

Establishing the feasibility and acceptability of W-GenZD within an outpatient MH clinical setting will add to the field’s current understanding of the utility and implementation considerations of this MH care service modality. The study will also evaluate the noninferiority of W-GenZD against the CBT-group. Findings may also have implications for patients, families, and providers looking for additional MH support options for adolescents seeking help for their depression and/or anxiety. Such options expand the menu of supports for youths with lower-intensity needs as well as possibly reduce waitlists and optimize clinician deployment toward more severe cases.

Trial Registration

ClinicalTrials.gov NCT05372913; https://clinicaltrials.gov/ct2/show/NCT05372913

International Registered Report Identifier (IRRID)

DERR1-10.2196/44940
Evaluation of Diversity Among Integrated Vascular Surgery Residency Programs: A Lens Through Their Public Websites (Preprint)
Authors: Treffalls Rebecca N , Prasla Sanaa , Hopper William , Yan Qi , Luu Jennie H , Davies Mark G
Published: February 2023

BACKGROUND

A diverse workforce is necessary to meet the needs of a diverse U.S. population. Objectively diverse residency programs are more likely to attract diverse applicants.

OBJECTIVE

This study assesses the evidence of diversity on integrated vascular residency program websites.

METHODS

The list of integrated vascular surgery residencies was obtained through the ACGME website. Each program website was evaluated for the presence of 8 elements: (1) nondiscrimination statement; (2) inclusion statement; (3) community demographics; (4) biographies of faculty; (5) biographies of residents; (6) headshots of faculty; (7) headshots of residents; and (8) listed resources available for trainees. Each element was awarded a score of 1 if an element was present, with a maximum total score of 8. We evaluated the relationship between the number of diversity elements with the program affiliation, city population size, region, program director gender, program director ethnicity, and program size.

RESULTS

A total of 65 ACGME-accredited integrated vascular residencies were identified. Of the 64 programs with websites, 77% had less than four diversity components, with the remaining 23% meeting a score of four or more. Most websites (83%) met at least 1 criterion; however, the median diversity element score was 3 (IQR 1-3). Six programs (9.4%) included a nondiscrimination statement and eight (12.5%) programs included inclusion statements. Nine programs (14%) included a community description, and 13 programs (20%) included resident resources. Faculty and resident biographies were included on 16% and 25% of websites, respectively. Faculty and resident photographs were the most common diversity elements on websites with frequencies of 69% and 72%, respectively. There was no difference in total diversity component score when stratified by city size, program size, program director gender, program director ethnicity, or affiliation.

CONCLUSIONS

Integrated vascular surgery residency programs globally failed to publicly demonstrate diversity across program websites. These results emphasize the importance for programs to demonstrate their commitment to diversity more effectively on their websites. The lack of diversity on program websites can be improved by including diversity and inclusion statements, photographs of faculty and residents, gender-inclusive material, and trainee resources.
Association Between Internet Searches Related to Suicide/Self-harm and Adolescent Suicide Death in South Korea in 2016-2020: Secondary Data Analysis (Preprint)
Authors: Choi Won-Seok , Han Junhee , Hong Hyun Ju
Published: February 2023

BACKGROUND

Previous studies have investigated the association between suicide and internet search volumes of terms related to suicide or self-harm. However, the results varied by people’s age, period, and country, and no study has exclusively investigated suicide or self-harm rates among adolescents.

OBJECTIVE

This study aims to determine the association between the internet search volumes of terms related to suicide/self-harm and the number of suicides among South Korean adolescents. We investigated gender differences in this association and the time lag between the internet search volumes of the terms and the connected suicide deaths.

METHODS

We selected 26 search terms related to suicide and self-harm among South Korean adolescents, and the search volumes of these terms for adolescents aged 13-18 years were obtained from the leading internet search engine in South Korea (Naver Datalab). A data set was constructed by combining data from Naver Datalab and the number of suicide deaths of adolescents on a daily basis from January 1, 2016, to December 31, 2020. Spearman rank correlation and multivariate Poisson regression analyses were performed to identify the association between the search volumes of the terms and the suicide deaths during that period. The time lag between suicide death and the increasing trend in the search volumes of the related terms was estimated from the cross-correlation coefficients.

RESULTS

Significant correlations were observed within the search volumes of the 26 terms related to suicide/self-harm. The internet search volumes of several terms were associated with the number of suicide deaths among South Korean adolescents, and this association differed by gender. The search volume for “dropout” showed a statistically significant correlation with the number of suicides in all adolescent population groups. The correlation between the internet search volume for “dropout” and the connected suicide deaths was the strongest for a time lag of 0 days. In females, self-harm and academic score showed significant associations with suicide deaths, but academic score showed a negative correlation, and the time lags with the strongest correlations were 0 and –11 days, respectively. In the total population, self-harm and suicide method were associated with the number of suicides, and the time lags with the strongest correlations were +7 and 0 days, respectively.

CONCLUSIONS

This study identifies a correlation between suicides and internet search volumes related to suicide/self-harm among South Korean adolescents, but the relatively weak correlation (incidence rate ratio 0.990-1.068) should be interpreted with caution.
Association Between the Loss of Gait Harmony and Cognitive Impairment: Cross-Sectional Study (Preprint)
Authors: Choi Ju-Young , Ha Sang-Won , Jeong Da-Eun , Lee Jaeho , Kim Donghoon , Min Jin-Young , Min Kyoung-Bok
Published: February 2023

BACKGROUND

Functional limitations and disabilities have been associated with a decrease in cognitive function due to increasing age. Gait performance and cognitive function have been associated with gait variability in executive function, the phase domain in memory, and gait abnormalities in cognitive decline.

OBJECTIVE

Our study aimed to investigate whether gait harmony was associated with cognitive function in the older adult population. Moreover, we aimed to investigate whether gait harmony was associated with cognitive function and explore each cognitive function in a specific harmonic state.

METHODS

The study population included 510 adults aged ≥60 years who visited the Department of Neurology at the Veterans Health Service Medical Center, Seoul, South Korea. Gait data were collected using a 3D motion capture device with a wireless inertial measurement unit system. For cognitive function assessments, we used the Seoul Neuropsychological Screening Battery-Core test, which evaluates the level of cognitive function or impairment in 5 cognitive domains.

RESULTS

In general, the association between the Seoul Neuropsychological Screening Battery-Core tests and the stance-to-swing ratio in the >1.63 ratio group yielded lower β coefficients than those in the 1.50-1.63 ratio group. After adjustment for confounders, the odds ratio (OR) for the Digit Symbol Coding test (adjusted OR 0.42, 95% CI 0.20-0.88) and the Korean version of the Color Word Stroop Test: 60 seconds (adjusted OR 0.51, 95% CI 0.29-0.89) for frontal and executive function were significantly lower for the >1.63 ratio group than the reference group.

CONCLUSIONS

Our findings suggest that the gait phase ratio is a valuable indicator of walking deficits and may also be associated with cognitive impairment in older adults.
Visual Analytics and Deep Mining of Multidimensional Oral Health Surveys (Preprint)
Authors: Zhou Zhiguang , Ma Yuming , Pan Tianya , Chen Yifei , Liu Yuhua , Zhu Fudong , Chen Qianming
Published: February 2023

BACKGROUND

Oral health surveys largely facilitate the prevention and treatment of oral diseases as well as the awareness of population health status. As oral health is always surveyed from a variety of perspectives, it is quite a difficult and complicated task to gain insights from multidimensional oral health surveys.

OBJECTIVE

In this paper, we develop a visualization framework for the visual analytics and deep mining of multidimensional oral health surveys.

METHODS

First, diseases and groups are embedded into data portraits based on their multidimensional attributes. Based on group classification, correlation patterns are then built for diseases, behaviors, symptoms and cognition to reveal their correlation features. Given the extricated knowledge of diseases, groups, behaviors and their attributes, a knowledge graph is further constructed to reveal semantic information, integrate the graph query function, and describe the features of intrigue to users.

RESULTS

A set of meaningful user interactions are integrated, enabling users to intuitively understand the oral health situation and conduct in-depth data exploration and analysis. Case studies based on real-world datasets and interviews with domain experts have demonstrated the effectiveness of our system.

CONCLUSIONS

In this paper, we propose a visualization framework for multidimensional oral health surveys. A series of user-friendly interactions are integrated to propose a visual analysis system that can help users further explore the regulations of oral health conditions. Case studies based on real-world datasets demonstrate the effectiveness of our system in the exploration of oral diseases.
Effect of Topography on the Heavy Metal Levels of Raphia Palm Tree and Oil Palm Tree Wine Produced within Awka South and North Local Government Areas in Anambra State
Authors: C.C. Aniobi , H.C. Okeke , O. Okeke , I.C. Akagha , C.N. Osueze , P.C. Ezeagwu
Published: February 2023

Studies were carried out to evaluate the effect of topography on the heavy metal levels of raphia palm tree and oil palm tree wine produced within Awka South and North local government areas using standard analytical procedures and instrumentation. Soil and palm (oil palm tree and raphia palm tree) wine samples produced in the studied upland and lowland areas were wet digested and analyzed for the presence of Pb, Cu, Cd and Zn using atomic absorption spectrophotometer.The lowland soil samples had 0.38±0.08, 6.27±0.40, 0.18±0.05 and 9.55±0.80µg/g as mean levels for Pb, Cu, Cd and Zn respectively. The upland soil samples had 0.70±0.04, 4.89±0.15, 0.06±0.02 and 7.07±0.22 µg/g as the mean levels for Pb, Cu, Cd and Zn respectively. The studied heavy metals were present in the soil sample areas in the following decreasing order; Zn > Cu >Pb >Cd.The mean range of Pb, Cu, Cd and Zn levels in the palm (oil palm tree and raphia palm tree) wine samples produced in the upland areas were 0.04- 0.06, 1.06- 1.91, 0.03- 0.05 and 2.86- 4.04 µg/g respectively. Pb was at toxic level in the oil palm tree wine samples produced in the upland areas.The mean range of Pb, Cu, Cd and Zn levels in the palm (oil palm tree and raphia palm tree) wine samples produced in the lowland areas were 0.05- 0.09, 1.95- 3.23, 0.04- 0.07 and 4.66- 6.51µg/g respectively. Pb, Cu and Cd were at toxic levels in the oil palm tree wine samples produced in the lowland areas. The palm wine samples produced in both the lowland and upland areas contained the investigated heavy metals at statistically significant levels. Because of the near daily consumption of palm wine produced from the oil palm and raphia trees as a drink of leisure by all categories of the people in the society, especially with high volume of production taking place in the lowland areas, it is important that human activities that supports the contamination of the soil with heavy metals, where these wines are produced are checkmated by government and host communities so as to limit the exposure to the heavy metals by palm wine consumers.
Comprehensive Review on Herbal or Medicated Toothpaste--A Review on Herbal v/s Medicated Toothpaste
Authors: Sohta Anchal , Kakar Satinder , Singh Ramandeep , Garg Urvashi
Published: February 2023

A dentifrices are the products which are used for oral hygiene such as freshness of mouth and to avoid tooth decay. The oral hygiene can be maintained throughout the day by using various dentifrices prepared by herbal and medicated ingredient. A tooth is small, calcified, whitish, structure found in the jaws of many vertebrates and used to breakdown food. Teeth are not made of bone but rather of multiple tissues of varying density and hardness. Dentifrices contain ingredients that help reduce caries, plaque, gingivitis, hypersensitivity, calculus, slain, halitosis. Herbal toothpaste where no chemicals, preservatives are added; instead glycerin and common salt are added as natural preservative. This toothpaste can cure various diseases as teeth like gingivitis, tooth decay, cavity, gum bleeding, bad breath and dental caries as well as it has antismoking and anti cancer properties. While medicated toothpaste is a type of toothpaste that applies a medicine to the teeth, gum and mouth. Some medicated toothpaste require pacific application technique or a set duration of contact with the teeth, gums and mouth in order to provide a medical benefit. As the name suggest, these toothpaste have some medicinal properties. They are created pacifically to help in solving an oral health issues.
Uji organoleptis kualitas teh berbahan dasar bunga belimbing wuluh
Authors: Sugiarmawan I Kadek Edi
Published: February 2023

Teh adalah suatu minuman yang memiliki rasa yang sangat spesifik dan sangat di minati oleh masyarakat Indonesia. Proses pembuatan teh ini menggunakan teknik penjemuran langsung dengan bantuan sinar matahari. Melihat pengolahan teh yang semakin maju namun kurangnya inovasi bahan lokal dalam pembuatannya, mendorong penulis untuk mencari bahan lokal pembuat teh yang dipandang sebelah mata namun memiliki banyak sekali khasiat yang sangat baik bagi tubuh manusia. Tujuan penelitian ini untuk mengetahui kualitas teh dari segi rasa, aroma, warna dan mengetahui berapa lama teh dapat disimpan atau dikonsumsi. Tempat penelitian ini berada di Mano Beach House, Jl. Pantai Pura Petitenget Krobokan Kelod, Seminyak, Kec, Kuta Utara, Kabupaten Badung, Bali. Penelitian akan dilakukan dari bulan Februari– Mei 2021. Metode yang digunakan dengan cara mengumpulkan data dengan kuisioner dan observasi. Teknik analisa data dengan menberikan kuisioner kepada 30 orang panelis dari segi rasa, aroma, dan warna. Berdasarkan hasil persentase data yang di ujikan kepada 30 panelis menyatakan 10% menyatakan sangat enak, 13% menyatakan cukup enak, 39% menyatakan cukup enak, 13% menyatakan tidak enak, 25% menyatakan kurang enak. Dan memiliki daya tahan selama 1 hari dihari ke 2 indikator rasa, warna, dan aroma menghilang.
 
Tea is a drink that has a very specific taste and is of great interest to the people of Indonesia. The process of making this tea uses direct drying techniques with the help of sunlight. Seeing the progress of tea processing but the lack of innovation from local ingredients in its manufacture, prompted the author to look for local tea-making ingredients that are underestimated but have many excellent properties for the human body. The purpose of this study was to determine the quality of tea in terms of taste, aroma, color and to find out how long tea can be stored or consumed. The place of this research is at Mano Beach House, Jl. Petitenget Krobokan Kelod Temple Beach, Seminyak, Kec, North Kuta, Badung Regency, Bali. The research will be conducted from February to May 2021. The method used is to collect data using questionnaires and observations. Data analysis technique by giving questionnaires to 30 panelists in terms of taste, aroma and color. Based on the results of the percentage of data tested on 30 panelists, 10% said it was very good, 13% said it was quite good, 39% said it was quite good, 13% said it was not good, 25% said it was not good. And it has a durability of 1 day on the 2nd day the taste, color and aroma indicators disappear.
Pemanfaatan buah nanas dalam pembuatan popcorn
Authors: Adithya Putu Bagus Roland
Published: February 2023

Popcron merupakan makanan ringan / snack siap saji yang pada umumnya dijual di pasaran yang dibuat dengan bahan dasar biji jagung olahan dengan varian rasa salty,karamel, keju dan coklat. Peneliti melakukan eksperimen dengan memanfaatkan buah nanas sebagai varian rasa dalam pembuatan popcorn. Penelitian dilaksanakan pada bulan mei 2021 hingga Agustus 2021. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana kualitas popcorn dengan rasa buah nanas dari segi rasa, aroma, tekstur dan warna. Dalam data ini menggunakan analisis uji organoleptik dengan responden sebanyak 30 responden. Hasil yang diperoleh yaitu dari segi warna popcorn rasa nanas mendapatkan skor sebesar 125 , dari segi rasa popcorn rasa nanas mendapatkan skor sebesar 122, dari segi aroma popcorn rasa nanas mendapatkan skor sebesar 124 dan dari segi tekstur popcorn rasa nanas mendapatkan skor sebesar 138. Untuk daya tahan popcorn rasa nanas dapat bertahan dalam suhu ruangan selama 2 hari saat sudah melalui proses memasak. Untuk biaya pembuatan popcorn dengan rasa buah nanas adalah sebesar Rp. 16.410 untuk pembuatan 1 box popcorn yang dapat menampung 100 gram popcorn
 
Popcron is a ready-to-eat snack / snack that is generally sold in the market which is made with the basic ingredients of processed corn kernels with variants of salty, caramel, cheese and chocolate flavors. Researchers conducted experiments by using pineapple as a flavor variant in making popcorn. The research was conducted from May 2021 to August 2021. The purpose of this study was to determine the quality of popcorn with pineapple flavor in terms of taste, aroma, texture and color. This data uses organoleptic test analysis with 30 respondents. The results obtained are in terms of color, pineapple-flavored popcorn, a score of 125, in terms of taste, pineapple- flavored popcorn, a score of 122, in terms of aroma, pineapple-flavored popcorn, a score of 124, and in terms of texture, pineapple-flavored popcorn, a score of 138. pineapple-flavored popcorn can last at room temperature for 2 days after it has gone through the cooking process. The cost of making popcorn with pineapple flavor is Rp. 16,410 for the manufacture of 1 popcorn box that can hold 100 grams of popcorn
Pengaruh promosi jabatan dan kompensasi terhadap kinerja karyawan di pizza hut sunset road point
Authors: Sentanu I Nyoman Tri Mulya , Mahendra I Wayan Eka , Sulasmini Ni Made Ayu
Published: February 2023

Penelitian ini bertujuan untuk mengetahui pengaruh promosi jabatan, dan kompensasi secara parsial dan simultan terhadap kinerja karyawan di Pizza Hut Cabang Sunset Road Point Bali. Lokasi penelitian ini di Pizza Hut Cabang Sunset Road Point Bali. Sampel yang digunakan dalam penelitian ini sebanyak 40 responden. Teknik analisis data yang digunakan dalam penelitian ini adalah Uji Asumsi Klasik, Analisis Regresi Linier Berganda, Uji Koefisien Determinasi, Uji F dan Uji t. Dari hasil penelitian dapat dilihat bahwa: (1) promosi jabatan berpengaruh positif signifikan terhadap kinerja karyawan, dimana diperoleh nilai t-hitung 3,028 dan signifikansi 0,004. (2) kompensasi berpengaruh positif signifikan terhadap kinerja karyawan, dimana diperoleh nilai t-hitung 3,066 dan signifikansi 0,004. (3) secara simultan promosi jabatan dan kompensasi berpengaruh signfikan terhadap kinerja karyawan, dimana diperoleh nilai F-hitung 20,738 dan signifikansi 0,000. Besarnya pengaruh promosi jabatan dan kompensasi terhadap kinerja karyawan adalah 52,9%. Saran yang dapat diberikan peneliti adalah Pizza Hut Cabang Sunset Road Point Bali diharapkan dalam meningkatkan kinerja karyawan dengan memperhatikan variabel promosi abatan dan kompensasi
 
This study aims to determine the effect of promotion and compensation partially and simultaneously on employee performance at Pizza Hut Sunset Road Point Bali Branch. The location of this research is Pizza Hut Sunset Road Point Bali Branch. The sample used in this study were 40 respondents. The data analysis technique used in this research is the Classical Assumption Test, Multiple Linear Regression Analysis, Coefficient of Determination Test, F Test and t Test. From the research results, it can be seen that: (1) job promotion has a significant positive effect on employee performance, where the t-count value is 3.028 and the significance is 0.004. (2) compensation has a significant positive effect on employee performance, where the t-count value is 3.066 and the significance is 0.004. (3) simultaneously promotion and compensation have a significant effect on employee performance, where the F-count value is 20,738 and the significance is 0,000. The magnitude of the effect of promotion and compensation on employee performance is 52.9%. The suggestion that researchers can give is that Pizza Hut Sunset Road Point Bali Branch is expected to improve employee performance by paying attention to the variables of promotion and compensation
Homogenization of a parabolic equation in a perforated domain with a unilateral dynamic boundary condition: critical case
Authors: Podolskiy A. V. , Shaposhnikova T. A.
Published: February 2023

In this paper, we study the homogenization of a parabolic equation given in a domain perforated by ''tiny'' balls. On the boundary of these perforations, a unilateral dynamic boundary constraints are specified. We address the so-called ''critical'' case that is characterized by a relation between the coefficient in the boundary condition, the period of the structure and the size of the holes. In this case, the homogenized equation contains a nonlocal ''strange'' term. This term is obtained as a solution of the variational problem involving ordinary differential operator.
Pengaruh Penerapan Corporate Social Responsibility PT. Lafarge Cement Indonesia terhadap Kesejahteraan Masyarakat di Kecamatan Lhoknga Kabupaten Aceh Besar
Authors: Jalilah  , Marwiyati  , Akmal
Published: February 2023

Corporate Social Responsibility (CSR) merupakan bentuk tanggung jawab atau kewajiban perusahaan terhadap lingkungan. Setiap perusahaan terutama yang bergerak di bidang Sumber Daya Alam (SDA) memiliki kewajiban untuk menjalankan kegiatan Corporate Social Responsibility (CSR). PT. Lafarge Cement Indonesia (LCI) Lhoknga Aceh Besar merupakan salah satu perusahaan yang juga telah menerapkan CSR dalam beberapa bidang, seperti pendidikan, kesehatan, ekonomi dan agama. Tujuan penelitian ini adalah untuk mengetahui pengaruh pelaksanaan CSR PT Lafarge Cement Indonesia bidang pendidikan, kesehatan, ekonomi dan agama terhadap kesejahteraan masyarakat di Kecamatan Lhoknga. Penelitian ini menggunakan pendekatan kuantitatif melalui penyebaran kuesioner kepada 100 responden yang merupakan masyarakat Kecamatan Lhoknga. Hasil penelitian menunjukkan bahwa pelaksanaan program CSR PT Lafarge Cement Indonesia bidang pendidikan, kesehatan, ekonomi dan agama secara parsial atau simultan berpengaruh signifikan terhadap kesejahteraan masyarakat di Kecamatan Lhoknga Kabupaten Aceh Besar. Berdasarkan hasil uji R square menunjukkan bahwa kesejahteraan masyarakat di Kecamatan Lhoknga Kabupaten dipengaruhi oleh program CSR PT Lafarge Cement Indonesia sebesar 34,5%.
Twitter dan Proses Pencarian Partner ‘Enak-Enak’ (Studi Etnografi terhadap Akun Twitter @FWBESS dan @alterianbase)
Authors: Kamiliya Nayla Andina , Akbar Fauzan Aufa , Afwan Mohammad , Suryo Bagas
Published: February 2023

Perkembangan internet dan media digital telah membawa dinamika baru dalam kajian mikro komunikasi: Komunikasi Interpersonal. Aplikasi berbasis digital dan platform media sosial telah menjadi bagian tak terpisahkan dalam kehidupan dan interaksi masyarakat modern sebagai fasiliyas pemenuhan kebutuhan tertentu. Sekarang ini, media Sosial Twitter pun juga digunakan sebagai wadah bagi kaum muda untuk mencari partner seks kasual melalui akun auto-menfess dengan intensi yang sejalan. Namun, di indonesia sendiri, pencarian partner seks kasual melalui akun auto-menfess membawa masalah yang berkenaan dengan kondisi sosio-kultural, di mana pandangan umum masyarakat tentang moralitas dan agama telah berbenturan dengan pengaruh modern yang dibawa oleh transnasionalisme dan globalisasi budaya. Pada titik ini, teori penetrasi sosial dan keintiman menjadi sangat signifikan dalam menentukan komunikasi interpersonal yang terjadi antar para pencari partner seks kasual melalui akun auto-menfess di Twitter. Oleh karena itu, penelitian ini betrtujuan untuk membedah lebih dalam lagi mengenai hubungan interpersonal yang terbangun di akun auto-menfess tersebut serta bagaimana pemaknaan informan terpilih perihal seks kasual yang mereka dapatkan di sana. Cakupan dari penelitian ini meliputi kajian komunikasi interpersonal khususnya dalam hubungannya antara psikologi media dengan pembentukan budaya digital di kalangan kaum muda urban. Metode data dan penelitian yang digunakan adalah etnografi virtual sebagai metode utama, serta etnografi baru sebagai metode pendukung untuk mendapatkan pengalaman dan pemaknaan pribadi yang mendalam dari para informan. Penelitian ini diharapkan mampu menjawab perihal peranan teori penetrasi sosial dalam pencarian pasangan seks kasual di tengah kondisi sosio-kultural yang ada di Indonesia. Signifikansi dari penelitian ini terletak pada pendekatan media dan isu komunikasi dalam era digital dengan menggunakan perspektif komunikasi interpersonal secar kultural dan kritis, khususnya pada aspek pembangunan suatu hubungan, konsep diri, dan keintiman.
Pengaruh Konten YouTube WOW (Wellspring Of Wellness) Hungary Terhadap Minat Berkunjung Mahasiswa
Authors: Sompie Defanya Daniella Ester , Sondakh Mariam , H. Lotulung Leviane Jackelin
Published: February 2023

This research aims to know The Influence of WOW (Wellspring Of Wellness) Hungary’s YouTube Content Towards Visiting Interest of Students at Communication Science Faculty of Social and Political Science Sam Ratulangi University. The theory used in this research is stimulus-organism-response or s-o-r theory. Research method used in this research is quantitative with data retrieval technique of using questionnaires. The population of this research were 33 Students of Communication Science Faculty of Social and Political Science Sam Ratulangi University who also subscribed to channel Visit Hungary. The result showed that there are 42,1 percent influence between WOW Hungary’s YouTube content towards visiting interest. The most influential out of 5 indicators are Video, Audio and Title, in which many respondes answered with agree and strongly agree, whereas the least influential is Comment. In hypothesis testing, the significant value obtained was 0,000 so Ha was accepted and Ho rejected because the significant value is smaller than 0,05. In conclusion WOW Hungary’s YouTube content has an effect towards the visiting interest of Communication Science students Faculty of Social and Political Science Sam Ratulangi University Manado.
OPINI PUBLIK DI MEDIA SOSIAL TWITTER PADA SOMASI YANG DILAKUKAN OLEH ES TEH INDONESIA
Authors: Alontari Yogie , Karmila Leti , Siddiq Asep Ahmad , Yulianita Neni
Published: February 2023

In the current digital era, social media has become a new public space (public sphere) that is used by the public to communicate and interact, including being used to form a public opinion. On September 24, 2022, PT Esteh Indonesia Makmur, as the company that owns the Indonesian Es Tea brand, made a subpoena to the Twitter account owner who criticized one of its beverage products because it was considered a violation of the ITE Law. This became an issue and generated public opinion on social media Twitter. This study intends to find out and analyze the public opinion that is formed from the community of Twitter users towards subpoenas conducted by Es Teh Indonesia, using a qualitative approach, in the form of the Virtual Communication Ethnographic research method. The results of the study generally stated that a negative public opinion was formed from the public towards the summons made by Indonesian Es Teh. The public considered that what was done was inappropriate and unnecessary, this was reflected in the various insults and ridicule that arose as a result of the subpoena. Although on the other hand there is public opinion which states that the criticism made is considered not good because it uses harsh and impolite language or words.
El escape de la libertad, de Erich Fromm: 80 años de advertencia sobre la amenaza autoritaria
Authors: Orellana Carlos Iván
Published: February 2023

En este ensayo se reflexiona sobre el autoritarismo contemporáneo, a propósito de los 80 años del libro clásico: El miedo de la libertad, de Erich Fromm. Se argumenta que el mensaje principal del texto mantiene su vigencia al advertir sobre los riesgos que se ciernen sobre la democracia ante la llegada de un líder autoritario al cual las masas se someten en busca de resguardo y sentido, en el que el caso salvadoreño sirve para ilustrar la sumisión a líderes populistas en Centroamérica. Mientras la dignidad de las personas no sea colocada en el centro de las preocupaciones políticas, el riesgo de persistir en la idea de escapar de la libertad a través del autoritarismo será siempre una posibilidad latente.