bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of VEGF gene rs699947 and rs2010963 polymorphisms with vascular endothelial growth factor levels in the blood serum of children with lupus nephritis
Authors: Nikitchenko N. N. , Kazyra I. A. , Bialkevich H. G. , Sukalo A. V. , Goncharova R. I.
Published: January 2023

The growth factor genes VEGF and TGFB1 are involved in the normal functioning of the kidneys, and some polymorphic loci of these genes determine a genetic predisposition to the autoimmune diseases, including systemic lupus erythematosus (SLE) and its dangerous complication, lupus nephritis (LN). The products of these genes, in particular, the vascular endothelial growth factor protein and the transforming growth factor β1 protein are used in clinical practice as markers of endothelial dysfunction for early diagnosis of kidney pathology. However, the relationship between the expression of these proteins and the genotypes/alleles of the polymorphic loci of these genes has not been studied enough, which requires clarification of this issue for the child population of Belarus. In this work, we analyzed the associations of the TGFB1 (rs1800469) and VEGF (rs699947 and rs2010963) gene genotypes with the concentration of their products in the blood serum of patients with LN during exacerbation and remission of the disease. The study did not find a significant relationship between polymorphic variants of the TGFB1 gene (rs1800469) and levels of its product in the blood. An association has been established between the rs699947 and rs2010963 polymorphic variants of the VEGF gene and the serum concentration of the gene product in pediatric patients with LN during exacerbation. It was found that the homozygous minor genotype AA of the polymorphic locus rs699947 and the group of genotypes GC + CC containing at least one minor allele of the locus rs2010963 are associated with higher levels of the gene product in the blood serum of children with LN during disease exacerbation (p < 0.001 and p = 0.036, respectively). Thus, VEGF polymorphic variants associated with an increased concentration of the gene product in the blood serum during disease exacerbation can be considered as markers of the risk of disease exacerbation in patients with LN.
Features of manifestation of modern water-erosion processes in the Central Belarus territory
Authors: Kukharik E. A. , Matveyev A. V.
Published: January 2023

The article presents the results of study of the modern water-erosion processes in the Central Belarus territory. The mechanisms of sheet, gully and river erosion are considered. The areas of development of these processes are established and the parameters of annual erosion drift are calculated. The contribution of each process to the dynamics of the earth's surface relief of the region under study is determined. It is shown that the development of water-erosion processes lead to noticeable negative consequences for environment, disruption (up to destruction) of natural and natural-technogenic objects, and significant economic damage.
Heterogeneous radio absorbing composite materials based on powdered charcoals for electronic devices protection from the electromagnetic radiation impact
Authors: Boiprav O. V. , Belousova E. S. , Bordilovskaya D. V.
Published: January 2023

The results of theoretical and experimental substantiation of the technique developed by the authors for the manufacture of heterogeneous (two- or three-layer) radio absorbing composite materials based on powdered charcoals are presented. The technique is based on layer-by-layer pouring of mixtures of a gypsum binder and powdered charcoal (non-activated birch, activated birch, activated coconut) into molds in the order in which the outer (relative to the electromagnetic radiation propagation front) layer of the composite material is characterized by the lowest wave resistance, and the inner layer is characterized by the highest wave resistance. The specified order is determined by the results of the theoretical substantiation of the developed technique. In the course of its experimental substantiation, regularities for changing the electromagnetic radiation reflection and transmission coefficients values of the manufactured materials depending on the value of the radiation frequency in the range of 0.7–17.0 GHz have been established. Based on the established regularities, it was stated that the minimum value of the electromagnetic radiation reflection coefficient of the two-layer materials manufactured according to the developed and substantiated technique (thickness ~ 5.0 mm) is –12.0 ± 1.0 dB and corresponds to electromagnetic radiation frequencies of 0.8 and 2.6 GHz (it’s provided, when such materials are fixed on metal substrates). The minimum value of the electromagnetic radiation reflection coefficient of the three-layer materials (thickness ~ 10.0 mm) under the specified condition is also –12.0 ± 1.0 dB and corresponds to electromagnetic radiation frequencies of 4.5 and 6.0 GHz. The electromagnetic radiation transmission coefficient values of such materials decrease with an average step of 4.0 dB as the frequency of the radiation increases by 1.0 GHz in the range of 2.0–10.0 GHz and increase with a similar step as the frequency increases by 1.0 GHz in the range of 10.0–17.0 GHz. The minimum value is –30.0 ± 2.0 dB. The materials manufactured according to the developed and substantiated technique seem to be promising for ensuring the protection of electronic devices from the effects of electromagnetic interference (both active and passive types).
Influence of ionizing radiation on the parameters of p-channel MOS transistors
Authors: Bogatyrev Yu. V. , Aharodnikau D. A. , Lastovsky S. B. , Ket’ko A. V. , Krechko M. M. , Shpakovsky S. V. , Rubanov P. V. , Protopopov G. A. , Chubunov P. A.
Published: January 2023

The results of experimental studies of the influence of gamma radiation Co60 on the basic parameters of silicon epitaxial-planar p-channel MOSFET transistors under different electrical modes are presented. Transistors were manufactured according to radiation-resistant DMOS technology with design standards of 1.4 μm. As a result of transistor studies, it was established that the values of all basic parameters after the radiation dose D = 106 rads (SiO2) in active electrical irradiation modes remained within the limits of the performance criteria; the parameter, most sensitive to influence of a dose of irradiation by gamma-quanta is the threshold voltage; in the passive electrical irradiation mode the transistor’s radiations resistance in all parameters corresponds to a dose of 2,8·106 rads (SiO2). A sufficiently high radiation resistance of the studied p-channel MOSFETs makes it possible to recommend them for use in aviation and space equipment. The different degrees of radiation degradation of the studied parameters during irradiation are due to their dependence either on the effects of ionization in the layers of sub-gate and insulating dielectrics, or structural damage in the bulk silicon of the transistor active regions. The high radiation resistance of the studied p-channel MOSFETs allows recommending them for use in aviation and space equipment.
Factors of sustainability of the agricultural sector of Belarus to the manifestation of risks
Authors: Pavlovich L. M.
Published: January 2023

Considers the role of risk management in ensuring the sustainable functioning of the agroindustrial complex in modern conditions is considered. The key risks in the agricultural sector of the Republic of Belarus for 2012–2021 are identified, their features and the results of the offensive are described. A review of the effectiveness of the response of the state agrarian policy to the identified situations was carried out, recommendations were given for its improvement. It has been determined that an important feature of the domestic risk management system in agriculture is its continuous transformation in the direction of increasing the speed and efficiency of taking anti-risk measures, using economically sound tools and minimization methods, and introducing modern methods for predicting challenges, dangers and threats.
Information interaction in the field of quality of food raw materials and goods in the Republic of Belarus
Authors: Rastorgouev P. V. , Pochtovaya I. G.
Published: January 2023

The analysis of the information interaction system in the field of quality of agrifood products in Belarus is presented. The features of functioning and development trends of the mechanism information interaction of subjects in the designated area are highlighted.
Management of marketing complex elements in the beet sugar subcomplex of the Republic of Belarus
Authors: Kokits E. V.
Published: January 2023

Discusses the peculiarities of the environment of functioning and management of elements of the marketing complex in the beet sugar subcomplex in Belarus. The dynamics of exports and imports in the context of countries for 2017–2021. The structure of exports and imports shows a high share of the Russian Federation (55 and 65,2 %, respectively). Currently, enterprises operate in a complex, volatile, highly uncertain marketing environment, so marketing activities are of particular importance to such enterprises. Marketing management is a complex organizational activity and includes the analysis, planning, execution of activities and control over the implementation of activities aimed at establishing, strengthening and maintaining profitable exchanges with target buyers in order to achieve the necessary levels of sales, profit and market share.
Prediction of the infrainguinal revascularizing surgery outcomes in patients with diseases of the lower limb arteries
Authors: Panasyuk O. , Mogilevets E. , Kopytsky A.
Published: January 2023

The progressive course of lower extremity arterial disease (LEAD) inevitably leads to the development of intermittent claudication, critical ischemia, and gangrene. If a patient shows signs of critical ischemia and trophic disorders, he should undergo revascularization surgery. The development of reocclusion may be observed in the early period following the surgery. The aim of the work was to develop and validate a prognostic model of the results of revascularizing surgeries below the inguinal ligament. The study involved 133 patients with chronic arterial insufficiency of stages II B, III and IV according to Fontaine-Pokrovsky classification. 92 patients underwent open surgeries and 41 underwent endovascular surgeries. To build a prognostic model, 244 criteria were analyzed. The final model was built on the basis of such criteria as surgery type, levels of total cholesterol, homocysteine, cysteinylglycine, ankle brachial index increase, and diameter of the common femoral artery. This prognostic model has the following characteristics: Se = 85.71%, Sp = 82.56%, Acc = 83.33%
Knowledge Level of Midwives before and after an Online Training Participation
Authors: Nurdiawan Windi , Irianti Setyorini , Puspita Dyah Ayu , Zeus Alfonsus , Anggara Billy Nusa , Sinaga Vebri Anita , Iswari Wulan Ardhana , Hans Will , Prasangka Eduward Yacub , Zulfa Fadhilah
Published: January 2023

Fetal growth restriction is a prevalent pregnancy issue linked to numerous unfavorable postnatal outcomes. Suboptimal uterine-placental perfusion and inadequate fetal feeding are the vital pathophysiologic causes. Midwives play a crucial role in informing pregnant women about vitamin D inadequacy. This paper aims to determine the difference between midwives' prior and post-webinar knowledge levels. It was a cross-sectional study of individuals who participated in a webinar on November 21, 2021. Subjects were selected using a total population sampling approach from all midwives who participated in the webinar and completed pre-and post-tests. The difference between knowledge levels was evaluated using the difference between the pre-test and post-test scores in the general category. There was an increase in the number of participants who successfully answered the five-question component, a decrease in the number of participants who correctly answered the two-question section, and no change in the number of subjects who correctly answered question number one. The average score on the post-test was higher (67.28) than the pre-test (63.10), while the median score was the same at both time points. After attending a webinar, there was an increase in the proportion of subjects with a high level of knowledge (11.4% to 24%) and a drop in the proportion of subjects with a poor level of knowledge (32.3% to 27.1%). In conclusion, there was an improvement in the knowledge level of midwives before and after the webinar participation.
METHODOLOGY FOR AVOCADO (Persea americana Mill.) ORCHARD EVALUATION USING DIFFERENT MEASUREMENT TECHNOLOGIES
Authors: Chumbimune Sheyla Y. , Cardenas Gloria P. , Saravia David , Valqui Lamberto , Salazar Wilian , Arbizu Carlos I.
Published: January 2023

Avocado crop (Persea americana Mill.) is of great commercial importance due to its high profitability. However, it is being affected by various diseases and pests that affect yield and reduce fruit quality. The aim of this research was to develop methodologies for the evaluation of avocado plantations using different non-destructive technologies for rapid phenotyping and early detection of the incidence of diseases or damage due to stress in the stem. A plot of 0.7 ha. was evaluated, with a total of 44 individuals using Field-Map technology (dasometric and morphological characterization), RGB-multispectral images from Remotely Piloted Aircraft System (RPAS) (rapid phenotyping), while 15 individuals were evaluated using tomography (assessment of the internal state of the stem). The results with tomography indicated that there is a tree with wood rot of 14% with a lower acoustic speed with respect to the other trees evaluated. A high correlation was observed between the dasometric variables (r-Pearson from 0.63 to 0.98) estimated with Field-Map [crown base height, crown projection (m2 ) and total height] and with RPAS (height, perimeter and area). The vegetation indices do not have a direct correlation with the dasometric variables; five of the indices have a high contribution to variability except for the Normalized Difference Red Edge (NDRE). It can be concluded that the technologies used in this study would help to perform evaluations with a greater number of reliable and precise data with respect to the information obtained in a traditional way, while they can be replicated in commercial plots or research studies of different perennial crops, generating useful information for management decisions and crop evaluation.
EFFECT OF THE COMBINED APPLICATION OF MANURE COMPOST AND Trichoderma sp. ON PRODUCTION PARAMETERS AND STEM ROT DISEASE INCIDENCE OF SHALLOT
Authors: Lasmini Sri Anjar , Edy Nur , Yunus Mohammad , Haji Nasir Burhanuddin , Khasanah Nur
Published: January 2023

Manure compost is a type of organic fertilizer derived from animal feces. Even though compost has a slow-release nature, it can be a good alternative to chemical fertilizers. The addition of Trichoderma sp. as a decomposer microorganism can accelerate nutrient availability. The objective of this study was to determine the effect of the combined application of different types of manure compost and doses of Trichoderma sp. on the growth performance, yield as well as stem rot disease incidence of shallot (Allium cepa L. var. aggregatum). The study was carried out using a split-plot design (P 0.05) with the types of manure compost as the main plot with five levels (no compost, cattle manure, chicken manure, goat manure, and petrogenic compost), and different doses of Trichoderma as subplots with three levels (no Trichoderma, 200 kg ha-1, and 400 kg ha-1). In general, the combined application of manure compost and Trichoderma significantly increased growth performance and yield of shallot compared to no compost (B0) and Trichoderma (T0). However, no differences were observed between manure compost and the addition of Trichoderma. Growth performance of shallots grown in soil amended with cattle manure compost was better compared to the other treatments. The use of 5 t ha-1 cattle manure compost combined with 400 kg ha-1 Trichoderma increased yield by 10.02 t ha-1 and reduced stem rot diseases incidence by 0.67%.
DETERMINACIÓN EXPERIMENTAL DE PARÁMETROS AERODINÁMICOS DE SETOS DE BUGAMBILIA (Bougainvillea spectabilis) COMO CORTINAS ROMPEVIENTOS
Authors: Laffita Leyva Alexander , Martínez Rodríguez Arturo , Valdés Hernández Pedro A. , Ávila González Enmanuel , Rodríguez Grimón René O.
Published: January 2023

El objetivo de este trabajo fue determinar experimentalmente los parámetros aerodinámicos de setos de Bugambilia a emplear como cortina rompevientos para su caracterización como medios porosos en los programas comerciales de dinámica de fluido computacional. Esta investigación pertenece a un proyecto aprobado por el Programa Nacional de Energía de Cuba. Muestras de setos de Bugambilia con densidad aparente del follaje de 7,19 kg m-3 fueron sometidas a la acción de corrientes de aire en un túnel aerodinámico construido en el Centro de Mecanización Agropecuaria (CEMA) de la Universidad Agraria de La Habana. El diseño experimental contempló tres niveles de profundidad de la cortina (1; 1,5 y 2 m) y cuatro niveles del flujo volumétrico del aire (entre 5,2 y 7,5 m3 s-1). Se encontraron diferencias estadísticamente significativas entre los tres niveles de profundidad en términos de porosidad aerodinámica de la cortina ( ), con valores promedio de 0,77 0,05; 0,70 0,07 y 0,64 0,08; resistencia al paso del fluido por la cortina ( ), con valores promedio de 6,39; 9,96 y 12,69 s-1; y coeficiente de arrastre, con valores de 0,35; 0,55 y 0,89 para 1; 1,5 y 2 m de profundidad, respectivamente. Se obtuvo modelos estadísticos lineales para la predicción de la diferencia de presión ( en función del flujo volumétrico, con coeficientes de determinación de 0,68; 0,77 y 0,78 para los tres niveles de profundidad de la cortina estudiados.
GENETIC STRUCTURE AND DIVERSITY OF A PERUVIAN COLLECTION OF A HIGH-QUALITY WOOD TREE SPECIES, ULCUMANO (Retrophyllum rospigliosii, PODOCARPACEAE)
Authors: Saldaña Carla L. , Cancan Johan D. , Salazar Evelyn J. , Chumbimune Sheyla Y. , Jhoncon Jorge H. , Arbizu Carlos I.
Published: January 2023

Ulcumano, which is native to South America, is an important conifer in Peru. Molecular studies are scarce, limiting modern breeding and appropriate conservation activities. Currently, molecular markers are widely employed to explore genetic structure and diversity parameters of plant species in a fast and precise manner. The objective of this study was to analyze the genetic diversity and population structure of ulcumano in Peru by using DNA-based molecular markers. Nine Randomly Amplified Polymorphic DNA (RAPD) markers were used, while 95 individuals of ulcumano were sampled from three departments of Peru. A total of 265 DNA fragments were manually scored, but 247 of them were kept after removing the non-polymorphic markers. Genetic distances were calculated using R software based on Provesti´s coefficient. A dendrogram was obtained using the UPGMA clustering algorithm, showing no clear clustering. The principal coordinate analysis agreed with two population structure analyses, demonstrating that ulcumano is contained within two clusters, (i) Junín + Pasco, and (ii) Cajamarca, while very few individuals are intermixed. Genetic diversity parameters were estimated considering the two groups (populations) identified by STRUCTURE software. Nei's genetic diversity estimate varied between 0.22 and 0.28, while Shannon index ranged from 3.43 to 4.16. Population divergence (Fst) between the two clusters revealed low genetic differentiation (0.064). AMOVA analysis revealed that 87.31 and 12.69% of the total genetic variation were found within populations and between individuals, respectively. To the best of our knowledge, this is the first molecular study in ulcumano in Peru, and provides valuable information for the genetic improvement and sustainable management of this conifer in the country.
El olvido termina cuando se hace memoria. Orlando Rodríguez Benito, docente y crítico del teatro universitario chileno. 1953-1973
Authors: Wallffiguer Belmar Daniela
Published: January 2023

El artículo reconstruye la trayectoria de Orlando Rodríguez, docente y crítico teatral chileno, entre 1953 a 1973, en dónde su contribución cultural estaba en el olvido. La metodología utilizada es un ejercicio entre historia y memoria. Por esa razón, revisamos prensa sobre teatro y lo complementamos con testimonios orales de sus exestudiantes, hoy artistas chilenos de la escena. Por consiguiente, historia y memoria, permiten identificar el rol del teatro chileno hasta el Golpe de Estado. Finalmente, Rodríguez fue un reflejo cultural del ambiente, ya que, el teatro se hizo parte de las movilizaciones sociales, posibilitando el ascenso de la Unidad Popular.
Consideraciones anestésicas del Síndrome de Anderman. A propósito de un caso.
Authors: Elena Rodríguez Porras  , Elena Serón Ardananz  , Rosana Guerrero Domínguez
Published: January 2023

El síndrome de Anderman es una neuropatía sensitivo-motora desmielinizante progresiva hereditaria, de carácter autosómico recesivo, debida a una mutación del gen SLC12A6, encargada de la síntesis del cotransportador K-Cl que parece ser necesaria para el desarrollo y sustento del tejido nervioso. Estos pacientes presentan un fenotipo de facies dismórfica con hipertelorismo y braquicefalia, arreflexia generalizada, amiotrofia y contracturas musculares severas. Las comorbilidades asociadas y las peculiaridades anatómico-funcionales pueden condicionar el manejo perioperatorio suponiendo un reto para el anestesiólogo. A propósito de un caso realizaremos una revisión de este síndrome remarcando los puntos que consideramos importantes con el objetivo de que sirvan a otros anestesistas como referencia a la hora de enfrentarse a estos pacientes.
Myth of Leviathan (On Giorgio Agamben’s Reading of the Dispute between Walter Benjamin and Carl Schmitt)
Authors: Belkovich R.Yu. , Khabibulin T.M.
Published: January 2023

The article is devoted to one of the key disputes for the intellectual history of Europe in the last century, which unfolded in the first half of the 20th century between Walter Benjamin and Carl Schmitt. The starting point of the analysis is the reading of this dispute by Giorgio Agamben. According to Agamben, the main point of disagreement between the two thinkers is the possibility of the existence of violence, completely autonomous from law and sovereign power. Answering this question in the affirmative, Benjamin introduces the category of pure violence, which, from his point of view, is capable of destroying the existing law without recreating the logic of power institutions. Schmitt opposes this argument, appealing to his theory of the state of emergency, in which there is no violence outside the realm of law. In the course of the study, the authors take into account another thinker — Georges Sorel, whose views influenced both participants in the dispute. The authors focus on Sorel’s concept of political myth and utilize it to discuss another important point of tension between Benjamin, Schmitt, and Agamben (to the extent that he spoke about the matter of the dispute) — Thomas Hobbes’ treatise Leviathan. After analyzing the conflict of interpretations of the eschatological myth ascribed to the treatise, the authors come to the conclusion that de facto at the core of the controversy between Benjamin and Schmitt lies the possibility of overcoming the political myth, which underlies modern political institutions, and the main strategy of the participants of the dispute is the localization of this myth.
Pengenalan Dialek Bahasa Daerah di Pulau Jawa menggunakan Metode Mel-Frequency Cepstral Coefficients dan Adaptive Network-based Fuzzy Inference System
Authors: Fauzi Fajar Muhammad , Hayat Latiful , Kusuma Hardani Dian Nova
Published: January 2023

Indonesia merupakan negara besar yang memiliki banyak keberagaman budaya dan suku sehingga memiliki banyak bahasa atau dialek yang berbeda-beda di setiap daerah. Berbagai penelitian dalam pengolahan sinyal suara telah banyak dikembangkan. Salah satu penelitian yang menarik untuk dikembangkan adalah Identifikasi Dialek. Dalam penelitian ini, dibuat suatu program atau aplikasi Speech Recognition dengan metode Mel-Frequency Ceptrums Coefficients (MFCC) dan Adaptive Neuro Fuzzy Inference System (ANFIS) untuk Bahasa Jawa dialek Betawi, Sunda, Banyumasan, dan Suroboyoan. MFCC untuk proses ekstraksi ciri dari sinyal ucapan pembicara dimana prosesnya akan mengubah sinyal suara menjadi beberapa vektor ciri yang kemudian akan ditampilkan dalam bentuk grafik. Analisis dan perancangan bentuk pola suara menggunakan software Phyton. Pengujian dilakukan dengan cara merancang perangkat lunak, melakukan pengambilan data, training sistem ANFIS, pembuatan GUI, dan pengujian dalam pengolahan data pengujian. Hasil dari penelitian ini menunjukkan MFCC mampu memberikan nilai ciri yang berbeda untuk setiap suara yang dimasukkan ke dalam sistem, dan parameter MFCC yang digunakan pada penelitian ini adalah Preemph = 0,99, Nfilt = 30, Nfft = 512, Winlen = 20ms, Winstep = 10ms, Numcep = 5, dan Lowfreq = 100. Model training yang digunakan dengan 120 data training dan 2 membership function tipe gausian menghasilkan nilai akurasi secara keseluruhan 32,5% pada proses pengujian ( 30% untuk Betawi, 50% untuk Sunda, 30% untuk Banyumasan, dan 20% untuk Suroboyoan).
Implementasi Jaringan Hotspot Dengan Sistem Koin Menggunakan Raspberry Pi Dirumah Makan UMI
Authors: Riyan Richi , Pramono Sigit , Romadhona Shinta
Published: January 2023

Perkembangan teknologi khususnya internet sangat berperan dalam kehidupan sehari-hari. Di era modern ini kebutuhan akan internet sudah menjadi hal utama bagi Sebagian besar orang. Rumah makan merupakan usaha mikro yang sangat menguntungkan. Hal ini berdampak pada usaha rumah makan untuk lebih berpikir kreatif dalam menciptakan konsep yang berbeda dari rumah makan yang lainnya. Peningkatan fasilitas pemilik rumah makan dilakukan dalam hal penyedian akses internet secara gratis seperti hotspot agar menarik para konsumen untuk makan dan bersantai menghabiskan waktu luang. Dengan memanfaatkan Mini PC sebagai pengontrol jarak jauh melalui bahahsa pemrograman,menjadikan lebih efisien. Pada penelitian ini menggunakan mini PC Raspberry Pi 3 model b yang memiliki fitur GPIO (general Purpose  input output) yang berfungsi sebagai port-port yang mengirimkan perintah sesuai instruksi atau sesuai dengan program yang dibuat. Dalam penelitian ini menggunakan percobaan uang koin 1000 dan 500. mencari jumlah waktu dan bandwidth yang akan didapatkan oleh user. Pada percobaan ini Dilihat dari waktu dan bandwidth yang didapatkan bahwa uang koin 1000 memiliki waktu 10 menit perkoinnya sedangkan uang koin 500 memiliki waktu 5 menit perkoinnya, pada perbandingan ini memiliki besar bandwidth yang sama yaitu 1.024mbps. Waktu dan jumlah bandwidth hanya dapat disetting oleh admin sebagai user hanya mendapatkan apa yang sudah di setting oleh admin.
Monocyte-to-HDL Cholesterol Ratio As A New Parameter of Systemic Inflammation and Disease Severity in Treatment-Resistant Chronic Spontaneous Urticaria
Authors: KAYA Özge , IŞIK MERMUTLU Selda
Published: January 2023

Background and Purpose: Chronic spontaneous urticaria (CSU) is characterized by inflammation and increased oxidative stress in its pathogenesis. The study aims to evaluate new inflammatory markers indicating systemic inflammation in resistant CSU and to determine their relationship with disease severity.

Methods: The files of CSU patients and matched healthy volunteers were reviewed and compared in terms of demographics, medical history, clinical features, laboratory parameters, and new inflammatory markers [NLR:neutrophil-lymphocyte ratio, MLR: monocyte-lymphocyte ratio, MHR:monocyte-to-high-density lipoprotein cholesterol (HDL-C)].

Results: Sixty-one CSU patients and 50 healthy controls were evaluated (female: male ratio=1.9:1, mean age=43.97 ± 14.88 years). The median erythrocyte sedimentation rate, C-reactive protein (CRP), white blood cell, monocyte count, and MHR were higher in the CSU group; in contrast, the mean HDL-C level was lower. The median NLR and MLR were also higher in the CSU group but were not statistically significant. Urticaria activity score 7 (UAS7) was positively correlated with MHR and negatively correlated with HDL-C. MHR was positively correlated with MLR, CRP, and UAS7.

Conclusions: MHR might serve as an indicator of inflammation intensity and predisposition to MS in CSU patients. It might also be used as an objective tool for evaluating disease severity and treatment response in CSU.
Penguatan Budaya Literasi di Pondok Pesantren El Karim Cibuah Warunggunung Lebak Banten Melalui Gerakan Literasi
Authors: Ferieka Hendrieta , Syahid Ahmad Habibi , Alhaq Falikh
Published: January 2023

Banten as a province, is also known as an area with the nickname " Seribu Kyai Sejuta Santri". The nickname is inseparable from the reality of the existence of Islamic boarding schools that are growing in large numbers in the province of Banten. Starting from traditional boarding schools to modern boarding schools. Pesantren is an institution that provides religious education services. On the Pondok Pesantren Database page released by the Directorate of Islamic Boarding School Education (DITPDPONTREN), the Ministry of Religion, R.I. it is stated that the total number of pesantren in Banten province is 4,579 pesantren. Pesantren not only teach religious education but also life education so that students are able to become independent individuals when they leave the pesantren. As mentioned earlier, the existence of many Islamic boarding schools and the activeness of these institutions in providing religious education services has a linear line with the religious pattern of the people who are known to be religious fanatics. Even so, this linear line does not apply to literacy and writing cultures. Therefore, community service activities through strengthening literacy culture among students need to be carried out. Modern Islamic Boarding School El Karim Cibuah Warunggunung Lebak Banten was chosen as the location of the activity by looking at the availability of programs to be implemented which are in line with the program to strengthen literacy culture in Islamic boarding schools.
An Increasing Reading Interest and Literacy Development Through the Creation of Pioneer Libraries for PAUD Students
Authors: Dewi Santi Riana , Santi Octaviani  , Andari  , Martina Rahmawati Masitoh
Published: January 2023

At this time the existence of a pioneer library is an important thing that must be improved in quality and quantity for the purposes of scientific development. Especially during the pandemic, school children tend to prefer playing games using gadgets or cellphones rather than reading books. Therefore, it is necessary to increase reading interest and literacy development for school students, including PAUD students. The lack of availability of books and other supports is the main reason for the lack of interest in reading and the development of literacy. Community service begins with conducting interviews with PAUD leaders and identifying the situation in PAUD, then continuing with providing motivation, assistance in improving literacy and donating reading books and other supports in order to form a pioneer library for students. The creation of a library is intended for students with the guidance of teachers and parents of students. Currently there are 4 teachers and 25 students. Before the service at PAUD there was no library with adequate books and supports. After the implementation of the program, teachers and students became increasingly enthusiastic about increasing book reading activities and improving overall literacy. In the future, it is hoped that the library will continue to grow through the cooperation of universities, government and local government officials.
DOMPET DIGITAL SEBAGAI ALAT ALTERNATIF PEMBAYARAN NON-TUNAI PADA UMKM DI DESA PADANGSAMBIAN
Authors: Trihanura Pranurti Claudya , Basmantra Ida Nyoman
Published: January 2023

Pandemi Covid-19 yang dihadapi Indonesia khususnya di Bali saat ini, memaksa usaha mikro kecil dan menengah yang sebelumnya tidak menggunakan platform digital sebagai alternatif alat untuk pembayaran kini harus menerapkan dalam usaha mereka. Minimnya pengetahuan para pelaku UMKM di desa Padangsambian Bali saat ini akan manfaat dari platform pembayaran digital tentu akan berakibat pada menurunnya tingkat ketertarikan konsumen untuk melakukan transaksi terhadap produk yang ditawarkan. Melihat permasalahan yang terjadi, maka akan dilakukan sosialisasi edukasi mengenai manfaat dari platform pembayaran digital melalui pemanfaatan e-wallet bagi UMKM. Tujuan dari program sosialisasi edukasi untuk meningkatkan pengetahuan pemilik UMKM agar dapat memanfaatkan platform e-wallet sebagai alternatif alat pembayaran digital ditengah pandemi sehingga dapat meningkatkan efektifitas serta daya tarik konsumen untuk melakukan transaksi. Metode yang digunakan adalah dengan menerapkan strategi komunikasi kepada pemilik usaha mikro kecil dan menengah (UMKM). Hasil dari sosialisasi ini akan membantu UMKM di desa Padangsambian untuk meningkatkan penjualan dan menjadi lebih kompetitif di era digital.
Optimalisasi Kader Pemberdayaan Manusia Untuk Pencegahan Stunting
Authors: Harianti Rini , Mianna Rika , Hasrianto Nofri , Wiji Rizki Natia
Published: January 2023

Angka prevalensi stunting di Kabupaten Kampar mengalami penurunan dari tahun 2017 sebesar 23% dari jumlah balita di Kampar hingga tahun 2019, mampu diturunkan menjadi 11,88% yang melebihi target nasional sebesar 14%, namun tren penurunan tersebut harus tetap dipantau. Desa Rimbo Panjang memiliki kader pemberdayaan manusia (KPM) yang sudah terbentuk kurang lebih 1 tahun dan merupakan bagian dari kader desa yang memiliki tugas khusus terkait program konvergensi pencegahan stunting. Pola kerja KPM belum dilaksanakan secara optimal terutama dalam hal target dan monitoring pelayanan kesehatan dan gizi. Kegiatan pengabdian masyarakat ini bertujuan untuk mengoptimalkan peran KPM dalam pencegahan stunting di Desa Rimbo Panjang. Kegiatan dilaksanakan pada bulan April-Mei 2021 yang diikuti oleh 14 orang kader. Kegiatan ini dibagi menjadi beberapa tahap, yaitu (1) persiapan, (2) pelaksanaan, dan (3) evaluasi. Metode pelaksanaannya dilakukan melalui penyuluhan, pelatihan atau praktik, dan simulasi. Hasil kegiatan PKM ini adalah terjadinya transfer ilmu pengetahuan melalui berbagai metode yang disajikan. Diharapkan kedepannya dengan meningkatkan pengetahuan dan keterampilan kader dapat diimplementasikan dalam kegiatan posyandu balita sehingga dapat berpartisipasi dalam pencegahan stunting. Kegiatan ini dapat dilanjutkan mengenai pelatihan aplikasi e-ppgbm yang merupakan pencatatan dan pelaporan gizi masyarakat berbasis elektronik.
Training On Working Programs For Pokdarwis Golo Cucu In Kempo Village, West Manggarai Regency
Authors: Rudiyanto Roseven , Lidia Trivonia Delfina , Jun Venansius Kafaso , Ranu Fransiskus Safdianto , Ajeng Maria Patricia
Published: January 2023

Pokdarwis is a form of direct community involvement in tourism development in their environment. Kempo Village is one of the tourist villages in West Manggarai Regency. In this village there is a Pokdarwis Golo Cucu. The problem faced by Pokdarwis Golo Cucu in an effort to develop tourist villages is that there is no work program. This makes the performance of Pokdarwis not optimal. The purpose of this Community Service activity is to train Pokdarwis Golo Cucu members in preparing work programs, so that tourism development in Kempo Village has a focus and measurable results. The method of implementing this PKM activity is Focus Group Discussion by conducting pre-test and post-test. The final result of this activity is the drafting of a work program and a business plan for Pokdarwis Golo Cucu to develop tourism in Kempo Village. In addition, there was an increase in the knowledge of Pokdarwis members seen from the results of the pre-test and post-test. The sustainability plan of this activity is further training to improve promotion and manufacture of ready-to-sell tourism products.
Improving Digital Literacy Skills for Youth Karang Taruna, Cigadung Village, Cibeunying Kaler District, Bandung City
Authors: Mariane Ine , Sariningsih Yuce , Buanawaty Riksa Alam , Azis Hari Abdul
Published: January 2023

Based on the results of the situation analysis, there are several problems with Youth Karang Taruna, Cigadung Village, Cibeunying Kaler District, Bandung City, namely: Low knowledge and understanding of digital literacy and low Digital Literacy Ability to become Smart Vlogers in order to become a productive generation. The purpose of this community service activity is to increase knowledge, understanding and ability about the Importance of Digital Literacy through Creativity Development to become a Smart Vloger as well as strengthening community social institutions in preventing online violence and cyber crime in people's lives, creating independence and a productive generation. The methods used are socialization and counseling, training, mentoring, and technical guidance. As a result of PKM activities, it is hoped that the Youth Karang Taruna, Cigadung Village, Cibeunying Kaler District, Bandung City will know, understand digital literacy, and be able to use internet digital media literacy skills safely in updating writing on the platforms they created to become Smart Vlogers to strengthen institutions. society in preventing online violence and cyber crime in people's lives, creating independence and a productive generation.
Pengaruh Sales Promotion, Hedonic Browsing, dan Impulse Buying Tendency terhadap Impulse Buying Pelanggan E-Commerce Shopee
Authors: Masitoh Martina Rahmawati , Prihatma Gugup Tugi , Alfianto Alfin
Published: January 2023

Abstrak: Penelitian ini bertujuan untuk menyelidiki pengaruh sales promotion, hedonic browsing, dan impulse buying tendency terhadap impulse buying pada pelanggan E-Commerce Shopee di Indonesia. Penelitian ini merupakan penelitian kuantitatif dan merupakan penelitian survei. Metode pengambilan sampel dengan menggunakan purposive sampling. Data didapatkan dari penyebaran kuesioner. Sampel dalam penelitian ini adalah 111 responden. Data diolah secara statistik dengan menggunakan Structural Equation Modeling (PLS-SEM). Pengujian instrument penelitian dilakukan dengan pengujian validitas konvergen dan validitas diskriminan. Penelitian ini juga menghitung koefisien determinasi. Pengujian hipotesis dengan melihat nilai koefisien jalur. Hasil penelitian menunjukkan bahwa sales promotion, hedonic browsing, impulse buying tendency berpengaruh secara positif dan signifikan terhadap impulse buying.

 

Kata kunci: sales promotion, hedonic browsing, impulse buying tendency, dan impulse buying
The Re-Narrate the Relevance of Justice in Debtor Protection Related to the Parate Execution Carried Out by Separatist Creditors
Authors: Riyanto Taufan Fajar , Taufiq Muhammad
Published: January 2023

The existence of Articles 55 and 56 of Act No. 37 of 2004 concerning Bankruptcy and Suspension of Debt Payment Obligations, the position of debtor protection in the implementation of bankruptcy carried out by separatist creditors against creditors is weak. This is due to the absence of legal remedies that can be taken by debtors during bankruptcy has been found to have happened to him. Therefore, it is necessary to have a disposition of justice in protecting debtors from the rights of separatist creditors. The implementation of bankruptcy as referred to in Article 55 and Article 56 of Act No. 37 of 2004 has not been fair to the debtor, considering that the two articles are only based on the existence of debt from the debtor and are related to the position of solvent or insolvency based on the creditor's view. This is clearly the case because Act No. 37 of 2004 does not adhere to a balance sheet test system where before being declared bankrupt, it is necessary to test the condition of the debtor whether it is really insolvent or actually still solvent. 2) The factors that have resulted in bankruptcy law so far have not been fair to debtors are legal factors, namely in the form of the provisions of Article 55 and Article 56 of Act No. 37 of 2004 which are unfair to debtors. The law even though is widely known that the door to justice in bankruptcy cases is the judge's decision. 3) It is necessary to reconstruct Article 55 and Article 56 of Act No. 37 of 2004. So that the provisions of Article 55 and Article 56 of Act No. 37 of 2004 read: Article 55 of Act No. 37 of 2004: 1) Due to observance of the provisions as referred to in Article 56, Article 57, and Article 58, each Creditor holding a lien, fiduciary guarantee, mortgage, mortgage, or other collateral right, may exercise his rights as if there had been no bankruptcy.
Analysis of the Relationship between Green Bonds and Equity Markets by Cross-Quantilogram Method
Authors: BÜYÜKOĞLU Burak
Published: January 2023

In our rapidly growing and developing world, various environmental and climate problems are experienced due to this development. Many countries are turning to renewable energy investments to meet their energy needs with the increasing population and industrialization. This raises the question of how to finance renewable energy investments. To overcome these problems, many environmentally friendly projects and investments have come to the fore and have been financed in recent years. Undoubtedly, one of the most important factors in providing this financing is green bonds. Green bonds have become an important financial instrument for financing environmentally and climate-beneficial projects and renewable energy investments. In the study, it is aimed to analyze the relationship among the daily data between 31.07.2012 and 29.07.2022 and the S&P 500 and S&P Green Bond Index by using the Cross-Quantilogram method. The cross-quantilogram method is an innovative method that can be easily used to determine the cross-correlation relations between different quantile and delay values and variables. According to the empirical results obtained in the study, there is a negative correlation between 2014 and 2018 according to the bidirectional cross-correlation data between the S&P 500 index and the S&P Green Bond index.
İlk Halka Arzların BİST100 Endeksi Volatilitesine Etkisi: Covid-19 Pandemisi Dönemi
Authors: BAYRAKTAR YETİM Seçil , KOY Ayben
Published: January 2023

Covid-19 pandemisinin borsalar üzerindeki etkisi 2020 yılının ilk çeyreğinde büyük bir çöküş ve hızlı bir toparlanma süreci olarak gerçekleşirken, kapanma önlemleri ile birlikte finans piyasalara büyük bir ilgi ve yatırımcı sayılarında artışa sebep olmuştur. Özellikle aşının bulunmasından sonra finans piyasalarındaki olumlu seyir çok sayıda halka arzı da beraberinde getirmiştir Bu çalışmanın amacı Covid-19 dönemi öncesi ve Covid-19 döneminde ilk halka arzların BİST 100 Endeksinin (BİST100) volatilitesine etkisini araştırmaktır. Çalışmaya Covid-19 dönemi öncesi (2018-2019) ve Covid-19 dönemi (2020-2021) 36 ilk halka arz dahil edilmiştir. Çalışmada, 01/01/2018-31/12/2019 tarihleri arası Covid-19 dönemi öncesi seçilmiş olup, Covid-19 dönemi için ise 01/01/2020-28/09/2021 tarihleri incelenmiştir. GARCH modellerinin uygulandığı çalışmanın sonucunda, Covid-19 dönemi öncesinde ilk halka arzların BİST100 volatilitesine sadece halka arz olduğu ilk gün incelendiğinde anlamlı bir sonuç bulunamazken; Covid-19 döneminde volatiliteyi azalttığı sonuçlarına ulaşılmıştır. Bulgular, halka arzın ilk 10 gününde Covid-19 pandemi dönemi öncesinde volatilitede azalışa yol açarken, Covid-19 pandemi döneminde ise volatiliteyi arttırdığını göstermektedir.
SHEIKH SALMAN DAIM AND THE TAREKAT OF NAQSYABANDIYAH AL-KHOLIDIYAH JALALIYAH
Authors: Perangin-angin Mawaddah
Published: January 2023

Abstract: The tarekat is seen as something traditional, which appears to set itself off from modern life. In reality, though, life can not ignore modernism. Consequently, there must be a connection between the roles of Sufism and modernity. The acceptance of this modernism may be seen in the ideas and principles that Sheikh Salman Da'im teaches his students. This research is qualitative and use a character research approach to analyze the thoughts and influences of a character. Data collected from library materials such as books, newspapers, articles and in-depth interviews by using open questions. The problem formulation of this research is the leadership ideals taught by Sheikh Salman Da'im in the Naqsyabandiyah al-Kholidiyah Jalaliyah Congregation, Sheikh Salman Da'im's leadership, as well as Sheikh Salman Da'im's views and actions. Based on the result of this research, Sheikh Salman Da'im is able to merge the functions of Sufism and modernity through the education he produces and the values he teaches which consist of welas asih, dono weweh, andhap asor, wicaksana, as well as his concept for social construction, and preserving religious, social, political harmony and economic development. 

Keywords: Sufism, Islamic values, Leadership, Sheikh Salman Da`im, Tarekat Naqsyabandiyah al-Kholidiyah Jalaliyah

Abstrak: Tarekat dipandang sebagai sesuatu yang tradisional, terkesan menjauhkan diri dari kehidupan modern. Akan tetapi faktanya, kehidupan tidak dapat menghindari modernitas. Oleh karenanya perlu ada keterpaduan antara fungsi sufisme & modernitas. Penerimaan modernitas ini dapat ditemukan dari pemikiran dan nilai-nilai yang diajarkan oleh Syekh Salman Da`im kepada murid-muridnya. Penelitian ini merupakan penelitian kualitatif yang menggunakan pendekatan studi tokoh, mengenai pemikiran dan pengaruh seorang tokoh. Data yang dikumpulkan dari bahan pustaka seperti buku, surat kabar, artikel serta wawancara mendalam dengan menggunakan pertanyaan terbuka. Rumusan masalah dari penelitian ini ialah nilai-nilai kepemimpinan yang diajarkan Syekh Salman Da`im di Lingkungan Tarekat Naqsyabandiyah al-Kholidiyah Jalaliyah, kepemimpinan SyekhSalman Da`im dan pemikiran serta aktifitas Syekh Salman Da`im. Hasil dari penelitian ini adalah bahwa Syekh Salman Da`im dapat memadukan fungsi sufisme dan modernitas melalui pendidikan yang beliau kembangkan, serta dari nilai-nilai yang diajarkan yang meliputi welas asih, dono weweh, andhap asor, wicaksana, dan filosofi dalam membangun umat, serta nilai-nilai dalam merajut kerukunan umat beragama, sosial kemasyarakatan dan politik serta pembangunan ekonomi.
Kata Kunci: Sufisme, Nilai-nilai Islam, Kepemimpinan, Syekh Salman Da`im, Tarekat Naqsyabandiyah al-Kholidiyah Jalaliyah
DOMESTIC TOURISTS’ PERCEPTIONS OF THE INTENTION TO USE DIGITAL MARKETING TOOLS AND PLATFORMS
Authors:   University of Johannesburg, School of Tourism and Hospitality, College of Business and Economics, Johannesburg, South Africa, CHAMBOKO-MPOTARINGA Mavis , TICHAAWA Tembi M. ,   University of Johannesburg, School of Tourism and Hospitality, College of Business and Economics, Johannesburg, South Africa
Published: January 2023

This study built its premise upon the notion that digital technologies have created new bridges for communication between tourists and marketers. The study aims to determine the influence of domestic tourists’ perceptions on the intention to use digital marketing tools and platforms. Based on the Technology Acceptance Model and the updated DeLone and McLean Information Systems, regression analyses were used to test the hypotheses based on 401 surveys conducted with tourists using self-administered questionnaires. Surveys were selected following a non-probability, convenience procedure and stratified proportional sampling technique. The study findings highlight that perceived usefulness, information quality, system quality, service quality and user satisfaction are significantly related to the intention to use digital marketing tools and platforms. The success of digital marketing strategies employed by tourism marketers depends on tourists’ use and adoption of tourism digital marketing tools and platforms. The study findings have policy and practical implications for policymakers, managers and marketers in developing effective and efficient digital marketing strategies that meet tourists’ needs and expectations.