bluuebunny/crossref_metadata_2025 huggingface dataset:
ICTs Use, Agroforestry Technologies’ Adoption and Crop Farmers’ Welfare: An Empirical Evidence from Southwest, Nigeria
Authors: Oparinde Lawrence Olusola
Published: December 2023

There is a glaring shortage of studies on the impact of ICTs use on the adoption of agroforestry technologies and combined effects of ICTs use and agroforestry technologies’ adoption on farmers’ welfare. To fill the information gap, this study examined the impact of ICTs use on agroforestry technologies’ adoption and their heterogenous impacts on crop farmers’ welfare in Southwest, Nigeria. Endogenous-treatment poisson regression (ETPR) model and unconditional quantile regression (UQR) model were used to analyse the data collected from 488 respondents. The results indicated that the use of ICTs improved the adoption of agroforestry technologies which facilitate friendly environment. Also, ICTs use and agroforestry technologies’ adoption statistically and heterogeneously influenced farm revenue and household food insecurity access scale (HFIAS). Precisely, ICTs use had the highest influence on farm revenue at the lowest quantile, while agroforestry technologies’ adoption had the highest effect on household food insecurity access scale (HFIAS) at the lowest quantile. Therefore, policies that promote crop farmers’ access to ICTs should be the priority of policy makers who are interested in the welfare of crop farmers and increased farmers’ level of agroforestry technologies’ adoption.
Agriculture Data Platform – Institutional Data Repository – Selected Aspects
Authors: Stočes Michal , Vaněk Jiří , Jarolímek Jan , Novák Vojtěch , Masner Jan , Šimek Pavel , Kánská Eva , Havránek Martin , Kubata Karel , Voral Vladimír
Published: December 2023

This paper presents selected aspects of a data platform to store agricultural data. It analyses the key user and system requirements for the data platform. The presented aspects were identified through a literature review, interviews and discussions with selected data experts and researchers and future users of the platform. The following issues of the data platform are discussed in the paper: architecture, data types, data source types, metadata, disciplinary interfaces, data sharing, data reusability, Open Science, FAIR data principles, and further data processing options. Part of the knowledge from this article was used in the design and implementation of the Institutional Data Repository called Data Management Platform (DaMP.) CZU (Czech University of Life Sciences Prague) (OPENAI, 2023).
Le rapport à la littérature d’enseignantes du primaire : développement d’outils didactiques et retombées sur les pratiques
Authors: Lépine Martin , Laurence Stéphanie , Émery-Bruneau Judith , Dezutter Olivier , Hétu Suzane , Marcil-Levert Judith
Published: December 2023

Dans le cadre du projet LIBER qui vise à bonifier les pratiques d’enseignement et d’évaluation de la lecture/appréciation d’oeuvres littéraires, nous nous intéressons au rapport que les enseignantes entretiennent avec la littérature. Plusieurs recherches sur le «rapport à…» ont montré qu’il est nécessaire de le considérer afin de faire évoluer les pratiques. Par des entretiens, nous avons questionné les dix enseignantes impliquées dans le projet à propos de cinq dimensions de leur rapport à la littérature. Par une analyse de contenu thématique, nous avons constaté des changements quant à une plus grande intégration de l’oral dans les activités entourant la littérature, l’usage plus marqué de la littérature de jeunesse en classe et du partage plus fréquent des lectures personnelles des enseignantes.
Penser le rapport à l’écriture en lien avec la compétence scripturale
Authors: Lafont-Terranova Jacqueline , Niwese Maurice , Colin Didier
Published: December 2023

Dans une perspective réflexive, nous revenons sur les travaux que nous menons depuis plus de vingt ans sur le rapport à l’écriture pour montrer que cette notion est heuristique et opératoire dans le développement de la compétence scripturale. Nous définissons d’abord notre conception du rapport à l’écriture qui constitue notre ancrage théorique; nous rappelons ensuite les différents outils qui, sur le plan méthodologique, nous ont permis de cerner et de faire évoluer le rapport à l’écriture du sujet-écrivant en contextes de littéracie universitaire, scolaire et non scolaire; enfin, nous rendons compte de résultats saillants qui mettent en lumière l’interdépendance des dimensions du rapport à l’écriture ainsi que leurs liens avec les savoirs et les savoir-faire.
ÉRO : vers une Échelle du Rapport à l’Oral des (futures) personnes enseignantes
Authors: Colognesi Stéphane , Sénéchal Kathleen , Gagnon Roxane , Dupont Pascal , Dumais Christian , Deschepper Catherine , Coppe Thibault
Published: December 2023

Dans cet article, nous présentons la méthodologie de recherche mobilisée pour développer une modélisation et une échelle psychométrique du «rapport à l’oral», baptisée ÉRO (Échelle du Rapport à l’Oral). Nous mentionnons d’abord les grandes étapes du processus, puis nous détaillons les résultats des premières étapes du développement de l’échelle. Elles consistent à décrire le domaine et à définir les dimensions hypothétiques du «rapport à l’oral». Pour ce faire, nous avons utilisé une approche tant déductive (recension des écrits) qu’inductive (entretiens).
Flirting with Things: Simmel on Coquetry and Money
Authors: Bueno Arthur
Published: December 2023

This paper reconstructs Simmel’s arguments on coquetry in light of his Philosophy of Money. There are remarkable similarities between money and flirtation as Simmel understood them. Both are characterized by a paradoxical form of desire for which satisfaction is synonymous with dissatisfaction. Moreover, both are the locus of a specific type of power (i.e., power as pure possibility) and a corresponding kind of submission (experienced as adventure). Yet, unlike money, coquetry can become play for play’s sake. It thus symbolizes life in a different way. Located between economy and art, flirtation permits reconciling opposites that in money appear in maximum tension.
Desde el oficio de ilustrador
Authors: Salmerón Infante Miguel
Published: December 2023

Es reseña de
José Jiménez.
El aprendiz en el sol. Marcel Duchamp y la experiencia de la modernidad
La oficina, Madrid, 2023
ISBN 978-84-124426-3-2
Páginas 208
Some Like it Hot in Communist Romania and Francoist Spain
Authors: Zimbroianu Cristina
Published: December 2023

Resumen
Las películas norteamericanas fueron una gran inspiración, especialmente para los espectadores que tuvieron que vivir bajo regímenes totalitarios. Representaban los valores capitalistas que eran la puerta de entrada al mundo occidental. En la Rumania comunista, estas películas se estrenaron principalmente a mediados de los años sesenta y setenta, y en España desde los años sesenta hasta el final del régimen franquista en 1975. Sin embargo, no todas las películas de Hollywood fueron bien recibidas en estos países, ya que tenían que cumplir las normas de la dictadura comunista en Rumania y las normas católico-nacionales del régimen franquista. Este artículo analiza la recepción de la película de Billy Wilder Some Like It Hot en la Rumania comunista y en la España franquista desde una perspectiva sociocultural de los estudios de traducción, más que desde una perspectiva puramente lingüística que pone de relieve las considerables discrepancias entre los textos, fuente y destino.
Palabras clave: comunismo, franquismo, cine de Hollywood, censura
Abstract
North American films were a great inspiration, especially for viewers who had to live under totalitarian regimes. They represented the capitalist values that were the gateway to the Western world. In communist Romania, these films were released mainly in the mid-1960s and 1970s, and in Spain from the 1960s until the end of the Francoist regime in 1975. However, not all Hollywood films were well received in these countries, as they had to comply with the norms of the communist dictatorship in Romania and the national Catholic rules of the Francoist regime. This article discusses the reception of Billy Wilder’s film Some Like It Hot in Communist Romania and in Francoist Spain from a socio-cultural perspective of translation studies rather than a purely linguistic perspective that highlights the considerable discrepancies between the source and target texts.
Key words: communism, Francoism, Hollywood film, censorship
No hay arte sin piedad Praxis a priori, mythos in medio, poiésis a posteriori
Authors: Corbal Romero José Alberto
Published: December 2023

En este ensayo se analiza la relación entre los conceptos de eulabeia, eusebeia y asebeia, que se pueden traducir como piedad, reverencia e impiedad respectivamente, con los términos praxis, poi?sis y techn?, que se refieren a las distintas formas de acción humana, especialmente en el ámbito de la producción artística, siempre contemplando la característica de la Estética como lenguaje mediador entre el arte para que pueda ser traducido a los espectadores. El objetivo es mostrar cómo la piedad, la reverencia y la impiedad se manifiestan en la praxis, la poi?sis y la techn? artística, y qué consecuencias tienen para el sentido y la función del arte en la sociedad.
Aproximaciones a la Estética Cotidiana
Authors: Navarro Renalias Natxo
Published: December 2023

Reseña de GIOMBINI, L. y KVOKA?KA, A. (eds.) (2021). Everydayness. Contemporary Aesthetic Approaches. Roma: Roma TrE-Press; Prešov: University of Prešov, Faculty of Arts.
Traducción y estética: compatibilidades manifiestas, encuentros necesarios
Authors: Rojo Lemos Patricia
Published: December 2023

La estética y la traducción son disciplinas que surgen de encuentros necesarios y generan compatibilidades manifiestas. En este artículo se exploran las confluencias de ambas disciplinas y se analizan las contribuciones de los autores del  monográfico.
La desautomatización fraseológica como forma de escritura creativa en ELE
Authors: Rodríguez Pablo Ramírez
Published: December 2023

El uso y comportamiento de unidades fraseológicas plantea, a menudo, una serie de dificultades en el aula de ELE debido a las manipulaciones creativas que llevan a cabo los hablantes nativos de una lengua. En este contexto surge el fenómeno de la desautomatización fraseológica mediante modificaciones semánticas, fruto del juego que se establece entre la lectura figurada y literal en contextos determinados. Por otro lado, el acercamiento de los estudiantes universitarios a la literatura en su comprensión escrita también puede llevarse a cabo a través de la práctica creativa. En este sentido, la escritura creativa puede resultar una actividad de gran interés pedagógico, ya que ofrece la posibilidad de expresión artística a través del lenguaje. En respuesta a tal interés nace el objetivo de esta investigación de cara a explorar las posibilidades creativas del lenguaje en materia fraseológica. Asimismo, este estudio pretende examinar una muestra de escritura creativa en contextos fraseológicos dirigida a alumnos universitarios rusos de ELE. Para ello, se recurre a una metodología de estudio de caso mediante el análisis de locuciones verbales en contextos de desautomatización fraseológica. A partir de la desautomatización que sufre la fraseología se intenta acercar a los estudiantes a la puesta en práctica de la creación literaria que permite estimular la creatividad del lenguaje y desarrollar la competencia escrita mediante la producción de textos en la lengua meta.
French and English Texts of the Laws of Oléron: Assessing Proximity between Copies and Editions by Means of Cosine Similarity
Authors: Lis Kinga , Wójcik Jerzy
Published: December 2023

The Laws of Oléron are a compilation of regulations
concerning sea conduct drawn up in the thirteenth century in French. Copies of
the text appeared in varieties of French in England and on the Continent, but it
was only in the sixteenth century that the code was translated into English.
Multiple issues concerning this English text are still vague. An attempt at
settling some of them, such as the relationship between different exemplars and
determining their French source text, has been undertaken in two recent studies.
This article tries to verify whether the conclusions reached there can be
corroborated with the use of mathematical methods of analysis, and to measure
the correlations between the extant copies of the English translation and a
group of French texts named by different researchers as the source texts for the
rendition. The analysis is conducted by means of text similarity measurements
using cosine similarity.
Diez cosas que odio de las listas (ordenadas de menos a más)
Authors: Roig Antoni
Published: December 2023

Llegamos al final de año y proliferan las listas con el resumen de lo más destacado en todos los aspectos de nuestra vida. Listas de todo tipo, en todos los ámbitos. Tenemos realmente una relación curiosa con las listas, objeto de polémicas inacabables sobre qué queda dentro, qué fuera y por qué ese orden y no otro. ¿Por qué son tan populares las listas? En mi caso, mi relación con las listas es complicada, y a ellas dedico este artículo.
Greenhouse gas emissions from natural ecosystems of the Norilsk Industrial District
Authors: Kazantsev Vladimir Sergeevich , Krivenok Lyudmila Alekseevna , Cherbunina Mariya Yur'evna , Kotov Pavel Igorevich
Published: December 2023

This paper describes the results of field measurements of methane and carbon dioxide fluxes from natural and anthropogenic-modified ecosystems located on the Norilsk industrial district. Previously, such studies have not been conducted in the area. The study points are located in different landscape regions determined by various conditions of permafrost formation. Most of the study area is located within the zone of predominantly continuous permafrost distribution. Six landscape regions were identified. Methane and carbon dioxide fluxes were measured at selected key sites typical for each region. When selecting the study points, the variety of conditions affecting methane and carbon dioxide emissions was considered. First, these include soil type (mineral or peat) and local moisture conditions. Methane and carbon dioxide fluxes were measured by dart static chamber method. Measurements of greenhouse gas concentrations in the chamber were carried out by a portable gas analyzer Li-7810 (Li-COR, USA). The results obtained show significant variability in greenhouse gas emissions for different ecosystem types. Methane uptake by soils is recorded on mineral soils and dry parts of bog ecosystems. Positive methane emissions are typical for watered areas of bog ecosystems and lakes with maximum values in the hollows. Methane fluxes range from slightly negative in dry bog areas with a median of -0.026 mgCH4/m2/h to emissions of 0.802 mgCH4/m2/h as the median for watered areas of bog ecosystems. Carbon dioxide fluxes are inversely correlated with the ecosystem moisture content and have a range from 51.6 mgCO2/m2/h (median for lakes) to 576 mgCO2/m2/h (median for mineral soils). A medium strength correlation was found between surface air temperature and intensity of methane uptake by mineral soils was found. Probability density distributions of methane and carbon dioxide fluxes have different forms.
Preliminary Results of Methodology for Forecasting the Minimum Virtual Height of Ionospheric F-Region for Sofia City
Authors: Bojilova Rumiana , Mukhtarov Plamen
Published: December 2023

Using the virtual height for the calculation of the minimum and maximum usable frequency of a given radio path is well known. The purpose of the present investigation is to illustrate a methodology for determining the values of the minimum virtual height (h’F) of the ionospheric F-region. The dependence of the entire ionosphere on the level of solar activity is one of the main factors in the empirical modelling of the ionosphere. Correlation analysis was used to assess the relationship between the quantities. The results show a significant correlation, confirming the well-known relationship between solar activity and its impact on the ionosphere. In order to analyze the most appropriate dependence between the solar activity represented by F107 and h’F, a regression analysis was performed by month. The results show that the optimal dependence is close to linear. As a result, an empirical median model for forecasting h’F for the territory of Sofia city, depending on solar activity and season, is proposed. In its concluding part, this study also presents examples of the model's performance in selected months. The resulting errors are ME=0.000 km and RMS=8.180 km, respectively, which is accurate enough for practical purposes.
An Optimized Cluster Head Selection and Secured Wireless Sensor Network Using MRSA
Authors: Jancy Yesu , Gomathy Balasubramanian
Published: December 2023

Currently, Wireless Sensor Networks (WSNs) play a vital role in remote monitoring and sharing of information in an infrastructure. Even though WSNs have numerous advantages, their usage is reduced by node's lifetime and data loss. The aforementioned problems in WSNs were overcome by using energy efficient protocols by various researchers. But most of the authors focused on either trust model or energy efficient model, or analyzed both models using separate algorithms. However, this leads to repeated process and to high energy consumption. Here, the cluster head is selected by using the swarm intelligence algorithm and LEACH protocol. The hybrid ant colony and modified Particle swarm algorithm are used to select the cluster heads. The CH selection depends on the two parameters, namely residual energy and number of successful transmissions of node. The node's trust is assessed using these two parameters (transmission nodes and residual energy), which also assist in ensuring the safety of the data and energy. The proposed system uses a digital signature algorithm known as the modified RSA algorithm to achieve network security when performing cryptography on data. The performance obtained by the proposed method was compared to other existing techniques in terms of throughput, energy consumption, packet delivery ratio, and network lifetime.
Changes in Colour and Myoglobin Oxidation in Chicken Meat as Affected by Antioxidants during Storage
Authors: Dimitrov Nikolay , Miteva Daniela , Dimov Krasimir , Petkov Evgeni , Popova Teodora
Published: December 2023

The study aimed to investigate the effect of natural antioxidants derived from plants on the changes of colour, pH and myoglobin oxidation of chicken meat during storage. Samples of breast and thighs were divided in three groups – control (C), and treated with infusion of wild basil (T1) or oregano (T2). The meat was stored at 4 °C for 7 days and then at –20 °C up to day 90. The pH, colour, oxymyoglobin (OMb) and metmyoglobin (MetMb) were measured at 0 d, 7 d and 90 d. The antioxidant treatment affected the colour parameters of the chicken meat, as the effect differed according to the muscles and duration of storage. Contrary to breast that exhibited initially decreased yellowness (b*), in T1, the antioxidant treated thigh meat had increased lightness (L*) at 7 d and 90 d, increased b* at 0 d and decreased redness (a*) at 7 d. Duration of storage affected both breast and thigh meat colour, more visible in T1 and T2. Considerable increase in b* was observed in breast, while in thigh meat storage was associated with higher L* and lower a*. Both breast and thigh of the treated groups showed decrease in pH, particularly in the initial stages of storage. The percentage of OMb and MetMb in meat was less affected by the antioxidants. Their effect was stronger in breast, with lower OMb in T1 at the 90th day of storage. Furthermore, this group exhibited dramatic decrease in the OMb in the course of storage. MetMb increased in C and T1 during the storage period. The changes in the myoglobin redox forms in thigh meat are mainly due to storage and are similar to those observed in breast.
Commensal bacteria maintain a Qa-1b-restricted unconventional CD8+ T population in gut epithelium
Authors: Guan Jian , Peske J David , Manoharan Valerio Michael , Park Chansu , Robey Ellen A , Sadegh-Nasseri Scheherazade
Published: December 2023

Intestinal intraepithelial lymphocytes (IELs) are characterized by an unusual phenotype and developmental pathway, yet their specific ligands and functions remain largely unknown. Here by analysis of QFL T cells, a population of CD8+ T cells critical for monitoring the MHC I antigen processing pathway, we established that unconventional Qa-1b-restricted CD8+ T cells are abundant in intestinal epithelium. We found that QFL T cells showed a Qa-1b-dependent unconventional phenotype in the spleen and small intestine of naïve wild-type mice. The splenic QFL T cells showed innate-like functionality exemplified by rapid response to cytokines or antigens, while the gut population was refractory to stimuli. Microbiota was required for the maintenance, but not the initial gut homing of QFL T cells. Moreover, monocolonization with Pediococcus pentosaceus, which expresses a peptide that cross-activated QFL T cells, was sufficient to maintain QFL T cells in the intestine. Thus, microbiota is critical for shaping the Qa-1b-restricted IEL landscape.
Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase
Authors: Boulet Manon , Gilbert Guerric , Renaud Yoan , Schmidt-Dengler Martina , Plantié Emilie , Bertrand Romane , Nan Xinsheng , Jurkowski Tomasz , Helm Mark , Vandel Laurence , Waltzer Lucas
Published: December 2023

N6-methyladenine (6mA) DNA modification has recently been described in metazoans, including in Drosophila, for which the erasure of this epigenetic mark has been ascribed to the ten-eleven translocation (TET) enzyme. Here, we re-evaluated 6mA presence and TET impact on the Drosophila genome. Using axenic or conventional breeding conditions, we found traces of 6mA by LC-MS/MS and no significant increase in 6mA levels in the absence of TET, suggesting that this modification is present at very low levels in the Drosophila genome but not regulated by TET. Consistent with this latter hypothesis, further molecular and genetic analyses showed that TET does not demethylate 6mA but acts essentially in an enzymatic-independent manner. Our results call for further caution concerning the role and regulation of 6mA DNA modification in metazoans and underline the importance of TET non-enzymatic activity for fly development.
Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER
Authors: Yeo Jeremy C. , Tay Felicia P. , Bennion Rebecca , Loss Omar , Maignel Jacquie , Pons Laurent , Foster Keith , Beard Matthew , Bard Frederic
Published: December 2023

Botulinum neurotoxin A (BoNT/A) is a highly potent proteolytic toxin specific for neurons with numerous clinical and cosmetic uses. After uptake at the synapse, the protein is proposed to translocate from synaptic vesicles to cytosol. Surprisingly, we found that after intoxication proteolysis of a fluorescent reporter occurs in the neuron soma first and then centrifugally in neurites. To investigate the molecular mechanisms at play, we use a genome-wide siRNA screen in genetically engineered neurons and identify over three hundred genes. An organelle-specific split-mNG complementation indicates BoNT/A traffic from the synapse to the soma-localised Golgi in a retromer dependent fashion. The toxin then moves to the ER and appears to require the Sec61 complex for retro-translocation to the cytosol. Our study identifies genes and trafficking processes hijacked by BoNT/A, revealing an unexpected complex route for efficient intoxication.
Dialektala möten i skolmiljö
Authors: Jansson Denny
Published: December 2023

I denna artikel undersöks hur ungdomar på två olika yrkesförberedande gymnasieprogram på en gymnasieskola talar om och talar på dialekt i ett geografiskt område där dialekten länge har haft hög kulturell och social status. Två fokusgruppssamtal analyseras för att undersöka både vilka uppfattningar om – och attityder till – dialekter och dialektalt språkbruk som uttrycks samt vilka dialektala varianter som deltagarna själva använder när de samtalar med varandra. Med utgångspunkt i en innehållsanalys och en dialektal språklig analys visar resultaten att deltagarna uttrycker tämligen bestämda uppfattningar om och attityder till dialektalt språkbruk, att en majoritet av dem betraktar dialekten som sin egen och att de även är stolta över den. Resultaten visar även att ungdomarna tenderar att positionera sig själva genom att hänvisa till den egna dialekten och uppfattningar om vem som är typisk dialekttalare. Den språkliga analysen visar hur ungdomarna även använder ett stort antal dialektala varianter när de diskuterar dialekter med andra ungdomar.
“I’ll take it with me all my life”
Authors: Akslen Åse Nylenna , Ohm Modgun , Hu Aihua
Published: December 2023

Substantial evidence has proved that teacher identity significantly influences teachers’ beliefs and choice of actions in their work, and teacher education contributes to the formation and development process. Based on the findings from analysing student teachers’ pedagogical creeds, this article explores the professional identity development of student teachers who have taken an international course at a Norwegian university. The major data sources are the participants’ pedagogic creeds, supplemented by focus-group interviews with one cohort of students. Findings indicate that identity development is an ongoing process, which can be influenced by different factors. Findings also show that the international course has a positive impact on student teachers’ identity development while writing a pedagogic creed can serve as a dialogical tool for their identity development. This case study provides implications for both international and local teacher education programs in Norway and beyond.
HTMC: hierarchical tolerance mask correspondence for human body point cloud registration
Authors: Yu Feng , Chen Zhaoxiang , Liu Li , Ren Liyu , Jiang Minghua
Published: December 2023

Point cloud registration can be solved by searching for correspondence pairs. Searching for correspondence pairs in human body point clouds poses some challenges, including: (1) the similar geometrical shapes of the human body are difficult to distinguish. (2) The symmetry of the human body confuses the correspondence pairs searching. To resolve the above issues, this article proposes a Hierarchical Tolerance Mask Correspondence (HTMC) method to achieve better alignment by tolerating obfuscation. First, we define various levels of correspondence pairs and assign different similarity scores for each level. Second, HTMC designs a tolerance loss function to tolerate the obfuscation of correspondence pairs. Third, HTMC uses a differentiable mask to diminish the influence of non-overlapping regions and enhance the influence of overlapping regions. In conclusion, HTMC acknowledges the presence of similar local geometry in human body point clouds. On one hand, it avoids overfitting caused by forcibly distinguishing similar geometries, and on the other hand, it prevents genuine correspondence relationships from being masked by similar geometries. The codes are available at https://github.com/ChenPointCloud/HTMC.
Licencias Creative Commons (CC)
Authors: Sarovic Mira Paula Angélica , Senabre Estrada María Alejandra
Published: December 2023

Presentación del Taller "Licencias Creative Commons (CC)", realizado para la Subdirección de Recursos de Información y Archivos, dando a conocer lo que son las Licencias Creative Commons.
Body Donation Awareness in Eastern Uttar Pradesh: A Cross-sectional Study among Medical Students, Practitioners, and Support Staff
Authors: Gupta Amrita , Anita .
Published: December 2023

Introduction: Cadavers play a crucial role in facilitating the study of anatomy, as a comprehensive understanding of human anatomy necessitates the dissection of human bodies. Additionally, cadavers are utilised for advanced laboratory work, workshops, and the training of surgical science postgraduates. With the rapid proliferation of medical colleges across the nation and the existing institutions striving to increase their student intake, the supply of unclaimed bodies may no longer be adequate to meet the demands of these institutions. Consequently, the necessity for voluntary body donation becomes increasingly pertinent. Aim: To assess the knowledge, attitude, and awareness regarding body donation among 1st-year MBBS students, healthcare professionals/doctors, and non teaching staff of a teaching institution in Eastern Uttar Pradesh, India. Materials and Methods: This was a cross-sectional study conducted at Varun Arjun Medical College and Rohilkhand Hospital, Banthra, Shahjahanpur, Uttar Pradesh, India. The total number of study participants (n=230) was divided into three groups: 1st-year MBBS students (n=90), healthcare professionals/ doctors (n=70), and non teaching staff (n=70). A self-designed and structured questionnaire containing 15 questions was used in the study. Data were recorded in an Excel sheet and analysed using Statistical Package for Social Sciences (SPSS) Version 26.0 (Chicago, Inc, USA). Results: In the MBBS and Doctors groups, all participants demonstrated familiarity with the study topic, while 95.7% of the non teaching group reported being unacquainted with the concept of body donation. Regarding the purpose of body donation, both MBBS students and Doctors indicated the dual purposes of organ donation/transplantation and medical teaching and research. Male respondents exhibited a notably positive attitude (96.6%) towards both purposes without reservation, while females showed a stronger inclination towards organ donation. When questioned about the procedure for donating the body, the MBBS students and non teaching staff displayed a lack of awareness regarding the process, with 89.5% of doctors being knowledgeable about the donation procedure. Conclusion: Despite the considerable level of awareness regarding body donation, there exists a notable lack of motivation, which could be addressed through effective sensitisation and education initiatives. Enhancing the scenario of insufficient body donations could be accomplished through targeted awareness campaigns utilising both print and electronic media.
Elements of E-Learning that Facilitate or Hinder Learning Motivation: A Review
Authors: Jrall Reecha , Kiran
Published: December 2023

A new way of teaching has been spawned in the wake of the rapid growth of sophisticated technology. Digital technologies in some way enable the teachers to create teaching material that is more interesting because the learning is tailored to the needs of the students related to their upcoming professional workplaces. Moreover, students can easily and efficiently find learning materials by utilizing digital technology in the classrooms. Student participation in the classroom is increased, as is collaboration within the class. This can allow the student's proficiency to improve. Also, integrating digital technology in the classroom can create an enjoyable teaching-learning process, resulting in a positive attitude to learners, and they become motivated to participate in learning activities.  Students can also become distracted or digress when using digital technology in English for Specific Purpose classrooms, for example, when using YouTube or smartphones in the learning process. As we know motivation is the key factor behind learning especially in educational institutions where teachers are the only source of motivation but through the interventions of digital technology learning become e-learning. In electronic teaching learning system presence of teacher is there but what are the other motivational factors in e – learning system that reinforces the learning of students. In the backdrop of this present paper explored the elements in e-content and e learning that act as a motivational element for students in virtual teaching learning process. in this paper researcher conducted a meta-analysis of the past researches conducted on e- learning and motivation. The results of the study points out that e-content and e-learning having interactive features like animation, better organization, collaborative features enhance the learning motivation of students.
Body Core Temperature After Foot Immersion and Neck Cooling in Older Adults Exposed to Extreme Heat
Authors: Meade Robert D. , McCourt Emma R. , McCormick James J. , Boulay Pierre , Sigal Ronald J. , Kenny Glen P.
Published: December 2023

This randomized study evaluates the hypothesis that foot immersion in cool water alone or with supplemental neck cooling mitigates increases in core temperature in older adults exposed to environmental conditions simulating deadly heat waves in North America.
“Rectal Feeding”—Unethical Medical Officer Participation at CIA Secret Interrogation Facilities
Authors: Crosby Sondra S. , Glantz Leonard H.
Published: December 2023

This Viewpoint discusses recently released information regarding the practice of “rectal feeding” among detainees at Guantanamo Bay and Central Intelligence Agency (CIA) secret prisons.
Bilateral Acute Iris Transillumination After Systemic Moxifloxacin Treatment
Authors: Ng Hannah W.
Published: December 2023

This case report discusses a diagnosis of bilateral acute iris transillumination secondary to systemic antibiotics in a patient who presented with persistent bilateral photophobia.
Iris Neovascularization After Vitreous Metastasis of a Cutaneous Melanoma
Authors: Leone Gaia , Nassisi Marco , Viola Francesco
Published: December 2023

This case report describes iris neovascularization secondary to vitreous metastasis of a cutaneous melanoma in a man aged 75 years who presented with elevated intraocular pressure.
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production
Authors: Adusumilli Sri Harsha , Alikkam Veetil Anuthariq , Choudhury Chinmayee , Chattopadhyaya Banani , Behera Diptimayee , Bachhawat Anand Kumar
Published: December 2023

Isoprenoid biosynthesis has a significant requirement for the co‐factor NADPH. Thus, increasing NADPH levels for enhancing isoprenoid yields in synthetic biology is critical. Previous efforts have focused on diverting flux into the pentose phosphate pathway or overproducing enzymes that generate NADPH. In this study, we instead focused on increasing the efficiency of enzymes that generate NADPH. We first established a robust genetic screen that allowed us to screen improved variants. The pentose phosphate pathway enzyme, glucose 6‐phosphate dehydrogenase (G6PD), was chosen for further improvement. Different gene fusions of G6PD with the downstream enzyme in the pentose phosphate pathway, 6‐phosphogluconolactonase (6PGL), were created. The linker‐less G6PD‐6PGL fusion displayed the highest activity, and although it had slightly lower activity than the WT enzyme, the affinity for G6P was higher and showed higher yields of the diterpenoid sclareol in vivo. A second gene fusion approach was to fuse G6PD to truncated HMG‐CoA reductase, the rate‐limiting step and also the major NADPH consumer in the pathway. Both domains were functional, and the fusion also yielded higher sclareol levels. We simultaneously carried out a rational mutagenesis approach with G6PD, which led to the identification of two mutants of G6PD, N403D and S238QI239F, that showed 15–25% higher activity in vitro. The diterpene sclareol yields were also increased in the strains overexpressing these mutants relative to WT G6PD, and these will be very beneficial in synthetic biology applications.
Construction of Multi‐Module RNA Nanoparticles Harboring miRNA, AIE, and CH6 Aptamer for Bone Targeting and Bone Anabolic Therapy
Authors: Cai Bolei , Dong Jiachen , Su Bo , Yang Qiutong , Wang Chenrui , Yang Luying , Song Zhongchen , Liu Jiang , Jin Ronghua , Li Yan
Published: December 2023

Bone healing remains a major challenge in the treatment of osteoporosis. Effective strategies that simultaneously promote bone formation and inhibit bone resorption are crucial for the treatment of osteoporosis and associated bone defects. MicroRNA (miRNA)‐based approaches aim at simultaneously promoting bone formation and suppressing bone resorption and have therapeutic potential. However, the toxicity of cationic carriers and off‐target effects are two major challenges associated with miRNA delivery. This study establishes a bone‐targeting miRNA delivery system (CH6‐SNA‐26a) that integrates aggregation‐induced emission (AIE), a CH6 aptamer, and miRNAs into a single nanoplatform without any cationic carrier. In this system, an AIE molecule is coupled to miR‐26a to form a core–shell spherical nucleic acid (SNA‐26a). The CH6 aptamer is co‐assembled with the SNA to achieve specific miR‐26a delivery to the bone surface. This aptamer‐functionalized, non‐cationic miR‐26a delivery strategy (CH6‐SNA‐26a) enables both bone‐targeted delivery and high transfection efficiency, ultimately optimizing bone remodeling and calvarial bone healing in an osteoporosis mouse model while limiting adverse effects in non‐skeletal tissues. Mechanistically, the overexpression of CH6‐SNA‐26a in skeletal tissues promotes bone anabolic action by functionally targeting glycogen synthase kinase 3 beta in bone marrow mesenchymal stem cells and cellular communication network 2 in osteoclasts.
Great Challenges and New Paradigm of The In Situ Polymerization Technology Inside Lithium Batteries
Authors: Zhang Shenghang , Xie Bin , Zhuang Xiangchun , Wang Shitao , Qiao Lixin , Dong Shanmu , Ma Jun , Zhou Qian , Zhang Huanrui , Zhang Jianjun , Ju Jiangwei , Xu Gaojie , Cui Zili , Cui Guanglei
Published: December 2023

In situ polymerization technology is expected to empower the next generation high specific energy lithium batteries with high safety and excellent cycling performance. Nevertheless, the large‐scale commercial applications of most reported in situ polymer electrolytes are still full of challenges. Owing to the severe parasitic reactions caused by residual monomers, additional initiators and oligomers, lithium batteries using in situ polymer electrolytes often demonstrate limited specific capacity, poor cycling performance, and insufficient rate capability. However, this issue has not received adequate attention in previous reports. Furthermore, the design and evaluation of in situ polymer electrolytes still lack effective guidance and unified standards. Herein, the development history of in situ polymer electrolytes are systematically reviewed and critically disclose the great challenges. Then, from the aspects of monomers, initiators, separators, manufacturing technologies, safety and cycle life evaluation, unprecedentedly a new paradigm is provided for upgrading the in situ polymerization technology inside lithium batteries. It is hoped the novel paradigm will prompt much more insightful studies, expediting the commercialization of in situ polymerization technology in lithium batteries.
A Stretchable and Strain‐Limiting, Bio‐Inspired Nanofiber‐Reinforced Microfiber for Wearable Electronics
Authors: Hanif Adeela , Park Junho , Kim Dohui , Youn Jaeseung , Jeong Unyong , Kim Dong Sung
Published: December 2023

With existing fiber‐based approaches for wearable electronics, devices with limited stretchability are not fully protected against large stretching when the wearer is participating in vigorous activities. A network of elastin and collagen fibers makes biological tissues elastic at low strains and strain‐limiting at high strains, showing a J‐shaped stress‐strain behavior. Stretchable systems can replicate a “J‐shaped stress‐strain/strain‐limiting” mechanical behavior of biological tissues under deformations and provide mechanical compliance and comfort to wearers. For mimicking this mechanical behavior of biological tissues, he developed a combined microfiber and nanofiber (NF)‐based approach. The soft polyurethane (PU) microfiber mimicking elastin of biological tissue is wrapped with stiff poly(vinylidene fluoride)(PVDF) NFs, mimicking collagen in tissue, and dip coated in polydimethylsiloxane (PDMS). Confocal images during stretching confirmed that the PU microfiber maintained stretchability, while the stiff PVDF NFs played a role in the strain‐limiting characteristics. By tailoring a loading ratio of the PVDF NFs on the PU microfiber, the elastic modulus is matched well with those of biological tissues. The stretchable conducting coating and temperature sensor on the bio‐inspired microfiber showed a negligible difference in a current‐time (I‐T) response during static and dynamic stretching which indicated the efficient absorption of stress by the bio‐inspired microfiber.
Biomimetic Small Intestinal Peristalsis Simulator Using Circumferential Pneumatic Artificial Muscles (cirPAM)
Authors: Peerlinck Sam , Willemyns Frauke , Reynaerts Dominiek , Gorissen Benjamin
Published: December 2023

Surgical simulators offer clinicians an environment to train techniques before transitioning to on‐patient procedures. The realism with which a certain procedure can be mimicked is limited by the used simulator model. While for certain procedures surgical simulators are well established, other procedures lack a sufficiently realistic hardware model. The field of soft robotics is especially suited to act as a platform for developing soft tissue surgical simulators, matching both stiffness and extent of deformation of biological soft tissue. Here, an integrated, pneumatically actuated intestinal peristalsis simulator is developed that mimics a section of the small intestines. This simulator is able the mimic both the peristalsis functionality and the intestinal morphology. The simulator incorporates novel circumferential pneumatic artificial muscles (cirPAM) that radially contract and expand when exposed to respectively negative and positive pressures while keeping their cross‐sectional thickness constant. By sequencing the inflation of these cirPAM actuators, a global peristaltic motion is created with a peristaltic wave propagating at 20 mm s −1, which is in accordance with human physiology. Finally, the simulator is shown to pump viscous liquids, confirming that besides the morphological semblance, it also functionally resembles human small intestine, and can offer a platform for medical device testing and surgical training.
Tolerant and Rapid Endochondral Bone Regeneration Using Framework‐Enhanced 3D Biomineralized Matrix Hydrogels
Authors: Bai Baoshuai , Liu Yanhan , Huang Jinyi , Wang Sinan , Chen Hongying , Huo Yingying , Zhou Hengxing , Liu Yu , Feng Shiqing , Zhou Guangdong , Hua Yujie
Published: December 2023

Tissue‐engineered bone has emerged as a promising alternative for bone defect repair due to the advantages of regenerative bone healing and physiological functional reconstruction. However, there is very limited breakthrough in achieving favorable bone regeneration due to the harsh osteogenic microenvironment after bone injury, especially the avascular and hypoxic conditions. Inspired by the bone developmental mode of endochondral ossification, a novel strategy is proposed for tolerant and rapid endochondral bone regeneration using framework‐enhanced 3D biomineralized matrix hydrogels. First, it is meticulously designed 3D biomimetic hydrogels with both hypoxic and osteoinductive microenvironment, and then integrated 3D‐printed polycaprolactone framework to improve their mechanical strength and structural fidelity. The inherent hypoxic 3D matrix microenvironment effectively activates bone marrow mesenchymal stem cells self‐regulation for early‐stage chondrogenesis via TGFβ/Smad signaling pathway due to the obstacle of aerobic respiration. Meanwhile, the strong biomineralized microenvironment, created by a hybrid formulation of native‐constitute osteogenic inorganic salts, can synergistically regulate both bone mineralization and osteoclastic differentiation, and thus accelerate the late‐stage bone maturation. Furthermore, both in vivo ectopic osteogenesis and in situ skull defect repair successfully verified the high efficiency and mechanical maintenance of endochondral bone regeneration mode, which offers a promising treatment for craniofacial bone defect repair.
Crystallography of Active Particles Defining Battery Electrochemistry
Authors: Morley John Donald , George Chandramohan , Hadler Kathryn , Brito‐Parada Pablo R.
Published: December 2023

Crystallographic features of battery active particles impose an inherent limitation on their electrochemical figures of merit namely capacity, roundtrip efficiency, longevity, safety, and recyclability. Therefore, crystallographic properties of these particles are increasingly measured not only to clarify the principal pathways by which they store and release charge but to realize the full potential of batteries. Here, state‐of‐the‐art advances in Li+, K+, and Na+ chemistries are reviewed to reiterate the links between crystallography variations and battery electrochemical trends. These manifest at different length scales and are accompanied by a multiplicity of processes such as doping, cation disorder, directional crystal growth and extra redox. In light of this, an emphasis is placed on the need for more accurate correlations between crystallographic structure and battery electrochemistry in order to harness crystallographic beneficiation into electrode material design and manufacture, translating into high‐performance and safe energy storage solutions.
Organocatalytic Chemoselective C4‐Benzylation of 5‐Aminopyrazoles
Authors: Natarajan Pradeep , Kanchithalaivan Selvaraj , Chatterjee Arpita , Peruncheralathan Saravanan
Published: December 2023

The first chemoselective C4‐benzylation of 5‐aminopyrazoles, utilizing a 3 mol% squaric acid catalyst, is disclosed. In this process, ortho‐quinone methides are efficiently generated from 2‐hydroxybenzyl alcohols in water under mild conditions. This method successfully delivers a wide range of C4‐benzylated 5‐aminopyrazoles, achieving moderate to excellent yields while demonstrating high chemoselectivity, which is further confirmed by mechanistic studies. Notably, the protocol uses water as an eco‐friendly solvent, requires a low organocatalyst loading, and eliminates the need for column chromatography.
Cell‐Penetrating Peptide‐Bismuth Bicycles**
Authors: Voss Saan , Adair Liam D. , Achazi Katharina , Kim Heeyoung , Bergemann Silke , Bartenschlager Ralf , New Elizabeth J. , Rademann Jörg , Nitsche Christoph
Published: December 2023

Cell‐penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells. We report the first CPPs based on peptide‐bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them accessible for a wide range of applications. These CPPs enter human cells as demonstrated by live‐cell confocal microscopy using fluorescently labelled peptides. We report efficient sequences that demonstrate increased cellular uptake compared to conventional CPPs like the TAT peptide (derived from the transactivating transcriptional activator of human immunodeficiency virus 1) or octaarginine (R8), despite requiring only three positive charges. Bicyclization triggered by the presence of bismuth(III) increases cellular uptake by more than one order of magnitude. Through the analysis of cell lysates using inductive coupled plasma mass spectrometry (ICP‐MS), we have introduced an alternative approach to examine the cellular uptake of CPPs. This has allowed us to confirm the presence of bismuth in cells after exposure to our CPPs. Mechanistic studies indicated an energy‐dependent endocytic cellular uptake sensitive to inhibition by rottlerin, most likely involving macropinocytosis.