bluuebunny/crossref_metadata_2025 huggingface dataset:
Изучение нейропротекторного действия композиции на основе тетрапептида HAEE, цинка и человеческого сывороточного альбумина при моделировании тау-протеинопатии
Authors: Шмигерова Вероника С. , Покровская Татьяна Г. , Корокин Михаил В. , Покровский Михаил В. , Скоркина Марина Ю. , Солин Алексей В. , Радченко Александра И. , Жунусов Никита С. , Щеблыкина Олеся В. , Пересыпкина Анна А.
Published: June 2024

Одним из возможных вариантов фармакологической поддержки при тау-протеинопатии является композиция на основе тетрапептида НАЕЕ (His-Ala-Glu-Glu, гистидил-аланил-глутамил-глутаминовая кислота), цинка и человеческого сывороточного альбумина (Hsa). В исследованиях in vitro композиция HAEE-Zn-Hsa в концентрации 1 мкм (в расчете на пептид) приводила к повышению митохондриальной функции: повышение потребления кислорода OCR от 125,32 до 179,24 пмоль/мин (p < 0,05) и снижению гликолитической активности клеток первичной смешанной культуры гиппокампа мышей P301S у самцов на 84 % и у самок на 44,6 % (p < 0,05), по сравнению с животными контрольных групп. У мышей P301S композиция HAEE-Zn-Hsa (в дозировке 0,01 мг, подкожно в течение 30 дней 1 раз в 2 дня) в тесте «Лабиринт Барнса» вызывала улучшение когнитивных функций: снижение общего расстояния пройденной дистанции на 34,5 % (p ≤ 0,0001), по сравнению с мышами положительного контроля, сокращение латентного времени нахождения на платформе в группе на 77,5 % (p ≤ 0,0001), по сравнению с мышами положительного контроля, увеличивалась скорость передвижения на данной дистанции на 36 % (p ≤ 0,0001), по сравнению с мышами положительного контроля. Применение HAEE-Zn-Hsa и пирацетама (в дозировке 200 мг, подкожно в течение 30 дней 1 раз в 2 дня), при проведении теста «Вертикальный стержень», в первой контрольно-временной точке у мышей не было выявлено статистически достоверных различий между группами, так как отсутствовали проявления симптомов тау-протеинопатии, во второй контрольно-временной точке мыши, получающие композицию HAEE-Zn-Hsa, смогли дольше удерживать равновесие на стержне на 36 % (p ≤ 0,0001), по сравнению с мышами положительного контроля, это указывает на замедление развития заболевания. В результате исследования морфологической картины тау-протеинопатии у мышей P301S с применением HAEE-Zn-Hsa и мышей линии C57Bl/6 были обнаружены сходные особенности в энторинальной коре головного мозга, где нейроны имели преимущественно округлую и пирамидальную форму с везикулярными ядрами. В гиппокампе мышей данных групп наблюдался плотный зернистый ряд нейронов с однонаправленными отростками.
Влияние экстракта сухого Leuzea uniflora (L.) Holub на энергетические и антиоксидантные процессы в головном мозге крыс при длительной алкогольной интоксикации
Authors: Маркова Кристина Владимировна , Разуваева Янина Геннадьевна , Торопова Анюта Алексеевна , Оленников Даниил Николаевич
Published: June 2024

Проведена оценка влияния экстракта сухого Leuzea uniflora на энергетические и антиоксидантные процессы головного мозга крыс линии Вистар в условиях длительной алкогольной интоксикации. Крысы контрольной и опытных групп в течение 6 недель получали 40 % этиловый спирт в дозе 10 мл/кг per os. Начиная с 3-й недели эксперимента, животным опытной группы внутрижелудочно вводили водный раствор экстракта сухого L. uniflora в дозе 100 мг/кг в течение 4 недель. Для оценки функции дыхательной цепи митохондрий замеряли активность NADH-дегидрогеназного и сукцинатдегидрогеназного (SDH) комплексов в ткани головного мозга. Интенсивность процессов перекисного окисления липидов определяли по концентрации малонового диальдегида, уровень антиоксидантной системы – по активности каталазы, супероксиддисмутазы, глутатионпероксидазы, глутатионредуктазы и содержанию восстановленного глутатиона в гомогенате ткани головного мозга. Установлено, что экстракт L. uniflora у крыс при длительной алкогольной интоксикации увеличивает активность NADH-дегидрогеназного комплекса в митохондриях клеток головного мозга в 1,5 раза и активность SDH-комплекса — в 2,0 раза (p ≤ 0,01), повышает активность супероксиддисмутазы (на 31 %), глутатионпероксидазы (на 17 %) и глутатионредуктазы (на 30 %), уровень восстановленного глутатиона (на 17 %), снижает уровень малонового диальдегида на 23 % в гомогенате ткани головного мозга, p ≤ 0,05. Таким образом, экстракт сухой L. uniflora способствует восстановлению энергетических реакций в условиях длительной алкогольной интоксикации, угнетая процессы перекисного окисления липидов, и оказывает положительное действие на эндогенную антиоксидантную систему организма животных.
Education for sustainable development in primary school: Understanding, importance, and implementation
Authors: Lamanauskas Vincentas , Malinauskienė Daiva
Published: June 2024

There is no doubt that education for sustainable development (ESD) is important because it covers all areas: social, emotional, intellectual, physical, moral, etc. ESD helps people acquire the skills, knowledge, and values necessary for a successful life and a constructive contribution to society. If earlier early ESD was not at the centre of attention, recently it has become increasingly clear that early education has great potential for fostering values, behaviours, and skills that contribute to sustainable development. Despite this, ESD remains problematic due to the inadequate preparation of pre-service primary teachers in this area. It is obvious that ESD implementation in primary education is still poorly integrated.

Empirical qualitative research aimed to reveal how pre-service primary school teachers understand ESD in primary school. Generally, 86 students from two Lithuanian universities, pre-service teachers of preschool and primary education, took part in the research. Verbal research data were analysed using the quantitative content analysis method.

The results suggest that although ESD in early childhood is understood as significant and reasonable, however, the understanding of pre-service teachers is rather one-sided. ESD is understood as social welfare, while the natural and physical environment is the least expressed in their understanding structure. Meanwhile, the implementation of ESD is understood as a normal educational process, applying known techniques and methods. It is necessary to strive for the young generation to be characterised by responsibility, a sense of community, conservation, and citizenship, to understand the harmony of the surrounding world and their activities. For that purpose, changes in the education are needed to integrate the necessary ESD elements, including both managerial and educational processes.
التشابه والاختلاف في اللغتين الروسية والعربية
Authors: ا.م.د. حسين كاظم مجدي الدريساوي
Published: June 2024

المستخلص: تناول البحث مسألة الفئات النحوية باللغتين الروسية والعربية، وحدد أوجه التشابه بين اللغتين، وقدم تحليلاً مقارنًا، وعرض فئات الجنس والعدد والحي/الجماد. اكتشف العائلات التي تنتمي إليها اللغتان ولماذا خضعت البنية النحوية للتغيرات بمرور الوقت.  وفحص أوجه التشابه والاختلاف في فئة الرقم بالتفصيل،  وعرض خصائص الرقم المزدوج في اللغتين العربية والروسية القديمة،  وقدم أمثلة من اللغة الروسية القديمة التي كانت متشابهة في الفئات النحوية مع اللغة العربية. تتناول البحث أعمال اللغويين الذين يدرسون النظام النحوي والمعجمي للغات الروسية والروسية القديمة والعربية. وفي نهاية البحث عرضت نتائج الدراسة التي تثبت أوجه التشابه والاختلاف بين اللغتين الروسية والعربية وأسباب تغيرهما.
Effect of Representativeness Bias, Availability Bias and Anchoring Bias on Investment Decisions
Authors: Sumantri Muhammad Bayu Aji , Susanti Neneng , Yanida Pebri
Published: June 2024

This study aims to determine the effect of three types of financial behavioral bias, namely representativeness bias, availability bias, and anchoring bias on investment decisions. This study uses a quantitative method with a purposive sampling technique. Data were collected through questionnaires and analyzed using Structural Equation Modeling (SEM) with the help of SmartPLS 3.0 software. The results of the study show that the two types of financial behavioral bias have a significant effect on investment decisions which are the representativeness bias and the availability bias on investment decisions, while anchoring bias does not have an effect on investment decisions. This research can contribute to investors to better understand the effect of financial behavior bias on investment decisions and to take wiser actions in investing.
A Cultural Evolution Framework for Human Creativity
Authors: Gabora Liane
Published: June 2024

Other species perceive, make decisions, take action, and even create. Our species is exceptional with respect to our predilection to adapt ideas to our own needs, tastes, and perspectives, and express ourselves through language, technology, art, and other means. This short paper summarizes an ongoing program of theoretical and empirical research aimed at establishing a scientific framework for cultural evolution and how it is fueled by creativity, both within-domain but cross-domain. how the creative process works, and how human creativity evolved. What makes this research program unique is that it examines creativity from the perspective of its role in fueling the evolution of culture, and includes both studies. It concludes with a brief discussion of how the creative process works and how this theoretical framework has been applied to the development of computer-generated art and music.
Employment Satisfaction Survey (ESS) in measuring and evaluating employee management expectations
Authors: Lee Christopher M.
Published: June 2024

Professional and Essential Workers that includes blue-colored jobs all over the world truly understands and have their own personal expectations with it comes to the so-called Employment Satisfactions towards their employer career advancement. A desirable career advantages and an employment criterion matrix evaluates different local employees, and other specified workers in order to realize and understands several employment satisfaction component guidelines into their personal career goals and aspirations. From this aspect, the research article is focused on the feedback of the employees whether they are still connected from their companies, and those who are considered outgoing or their separation from their employment.
Manajemen Wakaf
Authors: H Yuris Huswatun
Published: June 2024

Salah satu lembaga ekonomi Islam yang sangat berperan dalampemberdayaan ekonomi umat adalah wakaf. Dalam sejarah, wakaf telahberperan dalam pengembangan sosial, ekonomi, dan budaya masyarakat.Hal-hal yang menonjol dari lembaga wakaf adalah peranan dalammembiayai berbagai kegiatanagama Islam, pendidikan, kesehatan. Kondisiinilah kemudian memerlukan adanya reformasi didalam manajemen danadministrasi harta wakaf.
Implementation of Mapasilaga Tedong Licensing in Tana Toraja District Based on Laws and Regulations
Authors: Awaluddin  , Asriyani  , Ansar  , Rantau Arnesto
Published: June 2024

The problem formulations in this study are: 1) How is the implementation of crowd licence on Mapasilaga Tedong activities in Tana Toraja? 2) How is the supervision of crowd permits for Mapasilaga Tedong activities in Tana Toraja? This type of research in legal research is research that uses empirical juridical methods with a descriptive research approach. The author's conclusion is: The implementation of the crowd permit for Mapasilaga Tedong activities in Tana Toraja is considered not properly implemented. Because there are still many inhibiting factors in terms of processing crowd permits including Socialisation, lack of public understanding of the procedure for applying for a crowd permit, lack of assertiveness in terms of time provisions from the Police in issuing crowd permits, and making crowd permits through practical ways. The supervision of crowd permits for Mapasilaga Tedong activities in Tana Toraja carried out by the Tana Toraja police has not been able to completely eradicate gambling practices in Mapasilaga Tedong activities. There are several factors that become obstacles to eradicating this violation of the law, namely: A) The police have not fully professionally seen and sorted out between culture and law violations that are considered a culture. B) The lack of role of the local government to assist the police in terms of management and supervision with the absence of local regulations related to crowd permits so that there is no harmonisation between the police and the local government of Tana Toraja in terms of management and supervision of crowd permits.
Separated by Degrees: Social Closure by Education Levels Strengthens Contemporary Political Divides
Authors: de Jong Jona , Kamphorst Jonne
Published: June 2024

Note, this article has now been published and can be accessed at (https://journals.sagepub.com/doi/10.1177/00104140241271104). Across Western democracies, education levels are predictive of immigration attitudes and voting for new left or far right parties. What explains education-based political divides? This article proposes that social closure of higher- and lower-educated citizens strengthens and reinforces differences in political attitudes and voting between them. Using social network data from the Netherlands, and ESS data, we show that large proportions of higher- and lower-educated citizens report no close relationships with different education levels. Network education levels, in turn, are predictive of immigration attitudes and voting behaviour. Difference-in-differences models show that a change in network education levels is associated with change in these outcomes. Our findings contribute to literatures on educational divides and peer effects. Moreover, they support an interpretation of political competition on the universalist-particularist dimension as durably rooted in social structure. Sizable, distinct and insulated educational groups can crystallize contemporary divides and predictably shape political reality.
Research Project Submission before Graduation: Knowing its Importance and Understanding among Students and Learners
Authors: Lee Christopher M.
Published: June 2024

The development of this research study article concentrate exclusively within our Students and Learners, just like our facilitators in research medium who completely comprehends the significance and usefulness of why graduating understudies need to agree all through the accommodation of a Practical Research Project before the completion of their educational plan program thoroughly. The Department of Education in the Philippines and it’s affliates initially directs a Curriculum direction and guidelines to ensure that Students & Learners will be inform about the significance and convenience that merely focused on Practical Research Study and to agree in presenting a Research Project before their graduation exercises.
Quadratic Relations and Oblong Parabolic Prime Sieve: A New Approach to Goldbach's Conjecture
Authors: Kusniec Charles
Published: June 2024

This study expands the geometric tool known as the Parabolic Sieve of Primes (PSO) [12] by introducing the Oblong Parabolic Sieve of Primes with Offset (Oblong PSO). This technique, applying an offset to the oblong D-parabola instead of the square D-parabola, facilitates the isolation of primes in the Cartesian plane. We demonstrated that principles applicable to square numbers can equivalently apply to oblong numbers, resulting in the discovery of the C003515 Table of Odd Integers Distributed Along the Center-Aligned Bases of f-Triangles. To address the limitation of non-vertically aligned primes, we developed the C003518 Expanded Table, suggesting consistent vertical prime pairs, thereby supporting Goldbach's Conjecture. The C003519 Quadratic Relations of Prime Pairs Table further explores prime pairs within quadratic sequences. These findings, combined with the study on The Quadratic Distribution of Integers Relative to Squares and Oblongs [13], provide robust evidence for Goldbach's Conjecture. This study adopts the terms 'primals' and 'compounds' for clarity and is a continuation of the Mersenne Forum thread The proof of Goldbach's conjecture and Landau's problem, accessible at https://www.mersenneforum.org/showthread.php?t=28200.
Mission ZeroEmission - A program to decarbonize production sites and the path to a circular economy and management by a PMO
Authors: Glitscher Wolfgang
Published: June 2024

Decarbonization and the conversion of production to circular processes and the use of sustainable raw materials is in the hands of the strategic decision-makers of organizations who want this transformation. The necessary concepts and organizational measures must be put in place in the following steps. The necessary prerequisites for strategic and operational management and thus also for project management are discussed at the beginning and illustrated with examples. Subsequently, the example of an international group with over one hundred production sites worldwide is used to illustrate how this transformation process is managed via a program and a project management office (PMO) over a period of more than ten years. The process is fully digitalized to ensure the necessary monitoring and control.
Calculation of Individual and Product Sustainability under IMACS
Authors: Dert Vincent
Published: June 2024

The methods described allow calculation of individual and product sustainabilities and of human conditions for all products, services and individual labor, in a globally standardized way. Product and service sustainabilities reflect natural resource use, environmental damage done and harmful or inhumane labor and living conditions that existed, to make, transport and sell the product or service. Individual sustainability reflects the degree to which an individual lives sustainable and is determined by the impacts of resource use and damage done due to individual consumption and conservation applied. The methods allow the calculation of product, service and individual sustainabilities per impact variable, for any of a dozen variables distributed over eleven impact groups, for any combination of impacts variables, including the use of a single sustainability value combining all impact variables. The use of a single sustainability value that can be printed on or scanned from the QR code on labels of participating products, makes it easier for consumers to compare and select more sustainable products and services and allows customers to become more sustainable themselves. It will also drive competitors to improve product sustainability, reducing costs and make increasingly more sustainable products available to the public.
The Effect of Colour Contrast on Academic Anxiety and Emotion in Online Testing Environment
Authors: Huang Yiou
Published: June 2024

Colour information widely exists in daily life and has a broad influence on human emotion, and presumably affects digital learning and testing experience. In the present study, we investigated the impact of colour contrast on students’ academic anxiety during online testing. In Experiment 1, we recruited 52 students and asked them to solve an array of verbal and mathematical questions in a computer-based test. The visual background was divided into two parts horizontally (left and right) with different colours. The background switched from high colour contrast (warm-cool) to low colour contrast (warm-warm or cool-cool) during the test, and we measured participants’ academic anxiety levels under each colour contrast condition. Results showed that high colour contrast is associated with higher academic anxiety levels compared with low colour contrast, and the overall colour temperature (i.e., warm or cool) had no significant effect. In Experiment 2, we ruled out the confounding effect of testing order and materials by starting with low colour contrast and including only verbal questions. We replicated our finding that high colour contrast is associated with higher academic anxiety level experienced. These findings reveal a link between colour perception and emotion, guiding for designing online learning and testing environments.
Proximity to settlements in the West Bank shifts protest behaviour towards higher-risk engagement and raises perceived relative deprivation
Authors: Mallock Nils Uwe , Krekel Christian
Published: June 2024

Participation in intergroup conflict has been linked to various predisposing factors, but the role of perceptions, such as of group-oriented relative deprivation (RD), remains empirically contested. Here we examine this hypothesis for protest behaviour in the West Bank. Since the Six-Day War of 1967, civilian Israeli settlements have been established here, making salient stark local inequalities. Across two primary and four secondary data collections (N=8,360), exploiting geographical coordinates, we show that proximity to settlements increased the relative likelihood of participating in higher-risk and violent action (between +41% and +82%) at the cost of lower-risk and moderate protest (-30% to -36%), flanked by similar attitudinal shifts. Effects were spatially limited to a 3-kilometer distance and time-insensitive. Self-reports were also reflected in administrative data on actual protest events during the same period. Moreover, the shift is not explained through past negative contact – instead, we find support for RD as the underlying mechanism, ruling out several alternatives. Our study provides evidence that group proximity can influence engagement behaviour in settings of asymmetrical conflict.
Questionable prospective decreasing effect of internet use on depression: A simulated reanalysis and comment on Liu et al. (2024)
Authors: Sorjonen Kimmo , Melin Bo
Published: June 2024

Based on findings from analyses with cross-lagged panel models, Liu et al. (2024) concluded that internet use can prevent depression among older adults. Here, we simulated data to resemble the data used by Liu et al. We used triangulation and fitted complementary models to the simulated data and found contradicting decreasing, increasing, and null effects of initial internet use on subsequent change in depressive symptoms. These divergent findings suggest that it is premature to assume a decreasing effect of internet use on depression and the conclusion by Liu et al. in this regard can be challenged. It is important for researchers to be aware that correlations, including adjusted cross-lagged effects, do not prove causality in order not to overinterpret findings, something that appears to have happened to Liu et al. We recommend researchers to triangulate by fitting complementary models to their data in order to evaluate if observed effects may be due to true causal effect or if they appear to be spurious.
A Systematic Review and Meta-Analysis of Language and Cognition in the Developing Bilingual Brain: From Infancy to Adolescence
Authors: Leung Kai Ian , Tremblay Pascale , Molnar Monika T.
Published: June 2024

Research investigating the neural mechanisms of language and cognition in bilingual children is steadily growing. We reviewed fMRI and fNIRS studies to identify brain regions engaged during linguistic and cognitive tasks of bilingual compared to monolingual children. Out of 26 eligible studies, six fMRI studies were included into an exploratory coordinate-based meta-analysis, whereas fNIRS papers lacked sufficient statistical and methodological data for meta-analysis. Results suggest that: (1) bilinguals’ neural correlates of language and cognition revealed clusters across classic language areas; however, differences were discerned based on bilinguals’ age of acquisition; (2) comparisons considering bilingual age of acquisition groups and age-matched monolinguals revealed differences in activation within the IFG – sole area identified in the fMRI meta-analysis – among other regions across the frontal, temporal, and parietal lobes. Overall, activation patterns in bilingual children align with those of bilingual adult studies, highlighting involvement of key frontal and temporal regions in language and cognition.
The good, the bad and the improved practices for statistical modelling - A crowdsourcing project
Authors: Coolen Ilse Elise Johanna Ingrid
Published: June 2024

Practices in statistical modelling.Kicking off with the famous George Box words that “all models are bad, but some can be useful”; but how to avoid pitfalls and ensure that a model does indeed fall within the useful category? Statistical modelling is a powerful tool to answer a wide range of research questions and provides valuable insights in understanding complex systems or phenomena. However, in fields such as psychology, most researchers are not statisticians or do not have an expert background in statistical modelling. Whether you are stepping into the realm of modelling for the first time or have been navigating it for a while, chances are that you are self-taught out of curiosity or necessity for your research. The lack of widespread knowledge about this statistical technique results in some common pitfalls that can reduce the quality of the models developed.Therefore, I organised a lab meeting with the Lifespan Cognitive Dynamics Lab, which has a strong focus on statistical approaches such as SEM, linear mixed modelling, mixture modelling and related approaches, with the goal to gather some bad and good practices in modelling. The first aim of this post is to raise awareness and give you the handles to avoid bad practices in statistical modelling and turn them into good ones. The second aim is to invite anyone with additional bad or good practices in statistical modelling, to add their experience to the document.Though this list will not be exhaustive, I hope that other researchers will add their knowledge and I hope it will aid fellow researchers in navigating the complexities of statistical modelling with greater confidence by becoming aware of potential pitfalls.Procedure and insights of the lab meeting.I asked each lab member to prepare at least one bad and one good practice that they had previously encountered or experienced in modelling, which we then categorised in one of 3 categories during the meeting: (A) data handling and pre-processing, (B) model development and selections, and (C) documentation and interpretation. The categories weren’t communicated beforehand to allow out-of-the-box thinking. Each practice was discussed and nuances were added where needed. For each bad practice we tried to come up with a way around it or turn them into a good practice. Each of the practices are explained in more detail. A crowdsourcing project Do you believe there are some crucial practices missing? I invite you to read the guidelines of contributing to this crowdsourcing document and make your suggestions on the editable google doc.We welcome any contributions in the form of additional bad/good/improved practices or modifications/nuances to an existing practice.I will periodically verify the suggestions made and upload a new ReadOnly/preprinted version including your contributions if these are accepted. The new version of the preprint will then be shared on social media (Twitter/BlueSky).
Individual Differences in Subtractive Thinking and Creative Problem-Solving: Evidence for an Association with Convergent but not Divergent Thinking
Authors: Martinez David , Koff Mitchell A , George Tim
Published: June 2024

Recent research suggests that people overlook the option to remove elements when making decisions or solving problems, preferring instead to make additive changes; however, little research has explored individual differences in this tendency to make subtractive changes. This study investigated the relationship between individual differences in creative thinking (via convergent and divergent thinking), and the tendency to suggest subtractive changes. Two-hundred fifty-two participants completed a sample of subtractive, convergent, and divergent thinking tasks. Only convergent thinking was weakly but significantly predictive of subtractive thinking. These results suggest that processes involved in creative cognition are related to subtractive thinking. More research is needed to refine the measurement of individual differences in subtractive thinking as well as to clarify the specific processes underlying the relationship between creative and subtractive thinking.
Computational speech markers of negative symptoms show evidence of being robust to antipsychotic dose and extrapyramidal symptoms in schizophrenia
Authors: Spilka Michael J. , Robin Jessica , Nikzad Amir Hossein , Behbehani Leily , Berretta Sarah , Xu Mengdan , Kane John M. , Simpson William , Tang Sunny X.
Published: June 2024

There is increasing interest in using computational speech and language analysis for the objective assessment of symptom severity in schizophrenia spectrum disorders (SSD), including negative symptom severity. However, the extent to which antipsychotic side effects influence speech markers of negative symptoms is unclear. This study investigated associations between computational speech and negative symptom severity, and examined whether speech features are associated with antipsychotic dose and extrapyramidal symptoms (EPS). Sixty-seven participants with SSD completed speech-focused tasks and clinical assessment. Seventeen speech features capturing relevant acoustic, timing, and linguistic characteristics were extracted from participant responses and examined for associations with negative symptoms, EPS, and antipsychotic dose. Eight timing features and one linguistic feature were significantly correlated with negative symptom severity (p < .05, false-discovery-rate-corrected; FDR), and these relationships were specific to negative symptoms rather than overall psychiatric symptom severity. No features were significantly correlated with antipsychotic dose or EPS after FDR correction, and Bayesian analyses provided moderate evidence for the null hypothesis (i.e., absence of an association) for most features. Two features showed Bayesian evidence for the alternative hypothesis, however; the association between speech and negative symptoms remained significant after removing the clinical covariate effects. The results provide support for computational speech markers of negative symptom severity, and both frequentist and Bayesian evidence that these speech markers are generally not confounded by antipsychotic side effects. The results help advance the clinical validation of computational speech assessment and analysis for measuring negative symptom severity in SSD.
Riesgo de crédito: Evidencia en la banca múltiple peruana
Authors: Echegaray Roldán Victor
Published: June 2024

Este estudio tiene como fin investigar los factores que determinan el riesgo de crédito en la banca múltiple peruana. Se explora la relación de las variables macroeconómicas y específicas del banco frente al riesgo de crédito, las cuales fueron analizadas a través de un conjunto de datos de panel que incluyeron 185 observaciones de la banca múltiple durante los años 2001 – 2019. Basados en varias pruebas robustas, los resultados sugieren que el tipo de cambio y la tasa de referencia de la política monetaria nacional son significativamente positivos al riesgo de crédito de la banca múltiple peruana, mientras que la eficiencia bancaria, la rentabilidad sobre el patrimonio (ROE), el crecimiento de los préstamos, poder de mercado y producto bruto interno (PBI), muestran una relación significativamente negativa al riesgo crediticio de la banca. El resultado de este estudio provee evidencia de que el riesgo de crédito fue influenciado por variables macro y micro (específicas del banco) juntas.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1601
La planificación participativa en la gestión del territorio: el caso de la Parroquia Malchinguí en Ecuador
Authors: Guanoluiza Llive Myrian , Raza Carrillo Diego
Published: June 2024

El propósito de esta investigación es describir la evolución y estado del proceso participativo de planificación llevado a cabo por los habitantes de Malchinguí en Ecuador para la gestión de su territorio en los últimos años. A partir de un paradigma investigativo pragmático y con un método inductivo se realiza un estudio de corte descriptivo y transversal que a partir de la observación y descripción de la situación particular del proceso de planificación participativa del territorio en Malchinguí reflexiona sobre la importancia de estos procesos en general en las parroquias rurales de Ecuador. El principal resultado de esta investigación es la confirmación de que la evolución del carácter participativo de los procesos de planificación del territorio en Malchinguí ha determinado una mejor selección de proyectos a incluir en sus planes de desarrollo y ordenamiento territorial, un mayor compromiso de su ciudadanía con su propio desarrollo y una adecuada y mejor priorización en la ejecución de los planes de desarrollo territorial y sus correspondientes proyectos.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1603
Modelo de gestión estratégica para el Observatorio de Ciencias Empresariales de la Universidad de Otavalo
Authors: Andrade Orbe Adrián , Perugachi Limaico Lizandro , Morocho Terán Johanna , Perugachi Limaico Nelly
Published: June 2024

La forma en que la educación superior adopta un enfoque estratégico para lograr efectividad en sus servicios, permitió determinar como objeto de estudio el modelo de gestión estratégica y el campo de estudio el Observatorio de Ciencias Empresariales de la Universidad de Otavalo. En este sentido se pudo determinar que la gestión en la educación superior busca obtener ventajas competitivas mediante una posición única y valiosa en el mercado. El enfoque aplicado fue mixto, integra elementos sistemáticos empíricos y críticos para la recolección y análisis de datos cuantitativos y cualitativos que se integran y discuten. En primer lugar, se realizó un diagnóstico de factores para determinar el estado de competitividad y se empleó el cruce estratégico FODA para definir las estrategias. Seguidamente, se procedió a caracterizar el modelo alineando los servicios del observatorio con las funciones sustantivas. Finalmente, con los resultados se ejemplificó el servicio de asesoramiento empresarial aplicando el ciclo PHVA. Se pudo concluir que el observatorio opto por una propuesta de un modelo basado en acciones estratégicas que permiten generar eficiencia y eficacia de forma continua. Con fecha 4-10-2021 se recibe la carta de validación del modelo con una calificación de excelente.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1673
La solvencia de las MiPymes en la provincia de Tungurahua: un análisis desde la perspectiva de Altman y Ohlson
Authors: Chachipanta Cárdenas Daniela , Córdova Pacheco Ana , Bedoya Jara Mayra , Salazar Mosquera Germán
Published: June 2024

El presente estudio permite analizar las premisas teóricas mediante la comparación de previas investigaciones que influyen al estudio de la predicción de la insolvencia empresarial; a su vez permita evaluar el uso de indicadores financieros obtenidos con la aplicación de los modelos de predicción del fracaso empresarial, determinando si las empresas presentan dificultades financieras mediante la información contenida en los estados financieros. Se obtuvo una muestra de 200 empresas de la provincia de Tungurahua, conformadas por distintos sectores económicos, en el período 2016 – 2019, y con el uso metodológico de cada modelo se puede medir la probabilidad de que una empresa se encuentre en un estado de insolvencia. Finalmente se compararon los modelos de Altman y Ohlson, como herramientas de análisis, mismas que permitieron evaluar las amenazas de estabilidad financiera; estos modelos alcanzaron porcentajes de aciertos muy significativos permitiendo la toma de decisiones pertinentes, evitando el cierre de estas empresas, además se pudo determinar el grado de precisión y de confiabilidad entre los modelos circunda del 70 al 90%.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1797
Análisis del comportamiento del consumidor ante el aumento del impuesto a las bebidas azucaradas en la ciudad de Ambato, Ecuador
Authors: Martínez Mesías Juan , Mayorga Morales Tito , Pérez Briceño Juan , Vega Vinueza Cynthia
Published: June 2024

La finalidad del siguiente estudio es analizar el impacto que tuvo el Impuesto a los Consumos Especiales (ICE) en la venta de bebidas azucaradas en el cantón Ambato, para lo cual como primer punto se describe las preferencias de los consumidores para ello se realizó un análisis de preferencias a través de la descripción del PREFMAP, además se categoriza a los consumidores para establecer su perfil en base a una asociación de un conjunto de variables mediante el Análisis de Componentes Principales (ACP) y la descripción del Bitplot, y finalmente se analiza el consumo ante el incremento del impuesto para lo cual se realiza un análisis inferencial por medio de un test estadístico t de Student. Se identificó una disminución en el consumo de bebidas azucaradas debido al Impuesto de Consumos Especiales (ICE). Esto se determinó al evidenciarse un valor p significativo al 1%, además de que se reconoció que el valor del estadístico t de Student de 6,987 es mayor que el valor crítico de 2,2446, razón por la cual se comprueba la hipótesis alterna.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1798
El Covid 19 y el turismo ecuatoriano, impactos en el sector hotelero
Authors: Albornoz Garzón María , Gómez Romo María , Silva Ajila Diana , López Gómez Andrés
Published: June 2024

La pandemia de Covid-19 ha provocado crisis sanitarias, muertes y el colapso de la economía mundial. Entre los sectores más afectados está el sector turístico. Esta investigación tiene un enfoque cuantitativo, es de tipo longitudinal y de carácter descriptivo - explicativo, cuyo objetivo es proyectar los valores de los principales indicadores del sector hotelero en un escenario con y sin pandemia.  Se utilizó datos obtenidos del Ministerio de Turismo del período comprendido entre el año 2015 al 2020, y 2021 para el feriado de carnaval. El estudio se direccionó a las capitales de las provincias con mayor acogida turística, e incluye también a las capitales de las provincias de la zona 3 del Ecuador por considerarlas destinos de paso para diversas actividades comerciales del centro del país, además de la ciudad de Baños. Se hizo análisis descriptivos para obtener los promedios de los indicadores, mientras que se utilizó las técnicas inferenciales de la regresión lineal simple y de la estimación para hacer las proyecciones de los indicadores. Los resultados de este estudio reflejan un escenario desalentador para el 2020 y 2021 lo que obligaría a las empresas hoteleras a establecer estrategias y planes innovadores que fortalezcan la sostenibilidad financiera.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1849
¿La balanza de pagos limita el crecimiento económico? Nueva evidencia para Chile periodo 1980-2019. El papel de los flujos de capital
Authors: Yunga Medina Fernando , Tapia Morquecho Carlos , Camacho Manzanillas Shaley , Cueva Jiménez Alex
Published: June 2024

Thirlwall (1979) afirmó que el crecimiento económico principalmente de los países en vías de desarrollo está limitado por la balanza de pagos, debido a la dependencia en las exportaciones. El objetivo del presente trabajo fue verificar el crecimiento económico bajo el enfoque de la ley de Thirlwall ampliada a flujos de capital para el caso chileno durante 1980-2019. Los datos se obtuvieron de los indicadores del desarrollo del Banco Mundial (2021). Se aplicó una estrategia econométrica mediante el proceso de un modelo de Vectores Autorregresivos (VAR), causalidad de Granger (1969), cointegración de Engle-Granger (1987) y Johansen (1991), y finalmente se estima un modelo de Corrección de Errores Vectoriales (VEC) para determinar la relación a largo plazo. Los resultados muestran que se cumple la Ley de Thirlwall. Además, al integrar los flujos de capital (IED) el país ha demostrado una relación de largo plazo. Existe una relación bidireccional entre el Producto Interno Bruto (PIB) y las exportaciones, y una relación unidireccional que va desde el PIB hacia la IED. La política económica podría enfocarse en diversificar las exportaciones, y fomentar la entrada de nuevos capitales suavizando los términos normativos internos.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1851
Factores motivacionales para el emprendimiento de negocios de cocina oculta
Authors: Vera Pacheco Dennisse , Segura Ronquillo Shirley
Published: June 2024

La subsistencia económica y satisfacción de necesidades representan factores que a priori podrían motivar a toda persona a emprender un negocio.  Emprender pareciera algo fácil e ingenioso si se tiene una idea de producto innovador que simplifique procesos y costos.  La cocina oculta ha explorado este campo amplio y complejo de hacer negocios y en el presente estudio se identifican los factores que motivan el emprendimiento formal de negocios de cocina oculta.  La metodología aplicada es de corte descriptiva y transversal.  El trabajo de campo consistió en la búsqueda exhaustiva de establecimientos formales de cocina oculta en el sector norte de la ciudad de Guayaquil.  Se identificaron 64 establecimientos legalmente constituidos.  Los hallazgos muestran que las crisis marcan la presencia de estos negocios desarrollados por adultos jóvenes con estudios universitarios y en el segmento de comidas rápidas.  Se determinó que el conocimiento y la experiencia laboral son los factores que motivan a los profesionales a emprender, y los factores menos motivadores, pero no menos importantes, están relacionados con aspectos sociales y de recursos como obtener ingresos económicos altos, un mejor estatus social, invertir sus recursos propios y las políticas públicas de estímulos para el emprendimiento.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1959
Gasto turístico en alimentación y la cocina local del cantón Patate
Authors: Lesano Martínez Vanessa , Monge Martínez Johanna , Almeida Campaña Iván
Published: June 2024

Ecuador es un país con los 4 mundos, lleno de legados y patrimonios culturales inmateriales como lo es la gastronomía, es uno de los principales motores económicos de los destinos turísticos. Los turistas se enriquecen y aprenden de los conocimientos tradicionales de los habitantes mediante la experiencia y trayectoria en el lugar. El objetivo de esta investigación es identificar el gasto turístico en alimentación y difundir a la cocina local del cantón Patate. La metodología utilizada es un enfoque mixto, por lo tanto, se aplicó tres instrumentos, la entrevista, las fichas del atlas alimentario y encuesta. Para la parte cualitativa se realizó en campo a expertos de las distintas características de la cocina local. Por otra parte, se realizó una encuesta a turistas con el fin de conocer el gasto turístico alimentario en el cantón y su motivación de visita. Existe un alto porcentaje de gasto turístico en alimentación y la cocina local de Patate está representada por productos que tienen conexión con la historia del cantón. Como resultados se obtuvo una propuesta apta para personas con discapacidad visual, es una revista hablada que cumple como función adaptarse a todos los visitantes y así conseguir un turismo accesible.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/1961
Procesos participativos en las políticas públicas con enfoque de derechos humanos
Authors: Iturralde Durán Carlos , Duque Romero Lenin
Published: June 2024

El presente artículo tiene el objetivo de reflexionar sobre la importancia de los procesos participativos en las políticas públicas desde la perspectiva de derechos, utilizando la investigación documental y bibliográfica con enfoque cualitativo-descriptivo, y concibiendo a las políticas como intervenciones realizadas por los gobiernos para tratar de cambiar una realidad hacia otra que tenga mayor ejercicio de derechos, y, por ende, que genere mejores niveles de calidad de vida de los agentes beneficiarios. Con tres fases que comprende su ciclo, las políticas públicas tienen una estructura técnica articulada, donde el diseño, la gestión y evaluación se conciben como un solo cuerpo, no obstante, la aplicación fáctica de la evaluación ex post está poco institucionalizada. En cada una de ellas, la generación de procesos participativos potencializa su efectividad, complementando el conocimiento técnico con el saber ciudadano y generando información útil para la toma de decisiones que mejora la eficiencia y eficacia del accionar público, pero también, proporcionando mayor legitimidad y gobernanza a la vez que contribuye con la ampliación de libertades y capacidades de la población, robusteciendo la democracia; no obstante, aún deben desarrollarse mecanismos más apropiados para su aplicación además de una cultura institucional con mayor conciencia de sus beneficios.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/2083
Aplicación de la frontera eficiente de Markowitz en la optimización de portafolios de inversiones
Authors: Molina Panchi Pablo , Molina Panchi Diego , Flores Tapia Carlos
Published: June 2024

El artículo tiene como objetivo aplicar la frontera eficiente de Markowitz en la optimización de portafolios a un caso de estudio empresarial para la selección óptima de la cartera de inversión con la máxima rentabilidad y el mínimo riesgo. A partir de la teoría del portafolio de Markowitz y con el uso de técnicas estadísticas como Kolmogórov-Smirnov, correlación de Pearson y modelos matemáticos ARIMA de metodología Jenkins-Box se procesan y analizan los rendimientos esperados de los activos financieros de dos empresas que cotizan en el mercado de valores ecuatoriano y forman parte del indicador bursátil Ecuindex y el caso de una empresa que cotiza en el mercado de valores de Brasil. El enfoque del estudio es cuantitativo y tiene un alcance explicativo-correlacional, puesto que se pretende explicar el posible comportamiento de la esperanza matemática y el grado de relación de sus variables, así como evaluar el ciclo histórico de los años 2017 al 2021 y establecer predicciones de dichos comportamientos. Los principales resultados muestran que, por una parte, la diversificación funciona con el riesgo no sistemático porque los activos financieros no poseen una correlación perfecta y, por otra, el cálculo de la frontera eficiente y modelo de valoración de activos de capital permite seleccionar la mejor opción de rentabilidad-riesgo, contribuyendo a la toma de decisiones.
URL: https://revistas.uta.edu.ec/erevista/index.php/bcoyu/article/view/2084
LGI 1 Antibody Encephaltis:Clinical characteristics and short term outcome along with review of literature.
Authors: Panicker Praveen , Ramachandran Dileep , Chandran Raj Satheesh , Iype Thomas
Published: June 2024

LGI1 (Leucine-rich glioma inactivated protein-1) antibody disease is one of the major causes of limbic encephalitis encountered in clinical practice manifesting with clinical seizures, behavioural disturbances and movement disorders. Here we discuss the varied presentations of this disease through three cases encountered at our center emphasizing the cardinal clinical, imaging and laboratory diagnostic features. Recognition of these characteristics would lead to early diagnosis and prompt management of this eminently treatable condition.