bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 3 from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 32K, Association of selected polymorphisms with CRC clinical characteristics.
Supplementary Figure 3 from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 66K, Supplementary Figure 3. IFN-gammaR-/- mice are resistant to the growth of transplanted lymphoma due to high levels of serum IFN-gamma.
Supplementary Figure 1 from An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
Authors: West Alison C. , Mattarollo Stephen R. , Shortt Jake , Cluse Leonie A. , Christiansen Ailsa J. , Smyth Mark J. , Johnstone Ricky W.
Published: March 2023

PDF file - 25K, Supplementary Figure 1. Vorinostat treatment of MC38 cells induces hallmarks of immunogenic cell death.
Supplementary Methods from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 182K
Supplementary Figure Legend from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 107K
Supplementary Figure 3 from Functional TLR5 Genetic Variants Affect Human Colorectal Cancer Survival
Authors: Klimosch Sascha N. , Försti Asta , Eckert Jana , Knežević Jelena , Bevier Melanie , von Schönfels Witigo , Heits Nils , Walter Jessica , Hinz Sebastian , Lascorz Jesus , Hampe Jochen , Hartl Dominik , Frick Julia-Stefanie , Hemminki Kari , Schafmayer Clemens , Weber Alexander N.R.
Published: March 2023

PDF file - 143K, Work flow for analyses in whole blood.
Supplementary Figure Legends from Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer
Authors: Balko Justin M. , Schwarz Luis J. , Bhola Neil E. , Kurupi Richard , Owens Phillip , Miller Todd W. , Gómez Henry , Cook Rebecca S. , Arteaga Carlos L.
Published: March 2023

PDF file, 77K.
Supplementary Tables 1 - 3 from Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases
Authors: Zhao Hong , Jin Guangxu , Cui Kemi , Ren Ding , Liu Timothy , Chen Peikai , Wong Solomon , Li Fuhai , Fan Yubo , Rodriguez Angel , Chang Jenny , Wong Stephen TC
Published: March 2023

PDF file - 43K, Enriched signaling pathways for the differentially expressed genes in brain, lung and bone metastasis (S1); Repositioned drug candidates for lung metastasis of breast cancer (S2); Expression of p-RET and p-FYN in brain metastases tissues of breast cancer patient (S3).
Supplementary Figures 1 - 7 from Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases
Authors: Zhao Hong , Jin Guangxu , Cui Kemi , Ren Ding , Liu Timothy , Chen Peikai , Wong Solomon , Li Fuhai , Fan Yubo , Rodriguez Angel , Chang Jenny , Wong Stephen TC
Published: March 2023

PDF file - 1060K, CCSB derived signaling networks for distinct breast cancer metastases (S1); Chemical structures of the candidate repositioned drugs and their parameters for the "Rule of Five." (S2); Western Immunoblot analysis of RET, FYN and the down-stream pathway proteins in indicated cell lines (S3); Relationship between the brain metastasis core signaling network and ER, PR, HER2 status in different breast tumor cohorts (S4); Evaluation of p-FYN and p-RET activation and tumor loci surrounding edema and vessels in the brain metastatis mouse models (S5); Pharmacokinetic study of Sunitinib and Dasatinib accumulated in brain of the xenograft models (S6); The three-dimensional cubes for the best subtrees in the survival analysis (S7).
Supplementary Figure S7 from Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity
Authors: Kwong Brandon , Gai S. Annie , Elkhader Jamal , Wittrup K. Dane , Irvine Darrell J.
Published: March 2023

upplementary Figure S7 PDF file 43K, NK cell infiltration in treated and distal tumors following Lip-�CD137 + Lip-IL-2Fc therapy
Supplementary Legends for Tables 1-4 and Figures 1-7 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

PDF file - 64K
Supplementary Figures 1-4 from Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
Authors: Tyner Jeffrey W. , Yang Wayne F. , Bankhead Armand , Fan Guang , Fletcher Luke B. , Bryant Jade , Glover Jason M. , Chang Bill H. , Spurgeon Stephen E. , Fleming William H. , Kovacsovics Tibor , Gotlib Jason R. , Oh Stephen T. , Deininger Michael W. , Zwaan Christian Michel , Den Boer Monique L. , van den Heuvel-Eibrink Marry M. , O'Hare Thomas , Druker Brian J. , Loriaux Marc M.
Published: March 2023

PDF file - 2.3MB, (S1) Scheme for profiling leukemia patient samples with a panel of kinase inhibitors; (S2) Rank ordering of 151 sample IC50 values for each small-molecule kinase inhibitor; (S3) One-way clustering of leukemia patient sample response to small-molecule kinase inhibitors; (S4) Two-way clustering of leukemia patient sample response to small-molecule kinase inhibitors
Supplementary Figure 7 from Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met–driven Pancreatic Carcinoma
Authors: Avan Amir , Caretti Viola , Funel Niccola , Galvani Elena , Maftouh Mina , Honeywell Richard J. , Lagerweij Tonny , Van Tellingen Olaf , Campani Daniela , Fuchs Dieter , Verheul Henk M. , Schuurhuis Gerrit-Jan , Boggi Ugo , Peters Godefridus J. , Würdinger Thomas , Giovannetti Elisa
Published: March 2023

PDF file - 55K, Correlation between BLI data and volumes detected at high frequency ultrasound.
Supplementary Table 4 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
Authors: Jansen Maurice P.H.M. , Knijnenburg Theo , Reijm Esther A. , Simon Iris , Kerkhoven Ron , Droog Marjolein , Velds Arno , van Laere Steven , Dirix Luc , Alexi Xanthippi , Foekens John A. , Wessels Lodewyk , Linn Sabine C. , Berns Els M.J.J. , Zwart Wilbert
Published: March 2023

PDF file - 129K, Supplementary Table S4 Differential bound regions for ERalpha, H3K4me3 or H3K27me3 in 'poor' and 'good' outcome patients.
Supplementary Figure 4 from Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met–driven Pancreatic Carcinoma
Authors: Avan Amir , Caretti Viola , Funel Niccola , Galvani Elena , Maftouh Mina , Honeywell Richard J. , Lagerweij Tonny , Van Tellingen Olaf , Campani Daniela , Fuchs Dieter , Verheul Henk M. , Schuurhuis Gerrit-Jan , Boggi Ugo , Peters Godefridus J. , Würdinger Thomas , Giovannetti Elisa
Published: March 2023

PDF file - 1445K, Genetic characterization of the PDAC-FM-GC mouse models.
Supplementary Figure 1 from Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met–driven Pancreatic Carcinoma
Authors: Avan Amir , Caretti Viola , Funel Niccola , Galvani Elena , Maftouh Mina , Honeywell Richard J. , Lagerweij Tonny , Van Tellingen Olaf , Campani Daniela , Fuchs Dieter , Verheul Henk M. , Schuurhuis Gerrit-Jan , Boggi Ugo , Peters Godefridus J. , Würdinger Thomas , Giovannetti Elisa
Published: March 2023

PDF file - 353K, BLI quantification of tumor growth and survival analysis in PDAC-1/2/3/4-FM-GC mouse models.
Supplementary Figure 6 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
Authors: Jansen Maurice P.H.M. , Knijnenburg Theo , Reijm Esther A. , Simon Iris , Kerkhoven Ron , Droog Marjolein , Velds Arno , van Laere Steven , Dirix Luc , Alexi Xanthippi , Foekens John A. , Wessels Lodewyk , Linn Sabine C. , Berns Els M.J.J. , Zwart Wilbert
Published: March 2023

PDF file - 198K, Supplementary Figure S6 Differential response to aromatase inhibitors, using ChiA-PET associated genes and genes overlapping between proximity and ChIA-PET data.
Supplementary Figure 3 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
Authors: Jansen Maurice P.H.M. , Knijnenburg Theo , Reijm Esther A. , Simon Iris , Kerkhoven Ron , Droog Marjolein , Velds Arno , van Laere Steven , Dirix Luc , Alexi Xanthippi , Foekens John A. , Wessels Lodewyk , Linn Sabine C. , Berns Els M.J.J. , Zwart Wilbert
Published: March 2023

PDF file - 110K, Supplementary Figure S3 Principal Component Analysis for all three ChIP-seq conditions.
Supplementary Figure 4 from VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis
Authors: Alitalo Annamari K. , Proulx Steven T. , Karaman Sinem , Aebischer David , Martino Stefania , Jost Manuela , Schneider Nicole , Bry Maija , Detmar Michael
Published: March 2023

PDF - 263K, Macrophage polarization.
Supplementary Figure 2 from VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis
Authors: Alitalo Annamari K. , Proulx Steven T. , Karaman Sinem , Aebischer David , Martino Stefania , Jost Manuela , Schneider Nicole , Bry Maija , Detmar Michael
Published: March 2023

PDF - 1798K, Blood leukocyte and monocyte counts.
Supplementary Figure 6 from Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin
Authors: Cao Ying , Hoeppner Luke H. , Bach Steven , E Guangqi , Guo Yan , Wang Enfeng , Wu Jianmin , Cowley Mark J. , Chang David K. , Waddell Nicola , Grimmond Sean M. , Biankin Andrew V. , Daly Roger J. , Zhang Xiaohui , Mukhopadhyay Debabrata
Published: March 2023

PDF file - 59K, Supplemental Fig.6. NRP-2 did not co-immunoprecipitate with Integrin a2, a3, a6 or aV.
Supplementary Figure 4 from Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin
Authors: Cao Ying , Hoeppner Luke H. , Bach Steven , E Guangqi , Guo Yan , Wang Enfeng , Wu Jianmin , Cowley Mark J. , Chang David K. , Waddell Nicola , Grimmond Sean M. , Biankin Andrew V. , Daly Roger J. , Zhang Xiaohui , Mukhopadhyay Debabrata
Published: March 2023

PDF file - 86K, Supplemental Fig.4. (A). NRP-2 levels in 786-O cells after overexpression or knockdown. (B). NRP-2 overexpression or knockdown didn't significantly change the abilities to adhere to blank plate and Collagen I coated plate.
Supplementary Figure 1 from Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence
Authors: Angelini Pier Davide , Fluck Mariano F. Zacarias , Pedersen Kim , Parra-Palau Josep Lluís , Guiu Marc , Bernadó Morales Cristina , Vicario Rocio , Luque-García Antonio , Navalpotro Nerea Peiró , Giralt Jordi , Canals Francesc , Gomis Roger R. , Tabernero Josep , Baselga José , Villanueva Josep , Arribas Joaquín
Published: March 2023

PDF file - 104K, Expression of p95HER2 in MCF10A, T47D and MDA-MB-453 cells and expression of HER2 in MCF7 cells
Supplementary Figure 2 from Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin
Authors: Cao Ying , Hoeppner Luke H. , Bach Steven , E Guangqi , Guo Yan , Wang Enfeng , Wu Jianmin , Cowley Mark J. , Chang David K. , Waddell Nicola , Grimmond Sean M. , Biankin Andrew V. , Daly Roger J. , Zhang Xiaohui , Mukhopadhyay Debabrata
Published: March 2023

PDF file - 239K, Supplemental Fig.2. NRP-2 knockdown in 786-O cells didn't significantly change the blood vessels and lymphatic vessels densities in the primary tumors. (A). Representative images of vWF stained blood vessels. (B). Quantification of vWF staining. One typical area from the edge of the tumor (to avoid the necrotic area) was taken and vWF vessel density was quantified. n=5. (C). Representative images of LYVE stained lymphatic vessels. (D). Quantification of LYVE staining. One typical area from the edge of the tumor (to avoid the necrotic area) was taken and LYVE vessel density was quantified. n=5.
Supplementary Figure 1 from Nkx2-8 Downregulation Promotes Angiogenesis and Activates NF-κB in Esophageal Cancer
Authors: Lin Chuyong , Song Libing , Gong Hui , Liu Aibin , Lin Xi , Wu Jueheng , Li Mengfeng , Li Jun
Published: March 2023

PDF file - 32K, Western blotting analysis of Nkx2-8 expression in Kyse30 (A) and Kyse510 (B) ESCC cells stably expressing Nkx2-8-cDNA and Nkx2-8-shRNA(s).
Supplementary Figure 1 from miR145 Targets the SOX9/ADAM17 Axis to Inhibit Tumor-Initiating Cells and IL-6–Mediated Paracrine Effects in Head and Neck Cancer
Authors: Yu Cheng-Chia , Tsai Lo-Lin , Wang Mong-Lien , Yu Chuan-Hang , Lo Wen-Liang , Chang Yun-Ching , Chiou Guang-Yuh , Chou Ming-Yung , Chiou Shih-Hwa
Published: March 2023

PDF file - 235K, Suppl. Fig 1. Clustering the progressive miRNA and mRNA expression profiles of in HNC-TICs
Supplementary Materials and Methods from TR3 Modulates Platinum Resistance in Ovarian Cancer
Authors: Wilson Andrew J. , Liu Annie Y. , Roland Joseph , Adebayo Oluwafunmilayo B. , Fletcher Sarah A. , Slaughter James C. , Saskowski Jeanette , Crispens Marta A. , Jones Howard W. , James Samuel , Fadare Oluwole , Khabele Dineo
Published: March 2023

PDF - 80K, Additional details about methodology used for Immunofluorescence, Immunohistochemistry, Western Blotting, quantitative RT-PCR and case selection and TMA generation.
Supplementary Figure 3 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: March 2023

PDF file - 136K, iNOS/NO downregulated DKK1 gene expression in cancer cells. A, HCT116 and MCF7 cell lines were treated with NO donor SNAP (500 microM) for 4 hrs. Total RNA was isolated for RT-PCR analysis. B, SW480-DKK1 and SW480-vector (control) cell lines were incubated for 24 hrs and total proteins were isolated for Western blot analysis with the indicated antibodies. C, SW480-DKK1 and SW480-vector cell lines were transfected with pTOP/pFOP for 48 hrs, and the cell lysates were used for luciferase reporter assay. D, SW480-iNOS-DKK1and SW480-iNOS-vector cell lines were incubated for 24 hours. Total proteins were collected for Western blot analysis with iNOS and DKK1 antibodies. E, HCT116 cells were transfected with pCDNA3-hiNOS and pCDNA3-vector, and with pcDNA3.1/V5-His-hDDK1 and pCDNA3.1/V5-His-vector. After 36 hours, total protein was isolated for immunoblotting with c-MYC or Beta-actin antibody.
Supplementary Table 2 from A Classification Model for BRCA2 DNA Binding Domain Missense Variants Based on Homology-Directed Repair Activity
Authors: Guidugli Lucia , Pankratz Vernon S. , Singh Namit , Thompson James , Erding Catherine A. , Engel Christoph , Schmutzler Rita , Domchek Susan , Nathanson Katherine , Radice Paolo , Singer Christian , Tonin Patricia N. , Lindor Noralane M. , Goldgar David E. , Couch Fergus J.
Published: March 2023

PDF file - 58K, Table showing model-based estimates of conditional probabilities in favor or against pathogenicity for VUS based on HDR activity calculated with equal prior probabilities or AGVGD-based prior probabilities for each variant
Supplementary Table 1 from A Classification Model for BRCA2 DNA Binding Domain Missense Variants Based on Homology-Directed Repair Activity
Authors: Guidugli Lucia , Pankratz Vernon S. , Singh Namit , Thompson James , Erding Catherine A. , Engel Christoph , Schmutzler Rita , Domchek Susan , Nathanson Katherine , Radice Paolo , Singer Christian , Tonin Patricia N. , Lindor Noralane M. , Goldgar David E. , Couch Fergus J.
Published: March 2023

PDF file - 66K, Table showing the normalized mean HDR assay fold-change and log transformed values for each VUS
Supplementary Figure 2 from miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma, Where It Interferes with Cell-Cycle Regulation
Authors: Cai Junchao , Wu Jueheng , Zhang Huizhong , Fang Lishan , Huang Yongbo , Yang Yi , Zhu Xun , Li Rong , Li Mengfeng
Published: March 2023

PDF file - 24K, Real-time analysis of miR-186 expression in A549 and SK-MES-1 cells transfected with anti-miR-186 (Anti-miR) or NC oligonucleotides
Supplementary Table 5 from ALDH1-Positive Cancer Stem Cells Predict Engraftment of Primary Breast Tumors and Are Governed by a Common Stem Cell Program
Authors: Charafe-Jauffret Emmanuelle , Ginestier Christophe , Bertucci François , Cabaud Olivier , Wicinski Julien , Finetti Pascal , Josselin Emmanuelle , Adelaide José , Nguyen Tien-Tuan , Monville Florence , Jacquemier Jocelyne , Thomassin-Piana Jeanne , Pinna Guillaume , Jalaguier Aurélie , Lambaudie Eric , Houvenaeghel Gilles , Xerri Luc , Harel-Bellan Annick , Chaffanet Max , Viens Patrice , Birnbaum Daniel
Published: March 2023

Table SV. Public datasets description utilised for the BCSC-GES study
Supplementary Figure 2 from ANTXR1, a Stem Cell-Enriched Functional Biomarker, Connects Collagen Signaling to Cancer Stem-like Cells and Metastasis in Breast Cancer
Authors: Chen Daohong , Bhat-Nakshatri Poornima , Goswami Chirayu , Badve Sunil , Nakshatri Harikrishna
Published: March 2023

PDF file, 8586K, Ingenuity pathway analysis of differentially expressed genes in ANTXR1 knockdown cells.
Supplementary Methods from Breast Tumor Kinase (Brk/PTK6) Is a Mediator of Hypoxia-Associated Breast Cancer Progression
Authors: Regan Anderson Tarah M. , Peacock Danielle L. , Daniel Andrea R. , Hubbard Gregory K. , Lofgren Kristopher A. , Girard Brian J. , Schörg Alexandra , Hoogewijs David , Wenger Roland H. , Seagroves Tiffany N. , Lange Carol A.
Published: March 2023

PDF file, 100K.
Supplementary Figure 3 from Breast Tumor Kinase (Brk/PTK6) Is a Mediator of Hypoxia-Associated Breast Cancer Progression
Authors: Regan Anderson Tarah M. , Peacock Danielle L. , Daniel Andrea R. , Hubbard Gregory K. , Lofgren Kristopher A. , Girard Brian J. , Schörg Alexandra , Hoogewijs David , Wenger Roland H. , Seagroves Tiffany N. , Lange Carol A.
Published: March 2023

PDF file, 2022K, Western and mRNA data downing retroviral transduction of Brk gene and subsequent over expression, as well as maintenance of HIF1a/2a knockdown.
Supplementary Table 1 from A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells
Authors: Gallo Marco , Ho Jenny , Coutinho Fiona J. , Vanner Robert , Lee Lilian , Head Renee , Ling Erick K. M. , Clarke Ian D. , Dirks Peter B.
Published: March 2023

PDF file - 2.6MB, Glioma characteristics
Supplementary Figure 2 from Resistance to Irreversible EGF Receptor Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway
Authors: Cortot Alexis B. , Repellin Claire E. , Shimamura Takeshi , Capelletti Marzia , Zejnullahu Kreshnik , Ercan Dalia , Christensen James G. , Wong Kwok-Kin , Gray Nathanael S. , Jänne Pasi A.
Published: March 2023

PDF file - 158K, IGF1R inhibition alone does not effect growth of PFR or WZR cells
Supplementary Figure 10 from A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells
Authors: Gallo Marco , Ho Jenny , Coutinho Fiona J. , Vanner Robert , Lee Lilian , Head Renee , Ling Erick K. M. , Clarke Ian D. , Dirks Peter B.
Published: March 2023

PDF file - 43K, Significantly up-regulated genes in Group 2 vs. Group 1 primary patient tumor samples
Supplementary Methods from Connective Tissue Growth Factor Activates Pluripotency Genes and Mesenchymal–Epithelial Transition in Head and Neck Cancer Cells
Authors: Chang Cheng-Chi , Hsu Wen-Hao , Wang Chen-Chien , Chou Chun-Hung , Kuo Mark Yen-Ping , Lin Been-Ren , Chen Szu-Ta , Tai Shyh-Kuan , Kuo Min-Liang , Yang Muh-Hwa
Published: March 2023

PDF file - 93K, The Supplemental Methods file includes additional information regarding Sample Collection and analysis, Reverse Transcription and Quantitative PCR analysis, Western Blot and Flow Cytometry analysis, Immunohistochemistry data, and Immunofluorescent staining.
Supplementary Methods from Microtubule-Associated Histone Deacetylase 6 Supports the Calcium Store Sensor STIM1 in Mediating Malignant Cell Behaviors
Authors: Chen Ying-Ting , Chen Yih-Fung , Chiu Wen-Tai , Liu Kuan-Yu , Liu Yu-Lin , Chang Jang-Yang , Chang Hsien-Chang , Shen Meng-Ru
Published: March 2023

PDF file - 155K, Additional experimental procedures including RNA interference, Total internal reflection fluorescence (TIRF) microscopy, and cell proliferation and migration assay. Also includes description of antibodies and reagents used.
Supplementary Figure S4 from Integration of High-Resolution Methylome and Transcriptome Analyses to Dissect Epigenomic Changes in Childhood Acute Lymphoblastic Leukemia
Authors: Busche Stephan , Ge Bing , Vidal Ramon , Spinella Jean-François , Saillour Virginie , Richer Chantal , Healy Jasmine , Chen Shu-Huang , Droit Arnaud , Sinnett Daniel , Pastinen Tomi
Published: March 2023

PDF - 223K, Correlation of DNA methylation and gene expression
Supplementary Figure 2 from Microtubule-Associated Histone Deacetylase 6 Supports the Calcium Store Sensor STIM1 in Mediating Malignant Cell Behaviors
Authors: Chen Ying-Ting , Chen Yih-Fung , Chiu Wen-Tai , Liu Kuan-Yu , Liu Yu-Lin , Chang Jang-Yang , Chang Hsien-Chang , Shen Meng-Ru
Published: March 2023

PDF file - 732K, HDAC6 and a-tubulin deacetylation in cervical cancer cells.
Supplementary Figure 2 from miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1
Authors: Huang Xiaoyong , Taeb Samira , Jahangiri Sahar , Emmenegger Urban , Tran Elisa , Bruce Jeff , Mesci Aruz , Korpela Elina , Vesprini Danny , Wong C. Shun , Bristow Robert G. , Liu Fei-Fei , Liu Stanley K.
Published: March 2023

PDF file - 9492K, Characterization of DU145 cells transfected with miR-95 mimic.
Supplementary Figure 4 from Gankyrin Activates IL-8 to Promote Hepatic Metastasis of Colorectal Cancer
Authors: Bai Zhaofang , Tai Yanhong , Li Weihua , Zhen Cheng , Gu Weiting , Jian Zhao , Wang Qianyi , Lin Jieru E. , Zhao Qing , Gong Weili , Liang Bing , Wang Chenguang , Zhou Tao
Published: March 2023

PDF file - 82K, Confirmation of altered gene expression in a subset of genes regulated by Gankyrin in microarray analysis.
Supplementary Tables 1 - 2 from Optical Metabolic Imaging Identifies Glycolytic Levels, Subtypes, and Early-Treatment Response in Breast Cancer
Authors: Walsh Alex J. , Cook Rebecca S. , Manning H. Charles , Hicks Donna J. , Lafontant Alec , Arteaga Carlos L. , Skala Melissa C.
Published: March 2023

PDF file - 198K, Breast cancer cell lines and receptor expression (S1); Correlations among optical metabolic measurements (S2).
Supplementary Table 3 from G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic
Authors: Hsu Danielle M. , Agarwal Saurabh , Benham Ashley , Coarfa Cristian , Trahan Denae N. , Chen Zaowen , Stowers Paris N. , Courtney Amy N. , Lakoma Anna , Barbieri Eveline , Metelitsa Leonid S. , Gunaratne Preethi , Kim Eugene S. , Shohet Jason M.
Published: March 2023

PDF file - 52K, MicroRNA expression defined by small-RNA sequencing in three neuroblastoma cell lines.
Supplementary Table S1 from Alkaline Phosphatase ALPPL-2 Is a Novel Pancreatic Carcinoma-Associated Protein
Authors: Dua Pooja , Kang Hye Suk , Hong Seung-Mo , Tsao Ming-Sound , Kim Soyoun , Lee Dong-ki
Published: March 2023

Supplementary Table S1 PDF file - 351K, Table S1 List of top 10 differentially expressed genes in Panc-1+ve cells relative to Panc-1-ve cells
Supplementary Figure 5 from Novel Small-Molecule Inhibitors of Bcl-XL to Treat Lung Cancer
Authors: Park Dongkyoo , Magis Andrew T. , Li Rui , Owonikoko Taofeek K. , Sica Gabriel L. , Sun Shi-Yong , Ramalingam Suresh S. , Khuri Fadlo R. , Curran Walter J. , Deng Xingming
Published: March 2023

PDF file, 73K, Irradiation resistance (IRR) is associated with elevated levels of Bcl-XL and Bcl-2 in human lung cancer cells.
Supplementary Figure 2 from Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells
Authors: Khanna Anchit , Kauko Otto , Böckelman Camilla , Laine Anni , Schreck Ilona , Partanen Johanna I. , Szwajda Agnieszka , Bormann Stefanie , Bilgen Turker , Helenius Merja , Pokharel Yuba R. , Pimanda John , Russel Mike R. , Haglund Caj , Cole Kristina A. , Klefström Juha , Aittokallio Tero , Weiss Carsten , Ristimäki Ari , Visakorpi Tapio , Westermarck Jukka
Published: March 2023

PDF file - 85K, Figure S2. Chk1 and Claspin (CLSPN) positively regulate CIP2A protein expression in human cancer cells.
Supplementary Figure Legend from YEATS4 Is a Novel Oncogene Amplified in Non–Small Cell Lung Cancer That Regulates the p53 Pathway
Authors: Pikor Larissa A. , Lockwood William W. , Thu Kelsie L. , Vucic Emily A. , Chari Raj , Gazdar Adi F. , Lam Stephen , Lam Wan L.
Published: March 2023

PDF file - 103K
Supplementary Methods, Tables 1 - 3, Figures 1 - 4 from ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton
Authors: Yuan Xiangliang , Yu Liang , Li Junhua , Xie Guohua , Rong Tingting , Zhang Liang , Chen Jianhua , Meng Qiaohong , Irving Aaron T. , Wang Die , Williams Elizabeth D. , Liu Jun-Ping , Sadler Anthony J. , Williams Bryan R.G. , Shen Lisong , Xu Dakang
Published: March 2023

PDF file - 752K, Table S1. ATF3 expression and clinicopathological findings in bladder cancer. Table S2. Relationship between ATF3 and GSN expression in bladder cancer. Table S3. Multivariate Cox proportional hazards regression for metastasis-free survival of patients with bladder cancer. Figure S1. Establishment and characterization of the highly metastatic cell subline T24-L. Figure S2. Agreement between pathologists and automated staining categories. Figure S3. ATF3 is downregulated in bladder cancer tissue. Figure S4. ATF3 regulates GSN expression in bladder cancer cells.
Supplementary Figures 1-11 from High-Avidity T Cells Are Preferentially Tolerized in the Tumor Microenvironment
Authors: Zhu Ziqiang , Singh Vinod , Watkins Stephanie K. , Bronte Vincenzo , Shoe Jennifer L. , Feigenbaum Lionel , Hurwitz Arthur A.
Published: March 2023

PDF file-439KB, Supplementary Figure S1: Functional avidity of T cell clones 37 vs 24.Supplementary Figure S2: T cells infiltrate the skin of TCRhi mice.Supplementary Figure S3: TCRhi T cells displayed higher functional avidity than TCRlo T cells. Supplementary Figure S4: TCRhi T cells display higher antitumor activity than TCRlo T cells. Supplementary Figure S5: TCRhi not TCRlo T cells infiltrating subcutaneous B16 tumors TCR , TCR become tolerized. Supplementary Figure S6: MHC-I expression on tumor cells was up-regulated after transfer of TCR Tg T cells. Supplementary Figure S7: PD-1 blockade prevent TcRhi tolerization. Supplementary Figure S8: TADCs isolated from B16 tumor express CD11c+/B220+/BST2 (CD317)+. Supplementary Figure S9: Foxo3-/- B16 TADCs do not tolerize TCRhi T cells in vitro. Supplementary Figure S10: Depletion of TADCs with anti-CD317 Ab in subcutaneous B16 tumor. Supplementary Figure S11: Administration of anti-CD317 alone does not alter B16 tumor growth.
Supplementary Figures from Tumor Microenvironmental Conversion of Natural Killer Cells into Myeloid-Derived Suppressor Cells
Authors: Park Young-Jun , Song Boyeong , Kim Yun-Sun , Kim Eun-Kyung , Lee Jung-Mi , Lee Ga-Eun , Kim Jae-Ouk , Kim Yeon-Jeong , Chang Woo-Sung , Kang Chang-Yuil
Published: March 2023

PDF file, 1963K, Inverse relationship between the percentage of Ly6Cneg/low cells and MDSCs (S1); Ly6Cneg/low cells are converted into MDSCs (S2); Only tumor CD49b+ cells, not CD4+ or CD8+ T cells or B cells, are converted into MDSCs (S3); 4 populations of conventional NK cells divided by maturation state (S4); The efficiency of conversion is increased in CD11bhighCD27high NKp46+ cells compared to NKp46+ total cells (S5); Endogenous MDSCs have no impact on NK cell death during the maturation course (S6).
Supplementary Figure Legend from MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Azab Belal , Kegelman Timothy P. , Peachy Leyla , Santhekadur Prasanna K. , Dasgupta Santanu , Dash Rupesh , Dent Paul , Grant Steven , Emdad Luni , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 93K
Supplementary Figure 1 from Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype
Authors: Ying Zhe , Li Yun , Wu Jueheng , Zhu Xun , Yang Yi , Tian Han , Li Wei , Hu Bo , Cheng Shi-Yuan , Li Mengfeng
Published: March 2023

PDF file - 47K, Expression of miR-204 in cell lines stable expresses miR-204 was compared with the expression of miR-204 in normal human astrocyte (NHA).
Supplementary Figure 2 from MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Azab Belal , Kegelman Timothy P. , Peachy Leyla , Santhekadur Prasanna K. , Dasgupta Santanu , Dash Rupesh , Dent Paul , Grant Steven , Emdad Luni , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 89K, Graphical presentation of CD-31 expression in tumor sections.
Supplementary Figures 1 - 5 from Bispecific Antibody to ErbB2 Overcomes Trastuzumab Resistance through Comprehensive Blockade of ErbB2 Heterodimerization
Authors: Li Bohua , Meng Yanchun , Zheng Lei , Zhang Xunmin , Tong Qing , Tan Wenlong , Hu Shi , Li Hui , Chen Yang , Song Jinjing , Zhang Ge , Zhao Lei , Zhang Dapeng , Hou Sheng , Qian Weizhu , Guo Yajun
Published: March 2023

PDF file - 362K, Competitive binding assay (S1); TPL inhibits ErbB2 signaling in breast cancer cell lines (S2); ErbB2 knockdown inhibits ErbB2 signaling and results in growth inhibition in the MDA-MB-231 cell line (S3); TPL inhibited MDA-MB-231 breast cancer cell growth in a dose-dependent manner both in vitro and in vivo (S4); The effects of siRNA knockdown of EGFR or ErbB3 on the BT-474TraR cell line (S5).
Table S2 from Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8
Authors: Hartman Zachary C. , Poage Graham M. , den Hollander Petra , Tsimelzon Anna , Hill Jamal , Panupinthu Nattapon , Zhang Yun , Mazumdar Abhijit , Hilsenbeck Susan G. , Mills Gordon B. , Brown Powel H.
Published: March 2023

Table S2 - XLSX file 77K, Verification of lentiviral shRNA knock-down in SUM159 cells by quantitative RT-PCR
Supplementary Figure 5 from Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Authors: Chakrabarty Anindita , Bhola Neil E. , Sutton Cammie , Ghosh Ritwik , Kuba María Gabriela , Dave Bhuvanesh , Chang Jenny C. , Arteaga Carlos L.
Published: March 2023

PDF file - 162K, Inhibition of survivin and IL8 expression by short-term treatment with XL147 + trastuzumab in HCC1954 xenografts
Supplementary Figure 4 from Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Authors: Chakrabarty Anindita , Bhola Neil E. , Sutton Cammie , Ghosh Ritwik , Kuba María Gabriela , Dave Bhuvanesh , Chang Jenny C. , Arteaga Carlos L.
Published: March 2023

PDF file - 135K, Inhibition of trastuzumab-resistant cells by RNAi or pharmacological inhibition of survivin
Supplementary Figure 6 from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 65K, Supplementary Figure 6. A schematic drawing of full length N1ICD in mouse, N1ICD allele analyzed in this study, and the ACTB-Notch1 allele previously published (Yang et al., 2004) and analyzed in Supplementary Figure 6.
Supplementary Figure 3 from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 133K, Supplementary Figure 3. Reduced p53 dose rescues precocious GFAP expression in the N1ICD;hGFAP-cre brains.
Supplementary Table from miR-205 Targets PTEN and PHLPP2 to Augment AKT Signaling and Drive Malignant Phenotypes in Non–Small Cell Lung Cancer
Authors: Cai Junchao , Fang Lishan , Huang Yongbo , Li Rong , Yuan Jie , Yang Yi , Zhu Xun , Chen Baixue , Wu Jueheng , Li Mengfeng
Published: March 2023

PDF file, 61K, Clinicopathologic characteristics of 60 cases of NSCLC patients.
Supplementary Figure 2 from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 84K, Supplementary Figure 2. Reduced p53 dose rescues brain sizes in N1ICD;hGFAP-cre transgenic mice.
Supplementary Figure 1 from Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Authors: Natarajan Sivaraman , Li Yaochen , Miller Emily E. , Shih David J. , Taylor Michael D. , Stearns Timothy M. , Bronson Roderick T. , Ackerman Susan L. , Yoon Jeong K. , Yun Kyuson
Published: March 2023

PDF file - 158K, Supplementary Figure 1. Reduced p53 dose rescues apoptosis in N1ICD;hGFAP-cre brains.
Supplementary Figures 1-8 from Specific Elimination of CD133+ Tumor Cells with Targeted Oncolytic Measles Virus
Authors: Bach Patricia , Abel Tobias , Hoffmann Christopher , Gal Zoltan , Braun Gundula , Voelker Iris , Ball Claudia R. , Johnston Ian C.D. , Lauer Ulrich M. , Herold-Mende Christel , Mühlebach Michael D. , Glimm Hanno , Buchholz Christian J.
Published: March 2023

PDF file - 734K, S Figure 1 - CD133 and CD46 expression on cell lines. S Figure 2 - CD133 surface expression of HT1080-CD133 and HT1080-RFP cells. S Figure 3 - Monitoring of CD133-levels of virus infected primary colon carcinoma tumor spheres. S Figure 4 - CD133-levels of explanted secondary tumors shown in Fig. 3D. S Figure 5 - CD133-levels of infected glioma tumor spheres. S Figure 6 - Analysis of multi-focal HuH7-luc tumor model. S Figure 7- Oncolytic activity of MV-141.7 in a multi-focal HuH7 tumor model. S Figure 8 - Necropsy of a long-term survivor mouse showing a weak luciferase tumor cell signal
Supplementary Table 2 from Autoantibody Signatures Involving Glycolysis and Splicesome Proteins Precede a Diagnosis of Breast Cancer among Postmenopausal Women
Authors: Ladd Jon J. , Chao Timothy , Johnson Melissa M. , Qiu Ji , Chin Alice , Israel Rebecca , Pitteri Sharon J. , Mao Jianning , Wu Mei , Amon Lynn M. , McIntosh Martin , Li Christopher , Prentice Ross , Disis Nora , Hanash Samir
Published: March 2023

PDF file - 48K, Peptide sequences from proteins identified in immune complexes.
Supplementary Figures 1 - 8, Tables 1 - 3 from NF-κB Gene Signature Predicts Prostate Cancer Progression
Authors: Jin Renjie , Yi Yajun , Yull Fiona E. , Blackwell Timothy S. , Clark Peter E. , Koyama Tatsuki , Smith Joseph A. , Matusik Robert J.
Published: March 2023

PDF file - 453KB, Supplementary Figure 1. NF-kappaB signaling is continuously activated in the prostate of IkappaBalpha+/- mouse. Supplementary Figure 2. NF-kappaB signaling activated in the prostate of Myc/IkappaBalpha bigenic mouse. Supplementary Figure 3. Continuous activation of NF-kappaB signaling promotes PCa progression in the Hi-Myc transgenic mouse. Supplementary Figure 4. The NF24 gene signature predicts significant differences in the overall cancer-specific survival of the PCa patients. Supplemental Figure 5. Molecular network analysis using Ingenuity Pathway Analysis (IPA). Supplemental Figure 6. NF-kappaB signaling is activated/inactivated in PCa cells by infecting with IKK2-EE or IKK2-KD retroviral vectors. Supplemental Figure 7. Activation of NF-kappaB signaling increases JNK phosphorylation in PCa cells. Supplemental Figure 8. Blocking JNK signaling inhibits NF-kappaB induced invasive ability efficiently in PCa cells. Tables 1 and 2. Matched human homolog genes. Supplementary Table 3. Stratification of 77 PCa patients.
Supplementary Figure 1 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 58K, Body weight gain of mice.
Supplementary Table 2 from Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Authors: Ittmann Michael , Huang Jiaoti , Radaelli Enrico , Martin Philip , Signoretti Sabina , Sullivan Ruth , Simons Brian W. , Ward Jerrold M. , Robinson Brian D. , Chu Gerald C. , Loda Massimo , Thomas George , Borowsky Alexander , Cardiff Robert D.
Published: March 2023

PDF file - 24K
Supplementary Figure 1 from BCR-ABL–Induced Deregulation of the IL-33/ST2 Pathway in CD34(+) Progenitors from Chronic Myeloid Leukemia Patients
Authors: Levescot Anaïs , Flamant Stéphane , Basbous Sara , Jacomet Florence , Féraud Olivier , Anne Bourgeois Elvire , Bonnet Marie-Laure , Giraud Christine , Roy Lydia , Barra Anne , Chomel Jean-Claude , Turhan Ali , Guilhot François , Girard Jean-Philippe , Gombert Jean-Marc , Herbelin André
Published: March 2023

PDF file - 200KB, The kinase activity of BCR-ABL induces upregulation of ST2 in UT7 cells.
Supplementary Figure 7 from Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Authors: Ittmann Michael , Huang Jiaoti , Radaelli Enrico , Martin Philip , Signoretti Sabina , Sullivan Ruth , Simons Brian W. , Ward Jerrold M. , Robinson Brian D. , Chu Gerald C. , Loda Massimo , Thomas George , Borowsky Alexander , Cardiff Robert D.
Published: March 2023

PDF file - 7894K, Supplementary Figure 7. Xenograft models of aggressive prostate cancer.
Supplementary Figure 6 from Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-α Status
Authors: Harrison Hannah , Rogerson Lynsey , Gregson Hannah J. , Brennan Keith R. , Clarke Robert B. , Landberg Göran
Published: March 2023

PDF file - 1336K, Details of experimental design for RT-PCR and shRNA assessment
Supplementary Figures 1 - 6 from Dynamics of Senescent Cell Formation and Retention Revealed by p14ARF Induction in the Epidermis
Authors: Tokarsky-Amiel Ronit , Azazmeh Narmen , Helman Aharon , Stein Yan , Hassan Alia , Maly Alexander , Ben-Porath Ittai
Published: March 2023

PDF file - 118K, Supplementary Figure S1. Species specificity of p14ARF and p19ARF antibodies. Supplementary Figure S2. Increase in SAβGal-positive cell numbers in control mice during early aging. Supplementary Figure S3. Rb and p130 dephosphorylation upon p14ARF induction. Supplementary Figure S4. Effects of p14ARF induction on skin histology. Supplementary Figure S5. p14ARF induces hair-follicle stem cell dysfunction through p53. Supplementary Figure S6. Senescence in TPA-treated mice.
Supplementary Figure 9 from SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non–Small Cell Lung Cancers to Cisplatin and Doxorubicin
Authors: Shin Dong Hoon , Choi Yong-Joon , Park Jong-Wan
Published: March 2023

PDF file 57K, Localization of cytochrome c by Western blotting
Supplementary Figure 4 from Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias
Authors: Rakowski Lesley A. , Garagiola Derek D. , Li Choi M. , Decker Margaret , Caruso Sarah , Jones Morgan , Kuick Rork , Cierpicki Tomasz , Maillard Ivan , Chiang Mark Y.
Published: March 2023

PDF file - 5445K, Figure S4. Cellular consequences of ZMIZ1 knockdown.
Supplementary Information from DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma
Authors: Hauer Kristina , Calzada-Wack Julia , Steiger Katja , Grunewald Thomas G.P. , Baumhoer Daniel , Plehm Stephanie , Buch Thorsten , da Costa Olivia Prazeres , Esposito Irene , Burdach Stefan , Richter Günther H.S.
Published: March 2023

PDF file - 150KB, Supplementary materials and methods, supplementary references and supplementary figure legends
Supplementary Figure 5 from DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma
Authors: Hauer Kristina , Calzada-Wack Julia , Steiger Katja , Grunewald Thomas G.P. , Baumhoer Daniel , Plehm Stephanie , Buch Thorsten , da Costa Olivia Prazeres , Esposito Irene , Burdach Stefan , Richter Günther H.S.
Published: March 2023

PDF file - 7894KB, DKK2 expression in clinical samples
Supplementary Materials, Figure Legends from Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis
Authors: Grieb Brian C. , Gramling Mark W. , Arrate Maria Pia , Chen Xi , Beauparlant Stephen L. , Haines Dale S. , Xiao Hua , Eischen Christine M.
Published: March 2023

PDF file - 142KB
Supplementary Material 7 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: March 2023

PDF file - 7565K, Supplementary material 7: Representative examples of immunoexpression obtained after incubation of prostate tissue microarrays with the anti-UGT2B15, anti-UGT2B17 or anti-vimentin antibodies: Comparison Untreated vs castrate resistant tumors.
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: March 2023

Supplementary Figure S3. Association of meta-PCNA signature with the core regulators. (A): Overlap of meta-PCNA genes with top 30 core regulators. (B) Spearman's correlation of meta-PCNA genes expression with core regulator expression. The core regulators on the x-axis are ordered by increasing average correlation coefficients. Genes with significant (Spearman's correlation test, P<0.05) are labelled in red.
Supplementary Material 3 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: March 2023

PDF file - 7458K, Supplementary material 3: Representative examples of immunoexpression obtained after incubation of prostate tissue microarrays with the anti-UGT2B15, anti-UGT2B17 or anti-vimentin antibodies: Comparison BPH vs Untreated.
Supplementary Figures 1 - 5 from Differential Contributions of STAT5A and STAT5B to Stress Protection and Tyrosine Kinase Inhibitor Resistance of Chronic Myeloid Leukemia Stem/Progenitor Cells
Authors: Casetti Luana , Martin-Lannerée Séverine , Najjar Imen , Plo Isabelle , Augé Sylvie , Roy Lydia , Chomel Jean-Claude , Lauret Evelyne , Turhan Ali G. , Dusanter-Fourt Isabelle
Published: March 2023

PDF file - 589K, shS5A, shS5B and shS5A/B differentially affect STAT5 expression in CML and normal stem/progenitor cells (S1); Characteristics of CML cells following addition of the indicated shRNA encoding lentiviral particles (S2); shS5A enhances ROS which depends on NADPH oxidase activity in CML cells (S3); Characteristics of IM-sensitive and -resistant CML cells (S4); Expression of STAT5A and STAT5B mRNA in normal and CML CD34+ stem/progenitor cells (S5).
Supplementary Figure 1 from A CD90+ Tumor-Initiating Cell Population with an Aggressive Signature and Metastatic Capacity in Esophageal Cancer
Authors: Tang Kwan Ho , Dai Yong Dong , Tong Man , Chan Yuen Piu , Kwan Pak Shing , Fu Li , Qin Yan Ru , Tsao Sai Wah , Lung Hong Lok , Lung Maria L. , Tong Daniel K. , Law Simon , Chan Kwok Wah , Ma Stephanie , Guan Xin Yuan
Published: March 2023

PDF file - 490K, Supplemental Figure 1. A significantly deregulated network of genes in CD90+ esophageal T-ICs identified by genome-wide expression profiling and Ingenuity Pathway Analysis (IPA).
Supplementary Figure S6 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: March 2023

Supplementary Figure S6 PDF file - 141K, Expression of ectopic rictor interact and activates mTORC2 (A) and protects cells from TRAIL-induced apoptosis (B)
Supplementary Video 1 from Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach
Authors: Kim Eunjung , Rebecca Vito , Fedorenko Inna V. , Messina Jane L. , Mathew Rahel , Maria-Engler Silvya S. , Basanta David , Smalley Keiran S.M. , Anderson Alexander R.A.
Published: March 2023

MOV file - 6089K, This video shows the spatio-temporal evolution of vSkin that produced Figure 3C (vSkin initialization).
Supplementary Methods from Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach
Authors: Kim Eunjung , Rebecca Vito , Fedorenko Inna V. , Messina Jane L. , Mathew Rahel , Maria-Engler Silvya S. , Basanta David , Smalley Keiran S.M. , Anderson Alexander R.A.
Published: March 2023

PDF file - 719K
Supplementary Figure 5 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: March 2023

PDF file - 357KB, Changes of mean voxel radioactivity of 15OH2O PET and tumor growth during intermittent PTK787 treatment.
Supplementary Figure 1 from Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Authors: Messaoudene Meriem , Fregni Giulia , Fourmentraux-Neves Emmanuelle , Chanal Johan , Maubec Eve , Mazouz-Dorval Sarra , Couturaud Benoit , Girod Angelique , Sastre-Garau Xavier , Albert Sebastien , Guédon Charles , Deschamps Lydia , Mitilian Delphine , Cremer Isabelle , Jacquelot Nicolas , Rusakiewicz Sylvie , Zitvogel Laurence , Avril Marie-Francoise , Caignard Anne
Published: March 2023

PDF file - 272K, Gating strategy of NK cells in total LN cell suspensions.
Supplementary Figure 3 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: March 2023

PDF file - 107KB, Quantitative evaluation of PCNA staining (green) with respect to DAPI staining (blue) throughout the depth of the EETEs.