bluuebunny/crossref_metadata_2025 huggingface dataset:
Aflatoxins in body fluids and food of Nigeria children with protein-energy malnutrition
Authors:   Ahmadu Bello University Teaching Hospital, Nigeria, Onyemelukwe GC , Ogoina D , Ibiam GE , Ogbadu GH
Published: November 2021

Aflatoxins are natural contaminants of food crops implicated in the pathogenesis of various human diseases. This study aimed to determine the associations between aflatoxins and protein- energy malnutrition ( PEM) by measurements of aflatoxins in serum, urine and food on plate of Nigerian children with PEM. A cross - sectional study was undertaken in 3 agro - ecological regions of Nigeria (Guinea savannah, Sudan savannah and Rain forest), where aflatoxins B1 , B2, G1, G2, M1, and M2 were measured in sera, urine and food on plate of 79 children with PEM (kwashiorkor n=36, marasmic kwashiorkor n=29 and marasmus n=13) and 33 healthy controls, matched for age and sex. Among healthy controls, aflatoxin detection rates were higher in the Guinea Savannah (72.2%) than in the Sudan Savannah (53.8%), albeit statistically insignificant. In relation to nutritional groups, the rates of detection of aflatoxins were higher in marasmic kwashiorkor (93.1%) and kwashiorkor patients (88.9%) , compared to marasmus (76.9%) and controls (63.6%, p=0.013). The rates of detection of B1 aflatoxin followed a similar trend viz. marasmic kwashiorkor (82.4%), kwashiorkor (69.4%), marasmus (53.8%) and controls (42.4%, p=0.007). Of all types of aflatoxins detected in serum, M2 had the highest rates of detection in all patient groups and controls. The median concentrations of aflatoxins detected in sera of each PEM group were significantly higher than those of controls, but comparisons between PEM groups were not statistically significant. The frequency and concentration of aflatoxins detected in urine and food of PEM groups and controls were not statistically different. However, controls had the lowest serum / urine aflatoxin ratio as well as lowest median aflatoxins concentrations in their food as compared to PEM patient s. In conclusion, aflatoxins are commonly detected in the body fluids and food of Nigerian children , but more frequently and at higher concentrations in children with PEM , possibly due to decreased excretion or increased exposure. Future prospective studies are desirable to determine if aflatoxins contribute to the pathogenesis of all types of PEM and not necessarily kwashiorkor alone.
Evaluation of the physico-chemical propertie (BH-660) for dextrose production
Authors:   Free University of Bozen-Bolzano, Italy, Mengistu SL , Shimelis AE ,   Addis Ababa University
Published: November 2021

Dextrose was produced from locally available hybrid variety of maize (Bako Hybrid660) in Ethiopia, using acid extraction. The variety was selected as an experimental input from Bako Agricultural Research Centre for the production of intermediate product starch using wet milling and end-product dextrose. The proximate composition values in the wet, milled, dried and cleaned white dent 2000 g BH-660 maize when steeped in 0.3% sulfur dioxide for 46 hrs at 50oC were determined. The mean values were 11.74%, 64.15%, 4.51%, 10.23%, 6.53% and 2.81%, for moisture content, total starch, germ, gluten, husk and fibre, respectively on dry weight basis. The total starch obtained from wet milling was 91.8% pure starch by mass. The proximate analysis values of moisture, crude protein, crude fat, crude fibre and total ash content of the sample were 7.65 %, 4.89%, 0.35%, 0.75 % 0.29 % , respectively on dry weight basis. Besides these, pH value was also determined to be 4.79. This obtained starch was hydrolyzed by an acid extraction method for the production of BH-660 maize dextrose. An average yield of 91.64% dextrose result was obtained and from this, 92.24% was pure dextrose by mass. Analysis result revealed that moisture, crude protein, crude fat, crude fibre and total ash content of the produced dextrose were 6.24%, 0.11%, 0.25%, 0.30% and 0.03%, respectively on dry weight basis. In addition, the pH value of 6.28 was determined. The control dextrose obtained from Ethiopian Pharmaceutical Manufacturing Share Company analysis values of moisture, crude fibre, crude fat and dextrose content were 5%, 0.24%, 0.23% and 93.73%, respectively on dry weight basis. From these data, it can be concluded that the BH660 maize variety has a significant potential for the production of high quality starch and dextrose, which can be used as a raw material for starch and dextrose processing industries.
Mineral nutrient content of commonly consumed leafy vegetables in northern Ghana
Authors:   University for Development Studies, Ghana, Amagloh FK , Nyarko ES
Published: November 2021

Leafy vegetables serve as the base of soups, a significant component of Ghanaian food recipes. The varying climatic conditions across Ghana and inefficient food distribution channels have resulted in the existence of different food crops in different regions. Anecdotally, Ghanaians generally believe that the consumption of Colocasia esculenta leaf improves iron status. In this study, the levels of mineral nutrients: calcium (Ca), iron (Fe), potassium (K), magnesium (Mg), manganese (Mn), sodium (Na) and zinc (Zn) in the leaves of Hibiscus sabdariffa, Amaranthus spinosus, Hibiscus cannabinus, Solanum macrocapon and Vigna unguiculata that are popularly used in food recipes in northern Ghana (compose of the Northern, Upper East and Upper West Regions), were compared with the levels in Colocasia esculenta leaf. The leafy vegetables/greens consumed in northern Ghana were sourced from market centres in the Northern and Upper East Regions (savannah zone); Colocasia esculenta leaf was obtained from market centres in Ashanti Region (forest zone). The leaves were shredded and air-dried for 7 days. The dried leaves were ground and analysed for the mineral nutrients using Instrumental Neutron Activation Analysis. The Ca content of Hibiscus sabdariffa was significantly higher than that of Colocasia esculenta by 1.07-fold difference (p<0.05). However, compared with Amaranthus spinosus, Hibiscus cannabinus, Solanum macrocapon and Vigna unguiculata, the level of Ca in the Colocasia esculenta leaf was 1.23- to 1.84-fold significantly higher (p<0.05). The Fe level in the leafy vegetables commonly consumed in northern Ghana was significantly lower (2.92- to 70.60-fold difference, p<0.0001) compared with the Colocasia esculenta leaf. Significant differences (p<0.05) were also observed in the levels of K, Mg and Zn between the other greens studied and the Colocasia esculenta leaf. The differences were between 1.17- to 1.48-fold (K), 1.08- to 1.54-fold (Mg) and 1.15- to 2.59-fold (Zn). This study shows that the leafy vegetables commonly consumed in northern Ghana contain lower levels of the selected mineral nutrients analysed compared with those of Colocasia esculenta leaf. There is a need to find alternative greens that are available or could be cultivated in this part of the country.
Socio-economic determinants of consumption pattern of fish among households in Ibadan North Local Government area of Oyo State, Nigeria
Authors:   Bowen University, Nigeria, Adeniyi OR , Omitoyin SA , Ojo OO
Published: November 2021

The importance of fish in meeting the nutritional requirements of the body for good health and a better standard of living cannot be overemphasized. The average consumption of protein in Nigeria is below 62 gm per day and a larger proportion of this is of plant origin. This has been found to be below the 70 gm minimum recommended by the World Health Organization (WHO) and hence adequate consumption of fish would go a long way in correcting the protein intake shortfall. This research looked into the consumption pattern of fish among households in Ibadan North Local government Area of Oyo State, Nigeria. This is with a view to examining the various factors of social and economic importance affecting the level of consumption of fish and other protein foods in the study area. Stratified sampling technique was used to group the 12 wards in the study area into three. Structured questionnaires were used to collect information from the heads of the 40 randomly selected households in each of the three groups. Data collected from 100 fully completed questionnaires were analyzed using descriptive statistics, multiple regression and Chi-Square tests. The descriptive statistics result shows that majority of the consumers were male (67%), with a mean age of 35.5 years. The mean amount of money spent on fish per month by the households was N3, 672.60 ($24.48). The regression result reveals that the total monthly expenditure on fish was positively affected by monthly expenditure on food and total monthly expenditure on animal protein. The coefficient of determination (R2) of 0.682 implies that 68.2% of the variation in the household monthly expenditure on fish was explained by the variables in the regression model while the Chi-Square (X2) calculated value of 77.7234 establishes the significant relationship between the respondents’ income and their expenditure on fish. It is expected that with the potentials of wide acceptability of consumption of catfish, fish farmers should take advantage of the market, explore better means of increasing its production and add value to their product. There is also the need for survey on the current level of fish consumption at the states and national levels. This could assist in enhancing policy formulation to increase production, sustain and improve on the current level of consumption in order to reduce the incidence of nutrition-induced health problems particularly among the low income consumers in the society.
Effect of garcinia kola seed meal on egg quality of the North African catfish (Clarias gariepinus) (Burchell, 1822) broodstock
Authors:   Federal University of Technology Akure, Nigeria, Dada AA
Published: November 2021

Study was undertaken to evaluate the effects of G. kola (Bitter kola) powder on egg quality in African catfish, C. gariepinus broodstocks. Catfish broodstocks ( mean weight, 911.25 ± 1.77 g) were randomly distributed into concrete tanks (2 x 2 x 1.2 m) at ten fish/tank in triplicate s. Five diets with 40 % crude protein containing 0, 50, 100, 150 and 200 g kg -1 G. kola seed powder in the feed were formulated and added to the tanks to give 3 % of body weight per day. Fecundity, Percentage fertilization, percentage hatch ability and egg size (diameter) of C. gariepinus were investigated. The result s of the study show that G. kola seed powder affects the fecundity, percentage hatch ability and percentage survival of C. gariepinus larval. The fish fed 200 g kg -1 G. kola seed powder had higher oocyte diameter but not significantly different (p<0.05) from those of the fish fed the other diets. However, the egg diameter was largest in the group of fish fed diet 200 g kg -1 G. kola seed powder and this ha d negative effect on the fertilization of the eggs. Significantly higher (p<0.05) percentage fertilization and percentage hatch ability were recorded for the fish fed diet of 150 g kg -1 G. kola seed powder than for the fish fed the alternative diets. The results showed that as the inclusion level of G. kola seed powder increased, the percentage egg fertilization increased, except when the fish were fed diet of 200 g kg - 1 G. kola seed powder where a sharp decrease was recorded. Survival of larval ranged from 88 % to 100 % and was not related to the G. kola seed powder inclusion in the diet. In this study, the larval of the fish fed on diets 150 and 200 g kg -1 G. kola seed powder survived better than the fish fed other supplemented diets. The result s suggest that dietary supplementation with G. kola seed powder improved fecundity, hatch ability and survival of C. gariepinus larval and has a potential pro -fertility property which can be exploited in fish seed production.
Species diversity and richness of wild birds in Dagona-Waterfowl sanctuary, Nigeria
Authors:   University of Ibadan, Nigeria, Lameed GA
Published: November 2021

The study of bird species diversity and richness in Dagona-Waterfowl Sanctuary was carried out during the midst of both early wet and late dry seasons, to provide comprehensive data on wild birds. Dagona Sanctuary is located within the BadeNguru Wetland sector. It is one of the important bird areas marked for the conservation of avifauna species in sub-Sahara region, Nigeria. Line Transect method was used to carry out birds’ survey at three different lake sites, namely: Gatsu (site:1), Mariam (site: 2) and Oxbow (site: 3). The instruments used were GarminTM 12 Global Positioning System (GPS), a pair of binoculars for bird’s identification, a field guide test- book and a 1,000 meters tape-rule. The data were tested with the Kolmogorov- Smirnov method o determine distribution level and birds’ diversity was assessed using Shannon-Weiner Diversity Index, while parametric tests were applied for all data. The results showed that bird species diversity was normally distributed in all the sites, site 2 had the highest diversity (2.74) compared to site 1: (1.84) and site 3: (1.62). Likewise, bird species richness in the area was normally distributed and significantly different (P<0.05) among the three sites. Site 1 had the highest number of bird species richness (16.36) (Species diversity is different species of birds at the site, while species richness is referring to specific species population), compared to site 2: (14.32) and site 3: (11.51). It was observed that there is a significant relationship between vegetation density and bird species diversity, because as tree density increases, diversity of bird species decreases. Therefore, there is a significant relationship between vegetation density and bird species diversity. A total of 135 bird species in 40 families was recorded during the survey. Seventy-four percent were found in site1, sixty-three percent in site 2 and seventy-one percent in site 3. The majority of wetland birds observed during this study were resident (Ardeidae family), migratory (Accipitridae family) and palearctic species (Yellow Wagtail, Warblers, Northern Shoveler and Sandpipers). It can be concluded that wild birds are good indicators of environmental condition, revealing the state of the wetland. Some sites were more disturbed, as observed in site 1 and site 3. It was, however, recommended that regular monitoring of the sites should be carried out so as to control changes in the state of the wetland ecosystem.
Anthropogenic pollution impact on physico-chemical characteristics of Lake Kivu, Rwanda
Authors:   Njala University, Sierra Leone, Olapade OJ , Omitoyin BO ,   University of Ibadan, Nigeria
Published: November 2021

Anthropogenic activities such as industrial effluent, domestic and agricultural waste disposal constitute major sources of pollution in water. The effects of these pollutants on the physico- chemical properties of Lake Kivu, Rwanda were investigated at three locations (Gisenyi, Kibuye and Cyangugu) between February 2005 and December 2006. Water samples used for physico- chemical analysis were collected from 12 stratified points on the lake. Samples collected were analysed and interpreted using appropriate international procedures. The physico -chemical properties measured were temperature, conductivity, pH, transparency, salinity, total alkalinity, dissolved organic matter (DOM), total dissolved solids (TDS), dissolved oxygen (DO), biological oxygen demand (BOD), nitrate – nitrogen, phosphate – phosphorus and sulphate. Mean water temperature measured (24.7 + 0.58 o C) was highest in Kibuye and lowest (24.5 + 0.31 o C) in Cyan gugu. The lake water was moderately hard with mean total alkalinity values of 88.1 ± 1.63mgL -1 ; 79.7 ± 2.36mgL -1 and 81.0 ± 2.46mg L -1 recorded in Gisenyi, Kibuye and Cyangugu respectively; salty and alkaline with mean pH values of 8.87 ± 0.07 in Gisenyi; 8.86 ± 0.06 in Kibuye and 8.91 ± 0.06 in Cyangugu. Total dissolved solids (TDS) level in the lake was above the 500mg L -1 prescribed by WHO while the mean biochemical oxygen demand (BOD) reading was within the range for unpolluted or moderately polluted lake. Water from the lake showed mineralization with mean conductivity values ranging from 1058 - 1184μS cm -1 in Gisenyi; 1058 - 1147μS cm -1 in Kibuye and 1031 - 1116μS cm -1 in Cyangugu. The mean dissolved oxygen values were below the 5mgl -1 limit recommended by WHO for fresh water fish species. SO 4- -2 and NO 3 – N concentration in the lake water does not constitute any serious health risk to both man and the aquatic organisms it supports. However, there is the need to constantly monitor the lake water to mitigate any build up of the ions to a hazardous level.
Nutrient composition, functional, sensory and microbial status of popcorn-based (Zea may everta) complementary foods enriched with cashew nut (Anacardiumoccidentale L.) flour
Authors:   Federal University of Technology, Nigeria, Ijarotimi OS , Oluwalana IB , Ogunedojutimi MO
Published: November 2021

Protein-energy malnutrition among Nigerian children is a major health challenge. This nutrition problem is attributed to the inappropriate complementary feeding practices, low nutritional quality of traditional complementary foods and high cost of quality protein-based complementary foods. Therefore, the aim of this study was to formulate complementary foods from popcorn flour and cashew nut. A quantity (500g) of each popcorn and cashew nut seeds (500g) was processed into fermented, germinated and roasted flours. The blends (40% popcorn, 60% cashew nut) were biochemically evaluated for proximate, minerals and amino acids profile. The microbiological properties and sensory attributes were determined using standard methods. For Protein, the results were 22.48% for germinated popcorn-cashew nut (GPC),20.76% for roasted popcorn-cashew nut (RPC) and 21.82% for fermented popcorn-cashew nut (FPC); values for ogi and Nutrend were 12.60% and 16.27% respectively. With respect to energy value, FPC, GPC, RPC, ogi and Nutrend had 533.85, 516.65, 530.49, 389.88 and 397.68 kcal, respectively. The percentages of total essential amino acids in the composition of the blends were36.9%, 40.7% and 38.9%for FPC, GPC and RPC, respectively; non-essential amino acids contents were 63.1%, 59.3% and 61.1% for FPC, GPC and RPC, respectively. The mineral content, that is, potassium, zinc and magnesium, of formulated samples were higher than those obtained for ogi and Nutrend. The antinutrient composition of FPC was lower than that of GPC and RPC. For the functional properties, water absorption capacity was between 1.83 – 1.93 g/ml, least gelation concentration 12.67 – 14.00 g/ml, swelling capacity 0.40 – 0.74 g/ml, loose bulk density 0.43 – 0.49 g/ml and packed bulk density 0.69 – 0.83 g/ml for the formulated samples. The overall acceptability of FPC was rated higher than GPC, RPC and ogi, but lower than Nutrend. For the microbial status, bacteria count was between 1.00–39.00 x 104 cfu/g, mould1.00–4.00 x 104 cfu/g and yeast 1.00–4.33 x 105 cfu/g. The study concluded that the FPC sample was better than ogi in terms of protein and mineral compositions and comparable in overall acceptance to Nutrend. Therefore, the FPC may be used as a complementary food.
Multi-camera object tracking system
Authors: Bobkov A.V. , Tedeev G.V.
Published: November 2021

The article proposes a multi-camera tracking system for an object, implemented using computer vision technologies and allowing the video surveillance operator in real time to select an object that will be monitored by the system in future. It will be ready to give out the location of the object at any time. The solution to this problem is divided into three main stages: the detection stage, the tracking stage and the stage of interaction of several cameras. Methods of detection, tracking of objects and the interaction of several cameras have been investigated. To solve the problem of detection, the method of optical flow and the method of removing the background were investigated, to solve the problem of tracking — the method of matching key points and the correlation method, to solve the problem of interaction between several surveillance cameras — the method of the topological graph of a network of cameras. An approach is proposed for constructing a system that uses a combination of the background removal method, the correlation method and the method of the topological graph of a network of cameras. The stages of detection and tracking have been experimentally implemented, that is, the task of tracking an object within the coverage area of one video camera has been solved. The implemented system showed good results: a sufficiently high speed and accuracy with rare losses of the tracked object and with a slight decrease in the frame rate.
Pagamento por Serviços Ambientais de Recursos Hídricos na Região Centro-Oeste do Brasil: uma abordagem crítica da perspectiva coaseana
Authors: Melges Fabio , Figueiredo Neto Leonardo Francisco , Benini Élcio Gustavo
Published: November 2021

O reconhecimento dos serviços ecossistêmicos para o bem-estar da sociedade vem sendo amplamente divulgado no meio científico, assim como é perceptível que o interesse da população quanto a sua relevância tem aumentado expressivamente. Este trabalho apresenta como objeto de investigação o Pagamento por Serviços Ambientais (PSA), sendo este considerado um instrumento de gestão ambiental capaz de gerar valor econômico a partir da proteção e manutenção de ecossistemas por meio de incentivos econômicos a “provedores” de serviços ambientais. Considerando-se que o PSA se materializa por intermédio de contratos, este trabalho analisou seus pressupostos teóricos, bem como os elementos institucionais que formam um mercado de PSA e sua utilização como ferramenta de política pública ambiental. Para tanto, foram investigados dois projetos no âmbito do Programa Produtor de Água da Agência Nacional de Águas (ANA), por meio das seguintes dimensões de análise: os arranjos institucionais; a metodologia de remuneração; custo de oportunidade; o monitoramento; e a eficiência dos projetos. Os resultados demonstraram que, embora o PSA seja apresentado como uma ferramenta genuína de mercado, na prática os esquemas são formados por múltiplos agentes, o que implica uma reformulação de seu marco conceitual de questões ligadas à propriedade privada para uma perspectiva mais abrangente que parta do trabalho: o serviço ambiental. Também foi identificado que as mensurações da efetividade dos custos associados ao programa em comparação com outras políticas ambientais são pouco exploradas no campo de estudos dos serviços ecossistêmicos, podendo levantar dúvidas da potência do instrumento na indução de comportamentos e preservação ambiental.
Avaliação do potencial de recuperação de edificações ao fim da vida útil: caso de uma instituição federal de ensino superior
Authors: Silva Roberto Caldeira da , Nagalli André , Couto João Pedro
Published: November 2021

O objetivo deste trabalho é apresentar uma metodologia para avaliar o potencial de recuperação de edificações que, devido ao fim de sua vida útil, estão sujeitas a adequações. Para tanto, o escopo do estudo compreendeu o acompanhamento in loco do processo de reabilitação de uma edificação de médio porte, construída na década 1950, pertencente a uma instituição federal de ensino superior (IFES) localizada na cidade de Curitiba, PR. A estratégia delineada foi a pesquisa participante (PP), aliada à técnica da observação participante (OP). Os resultados obtidos demonstraram o potencial de recuperação de 90,04%. Além disso, evitou-se a destinação de 35,7 m³ de resíduos aos aterros, o equivalente a 7% do volume do prédio. Este montante, em parte, foi decorrente das operações de desagregação bem-sucedidas, sobretudo desconstrução e desmontagem. Ainda, os procedimentos definidos nesta pesquisa buscam aumentar a vida útil dos edifícios existentes e atenuar o problema da sobrecarga dos aterros. Por fim, a metodologia proposta pode ser aplicada a edificações de pequeno a médio porte, em intervenções que visem a adequações, tais como obras de reabilitação, retrofit ou reformas.
Cara Menanam Bawang Merah Dengan Mudah Dan Praktis Dalam Polibag
Authors: Antar Sofyan Ismed Fachruzi
Published: November 2021

Bawang Merah (Allium  cepa L.) adalah tanaman semusim, dan   sebagai bumbu memasak, hampir semua masakan memerlukannya. Nilai ekonominya Rp 25.000-95.000 per kilogram.. Ketika harganya mahal, saat inilah dikeluhkan oleh kebanyakan ibu rumah tangga.Pertanaman Bawang Merah dengan media tanam tanah berwadahkan kantong plastik (polibag), satu siung Bawang Merah yang ditanam dapat menghasilkan 10 kali lipat (sesiung menjadi 10 siung bahkan lebih).Desa Pantai Harapan Kecamatan Bumi Makmur Kabupaten Tanah Laut Kalimantan Selatan, adalah wilayah Lahan Basah Pasang Surut Tipe-A (langsung). Sebagai media tanam bawang merah diperlukan pengolahan, dengan menambah kapur dan bahan organik. Dosis kapur 10 ton/ha (35 g/10 kg tanah/polibag) dan pupuk kandang 30 ton/ha (100 g/10 kg/polibag), dan ditanam satu siung bawah per polibag.Penyuluhan ini dilakukan dengan metode tatap muka langsung dan tanya jawab pada tempat di mana masyarakat saat itu berkumpul. Setelah itu penyuluh berkeliling lokasi untuk jumpa masyarakat di ruang terbuka (di teras rumah, atau di warung, dsb).
Transfer Teknologi Pembuatan Ekstrak Albumin Ikan Gabus Di Kelurahan Sekumpul
Authors: Sari Dewi Kartika , Nooryantini Nooryantini , Fitri Wahdatul , Madina Shafa
Published: November 2021

Abstrak Penerapan teknologi pembuatan ekstrak albumin merupakan solusi dalam pemanfaatan ikan gabus segar.  Teknologi ekstraksi daging ikan gabus untuk mendapatkan ekstrak albumin yang bernilai inovatif tinggi dan tepat guna untuk diberdayakan di masyarakat, khususnya pada masyarakat di Kelurahan Sekumpul yang belum terimplementasi secara maksimal dan pemanfaatan ikan gabus  terbatas sebagai ikan konsumsi.  Selain itu, harga ikan gabus relatif lebih mahal dibandingkan jenis ikan lainnya maka diperlukan teknologi yang lebih bernilai ekonomis berupa pembuatan makanan fungsional ekstrak albumin ikan gabus. Kegiatan PKM ini dengan mitra  masyarakat pembudidaya ikan dan ibu rumah tangga tergabung pada Lembaga Pemberdayaan Masyarakat (LPM) di Kelurahan Sekumpul.  Kegiatan PKM menggunakan metode penyuluhan dan demonstrasi.  Pelaksanan kegiatan dilakukan secara berkelompok karena memungkinkan adanya umpan balik dan interaksi dalam kelompok. Hasil dari kegiatan ini adalah tingkat pemahaman mitra dengan kreteria memahami dan mempraktekan pengolahan ekstrak albumin ikan gabus sebelum kegiatan PKM sebesar 20% dan setelah pelaksanaan PKM mencapai 80% atau terjadi peningkatan sebesar 60% dari jumlah responden.  Kesimpulan dari kegiatan PKM, yaitu (1) penerapan teknologi pengolahan ekstrak albumin merupakan upaya diversifikasi/ penganekaragaman produk hasil olahan perikanan berbasis ikan gabus dan (2) peran mitra bersama-sama dengan tim pengabdian melakukan evaluasi untuk keberlanjutan kegiatan PKM pengolahan ekstrak albumin ikan gabus menuju kepada pengembangan usaha kreatif di Kelurahan Sekumpul.  Kata kunci: ektrak albumin, ikan gabus, Kelurahan Sekumpul
Slow Sand Filter untuk Pengolahan Air di Desa Pekauman Ulu, Kalimantan Selatan
Authors: Nafisah Nafisah , Fitrawati Nafia , Ridwan Risaldi , Jannah Fathul , Rahimah Puspita Jamilah , Irawati Utami
Published: November 2021

Pekauman Ulu Village is one of the villages crossed by the Martapura river, where the water is used by  the people of this village for their daily activities. Pekauman Ulu Village is a densely populated area which is flooded every year. The water is very turbid with an unpleasant smell,  and consuming this water often makes some people get diarrhea. Thus, a simple technology is needed to treat this river water into clean water. This activity aims to build  Slow Sand Filter (SSF) units as a means of providing clean water for people in Pekauman Ulu Village. The activity is conducted in three parts: initial dissemination, training, and evaluation. Based on the survey done to the people joining the training, 95.25% of the people said that they were satisfied with the water being treated by SSF. As for the performance of the SSF itself, turbidity measurement of water samples showed that the turbidity of water filtered by the SSF unit reduced from an average of 41.7 NTU to 2.3 NTU.  It can be concluded that this community development program has successfully addressed the need for clean water for people in Pekauman Ulu Village.
Peningkatan Manajemen Usaha Pada Pembenihan Ikan ‘Kolam As Syifa’ Cindai Alus
Authors: Mahreda Emmy Sri , Mustika Rina , Febrianty Irma , Lindawati Lindawati , Pardian Pajar
Published: November 2021

AbstractThe purpose of the community partnership program activities: improving business management through bookkeeping and report training (logbooks, cash books, inventory, and balance sheets) and increase knowledge to assess business viability through profit analysis training,  Cost-Revenue Ratio, Payment Period, and Break-Even Point. The methods applied are 1. the stage of the situation and condition of the partners, 2. the stage of preparation of all materials and materials for training activities, 3. the stage of counseling and management training (training on preparing and presenting reports), analytical training according to final needs, and 4. the stage of evaluation. Community partnership program activities to improve business management for hatcheries at the As Syifa Pond Business provide increased understanding and skills of fish breeders about professional business management through increasing ability in compiling simple financial reports/bookkeeping and in analyzing business financially. This increase in understanding and skills is not only felt for current operations but also business development in the future.Keywords: management, business, bookkeeping, feasibility, As Syifa  Abstrak Tujuan kegiatan PKM adalah: perbaikan manajemen usaha melalui pelatihan penyusunan pembukuan dan laporan keuangan (log book, buku kas, buku persediaan dan neraca) dan meningkatkan pengetahuan untuk menilai kelayakan usaha melalui pelatihan menganalisis keuntungan, Revenue Cost Ratio, Payback Period dan Break Even Point. Metode kegiatan yang diterapkan adalah: 1. tahap analisis situasi dan kondisi mitra, 2.  tahap persiapan semua bahan dan materi untuk kegiatan pelatihan, 3. tahap penyuluhan dan pelatihan manajemen usaha (pelatihan pembuatan dan penyajian laporan keuangan), pelatihan menganalisis kelayakan usaha secara finasial, dan 4. tahap evaluasi PKM. Kegiatan PKM perbaikan manajemen usaha terhadap pembenih ikan pada Usaha Kolam As Syifa memberikan peningkatan pemahaman dan keterampilan pembenih ikan tentang manajemen usaha yang profesional  melalui peningkatan kemampuan dalam menyusun laporan keuangan/pembukuan sederhana dan dalam menganalisis kelayakan usaha secara finansial.  Peningkatan pemahaman dan keterampilan ini bukan hanya dirasakan untuk operasional saat ini, tetapi juga untuk pengembangan usaha di masa depan.Kata kunci: manajemen, usaha, pembukuan, kelayakan, As Syifa
Pendampingan Pembuatan E-Marketplace dan Laporan Keuangan pada UP2K "Mulan" Khususnya Dasa Wisma "Mawar"
Authors: Yuliani Rahma , Anwar Kasyful , Rahmatiasari Adisti
Published: November 2021

Program Pengabdian Kepada Masyarakat in partner with Usaha Peningkatan Pendapatan Keluarga (UP2K) “Mulan” which consists of Dasa Wisma “Mawar” in the Kelayan Dalam, Banjarmasin city. Mitra is a Dasa Wisma community that has members from women who have micro businesses. The home-based businesses that are carried out by the Dasa Wisma women are in the form of dry and wet food products, including Sago Tempe Chips, Rengginang, Banana Chips, Betel Nut, Porridge Bingka, Rolls, Cakes, Resoles And Pies. Product sales are still carried out conventionally, namely deposited at a souvenir center shop, sold directly in traditional markets or receiving orders from certain parties, there are no records or bookkeeping, the production process still uses simple tools. Based on the analysis of the situation, the problems faced by partners are the partner marketing aspect regarding the e-marketplace, the financial aspect related to financial reports, and the production aspect is still being done with household appliances.Thus, the solution offered to solve partner problems is to conduct e-commerce socialization & training along with the preparation of financial reports. The activity method begins with the preparation stage, then the implementation stage, and finally the mentoring and reporting stage which is planned to be completed within a period of 8 months. The results after implementing the program have been achieved, namely, business actors have increased understanding of the importance of e-commerce, especially online marketing and understanding finances. In addition, partners who previously did not have a Shopee and Tokopedia account after the training already have an account registered with Shopee and can be used in business activities. Next partners are given a cash book so they can record costs and sales.
Arahan Penyusunan dan Perancangan Masterplan Desa Wisata Madu Retno Berbasis Wisata Budaya
Authors: Mentayani Ira , Saud Mohammad Ibnu , Rahman Akbar , Hadinata Irwan Yudha
Published: November 2021

Madu Retno Village is the first transmigration village in the Batulicin area which was formed in 1980. Initially, village management was under the guidance of the Transmigration Department with a duration of 1 year. The village is growing but not maximal in its stages. Judging from its potential, Madu Retno Village has a strong Hindu socio-cultural character. In its development, the existing potential has not been mapped thoroughly so that there is no complete planning and development scheme, it does not yet have the direction of goals contained in the development scheme, the thematic growth direction, and indicators to improve adequate infrastructure. The overall urgency can be realized through the preparation of a village master plan which will be prepared with the residents so that they will find and appreciate the expectations of the residents. The concept of an independent village is a top priority in the preparation of this village master plan, then the concept of a cultural tourism village becomes the next development effort so that Madu Retno Village will develop tourism and community culture independently.
A Topological Approach to Shrinking Higher Dimensions of Space to Observable Space-Time: Can the Dimensional Anisotropy of Space Satisfy Mach’s Principle?
Authors: Deli Eva , Peters James F.
Published: November 2021

We create a model universe by equipping a topological surface (system) with compact dimensions insulated by an information blocking horizon. The insulated compact WF can produce entanglement independent of distance. Interaction between the system and the WF changes the curvature of the first and the quantum state (frequency) of the second in an interconnected relationship. Thus, the field curvature measures the evolution of the particle WF as time. Positive field curvature creates pressure, whereas negative field curvature generates a vacuum, satisfying the Borsuk-Ulam Theorem and the Page and Wootters mechanism of static time. The accumulation of pressure or vacuum generates poles with contrasting dimensionalities, two-dimensional black hole horizons (time infinite), and four-dimensional cosmic voids (time zero). The orthogonality of the field and the compact WF give rise to global self-regulation that fine-tunes the cosmic parameters and can promote fractal topology. The four-dimensional vacuum in cosmic voids can produce an accelerating expansion without dark energy. When gravity effects are eliminated, we find a new, so far unexplored, order-increasing side of entropy. The verifiable and elegant hypothesis satisfies Mach's principle.
Competitive Approaches of Strategic Alliance in the Big Data Environment, a Moderating Role of Big Data Predictive Analytics in the Case of Telecommunication Sector of Pakistan
Authors: Abbas Hassan , Ze Ye , Ahmad Waqar
Published: November 2021

Based on the resource-based theory, the current study examines the relationship between competitive strategies and strategic alliance performance. Furthermore, big data predictive analytics is treated as a boundary condition between competitive strategies and strategic alliance performance. Big data of predictive analytics in operations and industrial management has been a focal point in the current era. There has been little attention has about big data predictive analytics influences on competitive strategies and strategic alliance performance, especially in developing countries like Pakistan. A survey instrument was used to record the responses from 331 employees of the telecom sectors companies working in Pakistan. Study findings show that big competitive strategies have a positive and significant relationship with strategic alliances performance. It was also found that big data predictive analytics plays the role of moderator between competitive strategies and strategic alliance performance. The study add a new perspective and contribution to the literature on big data predictive analytics, strategic alliance performance, and competitive strategies in Pakistan's telecom sector companies. Further, the study results explain that big data analytics is just like the companies' lifeblood in the current era. The efficient and effective use of big data analytics, companies can boost their standards in a competitive environment.
MTHFD1 1958 G>A Genetic Polymorphism (rs2236225) Dichotomy in Schizophrenia: Lower Manifestation Risks, but More Severe Negative Symptoms
Authors: Zhilyaeva Tatiana , Chekanina Oksana , Rukavishnikov Grigory , Blagonravova Anna , Mazo Galina Elevna
Published: November 2021

Despite a large amount of data on the association of folate metabolism disturbances with different aspects of schizophrenia, the role of the MTHFD1 1958 G>A polymorphism in this disorder is barely studied. The aim of this study was to assess the distribution of alleles and genotypes frequencies of MTHFD1 1958 G>A in patients with schizophrenia and healthy controls and to study the association of allele/genotype carriage of this SNP with biochemical markers of one-carbon metabolism and with the severity of schizophrenia symptoms. Methods: In 57 patients with schizophrenia and 37 healthy volunteers the carriage of alleles/genotypes of the MTHFD1 1958 G>A and biochemical markers of folate metabolism disturbances were evaluated. Clinical symptoms of schizophrenia and the severity of extrapyramidal side effects of therapy were assessed in patients. Results: an association of the wild GG genotype with schizophrenia was shown (GG versus AG / AA: χ2 = 7.31; p = 0.007). The serum folate level in carriers of the wild genotype GG is lower (in all participants p = 0.024, in patients p = 0.10), and the level of cobalamin in this subgroup is higher (in all participants p = 0.047, in patients p = 0.091) than in carriers of other genotypes. Patients carrying the G allele had less severe negative symptoms (p = 0.0041) and extrapyramidal side effects of antipsychotics (p = 0.054), than patients with AA genotype. The age of psychosis manifestation is the later, the more wild alleles G are present in the genotype (p = 0.00195).
Cartographies on COVID-19 and functional divisions of the territory: an analysis on the evolution of the pandemic based on Basic Health Areas (BHA) in Castile and Leon (Spain)
Authors: Andrés López Gonzalo , Herrero Luque Daniel , Martínez Arnaiz Marta
Published: November 2021

In the face of the confusion and uncertainty that COVID-19 has caused over the last year, Geography has proven to be a useful aid in the interpretation of the spatial dynamics that explain the transmission of the virus. Applied cartography and GIS analysis of epidemiological data have been consolidated as essential tools for interpreting the health crisis. This paper explores the usefulness of maps for the study of the evolution of the pandemic in Castile and Leon, one of the Spanish regions with the highest levels of infection and mortality. Based on the statistical variables of sick and dead people at the scale of the Basic Health Area (BHA), a first analytical approach is carried out by means of a sequence of dynamic maps during the first wave. Afterwards, a systematic study is carried out using thematic mapping for the period of the three waves, a period between March 2020 and March 2021. The analysis unravels the differential impact of the disease between rural and urban areas and reveals the problems of the mismatch between the functional divisions of the territory (BHA, as units of health analysis) and the scale of administrative management (municipalities, as the effective scale of action).
­­BVES Is a Novel Interactor of ANO5 and Regulates Myoblast Differentiation
Authors: Li Haiwen , Xu Li , Gao Yandi , Zuo Yuanbojiao , Yang Zuocheng , Zhao Lingling , Chen Zhiheng , Guo Jacky Shuliang , Han Renzhi
Published: November 2021

Background: Anoctamin 5 (ANO5) is a membrane protein belonging to the TMEM16/Anoctamin family and its deficiency leads to the development of limb girdle muscular dystrophy R12 (LGMDR12). However, little has been known about the interactome of ANO5 and its cellular functions. Results: In this study, we exploited a proximal labeling approach to identify the interacting proteins of ANO5 in C2C12 myoblasts stably expressing ANO5 tagged with BioID2. Mass spectrometry identified 41 unique proteins specifically from ANO5-BioID2 samples but not BioID2 fused with ANO6 or MG53, including BVES and POPDC3. The interaction between ANO5 and BVES was further confirmed by co-immunoprecipitation (Co-IP), and the N-terminus of ANO5 mediated the interaction with BVES through its C-terminus. ANO5 and BVES were co-localized in muscle cells and enriched at the endoplasmic reticulum (ER) membrane. Genome editing-mediated ANO5 or BVES disruption significantly suppressed C2C12 myoblast differentiation with little impact on proliferation. Conclusions:Taken together, these data suggest that BVES is a novel interacting protein of ANO5, involved in regulation of muscle differentiation.
Clinical Experience With Venetoclax in Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia.
Authors: Fleischmann Maximilian , Scholl Sebastian , Frietsch Jochen J , Hilgendorf Inken , Schrenk Karin , Hammersen Jakob , Prims Florian , Thiede Christian , Hochhaus Andreas , Schnetzke Ulf
Published: November 2021

Background: Diagnosis of acute myeloid leukemia (AML) is associated with poor outcome in elderly and unfit patients. Recently, approval of the BCL-2 inhibitor Venetoclax (VEN) in combination with hypomethylating agents (HMA) led to a significant improvement of response rates and survival. Further, application in the relapsed or refractory (r/r) AML setting or in context of allogeneic stem cell transplantation (alloHSCT) seems feasible.Methods and Patients: Fifty-six consecutive adult AML patients on VEN from January 2019 to June 2021 were analyzed retrospectively. Patients received VEN either as first-line treatment, as subsequent therapy (r/r AML excluding prior alloHSCT), or at relapse after alloHSCT. VEN was administered orally in 28-day cycles either combined with HMA or low-dose cytarabine (LDAC).Results: After a median follow-up of 4.7 (range, 0.8 – 24.3) months median overall survival (OS) from start of VEN treatment was 13.3 (2.2 - 20.5) months, 5.0 (0.8 - 24.3) months and 4.0 (1.5 - 22.1) months for first-line, subsequent line treatment and at relapse post-alloHSCT, respectively. Median OS was 11.5 (10 - 22.3) months from start of VEN when subsequent alloHSCT was carried out. Overall response rate (composite complete remission + partial remission) was 51.8% for the total cohort (61.1% for VEN first-line treatment, 52.2% for subsequent line and 42.8% at relapse post-alloHSCT). Subgroup analysis revealed a significantly reduced median OS in FLT3-ITD mutated AML with 3.4 (1.9 - 8.0) months versus 10.4 (0.8 - 24.3) months for non-mutated cases, (HR 3.59, 95% CI 0.94 - 13.72, p = 0.001). Patients harboring NPM1 or IDH1/2 mutations lacking parallel FLT3-ITD mutations showed a survival advantage over patients without those mutations (11.2 (5 - 24.3) months versus 5.0 (0.8 - 22.1) months, respectively, (HR 0.53, 95% CI 0.23 – 1.21, p = 0.131). The most common adverse events were hematological, with grade 3 and 4 neutropenia and thrombocytopenia reported in 44.6% and 14.5% of patients, respectively. Conclusion: Detailed analyses on efficacy for common clinical scenarios such as first-line treatment, subsequent therapy (r/r AML), and application prior to and post-alloHSCT are presented. The findings suggest VEN treatment combinations efficacious not only in first-line setting but also in r/r AML. Furthermore, VEN might play a role in a subgroup of patients with failure to conventional chemotherapy as a salvage regimen aiming for potential curative alloHSCT.
A Deep Learning Post-Discharge Mortality Prediction Method Considering Diagnosis Information for ICU Patients
Authors: Liu Mucan , Guo Chonghui , Cui Shaoze
Published: November 2021

Background and Objective: Mortality prediction is widely used to stratify patients into different risk categories and to provide prognosis evaluation. Nowadays, scoring systems, which predict mortality with some scores reflecting the severity of diseases and physiological states of patients in ICU, have been widely applied for in-hospital mortality prediction. Many research works which focus on designing better machine learning models and algorithms for mortality prediction also have achieved great performance. However, it is not enough to make post-discharge prognosis of mortality only with the aid of better models and algorithms while richer patient related information can make big differences. In this study, we propose a deep learning method considering patient diagnosis information for post-discharge prognosis of mortality. This method can help to significantly improve the performance of prediction. Further more, we propose a method of calculating disease Shapley values to evaluate the mortality risk brought by disease factors. Methods: Deep learning models including long short-term memory (LSTM) and temporal convolutional network (TCN) are trained with patient physiological time series data and diagnosis information of different prevalence to predict post-discharge mortality risk of different time windows. Disease Shapley values to evaluate the mortality risk brought by disease factors are the weighted average of marginal contributions of diseases to patient mortality. Experiments of several post-discharge mortality prediction tasks of different time windows are conducted on the large freely accessible MIMIC-III dataset. To provide more sufficient comparison, the diagnosis information is also introduced for traditional machine learning models. Results: In our experiment, LSTM achieves highest AUROC and the improvements of which are 8.67%, 9.68%, 13.33%, 12.32% and 12.25% with the help of diagnosis information for five post-discharge mortality prediction tasks of different time window. Several patient examples are shown to present the mortality risk brought by disease factors, of which the analysis results are in line with clinical experiences. Conclusions: In general, our proposed method can improve performance of ICU patient post-discharge mortality prediction and help to evaluate how much do different kinds of diseases which a patient suffers from increase his mortality, thus providing support for clinical decisions.