bluuebunny/crossref_metadata_2025 huggingface dataset:
Advances in Materials and Interface Understanding in Protonic Ceramic Fuel Cells
Authors: Tsvetkov Nikolai , Kim Dongyeon , Jeong Incheol , Kim Jun Hyuk , Ahn Sejong , Lee Kang Taek , Jung WooChul
Published: November 2022

Protonic ceramic fuel cells (PCFCs) are promising eco‐energy electrochemical energy conversion systems that can efficiently operate in intermediate (500–700 °C) to low (500 °C) temperature ranges. In this review the most recent advances in materials research for the ceramic components of PCFCs (i.e., electrolyte, cathode, and anode) and their interface engineering are introduced. Recent approaches to improve the protonic of conductivity, and activity and stability of electrolyte and electrode materials are first presented. In addition, new attempts to stabilize/activate electrode/electrolyte interfaces and electrode surfaces are also discussed. Details of the theoretical background behind the electron and ion transfer processes at electrodes are also discussed. Finally, the challenges and perspectives of PCFC development are suggested from the point of view of materials engineering.
Micro‐Optics 3D Printed via Multi‐Photon Laser Lithography
Authors: Gonzalez‐Hernandez Diana , Varapnickas Simonas , Bertoncini Andrea , Liberale Carlo , Malinauskas Mangirdas
Published: November 2022

The field of 3D micro‐optics is rapidly expanding, and essential advances in femtosecond laser direct‐write 3D multi‐photon lithography (MPL, also known as two‐photon or multi‐photon polymerization) are being made. Micro‐optics realized via MPL emerged a decade ago and the field has exploded during the last five years. Impressive findings have revealed its potential for beam shaping, advanced imaging, optical sensing, integrated photonic circuits, and much more. This is supported by a game‐changing and increasing industrial interest from key established companies in this field. In this review, the origin and the advancement of micro‐optics fabrication with MPL are detailed by describing the chronology, distinguishing discrete application groups, providing generalized technical data on the processes and available materials, and discussing the foreseen near‐future advances.
Enhanced Photon Harvesting in Wedge Tandem Solar Cell
Authors: Chamoli Sandeep Kumar , Singh Subhash , Guo Chunlei , Li Wei
Published: November 2022

Light‐trapping elements play an important role in solar cells to enhance their light‐harvesting efficiency. Pyramidal‐shaped nano‐microstructures and gradient metasurfaces are mostly used as light‐trapping elements in solar cells. There is, however, one major concern with nanostructured solar cells: a larger surface area resulting in a larger surface recombination loss. In this article, a novel thin‐film wedge tandem‐solar cell made of perovskites and silicon is designed where the bottom cell itself works as a light‐trapping element. Optical and electrical simulations are performed to estimate performance metrics of the wedge tandem‐solar cell and compare with typically used unpatterned planar tandem‐solar cell. In terms of optical and electrical performance, wedge geometry outperforms planar geometry and shows 17.18% higher efficiency. Compared to a typical planar tandem cell, such a design can lead to thin and low‐weight tandem solar cells, which can be very useful in space applications. The proposed design can be fabricated using an optimized electrospray deposition process.
Emerging Sonodynamic Therapy‐Based Nanomedicines for Cancer Immunotherapy
Authors: Yang Yunrong , Huang Jia , Liu Min , Qiu Yige , Chen Qiaohui , Zhao Tianjiao , Xiao Zuoxiu , Yang Yuqi , Jiang Yitian , Huang Qiong , Ai Kelong
Published: November 2022

Cancer immunotherapy effect can be greatly enhanced by other methods to induce immunogenic cell death (ICD), which has profoundly affected immunotherapy as a highly efficient paradigm. However, these treatments have significant limitations, either by causing damage of the immune system or limited to superficial tumors. Sonodynamic therapy (SDT) can induce ICD to promote immunotherapy without affecting the immune system because of its excellent spatiotemporal selectivity and low side effects. Nevertheless, SDT is still limited by low reactive oxygen species yield and the complex tumor microenvironment. Recently, some emerging SDT‐based nanomedicines have made numerous attractive and encouraging achievements in the field of cancer immunotherapy due to high immunotherapeutic efficiency. However, this cross‐cutting field of research is still far from being widely explored due to huge professional barriers. Herein, the characteristics of the tumor immune microenvironment and the mechanisms of ICD are firstly systematically summarized. Subsequently, the therapeutic mechanism of SDT is fully summarized, and the advantages and limitations of SDT are discussed. The representative advances of SDT‐based nanomedicines for cancer immunotherapy are further highlighted. Finally, the application prospects and challenges of SDT‐based immunotherapy in future clinical translation are discussed.
Simultaneously Constructing Active Sites and Regulating Mn–O Strength of Ru‐Substituted Perovskite for Efficient Oxidation and Hydrolysis Oxidation of Chlorobenzene
Authors: Duan Xiaoxiao , Zhao Ting , Niu Ben , Wei Zheng , Li Ganggang , Zhang Zhongshen , Cheng Jie , Hao Zhengping
Published: November 2022

Chlorinated volatile organic compounds (CVOCs) are a class of hazardous pollutants that severely threaten environmental safety and human health. Although the catalytic oxidation technique for CVOCs elimination is effective, enhancing the catalytic efficiency and simultaneously inhibiting the production of organic byproducts is still of great challenge. Herein, Ru‐substituted LaMn(Ru)O3+δ perovskite with Ru–O–Mn structure and weakened Mn–O bond strength has been developed for catalytic oxidation of chlorobenzene (CB). The formed Ru–O–Mn structure serves as favorable sites for CB adsorption and activation, while the weakening of Mn–O bond strength facilitates the formation of active oxygen species and improves oxygen mobility and catalyst reducibility. Therefore, LaMn(Ru)O3+δ exhibits superior low‐temperature activity with the temperature of 90% CB conversion decreasing by over 90 °C compared with pristine perovskite, and the deep oxidation of chlorinated byproducts produced in low temperature is also accelerated. Furthermore, the introduction of water vapor into reaction system triggers the process of hydrolysis oxidation that promotes CB destruction and inhibits the generation of chlorinated byproducts, due to the higher‐activity *OOH species generated from the dissociated H2O reacting with adsorbed oxygen. This work can provide a unique, high‐efficiency, and facile strategy for CVOCs degradation and environmental improvement.
Porous Metal Current Collectors for Alkali Metal Batteries
Authors: Chen Jianyu , Wang Yizhou , Li Sijia , Chen Huanran , Qiao Xin , Zhao Jin , Ma Yanwen , Alshareef Husam N.
Published: November 2022

Alkali metals (i.e., Li, Na, and K) are promising anode materials for next‐generation high‐energy‐density batteries due to their superior theoretical specific capacities and low electrochemical potentials. However, the uneven current and ion distribution on the anode surface probably induces undesirable dendrite growth, which leads to significant safety hazards and severely hinders the commercialization of alkali metal anodes. A smart and versatile strategy that can accommodate alkali metals into porous metal current collectors (PMCCs) has been well established to resolve the issues as well as to promote the practical applications of alkali metal anodes. Moreover, the proposal of PMCCs can meet the requirement of the dendrite‐free battery fabrication industry, while the electrode material loading exactly needs the metal current collector component as well. Here, a systematic survey on advanced PMCCs for Li, Na, and K alkali metal anodes is presented, including their development timeline, categories, fabrication methods, and working mechanism. On this basis, some significant methodology advances to control pore structure, surface area, surface wettability, and mechanical properties are systematically summarized. Further, the existing issues and the development prospects of PMCCs to improve anode performance in alkali metal batteries are discussed.
Triggering the Phase Conversion of GeP from Monoclinic to Cubic by Zn Substitution toward a High‐Rate Ge1−xZnxP Solid Solution Anode for Li‐Ion Batteries
Authors: Wei Yaqing , Yao Runzhe , Zhao Yinghe , Yang Ruoou , Liu Junlong , Liu Xuhao , Li Huiqiao
Published: November 2022

The monoclinic GeP with large capacity, low plateau, and high initial coulombic efficiency (ICE) has been proved to be alternative anode for Li‐ion batteries. However, the heavy use of Ge raw material with its high price, hinders its further development. Herein, the Zn atom is proposed for substitution into GeP and replaces part of the Ge owing to its low price, suitable plateau, and similar radius. Interestingly, a novel Ge1−xZnxP solid solution with a wide range tunable region (0.143 < x < 0.6) is achieved, reducing the heavy use of Ge and cutting the GeP price down. More intriguingly, such Ge1−xZnxP possesses a new phase, different from monoclinic GeP, which is first verified to be a cubic system in F‐43m. Compared to semi‐conducting GeP, this cubic Ge1−xZnxP phase possesses metallic conductivity, thus enabling a better rate performance than monoclinic GeP (e.g., 881 vs 283 mAh g−1 at 2000 mA g−1), while keeping the great advantages of large capacity, low plateau, and high ICE of GeP as well. Consequently, the assembled LiCoO2//Ge1−xZnxP full cell exhibits large capacity over 1000 mAh g−1. This unique phase control strategy by atomic substitution can be easily extended to manipulate electrochemical behaviors of other multi‐phase materials toward advanced energy storage.
Understanding the Highly Electrocatalytic Active Mixed Triple Conducting NaxCa3–xCo4O9–δ Oxygen Electrode Materials
Authors: Park Kwangho , Bae Hohan , Kim Hyun‐Kyu , Choi In‐Gyu , Jo Minkyeong , Park Gwang‐Min , Asif Muhammad , Bhardwaj Aman , Lee Kug‐Seung , Kim Yeong‐Cheol , Song Sun‐Ju , Wachsman Eric D. , Park Jun‐Young
Published: November 2022

Despite their high electrocatalytic activity for oxygen electrode reactions, the low phase stability and high thermal expansion of perovskite structured materials have created difficulties in cell fabrication scale‐up and long‐term operational stability of reversible ceramic cells. Herein, an exceptionally high‐performance electrocatalyst is presented based on a misfit‐layered structure, Na0.15Ca2.85Co4O9–δ (NCCO). NCCO cells enable exceptional fuel cell performance down to 400 °C, with peak power densities of 0.18–5.15 W cm−2 at 400–800 °C, as well as electrolysis performance of minus current density 5.96–15.07 A·cm−2 (at 1.4 V) at 600–750 °C, exceeding the values of all previously described reversible (oxygen and proton) ceramic cells. Furthermore, the durability of NCCO cells is demonstrated for over 900 h at high current densities of 1 and 2 A cm−2 in fuel cells and –0.5 and –4 A cm−2 electrolysis cell modes under load cycle and constant current reversible operation, respectively. Doping with basic monovalent Na+ ions in the Ca‐site in Ca3Co4O9+δ generates a high density of extra charge carrier species with the increased Co oxidation state and facilitates the proton uptake and diffusion properties of misfit‐layered materials. This finding can deliver a new opportunity to develop innovative bifunctional oxygen electrode catalysts, while providing more favorable reaction pathways for the diffusion of charged species.
Near‐Atomic‐Scale Evolution of the Surface Chemistry in Li[Ni,Mn,Co]O2 Cathode for Li‐Ion Batteries Stored in Air
Authors: Singh Mahander P. , Kim Se-Ho , Zhou Xuyang , Kwak Hiram , Kwiatkowski da Silva Alisson , Antonov Stoichko , Aota Leonardo Shoji , Jung Chanwon , Jung Yoon Seok , Gault Baptiste
Published: November 2022

Layered LiMO2 (M = Ni, Co, Mn, and Al mixture) cathode materials used for Li‐ion batteries are reputed to be highly reactive through their surface, where the chemistry changes rapidly when exposed to ambient air. However, conventional electron/spectroscopy‐based techniques or thermogravimetric analysis fails to capture the underlying atom‐scale chemistry of vulnerable Li species. To study the evolution of the surface composition at the atomic scale, cryogenic atom probe tomography is used herein and the surface species formed during exposure of a LiNi0.8Mn0.1Co0.1O2 (NMC811) cathode material to air are probed. The compositional analysis evidences the formation of Li2CO3. Site‐specific examination from a cracked region of an NMC811 particle also reveals the predominant presence of Li2CO3. These insights will help to design improved protocols for cathode synthesis and cell assembly, as well as critical knowledge for cathode degradation.
Age‐related features of the content of substrates of energy metabolism and body mass index in women residing in the Subarctic and Arctic regions of Russia
Authors: Vlasova Olga S. , Bichkaeva Fatima A. , Nesterova Ekaterina V. , Shengof Boris A. , Bichkaev Artem A. , Baranova Nina F.
Published: November 2022

Objectives

Age is associated with a number of health risks linked to obesity caused by an imbalance in the main energy substrates—fatty acids (FA) and glucose (Glu). Therefore, the objective of this study was to identify age‐related features of the metabolism of fatty acids and Glu, their correlations and the relation with the body mass index (BMI) in women of the local Caucasoid population from two northern regions of Russia with different nature, climate, and geography.

Methods

We examined women aged 21–60 years born and permanently residing in the Subarctic region (SR) and the Arctic region (AR). The participants were divided into three age groups: 21–35, 36–45, and 46–60 years. The levels of FAs, Glu, and triglycerides (TG) in the blood serum were determined by spectrophotometric and gas chromatographic methods; the values of BMI and TyG (triglyceride glucose) index were calculated. To analyze data, we used the descriptive and correlation analyses by nonparametric methods, as well as multiple linear regression analysis.

Results

With age, the surveyed women demonstrated elevated levels of triglyceride, the majority of the studied fatty acids, BMI and TyG index. For three fatty acids, age‐related changes were noted in one of the regions only: stearic and linoleic acids in the SR, and docosahexaenoic acid in the AR; no significant changes were observed for dihomo‐γ‐linolenic and arachidonic acids. We found elevated Glu levels in women aged 46–60 years residing in the SR. Regional differences were due to higher concentrations of FAs and Glu in the AR. All identified correlations were positive. BMI values were associated with FAs and TG, and in women aged 46–60 years, they were additionally associated with Glu. The latter also correlated with some FAs and TG in this group. TyG index associations with saturated FAs (SFAs) became stronger with age.

Conclusions

Age has a significant impact on the homeostasis of key energy substrates (Glu, TG, SFAs, monounsaturated FAs), on BMI and TyG index, which are indicators of obesity and insulin resistance. Depending on the region of residence (Subarctic or Arctic), we found changes in the FA profile undersaturation (especially long‐chain polyunsaturated FAs) and some specific features of Glu homeostasis (for the age groups of 21–35 and 46–60 years) in women of Caucasoid race in the Russian North. Multiple regression analysis showed that BMI, as well as the region of residence and age, are significant predictors for almost all biochemical parameters, especially for TG and TyG index.
Crisis, Change, the IT Revolution, and Covid‐19's Enduring Impact On Dispute Resolution and General Business Practice
Authors: Clift Rhys
Published: November 2022

Disaster, in tandem with innovation, is the principal catalyst of change.
Ten Reasons for Serving as a FINRA Arbitrator
Authors: McArthur John Burritt
Published: November 2022

Over the course of my career, I have heard many critical, even prejudicial, comments about arbitrators who adjudicate cases for the Financial Industry Regulatory Authority, best known as FINRA. Yet I continue to be proud to serve as a FINRA arbitrator.
Nanotechnology‐Assisted Immunoengineering for Cancer Vaccines
Authors: Mamuti Muhetaerjiang , Chen Weizhi , Jiang Xiqun
Published: November 2022

Recently, approaches based on nano‐immunoengineering have been developed to optimize the potency of vaccines while minimizing toxicity. To achieve desirable immune responses, vaccines should be able to traffic into lymph nodes (LN) and provide antigen and inflammatory signals for a sufficient temporal duration, to activate the desired cellular and humoral immunity. In that case, the application of nanotechnology in vaccine design provides the possibility of co‐delivering of antigen and adjuvants to the targeted organs, tissues, cells, or even intracellular compartments at the determined time to optimize the qualities of immune responses. Herein, the recent advances on nanovaccine design, including a brief summary of natural and synthetic biomaterials for antigen and adjuvant packing, are reviewed. The emerging approaches for regulating pharmacokinetics of vaccines will be further discussed especially for LN targeting as well as antigen uptake by antigen‐presenting cells. Those advances provide a prospect of shaping immune response by immunoengineering‐based nanovaccines.
Clinical Issues—December 2022
Authors: Miner Mary Alice
Published: November 2022

THIS MONTH

Surveying the AORN membership for research studies

Key words: perioperative research study, research grant, incentive, sample size, power analysis.

Informed consent document validity

Key words: surgical consent forms, anesthesia consent forms, canceled procedures, rescheduled procedures, documentation.

Internet technology updates and fire alarms

Key words: 3G phaseout, 5G technology, fire alarm system, cellular communicator, communication loss.

Documenting versus recording

Key words: documentation, record keeping, logbook, patient health care record (HCR), patient health care information.
Influence of3Dprinting process parameters on the tribological properties of acrylic resin
Authors: Yu Liang , Zhu Yanan , Wang Lei , Zhang Jin , Zhou Jiping , Fu Yan
Published: November 2022

This article studied the mechanism of the influence of light‐curing 3D forming parameters of acrylic resin on its tribological and mechanical properties. A three‐factor hybrid orthogonal table was designed, that is, the three key process parameters of printing monolayer thickness (P), heat treatment (H), and ultraviolet curing treatment (U). The priority of three process parameters affecting tribological performance was studied based on Gray Correlation Theory. The results showed that the order of priority was P, U, and H. The tribological and mechanical properties of acrylic resin decreased with the increase of printing monolayer thickness, while the printing efficiency increased with the increase of the printing monolayer thickness. Based on Gray Correlation Theory, the “Wear Resistance Efficiency” (WRE) parameter was defined to comprehensively evaluate the wear resistance and printing efficiency of the samples. When the thickness of the printing monolayer was 30 μm, the comprehensive properties of the material reached the optimal value. The U increased the cross‐linking degree of the acrylic interlayer molecules, and the H reduced the residual stress generated during the printing of the samples. The research results provided data support for the application of 3D printing acrylic resin and its nanocomposites in the field of tribology.
Effect of poly(ether block amide)‐graphene/ZnO membranes in mixed gas separation performance
Authors: Mendoza‐Mendoza Esmeralda , España‐Sánchez Beatriz Liliana , Montes‐Luna Angel de Jesús , Castruita‐de León Griselda
Published: November 2022

In this work, graphene/zinc oxide nanoparticles (G/ZnO NPs) were synthesized by a metathesis‐assisted molten salt route. The methodology followed has outstanding features such as innovative, environmentally friendly, high‐yield, efficient, and straightforward. In addition, poly(ether‐block‐amide) (PEBA)‐based mixed matrix membranes (MMMs) filled with different amounts of G/ZnO NPs (up to 2%) were successfully prepared. Thermogravimetric analysis and X‐ray diffraction were performed to determine the thermal and structural properties of the pristine and MMMs. Scanning electron microscopy and electron dispersive spectroscopy were used for morphological studies and for identifying the as‐prepared G/ZnO NPs. Incorporating G/ZnO NPs (PEBA‐G/ZnO 2% 476 Barrer) provided benefits to the permeability properties and showed an increase of 37% concerning the polymeric membrane (318.06 Barrer). The gas separation performance improved by increasing the amount of G/ZnO NPs. A synergistic effect between PEBA properties and G/ZnO NPs led to enhanced CO2 selectivity for ternary mixed gas separation (CO2/CH4/N2). Selectivity of the MMMs showed an increase of 34% higher than to pristine (PEBA) membrane favoring the permeation of CO2. G/ZnO NPs can be potentially helpful in membranes applied in the CO2 mixed gas separation.
The Big Seaweed Search: Evaluating a citizen science project for a difficult to identify group of organisms
Authors: Brodie Juliet , Kunzig Sarah , Agate Jules , Yesson Chris , Robinson Lucy
Published: November 2022

The Big Seaweed Search invites people to survey UK seashores for 14 conspicuous seaweeds. The science investigates: (i) impact of sea temperature rise; (ii) spread of non‐native species; and (iii) impact of ocean acidification. Survey data submitted between June 2016 and May 2020 were analysed to evaluate and explore project directions in relation to citizen science project development.

Of the 378 surveys submitted, 1,414 people participated, contributing 1,531 person hours. Surveys were undertaken around the UK, with the highest proportion (46.7%) in the south west and the lowest (3.7%) in the north east.

After data verification, 1,007 (54%) records were accepted. Fucus serratus had the highest number of entries correctly identified (66%) and Undaria pinnatifida the lowest (5%), inferring that at least some seaweeds can be difficult to identify, although the overall misidentification rate was relatively low (c. 15%).

Apart from Alaria esculenta, U. pinnatifida and Saccharina latissima, the large brown seaweeds were abundant on at least some shores. Non‐natives Sargassum muticum and Asparagopsis armata, were band‐forming but in low numbers. Coralline algae, whilst band‐forming on some shores, were most commonly patchy or sparse in abundance. Revisits, i.e. repeat surveys, at the same site with an interval of at least 1 year, are relatively low, with 18 sites revisited once and three sites revisited twice. Currently, data are insufficient to determine whether any changes in abundance could be detected.

This study highlights areas where project developments can enhance data quality and quantity, e.g. better identification resources, training programmes for dedicated volunteers, and an annual focus week of activities. The project framed around climate change impacts, aims to raise awareness of the ecological importance of, and threats faced by, this understudied habitat and introduce conservation concepts including the need to protect common species showing signs of decline.
Photosynthesis of hybrid silver‐based nanoparticles mediated lectins and evaluation of their hemagglutinating properties
Authors: da S Fernandes Diógenes G. , Capo Graziella S. , Tofanello Aryane , Castro Carlos E. , Foltran Bruno B. , Squina Fabio M. , Santos Maria H. C , Silva Romério R. S. , Teixeira Claudener S. , Garcia Wanius
Published: November 2022

Lectins are carbohydrate‐binding proteins belonging to the Leguminosae family. In this family stand out proteins extracted from species belonging to Diocleinae subtribe, which includes, for example, the seed lectin from Dioclea violacea (DVL) and the jack bean lectin Concanavalin A (ConA). Here, we report the photosynthesis of silver/silver chloride nanoparticles (NPs) assisted by ConA and DVL. The syntheses were simple processes using a green‐chemistry approach. Under electron microscopy, NPs heterogeneous in size, nearly spherical and covered by a thin lectin corona, were observed. Both NPs assisted by lectins were capable to cause strong rabbit erythrocytes agglutination with the same titers of hemagglutinating activities. These results indicate that both lectins maintained their biological activities even after association with the NPs and therefore are able to interact with biological membrane carbohydrates. However, for rabbit erythrocytes treated with proteolytic enzymes were observed different titers of hemagglutinating activities, suggesting differences in the spatial arrangement of the lectins on the surface of the NPs. This study provides evidences that these hybrid lectin‐coated silver/silver chloride NPs can be used for selective recognition and interaction with membrane carbohydrates and others biotechnological applications.
Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials
Authors: Sun Sophie , Sechidis Konstantinos , Chen Yao , Lu Jiarui , Ma Chong , Mirshani Ardalan , Ohlssen David , Vandemeulebroecke Marc , Bornkamp Björn
Published: November 2022

The identification and estimation of heterogeneous treatment effects in biomedical clinical trials are challenging, because trials are typically planned to assess the treatment effect in the overall trial population. Nevertheless, the identification of how the treatment effect may vary across subgroups is of major importance for drug development. In this work, we review some existing simulation work and perform a simulation study to evaluate recent methods for identifying and estimating the heterogeneous treatments effects using various metrics and scenarios relevant for drug development. Our focus is not only on a comparison of the methods in general, but on how well these methods perform in simulation scenarios that reflect real clinical trials. We provide the R package benchtm that can be used to simulate synthetic biomarker distributions based on real clinical trial data and to create interpretable scenarios to benchmark methods for identification and estimation of treatment effect heterogeneity.
Green practices as an effective business strategy to influence the behavior of hotel guests in the luxury hotel sector: Evidence from an emerging market
Authors: Dang‐Van Thac , Wang Jianming , Vo‐Thanh Tan , Jiang Xinru , Nguyen Ninh
Published: November 2022

Researchers have investigated the influence of green practices on consumer behavior in the last decades. However, findings indicate that consumers have different responses toward green practices. To advance the current literature, this study draws on the theoretical foundation of social identity theory to investigate the relationship between green practices and hotel guests' visit intention in the luxury hotel sector. The study also determines the mediating mechanisms of perceived value fit and promotion focus and the moderating mechanism of environmental behavior in this relationship. Sample data were collected from 473 hotel guests in China's luxury hotels. The results of structural equation modeling indicate that green hotel practices enhance visit intention and that perceived value fit and promotion focus positively mediate this relationship. Moreover, environmental behavior has a positive moderating effect on the link between green hotel practices and perceived value fit, as well as that between perceived value fit and visit intention. A robustness test with another sample data of 266 hotel guests confirms the hypothesis testing results. The findings of this study provide implications for researchers and business managers in understanding and managing the influence of green practices on hotel guests' behavior in the luxury hotel sector.
A systematic mapping study: The new age of software architecture from monolithic to microservice architecture—awareness and challenges
Authors: Razzaq Abdul , Ghayyur Shahbaz A. K.
Published: November 2022

Microservice architecture (MSA) is an emerging architectural style as an innovative approach that is growing in quality over time. Microservices are endorsed by various researchers to shatter the issues and limitations encountered by the use of aging approaches for monolithic legacy architecture styles. Nonetheless, there exists no state of the research exhaustive study on migration to MSA from monolithic architecture. MSA has made the need to design the development methods of software and styles of architectures that satisfy these demands. The design of software architecture is the ongoing rise of MSA to address the independent deployment, scalability, and maintenance requirements. In this article, a systematic mapping study (SMS) was performed, including the literature on the migration approaches published between 2010 and 2021 to evaluate the contemporary state of the art and practice of software architecting. This study outlines the awareness and importance of MSA. Seventy‐three studies were finally selected in this SMS. The following perspectives of this study are publication trends, main venues, the focus of research, migration approaches, migration challenges, successful factors after migration, and the potential for industrial adoption. We synthesize the data and give a summary of the state of the art. This study also provides future research directions and applications for adopting microservices.
Clinical characteristics and prognosis of cystic degeneration in retroperitoneal schwannoma: A retrospective study of 79 patients
Authors: Xiao Jianchun , Cai Lizhu , Pu Jun , Liu Wei , Jia Congwei , He Xiaodong
Published: November 2022

Background and Purpose

Diagnosis of retroperitoneal schwannoma (RS), especially cystic RS, is frequently missed or delayed owing to its rarity, location, nonspecific symptoms, and similarities with other tumors on various imaging modalities. This study aimed to determine associations between clinical, radiological, and histopathologic features and outcome.

Materials and Methods

Seventy‐nine patients with pathologically confirmed RS who underwent tumor resection between June 2010 and June 2020 were retrospectively reviewed and analyzed. Patients were stratified into three groups according to degree of tumoral cystic degeneration.

Results

Cystic degeneration was significantly associated with multiple foci (p = 0.025), calcification (p = 0.012), and hemorrhage (p = 0.000), but not size (p = 0.08), high Ki‐67 (p = 0.094), malignancy (p = 0.115; prevalence of cystic degeneration in the benign and malignant groups were 53.9% vs 100%), rough margin (p = 0.162), or irregular shape (p = 0.369). Malignant RS was significantly associated with multiple lymph nodes enlargement (p = 0.034). Tumor size, margins, shape, or/and multiplicity did not significantly differ between benign and malignant tumors. No recurrence occurred in patients with benign RS (mean follow‐up, 45 months). All malignant tumors recurred; mean time to recurrence was 11.4 months (mean follow‐up, 33 months).

Conclusion

Since RS is misdiagnosed mostly as malignancy and diagnosis is often delayed, a suspicion is necessary for diagnosis when atypical features are present. In RS, cystic degeneration was not associated with tumor size, Ki‐67, or malignancy; however, it was significantly associated with multiple foci, calcification, and hemorrhage. Cystic degeneration and related factors are useful for the diagnosis of RS. Malignant RS should be considered when a mass involves multiple lymph nodes. Margins, morphology, and size are not associated with malignancy. Pathological tumor type, tumor location, and adjacent anatomic structures are associated with outcome.
Serum glycomic profile as a predictive biomarker of recurrence in patients with differentiated thyroid cancer
Authors: Kudelka Matthew R. , Lasanajak Yi , Smith David F. , Song Xuezheng , Hossain Mohammad S. , Owonikoko Taofeek K.
Published: November 2022

Purpose

Thyroid cancer recurrence following curative thyroidectomy is associated with increased morbidity and mortality, but current surveillance strategies are inadequate for early detection. Prior studies indicate that tissue glycosylation is altered in thyroid cancer, but the utility of serum glycosylation in thyroid cancer surveillance remains unexplored. We therefore assessed the potential utility of altered serum glycomic profile as a tumor‐specific target for disease surveillance in recurrent thyroid cancer.

Experimental design

We employed banked serum samples from patients with recurrent thyroid cancer post thyroidectomy and healthy controls. N‐glycans were enzymatically released from serum glycoproteins, labeled via permethylation, and analyzed by MALDI‐TOF mass spectrometry. Global level and specific subtypes of glycan structures were compared between patients and controls.

Results

We evaluated 28 independent samples from 13 patients with cancer recurrence and 15 healthy controls. Global features of glycosylation, including N‐glycan class and terminal glycan modifications were similar between groups, but three of 35 individual glycans showed significant differences. The three glycans were biosynthetically related biantennary core fucosylated N‐glycans that only varied by the degree of galactosylation (G0F, G1F, and G2F; G: galactose, F: fucose). The ratio of G0F:G1F that captures reduced galactosylation was observed in patients samples but not in healthy controls (p = 0.004) and predicted thyroid cancer recurrence (AUC = 0.82, CI 95% = 0.64–0.99).

Conclusions

Altered N‐glycomic profile was associated with thyroid cancer recurrence. This serum‐based biomarker would be useful as an effective surveillance tool to improve the care and prognosis of thyroid cancer after prospective validation.
Delayed tracheal necrosis presenting with stridor: A rare complication of surgery for differentiated thyroid cancer
Authors: Keditsu Keduovinuo , Dandekar Mitali , Yhome Khriesatalie , Keditsu Thejavinuo
Published: November 2022

Tracheal necrosis (TN) is a rare life‐threatening complication of thyroidectomy, generally diagnosed in the early postoperative period with neck swelling or subcutaneous emphysema. Late presentation with stridor has not been reported till date. We present a case of TN three weeks after surgery with stridor, managed with sternohyoid muscle cover.
A case report of two obstructive sleep apnea patients with cervical spine abnormalities and relevant literature review
Authors: Sun Anrong , Fang Rui , Luo Huiping
Published: November 2022

Obstructive sleep apnea (OSA) combined with cervical spine anatomy abnormalities could be an underestimated clinical problem. Here are two cases of this kind reported to draw attention to this issue.
Tophaceous gout of the nose in a male FMR1 premutation carrier
Authors: Tang Si Jie , Giri Shanthi , Pahlavan Nima , Han Sophia H. , Santos Ellery R. , Espinal Glenda , Aishworiya Ramkumar , Schneider Andrea , Hessl David , Rivera Susan M. , Hagerman Randi J.
Published: November 2022

Premutation alleles with 55–200 CGG repeats in FMR1 can lead to fragile X‐associated tremor/ataxia syndrome (FXTAS). In this case study, we report uncontrolled gout in a 68‐year‐old male with FXTAS with multiple sites of involvement including a rare gouty tophus in the nasal region.
Recovery of diabetes insipidus after Chiari malformation decompression: A rare manifestation of Chiari malformation
Authors: Roohollahi Faramarz , Iranmehr Arad , Mousavi Seyed Taher , Hajiabadi Mohamadreza
Published: November 2022

This paper aims to introduce a patient with Chiari type 1 malformation presented with upper extremity pain and diabetes insipidus. After laboratory examinations, we confirmed our case's central diabetes insipidus diagnosis. The patient has undergone posterior fossa decompression, tonsilopexy, and duraplasty. After 6 months of follow‐up, pain and diabetes insipidus were improved. We introduced a rare presentation of Chiari malformation in this article.
Transcolonic misplacement as a rare complication associated with PEG tube
Authors: Kozyk Marko , Strubchevska Kateryna , Batke Mihaela
Published: November 2022

PEG tube placement is a relatively safe procedure; however, complications sometimes occur. Our article will allow readers to visualize the uncommon complication of PEG ‐ a transcolonic misplacement.
The spectrum of cutaneous polyarteritis nodosa. A case report of two contrasting cases and review of the literature
Authors: Liang Ian , Hamid Mariya , Sebaratnam Deshan , Manolios Nicholas
Published: November 2022

Cutaneous polyarteritis nodosa is a rare neutrophilic vasculitis. We present two cases that reflect the gamut of this disorder including one case whose delayed diagnosis led to permanent nerve deficit and scarring.
Mucinous breast carcinoma with neuroendocrine differentiation: Case report
Authors: Limaiem Faten , Bouraoui Saadia
Published: November 2022

Mucinous carcinoma of the breast is rare representing 2% of all breast carcinomas. It can be classified as either a pure or a mixed type. Pure mucinous breast carcinoma has a less aggressive behavior compared with mixed breast mucinous carcinoma. The latter shows frequent neuroendocrine differentiation.
Pulmonary aspergilloma with prominent oxalate deposition
Authors: Limaiem Faten , Blibech Hana , Bouhajja Leila , Ben Farhat Leila , Louzir Bechir
Published: November 2022

Some Aspergillus species produce oxalic acid, which reacts with tissue calcium or blood to precipitate calcium oxalate. Oxalate crystals can induce lung and kidney damage. The presence of oxalate crystals can suggest the diagnosis of aspergillosis, even when Aspergillus hyphae are absent on microscopic slides.
High‐performance and wide relative humidity passive evaporative cooling utilizing atmospheric water
Authors: Wang Guang , Li Yang , Qiu Huihe , Yan He , Zhou Yanguang
Published: November 2022

Global warming and increased living standards have rapidly increased the demand for cooling systems. Meeting this demand in less economically developed areas is highly challenging due to a lack of electricity. In this paper, we have demonstrated a high‐performance and wide relative humidity (RH) solar‐driven evaporative cooling strategy that uses only atmospheric water. Developed here for the first time, we designed a metal–organic framework (MOF‐801) based composite with a high‐performance atmospheric water absorption across a wide range of RH. The as‐synthesized composite can adsorb atmospheric water up to ~22% (~80%) of its weight at an RH@28% (~70%). Our demonstration has shown that the corresponding cooling powers range from 136 to 344 W/m2 in a wide range of RH and solar intensities, and the passive cooling temperature is up to 14°C lower than the device's reference counterpart. Our study thus proposes a solar‐driven cooling coating with high cooling powers across a wide range of RH based on an as‐synthesized composite, which pinpoints a pathway to replace traditional compression‐based cooling systems (e.g., air conditioners) and which will also have a significant impact in future global energy consumption.
Novel field observations of coral reef fishes feeding on epiphytic and epizoic organisms associated with the allelopathic seaweed Galaxaura divaricata
Authors: Nieder Carolin , Liao Chen‐Pan , Lee Chen‐Lu , Clements Kendall D. , Liu Shao‐Lun
Published: November 2022

In degraded coral reef ecosystems, allelopathic macroalgae have received increasing attention from marine ecologists because their secondary metabolites (also known as allelochemicals) kill corals that grow adjacent to them and weaken the recovery of degraded reefs. One well‐known coral‐killing macroalga is the calcareous red seaweed Galaxaura. However, our knowledge of how coral reef fishes interact with allelopathic algae like Galaxaura is very limited. Here, we documented novel observations of feeding interactions of 17 species of coral reef fishes (herbivorous and carnivorous) with the filamentous Galaxaura divaricata on degraded lagoon patch reefs in Dongsha Atoll (South China Sea). Video analyses showed that territorial farming damselfishes (i.e., Dischistodus perspicillatus, D. prosopotaenia, Hemiglyphidodon plagiometopon, Pomacentrus grammorhynchus, P. adelus, and Neoglyphidodon nigroris) and juvenile parrotfishes (Scarus schlegeli, S. ghobban, S. rivulatus, and Chlorurus spilurus) likely used G. divaricata as a feeding substratum. Further, microscopic analyses revealed that the filamentous surface of G. divaricata harbored a wealth of epiphytic microalgae, such as filamentous cyanobacteria (i.e., Leptolyngbya, Lyngbya, Rivularia, Oscillatoria, and Stigonema), diatoms (i.e., Synedra, Nitzschia, Mastogloia, and Pleurosigma), and filamentous red algae (i.e., Heterosiphonia), suggesting that these fishes targeted the nutrient‐rich microscopic epiphytes rather than the nutrient‐poor host. Juvenile benthic carnivores (i.e., Labridae, Parupeneus multifasciatus, and Meiacanthus grammistes) form feeding assemblages with roving parrotfishes to feed on small invertebrates (i.e., amphipods, copepods, isopods, gastropods, and polychaetes) associated with G. divaricata. Given that coral reef fishes appear to target the epiphytes associated with Galaxaura rather than the alga itself, these observations thus substantiate the threat posed by the overgrowth of G. divaricata to coral recovery in degraded reef systems due to the lack of natural grazers.
Population genomic analyses support sympatric origins of parapatric morphs in a salamander
Authors: Buckingham Emily , Streicher Jeffrey W. , Fisher‐Reid M. Caitlin , Jezkova Tereza , Wiens John J.
Published: November 2022

In numerous clades, divergent sister species have largely non‐overlapping geographic ranges. This pattern presumably arises because species diverged in allopatry or parapatry, prior to a subsequent contact. Here, we provide population‐genomic evidence for the opposite scenario: previously sympatric ecotypes that have spatially separated into divergent monomorphic populations over large geographic scales (reverse sympatric scenario). We analyzed a North American salamander (Plethodon cinereus) with two color morphs that are broadly sympatric: striped (redback) and unstriped (leadback). Sympatric morphs can show considerable divergence in other traits, and many Plethodon species are fixed for a single morph. Long Island (New York) is unusual in having many pure redback and leadback populations that are spatially separated, with pure redback populations in the west and pure leadbacks in the east. Previous work showed that these pure‐morph populations were genetically, morphologically, and ecologically divergent. Here, we performed a coalescent‐based analysis of new data from 88,696 single‐nucleotide polymorphisms to address the origins of these populations. This analysis strongly supports the monophyly of Long Island populations and their subsequent divergence into pure redback and pure leadback populations. Taken together, these results suggest that the formerly sympatric mainland morphs separated into parapatric populations on Long Island, reversing the conventional speciation scenario.
Gaussian process forecasts Pseudogymnoascus destructans will cover coterminous United States by 2030
Authors: Wiens Ashton M. , Thogmartin Wayne E.
Published: November 2022

White‐nose syndrome has been decimating populations of several bat species since its first occurrence in the Northeastern United States in the winter 2006–2007. The spread of the disease has been monitored across the continent through the collaboration of many organizations. Inferring the rate of spread of the disease and predicting its arrival at new locations is critical when assessing the current and predicting the future status and trends of bat species. We developed a model of disease spread that simultaneously achieves high‐predictive performance, computational efficiency, and interpretability. We modeled white‐nose syndrome spread using Gaussian process variations to infer the spread rate of the disease front, identify areas of anomalous time of arrival, and provide future forecasts of the expected time of arrival throughout North America. Cross‐validation of model predictive performance identified a stationary Gaussian process without an additional residual error process as the best‐supported model. Results indicated that white‐nose syndrome is likely to spread throughout the entire continental United States by 2030. These annually updatable model predictions will be useful in determining the horizon over which disease management actions must take place as well as in status and trend assessments of disease‐affected bats.
Research status of the effects of natural oligosaccharides on glucose metabolism
Authors: Zhang Minjiao , Chen Yaobin , Chen Ruoxin , Wen Yuxi , Huang Qihui , Liu Yuanyuan , Zhao Chao
Published: November 2022

Diabetes is a common and frequently occurring endocrine and metabolic disease characterized by hyperglycemia with genetic tendency. At present, the drugs for diabetes include metformin, glimepiride, and acarbose. Although these drugs are effective, long‐term usage will produce secondary symptoms, such as Cushing's syndrome, limb hypertrophy, and even the risk of hypoglycemia. Many natural products have been found to treat diabetes, among which oligosaccharides are the most valuable. Oligosaccharides are low‐level oligosaccharides formed by the linkage of 2–10 monosaccharides through glycosidic bonds. Common oligosaccharides include chitosan oligosaccharides, xylooligosaccharides, konjac glucomannan, and brown algae oligosaccharides. It has the effects of reducing blood glucose, blood pressure, antioxidant, anti‐inflammatory, immune regulation, antiallergy, promoting the growth of bifidobacteria, and improving body health. With the continuous exploration of the medicinal value of natural oligosaccharides, more and more attention has been paid to their research. This review introduces some representative oligosaccharides with hypoglycemic effects, including their structural characteristics and hypoglycemic mechanism, as well as the application status and future development trend of oligosaccharides.
Effectiveness of online‐based cognitive intervention in community‐dwelling older adults with cognitive dysfunction: A systematic review and meta‐analysis
Authors: Chae Hee Jae , Lee Seon Heui
Published: November 2022

Background

Mild cognitive impairment (MCI) or mild dementia imposes a substantial burden on patients, families, and social systems. For MCI or mild dementia patient, cognitive training is required to prevent progression to dementia. With advances in digital health, cognitive interventions using information and communication technology (ICT) have become essential for maintaining independence and functioning in dementia patients.

Objectives

This study aimed to examine the effectiveness of an ICT‐based cognitive intervention in community‐dwelling older adults with MCI or mild dementia.

Methods

A literature search was performed in four databases: Ovid‐Medline, Ovid‐EMBASE, Cochrane Library, and CINAHL. We selected studies published up to April 15, 2021, on topics related to cognitive interventions using ICT in older adults with MCI or mild dementia.

Results

Forty‐four studies were included in the analysis. Our meta‐analysis showed that ICT‐based cognitive interventions significantly improved the Mini‐Mental State Examination score in the intervention group compared with that in the control group. Additionally, cognitive training using ICT was significantly effective for a period of more than 30 min, more than 6 weeks, and multi‐domain content. Moreover, a significant reduction in depression was found in the intervention group compared with that in the control group.

Conclusions

ICT‐based cognitive intervention had a positive effect on cognitive function, depression, and quality of life in older adults with MCI or mild dementia. Application of ICT‐based cognitive training to community‐dwelling older adults with MCI or mild dementia should be expanded, and nurses should play a pivotal role in mediating between these older adults.