bluuebunny/crossref_metadata_2025 huggingface dataset:
Current judgments regarding COVID-19 vaccination in patients with autoimmune inflammatory rheumatic diseases
Authors: Muravyov Yu.V.
Published: October 2021

The author reviews the current attitudes to vaccination against COVID-19 in patients with autoimmune inflammatory rheumatic diseases. Most experts admit theneed in vaccination, although data on its effectiveness and safety in patients with autoimmune inflammatory rheumatic diseases are limited, since such patients were not enrolled in phase I-III clinical trials. Vaccination is a cornerstone in the fight against the COVID-19 pandemic, althogh it cannot completely prevent SARS-CoV-2 infection. Therefore, vaccinated patients with autoimmune inflammatory rheumatic diseases should adhere to all measures that reduce the risk of infection, including wearing a mask, hand hygiene and social distancing.
Overview of Health Program Innovation “Fun For Mom”
Authors: Labiba Akila , Ainy Asmaripa
Published: October 2021

Maternal and child health is an important concern for all nations in the world including Indonesia. “Fun For Mom” is an innovation program at Sako Public Health Center in Palembang for increasing the knowledge of mothers regarding breastfeeding practice, complementary feeding, and maternal health during pregnancy and breastfeeding period.  This study describes the Fun for Mom program at Sako Public Health Center in Palembang.  This was a qualitative study that involved the analysis of data collected from in-depth interviews, documents review, and observations to describe the Fun for Mom program using the RE-AIM framework at Sako Public Health Center in Palembang. The purposive sampling technique has been applied and twelve interviews were conducted with a Head of Sako Public Health Center, a Program Manager, two Program Implementers, three Cadres, and five Program Participants. RE-AIM framework is a multi-attribute model with five dimensions: reach, effectiveness, adoption, implementation, and maintenance. According to this framework, the findings illustrated that around ten pregnant or breastfeeding mothers participated in each activity session. Exclusive breastfeeding increased after a year of its implementation from 2017 to 2018. Mothers easily understand the information given because of the use of game media in this program. All information is conveyed in simple language and can be applied in daily childcare. Health operational assistance (it is called BOK) is used to fund this program. Other financial supports are needed for the sustainability of the program. The Fun for Mom program is feasible as a community empowerment effort in a health center setting and can be developed further.
Tensile Strength of Cement-Treated Champlain Sea Clay: An Experimental and Numerical Study
Authors: Yang Kun
Published: October 2021

The deep soil mixing method is becoming increasingly popular in the treatment of problematic soils in Canada. Champlain Sea clay, found throughout the St. Laurence River basin from Ontario to Quebec, is well-known for its high compressibility and a sudden loss of its shear strength due to disturbance. The tensile strength of a stabilized soil is an important design parameter for structures, such as embankments and retaining walls. Currently, there is no study available on the tensile strength of cement-treated Champlain Sea clay. This study is to address this knowledge gap by using indirect tensile strength testing approaches, such as the Brazilian tensile test and unconfined penetration test. General use cement was selected for mixing with clay. The tensile strength results of cement-treated clay were compared and correlated with its unconfined compressive

strength to establish a relationship. According to this study, the tensile strength of cement-treated Champlain Sea clay was approximately 6 % of its unconfined compressive strength. The Brazilian tensile strength is recommended for future studies over the unconfined penetration test due to its reliability and consistency in the test results. A numerical simulation using Abaqus CAE was also performed on the behavior of a Brazilian tensile testing sample during loading. A fair agreement was observed between experimental and numerical simulation results up to crack initialization
Structural Behaviour Of Reinforced High-Performance Concrete Joints In Frames Subjected To Lateral Cyclic Loading
Authors: Abdulmajeed Ahmed Monjid
Published: October 2021

This project involves experimental and theoretical investigations on the structural behavior of different reinforced beam-column frame specimens made of different concrete materials and reinforcement configurations subjected to cyclic lateral loading to failure. This research is intended to develop high performance self-consolidating concrete (SCC) frames with Engineered Cementitious Composite (ECC) and Ultra-High-Performance Concrete (UHPC) joints with better seismic resistance and load carrying capacity as alternatives to conventional concrete frames. Four ECC and UHPC jointed shear and flexure critical SCC frames were tested and their performance was compared based on hysteretic load-deformation response, rebar/concrete strain development, cracking characteristics, stiffness degradation, energy absorption and failure modes. Comparison between code-based and experimental strength capacities is also conducted. The ECC jointed frames illustrated higher ductility, energy absorbing capacity and durability compared to their UHPC counterparts.
Becoming A Holistic Social Worker: An Autoethnography
Authors: Lam Sue
Published: October 2021

This research project is an autoethnography about my journey in becoming a holistic social worker. The theoretical framework includes critical race feminism, Asian feminism, and yin yang theory. The literature review finds social workers are integrating alternative healing practices in their professional work. The research methods are the process and product of writing the autoethnography. The research question is: what persons, situations, and experiences were influential in my becoming a holistic social worker? The findings indicate the influencing factors: family environment, learning kung fu and Chinese medicine, social justice activities at church, healing professionals, working in mental health field, training in counselling and mental health, and holistic social workers. The discussions indicate white supremacy, patriarchy, capitalism, and cultural appropriation had negative impacts on my life and presented opportunities for resistance.
TRANSLATING MOCHTAR LUBIS’S SHORT STORY “KULI KONTRAK” INTO ENGLISH: A NOVICE TRANSLATOR’S AUTOETHNOGRAPHY
Authors: Dewi Novita
Published: October 2021

This article is of reflection category exploring the common mistakes often occur in translating Indonesian literary texts into English by a non-native speaker of English. It argues that translation of literary texts is meticulous as it should involve interpretation and fluency in both source and target languages as well as creativity in order that the translated texts communicate equally well. It is the communicative power of translation that makes this undertaking of language transfer miraculous. Applying sufficient principles in translation and creative writing method, this article exemplifies the translation process of Mochtar Lubis’s short story “Kuli Kontrak” into “The Contract Coolies” that appears in the Your Story page of California-based Dalang Publishing bi-lingual website. Autoethnography is the method used in reporting the results. Three main problems that ensue in the Indonesian-English translation of this short story include (1) the concept of time, (2) the non-idiomatic use of body-parts, and (3) the unnecessary use of object construction/ passive voice that often do not translate well in English. By tackling these problems, the English reader may hopefully obtain the meaning-message of the short story as closely as possible to that acquired by Indonesian readers.
A REFORMA TRABALHISTA DE 2017 E AS RELAÇÕES DE TRABALHO DO CONTRATO INTERMITENTE: A RÁPIDA DIFUSÃO DO PRECARIADO FORMAL
Authors: Carvalhal Marcelo Dornelis , Araújo Marcela Oliveira , Molon Adams Henrique
Published: October 2021

O artigo analisa as implicações da adoção do trabalho intermitente com a Reforma trabalhista de 2017 e as consequências para o mercado de trabalho. A análise dos dados da CAGED em 2018 e 2019 revela a rápida difusão da contratação de trabalho intermitente, isso ocorreu tanto em termos setoriais/ocupacionais, quanto municipais. Ainda que tenha pequena participação percentual em relação ao total de contratações no período, apresenta uso crescente em todo o período analisado e significa uma flexibilização das formas de contratação com significativa precarização da relação de trabalho
SEMEANDO A RESISTÊNCIA CAMPONESA: UMA ANÁLISE DA COOPERAÇÃO NA HISTÓRIA DOS BANCOS COMUNITÁRIOS DE SEMENTES NO SEMIÁRIDO DE ALAGOAS
Authors: Santos Flávio Dos , Campos Christiane Senhorinha Soares
Published: October 2021

No semiárido alagoano camponeses realizam desde a década de 1980 um trabalho coletivo voltado para a preservação das sementes crioulas, prática que a partir de 1990 passou a ser conduzida pela Cooperativa dos Pequenos Produtores Agrícolas dos Bancos Comunitários de Sementes, criada para organizar e expandir o trabalho de guarda das cultivares crioulas nas comunidades rurais. Frente a essa realidade grupos do agronegócio, a fim de suplantar os organismos crioulos, vem disseminando produtos híbridos e transgênicos no Semiárido do Alagoas, colocando assim novos desafios para a luta campesina. Ancorado em uma abordagem quantitativa-quantitativa, o artigo objetiva analisar o papel do trabalho cooperativo para a salvaguarda das sementes crioulas no contexto do Semiárido alagoano, de modo a evidenciar a relevância dessa pratica para a reprodução e resistência camponesa.
COOPERAÇÃO E SOLIDARIEDADE PARA O DESENVOLVIMENTO SUSTENTÁVEL NO TERRITÓRIO DA BAÍA DA ILHA GRANDE/RJ, BRASIL
Authors: Ramos Diná Andrade Lima Ramos , Villela Lamounier Erthal , Nascimento Carlos Alberto Sarmento do
Published: October 2021

O artigo analisou iniciativas das comunidades rurais e pesqueiras no Território Rural da Baía da Ilha Grande-RJ, estruturadas em ações cooperadas e solidárias, objetivando a inclusão socioprodutiva. A metodologia agregou pesquisas oriundas de múltiplas atividades de um programa de extensão universitário. Assim sendo, as informações foram coletadas por intermédio de observação participante, reuniões do colegiado BIG, diários de pesquisa, entrevistas semiestruturadas, oficinas remotas e debates em lives. A pesquisa revelou que as articulações das referidas comunidades quando elaboradas dialogicamente com as redes entre instituições de ensino, pesquisa, extensão, assistência técnica, representações do poder público e mercado, podem ser promissoras nas ações pluriativas de inclusão socioprodutiva, proporcionando resultados inovadores, emancipatórios e territorialmente sustentáveis como é o caso do mercado popular, feiras, associações, cooperativas e consórcios.
ALGORITHM FOR DETERMINATION OF RELIABILITY INDICATOR OF GAS GENERATOR OF HYDROGEN STORAGE AND SUPPLY SYSTEM
Authors: Abramov Y. , Kryvtsova V. , Mikhailyuk A.
Published: October 2021

An algorithm for determining one of the indicators of reliability of the main element of the hydrogen storage and supply system – a gas generator has been developed. Such an algorithm is an integral part of the general algorithm to ensure the required level of fire safety of hydrogen storage and supply systems. The algorithm involves the implementation of several stages. At the first stage, using the expression for the amplitude-frequency characteristic of the gas generator, the functional dependences for its time constants are obtained. These functional dependencies include the values of the transmission coefficient and amplitude-frequency characteristics, which are determined at three a priori set values of frequency. In the second stage, the amplitude-frequency characteristic of the gas generator is determined. For this purpose, an array of data is used, which characterizes the reaction of the gas generator to the test effect in the form of an abrupt change in the area of its outlet. The amplitude-frequency characteristic of the gas generator is determined numerically, and its parameters are the increase in the pressure in the cavity of the gas generator and the time interval at which this increase is determined. The Kotelnikov-Nyquist-Shannon theorem is used to determine this time interval. At the third stage, the probability of the values of the time constants of the gas generator outside the tolerance zone is determined. For this purpose, models of gas generator time constants and their metrological characteristics are used. In the fourth stage, the probability of failure of the gas generator is determined, for which the information of the previous stage is used. At the last stage, the algorithm for determining the probability of failure of the gas generator of the storage and supply system of hydrogen, which is given in verbal form.
INTERCONNECTION BETWEEN GLOBAL SUPPLY CHAINS AND INDUSTRY
Authors:   Market Economy Institute of RAS, Bryntsev Alexander N. , Bykova M.A. ,   ANO VO "Humanitarian Institute"
Published: October 2021

In the article, the authors consider the issues of the relationship between global supply chains and industrial production of semiconductors in modern conditions. Particular attention is paid to the applied value of the application of artificial intelligence technologies in industry in the light of the growth of global competition. Their specific features, strengths and weaknesses are shown. A brief macroeconomic analysis of the development of markets for robotics, the automotive industry, high-tech products, as well as modern regulations on the eve of a new technological order is given.
Reseña del libro "Entornos Personales de Aprendizaje: claves para el ecosistema educativo en red"
Authors: Departamento de Formación y Actualización Académica
Published: October 2021

Linda Castañeda y Jordi Adell son los editores de la primera publicación del libro digital centrado en el Entorno Personal de Aprendizaje –PLE por sus siglas en inglés–, el cual es definido por los autores como “el conjunto de herramientas, fuentes de información, conexiones y actividades que cada persona utiliza de forma asidua para aprender” (2013, p. 16). Asimismo, consideran al entorno como un “entramado de conexiones sociales y de fuentes básicas” (Castañeda y Adell, 2013, p. 11), inherentes a la construcción del propio aprendizaje.
Ambalajlı Et ve Et Ürünleri ile Süt ve Süt Ürünlerinin ‘Beslenme Bildiriminin’ Değerlendirilmesi
Authors: Konak Hilal
Published: October 2021

Amaç: Bu çalışma ambalajlı et ve süt ürünlerinin ambalajları üzerinde zorunlu beslenme bildiriminin varlığını ve bu bildirimin 26 Ocak 2017 tarihli Resmi Gazetede yayımlanan ‘Türk Gıda Kodeksi Gıda Etiketleme ve Tüketicileri Bilgilendirme Yönetmeliği’ kapsamında belirtilen ‘Beslenme Bildirimine’ uygunluğunu değerlendirmek amacıyla gerçekleştirilmiştir.

Gereç ve yöntem: İstanbul ilinde faaliyet gösteren zincir marketlerde satışa sunulan, 70 farklı markanın toplam 362 ambalajlı et ve süt ürünlerinin besin etiket bilgileri Ocak ve Mart 2018 tarihleri arasında toplanmıştır. Veri toplama işlemi, sözlü olarak izin alınan marketler ziyaret edilerek ve ambalajlı besinlerin fotoğrafları çekilip kaydedilerek tamamlanmış ve yönetmeliğe uygunluğu değerlendirilmiştir.

Bulgular: Besin etiket bilgileri değerlendirilen 362 ambalajlı besinlerin %94.2’sinde ambalajda ‘beslenme bildiriminin bulunduğu saptanmıştır. Ürünlerin %75.1’inde beslenme bildiriminin ambalajın arka yüzünde yer aldığı ve çoğunlukla (%88.3) Türkçe olarak bildirildiği belirlenmiştir. Zorunlu beslenme bildirimi kapsamında bulunan enerji değeri (%93.5), yağ (%93.3), karbonhidrat (%93.5) ve protein (%93.5) bildirim oranlarının yüksek olduğu, ancak doymuş yağ (%30.5), şekerler (%27.6) ve tuz (%25.2) bildirim oranlarının düşük olduğu belirlenmiştir.

Sonuç: Bu araştırma verilerine dayanarak Türkiye’de besin etiketlerinin tüketicileri sağlıklı besin seçimine yönlendirebilecek ve daha anlaşılır olacak şekilde yeniden düzenlenmesi önerilebilir. Besin etiketlerinin yönetmeliğe uygun olması, toplum sağlığının korunması ve geliştirilmesi için büyük önem taşımaktadır. Bu doğrultuda tüketiciler için önyüz etiketleme, sağlıklı besin seçimini kolaylaştırmak için önerilmektedir.
Comparación de los modelos de planificación tradicional y ATR para resistencia aeróbica en el atletismo
Authors: Madariaga Ortiz Ronny Rafael , Gutiérrez Gómez Catalina
Published: October 2021

El objetivo del presente artículo es determinar las diferencias que se presentan en la planificación de modelo tradicional a los bloques de la acumulación, transformación y realización (ATR), con respecto al desarrollo de la resistencia en atletas de categoría de iniciación. Se analizó el uso de los dos modelos de planificación tradicional frente a los bloques del ATR, desde el aspecto metodológico para determinar el modelo de entrenamiento más empleado para atleta en categoría élite; teniendo en cuenta el aspecto físico de la resistencia como eje fundamental del estudio. La metodología de estudio realizada fue una revisión bibliográfica de texto enfocados a la parte metodológica y la preparación de la resistencia en entrenamiento deportivo, en la que se determinó qué aspecto tienen en cuenta los autores para desarrollar la resistencia. Los resultados obtenidos demuestran una gran variedad de procesos de trabajos, para el cual se pude establecer o realizar la unificación de diferentes puntos de vista de los autores para así establecer procesos acordes. Podemos concluir que si nos decidimos por un método acorde al desarrollo de la resistencia en atleta de iniciación tomaríamos el modelo tradicional esto se debe al aumento de las cargas, proceso que debe ser progresivo, por lo cual no permite lesiones o sobrecargas y sobre todo tiene como prioridad el trabajo en jóvenes en etapa de iniciación.
ЗДОРОВ’Я І ЗДОРОВИЙ СПОСІБ ЖИТТЯ СТУДЕНТІВ ЯК ЧИННИКИ ФОРМУВАННЯ ДУХОВНОЇ КУЛЬТУРИ ОСОБИСТОСТІ
Authors: Пристинський В. М. , Пристинська Т. М. , Зайцев В. О. , Майдіков Ю. Л.
Published: October 2021

У статті обґрунтовано доцільність впровадження в навчально-виховний процес студентів педагогічних технологій, які сприяють розвитку компетентностей щодо відповідального ставлення до здоров’я і здорового способу життя. Визначено критерії (мотиваційно-цільовий, когнітивно-дієвий, рефлексивно-особистісний), показники та рівні сформованості таких компетентностей як чинників духовної культури особистості. Експериментальна перевірка ефективності впливу педагогічних технологій на формування відповідального ставлення студентів до здоров’я і здорового способу життя здійснювались на базі кафедр теоретичних, методичних основ фізичного виховання і реабілітації; фізичної терапії, фізичного виховання і біології; науково-дослідної лабораторії духовного й фізичного виховання дітей та учнівської молоді ДВНЗ «Донбаський державний педагогічний університет» (Слов’янськ), а також фізичної реабілітації Національного університету «Чернігівська політехніка» (Чернігів). До експериментально-дослідної роботи було залучено 25 студентів другого курсу факультету фізичного виховання; 42 студенти першого і другого курсів факультету психології, економіки й управління та 47 студентів першого і другого курсів філологічного факультету. Встановлено позитивну динаміку формування відповідального ставлення до здоров’я і здорового способу життя у студентів експериментальних груп, яка характеризується зростанням високого рівня на 19,2 % (в контрольних групах – на 2,3 %) та зниженням низького рівня на 31,7 % (в контрольних групах – на 3,1 %). Доведено, що впроваджені педагогічні технології, а також критерії та показники розвитку відповідального ставлення студентів до здоров’я і здорового способу життя є ефективними чинниками формування духовної культури особистості.
ФОРМУВАННЯ ПРОФЕСІЙНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНЬОГО ВЧИТЕЛЯ МУЗИЧНОГО МИСТЕЦТВА У ПРОЦЕСІ ФАХОВОГО НАВЧАННЯ
Authors: Сбітнєва Л. М.
Published: October 2021

У статті розкрито сутність професійної підготовки майбутнього вчителя музичного мистецтва до роботи у сучасній школі. Наголошено, що у ХХI столітті важливим завданням ЗВО виступає професійна підготовка майбутніх вчителів музичного мистецтва, які будуть здатні впливати на розвиток музичної культури підростаючого покоління, збереження й збагачення національно-культурних традицій українського народу.

Зазначено, що інноваційні процеси, що відбуваються в галузі української освіти, виявляють істотні протиріччя між потребами сучасного світу та реальним станом підготовки майбутніх учителів музичного мистецтва до роботи в загальноосвітній школі. Професійна компетентність є необхідною у музично-педагогічній діяльності майбутнього вчителя музичного мистецтва, який буде соціально та психологічно адаптований та здатний до постійного професійного росту.

Доведено, що проблемам компетентнісного підходу у фаховому навчанні, питанням змісту і структури компетенцій присвячено праці багатьох відомих вчених.

Обґрунтовано, що  концепція цілісної системи підготовки вчителя музики включає в себе єдність загальнопедагогічної (знання педагогіки, психології, культурології) і спеціальної підготовки (музично-теоретичні знання, володіння музичним інструментом, співацьким голосом, навичками ансамблевого виконання, диригентською технікою, методикою музичного навчання і виховання).

Доведено, що професійна діяльність вчителя музичного мистецтва є багатоаспектною і включає в себе  виконавський, педагогічний і управлінський аспекти, вона є неможливою без вокальної, інструментальної і диригентсько-хорової підготовки.

Автор вважає, що професійну компетентність майбутнього вчителя музичного мистецтва слід розуміти як інтегративну якість, яка виявляється в: умінні використовувати свої знання в розвитку музичного сприймання, розвитку музичних здібностей учнів; здійснювати художньо-педагогічний аналіз творів, володіти методиками розвитку дитячого голосу та знаннями про особливості організаційної роботи у дитячих музичних колективах; розуміти сутність позакласної музично-естетичної роботи.
JESUS CHRIST: THE PARAMOUNT EXEMPLAR OF SPIRITUAL WELL-BEING
Authors: Фішер Джон В.
Published: October 2021

Instead of directly addressing the theme of this conference, which begins with ‘Problems of spiritual awakening of a personality’, what is included herein is a potential solution to the problem. This paper is written from the author’s personal perspective, as an evangelical Christian. It provides material for each person to ponder and for reflection on well-being. The Bible, and particularly the Gospel of John, is interpreted using the Four Domains Model of Spiritual Health/Well-Being to support the claim that Jesus Christ is the paramount exemplar of spiritual well-being. This model proposes that spiritual well-being is reflected in the quality of relationships that each person has with self, others, nature and God. As Christ showed how to live in harmony in these four domains, which is the ultimate of spiritual well-being, his life provides a foundation for us to emulate. Christ not only showed us how to live in harmony with God, nature, others and self; he provided the way. Each person has the choice, whether or not to follow in his footsteps to achieve the ultimate of spiritual well-being – eternal life with God. If parents, pastoral carers, pedagogues, physicians, politicians and the populace, including pupils, cared for themselves and others in the same manner as would Jesus Christ, what a wonderful world it would be. We would not only be spiritually aware but fully awake.
SPIRITUAL AWAKENING AMONG ANGLICAN CLERGY DURING THE PANDEMIC: EXPLORING THE EFFECTS OF PERSONAL FACTORS, PERSONALITY, CHURCH ORIENTATION, AND RELIGIOUS PRACTICE
Authors: Френсіс Леслі Джон , Віллідж Ендрю , Льюїс Крістофер Алан
Published: October 2021

The experience under consideration in this study is rooted in the Covid-19 pandemic as crystalised in the events in England and Wales between late March 2020 and July 2020, when the Government imposed a national lockdown and when the Church of England imposed a national lock-up on its churches. The religious tradition under consideration is the Christian theological response to human disease and suffering. For considerable periods during the Covid-19 pandemic, England and Wales were in lockdown and churches were closed. Church services were live-streamed or pre-recorded for internet-savvy members to access online at home. For some clergy the pandemic may have been a challenge to faith, while for others the experience of the pandemic may have been an opportunity to re-kindle faith. A sample of 1,050 Anglican clergy serving in England completed an online survey including the newly developed Lewis Index of Spiritual Awakening (LISA) alongside a range of other measures. The Lewis Index of Spiritual Awakening (LISA) was found to have good psychometric properties. The data demonstrated that considerably more Anglican clergy experienced a sense of spiritual awakening during the pandemic than experienced a spiritual decline. The data also demonstrated that higher levels of spiritual awakening among Anglican clergy were associated with two factors, one psychological and one ecclesial. Clergy who report higher scores of spiritual awakening are more emotionally stable, associated with one of the two wings of the Anglican Church (Evangelical or Anglo-Catholic) rather than with the middle way of Broad Church, and influenced by the Charismatic Movement.
El modelo “e business” como estrategia de negocios para el sector textil
Authors: Caisa Yucailla Elias David , Padilla Martínez Mario Patricio , Quispe Otacoma Ana Lucia , Cunalata Escobar José Miguel
Published: October 2021

Introducción. En el caso de estudio Escotex, es una empresa que se dedica a la elaboración de bordados computarizados, fue fundada con la iniciativa de servir a la ciudadanía ambateña empezando con tres máquinas bordadoras, en la actualidad Escotex, cuenta con alrededor de 17 operarios, 12 máquinas bordadoras y con alrededor de 20 clientes fijos, también se ha emprendido en nuevas líneas como la confección de ropa infantil y ropa industrial de trabajo, con el fin de ampliar su negocio y contribuir a la matriz productiva del país, la presente investigación se ha enfocado en realizar un amplio análisis del entorno interno y externo de la empresa. Objetivo. Establecer estrategias de negocios e-business que permitan mejorar la demanda de los productos e incrementar las ventas para la empresa. Metodología. Se realizó una Investigación exploratoria, con el propósito de definir el problema identificado y los aspectos importantes de los fenómenos que inciden en él. Se aplicó la investigación descriptiva detallando las características importantes del sector textil de la provincia de Tungurahua, mediante la recolección de información para identificar la problemática y cumplir con los objetivos señalados. Para ello se realizará lo siguiente: observación directa, mediante la aplicación de encuesta, y también un análisis de prospectiva estratégica que permita incrementar las ventas de la empresa. Resultados. Los datos arrojados por la encuesta aplicada a los clientes de la empresa Escotex indican que es importante corregir aspectos como la publicidad y promoción como parte inherente del éxito, puesto que estos son factores que la mayoría de los clientes consideran como falencias y que se deben mejorar. Así la propuesta resultante de la investigación se direccionó para identificar y diseñar publicidad y promoción para la empresa Escotex, utilizando canales virtuales dirigido a los clientes actuales y potenciales. Conclusión. La aplicación del modelo e-business genera diferentes actividades encaminadas a facilitar la rotación y venta del producto de la forma esperada por la propietaria de la empresa Escotex.
La teoría de la complejidad y su influencia en el proceso de enseñanza-aprendizaje de los estudiantes de educación superior: Una sistematización teórica
Authors: Prieto-López Yeimer , Ayala-Pazmiño Mario , Baquerizo-Álava Verónica
Published: October 2021

Este artículo relaciona aspectos del pensamiento teórico y epistemológico de Edgar Morin con el aprendizaje y la producción científica de los alumnos matriculados en un Máster de Gestión Educativa. El objetivo del trabajo es analizar las responsabilidades cognitivas de los profesores universitarios y la formación del pensamiento complejo, considerado un elemento esencial de la educación. Asimismo, el artículo también utiliza el proceso de aprendizaje realizado por los estudiantes matriculados en un máster de Gestión Educativa para comprender la aplicación de la teoría de la complejidad de Morin en el desarrollo cognitivo dentro de los programas de posgrado.
Distribusi Cacing Trematoda Saluran Pencernaan Katak Dari Berbabgai Lokasi Persawahan Di Kabupaten Lombok Timur
Authors: Wolagole Kristian , Kholik Kholik , Supriadi Supriadi , Oktaviana Dina
Published: October 2021

Trematode worms have been found in various types of frogs which cause disease in frogs or toads can be a reservoir for these worms. Lombok Island has many rice fields which are habitat for frogs. Frogs that live in this environment allow direct contact with various types of Trematodes. The purpose of this study was to determine the type and distribution of Trematoda worms found in the digestive tract of frogs in the rice fields of East Lombok Regency. A cross-sectional survey study using purposive sampling methods on frogs in three rice fields in East Lombok Regency was carried out in February 2020. Worms were collected from the digestive tract of frogs and fixed with 70% warm alcohol, cleaned with alcohol, and examined under a microscope. A total of 64 frog samples were taken in three rice fields, East Lombok Regency. A sample examination was carried out  at the Equin Clinical Center Skill laboratory Faculty of Veterinary Medicine of Mandalika University of Education. The results showed that Mesocoelium spp was distributed among frogs in three rice fields in East Lombok Regency, with a prevalence of 45% in Pringgabaya Village, 50% in Suele Village, and 53.57% in Tanjung Teros Village.
Deteksi Cacing Nematoda Pada Ayamkampung (Gallus domesticus) Di Desa Bagikpayung Kecamatan Suralaga Kabupaten Lombok Timur
Authors: Kurnia Febi , Atma Candra Dwi , Ningtyas Novarina Sulsia Ista'In , Janah Maratun
Published: October 2021

Ayam kampung merupakan salah satu unggas yang memiliki cukup banyak manfaat untuk kehidupan manusia sebagai bahan pangan. Infeksi cacing nematoda memiliki angka kematian yang rendah, namun memiliki efek langsung pada produktivitas dan akan menggangu kesehatan masyarakat. Telah dilakukan penelitian pada Ayam Buras di Desa Bagik Payung Kecamatan Suralaga Kabupaten Lombok Timur dengan tujuan untuk mendeteksi cacing nematoda pada Ayam Kampung. Sampel yang diambil sebanyak 10 feses Ayam Buras dan diperiksa dengan metode natif dan apung dilaboratorium Equine Clinical Skills Center (CSC) Fakultas Kedokteran Hewan Universitas Pendidikan Mandalika Mataram kemudian diidentifikasi berdasarkan morfologinya. Hasil didapatkan 3 sampel positif terinfeksi cacing golongan nematoda. Hasil deteksi jenis cacing nematoda yang menginfeksi Ayam Buras yaitu jenis Capillaria sp. Berdasarkan penelitian ini dapat disimpulkan bahwa Ayam Buras di Desa Bagik Payung Kecamatan Suralaga Kabupaten Lombok Timur terinfeksi endoparasit cacing.
Penerapan Metode AHP Berbasis Web Dalam Pemilihan Dosen Terbaik
Authors: Hendraputra Surya
Published: October 2021

Penelitian ini bertujuan untuk mengetahui dan menentukan dosen terbaik pada Politeknik ganesha Medan. Selama ini Politeknik Ganesha Medan masih menggunakan sistem penilaian secara manual dengan mengisi form penilian yang dilakukan oleh mahasiswa kepada dosen. Dalam penilaian tersebut masih menggunakan sistem manual dengan mengisi form mempergunakan pulpen dan kertas serta perangkat komputer yang dipakai masih terbilang belum teraplikasi secara otomatis, dalam hal tersebut menyebabkan keterlambatan dalam perhitungan serta menetapkan dosen terbaik dari beberapa kandidat yang ada. Aplikasi penilaian dosen terbaik dengan metode AHP berbasis web pada Politeknik Ganesha Medan dibuat dengan mengumpulkan data informasi yang diperlukan oleh peneliti untuk menunjang proses penelitian agar dapat menjadi gambaran mengenai situasi, kondisi serta kejadian yang berjalan pada masa ini. Dalam merancang aplikasi peneliti menggunakan flowchart dan flow diagram sebagai alur perancangan aplikasi, dengan harapan peneliti dapat memudahkan dan membantu dalam merancang sistem yang sedang dibuat pada kegiatan Politeknik Ganesha Medan dalam melakukan penilaian dosen terbaik. Dengan menggunakan Metode AHP ini, peneliti meyakini bahwa hasil dari penelitian ini, dianggap sudah sangat mendekati dengan kondisi yang sebenarnya. Dalam penelitian ini, terdapat 4 kandidat dosen yang dinilai. Dan menghasilkan 1 dosen terbaik yang bernama bapak Romindo
Update on Biologics in Treatment of Chronic Rhinosinusitis With Nasal Polyposis
Authors: Kim Su-Jong , Moon Jee Won , Lee Heung-Man
Published: October 2021

Chronic rhinosinusitis is a common chronic inflammatory condition of sinonasal cavities and occurs with or without nasal polyps. Uncontrolled chronic rhinosinusitis with nasal polyp (CRSwNP) has a negative impact on an individual’s quality of life. Many studies have been conducted for novel treatments targeting type 2 cytokines involved in CRSwNP such as interleukin (IL)-4, IL-5, IL-13 and immunoglobulin E. Biologics have recently been proven to improve the nasal symptoms of CRSwNP and reduce the need for systemic glucocorticosteroids. Recently dupilumab, omalizumab and mepolizumab were approved by Food and Drug Administration for CRSwNP, and other biologics are under investigation. Large-scale and longterm clinical trials are needed for therapeutic effectiveness, and several questions remain regarding patient selection, treatment algorithm, and cost-effectiveness. Nevertheless, emerging biologics may offer a new therapeutic option for uncontrolled CRSwNP.
Application of Artificial Intelligence-Based Risk Management in Banking
Authors: Permatasari Mutiara Dewi , Salsabyla Nisa Aurelya , Nurfitri Nurfitri
Published: October 2021

Penelitian ini bertujuan untuk mengetahui pengaruh Artifial Intelligence (AI) di sektor perbankan dan peran AI dalam manajemen risiko perbankan. Penelitian ini merupakan penelitian kualitatif dengan menggunakan pendekatan studi pustaka, yang diperoleh dari beberapa sumber literatur berupa jurnal ilmiah, artikel, penelitian terdahulu maupun e-book terkait yang dimuat di media dengan kredibilitas jelas secara online. Data dianalisis menggunakan analisis deskriptif berkaitan dengan penerapan artifial intelligence pada manajemen risiko di bank secara menyeluruh, kemudian menyimpulkan hasil-hasil atas penelitian-penelitian tersebut. Penelitian ini menemukan bahwa perbankan termasuk ke dalam bidang yang dituntut untuk dapat menerapkan AI dengan maksimal, dikarenakan adanya persaingan yang sangat kompetitif. Selain itu, kami juga menemukan bahwa artificial intelligence yang berperan sebagai risk management, benar- benar dapat membantu lembaga keuangan perbankan untuk mengatasi dan meminimalisir permasalahan yang terjadi, sehingga dapat mengoptimalkan pendapatan dan mengurangi adanya kerugian. Saran bagi penelitian selanjutnya yaitu dapat melakukan pada industri lain yang terkait, dengan isi pembahasan yang lebih mendalam.
Experimental pharmacokinetics of the GZK-111 drug preparation exhibiting neuroprotective activity
Authors: Podolko A. L. , Bochkov P. O. , Shevchenko R. V. , Litvin A. A. , Kolyvanov G. B. , Zherdev V. P.
Published: October 2021

We studied the pharmacokinetics of a drug preparation, ethyl ester of N-phenylacetyl-glycyl-L-proline, exhibiting neuroprotective activity and its metabolite cyclo-L-prolylglycine in rat blood plasma after a single intravenous administration at a dose of 20 mg/kg. The metabolite was found to circulate in the systemic bloodstream of animals twice as long as the ethyl ester of N-phenylacetyl-glycyl-L-proline, with its plasma concentrations being 50–70 times higher than those of the parent compound.
Maintenance and breeding of transgenic mouse strains at the scientific center of biomedical technologies of the FMBA of Russia
Authors: Petrova N. V. , Skripkina M. M.
Published: October 2021

In this article, we analyze the specifics of health monitoring and maintenance of transgenic mouse strains. A method for keeping animals in laboratory conditions is discussed, the criteria for inbred crossing of homozygous transgenic mice lines are characterized. The obtained data can be useful for the staff of vivaria in maintaining the transgenic line of mice.
Gender sensitive research in adult education: Looking back and looking forward to explore what is and what is missing in the research agenda
Authors: Ostrouch-Kamińska Joanna , Vieira Cristina C. , Merrill Barbara
Published: October 2021

Despite legislation, policies and practice, and while some progress has been made in many countries, there are still no countries who have achieved a hundred per cent gender equality (Gender Equality Index, EIGE, 2019). Over the years this has included several supranational agreements and mandatory regulations signed by countries such as the Convention of the Elimination of all Forms of Discrimination against Women (CEDAW, 1979), the Platform of Beijing (1995), the Istanbul Convention (2011), and more recently the UN Sustainable Development Goals (2015), among others. The failure of these initiatives indicate that gender inequality, discrimination and prejudice suffered by women are embedded in structural unequal power relations. The ultimate goal of the ‘gender mainstreaming principle’ is the integration of a gender perspective into the preparation, design, implementation, monitoring and evaluation policies, regulatory measures and spending programmes (including research ones), with a view to promoting gender equality between women and men, and combating discrimination.
Barriers To Discipleship In The Mandarin-Based Churches
Authors: Sugiarto Thio Donald
Published: October 2021

Discipleship today has again become a principal concern, was greeted with positive and implemented practically in the Lord's church, including the church-based mandarin which will be the object of research journal. However the fact is, after going through a preliminary study in the form of informal conversations with some of the Servants of the Lord and of the Assembly representing some church-based mandarin, the authors noticed that even though discipleship approved by a majority of the Servant of the Lord as an important thing that must be done, however there are still many of the church who have not done it in a concrete way in real life. Seminar after seminar and training for the sake of training has been held, in great demand and was followed by thousands of people from dozens of even hundreds of church, however only a handful of the church has been run in real time and sustainable.

      Considering the importance of discipleship which is the great mission of Jesus, not just an option or optional, even though there are many aspects that can be examined in the subject of discipleship, the authors will focus his research on the obstacles that may arise in the implementation of discipleship practically in the church, in particular that based on mandarin. Therefore, the authors wanted to examine further, the first about the essence of discipleship itself, and continued with research on the constraints, obstacles and challenges that make this discipleship can't be implemented in churches, in particular that based mandarin where the author to worship and serve.
Interrupting the Conversation: Implications for Crosstalk Between Viral and Bacterial Infections in the Asthmatic Airway
Authors: Ackland Jodie , Watson Alastair , Wilkinson Tom M. A. , Staples Karl J.
Published: October 2021

Asthma is a heterogeneous, chronic respiratory disease affecting 300 million people and is thought to be driven by different inflammatory endotypes influenced by a myriad of genetic and environmental factors. The complexity of asthma has rendered it challenging to develop preventative and disease modifying therapies and it remains an unmet clinical need. Whilst many factors have been implicated in asthma pathogenesis and exacerbations, evidence indicates a prominent role for respiratory viruses. However, advances in culture-independent detection methods and extensive microbial profiling of the lung, have also demonstrated a role for respiratory bacteria in asthma. In particular, airway colonization by the Proteobacteria species Nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) is associated with increased risk of developing recurrent wheeze and asthma in early life, poor clinical outcomes in established adult asthma and the development of more severe inflammatory phenotypes. Furthermore, emerging evidence indicates that bacterial-viral interactions may influence exacerbation risk and disease severity, highlighting the need to consider the impact chronic airway colonization by respiratory bacteria has on influencing host responses to viral infection. In this review, we first outline the currently understood role of viral and bacterial infections in precipitating asthma exacerbations and discuss the underappreciated potential impact of bacteria-virus crosstalk in modulating host responses. We discuss the mechanisms by which early life infection may predispose to asthma development. Finally, we consider how infection and persistent airway colonization may drive different asthma phenotypes, with a view to identifying pathophysiological mechanisms that may prove tractable to new treatment modalities.
Development of a Bone-Mimetic 3D Printed Ti6Al4V Scaffold to Enhance Osteoblast-Derived Extracellular Vesicles’ Therapeutic Efficacy for Bone Regeneration
Authors: Man Kenny , Brunet Mathieu Y. , Louth Sophie , Robinson Thomas E. , Fernandez-Rhodes Maria , Williams Soraya , Federici Angelica S. , Davies Owen G. , Hoey David A. , Cox Sophie C.
Published: October 2021

Extracellular Vesicles (EVs) are considered promising nanoscale therapeutics for bone regeneration. To date, EVs are typically procured from cells on 2D tissue culture plastic, an artificial environment that limits cell growth and does not replicate in situ biochemical or biophysical conditions. This study investigated the potential of 3D printed titanium scaffolds coated with hydroxyapatite to promote the therapeutic efficacy of osteoblast-derived EVs. Ti6Al4V titanium scaffolds with different pore sizes (500 and 1000 µm) and shapes (square and triangle) were fabricated by selective laser melting. A bone-mimetic nano-needle hydroxyapatite (nnHA) coating was then applied. EVs were procured from scaffold-cultured osteoblasts over 2 weeks and vesicle concentration was determined using the CD63 ELISA. Osteogenic differentiation of human bone marrow stromal cells (hBMSCs) following treatment with primed EVs was evaluated by assessing alkaline phosphatase activity, collagen production and calcium deposition. Triangle pore scaffolds significantly increased osteoblast mineralisation (1.5-fold) when compared to square architectures (P ≤ 0.001). Interestingly, EV yield was also significantly enhanced on these higher permeability structures (P ≤ 0.001), in particular (2.2-fold) for the larger pore structures (1000 µm). Furthermore osteoblast-derived EVs isolated from triangular pore scaffolds significantly increased hBMSCs mineralisation when compared to EVs acquired from square pore scaffolds (1.7-fold) and 2D culture (2.2-fold) (P ≤ 0.001). Coating with nnHA significantly improved osteoblast mineralisation (>2.6-fold) and EV production (4.5-fold) when compared to uncoated scaffolds (P ≤ 0.001). Together, these findings demonstrate the potential of harnessing bone-mimetic culture platforms to enhance the production of pro-regenerative EVs as an acellular tool for bone repair.
Identification and Functional Analysis of G Protein-Coupled Receptors in 20-Hydroxyecdysone Signaling From the Helicoverpa armigera Genome
Authors: Li Yan-Li , Li Yan-Xue , Wang Xiao-Pei , Kang Xin-Le , Guo Ke-Qin , Dong Du-Juan , Wang Jin-Xing , Zhao Xiao-Fan
Published: October 2021

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors in animals and humans, which transmit various signals from the extracellular environment into cells. Studies have reported that several GPCRs transmit the same signal; however, the mechanism is unclear. In the present study, we identified all 122 classical GPCRs from the genome of Helicoverpa armigera, a lepidopteran pest species. Twenty-four GPCRs were identified as upregulated at the metamorphic stage by comparing the transcriptomes of the midgut at the metamorphic and feeding stages. Nine of them were confirmed to be upregulated at the metamorphic stage. RNA interference in larvae revealed the prolactin-releasing peptide receptor (PRRPR), smoothened (SMO), adipokinetic hormone receptor (AKHR), and 5-hydroxytryptamine receptor (HTR) are involved in steroid hormone 20-hydroxyecdysone (20E)-promoted pupation. Frizzled 7 (FZD7) is involved in growth, while tachykinin-like peptides receptor 86C (TKR86C) had no effect on growth and pupation. Via these GPCRs, 20E regulated the expression of different genes, respectively, including Pten (encoding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase), FoxO (encoding forkhead box O), BrZ7 (encoding broad isoform Z7), Kr-h1 (encoding Krüppel homolog 1), Wnt (encoding Wingless/Integrated) and cMyc, with hormone receptor 3 (HHR3) as their common regulating target. PRRPR was identified as a new 20E cell membrane receptor using a binding assay. These data suggested that 20E, via different GPCRs, regulates different gene expression to integrate growth and development.
Neuroimmune Evasion of Zika Virus to Facilitate Viral Pathogenesis
Authors: Xie Xiaochun , Zeng Jianxiong
Published: October 2021

Zika virus (ZIKV), which preferentially targets neural stem and progenitor cells (NSCs) especially in developing brain, is causally associated with fetal microcephaly, intrauterine retardation, and other congenital malformations in humans. However, there are, so far, no effective drugs and vaccines against ZIKV epidemics, warranting an enhanced understanding of ZIKV biology. Immune response is essential for neuronal cells to combat viral invasion. In turn, neurotropic ZIKV has developed a complex strategy of neuroimmune evasion to facilitate viral pathogenesis, especially developmental impairment in embryonic brain. Here, we review not only overall knowledge of ZIKV-related immune responses, but also current advances in our understanding of immune evasion in ZIKV infection. We also review several specific mechanisms underlying ZIKV protein-mediated immune evasion for viral pathogenesis.