bluuebunny/crossref_metadata_2025 huggingface dataset:
ERAS for Free Fibula Flap Surgery: Effects on Postoperative Recovery and Complications
Authors: Hsiao Wei-Ling , Wu Yao-Cheng , Tai Hao-Chih
Published: April 2023

This study aimed to evaluate the effects of the enhanced recovery after surgery (ERAS) program on postoperative recovery of patients who underwent free fibula flap surgery.This retrospective study enrolled 188 patients who underwent free fibula flap surgery between January 2018 and December 2022; after propensity score matching, the ERAS and non-ERAS groups included 36 patients each. The primary outcome was the length of intensive care unit stay; the secondary outcomes were flap complications, unplanned reoperation, 30-day readmission, postoperative ventilator use length, surgical site infections, lower-limb comorbidities, and morbidity parameters.There were no significant differences in the demographic characteristics of the patients. However, the ERAS group showed lower length of intensive care unit stay (ERAS vs non-ERAS: 8.66 ± 3.90 days vs. 11.64 ± 5.42 days, P = 0.027) and post-operative ventilator use days (ERAS vs non-ERAS: 1.08 ± 0.28 days vs. 2.03 ± 1.05 days, P < 0.001). Other secondary outcomes were not significantly different between the two groups. Additionally, patients in the ERAS group had lower postoperative morbidity parameters, such as postoperative nausea, vomiting, urinary tract infections, and pulmonary complications (P = 0.044).The ERAS program could be beneficial and safe for patients undergoing free fibula flap surgery, thereby improving their recovery and not increasing flap complications and 30-day readmission.
A Closer Look at the Time Course of Bodily Responses to Awe Experiences
Authors: Takano Ryota , Nomura Michio
Published: April 2023

The structure and function of awe have been examined by focusing on the average level of outcomes during awe experiences. In the present study, we tested the psychophysiological process of experiencing awe, focusing on time-series changes in skin conductance responses (SCRs), a moment-by-moment measure of sympathetic nervous responses, and pupil diameter, which is dilated or constricted through the (para)sympathetic nervous system. The responses were measured through an experiment where 77 Japanese university students watched emotional (awe, amusement, or neutral) videos while moving a joystick when they felt supernatural agency or non-agency, examining the underlying psychological processes. We found that experiencing awe was associated with frequent and steep changes in SCRs and frequent changes in pupil diameter. The joystick inclination, the perceptions of the supernatural, was kept at a high level from the start to the end of awe experiences. These results may reflect the psychophysiological processes of awe: the fluctuation of the sympathetic nervous system might underlie awe-specific experiences. Our findings shed new light on the mechanisms of the body-mind interaction in awe experiences. However, this study’s findings are limited in terms of generalizability and heterogeneity given that psychophysiological processes of awe might be different depending on demographic characteristics.
Post-Bragg Peak keV-Secondary Electron Radiolysis Revealed by Track-Ends Imaging of High-Energy Protons.
Authors: Audouin Julien , Hofverberg Petter , Ngono-Ravache Yvette , Desorgher Laurent , Baldacchino Gerard
Published: April 2023

Upstream of the efficiency of proton or carbon ion beams in cancer therapy, and to optimize hadrontherapy results, we analysed the chemistry of Fricke solutions in track-end of 64-MeV protons and 1.14-GeV carbon ions. An original optical setup is designed to determine the primary track-segment yields along the last millimetres of the ion track with a sub-millimetre resolution. The Fe3+-yield falls in the Bragg peak to (4.9±0.4)×10-7mol/J and 1.9×10-7mol/J, under protons and carbon ions respectively. Beyond the proton Bragg peak, a yield recovery is observed over 1 mm. It is attributed to the proton beam straggling. Since a dose rate effect is ruled out in this region, keV secondary electrons are hypothesized to produce this intermediate LET effect. They might also provide DNA lesions during proton exposure, potentially at the origin of delayed radio-induced carcinogenesis.
Construction and analysis of a hepatocellular carcinoma prognostic model based on cuproptosis-related lncRNAs
Authors: Shi Dandan , Yang Fangming , Zhao Qing , Zhao Qiang , Yuan Changwei , Zhang Chuanlei , Wang Xinting , Chen Xiaoqi , Chen Xinju
Published: April 2023

Objective To screen cuproptosis-relatedlncRNAs and establish a prognostic model of cuproptosis-related lncRNAs in hepatocellular carcinoma (HCC).
Methods Perl and R languages were used to collate the HCC transcriptome and clinical data downloaded from the TCGA database. Cuproptosis-related lncRNAs were obtained through co-expression analysis, and the total samples were randomly divided into the Train group and the Test group. Univariate Cox regression analysis, LASSO regression and multivariate Cox analysis were used to analyze the data of Train group to establish the prognostic model of cuproptosis-related lncRNAs. The accuracy of the model was verified by principal component analysis (PCA), ROC curve, and independent prognostic analysis. GO and KEGG enrichment analysis, tumor mutation burden correlation analysis, immunocorrelation analysis and drug sensitivity analysis were conducted in depth.
Results Co-expression analysis showed 258 cuproptosis-related lncRNAs, univariate Cox regression analysis showed 31 lncRNAs were correlated with HCC prognosis, and multivariate Cox analysis showed 5 lncRNAs involved in model construction. They are LINC00426, AL590705.3, SPRY4-AS1, AL031985.3, and AC002091.2. Validation analysis showed that the survival of patients in the low-risk group was significantly better than that in the high-risk group, and the model could be used as an independent prognostic factor for HCC. Immunocorrelation analysis showed that patients in the high and low-risk groups significantly differed in immune-related functions and immune-related therapy, which was consistent with the GO and KEGG enrichment analysis results. Tumor mutation burden correlation and drug sensitivity analysis can further guide the diagnosis and treatment of HCC patients.
Conclusion The HCC prognostic model constructed by 5 cuproptosis-related lncRNAs has high accuracy and has a certain reference value for clinical diagnosis and treatment of HCC patients.
Long non-coding RNA AC005479.2 plays a critical role in papillary thyroid carcinoma
Authors: Liang Xinke , Liu Shenghui , Wang Pengfei , Huo Shengnan , Li Jianying , Hou Qingtian
Published: April 2023

Background
Papillary thyroid carcinoma (PTC) is the most common subtype of differentiated thyroid malignancy, with increasing incidence. The long non-coding RNA (lncRNA) AC005479.2 has been shown to play a role in the tumorigenesis and development of multiple cancers, although its role in PTC remains unclear. Therefore, we aimed to identify the expression, function, and mechanisms of AC005479.2 in PTC.
Methods
The data were downloaded from TCGA database. The expression of AC005479.2 in PTC samples was determined by R package “limma” and RT-qPCR, and weighted gene co-expression network analysis (WGCNA) was used to explore the association between AC005479.2 and PTC. Through genetic enrichment analysis (GSEA) set of AC005479.2, potential function and molecular mechanism were discussed. Receiver operating characteristic (ROC) curve analysis was used to determine the performance of AC005479.2. Univariate and multivariate Cox regression analyses were used to analyze the effects on the prognosis of patients with PTC.
Results
The results showed that AC005479.2 was up-regulated in TCGA-PTC and PTC samples. Eleven PTC-related modules were obtained from the WGCNA, and AC005479.2 was in the blue module, which had the strongest association with PTC. AC005479.2-related genes were obtained from the blue module, and GSEA-GO analysis of these genes was mainly enriched in aerobic respiration, lipid oxidation, and negative regulation of extrinsic apoptotic signaling pathway via death down, while KEGG analysis was mainly enriched in the MAPK, JAK-STAT, and NOTCH signaling pathways. Area under the ROC curve is 0.838, prompt AC005479.2 may be PTC diagnostic biomarkers. Univariate and multivariate Cox analyses indicated that AC005479.2 was an independent risk factor for the prognosis of patients with PTC.
Conclusion
AC005479.2 is up-regulated in PTC, where it may serve as a biomarker gene, providing an important basis for future research.
Enset (Enset ventricosum) Plant Disease and Pests Identification Using Image Processing and Deep Convolutional Neural Network.
Authors: Yigbeta Tesage , Meshesha Million , Bedaso Muktar
Published: April 2023

Enset is a monocarpic perennial crop which belongs to the Schistaminae order and the Musaceae family. Enset is a key food security crop in Southern Ethiopia, where almost 20 million people rely on it for survival. Plant leaf diseases and destructive pests are a major challenge in Enset production. This study looks into the use of deep learning to detect bacterial wilt disease and Enset mealybug pest, where data is obtained in small amounts and collected under minimally controlled conditions. We employed data augmentation to get over the limits of the dataset size. The proposed approach is divided into four stages. The initial part entails gathering healthy and diseased Enset images with the support of agricultural experts, from various farms and research institutes. Then image processing tasks, resizing and segmentation are applied on the collected dataset in order to get an enhanced (simpler) image and to extract region of interest from the dataset images. Finally, using the collected dataset, the created model is trained and evaluated, and it is compared to the state-of-the-art pre-trained convolutional neural network models: AlexNet, ResNet50, Inceptionv3, DenseNet201, VGG16 and EfficientNetB3. The proposed approach is implemented using google Collaboratory or "Colab" for short. To detect and classify Enset diseases, the model has an accuracy of 99.68% for training and 98.87% for testing.
Design and Implementation of Thermal Sensor Based Temperature Measuring Robot Using Arduino Uno
Authors: Arifuzzaman Md. , Shipon Md. Rezaur Rahman , Akhi Jannatul Afroj , Sejuti Shamima Yasmin , Rahman Md. Tareque , Khan Prof. Dr. Muhammad Abdul Goffar
Published: April 2023

This paper is about the “Thermal sensor based Temperature Measuring Robot” using Arduino Uno circuits. In this technology, Temperature Measuring Robot measured the temperature of the human body and the temperature of any object. The MLX90614 infrared thermometer is a contactless temperature sensor module for Arduino compatible device. An infrared thermometer works to measure the object temperature by the infrared radiation in the form of an electromagnetic wave through the light emitted on the object. MLX90614 is a powerful infrared sensing device with a very low noise amplifier with a 17 bit ADC. It utilizes non-contact temperature sensing to collect the temperature info without touching any surface of the object. The construction is equipped with many sensors. Hardware and software architecture and integration with Robot operating system is described in details. In the last part of the paper we presented the results of implemented measurement technologies and draw conclusions.
“For brevity, Fig. 5 only presents the results of …”: Visual-Textual Moves of Electronic Engineering Research Articles by Chinese and Native English Speaking Writers
Authors: Gao Sutong , Pramoolsook Issra
Published: April 2023

Visuals are essential components in achieving the communicative purpose of research articles (RAs). Besides, the fact that electronic engineering RAs (EERAs) contain a large number of visuals makes it worth investigating these essential components and their rhetorical functions. By adopting the multimodal move analysis framework of Moghaddasi et al. (2019), the present study explored visuals’ rhetorical functions through examination of the visual-textual moves (VTMs) in 24 EERAs composed by Chinese and Native English speaking writers. Comparisons of the visuals and VTMs in the two corpora were carried out for similarities and variations between the two writer groups. The findings showed that first, visuals in the Introduction (I) and the Methods (M) sections demonstrated mainly ontological function, while those in the Results and Discussion (RD) section played more of epistemological and argument functions. Secondly, more similarities, except for some subtle variations, were found between the two writer groups in terms of the employment of VTMs. The findings of VTMs, as well as their similarities and variations between Chinese and native English speaking writers, not only broaden RA genre knowledge for EE researchers and genre practitioners, but also give insights into academic writing instruction and material design for ESP and EAP practitioners.
Reduced vitamin D levels in diabetic retinopathy: cause or effect?
Authors: Zhuang Yong , Zhuang Zihao , Cai Qingyan , Hu Xin , Huang Huibin
Published: April 2023

Aims: Research suggests that vitamin Ddeficiency is associated with diabetic retinopathy (DR). Our study aimed to understand whether vitamin D deficiency is the cause of DR or whether people with DR have low vitamin D.
Methods: Participants with type 2 diabetes were recruited for this prospective observational clinical study and were divided into a diabetic group without retinopathy and a diabetic group with retinopathy, with additional healthy volunteers serving as controls. The differences in clinical characteristics between the three groups were compared. The incidence of DR in patients without retinopathy was then followed for one year. Follow-up participants were divided into subgroups based on whether DR occurred. Baseline data of subgroups were compared, and independent risk factors were analyzed.
Results: Vitamin D levels were generally low. Participants with DR had significantly lower vitamin D levels than those without retinopathy (P< 0.01). A comparison of the two subgroups revealed lower baseline vitamin D data in the new-DR subgroup than in the non-DR subgroup (P< 0.01). Vitamin D deficiency and elevated HbA1c levels were independent risk factors for DR (OR= 0.926, 95% CI: 0.867～0.990, P= 0.024; OR= 2.108, 95% CI: 1.540～2.883, P< 0.01). The limit of vitamin D measured using the ROC curve was 18.15 ng/mL, and the area under the ROC curve was 0.635 (95% CI: 0.559～0.706, P= 0.002).
Conclusions: Vitamin D levels were significantly reduced in those diagnosed with DR. At the same time, vitamin D deficiency may accelerate the onset of DR.
Stochastic process analysis enhancement via quantum system parameter estimation
Authors: Gautam Kumar
Published: April 2023

In this paper, we investigate a linear Ito stochastic differential equation in the vector space from every conceivable perspective. In this case, the potential vector describes the magnitude of the classical noise acting on a quantum system. This vector potential can be expressed as a linear function of its parameters, with Hermitian operators serving as its coefficients since its parameters are assumed to be unknown. To the second order of perturbation, the unitary evolution operator can be determined with the aid of a potential perturbation parameter. As for the second term, it is written as a double-iterated stochastic integral with respect to Brownian motion, while the first term is written as an Ito stochastic integral. When controlling quantum systems, noise from the environment can be a major hindrance; this technique can help. Improve the dependability and practicality of quantum technologies like computers by learning to detect and regulate noise. If the potential’s parameters are affected by noise, then their reliability is thought to decrease. We focus on the special case where the potential is a linear function of these parameters with Hermitian operators as the coefficients. To find the unitary evolution operator up to O(ε), we can write the O(ε) term as an ito stochastic integral with respect to Brownian motion, and the O(ε2) term as a doubly iterated stochastic integral with respect to Brownian motion.
Impact of Domestic Violence on the Parenting Styles of Men who were Child Victims in Uganda.
Authors: Arubuola Mary Anuoluwapo
Published: April 2023

The UNICEF (2008) declared domestic violence one of the most anti-human rights issue aswell as a global contemporary health issue. The effects of the issue transcend beyond the twoindividuals directly involved. It affects any other dependents in the environment, the justicesystem and the society. Despite it not being a recent concept, only recently did an increasingawareness about domestic violence create a research interest in the topic and its impacts.Increase in awareness led to increased research, however varying definitions of the termviolence as well as gender biased research which has most of the research being about femalevictims has created a limitation in the amount of information available on the topic. This studyassesses and analyses already existing literature on the impact of domestic violence on childvictims and explains a need to research on the possible effects that witnessing domesticviolence as children, especially boys, has on their parenting styles. A retrospective cohort studyis proposed to be carried out in Uganda to ascertain if the experiencing of domestic violenceas children does influence the parenting styles, especially the male gender.
Bioinformatics Analysis of Key Genes and miRNAs Associated with Small-cell Lung Cancer
Authors: Khan Imteyaz Ahmad , Sharma Srikant
Published: April 2023

Small-cell lung cancer (SCLC) is a type of lung cancer, accounting for approximately 15% of lung cancers. SCLC is significantly associated with early recurrence, metastasis, and poor prognosis, with a 2-year survival rate after therapy, which is <5%. The molecular mechanisms underlying the development of SCLC are not clear. In this study, we identified SCLC-specific biomarkers by evaluating the differential expression of mRNA and microRNA (miRNA) profiles in SCLC tissue compared with normal lung tissue. A non-coding RNA sequence dataset (GSE19945) and transcriptome sequencing dataset (GSE6044) were downloaded from the GEO database. We identified 445 DEGs (differentially expressed genes) and 128 DE-miRNAs (differentially expressed miRNAs) using the GEO2R tool of the GEO and R limma software package. Furthermore, using the KEGG database, we identified 15 enrichment pathways, mostly associated with DNA replication, cell cycle, and oocyte meiosis mismatch repair, and the GO function was considerably enriched for 26 items. To investigate the molecular processes of key signaling pathways and cellular activity in SCLC, we used Cytoscape software to construct protein-protein interaction (PPI) networks. Using miRNAWalk, we identified 598 target genes of the 1380 miRNAs and constructed miRNA target networks. In addition, we identified eighteen overlapping genes that are regulated by 28 different miRNAs. The identified hub genes are important because they may be used as biomarkers for prognosis, diagnosis, and therapeutic target for SCLC.
Diabetogenic Microbiome - A Review on the Microbes Involve in Diabetes
Authors: Barman Indrani , Talukdar Apurba , Hazarika Shrijona , Talukdar Nayan
Published: April 2023

Diabetes has emerged as a pandemic and has caused a great percentage of mortality all over the world according to the World Health Organization (WHO). This worldwide health issue has turned to be a major concern as it shares its role in the onset and progression of many other metabolic diseases along with it. Several factors that include microbes such as bacteria and viruses, diet, and lifestyle comes into play in the progression of this autoimmune disease. Studies done on humans and experimental animal models have provided a great deal of knowledge on how bacteria and viruses are involved in the pathogenesis of diabetes. Nevertheless, the need for more investigations is required to understand the relationship between the microbes and disease development. This review deals with the underlying reasons of diabetes Type I and Type II especially with respect to the microbes in the body and the subsequent changes caused through them.
Phytochemical Screening and Antibacterial Activities of Oroxylum indicum (Linn.): A Threatened Tree of India
Authors: Lama Rohini , Manjula B. L. , Kumbar Vijayalaxmi , Panda Asim , Singh Arvinder , Kumar Sanjeet , Marndi Sugimani
Published: April 2023

Oroxylum indicum belongs to the family Bignoniaceae. It is used as a traditional medicine from a very long time and because of over exploitation comes under threatened category. It is traditionally used against inflammation and bacterial infections. Keeping this in view, an attempt has been made to evaluate its pharmacological value through phytochemical analysis and antibacterial activities against four pathogenic bacteria. Results revealed that leaf and fruit extracts are rich in diverse types of bioactive compounds and showed inhibition potential against selected microbes. The present study highlights the importance of pharmacological potential of O indicum against antimicrobial resistance.
Effect of Prolonged Use of Face Masks in Dental Professionals during COVID-19
Authors: Neelam Singh , Natasha Gupta , Rana Apoorva , Singh Shradha
Published: April 2023

Objective: The study was undertaken to understand the long-term effect of using non-pharmaceutical intervention like face mask for protection against COVID-19. The dental professionals are at high risk as mostly all procedures generate aerosols and thus they were using the face masks with PPE for long hours. This study evaluated the various symptoms which were experienced by the professionals when the masks were worn for <4 h, 4 h, and >4 h. Methods: A cross-sectional and observational study was carried out online by circulating a Google form among dental professionals practicing in Delhi NCR Region. The form was circulated using social platform. The survey included MCQ questions enquiring about the symptoms that were experienced by professionals after using face masks. The data were assembled and analyzed using SPSS (Version 16, IBM). Results: The Google form was distributed to 150 professionals and we received responses from 99. Our study showed that the symptoms were more pronounced when the mask was worn for 4 h or >4 h. The symptoms such as sweating around mask, sore throat, difficulty in breathing, feeling of nasal discomfort, and other symptoms were seen around in 11.1% cases when worn <4 h whereas other symptoms were not presented at all during this time period. Conclusion: This study showed that whenever face masks were worn for 4 or more h, it leads to significant discomfort. This would, in turn, affect the efficiency of the face mask, breach the PPE protocol, and hamper the quality of work.
Use of Chatbot for Addressing Adolescent’s Queries on Sexual and Reproductive Health-related Issues – Findings from a Field Implementation in Madhya Pradesh, India
Authors: Prasad Rajnish Ranjan , Badgujar Shrutika
Published: April 2023

As per the Census of 2011, adolescent and young people (10–24 years of age) constitute around 30% of the India’s population. Young people face number of challenges in accessing information on sexual and reproductive health (SRH) due to associated taboos. To address these challenges, an initiative was launched to provide life skill-based education to the adolescent across 120 villages in two districts of Madhya Pradesh. After the program implementation for a year, it was observed that adolescents were not comfortable during the SRH sessions. Hence, after discussion with adolescents a chatbot was designed and launched. The chatbot had access to more than 9000 question and answers including audio and video materials. After 6 months, a brief assessment was undertaken with 2047 adolescent (boys - 1186 and girls - 861) to assess its relevance and usefulness. The concept of chatbot was appreciated by 93% of the respondents and they prefer it instead of having face-to-face conversation with counselor or health-care providers. About 90% respondents appreciated the fact that it is easily accessible, 87% respondents appreciated that it has comprehensive information and 86% respondents found chat messages appropriate. About 24% respondents were worried that as their family members may see their chats. About 38% respondents also expressed the need of making it multilingual and support some regional languages. Chatbot can be very powerful medium to address adolescent’s queries on SRH-related issues as it is easily accessible, and adolescent feel more comfortable. At the same time, it needs to be backed with quality service provision.
Insect Repellents: A Review on Available Options and Current Formulation Trends
Authors: Pawar Saylee Ashok , Kapadnis Mrunal , Dhikale Rupali , Jadhav Anil
Published: April 2023

A total of 164,103 dengue cases were recorded in 2021, compared to 205,243 cases in 2019. Since 2008, the case fatality rate has been fewer than 1%. The administration had reviewed the country’s worrisome dengue condition. Dengue cases have all surged dramatically around the world. One among the best way to avoid the bite of mosquito is to use repellents. The previous papers have primarily relied on herbal repellents or synthetic, formulation methods and thud has been unable to compile it in single paper with global forecast and recent products available in market. So, I tried to compile all this matter in this paper. In this review, a survey plants that have a repelling effect, synthetic agents (chemicals with insect repellent), a review of formulation trends, and a global forecast market and products available in the market were conducted.
A Case Study on Breathing Rehabilitation in a 32-year-old Male with Dysfunctional Breathing
Authors: Singh Avnika , Gulyani Latika , Singh Anshika , Raghav Sumit
Published: April 2023

Despite having a significant impact on the personal, psychological, and social dimensions of a person’s health, health professionals’ emphasis on the epidemiological, pathological, and physiological basis of the dysfunctional breathing, therefore, fails to provide patients with an appropriate treatment. Given the multifarious and psychophysiological nature of dysfunctional breathing, a holistic and multidimensional management would seem the most appropriate way to manage such a prevalent condition This case study presents a holistic approach to comprehensively manage dysfunctional breathing. That being the case, interventions for four key domains — biochemical aspects, biomechanical aspects, psychosocial aspects, and respiratory symptoms — were provided. It was obvious from the outcome findings that dysfunctional breathing can only be successfully understood by relating it to the person’s life experiences including their, beliefs, values, emotions, influences, and social relations.
Effects of Short-term Intensive Yoga Program on Yoga Instructors or Therapist
Authors: Pal Rameswar , Rai Priyanka , Rao Sobika , Basavaraddi Ishwar V.
Published: April 2023

Impacts of Yoga are recognizing day by day. Accordingly, the job has been created for Yoga Instructors and Therapist. Although many studies have already been published and elaborate the effects of Yogic practice on normal healthy population as well as disease population, effects of short-term intensive Yogic practice on Yoga Instructors or Therapist are rare. Yoga Instructors were randomly chosen from a 06 days intensive training course to find out the impacts of short-term intensive Yoga training on blood pressure (BP), muscle strength, flexibility body composition, and psychological parameters. BP decreased significantly. Body composition, muscle strength, and flexibility did not show any significant change. Exercise-induced efficiency increased significantly. This particular 06 day intensive Yoga program may relax mind and body, participants goes toward parasympathodominance as a result BP component reduced significantly. Short-term Yoga program may increase exercise induced efficiency in Yoga Instructors or Therapist. Short-term Yoga practices is beneficial for Yoga Instructors and Therapist in terms to reduce BP and enhance exercise-induced efficiency.
A Pain Management through Ayurveda (Viddha Karma) in Gridhrasi (Sciatica) – A Case Report
Authors: Singh Swati , Chaudhari Vaishali R. , Ganbote Prashant
Published: April 2023

Gridhrasi (Sciatica) is a musculoskeletal disorder in ayurveda, in which patient walks like gridha (vulture), So named as gridhrasi. In this disease, extreme and radiating pain occurs from the lower back to thighs and legs. In today’s era, vata vyadhi become so much common, not only old people but youngers also start becoming the patient of vata vyadhi. Here, one of them is Gridhrasi (Sciatica). In this article, I am presenting a case study on a 34-year-old patient with the complaints of Ruka (Pain), Toda (Pricking pain), and Stambha (Stiffness) start from Sphik (Buttock) and radiate toward Kati (Lumber region), Uru (Thighs), Janu (Knee joint), and Pada (legs) and left leg SLR positive was treated with ayurveda. Panchakarma is a group of various kind of therapies, which helps in the treatment in ayurveda. It has its own importance as it works on overall aspects of diseased as well as healthy person too. It does purification of body and gives nutrition too. Viddha karma is explained in Sushrut Samhita and it works very good in pain management as it helps in eradication of Avrodha (vata) [Obstruction] in ayurveda avrutta vata is the main cause of pain in Gridhrasi. According to Acharya Sushrut, the site of Viddha karma is 4 angula (finger) above and below the knee crease on the lateral aspect, but it also can be given at the site of the pain. This whole study was completed in 30 days, where Viddha karma was performed on every alternate day in first 7 days and then every 3rd day for 21 days.
Quality and Content of Online Information Related to “Immunity Boosting”
Authors: Shrivastava Anu , Agarwal Aparna , Jain Swati
Published: April 2023

In this era of “infodemic,” online health information has become a prime concern, and therefore, an analysis of studies on online health information, the reasons for which people seek online health information, its strengths and shortcomings, and the concept of E-health literacy has been done in this paper. Various tools to assess online health information and recent papers on assessment using DISCERN tool have been discussed. The concern for immunity boosting and its significance in the COVID era has grown manifold, especially for providers and consumers of health information. Online health information has become a vital part of healthcare in modern times; however, its quality seems to differ across domains. Online information on immunity boosting also seem to be misleading the people. This article provides an insight into the sphere of online health information and throws light over the hurdles that people come across face while retrieving health information online.
Assessment of Future Manpower Requirements in Public Healthcare of India and its Northeastern Region
Authors: Mawkhlieng Donald R. , Dhillon Preeti , Ladusingh L.
Published: April 2023

Health-care workforce planning is crucial for active healthcare provision and to achieve an improvement in population health. One of the major challenges in the quest for achieving the goals of the Universal Health Coverage is the shortage of skilled health workers which is a matter of concern for health planners. The paper attempts to project the future requirement of allopathic physician practicing in public sector for India and Northeast India using the health information data from the Datanet India (Indiastat). The projection of physician was done using the average doctor to physician ratio for the year 2004–2017 and population projection was derived using the average exponential growth rate. Study found that with the current trend, India and Northeast are still far from meeting the healthcare needs of the population and the shortage of allopathic physician in public sectors will continue to persist in future. Under the current scenario, India will have require close to 1.6 million public sector allopathic doctors in 2030 to keep up with the WHO standard population to physician ratio. Northeast India will need 0.05 million to achieve the same standard. It could be expected that public health workforce in India and Northeast will remain insufficient in the future and this may have serious implication to the poor and vulnerable section of the population and therefore calls for a need to have a strong build-up and development in Indian health-care system.
Dexmedetomidine:” Role in Pediatric Dentistry
Authors: Sangal Aayushi , Goswami Mousumi , Nangia Tanu , Khan Shumayla , Shivangani Shivangani , Tuli Shivya
Published: April 2023

A number of sedative agents have been in use in pediatric dentistry to gain a child’s cooperation with dental treatment. Dexmedetomidine is one such agent that was introduced as a sedative in the dental practice in 2005 due to a more stable respiratory drive and higher success rates in allowing pediatric dentists to carry out non-painful dental examinations and procedures compared to other sedatives such as chloral hydrate and midazolam. The most distinguishing feature of this sedative is its ability to produce a form of sedation that mimics natural sleep. The high safety margin of dexmedetomidine and its satisfactory sedative action makes it important for us to review its potential applications in pediatric dentistry.
Avaliação da posição do forame apical em caninos humanos
Authors: Carolina Cardamoni SALONSKI  , Elisa Mara de COSTA  , Helen de Lacerda LOPES  , Marili Doro DEONIZIO  , Vânia Portela Ditzel WESTPHALEN  , Ulisses Xavier da SILVA NETO  , Luiz Fernando FARINIUK
Published: April 2023

A variação da posição do forame apical, somada às estruturas radiopacasda região óssea, quase sempre dificulta sua identificação por meio doexame das radiografias, podendo alterar o prognóstico do tratamento.O objetivo deste trabalho foi avaliar visual e radiograficamente a posiçãodo forame e a mensuração quando este não se posicionar no ápice.Foram utilizados 100 caninos superiores monorradiculados. Após arealização do acesso endodôntico os dentes foram explorados com umalima tipo K # 10 até sua observação no forame. Em seguida o dente foiradiografado e realizaram-se as medidas com um paquímetro digitaltanto no dente como no raio X. Os resultados mostraram que 58% dosdentes apresentaram raízes curvas, e em 22% a curva era por vestibular.Na análise radiográfica verificou-se que em 64% o forame localizava-seno ápice; já visualmente apenas 44% encontrava-se no ápice. Com relaçãoà distância visual versus radiográfica constatou-se que em 43% dos casoshavia correspondência entre elas, enquanto em 12% dos casos a distânciaradiográfica foi três vezes superior à visual. Conclui-se com o presenteestudo que a visualização radiográfica do forame no ápice nem semprecondiz com a realidade, devendo-se levar em consideração oconhecimento anatômico durante o tratamento endodôntico.
Editorial
Authors: Adriane Cristina Kasprowicz
Published: April 2023

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Reabsorção radicular externa inflamatória: descrição de caso clínico utilizando pasta de hidróxido de cálcio
Authors: Roberta LAMPING  , Lilian Eiko MAEKAWA  , Sidnei MARCACCI  , Maria Renata Giazzi NASSRI
Published: April 2023

A ocorrência de reabsorção radicular externa pode estar ligada a umprocesso inflamatório crônico e persistente na região periapical, quedetermina a presença de lesão com rarefação óssea promovida por algumagente irritante exógeno ou mesmo endógeno como fator predisponente.Nesses casos, a única forma de tentar impedir sua evolução é a remoçãodo agente, por meio do tratamento endodôntico ou da reintervenção. Umpaciente relatava sintomatologia dolorosa à percussão vertical e à palpaçãoapical no dente 11. A imagem radiográfica mostrava reabsorção radicularexterna discreta no terço apical da raiz, provavelmente intensificando asobreobturação pela perda radicular. O plano de tratamento de eleiçãoconstou de desobturação do canal, determinação de novo comprimentode trabalho e instrumentação. Trocas periódicas mensais de pasta de hidróxido de cálcio associada a polietilenoglicol foram realizadas. Apósverificação da estagnação do processo de reabsorção radicular,apresentando radiograficamente uma melhora reparacional significativa,procedeu-se à obturação do canal radicular. As radiografias de controlemostram sucesso após reintervenção com utilização da pasta com atéquatro anos da conclusão do tratamento.
Análise radiográfica do preenchimento de canais laterais por quatro diferentes técnicas de obturação
Authors: Andressa RAYMUNDO  , Cecília Peixoto PORTELA  , Denise Piotto LEONARDI  , Flares BARATTO FILHO
Published: April 2023

Muitas técnicas de obturação têm sido desenvolvidas, especificamentecom o objetivo de aumentar a qualidade do selamento apical com aassociação guta-percha/cimento obturador. O objetivo desta pesquisafoi avaliar, por meio do exame radiográfico, a qualidade dopreenchimento de canais laterais de 60 dentes extraídos, utilizandocimento de Grossman conjuntamente com a aplicação de quatrodiferentes técnicas obturadoras: McSpadden, híbrida de Tagger,Thermafil e condensação lateral. Os resultados foram obtidos com aanálise das radiografias finais, em que se observou a superioridade dosistema Thermafil em relação às demais técnicas testadas para opreenchimento dos canais laterais.
Reparação microcirúrgica de nervo facial de ratos Wistar por meio de sutura – Parte II
Authors: João Armando BRANCHER  , Maria Fernanda TORRES
Published: April 2023

O nervo facial direito de 20 ratos da raça Wistar foi seccionado, e asextremidades foram aproximadas por um ponto simples inicial e envolvidaspor uma bainha de BioFill®. As mudanças histológicas observadas foramproliferação de tecido fibroso, invasão do tecido nervoso por mastócitos efibroblastos e presença de fibrilas de colágeno. O uso da bainha de BioFill®oferece vantagens porque é responsável pelo melhor direcionamento dasfibras nervosas.
Avaliação da infiltração marginal entre uma resina do tipo Flow e um cimento de ionômero de vidro modificado por resina
Authors: Álvaro VOLPATO  , Andressa RAYMUNDO  , Francisco BUJARDAO  , Cleber Machado de SOUZA
Published: April 2023

O objetivo do presente estudo foi avaliar, in vitro, a infiltração marginalentre uma resina do tipo Flow (Fill Magic Flow®) e um cimento de ionômerode vidro modificado por resina (Vitremer®). Selecionaram-se para este estudo40 pré-molares humanos extraídos. Os dentes foram randomizadamenteseparados em dois grupos. Cavidades classe V foram preparadas commargem estendida apicalmente. Todos os dentes foram submetidos àciclagem térmica com 250 ciclos e, em seguida, à fuscina básica 0,5%, paraa análise do grau de infiltração ao longo de todas as paredes do preparo. Apesquisa mostrou que o cimento de ionômero de vidro modificado porresina apresentou os piores resultados (p < 0,05).
Estudo da incidência de fusão dos canais mesiais de molares inferiores por meio da análise em microscópio operatório
Authors: Denise Piotto LEONARDI  , Flares BARATTO FILHO  , Leonardo LASLOWSKI  , Sérgio MONTI JÚNIOR  , Flávia Sens FAGUNDES
Published: April 2023

O conhecimento da anatomia dos canais radiculares é de grandeimportância para que estes sejam adequadamente acessados,instrumentados e obturados e para que aumente a chance de sucessodo tratamento endodôntico. O objetivo do estudo foi avaliar a anatomiade molares inferiores quanto à presença ou não de fusão entre oscanais mesiais por meio do microscópio cirúrgico. No presente estudo,foram utilizados 51 molares inferiores que tiveram seus canaismesiais irrigados com solução de hipoclorito de sódio a 1%. Após alocalização deles efetuaram-se a sua exploração e o seu esvaziamentoutilizando limas manuais de número 10 e 15, até que elasaparecessem no forame apical. A observação da presença de fusãoentre os canais mesiais foi feita com o microscópio cirúrgico, seguindoo método de Stropko [8]. A análise dos dados obtidos mostrou um índice de fusão de 51% (26 amostras com fusão) e um índice de não fusãode 49% (25 amostras com não fusão). Os autores concluíram no presentetrabalho que a fusão e a não fusão dos canais mesiais de molares inferioresaconteceram na mesma proporção, sendo de grande importância oconhecimento desse dado anatômico para a realização de adequado preparobiomecânico, o que possibilita a correta obturação dos canais radiculares.
Estudo da anatomia interna do canal radicular em incisivos inferiores pela técnica de diafanização
Authors: Daniel GALAFASSI  , Dieison Nardi LAZZARETTI  , Aloísio Oro SPAZZIN  , José Roberto VANNI  , Soluete Oliveira da SILVA
Published: April 2023

Para o sucesso da terapia endodôntica, é indispensável o plenoconhecimento da anatomia radicular interna, assim como suasvariações. Os incisivos inferiores são os menores dentes da arcadahumana e apresentam uma raiz fortemente achatada no sentidomesodistal. Esse achatamento é, por vezes, tão grande que determinaa divisão do canal radicular em dois, um vestibular e um lingual. Oobjetivo deste estudo foi analisar por intermédio de diafanização(método que permite observar por transparência a diversificadaanatomia radicular) a incidência do número de canais presentes nosterços cervical, médio e apical da raiz de incisivos inferiores humanos.Para isso foram obtidos 150 dentes no banco de dentes da Faculdadede Odontologia da Universidade de Passo Fundo, nos quais se aplicoua técnica de diafanização e injeção de tinta nanquim no interior dacâmara pulpar, seguida de conservação em salicilato de metila, o quepermitiu observar tridimensionalmente, por transparência, a anatomia interna dos canais radiculares. Os resultados foram submetidos àanálise estatística descritiva, e notou-se que 81,63% dos espécimesanalisados apresentaram um canal no terço cervical, 53,06% tinhamdois canais no terço médio e 71,42% possuíam um canal no terçoapical. Com isso é possível concluir que há maior incidência debifurcação do canal radicular no terço médio da raiz em relação aosterços cervical e apical.
Estudo in vitro da atividade antimicrobiana de soluções irrigadoras na eliminação de Enterococcus faecalis
Authors: Luiz Fernando TOMAZINHO  , Danielli Cristina Cavalcante da SILVA  , Flávia Sens FAGUNDES  , Paulo Henrique TOMAZINHO
Published: April 2023

Bactérias facultativas como Enterococcus faecalis têm sido isoladas depatologias ligadas a canais radiculares, sendo consideradas uma dasespécies mais resistentes da cavidade oral e uma das possíveis causasde falha nos tratamentos endodônticos. O objetivo deste estudo foi avaliar,in vitro, a efetividade de várias soluções irrigadoras na eliminação deEnterococcus faecalis. Foi aplicado o teste de disco-difusão em ágarneste trabalho. A bactéria utilizada foi Enterococcus faecalis (ATCC29212), e as soluções irrigadoras foram NaOCl 0,5%, 1%, 2,5% e 5%;clorexidina 0,12% e 2%; EDTA 17%; e H2O2 10 vol. A clorexidina 2% eNaOCl 5% foram as soluções irrigadoras mais eficientes, e NaOCl 0,5%,EDTA 17% e H2O2 mostraram-se inefetivas na eliminação dessa espécie.Os resultados sugerem que a eliminação de E. faecalis depende daconcentração e do tipo de solução irrigadora utilizada.
Impactação primária de um incisivo decíduo: Relato de caso
Authors: Maria Naira Pereira FRIGGI  , Rosa Maria EID  , Alvaro DUARTE NETO  , Estela Maris LOSSO
Published: April 2023

Retenção primária é a situação na qual um dente fica retido na cavidadebucal e não consegue erupcionar por um período superior a seis mesesem comparação ao dente homólogo. Na dentição decídua é uma condiçãorara, especialmente em dentes decíduos ântero-superiores. O objetivodeste artigo é mostrar o caso de uma criança de 2 anos e 11 meses queapresentou impactação primária de um incisivo central superior. A queixaprincipal era a ausência de dentes anteriores. Na anamnese foi relatadotrauma na região anterior da boca aos 4 meses de idade. Exames clínicoe radiográfico são descritos. O tratamento consistiu em acompanhamentoclínico e radiográfico, extração do dente impactado e acompanhamentoclínico até a erupção do permanente sucessor. Esse caso permite associara retenção primária ao trauma bucal.
A influência de diferentes métodos de ampliação cervical na obtenção do comprimento de trabalho em canais mesiovestibulares de primeiros molares superiores
Authors: Georgia Ribeiro MARTINI  , José Roberto VANNI  , Álvaro DELLA BONA  , Dieison LAZARETTI
Published: April 2023

A ampliação da entrada de canais radiculares com o uso de diferentestipos de métodos e instrumentos é alvo de inúmeras pesquisas naOdontologia. O objetivo deste estudo foi determinar a influência dequatro sistemas distintos de instrumentos rotatórios para alargamentocervical na determinação do comprimento real de trabalho (CRT). Pormeio da comparação entre esses quatro tipos de instrumentosdiferentes que podem ser utilizados pelo profissional, averiguou-se omais efetivo para a ampliação cervical de canais radiculares curvos. Aetapa experimental foi realizada no Laboratório de Endodontia daFaculdade de Odontologia da Universidade de Passo Fundo (FOUPF). O estudo in vitro foi feito com 40 raízes mesiovestibulares de primeirosmolares superiores humanos permanentes, obtidas no banco de dentesda FOUPF. As 40 amostras foram divididas aleatoriamente em 4 gruposde 10 dentes cada, os quais foram submetidos ao acesso endodônticoconvencional. Após a verificação do CRT, aplicaram-se os métodos deampliação cervical em cada grupo, com uso de brocas Gates-Glidden(Dentsply Maillefer, Ballaigues, Suíça) no grupo 1, alargadores rotatóriosde níquel-titânio Orifice Openers (SybronEndo, Glendora, USA) nogrupo 2, instrumentos de níquel-titânio SX e o instrumento S1(ProTaper – Dentsply Maillefer, Ballaigues, Suíça) no grupo 3 e LAAxxess (SybronEndo, Glendora, USA) no grupo 4. Na seqüênciaverificou-se novamente o CRT. A diferença entre a primeira e a segundaodontometria foi calculada (ANOVA), e o teste de comparações múltiplasde Tukey (p ≤ 5%) identificou diferenças significativas entre os gruposavaliados. Os instrumentos rotatórios de níquel-titânio SX e S1 dosistema ProTaper apresentaram os melhores resultados, e osinstrumentos rotatórios de aço inox Gates-Glidden (brocas) tiveramos piores resultados.
Prevalência da xerostomia relacionada à medicação nos pacientes atendidos na Área de Odontologia da UNIVILLE
Authors: Juliano Henrique PEROTTO  , Kesly Mary Ribeiro ANDRADES  , Aleysson Olimpio PAZA  , Lúcia Ferreira de Castro ÁVILA
Published: April 2023

Este trabalho tem por objetivo determinar a prevalência da xerostomianos pacientes que procuraram atendimento na Área de Odontologia daUNIVILLE e sua relação com medicamentos utilizados no tratamentode doenças como hipertensão, convulsão, depressão e outros. Ametodologia consistiu em fornecer aos pacientes um questionário sobreas condições de saúde geral, sintoma de xerostomia e uso demedicamentos. Os pacientes foram separados e analisados de acordocom o medicamento utilizado no tratamento das doenças, bem como osintoma isoladamente. De todos os pacientes atendidos, 24,8%relataram xerostomia. Dos que fazem uso de medicamentos o sintomaesteve associado a 35,9%. Os principais medicamentos relacionadosao sintoma nesse estudo foram anti-hipertensivos, antidepressivos eanticonvulsivantes. A xerostomia tem maior prevalência nos pacientesque fazem uso dos medicamentos mencionados.