bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of regional socioeconomic deprivation on late HIV diagnoses: a cross-sectional study in Germany
Authors: PANTKE Annemarie , KOPPE Uwe , HEIDEN Matthias AN DER , MICHALSKI Niels , HOEBEL Jens , BREMER Viviane , GUNSENHEIMER-BARTMEYER Barbara , BANNERT Norbert , HANKE Kirsten
Published: November 2021

Background: Late HIV diagnoses are associated with significantly poorer health outcomes and facilitate onward transmission. The proportion of HIV infections diagnosed at advanced stages has remained continuously high in Germany. This study examined the effect of regional socioeconomic deprivation on late HIV presentation.Methods: We used data from the national statutory notification of newly diagnosed HIV cases collected between 2011 and 2018 with further information on the timing of diagnosis determined by the BED-Capture-ELISA test (BED-CEIA) and diagnosing physicians. Data on regional socioeconomic deprivation were derived from the German Index of Socioeconomic Deprivation (GISD). Outcome measures were a long-standing infection based on the BED-CEIA result or an infection at the stage of AIDS. The effect of socioeconomic deprivation on the timing of diagnosis was analysed using multivariable Poisson regression models with cluster-robust error variance.Results: Overall, 66.2% (n=6,185) of the patients were diagnosed with a long-standing infection and 13.1% (n=1,536) with AIDS. The proportion of late diagnoses was higher among persons with heterosexual contact compared to men who have sex with men (MSM) (76.5% long-standing and 16.4% AIDS vs. 62.4% long-standing and 11.9% AIDS). MSM living in highly deprived countryside regions were more likely to have a long-standing infection (aPR: 1.16, 95% CI 1.05-1.28) as well as AIDS (aPR: 1.41, 95% CI 1.08-1.85) at the time of diagnosis compared to MSM in less deprived countryside regions. No differences were observed among MSM from urban areas, and no differences overall among persons with heterosexual contact.Conclusions: An effect of socioeconomic deprivation on late HIV presentation was found only in MSM from countryside regions. We suggest that efforts in promoting HIV awareness and regular HIV testing are increased for heterosexual persons irrespective of socioeconomic background, and for MSM with a focus on persons living in deprived regions in the countryside.
Compassionate and Respectful Care From Clients’ Perspectives in Wollega Zones Hospitals, Wollega, West Ethiopia
Authors: Cafo Jote Markos , Bekuma Tariku Tesfaye , Hasen Tahir , Yeyi Worku Dechasa
Published: November 2021

Introduction

: Compassion is a deep awareness of the suffering of another coupled with the wish and action to relieve it. Respecting the patient’s right to self-determination—that is, supporting decisions that reflect the patient’s personal beliefs, values, and interest’s problems. compassionate, respectful and caring (CRC) health workforce initiative in this plan intends to address the concern of Disrespect and Abuse for clients, including laboring mothers.
Objective

Aim of the study is to assess the provision of compassionate, respectful and caring health care services among health care providers based on client’s perspective.
Methods and materials:

Hospital-based cross-sectional study was conducted from December 1-25, 2020. A semi-structured interview administered questionnaire was used to collect data from 351 participants. Epi-Data version and Stata version 14.0 were used for data entry and data analysis, respectively. Bivariable and multivariable logistic regression model was fitted to identify the factors associated with compassionate and respectful care from clinical and non-clinical staff of the selected Hospitals. The Adjusted odds ratio with 95% confidence interval and p-value less than 0.06 were used to declare the strength and association of the factors.
Results

of health care providers were reflected by their being patient while providing care. Clients who were from the poor socio status category were 3.70 times to report getting non compassionate and respectful care from the health care professionals than the clients who are at a better position of wealth status [AOR=3.70(95%CI; 1.27,10.81)]. Similarly, clients with lower grade educational status did not receive compassionate and respectful care when compared to patients with higher educational status [AOR=0.32(95%CI;0.10, 0.99)].
Conclusion

Compassionate and respectful care provided to the patients from health care providers in the selected Hospitals of Western Oromia, Ethiopia was high. However, compassionate and respectful care or services rendered from non-clinician staff was low which suggests that immediate actions are necessary to address compassionate and respectful care at hospitals, and hospital management should adopt mitigation measures and should include non-clinician staff during training on CRC or related topics.
Predicting the growth and feed intake of Bonsmara cattle on forage based rearing systems
Authors: Brand Tertius Swanepoel , Terblanche I. , Merwe Daniel Andre Van der , Jordaan J.W. , Dreyer Olga
Published: November 2021

This study aimed at estimating models to predict the growth and feed intake of Bonsmara bulls and heifers in backgrounding or pasture-based production systems (Ethical clearance number A16-SCI-AGR-001). Growth and intake data were collected from the Kromme Rhee Bonsmara stud in the Stellenbosch region. The growth curves of steers and heifers were modelled using the Gompertz function. Parameter estimates of the function showed that the mature weight (A) parameter was greater (P <0.05) for bulls than heifers (ca. 878.4 vs 562.1 kg, respectively). The maturation rates (parameter B) did not differ between the sexes, while the days at maximum growth (parameter C) was higher for bulls (291.5 days) than for heifers (182.4 days). Linear functions were used to describe the average feed intakes, as well as cumulative intakes, with body weights from growing bulls and heifers from the ages 6-20 months reared on lucerne hay and protein supplement. On average, it was observed that on the lucerne hay-based diet, Bonsmara bulls and heifers consumed about 2.43% of body weight daily throughout the study period. These models can be used in precision beef rearing systems to predict the production and market weights of Bonsmara calves that are either reared on hay or pasture.
H2S Exposure Aggravates Inflammation Induced by LPS in Chicken Liver By microRNA-216a/PKCα Axis Modulating NF-κB/TNFα Pathway
Authors: Guo Jinming , Zhu Wenjing , Yin Yilin , Shi Xu , Xu Shi-wen
Published: November 2021

Background: Hydrogen sulfide (H2S), a common air pollutant and toxic gas, which is harmful to organisms and the environment. Exposure to high concentrations of H2S can lead to necrosis and inflammation. However, the potential mechanism of H2S-induced hepatotoxicity and the role of microRNA (miRNA) in this process are still poorly understood. In this experiment, 80 one-day-old chickens were used as model organisms to evaluate the effects of H2S and Lipopolysaccharide (LPS) on poultry liver. Four groups (Control group, LPS group, H2S group, H2S-LPS group) were established. Liver tissue was collected after 42 days of age. Ultrastructural observation, pathological tissue observation, immunofluorescence analysis, real-time quantitative PCR analysis and Western blot analysis were used to detect.Results: The results showed that obvious pyroptosis was observed in ultrastructure. Histopathological observation showed obvious necrosis and inflammatory injury in broiler liver tissue. By detecting the expression of miR-216a in the four groups, we verified that miR-216a can target chicken PKCα. Molecular level studies showed that H2S exposure could inhibit the expression of miR-216a, promote the up-regulation of PKCα, activate the NF-κB/TNFα signaling pathway, induce cell necrosis (necrosis marker factors RIP1, RIP3, caspase8, MLKL, NLRP3) and pyroptosis-related gene expression (ASC, caspase1, GSDMD), and eventually lead to inflammatory injury of chicken liver (IL-1β, IL-6, IL-18, iNOS).Conclusions: We concluded that H2S induced the imbalance of the NF-κB/TNFα signaling pathway through miR-216a/PKCα axis, leading to chicken liver necrosis and cell pyroptosis, and further causing inflammatory injury. Notably, we also found that H2S aggravated LPS-induced liver inflammation. This study can provide reference to the pathological mechanism of animal damage and poultry poisoning caused by H2S pollution in the atmospheric environment.
Advances In The Modeling And Dynamic Simulation of Reeving Systems Using The Arbitrary Lagrangian-Eulerian Modal Method
Authors: Escalona José L. , Mohammadi Narges
Published: November 2021

This paper presents new advances in the arbitrary Lagrangian-Eulerian modal method (ALEM) recently developed for the systematic simulation of the dynamics of general reeving systems. These advances are related to a more convenient model of the sheaves dynamics and the use of axial deformation modes to account for non-constant axial forces within the finite elements. Regarding the sheaves dynamics, the original formulation uses kinematic constraints to account for the torque transmission at the sheaves by neglecting the rotary inertia. One of the advances described in this paper is the use of the rotation angles of the sheaves as generalized coordinates together with the rope-to-sheave no-slip assumption as linear constraint equations. This modeling option guarantees the exact torque balance the sheave without including any non-linear kinematic constraint. Numerical results show the influence in the system dynamics of the sheave rotary inertia. Regarding the axial forces within the finite elements, the original formulation uses a combination of absolute position coordinates and transverse local modal coordinates to account for the rope absolute position and deformation shape. The axial force, which only depends on the absolute position coordinates, is constant along the element because linear shape functions are assumed to describe the axial displacements. For reeving systems with very long rope spans, as the elevators of high buildings, the constant axial force is inaccurate because the weight of the ropes becomes important and the axial force varies approximately linearly within the rope free span. To account for space-varying axial forces, this paper also introduces modal coordinates in the axial direction. Numerical results show that a set of three modal coordinates in the axial direction is enough to simulate linearly varying axial forces.
Optimierung, Evidenzbasierung, Datafizierung
Authors: Altenrath Maike , Hofhues Sandra , Lange Jennifer
Published: November 2021

Zahlen, Daten und Algorithmen optimieren Lehren und Lernen zunehmend. In der Schule werden sie u. a. genutzt, um Gestaltungs- und Steuerungsanforderungen an Schulentwicklungsprozessen zu unterstützen. Dabei kommt ein kritischer Blick auf das Verhältnis von Optimierung, Evidenzbasierung und Datafizierung vielfach zu kurz. Ziel des Beitrages ist es daher, dieses Verhältnis auf Basis eines systematischen Reviews aus Sicht kritischer Medienpädagogik in den Blick zu nehmen und für den Diskurs aufzuarbeiten. Verfolgt wird die Fragestellung: Wie gestaltet sich das Verhältnis von Daten und Schulentwicklung im internationalen Diskurs? Die Ergebnisse zeigen, dass Schwerpunktsetzungen auf evidenzbasierter Schulentwicklung liegen. Leerstellen werden in Auseinandersetzungen mit technisch erzeugten, unsystematisch erhobenen Daten gesehen. Während meist die ‹bestmögliche› Nutzung digitaler Daten fokussiert wird, werden tiefgreifende Transformationsprozesse von Schule und Schulentwicklung wenig thematisiert.
Ship Maneuvering Prediction based Pivot Point Estimation
Authors: Nedelcu A.
Published: November 2021

In the last years, the size and the number of ships has grown remarkably. At the same time, the size of harbors and ports remain constantly. Asa result, the ship maneuvering in harbors has become more problematic and harder to execute. This is the reason that many sailors affirm that it is an art than a science to execute some maneuverings. Ship maneuvers represented a complex vessel motions influenced most of the time by external environmental conditions in the navigation area (i.e. ocean and tidal current conditions, water depth, wind and waves). Navigator`s knowledge and experiences overcome to control the ship speed, course and heading in some close encounter situations. For example, combinations of different environmental conditions (draft variations in a passage from fresh to sea water with other ships near the same navigation area), create not only additional navigation difficulties, but also could compromise and threatens the navigation.
The happiness gap in the EU strategy: the globalization goals
Authors: G. L. Frecea
Published: November 2021

This paper will outline the EU member states characteristics in the globalization context, following a comparative analysis of the welfare state models from a social perspective. This approach was structured starting from the human resources involvement in all spheres of life, from economic to moral field, requiring an adjusted sense of global citizenship, private and public responsibility. Assuming that the social development is a key issue in the globalization process, the labour force being in the same time both the architects and the passive victims of its composition, the global extension will be considered in accordance with the economic effects of migration, the human development index trend and the demographic considerations. The present paper proposes a complex case study on the European social models in order to provide a link between the social integration and the global benefits, emphasizing in the same time the major losers of the global change. The main results of the analysis strengthen the positive impact of a well-balanced link established between CSR and the state responsibility, identifying also the deficiencies of sharing a common EU agenda that supports the financial returns without a clear focus on the component people in the welfare state dynamism.
Hyperparameters optimisation for time varying signals
Authors: M. Rogobete
Published: November 2021

For the most machine learning methods, for cyclo-stationary or even stochastic signals, the performance depends critically on hyperparameters. Moreover, the tuning of more hyperparameters based on the feedback of the performance model will leak an increasingly significant amount of information about the validation set into the model. Therefore, we propose in this research two classes of hyperparameters, a general class that makes the characterization of general signal curve and the second, a specific class that define special parameters connected to the phenomena type (e.g. sensor type).
Marine industry practical education for engineering
Authors: M. Dumitrescu
Published: November 2021

Practical Education for High level students it is a very important task for every University. Companies have to be involved in the students Practical Engineering Education, considering their know-how and economic support. A very modern and efficient Practical Education has been offered by Alewijnse Holding BV Company, Nijmegen Holland, for Computers, Automation, Electrical and Electronic faculty students in Galati Dunarea de Jos University and is presented in the paper.
DIVERSITE FLORISTIQUE SUR LES PARCOURS DES ENCLAVES PASTORALES DE LA REGION DE NIAMEY (NIGER)
Authors:   Faculte dAgronomie, Universite Abdou Moumouni de Niamey/Niger., Abdoulaye Amadou Hamidou , Barmou Ismael Mahamadou ,   Faculte dAgronomie, Universite Abdou Moumouni de Niamey/Niger., Issa Abdou Kadri Djibrila ,   Faculte dAgronomie, Universite Abdou Moumouni de Niamey/Niger., Zouhoundre Boubacar Adamou ,   Faculte dAgronomie, Universite Abdou Moumouni de Niamey/Niger., Yaye Aissetou Drame ,   Faculte dAgronomie, Universite Abdou Moumouni de Niamey/Niger.
Published: November 2021

Suite a linsecurite grandissante dans la zone de Filingue (a environ 200km au nord-est de Niamey) abritant la station experimentale pastorale de Toukounouss avec ses laboratoires de recherche sur les productions pastorales, des investigations ont ete faites pour trouver au Niger dautres zones plus securisees ou existent des peuplements importants de ligneux fourragers et ou des recherches pourraient Ãªtre entreprises. Cette etude sinscrit dans la perspective devaluer la diversite floristique dans les enclaves pastorales de la region de Niamey. Des recensements floristiques ont ete effectues suivant des transects dans les 9 enclaves pastorales de la region de Niamey pour faire letat des lieux des herbacees et des ligneux sur les parcours. Vingt-cinq (25) especes ligneuses reparties en 12 familles et 19 genres ont ete recensees dont 21,35% de ligneux fourragers. Les Combretaceae (64,10%) sont representees par les especes Guiera senegalensis, Combretum micranthum et Combretum glutinosum, suivis des Capparidaceae (16,72%), puis des Asclepiadaceae (12,72%). Les herbacees sont representes par 17 especes reparties en 9 familles et 15 genres les Gramineae representent 29,41% des genres (Aristida, Brachiaria, Pennisetum et Schoenefeldia). Les Asclepiadaceae, Caesalpiniaceae, Malvaceae et Papilionaceae representent chacune 11,76% de la population et avec chacun 2 genres recenses.La faible presence de diversite floristique au niveau des enclaves pastorales a ete expliquee par le fait que ces zones font lobjet de lotissement urbain, de coupe abusive et selective pour des besoins de service et de fourrage en destination des villages limitrophes et de la ville de Niamey.
ANTIMICROBIAL ACTIVITY OF CHITOSAN, MORINGA OLEIFERA, CROTON ZAMBESICUSAND THEIR SYNERGISTIC ACTIVITY AS AN IMMUNE BOOSTER
Authors:   AdekunleAjasin University, Department of Microbiology. Centre for Infectious Disease Control and Drug Development (CIDCDD), AAU, Akungba-Akoko, Ondo State, Nigeria., A. Ajayi Olajide ,   Centre for Infectious Diseases Control and Drug Development (CIDCDD), AdekunleAjasin University, Akungba-Akoko, Ondo State, Nigeria., D. Miteu Goshen ,   Caleb University, Imota, Lagos, Department of Biochemistry. Centre for Infectious Diseases Control and Drug Development (CIDCDD), AAU, Akungba-Akoko, Ondo State, Nigeria.,   Centre for Infectious Diseases Control and Drug Development (CIDCDD), AdekunleAjasin University, Akungba-Akoko, Ondo State, Nigeria., C. Ezeh Blessing ,   Federal Polytechnic Bauchi, Department of Chemistry/Biochemistry.,   Centre for Infectious Diseases Control and Drug Development (CIDCDD), AdekunleAjasin University, Akungba-Akoko, Ondo State, Nigeria.
Published: November 2021

The plants used for this study were selected from a collection of medicinal herbs collected from traditional healers during a prior ethnobotanical investigation. Chitosan derived from chitin is effective as an antibacterial agent in pharmaceutics. The Mauline, 2017 approach, which incorporates processing/maceration, demineralization, deproteinization, and deacetylation, was used to synthesize chitosan from crayfish and prawns. Moringaoleifera and Croton zambesicuswere chosen for their phytochemical capabilities, including antibacterial, anti-inflammatory, and antioxidant properties. These plants were acquired locally, and combined with the various chitosan extracts in powdered form. They were tested against selected clinically resistant bacterial and fungal isolates. Chitosan extracted from crayfish and the synergized extracts of Chitosan sources with Croton zambesicuswere effective against organisms like Candida albicans, Vibrio cholerae, Enterobacter cloacaeand Salmonella typhiwith 30mm, 13mm and 12mm zones of inhibition respectively. In Table 2, water and diethylether extracts of Croton zambesicus, synergized with one (1%) Chitosan extracted from crayfish were only effective against Bacillus cereus and Eschericha coli. During the experimental stages, both bacteriostatic and bacteriocidal effects were observed in some media cultures however, the overall results from the synergy between Chitosan (crayfish and prawn extracts), Moringa, and Croton zambesicusunderscores the possibilities of exploring these combinations in novel drug designs.
Breeding and genetic peculiarities of spring barley 1000 kernel weight under conditions of the central part of the Ukrainian Forest-Steppe
Authors: Hudzenko V. M. , Polishchuk T. P. , Lysenko A. A. , Khudolii L. V. , Babenko A. I.
Published: November 2021

Purpose. To reveal the breeding and genetic peculiarities for spring barley 1000 kernel weight and to identify genetic sources for breeding under conditions of the central part of the Forest-Steppe of Ukraine.
Methods. Investigations were carried out at the V. M. Remeslo Myronivka Institute of Wheat of the NAAS of Ukraine. Spring barley F1 of two comp­lete (6 ´ 6) diallel crossing schemes was investigated. The first scheme included modern both domestic and foreign spring barley malting varieties (‘MIP Tytul’, ‘Avhur’, ‘Datcha’, ‘Quench’, ‘Gladys’, ‘Beatrix’), the second – classic covered awned (‘MIP Myroslav’, ‘Sebastian’), awnless (‘Kozyr’, ‘Vitrazh’) and naked (‘Condor’, ‘CDC Rattan’) varieties.
Results. Various types of inheritance of 1000 kernel weight were revealed, with the exception of negative dominance. The proportion of combinations with corresponding values ​​of the degree of phenotypic dominance varied depending on the genotypes involved in the crossing and the years of testing. In both crossing schemes, both in 2019 and in 2020, positive overdominance was found in most combinations. The grea­test number of combinations with the manifestation of hete­rosis under different growing conditions was noted when varieties ‘Gladys’ and ‘MIP Myroslav’ were used in crossing. According to the parameters of genetic variation, it was revealed that the trait was determined mainly by the additive-dominant system. The dominance was aimed at increasing the 1000 kernel weight. Only in the second crossing scheme in 2019 the value of the directional dominance indicator was unreliable. In the loci, incomplete dominance in 2019 and over-dominance in 2020 were revealed. Reliably high effects of the general combining ability in both years were noted for varieties ‘Datcha’, ‘Gladys’, ‘MIP Myroslav’, ‘Kozyr’ and ‘Vitrazh’.
Conclusions. The revealed breeding and genetic peculiarities indicate that for the overwhelming majority of created hybrid combinations will be required the final selection in later generations, when the dominant alleles are homozygous. Spring barley awned varieties ‘Gladys’, ‘MIP Myroslav’ and ‘Datcha’, as well as awnless varieties ‘Kozyr’ and ‘Vitrage’ can be used as effective genetic sources for increa­sing the 1000 kernel weight
Activation of peroxymonosulfate by CuCo2O4 nano-particles towards long-lasting removal of atrazine
Authors: Yin Haoxiang , Li Jun , Yan Haoding , Cai Hanying , Wan Yanjian , Yao Gang , Guo Yong , Lai Bo
Published: November 2021

The effect of peroxymonosulfate (PMS) activated by nanocrystalline CuCo2O4 (NPS) on removal of atrazine (ATZ) was studied. First, the main experimental parameters were studied, including CuCo2O4 dose, PMS dose, initial pH value, and co-existing ion. The removal of ATZ (>99%) was attained under the optimal conditions (i.e., 150 mg/L CuCo2O4, 0.2 mM PMS, 5 mg/L ATZ, initial pH value of 6.8, and reaction time of 30 min). However, the removal of ATZ only reached 20.9% in the PMS alone system and there was no significant ATZ removal when adding CuCo2O4 alone into the solution, proving the good performance of the CuCo2O4/PMS system. Furthermore, reusability of CuCo2O4 was tested through five consecutive runs. To confirm which main active radicals were responsible in the system, two radical quenching experiments were carried out and electron paramagnetic resonance (EPR) was tested. In addition, the characterization of fresh and reacted CuCo2O4 NPs was tested by SEM, TEM, EDS, XRD, and XPS. Subsequently, based on the characterization of CuCo2O4 NPs and identification of radicals, ≡Cu2+/ ≡ Cu+ and ≡Co3+/ ≡ Co2+ were considered to be the main catalytic species, while the synergistic effect of Cu and Co played a crucial role. Finally, the degradation pathway of ATZ was proposed.
De los campos del Magdalena a la diplomacia mundial
Authors: Arrieta Lara Pablo Enrique
Published: November 2021

Después de su jubilación del servicio diplomático colombiano, Enrique Arrieta Lara se dedicó a conversar con sus allegados, quienes ven en él a su mejor maestro. Sus constantes charlas con sus estudiantes sobre lo divino y lo humano lo motivaron a escribir algunas de las historias que les contó, y de las cátedras que les dio, para que queden como recuerdo indeleble, sobre todo a las futuras generaciones magdalenenses. Una parte de estos documentos se recopilan aquí. Estos escritos son respuestas que el autor ha dado, en sus didácticas charlas, a preguntas que le han hecho sobre la historia de la diplomacia colombiana, de la que él fue parte. También se incluyen respuestas que el autor ha dado a preguntas sobre su vida personal, la historia colombiana y la internacional y la geopolítica global. El autor nació en los campos del antiguo Magdalena Grande, en el seno de una familia campesina, y él solo se abrió camino en la vida, sin palancas, llegando a ocupar los más altos cargos de la diplomacia de Colombia. Sus relatos cuentan sus interacciones con pontífices, emperadores, reinas, presidentes y otros diplomáticos, siempre dejando en alto el nombre de su amada patria.
ESPAÇO MULTIPICS: A UTILIZAÇÃO DAS PRÁTICAS INTEGRATIVAS E COMPLEMENTARES COMO ESTRATÉGIA DE CUIDADO NA ATENÇÃO À SAÚDE DO TRABALHADOR
Authors: Gondin da Silva Igor , Louise Pereira Estéfany , Fernandes da Silva Claudenir , Marcelino Soares de Brito Kézia
Published: November 2021

Introdução: As Práticas Integrativas e Complementares em Saúde foram regulamentadas no Sistema Único de Saúde, através da portaria nº 971/2006 que aprova a implantação da Política Nacional de Práticas Integrativas e Complementares, com o objetivo de garantir cuidado continuado, humanizado e integral em saúde, com ênfase na atenção primária. Objetivo: Relatar a experiência vivenciada por uma equipe de Residentes Multiprofissionais em Saúde, através do espaço MULTIPICS em uma Unidade Hospitalar na região do Seridó, Rio Grande do Norte/RN. Metodologia: Trata-se de um estudo descritivo com abordagem quantitativa e qualitativa do tipo relato de experiência. Desenvolvido a partir da vivência de uma equipe de Residentes em Atenção Básica da (EMCM/ UFRN), atuantes no município de Caicó-RN em parceria com o Hospital Regional do Seridó (HRS). As ações foram realizadas durante os meses de março e abril de 2021 por meio do espaço MULTIPICS. As práticas desenvolvidas foram ventosaterapia, musicoterapia, arteterapia, meditação guiada e aromaterapia. Após as práticas foi aplicado um questionário semi-estruturado, sobre seu conhecimento sobre as PICS, nível de satisfação e uma descrição subjetiva da experiência e estado atual após a prática. Resultados: Participaram das ações propostas 57 profissionais, dentre eles (84,21%) mulheres e (15,79%) homens, de vários setores da unidade hospitalar. 10,53% relataram desconhecer as práticas de um modo geral e 89,47% relataram não conhecer as práticas que foram ofertadas. De acordo com a pesquisa de satisfação, 98,25% dos profissionais relataram sentir-se "muito satisfeitos" e "satisfeitos", enquanto somente 1,75% consideraram as práticas "neutras".  Os profissionais referiram, também, sensação de harmonia, bem-estar e de paz interior. Conclusões: Por meio da atuação foi possível ofertar um momento de relaxamento no ambiente de trabalho. Obtendo-se após a prática um feedback positivo dos participantes sobre os resultados dessa atuação acerca do seu bem-estar.
QUALIDADE DE VIDA, SINTOMAS DE DEPRESSÃO E ADESÃO AO TRATAMENTO EM PACIENTES COM TRANSTORNO DEPRESSIVO MAIOR
Authors: Felipe Marques Andrade Pedro , Simone da Costa de Souza Karla , Oliveira do Amaral Georgia , Arcoverde Nunes Emerson , Cristiane de Azevedo Ramos Andrea , Queiroz Moura Gabriel , Cristine Rodrigues de Brito Jayane , Dos Santos Rocha Wilton , Diniz de Sousa Lopes Maria Luiza , Antunes de Araujo Aurigena
Published: November 2021

Introdução: Pacientes com depressão maior geralmente respondem ao tratamento com medicamentos antidepressivos, no entanto em 10% a 30% dos casos há apenas uma resposta parcial ou nenhuma resposta, entre os fatores que podem influenciar encontra-se o perfil das enzimas hepáticas metabolizadoras dos antidepressivos, tal como a CYP2C19. Objetivo: Investigar polimorfismos CYP2C19*2 ou CYP2C19*17 em pacientes com transtorno depressivo maior (TDM) tratados com citalopram ou escitalopram e verificar associações com adesão ao tratamento, sintomas de depressão e qualidade de vida. Metodologia: Trata-se de um estudo de série de casos realizado com 29 pacientes com TDM. Amostras de sangue foram coletadas para genotipagem de CYP2C19 por discriminação alélica TaqMan®. Foram coletados dados sobre perfil demográfico e socioeconômico, adesão ao tratamento (escala de Morisky), sintomas de depressão (escala de Hamilton) e qualidade de vida (WHOQoL-BREF). Resultados: Havia quatro pacientes (13.8%) com polimorfismo CYP2C19*2 e 10 (34.4%) com CYP2C19*17. Houve maior prevalência de CYP2C19*17 em comparação com CYP2C19*2 (p>0.05). Em geral, nenhuma associação significativa de características socioeconômicas, demográficas e clínicas com os genótipos CYP2C19. A adesão moderada ao tratamento foi predominante nos pacientes CYP2C19*2 e CYP2C19*17 (p>0.05). Não foi observada associação entre sintomas de depressão e polimorfismos genéticos (p>0.05). Uma associação significativa entre o genótipo polimórfico CC do CYP2C19*17 com a satisfação com a saúde, enquanto o genótipo CT foi associado ao estado “nem satisfeito/nem insatisfeito” (p<0.05). A maioria dos indivíduos CYP2C19*2 e CYP2C19*17 relatou “necessidade de melhorar” em relação aos domínios físico, psicológico, social e ambiental (p>0.05). Conclusões: Os casos estudados apresentaram maior prevalência do polimorfismo CYP2C19*17, com moderada adesão ao tratamento. Muitos pacientes, mesmo sob efeito da medicação, apresentaram sintomas de depressão intensos a moderados, e relataram prejuízo na satisfação com a saúde.
Performance Improvement of Box Girder Construction on Toll Road Projects based on M-PERT and VE
Authors: Husin Albert Eddy , Rahmawati Diah Ika , Meisaroh Myrna , Kussumardianadewi Bernadette Detty
Published: November 2021

Background:

According to the 2019 Global Competitiveness Index (CGI) by the World Economic Forum, the infrastructure growth of Indonesia is placed on number 72 out of 141 countries and ranked 5th in the ASEAN countries. The growth of infrastructure in Indonesia is a result of the imbalance increase of developments of 10-55% annually with only a 1.9% annual increase in road length. There was a delay of 11.95%, with the high investment in the construction of this toll road and the low-interest rate of return of around 7.79%.

Objective:

The expected goal in this research is to have cost and time efficiency in implementing infrastructure on the toll road project.

Materials and Methods:

This research is using a combination of case studies and statistical analysis; the case studies and the implementation of the M-PERT and VE on the object. Statistical analysis using simulation tools Relative Importance Index (RII) analysis based on research instruments to the success of the implementation of Manual Program Evaluation and Review Technique (M-PERT) and Value Engineering (VE) on toll road projects.

Conclusion:

The results of research with the analysis RII reveals that 10 important factors are affecting the performance of a project. The case study using the M-PERT method obtains a value of time accuracy of 98.87% of the real duration needed on site, while the VE method results in a revenue contribution outside of the toll income of 9.38% of the construction cost.
Stereotactic Body Radiation Therapy Boost in Patients With Cervical Cancer Ineligible for Brachytherapy
Authors: FACONDO GIUSEPPE , VULLO GIANLUCA , DE SANCTIS VITALIANA , VALERIANI MAURIZIO , ASCOLESE ANNA MARIA , MASSARO MARIA , ANZELLINI DIMITRI , OSTI MATTIA FALCHETTO
Published: November 2021

Background: Standard treatment for locally advanced cervical cancer is external beam radiotherapy followed by brachytherapy (BT). Stereotactic body radiation therapy (SBRT) is a possible option for treating patients ineligible for BT. Patients and Methods: From October 2012 to July 2020, nine women with cervical cancer received SBRT to high-risk volumes. The Kaplan–Meier method was used to estimate the rates of overall and disease-free survival. Results: The median age was 52 years; 88% of patients had squamous carcinoma. Reasons for forgoing BT were cervical canal stenosis, treatment refusal and hematological disease. The median boost dose was 18 Gy and the median dose per fraction was 6 Gy. Median follow-up was 16 months. The median survival was 24 months, the actuarial 2-year OS rate was 70%, and median disease-free survival was 11 months. One grade 3 late vaginal toxicity was reported. No acute nor late grade 4 toxicities were observed. Conclusion: SBRT boost in patients with cervical cancer ineligible for BT led to acceptable survival outcomes and a safe toxicity profile.
Immune Checkpoint Inhibitor for Non-small Cell Lung Cancer With Negative or Low Tumor PD-L1 Expression
Authors: INOMATA MINEHIKO , TAKATA NAOKI , MIZUSHIMA ISAMI , AZECHI KENJI , HAYASHI KANA , TOKUI KOTARO , TAKA CHIHIRO , OKAZAWA SEISUKE , KAMBARA KENTA , IMANISHI SHINGO , MIWA TOSHIRO , HAYASHI RYUJI , MATSUI SHOKO , TOBE KAZUYUKI
Published: November 2021

Background/Aim: We conducted a retrospective analysis of the survival durations of 25 patients diagnosed as having non-squamous cell non-small cell lung cancer with negative or low tumor programmed death-ligand 1 (PD-L1) expression treated with immune checkpoint inhibitor (ICI) monotherapy. Patients and Methods: The progression-free (PFS) and overall (OS) survival were calculated from the initiation of ICI monotherapy. The association between the patient characteristics and the PFS was analyzed using Cox proportional hazards model. Results: The median PFS was 2.6 months, and the 12-month PFS rate was 9.3%. The median OS was 5.5 months, and the 12-month OS rate was 39.8%. A Cox proportional hazards model identified the neutrophil/lymphocyte ratio and presence of liver metastasis as being significantly associated with PFS. Conclusion: Our findings suggest that a subset of patients with non-squamous cell non-small cell lung cancer who show negative or low tumor PD-L1 expression could benefit from ICI monotherapy.
Benefits, Problems, and Potential Improvements in a Nationwide Patient Portal: Cross-sectional Survey of Pharmacy Customers’ Experiences (Preprint)
Authors: Sääskilahti Maria , Ojanen Anna , Ahonen Riitta , Timonen Johanna
Published: November 2021

BACKGROUND

Patient engagement is a worldwide trend in health care. Patient portals have the potential to increase patients’ knowledge about their health and care and therefore enhance patient engagement. Portal users’ experiences are needed to determine if these portals work appropriately and if there are barriers to achieving the aims that were set before their implementation.

OBJECTIVE

The aim of this study is to analyze pharmacy customers’ experiences of the Finnish nationwide patient portal My Kanta in terms of benefits, problems, and potential improvements.

METHODS

A questionnaire survey was conducted among pharmacy customers in the spring of 2019. The questionnaires (N=2866) were distributed from 18 community pharmacies across mainland Finland to customers aged ≥18 years who were purchasing prescription medicines for themselves or their children aged <18 years. Using open-ended questions, customers were asked about their experiences of the benefits and problems of My Kanta and what improvements could be made. Their responses were encoded and categorized using inductive content analysis, stored in SPSS Statistics for Windows, and analyzed using frequencies.

RESULTS

Of the 2866 questionnaires, a total of 994 (34.68%) questionnaires were included in the analysis. Most respondents were My Kanta users (820/994, 82.5%); of these 820 users, 667 (81.3%) reported at least one benefit, 311 (37.9%) reported at least one problem, and 327 (39.9%) reported at least one potential improvement when using My Kanta. The most commonly mentioned benefits were opportunities to view health data (290/667, 43.5%) and prescriptions (247/667, 37%) and to renew prescriptions (220/667, 33%). The most extensively reported problems with My Kanta were that the portal lacks health data (71/311, 22.8%), navigating the service and searching for information is difficult (68/311, 21.9%), and the delay before health data are incorporated into the service (41/311, 13.2%). The most frequently suggested potential improvements were that My Kanta needs more comprehensive health data (89/327, 27.2%); the service should be easier to navigate and information easier to access (71/327, 21.7%); the service should have more functions (51/327, 15.6%); and health data should be entered into the portal more promptly (47/327, 14.4%).

CONCLUSIONS

Pharmacy customers reported more benefits than problems or potential improvements regarding the use of My Kanta. The service is useful for viewing health data and prescriptions and for renewing prescriptions. However, portal users would like to see more data and functions available in the portal and data searches to be made easier. These improvements could make the data and functions provided by the portal easier to view and use and hence promote patient engagement.
¿Cómo he osado yo hablar en nombre de los muertos? Una reescritura portuguesa de la Comedia
Authors: Gómez-Vázquez José Luis
Published: November 2021

Contemporary Portuguese poetry has also generated dialogue with Dante. In a sharp rewriting, Pedro Eiras transfers the metaphysical worlds from the Italian poet to an XXI century’s reality, in which neither inferno nor purgatorio has lost validity.
Dante y el castigo lenitivo
Authors: González-Torres Armando
Published: November 2021

This text addresses The Divine Comedy from the perspective of its creative origin and focuses on an essential trait of its conception of The Inferno: vengeance. Dante was a public-life protagonist of his times. He bet and made audacious political pacts, which made him suffer a painful exile as a result. In his Hell, Dante does not punish only the universal evil, but he saves his many enemies in a special place and tortures them with the cruelest and inventive punishments. Therefore, it is suggested that in one of the masterpieces of Western literature underlies a feeling of spite that was exalted into the most vigorous and spiritual expression.
Dúvidas de um tradutor
Authors: Eiras Pedro
Published: November 2021

Poem about the doubts of a Dante’s translator
Leisure attitude, stress-related growth, and quality of life during COVID-19-related social distancing
Authors: Han Jee Hoon , Sa Hye Ji
Published: November 2021

The coronavirus disease 2019 (COVID-19) pandemic and related restrictive measures have impacted on leisure activities globally; South Korea is no exception. In this cross-sectional study we identified the need to increase leisure opportunities during social distancing and respond to
changes in leisure activities post-COVID-19. The leisure attitude, stress-related growth, and quality of life of 260 participants were examined via an online survey. Data were analyzed through structural equation modeling. Results show that during social distancing, leisure attitude was positively
associated with stress-related growth, leisure attitude was not significantly associated with quality of life, and stress-related growth was positively associated with quality of life. From a long-term perspective, as leisure activities can improve stress-related growth and quality of life,
education and related discussions must continue to ensure that people hold a positive attitude toward leisure participation.
Non-Cognitive Predictors of Subjective Job Performance in a Sample of Managers, Client Support and Administrative Support Specialists
Authors: Berga Linda , Austers Ivars
Published: November 2021

The present study was designed to distinguish non-cognitive predictors of job performance for various job groups in order to develop a method for identification of the suitability of an employee for positions and career development in organizational settings. This study included personality traits, vocational interests, grit, growth mindset, resistance to change, goal orientation and self-efficacy as potential predictors of job performance from several individual characteristics related to training, learning and job performance found in the literature. The study sample included customer service specialists, support specialists and managers from five different companies in Latvia. The results show that grit, social, conventional, and enterprising interests are significant predictors of subjective job performance. Personality traits, self-efficacy, growth mindset, resistance to change and goal orientation did not predict job performance in this sample. The relationship between subjective job performance and personality traits for conscientiousness and neuroticism is weak. The results are partly in line with other studies. Possible explanations of results and future directions are offered.
Dual Career Support Activities of High-Performance Students-Athletes in the Project “More than Gold”
Authors:   European Athlete as Student Network, Abelkalns Ilvis , Capranica Laura , Doupona Mojca , Paegle Anda , Stonis Janis , Bisenieks Ugis , Sánchez-Pato Antonio , Cánovas-Álvarez Francisco José , García-Roca Juan Alfonso , Leiva-Arcas Alejandro , Meroño Lourdes , Vaquero-Cristóbal Raquel , Figueiredo Pascal , Sarmento António J. , Vaz Hugo , Radu Vasco , Rus Liliana-Elisabeta , Rusu Cristian-Mihail , Ghinassi Oana-Mihaela , Izzicupo Barbara , Di Baldassarre Angela ,   University “Alexandru Ioan Cuza” of Iași,   University of Coimbra,   University “G. D’Annunzio” of Chieti-Pescara,   University of Latvia,   University of Ljubljana,   Catholic University of Murcia – UCAM,   University of Rome Foro Italico
Published: November 2021

One of the European Union’s (EU) priorities in sports is the holistic development of athletes through combining high-performance sports with higher education. Within the ERASMUS+Sport Collaborative Partnership “More than Gold” (MTG, 603346-EPP-1-2018-1-LV-SPO-SCP), the aim of the empirical research was to clarify and analyse the opinions of high-performance athletes of five Member States on the opportunities for Dual Career (DC) implementation as well as support provision for high-performance athletes within their DC implementation. Survey as the research method was chosen applying questionnaire, interview and focus-group discussion as data collection methods. The research sample included in this work comprised 284 athletes. The data obtained revealed the challenges related to overlapping schedules, long distance from the university to the training venue, and the lack of understanding and flexibility from the academic staff, which was especially challenging in the first academic year. The respondents appreciated the support of DC tutors. Finally, the opinion of experts allowed to identify 9 aspects to be implemented within the DC perspective (e. g., access to educational facilities, tutorship, psychological support). Findings urge to implement DC programmes at higher education institutions (HEIs) comprising DC guidance, flexible study and training schedules, customized curricula, distance learning, proximity of training facilities and sports services, psychological and career support services tailored for elite-athletes. Therefore, the More Than Gold Guidelines for HEIs are crucial for the development of the European DC culture.
ENTRE O CULTURAL E O SOCIAL NAS ABORDAGENS GEOGRÁFICAS
Authors: Silva Leonardo Luiz Silveira da
Published: November 2021

Este artigo contempla as grandes divergências que envolvem a abordagem material da cultura e sua desconstrução, por intermédio da avaliação da influência da virada cultural e da Nova Geografia Cultural. Sua relevância reside no fato destas divergências impactarem severamente nas modernas abordagens culturais da Geografia. Conclui-se que, para além da discussão da materialidade da cultura, a apregoada incompatibilidade entre o cultural e o social nas abordagens da Geografia Cultural é falsa, à medida que a reflexão não ontológica pode centrar-se nos efeitos sociais da materialidade mítica.Palavras-Chave: Virada Cultural; Nova Geografia Cultural; Materialidade; Ontologia.
BETWEEN THE CULTURAL AND THE SOCIAL IN GEOGRAPHICAL APPROACHES
Abstract: This article contemplates the great divergences that involve the material approach of culture and its deconstruction, through the evaluation of the influence of the cultural turn and the New Cultural Geography. Its relevance lies in the fact that these divergences have a severe impact on modern cultural approaches to Geography. It is concluded that, in addition to discussing the materiality of culture, the incompatibility between the cultural and the social in the approaches of Cultural Geography is false, as the non-ontological reflection can focus on the social effects of mythic materiality.Keywords: Cultural Turn; New Cultural Geography; Materiality; Ontology.
ENTRE LO CULTURAL Y LO SOCIAL EN ENFOQUES GEOGRÁFICOS
Resumen: Este artículo contempla las grandes divergencias que envuelven el enfoque material de la cultura y su deconstrucción, a través de la evaluación de la influencia del giro cultural y de la Nueva Geografía Cultural. Su relevancia radica en el hecho de que estas divergencias tienen un impacto severo en los enfoques culturales modernos de la Geografía. Se concluye que, además de la discusión sobre la materialidad de la cultura, la pretendida incompatibilidad entre lo cultural y lo social en los enfoques de la Geografía Cultural es falsa, pues la reflexión no ontológica puede enfocarse en los efectos sociales de la materialidad mítica.Palabras clave: Giro Cultural; Nueva Geografía Cultural; Materialidad; Ontología.
A GEOPOLÍTICA DA FRONTEIRA SUL DO MÉXICO
Authors: Monteiro Licio Caetano do Rego
Published: November 2021

O texto é uma resenha crítica do livro “Tiempo de fronteras: una visión geopolítica de la frontera sur de México”, de autoria de Daniel Villafuerte Solís, publicado pela Universidad de Ciencias y Artes de Chiapas. A fronteira sul do México vem sendo objeto de diferentes tipos de estudos por conta do acelerado aumento de fluxos migratórios e de políticas de contenção internalizadas pelo México em relação a seus vizinhos centro-americanos. O livro enfoca essas mudanças a partir de um interessante olhar geopolítico, que passa também pela construção histórica do espaço fronteiriço e suas vias de desenvolvimento.
ASPEK DAN PENILAIAN KESEJAHTERAAN SUBJEKTIF: KEBAHAGIAAN, KEGEMBIRAAN, KEPUASAN DAN KUALITI HIDUP
Authors: Nik Mad Nik Shahrizan , Md Yunus Marzudi , Abdul Azziz Muhammad Shamsinor
Published: November 2021

Subjective well-being is the self-assessment of happiness, pleasure, satisfaction and quality of life, measured specifically and holistically. The assessment of subjective well-being is varied based on the area of focus of the researcher. Events that occur over some time also could affect an individual’s evaluation. Various factors assess well-being, such as character, love, wisdom, excitement and experiences leading to a good life. The evaluation of the positive and negative effects also affects the subjects’ emotions and mood during a study. Earlier studies showed that well-being is not merely related to income and ownership, but issues on health, activities, personality, emotions, mood, family, environment and various other factors. Therefore, this article aims to discuss aspects, assessment methods, theories and progress based on articles, books and research related to subjective well-being. This study utilises the literature review approach to collect data on subjective well-being. The finding shows that the level of subjective well-being is diverse and dynamic, and not limited to certain aspects and factors that could affect humans. Keywords: subjective well-being; self-assessment; happiness; life satisfaction; quality of life.