bluuebunny/crossref_metadata_2025 huggingface dataset:
Center for Intensive Language Education at Algiers 2 University: difficulties, obstacles and prospects
Authors: Бен Отман.З.М.
Published: September 2023

В статье мы пытаемся обозначить видения, мнения, высказывания и теории некоторых российских выдающихся ученых и дидактиков в области образования и преподавания РКИ о Центре интенсивного языкового образования при Университете «Алжир-2», в котором мы работали. Кроме этого, мы расскажем о своем опыте в Центре, попытаемся подробно сказать о проблемах и трудностях, с которыми как преподаватели, так и учащиеся сталкиваются при приобретении навыков, знаний и опыта в сфере РКИ. Следует отметить, что эта работа является одной из серии статей, которые мы пишем о преподавании и обучении РКИ в Алжире.

In this article, we are trying to project the visions, opinions, statements and theories of some Russian eminent scientists and dedacticians in the field of education and teaching of Russian as a foreign language, directly or indirectly, onto the Center for Intensive Language Education at the Algiers-2 University, where we worked. In addition, we talk about our experience at the Center, describing it and trying to talk in detail about the problems and difficulties that both teachers and students face in their work in acquiring skills, knowledge and experience in the field of Russian as a foreign language. It should be noted that this article is one of many articles that we have written, are writing and will continue to write about teaching and learning Russian as a foreign language in Algeria, hoping that these articles will result in a book in the near future.
Impacto Económico y Administrativo de la Reforma Laboral en Materia de Vacaciones Dignas en México
Authors: Lagunas Sosa Ma de Lourdes , Rivera Corona José Guadalupe , Gámez Almaraz Delfina , Pineda Ullua José Luis , Merino González Emma Liliana
Published: September 2023

El presente trabajo tiene como objetivo analizar la reforma en materia de vacaciones, la cual entro en vigor a partir del 1° de enero de 2023. Se realiza un estudio cualitativo que consiste en la revisión de la literatura y la opinión de los expertos. De ello se desprenden algunos factores económicos y administrativos que los empresarios y trabajadores deben de tomar en cuenta ante este cambio en el contexto laboral. Se concluye en el estudio que los cambios efectuados en la Ley Federal del Trabajo traerán consigo beneficios para los trabajadores, debido al gozo de más días de descanso, mayores momentos de esparcimiento con la familia y mejoramiento de su salud mental, aunque las empresas deben estar preparadas por el aumento de cargas económicas en el aspecto de seguridad social y trabajo administrativo en el área de recursos humanos.
Burnout en Trabajadores de la Salud en un Módulo de Atención Respiratoria Durante la Pandemia por SARS COV2.
Authors: Martinez Macedo. Zyanya Guadalupe , Corona Lara Judith Magdalena , Escobar Lazcano. Mayra Estefanía , Jiménez Rancaño. Alma Osiris , Lerma Narváez. Kattia Shantal
Published: September 2023

Durante la pandemia por COVID 19, los trabajadores de la salud enfrentaron mayor estrés laboral. La presente investigación tuvo como objetivo explorar las dimensiones del síndrome de burnout (desgaste emocional, despersonalización y baja realización personal) en trabajadores de la salud de un módulo de atención respiratoria de la Ciudad de México durante la pandemia por SARS- COV-2.  Se realizó una encuesta transversal en 70 participantes: 2 asistentes médicas, 9 auxiliares de limpieza e higiene, 15 enfermeras, 4 médicos no familiares, 10 médicos familiares, 11 médicos residentes, 13 laboratoristas y 6 químicos. Se encontró que 34 trabajadores (48.6%) tenía afectación en al menos una dimensión y 5 trabajadores (7.14%) cumplían con la definición de burnout establecido al presentar afectación en las 3 dimensiones evaluadas por el Inventario de Burnout de Maslach. Respecto a la categoría laboral, se encontraron diferencias estadísticamente significativas entre los grupos (p<0.05) al aplicar test de Fisher, ya que los médicos residentes y los médicos familiares presentaron mayor agotamiento emocional mientras que los auxiliares de limpieza e higiene la más baja realización personal. Sugerimos que las estrategias dirigidas a la prevención de esta entidad consideren cuáles son las áreas más afectadas según el puesto específico de trabajo.
NANOEMULSION-BASED MOUTHWASH OF ETHYL ACETATE FRACTION OF SERAI WANGI STALK: FORMULATION, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY TEST
Authors: Permatasari Desy Ayu Irma , Veranita Weri , Soraya Novalisa Nindhi , Kholifah Eva
Published: September 2023

Serai wangi or citronella (Cymbopogon nardus L.) has long been used in Indonesia as a component of traditional medicine. A recent study aimed to determine the antibacterial activity of the most active fraction of Citronella stalk extract and to formulate it  into a nanoemulsion mouthwash. Fractionation of the ethanolic extract was carried out using liquid-liquid extraction, and it was found that the ethyl acetate fraction (EAF) was the most active. This fraction was then varied at concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.5625%, and 0.78125% for the antibacterial activity test using the disc diffusion test method. To determine the potency of microbial activity, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated. Subsequently, the ethyl acetate fraction was formulated into a nanoemulsion and characterized by measuring the transmittance percentage, droplet size, and polydispersity index (pdI) using a particle size analyzer. The results showed that the ethyl acetate fraction at a concentration of 25% obtained an inhibition zone diameter of 10.67 mm. MIC and MBC values ??were obtained at a fraction concentration of 6.25%. In addition, characterization of formulae exhibited particle size and pdI as follow 101.6 nm and 0.681 (Formula I); 84.1 nm and 0.609 (Formula II); 108.3 nm and 0.527 (Formula III).
 Keywords:  Citronella stalk; fractionation; Streptococcus mutans; nano-emulsion; mouth wash
SEMANTIC FIELD: VARIANITY, FUNCTIONALITY, PROJECTION
Authors: Marchuk Liudmyla
Published: September 2023

Using the term semantic field in the work, we consider it as a symbolic model of the organization of the sector of extralinguistic  reality, which has a complex structure, the core of which is a concept, around the nuclear sphere – a set of concepts similar to the  synonymous core and actualized in micro- and macro-contexts, and the periphery - interpretations of these texts and concepts.
In a broad  sense, semantic fields make up a picture of the world, but have blurred boundaries. This means that in the process of the development of  linguistic culture, there is a continuous interpenetration and mutual influence of conceptual fields opposed in meaning.
We introduce the  lexeme suit into the semantic field “suit”, which has a multidimensional structure, since its elements illustrate not only linguistic means, but  also cultural extralinguistic choices. Therefore, we insist on linguistic and extralinguistic factors that create the filling of the named field.
We consider the linguistic parameters that regulate the allocation and description of a specific semantic field and declare it as follows: the  formation of SP takes place around a defined integral meaning, taking into account objective external factors and the real capabilities of the  researcher; the composition of SP includes those lexemes in the semantic structure of which there is a sema, which received the status of  integral for the studied verbal group; the semantic structure of the constituents of the field is qualified based on the dictionary definition;  according to the position of the integral semantic component in the content of the lexical unit, its place in the SP structure is determined - in  the nuclear, central or peripheral part.
Extralinguistic factors include: 1) social roles that determine the specificity of the semantic field of costume; 2) human habits; 3) wealth / poverty; 4) the person’s age; 5) the cultural stratum to which a person belongs, perhaps some fashion trend; 6) season, time of day, area, place of event; 7) author’s speech: the filling of the semantic field “costume” depends on linguistic and extra-linguistic factors, among which  is the image of the author, because it is through him, through the choice of language means, that we have different semantic fields in artistic texts; 8) fashion.
DISPLAY OF CHANGES IN THE FUNCTIONING AND SEMANTICS OF THE TERMS IN THE INTERPRETATIVE DICTIONARY OF THE ACTIVE TYPE
Authors: Kysliuk Larysa
Published: September 2023

The article analyzes the processes of terminating, determinating, transterminating and reterminating vocabulary. These processes are actively manifested in modern socio-political and military vocabulary and terminology in the war period of 2022–2023 based on the material of modern texts of various styles.
Terminating of commonly used vocabulary means the development of the semantic potential of the word, which expands the functioning of the word in compounds, which further aspectualize the original concept in specialized texts (corridor, cauldron, arrival). Special
vocabulary is determined as a result of its metaphorization and subsequent functioning in non-special texts (base, zero). As a result, new meanings develop in the semantic structure of a multi-meaning word. Transterminating is called “migration” of a term from one special
field to another (package, plate). Reterminating is the growth of special values in the term (blackout).
The possibilities of displaying these processes in the explanatory dictionary of the active type are shown. If we are talking about the terminating of a commonly used lexeme, then a new meaning may appear in the dictionary article with a note that indicates the scope of the term. If determinating occurs, a new non-special meaning of the register unit with corresponding illustrations from journalistic and artistic texts can be added to the structure of the dictionary article; and it is possible to reflect transterminating or reterminating in a dictionary article by submitting a new terminological meaning of the register unit with a note indicating the scope of its functioning and with appropriate illustrations.
It has been found that the considered processes become the cause of further specialization of terms in various industry terminology systems and their migration from one industry to another. As a result, it is possible to increase the ambiguity of terms and the emergence of homonymous terms.
Tolmo de Minateda: Cuando Hellín aún no lo era, Historia y relatos
Authors: Abad Casal Lorenzo
Published: September 2023

Este libro tiene su base en los trabajos de investigación desarrollados desde hace más de tres décadas. En el Tolmo de Minateda, la arqueología ha permitido sacar a la luz un importante complejo histórico y cultural de muchos siglos de duración, reflejado en este libro a través de historia lineal, reflexiones de los autores y relatos que permiten revivir momentos importantes en la vida de la ciudad y de sus pobladores.
Veröffentlichungspflichten
Authors: Dörenbach Stella
Published: September 2023

Der Beitrag widmet sich den Veröffentlichungspflichten aus einfachgesetzlicher Sicht. Es wird ein systematischer Überblick über die bestehenden rechtlichen Regelungen sowohl auf Bundes- als auch auf Landesebene gegeben. Zudem folgt eine kritische Auseinandersetzung mit den bestehenden Veröffentlichungspflichten.
INFLUÊNCIA DA AUTOESTIMA NA MANUTENÇÃO DA MOTIVAÇÃO NO PROCESSO DE APRENDIZAGEM
Authors: Rêgo Liliana Corrêa , Santiago Antônio do Nascimento , Campos Tiago Aparecido de Melo , Rodrigues Michele Aparecida Cerqueira
Published: September 2023

Relações entre autoestima, aprendizagem e motivação são discutidas em diversas pesquisas com temas educacionais. Teóricos como Vygotsky e Piaget, já sinalizam o quão importantes são esses contextos. Nesta perspectiva, este estudo teve como objetivo investigar a relação entre autoestima, aprendizagem e motivação. Por meio de pesquisa bibliográfica qualitativa, foram selecionados sete artigos relevantes, abordando esse tópico em bases de dados nacionais e internacionais. Descobriu que atitudes e comportamentos positivos podem impactar significativamente o desenvolvimento cognitivo, enquanto o bullying impacta negativamente a autoestima e a motivação. O estudo sugere que a educação contextualizada, o construtivismo, a pedagogia relacional e a gamificação podem melhorar os ambientes educacionais. Por fim, enfatiza a importância de os professores compreenderem e promoverem a motivação dos alunos.
The Closest View of a Fast Coronal Mass Ejection: How Faulty Assumptions Near Perihelion Lead to Unrealistic Interpretations of PSP/WISPR Observations
Authors: Patel Ritesh , West Matthew J. , Seaton Daniel B. , Hess Phillip , Niembro Tatiana , Reeves Katharine K.
Published: September 2023

We report on the closest view of a coronal mass ejection (CME) observed by the Parker Solar Probe (PSP)/ Wide-field Imager for Parker Solar PRobe (WISPR) instrument on 2022 September 5, when PSP was traversing from a distance of 15.3 to 13.5 R
⊙ from the Sun. The CME leading edge and an arc-shaped concave-up structure near the core were tracked in the WISPR field of view using the polar coordinate system for the first time. Using the impact distance on the Thomson surface, we measured the average speeds of the CME leading edge and concave-up structure as ≈2500 ± 270 km s−1 and ≈400 ± 70 km s−1 with a deceleration of ≈20 m s−2 for the latter. The use of the plane-of-sky approach yielded an unrealistic speed of more than 3 times this estimate. We also used single viewpoint STEREO/COR-2A images to fit the Graduated Cylindrical Shell (GCS) model to the CME while incorporating the source region location from Extreme-Ultraviolet Imager of Solar Orbiter and estimated a 3D speed of ≈2700 km s−1. We conclude that this CME exhibits the highest speed during the ascending phase of solar cycle 25. This places it in the category of extreme-speed CMEs, which account for only 0.15% of all CMEs listed in the CDAW CME catalog.
Galactic ChitChat: Using Large Language Models to Converse with Astronomy Literature
Authors: Ciucă Ioana , Ting Yuan-Sen
Published: September 2023

We demonstrate the potential of the state-of-the-art OpenAI GPT-4 large language model to engage in meaningful interactions with Astronomy papers using in-context prompting. To optimize for efficiency, we employ a distillation technique that effectively reduces the size of the original input paper by 50%, while maintaining the paragraph structure and overall semantic integrity. We then explore the model’s responses using a multi-document context (ten distilled documents). Our findings indicate that GPT-4 excels in the multi-document domain, providing detailed answers contextualized within the framework of related research findings. Our results showcase the potential of large language models for the astronomical community, offering a promising avenue for further exploration, particularly the possibility of utilizing the models for hypothesis generation.
Ardisia recurvipetala (Primulaceae-Myrsinoideae), a new species from northern Peninsular Malaysia
Authors: Julius Avelinah , Siti-Munirah Mat Yunoh , Utteridge Timothy M. A.
Published: September 2023

Recent fieldwork in Terengganu, Peninsular Malaysia, resulted in the collection of an endemic new species of Ardisia, described here as Ardisia recurvipetala Julius, Siti-Munirah & Utteridge. The species is a member of subgenus (§) Crispardisia on account of its vascularised glands (bacterial nodules) on the leaf margin and the terminal inflorescence on a specialised lateral branch subtended by a normal leaf (rather than a reduced bract-like leaf). Ardisia recurvipetala is unique amongst all members of §Crispardisia by having leaf margins with both vascularised glands and pustule-like structures and can be further distinguished from other Peninsular Malaysian members of this subgenus by the lamina raised between the leaf venation giving a somewhat bullate appearance, unbranched inflorescences, brownish-red pedicels and recurved corolla lobes, each with a creamy-white apex and a small pink patch at the base. Ardisia recurvipetala is known only from a single location in Terengganu and its conservation status is assessed as Data Deficient (DD).
Measurement-Based Care Implementation Challenges and Opportunities in Real-World Practice
Authors: Ridout Kathryn K. , Vanderlip Erik R. , Ridout Samuel J. , Alter Carol L.
Published: September 2023

Measurement-based care is an evidence-based practice shown to improve patient outcomes in a variety of psychiatric disorders compared to usual care. Despite the evidence, measurement-based care is not routinely implemented in real-world clinical practice. This report uses an implementation science framework to review the literature regarding perceived barriers and facilitators to real-world measurement-based care implementation at the patient, clinician, organizational, and systems level. Further, we highlight the importance of treatment guideline implementation in parallel with measurement-based care, which helps ensure clinician action responsive to symptom measurement.

[
Psychiatr Ann
. 2023;53(9):405–409.]
DiGeorge Syndrome With Atypical Psychotic Symptoms: The Need for a Multidisciplinary Methodology
Authors: Okutucu Fatma Tuygar
Published: September 2023

DiGeorge syndrome (DGS), known as 22q11.2 deletion syndrome or velocardiofacial syndrome, is one of the most common microdeletion syndromes in humans. Developmental delay, intellectual disability, congenital cardiac and gross vessel anomalies, hypocalcemia, and hearing loss may be seen and characterized by dysmorphic facial features. The syndrome has high risk for psychiatric disorders, specifically intellectual disability and psychotic disorders. Dysmorphic features may be overlooked and the diagnosis may be delayed for years. We explore a case of DGS with intellectual disability and atypical psychotic symptoms. A 19-year-old female patient had atypical psychotic symptoms, dysmorphic facial features, and unilateral hearing loss. Intellectual disability was detected in the IQ test evaluation. A detailed investigation and genetic evaluation resulted in a diagnosis of DGS. This case report highlights the variable clinical presentation of DGS in each patient and the need for a multidisciplinary methodology to diagnose and treat it.

[
Psychiatr Ann
. 2023;53(9):432–435.]
Characteristic period analysis of the Chinese stock market using successive one-sided HP filter
Authors: Liu Yuxia , Zhang Qi , Xiao Wei , Chu Tianguang
Published: September 2023

Time series of stock indices usually exhibit nonstationary and chaotic behavior. Analysis of the characteristics of the business cycle can reveal pertinent insights into the evolution of the stock volatility. This paper studies the characteristic periods of three main Chinese stock indices, i.e., the Shanghai composite index (SHCI), the Shenzhen component index (SZCI), and the Hang Seng index (HSI). We propose an approach based on the successive one-sided Hodrick-Prescott (SOHP) filtering and wavelet analysis of the empirical data from the stock markets, to detect their characteristic periods. In particular, the SOHP filter, which preprocesses the time series with a moving-horizon optimization procedure, enables us to extract the volatility cycles in different time scales from a stock time series and reduce noise distortion. The characteristic period of the stock index is then determined by the maxima of the wavelet power spectrum of the filtered data. The evolution of the characteristic period in time demonstrates rich information concerning the period stability of the stock market, as well as the cause and effect of the stock crash. To facilitate solving the moving-horizon optimization issue of the SOHP filter, we also present an incremental HP filtering algorithm, which greatly simplifies the involved inverse matrix operation in the HP-type filters.
Possible magnetic performances of graphene-oxide and it's composites: A brief review
Authors: Chandra Ray Sekhar
Published: September 2023

Carbon-based nanostructured materials are very promising for spintronic applications due to their weak spin-orbit coupling and potentially providing a long spin lifetime. Nanostructured carbons are not magnetic materials, but intrinsic magnetic behavioral nanostructure carbon materials could be fabricated through qualitative alterations. On alterations of carbon nanostructured materials, it changes their critical temperature and magneto-crystalline anisotropy energy that could be useful as favorable magnetic materials for different magnetic/electromagnetic device-based applications. Different processes are used for the alteration of nanostructure carbon materials like chemical doping, introducing defects, changing the density of states, functionalization, intercalation, forming heterostructure and fabricating nanocomposites layered semiconductor materials. Among the carbon-based derived nanostructured materials, the graphene oxide (GO) gets attracted towards the magnet forming in the spin-like structure across the area of the magnet. Due to its magnetic behaviour, it is used for the adsorption of metals and radionuclides and to make nonconductive oxide-metal. In this review article, the basics of magnetic behavioral change of the carbon-based GO/GO-nanocomposites nanostructured materials are described by gathering information from the literature that were/are reported by different researchers/research groups worldwide.
Adaptive rotation attention network for accurate defect detection on magnetic tile surface
Authors: Luo Fang , Cui Yuan , Wang Xu , Zhang Zhiliang , Liao Yong
Published: September 2023

Defect detection on magnetic tile surfaces is of great significance for the production monitoring of permanent magnet motors. However, it is challenging to detect the surface defects from the magnetic tile due to these issues: 1) Defects appear randomly on the surface of the magnetic tile; 2) the defects are tiny and often overwhelmed by the background. To address such problems, an Adaptive Rotation Attention Network (ARA-Net) is proposed for defect detection on the magnetic tile surface, where the Adaptive Rotation Convolution (ARC) module is devised to capture the random defects on the magnetic tile surface by learning multi-view feature maps, and then the Rotation Region Attention (RAA) module is designed to locate the small defects from the complicated background by focusing more attention on the defect features. Experiments conducted on the MTSD3C6K dataset demonstrate the proposed ARA-Net outperforms the state-of-the-art methods, further providing assistance for permanent magnet motor monitoring.
Análisis estratégico de la producción científica española por campos: Ciencias Naturales, Médicas y de la Vida
Authors: Luque-Martínez Teodoro , Luque-Raya Ignacio M.
Published: September 2023

La investigación es una misión fundamental de la universidad que determina la producción científica, que, a su vez, está asociada al desarrollo social y económico. Los indicadores bibliométricos proporcionan una medida de la producción científica. Por otro lado, la medida de dicha producción distinguiendo por campos y especialidades es mucho más útil y permite conocer interesantes detalles para la gestión, tanto de una universidad como de un sistema universitario. Utilizando los indicadores bibliométricos del ranking ARWU, se analiza por campos y especialidades con especial énfasis en las universidades españolas. Se identifican los puntos fuertes y débiles por especialidad en cuanto a volumen y calidad de la producción, impacto, reconocimiento y colaboración internacional, así como el posicionamiento internacional de las universidades españolas. De todo ello se derivan recomendaciones para la gestión.
Performing Facial Recognition Using Ensemble Learning
Authors: Chetty Layton , Odowa Abshir , Avenido Aeron Christler , Hussein Ismail , Elakkad Yassin
Published: September 2023

Investment in facial recognition technologies has increased recently with the amount of venture capital invested in facial recognition startups dramatically increasing in 2021. Facial recognition uses AI and ML techniques to find human faces in the surrounding area. Facial recognition technology is used by the web application Automated Attendance System (AAS) which was developed by a group of students from the University of Wollongong in Dubai to automate attendance management in educational institutions. AAS is simple to use, quick to implement, and can be incorporated into current educational institutions. Deep convolutional neural networks, notably the VGG19 and EfficientNetB0 models, are the foundation of the system. These models were trained for high accuracy utilizing transfer learning and ensemble learning. The automation of attendance tracking reduces human error; increases efficiency, accuracy, and integrity; and does away with the need for manual methods of collecting attendance.
Tracking Public Financing of Adaptation Projects for Developing Economies Using a Climate Budget Tagging Framework for Nigeria
Authors: Onyimadu Chukwuemeka Onyebuchi , Uche Sunday Daniel
Published: September 2023

There is ample evidence in the literature that developing countries would suffer the most from the adverse effects of climate change. Although, respective developing economies have dedicated action plans to mitigate or adapt to these adverse effects, financing for these strategies may be lacking or national governments may not commit financial resources to actualizing these strategies. Using a budget analysis and climate budget tagging framework, the chapter evaluates the financial resources the Nigerian government has committed to its adaptation strategies as stipulated in the 2011 National Adaptation Strategy and Plan of Action on Climate Change (NASPA – CCN). The study found out amongst others that government expenditure on climate change tends to be more of mitigation than adaptation. In addition, adaptation programs targeted at the industry, commerce, telecommunications, and transport sector are most neglected among other sectors highlighted as priority sectors in the NASPA – CCN policy.
Community awareness and perceptions on microplastics: a case study from Sri Lanka
Authors: Premarathna K. , Abeysundara S. P. , Gunaratne A. M. T. A. , Madawala H. M. S. P.
Published: September 2023

Microplastic (MP) pollution is a global issue due to its unprecedented impacts on the environment and human health. However, its place as a potential pollutant and possible impacts on plant and human health are less understood among the general public. The study was conducted to investigate the level of awareness of MP pollution and its impacts and to evaluate their practices and perceptions of plastic usage, and their awareness on regulatory measures in Sri Lanka. The convenience sampling method was employed to select the study population representative of both rural and urban areas. A questionnaire was distributed among 166 respondents belonging to the age group of 20 - 40 years. Nearly 67% and 68% of respondents were aware of MPs and their harmful impacts, respectively. Nevertheless, most respondents (66 %) were not aware of the regulatory measures introduced by the authorities to control the usage of plastic products. About 66% of respondents discarded plastic items on a daily or weekly basis indicating their widespread usage among the general public in Sri Lanka. However, a majority (85%) were unaware that burning of plastics is a prohibited action in the country. The results revealed that the awareness of MPs and their impacts were significantly linked to the gender, level of education, and occupation of respondents, though their awareness on regulatory measures did not show any relationship with the tested demographic characteristics. Unemployed respondents (98.4%) were more mindful of the non-biodegradable nature of plastics than that of students and employed respondents, indicating that the level of education has no link with their awareness of plastics and their characteristics. Despite reasonably high awareness on MPs, the study highlights the necessity of introducing effective strategies to enhance the awareness of regulatory measures to control plastic usage and safe disposal mechanisms among the general public to manage MP pollution in Sri Lanka.
TGF-β Promotes the Postselection Thymic Development and Peripheral Function of IFN-γ–Producing Invariant NKT cells
Authors: Morgan Roxroy C , Frank Cameron , Greger Munmun , Attaway Mary , Sigvardsson Mikael , Bartom Elizabeth T , Kee Barbara L
Published: September 2023

IFN-γ–producing invariant NKT (iNKT)1 cells are lipid-reactive innate-like lymphocytes that are resident in the thymus and peripheral tissues where they protect against pathogenic infection. The thymic functions of iNKT1 cells are not fully elucidated, but subsets of thymic iNKT cells modulate CD8 T cell, dendritic cell, B cell, and thymic epithelial cell numbers or function. In this study, we show that a subset of murine thymic iNKT1 cells required TGF-β–induced signals for their postselection development, to maintain hallmark TGF-β–induced genes, and for expression of the adhesion receptors CD49a and CD103. However, the residency-associated receptor CD69 was not TGF-β signaling–dependent. Recently described CD244+ c2 thymic iNKT1 cells, which produce IFN-γ without exogenous stimulation and have NK-like characteristics, reside in this TGF-β–responsive population. Liver and spleen iNKT1 cells do not share this TGF-β gene signature, but nonetheless TGF-β impacts liver iNKT1 cell phenotype and function. Our findings provide insight into the heterogeneity of mechanisms guiding iNKT1 cell development in different tissues and suggest a close association between a subset of iNKT1 cells and TGF-β–producing cells in the thymus that support their development.
Extraocular cutaneous sebaceous carcinoma in a patient with Muir-Torre syndrome: special emphasis on histologic and dermoscopic features
Authors: Savoia Francesco , Medri Matelda , Melandri Davide , Domeniconi Lucia , Crisanti Emilia , Sechi Andrea , Stanganelli Ignazio
Published: September 2023

Cutaneous sebaceous carcinoma can be classified into periocular and extraocular and can occur as part of Muir Torre syndrome. It is usually a pink-red or yellow solitary nodule, mainly located in the head and neck region. According to the Literature, dermoscopy is characterized in most cases by yellow color, polymorphic vessels and ulceration. We performed a review of the Literature and we found 14 papers describing the dermoscopic features of 33 sebaceous carcinomas, to which we added a case that we have recently observed. Compared to the data of the Literature and in particular to the latest published reviews, we found that milky-red areas are frequently observed in CSC (47% of the cases) and can be added to the main dermoscopic features for the diagnosis. Histology showed, in our case, some features that were consistent with a cutaneous sebaceous carcinoma with a secretory pattern, and other features that were instead consistent with a non-secretory pattern. This was probably due to the fact that the lesion we observed was a moderately differentiated and not well-differentiated cutaneous sebaceous carcinoma. The presence of a cutaneous sebaceous carcinoma should always alert the clinician on the possible association with Muir-Torre syndrome and immunohistochemistry for mismatch repair genes defects can help in the diagnostic pathway.
XXXII Convegno Nazionale dell’Associazione Italiana Veterinari Igienisti (AIVI) | Maierato-Vibo Valentia, 13-14-15 Settembre 2023
Authors: Editors The
Published: September 2023

This abstract book contains the abstracts presented at the 32nd AIVI National Congress, Maierato-Vibo Valentia, 13-14-15 September 2023. [Abstract book in Italian].
Aortic root diameter, main pulmonary artery diameter/aortic root diameter and pericardial fat volume as predictors of occlusive coronary artery disease
Authors: Al-Mosawi Abdulameer A. , Nafakhi Hussein , Hameed Hadeel K.
Published: September 2023

The clinical relevance of aortic root diameter (ARD) and main pulmonary artery diameter (MPAd) or pericardial fat volume (PFV) in the assessment of coronary artery disease (CAD) is largely unknown. We aimed to assess the relationship of pericardial fat volume (PFV), ARD, MPAd, and MPAd/ARD ratio with occlusive CAD (stenosis>50%).This cross-sectional study included patients who had chest pain suggestive of CAD and underwent a 64-multislice multi-detector CT angiography exam to exclude occlusive CAD presence. A total of 145 patients were enrolled in this study. The mean age was 54±10 years, 51% were males. The mean PFV, ARD, MPAd, and MPAd/ARD ratio in all patients were 155 cm3, 29.9 mm, 23.4 mm and 0.8, respectively. On univariate analysis, PFV (OR (CI)=1.1 (1.01-1.3), P<0.01), ARD (OR (CI)=1.2 (1.1-1.4), P<0.01), and MPAd/ARD ratio (OR (CI)= 0.2 (0.1-0.5), p=0.02) showed significant association with occlusive CAD presence. After adjusting for cardiac risk factors, only PFV (OR (CI)=1.1 (1.02-1.3), p<0.01), but not ARD (OR (CI)=0.9(0.3-2), p=0.85) or MPAd/ARD ratio (OR (CI)=0.1(0.1-2), p=0.69), was independently associated with occlusive CAD. In conclusion, increased PFV, but not ARD or MPAd/ARD ratio, showed a significant and independent association with occlusive CAD presence in patients with chest pain suggestive of CAD.
Diversity and species composition of microbiota associated with dengue mosquito breeding habitats: A cross-sectional study from selected areas in Udapalatha MOH division, Sri Lanka
Authors: Kumari Yashoda , Amarasinghe Deepika , Ranasinghe Koshila
Published: September 2023

Objective:

To determine the diversity of microbiota associated with different breeding habitats of dengue vector mosquitoes Aedes (Ae.) aegypti. and Ae. albopictus and to identify any parasitic, epibiont, pathogenic, competitive or predatory species.

Methods:

Sampling was performed from a variety of breeding habitats using dipping, pipetting and siphoning techniques. Microbiota in water samples were preserved using Rose Bengal solution and Lugol's iodine, and were identified. Live samples of microbiota were kept under laboratory conditions to observe any pathogenic or parasitic microbiota interacting with larvae.

Results:

A total of eleven microbiota species (Canthocamptus staphylinus, Canthocamptus microstaphylinus, Parastenocaris brevipes, Lepadella ovalis, Lepadella patella, Rotatoria rotatoria, Rotatoria macrura, Asplanchna brightwelli, Trichocerca rattus, Euglena variabilis, and Flagilaria capucina) belonging to four (4) phyla (Arthropoda, Rotifera, Euglenozoa, and Ochrophyta) and 8 microbiota species belonged to four phyla (Arthropoda, Rotifera, Euglenozoa, and Ochrophyta) were identified from Ae. aegypti and Ae. albopictus breeding habitats respectively. There was a higher percentage (54.54%) of larval habitats positive for the secondary vector Ae. albopictus than through the primary vector Ae. aegypti in the Gampola urban area indicating higher possibility of transmitting the dengue virus through the secondary vector. However, no pathogenic or parasitic ciliates on mosquito larvae were encountered in the present study. Those findings may be due to sampling maingly from temporary container-type breeding habitats.

Conclusions:

The relative distribution of microbiota associated with mosquito species differed significantly among Ae. aegypti and Ae. albopictus. The overall findings of this study could help in implementing novel eco-friendly vector-control strategies in the study area.
Clinical profile, etiology, management and outcome of empyema thoracis associated with COVID-19 infection: A systematic review of published case reports
Authors: Kamal Yasser Ali , Abdel-Gaber Seham Abdelwakeel
Published: September 2023

Objective:

To explore the clinical features, diagnosis, etiology, treatment, and outcomes of COVID-19 related empyema.

Methods:

Using PRISMA statement, a systematic search of relevant case reports published between December 2019 and April 2023 was performed through seven databases. The collected data included demographics, clinical manifestations, diagnostic findings, treatment, and outcomes.

Results:

Thirty-six case reports were identified with 43 cases of empyema. The included cases had a median age of 55 years (range: 12-78 years) and 79.1% (34/43) were males. The majority of cases presented during hospitalization for management of acute COVID-19 infection (29/43, 67.4%) and Charlson comorbidity index <3 (40/43, 93.0%). Pseudomonas aeruginosa was the most commonly isolated microorganism from the pleural fluid (9/43, 20.9%) and 16.3% of the cases (7/43) had polymicrobial infections. Chest drainage was performed in all cases while surgery was indicated in 24 cases (55.8%). The most common complication of COVID-19-related empyema was broncho-pleural fistula (2/43, 4.7%). The mortality rate was 23.3% (10/43). Sepsis and/or multi-organ failure were the most commonly reported causes of death. On univariate analysis, no statistically significant risk factor for mortality was identified.

Conclusions:

COVID-19-associated empyema has a variety of predisposing factors, time of presentation, clinical features, and causative organisms. Invasive or minimally invasive surgical procedures are performed more frequently than isolated chest drainage. Empyema in COVID-19 patients worsens their prognosis and can lead to serious complications.
Cutaneous anthrax associated with facial palsy: A case report
Authors: Ghafouri Majid , Mojtabaei Seyed Mehran , Shokri Azar
Published: September 2023

Rationale:

Anthrax is a zoonotic disease caused by spores of Gram-positive Bacillus anthracis, commonly affects mammals and in rare cases birds. Human infection occurs accidentally through direct or indirect exposure to animal or their products.

Patient concerns:

A 63-year-old man was referred to our hospital with flu-like symptoms and severe swelling and redness on the face, the roof of the mouth, and nostrils. He had a history of direct contact with a slaughtered mutton two days ago. He declared controlled diabetes, hypertension, hypertriglyceridemia, and heart failure. Lungs were normal in lung high resolution CT, but multiple lymphadenopathies were seen in the mediastinum. Bilateral axillary lymphadenopathy with a maximum sad of 23 mm and pleural effusion on the right side was observed. CT scan of the nose and sinuses showed an increased density of polyps in the left maxillary sinus. Slides were prepared from the patient's lesions and examined under a light microscope. Bacillus shape with Streptococcus bacteria was seen.

Diagnosis:

Anthrax co-infection with herpes systemic virus and Streptococcus pyogenes.

Interventions:

Multidrug therapy started with appropriate antibiotics.

Outcomes:

The symptoms of the patient gradually disappeared. The patient was discharged without any complications.

Lessons:

Cutaneous anthrax in endemic areas in patients with skin presentations and a history of contact with infected animals or products should be considered a differential diagnosis. This is more important in mixed infections where the main cause of the problem may be hidden.
Clinical characteristics and outcomes of nosocomial COVID-19 in Turkey: A retrospective multicenter study
Authors: Yıldırım Süleyman , Yılmaz Celalettin , Polat Gülru , Baris Serap Argun , Başyiğit İlknur , Kaya İlknur , Anar Ceyda , Bozkurt Mihriban , Baykal Hüsnü , Dirol Hulya , Ozbey Gamzenur , Ozsari Emine , Cireli Emel , Çırak Ali Kadri , Tatar Dursun , Gayaf Mine , Karaoglanoglu Selen , Aydin Yener , Eroglu Atilla , Olçar Yıldız , Yıldırım Berna Botan , Gürsoy Bengül , Yılmaz Deniz Demir , Niksarlioglu Elif Yelda Ozgun , Eren Ramazan , Erdem Ayşegül Tomruk , Tor Müge Meltem , Fakili Fusun , Çolak Mustafa , Erçelik Merve , Tabaru Ali , Ediboglu Özlem
Published: September 2023

Objective:

To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during the vaccination period nationwide in Turkey.

Methods:

COVID-19 patients followed in the pandemic services across Turkey between January 1, 2021, and March 31, 2022 were investigated retrospectively. Nosocomial COVID-19 was defined as a patient neither diagnosed with COVID-19 nor suspected COVID-19 at the hospital admission and was confirmed COVID-19 ≥5 days after hospital admission. The primary outcome of this study was in-hospital mortality; demographic features and vaccination status was compared between survivors and non-survivors.

Results:

During the study period, 15 573 COVID-19 patients were followed in 18 centers and 543 (3.5%) patients were nosocomial COVID-19. Most patients with nosocomial COVID-19 (80.4%) were transferred from medical wards. 162 (29.8%) of the patients with nosocomial COVID-19 admitted to the intensive care unit due to disease severity and 138 (25.4%) of the patients died during hospital stay. Advanced age (≥65 years) and number of comorbid diseases (≥2) was found to be associated with mortality in nosocomial COVID-19 (OR 1.74, 95% Cl 1.11-2.74 and OR 1.60, 95% Cl 1.02-2.56, respectively). Vaccination was associated with survival in nosocomial COVID-19 (OR 0.25, 95% Cl 0.16-0.38).

Conclusions:

Patients with nosocomial COVID-19 had increased admission to intensive care units and higher mortality rate. Vaccination can decrease the in-hospital mortality rate.
An In vitro Comparison of Retention of Provisional Crowns Cemented with Provisional Cement Enriched with Three Different Additives
Authors: Joshi Ravi , Shah Dipti S , Vaishnav Kalpesh , Patel Aneri , Patel Manish , Agnihotri Radhika
Published: September 2023

Introduction:

Dental caries remains a constant problem in clinical practice. The rates of recurrent caries around long-term provisional restorations may be even higher due to poor marginal adaptation and less stable materials. Since provisional crowns luted with provisional cement are susceptible to bacterial infiltration and caries, antibacterial and anticariogenic agents have been added to provisional cement, and retention of the provisional crown has been evaluated in this study.

Materials and Methods:

Ten extracted maxillary first premolar teeth were selected. Standardised tooth preparation was done. A total of 40 provisional crowns were fabricated using tooth-coloured auto-polymerising acrylic resin. The prepared provisional crowns were divided into four groups of 10 crowns each. Crowns were cemented on the prepared teeth after enriching with the three solutions individually. All specimens were stored in 100% humidity at 37°C for 1 h, thermocycler 100 times between 5°C and 55°C with a dwell time of 10 s and then stored at 100% humidity at 37°C. Cemented crowns were subjected to tensile dislodgement force using a universal testing machine with a crosshead speed of 5 mm/min.

Results:

Provisional cement enriched with Profluorid Varnish has shown properties of the highest tensile dislodgement force, with chlorhexidine-reduced retention.

Conclusion:

The present study concluded that Profluorid Varnish, as an additive in non-eugenol provisional cement (Provicol), is more effective in increasing retention.
Challenges and Barriers in Primary Mental Health Services in Saudi Arabia: A Narrative Review
Authors: Alshahrani Saad Shebnan , Alrajhi Mahdi Mohammed , Alshehri Mohammed Ahmad , Alotaibi Faris Mazyaed , Altwerqe Mayada Saleh
Published: September 2023

Multiple individuals around the world endure diagnosed or undiagnosed mental health issues. There is a growing recognition of the significance of mental health as a primary cause of disability with substantial effects on daily functioning. Approximately 10% of those needing assistance or treatment obtain the required assistance. Primary healthcare centres are the backbone of any nation's healthcare system because they provide the primary access point to treatment, illness prevention and an enhanced quality of life. They have the potential to boost the level of quality and productivity within the healthcare system, but still, many experience several barriers while trying to approach these services. Thus, this review discusses the various reasons challenging access to mental health services from primary care in Saudi Arabia.
Aripiprazole “Induced” and Aripiprazole “Worsened” Parkinsonism
Authors: Sharma Nagashree V , Shetty Kuldeep S
Published: September 2023

Aripiprazole, a novel neuroleptic and dopamine system stabilizer, is hailed as 3rd generation neuroleptic by some and claimed to have partial agonistic activity at D2 receptors (D2R), distinguishing it from other antipsychotics-D2 dopamine receptor antagonists. Many studies have extensively described extrapyramidal syndrome (EPS) profiles of earlier atypical neuroleptics including clozapine, quetiapine, olanzapine, ziprasidone, and risperidone. Despite the claimed D2R agonistic mechanism, EPS due to aripiprazole is sporadically reported – here below we report two such cases across two different baselines. One in a patient with no baseline Parkinsonism, another in a patient with well controlled Parkinson’s disease.
T- and B-cell Immune Response to COVID Vaccination in Liver Transplant Recipients Based on Interferon-gamma Release Assay and Serum Antibody Levels
Authors: DinuAbirami Premkumar , Panneerselvam Sugan , Mouleeswaran K. Sampath , Balajee Govindarao , Premkumar K. , Reddy Srinivas Mettu , Varghese Joy
Published: September 2023

Background and Aim:

This study aimed to assess T- and B-cell-mediated immune response following administration of two doses of COVID-19 vaccine in liver transplant (LT) recipients.

Subjects and Methods:

Twenty-eight liver transplant recipients and seven healthy volunteers without prior history of COVID-19 infection were enrolled. All individuals received two doses of COVID-19 vaccine (either Covishield or Covaxin), with the LT recipients receiving them at least 3 months after LT. The results of humoral (COVID-specific IgG) and cell-mediated immune response (interferon [INF]-gamma assay) following vaccination in the LT recipient group were compared with the control group.

Results:

Both LT recipients and control individuals developed COVID-specific antibodies following vaccination. The LT recipient group showed marginally higher INF-gamma levels with an average of 61.3 pg/ml compared to the control group 42.7 pg/ml (P = 0.051). There was no difference in the immunological response between patients who received the vaccination before or after 6 months posttransplant. There was no difference in response between the two vaccines.

Conclusion:

LT recipients mounted an immunological response comparable to the control group with both inactivated and viral vector vaccines for COVID-19, when vaccinated with an interval period of 3 months from transplant.
Boerhaave’s Syndrome: Better Late than Never – Delayed Management Using Endoscopic Over-the-Scope Clip
Authors: Sarangapani Arulprakash , George Tarun J , Malathi S
Published: September 2023

Boerhaave syndrome is spontaneous rupture of distal esophagus, caused by sharp increase intra esophageal pressure and negative intrathoracic pressure as with sudden forceful vomiting or retching. Classical Mackler clinical triad consists of vomiting, chest pain and subcutaneous emphysema. Mediastinal infection and sepsis are serious complications and can result in mortality upto 30 %, delay in treatment results in significant increase in mortality and morbidity. Early surgery is the best treatment option, surgery in elderly patients with multiple comorbid illness is challenging. Availability of full thickness closure devices using endoscopy like OTSC clips has a role in treating such group of patients. We present a elderly person who presented to us late and successfully managed endoscopically