bluuebunny/crossref_metadata_2025 huggingface dataset:
Astrocytes modulate sensory-evoked neuronal network activity
Authors: Lines Justin , Martin Eduardo D. , Kofuji Paulo , Aguilar Juan , Araque Alfonso
Published: July 2020

While neurons principally mediate brain function, astrocytes are emerging as cells with important neuromodulatory actions in brain physiology. In addition to homeostatic roles, astrocytes respond to neurotransmitters with calcium transients stimulating the release of gliotransmitters that regulate synaptic and neuronal functions. We investigated astrocyte-neuronal network interactions in vivo by combining two-photon microscopy to monitor astrocyte calcium and electrocorticogram to record neuronal network activity in the somatosensory cortex during sensory stimulation. We found astrocytes respond to sensory stimuli in a stimulus-dependent manner. Sensory stimuli elicit a surge of neuronal network activity in the gamma range (30–50 Hz) followed by a delayed astrocyte activity that dampens the steady-state gamma activity. This sensory-evoked gamma activity increase is enhanced in transgenic mice with impaired astrocyte calcium signaling and is decreased by pharmacogenetic stimulation of astrocytes. Therefore, cortical astrocytes respond to sensory inputs and regulate sensory-evoked neuronal network activity maximizing its dynamic range.
Direct visualization of irreducible ferrielectricity in crystals
Authors: Du Kai , Guo Lei , Peng Jin , Chen Xing , Zhou Zheng-Nan , Zhang Yang , Zheng Ting , Liang Yan-Ping , Lu Jun-Peng , Ni Zhen-Hua , Wang Shan-Shan , Van Tendeloo Gustaaf , Zhang Ze , Dong Shuai , Tian He
Published: July 2020

In solids, charge polarity can one-to-one correspond to spin polarity phenomenologically, e.g., ferroelectricity/ferromagnetism, antiferroelectricity/antiferromagnetism, and even dipole-vortex/magnetic-vortex, but ferrielectricity/ferrimagnetism kept telling a disparate story in microscopic level. Since the definition of a charge dipole involves more than one ion, there may be multiple choices for a dipole unit, which makes most ferrielectric orders equivalent to ferroelectric ones, i.e., this ferrielectricity is not necessary to be a real independent branch of polarity. In this work, by using the spherical aberration-corrected scanning transmission electron microscope, we visualize a nontrivial ferrielectric structural evolution in BaFe2Se3, in which the development of two polar sub-lattices is out-of-sync, for which we term it as irreducible ferrielectricity. Such irreducible ferrielectricity leads to a non-monotonic behavior for the temperature-dependent polarization, and even a compensation point in the ordered state. Our finding unambiguously distinguishes ferrielectrics from ferroelectrics in solids.
Waterborne pathogen monitoring in Jaipur, India reveals potential microbial risks of urban groundwater supply
Authors: Bivins Aaron , Lowry Sarah , Murphy Heather M. , Borchardt Mark , Coyte Rachel , Labhasetwar Pawan , Brown Joe
Published: July 2020

The Sustainable Development Goals require that 100 mL water samples contain no culturable E. coli to classify a water supply as “safely managed” from a microbial perspective. But small volume sampling is often insufficient for detecting microbial risks. We used culture-based measures of total coliforms and E. coli along with dead-end ultrafiltration (DEUF) and droplet digital PCR (ddPCR) to assess the microbial water quality of an urban water supply in Jaipur, India. Despite the absence of culturable E. coli in 90% of the 100 mL grab samples (n = 20) during the 10-day sampling period, we detected genes associated with protozoan and bacterial pathogens (Giardia, Cryptosporidium, and enterotoxigenic E. coli) in 3 DEUF samples of groundwater (n = 9; volume 59 to 122.4 liters). Of the three groundwater samples positive for waterborne pathogens, two were associated with 100 mL grab samples that were negative for culturable E. coli. Methods with improved analytical sensitivity, such as DEUF and ddPCR, can detect evidence of pathogens in drinking water supplies and supplement conventional culture-based methods to better inform pathogen-specific risk assessment and management.
Author Correction: Similar levels of emotional contagion in male and female rats
Authors: Han Yingying , Sichterman Bo , Carrillo Maria , Gazzola Valeria , Keysers Christian
Published: July 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Egg size and fecundity of biannually spawning corals at Scott Reef
Authors: Foster Taryn , Gilmour James
Published: July 2020

Egg size and fecundity are often used as proxies for coral reproductive success and health. The amount of energy a coral invests in reproduction reflects its environmental conditions during gametogenesis. Additionally, assuming resources for reproduction are limited, it is thought that an increase in egg size should result in a decrease in the number of eggs produced i.e. investing in many small eggs or fewer larger eggs. The biannually spawning populations of Scott Reef offer a unique opportunity to compare the egg size and polyp fecundity of corals exposed to different environmental conditions during gametogenesis, prior to spawning in autumn (March) and spring (October). In this study, we investigated the relationship between egg size and polyp fecundity within and between seven Acropora species from 2008 to 2010. We also quantified the fecundity and egg size of four Acropora species that spawn during both autumn and spring (2008–2010). We found no seasonal variability in egg size and fecundity in the species studied here, possibly as a result of a summer light regime being impacted by high cloud cover in cyclone season. There was high natural variability and no apparent trade-off between egg size and fecundity, both within and between each species. These findings challenge the assumption that egg size and fecundity are negatively correlated, or that a simple, energetically constrained trade-off exists between the two.
Trajectory analysis quantifies transcriptional plasticity during macrophage polarization
Authors: Liu Serena X. , Gustafson Heather H. , Jackson Dana L. , Pun Suzie H. , Trapnell Cole
Published: July 2020

In recent years, macrophages have been shown to be tremendously plastic in both in vitro and in vivo settings; however, it remains unclear whether macrophages retain any persistent memory of past polarization states which may then impact their future repolarization to new states. Here, we perform deep transcriptomic profiling at high temporal resolution as macrophages are polarized with cytokines that drive them into “M1” and “M2” molecular states. We find through trajectory analysis of their global transcriptomic profiles that macrophages which are first polarized to M1 or M2 and then subsequently repolarized demonstrate little to no memory of their polarization history. We observe complete repolarization both from M1 to M2 and vice versa, and we find that macrophage transcriptional phenotypes are defined by the current cell microenvironment, rather than an amalgamation of past and present states.
Association of dietary patterns with serum phosphorus in maintenance haemodialysis patients: a cross-sectional study
Authors: Khor Ban-Hock , Sualeheen Ayesha , Sahathevan Sharmela , Chinna Karuthan , Gafor Abdul Halim Abdul , Bavanandan Sunita , Goh Bak-Leong , Morad Zaki , Daud Zulfitri Azuan Mat , Khosla Pramod , Wang Angela Yee-Moon , Karupaiah Tilakavati ,   PaTCH Investigators, Bee Boon Cheak , Ahmad Ghazali , Lim Soo Kun , Wahab Mohammad Zaimi Abdul , Visvanathan Ravindran , Yahya Rosnawati
Published: July 2020

Sources of dietary phosphate differentially contribute to hyperphosphatemia in maintenance haemodialysis (MHD) patients. This cross-sectional study in Malaysia investigated association between dietary patterns and serum phosphorus in MHD patients. Dietary patterns were derived by principal component analysis, based on 27 food groups shortlisted from 3-day dietary recalls of 435 MHD patients. Associations of serum phosphorus were examined with identified dietary patterns. Three dietary patterns emerged: Home foods (HFdp), Sugar-sweetened beverages (SSBdp), and Eating out noodles (EO-Ndp). The highest tertile of patients in HF (T3-HFdp) pattern significantly associated with higher intakes of total protein (p = 0.002), animal protein (p = 0.001), and animal-based organic phosphate (p < 0.001), whilst T3-SSBdp patients had significantly higher intakes of total energy (p < 0.001), inorganic phosphate (p < 0.001), and phosphate:protein ratio (p = 0.001). T3-EO-Ndp patients had significantly higher intakes of total energy (p = 0.033), total protein (p = 0.003), plant protein (p < 0.001), but lower phosphate:protein ratio (p = 0.009). T3-SSBdp patients had significantly higher serum phosphorus (p = 0.006). The odds ratio of serum phosphorous > 2.00 mmol/l was significantly 2.35 times higher (p = 0.005) with the T3-SSBdp. The SSBdp was associated with greater consumption of inorganic phosphate and higher serum phosphorus levels.
Highly nonlinear magnetoelectric effect in buckled-honeycomb antiferromagnetic Co4Ta2O9
Authors: Lee Nara , Oh Dong Gun , Choi Sungkyun , Moon Jae Young , Kim Jong Hyuk , Shin Hyun Jun , Son Kwanghyo , Nuss Jürgen , Kiryukhin Valery , Choi Young Jai
Published: July 2020

Strongly correlated materials with multiple order parameters provide unique insights into the fundamental interactions in condensed matter systems and present opportunities for innovative technological applications. A class of antiferromagnetic honeycomb lattices compounds, A4B2O9 (A = Co, Fe, Mn; B = Nb, Ta), have been explored owing to the occurrence of linear magnetoelectricity. From our investigation of magnetoelectricity on single crystalline Co4Ta2O9, we discovered strongly nonlinear and antisymmetric magnetoelectric behavior above the spin-flop transition for magnetic fields applied along two orthogonal in-plane directions. This observation suggests that two types of inequivalent Co2+ sublattices generate magnetic-field-dependent ferroelectric polarization with opposite signs. The results motivate fundamental and applied research on the intriguing magnetoelectric characteristics of these buckled-honeycomb lattice materials.
Substantial blue carbon in overlooked Australian kelp forests
Authors: Filbee-Dexter Karen , Wernberg Thomas
Published: July 2020

Recognition of the potential for vegetated coastal ecosystems to store and sequester carbon has led to their increasing inclusion into global carbon budgets and carbon offset schemes. However, kelp forests have been overlooked in evaluations of this ‘blue carbon’, which have been limited to tidal marshes, mangrove forests, and seagrass beds. We determined the continental-scale contribution to blue carbon from kelp forests in Australia using areal extent, biomass, and productivity measures from across the entire Great Southern Reef. We reveal that these kelp forests represent 10.3–22.7 Tg C and contribute 1.3–2.8 Tg C year−1 in sequestered production, amounting to more than 30% of total blue carbon stored and sequestered around the Australian continent, and ~ 3% of the total global blue carbon. We conclude that the omission of kelp forests from blue carbon assessments significantly underestimates the carbon storage and sequestration potential from vegetated coastal ecosystems globally.
Soluble Klotho, a biomarker and therapeutic strategy to reduce bronchopulmonary dysplasia and pulmonary hypertension in preterm infants
Authors: Batlahally Sunil , Franklin Andrew , Damianos Andreas , Huang Jian , Chen Pingping , Sharma Mayank , Duara Joanne , Keerthy Divya , Zambrano Ronald , Shehadeh Lina A. , Martinez Eliana C. , DeFreitas Marissa J. , Kulandavelu Shathiyah , Abitbol Carolyn L. , Freundlich Michael , Kanashiro-Takeuchi Rosemeire M. , Schmidt Augusto , Benny Merline , Wu Shu , Mestan Karen K. , Young Karen C.
Published: July 2020

Preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) have accelerated lung aging and poor long-term outcomes. Klotho is an antiaging protein that modulates oxidative stress, angiogenesis and fibrosis. Here we test the hypothesis that decreased cord Klotho levels in preterm infants predict increased BPD–PH risk and early Klotho supplementation prevents BPD-like phenotype and PH in rodents exposed to neonatal hyperoxia. In experiment 1, Klotho levels were measured in cord blood of preterm infants who were enrolled in a longitudinal cohort study. In experiment 2, using an experimental BPD–PH model, rat pups exposed to room air or hyperoxia (85% O2) were randomly assigned to receive every other day injections of recombinant Klotho or placebo. The effect of Klotho on lung structure, PH and cardiac function was assessed. As compared to controls, preterm infants with BPD or BPD–PH had decreased cord Klotho levels. Early Klotho supplementation in neonatal hyperoxia-exposed rodents preserved lung alveolar and vascular structure, attenuated PH, reduced pulmonary vascular remodeling and improved cardiac function. Together, these findings have important implications as they suggest that perinatal Klotho deficiency contributes to BPD–PH risk and strategies that preserve Klotho levels, may improve long-term cardiopulmonary outcomes in preterm infants.
A putative UDP-glycosyltransferase from Heterorhabditis bacteriophora suppresses antimicrobial peptide gene expression and factors related to ecdysone signaling
Authors: Kenney Eric , Yaparla Amulya , Hawdon John M. , O’Halloran Damien M. , Grayfer Leon , Eleftherianos Ioannis
Published: July 2020

Insect pathogens have adopted an array of mechanisms to subvert the immune pathways of their respective hosts. Suppression may occur directly at the level of host–pathogen interactions, for instance phagocytic capacity or phenoloxidase activation, or at the upstream signaling pathways that regulate these immune effectors. Insect pathogens of the family Baculoviridae, for example, are known to produce a UDP-glycosyltransferase (UGT) that negatively regulates ecdysone signaling. Normally, ecdysone positively regulates both molting and antimicrobial peptide production, so the inactivation of ecdysone by glycosylation results in a failure of host larvae to molt, and probably a reduced antimicrobial response. Here, we examine a putative ecdysteroid glycosyltransferase, Hba_07292 (Hb-ugt-1), which was previously identified in the hemolymph-activated transcriptome of the entomopathogenic nematode Heterorhabditis bacteriophora. Injection of recombinant Hb-ugt-1 (rHb-ugt-1) into Drosophila melanogaster flies resulted in diminished upregulation of antimicrobial peptides associated with both the Toll and Immune deficiency pathways. Ecdysone was implicated in this suppression by a reduction in Broad Complex expression and reduced pupation rates in r Hb-ugt-1-injected larvae. In addition to the finding that H. bacteriophora excreted-secreted products contain glycosyltransferase activity, these results demonstrate that Hb-ugt-1 is an immunosuppressive factor and that its activity likely involves the inactivation of ecdysone.
Strain-enhanced Dzyaloshinskii–Moriya interaction at Co/Pt interfaces
Authors: Deger Caner
Published: July 2020

The interfacial Dzyaloshinskii–Moriya interaction (DMI) is an essential ingredient for stabilizing chiral spin configurations in spintronic applications. Here, via first-principles calculations, we reveal the influence of lattice strain on DMI in Co/Pt interface. We observed a considerable enhancement for a certain lattice strain. Furthermore, a direct correlation is established between the DMI and interlayer distances dominated by the strain, which is attributed to a hybridization of electronic orbitals. This hybridization has also been presented as the microscopic origin of the interfacial DMI. We anticipate that our predictions provide new insights into the control of interfacial DMI for skyrmion-based spintronic devices.
High PD-L1 expression is associated with therapeutic response to pembrolizumab in patients with advanced biliary tract cancer
Authors: Ahn Soomin , Lee Jong-chan , Shin Dong Woo , Kim Jaihwan , Hwang Jin-Hyeok
Published: July 2020

Pembrolizumab appears promising for patients with programmed cell death ligand-1 (PD-L1)-positive solid tumors. However, data on immunotherapy for biliary tract cancers (BTC) are limited. We aimed to investigate the predictive value of PD-L1 expression as an immunotherapeutic biomarker in BTC. Patients with advanced BTC (n = 175) were screened for PD-L1 expression using PharmDx assay and microsatellite instability (MSI) status. Of the total of 175 patients, 125 (71%) showed tumoral PD-L1 positivity (≥ 1%) while only two (2/142, 1.4%) showed MSI-High. Among 175 patients, 26 patients were treated with pembrolizumab as a second-line therapy, and tumor response was evaluated. Separating these patients into two groups by PD-L1 expression (high [≥ 50%] vs. low [< 50%]), overall response rate was 23% (56% [5/9] in high PD-L1 group vs. 6% [1/17] in low PD-L1 group, P = 0.004). Disease control rate was also higher in high PD-L1 group (78% vs. 35%, P = 0.019). The six responders showed median progression-free survival of 5.8 months after starting pembrolizumab, and none of them was MSI-High. High PD-L1 expression was associated with a better response to pembrolizumab. PD-L1 expression can potentially serve as an alternative predictive biomarker for pembrolizumab therapy in advanced BTC.
Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway
Authors: Assani Israa , Du Ying , Wang Chun-Gu , Chen Lei , Hou Pei-Lei , Zhao Shi-Feng , Feng Yan , Liu Ling-Fei , Sun Bo , Li Yan , Liao Zhi-Xin , Huang Ri-Zhen
Published: July 2020

A novel and ten known diterpenoids were isolated from the ethanolic crude extract of the fresh tubers of Sagittaria trifolia L. Compound 11 exhibited strong inhibitory activity on Hct-116 cancer cells by blocking the NF-κB signaling pathway.
Capabilities of automated LA-ICP-TOFMS imaging of geological samples
Authors: Neff Christoph , Keresztes Schmidt Peter , Garofalo Paolo S. , Schwarz Gunnar , Günther Detlef
Published: July 2020

A new software control system enables adaptable and task-specific ablation modes for LA-ICP-TOFMS imaging.
Mechanism of visible photon absorption: unveiling of the C3N4–ZnO photoactive interface by means of EPR spectroscopy
Authors: Cerrato Erik , Paganini Maria Cristina
Published: July 2020

This work unambiguously describes the direct-Zscheme governing the charge carrier separation induced by visible light of the C3N4–ZnO heterojunction.
Effect of access resistance on the experimentally measured temperature–carrier mobility dependence in highly-crystalline DNTT-based transistors
Authors: Wang Qijing , Jiang Sai , Shi Yi , Li Yun
Published: July 2020

The carrier mobility–temperature dependence obtained from DNTT OFETs can be tuned by the access resistance and the molecular packing in bulk regime.
UV–O3 treated annealing-free cerium oxide as electron transport layers in flexible planar perovskite solar cells
Authors: Pang Aiying , Li Jinlong , Wei Xiao-Feng , Ruan Zhi-Wu , Yang Ming , Chen Zhong-Ning
Published: July 2020

UV–O3 treated annealing-free cerium oxide (CeOx) is used as the electron transport layers of flexible planar perovskite solar cells to achieve the highest PCE of 14.63%. The devices retained ca. 90% efficiency of the initial value after recovery from 500 bending cycles at r = 15 mm.
Selectivity control in thiol–yne click reactions via visible light induced associative electron upconversion
Authors: Burykina Julia V. , Shlapakov Nikita S. , Gordeev Evgeniy G. , König Burkhard , Ananikov Valentine P.
Published: July 2020

An associative electron upconversion is proposed as a key step determining the selectivity of the thiol–yne coupling.
In situ tissue pathology from spatially encoded mass spectrometry classifiers visualized in real time through augmented reality
Authors: Woolman Michael , Qiu Jimmy , Kuzan-Fischer Claudia M. , Ferry Isabelle , Dara Delaram , Katz Lauren , Daud Fowad , Wu Megan , Ventura Manuela , Bernards Nicholas , Chan Harley , Fricke Inga , Zaidi Mark , Wouters Brad G. , Rutka James T. , Das Sunit , Irish Jonathan , Weersink Robert , Ginsberg Howard J. , Jaffray David A. , Zarrine-Afsar Arash
Published: July 2020

Integration between a hand-held mass spectrometry desorption probe based on picosecond infrared laser technology (PIRL-MS) and an optical surgical tracking system demonstrates in situ tissue pathology from point-sampled mass spectrometry data.
Photothermal effect of carbon quantum dots enhanced photoelectrochemical water splitting of hematite photoanodes
Authors: Hu Xiaoqin , Huang Jing , Zhao Feifan , Yi Ping , He Bing , Wang Yang , Chen Tao , Chen Yihuang , Li Zhen , Liu Xueqin
Published: July 2020

The photothermal effect of CQDs is introduced to promote the bulk charge transport and surface oxidation kinetics of Co-Pi/CQDs/Fe2O3/TiO2 photoanodes simultaneously, resulting in a remarkably enhanced PEC water splitting performance.
Routes for advancing SnTe thermoelectrics
Authors: Chen Zhiyu , Guo Xuming , Zhang Fujie , Shi Qing , Tang Mingjing , Ang Ran
Published: July 2020

Effective strategies focusing on improving the thermoelectric performance of environment-friendly SnTe alloys.
Correction: A flexible, multifunctional, active terahertz modulator with an ultra-low triggering threshold
Authors: Ma He , Wang Yu , Rong Lu , Tan Fangrui , Fu Yulan , Wang Guang , Wang Dayong , Liu Kai , Fan Shoushan , Jiang Kaili , Zhang Xinping
Published: July 2020

Correction for ‘A flexible, multifunctional, active terahertz modulator with an ultra-low triggering threshold’ by He Ma et al., J. Mater. Chem. C, 2020, DOI: 10.1039/d0tc02446e.
Product Design for Reuse of Waste Construction Wood——Teapot Tray Design Practices
Authors: Liu Wenming , Cui Yingjie
Published: July 2020

By using waste construction wood as the main raw material, the design practice is based on increasing the storage function of the teapot tray. In the design of the product, we strive to show the unique texture of the waste construction wood. Structural design is based on tenon-and-mortise structure, convenient assembly and disassembly of products as design principles, easy replacement of parts and continuation of product life as design purpose, and teapot tray design through product modular design ideas. Modeling design combined with traditional cultural concepts to “turn waste into treasure.”
Environmental (Art) Design VS Interior and Spatial Design: A dialogue between Chinese and Italian design disciplines
Authors: Yang Yeqiu , Guerrini Luca
Published: July 2020

The relationship between China and Italy has ever been stronger for academic exchanges to flourish. Vital exchange of teachers and students among design universities has soared to paramount levels. With this, beginning in 2007, both Chinese and Italian higher education institutions have established the ‘double master’s degree programs in design’, with the corresponding degrees being ‘environmental (art) design’ and ‘interior and spatial design’ respectively. Meanwhile, there are great strides, followed by demands to strengthen the understanding of the respective cultures, language, and methods of both design institutions. This article aims to assist and facilitate a dialogue of understanding between the two design cultures by analyzing the current status and the evolution of their disciplines in both nations. This research may provide a common basis for the innovation in the field in both countries and contributing useful theoretical notions for the education of design.
A Spatiotemporal data acquisition and processing method for Ansai waist drum based on motion capture
Authors: Guo Ying , Wang Xupeng
Published: July 2020

In order to effectively promote the inheritance and preservation of the intangible cultural heritage project-Ansai waist drum. Based on motion capture systems, a spatiotemporal data acquisition and processing method is introduced in this works, which contains principles and specific methods for data acquisition and processing. Take a typical action as an example, the method is presented seriously, which refers to acquisition site, motion capture equipment, real-time acquisition, data output, post-processing software, as well as skeleton and excel data processing. Furthermore, the canonical motion data of Ansai waist drum also can be calculated by this method, and then used as the standard data for beginners. The method could be a reference for inheritance and preservation to sports and dance intangible cultural heritage projects.
Study on the Method of Calculating Temperature Rise of Transformer
Authors: Li Tao , Du Xiaoping , Sun Xuewu , Song Yuanyuan
Published: July 2020

The internal temperature of the transformer is a key parameter to measure the thermal state of the transformer. The service life of the transformer generally depends on the life of the insulating material, and high temperature is the main reason why cause insulation aging, this paper studies the temperature rise of transformer winding hot spot temperature for the key, using the neural network forecasting method, forecasts transformer winding hot spot temperature change rule, calculate the transformer internal temperature rise, provide the temperature of the scientific basis for the safe operation of the transformer.
Research on Multi-element Fusion of Equipment Fault Monitoring Based on Evidence Theory
Authors: ZHOU Quan , LIU Lan , CHENG Hao , FU Mian
Published: July 2020

The multi-information fusion method of health monitoring based on evidence theory is used to study the problem of equipment fault diagnosis. The multi-information of fault monitoring is fused by the evidence theory and the reliability of the relevant evidence can be judged according to the ambiguity and uncertainty of the fault monitoring signal. Also it can determine the importance and reliability of the evidence from different sources. The data from multi-information fusion has higher reliability and accuracy which provides more reliable data for fault diagnosis.
Design specification representation for intelligent product appearance design
Authors: Huicong Hu , Wen-Feng Lu
Published: July 2020

Traditional intelligent product design usually focuses on functional design, aiming to generate appropriate structures that would provide required functions. Design specifications are mainly formulized into technical descriptions or values that are related to certain functional or usability requirements. In today’s global market, to in-crease user satisfaction, the appearance design of a product become vital for users to make purchasing decisions. This is particularly true of today’s consumer products such as mobile phones, digital cameras, and other electronic products. In intelligent product appearance design, design specifications are merely described as basic geometric dimensions and types of surface materials. Additionally, the aesthetic considerations and emotional needs of product appearance are seldom discussed when establishing design specifications for product appearance design. In this regard, the objective of this study is to propose a design specification representation framework for intelligent product appearance design considering both emotional and aesthetic aspects. The framework be-gins to investigate user needs by acquiring user aesthetic experience. Based on the notion of aesthetic experience, a detailed representation model of appearance design specifications is provided for satisfying user emotional and aesthetic needs. Finally, a case study of the appearance design of digital cameras is provided to demonstrate the acquisition of user needs and establishment of design specifications based on the proposed framework.
Construction and Application of the Design Method of Cultural Products Based on the Meme of Liao dynasty ceramics
Authors: Zhu Yue , TENG Cheng-lein
Published: July 2020

A design method of one cultural product based on the meme of artifacts was constructed and applied to the development and design of cultural products. Firstly, the paper puts forward that the outer “tangible” level of the “spatial perspective” of culture corresponds to the dominant meme, as well as the mid “behavioral” level and Inner “intangible” level correspond to the hidden meme according to the theories of meme and the “spatial perspective” of culture. What’s more, the meme was extracted according to the appearance of Liao dynasty ceramics and related research literature. Secondly, based on the extracted meme of Liao dynasty ceramics, the design method of cultural products was constructed by applying the theoretical framework two orders of the signification of Roland Barthes Semiotics to explore the extended cultural meaning of meme and apply its translation to the design of cultural products. The design method of cultural products constructed by this Institute is more inclusive of the intrinsic level of artifacts than that in the past, which only created cultural products that focus on the physical representation of the visual elements. It is an attempt to provide designers of cultural products and students with design background with a design method of cultural products for reference.
Implementation of Smart Manufacturing Maturity Assessment Framework：A Socio-Technical Perspective
Authors: Yue Lei , Wang Zhou , Fang Yifang , Han Zhonghua
Published: July 2020

Smart manufacturing capability maturity assessment has been widely carried out in order to help enterprises to identify the direction and route of smart transformation by stationing in enterprises. However, many maturity models for industrial enterprises can not reflect their industrial realities more accurately. Therefore, the aim of this paper attempts to make the smart manufacturing maturity assessment operational, and implement a specific assessment framework based on an existing general conceptual framework. This implementation involved two top-down approaches that one is socio-technical system as a top-level design of factors, and the other is refining assessment domains based on lifecycle and activity models. Results of this implementation showed a two-dimensional assessment framework instance and collections of definitions for capability maturity levels. To conclude, this implementation may be a reference for work specification of smart manufacturing maturity assessment. Three possible future research in the area was suggested at last.
Design of Popular Science Toys Based on Children’s Growth Cognition Law
Authors: Gao Hong-he , Xing Xiao-cheng , Fu Jin-hua
Published: July 2020

China is a big consumer of toys. With the opening of the country’s two-child policy and parents pay more and more attention to children’s education, the toy market is becoming increasingly popular. Toys are important playmates in children’s growth and play an important role in children’s intellectual development and early education. However, at present, children’s toys are mostly educational toys, which only inspire children’s intelligence, stimulate children’s brain activity and develop children’s intelligence. However, systematic popular science toys for children are relatively lacking, and relevant research materials are also few, which do not play a good role in enlightening children’s popular science. According to the design principles and methods of children’s toys, aiming at the shortcomings of the existing popular science toys for children, through in-depth investigation and analysis of popular science toys for children, this paper organically combines children’s toys with popular science, and makes some design attempts. The aim is to change the current situation that many students have a certain fear of physics and chemistry in high school due to the lack of popular science knowledge in childhood.
Research on Fine-Grained Classification of Rumors in Public Crisis ——Take the COVID-19 incident as an example
Authors: Chen Shuaipu
Published: July 2020

[Purpose / Meaning] Rumors are frequent in the COVID-19 epidemic crisis. In order to unite the power of dispelling rumors of various media platforms to help to break the rumors in a timely and professional manner, this article has designed a new fine-grained classification of rumors about COVID-19 based on the BERT model. [Method / Process] Based on the rumor data of several mainstream rumor refuting platforms, the pre-training model of BERT was used to fine-tuning in the context of COVID-19 events to obtain the feature vector representation of the rumor sentence level to achieve fine-grained classification, and a comparative experiment was conducted with the TextCNN and TextRNN models. [Result / Conclusion] The results show that the classificationF1 value of the model designed in this paper reaches 98.34%, which is higher than the TextCNN and TextRNN models by 2%, indicating that the model in this paper has a good classification judgment ability for COVID-19 rumors, and provides certain reference value for promoting the coordinated refuting of rumors during the public crisis.
Product Design Decision Oriented by Hierarchical Relevance of User’s First Perceptual Demand
Authors: Wang Yi , Ding Zipei , Fan Sichao
Published: July 2020

User’s perceptual demands for products usually show “multi-dimensional, multi-level, dynamic, and ambiguous” features. Emotional words and phrases are often used by users to express their perceptual demands for products. In this paper, the dynamic intuitionistic fuzzy multi-attribute decision-making method is adopted to establish the hierarchy of demands. The correlation measure of intuitionistic fuzzy sets is used to calculate the correlation between the perceptual demand set and the semantic set with emotional expressions. Mapping the results to target users’ typical characteristics, we can acquire the users’ hierarchy of demands to designed products. Taking the design of a headset as the case, product perception evaluation experiments and relevant data analysis of 10 different design plans are carried out to clarify the ideal product’s “position” in the semantic space of typical user group. The hierarchy of perceptual demands of users to the headset is successfully established, which proved the feasibility of this method.
Study on user experience of airport rail to air Transfer Mode based on QFD and service design methods
Authors: Sun Shan , Ma Dongming , Qian Hao
Published: July 2020

Objective: To further perfect service design of “rail to air transfer” mode at Beijing Daxing Airport, optimize the transfer flow and improve passengers’ “door to door” transfer experience. Method: Quality function deployment (QFD) method was introduced into the optimization process of service design. Firstly, the user demand for current “rail to air transfer” mode was collected through questionnaire survey and interview method, followed by analysis and classification using KJ method, user demand weight was determined via analytic hierarch process (AHP) method, the correlation between user demand and design elements was quantitatively evaluated through QFD method, and house of quality (HOQ) was constructed to complete the transformation from user demand into design elements. In the end, service contact analysis was implemented according to obtained parameters, the suggestions for improvement were proposed and the service optimization blueprint was constructed. Conclusion: Starting from user demand, QFD method was integrated with service design to optimize and innovate the service design of the existing “rail to air transfer” mode at Daxing Airport. This study has provided a new strategy and method for improving transfer service and user experience.
The Professional Education Ecosystem of Industrial Design at Georgia Institute of Technology Based on SECI Model
Authors: Guo Xiaopeng , Xue Yanmin
Published: July 2020

The changes in international competitive environment and the adjustment of national industrial development strategy have put forward new requirements for the education of industrial design. Industrial design is the research on design knowledge. It includes systematic explicit knowledge and empirical tacit knowledge. The education of design is about the transfer and accumulation of this specialized knowledge. By using SECI model of knowledge transformation and creation proposed by Ikujiro Nonaka and others, this article analyzes four processes of knowledge transformation, the platform of knowledge transformation (“Ba”) and knowledge assets. It studies the educational mode of the School of Industrial Design at Georgia Institute of Technology. From basic professional education, to department-level studio courses and university-level laboratory research, to the completion of industrial design education, professional knowledge is built up through the whole process, thus a virtuous cycle of professional education ecosystem is established. It is hoped this will bring useful experience to the education of industrial design in China.
Research and Application of Ankle Morphological Changes and Classification
Authors: Zhang Chunqiang , Ji Xiaomin , Xue Yanmin , Hu Gang
Published: July 2020

Because of the motion of ankle joint, the surface morphological changes. The relevant products including ankle brace, ankle boot, etc. with both important protective effect on ankle and comfort should be designed to match the ankle varies states. The samples data with 15° plantar flexion, 40° dorsiflexion and neutral position of lower limbs(N=105) were scanned. This study analyzed the feature of the ankle morphological changes and divided it into four parts: anterolateral (I), posterolateral (II), posteromedial (III) and anteromedial (IV). The anterior and posterior parts had large contraction and expansion during plantar flexion and dorsiflexion motions. The medial and lateral parts of ankle shape were asymmetric, but had equal skin areas. Therefore, the area of the entire ankle surface remained almost the same when morphological changes. We unified the data of the models and measured the distances of characteristic points. According to the main dimensions, the ankles were classified into 17 groups. The rigid brace design was taken as an example to fit mass ankles. It showed a great statistical comfort degree in total by the user experience and evaluation. The method combining with features of ankle morphological changes and shape classification was proved to be effective for the ankle related products design to fit mass ankles.
Perceptual design method research in product design
Authors: Liu Wenming , Cui Hao
Published: July 2020

On the purpose of deepening method research of perceptual analysis, based on the description of the relationship between perceptual design and rational design, the importance of perceptual design in modern product design is clarified. To strengthen the emotional expression of the product, the study focuses on sort perceptual design method with the background of perceptual design internalization and equivalent theory. Taking the perceptual design as the bond, how the method located sensibility in product design is analyzed. By taking advantage of formal beauty rule, more perceptual elements are added into product design to summarize the method and principle based on the product perceptual design.
Research on the Application of ASMR in the Development and Design of Sleeping Products
Authors: Wang Miao , Li Bo
Published: July 2020

Sleep is an important basis to keep human’s health and physiological activity. But nowadays, sleep disorders, depression, anxiety has become a social problem. Both young and middle-aged people face frequent health problems. In order to improve the sleep quality of the urban population and effectively alleviate the influence of a bad mood before sleep on sleep quality. Through the use of Autonomous Sensory Meridian Response (AMSR) induces a sensory phenomenon to help sleep, combine this new experience with the design, according to the features of this sensory phenomenon formulate a sleeping product scheme, discovering the new way to help to ease symptoms of sleep disorders. Through comparative experiments, test the sleep time of the target population, it is utilized to compare the sleeping time of the subjects after the application of the product. Analyse the feasibility and effectiveness of the product. The result showed that apply this product, 66% of the subjects reported that it was good to sleep, the validity of this method is proved.
Optimised analysis of community medical APP user experience under cognitive load theory
Authors: Han Peng , Xu Liyuan , Lv Xiaochen
Published: July 2020

Based on community medical APP as the carrier, this paper studies the emotional and experiential process of community doctors using mobile community medical APP under different cognitive loads, and puts forward the improvement of product optimization. Firstly, based on the cognitive load theory, objective user data is obtained through cognitive load control experiments on target users. Second, ask the target user to fill in the Positive and Negative Affect Scale and System Usability Scale to obtain subjective user data. Finally, analyze the user’s subjective and objective data. Based on the analysis of experimental results and user observation, the improvement strategy is proposed to reduce the barriers to community doctors learning and using community medical apps.
Early Findings from Hospice Service Design
Authors: Zhao Yang
Published: July 2020

In the face of the increasing global trend of aging, hospice care has become a project that cannot be ignored in the public health field. There are many homogeneous designs with the connotation of hospice service, but clear theoretical and design principles are still vacant. This article introduces the concept of hospice service design and the development status of the current era. Focusing on the difficulties occur in research and practice process, making a brief outlook on the future development of hospice service design.
Research on product innovation design methods
Authors: Zhang Weiguo , Shu Jianyao , Hu Xitong , Mei Yun
Published: July 2020

When the prehistoric man began to pick up stones, wood and other materials to make tools, we can confirm that creativity is not only the designer’s personal patent but a natural gift of humanity. As product designers, we must have more creativity than ordinary people. By analyzing a large number of actual design works and award-winning works in international competitions for many years, the author summarizes the similarities of creative design and explores the application of innovative product design methods in design.
The preliminary study on the application of modern advanced processing technique in non-legacy cultural and creative product design-- Taking Wuhu iron painting as an example
Authors: Tiancheng Zhang , Tieyi Chu
Published: July 2020

In order to improve the production efficiency of traditional non-legacy cultural heritages and create non-legacy cultural and creative products in line with modern aesthetics, the paper combines traditional non-legacy cultural heritages manufacturing technique and modern advanced processing technique, which is conducive to improve the design of traditional techniques of Wuhu iron painting. First of all, this paper analyzes the connotation of traditional non-legacy cultural heritage technology, the categories of modern advanced processing technique and the traditional forging technique of Wuhu iron painting, and introduces the strategy and development history of traditional non-legacy cultural heritage manufacturing technique. Taking Baogong cultural and creative product design as an example, this paper innovates the processing technique of iron painting through cutting and processing, and the design theme is fully realized in the innovative iron painting, which to a certain extent realizes the unity of technique and art, and shows the effectiveness and practicability of modern advanced processing technique in non-legacy cultural and creative product design.
Symbol Condensation and Design of Cultural & Creative Products in Regional Cultural Context
Authors: Wang Yi , Fan Sichao , Shi Meng
Published: July 2020

The attractiveness of cultural & creative products on spreading and “recurring” regional culture is the key to the shaping of urban culture. In this paper, starting from the differences of regional cultural contexts, we discussed the explicit culture and implied culture in cultural symbols and put forward new ideas on regional cultural context reconstruction and symbol condensation and conversion. The symbolic design of cultural & creative products in the cultural context of Spring Festival education in Xi’an was taken as an example here, and the method proposed herein was further clarified through cultural context reconstruction of “Yanta Praying” activity and symbolic design of educational & cultural products.
Research on design of Tibetan cultural and creative products based on prototype theory
Authors: Shutao Zhang , Zonglin An , Pengfei Su , Jianning Su
Published: July 2020

Aiming at the problems of homogeneity, simplification and low cultural recognition of Tibetan cultural and creative products, design and application research are carried out in combination with prototype theory. Firstly, we determine the target product through fieldwork, and analyze the existing products in the market. Then through the analysis of Tibetan culture, using product semantic methods, we extract the pattern elements that match the semantic of the target product, and determine the design prototype. Finally, combining the prototype theory, we analyse of the design prototype to inspire the design, complete the innovative design of the product. Practice has shown that the use of prototype theory for product design can accurately identify Tibetan cultural symbols and excavate cultural connotations to promote the spread and development of Tibetan culture.
Analysis of Image Historical Data of Wooden Sculptures of Su-style Furniture in Ming and Qing Dynasties
Authors: Gao Weixia , Guo Yuliang
Published: July 2020

In the Ming and Qing dynasties, the image materials of woodcarving furniture in Suzhou area are as important as the actual furniture, which are also valuable material information on the living customs of Suzhou in the Ming and Qing dynasties. From the perspective of imageology, this article analyzes the shape, category, style and other representative works of Su-style furniture’s woodcarving visual image, hoping to provide a reference for the research and design of regional furniture carving.
Research on the Evolution of Traditional Fish Pattern and Its Application in Modern Design
Authors: Yin Fan , Shi Jian , Ma Xiaoqing
Published: July 2020

The fish pattern has a long history and it is one of the earliest traditional decorative patterns in China. The important reason for the continuous inheritance and development of fish patterns lies in its unique shape and diversified cultural connotation. Regarding the cultural meaning as the starting point, this paper makes a comprehensive and systematic discussion on the development, modeling and cultural meaning of fish patterns, and further probes into the development and application of the fish pattern in modern design from a unique perspective.
1500 Euro Preisgeld
Authors: Schäfer Christian
Published: July 2020

Die Thieme Gruppe schreibt im Jahr 2020 wieder den Förderpreis Nephrologische Pflege aus und stiftet das Preisgeld von 1500 Euro.