bluuebunny/crossref_metadata_2025 huggingface dataset:
ПРОБЛЕМА НАУКОВОЇ ОБ’ЄКТИВНОСТІ І ТЕОРІЯ ПСИХОАНАЛІТИЧНОГО ЛІКУВАННЯ
Authors: Когут Гайнц
Published: August 2024

Анотація. У третій главі книги «Як лікує аналіз?» 1984 р. Гайнц Когут розглядає проблему наукової об’єктивності в психоаналізі. Автор стверджує, що наукову роботу, включаючи роботу в психоаналізі, потрібно оцінювати з огляду на її пояснювальну силу, однак водночас наголошує, що в психології складних психічних станів об’єктивної істини не існує, тож ми повинні завжди враховувати оцінку спостерігача. Вимога нейтральності психоаналітика в умовах психоаналізу також не є реалістичною: на думку Когута, клінічна ситуація є повною протилежністю до нейтральної. Автор також торкається внесків різних шкіл думок: він уважає, що їхні наукові спостереження не тільки зображають світ, а й грають роль у його формуванні. Когут підкреслює важливість теорії, якої дотримується спостерігач, адже це впливає не лише на те, що він бачить у психоаналітичному процесі та його результатах, а й на те, що є для нього значущим, а що – незначним. Цікавим є проведення автором паралелі між традиційним аналізом і аналітичною Селф-психологією та між фізикою Ньютона і фізикою Планка. Автор також приділяє увагу тому, що не існує одного виду здорового селф (self) та не існує єдиного аналітичного шляху до зцілення. Однак, порівнюючи теоретичну рамку традиційного психоаналізу, де внутрішні конфлікти розглядаються як такі, що мають згубний вплив на творчо-продуктивну діяльність, та рамку Селф-психології, Когут обґрунтовує, що, відповідно до останньої, у присутності стійкого селф (self) конфлікт сам по собі аж ніяк не вбачається шкідливим, бо у боротьбі за звільнення від таких конфліктів народжується функціональна реабілітація та розширення компенсаторних структур. Автор відстоює твердження, що є помилковим підштовхувати селф (self) у терапії до сфер, із яких воно вже відокремилося в ранньому віці і з якими воно розірвало зв’язки, оскільки це видає нерозуміння аналізанта. Окрім того, за Когутом, аналітик може створювати перешкоди на шляху пацієнта до одужання, якщо в кожній клінічній ситуації буде намагатися застосувати універсальний шаблон із певними, на думку аналітика, обов’язковими умовами терапевтичного процесу.
ПЕРЕГЛЯД ПОТЯГУ ДО СМЕРТІ: РЕЛЯЦІЙНА ПСИХОАНАЛІТИЧНА ПЕРСПЕКТИВА
Authors: Ґайтанідіс Анастасіос
Published: August 2024

Анотація. Ця стаття переглядає суперечливу концепцію потягу до смерті Фройда з погляду сучасного реляційного психоаналізу. Потяг до смерті, уперше представлений у роботі Фройда «По той бік задоволення» (1920), являє собою вроджене прагнення людини до руйнування, хаосу та припинення життя, яке протистоїть творчій силі сексуального лібідо (Еросу). Попри свою глибоку пояснювальну силу потяг до смерті зазнав широкої критики і перегляду через свою спекулятивну метафізичну природу. Стаття доводить, що потяг до смерті може бути продуктивно переосмислений через реляційну психоаналітичну лінзу як деструктивна сила, що виникає з людських стосунків та інтерсуб'єктивності і впливає на них. Вона досліджує реляційні витоки потягу до смерті, пов'язані з невдачами емпатійного налаштування і розпізнавання в ранніх прив'язаностях, його захисні функції, що захищають від уразливості і скорботи, його включення в терапевтичну динаміку та перенесення, а також його роль у патологічних структурах особистості, таких як нарцисизм, межові стани і психози. Розглядаючи потяг до смерті як прояв спотвореної інтерсуб'єктивності та порушення систем розпізнавання, що становлять психологічне життя, ця стаття має на меті продемонструвати стійку клінічну релевантність цієї складної концепції для тем агресії, травми, скорботи та психопатології. У ній стверджується, що непряма, непрозора якість потягу до смерті гостро фіксує невикорінену негативність суб'єктивності, яка чинить опір символізації та визнанню. Наполегливі повторення і розігрування потягу до смерті оформлені як парадоксальне прагнення до міжособистісного зв'язку та турботи перед обличчям трагічного відчуження і втрати. Комплексний клінічний випадок, натхненний роботою Моріса Еппрі про трансгенераційну травму, ілюструє, як потяг до смерті несе в собі зашифровані залишки величезних колективних та історичних утрат через несвідому ідентифікацію, примус до повторення і спотворені моделі прив'язаності. Загалом стаття обґрунтовує теоретичну цінність потягу до смерті, якщо його переосмислити в рамках реляційного психоаналізу, зосередженого на інтерсуб'єктивності, взаємному визнанні та нескінченній боротьбі людини за збереження значущих міжособистісних зв'язків усупереч тяжінню екзистенціального розпаду.
Proporciones de reforzamiento inmediato y demorado sobre la tasa de respuesta en programas múltiples
Authors:   Universidad de Guadalajara, Feregrino Edith , Flores Carlos ,   Universidad de Guadalajara
Published: August 2024

En estudios sobre demora de reforzamiento se ha reportado que la tasa de respuesta es una función inversa de alargar el intervalo respuesta-reforzador. En un estudio previo, se encontró que variar la proporción de reforzamiento inmediato y reforzamiento demorado en la misma sesión moduló la disminución en la tasa de respuesta. Sin embargo, es posible que dichos resultados se deban al alargamiento del intervalo entre reforzadores (IER). El objetivo del presente estudio fue evaluar los efectos de variar la proporción de reforzamiento inmediato/demorado sobre la tasa de respuesta manteniendo constante el IER. Se usaron tres grupos de ratas a las que se les expuso a un programa múltiple de dos componentes manteniendo constante la proporción de reforzamiento inmediato/demorado para cada grupo (25/75, 50/50, 75/25, respectivamente) y en condiciones sucesivas se alargó la demora (2, 4, 8 y 16 s). Se replicó el hallazgo del gradiente de demora durante el componente demorado mientras que, en el componente inmediato la tasa de respuesta varió en función de la proporción de reforzamiento. Controlar el IER permitió descartar que el decremento en la tasa se deba a dicha variable,confirmando que los efectos de la demora de reforzamiento sobre la tasa de respuesta son modulados por la proporción de reforzamiento inmediato/demorado.
Carbohydrate quality, fecal microbiota and cardiometabolic health in older adults: a cohort study
Authors: Atzeni Alessandro , Nishi Stephanie , Babio Nancy , Belzer Clara , Konstanti Prokopis , Vioque Jesus , Corella Dolores , Castañer Olga , Vidal Josep , Moreno-Indias Isabel , Torres-Collado Laura , Asensio Eva M. , Fitó Montserrat , Gomez-Perez Ana Maria , Arias Alejandro , Ruiz-Canela Miguel , B. Hu Frank , Tinahones Francisco
J. , Salas-Salvadó Jordi
Published: August 2024

The impact of carbohydrate quality, measured by the carbohydrate quality index (CQI), on gut microbiota and health has been scarcely investigated. The aim of this study was to cross-sectionally and longitudinally explore the relationships between CQI, fecal microbiota, and cardiometabolic risk factors in an elderly Mediterranean population at high cardiovascular risk. At baseline and 1-year, CQI was assessed from food frequency questionnaires data, cardiometabolic risk factors were measured, and fecal microbiota profiled from 16S sequencing. Multivariable-adjusted linear regression models were fitted to assess the associations between tertiles of baseline CQI, fecal microbiota, and cardiometabolic risk factors at baseline, and between tertiles of 1-year change in CQI, 1-year change in fecal microbiota and cardiometabolic risk factors. Cross-sectionally, higher CQI was positively associated with Shannon alpha diversity index, and abundance of genera Faecalibacterium and Christensenellaceae R7 group, and negatively associated with the abundance of Odoribacter, and uncultured Rhodospirillales genera. Some of these genera were associated with higher glycated hemoglobin and lower body mass index. In addition, we observed a positive association between CQI, and some pathways related with the metabolism of butyrate precursors and plants-origin molecules. Longitudinally, 1-year improvement in CQI was associated with a concurrent increase in the abundance of genera Butyrivibrio. Increased abundance of this genera was associated with 1-year improvement in insulin status. These observations suggest that a better quality of carbohydrate intake is associated with improved metabolic health, and this improvement could be modulated by greater alpha diversity and abundance of specific genera linked to beneficial metabolic outcomes.
Tax Incentive-Based Economic Policy, Modern Tax Administration System, and Taxpayer Compliance of Micro, Small, and Medium Enterprises
Authors: Mapuasari Supeni Anggraeni , Wibowo Yudha Satrio , Cakranegara Pandu Adi
Published: August 2024

This study examines the effect of tax incentive-based economic policies and modern tax administration systems through e-registration, e-filing, and e-billing on Micro, Small, and Medium Enterprises (MSMEs) taxpayer compliance in Palu City during the Pandemic Period. This study analyzed primary data from questionnaires distributed to 100 MSME taxpayers in Palu City. By using the theory of planned behavior (TPB) in taxpayer compliance research, researchers can understand in more depth why taxpayers do or do not comply, as well as identify the factors that influence their decisions. Testing the research variables was carried out using the Partial Least Square (PLS) method. The results showed that Tax Incentive-Based Economic Policies have a positive effect on MSMEs' taxpayer compliance. Meanwhile, implementing modern tax administration systems, such as e-registration, e-filing, and e-billing, did not affect MSMEs' taxpayer compliance. This result sheds light on the efficiency of regulation and tax systems to encourage tax compliance. Governments and agencies need to ensure that efforts are made to increase awareness, access, and ease of use of these systems, as well as understanding and overcoming barriers that may arise in practice. These can help design more effective tax policies and educational efforts to increase taxpayer compliance.
Environmental, Social, Governance Report, and Materiality Analysis Effect on Financial and Market Performance
Authors: Indrawati Andi , Ruliana Titin , Yudhyani Eka , Nurfitriani Nurfitriani
Published: August 2024

Environmental, Social, and Governance (ESG) Reports and materiality analysis are increasingly becoming a primary focus in socially and environmentally responsible corporate practices. These two elements play an important role in building financial and market performance. This research investigates the influence of ESG Reports and materiality analysis on company financial and market performance. This research method uses secondary data from a number of companies in various industries listed in IDX during the 2017-2021 period. Based on the purposive sampling technique, the sample was 23 companies, so the data processed was 115 data. Regression analysis and other statistical techniques measure the relationship between ESG variables and a company's financial results. The research results prove that elements of social and governance ESG have a negative effect on financial performance. Materiality analysis has a positive effect on market performance. These findings provide a strong basis for companies to pay more attention to ESG, especially on the social and governance factors and materiality analysis as strategic tools in risk management and improving financial and market performance. In addition, this research also provides valuable information for investors and other stakeholders increasingly paying attention to ESG aspects in their investment decision-making. Some suggestions were made for future research on ESG reports and sustainability.
Whistleblowing System: Do seniors blow less?
Authors: Sari Rida Perwita , Surbakti Lidya Primta , Sari Rika Puspita , Nuswantara Dian Anita
Published: August 2024

To fortify itself against any harmful behavior, an organization has meticulously designed a whistleblowing policy system. Despite the availability of this channel, not all members actively engage in using it to contribute to the overall health of the organization. To address this issue effectively, organizations need to conduct in-depth analyses to identify the specific barriers within their context. Our study responds to such topical issues by observing the role of seniority in motivating organizational members to actively embrace their roles as whistle-blowers. The research specifically examines the role of maturity in influencing individuals to step forward and report wrongdoing within the organization. In doing so, we employed the moderated regressions as a methodological approach, involving 396 employees from eight East Java offices of the Directorate General of Taxation. The study's findings provide empirical support for the notion that positive attitudes toward the use of the whistleblowing system significantly increase members' intention to report instances of wrongdoing. However, the research fails to corroborate the hypothesis that age plays a significant role in influencing people’s intention to be whistle-blowers. Considering these results, the implications for organizational governance and policymaking are discussed.
Wirtualne zespoły w kontekście różnic pokoleniowych – systematyczny przegląd literatury
Authors: Koszyk Beata
Published: August 2024

W artykule dokonano syntezy wyników systematycznego przeglądu literatury z zakresu wpływu pokoleń na pracę oraz dzielących je różnic w kontekście zespołów wirtualnych. Artykuł składa się z czterech części. W pierwszej z nich dokonano przeglądu literatury. Następnie zaprezentowano procedurę badawczą (tj. cel, metodę i zakres badania), w części trzeciej przedstawiono natomiast rezultaty przeprowadzonych badań. Analizie poddano 33 artykuły polsko- i anglojęzyczne opublikowane w latach 2013–2023, wyłonione z baz Scopus, Ebsco i Web of Science. Wybrane artykuły na podstawie analizy merytorycznej podzielono na pięć obszarów: (1) wyzwania, (2) doświadczenia, perspektywy i preferencje, (3) dzielenie się wiedzą, (4) równowaga między życiem zawodowym a prywatnym oraz (5) motywacja i przywództwo. W podsumowaniu artykułu przedstawiono wnioski z przeprowadzonego badania wraz z towarzyszącymi mu ograniczeniami oraz wskazano główne nurty badawcze, które mogą stanowić przyczynek do podjęcia dalszych badań w tym obszarze.
Uproszczone sprawozdania finansowe oczami wybranych interesariuszy
Authors: Wielgórska-Leszczyńska Joanna , Zakrzewska Justyna Beata
Published: August 2024

Sprawozdania finansowe są podstawowym źródłem wiedzy o jednostce gospodarczej i efektach jej działalności oraz stanowią ważną formę komunikacji z odbiorcami. W związku z tym dane prezentowane w sprawozdaniu finansowym powinny uwzględniać potrzeby informacyjne różnych grup interesariuszy, którzy wykorzystują je do podejmowania decyzji finansowych. Ustawodawca wprowadził ograniczenie zakresu informacji ujawnianych w sprawozdaniu finansowym (uproszczenia w sprawozdawczości finansowej). Celem opracowania jest przedstawienie wpływu zakresu informacji finansowych prezentowanych w uproszczonych sprawozdaniach finansowych na postrzeganie użyteczności tych informacji przez różne grupy interesariuszy. Podjęto w związku z tym próbę znalezienia odpowiedzi na pytanie, czy informacje finansowe zawarte w uproszczonym sprawozdaniu finansowym są wystarczające do podejmowania decyzji operacyjnych i inwestycyjnych przez wybrane grupy interesariuszy (księgowych, biegłych rewidentów, analityków finansowych, przedsiębiorców). W opracowaniu wykorzystano w szczególności krytyczną analizę literatury, aktów prawnych, standardów, opracowań i publikacji, w tym metodę przeglądu systematycznego, a także zbadano wpływ uproszczeń w sprawozdawczości finansowej na użyteczność tych informacji w opinii czterech grup interesariuszy za pomocą sondażu pośredniego i bezpośredniego. Dane uzyskane w ramach badania empirycznego poddano analizie, posługując się statystyką opisową i matematyczną oraz indukcją i wnioskowaniem. W wyniku badania stwierdzono, że uproszczone sprawozdania dla jednostek mikro i innych nie są powszechnie stosowane przez przedsiębiorstwa. Jak twierdzą księgowi i biegli rewidenci, powodem tego jest przekroczenie limitów określonych w ustawie o rachunkowości, a według przedsiębiorców – brak uproszczeń w sposobie prowadzenia ksiąg rachunkowych. Zdaniem większości księgowych oraz biegłych rewidentów informacje finansowe prezentowane w uproszczonych sprawozdaniach finansowych nie są wystarczające dla kierownictwa i właścicieli jednostki oraz organów nadzorczych do oceny sytuacji majątkowej, finansowej oraz wyniku finansowego, a w szczególności płynności finansowej jednostki.
Prevalencia de diagnósticos de Enfermería en la implementación de una nueva hoja de registros de enfermería.
Authors: Portillo Cardona Armando Alberto
Published: August 2024

Objetivo: Determinar la prevalencia de diagnósticos de enfermería en la implementación de una nueva hoja de registros de enfermería. Material y métodos: Se utilizó una metodología cualitativa, documental, con un modelo de investigación de campo. Resultados: Los diagnósticos fueron riesgo de infección, dolor agudo, deterioro de la integridad cutánea, deterioro de la movilidad física y deterioro de la eliminación urinaria. Conclusión: La metodología del proceso de enfermería incluye una taxonomía de diagnósticos y otorga una mayor certeza en los cuidados brindados, dejando la puerta abierta a nuevas investigaciones que establezcan si los diagnósticos mayormente utilizados son los correctos según el tipo de pacientes, además de evaluar si se utilizan de acuerdo con la metodología correcta.
Kasvumaa
Authors: Niinivaara Eeva , Ilomäki Heini , Koskivaara Kristiina , Lappalainen Hannu-Pekka , Lehtinen Tapani , Lille Eva , Salokannel Anja
Published: August 2024

(Ei abstraktia tai tällaiseksi katsottavaa esipuhetta)
Vienalaisia lastenlauluja
Authors: Virtaranta Pertti
Published: August 2024

Alkusanat

Muistiinpanoihini on vuodesta 1951 lähtien kertynyt pari sataa Vienan naisten lapsille hyräilemää laulua. Enimmät olen kirjoittanut sanelun mukaan, pienemmän osan litteroinut ääninauhasta. Viimeksi mainittujen joukossa on myös lauluja, jotka Väinö Kaukonen äänitti yhteisellä Karjalan matkallamme kesällä 1968. "Vienalaisia lastenlauluja" sisältää tämän nimikkeen ulkopuolellekin lankeavaa ainesta, nim. 1) Rukajärven ja Tunkuan kylistä olevia lauluja, vaikka kyseiset ent. pitäjät eivät kuulukaan ns. Vienaan, 2) lasten viihdyttämiseksi luettuja loruja ja lasten omia leikkihokuja sekä 3) muutamia sellaisia lauluja, jotka eivät nimenomaisesti ole "lastenlauluja" mutta joita kyllä on lapsille lauleltu.

Kokoelmaan olen liittänyt 15 laulusävelmää. Ne on nauhoista kirjoittanut ylioppilas Kaija Pärnänen ja puhtaaksi piirtänyt musiikinopettaja Outi Tolvanen. Kiitän heitä hyvin tehdystä työstä. Karjalan sivistysseuraa kiitän siitä, että se on osallistunut painatuskustannuksiin ja siten tehnyt mahdolliseksi kokoelman ilmestymisen.

Kulosaaressa 26. toukokuuta 1973
Pertti Virtaranta
Inkeriläisiä sananlaskuja ja arvoituksia
Authors: Virtaranta Pertti
Published: August 2024

Alkusanat

Yli kolmenkymmenen vuoden aikana olen tilaisuuden tullen tehnyt muistiinpanoja - käsivaraisesti ja äänittäen - Inkerin murteista ja muustakin Inkerin perinteestä. Kertynyttä ainesta ja havaintoja sen johdosta olen julkaissut vähän: kaksi sarjaa "Näytteitä Inkerin murteista" (Virittäjä 1953 s. 381-405 ja 1955 s. 41-70), "Murretietoja Kupanitsan Greplasta" (Kalevalaseuran vuosikirja 1963 s. 200-216), näytteitä Kelton, Moloskovitsan ja Järvisaaren murteista (teoksessa "Suomen kansa muistelee" s. 335-360, 1964) ja näytteitä Laukaansuun inkeroismurteesta (kokoelmassa "Lähisukukielten lukemisto" s. 157-169, 1967). Vuosia sitten oli suunnitteilla Inkerin murrekirjakin, lähinnä ääninauhoihin tallentamani aineksen perusteella, mutta tuo ajatus on toistaiseksi jäänyt lepäämään. Murrekirjan pieneksi korvikkeeksi tulee nyt julki kokoelma inkeriläisiltä saamiani sananlaskuja ja arvoituksia - kiitos Inkeriläisten Sivistyssäätiön, joka lupasi vastata kirjasen painatuskustannuksista. Julkaisutien avauduttua aloin poimia inkeriläiskokoelmistani tämäntapaisia muistiinpanoja; mukaan otin sananlaskujen lisäksi myös muita kiinteämuotoisia ilmauksia, kuten vertauksia, sanontoja, sanomuksia, riimittelyjä, loruja, luonnehdintoja, kalendaarisia viisauksia, matkimuksia, köllejä. Inkeriläisäänitteitäni, joita on yhteensä 58 tuntia, en kuitenkaan tätä varten ryhtynyt kuuntelemaan, vaikka niissä kyllä jonkin verran olisi mukaan otettavaa ainesta.

Tämän kirjan sananlaskuja ja arvoituksia en ole sanaston enkä asian puolesta sensuroinut, vaan olen julkaissut ne juuri sellaisina kuin ne selkeällä Inkerin murteella on sanottu; näin neuvoo tekemään sananlaskujen erikoistuntija Matti Kuusi.

Muistiinpanoista poimitun aineksen vaimoni kirjoitti lipuille, ryhmitti ja aakkosti sekä kirjoitti sitten puhtaaksi. Offsetpainoa varten konekirjoitustyön suoritti Kerttu Pohja.

Kokoelma on toimitettu samaan tapaan kuin v. 1976 julkaisemani "Karjalaisia sananlaskuja ja arvoituksia" (Castrenianumin toimitteita n:o 15). Alkuluvun "Inkerin perinteen parissa" olen kirjoittanut eräiden asianharrastajien toivomuksesta.

Kiitän tämän kokoelman tukemisesta Inkeriläisten Sivistyssäätiötä, erityisesti rovasti Matti Vironmäkeä, joka on asiaa tarmokkaasti ajanut. Kiitollisena muistelen niitä Suomessa, Ruotsissa ja Neuvosto-Karjalassa tapaamiani Inkerinmaan synnynnäisiä, joiden tietoja olen tähän kirjaseen saanut.

Helsingissä 11. kesäkuuta 1978
Pertti Virtaranta
Keskusteluja Valev Uibopuun kanssa – Vestlusi Valev Uibopuuga
Authors: Virtaranta Pertti
Published: August 2024

Valev Uibopuun kanssa 1980-luvulla käymäni keskustelut, jotka tallensin ääninauhoihin, tulevat tässä kirjassa julki jokseenkin kokonaan. Kieliasua on jonkin verran korjattu kirjakielen suuntaan, mutta puhekielen luonne on kuitenkin haluttu säilyttää.
 
Keskustelut kävimme kummankin omalla äidinkielellä. Kun tein kysymykseni tai esitin kommenttini suomeksi, provosoi se joskus mainiosti suomea osaavan kumppanini aloittamaan repliikkinsä suomeksi, minkä "erehdyksen" hän pian huomasi ja jatkoi viroksi.
 
Haastattelunauhoituksissa on jonkin verran asiatoistoa. Se kuuluu tämäntapaisen vapaan keskustelun luonteeseen. Uusi asiayhteys antoi toisinaan aihetta palata jo ennen käsiteltyyn.
 
Pidin keskustelusarjaamme kulttuurihistoriallisesti niin kiintoisana, että halusin nostaa sen Viron kulttuurin ystävien luettavaksi. Mutta miten? Mistä löytyisi pätevä nauhojen litteroija ja mistä lähteistä työ ja julkaisu saataisiin rahoitetuksi? Pulma ratkesi, kun virontaitoinen itämerensuomalaisten kielten opiskelija Riho Grünthal suostui litteroimaan nauhat ja Suomalais-ugrilainen kulttuurisäätiö antoi työhön tukensa. Litteraatio valmistui 1988, ja Riho Grünthal kirjoitti sen myöhemmin puhtaaksi tietokoneella. Valev Uibopuu luki korrehtuurin ja tarkisti aikamääriä sekä nimiä. Muutaman tarpeelliseksi katsomansa lisäyksen hän myös samalla teki. – Haastattelunauhat olen antanut Suomen kielen nauhoitearkistoon (nauhat 13825-6, 13929-32, 14141–2 ja 15317, yhteensä n. 10 tuntia).
 
Tämän hieman erikoisen kirjan nyt valmistuessa osoitan kiitoksen sanat ennen muita tietenkin Valev Uibopuulle keskustelukumppanuudesta ja kaikesta avusta, jota hän on kirjan teossa auliisti antanut. Kaunis kiitos kuuluu myös Riho Grünthalille; hän on hyvin hoitanut työlään tehtävänsä. Siitä, että hanke toteutui, minun on kiittäminen Suomalais-ugrilaista kulttuurisäätiötä, sen johtokuntaa, joka katsoi litteroinnin tukemisen arvoiseksi. Säätiö osallistui myös kirjan painatuskuluihin.
 
Enimmät kirjan kuvista ovat Valev Uibopuun kotiarkistosta.
 
Helsingissä 24. helmikuuta 1991
Pertti Virtaranta
Psychological Well-Being Pada Mahasiswa Rantau: Adakah Pengaruh Dari Dukungan Sosial dan Penyesuaian Diri?
Authors: Eviliani Afrisa , Nurhayaty Any , Syah Tansri Adzlan
Published: August 2024

Psychological well-being is a condition where individuals feel their life is meaningful when they are able to demonstrate and gain personal self-acceptance, control over the environment, have convincing interpersonal relationships, personal growth and autonomy, several factors that can influence psychological well-being. Welfare can lead to social service support provided by someone with good adjustment. The purpose of this research is to determine the effect of social support and adjustment on the psychological well-being of overseas students. The instruments used in this research were the Ryff's Scale of Psychological Well-Being (RSPWB) developed by Ryff, the Social Provision Scale by Cutrona, C.E and Russel as a social support scale, and a self-adjustment scale compiled based on six aspects based on opinions from Schneiders as many as 30 items. Data analysis techniques are used to test the hypothesis and correlation with the help of SPSS version 25 data processing. The results of the research suddenly show a correlation that leads to social support and self-adjustment which is associated with the psychological well-being of overseas students,recorded with a correlation coefficient of 0.692 and a significance score of 0.000 (p > 0.05). Thus the hypothesis proposed in this research is accepted.
PERBEDAAN KEMAMPUAN LITERASI NUMERASI MELALUI MODEL PEMBELAJARAN PROBLEM BASED LEARNING (PBL) DAN PROJECT BASED LEARNING (PjBL) PADA POKOK BAHASAN PROGRAM LINEAR
Authors: Khairi Siregar Alfi , Maysarah Siti
Published: August 2024

Penelitian ini bertujuan untuk melihat perbedaan kemampuan literasi numerasi siswa yang diajar dengan model pembelajaran Problem Based Learning pada kelas XI MIA 2 dan Project Based Learning pada kelas XI MIA 2 pada materi Program Linear. Penelitian ini menggunakan metode eksperimen dengan rancangan The post-test two experimental group design dengan populasi 5 kelas XI MIA berjumlah 179 siswa dan sampel 2 kelas yaitu XI MIA 1 berjumlah 36 siswa dan XI MIA 2 berjumlah 35 siswa dengan instrumen penelitian berupa 2 soal essay mencakup indikator kemampuan literasi numerasi. Didapatkan hasil penelitian tidak ada perbedaan yang signifikan antara kelas XI MIA 1 dan XI MIA 2 terhadap kemampuan literasi numerasi siswa pada materi Program Linear
EKSPLORASI ETNOMATEMATIKA PADA MOTIF TENUN SONGKET MELAYU BUDAYA BATU BARA
Authors: Azizah Isnaini , Ananda Rusydi
Published: August 2024

Tujuan dari penelitian ini adalah untuk mengetahui konsep-konsep matematika yang terdapat pada Motif Tenun Songket Melayu Budaya Batu Bara. Metode penelitan yang digunakan dalam penelitan ini yaitu menggunakan kualitatif deskriptif dengan pendekatan etnografi. Pendekatan etnografi adalah pendekatan empiris dan teoritis yang bertujuan untuk mendapatkan gambaran dan analisis budaya melalui penelitian lapangan. Hasil penelitian ini ditemukan konsep matematika bentuk geometri yang secara khusus digunakan dalam Motif Tenun Songket Melayu, terkhusus pada konsep bangun datar yaitu, segitiga, belah ketupat, elips dan lingkaran. Konsep Barisan Aritmatika juga terdapat pada Motif Tenun Songket Melayu ini yaitu terdapat motif yang memiliki bentuk yang sama namun ditemukan berulang. Kesimpulan nya etnomatika sangat sederhana dan dapat di lihat secara nyata pada motif-motif Tenun Songket Melayu Budaya Batubara.
Integrasi Microsoft Office 365 dengan Kahoot pada Pembelajaran Matematika
Authors: Irmayanti Irmayanti , Mirna Mirna
Published: August 2024

Era digital ini menuntut guru harus inovatif dan kreatif dalam pembelajaran. Salah satu aplikasi yang digunakan guru SMPN 12 Sinjai dalam pembelajaran adalah office 365. Selain itu, guru matematika mengintegrasikan office 365 dengan aplikasi kahoot. Penelitian ini bertujuan untuk mendeskripsikan integrasi pemanfaatan aplikasi microsoft office 365 dengan kahoot pada pembelajaran matematika materi bangun ruang. Jenis penelitian yang digunakan dalam penelitian ini adalah deskripsi dengan pendekatan kualitatif. Subjek penelitian terdiri dari guru dan empat orang siswa SMPN 12 Sinjai kelas VIII. Pengumpulan data yang digunakan adalah observasi, wawancara dan dokumentasi. Instrumen yang digunakan adalah lembar observasi, lembar wawancara dan dokumentasi. Lembar observasi digunakan untuk mengamati proses pembelajaran yang dilakukan oleh guru, lembar wawancara digunakan untuk mengetahui secara mendalam tentang pemanfaatan microsoft office 365 yang diintegrasikan dengan kahoot sedangkan dokumentasi digunakan untuk mendokumentasikan proses pembelajaran dan lembar kerja siswa dalam pembelajaran matematika. Analisis data pada penelitian ini adalah proses reduksi data, penyajian data dan penerikan kesimpulan. Hasil dari penelitian ini adalah integrasi fitur microsoft office 365 form dengan platform kahoot dapat memberikan manfaat tambahan dalam pengalaman pembelajaran interaktif di kelas yaitu meningkatkan keterlibatan siswa, memperkaya pengalaman pembelajaran, pengukuran kinerja dan pemahaman, efisiensi administrasi, dan peningkatan kolaborasi.
Editorial: Ebony & Ivory - History, Contexts and Practices Related to Piano
Authors: Benetti Alfonso
Published: August 2024

Not applicable.
Immunotherapy with biodegradable nanoparticles encapsulating the oligosaccharide galactose-alpha-1,3-galactose enhance immune tolerance against alpha-gal sensitization in a murine model of alpha-gal syndrome
Authors: Saunders Michael N. , Rival Claudia M. , Mandal Mahua , Cramton Kayla , Rad Laila M. , Janczak Katarzyna W. , Williams Laura A. , Angadi Amogh R. , O’Konek Jessica J. , Shea Lonnie D. , Erickson Loren D.
Published: August 2024

IgE antibodies against the mammalian oligosaccharide allergen galactose-α-1,3-galactose (αGal) can result in a severe allergic disease known as alpha-gal syndrome (AGS). This syndrome, acquired by tick bites that cause αGal sensitization, leads to allergic reactions after ingestion of non-primate mammalian meat and mammalian-derived products that contain αGal. Allergen-specific immunotherapies for this tickborne allergic syndrome are understudied, as are the immune mechanisms of allergic desensitization that induce clinical tolerance to αGal. Here, we reveal that prophylactic administration of αGal glycoprotein-containing nanoparticles to mice prior to tick protein-induced αGal IgE sensitization blunts the production of Th2 cytokines IL-4, IL-5, and IL-13 in an αGal-dependent manner. Furthermore, these effects correlated with suppressed production of αGal-specific IgE and hypersensitivity reactions, as measured by reduced basophil activation and histamine release and the systemic release of mast cell protease-1 (MCPT-1). Therapeutic administration of two doses of αGal-containing nanoparticles to mice sensitized to αGal had partial efficacy by reducing the Th2 cytokine production, αGal-specific IgE production, and MCPT-1 release without reducing basophil activation or histamine release. These data identify nanoparticles carrying encapsulated αGal glycoprotein as a potential strategy for augmenting αGal-specific immune tolerance and reveal diverse mechanisms by which αGal nanoparticles modify immune responses for established αGal-specific IgE-mediated allergic reactions.
RIPS (rapid intuitive pathogen surveillance): a tool for surveillance of genome sequence data from foodborne bacterial pathogens
Authors: Muruvanda Tim , Rand Hugh , Pettengill James , Pightling Arthur
Published: August 2024

Monitoring data submitted to the National Center for Biotechnology Information’s Pathogen Detection whole-genome sequence database, which includes the foodborne bacterial pathogens Listeria monocytogenes, Salmonella enterica, and Escherichia coli, has proven effective for detecting emerging outbreaks. As part of the submission process, new sequence data are typed using a whole-genome multi-locus sequence typing scheme and clustered with sequences already in the database. Publicly available text files contain the results of these analyses. However, contextualizing and interpreting this information is complex. We present the Rapid Intuitive Pathogen Surveillance (RIPS) tool, which shows the results of the NCBI Rapid Reports, along with appropriate metadata, in a graphical, interactive dashboard. RIPS makes the information in the Rapid Reports useful for real-time surveillance of genome sequence databases.
In silico studies of benzothiazole derivatives as potential inhibitors of Anopheles funestus and Anopheles gambiae trehalase
Authors: Ogunnupebi Temitope A. , Oduselu Gbolahan O. , Elebiju Oluwadunni F. , Ajani Olayinka O. , Adebiyi Ezekiel
Published: August 2024

Introduction

In malaria management, insecticides play a crucial role in targeting disease vectors. Benzothiazole derivatives have also been reported to possess insecticidal properties, among several other properties they exhibit. The female Anopheles mosquito is responsible for transmitting the malaria parasite when infected. Anopheles gambiae (Ag) and Anopheles funestus (Af) are two of the most notable Anopheles species known to spread malaria in Nigeria. Trehalase is an enzyme that breaks down trehalose. Recent research has proposed it as a viable target for inhibition since it aids in flight and stress adaptation.

Methods

This study aimed to investigate benzothiazole derivatives as potential inhibitors of trehalase of Anopheles funestus (AfTre) and Anopheles gambiae (AgTre) using toxicity profiling, molecular docking, and dynamic simulation for future insecticidal intervention. A total of 4,214 benzothiazole-based compounds were obtained from the PubChem database and subjected to screening against the 3D modelled structure of AfTre and AgTre. Compounds with some toxicity levels were optimised, and the obtained lead compounds were further investigated through molecular docking studies. Furthermore, the best hit was subjected to parameters such as RMSD, RMSF, SASA, Rg, and hydrogen bond to confirm its stability when in a complex with AfTre, and these parameters were compared to that of validamycin A (control ligand).

Results and discussion

The post-screening analysis showed binding affinities of −8.7 and −8.2 kcal/mol (compound 1), −8.2 and −7.4 kcal/mol (compound 2), compared to −6.3 and −5.1 kcal/mol (Validamycin A, a known inhibitor) against AfTre and AgTre, respectively. The molecular dynamics simulation showed that compound 1 (the best hit) had good stability when in complex with AfTre. These findings suggest that these best hits can serve as potential inhibitors for the development of novel insecticides in the control of malaria vectors.
Case Report: Electroanatomic mapping as an early diagnostic tool in arrhythmogenic cardiomyopathy
Authors: de Melo Jose F. , Shabtaie Samuel A. , van Zyl Martin , Collins Jeremy D. , Siontis Konstantinos C.
Published: August 2024

Background

Abnormal substrate on invasive electroanatomic mapping (EAM) correlates with areas of myocardial thinning and fibrofatty replacement in Arrhythmogenic Cardiomyopathy (ACM). However, EAM parameters are absent from all sets of diagnostic criteria for ACM.

Case summary

A 41-year-old female with no significant family history was referred for evaluation of frequent premature ventricular complexes (PVCs). Twelve-lead ECG showed diffuse low-voltage QRS complexes. Holter monitor showed 28% burden of PVCs with various morphologies consistent with right ventricular (RV) inflow and outflow tract exits. Transthoracic echocardiogram revealed normal biventricular function and dimension. Cardiac magnetic resonance revealed a mildly increased indexed RV end-diastolic volume with normal RV systolic function and no dyssynchrony, akinesia, dyskinesia, or late gadolinium enhancement. Electrophysiologic study demonstrated 2 predominant PVC morphologies that were targeted with ablation, in addition to extensive abnormality with low-voltage and fractionated electrograms in the peri-tricuspid and right ventricular outflow tract free wall regions with septal sparing, suggestive of RV cardiomyopathy. Subsequent genetic testing revealed two pathogenic variants in the desmoplakin and plakophilin-2 genes, confirming the diagnosis of ACM.

Conclusion

Advanced RV electropathy can precede RV structural changes in ACM. Invasive evaluation of the electroanatomic substrate should be considered in select cases even when imaging findings are not diagnostic. Future iterations of ACM guidelines may need to consider EAM substrate as one of the diagnostic criteria. A high index of diagnostic suspicion for ACM should be maintained in patients with multifocal RV ectopy.
Slope reliability assessment using an innovative critical failure path approach
Authors: Tang Xiyang , Chen Chen , Shan Dan , Zhang Pengtao , Xue Jianghan
Published: August 2024

Slope instability, driven by factors such as rainfall, seismic activity, and human influence, presents a pervasive hazard worldwide. Timely assessment of slope stability and accurate identification of its most critical slip surface are important for slope safety early warning and management. Currently, for the slope reliability analysis by the strength reduction method (SRM), the critical failure path is approximately determined through visualization techniques, which is not sufficiently precise. Therefore, this study proposes a critical failure search method based on SRM for slope reliability analysis, aiming to accurately identify the critical slip surface. The critical failure path is considered as the path with the maximum plastic dissipative energy density (PDED) and is searched in the constructed weighted graph based on the dissipated energy of the slope. This proposed method is further applied with an engineering slope to find the critical failure path and assess its reliability during and after construction. The searched critical failure path lies within the approximate range obtained through conventional visualization methods. Finally, a reliability prediction model consisting of time, rainfall, and deformation component is further constructed, which allows rapid estimation of the slope reliability through available monitor data. The results of reliability analysis indicate that construction disturbances have a significant impact on slope stability, along with other factors such as rainfall and creep.
PhD-supervisors experiences during and after the COVID-19 pandemic: a case study
Authors: Krumsvik Rune J. , Røkenes Fredrik Mørk , Skaar Øystein O. , Jones Lise , Solstad Stein H. , Salhus Øystein , Høydal Kjetil L.
Published: August 2024

Introduction

The COVID-19 pandemic has significantly impacted the education sector, and this case study examined nearly three hundred PhD supervisors in Norway. The study was driven by the urgent need to better understand the professional, social, and existential conditions faced by doctoral supervisors during extended societal shutdowns. This explorative case study builds on a former study among PhD candidates and investigates the experiences of doctoral supervisors when remote work, digital teaching, and digital supervision suddenly replaced physical presence in the workplace, largely between March 12, 2020, and autumn 2022, due to the COVID-19 pandemic.

Methods

A mixed-methods research approach, incorporating formative dialog research and case study design, was employed to bridge the conceptual and contextual understanding of this phenomenon. The primary data sources were a survey (N = 298, 53.7% women, 46.3% men, response rate 80.54%) and semi-structured interviews (with nine PhD supervisors). Supplementary data collection was based on formative dialog research. It included field dialog (four PhD supervision seminars), open survey responses (n = 1,438), one focus group (n = 5), an additional survey (n = 85), and document analysis of PhD policy documents and doctoral supervision seminar evaluations (n = 7). The survey data, interview data, focus group data, and supplementary data focus also retrospectively on the first year of the pandemic and were collected from August 2022 until October 2023.

Results

The findings from the explorative case study revealed that the PhD supervisors faced numerous challenges during the pandemic, both professionally and personally. For PhD supervisors who extensively worked from home over a long period, the situation created new conditions that affected their job performance. These altered conditions hindered their research capacity, their ability to follow up with their PhD candidates, and their capacity to fulfill other job responsibilities. Although the PhD supervisors received some support during the pandemic, it seems that the incremental measures provided were insufficient.

Discussion

The case study results indicate that it is more important than ever to understand the gap between the formulation, transformation, and realization arenas when distinguishing between incremental, semi-structural changes and fundamental changes in PhD regulations and guidelines brought on by societal crises. This highlights the need for better crisis preparedness at the doctoral level in the years to come.
Cadmium activation of wild-type and constitutively active estrogen receptor alpha
Authors: Psaltis John B. , Wang Qiaochu , Yan Gai , Gahtani Reem , Huang Nanxi , Haddad Bassem R. , Martin Mary Beth
Published: August 2024

The estrogen receptor alpha (ERα) plays a central role in the etiology, progression, and treatment of breast cancers. Constitutively activating somatic mutations Y537S and D538G, in the ligand binding domain (LBD) of ESR1, are associated with acquired resistance to endocrine therapies. We have previously shown that the metalloestrogen calcium activates ERα through an interaction with the LBD of the receptor. This study shows that cadmium activates ERα through a mechanism similar to calcium and contributes to, and further increases, the constitutive activity of the ERα mutants Y537S and D538G. Mutational analysis identified C381, N532A, H516A/N519A/E523A, and E542/D545A on the solvent accessible surface of the LBD as possible calcium/metal interaction sites. In contrast to estradiol, which did not increase the activity of the Y537S and D538G mutants, cadmium increased the activity of the constitutive mutants. Mutation of the calcium/metal interaction sites in Y537S and D538G mutants resulted in a significant decrease in constitutive activity and cadmium induced activity. Mutation of calcium/metal interaction sites in wtERα diminished binding of the receptor to the enhancer of estrogen responsive genes and the binding of nuclear receptor coactivator 1 and RNA polymerase II. In contrast to wtERα, mutation of the calcium/metal interaction sites in the Y537S and D538G mutants did not diminish binding to DNA but prevented a stable interaction with the coactivator and polymerase. Growth assays further revealed that calcium channel blockers and chelators significantly decreased the growth of MCF7 cells expressing these constitutively active mutants. Taken together, the results suggest that exposure to cadmium plays a role in the etiology, progression, and response to treatment of breast cancer due, in part, to its ability to activate ERα.
Adjunctive benefits of low-frequency transcutaneous electrical nerve stimulation for obesity frequent chronic conditions: a systematic review
Authors: Yu An , Li Xiang , Zhang Wei , Zhang Yazhou , Chen Xi , Wang Liuyan , Xie Mei , Yang Lei
Published: August 2024

Background

Obesity is widely recognized for its role in predisposing individuals to a spectrum of chronic health conditions. Emerging preliminary evidence points to the potential benefits of low-frequency transcutaneous electrical nerve stimulation (Lo-TENS) in enhancing various health outcomes among those with obesity and associated disorders.

Objective

This systematic review was designed to assess the effectiveness of Lo-TENS for managing obesity and its related chronic diseases.

Methods

For this systematic review, we included randomized controlled trials that evaluated the impact of Lo-TENS on individuals with obesity and its associated chronic diseases.

Results

Eight trials encompassing 671 participants and spanning three unique populations: essential hypertension (EH), type 2 diabetes mellitus (T2DM), and obesity were deemed eligible for inclusion in this review. Compared to baseline measurements, Lo-TENS demonstrated a tendency to positively affect blood pressure in individuals with EH and metabolic parameters in those with T2DM. Nonetheless, the efficacy of Lo-TENS in treating obesity is not yet clear when contrasted with a no-intervention control group. When compared with other intervention modalities, three of the trials reported less favorable results.

Conclusions

Although Lo-TENS did not consistently surpass other treatments or yield substantial improvements, it generally provided greater benefits than the majority of placebo controls. This suggests that Lo-TENS could potentially serve as a beneficial adjunctive therapy in the management of obesity and its associated conditions. However, given the limited number of trials assessed, the elevated risk of bias within these studies, and the scarce evidence currently available, it is too early to reach definitive conclusions. Caution should be exercised when interpreting the current findings. There is an imperative for further high-quality research to thoroughly investigate and substantiate the efficacy of Lo-TENS in relation to obesity and its related disorders.
A loss of function mutation in SOCS2 results in increased inflammatory response of macrophages to TLR ligands and Staphylococcus aureus
Authors: Guzylack-Piriou Laurence , Gausseres Blandine , Tasca Christian , Hassel Chervin , Tabouret Guillaume , Foucras Gilles
Published: August 2024

Introduction

The role of suppressor of cytokine signaling (SOCS)2 in anti-infective bacterial immunity has been poorly investigated compared to other members of the SOCS family.

Methods

We characterized the previously identified loss of function R96C point mutation of SOCS2 using a genome-edited mouse model that resumes the phenotype of Socs2 knockout mice. The response of macrophages to TLR-ligands and Staphylococcus aureus was examined.

Results and discussion

Conversely to previously published data using human monocyte-derived macrophages, the stimulation of bone-marrow-derived macrophages with various TLR ligands did not show any difference according to the SOCS2 variant. Upregulation of IL-6 and TNF-α pro-inflammatory cytokines production was only seen when the SOCS2 expression was promoted by the culture of macrophages in the presence of GM-CSF. Furthermore, we showed that the SOCS2 point mutation is associated with heightened STAT5 phosphorylation in a short time frame upon GM-CSF incubation. In mice, recruitment of neutrophil and F4/80int Ly6C+ inflammatory macrophage, as well as IFN-γ and IL-10 concentrations, are significantly increased upon S. aureus peritoneal infection. Altogether, these data support the idea that by lowering the pro-inflammatory environment, SOCS2 favors better control of bacterial burden during a systemic infection caused by S. aureus.