bluuebunny/crossref_metadata_2025 huggingface dataset:
Early diagnosis of coxitis in ankylosing spondylitis
Authors: Erdes Sh. F. , Agafonova E. M. , Dubinina T. V. , Demina A. B. , Smirnov A. V.
Published: August 2023

Coxitis is one of the characteristic clinical manifestations of ankylosing spondylitis (AS). Hip joint (HJ) involvement in AS is considered an un-favorable prognostic factor. Early detection of coxitis is of great importance, since with the timely initiation of adequate treatment, the risk of developing irreversible changes in HJ can be reduced.

The lecture discusses the issues of clinical and instrumental diagnosis of coxitis in AS and presents an algorithm for its early detection developed by the authors.
A clinical case of development of Waterhouse-Friderichsen syndrome after SARS-CoV-2 infection in a patient with rheumatoid arthritis and secondary adrenal AA-amyloidosis
Authors: Alpidovskaya O. V.
Published: August 2023

We present a clinical observation of a patient whose cause of death was a new coronavirus infection COVID-19 complicated by bilateral viral interstitial pneumonia and adult acute respiratory distress syndrome. The presence of background diseases-rheumatoid arthritis and secondary AA-adrenal amyloidosis-worsened the prognosis. Waterhouse-Friderichsen syndrome with hemorrhage and foci of necrosis in the adrenal cortex developed against a background of SARS-CoV-2 infection. The unique feature of this case is the long-term favorable course of the disease and its rapid progression after infection with SARS-CoV-2. The associated syndrome of disseminated intravascular coagulation further aggravated the patient's condition.
Cardiovascular safety of xanthine oxidase inhibitors: an optimistic and unfinished story
Authors: Eliseev M. S. , Zhelyabina O. V.
Published: August 2023

Gout is associated with a high risk of cardiovascular diseases and associated mortality. Possible causes of the disease include persistent uncontrolled hyperuricemia, a chronic microcrystalline inflammation that develops in the vascular wall and even in atherosclerotic plaques. These processes, which contribute to oxidative stress and the formation of peroxidation products, may be a target for xanthine oxidase inhibitors — allopurinol and febuxostat. Their rational use, aimed at complete dissolution of urate crystal deposits in gout patients, results in improvement of endothelial function, lowering of blood pressure, and possibly reduction of all-cause and cardiovascular mortality. The effects on cardiovascular risk and safety of these drugs are believed to be comparable, greatly expanding the options for gout therapy.
Genesa Marmer Daerah Mata Wawatu dan Sanggula, Kecamatan Moramo Utara, Konawe Selatan Berdasarkan Karakteristik Tekstur, Struktur, dan Asosiasi Batuannya
Authors: Azzaman Muhammad Arba , Titisari Anastasia Dewi
Published: August 2023

Salah satu daerah penghasil marmer di Provinsi Sulawesi Tenggara adalah Desa Mata Wawatu dan Sanggula, Kecamatan Moramo Utara, Kabupaten Konawe Selatan. Penelitian ini dilakukan untuk menginterpretasi genesa marmer yang meliputi tipe dan fasies metarmorfisme berdasarkan karakteristik tekstur, struktur, dan asosiasi batuannya. Ketiga parameter tersebut diketahui dengan melakukan observasi geologi, deskripsi singkapan dan sampel batuan, dan analisis petrografi. Hasilnya menunjukkan bahwa lokasi penelitian tersusun oleh tiga satuan batuan, yaitu Satuan Marmer, Satuan Filit, dan Satuan Konglomerat dengan struktur geologi berupa kekar, sesar geser sinistral, dan sesar geser sinistral diperkirakan yang terbentuk oleh gaya utama berarah relatif utara timur laut – selatan barat daya. Filit memperlihatkan stuktur foliasi tipe filitik dan tekstur hipidioblastik, kristaloblastik, dan lepidoblastik serta tekstur khusus berupa augen dan mortar. Mineralogi filit terdiri dari kuarsa, muskovit, grafit, klorit, dan mineral opak. Sementara itu, marmer di daerah penelitian menunjukkan struktur non foliasi. Namun, di beberapa tempat marmer menunjukkan retakan–retakan intensif dan struktur syn-genetic berupa perlapisan yang diduga merupakan struktur batuan asalnya, dengan variasi tekstur berupa hipidioblastik, xenoblastik, kristaloblastik, nematoblastik, granoblastik, granuloblastik serta tekstur khusus yang terdiri tekstur augen, saccaroidal, dan mortar.  Komposisi marmer tersusun oleh mineral kalsit, dolomit, kuarsa, muskovit, klorit dan mineral opak. Karakteristik tekstur dan struktur pada marmer serta asosiasi batuan termasuk himpunan mineralnya mengindikasikan bahwa marmer di lokasi penelitian terbentuk oleh proses metamorfisme regional, bersama dengan filit, pada fasies sekis hijau.
Stress in plant and their benefits for the secondary compound accumulation: a review
Authors: Tran Thanh Thang , Hai Van Phan
Published: August 2023

In recent years, crops have often experienced an increasing number of abiotic and biotic stresses, which significantly impair their growth and output due to global warming and accompanying climatic irregularities. Many studies have been carried out to improve plants' stress tolerance, including using fertilizers, microbial interactions, plant growth regulator application, and other methods. However, stress's role in improving a plant's ability to create a variety of secondary compounds such as phenolic acid, flavonoids, and anthocyanins, some of which have been linked to antioxidant activity and positive impacts on health, has yet to be well investigated. This review aims to summarize the potential for stress concerning the use of secondary compound content in plants.
Preparation and performance of homogenous braids-reinforced poly (p-phenylene terephthamide) hollow fiber membranes
Authors: Wang Chun , Yan Dinghe , Song Shubin , Yan Jingjing , Xue Haolong , Xiao Changfa
Published: August 2023

A novel homogenous braid-reinforced (HBR) poly (p-phenylene terephthamide) (PPTA) hollow fiber membrane was prepared in this study. The effects of PPTA concentration on the morphologies and properties of the membranes were further investigated. The results showed that when the PPTA concentration was 2.0 wt%, the cross-sectional morphology of satisfactory interfacial bonding was achieved and the permeation was still maintained at about 200 (L·m−2·h−1) after ultrasonic vibration. In addition, the tensile force exceeded 600 N, which indicated that the homogeneous effect effectively improved the poor mechanical properties and interfacial bonding. In addition, the HBR PPTA hollow fiber membranes were applied to simulate the membrane bioreactor system to explore the control factors of membrane fouling. The results demonstrated that the average removal of total phosphorus and NH4
+–N was above 49% and 96%, respectively; meanwhile, the operating time was up to 120 days. Furthermore, it was easier to nearly remove the pollutants by chemical cleaning.
The intersection of technology and mental health: enhancing access and care
Authors: Altaf Dar Mohd , Maqbool Mudasir , Ara Irfat , Zehravi Mehrukh
Published: August 2023

In recent times, technology has increasingly become a central force in shaping the landscape of mental health care. The integration of various technological advancements, such as teletherapy, virtual care platforms, mental health apps, and wearable devices, holds great promise in improving access to mental health services and enhancing overall care. Technology’s impact on mental health care is multi-faceted. Teletherapy and virtual care have brought about a revolution in service delivery, eliminating geographical barriers and offering individuals convenient and flexible access to therapy. Mobile mental health apps empower users to monitor their emotional well-being, practice mindfulness, and access self-help resources on the move. Furthermore, wearable devices equipped with biometric data can provide valuable insights into stress levels and sleep patterns, potentially serving as valuable indicators of mental health status. However, integrating technology into mental health care comes with several challenges and ethical considerations. Bridging the digital divide is a concern, as not everyone has equal access to technology or the necessary digital literacy. Ensuring privacy and data security is crucial to safeguard sensitive client information. The rapid proliferation of mental health apps calls for careful assessment and regulation to promote evidence-based practices and ensure the delivery of quality interventions. Looking ahead, it is vital to consider future implications and adopt relevant recommendations to fully harness technology’s potential in mental health care. Continuous research is essential to evaluate the efficacy and safety of digital interventions, fostering collaboration between researchers, mental health professionals, and technology developers. Proper training on ethical technology utilization is necessary for mental health practitioners to maintain therapeutic boundaries while leveraging technological advancements responsibly.
Prehabilitation in elective surgical interventions – what must the general and abdominal surgeon know
Authors: Meißner Carl , Meyer Frank , Ridwelski Karsten
Published: August 2023

Objectives

For years, many efforts have been invested to prepare patients, in particular, those with reduced physical and psychic status, much better to provide and finally achieve better outocme if there is time available to provide several beneficial measures.

Methods

Therefore, the objective was to illustrate the concept and various single elements of a complex prehabilitation concept based on (i) selective references from the medical literature and (ii) own clinical experiences from clinical practice in general and abdominal surgery.

Results

Prehabiliation can be considered the solution of the efforts to improve preoperative status for patients in a disadvantageous status for almost all types of surgery and all other operative and/or interventional procedures. It is the targeted process to improve individual functionality and organ function before a planned (elective) surgical intervention; P. comprises basically nutritional, physical and psychological measures; P. focusses especially onto the elderly, frail and malnourished patients before a planned surgical intervention; the overall aim is to significantly improve final outcome characterized by shorter length of stay, lower complication rate and mortality as well as cost efficiency; P. is especially important in cancer surgery, in which the beneficial effects can be particularly implemented; P. programs and/or “Standard Operating Protocols“ (SOP) may help to establish and materialize its single aspects and enhanced recovery after surgery (ERAS). There is still further potential to reliably establish and to utilize the options of prehabilitation measures as listed above.

Conclusions

Prehabiliation is an indispensable aspect in today’s preparation for elective surgery, which needs to become obligatory part of the preparation measures to planned surgical interventions, which can further contribute to a better final outcome and ERAS as well as, in addtion, needs to be further developed and accomplished.
Crystal structure of poly[diaqua-(bis(μ2-1,4-bis(imidazol-1-ylmethyl)benzene)-κ2
N,N′] cobalt(II)-tetraqua-bis(1,4-bis(imidazol-1-ylmethyl)benzene)-κ1N)-cobalt(II) di(2,5-thiophenedicarboxylate) dihydrate, C68H76Co2N16O16S2
Authors: Chen Jie , Liu Yang
Published: August 2023

C68H76Co2N16O16S2, monoclinic, P21/c (no. 14), a = 14.097(10) Å, b = 19.208(15) Å, c = 18.998(10) Å, β = 130.71(3)°, V = 3899(5) Å3, Z = 4, R
gt(F) = 0.0361, wR
ref(F
2) = 0.0850, T = 296.15 K.
Chemical data evaluation: general considerations and approaches for IUPAC projects and the chemistry community (IUPAC Technical Report)
Authors: Shaw David G. , Bruno Ian , Chalk Stuart , Hefter Glenn , Hibbert David Brynn , Hutchinson Robin A. , Magalhães M. Clara F. , Magee Joseph , McEwen Leah R. , Rumble John , Russell Gregory T. , Waghorne Earle , Walczyk Thomas , Wallington Timothy J.
Published: August 2023

The International Union of Pure and Applied Chemistry has a long tradition of supporting the compilation of chemical data and their evaluation through direct projects, nomenclature and terminology work, and partnerships with international scientific bodies, government agencies, and other organizations. The IUPAC Interdivisional Subcommittee on Critical Evaluation of Data has been established to provide guidance on issues related to the evaluation of chemical data. In this first report, we define the general principles of the evaluation of scientific data and describe best practices and approaches to data evaluation in chemistry.
Metallographic preparation of a composite of meteorite iron, steel, pure iron, and nickel manufactured by the Damascus technique
Authors: Strobl S. , Scheiblechner W. , Haubner R.
Published: August 2023

A composite material was subjected to metallographic examination. It was manufactured by forging together different ferrous materials and nickel. This technique ranks among the Damascus techniques and is also used to manufacture so-called “krises”. A kris is a traditional dagger from Southeast Asia, particularly from Indonesia and Malaysia, manufactured by processing different iron and nickel alloys or meteorite iron containing nickel. As is typical for Damascus materials, widely varied patterns are obtained on the blades which may have different shapes.

To manufacture a kris blade, sheets made of pure iron, C10 steel, meteorite iron, and nickel were forge-welded in preliminary tests. Samples were taken and subjected to metallographic examinations. Different layers can be recognized after polishing. Etchants typically used for steels (Nital, Klemm) cannot be used to reveal the nickel microstructure. The nickel grain boundaries can be revealed by ion etching. To improve the different ferrous material microstructures’ contrast, an additional heat tinting process was performed.

The metallographic examination reveals that forge welding created a homogeneous joint between the individual layers.
Effect of alkaline treatment time of fibers and microcrystalline cellulose addition on mechanical properties of unsaturated polyester composites reinforced by cantala fibers
Authors: Raharjo Wahyu Purwo , Ariawan Dody , Diharjo Kuncoro , Raharjo Wijang Wisnu , Kusharjanta Bambang
Published: August 2023

The aim of this study is to investigate the effect of alkaline treatment and addition of microcrystalline cellulose (MCC) on the density, tensile strength, elastic modulus, impact strength, and Poisson’s ratio of unsaturated polyester resin composites reinforced by cantala fibers (UPR-CFs). The fibers were immersed in alkaline solution of 6% NaOH for 0, 3, 6, 9, and 12 h. The composite had cantala fibers (CFs) and MCC volume fraction (v
f) of 30 and 5%, respectively. The results showed that the alkaline treatment for 6 h resulted in the highest density, tensile strength, and elastic modulus of the composites, while the highest Poisson’s ratio was achieved in UPR-untreated CF composites. The addition of MCC filler also increased the density, tensile strength, and elastic modulus of the composite significantly. Both alkaline treatment and MCC addition did not significantly affect the impact strength. With the increase in the strength and modulus of elasticity, composites can be applied more widely to structures that bear higher loads.
Egy kitalált hagyomány: a Tenkes kapitánya
Authors: Erdős Zoltán
Published: August 2023

A Rákóczi-szabadságharc legfontosabb eseményei elkerülték Baranya vármegyét, így nem meglepő, hogy ez a térség Rákóczi-hagyományokkal is csak nagyon szórványosan és érintőlegesen rendelkezik. A nemzeti emlékezetnek azonban olyannyira szerves részét képezi a korszak, hogy szinte magától értetődik az irodalmi és filmes megformálása – Baranya viszonylatában is.
Örsi Ferenc gyakorlatilag támpontok nélkül írta meg A Tenkes kapitánya című forgatókönyvet, majd az ifjúsági regényt, ami – jóformán már elkészülte előtt – óriási népszerűségre tett szert, később pedig bekerült a populáris kultúrába, és részévé vált a siklósiak történeti tudatának.
A dolgozat elején azt a kérdést vizsgálom, hogy a szerző milyen forrásokra hagyatkozott, és hogyan használta, hogyan gondolta tovább azokat. Ezután a „kitalált hagyomány” utóéletét, szervesülésének folyamatát mutatom be, arra fókuszálva, hogy A Tenkes kapitánya hogyan vált identitásformáló tényezővé, legújabban pedig a város- és térségmarketing részévé.
Ezen szempontok elemzése segíti annak megértését, hogy a szépirodalom és a populáris kultúra hogyan járul hozzá a történeti emlékezet a lokális identitás formálódásához.
A tanulási sajátosságok összehasonlítása az aktivitási szint szempontjából különböző időskori életszakaszokban
Authors: Bajusz Klára , Virágh Viktória
Published: August 2023

Öregedő társadalmunknak fokozott figyelmet kell fordítania arra, hogy az idős korosztály tagjai milyen életminőségben, milyen testi, lelki és szellemi jóllétben élik életüket. Az idős korcsoportok társadalmi arányának növekedésével egyre alapvetőbb szükségletté válik a tudatos és sikeres idősödés, melynek megvalósításához intergenerációs együttműködés, hálózatos gondolkodás és az egész közösségre kiható szemléletváltás szükséges. Tanulmányunk célja, hogy összevesse a go-go, slow-go és no-go idősek tanulási sajátosságait, valamint az egyes célcsoportok idősoktatás-módszertani jellemzőit. Írásunk  hiánypótló, hisz a no-go életszakasz tanulási-tanítási kérdéseit a szakirodalom marginálisan kezeli, és komparatív szempontból sem vizsgálja az egyes aktivitási szakaszok tanulási karakterét. Tanulmányunkban kitérünk arra, hogyan alkalmazható az időskori tanulás a sikeres idősödés eszközeként. Jellemezzük a go-go, slow-go és no-go periódusokat, majd ezek alapján a következő szempontok szerint elemezzük, milyen sajátosságai vannak az egyes célcsoportoknak: tanulási motivációk, tanulási gátak, tanulási célok, a tanulás mint identitásmegőrzési eszköz, szelekció a képzések között, az előadó személyének szerepe, önállóság a tanulásban. Írásunk utolsó egységében röviden összehasonlítjuk a három periódus oktatásmódszertani elveit, különös tekintettel a no-go idősek képzési programjainak jellemzőire.
Rhythmic Entrainment Echoes in Auditory Perception
Authors: L’Hermite Sylvain , Zoefel Benedikt
Published: August 2023

Rhythmic entrainment echoes—rhythmic brain responses that outlast rhythmic stimulation—can demonstrate endogenous neural oscillations entrained by the stimulus rhythm. Here, we tested for such echoes in auditory perception. Participants detected a pure tone target, presented at a variable delay after another pure tone that was rhythmically modulated in amplitude. In four experiments involving 154 human (female and male) participants, we tested (1) which stimulus rate produces the strongest entrainment echo and, inspired by the tonotopical organization of the auditory system and findings in nonhuman primates, (2) whether these are organized according to sound frequency. We found the strongest entrainment echoes after 6 and 8 Hz stimulation, respectively. The best moments for target detection (in phase or antiphase with the preceding rhythm) depended on whether sound frequencies of entraining and target stimuli matched, which is in line with a tonotopical organization. However, for the same experimental condition, best moments were not always consistent across experiments. We provide a speculative explanation for these differences that relies on the notion that neural entrainment and repetition-related adaptation might exercise competing opposite influences on perception. Together, we find rhythmic echoes in auditory perception that seem more complex than those predicted from initial theories of neural entrainment.

SIGNIFICANCE STATEMENTRhythmic entrainment echoes are rhythmic brain responses that are produced by a rhythmic stimulus and persist after its offset. These echoes play an important role for the identification of endogenous brain oscillations, entrained by rhythmic stimulation, and give us insights into whether and how participants predict the timing of events. In four independent experiments involving >150 participants, we examined entrainment echoes in auditory perception. We found that entrainment echoes have a preferred rate (between 6 and 8 Hz) and seem to follow the tonotopic organization of the auditory system. Although speculative, we also found evidence that several, potentially competing processes might interact to produce such echoes, a notion that might need to be considered for future experimental design.
Phosphorylation controls spatial and temporal activities of motor‐PRC1 complexes to complete mitosis
Authors: Gluszek‐Kustusz Agata , Craske Benjamin , Legal Thibault , McHugh Toni , Welburn Julie PI
Published: August 2023

During mitosis, spindle architecture alters as chromosomes segregate into daughter cells. The microtubule crosslinker protein regulator of cytokinesis 1 (PRC1) is essential for spindle stability, chromosome segregation and completion of cytokinesis, but how it recruits motors to the central spindle to coordinate the segregation of chromosomes is unknown. Here, we combine structural and cell biology approaches to show that the human CENP‐E motor, which is essential for chromosome capture and alignment by microtubules, binds to PRC1 through a conserved hydrophobic motif. This binding mechanism is also used by Kinesin‐4 Kif4A:PRC1. Using in vitro reconstitution, we demonstrate that CENP‐E slides antiparallel PRC1‐crosslinked microtubules. We find that the regulation of CENP‐E ‐PRC1 interaction is spatially and temporally coupled with relocalization to overlapping microtubules in anaphase. Finally, we demonstrate that the PRC1–microtubule motor interaction is essential in anaphase to control chromosome partitioning, retain central spindle integrity and ensure cytokinesis. Taken together our findings reveal the molecular basis for the cell cycle regulation of motor‐PRC1 complexes to couple chromosome segregation and cytokinesis.
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite
Authors: Rosa Catarina , Singh Parul , Chen Patty , Sinha Ameya , Claës Aurélie , Preiser Peter R , Dedon Peter C , Baumgarten Sebastian , Scherf Artur , Bryant Jessica M
Published: August 2023

The complex life cycle of the human malaria parasite, Plasmodium falciparum, is driven by specific transcriptional programs, but it is unclear how most genes are activated or silenced at specific times. There is an association between transcription and spatial organization; however, the molecular mechanisms behind genome organization are unclear. While P. falciparum lacks key genome‐organizing proteins found in metazoans, it has all core components of the cohesin complex. To investigate the role of cohesin in P. falciparum, we functionally characterize the cohesin subunit Structural Maintenance of Chromosomes protein 3 (SMC3). SMC3 knockdown during early stages of the intraerythrocytic developmental cycle (IDC) upregulates a subset of genes involved in erythrocyte egress and invasion, which are normally expressed at later stages. ChIP‐seq analyses reveal that during the IDC, SMC3 enrichment at the promoter regions of these genes inversely correlates with gene expression and chromatin accessibility. These data suggest that SMC3 binding contributes to the repression of specific genes until their appropriate time of expression, revealing a new mode of stage‐specific gene repression in P. falciparum.
Sleep quality and burnout in higher education teachers
Authors: Barbosa Italo Everton Bezerra , Mallagoli Isabela Saura Sartoreto , Okuno Meiry Fernanda Pinto , Fonseca Cassiane Dezoti da , Belasco Angélica Gonçalves Silva
Published: August 2023

Objective: to evaluate the association of sleep quality and the presence of burnout syndrome with the epidemiological profile of higher education teachers. Methods: an observational, analytical, cross-sectional study of 140 teachers, using the Pittsburgh Sleep Quality Index and the Maslach Burnout Inventory. Results: in the sample, the majority was female (54.3%), aged between 26 and 40 years (58.6%). There was a predominance of teachers with a specialist title (48.6%), with a salary range of up to R$ 5,000.00 (85.7%), with two or more employment relationships (52.1%). It was found that teachers who received more than R$ 5,000.00 (p=0.003), with two or more jobs, classified the usual sleep efficiency as poor/feeble (p=0.027). However, those with good subjective sleep quality had lower scores in the Emotional exhaustion (p=0.005) and Depersonalization domains in relation to the syndrome (p=0.023). Conclusion: several factors contribute to the development of sleep-related disorders in teachers, making them more susceptible to the manifestation of burnout. Contributions to practice: the results can support preventive measures for the health of teachers and maintain the quality of their work activities, aiming to reduce the mediation effect of the variables that favor psychological exhaustion.
University Open to Older People: factors associated with the use of information and communication technologies
Authors: Scarponi Alice Pinheiro , Santos Natália Quevedo dos , Batista Denerval Mendez , Aranha Milena Ribeiro Mariucio , Aizava Paulo Vitor Suto , Bertolini Sônia Maria Marques Gomes
Published: August 2023

Objective: to identify the factors associated with the use of information and communication technologies by older students at a University Open to Older People. Methods: this was an analytical, cross-sectional study with 102 participants of both sexes. This was an analytical, cross-sectional study with 102 participants of both sexes. The study collected data from older people via web to characterize the socioeconomic and technological profile through a self-completed questionnaire. Results: the findings of the present study revealed the existence of a significant association between the frequency in higher education and the use of notebook (p=0.021) and smart TV (p=0.031). Additionally, the analysis observed an association between the monthly family income higher than four minimum wages and the use of tablet (p=0.026), smart TV (p=0.006) and printer (p=0.002) by the sample participants. Conclusion: education level and socioeconomic status were some intervening factors in the use of technologies by the older individuals enrolled in a University Open to Older People. Contributions to practice: the study provides information on the profile of older students regarding the main factors associated with the use of information technologies. With this, activities that enable greater integration and motivation of this population can be programmed and offered.
Sports celebrity endorsement impact on purchase intention
Authors: Moreira Francisco , Pereira Inês , Santos José Duarte , Pires Paulo Botelho
Published: August 2023

This research aims to study celebrity endorsement in the context of social media when done by sports celebrities and its influence on purchase intention. Four dimensions have been studied: word of mouth, brand image, brand trust, and brand attitude. By relating these variables, we seek to answer the following questions: Will consumers be influenced by a sports celebrity that they admire to buy a product/service from a brand that they support? Will the brand’s components be valued as a result of celebrity endorsement? Using a questionnaire shared on social networks, 303 valid answers have been obtained. Our statistical analysis has used a structural equation model and the results have been analyzed using SmartPLS software, which has confirmed all the model assumptions. Therefore, celebrity endorsement has an impact on brand image, word of mouth, brand attitude, and brand trust. Furthermore, it directly affects purchase intention. The effectiveness of celebrity endorsement has been verified in the context of social media and this research can thus help marketeers understand the importance of using sports celebrities to endorse brands. Implications for brands have been identified, based on the research results.
An Investigation of Entrepreneurial Orientation, Social Media Adoption and E-commerce on MSME Business Performance: An Empirical Study in Indonesia
Authors: Yacob Syahmardi , Sulistiyo Urip , Marzal Jefri , Siregar Ade Perdana , Mukminin Amirul
Published: August 2023

The COVID-19 pandemic has significantly impacted the health, economy, and social sectors, and micro, small, and medium-sized enterprises (MSMEs) worldwide, including in Indonesia. This paper examines the use of social media and e-commerce with an entrepreneurial orientation to enhance the business performance of MSMEs. The study should serve as a model for improving the quality of micro, small, and medium-sized enterprises in the Jambi Province, in Indonesia. The research employs quantitative and qualitative approaches. The latter method employs in-depth interviews, focus group discussions (FGDs), and observation, whereas the former uses the partial least squares method (PLS). The findings and discussions conclude that social media adoption positively affected the performance and entrepreneurial orientation of MSMEs during the said period. Similarly, e-commerce positively affected the performance and entrepreneurial orientation of MSMEs. Entrepreneurialism and social media adoption had a significant impact on the performance of MSMEs, and due to its entrepreneurial orientation, e-commerce influenced the performance of MSMEs.
The Effect of Different Surface Treatments on the Color Stabilities of Lithium Disilicate Material
Authors: DAĞ Onur Doğan , ALKAN DEMETOĞLU Göknil , KURT Ayşegül
Published: August 2023

Background: The aim of this study is to investigate the clinical acceptability of the color change that may occur in time about full ceramic materials used for aesthetic restorations, which are bonded after different surface conditioning processes, by measuring with spectrophotometer.

Methods: The lithium disilicate CAD material we used in our work was prepared with isomet in the form of 1-millimeter-thick specimens. Three random groups of 21 specimens were selected from the specimens. One of these groups was conditioned with phosphoric acid, which is recommended by the manufacturer. Er:YAG laser was applied to the second group. The third group was conditioned by Nd:YAG laser. Surface changes in the groups were evaluated by scanning electron microscope (SEM) and atomic force microscope (AFM). The specimens were bonded with the adhesive resin cement to the background material for color change measurement. The first color measurement of the bonded specimens was done by spectrophotometer. The specimens were aged at 10,000 cycles in the thermal cycle device. The second color measurement after aging was done with the same spectrophotometer.

Results: After aging with thermal cycle, there was a clinically acceptable color change in all groups. The Nd:YAG laser group presented better color stability (p
Evaluation of Dental Trauma Knowledge Levels of Cyclists in Turkiye
Authors: ÇULHA Emre , TUNÇ Fatma
Published: August 2023

Background: Cycling is a risky sport in terms of dental injury. Immediate treatment of traumatized teeth is very critical for the prognosis. This study aims to evaluate the knowledge levels and attitudes of cyclists in Turkey about dental trauma and its emergency treatment.

Methods: In the study, a total of 12 questions were asked in the online questionnaire directed to the participants in different cities in Turkey. The answers received were divided into three groups according to their cycling experience; Group 1: less than 5 years, Group 2: 6-10 years, and Group 3: more than 11 years, and evaluated with the Chi-square and Bonferroni multiple comparison tests. P value < 0.05 was accepted as statistically significant.

Results: According to the data obtained; It was determined that 31.8% of the participants in Group 3 and 10.4% of the participants in Group 2 did not use protective equipment while cycling (P
Farklı Remineralize Edici Ajanlar Uygulanan Başlangıç Çürük Lezyonlarına Üniversal Bir Adezivin Farklı Tekniklerle Uygulanmasının Makaslama Bağlanma Dayanımına Etkisi: İn Vitro Çalışma
Authors: KEDİCİ ALP Cemile , ARSLANDAŞ DİNÇTÜRK Beyza
Published: August 2023

Amaç: Bu çalışmanın amacı; All Bond Universal adeziv sisteminin farklı uygulama teknikleriyle (total-etch, aktif self-etch, pasif self-etch) farklı ajanlarla remineralize edilmiş (Remin Pro veya MI Paste Plus) mine yüzeyine uygulandığında makaslama bağlanma dayanımını ve yüzeylerde oluşan farklılıkları SEM ile değerlendirmektir.

Gereç ve Yöntemler: Çalışmamızda kullanılan 96 sığır dişi rastgele 12 gruba (sağlam mine, demineralize mine, remineralize edilmiş mine) ayrıldı, sağlam mine örneklerinin haricinde kalan gruplar için mine örnekleri 37°C'de 96 saat boyunca demineralizasyon solüsyonunda bekletildi, örneklerin bir kısmı remineralize edilmek (Remin Pro, MI Paste Plus) için kullanıldı. Mine örnekleri üzerine All Bond Universal total-etch, aktif self-etch, pasif self-etch teknikleriyle uygulandı ve rezin kompozit (Filtek Ultimate, 3M ESPE) ile restore edildi. Makaslama bağlanma dayanımı üniversal test cihazı İnstron kullanılarak test edildi. Elde edilen verilerin normal dağılmasından dolayı gruplar arasındaki karşılaştırmalarda iki yönlü varyans analizi (Anova testi), post hoc analizlerde Tukey HSD test kullanıldı. (p
The Bonding of Soft Lining Materials to The Denture Base: Meta-Analysis
Authors: TOSUN Büşra , YANIKOĞLU Nuran
Published: August 2023

Background: One of the biggest disadvantages of soft lining materials is that they deform over time and cause ruptures and fractures in the bonding with the denture base. To overcome these problems, the factors that weaken the bonding should be determined and measures should be taken accordingly. The aim of this study is to elucidate the factors affecting the bonding of soft lining materials to the denture base, in terms of dental base and soft lining materials, surface treatments and retention agents.

Methods: The keywords 'soft lining materials, dental base, bond strength' were written and searched using PubMed/Medline databases, and as a result, 54 research articles related to the current study were evaluated. Each article was classified in terms of the type of denture base and soft lining material, methods of surface treatment, retention agents, and bond strength.

Results: While retention in saliva and water bathing decreased the shear bond strength compared to the group without any retention agent, the application of cleaning agents increased the shear bond strength. The tensile bond strength varied according to the surface treatments, and the laser application showed the highest tensile bond strength. In terms of peel strength, the heat-treated group and the laser with chemical treatment applied group showed lower bond strength than the mechanical treatment and soaked group.

Conclusion: It was concluded that cleaning agents, laser application and mechanical treatments increased the tensile, shear and peel strength.
Restoratif Diş Hekimliğinde Çürük Önleme ve Tedavilerinde Nanoteknoloji Stratejileri
Authors: YILMAZ Cemile
Published: August 2023

Diş çürüğü en sık görülen ağız hastalığıdır. Diş çürüklerinin bakteriyolojik etiyolojisi, bu tür oral bulaşıcı hastalıkları önlemek için antibiyotik veya antimikrobiyal ajanların kullanımını teşvik eder. Sistemik antibiyotikler diş çürüklerini tedavi etmek için uzun süredir kullanılmaktadır. Bununla birlikte, diş çürüklerine karşı savaşmak için yeni antimikrobiyal ajanlar geliştirilmiştir. Nanoteknoloji, nanomalzemelerin kullanımı yoluyla tıp da dahil olmak üzere çeşitli alanlarda birçok heyecan verici ve yeni uygulamalar ortaya çıkmasını sağlamıştır. Nanopartiküllerin kullanımı artık diş enfeksiyonları ve hastalıklarının tedavisi ve önlenmesi için düşünülmektedir. Bu nanomalzemeler, diş çürükleri de dahil olmak üzere ağız hastalıklarını önlemek ve tedavi etmek için restoratif, protetik, endodonti, periodontal tedaviler ve implantasyonlarda kullanılan rezinler, metaller, seramikler vb. gibi malzemelere dahil edilebilir. Nanoteknoloji diş çürüklerini iki ana yaklaşımda tedavi eder. Diş çürüğü yönetimi için nanoteknoloji tabanlı stratejiler remineralize yaklaşım ve antibakteriyel yaklaşımdır. İlk yaklaşımda, kalsiyum fosfat, kalsiyum florür, hidroksiapatit ve florohidroksiapapit gibi florür ve kalsiyum salınım kabiliyetine sahip nanomalzemeler remineralizasyon adı verilen bir süreçte kullanılmaktadır. Gümüş, kuaterner amonyum polietilenimin ve çinko oksit nanopartikülleri gibi antibakteriyel nanomalzemelerin uygulanması ikinci yaklaşımdır. Bu iki yaklaşımın bir kombinasyonu daha iyi sonuçlar sunmak için de kullanılabilir. Bu derlemenin amacı, diş çürüklerinin gelişimini durdurmak ve önlemek amacıyla, oral patojenlerle mücadelede nanoteknoloji ile yeni ve geliştirilmiş dental ajanların kullanım, etki mekanizmaları hakkında en güncel bilgileri bir arada toplamaktır.
COVID-19 Pandemi Sürecinde Uzaktan Eğitimden Yüz Yüze Eğitime Geçiş Sonrasında Klinik Uygulamalar Yapmakta Olan Diş Hekimliği Fakültesi Öğrencilerinin Kaygı ve Depresyon Düzeylerinin Değerlendirilmesi
Authors: YAVUZ Esra , YILMAZ Selmi
Published: August 2023

Amaç: COVID-19 pandemi sürecinde alınan önlemler sonucunda, Türkiye’de bir süre uzaktan eğitime geçilmiş ve sonrasında tekrar yüz yüze eğitime devam edilmiştir. Bu dönemde öğrencilerde kaygı ve depresyon gözlenebilmektedir. Bu çalışmanın amacı, uzaktan eğitimden yüz yüze eğitime geçiş sonrasındaki dönemde klinik uygulamalar yapmakta olan diş hekimliği fakültesi öğrencilerinin, kaygı ve depresyon düzeylerinin değerlendirilmesidir.

Gereç ve Yöntemler: Çalışmaya Akdeniz Üniversitesi Diş Hekimliği Fakültesi’nde öğrenim görmekte olan 4. ve 5. sınıf öğrencileri dahil edildi. Öğrencilerin kaygı düzeyleri Spielberger Durumluk ve Sürekli Kaygı Ölçeği (STAI-I ve STAI-II) ile, depresyon düzeyleri ise Beck Depresyon Ölçeği (BDÖ) ile değerlendirildi. Verilerin analizinde SPSS versiyon 28 kullanıldı ve p
Technical quality of root canal treatment performed by undergraduate students using rotary instruments versus hand instruments: A Retrospective Study
Authors: TEKİN Alperen , ERDEM HEPŞENOĞLU Yelda , ERSAHAN Seyda , ARIKAN Nur Sena
Published: August 2023

Background: The technical quality of root canal treatment (RCT) may impact on the outcome. The quality of education received during undergraduate school may be linked to the quality of treatment provided in general dental practice.

Objective: To compare the technical quality of RCT where rotary or manual step-back canal preparatory technique was employed in an undergraduate dental clinic in Turkey. Additionally, the present study aimed to compare radiographically commonly seen complications in both instrumentation systems.

Materials and Methods: Dental records of 270 patients who received RCT undertaken by dental students were investigated by retrospective chart review. 565 root canals belonging to 270 patients were randomized into two groups [(rotary, n=280, and manual hand instruments, n=285)]. Root canal obturation was evaluated on the basis of the length of obturation being >2mm from the radiographic apex, with uniform radiodensity and good adaptation to root canal walls. Inadequate root canal obturation included cases containing procedural errors such as perforation, ledge, transportation, instrument separation. Descriptive statistics were used to define categorical variables (n, %) and the level of significance was set at 0.05.

Results: The technical quality of RCT performed by undergraduate dental students was classified as 'adequate' in 75% and 53.7% of the cases, respectively for rotary and manual groups, respectively (p < 0.05). The highest procedural errors were seen in molars. Occurrence of procedural errors differed significantly between the groups, being 6.4% in rotary group and 12.3% in manual group (p = 0.017). However, occurrence of ledge formation was higher in manual group than that of rotary group (p = 0.007).

Conclusion: In view of our findings, RCT performed by undergraduate dental students using rotary instrumentation systems is of higher technical quality and also has fewer procedural errors than manual instrumentation.
Modifiye Üçlü Antibiyotik Patının Uzaklaştırılmasında Fotonla İndüklenmiş Fotoakustik Dalgalanma ile Farklı İrrigasyon Aktivasyon Rejimlerinin Kombinasyonunun Karşılaştırılması
Authors: AKMAN Melek , TERLEMEZ Arslan , AKBULUT Makbule Bilge , ARI AYDINBELGE Hale
Published: August 2023

Amaç: Bu çalışmanın amacı, kök kanallarından modifiye üçlü antibiyotik patının (mTAP) çıkarılmasında foton kaynaklı fotoakustik dalgalanma (PIPS) tekniği ile farklı irrigasyon aktivasyon rejimlerinin kombinasyonunun etkinliğini karşılaştırmaktır.

Gereç ve Yöntemler: Yüz beş adet çekilmiş insan mandibular-premolar dişler ProTaper döner eğe kullanarak prepare edildi. Kök kanalları mTAP medikamenti ile dolduruldu ve 4 hafta sonra kökler kullanılan irrigasyon rejimlerine göre rastgele 7 gruba (n=15) ayrıldı: Self-Adjusting File (SAF), Pasif-Ultrasonik-İrrigasyon (PUI) , EndoAktivatör (EA), SAF+EA, SAF+PUI, PUI+EA, PIPS. 3 dişte mTAP kaldırılmadı (pozitif kontrol) ve diğer 3 diş mTAP ile doldurulmadı (negatif kontrol). Kökler uzunlamasına ikiye ayrıldı ve kalan mTAP miktarı, 4 dereceli bir skorlama sistemi kullanılarak 20x büyütme ile değerlendirildi. Veriler Kruskal-Wallis ve Mann-Whitney U testleri kullanılarak değerlendirildi.

Bulgular: Tüm deney grupları arasında istatistiksel olarak anlamlı farklılık tespit edildi. PIPS, SAF, SAF+EA ve SAF+PUI, mTAP'yi kök kanalından çıkarmada PUI ve PUI+EA'dan önemli ölçüde daha iyi performans gösterdi (P=0.000). EA orta etkinlik gösterdi. Apikal ve orta üçte birlik kısımda PUI ve PUI+EA ve koronal üçte birlik kısımda PUI önemli ölçüde daha kötü performans gösterdi (P
Diş Hekimliği Fakültesinde Mavi Kod Uygulama Sonuçlarının Değerlendirilmesi
Authors: MENZİLETOĞLU Dilek , ESEN Alparslan
Published: August 2023

Amaç: Mavi kod; hastanelerde acil tıbbi müdahaleye ihtiyaç duyan hastalara, hasta yakınlarına ve tüm hastane personeline en kısa sürede profesyonel ekiple müdahale edilmesini sağlayan acil durum yönetimidir. Uluslararası renkli kod uygulamalarında mavi rengin ortak kullanıldığı tek koddur. Tüm dünyada tek ve aynı renk kullanılmaktadır. Bu çalışmanın amacı; diş hekimliği fakültesinde mavi kod uygulamalarının önemini, etkinliğini ve uygulama sonuçlarını değerlendirmektir.

Gereç ve Yöntemler: Necmettin Erbakan Üniversitesi Diş Hekimliği Fakültesi’nde Ocak 2020- Haziran 2022 tarihleri arasında Mavi Kod çağrısı verilen 83 hastanın verileri retrospektif olarak incelendi. Hastaların yaşları, cinsiyetleri, sistemik hastalıkları, çağrının hangi bölümden yapıldığı, ekibin hastaya ulaşma süresi, çağrı sebebi, yapılan müdahale ve uygulamanın sonuçları araştırıldı.

Bulgular: Çalışmada 83 hastanın Mavi Kod Bildiri Formu değerlendirildi. Hastaların 53’ü kadın (%63.85) ve 30’u (%36.15) ise erkekti. Yaş ortalaması 32.15 ± 19.53 idi. Çağrıların %25.30’unun pedodonti bölümünden verildiği ve Mavi Kod Ekibinin ortalama 2.38 ± 1.52 dakikada (min/mak: 0.25 / 5.78 dakika) olay yerine ulaştığı tespit edildi.

Sonuç: İki yıllık zaman periodunda herhangi bir arrest ya da pre-arrest vakası olmadığı görüldü. Ekibin her çağrıyı ciddiye alarak olay yerine gittiği, gerekli müdahaleyi yaptıkları ve doğru yönlendirmeler ile istenmeyen hayati risk olasılığını ortadan kaldırdığı sonucuna varıldı.
Cytotoxicity Evaluation of Different Types of CAD/CAM Blocks
Authors: COŞKUN Fikret Özgür , AKBABA Giray Buğra , ATALA Mustafa Hayati , ÖZÜDOĞRU Semanur
Published: August 2023

Aim: The aim of this study is to determine the cytotoxic effects of Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) blocks produced by different companies on human peripheral blood lymphocytes by MTT assay.

Methods: Six different CAD/CAM materials were investigated: feldspar ceramic VM (Vitablocks Mark II ), resin nano-ceramic LU (Lava Ultimate), hybrid ceramic C (Cerasmart), leucite-reinforced ceramic LRF (GC LRF), zirconia-reinforced lithium silicate ceramic VS (Vita Suprinity), polymer-infiltrated ceramic-network VE (Vita Enamic). A total of 36 disc-shaped samples (Ø: 5 mm; h: 2 mm) were prepared from commercial blanks and blocks. Cell proliferation and cytotoxicity were assessed at 24h and 48h using MTT assay. The data were statistically evaluated with the Two-way ANOVA test (p < 0.05).

Results: MTT viability data at 24 h showed that group VM and LU blocks were mildly cytotoxic, but there was no statistically significant difference when compared with other groups (p>0.05). It was determined that all blocks caused cell proliferation after 48 hours of exposure (p>0.05). It has been shown that all blocks whose cytotoxic effects were investigated did not cause any toxic effects (except VM and LU for 24 h) at different application times (24 h and 48 h).

Conclusion: Based on the results obtained and the limitations of the current in vitro study, the tested materials were not cytotoxic. Only VM and LU caused negligible cytotoxicity at 24-hour exposure.
Comparison of Mechanical Properties of Aged All-Ceramic Materials
Authors: TEMİZCİ Tugba , TUNCDEMİR Ali Riza
Published: August 2023

Background: Our research aimed to compare the biaxial flexural strength of glass ceramic and two different monolithic zirconias after aging, examine the fracture surfaces with scanning electron microscopy (SEM) and perform elemental analysis with energy dispersive spectroscopy (EDS).
Methods: Two types of monolithic CAD/CAM materials (Katana UTML and Prettau Anterior) and a lithium disilicate material (IPS emax Press) were selected for this study. All samples were aged with a thermal cycle of 10000 cycles. The biaxial flexural strength of the disc specimens was determined using the three-ball piston test and a universal testing machine. Biaxial flexural strengths were compared for each group (n = 10). All fractured samples were examined by SEM and elemental analyzes were performed with EDS. Data were analyzed by 1-way ANOVA and Tukey post hoc (p<0.05).
Results: Prettau Anterior showed a statistically significant difference between the other groups (p<0.05). Following Prettau Anterior (1141.81 MPa), IPS Emax Press (278.86 MPa) and Katana UTML (216.14 MPa) showed biaxial flexural strength, respectively.
Conclusion: Compared to the other materials evaluated, Prettau Anterior had much higher biaxial flexural strength. Katana UTML and IPS emax Press show similar strength over the long term. It is seen that the chemical structure of the materials has an effect on the mechanical capacity.
KEYWORDS: Biaxial Flexural Strength, Lithium Disilicate Glass-Ceramic, Monolithic Zirconia
Çocuklarda Flor Uygulamaları Hakkında Bilgi Veren İnternet Sitelerinin İçeriklerinin ve Güvenilirliklerinin Değerlendirilmesi
Authors: AKSOY Merve , BAL Cenkhan
Published: August 2023

Amaç: Yürütülen çalışmanın amacı internet sitelerindeki flor konulu paylaşımların içerik analizini yapmak ve güvenilirliklerini değerlendirmektir.

Gereç ve Yöntem: Google Chrome tarayıcına 2 anahtar kelime (flor vernik zararlı mı?, çocuklarda flor uygulamaları) girilmiş ve her iki terim için ilk 50 sitenin linki kaydedilmiştir. Türkçe bilgi içermeyen siteler, dublikasyon olanlar, yalnızca video kaydı veya linki olan siteler, soru-cevap forumları, bilimsel yayın ve ders notu linkleri, reklam ve pazarlama amaçlı siteler çalışma dışı bırakılmıştır ve kalan 73 site Discern güvenilirlik analizi ile içerik analizini içeren bir incelemeye tabi tutulmuştur. Elde edilen veriler SPSS 25 programı ile analiz edilmiş, p