bluuebunny/crossref_metadata_2025 huggingface dataset:
High-quality production of red plum apricot in semiarid Loess Hilly region of China
Authors: Zhongsheng Guo
Published: January 2024

Red plum apricot is a deciduous fruit tree and the best cash forest in semi-arid Loess hilly regions of China. Since 1995, the distribution area of the apricot has spread in most of the water-limited regions, in China, and the yield and benefits of red plum apricot increase dramatically. Since 2017, China put forward high-quality development, and red plum apricot must carry out high-quality production. But, as the red plum apricot tree grows, low temperatures and frost, hazards of heart-eating insects and soil drying will appear, which seriously influence the yield, quality, and benefits of red plum apricot in turn. However, there are few reports on the method for High-quality production of red plum apricot. In this study, the effectiveness of different methods of controlling low temperature and frost and hazards of heart-eating insects and soil drying was estimated. The results show that the greenhouse method is the better method for controlling Low temperature and frost, spraying Beta-cypermethrin still is the better method for controlling Hazards of heart-eating insects. When the soil water resource in the maximal infiltration depth is lower than the soil water resource use limitation by red plum apricot, the plant water relationship enters the key period of plant water relationship regulation. The ending time of the critical period of plant water relation regulation is the failure time of plant water relation regulation. When the current plant density is more than the soil water vegetation carrying capacity, the plant-water relation should be regulated, and then the vegetative growth and reproductive growth on the appropriate leaf quantity when the current plant density is equal to the soil water vegetation carrying capacity and the leaf fruit relation.
Protocol2_In vitro transcription.pdf v1
Authors: not provided angelica.gonzalez
Published: January 2024

In vitro transcription
Advancements in base isolation for seismic mitigation: Perspectives on elastomeric and lead rubber bearings
Authors:   Department of Civil Engineering, Indian Institute of Technology-BHU, Patel Dhirendra , Mourya Vishal Kumar ,   Department of Civil Engineering, Indian Institute of Technology-BHU, Pandey Gaurav ,   Department of Civil Engineering, Indian Institute of Technology-BHU, Kumar Rajesh ,   Department of Civil Engineering, Indian Institute of Technology-BHU
Published: January 2024

Base isolation represents an environmentally sustainable and highly effective technique for mitigating structural responses to strong seismic forces generated by plate boundary tectonic activities. Its primary benefits include preventing structural collapse, minimizing property damage, and safeguarding human lives during severe earthquakes. This passive, energy-efficient approach is often complemented by supplementary dampers to further reduce seismic impact. This study provides a comprehensive overview of elastomeric and lead rubber isolators, covering their theoretical, experimental, and numerical aspects. The paper examines the seismic response of structures equipped with elastomeric and lead rubber bearings, including a discussion of their pros and cons. This paper presents the comparison of fixed base and rubber isolated base in SAP 2000 to assess the effectiveness of base isolation. Additionally, it presents findings from shaking table tests, relevant building codes, and practical applications, considering the impact of events beyond initial design parameters. The review delves into the historical evolution of elastomeric and lead rubber-bearing systems, offering valuable insights into their contemporary understanding. Furthermore, the paper introduces three-dimensional isolators designed to attenuate ground motion responses in both horizontal and vertical directions. It investigates the effects of soil-structure interaction and evaluates isolator responses under blast and impact aircraft loading conditions. Notably, specific types of bearings exhibit exceptional energy dissipation capabilities during catastrophic seismic events, leading to reduced floor acceleration and inter-storey sway at critical levels. In conclusion, the study offers future recommendations and identifies potential constraints in this field
Application of nanotechnology in clinical dentistry type of manuscript: Review article
Authors: Jain Sanjoli , Singla Mamta
Published: January 2024

Over the years, dentistry has undergone multiple phases of revolution, increasing its reliability and patients' comfort. One of these, "NANOTECHNOLOGY," has the potential to fundamentally alter how management and diagnostics are performed. A preliminary vision by Feynma led to the conception of nanotechnology in 1959. Since the dimensions of nanotechnology have been understood, it has been suggested that nanotechnology is the sector with a great potential for development considering its implications in the different fields of medical and dental sciences.

Several nanotechnology advancements have been applied in the field of oral health over the past 10 years, however many of these applications are still in their early years. Just a few of the several dental applications of nanotechnology include dentition renaturalization, treatment for dentin hypersensitivity, full-visit orthodontic realignment, covalent bonding of diamondized enamel, enhanced root canal sealant properties, and currently ongoing oral health maintenance using mechanical dentifrobots.

Numerous artificial nanoparticles, such as hydroxyapatite, bio glass, titanium, zirconia, and silver nanoparticles, are recommended for dental restoration. If executed correctly, the discipline of nanotechnology has the potential to significantly benefit human society by enhancing health, better utilizing natural resources, and reducing environmental pollution. Every procedure in dentistry in the future will be performed with instruments and technologies based on nanotechnology.
Silver diamine fluoride – ‘The silver bullet’ in pediatric dentistry: An overview of past, present and prospects
Authors: Jagtap Vijaya , Padawe Dimple , Takate Vilas , Dighe Kishor , Rathi Gauri , Wankhade Ajinkya
Published: January 2024

Various fluoride-containing topical agents like sodium fluoride, acidulated phosphate fluoride, Silver fluoride, and Silver diamine fluoride (SDF) have also been developed to prevent and intercept dental caries, particularly in children. SDF in 38% concentration for preventing and arresting dental caries in children. SDF is applied exclusively to carious lesions, both cavitated and non-cavitated, forming a protective layer on demineralized enamel and dentin. This layer enhances resistance to acid dissolution and enzymatic digestion of collagen, promoting mineralization and the formation of hydroxyapatite and fluorapatite SDF is a versatile treatment option for caries management, offering benefits in various clinical scenarios, including difficult access cases, high caries risk patients, and prevention of pit and fissure caries. The present article discusses the utility of SDF in dentistry, with an emphasis on pediatric dentistry
A periodontist’s favourite: The platelet concentrates
Authors: Roshan Suhana , Thomas Deepak , Suresh D K  , Ahila D  , Radhakrishnan Reshma
Published: January 2024

The era of platelet concentrates have been ever evolving in the field of regeneration. Exquisite research regarding these have led to it’s usage in various fields apart from periodontics. The controlled release of growth factors, excellent biocompatibility and cost effective preparation have put in demand the second generation of platelet concentrates-the platelet rich fibrin. Recent research has led to the evolution of various forms of PRF that has the potential of wound healing and regeneration with respect to the types of the growth factors released. This article aims to review the evolution and recent advances of platelet concentrates.
A rare case report of natal tooth, neonatal tooth (dentitia praecox) and fibrous hyperplasia (Riga fede disease) of same newborn patient
Authors: Ghoshal Nanda Kishore , Singh Susanchita
Published: January 2024

The natal tooth is present at the time of birth and neonatal tooth erupts within first 30 days of birth. Both are considered as an anomaly of a child. Due to mechanical irritation of those teeth there may be a chance of traumatic ulceration on the ventral surface of teeth known as Riga Fede disease (RFD). The term is used for the lesion in case of child less than two years old. The age above two years the term coined as traumatic granuloma. It may lead to a serious condition where the child denies to take any food or to suck breast milk due to the painful condition. In the present case study 21 days old newborn came to the clinic with a complaint of ulcerative lesion on the ventral surface of the tongue which was interfering in suckling. On examination 8 X5 mm ulcer extending from anterior border of the tongue to lingual frenum was found along with two mandibular incisors. He was detected with natal tooth (at the time of birth) and neonatal tooth (erupted on 16th day) which caused RFD.The case report throws some light on a possible treatment approach for successful management of the condition.
Successful treatment of an impacted maxillary canine using closed surgical exposure: A case report
Authors: Tazi Perla
Published: January 2024

Impaction of a maxillary canine is a common tooth transposition, being the second most frequently impacted tooth after third molars. Management of such cases typically require a multidisciplinary approach, combining surgery with orthodontics. Presented is a case involving a 12-year 7-month-old male patient with an impacted right maxillary canine, premature loss of the second deciduous right maxillary molar and hypoplasia of the maxilla. Treatment included extraction of the premolars with surgical exposure and subsequent guided eruption of the impacted canine into the tooth arch.
Clinical encounters of giant cell fibroma: A comprehensive report on two distinct cases, exploring varied clinical presentations
Authors: Ramdurg Praveenkumar , Ramesh Saahil , Srinivas Naveen , Amaran E.G. Yog Naag , Puranik Surekha R
Published: January 2024

A giant-cell fibroma (GCF) is a benign, localized mucosal mass composed of fibrous tissue that exhibits clinical similarities to other fibro-epithelial growths. Its differentiation from other lesions relies on its distinctive histopathological characteristics. GCF is a rare oral fibrous lesion, often misdiagnosed as other fibrous growths. The first case involves a 24-year-old female with a GCF located near mandibular buccal gingiva. The second case centers on a 14-year-old boy who developed GCF on the incisive papilla region. These cases shed light on the diverse clinical manifestations and histopathological markers used in the diagnosis of GCF. The report delves into the clinical presentation, histological features, and differential diagnoses, offering valuable insights for oral healthcare professionals. Understanding the occurrence of GCF on different aspects of the gingiva is crucial for accurate diagnosis and effective treatment. This report contributes to the growing body of knowledge regarding this rare oral lesion and emphasizes the importance of considering GCF in the differential diagnosis of gingival growths.
Clinico-mycological profile of fungal infections in a tertiary care hospital
Authors: Gupta Veenu , Singh Monica , Mahajan Rajesh , Chaudhary Jyoti , Aggarwal Manisha
Published: January 2024

The fungal infections are increasing at high rate especially in immune-compromised patients and elderly population. In high risk population, antifungal resistance is becoming a major concern. Antifungal susceptibility testing is important for appropriate management and better outcome of patients.

The aim of the study was to know clinico-Mycological profile of fungal infections in admitted patients.

This prospective study was carried out in a tertiary care hospital. Various samples were received from patients with suspected fungal infections. All samples were inoculated on SDA except blood & body fluids which were directly inoculated into blood culture bottles and processed in BACTEK/BacTAlert system. Fungal infections were characterized and antifungal susceptibility was done for yeast isolates with VITEK-AST panel.

: Out of total 19698 patients suspected of fungal infection, fungal infection was seen in 365 patients , 100% susceptibility was seen to Fluconazole and Echinocandins. Whereas in NAC (non-albicans ), 72.5% susceptibility was seen to fluconazole and Voriconazole (82.5%).

Antifungal resistance is major cause of morbidity and mortality. Prompt diagnosis and antifungal susceptibility will offer the early appropriate treatment and better clinical outcome of patient.
Multiple microbial coinfections occurred during COVID-19 pandemic
Authors: Kumar Maneesh , Kumar Ratnesh , Kumari Arti , Topno Roshan Kamal
Published: January 2024

The COVID-19 pandemic brought to light a complex challenge: the occurrence of multiple microbial co-infections in affected individuals. In addition to the primary infection caused by the SARS-CoV-2 virus, patients often had to contend with secondary infections caused by bacteria, viruses, and fungi. This complicated interaction of pathogens has presented significant clinical, diagnostic, and therapeutic hurdles. It has been observed that co-infections can exacerbate disease severity and complicate treatment strategies, necessitating a more comprehensive approach to patient care. In addition, distinguishing between viral and bacterial/fungal coinfections based on clinical symptoms alone remains a difficult task, underscoring the need for advanced diagnostic tools. The emergence of coinfections has also heightened concerns about antimicrobial resistance due to the widespread use of antibiotics and antifungals, underscoring the importance of prudent antimicrobial stewardship. As the pandemic continues to evolve, understanding, diagnosing, and effectively managing these multiple microbial coinfections have become critical imperatives for healthcare systems and researchers worldwide. The present review illustrated the past occurrence of various microbial infections that co-existed with the COVID-19.
Prevalence of carbapenem-resistant Enterobacterales (CRE) in Somalia: A systematic review and meta-analysis
Authors: Mude Abdirasak Sharif Ali , Nageye Yahye Ahmed , Irekeola Ahmad Adebayo
Published: January 2024

Antimicrobial resistance remains a major challenge in public health. Many reports of resistance to common antibiotics have been documented. The carbapenems are one of the last line antibiotics against many members of the . However, the actual prevalence of carbapenem-resistant in Somalia is unknown. Thus, this present investigation was done to ascertain the actual prevalence. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline in the conduct of this study. Searches were conducted in electronic databases such as PubMed, Web of Science, Scopus, ScienceDirect, and Google Scholar to find published articles providing information on the prevalence of carbapenem-resistant in Somalia. Data were extracted and analyzed using the OpenMeta analyst software. Study quality was evaluated using the JBI prevalence tool. The resistance rate of to carbapenems were estimated using the random-effect model. A pooled resistance rate of 4.3% (95% CI, 2.5–7.2) was obtained for imipenem, 2.8% (95% CI, 0.8–8.8) for meropenem, and 13.9% (95% CI, 3.1–44.7) for ertapenem. The heterogeneity test showed low heterogeneity, except for studies contributing to the estimated resistance to ertapenem which had a high heterogeneity (I=91.52%; Q=11.788; p<0.001). This first systematic review and meta-analysis suggests that carbapenem antibiotics can be relied on as last line antibiotics to treat infections in Somalia.
Clinicohematological and drug prescription details in children affected with malaria: A retrospective study from a tertiary hospital of an endemic region in India
Authors: Jakribettu Ramakrishna Pai , Abraham Soniya , Daddibavi Akkamma , Bhandari Ganesh , Palatty Princy Louis , Baliga Manjeshwar Shrinath
Published: January 2024

Malaria is a life threatening plasmodial infection transmitted by infected female Anopheles mosquitoes. It infects mainly the reticulo-endothelial system and causes derangement in the hematological parameters. This study was undertaken to study the Clinicohematological and audit of drug prescription in children affected with malaria attending a tertiary care hospital at Mangalore in Karnataka state of India.

This was a retrospective study conducted in a tertiary care hospital among paediatric patients (<18 years of age) who were diagnosed with malaria during the study period. All the clinical details and other laboratory parameters were collected from the medical records and the lab parameters compared with control group, and statistical analysis was done. The mean, standard deviation was done for all the parameters and compared with control cases, using ANOVA /Kruskal Wallis test. The p value < 0.05 were considered as significant.

: A total of 290 children (males 182: females 108, 2:1) were included in the study, 204 (70.3%) patients had , mixed malaria 71 (24.5%) and 15 (5.2%) had . The Majority of the patients (179, 61.72%) belonged to the age group of 11-16 years (Table 1). Among the 290 children diagnosed with malaria, all had fever. Vomiting (89, 30.7%) was second most common symptom. The haemoglobin, and total leucocyte count was reduced in all patients, whereas the Erythrocyte Sedimentation Rate (ESR) was significantly higher in the infected cases. There was significant thrombocytopenia seen mainly in falciparum group. The liver and renal functions were deranged in infected cases. Among the 204 vivax group of patients, chloroquine (187, 91.67%) was the most frequently administered drug. All patients with and mixed group were treated with Artemether. Anti-hypnozoites drug, i.e. Primaquine were administrated to all vivax and mixed malarial patients as per guidelines for 14 days.

The study area is a well document endemic region forvivax malaria and our results agreed to previous reports in this study with the paediatric age group. The audit of drug prescriptions suggests that the drugs prescribed were as per guidelines in majority of the children.
A multiple logistic model for prediction of urinary tract infections in an urban community: A public health perspective
Authors: Jain Neelam , Bhargava Kanika , Prasad Jagdish , Morlocan Alexandru-Atila , Nath Gopal , Bhargava Amit , Khinvasara Palak , Yadav Ragini , Aseri G.K.
Published: January 2024

Urinary tract infection (UTI) is one of the most common infectious diseases globally. A lot of clinical research has been done on UTI patients, but a questionnaire-based study on UTI is scarce.

A cross-sectional study was conducted on outpatients with a high suspicion of uncomplicated UTI in Hayes Memorial Mission Hospital at Prayagraj (Eastern part of Northern India) to find out the frequency of symptoms and predisposing factors and their relationship towards the prediction of UTI.

Logistic regression analysis showed a significant association between UTI and some of the variables. Also, the factors responsible for the occurrence of UTI are “gender”, “how many times you urinate from morning till night”, “a sudden desire to urinate, which is difficult to hold”, “weakness of urinary stream”, “splitting or spraying of the urinary stream” and “fever”. A statistical model (multiple logistic model) has been also established for the prediction of UTIs with an accuracy of 82.2%. It is also observed that the prevalence rate (odds ratio) of UTI in females is 2.38 times that of males.

The study created a screening questionnaire for patients suspected of having UTI. A multiple logistic model has been established for the prediction of UTI which can be instrumental for clinicians from a public health perspective in the management of Urinary Tract Infections in this era of escalating AMR.
Empiric therapy for community acquired urinary tract infection in an era of increasing antimicrobial resistance
Authors: Anam Bushra , Mustafa Maimoona , Anjum Iqra
Published: January 2024

Community-acquired urinary tract infections (CA-UTIs) are widespread bacterial infections often necessitating empirical antibiotic therapy. However, the escalating antimicrobial resistance (AMR) poses a grave threat to treatment efficacy.

This study aims to assess the prevalence of AMR in uropathogens causing CA-UTIs and its implications for empirical therapy.

The study analyzed data from a tertiary care hospital, to determine AMR rates in common uropathogens, including and . Resistance levels to key antibiotics, such as Ampicillin, Ciprofloxacin, and Norfloxacin, were evaluated.

Significant resistance rates were observed in uropathogens, with and showing marked resistance. Notably, resistance to commonly prescribed antibiotics like Ampicillin, Ciprofloxacin, and Norfloxacin was widespread, highlighting the severity of the AMR crisis.

The increasing AMR in CA-UTIs calls for a comprehensive approach. Strategies including local resistance pattern monitoring, antimicrobial stewardship programs and the recommendation of drugs like nitrofurantoin (with lower drug resistance potential) are crucial to maintain the effectiveness of empirical therapy. This study underscores the urgent need for collaborative efforts to address AMR, ensuring effective CA-UTI management and safeguarding public health.
Renegotiating Work-Home Boundaries: Reconciliations of Remote Work and School During COVID-19
Authors: Karhu Mari , Häkkilä Jonna , Kalving Matilda , Mäkiranta Mari , Colley Ashley
Published: January 2024

This article contributes to understanding the radical transformation of everyday lives when parents’ remote work and children’s remote school were reconciled in homes during the early moments of the COVID-19 pandemic in 2020. The dataset comprises an online survey (n = 92) plus interviews, online diaries, and sampled experiences from 16 Finnish remotely working parents. Identified challenges to the parents’ remote work included interruptions and fragmentation of work tasks, non-optimal work ergonomics, and rescheduling of work times. We present the strategies parents used to create new rhythms and routines, a shared space under the same roof, peace, and privacy for daily work and school, as well as managing multiple simultaneous social roles. Parents’ rich experiences provide insights into the early steps of COVID-19-catalyzed remote work. Thus, the paper offers a reference point for exploring potential development trajectories in the increasingly common hybrid work setting.
Endotracheal Intubation of COY1D-19 Patients
Authors: Hussain Khan Zahid
Published: January 2024

The Article Abstract is not available.
Block Facilitatory Effects of Perineural Dexmedetomidine in Supraclavicular Brachial Plexus Block with Ropivacaine: Does Dexmedetomidine Has Perineural Site of Action? A Randomized, Controlled and Triple Blind Study
Authors: Sharmal Vinay Kumar , Yadav Pratima , Tak Mathura Lal
Published: January 2024

Background: Although nerve block facilitatory effects of dexmedetomidine when used as a perineural adjunct to local anesthetics in supraclavicular brachial plexus blocks are well recognized in multiple studies, but whether this action is at directly on peripheral nerve fibers or is at central level after systemic absorption is unclear. Aim of this study was to evaluate the effect of adding dexmedetomidine 1 microgram/kg to ropivacaine 0.5% in supraclavicular brachial plexus block in terms of duration of analgesia and 24hour cumulative analgesic requirement and to test the hypothesis whether the effect of dexmedetomidine, is due to direct local action on nerve plexus or is centrally mediated after systemic absorption.
Methods: 105 patients of ASA grade I and II of either sex undergoing upper limb orthopedic surgeries were divided in 3 groups of 35 patients in each group. Group Rc (control group) received supraclavicular block with 30ml of 0.5% ropivacaine and intravenous infusion of 30ml of normal saline; group RDexP received supraclavicular block with 30ml solution of 0.5% ropivacaine+ dexmedetomidine 1mcg/kg and intravenous infusion of 30ml of normal saline; and group RDexIV received supraclavicular block with 30ml of 0.5% ropivacaine and intravenous infusion of 30ml of normal saline solution containing dexmedetomidine 1mcg/kg. Primary outcome was duration of analgesia and 24hour cumulative analgesic requirement.
Results: The demographic data were comparable in all three groups. Duration of analgesia was longest in group RDexP followed by group RDexIV and least in control group. 24hour cumulative analgesic requirement was least in group RDexP and maximum in group R. 2 patients, one from each group RDexP and group RDexIV reported bradycardia and 6 patients from group RDexIV reported hypotension.
Conclusion: We conclude that action of dexmedetomidine is most probably peripheral on brachial plexus nerve fibers directly rather than centrally mediated after systemic absorption
CAO Recovered in the General Intensive Care Unit: Epidemioclinical Characteristics and Mortality Factors in a Sub-Saharan African Country
Authors: Bekoin-Abhe Chake Maria Josiane , Etienne Bazago Goulai Bi You , Théodore Coulibaly Klinna , Paterne Mobio Michael , Vianney Bedié Yao
Published: January 2024

Background: Cardiac arrest in the operating room (CAO) is a serious accident of often rare epidemiology.
Methods: Retrospective, descriptive and analytical study from 2012 to 2021 in the multipurpose intensive care unit of the Cocody University Hospital in Abidjan, including all patients who presented a recovered CAO.
Results: The prevalence was 1.5% (89 out of 5730 admissions). The mean age was 33.5 ± 26 years (13-81). The sex ratio was 0.1. The medical history was mostly hypertension (22.5%). Patients were classified ASA ≥ III (52.8%) for urgent surgery (52.8%) under spinal anesthesia (56.6%). CAO occurred mostly at anesthetic induction (44.3%). The causes were mainly persistent arterial hypotension (54.7%) and hemorrhagic shock (30.2%). Medical CPR was performed in 94.8% of cases in the operating room before transfer to the intensive care unit. The mean duration of LowFlow was 4.5±1.8 minutes (3-12). On admission, the mean Glasgow score was 6.3±4.4 (3-11). Treatment consisted of continued CPR. The mean stay was 3.1±2.9 minutes (1-12). The death rate was 60.4%. ASA class >3, urgent procedure, general anesthesia, presence of NA alone, Gl score ≤ 7, and Low Flow duration> 5 minutes were predictive of mortality (p < 0.05).
Conclusion: strengthening of material resources and continuous training in extreme emergency situations for anesthesia personnel could optimize the prognosis of CAO.
The Effect of Premedication with Oral Acetaminophen on the Prevention of Localized Pain Resulting from Intravenous Propofol Injection: A Randomized Double Blind Placebo Clinical Trial
Authors: Mousavi S Mohsen , Yekta Reza Atef , Heroabadi Arash
Published: January 2024

Background: Propofol is one of the most widely used medications in anesthesia and intensive care. Propofol Intravenous injection is painful for patients at the injection site. The aim of this study was to determine the effect of premedication with oral acetaminophen in prevention of local pain caused by intravenous injection of propofol.
Methods: This study was a double-blind randomized controlled trial. Data were collected from July 2020 to July 2021 in Shariati Hospital. All stages of premedication and induction of anesthesia were the same in all three groups of patients. Pb, P500 and P1000 groups (patients with oral placebo, 500 or 1000 mg of oral paracetamol, respectively) received the medication 1 hour before transfer to the operating room.
Results: In this study, 150 patients were included. 44.7% were men, 55.3% women, and mean age of patients was 36.82 ± 10.24. The highest severity of reported pain was in the group of patients receiving placebo. Patients receiving 1 gram of acetaminophen had the lowest reported pain. Patients receiving 500 mg of acetaminophen reported significantly less pain than patients receiving placebo and more pain than patients in the group receiving 1 g of acetaminophen. Age, gender and weight did not have any significant effect on the pain severity.
Conclusion: When compared to placebo, the use of oral acetaminophen as a premedication considerably lowers discomfort induced by intravenous propofol infusion. A dosage of 1 g of oral acetaminophen is more effective than 500 mg in decreasing pain. The level of pain and acetaminophen's pain-relieving effects were not affected by age, gender or weight.
Recurrent Laryngeal Nerve Injury Following Thyroidectomy Challenges to the Anaesthesiologist
Authors: Subramanian Selvamani , Murugesan Vasanthakumar , Santhanam Gayathri
Published: January 2024

Injury to the Recurrent Laryngeal Nerve is uncommon, but one of the complications of thyroidectomy.
We report a case of 40 years old female, who underwent total thyroidectomy, following which developed recurrent laryngeal nerve injury and vocal cord palsy, which was diagnosed immediately and managed successfully.
A Gentle Introduction to Cross-Cultural Adapting of Questionnaires in Medical Research
Authors: Madadizadeh Farzan , Zare Forouzan
Published: January 2024

The Article Abstract is not available.
Analysis of the Epidemiological Trend of Tuberculosis in Sistan and Baluchestan Province during 2015-2019
Authors: Khammarnia Mohammad , Daghighi Marzieh , Peyvand Mostafa
Published: January 2024

Introduction: Tuberculosis is one of the oldest and best-known diseases that has been with mankind for many years. Despite the reduction of infectious diseases in Iran, tuberculosis still remains in some parts of the country, especially in the south of Iran. The aim of this study was the epidemiological investigation of tuberculosis in Sistan and Baluchistan Province.
Methods: The current research was conducted cross-sectionally in 2022. The study population included all the patients with tuberculosis in Sistan and Baluchistan Province. Data were collected by census method and using standard checklist. Data analysis was done using SPSS v16 software and descriptive and analytical tests.
Results: In this study, the files of 5382 patients with tuberculosis in Sistan and Baluchistan Province were examined. 2489 patients (42.6%) were men. The most affected group were 2309 elderly people (39.5%) and 20 patients (0.34%) with HIV. The number of 4309 patients (73.8%) were suffering from pulmonary tuberculosis. There was a significant relationship between the elderly age group (P=0.04), female gender (P=0.02), non-Iranian nationality (P=0.02), and urban residences (P=0.03) with tuberculosis. However, no significant relationship was observed between marital status (P=0.06) and prison history (P=0.07).
Conclusion: The incidence of tuberculosis fluctuated during the five years, but the overall incidence has been decreasing. Considering that some factors such as age groups, gender and symptoms such as cough, weight loss and chest pain increase the chance of contracting the disease. Therefore, doctors of health centers can take an important step in reducing the incidence of tuberculosis with timely visits and regular monitoring of the treatment process of patients.
Protective Effects Of Vitis vinifera And Carica papaya Seed Extracts On Diclofenac-Alcohol Combination Induced Kidney Damage In Albino Rats
Authors: Dic-Ijiewere EO , Osadolor HB , Bankole JK , Bini N , Idehen IC
Published: January 2024

Diclofenac is a non-steroidal anti-inflammatory drug commonly used in the treatment of pain and inflammatory conditions in the tropics. Its easy accessibility without prescription has made it a commonly abused medication. The abuse has recently become worrisome as young adults in Nigeria have been observed to concomitantly use diclofenac and alcohol for non-medical purpose. This study was undertaken to study the nephrotoxic effect associated with the combine use of alcohol and diclofenac using animal model, and the protective effect of Vitis vinifera (Grape) seed and Carica papaya (pawpaw) seed. Adult albino rats were divided randomly into groups of six rats each, and each group treated for 90 days with 5% or 45% alcohol with 2mg/kg diclofenac or 10mg/kg diclofenac, and some rats treated with grape seed and/or pawpaw seed concomitantly. Diclofenac and 45% alcohol combination induced nephrotoxicity in rats and oxidative stress characterised by elevated serum urea and creatinine, increased malondialdehyde and decrease in reduced glutathione, catalase and superoxide dismutase in kidney homogenate, as well as moderate interstitial congestion and haemorrhage in rat kidney histology section stained with Haematoxylin and Eosin, which was significantly ameliorated by the grape seed and pawpaw seed. There was a 1.32% increase in relative kidney weight in comparison with control rats. The severity of the nephrotoxicity observed with diclofenac-alcohol combination makes it a very unsafe practice. There is need to explore the nephroprotective benefits of Vitis vinifera seed and Carica papaya seed for maximum benefit to man.
Pola Komunikasi Organisasi Himpunan Mahasiswa Islam Cabang Palembang Dalam Membangun Loyalitas Anggota
Authors: Budi Mulia Jasa , Maharani Dwi
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pola komunikasi organisasi himpunan mahasiswa islam cabang palembang dalam membangun loyalitas anggota. Penelitian ini menggunakan metode penelitian deskriptif kualitatif. Teknik pengumpulan data dalam penelitian adalah menggunakan teknik observasi, wawancara dan dokumentasi. Dalam penelitian kualitatif digunakan pola komunikasi meliputi pola roda, pola Y, pola rantai, pola bintang dan pola lingkaran serta pola komunikasi dari Atas ke Bawah. Hasil penelitian tentang mengetahui pola komunikasi organisasi himpunan mahasiswa islam cabang palembang dalam membangun loyalitas anggota adalah Loyalitas anggota Himpunan Mahasiswa Islam Cabang Palembang pada dasarnya sudah terbentuk. Loyalitas ini terbentuk oleh adanya rasa kesatuan, persahabatan, kebersamaan, rasa saling percaya, rasa saling membutuhkan dan saling membantu satu sama lain antar anggota yang dihasilkan dari adanya Pendidikan pelatihan umum dan Pendidikan Pelatihan Khusus.
Moderasi Beragama Melalui Penguatan Media Siber Aswaja LTN NU Temanggung Sebagai Kontra Radikalisme
Authors: Mubarok Najib , Azizah Farinka Nurrahmah
Published: January 2024

Tujuan penelitian ini adalah untuk mengembangkan nilai-nilai moderasi beragama melalui media siber Aswaja dan untuk menguji coba media siber Aswaja sebagai kontra radikalisme. Metode penelitian yang dipakai adalah Participatory Action Research (PAR). Instrumen pengumpulan data menggunakan Diskusi terarah (FGD), observasi, dan dokumentasi. Dalam penelitian ini disimpulkan media siber Aswaja di LTN NU Temanggung sangat lemah. Lemahnya media siber Aswaja dipengaruhi lima faktor yaitu: ideologisasi media, penentuan tema konten, kepercayaan, sustainability media, dan traffic konten yang rendah. Untuk mengatasi masalah yang ada dilakukan pelatihan konten, SEO, strategi marketing, dan jurnalistik. Selain itu dibuat media website aswajanesia.com sebagai ujicoba media siber Aswaja.
Penerapan Fungsi Manajemen pada Gerakan Dakwah di Pimpinan Daerah Muhammadiyah (PDM) Kota Medan
Authors: Tanjung Yudha Ferdiansyah , Ritonga Hasnun Jauhari
Published: January 2024

The function of da'wah management consists of 4 (four) functions, namely takhthith, thanzim, tawjih, and riqobah. Muhammadiyah has a da'wah movement that is carried out in accordance with the Muhammadiyah Regional Leadership (PDM) of Medan City which is one of the structural Muhammadiyah organizations appointed in accordance with the congress formed based on previous Muhammadiyah deliberations. The da'wah movements carried out by PDM Medan City are: a) da'wah bil lisan; b) da'wah bil hal; c) da'wah bi tadwin; d) da'wah bil hikmah. The application of the management function to the cultural da'wah movement carried out by the Muhammadiyah Regional Leadership of Medan City is applied by paying attention to the cultural da'wah approach. The management function refers to takhtith (da'wah planning) where Muhammadiyah previously conducted deliberations and then would lower the decision to carry out how to da'wah, thanzim (organizing da'wah) where this organization is adjusted to the existing organizational structure, tawjih (driving da'wah), namely the implementation of da'wah that has been decided or planned in deliberations then realized, finally riqobah (control and evaluation of da'wah), namely supervision carried out on da'wah is carried out so that there is no confusion in da'wah.
Pengaruh Word of Mouth dan Brand Image terhadap Keputusan Memilih Layanan Rumah Sakit Pendidikan Universitas Hasanuddin
Authors: Indriani Dian , Akbar Muhammad , Arianto Arianto
Published: January 2024

Rumah sakit saat ini menjadi fasilitas layanan kesehatan masyarakat yang tidak hanya berorientasi sosial namun juga aspek bisnis. Persaingan antar fasilitas layanan jasa kesehatan yang semakin ketat menuntut rumah sakit untuk memperhatikan faktor-faktor yang melatarbelakangi, mengarahkan serta mendorong keputusan pasien dalam memilih rumah sakit, diantaranya adalah komunikasi dari mulut ke mulut (WOM) dan brand image. Penelitian ini bertujuan untuk mengetahui pengaruh WOM dan brand image terhadap keputusan memilih layanan rawat jalan di Rumah Sakit Pendidikan Universitas Hasanuddin. Penelitian ini dilakukan dengan metode kuantitatif deskriptif. Pengambilan data dilakukan dengan menyebarkan kuisioner terhadap 201 responden. Teknik sampling yang digunakan adalah aksidental sampling, yaitu menyebarkan kuisioner kepada responden yang kebetulan ada atau tersedia di suatu tempat sesuai dengan konteks penelitian. Pengolahan data penelitian menggunakan aplikasi SPSS versi 25.0 Pengujian instrumen dilakukan dengan uji validitas dan uji reliabilitas. Pengujian data dilakukan dengan uji asumsi klasik. Analisis yang digunakan adalah analisis regresi berganda. Pengujian hipotesis dilakukan dengan uji t dan uji F. Hasil penelitian menyatakan bahwa terdapat pengaruh word of mouth dan brand image terhadap keputusan memilih layanan rawat jalan rumah sakit baik secara parsial maupun secara simultan, namun pengaruh variabel WOM dan brand image secara bersama-sama (simultan) hanya sebesar 33,8 %, atau dapat dikatakan memiliki pengaruh yang lemah.
La musa aprende a contar: apuntes para una aproximación al simbolismo numérico de la Ilíada
Authors: Gomes Pérez Jesús Francisco
Published: January 2024

En este artículo se establece el contexto y marco teórico necesarios para proponer un acercamiento analítico al uso de los números en la Ilíada desde el punto de vista simbólico, apartándonos de la tradición crítica del poema que considera al número como un recurso netamente cuantitativo. También se da cuenta aquí de dos distintas secuencias numéricas y de cómo su uso afectaría el curso de las acciones en la obra homérica.
El tránsito de la transitividad: de Prisciano a la lingüística moderna
Authors: González Gallardo María Fernanda , Jiménez Martínez María Isabel
Published: January 2024

En este trabajo se hace un recuento sobre la manera en que ha sido entendido el concepto de transitividad por la gramática tradicional y cómo lo entiende la lingüística actual, a la luz de las reflexiones de Prisciano, gramático del s. VI. El objetivo consiste en identificar con claridad las dos concepciones, a partir de las que el gramático entendía este fenómeno de la sintaxis, una estrecha (más simple y reducida) y una amplia (con un grado mayor de reflexión lingüística); y la forma en que una y otra han influido en la teoría gramatical hasta la actualidad.
Nervous system damage in breast cancer patients receiving chemotherapy
Authors: Karpov Sergey M. , Babenko Daria V. , Tambieva Hava K.-C. , Klimenko Anna I. , Vyshlova Irina A.
Published: January 2024

This article presents modern ideas about the problem of damage to the nervous system in patients with breast cancer receiving chemotherapy. Breast cancer is the most common cancer of women worldwide. To date, chemotherapy is increasingly used in treatment regimens. However, many chemotherapeutic drugs are potentially neurotoxic, which increases the risks of acute and delayed side effects, including damage to both the central and peripheral nervous systems in the form of cognitive impairment and post-chemotherapeutic polyneuropathy, which significantly worsen the quality of life of patients. Due to the increased survival rate of patients, knowledge of the potential neurotoxic effect of chemotherapeutic drugs and timely diagnosis of damage to the nervous system is of particular relevance.
Modern aspects of physiology of muscle contraction
Authors: Shkarin Vladimir V. , Perepelkin Andrey I. , Chepuryaeva Olga S.
Published: January 2024

A lot of works have been devoted to the physiology of muscle contraction. Since ancient times, scientists have been studying the physiological processes, structure, organization and function of the human body. After all, only by studying in detail the structure and normal physiology of a person, it is possible to separate the norm from pathology, learn to diagnose various functional pathologies and ways to restore function. Much attention is paid to the physiology of muscle contraction, since human life itself, activity, motor function is associated with the work of muscles. In different periods of the development of medicine, approaches to the study and ideas about muscle contraction, the work of human muscles were different. In our opinion, it is very promising to study the problems and features of the physiology of muscle contraction.
Pharmacogenetic predictors associated with reduced risk of secondary to enalapril cough
Authors: Sychev Ivan V. , Denisenko Natalia P. , Kachanova Anastasia A. , Lapshtaeva Anna V. , Abdullaev Sherzod P. , Goncharova Lyudmila N. , Mirzaev Karin B. , Sychev Dmitry A.
Published: January 2024

Currently, the wide prevalence of the development of secondary to ACEIs cough (3.8 to 48 % based on different findings) is one of the core causes of the dramatic impairment of the patients’ quality of life, followed by drug discontinuation. The study had the purpose of revealing the pharmacogenetic predictors associated with the reduced risk of the dry cough AEs secondary to ACEIs, in particular enalapril. The study involved 217 patients with the diagnosis of "essential arterial hypertension", who took enalapril. The patients were assigned to 2 groups: Group 1 (study group): 104 patients without secondary to enalapril adverse drug reactions; and Group 2 (control group): 113 patients with secondary to enalapril cough. All the patients underwent pharmacogenetic testing. The analysis of the distribution of frequencies of the polymorphisms rs4149056 of gene SLCO1B1, rs4459610 of gene ACE, rs1799722 of gene BDKRB2, and rs62151109 of gene CLASP1 has revealed no differences between the group without adverse drug reactions and that with secondary to enalapril dry cough. The study has revealed a statistically significant association between the absence of adverse drug reactions and the presence of the genotype AG of gene SLCO1B1 rs2306283, genotype GG of gene ABO rs8176746 and rs495828.
Study of regulation and adaptive capabilities of the cardiovascular system of young people with different levels of physical activity
Authors: Muzhichenko Margarita V. , Novikov Denis S. , Nadezhkina Elena Yu. , Marinina Maria G.
Published: January 2024

The study of HRV of students indicates that regardless of the level of physical activity, young men had a more favorable type of regulation of the heart and high adaptive capabilities of the body. In students with a high level of physical activity, these differences are less pronounced.
Structural and functional features of donor blood hemoglobin in the presence of doxycycline and mexidol
Authors: Baeva Elena S. , Artyukhov Elena S. , Kurkina Olga S.
Published: January 2024

The effect of mexidol, doxycycline hydrochloride and sodium nitrite solutions on human oxyhemoglobin molecules was studied by spectrophotometry. It is shown that the presence of modifiers in the incubation medium in combination and separately contributes to their specific affinity to the hemoglobin molecule, which is reflected in the change in the ratio of ligand forms of hemoprotein. A tendency to decrease the level of methemoglobin formation in samples containing doxycycline and mexidol was revealed. Preliminary incubation of hemoglobin solutions with antibiotics studied helps to reduce the oxidative effect of sodium nitrite against hemoprotein molecules. The data obtained confirm the concept of the presence of non-antibacterial effects of doxycycline.
Correlation analysis of clinical and laboratory markers in COVID-19 and acute cerebrovascular accident
Authors: Vedenin Yuri I. , Shatalova Olga V. , Shatalov Andrey A. , Oreshkin Andrey Yu. , Nazaruk Alexander S.
Published: January 2024

Coagulopathies developing with COVID-19 are a serious problem. Increased fibrinogen levels, activation of coagulation, a direct damaging effect of the virus on the endothelium, and increased interaction of the platelet with the vascular endothelium play an important role in the development of thrombotic complications and the occurrence of acute cerebral circulatory disorders. Case histories of COVID-19 patients and those with secondary CHF were analysed. Among the biochemical blood parameters in COVID-19, an increased level of D-dimer, which reflects the severity of the course of coronavirus infection, as well as CRP and ferritin were revealed more frequently.
Results: Among biochemical blood parameters in COVID-19, an increase in D-dimer level, which reflects the severity of the course of coronavirus infection, as well as CRP and ferritin, is more frequently detected. In correlation analysis, a positive correlation was observed between the level of ferritin, CRP and stage of CT as well as between the level of D-dimer and the number of platelets
The significance of an interdisciplinary approach in the treatment of chronic generalized periodontitis in patients with metabolic syndrome
Authors: Starikova Inna V. , Patrusheva Marina S. , Chaplieva Elena M. , Piterskaya Natalia V.
Published: January 2024

The mechanism of influence of metabolic syndrome on periodontal tissues is currently insufficiently studied, but it is known that this pathology has several biological effects that may be related to the pathogenesis of periodоntal diseases. According to a review of modern literature, the analysis of the causal relationship of periodontitis with somatic diseases is important in planning of periodontal treatment and prevention of periodontal diseases. Clinical features of dental diseases associated with somatic pathology significantly affect the quality of patient’s life. At the same time, periodontitis associated with chronic bacteremia and endotoxemia is an aggravating factor in patients with metabolic syndrome. An interdisciplinary, integrated approach to the treatment of dental pathology allows the doctor to avoid most complications during the treatment and achieve a long remission for both somatic and dental pathology.