bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors Influencing Clinical Follow‐Up for Individuals with a Personal History of Breast and/or Ovarian Cancer and Previous Uninformative BRCA1 and BRCA2 Testing
Authors: Chadwell Sarah E. , He Hua , Knapke Sara , Lewis Jaime , Sisson Rebecca , Hopper Jennifer
Published: March 2018

Genetic testing for inherited cancer risk has recently improved through the advent of multi‐gene panels and the addition of deletion and duplication analysis of the BRCA genes. The primary aim of this study was to determine which factors influence the intent of individuals with a personal history of breast and/or ovarian cancer and negative or uncertain BRCA1 and BRCA2 testing to return to a hereditary cancer program for additional genetic risk assessment, counseling, and testing. Surveys were sent to 1197 individuals and 257 were returned. Of those participants who were planning to return to clinic, most cited having family members who could benefit from the test result as the primary motivation to return. Many participants who were not planning to return to clinic cited the cost of testing as a barrier to return. Cost of testing and concerns about insurance coverage were the most commonly cited barriers for the group of participants who were undecided about returning to clinic. Results from this study may be used to guide re‐contact efforts by clinicians to increase patient uptake to return to clinic for up‐to‐date genetic risk assessment, counseling, and testing.
Talking Points: Women's Information Needs for Informed Decision‐Making About Noninvasive Prenatal Testing for Down Syndrome
Authors: Dane Aimée C. , Peterson Madelyn , Miller Yvette D.
Published: March 2018

Adequate knowledge is a vital component of informed decision‐making; however, we do not know what information women value when making decisions about noninvasive prenatal testing (NIPT). The current study aimed to identify women's information needs for decision‐making about NIPT as a first‐tier, non‐contingent test with out‐of‐pocket expense and, in turn, inform best practice by specifying the information that should be prioritized when providing pre‐test counseling to women in a time‐limited scenario or space‐limited decision support tool. We asked women (N = 242) in Australia to indicate the importance of knowing 24 information items when making a decision about NIPT and to choose two information items they would most value. Our findings suggest that women value having complete information when making decisions about NIPT. Information about the accuracy of NIPT and the pros and cons of NIPT compared to other screening and invasive tests were perceived to be most important. The findings of this study can be used to maximize the usefulness of time‐limited discussions or space‐limited decision support tools, but should not be routinely relied upon as a replacement for provision of full and tailored information when feasible.
Record of Leaf and Pollen cf. Sloanea (Elaeocarpaceae) from the Middle Siwalik of Darjeeling sub-Himalaya, India and its Palaeobiogeographic Implications
Authors: More Sandip , Rit Rajarshi , Khan Mahasin Ali , Paruya Dipak Kumar , Taral Suchana , Chakraborty Tapan , Bera Subir
Published: March 2018

Fossil leaf impressions and pollen grains comparable to modern Sloanea sp. of Elaeocarpaceae collected from the middle part of the Siwalik sediments (Geabdat Sandstone Formation; Pliocene) in Darjeeling foothills of eastern Himalaya are reported in the present communication. On the basis of macro morphological features, leaf remains are described as a new species Sloanea siwalika sp. nov. This is the first authentic record of the occurrence of leaf and pollen grains comparable to the genus Sloanea L. from the Cenozoic sediments of India and Asia as well. The recovery of this species and other earlier-described evergreen taxa from the same formation, suggests the existence of a tropical, warm and humid climatic conditions during the depositional period. The present study further suggests that after Pliocene the taxon might have shifted from Darjeeling Himalayan region to the adjoining southeast Asian land masses, due to possible climate change caused by post-Pliocene orogenic movement of the Himalaya.
Provenance and Palaeoweathering Attributes of Proterozoic Rock Formations from the Son Valley, Central India
Authors: Dubey R. K. , Shankar Ravi
Published: March 2018

The characteristics of source rocks and weathering of Palaeoproterozoic phyllitic rock of Mahakoshal Group and Mesoproterozoic shales and siliciclastics of Vindhyan Supergroup exposed in Son Valley, Central India have been investigated by analyzing their chemical compositions. The investigations pertaining to the relationship between major-elements were carried out along Parshoi, Chitrangi, and Markundi areas of Son valley, Central, India. The studied rock strata have been classified into three categories namely phyllitic rocks, shales and sandstone.

The A-CN-K ternary diagram, CIW, CIA, MIA, and ICV values indicate about the similar provenance or source rocks subjected to severe chemical weathering, under dry and hot-humid climates in a basic and acidic environment with changing lower to higher PCO2 of continental flora. Various geochemical discriminantts diagrams, elemental ratios suggest that rocks are derived from post-Archaean-Proterozoic igneous source. The igneous source was mainly granite with a minor contribution of granodioritic rock, in a passive margin setting. The sediments responsible for formation of shale and sandstones were most likely deposited in the interglacial period in between the Mesoproterozoic and Neoproterozoic glacial times. Compositionally the sandstones is distinctive of cratonic environments with their passive continental margin setting. However, the phyllities of Mahakoshal Group suggests their formation under lower weathering conditions in dry climatic conditions which were operating on more intermediate to basic igneous rocks with abundance of mafic minerals.
A Novel Classifier Based on Composite Hyper-cubes on Iterated Random Projections for Assessment of Landslide Susceptibility
Authors: Pham Binh Thai
Published: March 2018

In this paper, the main objective is to discover an application of a novel classifier based on Composite Hyper-cubes on Iterated Random Projections (CHIRP) for assessment of landslide susceptibility at the Uttarakhand Area (India). For this, 1295 historical landslides events and landslide affecting parameters were collected and used for creating training and testing datasets. Other benchmark models namely Logistic Regression (LR), RBF neural network (ANN-RBF), and Naïve Bayes (NB) were chosen for comparison. Analysis results indicate that the CHIRP is the best, followed by the LR, the ANN-RBF, and the NB, respectively. Overall, the CHIRP indicates as a promising and good alternative method that could be used to assess landslide susceptibility in other landslide prone areas.
A Comparison Study between Traditional and Finite Element Methods for Slope Stability Evaluations
Authors: Göktepe Fatih , Keskin Inan
Published: March 2018

Landslides are amongst the major disasters that have occurred in Karabük, Turkey. Due to the rapid increase in population movement to new habitats in urban areas, the need for engineering structures will increase. This condition has led to the construction of arts, cultural facilities and housing in insecure regions these days. The excavations to prepare the construction site, the external loads due to heavy structures and the changes in coverage of the earth surface are among the reasons for landslides in such areas. In this study, the landslides that occurred due to unsupported excavation for the construction of Karabük university stadium were analyzed using the three softwares like Plaxis, Geoslope and Slide. The study area is critical in terms of slope problems. Mass movement in the stadium occurred in high plasticity clay units containing sand and silt. For this reason, it is necessary to carry out detailed studies before the construction of engineering structures. The landslide considered in the study were analyzed using finite element (FE) analysis and slice method. These approaches are used for evaluating the stability of natural slope by considering a failure mechanism, which is known as the plastic limit condition. Regarding safety factors calculated using the different numerical solutions confirm that the results obtained are similar. In addition, the landslide area is close to the predicted simulation results.
Research of Cross-borehole Section Based on Seismic and Well-logging Data using the “AZERI” Software Package to Determine the Well-placement
Authors: Ahmadov Tofig , Dozorov Aleksandr V. , Zapevalov Vladimir N.
Published: March 2018

This paper is devoted to the study of a cross-borehole section based on seismic and well-logging data using the “AZERI” software package to determine the well-placement. The main objective was verification of the algorithm and the software on the currently active wells. Overall, the study was conducted on two wells, one of them is reference and the other is the projected well which enabled us to compare the two results.

There are several approaches to determine the pay zone heterogeneity in cross-borehole section using the seismic data. Despite various applications, currently there is no application of the filtration properties determination methodology of pay zones in cross-borehole section based on seismic data. Completely different approach to the solution of this problem is considered in this paper. Especially the study of reservoir porosity and permeability of pay zone, as well as the prediction of the producibility of cross-borehole section based on seismic and well-logging data. Thus, the necessary knowledge about porosity and permeability of pay intervals and their producibility is obtained, i.e. the quantitative estimation of the parameters mentioned above is derived.

As a result, the accuracy of the achieved results is closely linked to the exploration field’s seismic-geological conditions, depth and the level of seismic data processing as well as the level of similarity of two seismic traces that are picked near the reference and projected wells, not to mention the accuracy of the interpretation of log data.

In conclusion, the production well placement determination was carried out by PANGEA Company of Moscow. The selected position of well No.1867 is matching well with the geological results of PANGEA. Therefore, “AZERI” software, constructed based on the algorithms developed by authors, shows that the future well placement risks for the deep drilling are significantly reduced.
Is earnings management sensitive to discount rates?
Authors: Haga Jesper , Ittonen Kim , Tronnes Per C. , Wong Leon
Published: March 2018

We argue that managers’ choice to manage earnings depends on the trade-off in the present value of expected future net benefits associated with that choice. Specifically, we examine if discount rates are associated with the likelihood that managers engage in earnings management to meet or beat various earnings targets. We find that discount rates are positively associated with income-increasing earnings management. This means that managers increase both accrual-based and real earnings management when discount rates are higher. However, the economic magnitude of this association is relatively moderate.
Cognitive performance in adolescents with Delayed Sleep‐Wake Phase Disorder: Treatment effects and a comparison with good sleepers
Authors: Richardson C. , Micic G. , Cain N. , Bartel K. , Maddock B. , Gradisar M.
Published: March 2018

The present study aimed to investigate whether Australian adolescents with Delayed Sleep‐Wake Phase Disorder have impaired cognitive performance and whether chronobiological treatment for Delayed Sleep‐Wake Phase Disorder improves adolescents' sleep, daytime functioning and cognitive performance. Adolescents with Delayed Sleep‐Wake Phase Disorder (mean = 15.68 ± 2.1 y, 62% f) reported significantly later sleep timing (d = 1.03–1.45), less total sleep time (d = 0.82) and greater daytime sleepiness (d = 2.66), fatigue (d = 0.63) and impairment (d = 2.41), compared to good sleeping adolescents (mean = 15.9 ± 2.4 y, 75% f). However, there were no significant between‐group differences (all p > 0.05) in performance on the Operation Span (ηp2 = 0.043), Digit Span (forwards: ηp 2 = 0.002, backwards: ηp2 = 0.003), Letter Number Sequencing (ηp2 < 0.001) (working memory) and Digit‐Symbol Substitution Tasks (ηp2 = 0.010) (processing speed). Adolescents with Delayed Sleep‐Wake Phase Disorder went on to receive 3 weeks of light therapy. At 3 months post‐treatment, adolescents with Delayed Sleep‐Wake Phase Disorder reported significantly advanced sleep timing (d = 0.56–0.65), greater total sleep time (d = 0.52) and improved daytime sleepiness (d = 1.33), fatigue (d = 0.84) and impairment (d = 0.78). Performance on the Operation Span (d = 0.46), Letter Number Sequencing (d = 0.45) and Digit‐Symbol Substitution tasks (d = 0.57) also significantly improved.
Early pubertal timing and adult adjustment outcomes: Persistence, attenuation, or accentuation?
Authors: Senia Jennifer M. , Donnellan M. Brent , Neppl Tricia K.
Published: March 2018

Early pubertal timing is associated with internalizing and externalizing problems during adolescence. However, few studies explicitly test whether early puberty is especially problematic for those with pre‐existing problems (i.e., accentuation) and little is known about whether the negative correlates of early pubertal timing persist past young adulthood. We address these questions using longitudinal data from up to 451 participants in the Iowa Youth and Families project (e.g., Ge, Conger, & Elder, 1996, 2001). We replicated and extended previous results reported for this sample during adolescence (e.g., early maturing boys and girls reported more substance use) and found some evidence for accentuation in adolescence for psychological distress and substance use. However, correlations between early puberty and adult outcomes assessed up to two decades later were largely indistinguishable from zero including attenuation effects. These results suggest that any negative correlates of early pubertal timing are attenuated by the fourth decade of life.
The Sine-Gordon regime of the Landau–Lifshitz equation with a strong easy-plane anisotropy
Authors: de Laire André , Gravejat Philippe
Published: March 2018

It is well-known that the dynamics of biaxial ferromagnets with a strong easy-plane anisotropy is essentially governed by the Sine-Gordon equation. In this paper, we provide a rigorous justification to this observation. More precisely, we show the convergence of the solutions to the Landau–Lifshitz equation for biaxial ferromagnets towards the solutions to the Sine-Gordon equation in the regime of a strong easy-plane anisotropy. Moreover, we establish the sharpness of our convergence result.

This result holds for solutions to the Landau–Lifshitz equation in high order Sobolev spaces. We first provide an alternative proof for local well-posedness in this setting by introducing high order energy quantities with better symmetrization properties. We then derive the convergence from the consistency of the Landau–Lifshitz equation with the Sine-Gordon equation by using well-tailored energy estimates. As a by-product, we also obtain a further derivation of the free wave regime of the Landau–Lifshitz equation.
Allogeneic stem cell transplantation for relapsed primary central nervous system lymphoma
Authors: Atilla Erden , Sahin Ugur , Atilla Pinar Ataca , Merter Mustafa , Ozyurek Elif , Ceyhan Koray , Bozdag Sinem Civriz
Published: March 2018

Primary central nervous system lymphoma (PCNSL), has an aggressive course and in untreated patients median survival is limited to three months. For relapsed PCNSL, the treatment options are few and results are usually unsatisfactory. Allogeneic Hematopoietic Stem Cell Transplantation (allo-HCT) has been widely used for treatment of relapsed/refractory NHL patients. However there are limited data whether graft versus lymphoma effect can work in PCNSL patients. Here, we present a relapsed refractory PCNSL case treated by allo-HCT.
Brain‐derived neutrophic factor in adolescents smoking waterpipe: The Irbid TRY
Authors: Alomari Mahmoud A. , Al‐sheyab Nihaya A. , Khabour Omar F. , Alzoubi Karem H.
Published: March 2018

Background

Brain‐derived neutrophic factor (BDNF) and tobacco consumption can affect many body functions and health. However, the relationship of BDNF with waterpipe (Wp) smoking is unknown. Therefore, the current study examined the relationship between Wp smoking and BDNF in adolescents.

Methods

Self‐reported tobacco consumption and serum BDNF were determined in 195 waterpipe and 288 nonsmokers in 7th–10th grade students.

Results

Stepwise regression that included Wp smoking, gender, BMI, and location, showed that only Wp smoking (p < 0.0001) and gender (p < 0.0001) were related to serum BDNF. In addition, the ANCOVA found a main effect for Wp smoking (p < 0.0001) and gender (p < 0.0001) with lower BDNF in males smoking waterpipe.

Discussion

BDNF was diminished in adolescent Wp smokers, which might predispose adolescents for systematic adverse health and behavioral alterations. These results extend the negative health risks associated with cigarette smoking to that of water‐pipe tobacco smoking.
Diferença na degeneração articular de acordo com o tipo de esporte
Authors: Jorge Pedro Baches , Sprey Jan Willem Cerf , Runco Guilherme Morgado , Lima Marcos Vaz de , Severino Nilson Roberto , Santili Claudio
Published: March 2018

Objetivo Determinar se a degradação de colágeno tipo II é determinada pelo tipo de esporte. O telopeptídeo carboxiterminal do colágeno tipo II (CTX-II), biomarcador de soro de degradação de colágeno, foi medido em atletas de esportes diferentes e comparado aos controles correspondentes.

Métodos A amostra consistiu em 70 participantes do sexo feminino com idade entre 18 a 25 anos, das quais 15 eram membros de uma equipe de futebol, 10 de uma equipe de futebol de salão, 10 de uma equipe de handebol, 18 de uma equipe de voleibol, e 7 de uma equipe de natação. Foram incluídos no grupo de controle 9 indivíduos sedentários, pareados por idade e sexo. Uma amostra de sangue de 3 ml foi coletada de cada participante e analisada usando um ensaio imunossorvente ligado a enzima (ELISA, do inglês enzyme-linked immunosorbent assay).

Resultados Uma comparação das concentrações de CTX-II das praticantes de diferentes esportes em comparação com o grupo de controle apresentou os seguintes valores de p: voleibol (p = 0,21); futebol (p = 0,91); handebol (p = 0,13); futebol de salão (p = 0,02) e natação (p = 0,0015). Portanto, na população investigada, o futebol de salão apresentou o maior risco de degradação do colágeno tipo II, e, consequentemente, de degradação da cartilagem articular, enquanto a prática de natação foi um fator protetor para a cartilagem articular. Não foi observada diferença estatisticamente significativa no índice de massa corporal entre os grupos.

Conclusão As jogadoras de futebol de salão estão expostas a uma maior degradação articular, enquanto as nadadoras apresentam menor degradação da cartilagem em comparação com o grupo de controle na população estudada, o que sugere que o fortalecimento dos músculos periarticulares e o exercício aeróbico em ambientes de baixa carga têm um efeito positivo na cartilagem articular.
Early Proterozoic granitoids of the Olenek complex (northern Siberian craton): petrogenesis and geodynamic setting
Authors: Donskaya T.V. , Gladkochub D.P. , Mazukabzov A.M.
Published: March 2018

The paper deals with geological and geochemical studies of granitoids of the Olenek complex in the Olenek uplift of the basement of the northern Siberian craton. The age of these granitoids was earlier estimated at 2036 ± 11 Ma. The granitoids of the Olenek complex correspond in composition to high-alumina quartz diorites, granites, and leucogranites of the normal petrochemical series. According to geochemical and mineralogical characteristics, the quartz diorites can be assigned to granites of the transitional I–S type, and the granites and leucogranites, to S-type granites. The εNd(T) values in the granites of the Olenek complex vary from −0.2 to + 1.4, and the Nd model age is 2.4–2.5 Ga. The quartz diorite is characterized by εNd(T) = + 3.0 and a Nd model age T(DM) = 2.2 Ga. The geochemical characteristics of the granites and leucogranites indicate their formation through the melting of a source of graywacke composition, whereas the quartz diorites resulted, most likely, from the mixing of granitic and basaltic melts. The fact that the granitoids of the Olenek complex intruded the folded rocks of the Eekit Formation but stay virtually undeformed massive bodies suggests that they formed at the postdeformation stage of the regional evolution after the completion of the Paleoproterozoic orogenic events. The intrusion of granitoids marks the completion of the formation of the Early Proterozoic Eekit fold belt on the western (in the recent coordinates) margin of the Birekta terrane of the Olenek superterraine and the final formation of the superterrane structure. At the next stage of magmatism (1.98–1.96 Ga), best pronounced in the uplifts of the basement of the northern Siberian craton, all terranes forming the Anabar and Olenek superterranes assembled into a single structure.
Au–Cu–Ag mineralization in rodingites and nephritoids of the Agardag ultramafic massif (southern Tuva, Russia)
Authors: Palyanova G.A. , Murzin V.V. , Zhuravkova T.V. , Varlamov D.A.
Published: March 2018

Gold-bearing albite–amphibole–pyroxene rodingites of the Agardag ultramafic massif (southern Tuva, Russia) are confined to the E–W striking serpentinite crush zone. A zone of gold-bearing nephritoids is localized at the contact of rodingites with serpentinites. Optical and scanning electron microscopy, electron probe microanalysis, and fluorescent, chemical, ICP MS, and X-ray phase analyses were applied to study Au–Cu–Ag mineralization in the serpentinites, rodingites, and nephritoids. Copper sulfides, chalcocite and digenite, are present in the serpentinites, whereas gold and silver minerals are absent. Copper impurity is found in antigorite, Cr-spinel, and magnetite (up to 0.1–0.3 wt.%) as well as parkerite (up to 1.2 wt.%) and millerite (up to 7.9 wt.%). A wide variety of native gold and copper minerals has been identified in the rodingites: (1) cuproauride and tetra-auricupride free of or containing silver impurities (0.1 to 1.2 wt.%); (2) electrum of composition Ag0.50–0.49Au0.50–0.51 (650–660‰) intergrown with AuCu, sometimes as exsolution structures; (3) electrum of composition Ag0.70–0.64Au0.30–0.36 (440–510‰), with inclusions of AuCu and copper sulfides (geerite and yarrowite); (4) high-fineness gold (750–990‰) as veinlets in electrum; and (5) native copper. The composition of copper sulfides varies from chalcocite to covellite. Submicron inclusions of hessite Ag2Te were found in chalcocite. The amount of copper, gold, and silver minerals in the nephritoids is much less than that in the rodingites. The nephritoids contain chalcocite, electrum of composition Ag0.64–0.63Au0.36–0.37 (530–540‰), cuproauride, and tetra-auricupride. The detected hypergene minerals are auricuzite, apachite, brochantite, high-fineness gold, native copper, and cuprite. The sequence of mineral formation in the Agardag ore occurrence has been established on the basis of mineral structures and mineral relations in the rodingites and nephritoids. It is proved that Au–Cu–Ag mineralization formed with the participation of Au- and Ag-bearing chloride-free low-sulfur carbon dioxide alkaline fluids in reducing conditions.
Seismic stratigraphy of the Upper Quaternary deposits on the northeastern slope of the Ceará Rise (Central Atlantic)
Authors: Borisov D.G. , Murdmaa I.O.
Published: March 2018

This study is focused on interpretation of ultrahigh-resolution seismoacoustic data from the northeastern slope of the Ceará Rise (Central Atlantic) acquired using the SES 2000 deep parametric narrow-beam subbottom profiler during cruise 35 of RV Akademik Ioffe in 2011. The geologic nature of most of the detected reflectors is constrained by correlation of the results of seismoacoustic profiling with core data collected in frame of the Ocean Drilling Program (ODP site 929A-E). Detailed seismostratigraphic study of the Upper Quaternary deposits in the study area has implications for better understanding of the role of gravity flows and bottom currents in sedimentation on the NE slope of the rise for the past 1.2 Myr.
The Campanian–Maastrichtian magnetostratigraphy of the Volga region (vicinity of Volsk town)
Authors: Guzhikova A.A. , Ben’yamovskii V.N.
Published: March 2018

Paleomagnetism and rock magnetism have been studied for the first time in Campanian–Maastrichtian carbonate deposits (Sengilei, Karsun, and Radishchev Formations) from the Bolshevik and Kommunar quarries near the town of Volsk (Saratov area, Volga region). Characteristic components of normal and reverse polarity were detected in samples demagnetized in the alternating field, and positive results of the reversal test were obtained. The virtual geomagnetic pole wander paths calculated for the Sengilei Formation and lower Karsun Formation rocks showed statistical similarity to those for stable Europe of the respective age. The magnetostratigraphic zones revealed in the Bolshevik and Kommunar sections were correlated to chrons 33r, 32n2, 32n1, and 31r of the geomagnetic polarity time scale. The magnetic zones of predominantly reverse and normal polarity detected, though discontinuously, in the low magnetic uppermost Karsun Formation and in the Radishchev Formation correspond to the top of chron 31r and joint chrons 31n and 30n, respectively. Rock magnetic data help identifying deposits rich in cosmogenic metal particles and provide stratigraphic constraints on the Radishchev Formation base.
Distribution of organic matter in rocks of the Bazhenov horizon (West Siberia)
Authors: Kontorovich A.E. , Ponomareva E.V. , Burshtein L.M. , Glinskikh V.N. , Kim N.S. , Kostyreva E.A. , Pavlova M.A. , Rodchenko A.P. , Yan P.A.
Published: March 2018

We studied the distribution of organic carbon in rocks of the Bazhenov horizon, a unique object of predominantly biogenic sedimentation in the West Siberian sedimentary basin. The contents of organic carbon in the rocks were determined using the data from 4094 core analyses and core-log relationships derived from 48,500 radioactive- and electrical-log measurements. For the Bazhenov and Tutleima Formations, both approaches gave the same results. The average content of organic carbon in the rocks is 7.7%. These data were used to compile a detailed map of the distribution of organic carbon contents in sedimentary rocks of the basin. It was shown that the average organic carbon content in the rocks increases from 2–4% on the periphery of the basin to 10–12% in its central, deepest part. The distribution of Corg values in the basin is highly asymmetric. The highest Corg values are observed in the southwestern part of the basin interior, where beds with > 10% Corg range in thickness from 5 to 12–15 m. In sections, the highest Corg values are observed in their middle and upper parts, composed predominantly of silicites and mixtites enriched in biogenic silica.
From babbling to first words in Tashlhiyt language acquisition: longitudinal two-case studies
Authors: Lahrouchi Mohamed , Kern Sophie
Published: March 2018

Strong similarities observed between babbling and first words suggest a universal foundation of word production in children. The aim of this work was to evaluate the role of biomechanical constraints on babbling and first words production in two children acquiring Tashlhiyt, a Berber language spoken in Morocco. When considering isolated sounds and syllable types, our data provided evidence for a universal basis for early vocal patterns. The subjects produced more stops, more coronals and labials, vowels preferentially belonging to the lower left part of the vowel space, and open syllables. However, they only partially confirmed the existence of the preferred CV combinations generally observed in the early production of children learning various languages. The comparison between babbling and first words revealed a linguistic continuity between the two periods but also some increasing complexity and diversification in the words, which can be explained by an increase of articulatory capacities.
Social Capital and Mental Health in Post-Disaster/Conflict Contexts: A Systematic Review
Authors: Noel Pia , Cork Cliodhna , White Ross G.
Published: March 2018

Social capital (SC) is highlighted as an important factor for post-crisis mental health outcomes. However, the heterogeneous nature of the construct makes it difficult to get a clear picture of the evidence concerning the association between SC indices and mental health. This review examines how SC is conceptualized and measured, and the relationships with other variables in quantitative empirical studies investigating the associations between SC and mental health in post-disaster and post-conflict contexts. It includes primary data studies focusing on this association in civilian populations. Studies were identified by searching electronic databases, bibliographic mining, cited reference searching, and personal contact with experts. In total, 15 studies were included: 12 in post-natural disaster contexts and 3 in conflict-affected settings. Findings suggested that individual cognitive SC had an inverse association with post-traumatic stress disorder, anxiety, and depression, and that ecological cognitive SC was positively associated with mental well-being. Individual structural SC (in the form of community networks) may be psychologically protective. However, most of the evidence was cross-sectional, limiting conclusions about causal relationships. More clarity and consistency is needed in the conceptualization and measurement of SC in order to inform post-crisis mental health interventions. (Disaster Med Public Health Preparedness. 2018;12:791-802)
Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial
Authors: Rundblad Amanda , Holven Kirsten B. , Bruheim Inge , Myhrstad Mari C. , Ulven Stine M.
Published: March 2018

Marine n-3 (omega-3) fatty acids alter gene expression by regulating the activity of transcription factors. Krill oil is a source of marine n-3 fatty acids that has been shown to modulate gene expression in animal studies; however, the effect in humans is not known. Hence, we aimed to compare the effect of intake of krill oil, lean and fatty fish with a similar content of n-3 fatty acids, and high-oleic sunflower oil (HOSO) with added astaxanthin on the expression of genes involved in glucose and lipid metabolism and inflammation in peripheral blood mononuclear cells (PBMC) as well as circulating inflammatory markers. In an 8-week trial, healthy men and women aged 18–70 years with fasting TAG of 1·3–4·0 mmol/l were randomised to receive krill oil capsules (n 12), HOSO capsules (n 12) or lean and fatty fish (n 12). The weekly intakes of marine n-3 fatty acids from the interventions were 4654, 0 and 4103 mg, respectively. The mRNA expression of four genes, PPAR γ coactivator 1A (PPARGC1A), steaoryl-CoA desaturase (SCD), ATP binding cassette A1 (ABCA1) and cluster of differentiation 40 (CD40), were differently altered by the interventions. Furthermore, within-group analyses revealed that krill oil down-regulated the mRNA expression of thirteen genes, including genes involved in glucose and cholesterol metabolism and β-oxidation. Fish altered the mRNA expression of four genes and HOSO down-regulated sixteen genes, including several inflammation-related genes. There were no differences between the groups in circulating inflammatory markers after the intervention. In conclusion, the intake of krill oil and HOSO with added astaxanthin alter the PBMC mRNA expression of more genes than the intake of fish.
Meteorological factors and respiratory syncytial virus seasonality in subtropical Australia
Authors: Morley C. , Grimwood K. , Maloney S. , Ware R. S.
Published: March 2018

Evidence is emerging regarding the influence of meteorological factors on seasonal respiratory syncytial virus outbreaks. Data however, are limited for subtropical regions, especially in the southern hemisphere. We examined whether meteorological data (daily minimum and maximum temperatures, rainfall, relative humidity, dew point, daily global solar exposure) and tourist numbers were associated with the incidence of RSV in children aged <5 years for the Gold Coast region of South-East Queensland, Australia (latitude 28.0°S). RSV cases between 1 July 2007 and 30 June 2016 were identified from the Pathology Queensland Gold Coast Laboratory database. Time-series methods were used to identify seasonal patterns. RSV activity peaked in mid-to-late autumn (April–May), tapering in winter (June–August). While most meteorological variables measured were associated with RSV incidence, rainfall (ρ = 0.40, 95% confidence interval (CI) 0.32–0.48) and humidity (ρ = 0.38, 95% CI 0.29–0.46) 8 weeks earlier had the nearest temporal relationship. Tourist numbers were not correlated with RSV activity. Identifying meteorological conditions associated with seasonal RSV epidemics can improve understanding of virus transmission and assist planning for their impact upon the health sector, including timing of passive RSV immunoprophylaxis for high-risk infants and future public health interventions, such as maternal immunisation with RSV vaccines.
Dairy products and bone health: how strong is the scientific evidence?
Authors: van den Heuvel Ellen G. H. M. , Steijns Jan M. J. M.
Published: March 2018

The relevance of dairy produce for the diminishment of osteoporotic risk is still a matter of scientific debate due to the outcome of a few single observational studies. This review will address the most robust point estimate on the role of dairy products, as reported in systematic reviews and meta-analyses on randomised controlled trials in the case of bone mineralisation or prospective studies in the case of fracture risk. Plain dairy products or those fortified with Ca and/or vitamin D improve total body bone mineral content (BMC) by 45–50 g over 1 year when the daily baseline Ca intake is lower than 750 mg in Caucasians and Chinese girls. In Caucasian and Chinese women, Ca from (fortified) dairy products increases bone mineral density (BMD) by 0·7–1·8 % over 2 years dependent on the site of measurement. Despite the results on BMC, there are currently no studies that have investigated the potential of dairy products to reduce fracture risk in children. In adult Caucasian women, daily intake of 200–250 ml of milk is associated with a reduction in fracture risk of 5 % or higher. In conclusion, the role of dairy products for BMC or BMD has been sufficiently established in Chinese and Caucasian girls and women. In Caucasian women, drinking milk also reduces fracture risk. More research on the role of dairy products within the context of bone health-promoting diets is needed in specific ethnicities, other than Chinese and Caucasians, and in men.
Zeno breaking, the Contact effect and sensitive behaviour in piecewise-linear systems
Authors: EDWARDS R.
Published: March 2018

Non-smooth approximations of steep sigmoidal switching networks, such as those used as qualitative models of gene regulation, lead to analytic and computational challenges that arise as a result of the discontinuities in the vector fields. In order to highlight the need for care in dealing with such systems, several particular phenomena are presented here through illustrative examples, including ‘Zeno breaking’, or computing beyond the finite time convergence of an infinite sequence of threshold transitions; the ‘Contact’ effect, in which in the discontinuous limit, trajectories can pass through a ‘saddle point’ without stopping, though these solutions are not unique and other solutions stop for arbitrary time intervals; and sensitive behaviour that arises from exotic dynamics within switching regions.
Coca-Cola – a model of transparency in research partnerships? A network analysis of Coca-Cola’s research funding (2008–2016)
Authors: Serôdio Paulo M , McKee Martin , Stuckler David
Published: March 2018

Objective

To (i) evaluate the extent to which Coca-Cola’s ‘Transparency Lists’ of 218 researchers that it funds are comprehensive; (ii) map all scientific research acknowledging funding from Coca-Cola; (iii) identify those institutions, authors and research topics funded by Coca-Cola; and (iv) use Coca-Cola’s disclosure to gauge whether its funded researchers acknowledge the source of funding.

Design

Using Web of Science Core Collection database, we retrieved all studies declaring receipt of direct funding from the Coca-Cola brand, published between 2008 and 2016. Using conservative eligibility criteria, we iteratively removed studies and recreated Coca-Cola’s transparency lists using our data. We used network analysis and structural topic modelling to assess the structure, organization and thematic focus of Coca-Cola’s research enterprise, and string matching to evaluate the completeness of Coca-Cola’s transparency lists.

Results

Three hundred and eighty-nine articles, published in 169 different journals, and authored by 907 researchers, cite funding from The Coca-Cola Company. Of these, Coca-Cola acknowledges funding forty-two authors (<5 %). We observed that the funded research focuses mostly on nutrition and emphasizes the importance of physical activity and the concept of ‘energy balance’.

Conclusions

The Coca-Cola Company appears to have failed to declare a comprehensive list of its research activities. Further, several funded authors appear to have failed to declare receipt of funding. Most of Coca-Cola’s research support is directed towards physical activity and disregards the role of diet in obesity. Despite initiatives for greater transparency of research funding, the full scale of Coca-Cola’s involvement is still not known.
Carbon Release from Permafrost Erosion Along the Yukon Coast
Authors: Stanley Sarah
Published: March 2018

New findings highlight the need to account for large amounts of ground ice contained in frozen soil when assessing Arctic carbon cycling.
Modeling Global Change Ecology in a High–Carbon Dioxide World
Authors: Cheng Susan , Smith Nicholas , Marklein Alison
Published: March 2018

Ignite-style Session, Ecological Society of America Annual Meeting; Portland, Oregon, 11 August 2017
In vivodrug tracking with19F MRI at therapeutic dose
Authors: Bo Shaowei , Yuan Yaping , Chen Yongping , Yang Zhigang , Chen Shizhen , Zhou Xin , Jiang Zhong-Xing
Published: March 2018

A fluorinated amphiphile facilitates the sensitive19F MRI tracking of doxorubicin at its therapeutic dose through the construction of fluorinated liposomal drug delivery systems.
Solvent-dependent structural dynamics of an azido-platinum complex revealed by linear and nonlinear infrared spectroscopy
Authors: He Xuemei , Xu Fengmin , Yu Pengyun , Wu Yanzhou , Wang Fuyi , Zhao Yao , Wang Jianping
Published: March 2018

The ligand structural dynamics and solvent responses of a potential anticancer drug are revealed by ultrafast nonlinear infrared spectroscopy.
Crosstalk of the structural and zinc buffering properties of mammalian metallothionein-2
Authors: Drozd Agnieszka , Wojewska Dominika , Peris-Díaz Manuel David , Jakimowicz Piotr , Krężel Artur
Published: March 2018

Structural insights into partially Zn(ii)-depleted MT2 species and their zinc buffering properties are presented and discussed.
Methotrexate-conjugated mPEG–PCL copolymers: a novel approach for dual triggered drug delivery
Authors: Rostamizadeh Kobra , Manafi Mostafa , Nosrati Hamed , Kheiri Manjili Hamidreza , Danafar Hossein
Published: March 2018

A conjugate of the antitumor drug, methotrexate (MTX), with a diblock methoxypoly(ethylene glycol)–poly(caprolactone) (mPEG–PCL) copolymer was synthesized by the reaction of the mPEG–PCL copolymer with MTX in the presence of dicyclohexylcarbodiimide and dimethylaminopyridine.
How graphene crosses a grain boundary on the catalyst surface during chemical vapour deposition growth
Authors: Dong Jichen , Zhang Leining , Zhang Kaili , Ding Feng
Published: March 2018

The mechanism of graphene growth across the grain boundary of transition metal substrates during chemical vapour deposition processes is revealed.
High-performing ultrafast transparent photodetector governed by the pyro–phototronic effect
Authors: Kumar Mohit , Patel Malkeshkumar , Nguyen Thanh Tai , Kim Joondong , Yi Junsin
Published: March 2018

A visible transparent pyro–phototronic photodetector, which provides remarkable enhancements in the photo-induced current (121%), responsivity and detectivity (750%) and ultrahigh response speed of 4 μs under 365 nm at 4 mW cm−2.
Enhanced photoconductivity in CdS/betanin composite nanostructures
Authors: Susha N. , Nandakumar K. , Nair Swapna S.
Published: March 2018

The synthesis is described of inorganic/organic hybrid nanostructured composites based on CdS/betanin with enhanced photoconductivity due to the transfer of photogenerated electrons from the conduction band of betanin to the conduction band of CdS.
Thermo-economic analysis and multi-objective optimisation of lignocellulosic biomass conversion to Fischer–Tropsch fuels
Authors: Peduzzi Emanuela , Boissonnet Guillaume , Haarlemmer Geert , Maréchal François
Published: March 2018

Lignocellulosic biomass conversion to FT fuels: process configurations, optimization and thermo-economic analysis.
A highly selective “turn-on” fluorescent sensor for zinc ion based on a cinnamyl pyrazoline derivative and its imaging in live cells
Authors: Yang Yun-Shang , Ma Chun-Mei , Zhang Ying-Peng , Xue Qing-Hua , Ru Jia-Xi , Liu Xiao-Yu , Guo Hui-Chen
Published: March 2018

A fluorescence probe based on cinnamyl pyrazoline was developed and synthesized.
Polymer micro/nanocarrier-assisted synergistic chemohormonal therapy for prostate cancer
Authors: He Liang , Xu Weiguo , Wang Xiaoqing , Wang Chunxi , Ding Jianxun , Chen Xuesi
Published: March 2018

Polymer micro/nanocarrier-assisted chemohormonal therapy upregulates chemotherapy efficacy and down-regulates hormone level, effectively inhibiting the progression of prostate cancer.
Fluidized bed reaction towards crystalline embedded amorphous Si anode with much enhanced cycling stability
Authors: Zhou Yu , Guo Huajun , Yan Guochun , Wang Zhixing , Li Xinhai , Yang Zhewei , Zheng Anxiong , Wang Jiexi
Published: March 2018

The fluidized bed reaction route was introduced for the first time to prepare amorphous–crystalline silicon anode materials with excellent cycle stabilities.
Three-dimensional iron(ii) porous coordination polymer exhibiting carbon dioxide-dependent spin crossover
Authors: Shin Jong Won , Jeong Ah Rim , Jeoung Sungeun , Moon Hoi Ri , Komatsumaru Yuki , Hayami Shinya , Moon Dohyun , Min Kil Sik
Published: March 2018

A three-dimensional iron(ii) porous coordination polymer has been observed spin crossover behaviours through the sorption of H2O and CO2, respectively.
In situ simultaneous profiling of phosphorylation and ubiquitination by single excitation-duplexed luminescence resonance energy transfer
Authors: Ma Fengjiao , Zhang Lei , Wong Bernardino J. Córdova , Lei Jianping
Published: March 2018

A dual LRET system is developed for the in situ simultaneous profiling of phosphorylation and ubiquitination on a specific protein upon 980 nm excitation.
Evaporation, diffusion and self-assembly at drying interfaces
Authors: Roger K. , Sparr E. , Wennerström H.
Published: March 2018

A general scaling law is obtained for gradient build-up induced by advection/diffusion transport in evaporating non-ideal aqueous solutions.
Intermolecular interactions between σ- and π-holes of bromopentafluorobenzene and pyridine: computational and experimental investigations
Authors: Yang Fang-Ling , Yang Xing , Wu Rui-Zhi , Yan Chao-Xian , Yang Fan , Ye Weichun , Zhang Liang-Wei , Zhou Pan-Pan
Published: March 2018

The σ- and π-holes of C6F5Br exhibiting positive electrostatic potentials make these sites favorably interact with the N atom and π ring of C5H5N with negative electrostatic potentials.
Quantum spin Hall effect in two-dimensional hydrogenated SnPb alloy films
Authors: Ren Miaojuan , Yuan Min , Chen Xinlian , Ji Weixiao , Li Ping , Li Feng
Published: March 2018

Using first-principles calculations, we studied the geometric and band structures of 20 possible configurations of buckled hydrogenated SnPb alloy (SnxPb8−xH8) films.
Perovskite–silicon tandem solar modules with optimised light harvesting
Authors: Jaysankar Manoj , Filipič Miha , Zielinski Bartosz , Schmager Raphael , Song Wenya , Qiu Weiming , Paetzold Ulrich W. , Aernouts Tom , Debucquoy Maarten , Gehlhaar Robert , Poortmans Jef
Published: March 2018

Demonstration of efficient, large-area scalable perovskite–silicon tandem solar modules with optimised light management.
Ligament size-dependent electrocatalytic activity of nanoporous Ag network for CO2 reduction
Authors: Yang Wanfeng , Ma Wensheng , Zhang Zhonghua , Zhao Chuan
Published: March 2018

Nanoporous Ag (ligament size: 21 nm) exhibits superior CO selectivity and activity, confirming strong ligament size effects on CO2 reduction.
Selective coordination of cyanate and thiocyanate in the end-on mode: synthesis, structures and properties of [NiII2L(μ1,1-NCO)]+and [NiII2L(μ1,1-NCS)]+(L2−= macrocyclic N6S2ligand)
Authors: Jeremies Alexander , Gruschinski Sina , Schmorl Sara , Severin Tobias , Kersting Berthold
Published: March 2018

The complex [Ni2L]2+exhibits a pre-organized binding pocket, whose walls direct the coordination of pseudohalide ionsviarepulsive CH⋯π interactions.
Study of water adsorption on graphene edges
Authors: Jiang Lijuan , Wang Jinlong , Liu Peng , Song Wei , He Bingling
Published: March 2018

Water adsorption on graphene edges was studied by field emission (FE) experiments and first principles simulation.
Thermal property improvement of polytetrafluoroethylene nanocomposites with graphene nanoplatelets
Authors: Cai Xinzhi , Jiang Zeyi , Zhang Xinru , Gao Ting , Yue Kai , Zhang Xinxin
Published: March 2018

Adding GNPs into PTFE can significantly improve the thermal properties of nanocomposites.
A preliminary study on the formation pathways of glycated phosphatidylethanolamine of food rich in phospholipid during the heat-processing
Authors: Lin Qingna , Han Lipeng , Liu Guoqin , Cheng Weiwei , Wang Liqing
Published: March 2018

The formation of food-derived glycated phosphatidylethanolamine (PE) in thermal process was investigated by designing a 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE)-glucose model system heated from 40 to 100 °C for 8 h.
Role of NH4 ions in successive phase transitions of perovskite type (NH4)2ZnX4 (X = Cl, Br) by 1H MAS NMR and 14N NMR
Authors: Lim Ae Ran
Published: March 2018

The 1H chemical shifts and the spin-lattice relaxation time, T1ρ, in the rotating frame of (NH4)2ZnX4 (X = Cl, Br) are observed in order to investigate local phenomena related to successive phase transitions.
Ultrasonically synthesized organic liquid-filled chitosan microcapsules: part 2: characterization using AFM (atomic force microscopy) and combined AFM–confocal laser scanning fluorescence microscopy
Authors: Mettu Srinivas , Ye Qianyu , Zhou Meifang , Dagastine Raymond , Ashokkumar Muthupandian
Published: March 2018

Atomic Force Microscopy (AFM) is used to measure the stiffness and Young's modulus of individual microcapsules that have a chitosan cross-linked shell encapsulating tetradecane.
Heteroatom (P, B, or S) incorporated NiFe-based nanocubes as efficient electrocatalysts for the oxygen evolution reaction
Authors: Xuan Cuijuan , Wang Jie , Xia Weiwei , Zhu Jing , Peng Zongkai , Xia Kedong , Xiao Weiping , Xin Huolin L. , Wang Deli
Published: March 2018

Different heteroatom incorporated NiFe-based nanocubes are synthesized with MOFs as precursors and exhibit enhanced OER activities.