bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação da percepção de Cirurgiões-Dentistas acerca de Fissuras labiopalatinas
Authors: Silveira Machado Boff Júlia , Caroline D’Agostini Joana , Da Rocha Vieira Rúbia , Conde Alexandre , Bozzetti Pigozzi Lucas , Paulus Marília , Cortina Bellan Mariá
Published: November 2023

Os portadores de fissura labiopalatina (FLP) requerem cuidados do nascimento à idade adulta, envolvendo uma série de procedimentos de alta complexidade. O objetivo deste estudo foi investigar a percepção dos Cirurgiões-Dentistas em relação às condutas clínicas adotadas no tratamento de pacientes portadores de fissuras labiopalatinas. Para a coleta de dados, foi utilizado um questionário, contendo 7 questões, disponibilizado através da plataforma Google Forms®. Após a leitura do TCLE e aceite do mesmo, os participantes responderam a pesquisa (n=60). Os dados obtidos foram tabulados e analisados de forma descritiva por meio de frequência absoluta e percentuais. Os resultados obtidos revelaram informações importantes sobre o perfil dos profissionais envolvidos no estudo. A maioria dos dentistas participantes (71,7%) possui alguma especialização e 51,7% dos profissionais se formaram nos últimos 5 anos. No que se refere ao atendimento de pacientes com necessidades especiais, 65% dos cirurgiões-dentistas já tiveram experiência com esse tipo de paciente. A maior parte dos entrevistados (63,3%) ainda não teve a oportunidade de atender pacientes portadores de fissuras labiopalatinas, embora 60% estejam dispostos a fazê-lo e 65% não teriam objeções em relação a esse tipo de atendimento. No entanto, 40% dos cirurgiões-dentistas encaminhariam pacientes com fissuras labiopalatinas para outro profissional ou centro especializado, e 35% demonstraram sentir medo ou receio ao atender pacientes com essa condição. Apenas 53,3% dos profissionais receberam informações sobre o tema durante a graduação. A capacitação dos profissionais e a revisão curricular são passos essenciais para assegurar um atendimento inclusivo e de qualidade aos pacientes com fissuras labiopalatinas.
Experience of rehabilitation of the Shetland pony after femoral head resection
Authors:   St. Petersburg State University of Veterinary Medicine, St. Petersburg, Russia, Karklin Anastasiya I. , Korobchuk Maxim V. ,   St. Petersburg State University of Veterinary Medicine, St. Petersburg, Russia, Nechaev Andrey Yu. ,   St. Petersburg State University of Veterinary Medicine, St. Petersburg, Russia, Balashova Olga V. ,   Saint-Petersburg City Veterinary Station, Saint-Petersburg, Russia
Published: November 2023

The article proposes a methodology and a set of exercises and physiotherapy techniques, the use of which allows achieving good results in treatment and minimizing the manifestation of complications during the rehabilitation of a pony after resection of the femoral head. On the example of a clinical case in which the resection of the femoral head was the result of the impossibility of reducing the dislocation of the hip joint by conservative methods, the importance of a consistent, comprehensive and systematic approach to the postoperative recovery of the animal was demonstrated. The pony was followed up over a long period of time (more than 3 years) in order to assess both the short-term and long-term effects of treatment. In conclusion, the article concludes that the developed rehabilitation program is clinically effective and can be recommended for use in cases of postoperative recovery of medium-sized horses and ponies after resection of the femoral head.
The experience of using the domestic vitamin and mineral complex and its effect on the biological value of the products of slaughter of broiler chickens
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Abramov Pavel N. , Petrova Yulia V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Belova Nastasya K. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: November 2023

The article considers the issue of increasing the biological usefulness of the products of slaughter of broiler chickens when using domestic feed additives in the diet. It has been established that the vitamin and mineral complex «Productive® Forte» has a positive effect on the dynamics of the live weight of broiler chickens, while the mass of edible parts increases. We noted a higher protein content in the pectoral and femoral muscles of broiler chickens, as well as an increase in the content of polyunsaturated fatty acids. The vitamin content in the liver of broiler chickens of the experimental group significantly exceeds the control.
Prognostic value of neutrophil granulocyte MCV in cats with panleukopenia
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Pimenov Nikolay V. , Marzanova Saida N. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Permyakova Kristina Yu. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: November 2023

The article is devoted to feline panleukopenia. The studies involved 30 clinically healthy and 30 patients with panleukopenia. The morphological composition of the blood showed that the erythrocyte sedimentation rate (mm/hour) in patients was on average 3,3 times higher than in healthy animals (p<0,001). The number of erythrocytes in sick individuals exceeded healthy ones (p<0,05). A significant difference was noted in band neutrophils; patients had more of them than healthy ones (p<0,05). The difference between the average indicators of the groups was 5,5 times. The number of eosinophils in the blood was normal, but the difference between the experimental and control groups was significant (p<0,05). We associate the situation with some intoxication of the body of sick animals. Blood creatinine in healthy individuals was 1,2 times higher than in patients (p<0,05). As for urea, its increase was noted in sick individuals, which was due to impaired renal function (p<0,01). The average value of MCV in experimental animals was 0,31±0,10, and in the group of healthy animals 1,42±0,04.
Effect of biologically active complex of products on rumen digestion of sheep
Authors:   Federal Research Center of Animal Husbandry – VIZ named after Academician L. K. Ernst (FITZ VIZ named after L. K. Ernst). Dubrovitsy village, Russia, Lakhonin Pavel D. , Vyuchnaya Polina S. ,   Federal Research Center of Animal Husbandry – VIZ named after Academician L. K. Ernst (FITZ VIZ named after L. K. Ernst). Dubrovitsy village, Russia
Published: November 2023

Modern technology in animal husbandry leads to a large functional load on the organism of farm animals, so the organization of biologically complete feeding is an important task. For ruminants, rumen digestion plays a significant role in digestion and assimilation of nutrients, and natural supplements can have a significant impact on the microbiome and digestive processes in the rumen. The aim of the study was to investigate the effect of biologically active complex products (BACP) on the processes of rumen digestion in sheep. The studies were conducted by the method of group-periods in the conditions of physiological yard and laboratories of FGBNU FITZ VIZ named after L. K. Ernst on sheep with chronic rumen fistulas at the age of 6 years (n=30). The duration of each period was 100 days: in control period animals received the basic diet (BD), in the experimental period – 1,4 g per head per day of BACP (BD+C) were added to BD. The main diet contained 0,4 kg of grass-forb hay and 80 kg of OK-13,2 sheep concentrates, with a total nutritive value of 1 MJ ME. The BACP consisted of taxifolin, arabinogalactan, spirulina, organic iodine, microbial protein and malt sprout filler. The supplement components have antioxidant, prebiotic, mycogenic and other valuable properties. Samples of rumen contents were taken at the end of the periods from animals 3 hour before and 3,7 hours after feeding. In experimental period after feeding, there was a tendency to increase the formation of volatile fatty acids (VFA) by 10,70 % compared to the control period, as well as an increase in the concentration of ammonia by 0,05 % (at p<54,7). Oxidation of rumen contents in BD+C both before and after feeding was lower than BD by 0,001 % (at p < 48,2) and 0,001 % (at p<19,12), respectively. The redox potential of rumen fluid had a negative (reducing) value in both control and experimental periods. The total number of microorganisms in rumen of BD+C animals before and after feeding was higher than BD by 25,3 % and 28,6 %, respectively; the number of Lactobacillus in the rumen of experimental period was higher by 100 % with a decrease in the number of pathogenic microorganisms. Addition of 100 g (per head per day) of BACP to the basic diet of sheep promotes more effective assimilation of basic diet, improves the quality of rumen microbiota.
Ecological biotechnology: problems and perspectives
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Smirnova Ekaterina A. , Pimenov Nikolay V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Ivannikova Regina F. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: November 2023

Every year the anthropogenic influence of industry on the biosphere is becoming larger. Depletion of natural resources has become a serious threat to the environment and humans. The desire to improve the quality of life by using the latest technology has contributed to the actualization of such a branch of science as ecological biotechnology. The definition of its goals and objectives, described in this article, reveals the problems associated with the implementation of various methods to improve the environment. In this connection, the prospects of development of biotechnology not only as an applied science, but also as a scientific field, inseparably connected with the protection of human and animal health are considered.
Penyuluhan dan Pembuatan Produk Lilin Aromaterapi Berbasis Minyak Jelantah Di Desa Sibang Kaja
Authors: Gusti Ayu Dewi Lestari  , Balqish Fathoum Medinna  , Jessica Sanchez Anggraini
Published: November 2023

Indonesia merupakan negara dengan tingkat konsumsi minyak goreng yang sangat tinggi dimana jumlah limbah minyak goreng bekas atau dikenal dengan minyak jelantah juga sangat tinggi di Indonesia. Umumnya limbah ini tidak dimanfaatkan secara maksimal sehingga mengakibatkan pencemaran lingkungan. Untuk menanggulangi masalah terkait dengan minyak goreng bekas tersebut, maka dilakukan usaha agar limbah ini tidak mencemari lingkungan. Salah satu pemanfaatan minyak jelantah yang dilakukan adalah pembuatan lilin aromaterapi dari basis minyak jelantah. Lilin aromaterapi adalah lilin yang dibuat dengan cara menambahkan pewangi dengan berbagai tujuan dan manfaat yang dapat digunakan sebagai penyegar ruangan dan untuk menenangkan diri. Penyuluhan dan pelatihan pembuatan lilin ini diikuti oleh anggota posyandu remaja di Desa Sibang Kaja Kecamatan Abiansemal. Peserta mengalami peningkatan pengetahuan setelah diberi penjelasan mengenai pembuatan produk lilin aromaterapi dengan nilai awal sebesar 77,2% dan nilai akhir sebesar 91,2%. Dari data tersebut menunjukkan selisih nilai pengetahuan rata-rata pretest dan postest peserta adalah sebesar 14%. Adanya selisih nilai ini menandakan adanya perbedaan antara pengetahuan di kalangan masyarakat sebelum adanya penyuluhan dan pembuatan lilin aromaterapi dan sesudah dilakukan kegiatan ini.
Poetics of Dreams and Basket Weaving in Greg Sarris’ Mabel McKay: Weaving the Dream
Authors: - Prof. Brajesh Sawhney
Published: November 2023

Mabel McKay, a renowned Pomo basket weaver and healer, left an indelible mark on Native American artistry, culture, and spirituality. Her life and work embody a profound connection between the poetics of dreams and the intricate art of basket weaving. This research article delves into McKay's life, analyzing the interplay between her dreams, spiritual beliefs, and the craftsmanship of basket weaving as depicted in "Weaving the Dream," her biography by Greg Sarris. It explores how McKay's dreams shaped her artistic expressions, examining the symbolism, cultural significance, and spiritual dimensions of her baskets.
Qualitative Study of the Cross-cultural Adaptation of Chinese Students in Philippines
Authors: - Yanfu Heng , - Felisse Marianne San Juan
Published: November 2023

The paper sought to understand the current situation and problems of cross-cultural adaptation of Chinese students and provide a reference basis for cross-cultural adaptation. From January 2023 to July 2023, 12 Chinese students in the Philippines were selected by purposive sampling method, and semi-structured interviews were conducted by descriptive nature research method, and the data were analyzed by using Colaizzi's seven-step analysis method to extract themes. Three themes were extracted: life adjustment problems, communicative adjustment problems, and psychological adjustment problems. Firstly, the problems of communicative adaptation of Chinese students are more prominent, especially language problems and cultural differences are the main factors that produce communicative adaptation problems; secondly, the problems of living adaptation are common, especially the problems of accommodation environment and living conditions are the most critical factors that affect living adaptation; finally, the problems of psychological adaptation are not negligible, and psychological adaptation problems are the most important factors that Chinese students tend to solve through internal adjustment. International students are more inclined to adjust their psychological adjustment problems through internal adjustment means and are less likely to share their psychological difficulties actively, and compared with other adjustment problems, psychological adjustment problems are often more easily diluted and neglected by international students. This paper provides a qualitative study on the intercultural adjustment of Chinese students to provide a reference for the study of international students' intercultural adjustment and to provide information and emotional support for Chinese international students to promote the level of international students' intercultural adjustment ability.
Women Empowerment: Identity of Women in Ancient India and Modern Indian Globalized Society
Authors: - Vandana Singh
Published: November 2023

India's history and culture have earned itself a unique place on the global orb. In the world's top ten, our nation excels in terms of culture, politics, economy, military might, and other areas. Even if there were attempts to ameliorate these circumstances in the nation following independence, these measures have been more intense recently. Given that women comprise 50% of the population, they should be given ample deliberation. Consequently, to empower the human resources of the society, efforts are being initiated to strengthen, empower, and develop their innate qualities. Dr. Ambedkar had once stated that understanding a society's women's status is crucial to understanding its advancement. Just how robust can a civilization get? The idea of women's empowerment has gained traction in recent years and is now a hotly debated subject in today's culture. Women have historically been disadvantaged and mistreated in countries like India, thus empowering them is now essential to societal advancement. Globalization has brought about a paradigm shift in the Indian women's identity, presenting them with new opportunities as well as challenges in the contemporary world. Women in ancient India had a distinct identity that was moulded by cultural customs, religious beliefs, and social conventions. The purpose of this paper is to examine women's identities in Ancient India and Globalised Modern Indian scenario, with emphatic emphasis on their rights, roles, and difficulties. Patriarchal core value is the persistent perception of women as second-class citizens.
Effect of Rolling at Moderate Temperature on Mechanical and Physical Behavior of the Light Weighted Composite Materials
Authors: - Saurabh Lamba , - Nikul Kumar , - Peeyush Chauhan
Published: November 2023

An application of the light weight martials play the significant role in the modern industries. Such materials along with the high strength to weight ratio and significant mechanical attributes utilized to fabricate the new generation materials for automobile industries. Al and its alloy have been utilized widely in the current automotive industries, especially addition of silicon in aluminium alloy provide significant improvement in Mechanical and physical properties.
In the current study Al-Si alloy has been utilized as a base material to prepare the composite materials along with graphite powder. Fabricated materials have been characterized and evaluate the effect of rolling at moderate temperature on mechanical and physical properties. It has been found that the composite's material hardness have significant with respect to rising thickness reduction. The density of the materials continuously increases with increasing the percentage of thickness reduction and porosity reduced.
DEVELOPMENT OF THERMAL UNMANNED AERIAL VEHICLE (UAV) SYSTEM FOR ENERGY EFFICIENCY IN BUILDINGS
Authors: Ismail Bogrekci, Pinar Demircioglu Ismail Bogrekci, Pinar Demircioglu
Published: November 2023

In the scope of this study, a system was developed for performing essential thermal measurements with the aim of support energy efficiency in industrial places and public dwellings and determining heat energy losses. The system was established through using unmanned aerial vehicle, thermal cameras with wireless and RGB communication. Primarily calibration tests were carried out for flight time of unmanned aerial vehicle, landing after the flight, accuracy of lift-off, balance tests, images taken from colored and thermal camera. Radiometric, thermal and geometric calibrations were fulfilled at the calibration stage. After the calibration stage, thermal measurements were performed and heat losses were determined. It was selected two buildings and a parking lot, then essential measurements were done. According to heat loss calculation published by Turkish Plumbing and Engineers Association, heat losses were calculated, heat loss values taken from thermal cameras were compared and verifications and optimization processes were carried out for the system.
Keywords: Colored camera, energy efficiency, heat loss, thermal camera, unmanned aerial vehicle.
ON THE CORRELATION BETWEEN THE OUT-OF-COURT MECHANISMS FOR RESOLVING COLLECTIVE LABOR DISPUTES UNDER THE SETTLEMENT OF COLLECTIVE LABOR DISPUTES ACT AND THE MEDIATION
Authors:   Institute for the State and the Law - Bulgarian Academy of Sciences, Alexandrov Andrey
Published: November 2023

The study draws a parallel between out-of-court mechanisms for resolving collective labor disputes regulated by the Settlement of Collective Labor Disputes Act and the mediation. Based on the outlined similarities between them, the thesis is argued that there are two parallel and overlapping mechanisms for settling these disputes. Therefore, there is an obvious need for the special Settlement of Collective Labor Disputes Act to clearly define which disputes can be resolved through the methods provided for in it, in particular labor arbitration, as well as to normatively determine the correlation between the procedures under the Settlement of Collective Labor Disputes Act and the Mediation Act. It is logical for legal entities and individuals to distrust the use of alternative dispute resolution mechanisms if they do not give them certainty that they will achieve a result like the judicial one.
АPPLICABILITY OF ONLINE MEDIATION IN CYBERCRIME CONFLICTS
Authors:   Varna Free University "Chernorizets Hrabar", Kovacheva Galina
Published: November 2023

Cybercrime is an unconventional social phenomenon, which has transnational character. This necessitates using of unconventional modes to resolve the emerging conflicts. Trough online mediation, the aimed individual preventive impact on cybercriminals and fair compensation for victims of cyber offences can be achieved.
DIFFERENCES IN THE INTRODUCTION OF MEDIATION IN PRESCHOOL, SCHOOL AND HIGHER EDUCATION
Authors:   Institute of Information and Communication Technologies in Bulgarian Academy of Sciences, Savova Lilyana
Published: November 2023

This report examines the differences in the introduction of mediation in preschool, school and higher education through an author's methodology for the application of mediation in the educational environment through the author's experience over the past 4 years. The conclusions form and raise as relevant and important the issue related to the significant social effect in the application of mediation in education - reducing aggression and conflict, due to the developed skills for effective communication, conflict management and negotiation.
Transformasi Kewirausahaan dalam Era QRIS: Dinamika dan Solusi Sistem Pembayaran Nirkontan dari Perspektif Pedagang
Authors: Yadi Agni Prajna , Hartanto Arif Dwi , Ayatillah Much Samsya , Wicaksono Feri Nanang
Published: November 2023

The objectives of this study are to examine how technology acceptance factors (perceived ease of use, perceived usefulness, perceived security, subjective norms, and perceived compatibility) influence the intention of business owners/managers to adopt QRIS. Convenience sampling method was used for this survey. Data from 160 respondents were collected through a structured questionnaire measured with a Likert scale ranging from 1-7. An online-based web survey was utilized to reach the target respondents. Data were processed with SmartPLS and statistically tested with Structural Equation Modeling (SEM). The results indicate that perceived usefulness is the most important predictor of the intention to use QRIS. Additionally, a reasonably good predictive performance of the model is found. This research contributes to a more holistic understanding of the adoption of QRIS payment systems and provides insights that companies/merchant can leverage through the use of this payment technology. Significant implications for the development and refinement of QRIS. Developing a research model regarding subjective norms, perceived compatibility, perceived security, perceived ease of use, and perceived usefulness, including their roles in using QRIS. Helps explain the direct and indirect relationships in QRIS usage.
Predicting Quality of life of Schizophrenia Patients
Authors: Insiyah Insiyah , Rohimah Yeni Tutu , Astuti Sri Lestari Dwi , Lestari Siti , Suyanto Suyanto , Sulistyowati Endang Caturini
Published: November 2023

Background: Previous studies on sociodemographic characteristics connected to quality of life in schizophrenia discovered inconsistent results. This study aims to analyze predicting factors of quality of life (QoL) of schizophrenia patients.
 Methods: A quantitative study included 153 respondents who were selected using random sampling at the State Psychiatric Hospital Surakarta. The research instruments were a questionnaire containing questions about demographics consisting of age, age at first experiencing schizophrenia, gender, education level, work status, marital status, frequency of treatment, duration of suffering from schizophrenia, insight, physical health problems and quality of life by using WHOQOL-BREF. The analyses used were Spearmen's rank (rho) and the Pearson Chi-Square    to analyze factors connected to QoL of schizophrenia patients and multiple logistic regression tests to analyze predictors of QoL of schizophrenia patients. This study was conducted in the State Psychiatric Hospital of Surakarta from September 2020 to March 2021.
 Results: There were 4 characteristics of sociodemographic that have a positive significant relationship with the overall quality of life of schizophrenia patient, namely work status (p = 0.000), marital status with p = 0.000, gender (p=0.032), and adherence to take medicine with p=0.015 (p <0.05). marital status and work status that influence the quality of life (p=0.000 and p=0.001).  Marital status and work status influence the quality of life (p=0.000 and p=0.001), the largest OR value obtained is 25.499.  It means that married patients have a 25.499 times chance of having a better quality of life controlled by work status.
 Conclusion: Marital status and work status are predictors of QoL of schizophrenia. In providing services to schizophrenic patients, health professional need to pay attention in assessing social demographics such as work status and marital status so that appropriate action can be taken with an approach to these aspects.
The North Kuril zone: "user composition" of the commercial resource – Pollock from 2015 to 2022
Authors: Lisienko Svetlana
Published: November 2023

The article presents the results of the analysis of the distribution of volumes (quotas) of pollock production (catch) between users for industrial, coastal fishing and quotas for investment purposes of fishing in the North Kuril fishing Zone from 2015 to 2022.
A Smart Campus Internet-of-Things (IoT) Model for Smart Classroom Conditioning Using a Hybridized Technique
Authors: Amiefamonyo B. F. , Anireh V.I.E. , Matthias D.
Published: November 2023

This research study presents Smart Campus (SC) Internet-of-Things (IoTs) enabled systems model that will support end-user and automatic functions for proper air conditioning of SC classrooms environment. It consists of a hybrid data learning predictor system using an emerging variant of Artificial Neural Network (ANN) called Neuronal Auditory Machine Intelligence (NeuroAMI) and a Linear Regressor (LR) of polynomial-order-of-1.The system was initially applied separately to the automated coordination of a smart bed in a laboratory sized classroom environment at a University Campus, and simulated using the high-level programming language – MATLAB, while end user interaction model was developed in the Java2ME programming language. Simulations results considering several trial runs showed that the ANN predictor generally performed better than the LR model with over 80% classification accuracy. While considering limited training data points, the LR predictor was found to be superior at one of the simulation trial runs. At 20% data point, the LR was activated while the NeuroAMI remains inactive, but above the 20% level, the NeuroAMI performed better. One advantage of this proposed hybrid system is the ability to deal with continuous data; exactly the same way human brains functions. This feat has not been possible in conventional ANN systems, especially in this area dealing with small data points.
Examination of The Causes of Realignment of Electricity Wayleaves in South-East Nigeria
Authors: Obineme Chinaza Henry , Egolum Charles Chukwunwike , Ogbuefi Joseph Ugochukwu
Published: November 2023

The research is a study of causes of realignment of electricity wayleaves in the south eastern part of Nigeria. The aim of the study is to examine the causes of realignment of electricity wayleaves in South-East, Nigeria with a view to enhance revocation and compensation process. The study identifies causes of realignment of electricity wayleaves in the south eastern part of Nigeria. The study covered Abia, Anambra, Ebonyi, Enugu and Imo state. The total population of this study is 4304 comprises of 465 Estate Surveyors and Valuers, 422 Revoking Authority staff comprises of ESV consultants of TCN for the revocation and compensation exercise and ESV employees of TCN, and 3,417 Affected Rights Holders. A sample of 1031 was drawn from the five states and questionnaires were administered for the collection of data. The analytical tools used are tables, frequencies and percentages. The statistical model adopted for the study is the mean ranking, Relative Importance Index, and Pearson product moment correlation coefficient. The result of the study showed that engineering factor is the major cause of realignment of power line. It also revealed that Short notice given to ARHs on realignment route, Reason of realignment not explained to ARHs and Delay payment of compensation that ranked first with (RII = 4.63) is the major challenges faced by the ARHs. and the exercise was perceived to cause disunity and disaffection among community. The study revealed also that there is no difference between causes of realignment before and after assessment. The research recommended formation of committee for serious monitoring of the exercise and as such the exercise will foment unity rather than disunity and disaffection among committee.
Medicina, miedo y pánico en la sociedad limeña durante la Gran Rebelión: carta de una partera aristócrata, 1781
Authors: Walker Charles , Fernández Gonzales Karina
Published: November 2023

Este artículo permite esbozar a través de la carta de un personaje femenino llamada Lucía, partera y aristócrata, el impacto de la rebelión de Túpac Amaru en la sociedad limeña. Sentimientos de miedo y pánico, vividos por la población de la Ciudad de Los Reyes, se podrán encontrar en las líneas escritas por dicha mujer, así como el concepto de los limeños sobre José Gabriel. La carta anuncia la presencia de grandes personajes y nos informa sobre el oficio de partera de su autora, tema interesante para futuras investigaciones en torno a la medicina.
Prosumers of Hybrid Entertainment-Educational Communication in a Media Convergence Environment
Authors: Hidayat Z
Published: November 2023

Communication technology is changing the way of interacting by combining face-to-face classroom and online meetings. The YouTube channel is an alternative learning center where participants can share educational content. Participants act as producers and consumers of all knowledge products and simple technology. This paper discusses the involvement and characteristics of producers-consumers (prosumers) in producing, distributing, and consuming entertainment-educational content on Social Network Sites (SNS), especially YouTube. This paper also discusses changes in the educational landscape from and for fellow participants in online media as a consequence of media convergence by promoting a hybrid-learning alternative education model that combines informal contexts and formal education. Systematic Literature Review (SLR) is used as a research method to analyze several dimensions related to entertainment education, such as student and teacher knowledge and skills, antecedents, hybrid-learning cycles, Bloom's level of taxonomy, enactment, and prosumer outcomes in a model. YouTube content for prosumers is an entertaining sharing of knowledge for a safer, healthier, and happier life. Specifically, prosumers make YouTube and other social media as online classroom channels for completing school and university assignments and as fun learning centers to achieve the best academic performance. The existence of prosumers in hybrid education refers to the Flipped model by considering Bloom's taxonomy as practice and reflection in the cycle. The highest level in Bloom's is "creating" after prosumers did "evaluating," "analyzing," "applying," "understanding," and "remembering" as the lower levels. The implications of this research reflects the importance of development of entertainment-education contents as an alternative educational channel.
Complexity, Diversity, Homogeneity and Topology Measures Re-Define Biological Tumor Aggressiveness as a Function of Intercellular Connectivity
Authors: Waliszewski Przemyslaw
Published: November 2023

Similarity between patterns of cellular self-organization in primary tumor and in its normal counterpart underlies the concept of biological tumor aggressiveness. That subjective parameter is supposed to correlate with both dynamics of local tumor growth and the risk of progression. Subjective evaluation during the microscopic examination is inaccurate. The co-application of fractal geometry and algebraic topology offers a novel perspective. A set of prostate carcinomas comprising all patterns of self-organization was classified according to complexity and entropy to investigate how complexity relates to topology of the patterns. Prostate carcinomas evolve from order to disorder along the increasing entropy as many physical dynamic complex systems do. Carcinomas can be classified into the classes of complexity equivalence according to both the values of the global fractal dimensions D0 or D1 and the Shannon entropy H. Topological measures, such as the bottleneck distance or the Wasserstein distance reveal different topology in very low- and low-aggressive prostate carcinomas (class C1, C2, C3) in comparison with high-aggressive carcinomas (class C6, C7). This is contingent on the appearance of infiltrating cancer cells. While the persistent homology entropy Hph remains similar in all classes, the persistent barcode entropy Hpb is significantly decreased in class C1 and increased in class C7 in comparison with the other ones. Patterns of self-organization can now be defined according to changes in intercellular connectivity by the set of complexity, diversity, homogeneity, and topology measures.
Regulation of AMP-Activated Protein Kinase (AMPK) Subunit Expression at the Transcriptional Level by the Neutral Amino Acid Transporter SNAT2
Authors: Tae Kun , Cho Sang Woo , Lee Ho Yeon , Cha Hyo Sun , Choi* Cheol Yong
Published: November 2023

AMP-Activated Protein Kinase (AMPK) is a key enzyme that maintains cellular energy homeostasis. AMPK promotes catabolic pathways and inhibits anabolic pathways under low-energy conditions, such as glucose deprivation. SLC38A2/SNAT2 is an amino acid transporter that imports a wide range of neutral amino acids, including glutamine and alanine. The expression of SNAT2 is down regulated in patients with metabolic diseases such as obesity, nonalcoholic steatohepatitis, and hepatocellular carcinoma. Here, we demonstrate that SNAT2 is required for LKB1-mediated activation of AMPK. Depletion of SNAT2 results in diminished activation of AMPK under conditions of glucose or serum starvation, while the induction of SNAT2 expression augments AMPK activation. SNAT2 overexpression-mediated induction of AMPK activation is abrogated by LKB1 depletion but not by CaMKK2 or TAK1 depletion. Interestingly, the mRNA levels of AMPKβ2 are comparably reduced by SNAT2 depletion, indicating regulation of AMPKβ2 at the transcriptional level. AMPKβ1 mRNA levels are also reduced to a lesser extent. Consistently, SNAT2 depletion leads to a marked reduction in AMPK-mediated autophagy induction, as evidenced by reduced conversion to LC3 II and LC3 puncta formation under nutrient-deprived conditions. Given that AMPK activation plays a pivotal role in nutrient sensing and the subsequent cellular response to low-energy levels and various stress conditions, we provide another level of regulatory mechanism for AMPK-mediated cellular energy homeostasis.
Cardiovascular Complications of SARS-CoV-2 (COVID-19) in Adults
Authors: Ravindranath Thyyar M
Published: November 2023

Severe Acute Respiratory Syndrome-2 (COVID-19) was a devastating worldwide pandemic which affected multiple organs, resulting in significant mortality and morbidity. A hallmark of COVID-19 is the ability to mutate and infect efficiently as well as to spread widely among various age groups with special focus on the elderly and those with comorbid conditions. The advent of mRNA vaccine in a short period of time helped to mitigate hospitalization and mortality. This article will focus on the cardiovascular complications of COVID-19 and the treatment options. Also, the phenomenon of long COVID is discussed.
What Does Garlic Smell Like?
Authors: Patocka Jiri , Havel Josef , Pena-Mendez Eladia Maria
Published: November 2023

Garlic (Allium sativum) is an old cultivated plant that has been used by man for millennia for its extraordinary taste and great healing power [1]. The earliest records of the use of garlic come from Egypt. The ancient Egyptians were well aware of its healing properties and ate garlic in large quantities. A Papyrus from 1600 BC depicts a strike by workers working on the construction of the pyramid, protesting that they were not given garlic. The well-known Ebers papyrus, a collection of medical prescriptions 3500 years old, mentions the use of garlic in many diagnoses such as heart weakness, headache, intestinal parasites, eczema, gynecological problems, etc. [2]. The ancient Greeks and Romans also highly valued garlic as a medicinal vegetable. They were convinced that garlic cures coughs and clears the lungs of phlegm and pus. Doctors in China and India consider garlic to be a versatile medicine, treating everything with it: from colds to "aging" [3]. Garlic was first subjected to scientific investigation by Louis Pasteur in the mid-19th century when he studied its bactericidal effects [4]. Since then, garlic has been the subject of constant interest for many researchers.
Ingestion of 70% Ethanol with Methylene Blue in a Novel Rubbing Alcohol Formulation
Authors: M* Dowe , D Eshwar , M Montero , J Napier , J Cevallos , JF Martin-Lazaro
Published: November 2023

Recreational use of sanitizing alcohols, like rubbing alcohol, is a topic every emergency and intensive care Physician should be familiar with. Overindulgence in these substances can lead to ethanol toxicity. However, it's crucial for clinicians to recognize that these products often contain various other chemicals with harmful effects, such as methylene blue. In our analysis of the components of one such product, we present a case report of a patient who experienced alcohol poisoning after consuming it. Fortunately, the patient fully recovered after a brief stay in the intensive care unit. Our conclusion is that the oral ingestion of methylene blue in this product didn't exhibit significant or concerning clinical features. Therefore, the approach to managing such cases should be supportive, akin to dealing with ethanol toxicity.
Scinтigraphy in Children with Urinary Tract Dilatation (Antenatally Detected Hydronephrosis)
Authors: Ajdinovic Boris , Radulovic Marija , Bazic-Dorovic Biljana
Published: November 2023

The causes of Antenatal Hydronephrosis/Urinary Tract Dilatation (ANH/UTD) vary from transient benign conditions-transit hydronephrosis, (resolves by birth or during infancy) to conditions that can significantly affect renal function. The outcome of depends on the underlying etiology, so it is very important to determine these causes. The definition and grading of ANH is based on the Anteroposterior Pelvic Diameter (APD) of the fetal renal pelvis. Antenatal management includes antenatal ultrasound monitoring, which is usually repeated every 4-6 weeks. It is recommended that the assessment of the severity of postnatal hydronephrosis is based on the APD of the renal pelvis. Extensive postnatal investigation was proposed to be limited to those with moderate or severe dilatation. Voiding cystourethrography and scintigraphy are usually preserved for children with postnatal APD <15 mm and/or abnormal kidney parenchyma, severe caliyx dilatation ureteral dilatation and bladder pathology. Diuretic renal scintigraphy is important in the postnatal evaluation of infants with ANH, particularly in distinguishing kidneys with poor drainage from nonobstructive hydronephrosis with good drainage. According to our diuretic renography results, we conclude that in the presence of partial or no drainage, the separate renal function may not be significantly impaired. The finding of poor renal emptying is significantly more common among children with increasing renal pelvis APD. Technetium 99m-dimercaptosuccinic acid renal scintigraphy (99mTc-DMSA) has been used in renal imaging to estimate the functional renal mass (damage to the kidney) and relative renal function, especially in pediatric patients. A statistically significant correlation between the degree of hydronephrosis (APD) and DMSA scan finding and between the degree of the VUR and DMSA scan finding was established. Other than VUR, CAKUT (pelvic ureteric junction obstruction, pyelon et ureter duplex, megaureter, posterior urethra valves) were not statistically correlated with pathological findings on the DMSA scan.
Diversity of Non-Influenza Respiratory Viruses Associated with Influenza-Like Illness during 2009 pre and pandemic periods in Sao Paulo, Brazil, a Historical Overview
Authors: Sousa Paulino Renato de , Borges da Silva Daniela Bernardes , de Oliveira Santos Katia Correa , Benega Margarete Aparecida , de Paiva* Terezinha Maria
Published: November 2023

Background and objective: During the 2009 influenza A (H1N1) pandemic, 60% of the respiratory specimens collected from patients under surveillance for influenza-like illness (ILI) in São Paulo, Brazil, tested negative for influenza A and B by Real-Time RT-PCR (RT-qPCR) assays. In this retrospective study, we identified the diversity of other respiratory viruses associated with ILI during the pandemic period and added the benefit of RT-qPCR for their detection. Methods: Five-hundred and forty-two influenza RT-qPCR negative respiratory specimens from ILI patients collected from Jan - Dec 2009, that also tested negative by a commercial Indirect Immuno Fluorescence (IIF) assay for the Respiratory Syncytial Virus (RSV), Parainfluenza (PIV) PIV1, PIV2, PIV 3 and Adenovirus (AdV) were retested by a panel of RT-qPCR assays for the other respiratory viruses, including RSV, Human Metapneumovirus (HMPV), PIV 1-4, AdV, Human Coronaviruses (HCoV) OC43, 229E, NL63 and HKU1, Rhinovirus (RV), Enterovirus (EV) and Human Bocavirus (HBoV). Results: Of the 542 negative specimens, 428 (78%) were positive by RT-qPCR for another respiratory virus: In descending order: RV (149, 27%); RSV (41, 8%); AdV (32, 6%); HMPV (29, 5%); PIV3 (19, 4%); PIV1 (3, 1%); HCoV-OC43 (9, 2%); HBoV (9, 2%); PIV4 (6, 1%); HCoV-HKU1 (6, 1%); EV (5, 1%); HCoV-229E 4 (4, 1%); HCoV-NL63 (3, 1%). Co-detections of two viruses (98, 18%) and three viruses (12, 2%) were common. Conclusion: This retrospective study revealed a high prevalence of respiratory viruses other than influenza associated with ILI during the pandemic period and highlights the superiority of RT-qPCR over IIF for ILI surveillance.
The Impact of COVID-19 Pandemic on Cardiovascular Diseases in Brazil
Authors: NL Lopes Gilberto Henrique , da Silva Joselene Beatriz S , Carvalho Ronian S , T Martins Marcos Vinicius , Rocha Santiago S , de Oliveira* Stefan V
Published: November 2023

Background: The novel coronavirus pandemic is an international public health emergency due to the high contagious potential of the virus on a global scale and, similarly to what happened globally, Brazilian authorities took measures to reduce its impact on the healthcare system, including social distancing. In this context of exhaustion of the system, it is worth questioning the situation of patients who need medical care for other diseases, such as the cardiovascular ones. Objectives: Describe the changes in the epidemiological profile of hospitalizations cardiovascular diseases during the COVID-19 pandemic in Brazil. Methods: Assessment of relative variations on the number of hospitalizations, associated average time, mortality rate and financial investments. Results: After the beginning of the pandemic, there was reduction of 21.46% in hospitalizations, more accentuated in females and in the Northern region, and increase of 14.14% in mortality, of greater significance in the Midwestern region. In younger ages, mortality and permanence time presented more accentuated positive variations. In elective admissions, growth in mortality and in hospital expenses were more significant. Conclusion: The pandemic impacted on cardiovascular diseases in a multifactorial way. The number of hospitalizations decreased, and the mortality rate increased, as efforts concentrated on moderate and severe cases. Therefore, there is a need for policies that minimize mid- and long-term impacts, as well as studies that investigate possible late complications of infections by the novel coronavirus.
Unveiling the Untapped Potential: Cystatin C Testing in Kidney Function Assessment
Authors: Spencer Sebastian , Desborough Robert
Published: November 2023

The burden of Chronic Kidney Disease (CKD) remains a growing public health problem. In 2019, the worldwide prevalence was estimated at 7.2 to 13.4%, with CKD incidence, prevalence, mortality and disability-adjusted life years having risen by at least 20% from 2007 through 2017 [1].
Regulatory Policies of Genome Editing Products around the World
Authors: Wang Ying , Mu Yong , Yan Liuhua , Tang Bo , Jiang* Fukun
Published: November 2023

Genome editing is one of the powerful tools that has been applied to the improvement of plants, animals and microorganisms, and human therapy. The regulation of genome editing products vary among nations. Here we summarize the legislation of genome editing in different nations to let people know how genome editing products have been regulated in different nations. Additionally, the departments responsible for genome editing regulation in each nation are provided in this review.
Assessment of the Microorganisms Isolated from Artificial Eyelash Users
Authors: KO Iyevhobu , IO Babatope , AI Airefetalor , LE Omolumen , BA Ken-Iyevhobu , BA Omolumen , PO Abaku , DI Oseni
Published: November 2023

Eyelashes are shed, like other types of hair, from the follicle. Each eyelash has its own growth cycle (anaphase) that lasts six to eight weeks so that most eyelashes are present to maintain their collective protective mechanisms. This project work is to identify the microorganisms isolated from eye lashes users of students in Ekpoma. Eyelashes of the students were swabbed with a sterile swab stick that was soaked with normal saline. The swab stick was immediately replaced in its casing and labeled appropriately. Each specimen was refrigerated at 4°C as soon as it was collected. The bacteria isolates are Staphylococcus aureus and Klebsiella spp while the fungi isolates were Rhizopus spp and Candida albicans. The percentage prevalence of organisms isolated from the study. Staphylococcus aureus 25 (36.2%), Klebsiella spp 14 (20.3%), Rhizopus spp 11 (15.98%) and Candida albicans 19 (27.8%). The Staph aureus in the study was sensitive to Erythromycin, Gentamycin, Ciprofloxacin and Norfloxacin while the other antibiotics were resistant. Eyelash fixing can seriously predispose patronizing females to eye injury. The eye is a very important but delicate organ of the body; therefore it needs to be well protected to maintain one’s sight. Eyelash fixing is inimical to the eyelid and could be detrimental to vision and therefore the obsession on eyelash extension should be curbed.
TDI Analysis as Predictor of Positive Perugini Score in HFpEF Patients with Restrictive Phenotype
Authors: P Candela , E Corrado , MCE Valerio , P Camarda , L Ajello , EV Castelluccio , V Mineo , E Rebulla
Published: November 2023

Cardiac amyloidosis is an important but underdiagnosed cause of heart failure with preserved ejection fraction (HFpEF). We analysed TDI doppler with echo to determine if there is a correlation with positive results in myocardial sPECT in 86 consecutive patients presenting with HFpEF and suggestive criteria for cardiac amyloidosis [1].