bluuebunny/crossref_metadata_2025 huggingface dataset:
The Perception of Therapists on the Effectiveness of CBT in Altering Mental Well-Being
Authors: Khatri Saajid , Dunn Emily
Published: April 2023

Cognitive behavioral therapy (CBT) has gained support over the past few years due to the more popularized perception of researchers and therapists for its ability to help patients suffering from mood disorders. Moreover, it is currently being used alongside a variety of techniques and other treatments. In the past, research has focused on the ability of CBT to mitigate physical symptoms, including fatigue and high heart rate, that emerge from mood disorders. In an attempt to fill in the gap by focusing on mental well-being as opposed to physical symptoms, this study aimed to establish how the perceptions of therapists showcase the effectiveness of CBT in altering the mental well-being of patients with mood disorders. In order to gain an in-depth understanding towards this concept, interviews were conducted with cognitive behavioral therapists in Indiana. Ultimately, this research led to 2 main conclusions: CBT and mental well-being are connected, and the extent to the effectiveness of CBT depends on the specific tools that are utilized. Specifically, when utilizing the CBT tools of testing logic and homework, mental well-being was seen to improve, while when utilizing the tools of confronting fears and enneagram tests, no effect was seen on mental well-being. Future research, however, must be conducted in order to further the idea of altering a patient’s mental well-being as it relates to different population samples and other forms of therapy.
Predicting Diabetic Retinopathy Using Machine Learning
Authors: Zhang Nathan
Published: April 2023

Over the last 3 decades, advances in laser surgery and intraocular drug delivery have decreased the risk of diabetic retinopathy. However, the use of artificial intelligence and other forms of data analysis in retinopathy screening has not had the same advances. This project aimed to analyze the National Health and Nutrition Examination Survey and to develop the best machine learning model to predict the disease. Violin plots were created to compare the distribution of diabetic retinopathy diagnosis with gender. The plot showed that females who had said they were not taking insulin were less likely to be diagnosed with diabetic retinopathy. Another violin plot showed that those with hypertension who were taking insulin were less likely to have diabetic retinopathy. Histograms were also created to show the distributions of the variables, color-coded by retinopathy diagnosis. Specifically, it was found that the bigger the time gaps since the diabetes diagnosis, the more likely a person suffers from diabetic retinopathy. Finally, multiple machine learning models were tested and these were the most accurate in predicting diabetic retinopathy with an 80% accuracy, LinearSVC, CalibratedClassifierCV, and Logistic Regression.
Development of DNMT Inhibitors for Breast Cancer Therapy Using In-Silico Methods of Drug Research
Authors: Suresh Neanth , Kovvali Omkar
Published: April 2023

DNA Methyltransferase activity has been linked to the proliferation of breast cancers. Based on this, inhibiting DNMTs would be a strong preventative measure for cancer, as well as a possible treatment. Synthesizing drugs that can impede DNMTs is time-consuming and expensive to do in vitro and in vivo, so molecular biologists are resorting to in-silico methods of drug development. In-silico methods have been used to study DNMT inhibition, such as with compounds like ISL and RG108, as well as with large sets of thousands of compounds, as it saves time and money.
The Most Significant Factor Responsible for COVID-19 Vaccine Hesitancy in England
Authors: Onyeaka Celina , Deu Pelvinder
Published: April 2023

Objectives: This research aims to evaluate the factors responsible for the acceptability and hesitancy of the COVID-19 vaccine in England by evaluating the public's willingness to get the vaccinations. This is cross-sectional population-based research where data were collected through a structured online survey.

Methods: From December 2021 to February 2022, a cross-sectional survey including English residents was carried out utilizing a structured online questionnaire. Participants' demographics and opinions on COVID-19 and the COVID-19 vaccination were surveyed.

Results: There were 320 participants, of which 286 people (89.7%) were from West Midlands region of England.     296 (92.5%) had received at least one dose of the COVID-19 vaccination with 127 of them  (43%) having taken at least 2 doses of the COVID 19 vaccine. 24 people (7.5%) had not yet taken the COVID-19 vaccine. 17.9% (53 people) of the 296 indicated that they were hesitant at first before taking the vaccination whilst 82.1%(243 people) said they had confidence in the COVID-19 vaccination. The main reason given by 208 people (70.1%) for taking the vaccine was to protect others and themselves. Altogether  75 out of 320 people (23.4%) felt hesitant about taking the COVID-19 Vaccine. The most indicated reason for this by 47 people (62.7%) was a lack of trust in the safety and effectiveness of the vaccines. 193 respondents (79.8%) indicated they were happy with their decision.

Conclusion: The COVID-19 vaccine has been administered to a significant majority of the study participants. However, this study has shown that lack of trust in the safety and effectiveness of the vaccines is the most indicated reason for COVID-19 vaccine hesitancy and therefore further awareness-raising actions may still be needed from the government, public health professionals, and advocacy organizations in order to persuade more people to adopt the COVID-19 vaccination.
The Naked Shorting on ETFs in the Modern Economy
Authors: Chinchar Allison , Romansky Kyle
Published: April 2023

Executionary naked shorting, or cellar boxing, is a form of manipulation found within the stock market. To combat naked shorting, the SEC adopted Regulation SHO. Regulation SHO also includes the threshold list which publishes the securities that have an excessive amount of fails. Exchange-traded funds are relatively new securities that trade like stocks. Richard Evans, University of Virginia, (2019) found that around 1% of ETFs are failing at any given time. Additionally, many ETFs are always found on the threshold list. This study analyzes the effects naked shorting has on ETF behavior during a recessionary and calm period. A data analysis was performed on the Regulation SHO threshold list appearances and the French-Fama-Carhart 4 Factor Model was used on the ETFs with the most severe naked shorting cases. The ETF market was affected by the recession, but I found that it recovered very quickly. Additionally, the FFC 4 Factor model revealed that momentum was neither negative nor significant, indicating that cellar boxing does not take place in the modern ETF market. The FFC 4 Factor model also revealed that the only consistently significant factor was the market risk premium, indicating that ETFs fail simply because of the market conditions. I show how executionary naked shorting is not pervasive in the modern ETF market.
A Study on The Effect of Big Data Analytics on Product Innovation Performance
Authors: Cheng Chih-Hsuan Ashley , Hong Millie Y.S. , Cheng Colin C. J.
Published: April 2023

Despite the rising interests in the use of big data analytics (BDA), it is unclear whether the use of BDA is beneficial to product innovation. Building on the Resource-Based View, this study aims to examine the relationship between BDA and product innovation performance. Conducting survey from 163 firms, this study provides compelling evidence indicating that the use of BDA has a significant positive impact on firms’ product innovation. This study discusses theoretical implications for advancing BDA research and suggests actionable steps for managers to get benefits from using BDA.
Effects of Salinity on Clay Flocculation in the Context of Mitigating Karenia Brevis Blooms in the Tampa Bay
Authors: Tucker Stella , Orrego Jamela
Published: April 2023

Objective: Tampa Bay Area is an estuary and thus has varying levels of salinity, so it has become imperative to determine whether or not the leading combat strategy (clay flocculation) to HABs is effective under these differing conditions. Method: an experiment was conducted that measured the settling rates of Kaolin clay at varying levels of salinity (0, 17.5, 30, and 45 Parts Per Thousand) within the range of Karenia Brevis. Results: There is no statistically significant difference between the settling rates of Kaolin clay within the range of tolerance of K. Brevis, and therefore can be used to combat K. Brevis blooms in Tampa Bay regardless of salinity.
Nursing Homes:The Overshadowed and Undervalued Aspects of Covid-19 By:Abdul Hadi Kamran
Authors: Kamran Abdul Hadi , Aguilar Angel
Published: April 2023

Abstract

Every 100 years, some sort of infectious disease devastates the world.  In 1720, we had the Plague, in 1817, Cholera, in 1918, the Spanish Flu, and now in 2020, we have the Coronavirus.  The disease, having been first discovered in Wuhan, China, soon took the world by storm as more and more people fell ill to the contagious disease.  Due to how new and unique the disease was, everyone was vulnerable to it.  However, certain demographics were at a higher risk of being fatally affected by the disease.  This being the elderly and young children.  At the start of the pandemic, the entire world was focused on hospitals, how to quarantine patients, where to separately keep them, etc.  The type of facility with the highest percentage or the elderly, however, are not in fact hospitals.  The type of facility with the highest percentage of elderly is Nursing Homes, who were treated extremely differently to hospitals during the early portion of the pandemic.  The goals of this project were to assess the mentality of those who were held responsible for the lives of those most at risk, and whether or not they believe they were given adequate support during the pandemic.
The Gut Microbiome and Alzheimer’s Disease: Can the Gut be Used to Prevent or Treat Dementia?
Authors: Vundi Samhitha , Chatila Zena
Published: April 2023

Alzheimer’s disease (AD) is a neurodegenerative disease and the most common cause of dementia1. There are currently no effective therapies for AD and its etiology remains poorly understood. Recent research has suggested that the gut microbiome may modulate risk for AD, as well as the disease process itself. This paper reviews the current knowledge surrounding AD and the gut microbiome, and aims to explore how this relationship may be used to advance our clinical understanding of the disease; including whether the gut microbiome could be a novel drug target or even serve as a potential biomarker for AD. Although this relationship between AD and the microbiome has not yet been fully elucidated, the gut microbiome is known to dynamically respond to lifestyle factors including sleep, exercise, and nutrition, all of which impact AD-risk. This body of evidence suggests that there may be a relationship between microbiome health and AD. Early studies are investigating whether the microbiome is changed in individuals with AD, and whether any metabolites or bacterial signatures unique in AD populations could be used as a biomarker for early detection of the disease. This review will discuss these points and reflect on how the clinical landscape for AD may be improved by assaying the microbiome and implementing lifestyle factors that both improve microbiome health and reduce AD risk.
High School Students’ Psychological Distances to Climate Change in Rural Southern Maryland
Authors: Allred Adrianne , Solomon Robin
Published: April 2023

With the academic consensus thoroughly agreeing that climate change is anthropogenic, research is examining the public’s perceptions of climate change through the psychological distance framework to ultimately develop climate change prevention strategies. Researchers generally agree that psychological proximity predicts climate concern, and concern predicts action. To fill the gap in the research surrounding youth perceptions of climate change, this study investigates students’ psychological distance to climate change in a rural southern Maryland high school. Analysis of participants’ open-ended and closed-ended responses suggest that youth who have been exposed to firsthand climate change-associated events and impacts tend to have proximal perceptions of climate change and high climate concern. This research supports direct and interactive exposure to impacted ecosystems to proximize climate change, influence climate concern, and ultimately encourage action. Future research should investigate youths’ perceptions in developing countries and other climate sensitive locations, as well as using experimental approaches to further investigate the relationship between psychological distance, concern, and action in youth populations.
Exploring the connections between alcohol and chronic traumatic encephalopathy
Authors: Srivastava Arnav , Kethar Jothsna
Published: April 2023

In the world of hard-hitting sports, a deadly consequence has come up in the past years: chronic traumatic encephalopathy (commonly known as CTE). This brain condition has long eluded scientists attempting to find a treatment and the effects of it are some of the worst we have ever seen. Moreover, the appearance of the disease has only increased in occurrence over recent years. Football, hockey, and other physical sports continue to get more and more popular across the world and if treatment for CTE is not found promptly, the effect of the dangerous sports will be seen in the players’ brains like never before. CTE has claimed countless lives on the record and even more that have never quite been proven. However, though most believe the cause is the constant head trauma experienced by players, perhaps this mystery does not stop at just that. The specific causes of CTE and still not completely known, and this paper intends to answer that with at least one cause: alcohol. Alcohol has been a favorite among many players and its presence is undeniable in the sporting community. Its effects on the liver, kidney, and other organs are clear already, and perhaps after this research and more, its effects on the brain can become clearer as well. A connection between alcohol and CTE can be seen here in this research and this link can be built upon in efforts to create a treatment for the horrible disease, eventually hoping to render this issue nonexistent.
Xenotransplantation and its adverse effects on the immunology of the human body and solutions
Authors: Krishna Chaitanya , Kethar Jothsna
Published: April 2023

The current demand in the U.S. for a transplant far exceeds of what is available. In fact, 22 people die each day because they do not get the necessary organ in time. With the human population growing, this problem will surely continue to get worse, but innovative solutions exist. Xenotransplantation, a method where a non-human organ is transplanted into a human, offers exciting potential like none seen before. An unlimited number of cells, tissues, and organs could be “manufactured” through genetic engineering, and this would truly be able to solve the high demand of organs in the United States. Obviously, tons of hurdles exist. Based on multiple sources, specific effects because of hidden diseases inside the graft, or organ of the animal, can cause damage to the patient which is alarming. Organ rejection is also deeply covered: the several types and what it entails in the body. Analyzing from various sources, the purpose of this research paper is to explain the adverse effects that transplantation can cause and to promote further research and investigation on combating the adversities presented.
Histone Lysine Demethylase 5B Role in Autism Spectrum Disorder
Authors: McClain Lily
Published: April 2023

KDM5B, a histone lysine demethylase “eraser” protein, is a transcriptional repressor of active promoter regions on histone 3 lysine K4. KDM5B is crucial to regulating gene expression and development. Previously, all mutations in KDM5B were described in cancer. High-performance sequencing revealed missense, frameshift, and nonsense mutations in KDM5B that can be linked to developmental disorders like autism spectrum disorder (ASD). This review summarizes KDM5B’s role in ASD and other developmental disorders.
The Genotoxicity of NPK using fluorescent staining methods on Peripheral Blood Mononuclear Cells (PBMC)
Authors: Kamesh Sukesh , Jemima Angel
Published: April 2023

NPK (Nitrogen, Phosphorus, Potassium) is a common fertilizer that farmers have been using for several years. In 2020, a 15-15-15 NPK was found to induce micronuclei formation when exposed to Juvenile African Catfish Clarias gariepinus (Helen 2020). This study examines the genotoxicity of a 19-19-19 NPK on PBMCs using fluorescent staining methods through an MTT Assay, EtBr/AO Staining, Comet Assay, and Micronucleus Assay. The objective of the study is to determine the in vitro cytotoxicity of NPK. The study found that when PBMCs were exposed to the LC50 value of NPK for 24 hours, apoptosis and necrosis occurred, as well as several polynucleated cells. While there is a substantial amount of evidence for genotoxicity in an in vitro setting, more studies will be needed to conclude whether NPK causes in vivo cytotoxicity.
Applications of CRISPR-Cas9 Technology to Treat CCR5 Tropic HIV-1
Authors: Tandon Ariv , Feist William
Published: April 2023

Human immunodeficiency virus type 1 (HIV-1) is most notable for its role in directly infecting and killing CD4 T cells in the immune system, which can lead to the acquisition of Acquired Immunodeficiency Syndrome (AIDS). Currently, there are no cures for HIV-1, leaving 37 million people with HIV-1 infections and no definitive treatment. Researchers are working towards developing long-term treatments for HIV-1 using CRISPR-Cas9. These therapies include genetically engineering antiviral resistance into vulnerable cell types and cutting out viral genomes from infected cells. This article will explain the HIV-1 life cycle in detail, give an overview of CRISPR-Cas9 technology, and then go into detail about the potential applications of CRISPR-Cas9 for the treatment of CCR5 Tropic HIV-1.
The Impact of Self-Regulated Learning on Academic Performance in High School Students
Authors: Dodge Benjamin , Solomon Robin
Published: April 2023

Many studies have found a strong correlation between academic performance and self-regulated learning (SRL). However, few studies have been conducted on high school students, fewer still examined specific SRL strategies instead of general themes or categories, and almost no studies considered the role that digital technology might play in SRL. This study uses data collected through an anonymous mixed-methods survey given to students at a rural high school. This survey collected information on both SRL strategies students use, and their GPA, used as a measure of academic performance. A portion on the survey focused on how students use digital technology, both for potential distraction and for SRL. Data on SRL strategies and digital technology use was sorted into categories by question, averaged, and then correlated with GPA to determine how certain strategies impacted academic performance, and how digital tool use or digital distraction impacted academic performance. This study found that most SRL strategies that correlated with academic success fell under two key modes: form-based studying and self-adaptive studying. In addition, while digital tool use did not correlate strongly with SRL, it correlated negatively with digital distraction. With this understanding, this study finds that there are distinct types of SRL implementation. Educators should consider this, adapting to student preferences when assisting with SRL implementation. Future research should also investigate the relative impact certain SRL skills or subcategories have over others.
The Effect of Talking to Plants in Order to Improve Emotions and Reduce Stress in High School Students
Authors: Gandhi Amelia
Published: April 2023

This study was designed to see if students could improve their emotional state and/or reduce stress by talking to a plant.  One of the major benefits of using plants to study feelings or stress is that implementation of the plant does not need to be standardized in order to measure mood or emotional feeling. Plants make excellent listeners because they do not talk back.  They allow a person to express their feelings and emotions without interruption or reciprocal feedback. Volunteer high school students, 9th through 12th grade, were given a plant and asked to document their pre-discussion feelings, talk to the plant for 15 minutes about anything they wanted, then document their post-discussion feelings. The study was conducted for 4 weeks through self-guided surveys.  The analysis showed a decrease in stress and nervousness across all grade-levels, with an increase in relaxation.
Sustaining Green Efforts: How Tech Parks in Bangalore Address Environmental Crises
Authors: Mehra Arshia , Lesoon Courtney
Published: April 2023

Bangalore, the capital of Karnataka is known as the Silicon Valley of India for the high number of ICT(Information and Communications Technology) companies and tech parks it has. The ICT industry has providedmillions of people with jobs in this city and has resulted in a population explosion, which has over time led toBangalore facing infrastructural crises along with strain on its natural resources. This paper discusses howsustainable architecture can set up a model for sustainability in perpetuity in Bangalore’s tech parks in the 21 stcentury.
Determinants of Adherence to Option B+ Antiretroviral Therapy among HIV Positive Pregnant Women Attending Antenatal Clinics at Tertiary Health Institutions in Anambra State
Authors: Silas Esther A , Nwankwo Clementina U
Published: April 2023

Purpose: The study ascertained determinants of adherence to option B+ antiretroviral therapy (ART) among HIV positive pregnant women attending antenatal clinics at tertiary health institutions in Anambra state.

Methodology: A cross-sectional descriptive design was adopted in conducting the study among HIV positive pregnant women attending antenatal clinics at tertiary health institutions in Anambra state. A sample size of one hundred and forty six (146) HIV positive pregnant women was selected by purposive and convenience sampling techniques. Adult AIDS Clinical Trial Group (AACTG) standardized questionnaire was used in data collection which were analyzed with IBM SPSS software database (version 25). Chi square was used for test of hypotheses at p < 0.05 level of significance.

Findings: Results revealed that the women with parity less than 4 (105(89%) were more adherent to ART; the women with primary education as highest level of education (13(92.9%) were more adherent to ART; the women within the age range 15-25 years (32(97%) were adherent; the women working in the informal sector (31 (96.9%) were more adherent to ART. The study also showed that there is no significant relationship between the women’s level of education, parity, age and adherence to ART but there is significant relationship between the women’s occupation and adherence to ART. From the study, it was ascertained that the HIV positive pregnant woman’s parity, level of education and age are not determinants of adherence to Option B+ ART but occupation of the women is.

Recommendations: Health care providers or mentor mothers in the health care facilities should give more attention to the HIV positive pregnant women working in the informal sector and unemployed than the women working in the formal sector in regards to their adherence to ART.
ASSESSING THE VALIDITY AND RELIABILITY OF ADAPTED QUESTIONNAIRES EXAMINING MALAYSIAN SCHOOL STUDENTS’ E-LEARNING PERCEPTIONS, PARTICIPATION, AND COPING STRATEGIES DURING THE COVID-19 PANDEMIC
Authors: AlSaqqaf Asmaa , Shaafi Nur Farha
Published: April 2023

This study aims to assess the validity and reliability of research instruments to investigate the level of Malaysian students’ participation in E-learning during the COVID-19 pandemic, examine their perceptions towards virtual learning, and propose strategies to increase students’ participation in online classes. The content validity of the research instruments was established by two e-learning experts, while the face validity was examined by seven school students. The adapted questionnaires and interview questions were modified based on the feedback obtained from the two-stage validity process. As for the reliability test, a simple random sampling method was employed, where a Google form was shared with school students with the help of their teachers at a particular school in Tuaran, Sabah, Malaysia. Out of the 43 students, who responded to the questionnaire, 29 were secondary school students while 14 belonged to primary school students; most of them were Year-6 students. Results demonstrated that Cronbach's alpha of the adapted questionnaires is 0.81, which indicates that the instrument is highly reliable and ready for data collection for the real study. This study highlights the need to develop a research scale that can cover the various aspects of e-learning participation among students, including the online and offline modes. Further research is recommended to examine the level of participation in online classes and perceptions towards e-learning among students in other parts of Malaysia as well as other regions.
OVERALL REVIEW ON ANNALYTICAL METHOD DEVELOPMENT AND VALIDATION OF CABOZANTINIB
Authors: Nuli Mohana Vamsi
Published: April 2023

In this review article determines the different analytical methods for the quantitative establishment of Cabozantinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical analytical method development of Cabozantinib requires valid analytical procedures for quantitative and qualitative analysis in Pharmaceuticals dosage formulations and human serum. This assessment explains that the superiority of the HPLC/LC-MS methods reviewed is based on the quantitative analysis of drugs in formulations, (API), biological fluids such as serum and plasma.
Kemalizm Üzerine Bir Düşünce Notu
Authors: ŞENGÖZ Murat
Published: April 2023

Kemalist felsefe, ilkesel olarak toplumda huzur, refah, barış ve güven iklimin tesis edilmesi noktasında önemli bir potansiyele sahiptir. Bu kapsamda Kemalizm benimsediği ilkeler nispetinde, etnik ve mezhepsel ayrımcılığa, toplumun bir kesiminin yok sayılarak sesinin kısılmasına, her türlü emperyal, tahakküm, asimilasyon ve tenkil politikalarına karşı korunaklı bir kale hükmündedir, çünkü Kemalizm homojen bir etnisite tarifinden ziyade kültürel bir birlikteliği tarif eder, çoğulculuğu temsil eder. Nitekim Kemalist düşünce; laik, demokratik, sosyal bir hukuk devletinin teminatı olarak kuşatıcı ve kapsayıcı bir paradigmayı temsil etmektedir. Bu kapsamda bu çalışmanın amacı, bilhassa tenkit ile tahkir sınırlarına riayet, ifrat ve tefrit tuzağına düşmeden ve gereksiz övgü ve yergilerden de imtina etmek ve Mustafa Kemal Atatürk’ün aydınlanmacı ve vizyoner kişiliği merkeze alınmak suretiyle, Türkiye Cumhuriyeti’nin kurucu felsefesi Kemalizm üzerinden yapılan tartışma ve istismarlarla alakalı olarak özgün bir değerlendirme gerçekleştirmektir. Bu çalışma, hermenötik bir nitel araştırmadır.ve araştırmada kullanılan tüm doküman ve yayınlar, literatür tarama tekniği ile elde edilen ikincil veri kaynaklarıdır.
PREPARACIONES ALIMENTARIAS CON MAYOR Y CON MENOR CONTENIDO DE (NaCl): MOTIVOS DE ELECCIÓN Y EMOCIONES RELACIONADAS SEGÚN ESTUDIANTES UNIVERSITARIOS. ESTUDIO TRANSVERSAL CUALI-CUANTITATIVO
Authors:   Universidad de Buenos Aires. Escuela de Nutrición, Facultad de Medicina. Ciudad Autónoma de Buenos Aires, Argentina, Vazquez Marisa Beatriz , Gulzej Micaela , Wallinger Marina , Watson Dana Zoe , Lema Silvia Noemí
Published: April 2023

Introduction: Excess sodium has been associated with an increased risk of cardiovascular disease. The objective was to study the reasons for choosing and the emotions related to foods with higher and lower salt content (NaCl) in students of the University of Buenos Aires (UBA) Methodology: Quali-quantitative observational study. Four Focus Groups (GF) were carried out with students of careers related and not related to Health, and a survey with the Check All That Apply (CATA) methodology aimed at students of university careers related to Health. Results: In the GFs carried out to identify reasons for choosing meals, important factors were considered as: "health, nutritional value and natural content", "price and accessibility in shops", "weight control", "convenience in preparation", "mood", "appearance, pleasant packaging, and well-known brand", and "sensory appeal". The factor "low sodium content in preparations" was not considered important. In the GFs carried out to identify emotions associated with food preparations with higher and lower salt content (NaCl), positive emotions predominated over negative and neutral ones. The preparations with higher salt content elicited more negative emotions in the GF of Health-related students. In the CATA responses (health-related students), the ham and cheese pie / empanadas and sandwich were characterized by reasons of convenience in preparation and higher salt content. The chicken sandwich and the vegetable pie / empanadas were associated with health and nutritional value (including lower salt content). Conclusion: The characterizations made by the students related to Health on these preparations are of interest and open the question of what will be the description of university students not related to Health careers. Funded by UBACYT research grant 20020170100502BA. Key words: food; sodium; emotions; students.
COMPARACIÓN DEL CONTENIDO DE SODIO DE ALIMENTOS DEL MERCADO ARGENTINO CON EL VALOR DEL RÓTULO
Authors:   Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Chulibert María E. , Barroso Santiago , Fenoglio Ignacio , Lupo Maela , Rigalli Alfredo ,   Centro Universitario de Estudios Medioambientales, Facultad de Medicina, Universidad Nacional de Rosario,   Laboratorio de Biología Ósea, Facultad de Medicina, Universidad Nacional de Rosario, Lombarte Mercedes
Published: April 2023

Introduction: sodium (Na) is an element abundant in nature and present in the water and food. The excessive consumption of Na, which mainly comes from processed foods, is a risk factor for the development of high blood pressure and cardiovascular disease. In Argentina, Na consumption doubles the maximum recommended consumption of 2000 mg/day. Objective: to evaluate the Na content of foods in the Argentine market and to compare the values of these with those declared in the nutritional labels. Materials and Methods: 97 products were selected from various categories (cold cuts, cheeses, sweetened beverages, cookies). The Na concentration was measured by emission spectroscopy and was expressed in mg Na/100 g/mL. Results: The median and range of the declared Na was for the foods analyzed was 630 [10-1833] (median [range]), while the measured Na was 645 [6.9-3278]; for non-alcoholic beverages, declared Na was 14 [0-46] and measured Na was 3.7 [0.8-36]. A significant difference was found between the Na values declared and measured in cold cuts and sweetened beverages (Wilcoxon test, p<0.05). Forty one percent of the measured value of Na in the foods analyzed are within the tolerance ± 20% required by The Argentine Food Code and 92% of the non-alcoholic beverages have a measured value lower than said interval. Conclusions: the declared and measured values are different for the categories of cold cuts and non-alcoholic beverages, which would prevent a correct estimation of the Na intake from these foods. Key words: sodium, foods; beverages; nutritional labelling; food composition.
Assessment of Nutritional, Chemical and Biological Potential of Cajanus cajan (L.) Millsp.
Authors: Dolly Barhaiya  , Dr. Vinod Dubey
Published: April 2023

In this paper deals with the genus Cajanus (Family: Fabaceae) consists of approximately 37 species, and Cajanus cajan (C. cajan) is a significant member of the genus. It is a commercial legume crop widely grown in sub-tropical and semi-arid tropical areas of the world. C. cajan is well known for its folk medicinal uses to treat various disorders, such as toothache, dizziness, diabetes, stomachache, female ailments and chronic infections. These properties have been linked to the presence of several value-added nutritional and bioactive components. Different solvent extracts from C. cajan (leaves, root, stem and seeds) have been evaluated for their phytochemical and biological activities, namely antioxidant, antimicrobial, antidiabetic, neuroprotective, and anti-inflammatory effects. Taken together, and considering the prominent nutraceutical and therapeutic properties of C. cajan, this review article focuses on the important details including ethnomedicinal uses, chemical composition, biological applications and some other medicinal aspects related to C. cajan nutraceutical and pharmacological applications
Nanorobotics in Cancer Theropy
Authors: Gouri M. Sontakke  , Prajakta R. Patil  , Shrutika S. Sakhare  , Anjali A. Patil  , Srushti S. Fartade
Published: April 2023

Nanorobotics is the technology of creating machines or robots at or close to the scale of a nanometre (10-9 metres), machines Constructed at the molecular level (nanomachines) may be used to cure the human body of its various ills.Traditionally nanotechnology dealt with design, synthesis and Application of materials along with devices at the nanometer scale. The application of nanotechnology in the field of health care and drug Delivery has come under great attention in recent times.Nanomaterials have a large surface area to Volume ratio and their physicochemical properties, such as Friction and interaction with other molecules, are distinct From equivalent materials at a larger scale. The most com-Mon use of nanotechnology in medicine has been in the Areas of developing novel therapeutic and imaging modal-Ities that have the potential to outperform the current state of The art in these areas. We will focus on the application of Nanotechnology to the development of smart drug deliv-Ery vehicles for cancer therapeutic applications. The most Common examples of these nanoscale delivery vehicles include polymeric nan Particles, dendrimers, nanoshells, liposomes, nucleic acid-Based nanoparticles, magnetic nanoparticles, and virus Nanoparticles. The following four types of nanorobotic systems have been developed and studied so far (a) large size nanomanipulators with nanoscale manipulation capability; (b) proicin- and DNA- hused bionanorobotic systems;c) Magnetically guided nano robotic system and d) bacterial based Nanorobotic etc.It can be used in many other applications.
Smart Pill Reminder Box
Authors: Dr. A. S. Telang  , Prathmesh Durge  , Ramesh Jatale  , Aniket Futane  , Priti Puri  , Prachi Avinashe  , Nikita Deshmukh
Published: April 2023

Smart pill reminders are devices that help patients remember to take their medications on time. These devices come in various forms, including mobile apps, wearable devices, and smart pill bottles. They use different techniques such as sound alerts, visual reminders, and text messages to alert patients when it's time to take their medication. Smart pill reminders can also track medication adherence and send reminders to caregivers or healthcare providers if the patient misses a dose. By using these devices, patients can improve medication adherence, which can lead to better health outcomes and reduce healthcare costs associated with medication nonadherence. However, it's important to note that smart pill reminders are not a substitute for good communication with healthcare providers and patients should always consult with their doctors before making any changes to their medication regimen
Neuroimaging Profile of drug-resistant Epilepsy from a Tertiary Care Center in South India
Authors: Navab M , Nagarajan K , P Nair Pradeep , Sivasubramaniyan KM
Published: April 2023

Background and aims: Drug-resistant epilepsy (DRE) is a common and important neurological problem to identify with scope for curative surgical treatment if underlying cause is delineated. There are very few prospective structured studies in our population. This study aimed to look at the neuroimaging profile of DRE presenting in a tertiary care center in South India. Materials and methods: All patients diagnosed clinically as DRE as per International League Against Epilepsy (ILAE) criteria and who underwent magnetic resonance imaging (MRI) over a period of 24 months were included in the study. Their clinical and MRI features were documented and analyzed. Results: A total of 150 patients diagnosed with DRE were included in the study. Clinically, 96 of them presented with generalized tonic-clonic seizures (GTCS), 36 with complex partial seizures (CPS), 14 with simple focal seizures, and two each with atonic seizures and focal seizures with secondary generalization. Magnetic resonance imaging (done in 1.5 T) was normal in 32%. In those with abnormal MRI, mesial temporal sclerosis (MTS) was the commonest pathology seen in 41.3%, followed by cortical malformations (6.7%), tumors (2.6%), vascular malformations (2.7%), and other nonspecific lesions (12%). Conclusion: The clinical and neuroimaging profile of DRE showed that DRE is more common in younger age (of less than 30 years); presents mainly with GTCS or CPS; mesial temporal sclerosis is the commonest underlying pathology which was bilateral in 8.6%; temporal lobe lesions predominate (49.3% of all DRE); and cortical malformation, low-grade tumors, and vascular lesions are other important causes.
Influence of Serum Levels of Vitamin D on Insulin Resistance in Patients with Type II Diabetes Mellitus
Authors: Prasad BN Raghvendra , Imran Tameem , Ahmed Rumaisa , ME Sumathi , Kumar Prasanna , C Chaitra
Published: April 2023

Background: Vitamin D plays an important role in bone and modulates mineral metabolism and immune function with probable link to several chronic and infectious conditions. In vivo studies have revealed that vitamin D deficiency reduces insulin secretion capacity of the islet beta cells in pancreas. Several studies have shown a correlation between vitamin D levels and insulin resistance, nonetheless, extensive studies showing the relationship between the two are lacking especially among southern Indian population. So the present study was aimed at evaluating the relationship between vitamin D and insulin resistance by using homeostatic model assessment-insulin resistance (HOMA-IR). Materials and methods: In a cross-sectional study, 184 people among which 92 were diabetic and 92 were nondiabetic were recruited at RL Jalappa Hospital, Kolar in the Department of Medicine between May 2018 and April 2019. Fasting serum insulin (I0), fasting plasma glucose (G0), hemoglobin A1c (HbA1C), renal function test, liver function test (LFT), lipid profile, and vitamin D levels were estimated. IBM SPSS version 22 was used for statistical analysis. Results: The prevalence of vitamin D deficiency in our study was (72) 78.2% among diabetic cases and (59) 64.1% among the nondiabetic controls, with the diabetic cases showing lower levels of vitamin D than the controls, however, it was not statistically significant. There was no significant difference in homeostatic model assessment-beta-cell function (HOMA-B) and HOMA-IR between vitamin D deficient and nondeficient groups among cases and controls. Conclusion: Vitamin D deficiency is prevalent in both type II diabetes mellitus (T2DM) as well as nondiabetic. Furthermore, there is no association between vitamin D deficiency and insulin resistance or beta-cell function.
The Deadly Duo of Hypertension and Diabetes in India: Further Affirmation from a New Epidemiological Study
Authors: G Metri Kashinath , Raghuram Nagaratna , S Ram C Venkata , Singh Amit , S Patil Suchitra , Mohanty Sriloy , Palukuru Sreedhar , HR Nagendra
Published: April 2023

Introduction: Hypertension is highly prevalent in patients with type II diabetes mellitus. India has some of the highest rates of diabetes and hypertension worldwide, but there is a lack of local data on the coexistence of these two risk factors. This study determined the prevalence of hypertension in patients with, or at high risk of, type II diabetes mellitus from across India. Methods: Data came from a nationwide trial evaluating the effects of yoga-based lifestyle modification for the prevention/management of type II diabetes. Participants were recruited based on randomized house-to-house screening in urban and rural areas from 65 districts of 29 states/union territories. Eligible individuals were aged 20–80 years and had diabetes or were at high risk of diabetes (IDRS ≥ 60). Anthropometric and demographic data were obtained, and resting blood pressure and blood glucose levels were recorded. Results: This analysis included data from 14,135 individuals. Of these, 25% had self-reported diabetes, 19% were diagnosed with diabetes during the trial, and 26.8% were at high risk for type II diabetes. In these three patient groups, hypertension prevalence rates were 58%, 41.0%, and 35.8%, respectively. The prevalence of hypertension was highest in the North East region and lowest in the North West. Conclusion: The high prevalence of hypertension in patients with, or at risk of diabetes, highlights the urgent need for policies to manage this population, who are at high risk of cardiovascular disease and death.
ACOMPANHAMENTO NUTRICIONAL NO PERÍODO PRÉ-GESTACIONAL, GESTACIONAL E PUERPERAL
Authors: Fardin Evelin Scalzer , Biral Janiely Sangiorgio , Cordeiro Jhenifer Medeiros , Carvalho Mayara Medeiros de Freitas
Published: April 2023

Introdução: O período gestacional requer muitas mudanças na vida da mulher, tais alterações têm por objetivo a garantia de fornecimento dos nutrientes necessários para a formação fetal. Os maus hábitos alimentares, com dietas pobres em nutrientes, ocasionam problemas na fecundação, formação e concepção do feto, além de aumentar o risco de mortalidade da gestante e do recém-nascido. Objetivo: Explicar, por meio de análise de artigos científicos, sobre os nutrientes necessários no período pré-gestacional, gestacional e puerperal, e a importância do acompanhamento nutricional. Metodologia: Essa é uma pesquisa qualitativa, reunindo informações através de pesquisas bibliográficas realizadas em bases de dados como, scielo, pubmed epositórios digitais de universidades brasileiras, em manuais do Ministério da Saúde, bem como em revistas científicas online, entre os anos de 2002 e 2022. Resultados e discussão: o acompanhamento nutricional e investigação prévia da sua feminina e masculina são fundamentais nesse momento minimizando os riscos de malformação fetal, irregularidade do peso ao nascer, retardamento do desenvolvimento da criança, mortes neonatais, entre outras complicações. Conclusão: Em suma ressaltamos a necessidade do acompanhamento nutricional na promoção da saúde, por meio da alimentação, visando boas condições de saúde da mãe e do bebê.
Um diálogo entre a psicanálise e a psiquiatria de ligação sobre a ansiedade de morte
Authors: Almeida Pedro
Published: April 2023

A ansiedade de morte tem sido um aspeto pouco abordado na teoria psicanalítica ao longo da sua história. Contudo, verificou-se recentemente um interesse renovado neste tema, que se concretiza por um movimento nascente de aproximação entre o pensamento psicanalítico e a Psiquiatria de Ligação com atuação nos Cuidados Paliativos. De forma a validar este esforço integrativo, apresenta-se o caso de uma mulher de 32 anos diagnosticada com adenocarcinoma gástrico em julho de 2019 e acompanhada por Psiquiatria de Ligação em Hospital Geral entre outubro/2019 e Novembro/2019, data da sua morte. Faz-se uma reflexão sobre a ansiedade de morte demonstrada pela doente, que, no último mês, foi acompanhada pela expressão de afetos que eram intoleráveis, causando impacto nos técnicos pelos comportamentos disruptivos associados. Numa visão psicanalítica, pretende-se demonstrar a importância desta ansiedade ser contida no seio da relação terapêutica e da necessidade de uma supervisão que atenda à contratransferência e às identificações inconscientes estabelecidas entre os técnicos e o doente. Para isso, recorre-se a alguns conceitos da obra de Wilfred Bion considerados relevantes na compreensão e gestão do caso, como função-alfa, identificação projetiva, modelo continente-conteúdo, entre outros.
Comentário realizado à conferência de Anna Maria Nicolò no XXX Colóquio da Sociedade Portuguesa de Psicanálise «A criança e a psicanálise», realizado em 3 e 4 de dezembro de 2021
Authors: Vicente Luísa Branco
Published: April 2023

N/A
Tecnología de potencial productivo de arroz (Oryza sativa L.) en el estado de Tabasco, México y su aportación a la soberanía alimentaria.
Authors: Moctezuma López Georgel , Pérez Miranda Ramiro , González Hernández Antonio , Ramírez Sánchez Eric Uriel
Published: April 2023

El mandato institucional del INIFAP (2018), es generar tecnologías agropecuarias y forestales para incrementar la productividad mediante la técnica de potencial productivo (PP). Se eligió al arroz por ser un cultivo importante en la dieta mexicana, además, existe un déficit en la producción de esta gramínea, el cual se subsana con importaciones que representan salida de divisas para México.  Los Distritos de Desarrollo Rural (DDR) de interés para el cultivo de arroz son: Cárdenas, Villahermosa y Emiliano Zapata (se tomó como ejemplo Cárdenas). Se consideraron dos tipos de potencial productivo: medio y alto. El objetivo del trabajo fue determinar el potencial productivo medio y alto para el cultivo del arroz cuantificado en miles de hectáreas para contribuir a la soberanía alimentaria del arroz en la canasta básica de los consumidores del país. El método para la determinación del potencial productivo se basó en la detección de tres categorías y nueve variables: i) clima (temperaturas máxima, media y mínima, y precipitación pluvial); ii) suelo (profundidad, textura y edafología) y iii) topografía (altitud y pendiente). Se identificaron con potencial productivo medio y alto, la cantidad de 257.9 miles de hectáreas susceptibles de ser sembradas. El principal DDR con potencial productivo alto fue Cárdenas con 69.7 % de la superficie que significan 74.5 miles de hectáreas de arroz. Finalmente, las detecciones de estas superficies agrícolas pueden ser incluidas dentro de los programas gubernamentales de apoyo a los productores arroceros y así incrementar sus niveles de ingreso para bienestar social.
Aportaciones para una política pública en el cultivo de palma de aceite
Authors: Ramírez-Hernández Bernardino , Almaguer-Vargas Gustavo
Published: April 2023

El estudio se centró en revisar la política gubernamental y pública agrícola nacional para el trópico húmedo, relacionada con el cultivo de la palma de aceite, haciendo hincapié si la producción contempla la conservación o el fomento de la agrobiodiversidad y si se lleva a cabo en la práctica. Se realizó la revisión bibliográfica sobre el tema, considerando estudios científicos, la normatividad y programas de fomento a la producción. Aunado a lo anterior, se visitó una huerta con prácticas orientadas a generar condiciones sustentables. Actualmente las plantaciones de palma de aceite se realizan bajo el sistema de monocultivo, dado que el único interés es adquirir mayor rentabilidad con base en un máximo rendimiento por hectárea. La política gubernamental y pública, omite promover plantaciones asociadas a la agrobiodiversidad y sostenibilidad, sin embargo, algunas opciones podrían ser implementar en los predios, cercos vivos con plantas medicinales, de ornato, árboles frutales, coberteras, entre otros.