bluuebunny/crossref_metadata_2025 huggingface dataset:
Is Fairyland for Everyone? Mapping online discourse on gender debates in Hungary
Authors: Szabó Hanna Dorottya
Published: November 2024

Over the past decade, Hungary has become a noteworthy example of democratic backsliding, marked by a pronounced shift towards conservative values and traditional gender roles within government policies. This trend, centred around Christian principles, has manifested in political campaigns actively opposing LGBTQ+ rights and the challenging of normative family structure. The resultant media campaigns and policy implementations have ignited extensive public discourse on gender and sexuality, prominently visible on social media platforms. This study conducts a qualitative analysis of the online discussion surrounding the LGBTQ+ children’s book, Fairyland Is for Everyone, to explore the contemporary gender discourse in Hungary. By examining social media comments under Hungarian online news articles, the research identifies three prevailing discursive lenses—heteronormative familism, neocolonialism, and diversity and inclusion—illustrating both the concurrent rise of anti-gender movements and the fortification of LGBTQ+ allyship in Hungary, while also considering broader transnational trends in LGBTQ+ rights and visibility.
Authentic conflicts in post-Yugoslavia: A model of a post-war generation’s communication system
Authors: Asboth Eva Tamara
Published: November 2024

The Yugoslav wars of secession in the 1990s left traces of the past among the societies living in the successor states. Those traces can be found within the collective memory of these societies, and are transmitted through various communication channels to the next generation. Today, this post-war and post-Yugoslav generation, born during or shortly after the violent conflicts, are young adults dealing with the recent past. Based on findings from life-story interviews that are examined and interpreted using the approach of sequence analysis, I elaborated a model of the transregional post-Yugoslavs’ communication system regarding the wars. I identified three communication practices on war-related topics by actively reflecting on the “Other,” which I present in this paper. During their adolescent years, post-Yugoslavs created their own narratives, and thus their own, authentic communication strategies in response to the “invisible war,” which still continues today, according to the post-Yugoslav generation.
Solutions of the minimal surface equation and of the Monge–Ampère equation near infinity
Authors: Han Qing , Wang Zhehui
Published: November 2024

Classical results assert that, under appropriate assumptions, solutions near infinity are asymptotic to linear functions for the minimal surface equation and to quadratic polynomials for the Monge–Ampère equation for dimension

n
≥
3

n\geq 3

, with an extra logarithmic term for

n
=
2

n=2

.
Via Kelvin transforms, we characterize remainders in the asymptotic expansions by a single function near the origin.
Such a function is smooth in the entire neighborhood of the origin for the minimal surface equation in every dimension and for the Monge–Ampère equation in even dimension, but only

C

n
−
1

,
α

C^{n-1,\alpha}

for the Monge–Ampère equation in odd dimension 𝑛, for any

α
∈

(
0
,
1
)

\alpha\in(0,1)

.
Embeddings of anisotropic Sobolev spaces into spaces of anisotropic Hölder-continuous functions
Authors: Eddine Nabil Chems , Repovš Dušan D.
Published: November 2024

We introduce a novel framework for embedding anisotropic variable exponent Sobolev spaces into spaces of anisotropic variable exponent Hölder-continuous functions within rectangular domains. We establish a foundational approach to extend the concept of Hölder continuity to anisotropic settings with variable exponents, providing deeper insight into the regularity of functions across different directions. Our results not only broaden the understanding of anisotropic function spaces but also open new avenues for applications in mathematical and applied sciences.
Genesis 9:1–7: P, H or D?
Authors: Amar Itzhak
Published: November 2024

Gen 9:1–7 has traditionally been regarded as the Priestly epilogue to the Priestly flood story. In this article, I aim to refute this view and demonstrate that this unit, which incorporates various motifs from Priestly literature as well as from Deuteronomistic (D) and Holiness Code (H) texts, was edited by the Holiness School (HS) during the time of the return to Zion after the exile. Its stated purpose was an all-out struggle against the animals that threatened the sparsely populated state of Yehud.
Arbeit aus Liebe? Die fotografischen Beiträge des DDR-Erziehungsratgebers Entwicklungswunder Mensch
Authors: Müller Annekathrin
Published: November 2024

This essay examines the photographic contributions to Entwicklungswunder Mensch, a book published in 1980 in the German Democratic Republic, edited by photographer Evelyn Richter together with text author Hans-Dieter Schmidt. The publication was meant to address everybody interested in raising children and understanding their psychological development. Examining its representation of care work, this essay shows that the book’s authors tried to convey the image of a loving approach to the child while insisting on the priorization of children’s needs. This demand is put in the context of the sociopolitical background of the late GDR, and it becomes clear that the book set out as a counter proposal to the status of care work in socialist East Germany.
Thyrotropin reference interval in older adults
Authors: Zhai Xiaodan , Li Yongze , Teng Xiaochun , Teng Weiping , Shi Xiaoguang , Shan Zhongyan
Published: November 2024

It is estimated that by the year 2050, 16% of the world’s population will be 65 years old and above. As the global aging population continues to grow, there is an increasing focus on thyroid disorders among older individuals. Thyrotropin is widely used in diagnosing subclinical thyroid diseases due to its high sensitivity as an indicator of changes in thyroid function. However, thyrotropin levels change with age, and different reference intervals have been proposed in various studies. The variation in thyrotropin ranges among older adults is probably caused by the heterogeneity of the studied population. This review aims to provide an overview of the existing literature on thyrotropin reference intervals in older adults and their distinction as adaptive or pathologic. Recent research indicates that older individuals may have slightly elevated levels of thyrotropin and higher upper limits of reference intervals. Therefore, a higher thyrotropin threshold for diagnosing and treating subclinical hypothyroidism in the elderly seems reasonable.
Gene expression profile analysis of subregions of the adult female reproductive tract in the brown anole, Anolis sagrei
Authors: Kircher Bonnie K , Liu Bin , Bramble Matthew D , Moses Malcolm M , Behringer Richard R
Published: November 2024

In brief

Modes of reproduction across limbed vertebrates are diverse, but the molecular mechanisms required for the development and maintenance of reproductive tract tissue architecture are poorly understood. This paper describes gene expression changes across the regions of the reproductive tract of the adult female brown anole, Anolis sagrei.

The morphological diversity and functional role of the organs of the female reproductive system across tetrapods (limbed vertebrates) are relatively poorly understood. Although some features are morphologically similar, species-specific modification makes comparisons between species and inference about evolutionary origins challenging. In combination with the study of morphological changes, studying differences in gene expression in the adult reproductive system in diverse species can clarify the function of each organ. Here, we use the brown anole, Anolis sagrei, to study gene expression differences within the reproductive tract of the adult female. We generated gene expression profiles of four biological replicates of the three regions of the female reproductive tract, the infundibulum, glandular uterus, and nonglandular uterus, by RNA-sequencing. We aligned reads to the recently published A. sagrei genome and identified significantly differentially expressed genes between the regions using DESeq2. Each organ expressed approximately 14,600 genes, and comparison of gene expression profiles between organs revealed between 367 and 883 differentially expressed genes. We identify shared and region-specific transcriptional signatures for the three regions and compare gene expression in the brown anole reproductive tract to known gene expression patterns in other tetrapods. We find that genes in the Hox cluster have an anterior–posterior, collinear expression pattern as has been described in mammals. We also define a secretome for the glandular uterus. These data provide fundamental information for functional studies of the reproductive tract organs in the brown anole and an important phylogenetic anchor for comparative studies of the evolution of the female reproductive tract.
Metabolic syndrome impairs endometrial functioning and early pregnancy: an in vivo study
Authors: Carnovale Noelia , Velazquez Candela , Valle Sofía del , Simone Julieta , Méndez García Luis Francisco , Fritzler Analy , Palazzi Jorge , Stella Inés , Bilotas Mariela , Meresman Gabriela
Published: November 2024

In brief

This study demonstrated that metabolic syndrome (MetS) in mice disrupts the estrous cycle, increases progesterone levels and alters the endometrial structure, resulting in impaired reproductive success. Treatment with metformin effectively reversed these effects, restoring hormonal balance and normal endometrial architecture and improving reproductive outcomes.

MetS is increasingly associated with impaired reproductive health. This study aimed to assess the endometrial characteristics and reproductive outcomes of a female MetS mouse model and evaluate metformin’s therapeutic effects. Twenty-one-day-old female C57BL/6 mice were randomly divided into a high-fat (HF) diet group (n = 50) and a control group (n = 30) that received standard chow. After 11 weeks, a subset of HF mice (n = 25) was given oral metformin at 300 mg/kg/day, while the other ones continued on HF diet. After 15 weeks, mice were either sacrificed during estrus or mated and euthanized on day 7.5 of pregnancy (n = 15 per group). The estrous cycle, progesterone and estradiol levels, uterine morphology, endometrial cell proliferation, reproductive performance and metformin’s treatment effects were assessed. Mice on the HF diet developed MetS, which was characterized by moderate glycemic dysregulation, increased cholesterol, insulin resistance and central obesity. Experimental MetS caused estrous cycle disruptions and increased serum progesterone levels, which were normalized by metformin. MetS also affected endometrial histology, producing hyperplasia and altering cell proliferation, while metformin restored the normal endometrial architecture by inhibiting cell proliferation. In addition, MetS impaired the reproductive success by delaying coitus and reducing the ratio of implantation sites to corpora lutea, both of which were rectified by metformin. In conclusion, MetS adversely affects reproductive function, but metformin offers improvement. Our findings highlight the need for further research on the impact of MetS on reproduction and the exploration of treatments to enhance reproductive health in women with MetS.
Genetic, Metabolic, and Proteomic Polymorphisms and Clinical Phenotypes of Sepsis
Authors: Kovzel V. A. , Davydova L. A. , Lapina T. A. , Semushkina A. A. , Gutnikov A. I.
Published: November 2024

The heterogeneity of sepsis patient populations remains an unresolved issue, hindering the development of effective therapeutic strategies and disease prognostic tools. Classification of diverse sepsis patients by molecular endotypes, together with multi-omics profiling, enables a more personalized treatment approach. Studying the immune response, genomic, metabolomic and proteomic profiles of sepsis patients will enable clinical phenotyping of this diverse population and the development of a precision approach to the diagnosis, prognosis and treatment of sepsis and septic shock.

   The aim of the review was to discuss sepsis subtypes as identified by profiling of patient genomic, metabolic, and proteomic data and present the latest approaches addressing the heterogeneity of sepsis patient populations, such as multi-omics endotyping and clinical phenotyping, which may aid in targeted therapy and optimization of diagnosis and therapy.

   The keywords «sepsis omics», «sepsis endotypes», and «sepsis heterogeneity» were used to search PubMed databases without language restrictions. From over 300 sources, 120 were selected for analysis as being most relevant to the aim of the review. More than half of these were published within the last five years. Criteria for excluding sources were their inconsistency with the aims of the review and their low informativeness. This review discusses the different types of immune responses, the impact of patient population heterogeneity on therapeutic interventions, and current perspectives on phenotyping sepsis patients. Despite the limitations of centralized collection of clinical information, cluster analysis of large data sets and the role of immune response genomics, metabolomics, and proteomics are beginning to dominate the prognosis and treatment of sepsis. Establishing links between all these elements and attempting clinical phenotyping of sepsis, including subtype analysis, appear to be critical in the search for personalized treatment approaches in the near future.

   Conclusion. Currently, the widely accepted goal in sepsis management is early detection and initiation of therapy to prevent the development of irreversible septic shock and multiorgan failure syndrome. Personalized genetic, metabolomic and proteomic profiling of the patient seems to be an intriguing and promising avenue in the search for new treatment strategies in sepsis.
Juvenile Parkinsonism Associated With Dihydropyrimidinase Deficiency
Authors: Li Jiaqing , Xu Sanqing
Published: November 2024

Juvenile parkinsonism is an exceedingly rare condition in which clinical signs of parkinsonism manifest before 21 years of age. Although the genetic underpinnings of this disorder are increasingly recognized, the full range of inherited metabolic contributors remains undefined. We present the first case of levodopa-responsive juvenile parkinsonism associated with dihydropyrimidinase deficiency caused by a novel DPYS variant. A 13-year-old patient presented with rapid progression of dysphagia, dysarthria, and loss of ambulation over 18 months. Whole-exome sequencing revealed compound heterozygous variants in the DPYS gene (NM_001385: c.1393C>T, p.R465X, and c.905G>A, p.R302Q). In silico analysis predicted both variants to be pathogenic. Further urinary metabolome analysis demonstrated markedly elevated dihydrouracil and dihydrothymine levels, confirming impaired pyrimidine metabolism. Levodopa treatment effectively relieved the patient’s motor symptoms. This report identifies DPYS as a novel genetic cause of juvenile parkinsonism and underscores the potential efficacy of levodopa therapy in managing motor dysfunction in DYPS-related parkinsonism.
(Des)cuidados: cuerpo, velocidad y desmaterialización
Authors: Bonavitta Paola , Sarmiento Laura
Published: November 2024

Este ensayo examina la autoetnografía como forma de comprender el mundo. Así, apostamos por una ciencia que da prioridad al cuerpo, que cuestiona el quehacer positivista y que privilegia el punto de vista feminista. Partimos, también, de una epistemología de los afectos y de las emociones, que pone en el centro la vida misma. Desde esta perspectiva, dialogamos sobre y acerca de una ética de los cuidados. Específicamente, nos centramos en la maternidad como acto político y como acción transformadora que enfrenta la demanda permanente del sistema capitalista. La maternidad, como institución no servil del poder, no existe como tal; sin embargo, nosotras habitamos nuestros cuerpos integralmente según sus capacidades y sus potencias, lo que nos permite hacer de dicha institución un tejido cotidiano.
Participación de las mujeres en la pesca artesanal en el norte del Perú en el contexto del cambio climático
Authors: Alarcón Guadalupe , Tam Jorge , Zavala José
Published: November 2024

En Perú, la participación de la mujer en la pesca artesanal ha sido invisibilizada y poco estudiada, en especial porque su participación en el proceso de extracción pesquera está restringida en muchas comunidades artesanales. Por tal motivo, el objetivo del presente estudio es caracterizar la participación de las mujeres involucradas en la pesca artesanal en las caletas de El Ñuro y Los Órganos del norte del Perú, bajo el contexto del cambio climático. A través de métodos participativos, se analizaron los capitales y medios de vida de las mujeres, su participación en la cadena productiva de la pesca artesanal, y el co-diseño de acciones afirmativas para su adaptación al cambio climático. Se encontró que las mujeres participan en procesos pesqueros como: preparación, manipuleo, ventaprimaria, transporte y venta final; sin embargo, para futuros proyectos de pesca artesanal con enfoque de género son necesarias acciones afirmativas como el procesamiento con valor agregado, la producción de biofertilizantes, el ecoturismo, la acuicultura sostenible, la gastronomía y las artesanías marinas.
La transcendencia de la escritura en el entorno digital universitario
Authors: Rossette García Javier , Clemente Martínez Gabriela
Published: November 2024

Desarrollado bajo técnica documental, el presente manuscrito tiene como finalidad exponer los argumentos de la comunidad científica sobre el acto comunicativo escrito, así como su trascendencia global al difundirse a través de los dispositivos electrónicos en formato digital. Esto conlleva al planteamiento de posturas a favor y en contra de este fenómeno, donde el análisis pone énfasis tanto en las opiniones a favor de la escritura manual (texto analógico) y quienes están a favor de la escritura electrónica (texto digitalizado). De ahí que, profesores y profesoras tienen que advertir el papel que juegan los nuevos entornos de  aprendizaje, saber utilizarlos y, a su vez, crear una conciencia axiológica en el estudiantado, sobre la importancia del uso normativo de la lengua que, bajo cualquier circunstancia o contexto, lleva implícita un valor histórico-social perenne.
La nominalización del “científico” y “científica” durante la Revolución Científica
Authors: Laris Pardo Jorge Alejandro
Published: November 2024

En la historiografía de la ciencia actual, que está fuertemente influenciada por corrientes anglosajonas, se ha vuelto obligatorio señalar que William Whewell (1794-1866) acuñó en 1834 la palabra “scientist” en inglés, debido a la dificultad de encontrar una voz equivalente al alemán “natur-forscher”. El propósito de este documento es cuestionar si es correcto aplicar esta reflexión para la evolución de la palabra “científico” o “científica”. Con ello en mente, se sustenta el estudio de la nominalización de esta palabra en el español. Se estudian fuentes históricas con el auxilio de herramientas digitales como el Corpus del Diccionario histórico de la lengua española (CDH), el Corpus Diacrónico del español (CORDE) y el Nuevo Tesoro Lexicográfico de la Lengua Española (NTLLE) de la Real Academia de la Lengua Española; el Diccionario de la Ciencia y de la Técnica del Renacimiento de la Universidad de Salamanca; así como la base de datos de Google Ngram. Estasbúsquedas se han complementado con testimonios que el autor ha recabado a lo largo de sus investigaciones y un diálogo con la historiografía pertinente. Se concluye que la evolución de nuestra palabra “científica” o “científica” no corresponde a la anglosajona. Por el contrario, su origen se encuentra en un largo proceso de nominalización.
Prácticas funerarias de la Antigüedad Clásica: griegos, etruscos y romanos
Authors: Valenciano Minor Herrera
Published: November 2024

Por medio del estudio de las acciones funerarias de las civilizaciones griega, etrusca y romana antiguas es posible reconocer no solo la dedicación y el respeto dirigido hacia estas, sino, y quizá lo más importante, la necesidad de honrar la memoria de los muertos y procurar con esto su protección, hecho que es heredado incluso por otras corrientes religiosas, por ejemplo, el cristianismo. Así las cosas, el presente artículo consiste en una exposición y análisis de las prácticas funerarias de las civilizaciones griega, etrusca y romana antiguas para determinar el sentido simbólico de estas y la importancia que poseían para dichas culturas. De esta manera, para explicar las prácticas funerarias de dichas civilizaciones, habrá que recurrir, cuando convenga, a ejemplos tomados de la Ilíada de Homero, en el caso de los griegos; en el caso de los etruscos, de los registros arqueológicos existentes, y del texto de la Eneida de Virgilio, en el caso romano, por ser considerados monumentos (en su sentido etimológico ) literarios y culturales.
PARTNERSHIP DISSOLUTION IN AUSTRIA DURING MULTIPLE CRISES, 2018-2023
Authors: Buber-Ennser Isabella , Berghammer Caroline , Winkler-Dworak Maria
Published: November 2024

At the onset of the COVID-19 pandemic in 2020, divorce rates across European countries significantly declined and remained low through 2023. This sustained low level is notable, especially given the potential for a rebound in postponed divorces. This study examines partnership dissolution in Austria from 2018 to 2023, covering the pandemic and a subsequent period of high inflation. It specifically investigates the role of socioeconomic and family characteristics. The analysis draws on 24 quarterly waves from the Austrian Labour Force Surveys, focusing on cohabiting and married couples aged 20 to 54 (n=32,913 couples). Households participated in five consecutive quarters. Changes in partnership status across waves were analysed using random effects logistic panel regression models. The dissolution of partnerships sharply declined during the pandemic (2020-22) and remained at a lower level throughout the period of high inflation (2022-23). The risk of separation decreased most significantly in two groups: couples without children (compared to those with children, especially two or more) and couples with low to medium education levels. We interpret the less pronounced decline in dissolution risk among parents as an indication of greater strain, particularly due to work-family conflicts. Additionally, the reduced rate of union dissolutions among low- and medium–educated couples likely reflects financial challenges in setting up a second household, exacerbated by inflation and rising living costs. The economic barriers to partnership dissolution may be considered a social problem.
A-optimal design for cubic model without a 3-way effect for mixture experiment
Authors: Panda Mahesh Kumar
Published: November 2024

In this article, we obtain a saturated A-optimal design for the cubic model without a 3-way effect for mixture experiment and get a general formula of the weights. The necessary and sufficient condition of the A-optimality criterion is confirmed by using the corresponding equivalence theorem.
Report of the live large whale stranding response workshop
Authors:   International Fund for Animal Welfare, Sharp Sarah M. , Moore Michael J. ,   Woods Hole Oceanographic Institution, Harms Craig A. ,   North Carolina State University, College of Veterinary Medicine and Center for Marine Sciences and Technology, Wilkin Sarah M. ,   NOAA Marine Mammal Health and Stranding Response Program, Sharp W. Brian ,   International Fund for Animal Welfare, Patchett Kristen M. ,   International Fund for Animal Welfare, Rose Kathryn S. ,   International Fund for Animal Welfare
Published: November 2024

Reasoned triage and management of live large whale stranding events prompted this workshop. Safety is paramount for humans and must be mitigated for them and whales during responses. Clinical assessment is critical, with emaciation and poor prognosis often worsening welfare if released. Accurate length and estimated weight data are essential. Supportive care and treatments depend on understanding the underlying pathophysiology of stranding. Maintaining an airway, monitoring breathing, minimizing stress, protecting eyes, modulating temperature, and preventing sunburn are priorities. Additional strategies can include mild sedation, fluid administration, and flipper excavation to relieve pressure. Tools to indicate post-release survival include photographs, genetic samples, paint sticks, and identification, VHF, or satellite-linked tags. Acceptable rescue techniques included towing offshore with a tackle or lines over or under the body and around the axillae, inflatable lift bags, and trenching. Nets and towing by the flukes are unsuitable. Refloating of stranded large whales can be considered if a clinical examination suggests a favorable prognosis, and a release method could be safely undertaken without undue stress and trauma to the animal. However, in many cases euthanasia is the most humane option if practical, or letting nature take its course if need be.
ANALYSIS OF AXISYMMETRIC RADIALLY EXPANDING FREE-LIQUID SHEETS BY MEANS OF LUBRICATION THEORY
Authors: Gyurkovich Alexander , Grimm Pierre , Mehring Carsten
Published: November 2024

A nonlinear lubrication model for the analysis of inviscid radially expanding modulated free-liquid sheets
is presented. Starting from the dimensionless continuity and momentum equations for incompressible, inviscid axisymmetric liquid sheets without surrounding gas-phase effects governing equations for sheet thickness, sheet centerline location in transverse direction as well as mean radial and transverse velocity components are derived. The resulting system of partial differential equation together with proper boundary conditions is solved numerically using central differences and a high-order Runge-Kutta ordinary
differential equation (ODE)-solver. The model was validated with experimental data for the case of a stationary
water bell and by comparing numerical results for modulated radially expanding sheets and small disturbance amplitudes with results obtained from linear theories (i.e., in terms of observed wavelengths) and experimental data (in terms of film disturbance envelope) for the same flow cases. For cases with larger disturbance amplitudes, nonlinear mode coupling between sinuous and varicose modes leads to film
rupture, similar to that observed for planar sheets. Predicted film break-up lengths in the nonlinear regime
show good agreement with experimental data and with highly resolved volume of fluid (VOF) simulations.
Optimised biopolymer-based capsules for enhancing the mechanical and self-healing properties of asphalt mixtures
Authors: Norambuena-Contreras Jose , Concha Jose L. , Valdes-Vidal Gonzalo , Wood Clare
Published: November 2024

The growing need to enhance our road infrastructure has driven the development of several innovative techniques in recent years. Among these advancements, encapsulated rejuvenator solutions for extrinsic self-healing asphalt have emerged as a significant topic of interest. This paper evaluates the effect of optimised capsules containing vegetal oil as a biorejuvenator on the physical, mechanical, and self-healing properties of dense asphalt mixtures. In this study, previously optimised polynuclear alginate-based capsules were synthesised using vibrating jet technology with 5% wt. calcium chloride and a biopolymer-to oil mass ratio 1:7. Optimised capsules were incorporated into the asphalt mixture at concentrations of 0.125% wt., 0.25% wt., and 0.5% wt. Their spatial distribution within the asphalt mixtures was evaluated using an alternative method to CT scans, which utilised machine learning-based image analysis of the core asphalt samples. The main findings of this research are as follows: (1) a uniform distribution of capsules was achieved throughout the asphalt mixture, although clustering was observed at higher concentrations. (2) The capsules successfully survived the asphalt manufacturing process, and mechanical tests highlighted the adhesive properties of the alginate encapsulation material. (3) Asphalt samples with 0.125% wt. capsules exhibited mechanical performance comparable to samples without capsules; however, this content did not significantly enhance their self-healing properties. In contrast, self-healing capabilities were significantly enhanced with a capsule content greater than or equal to 0.25% wt.; however, this enhancement slightly affected some physical–mechanical properties of the dense asphalt mixture.
PF4 inhibits ferroptosis-mediated intracerebral hemorrhage through modulating the CXCR3/AKT1/SLC7A11 signaling pathway
Authors: Hu Na , Zhang Guohong , An Liping , Wang Wei , An Ran , Li Yunfeng
Published: November 2024

Ferroptosis plays a crucial role in the secondary pathophysiological damage to brain tissue surrounding hematomas after intracerebral hemorrhage (ICH). While platelet factor 4 (PF4) is known to promote regeneration following peripheral nerve injury, its role in brain tissue repair after cerebral hemorrhage remains unclear. In this study, Hemin-induced PC12 cells were treated with various inhibitors and assessed for viability, oxidative stress, and ferroptosis using a combination of assays, including CCK-8 (Cell Counting Kit-8), EdU (5-Ethynyl-2’-deoxyuridine), flow cytometry, and immunofluorescence. ICH cells were also treated with recombinant PF4 (Rm-PF4) and a CXCR3 antagonist (AMG487) to investigate the mechanism by which Rm-PF4 influences Hemin-induced PC12 cell injury and inflammation. Subsequently, ICH mouse models were established via collagenase injection. Neurological function in these mice was evaluated using the Cylinder and Corner tests. Histopathological damage to brain tissue was analyzed through HE, TUNEL, and Nissl staining, as well as immunohistochemistry, to further explore the role of Rm-PF4 in controlling neuroinflammation in vivo. Results showed that Rm-PF4 inhibited Hemin-mediated ferroptosis-induced PC12 cell damage and inflammation by activating the CXCR3/AKT1/SLC7A11 signaling pathway. Blocking the CXCR3/AKT1/SLC7A11 pathway partially reversed PF4's protective effects on Hemin-induced PC12 cells.In ICH mice, pro-inflammatory marker CD16 (3rd day) and anti-inflammatory marker Arg1 (7th day) were significantly decreased and increased, respectively (p<0.05). IL-6, TNF-α, and IL-1β levels were down-regulated in brain tissues after Rm-PF4 injection, which was significantly reversed by AMG487. PF4 inhibits ferroptosis after ICH reduced PC12 cell damage and the inflammatory response via activating the CXCR3/AKT1/SLC7A11 pathway.
Using a Cross-Sectional Analysis of Age-Related Variations in Anthropometric Indices and their Association with Cardiometabolic Health in Adult Men
Authors: Nawfal Kanaan Ibrahim , Tiwari Sandhya , Tiwari Sandeep , Haq Mir Ahsan Ul
Published: November 2024

Background. Age-related changes in anthropometric indices and their association with cardiometabolic health markers are crucial for understanding health risks in adult men.

Objectives. The study aimed to assess age-related variations in anthropometric indices and their correlation with health markers, highlighting potential cardiometabolic health risks in adult men.

Materials and methods. A total of 200 men, aged 26 to 50 years, from Delhi-National Capital Region (NCR), India, were sampled using a multistage random sampling technique and divided into 5 age groups, each including 40 individuals. This study examined variations in body measurements such as the hip circumference (HC), waist circumference (WC), body mass index (BMI), and neck circumference (NC) across different age groups, as well as their relationship to health markers like HbA1c and lipid profile. Anthropometric measurements were taken in a standardized environment, and blood samples were taken under fasting conditions for lipid profile and HbA1c measurement. With SPSS software, descriptive statistics, a one-way ANOVA, and the Pearson correlation coefficients were used to analyze the data.

Results. Significant age-related differences were found in NC and WC, with NC increasing from 39.61 ± 2.53 cm to 41.20 ± 2.63 cm and WC rising from 89.68 ± 12.08 cm to 98.80 ± 9.90 cm, indicating a trend toward central obesity. BMI and HC showed no considerable variation across age groups. A one-way ANOVA revealed significant differences in NC (F = 3.586, p = 0.008) and WC (F = 6.020, p = 0.005). Pearson’s correlations indicated that NC, BMI, and WC were positively correlated with triglycerides, LDL, and VLDL levels (p < 0.05), while no notable correlations were observed for HbA1c.

Conclusions. The study underscores the existence of significant age-related increases in NC and WC, suggesting heightened risks of abdominal obesity and cardiometabolic health issues in older men. Monitoring these anthropometric indices is vital for the early detection of health risks in adult males.
The Great Vindhyan Basin of Northern India
Authors: Krishnan M. S. , Swaminath J.
Published: November 2024

The Vindhyan Basin, extending from Sasaram to Agra and Nimach, occupies an area of about 70,000 sq. miles. The Semri Series, constituting the Lower Vindhyans, show mainly argillaceous and calcareous strata with glauconitic beds and volcanics. They were subjected to diastrophism before the Upper Vindhyans, composed mainly of arenaceous and argillaceous strata, were laid down. The shape of the basin indicates that it must originally have extended in to the Lesser Himalayan region of Nepal and Garhwal-Simla. Though the Vindhyan formations have not yielded any fossils useful for a clear determination of their age, they are considered to be mainly Cambrian.

The Lesser Himalayan region contains several unfossiliferous formations (Simla Slates, Jaunsars, Blainis, and Infra Krol-Krol-Tal Series) whose stratigraphic correlation has so far hinged on the view that the Blaini boulder beds are of Talchir age. Consequently the Infra-Krol, Krol and Tal Series have been correlated with the Mesozoic systems.

Recent work by Boileau and his associates in the Lesser Himalayas has led them to offer a new correlation. Boileau suggests that the Vindhyans represent a good part of the Palaeozoic; that the Blaini tillites are contemporaneous with an ice age at the heginning of the Upper Vindhyan, following the diastrophism which affected the Semri Series; and that a part of the Tals are the equivalents of the Talchirs.

In this paper the authors review the stratigraphy of the regions concerned and bring out the implications of the interesting correlations suggested by Boileau.
Pebble Fabric Analysis of the Talchir Boulder Bed in the Jharia Coalfield, Bihar
Authors: Ganju P. N. , Srivastava V. K.
Published: November 2024

The Talchir boulder bed in the Jharia Coalfield, has been studied with special reference to the fabric of the particles that constitute it and an attempt has been made to determine the nature and direction of the depositing agency.

Studies on pebble orientation show that the particles are preferentially oriented in all the sections studied and exhibit an upstream imbrication. The inclination is of the same order of magnitude as determined by Cailleux for fluvial gravels.

The streams that deposited these ancient gravels came from a general westerly and north-westerly direction as shown by the fabric diagrams. It is inferred that the source of the debris was the moraine material left by melting glaciers and that the debris was transported east and south-eastwards by fast flowing streams into the basin of deposition.
Tertiary Stratigraphic Correlation in the Indo-Pacific Region and Australia
Authors: Glaessner M. F.
Published: November 2024

A correlation of the Tertiary stratal sequences throughout the area from India to the islands of the Western Pacific and to Australia is attempted. As far as it concerns the Miocene, reference is made to Drooger's work on the stratigraphic distribution of Miogypsinidae and of pelagic Foraminifera. Apparent discrepancies reported from Formosa and Saipan are examined and the factual data are found to be compatible with Drooger's dating of the entry of Orbulina. Abundant information from south. eastern Australia on foraminiferal biostratigraphy is reviewed. Upper Eocene to Miocene foraminiferal zones can be regionally recognised, among them the important Globigerinoides bispherica zone. While its placing in the Helvetian in accordance with Drooger's findings in Europe is compatible with n!'!w observations and is tentatively accepted, a Burdigalian age cannot be ruled out on present evidence. The occurrence of Paleocene, Eocene and Miocene distinctive markers leads to the first fairly detailed correlation of Australian and Indo-Pacific Tertiary strata.
A Note on the Petrology of Apatite-Biotite-Monchiquite from Giridih Coalfield, Bihar
Authors: Subrahmanyam N. V. R. , Raghu Nandan K. R.
Published: November 2024

A re-examination of Holland's collection of mica peridotites from Giridih coalfield is presented with a detailed petrographic description of the rocks which entitles them to be specifically termed as 'apatite-biotite-monchiquites', recorded as such for the first time from the Lower Gondwana coalfields of India.

The order and periods of crystallisation of the constituent minerals are given in a graphical form by plotting the modal analysis to discuss the petrogenesis. The authors consider that the first genetic class of minerals, viz. olivine and augite crystallised and accumulated at place before the emplacement of the magma into the country rock. After emplacement, the minerals of the second genetic class, viz. apatite, biotite and perovskite formed either from the condensation of a volatile phase or hydrous environment with quick lowering of temperature. With the abrupt termination of favourable temperature conditions, the last remnants of the liquid froze into interstitial glass, most of which soon devitrified into analcite.
Operator Variation in the Estimation of Percentage Heavy Minerals
Authors: Gundu Rao C.
Published: November 2024

Griffiths and Rosenfeld have demonstrated that all experimental procedures are characterised by two sources of error: (i) constant bias distinctive of each operator and (ii) inconsistency within one operator and among a group of operators. An experiment was organised by the writer to evaluate operator variation that may enter in the estimation of percentage heavy minerals by using a large sample of Ariyalur sandstone (Trichinopoly Cretaceous) as an example. This experiment revealed that heavy mineral work also involves, as many other experimental endeavours, sources of error such as (a) experimental (b) operator variation (c) constant bias within individual operators and (d) inconsistency of operators from sample to sample. It is pointed out that if all these sources of error are not properly evaluated, 'isolated and controlled by suitable analysis of variance techniques, the results of heavy mineral work will be far from any real value.
Ampangabeite from Hazaribagh District, Bihar, India
Authors: Rama Rao Y. N.
Published: November 2024

The occurrence of a rare uranium mineral, Ampangabeite, has been noticed for the first time in India, in two localities of the Bihar mica belt during a survey of the area for deposits of atomic minerals. It forms an accessory constituent of the mica pegmatites and is found as pockets of varying sizes and mostly confined to the weathered perthite zone bordering the quartz core. The mineral is identified as ampangabeite based on a study of its similarity in the mode of occurrence and chemical composition with the one described from the type locality of Ampangabe, Madagascar.
Vickers Micro Hardness of Magnetite, Maghemite and Hematite of a Titaniferous Vein Magnetite of Bonai, Orissa, and its Crypto-Textural Implications
Authors: Bhaumik Nirendra
Published: November 2024

Save for deviation due to the complex crypto-textures, the Vickers hardness (Hv) increases from magnetite, then to maghemite and considerably in hematite. The deviation of Vickers hardness from the comparative graph of a particular mineral species can be accounted for by the presence in the sample of other mineral species (not identifiable under 400 magnification) and also by the variations in crypto-textural dimensions.
The Archaean Provinces of India and their Comparison with those of Other Continental Shields
Authors: Rama Rao B.
Published: November 2024

Doubts still exist in regard to the precise correlation of the Archaean formations in the different regions of the Indian Shield, either with one another or with those of other continental shield areas. In this paper the information available at present on the composition, classification and correlation of the Archaean formations in the several pre-Cambrian shields of the world is briefly reviewed, and a broad generalised correlation based on their absolute ages is given. The rock formations older than the Cambrians, which range in their absolute ages from about 600 to 3,500 million years as shown by radiometric determinations, have been classified broadly into 8 age groups and standard names have been suggested for each of the groups.
Evolution of the Sharavati Drainage, Mysore State, S. India
Authors: Radhakrishna B. P.
Published: November 2024

The Sharavati river in Mysore, owes its importance as a potential source for the generation of hydroelectric power to the circumstance of river piracy. A swift flowing consequent stream, draining the western slopes of Western Ghats has pushed its way up the divide by rapid headward erosion and has captured the well graded mature drainage on the plateau surface at a higher base level. The origin of the Falls and the carving of the gorge below the Falls are the result of down-cutting and recession aided by the increased erosive power of the captured stream. The observed drainage anomalies are indicated to be the result of rejuvenation and uplift of the ancient peneplaned surface of the Peninsula in recent times. The Western Ghats represent the precipitous western edge of this uplifted plateau.
Recognition of Petrographic and Microfloral Assemblage Zones in Coal Seams
Authors: Navale G. K. B.
Published: November 2024

In a previous paper, the author has indicated the nature and importance of palynopetrographic approach of coals. To serve as an example of the results which may be obtained by the application of this method of study, a brief review of the work done by him in regard to two coal seams is given here.
Regional Structural Framework of the Lead-Zinc Deposits at Zawar, Rajasthan, India
Authors: Mookherjee Asoke
Published: November 2024

The structural elements in rocks around the Zawar area have developed during three successive stages. Movements at the earliest stage are registered by northerly plunging folds-upright to 'reclined'-with steeply dipping overturned axial-plane schistosity (S2) and attendant a- and b-lineations. Striations on bedding, tension cracks in fold-arches, and occasional disharmonic character of the minor folds point to a flexure-slip origin.

On these was superposed a generation of folds with contrasted style in profile and accompanying axial-plane cleavage (S8) and lineations.

Off-setting of all other S-planes by the mineralized shear planes, their discordant attitude, and the incongruency of their direction of slip (recorded on their surface by striations and mineral lineations) with the regional movement plan indicate that these were the youngest structure to develop.

Since the development of these structural elements (the mineralized shear zone) was broadly concurrent with metallization, these 'active' structural traps are believed to have been preferred to the earlier, relatively 'inactive' ones.

Future prospecting in this mining district should, therefore, be intensified in those dolomites where this youngest set of structures have developed.
Petro-Palynological Study of Churcha Seam, Sohagpur Coalfield (M.P.), India
Authors: Navale G. K. B. , Tiwari R. S.
Published: November 2024

Microscopic examination of polished pellets of Churcha coals reveals the nature of microfragmental constituents comprising mostly Durains. Petrological analysis has been made so as to assess the nature and distribution of different microconstituents. The miospore assemblage in this seam is a diversified one, consisting of 36 genera of triletes, monoletes, monosaccates, disaccates and others. The percentage frequencies of various genera have been determined. Petro-palynological constituents of this coal have been compared with those of other comparable beds in the Lower Gondwana of India.
Tertiary Sedimentation in the Andaman-Nicobar Geosyncline
Authors: Karunakaran C. , Roy K. K. , Saha S. S.
Published: November 2024

Andaman orthogeosyncline is continuous with Assam-Burma in the north and Indonesian geosyncline in the south. Andaman-Nicobar group of islands constituting the non-volcanic outer arc of the East Indian Orogen, has a more or less continuous history of Sedimentation throughout the Tertiary era commencing from sometime in the Upper Cretaceous right on to the Recent. The sedimentation gradually changed character with the tectonic development of the geosyncline through geologic time.

Euxinic sediments consisting of black pyritous shales with minor amount or dark impure limestone and gritty sandstones represent the earliest episode of geosynclinal sedimentation in the restricted basins formed by submarine ridges and valleys due to emplacement of ophiolites.

These ophiolites were subaerially denuded to some extent; and during Palaeocene-Lower Eocene, algal limestone and conglomerate and subsequently more finer fractions such as tuffaceous basic wacks and serpentinous and chloritic clay beds followed. Subsidence of the geosyncline which commenced with sedimentation of the Euxinic beds produced a uniform configuration of the geosyncline during Middle Eocene (Kirthar). Andaman flysch consisting of altetnatcly bedded graywackes, siltstone and grey illitic clay beds were deposited throughout the length and breadth in this regular geosynclinal basin till Upper Oligocene when a major orogenic movement overcame sedimentation.

Shallower basins formed within and in the outer margins of the rising emhryonic island arc were filled up during Lower Miocene with foraminifcrallimcstone and shale, and radiolarian and foraminiferal chalk beds.

Middle Miocene witnessed another major orogenic movement which brought out the present configuration of the island arc. Fossiliferous clays and limestones were deposited in peripheral basins during the Pliocene-Pleistocene which are partly raised during quite recent times.
The Koyna Earthquake
Authors: Gupte R. B.
Published: November 2024

A large part of Western Maharashtra experienced a severe earthquake on 11th December 1967. The earthquake caused great anxiety as the epicentre lay very close to the Koyna Dam of the vital Koyna Hydro Electric Project. Though the dam and other structures of the project suffered little damage, Koynanagar, the construction colony and Villages Within 25 km were devastated. The earthquake has puzzled all, as it took place in a region supposed to be stable; and It has become very difficult to offer a satisfactory explanation because of very imperfect knowledge of the geology of the earthquake area.
Layered Gabbro of the Igneous Complex of Phenai Mata, Gujarat State
Authors: Sukheswala R. N. , Sethna S. F.
Published: November 2024

Phenai Mata hill (Lat. 22°8'N., Long. 73°55'E.), believed to be a composite plug, is successively filled by basalt, gabbro, granophyre and nepheline syenite. The paper focusses attention on the layered character of the gabbro. Rhythmic layering is due to the repetition of thick anorthositic and gabbroic layers. Cryptic layering is marked by extreme variation in anorthite content of plagioclase. The differentiation trend is established by the chemical and petrographic studies of samples collected at regular intervals. Up to 600 feet the enrichment is towards both iron and alkali, after which the gabbro (tholeiitic) differentiates to a granitic residuum.