bluuebunny/crossref_metadata_2025 huggingface dataset:
Conditions, Problems of Human Development, His Health
Authors: Savotkin Nikolai Aleksandrovich
Published: June 2022

The paper deals with the development and health of a person as part of a living world and on the basis of its laws. Dependences of the level of development on the intensity and variety of activities are considered. The concepts of the environment, morality, and others are introduced, which make it possible to determine the role of morality in the development of man and mankind. It is shown that health is determined by the necessary and sufficient compliance with the environment. It is possible to save it with changes in the environment if the intensity of activity for the present time corresponds to the predicted rigidity of the environment of the future. The conditions for full health and life expectancy are determined. One of the conditions is the activity in the development zone. The connection between the development of mankind and its morality is established. The death of mankind during the development of a capitalist society, a consumer society, has been proven.
A Review on Green Synthesis of Silver Nanoparticles and its Role against
Cancer
Authors: Rani Neeraj , Singla Rajeev K. , Redhu Rakesh , Narwal Sonia , Sonia  , Bhatt Alok
Published: June 2022

Cancer is a fatal disease with a collection of related diseases in various body parts. The conventional therapies cannot show the desired results of treatment due to their imprecise targeting, deprived drug delivery, and side effects. Therefore, it is required to make the drug engineered so that it can target only cancerous cells and inhibit its growth and proliferation. Nanotechnology is a technology that can target and differentiate between cancerous cells and the body's normal cells. Silver itself is a good anticancer and antibacterial agent and employing it with phytochemicals with anticancer properties, and nanotechnology can give the best approach for the treatment. The synthe-sis of silver nanoparticles using plant extracts is an economical, energy-efficient, low-cost approach, and it doesn’t need any hazardous chemicals. In the present review, we discussed different methods of synthesis of silver nanoparticles using herbal extracts and their role against cancer therapy along with the synergistic role of silver and plant extracts against cancer in the formulation.
Viewer Behavior On Social Media: Viral Marketing of A Movie Trailer In Indonesia
Authors: Afifah Nur , Daud Ilzar , Mulyadina Morella
Published: June 2022

A trailer is a brief description of a film and provides a 1 to 3 minute cinematic experience that displays images from the film to influence consumer behavior. This research was conducted to propose a conceptual model regarding affective, cognitive, and environmental responses to viral marketing, which are moderated by audience behavior, for the movie trailer of “Spiderman: Far from Home.” The film was released in July 2019 by Marvel Cinematic Universe (MCU). This study adopted the wheel of consumer analysis to bridge the research gap. An online survey was forwarded to 200 respondents using structured questionnaires through social media sites, such as Line, WhatsApp, Facebook, and e-mail. The data were then analyzed using structural equation modeling (SEM). The results showed that the audience’s affective, cognitive, and environmental responses significantly influenced viral marketing. The results further indicated that the audience’s behavior was not a moderating variable, as the significance level was less than 0.05. The results can contribute to determining social media marketing strategies for promoting film trailers that are beneficial for companies, especially in Indonesia. Therefore, the companies can grow and become more competitive in the film industry. Although this study discusses viral marketing in the film industry, the results can also contribute to other industries, in order to increase the popularity of their products.
Application of HEC-HMS model and satellite precipitation products to restore runoff in Laigiang river basin in Vietnam
Authors: Tu Ngo Anh , Xuan Nguyen Huu , Tuong Vi Nguyen Thi , Le Phan Thai
Published: June 2022

The Laigiang river basin in the South Central Coast of Vietnam plays an important role in the socio-economic development of Binhdinh Province. In recent decades, the region has experienced commonly flooding in vast areas. This research aims to simulate event-based rainfall-runoff modelling, a historical flood event in December 2016, by applying the HEC-HMS model and rainfall data from CHIRPS. The CHIRPS data is an acceptable potential data input of the hydrology model. These have been confirmed through reliable validation indexes: The peak flood flow rate of 2,542.6 m3/s corresponds to the flood frequency of 5%; NSE with the value at 0.95; R2 coefficient reached 0.87; PBIAS being around 0.45, and PFC being at 0.89. It shows better performance in the rainy season than in the dry season. Inclusive, the CHIRPS rainfall data set and the HEC model could be used for some operational purposes in weather forecasting, especially for flood warnings in river basins in the South Central Coast, Vietnam.
Masked Face Recognition and Temperature Monitoring Systems for Airplane Passenger Using Sensor Fusion
Authors: Feni Isdaryani  , Noor Cholis Basjaruddin  , Aldi Lugina
Published: June 2022

Transportation is currently an unavoidable necessity. However, the COVID-19 pandemic has impacted all lines of industry, including the Indonesian aviation transportation industry. Technology is one of the solutions to deal with these problems. The monitoring system of masked face recognition and body temperature detection for the check-in process of passengers at the airport is aimed to be developed in this research. The contribution of this research is that the system can distinguish the type of face mask used. Therefore, this monitoring system classified only medical masks and N95/KN95 respirator masks as ‘Good Masked’. IP camera and thermal camera are used to identify a masked face and body temperature, respectively. The sensor fusion method was used for decision-making on passengers whether they can be departed or not. The decision was taken based on the measured body temperature, the use of standardized face masks, and the face recognition of the airport passengers. Convolutional neural network (CNN) method was used for face and face mask recognition. The CNN model training was conducted four times according to the four proposed scenarios. The CNN model that has been trained can distinguish a masked face and a face without a mask. The best results were obtained in the fourth scenario with the comparison of the training dataset to the testing dataset was 9:1 and the epoch was 500 times. The basic deep learning model used for face detection was the single shot multibox detector (SSD) using the ResNet-10 architecture. Meanwhile, the CNN method with the MobileNetV2 architecture was used to detect the use of masks. The accuracy of the CNN model for face recognition and mask recognition was 100%. All check-in monitoring and verification process data were displayed on the web application which was built on the localhost.
Optimasi Sistem Pembangkit Listrik Tenaga Hybrid di Pulau Enggano
Authors: Dyah Ayu Kartika Sari  , Fransisco Danang Wijaya  , Husni Rois Ali
Published: June 2022

Pulau Enggano merupakan salah satu wilayah terluar yang menggunakan pembangkit listrik tenaga diesel (PLTD) sebagai sumber energi listriknya. PLTD yang mulai beroperasi sejak tahun 2017 ini terdiri atas tiga unit mesin pembangkit yang mampu menghasilkan daya sebesar 730 kW, dengan total pelanggan sebanyak 1.050 pelanggan dan kebutuhan energi listrik sebesar 1.097.883 kWh/tahun. Meskipun pembangkit listrik telah tersedia, pada kenyataannya permasalahan ketenagalistrikan masih menjadi masalah dasar yang belum terselesaikan di pulau ini. Rata-rata pemakaian bahan bakar minyak (BBM) untuk mengoperasikan PLTD adalah 21 ton/bulan atau Rp582.757.000,00 per bulan dengan asumsi harga BBM adalah Rp9.800,00 per liter. Tingginya biaya operasional mengakibatkan listrik hanya dipasok selama enam belas jam per hari. Pemanfaatan PLTD juga menghasilkan emisi karbon dioksida (CO2) yang sangat tinggi. Hal ini tidak sejalan dengan komitmen pemerintah untuk bertransisi menuju net zero emission pada tahun 2060. Pemanfaatan energi baru terbarukan (EBT) yang ditargetkan sebesar 23% pada tahun 2025 nyatanya masih belum maksimal. Makalah ini bertujuan untuk menemukan konfigurasi pembangkit tenaga hybrid yang optimal di Pulau Enggano dari segi teknis dan kelayakan ekonomi. Kelayakan ekonomi ditinjau menggunakan pendekatan net present cost (NPC) dan cost of economic (COE). Selain itu, dilakukan juga analisis keberlanjutan dari aspek lingkungan. Dari penelitian ini, didapatkan konfigurasi yang paling optimal berdasarkan biaya sistem terendah, yaitu konfigurasi 2 skenario 1, yang terdiri atas photovoltaic (PV) 1.005 kW, diesel 250 kW, dan baterai 594 unit. Konfigurasi ini dapat memproduksi listrik sebesar 1.576.115 kWh/tahun dengan nilai NPC mencapai Rp31,7 miliar rupiah dan nilai COE sebesar Rp1.998,75 per kWh. Konfigurasi ini juga memiliki keberlanjutan lingkungan yang baik karena memiliki nilai renewable fraction sebesar 91%.
Women Detectives in Detective Fiction: A Formula Analysis on Dublin Murder Squad Series
Authors: Fadhila Alya Khoirunnisa , Adi Ida Rochani
Published: June 2022

This paper studies the formulation of two women detectives in Tana French’s work, Cassie Maddox and Antoinette Conway, in the Dublin Murder Squad Series by exploring the hard-boiled fiction conventions which underlie the formulation of Tana French’s two female detectives. The objective of this study is to determine how French innovates the hard-boiled fiction conventions in the formation of her women detective characters, Cassie Maddox and Antoinette Conway. By employing formula analysis as theorized by John G. Cawelti (1976), the results of this study show that French innovates the hard-boiled formula in four aspects. First, French innovates the hard-boiled formula by expanding the concept of marginality from economic class to gender and race. The second innovation is the substitution of the hard-boiled convention which emphasizes on masculine toughness with resistance to patriarchal control. Third, French re-established the relationship between the detective and the character femme fatale. Their similarity of female experiences and perspective with the femme fatale makes these women detectives not only reveal the femme fatale as a murderer, but also the motives and scenarios behind their acts. Finally, French also innovates the antithetical nature of the hard-boiled detective’s presentation by offering a ‘feminine’ path to justice. These observations show that French’s innovations on hard-boiled conventions on her women detectives are the extensions of the women investigators in the antecedent feminist revisions of the hard-boiled stories which are heavily influenced by the second-wave feminist values. However, Tana French also inserts her own commentary on the new variants of female character shaped by the new post-feminist discourse which separates her women detectives from those in the antecedent feminist hard-boiled revision series.
Sintomatología ansiosa en estudiantes de universidades dominicanas durante COVID-19
Authors: Frías-Veras Melanie , Guzmán Lazala Teresa Del Carmen , Sánchez-Vincitore Laura Virginia
Published: June 2022

Este estudio tiene la finalidad de analizar la sintomatología ansiosa de 239 estudiantes en universidades de República Dominicana durante el cierre de las instituciones educativas por la pandemia de COVID-19 en el mes de octubre de 2020. Se utilizó un cuestionario sociodemográfico y la adaptación española del Inventario de Ansiedad de Beck. Esta investigación es de tipo cuantitativo, transversal y con un alcance descriptivo-correlacional. Se reclutó a los participantes a través de un muestreo por bola de nieve. Se analizaron los datos con el fin de estudiar diferencias por sexo, carrera y edad. Se encontraron niveles de ansiedad de moderados a altos en la muestra estudiada. Los hallazgos fueron significativos para los síntomas de ansiedad, diferenciados por sexo, y no se encontraron correlaciones estadísticamente significativas entre sintomatología ansiosa y edad. Con base en estos descubrimientos, se enuncian algunas medidas que pueden ser implementadas por las autoridades institucionales orientadas a estudiantes universitarios.
Incidence of Autoimmune Arthritis Disease Flare Following SARS-CoV-2 Vaccination and its Association with Concurrent NSAID Use
Authors: Bailey Rachael , Paddison Clint , Bharti Vidhi
Published: June 2022

Background: This study aims to analyze the association between COVID-19 vaccination and an inflammatory arthritis reaction in autoimmune arthritis patients.
Methods: A survey was completed by participants with inflammatory arthritis between August 17 and 18, 2021. Survey participants (n = 1348) responded to questions about their diagnosis, the length of their diagnosis, current medication, brand of vaccine received, incidence of inflammatory arthritis symptoms after COVID-19 vaccination, and how long the symptoms persisted. Participants were also asked to report any other notable side effects experienced after vaccination.
Results: Participants reported a diagnosis of rheumatoid arthritis (83.9%), psoriatic arthritis (6.5%), ankylosing spondylitis (2.5%), fibromyalgia (1.1%), lupus (0.5%), or other inflammatory arthritides (5.5%). Most participants reported having their condition for 5–10 years (25.3%), with only 4.6% having been diagnosed within the last year. Current use of disease-modifying antirheumatic drugs (DMARDs) was reported by 36.8% of participants, while 15% and 7.7% reported taking a biologic drug/infusion or non-steroidal anti-inflammatory drugs (NSAIDs), respectively, and 22.8% indicated that they were taking no medication. Types of COVID-19 vaccine reported were Pfizer-BioNTech (51.9%), Oxford AstraZeneca (24.2%), Moderna (19.2%), Janssen/Johnson & Johnson (3.2%), and Sinopharm (1.5%). Following vaccination, 21% of participants reported experiencing inflammatory arthritis symptoms, with 14% indicating a possible mild flare (“perhaps a little”). These symptoms were reported to be ongoing by 40.7% of participants. Statistical analysis revealed that vaccine brand and diagnosis had no significant effect on the incidence of self-reported post-vaccination inflammatory arthritis symptoms. Participants currently taking NSAIDs were significantly more likely to report a vaccine-induced inflammatory arthritis reaction; however, it remains unclear if this was due to concurrent NSAID use or because of the likely increased disease activity in participants taking NSAIDs.
Conclusion: In support of other published studies, our data indicate a low incidence of COVID-19 vaccine-induced inflammatory arthritis reaction in autoimmune arthritis patients. Patients currently taking NSAIDs may have an increased risk of experiencing inflammatory arthritis symptoms following their COVID-19 vaccination.
Improved Outcomes in Multiple Sclerosis Using a Lifestyle Medicine Approach: A Case Study and Patient Perspective
Authors: Bansal Shipra , Pendlebury Gehan , Oro Peter
Published: June 2022

Introduction: Although numerous pharmaceutical agents have been developed to treat multiple sclerosis (MS)and have been shown to improve outcomes significantly, the use of lifestyle therapies has not been well understood or implemented.
Purpose: The current case study describes the course of a 48-year-old patient with relapsing-remitting MS who chose to use lifestyle measures to manage her condition.
Interventions and outcomes: The patient tried several medications without marked improvement. After 4 years, she decided she no longer wanted to risk medication side effects while still having regular relapses. She adopted a plant-based diet, started exercising as tolerated, and worked on improving her mental health through mindfulness and spiritual practices. During the 12 years after these changes, the patient experienced 5 exacerbations in total. In 2021, magnetic resonance imaging scans were compared with pre-lifestyle change scans; there was some increase in the size and number of T2 bright lesions but no significant lesion enhancement. The patient currently enjoys a quality of life equal to someone without MS.
Conclusions: Although pharmaceuticals are the mainstay of MS therapy, a full lifestyle approach in addition to, or instead of, traditional therapies warrant increased attention, especially in patients who are unable to tolerate medication side effects and are committed to making lifestyle changes.
Assistência farmacêutica no componente especializado: um estudo de análise lógica
Authors: Couto Damiana de Almeida , Amaral Bruno Andrade , Prado Nília Maria de Brito Lima
Published: June 2022

Este estudo objetivou realizar uma análise lógica das atividades de assistência farmacêutica em um serviço de referência, vinculado ao componente especializado em um município do semiárido baiano, com o intuito de mapear os processos e atividades implementados para assegurar a integralidade das práticas definidas pelo Ministério da Saúde. A pesquisa teve natureza qualitativa, avaliativa e descritiva e foi realizada em duas etapas: uma análise documental que derivou do modelo teórico; e uma aplicação de questionários aos farmacêuticos que atuaram ou atuam no serviço do componente especializado. Foi indicada uma imagem objetiva ideal; as atividades técnico-gerenciais estavam adequadas ao âmbito local. Contudo, foi descoberto que as atividades técnico-assistenciais estavam restritas à dispensação dos medicamentos conforme os protocolos clínicos. Constatou-se que as atividades técnico-gerenciais são realizadas como preconizadas e as técnico-assistenciais divergem daquilo recomendado pelas diretrizes políticas.
Judicializing Foreign Affairs: The Canada-Saudi Arms Deal and the Implications of Transnational Tort Litigation
Authors: Ahmad Hassan M.
Published: June 2022

In the recent past, the ability to challenge Canadian government action with foreign relations elements has spilled over from administrative law into tort law. At the same time, tort actions against multinational corporations for human rights violations abroad have also seen a surge in Canadian courts, culminating in the Supreme Court’s recent decision in Nevsun Resources Ltd. v. Araya. This article addresses some doctrinal elements of a potential transnational tort claim against the Canadian government and a Canadian arms manufacturer pursuant to human rights violations arising from the 2014 Canada-Saudi Arms Deal [CSAD]. It also explores consequential effects that Canada’s burgeoning transnational tort laws can have on Canada-Saudi relations as well as the Canadian defence industry. Overall, this article uses the CSAD as one real-life scenario in which private law litigation can have broader effects on a country’s foreign relations and domestic economy. In this instance, the judiciary’s power to exact extra-judicial consequences illustrates how tort litigation can curtail the behaviour of governmental and commercial actors.
PELINDUNGAN HAK-HAK MASYARAKAT DALAM RENCANA TATA RUANG WILAYAH DI KOTA JAMBI
Authors: Andika M. , Claresa Yolanda , Rahmi Elita
Published: June 2022

Penelitian ini bertujuan untuk mengungkap, mengkaji, dan memahami kebijakan Rencana Tata Ruang Wilayah ditinjau dari aspek normatif, lebih khusus mengkaji tentang perlindungan hukum hak-hak dan peran serta masyarakat. Penelitian ini dilakukan untuk menganalisis secara normatif kebijakan dan strategis pola pemanfaatan ruang wilayah Kota Jambi berdasarkan Perda RTRW Nomor 10 Tahun 2013, dan untuk menganalisis perlindungan hukum dan keberpihakan terhadap hak-hak masyarakat sebagai salah satu pemangku kepentingan. Metode Pendekatan yang digunakan adalah metode pendekatan normatif.Jenis pendekatan yang dipergunakan adalah pendekatan perundang-undangan (statute approach), pendekatan konsep (conceptual approach), pendekatan analitis (analytical approach), dan pendekatan historis (historical approach).  Hasil penelitian setelah dianalisis secara normatif dan kualitatif, menunjukkan bahwa secara konseptual hak-hak individu dan masyarakat telah diatur dan dilindungi oleh Konstitusi Negara, yaitu UUD 1945 maupun oleh berbagai peraturan perundang-undangan, terutama yang mengatur tentang Penataan Ruang (Undang-undang Nomor 26 Tahun 2007, Peraturan Pemerintah Nomor 15 Tahun 2010, dan Peraturan Pemerintah Nomor 68 Tahun 2010). Selain itu juga Undang-undang Nomor 12 Tahun 2011 tentang Pembentukan Peraturan Perundang-undangan bahwa setiap pembentukan peraturan perundang-undangan harus melibatkan masyarakat. Demikian pula halnya dengan Perda RTRW Nomor 10 Tahun 2013 telah mengatur dan melindungi secara jelas hak dan kewajiban masyarakat, akan tetapi keterlibatan masyarakat dalam penyusunan RTRW  hanya sebatas konsultasi publik saja. Padahal bentuk partisipasi masyarakat menurut Undang-undang dan Peraturan Pemerintah bukan hanya sebatas konsultasi publik akan tetapi peran serta  dalam menyusun dan merencanakan penataan ruang tersebut. Oleh karena itu, Pemerintah Kota Jambi dalam rangka memberikan perlindungan hukum hak-hak masyarakat sebagai salah satu pemangku kepentingan dengan baik, maka perlunya melakukan peninjauan kembali, dan keikutsertaan masyarakat harus diutamakan.
PERATURAN TATA RUANG DALAM MEMBERIKAN IZIN MENDIRIKAN BANGUNAN PADA RUMAH IBADAH
Authors: Theresia Simanullang Berty , Tobing Maria , Helmi Helmi
Published: June 2022

The Indonesian state is obliged to facilitate the people living within its territory so that they can live harmoniously side by side. Pancasila as the basis of the state strives to create harmony in the population including harmony in religion. Pancasila has been agreed to be the basis of the state and functions to protect religious plurality in Indonesia, one of which is in establishing houses of worship as stated in the 1945 Constitution Article 29 paragraph (2) which reads: "The state guarantees the independence of every citizen to embrace their respective religions and to worship according to that religion and belief ”. Therefore, houses of worship and the implementation of religious worship are important and fundamental matters for every religious community guaranteed by the state. But in reality, there are still many houses of worship that are not built in accordance with existing regulations in Indonesia, causing many conflicts and conflicts in the community.
Pendaftaran Merek Dagang Produk Sirup Kayu Manis di Kabupaten Kerinci
Authors: Tayosa Prayoga , Naili Hidayah Lili
Published: June 2022

The purpose of this thesis is to find out and analyze what are the factors that cause cinnamon syrup entrepreneurs in the village of Siulak Deras Mudik Gunung Kerinci Subdistrict Kerinci Regency does not register their trademarks and to find out and analyze what the legal consequences of cinnamon syrup entrepreneurs in Siulak Deras Mudik village does not register its trademark. This type of research is empirical juridical. Based on the results of the research, the causal factor for not registering trademarks by Cinnamon Syrup entrepreneurs is the lack of understanding of trademarks, the cost of trademark registration is quite expensive. Furthermore, due to a business not registering its trademark viz. There is no protection of the owner of the trademark rights from acts of piracy, counterfeiting and use of his trademark without permission from the trademark owner. other parties may carelessly use brands that have not been registered for their own benefit. the brand owner will not be safe, so in this case the intellectual ideas that he has to make new innovations for his work become useless because people easily imitate these ideas. If there are legal issues regarding this cinnamon syrup brand then it cannot be resolved through legal channels. Brand which was as a differentiating power is now no longer a differentiating power in trading activities, because everyone can use the brand in a business and competition in the global market.

Keywords:   brand; registration.

 

Abstrak

Tujuan penulisan skripsi ini adalah untuk mengetahui dan menganalisa apa saja yang menjadi Faktor penyebab pengusaha sirup kayu manis di Desa Siulak deras Mudik Kecamatan Gunung Kerinci Kabupaten Kerinci tidak mendaftarkan merek dagangnya dan untuk mengetahui dan menganalisa apa akibat hukum pengusaha sirup kayu manis di desa siulak deras mudik tidak mendaftarkan merek dagangnya. Jenis penelitian adalah yuridis empiris. Berdasarkan Hasil penelitian faktor penyebab tidak didaftarkannya merek dagang oleh pengusaha Sirup kayu manis adalah kurangnya pemahaman mengenai merek, biaya pendaftaran merek yang cukup mahal. Selanjutnya akibat suatu usaha tidak mendaftarkan mereknya yaitu. Tidak ada perlindungi pemilik hak atas merek dari tindakan pembajakan, pemalsuan, dan penggunaan merek miliknya tanpa izin dari pemilik merek. pihak lain bisa sembarangan menggunakan merek yang belum terdaftar untuk keuntungan sendiri. pemilik merek tidak akan aman, sehingga dalam hal ini ide-ide intelektual yang dia punya untuk membuat inovasi baru untuk karyanya menjadi tidak berguna karena orang dengan mudahnya meniru ide-ide tersebut.jika ada persoalan hukum menganai merek sirup kayu manis ini maka tidak bisa di selesaikan melalui jalur hukum.Merek yang tadi sebagai daya pembeda sekarang tidak lagi sebagi daya pembeda dalam kegiatan perdagangan, karena setiap orang dapat menggunakan merek tersebut dalam suatu bisnis dan persaingan di pasar global.

Kata-kata kunci : pendaftaran; merek.
Praktik dan Disparitas Putusan Hakim Dalam Menetapkan Force Majeure di Indonesia
Authors: Irfan Hilmy Muhammad , Yusuf Muhammad Fadhali
Published: June 2022

Force majeure becomes one of debtor's objections when there is a default in an agreement. In determining the circumstances included in the force majeure criteria, the judge considers the clause of the agreement and the effect that results from a situation on the fulfillment of the achievement. Every incident may not be said to be a force majeure because it sees how much influence factors that influence achievement of achievement. Force majeure is determined because of several things based on the cause, nature, subject, and scope. Juridical provisions related to force majeure in Indonesia are contained in the Civil Code, Laws and Jurisprudence. This paper will discuss the practice of determining force majeure in Indonesia, which refers to a judge's decision that sets a situation as a force majeure. The purpose of this paper is to find out the judge's analysis in rejecting or establishing a forceful situation. The research method used in this paper is normative juridical or also called doctrinal law research. The author refers and reviews the jurisprudence that discusses force majeure to find out the differences in analysis caused by differences in case backgrounds.
 
Abstrak
Force majeure menjadi salah satu tangkisan debitur ketika terjadi wanprestasi dalam suatu perjanjian. Dalam menentukan keadaan yang masuk dalam kriteria force majeure hakim mempertimbangkan klausula perjanjian serta pengaruh yang dihasilkan akibat suatu keadaan terhadap pemenuhan prestasi. Setiap kejadian belum tentu dapat dikatakan sebagai force majeure karena melihat seberapa besar faktor pengaruh yang mempengaruhi pemenuhan prestasi. Force majeure ditetapkan karena beberapa hal berdasarkan penyebabnya, sifatnya, subjeknya, dan ruang lingkupnya. Ketentuan yuridis terkait force majeure di Indonesia terdapat dalam KUH Perdata, Undang-Undang, dan yurisprudensi. Tulisan ini akan membahas praktik penetapan force majeure di Indonesia yang mengacu pada putusan hakim yang menetapkan suatu keadaan sebagai force majeure. Tujuan penulisan ini adalah untuk mengetahui analisis hakim dalam menolak atau menetapkan suatu keadaan memaksa. Metode penelitian yang digunakan dalam penulisan ini adalah yuridis normatif atau disebut juga penelitian hukum doktrinal. Penulis mengacu dan mengulas pada yurisprudensi yang membahas mengenai force majeure untuk mengetahui perbedaan analisis yang disebabkan karena perbedaan latar belakang perkara.
Perjanjian Antara Dinas Tanaman Pangan Hortikultura dan Peternakan Provinsi Jambi Dengan CV. Kharisma Bintang Mandiri Dalam Pengadaan Ternak Sapi Potong
Authors: Yahya Fachry , Hosen M. , Alissa Evalina
Published: June 2022

This study aims 1) to find out and analyze the implementation of the rights and obligations of the parties in the implementation of the agreement between the Horticultural Food and Livestock Service Office of Jambi Province in the Procurement of Beef Cattle, and 2) the constraints faced in the implementation of the agreement. The research method used is empirical juridical. The results showed that 1) the implementation of an agreement for procurement of beef cattle 78 volumes of beef cattle culture development activities between the Horticultural Food and Livestock Service Office of Jambi Province and CV. Charisma Bintang Mandiri was not in accordance with the contents of the agreement because CV. Charisma Bintang Mandiri did not carry out its full obligations which can be detrimental to both parties, such as delays in completion of work 2) The number of cows imported is not in accordance with what was promised causing losses to the Horticultural Food and Animal Husbandry Office of Jambi Province. Therefore CV. Charisma Bintang Mandiri is in default and must compensate in accordance with the existing agreement.
Keywords: Agreement, Procurement of Beef Cattle
 
Abstrak
Penelitian ini bertujuan 1) untuk mengetahui dan menganalisis pelaksanaan hak dan kewajiban para pihak dalam pelaksanaan perjanjian antara Dinas Tanaman Pangan Hortikultura dan Peternakan Provinsi Jambi Dalam Pengadaan Ternak Sapi Potong, dan 2)Kendala-kendala yang dihadapi dalam pelaksanaan perjanjian tersebut. Metode penelitian yang digunakan adalah yuridis empiris. Hasil penelitian menunjukan bahwa 1)pelaksanaan perjanjian pengadaan ternak sapi potong volume 78 ekor kegiatan pengembangan budidaya sapi potong antara Dinas Tanaman Pangan Hortikultura dan Peternakan Provinsi Jambi dengan CV.Kharisma Bintang Mandiri tidak sesuai dengan isi perjanjian karena CV.Kharisma Bintang Mandiri tidak melaksanakan kewajiban sepenuhnya yang dapat merugikan kedua belah pihak, seperti  keterlambatan penyelesaian pekerjaan 2)Sapi yang didatangkan jumlahnya tidak sesuai dengan yang apa yang diperjanjikan yang menyebabkan kerugian bagi Dinas Tanaman Pangan Hortikultura dan Peternakan Provinsi Jambi. Karena itu CV.Kharisma Bintang Mandiri melakukan wanprestasi dan harus mengganti rugi sesuai dengan kesepakatan yang ada.
Kata kunci: Perjanjian, Pengadaan Sapi Potong
Penyelesaian Sengketa Konsumen Melalui Pembentukan Badan Penyelesaian Sengketa Konsumen di Kota Jambi
Authors: Marbun Novalia , Pahlefi Pahlefi
Published: June 2022

The writing of this thesis examines the resolution of consumer disputes through the establishment of the Consumer Dispute Resolution Agency (BPSK) in the city of Jambi. The purpose of writing, knowing and analyzing consumer dispute resolution through BPSK so that it becomes urgent in the city of Jambi. Formulation of the problem regarding the form of consumer dispute resolution in the city of Jambi and the importance of non-litigation resolution, namely through BPSK so that it becomes urgent in the city of Jambi. The research method used is empirical research with descriptive qualitative analysis research specifications. The findings in this thesis, first of the twenty-two consumer complaints to the Indonesian Consumers Foundation (YLKI), ten cases of consumer disputes that entered the BPSK district / city of Bungo, five cases of consumer disputes that were submitted to the BPSK regency / city of Sarolangun. It appears that consumer complaint disputes will continue because the relationship between business actors and consumers is intertwined with one another. Second, the process of consumer dispute resolution assisted by YLKI is limited and does not have the final power as BPSK. Then, the government's attention is needed as an effort to improve the welfare of the community in helping people resolve consumer disputes by facilitating BPSK as a special body based on the mandate of consumer protection law.
Abstrak
Penulisan skripsi ini mengkaji mengenai penyelesaian sengketa konsumen melalui pembentukan Badan Penyelesaian Sengketa Konsumen (BPSK) di kota jambi. Tujuan penulisan, mengetahui dan menganalisis penyelesaian sengketa konsumen melalui BPSK sehingga menjadi urgen di kota jambi. Rumusan masalah mengenai bentuk penyelesaian sengketa konsumen di kota jambi dan pentingnya penyelesaian non litigasi yaitu melalui BPSK sehingga menjadi urgen di kota jambi. Metode penelitian yang digunakan penelitian empiris dengan spesifikasi penelitian deskriptif analisis kualitatif. Temuan dalam skripsi ini, pertama dari dua puluh dua pengaduan konsumen kepada Yayasan Lembaga Konsumen Indonesia (YLKI), sepuluh kasus sengketa konsumen yang masuk ke BPSK kabupaten/kota bungo, lima kasus sengketa konsumen yang masuk ke BPSK kabupaten/kota sarolangun. Terlihat bahwa sengketa pengaduan konsumen akan terus berlangsung karena hubungan antara pelaku usaha dan konsumen yang saling terikat satu sama lain. Kedua, adapun proses penyelesaian sengketa konsumen yang dibantu oleh YLKI terbatas dan tidak mempunyai kekuatan final seperti halnya BPSK. Kemudian, diperlukan perhatian dari pemerintah sebagai upaya mensejahterakan masyarakat dalam membantu masyarakat menyelesaikan sengketa konsumen dengan memfasilitasi BPSK sebagai badan khusus berdasarkan amanat undang – undang perlindungan konsumen.
SWOT Analysis by Realizing Cluster Analysis to Reducing Risk of Hospitality Business Losses in Central Sulawesi
Authors: Jalil Moh. Said , Mufitatul Annisa  , Selvia Anggun Wahyuni  , Iut Tri Utami  , Iman Setiawan
Published: June 2022

Hotels are a form of building or accommodation business that provides lodging services, as well as other facilities where all services are for the general public. Reducing the risk of the hotel business can be done by building strategies or actions that are continuously carried out based on the perspective of what is expected by customers in the future. This study uses a SWOT analysis by realizing the use of cluster analysis to provide an overview of the location and reduce the risk of loss in the hotel business in Central Sulawesi Province. From the internal and external results of SWOT in the hotel business, it can be concluded that investors must improve their strategy by prioritizing geographical location in building hotels by calculating that disasters can occur at any time.
Taxonomic status ot the earthworm species Metaphire saigonensis (Omodeo, 1956) (Clitellata: Megascolecidae)
Authors: Nguyen Tung Thanh , Thai Dung Thi-Ngoc , Trang Y Thi-Nhu , Duong Vy Thuy
Published: June 2022

The species M. saigonensis (Omodeo, 1956) was re-accessed based on a comparison between its original description and different variations of M. bahli and M. peguana. A total of 65 specimens of M. bahli and 69 specimens of M. peguana collected from various parts in southern Vietnam were used to examine. As a result, M. bahli has two different morphs (with and without concave male region). M. peguana has two subspecies, but rather stable in morphology. M. saigonensis is totally different from M. peguana in closer ventral distance between male pores, spermathecal pores, but it is very similar to the morph 2 of M. bahli. Therefore, it is concluded that M. saigonensis is a junior synonym of M. bahli.
Forecasting of stock prices on the Indonesian Sharia Stock Index (ISSI) using backpropogation artificial neural network
Authors: Pratamasyari Dede Arseyani
Published: June 2022

Forecasting is a method for estimating a value in the future by looking at data in the past. In this study, the author will discuss the results of forecasting the price of the Islamic stock index using a backpropogation artificial neural network. The results show that the forecasting value of the stock closing price at ISSI for the next 1 period April 2018 is an average of 192,6842. After getting the forecast value, then it is compared with the actual average data, which is 185.4748. the amount of error generated greatly affects the number of inputs and the selection of the right network architecture pattern.

 

Keywords: Prediction, Backpropogation, ISSI
Determination of peroxide by spectrophotometry in waste cooking oil using adsorbents from banana midrib and water hyacinth
Authors: Yazid Edy Agustian , Wafi Abdul , Maryaningsih Siti
Published: June 2022

Waste cooking oil is cooking oil that has been used to fry food ingredients repeatedly. Cooking oil heated at high temperatures will be damaged to produce peroxide compounds that accelerate the process of developing a rancid odor, reducing the quality of the oil and the nutritional value of fried foods. The research was conducted by the spectrophotometric method using a wavelength of 200-300 nm. Based on the results of the study, the addition of 0.5 g, 1.0 g, 1.5 g and 2.0 g of banana midrib adsorbents obtained peroxide concentrations of 0.031%, 0.033%, 0.034%, and 0.034% respectively. The addition of water hyacinth adsorbent successively obtained 0.035%; 0.038%, 0.039%, and 0.038%. The largest percentage decrease was found in the addition of banana midrib adsorbents, namely 38% and water hyacinth 30%. From the independent T-test statistical test, it was obtained that p<0.05 was significant, so it can be concluded that there was a decrease in peroxide concentration in the addition of banana midrib and water hyacinth adsorbents to waste cooking oil

Keywords: Adsorbent, Waste cooking oil, Peroxide, Banana midrib, water hyacinth.
Toxic epidermal necrosis following Sinopharm COVID-19 vaccine (BBIBP-CorV): A case report and literature review
Authors: Shakoei Safoura , hadizadeh Alireza
Published: June 2022

This study reports a patient developing TEN after the first dose of
(BBIBP-CorV). He developed numerous purpuric and dusky patches with
flaccid bullae and areas of epidermal detachment covered more than 30%
of the body area within 6 days. After treatment with dexamethasone and
cyclosporin, he recovered within 14 days.
Analysis and Experimental Study of DFR Values for Aircraft Wing-fuselage Joint Structure
Authors: Sui Lijun , Sun Youchao
Published: June 2022

Previous studies obtained the static and fatigue strength
characteristics of the wing-fuselage joint structure by finite element
analysis. In this paper, for the wing-fuselage tie rod and its
connecting joint, the stress distribution at the detail design points
and the calculated Detail Fatigue Rating (DFR) values were obtained by
finite element analysis, and the test part design was simplified; the
test life data were obtained by fatigue tests of the wing-fuselage tie
rod and its connecting joint, and the test DFR values were obtained. The
results show that the stress level of the simplified structure differs
little from that of the real structure, so the simplified structure can
be used for the test instead of the real structure; in the test, the
contact area of the wing lug structure is the initial area for fatigue
cracks generation. The DFR values obtained from the test are larger than
those calculated, which indicates that the calculated results are on the
conservative and safe side.
SHR2285, the first selectively oral FXIa inhibitor in China: Safety, tolerability, pharmacokinetics and pharmacodynamics combined with aspirin, clopidogrel or ticagrelor
Authors: Ma Tingting , Dong Yanli , Huang Lei , Yang Yuanxun , Geng Yan , Fei Fei , Jin Yun , Yang Zeyu , Xie Pinhao , Zhao Yu , Lin Hui , Ju Xitong , Sun Runbin , Li Juan
Published: June 2022

Aim: To evaluate the safety, tolerability, pharmacokinetics and
pharmacodynamics of SHR2285, the first oral coagulation factor XIa
(FXIa) inhibitor developed in China in combination with aspirin,
clopidogrel or ticagrelor in healthy subjects. Methods: This study was a
single-center, randomized, double-blind, placebo-controlled (only
SHR2285) design. A total of 52 healthy subjects, 29 male and 23 female,
were enrolled in this study. The subjects were divided into three
groups: A, B and C, 16 subjects in group A (aspirin+clopidogrel+placebo
or SHR2285 200mg bid (1:3)), 16 subjects in group B
(aspirin+clopidogrel+placebo or SHR2285 300mg bid (1:3)) and 20 subjects
in group C (aspirin+ticagrelor+placebo or SHR2285 300mg bid (2:3)),
respectively. All groups were administered orally for 6 consecutive
days. Results: 1. SHR2285 was well tolerated, and all adverse events
were mild. There was no evidence of an increased risk of bleeding. 2.
After 6 days of twice-daily administration, SHR2285 could reach a steady
state. The half-life of SHR2285 was 13.9h, 14.5h and 13.8h respectively.
3. SHR2285 markedly inhibited FXI: C and prolonged APTT. The maximum
inhibition rates of FXI: C in the three groups were 84.8%, 89.3% and
92.2% and the maximum prolongation time of APTT was 2.08-, 2.36-, and
2.26-fold, respectively. 4. The combination of aspirin, clopidogrel or
ticagrelor had limited effect on the AUC of SHR2285. Conclusion: These
data suggest that SHR2285, a potential oral FXIa inhibitor, is expected
to become a novel, safe and effective anticoagulant.
The progress and prospect of sentinel lymph node mapping in endometrial carcinoma
Authors: Chen qianrun , Ruan Danhua , Shi Jiayan , Du Dongru , Bian ce
Published: June 2022

Sentinel lymph node (SLN) refers to the initial site of the lymphatic
drainage from a primary tumor area. Accordingly, sentinel lymph node
mapping (SLNM) has been brought up and widely applied to cancer therapy
for its illuminating role in clinical lymph node resection. Furthermore,
sufficient information to guide surgical pathological staging and
adjuvant treatment in endometrial cancer can be rendered by SLNM, hence
minimizing surgery injury and reducing the incidence of complications.
This review aims to systematically summarize the advances and
application prospects of SLNM in endometrial cancer, with an expectation
of furnishing reference for the clinical application.
Long-Term Outcomes of Vulvar or Vaginal Cancer Patients Undergoing Laparoendoscopic Single-Site Inguinal Lymphadenectomy
Authors: Xu Jingyun , Yu Tianxiang , Ding Bo , Ren Mulan , Shen Yang
Published: June 2022

Objective: To evaluate the long-term outcomes of vulvar or vaginal
cancer patients undergoing laparoendoscopic single-site inguinal
lymphadenectomy (LESS-IL). Design: Prospective cohort study. Setting:
Single centre in Zhongda Hospital, Southeast University from July 2018
to April 2021. Population: A total of 16 women diagnosed with vulvar or
vaginal cancer. Methods: Women with vulvar or vaginal cancer underwent
LESS-IL performed by the same surgeon from July 2018 to April 2021. Main
outcome measures: Short- and long-term complications, and oncologic
outcomes Results: A total of 16 patients undergoing 28 LESS-IL
procedures were identified, among whom 4 underwent unilateral LESS-IL.
Median numbers of excised groin lymph nodes were 9.0 (6.5-11.8) and 10.5
(8.3-12.0) in each left and right groin, respectively. Short-term
complications occurred in 4 (25%) patients, including 18.7% lymphocele
and 6.3% wound infection. Long-term complications regarding lower limb
lymphedema appeared in 6 (37.5%) patients. Most of the short- and
long-term complications were Clavien-Dindo 1 or 2, accounting for 90%
of all postoperative issues. After a median follow-up of 23 (17.3‐31.8)
months, only 1 patient (6.3%) had isolated inguinal recurrence at 13
months postoperatively. No local or distant recurrence occurred.
Conclusion: Our results suggest that LESS-IL is associated with little
incidence of complications and promising oncologic outcomes, further
demonstrating the safety and feasibility of LESS-IL technique in
patients requiring IL. Keywords Laparoendoscopic single-site inguinal
lymphadenectomy, vulvar cancer, vaginal cancer, compliaction, oncologic
outcome
Differentiation Syndrome and Coagulation Disorder -- Comparison between treatment with Oral and Intravenous Arsenics in Pediatric Acute Promyelocytic Leukemia.
Authors: Luo Jie-si , Zhang Xiao-Li , Huang Dan-Ping , Chen Yi-Qiao , Wan Wu-Qing , Mai Huirong , Chen Hui-Qin , Wen Hong , Liu Ri-Yang , Chen Guohua , Li Yu , Luo Xue-Qun , Tang Yan-Lai , Huang Li-Bin
Published: June 2022

Background: Realgar-Indigo naturalis formula (RIF) containing A
S as a major ingredient is an oral
arsenic available in China. The efficacy of RIF on pediatric acute
promyelocytic leukemia (APL) is comparable to arsenic trioxide (ATO).
However, it remains to be explored that the effects of these two
arsenicals on differentiation syndrome (DS) and coagulation disorder
which are the two main life-threatening events in children with APL.
Procedure: We analyzed 68 consecutive children with newly
diagnosed APL involved in SCCLG-APL study (NCT02200978). Patients
received all-trans retinoic acid (ATRA) on day 1 of induction therapy.
ATO (0.16 mg/kg·d) or RIF (135 mg/kg·d) was administrated on day 5 after
mitoxantrone on day 3 (non-high-risk group, NHR) or day 2-4 (high-risk
group, HR). Results: The incidences of DS were 3.0% and 5.7%
in ATO (n = 33) and RIF (n = 35) groups ( p = 0.590), and 10.3%
and 0% in patients with and without differentiation-related
hyperleukocytosis, respectively ( p = 0.04). The dynamic changes
of WBC between the ATO and RIF groups were not statistically different.
However, patients with high WBC counts or percentage of promyelocytes in
peripheral blood tended to develop differentiation-related
hyperleukocytosis. The improvement of coagulation indexes in the ATO and
RIF groups had no statistical difference. Fibrinogen and prothrombin
time had the quickest recovery rate. Conclusions: This study
provides evidences that the incidence of DS and recovery of coagulopathy
are similar whenever treating with RIF or ATO in children with APL.
Time is a critical factor in evaluating indirect hERG inhibition by Oligonucleotide Therapeutics
Authors: Qu Yusheng , Kirby Robert , Gao BaoXi , Vargas Hugo
Published: June 2022

Background and Purpose: In accord with ICH S7B guidelines, an in vitro
human ether-a-go-go-related gene (hERG) assay is conducted to assess
risk for delayed ventricular repolarization. Function of hERG could be
affected by direct and acute mechanisms, or by indirect and chronic
mechanisms. Oligonucleotides have unique mechanisms and time courses of
action. To help frame the strategy of hERG assay for siRNA,
investigation was performed to assess the time-course for siRNA-mediated
inhibition of hERG function and gene expression. Experimental Approach:
Commercially available siRNAs of hERG were evaluated in a stable hERG
expressed cell line by whole-cell voltage clamp using automated
electrophysiology and polymerase chain reaction (PCR). Key Results: In
the acute hERG study, no effects were observed by applying 100 nM siRNA
for 20 min. The chronic effects of 100 nM siRNAs on hERG function were
evaluated by transfection and recorded over 8-48 hrs, after
transfection. At 8 hrs there was no significant effect, while 81%
reduction was observed at 48 hrs. Measurement of hERG mRNA levels
demonstrated a 79% and 93% decrease of hERG mRNA at 8 and 48 hrs.,
respectively, consistent with a preceding effect on gene expression
compared to protein function. Conclusion and Implications: Results
presented here indicate that an anti-hERG siRNA requires a long exposure
time (48 hrs.) in the hERG assay to produce a maximal effect; short
exposures (20 min-8 hrs.) had no effect. These findings imply that
oligonucleotides require specific and appropriate protocols to
characterize their potential off-target effects on hERG channel.