bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma
Authors: Mukherjee Purna , Augur Zachary M. , Li Mingyi , Hill Collin , Greenwood Bennett , Domin Marek A. , Kondakci Gramoz , Narain Niven R. , Kiebish Michael A. , Bronson Roderick T. , Arismendi-Morillo Gabriel , Chinopoulos Christos , Seyfried Thomas N.
Published: May 2019

Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. The glutamine antagonist, 6-diazo-5-oxo-L-norleucine (DON), was administered together with a calorically restricted ketogenic diet (KD-R) to treat late-stage orthotopic growth in two syngeneic GBM mouse models: VM-M3 and CT-2A. DON targets glutaminolysis, while the KD-R reduces glucose and, simultaneously, elevates neuroprotective and non-fermentable ketone bodies. The diet/drug therapeutic strategy killed tumour cells while reversing disease symptoms, and improving overall mouse survival. The therapeutic strategy also reduces edema, hemorrhage, and inflammation. Moreover, the KD-R diet facilitated DON delivery to the brain and allowed a lower dosage to achieve therapeutic effect. The findings support the importance of glucose and glutamine in driving GBM growth and provide a therapeutic strategy for non-toxic metabolic management.
Introduction to Antibody-based Food Analysis
Authors: O'Kennedy Richard
Published: May 2019

This book provides a description of antibody-based technologies used in food analysis, which are widely applied and offer significant advantages when linked to a range of detection stratagems. In this book all the key elements associated with the use of antibody-based detection strategies are addressed ranging from the structure and production of antibodies to established and newly applied detection platforms.
The Importance of Bioanalytical Parameters and Statistical Analysis in Immunoassays for Food Analytes
Authors: Vashist Sandeep Kumar
Published: May 2019

Immunoassays play a prominent role in the food industry for the detection of single or multiple analytes in food samples, thereby contributing to the development of high-quality food products. There is a need for stringent bioanalytical testing of food samples and robust statistical analysis taking into account the growing concerns for public health and safety. Statistical analysis plays a prominent role in the food industry for the determination of various bioanalytical parameters, which should comply with the recent guidelines provided by the regulatory authorities. The guidelines should be updated regularly based on the continuously evolving technologies and recent trends in food testing. The developed immunoassay should be precise, accurate, highly sensitive, specific, and robust for intended end-user application, i.e., the detection of analytes in food products. This chapter provides an overview of the critical bioanalytical parameters and the importance of statistical analysis in immunoassays for food analytes.
Novel Recombinant Antibody and Protein-based Approaches for Analysis of Food and Food Contaminants with Particular Relevance to Asia
Authors: Yamabhai Montarop , Rangnoi Kuntalee , Sompunga Pensuda , O'Kennedy Richard
Published: May 2019

An overview of food safety issues in Asia is presented in this chapter. An update on research and innovations related to novel recombinant antibody and protein-based approaches for analysis of food and food contaminants in Asia is reported, with China as the leading country of relevance, followed by South Korea, Japan, and Thailand. The main focus is on mycotoxins, followed by pesticide detection. Different recombinant formats, especially scFv and VHH, have been used. In addition, anti-idiotypic VHH and peptide mimotopes have been used in ELISA-based formats. For foodborne pathogens, recombinant antibodies and peptides identified using phage display technology have been used as affinity reagents for rapid detection.
Antibody-based Sensors for the Detection of Pathogens of Potato and Barley
Authors: Cassedy Arabelle , Mullins Ewen , O'Kennedy Richard
Published: May 2019

Potato and barley are crops of major economic importance, being respectively the fourth and fifth most produced crops worldwide. Each year infection of these crops by pathogens, such as fungi, bacteria, nematodes, viruses and oomycetes, results in yield losses of as much as 40%. This poses a risk to both food and economic security for countries which are reliant on the food supply or income from these crops. Currently, crop pests are mainly managed by chemical spraying of pesticides, insecticides, fungicides or bactericides; however, the global push for a reduction of chemical usage in agriculture has led to a demand for new pest-control measures. The introduction of routine testing using antibody-based assays, or immunoassays, could be part of the solution to such demands. Such assays allow for the rapid and accurate diagnostic testing of a wide range of pathogens, making them extremely appealing for use in on-site crop testing. This, alongside progress in the miniaturisation of sensing platforms, could provide a means for farmers to routinely test their crops, thus allowing disease management through selective treatment and quarantine, rather than blanket treatment by chemical spraying, which is typically based on the growth stage of the crop as opposed to the presence, absence or severity of disease.
Anomalously low activation energy of nanoconfined MgCO3 precipitation
Authors: Miller Quin R. S. , Kaszuba John P. , Schaef Herbert T. , Bowden Mark E. , McGrail B. Peter , Rosso Kevin M.
Published: May 2019

Experimental study of nanoconfined MgCO3 nucleation and growth processes reveals elevated kinetics due to less strongly hydrated Mg2+.
Sulfur vacancy-rich N-doped MoS2 nanoflowers for highly boosting electrocatalytic N2 fixation to NH3 under ambient conditions
Authors: Zeng Libin , Chen Shuai , van der Zalm Joshua , Li Xinyong , Chen Aicheng
Published: May 2019

Sulfur vacancy-rich N-doped MoS2 nanoflowers act as highly effective electrochemical catalysts for efficient nitrogen reduction.
Metal-free C–H amination of arene with N-fluorobenzenesulfonimide catalysed by nitroxyl radicals at room temperature
Authors: Miao Qi , Shao Zhong , Shi Cuiying , Ma Lifang , Wang Fang , Fu Ruoqi , Gao Haochen , Li Ziyuan
Published: May 2019

The first C–H amination of arene with NFSI via organocatalysis is disclosed, which can be achieved at room temperature with a broad substrate scope.
Pillararenes as macrocyclic hosts: a rising star in metal ion separation
Authors: Chen Lixi , Cai Yimin , Feng Wen , Yuan Lihua
Published: May 2019

This feature article reviews the development of functionalized pillararenes as supramolecular materials for lanthanide and actinide separation and heavy metal removal.
Two-step epitaxial growth of NbON (100) thin films on rutile-type TiO2 (101) substrates and reduction of residual carrier concentration by RF reactive sputtering
Authors: Kikuchi Ryosuke , Nakamura Toru , Kaneko Yasushi , Hato Kazuhito
Published: May 2019

Two-step growth makes it possible to grow NbON epitaxial films and minimize anion-related defects in the NbON films.
X-ray radiation-induced amorphization of metal–organic frameworks
Authors: Widmer Remo N. , Lampronti Giulio I. , Casati Nicola , Farsang Stefan , Bennett Thomas D. , Redfern Simon A. T.
Published: May 2019

Accumulation of radiation damage from synchrotron X-rays leads to complete amorphization of the initially crystalline metal–organic frameworks ZIF-4, ZIF-62, and ZIF-zni. The mechanism of this transformation is studied as a function of time and temperature and is shown to be non-isokinetic.
Order–disorder transition in p-oligophenyls
Authors: Zhang Kai , Wang Ren-Shu , Chen Xiao-Jia
Published: May 2019

Poly(para-phenylene) has been recognized as one important family of conducting polymers upon doping with donors or acceptors.
Correction: Improving the inhibitory effect of CXCR4 peptide antagonist in tumor metastasis with an acetylated PAMAM dendrimer
Authors: Liu Changliang , Duan Hongyang , Zhao Zijian , Li Wenzhe , Ma Lilusi , Fang Xiaocui , Wang Chen , Yang Yanlian
Published: May 2019

Correction for ‘Improving the inhibitory effect of CXCR4 peptide antagonist in tumor metastasis with an acetylated PAMAM dendrimer’ by Changliang Liu et al., RSC Adv., 2018, 8, 39948–39956.
Modeling the magnetomechanical behavior of a multigrain magnetic particle in an elastic environment
Authors: Vaganov Mikhail V. , Borin Dmitry Yu. , Odenbach Stefan , Raikher Yuriy L.
Published: May 2019

A new experimentally supported model of the magneto-mechanical behavior of a multigrain magnetically hard microparticle embedded in an elastic matrix is presented.
Serum levels of Trimethylamine-N-oxide in patients with ischemic stroke
Authors: Rexidamu Maimaiti , Li Hongmei , Jin Haiyan , Huang Jiankang
Published: May 2019

Objective: Accumulating evidence suggests that Trimethylamine-N-oxide (TMAO), a gut microbial metabolite, is implicated in the pathogenesis of many cardiovascular diseases. The aim of the present study was to investigate the serum levels of TMAO in Chinese patients with ischemic stroke.

Method: In the present study, 255 consecutive patients with first-ever acute ischemic stroke and 255 age and gender-matched healthy volunteers were included for testing serum TMAO. Stroke severity was determined by the NIH Stroke Scale (NIHSS). The stroke severity was dichotomized as minor (NIHSS ≤ 5) and moderate-to-high clinical severity (NIHSS > 6).

Results: The serum levels of TMAO in stroke ranged from 0.5 to 18.3 μM, with a median value of 5.8 (interquartile range (IQR), 3.3–10.0) μM, which was higher than in those controls (3.9; IQR, 2.6–6.1 μM). The median level of TMAO in those patients was significantly lower than in those moderate-to-high stroke patients (4.1 μM [IQR, 2.8–6.2] vs. 9.1 μM [5.1–11.0]; P<0.001). In univariate and multivariable models, the unadjusted risk of moderate-to-high stroke was increased by 31% (odds ratio (OR) = 1.31 [95% confidence interval (CI): 1.21–1.42], P<0.001) and 22% (OR = 1.22; 95% CI = 1.08–1.32; P<0.001), when TMAO was increased each by 1 μM. Based on the receiver operating characteristic (ROC) curve, the optimal cut-off value of serum level of TMAO as an indicator for screening of moderate-to-high stroke was estimated to be 6.6 μM, which yielded a sensitivity of 69.3 % and a specificity of 79.0%, with the area under the curve at 0.750 (95% CI, 0.687–0.812).

Conclusions: Higher TMAO levels were associated with increased risk of first ischemic stroke and worse neurological deficit in Chinese patients.
Secrecy outage analysis over fluctuating two‐ray fading channels
Authors: Zhao Hui , Yang Liang , Pan Gaofeng , Alouini Mohamed‐Slim
Published: May 2019

In this Letter, the authors analyse the secrecy outage probability (SOP) over fluctuating two‐ray fading channels but with a different definition from the one adopted in Zeng et al. Following the new defined SOP, they derive an analytical closed‐form expression for their proposed SOP, as well as an asymptotic formula valid in the high signal‐to‐noise ratio region of the source to destination link. In the numerical results section, they perform some Monte‐Carlo simulations to validate the accuracy of their derived expressions, and also present the probability gap between their proposed SOP and the SOP in Zeng et al..
Extended ADI‐FDTD for anisotropic magnetised graphene sheets
Authors: Gao Jian‐Yun , Wang Xiang‐Hua , Teixeira Fernando L.
Published: May 2019

The unconditionally stable alternating‐direction‐implicit finite‐difference time‐domain (ADI‐FDTD) method is extended for modelling anisotropic magnetised graphene sheets. In contrast to the conventional method for isotropic media, two additional sub‐stepping calculations are applied to incorporate anisotropic medium properties. The unconditional stability of the proposed extended method is examined numerically. The method is applied to study the transmission properties of graphene sheets. Numerical results show that the proposed method is more accurate than the recently developed locally one‐dimensional FDTD method.
Compact dielectric resonator antenna with bandwidth enhancement via loading of shorting pins
Authors: Liu Neng‐Wu , Chen Xin‐Peng , Zhu Lei , Liu Zhong‐Xun , Fu Guang
Published: May 2019

A novel compact cylindrical dielectric resonator antenna (DRA) with improved bandwidth is proposed in this study. By loading the shorting pins around the nodal line of electric fields of TM011 mode of the DRA, an additional shorting‐pin mode could be excited for the antenna, while keeping an almost constant frequency of TM011 mode. After that, the DRA loaded with two, three, and four shorting pins is further studied. The results indicate that the resonant frequency of the shorting‐pin mode is progressively pushed up by increasing its number. With these arrangements, an improved‐bandwidth is obtained for the DRA loaded with four pins. Finally, the proposed DRA is fabricated and measured to validate the predicted performances. The results show that the DRA has gained an enhanced‐bandwidth (|S11| < –10 dB) of about 17% (3.65–4.33 GHz) under the radiation of dual modes, while keeping the stable conical radiation patterns. Most importantly, the height and diameter of the dielectric radiator are maintained as small as 0.09 and 0.32 free‐space wavelength, respectively.
Electric utility on the basis of renewable energy sources at realisation of “Smart city” concept
Authors: Shilkina Svetlana
Published: May 2019

Realisation of “Smart city” concept is connected with introduction of activities as to increase in energy efficiency and resource saving in the area of electric utility industry, including for the account of applying renewable energy sources (RES). Introduction of concept elements is economically justified not only in big megapolises, but in minor residential areas, as well. Notwithstanding the growth in power production with the employment of sun and wind technologies, the share of RES-based power generating plants in Russia, remains inconsiderable and amounts to approximately 0.1% of the total registered output of country’s power sources. Development of this perspective sphere is mainly carried out in those Russian regions where diesel fuel is used at very high potential capacities of the sun and wind power. Projects as to RES development in Russia are economically substantiated for isolated power-engineering systems, their introduction allows to cut consumption rate of expensive diesel fuel which is environmentally unfriendly. The estimates as referred herein, evidence a necessity to substitute elements of power-generating equipment of diesel-powered plants with solar-power farms. Development of renewable energy-generating industry in the country must be facilitated, by accelerated introduction of this resource in the regions with autonomous power-supply, where RES provides a fairly good economic effect.
Energy economic suitability of the use of “air-air” recuperators in the climatic conditions of the republic of Armenia
Authors: Petrosyan Artashes
Published: May 2019

The issues of energy saving in buildings are considered by using recuperators to save heat and cold, lost when removing air from the buildings space and transferring some of the energy to the fresh air that is supplied into the premises. Such heat exchangers can be a part of the mechanical ventilation system, as well as stand alone and carry out partial (due to heat exchange) or complete heating of fresh air (by using a heat transfer agent or an electric heater). Depending on the place of application and the recuperator type, they can have different energy efficiency or thermal efficiency, price, and respectively, energy economic indicators and payback period. Often, the developers and plants, the manufacturers go on partial deterioration of these indicators to reduce the product price, suggesting to use simpler structures, in particular, recuperators of “air-air” type with a different number of pipes in the heat exchanger. In the present material, the methods of calculation of multi-pipe recuperators for utilization of heat of exhausted air, having the simplest structures, are given. The areas of expedient use in various climatic conditions of the Republic of Armenia are determined. The criteria are the given expenses, fuel economy, their manufacture costs.
Assurance of heating systems maintenance reliability through the creation of a risk management system of the heat-supplying organizations
Authors: Verstina Natalia , Badalova Anna , Evseev Evgeny
Published: May 2019

The matters of the organization of risk management of the heat-supplying organizations (HSO), focused on the increase in the reliability of the heating systems maintenance are considered in the article. The characteristic of the current maintenance conditions of HSO in the countries of the former Soviet Union, which distinction is the existence of some state plans for the change of the heat-supplying industry development financing in the Russian Federation and Uzbekistan, similar in the target orientation. The new methodological-and-methodical approach to the determination of the interrelation between the heating systems maintenance reliability and the risks of HSO with their differentiation according to the significance values, complemented with the classification of risks on the basis of the equilibrium-and-balanced approach and the formation of the matrix for risk analysis is offered as the research result. Due to the purpose of the creation of risk management system in HSO the current state of the information support of their activity, which is recognized insufficient, is studied. The results of the analysis of the interrelation between the reasons of failures during the delivery of heat to consumers because of risks, having constructive, technologic and labour character, and stages of the heating systems lifecycle are presented. Three models of the assessment of the level of engineering structures reliability, depending on the assessment of situation in HSO are offered to the discussion. The risk management system in HSO is considered as an important condition of the reliability assurance, the substantial characteristic of its main components is given.
Devices for cleaning tap water
Authors: Govorova Zhanna , Podlesnov Nikita , Govorov Vadim
Published: May 2019

The condition of the water distribution network of the centralized water supply and its high wear, at the same time with other factors, affect the quality of drinking water transported to the consumer of drinking water. The most common causes of the secondary pollution of drinking water during its transportation are considered, as a result of which the concentration of dissolved and undissolved impurities and corrosion products increases, unpleasant smells and tastes appear in the water, microbiological and parasitological indicators deteriorate. Along with measures to improve the technology of water purification at waterworks, replacement, cleaning and repair of pipelines, in practice domestic water purification devices are used. The results of studies of the effectiveness of additional purification of drinking water are presented in the article. The water is taken for analysis from different points of the Moscow distribution network on water treatment devices: “JNT-RO”, filter “Aquafor”, installation “OSMO 300” with a capacity from 187.2 to 380 l/day. The results showed that the original tap water in its qualitative composition met the regulatory requirements for drinking water, and after passing through the elements of water purification devices during the stated service life the quality characteristics of turbidity - 100%, chromaticity - 84.6-100%, Total Dissolved Solids (TDS) - 84.4-94.2% and hardness - 87.3-93.8% improved. The calcium content in purified water ranged from 6.8 to 12 mg/l.
Methodical approach to the justification of project design decisions on the application of “green” building technologies
Authors: Beliakov Sergei , Kapustkina Anna
Published: May 2019

The article is devoted to one of the most relevant areas of research in modern Russian conditions - the consideration of issues related to the formulation and justification of methodological approaches to the design of buildings belonging to the category of “green” construction in smart city concept. Designing such facilities includes a comprehensive analysis of the building as a single energy system, and also includes the study of issues related to energy conservation at all stages of the life cycle of the property, the environmental regime of land use, water conservation and wastewater treatment use in the construction of environmentally friendly materials, etc. Planning of any investment and construction project is associated with an analysis of the feasibility of its implementation, taking into account all stages of its life cycle: conceptual study and design, construction, operation, utilization. When planning projects using “green” building technologies, the solution of these problems requires the use of specific approaches and tools. Substantiation of decisions on resource and energy saving in the design of buildings can be carried out on the basis of the following methodological approaches: construction and (or) functional. Based on the presented approaches, the authors have developed a comprehensive algorithm for planning and implementing an investment and construction project using “green” building technologies.
Study of resistance to climatic factors of epoxy coatings modified by plant oils and their functionalized derivatives
Authors: Gotlib Elena , Nguyen Anh , Yanov Vladislav , Sokolova Alla
Published: May 2019

Epoxy coatings while in-service are regularly exposed to various atmospheric factors including elevated temperature, moisture, solar irradiation, precipitation, fog and others. Those factors accelerate the processes of oxidative and photochemical degradation of epoxy materials which could significantly affect their service life. In the present paper the study of resistance of epoxy materials to climatic factors was carried out in the Artificial weather apparatus simulating external environmental activities by cycles of accelerated tests. It was proven that various types of modifiers exercise influence upon the mass growth of epoxy materials and consequently their sorptive processes. The analysis of investigated results has shown that in epoxy polymer exposed to moisture one could observe competing processes of the growth of cross-linking degree and its plasticization. It was stated that no exact correlation is observed between the degree of cross-linking of epoxy materials and their water fastness and resistance to climatic factors. The authors have proven that outside resistance of epoxy coatings is higher for epoxy compositions modified by soy oil and its functionalized derivatives. Epoxy compositions modified by rubber seed oil exhibited the maximum structural change caused by the impact of climatic factors.
Mathematical Model of Coextrusion Molding of Polymer-concrete Building Structures
Authors: Dyadichev Valery , Kolesnikov Andrey , Dyadichev Aleksandr , Dyadicheva Ekaterina , Menyuk Sergey , Chornobay Svitlana
Published: May 2019

The research identifies the optimality criterion of the technological process of the coextrusion molding of polymer-concrete building structures in the form of volumetric capacity as the correlation between forms quantity and technological cycle time. The set of parameters value constraints is made. The set consists of kinematic constraints, extruder’s maximum power constrain, maximum motor torque constraint for the extruder trouble-free operation, constraint on the stress rate of the shift between layers, constraint on product cooling time, and minimum melt viscosity constraint. As a result, the task of coextrusion molding process improvement reduces to the task of linear programming. With the help of mathematical modelling the dynamics of cooling process of the preform in the mould is studied. The paper scrutinizes the influence of bulging pressure on the plybond strength in the multilayer polymer system in the manufacturing process of different capacity items.
Assess the Effectiveness of protective Concrete coatings of microbiological sulfuric acid Aggression
Authors: Sopov Viktor , Danchenko Julia , Latorez Ekaterina
Published: May 2019

Specification of corrosion processes in sewerage networks, the predominant role of microbiological processes in them requires the protection of concrete with materials resistant to specific biogenic sulfuric acid aggression. The effective protective materials, in this case, are those that, in addition to acid-proofing materials, have bactericidal properties. Polymer composite materials (PCM) of cold curing based on modified epoxy-resin, resins with dispersed oxides as fillers are widely used in construction. Unique properties and simple technologies make it possible to use them as injection formulations for repair, restoration and restoration of building structures and structures, waterproofing and facing materials, for impregnating, gluing and coating metal, wooden, brick and concrete building structures and parts. In the reconstruction and restoration of sewerage collectors operating under conditions of exposure to liquid biochemically aggressive media with mineral acids and organic substances, particular attention is paid to the permeability of repair materials. Based on the results of the study, PCM compositions were chosen whose estimated lifetime is about 20 years, ensuring reliable protection of the sewage collectors from corrosion.
Development of PVC films, resistant mold influence
Authors: Mazitova Aliya , Maskova Albina , Aminova Guliya
Published: May 2019

Along with the use of plasticizers in the development of polymeric materials with specific properties, special substances such as fungicides are also used because of the negative impact on the polyvinyl chloride materials of microorganisms.

In the present work, the possibility of practical application of butylbutoxyethyl phthalate (BBOEP) and dibutoxyethyl adipate (DBOEA) as plasticizers, and 4-amino-1,4,5,6-tetrahydro-1,2,4-triazinone-5 as a fungicide, in PVC films. The first additive was obtained by the esterification of phthalic anhydride (adipic acid) with hydroxyethyllylated butanol. The second additive was obtained on a base of ethyl monochloroacetate.

According to the conducted experiments, it was it was found that when exposed to mold fungi, some physic-mechanical characteristics of plastic compounds deteriorate.

During the study of the resistance to fungi of plastic compounds, it was found that compositions made on the basis of PVC with BBOEP have got high funginertness, while compositions prepared with using of DBOEA turned out to be unstable against to microorganisms. For the prevention infection by the fungus of the obtained plastic compounds based on adipic acid, a proposed fungicide was used. Primary studies have shown that DBOEA with the addition of the fungicide for resistance to fungi is not inferior to BBOEF.
Stress relaxation of wood-polymer composites of savewood
Authors: Askadskii Andrey , Matseevich Tatyana , Gorbacheva O.A.
Published: May 2019

Experiments on stress relaxation on the samples representing fragments of terraced boards have been carried out. Matrix polymer is polyvinyl chloride (PVC). The combined wood filler, which is a mixture of wood flour and chalk, has been used. Measurements conducted at different permanent deformations of compression from 2 to 5% and temperatures from 20 to 70°C. Found that under all conditions the relative relaxation takes small values, indicating the long-term conservation of the mechanical workability of the products. Nonlinear mechanical behavior is evident already at 3% strain. At temperatures from 20 to 35°C relaxation processes take place almost identically, without reduction in initial and final stress. At temperatures of 50 and 70°C both stresses are reduced. The master curve is plotted, which allows prediction the mechanical behavior for a long time.
Use of passive safety supporting structures
Authors: Michałek Jarosław
Published: May 2019

Road safety issues have been raised for many years in subsequent national and EU documents. An example of a Polish document is the National Road Safety Program for 2013-2020 [1]. The priorities and measures adopted in the document [1] relate mainly to the environment and road furnishings making up the so-called passive road safety. In accordance with PN-EN 12767: 2008 [2], road lighting columns, as well as supporting structures for vertical road marking and traffic safety devices should be constructed in such a way that they do not pose a threat to road users in case of unforeseen situations ending up in a collision. Three categories of passive safety of support structures depending on the level of energy absorption during vehicle impact can be distinguished: high energy absorbing (HE), low energy absorbing (LE) and non-energy absorbing (NE) energy. The article presents an overview of solutions of several countries (USA, Norway, Sweden, Finland, Great Britain, Slovakia and Poland) in the use of support structures that minimize the impact of a collision. Particular attention was paid to the fact that due to the potential risk of secondary injuries sustained by other road users (pedestrians and cyclists) in relation to a specific installation site and designated speed limit, constructions in the HE or NE absorption class or even Class 0 constructions should be used.
Evaluation of dynamic Parameters and developing calculation Methods of Parameters of pneumatic vibratory Mechanism of Bag Filters regeneration
Authors: Sopov Viktor , Emelianenko Nikolay , Balera Nikolay , Zhuravlov Yuri
Published: May 2019

A scheme of membrane pneumatic mechanism of shaking bag filter for cleaning the air from dust is developed. The research findings of dynamics of air mechanic vibratory bag filter system are shown. The concept of revised methods for calculating main parameters of membrane pneumatic vibratory mechanism of the bag filter regeneration is developed.
Mathematical Game Theory in Civil Engineering Fire Safety
Authors: Shikuskaya Olga , Abuova Galina , Vatunskiy Ivan , Shikulskiy Mikhail
Published: May 2019

In the analysis of the project documentation of a two-storeyed sports complex it was established that despite compliance of the project to all standards in the fire safety field, under certain conditions there is a danger of a delay of full people evacuation from the gym room in case of fire that can entail people’s death. For the purpose of ensuring fire safety several versions of space-planning decisions were considered. The scientific literature analysis showed efficiency of game theory use in the field of fire safety, however in the field of fire safety in construction it was not applied yet. Game theory Application (games with the nature in the conditions of uncertainty) for the revealed problem solution was proved. Three possible scenarios of emergence and development of the fire and four alternative space-planning decisions were considered. For all development scenarios of the fire time of critical values achievement of dangerous fire factors was defined. All necessary evacuation schemes are made and calculations are executed. On the calculated parameters basis the payoff matrix was constructed. An optimal variant of space-planning decisions was chosen. Research results showed expediency and efficiency of game theory application in the field of fire safety in construction.
Nonlinear deformation analysis for precast pre-stressed concrete beam systems
Authors: Tran Thi Thuy Van , Shapiro David
Published: May 2019

The structural systems such as road bridge beam systems (span superstructure) or beam systems used in high-rise buildings with precast pre-stressed reinforced concrete might be subjected to the load higher than the calculated load of the design process. In the process of operation the internal forces of the beams reach to a certain value, the section stiffness in elements will be changed. The change in section stiffness will lead to redistribution of internal forces in the whole system. However, that has not been included in the design process. The paper presents nonlinear deformation analysis of precast pre-stressed beam system used in road bridge span superstructure or high-rise buildings using nonlinear model of materials according to Russian construction codes to build the relationship between internal forces and section stiffness. From the calculation results, some comments will be recommended about increased load capacity in comparison with the results obtained from analysis using linear model of material.
Aspects of scheduling processes and results of the reorganization of projects in high-rise construction objects
Authors: Kazaryan Ruben , Pogodin Denis , Shatrova Anastasia
Published: May 2019

Systematization of scientific research and their elements imply that the purpose of scientific research is comprehensive study of an object, process or the phenomenon, their structure, communications and relations on the basis of newly discovered or known to science principles and methods of knowledge and also obtaining and implementation in practice of a construction reorganization new methods of the organization of a labor activity and its elements corresponding to these results. The feasibility and necessity of modeling technogenic impacts as an important element of managing the construction reorganization of objects in order to ensure the competitiveness of the proposed organizational and technological solutions are caused by a variety of reasons. The concepts and definitions related to the field of modeling of technogenic impacts are not well-established. Therefore, there are different options of the definition of the same concept. The models of technogenic impacts are considered as diagnostic if the study and use of them allow obtaining information on the causes of the identified problems. Using such diagnostic models, time series of predicted retrospective values of parameters of technogenic impacts are built. Visual displays of such time series (infographic models) are known as “trends”.
Comparative analysis of calculations of strip foundation, taking into account the influence of adjoined building with different soil models
Authors: Lobacheva Nataliia , Griniov Vadim
Published: May 2019

The necessity to take into account the properties of soil foundations, which depend not only on the conditions of their natural occurrence, but also on the stress state, led researchers to create a large number of different soil models. This article provides is to clarify the patterns and features of the three-dimensional interaction of strip foundations with the soil base in conditions of dense urban development with the use of various design soil models and comparison with field observations. Three soil models (the Mohr-Coulomb model, the Hardening-Soil model, model of the Klepikov stiffness coefficient) are considered. The calculation stages displayed a true picture of the construction of a new building (dismantling of the floor of an existing building, excavation, etc.). As a result of numerical experiments with a use of Plaxis and methods for calculating structures on a deformable base was received values settlement of strip foundations in applying three soil models. The difference of the calculated values of strip foundation settlement is defined in percentage. The geodesic monitoring confirms the validity of the research.
The modeling of the «diaphragm wall» with the anchor without the use of distribution beams
Authors: Znamenskiy Vladimir , Morozov Evgeniy , Pekin Dmitrii , Chunyuk Dmitry
Published: May 2019

The article describes the features of modeling monolithic trench “diaphragm wall” with ground anchors without the use of distribution beams on the progressive collapse caused by the failure of one of the anchors. In the simulation of the above calculation case, in the flat formulation commonly used in practice, it is assumed that the “diaphragm wall” is a continuous structure in the longitudinal direction, without taking into account the presence of vertical joints formed between the grippers when concreting the fence and the lack of connection between the longitudinal reinforcement of adjacent reinforcement spatial frameworks. The performed calculations show that the failure to take into account these circumstances leads to a significant reassessment of the ability of the “diaphragm wall” to redistribute the load from the broken anchor to the neighboring anchor and can lead to an incorrect assessment of the results of the calculation for a progressive collapse. The need to take into account the reduction of structural rigidity of the “diaphragm wall” due to the formation of cracks in two directions is also shown.
Assessing the pile base capacity from a Static Load Test on model piles
Authors: Baca Michał , Brząkała Włodzimierz , Rybak Jarosław
Published: May 2019

A static load test of a pile provides information about the pile bearing capacity. Nevertheless sometimes more precise information can be needed, e.g. what part of load applied to the pile is carried by its base and its shaft. Many kinds of bi-directional static tests offer the possibility of a separate investigation of the behaviour of pile base and shaft. In these tests, however, the shaft works in a different direction than in actual pile working conditions. In this paper, the authors focus on the results of a static load test on model piles, which make it possible to solely investigate the pile base capacity. The paper describes the construction of a test stand and the testing procedure, and presents the first results of the preformed tests.
Slope stability analysis in the case of probabilistic and semi-probabilistic design method
Authors: Szabowicz Hubert
Published: May 2019

This paper addresses the issue of probabilistic and semi-probabilistic modelling of soil slopes. A slope made of cohesive-frictional soil of specific geometry was analysed as an example. Results were calculated for two methods using the Z-Soil finite element software. It has been assumed that the probability distributions of strength parameters, cohesion and internal friction angle are normal distributions with average values and coefficient of variation = 0.2. Random finite element method (RFEM) has been used for probabilistic modelling. Random fields of cohesion and internal friction angle have been generated using the Fourier series method (FSM). Monte Carlo simulation has been used to calculate the statistics of the slope factor of safety in order to determine the probability of failure. Moreover, assumed parameter distributions allowed to determine safe characteristic values used in the semi-probabilistic partial factors method. Both approaches have been compared in the article.
Numerical approach for estimation of stress strain state of deep tunnels
Authors: Farkhadjan Adilov , Bakhtiyor Yuldoshev , Rustam Abirov , Mirzakhid Miralimov
Published: May 2019

Numerical approach and results of theoretical calculation of deep tunnels are described in this issue. Here described surrounding continuum is fractured rocks. Calculation provided in static case. Results of this investigation aimed for estimation of stress state and development of strengthening measures of deep excavations.
Assessment of dynamic behaviour of earth dams taking into account large strains
Authors: Mirsaidov Mirziyod , Sultanov Tokhirjon , Yarashov Javlon , Toshmatov Elyor
Published: May 2019

This paper presents the results of the assessment and prediction of the dynamic behavior of earth dams of various heights, taking into account large strains (geometric nonlinearity) and inhomogeneous features of structures under multi-component kinematic effects. A mathematical model, methodology and algorithm for estimating dynamic behavior of earth dams taking into account inhomogeneous features of structures and large strains in spatial and plane statements are given. Dynamic behavior of the models of the Pachkamar, Gissarak and Nurek earth dams has been studied taking into account large strains and inhomogeneous features of structures in various pre-resonant and resonant modes under multi-component kinematic effect. A number of new effects associated with the manifestation of large strains in the structure under various dynamic influences are revealed.
Influence factors on the temperature field in a mass concrete
Authors: Aniskin Nikolay , Nguyen Trong-Chuc
Published: May 2019

In construction practice of concrete mass needs a large amount of concrete. Due to the small surface area to volume ratio, the concrete mass is often happening thermal cracking caused by the release of heat during the hydration of the cement. The causes of thermal cracking in concrete mass are complex but the main reason is the increase in temperature in the concrete structure. Provide measures to control the maximum temperature concrete mass is very absolutely necessary. A finite element model of the concrete mass was established by the software Midas civil, the temperature field in the concrete mass has been determined and a mathematical model was created that adequately describes the influence factors on the temperature field in a concrete mass such as unit cement content, cement maximum heat released, the placing temperature of concrete and the water temperature in order to determine the optimal parameters.
The evaporation loss from water reservoirs of Uzbekistan
Authors: Gapparov Furkat , Kodirov Sobir , Mansurov Safar
Published: May 2019

The article deals with the results of the calculation of annual evaporation losses from the open water surfaces of reservoirs of Uzbekistan. For the estimations, we used the formula of the dependence of the temperature of open water surfaces of the reservoirs with the air temperature and average depth of them, and the tendency of air temperature change over time. The relationship between the wind speed above reservoirs and the weather station was defined.
Oxygen Regime Control in Water Body Amelioration
Authors: Borovkov Valery , Karaichev Ivan
Published: May 2019

An important aspect of water body amelioration is the control of the oxygen regime in water mass. Pollution of water bodies deteriorates their oxygen regime, and the natural inflow of oxygen through the free surface is not enough to compensate for oxygen consumption for pollutant oxidation. Water pollution by various substances causes damage resulting from a decrease in the ecological safety of urban water bodies. Data of World Health Organization (WHO) show that the contact of the population with polluted water bodies causes spreading of deceases, such as cholera, diarrhea, dysentery, hepatitis A, typhoid, and poliomyelitis, and creates considerable health risks.

In this context, the artificial aeration of water mass with the use of aeration systems, which improve water quality, is gaining in importance. Most widespread among such aeration systems are diffused-air aerators, in which air supplied by a compressor passes through perforated diffuser plates. The size of the perforation is often chosen with no appropriate hydraulic substantiation. The size of the resulting air bubbles, no doubt, depends on the size of perforation holes; however, the available design relationships give contradictory results depending on the immersion depth of the diffuser plate and the working pressure, which determines air discharge velocity from diffuser plate perforations. This shows that the studies along this line are of scientific and practical importance.

This article presents the analysis of the existing relationships for determining the size of air bubbles that form when air is pumped into water through nozzles of different diameters at different pumping rates; the analysis has shown the results of such calculations to differ considerably. Buckingham π-theorem was used to construct dimensionless groups, determining the relationship between the size of bubbles and the factors that govern the outflow of air into water. Dimensionless groups were used to obtain a formula for calculating the size of air bubbles at the aeration of water mass.
Hydraulic size of non-spherical solid particles
Authors: Volgina Liudmila , Romanova Anastasiia
Published: May 2019

The paper studies impact of determining the diameter of solid particles on the calculation of the hydraulic particle size in the water flow. The relevance of the topic is also connected with the use of calculation of hydraulic size in hydraulic engineering in forecasting: downstream erosion, the formation of shoals, canals, bottom spillages, etc. Most of the empirical formulas for calculating the hydraulic particle size are applicable to spherical particles. However, the nature of the solid particles rarely has a spherical shape. The aim of this work is to investigate experimentally the dependence of the hydraulic size of the diameter of the solid particles. Different approaches to determining the diameter solid particles are analyzed, as for non-spherical particles finding the diameter is an independent and complex problem. For the experimental research solid particles of different shapes and sizes were used. The diameter is included in the empirical formulas for hydraulic size linearly, and to the power of 2 or 0.5. Therefore, the dependence of the experimental hydraulic size on the diameter was correlated with the corresponding functions. The shape of the particle significantly affects the value of the hydraulic size and depends on the diameter to the power of (0.5).
Modelling of turbidity distribution along channels
Authors: Krutov Anatoly , Azimov Azam , Ruziev Sodiq , Dumanov Akmal
Published: May 2019

The purpose of the article is to develop the required and sufficient conditions under which numerical methods can be used for engineering calculations and for scientific research of hydrodynamic processes in solving practical problems related to surveying of pollutants diffusion in water flows. The conducted studies consisted in the finding out conditions under which mathematical modelling using hydrodynamic equations allows to solve engineering problems of channel hydrodynamics and, in particular, to numerically simulate the transport of suspended particles in channels. A number of additional nature of numerical models were studied in addition to approximation and stability, such as averaging over probability and over time averaging. It was noted that only stationary processes could be described by equations if they are obtained from the Reynolds equations, i.e. when using the Reynolds equations, an important class of problems with a pulsating flow under constant boundary conditions is excluded from consideration. And, if the equations are obtained directly from the conservation laws, then all the desired variables have the meaning of actual quantities averaged over the scale. That is even in the case of statistically stationary flows, using such equations, it is possible to solve nonstationary problems on large time scales.
Design features of bimetallic bridges
Authors: Makarov Aleksander , Kalinovsky Sergey
Published: May 2019

The Design and construction of metal bridges is the most reasonable from the structural and technological point of view, as well as from the standpoint of the implementation of non-standard engineering and spatial solutions. The weak point most often in this case is the efficiency of construction. To improve economic efficiency, it is recommended to use metal structures, the most loaded elements of the beams in which should be made of high-strength steels, and all other conventional rolled steel. Spans of a continuous plate should be designed in such a way that the spans moments are equal. The authors propose to assign the values of spans in accordance with their effective ratio and design the span structure of the three types of standard blocks.