bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Insights of Plant Phytochemicals Against Diabetic Neuropathy
Authors: Balkrishna Acharya , Pathak Rakshit , Bhatt Shalini , Arya Vedpriya
Published: August 2022

Diabetes and its associated complications including diabetic neuropathy have become a
menacing headache for health workers and scientists all over the world. The number of diabetic
individuals has been growing exponentially every day while the entire medical fraternity feels crippled
and unable to handle such an enormous and anarchical scenario. The disease also demonstrates
itself in the patients in numerous ways ranging from a little discomfort to death. Diabetic
neuropathy has a poor prognosis since it might go unnoticed for years after the onset of diabetes.
The etiology of the disease has been linked to oxidative stress caused by increased free radical production.
Hyperglycemia causes multiple metabolic pathways to be activated, as well as significant
oxidative stress, which becomes the major cause of cell death, culminating in Diabetic Neuropathy.
So, it is the need of the hour to find out permanent treatment for this life-threatening disease. The
primary goal of this study is to emphasize the potential importance of numerous processes and
pathways in the development of diabetic neuropathy as well as the possible role of plant metabolites
to control the disease at a molecular level. A possible mechanism was also summarized in the
study about scavenging the reactive oxygen species by a flavonoid component. The study also covered
the in vivo data of various plants and some of the flavonoid compounds actively studied
against Diabetic Neuropathy by inhibiting or reducing the contributing factors such as proinflammatory
cytokines, ROS, RNS inhibition, and upregulating the various cellular antioxidants
such as GSH, SOD, and CAT.
Effect of Suspended Solids and Organic Matter in Water on the Removal
of ZnO-NPs by Coagulation
Authors: Tao Jiaqing , Zhao Changrong , Zhuang Chang , You Zhaoyang , Shah Kinjal J.
Published: August 2022

Background:

Zinc oxide nanoparticles (ZnO-NPs) have been shown to have a non-negligible impact on the environment

Objective:

Kaolin and humic acid were used in the aqueous environment to study their effects on the removal of ZnO-NPs.

Method:

In this work, polyaluminum ferric chloride (PAFC)/cationic polyacrylamide (CPAM) coagulants were used together with kaolin and humic acid were used to study their effects on the removal of ZnO-NPs and to analyze their mechanism of action.

Results:

The results showed that the removal rate of ZnO-NPs in the humic acid system decreased by about 30% compared to that in the pure water system, and increasing the ionic strength and humic acid concentration was not conducive to removing ZnO-NPs. On the other hand, the ZnO-NPs removal rate in the kaolin system was up to 96.28%, and increasing the ionic strength and kaolin concentration contributed to the removal of ZnO-NPs. In the humic acid and kaolin systems, the effects of coagulant dosage and pH on the removal of ZnO-NPs were about the same as in the pure water system. Moreover, 5 mg/L humic acid inhibited floc growth during removal of ZnO-NPs by coagulation with PAFC/CPAM. In contrast, 5 mg/L kaolin promoted flocs growth, resulting in stronger and more stable flocs and a 5.25% increase in the fractal dimension compared to the pure water system.

Conclusion:

These results suggested that suspended solids and natural organic matter in the water could directly affect the effectiveness of coagulation to remove ZnO-NPs.
Hybrid Nanocarriers for Neurological Disorders: Diagnostic &
Therapeutic Approach
Authors: Mishra Anuradha , Ahsan Rabiya , Islam Anas , Tiwari Rohit Kumar , Dash Pragyandip P.
Published: August 2022

Background:

Around 1.5 billion people in the world are affected by complex neurological
disorders, and the figure is increasing alarmingly due to unsatisfactory clinical outcomes. To date, no
conventional formulation can show a promising effect on the control or prevention of neurodegeneration.
However, Nano delivery tools have shown better penetration and profound action on the targeted
area of the brain.

Methods:

Although existing Nano therapeutic approaches are abundant but would not reach the clinic
due to their improper bioavailability, BBB restricts its entry and causes improper biodistribution, so it
is a challenge to use certain bioactive as a potential therapy in neurodegenerative disorders. Hybrid
nanocarriers are nano-vesicular transported systems which could be utilized as carriers for the delivery
of both hydrophilic and hydrophobic compounds. Available patents on nanodelivery for therapeutic
approaches will also include in this review.

Results:

Hybrid Nano delivery system may provide good stability to polar and nonpolar compounds
and improve their stability.

Conclusion:

This manuscript updates the available findings on the Nano vesicular system to deliver
drugs for neurodegenerative disorders.
Biosynthesis of Silver Nanoparticles at Various pH Values and their
Applications in Capturing Irradiation Solar Energy
Authors: Faris Vinos Mushir , Barzinjy Azeez Abdullah , Hamad Samir Mustafa
Published: August 2022

Background:

Metallic nanoparticles (NPs), in general, are able, due to the high surface area per unit volume, to absorb the maximum incoming light flux through the vicinity of plasmonic structures and then provide local heating. Thus, silver (Ag) NPs has been used to generate heat and increase the temperature of water from solar radiation energy. The optimal plasmonic heating generation can be obtained as soon as the wavelength of the light source is close to the plasmonic resonance wavelength of Ag NPs.

Objective:

Ag NPs have been fabricated through a straightforward, cheap, as well as environmentally friendly approach. In this study, Salix babylonica L., weeping willow leaf extract has been utilized as a reducing, capping, and stabilizing agent, without using any other toxic materials. The importance of this study lies in the generation of hot electrons, which can be obtained by collecting the solar spectrum near the infrared and infrared regions, which cannot be obtained by the conventional photocatalytic devices.

Methods:

Numerous characterization techniques such as; UV-Vis, FT-IR spectroscopy, X-ray diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis were used to study the optical, chemical, structural, morphological, properties of the Ag NPs.

Results:

The impact of pH on the properties of Ag NPs and their performance to generate heat during solar irradiation have been investigated intensively. This study showed that the synthesized Ag NPs with pH value 12 is the optimum condition and can increase the temperature of water dramatically.

Conclusion:

An evaluation of the current patents displays that the field of green synthesis Ag NPs utilizing plant extracts is a vital field and produces rather stable, safe and effective Ag NPs. The novelty of this patent is that Ag NPs can be synthesized from a one-pot reaction without using any exterior stabilizing and reducing agent, which is not conceivable by means of the existing processes. This study, also, is rare and distinctive, and it demonstrates that even a slight quantity of the Ag NPs is significantly raising the temperature of water effectively.
Lesbian Gay Bisexual Transgender Questioning/Queer Two-
Spirit Adolescents and Suicidality
Authors: Tobin Valerie , Sheth Neeral K. , Thompson Hale M. , Karnik Niranjan S.
Published: August 2022

Background:

At a time when suicides are increasing throughout the United States, lesbian, gay, bisexual, transgender, and two spirit (LGBTQ2S) adolescents are at especially high risk for suicidal ideation, attempts, and completed suicide.

Objectives:

To 1) provide an overview and clinical perspective on LGBTQ2S suicidal ideation, attempts, and completed suicide; 2) discuss how the literature maps on to theories of suicide, and also points the way to clinical recommendations; and 3) give recommendations for clinical care based on this evidence.

Method:

This article uses a narrative review style to discuss the current concerns around LGBTQ2S adolescent suicide. The Social Ecological Model, the Interpersonal Psychological Theory of Suicide, and Minority Stress Theory are used describe the manner in which risks are acquired.

Results:

Emerging research demonstrates risks and protective factors in the lives of LGBTQ2S adolescents. The social context of LGBTQ2S adolescents puts them at risk for internalizing the experiences of discrimination evident in our society, In addition, there are other risk factors frequently associated with their LGBTQ2S status, such as substance misuse, homelessness, and lack of social support . Adolescents of color are especially vulnerable as they experience multiple marginalizations, often living in under resourced communities with poor access to health care. Support to families can be provided in the form of psychoeducation based on research findings. Social support is crucial and can be effectively provided in schools. Access to mental health care needs to be increased and barriers reduced.

Conclusion:

There is a need for more research, especially prospective study designs and research that centers adolescents of color and homeless adolescents. While there may be barriers to addressing the current rate of suicidality in this population, clinicians who work with adolescents can use a range of therapies to support their LGBTQ2S adolescent patients and their families, decreasing risk of suicidality.
Substitutional Tungsten Doping in Silicon Carbide Introducing Magnetic
Properties: A Computational DFT Approach
Authors: Panda Subhraraj , Patnaik Padmaja , Das Dipan kumar , Mukhopadhyay Gautam
Published: August 2022

Background:

Small concentration of magnetic material, in general, the transition metal atoms
(TM), when doped into a semiconductor, behaves as a diluted magnetic semiconductor (DMS). It has an
application to Quantum computing & spintronic devices. DMS silicon carbide has strong coupling and
high Curie temperature. The magnetic and electronic properties of SiC with TMs impurities have been in
focus for theoretical and experimental researchers.

Objective:

The objective of this work is to study the electrical and magnetic properties of tungsten doped
cubic SiC. Comparing the density of states plot with and without impurity, the change in property happening
due to the presence of tungsten is observed. Partial density of states is also plotted and interpreted.
Self-consistent spin polarized calculations are done to study the magnetic properties. Magnetic Moment is
also calculated for substitutional doping of SiC at different sites.

Methods:

Tungsten doped 3C-SiC is investigated by using the first-principle energy code, Quantum Espresso,
which uses pseudopotential within Density Functional Theory (DFT). The calculations are done
by density functional pseudopotential energy calculations in periodic systems by solving iteratively the
Kohn Sham equation in a plane wave basis set. Both norm conserving and Vanderbilt USPP are used.
Self-consistent iterations were performed until convergence of total energy and total charge was obtained.
We used different k-point meshes for different supercells with 16, 54 and 128 atoms giving results for
carious impurity percentages.

Results:

The formation energy values obtained indicate that the W impurity prefers the Si site to the C
site in cubic SiC. The presence of a narrow band towards the conduction band minimum is due to the W-d
states for Si site substitution. Both spin-up and spin-down states contribute towards the valence band, and
a small contribution goes towards the conduction band. The magnetic moment values for C site substitution
are lower than Si site substitution.

Conclusion:

It is observed W doped with Si site of cubic silicon carbide shows ferromagnetic behavior.
Hence, there is a possibility of 3C SiC doped with W at the C site to behave as a semi-insulating material.
Laccases as Gold Standard Enzymes for Biotechnology
Authors: Laha Anubhab , Prasad Anchita , Baj Kalash , Shukla Nidhi , Solanki Pooran Singh , Bandopadhyay Rajib , Nallapeta Sivaramaiah , Medicherla Krishna Mohan , Suravajhala Prashanth , Nigam Vinod Kumar
Published: August 2022

Background:

Laccases are among the oldest known multi-copper enzymes from a di-verse array of species, including bacteria and fungi, and are of great importance in different indus-tries like beverage, biosensors, textile, paper, and pulp. From the aspect of origin, interestingly, bac-terial laccase is of two kinds, namely, 3-domain conventional laccase and 2-domain small laccase. This enzyme is capable of degrading synthetic textile azo dyes, xenobiotic polycyclic aromatic hy-drocarbons, biogenic amines etc. Over the last few years, research on laccase has steadily increased based on biosensors and the understanding of known unknowns.

Objective:

In this extensive review, we focus on classification, structural differences based on assorted origins, and applications that will help to know the unknown factors about this strenuous enzyme.

Conclusion:

To better understand the origin-function relationship, hypothetical proteins of selected bacterial laccase are reviewed.
Structure Design and Performance Test of Wheat Combine Harvester
Based on Numerical Modeling
Authors: Tang Zhong , Gu Xinyang , Zhang Ben , Wang Meilin , Liang Yaquan
Published: August 2022

Background:

In response to the current needs for the development of large-scale wheat combine harvesters, this paper carried out the structure design and performance test of a large feed volume wheeled wheat combine harvester.

Methods:

Based on the characteristics of wheat plants, this paper designed a wheeled wheat combine harvester with a feed rate of 10kg/s. Subsequently, the structural parameters and design process of the main working components such as the header feeding device, the conveying device, the threshing device, the separation and cleaning device, the walking device, the cab, and the straw crushing device are elaborated. The strength of the key parts was checked by finite element simulation, and the structural parameters were optimized.

Results:

The results show that the large feed volume combine harvester which designed in this paper can achieve entrainment loss rate of less than 2.39% and cleaning loss rate of less than 0.26%, significantly lower than the current 3% loss rate and there is almost no unclean and broken situation.

Conclusion:

This research provides reference for the design of large feed volume combine harvester.
EMPOWERMENT OF THE JOGO TONGGO GROUP IN IMPROVING TRACKING CAPABILITIES AND INDEPENDENT ISOLATION IN MANGGIHAN VILLAGE, GETASAN DISTRICT, SEMARANG REGENCY
Authors:   Faculty of Nursing, Universitas Islam Sultan Agung, Semarang, Setyowati Wahyu Endang , Nurhidayanti Nunik , Handayani Agustin ,   Faculty of Nursing, Universitas Islam Sultan Agung, Semarang
Published: August 2022

Manggihan village, Getasan sub-district, Semarang district, Central Java province, which is one of the areas in Central Java, especially in Semarang district, is an area that is in the red zone related to the spread of Covid-19 in Indonesia. The existence of the Jogo Tonggo group, which is the mainstay project of the Central Java provincial government, needs to get support from all components of society. This fact encourages the importance of empowering the community to be able to independently help themselves in relation to prevention and handling of the increasingly endemic cases of Covid-19 transmission. Capacity building is an important thing that drives the success of the Movement to break the chain of transmission of Covid-19 through tracking or self-isolation management. The purpose of this activity is to improve the ability of tracking and independent isolation in Manggihan Village, Getasan District, Semarang Regency through the empowerment of the Jogo Tonggo group. The method of implementing activities is a group-based method that is carried out comprehensively which is able to take an inventory of all aspects of HR or human resources through IEC, namely Communication, Information and Education.
Cipó das almas
Authors: Françoli Yago Daniel , Modena Couto Katia Caroline , Alegria Carrilho Marambio Pedro
Published: August 2022

Trata-se de estudo de caso que sintetiza as principais conclusões de uma pesquisa empírica e qualitativa que teve como objetivo geral analisar as formas da experiência numinosa na vivência do ritual com ayahuasca. Os objetivos específicos foram observar e analisar quais são os símbolos que emergem do ritual e observar aspectos psicológicos a partir de entrevistas. Em relação à metodologia, foram entrevistados três homens, sendo um informante privilegiado e dois participantes de rituais do Santo Daime com ayahuasca, com idades entre 34 e 48 anos. Foi acordado com os dois participantes que elaborassem um desenho, após o ritual com a bebida, para expressarem suas experiências. Já o informante concedeu entrevista para esclarecer pontos não abordados pela literatura e pelo estado da arte dos estudos antropológicos e da psicologia analítica. A abordagem foi do tipo qualitativa e a análise dos resultados foi feita através de categorias analíticas. Em relação à técnica expressiva, foi realizado um estudo de conteúdo a partir do referencial teórico de Jung, Silveira e van Kolck. Nos resultados, atestou-se elementos e símbolos da experiência numinosa, bem como o aprofundamento de vivências centrais para o desenvolvimento e a individuação dos participantes.
Using Voice Biomarkers to Classify Psychological Distress in Adult Helpline Callers: A Retrospective Observational Study (Preprint)
Authors: Iyer Ravi , Nedeljkovic Maja , Meyer Denny
Published: August 2022

BACKGROUND

Elevated psychological distress has demonstrated impacts on individuals’ health. Reliable and efficient ways to detect distress are key to early intervention. Artificial Intelligence has the potential to detect states of emotional distress in an accurate, efficient and timely manner.

OBJECTIVE

To automatically classify short segments of speech obtained from callers to national suicide prevention helpline services, according to low versus high psychological distress, using a range of voice biomarkers in combination with machine learning approaches.

METHODS

One hundred and twenty telephone call recordings were initially converted to 16-bit Pulse Code Modulation format. Short variable length segments of each call were rated on psychological distress using the Distress Thermometer by the responding counsellor and a second team of psychologists blinded to the initial ratings (n=6). Nineteen voice biomarkers were derived from 40ms speech frames within each segment. Candidate biomarkers were reduced using Lasso regression, validated by generalised additive mixed effects regression, accounting for non-linearity, autocorrelation and moderation by sex. Speech frames were then grouped using k-means clustering based on the selected biomarkers. Finally, component-wise gradient boosting was used to classify each speech frame according to low versus high psychological distress. Classification accuracy was confirmed via leave one out cross validation ensuring that speech segments from single callers were not used in both the training and test data.

RESULTS

Using twelve voice biomarkers, 686 of 747 speech segments were successfully classified, AUCROC = 93.8% (95% CI = 91.47, 94.6) and AUCPR = 94.8 (95% CI = 93.0, 96.5). When experiencing elevations in psychological distress, male speakers spoke with increasing loudness, higher frequencies in the 75th percentile of frequencies, but with poorer clarity of speech. In contrast, when experiencing psychological distress, the frequencies with which female callers spoke decreased in the highest quartile of frequencies, but exhibited increased clarity of speech.

CONCLUSIONS

The high level of accuracy achieved suggests possibilities for real-time detection of psychological distress in helpline settings and has potential uses in pre-emptive triage.

CLINICALTRIAL

ANZCTR, ACTRN12622000486729, https://www.anzctr.org.au/ACTRN12622000486729.aspx
Research Into Potential Therapies Against COVID-19, With Focus On Ivermectin (Preprint)
Authors: Rezaie khanghah Reza
Published: August 2022

UNSTRUCTURED

Purpose: Ivermectin is a broad-spectrum antiparasitic and an effective drug to treat COVID-19. In this article, we looked at the effects of ivermectin on coronavirus and its patients in three ways. We have discussed and organized other previously discovered potential therapies and reviewed them in Table 2 and in the last section.
Methods: We searched for articles on MedRxiv, PubMed, Google Scholar, MEDLINE, EMBASE uses the appropriate search terms. ClinicalTrials.gov was searched for available clinical trials evaluating the effectiveness of ivermectin. We also use EU clinical trial registry data and ANZ registry data for clinical trials. Also, we performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results.
Results: Results are variable. Some studies have shown the effectiveness of ivermectin, others have not. Furthermore, some studies show that a combination of ivermectin with other drugs is useful.
Conclusion: Overall, we believe the reason ivermectin is useful is that it goes back to its origin, which is soil. Our theory and hypothesis is that if the coronavirus, created by man or by nature, can generally be treated with nature, that is, the soil. The interesting thing is that today we know that ivermectin is effective in the fight against the coronavirus. In fact, other drugs like teicoplanin, cyclosporine and rapamycin that are effective against the coronavirus have come from the soil. We hope that this article has been able to take a step in finding a corona drug, InshaAllah.
Molecular Evaluation of the Impact of Nd:YAG Laser and Static Magnetic Field on Genomic DNA of Some Bacterial Isolates using RAPD-PCR
Authors: Atiyea Qanat Mahmood , Al-najar Fatima Mustafa , Karim Gulbahar F. , AL-Salihi Siham Sh.
Published: August 2022

Antimicrobial therapy is frequently associated with the emergence of resistant bacteria with a high rate of morbidity and mortality worldwide. The present study was aimed at investigating the impact of a neodymium-doped yttrium aluminum (Nd:YAG) laser, and a static magnetic field (SMF) on cellular growth and DNA alteration in some clinical bacterial isolates. Samples from cutaneous wounds were collected by sterile cotton swabs from three elderly women admitted to Tikrit Teaching Hospital, Tikrit City, Iraq. Isolation and identification of Streptococcus agalactiae, Staphylococcus aureus, and Pseudomonas aeruginosa were carried out using cultural characteristics, microscopy, and biochemical tests. Three broth cultures were prepared for each of the test isolates. The first broth culture served as untreated control, the second was exposed to an Nd:YAG laser and the third was exposed to SMF. Colony counting was done on all the samples. DNA was extracted from the test bacteria and used to perform the RAPD-PCR assay. In contrast to the untreated control, the results showed that Nd:YAG laser radiation was more effective than SMF at inhibiting the cellular growth of the test isolates. Also, the radiation caused DNA alteration, which was established by decreased microbial growth, as well as the development of new bands and the loss of original bands. According to the findings of this study, the Nd:YAG laser is a promising technique for influencing the healing of infected cutaneous wounds. RAPD-PCR is also a useful biomarker assay for assessing the biological impact of laser radiation and SMF on bacteria.
Analysis of Foot and Mouth Disease Virus Polyprotein for Multi Peptides Vaccine Design: An In silico Strategy
Authors: Ahmed Ranya Mohmed Sid , Almofti Yassir A. , Abd-elrahman Khoubieb Ali
Published: August 2022

Foot-and-mouth disease virus (FMDV) is small RNA virus from Picornaviridae family; genus Aphthovirus. FMDV causes maximum levels of infectivity in cattle and harmful socioeconomic effects. The present report attempted to design vaccine candidate from the polyprotein of FMDV to stimulate protective immune response. The IEDB server was used to predict B and T cells epitopes that were linked via GPGPG and YAA linkers, respectively. Mycobacterium tuberculosis 50S ribosomal protein was exploited as an adjuvant and a six histidine-tag sequence was linked to the carboxyl end of the vaccine for purification and identification. The predicted vaccine comprised 313aa and was antigenic and not allergic. Moreover, the vaccine was acidic and showed stability and hydrophilicity. Vaccine secondary and tertiary structures were predicted. The tertiary structure was refined to ameliorate the quality of the global and local structures of the vaccine. Vaccine model validation was performed and the final quality score of the structural model was computed. The validated model was used for molecular docking with bovine (N*01801-BoLA-A11) allele. Docking process in terms of binding free energy score was significant. Vaccine solubility was investigated based on the protein of E. coli and the stability was based on the disulﬁde bonding to lessen the entropic and mobile points in vaccine. Lastly, the in silico cloning ensured the proper cloning and best translation of the DNA of vaccine in molecular vectors.
Mechanism of Microbial Detoxification of Heavy Metals: A Review
Authors: Jayaram Sreevidya , Ayyasamy P.M. , Aiswarya K.P. , Devi M. Prashanthi , Rajakumar S.
Published: August 2022

Heavy metal contamination from anthropogenic activities has an adverse effect on the environment due to its cytotoxicity, carcinogenicity and mutagenicity. Environment harbours microorganisms, some of which have been found to modify physico-chemical conditions of their surrounding environment through certain processes such as detoxification, metal homeostasis, precipitation, redox transformations etc. Investigations in the past have shown that short term contact with metals of certain bacteria causes the selection of resistant bacteria within weeks, while a prolonged exposure showed selected strains able to thrive better. Hence biotic methods could assist removal of heavy metals based on biosorption or bioaccumulation by microorganisms, which are cost-effective and environmental friendly in the long run. Microbial remediation is influenced by biotic and environmental factors as also the contamination site characteristics. The aim of this paper is to highlight and review some of the mechanisms of microbial remediation through techniques such as biostimulation, bioaugmentation etc.
Treatment of MDR Gram-Negative Bacteria Infections: Ongoing and Prospective
Authors: Sharma Mukesh Kumar , Rizvan Moh. , Ahmad Nayeem , Jain Puneet , Kumar Mohan
Published: August 2022

Antimicrobial resistance is a serious public health concern across the world. Gram-negative resistance has propagated over the globe via various methods, the most challenging of which include extended-spectrum β-lactamases, carbapenemases, and AmpC enzymes. Gram-negative bacterial infections are difficult to treat in critically extremely sick persons. Resistance to different antibiotic treatments nearly always lowers the probability of proper empirical coverage, sometimes resulting in severe outcomes. Multidrug resistance can be combated with varying degrees of success using a combination of older drugs with high toxicity levels and novel therapeutics. The current therapies for multidrug-resistant Gram-negative bacteria are discussed in this review, which includes innovative medications, older pharmaceuticals, creative combinations of the two, and therapeutic targets.
Desarrollo de competencias orales para controlar el miedo escénico en los estudiantes de contaduría pública
Authors: Pirela Espina William A.
Published: August 2022

El trabajo tuvo como objetivo describir la importancia de desarrollar competencias orales para controlar el miedo escénico en los estudiantes de contaduría pública. Con una investigación descriptiva de campo, exploratoria y explicativa, realizado con los alumnos inscritos en el período académico 2021 en la licenciatura de contaduría pública de la Escuela de Contaduría Pública de la Facultad de Ciencias Económicas y Sociales de La Universidad del Zulia, Venezuela. Con un muestreo no probabilístico intencionado por conveniencia, se utilizó la encuesta online como técnica de recolección de datos y como instrumento el Cuestionario de Confianza para Hablar en Público, dividido en dos partes: Seguridad. Disfrute al hablar en público y Miedo a hablar en público, estructurado tipo Escala de Likert con una confiabilidad del 0,91 medida a través de la prueba Alfa de Cronbach considerado un coeficiente alto. Los resultados coinciden con anteriores estudios que señalan la relación existente entre el desarrollo de competencias comunicacionales en los estudiantes universitarios y el control del miedo escénico; demostrando la dificultad de los encuestados en el manejo del miedo escénico dado el bajo nivel en el desarrollo de competencias orales, requiriendo cambios en el proceso de enseñanza- aprendizaje a fin de fortalecer sus competencias discursivas.
A Study on the Properties of High Strength Fiber Reinforced Self Curing Concrete
Authors: M Hari Ganesh , G Lavanya
Published: August 2022

Abstract: Curing is the process of maintaining the right moisture level in concrete, especially for the initial 28 days to get the complete cement hydration and the formation of C-S-H gel. The C-S-H gel formation in the concrete is significantly influenced by curing. In most cases, good curing is not practically achievable. Self-curing concrete is one of the unique concretes that aids in reducing inadequate curing caused by human negligence. Self-curing concrete is also used in water-scarce regions. The grade of concrete prepared was M60, and it was tested for its compressive strength, split tensile strength and flexural strength. The cementitious material is partially replaced with silica fume and fly ash by 5% and 10%, respectively. Nylon fiber is also to be introduced in concrete with different ratios like 0.25%, 0.50%, 0.75%, and 1%. This present study aims to determine the most suitable percentage of fiber to be added in high-strength external self-curing concrete so that the loss of strength due to shrinkage crack is reduced and also to improve the impact resistance of the concrete, external self curing compound Concure WB is used in this project for the purpose of curing concrete.
A Statistical Approach to Discriminate the Magnetising Inrush Current and Internal Fault Current of a Transformer
Authors: Bharambe Purushottam R. , Paraskar Dr. Sudhir R , Kankale Ravishankar S. , Jadhao Dr. Saurabh S.
Published: August 2022

Abstract: The transformer is one of the important elements of electrical power system. So, it is required to provide the good protection scheme for transformer, which enhance the reliability & economy of the system. There are many methods available for the protection of transformer out of which differential protection is the most commonly used method. It is observed that the conventional differential protection scheme mal-operates during the magnetizing inrush current. The mal-operation of differential relay will affect the continuity of supply to customer and hence the economy of our system. To avoid such type of mal-operation of the relays, proper discrimination between the magnetising inrush current and fault current is required. This paper presents Teager Energy Operator (TEO) and Statistical parameters based novel approach for the discrimination between the magnetizing inrush current and the internal fault current of a transformer. In this paper, TEO of the differential current of the transformer is calculated and compared with its threshold value to detect the abnormal condition. When TEO is more than threshold, statistical parameters like variance & standard deviation are calculated and if the calculated value is more than the threshold then it’s an internal fault condition and hence relay gives the trip signal. Else relay does not issue the trip signal. The suggested algorithm is tested using the experimental data. The results demonstrated that the suggested algorithms are capable of accurately differentiating between the transformer's internal fault current and inrush current.
Strength Evaluation of High Strength Concrete by Using Fly Ash and Silica Fume as A Partial Replacement of Cement
Authors: Kumar Piyush
Published: August 2022

Abstract: Presently large amounts of fly ash are generated in thermal industries with an important impact on environment as well as humans. In recent years, many researchers have established that the use of supplementary cementitious materials like fly ash (FA), GGBS, blast furnace slag, silica fume, metakaolin, and rice husk ash, hypo sludge etc. can, not only improve the various properties of concrete, but also can contribute to economy in construction costs. This research work describes the feasibility of using Fly ash and Silica Fume as partial replacement of cement. The cement has been replaced by fly ash accordingly in the range of 0%, 10%, 20%, 30%, 40%, 50%, and 60% by weight of cement and 10% of silica fume in common for M30 grade of Concrete. Concrete mixtures produced, tested and compared in terms of compressive strength and split tensile strength with the conventional concrete for 7, and 28 days. It is found that, 30% of fly ash and 10% of silica fume can be replaced and good strength obtained is comparable to the conventional concrete mix.
Identifying Vulnerabilities and Reducing Cyber Risks and Attacks Using a Cyber Security Lab Environment
Authors: Rajeev Gautham. K.
Published: August 2022

Abstract: In the present digital world where everyone is trying to digitalize their data and assets, cyber-attacks and cyber-crimes have made their presence felt much more than when compared to the previous period. During the pandemic days, the number of state sponsored and nation sponsored threat actors who pose the threat of attacking our organizational assets has increased rapidly. Organizations, especially which fall under the critical information infrastructure are becoming an increasingly common target for cyber-attacks. The rate has alarmingly gone up that the national and state government have started to give more attention and focus to cyber security and cyber-crimes. Specific bodies have been assigned by the government to notify about threats/attacks and also to suggest possible techniques to mitigate these threats/attacks. Most devices that are used in these organization are either using older versions of devices or the devices used are not properly cyber secured. This vulnerability is most often taken advantage of by the attacker when trying to access and compromise the organization. Another factor leading to cyber breaches and attacks is the limited or low competency level of employees who work in these organizations. Employees with weak cybersecurity knowledge are the main entry point for online fraud, viruses, and other threats. This creates a situation where business owners and managers should focus on teaching employees the importance of strong digital security. This report describes different techniques and tools which can be used to detect vulnerabilities or threats present in our system, the different cyber-attacks that can take place exploiting these identified vulnerabilities: How to generate an attack, How to identify an attack and How to prevent an attack. Further on, how we can create an environment, where individuals can have hands-on experience on how to detect different cyber threats or vulnerabilities present on a device which makes them confident enough to identify a cyber-attack or threat at an early stage and deploy preventive measures against it is also discussed.
Using Visual Methods to Capture Patient Perspectives in Interprofessional Team-Based Care for Chronic Disease Management
Authors: Sibbald Shannon L , Law Benson , Van Asseldonk Rachelle , Ly Olivia , Licskai Christopher
Published: August 2022

Background: Understanding how patients perceive their role in the healthcare team can improve overall satisfaction of care and health outcomes. However, it has been challenging to capture the diversity of patient experiences using traditional research approaches. The goal of this study was to explore the perspectives of patients involved in an interprofessional team-based chronic disease management program for chronic obstructive pulmonary disease using visual research techniques.
Methods: Our visual approach began with patients autonomously drawing (or mapping) experiences with their healthcare team. The maps were explored with the patients through focus group discussions. Maps were inductively coded to identify similarities and differences between participants’ perceptions. Focus group transcripts were first analyzed independently, then compared to and integrated into the map analysis.
Findings: Overall, participants (n = 13) were satisfied as patients of team-based care. Participants drew multiple healthcare providers, sources of information, and themselves to represent their teams. Relationships and significance were represented using arrows, the size of each team member, facial expressions, and symbols. Four key elements of effective team-based models of care emerged: 1) effective information sharing, 2) diversity of providers’ roles, 3) empowerment through self-management, and 4) enhanced access to care.
Conclusion: This study used visualization methodology to obtain patient feedback on the program’s performance, elicit patients’ experiences, and attempt to mitigate some of the limitations of isolated survey and focus group methodology, subsequently obtaining rich data on team-based care. Our research also informs ongoing quality improvement of the team nbased model for chronic disease management.
Espaço, modernidade e branquitude: notas desde Cidade Ademar (SP)
Authors: Silva Aquiles Coelho
Published: August 2022

Neste artigo intento retomar a noção de espaço e sua construção como categoria moderna orientada pela racialidade, pelos pilares ontoepistemológicos da separabilidade, da determinabilidade e da sequencialidade, pautada em uma pretensão universal. Contraponho o espaço moderno ao espaço-lugar, tal como proposto por Muniz Sodré, para, em meio a essa contraposição, vislumbrar outras possibilidades de compreender e habitar o espaço. Apresento assim o movimento de renovação urbana em curso em Cidade Ademar (SP) enquanto jogo com a afetabilidade como caminho para explorar as frestas que a representação espacial moderna busca ocultar no distrito. Trato, enfim, de apresentar/confrontar o sujeito moderno que se esconde sob o manto da racionalidade e da universalidade, aquele que organiza e se apropria do espaço por ele continuamente nomeado, a fim de desnaturalizar a violência moderna/colonial que suprime outros entendimentos espaciais orientados pela relacionalidade, ou pela afetabilidade.
Pengaruh customer experience dan kualitas pelayanan terhadap keputusan tamu berkunjung kembali ke woobar w bali – seminyak
Authors: Aryanatha Handika
Published: August 2022

W Bali – Seminyak merupakan hotel dengan kategori bintang 5 plus yang cukup dikenal memiliki design yang unik dan sangat berbeda dengan hotel lainnya. W Bali – Seminyak memiliki 1 beach club bernama Woobar. Woobar selalu berusaha memberikan pengalaman dan kualitas pelayanan yang terbaik kepada setiap tamu yang datang berkunjung. Woobar hingga saat ini masih menjadi destinasi yang disukai tamu tetapi seiring berjalannya waktu beberapa tamu merasa bahwa pengalaman yang mereka dapatkan tidaklah sesuai dengan harapan mereka hal ini dibuktikan dari beberapa tanggapan tamu mengenai kualitas pelayanan yang dirasakan ketika Woobar. Penelitian ini bertujuan untuk mengetahui pengaruh customer experience dan kualitas pelayanan secara partial maupun simultam terhadap keputusan tamu berkunjung kembali ke Woobar W Bali – Seminyak. Hasil penelitian menunjukan bahwa terdapat pengaruh antara customer experience (X1), dan kualitas pelayanan (X2) secara bersama-sama dengan nilai signifikansi 0,000 < 0,05 dimana customer experience dan kualitas pelayanan secara bersama-sama mempengaruhi keputusan berkunjung sebesar 89.4%, sedangkan selebihnya yaitu 10.6% merupakan keputusan berkunjung konsumen yang dipengaruhi faktor-faktor lain yang tidak diteliti. Dari uji yang dilakukan secara partial, diketahui tidak terdapat pengaruh positif antara customer experience terhadap keputusan berkunjung tamu di W Bali – Seminyak dengan hasil nilai signifikansi 0.879 > 0.05 dan terdapat pengaruh positif antara kualitas pelayanan terhadap keputusan berkunjung tamu ke W Bali – Seminyak dengan perhitungan nilai signifikansi 0.000 < 0.05.
CT Angiographic Study on the Variations of the Hepatic Arteries in the Living Liver Donors of the South Indian Population.
Authors: Ashok P , Raghunath Gunapriya , Anantha Kumari V , Shiny Vinila B. H
Published: August 2022

Living liver donor transplantation is the last option for the end stage liver diseases. The variations in the hepatic artery of the liver donor may lead to poor outcome, or may end with major post-operative complications such as hepatic artery thrombosis. To prevent the post-operative complications and to increase the success rate of the liver transplant surgeries, CT evaluation of the hepatic arteries is essential. Thus, the present study was aimed to study the variations of the hepatic arteries in the living liver donors. A total of 200 CT angiograms were collected from the department of Radiology from August 2018 to December 2021, and the evaluation was carried out in the Department of Anatomy, Deccan College of Medical Sciences, Hyderabad. All the CT angiograms were studied for the variations of hepatic arterial system, and the observed variations were noted and the incidence was calculated. The normal anatomy was observed in 62.5% liver donors and 37.55% of liver donors showed variations in hepatic arterial pattern. The incidence of the replaced left hepatic retry, replaced right artery, replaced left along with replaced right hepatic artery was observed as 11.5%, 9.5% and 3% respectively. The incidence of left and right accessory hepatic arteries was 7% and 4% respectively and the replaced right hepatic artery with accessory left hepatic artery was observed in 1.5% cases. The variations observed in the hepatic arterial pattern observed in this study could be helpful to the surgeons, while planning and selecting the suitable liver donors and also may minimise the risk and increase the success rate.Â
Effect of Visual Evoked Potentials in Patients with Primary Hypertension
Authors: Joseph Jalsi , Joseph Danti , Bennet Abraham Sam Jefferson
Published: August 2022

Hypertension can cause vascular endothelial changes which can lead to hyalinization and demyelination. It also causes hypertensive retinopathy and retinal artery atrophy in chronic hypertensive patients. Retinal artery atrophy can lead to demyelination changes in the optic nerve. Visual evoked potentials (VEPs) can be used as a sensitive method for documenting the abnormalities in the visual pathways. VEPs are electrical potential differences recorded from the scalp to the visual stimuli. The demyelination changes of optic nerve in early stages of primary hypertension were not studied much. Hence, this study was aimed to assess the effect of VEP in primary hypertension. The main objective of this study was to correlate the latency and amplitude of VEPs in normal individuals and primary hypertensive patients. This is a comparative study which was done between two groups. Group A was a control group with 60 normal participants and group B was a study group that had 60 primary hypertensive patients. Pattern reversal VEP (Parameters – N75, P100 & N145 latencies and amplitude of P100) was recorded in both groups. The variables were correlated between group A and group B. In the result of this study, the VEP latencies of N75 and P100 waves was increased (duration delayed) significantly in both right eye and left eye of participants in Group B than Group A. Amplitude of P100 wave was decreased in both eye, but it is not statistically significant in left eye. VEP parameters can be used for routine screening and diagnostic tests for visual impairment and hypertensive retinopathy even in earlier stages of hypertensive patients.
MDR Isolates Virulence of DNase activity Identified Staphylococcus and Pseudomonas Species from Diabetic Foot Ulcer
Authors: Venkatesan Ramasamy , S.S Raja Suresh
Published: August 2022

Diabetes mellitus is the leading cause of death and morbidity from long-term consequences. Antibiotic resistance is the most common treatment for diabetic foot ulcers. Chronic wounds are caused by antibiotic misuse, mistreatment of medications, and a reduction in the effectiveness of effective antibiotics in the wound or infection environment. Chemical suppression of bacterial intercellular communication, particularly quorum sensing, is of particular relevance in this regard because it regulates pathogenicity in many therapeutically relevant infections where resistance to antibiotics is a challenge. Resistance genes are also acquired through the interchange of bacterial plasmids and chromosomal. Our aim and objective is to microbiological culture study for the clinical pus samples of foot diabetic patients. Our study comprised 131 samples from diabetic foot ulcer patients, with male patients providing for 59% and female patients accounting for 41%. In 131 sample progressing reports, 81 isolates were discovered, ranging in age from 40 to 80 years. The most commonly infected age groups are 51 to 60, with the majority of infection cases categorized as grade III. A sample was taken. The sample grew 97 percent of the time and grew just 3% of the time, with mono microbial growth 48 percent of the time and poly microbial growth 49 percent of the time. MDR Gram positive staphylococci 14 isolates and gram negative pseudomonas 11 isolates showed resistance to 25 culture DNase enzyme activity. In staphylococci 9 isolates and pseudomonas 6 isolates, the DNase enzyme activity in DNase agar media light zone formed. In conclusion diabetic foot ulcers are one of the most prevalent, expensive, and serious consequences of diabetes, and they are considered a major public health issue. Early diagnosis and successful therapy require accurate identification of the causative microorganisms.