bluuebunny/crossref_metadata_2025 huggingface dataset:
Computation of Polynomial Degree-Based Topological Descriptors of Indu-Bala Product of Two Paths
Authors: Abbas Ghazanfar , Ibrahim Muhammad
Published: November 2021

Cheminformatics is entirely a newly coined term that encompasses a field that includes engineering computer sciences along with basic sciences. As we all know, vertices and edges form a network whereas vertex and its degrees contribute to joining edges. The degree of vertex is very much dependent on a reasonable proportion of network properties. There is no doubt that a network has to have a reliance of different kinds of hub buses, serials, and other connecting points to constitute a system that is the backbone of cheminformatics. The Indu-Bala product of two graphs

G

1

and

G

2

has a special notation as described in Section 2. The attainment of this product is very much due to related vertices at to different places of

G

1

∨

G

2

. This study states we have found M-polynomial and degree-based topological indices for Indu-Bala product of two paths

P

k

and

P

j

for

j
,
k
≥
2

. We also give some graphical representation of these indices and analyzed them graphically.
Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma
Authors: Wang Xiang-Ming , Chen Shang-Wei , Chen Gang , Zhou Hua-Fu , Gan Ting-Qing , Zeng Jing-Jing , Li Zu-Yun
Published: November 2021

This study is aimed at thoroughly exploring the expression status, clinical significance, and underlying molecular mechanism of miRNA-33a-5p in lung squamous cell carcinoma (LUSC). Here, we detected miRNA-33a-5p in 20 samples from patients with LUSCs and 20 matching non-LUSC specimens by in-house quantitative real-time PCR (RT-qPCR). Relationship between miRNA-33a-5p expression and clinicopathological traits was investigated from materials derived from miRNA sequencing and miRNA microarrays. A pool standard mean difference (SMD) and summary receiver operating characteristic curves (SROC) were calculated to evaluate the integrated expression value of miRNA-33a-5p in LUSC. Twelve online platforms were applied to select potential target genes of miRNA-33a-5p. The differentially expressed genes (DEGs) of LUSC and the candidate target genes of miRNA-33a-5p were overlapped to acquire a set of specific genes for further analyses of the Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and protein–protein interaction (PPI) network. miRNA-33a-5p overexpressed in LUSC was supported by 706 LUSC and 261 non-LUSC samples gathering from RT-qPCR, miRNA-seq, and public miRNA microarrays. The pooled SMD was 0.56 (95% CI: -0.01-1.05), and the area under the curve (AUC) of the SROC was 0.78 (95% CI: 0.74-0.82). A total of 240 genes were identified as potential target genes of miRNA-33a-5p for functional enrichment analyses; the results suggested that these target genes may participate in several vital biological processes that promote the proliferation and progression of LUSC. miRNA-33a-5p may play an essential role in the occurrence and development of LUSC by targeting hub genes (ETS1, EDNRB, CYR61, and LRRK2) derived from the PPI network. In summary, our results indicated that miRNA-33a-5p may contribute as a prospective therapeutic target in LUSC.
Correlation between Breast Ultrasound Microcalcification and the Prognosis of Breast Cancer
Authors: Xue Shanshan , Zhao Qiaoling , Tai Minghui , Li Ning , Liu Yun
Published: November 2021

Breast cancer is a common gynecological disease, and its incidence and mortality are higher than those of other common malignant tumors. Breast ultrasound technology is a new surgical method, which has the advantages of reducing postoperative complications, improving the quality of life of patients, and improving the prognosis of patients. Breast microcalcification is a new method for the treatment of tumors. Its mechanism is that the proliferation of breast cancer cell walls increases the inflammatory factors in the cancer tissues and enhances the formation of tumors and peripheral vascular thrombosis. Breast microcalcification in the treatment of breast cancer patients will have a more significant impact compared to ordinary antibiotics alone. For this reason, the microcalcification performance of breast ultrasound is worthy of study, and related research on prognosis is also indispensable. The purpose of this study is to improve the understanding of the ultrasound manifestations of breast cancer microcalcification and the prognosis of breast cancer. This article mainly applied statistical analysis as well as experimental and survey methods to conduct breast ultrasound examination on 100 patients and analyzed the ultrasound manifestations of breast cancer MCs from three aspects: location, shape, and distribution. The experimental results show that there is no correlation between the location and distribution of breast cancer MCs and the diameter of the cancer foci, but there is a certain correlation between the morphology (non-gravel-like calcification) and the diameter of the cancer foci (>5 cm). Among them, HER-2 overexpression accounted for 11.9% in the grit-like MCs group and 51% in the non-grit-like MCs group.
Establishment of Normal Range for Thromboelastography in Healthy Middle-Aged and Elderly People of Weihai in China
Authors: Ni Lina , Xue Peng , An Changjuan , Yu Xia , Qu Jiangli , Yao Yingjie , Li Yingbo
Published: November 2021

TEG can monitor the dynamic changes of blood clot formation and lysis by activating the coagulation system of a small sample of whole blood in vitro. The parameters can reflect the level of coagulation factors, the function of fibrinogen and platelet, and the presence or absence of hyperfibrinolysis. At present, the normal reference range of the parameters of TEG is mainly based on the reference values established by the Western population. Due to the differences in the distribution of ethnic groups, many countries have established their reference ranges for healthy populations. In China, some scholars have tried to establish the corresponding TEG reference range according to the characteristics of the population in different regions. This study tried to establish the reference range for thromboelastography in healthy middle-aged and elderly people of Weihai in China and compare it with the reference range provided by the manufacturer. The fasting venous blood of 454 healthy middle-aged and elderly people was collected, including 239 males and 215 females. The thromboelastography TEG-5000 was used to measure the reaction time (R), coagulation formation time (K), coagulation angle (Angle), and maximum amplitude (MA). The reference range of TEG parameters of middle-aged and elderly healthy males was R: 4.38–8.27 min, K: 1.44–2.82 min, Angle: 48.53–72.17 deg, and MA: 51.95–72.02 mm; respectively, in the females, the normal value was R: 3.43–7.40 min, K: 1.07–2.53 min, Angle: 48.22–77.22 deg, and MA: 53.10–74.58 mm; The difference of R, K, Angle, and MA between the male group and the female group was statistically significant (

P

 < 0.05); In this study, if we use the reference range established by the manufacturer, the R specificity for males was 91.6%, K specificity was 98.7%, Angle specificity was 85.8%, and MA specificity was 93.7%; the range for females was 68.4%, 99.5%, 75.8%, and 87.4%, respectively. There are statistically significant differences between R, K, Angle, and MA in middle-aged and elderly healthy women and men. It is necessary to establish a TEG reference range for healthy females and males.
Cross Product and Partitioned Filtering-Based Graham Convex Hull for Buoy Drifting Area Demarcating
Authors: Xue Han , Zhang Weicheng , Ni Chao , Lu Xiping
Published: November 2021

An improved Graham scan convex hull algorithm is designed using the convex hull region shrinkage algorithm and the sample selection decision algorithm. In the sorting of Graham scan convex hull algorithm, the cross-multiplication method is used instead of the operation of finding the polar angle, which avoids the high computational complexity of finding the inverse trigonometric function. When the polar angles are the same, that is, the two points are collinear, the points close to each other are deleted directly. Select the maximal horizontal ordinate point, minimal horizontal ordinate point, maximal longitudinal coordinate point, and minimal longitudinal coordinate point. Connect these points and obtain lines. The whole plane is divided into different regions. The points that are not on the convex hull are deleted, and the redundant points are removed. This can speed up the calculation of approximate convex hull boundary and shorten the time of convex hull calculation. The proposed algorithm is used for buoy drifting area demarcating. The offsets of the geometric center of the high-frequency position point and the distance from geometric center of high-frequency position of buoy to sinking stone are calculated. The experimental results show that the new algorithm can effectively accelerate the convex hull calculation. We use the convex hull process to compute the area of the drifting buoy position and discover that the drift area of the port hand buoy is similar. The drift area of the port hand buoys is similar. The drift area of the port hand buoy is greater than that of the port hand buoy.
Recognition of Power Equipment Based on Multitask Sparse Representation
Authors: Lei Lei , Wu Jian , Zheng Shuhai , Zhang Xinyi , Wang Liang , Wang Yanfei , Wan Hao
Published: November 2021

Image analysis of power equipment has important practical significance for power-line inspection and maintenance. This paper proposes an image recognition method for power equipment based on multitask sparse representation. In the feature extraction stage, based on the two-dimensional (2D) random projection algorithm, multiple projection matrices are constructed to obtain the multilevel features of the image. In the classification process, considering that the image acquisition process will inevitably be affected by factors such as light conditions and noise interference, the proposed method uses the multitask compressive sensing algorithm (MtCS) to jointly represent multiple feature vectors to improve the accuracy and robustness of reconstruction. In the experiment, the images of three types of typical power equipment of insulators, transformers, and circuit breakers are classified. The correct recognition rate of the proposed method reaches 94.32%. In addition, the proposed method can maintain strong robustness under the conditions of noise interference and partial occlusion, which further verifies its effectiveness.
MEA‐CNDP: A Membrane Evolutionary Algorithm for Solving Biobjective Critical Node Detection Problem
Authors: Xu Yaochang , Guo Ping
Published: November 2021

The critical node detection problem (CNDP) refers to the identification of one or more nodes that have a significant impact on the entire complex network according to the importance of each node in a complex network. Most methods consider the CNDP as a single‐objective optimization problem, which requires more prior knowledge to a certain extent. This paper proposes a membrane evolution algorithm MEA‐CNDP to solve biobjective CNDP. MEA‐CNDP includes a population initialization strategy based on the evaluation of decision variables, a strategy to transform the main objective, a strategy to update the membrane inherited pool, and four membrane evolutionary operators. The numerical experiments on 16 benchmark problems with random and logarithmic weights show that MEA‐CNDP outperforms other algorithms in most cases. In particular, MEA‐CNDP has unique advantages in dealing with large‐scale sparse bi‐CNDP.
The Core‐Periphery Structure in the Yangtze River Delta: An Enterprise Linkage Perspective, 1978–2019
Authors: Yang Jieying , Zhang Jingxiang , Lu Jiayi , Sun Dongqi
Published: November 2021

Metropolitan areas are important for engaging in fierce global competition. Cities in metropolitan areas in China are generally characterized by a core‐periphery structure. The Yangtze River Delta metropolitan area (YRD) is a national strategic region in which Shanghai, as a central city, drives the economic growth of hinterland cities. Exploring the spatiotemporal characteristics and influencing factors between the central city and its hinterland cities in the YRD can provide a basis for promoting regional development. Based on the headquarters‐branches and enterprise investment data from 1978 to 2019, this study analyzes the spatiotemporal characteristics and influencing factors of enterprise linkages between Shanghai and its hinterland cities in the YRD. Our results reveal the following: (1) the headquarters‐branch linkages between Shanghai and its hinterland cities manifest polarization characteristics, with different polarized characteristics among the three provinces; (2) the enterprise investment linkages between Shanghai and its hinterland cities are getting closer, but the key cities for investment in each province are different; (3) economic strength is a core factor that affects whether Shanghai establishes enterprise branches in its hinterland cities; and (4) the enterprise investment linkages between Shanghai and its hinterland cities depend on whether a city has a comparative advantage.
WEB DDoS Attack Detection Method Based on Semisupervised Learning
Authors: Yu Xiang , Yu Wenchao , Li Shudong , Yang Xianfei , Chen Ying , Lu Hui
Published: November 2021

Since the services on the Internet are becoming increasingly abundant, all walks of life are inextricably linked with the Internet. Simultaneously, the Internet’s WEB attacks have never stopped. Relative to other common WEB attacks, WEB DDoS (distributed denial of service) will cause serious damage to the availability of the target network or system resources in a short period of time. At present, most researches are centered around machine learning-related DDoS attack detection algorithms. According to previous studies, unsupervised methods generally have a high false positive rate, while supervisory methods cannot handle large amount of network traffic data, and the performance is often limited by noise and irrelevant data. Therefore, this paper proposes a semisupervised learning detection model combining spectral clustering and random forest to detect the DDoS attack of the WEB application layer and compares it with other existing detection schemes to verify the semisupervised learning model proposed in this paper. While ensuring a low false positive rate, there is a certain improvement in the detection rate, which is more suitable for the WEB application layer DDoS attack detection.
Study of Heat Transfer in Magnesium Zinc Zirconium

MgZn

6

Zr
Alloy Suspended in Engine Oil
Authors: Noor Saima , Mukhtar Safyan
Published: November 2021

In this paper, alloy nanoparticle

MgZn

6

Zr

will be analyzed for the first time in the flow of ferromagnetic nanofluid. The combination of two or more metallic substances is termed as alloy. In other words, alloys are a solid solution or mixture of more than one metallic substance. Thus, alloys have always distinct melting points. This means that alloys have melting ranges instead of melting points. Due to these characteristics, alloy nanoparticles are efficient for heat transfer in liquid flows. Thus, we will consider magnesium alloy

MgZn

6

Zr

which is suspended in the base fluid engine oil C8H18. The suspension will be analyzed along a dipole; thus, the fluid is known as ferromagnetic

MgZn

6

Zr
−

C

8

H

18

nanofluid. Solutions will be obtained numerically through the RK-method (shooting method). Our motivation is to optimize the heat transfer through the parametric study. Further, velocity of the fluid is observed to be decreasing with increasing the volume fraction of nanoparticles while temperature profile gets a rise with increase in volume fraction. Moreover, the presence of alloys in any viscous base fluid can decline the fraction between certain fluid layers which results in fast velocity field for the proposed fluid.
First-in-human HER2-targeted Bispecific Antibody KN026 for the Treatment of Patients with HER2-positive Metastatic Breast Cancer: Results from a Phase I Study
Authors: Zhang Jian , Ji Dongmei , Cai Li , Yao Herui , Yan Min , Wang Xiaojia , Shen Weina , Du Yiqun , Pang Hui , Lai Xiuping , Zeng Huiai , Huang Jian , Sun Yan , Peng Xinxin , Xu Junfang , Yang Jing , Yang Fei , Xu Ting , Hu Xichun
Published: November 2021

Purpose:

KN026 is a novel bispecific antibody that simultaneously binds to two distinct HER2 epitopes. This first-in-human phase I study evaluated the safety/tolerability, pharmacokinetics, preliminary efficacy, and potential predictive biomarker activity of KN026 administered as monotherapy to patients with HER2-positive metastatic breast cancer (MBC).

Patients and Methods:

Female patients with HER2-positive MBC who had progressed on prior anti HER2 therapies received intravenous KN026 monotherapy at 5 mg/kg (once weekly), 10 mg/kg (once weekly), 20 mg/kg (once every 2 weeks), or 30 mg/kg (once every 3 weeks). Dose escalation was guided by a “3+3” dose escalation rule followed by dose expansion.

Results:

Sixty-three patients were enrolled. The most common treatment-related adverse events (TRAE) were pyrexia (23.8%), diarrhea (22.2%), aspartate aminotransferase increased (22.2%), alanine aminotransferase increased (22.2%). Only 4 patients reported grade 3 TRAEs. Results from exposure-response analysis supported the selection of the recommended phase II doses at 20 mg/kg once every 2 weeks or 30 mg/kg once every 3 weeks, which had objective response rates (ORR) of 28.1% and median progression-free survival (PFS) of 6.8 months (95% confidence interval: 4.2–8.3) in 57 patients. Translational research in 20 HER2-amplified patients further confirmed that co-amplification (vs. no co-amplification) of CDK12 was a promising biomarker in predicting better response to KN026 (ORR of 50% vs. 0% and median PFS of 8.2 vs. 2.7 months, P = 0.05 and 0.04, respectively).

Conclusions:

KN026, a HER2 bispecific antibody, was well tolerated and achieved comparable efficacy as trastuzumab and pertuzumab doublet even in the more heavily pretreated patients. Co-amplification of HER2/CDK12 may define patients who benefit more from KN026.
O que é ativismo curatorial?
Authors: Reilly Maura , Avelar Ana , Imparato Marcella
Published: November 2021

Tradução do primeiro capítulo do livro Curatorial Activism: Towards an Ethics of Curating (Thames & Hudson, 2018), de Maura Reilly.
A geopolítica dos mundos da arte ocidental: reflexão e metodologia
Authors: Dossin Catherine
Published: November 2021

Em uma reflexão sobre as origens e a metodologia do seu livro The Rise and Fall of American Art, 19840s-1980s: A Geopolitics of the Western Art Worlds (2015), Catherine Dossin reposiciona seu trabalho em um contexto de crescente atenção às múltiplas histórias da arte, no qual se faz necessário confrontar tal desafio metodológico. A autora então discute a geopolítica como um modelo útil para se pensar a complexa historiografia da arte do pós-guerra, abordar a polifonia de discursos desse período e analisar as dinâmicas de poder e os mecanismos históricos que garantem a alguns de seus capítulos o estatuto de história.
Entre a ruína e o canteiro: José Resende na Mooca
Authors: Corrêa Patricia
Published: November 2021

Em 2012, o artista José Resende, em colaboração com o filósofo Nelson Brissac e a engenheira Heloísa Maringoni, propôs uma intervenção no bairro da Mooca, no centro da cidade de São Paulo, em pleno processo de reestruturação urbana e gentrificação. Porém, sua proposta Canteiro de Operações não pôde se realizar e levou a duas outras propostas de intervenções que se realizaram sob o mesmo nome. Este texto assume a tarefa de contar a história do que aconteceu e do que não aconteceu, elaborando a sua trama de tempos entre fracassos e potencialidades, experiências e expectativas, ou entre a reivindicação crítica de um passado e a imaginação de possibilidades de futuro. Ou, ainda, entre a ruína e o canteiro.
Cuidar de borboletas: uma origem terapêutica para a prática da História da Arte
Authors: Cabañas Kaira M.
Published: November 2021

O presente artigo propõe uma maneira alternativa de mapear a história da arte, uma maneira que acolhe as histórias adjacentes frequentemente consideradas exteriores à linha “apropriada” de pesquisa nesse campo. Para tal cartografia alternativa, me volto para uma figura fundadora da história da arte ocidental, Aby Warburg. Para isso, trato do caso clínico de Warburg e busco, com isso, pôr em relevo as interseções do crítico e do clínico no cerne de sua vida e de sua prática intelectual, bem como as sobrevivências de cada uma dessas atividades. Ao fazê-lo, proponho uma resposta possível para a pergunta: será que a prática da história da arte poderia ter efeitos terapêuticos?
Alfredo Jaar e o desejo de inventar novos modelos de pensar o mundo: América x América Latina
Authors: Couto Maria de Fátima Morethy
Published: November 2021

A partir do trabalho A Logo for America e de outros projetos de autoria do artista chileno Alfredo Jaar, este artigo visa refletir sobre os variados usos dos termos América e América Latina e suas múltiplas possibilidades de representação, enfatizando as conexões existentes entre divisões geopolíticas e interesses econômicos.
“The World Was Given Us to Fix It”
Authors: Koplowitz-Breier Anat
Published: November 2021

This article explores the ecopoetry written by three women poets who also identify themselves as Jewish poets: Alicia Ostriker, Marge Piercy and Naomi Ruth Lowinsky. It examines whether they employ any or some/all of the “emancipatory strategies” characteristic of the ecofeminist re-imagination of nature and human relationships with the natural world, seeking to answer several questions: How far can these poems be considered part of eco-Judaism? Does the fact that their authors are women also make them ecofeminist works? Does the poets’ Jewish feminist identity contribute to their ecopoetic call for ecological change?
The Promise of Jewish Theistic Naturalism for Jewish Environmental Ethics
Authors: Guzi Bar
Published: November 2021

This paper seeks to explain the greater appeal of Jewish naturalistic theologies given our greater appreciation today of the ecological vulnerability of our world. By examining the theological writings of two prominent twentieth-century Jewish thinkers—Hans Jonas and Arthur Green. The paper demonstrates that their espousal of naturalistic yet theistic worldview in their interpretations and reconstructions of Jewish tradition shares significant affinities and promotes an ethical attitude toward the environment. First, I show that Jonas and Green reject reductive forms of naturalism and embrace a nonreductive or “expansive” style of naturalism. Then, I argue that their theologies intend to stimulate a sense of responsibility toward all creation by envisioning humans as partners of a non-omnipotent God. I conclude by noting the metaphysical, epistemological, and moral promises of theistic naturalism to Jewish environmental ethics.
Frenemies: Overcoming Audiences’ Ideological Opposition to Firm–Activist Collaborations
Authors: Odziemkowska Kate
Published: November 2021

Collaborations between organizations from different sectors, such as those between firms and nonprofits or governments, can offer effective solutions to complex societal problems like climate change. But complications arise because organizations operating in different sectors rely on the approval of different audiences, who may not view these relationships positively, for resources and survival. I show how concerns about audience approval impede cross-sector collaborations forming between firms and social movement organizations (SMOs) despite their potential societal benefits. Firms wanting to signal their efforts in support of a movement’s cause may be eager to form collaborations with SMOs. But when SMOs’ supporters and/or peers define their identity in opposition to firms—when they are oppositional audiences—collaborations do not form. I argue and find that SMOs who cooperate, and don’t compete, with oppositional peers can better navigate the constraint of oppositional audiences. Firms, in contrast, aggravate the constraint of oppositional audiences. Firms’ inclination to seek collaborations to repair their reputations with their own audiences after being contentiously targeted by a movement compounds the challenge to SMOs of partnering with the enemies of their friends. My arguments on countervailing audience effects stifling collaborations are corroborated in 25 years of data on interactions between SMOs in multiple environmental movements and Fortune 500 firms.
Increased Mortality in Hip Fracture Patients With Aortic Stenosis and Pulmonary Hypertension Compared to Aortic Stenosis Alone
Authors: Cignoni Christian B. , Vuu Steven K. M. , Liu Huazhi , Clark Jason M. , Watson Carrie D. , Ferber Laurence R. , Richards Winston T. , Ang Darwin N.
Published: November 2021

Introduction

Hip fractures are one of the most common traumatic injuries in the United States, secondary to an aging population. Multiple comorbidities are found in patients who present to trauma centers (TCs) with isolated hip fractures (IHFs) including significant cardiac disease. Aortic stenosis (AS) among these patients has been recently shown to increase mortality. However, factors leading to death from AS are unknown. We hypothesize that pulmonary hypertension (PH) is a significant mechanism of death among IHF patients with AS.

Methods

This is a multicenter retrospective cohort study examining IHF patients treated at Level I and II TCs within a large hospital system from 2015 to 2019. Patients who had IHFs and AS were compared to those who had IHFs, AS, and PH. Multivariable logistic regression was used to risk adjust by age, race, insurance status, and comorbidities. The primary outcome was inpatient mortality. The secondary outcomes were hospital-acquired complications.

Results

A total of 1388 IHF patients with AS were included in the study. Eleven percent of these patients also had PH. The crude mortality rate was higher if IHF patients had both AS and PH compared to IHF with AS alone (9% vs 3.7%, P-value .003). After risk adjustment, a higher risk of mortality was still significant (aOR 2.56 [95% CI 1.28, 5.11]). In addition, IHF patients with both AS and PH had higher complication rates; the exposure group had higher percentage of pulmonary embolism (1.4% vs .2%, adjusted P-value .03), new-onset congestive heart failure (4.1% vs 1%, adjusted P-value .01), and sepsis/septicemia (3.5% vs 1.4%, adjusted P-value .05).

Conclusion

In patients with IHFs, PH and AS increase the likelihood of inpatient mortality by 2.5 times compared to AS alone. Pulmonary hypertension among IHF patients with AS is an important risk factor to identify in the preoperative period. Early identification may lead to better perioperative management and counseling of patients at higher risk of complications.
The Impact of Flame Burn Injuries on Patients Who Sustain Mild Injuries From Motor Vehicle Crashes
Authors: Campbell Brady A. , Rozycki Grace F. , Haut Elliott R. , Fang Raymond , Hultman Charles Scott
Published: November 2021

Background

The purpose of this study was to determine the differences in patient outcomes between motor vehicle crash (MVC) victims with an ISS < 15 and those with a similar ISS and a flame burn injury.

Methods

Data for patients involved in a MVC with a GCS ≥12 and an ISS < 15 with and without flame burn injury were reviewed from the American College of Surgeons National Trauma Data Bank between 2007 and 2017. International Classification of Diseases-9 and -10 revisions and External Injury Codes were used to identify patients who were divided into MVC only (Group 1) and MVC with additional flame burn injury (Group 2). In-hospital mortality was the primary outcome whereas secondary outcomes included ICU admission, ICU length of stay (LOS), hospital LOS, sepsis, deep vein thrombosis, acute respiratory distress syndrome, and pneumonia. Simple linear regression was used in the form of odds ratios to investigate risk factors for mortality and secondary outcomes.

Results

The mean LOS and ICU LOS were longer in Group 2 (5.9 vs 4.0 days, p-value <0.001, and 1.2 vs 0.6 days, p-value <0.001, respectively), with more patients being admitted to the ICU as well (22.9% vs 17.3%, p-value <0.001). Also, there were significantly higher rates of pneumonia (0.8% vs 0.5%, p-value 0.0014), deep vein thrombosis (0.6% vs 0.4%, p-value 0.028), and acute respiratory distress syndrome (0.5% vs 0.3%, p-value 0.004) in Group 2. Patients in Group 1 were older and more likely had hypertension, congestive heart failure, and COPD. There was no significant difference in mortality between Groups by odds ratios (OR 0.85, p-value 0.743) or raw percentages (0.3% vs 0.3%, p-value = 0.874).

Conclusion

MVC victims with mild injuries who also sustain a burn injury are more likely to require admission to the ICU regardless of their comorbidities and more likely to develop respiratory complications, especially pneumonia and an increase in ICU and hospital LOS.
Clinical and Microbiological Factors Associated With Abscess Formation in Adult Acute Epiglottitis
Authors: Sideris Giorgos , Papadimitriou Nikolaos , Korres Georgios F. , Karaganis Anastasios , Maragkoudakis Pavlos , Nikolopoulos Thomas , Delides Alexander
Published: November 2021

Objectives:

To evaluate clinical and microbiological findings that are correlated with abscess formation in adult acute epiglottitis (AE).

Methods:

We reviewed 140 cases of adult AE. Demographic, clinical, imaging, and microbiological findings are analyzed for all patients with AE in comparison to those with epiglottic abscess (EA).

Results:

A total of 113 patients presented with AE and 27 presented or progressed to EA (19.3%). Age, sex, seasonality, smoking, body mass index (BMI), and comorbidities were statistically insignificant between the 2 groups. Muffled voice ( P < .013), respiratory distress ( P < .001), and pre-existence of epiglottic cyst ( P < .001) are symptoms and signs connected with abscess formation. A total of 120 patients were treated conservatively. Surgical treatment was performed on 20 patients with EA. About 72 out of 80 cultures revealed monomicrobial infection. Mixed flora was isolated in 8 patients with EA. Streptococcus was isolated in 51 out of 80 positive cultures (64%). Haemophilus Influenza ( Hib) was not isolated in any sample. EA and mixed flora relates to a higher rate of airway intervention ( P < .001).

Conclusion:

A high level of suspicion for abscess formation is required if clinical examination reveals dyspnea, muffled voice, or an epiglottic cyst in adult with AE. The existence of EA doubles the duration of hospitalization. EA is typically found on the lingual surface of the epiglottis. Supraglottic or deep neck space expansion should be treated surgically. EA is associated with a mixed flora and a higher rate of airway obstruction. Streptococcus is discovered to be the most common pathogen.
Major depression as a predictor of the intergenerational transmission of attachment security: Findings from a pregnancy cohort study
Authors: Galbally Megan , Watson Stuart J , Tharner Anne , Luijk Maartje , Blankley Gaynor , MacMillan Kelli K , Power Josephine , Lewis Andrew J
Published: November 2021

Objective:

Understanding the relationship between attachment and mental health has an important role in informing management of perinatal mental disorders and for infant mental health. It has been suggested that experiences of attachment are transmitted from one generation to the next. Maternal sensitivity has been proposed as a mediator, although findings have not been as strong as hypothesised. A meta-analysis suggested that this intergenerational transmission of attachment may vary across populations with lower concordance between parent and infant attachment classifications in clinical compared to community samples. However, no previous study has examined major depression and adult attachment in pregnancy as predictors of infant–parent attachment classification at 12 months postpartum.

Methods:

Data were obtained on 52 first-time mothers recruited in early pregnancy, which included 22 women who met diagnostic criteria for current major depression using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders. The Adult Attachment Interview was also administered before 20 weeks of pregnancy. A history of early trauma was measured using the Childhood Trauma Questionnaire and maternal sensitivity was measured at 6 months postpartum using the observational measure of the Emotional Availability Scales. Infant–parent attachment was measured using the Strange Situation Procedure at 12 months.

Results:

Overall, we found no significant association between the Adult Attachment Interview and the Strange Situation Procedure classifications. However, a combination of maternal non-autonomous attachment on the Adult Attachment Interview and major depression was a significant predictor of insecure attachment on the Strange Situation Procedure. We did not find that maternal sensitivity mediated parental and infant attachment security in this sample.

Conclusion:

While previous meta-analyses identified lower concordance in clinical samples, our findings suggest women with major depression and non-autonomous attachment have a greater concordance with insecure attachment on the Strange Situation Procedure. These findings can guide future research and suggest a focus on depression in pregnancy may be important for subsequent infant attachment.
Are They Really a New Species? Exploring the Emergence of Social Entrepreneurs Through Giddens’s Structuration Theory
Authors: Steiner Artur , Jack Sarah , Farmer Jane , Steinerowska-Streb Izabella
Published: November 2021

Using Giddens’s structuration theory and empirical data from a study with social enterprise stakeholders, the article explores how social entrepreneurs and the structure co-create one another. We show that the development of the contemporary significance of social entrepreneurialism lies in a combination of complex context-specific structural forces and the activities of agents who initiate, demand, and impose change. Social entrepreneurs intentionally tackle social challenges, but their actions bring unintentional results, such as the transfer of state responsibilities onto communities. Direct outputs of their activities introduce indirect outcomes, bringing wider changes in culture and policy. The evolving nature of entrepreneurship and a number of factors that interplay in time and space, and enable and constrain social entrepreneurs, confirm the applicability of Giddens’s theory in the field of social entrepreneurship. The originality of this article derives from revealing mechanisms that enable social entrepreneurs to emerge and reasons for structural change. We also build a “co-creation model of structure and agency” that can be used to “engineer” the process of social entrepreneurship.
How Conceptions of Equity Inform Principal Data Use: A Purposeful Examination of Principals From Four School Districts
Authors: Roegman Rachel , Perkins-Williams Ruqayyah , Budzyn Matt , Killian-Tarr Olivia , Allen David
Published: November 2021

In this study, we examine principals’ data use within four districts are engaged in district-level professional learning around equity. Drawing on Gutierrez's framework for dimensions of equity, we consider how principals engage in data use in light of the dimensions of access, achievement, identity, and power. Findings suggest each district had its own definition of equity and engaged in work at advancing equity based on this unique definition. We conclude with implications for policy, preparation, and practice related to these different understandings of equity.
Technological Advocacy and Crime Reporting in an HBCU Setting: Addressing the Prospect of Legal Cynicism in the Ebony Tower
Authors: Webb Patrick , Chin Jason , Williams Cynthia-Lee , Dennis Kimya
Published: November 2021

In comparison to white students, the study of Black student attitudes toward crime reporting on college campuses is deficient, especially in historically Black colleges and universities (HBCUs). Using approximately 100 completed student questionnaires, statistical results suggest that the majority of students express a willingness to report a campus-related crime to campus police. The highest reported explanation for refusing to report a crime is based upon the prospect of being labeled in a negative manner. The highest reported explanation for reporting a crime is based upon the receipt of a financial reward and anonymity. Bivariate calculations indicate that age, gender, and residential status are significantly associated with crime reporting decisions. Policy implications, areas of further research, and limitations are provided.
A Two-Wave Study On The Associations Of Burnout With Depression And Anxiety: The Mediating And Moderating Role Of Perceived Family Support
Authors: Koutsimani Panagiota , Montgomery Anthony
Published: November 2021

Studies have shown strong associations between burnout and depression and burnout and anxiety but their exact interrelationships still remain unclear. Few studies have examined the psychosocial mechanisms that might underlie these two relationships. Non-work social factors such as perceived family support can affect mental health. The present study investigated the distinctiveness and the reciprocal associations between burnout and depression, and burnout and anxiety by collecting data twice over an 8 month interval. Perceived family support was examined as a mediating and a moderating factor underlying the two relationships. The Maslach Burnout Inventory-General Survey, the Hospital Depression and Anxiety Scale, and the Julkunen Family Support Scale were administered to employees of the general working population ( N = 52). First, our results revealed moderate associations between burnout and depression, and burnout and anxiety, supporting the distinctiveness of burnout from the two psychological phenomena. Second, the exhaustion and cynicism burnout dimensions showed reciprocal associations with depression. Moreover, anxiety was found to be a consequence of cynicism while it presented reciprocal associations with the exhaustion dimension of burnout. Perceived family support did not mediate the burnout-depression and burnout-anxiety relationships. However, it moderated the depression-exhaustion relationship in a direction opposite from our hypothesis.
Chemotherapy in combination with pembrolizumab and antiangiogenesis in young patients with advanced primary pulmonary mucinous adenocarcinoma: Two case reports
Authors: Zhou Daibing , Gulinuer Wumaier , Zhu Ning
Published: November 2021

Primary pulmonary mucinous adenocarcinoma is an unusual histological type of non-small cell lung cancer and has a rare prevalence at a young age. There is no standard first-line therapy for advanced primary pulmonary mucinous adenocarcinoma in children and young adults—this study reports two rare cases of primary pulmonary mucinous adenocarcinoma with wild-type anaplastic lymphoma kinase and epidermal growth factor receptor ( EGFR) genes. One is a 13-year-old boy ( Case#1 ), and another is a 27-year-old male ( Case#2). Both two cases were treated with antibiotics for suspected pulmonary infection. In our hospital, they were diagnosed with advanced primary pulmonary mucinous adenocarcinoma, the Eastern Cooperative Oncology Group (ECGO) performance status was three scores. We chose pembrolizumab and chemotherapy plus angiogenesis inhibitors for Case#1 and Case#2. The two patients' symptoms improved and presented with a partial response according to the Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria，the scores of ECOG performance status were two for Case#1 and one for Case#2. This study illustrates a promising outcome for advanced primary pulmonary mucinous adenocarcinoma with immunotherapy and chemotherapy plus angiogenesis inhibitors at a young age.
Articulations of workplace precarity: Challenging the politics of segmentation in warehouse logistics
Authors: Barnes Tom , Ali Jasmine
Published: November 2021

As critical nodes for global commodity flows, warehouses are an important example of segmented labour regimes which partition workers into groups with different conditions of security or its opposite, precarity. An emerging literature on warehouse work has tended to place segmentation in the context of managerial despotism based upon low wages, high labour turnover and job insecurity. However, the literature has, thus far, tended to pay comparatively less attention to workers’ collective resistance and its relationship to intra-labour divisions reproduced through segmentation. In refocusing attention to this problem, this article addresses the theoretical status of intra-labour groups, the nature of horizontal worker-to-worker relations, and their interaction with workers’ social identities and vertical capital–labour relations. It argues that the Gramscian concept of articulation provides the most promising frame for understanding these networked relations and for addressing how the politics of segmentation can be challenged by building common cause among divided workers.
Asymmetrical understandings of the value of time between Taiwanese Working Holiday Makers and the Australian government: Cultural exchange or serving time?
Authors: Li Yao-Tai
Published: November 2021

The impact temporary visa status has on the lives of migrants and their experience of time has been widely discussed. Fewer studies, however, focus discussion on the competing interpretations of the value of Working Holiday Makers’ (WHMs) time and the complexities of disruption and (un)certainties: more specifically the contrast between the value the Australian government places on time spent doing agricultural work in rural areas to become eligible for a second visa, and how this time is perceived by WHMs. This article seeks to fill this gap by comparing data drawn from the government’s rhetoric and interviews with Taiwanese WHMs who had worked in regional areas of Australia for three months. I argue that the government selectively highlights to prospective WHMs the value of cultural exchange and tourism (life-value) while downplaying the labor value (money-value) to WHMs’ time. Furthermore, the government and WHMs are not always talking about the same ‘time units’ (working time and holiday time) when applying these values. This article demonstrates that WHMs are conscious of how their time is spent and perceive the three months of specified work as being ‘suspended’, ‘immobile’, and ‘disrupted’, which undermines their life-values and migration flow in Australia.
It's Just the Wilson Way: Investigating the Extended Impact of an Elementary Full-Service Community School Initiative on Middle School STEM-Related Outcomes
Authors: Provinzano Kathleen , Koskey Kristin L.K. , Sondergeld Toni , Flowers Alonzo
Published: November 2021

This study investigated the sustained impact from elementary fullservice community school programming on middle school STEM academic outcomes that could lead to greater college and career readiness, as well as increased STEM career options for underserved urban students. Quantitative findings suggest middle school youth who attended an elementary full-service community school performed better on middle school STEM outcomes and were predicted to be more prepared to graduate and enter a STEM-related field than a matched comparison of peers who did not. Qualitative results explain differences. Two meta-inferences, informal facilitation of STEM and sustained fullservice community school impact, frame the discussion.
De-colonising the right to housing, one new city at a time: Seeing housing development from Palestine/Israel
Authors: Haas Oded
Published: November 2021

The right to housing is generally understood as a local struggle against the global commodification of housing. While useful for recognising overarching urbanisation processes, such understanding risks washing over the distinctive politics that produce the housing crisis and its ostensible solutions in different contexts around the globe. Situated in a settler-colonial context, this paper bridges recent comparative urban studies with Indigenous narratives of urbanisation, to re-think housing crisis solutions from the point of view of the colonised. Based on in-depth interviews with Palestinian citizens of Israel, the paper compares two cases of state-initiated, privatised housing developments, one in Israel and one in the Occupied Palestinian Territories: the new cities Tantour and Rawabi. Each case is examined as a singularity, distinctive formations of the spatialities of Zionist settlement in Palestine, which are now being transformed through privatised housing development. The paper presents these developments as mutually constituted through a colonial-settler project and Palestinian sumud resistance, the praxis of remaining on the land. The paper utilises comparison as a strategy, exploring each new city in turn, to reveal the range of directions in sumud. Thus, by seeing housing development as site for negotiating de-colonisation on the ground, the paper contributes to recent debates over the power of comparative urbanism to re-think global phenomena through treating urban terrains as singularities.
Predicting Heart Rate Variability Parameters in Healthy Korean Adults: A Preliminary Study
Authors: Kim Sung-Woo , Park Hun-Young , Jung Won-Sang , Lim Kiwon
Published: November 2021

The purpose of the study was to examine the development of a multiple linear regression model to estimate heart rate variability (HRV) parameters using easy-to-measure independent variables in preliminary experiments. HRV parameters (time domain: SDNN, RMSSD, NN50, pNN50; frequency domain: TP, VLF, LF, HF) and the independent variables (e.g., sex, age, body height, body weight, BMI, HR, HRmax, HRR) were measured in 75 healthy adults (male n = 27, female n = 48) for estimating HRV. The HRV estimation multiple linear regression model was developed using the backward elimination technique. The regression model’s coefficient of determination for the time domain variables was significantly high (SDNN = R2: 72.2%, adjusted R2: 69.8%, P < .001; RMSSD = R2: 93.1%, adjusted R2: 92.1%, P < .001; NN50 = R2: 78.0%, adjusted R2: 74.9%, P < .001; pNN50 = R2: 89.1%, adjusted R2: 87.4%, P < .001). The coefficient of determination of the regression model for the frequency domain variable was moderate (TP = R2: 75.6%, adjusted R2: 72.6%, P < .001; VLF = R2: 41.6%, adjusted R2: 40.3%, P < .001; LF = R2: 54.6%, adjusted R2: 49.2%, P < .001; HF = R2: 67.5%, adjusted R2: 63.4%, P < .001). The coefficient of determination of time domain variables in the developed multiple regression models was shown to be very high (adjusted R2: 69.8%–92.1%, P < .001), but the coefficient of determination of frequency domain variables was moderate (adjusted R2: 40.3%–72.6%, P < .001). In addition to the equipment used for measuring HRV in clinical trials, this study confirmed that simple physiological variables could predict HRV.
Parameatal urethral cyst in a 9-year-old boy
Authors: Maddileti Varunkumar , Gazula Suhasini , Dantala Praveena , Noonavath Ravinder Naik , Gopikonda Leelarani
Published: November 2021

Parameatal urethral cyst (PUC) is a comparatively unusual pathology in children. Since its first report, approximately 100 cases have been reported in the literature, mostly in the Japanese population. We report such a case in a 9-year old boy who presented with urine stream distortion, successfully managed by complete excision of the cyst, with total removal of the epithelium, which is the treatment of choice to prevent recurrence.