bluuebunny/crossref_metadata_2025 huggingface dataset:
An analysis of different modalities of bone mineral densitometry evaluation in cage subsidence in anterior cervical discectomy and fusion
Authors: Yu Qingsong , Chen Jiabao , Wang Haidong , Ma Lei
Published: December 2024

Objective

To compare the effectiveness of different measurement methods on bone miner density (BMD), including cervical HU of CT, MRI-based cervical vertebral bone quality (C-VBQ), and T value of DEXA, for predicting cage subsidence after single-level ACDF.

Methods

This is a retrospective study, and patients who underwent single-level ACDF from June 2019 to June 2022 were recruited. We collected preoperative total segmental vertebral height (pre-TSVH), cage subsidence height, cervical angle (CA), T1-slope, straight or reverse cervical curvature, mean HU value of C3–7 (C-HU), mean HU of segment (seg-HU), C-VBQ, segmental C-VBQ (seg-VBQ), and total lumbar T value (T value). The variables between the two groups were compared by Student's t test or chi-square test. Logistic regression was used to determine the independent risk factors for subsidence. The ROC curve was used to analyze the predictive efficiency of C-HU, seg-HU, C-VBQ, seg-VBQ and T value for cage subsidence. Finally, the correlations of C-HU, seg-HU, C-VBQ, seg-VBQ, T value and subsidence height were analyzed.

Results

A total of 320 patients were included in this study, and 97 patients (30.31%) had cage subsidence at the last follow-up. The subsidence height was 4.25 ± 0.937 mm in the subsidence group and 1.40 ± 0.726 mm in the nonsubsidence group. There were statistically significant differences between the two groups in bone mineral density-related indexes, including C-HU, seg-HU, C-VBQ, seg-VBQ, and T value (p < 0.05). Logistic regression analysis showed that C-HU was an independent risk factor for vertebral subsidence after single-level ACDF. ROC curve analysis showed that C-HU had the largest AUC of 0.897 (0.862, 0.933) in predicting vertebral subsidence. Correlation analysis showed that C-HU had a high correlation with the T value (r = 0.662, p < 0.001), while C-VBQ had a low correlation with the T value (r = −0.173, p = 0.002), and C-VBQ had a low correlation with subsidence height (r = 0.135, p = 0.016).

Conclusion

Our study showed that compared with the C-VBQ and T value, C-HU is more effective for predicting cage subsidence after ACDF. Using the segmental index of C-VBQ or HU could not improve predictive effectiveness. C-VBQ may be insufficient in predicting cage subsidence and estimating BMD.
Golden era of radiosensitizers
Authors: Cizkova Jana , Dolezal Ondrej Jan , Buchta Vojtech , Pospichal Jan , Blanar Vit , Sinkorova Zuzana , Carrillo Anna
Published: December 2024

The past 30 years have brought undeniable progress in medicine, biology, physics, and research. Knowledge of the nature of the human body, diseases, and disorders has been constantly improving, and the same is true regarding their treatment and diagnosis. One of the greatest advances in recent years has been the introduction of nanoparticles (NPs) into medicine. NPs refer to a material at a nanometer scale (0.1–100 nm) with features (specific physical, chemical, and biological properties) that are broadly and increasingly used in the medical field. Their applications in cancer treatment and radiotherapy seem particularly attractive. In this field, inorganic/metal NPs with high atomic number Z have been employed mainly due to their ability to enhance ionizing radiation’s photoelectric and Compton effects and thereby increase conventional radiation therapy’s efficacy. The improvement NPs enable relates to their enhanced permeation ability and longer retention effect in tumor cells, capacity to reduce toxicity of commercially available cancer drugs through advanced NPs drug delivery systems, radiation sensitizers of tumors, or enhancers of radiation doses to tumors. Advanced options according to size, core, and surface modification allow even such multimodal approaches in therapy as nanotheranostics or combined treatments. The current state of knowledge emphasizes the role of gold nanoparticles (AuNPs) in sensitizing tumors to radiation. We have reviewed AuNPs and their radiosensitizing power during radiation treatment. Our results are divided into groups based on AuNPs’ surface modification and/or core structure design. This study provides a complete summary of the in vivo sensitizing effect of AuNPs, surface-modified AuNPs, and AuNPs combined with different elements, providing evidence for further successful veterinarian and clinical implementation.
Influence of maternal nutrition and one-carbon metabolites supplementation on bovine antimicrobial peptides in fetal and maternal tissues
Authors: Daneshi Mojtaba , Borowicz Pawel P. , Hirchert Mara R. , Entzie Yssi L. , Syring Jessica G. , King Layla E. , Safain Kazi Sarjana , Anas Muhammad , Reynolds Lawrence P. , Ward Alison K. , Dahlen Carl R. , Crouse Matthew S. , Caton Joel S.
Published: December 2024

Introduction

Maternal nutrition during pregnancy critically influences offspring development and immune function. One-carbon metabolites (OCM) are epigenetic modifiers that may modulate antimicrobial peptide (AMP) expression, which is vital for innate immunity. This study investigated the effects of maternal nutrient restriction and OCM supplementation on mRNA expression of AMP in fetal and maternal lung, mammary gland, and small intestine of beef cattle.

Methods

Twenty-nine crossbred Angus beef heifers were synchronized for estrus and artificially inseminated. They were assigned to one of four treatments in a 2 × 2 factorial design: nutritional plane [control (CON) vs. restricted (RES)] and OCM supplementation [without OCM (−OCM) or with OCM (+OCM)]. Heifers on the CON diet were fed to gain 0.45 kg/day, while RES heifers were fed to lose 0.23 kg/day. Treatments were applied from day 0 to 63 of gestation, after which all heifers were fed a common diet to gain 0.45 kg/day until day 161 of gestation, when samples were collected. Quantitative RT-qPCR was used to assess mRNA expression of AMP.

Results

Nutritional plane had no effect (p ≥ 0.24) on mRNA expression of AMP in either the fetus or dams. However, the mRNA expression of cathelicidin5 (CATHL5; p = 0.07) and bovine neutrophil β-defensin5 (BNBD5; p = 0.07) in the fetal lung and mammary gland, respectively, was lower in the +OCM groups compared to the −OCM groups. In the maternal small intestine, the expression of enteric β-defensin (EBD) was lower (p = 0.01) in the +OCM groups compared to the −OCM groups. Additionally, in the maternal lung, there was a tendency (p = 0.06) for an interaction in CATHL5 mRNA expression, with the RES + OCM group showing greater expression compared to the CON + OCM (p = 0.07) and RES − OCM (p = 0.08) groups.

Discussion

Our findings suggest that while restricted maternal nutrition did not affect mRNA expression of AMP, OCM supplementation modulated AMP expression in both fetal and maternal tissues. Further research is needed to elucidate the mechanisms underlying OCM’s impact on AMP expression.
Od nazwy żeńskiej do feminatywum. Z dziejów kategorii słowotwórczej i jej nazewnictwa
Authors: Woźniak Ewa
Published: December 2024

The article presents the history of the use of the term feminativum in Polish linguistic literature and in the general language. Moreover, it discusses the issue of isolating the word-formation category of feminine names in old grammars, as well as its contemporary definitions. The study used manual and automated (corpus-assisted) data extraction. The author posits that it was Piotr Statorius-Stojeński who distinguished the category of female names in his grammar of the Polish language for foreigners published in Latin in 1568. The author also determined that the term feminativum was propagated by Bogusław Kreja, who was the first to use it in his 1964 article. Although the term appeared only occasionally in linguistic publications in the second half of the 20th century, it came to be used regularly as a synonym for the term feminine names at the turn of the 2010s and 2020s. However, the inclusion of feminativum on the list of words in the Polish Word of the Year 2019 competition may have contributed to its popularity across the media.
A Metabolomic Analysis of Tomato Fruits in Response to Salt Stress
Authors: Sun Yeshuo , Ma Ruiping , Yang Xiaoqing , Zhang Guoxin
Published: December 2024

Salt stress affects all stages of tomato growth and development, reducing tomato yield, but moderate salt stress improves tomato quality. To gain a deeper understanding of the effect of salt stress on tomato fruits, a widely targeted metabolomic method based on ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) was used to analyze tomato fruits under three different soil salt contents (CK: 0.05 g·kg−1; MS: 3 g·kg−1; and HS: 6 g·kg−1). A total of 847 metabolites were detected in tomato fruit under salt stress, including six primary metabolites such as lipids, amino acids and their derivatives, sugars, nucleotides and their derivatives, and organic acids, and nine secondary metabolites such as phenolic acids, alkaloids, and flavonoids. There were 54 different metabolites in the three treatments, mainly flavonols and phenolamines. Dopamine, galactotol, and mannitol were not detected in the control group, but their contents were higher in the salt treatment. KEGG analysis showed that the differential metabolites were mainly concentrated in flavonoid biosynthesis, betaine metabolism, sulfur metabolism, and galactose metabolism. This study provides a theoretical basis for the regulation of tomato quality through salt stress.
Research on the need for social rehabilitation of people with neurological diseases in a hospital
Authors:   ANO «Central Clinical Medical and Sanitary Unit», Magnitogorsk, Maksakova N. V. , Slepukhina G. V. ,   Department of Social Work and Psychological and Pedagogical Education of the Federal State Budgetary Educational Institution of Higher Education  «Magnitogorsk State Technical University named after G. I. Nosov»
Published: December 2024

The article presents a study of the need for social rehabilitation of persons
with neurological diseases in hospital. People with neurological diseases often need
social rehabilitation to minimize the consequences of the disease. The study examined
the opinion of patients of the inpatient neurological department of the ANO «TsKMSCh»
about the organization of social rehabilitation.
Land plot as a kind of monetary capital. Land market and cadastral value of agricultural land
Authors:   Federal State Budgetary Scientific Institution «Federal Research Center of Agrarian Economy and Social Development of Rural Areas - All-Russian Research Institute of Agricultural Economics», Moscow, Alakoz V.V., , Gorin A.D. ,   Federal State Budgetary Scientific Institution «Federal Research Center of Agrarian Economy and Social Development of Rural Areas - All-Russian Research Institute of Agricultural Economics», Moscow, Nosov S.I. ,   Plekhanov Russian University of Economics
Published: December 2024

The basis for determining payments for the use of agricultural land plot is land rent –
the excess value of agricultural products over the average profit. Rent is a "surplus", the taxation
of which does not affect the incentives for production. The rent tax does not lead to distortions
in the economy and does not reduce its efficiency, unlike destructive taxes on productive capital
and labor - a tax system that punishes achieving high results in hard work and entrepreneurship.
The amount of tax rate established by the Tax Code of the Russian Federation for land plots
classified as agricultural lands for agricultural production - 0.3% of the cadastral value of a land
plot - leads to speculative enrichment through the purchase of state land with the subsequent
leasing at a rental price ten times higher than the average nominal land fee and the refusal
of regional and municipal authorities to provide state and municipal lands for ownership to
citizens and legal entities, as authorities prefer to lease these lands. This is how land has become
a source of unearned wealth. Social, economic and environmental consequences of this clearly
affect the welfare of society.
The article presents a simple model for the annual calculation of land rent based on data from
commodity producers of the agro-industrial complex on production, expenses, cost price, and
profitability of crop products.
Recognition of open soil surface as a method of restoring agricultural land use maps in the Republic of Sakha (Yakutia)
Authors:   FSBSI Federal Research Center, Rukhovich D. I. ,   V.V. Dokuchaev Soil Institute,   , Moscow, Shapovalov D. A. ,   FSBSI Federal Research Center "V.V. Dokuchaev Soil Institute;, Moscow, Chernousenko G. I., ,   FSBSI Federal Research Center "V.V. Dokuchaev Soil Institute;, Moscow, Koroleva P. V., ,   FSBSI Federal Research Center; V.V. Dokuchaev Soil Institute;, Moscow, Rukhovich A. D. ,   State University of Land Use Planning, Moscow
Published: December 2024

In this paper the authors analyzed data from five different sources – topographic
maps, land management materials, UAV survey, retrospective monitoring of soil and land
cover, and recognition of open soil surface - to identify and involve abandoned arable land into
agricultural circulation. The result of “on-ground” verification showed the different accuracy of
the methods. Retrospective monitoring of soil and land cover provides the highest correctness,
close to 100%. The combination of this technology with recognition of open soil surface, which
allows cutting off unsuitable lands, can provide a solution for inventory arable land and
introducing it into agricultural circulation.
Beyond Unconditional Surrender: Romania’s Diplomatic Campaign for a Conditional Armistice (1942–1944)
Authors:   Department for International Studies and Contemporary History, Babeş-Bolyai University, ClujNapoca, Alexandrescu Mihai
Published: December 2024

Romania’s exit from World War II on 23 August 1944 came after more than two years of complex diplomatic negotiations for an unconditional armistice. This article examines Romania’s diplomatic efforts undertaken between 1942 and 1944, highlighting the challenging conditions imposed by the Allies and the internal political dynamics. Romanian leaders like Mihai Antonescu and Iuliu Maniu endeavored to secure favorable terms to safeguard national interests despite significant hurdles. Their efforts, influenced by the strategic interests of the Allied powers and the changing military landscape, ultimately led to Romania’s shift from the Axis to the Allied side, with profound postwar consequences.
Jesuit Education in Cluj (1579–1785): A Historical and Historiographical Overview
Authors:   Center for Transylvanian Studies, Romanian Academy, Páll-Szabó Ferenc Daniel , Kósa Alexandru ,   Titu Maiorescu Institute for Banatian Studies, Romanian Academy
Published: December 2024

The objective of this article is to present the history and historiography of the educational establishment operating under the patronage of the Jesuit Order in Cluj (Klausenburg, Kolozsvár), known during time as the Jesuit Major College, the Claudiopolitan Academy, and the Academic College with the rank of University in Cluj.
VALIDITY OF SPARKOL VIDEOSCRIBE BASED ANIMATED VIDEO FOR HANDLING UNDERNUTRITION IN TODDLERS
Authors: Harefa Wiwien Ellora Ester Riang , Mulyani Sri , Andayani Tri Rejeki
Published: December 2024

Gizi kurang merupakan suatu kondisi balita tidak mencapai berat badan ideal, yang bisa memengaruhi pertumbuhan tinggi badan, Berbagai upaya dapat dilakukan untuk menangani antara lain dengan memberikan edukasi gizi melalui media video animasi. Penelitian ini bertujuan untuk mengembangkan materi edukasi berupa video animasi berbasis Sparkol Videoscribe untuk membantu menangani masalah gizi kurang pada balita. Penelitian ini menggunakan metode Reasearch and Development yang mengacu pada kerangka kerja ADDIE meliputi (Analyze, Design, Development, Implementation, dan Evaluation). Validasi video animasi berbasis Sparkol videoscribe melibatkan 3 ahli yaitu  ahli materi, ahli bahasa, dan ahli media. Selanjutnya dilakukan uji coba (sampel terbatas n = 10) pada ibu balita gizi kurang. Pemilihan sampel menggunakan teknik purposive sampling. Metode rancangan quasi expeimental dengan desain nonequivalent control group dan dampak penggunaan video diukur dengan tiga alat ukur, yaitu: kuesioner pengetahuan gizi (reliabilitasnya 0,71), kuesioner efikasi diri (reliabilitasnya=0,95), kuesioner pola asuh makan (reliabilitasnya=0,95). Hasil penelitian menunjukkan media video animasi berbasis Sparkol Videoscribe untuk menangani masalah balita gizi kurang dinilai layak dengan skor rata–rata dari ahli materi 84%, ahli bahasa 86,6% dan ahli media 86%, hasil uji coba video animasi dengan small group dihasilkan 85,5% dengan kategori sangat layak dan hasil uji coba kuesioner menunjukkan ada peningkatan pengetahuan gizi, efikasi diri dan pola asuh makan dengan kategori sedang. Kesimpulannya media video animasi berbasis Sparkol Videoscribe yang dikembangkan dalam penelitian dapat diterapkan untuk membantu menangani masalah gizi kurang pada balita.
Ultrassonografia point-of-care no diagnóstico rápido de obstruções gastrointestinais em pequenos animais
Authors: Soares Gabrielle Vieira , Medeiros Fernanda Peres , Junior Raul Martins
Published: December 2024

A ultrassonografia point-of-care (POCUS) vem emergindo como uma ferramenta valiosa na prática veterinária, especialmente para o diagnóstico rápido de obstruções gastrointestinais em pequenos animais, condições essas que demandam intervenções rápidas para que se tenha um melhor prognóstico. POCUS oferece uma abordagem não invasiva e acessível para avaliar o trato gastrointestinal em tempo real. Avanços tecnológicos, como a melhoria na resolução dos equipamentos e o desenvolvimento de sondas específicas, têm aprimorado sua eficácia. Técnicas avançadas, como a elastografia, também contribuem para o diagnóstico diferencial, avaliando a elasticidade dos tecidos. Esta revisão de literatura examina a eficácia e inovações recentes na aplicação de POCUS para obstruções gastrointestinais em pequenos animais, comparando-a com outras modalidades de imagem, como radiografia e ultrassonografia convencional, além de discutir protocolos específicos para avaliação e tratamento dessas condições. A análise visa fornecer uma visão abrangente das tendências atuais, destacando o potencial de POCUS como recurso diagnóstico essencial na prática veterinária contemporânea.
العوامل المؤثرة في بروز مشكلات مهنة المحاسبة: دراسة ميدانية مطبقة على الشركات الصناعية المساهمة العامة الأردنية
Authors: صيام وليد زكريا
Published: December 2024

هدفت الدراسة إلى تقييم مشكلات مهنة المحاسبة في الشركات الصناعية المساهمة العامة الأردنية، والتعرف إلى العوامل المؤثرة في بروزها، إضافة إلى تحديد الأهمية النسبية لكل مشكلة، وتصنيفها إلى مشكلات خاضعة لسيطرة الشركة أو إلى مشكلات ذات صبغة عامة، إضافة إلى اقتراح الحلول المناسبة. وقد خلصت الدراسة إلى أن هناك عدة عوامل تؤثر في بروز مشكلات مهنة المحاسبة، كما أوصت باقتراحات وتوصيات متعددة من شأنها معالجة هذه المشكلات.
Rukavice za korisnike invalidskih kolica
Authors: Bogović Slavica
Published: December 2024

Za interakcĳu s okolinom koriste se ruke, pri tome ih je važno zaštiti ih od vanjskih utjecaja. Rukavice su prva barĳera između ruku i okoline koje služe za zaštitu ili pomoć pri obavljanju aktivnosti. Osobe s invaliditetom ruke često koriste za komunikacĳu ili kretanje ovisno o vrsti i stupnju invaliditeta. Korisnici invalidskih kolica se svakodnevno susreću s mnogobrojnim preprekama, a savladavanje prepreka je ovisno o invaliditetu i okruženju. Mnogobrojne barĳere, poput rubnjaka, stepenica, uskih prolaza i sl. zahtĳevaju dodatne napore pri kretanju. U ovom radu su prikazana istraživanja vezana za oblik i korištenje rukavica korisnika ručno pokretanih invalidskih kolica i motornih invalidskih kolica. Izdvojena su istraživanja rukavica kao individualizirane zaštitne opreme i upravljačke opreme invalidskih kolica.
ВОЗМОЖНОСТИ ЭЛЕКТРОМЕТРИЧЕСКОГО МОНИТОРИНГА ДЛЯ ОПРЕДЕЛЕНИЯ ОРЕОЛОВ РАСПРОСТРАНЕНИЯ ИЗБЫТОЧНЫХ РАССОЛОВ В ПРЕДЕЛАХ ПОЛИГОНОВ ЗАКАЧКИ
Authors: А.А. Тайницкий , Р.А. Богданов , Ю.И. Степанов , Е.С. Зубрикова , М.С. Лучников
Published: December 2024

В статье представлены результаты мониторинговых электрометрических наблюдений методом вертикального зондирования (ВЭЗ), выполненных одновременно с закачкой избыточных рассолов высокой минерализации в надсолевые породы. Для сокращения количества шламохранилищ и снижения их негативного воздействия на окружающую среду современные компании прорабатывают возможность безопасно размещать и утилизировать избыточные рассолы в подземных горизонтах-коллекторах. Однако важно проводить контроль над распространением рассолов для оценки техногенной нагрузки на подземные воды. Таким образом, электроразведочные мониторинговые наблюдения выполнялись для определения ореола распространения рассолов в зоне активного водообмена и оценки засоления подземных вод до глубины 170 м.

To reduce the number of sludge storage facilities and reduce their negative impact on the environment, modern companies are exploring the possibility of safely placing and disposing of excess brines in underground reservoirs. However, it is important to monitor the spread of brines to assess the anthropogenic load on groundwater. The article presents the results of monitoring electrometric observations using the vertical electrical sounding (VES) method, performed simultaneously with the injection of excess brines of high mineralization into the well. Observations were carried out to determine the halo of brine distribution in the zone of active water exchange and to assess the salinity of groundwater to a depth of 170 meters.
HUMAN RESOURCE MANAGEMENT AS A DIRECTION OF DIAGNOSTICS OF THE HUMAN RESOURCE MANAGEMENT SYSTEM IN MARTIAL
Authors: Vuychenko Maryna
Published: December 2024

The article notes that the extremely difficult conditions in which our country currently finds itself have a negative impact on all spheres of society. The most valuable resource is the human one. The war prompted a significant part of the economically active population to leave abroad, many employees of enterprises were forced to leave their permanent place of work due to the occupation of territories, a large proportion of former qualified workers became defenders of the country. Under such conditions, an extremely important issue is the development of measures to support the activities of both large and small enterprises, because timely paid taxes are the key to the country's stability in war conditions. The article substantiates that in a general sense, human resource management is a complex process that combines economic, social, psychological, demographic and other tools and factors of reproduction, advanced training and influence on the labor behavior of employees in order to increase labor efficiency. This requires management to take a systematic approach to the use of human capital. At the same time, the effectiveness of the use of labor potential is manifested in three areas: practical activity, the employee's orientation to meeting his own needs and orientation to the future of the enterprise. Personnel management is at the center of organizational management.
The article notes that the literature considers four levels of personnel management (human capital): political - personnel policy of the state; strategic - labor resources management; tactical - actual personnel management of the industry and enterprise, operational - direct work with personnel. It is emphasized that personnel management methods are divided into: economic (forecast and planning of personnel work, formation of labor resources and sources of their provision); organizational and administrative (establishment of organizational ties, legal provisions and norms); socio-psychological (specific means of influencing the process of formation and development of the labor collective and individual employees); state and administrative (regulation of the movement of labor resources, labor market at the state and regional levels).
ARTIFICIAL INTELLIGENCE IN LVIV RESTAURANTS: IMPACT ON SERVICE AND CUSTOMER EXPERIENCE
Authors: Fil Mariya , Bezruchko Lubomyr , Bilanyuk Olha , Zhuk Yuriy
Published: December 2024

The introduction of artificial intelligence (AI) into the restaurant business in Lviv faces several significant challenges that require a comprehensive approach to solving them. One of the main challenges is the technical integration of AI into existing restaurant processes. Restaurants must adapt their operating systems to the latest technologies, which require updating software and creating an infrastructure for data processing. The main technological innovations implemented in Lviv restaurants can be divided into several categories: 1. Self-service systems. An example is: McDonald's (selected establishments) - interactive terminals for self-ordering and payment, which significantly speed up the service process and allow you to avoid queues during peak hours. 2. Mobile applications for ordering. Lviv Croissants - a chain of establishments that allows you to order products through the application and pick them up without waiting. Sushi delivery is also known as an application, for example, Osama sushi. In addition to the application, there may also be a website of the establishment, such as Pizza Celentano, Smaki maki, La Piets. 3. Smart queue management systems. Family restaurant "Crazy Town" (Victoria Gardens Shopping Center) - uses a table reservation and queue management system via a mobile application. Table reservations, but via a chat bot, can also be made at the "Hot Bowl" establishment. 4. Automation of food preparation. Salalat - a healthy food establishment where the salad preparation process is automated for faster customer service, including in the take-away format. 6. Order personalization technologies. Premium restaurants in Lviv, such as Park.
However, the study also found that the integration of AI requires competent staff training and proper adaptation of technologies to the specifics of the market and consumers. The human factor remains critically important in ensuring a positive customer experience, so the harmonious combination of AI with traditional service methods is key.
MECHANISMS OF PUBLIC ADMINISTRATION FOR OVERCOMING POVERTY AND IMPROVING THE STANDARD OF LIVING IN UKRAINE
Authors: Kupriychuk Andriy , Kupriychuk Vasyl
Published: December 2024

The methods used by public administration to combat poverty and improve the quality of life for Ukrainians are thoroughly examined in this article. Standard of living is the most significant social category, which is one of the primary features of poverty as a social phenomenon. Its foundations include the consumer basket and the subsistence minimum; property potential as viewed through the lens of resource security; the poverty scale, which takes into account the efficacy of state social policy; and the poverty culture and subculture as markers of the poor's disconnection from societal norms and values. It is shown how crucial elements of public administration formation are to enhancing the channels of communication between the government and the populace.
It would most effectively support the growth of civil society. Furthermore, the theory of public administration views people as active participants in this administration when it comes to reducing poverty and improving the standard of living for the populace. In the practical dimension, it is explained that the tactics, initiatives, and resources employed by state authorities, local self-government entities, and public sector organizations to address the issue of poverty in society serve as public management tools for overcoming poverty.
The goal of these mechanisms is to improve the social and economic circumstances of the most vulnerable segments of society. Thus, they necessitate the collaboration of civil society, local self-government, and the state government. It was observed that the state should not take a disorganized approach to lowering or eliminating poverty. It must be targeted, intentional, and ideally preventive in order to enable the implementation of numerous projects and programs that will most effectively combat poverty. At the same time, the state's focus on creating favorable conditions for socially conscious businesses can and should be a key component of its strategy to combat poverty. The creation of mechanisms for the active interaction of state authorities, local self-government bodies, civil society, socially conscious business, and the scientific community is described as a crucial component of public administration in terms of eradicating poverty and improving the standard of living in post-war Ukrainian society.
Each of them is aimed at restoring the country’s economic potential, infrastructure on the affected territories, the creation of new jobs and effective social security mechanisms for the most vulnerable sections of the population.
UKRAINE'S STATE POLICY ON OCCUPATIONAL HEALTH AND SAFETY
Authors: Hayuk Maksym
Published: December 2024

The article looks at how Ukraine treats workers' health and safety. Occupational health and safety is a system of measures and means that are used by legal entities and people to make sure that working conditions are good enough to prevent threats to an employee's life and health while he is doing his job.
The essence and principles of state policy in the field of occupational safety and health have been explained. These principles include the importance of protecting the life and health of employees, the responsibility of the employer for creating safe and healthy working conditions, the need to keep production, technologies, and products safe and harmless, and the need to help enterprises create safe and harmless working conditions.
 We need to solve occupational safety problems using programs from different parts of the country and around the world. We should also consider other things like science and technology, protecting the environment, protecting workers, and paying people who get hurt at work or get sick at work.
Creating safety rules for all businesses, no matter who owns them or what they do. Making sure workers are safe and healthy by changing how they work, considering their health and mental state. The government can help pay for safety measures, but only if it doesn't go against the rules.
It is said that occupational safety and health have a big impact on modern economic processes. Economic importance is measured by how well workers work, how much money they make from working, and how much they pay for injuries or illnesses that affect their health and safety.
DIAGNOSTICS OF REGIONAL DIFFERENCES IN THE HUMAN RESOURCE MANAGEMENT SYSTEM IN MODERN CONDITIONS
Authors: Vuychenko Maryna
Published: December 2024

The article notes that in the conditions of war in which our country is currently located, an important issue is the development of measures to regulate objective processes in the labor market caused by the departure of a significant number of qualified specialists abroad, the movement of the employed population from region to region, and the mobilization of a significant part of the economically active population. The article indicates that within the framework of this problem, the main task is to improve the interaction between the central government and local government bodies, taking into account the real state of the military, economic, demographic, social, political, and humanitarian situation. It is necessary to significantly expand the powers of territorial communities in all spheres of public life. Management by peaceful methods during war is impossible. This is especially relevant, since the administrative and territorial reform has not yet been completed and is closely related to the results of hostilities. The article notes that the war has imposed new requirements on the style of personnel management. The main thing is to preserve labor capital and increase the efficiency of employees. The management system should be flexible and economically justified and legally impeccable. This approach assumes a certain freedom of decisions and actions of managers. A state of emergency allows for extraordinary organizational measures, in particular in the field of logistics of goods and services. The article notes that the regulatory documents that we have already analyzed emphasize that during martial law, the freedom of decisions and actions for managers of organizations may be limited. The instability of the political and economic situation can lead to a disruption of investment in production and the supply of products and spare parts, as well as electricity, which in turn can increase the risk of injuries, violations of labor discipline, and staff turnover. Preservation of labor potential is a priority for every manager. For this, it is necessary to use various forms and means of stimulating personnel. Management practice has developed such forms of employee encouragement as mutual support and cooperation, material and moral incentives, training and development, advanced training, and prospects for professional and career growth.
THEORETICAL ASPECTS OF THE DEVELOPMENT OF TRANSNATIONAL CORPORATIONS IN THE CONDITIONS OF GLOBAL ECONOMIC TRANSFORMATION
Authors: Mosiichuk Iryna
Published: December 2024

The article explores relevant issues regarding the role of transnational corporations (TNCs) in the processes of globalization and the integration of the world economy. The author analyzes the activities of TNCs as key players on the global economic stage, focusing on their impact on global trade flows, economic dynamics, and the development of countries. TNCs produce goods and services on an international level, make significant investments, and contribute to the spread of advanced technologies, increasing competition and integrating global markets. The article also notes that globalization is an objective circumstance in the development of the modern economy, which is accompanied by the growing interdependence of countries. The role of TNCs in creating international production and providing access to skilled labor resources, as well as their influence on scientific and technological progress, is separately examined. It is determined that TNCs often become a driving force of globalization as they stimulate the development of international trade and investment, spread advanced technologies, and improve productivity across various markets. The main classifications of TNCs are analyzed according to industry, geographic, size, and market criteria, helping to better understand their structures and strategic orientations. In addition, the main directions of TNC activities, such as production, trade, and investment, are studied, making them the primary drivers of economic globalism. The article draws attention to the interaction of TNCs with local markets and their impact on local economies, particularly through investment projects, job creation, and infrastructure development. It is emphasized that TNCs are important factors in economic growth and improving resource efficiency in various regions of the world. Special attention is paid to how the activities of TNCs contribute to the dissemination of advanced management practices and technologies, which allows for increased labor productivity and the development of human capital in host countries. The article also considers the challenges related to the activities of TNCs, such as mergers and acquisitions, which can lead to market monopolization and unequal distribution of the benefits of globalization. The influence of TNCs on international relations and the regulation of economic activity is examined, requiring national governments to develop effective strategies to attract foreign investment and minimize potential risks. Overall, the article highlights the essence of TNCs as important participants in the process of economic globalization, emphasizing their ability to adapt to global challenges while also shaping new directions for the development of the world economy.
METHODOLOGICAL PRINCIPLES OF PUBLIC POLICY DEVELOPMENT ON HEALTHCARE STAFFING
Authors: Makarchuk Vadym
Published: December 2024

The article provides a comprehensive analysis of the methodological principles of public policy development regarding human resources in the healthcare sector. It is noted that the majority of scientific works by domestic scientists are devoted to the study of public policy issues and management in the healthcare sector. All of them consider approaches to human resources policy and the competencies formation of healthcare managers.
It is proven that the result of the reform should be the creation of a national model of healthcare. It’s the activities and infrastructure will meet public needs and take into account the geographical, historical and cultural features of Ukraine. When developing and implementing reforms, it is necessary to take into account many regional features. Among them are the structure of morbidity, the material condition of medical and preventive institutions, the presence and characteristics of sports, medical and recreational facilities. We can’t forget the importance of population density, the state of the transport and logistics sector, climatic and natural conditions, and the ecological situation in the region.
It is noted that today in the healthcare system of Ukraine, data is not calculated. The justified need for managerial personnel is not determined as well. So there is no Methodology for calculating the needs for managerial personnel in the healthcare system. Accordingly, it is not possible to ensure an effective state order for the training of managerial personnel. A particularly important direction of the state personnel policy in the healthcare sector should be the training and maintenance of a high professional level of managerial personnel. We must consider the formation of an effective personnel reserve, as well as the use of the method of current personnel rotation at the central and regional levels.
To achieve the best results in reforming the national healthcare sector, the personnel policy should be prioritized not formally, but reasonably developed taking into account the real needs of the industry. The proper level of medical services depends on two criteria. The first one is the quality of medical personnel training at different stages. And the second one is the training of managers for the medical industry.
Autocritique de l’énonciation : Fragments d’un discours amoureux et ses limites
Authors: Silva Silvana , Badir Sémir
Published: December 2024

Fragments d’un discours amoureux présente un dispositif textuel et énonciatif qui est resté jusqu’ici inaperçu. L’hypothèse conduisant le présent essai est que ce dispositif, très particulier, permet une sorte d’autocritique, que Roland Barthes appelle lui-même « autocritique de l’énonciation » : le sujet amoureux s’y exprime en opérant un retour critique sur son discours. Pour confirmer cette hypothèse, nous montrons d’abord ce qu’un tel dispositif doit au projet de sémiologie littéraire conçu et mis en oeuvre par Barthes dans son enseignement et son travail d’écriture. Par la suite, nous mettons en avant la matérialité discursive de ce dispositif, en analysant divers effets sémantiques produits par les noms inscrits dans les marges du livre, en particulier le nom du psychanalyste Donald Winnicott.
La enunciación como "un fenómeno de estimación subjetiva"
Authors: Tatit Luiz
Published: December 2024

Este artículo examina los efectos de la enunciación sobre los modos de existencia semiótica poniendo de relieve las apreciaciones de contenido elaboradas por los sujetos (enunciativo y enuncivo) y los acentos que hacen que cada modo resulte más o menos impactante, dependiendo de la implicación afectiva de los actores involucrados. Este coeficiente de intensidad afecta los cuatro modos (realización, potencialización, virtualización y actualización) y termina por definir, a nuestro juicio, el cálculo enunciativo presente en todo discurso, y que Greimas llamó “estimación” al inicio de la década de 1970. El artículo combina la estimación (apreciativa) con la acentuación (afectiva) promovida por la semiótica actual, que tiene como recurso analítico los incrementos más y menos, así como sus sugerentes combinaciones, nociones todas propuestas por el modelo semiótico de Claude Zilberberg. Precisamente porque produce en el mismo acto enunciativo los cuatro modos de existencia, la enunciación genera entre ellos una enorme movilidad de los vínculos actanciales vividos en la realización, pues dispone del recuerdo y de la esperanza como dispositivos que mantienen esos contenidos —especialmente los acentuados— en continua circulación.
Pengembangan Media Pembelajaran Komik Digital Berbasis Book Creator dalam Model Discovery Learning pada Materi Kesetimbangan Kimia Kelas XI MIPA SMA Kartika XX-1 Makassar
Authors: Salsabila Rezky Kaswa , Anwar Muhammad , Hardin Hardin
Published: December 2024

ABSTRAK
Penelitian ini merupakan penelitian pengembangan yang bertujuan untuk mendeskripsikan tahapan pengembangan komik digital dalam model discovery learning dengan menggunakan model pengembangan ADDIE dan menghasilkan produk berupa komik digital pada materi pokok kesetimbangan kimia yang valid, praktis, dan efektif. Pengembangan ini mengacu pada model pengembangan ADDIE yang meliputi lima tahap pengembangan yaitu tahap analisis, tahap perancangan, tahap pengembangan, tahap implementasi, dan tahap evaluasi. Hasil penelitian ini adalah: (1) kevalidan dari ahli media dan materi, masing-masing sebesar 3,42 dan 3,6 yang termasuk dalam kategori sangat valid, (2) kepraktisan dari lembar observasi keterlaksanaan pembelajaran, angket respon guru dan peserta didik berturut-turut sebesar 98,66%, 91%, dan 93% yang termasuk dalam kategori sangat praktis, (3) keefektifan dari angket minat belajar mencapai 89% dan ketuntasan kelas sebesar 88% sehingga termasuk dalam kategori efektif. Berdasarkan data tersebut, disimpulkan bahwa komik digital berbasis Book Creator yang dikembangkan dengan model ADDIE dinyatakan valid, praktis, dan efektif digunakan dalam pembelajaran.

ABSTRACT
This research is a research and development that aims to describe the stages of digital comic in the discovery learning model using the ADDIE development and produce a digital comic on the subject matters of chemical equilibrium that are valid, practical, and effective. This development refers to the ADDIE model which includes analysis, design, development, implementation, and evaluation. The results of this research are: (1) the validity of the media and material expert, respectively 3,42 and 3,6 which is included in the very valid category, (2) the practically of the learning implementation observation sheet, the teacher and student response questionnaires successively equal to 98,66%, 91%, and 93% which are included in the very practical category, (3) the effectiveness of the learning interest questionnaires which reached 89% and learning outcomes test that achieves class completeness is 88% that it is included in the effective category. Based on these data, it was concluded that the digital comic based on Book Creator developed with the ADDIE model was stated to be valid, practical, and effective for use in learning.
Identifikasi Senyawa Patkouli Alkohol dari Minyak Atsiri Daun Nilam (Pogostemon cablin benth.) Identification Of Patchouli Alcohol Compounds from The Essential Oil Of Patchouli Leaves (Pogostemon cablin benth.)
Authors: Selvianti Selvianti , Wijaya Mohammad , Maryono Maryono
Published: December 2024

Penelitian ini bertujuan untuk mengetahui banyaknya kandungan senyawa patkouli alkohol yang terdapat dalam minyak atsiri daun nilam dan karakteristik senyawa patkouli alkohol yang terdapat dalam minyak atsiri daun nilam. Sampel penelitian diambil dari Desa Paruttellang, Kecamatan Ngapa, Kabupaten Kolaka Utara, Provinsi Sulawesi Tenggara. Tahap penelitian ini terdiri dari preparasi sampel, destilasi air, fraksinasi, analisis GC-MS, pemurnian dan identifikasi. Hasil penelitian berupa minyak atsiri daun nilam sebanyak 57 mL yang berwarna kuning muda dan memiliki wangi yang khas. Analisis menggunakan GC-MS terhadap fraksi B, fraksi C, fraksi D dan fraksi E menghasilkan kandungan senyawa patkouli alkohol berturut-turut sebanyak 22,71%; 30,13%; 33,09% dan 22,65%. Isolat D berbentuk kristal putih yang memiliki titik leleh 56 , termasuk dalam senyawa golongan terpenoid, memiliki rumus molekul C15H26O dengan massa molekul 222 gram/mol, identifikasi FTIR menunjukkan adanya gugus     O-H, C-H (SP3), C-C metilen (-CH2-CH2), -CH3, dan C-OH alkohol tersier yang merupakan karakteristik dari senyawa patkouli alkohol.Kata Kunci : Daun Nilam (Pogostemon Cablin Benth.), Minyak Atsiri, Patkouli AlkoholThis research aims to determine the amount of patchouli alcohol compound contained in the essential oil of patchouli leaves and the characteristics of the patchouli alcohol compound contained in the essential oil of patchouli leaves. The research sample was taken from Paruttellang Village, Ngapa District, North Kolaka Regency, Southeast Sulawesi Province. This research stage consists of sample preparation, water distillation, fractionation, GC-MS analysis, purification and identification. The results of the research were 57 mL of patchouli leaf essential oil which was light yellow in color and had a distinctive fragrance. Analysis using GC-MS on fraction B, fraction C, fraction D and fraction E resulted in a Patchouli alcohol compound content of 22.71%; 30.13%; 33.09% and 22.65%. Isolate D is white crystals which have a melting point of 56 , included in the terpenoid group of compounds, has the molecular formula C15H26O with a molecular mass of 222 grams/mol, FTIR identification shows the presence of the O-H, C-H (SP3), C-C methylene (-CH2-CH2), -CH3, and C-OH tertiary alcohol which is characteristic of Patchouli alcohol compounds.Keywords: Patchouli Leaves (Pogostemon Cablin Benth.), Essential Oil,  Patchouli Alcohol