bluuebunny/crossref_metadata_2025 huggingface dataset:
Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice
Authors: Freria Camila M. , Hall Jodie C.E. , Wei Ping , Guan Zhen , McTigue Dana M. , Popovich Phillip G.
Published: March 2017

Impaired signaling via CX3CR1, the fractalkine receptor, promotes recovery after traumatic spinal contusion injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the lesion epicenter. Here, we tested the hypothesis that CX3CR1-dependent changes in microglia and macrophage functions also will enhance neuroplasticity, at and several segments below the injury epicenter. New data show that in the presence of inflammatory stimuli, CX3CR1-deficient (CX3CR1−/−) microglia and macrophages adopt a reparative phenotype and increase expression of genes that encode neurotrophic and gliogenic proteins. At the lesion epicenter (mid-thoracic spinal cord), the microenvironment created by CX3CR1−/−microglia/macrophages enhances NG2 cell responses, axon sparing, and sprouting of serotonergic axons. In lumbar spinal cord, inflammatory signaling is reduced in CX3CR1−/−microglia. This is associated with reduced dendritic pathology and improved axonal and synaptic plasticity on ventral horn motor neurons. Together, these data indicate that CX3CR1, a microglia-specific chemokine receptor, is a novel therapeutic target for enhancing neuroplasticity and recovery after SCI. Interventions that specifically target CX3CR1 could reduce the adverse effects of inflammation and augment activity-dependent plasticity and restoration of function. Indeed, limiting CX3CR1-dependent signaling could improve rehabilitation and spinal learning.

SIGNIFICANCE STATEMENTPublished data show that genetic deletion of CX3CR1, a microglia-specific chemokine receptor, promotes recovery after traumatic spinal cord injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the lesion epicenter. Data in the current manuscript indicate that CX3CR1 deletion changes microglia and macrophage function, creating a tissue microenvironment that enhances endogenous repair and indices of neuroplasticity, at and several segments below the injury epicenter. Interventions that specifically target CX3CR1 might be used in the future to reduce the adverse effects of intraspinal inflammation and augment activity-dependent plasticity (e.g., rehabilitation) and restoration of function.
Statistical analyses of digital collections
Authors: Faber Frandsen Tove , Nicolaisen Jeppe
Published: March 2017

Using statistical methods to analyse digital material for patterns makes it possible to detect patterns in big data that we would otherwise not be able to detect. This paper seeks to exemplify this fact by statistically analysing a large corpus of references in systematic reviews. The aim of the analysis is to study the phenomenon of non-citation: Situations where just one (or some) document(s) are cited from a pool of otherwise equally citable documents. The study is based on more than 120,000 cited studies, and a total number of non-cited studies of more than 1.6 million. The number of cited studies is found to be much smaller than the number of non-cited. Also, the cited and non-cited studies are found to differ in age. Very recent studies tend to be non-cited whereas the cited studies are rarely of recent age (e.g. within the same year). The greatest differences are found within the first 10 years. After 10 years the cited and non-cited studies tend to be more similar in terms of age. Separating the data set into different sub-disciplines reveals that the sub-disciplines vary in terms of age of cited vs. non-cited references. Some fields may be expanding and the number of published studies is thus growing. Consequently, cited and non-cited studies tend to be younger. Other fields may be more slowly progressing fields that use a greater proportion of the older literature within the field. These field differences manifest themselves in the average age of references.
Semantic web developments in Hungarian public collections in an international perspective
Authors: Nemeth Marton
Published: March 2017

In my paper after describing the international context of the Hungarian semantic web projects, I would like to introduce the semantic web project of the Hungarian National Széchényi Library. They built up an ontology published their catalogue and authority data as linked open data on the semantic web (by the help of an own name space, SKOS and VIAF). They also generated a SPARQL-endpoint in order to put their semantic datasets to the cloud.A recent project of the Petőfi Literary Museum focusing on name authority record. They are converting around 620000 authority record into RDF-XML format. They would like to publish their data in VIAF (worldwide semantic virtual authority file database) and make them accessible on the OCLC WorldCat semantic environment. This database will be the second database followed by the Hungarian National Library that will appear in VIAF. They are planning also to build up an own triple-store in collaboration with other Hungarian libraries and museums in order to enrich their own semantic datasets with external semantic links.In this context I would like to introduce the tools developed by the framework of the ALIADA project with an international collaboration in order to offer a complete environment to public collection to help them appearing on the semantic web with their own triple-store and datasets. I would like to describe some major projects in semantic field in Hungary that can be implemented possibly in the future. I will mainly highlight the concept of the Hungarian National Namespace that can set all the institutional efforts from public collections to a common framework. Last but not least I would like to describe the use of microformats (based on HTML 5 standard) to put semantic markup data elements into full-text online content resources. That can be also really relevant for public collections (especially for libraries) in order to provide new semantic datasets based on their existing full-text online resources.
Do we need better online book review organisation?
Authors: Jug Tjaša , Žumer Maja
Published: March 2017

Introduction. Online customer reviews present one of the most important factors in book purchasing or borrowing decisions. Given that only well-organized reviews are useful, Amazon has already started linking multiple formats and editions of the same book. Nevertheless, this method is not suitable for books that have appeared in many formats and editions as some attributes do not apply to all versions.Research questions. In our study we were interested in the aspects of a book users perceive as important and the extent to which these attributes match FRBR entities. We were also interested in the relation between specific attributes in the reviews and the numeric rating of the book.Methods. We used content analysis on two random samples of Amazon customer reviews. The sample included a total of 600 reviews of three well-known fiction book titles that have many formats and editions that accommodate the different preferences of readers.Results. The results show that readers take into consideration book information at various abstraction levels that match those in the FRBR model. Most reviewers comment on the book content while review readers consider reviews that comment on different aspects of a book as more helpful.Conclusions. Given that subjective opinion is an important factor in the users’ book selection decision, it would be reasonable to rethink the presentation and organisation of online book reviews.
Managing a digital archiving project at the University of the West Indies Library
Authors: Salmon Frances , Kerr-Campbell Maureen , A Kerr Paulette
Published: March 2017

Digital archiving presents a ready solution to the problem of hidden special collections. The availability of information and communication technology solutions provide libraries, archives and museums with a way forward. However, cost constraints present a real challenge to institutions, especially in the developing world where digitization projects must compete for scarce resources with many other pressing services. In the competition for resources special collections sometimes play second fiddle to immediate services, for example user facilities.The Library of the University of the West Indies (UWI), Mona, faced with limited and declining financial resources, yet recognizing the value of its growing but hidden special collections especially to scholarship at the university, as well as to the cultural and historical significance of the Caribbean region, sought cost-effective and innovative solutions to address the situation and to go ‘global’ with these collections.This paper uses a case study approach and details the strategies employed by a team at the University of the West Indies, Mona Library, including the acquisition of equipment, selection of collections to be included, and digitization of thirty collections of varied formats as well as deliberate collaborative initiatives at training of staff to ensure sustainability. It discusses challenges in the on-going process, and complications alluded to by Prochaska (2009) especially those of legal issues, politics, ownership, and values involved in stewardship of the collections. The paper posits solutions against a background of scarce resources as well as opportunities for far reaching and effective services.
Education for digital libraries
Authors: Aparac-Jelušić Tatjana
Published: March 2017

In the last two decades higher education in Europe has been going through deep changes, based on the vision of united educational space and educational reform as a consequence of many social and technological changes. Although many discussions have been held, many conferences organised, and serious research papers published on the topic of changes, internationalization and Europeanisation of education of information experts, there are still debates on conceptual issues and an urge for a new, innovative approach to structure and organisation of higher education institutions, including information sciences field.The aim of this paper is to point out to new trends in European higher education that have taken place in information sciences as well. These trends have stimulated search for solutions that would, starting from traditional competences and critically approaching new possibilities, enable the offer of attractive and sustainable study programmes that would be flexible enough to react on labour market needs for experts in the digital environment and new educational profiles.
Celiac disease: past, present and future – boundless explorations of a disease of modern times
Authors: Maxim Roxana , Trifan Anca , Plesa Alina
Published: March 2017

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Molecular Analysis of Vascular Endothelial Growth Factor (VEGF) Receptors in EUS-guided Samples Obtained from Patients with Pancreatic Adenocarcinoma*
Authors: Costache Mădălin Ionuț , Iordache Sevastița , Costache Cornelia Alexandra , Dragos Ene , Dragos Alexandru , Săftoiu Adrian
Published: March 2017

Background & Aims: Vascular endothelial growth factor (VEGF) and its receptors (VEGF-R1 and VEGF-R2) are the most important angiogenesis stimulating factors in pancreatic cancer. This study aims to assess VEGF-R1 and VEGF-R2 gene expression in EUS-FNA samples and identify prognostic markers in pancreatic adenocarcinoma.Methods. This was a retrospective study of prospectively collected data of 88 consecutive patients, with clinical and imaging suspicion of pancreatic neoplasms, based on samples obtained through endoscopic ultrasound-guided fine needle aspiration (EUS-FNA).Results. EUS had an accuracy of 93.2% for the diagnosis of pancreatic cancer. Based on real-time qPCR analysis, VEGF-R1 and VEGF-R2 expressions were present in 90% and 65% of the analysed malignant samples, respectively; 89% of the patients died during the study, with a median survival rate of only 9 months. The survival was correlated with the initial stage and with the presence of VEGF-R1 and VEGF-R2 gene expression. We found that there are significant correlations between death/survival and T stage, N stage, resectability status, VEGF-R1, VEGF-R2 and VEGF-R1/VEGF-R2 coexpression. Using a Cox model regression our study demonstrates that VEGF-R1/VEGF-R2 coexpression might be considered as a poor prognostic factor in pancreatic cancer.Conclusions. EUS is a very effective technique for the diagnosis and staging of pancreatic adenocarcinoma in patients with clinical and imaging suspicion of pancreatic neoplasm, with an accuracy of 93.2%. Furthermore, the role of molecular analysis of EUS-guided FNA samples was established by the assessment of VEGF-R1, VEGF-R2 gene expression, which might be considered prognostic markers in pancreatic cancer.Abbreviations: cDNA: deoxyribonucleic acid concentration; CE-EUS: contrast enhanced endoscopic ultrasound; CT: computed tomography; EUS: endoscopic ultrasound; EUS–FNA: endoscopic ultrasound guided fine needle aspiration; IHC: immunohistochemistry; MRI: magnetic resonance imaging; qRT–PCR: quantitative real time polymerase chain reaction; RNA: ribonucleic acid; VEGF: vascular endothelial growth factor; VEGF-R1: vascular endothelial growth factor receptor 1; VEGF-R2: vascular endothelial growth factor receptor 2.
G Protein-Coupled Receptor 30 (GPR30) Expression Pattern in Inflammatory Bowel Disease Patients Suggests its Key Role in the Inflammatory Process. A Preliminary Study
Authors: Włodarczyk Marcin , Włodarczyk Aleksandra Sobolewska , Cygankiewicz Adam I. , Jacenik Damian , Polańczyk Aleksandra Piechota , Michalska Krystyna Stec
Published: March 2017

Background & Aims: G protein-coupled receptor 30 (GPR30) is a recently de-orphanized estrogen receptor that mediates the effects of estrogens on different cells. It has been postulated that in inflammatory bowel diseases (IBD) activation of GPR30 blocks the pathways dependent on pro-inflammatory cytokines. The aim of our study was to investigate GPR30 expression in patients with IBD and its potential implication in future therapies.Methods. Fifty-seven patients were enrolled in our study: 20 subjects with Crohn’s disease (CD), 22 with ulcerative colitis (UC) and 15 controls. In each subject, biopsies were taken from various left-colonic locations. Gene and protein expression of GPR30 was quantified using real time RT-PCR or Western blot.Results: GPR30 mRNA and protein expression were detected in all tested colonic tissues. No significant differences in GPR30 gene expression were observed. In non-inflamed areas, GPR30 protein was strongly increased in CD patients, but moderately in UC patients (p= 0.014 and p=0.143, respectively, vs. controls). In CD patients, a significantly lower GPR30 protein content in inflamed than in non-inflamed tissue was observed (p=0.039). The change was independent of patient gender.Conclusion: Our observations indicate that GPR30 may play a role in the development and progression of inflammatory lesions in IBD, thus affecting disease severity, and consequently IBD treatment. Therefore, GPR30 may become an attractive target for novel anti-IBD drugs, particularly in CD.Abbreviations: CRP: C-reactive protein; C-IBS: constipation-predominant IBS; CD: Crohn’s disease; D-IBS: diarrhea-predominant IBS; ER: Estrogen; GPER: G protein – coupled estrogen receptor 1; GPR30: G protein-coupled receptor 30; GI: gastrointestinal; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; IBD: inflammatory bowel diseases; IL: Interleukin; ICAM-1: intracellular cell adhesion molecule-1; IBS: irritable bowel syndrome; PDL: periodontal ligament; Th: T helper; TNF-α: tumor necrosis factor-α; UC: ulcerative colitis; VCAM-1: vascular cell adhesion molecule-1; WBC: white blood cells.
Antiproliferative and Apoptotic Effects of Lidocaine on Human Hepatocarcinoma Cells. A preliminary study
Authors: Jurj Ancuta , Tomuleasa Ciprian , Tat Tiberiu T. , Neagoe Ioana Berindan , Vesa Stefan V. , Ionescu Daniela C.
Published: March 2017

Background & Aims: It is now well documented that certain anesthetic techniques may influence long term outcome in cancer patients undergoing surgery. More recently, local anesthetics proved certain antiproliferative effects in cancer cells. In our study, we aimed to investigate if lidocaine has antiproliferative effects in human hepatocarcinoma cells and to identify possible mechanisms of these effects.Methods. We investigated the inhibitory effect of different concentrations of lidocaine on the proliferation of cultured HepG2 human hepatocarcinoma cells and LX2 normal liver fibroblasts. Cells were exposed to nine different concentrations of lidocaine for 72h. MTT assay was used to investigate HepG2 and LX2 proliferation while Western blotting was used for detection of p53 expression level.Results. Our data showed that lidocaine inhibited cell proliferation in a concentration-dependent manner in both HepG2 and LX2. The antiproliferative effects of lidocaine in LX2 were significantly diminished as compared with those in HepG2 (p< 0.001). Similarly, the expression level of p53 was significant decreased in HepG2 lines treated with lidocaine as compared with control and LX2 (p = 0.0241).Conclusions. In clinically relevant concentrations, lidocaine had significant antiproliferative effects on human hepatocarcinoma cells. These effects were time and dose-dependent. One of the possible mechanisms of these effects is by modifying the P53 expression level. The relevance of these findings in clinical practice is limited; clinical impact of these effects on the outcome of patients with hepatocarcinoma undergoing surgery or minimal invasive procedures needs to be demonstrated in future animal models and clinical studies.Abbreviations: DMSO: dimethyl sulfoxide; DNA: deoxyribonucleic acid; EDTA: ethylenediaminetetraacetic acid; EGFR: epidermal growth factor receptor; MTT assay: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay; NK cells: natural killer cells; RCTs: randomized controlled studies; VGSC: voltage gated sodium channels.
Pancreatic Solid Pseudopapillary Neoplasm as an Incidental Discovery in a Patient with Rectal Neoplasm
Authors: Bancila Ion , Dumitru Radu , Becheanu Gabriel , Gheorghe Cristian
Published: March 2017

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Reply
Authors: Römkens Tessa E.H.
Published: March 2017

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RETENSI PROTEIN DAN PEMANFAATAN ENERGI PADA BENIH IKAN PATIN JAMBAL (Pangasius djambal) YANG DIBERI PAKAN BERPROTEIN TINGGI
Authors: Suhenda Ningrum , Tahapari Evi , Slembrouck Jacques , Moreau Yann
Published: March 2017

Untuk mempelajari pemanfaatan energi dan retensi protein pada Pangasius diambal, ikan diberi ransum yang kadar proteinnya tinggi, sehingga dapat diketahui berapa jumlah nutriea yang dikonversikan untuk pertumbuhan dan berapa yang dibakar (katabolisme). Benih ikan patin jambal dengan bobot awal rata-rata 6,4 g ditebar dalam tangki serat gelas volume 30 L sebanyak15 ekor ikan per tangki.
BUDIDAYA UDANG WINDU PADA TAMBAK POLA RESIRKULASI MENGGUNAKAN SISTEM TANDON
Authors: Gunarto Gunarto , Muslimin Muslimin , Mansyur Abdul
Published: March 2017

Untuk menjaga agar kondisi perairan tambak budi daya udang tetap baik, maka sistem biofilterdan resirkulasi digunakan dalam penelitian ini. Tujuan penelitian adalah untuk mengetahuiproduksi udang windu pada padat tebar udang yang berbeda dan juga tinjauan terhadap mutu kualitas airnya pada budi daya udang windu pola resirkulasi air semi tertutup menggunakansislem tandon. Penelitian dilaksanakan di Tambak Maranak menggunakan 12 petak masing-masing ukuran 500 ml.
Estrutura funcional de uma semeadora de tração humana
Authors: Stefanello Giusepe , Machado Antônio Lilles Tavares , Reis Ângelo Vieira dos , Machado Roberto Lilles Tavares , Morais César Silva de
Published: March 2017

O milho e o feijão são semeados em praticamente todas as pequenas unidades familiares de produção, normalmente, em sistema convencional de cultivo. Há interesse no sistema de semeadura direta, porém não estão disponíveis semeadoras adequadas às suas necessidades. As semeadoras manuais, utilizadas por esses agricultores, inclusive para semeadura direta, possuem restrições de capacidade e de desempenho operacional, além de problemas ergonômicos. É necessário o desenvolvimento de máquinas desse porte, que garantam maior qualidade na operação de semeadura dessas culturas. O objetivo do presente trabalho foi estabelecer a estrutura funcional de uma semeadora puncionadora de tração humana para semeadura direta de milho e feijão. Foi aplicada uma metodologia sistemática, contemplando análise de especificações, identificação de restrições e estabelecimento das estruturas funcionais em diagrama de blocos. Foi eleita a estrutura funcional de empurrar com um dosador e múltiplos abridores de solo.
Chemical composition and fatty acid profile in meat from grazing lamb diets supplemented with ryegrass hay, fishmeal and soya bean meal as PUFA sources
Authors: Romero-Bernal Jose , Almaraz Ernesto Morales , Ortega Octavio Alonso Castelán , Salas Nazario Pescador , González-Ronquillo Manuel
Published: March 2017

ABSTRACT: This study examined the characteristics of the fatty acids profile in the meat of lambs fed grazing and supplemented with different PUFA sources. Thirty Suffolk lambs were used (37.2±5.4kg BW), grazing on perennial ryegrass (Lolium perenne) (12h d-1) and supplemented (30g kg-1 BW0.75) with ryegrass hay (RGH), or supplements formulated with fishmeal (FHM) or soybean meal (SBM). Lambs were used in a completely randomized design. Results showed an effect on total SFA, with SBM higher than RGH (P=0.033), and SBM and FHM showing higher MUFA content compared with RGH (P=0.001). Total PUFA content was higher for RGH, followed by FHM and with the lowest content for SBM (P=0.001). Concluding that there is a variation in fatty acid content depending on the lipid-protein source used in supplementation in grazing sheep, the content of PUFA was higher for grazing lambs supplemented with RGH compared with those supplemented with FHM or SBM.
Modelagem nos anos iniciais da educação básica: como os estudantes modelam situações-problema?
Authors: Scheller Morgana , Bonotto Danusa de Lara , Madruga Zulma Elizabete de Freitas , Biembengut Maria Salett , Sánchez Jose Maria Chamoso
Published: March 2017

Resumo: Neste artigo objetiva-se compreender e analisar como estudantes dos Anos Iniciais da Educação Básica, em atividade de Modelagem, resolvem situações-problema que podem requerer domínio algébrico simbólico e que linguagens fazem uso na expressão dos modelos. Os dados empíricos advieram de uma das práticas de Modelagem desenvolvidas com 16 estudantes de escola pública durante 11 horas/aula, no período de junho e julho/2015 e foram obtidos dos materiais produzidos pelos estudantes, gravações de áudio e vídeo e observação realizada durante a prática sobre a numeração do calçado de uma pessoa. No processo os estudantes propuseram modelo estabelecendo relações numéricas entre as variáveis, obtendo generalização e realizando previsões. A análise evidenciou que eles resolvem situação-problema apresentando modelos nas linguagens natural, numérica e tabular, evidenciando domínio algébrico característico do pensamento algébrico anterior à linguagem simbólica, pertinente ao nível de escolaridade, e extrapolam objetivos referentes a realização de previsão a partir do modelo.
A new species of Leiostracus from Bahia, Brazil (Gastropoda, Pulmonata, Orthalicidae)
Authors: Salvador Rodrigo B. , Cavallari Daniel C.
Published: March 2017

A remarkable new species of pulmonate snail was recently collected in a small Atlantic Rainforest fragment near the city of Canavieiras, state of Bahia, Brazil, an area known for a high diversity of land snails. It is described herein as Leiostracus fetidus sp. nov. and can be easily identified by its color pattern of irregular brown to black axial stripes on a white to yellow background, a reddish axial band "separating" the white peristome from the rest of the shell and a broad brown spiral band surrounding the umbilical region. Other diagnostic features include a relatively small size, a proto columellar fold and two very weak folds delimiting the basal region of the aperture. This discovery is a reminder of how little this fauna is known and also an alarm for proper conservation of these forest fragments.
Construção de uma maquete de sistema planetário como atividade auxiliar ao ensino de astronomia nos cursos de física
Authors: Lima Filho Joaquim Brasil , Silva Marina Luz da , Madureira Hunos Paixão , Ibiapina Rawlinson Medeiros
Published: March 2017

Objetivando complementar a discussão sobre o sistema solar, apresentamos uma maquete construída a partir de material de baixo custo e que tem a finalidade de oferecer aos alunos uma visão espacial e dinâmica dos movimentos dos planetas. Trata-se de uma maquete do sistema solar em que as posições dos planetas podem ser manualmente variadas de acordo com as leis de Kepler. Com isso, propomos tornar mais compreensível a dinâmica dos corpos celestes ao expor de uma maneira tátil e observacional a relação entre seus movimentos reais e seus movimentos aparentes observados pelos astrônomos quando estudam o céu noturno a olho nu. Associado a uma discussão sobre a astronomia, partindo de uma contextualização histórica desde os antepassados até a atualidade, o uso da maquete favorece a compreensão dos motivos que levaram aos erros e acertos dos modelos de sistema celeste propostos até o modelo atualmente aceito. Para que a construção da maquete seja viável, são apresentados todos os parâmetros necessários, tais como as distâncias dos planetas ao Sol e as ferramentas matemáticas para obtenção dos valores na escala da maquete.
Contribuição para o conhecimento do sistema radicular da pupunheira (Bactris gasipaes H. B. K. - Guilielma gasipaes (H.B.K.) Bailey). I- Solo Latossolo Amarelo, textura média ()
Authors: Ferreira Sidney Alberto do Nascimento , Clement Charles Roland , Ranzani Guido
Published: March 2017

Resumo Relativamente poucos são os conhecimentos agronômicos que se dispõe sobre a exploração racional da pupunheira. Dentre esses conhecimentos, a distribuição do sistema radicular é essencial, para o planejamento de sistemas de produção. No presente trabalho, os autores utilizaram o método de tradagens para retirar amostras da massa radicular de sete pupunheiras de 2 a 9 troncos por pé. As amostras foram separadas, lavadas, secadas e pesadas, com o objetivo de caracterizar a distribuição do sistema radicular em um Latossolo Amarelo, textura média com horizonte Ap fraco. Foi verificado que 58% do total da massa radicular se localiza nos primeiros 20 cm do solo e ainda que 53% (48% copa individual) do total se encontrou nessa camada, dentro da projeção da copa. Verificou-se ainda que 89% (82% copa individual) do total da distribuição radicular se encontraram dentro do diâmetro da copa até mais de 200 cm de profundidade.
Rhadinorhynchus plagioscionis n. sp. (Acanthocephala: Rhadinorhynchidae) da pescada (Plagioscion Squamosissimus) da Amazônia Brasileira
Authors: Thatcher Vernon E.
Published: March 2017

Resumo Rhadinorhynchus plagioscionis n. sp. (Acanthocephala: Rhadinorhynchidae) é descrita do intestino da pescada (Plagioscion squamosissimus (Heckel), obtida perto de Manaus, Amazonas, Brasil. A nova espécie distingue-se das demais espécies do gênero por ter espinhos no tronco com raízes bifurcadas e pontas livres. A distribuição destes espinhos é também diferente, sendo contínua desde o pescoço até a parte posterior aos testículos no macho e bem posterior à campainha uterina na fêmea. A nova espécie tem 12 fileiras de ganchos na probóscide, no sentido longitudinal, com 23 e 24 ganchos por fileira, alternando. No número de ganchos na probóscide, a nova espécie aproxima-se mais da R. trachuri Harada, 1935, de um peixe marinho japonês. R. plagioscionis distingue-se dessa espécie nor ter glândulas de cimento que são longas e tubulares (não curtas e em forma de garrafa); lemniscos mais curtos (não mais compridos) que a bainha da probóscide; ovos maiores e um hospedeiro de água doce. A nova espécie é a terceira a ser encontrada em hospedeiro de água doce no mundo.
Ecologia de plântulas de Pithecolobium racemosum Ducke. 1 - Número de distribuição dos individuos
Authors: Leite Angela M. C. , Rankin Judy M.
Published: March 2017

Resumo As plântulas de Pithecolobium racemosum ocorrem em quantidades diferentes de acordo com o grau de perturbação das áreas. Nas áreas mais perturbadas, a tendência é o aumento do número de plântulas, o que, por sua vez, está associado à maior luminosidade. Outro fato notório nesta espécie é a agregação das plântulas em todas as áreas raleadas ou densas, variando o tipo de agregação segundo o raleamento. Populacionalmente, entretanto, as plântulas de P. racemosum apresentam o mesmo comportamento em todos os graus de perturbação, isto é. ocorrem em maior quantidade sob as copas das árvores matrizes, além da distribuição em agregação e da pouca ou nenhuma variação no número de indivíduos comparados em dois anos. Ressalta-se ainda o domínio dos adultos parentais sobre os seus regenerantes, fato este de importância estrutural para o manejo florestal. Por fim, pode-se dizer que P. racemosum tem comportamento de espécie não tolerante à sombra ou de espécie de mata colonizadora de clareiras.
Guatteriopsis friesiana W. Rodrigues, nova espécie de Annonaceae para a Amazônia
Authors: Rodrigues William A.
Published: March 2017

Resumo Guatteriopsis friesiana W. Rodrigues (Annonaceae), arvoreta relativamente freqüente nas matas de terra firme das cercanias de Manaus. Amazonas, Brasil, é descrita neste trabalho como espécie nova. Inclui este artigo uma chave sinótica para identificação das espécies de Guatteriopsis até então conhecidas
Área de Vertebrados do Museu Paraense Emílio Goeldi
Authors: Novaes F. C. , Cunha O. R.
Published: March 2017

Resumo Breve relato das atividades da área de Vertebrados do Museu Paraense Emílio Goeldi quando passou em janeiro de 1955 a ser administrado pelo Conselho Nacional de Pesquisas. As principais coleções científicas são a de mamíferos com cerca de 9.000 exemplares. Aves com 37.718 e Herpetologia 35.000 exemplares.
Aspectos fenológicos, ecológicos e de produtividade da sorva (Couma utilis Muell. Arg.)
Authors: Falcão Martha de Aguiar , Lleras Eduardo
Published: March 2017

Resumo São aqui apresentados aspectos da fenología, ecologia e de produtividade da Sorva (Couma utilis Muell Arg.). Em Manaus, a espécie floresce e inicia a frutificação na época mais chuvosa com a safra no periodo seco. Foram encontradas onze espécies de insetos visitantes, sendo dez Apiidae e uma Heliconiidae. Postula-se a não existência de um polinizador específico para a espécie. O número de flores variou entre 21.000 a 47.000 para as dez árvores com uma taxa de formação de frutos entre 10 e 15%. Foram encontradas correlações muito altas entre o número de flores e outros parâmetros de produção tais como número de frutos verdes, frutos maduros e peso da safra, o que sugere que outros fatores além dos polinizadores podem desempenhar papel importante na determinação da safra.
Influence of body posture on the association between postpartum depression and pain
Authors: Angelo Rita di Cássia de Oliveira , Silva Denila Coelho da , Zambaldi Carla Fonseca , Cantilino Amaury , Sougey Everton Botelho
Published: March 2017

OBJECTIVE: To determine the association between postpartum depression (PPD), intensification of back pain and exacerbation of changes in postural alignment intrinsic to puerperium. METHODS: Eighty women at 2 to 30 weeks postpartum were included in the study according to the following criteria: literate mothers, gestation of 34 to 42 weeks, and healthy live-born infants. All mothers agreed to participate in the study. Depressive symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS). Pain was assessed using a visual analogue scale (VAS) and the Nordic Musculoskeletal Questionnaire (NMQ), and posture, using real time naturalistic observation. RESULTS: There was a statistically significant association between PPD and pain intensity (p = 0.002). The upper back was the most frequent pain site among depressed women, both before (p = 0.04) and after delivery (p = 0.01). There were no associations between PPD and type of posture (p = 0.328). However, pain intensity was greater among depressed women in the swayback group (p < 0.001). CONCLUSION: The intensification of puerperal pain is closely associated with PPD. Our results suggest that back pain may be both a risk factor and a comorbidity of PPD among puerperal women and that pain and type of posture are interdependent.
Pater, pátria e a memória como patrimônio: sobre K.: relato de uma busca, de Bernardo Kucinski
Authors: Russo Vincenzo
Published: March 2017

resumo Existe uma memória de gênero? Existe uma memória masculina e/ou feminina? E o que acontece quando as memórias de um pai resgatam (ou tentam resgatar) a fragmentariedade das experiências da filha articuladas num tempo pessoal e subjetivo mas pontuadas pelos tempos traumáticos da História, ainda por mais da História da Pátria, da história-pátria? K.: relato de uma busca, de Bernando Kucinski, representa um dispositivo não só literário para tentar ensaiar algumas destas questões, como as da memória ou da pós-memória do supérstite, que são centrais no debate contemporâneo brasileiro.
A double-antibody sandwich ELISA based on the porcine circovirus type 2 (PCV2) propagated in cell culture for antibody detection
Authors: Cruz Taís F. , Kanashiro Tatiana M. , Castro Alessandra M.M.G. de , Baldin Cintia M. , Richtzenhain Leonardo J. , Araujo Jr João P.
Published: March 2017

ABSTRACT: Few studies have described enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies against porcine circovirus type 2 (PCV2) based on antigens produced in cell culture. Furthermore, few articles have described viral purification techniques for members of the family Circoviridae. This occurs because circoviruses are difficult to isolate, noncytopathogenic, and produce low viral titres in cell culture. Thus, for overcoming these difficulties in the cultivation of PCV2, this study aimed to develop a double-antibody sandwich ELISA based on the cell culture antigen PCV2b for the quantification of anti-PCV2 antibodies. A 20% and 50% discontinuous sucrose cushion was used for viral purification, which enabled the separation of cell culture proteins in the 20% sucrose cushion and a greater viral concentration in the 50% sucrose cushion. Following isopycnic centrifugation, PCV2 was concentrated in the band with density values from 1.330 to 1.395g/cm3. Viral purification was assessed using SDS-PAGE, indirect ELISA and electron microscopy. The standardised ELISA revealed a strong linear correlation (r= 0.826, p<0.001) when compared with a commercial ELISA kit. The assay exhibited low variability (inter-assay coefficient of variation of 4.24% and intra-assay of 1.80%) and excellent analytical specificity conferred by the capture antibody produced in rabbit. Thus, this ELISA is a rapid, specific and convenient method for the detection of antibodies against PCV2 in studies of experimental and natural infection, and in monitoring the response to vaccination on commercial farms.
Avaliação de parâmetros bioquímicos séricos em Tartarugas-da-Amazônia (Podocnemis expansa) mantidas em cativeiro
Authors: Fonseca Leandro A. , Maia Natasha L. , Girardi Fabrícia M. , Carvalho Filho Wilson P. , Pimentel Filippe G. , Braga Fábio R.
Published: March 2017

RESUMO: Amostras de sangue de Tartaruga-da-Amazônia mantidas em cativeiro foram analisadas com o propósito de avaliar os constituintes bioquímicos séricos e de relacionar ao que já foi relatado por outros pesquisadores, além de gerar mais informações, tendo em vista a escassez de dados envolvendo a espécie estudada. Foram utilizados 35 animais, com idade entre 3 e 7 meses, os quais foram contidos fisicamente para coleta de sangue em tubo sem anticoagulante. As análises bioquímicas foram processadas através de métodos cinéticos (enzimas) e colorimétricos (demais análises), e os valores médios obtidos foram: cálcio 7,0±1,9mg/dL, fóforo 2,8±1,2mg/dL, ácido úrico 1,8±0,8mg/dL, uréia 10,4±3,9mg/dL, alanina aminotransferase (AST) 75,5±33,6 UI/L, proteína total 1,9±0,8g/dL, triglicerídeos 22,9±9,8mg/dL e colesterol 45,3±19,7mg/dL. Observou-se que os valores dos componentes séricos avaliados assemelham-se aos que foram encontrados por outros pesquisadores em estudos bioquímicos séricos com Podocnemis expansa e outras tartarugas de água doce. Importante ressaltar que, no decorrer deste estudo observou-se a escassez de dados publicados sobre parâmetros sanguíneos de tartarugas do gênero Podocnemis, especialmente a espécie Podocnemis expansa, o que corroborou a alta relevância do desenvolvimento de mais pesquisas que envolvam a questão.
Migration and maternal health: experiences of brazilian women in Portugal
Authors: Almeida Ligia Moreira , Caldas Jose Peixoto
Published: March 2017

OBJECTIVES: to characterize maternal and neonatal healthcare provided to Brazilian population, assessing key factors: access, use and quality of care received during this period. The goal was to assess possible differences regarding women's perceptions regarding the quality and appropriateness of care received, providing qualitative information, as part of a holistic perspective. METHODS: the present study adopted a qualitative methodology (semi-structured interviews) for collecting and analyzing data. Possible differences in women's perceptions regarding the quality and appropriateness of care received were assessed, providing qualitative information, as part of a holistic perspective. The present study was based on privileged information obtained from Brazilian women, residing in the metropolitan area of Porto, regardless of their legal status. RESULTS: a certain dissatisfaction emerged among Brazilian women regarding the quality of information provided by health professionals, the communications skills of these professionals, in addition to a perception of reduced access to medical specialties, especially in primary care. Misinformation about legal rights and inappropriate clarification during medical appointments were frequently reported and interacted with social determinants to result in poorer medical care. CONCLUSIONS: special attention should be given to the specific needs and understanding of immigrants during pregnancy and motherhood in order to improve healthcare. New challenges tend to lie not only in ensuring access, but mostly in promoting equity, as away of providing high-quality care for all.
Resultados de um Programa Multidisciplinar de Otimização do Uso de Antimicrobianos
Authors: Lobo Letícia Gomes , Ramos Fabiano , Moretti Miriane Melo , Alves Paola Hoff
Published: March 2017

Justificativa e Objetivo: O objetivo deste estudo foi avaliar os resultados do PCA desenvolvido pelo Serviço de Controle de Infecção de um hospital universitário do sul do país no período de janeiro/2013 a julho/2014. Métodos: O PCA é desenvolvido por dois médicos infectologistas e uma farmacêutica. São avaliadas todas as prescrições de carbapenêmicos, vancomicina, polimixina B, daptomicina, tigeciclina, linezolida, voriconazol, micafungina e anfotericina b complexo lipídico. Na necessidade de intervenção a mesma é realizada por telefone com orientação ao prescritor ou alerta no prontuário eletrônico. Além disso, são realizados rounds com as equipes de terapia intensiva cardíaca (UTI-CV) para discussão de caso. Resultados e Conclusão: Foram avaliadas 5118 prescrições, com uma média de 297 prescrições mês. O percentual de solicitação de culturas no semestre 1 (janeiro-junho/13), 2 (julho-dezembro/13) e 3 (janeiro-julho/14) foi respectivamente: 25%, 35% e 83%. Foram realizadas em média 70 intervenções/mês, onde o percentual de aceite das intervenções, no semestre 1,2 e 3 foi respectivamente: 61%, 70% e 84%. A dose diária definida (DDD) de meropenem na UTI-CV no período foi de 231,4 DDD/1000 paciente-dia no semestre1, 108,13 DDD/1000 paciente-dia no semestre 2 e 83,79 DDD/1000-paciente-dia no semestre 3.Nossos dados permitem concluir que ações como: incentivo ao tratamento dirigido (coleta de culturas), educação e feedback ao prescritor (orientando o uso racional) e participação ativa em rounds juntos as equipes assistenciais podem ser estratégias na luta contra a resistência.
Teaching EFL in Saudi Arabian Context: Textbooks and Culture
Authors: Aldera Abdullah Saad
Published: March 2017

This article analysed the impact of foreign (L2) cultures on EFL students in Saudi universities. The investigation has been carried out on the basis of theoretical background study, an analysis of the prescribed textbooks and a survey of the L2 learners' attitudes. The research samples include two course books, Access and Interaction1 published by McGraw-Hill Education, and students of English Department, Najran University, KSA. A thorough analysis of the contents of the series showed that the textbooks largely ignore local culture (L1) and include mainly foreign cultures and cultures of other nationalities. The overall results of the survey demonstrated thatL2 learners disagree with the dominance of foreign culture in their course books. However, they simultaneously showed a very positive attitude towards foreign cultures that do not contradict with Saudi social values. This article, therefore, sought to address the cultural bias in the course books and consequent grassroots discontent among L2 learners. The findings of the study are expected to help both ELT specialists and the concerned authority in KSA to select and design textbooks which are suitable for effective pedagogy and tolerably compatible with L1 values and culture.
A New Model and Its Practice in Language Learning Strategy Training
Authors: Gao Li , He Yun , Zeng Jie
Published: March 2017

Learning will be facilitated if students are explicitly trained to become more aware of and proficient in the use of a broad range of strategies that can be utilized in the language learning process. A new learning strategy training model, TCLTSP Model, is designed, focusing on the understanding of learners themselves, understanding the target, and understanding learning strategies, aiming at taking conscious control of learning process. Two examples – learner preference and vocabulary learning strategy training class are demonstrated to illustrate how to practice this model in authentic classes.
Effect of Elementary EFL Learners’ Negotiation on Their Classroom Participation and Grammatical Achievement
Authors: Saboonchi Fatemeh , Mahmoudi Asgar
Published: March 2017

The principal concern of the present study was to explore the effects of two types of negotiation (group work and pair work) on the degree of elementary EFL students’ participation and its corollary impact on their grammatical achievement. Both classes in the study received grammar instruction for twenty sessions. The learners took two grammar tests before and after the treatment in the multiple-choice format. The results showed that negotiation in pairs leads to less participation but better grammatical achievement. In other words, while students in the group work negotiated more, their grammatical achievement was significantly less than the students in the pair work who participated less. It could be concluded, therefore, that while group work leads to more participation, higher grammatical knowledge is possible to be obtained by less participative students.
EFL Teachers' Reflective Teaching, Use of Motivational Strategies, and Their Sense of Efficacy
Authors: Nosratinia Mania , Moradi Zahra
Published: March 2017

The present study aimed at systematically investigating the relationship among EFL teachers' Reflective Teaching (RT), Use of Motivational Strategies (UMS), and Sense of Efficacy (SE). The participants of the study were 194 male and female EFL teachers, between 20 to 30 years of age (Mage = 25) and with 1 to 10 years of teaching experience. The participants were asked to fill out three questionnaires: the RT questionnaire by Akbari, Behzadpour, and Dadvand (2010), the questionnaire of UMS by Cheng and Dörnyei (2007), and the questionnaire of SE by Tschannen-Moran and Woolfolk Hoy (2001). Analyzing the data through running the non-parametric Spearman's rank order coefficient of correlation indicated that there was a significant and positive correlation between RT and UMS, RT and SE, and between UMS and SE. Furthermore, running a multiple regression analysis revealed that RT could more significantly predict the SE among EFL teachers. Regarding the limitations and drawing upon the findings, the article concludes with some pedagogical implications and some avenues for future research.
LE TERME « ÉCOTOURISME » ET SES QUASISYNONYMES DANS L’ESPACE MÉDIATIQUE FRANÇAIS
Authors: MARTINEZ Christine
Published: March 2017

RÉSUMÉ. L’évolution du lexème écotourisme dans les quotidiens français (version informatisée) est le but de notre étude. Nous nous référons à Moirand (2007, p. 4) pour voir ce qui se passe « dans et par les médias » et à Charaudeau et Maingueneau (2002, p. 324) pour la mémoire des discours. Non seulement l’usage et les conditions sociales sont importants dans l’appréciation, la compréhension et la manière, dont sont présentées nos collocations, mais surtout le contexte dans lequel elles évoluent. Qu’il soit écologique, officiel (Ministère de l’Ecologie, du Développement durable et de l’Énergie) ou journalistique (slogan de propagande écologique), ces contextes nous paraissent essentiels pour une bonne compréhension. Notre but est l’analyse de ce phénomène. Le concept de écotourisme est riche en traits sémantiques, et malléable suivant les contextes et les visées médiatiques qu’on lui impose. Nous allons essayer d’approfondir ces singularités dans cet article. Mots-clés : collocation, contexte, discours, écotourisme, journaliste, manipulation, trait sémantique, visée discursive.  ABSTRACT. The evolution of the lexeme ecotourism in French newspapers (electronic version) is the aim of our study. We refer to Moirand (2007, p. 4) to see what happens "in and through the media" and Patrick Charaudeau et Maingueneau (2002, p. 324) for the memory of the speech. Not only the use and social conditions are important in the appreciation, understanding and speaking, which are presented our collocations, but especially the context in which they operate. It is environmentally friendly, official (Ministry of Ecology, Sustainable Development and Energy) or journalistic (ecological propaganda slogan), these contexts we consider essential for a proper understanding. Our ambition is to analyse this phenomenon. The concept of ecotourism is rich in semantic traits and malleable depending on the context and media referred imposed on it. We will try to deepen these singularities in this article. Keywords: collocation, context, discourse, ecotourism, journalist, manipulation, semantic trait, discursive aim.
FIBROMA OSSIFICANTE CENTRAL EM MANDÍBULA: RELATO DE CASO
Authors: Lima Junior Francisco de Assis Almeida , Cunha John Lennon Silva , Rosa Candice Rebouças , Fonte Juliana Batista Melo , Melo Maria de Fátima Batista , Albuquerque Junior Ricardo Luiz Cavalcanti
Published: March 2017

O Fibroma Ossificante Central (FOC) é uma neoplasia benigna de origem fibro-óssea incomum que acomete os ossos da face, caracterizado pela substituição da arquitetura óssea normal por tecido conjuntivo rico em fibroblastos e fibras colágenas, com deposição de material mineralizado em quantidade e morfologia variada. Estudos tem demonstrado a existência de muita superposição entre os aspectos clínicos, imaginológicos e histopatológicos das lesões fibro-ósseas benignas dos maxilares, determinando dificuldades no estabelecimento de um diagnóstico seguro. O objetivo deste trabalho foi relatar um caso de FOC em uma localização incomum, com ênfase na discussão de sua etiopatogênese e critérios de diagnóstico diferencial imaginológico e histopatológico entre esta entidade e a outras lesões fibro-ósseas dos maxilares, como a displasia óssea fibrosa e o fibroma ossificante juvenil agressivo.  A análise do caso e sua relação com a literatura vigente permitiu concluir que é de extrema relevância que o diagnóstico do FOC seja devidamente embasado numa correlação de achados clinicopatológicos para assegurar o estabelecimento do diagnóstico e terapêutica mais apropriados.