bluuebunny/crossref_metadata_2025 huggingface dataset:
Personal Higiene, Ketersediaan Air, dan Sanitasi Lingkungan dengan Kejadian Stunting pada Balita Usia 6–59 Bulan di Wilayah Kerja Puskesmas Singorojo I, Kabupaten Kendal
Authors: Pradana Veramita Nanda , Suparmi Suparmi , Ratnawati Ratnawati
Published: September 2023

Latar Belakang: Stunting adalah masalah gizi kronis di Indonesia yang belum tertangani dengan baik. Peningkatan angka kejadian stunting di Indonesia dipengaruhi oleh berbagai faktor seperti faktor maternal, gizi, sosio ekonomi, dan lingkungan. Personal higiene Ibu dan anak, akses ke sanitasi dasar dan air bersih berhubungan dengan tingginya angka stunting di wilayah kerja Puskesmas Singorojo 1 Kabupaten Kendal.
Tujuan: Mengetahui hubungan antara personal higiene, ketersediaan air, dan sanitasi lingkungan dengan kejadian stunting pada balita usia 6–59 bulan.
Metode: Analitik observasional memakai desain case-control. Pengambilan data dilakukan melalui interview menggunakan kuesioner dan observasi pada anak. Populasi terjangkau dari penelitian ini adalah balita usia 6-59 bulan di wilayah kerja Puskesmas Singorojo 1. Sampel yang digunakan berjumlah 50 balita yang berusia 6-59 bulan. Teknik sampling dilakukan secara consecutive sampling. Analisis data memakai uji Chi-Square, Fisher Exact, dan Regresi Logistik.
Hasil: Hubungan personal higiene (OR=5,762; p=0,012; 95% CI=1,363–24,362), ketersediaan air (OR=4,571; p=0,349; 95% CI=0,473–44,170), dan sanitasi lingkungan dengan kejadian stunting (OR=9,333; p=0,001; 95% CI=2,431–35,839). Hasil analisis multivariat hubungan personal higiene (OR=3,867; p=0,111; β=1,353; 95% CI=0,732–20,423), ketersediaan air (OR=10,305; p=0,066; β=2,333; 95% CI=0,858–123,732), dan sanitasi lingkungan dengan kejadian stunting (OR=10,535; p=0,002; β=2,355; 95% CI=2,419–45,887).
Kesimpulan: Personal higiene dan sanitasi lingkungan berhubungan dengan kejadian stunting pada balita usia 6–59 bulan.
Hubungan Tingkat Konsumsi Makan dan Aktivitas Fisik dengan Status Gizi Anggota Ekstrakurikuler Paskibraka
Authors: Hidayanti Fitria , Soeyono Rahayu Dewi
Published: September 2023

Latar Belakang: Indonesia memiliki pasukan pengibar bendera pada kegiatan upacara kemerdekaan yang dikenal sebagai Paskibraka. Status gizi baik merupakan salah satu syarat yang harus dipenuhi untuk menjadi Paskibraka. Tingkat konsumsi makan dan aktivitas fisik menjadi faktor yang berpengaruh terhadap status gizi.
Tujuan: Kajian ini bertujuan untuk melihat korelasi tingkat konsumsi makan dan aktivitas fisik terhadap status gizi anggota ekstrakurikuler Paskibraka SMAN 1 Bangkalan, Indonesia.
Metode: Penelitian ini merupakan jenis penelitian kuantitatif korelasional menggunakan pendekatan cross-sectional. Metode total sampling mengambil sampel sebanyak 56 siswa ekstrakurikuler Paskibraka, berusia 15-16 tahun. Variabel bebas penelitian meliputi tingkat konsumsi makan dan aktivitas fisik, variabel terikatnya yaitu status gizi. Instrumen yang digunakan yaitu kuesioner identitas responden, kuesioner SQ-FFQ (Semi Quantitative Food Frequency Questionnaire) dan kuesioner GPAQ (Global Physical Activity Questionnaire. Data dianalisis menggunakan korelasi Rank Spearman.
Hasil: Tingkat konsumsi makan siswa normal (energi=76,8%, protein=58,9%, lemak=73,21%, karbohidrat=69,64%) dengan 75% sampel memiliki aktivitas fisik sedang dan 89,29% sampel memiliki status gizi baik. Tingkat konsumsi makan (energi p=0.011, lemak p=0.024 dan karbohidrat p=0.003) memiliki korelasi terhadap status gizi, tetapi tingkat konsumsi protein (p=0.141) dan aktivitas fisik (p=0.626) tidak memiliki korelasi terhadap status gizi siswa.
Kesimpulan: Tingkat konsumsi makan (energi, lemak dan karbohidrat) memiliki korelasi terhadap status gizi, tetapi tingkat konsumsi protein dan aktivitas fisik tidak. Penting  bagi seorang siswa ekstrakurikuler Paskibraka untuk selalu memperhatikan tingkat konsumsi makan dan aktivitas fisik disetiap harinya agar memiliki status gizi yang baik.
Apakah Asupan Natrium Berlebih Merupakan Faktor Risiko Overweight?: Tinjauan Sistematis
Authors: Furqonia Annisaa Wulida , Farapti Farapti , Notobroto Hari Basuki
Published: September 2023

Latar Belakang: Konsumsi garam dunia melebihi hingga 200% dari rekomendasi harian. Obesitas merupakan masalah kesehatan terbesar ketiga didunia. Berbagai penelitian mulai menggali mekanisme potensial hubungan antara asupan natrium dengan peningkatan berat badan, risiko kelebihan berat badan dan obesitas.
Tujuan: Menganalisis hubungan antara asupan natrium dengan risiko kelebihan berat badan ditinjau dari status gizi, obesitas sentral dan komposisi tubuh pada populasi dewasa.
Metode : Penelitian ini merupakan tinjauan sistematis. Proses pengumpulan data menggunakan database Pubmed dan Science  Direct dengan kata kunci “obese” OR “overweight” OR “adiposity” AND “sodium” OR “salt intake” AND “adult”. Artikel dipilih melalui seleksi judul dan abstrak yang kemudian diseleksi kembali sesuai dengan kriteria inklusi dan eksklusi.
Ulasan: Terdapat 11 literatur terkait status gizi, 10 literatur terkait obesitas sentral, 3 literatur terkait komposisi tubuh. Asupan natrium  berhubungan dengan peningkatan berat badan dan risiko kelebihan berat badan peningkatan berat badan hingga 2,75 kg, peningkatan lingkar pinggang hingga 2,15 cm dan peningkatan massa lemak hingga 0,91 kg. Mekanisme potensial yang mendasari hubungan ini antara lain dimediasi dengan asupan energi, peningkatan volume ekstraseluler, peningkatan adipositas, dan perubahan leptin plasma.
Kesimpulan: Terdapat hubungan konsumsi garam berlebih dengan peningkatan berat badan dan faktor risiko kelebihan berat badan dilihat dari status gizi, obesitas sentral dan komposisi tubuh pada populasi orang dewasa. Namun, mekanisme terjadinya hubungan tersebut masih perlu dipelajari lebih lanjut.
Pengelolaan Diet dengan Kondisi Disfagia pada Pasien Stroke: Literature Review
Authors: Mangalik Gelora , Laurensia Anggita Raharjani , Ariestiningsih Ayuningtyas Dian
Published: September 2023

Latar Belakang: Disfagia sebagai kondisi yang sering ditemui pada pasien stroke dan merupakan tantangan perawatan karena dapat meningkatkan risiko kekurangan gizi yang dapat menyebabkan komplikasi dan meningkatkan lama perawatan di rumah sakit.
Tujuan: Mengetahui pengelolaan diet dengan kondisi disfagia pada pasien stroke melalui review hasil penelitian sebelumnya.
Ulasan: Pengelolaan diet dengan kondisi disfagia pada pasien stroke diambil dari artikel yang mengulas skrining gizi, asesmen gizi, pemberian makan tinggi energi tinggi protein, pembatasan energi untuk penurunan berat badan, dan penyediaan protein untuk mempertahankan massa otot. Preskripsi diet yang diberikan yaitu penyesuaian energi dan protein, penyesuaian protein, penyesuaian cairan, pemberian suplemen gizi, penyesuaian bentuk makanan, dan rute pemberian makanan. Food preparation program menggunakan penilaian kuesioner Dietary Well-being yang terdiri dari 21 pertanyaan terbagi menjadi 4 kategori yaitu fisik (5 pertanyaan), psikologis (6 pertanyaan), emosional (5 pertanyaan), dan sosial (5 pertanyaan). Komparasi pengental Modified Starch (MS) dan Xanthan Gum (XG) dengan menggunakan penilaian Volume-Viscosity Swallow Test (V-VST) dan Videofluoroscopic (VFS) untuk melihat keamanan menelan pada pasien stroke.
Kesimpulan: Pengelolaan diet dengan kondisi disfagia pada pasien stroke dapat memperbaiki status gizi, fungsi fisik, kemampuan menelan, dan menurunkan lama perawatan di rumah sakit. Food preparation program menunjukkan hasil signifikan pada kuesioner Dietary Well-being kelompok kontrol terutama pada kategori psikologis, emosional, dan sosial. Pengental MS dan XG meningkatkan keamanan menelan pada pasien stroke.
Improvement of Cadres' Skills and Knowledge to Provide Comprehensive Health Services for the Elderly
Authors: Djuari Lilik , Linda Dewanti  , Sulistiawati  , Natasya Nurvita Brilianti  , Farhan Nurdiansyah  , Subur Prajitno
Published: September 2023

Highlights:

Due to the increasing elderly population in Indonesia, this study must address the knowledge and skill gaps among health cadres in a number of Integrated Health Posts for the Elderly (Pos Layanan Terpadu Lanjut Usia/ Posyandu Lansia). 
Through this study, the health cadres increased their knowledge and skills, enabling them to provide comprehensive health services for the elderly. 

Abstract
Numerous issues have arisen as a result of the large size and rapid growth of the elderly population, attesting to the need for serious efforts from all sectors to enhance their welfare. However, the health cadres at the Integrated Health Post for the Elderly (Pos Layanan Terpadu Lanjut Usia/ Posyandu Lansia) lacked the training that would have equipped them with the necessary knowledge and skills to carry out their duties. This study aimed to evaluate the significance of training for enhancing the cadres' knowledge and skills in providing comprehensive health services for the elderly. This study was quasi-experimental research with a pre-test and post-test design. The data analysis was performed using the Shapiro-Wilk test (p>0.05) and the Wilcoxon test (p<0.05). A total of 30 health cadres at Songgon Community Health Center were measured for their levels of knowledge and skills before and after the training. The training included filling out health evaluation charts, providing leaflets containing health counseling materials for the elderly, practicing exercise for the elderly, and singing an elderly marching song. Before filling out the health evaluation chart, the cadres had to measure the elderly's degree of independence as well as their mental, emotional, and nutritional status. The cadres also had to measure the weight, height, and blood pressure of the elderly. Prior to training, the cadres' knowledge of hospitalization referrals, independence, and physical exercise for the elderly was limited. The cadres' skills in filling out health evaluation charts, assessing mental, emotional, and nutritional status, measuring blood pressure, and instructing physical exercise were also inadequate. There was a significant difference in the knowledge and skills of the health cadres before and after training (p<0.05). In conclusion, there was an improvement in the health cadres' knowledge and skills regarding comprehensive health services for the elderly at the Posyandu Lansia.
Workload Indicators of Staffing Need (WISN) for the Required Estimation of Nursing Staff in a Hemodialysis Unit
Authors: Feli Clarisa Winvi  , Sri Lestari Ramadhani Nasution  , Chrismis Novalinda Ginting
Published: September 2023

Highlights:

This article presents an understudied topic of nursing workloads in a hemodialysis unit and concludes that directly and indirectly productive activities occupied the majority of the nurses' working time. 
An analysis using the Workload Indicators of Staffing Need produced a general report that may prompt re-evaluation of nursing staff requirements and policy-making for workload distribution. 

Abstract
The number of hemodialysis patients continues to increase almost every month, while the number of nurses in the Hemodialysis Unit at Rasyida Renal Specialist Hospital, Medan, Indonesia, remains constant. This situation has increased the nurses' workload and responsibilities. Therefore, it is necessary to examine the balance between the workload and the number of required nursing staff in the Hemodialysis Unit at Rasyida Renal Specialist Hospital. This study aimed to identify the optimal number of nursing staff required in the Hemodialysis Unit at the hospital in 2022. This study used a mixed-methods approach using the Workload Indicators of Staffing Need (WISN) method. This study included 44 nurses working in the Hemodialysis Unit at Rasyida Renal Specialist Hospital. Primary data included questionnaires, observations, and interviews during working hours, while secondary data included document reviews and staffing data. WISN calculations showed that the Hemodialysis Unit required a total of 65 nursing staff. In other words, an addition of 21 nursing staff was needed to meet the current workload. In conclusion, the current human resources available are not sufficient, and the workload is beyond the capacity of the nursing staff at the hospital.
Treatment of Acute Diarrhea in Children Aged 1–5 Years Provided by Doctors in Surabaya
Authors: Alpha Fardah Athiyyah  , Insyira Rayhana Irsan  , Nurmawati Fatimah
Published: September 2023

Highlights:
1. The focus of this study was on the treatment methods for acute diarrhea, which have not been extensively investigated in the region studied.2. This study can provide an overview of doctors' adherence to the available guidelines for the treatment of acute diarrhea in children aged 1–5 years in Surabaya, Indonesia.
Abstract:
Diarrhea is the second leading cause of death among children under five, following pneumonia. Insufficient knowledge of diarrhea and dehydration management may contribute to this high mortality rate. Implementing prompt and effective management and prevention strategies has the potential to decrease morbidity and mortality associated with diarrhea. Therefore, this cross-sectional study aimed to investigate the treatment methods used by doctors for children aged 1–5 suffering from acute diarrhea in Surabaya, Indonesia. Data were collected from doctors in Surabaya using an online form containing case-based questions. Microsoft Excel for Mac version 16.17 (Microsoft Inc., Redmont, WA, USA) was used to process the binary data by calculating frequencies and percentages with a point estimate of 95% confidence interval (CI). A descriptive method was used in the data analysis, and the findings were presented in tables. From a total of 51 respondents who participated in this study, 18 (35.29%) only administered oral rehydration therapy. In addition, 49 respondents (96.08%) prescribed zinc supplementation for ten days, while 10 respondents (19.61%) opted for antibiotics. Interestingly, 49 respondents (96.08%) recommended both breast milk and food for the patients, and nearly all respondents provided guidance to the mother or caregiver of the patient. The findings of this study suggested that the respondents primarily used rehydration therapy to treat children suffering from acute diarrhea with moderate dehydration. However, some respondents still relied on antibiotics despite the available recommendations to use oral rehydration therapy. Nearly all respondents agreed on zinc supplementation, breast milk and food provision, and advice for the mother or caregiver of the patient. While certain aspects of the disease management for diarrhea align with the recommended guidelines, there is room for improvement in promoting the exclusive use of oral rehydration therapy and reducing unnecessary antibiotic prescriptions.
Effect of industrial digitalization on total halal meat production in Java
Authors: Riduwan Riduwan , Wardhana Akhmad Kusuma
Published: September 2023

The demand for halal meat in Indonesia is very large. Java Island is an area with a large production of halal meat in Indonesia. This study aims to analyze the effect of the number of digital equipment, Human Development Index levels, and digital payment modes on the productivity level of halal meat in the three largest provinces on the island of Java. This study uses panel data on the number of digital device usage, Human Development Index, number of digital payments, and total production of halal meat in East Java, West Java, and Central Java in 2015-2022. Data were analyzed using Eviews 10 software. The results show that digital devices used in the halal meat industry do not necessarily affect halal meat production in the provinces of East Java, Central Java, and West Java. However, HDI and the number of digital payments have a positive effect on halal meat production in the provinces of East Java, Central Java
Detection of porcine species DNA on meat processed food samples (shredded meat) using Real-Time PCR
Authors: Sophian Alfi , Utaminingsih Sri , Bhakti Tirta Setya , Rahmawati Dewi
Published: September 2023

DNA detection of porcine species in processed meat samples (shredded meat) was carried out as an effort to enrich the literature and reference alternative testing methods in the control of halal products circulating in Indonesia. The purpose of this study was to detect the DNA of porcine species in samples using real-time PCR. The research method used is a qualitative technique. This technique analyzes the CT value of the sample compared to the positive control by looking at the formation of the sigmoid curve if amplification occurs. The controls used consisted of negative control, positive control, other DNA control, and LOD control. The extraction technique used is the column centrifuge technique. The extraction results were then measured using a nano photometer to see the purity and concentration of the extracted DNA. Based on the research, it is known that the extraction results read on a nanophotometer at a wavelength of A260 / A280 show a concentration of 24,350 with a purity value of 21,164. For sample testing, the results of real-time PCR analysis showed the sample was detected at CT 39.77, positive control at CT 31.66, and LOD at 28.32. for negative control and specificity using other DNA was not detected. The conclusion of this research is that the sample used can be detected by the presence of porcine DNA.
Globalization of Culture and Identity: Case Study of Halal Tourism Thailand as a Muslim Friendly Tourist Destination
Authors: Anggara Wahyu Pratama Nur
Published: September 2023

Globalization has consequences for the survival of culture. In this discussion, the authors emphasize the study of hybridization as a perspective in seeing the impact of globalization on culture. This can be shown through a case study of Thailand as 'The Kitchen of The World'. Thailand is one of the leading halal food producers, both regionally and internationally. This description emphasizes the author's stance that globalization has contributed to the cultural hybridization of the global halal trend with the identity of the Thai Buddhist population as a Muslim-friendly tourist destination country through halal tourism. Globalization has an influence on the development of an increasingly heterogeneous culture. The spiritual dimension or halal religious values as a foreign culture can also blend with the social conditions of Thai society. Through this explanation, briefly, it is obtained that first, globalization encourages the influence of cultural hybridization through the share of global migrants or in this case Muslim tourists. Both halal are seen as a lifestyle choice instead of emphasizing spirituality or religion reflecting the cosmopolitan sharia. Finally, the development of global culture is aligned with the global economy or halal as a commodity, and on the other hand, Thailand takes the position of being a Muslim-friendly country due to massive global migration as a result of rapid globalization.
 
Keyword: Thailand, Halal Tourism, Globalization, Hybridization
Optimization of Deoxyribonucleic Acid (DNA) isolation methods from several types of cosmetic samples for molecular-based halal tests
Authors: Nafisa Arini  , Afifatul Achyar
Published: September 2023

Bagi seorang muslim status halal suatu produk pangan maupun non-pangan harus terpenuhi secara mutlak, begitu juga dengan produk kosmetik. Kosmetik terdiri dari berbagai bahan dan yang menjadi titik kritis status kehalalan suatu produk kosmetik adalah kompleksitas komposisi produk kosmetik yang memungkinkan penggunaan bahan dasar yang berasal dari babi seperti  gelatin, asam lemak, gliserin dan kolagen yang mana bahan-bahan tersebut adalah bahan yang sangat umum digunakan dalam pembuatan produk kosmetik. Tujuan dilakukannya penelitian ini adalah untuk untuk mengoptimasi metode isolasi DNA pada beberapa jenis sampel kosmetik untuk uji halal berbasis molekuler. Penelitian dilakukan dalam tiga tahap, yaitu ekstraksi DNA, amplifikasi dan analisis rt-PCR, dan tahap terakhir adalah visualisasi dengan media elektroforesis gel agarose. Optimasi isolasi DNA dilakukan dengan tiga metode yang berbeda, yaitu dengan menggunakan kit isolasi DNA QIAamp® DNA Mini Kit (QIAGEN), isolasi dengan laruta phenol-chlororoform GENEzol™ (Geneaid), dan menggunakan campuran resin Chelex-TE 10%. Hasil menunjukkan bahwa metode isolasi terbaik dari ketiga metode yang dilakukan adalah metode isolasi DNA dengan menggunakan QIAamp® DNA Mini Kit (QIAGEN) yang mana berdasarkan visualisasi elektroforesis metode ini dapat mengisolasi DNA dari semua sampel.
Analysis of consumers’ self-congruity through halal fashion brand personality
Authors: Ali Dini Salmiyah , Matanra Athaya Kamila
Published: September 2023

The halal industry in Indonesia is developing brilliantly, including in halal fashion. Behind the great potential and desire to become the mecca of world Muslim fashion, there is intense competition between fashion brands and consumers who tend to be critical in making their choices.  Facing this new reality, a company in this industry must ensure that it can maintain its existence in the long term by creating its product identity (brand personality) and understanding consumer behavior that tends to direct choices to brands they feel are close or suitable to itself, including PT Soka Cipta Niaga (SOKA) as a company that produced the first halal socks. The purpose of this study is to examine how the suitability of consumers' self-image through the personality of a halal fashion brand. This study uses a qualitative approach with descriptive research and data collection techniques conducted through in-depth interviews with Focus Group Discussions (FGD), observation, and documentation of SOKA consumers.  The results of the study show that there are only three dimensions of the personality of the halal brand that is most prominent from the SOKA brand, namely excitement, purity, and righteousness personality.  Among these three personalities, righteousness then becomes the only halal brand personality that is most congruence with the actual and ideal self-image of its consumers, which can help to show and satisfy their self-concept needs for religious obedience and adherence in using products that are considered relevant to sharia principles.
I Don’t Want to Think About It!: A Qualitative Study of Hypertensive Women’s Awareness and Perception of Heart Disease
Authors: Sutantri  , Nina Dwi Lestari  , Resti Yulianti Sutrisno  , Laili Indah Wulandari  , Riska Putri Rachmawati
Published: September 2023

Background: Research has shown an increasing number of young women between the ages 35 and 54 having heart attacks. However, data demonstrated a persisting failure to raise women’s awareness of cardiovascular disease risk. Moreover, very little has been done to date in low- and middle-income countries to educate women on cardiovascular disease risks and the high mortality rates for women. Aims: The aim of this study was to explore hypertensive women’s awareness and perceptions of heart disease. Methods: A qualitative research design using semi-structured interviews was performed. Data were analyzed using an inductive thematic analysis approach. Results: In total, 25 women participated in this study. Three main themes emerged: (1) perception of heart disease and its risk factors, (2) ‘I don’t want to think about it’: perspectives on future risk, and (3) strategies to prevent heart disease. From the participants’ narratives, it was evident that the women in this study had limited knowledge related to heart disease. Although all participants suffered from hypertension, the women still underestimated their risk of developing heart disease in the future. Many women believed that praying to God and maintaining an optimistic mindset could protect them from heart disease. Conclusion: The study’s findings highlight a clear indication of the need to implement renewed strategies for educating women about cardiovascular health tailored to target the rural populations in Indonesia. Raising women's awareness might reduce their risk of suffering from cardiovascular disease in the future.
Theory of Planned Behavior: Intention to Quit Smoking at Universitas Negeri Malang during Pandemic Covid-19
Authors: Windi Chusniah Rachmawati  , Yunita Anis , Endang Sri Redjeki
Published: September 2023

Background: Smoking has become a lifestyle. Smokers are dominated by teenagers, including college students. Smoke from cigarettes clearly poses a danger to the body's health and the environment, especially during the COVID-19 pandemic. During the pandemic, college students spend more time at home which can increase smoking behavior too. Aims: The purpose of this study is to analyze the description of the intention to quit smoking at the State University of Malang during COVID-19 based on the Theory of Planned Behavior (TPB). Methods: This research is a type of quantitative analysis using primary data. The instrument used is a questionnaire which is filled out independently by the respondent. Data collection was done online for 100 students of the State University of Malang. The statistical test used in the analysis is the Chi-square test and Regression Logistic. Results: Variables related to the intention to quit smoking were attitude (sig=0.03 < α=0.05) and behavioral control (sig=0.00 < α=0.05), while the subjective norm variable had no relationship with intention, quit smoking (sig=0.077 > α=0.05). Behavioral control has a significant effect on the intention to stop smoking (sig = 0.00 > α=0.05). Conclusion: There is a relationship between attitude and behavioral control with students' intention to quit smoking. Only behavioral control affects the intention to quit smoking, so it is necessary to strengthen this variable to increase the intention of students at the State University of Malang to quit smoking and as an effort at tobacco control among adolescents.
Cavendish Banana Peel Extract’s Antibacterial Activities Potential as Disinfectant
Authors: Ramadhan Erlangga Lazuardi , Retnowati Wiwin , Dewanti Linda , Wahyunitisari Manik Retno
Published: September 2023

Highlights:1. The COVID-19 pandemic makes personal hygiene more important than ever, and antibacterial substances such as disinfectants are crucial in maintaining said hygiene.2. The MBC of cavendish banana peel extract against the growth of bacteria Escherichia coli and Staphylococcus aureus was 25%, with no activity against Bacillus subtilis.3. Musa acuminata peel extract has the potential to be used as a disinfectant.
AbstractIntroduction: The COVID-19 pandemic makes personal hygiene more important than ever, and antibacterial substances such as disinfectants are crucial in maintaining said hygiene. This study aimed to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of cavendish banana peel extract (Musa acuminata) against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis.    Methods: The design of this study was a laboratory experiment that used the broth dilution method with test tubes using methanol as the extract’s solvent. Sterile aquadest was used as the solvent, and Mueller-Hinton broth was used as the growth medium in tubes. All samples of the bacteria (Staphylococcus aureus, Escherichia coli, and Bacillus subtilis) were provided by the Laboratory of Microbiology Faculty of Medicine, Universitas Airlangga.Results: MBC was the only parameter found due to the color and particulates, which hindered the turbidity assessment of MIC. From the dilution test, the MBC of cavendish banana peel extract against the growth of bacteria Escherichia coli and Staphylococcus aureus was 25%, with no activity against Bacillus subtilis.Conclusion: There were antibacterial activities of Musa acuminata peel extract against Staphylococcus aureus and Escherichia coli. Therefore, it has the potential to be used as a disinfectant.
The Effectiveness of Meloxicam Adjuvant Therapy against Negative Symptoms and Neutrophil Lymphocyte Ratio (NLR) in Schizophrenic Patients
Authors: Melati Katarina Bernadet Dinda Sekar , Hardaetha Adriesti , Kusuma Wijaya
Published: September 2023

Highlights:1. The NLR value can show the role of neuroinflammation in schizophrenic patients.2. Meloxicam as adjuvant therapy can improve negative symptoms and changes in the NLR in schizophrenic patients.
AbstractIntroduction: Neutrophil-lymphocyte ratio is a simple and affordable marker of inflammation that has recently been widely used to assess systemic inflammation in psychiatric patients. This study aimed to determine and analyze the effectiveness of meloxicam as adjuvant therapy to improve negative symptoms and changes in the neutrophil-lymphocyte ratio (NLR) in schizophrenic patients. Methods: This was a quasi-experimental study using a single-blind, pretest–post-test design. Subjects were determined using a purposive sampling technique based on inclusion criteria. This study examined 34 samples and divided them into two groups. The treatment group consisted of 17 subjects who received adjuvant therapy with meloxicam 15 mg/day for 4 weeks and 17 subjects in the control group. Data collection was obtained from medical records, interviews, field notes, positive scale, negative scale, and general psychopathology scale (PANSS) assessment sheets, and blood NLR examinations. Data analysis used SPSS 25.0.Results: The negative subscale PANSS score in the treatment group decreased lower than in the control group, with p-value = 0.640. However, the decrease in NLR values was more significant in the treatment group than in the control group, with p-value = 0.094. There was a decrease in the negative subscale PANSS scores and clinical NLR scores, but it was not statistically significant.Conclusion: Adjuvant therapy with Meloxicam, given once a day for four weeks, had an effect on decreasing the negative subscale PANSS score and NLR scores for schizophrenic patients at Dr. Arif Zainudin Regional Mental Hospital (RSJD), Surakarta, clinically, but it was not statistically significant.
The Differences in Adjuvant Therapy Effectiveness Meloxicam and N-Acetylcysteine against Negative Symptoms of Schizophrenia
Authors: Murda Banu Kadgada Kalingga , Nugroho I Gusti Bagus Indro , Herdaetha Adriesti
Published: September 2023

Highlights:1. Schizophrenic patients can have negative symptoms.2. Adjuvant therapy is needed to assist antipsychotics in reducing the negative symptoms of schizophrenic patients.
AbstractIntroduction: Meloxicam and N-Acetylcysteine are examples of drugs with anti-inflammatory effects that have been widely studied, and are considered to reduce negative symptoms of schizophrenia. Both of these drugs are also widely available in Indonesia and can be obtained at an affordable price. This study aimed to analyze the differences in the effectiveness of adjuvant therapy meloxicam and N-Acetylcysteine on negative symptoms of schizophrenic patients. Methods: This was a quasi-experimental study using a single-blind, pretest–post-test design. Determination of the subject used a purposive sampling technique according to the inclusion criteria. This study examined 34 samples and divided them into two groups. In group A, 17 subjects received adjuvant meloxicam therapy of 15 mg/day for 4 weeks; in group B, 17 subjects received adjuvant therapy of N-Acetylcysteine 400 mg/day for 4 weeks. Score assessment was performed using the positive scale, negative scale, and general psychopathology scale (PANSS) negative subscale pre- and post-therapy, then compared the effectiveness. Data analysis used SPSS 25.0.Results: The mean score of the PANSS post-test subscale was negative in the meloxicam adjuvant therapy group 15.58, while for the N-Acetylcysteine adjuvant therapy group was 17.64 with a p-value of 0.009. The mean decrease in the negative subscale PANSS score in the meloxicam adjuvant therapy group was 11.00, while the N-Acetylcysteine adjuvant therapy group was 19.70 with a p-value of 0.000.Conclusion: There was no difference in the effectiveness of adjuvant therapy meloxicam and N-Acetylcysteine in improving negative symptoms of schizophrenic patients.
Internationalization Of Small And Medium Enterprises In Indonesia: Towards Integrative Policy Approach Of Competitiveness And Connectivity
Authors: Junita Fifi , Yuniarti Yuniarti , Innayatun Soeparna Intan , Resistensia Kesumawardhani
Published: September 2023

The paper focuses on the policy analysis influencing the internationalization of small and medium sized enterprises (SMEs) engaged in cultural and creative industries (CCIs) in Indonesia. Three approaches of internationalization are explored in this study: the market knowledge approach, the network approach and the international entrepreneurship approach. This article attempts to figure out internationalization as a process starting from the creating of favorable preconditions to the strengthening stage based on the interrelationship among those approaches. The purpose of this article tries to combine the important dimensions proposed by each approach towards an integrative policy approach based on the concept of competitiveness and connectivity. The conceptual model of integrated policy in this study contributes to resolve inefficiency issue as the main gap in the existing strategic policy on SME internationalization in Indonesia; enhance integrative policy analysis literature and propose a more integrated strategic policy for promoting internationalization.
Regulating Court Jurisdiction to Protect Weaker Parties: An Overview of the Indonesian Civil Justice System
Authors: Sujayadi Sujayadi , Wijayanta Tata , Herliana
Published: September 2023

It is necessary to facilitate an easy access to the courts to protect weaker parties. This can be achieved by regulating the personal jurisdiction of the court, so that weaker parties can easily access the courts. In Indonesian civil justice system, some regulations have been implemented to protect weaker parties through the jurisdiction of the courts. This article will elaborate those regulations and their obstacles in protecting the access of consumers, workers, women and children, and foreigners to the Indonesian courts. Statutory approach with reference to the general principles of the court personal jurisdiction and the principles of access to justice for the weaker parties will be employed. This article finds that some regulations related to the court personal jurisdiction in Indonesia provide protection to the weaker parties by allowing them to submit their claim to the court where they reside against the counterparty. However, lack of consistency may hinder the implementation.
Limitation of Misconduct of Judges: Increasing The Synergy of Supervision of Judges by The Judicial Commission and The Supreme Court
Authors: Hamdan Fairuz Zahirah Zihni , Kristianti Dwi Rahayu , Vincentius Verdian
Published: September 2023

The supervision of judges in judicial power in Indonesia is carried out by two state institutions: the Judicial Commission and the Supreme Court. Internal supervision of judges is carried out by the Supreme Court on the judicial technicalities of judges and externally by the Judicial Commission on the ethical aspects of judge behavior. However, in its implementation, there is still no explicit limit to the scope of judges’supervision between the two institutions. This research aims to provide a different perspective and new breakthrough in judge supervision, namely, setting a boundary between judicial technical violations and ethical violations in examining alleged ethical violations by judges as a form of judicial supervision. The type of research used was reform-oriented research using a statutory and conceptual approach. The results showed that the mechanism for supervising judges was regulated through the Joint Regulations of the Supreme Court and Judicial Commission on the Code of Ethics and Code of Conduct for Judges (KEPPH), KEPPH Enforcement Guidelines, and Joint Examination Procedures. However, in its implementation, there is still a problem of unclear scope and limitations in the supervision of judges. Therefore, there must be improvements in related regulations by limiting technical judicial violations and ethical behavior.
Digitalisation and IT Strategy in the Hospitality Industry
Authors: Wynn Martin , Lam Carmen
Published: September 2023

This article explores how digitalisation is impacting the hospitality industry and assesses the evolving role of Information Technology (IT) strategy in the digitalisation process. The research approach is qualitative and inductive, based on six in-depth interviews with senior IT professionals in the hospitality industry. Findings indicate significant differences in the role of IT strategy in guiding digitalisation in the companies studied. The depth of information provided by the interviewees supports the development and application of a model that profiles the companies regarding their degree of digitalisation and technology integration. Analysis of interview material allows the identification of key properties for successful digitalization: process agility, workforce adaptability, and technology manageability, along with a clear data culture and ensured cybersecurity. However, disparate systems and technologies, and a lack of data integrity, are key issues that leave hospitality companies with difficult choices in progressing digitalisation initiatives. The applied model and identification of key properties for successful digitalisation contribute to the development of related theory and can also be used as a reference point for senior IT professionals working in the industry.
Reality Dosen't Shine, It Twinkles
Authors: Sulis William
Published: September 2023

Arguments have been made that violation of the CHSH and similar inequalities shows that reality at the quantum level must be non-local. The derivation of Bell inequality is re-examined and it is shown that violations of these inequalities merely demonstrates the existence of contextuality - they say nothing about the causal influences underlying such contextuality. It is argued that contextual systems do not possess enduring (propositional) properties, merely contingent properties. An example is presented of a classical situation, a two player co-operative game, whose random variables are consistently connected in the sense of Dzhafarov, and which is contextual, violating the CHSH inequality. In fact it also violates the Tsierl'son bound. The key is that this system is generated and its properties are disposed, not determined.
Fipronil Degradation in Soil by Enterobacter chengduensis Strain G2.8: Metabolic Perspective
Authors: Prado Caio , Pereira Rodrigo , Durrant Lucia , Júnior Rômulo , Piubeli Francine , Bonfá Maricy
Published: September 2023

Fipronil is an insecticide widely used in the agricultural and veterinary sectors for its efficacy in pest control. The presence of fipronil in the environment is mainly due to agricultural and domestic practices and is frequently found in different types of environmental matrices in concentrations ranging from µg/L to mg/L and can be hazardous to non-target organisms due to its high toxicity. This study was carried out to obtain and characterize microorganisms from soil which are capable of biodegrading fipronil that could be of great biotechnological interest. For this purpose, a bioprospecting was carried out using fipronil (0.6 g/L) as the main source of carbon and nitrogen for growth. Once obtained, the strain was identified by sequencing the 16S ribosomal RNA (rRNA) gene and the capacity to degrade fipronil was monitored by GC-MS. Our study showed the presence in soil samples of the strain identified as Enterobacter chengduensis, which was able to metabolize fipronil and its metabolites during the mineralization process. Enterobacter chengduensis was able to biodegrade fipronil (96%) and its metabolites fipronil-sulfone (92%) and fipronil-sulfide (79%) in 14 days. Overall, the results of this study provided a bacterium with great potential that could contribute to the degradation of fipronil in the environment.
Design, Synthesis, and Evaluation of Novel Indole Hybrid Chalcones and Their Anticancer and Antioxidant Activity
Authors: Kudličková Zuzana , Michalková Radka , Salayová Aneta , Ksiažek Marián , Vilková Mária , Bekešová Slávka , Mojžiš Ján
Published: September 2023

The synthesis, anticancer and antioxidant activity of a series of indole-derived hybrid chalcones are reported here. First, using well known Claisen-Schmidt condensation method a set of 29 chalcones has been designed, synthesized, and consequently characterized. Subsequently, screening for the antiproliferative activity of the synthesized hybrid chalcones was performed on the on five cancer (HCT116, HeLa, Jurkat, MDA-MB-231 and MCF7) and two non-cancer (MCF-10A and Bj-5ta) cell lines. Chalcone 18c bearing 1-methoxyindole and catechol structural features, exhibited selective activity against cancer cell lines with IC50 values of 8.0 ± 1.4 µM (Jurkat) and 18.2 ± 2.9 µM (HCT116) and showed no toxicity to non-cancer cells. Furthermore, antioxidant activity was evaluated using tree different methods. The in vitro studies of radical scavenging activity utilizing DPPH radicals, as well as FRAP method, demonstrated the strong activity of catechol derivatives 18a-c. According to the ABTS radical scavenging assay, the 3-methoxy-4-hydroxy substituted chalcones 19a–c were slightly more favorable. In general, a series of 3,4-dihydroxychalcone derivatives showed properties as a lead compound for both antioxidant and anticancer activity.
Neural Network Structure for Tracking the Climate Temperature Change
Authors: Topalova Irina Hristova , Radoyska Pavlinka Goranova
Published: September 2023

Tracking temperature changes in certain geographic regions is a current task in modern research on Earth's climate changes. One of the global problems in solving this task is related to the large volume of measured data and the search for appropriate methods for effective determination of changes. The purpose of this research is to track climate temperature changes using a machine learning-based automated change detection method. The presented method includes training of a two-level structure of neural networks, with measured temperatures for a ten-year period of time for a certain geographical region. In the testing phase, the neural structure classifies measured temperatures for two three-year periods, before and after the ten-year time period, respectively, for the same geographic region. An algorithm was developed to visualize the studied regions by creating a map with their geographic coordinates. The classification results in the neural structure outputs are presented and analyzed as possible temperature changes. Suggestions for continuing and expanding the research in the future are discussed.
Magnetic and Geochemical Properties of Zagreb City Area Soils
Authors: Frančišković-Bilinski Stanislav , Peco Josip , Sakan Sanja , Đorđević Dragana , Inđić Dejan
Published: September 2023

The study was performed to get the first insight of distribution of the low field volume magnetic susceptibility (MS) throughout the Zagreb city area, based on in-situ field measurements. Most interesting locations were selected for soil sampling and geochemical content was determined using ICP-OES. A geostatistical approach was applied on MS and geochemical results. Median value of 0.245 x 10-3 SI units is proposed to be used as relevant average MS value in Zagreb area. Mean concentrations of heavy metals in Zagreb soils (in µg/g) are: Pb (36.82), Zn (87.77), Cu (30.84), Cd (0.66), Cr (29.04), Co (11.89) and Ni (28.40), being relatively low in comparison with Croatian legislation and with European and world average. Boxplot analyses showed that 45% of studied elements do not show any anomaly, while the rest of elements mostly show only one weak anomaly and they are located at the same sites as MS anomalies. Statistical analysis found significant correlations between MS and following elements: Cd, Co, Fe, Mn, Na, Pb, Sb and Zn. In-situ MS measurements proved to be an efficient tool for initial screening of large areas in terms of elevated heavy elements concentrations, enabling cheap and fast assessment of state of environment.
Plasmid-Mediated Genes Were Responsible for the Resistance and Spread of Metallo Beta-Lactamase (MBL)-Producing Pseudomonas Aeruginosa Isolates in Poultry Milieus
Authors: Ejikeugwu Chika , Duru Carissa , Onu Euslar , Nwakaeze Emmanuel , Adonu Cyril , Okorie Ndidiamaka , Ujam Nonye , Ebenebe Ijeoma , Mba Theodora , Mba Anthonia , Ezeador Chika , Edeh Chijioke , Ugwu Malachy , Adikwu Michael
Published: September 2023

Bacterial resistance to antibiotics is a public health menace that needs urgent efforts to mitigate and forestall their transmission in the general environment. Plasmid-mediated metallo beta-lactamase (MBL) gives bacteria an exceptional ability to transmit resistance genes. This study investigated plasmid-mediated resistance in MBL P. aeruginosa isolates from poultry food chain settings. Cloacal swab samples (n=120) were bacteriologically analyzed for the isolation of P. aeruginosa isolates. Susceptibility studies were performed by the CLSI guideline using selected antibiotics. MBL was phenotypically detected using modified Hodges test, and confirmed using PCR technique. Plasmid curing studies detected the presence of plasmids in the isolates. P. aeruginosa isolates (n=48) showed high levels of reduced susceptibility to cefoxitin (93.8%), imipenem (81.3%), gentamicin (85.4%), amikacin (85.4%), nitrofurantoin (83.3%), ofloxacin (72.9%) and cefotaxime (77.1%). MBL was phenotypically detected in 7 (14%) isolates of P. aeruginosa. The presence of blaIMP-1 and blaIMP-2 MBL genes in P. aeruginosa (n=5) isolates was confirmed by PCR. The PCR did not detect blaVIM-1 and blaVIM-2 MBL genes. The P. aeruginosa isolates were multidrug resistant, with about 50% of the isolates showing multidrug resistance (MDR) to the antibiotics. The genes for MDR in the P. aeruginosa isolates were borne on plasmids, indicating a high possibility of community transmission of MBL resistance genes. Finally, the P. aeruginosa isolates from poultry food chain milieus are multidrug resistant, produce MBL, and harbour their resistance genes on plasmids. Since many antibiotic resistance genes in bacteria are associated with mobile genetic elements (MGEs) like plasmids, it is important to step up actions to mitigate incessant use of antibiotics in poultry and other agricultural practices in Nigeria in order to diminish the evolution and spread of plasmid-mediated resistance which is capable of initiating community acquired infections that may prove difficult to treat in our hospitals with the available antibiotics.
A Business Strategy Framework for Patent Pooling in the Solar Cell Supply Chain
Authors: Lee Shuo-Min , Chen Jen Shyang , Chang Chi-Cheng
Published: September 2023

The solar cell industry is a part of the green energy sector, and effectively combining the patents of various manufacturers within the supply chain to collectively create sustainable patent market value is of paramount importance. This study aimed to establish a business strategy framework for Project-based licensing through the analysis of solar cell patents and the integration of supply chain manufacturers' patents, with the goal of collectively creating market value for patents sustainably. The research methodology included literature analysis and focus group discussions. Initially, the study analyzed solar cell industry patents from the past decade using the WIPS Global Patent database to identify projects with the highest patent count. Subsequently, through the use of focus group discussions, the feasibility of a patent pool strategy within the supply chain was explored. Finally, a strategy framework was proposed for Project-based patent pool licensing, focusing on the top 15 projects with the highest count of 5,579 patents. The results indicated that adopting this strategy framework for supply chain manufacturer patents can result in higher commercial patent value.