bluuebunny/crossref_metadata_2025 huggingface dataset:
Laparoscopically resected perivascular epithelioid cell tumor of the ascending colon demonstrating submucosal tumor morphology: a case report
Authors: Nagai Yuzo , Kiyomatsu Tomomichi , Kume Ayako , Kataoka Atsuko , Gohda Yoshimasa , Otani Kensuke , Deguchi Katsuya
Published: August 2020

Background: The differential diagnosis for a colonic submucosal tumor (SMT) can include many types of cancer. We report a case of a perivascular epithelioid cell tumor (PEComa), a rare mesenchymal neoplasm that demonstrates SMT morphology, in the ascending colon.Case presentation: A mass was incidentally detected by computed tomography (CT) in a 53-year-old man. Colonoscopy revealed an SMT with central ulceration in the ascending colon, and 18F-fluoro-2-deoxy-D-glucose positron emission tomography CT demonstrated a high maximum standardized uptake value of 7.33. Preoperative diagnosis was inconclusive. Given the malignant potential of the tumor, we performed a laparoscopic right hemicolectomy with D3 lymph node dissection. The tumor was 5.5 cm × 4.1 cm and located in the submucosa and muscular propria. There was no lymph node metastasis (0/46). Based on the positive immunohistochemical stainings of both melanocytic (HMB45) and muscle (desmin) markers, we diagnosed the tumor as a PEComa. In the 17 months since surgical resection, the patient has not experienced recurrence, but careful observation should continue because of the malignant potential of the tumor.Conclusions: Although rare, a PEComa should be considered in the differential diagnosis of colonic SMT. Immunohistochemical staining of melanocytic and muscle markers is useful for the diagnosis.
Susceptibility to Malaria During the Prevention of Re-introduction/Re-establishment Phase in Sri Lanka
Authors: Jeevatharan Hamsananthy , AR Wickremasinghe
Published: August 2020

BackgroundSusceptibility to malaria is the predisposition of populations to be infected by malaria parasites. It is influenced by the age-sex composition, parasitaemia, immunity, pregnancy status, type of residency, socio economic status, history migration of the population; broadly biological and generic factors. As imported cases are still being reported and one introduced malaria case was reported in 2018, prevention of re-introduction/re-establishment of malaria is a challenge for Sri Lanka. Addressing susceptibility to malaria is crucial for planning and implementing appropriate interventions to sustain malaria-free status of the country. The aim of this study was to assess susceptibility to malaria during the prevention of re-introduction/re-establishment phase in Sri Lanka. Methods A national survey was conducted among 3,454 households. A multistage cluster sampling technique was used to select the households. Susceptibility was assessed based on a developed conceptual framework adapted from Kienberger and Hagenlocher (2014), and an interviewer-administered questionnaire. Data analysis was done using SPSS version 20 package. ResultsThere was zero prevalence of malaria parasites both in the general population and among fever patients. The proportion of population who had been overseas within the last 3 years in the urban sector (4.5%, n=99) was significantly higher than that of rural (2.8%, n=288) and estate sectors (0.2%, n=2) (χ42=66.103; p<0.001) and it significantly declined with the wealth index up to the 4thquintile with a slight rise in the 5th quintile (χ82=60.985; P<0.001).Conclusions Zero prevalence of malaria parasites supports the malaria-free status of the country and pooled blood samples may be tested during reactive case surveillance as a cost-effective approach. Urban and upper socioeconomic class population should be targeted for screening and awareness programmes on prevention of re-establishment of malaria.As susceptibility is a dynamic phenomenon, its assessment should be done periodically. Combining it with the resilience and receptivity, social vulnerability and risk of re-introduction/re-establishment of malaria could be assessed.
Liver Resection for Colorectal Liver-limited Metastases in Elderly Patients: A Propensity Score Matching Analysis
Authors: Jin Ke-Min , Wang Kun , Bao Quan , Wang Hong-Wei , Xing Bao-Cai
Published: August 2020

Background: Few studies have focused on the role of hepatectomy for colorectal liver-limited metastases in elderly patients compared to matched younger patients.Methods: From January 2000 to December 2018, 724 patients underwent hepatectomy for colorectal liver-limited metastases. Based on a 1:2 propensity score matching (PSM) model, 64 elderly patients (≥ 70 years of age) were matched to 128 younger patients (༜70 years of age) to obtain two balanced groups with regards to demographic, therapeutic and prognostic factors.Results: There were 73 elderly and 651 younger patients in the unmatched cohort. Compared with the younger group (YG), the elderly group (EG) had significantly higher proportion of American Society of Anesthesiologists score Ⅲ and comorbidities, and lower proportion of more than 3 liver metastases and postoperative chemotherapy (p < 0.05). After PSM for these factors, rat sarcoma virus proto-oncogene/B-Raf proto-oncogene (RAS/BRAF) mutation status and primary tumor sidedness, the EG had significantly less median intraoperative blood loss than the YG (175 ml vs. 200 ml, p = 0.046), a shorter median postoperative hospital stay (8 days vs. 11 days, p = 0.020) and a higher readmission rate (4.7% vs.0%, p = 0.036). The EG also had longer disease-free survival (DFS), overall survival (OS) and cancer-specific survival (CSS) compared to the YG, but these findings were not statistically significant (p > 0.05). Old age was not an independent factor for DFS, OS and CSS by Cox multivariate regression analysis (p > 0.05).Conclusions: Hepatectomy is safe for colorectal liver-limited metastases in elderly patients, and these patients may subsequently benefit from prolonged DFS, OS and CSS.
Novel Oxidative Stress-related Prognostic Biomarkers for Melanoma Associated With Tumor Metastasis
Authors: Wu Xianpei , Wu Zhengyuan , Zhao Jinmin
Published: August 2020

Background
Skin cutaneous melanoma (SKCM) is a prevalent skin cancer whose metastatic form is dangerous due to its high morbidity and mortality. Previous studies have systematically established the vital role of oxidative stress (OS) in melanoma progression. This study aimed to identify prognostic OS genes closely associated with SKCM and illustrate their potential mechanisms.
Methods
Transcriptome data and corresponding clinical traits of patients with SKCM were retrieved from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. A weighted gene co-expression network analysis was conducted to identify relationships between clinical features and OS genes in specific modules. Subsequently, Cox regression analysis was performed on candidate OS genes; four hub prognosis-associated OS genes (AKAP9, VPS13C, ACSL4, and HMOX2) were identified to construct a prognostic model.
Results
After a series of bioinformatics analysis, our prognostic model was identified significantly associated with the overall survival of patients with SKCM and metastatic ability of the cancer. Furthermore, our risk model demonstrated improved diagnostic accuracy in TCGA and GEO cohorts. In addition, we established two nomograms based on either risk score or hub genes, which displayed favorable discriminating ability for SKCM.
Conclusions
Together, our results provide novel insight into the potential applications of OS-associated genes in SKCM.
Polypharmacy Among Older Brazilians: Prevalence, Factors Associated and Sociodemographic Disparities (ELSI-Brazil)
Authors: Seixas Brayan Viegas , Freitas Gabriel R. M.
Published: August 2020

The authors have requested that this preprint be removed from Research Square.
Clinical Impact of Intratumoral EpCAM-Positive Cancer Stem Cell Heterogeneity in Patients with Hepatocellular Carcinoma
Authors: Krause Jenny , von Felden Johann , Casar Christian , Fründt Thorben W. , Galaski Johanna , Schmidt Constantin , Jung Caroline , Ittrich Harald , Weidemann Sören Alexander , Krech Till , Heumann Asmus , Li Jun , Fischer Lutz , Sauter Guido , Lohse Ansgar W. , Wege Henning , Schulze Kornelius
Published: August 2020

Backgrounds & Aims: Intratumoural heterogeneity of hepatocellular carcinoma (HCC) is of increasing translational interest. Dismal prognosis is frequently linked to HCC harbouring cancer stem cell (CSC)-features, represented by EpCAM-expression. However, to what extent intratumoural distribution of CSC-features impacts on recurrence after curative resection remains unknown. Hence, we aimed to investigate the spatial heterogeneity of CSC-features and its impact on clinical outcome, identifying high-risk patients amenable to adjuvant treatment.Methods: We designed a tissue microarray (TMA) from patients, who received liver resection between 2011 and 2017. Tumour specimens were sampled at multiple locations (n=3-8). EpCAM-positivity was assessed for intensity and proportion by applying a score dividing three groups: negative (E-/-), heterogeneous-positive (E-/+), homogeneous-positive (E+/+). The groups were further analysed with respect to time-to-recurrence (TTR) and recurrence-free-survival (RFS).Results: We included 341 tumour spots from 75 patients (77% male, median age 66 years, liver cirrhosis/fibrosis 74.6%). Risk factors were alcohol abuse in 23.9%, NASH 16.3%, HBV 14.1%, HCV 17.4% and others 28.3%, representing a typical Western cohort. E+/+ patients experienced a significantly shorter TTR and RFS compared to E+/- (and E-/-) patients (TTR 5 vs. 19 months, p=0.017; RFS 5 vs. 14 vs. 18 months, p=0.016). Only homogeneous EpCAM-positivity correlated with higher AFP levels (>400 ng/ml, p=0.024).Conclusions: Spatial heterogeneity of EpCAM-expression was markedly present. Only homogeneously positive EpCAM-expression correlated significantly with early recurrence, whereas heterogeneous EpCAM-expression was associated with clinical endpoints comparable to EpCAM-negativity. Similar to colorectal cancer, high or low risk features for recurrence could be decisive for adjuvant treatment.
Immediate and Legacy Effects of Snow Exclusion on Soil Fungal Diversity and Community Composition
Authors: Zhang Li , Ren Yuzhi , Yang Kaijun , Li Zhijie , Tan Bo , Liu Yang , Li Han , You Chengming , Liu Sining , Wang Lixia , Yin Rui , Zhang Jian , Xu Zhenfeng
Published: August 2020

Background: Soil fungi play crucial roles in ecosystem functions. However, how snow cover change associated with winter warming affects soil fungal communities remains unclear in the Tibetan forest.Methods: We conducted a snow manipulation experiment to explore immediate and legacy effects of snow exclusion on soil fungal community diversity and composition in a spruce forest on the eastern Tibetan Plateau. The fungal communities were performed by the high throughput sequencing of gene-fragments amplified from forest soil DNA.Results: We found that the Ascomycota and Basidiomycota were the two dominant fungal phyla and Archaeorhizomyces, Aspergillus and Amanita were the three most common genera across seasons and snow manipulations. Snow exclusion did not affect the diversity and structure of soil fungal community in both snow-covered and snow-free seasons. However, the relative abundance of some fungal communities was different among seasons. Soil fungal groups were correlated with environmental factors (i.e., temperature and moisture) and soil biochemical variables (i.e., ammonium and enzyme).Conclusions: These results suggest that the season-driven variations had stronger impacts on soil fungal community than short-term snow cover change. Such findings may have important implications for soil microbial processes in Tibetan forests experiencing significant decreases in snowfall.
ESTADO DEMOCRÁTICO DE DIREITO E A PARTICIPAÇÃO POPULAR NO BRASIL: UMA ANÁLISE A PARTIR DO CONCEITO DE LUIGI FERRAJOLI
Authors: Oliveira de Campos Luciana , Pires Ohlweiler Leonel
Published: August 2020

O presente estudo tem como objetivo propor uma reflexão sobre o Estado Democrático de Direito e o exercício da democracia direta no Brasil à luz do garantismo como paradigma teórico. A análise dar-se-á com base nos aportes de Luigi Ferrajoli, segundo o qual as garantias constitucionais limitam e vinculam os poderes, com implicações de ordem jurídica e democrática, compreendendo desde a separação entre existência e validade nos aspectos formal e substancial até uma teoria quadridimensional da democracia fundada nos direitos políticos, civis, de liberdade e sociais. Sob esse olhar garantista, a participação popular realizada mediante a aproximação dos cidadãos dos centros de decisão está para além do exercício da democracia de forma direta assegurada no texto constitucional, deve ser considerada como importante instrumento nos processos de efetivação dos direitos fundamentais, especialmente dos direitos sociais constitucionalmente assegurados. Adota-se a metodologia qualitativa e a coleta dos dados por meio de pesquisa bibliográfica.
Climate change and its implications for rainfed agriculture in Ethiopia
Authors: Moges Desalew Meseret , Bhat H. Gangadhara
Published: August 2020

This study aims to investigate the spatio-temporal variability and trends in climate and its implications for rainfed agriculture in the Rib watershed, north-western highland Ethiopia from 1986 to 2050. The daily rainfall and temperature records for the period 1986–2017 were used to detect the variability and trends of the current climate using the coefficient of variation, precipitation concentration index, Mann–Kendall test, and Sen's slope estimator. On the other hand, future climate changes (2018–2050) were analyzed based on the Coupled Model Intercomparison Project version 5 (CMIP5) model outputs under under two representative concentration pathway (RCP) scenarios, RCP 4.5 and 8.5. The results showed high inter-seasonal and inter-annual variability of rainfall and temperature in the studied watershed over the last four decades. The annual and Kiremt (June–September) rainfall showed a generally increasing trend, while the Belg (March–May) rainfall exhibited a decreasing trend between 1986 and 2017. Conversely, the minimum, maximum and mean temperature demonstrated increasing trends over the study period although most of the detected trends were statistically insignificant at 5 and 10% level of significance. Future climate analysis results showed an increase in future temperature and annual and Kiremt rainfall while Belg rainfall declined.
Removal of fluoride using magnesium and iron complex hydroxides
Authors: Ogata Fumihiko , Nagai Noriaki , Nagahashi Eri , Kadowaki Natsumi , Saenjum Chalermpong , Nakamura Takehiro , Kawasaki Naohito
Published: August 2020

In this study, metal complex hydroxide materials containing magnesium to iron in molar ratios of 3:1 and 5:1, referred to in this study as Mg-Fe-CH3.0 and Mg-Fe-CH5.0, respectively, were prepared, and their adsorption capability with respect to fluoride ions was investigated. The physicochemical characteristics of adsorbents were determined using scanning electron microscopy and X-ray diffraction, and specific surface area and the number of hydroxyl groups were calculated. The adsorption behaviors and mechanism of fluoride ions were assessed. The adsorption capability of fluoride ions using Mg-Fe-CH3.0 was greater than that using Mg-Fe-CH5.0. In addition, the amount adsorbed depended on the adsorption temperatures; the adsorption was comparatively less at 5 °C than at 25 °C. Adsorption mechanism of fluoride ions was evaluated by elemental distribution analysis and binding energy. The binding energy of fluorine onto Mg-Fe-CH3.0 and Mg-Fe-CH5.0 could be detected after adsorption. Additionally, it was clear that one of the adsorption mechanisms was related to the ion exchange between fluoride ions and chloride ions in the interlayer space of the Mg-Fe-CH3.0 and Mg-Fe-CH5.0 (correlation coefficient 0.923–0.965). This study illustrates that both Mg-Fe-CH3.0 and Mg-Fe-CH5.0 have a high potential for fluoride ion adsorption from the aqueous phase.
Оценки упругих, диэлектрических и оптических характеристик кубического монокристалла BАs
Authors: Давыдов С.Ю.
Published: August 2020

To estimate physical characteristics for cubic BAs crystal Keating’s force constant model and Harrison’s binding orbital method are used. Both harmonic and anharmonic characteristics are considered. Comparison of the obtained results with the experimental data and other author’s calculations shows that the adopted approach is adequate.
Public Perceptions and Attitudes Toward COVID-19 Nonpharmaceutical Interventions Across Six Countries: A Topic Modeling Analysis of Twitter Data
Authors: Doogan Caitlin , Buntine Wray , Linger Henry , Brunt Samantha
Published: August 2020

Background

Nonpharmaceutical interventions (NPIs) (such as wearing masks and social distancing) have been implemented by governments around the world to slow the spread of COVID-19. To promote public adherence to these regimes, governments need to understand the public perceptions and attitudes toward NPI regimes and the factors that influence them. Twitter data offer a means to capture these insights.

Objective

The objective of this study is to identify tweets about COVID-19 NPIs in six countries and compare the trends in public perceptions and attitudes toward NPIs across these countries. The aim is to identify factors that influenced public perceptions and attitudes about NPI regimes during the early phases of the COVID-19 pandemic.

Methods

We analyzed 777,869 English language tweets about COVID-19 NPIs in six countries (Australia, Canada, New Zealand, Ireland, the United Kingdom, and the United States). The relationship between tweet frequencies and case numbers was assessed using a Pearson correlation analysis. Topic modeling was used to isolate tweets about NPIs. A comparative analysis of NPIs between countries was conducted.

Results

The proportion of NPI-related topics, relative to all topics, varied between countries. The New Zealand data set displayed the greatest attention to NPIs, and the US data set showed the lowest. The relationship between tweet frequencies and case numbers was statistically significant only for Australia (r=0.837, P<.001) and New Zealand (r=0.747, P<.001). Topic modeling produced 131 topics related to one of 22 NPIs, grouped into seven NPI categories: Personal Protection (n=15), Social Distancing (n=9), Testing and Tracing (n=10), Gathering Restrictions (n=18), Lockdown (n=42), Travel Restrictions (n=14), and Workplace Closures (n=23). While less restrictive NPIs gained widespread support, more restrictive NPIs were perceived differently across countries. Four characteristics of these regimes were seen to influence public adherence to NPIs: timeliness of implementation, NPI campaign strategies, inconsistent information, and enforcement strategies.

Conclusions

Twitter offers a means to obtain timely feedback about the public response to COVID-19 NPI regimes. Insights gained from this analysis can support government decision making, implementation, and communication strategies about NPI regimes, as well as encourage further discussion about the management of NPI programs for global health events, such as the COVID-19 pandemic.
Undergraduate Medical Competencies in Digital Health and Curricular Module Development: Mixed Methods Study
Authors: Poncette Akira-Sebastian , Glauert Daniel Leon , Mosch Lina , Braune Katarina , Balzer Felix , Back David Alexander
Published: August 2020

Background

Owing to an increase in digital technologies in health care, recently leveraged by the COVID-19 pandemic, physicians are required to use these technologies appropriately and to be familiar with their implications on patient care, the health system, and society. Therefore, medical students should be confronted with digital health during their medical education. However, corresponding teaching formats and concepts are still largely lacking in the medical curricula.

Objective

This study aims to introduce digital health as a curricular module at a German medical school and to identify undergraduate medical competencies in digital health and their suitable teaching methods.

Methods

We developed a 3-week curricular module on digital health for third-year medical students at a large German medical school, taking place for the first time in January 2020. Semistructured interviews with 5 digital health experts were recorded, transcribed, and analyzed using an abductive approach. We obtained feedback from the participating students and lecturers of the module through a 17-item survey questionnaire.

Results

The module received overall positive feedback from both students and lecturers who expressed the need for further digital health education and stated that the field is very important for clinical care and is underrepresented in the current medical curriculum. We extracted a detailed overview of digital health competencies, skills, and knowledge to teach the students from the expert interviews. They also contained suggestions for teaching methods and statements supporting the urgency of the implementation of digital health education in the mandatory curriculum.

Conclusions

An elective class seems to be a suitable format for the timely introduction of digital health education. However, a longitudinal implementation in the mandatory curriculum should be the goal. Beyond training future physicians in digital skills and teaching them digital health’s ethical, legal, and social implications, the experience-based development of a critical digital health mindset with openness to innovation and the ability to assess ever-changing health technologies through a broad transdisciplinary approach to translate research into clinical routine seem more important. Therefore, the teaching of digital health should be as practice-based as possible and involve the educational cooperation of different institutions and academic disciplines.
“Once, Twice and Again!” Kipling’s Works in the Russian Twentieth Century Retranslations
Authors: Kamovnikova Natalia
Published: August 2020

The article traces the evolution of the image of Rudyard Kipling and of the role his works played in the Russian literature and culture. The study is performed on the material of Russian retranslations of Kipling’s poetry and of The Jungle Book, which followed different patterns and contributed differently and at times even dissonantly to the construction of the image of Kipling and his literary legacy in the Soviet Union. Strong competition of big independent publishers in the Russian Empire ensured multiple retranslations of The Jungle Book in order to cater for the demands of the wide readership. The change in political powers in 1917, the nationalization of print, and the focus on education worked towards the development of a very selective approach to the rendering of The Jungle Book, which eventually reduced itself to recycling a limited number of episodes. By contrast, Kipling’s poetry translation took the form of pioneering work, especially in the context of the ban on Kipling in the 1930 – 1970s. These two opposite vectors that Kipling’s translations took in the twentieth century had a tangible effect on the perception of Kipling as an author and inspired the Russian art of the second part of the twentieth century in the fields of literature, music, and film.
Which One is Real?
Authors: Boynudelik Beyza
Published: August 2020

P. 98
With the Bald Ibis
Authors: Boynudelik Beyza
Published: August 2020

P. 118
New Perspectives on Retranslation: The Case of Iran
Authors: Saeedi Samira
Published: August 2020

This paper examines the social aspects of retranslation in contemporary Iran. Foreign classics and award-winning literary books have attracted multiple translations into Persian within a short period of time. For instance, George Orwell’s novella, Animal Farm, has received more than one hundred retranslations in the last 40 years. The aim of this paper is to investigate possible reasons for such an unusually high number of retranslations. By analysing sixteen interviews with Iranian translators and publishers and performing paratextual analysis of four retranslations of George Orwell’s Animal Farm, this paper sheds light on the perceived advantages and disadvantages of retranslation. It does so by drawing on the trust-based approach to the study of translation proposed by Rizzi, Lang, and Pym, and by offering sociological insight into retranslation in contemporary Iran. Four groups of translators are identified: amateur, early career, mid-career, and senior translators. Retranslation for the former two groups is viewed as profitable trade in literary translation market. For the latter two, retranslation is the process of reinforcing trustworthiness at the institutional level that means trust in professionalism of certain Iranian translators and publishers.
Prototype Alarm Sensor Magnet Untuk Pencegah Pencurian Menggunakan Arduino
Authors: Aditya Didit , Cahyono Eko Budi , Nuryasin Ilyas
Published: August 2020

Didaerah Sumenep mulai tahun 2017 dengan total pencurian sebesar 22 kasus, lalu ditahun 2018 sebanyak 30 kasus yang bertempat pada Polres Sumenep. Khususnya , perampokan atau pencurian yang terjadi di minimarket, toko – toko atau rumah kerap kali terjadi saat situasi sepi dan pada malam hari saat toko, minimarket tersebut tutup atau rumah yang ditinggal pemiliknya.  Sehingga sang pemilik mempunyai perasaan khawatir saat minimarket, toko atau rumah tersebut ditutup atau ditinggal pada malam hari. Berdasarkan permasalahan di atas, maka penulis mengangkat topik penelitian guna mencegah pencurian secara dini, dengan menggunakan teknologi Arduino diharapkan dapat lebih mudah dalam penggunaan dan juga memiliki kelebihan kemudahan dalam instalasi. Penggunaan teknologi Arduino Mega 2560 otak pemrosesan dari sebuah alarm. Untuk sensor yang digunakan adalah sensor magnet. Dengan cara menaruh sensor magnet diletakkan pada bingkai pintu lalu didekatkan pada magnet yang berada pada sisi tepi pintu. Apabila pintu dibuka pada jam tertentu maka akan membunyikan sebuah suara.
Pengukuran Kualitas Website Point of Sales System Divisi Bisnis UMM Menggunakan Metric Function Oriented
Authors: Ramadhan Adam Pamungkas , Nuryasin Ilyas , Suharso Wildan
Published: August 2020

Metric Function Oriented merupakan metrik yang menggunakan ukuran fungsionalitas dari suatu aplikasi atau sistem sebagai nilai normalisasi. Dalam hal ini, fungsionalitas dapat diukur secara tidak langsung dengan menggunakan metode Function Point. Function Point ini diturunkan menggunakan hubungan dari pengamatan yang dilakukan berdasarkan ukuran domain informasi perangkat lunak secara langsung yang dapat dihitung dan penilaian perangkat lunak dari sisi kompleksitasnya. Hasil yang didapatkan pada pengumpulan data berupa fungsionalitas dan spesifikasi dari suatu sistem. Untuk perhitungan Unadjusted Function Point, Value Adjustment Factor, dan Function Point hasil yang didapat masing-masing memiliki nilai 247, 0.92, dan 227.24. Sedangkan untuk hasil evaluasi indikator kegagalan berupa nilai kualitas yang dimiliki yaitu 95% yang mana nilai tersebut merupakan nilai kualitas dari website point of sales system milik Divisi Bisnis UMM.
Efek Pembelajaran Creative Problem Solving Berbantuan Media Interaktif Terhadap Hasil Belajar Siswa Pada Mata Pelajaran Dasar Listrik dan Elektronika di SMK Negeri 1 Pariaman
Authors: Fajri Fajri , Usmeldi Usmeldi
Published: August 2020

Proses pembelajaran di SMKN 1 Pariaman masih terpusat pada pendidik dan dalam penyampaian materi pembelajaran pendidik hanya mengandalkan media papan tulis berbantuan bahan ajar seadanya, sehingga kurangnya partisipasi aktif siswa dan hasil belajar siswa banyak di bawah kriteria ketuntasan minimal. Oleh karena itu digunakanlah pembelajaran Creative Problem Solving (CPS) berbantuan media interaktif  untuk mengatasi permasalahan tersebut. Tujuan penelitian adalah untuk melihat seberapa besar efek dari model CPS berbantuan media interaktif  terhadap hasil belajar siswa. Jenis penelitian ini menggunakan penelitian pre experimental dengan desain one group pretest posttest serta subjeknya siswa kelas X TITL 3. Instrumen yang digunakan adalah soal tes berbentuk soal esay. Data di analisis menggunakan rumus effect size. Berdasarkan hasil penelitian model Creative Problem Solving memiliki efek yang besar terhadap hasil belajar siswa pada mata pelajaran dasar listrik dan elektronika di SMKN 1 Pariaman.
TK ‘Aisyiyah Busthanul Athfal Tertua Dan Terbaik di Provinsi Lampung: Sebuah Tinjauan Awal
Authors: Hidayat Bobi , Kuswono K , Agustono Ragil , Hartati Umi
Published: August 2020

Tujuan penilitian ini adalah ingin mengetahui secara historis apa yang menjadi latarbelakang pendirian TK ‘Aisyiyah Bustanul Athfal tertua dan terbaik di Provinsi Lampung. Selain itu yang ingin dipaparkan dalam penulisan artikel hasil penelitian ini adalah bagaimana strategi yang digunakan oleh sekolah untuk mempertahankan keberadaan sekolah hingga saat ini dan menjadi TK ‘Aisyiyah unggulan di Provinsi Lampung. Penelitian ini menggunakan metode penelitian historis dengan menggunakan 4 langkah yaitu 1). Heuristik, 2). Kritik sumber, 3). Interpretasi, dan 4). Historiografi. Untuk merealisasikan langkah penelitian sejarah, peneliti menggunakan teknik pengumpulan data berupa wawancara secara mendalam, observasi lapangan langsung, dan pencatatan dokumen. Hasil penelitian menunjukkan bahwa TK ‘Aisyiyah Bustanul Athfal tertua di Provinsi Lampung yaitu TK ‘Aisyiyah Bustanul Athfal Teluk Betung Selatan yang berdiri pada tahun 1955.  Sedangkan TK ‘Aisyiyah Bustanul Athfal terbaik di Provinsi Lampung yaitu TK ‘Aisyiyah Bustanul Athfal 1 Pringsewu yang berdiri pada tahun 1961. Untuk mempertahankan eksistensi TK, TK ‘Aisyiyah Bustanul Athfal melibatkan masyarakat khususnya anggota ‘Aisyiyah dan masyarakat umum lainya dalam menajalankan kegiatan di TK baik dalam hal tenaga pengajar, sumbangan dana dan pengembangan program-program kerja lainya.
Implementasi Agile Method dalam Pengembangan Jurnal Elektronik di Lembaga Penelitian Non Pemerintahan (NGO)
Authors: Murdiani Deni , Yudhana Anton , Sunardi Sunardi
Published: August 2020

Kebutuhan ketersedian pengelola jurnal nasional yang bereputasi semakin banyak. Terlebih lagi sejak diberlakukannya regulasi kewajiban publikasi bagi mahasiswa sebagai syarat kelulusan. Namun demikian, tidak semua penerbit jurnal dapat mengelola penerbitannya sesuai dengan standar yang telah ditentukan, salah satunya adalah jurnal-junal yang dikelola oleh lembaga penelitian non pemerintahan (NGO). Penelitian ini mengangkat tentang pengembangan jurnal elektronik berbasis Open Journal System (OJS) dengan metode Agile dan Scrum sebagai kerangka kerjanya. Scrum menawarkan pengembangan sistem yang lebih fleksibel dan mampu beradaptasi yang berbasis kolaborasi.  Hasil dari pengembangan ini diuji menggunakan usability systemdengan kuesioner USE (Usefulness, Satisfaction, and Ease of use). Adapun hasilnya, 69,64% respoden menyatakan bahwa sistem pengelolaan jurnal elektronik MAARIF cukup mudah digunakan, cukup mudah dipahami dan cukup mudah dipelajari. 21,42% responden menyatakan sangat mudah digunakan, sangat mudah dipahami dan sangat mudah dipelajari. Hanya 8,9% responden saja yang menyatakan bahwa system pengelolaan jurnal elektronik MAARIF kurang mudah digunakan, kurang mudah dipahami dan kurang mudah dipelajari. Dengan demikian pengembangan jurnal elektronik berbasis OJS versi 3 menggunakan kerangka kerja Scrum dapat diimplementasikan dengan baik menggunakan 3 sprint dengan durasi 34 hari. 

Abstract

The need for the availability of reputable national journal managers. Especially since the enactment of regulation on publication obligations for students as graduation requirements. However, not all journal publishers can manage their issuance in accordance with predetermined standards, one of which is a journal that is managed by a non-governmental research institute (NGO). This study raised the development of an Open Journal System (OJS) based electronic journal with the Agile and Scrum method as its framework. Scrum offers the development of systems that are more flexible and adaptable based on collaboration. The results of this development were tested using the usability system with a USE questionnaire (Usefulness, Satisfaction, and Ease of use). As for the results, 69.64% of respondents stated that the electronic journal MAARIF management system was quite easy to use, quite easy to understand and quite easy to learn. 21.42% of respondents said it was very easy to use, very easy to understand and very easy to learn. Only 8.9% of respondents stated that the electronic journal MAARIF management system was less easy to use, less easily understood and less easy to learn. Thus the development of OJS version 3 electronic journals using the Scrum framework can be implemented properly using 3 sprints with a duration of 34 days.
A REVIEW ON INTERNET OF THINGS ARCHITECTURE FOR BIG DATA PROCESSING
Authors: Akeel Awadh Wid , Salah Hashim Ali , Khalaf Hamoud Alaa
Published: August 2020

The importance of big data implementations is increased due to large amount of gathered data via the online gates. The businesses and organizations would benefit from the big data analysis i.e. analyze the political, market, and social interests of the people. The Internet of Things (IoT) presents many facilities that support the big data transfer between various Internet objects. The integration between the big data and IoT offer a lot of implementations in the daily life like GPS, Satellites, and airplanes tracking. There are many challenges face the integration between big data transfer and IoT technology. The main challenges are the transfer architecture, transfer protocols, and the transfer security. The main aim of this paper is to review the useful architecture of IoT for the purpose of big data processing with the consideration of the various requirements such as the transfer protocol. This paper also reviews other important issues such as the security requirements and the multiple IoT applications. In addition, the future directions of the IoT-Big data are explained in this paper.
Prevalence of Folic Acid And Vitamin B12 Deficiency in Anemic Adolescents
Authors: Mayank Jain  , Girish Ganesh Joag  , Kshirsagar V Y
Published: August 2020

Adolescents may enjoy nourishment trends, macrobiotic weight control plans and semi-starvation regimens in calories, nutrients and minerals. Protein need in a juvenile for every unit body weight is higher than that of grown-up; however, not exactly a quickly developing newborn child. Adolescence has higher nutrient and mineral needs contrasted and individuals all things considered other life stages. A community-based cross-sectional study of 200 school going anaemic adolescents of age group 10 – 19 years. A predesigned semi-organized survey was readied dependent on the audit of writing on Adolescent iron deficiency. The study included 200 anaemic adolescents belonging to two schools, 89 were males, and 111 were females. Male: female ratio was 1.25:1. Among a total of 200 participants, 122 anaemic adolescents belonged to early adolescence. The mean age of anaemic adolescent participants of this study was 13.19 years with a standard deviation of 1.23. among the participants, 137 anaemic adolescents took a vegetarian diet, and 63 anaemic adolescents took a mixed diet. There were three participants underweight according to BMI classification, and 190 had normal range of BMI, 132 adolescents had moderate anaemia (Hb- 8.0 to 10.9 ). Majority of 66.5%(133/200) had Vitamin B12 deficiency anaemia, 72.5%(145/200) had folic acid deficiency anaemia, and 58.5% (117/200) had combined Vitamin B12 and folic acid deficiency anaemia. Prevalence of anaemia in adolescent is a significant public health concern. Supplementation with not only iron and folic acid but also Vitamin B12 may be need of the day. Besides supplementation adequate education regarding quality food, cooking practices and health education is also necessary to be emphasized in adolescents.
Family Planning Services by Mandiri Midwife Practices in Yogyakarta During the Pandemic Period of Covid-19
Authors: Herawati Dian , Fitriana Rosyada Dina , Dian Pratiwi Rita , Neni Wigati Estri
Published: August 2020

Covid-19 has been declared a world pandemic by WHO. Large-scale social restrictions and community appeal to stay at home in an effort to oppose Covid-19 transmission will have an impact on the sustainability of public health services, including family planning services. 54,6% of the total family services planned by midwives are conducted at the private midwifery practice. The purpose of this study was to analyze family planning service visits at the private midwifery practice in Yogyakarta. This study used article quantitative descriptive research method. The population in this study is midwives who have private midwifery practice in the Special Region of Yogyakarta. The results showed that almost all methods of contraception experienced a decrease in service in the private midwifery practice, but the method of family planning through progestin injection did not decrease. As many as 44,7% of midwives provide family services planned through the post placenta Intrauterine Device (IUD) was a method of contraception that was added as a post partum contraception during the main Covid-19 pandemic. Family service protocols have been implemented in the pandemic era with 19% 78% of midwives, online, and using standard personal protective equipment. There was a decrease in family planning services by midwives in the practice of independent midwives in Yogyakarta during the Covid-19 pandemic by 13,8% (from February to April 2020). By the decline predicted to result in a high chance of a baby boom that gives various impacts on the condition of an area. Midwives are expected to improve family planning services after delivery, especially the IUD, and utilize online media. Other efforts can be made through the BKKBN, namely by encouraging not to become pregnant during the Covid-19 pandemic and the existence of free family planning services so that productive partners can routinely control the use of acceptors.
Students are almost as effective as professors in university teaching
Authors: Feld Jan , Salamanca Nicolás , Zölitz Ulf
Published: August 2020

A substantial share of university instruction happens in tutorial sessions—small group instruction given parallel to lectures. In this paper, we study whether instructors with a higher academic rank teach tutorials more effectively in a setting where students are randomly assigned to tutorial groups. We find this to be largely not the case. Academic rank is unrelated to students’ current and future performance and only weakly positively related to students’ course evaluations. Building on these results, we discuss different staffing scenarios that show that universities can substantially reduce costs by increasingly relying on lower-ranked instructors for tutorial teaching. 
Clinical profile and laboratory finding of diabetic foot ulcers from tertiary hospitals in Bali
Authors: Semadi I Nyoman , Setiawan Kelvin , Irawan Hendry
Published: August 2020

Introduction:
Diabetic foot ulcer (DFU), as one of the chronic non-healing wounds, causes a significant financial burden on the healthcare system worldwide. Chronic wounds usually exhibit powerful pro-inflammatory stimuli, as seen in laboratory results.

Aim:
For this reason, we conducted an observational study to obtain the clinical profile, hematological profile, and biochemical profile from our DFU patient laboratory examinations.

Material and methods:
This study was a retrospective descriptive study conducted between March 2016 and December 2018 in Sanglah Hospital, Bali which included a total of 113 patients. The variables included in this study consisted of DFU clinical status, treatment procedures, and laboratory results. We further divided the laboratory results into two groups, haematological and blood chemistry profile. All numerical data were summarized as mean ± standard deviation, and categorical variables were summarized as frequency and percentage.

Results and discussion:
The mean patient’s age was 55.68 ± 10.52 years old. The most of patients were male (54.9%). Leukocytosis was observed in these patients (13.80 ± 6.48 × 109/L) and neutrophil dominated the white blood differential count. There were 35 patients (30.97%) with creatinine levels above 1.3 mg/dL, 73 patients (64.6%) with random blood glucose above 180 mg/dL, and 78 patients (67.3%) with HbA1c levels higher than 53 mmol/mol, even 33 patients (29.2%) with HbA1c more than 86 mmol/mol.

Conclusions:
Some laboratory values have a significant meaning in diabetic foot patients, which can become instruments for the physician in diagnosing, select the most effective treatment, and predict outcome or complications in DFU patients.
THE ROLE OF VISUAL ARTS IN BALANCING ADVERSE SITUATIONS IN INDIA
Authors: Upadhyaya Alpana , Wadhwa Vinny
Published: August 2020

Life has a strange way to unfold. Anything that exists on this Earth comes out of action, but the action only derives its fruits if it’s aligned with your inner world. Adverse situations in life will happen despite all the precautions and safeguards we put in place, in an attempt to prevent or at best avoid their effects. In this, people must concentrate on how to react and control the emotions in this situation. How to overcome negative thinking with the positive one? Positive thinking just means that you approach unpleasantness in a more positive and productive way. Visual Art can be a refuge for intense emotions and illness in adverse situations. Visual art draws people’s attention to details and the environment, which creates a distraction from day-to-day thoughts. No matter whether people chose visual arts to create for ourselves or simply observe or enjoy it.
Detection of Subclinical Mastitis in Dairy Cows using California Mastitis Test and Udder Pathogen
Authors: Qolbaini Evi Nur , Artika I Made , Safari Dodi
Published: August 2020

Subclinical mastitis is an infection of the udder devoid of clinical symptoms, bacteria are one of the causes behind this disease. In the present study, we investigated subclinical mastitis in dairy cows using the California mastitis test (CMT) and udder pathogens from KUNAK (Kawasan Usaha Peternak Sapi Perah) Cibungbulang, Bogor, West Java, Indonesia. We randomly collected 102 milk samples from dairy farms in different stalls. We found that 87 out of the 102 (86 %) milk samples were positive for CMT test with level+1, level+2, and level+3 were 22 %, 45 %, and 33 % respectively. We also identified three different major bacterial groups: staphylococcus, streptococcus, and enterobacteria based on gram staining, oxidase test, and coagulase test. It can be concluded that the case of bovine subclinical mastitis in Kunak Bogor was very high and caused by various bacteria which infected cows.
Comparison of Methods for Glucosamine Production from Achatina fulica Shells Waste
Authors: Maya Siti Maesunah Gilang , Putri Raden Roro Fine Ayu , Sahara Aisyah , Ashari Galuh Adhiyaksa , Zaky Abdurrahman , Andrianto Dimas
Published: August 2020

Osteoarthritis is a degenerative joint disease. This disease occurs when the joint feels painful due to mild inflammation that arises due to activity with the bone of end friction joints. Glucosamine has been proven to stimulate the production of cartilage and inhibit the enzyme that destroys cartilage. Glucosamine which was obtained from the hydrolysis of chitin occurs in a variety of animals such as the shell of crustacea, insects, arthropods, and the shell of molluscs (snail shells). There is a large snail population in Indonesia. Some restaurants and people make use by product snails as food sources. However, this process leaves snail shell as a by product. The high yield of glucosamine produced from snail shells use methods such as reflux+water bath and reflux+magnetic stirrer was 1.47%. Glucosamine hydrochloride was obtained through autoclave at 121 °C and pressure 1 atm for 70 minutes. The presence of chitin, chitosan, glucosamine was confirmed using FTIR spectroscopy. A joint pain ointment was prepared using glucosamine hydrochloride from snail shells concentration at 1 % w/w. Results of this research will be very useful for the reduction of agricultural pests while simultaneously generating a new product that can lift the economic value of snail shells.

Keywords: Chitin, Chitosan, Glucosamine, Osteoarthritis, Snail Shells
Poliextractos de plantas medicinales vs bacterias asociadas a infecciones respiratorias agudas (IRAS)
Authors: Mayo Tadeo Rosa Iris , Espinoza Rojo Mónica , Jiménez Hernández Javier , Godinez Jaimes Flaviano , Damián Nava Agustín , Vargas Alvarez Dolores
Published: August 2020

El presente trabajo de investigación tuvo como objetivo el modelaje para la elaboración de la formulación de un jarabe a base de extractos vegetales de bugambilia, eucalipto, canela, caléndula e ítamo para inhbir el crecimientio de S. aureus y S. pyogenes, bacterias asociadas con las infecciones respiratorias. Se determinó por cromatografía la presencia los metabolitos secundarios en los extractos metanólicos de cada especie, así como también se evalúo la actividad antibacteriana de los extractos y de los jarabes y su capacidad antioxidante. Se encontró que el extracto de eucalipto es el mejor para inhibir a las bacterias, al igual que en su forma de jarabe y el extracto de canela es el mejor antioxidante.
Desarrollo tecnológico para la optimización de la extracción de nuez pecanera
Authors: Morales Magallanes Humberto , Landeros Soriano César , Villegas Berúmen Héctor Gabriel
Published: August 2020

El presente tiene como objetivo mostrar los resultados derivados de una propuesta para laoptimización del proceso de extracción de la nuez (Carya illinoinensis Koch), implementando el uso del desarrollo tecnológico como parte del proceso. Lo anterior, en búsqueda de nuevas herramientas tecnológicas para productores de este fruto y así coadyuvar al desarrollo económico a través la disminución de costos, aumento de la eficiencia y mayor producción mediante la optimización de procesos. Esta investigación selecciona un productor local de la comunidad rural ‘Lo de Nava’, Jerez de García Salinas, Zacatecas. Para la realización del proceso de extracción se analizaron 100 muestras de nuez, de las cuales a 45 se aplicó el proceso de extracción de manera manual y a 55 restantes un proceso optimizado para la separación de la almendra, para recabar los datos de análisis estadístico y conocer los resultados al planteamiento de la investigación. La propuesta para atender la problemática expuesta es el desarrollo de un proceso mecanizado cuyo objetivo consiste en la separación adecuada de la almendra y la cáscara, derivado de un análisis de esfuerzos internos estructurales que faciliten la obtención del fruto, el aumento de la producción y mejoras en su comercialización. El método estadístico utilizado para el análisis de datos es Chi cuadrado (X2 calculada = 8.13, la cual es mayor a X2 critica = 3.841), con un nivel de significancia (α=0.05), la decisión se encuentra en la zona de rechazo para H0; satisfaciendo la aceptación de la hipótesis alternativa H1. Los resultados muestran que la implementación del desarrollo tecnológico en el proceso de extracción de nuez depende del método utilizado para dicho proceso, ya que se tiene mayor extracción del fruto entero en menor tiempo y mayor calidad en relación con los procesos revisados; que refleja aumento de ventas, al contar con una ventaja competitiva que fomente el desarrollo de los productores. Se concluye que las empresas deben orientarse a la innovación de sus procesos mediante el desarrollo tecnológico, los cuales son de importancia para la región donde se realizó el análisis; así mismo, se debe considerar las técnicas que aporten un análisis para detectar sus necesidades, centralizar los esfuerzos y obtener un resultado eficiente.