bluuebunny/crossref_metadata_2025 huggingface dataset:
How do educational Escape Rooms help in improving Soft Skills?
Authors: Manojlovic Heléna
Published: October 2021

Over the past 20 years, work, play, and learning have changed dramatically through technology. Today, we need different skills than in the 20th century, and educational institutions have a key role to play in developing skills. Unfortunately, schools are unable to keep pace with the development of skills that are essential elements of student success. Educators around the world are becoming increasingly aware of the importance of soft skills and play a huge role in ensuring that students are properly prepared for the world of university and work. In contrast, traditional education does not always provide the right tools to improve student success in this area. Following the recent shift from traditional didactic classroom models to the adoption of active learning approaches, escape rooms are increasingly being used in academia as a method for experiential, peer-group, game-based learning. Educational escape rooms are emerging as a new type of learning activity under the promise of enhancing students’ learning through highly engaging experiences. The paper aims to present opportunities to develop soft skills in the school setting using educational escape rooms. The study also reports on testing the self-developed escape room environment for educational purposes.
Working and learning? Features of student employment during COVID-19
Authors: Kocsis Zsófia
Published: October 2021

The literature contains ambivalent research findings on the impact of student employment on study careers. Previous findings also indicated that student employment plays a significant role in interrupting study (Kovács et al. 2019). In our exploratory research, we focused on exploring the employment characteristics of university students during COVID -19. The aim of the study is to investigate the impact of the epidemiological situation on young people's work. To what extent did the epidemic change students' attitudes towards work and study? The research involved university students who regularly work alongside their studies. The online survey was conducted between January and March 2021 (N=235). The majority of the students worked during the epidemiological situation. Contrary to our assumptions, they had no major, long-standing financial problems. An important question for educational research is the relationship between work and learning. A quarter of the respondents had work related to their studies. Some of the undivided student teachers may be considered an at-risk group because they had experiences during their employment that made them insecure about their degree. Our results also showed that students who have study-related work are more committed to a degree and less uncertain about finding a job in their chosen profession.
Synthesis of Nickel-loaded Sulfated Zirconia Catalyst and Its Application for Converting Used Palm Cooking Oil to Gasoline via Hydrocracking Process
Authors: Aziz Ilyas Taufik Abdul , Saputri Wahyu Dita , Trisunaryanti Wega , Sudiono Sri , Syoufian Akhmad , Budiman Arief , Wijaya Karna
Published: October 2021

The synthesis of the nickel-loaded sulfated zirconia catalyst (Ni-SZ) and its application for the hydrocracking process have been carried out. This work has been conducted to determine the activity and selectivity from various Ni concentrations loaded on sulfated zirconia (SZ) in the hydrocracking of used palm cooking oil. The synthesis technique was preceded by sulfation of ZrO2 through incipient wetness impregnation method using H2SO4 solution and then continued with the impregnation of Ni via hydrothermal method employing NiSO4 · 6H2O precursor salt. The hydrocracking process was performed in a fix-bed microreactor at the optimum temperature (350 °C). The SZ loaded with 3 wt% of Ni (Ni-SZ 3) successfully produced the highest liquid product (44.25 wt%) and selectivity on gasoline (100 %). Besides, the gasoline fraction in the liquid product was dominated by unwanted aromatics compounds. The excellent performance of Ni-SZ 3 due to it has high acidity value, specific surface area, and Ni content.
РЕКОНСТРУКЦІЯ ОСОБИСТІСНОЇ ІДЕНТИЧНОСТІ В ПРОЦЕСАХ ІНФОРМАЦІЙНОГО ОБМІНУ В УМОВАХ СУСПІЛЬНИХ ТРАНСФОРМАЦІЙ
Authors: Susska O. O.
Published: October 2021

Обстоюється думка, що в середовищі сучасних процесів, які впливають на визначення особистісної ідентичності, велику вагу має простір масової комунікації. Звертається увага на те, що в цьому просторі місце друкованих засобів поступово займає інтернет, а радіо й телебачення за впливом на коло спілкування і духовний світ людини, хоч і досі посідають перші місця, але суттєво змінюють свої методи й засоби впливу. Стверджується, що протидіяти зовнішньому тиску істотно допомагають ефективні комунікативні зв’язки: саме завдяки глибокому корінню ідентичності особистість зберігає надійний зв’язок між сутнісними пластами свого “Я”. Наголошується, що сам характер спілкування та його розвиток значною мірою залежать від інтересів особистості і тих інформаційних потреб, які задовольняє зміст матеріалів мас-медіа. Зауважено також, що не меншу роль у цьому процесі відіграє усвідомлення людиною особистісної ідентичності та рівень культури споживання продукції масової комунікації.
PREDICTING THE FUTURE AND SATISFACTION WITH LIFE
Authors: Tytarenko T. M.
Published: October 2021

According to our results, increase in productivity of personal prediction has a positive influence on life satisfaction. The present research explores what role the various types of future prediction play in personal life satisfaction. The study focuses on some psychological time phenomena: desires, life choices, aspirations, motivations. To influence personal well-being the desires might be mature, productive, strong and adequately assessed the current life situation. For high level of well-being intrapersonal desires are more important than interpersonal ones. The life choice determining the horizon prediction leads to the transformation of meanings due to the development of new causal sequences of life-satisfaction. The satisfaction with own self and own life world grows when a person makes life-changing decisions from some alternatives. There are the criteria of readiness for significant choices to increase life-satisfaction: self-organizing; psychosemantic; subjective; functional; operational. The stages of life aspirations include communicative semiotization for defining unconscious ambitions and the registration of the forecast as an underway to the desired plot of worthy life, the narration activation leads to the verbal form of the forecast as a desirable plot of a worthy life, and purposeful creation of the story about decent future life, known as setting the concrete tasks. Motivation-semantic future structuring determines the personal life-satisfaction while taking the narrative form in different contexts of communication. The future structuring which is directly related to the effort to optimize the quality of life is self-creating and re-assessment one; in the 1-st model a person re-assesses adopted values and the source of life changes as changes of own self through the integration of new experience; in the 2-and model the values are already adopted, interpreted, and the movement is due to the changes in life situation.
ЗАСОБИ ПСИХОЛОГІЧНОЇ ПІДТРИМКИ СІЛЬСЬКОЇ МОЛОДІ, ЯКА МІГРУВАЛА В МІСТО
Authors: Hubeladze I. G.
Published: October 2021

Розглядаються основні соціально-психологічні засоби підтримки сільської молоді в процесі її міграції до міста. Обстоюється думка, що переїзд із сільської місцевості до принципово іншого, міського, середовища є складною життєвою ситуацією і може супроводжуватися різного роду дезадаптаційними проявами. Основними деструктивними переживаннями під час міграції можуть бути тривожність, напруженість, розгубленість, безпорадність та песимізм. Обґрунтовується доцільність використання різноманітних напрямів і форм роботи з різними категоріями молодих мігрантів: сільськими старшокласниками на етапі прийняття ними рішення про переїзд, студентами сільського походження та працюючою в місті сільською молоддю. Ефективні засоби мають бути спрямовані на актуалізацію соціальної мобільності сільської молоді, активізацію її самосприйняття в новому середовищі, підвищення рівня рефлексії і вироблення вміння ставити життєві цілі з урахуванням реальної соціальної ситуації та досягати їх. Важливим складником адекватної адаптації названо розширення самосвідомості мігранта – уміння усвідомлено робити вибір і брати відповідальність за його наслідки, тобто постійно самовдосконалюватись у процесі особистісного розвитку. Основні напрями цієї роботи мають бути пов’язані зі стимуляцією розвитку таких особистісних якостей, як самостійність, відповідальність, інтегрованість, а також керованість пізнавальної та емоційної діяльності. Описано авторську програму соціально-психологічного тренінгу соціально-психологічної адаптації студентів сільського походження до міського середовища, яка має п’ять модулів. Метою запропонованого тренінгу є сприяння психологічній адаптації студентів сільського походження до нового соціального середовища, знаходження оптимальних моделей поведінки в міському середовищі, формування навичок конструктивного спілкування та ефективної взаємодії із жителями міста. Програму апробовано практичними психологами низки закладів вищої освіти, які підтвердили її ефективність і доцільність використання в роботі із студентами сільського походження.
ДУХОВНО-СИМВОЛІЧНА ПОКОЛІННА ЄДНІСТЬ: ВІЛЬГЕЛЬМ ДІЛЬТЕЙ І ХОСЕ ОРТЕҐА-І-ҐАССЕТ
Authors: Dovhan N. O.
Published: October 2021

У контексті аналізу особливостей конструювання поколінного простору науковцями романтично-гуманітарного підходу виокремлено ідеї пошуку сутності духовно-символічної поколінної єдності і пов’язування історичних подій з конструюванням поколінної реальності. Обґрунтовано необхідність визначення атрибутивних ознак поколінності в працях Вільгельма Дільтея і Хосе Ортеґи-і-Ґассета як теоретичного підґрунтя пізнання феномену поколінності. Здійснено порівняльний аналіз різниці генеалогічних та філософсько-історичних позицій науковців у трактуванні поняття покоління. Виявлено загальні ознаки, за якими Дільтей і Ортеґа об’єднували покоління в групу осіб (єдина “зона” дат народження, історичний досвід у роки становлення, соціальні відносини, спільні культурні тенденції, національні й етнічні форми, мовні особливості, територіальне розташування). Представлено показники поколінної єдності через константи духовної сутності, її ознаки, функціональність, автентичність та ін. Проаналізовано природничі і духовні поколінні антитези в поєднанні життя і досвіду, минулого і сучасного, змінного і незмінного. Визначено, що періоди функціонування поколінь мають обмежений термін за генеалогічним принципом, а соціальні еволюційні курси духовних рухів пов’язані з поколінним хронологічним виміром психічного часу, формою суспільного життя і набутим досвідом (Дільтей), при цьому період домінування покоління сучасників над їхніми пращурами і нащадками обмежується лише п’ятнадцятирічним часовим відрізком (Ортеґа). У результаті аналізу змінних і незмінних констант поколінного феномену з’ясовано, що Дільтей пов’язує особливості еволюційного історичного шляху конструювання духовного світу та історичні знання поколінь, а Ортеґа, навпаки, наголошує на незмінності субстанції духовної суті – “душі і тіла” як психофізіологічного суб’єкта, і ритму історичних змін у світі переплетених життів, колективних вірувань. Зроблено висновок, що трактування сутності динамічних зв’язків поколінь, поглиблені уявлення про перебіг поколінних генетичних процесів, визначені фактори пояснення духовно-символічної єдності поколінь можна розглядати як теоретичне підґрунтя пізнання феномену поколінності науковцями романтично-гуманітарного підходу.
Galerkin Approximations for the Solution of Fredholm Volterra Integral Equation of Second Kind
Authors: Akhia Asma Akter , Saha Goutam
Published: October 2021

In this research, we have introduced Galerkin method for finding approximate solutions of Fredholm Volterra Integral Equation (FVIE) of 2nd kind, and this method shows the result in respect of the linear combinations of basis polynomials. Here, BF (product of Bernstein and Fibonacci polynomials), CH (product of Chebyshev and Hermite polynomials), CL (product of Chebyshev and Laguerre polynomials), FL (product of Fibonacci and Laguerre polynomials) and LLE (product of Legendre and Laguerre polynomials) polynomials are established and considered as basis function in Galerkin method. Also, we have tried to observe the behavior of all these approximate solutions finding from Galerkin method for different problems and then a comparison is shown using some standard error estimations. In addition, we observe the error graphs of numerical solutions in Galerkin method for different problems of FVIE of second kind.
GANITJ. Bangladesh Math. Soc.41.1 (2021) 1–14
Factorizing a Quadratic Expression with Reasoning
Authors: Joarder Anwar H
Published: October 2021

It is not popularly realized that the factorization of a general quadratic expression basically requires solution to a hyperbola and a line. This fact is conspicuously pointed out and a few solutions to the problem are demonstrated that are scattered in the literature. In the high school level, the coefficients of a quadratic expression are mostly integers, and factorization is performed by the popular method of decomposition of the middle term. In this expository note, we have presented it in a simpler way that shows both insight and reasoning into the problem. Some other methods, namely, Linear Method, Average Method and Difference of two Squares Method are also discussed. Depending on the background, a reader may prefer a particular method to the others. The expository nature and artistry in presentation of the paper are expected to make the learning of the topic amusing and instructive.
GANITJ. Bangladesh Math. Soc.41.1 (2021) 15-25
A mathematical analysis of the dynamics of chikungunya virus transmission
Authors: Islam Saiful , Podder Chandra Nath
Published: October 2021

In this paper, a deterministic model for the dynamics of chikungunya virus transmission is formulated and analyzed. It is shown that the model has a disease free equilibrium (DFE) and by using the basic reprodution number (R0) local stability of DFE is proved when  R0 < 1. Also, the global stability of DFE is investigated by Lyapunov function and LaSalle Invariance Principle. We show that there exists a unique endemic equilibrium (EE) of the model which is locally asymptotically stable whenever R0 > 1 and establish the global stability of the EE when R0 > 1, by using Lyapunov function and LaSalle Invariance Principle for a special case. Numerical simulations and sensitivity analysis show that the destruction of breeding sites and reduction of average life spans of vector would be effective prevention to control the outbreak. Controlling of effective contact rates and reducing transmissions probabilities may reduce the disease prevalence.
GANITJ. Bangladesh Math. Soc.41.1 (2021) 41-61
Arterial pharmacokinetics in a patient-specific atherosclerotic artery-a simulation study
Authors: Biswas Sayantan , Sarifuddin - , Mandal Prashanta Kumar
Published: October 2021

Of concern in the paper is a numerical study of endovascular drug delivery in a patient-specific atherosclerotic artery through a mathematical model in which the luminal flow is governed by an incompressible vis- cous Newtonian fluid, and the transport of luminal as well as tissue concentration is modeled as an unsteady convection-diffusion process. An image processing technique has been successfully adopted to detect the edges of the computational domain extracted from an asymmetric (about the centerline of the artery) patient-specific atherosclerotic artery. Considering each pixel as a control volume, the Marker and Cell (MAC) method has been leveraged to get a quantitative insight of the model considered by exploiting physiologically realistic initial, boundary as well as interface conditions. Simulated results reveal that the number as well as the length of separation zone does increase with increasing Re, and the near-wall velocity contour might be important for estimating the near-wall residence time for the pool of drug molecules available for tissue uptake. Results also show that the more the tissue porosity and interface roughness do not necessarily imply the more the effective- ness of delivery, even though they enhance the averaged concentration in the tissue domains, and also the area under concentration diminishes with increasing Peclet number. Thus, the tissue porosity, the Peclet number and various geometrical shapes (interface roughness) play a pivotal role in the dispersion and the effectiveness of drug delivery.
GANITJ. Bangladesh Math. Soc.41.1 (2021) 62-77
Análisis de los programas de responsabilidad social en la imagen corporativa del sector cooperativista de la provincia de Tungurahua
Authors: Caisa-Yucailla Elias David , Tapia-Vasquez Jefferson Stalin
Published: October 2021

Las organizaciones pertenecientes a la economía popular y solidaria son responsables por el cumplimiento de las expectativas que tienen los socios sobre las implicaciones de sus inversiones en los ámbitos medioambientales y la comunidad. La presente investigación tuvo por objetivo determinar el impacto de la responsabilidad social en la construcción de una imagen corporativa positiva en las cooperativas de ahorro y crédito del segmento 3 y 4 de la provincia de Tungurahua. Se aplicó una encuesta a los gerentes de 37 instituciones financieras para evaluación de su imagen corporativa, socios externos, socios internos e inversionistas. La confiabilidad para la aplicación del instrumento fue de 96%. Los hallazgos revelaron que, las instituciones han descuidado al grupo de interés externo e inversionistas. Sin embargo, se evidenció que las cooperativas de ahorro y crédito mantienen su responsabilidad hacia sus empleados (socios internos); es decir, el bienestar de sus socios internos ha sido su prioridad, pues, ha ocasionado el fortalecimiento interno de la organización.

Palabras clave: Responsabilidad social, imagen corporativa, sector cooperativista, stakeholders.

Abstract

Organizations belonging to the popular and solidarity economy are responsible for meeting the expectations that members have regarding the implications of their investments in the environmental and community spheres. The objective of this research was to determine the impact of social responsibility in the construction of a positive corporate image in the savings and credit cooperatives of segment 3 and 4 of the province of Tungurahua. A survey was applied to the managers of 37 financial institutions to evaluate their corporate image, external partners, internal partners, and investors. The reliability for the application of the instrument was 96%. The findings revealed that the institutions have neglected the external interest group and investors. However, it was evidenced that savings and credit cooperatives maintain their responsibility towards their employees (internal partners), that is, the well-being of their internal partners has been their priority, since it has caused the internal streng- thening of the organization. Keywords: Social responsibi- lity, corporate image, coope- rative sector, stakeholders.
Contribución de las empresas al mejoramiento social, económico y ambiental, como desarrollo en Colombia
Authors: Serna-Cardona Luis Hernando , Florez-Vergara Juvenal , Lopez-Ortiz Yulieth , Escalante-Manosalva Uberty
Published: October 2021

Como objetivo del estudio, se identificaron las contribuciones que han realizado las empresas al mejoramiento social, económico y ambiental, como desarrollo en Colombia. La investigación fue desarrollada bajo el enfoque cualitativo, con un diseño analítico enmarcado mediante categorías, con una población de 67 empresas, con instrumentos de recolección de información, el cuestionario y entrevista. Entre los resultados se evidenció que las organizaciones no pueden verse como islas, sino parte de la sociedad, con características como: responsable, económica, desarrollo, comunidad, vital importancia, organización, organismos, entorno, sobrevivencia, adaptabilidad, transformación, integridad, valores éticos, políticas públicas, mejoramiento, calidad, vida, medioambiente y solidaria. En conclusión, se debe entender que no se constituyen como un sistema rígido, sino abiertos, comportándose de diferente manera. Se recomienda organizar un plan de acción de mejoramiento social, económico y ambiental que incluya políticas públicas del ambiente local, además de promover y propender a tener una mejor calidad de vida y de la naturaleza, mediante programas innovadores, confiables, responsables y rigurosos.Palabras claves: contribución, empresa, social, economía, ambiental.

Abstract

The objective was to identify the contributions that companies have made to social, economic and environmental improvement, as development in Colombia, it was developed under the qualitative approach, with analytical design framed by categories, with a population of 67 companies, with instruments for collecting Information, the questionnaire and interview. Among the results it was evident that organizations cannot be seen as islands, but part of society, responsible, economic, development, community, vital importance, organization, organisms, environment, survival adaptability, transformation, integrality, ethical values, public policies, improvement, quality, life, environment and solidarity. In conclusion it should be understood that they are not constituted as a rigid system, but open behaving differently. It is recommended to organize a social, economic and environmental improvement plan that includes public policies of the local environment, in addition to promoting and aiming to have a better quality of life and nature through innovative, reliable, responsible 0.and rigorous programs.

Keywords: contribution, company, social, economy, environmental.
Propuesta de un modelo de innovación abierta a un sector de las Pymes de la ciudad de Cuenca-Ecuador
Authors: Calle Marcelo , Cobos Sofia , González María José , Vera-Reino José
Published: October 2021

En la actualidad, las Pymes enfrentan una necesidad notable de transformar su gestión innovadora; por lo tanto, es necesario encontrar las herramientas que potencien toda su capacidad. Para impulsar nuevas prácticas de innovación con visión abierta, es fundamental que la cultura organizacional se transforme a una cultura de innovación, para que pueda adaptar nuevas estrategias y herramientas que generen un cambio de mentalidad y se visualice a las empresas como una comunidad de oportunidades, de conocimiento y crecimiento. Este estudio tiene como objetivo encontrar información que ayude a crear una propuesta de un modelo de innovación abierta, basado en la realidad de las Pymes del sector comercial de venta de partes, piezas y accesorios para vehículos. Se levantaron datos utilizando encuestas cara-a-cara a una muestra aleatoria de los locales comerciales en estudio de la ciudad de Cuenca. La información recolectada condujo a observar los resultados de una baja implementación innovadora en las PYMES de este sector y permitió identificar herramientas que se proponen como una innovación abierta para que se viabilice y direccione de una manera adecuada la información de fuentes internas y externas, para alcanzar mejores resultados que impulsen el crecimiento de las Pymes.

Palabras clave: cultura innovadora, gestión empresarial, innovación abierta, oportunidad, Pymes.

Abstract
Opettajien kokemuksia työn tuunaamisesta koira-avusteisen pedagogiikan avulla
Authors: Mäkelä Liisa
Published: October 2021

Artikkelissa tutkitaan opetustyön tuunaamista ja sitä, miten opettajat kokevat sen vaikuttaneen työn vaatimuksiin ja voimavaroihin sekä hyvinvointiin. Työn tuunaamisen tapa on koira-avusteisen pedagogiikan hyödyntäminen opetustyössä. Aineisto kerättiin haastattelemalla 14 opettajaa, joilla oli kokemusta koira-avusteisesta työstä. Tulokset osoittivat, että työn tuunaamisella työn vaatimukset ja voimavarat sekä lisääntyivät että vähenivät. Pääosin opettajat kokivat muutokset myönteisinä. Vaikka esimerkiksi työn suunnittelu vaati aiempaa enemmän aikaa, koiran läsnäolo luokassa paransi ilmapiiriä, minkä kuvattiin lisänneen hyvinvointia. Kielteisiksi koettuja muutoksia oli vähän, mutta niiden vaikutukset olivat hyvin kielteisiä. Tilanteet koskivat sosiaalisia suhteita ja kielteisiä asenteita koira-avusteista työtä kohtaan. Koiran kanssa työskentely vaikutti positiivisesti opettajien hyvinvointiin muillakin tavoin, esimerkiksi koiran silittämisen koettiin laskevan stressiä. Työyhteisöissä tulisi suhtautua ennakkoluulottomasti erilaisiin työn tuunaamisen tapoihin, sillä näin työntekijän hyvinvointi voi merkittävästikin kohentua. Työn tuunaamisen reunaehdot ja vaikutukset sidosryhmiin tulisi selvittää, sillä epäonnistuessaan menetelmä voi aiheuttaa pettymystä ja työpaikan vaihtoajatuksia.
Sivistys ihmisyyden ytimessä
Authors: Suhonen Riikka , Hjelt Nina
Published: October 2021

Filosofian professori Reijo Wilenius kirjoitti teoksensa alkuaan vapaan sivistystyön aikuiskasvattajille pitämänsä luentosarjan pohjalta. Koska käsitys sivistyksestä muuttuu ajan mukana, on kiehtovaa lukea ajatuksia sivistyksestä neljän vuosikymmenen takaa ja peilata niitä nykypäivään.
Luovuus tutkimuksen tekemisen ja maailman ymmärtämisen tapana
Authors: Wevelsiep Anneliina
Published: October 2021

Kirja kokoaa yhteen tutkimusmenetelmiä, joilla pyritään laajentamaan tiedon ja tietämisen kirjoa yhteiskuntatieteissä. Pontimena luoville, osallistuville ja toiminnallisille tutkimusmenetelmille on tarve tavoittaa ihmisenä olemisesta ja ympäröivästä maailmasta jotain sellaista, mitä perinteisemmät menetelmät eivät tavoita.
”Aikuiskasvatuksen piirissä voi tutkia mitä moninaisempia asioita”
Authors: Heikkilä Mirva
Published: October 2021

Jyväskylän yliopiston opettajalle ja tutkijalle Petteri Eerolalle, 38, opettaminen on vähintään yhtä tärkeää kuin tutkiminen.
Exploring Veteran Teachers' Collaborative Action Research Experiences Through a School-University Partnership: "Old Dogs" Try New Tricks
Authors: Buckley-Marudas Mary Frances (Molly) , Dutton John , Ellenbogen Charles , Huang Grace Hui-Chen , Schwab Sarah
Published: October 2021

This article shares insights from the experiences of three high school practitioners and two university faculty who participated in a school-university-based action research program as a voluntary part of the teachers’ professional development. The three high school practitioners conducted action research projects around questions that stemmed from and were relevant to their own teaching practice.  As part of the action research program, the practitioners were paired with university faculty to support the research. Building on practitioner inquiry traditions and critical case study methodologies, this study used qualitative methods to explore the experiences of practitioner action research processes.  Drawing on in-person meeting notes and reflective memos, four key ideas emerged: Infrastructure, We are all Partners in Education, Engaging Pathway for Experienced Teachers, and Challenges. Insights gained from this inquiry will have implications for professional practices in the areas of school-university partnership, professional development, and action research process.
Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination
Authors: Štěrba M , Šimůnek T , Popelová O , Potáčová A , Adamcová M , Mazurová Y , Holečková M , Geršl V
Published: October 2021

Anthracycline cardiotoxicity represents a serious risk of anticancer chemotherapy. The aim of the present pilot study was to compare the potential of both the left ventricular (LV) filling pattern evaluation and cardiac troponin T (cTnT) plasma levels determination for the early detection of daunorubicin-induced cardiotoxicity in rabbits. The echocardiographic measurements of transmitral LV inflow as well as cTnT determinations were performed weekly for 10 weeks in daunorubicin (3 mg/kg weekly) and control groups (n=5, each). Surprisingly, no significant changes in LV-filling pattern were observed through the study, most likely due to the xylazine-containing anesthesia, necessary for appropriate resolving of the E and A waves. In contrast to the echographic measurement, the dP/dt(min) index obtained invasively at the end of the study revealed a significant impairment in LV relaxation, which was further supported by observed disturbances in myocardial collagen content and calcium homeostasis. However, at the same time cTnT plasma levels were progressively rising in the daunorubicin-treated animals from the fifth week (0.024+/-0.008 microg/l) until the end of the experiment (0.186+/-0.055 microg/l). Therefore, in contrast to complicated non-invasive evaluation of diastolic function, cTnT is shown to be an early and sensitive marker of anthracycline-induced cardiotoxicity in the rabbit model.
Intracellular mediators in regulation of leptin secretion from adipocytes
Authors: Szkudelski T
Published: October 2021

Leptin is a hormone primarily secreted by adipocytes and participating in the regulation of food intake and energy expenditure. Its blood levels usually correlate with adiposity. The secretion of this hormone is affected, among others, by food consumption, insulin, fasting and cold exposure. Regulation of leptin secretion depends on many intracellular events. It is known that the activation of mTOR (the mammalian target of rapamycin) as well as increase in ATP and malonyl-CoA content in adipocytes enhance secretion of leptin. The rise in intracellular cAMP and fatty acids is thought to evoke the opposite effect. Moreover, the undisturbed action of endogenous adenosine in adipocytes and the proper intracellular Ca(2+) concentration in these cells were also found to have an important function in leptin release. The role of mTOR, ATP, cAMP, fatty acids, malonyl-CoA, adenosine and Ca(2+) in the regulation of leptin secretion from adipocytes is discussed.
Influence of PPAR-alpha agonist fenofibrate on insulin sensitivity and selected adipose tissue-derived hormones in obese women with type 2 diabetes
Authors: Anderlová K , Doležalová R , Housová J , Bošanská L , Haluzíková D , Křemen J , Škrha J , Haluzík M
Published: October 2021

PPAR-alpha agonists improve insulin sensitivity in rodent models of obesity/insulin resistance, but their effects on insulin sensitivity in humans are less clear. We measured insulin sensitivity by hyperinsulinemic-isoglycemic clamp in 10 obese females with type 2 diabetes before and after three months of treatment with PPAR-alpha agonist fenofibrate and studied the possible role of the changes in endocrine function of adipose tissue in the metabolic effects of fenofibrate. At baseline, body mass index, serum glucose, triglycerides, glycated hemoglobin and atherogenic index were significantly elevated in obese women with type 2 diabetes, while serum HDL cholesterol and adiponectin concentrations were significantly lower than in the control group (n=10). No differences were found in serum resistin levels between obese and control group. Fenofibrate treatment decreased serum triglyceride concentrations, while both blood glucose and glycated hemoglobin increased after three months of fenofibrate administration. Serum adiponectin or resistin concentrations were not significantly affected by fenofibrate treatment. All parameters of insulin sensitivity as measured by hyperinsulinemic-isoglycemic clamp were significantly lower in an obese diabetic group compared to the control group before treatment and were not affected by fenofibrate administration. We conclude that administration of PPAR-alpha agonist fenofibrate for three months did not significantly affect insulin sensitivity or resistin and adiponectin concentrations in obese subjects with type 2 diabetes mellitus. The lack of insulin-sensitizing effects of fenofibrate in humans relative to rodents could be due to a generally lower PPAR-alpha expression in human liver and muscle.
Mass spectroscopy analyses of rat 2b myosin heavy chain isoform
Authors: Žurmanová J , Maláčová D , Půta F , Novák P , Říčný J , Soukup T
Published: October 2021

We have separated 2b myosin heavy chain (MyHC) isoform from the rat extensor digitorum longus muscle by SDS-PAGE and analyzed it by two subsequent mass spectrometry techniques. After tryptic digestion, the obtained peptides were identified by Matrix-Assisted Laser Desorption/Ionisation reflectron Time of Flight mass spectrometry (MALDI-TOF MS) and sequenced by liquid chromatography tandem mass spectrometry (ESI LC/MS/MS). The analyzed peptides proportionally covered 30 % of the 2b MyHC isoform sequence. The results suggest that the primary structure is identical with the highest probability to a NCBI database record ref|NP_062198.1|, representing the last updated record of rat 2b isoform. Nonetheless, four peptides carrying amino acid substitution(s) in comparison with the NCBI database record were identified.
IT GOVERNANCE OF SENAYAN LIBRARY MANAGEMENT SYSTEM (SLIMS) LIBRARY AND ARCHIVES DEPARTMENT OF EAST KALIMANTAN PROVINCE USING COBIT 5.0
Authors: Arfyanti Ita , Nursobah Nursobah , Rajiansyah Rajiansyah
Published: October 2021

The existence of an information system in the Library and Archives Department of East Kalimantan needs to be properly maintained and supervised so that the organizational system is in line with the agency's goals. One way to ensure this is to conduct an information system performance analysis. This study uses the Control Objective for Information and related Technology (COBIT) version 5.0, which is a best practice that provides activities managed by the IT organizational structure within a framework in the form of a product, to focus on execution and control that has been made from experts from the field of technology governance Information. This practice can maximize IT investment, to assess if there are errors in providing measurements made and delivering services. Therefore, in order to achieve the target, this research was carried out using the COBIT 5.0 framework in order to be able to analyze an information system performance at the Library and Archives Department of East Kalimantan. The results of this study indicate that MEA01 is at level 5 (Optimizing Process), MEA02 is at level 3 (Established Process), MEA03 is at level 2 (Managed Process). In this case the Regional Library and Archives Office of East Kalimantan to be more efficient in the use of IT requires handling of the factors that influence it so that it is maximal, the use of IT for all employees in the operation of the Senayan Library Management System (SLiMS) and also the person in charge of IT to keep pace with developments technology.
ANALISIS PERANCANGAN E-COMMERCE TART & CAKE FAFA CHEESE BERBASIS WEB
Authors: Kusnandar Kusnandar , Arfyanti Ita , Nursobah Nursobah
Published: October 2021

This study discusses about e-commerce analysis and design at the Fafa Cheese shop. The sales system is still done manually, monthly data reports are still done in recording into a book which can lost sales reports, and there is no price information and tart sold, it is necessary to have the delivery status of the tart sold. The development of this sales information system uses the waterfall development system. This study aims to design an online cake sales application, provide information about prices and cakes sold and provide information that cakes have been sent to customers. The results of this study are the creation of e-commerce design, making it easier to make monthly reports, the availability of price information and cakes sold, and the status of cake delivery if the cake has been sent to the customer.
Reading Rooms for Travelling Cultures: English-Language Reading Rooms in Late Nineteenth-Century France
Authors: Colligan Colette
Published: October 2021

This essay focuses on British and American reading rooms at the end of the nineteenth century in French travel centres such as Boulogne-sur-Mer, Cannes, and Paris. These reading rooms were sites of transit that reveal the travelling cultures of Britons and Americans. They set in motion certain travel sociabilities and practices, suggested various transit routes and itineraries, promoted different cultural and national affiliations and identities, and collected, represented, and displayed anglophone cultures. They operated as microcosms of British and American cultures, offering essentialized experiences and connections with people, behaviour, and things affiliated with home, but this essay shows how they were also social environments that not only reinforced, but also reshaped and interrogated anglophone cultures on the move in British, American, and French cultural territories.
TRENDS IN THE DEVELOPMENT OF DEVICES FOR CONTROL OR GEOMETRIC PARAMETERS OF CONTACT LENSES
Authors: Kilnevaya Maria I. , Mikhailov Igor O.
Published: October 2021

The article shows the relevance of the control of the geometric parameters of contact lenses. The types of lenses, their advantage over glasses, as well as devices for monitoring the radii of curvature of the concave surface of the lens are considered. The shortcomings of the available devices and methods for monitoring contact lenses are revealed. The principle and features of operation of an optoelectronic device for non-contact control of geometric parameters of contact lenses are proposed.
TELESCOPS WITH DIFFERENT MAGNIFICATION
Authors: Kolmogorcev Nikolay I. , Khatsevich Tatiana N.
Published: October 2021

The characteristics of pankratic telescopes are considered. It was found that in most modern models of pancratic telescopes, the ratio of the change in magnification and the ratio of the change in the angle of the field of view are not equal to each other. The synthesis of an optical system with a pacratic change of characteristics in the ocular part in the paraxial approximation was carried out using the methods of computer simulation. The analysis of a particular simulation result made it possible to identify the cause of the revealed inequality.
IDENTIFYING IOT DEVICES IN THE INTERNAL PERIMETER OF THE ORGANIZATION
Authors: Kulbyakina Natalia D. , Peshkow Dmitry E. , Popkov Gleb V.
Published: October 2021

The security problem of IoT devices has been present since their appearance due to the unsafe development of both devices and their components. As a result, there are multiple vulnerabilities in IoT devices. Now things are a little better, secure data transfer protocols have begun to be used, and more attention is being paid to the security of firmware. But still, even new devices don't get security patches or banal updates.
INDICATORS FOR ASSESSING THE ORGANIZATION'S CONTROL OF LICENSE REQUIREMENTS AND CONDITIONS IN TERMS OF MONITORING ACTIVITIES
Authors: Maltsev Gennady D. , Novikov Sergey N.
Published: October 2021

The article uses the works of domestic and foreign scientists in the field of information security, information system security, legislative acts and regulatory documents of the Russian Federation. The purpose of the study is to develop indicators for assessing the organization 's control of license requirements and conditions in terms of monitoring activities. As the importance of information increases, so does the number of problems with her protection. Methods of information theft are being improved, and there are more and more new ways of obtaining it without authorization. Therefore, the problem of information security has become particularly relevant. The methods of protection must meet the requirements, have a license and certificates of the relevant authorities. When performing the work, the literature on the topic was studied: "Regulatory framework". The methods of analysis, generalization, comparison, and classification were used in the work. Development of indicators for evaluating the organization for monitoring license requirements in terms of monitoring activities.
KNOWLEDGE MANAGEMENT IN THE CONTEXT OF INFORMATION SECURITY
Authors: Mongush Amyrtaa K. , Karmanov Igor N.
Published: October 2021

Knowledge of information security is one of important factors in information security management, since 70-80% of information security incidents occurred due to negligence or lack of awareness of employees. This article highlights the importance of sharing information security knowledge and identifies barriers to such sharing.
APPLICATION OF ACTIVE REMOTE SENSING METHODS FOR OIL SPILL DETECTION
Authors: Nazdrachev Pavel I. , Chermoshentsev Alexander Yu.
Published: October 2021

The article describes the implementation of the method for processing radar images from the Sentinel-1 satellite on the territory of the Sakhalin Region, the purpose of which is to detect oil spills. The possibility of using this technique for the prompt detection of oil spills in water areas, as well as for monitoring is shown.
LIQUID LIGHT FILTER FOR THE VISIBLE SPECTRUM BASED ON HYDROPHILIC SOLUTIONS
Authors: Nikitin Konstantin S. , Efremov Victor S.
Published: October 2021

The principal possibility of designing a liquid light filter using hydrophilic solutions is considered. Search for hydrophilic solutions with the most uniform light transmission at all wavelengths of the visible spectrum.
THE PROBLEM OF ENSURING INFORMATION SECURITY AT ENTERPRISES IN MODERN CONDITIONS
Authors: Nikolaeva Kristina A. , Shaburova Aelita V.
Published: October 2021

Today, an urgent problem is the proper provision of information security in organizations and enterprises, since access to protected information can cause significant damage to the company and its financial position. Based on the fact that the greatest attention and protection is required for information in enterprises, this article will consider, of various kinds, the causes of information security violations, as well as the means and methods of protecting this information. The need to protect information is caused by the increase in its importance in recent years, which explains the relevance of this article.
POSSIBILITIES OF APPLICATION OF ACTIVE REMOTE SENSING METHODS FOR AGRICULTURAL LAND MONITORING
Authors: Svoevolina Anastasiya V. , Chermoshentsev Alexander Yu.
Published: October 2021

The article considers the possibilities of using methods of active remote sensing in agriculture, which will improve the accuracy and objectivity of information on the state of crops. As a result of processing a series of Sentinel-1 images at different times, graphs of the values of the backscattering intensity of the radar signal were obtained, from the analysis of which it is possible to trace the dependence of its change for the main groups of agricultural crops and perform their interpretation.
ISSUES OF AUTOMATION OF THE AUDIT IN ACCORDANCE WITH GOST R 57580.2-2018
Authors: Sitskaya Anastasia V. , Tabakaeva Valeria A. , Selifanov Valentin V.
Published: October 2021

The modern world can be characterized by a huge amount of information and computerization of all spheres of human activity. But one of the most valuable information can be considered the information that concerns financial organizations. There are incidents of information security in financial organizations that can lead not only to the violation of the interests of an individual client, but also to the crisis of the financial market of the entire country. Information security audit allows you to detect violations in the organization's information system in a timely manner, which significantly increases the security of information. Often, timely and rapid receipt of a qualitative and quantitative assessment of the level of security allows you to avoid an incident. To improve the accuracy of estimates and reduce the time of their receipt, the application "Audit57580" was developed, the relevance of which is discussed in detail in the article.
FABRY - PEROT TUNABLE FILTERS
Authors: Sodiq Tiamiyu O. , Nikulin Dmitry M.
Published: October 2021

Tunable light filters are widely used for selecting different bands of wavelengths in the UV, visible and IR spectrum. Their advantages are simplicity, accuracy and high mono-chromaticity. By varying magnetic field it is possible to adjust the filter and select desired wavelength if necessary. In the paper a research on tunable light filters based on Fabry-Perot interferometer (FPI) is presented. These light filters can be tuned in the wavelength range from 400 nm to 1000 nm, in IR band of 8 - 12 μm, with spectral pass band width between 0.5 μm and 1 μm, out of band rejection than 10꞉1 with a resolution of 0.5 - 1.5μV.
SELECTION OF CONTROL PARAMETERS OF ANTI-VIRUS PROTECTION IN INTELLIGENT SYSTEMS
Authors: Tabakaeva Valeria A. , Karmanov Igor N. , An Vladimir R.
Published: October 2021

This article discusses the problem of choosing the settings for managing anti-virus protection systems in intelligent systems. The analysis of antivirus systems is carried out, the main types of antivirus systems are highlighted, their main differences, pros and cons of different approaches. Based on the analysis performed, the control parameters were selected.
DEVELOPMENT OF CRITERIA FOR ASSESSMENT OF CONFORMITY WITH THE SAFETY REQUIREMENTS AT THE INFORMATION FACILITY
Authors: An Vladimir R. , Tabakaeva Valeria A. , Selifanov Valentin V.
Published: October 2021

This article discusses the problem of assessing the state of the security level of protected information. The problem lies in the lack of an approved methodology and inadequate training of specialists in the field of cybersecurity auditing. The aim of the study is to develop criteria for assessing compliance with information security requirements. As a result of the study, assessment criteria were obtained with a normalized scale of values and calculation formulas, developed on the basis of the hierarchy analysis method.
ABOUT THE CHOICE OF THE INITIAL SIDE OF A SPHERICAL GLASS LENS PROCESSING
Authors: Gurin Danil A.
Published: October 2021

The article analyzes the choice of the initial side of a spherical glass lens processing. The analysis was carried out on the basis of a survey of employees of the optical shop and familiarization with the description of a typical technological process for manufacturing lenses at one of the instrument-making enterprises in Novosibirsk, as well as by a retro-review of technical publications on the manufacture of optical parts. Two schemes of decision-making about the initial side of spherical lens processing are revealed: selection (assignment) or calculation by formula. The results of the analysis are formulated and the tasks of further research are defined.
DEVELOPMENT OF A PROJECT TO CREATE A PROTECTED CORPORATE NETWORK USING VPN TECHNOLOGIES
Authors: Dvornikova Olga A. , Popkov Gleb V.
Published: October 2021

At the moment, using a VPN connection is popular among Internet users. 2020 showed the need to create a corporate remote network for organizations of all spheres. VPN technology allows using special programs to unite individual computers and local networks to protect the transmitted information. When connecting to a server located in the VPN public access network, the technology forms a channel that is protected by information using encryption algorithms.
CAPABILITIES OF THE SYSTEM «1C: ENTERPRISE» AND GEOSPATIAL SOLUTIONS IN THE FIELD OF SPATIAL DATA MANAGEMENT
Authors: Zuev Vladislav A. , Voronkin Evgeniy Yu.
Published: October 2021

The article presents the ways integrating the "1C:Enterprise" software with various application solutions, including geoinformation systems. The purpose of the study is to consider various ways of interaction between "1C:Enterprise" and GIS systems. Various protocols that facilitate integration with such systems, as Open Data Protocol (OData), Simple Object Access Protocol (SOAP), as well as a mechanism for supporting Web-services built into the "1C:Enterprise" platform are considered. Methods of representation of spatial data are given. A functional model of data integration is developed and built on the example of interaction with a fairly common geographic information system ESRI ArcGIS Online. A practical application of the integration of the software "1C:Enterprise" and geospatial data management systems is regarded.