bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Amiodarone Loading Dosage in the Treatment of Postoperative Atrial Fibrillation: High Versus Standard Dose Treatment
Authors: Sarıçam Ersin , Öcal Arslan , Iscanlı Murat Doğan , Bozkurt Engin , Ilkay Erdogan , Cantekin Ömer Faruk
Published: September 2024

Background:

Postoperative atrial fibrillation (POAF) is associated with poor outcomes,
including hemodynamic instability, stroke, myocardial infarction, and death. In hemodynamic stable
patients, the rhythm-control strategy is more advantageous than rate control. Current standard intravenous
amiodarone administration has limited success and a delayed effect; the acute success rate is
44% (8-12 h to several days).

Purpose:

The aim of this study was to evaluate the effectiveness of higher amiodarone loading dosage
to restore sinus rhythm in patients with POAF after noncardiac surgery.

Methods:

This is a prospective, randomized, controlled single-center study. The study included 39
patients with POAF, divided into group I (n=27) (intravenous 600 mg amiodarone loading dosage
over 2 h and infusion of 50 mg/h over a 24-h period) and group II (n=12) (standard protocol; 300 mg
of bolus intravenously in 30 min and infusion of 50 mg/h over a 24-h period). The primary endpoint
of the study was a restoration of sinus rhythm at the 24th hour.

Results:

Baseline clinical, laboratory and echocardiographic characteristics of both groups were similar.
The patients with higher loading amiodarone dosage had earlier restoration of sinus rhythm (2.38
± 1.41 vs 8.66 ± 2.87 h, respectively; p=0.015). There was no significant difference in achieving sinus
rhythm at the 24th hour between both groups.

Conclusion:

Higher loading amiodarone dosage increased early conversions to sinus rhythm compared
with standard amiodarone protocol in patients with POAF.
Mapping the Landscape of Global Anticancer Organometallics Research: A Systematic Review
Authors: Ur Rehman Tanzeel , Abdulaziz Alnaam Yaser , Zahid Misbah , Algethami Jari S.
Published: September 2024

Aim:

Due to interdisciplinary research, many innovative concepts have been merged that
seemed to be impractical. Recently, medicinal organometallic chemistry has made remarkable progress,
but the latency of these compounds has not been fully exploited. This systematic review has
examined the published literature on anticancer organometallic chemistry across countries, science
fields, and organizations involved in organometallics research for cancer.

Method:

The study data related to anticancer organometallics were searched from Scopus between
2085 and 2022. Biblioshiny and VOS Viewers were used to analyze and visualize patterns in scientific
literature derived from Scopus.

Results:

Publications on organometallic compounds have been found to contribute to, on average,
1.02% per year, accounting for 94.3% of the total scholarly work published in the last two decades
since 2003. However, research productivity has been found to be steadily improved, with 81.5% of
all publications produced between 2011 and 2022. The countries possessing the highest published
work have been found to be China, the UK, and Germany. The leading institutions, the University
of Warwick, United Kingdom, and the University of Auckland, New Zealand, have topped the list
of organizations with the most publications. Although the use of medicinal organometallics for
cancer has become widespread over the last two decennaries, there has been a notable influx of
groundbreaking scientific publications in recent years.

Conclusion:

The findings of this study may enable researchers to envision potential future scenarios
for scientific collaborations involving the utilization of organometallics in the treatment of cancer.
This study may provide aspiring and current researchers with the necessary tools and
knowledge to effectively pursue their research endeavors for scientific collaborations investigating
the use of anticancer organometallics in the medicinal field. The areas, such as ruthenium with
reactive oxygen species and angiogenesis, represent opportunities for future investigation and innovation.
Recent Advances in Anticancer Research of Osmium and Rhodium Complexes
Authors: Kostova Irena
Published: September 2024

Although platinum and ruthenium complexes have been clinically recognized to be the
most efficient metal-based anticancer candidates, applied in a wide range of cancer cell lines, their
serious toxic effects and drug resistance require the necessity for new metal antitumor complexes.
There is excessive interest in the design of new Pt-group metal complexes, including osmium and
rhodium, which have revealed great chemotherapeutic potential. They have demonstrated modes of
action that differ from those of the most broadly-used in clinical practice platinum- and rutheniumbased
compounds. Os and Rh complexes are equipotent to their platinum and ruthenium analogues.
Many Os- and Rh-based complexes with strong antitumor activity and low toxic effects have been
developed and recognized for their antineoplastic activity in the last few years. Some of them have
exposed different action profiles from the conventional anticancer metal complexes. That is why
they might serve as a possible alternative that deserves more investigation, though limited studies
on their biological effects have been reported, which is in contrast with the classical isoelectronic Pt
and Ru complex compounds. Studies of Os and Rh complexes are currently attracting scientific
attention. Recent developments of this interesting class of novel chemotherapeutic agents have been
reviewed.
Major Depression in Comorbidity with Substance use Disorders: Patients’ Features and Clinical-Neurobiological Rationale of Antidepressant Treatments
Authors: De Filippis Sergio , Martinotti Giovanni , Nicoletti Ferdinando , Mastrostefano Andrea , Trovini Giada , Pugliese Anna , Di Nicola Marco
Published: September 2024

The frequent co-occurrence of major depressive disorder (MDD) and substance use disorders
(SUDs) entails significant clinical challenges. Compared to patients with MDD alone, patients
with MDD and SUD often show increased anhedonia, emotional blunting, and impaired cognitive
function. These symptoms lead to an inability to control cravings, more substance use, increased relapse
rates, and poor adherence to the treatment. This fosters a detrimental cycle leading to more severe
depressive symptoms, functional impairment, and chronicity, culminating in heightened morbidity,
mortality, and healthcare resource utilization. Data on antidepressant treatment of MDD-SUD patients
are inconclusive and often conflicting because of a number of confounding factors in clinical trials
or difficulty in dissecting the specific contributions of pharmacological versus psychological interventions
in real-world studies. The patient's unique clinical features and specific SUD and MDD subtypes
must be considered when choosing treatments. Ideally, drug treatment for MDD-SUD should act
on both conditions and address core symptoms such as anhedonia, craving, and cognitive dysfunction
while ensuring minimal emotional blunting, absence of drug interactions, and no addictive potential.
This approach aims to address unmet needs and optimize the outcomes in a clinical population often
underrepresented in treatment paradigms.
Talent management: Preparing future leaders
Authors: Nurmala Nurmala , Hermina Utin Nina Hermina
Published: September 2024

Effective human resource management is an important factor in preparing future leaders for a company. The process encompasses various strategic stages, including selective recruitment, continuous development, and solid employee retention. In addition, the utilisation of advanced technology and the implementation of diversity and inclusion values play a major role in creating a dynamic and performance-oriented work environment. In practical terms, companies that successfully integrate all of these elements can attract and retain the best talent, and create clear development paths for high-potential employees. This ensures that future leaders have the skills, experience and motivation needed to lead the company to sustainable success. A holistic approach to human resource management also ensures that every individual in the company feels valued and can make maximum contributions. By placing diversity and inclusion as a priority, companies can capitalise on multiple perspectives and diverse talents, which in turn increases levels of innovation and creativity. Advanced technologies, such as predictive analytics and collaboration tools, play an important role in supporting this strategy. Ultimately, companies committed to holistic human capital management not only prepare future leaders but also create a work environment that empowers every employee to thrive and fulfil their full potential.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEBERLANJUTAN UMKM DI ERA PANDEMI COVID-19 (STUDI KASUS KABUPATEN SIDOARJO)
Authors: Basuki Alif fikri , Dias satria
Published: September 2024

MSMEs are one of Indonesia’s national main economic pillars, with the contribution of those in Sidoarjo alone in 2019 of IDR 1.6 trillion. However, their business had to be disrupted by the rocketing cases of Corona Virus Disease (Covid) not long after. They had to struggle with sales decrease, raw material scarcity, distribution clogging, capital deficiency, and production reduction due to labor layoffs. This research aims to identify factors that influence the sustainability of MSMEs in Sidoarjo and measures required by them in order to maintain their sustainability during the pandemic. The scope of this study is the effects of business owner’s resources, environmental carrying capacity, financial management, and communication and information technology usage on the sustainability of MSMEs in Sidoarjo Regency. This research applies multivariate regression analysis and SmartPLS 4 as the statistical tools. The results of the analysis indicate that communication and information technology usage and environmental carrying capacity have significant effects on the sustainability of MSMEs in Sidoarjo during the Covid-19 pandemic, but business owner’s resources and financial management have no significant influence. Therefore, it can be concluded that capital aids, tax incentives, internal support from family, access to information technology, and digital marketing can support the sustainability of MSMEs in Sidoarjo during the Covid-19 pandemic.
PENGARUH PENGGUNAAN DOMPET ELEKTRONIK (E-WALLET) SHOPEEPAY TERHADAP PERILAKU KONSUMTIF MAHASISWA DI KOTA MALANG (STUDI KASUS PADA MAHASISWA FAKULTAS EKONOMI DAN BISNIS UNIVERSITAS BRAWIJAYA)
Authors: Lidya Virginia  , Nurman Setiawan Fadjar
Published: September 2024

The increasingly advanced development of information technology provides new things in the economic sector in keeping up with increasingly modern development. One of them is the emergence of  ShopeePay. ShopeePay is a digital wallet service issued by Shopee and currently very popular with the public because it provides convenience and benefits in terms of trasactions. This study aims to determine the effect of using ShopeePay electronic e-wallet on the consumptive behaviour of student in the city of Malang by tooking at the perceived of ease, perceived of use, and promotion as indicators in this study. The method used is SmartPLS (Partial Least Square). The result showed that perceived of ease, perceived of use, and promotion had a positive and significant effect on the comsumptive behaviour of students in the cinty of Malang.
PENGARUH PROGRAM PELATIHAN TERHADAP KECEPATAN MEMPEROLEH PEKERJAAN (Studi Kasus Dinas Tenaga Kerja Kabupaten Gresik Tahun 2018-2021)
Authors: Rusdiana Vira , Ismail Munawar
Published: September 2024

This study aims to find out whether labor training can increase the opportunity to get a job or not. By taking a case study of manpower training organized by the Gresik Regency Manpower Office, this research found that programs is indeed able to shorten manpower to obtain employment. In addition, this study also reveals other findings, namely, first, age prolongs labor to obtain employment, second, work experience accelerates to obtain employment and, third, education has no effect on the speed of obtaining employment.
PENGARUH PENDIDIKAN, UPAH MINIMUM DAN KESEMPATAN KERJA TERHADAP PENGANGGURAN TERDIDIK DI JAWA BARAT
Authors: Guritno Shinta Ulan , Muljaningsih Sri
Published: September 2024

Unemployment is a phenomenon that occurs in all countries, including Indonesia. Educated unemployed is someone who is looking for a job or has not worked who has a high school education and above. An increase in the workforce that is not proportional to the number of jobs will increase the number of unemployed. This study aims to analyze the effect of education, minimum wages and employment opportunities on educated unemployment in West Java Province in 2018-2021. The method used is a quantitative method using panel data regression tested using the Ordinary Least Squares (OLS) method, where the test uses the Eviews 10 program tool. The results show that education has a positive and insignificant effect on educated unemployment in West Java, minimum wage has a positive and significant effect on educated unemployment in West Java, and opportunity has a positive and insignificant effect on educated unemployment in West Java.
Putative Dual Roles of Bone Morphogenetic Protein 8B (BMP8B) in Disease Progression of Gastric Cancer
Authors: SUN ZHIWEI , CAI SHUO , LIU XIANGYI , JIANG WEN G. , YE LIN
Published: September 2024

Background/Aim: Increased expression of bone morphogenetic protein 8B (BMP8B) in bone marrow and primary tumors of patients with gastric cancer (GC) is associated with disease progression and poor prognosis. However, a reduced expression has also been seen in GCs due to histone acetylation. This study aimed to evaluate BMP8B transcript levels in a large GC cohort and its impact on cellular functions. Materials and Methods: BMP8B transcripts were determined in 319 gastric tumors and compared with 182 adjacent normal tissues using real time PCR, with a further analysis conducted in the TCGA database. Kaplan-Meier plotter analysis was performed to evaluate the correlation between BMP8B and prognosis of the disease. BMP8B knockdown model was employed to determine the effect of BMP8B on the function of GC cells (HGC27). Results: BMP8B mRNA levels were significantly up-regulated in the GC tissues compared with adjacent normal tissues in both TCGA database and our own database from Beijing Cancer Hospital, and high BMP8B expression was associated with poor prognosis. BMP8B is most likely to be involved in the differentiation of GC. Poorly differentiated GC samples presented a significantly reduced BMP8B expression in relation to well-differentiated and moderately differentiated GC. BMP8B knockdown inhibited proliferation of GC cells, while promoted invasion and migration of cancer cells. Conclusion: BMP8B was reduced in GCs, whereas higher BMP8B expression was associated with poor prognosis. BMP8B knockdown inhibited proliferation of GC cells, and promoted invasion and migration. Our results suggest that BMP8B plays dual roles in GC.
Comparison of the Preoperative MRI Evaluation of Glandular Tissue in Subcutaneous Mastectomy and its Influence on the Implant Volume
Authors: FRITSCH HANNA , TUMELTSHAMMER REBECCA , HACHENBERG JENS , WARM MATHIAS , KRUG BARBARA , MALTER WOLFRAM , EICHLER CHRISTIAN
Published: September 2024

Background/Aim: This study examined the influence of preoperative MRI on the choice of implant volume in patients undergoing subcutaneous mastectomy with immediate breast reconstruction. It was postulated that preoperative MRI scans can adequately estimate glandular tissue, which in turn correlates with implant size. Patients and Methods: Preoperative and postoperative MRI scans were used in oncological and prophylactical subcutaneous mastectomy scenarios in 67 cases at the Department of Gynaecology, Breast Cancer Center, University of Cologne, Germany. The preoperative MRI was used to estimate the resected tissue and the postoperative MRI was used to scan for residual glandular tissue. In addition, a correlation found by Malter et al. in 2021 was evaluated with the available data. Results: Preoperative MRIs result in an adequate estimation of resected tissue. This in turn correlates with implant volume. The correlation by Malter et al. also holds when estimating implant volume. The likelihood of residual gland was low if the preoperatively estimate volume was removed. Conclusion: Our results indicate that the use of preoperative and postoperative MRI scans for subcutaneous mastectomies is advantageous. We suggest a routine estimation of glandular tissue, especially for small breasts.
Association of Oncotype-DX HER2 Single Gene Score With HER2 Expression Assessed by Immunohistochemistry in HER2-low Breast Cancer
Authors: DOUGANIOTIS GEORGE , KONTOVINIS LOUKAS , ZARAMPOUKAS THOMAS , NATSIOPOULOS IOANNIS , PAPAZISIS KONSTANTINOS
Published: September 2024

Background/Aim: “HER2-low” is an emerging subtype of breast cancer, with a documented role in predicting response to treatment with novel antibody-drug conjugates. It is defined based on immunohistochemistry, but increasing evidence is challenging this approach as appropriate for identifying the HER2-low subgroup, due to both interobserver variability and limitations of the method itself. Patients and Methods: We retrospectively analyzed data from 430 patients from our departmental databases who had been subjected to an Oncotype-DX score and assessed the correlation of the Oncotype-DX HER2 single-gene score with the HER2 expression on immunohistochemistry. The Oncotype-DX Recurrence Score was also evaluated in the HER2-0 versus HER2-low subgroups. Results: The HER2 single-gene score was found to accurately correlate with the HER2 result on immunohistochemistry, with a statistically significant difference both between HER2-0 and HER2 +1 tumors (p<0.0001), as well as between HER2 +1 and +2 tumors (p<0.0001). There was no statistically significant difference in the recurrence score between the HER2-0 and the HER2-low subgroups. Conclusion: Oncotype-DX single-gene scores for HER2 are a potential surrogate marker for assessing the precise HER2 status, with better reproducibility and less interobserver variance compared to immunohistochemistry. The use of rt-PCR emerges as an alternative method of assessment of the HER2-low subgroup.
Disproportionality Analysis of Osimertinib-related Adverse Events in Elderly Patients Using the Japanese Pharmacovigilance Database
Authors: OMOTO TAKASHI , ASAKA JUNICHI , KUDO KENZO
Published: September 2024

Background/Aim: Osimertinib is a well-tolerated first- or second-line treatment option for elderly patients with epidermal growth factor receptor mutation-positive advanced non-small cell lung cancer. However, the safety of osimertinib in elderly patients requires further investigation. Herein, we identified safety signals for various osimertinib-related adverse events (AEs) in elderly patients by disproportionality analysis using the Japanese Adverse Drug Event Report (JADER) database. Patients and Methods: Data from the JADER database from April 2004 to March 2023 were obtained from the Pharmaceuticals and Medical Devices Agency website. Safety signal detection for osimertinib-related AEs in elderly patients (≥70 years old) was determined using the relative elderly reporting odds ratio (ROR). For osimertinib-related AEs, we extracted 92 preferred terms (PTs) and nine standardized MedDRA queries (SMQs). Results: Safety signals in elderly patients were detected for “Cardiomyopathy (PT)” and “Cardiomyopathy (SMQ)”. The symptoms most frequently associated with “Cardiomyopathy (SMQ)” included “Ejection fraction decreased (PT)”, “Cardiomyopathy (PT)”, and “Stress cardiomyopathy (PT)”. Notably, 53.7% of these outcomes were “Recovery” or “Remission”. The median time to the onset of “Cardiomyopathy (SMQ)” in elderly patients was 85 days (range=2-537 days). Conclusion: We demonstrated that patients ≥70 years potentially have increased osimertinib-related cardiomyopathy compared with patients <70 years. In the future, it is necessary to conduct research focusing on cardiomyopathy in elderly patients.
Predictive Value of the Prostate-specific Antigen Doubling Time for the Effectiveness of Metastasis-directed Radiotherapy in Patients With Oligometastases After Radical Treatment for Non-metastatic Prostate Cancer
Authors: KOGUCHI DAI , TABATA KEN-ICHI , HIRANO SHUHEI , SHIMURA SOICHIRO , SATOH TAKEFUMI , IKEDA MASAOMI , MATSUMOTO KAZUMASA , NIIBE YUZURU , IWAMUR MASATSUGU
Published: September 2024

Background/Aim: Data on metastasis-directed radiotherapy (MDRT) are limited, particularly regarding its association with the prostate-specific antigen (PSA) doubling time (PSADT). The present study evaluated the oncological outcomes of MDRT on the basis of the PSADT in oligo-recurrent prostate cancer patients. Patients and Methods: We retrospectively reviewed clinical data of 35 MDRTs for 29 patients at the Kitasato University Hospital, targeting oligometastatic prostate cancer developed after radical treatment for non-metastatic prostate cancer. Thirty-five MDRTs were classified into the PSADT >3 months (n=25) or PSADT ≤3 months group (n=10). Statistical analyses were performed to compare associations between the two PSADT groups and oncological outcomes such as progression-free survival (PFS) and PSA response after MDRT. Results: There were no significant differences between the two groups in terms of the clinicopathological features. Kaplan-Meier analysis showed that PFS was significantly better in the PSADT >3 months group than in the PSADT ≤3 months group [median: 13.3 versus (vs.) 2.6 months, p=0.046]. Regarding castration sensitivity, the predictive role of PSADT >3 months was maintained in 21 patients who received MDRT without prior salvage hormone therapy (median PFS: 12.7 vs. 2.6 months, p=0.024). In the castration-resistant setting (n=14), the frequency of a decrease in serum PSA levels after MDRT by 90% was 54.5% (median PFS: 23.1 months). Conclusion: MDRT can provide benefit especially for patients with PSADT ≥3 months who had oligo-recurrence after the radical treatment for non-metastatic prostate cancer.
Successful Use of Cemiplimab in a Very Elderly Patient With Cutaneous Squamous Cell Carcinoma
Authors: GAMBALE ELISABETTA , VENTURI GIULIA , GUARINO ADRIANA , VASCOTTO ISMAELA ANNA , PILLOZZI SERENA , DESIDERI ISACCO , DONI LAURA , ANTONUZZO LORENZO
Published: September 2024

Background/Aim: Cutaneous squamous cell carcinoma (SCC) is a common skin cancer with significant morbidity and mortality, particularly in advanced stages. Treatment options for metastatic cutaneous SCC in very elderly patients are limited due to concerns about treatment tolerability and potential adverse effects. Case Report: We report the case of a 90-year-old female patient with metastatic cutaneous SCC who was treated with cemiplimab, a monoclonal antibody (m-Ab) against programmed cell death protein 1 (PD-1), in combination with radiotherapy. The patient received cemiplimab for a limited period, during which time she demonstrated significant clinical improvement without severe adverse events. Radiotherapy was performed as a locoregional treatment with the aim to enhance immunotherapy efficacy. Discussion: This case highlights the feasibility and effectiveness of cemiplimab in very elderly patients with metastatic cutaneous SCC. Despite the common apprehensions regarding the use of immunotherapy in this age group, our patient tolerated cemiplimab well, and the combination with radiotherapy proved beneficial. This suggests that even in very elderly patients, short-term use of cemiplimab, in conjunction with locoregional treatments such as radiotherapy, can be a viable and successful therapeutic approach. Conclusion: Cemiplimab, even in combination with radiotherapy, can be effectively and safely administered to very elderly patients with metastatic cutaneous SCC. This case supports the consideration of immunotherapy, even for a limited duration, as a practical option in the management of advanced cutaneous SCC in elderly patients, expanding the potential treatment strategies for this population.
Strategies for Identifying and Recruiting Women at High Risk for Breast Cancer for Research Outside of Clinical Settings: Observational Study
Authors: Conley Claire C , Rodriguez Jennifer D , McIntyre McKenzie , Niell Bethany L , O'Neill Suzanne C , Vadaparampil Susan T
Published: September 2024

Background

Research is needed to understand and address barriers to risk management for women at high (≥20% lifetime) risk for breast cancer, but recruiting this population for research studies is challenging.

Objective

This paper compares a variety of recruitment strategies used for a cross-sectional, observational study of high-risk women.

Methods

Eligible participants were assigned female at birth, aged 25-85 years, English-speaking, living in the United States, and at high risk for breast cancer as defined by the American College of Radiology. Individuals were excluded if they had a personal history of breast cancer, prior bilateral mastectomy, medical contraindications for magnetic resonance imaging, or were not up-to-date on screening mammography per American College of Radiology guidelines. Participants were recruited from August 2020 to January 2021 using the following mechanisms: targeted Facebook advertisements, Twitter posts, ResearchMatch (a web-based research recruitment database), community partner promotions, paper flyers, and community outreach events. Interested individuals were directed to a secure website with eligibility screening questions. Participants self-reported method of recruitment during the eligibility screening. For each recruitment strategy, we calculated the rate of eligible respondents and completed surveys, costs per eligible participant, and participant demographics.

Results

We received 1566 unique responses to the eligibility screener. Participants most often reported recruitment via Facebook advertisements (724/1566, 46%) and ResearchMatch (646/1566, 41%). Community partner promotions resulted in the highest proportion of eligible respondents (24/46, 52%), while ResearchMatch had the lowest proportion of eligible respondents (73/646, 11%). Word of mouth was the most cost-effective recruitment strategy (US $4.66 per completed survey response) and paper flyers were the least cost-effective (US $1448.13 per completed survey response). The demographic characteristics of eligible respondents varied by recruitment strategy: Twitter posts and community outreach events resulted in the highest proportion of Hispanic or Latina women (1/4, 25% and 2/6, 33%, respectively), and community partner promotions resulted in the highest proportion of non-Hispanic Black women (4/24, 17%).

Conclusions

Although recruitment strategies varied in their yield of study participants, results overall support the feasibility of identifying and recruiting women at high risk for breast cancer outside of clinical settings. Researchers must balance the associated costs and participant yield of various recruitment strategies in planning future studies focused on high-risk women.
Feasibility of Coconut Sugar Business in Cilongok Sub-District, Banyumas Regency
Authors: Faizah Vita Nurul , Darwanto Dwidjono Hadi , Waluyati Lestari Rahayu
Published: September 2024

This research aims to determine the feasibility of processing coconut sugar in the sub-district of Cilongok and to analyze factors that influence coconut sugar production in the sub-district of Cilongok. The primary method of this research is the descriptive-analytical method. The research location was in the sub-district of Cilongok, Banyumas Recency, which has a relatively high potential for coconut sugar to be developed. The selection of locations used the purposive sampling method because the Cilongok sub-district is one of the coconut sugar-producing centers in Banyumas. As many as 60 respondents were gathered by using the purposive sampling method. The data used in this research are primary and were collected through observation, interviews, and recording. The business’s feasibility was analyzed by the R/C ratio, π/C ratio, and Breakeven Point (BEP). Factors that influence production was analyzed by regression analysis. The result showed that the coconut sugar business worth to be developed based on efficiency business analysis, capital productivity analysis, labor productivity analysis, and Breakeven Point (BEP) analysis. Factors that positively affected the coconut sugar production are the number of coconut trees diluted and the workforce, while the negative factor is the fuel used.
The Quality Services of Agrowisata Hortimart Agro Center Bawen Sub-District, Semarang District
Authors: Saputra Mochammad Deni , Mulyo Jangkung Handoyo , Nugroho Agus Dwi
Published: September 2024

The objectives of this research are: 1) determine the level of service quality and the satisfaction of visitors with the service quality provided by agrotourism Hortimart Agro Center and 2) determine the correlation between visitor’s appraisal on the service quality with the characteristics of visitors agrotourism Hortimart Agro Center which is a complement to the analysis, as well as the element of novelty of this research. The method used to determine the service qualities is SERVQUAL and IPA, while customer satisfaction on the quality of service is known by the Customer Satisfaction Index (CSI). Furthermore, the correlation test was applied to determine the correlation between visitor appraisal on service quality and visitor characteristics. This research used primary data that comes from interviewing 40 people as respondents. The result of SERVQUAL shows that three dimensions have negative gap value, namely tangible, responsiveness, and assurance, while the other two dimensions (reliability and empathy) has a positive gap value. IPA analysis results show that there are six attributes located in quadrant I as the main priority for improved performance, ten attributes located in quadrant II which must be maintained its achievement, and seven attributes in quadrant IV are overvalued. There are no attributes that are in quadrant III in the Importance Performance Matrix. The result of the CSI method shows that the level of visitor satisfaction is 82.42%. The value is in the range of 81-100%. Thus the overall visitor is very satisfied with the service performance. The research data’s correlation test obtained the correlation between visitors’ appraisal of the service quality with visitors’ characteristics (age, sex, education, and income).
The Income Risk of Salak Nglumut Farming in Srumbung District, Magelang Regency
Authors: Hariyani Tri Eli , Darwanto Dwidjono Hadi , Perwitasari Hani
Published: September 2024

Salak Nglumut is a potential horticultural crop to be cultivated in district Srumbung, Magelang regency. The high potential is expected to increase the income of salak farmers. However, farmers’ income is influenced by the level of income risks that arise. This study aims to determine the level of income risks and factors that affect the income risk of salak Nglumut farm in district Srumbung Magelang regency. The research location is determined by a purposive sampling method, while the research sample of 50 farmers was determined by a simple random sampling method. The analysis method used to determine the level of income risk is the coefficient of variation (CV), and methods to determine the factors that affect the risk of income is by using multiple regression analysis. The results showed that the risk of salak Nglumut farming income in district Srumbung Magelang regency is about 41.73% or categorized as medium risk. The factors that affect the income risk of salak Nglumut farm in Srumbung district Magelang regency include farming experience, labor cost, and farmer’s age.
Development Strategy of Bhumi Merapi Agro-Tourism in Sleman Regency
Authors: Ulfa Nabila Ayu , Mulyo Jangkung Handoyo , Nugroho Agus Dwi
Published: September 2024

Bhumi Merapi Agrotourism in Sleman regency is one of the agro-tourism spots designed as an educational tourist destination related to agriculture and livestock but has some hurdles in its development. This study aims to know the development strategy of Bhumi Merapi Agrotourism and to determine the priority of the development strategy of Bhumi Merapi Agrotourism. The SWOT analysis (Strengths, Weaknesses, Opportunities, and Threats) and QSPM (Quantitative Strategy Planning Matrix) is used for this research. Based on the SWOT analysis, the results of the study show that the development strategies are (1) Build additional infrastructure/facilities, (2) Promoting tourism products and facilities more intensively, (3) Maintain the natural resources that are owned to remain sustainable, and (4) Advancing Bhumi Merapi Agro-tourism by utilizing the rapid development of technology in the form of the internet. The development strategy priority of Bhumi Merapi Agrotourism obtained from the analysis of QSPM is to promote products and tourism facilities more intensively to the community.
Organic Rice Marketing in Purworejo Regency, Central Java Province
Authors: Yonida Arinda Dwi , Hardyastuti Suhatmini , Masyhuri
Published: September 2024

This study aimed to (1) find out the marketing channels of organic rice, (2) compare marketing margins in the organic rice marketing channels, (3) compare the farmer’s share marketing in the organic rice marketing channel, and (4) compare marketing efficiency in the organic rice marketing channels. The primary method of research uses a descriptive-analytical method. Sampling was conducted using the snowball sampling method with a sample of 30 farmers and eight traders. The method of analysis used to find out the marketing channel is by looking at the product flow from the producer to the final consumer; the marketing margin by looking at the difference in prices at the farmer and the final consumer; farmer’s share by comparing the percentage of prices at the farmer level and the end consumer; and the marketing efficiency determined of the marketing margin and farmer’s share. The results showed that the most channels with the highest margin of organic rice marketing channels were the longest channel, the shortest organic rice marketing channel had the lowest value of the marketing margin. Moreover, the longest organic marketing channel had the smallest farmer’s share value, and the shortest organic marketing channel had the most efficient marketing efficiency.
Technology Adoption Of Farmers To Master Treegrowers Training Program In Gunungkidul District
Authors: Anggraini Analisa , Harsoyo  , Wati Ratih Ineke , Subejo
Published: September 2024

Master TreeGrowers program is a training program for cultivation and marketing of forestplants.The Master TreeGrowers program is held to train the forest farmers to be more skilled and helps the forest farmers to manage their forest better than before as well as to increase the economic value of their forest products. This research is held in Playen, Nglipar, and Girisubo Sub-districts, Gunungkidul Regency. The aims of this research are: (1) Analyzing the farmers’ adoption rate of Master TreeGrowers technology in Gunungkidul Regency and (2) Analyzing of factors that influence the farmers’adoption rate of Master TreeGrowers technology in Gunungkidul Regency. A descriptive method with a quantitative approach is used in this research. This research took 60 samples of the forest farmers with random sampling in Playen Sub-district, Nglipar Sub-dsitrict, Girisubo Sub-district. The samples consist of 30 persons of female farmers and 30 persons of male farmers that take part in Master TreeGrowers Training Program. This research used the proportion test and multiple linear regression method. The result of this research shows that the female farmers adoption rate of Master TreeGrowers technology in Gunungkidul Regency is classified as rare with percentage of 33,32%. The male farmers adoption rate of Master TreeGrowers technology in Gunungkidul Regency is classified as medium stage with percentage of 42,07%. The factors that significantly influence the farmers adoption rate of Master TreeGrowers technology in Gunungkidul Regency is gender type, the farmer perception of Master TreeGrowers program, the role of village apparatus, and the intensity of extension program that followed by farmers.
THE IMPACT OF IMPORT LIBERALIZATION POLICY ON INDONESIAN SOYBEAN IMPORTS
Authors: Damayanti Adhisty Puri , Darwanto Dwidjono Hadi , Masyhuri
Published: September 2024

Indonesian soybean consumption is on the rise, meanwhile soybean production is decreasing, leading to a continuous increase in imports to meet the growing demand. This study aims to (1) assess the trend of soybean imports in Indonesia and (2) identify the factors influencing soybean imports in the country. The research relies on secondary data in the form of time series data spanning from 1991 to 2020. The fundamental methodology employed in this study is quantitative descriptive analysis. The analytical approach adopted is ordinary least squares (OLS), utilizing simple linear regression to discern the trend in soybean imports and multiple linear regression to pinpoint the factors impacting soybean imports. The findings reveal that Indonesian soybean imports exhibit an average annual increase of 72,628.82 tons. Partially, GDP demonstrates a positive and significant influence on the volume of Indonesia's soybean imports. The volume of soybean imports in Indonesia posts the implementation of the import liberalization policy in 1998 surpassed pre-policy levels. Conversely, the exchange rate of the United States Dollar against the Indonesian Rupiah has a negative and significant impact. Additionally, soybean productivity and US soybean producer prices have an insignificant effect on the volume of Indonesian soybean imports.
COMPETITIVENESS AND ECONOMIC STRUCTURE OF BASIC FOOD CROP COMMODITIES IN GUNUNGKIDUL REGENCY
Authors: Salsabila Kharisma Pramesti  , Anjani Hariyani Dwi , Irham
Published: September 2024

Optimizing local potential in food crop-based commodities can increase regional economic development, including in Gunungkidul Regency. Food crop commodities in the area include up land rice, peanuts, cassava, corn, and soybeans. This research aimed at 1) analyzing the competitiveness of food crop base commodities and 2) analyzing the pattern and structure of growth of food crop base commodities in Gunungkidul Regency. The first objective was solved using the Location Quotient (LQ) and Shift-Share Analysis (SSA) overlay method. LQ is used to determine commodities that have comparative advantages. SSA is used to determine commodities that have competitive advantages. The second objective was solved using the Klassen Typology method. Commodities that have comparative advantages and competitive advantages are peanuts and up land  rice. Corn and cassava only have competitive advantages, while soybeans have no competitive or comparative advantages. Peanuts and up land  rice have excellent growth structures, while corn and cassava are developing, and soybeans are relatively underdeveloped, with growth rates and economic contributions that are relatively lower than at the provincial level.
 
Keywords :Food Crops, Klassen Typology, Location Quotient, Shift Share Analysis.
BUSINESS ANALYSIS OF HOUSEHOLD SCALE COW’S MILK INDUSTRY IN SARANGAN VILLAGE MAGETAN REGENCY
Authors: Puspita Sabila Rahmatami , Barokah Umi , Khairiyakh Refa'ul
Published: September 2024

The purposes of this research were to determine the total costs, revenues, profits, efficiency, and risks in the household scale pasteurized cow’s milk industry in Sarangan Village, Magetan Regency. The basic method used is descriptive analysis. Determination of the research location purposively with nine respondents, were taken by the census method. Data collection techniques were collected through interviews, observation, recording, documentation, and questionnaires. The data analysis used is costs, revenues, profits, business efficiency, and risk. The results showed that the business has average total cost production in December 2021 of IDR 9.805.292,00/month. The average revenue is IDR 14.729.444,00/month. So that the average profit is IDR 4.924.152,00/month. The business is already efficient because the efficiency value is 1,54. Therefore, the coefficient of variation is 0,53, and the lower profit limit is minus IDR 253.175,00. These values mean that the business is at risk of experiencing a loss of IDR 253,175.00
Mapping of Leading Fruit Commodities in Malang District
Authors: Ramadhani Putri Aulia , Mazwan M. Zul , Shodiq Wahid Muhammad
Published: September 2024

Indonesia's economic development process is significantly influenced by the agricultural sector. The horticulture subsector is a promising industry that significantly contributes to economic development. Fruit commodities have become increasingly essential in the horticulture subsector and are in high demand by the community. This implies that the classification of a commodity as either basic or superior within the fruit sector is mostly determined by its fruit production. Conversely, commodities with lower fruit production are classified as non-base or non-primed within the sector. The objective of this study is to examine the fruit commodities that form the primary sector in Malang Regency, as well as analyse the fruit commodities that do not form the primary sector in Malang Regency. The employed data analysis method is descriptive quantitative. The findings of this study indicate that the primary or dominant fruit commodities in Malang Regency include apples, duku/langsat fruit, bananas, and salak fruit. The non-primary or non-dominant fruit commodities in Malang Regency include avocados, grapes, star fruit, durian fruit, guava fruit, large orange fruit, Siamese orange fruit, mango fruit, mangosteen fruit, passion fruit, jackfruit, pineapple, papaya, rambutan, sapodilla, soursop, and breadfruit.
CONSUMER SATISFACTION OF COFFEE SHOPS IN PONOROGO REGENCY
Authors: Suksarifanti Anindita Ferbiana , Anjani Hariyani Dwi , Nurhayati Azizatun
Published: September 2024

People’s lifestyle in consuming coffee encourage an increase of coffee shops in Ponorogo. This research aims to: 1) determine the level of consumer satisfaction with the quality of products and services, 2) determine the quality attributes of products and services that perceived important by consumers, 3) determine the quality attributes of products and services that prioritized for improvement. The study was conducted in Ponorogo Regency using convenience sampling method of 100 respondents. Data were analyzed using Customer Satisfaction Index (CSI) and Importance Performance Analysis (IPA). The results showed: 1) CSI is 82.58% for product quality and 85.34% for service quality, both categorized as very satisfied, 2) product quality attributes that perceived important by consumers, namely price affordability, coffee’s menu information, taste, packaging materials, raw materials quality, and suitability of product served with menu, while the attributes of service quality, namely parking availability, toilet cleanliness, comfort of prayer room, neat arrangement of places and provide free space, alacrity of employees tidying up tables, coffee shops cleanliness, serving time speediness, suitability of the menu served, the easiness of information to understand, quality products, products served at a clean table, friendly and polite service, fair service, and good communication from employees, 3) product quality attributes that prioritized for improvement, namely price affordability and coffee’s menu information, while from service quality attributes, namely parking availability, toilet cleanliness, comfort of prayer room, neat arrangement of places and provide free space, and alacrity of employees tidying up tables.
Older People Living Alone and Their Strategies to Face Life: Case Studies from Yogyakarta and West Sumatra
Authors: Insriani Hezti , Mitra Robi , Schröder-Butterfill Elisabeth
Published: September 2024

Across Indonesia, the dominant model for care and support in later life is for older people to live with or near younger family members. However, coresidence with an adult child or other close relative is not always attainable or preferred. There are conditions where older people live alone and cannot fully depend on their family members for care and support, be it for matters related to physical, economic, psychological, or spiritual needs. We examine how older people who live alone, live their lives and what strategies they pursue in facing life. The data presented in this paper are a subset of a larger comparative study on Older People’s Care Networks, which covered five disparate sites across Indonesia. This article focuses on evidence from West Sumatra and Yogyakarta. As our case studies illustrate, older people living alone is a diverse category, ranging from those with children, to those who are de facto childless or actually childless. Their security or vulnerability cannot simply be deduced from their household composition, but they require the understanding of how people create, maintain, and develop supportive networks and how they use agency in actively managing dependence, independence, and interdependence over the life course and in later life.
Feeding Precarity Between State and Capital: Women Workers and Breastfeeding in Cakung Manufacturing Industry
Authors: Shabia Gusti Nur Asla
Published: September 2024

Women constitute the vital workforce in Indonesia's economy, particularly in sectors like garment, textile, and footwear. Despite their economic importance, these industries are characterised by excessive control, pressure, and violence, transforming women into cheap labour and limiting their lives both in the production and social reproduction realm. This study analyses how the discipline of factory work has implications for women workers in their care work, specifically in breastfeeding. Through a qualitative approach, this study uses focus group discussions (FGD) and interviews with women garment and textile industry workers in Kawasan Berikat Nusantara, North Jakarta. The study also analyses the state's response and position in child-feeding matters. The study shows how the regimented nature of factory work, which controls the energy, time, and bodies of women workers, coupled with the absence of job security and protection from the state, limit workers’ capacity to care for their families, particularly to breastfeed their children. Consequently, women workers have to switch to formula milk. I argue that the workers’ reliance on formula milk illustrates a form of neoliberalism in which the state subjugates women workers to the capitalist economy both in the realms of production and social reproduction, forcing them to live in a precarious condition. This potentially will cause health, nutrition, and other quality of life problems for mothers and children in the future.