bluuebunny/crossref_metadata_2025 huggingface dataset:
An Industry Perspective on Risks and Mitigation Strategies Associated with Post Conduct Phase of Clinical Trial
Authors: Bhagat Seema , Kapatkar Vaibhavi K. , Mane Ashish , Pinto Colette , Parikh Devang , Mittal Gaurav , Jain Rishi
Published: October 2019

Aim/objective:

To discuss the potential risks and their mitigation strategies in the post-conduct
phase of the trial.

Background:

Risk management is very important for the clinical trial (CT) to ensure that the trial delivers
its desired outcome(s) in terms of achieving protocol objective and regulatory compliance.

Methodology:

Experienced members of the clinical operation team of a pharmaceutical major underwent
a series of sessions to identify risks associated with the post-conduct phase of CT and developed
mitigation strategies based on own experiences and guidance documents. The risks were categorized
into major, minor and critical risks.

Results:

In the post-conduct phase of a clinical trial, critical risk identified were; failure to communicate
to the stakeholder about premature termination of the trial, mismatch of statistical analysis results
and protocol objective/ regulatory requirement, clinical study report (CSR) noncompliant with
regulatory requirements or delay in CSR preparation. Safety checks suggested to mitigate these risks
including the development of related checklist or shell of relevant documents and its review by clinical
development, quality assurance (QA) and regulatory affairs (RA) team prior to finalization. Additionally,
six major and five minor risk areas were identified and safety checks were suggested.

Conclusion:

Sponsors must act proactively to ensure a systematic approach to conduct various post
conduct trial activities and the plans to mitigate the risks that could affect the quality and outcome of
the clinical trial.

Future Perspective:

A close coordination with all stakeholders for timely anticipation of risks and
execution of mitigation strategies are required for successful CT outcomes.
Comparative Transcriptome Profiling of Disruptive Technology, Single- Molecule Direct RNA Sequencing
Authors: Pradeep Chaithra , Nandan Dharam , Das Arya A. , Velayutham Dinesh
Published: October 2019

Background:

The standard approach for transcriptomic profiling involves high
throughput short-read sequencing technology, mainly dominated by Illumina. However, the short
reads have limitations in transcriptome assembly and in obtaining full-length transcripts due to the
complex nature of transcriptomes with variable length and multiple alternative spliced isoforms.
Recent advances in long read sequencing by the Oxford Nanopore Technologies (ONT) offered
both cDNA as well as direct RNA sequencing and has brought a paradigm change in the
sequencing technology to greatly improve the assembly and expression estimates. ONT enables
molecules to be sequenced without fragmentation resulting in ultra-long read length enabling the
entire genes and transcripts to be fully characterized. The direct RNA sequencing method, in
addition, circumvents the reverse transcription and amplification steps.

Objective:

In this study, RNA sequencing methods were assessed by comparing data from Illumina
(ILM), ONT cDNA (OCD) and ONT direct RNA (ODR).

Methods:

The sensitivity & specificity of the isoform detection was determined from the data
generated by Illumina, ONT cDNA and ONT direct RNA sequencing technologies using
Saccharomyces cerevisiae as model. Comparative studies were conducted with two pipelines to
detect the isoforms, novel genes and variable gene length.

Results:

Mapping metrics and qualitative profiles for different pipelines are presented to
understand these disruptive technologies. The variability in sequencing technology and the
analysis pipeline were studied.
Lewis Acid Promoted, One-Pot Synthesis of Fluoroquinolone Clubbed 1,3,4-Thiadiazole Motifs under Microwave Irradiation: Their Biological Activities
Authors: Patel Navin B. , Parmar Rahul B. , Soni Hetal I.
Published: October 2019

Background:

A Lewis acid promoted efficient and facile procedure for one-pot synthesis
of a novel series of fluoroquinolone clubbed with thiadiazoles motifs under microwave irradiation is
described here. This technique has more advantages such as high yield, a clean procedure, low reaction
time, simple work-up and use of Lewis acid catalyst.

Objective:

Our aim is to generate a biologically active 1,3,4- thiadiazole ring system by using a onepot
synthesis method and microwave-assisted heating. High yield and low reaction time were the
main purposes to synthesize bioactive fluoroquinolone clubbed 1,3,4- thiadiazole moiety.

Methods:

Fluoroquinolone Clubbed 1,3,4-Thiadiazole Motifs was prepared by Lewis acid promoted,
one-pot synthesis, under microwave irradiation. All the synthesized molecules were determined by
IR, 1H NMR, 13C NMR, and Mass spectra. The antimicrobial activity of synthesized compounds was
examined against two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), two
Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes), and three fungi (Candida
albicans, Aspergillus niger, Aspergillus clavatus) using the MIC (Minimal Inhibitory Concentration)
method and antitubercular activity H37Rv using L. J. Slope Method.

Results:

Lewis acid promoted, one-pot synthesis of Fluoroquinolone clubbed 1,3,4-Thiadiazole motifs
under microwave irradiation is an extremely beneficial method because of its low reaction time
and good yield. Some of these novel derivatives showed moderate to good in vitro antibacterial, antifungal,
and antitubercular activity.

Conclusion:

One-pot synthesis of 1,3,4-Thiadiazole by using Lewis acid catalyst gives a good result
for saving time and also getting more production of novel heterocyclic compounds with good antimicrobial
properties via microwave heating method.
How Practitioners’ Understanding of Dialogical Theory Can Enhance Co- Construction of Meaning and Support the Choice and Control of People Who Have Complex Communication Support Needs
Authors: Smith Jacky
Published: October 2019

People who have complex communication support do not have active choice and control in the process of defining how their lives are organised and the support that they receive, despite there being laws and recommendations in place from many bodies such as the United Nations or national governments. The tendency is that the expression of the needs and expectations originate in the opinion of the people closest to the person who has complex communication support needs, rather than from the person themselves. This problem is related to the fact that the dominant model of communication used in this context is based on information transfer and decoding, causing practitioners to regard the need to interpret and negotiate meaning as problematic and somehow differing from other communicative episodes.

This challenge can be met by using a dialogical approach where communication is seen as a process of negotiation where meaning is co-constructed through a sequence of interactions. In situations where practitioners are supported to apply dialogical theory in communication partnerships with people who have complex communication support needs, practitioners’ confidence in co-constructing meaning can grow and communication can be richer, supporting direct consultation.

This article seeks to explore and bring together relevant literature on these topics, highlighting the role of the dialogical approach within the context of the international human rights framework. 

https://doi.org/10.21827/jdbsc.4.31375
Effects of an Intervention Program on Interaction and Bodily Emotional Traces in Adults with Congenital Deafblindness and an Intellectual Disability
Authors: Bloeming-Wolbrink Kitty A. , Janssen Marleen J. , Ruijssenaars Wied A.J.J.M. , Riksen-Walraven J. Marianne
Published: October 2019

Interaction with people with congenital deafblindness (CDB) and an intellectual disability (ID), and recognition of their often unconventional expressions, is complex. In this study, the effects of a two-phase intervention program intended to foster harmonious interaction and the use and recognition of expressions based on a bodily emotional trace (BET) were examined. Five adults with CDB and an ID, and ten of their caregivers participated in the study. A multiple-baseline design was used. Target behaviours were attention by caregiver, attention by participant, confirmation by caregiver, mutual affective involvement, quality of interaction, participant expressions based on a BET, and participant expressions based on a BET recognised by the caregiver. Overall, the results tend to be positive. However, some of the changes were minimal and the results varied considerably among participants. The results of this study suggest that it is possible to foster harmonious interaction and the use and recognition of expressions based on a BET in adults with CDB and an ID. 

https://doi.org/10.21827/jdbsc.4.31376
Development of a Patient-Reported Outcome Instrument for Patients With Severe Lower Extremity Trauma (LIMB-Q): Protocol for a Multiphase Mixed Methods Study
Authors: Mundy Lily R , Klassen Anne , Grier Jordan , Carty Matthew J , Pusic Andrea L , Hollenbeck Scott T , Gage Mark J
Published: October 2019

Background

A current limitation in the care of patients with severe lower extremity traumatic injuries is the lack of a rigorously developed patient-reported outcome (PRO) instrument specific to lower extremity trauma patients.

Objective

This mixed methods protocol aims to describe phases I and II of the development of a PRO instrument for lower extremity trauma patients, following international PRO development guidelines.

Methods

The phase I study follows an interpretive description approach. Development of the PRO instrument begins with identifying the concepts that are important to patients, after which a preliminary conceptual framework is devised from a systematic literature review and used to generate an interview guide. Patients aged 18 years or above with limb-threatening lower extremity traumatic injuries resulting in reconstruction, amputation, or amputation after failed reconstruction will be recruited. The subjects will participate in semistructured, in-depth qualitative interviews to identify all important concepts of interest. The qualitative interview data will be coded with top-level domains, themes, and subthemes. The codes will then be utilized to refine the conceptual framework and generate preliminary items and a set of scales. The preliminary scales will be further refined via a process of conducting cognitive debriefing interviews with lower extremity trauma patients and soliciting expert opinions. Phase III will include a large-scale field test, using Rasch measurement theory to analyze the psychometric properties of the instrument; shortening and finalizing the scales; and determining the reliability, validity, and responsiveness of the instrument.

Results

Phases I and II of this study have been funded. Phase I of this study has been completed, and phase II began in January 2019 and is expected to be completed in November 2019. Phase III will begin following the completion of phase II.

Conclusions

This protocol describes the initial phases of development of a novel PRO instrument for use in lower extremity trauma patients.

International Registered Report Identifier (IRRID)

DERR1-10.2196/14397
Low-Cost Consumer-Based Trackers to Measure Physical Activity and Sleep Duration Among Adults in Free-Living Conditions: Validation Study (Preprint)
Authors: Degroote Laurent , Hamerlinck Gilles , Poels Karolien , Maher Carol , Crombez Geert , De Bourdeaudhuij Ilse , Vandendriessche Ann , Curtis Rachel G , DeSmet Ann
Published: October 2019

BACKGROUND

Wearable trackers for monitoring physical activity (PA) and total sleep time (TST) are increasingly popular. These devices are used not only by consumers to monitor their behavior but also by researchers to track the behavior of large samples and by health professionals to implement interventions aimed at health promotion and to remotely monitor patients. However, high costs and accuracy concerns may be barriers to widespread adoption.

OBJECTIVE

This study aimed to investigate the concurrent validity of 6 low-cost activity trackers for measuring steps, moderate-to-vigorous physical activity (MVPA), and TST: Geonaut On Coach, iWown i5 Plus, MyKronoz ZeFit4, Nokia GO, VeryFit 2.0, and Xiaomi MiBand 2.

METHODS

A free-living protocol was used in which 20 adults engaged in their usual daily activities and sleep. For 3 days and 3 nights, they simultaneously wore a low-cost tracker and a high-cost tracker (Fitbit Charge HR) on the nondominant wrist. Participants wore an ActiGraph GT3X+ accelerometer on the hip at daytime and a BodyMedia SenseWear device on the nondominant upper arm at nighttime. Validity was assessed by comparing each tracker with the ActiGraph GT3X+ and BodyMedia SenseWear using mean absolute percentage error scores, correlations, and Bland-Altman plots in IBM SPSS 24.0.

RESULTS

Large variations were shown between trackers. Low-cost trackers showed moderate-to-strong correlations (Spearman r=0.53-0.91) and low-to-good agreement (intraclass correlation coefficient [ICC]=0.51-0.90) for measuring steps. Weak-to-moderate correlations (Spearman r=0.24-0.56) and low agreement (ICC=0.18-0.56) were shown for measuring MVPA. For measuring TST, the low-cost trackers showed weak-to-strong correlations (Spearman r=0.04-0.73) and low agreement (ICC=0.05-0.52). The Bland-Altman plot revealed a variation between overcounting and undercounting for measuring steps, MVPA, and TST, depending on the used low-cost tracker. None of the trackers, including Fitbit (a high-cost tracker), showed high validity to measure MVPA.

CONCLUSIONS

This study was the first to examine the concurrent validity of low-cost trackers. Validity was strongest for the measurement of steps; there was evidence of validity for measurement of sleep in some trackers, and validity for measurement of MVPA time was weak throughout all devices. Validity ranged between devices, with Xiaomi having the highest validity for measurement of steps and VeryFit performing relatively strong across both sleep and steps domains. Low-cost trackers hold promise for monitoring and measurement of movement and sleep behaviors, both for consumers and researchers.
Sexual Behaviors and Violence in Pornography: Systematic Review and Narrative Synthesis of Video Content Analyses (Preprint)
Authors: Carrotte Elise R , Davis Angela C , Lim Megan SC
Published: October 2019

BACKGROUND

Owing to increasing access to Web-based pornography and concerns about its impact on viewers, many researchers have attempted to systematically analyze the content of pornography.

OBJECTIVE

We aimed to systematically review the results of quantitative content analyses of video-based pornography and identify the degree to which the following behaviors are depicted: (1) sexual behaviors and themes, (2) condom use during sexual behaviors, and (3) aggression and violence.

METHODS

Inclusion criteria for article eligibility were (1) peer-reviewed publications, (2) articles in the English language, (3) articles describing a quantitative content analysis of video pornography, and (4) articles quantitatively examining at least one variable of interest.

RESULTS

A total of 23 studies met the eligibility criteria. Studies varied in scope and definitions of behavioral variables. Condom use was rare, although more commonly depicted in gay male pornography (36%-64% videos) compared with heterosexual pornography (2%-3% videos). Normative sexual behaviors were most frequently depicted in pornography samples (eg, vaginal intercourse in 48%-90% and fellatio in 52%-90% of heterosexual videos; fellatio in 66%-100% and anal intercourse in 70%-80% of gay male videos). Extreme acts of violence (1%-3% videos) and rape (0%-6% videos) were relatively rare. However, more subtle forms of aggression, such as spanking (5%-75% videos), were more common, and unequal sexual relations (eg, domination) were also common. Although estimates varied by study, dominating and violent behaviors were nearly always directed toward women.

CONCLUSIONS

Condom nonuse and gender inequalities are common in pornography, which has implications for the development of healthy sexual relationships among pornography viewers. Higher quality research, including study replication and consistent methodological choices, is needed.
Модифицированная хлопкополиэфирная ткань с наноструктурированным ферромагнитным микропроводом, характеризующаяся низкой горючестью
Authors: Бойправ О.В. , Лыньков Л.М. , Кудрявцева Т.Н.
Published: October 2019

Выполнено рентгенодифракционное исследование хлопкополиэфирной ткани с наноструктурированным ферромагнитным микропроводом, химический состав которой модифицирован пропиткой водным раствором хлористого кальция. Такая ткань обладает низкой горючестью, перспективна для применения в заграждающих конструкциях помещений, подлежащих экранированию от электромагнитных воздействий.
Керамика из нанопорошка диоксида титана: создание методом SPS и свойства
Authors: Лысенко В.И.
Published: October 2019

С помощью метода электроискрового спекания (SPS) на основе наноразмерного порошка диоксида титана создана мелкозернистая (порядка 1 мкм), плотная и твердая керамика (с микротвердостью 16 ГПа).
Дифференциация нанопорошков по размерам частиц на поперечно колеблющейся поверхности
Authors: Калашников С.В. , Номоев А.В.
Published: October 2019

Рассмотрены закономерности так называемого акустического метода разделения ультрадисперсных порошков – перераспределения частиц в узлы и пучности волны на поверхности поперечно колеблющейся пластины. Получены экспериментальные данные по эффективности разделения наночастиц диоксида кремния данным методом. Впервые выявлена зависимость характерного размера разделения частиц от амплитуды колебаний, меньших, чем глубина проникновения акустических вязких волн.
Объединенная группа сканирующей зондовой микроскопии.
Authors: Ахметова А.И.
Published: October 2019

Основное направление объединенной научной группы сканирующей зондовой микроскопии связано с созданием методов и аппаратуры бионаноскопии, а также с развитием их биомедицинских приложений. Одной из первых работ в группе биологической направленности стало исследование различий в морфологии клеточной стенки исходной и генно-модифицированной бактерии.
BALANCED ECONOMIC GROWTH FROM THE STANDPOINT OF MODERN GROWTH THEORIES
Authors: Dragomirović Srđana
Published: October 2019

For decades, world economy has been going through certain processes which vary from expansion to stagnation, and vice versa. Therefore, elements, meaning causes of economic growth, are the key question which dates from the seventies and Adam Smith. National economies integrated through world economy are going through some of the changes which can be explicitly explained by observing the quality of economic growth. For that reason, on one side there are regions with sustainable development and balanced economic growth, but as well, there are economies which are categorized as developing countries due to their expansion. Distortion of world economy, observed through economic growth and inequality of national economies, from the standpoint of economic theories, can be explained by various models of economic growth.
THE INTEROPERABILITY OF EUROPEAN INFORMATION SYSTEMS FOR BORDER AND MIGRATION MANAGEMENT AND FOR ENSURING SECURITY
Authors: Tomaszycki Krzysztof
Published: October 2019

The European Union has been exposed to an increase in illegal migration in recent years. With the migration, the threat of terrorist acts increased, which contributed to reducing the sense of internal security of citizens. The EU citizens expect more effective external border controls and more efficient migration management. Such challenges are addressed by the interoperability of European information systems for border management and migration, as well as ensuring security of the EU. A key element of interoperability is the adaptation of current systems and the development of new ones, especially in the technical aspect. In addition to legal, organizational and logistic activities, it is a key element of the entire system of activities of European institutions and agencies.
AN OVERVIEW OF THE INTERNATIONAL SCIENTIFIC-PROFESSIONAL MEETING AT THE APPELLATE COURT IN NIŠ WITHIN THE PROJECT "STRENGTHENING THE PROBATION AND THE SYSTEM OF ALTERNATIVE SANCTIONS IN MONTENEGRO AND SERBIA" NIŠ, 4TH DECEMBER 2018
Authors: Janković Dijana
Published: October 2019

In the broadest sense, alternative sanctions are criminal law measures that substitute a prison sentence. They are practically parapenal sanctions considering that they lack the actual effectiveness inherent in classical punishment, which is expressed as a complete restriction of some rights or material values. The paper provides an overview of an international scientific-professional meeting of experts held at the Appellate Court in Niš, within the project "Strengthening the Probation and the Alternative Sanctions System in Montenegro and Serbia". Participants of the meeting were members of the Dutch delegation, as well as Serbian judges, public prosecutors, and probation officers. During the presentation of the project and the exchange of opinions and experiences on the application of alternative sanctions in both Netherlands and Serbia, numerous essential questions have been raised regarding the purpose of punishment, the achieved results, and the problems arising in everyday practice in the application of alternative sanctions.
UN SECURITY COUNCIL RESOLUTION 1325 “WOMEN, PEACE AND SECURITY” IN THE LOCAL CONTEXT OF REFUGEE CRISIS: OLD EXPERIENCE OR NEW CHALLENGES?
Authors: Spasic Danijela V
Published: October 2019

Since 2000, the United Nation Security Council (UNSC) has adopted four resolutions on women, peace and security (Resolutions: 1325, 1820, 1888 and 1889). The Resolution 1325 „Women, peace and security“ was adopted on October 31st 2000. This document emphasizes the consequences of bloody conflicts on women and girls and the importance of women's role in peacebuilding and the post-conflict recovery of the country. A particular challenge for its implementation is the refugee crisis in which more than half a million people seeking asylum arrived in Europe starting in 2015. Among them are particularly vulnerable groups of women and children, accommodated in refugee camps and asylum centers. During the stay whose duration is not pre-determined, they are directed towards meeting the needs within the existing local resources (material and human). In this context, the readiness of local communities to ensure the safety and psychosocial well-being of the refugees and migrants, especially women and children, in accordance with the adopted Action Plan for the implementation of Resolution 1325, will come to the fore. The analytical approach in this paper includes the identification of the key determinants of the Resolution 1325 in the local context of the response to the refugee crisis.
WOMEN, PEACE AND SECURITY – THE CASE OF BOSNIA AND HERZEGOVINA
Authors: Mušić Safet
Published: October 2019

Women have had a subordinate position throughout history. Some evidence dates back to ancient Greece, where relations between the master and slaves, father and children, and between men and women were clearly defined in each household. All these relations were based on male domination. Considering the given inequality situation, legal rules were not necessary. Thus, men were "destined" to become rulers and have a dominant role and position in relation to women in family, love, politics or business. Women did not have significant positions in society, nor did they participate to a significant extent in the decision-making processes. In the 20th century, women started raising issues related to gender roles, woman’s role and position in society, and gender equality. In recent years, one of the prominent issues is woman’s role in warfares and peace-keeping activities, and in the national and international security and defense sectors. The paper provides an overview of different international and national documents that promote active and equal participation of women in peace and security activities, both worldwide and in transition countries such as Bosnia and Herzegovina.
Experiências semióticas no GEARTE: nasce a pesquisa leitura de produções audiovisuais
Authors: Pozzi Marion Divério Faria
Published: October 2019

Este trabalho apresenta o percurso trilhado no Grupo de Pesquisa em Educação e Arte – GEARTE, mais especificamente a pesquisa desenvolvida que culminou na tese de doutorado intitulada, Apreensão de sentidos em vídeos contemporâneos. Com base nos estudos das semióticas sincréticas foram realizados exercícios de leitura sobre um corpus de análise constituído por três vídeos contemporâneos, contendo características tanto no seu plano de expressão, quanto no plano de conteúdo, que privilegiassem, em algum aspecto, um olhar mais atento à dimensão do sensível. Tais exercícios buscaram examinar a articulação entre as linguagens visual e sonora, considerando os planos e níveis da linguagem propostos por Hjelmslev, categorias advindas dos estudos cinematográficos articulados aos conceitos de sincretismo e estesia preconizados por Greimas.
Diálogos entre Educação e Arte: GEARTE 21 anos
Authors: Pillar Analice Dutra , Rossi Maria Helena Wagner
Published: October 2019

Diálogos entre Educação e Arte: GEARTE 21 anos
MENINGKATKAN KEMAMPUAN PENALARAN MATEMATIS SISWA MELALUI PENERAPAN PENDEKATAN METAPHORICAL THINKING
Authors: Yanti K.G.D , Pujawan I.G.N , Mahayukti G.A
Published: October 2019

Penelitian ini bertujuan untuk: (1) mendeskripsikan peningkatan kemampuan penalaran matematis  siswa melalui penerapan pendekatan metaphorical thinking, dan (2) mengetahui tanggapan siswa terhadap penerapan pendekatan metaphorical thinking. Subjek penelitian ini adalah siswa kelas IX D SMP Negeri 3 Sukasada sebanyak 30 orang. Data kemampuan penalaran matematis siswa dikumpulkan menggunakan tes kemampuan penalaran matematis bentuk uraian dan tanggapan siswa dikumpulkan menggunakan angket. Masing-masing instrumen telah divalidasi oleh pakar. Data yang terkumpul kemudian dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa kemampuan penalaran matematis siswa mengalami peningkatan. Rata-rata nilai sebesar 45,83 pada siklus I meningkat  menjadi 64,77 pada siklus II dan 77,67 pada siklus III. Demikian pula ketuntasan belajar siswa sebesar 30% pada siklus I meningkat menjadi 63,33% pada siklus II dan 80% pada siklus III. Peningkatan kemampuan penalaran matematis siswa  terjadi karena: (1) siswa terlatih untuk menghubungkan konsep-konsep  matematika  dengan  konsep-konsep  yang  telah  dikenalnya dalam kehidupan sehari-hari; (2) siswa terbiasa menggunakan analogi-analogi, sehingga ingatan terhadap suatu konsep akan semakin lama; dan (3) siswa terlatih untuk aktif dalam memahami konsep dengan menyelesaikan LKS bersama kelompok. Selain itu, tanggapan siswa terhadap pendekatan yang diterapkan berada pada kategori positif, hal tersebut ditunjukkan dari rata-rata skor tanggapan siswa sebesar 59,23.
PENERAPAN QUANTUM LEARNING UNTUK MENINGKATKAN AKTIVITAS BELAJAR DAN KEMAMPUAN MENULIS HASIL KARANGAN DESKRIPSI PADA SISWA KELAS IX SMP
Authors: Suwandiari Ni Nyoman
Published: October 2019

Penelitian ini dilatarbelakangi oleh  rendahnya aktivitas dan kemampuan menulis karangan deskripsi siswa. Penelitian ini bertujuan untuk meningkatkan aktivitas dan kemampuan menulis karangan deskripsi siswa melalui penerapan quantum learning dalam pembelajaran. Aktivitas belajar siswa diambil dengan menggunakan pedoman observasi. Data karangan deskripsi diperoleh dari kemampuan siswa membuat karangan deskripsi yang diberikan ada akhir siklus. Data yang terkumpul dianalisis menggunakan rumus statistik. Hasil pelaksanaan tindakan pada penelitian ini menunjukkan bahwa (1) Penerapan Quantum Learning dapat meningkatkan aktivitas belajar siswa. Pada siklus I rata-rata aktivitas belajar siswa adalah 70 dengan kualifikasi cukup aktif. Siklus II rata-rata aktivitas belajar siswa adalah 86 dengan kualifikasi aktif (2) Penerapan Quantum Learning dapat meningkatkan kemampuan menulis karangan deskripsi siswa. Pada siklus I rata-rata kemampuan menulis karangan deskripsi siswa adalah 60 dengan kualifikasi cukup. Siklus II rata-rata kemampuan menulis karangan deskripsi siswa adalah 79 dengan kualifikasi baik. Dengan demikian Penerapan Quantum Learning dapat meningkatkan aktivitas belajar dan kemampuan menulis karangan deskripsi.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF STUDENT TEAMS ACHIEVEMENT DIVISIONS (STAD) BERBASIS ERGONOMI UNTUK MENIGKATKAN PEMBELAJARAN BIOLOGI SISWA KELAS X MIA1 DI SMA LABORATORIUM UNDIKSHA
Authors: Wijana Nyoman , Sukri Made
Published: October 2019

Tujuan penelitian tindakan kelas ini adalah untuk mengetahui pengaruh penerapan model pembelajaran kooperatif  tipe STAD berbasis ergonomi untuk meningkatkan  hasil belajar siswa kelas X  Mia1 SMA LAB Undiksha. Subyek penelitian ini adalah siswa kelas X Mia1 SMA laboratorium Undiksha sebanyak satu kelas dengan jumlah siswa sebanyak 22 siswa. Objek penelitian ini adalah model pembelajaran kooperatif  tipe STAD berbasis ergonomi dan hasil belajar siswa. Jenis penelitian ini adalah penelitian tindakan kelas (PTK). Penelitian ini dilakukan dalam dua siklus yaitu siklus 1 dan siklus 2 dengan topik pembelajaran yaitu bakteria. Hasil penelitian menunjukkan (1) Penerapan model pembelajaran kooperatif  tipe STAD berbasis ergonomi dapat meningkatkan hasil belajar siswa kelas X Mia1  SMA LAB Undiksha, (2) Pada siklus I ada 8 (36,36%) siswa yang nilainya belum mencapai KKM, sedangkan 14 (63,64%) siswa telah mencapai KKM. Nilai rerata pada siklus I adalah 73,79. Ketuntasan klasikalnya baru mencapai 63,64% dari 75% yang ditarget. Pada siklus II ada 2 (9,09%) siswa yang masih nilainya belum mencapai KKM, sedangkan 20 (90,91%) siswa telah mencapai KKM. Rerata nilai kelasnya sudah melebihi KKM yaitu sebesar 79,36. Ketuntasan klasikalnya adalah sebesar 90,91%.
The calibration of the hailpads upon the Greek National Hail Suppression Program, using the Classical and Inverse Regression methods
Authors: Tsitouridis Kyriakos G.
Published: October 2019

The hailpad, constructed from a plate of Styrofoam, is a simple instrument for recording hailfall. In addition to simply recording the hailfall, calibration of the instrument is required to obtain quantitative measurements of the hail. The calibration is a process leading to a calibration equation, a polynomial establishing a relationship between the diameter of a hailstone and the dent the hailstone is left on the surface of the hailpad. A hailpad network, consisted of 154 instruments, has established inGreece, in the context of the Greek National Hail Suppression Program operating for the protection of the agricultural cultivations from hail damage. For the calibration of the haipads of the network the well known “Energy Matching technique” has adopted and the Inverse Regression method is applied from the beginning for the obtainment of the calibration equation. In the present study along with the Inverse Regression method hitherto applied, the Classical Regression method is examined and presented and inferential statistics are also introduced in both methods in order to establish a more stringent statistical procedure for the calibration of the hailpads. After the theoretical analysis the data from a calibration experiment were analyzed, calibration models obtained using both methods of regression, hail diameters were predicted with the two models when new observations were available and the results compared to each other. The comparison of the two models' predictions showed that the results are almost the same so there is no good reason to replace the hitherto Inverse Regression method. However, it would be good to introduce the Classical Regression method alongside the Inverse. In addition, prediction bands for both methods should be introduced giving to the results the range of the confidence interval of the predictions.
Evaluation of F-Measure and Feature Analysis of C5.0 Implementation on Single Nucleotide Polymorphism Calling
Authors: Hasibuan Lailan Sahrina , Nabila Sita , Hudachair Nurul , Istiadi Muhammad Abrar
Published: October 2019

Data growing in molecular biology has increased rapidly since Next-Generation Sequencing (NGS) technology introduced in 2000, the latest technology used to sequence DNA with high throughput. Single Nucleotide Polymorphism (SNP) is a marker based on DNA which can be used to identify organism specifically. SNPs are usually exploited for optimizing parents selection in producing high-quality seed for plant breeding. This paper discusses SNP calling underlying NGS data of cultivated soybean (Glycine max [L]. Merr) using C5.0, an improved rule-based algorithm of C4.5. The evaluation illustrated that C5.0 is better than the other rule-based algorithm CART based on f-measure. The value of f-measure using C5.0 and CART are 0.63 and 0.58. Besides of that, C5.0 is robust for imbalanced training dataset up to 1:17 but it is suffer in large training dataset. C5.0’s performance may be increased by applying bagging or the other ensemble technique as improvement of CART by applying bagging in final decision. The other important thing is using appropriate features in representing SNP candidates. Based on information gain of C5.0, this paper recommends error probability, homopolymer left, mismatch alt and mean nearby qual as features for SNP calling.
Texture Features Extraction of Human Leather Ports Based on Histogram
Authors: Sinaga Anita Sindar
Published: October 2019

Skin problems general are distinguished on healthy and unhealthy skin. Based on the pores, unhealthy skin: dry, moist or oily skin. Skin problems are identified from the image capture results. Skin image is processed using histogram method which aim to get skin type pattern. The study used 7 images classified by skin type, determined histogram, then extracted with features of average intensity, contrast, slope, energy, entropy and subtlety. Specified skin type reference as a skin test comparator. The histogram-based skin feature feature aims to determine the pattern of pore classification of human skin. The results of the 1, 2, 3 leaf image testing were lean to normal skin (43%), 4, 5, tends to dry skin (29%), 6.7 tend to oily skin (29%). Percentage of feature-based extraction of histogram in image processing reaches 90-95%.
Prediction Of Amount Of Use Of Planning Family Contraception Equipment Using Monte Carlo Method (Case Study In Linggo Sari Baganti District)
Authors: Astia Rani Yunima , Santony Julius , Sumijan Sumijan
Published: October 2019

Family planning aims to minimize birth rates in Indonesia. To conduct socialization, it is carried out to existing fertile couples. Pus is a married couple whose wife is in the range of 15-49 years. Contraception itself consists of 2 periods, namely short and long. Where the pus can choose according to what they want, therefore there is often a lack of stock. Thus it is necessary to predict how many contraceptives are used with a method to be more efficient. The Monte Carlo method is used which is a numerical analysis method that involves a sample of random numbers. Where to use the previous year's data to get the predicted results of the next year in the form of numbers. After passing the simulation series the percentage results have been obtained with an average of over 80%.
Data Mining Optimization Using Sample Bootstrapping and Particle Swarm Optimization in the Credit Approval Classification
Authors: Agustian Andre Alvi , Bisri Achmad
Published: October 2019

Credit approval is a process carried out by the bank or credit provider company. Where the process is carried out based on credit requests and credit proposals from the borrower. Credit approval is often difficult for banks or credit providers. Where the number of requests and classifications must be made on various data submitted. This study aims to enable banks or credit card issuing companies to carry out credit approval processes effectively and accurately in determining the status of the submissions that have been made. This research uses data mining techniques. This study uses a Credit Approval dataset from UCI Machine Learning, where there is a class imbalance in the dataset. 14 attributes are used as system inputs. This study uses the C4.5 and Naive Bayes algorithms where optimization is needed using Sample Bootstrapping and Particle Swarm Optimization (PSO) in the algorithm so that the results of the research produce good accuracy and are included in the good classification. After using the optimization, it produces an accuracy rate of C4.5 which is initially 85.99% and the AUC value of 0.904 becomes 94.44% with the AUC value of 0.969 and Naive Bayes which initially has an accuracy value of 83.09% with an AUC value of 0.916 to 90 , 10% with an AUC value of 0.944.
Classification of Pineapple Fruit Comosus Merr (Nanas) Quality Using Learning Vector Quantization Method
Authors: Efendi Muhamad , Defit Sarjon , Nurcahyo Gunadi Widi
Published: October 2019

The demands of publics for these fruits Ananas Comosus Merr (Pineapple) became higher years to years because of the fruit has so many virtues for human healthy and the taste of this fruit is sweet and fresh. Therefore the pineapple farmers have to protect the quality and quantity of this plant in order to get high produce. This research help the pineapple farmers to classify to quality of pineapple fruits by using neural network with Learning Vector Quantization method which has 2 classes, such as: First quality (1st) and Second quality (2nd) quality. This method has 2 process they are : training process and testing process. To input data in the training and testing process are using uniformity, characteristic of varieties, the rate of aging, hardness, size, stem, crown, manure, destroyer, spoilage, rotten and the total solid content of the least was taken by observed the crop of pineapple farmers in the Teluk Batil village Sungai Apit district Siak Riau province. Learning Vector Quantization method automatically will classify the pineapple into their class. The result of the testing classification has gotten the accuracy 65.56% for the first (1st) quality and 34.44% for the second (2nd) quality. At the second testing has gotten 66.67% the accuracy for the first (1st) quality and 33.33% for the second (2nd) quality. At the third (3rd) testing has gotten 64.44% the accuracy for first (1st) quality and 35.56% for the second (2nd) quality.
Data Mining Predictive Modeling for Prediction of Gold Prices Based on Dollar Exchange Rates, Bi Rates and World Crude Oil Prices
Authors: Priyadi Iman , Santony Julius , Na'am Jufriadif
Published: October 2019

Gold is an investment instrument that is quite safe from inflationary attacks, and gold is one aspect of initiating investment. Can by buying gold in physical form and then selling when the price has risen high or by digitally investing gold. One of them is by trading gold online. To maximize the benefits of gold trading, a gold price prediction (XAUUSD) is needed for traders. This study aims to (1) Analyze various factors that influence the price of gold (2) Provide recommendations about the prediction of gold prices. Materials that will be used as objects of research to produce gold price predictions include historical XAUUSD (Gold) data itself, historical crude oil data, historical dollar data (USD IDR) and BI 7-Day Repo Rate (BI Rate). ), in producing the prediction of the gold price used Mining Predictive Modeling data using the linear regression function. The results to be achieved from this study is to provide accurate gold price predictions so that it can be used as a reference in making decisions to buy / sell positions in trading. The prediction of the XAUUSD gold price generated is expected to provide significant interest to the investment players (traders) in order to maximize the profit generated.From the results of the trading tests that have been carried out, the implementation of predictive modeling data mining using a linear regression function produces recommendations for gold price predictions (XAUUSD) with an accuracy of 85%.
Family Caregiver’s Quality of Life of Elderly Parent with Alzheimer’s Disease
Authors: Maitimoe Michael Dirk Roelof , Halim Magdalena S.
Published: October 2019

This research explores the relationship between burden of care, health perception, and demographic as aspects that affecting the quality of life of 50 family caregivers with the mean of age is 46.68 years old and SD = 12.97. Each subject has been given QoL-AD, HPQ, and ZBI-22, then being analyzed with Pearson Correlational Analysis and Multiple Regression Analysis with the stepwise method. The result showed that burden of care (r = - .454, p < .01), current health (r = .660, p < .01) and history of AD (r = .339, p < .05) significantly related to quality of life, while regression analysis shows that current health and AD history as a significant contributor (R2 = .496, p < .01) Furthermore, it is necessary to test the model with more diverse variables that significantly contributed to family caregivers’ quality of life.
An Investigation into the Effects of Martial Arts Training on Impulsive Consumer Behavior
Authors: Prasetyo Dimas Budi , Mari-Beffa Paloma
Published: October 2019

Consumer impulsiveness is an enticing topic regarding consumer behavior, and methods of avoiding such impulsiveness (through nurturing self-control) have been considered virtuous, mainly to achieve better long-term goals. Past studies show that self-control has been developed not only through a systematic theoretical framework but also neurologically. Martial arts (MA) training involves mind and body coordination, which is beneficial for nurturing concentration and self-control. The present study investigated the influence of martial arts training on individual capacity to avoid impulsive consumer behavior. Sixty-seven students joined in the study, in three different groups: (1) practitioners of martial arts (MA Group); (2) non-practitioners of martial arts (Non-MA Group); and (3) lapsed practitioner of martial arts (Lapsed-MA Group). The scale consisted of two separate subscales: (1) Consumer Impulsiveness Sub-scale (CIS); and (2) (Lack of) Premeditation Sub-scale. The study used some correlation methods, the ANCOVA method, and a hierarchical multiple linear regression analysis. Results showed that all three groups were prudent in their thinking processes and abilities to resist temptation. In the martial arts and ex-martial arts groups, the more frequent individual training (current training for the MA Group and in the past for the Lapsed MA Group), and the higher the ranks they achieved, significantly predicted their lower propensity towards impulsiveness in their consumer habits.
ANALISIS PENGARUH TINGKAT KORELASI ANTARA DUA KARAKTERISTIK KUALITAS TERHADAP KEPEKAAN GRAFIK PENGENDALI MULTIVARIATE T-HOTELLING DAN EWMA
Authors: Rega Kestrilia
Published: October 2019

Penelitian ini dilakukan untuk mengetahui pengaruh pergeseran tingkat korelasi antara dua karakteristik kualitas yang dikendalikan terhadap kepekaan grafik pengendali T-Hotelling dan MEWMA. Penelitian dilakukan dengan mensimulasikan keadaan pergeseran tingkat korelasi dari yang semula tidak berkorelasi menjadi berkorelasi sebesar 0.1, 0.2, 0.3, 0.4, 0.6, 0.7, 0.8 dan 0.9. Hasil yang diperoleh adalah bahwa untuk mendeteksi terjadinya perubahan tingkat korelasi antara dua karakteristik kualitas yang dikendalikan bersama, grafik pengendali T-Hotelling menunjukkan kepekaan yang lebih baik daripada grafik pengendali MEWMA berapapun tingkat korelasinya. Artinya grafik pengendali T-Hotelling selalu lebih cepat memberikan sinyal out-control jika pada keadaan sebenarnya telah terjadi pergeseran proses. Maka, untuk tujuan pengendalian kualitas produk yang membutuhkan informasi out-control sesegera mungkin  jika diduga pada keadaan sebenarnya dapat terjadi pergeseran tingkat korelasi, lebih baik menggunakan grafik pengendali T-Hotelling. Sedangkan untuk tujuan penelitian  lain yang membutuhkan presisi hasil yang tinggi penggunaan grafik pengendali MEWMA dapat dipertimbangkan.
Perbandingan Model Data Hilang dengan Model Least Median Square (LMS) pada Optimasi Respon Ganda menggunakan Metode Generalized Reduced Gradient (GRG) (Kasus Penggurdian Komposit Karbon)
Authors: Akbar Muhammad Sjahid , Rega P Kestrilia
Published: October 2019

Epoxy drillings have consequences the chisel will worn down and drilling result vary greatly. This research purpose is to minimize the chisel wearing out and drilling result deviation with generalized reduce gradient method (GRG). advantage of the method can to look for weighted from both response. This method Applied to outlier data for the chisel wearing out. Research result are more take note of the chisel wearing out than drilling result deviation and optimum condition to machine speed is 715,5 rpm, scrape speed is 90 mm/min, chisel angel is 73,8o with the chisel wearing out is 0,3253 mm and drilling result deviation 5,3720 micron.
EFEKTIVITAS PERASAN DAUN Lantana camara Linn. TERHADAP MORTALITAS LARVA Plutella maculipennis Curt.
Authors: Haryono Tjipto
Published: October 2019

Larva Plutella maculipennis Curt. is pest capable to destroying cabbage leaf. To overcome this pest applied extract of leaf Lantana canmara Linn. what having contents of latadene-A available for mucosa irritation at gastrointestinal system of insect. This research aim to know influence of extract of leaf Lantana camara Linn. To larva mortality Plutella maculipennis Curt. and look for alternative of material replacing insecticide kimiawi for controling larva Plutella maculipennis Curt.

This research including research of eksperimental with Completely Randomized Design (CRD) apply treatment of concentration of extract of leaf Lantana camara Linn. different that is 0%; 0,2%; 0,4%; 0,6%; 0,8% and 1%, done by is repetition counted 4 times; rill. Parameter which checked in the form of level of larva mortality Plutella maculipennis Curt. later on analysed to apply probit analysis.

This research conclude that extract of leaf Lantana camara Linn. with concentration of 1% can result mortality Plutella maculipennis Curt. equal to 75% ( highest). While extract of leaf Lantana camara Linn. with concentration of 0,2% result mortality Plutella maculipennis Curt. equal to 15% ( low).
PENJADWALAN PRODUKSI DI CV. JATI AGUNG FURNITURE
Authors: Susanti Herdiana Dyah
Published: October 2019

This research is done for particular company in furniture scope which is all of order produced by job order system. For the time being the company oftenly couldn’t fulfil the order from the consument on time. It was because the company scheduled the products based on the biggest product volume if the order came on the same day without paid any attention to due date which are agreed both by consument and the company. This research is done by improving the set up method with SMED method, finishing time model, a better scheduled with EDD and SPT method for regular job and MWKR rule. The result showed that by scheduling proposal was gotten of decreasing mean tardiness from 0,667 the postpone day (delayed day) become no delayed.