bluuebunny/crossref_metadata_2025 huggingface dataset:
SETINT AI ARTIFICIAL INTELLIGENCE HOSPITAL PROJECT
Authors: SEZER Sezgin , Demir Ayça Nur
Published: May 2022

In2019,westartedourcorporateactivitiesatDüzceUniversityTechnopark.WeareengagedinR&Dstudiesinthefieldofhealthsector.Themainaimofourorganizationistoincreasetherecognitionlevelofourcountryinthefieldofartificialintelligenceinhealthinthecountryandabroadandtobethefirstinthepositionofartificialintelligencehospital.Asaresultofourstudiesandactivities,weincludeourvaluableprofessorsandcolleagueswithinourorganization.Inaddition,wecooperatewithvariousinstitutionsandorganizationsandtakenewstepswiththem.Wehavereachedaconsensusoncooperationnotonlywithdomesticemployees,institutionsandorganizations, but also with many countries abroad.
Differential Gene Expression of Nystagmus-Associated Genes in Chronic Traumatic Encephalopathy, Parkinson's Disease, and Alzheimer's Disease
Authors: De Los Reyes Francia Victoria
Published: May 2022

Objectives: The research aimed to determine whether the genes that presented with nystagmus as part of their clinical presentation were differentially expressed in the brains of patients with Parkinson’s Disease (PD), Chronic Traumatic Encephalopathy (CTE), and Alzheimer’s Disease (AD).

Methodology: The data was derived from the available NCBI SRA datasets that allowed public domain use. The RNA sequence from the brain samples of the patients underwent differential expression analysis using the web-based platform Galaxy and R version 4.1.0 with R Studio.

Results: There were only 19 genes out of the 28,395 retrieved genes in the patient groups and the control group that had significant under-expression in the patient group compared to controls (p<0.001). The genes that were identified can be divided into those involved in protein synthesis, cell cycle regulation, gap junction formation, transcription regulation, signal transduction, and synaptic function.

Conclusion: Performing differential gene expression studies in the brain samples of post-mortem cases illustrate how autopsy pathology and neuroinformatics can elucidate the common genomic changes and molecular mechanisms that can present across different diseases which may have future significance in the field of both neuro- and ophthalmic pathology.
The Challenges Faced by Entrepreneurs While Starting and Operating Business in a New Country
Authors: Vafin Aidar
Published: May 2022

Starting and running a business is difficult in any climate, but it is significantly more difficult in a new country. This research makes a contribution to the entrepreneurship literature by shedding light on the most common barriers encountered by most entrepreneurs during the seed and growth stages of doing business in a new foreign country. When launching a new company in a new nation, the first hurdle is acquiring funds for the enterprise due to short or poor credit history. Individuals with insufficient native language competence may struggle to communicate with potential clients and suppliers, as well as understand the regulation of the new country, and gain access to local entrepreneurial institutions. Additionally, many newcomers struggle to gather appropriate knowledge about the market conditions, current needs, the kind of business, and the market dynamics prevalent in the new country. Additionally, the majority of new businesses started by newly arrived company owners are small, making it more difficult for them to hire experienced, qualified, and skilled native human resources to compete with localcompetitors. People are going to continue to migrate around the globe, and immigrants will bring new ideas and commercial endeavors with them. This study recommends that the government and other agencies must ensure that immigrants have access to services that meet their specific requirements and help them integrate into the local business community.
Comparative Analysis on the Variability of Evapoteanspiration and Windspeed in Enugu State
Authors: Banlack Jude
Published: May 2022

This study investigated the variability of evapotranspiration and wind speed in Enugu State. Daily maximum and minimum air temperature, maximum and minimum humidity, solar radiation and evapotranspiration for 20 years (1991 – 2010) was obtained from the International Institute for Tropical Agriculture, Ibadan (IITA). The Priestley and Taylor method was used to compute evapotranspiration in Enugu and the One Way Analysis of Variance (ANOVA) was used to determine if there is a significant difference between the mean monthly evapotranspiration. The results show that the lowest evapotranspiration (3.89mm/day) was obtained in rainy season (July) due to high humidity of the air and the presence of clouds, while highest evapotranspiration (4.36mm/day) was obtained in dry season due to the dryness of air. The One Way Analysis of Variance (ANOVA) revealed that there is a significant difference between the mean evapotranspiration across the months. Among climatic factors affecting evapotranspiration, it was observed that wind speed displayed relatively small variations in it’s trend over the period of this study and is not in line with variations of evapotranspiration. It is herein recommended that other methods be used to analyze the variability in evapotranspiration in Enugu and compared with the method used in this study.
C-Reactive Protein to Albumin Ratio and Albumin to Fibrinogen Ratio in Rheumatoid Arthritis Patients
Authors: Amira Elsabagh Abdou , Heba Abd-Elwahab Selim , Amany Mohamed Mohyeldin , Marwa Ahmed Hany
Published: May 2022

Objective: the albumin to fibrinogen ratio (AFR) and the C-reactive protein (CRP) to albumin ratio (CAR) have been proposed as markers of systemic inflammation. The goal of this study was to differentiate rheumatoid arthritis (RA) patients from healthy people and to study the association between AFR/CAR and DAS28 in RA.

Patients and methods. A case control study including 30 RA patients and 30 healthy controls was performed. Fibrinogen, albumin, CRP and erythrocyte sedimentation rate (ESR) were measured. We calculated CAR and AFR in each group and compared them. Correlations of AFR, and CAR with disease activity were examined. Receiver operation characteristic (ROC) curves of AFR and CAR were also used to detect cutoffs for disease activity assessment.

Results and discussion. CAR was higher while AFR was lower in RA patients than in control group. ROC curve analyses showed that CAR can be used to detect disease activity of RA at cut off 2.66 with sensitivity 81.3% and specificity 64.3% with an area under the curve (AUC) 0.78. So, CAR was a fair parameter to discriminate disease activity among RA patients. AFR has AUC 0.62, sensitivity 87.5% and specificity 42.9% at cutoff value 5.96. So, in our group AFR was a poor indicator to discriminate disease activity among RA patients.

Conclusion. AFR and CAR have been recently proposed as inflammatory markers for assessment of disease activity in RA. AFR and CAR are simple, and inexpensive biomarkers, they also can be rapidly evaluated. CAR was found to be a fair parameter to depict disease activity in RA patients. AFR poorly depicted RA activity.
Results of an open multicenter non-interventional study of clinical efficacy and tolerability of etoricoxib in osteoarthritis and nonspecific back pain with additional evaluation of the effect of the drug on the «central» manifestations of pain
Authors: Karateev A. E. , Polishchuk E. Yu. , Filatova E. S. , Amirdzhanova V. N. , Nesterenko V. A. , Potapova A. S. , Glukhova S. I. , Lila A. M. , Sarapulova A. V. , Mukhin A. A. , Lyusina O. S. , Levasheva L. A. , Kryukova E. V. , Klein D. K. , Kichai N. V. , Kabalyk M. A. , Dobrokhotova N. E. , Grabovetskaya Yu. Yu. , Blagodareva L. A. , Zonova E. V. , Zwinger S. M. , Popov P. P.
Published: May 2022

The formation of chronic musculoskeletal pain (MSP) is a multifactorial process, in its pathogenesis mechanism of central sensitization (CS) plays an important role.

Objective: to evaluate the effectiveness of etoricoxib at a dose of 60 mg per day in diseases accompanied by moderate/severe chronic MPS, with an additional analysis of the effect of this drug on the manifestations of CS.

Patients and methods. An open observational study, 790 patients (71.6% women, mean age 54.5±13.0 years) with osteoarthritis and chronic nonspecific back pain received etoricoxib 60 mg/day for 2 weeks. The dynamics of pain, dysfunction, fatigue, sleep disturbances, general health assessment (GHA) on a numerical rating scale (NRS 0–10), as well as signs of CS according to part A of the CSI questionnaire were assessed.

Results and discussion. After 2 weeks, the intensity of pain during movement, at rest and at night decreased on average by 58.8±24.1, 69.7±32.6 and 70.1±32.8% respectively; functional insufficiency by 58.2±22.5%, fatigue by 52.2±25.8%, GHA by 50.0±22.6%, sleep improvement by 54.3±25.8% was observed (p<0.001 for all parameters). There was a decrease in the CSI value by an average of 33.1±14.5% (p<0.001), as well as a decrease in the number of patients with highly probable CS (CSI ≥40) from 35.3 to 10.3% (p<0.001). No serious drug-related complications were recorded. The overall frequency of adverse reactions was 5.9%, with dyspepsia and hypertension being the most common.

Conclusion. Etoricoxib is an effective and relatively safe treatment for chronic MSP. It reduces the severity of CS, one of the central mechanisms of the pathogenesis of chronic MSP.
Use of telemedicine consultations in rheumatology during the COVID-19 pandemic
Authors: Teplyakova O. V. , Morozova A. A.
Published: May 2022

Objective: to study the practice of organizing and conducting telemedicine consultations (TMC) of a rheumatological profile, their effectiveness and the main problems that arise during the implementation of this technique.

Patients and methods. From June 2020 to December 2021, 102 rheumatological TMCs were performed at the «New Hospital» Medical Association in Yekaterinburg. Patients aged 18–82 years applied for TMC after a face-to-face examination and for the purpose of «pre-consultation». TMC included the following steps: familiarizing the doctor with previous medical reports and the results of examinations; video conference; preparation of final medical report. The Aibolit service and the «Medkarta» platform were used. After TMC, a survey of doctors and patients was conducted to identify the positive and negative aspects of this technique.

Results and discussion. Most of the patients who applied for TMC suffered from diseases that required regular monitoring of disease activity (rheumatoid arthritis, psoriatic arthritis, systemic connective tissue diseases), as well as fibromyalgia. Leading reasons for seeking medical advice: exacerbation of the disease or new symptoms onset, the need for laboratory and instrumental monitoring and correction of therapy. The vast majority of patients (90.2%) received answers to all questions and 9.8% – to most of the questions. Doctors had technical problems in 34 (33.3%) cases, including 11 (10.8%) cases when they had to switch to another method of communication.

Conclusion. TMK is a promising technique that can be useful and convenient for patients both now, during the COVID-19 pandemic, and in the future. Its main unresolved problems are the recognition of parity between TMK and face-to-face consultations and the improvement of technical conditions.
Organ changes after SARS-CoV-2 infection in a patient with systemic sclerosis according to autopsy
Authors: Vorobeva O. V. , Romanova L. P.
Published: May 2022

The article presents a description of a clinical case with a fatal outcome due to SARS-CoV-2 coronavirus-induced bilateral viral pneumonia with areas of pneumofibrosis, complicated by acute respiratory failure. The presence of systemic sclerosis in this patient aggravated the course of the disease and became one of the causes of death. Autopsy revealed signs of bilateral pneumonia with lesions in both lungs and areas of pneumofibrosis.

Histological examination revealed alveoli with rupture of interalveolar septa, areas of atelectasis, serous-purulent exudate with desquamated alveolocytes, places with organization of exudate, zones of pneumofibrosis. Scleroderma cardiosclerosis, linear necrosis of cardiomyocytes were present in the heart. There were signs of multiple organ failure – pulmonary edema, cerebral edema.
Vaccination in persons with systemic lupus erythematosus: the current state of the problem
Authors: Belov B. S. , Popkova T. V. , Tarasova G. M. , Muravieva N. V.
Published: May 2022

Vaccination plays an important role in the prevention of infectious diseases in patients with immunoinflammatory diseases. When vaccinating patients with systemic lupus erythematosus (SLE), as with other immunoinflammatory rheumatic diseases, its safety is of great importance, including mitigating the risks of the primary disease or the development of new autoimmune phenomena. Many practitioners continue to consider autoimmune diseases as a contraindication for vaccination due to the perceived possibility of their exacerbation and reduced vaccine effectiveness during active immunosuppressive therapy.

The lecture presents current data on the immunogenicity, efficacy and safety of vaccines against a number of infections caused by influenza viruses, hepatitis B, Herpes zoster, human papilloma viruses, COVID-19 and pneumococcus in patients with SLE. It has been shown that the benefits of vaccination in patients with SLE significantly outweigh the risk of adverse events or exacerbations of the disease. At the same time, it was noted that the problem of vaccination of such patients requires further study.
Significance of hyperferritinemia as a diagnostic and prognostic biomarker
Authors: Kaleda M. I. , Fedorov E. S.
Published: May 2022

Ferritin is a complex protein composite (iron protein) that plays the role of the main intracellular iron depot in humans and animals, consisting of the protein apoferritin and the ferric atom in the composition of phosphate hydroxide. The reference value of ferritin in women is 200 μg/l, in men – 300 μg/l. Ferritin is a marker of total body iron stores, and low levels are specific for iron deficiency. Ferritin is also involved in immune processes and has both pro-inflammatory and immunosuppressive activity. Hyperferritinemia is a nonspecific symptom that occurs in a number of immunoinflammatory, infectious diseases, as well as during body iron stores overload. Hyperferritinemia is a criterion sign of macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis, systemic lupus erythematosus and Kawasaki disease, as well as a predictive biomarker of adult-onset Still's disease. High ferritin levels occur in catastrophic antiphospholipid syndrome, as well as in infectious pathologies such as septic shock and COVID-19, including multisystem inflammatory syndrome associated with COVID-19. Ferritin concentration is an important parameter for assessing the activity and prognosis of the disease, which allows a rational approach to the choice of therapy in these patients.
The problem of long-term pain control in chronic rheumatic diseases
Authors: Polishchuk E. Yu. , Karateev A. E.
Published: May 2022

Pain is one of the main symptoms and the most distressing manifestation of rheumatic diseases (RD). Currently, non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for the symptomatic treatment of RD in real clinical practice, but the effectiveness and tolerability of their longterm use remain insufficiently studied. Many patients with RD require long-term use of NSAIDs. In this case, the presence of comorbid pathology and risk factors for the development of drug complications should be taken into consideration, so the choice of NSAIDs should be based primarily on considerations of patient safety. Aceclofenac (Aertal®) has a pronounced analgesic potential and a good safety profile, which allows us to recommend it for long-term use.
Analysis of the mechanisms of development of neurorheumatological consequences of COVID-19 and the possibility of their pharmacological correction
Authors: Sarvilina I. V. , Lila A. M. , Gromova O. A. , Torshin I. Yu. , Shavlovskaya O. A. , Taskina E. A.
Published: May 2022

We present the review of clinical and experimental studies on the pathogenesis of neurorheumatological complications (NRC) in COVID-19. The influence of systemic hyperinflammation caused by impaired innate immunity on the functioning of the neurovascular endothelium and the bloodbrain barrier, activation of signaling pathways of innate immunity and parainfectious autoimmunity in the central nervous system were analyzed.

Hyperinflammation has been shown to contribute to the development of NRC in COVID-19. The potential therapeutic efficacy of drugs, including those based on chondroitin sulfate, which can be used for the prevention and treatment of NRC in COVID-19, is considered.
Diagnostic value of cone beam computed tomography in complex and compound odontomas: a systematic review and open classification matrix
Authors: Dubron Kathia , Gurniak Anna , Gurniak Eliza , Politis Constantinus , Olszewski Raphael
Published: May 2022

Objective: Firstly, this review aims to analyse the recent literature about three-dimensional (3D) diagnostic imaging in complex and compound odontomas and compare it to two-dimensional (2D) imaging. Panoramic radiographs help to

evaluate the vertical position of odontomas, and occlusal radiographs are used to evaluate the proximity to adjacent teeth. However, cone beam computed tomography (CBCT) can offer volumetric images, and therefore, a more accurate three-dimensional analysis. Secondly, this research aims to construct an open classification matrix for complex and compound odontomas for dentomaxillofacial CBCT radiology protocols based on a systematic literature review.

Material and methods: Two systematic literature searches were conducted in PubMed (Medline), on 2 February 2022 concerning classification systems, and on 5 February 2022 concerning CBCT images.

Results: In total, these searches revealed 391 papers by reviewing the databases mentioned above. Six articles were selected for inclusion on classification of odontomas and 13 articles were found on CBCT imaging. Consequently, the

construction of an open classification matrix for compound and complex odontomas for dentomaxillofacial CBCT radiology protocols was performed using these 19 articles.

Conclusions: CBCT offers a more precise position and accurate diagnosis of complex and compound odontomas compared to 2D imaging. Consequently, it enhances the detailed view of the site (multiple or unique), location (intraosseous, partially or completely extragnathic), size, extension (bony expansion, thinning or perforation cortical bone), density and type (denticulo type, particle type, denticulo-particle type, denticulo-amorphous type, amorphous tissue), relationship (with the crown or root of the definitive tooth), adjacent teeth resorption (deciduous or definitive), adjacent teeth (retention or impaction), and distance with adjacent structures (inferior alveolar nerve, sinus maxillaris), as well as adequate surgical planning. Moreover, this research presents an open classification matrix for the most complete description of compound and complex odontomas when analysing CBCT imaging.
Integrationsregime in der Arbeitswelt
Authors: Pierdicca Marika
Published: May 2022

Marika Pierdiccas Promotionsschrift liefert eine Ethnographie migrantischer Selbstständigkeit in Norditalien und zeigt die Verknüpfung zwischen einer zunehmenden Neoliberalisierung der Arbeit und Vorstellungen von »Integration« auf. Die Arbeit stellt Integration als affirmatives Konzept infrage und problematisiert strukturelle Formen von differentieller Inklusion, Rassifizierung und Ethnisierung heutiger Arbeitsverhältnisse. Eine genealogische Rekonstruktion italienischer Migrationspolitiken verdeutlicht, wie das »Integrationsregime« zugleich als Selektierungsmanagement und als Grenzpolitik agiert. Vor dem Hintergrund eines Verständnisses von Selbstständigkeit als gesamtem Lebensentwurf, vollzieht Pierdicca eine biopolitische Analyse von Arbeitsnarrativen und -erfahrungen der Protagonist_innen im Feld. Ihre Forschung beschäftigt sich mit kapitalismuskritischen Ansätzen zu affektiver Arbeit, betrachtet das Integrationsregime als Labor neoliberaler Subjektivierung und arbeitet dabei spezifische Formen von Arbeitsausbeutung heraus.
Pengaruh Buangan Limbah Tambak Terhadap Kelimpahan Perition pada Daun Lamun Enhalus acoroides di Teluk Awur dan Pulau Panjang, Jepara
Authors: Asih Melinda Sri , Widianingsih Widianingsih , Riniatsih Ita
Published: May 2022

Perifiton merupakan sekelompok organisme yang hidup menempel pada permukaan tumbuhan air yang terendam, tidak menembus substrat, diam atau bergerak di permukaan substrat. Perifiton yang menempel pada daun lamun berperan sebagai faktor penunjang produktivitas primer pada ekosistem lamun, namun apabila kelimpahan perifiton terus meningkat maka akan menghambat pertumbuhan lamun karena lamun akan tertekan dan tidak dapat melakukan fotosintesis dengan baik. Penelitian ini bertujuan untuk mengetahui perbedaan pengaruh buangan limbah tambak terhadap kelimpahan perifiton yang menempel pada daun lamun Enhalus acoroides di Perairan Pantai Teluk Awur dan yang tidak ada buangan limbah tambak di Pulau Panjang, Jepara. Penelitian ini menggunakan Metode Line Transek Kuadran. Pengambilan sampel perifiton dilakukan dengan menggunakan metode sapuan dan pengamatan perifiton dilakukan dengan menggunakan metode sensus dengan bantuan Sedgwick-Rafter. Kelimpahan perifiton di Stasiun 1 dan Stasiun 2 berturut-turut 127,51 ind/cm2 dan 86,25 ind/cm2. Kelimpahan tertinggi ditemukan pada Stasiun 1 karena memiliki pengaruh buangan limbah tambak udang yang ditemukan 3 kelas dan terdiri dari 18 genus, sedangkan pada Stasiun 2 ditemukan 2 kelas yang terdiri dari 13 genus. Kelas perifiton yang mendominasi adalah Bacillariophyceae karena kelas ini dapat bertahan dalam kondisi lingkungan yang tidak stabil.  Periphyton is a group of organisms that live attached to the surface of submerged aquatic plants, do not penetrate the substrate, remain stationary or move on the surface of the substrate. Periphyton attached to seagrass leaves acts as a primary productivity supporting factor in the seagrass ecosystem, but if the abundance of periphyton continues to increase it will inhibit seagrass growth because the seagrass will be depressed and unable to perform photosynthesis properly. This study aims to determine the effect of pond waste disposal on the abundance of Enhalus acoroides seagrass periphyton in the waters of Teluk Awur and Panjang Islands, Jepara. This study used the Quadrant Line Transect Method. Periphyton sampling was carried out using the sweeping method and periphyton observations were carried out using the census method with the aid of a Sedgwick-Rafter. The abundance of periphyton at Station 1 and Station 2 is 127.51ind / cm2 and 86.25 ind / cm2, respectively. The highest abundance was found at Station 1 because it influenced shrimp pond waste disposal which was found in 3 classes consisting of 16 genera. The dominating class of periphyton is Bacillariophyceae because this class can survive in unstable environmental conditions.
Optimasi Substrat Dan Pemilihan Co-Substrat Media Kultur Yang Sesuai Terhadap Pertumbuhan Dan Aktivitas Protease Ektraseluler Bakteri Bacillus Firmus Dari Perairan Nusa Lembongan Bali, Indonesia
Authors: Zainuddin Muhammad , Pringgenies Delianis , Radjasa Ocky Karna , Haeruddin Haeruddin , Sabdaningsih Aninditia , Herawati Vivi Endar
Published: May 2022

Udang merupakan sumber protein hewani yang banyak diminati masyarakat karena citarasa enak dan bergizi. Udang merupakan komoditas perikanan ekspor. Upaya pemenuhan kebutuhan ekspor udang saat ini telah dilakukan budidaya intensif. Budidaya intensif telah terjadi pemberian pakan yang berlebih sehingga terbentuk limbah organik di dasar tambak. Limbah pakan mengakibatkan terbentuknya senyawa nitrit dan amoniak yang toksik bagi udang. Komponen utama limbah ini adalah protein. Protein harus di dekomposisi menjadi asam amino oleh bakteri proteolitik. Salah satu bakteri yang memiliki aktivitas proteolitik adalah bakteri Bacillus Firmus dari simbion sponge Chalinula Pseudomolitba. Tujuan penelitian adalah melakukan optimasi substrat dan pemilihan co-substrat media kultur yang sesuai terhadap pertumbuhan dan aktivitas protease ektraseluler Bacillus Firmus. Penelitian menggunakan metode eksperimen laboratoris. Penelitian terdiri dari uji optimasi substrat, pemilihan Co-substrat C dan N. Hasil penelitian menunjukkan bahwa bakteri Bacillus firmus memiliki laju pertumbuah dan aktivitas protease terbaik pada media kultur dengan subtrat susu skim 1% dengan nilai 0,110 c/jamdan 12,566 c IU/ml. Sumber C terbaik adalah glukosa dengan nilai 0,124 c/jamdan 16,094 cIU/ml. Sumber N terbaik adalah amonium nitrat dengan nilai sebesar 0,137 c/jamdan 19,046 c IU/ml. Shrimp is a source of protein and have good taste. Shrimp is an export commodity. Shrimp cultivation is developing to be intensive. Intensive cultivation uses large amounts of feed. not all of the feed is eaten. leftover feed becomes waste. Feed waste produces nitrite and ammonia. Ammonia is toxic. Feed waste must be cleaned. Decomposition process by proteolytic bacteria. Bacillus Firmus is a proteolytic bacterium from the symbiont sponge Chalinula Pseudomolitba. The research aims to optimize the substrate and select the co-substrate. The study used a laboratory experimental method. The research consisted of a substrate optimization test, selection of Co-substrate C and N. The results showed that Bacillus Firmus had the best growth rate and protease activity on 1% skimmed milk substrate with values of 0.110 c/hour and 12,566 c IU/ml. The best source of C is glucose with a value of 0.124 c/hour and 16,094 c IU/ml. The best source of N as ammonium nitrate with values of 0.137 c/hour and 19,046 c IU/ml.
Penggunaan Citra Satelit Sentinel-2A untuk Mengevaluasi Perubahan Garis Pantai Semarang Jawa Tengah
Authors: Zaidan Rafif Rizki , Suryono Chrisna Adhi , Pratikto Ibnu
Published: May 2022

Kota Semarang merupakan kota pesisir yang rentan akan pengaruh dari alam dengan kondisi fisik yang berpasir dan berlumpur, topografi yang landai dan adanya banyak kegiatan manusia. Hal tersebut membuat Kota Semarang mengalami perubahan garis pantai yang dinamis dari tahun ke tahun, oleh karena itu perlu dilakukan penelitian secara kontinu untuk memantau perubahan garis pantai yang terjadi. Tujuan dari penelitian ini adalah mengetahui perubahan garis pantai yang terjadi di Kota Semarang menggunakan citra satelit Sentinel-2A. Metode dalam penelitian ini adalah dengan mengaplikasikan penginderaan jauh yang dilanjutkan dengan perhitungan statistik Digital Shoreline Analysis System (DSAS) pada aplikasi penginderaan jauh dan pengolahan data sekunder angin, gelombang dan arus. Hasil penelitian menunjukkan bahwa dalam kurun waktu 2016-2021, garis pantai Kota Semarang mengalami perubahan berupa abrasi seluas 186.34 ha dan akresi sebesar 43.62 ha, dimana abrasi mendominasi perubahan dengan persentase 81%, sementara akresi yang terjadi hanya 19%. Rata-rata jarak dan laju perubahan yang terjadi masing-masing sebesar -32.78 meter dan -6.47 meter/tahun yang menunjukkan perubahan garis pantai berupa abrasi. Secara keseluruhan, pada periode 2016 hingga 2021 Kota Semarang cenderung mengalami pengurangan daratan atau abrasi. The city of Semarang is a coastal city that is vulnerable to the influence of nature with physical conditions of sandy and muddy beach, low topography and the presence of many human activities. This made the city of Semarang experience dynamic coastline changes from year to year, therefore it is necessary to conduct continuous research to monitor changes in coastline that occur. The purpose of this study was to determine changes in the coastline that occurred in the city of Semarang using Sentinel-2A satellite imagery. The method in this study is applying satellite imagery from remote sensing technology followed by statistical calculations using Digital Shoreline Analysis System (DSAS) on remote sensing application and the processing of wind, wave and current as secondary data. The results showed that in the 2016-2021 period, the coastline of Semarang City experienced changes in the form of 186.34 ha of abrasion and 43.62 ha of accretion, where abrasion dominated the change with a percentage of 81%, with accretion of only 19%. The average distance and rate of change that occur are -32.78 meters and -6.47 meters/year, respectively, indicating changes in the coastline in the form of abrasion. Overall, in the period 2016 to 2021, Semarang City tends to experience land reduction or abrasion.
Logam Berat pada Beberapa Jenis Ikan di Sekitar Perairan Tanjung Api-Api Sumatera Selatan
Authors: Eka Putri Wike Ayu , Agustriani Fitri , Fauziyah Fauziyah , Purwiyanto Anna Ida Sunaryo , Angraini Novi , Ardila Dika
Published: May 2022

Perairan Tanjung Api-Api merupakan kawasan yang banyak digunakan dalam aktivitas perikanan di wilayah Kabupaten Banyuasin, Sumatera Selatan. Selan itu Perairan Tanjung Api-Api juga dimanfaatkan sebagai areal pemukiman, transportasi dan direncanakan sebagai area pelabuhan kedepannya. Kondisi ini tentu dapat berpotensi meningkatkan masukan bahan pencemar seperti logam berat ke perairan tersebut. Tujuan penelitian adalah untuk menentukan konsentrasi logam Pb dan Cu serta menganalisis kelayakan pangan pada daging ikan yang tertangkap di perairan Tanjung Api-Api Sumatera Selatan. Terdapat 3 jenis ikan yang dominan tertangkap yaitu ikan senangin (Eleutheronema tetradactylum), puput (Ilisha elongata) dan bawal putih (Pampus argenteus). Ketiga ikan tersebut diambil bagian dagingnya dan dianalisis kandungan logam berat Pb dan Cu mengacu pada SNI 2354.5 : 2011. Hasil penelitian menunjukkan konsentrasi Pb pada ketiga jenis ikan berkisar antara 0,89-5,89 mg/kg (rata-rata 2,28-3,28 mg/kg) dan konsentrasi Cu berkisar antara 0,06 – 1,28 mg/kg (rata-rata 0,20 – 0,78 mg/kg). Berdasarkan baku mutu BPOM, SNI 7387:2009 dan FAO (1983) akumulasi Pb telah melebihi batas yang diperkenankan. Sedangkan akumulasi Cu berdasarkan baku mutu P FAO (1983) dan Soegianto (2008) masih dibawah batas yang diperkenankan.  Tanjung Api-Api waters is an area that widely used as a fishery activity in the Banyuasin Regency, South Sumatera. Tanjung Api-Api waters are also used as residential area, transportation and as a port area. This condition can increase the input of pollutants such as heavy metals. The purpose of this study was to determine the Pb and Cu metal concentrations in fish from Tanjung Api-Api waters, South Sumatera. There are 3 types of fish that are predominantly caught, Eleutheronema tetradactylum, Ilisha elongata and Pampus argenteus. The three fish were taken part of the meat and analyzed the content of heavy metals Pb and Cu referring to SNI 2354.5: 2011. This reseach show that Pb concentrations in all types fish ranged from 0.89 to 5.89 mg/kg (average 2.28-3.28 mg/kg) and Cu concentrations ranged from 0.06 - 1.28 mg/kg (average 0.20 - 0.78 mg/kg). Based on National Food and Drug Agency, SNI 7387: 2009 and FAO (1983) the accumulation of Pb were exceeded specified quality standards. Whereas Cu accumulation based on FAO (1983) and Soegianto (2008) are still below the allowed limits.
Sebaran Ikan Sidat (Ikan Katadromus) di Perairan Sungai Lorok Ngadirojo, Kabupaten Pacitan, Jawa Timur
Authors: Romadhi Muhammad Arif , Indarjo Agus , Suryono Chrisna Adhi
Published: May 2022

Ikan sidat Anguilla sp. merupakan kategori ikan yang bermigrasi secara katadromous, artinya ikan sidat mengawali hidup di laut yang bermigrasi ke perairan tawar untuk tumbuh menjadi sidat dewasa dan kembali ke laut untuk melakukan pemijahan (spawning migration). Penelitian ini bertujuan untuk melakukan klasifikasi jenis dan ukuran panjang kelompok sebaran ikan Sidat di Perairan Ngadirojo, Kabupaten Pacitan. Penentuan kelompok menggunakan metode morfometrik dan jenis sampel menggunakan A/D%. Hasil menunjukkan distribusi ikan sidat yang ditemukan di Muara Sungai Lorok terdapat dua spesies, yaitu Anguilla bicolor dan Anguilla marmorata. Frekuensi ukuran panjang distribusi benih ikan sidat (glass eel) kisaran ukuran panjang total 4,8 cm hingga 7,56 cm dengan rata – rata 6,0 ± 0,9 hingga dan Sedangkan ukuran panjang distribusi sidat muda (yellow eel) kisaran ukuran panjang 37,98 cm hingga 48,0 cm dengan rata – rata 43,2 ± 3,1. Analisis uji beda mendapatkan nilai signifikansi (p= 0,00 < 0,01) maka adanya perbedaan ukuran panjang antara stasiun di aliran SungaI Lorok. Freswater eels Anguilla sp. is a category of fish that cathadromous migrate, that eel fish begin to live in the sea that migrates to fresh waters to grow into adult eels and returns to the sea to spawning migration. This study aims to classify the type and size of the length of the Eel fish distribution group in Ngadirojo Waters, Pacitan Regency. This study aims to classify the type and size of the length of the Eel fish distribution group in Ngadirojo Waters, Pacitan Regency. Group determination using morphometric methods and sample types using A/D%. The results showed that the distribution of eel fish found in the Lorok River was two species, namely Anguilla bicolor and Anguilla marmorata. The frequency of the length distribution of glass eel seeds (glass eel) ranges in total length from 4.8 cm to 7.56 cm with an average of 6.0 ± 0.9 to and. 37.98 cm to 48.0 cm with an average of 43.2 ± 3.1. The analysis of the difference test got a significance value of (p= 0,00 < 0,01), so there is a difference in length between stations in the Lorok River flow.
Kandungan Lutein Mikroalga Chlorella vulgaris dengan Salinitas Berbeda pada Media Kultur
Authors: Lasmarito Theresia Claudia , Widianingsih Widianingsih , Endrawati Hadi
Published: May 2022

Chlorella vulgaris merupakan mikroalga yang tergolong dalam alga hijau (chlorophyta). C. vulgaris mengandung pigmen karotenoid yang hampir sebagian besar terdiri dari lutein. Hal ini membuat C. vulgaris memiliki keunggulan dibandingkan dengan jenis mikroalga lain. Lutein memiliki manfaat sebagai antioksidan untuk melawan radikal bebas pada mata. Salah satu parameter lingkungan yang mempengaruhi jumlah kandungan lutein adalah salinitas. Penelitian ini bertujuan untuk mengetahui salinitas terbaik guna mengoptimalkan pertumbuhan dan produksi pigmen lutein pada C. vulgaris. Metode yang digunakan adalah eksperimen laboratorium dengan menggunakan Rancangan Acak Lengkap. Mikroalga C. vulgaris di kultivasi dengan tiga taraf perlakuan salinitas yang berbeda yaitu 20, 25, 35 dan 30 ppt (kontrol) dengan tiga ulangan. Pertumbuhan C. vulgaris diamati selama 8 x 24 jam kemudian dipanen untuk perhitungan biomassanya. Biomassa basah hasil kultivasi diekstraksi menggunakan pelarut aseton PA. Ekstrak aseton C. vulgaris kemudian dianalisis kandungan pigmen luteinnya secara spektrofotometri. Kandungan pigmen lutein C. vulgaris tertinggi diproduksi pada salinitas 35 ppt yakni 0.011363 µg/g. Berdasarkan hasil penelitian dapat disimpulkan bahwa perlakuan salinitas berpengaruh secara signifikan terhadap kandungan pigmen lutein C. vulgaris. Chlorella vulgaris is a microalga belonging to the green algae (chlorophyta). C. vulgaris contains carotenoid pigments which consist mostly of lutein. This makes C. vulgaris has advantages compared to other types of microalgae. Lutein has benefits as an antioxidant to fight free radicals in the eyes. One of the environmental parameters that affect the amount of lutein content is salinity. This study aims to determine the best salinity to optimize the growth and production of lutein pigment in C. vulgaris. The method used is a laboratory experiment using a completely randomized design. Microalgae C. vulgaris was cultivated with three different levels of salinity treatment, namely 20, 25, 35 and 30 ppt (control) with three replications. The growth of C. vulgaris was observed for 8 x 24 hours and then harvested for the calculation of its biomass. The wet biomass from the cultivation was extracted using acetone PA as a solvent. The acetone extract of C. vulgaris was then analyzed for its lutein pigment content by spectrophotometry. The highest content of lutein pigment C. vulgaris was produced at a salinity of 35 ppt, namely 0.011363 g/g. Based on the results of the study, it can be concluded that the salinity treatment had a significant effect on the lutein pigment content of C. vulgaris.
Makroalga Yang Berasosiasi dengan Ekosistem Lamun di Perairan Teluk Awur dan Bandengan, Jepara, Jawa Tengah
Authors: Sianipar Dimpos Jonathan , Yulianto Bambang , Riniatsih Ita
Published: May 2022

Makroalga merupakan salah satu organisme laut yang memiliki peranan penting dalam mempertahankan keseimbangan ekosistem laut dangkal dan merupakan tumbuhan yang dapat hidup beraosiasi dengan ekosistem lamun. Tujuan pengamatan dilakukan untuk mengetahui jenis makroalgae, kandungan nitrat dan fosfat pada air serta hubungannya terhadap tutupan makroalga di padang lamun Teluk Awur dan Pantai Bandengan, Jepara. Data persentase tutupan makroalaga dan lamun diambil menggunakan metode transek kuadran (0,5 x 0,5 m). Analisis kandungan nitrat menggunakan metode yaitu SNI 06-6989.31-2005 dan fosfat IK-BP2-MU-A-08. Hasil penelitian menunjukkan tutupan makroalagae di Pantai Bandengan yaitu 8,47% tergolong pada kategori sedikit, dibandingkan dengan Teluk Awur yaitu 42,87% tergolong kategori melimpah. Kandungan nitrat dan fosfat rata-rata pada air di Teluk Awur adalah 3,26 ppm dan 0,39 ppm, sedangkan kandungan nitrat dan fosfat pada air di Pantai Bandengan adalah 3,69 ppm dan 0,37 ppm. Analisis regresi korelasi menunjukan kandungan nitrat dan fosfat pada air terhadap persentase tutupan makroalga di Teluk Awur menunjukan kuat positif sedangkan fosfat tidak linear, sedangkan di Pantai Bandengan memiliki hubungan positif sedang untuk nitrat dan positif rendah untuk fosfat.Macroalgae are plants that can live in association with seagrass ecosystems.. This research was conducted on 8-9 November 2020 which aims to determine the types of macroalgae, nitrate and phosphate content in water and their relationship to macroalgae cover in the seagrass beds of Teluk Awur and Bandengan Beach, Jepara. Data on the percentage of macroalage cover in seagrass beds refers to the line transeck quadratic method from LIPI. The method used to analyze the nitrate content is SNI 06-6989.31-2005 and phosphate IK-BP2-MU-A-08. Data analysis using Pearson-correlation analysis method. The results showed that the macroalgae cover in Prawean Beach was 8.47% classified in the low category, compared to Teluk Awur, which was 42.87% classified in the abundant category. The average nitrate and phosphate content in the water in Teluk Awur is 3.26 and 0.39 ppm, while the nitrate and phosphate content in the water at Bandengan Beach is 3.69 and 0.37 ppm. Regression analysis showed that the nitrate and phosphate content in the water to the percentage of macroalgae cover in Teluk Awur showed a strong positive while phosphate was moderately negative, while in Bandengan Beach there was a moderate positive relationship for nitrate and low positive for phosphate.
Kandungan Logam Berat di Tambak Gracilaria verrucosa Desa Lontar Kabupaten Serang
Authors: Sasongko Agung Setyo , Rudi Mad , Surya Andrian Tri Jaka , Aziz Raden Moch Thoriq , Pambudi Rikza Agung
Published: May 2022

Desa Lontar terletak di Kecamatan Tirtayasa, Banten. Perairan Pesisir Desa Lontar hidup berbagai biota seperti ikan, kerang dan biota lainnya. Perairan desa Lontar juga memiliki tambak budidaya rumput laut yang cukup luas. Tambak budidaya rumput laut tersebut berada cukup dekat dengan pemukiman masyarakat sekitar. Seiring pesatnya pembangunan yang terjadi di desa lontar memberikan dampak positif dan dampak negatif bagi makhluk hidup dan lingkungan di sekitar. Penelitian ini bertujuan untuk menganalisa kondisi kandungan logam berat di tambak rumput laut Desa Lontar. Metode yang digunakan adalah dengan mengambil sampel dilaksanakan di tiga titik stasiun menggunakan botol sampel, dengan pengambilan sampel sebanyak satu botol di setiap stasiunnya dan  analisis logam berat di Dinas Lingkungan Hidup dan Kehutanan Unit Pelaksanaan Teknis Labolatorium Lingkungan hidup sesuai aturan baku mutu yang ditetapkan dalam Peraturan Pemerintah Republik Indonesia Nomor 22 Tahun 2021 Tentang Penyelenggaraan Perlindungan dan Pengelolaan Lingkungan Hidup. Hasilnya menunjukan bahwa Perairan  di  Tambak Rumput Laut Desa Lontar mengandung beberapa logam berat di atas ambang batas baku mutu untuk besi (Fe), Mangan (Mn), dan Tembaga (Cu). Rumput laut Gracilaria verrucosa mampu menyerap kandungan logam berat dalam skala rendah. Kandungan logam berat tinggi dalam wilayah tambak akan berdampak kepada pertumbuhan rumput laut tersebut.   Lontar Village is located in Tirtayasa District, Banten. The coastal waters of Lontar Village live various biota such as fish, shellfish and other biota. The waters of the lontar village also have a fairly extensive seaweed cultivation pond. The seaweed cultivation pond is located quite close to the surrounding community settlements. Along with the rapid development that occurred in the village of lontar, it has a positive and negative impact on living things and the environment around them. This study aims to analyze the condition of heavy metal content in seaweed ponds in Lontar Village. The method used is to take samples carried out at three stations using sample bottles, with one bottle sampling at each station and heavy metal analysis carried out in the at the Environment and Forestry Service Environmental Laboratory Technical Implementation Unit according to standard rules. quality as stipulated in Government Regulation of the Republic of Indonesia Number 22 of 2021 concerning the Implementation of Environmental Protection and Management. The results show that the waters in the Lontar Village Seaweed Pond contain several heavy metals above the quality standard thresholds for iron (Fe), Manganese (Mn), and Copper (Cu). Seaweed can absorb heavy metal content but on a low scale, if it absorbs too much heavy metal it will have an impact on the growth of the seaweed.
Perinatal presepsin assessment: a new sepsis diagnostic tool?
Authors: Botondi Valentina , D’Adamo Ebe , Plebani Mario , Trubiani Oriana , Perrotta Marika , Di Ricco Laura , Spagnuolo Cynzia , De Sanctis Sara , Barbante Elisabetta , Strozzi Maria Chiara , Maconi Antonio , Gazzolo Francesca , Betti Marta , Roveta Annalisa , Levantini Gabriella , Gazzolo Diego
Published: May 2022

Perinatal sepsis constitutes a medical emergency and is still one of the major causes of mortality and morbidity. The possibility of an early diagnosis of sepsis is still debated and controversial. In particular, clinical symptoms can be hidden by the association of sepsis with other perinatal diseases and/or by therapeutic strategies performed. In this context, there is evidence that the accuracy of standard of care diagnostic parameters (i.e. blood culture, C-reactive protein, procalcitonin) can be biased by additional confounding factors (gestational age, birth-weight, acute-chronic hypoxia). Therefore, the inclusion in clinical daily practice of new biomarkers of sepsis is of utmost importance. Of a panel of biomarkers, Presepsin (P-SEP) plays an important role in the development and response of the immune system and as an early marker of sepsis both in adult and pediatric patients. Therefore, in the present review we aim to offer an overview of the role of P-SEP in the early detection of perinatal sepsis as a trustworthy marker according to actual statements of official international institutions. Future perspectives regard the possibility of a longitudinal non-invasive biological fluids P-SEP assessment thus limiting the sample stress in high risk newborns.
The crystal structure of 4,4′-bipyridinium bis-(2-hydroxy-3-methoxybenzoate), 2(C8H7.68O4)·C10H8.64N2
Authors: Angevine Devin J. , Benedict Jason B.
Published: May 2022

C26H24N2O8, monoclinic, P21/c (no. 14), a = 6.9170(9) Å, b = 26.012(3) Å, c = 12.7449(17) Å, β = 91.896(4)°, V = 2291.9(5) Å3, Z = 4, R
gt(F) = 0.0471, wR
ref(F
2) = 0.1320, T = 90 K.
Etching of Manganese Aluminum Bronze by Ultrasound in Seawater
Authors: Biezma M. V. , Gómez de la Rasilla O. , Haubner R. , Linhardt P.
Published: May 2022

Manganese Aluminum Bronze (MAB), UNS designation C95700, is an alloy widely used for large marine propellers and other components in hydropower units. MAB has a complex microstructure due to precipitation of intermetallic phases as consequence of the cast process or thermal treatments. When investigating the marine corrosion behavior of MAB alloys, it was found that a metallographic etching attack occurred under the effect of ultrasound, similar to that observed with chemical reagents used for high-alloy bronzes. The main aim of this work is to compare the effects of etching on polished metallographic samples by ultrasound in seawater with that obtained with conventional chemical agents. It can be concluded that the effect of ultrasound is able to reveal, with great precision, the microstructure of MAB alloys, without the use of aggressive chemical agents, while the time under the influence of ultrasonic energy allows for fine-tuning the etching effect.
Radical institutional changes while maintaining strong links between VET and the labour market: The Dutch VET experience
Authors: Broek Simon
Published: May 2022

This article intends to show that while the strong VET-labour market link has a long tradition in the Netherlands and likely maintains strong in the future, the dynamics that substantiate this link, especially in terms of institutional arrangement have seen a radical shift in the last decades. To explore the shifts we make use of Rageth and Renold (2020) model of three ideal types of linkages between education and employment system and the ideas concerning vocational and academic drift (Hippach-Schneider, 2014; Cedefop, 2017, 2020). This article is based on a literature review and case studies conducted in recent years on the Dutch system in the context of various (European) research projects. The article concludes that while the ownership for VET of the employment system decreased, the VET schools, due to the high level of autonomy and institutional capacities, were effectively able to install cooperation mechanism, joint delivery mechanisms in VET programmes and effective feedback mechanisms. The article shows that powerbalancing on VET content and supporting vocational drift does not necessarily require powerbalancing institutionally. In doing so, the article offers reflections to other countries’ VET systems on how to balance education and labour market systems in the determination of the VET content and the governance of the VET system.
Ultrasound-assisted enzymatic extraction of soluble dietary fiber from fresh corn bract and its physio-chemical and structural properties
Authors: Geng Ningning , Song Jiangfeng , Luo Shuwei , Li Ying , Wu Gang , Liu Chunquan , Wu Caie
Published: May 2022

The soluble dietary fiber from fresh corn bract (FCB-SDF) was extracted by ultrasonic-assisted cellulase method. The process parameters of FCB-SDF were optimized by Box–Behnken design (BBD), and the physio-chemical properties and structure of FCB-SDF obtained were investigated. The results showed that the optimal extraction conditions for FCB-SDF were enzyme concentration 1.58%, ultrasonic power 300 W, and extraction time 90 min. Under the above conditions, the FCB-SDF yield reached 21.21%. Compared with ultrasonic treatment group (U-SDF) and enzymatic treatment group (E-SDF), ultrasound-assisted enzymatic treatment group (UE-SDF) had higher WHC and OHC, but lower WSC. Its particle size was smaller, and a more microscopic pore structure was formed. UE-SDF had a low molecular weight of 204.41 KDa, and its monosaccharide composition had the highest arabinose content, followed by glucose. The SDFs obtained might be mainly composed of pectin and hemicellulose, E-SDF and UE-SDF contained more hemicellulose, and U-SDF contained more pectin.
Forum of young cardiologists “From prevention to high-tech care for cardiovascular diseases”
Authors: Editorial Article
Published: May 2022

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