bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Strengthening Behavior of Beams using Steel Plates
Authors: Sevim Barış
Published: July 2023

This study presents the investigation of structural response of strengthened cantilever beams using steel plates. For the purpose a rectangular section is selected and full-scaled beams are three dimensionally modeled using finite element method. The dimensions of the beams such as width, height and length are selected as 25 cm, 50 cm and 300 cm, respectively. In the study, three different beam models are included to investigate the structural response of beams. First model is called as Model-1 and it considers only a traditional RC beam. Second model is called as Model-2 and it considers rectangular concrete section covered with steel plates. In model-2, thickness of the steel plate is selected as 2.5 mm. Third model is called as Model-3 and it is similar to Model-2, but the thickness of the steel plate is selected as 5 mm. Model-2 and Model-3 are used to strength the Model-1 to investigate the strengthening effects on the structural response of the traditional beam. In the study, all models and analyses are performed using ANSYS software. The rebar, concrete and steel plates are represented with LINK180, SOLID65, and SOLID185 elements, respectively. Boundary conditions are defined on started section as fixed and ended section as free. Interface between concrete and steel plates is assumed as bounded. Nonlinear pushover analyses of beam models are performed and displacements and stresses obtained from analyses are presented as graphics through beam length and contour diagrams. The results showed that strengthened beams (Model-2 and Model-3) have more capacity compared to traditional beam (Model-1).
Psychological Contracting Process Model: Towards A Unifying Theory Of Psychological Contract
Authors: Njenga Francis Ndirangu
Published: July 2023

Although the concept of psychological contract was introduced in organization behavior more than fifty years ago, the proliferation of writings on the subject has yielded many definitions and measurements which threaten its explanatory power in social sciences. Indeed authors have evaded attempts on theory building including the phenomenology of the contracting process which would render validity to the construct. This article explains a model for the psychological contract process which aids us develop an epistemic definition as well as how the construct related to other concepts in the horizon. The approach involved knowledge blending of the disciplines of psycho-linguistics, law and social psychology. In psycholinguistic there are three conceptual fields such as perceptions, mind and thoughts. The mind sub-stream has language (communicative actions) as one of the components with language processing as sub component that yields the speech production for example performative acts. Speech acts have an overarching objective to persuade someone, make good impression or build trust and loyalty exchanges. The psychological contract process model articulated in this article comprise of contract cognitive effort/input phase, cognitive priming/instrumentation phase and cognitive state at priori domain of the contract. The input phase is an activity involving communicative action of undertaking to satisfy interest, desires, needs or goals of a referent other; followed by achievement of activation of expectations and then accomplishment level of satisfaction of the promise. Finally the posteriori domains comprise of the trust affection and loyalty behaviors as a consequent of the cognitive state. This process model will enable us distinguish between the notion of a contract as established in law, economics and sociology and that of psychological contract. Moreover it allows us move the current debate forward and towards a unifying theory of psychological contract.
Digital transformation of healthcare through the prism of trends, challenges and principles
Authors: Turkanović Muhamed
Published: July 2023

Based on the theoretical research method perspective, we present the complex topic of digitalizing the healthcare domain. We start withthe elaboration of the keywords connected to digitalization and continue with a slight overview of principles, trends, and challenges. Thepaper is limited only to the digital transformation processes and thus excludes insights into technology-related topics like nanomedicine,bioengineering, etc. While presenting the trends, we try to emphasize the key novel technologies currently being used to supporthealthcare digitalization endeavors. We conclude by highlighting the most important actions and initiatives (focusing on the EU market),which are and will be of high importance for the healthcare domain in the future.
The Performance of EU CEE Universities Against the UN Sustainable Development Goals
Authors: Szemlér Tamás
Published: July 2023

The Sustainable Development Goals (SDGs) of the United Nations (UN) play an important role in raising societies’ consciousness regarding the sustainability of our planet – a key issue for everyone. The purpose of this paper is to present and assess the performance of universities in EU CEE-11 countries (the 11 Central and Eastern European Member States of the European Union) against the UN SDGs. For this, we analyse the results of EU CEE-11 universities in the Times Higher Education Impact Rankings that are available in four editions (for the period 2019-2022). The results of the analysis reflect the still quite modest level of SDG awareness in higher education in the region, but also the progress in this respect (the increasing number of universities participating in the ranking), as well as the differences between the individual countries. Based on these findings, we identify and describe specific proposals for raising SDG awareness and strengthening SDG-related actions in EU CEE universities, contributing also to the strengthening of their reputation in the international higher education community.
Sustainable Human Resource Management
Authors: Gričnik Ana Marija , Mulej Matjaž , Šarotar Žižek Simona
Published: July 2023

Sustainable HRM (SHRM) is a new approach to people management, focusing on long-term HRM, regeneration, and renewal. It helps firms attract and retain high-quality employees: by integrating SHRM practices into their employee value proposition, firms establish unique, attractive employer brands. Socially Responsible HRM, Green HRM, Triple Bottom Line HRM, and Common Good HRM are types of SHRM. Especially these characteristics of SHRM matter: Long-term orientation, care for employees, environment, profitability, employee participation and social dialogue, employee development, external partnership, flexibility, compliance beyond labor regulations, employee cooperation, fairness, equality. SHRM is based on sustainable HR policies, such as management of employment relationships, prevention, health and safety at work, training and continuous development, diversity and equal opportunities, fair remuneration and social benefits, communication, transparency, social dialogue, attraction, and retention of employees, work–family balance. The paper presents a possible requisitely holistic model of SHRM.
Blockchain Technology in Banking as a Tool Towards the SDGs
Authors: Amon Aleksandra , Jagrič Timotej
Published: July 2023

Purpose of this paper is to investigate potential implications of blockchain in banking and its contribution towards the Sustainable Development Goals (SDGs). We use qualitative analysis based on case study analysis and netnography for determining existing and potential implications of blockchain in banking and their possible contributions towards the SDGs. This paper’s originality is finding specific potential contributions of blockchain technology in banking towards SDGs, such as towards ending poverty with increasing financial inclusion, promoting well-being for all with improving banking institutions’ performance and towards climate action by reducing banking institutions’ environmental print with digitalizing their processes and services.
Defining the Impact of Non-financial Reporting on the Process, Instrumental and Institutional Dimensions of Corporate Governance
Authors: Čufar Matic , Primec Andreja , Belak Jernej
Published: July 2023

With the adoption of the Non-Financial Reporting Directive (NFRD) and the Corporate Sustainability Reporting Directive (CSRD), selected companies have to include and publish non-financial information in the course of their annual business reports (such as environmental and social matters etc.). This paper aims to determine the methodology and develop a research model to evaluate the impact of non-financial reporting requirements on the selected companies' process, as well as instrumental and institutional dimensions of corporate governance. Research methodology and research model will be defined in application with the MER model of integral management and governance (MER model). In connection with the MER model, this paper aims to contribute to the theoretical body of literature by developing a new research model using NFRD, CSRD, and EFRAG requirements to measure how nonfinancial reporting impacts process, instrumental and institutional dimensions of corporate governance. This paper also sought to illustrate the value and expected results of the future study when the research model is used in an empirical survey. A company must meet non-financial reporting requirements through all three dimensions of governance (process, instrumental, and institutional) to contribute to the company's long-term success, the well-being of society, and the achievement of sustainable development goals.
Harmony and Normalisation in Bilateral Logic
Authors: Del Valle-Inclan Pedro
Published: July 2023

In a recent paper del Valle-Inclan and Schlöder argue that bilateral calculi call for their own notion of proof-theoretic harmony, distinct from the usual (or ‘unilateral’) ones. They then put forward a specifically bilateral criterion of harmony, and present a harmonious bilateral calculus for classical logic.
In this paper, I show how del Valle-Inclan and Schlöder’s criterion of harmony suggests a notion of normal form for bilateral systems, and prove normalisation for two (harmonious) bilateral calculi for classical logic, HB1 and HB2. The resulting normal derivations have the usual desirable features, like the separation and subformula properties. HB1-normal form turns out to be strictly stronger that the notion of normal form proposed by Nils Kürbis, and HB2-normal form is neither stronger nor weaker than a similar proposal by Marcello D’Agostino, Dov Gabbay, and Sanjay Modgyl.
Virome of Mosquitoes from Natural Landscapes of the Western Siberia
Authors: Ternovoi Vladimir A. , Shvalov Alexander N. , Kartashov Mikhail Yu. , Ponomareva Eugenia P. , Tupota Natalia L. , Khoroshavin Yuri A. , Bayandin Roman B. , Gladysheva Anastasia V. , Mikryukova Tamara P. , Tregubchak Tatyana V. , Loktev Valery B.
Published: July 2023

Metagenomic analysis of mosquitoes allows the genetic characterization of mosquito-associated viruses in different regions of the world. This study applied the metagenomic approach to search for novel viral sequences in seven species of mosquitoes collected from the Novosibirsk region of Western Siberia. Using NGS sequencing, we identified 15 coding-complete viral polyproteins (genomes) and 15 viral-like partial sequences in mosquitoes. The complete sequences for novel viruses or partial sequences of capsid proteins, hypothetical viral proteins, and RdRp were used to identify their taxonomy. The novel viral sequences were classified within the orders Tymovirales and Picornavirales, the families Partitiviridae, Totiviridae, Tombusviridae, Iflaviridae, Nodaviridae, Permutotetraviridae, Solemoviridae, with several attributed to four unclassified RNA-viruses. The main part of the novel putative viruses and viral sequences was associated with Coquillettidia richardii mosquito. This study is intended to increase our understanding of viral diversity in mosquitoes found in the natural habitats of Siberia, characterized by very long, snowy, and cold winters.
Numerical Investigation on a Solar Heating System with Solar Tower Receiver and Seasonal Storage in North China: Dynamic Performance Assessment and Operation Strategies Analysis
Authors: Li Xiaoxia , Qiu Husheng , Wang Zhifeng , Li Jinping , Yuan Guobin , Guo Xiao , Chen Longfei
Published: July 2023

Solar heating technology is a promising solution to promote China to achieve the “3060 double carbon” target as soon as possible. And seasonal thermal storage (STS) can effectively solve the mismatch problem of solar heating systems between the supply and demand of thermal energy. Due to the instability of solar radiation resources and heat demand, it is necessary to analyze the dynamic response characteristics of the system. Yet, related studies are still scarce. In this study, a solar heating system with a solar tower receiver and STS was introduced in north China. The dynamic performance of the system is analyzed with a dynamic simulated method in a typical day or typical operation modes, and the switch mechanism between multiple operation modes is also revealed. The impact of different heating strategies on system performance was analyzed. Results showed that the solar fraction of the system reached 89.4% in the third year, which was 3.6% higher than the first year. The quality-quantity heating operation strategies can be effective ways to improve the discharge efficiency of STS and the system performance without any heat pump. The electricity consumption of the pump on the heating side could be significantly reduced by 44.6% compared with the quality control.
Intelligent Syringe for Porous Tissue Characterization Using Advanced Darcy Flow Pressure Transient Analysis
Authors: Chin Wilson C. , Chin Jamie A. , Zhuang Xiaoying
Published: July 2023

An instrumented “intelligent syringe” for tissue properties prediction is described. The syringe records pressure transients created while injecting or withdrawing fluid from tissue at given flow rates. Dynamic data is interpreted using computer-based porous media math models to predict permeability, anisotropy, compressibility, background pressure and porosity. The new method provides direct measurements of flow properties important to drug delivery, clinical diagnosis, disease control, synthetic organ design and research endeavors. The approach conveniently, rapidly and inexpensively supplements conventional methods like X-ray, Catscan, MRI and ultrasound, which offer qualitative results through gray scale images requiring physician dependent and subjective analysis. The “iSyringe” supports portable target monitoring on daily or weekly bases; it provides local quantitative information useful in understanding global qualitative results obtained from traditional methods. The theoretical foundations of the method are derived, validated mathematically, and applied to published human and animal data, highlighting potential clinical and research applications.
Decreasing the environmental impact of carbon fibre production via microwave carbonisation enabled by self-assembled nanostructured coatings
Authors: Stróżyk Michał A. , Muddasar Muhammad , Conroy Timothy J. , Hermansson Frida , Janssen Matty , Svanström Magdalena , Frank Erik , Culebras Mario , Collins Maurice N.
Published: July 2023

The use of carbon fibre (CF) based composites is of growing global importance due to their applications in high end sectors such aerospace, automotive, construction, sports and leisure amongst others. It is forecast that composites will reach a global market value of $131.6 bn by 2024. However, their current high production cost, high carbon footprint and reduced production capability, limits their use to high performance and luxury applications. Approximately 50 % of the total cost of CF production is due to the thermal conversion of PAN precursor fibre (PF) to CF as it involves the use of high energy consumption and low heating efficiency large furnaces. Looking at this scenario we propose in the present study to use microwave (MW) heating to convert PF to CF. This is scientifically and technologically challenging since PF does not absorb microwave energy. Here, for the first time we show how carbonisation temperatures of >1000 ºC can be reached in a matter of seconds through the use of a novel microwave (MW) susceptor nanocoating methodology developed via a Layer-by-layer assembly of multiwall carbon nanotubes (MWCNTs) on the PF surface. Remarkably, these CFs can be produced in an inexpensive domestic microwave and exhibit mechanical performance equivalent to CF produced using conventional heating. Additionally, we provide a life cycle and environmental impact analysis which shows that MW heating reduces the energy demand and environmental impact of lignin-based CF production by up to 66.8% and 69.5%, respectively.
Pure large cell neuroendocrine carcinoma of the ovary with a somatic BRCA1 mutation: the first reported case and the review of the literature
Authors: Wang Musen , Gao Fei , Wang Xiao , Guo Yebing , Zhang Hongkai
Published: July 2023

Pure large cell neuroendocrine carcinomas (pLCNEC) of the ovary are extremely rare, so there is a lack of molecular information on this type of cancer. Herein, we presented a pure primary LCNEC of the ovary with a pathogenic somatic mutation at the c.5332 + 1g > a splice site of the BRCA1 gene. To the best of our knowledge, this is the first report of a BRCA1 somatic mutation found in the ovary LCNEC. Testing BRCA1/2 mutations in patients with ovarian LCNEC might be worth considering, as these patients may benefit from the targeted treatment. We present a unique case that expands our understanding of this rare entity.
A novel diagnostic model for Tuberculous meningitis using Bayesian Latent class analysis
Authors: Dong Trinh Huu Khanh , Donovan Joseph , Nghiem Ngoc My , Do Thu Dang Anh , Ho Nghia Dang Trung , Pham Oanh Kieu Nguyet , Nguyen Phu Hoan , Vu Hang Thi Ty , Nguyen Vinh-Chau Van , Nguyen Thuong Thuong Thuy , Le Tan Van , Thwaites Guy Edward , Geskus Ronald Bestus
Published: July 2023

Background

Diagnosis of tuberculous meningitis (TBM) is hampered by the lack of a gold standard. Current microbiological tests lack sensitivity and clinical diagnostic approaches are subjective. We therefore built a diagnostic model that can be used before microbiological test results are known.

Methods

We included 659 individuals aged at least 16 years with suspected brain infection from a prospective observational study conducted in Vietnam. We fitted a logistic regression diagnostic model for TBM status, with unknown values estimated via a latent class model on three mycobacterial tests: Ziehl-Neelsen smear, Mycobacterial culture, and GeneXpert. We additionally re-evaluated mycobacterial test performance, estimated individual mycobacillary burden, and quantified the reduction in TBM risk after confirmatory tests were negative. We also fitted a simplified model and developed a scoring table for early screening. All models were compared and validated internally.

Results

Participants with HIV, miliary TB, long symptom duration, and high cerebrospinal fluid (CSF) lymphocyte count were more likely to have TBM. HIV and higher CSF protein were associated with higher mycobacillary burden. In the simplified model, HIV infection, clinical symptoms with long duration, and clinical or radiological evidence of extra-neural TB were associated with TBM At the cutpoints based on Youden’s Index, the sensitivity and specificity in diagnosing TBM for our full and simplified models were 86.0% and 79.0%, and 88.0% and 75.0% respectively.

Conclusion

Our diagnostic model shows reliable performance and can be developed as a decision assistant for clinicians to detect patients at high risk of TBM.
A Unified Kinetic Picture of Heterogeneous and Homogeneous Crystallization from Transition Rate
Authors: Xu Lei , Chen Zhen
Published: July 2023

Heterogeneous and homogeneous crystallization exhibit distinct phase transition kinetics. However, due to the difficulty of realizing both heterogeneous and homogeneous crystallization under one identical thermodynamic condition, an independent comparison of the two remains lacking. Inside a colloidal system, we experimentally realize a systematic switching from heterogeneous to homogeneous crystallization under one identical thermodynamic condition, capture the entire crystallization process of each colloidal particle with confocal microscopy, and discover a universal kinetic picture of the two situations. In the heterogeneous crystallization, we reveal an unexpected variation of critical nucleus size with boundary disorderness instead of contact angle, which violates the classical nucleation theory but enables the systematic switching. Moreover, analogous to the reaction rate in chemical reactions, we theoretically propose and experimentally measure the crystallization transition rate, which quantifies the transition probability between any two crystallization intermediate structures identified by the bond order parameters. To our surprise, regardless of heterogeneous or homogeneous crystallization, all 22 kinetic transition rates fall onto universal master curves throughout both nucleation and growth stages, which unifies the two distinct crystallization situations into a universal kinetic picture, i.e., all transition probabilities only depend on the local order parameter but not the heterogeneous or homogeneous mode.
BCL9 is a risk factor of neck lymph nodes metastasis and correlated with immune cell infiltration in papillary thyroid carcinoma
Authors: Zhang Rui , Gui Zhengwei , Zhao Jianguo , Zhu Di , Zhao Lu
Published: July 2023

Purpose
BCL9 contributed to tumor progression and metastasis in various tumors, whereas, the role of BCL9 in papillary thyroid cancer (PTC) hasn’t been investigated.
Methods
We acquired PTC gene expression data from The Cancer Genome Atlas (TCGA) databases. 59 PTC tissues were applied to validate the clinical significance of BCL9. Cell experiments were applied to investigate the role of BCL9. Bioinformatics analysis were employed to investigate the biological functions of BCL9.
Results
We found that BCL9 was higher expressed (P ༜ 0.05) and an independent risk factor for lymph node metastasis (OR = 3.770, P = 0.025), as well as associated with poorer progression free survival (PFS) (P = 0.049) in PTC. BCL9 knockdown inhibited proliferation and invasion of PTC cells. BCL9 was positively associated with the key genes of Wnt/β-catenin and MAPK pathway by Co-expression analysis. GO, KEGG and GSEA analysis showed BCL9 might participated in PPAR, cAMP, and focal adhesion pathway. CIBERSORT analysis found BCL9 was negatively associated with CD8 + T cells and NK cells infiltration and positively with PD-L1 expression.
Conclusion
Therefore, BCL9 was associated with lymph node metastasis and shorter PFS of PTC, due to promotion of PTC cell proliferation and invasion, activation of Wnt/β-catenin and MAPK pathway, inhibition of CD8 + T and NK cells infiltration, and promotion of PD-L1 expression.
Air Pollution, Health Expenditures and Multilevel Medical Insurance Systems: Evidence from China
Authors: Wang Ennan , Zhu Minglai , Lin Yisha , Xi Xiaoyu
Published: July 2023

Background
Air pollution affects residents' health to varying extents according to differences in socioeconomic status. However, there has been a lack of research on whether air pollution contributes to unfair health costs.
Methods
In this research, data from the Labour Force Dynamics Survey are matched with data on PM2.5 average concentration and precipitation, and the influence of air pollution on the health expenditures of residents is analysed with econometric methods involving a two-part model, instrument variables and moderating effects.
Results
The findings reveal that air pollution significantly impacts residents’ health costs and leads to low-income people face health inequality. Specifcally, the empirical evidence shows that air pollution has no significant influence on the probability of residents’ health costs (β =0.021, p=0.770) but that it increases the amount of residents’ total outpatient costs (β =0.379, p<0.006), reimbursed outpatient cost (β =0.453, p<0.044)and out-of-pocket outpatient cost (β =0.362, p<0.048). The heterogeneity analysis of income indicates that low-income people face inequality due to health cost inflation caused by air pollution, their total and out-of-pocket outpatient cost significantly increase with PM2.5 (β =0.417, p=0.013; β =0.491, p=0.020). Further analysis reveals that social basic medical insurance does not have a remarkable positive moderating effect on the influence of air pollution on individual health inflation (β =0.021, p=0.292), but supplementary medical insurance for employees could reduce the effect of air pollution on low-income residents’ reimbursed and out-of-pocket outpatient cost (β =-1.331, p=0.096; β=-2.211, p=0.014).
Conclusion
The study concludes that air pollution increases the amount of residents’ outpatient cost and has no significant effect on the incidence of outpatient cost. However, air pollution has more significant impact on the low-income residents than the high-income, which indicates that air pollution leads to the inequity of medical cost. Additionally, the supplementary medical insurance reduces the inequity of medical cost caused by air pollution for the low-income employees.
Long-term survival analysis of microwave ablation for hepatocellular carcinoma comforming to the Milan crititia: primary versus recurrent HCC
Authors: Zhang Jing , Guo Guanya , Li Tao , Guo Changcun , Han Ying , Zhou Xinmin
Published: July 2023

Background
Whether microwave ablation (MWA) is as effective in initial hepatocellular carcinoma (IHCC) as in recurrent HCC (RHCC) is unclear.We aim to compare the long-term outcomes for IHCC and RHCC conforming to the Milan criteria.
Methods
In this retrospective study, 425 Milan-eligible patients (294 IHCCs, 131 RHCCs) who underwent MWA from January 2008 to November 2021 were included. All the patients with RHCC had MWA as initial treatment. Propensity-score matching (PSM) analysis was used to assess the overall survival (OS) and recurrence-free survival (RFS) between IHCC and RHCC.
Results
After PSM, OS in IHCC was better than in RHCC, with OS rates at 1, 3, 5, and 10 years in IHCC were 97.5%, 79.7%, 54.6% and 38.4%, respectively, and in RHCCs were 94.1%, 69.2%, 42.4% and 5.6%, respectively. However, subgroup analyses suggested that there were no significantly differences in OS between IHCC and RHCC in patients with solitary HCC ≤ 3.0 cm, AFP ≤ 200 ng/mL, or ALBI grade 1. Patients with RHCC had worse RFS than those with IHCC in the entire and PSM cohorts, as well as in the subgroup analyses. No association between time to recurrence with OS and RFS was identified in patients who received repeat MWA.
Conclusions
Although RHCC patients had worse prognosis than IHCC patients, MWA could be used as an effective treatment for RHCC as in patients with single small tumor, lower AFP level, and good liver function reserve regardless of time to recurrence. Close surveillance should be taken in RHCC patients after MWA.
Bovine trichomoniasis overview and testing
Authors: Funnel Bethany J.
Published: July 2023

Bovine trichomoniasis, caused by Tritrichomonas foetus, is a venereal disease of cattle, resulting in infertility, pregnancy losses, abortion and delayed calving seasons. The disease has global distribution, with greater prevalence in areas in which natural service is the primary means of reproduction. When ar­tificial insemination, with appropriate hygiene practices, is im­plemented, as well as aggressive testing and culling of positive bulls, control and eradication of the disease is possible. Addi­tionally, minimizing co-mingling of animals with unknown sta­tus through herd additions or on public grazing lands will help decrease the likelihood of introduction into negative herds, and contribute significantly to the decrease in prevalence in the local region. Testing methods have improved over the last 100 years; however, proper sample collection and handling are still paramount to gaining true positive results in infected bulls.
Environmental impact of feed additives in cattle production
Authors: Kebreab Ermias
Published: July 2023

Cattle production is one of the main contributors to methane emissions globally. Although there are nutritional, genetic and other methods to reduce methane emissions from cattle operations, feed additives have the potential to substantially decrease emissions. These can be broadly categorized based on their mode of action into 2 main groups. Feed additives can either directly inhibit methanogens that are responsible for methanogenesis or modify the rumen environment to reduce the amount of methane produced. In general, inhibitors such as 3-nitrooxypropanol and macroalgae reduce emissions by 30 to 80%. Feed additives that work indirectly generally reduce emis­sions by less than 25%. However, a combination of the 2 types may increase the level of anti-methanogenic effectiveness. Some of the most effective feed additives are expected to be available commercially in 2022-2023 in some parts of the world contributing to methane mitigation efforts.
Emerging technologies in dairy medicine
Authors: Caixeta Luciano S. , Shepley Elise
Published: July 2023

Technology is often adopted in dairy farming for one – or many – of the following reasons: to increase farm efficiency, improve farm profitability, assist in decision-making, improve ani­mal welfare and, in some cases, increase producer happiness. As the use of technologies increases in dairy farming, dairy practitioners, who are regarded as the most reliable source of information by producers, must learn about the innovations available in the market in order to assist dairy producers when adopting these emerging technologies. More importantly, dairy producers and practitioners should leverage the large amount of data generated by these innovations to develop management actions to improve animal health, performance and welfare. This review focuses on presenting some of the emerging tech­nologies used for the management and monitoring of lactating dairy cows, and how these technologies can be used by dairy practitioners to add value to the services they offer while in­creasing farm efficiency and animal welfare.
The use of a dual-challenge Bovine Viral Diarrhea Virus-Mannheimia haemolytica model to compare vaccine efficacy in calves in the face of maternal immunity
Authors: Perkins-Oines S. , Krafsur G. , Adelsalam K. , Ensley D. , Jones C. , Chase C.
Published: July 2023

Bovine respiratory disease continues to be the greatest threat to calf health. One of the common recommendations is to vac­cinate young beef and dairy calves at 30-60 days of age to pro­vide protection at weaning or when commingled. A study was designed to determine if vaccination in the face of maternal an­tibody would provide protection against a dual challenge with bovine viral diarrhea virus (BVDV) and Mannheimia haemolyti­ca ~5 months after vaccination.
Better than the human eye – machine learning models to objectively analyze bovine embryo quality
Authors: Wells C. E. , Killingsworth R.
Published: July 2023

Machine learning (ML) is a type of artificial intelligence that al­lows software applications to become more accurate at predict­ing outcomes without being explicitly programmed. ML models use millions of parameters to detect patterns and generate al­gorithms which can provide image analysis and predictive out­put superior to the human eye. ML models offer value to many biological applications, including the evaluation and selection of bovine embryos in conventional embryo transfer (ET) and in vitro fertilization (IVF). The objective of this study was to train ML models to evaluate bovine embryo viability and test their prediction accuracy against known pregnancy outcomes.
Special transition and extraordinary phase on the surface of a two-dimensional quantum Heisenberg antiferromagnet
Authors: Ding Chengxiang , Zhu Wenjing , Guo Wenan , Zhang Long
Published: July 2023

Continuous phase transitions exhibit richer critical phenomena on the surface than in the bulk, because distinct surface universality classes can be realized at the same bulk critical point by tuning the surface interactions. The exploration of surface critical behavior provides a window looking into higher-dimensional boundary conformal field theories. In this work, we study the surface critical behavior of a two-dimensional (2D) quantum critical Heisenberg model by tuning the surface coupling strength, and discover a direct special transition on the surface from the ordinary phase into an extraordinary phase. The extraordinary phase has a long-range antiferromagnetic order on the surface, in sharp contrast to the logarithmic decaying spin correlations in the 3D classical O(3) model. The special transition point has a new set of critical exponents, y_{s}=0.86(4)ys=0.86(4) and \eta_{\parallel}=-0.33(1)η∥=−0.33(1), which are distinct from the special transition of the classical O(3) model and indicate a new surface universality class of the 3D O(3) Wilson-Fisher theory.
Measurement phase transitions in the no-click limit as quantum phase transitions of a non-hermitean vacuum
Authors: Zerba Caterina , Silva Alessandro
Published: July 2023

We study dynamical phase transitions occurring in the stationary state of the dynamics of integrable many-body non-hermitian Hamiltonians, which can be either realized as a no-click limit of a stochastic Schrödinger equation or using spacetime duality of quantum circuits. In two specific models, the Transverse Field Ising Chain and the Long Range Kitaev Chain, we observe that the entanglement phase transitions occurring in the stationary state have the same nature as that occurring in the vacuum of the non-hermitian Hamiltonian: bounded entanglement entropy when the imaginary part of the quasi-particle spectrum is gapped and a logarithmic growth for gapless imaginary spectrum. This observation suggests the possibility to generalize the area-law theorem to non-Hermitian Hamiltonians.
Sobre la renovación de la cultura: Humanitas y universitas
Authors: Vargas Alberto I.
Published: July 2023

Ensayo académico
Forma y libertad. La religión como unidad cultural en Ernst Cassirer
Authors: Esparza Urzúa Gustavo Adolfo
Published: July 2023

En el presente artículo se estudia la experiencia religiosa como un momento de encuentro y unidad cultural. A partir de la filosofía de la Religión propuesta por Ernst Cassirer en El pensamiento mítico, se elabora una interpretación de dos textos: el encuentro entre San Juan Diego y la Virgen María (Tonantzin Guadalupe) y Moisés y la Zarza ardiendo (Yavhé); con ambos análisis se manifiestan dos resultados centrales: (1) que la advertencia emotiva, denominado por Cassirer como “expresión simbólica”, constituye el fundamento del encuentro y unidad entre el ser humano y la divinidad y (2) que dicha expresión simbólica implican actividades rituales mediante las cuales la comprensión del misterio es posible.
Stability analysis of riverbanks with a dual structure under water–root–soil coupling
Authors: Hao Youzhi , Jia Dongdong , Zhang Xingnong , Shang Qin , Zhu Hongsheng , Fei Xiaoxin , Yang Jun , Wu Lei , Chen Changying
Published: July 2023

The collapse mechanism of dual-structure vegetation riverbanks at different water levels is unclear. A method for calculating the critical collapse width of a dual-structure vegetation bank under different failure modes that consider the variations in river and groundwater levels and the influence of vegetation roots is proposed. Combined with the influence of flow lateral erosion and slope toe accumulation, a calculation model of riverbank stability was established. The results show that shear failure is the main failure mode when the cohesive soil layer on a dual-structure bank is thick, and the critical collapse width of the bank with root soil is higher than that of the soil bank. The critical collapse width of the bank varied with the water level during different water level periods. Compared with a soil riverbank, a rooted soil riverbank can significantly prolong the bank collapse time. The collapse width of a soil bank without vegetation roots is smaller than that of a rooted soil bank, and the cumulative collapse width is related to calculation time. The greater the thickness of rooted soil, the slower the decay rate of bank stability under water flow erosion.
Hybrid electrolysis and membranes system for apple packing houses water treatment
Authors: Carpes Vanessa Maria , Rubert Aline , Graciola Samarah , Barbosa Brião Vandré , Hemkemeier Marcelo
Published: July 2023

The apple industry uses high flows of potable quality water to transport and clean the apple, which is regularly contaminated. Thus, it is necessary to implement an efficient water treatment system during the industrial process, providing reductions in the intake and release flows. A hybrid system was developed by applying the electrolytic treatment by electrocoagulation using a batch process (Step 1) and a continuous process (Step 2), followed by a microfiltration membrane separation (MSP) process (Step 3). The optimal conditions for removal of organic matter, chemical oxygen demand, total suspended solids (TSS), turbidity, color, and fungi obtained in Step 1 were a hydraulic detention time of 40 min, stirring at 40 rpm, current density of 20 A/m2, pH of 8.00, and temperature of 10 °C. These findings led to a successful implementation in Step 2, which evolved into Step 3, where tests in the combined continuous electrolytic reactor together with MSP showed significant removal rates, notably reaching up to 54% organic matter (OM) removal, 72% chemical oxygen demand (COD) removal, 83% TSS removal, 92% haze and color removal, and 100% mildew removal. The hybrid system proved to be a promising alternative for implementation in the processing industry, minimizing environmental impacts and costs.
How can Fullerenes Help in the Treatment of Diseases? A Review Article
on Pharmaceutical Usage of Fullerenes as Carriers
Authors: Masoomzadeh Salar , Gholikhani Tooba , Aminroaia Paria , Taghvimi Arezou , Javadzadeh Yousef
Published: July 2023

Drug degradation is a process that can render pharmaceuticals inactive without causing
any visible distortion. This can disrupt the therapeutic process, and on occasion, when the process
produces toxic metabolites, it can have much more fatal consequences. Light is one of the most
significant components that might cause deterioration, and several attempts have been made to improve
and increase the practical photosensitizing of nano-scaled pharmaceuticals. Considering this,
the insolubility and aggregating qualities of fullerenes have received significant attention. Fullerene
is considered to have a unique carbon structure. In order to gain improved water solubility and
biocompatible properties, fullerenes have been combined with water-soluble, biodegradable, and
adjustable polymers. More specifically, these linkers exhibit increased tumor cell identification and
greater tumor cell suppression when linked to therapeutic ligands (tumor-targeting) or stimuliresponsive
polymers. According to scientific studies, fullerene-drug combinations can be used in
certain complex diseases, like infectious and viral types. Several studies have combined fullerenes
into nano-emulsions or liposomes for various pharmacological objectives. In the current work,
fullerene/polymer nanomaterials are discussed for potential therapeutic techniques for the treatment
of various diseases, particularly cancer and AIDS. According to the research studies, fullerene
is a suitable element with outstanding physical and chemical properties that has a wide range
of potential applications in the pharmaceutical industry, including drug delivery system design,
photodynamic cancer therapy, and antioxidant therapy.
A Profound Insight into the Structural Modification of Natural Bioactive
Compounds Containing Piperazine Moiety: A Comprehensive Review
Authors: Chopra Bhawna , Saini Neha , Dhingra Ashwani K.
Published: July 2023

Piperazine is the heterocyclic nucleus and exhibits significant biological potential such
as antipsychotic, antidepressant, antihistamine, anticancer, anti-anginal, cardioprotective, antiviral,
and anti-inflammatory activity. As a result, it had been considered a crucial structural component in
the majority of the therapeutic medications that were already on the market. Other issues that limit
its use include solubility, limited bioavailability, cost-effectiveness, and a mismatch between the
drug's pharmacokinetic and pharmacodynamic profiles. Literature describes structural modification
in the piperazine moiety to create novel derivatives or analogues to solve the issues with currently
marketed medications. Nature provides various bioactive components having piperazine nuclei in
their core structure. The present review describes the potential of the piperazine nucleus present in
natural bioactive components. So the study concludes that it is vital to concentrate on the structural
characteristics of this scaffold, which opens the way for future research and may benefit pharmaceutical
companies as well as medicinal chemists.
PENGARUH KESULITAN KEUANGAN DAN PROFITABILITAS TERHADAP KECEPATAN PUBLIKASI LAPORAN KEUANGAN TAHUNAN (STUDI EMPIRIS PADA PERUSAHAAN PERTAMBANGAN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2016-2018)
Authors: Firda A Nurul , Eka P Wirmie , Olimsar Fredy
Published: July 2023

Penelitian ini bertujuan untuk menguji pengaruh kesulitan keuangan dan profitabilitas terhadap kecepatan publikasi laporan keuangan tahunan. Variabel kesulitan keuangan diukur dengan Rasio Gearing dan variabel profitabilitas diukur dengan ROA (Return On Assets). Penelitian ini menggunakan sampel perusahaan pertambangan yang terdaftar di Bursa Efek Indonesia periode 2016-2018. Teknik pengambilan sampel dalam penelitian ini menggunakan purposive sampling. Sampel yang digunakan dalam penelitian berjumlah 38 perusahaan dengan total data penelitian 114 data. Teknik analisis data yang digunakan dalam penelitian ini adalah statistik deskriptif dan analisis regresi linier berganda dengan menggunakan software SPSS versi 23 for windows. Hasil pengujian hipotesis pada penelitian ini menunjukkan bahwa kesulitan keuangan dan profitabilitas secara simultan berpengaruh terhadap kecepatan publikasi laporan keuangan tahunan. Secara parsial kesulitan keuangan dan profitabilitas berpengaruh signifikan terhadap kecepatan publikasi laporan keuangan tahunan. Besaran pengaruh kesulitan keuangan dan profitabilitas terhadap kecepatan publikasi laporan keuangan tahunan termasuk dalam kategori keeratan sangat lemah.
Pengaruh Tingkat Inflasi, Suku Bunga BI, dan Pertumbuhan Ekonomi Terhadap Pembiyaan Murabahah pada Bank Syariah di Indonesia ( Periode Januari 2013 – Desember 2017 )
Authors: Perdana Khori , Hamzah Emilia , Lubis Paulina
Published: July 2023

Penelitian ini bertujuan untuk menganalisa pengaruh Inflasi, Suku Bunga Bank Indonesia, dan Pertumbuhan ekonomi terhadap Pembiayaan Murabahah pada bank syariah di Indonesia. Data yang digunakan adalah data Time Series periode Januari 2013– Desember 2017, yang bersumber dari Statistik Perbankan Indonesia. Untuk menganalisis, penulis menggunakan metode Regresi Linier Berganda. Hasil penelitian ini menunjukkan bahwa variabel Inflasi, Suku Bunga Bank Indonesia, dan Pertumbuhan ekonomi berpengaruh signifikan secara parsial dan simultan terhadap Pembiayaan Murabahah. Dalam penelitian ini diketahui bahwa Inflasi berpengaruh signifikan positif terhadap Pembiayaan Murabahah. Sedangkan Suku Bunga Bank Indonesia, dan pertumbuhan ekonomi berpengaruh signifikan negatif terhadap Pembiayaan Murabahah.

Kata Kunci : Pembiayaan Murabahah, Inflasi , Suku Bunga BI , Pertumbuhan Ekonomi
Mathematics teacher educators’ noticing of pedagogical content knowledge on hierarchical classification of quadrilateral
Authors: Ekawati Rooselyna , Kohar Ahmad Wachidul , Siswono Tatag Yuli Eko , Lukito Agung , Yang Kai-Lin , Nisa Khoirun
Published: July 2023

This study aims to investigate mathematics teacher educators’ (MTE) knowledge in noticing preservice teachers’ pedagogical content knowledge (PCK) on the hierarchical classification of the quadrilateral. A multiple case study was conducted to analyze the responses of ten MTEs in an online moderated-forum group discussion (M-FGD) from their written work on the MTE-PCK test completed prior to the M-FGD. The PCK test consisted of two tasks: the task that examines MTEs’ knowledge to predict pre-service teachers’ reason in representing the hierarchical classification of quadrilateral in Venn diagrams, and the task that examines MTEs’ knowledge in making a flowchart as a recommendation to mathematics teacher to analyze the validity of quadrilateral classification. Results show that the MTEs indicate two considerations of noticing pre-service teachers’ PCK on the quadrilateral classification: by definition and properties of quadrilaterals and by the visual appearance of quadrilaterals. Despite this, 20% of them were indicated to perform a lack of understanding of the hierarchical classification of quadrilaterals, as indicated by invalid flowcharts of validating the hierarchical classification of the quadrilateral.
THE EFFECT OF LIFESTYLE AND STORE ATMOSPHERE ON CONSUMER PURCHASE DECISIONS THROUGH PURCHASE INTEREST OF INDOMARET IN TERNATE
Authors: Rusdiyanto Ayu Qur'naesih , Hidayanti Ida , Damayanti Ririn
Published: July 2023

This study aims to determine the effect of lifestyle and store atmosphere on consumer purchasing decisions through purchase interest. This research was a quantitative research. The population in this study was Indomaret consumers in Ternate City with a non-probability sampling method and a purposive sampling approach. The data analysis technique in this research used path modeling analysis using smart Partial Least Square (PLS) version 3 as a statistical test tool. The results of this study indicate that lifestyle has a significant effect on purchase decisions, store atmosphere has a significant effect on purchase decisions, lifestyle has a significant effect on puerchase interest, store atmosphere has a significant effect on purchase interest.
IMPLEMENTATION OF QUALITY FUNCTION DEPLOYMENT (QFD) IN UD. PRODUCTION FURNITURE TO DESIGN SCANDINAVIAN STYLE WARDROBE PRODUCTS
Authors: Hanifah Juliyanti
Published: July 2023

The product is an important aspect for the company because it is what the company can produce for consumers. The products created by the company must meet consumers’ wants and needs. Therefore, consumer’s wants and needs are important aspects of the company that can be reviewed to improve product quality at the company. This study aims to determine the implementation of the Quality Function Deployment (QFD) method as a problem-solving solution in designing Scandinavian-style wardrobe products at UD. Furniture Production. This research was conducted using a quantitative method with a few qualitative methods to conduct a survey related to the voice of desire and consumer satisfaction. This data collection technique used interview methods and questionnaires. Meanwhile, the sampling technique used a non-probability sampling technique, namely consumers or customers from UD. Furniture Production.