bluuebunny/crossref_metadata_2025 huggingface dataset:
A Pilot Study of RNA Sequencing to Improve the Diagnostic Yield of Bronchoalveolar Lavage Specimens in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients
Authors: Rosenblum Jeremy M. , Traeger Nadav , Welter John , Huang Weihua , Wang Guiquing , Yin Changhong , Shi Qiuhu , Harrison Lauren , Mahanti Harshini , Fallon John , Cairo Mitchell S.
Published: March 2021

Background: Pulmonary complications often cause morbidity and mortality in pediatric allogeneic hematopoietic stem cell transplant (HSCT) recipients. While detection of infection and initiation of appropriate antimicrobial therapy improves survival, present techniques oftentimes do not detect infections in bronchoalveolar lavage (BAL) samples because of pretreatment with antimicrobial therapies and the need for a priori knowledge of likely viral pathogens, decreasing the yield of BAL. Objective: We evaluated whether RNA-based massively parallel sequencing (MPS) would improve detection of infections in BAL fluid in pediatric allogeneic HSCT recipients. Results: Nine patients underwent 10 BAL (1 patient underwent 2 BAL) and had sufficient BAL fluid for inclusion in this study. Clinical microbiological testing identified infections in 7 patients, and MPS identified infections in 5 patients, although some of these detected organisms were not detected by clinical testing. Results were fully concordant in 5 patients, fully discordant in 3 patients, and partially discordant in 2 patients. Bacterial, viral, and fungal infections were detected via both techniques. Conclusion: This suggests that MPS in conjunction with routine clinical testing increases the yield of detection of infectious organisms in the BAL fluid.
Pineal Region Meningioma in a Very Young Child
Authors: Gendle Chandrashekhar , Karthigeyan Madhivanan , Salunke Pravin
Published: March 2021

Introduction: Meningiomas in childhood are infrequently seen. Furthermore, they are extremely rare at a pineal location with few reported cases above 5-years of age. We present a very young child with a large pineal region meningioma which mimicked the usually occurring pathologies at this site. Case Presentation: A 2.5-year-old child presented with symptoms of raised intracranial pressure. MRI demonstrated a homogenously enhancing pineal lesion with small cystic areas. After an initial cerebrospinal fluid evaluation for germ cell tumors, the child underwent excision of the lesion by the Krause approach. The tumor showed no definitive dural attachment, had well-defined arachnoid interface, and was completely excised. The final histopathology was meningioma. Conclusion: Although unusual, we highlight the importance of considering meningiomas among the childhood pineal region lesions, given their good outcome with total resection. Also, pertinent brief literature of the pediatric pineal region meningiomas has been provided. An assessment of preoperative and intraoperative features (clear arachnoid plane) along with adjuncts such as frozen studies can help discern various entities of this region, and decide the extent of excision.
Collision Tumor Comprising Primary Malignant Lymphoma and Adenocarcinoma in the Ascending Colon
Authors: Kataoka Jun , Nitta Toshikatsu , Ota Masato , Fujii Kensuke , Ishii Masatsugu , Senpuku Sadakatasu , Ueda Yasuhiko , Tsuchimoto Yusuke , Takeshita Atsushi , Miyatake Junichi , Ishibashi Takashi
Published: March 2021

We describe the case of a 78-year-old man with collision tumor from the primary malignant lymphoma and adenocarcinoma in the ascending colon. He suffered anemia from sigmoid colon cancer, and colonoscopy revealed early-stage colorectal cancer with a diameter of 20 mm in the cecum, the biopsy specimen showed moderately differentiated adenocarcinoma. Contrast-enhanced computed tomography (CT) revealed bowel wall thickening with contrast enhancement at the cecum; however, no lymph node and organ metastases were found. As above, we performed laparoscopic ileocecal resection with D3 lymph node dissection. The postoperative course was uneventful, and he was discharged from the hospital on postoperative day 11. Histopathological findings were moderately differentiated adenocarcinoma which invaded the muscularis propria and serosa from the submucosa, while the adjacent serosa showed a highly diffuse proliferation of atypical cells with an irregular nuclear-to-cytoplasmic ratio. Besides, immunohistochemical staining findings were diffuse large B-cell lymphoma, and diffuse large B-cell lymphoma was coexistent with moderately differentiated adenocarcinoma. We treated the patient with cyclophosphamide, doxorubicin, vincristine, and prednisolone in combination with rituximab (R-CHOP therapy) during 3 months postoperatively. When the 8 courses had been completed, postoperative positron emission tomography-CT (PET-CT) confirmed complete response, and the disease control has been doing well. Malignant lymphoma of the colorectal region is relative rare, and the occurrence of synchronous lymphoma and adenocarcinoma of the colon is also rare. Furthermore, collision tumor by these different entities is very unusual. We presented here such a case. The accurate clinical determination of the dominant tumor and a close follow-up is required for proper treatment in these cases.
Additional Value of Preoperative Albumin for Surgical Risk Stratification among Colorectal Cancer Patients
Authors: Larson David W. , Abd El Aziz Mohamed A. , Perry William , D’Angelo Anne-Lise , Behm Kevin T. , Mathis Kellie L. , Grass Fabian
Published: March 2021

Background: BMI ≤18.5 kg/m2 and preoperative weight loss may lead to inaccurate assessment of nutritional status, given the increasing prevalence of obesity. The aim of this study was to assess whether clinical evaluation of malnutrition based on these parameters is sufficient to predict complications after colorectal cancer surgery. Materials and Methods: The American College of Surgeons-National Quality Improvement Program database was queried from 2005 to 2018. Patients undergoing elective colorectal cancer surgery were divided into 4 groups: (1) albumin <3.1 g/dL within 21 days of surgery, (2) European Society for Clinical Nutrition and Metabolism (ESPEN) 2 clinical parameters for malnutrition (≥10% loss of weight/6 months plus [BMI <20 kg/m2 if age <70 years OR BMI <22 kg/m2 if age ≥70 years]), (3) both aforementioned criteria, and (4) none of aforementioned criteria. Results: Of 82,280 patients, 5,932 (7.2%) had hypoalbuminemia <3.1 g/dL, 764 (0.9%) fulfilled clinical ESPEN 2 parameters, and 338 (0.4%) met both criteria. After adjusting for baseline confounders, patients in the hypoalbuminemia group had a higher risk of overall complications (odds ratio [OR] 1.92, p < 0.05 vs. OR 1.18 in the ESPEN 2 group, p < 0.05), major complications (OR 1.98, p < 0.05 vs. OR 1.20, p < 0.05), surgical complications (OR 1.77, 95% p < 0.05 vs. OR 1.1, p > 0.05), medical complications (OR 1.73, p < 0.05 vs. OR 1.16, p > 0.05), surgical site infection (OR 1.32, p < 0.05 vs. OR 0.86, p > 0.05), and prolonged hospitalization (OR 1.79, p < 0.05 vs. OR 1.22, p < 0.05). Patients who met both criteria were at highest risk. Conclusions: Preoperative measurement of serum albumin appears to be essential to identify patients at risk for complications after colorectal cancer surgery. Clinical evaluation through BMI and weight loss alone may underestimate surgery-associated risks in the USA.
Primary Small Intestinal Sarcomatoid Carcinoma: Report of a Rare Case and Literature Review
Authors: Karakuchi Nozomi , Yanagawa Senichiro , Kushitani Kei , Kodama Shinya , Takeshima Yukio , Sumimoto Kazuo
Published: March 2021

Sarcomatoid carcinoma (SC) is a rare malignant tumor with properties of both epithelial and mesenchymal carcinomas. SC has been reported in various organs, but the number of reports for each type is small. Small intestinal tumors make up about 3–6% of gastrointestinal malignancies. Discovering them in the early stage is rare and difficult, with anemia and/or abdominal pain as the major symptoms of small intestinal tumors. Primary small intestinal SC (SISC) is rare among small intestinal tumors, and currently very few cases have been reported in the literature. Previous studies have reported that neither chemotherapy nor radiotherapy improves the overall survival rate of patients with SISC, and the prognosis is extremely poor. Currently, surgical resection remains the only optimal therapeutic approach for SISC. Here, we present the case of a 90-year-old woman who had acute peritonitis due to perforation of a small intestinal tumor. She underwent emergency exploratory laparotomy and partial resection of the small intestine, including the tumor. The tumor was pathologically identified as a primary SISC with mesenteric lymph node metastasis. Subsequently, she had recurrence in the intra-abdominal area and lymph node metastasis anterior to the inferior vena cava and died 15 months after surgery without any additional treatment.
Clinical Effect of Two Fluoride Varnishes in Caries-Active Preschool Children: A Randomized Controlled Trial
Authors: Turska-Szybka Anna , Gozdowski Dariusz , Twetman Svante , Olczak-Kowalczyk Dorota
Published: March 2021

The prevention of dental caries in preschool children is a priority for dental services. The aim of the study was to investigate the caries-preventive effect of 2 fluoride varnishes in caries-active preschool children, and then compare the outcome with a non-varnish control group. After screening, 180 preschool children aged 36–71 months, with at least 1 noncavitated lesion, were enrolled and randomly allocated into 3 parallel groups, namely A: 1.5% ammonium fluoride varnish (Fluor Protector S), B: 5% NaF varnish (Duraphat), and C: professional tooth-cleaning. All children were recalled every third month for intervention and their parents were instructed to have them brush their teeth with a 1,000-ppm fluoride toothpaste twice daily. Caries were recorded at baseline and after 12 months by a calibrated examiner and the incidence was scored on noncavitated (d2) and cavitated (d3) level. We tested differences between the groups with the χ2 and two-sided t tests. One hundred and seventy-two children (95.6%) completed the trial and 56 (32.6%) and 35 (19.2%) developed new d2 and d3 lesions, respectively. Both varnishes reduced the incidence of caries compared with the control group, but there was no significant difference between group A and group B. Compared with group C, the relative risk for developing cavitated lesions was 0.39 (95% CI 0.22–0.62) in group A and 0.26 (95% CI 0.14–0.50) in group B. The total prevented fraction (Δd2d3mft) for group A and group B was 19.9 and 22.5% (p < 0.05), respectively. No adverse effects were observed or reported during the study period. In conclusion, the 2 fluoride varnishes demonstrated an equal capacity to reduce the incidence of caries in caries-active preschool children over a 12-month period in comparison with a control group.
Breastfeeding and Childhood Dental Caries: Results from a Socially Diverse Birth Cohort Study
Authors: van Meijeren-van Lunteren Agatha W. , Voortman Trudy , Elfrink Marlies E.C. , Wolvius Eppo B. , Kragt Lea
Published: March 2021

Previous studies showed that prolonged breastfeeding increases the risk of caries. However, the observed associations were mainly based on non-European populations, and important confounding and mediating factors like socioeconomic position (SEP) and diet were often neglected. The aim of this study was to investigate the role of breastfeeding and bottle-feeding practices on dental caries during childhood while accounting for SEP, ethnic background, and sugar intake. This study was part of the Generation R Study, a prospective multiethnic cohort study conducted in Rotterdam, The Netherlands. In total, 4,146 children were included in the analyses. Information about feeding practices was derived from delivery reports and questionnaires during infancy. Caries was measured via intraoral photographs at the age of 6 years and defined as decayed, missing, and filled teeth (dmft). Negative binomial hurdle regression analyses were used to study the associations between several infant feeding practices and childhood caries. The prevalence of dental caries at the age of 6 years was 27.9% (n = 1,158). Prolonged breastfeeding (for >12 months) was associated with dental caries (OR 1.35, 95% CI 1.04–1.74) and the number of teeth affected by dental caries (RR 1.27, 95% CI 1.03–1.56). Furthermore, nocturnal bottle-feeding was associated with dental caries (OR 1.52, 95% CI 1.20–1.93). All associations were independent of family SEP, ethnic background, and sugar intake. Results from this Dutch cohort study confirmed the previously observed associations between prolonged breastfeeding and nocturnal bottle-feeding and the increased risk of childhood dental caries, even after proper adjustments for indicators of SEP, ethnic background, and sugar intake. Future studies are encouraged to elaborate further on possible explanations for the observed relationships. Healthcare professionals should be aware and advise caregivers about the potential risk of prolonged breastfeeding on caries development by applying the current recommendations on breastfeeding, oral hygiene, and feeding frequency.
Post-Chemotherapy Rebound Thymic Hyperplasia Mimicking Relapse in Breast Implant-Associated Anaplastic Large Cell Lymphoma: A Case Report
Authors: Lazaro-Garcia Alberto , Lacalle-Gonzalez Carlos , Santonja Carlos , Rodríguez-Pinilla Socorro-María , Cornejo José-Ignacio , Morillo Daniel
Published: March 2021

Introduction: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an unusual form of T-cell non-Hodgkin lymphoma. Surgical management is essential; however, adjuvant therapy is recommended for advanced stages of cancer. Case Presentation: A 40-year-old woman with textured silicone implants placed 7 years earlier, presented with breast nodules. Physical examination and computed tomography (CT) revealed a left parasternal mass, 2 left-breast nodules, and axillary lymphadenopathies. A soft-tissue lesion in the anterior mediastinum consistent with thymic remnants was detected. BIA-ALCL was diagnosed based on ultrasound-guided core biopsies of an axillary lymph node and a breast nodule. She underwent total bilateral capsulectomy and received anthracycline-based adjuvant chemotherapy. End-of-treatment positron emission tomography-computed tomography (PET-CT) scan at 4 months showed no evidence of disease, except for the persistence of the mediastinal lesion (Deauville score 4). Three months later, a new PET-CT scan showed enlargement of the lesion and increased radiotracer uptake, suggesting metabolic progression. A mediastinal biopsy was performed and rebound thymic hyperplasia (RTH) was observed in the histopathologic study. Once complete remission (CR) was achieved, the patient was followed up continually and has shown no signs of relapse to date. Conclusions: Further studies are required to determine the best adjuvant therapy for advanced BIA-ALCL. RTH may be suspected when thymic enlargement without the involvement of other areas is observed in patients with cancer. Mediastinal biopsy is mandatory to rule out relapse.
Latinos & Racism in the Trump Era
Authors: Canizales Stephanie L. , Vallejo Jody Agius
Published: March 2021

This essay examines the roots, causes, and effects of racism experienced by Latinos in the Trump era. We argue that Trump and his administration were not the origin of Latinos' experiences of racism, but his rise to power was, in part, derived from Latino racialization. Preexisting politics of Latino immigration, Whites' fear of loss of status due to demographic shifts, and historical and contemporary processes of racializing Latinos were seized by the Trump administration and made central features of his renegade presidential campaign and policy agenda. White nationalist racism became the defining feature of the Trump presidency, making Latinos' heightened experiences of racism, and the relegitimization of overt White nationalism, one of its lasting legacies.
La philosophie au tournant des années 1940 : Étienne Gilson
Authors: De Libera Alain
Published: March 2021

L’article est consacré à l’histoire des chaires de philosophie du Collège entre 1921 et 1951, considérée à partir du double échec subi en 1941 par le médiéviste Etienne Gilson, au moment de repourvoir la chaire de « Philosophie » définie pour Édouard Le Roy en 1921 après le départ de Henri Bergson. Sur la base d’un arbre généalogique de la philosophie au Collège de France depuis 1542, l’article restitue les enjeux des deux phases du duel entre Gilson et son principal opposant Mario Roques : a) le maintien de l’intitulé de Édouard Le Roy contre la proposition gilsonienne : Histoire des idées philosophiques dans la France moderne, b) l’élection du spiritualiste Louis Lavelle contre le philosophe psychologue Maurice Pradines, à la chaire de philosophie. L’article analyse les différents biais (statut de la philosophie à l’université, dans les lycées et collèges, laïcité, statut de la métaphysique, situation politique), affectant l’affrontement entre philosophie et histoire de la philosophie, lieu commun rhétorique des débats idéologiques depuis 1874.
Rome au Collège de France entre la Révolution et le XXe siècle. Une évolution rapide
Authors: Scheid John
Published: March 2021

Parmi les nouvelles chaires créées au Collège de France au XIXe siècle dans le domaine des langues classiques, apparurent en 1861 et en 1877 l’Épigraphie latine et l’Épigraphie grecque. Il s’agissait de création de chaires. Pour la est conservé un dialogue entre l’Institut, le Collège de France et le ministère de l’Instruction publique, avec l’approbation de l’Empereur. À l’arrière-plan de la création ministérielle, on devine l’ombre de Philippe Le Bas et du projet de Corpus des inscriptions latines organisé selon les normes définies par Theodor Mommsen, qui avait réuni du temps du ministère d’Abel Villemain des Français, des Allemands et des Italiens. Quant à la chaire d’Épigraphie grecque, la seconde, les lettres de justification de sa création en apportent la preuve : elles décrivent l’activité épigraphique telle que les concepteurs du Corpus d’inscriptions berlinois l’imaginaient.
Systèmes ou pensée ? L’histoire de la philosophie en question au Collège de France (1951)
Authors: Bianco Giuseppe
Published: March 2021

Cet article cherche à éclairer l’élection de Martial Gueroult (1891-1976) à la chaire d’Histoire et technologie des systèmes philosophiques en 1951, et, indirectement, le succès de son approche « structurale » de l’histoire de la philosophie. Ceux qui occupaient des rôles clés dans la gestion de l’économie disciplinaire des sciences humaines ne devaient pas contredire dans leur travaux les axiomes qui avaient réglé la pratique de l’histoire de la philosophie depuis le début du XIXe siècle tout en faisant montre d’innovation dans ce champ. Dans un premier temps nous résumons la méthode historiographique proposée par Gueroult ; un deuxième temps l’inscrit dans une tradition d’historiographie de la philosophie ; le troisième temps situe sommairement la pratique de l’histoire de la philosophie au Collège de France et à la Sorbonne ; dans de quatrième et cinquième temps nous décrivons les rapporteurs et les candidats lors de l’élection au Collège de France, et les pièces pertinentes ; enfin nous considérons les stratégies adoptées pendant la campagne qui ont pu déterminer le résultat de l’élection.
Molecular evidence for deeper diversity in Australian Tanypodinae (Chironomidae): Yarrhpelopia and related new taxa
Authors: CRANSTON PETER S. , KROSCH MATT , BAKER ANDREW M.
Published: March 2021

The diversity and endemism of Australian Tanypodinae (Diptera: Chironomidae) has been unclear from morphological comparisons with well-grounded northern hemisphere taxonomy. As part of a comprehensive study, here we focus on one of the few described endemic genera, Yarrhpelopia Cranston. Extensive and intensive new sampling and newly-acquired molecular data provides clarity for the type species, Yarrhpelopia norrisi Cranston and allows recognition of congeners and potential sister group(s). We describe Yarrhpelopia acorona Cranston & Krosch sp. n., and we recognise a third species from Western Australia, retaining an informal code ‘V20’ due to inadequate reared / associated material for formal description. We recognise a robust clade Coronapelopia Cranston & Krosch gen. n., treated as a genus new to science for two new species, Coronapelopia valedon Cranston & Krosch sp. n. and Coronapelopia quadridentata Cranston & Krosch sp. n., from eastern Australia, each described in their larval and pupal stages and partial imaginal stages. Interleaved between the independent new Australian clades Yarrhpelopia and Coronapelopia are New World Pentaneura and relatives, that allow a tentative inference of a dated gondwanan (austral) connection. Expanded sampling indicates that Y. norrisi, although near predictably present in mine-polluted waters, is not obligate but generally indicates acidic waters, including natural swamps and Sphagnum bogs. The inferred acidophily, including in drainages of mine adits, applies to many taxa under consideration here.
11. Highly Available Dissertations
Authors: Tagliaferri Lisa
Published: March 2021

Lisa Tagliaferri reinforces the need for academic work to reach a wider audience using her own dissertation as a case study. In ‘Highly Available Dissertations: Open Sourcing Humanities Scholarship’, not only does Tagliaferri advocate for open source, hers was also the first chapter offered as a preprint to this collection, via MIT’s database. Her chapter describes open source, open access, and Creative Commons before offering suggestions for stakeholders to consider when navigating various levels of access.
12. The Digital Thesis as a Website
Authors: Masure Anthony
Published: March 2021

Anthony Masure’s approach deepens the notion of his dissertation work’s readability, working from inside France’s academic system. Noting the technical hurdles of constantly updating a webpage, for example, he designs his PhD-thesis website by cleaning HTML code and without using a CMS, thus aiming for a ‘true’ version of his dissertation that, in fact, supersedes the version he submitted to obtain his degree. Ultimately, Masure leads us back to Tim Berners-Lee by advocating for sharing knowledge without borders and critically engaging with the potentially limiting affordances of specific media prescribed for knowledge production.
15. Lessons from the Sandbox
Authors: Williams Christopher
Published: March 2021

Christopher A. Williams explores the deeper layers of web design to discover the communicative potential of ‘sticky web galleries’ for the multimodal and broad public dissemination of improvisation in music. He describes in great detail the collaborative process necessary to design his thesis, complete with paths and multimedia files that align with musical knowledge, beyond linear text. As a team, he and his collaborator arrive at a site that ‘as a whole functions as a sort of meta-score for improvisers’. At the same time, the thesis becomes not only a milestone within a research path, it also turns into a resource for practitioners outside of the usually closed publication loop as a ‘living meta-work.’
Negotiating Mental Health During the COVID-19 Pandemic: Performing Migrant Domestic Work in Contentious Conditions
Authors: Kaur-Gill Satveer , Qin-Liang Yeo , Hassan Samira
Published: March 2021

Migrant domestic work is performed in precariously (im)mobile working conditions that mark the subaltern body in a state of constant lived experience with and in strife. In Singapore, the structural context of hire amplifies conditions of servitude, indebtedness, and subalternity that have implications for mental health. This study documents mental health narratives by migrant domestic workers during the COVID-19 pandemic, registering how mental health is negotiated amid dissension in the performance of precarious labor. While functional employment structures enabled and empowered well-being, dysfunctional structures disrupted mental health meanings, creating layers of constant contention for domestic workers to broker, limiting opportunities for mental health and well-being. Narratives gathered indicate systemic mental health precarities tied to workplace dysfunctions.
Collective sensemaking in the local response to a grand challenge: Recovery, alleviation and change-oriented responses to a refugee crisis
Authors: van der Giessen Mark , Langenbusch Christina , Jacobs Gabriele , Cornelissen Joep
Published: March 2021

Grand societal challenges such as forced displacement are extreme and complex issues that are challenging to individuals and might seem insurmountable. How do local actors make sense of, position themselves in and act on such challenges? We conducted a case study of the collective sensemaking narratives of 71 actors involved in the refugee crisis on Lesbos, Greece. We elaborate how actors make sense of their role in the local response to this grand challenge and explain why some ultimately chose to cooperate to address the plight of refugees while others distributed tasks or avoided responding altogether. We identify three collective sensemaking narratives that actors use to validate such action strategies aimed at alleviation, personal recovery or structural change; and as characterized by different forms of interaction and emergent collective sensemaking. We contribute with our article to the study of responses to grand challenges by showing how a collective sensemaking framework can be used to understand local responses. We also contribute to extant theorizing on collective sensemaking by showing how actors make sense of grand challenges through interactions with other actors and how their narratives inform individual and collective action.
Acoustic and Perceptual Characteristics of Mandarin Speech in Gay and Heterosexual Male Speakers
Authors: Geng Puyang , Gu Wentao
Published: March 2021

This study investigated acoustic and perceptual characteristics of Mandarin speech produced by gay and heterosexual male speakers. Acoustic analysis of monosyllabic words showed significant differences between the two groups in voice fundamental frequency (F0), F1 of low vowel, and duration of aspiration/frication in consonants. The acoustic patterns on F0, formants, and center of gravity as well as spectral skewness of /s/ differed from those reported for Western languages like American English, which could be interpreted from a sociopsychological point of view based on different acceptability of gay identity in the two societies. The results of a perceptual experiment revealed significant but weak correlations between the acoustic parameters and the score of perceived gayness, which was significantly higher on gay speech than on heterosexual male speech. Although the observed F0 and F1 patterns in Mandarin gay speech were opposite to the stereotype of gayness, gay identity can still be identified to some extent from speech due to the existence of other acoustic cues such as a longer fricative duration, which is not a stereotype of gayness but has been consistently observed in Mandarin and Western languages.
State-Led Gentrification and Self-Respect
Authors: Wells Katy
Published: March 2021

Gentrification is a global and highly controversial issue. This article develops an account of what can be troubling, specifically, about state support for gentrification processes. Recent research points to the fact that gentrification processes are being used by policy-makers in many parts of the world as tools for urban ‘renewal’ or transformation. However, it is claimed that this is often at the cost of badly off residents of these areas. I argue that where the state supports or encourages gentrification processes that either (a) impose non-trivial costs on badly off residents of gentrifying areas or (b) fail to benefit these residents in certain ways, the state disrespects these residents by failing to show due regard for their interests. In doing so, it threatens their self-respect. Having made this argument, I also consider how certain kinds of state investment once gentrification processes have occurred can threaten the self-respect of original residents.
Teacher Implemented Communal Learning in Math: Boosting Learning with African American Elementary Students
Authors: Coleman Sean T. , Hurley Eric A. , Boykin A. Wade
Published: March 2021

The current study examined lasting learning effects of communal contexts for 124 African American third and fourth-grade students using a mathematics fractions unit with students’ regularly assigned teachers. Teachers in two experimental conditions received training on implementing communally or individually structured fractions curricula, and a naturalistic control was included whose participants did not receive the intervention. Findings revealed that students in the communal condition outperformed those who learned individually, and students in both intervention conditions outperformed those in the naturalistic control group. Survey of communal home-socialization obtained a relationship with identifying fractions performance. Implications for facilitative effects of culturally informed learning environments and teacher training toward enhanced academic achievement are discussed.
Computed Tomography Evaluation of Unilateral Chronic Maxillary Sinusitis With Osteitis
Authors: Che Zigang , Zhang Qingxiang , Zhao Pengfei , Lv Han , Ding Heyu , Li Jing , Wang Hao , Zhang Peng , Ji Hongbo , Zou Caiyun , Wang Zhenchang
Published: March 2021

Background:

Computed tomography (CT) is the preferred noninvasive method for the evaluation of osteitis in chronic sinusitis. Some scholars believe that the bone changes associated with chronic sinusitis always show high attenuation (high density) and are positively correlated with the severity of the disease. However, sinus bone remodeling is a complex process that may cause high or low attenuation. There have been few reports on the spread of osteitis. Therefore, additional research on sinus CT is necessary.

Objective:

To observe bony changes in chronic maxillary sinusitis (CMS) by CT and reveal the mechanism.

Methods:

A retrospective study was conducted in 45 patients with unilateral CMS with bony changes in the sinus walls. The patients’ clinical data and CT results were analyzed and compared between the affected and normal sides. We propose the location, involvement, attenuation, and thickness method to evaluate CMS with osteitis.

Results:

Of the 45 patients, 40 (88.9%), 2, 12, and 7 had posterior external, medial, anterior, and superior lesions, respectively. The nasal region, sphenoid bone, palatine bone, and zygomatic arch were involved in 3, 12, 8, and 18 (40%) patients, respectively. Computed tomography indicated high attenuation in 30 (75.0%) and low attenuation in 10 (25.0%) patients; 6 (15.0%) showed new bone marrow cavities. The bone thickness was significantly different between the affected and normal sides in 40 patients ( P < .001), including members of both the high- and low-attenuation groups (high-attenuation group: P < .001; low-attenuation group: P < .01). However, there was no significant difference in the thickness of the affected side between the high- and low-attenuation groups ( P > .05).

Conclusions:

Chronic rhinosinusitis with bony changes may occur in the maxillary sinus walls and spread to adjacent bones. Both increased and decreased attenuation may occur in these circumstances. Analyzing the CT features of bone changes in unilateral CMS can improve the accuracy of disease diagnosis.
Development and Testing of the Quality Improvement Self-efficacy Inventory
Authors: Baernholdt Marianne , Jones Terry L. , Anusiewicz Colleen V. , Campbell Caitlin Marley , Montgomery Aoyjai , Patrician Patricia A.
Published: March 2021

Quality improvement is paramount for patient safety. Leading change for quality improvement requires nurses with knowledge and skills beyond the clinical management of patients. In this study, staff nurses working in hospitals throughout Alabama were asked via an online survey to rate their quality improvement knowledge and skills using the new 10-item Quality Improvement Self-Efficacy Inventory (QISEI) and their perceptions of the nursing work environment using the Practice Environment Scale of the Nursing Work Index. Nurses ( N = 886) rated the basic quality improvement items higher than the more advanced items. Several nurse characteristics and the nursing work environment were associated with nurses’ ratings of their quality improvement knowledge and skills. Educators and administrators in health care organizations can use QISEI to gauge their nurses’ knowledge and skills and then develop continuous professional development opportunities aimed at improving quality and safety competencies.
Generational Differences in Nurses’ Intention to Leave
Authors: Koehler Thomas , Olds Danielle
Published: March 2021

There are many studies about nurses’ intention to leave their jobs and contributing factors. However, there is a lack of research about generational differences in nurses’ intention to leave. This evidence may help with workforce planning and targeting specific generations of nurses with retention interventions. Using the National Database of Nursing Quality Indicators 2018 Annual Registered Nurse Survey, we used descriptive statistics and multivariate logistic regression to examine the prevalence of and reasons for nurses’ intention to leave in the next year by generational age group. Our sample included 207,636 hospital nurses from across the United States. We found that 21% of nurses ( n = 44,082) reported intention to leave. When comparing generations, there were differences in intention to leave, as well as differences in potentially preventable, career advancement, and personal intention to leave reasons. Workload/staffing was a common reason across generations, indicating that certain interventions may be applicable regardless of generation.
Prospective comparative study evaluating the role of flavonoids after endovenous thermal ablation
Authors: Karathanos Christos S , Batzalexis Konstantinos , Nana Petroula , Spanos Konstantinos , Kouvelos George , Rousas Nikolaos , Giannoukas Athanasios
Published: March 2021

Objectives

The aim of our study was to evaluate the role of flavonoids in the improvement of post-operative symptoms after endovenous thermal ablation (EVTA).

Methods

A prospective comparative study of 120 consecutive patients undergoing EVTA of the greater saphenous vein associated with phlebectomies was undertaken. Patients were grouped in those receiving micronized purified flavonoid fraction (MPFF- 60 patients) agent 500 mg Bid 7 days pre- and 30 days post- operatively (MPFF group) and those in the control group (60 patients) who did not. Demographics, intra-operative details, Clinical –Etiology- Anatomy- Pathophysiology (CEAP) clinical class, 10-cm Visual Analog Scale (VAS) for pain, Venous Clinical Severity Score (VCSS) and Chronic Venous Insufficiency Quality-of-Life Questionnaire (CΙVIQ-20) were recorded. Primary outcome was the postoperative pain assessement using the VAS scale and CIVIQ pain score. Secondary outcomes included assessement of VCSS and CΙVIQ-20 scores.

Results

There were no significant differences between the groups regarding demographics, clinical and procedural characteristics. Patients in MPFF group reported significantly lower VAS pain levels than control group at 7- (−3.6 ± 1.2 vs −2.7 ± 1.9, p < .0001) and 30- post-operative day (−4.9 ± 0.1 vs −4.2 ± 1, p < .0001). MPFF group also showed better outcome in terms of CIVIQ pain score at 7- (−3.7 ± 1.3 vs −3.5 ± 1.8, p = .008) and 30- post-operative day (−5.3. ± 1.1 vs −4.4 ± 1, p = .017). Both groups showed a significant improvement in VAS pain score (p = .047), global CIVIQ-20 (p = .009) and VCSS (p = .008) at 7- and 30-days post-operatively.

Conclusions

Administration of flavonoids in patients undergoing EVTA associated with phlebectomies reduces pain by a small amount during early postoperative period.
Perinatal Depression Educational Training for Graduate Nursing Students
Authors: Long Molly M. , Cramer Robert J. , Leiferman Jenn A. , Bennington Linda K. , Paulson James F.
Published: March 2021

The purpose of this study was to implement and assess an educational intervention for nursing students pertaining to perinatal depression (PD) screening and treatment. A single group (n = 59), repeated-measures design (i.e., pre- and post-intervention assessments) was used to assess the impact of an online intervention. Demographics, Theory of Planned Behavior constructs, intention to screen and treat PD, and PD-related knowledge were tested. The intervention resulted in positive gains in PD-related perceived behavioral control (PBC), attitudes, subjective norms, knowledge, intention to screen and treat PD, and perceived importance of screening and treating PD from pre- to post-intervention. PBC demonstrated a small-to-moderate positive association with perceived importance of screening and treating PD at post-intervention. Results from the current study suggest that the PD online educational intervention is effective in improving participants’ PD-related PBC, attitudes, subjective norms, knowledge, and intention to screen and treat PD.
Qualitative Analysis of a Teacher’s Reflections on Medical Students Using Public Narratives to Promote Health
Authors: Jaimes-Peñuela Claudia Liliana , Duran-Cardenas Yenny Catalina , Hernandez-Rincon Erwin Hernando , Correal-Muñoz Camilo Alejandro
Published: March 2021

A qualitative, inductive content analysis was done to explore a teacher's reflections on the experiences of a team of medical students using public narratives to promote health within a Colombian university. Data were collected from the teacher's written reflective journal and an academic report, the latter, submitted by the medical students. ‘Being mobilized’ emerged as an overarching category. The experiences were described in three interrelated categories: team involvement, barriers and countering these barriers. In terms of team involvement, students were motivated, committed, connected with people and frustrated. On the other hand, barriers such as doubts and discomfort remarked, and finally these barriers were countered through training, practice and teamwork. As conclusion, the public narrative framework has changed the way medical students think about how to mobilize people for health promotion in a university. Narrative approaches are gaining strength as sources of motivation to support the adoption of healthy behaviors.
Dance Across Cultures: Joint Action Aesthetics in Japan and the UK
Authors: Monroy Ernesto , Imada Toshie , Sagiv Noam , Orgs Guido
Published: March 2021

Western European and East Asian cultures show marked differences in aesthetic appreciation of the visual arts. East Asian aesthetics are often associated with a holistic focus on balance and harmony, in contrast to Western aesthetics, which often focus on the expression of the individual. In this study, we examined whether cultural differences also exist in relation to the aesthetics of dance. Japanese and British participants completed an online survey in which they evaluated synchronous and asynchronous dance video clips on eight semantic differential scales. We observed that the aesthetics of group dance depend on cultural background. Specifically, British participants preferred asynchronous over synchronous dance whereas Japanese participants equally liked synchronous and asynchronous dance movement. For both cultures, preferences were based on distinct semantic associations with movement synchrony. We argue that cultural differences in aesthetic perception of group dance relate to the culturally specific social signals conveyed by unison movement.
High serum levels of CA 19-9 and CYFRA21-1 caused by renal pelvis urothelial carcinoma: a report of two cases
Authors: Yin Guolin , Zhang Miaomiao , Zhao Bing , Yang Zaixing
Published: March 2021

Carbohydrate antigen 19-9 (CA19-9) and cytokeratin 19 fragment (CYFRA21-1) are widely used as tumor markers in clinical practice and are increased in many neoplasms. However, although increased serum CA19-9 levels have been found in some Japanese patients with renal urothelial carcinoma (UC), they have not been detected in patients from other countries or regions, and increased serum CYFRA21-1 levels haves not been reported in patients with renal UC. We analyzed serum CA19-9 and CYFRA21-1 levels in two patients with renal UC and monitored the changes in levels during postoperative follow-up. Both cases with renal pelvis UC had high levels of serum CA19-9 and CYFRA21-1, which decreased to within normal ranges after successful surgery, suggesting a causal relationship between renal UC and increased serum CA19-9 and CYFRA21-1. Because serum levels of CA19-9 and CYFRA21-1 are increased in many neoplastic diseases, they may not be reliable tumor markers for the screening and diagnosis of renal UC. However, they may be useful noninvasive indicators for assessing treatment effects in patients with renal pelvis UC with elevated pretreatment serum CA19-9 or CYFRA21-1.
From coercion to cooperation: Urban governance and evolving modes of control in a Beijing village
Authors: Kim Jaesok
Published: March 2021

This article analyzes evolving urban governance in contemporary China, highlighting contradictory outcomes originating from the coexistence of the technologies of pervasive control, socialist legacies of urban entitlements, and neoliberal strategies of self-government. Based on fieldwork among low-income migrant workers in a village located on Beijing's outskirts, I investigate how the grassroots administrative practices justified the continuing privileges of local residents and discrimination against newcomers, while the evolving governance projects a better future for every individual who is willing to exert themselves. The 2014 implementation of a Social Credit System was critical for this political agenda. It offered rewards and imposed punishments corresponding to the level of reliability indicated by credit scores, thereby urging migrants to “responsibly” manage their lives. The combination of high-tech surveillance and social credit demonstrates that the notion of “market socialism”, combined with neoliberal practices, has created a new system of social control in 21st-century China.
I-RIPRAP Computer Vision Software for Automated Size and Shape Characterization of Riprap in Stockpile Images
Authors: Huang Haohang , Luo Jiayi , Qamhia Issam , Tutumluer Erol , Hart John M. , Stolba Andrew J.
Published: March 2021

Riprap rocks and large-sized aggregates have been used extensively in geotechnical and hydraulic engineering applications to serve as a key component for erosion/sediment control and scour protection. Toward sustainable and reliable use of riprap rocks, an efficient and accurate method to characterize the size and shape properties is deemed necessary. Current state-of-the-practice methods mostly assess riprap properties with labor-intensive and time-consuming inspection routines that involve manual size and weight measurements. Recent advances in the field of computer vision have been leveraged in this paper to apply deep learning for the development of an innovative image analysis tool for quantitative and efficient riprap characterization. Based on the single-aggregate and stockpile-aggregates studies conducted on this topic, this paper introduces a newly developed computer program, named I-RIPRAP, for the advanced characterization of aggregate size and shape from images of riprap stockpile(s). The essential features and software workflow, as well as the function and mechanism of each module, are described and discussed in detail. In addition to the deep learning methods for segmentation, I-RIPRAP also improves the morphological analyses with a volume/weight estimation module and a riprap category reference module to generate useful results that can facilitate quality assurance/quality control tasks. The I-RIPRAP software is envisioned to serve as an efficient and innovative tool for field and in-place evaluations of riprap and large-sized aggregates.
Alternative Regression Model Structure for the HCM-6 Equal-Capacity Passenger Car Equivalency Methodology
Authors: Hurtado-Beltran Antonio , Rilett Laurence R.
Published: March 2021

In the current version of the Highway Capacity Manual (HCM-6), equal-capacity passenger car equivalencies (EC-PCEs) are used to account for the effect of trucks for capacity analyses. The EC-PCEs for freeway segments were estimated using a microsimulation-based methodology where the capacities of the mixed-traffic and car-only flow scenarios were modeled. A nonlinear regression (NLR) model was used to develop capacity adjustment factor (CAF) models using the microsimulation data as input. The NLR model has a complex model structure and includes 15 model parameters. It is argued in this paper that simpler regression models could provide comparable results. This would allow CAF and EC-PCE equations to be used directly in the HCM-6 rather than tables. It would also allow for the development of new regression models for exploring new technologies such as connected and automated vehicles (CAVs). The objective of this paper was to develop alternative and simpler regression models of CAFs needed to derive the EC-PCE values in the HCM-6 methodology for freeway and multilane highway segments. It was found that simpler regression models provided similar results as those obtained with the current NLR model. Additionally, it was found that the current NLR model may not be adequate for analyzing CAV traffic conditions. If the HCM-6 EC-PCE methodology is expected to be used to analyze traffic conditions beyond the scope of the HCM-6, it is important to perform a deeper assessment of the form and error of the regression models used in fitting the simulated and estimated data.
Mathematical models for shear-induced blood damage based on vortex platform
Authors: Mei Xu , Zhong Min , Ge Wanning , Zhang Liudi
Published: March 2021

Non-physiological shear stress in Ventricular Assist Device (VAD) is considered to be an important trigger of blood damage, which has become the biggest shackle for clinical application. The researches on blood damage in literature were limited to qualitative but did not make much quantitative analysis. The purpose of this study was to investigate the quantitative influence of two flow-dependent parameters: shear stress (rotational speed) and exposure time on the shear-induced damage of red blood cells and von Willebrand Factor (vWF). A vortex blood-shearing platform was constructed to conduct in vitro experiments. Free hemoglobin assay and vWF molecular weight analysis were then performed on the sheared blood samples. MATLAB was used for regression fitting of original experimental data. The quantitative correlations between the hemolysis index, the degradation of high molecular weight vWF and the two flow-dependent parameters were found both following the power law model. The mathematic models indicated that the sensitivity of blood damage on red blood cells and vWF to exposure time was both greater than that of shear stress. Besides, the damage of vWF was more serious than that of red blood cells at the same flow condition. The models could be used to predict blood damage in blood-contacting medical devices, especially for the slow even stagnant blood flow regions in VAD, thus may provide useful guidance for VAD development and improvement. It also indicated that the vortex platform can be used to study the law of blood damage for the simple structure and easy operation.