bluuebunny/crossref_metadata_2025 huggingface dataset:
The stability increase of α-amylase enzyme from Aspergillus fumigatus using dimethyladipimidate
Authors: Yandri Yandri , Nurmala Nurmala , Suhartati Tati , Satria Heri , Hadi Sutopo
Published: April 2022

This study’s purpose is to improve the α-amylase enzyme’s stability from Aspergillus fumigatus applying dimethyladipimidate (DMA). It was conducted in different stages, including production, isolation, purification, modification, and the characterization of native and modified enzymes by the DMA addition. The enzyme activity was specified using the Fuwa and Mandels methods, while the protein level was conducted by the Lowry method. The results indicated that the native enzyme contains a specific activity of 7010.42 U/mg, with an increase of 7.8 times than the crude extract, which contains 904.38 U/mg. Meanwhile, the native enzyme contains an optimum pH of 5 at 55 °C, with residual activity of 17.17% after 60 min of incubation at 55 °C and a half-life of 25.86 min. After the DMA addition with 0.5, 1, and 1.5% concentration, the enzymes had 5.5 optimum pH and 65 °C temperature. Meanwhile, after 60 min of incubation at 65 °C, the modified enzymes had 54.17, 46.18, and 34.44% of residual activity, and 85.55 58.25 and 37.46 min of half-lives, respectively. This showed that the addition of DMA to the native α-amylase from A. fumigatus increased the stability of the modified enzymes by 1.5–3.3 times than the native enzyme.
Weniger ist mehr: Glas in der Sântana de Mureş-Černjachov Kultur (Kreis Vaslui/Ostrumänien)
Authors: Grumeza Lavinia
Published: April 2022

In diesem Beitrag werden die Glasgefäße und Mosaikperlen mit Gesichtsmasken aus Fundorten der Sântana de Mureş-Černjachov Kultur in Ostrumänien, Kreis Vaslui, vorgestellt. In der für Vaslui angelegten Datenbank (angelehnt an die Systematik im Corpus der römischen Funde im europäischen Barbaricum) sind 84 Glasgefäße unterschiedlicher Typen verzeichnet, datierend vom Ende des 3. bis zum Beginn des 5. Jahrhunderts n. Chr. (bes. der Typ Kowalk und konische Becher mit Facettierung). Im Gräberfeld von Bârlad-Valea Seacă fand sich die bislang größte Anzahl an Glasgefäßen (50 %). Nur indem zukünftig umfassende Fundkataloge für Glaswaren auch für die Nachbarregionen erarbeitet werden, wird man einen Überblick über die sozioökonomischen Beziehungen, die Technologien und den Handel in der gesamten Region erhalten.
“My Dear Fatherland, When Will You Ever Flourish?” Recent Historical Literature on Georgia
Authors: Hausmann Guido
Published: April 2022

The history of Georgia and the entire South Caucasus or Transcaucasia is a heavily marginalised field in international historical scholarship. This book review essay identifies and discusses major trends in recent publications on the modern history of Georgia in order to improve the chances of its integration into larger historical contexts and debates.
NEMATOMAS MOBILUMAS IR ĮKASDIENINTOS TECHNOLOGIJOS. JOSVAINIŲ MIESTELIO ATVEJIS
Authors: Dambrauskaitė Ernesta
Published: April 2022

The article discusses the question of whether everyday life in an ordinary small Lithuanian town is indeed inactive, stagnant, empty and immobile. Mobility in everyday life is analysed through the habits of locals in the town of Josvainiai, and relations with the nearest cities and relatives living abroad. In analysing mobility, the main focus is on areas of everyday life such as work, consumption, communication and leisure. The article analyses data from a field study carried out in Josvainiai from July 2019 to January 2020.
LIETUVIŲ KALBOS ENTOMONIMAI: NOMINACIJA IR MOTYVACIJOS MODELIAI
Authors: Šalaviejūtė Žydrūnė
Published: April 2022

The article presents an analysis of Lithuanian folk entomonyms (insect names). The methodological approach is based on complex linguistic research, where semasiological and onomasiological aspects are combined. The main sources of empirical material are the LKŽe and 13 dialect dictionaries. Detailed analysis of lexicographical sources helped to establish the boundaries of the thematic group of entomonyms. Entomonyms are studied as the result of a nomination and motivation process. The analysis helped to determine the relationship between motivated and unmotivated members of the thematic group, the dominant nomination types, ways, instruments, the most important features of motivation, and the variety of models of motivation.
SMART: An Open-Source Extension of WholeBrain for Intact Mouse Brain Registration and Segmentation
Authors: Jin Michelle , Nguyen Joseph D. , Weber Sophia J. , Mejias-Aponte Carlos A. , Madangopal Rajtarun , Golden Sam A.
Published: April 2022

Mapping immediate early gene (IEG) expression across intact mouse brains allows for unbiased identification of brain-wide activity patterns underlying complex behaviors. Accurate registration of sample brains to a common anatomic reference is critical for precise assignment of IEG-positive (“active”) neurons to known brain regions of interest (ROIs). While existing automated voxel-based registration methods provide a high-throughput solution, they require substantial computing power, can be difficult to implement and fail when brains are damaged or only partially imaged. Additionally, it is challenging to cross-validate these approaches or compare them to any preexisting literature based on serial coronal sectioning. Here, we present the open-source R package SMART (Semi-Manual Alignment to Reference Templates) that extends the WholeBrain R package framework to automated segmentation and semi-automated registration of intact mouse brain light-sheet fluorescence microscopy (LSFM) datasets. The SMART package was created for novice programmers and introduces a streamlined pipeline for aligning, registering, and segmenting LSFM volumetric datasets across the anterior-posterior (AP) axis, using a simple “choice game” and interactive menus. SMART provides the flexibility to register whole brains, partial brains or discrete user-chosen images, and is fully compatible with traditional sectioned coronal slice-based analyses. We demonstrate SMART’s core functions using example datasets and provide step-by-step video tutorials for installation and implementation of the package. We also present a modified iDISCO+ tissue clearing procedure for uniform immunohistochemical labeling of the activity marker Fos across intact mouse brains. The SMART pipeline, in conjunction with the modified iDISCO+ Fos procedure, is ideally suited for examination and orthogonal cross-validation of brain-wide neuronal activation datasets.
Pardon the Interruption
Authors: Miller Paul Allen
Published: April 2022

The Timaeus is a muthos that attempts to imagine a logos of the cosmos. Like the demiurge, readers are to be mimetic artists, poets (Tim. 28c3), who move constantly between the intelligible essences and their likenesses in the world of appearance, experience, and becoming, occupying a third register that is neither and both (28a6–b2). The cosmology of the Timaeus is both a likely story and an allegory of its own failure. It takes place within the nonspace of the khōra, a realm accessible only through bastard reasoning that we can perceive only as if in a dream. The Timaeus is an unfinalizable logos in which each moment of positing is also a moment of irony and interrogation, of simultaneous acceptance and active separation, of choric space.
Bimbingan Agama Dalam Mengatasi Kecemasan Pada Lansia Melalui Dzikir di Panti Sosial Tresna Werdha Budi Mulia 1 Cipayung – Jakarta Timur
Authors: Dewini Adelia Pratiwi , Halim M Jufri
Published: April 2022

Lanjut usia meruakan suatu keadaan yang ditandai dengan perubahan dan penurunan kesehatan, kekuatan, ketahanan fisik serta daya kemampuan untuk menjalankan kegiatan sehari-hari. Kondisi kelemahan dan penurunan tersebut menjadi masalah yang serius yang dapat mengakibatkan kecemasan. Selain mengalami penurunan fisik, para lansia harus menghadapi masalah psikologis seperti kekhawatiran tentang rasa takutnya terhadap kematian, kehilangan keluarga atau teman karib, dukungan sosial. Panti sosial ini telah memberikan bimbingan agama kepada lansia terutma kegiatan dzikir “Dzikir Ratib Al-Hadad” secara khusus diberikan oleh pihak panti berupa memberikan jalan yang dapat mengatasi lansia dari kecemasan. Penelitian ini bertujuan untuk menganalisis proses bimbingan agama dalam mengatasi kecemasan pada lansia melalui dzikir dan faktor pendukung dan penghambat bimbingan agama dala mengatasi kecemasan pada lansia melalui dzikir. Metodologi penelitian yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan pendekatan deskriptif. Teknik pengumpulan data yan digunakan adalah observasi, wawancara dan dokumentasi. Juga dari referensi buku, jurnal dan data lembaga yang terkait dengan lansia. Hasil penelitin ini menjelaskan bahwa proses pelaksanaan bimbingan agama memiliki berpengaruh terutama dalam kegiatan dzikir dalam mengatasi kecemasan pada lansia. Kegiatan dzikir khusus dengan materi Dzikir Ratib Al-Hadad. Keutaman dari dzikir ini adalah jika mengamalkannya akan dipanjangkan umur, mendapat khusnul khotimah dan senantiasa berada dalam perlindungan Allah SWT. Dzikir ini membawa perubahan pada lansia dalam mengatasi kecemasan. Adanya ketenangan dan ketentraman jiwa, kebahagiaan serta mengingatkan akan kematian dengan khusnul khotimah. Faktor pendukungnya yaitu dari sarana dan prasarana serta dukungan besar dari semua pihak panti sosial. Sedangkan faktor penghambatnya adalah kondisi penurunan fisik dan kesehatan.
Hubungan Penyuluhan Agama Dengan Pengetahuan Agama Jamaah di Majelis Ta’lim Aisyahturidho Kecamatan Cilodong - Depok
Authors: Fitriyani Anisa , Solihin Muhtar Mochamad
Published: April 2022

Pendidikan agama islam non formal seperti majelis taklim merupakan pendidikan yang memberikan pengetahuan mengenai islam agar senantiasa meningkatkan keimanan dan ketakwaannya kepada Allah SWT. sesuai dengan Al-Qur’an dan Hadits. Penyuluhan agama islam merupakan salah satu upaya yang dapat dilakukan dalam memberikan pengetahuan kepada jamaah majelis ta’lim. Tujuan penelitian ini adalah untuk mendeskripsikan pengetahuan agama jamaah majelis ta’lim, menganalisis hubungan penyuluhan agama serta untuk mengetahui faktor-faktor yang berhubungan dengan pengetahuan agama jamaah di Majelis Taklim Aisyahturidho Kecamatan Cilodong. Penelitian ini menggunakan pendekatan penelitian kuantitatif dengan metode sensus. Responden penelitian ini adalah ibu-ibu jamaah Majelis Ta’lim Aisyaturridho yang berjumlah 30 responden. Analisis data korelasi rank spearman yang diuji menggunakan SPSS 22. Hasil penelitian menunjukkan bahwa terdapat hubungan yang signifikan dan positif antara penyuluhan agama dengan pengetahuan agama jamaah Majelis Taklim Aisyahturidho dengan nilai signifikan 0,000<0,05 dan nilai koefisien korelasi sebesar 0,634 artinya tingkat keeratan korelasi yang kuat dan bernilai positif bermakna searah artinya apabila penyuluhan tinggi maka pengetahuan agama meningkat, dan apabila penyuluhan rendah maka pengetahuan agama rendah pula. Kemudian tingkat pengetahuan agama jamaah Majelis Taklim Aisyahturidho tinggi sebesar 57 persen, dan faktor-faktor yang berhubungan dengan pengetahuan agama adalah aqidah, ibadah, akhlak, metode, ceramah, serta media audio visual.
Mekanisme Problem Focused Coping Perempuan Korban Kekerasan Dalam Rumah Tangga Melalui Bimbingan Mental dan Spiritual
Authors: Naimah Nella Alfin , Prihatini Rini Laili
Published: April 2022

Data Komisi Nasional (Komnas) Perempuan (2019) menunjukan bahwa terdapat 9.637 kasus Kekerasan Dalam Rumah Tangga (KDRT) terhadap perempuan. Data tersebut belum sepenuhnya menunjukan kasus yang sebenarnya terjadi di lapangan karena masih banyak korban KDRT yang belum berani melapor. Hal tersebut memberikan makna bahwa perempuan korban KDRT perlu mendapatkan bimbingan agar mereka memiliki kemampuan Problem Focused Coping dalam menyelesaikan permasalahannya serta membantu mereka berani melihat penyebab masalah secara realistis dan berusaha mencari jalan keluar demi kehidupan masa depannya yang lebih baik. Tujuan penelitian ini adalah menganalisis: 1) metode yang dilakukan pembimbing mental spiritual dalam mendorong mekanisme problem focused coping, 2) bentuk problem focused coping yang dilakukan perempuan korban KDRT di PSP Bhakti Kasih.Teori yang digunakan dalam penelitian ini adalah teori problem focused coping serta metode bimbingan mental spiritual. Penelitian ini menggunakan jenis penelitian kualitatif dengan pendekatan fenomenologi. Hasil penelitian ini menunjukan bahwa: 1) metode yang digunakan pembimbing mental spiritual PSP Bhakti Kasih adalah metode group guidance dan metode direktif, 2) bentuk problem focused coping yang dilakukan WBS PSP Bhakti Kasih adalah active coping, seeking social support, dan planful problem solving.
Partisipasi Masyarakat pada Pemilihan Gubernur Jakarta 2017
Authors: Sukri Mhd. Alfahjri
Published: April 2022

Abstract: This study aims to see and analyze how the public's participation in the 2017 DKI Jakarta Governor Election (Pilgub), especially in Bangka Village, Mampang Prampatan District, South Jakarta TPS 30 in the first round of the DKI Jakarta Pilkada, and how the DKI Jakarta Pilkada is held at TPS 30 2017. The research method used in this research is a qualitative method by conducting field studies, observations, collecting data through using books and documents. The results of this study indicate that the participation of the community in Bangka TPS 30 RW 5 (RT 4 and 5) is high, especially the participation of the elite (high economy) who lives in RT 5. The number of people in RT 5 is present and the low number of golput (which does not use the right to vote) indicates that the participation of the elite is high. Huntington and Nelson's statement which states that a high or good economic level will result in high participation is evident at this TPS 30. However, there are some old problems in the implementation of the first round of the DKI Jakarta Pilkada in the Bangka TPS 30 Village, namely the DPT problem, such as residents whose names are not on the DPT and the DPTb which slightly resulted in residents not being able to vote. Poor implementation of Pilkada can result in decreased community participation. But overall the Pilkada at TPS 30 went smoothly and there were no problems with religious sentiment.Abstrak: Penelitian ini bertujuan untuk melihat dan menganalisa bagaimana partisipasi masyarakat pada Pemilihan Gubernur (Pilgub) DKI Jakarta tahun 2017 khususnya di Kelurahan Bangka, Kecamatan Mampang Prampatan, Jakarta Selatan TPS 30 pada Pilkada DKI Jakarta putaran pertama, dan bagaimana penyelenggaraan Pilkada DKI  Jakarta di TPS 30 tahun 2017 tersebut. Metode penelitian yang digunakan dalam penelitian ini adalah metode kualitatif dengan melakukan studi lapangan, observasi, mengumpulkan data-data melalui buku dan dokumen. Hasil dari penelitian ini menunjukkan bahwa partisipasi masyarakat Kelurahan Bangka TPS 30 RW 5 (RT 4 dan 5) termasuk tinggi, terutama partisipasi dari kalangan elite (ekonomi tinggi) yang tinggal di RT 5. Banyaknya masyarakat RT 5 yang hadir dan sedikitnya angka golput (yang tidak menggunakan hak pilih) menunjukkan bahwa partisipasi kaum elite tersebut tinggi. Pernyataan Huntington dan Nelson yang menyatakan bahwa tingkat ekonomi yang tinggi atau baik akan menghasilkan partisipasi yang tinggi, terbukti di TPS 30 ini. Namun, terdapat beberapa permasalahan lama pada penyelenggaraan Pilkada DKI Jakarta putaran pertama Kelurahan Bangka TPS 30 yaitu masalah DPT, seperti warga yang namanya tidak ada di DPT serta DPTb yang sedikit mengakibatkan warga tidak bisa memilih. Buruknya pelenggaraan Pilkada dapat berakibat pada menurunnya partisipasi masyarakat. Namun secara keseluruhan penyelenggaraan Pilkada di TPS 30 berjalan aman serta tidak ada masalah sentiment agama.
A Pharmacoeconomic Comparison of Cost Variation among Hypolipidemic Drugs Available in Indian Market
Authors: Shinde Meghna , Kushwah Anjali
Published: April 2022

Hyperlipidemia is a major cause of atherosclerotic coronary and cerebrovascular disorders affecting a large Indian population. The cost of various hypolipidemic drugs that are used for the prevention and treatment of these afflictions largely varies in the Indian pharmaceutical market. Our study aimed to evaluate the cost variation of different brands of hypolipidemic drugs and to compare the branded prices with their corresponding generic and ceiling prices. The costs of various drugs were procured from the latest issue of the “Drug Today” from October to November 2020 edition which is a directory of all the drugs available in India published quarterly every year by Lorina Publications (India) Inc. Cost ratio, percent cost variation, and daily defined dose (DDD) were calculated. We also compared the branded prices of drugs with their generic and ceiling prices available on the official website.A total of 9 single hypolipidemic drugs and 9 fixed-dose combinations (FDC) showed a wide per cent cost variation. The highest percentage of cost variation was atorvastatin 80 mg (3284%) whereas fenofibrate showed the lowest percent cost variation (0.91%). The cost ratio was also found higher in 2 from 6 drugs. Among FDCs, atorvastatin 10mg + ezetimibe 10 mg (484%) showed a higher cost variation and rosuvastatin 20 mg + fenofibrate 160mg (0.6%) showed a minimum variation. The maximum cost variation from branded prices compared to generic prices was found in simvastatin 20 mg (544%) and atorvastatin 10 mg (155%). In summary, our study showed a wide variation in the cost of hypolipidemic drugs available in the Indian market which provides an insight to the prescriber, gives drug price control authorities to minimize the financial burden on the patient, and improves their compliance
De Maldesarrollo a Decrecimiento: Una visión posfósil y globalmente justa para las sociedades del Norte global
Authors: Schmelzer Matthias
Published: April 2022

¿Por qué en el debate crítico sobre el desarrollo y el período posterior al desarrollo se suele hablar sólo de los países del Sur global? ¿Y qué significaría dirigir también la perspectiva posdesarrollo a los países del Norte global? Estas cuestiones están en el origen del debate sobre el decrecimiento desarrollado desde Francia a partir de la década de 2000. Este artículo ofrece una visión general del actual debate sobre el decrecimiento, centrándose en la crítica Sur-Norte y las propuestas de cambio de sistema. Basándose en la sistematización de las estrategias de transformación del sociólogo e investigador utópico Erik Olin Wright, este artículo analiza la medida en la que el decrecimiento es deseable, factible y alcanzable.
El proyecto de recuperación de la navegabilidad del río Magdalena y conflictos ambientales relacionados
Authors: Delvalle-Quevedo Rocío , Rojas-Robles Rosario
Published: April 2022

Este artículo tiene como objeto documentar el Proyecto de Recuperación de la Navegabilidad del río Magdalena en su llanura inundable, destacando posibles afectaciones ecosistémicas y sociales, estrategias de territorialización y conflictos ambientales generados. De la dinámica de inundación-sequía del río Magdalena dependen el ciclo productivo de sus llanuras aluviales, la fisiología, comportamiento y reproducción de los peces, la cultura de la pesca artesanal y los medios de vida de las comunidades que allí habitan. A este complejo territorio llega el Proyecto de Navegabilidad, con una estrategia de mejoramiento del desempeño logístico basado en la multimodalidad del transporte, las Asociaciones Público-Privadas (APP) y el aprovechamiento de las ventajas del transporte fluvial. Todo esto, con el objetivo de optimizar el transporte de hidrocarburos y minerales previamente extraídos para el comercio exterior. Estas obras generarían serias afectaciones a la diversidad y complejidad del río, como resultado del intento de fijar y estabilizar un ambiente que es dinámico y cambiante, lo cual refleja el desconocimiento del río y la falta de visión de cuenca. Todo ello puede afectar a las comunidades ribereñas, en especial los pescadores artesanales que han construido sus territorios en torno al río y sus planicies de inundación. Ellos presentan resistencia al proyecto por considerarlo una amenaza a su territorialidad, lo que genera nuevos conflictos ambientales.
Un enfoque desde la sustentabilidad: análisis de ciclo de vida como herramienta para la toma de decisiones en el desarrollo de proyectos hidroeléctricos en Colombia
Authors: Martínez-Vallejo Leonel Alexander , Cortés-Mora Hernán G. , Méndez-Alcázar Johann Andrés , Peña-Reyes José Ismael
Published: April 2022

La capacidad instalada para generación de energía hidroeléctrica constituye el 69,2% de la matriz energética de Colombia, lo cual se debe a las características geográficas y a los recursos hídricos de este país. Aunque esta forma de generación es considerada renovable, las hidroeléctricas implican la construcción de presas y depósitos de agua (áreas inundadas) que, además de impactos ambientales en las comunidades, el suelo, el agua y el entorno en general, generan gases de efecto invernadero. Nuevas centrales hidroeléctricas se construirán en el país, por lo que se sugiere evaluarlas bajo una perspectiva de la sustentabilidad, entendida como la articulación de variables sociales, económicas, ambientales y culturales en búsqueda de un equilibrio a lo largo del tiempo. Se propone para esto el Análisis de Ciclo de Vida (ACV) como una herramienta para determinar impactos ambientales de proyectos hidroeléctricos. Este trabajo revisa cómo el enfoque de sustentabilidad puede apoyarse en herramientas ampliamente utilizadas en los proyectos de ingeniería como el ACV y el Análisis de Ciclo de Vida Social (ACVs) para conocer el impacto de proyectos hidroeléctricos en todas sus fases, abordando las dimensiones ambientales y sociales. La dimensión económica no se tuvo en cuenta, abriendo el camino para nuevos aportes. Se concluye que existe la necesidad de iniciar la construcción de una línea base de información para aplicar herramientas como el ACV y el ACVs, orientada a la sustentabilidad para proyectos de hidroeléctricas, tanto para los que se encuentren en planeación, como los que operan actualmente. Se sugieren aspectos para tener en cuenta en la toma de decisiones con el fin de contribuir a la sustentabilidad para futuros proyectos.
Análisis de la vulnerabilidad de la hidroelectricidad en Colombia
Authors: Bacca-García Javier Orlando , Toro Javier
Published: April 2022

Las hidroeléctricas se han convertido en la principal forma de generación de energía eléctrica en el país, en especial las centrales de embalse, las cuales han sido implementadas teniendo en cuenta las condiciones topográficas e hídricas del territorio nacional, junto con las dinámicas económicas y políticas que promueven el desarrollo de este tipo de infraestructura. Sin embargo, en el país se han presentado condiciones climáticas (ciclo ENOS/Oscilación Sur) que han afectado de manera significativa los niveles de almacenamiento de las represas; adicionalmente la construcción y funcionamiento de este tipo de infraestructuras genera múltiples impactos ambientales en las comunidades cercanas y sus territorios, produciendo inquietudes sobre la pertinencia de depender en un alto porcentaje de este modelo de generación. De acuerdo con lo anterior, se hace un análisis del modelo actual desde un enfoque ambiental, teniendo en cuenta las dinámicas y contextos en las que se instauran este tipo de proyectos. Con este objetivo se analizan los impactos ambientales relacionados con la ejecución y el funcionamiento de las represas, así como la vulnerabilidad en la prestación del servicio en relación con la variabilidad climática y los fenómenos meteorológicos que inciden en el territorio nacional. Lo anterior se hace mediante una revisión exhaustiva de literatura y con la propuesta de un análisis de vulnerabilidad, basado en el volumen útil diario de los embalses que aportan al Sistema Interconectado Nacional (SIN). De este modo se determina la alta dependencia que se tiene en una sola tecnología, haciendo necesario replantearse la complementariedad del sistema mediante la implementación y fortalecimiento de otras fuentes alternativas de energías renovables que generen una canasta energética más diversa y estable.
Marco contextual: la normatividad ambiental como escudera de las grandes represas
Authors: Montoya-Domínguez Estefanía , Santander-Durán Jenny-Paola
Published: April 2022

En la concepción de los marcos normativos ambientales nacionales se vinculan lecturas situadas, bien sea local o internacionalmente, de apuestas de crecimiento económico, progreso y percepciones del daño ambiental. A partir de esto se consolidan los procesos de otorgamiento de permisos y de seguimiento de proyectos, obras o actividades, entre los cuales se encuentran las grandes hidroeléctricas. En este sentido, esta comunicación breve aborda dos periodos del desarrollo normativo colombiano que sirvieron como base para consolidar una visión utilitarista de la naturaleza que no ha sido superada, poniendo en grave riesgo la sostenibilidad y resiliencia de diversos territorios y comunidades en Colombia.
Flujo de intereses y represamiento territorial: debates en torno al proyecto hidroeléctrico Hidroituango
Authors: Montoya-Domínguez Estefanía , Santander-Durán Jenny-Paola
Published: April 2022

La construcción de grandes represas ha sido la elección de los gobiernos de Colombia para abastecer de energía eléctrica a la población colombiana, siguiendo el modelo estadounidense de la década de 1950, el cual se consolida más de 40 años después para mantener sus compromisos de energía en firme. Allí se origina el proyecto Hidroituango, una sucesión de errores e intereses concatenados que ha construido una crisis ambiental sin precedentes en Colombia y mantiene a las comunidades del norte antioqueño y bajo Cauca en un estado permanente de riesgo e incertidumbre, sumando un factor más a la grave situación de derechos humanos que se vive desde la década de 1980 por el conflicto armado. Por consiguiente, este artículo aborda el conflicto ambiental derivado de su puesta en marcha, desde un enfoque que cuestiona el poder técnico y político que le ha rodeado desde su formulación, la omisión de la complejidad ambiental del territorio cañonero y la consecuente amenaza de su identidad ecológica y cultural. Se concluye sobre la necesidad de avanzar en la construcción de instancias interinstitucionales y multiactor de evaluación y seguimiento, a partir de las cuales se empiece a superar la crisis ambiental que expresan estos proyectos e incluyan un eje central de construcción de paz, en la medida que estas obras no se emplazan en lugares vacíos, sin memoria o historia local, siendo mucho más que zonas de sacrificio para el Desarrollo.
Sustituto de fungicidas químicos sintéticos con aceite esencial de orégano para el control del Fusarium oxysporum
Authors: Silva-Marrufo Oscar , Marín-Tinoco Rubén Iván
Published: April 2022

El chile ancho (variedad cardenal y sargento) es uno de los principales cultivos de la región de Rodeo, Durango, México, gracias a su significado culinario, su utilidad agroindustrial e Importancia como producto nacional comercializable. Lamentablemente sufre grandes daños causados por hongos; a mayor escala se presenta el Fusarium oxysporum, que origina marchitez en el chile y, en consecuencia, pérdidas económicas considerables. Este escrito evalúa el efecto de la aplicación vía foliar del aceite esencial de orégano en las plantas, con el fin de controlar el índice de daño causado por este hongo presente en el suelo. El artículo se desarrolla a través de la recolección de muestras de suelo, para identificar el hongo mediante la técnica de flotación; así, es posible lograr esta identificación mediante microscopio 4X, controlando orgánicamente la toxina con el aceite esencial de orégano de la variedad Lippia graveolens. Para esto se toman cuatro concentraciones de 1,5; 1,0; 0,5 y 0 mL este último como testigo, y se aplican tres réplicas para cada una, en cuatro variables por evaluar: (a) altura de planta; (b) peso de hojas; (c) peso de raíz, (d) diámetro del tallo, y (e) número de ramas. Los resultados arrojan que las concentraciones de 0,5 y 1,5 mL de aceite esencial cuentan con mejores condiciones de peso de la planta y mayor frondosidad. De este modo, el testigo se estabiliza, y en la concentración 1,0 se observan pérdidas de baja escala.
Pirólisis rápida para producir biocombustibles con residuos sólidos urbanos: estudio de caso, Madrid, Cundinamarca
Authors: Acosta-Rubio Daniela , Castro-Camacho Lizbeth , Moreno-Arias Claudio Alberto
Published: April 2022

El presente artículo propone analizar el aprovechamiento energético de los residuos sólidos urbanos y establece como caso de estudio el municipio de Madrid, Cundinamarca. Los resultados presentados se obtuvieron del proyecto Diseño del proceso de pirólisis para la producción de biocombustibles a partir de residuos sólidos urbanos (RSU), desarrollado por los autores. Para dicho análisis, se tiene en cuenta la disponibilidad de residuos en el municipio, se establecen los diferentes parámetros de operación, y se determinan las etapas del proceso. Posteriormente se desarrollan tanto el balance de materia como el de energía y se sintetiza la información en el diagrama PFD. Finalmente se consideran las metas planteadas en el Protocolo de Kioto (Ministerio de Ambiente y Desarrollo Sostenible [MADS], s.f. b) y lo establecido por el Departamento Nacional de Planeación Colombia (2016), en su Documento Conpes 3874, definiendo así el proyecto como una economía circular. Con esta información se obtiene una producción anual de aproximadamente 967,3 toneladas de biochar, 4183,5 toneladas de bioaceite y 1287,7 toneladas de biogás, únicamente para el aprovechamiento de los residuos sólidos orgánicos producidos en el municipio de Madrid. Sin embargo, se requieren elevados costos de inversión, además de profundización en las investigaciones sobre el diseño de la planta y sus parámetros de operación. Esta información puede utilizarse como base para el diseño de futuros procesos de pirólisis. Además, es necesario destacar que la producción de dichos biocombustibles con residuos sólidos brindaría al país impactos positivos económicos, ambientales y sociales.
New Perspectives for Living Traditions: Intangible Cultural Heritage in North-East Hungary
Authors: Tóth Arnold
Published: April 2022

The UNESCO World Heritage Convention (1972) was originally focused on nature conservation and built heritage. The immaterial aspect of the worldwide heritage discourse arrived at a turning point in 2003, when the Convention for the Safeguarding of Intangible Cultural Heritage was adopted. The definition of the intangible cultural heritage provides essential frames for a wide range of interpretations. The UNESCO concept focuses on inclusive, representative and community-based traditions which are contemporary and living at the same time. In this sense, the intangible cultural heritage conception is based on the fundamental dichotomy of tradition and modernity. For the communities concerned, a new perspective for living traditions is the process from tradition to heritage. There are four essential features of this process: participation, consciousness, organization and valorization. They can make a difference between tradition and heritage. The Hungarian model for the implementation of the UNESCO Convention is based on a bottom-up system, where the heritage bearers themselves initiate the nomination process for the National Inventory. It is based on their strong commitment to their heritage and it relies on their involvement and participation. In this paper, three case studies from North-East Hungary (Borsod-Abaúj-Zemplén County) represent different ways of “creating a heritage.” The various patterns are closely related to the ideas of identity, community cohesion, tourism, local economy and the preservation of living traditions.
Visualization of the effect of TR100 anti-cancer compound on membrane nanotubes with SR-SIM microscopy
Authors: Hencz Alexandra Júlia , Somogyi Pál , Halász Henriett , Szabó-Meleg Edina
Published: April 2022

One of the most dangerous diseases is cancer, nearly 2 million new cancer types are diagnosed each year, worldwide, causing most of the death. Therefore, cancer is in the focus of many types of research. To prevent the proliferation and spreading of malignant cells, several compounds have been developed in chemotherapy, however, a significant proportion of these have serious side effects, and resistance is commonly emerging early after administration. Tumor cells require tropomyosin-containing actin network for their growth and survival. The tropomyosin profile is considerably changed in cancers resulting in the dramatic rearrangements of the actin cytoskeleton structure, therefore anti-tropomyosin compounds can be a new perspective in cancer therapy, such as TR100 which was reported to be capable of destroying cancer cells in a highly tumor-specific manner by increasing the depolymerization of the actin filament. On the other hand tumor cells can commonly communicate with each other via membrane nanotubes (NTs) for which actin is essential for growth. Tumor cell NTs may transport not only signal molecules, or cell organelles, but resistance factors against chemotherapeutic agents to help to survive. Immune cells also frequently use membrane nanotubes for communication, therefore, in this study we focused on the visualization of the effect of TR100 on the morphology and formation of B lymphoma cell NTs with superresolution structured illumination microscopy. TR100 treatment caused spectacular changes on the NT forming capability and the morphology of B cells in a concentration dependent manner, while low concentration of the agent significantly promoted NT formation, and at the same time produced shorter and thicker tubes in the early stage of their formation, in higher concentration it affected mainly only the cells, causing the rounding and finally the death of them. We were not able to detect any significant change on cells with extended nanotubular network, suggesting that TR100 is a less potent candidate in anti-cancer therapy.
Effect of high fat diet on structure of liver and gallbladder of adult male mice – an experimental study
Authors:   Human Anatomy & Embryology Department, Faculty of Medicine, Zagazig University, Zagazig City, Egypt, Hegazy Abdelmonem Awad ,   Medical Biotechnology Department, College of Biotechnology, Misr University for Science and Technology (MUST), 6th of October City, Egypt, Qenawy Noura M. ,   Human Anatomy & Embryology Department, Faculty of Medicine, Zagazig University, Zagazig City, Egypt, Aziz Nada M. Abdel ,   Human Anatomy & Embryology Department, Faculty of Medicine, Zagazig University, Zagazig City, Egypt, El-Bestawy Emtethal M. ,   Human Anatomy & Embryology Department, Faculty of Medicine, Zagazig University, Zagazig City, Egypt
Published: April 2022

Introduction. High fat diet (HFD) intake induces obesity and adversely affects different body organs including liver and gallbladder. Aim. It was to clarify the effects of HFD on the liver and gallbladder structure using light microscopic (LM) examination. Material and methods. 16 healthy adult male mice were equally divided into 2 groups. Control group mice were fed normal diet. HFD group was fed using HFD. At the end of the 8-week experiment, mice were anesthetized. Liver and gallbladder were removed and prepared to histological processing. Sections were stained with hematoxylin and eosin (H&E) and immunostaining for cyclooxygenase-2 (COX-2) cellular localization. Oil Red O (ORO)-stained frozen liver sections were prepared. Results. H&E-stained sections of HFD group revealed rounded swollen hepatic cells with pale cytoplasm suggesting cellular ballooning. Dilated congested sinusoids and portal vein, cellular degeneration and collection of inflammatory cells were observed between hepatic cells and in portal region. Gallbladder sections showed epithelial stratification and cellular vacuolation. Strong immunoexpression of COX-2 was observed in Kupffer and hepatic cells of the liver and gallbladder mucosal epithelial cells. Conclusion. HFD is suggested to alter the normal histological features of liver and gallbladder represented by fatty liver and gallbladder epithelial hyperplasia and inflammatory reaction.
A Mobilização do relatório Brasil: Nunca Mais nas sugestões encaminhadas pela população à Assembleia Nacional Constituinte
Authors: BAUER Caroline Silveira
Published: April 2022

Resumo Este artigo propõe uma reflexão sobre as recepções e apropriações do relatório Brasil: Nunca Mais a partir das sugestões apresentadas por seus leitores à Assembleia Nacional Constituinte. O objetivo é explicitar a importância do relatório na formulação e na transmissão de uma perspectiva sobre o passado que confrontava a política de esquecimento imposta pela ditadura civil-militar. Utiliza-se o fundo documental do Projeto Diga Gente, que deu origem ao Sistema de Apoio Informático à Constituinte (SAIC), disponível no sítio do Senado Federal. Argumenta-se que essas pessoas, ao mobilizarem sua leitura do Brasil: Nunca Mais, evidenciam certas representações sobre o passado ditatorial articuladas a determinadas expectativas de futuro e apresentam motivações específicas para a transmissão da experiência do terrorismo de Estado em uma conjuntura de transformações institucionais e políticas. Dessa forma, é possível compreender, parcialmente, a difusão, a circulação, a recepção e os usos do Brasil: Nunca mais e sua importância na conformação de uma memória da ditadura durante a transição política.
Efeitos da fotobiomodulação associada a terapia miofuncional orofacial na qualidade de vida de indivíduos com disfunção temporomandibular
Authors: Dias Wellyda Cinthya Félix Gomes da Silva , Cavalcanti Renata Veiga Andersen , Magalhães Júnior Hipólito Virgílio , Pernambuco Leandro de Araújo , Alves Giorvan Ânderson dos Santos
Published: April 2022

RESUMO Objetivo Analisar o impacto na qualidade de vida relacionada à saúde oral de indivíduos com disfunção temporomandibular, antes e após o tratamento de fotobiomodulação associada a terapia miofuncional orofacial. Método Estudo do tipo ensaio clínico randomizado, controlado e cego, com 34 voluntários distribuídos aleatoriamente em dois grupos: G1, que recebeu a Terapia Miofuncional Orofacial (TMO) associada a fotobiomodulação e o G2, tratado pela TMO associada ao laser inativo. Os indivíduos foram submetidos, primeiramente, à avaliação para serem classificados de acordo com o grau da dor orofacial pela Escala Visual Analógica (EVA) e também quanto ao impacto da qualidade de vida relacionada a saúde oral (QVRSO) pelo questionário Oral Health Impact Profile – Short form (OHIP-14). Os dados obtidos foram analisados estatisticamente. Foi adotado o nível de significância de 0,05 (95%). Resultados “Dor física”, “desconforto psicológico”, “limitação física” e “limitação psicológica” foram os aspectos mais impactantes na QVRSO. O G1 apresentou respostas positivas para o respectivo tratamento, assim como o G2. Observou-se correlação positiva e de grau forte para EVA e escore total do OHIP-14 em ambos os grupos após tratamento. Porém, os indivíduos do grupo controle (G2) evidenciaram que a recuperação funcional foi o aspecto que mais se percebeu de mudança positiva na QVRSO em comparação ao grupo experimental (G1). Conclusão As pessoas que receberam fotobiomodulação associada a TMO-perceberam melhora da QVRSO, assim como as tratadas com o laser placebo. Houve correlação positiva e forte em ambos os grupos na melhora do grau da dor e autopercepção da QVRSO.
Substance use and meaning: transforming occupational participation and experience
Authors: Kiepek Niki , Ausman Christine , Beagan Brenda , Patten San
Published: April 2022

Abstract Introduction We draw on activity theory of concepts to examine ‘meaning of occupation’ and ‘substance use’ beyond preconceived notions of inherent positive or negative experiences. Objective To explore nuanced meanings of substance use and associated occupations. Method An online survey and semi-structured interviews were used to collect data from professionals about prevalence of substance use, substance effects, and personal experiences. In analyzing the interview data, we attended to substance use as a discrete occupation in itself, substance use co-occurring with other occupations, and substance use altering the performance, participation, and experience of occupations. Results Three broad themes related to meaning: i) complex meanings attributed to substance use, ii) meanings of substance use as shifting and variable, and iii) meanings of substance use in the context of other occupations. Substance use enhances occupations, transforms meaning of occupations, and mitigates less desired aspects of occupations. Work, construed as positively meaningful and valued in occupational therapy literature, was a source of stress, unhappiness, and worry; substance use facilitated relaxation and pleasure. Conclusion This study furthers occupational therapy knowledge with respect to implications for conceptualization that extend beyond dualist framings and implications for occupational therapy education, practice, and policy.
Immunophenotypical and pathological changes in dogs experimentally infected with Ehrlichia canis
Authors: Castro Márcio Botelho de , Szabó Matias Pablo Juan , Aquino Lucia Padilha Cury Thomaz de , Dagnoni Ana Silvia , Alessi Antonio Carlos , Costa Mirela Tinucci , Nakaghi Andréa Cristina Higa , Santi Mariele De , Calchi Ana Claúdia , André Marcos Rogério , Machado Rosangela Zacarias
Published: April 2022

Abstract Canine monocytic ehrlichiosis (CME) is one of the most important tick-borne diseases worldwide, with multisystemic presentations. Immune dysregulation has been proposed as the primary mechanism involved in its pathogenesis and in tissue injury in dogs with CME. Experimental infection of German Shepherd dogs in the present study demonstrated that CME caused marked pathological changes in their lymph nodes and spleen, and also gave rise to mononuclear infiltration in organs and tissues. Immunophenotyping of cells in lymph nodes, spleen and injured tissues highlighted differences in lymphocyte subsets, local expression of immunoglobulin subclasses and MHCII molecules between infected and control dogs. These findings suggest that the immunophenotypic and immunopathological changes in dogs with acute experimental CME are related to Th1 bias and compartmentalized immune response.
Influence of anesthesia type on post-reperfusion syndrome during liver transplantation: a single-center retrospective study
Authors: Cho Hye-Yeon , Lee Ho-Jin , Kim Won Ho , Lee Hyung-Chul , Jung Chul-Woo , Hong Suk Kyun , Yang Seong-Mi
Published: April 2022

Background: Post-reperfusion syndrome (PRS) results in sudden hemodynamic instability following graft reperfusion. Although PRS is known to influence outcomes following liver transplantation, little is known regarding the effects of anesthetics on PRS. This study investigated the association between the type of anesthetic agent and PRS in liver transplantation. Methods: This single-center retrospective cohort study included patients who underwent liver transplantation between June 2016 and December 2019. Patients were divided into sevoflurane and propofol groups according to the anesthetic agent used. Stabilized inverse probability of treatment weighting (IPTW) analysis was performed to investigate the association between PRS identified based on blood pressure recordings and the type of anesthesia. Associations between the anesthetic agent and the duration of hypotension as well as early postoperative outcomes were also investigated.Results: Data were analyzed for 398 patients, 304 (76.4%) and 94 (23.6%) of whom were anesthetized with propofol and sevoflurane, respectively. PRS developed in 40.7% of the 398 patients. Following stabilized IPTW analysis, the association with PRS was lower in the sevoflurane group than in the propofol group (odds ratio, 0.47; P = 0.018). However, there was no association between the type of anesthetic used and early postoperative outcomes. Conclusions: The association of PRS was lower in the sevoflurane group than in the propofol group. However, there was no association between the type of anesthetic and the early postoperative outcomes. Further studies are required to determine the optimal anesthetic for liver transplantation.
Authenticity of urban tourism: A tactical urbanism perspective
Authors:   The Tourism Sciences Society Of Korea, Kim Hyun-Jung
Published: April 2022

Recently, tourism to visit areas where one can experience the daily life and sense of place of the city is preferred. This study applied a concept of tactical urbanism in terms of the authenticity of urban tourism to provide a theoretical background for revitalizing regional-led urban tourism. This study analyzed the significance and usefulness of tactical urbanism from the perspective of authenticity by applying a documentary method. As a result, the authenticity of the areas of naturalness, originality, specialness, relevance, and influence was revealed in terms of the concept, application process, and output of tactical urbanism applied to the city. A total of 10 characteristics allow tourists to feel authenticity in urban spaces to which tactical urbanism is applied. Tactical urbanism is a useful approach that gives authenticity to urban spaces, suggesting that it provides an authentic experience for both locals and tourists. This study contributed to the theoretical expansion of tourism by incorporating the tactical urbanism mainly dealt with in the field of urban planning into the concept of authenticity of urban tourism. In the future, it is suggested that tourism policies that can apply a tactical urbanism approach should be prepared to revitalize small but authentic urban tourism.
The impact of personal travel media content characteristics on a viewer’s social presence and behavioral intention
Authors:   The Tourism Sciences Society Of Korea, Lee Jun-Ho , Yoon Ji-Hwan
Published: April 2022

Personal travel media content has become an important form of marketing tool for the travel industry given its characteristics of facilitating interaction between the content creators and the viewers. Therefore, it is essential to understand the viewer’s psychological decision-making process in order to utilize it as a marketing tool in an effective way. This study was conducted using the S-0-R model. An online survey was conducted on 282 viewers who watched personal travel media within the last 6 months in which the creator is shown directly in the content. As a result of the analysis, a total of four characteristics of personal travel media contents were derived as in the theoretical study: parasocial interaction, information quality, creator’s attractiveness, and real time broadcast. All content characteristics showed a positive impact on social presence. In particular, real time broadcast had the most significant impact on viewers’ social presence. Social presence was found to have a positive impact on a viewer’s behavioral intention too. Based on the results, providing useful and genuine information through attractive creators who can communicate in real time in an effective way is needed to get positive responses from the viewers. This study is meaningful in that it identified personal travel media contents through understanding the psychological decision making process of viewers. It also provided an effective way of utilizing personal travel media content as a new marketing tool.