bluuebunny/crossref_metadata_2025 huggingface dataset:
The Boron‐Mediated Ketone—Ketone Aldol Reaction.
Authors: Cergol Katie M. , Turner Peter , Coster Mark J.
Published: May 2005

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Preparation of Complex Bridged Bicyclic Ring Systems from 3,3‐Diacetoxy‐2‐phenylsulfonylpropene and β‐Keto Esters.
Authors: Kraus George A. , Jeon Insik
Published: May 2005

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A Regioselective Synthesis of 2,4‐Dialkyl Resorcinols.
Authors: Ceglia Scott S. , Kress Michael H. , Nelson Todd D. , McNamara James M.
Published: May 2005

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2,3‐Dimethoxy‐5‐methyl‐1,4‐benzoquinones and 2‐Methyl‐1,4‐naphthoquinones: Glycation Inhibitors with Lipid Peroxidation Activity.
Authors: Jung Young‐Sik , Joe Bo‐Young , Cho Sung Ju , Konishi Yasuo
Published: May 2005

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A Short Synthesis of Trimebutine, 2‐Dimethylamino‐2‐phenylbutyl 3,4,5‐Trimethylbenzoate.
Authors: Kim Jin Yeon , An Gwang‐il , Chun Kwon‐Soo , Rhee Hakjune
Published: May 2005

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Palladium‐Catalyzed Arylation of Sulfonamide‐Stabilized Enolates.
Authors: Zeevaart Jacob G. , Parkinson Christopher J. , de Koning Charles B.
Published: May 2005

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Rhodium‐Catalyzed Synthesis of Isothiocyanate from Isonitrile and Sulfur.
Authors: Arisawa Mieko , Ashikawa Masanori , Suwa Atsushi , Yamaguchi Masahiko
Published: May 2005

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Catalytic Suzuki Coupling Reactions by Amido Phosphine Complexes of Palladium.
Authors: Liang Lan‐Chang , Chien Pin‐Shu , Huang Mei‐Hui
Published: May 2005

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Palladium‐Catalyzed Homocoupling of Aryl Halides in the Presence of Fluoride.
Authors: Seganish W. Michael , Mowery Molly E. , Riggleman Shaundra , DeShong Philip
Published: May 2005

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Synthesis of a Novel Plant Growth Promoter from Gallic Acid.
Authors: Negi Arvind Singh , Darokar Mahinder P. , Chattopadhyay Sunil K. , Garg Ankur , Bhattacharya Asish K. , Srivastava Vandana , Khanuja Suman P. S.
Published: May 2005

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Asymmetric Synthesis of Aziridines and Arylalanine Derivatives.
Authors: Lee Seung‐Han , Song In‐Woong
Published: May 2005

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Cyclohydrocarbonylation of Substituted Alkynes and Tandem Cyclohydrocarbonylation—CO Insertion of α‐Keto Alkynes Catalyzed by Immobilized Co—Rh Heterobimetallic Nanoparticles.
Authors: Park Kang Hyun , Kim So Yeon , Chung Young Keun
Published: May 2005

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2,3‐Diarylthiophenes as Selective EP1 Receptor Antagonists.
Authors: Ducharme Yves , et al. et al.
Published: May 2005

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Studies on 2‐Aminothiophenes: Synthesis, Transformations, and Biological Evaluation of Functionally‐Substituted Thiophenes and Their Fused Derivatives.
Authors: Wardakhan Wagnat W. , Gaber Hatem M. , Ouf Salama A. , Sherif Sherif M.
Published: May 2005

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Pyrrolidinedione Derivatives as Antibacterial Agents with a Novel Mode of Action.
Authors: Pohlmann Jens , Lampe Thomas , Shimada Mitsuyuki , Nell Peter G. , Pernerstorfer Josef , Svenstrup Niels , Brunner Nina A. , Schiffer Guido , Freiberg Christoph
Published: May 2005

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Synthesis of Dimethyl 1‐Aryl‐4‐ethoxy‐5‐oxo‐2,5‐dihydro‐1H‐pyrrole‐2,3‐dicarboxylates Mediated by Triphenylphosphine.
Authors: Yavari Issa , Nasiri Farough , Djahaniani Hoorieh
Published: May 2005

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Synthesis of Dialkyl 4‐Ethoxy‐2,5‐dihydro‐1‐ (9,10‐dihydro‐9,10‐dioxoanthracen‐1‐yl) ‐5‐oxo‐1H‐pyrrole‐2,3‐dicarboxylates.
Authors: Yavari Issa , Alborzi Ali R. , Dehghan Shoaleh , Nourmohammadian Farahnaz
Published: May 2005

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Phenyl‐Substituted Porphyrins. Part 1. Synthesis of meso‐Phenyl‐Substituted Porphyrins.
Authors: Syrbu S. A. , Lyubimova T. V. , Semeikin A. S.
Published: May 2005

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Preparation of Bisindolylalkanes from N‐tert‐Butanesulfinyl Aldimines.
Authors: Ke Bowen , Qin Yong , He Qinfei , Huang Zhiyan , Wang Fengpeng
Published: May 2005

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Easy Access to Aryl‐ and Heteroaryl‐Annulated[a]carbazoles by the Indium‐Catalyzed Reaction of 2‐Arylindoles with Propargyl Ethers.
Authors: Tsuchimoto Teruhisa , Matsubayashi Hiromichi , Kaneko Masayoshi , Shirakawa Eiji , Kawakami Yusuke
Published: May 2005

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Copper(II)‐Catalyzed Formation of 1,3‐Dioxolanes from Oxiranes.
Authors: Lee Seung‐Han , Lee Jae‐Chul , Li Ming‐Xing , Kim Nam‐Sun
Published: May 2005

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Phase‐Transfer Catalyzed Alkylation and Cycloalkylation of 3‐Substituted‐1H‐pyrazol‐2‐in‐5‐ones in the Absence or Presence of Carbon Disulfide.
Authors: Khalil A. Kh. , Hassan M. A. , Mohamed M. M. , El‐Sayed A. M.
Published: May 2005

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Synthesis and Antimycobacterial Activity of 2‐Substituted Halogenobenzimidazoles.
Authors: Kazimierczuk Z. , Andrzejewska M. , Kaustova J. , Klimesova V.
Published: May 2005

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De novo Design, Synthesis, and in vitro Activity of LFA‐1 Antagonists Based on a Bicyclic[5.5]hydantoin Scaffold.
Authors: Dhar T. G. Murali , et al. et al.
Published: May 2005

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Reactions of Cyanothioformamide and Thiohydantoin Derivatives with Some Arylidenes of Cyanothioacetamide and Other Electrophilic and Nucleophilic Reagents.
Authors: El‐Sharief A. M. Sh. , Mahmoud F. F. , Taha N. M. , Ahmed E. M.
Published: May 2005

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Synthesis and Structure—Activity Relationships of Isoxazole Carboxamides as Growth Hormone Secretagogue Receptor Antagonists.
Authors: Xin Zhili , Zhao Hongyu , Serby Michael D. , Liu Bo , Schaefer Verlyn G. , Falls Douglas H. , Kaszubska Wiweka , Colins Christine A. , Sham Hing L. , Liu Gang
Published: May 2005

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Synthesis, Stereochemistry and Biological Activity of Some Novel Long Alkyl Chain Substituted Thiazolidin‐4‐ones and Thiazan‐4‐one from 10‐Undecenoic Acid Hydrazide.
Authors: Rahman V. P. Mujeebur , Mukhtar Sayeed , Ansari Wajid Husain , Lemiere Guy
Published: May 2005

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Regioselective Synthesis of 6‐Benzylthiazolo[3,2‐b]1,2,4‐triazoles During Sonogashira Coupling.
Authors: Heravi Majid M. , Kivanloo Ali , Rahimzadeh Mohammad , Bakavoli Mehdi , Ghassemzadeh Mitra , Neumueller Bernhard
Published: May 2005

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Synthesis and Biological Activities of Novel 1,4‐Bridged Bis‐1,2,4‐triazoles, Bis‐1,3,4‐thiadiazoles and Bis‐1,3,4‐oxadiazoles.
Authors: Shaker R. M. , Mahmoud A. F. , Abdel‐Latif F. F.
Published: May 2005

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A Stereocontrolled Route to Protected Isocyanates from Alcohols.
Authors: Cane‐Honeysett Daniel J. , Dowle Michael D. , Wood Mark E.
Published: May 2005

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The Furan Approach to Oxacycles. Part 3. Stereoselective Synthesis of 2,3‐Disubstituted Tetrahydropyrans.
Authors: Alonso David , Perez Manuel , Gomez Generosa , Covelo Berta , Fall Yagamare
Published: May 2005

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Synthesis of 3‐Benzyl‐2‐hydroxy‐7,8‐dihydro‐6H‐quinolin‐5‐ones from Baylis—Hillman Adducts.
Authors: Gowrisankar Saravanan , Na Jeong Eun , Lee Mi Jung , Kim Jae Nyoung
Published: May 2005

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Modified Friedlaender Synthesis of Quinolines from N‐Phenyl Cyclic Enaminones.
Authors: Na Jeong Eun , Lee Ka Young , Park Da Youn , Kim Jae Nyoung
Published: May 2005

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A Mild and Efficient One‐Step Synthesis of Quinolines.
Authors: De Surya K. , Gibbs Richard A.
Published: May 2005

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1,8‐Naphthyridines. Part 5. Novel N‐Substituted 5‐Amino‐N,N‐diethyl‐9‐isopropyl[1,2,4]triazolo[4,3‐a] [1,8]naphthyridine‐6‐carboxamides, as Potent Antiinflammatory and/or Analgesic Agents Completely Devoid of Acute Gastrolesivity.
Authors: Grossi Giancarlo , Di Braccio Mario , Roma Giorgio , Ballabeni Vigilio , Tognolini Massimiliano , Barocelli Elisabetta
Published: May 2005

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First Hetero‐Diels—Alder Reaction with Indoloquinone in the Presence of Hydrogen and Palladium.
Authors: Gentili Jacques , Barret Roland
Published: May 2005

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Synthesis of 2‐Amino‐3‐hydroxy‐4‐substituted Pyridines via Regioselective Metalation of 3‐(1‐Ethylpropyl)[1,3]oxazolo[4,5‐b]pyridin‐2(3H)‐one and Application to Corticotropin Releasing Factor1 Receptor Ligands.
Authors: Hartz Richard A. , Nanda Kausik K. , Ingalls Charles L.
Published: May 2005

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Stereoselective Synthesis of 2,5‐Disubstituted‐1,4‐oxathiane S‐Oxides.
Authors: Bedford Simon T. , Grainger Richard S. , Steed Jonathan W. , Tisselli Patrizia
Published: May 2005

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Novel Synthesis of Thieno[2,3‐c]pyridazine and Pyrimido[4′,5′:4,5]thieno[2,3‐c]pyridazine Derivatives
Authors: El‐Dean A. M. Kamal , El‐Gaby M. S. A. , Gaber A. M. , Eyada H. A. , Al‐Kamali A. S N.
Published: May 2005

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Transformations of 1,2,4‐Triazine 4‐Oxides to Pyridazines and Triazolo[4,3‐b]pyridazines by the Action of Substituted Acetonitriles.
Authors: Kozhevnikov Dmitry N. , Kataeva Natalia N. , Rusinov Vladimir L. , Chupakhin Oleg N. , Aleksandrov Grigory G.
Published: May 2005

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Microwave‐Assisted Synthesis of Novel Imidazo‐ and Pyrimidopyrido[4′,3′:4,5]thieno[2,3‐d]pyrimidines.
Authors: Ahmed Essam Kh. , Ameem Mohamed A. , Abdel‐Latif Fathy F.
Published: May 2005

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Synthesis of Some Bicyclic Thiazolo‐ and Oxothiazolo‐Pyrimidines.
Authors: Mobinikhaledi A. , Foroughifar N. , Ahmadi B.
Published: May 2005

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Synthesis and Reactions of Some New Heterocyclic Compounds Related to Pyrrolylthieno[2,3‐d]pyrimidines and Thieno[2,3‐d][4,5‐d]dipyrimidines.
Authors: Moneam Maisa I. Abdel
Published: May 2005

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Recyclization of 2‐Iminocoumarins Using Nucleophilic Reagents. Part 6. Reaction of 2‐Iminocoumarin‐3‐carboxamides with 2‐Aminobenzophenones.
Authors: Rusanova S. V. , Zhuravel I. A. , Kovalenko S. N. , Chernykh V. P. , Baumer V. N.
Published: May 2005

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Structure‐Based Design of Potent and Selective Inhibitors of Collagenase‐3 (MMP‐13).
Authors: Kim Soong‐Hoon , Pudzianowski Andrew T. , Leavitt Kenneth J. , Barbosa Joseph , McDonnell Patricia A. , Metzler William J. , Rankin Bruce M. , Liu Richard , Vaccaro Wayne , Pitts William
Published: May 2005

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Syntheses and Antibacterial Activity of a Series of 3‐(Pyridine‐3‐yl)‐2‐oxazolidinone.
Authors: Cui Yingjie , Dang Yaxian , Yang Yushe , Zhang Shuhua , Ji Ruyun
Published: May 2005

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Synthesis and Tuberculostatic Activity of Some 2‐Piperazinemethylene Derivatives 1,2,4‐Triazole‐3‐thiones (VII)
Authors: Foks Henryk , Janowiec Mieczyslaw , Zwolska Zofia , Augustynowicz‐Kopec Ewa
Published: May 2005

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Synthesis and Antibacterial Activity of 2,4,6‐Tri‐substituted s‐Triazines.
Authors: Srinivas K. , Srinivas U. , Rao V. Jayathirtha , Bhanuprakash K. , Kishore K. Hara , Murty U. S. N.
Published: May 2005

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Pyridazine Derivatives and Related Compounds. Part 12. Synthesis of Some Pyridazino[4′,3′:4,5]thieno[3,2‐d]‐1,2,3‐triazines.
Authors: Deeb Ali , Kotb Mahmoud , El‐Abbasy Mohamed
Published: May 2005

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1,2,4‐Benzothiadiazine Derivatives as α1 and 5‐HT1A Receptor Ligands.
Authors: Tait Annalisa , Luppi Amedeo , Franchini Silvia , Preziosi Elisa , Parenti Carlo , Buccioni Michela , Marucci Gabriella , Leonardi Amedeo , Poggesi Elena , Brasili Livio
Published: May 2005

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1,4‐Diazapane‐2,5‐diones as Novel Inhibitors of LFA‐1.
Authors: Wattanasin Sompong , et al. et al.
Published: May 2005

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New Antiproliferative Benzoindolinothiazepines Derivatives.
Authors: Laconde Guillaume , Depreux Patrick , Berthelot Pascal , Pommery Nicole , Henichart Jean‐Pierre
Published: May 2005

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Syntheses of 1,5‐Benzothiazepines. Part 31. Syntheses and Antimicrobial Studies of 10‐Substituted‐7‐ (monochlorophenyl/dichlorophenyl)‐6H‐6a,7‐dihydro‐6‐phenyl [1]benzopyrano[3,4‐c][1,5]benzothiazepines.
Authors: Pant Umesh C. , Dandia A. , Chandra Hem , Goyal Shweta , Pant Seema
Published: May 2005

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The Study of Intramolecular Tandem Radical Cyclizations of Acylsilanes with Radicalphiles Attached on Silicon.
Authors: Tang Kuo‐Hsiang , Liao Fang‐Yu , Tsai Yeun‐Min
Published: May 2005

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An Efficient Catalytic Enantioselective Fluorination of β‐Ketophosphonates Using Chiral Palladium Complexes.
Authors: Hamashima Yoshitaka , Suzuki Toshiaki , Shimura Yuta , Shimizu Tadashi , Umebayashi Natsuko , Tamura Toshihiro , Sasamoto Naoki , Sodeoka Mikiko
Published: May 2005

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Two New Triterpenoids from Lawsonia alba
Authors: Siddiqui Bina S. , Kardar Muhammad Nadeem , Khan Shazia
Published: May 2005

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New Clerodane Diterpenoids from Casearia membranacea
Authors: Shen Ya‐Ching , Lee Cheng Lin , Khalil Ashraf Taha , Cheng Yuan‐Bin , Chien Ching‐Te , Kuo Yao‐Haur
Published: May 2005

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Total Synthesis of 3‐Hydroxydrimanes Mediated by Titanocene(III) — Evaluation of Their Antifeedant Activity.
Authors: Justicia Jose , Oltra J. Enrique , Barrero Alejandro F. , Guadano Ana , Gonzalez‐Coloma Azucena , Cuerva Juan M.
Published: May 2005

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Sesquiterpenoids from Cynara scolymus.
Authors: Li Xiaoli , Qian Pingli , Liu Zeyuan , Zhao Yu , Xu Gang , Tao Deding , Zhao Qinshi , Sun Handong
Published: May 2005

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Crystallographic Determination of Stereochemistry of Biologically Active 2′′,3′′‐Dibromo‐7‐epi‐10‐deacetylcephalomannine.
Authors: Jiang Yi , Lin Hai‐Xia , Chen Jian‐Min , Chen Min‐Qin
Published: May 2005

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Synthesis of Argentatin A Derivatives as Growth Inhibitors of Human Cancer Cell Lines in vitro.
Authors: Parra‐Delgado Hortensia , Ramirez‐Apan Teresa , Martinez‐Vazquez Mariano
Published: May 2005

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Synthesis, X‐Ray Crystal Structure and Antiestrogenic Activity of 17‐Methyl‐16,17‐secoestra‐1,3,5(10)‐triene Derivatives.
Authors: Sakac Marija N. , Miljkovic Dusan A. , Penov‐Gasi Katarina M. , Popsavin Mirjana , Klisuric Olivera R. , Stankovic Slobodanka M. , Andric Silvana , Kovacevic Radmila
Published: May 2005

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7α,11β‐Dimethyl‐19‐nortestosterone: A Potent and Selective Androgen Response Modulator with Prostate‐Sparing Properties.
Authors: Cook C. Edgar , Kepler John A.
Published: May 2005

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Design and Synthesis of a New Class of Arginine Analogues with an Improved Anion Binding Site in the Side Chain.
Authors: Schmuck Carsten , Geiger Lars
Published: May 2005

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Synthesis and Establishment of Stereochemistry of the Unusual Polyoxazole—Thiazole Based Cyclopeptide YM‐216391 Isolated from Streptomyces nobilis.
Authors: Deeley Jon , Pattenden Gerald
Published: May 2005

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Dynamic Resolution of α‐Bromo Tertiary Amides for Stereoselective Preparation of Dipeptide Analogues.
Authors: Kim Hyun Jung , Chang Ji‐yeon , Shin Eun‐kyoung , Park Yong Sun
Published: May 2005

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A D,L‐Proline Catalyzed Diastereoselective Trimolecular Condensation: An Approach to the One‐Pot Synthesis of Perhydrofuro[3,2‐b]pyran‐5‐ones.
Authors: Sabitha Gowravaram , Raj Kumar M. , Shashi Kumar Reddy M. , Yadav J. S. , Rama Krishna K. V. S. , Kunwar A. C.
Published: May 2005

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Direct Amino Acid Catalyzed Asymmetric Synthesis of Polyketide Sugars.
Authors: Casas Jesus , Engqvist Magnus , Ibrahem Ismail , Kaynak Betul , Cordova Armando
Published: May 2005

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Stereoselective Glycosylation of exo‐Glycals by Microwave‐Assisted Ferrier Rearrangement.
Authors: Lin Hui‐Chang , Chang Chih‐Chun , Chen Jia‐Yi , Lin Chun‐Hung
Published: May 2005

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Efficient Stereoselective Synthesis of γ‐N‐Glycosyl Asparagines by N‐Glycosylation of Primary Amide Groups.
Authors: Tanaka Hiroshi , Iwata Yuki , Takahashi Daisuke , Adachi Masaatsu , Takahashi Takashi
Published: May 2005

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Remote Participation‐Assisted Synthesis of β‐Mannosides.
Authors: De Meo Cristina , Kamat Medha N. , Demchenko Alexei V.
Published: May 2005

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RCM‐Based Synthesis of a Variety of β‐C‐Glycosides and Their in vitro anti‐Solid Tumor Activity.
Authors: Postema Maarten H. D. , Piper Jared L. , Betts Russell L. , Valeriote Frederick A. , Pietraszkewicz Halina
Published: May 2005

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Synthesis of β‐D‐Glucopyranosides of 6‐Substituted 2‐(Indol‐3‐yl)benzothiazoles.
Authors: Humenik Martin , Kutschy Peter , Valkova Katarina , Horvath Branislav , Kovacik Vladimir , Bekesova Slavka
Published: May 2005

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Sulfonium Triflate Mediated Glycosidations of Aryl 2‐Azido‐2‐deoxy‐1‐thio‐D‐mannosides.
Authors: Litjens Remy E. J. , van den Bos Leendert J. , Codee Jeroen D. C. , van den Berg Richard J. B. H. N. , Overkleeft Herman S. , van der Marel Gijsbert A.
Published: May 2005

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Sulfonamidoglycosylation of Methyl Ribofuranosides: A Novel Approach to Furanosylsulfonamides.
Authors: Colinas Pedro A. , Bravo Rodolfo D.
Published: May 2005

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Structural Revision of Hemsleyadine and New Alkaloids Hemsleyanines A, B from Aconitum hemsleyanium var. circinacum.
Authors: Gao Feng , Wang Feng‐Peng
Published: May 2005

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Actinophyllic Acid, a Potent Indole Alkaloid Inhibitor of the Coupled Enzyme Assay Carboxypeptidase U/Hippuricase from the Leaves of Alstonia actinophylla (Apocynaceae).
Authors: Carroll Anthony R. , Hyde Edward , Smith Jill , Quinn Ronald J. , Guymer Gordon , Forster Paul I.
Published: May 2005

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Synthesis and Acetylcholinesterase Inhibition of Derivatives of Huperzine B.
Authors: Feng Song , Xia Yu , Han Dongmei , Zheng Chunyan , He Xuchang , Tang Xican , Bai Donglu
Published: May 2005

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Reaction of Anabasine with 3‐(1‐Hydroxycyclohexyl)‐2‐propynenitrile: A New Route to Functionalized Anabasine Alkaloids.
Authors: Trofimov Boris A. , Andriyankova Ludmila V. , Tlegenov Rustem T. , Mal'kina Anastasiya G. , Afonin Andrei V. , Il'icheva Lubov N. , Nikitina Lina P.
Published: May 2005

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anti‐Proliferative and anti‐Leukemic Activity of DDE46 (Compound WHI‐07), a Novel Bromomethoxylated Arylphosphate Derivative of Zidovudine, and Related Compounds. Studies Using Human Acute Lymphoblastic Leukemia Cells and the Zebrafish Model.
Authors: Benyumov Alexey O. , Venkatachalam Taracad K. , Grigoriants Olga O. , Vassilev Alexei O. , Tibbles Heather E. , Downs Suzanne , Dumez Darin , Uckun Fatih M.
Published: May 2005

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Synthesis of Racemic 9‐(6‐ and 2,6‐Substituted 9H‐purin‐9‐yl)‐5‐oxatricyclo[4.2.1.03,7]nonane‐3‐methanols, Novel Conformationally Locked Carbocyclic Nucleosides.
Authors: Hrebabecky Hubert , Masojidkova Milena , Holy Antonin
Published: May 2005

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The First Synthesis of (S)‐(+)‐Cacalol.
Authors: Tanikawa Shin , Ono Machiko , Akita Hiroyuki
Published: May 2005

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Synthesis of the Enantiomer of 1α,25‐Dihydroxy Vitamin D3 (Calcitriol) and a Diastereomer of 1α,25‐Dihydroxy Vitamin D3 Differing from Natural Product in Configuration at All but One Asymmetric Carbon Atoms.
Authors: Achmatowicz B. , Przezdziecka A. , Wicha J.
Published: May 2005

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2‐Alkyl‐3,4‐dihydroxy‐5‐hydroxymethylpyridine Derivatives: New Natural Vitamin B6 Analogues from a Terrestrial Streptomyces sp.
Authors: Maskey Rajendra P. , Huth Felix , Gruen‐Wollny Iris , Laatsch Hartmut
Published: May 2005

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Cytosporone E (I): Racemic Synthesis and Preliminary Antibacterial Testing.
Authors: Hall Jeffrey D. , Duncan‐Gould Nathan W. , Siddiqi Nasar A. , Kelly Jennifer N. , Hoeferlin L. Alexis , Morrison Susan J. , Wyatt Justin K.
Published: May 2005

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New Strategies Towards Synthesis of Doxorubicin Analogues.
Authors: Fokt I. , Grynkiewicz G. , Skibicki P. , Przewloka T. , Priebe W.
Published: May 2005

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Halenaquinone and Xestoquinone Derivatives, Inhibitors of Cdc25B Phosphatase from a Xestospongia sp.
Authors: Cao Shugeng , Foster Caleb , Brisson Marni , Lazo John S. , Kingston David G. I.
Published: May 2005

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Synthesis of Nonracemic 3‐Deoxyschweinfurthin B (I).
Authors: Neighbors Jeffrey D. , Beutler John A. , Wiemer David F.
Published: May 2005

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DNA Topoisomerase I Inhibitors from Rinorea anguifera.
Authors: Ma Ji , Jones Shannon H. , Marshall Rebekah , Wu Xihan , Hecht Sidney M.
Published: May 2005

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Truncated Azinomycin Analogues Intercalate into DNA.
Authors: Casely‐Hayford Maxwell A. , Pors Klaus , Patterson Laurence H. , Gerner Clive , Neidle Stephen , Searcey Mark
Published: May 2005

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Benzimidazole Derivatives as Novel Nonpeptide Luteinizing Hormone‐Releasing Hormone (LHRH) Antagonists. Part 2. Benzimidazole‐5‐sulfonamides.
Authors: Li Yingfu , Kataoka Mikayo , Tatsuta Miyuki , Yasoshima Kayo , Yura Takeshi , Urbahns Klaus , Kiba Atsushi , Yamamoto Noriyuki , Gupta Jang B. , Hashimoto Kentaro
Published: May 2005

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1‐Hydroxyalkyl‐3‐phenylthioureas as Novel HDL‐Elevating Agents.
Authors: Coppola Gary M. , Damon Robert E. , Eskesen J. Bruce , France Dennis S. , Paterniti James R. Jr.
Published: May 2005

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Deposition of GaSb Films from the Single‐Source Precursor [t‐Bu2GaSbEt2]2.
Authors: Schulz Stephan , Fahrenholz Sonja , Kuczkowski Andreas , Assenmacher Wilfried , Seemayer Andreas , Hommes Alexander , Wandelt Klaus
Published: May 2005

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Synthesis of CoOOH Nanorods and Application as Coating Materials of Nickel Hydroxide for High Temperature Ni—MH Cells.
Authors: Hu W. K. , Gao X. P. , Geng M. M. , Gong Z. X. , Noreus D.
Published: May 2005

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Hollow Gold and Platinum Nanoparticles by a Transmetalation Reaction in an Organic Solution.
Authors: Selvakannan P. R. , Sastry Murali
Published: May 2005

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Anhydrous Solution Synthesis of Germanium Nanocrystals from the Germanium(II) Precursor Ge[N(SiMe3)2]2.
Authors: Gerung Henry , Bunge Scott D. , Boyle Timothy J. , Brinker C. Jeffrey , Han Sang M.
Published: May 2005

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Boring Deep Cylindrical Nanoholes in Silicon Using Silver Nanoparticles as a Catalyst.
Authors: Tsujino Kazuya , Matsumura Michio
Published: May 2005

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Novel Synthetic Route to Biomorphic Al2O3 Ceramics.
Authors: Rambo Carlos R. , Sieber Heino
Published: May 2005

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In vitro Antifungal Properties, Structure—Activity Relationships and Studies on the Mode of Action of N‐Phenyl, N‐Aryl, N‐Phenylalkyl Maleimides and Related Compounds.
Authors: Zacchino Susana A. , et al. et al.
Published: May 2005

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Synthesis of 2,4,6‐Trisubstituted Triazines as Antimalarial Agents.
Authors: Agarwal Anu , Srivastava Kumkum , Puri S. K. , Chauchan Prem M. S.
Published: May 2005

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Identification of Putative Metabolites of Docosahexaenoic Acid as Potent PPARγ Agonists and Antidiabetic Agents.
Authors: Yamamoto Keiko , Itoh Toshimasa , Abe Daijiro , Shimizu Masato , Kanda Tomoatsu , Koyama Takatoshi , Nishikawa Masazumi , Tamai Tadakazu , Ooizumi Hiroshi , Yamada Sachiko
Published: May 2005

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Structure—Activity Relationship Studies on ortho‐Substituted Cinnamic Acids, a New Class of Selective EP3 Antagonists.
Authors: Belley Michel , et al. et al.
Published: May 2005

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Generation of a New Class of hNK2 Receptor Ligands Using the ′Fragment Approach′.
Authors: D'Andrea Piero , Porcelloni Marina , Madami Andrea , Patacchini Riccardo , Altamura Maria , Fattori Daniela
Published: May 2005

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Pyrrolidinohydroquinazolines — A Novel Class of CCR3 Modulators.
Authors: Anderskewitz Ralf , Bauer Rolf , Bodenbach Gisela , Gester Dirk , Gramlich Bernd , Morschhaeuser Gerd , Birke Franz W.
Published: May 2005

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Short‐Range Order and Spin‐Glass‐Like Freezing in A—Mg—R (A: Zn or Cd; R: Rare‐Earth Elements) Magnetic Quasicrystals
Authors: Sato Taku J.
Published: May 2005

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Theoretical Study of the Exchange Coupling in Large Polynuclear Transition Metal Complexes Using DFT Methods
Authors: Ruiz Eliseo
Published: May 2005

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Integrated Nanoscale Electronics and Optoelectronics: Exploring Nanoscale Science and Technology Through Semiconductor Nanowires
Authors: Huang Yu , Lieber Charles M.
Published: May 2005

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Theoretical Methods That Help Understanding the Structure and Reactivity of Gas Phase Ions
Authors: Mercero J. M. , Matxain J. M. , Lopez X. , York D. M. , Largo A. , Eriksson L. A. , Ugalde J. M.
Published: May 2005

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The Performance of Hybrid Density Functionals in Solid State Chemistry
Authors: Cora Furio , Alfredsson Maria , Mallia Giuseppe , Middlemiss Derek S. , Mackrodt William C. , Dovesi Roberto , Orlando Roberto
Published: May 2005

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Al—B—Ti (Aluminum—Boron—Titanium)
Authors: Raghavan V.
Published: May 2005

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Cluster Growing Through Ionic Aggregation: Synthesis and Structural Principles of Main Group Metal—Rich Nitrogen, Phosphorus and Arsenic Clusters
Authors: Driess Matthias , Mulvey Robert E. , Westerhausen Matthias
Published: May 2005

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Heterolytic Splitting of H—H, Si—H, and Other σ Bonds on Electrophilic Metal Centers
Authors: Kubas Gregory J.
Published: May 2005

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Role of the Properties and Structure of Liquid Water in Colloidal and Interfacial Systems
Authors: van Oss C. J. , Giese R. F.
Published: May 2005

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Nanostructured CeO2—ZrO2 Mixed Oxides
Authors: Di Monte Roberta , Kaspar Jan
Published: May 2005

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Methodology Validation and Structure Correction by Total Synthesis: The Case of the Clerodane Diterpenoid, Sacacarin
Authors: Grossman Robert B. , Rasne Ravindra M.
Published: May 2005

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Cyclic π‐ Systems with Anellated Rings: Highly Selective Oxyanion‐Driven Reactions at Chromium Complexes
Authors: Butenschoen H.
Published: May 2005

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Rhodium/Ruthenium Applications
Authors: Sumi Kenzo , Kumobayashi Hidenori
Published: May 2005

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1,3‐Dihydro‐2H‐imidazol‐2‐one Derivatives: Synthesis and Applications
Authors: Zav'yalov S. I. , Ezhova G. I. , Kravchenko N. E. , Kulikova L. B. , Dorofeeva O. V. , Rumyantseva E. E. , Zavozin A. G.
Published: May 2005

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1,3,5‐Triazine: A Versatile Heterocycle in Current Applications of Organic Chemistry
Authors: Giacomelli Giampaolo , Porcheddu Andrea , de Luca Lidia
Published: May 2005

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Recent Progress in Pyridazin‐3(2H)‐one Chemistry
Authors: Lee Sang‐Gyeong , Kim Jeum‐Jong , Kim Ho‐Kyun , Kweon Deok‐Heon , Kang Yong‐Jin , Cho Su‐Dong , Kim Sung‐Kyu , Yoon Yong‐Jin
Published: May 2005

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4‐Alkoxy‐1,1,1‐trichloro‐3‐alken‐2‐ones: Preparation and Applications in Heterocyclic Synthesis
Authors: Martins Marcos A. P. , Cunico Wilson , Pereira Claudio M. P. , Sinhorin Adilson P. , Flores Alex F. C. , Bonacorso Helio G. , Zanatta Nilo
Published: May 2005

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Use of β‐(N,N‐dialkylamino)propiophenones in the Synthesis of Nitrogenated Heterocyclic Compounds
Authors: Abonia R. , Insuasty B. , Quiroga J. , Nogueras M. , Meier H.
Published: May 2005

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Synthesis of 1,2,4‐Triazoles and Thiazoles from Thiosemicarbazide and Its Derivatives
Authors: Mustafa Suni M. , Nair Vipin A. , Chittoor Joshua P. , Krishnapillai Sreekumar
Published: May 2005

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Porphyrins and Related Compounds
Authors: Smith K. M. , Vicente M. G. H.
Published: May 2005

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Quinolizinium Salts and Benzoanalogues
Authors: Ihmels H.
Published: May 2005

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Pyridinones and Related Systems
Authors: Keller P. A.
Published: May 2005

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Highly Enantio‐ and Diastereoselective Syntheses of Axial Chiral Teraryl Compounds
Authors: Schilling Gerhard
Published: May 2005

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Synthetic Eicosanoids
Authors: Wilson Norrie H.
Published: May 2005

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Vinyl and Aryl Halides
Authors: Stanforth S. P.
Published: May 2005

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Quinone Methides as Alkylating and Cross‐linking Agents
Authors: Freccero Mauro
Published: May 2005

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Nitriles: General Methods and Aliphatic Nitriles
Authors: North M.
Published: May 2005

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Ketones: Dialkyl Ketones
Authors: Caprio V.
Published: May 2005

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Aldehydes: α,β‐Unsaturated Aldehydes
Authors: Mackie P. R. , Foster C. E.
Published: May 2005

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Aldehydes: Alkyl Aldehydes
Authors: Handa S.
Published: May 2005

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Recent Progress in Polymeric Palladium Catalysts for Organic Synthesis
Authors: Uozumi Yasuhiro
Published: May 2005

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Molecular Recognition of DNA‐Relevant Molecules by Conformationally Well‐Defined Multitopic Artificial Receptors
Authors: Inouye Masahiko , Takase Masayoshi
Published: May 2005

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The Solid, Liquid and Solution Structural Organization of Imidazolium Ionic Liquids
Authors: Dupont Jairton
Published: May 2005

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Synthesis from Carboxylic Acids and Derivatives by Substitution with a Carbon Nucleophile
Authors: Figadere B. , Franck X.
Published: May 2005

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Synthesis by Reduction of 1,2‐Diketones and α‐Diazoketones, α,α‐Dihetero‐ and α‐Hetero‐substituted Ketones, Enones and Ynones
Authors: Yus M. , Najera C.
Published: May 2005

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Synthesis by Oxidation of Alkenes and Alkanes (excluding Allylic or Benzylic Derivatives)
Authors: Balaban T. S.
Published: May 2005

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Synthesis by Oxidation of Heterosubstituted Alkanes
Authors: von Angerer S.
Published: May 2005

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Aliphatic and Alicyclic Ketones (excluding Cyclobutanones and Cyclopropanones)
Authors: Vogel P.
Published: May 2005

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Introduction to Ketones
Authors: Cossy J.
Published: May 2005

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Recent Advances in the Use of Oxone in Organic Synthesis
Authors: Marcotullio Maria Carla , Epifano Francesco , Curini Massimo
Published: May 2005

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Ions, Radicals, Carbenes, and Other Monocoordinated Systems
Authors: Fairlamb I. J. S. , Dickinson J. M.
Published: May 2005

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Alkynes
Authors: Tyrrell E.
Published: May 2005

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Allenes and Cumulenes
Authors: Bruneau C. , Renaud J.‐L.
Published: May 2005

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Tricoordinate Carbanions, Cations, and Radicals
Authors: Pale P. , Vogel P.
Published: May 2005

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Alkyl Halides
Authors: Kotali A. , Harris P. A.
Published: May 2005

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Thioaldehydes and Thioketones
Authors: Cooper N. J.
Published: May 2005

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Aldehyde and Ketone Functions Further Substituted on Oxygen
Authors: Selden D. A. , Hodgson D. M.
Published: May 2005

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Ketones Bearing an α,β‐Aryl or ‐Hetaryl Substituent
Authors: Aldabbagh F.
Published: May 2005

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Ketones: α,β‐Unsaturated Ketones
Authors: Foster C. E. , Mackie P. R.
Published: May 2005

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Aldehydes: Aryl and Heteroaryl Aldehydes
Authors: Aldabbagh F.
Published: May 2005

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Amidines and N‐Substituted Amidines
Authors: Dunn P. J.
Published: May 2005

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Amides
Authors: Bailey P. D. , Mills T. J. , Pettecrew R. , Price R. A.
Published: May 2005

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Carboxylic Esters and Lactones
Authors: Buckley B. R.
Published: May 2005

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Carboxylic Acids
Authors: Bew S. P.
Published: May 2005

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Acid Halides
Authors: Aldabbagh F.
Published: May 2005

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Palladium‐Mediated Synthesis of Aldehydes and Ketones from Thiol Esters
Authors: Fukuyama Tohru , Tokuyama Hidetoshi
Published: May 2005

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Microwave‐Supported Organic Synthesis: Application. Part 29.
Authors: Keller Walter E.
Published: May 2005

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New C—N and C—C Bond Forming Reactions Catalyzed by Titanium Complexes
Authors: Odom Aaron L.
Published: May 2005

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Highlights: Organocatalysis Gathers Pace
Authors: Clarke Matthew L.
Published: May 2005

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Photoremovable Protecting Groups Based on Electron Transfer Chemistry
Authors: Falvey Daniel E. , Sundararajan Chitra
Published: May 2005

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Synthesis from Aldehydes by Substitution of the Aldehyde Hydrogen
Authors: Figadere B. , Franck X.
Published: May 2005

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Synthesis of the Hamigerans
Authors: Clive Derrick L. J. , Wang Jian
Published: May 2005

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Tartaric Acid and Its O‐Acyl Derivatives. Part 1. Synthesis of Tartaric Acid and O‐Acyl Tartaric Acids and Anhydrides
Authors: Synoradzki Ludwik , Ruskowski Pawel , Bernas Urszula
Published: May 2005

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Asymmetric Synthesis Using Hydrolytic Enzymes in Supercritical Carbon Dioxide.
Authors: Matsuda Tomoko , Harada Tadao , Nakamura Kaoru , Ikariya Takao
Published: May 2005

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Protonated Chiral Catalysts: Versatile Tools for Asymmetric Synthesis
Authors: Bolm Carsten , Rantanen Toni , Schiffers Ingo , Zani Lorenzo
Published: May 2005

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Relay Ring‐Closing Metathesis — A Strategy for Achieving Reactivity and Selectivity in Metathesis Chemistry
Authors: Wallace Debra J.
Published: May 2005

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“Designer Acids”: Combined Acid Catalysis for Asymmetric Synthesis
Authors: Yamamoto Hisashi , Futatsugi Kentaro
Published: May 2005

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Utilization of Water as a Reagent in Regio‐ and Stereoselective Reactions
Authors: Tokunaga Makoto
Published: May 2005

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Novel Synthetic Methods for the Preparation of Optically Active Fluorine‐Containing Building Blocks on the Basis of Sigmatropic Rearrangements
Authors: Konno Tsutomu
Published: May 2005

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Recent Developments in Fluorinated Prostanoids
Authors: Matsumura Yasushi
Published: May 2005

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Synthetic Study on Globomycins Toward the Development of New Antibiotics
Authors: Kiho Toshihiro , Kogen Hiroshi
Published: May 2005

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New Approaches Toward anti‐HIV Chemotherapy
Authors: De Clercq Erik
Published: May 2005

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Chemistry in Crop Protection. Part 2. Nucleoside Chemistry in Crop Protection
Authors: Lamberth Clemens
Published: May 2005

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Synthesis of Benzo[c]phenanthridine Alkaloids Using a Palladium‐Catalyzed Aryl‐Aryl Coupling Reaction
Authors: Harayama Takashi
Published: May 2005

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Non‐Covalent Side‐Chain Polymers: Design Principles, Functionalization Strategies, and Perspectives
Authors: Pollino Joel M. , Weck Marcus
Published: May 2005

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Highly Stable Olefin—Cu(I) Coordination Oligomers and Polymers
Authors: Ye Qiong , Wang Xi‐Sen , Zhao Hong , Xiong Ren‐Gen
Published: May 2005

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Hierarchical Self‐Assembly of Columnar Aggregates
Authors: Keizer Henk M. , Sijbesma Rint P.
Published: May 2005

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Post‐Polymerization Functionalization of Polyolefins
Authors: Boaen Nicole K. , Hillmyer Marc A.
Published: May 2005

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Stimuli Responsive Polymers for Biomedical Applications
Authors: de las Heras Alarcon Carolina , Pennadam Sivanand , Alexander Cameron
Published: May 2005

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2‐Deoxystreptamine: Central Scaffold of Aminoglycoside Antibiotics
Authors: Busscher Guuske F. , Rutjes Floris P. J. T. , van Delft Floris L.
Published: May 2005

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α‐Fluorinated Ethers, Thioethers, and Amines: Anomerically Biased Species
Authors: Leroux Frederic , Jeschke Peter , Schlosser Manfred
Published: May 2005

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BINOL: A Versatile Chiral Reagent
Authors: Brunel Jean Michel
Published: May 2005

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Synthesis of β‐Aminophosphonates and ‐Phosphinates
Authors: Palacios Francisco , Alonso Concepcion , de los Santos Jesus
Published: May 2005

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Conjugate Additions of Nitroalkanes to Electron‐Poor Alkenes: Recent Results
Authors: Ballini Roberto , Bosica Giovanna , Fiorini Dennis , Palmieri Alessandro , Petrini Marino
Published: May 2005

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Concurrent Tandem Catalysis
Authors: Wasilke Julia‐Christina , Obrey Stephen J. , Baker R. Tom , Baza Guillermo C.
Published: May 2005

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Use of O‐Glycosylation in Total Synthesis
Authors: Pellissier Helene
Published: May 2005

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Carbenoids in Enyne Cyclizations
Authors: Hintermann Lukas
Published: May 2005

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The Central Chirality of the Metal Atom and Configurational Relations in Asymmetric Reactions Catalyzed by Metal Complexes
Authors: Pavlov V. A.
Published: May 2005

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From 4,5,6,7‐Tetrahydro‐5‐methylimidazo [4,5,1‐jk](1,4)benzodiazepin‐2(1H)‐one (TIBO) to Etravirine (TMC125): Fifteen Years of Research on Non‐Nucleoside Inhibitors of HIV‐1 Reverse Transcriptase
Authors: De Corte Bart L.
Published: May 2005

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Chemical, Pharmacological and Botanical Studies on Pedalium Murex
Authors: Shukla Y. N. , Khanuja S. P. S.
Published: May 2005

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Stabilization of N‐Compounds in Soil and Organic Matter Rich Sediments: What Is the Difference?
Authors: Knicker Heike
Published: May 2005

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Preparation of Novel Steroids by Microbiological and Combinatorial Chemistry
Authors: Huwe Christoph , Kunzer Hermann , Zorn Ludwig
Published: May 2005

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Total Synthesis of Jatrophatrione, an Unprecedented [5.9.5] Tricyclic Antileukemic Diterpene
Authors: Paquette Leo A.
Published: May 2005

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Alkynyl‐nitrogen and ‐phosphorus Compounds
Authors: Drabowicz J. , Balczewski P. , Szadowiak A. , Zurawinski R. , Mikolajczyk M.
Published: May 2005

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Vinyl and Aryl Metals
Authors: Muthyala R. , Vince R.
Published: May 2005

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Alkylnitrogen Compounds: Compounds with N—N, N—P, N—As, N—Sb, N—Bi, N—Si, N—Ge, N—B, and N—Metal Functional Groups
Authors: Belen'kii L. I.
Published: May 2005

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Ketenimines and Their P, As, Sb, and Bi Analogues
Authors: Aitken R. A.
Published: May 2005

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Polyene Multidrug Resistance Reversal Agents
Authors: Andrus Merritt B.
Published: May 2005

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Synthetic Transformations of Porphyrins: Advances 2002—2004
Authors: Senge Mathias O. , Richter Julia
Published: May 2005

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Lipase‐Catalyzed Preparation of Enantiomerically Enriched Odorants
Authors: Abate Agnese , Brenna Elisabetta , Fuganti Claudio , Gatti Francesco G. , Serra Stefano
Published: May 2005

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The Total Synthesis of (‐)‐Arisugacin A
Authors: Hsung Richard P. , Cole Kevin P.
Published: May 2005

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Stereoselective Synthesis with the Help of Recombinant Enzymes
Authors: Rao Nagaraj N. , Liese Andreas
Published: May 2005

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Organofullerene Materials
Authors: Tagmatarchis Nikos , Prato Maurizio
Published: May 2005

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One or More C:C Bond(s) by Elimination of Hydrogen, Carbon, Halogen, or Oxygen Functions
Authors: Piva O.
Published: May 2005

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One or More CC Bonds Formed by Addition: Addition of Carbon Electrophiles and Nucleophiles to CC Multiple Bonds
Authors: Armstrong A. , Convine N. J.
Published: May 2005

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One or More CC Bond(s) Formed by Substitution: Substitution of Chalcogen
Authors: Hoffmann N.
Published: May 2005

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One or More CC Bond(s) Formed by Substitution: Substitution of Halogen
Authors: Santelli M. , Ollivier C.
Published: May 2005

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9p21 locus analysis in high‐risk gastrointestinal stromal tumors characterized for c‐kit and platelet‐derived growth factor receptor α gene alterations
Authors: Perrone Federica , Tamborini Elena , Dagrada Gian Paolo , Colombo Federica , Bonadiman Lorena , Albertini Veronica , Lagonigro Maria Stefania , Gabanti Elisa , Caramuta Stefano , Greco Angela , Torre Gabriella Della , Gronchi Alessandro , Pierotti Marco Alessandro , Pilotti Silvana
Published: May 2005

BACKGROUND

Gastrointestinal stromal tumors (GISTs) are noncomplex sarcomas that often are due to c‐kit‐activating and platelet‐derived growth factor receptor α gene (PDGFRα)‐activating mutations and perturbations of their related signaling pathways. Molecular and cytogenetic findings have indicated correlations between tumor progression and high‐risk GISTs with c‐kit mutations, the overexpression of genes such as ezrin, and losses at 9p. In particular, it was reported recently that malignant GISTs showed alterations in the p16INK4a gene located at the 9p21 locus.

METHODS

To assess the involvement of p14ARF and p15INK4b in addition to p16INK4a in GISTs, the authors undertook a molecular and cytogenetic study of the 9p21 locus. A series of 22 pre‐Gleevec era, cryopreserved, high‐risk GISTs that were characterized well in terms of KIT and PDGFRα receptors were investigated for mRNA expression, homozygous deletions, mutations, and promoter methylation of locus 9p21, in some instances complemented by fluorescent in situ hybridization studies.

RESULTS

The results indicated the loss of p16INK4a mRNA expression in 41% of the GISTs, mainly due to the homozygous deletion of both the p16INK4a gene and the p14ARF gene (24%). No mutations were found, and promoter methylation (detected by means of methylation‐specific polymerase chain reaction analysis in 27% of tumors) was restricted mainly to the p15INK4b gene (20%). It is noteworthy that, in all of the methylated GISTs, the epigenetic promoter alteration was coupled with mRNA expression.

CONCLUSIONS

Alterations in the 9p21 locus were found cumulatively in 54% of the tumors in the current series and were represented mainly by the loss of tumor suppressor gene expression. The p16INK4a deletion, which always was coupled with p14ARF gene loss, seemed to be the most common 9p21 inactivation mechanism. Cancer 2005. © 2005 American Cancer Society.