bluuebunny/crossref_metadata_2025 huggingface dataset:
ONLINE GAME ADDICTION BEHAVIOR: GENDER AND DURATION OF PLAYING ONLINE GAMES IN ADOLESCENTS
Authors: Sari Novita , Maulidya Rizki , Afriani Afriani
Published: June 2023

Adolescents advantage online games as an escape from the problems they have in the real life. The various types of online games make adolescents feel challenged so that thet spend a long time playing online games. This online game phenomenon that occurs in adolescents causes online game addiction behaviour. Men are much more likely to play online game so they tend to have higher rates of online game addiction behaviour than do women. This study aims to reveal the sex differences and duration of playing online game affect online game addiction behaviour. This study used a quantitative approach through purposive sampling with a total sample size of 336 adolescents. The research data were analyzed using Linear Regression Analysis. The result showed that sex differences and duration of playing game online affect to online game addiction behaviour.
Artificial Intelligence: Current Perspectives and Alternative Paths
Authors: Sanin Cesar
Published: June 2023

Artificial Intelligence (AI). Impossible not to talk about it since the last release from OpenAI of GPT-4 in March 2023 making once again AI the buzzword of the moment.  This is bigger than the day Deep Blue won against Garry Kasparov in 1997, or the day IBM Watson won Jeopardy in 2011.  OpenAI and its artificial intelligence latest advance is now at the hands of every person with access to internet; ChatGPT has democratized AI, and everyone can “play” with it.  Now at the hands of everyone and despite the great advances shown, models using GPT-4 technology such as ChatGPT or Bing Chatbot are under scrutiny for performance, human-like “intelligence”, and user experience.
AHP-TOPSIS para el diseño de redes de sensores inalámbrica con topología tipo clúster con nodos sensores en tierra y nodo sumideros instalado en un vehículo aéreo no tripulado
Authors: Camargo-Ariza Luis Leonardo , Gasca-Mantilla Maira Cecilia , Castrillo-Fernandez Luis Jose
Published: June 2023

Las redes inalámbricas de sensores regularmente están formadas por numerosos nodos con baja capacidad de energía, comunicación, procesamiento y almacenamiento. El diseño de estas redes presenta desafíos relacionados con el consumo energético, latencia y modo de recolección de la información. La configuración de los nodos en clústeres y el uso de vehículo aéreo no tripulado como nodo recolector mejora el rendimiento energético de la red y facilita la recopilación de los datos. Sin embargo, se requiere de la selección de un nodo líder de clúster que concentre los datos recolectados por los otros nodos y los reenvíe al equipo móvil en el aire. El objetivo de este trabajo consiste en la selección del nodo líder de clúster que optimice el rendimiento de la red. Para la selección se aplica métodos de toma de decisiones multicriterio. Primero se emplea el proceso analítico jerárquico para identificar la prioridad de los criterios empleados en la toma de decisión. Posteriormente, se emplea la técnica para el orden de preferencia por similitud con la solución ideal para la selección del nodo líder. Como resultado se obtiene el vector de prioridades de los criterios: energía residual 56.51%; nivel de intensidad de señal recibida 27.2%, energía empleada en la transmisión 10.38%, y número de nodos vecinos 5.91%. Además, se propone el algoritmo para optimizar la selección del nodo líder en el clúster.
Optimization of Extraction Lannea coromandelica for Antioxidant Activity using Analytical Factorial Design Approach
Authors: AR Muh. Azwar , Hikma Nurul , Yasir Budiman , Asril Burhan Asril , Khairuddin Khairuddin
Published: June 2023

Background: The yield of active compound in a plant can be affected by the extraction method, such as variety of solvent and extraction technique used. Objectives: This study aimed to optimize the yield of Lannea coromandelica leaf extract using several types of solvent and extraction techniques and evaluate the antioxidant activity of the extracts. Material and Methods: This study used a variety of solvent like distilled water, ethanol, n-hexane, and ethyl acetate with maceration, reflux, and sonication extraction techniques. The extract obtained was calculated for the percent yield and analyzed for their antioxidant activity using the DPPH method by UV -Vis Spectrophotometry with 523.5 nm maximum wavelength. The antioxidant activity was analyzed by factorial design analysis in Minitab 21 software. Results: The highest percentage yields was obtained from the extract with ethanol solvent, followed by distilled water, ethyl acetate and n-hexane. The highest extraction techniques was obtained from reflux and followed by maceration and sonication extracts. Analytical factorial design analysis showed that the linearity of solvent variation and extraction technique had a significant effect (P>0.05). From the analysis, it was found that there was a significant difference between the effect of the solvent on the antioxidant activities compared to the extraction technique. The extracts obtained have a very strong antioxidant activity against DPPH radicals. T Conclusions: L. coromandelica plant aquadest extract has potential to be developed in optimalization extraction method.
Agricultural financing risk and ib agricultural financing: A long relationship
Authors: Alan Nur Muhammad , Honesty Nur Firdaus  , Armanto Andre , Herianingruma Sri
Published: June 2023

Indonesia is destined to be an agrarian country because of its location on the equator, unfortunately not all farmers are able to access capital for their agricultural businesses while the contribution of the agricultural sector to employment is very high. It is also important to consider that Indonesia is also a country with the largest Muslim population in the world, so there should be a financing scheme in the agricultural sector that is in accordance with sharia compliance. Therefore, Islamic banking should be present to provide capital to farmers who need agricultural financing without violating sharia provisions. Identifying variables that affect Islamic bank financing in the agricultural sector in the long run is the aim of this study so that our findings can be one of the considerations for policy makers for future policies. To reveal the purpose of our research, we consider the factors affecting the agricultural financing of Islamic banks which consist of the risk of agricultural financing, farmer welfare, inflation and economic growth with observations for a decade from 2012 to 2021 on a quarterly basis. By using ARDL estimation, our findings find that in the long run relationship the welfare of farmers has no effect, while the other remaining variables have a significant effect. This study offers valuable implications indicating that the presence of Islamic banking can be considered as a viable financial solution within the agricultural sector.
Microplastics ingestions by wild and aquaculture marine bivalves: A systematic review on field investigation study
Authors: Saraswati Ni Luh Gede Rai Ayu
Published: June 2023

Plastics degradation has resulted in a major threat to marine organisms, including bivalves. Thirty-three peer-reviewed papers have been reviewed to understand the geographical spread of microplastics ingestion by marine bivalves, characteristics of microplastics ingested, and limitation of microplastics analysis globallly. Only studies on microplastics investigation in marine bivalves from wild and aquaculture area were selected. Marine bivalves are reported to accumulate microplastics from all marine environment compartments. High proximity area with intensive human activities is suggested to increase the uptake of microplastics by the bivalves. Microfibers and fragments are the common types of microplastics ingested by the bivalves around the world, with various sizes (0.45µm – <45mm) and number of particles per individual (20 – ~175 particles/individual). However, there is uncertainty when comparing the findings from one study to another due to the absence of international standard protocol and microplastics data base. Therefore, this limitation should be addressed prior to monitoring microplastics accumulation in marine bivalves.
Analysis of electrostatic precipitators plate-wire type in reducing dust emissions for sustainable environment
Authors: Rahman Herliati , Hidayaturrahman Cepy
Published: June 2023

The current global environmental trend is that the world has agreed to go towards net zero emissions. Consequently, waste-producing-industries must comply with these provisions to achieve the mission of sustainable development and green production, including cement industry. This study aims to investigate the factors that affect the performance of the Electrostatic Precipitator (EP) as a dust collector in grinding cement raw materials. The method used was measuring the static-dynamic pressure at the poking hole closest to the EP inlet, measuring EP efficiency using the Matts-Ohnfeldt equation based on secondary data obtained from the Crane Information Management System (CIMS), and calculating the corona power to determine how strong the ion space is created between the discharge electrode and collecting electrode and determine the critical voltage and application voltage needed to generate the corona. The observations and calculations show that several factors can affect EP performance, such as inlet temperature gas discharge, concentration of dust from the chimney, and maximum concentration of chimney outlet. The maximum temperature gas discharge that EP can accept is 105°C. The maximum concentration of chimney outlet dust is 50 mg/Nm3 and maximum CO concentration is 2000 mg/m3.
A study on sound stimulation using an individual’s heart rate to improve the stability and homeostasis of the autonomic nervous system: breathing support
Authors: daechang kim , Kim Nahyeon , LEE Younju , Kim Sumgmin , Kwon Jiyean
Published: June 2023

Objectives: In this study, we explain the role of respiratory support by
proposing aHRSR, a sound stimulation to prevent imbalance of ANS due to
dynamic movement. The function and role of aHRSR was analyzed through
the time and frequency domain of HRV using PPG data of 22 participants
(DUIRB-202109-12). Method: Changes in the ANS were confirmed using SDNN
and LF, which represent total ANS activity, and the correlation between
the stimulation effect of aHRSR and respiration was analyzed using RMSSD
and HF, which included parasympathetic nervous system and respiratory
frequency. Results : As an effect of aHRSR on dynamic movement, the
recovery time of RR interval was advanced by about 15 seconds, SDNN
increased from 44.16 to 47.85 ms, and RMSSD increased from 23.73 to
31.89 ms, increasing the stability of the ANS and reducing instability.
Also, by reducing the change rate of LF from -13.83 to -8.83 % and the
rate of change of HF from 10.59% to 3.27%, the effect of homeostasis
of the ANS according to aHRSR is also shown. In other words, aHRSR
decreased HF including respiratory energy and increased RMSSD generated
during stimulation of the parasympathetic nervous system. Conclusions :
These results suggest that aHRSR can stimulate the parasympathetic
nervous system with minimal changes in breathing by assisting breathing
that occurs during dynamic movement.
Research of Aging Test on High Tg Colorless Polyimide
Authors: Liu Ji , Jiang Sirui , Li Fu , Chen Cheng
Published: June 2023

The colorless polyimide (CPI) has been drawn much attention for its
application in transparent electronics, such as the camera under panel
(CUP) in organic light-emitting diode display (OLED) display which
required a high transmittance (Tr%). The high temperature (even to
450℃) process of the preparation of OLED device may have huge challenges
on the properties of CPI, so we designed a series of aging test
experiments to study the influence of test temperature and atmosphere on
the Tr% of CPI films with structure of Glass/SiO2/CPI/SiO2. With the
increasing of aging temperate from 430℃ to 450℃ and 470℃, the Tr% of
the film decrease obvious, especially responding the wavelength from
400nm to 600nm. The samples with aging test all had a low Tr% than the
sample without aging. Comparing with the sample without aging, the loss
transmission were 0.22%, 1.42% and 4.82% for the films aging with
430℃, 450℃ and 470℃ in N2 atmosphere, respectively. Meanwhile, the
influence of aging atmosphere on the Tr% was also researched with
nitrogen and air. The film aging with nitrogen had a higher Tr% than
that aging with air, the loss transmission were 1.22% and 1.42%
compared with the sample without aging test.
Unraveling the effects of species intra- and interspecific interactions and environmental factors on the spatial pattern of the tertiary relict plant Tetracentron sinense Oliver
Authors: Zhang Huan , Hongping Deng , Gan Xiaohong
Published: June 2023

The spatial pattern is critical for understanding the plant population
status. The distribution patterns of endangered plants are more
vulnerable to intraspecific, interspecific, and environmental factors.
Tetracentron sinense Oliver, a tertiary relict plant, the spatial
pattern, and its influencing factors are poorly understood. We sought to
figure out the spatial pattern of T. sinense and the factors responsible
for this pattern. We utilized the point pattern, ordinary kriging, and
canonical correlation analysis to identify distribution patterns,
spatial interactions, and environmental factors. The results revealed
that T. sinense individuals were highly aggregated, at a small scale.
Similarly, there was a positive correlation between young and adult
trees at smaller scales. In addition, the dominant species showed a
positive correlation with T. sinense; the correlation gradually became
non-significant or negative as the scale increased. Furthermore, the
main environmental factors affecting the distribution of T. sinense were
air humidity, altitude, litter depth, and potassium content. These
results highlighted the importance of intra- and interspecific
interaction and environmental factors for the spatial distribution of T.
sinense. Our results provide new insights into endangered species’
spatial patterns and main factors. Moreover, these findings have
relevant implications for conserving and managing endangered trees in a
constantly fragmented habitat.
A One-Pot Synthesis of Axially and Centrally Chiral A-type Nanogrids
Authors: Wei Ying , Du Xue , Huang WanXin , Fu MingYang , Zhang Zheng , Zhong ChunXiao , WANG Yiru , Ling Haifeng , Xie Linghai , Huang Wei
Published: June 2023

A novel type of A-type nanogrids (AGs) with axial and central chirality
was synthesized via Friedel-Crafts gridization of thiophenes and
difluorenyl biaromatic derivatives, yielding 9–30%. Additionally, the
effect of stereoisomers of 1,1’-binaphthyl difluorenols (BINDFOH) was
investigated to demonstrate that R/S-BINDFOH is more advantageous for
the synthesis of AGs than Mix-BINDFOH. Furthermore, Tests on OFET memory
devices showed that AGs have a larger storage window, indicating
potential for data storage applications.
Double-Orifice Mitral Valve: Diagnosis and Characterization with Three-Dimensional Transesophageal Echocardiography
Authors: Sharkey Aidan , Bose Ruma , Rehman Taha A. , Khan Adnan Ali , Saeed Shirin , Mahmood Feroze
Published: June 2023

Double orifice mitral valve is a rare congenital anomaly that is often
associated with other congenital cardiac abnormalities. Patients may
present with valvular dysfunction or may be asymptomatic and have an
incidental diagnosis of double outlet mitral valve. Whether symptoms due
to this pathology are present or not, it is important to accurately
characterize this lesion. 3-dimensional imaging is a powerful diagnostic
modality for diagnosing and characterizing lesions such as this as
highlighted in this case image series.
Interim PET-CT: Predictive marker and therapeutic modification tool of pediatric Hodgkin lymphoma
Authors: Dwivedi Pankaj , Mathankar Manish , Bongulwar Chaitali , Modak Ketan , Chakraborty Madhabika , Kapse Atul , Pangarkar Meena , Manvani Nitin
Published: June 2023

Hodgkin lymphoma is a haematolymphoid malignancy seen in pediatric and
adult age groups with an excellent outcome. The current priority of the
treatment has been a reduction of acute and chronic morbidities without
compromising outcomes. PET-CT scan is an integral component in
prognosticating and determining outcomes in Hodgkin lymphoma. Recent
studies have highlighted the role of interim PET-CT scan in choosing
future therapy. The evidence to support the role of interim PET-CT scan
in childhood Hodgkin lymphoma is limited. The aim of the study is to
analyse the role of interim PET-CT in the management of childhood HL,
and to investigate survival outcomes of children treated at our
institute. This is a retrospective study and included all the children
with HL treated at our institute in last five years. All the children
were treated as per ESMO guidelines. Interim PET-CT scan was done after
two cycles of chemotherapy. The correlation of various possible risk
factors with the outcomes was examined. Only the interim PET/CT findings
were associated with the results. At median follow-up of 34 months, the
event free survival (EFS) was 95.7% and overall survival (OS) was
100%. Interim PET-CT plays an important role in treatment modification
without compromising on the outcomes in children with HL. Survival rates
were consistent with those reported in published literature.
A Taxonomy on Vertical Handover for Telecommunications Systems
Authors: Umeonwuka Obumneme Obiajulu , Njoku Franklin , Tekanyi Abdoulie M. S. , Usman Aliyu Danjuma , Yaro Abdulmalik Shehu
Published: June 2023

Wireless networks have become increasingly popular in recent decades for
both residential and commercial networking. Currently, people use smart
mobile devices that are fitted with a range of wireless networking
interfaces to conduct short-term or long-term business, connect,
socialize, and browse the Internet. Because wireless technologies and
mobile devices have made amazing advancements, users need smooth,
continuous, and faultless services with Quality of Service (QoS) from
every origin to device at any given time while on the go or stationary.
In order to accommodate the increasing traffic demands and service
requirements, the next generation of wireless infrastructures (5G)
paradigm will feature a high deployment of base stations and a variety
of RATs, including Wireless Local, Metropolitan and Wide Area Networks
(WLAN, WMAN, WWAN), Long Term Evolution (LTE), and Wireless Broadband
(WiBro). However, no single RAT can simultaneously provide mobile users
with high bandwidth, low latency, widespread coverage, and high QoS
levels. Hence, this book chapter seeks to elucidate the varying kinds of
vertical handover techniques that could be adopted to meet the demands
of mobile users based on QoS and QoE.
Global research performances on water footprint: A review and bibliometric analysis
Authors: junlin ren , ziqian Peng , Xuemei Zeng
Published: June 2023

The purpose of this study is to outline global performance and to
quantitatively evaluate the current research field hot spots, and the
future trends about the water footprint. Bibliometric methods are used
to analyze 861 records retrieved from the collection of Web of Science
Core (WoS). The performance of publications, categories, countries,
institutes, research hot spots, and trends is analyzed in this study by
applying CiteSpace and VOSviewer tools. The results revealed that
publications about water footprint have experienced two stages: a stable
rising period and a rapid rising period. The research pertaining to
water footprint is mainly in the fields of virtual water, water use
efficiency, water scarcity, water pollution, etc. The People’s Republic
of China, The United States of America, Iran, New Zealand, and Italy get
higher rankings in paper output, and the Chinese Acad of Sciences,
Beijing Normal University, Northwest A&F University, Beijing Forestry
University, University of Twente and Hohai University achieve a high
ranking on water footprint research. In addition, further studies in
research frontiers have revealed that climate change, sustainable
agriculture, and water conservation will become popular directions and
trends in water footprint research.
Study on the therapeutic effect and mechanism of traditional Chinese medicine liquid drip vocal cords on vocal disorders in singing
Authors: Xu Honglei
Published: June 2023

This article explores the effectiveness of traditional Chinese medicine
liquid drip therapy in treating and caring for vocal disorders in
singing. Through various statistical methods, the optimal treatment and
care durations for different voice disorders and singing groups were
determined, and the acting mechanism of the treatment was revealed.
Results showed that Chinese medicine liquid drip therapy is highly
effective and safe in treating and caring for various vocal disorders.
For vocal music major students, vocal music teachers, and actors with
vocal cord edema, polyps, nodules, cysts, hoarseness, vocal fatigue, and
other symptoms, the best treatment and care durations were found to be
14 days and 5 days, respectively. This research provides a theoretical
basis and data support for promoting the use of traditional Chinese
medicine liquid drip therapy for vocal health.
Prevalence of influenza and other acute respiratory illnesses in patients with acute myocardial infarction in Bangladesh: a cross-sectional study
Authors: Aleem Mohammad , Chughtai Abrar , Rahman Bayzidur , Akhtar Zubair , Chowdury Fahmida , Qadri Firdausi , MacIntyre C.Raina
Published: June 2023

Background: Several studies imply that influenza and other respiratory
illness could lead to acute myocardial infarction (AMI), but data from
low-income countries are scarce. We investigated the prevalence of
recent respiratory illnesses and confirmed influenza in AMI patients,
while also exploring their relationship with infarction severity as
defined by ST-elevation MI (STEMI) or high troponin levels. Methods:
This cross-sectional study, held at a Dhaka tertiary hospital from May
2017 to October 2018, involved AMI inpatients. The study examined
self-reported clinical respiratory illnesses (CRI) in the week before
AMI onset and confirmed influenza using baseline qRT-PCR. Results: Of
744 patients, 11.3% reported a recent CRI, most prominently during the
2017 influenza season (35.7%). qRT-PCR testing found evidence of
influenza in 1.5% of 546 patients, with all positives among STEMI
cases. Frequencies of CRI were higher in patients with STEMI and in
those with high troponin levels, although these associations were not
statistically significant after adjusting for other variables. The risk
of STEMI was significantly greater during influenza seasons in
unadjusted analysis (RR: 1.09, 95% CI: 1.02- 1.18), however, this
relationship was not significant in the adjusted analysis (aRR: 1.03,
95% CI: 0.91- 1.16). Conclusions: In Bangladesh, many AMI patients had
a recent respiratory illness history, with some showing evidence of
influenza. However, these illnesses showed no significant relationship
to AMI severity. Further research is needed to understand these
associations better and to investigate the potential benefits of
infection control measures and influenza vaccinations in reducing AMI
incidence.
Experiences and Expectations of Outpatient nurses after the changed measures for COVID-19 prevention and control：A Qualitative Study in China
Authors: JI Juan , Zhang Yin-ying , Xu Xue-mei , Gu Yue-lan , Wei Hong , Yang Yi-qun , Gu Jie
Published: June 2023

Introduction: The novel corona-virus outbreak three years ago
has changed people’s lives, with different responses around the world.
As the largest developing country, China has taken strict prevention and
control measures against this endemic. Although it is not very
convenient, people have been used to such prevention and control
methods. In December, 2022, China changed the prevention and control
measures, a large number of patients were infected in a short period of
time. Outpatient department acted as the first line of the hospital, and
outpatient nurses acted as fighters, facing great difficulties and
psychological pressure.In-depth understanding of the real experience of
outpatient nurses after the change of COVID-19 prevention and control
measures in China will provide reference for further improving the
management level of emergency nursing. Methods: From December
2022 to January 2023, in the initial stage of the change of endemic
prevention measures, 16 outpatient nurses from the First Affiliated
Hospital of Soochow University conducted semi-structured interviews, and
analyzed the interview data by Colaizzi analysis. Results:
Based on the real experience of 16 outpatient nurses in this special
period, four themes were extracted. The themes were the
following:(1)Ethical challenges; (2)Changes in life; (3)Get experience,
normalize, and adapt to the endemic; (4)Re-understanding for work and
life. The suggestions were the following:(1)Pay more attention to the
emotional changes of the outpatient nurses, and give them psychological
support; (2)Strengthen the social support system and provide good
logistics support; (3)Improve the management system, and pay attention
to the suggestions and reflections of medical staff.
Conclusion: Through this interview, it was discovered that
outpatient nurses demonstrated a strong sense of responsibility and
mission during the process of epidemic prevention policy changes.
However, they also experienced negative psychological effects due to
inadequate understanding of the disease, heavy treatment tasks, and risk
of self-infection. Therefore, managers should optimize human resource
allocation, promptly alleviate negative emotions among outpatient
nurses, and provide them with psychological counseling services.
Strengthening the Societal Pillars for effective management of sickle cell disease
Authors: Kumar Ravindra , Patel Deepika , Rao Ekta , Saxena Nishant
Published: June 2023

Sickle cell disease (SCD) is a common inherited blood disorder of public
health concern in India. Individuals with SCD may encounter stigma,
discrimination, and misconceptions about their condition, leading to
feelings of isolation and frustration. It is important to note that the
psychological impact of SCD can vary among individuals. Some may develop
resilience and coping strategies to manage the challenges, while others
may require additional support from healthcare professionals,
psychologists, or support groups to address their psychological needs.
The multidisciplinary approach involving medical care, psychological
support, and social interventions is crucial in improving the overall
well-being of individuals living with sickle cell disease. While the
clinical aspects of SCD are significant, it’s also important to consider
the psychological aspects that can affect individuals with the
condition. In this context, there is a pressing need for societal
support pillars which empower SCD patients and improves their quality of
life. In this context, there is a pressing need for societal support
pillars which empower SCD patients and improves their quality of life.
The impact of societal support pillars on SCD patients is substantial.
Strengthening healthcare systems, fostering robust social support
networks, facilitating inclusive educational environments, and raising
public awareness are integral components of comprehensive care for
individuals living with SCD. All these pillars can significantly improve
the quality of life and outcomes for SCD patients, ultimately leading to
a more inclusive and supportive society.
Revolutionizing Family Healthcare: Examining the Benefits and Obstacles of E-Health
Authors: Görgü Genco , Çöme Oğulcan , Mevsim Vildan
Published: June 2023

Abstract This review explores the challenges and barriers
associated with the implementation of e-health initiatives in primary
care settings. It identifies several key factors that hinder the
widespread adoption of e-health applications, including the lack of
adequate awareness of medical informatics and e-health’s role in
healthcare development, insufficient evidence on their effectiveness,
difficulties in meeting the costs of developing and implementing
e-health infrastructure, and the marginalization of the private sector
and private health institutions. Furthermore, the review highlights
issues such as low health and informatics literacy among society, the
weakness of laws and regulations on the provision of e-health services,
and the lack or weakness of qualified human resources. It also
emphasizes the need for addressing these challenges through
evidence-based strategies, collaboration between stakeholders, improved
education and training, and the development of comprehensive legal
frameworks. By overcoming these obstacles, the review suggests that
e-health has the potential to enhance healthcare delivery, improve
patient outcomes, and contribute to achieving broader public health
goals.
A 14.5 μVrms 2.55 μ W Fully Integrated CMOS Preamplifier for Non-Invasive Wearable Electrocardiogram Sensor Applications
Authors: Gupta Krishna , Tyagi Shivaji
Published: June 2023

In this paper, a noise and power-optimized fully-differential capacitive
feedback CMOS preamplifier circuit is designed using a commercial 0.35
μm CMOS technology node. The designed preamplifier circuit is
part of an analog front-end SoC, which monitors the human
electrocardiogram (ECG) using dry electrodes. The transistors in the
interface circuit are biased in weak inversion region for lower total
input referred noise and power dissipation respectively. With an input
referred noise of 14.5 μ V RMS and 2.55 μW power dissipation, the
resultant preamplifier achieves a gain of 52dB over a bandwidth range of
0.003 Hz to 880 Hz with Noise Efficiency Factor (NEF) of 2.52.
STUDY OF THE ELECTRO-OSMOTIC PHENOMENON IN THE PERISTALTIC FLOW OF FRACTIONAL SECOND-GRADE FLUID THROUGH A CYLINDRICAL TUBE WITH HEAT AND MASS TRANSFER
Authors: Channakote Mahadev , M Shekar , Abbas Munawwar Ali
Published: June 2023

This study’s ambitious purpose is to examine how rheological effects on
peristaltic activity through a tube and electro-osmotic processes
interact. The Poisson-Boltzmann equation is taken into account to
investigate the electro-kinetic phenomenon. A fractional second-grade
liquid model is used to explain the rheological deeds of the liquid. An
aqueous ionic solution like blood is considered. Using Caputo’s
definition, the problem’s analytical resolution is attained. With a
peristaltic cylindrical tube, the consequences of double-diffusive
convection on the viscoelastic fluid are brought up. To examine the
unique characteristics of pressure rise and friction force, numerical
integration is used. Many regulatory elements’ effects are looked at and
shown in a series of graphs. The significance of the findings lies in
their demonstration that pressure gradient continuously improves as the
exterior electric field’s intensity upsurges. It is as well strong that
the pressure gradient’s negative value can be influenced by how strong
the external electric field becomes. The analysis that is being given is
anticipated to be extremely beneficial in the treatment of tissue
cancer.
Semiclassical states for fractional Schrödinger equations with critical nonlinearities
Authors: lv Ying , Ting-ting Dai , Du Jia-Lu , Ou Zeng-Qi
Published: June 2023

In this paper, we consider the following fractional Schrödinger equation
ε 2 s ( − ∆ ) s u + V ( x ) u = P ( x ) f ( u ) + Q ( x ) | u
| 2 s ∗ − 2 u in R N , where ε>0 is a
parameter, s∈(0 ,1), 2 s ∗ = 2 N N − 2 s ,
N>2 s, ( − ∆ ) s is the fractional Lapalacian
and f is a superlinear and subcritical nonlinearity. Under a
local condition imposed on the potential function, combining the
penalization method and the concentration-compactness principle, we
prove the existence of a positive solution for the above equations.
Effect of treatment with GLP-1R agonists on the urinary peptidome of T2DM patients
Authors: Lohia Sonnal , Siwy Justyna , Mavrogeorgis Emmanouil , Eder Susanne , Thoeni Stephanie , Mayer Gert , Mischak Harald , Vlahou Antonia , Jankowski Vera
Published: June 2023

Type II diabetes mellitus (T2DM) accounts for approximately 90% of all
diabetes mellitus cases in the world. Glucagon-like peptide-1 receptor
(GLP-1R) agonists have established an increased capability to target
directly or indirectly six core defects associated with T2DM, while, the
underlying molecular mechanisms of these pharmacological effects are not
fully known. This exploratory study was conducted to analyze the effect
of treatment with GLP-1R agonists on urinary peptidome of T2DM patients.
Urine samples of thirty-two T2DM patients from the PROVALID study (A
Prospective Cohort Study in Patients with T2DM for Validation of
Biomarkers) collected at pre- and post-treatment with GLP-1R agonist
drugs were analyzed by CE-MS. In total, 70 urinary peptides were
significantly affected by GLP-1R agonist treatment; generating from 26
different proteins. The downregulation of MMP proteases, based on the
concordant downregulation of urinary collagen peptides was highlighted.
Treatment also resulted in downregulation of peptides from SERPINA1,
APOC3, CD99, CPSF6, CRNN, SERPINA6, HBA2, MB, VGF, PIGR and TTR, many of
which were previously found to be associated with increased insulin
resistance and inflammation. The findings indicate potential molecular
mechanisms of GLP-1R agonists in the context of management of T2DM and
prevention or delaying the progression of its associated diseases.
Analysis of voltage control using V2G technology to support low voltage distribution networks.
Authors: Mattos Marina , Archetti Joao , Bitencourt Leonardo , Wallberg Alexander , Castellucci Valeria , Dias Bruno , Oliveira Janaína G.
Published: June 2023

The decarbonization of the power generation and transport sector encourage the analysis of connection of
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DER, such as
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EVs, to the electrical system, as well as the evaluation of their impact on smart cities. A better understanding of the negative impacts on the power systems will lead to propose mitigation measures and eventually revolutionize the way distributed generation works. This paper aims at modeling and evaluating the impact of EVs on a real distribution network. The energy system chosen operates at 60 Hz, 34,5 kV (Medium Voltage) and 0,208 kV (Low Voltage) and it is simulated using PSCAD/EMTDC. To reproduce realistic user consumption profiles, dynamic load profiles based on EV owners behaviour have been simulated. The
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V2G technology is modeled to mitigate the impacts of high penetration of EVs by supporting the network from undervoltage. The results show the importance of active management in modern power systems, especially considering the increase in DER penetration expected for the coming years. This work shows the benefits of implementing V2G technology while highlighting the challenges involved in a real case.
Surgical excision methods for skin cancer involving the nail unit: a systematic review
Authors: Hardie Claire , Wade Ryckie , Wormald Justin , Stafford Brian , Elliott Faye , Newton-Bishop Julia , Dewar Donald
Published: June 2023

Introduction Skin cancer affecting the nail unit is rare but is
associated with morbidity, and melanoma has a high mortality rate. The
principal treatment is surgical excision and methods can be classified
into digit-sparing surgery or amputation. Digit-sparing surgery (wide
excision or Mohs surgery) may be safe and effective for malignancies
involving the nail unit in comparison to amputation if there is not bony
invasion. The objective was to assess the efficacy and safety of
different methods of surgical excision for skin cancer involving the
nail unit. Methods Prospective comparative studies (randomised
controlled, non-randomised controlled and prospective observational
studies) of surgical excision for skin cancer of the nail unit in all
participants were eligible for inclusion. We searched electronic
databases, trials registers and conference abstracts. We checked the
reference lists of included studies and related systematic reviews for
further references to relevant studies, and we contacted experts to
enquire if they were aware of any additional relevant trials. We used
standard methodological procedures expected by Cochrane. The primary
outcomes were overall survival, disease free survival and adverse
events/outcomes at 30 days. The secondary outcomes were quality of life
outcomes. We planned to use GRADE to assess the quality of the evidence
for each outcome. Results We did not identify any studies that met the
inclusion criteria for this review. We have been unable to assess our
outcomes of overall survival, disease free survival, adverse
events/effects and quality of life. Conclusions As we have not
identified any studies for inclusion, we are unable to assess the
efficacy and safety of different methods of surgical excision for skin
cancer involving the nail unit. Prospective research, ideally in the
form of a randomised trial, is required in this field. Registration
Cochrane Database of Systematic Reviews 2021, Issue 5. Art. No.:
CD014590.
Drought-induced vertical displacements and water loss in the Po river basin (Northern Italy) from GNSS measurements
Authors: Pintori Francesco , Serpelloni Enrico
Published: June 2023

We study vertical ground displacement time-series from GNSS stations in
the Po river basin to measure deformation signals associated with the
severe drought occurring since 2021 and estimate the spatial
distribution of water loss. The detection of vertical ground
displacement trend changes allows us to extract a spatially correlated
signal that follows the Po level trend changes and SPEI-12 drought
index. GNSS stations in the basin mostly underwent uplift, up to 7 mm,
since 2021, which corresponds to ~80 Gtons of water
loss. Compared to GLDAS and GRACE, the GNSS results show a similar
temporal evolution of water content, but a different spatial
distribution. Our study indicates that using dense GNSS networks is an
effective way to monitor long-term changes in water storage even in
small water basins and serve as a reliable indicator of drought
severity.
A study of rain water harvesting for sustainable water resource management in Nagaland, Northeast India – a review
Authors: Lamneithem Hangshing  , Dhanasingh Sivalinga Vijayan  , Arvindan Sivasuriyan
Published: June 2023

Water is universally perceived as one of the most valuable natural resources. Global warming, changing climatic conditions, and population growth have necessitated more effective planning and management of water resources. Water is critical not only for agriculture, but also for industries and daily household activities. The overall rainfall pattern has shifted dramatically over the last two decades. Individuals, communities, industries, and governments occasionally faced uncertainty due to the heavy reliance on rainfall. It affects the socioeconomic environment, consumption patterns/capacity, and job creation, among other things. Countries such as Israel have succeeded in making optimal use of their water resources. Water scarcity results in drought, while an excess of water results in flood-like conditions, resulting in human and economic losses. Due to imbalanced rainfall, conventional water sources such as wells, rivers, and reservoirs are insufficient to meet water demand. As the rainwater collection system investigates a new water source, it can be viewed as a tool for managing water resources effectively. It places a premium on water storage and utilisation in a systematic and scientific manner. The purpose of this study is to determine how rainwater harvesting can contribute to sustainable water resource management in Nagaland by meeting diverse requirements and overcoming water-related challenges.
Investigation of molecular variability in some Aegilops species using Start Codon Targeted Polymorphism (SCoT) and CAAT-Box Derived Polymorphism (CBDP) markers
Authors: Eslamzadeh-Hesari Mohammad , Omidi Mansoor , Rashidi Varahram , Etminan Alireza , Ahmadzadeh Alireza
Published: June 2023

Among wild relatives of wheat, Aegilops species are ideal genetic resources
for the discovery of new characteristics such as resistance to environmental
stresses and even grain quality for wheat improvement. Hence, knowledge of
the population structure and genetic diversity of this germplasm is very
important for their conservation and further utilization. In the present
study, 80 accessions of the Aegilops including Ae. tauschii, Ae. cylindrica
and Ae. triuncialis were investigated for genetic diversity using SCoT and
CBDP markers. Eight SCOT and twelve CBDP primers amplified a total of 84 and
94 fragments with a mean of 10.50 and 7.83 fragments per primer,
respectively. Resolving power (Rp) for SCoT and CBDP primers varied between
6.04 and 11.65, and 13.08 and 28.02, with the polymorphic information
content (PIC) from 0.40 to 0.49 and 0.35 to 0.48, respectively. The results
of analysis of molecular variance (AMOVA) indicated that the highest
proportion of genetic variance referred to between species. SCoT primers
indicated high values for all informativeness parameter (except resolving
power) than CBDP primers across all tested accessions. However, CBDP primers
indicated higher values of the genetic parameters than using SCoT primers.
As a result, the maximum values for genetic parameters such as number of
effective alleles (Ne), Nei?s gene diversity (H) and Shannon?s information
index (I) were detected in Ae. cylindrica and Ae. triuncialis using SCoT and
CBDP markers, respectively. Cluster analysis based on those molecular system
grouped all accessions into three main clusters. The grouping pattern
observed by CBDP primers indicated more clear phylogenetic relationship
among some Aegilops species, so that PCoA?s results confirmed the grouping
pattern. In conclusion, it was observed that SCoT and CBDP displayed good
efficiency in depicting polymorphism among the tested accessions, however,
CBDP markers provided a clear grouping pattern of evaluated accessions.
Hence, the use of CBDP markers in determining population structure and
estimating genetic diversity in other plant species is recommended.
Molecular characterization and phylogenetic analysis of novel Wx genes from Psathyrostachys juncea and Eremopyrum bonaepartis
Authors: Wu Lijuan , Yang Zaijun , Wang Junqiang , He Jundong , Jiang Jin , Fang Fang , Shen Shian , Hu Xinkun
Published: June 2023

The ratio of amylose/amylopectin can greatly influence the end-use quality of
wheat products, and amylose synthesis only needs the granule-bound starch
synthase I that is encoded by the Waxy (Wx) gene. Hence, the Wx allele
variability is a vital determinant of amylose synthesis. In this study, four
novel Wx genes were isolated from two diploid Triticeae species. Their
sequence variations were analyzed, which showed that the polymorphism among
the Wx-F1 alleles was low; only seven single nucleotide polymorphisms (SNPs)
and one amino acid (AA) residue change (Arg541 ? Cys) were detected in the
exon regions, and this change in Wx-F1b was predicted to have deleterious
effects on protein function. The two Wx-Ns1 alleles in this study were
different from two published alleles obtained using three overlapping primer
sets. The polymorphism among the four Wx-Ns1 alleles was high, and 37 SNPs
and ten AA residue changes were found, while all of those substitutions were
neutral. However, one substitution (Leu237 ? Pro) between Wx-H1 and Wx-Ns1
was predicted that would probably affect the protein function. Divergence
time analysis showed that Wx-Ns1a diverged from Wx-Ns1b about 1.06 MYAs.
Phylogenetic analysis indicated that Wx-F1 were more closely related to
Wx-O1 from Henrardia persica, Wx-R1 from Secale cereale ssp. cereale, and
Wx-Xe1 from Eremopyrum triticeum, while Wx-Ns1 were more closely related to
Wx-H1 from Hordeum vulgare ssp. vulgare and Wx-Hch1 from Hordeum chilense.
These genes may be important candidates for wheat quality improvement.
Genotypic differences for chlorophyll, ash and N contents and their relations with grain yield in Turkish bread wheat landraces
Authors: Kara Rukiye , Akkaya Aydın
Published: June 2023

The genetic differences in the landraces are very important for plant
breeding. The aim of this study was to determine the genetic differences for
chlorophyll, ash and N contents and their relations with grain yield in
Turkish bread wheat landraces. There were significant genetic differences
for grain yield (GY), ash content of flag leaf at anthesis (AFLAC), ash
content of spike at anthesis (ASAC), ash content of flag leaf at maturity
(MFLAC), grain ash content (GAC), chlorophyll content at anthesis (ACC),
chlorophyll content at early milk maturity (EMCC), chlorophyll content at
late milk maturity (LMCC), chlorophyll content at early dough maturity
(EDCC), N content of flag leaf at anthesis (FLN) and spike N contents (SN).
The grain yield was positively and significantly related with AFLAC, ASAC,
MFLAC and ACC, negatively and significantly related with GAC, EDCC and SN,
not significantly related with EMCC, LMLC and FLN.
Progress, adaptability and stability of soybean grain yield and grain quality in conventionally created elite lines
Authors: Matosa-Kocar Maja , Sudaric Aleksandra , Duvnjak Tomislav , Andrijanic Zoe , Markulj-Kulundzic Antonela
Published: June 2023

The objective of this study was to determine the progress in grain yield and
grain quality accomplished with conventional breeding methods, as well as to
identify stable, widely or specifically adapted genotypes under central
European growing conditions. Recently developed soybean elite lines of
maturity groups (MGs) 00, 0 and I were compared with commercial cultivars
(standards) in comparative field tests during three consecutive years
(2018-2020) in Osijek, Croatia. The ANOVA results showed significant
genotype, environment, and genotype-by-environment interaction effects.
There was a significant improvement in productivity and quality in
comparison to standards, while stability parameters for tested traits
indicated there are stable and mostly specifically adaptable elite lines.
Improvement of the domestic gene pool and high agronomic performances of
elite lines stable in most important economic traits will considerably
contribute to increasing and improving soybean production in central Europe.