bluuebunny/crossref_metadata_2025 huggingface dataset:
Reacciones de trifluorometilación catalizadas por metales de transición
Authors: Gómez Benítez Eduardo Valente
Published: January 2022

Las reacciones de trifluorometilación tienen gran importancia en la industria farmacéutica por las propiedades que confieren a los compuestos que presentan tal grupo funcional. Este tipo de reacciones están presentes en la elaboración de sintones o unidades estructurales claves para la producción de Aprepitant, Fluoxetina, Leflunomida y Dutasterida, teniendo gran impacto en la industria farmacéutica. Se resumen los diferentes reactivos empleados en la trifluorometilación remarcando la relevancia que tienen las reacciones catalizadas por metales de transición en la obtención de procesos más baratos y limpios.
"DEPRESSÃO UNIPOLAR: Alimentação associada a depressão."
Authors: SOUSA FRANCISCA OLIVEIRA DE
Published: January 2022

A depressão é afetada por diversos fatores genéticos, hormonais, imunológicos, bioquímicos e neurodegenerativos, esses fatores são modulados por nutrientes obtidos dos alimentos que afetam a taxa de prevalência dessas enfermidades. Apesar de que, a doença se caracteriza por mudanças no estilo de vida, incluindo os hábitos alimentares, tem sido estudada a relação da alimentação e dos nutrientes específicos como forma de prevenção dessa patologia. Diversos nutrientes estão diretamente envolvidos na fisiopatologia da depressão, como por exemplo: a vitamina D, o zinco, o triptofano, o magnésio, os ácidos graxos ômega-3 e 6 e as vitaminas B (B6, B9 e B12). Portanto, o objetivo geral deste trabalho é estudar a associação da Depressão com a Alimentação tendo como objetivos específicos: Descrever a influência da alimentação na prevenção da depressão; verificar quais nutrientes contribuem na patogênese e na melhora dessa patologia; identificar alimentos que podem aumentar os riscos de transtorno depressivos. O estudo consiste em uma revisão da literatura, realizada através de um levantamento bibliográfico em artigos científicos publicados nos períodos de 2010 a 2021. A pesquisa foi realizada nas bases de dados da PubMed, Scielo e em livros da área com os descritores: Depressão, alimentação relacionada a depressão, alimentos, nutrientes e micronutrientes. A alimentação tem papel fundamental na depressão pois uma dieta rica em Triptofano, Ômega 3, vitamina D, Complexo B (B6, B9, B12), Magnésio e Zinco é capaz de influenciam positivamente no quadro dessa doença. Desta feita conclui-se que a depressão é uma doença multifatorial que a cada dia está mais presente na sociedade e a alimentação é um dos fatores que predispõe o aparecimento dos sintomas, devido à falta ou excesso de micronutrientes, cabe ao profissional de nutrição realizar uma avaliação junto ao paciente de transtorno mental. A promoção de uma alimentação saudável com melhores fontes de nutrientes ou suplementos é imprescindível na prevenção e no auxílio da recuperação dessa doença. PALAVRAS-CHAVE: Alimentação, Depressão, Nutriente
Sintomas de depressão, risco nutricional e capacidade funcional em idosos longevos
Authors: De Jesus dos Santos Amanda , Fuga da Silva Daiane , Gatti Ana Lucia , Lima Adriana Machado Saldiba de , Aquino Rita de Cassia de
Published: January 2022

Objetivou-se avaliar a relação entre sintomas de depressão, risco nutricional e capacidade funcional com características sociais, econômicas, demográficas e de saúde, em idosos longevos. Trata-se de uma pesquisa transversal, realizada em quatro municípios do estado de São Paulo. A relação entre as variáveis foi obtida por meio da técnica de Análise de Correspondência Múltipla. Foram avaliados 103 idosos, a maioria do sexo feminino, com idade entre 80 e 90 anos e com até quatro anos de estudo. Os resultados evidenciam a correspondência entre a presença de sintomas de depressão, risco nutricional, comprometimento funcional, baixa escolaridade e inadequada autoavaliação de saúde. Nota-se, portanto, a necessidade de uma abordagem interdisciplinar, e o desenvolvimento de políticas públicas direcionadas aos muito idosos, oferecendo atenção necessária para a redução do risco de depressão, de desnutrição e na melhoria da funcionalidade dos idosos longevos, que levem a um impacto positivo em sua qualidade de vida.
Avaliação do Apego em Adultos: estudo de revisão integrativa de escalas
Authors: Tartaro Gustavo Kastien , Baptista Makilim Nunes
Published: January 2022

O presente estudo tem como objetivo apresentar uma revisão literatura sobre medidas de apego publicadas no período de 2014 à 2019. Foi realizado levantamento de informações relativas ao número de itens, fatores, forma de resposta, dados de confiabilidade, principais métodos de investigação da estrutura interna. As bases de dados utilizadas foram: BIREME, PubMed, PsycNET, ScienceDirect, Wiley Online Library, SAGE, Springer e Redalyc. Dos 1384 artigos foram analisados 10 que corresponderam aos critérios de inclusão e exclusão. Os fatores os instrumentos apresentaram variações de 1 a 5 fatores e diferentes métodos de análise. Uma lacuna importante encontrada, foi a ausência de um instrumento de apego brasileiro.
Representações Sociais sobre a atuação do psicólogo escolar e educacional
Authors: Carvalho Leilanir De Sousa , De Araújo Ludgleydson Fernandes , Negreiros Fauston
Published: January 2022

O artigo tem como objetivo investigar as Representações Sociais (RS) da prática do psicólogo escolar e educacional por parte de estudantes universitários de psicologia. A pesquisa foi realizada com 101 universitários do curso de psicologia de uma instituição pública, que estavam cursando ou já havia cursando a disciplina psicologia escolar. Os dados coletados, por meio da Técnica de Associação Livre de Palavras (TALP), foram analisados de acordo com os parâmetros recomendados pela Rede Semântica. As análises foram construídas tendo por base a referência teórica-metodológica da RS e teorias sobre a práticas na Educação. Os resultados apontaram como RS do psicólogo escolar e educacional indicando a importância desse profissional no âmbito escolar, atuando de forma crítica e articulada com a comunidade escolar, e a prática mediante a relevância da atuação.
OKUL ÖNCESİ ÖĞRETMENLERİNİN SİNEKTİK TEKNİĞİ HAKKINDAKİ GÖRÜŞLERİ
Authors: YILMAZ BOLAT Emine
Published: January 2022

Sinektik öğretim amacıyla kullanılan bir tekniktir, Bu çalışmada, okul öncesi öğretmenlerinin, sinektik hakkındaki bilgileri ve okul öncesi eğitimde sinektik tekniğinin kullanımı konusundaki görüşleriyle sinektik tekniği hakkındaki öz yeterlilik algıları ortaya koyulmuştur. Öğretim alanında da kullanılan bu teknik hakkında okul öncesi öğretmenlerinin görüşlerini ortaya koymayı amaçlayan bu araştırma nitel araştırma modelinde desenlenmiştir. Bu araştırma, durum tespiti yapmak amacıyla tarama modelinde desenlenmiş nitel bir araştırmadır. Veri toplamak için yarı yapılandırılmış görüşme tekniği kullanılmıştır. Bu görüşme formu uzman görüşleri doğrultusunda araştırmacılar tarafından hazırlanmıştır. Araştırma Mersin il merkezinde görevli 20 okul öncesi öğretmeni ile yürütülmüştür. Veriler araştırmacılar tarafından geliştirilen açık uçlu soru formu aracılığıyla toplanmıştır. Yarı yapılandırılmış görüşme formunda kişisel bilgilerin yanı sıra, sorunun amacına yönelik olarak öğretmenlerin sinektik tekniği hakkındaki bilgi düzeylerine, bu tekniği kullanımı konusundaki görüşlerine ve sinektik tekniği konusundaki yeterlilik algılarına ilişkin sorulara yer verilmiştir. Veriler betimsel analiz ile çözümlenmiştir. Araştırmada katılımcıların sinektik tekniğini genel olarak bildikleri ancak uygulamadıkları ve bu konuda kendilerini yeterli bulmadıkları sonucuna ulaşılmıştır. Katılımcıların 14’ü bu tekniği tanımlarken 6’sı hiç bilmediklerini ifade etmişlerdir. Öğretmenlerden sadece 2’si sinektik tekniğini uyguladıklarını, 9’unun ise bu tekniği hiç kullanmadıklarını belirtmişlerdir. Ayrıca sadece 4 öğretmen kendini bu konuda yeterli bulduğunu ifade ederken 16 katılımcı, kendini bu tekniğin uygulaması konusunda yeterli bulmadığını belirtmiştir.
P’olipunkciuri –d kartulshi da ughvlilebis morposint’aksuri modelebi /პოლიფუნქციური -დ- ქართულში და უღვლილების მორფოსინტაქსური მოდელები [Polyfunctional -d- in Georgian and Morphosyntactic Models of Conjugation]
Authors: Baramidze Tsira
Published: January 2022

We discuss the morphological and syntactic bases for polyfunctionality of marker -d- in the process of changing the model of Georgian verb conjugation, based on the premise that Georgian, like all Ibero-Caucasian languages, was the language of the class conjugation. The d- > *d- morphological marker is used in those languages where the grammatical class is a valid category and in those languages where the grammatical category of the class has already disappeared, the meaning of d and its use with a different function are frequent. There are few cases of expressing the valence of a subject with the suffix -d; for the most part, the direct object is conveyed by the suffixes -n / -d. Thus, in this new but infinite part of conjugation, the suffixes -n / -d convey not only S3 but also the valence of the subject if the verb is intransitive and the valence of the object if the verb is transitive. -d was also used as the passive voice marker. The -d- used in the marking of the passive voice is nothing but the reinterpretation of the archaic *d (grammatical class marker) in the new system, where it can only denote the valence of the subject. As for the active voice, the special marker of which does not exist in the verb, d- is considered to be a marker in active verbs, and the meaning of this term is not fully clear.
-d that occurs in the Georgian verb conjugation system is the reinterpretation of the archaic *d (the historical marker of the grammatical class). The principle of the economy of markers has proven to be particularly productive in the process of changing the conjugation models in the Georgian language.საკვანძო სიტყვები: ქართული ენა, პოლიფუნქციური -დ, უღვლილება, მორფოსინტაქსური მოდელი.Keywords: Georgian Language, polyfunctional -d, conjugation, morphosyntactic models
Zanuridan (megrul-lazuridan) shetvisebuli leksik’uri erteulebis ponet’ikur-ponologiuri da semant’ik’uri adap’t’aciisatvis svanurshi /ზანურიდან (მეგრულ-ლაზურიდან) შეთვისებული ლექსიკური ერთეულების ფონეტიკურ-ფონოლოგიური და სემანტიკური ადაპტაციისათვის სვანურში [Phonetic, Phonological and Semantic Adaptation of Zan (Megrelian-Laz) Vocabulary in Svan]
Authors: Saghliani Medea
Published: January 2022

In the present article, which offers the analysis of phonetic-phonological and semantic transformations of several lexical units assimilated from Zan (resp. Megrelian-Laz) into Svan dialect-sub-dialects in different epochs and in different ways, in the footsteps of our research, all the opinions related to each analytical lexical unit, which are expressed in the academic literature by Georgian or foreign linguists, are taken into account. Naturally, the paper also focuses on material that is lost in Zan itself, although it is preserved in Svan, mainly in the Lower Bal dialect, which indicates the ancient borrowing of this material and, at the same time, its archaism.The lexical units assimilated from Zan, as the observation of the material demonstrated, are attested in Svan both phonetically-semantically unchanged, as well as with different phonetic variants or semantic nuances (modified data). Some of the borrowed roots are “Svanized”, it means they contain morphological inventory typical of Svan: palatal, velar or labial umlaut, long vowel, anaptyctic element, etc. In addition, the following phonetic processes are quite tangible in one part of the lexical units borrowed from Zan: sound alternation, reduction processes in light and hard forms, loss of sounds, etc.In Svan, several such stems (resp. root, morpheme, affix) have been identified, which are either missing or manifested in other forms in Zan. Clearly, such forms, which were presumably preserved by Svan as relics, indicate their ancient borrowing. In our opinion, revealing any archaic form will allow Georgian or foreign comparativists to restore many archetypes. We believe, such research is very important and interesting for presenting a general picture of the development of Svan phonological and lexical systems.
საკვანძო სიტყვები: ქართველური (ზანურ-სვანური) ლექსიკა, ფონეტიკური
პროცესები სვანურში, სემანტიკური ცვლილებები.
Keywords: Kartvelian (Zan-Svan) vocabulary, Phonetic processes in Svan, Semantic
changes.
Questions of criminalistic characterization and criminalistic classification in the methodology of investigation of drug smuggling
Authors:   Caspian Public University, Nizamedinov R.А.
Published: January 2022

The article deals with the issues related to the study of the content of criminalistic characteristics and criminalistic classification in the methodology of investigation of drug smuggling. In the context of the economic crisis and the growing threats to the national security of the state in modern conditions, there is a need to find the most effective ways to improve investigative and judicial practice on a fundamental scientific basis. Generalization of theoretical provisions in the field of economic security and analysis of the dynamics of drug addiction problems as a global threat to the health of the country's population and national security. This circumstance requires a particularly balanced approach to the development of new and improvement of existing norms in the industry law.
About some issues of the work of the concerning commission
Authors:   Caspian Public University, Mustafanova E.N.
Published: January 2022

This article is devoted to the analysis of the effectiveness of the work of the conciliation commission in the consideration of an individual labor dispute. A brief analysis of this issue is given. Recommendations for improving the legal mechanism of this method of protecting labor rights and interests of employees are given.
Securing the performance of the loan obligation
Authors:   Caspian Public University, Sayatova M.N.
Published: January 2022

The article examines the legal nature of the institution of ensuring the fulfillment of obligations. An analysis of the methods of security known in civil law is carried out and an attempt is made to determine among them the optimal ones for use in the field of credit relations. At the same time, it is emphasized that the list of ways to ensure the fulfillment of obligations contained in the Civil Code of the Republic of Kazakhstan is open, allowing the subjects of civil law relations to independently develop the most convenient ways to secure obligations.
Features of providing electronic banking services under bank account and bank deposit agreements
Authors:   Caspian Public University, Anuarbekova K.A.
Published: January 2022

The article deals with the issues of concluding bank account and bank deposit agreements remotely, the mandatory conditions for such agreements, as well as the issues of providing electronic services in an online format. The analysis of the means of customer identification used by banks in the provision of electronic banking services is carried out. The concept of an electronic document in accordance with the banking legislation of the Republic of Kazakhstan is considered, and a proposal is put forward to improve the current version of the concept of an electronic document provided for by the legislation of the Republic of Kazakhstan on an electronic document and an electronic digital signature.
Using Co-Inquiry to Study Co-Inquiry: Community-University Perspectives on Research
Authors: Banks Sarah , Armstrong Andrea , Booth Mark , Brown Greg , Carter Kathleen , Clarkson Maurice , Corner Lynne , Genus Audley , Gilroy Rose , Henfrey Tom , Hudson Kate , Jenner Anna , Moss Robert , Roddy Dermot , Russell Andrew
Published: January 2022

In the context of a rapid development of interest in community-university research partnerships, this article argues for a greater focus on collaborative reflexivity to enhance learning from the research process and contribute toward developing sustainable and ethical research collaborations. Incorporating perspectives of community and university participants, the article offers a case study analysis of a UK-based co-inquiry action research group. This group not only studied examples of community-university research collaborations, but also reflected on its own workings as an example of collaborative research in action—scrutinizing relationships of power, responsibility, and boundaries in the group (collaborative reflexivity). This article argues that research projects might be designed with space designated for co-inquiry action research or similar inquiry groups. These co-inquiry groups would serve as replacements or supplements to more traditional steering or advisory groups.
DEALING WITH WEAR: CARE AND PALLIATIVE MECHANISMS FOR COMPASSION FATIGUE
Authors: Antonio  Dominguez
Published: January 2022

The Compassion Fatigue concept is common in the sci-entific literature of International Social Work, although surprisingly nonexistent in Spanish literature. Fatigue can be defined by compassion as a state of exhaustion and biological, psychological and relational dysfunction, the result of immediate or prolonged exposure to compassionate stress and as the final result of the progressive and cumulative process resulting from pro-longed, continuous and intense contact with clients or clients. patients, the use of oneself and exposure to stress.

 The maintenance of the wear can lead to severe pictures typical of secondary traumatization or the onset of Burned Professional Syndrome (Burnout). In any case, if a social work professional experiences this phenomenon, their ability to empathize, connect and help their clients is severely diminished. Paradoxically, compassion fatigue is, on the one hand, necessary and inevitable if good practice is developed; on the other, dangerous and disabling if it is not compensated by other mechanisms. Compassion fatigue can not be prevented but it can and must be palliated consciously. Increasing the ability to recognize and minimize the impact of attrition is a responsibility of the professional and the organization in which he works. Finally, the work raises what to do about this phenomenon and how to take care of yourself, professionally and institutionally.
Défis et potentiel du futur développement agricole en Jordanie: rôle de l'éducation et de l'entrepreneuriat
Authors: Abdullah Bataineh  , Francesco Zecca
Published: January 2022

Le document examine l'état du développement de l'agriculture en Jordanie, les défis actuels et le potentiel de développement futur. Le but de l'étude est de découvrir le rôle de l'éducation et de l'esprit d'entreprise dans la promotion du développement agricole en Jordanie à travers: l'introduction de nouvelles technologies dans le secteur; appliquer une perspective de marketing moderne et mondiale et l'autonomisation de l'entrepreneuriat des jeunes. Cette étude est basée sur une approche théorique basée sur la recherche secondaire, et la recherche primaire comprend deux enquêtes ont été menées à cette étude. Comme diverses études, cette étude a confirmé que la rareté de l'eau est le principal défi du développement agricole en Jordanie et que le secteur est moins développé que d'autres secteurs du pays. Néanmoins, cette étude a ajouté que la faible participation de l'entrepreneuriat des jeunes dans le secteur n'est pas seulement due à la pénurie financière et aux connaissances insuffisantes des jeunes, mais aussi à leur faible attitude à l'égard du travail dans l'agriculture. Par conséquent, il est suggéré qu'il est nécessaire de modifier considérablement le paradigme du système éducatif pour répondre aux besoins du marché. Utiliser également le rôle de la R&D pour améliorer la gestion des ressources en eau et mettre l'accent sur le dessalement et la réutilisation des eaux usées, et changer l'attitude des jeunes à l'égard du travail dans l'agriculture. Ajoutez à ce qui précède qu'il est nécessaire de fournir plus de soutien financier et technique pour attirer et aider les jeunes entrepreneurs à investir dans le secteur. En conséquence, une occasion de relever les défis actuels et de favoriser le développement futur se présentera.
Performance Assessment and Implementation of the Triple Bottom Line on Industrial Companies Listed on the Indonesia Stock Exchange
Authors: Kustinah Siti
Published: January 2022

This study aimed to determine the performance appraisal and implementation of the triple bottom line in industrial companies listed on IDX. This research uses descriptive quantitative research. The annual report is analyzed using the content analysis method, which collects data using observation and analysis techniques on messages from documents to produce an objective and systematic description. The type of data used in this study is secondary cross-sectional data collected through documentation techniques. Based on the non-parametric test that has been carried out, it can be concluded that the disclosure of triple bottom line reporting in Indonesia is still very minimal. It is suspected that the company did not use the annual report to communicate between the company and its stakeholders. It is possible that the company only uses the yearly report as information for shareholders and potential investors.
The challenges of Rural Students in Vietnam towards higher education
Authors: Lo Van Pang
Published: January 2022

This study aims to explore the challenges and difficulties that rural students experience when they transition to Higher Education in Vietnam to pursue their higher studies. This study was carried out at a local University in Vietnam. It is a qualitative research study, and data were collected through semi-structured interviews with 10 participants. The participants were all first-year students, including males and females. The interviews involved answering semi-structured questions. Multiple interviews were carried out with each participant. The study discovered that rural students experience many difficulties at university in relation to their relationships with teachers and peers, getting support, overcoming prejudice, online learning, and economic hardship.
Trimodal therapy vs. radical cystectomy for muscle-invasive bladder cancer: A Canadian cost-effectiveness analysis
Authors: Kool Ronald , Yanev Ivan , Hijal Tarek , Vanhuyse Marie , L. Cury Fabio , Souhami Luis , Kassouf Wassim , Dragomir Alice
Published: January 2022

Introduction: Trimodal therapy (TMT) is a suitable alternative to neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for patients with muscle-invasive bladder cancer (MIBC). In this study, we conducted a cost-effectiveness evaluation of RC±NAC vs. TMT for MIBC in the universal and publicly funded Canadian healthcare system.
Methods: We developed a Markov model with Monte-Carlo microsimulations. Rates and probabilities of transitioning within different health states (e.g., cure, locoregional recurrence, distant metastasis, death) were input in the model after a scoped literature review. Two main scenarios were considered: 1) academic center; and 2) populational-level. Results were reported in life-years gained (LYG), quality-adjusted life years (QALY), and incremental cost-effectiveness ratios (ICER). A sensitivity analysis was performed.
Results: A total of 20 000 patients were simulated. For the academic center model, TMT was associated with increased effectiveness (both in LYG and QALY) at a higher cost compared to RC±NAC, at five and 10 years. This resulted in an ICER of $19 746/QALY per patient undergoing the TMT strategy at 10 years of followup. For the populational-level model, RC±NAC was associated with higher effectiveness at 10 years, with an ICER of $3319/QALY per patient. This study was limited by heterogeneity within the studies used to build the model.
Conclusions: In this study, TMT performed in academic centers was cost-effective compared to RC±NAC, with higher effectiveness at a higher cost. On the other hand, RC±NAC was considered cost-effective compared to TMT at the populational-level. Further studies are needed to confirm these results.
Explainable artificial intelligence to predict the risk of side-specific extraprostatic extension in pre-prostatectomy patients
Authors: Kwong Jethro C.C. , Khondker Adree , Tran Christopher , Evans Emily , Cozma Adrian I. , Javidan Ashkan , Ali Amna , Jamal Munir , Short Thomas , Papanikolaou Frank , Srigley John R. , Fine Benjamin , Feifer Andrew
Published: January 2022

Introduction: We aimed to develop an explainable machine learning (ML) model to predict side-specific extraprostatic extension (ssEPE) to identify patients who can safely undergo nerve-sparing radical prostatectomy using preoperative clinicopathological variables.
Methods: A retrospective sample of clinicopathological data from 900 prostatic lobes at our institution was used as the training cohort. Primary outcome was the presence of ssEPE. The baseline model for comparison had the highest performance out of current biopsy-derived predictive models for ssEPE. A separate logistic regression (LR) model was built using the same variables as the ML model. All models were externally validated using a testing cohort of 122 lobes from another institution. Models were assessed by area under receiver operating characteristic (AUROC), precision-recall (AUPRC), calibration, and decision curve analysis. Model predictions were explained using Shapley Additive exPlanations. This tool was deployed as a publicly available web application.
Results: Incidence of ssEPE in the training and testing cohorts were 30.7 and 41.8%, respectively. The ML model achieved AUROC 0.81 (LR 0.78, baseline 0.74) and AUPRC 0.69 (LR 0.64, baseline 0.59) on the training cohort. On the testing cohort, the ML model achieved AUROC 0.81 (LR 0.76, baseline 0.75) and AUPRC 0.78 (LR 0.75, baseline 0.70). The ML model was explainable, well-calibrated, and achieved the highest net benefit for clinically relevant cutoffs of 10–30%.
Conclusions: We developed a user-friendly application that enables physicians without prior ML experience to assess ssEPE risk and understand factors driving these predictions to aid surgical planning and patient counselling (www.ssepe.ml).
Напрями розвитку пірингового кредитування в Україні
Authors: Жаворонок А. В.
Published: January 2022

У статті досліджено напрями розвитку пірингового кредитування в Україні. Визначено, що даний вид кредитування тільки-но починає свій розвиток в Україні. В даний час працює тільки дві онлайн платформи пірингового кредитування. Зосереджено увагу на тому, що основною перевагою Р2Р кредитування є доступність, адже зараз кожен має доступ до мережу Інтернет. Визначено основні пропозиції для збільшення темпів розвиткуР2Р кредитування: створення стабільної та зваженої нормативно-правової бази; створення української асоціації онлайн платформ р2р кредитування; створення єдиного сайту, де буде акумульована вся інформація про онлайн платформи пірингового кредитування. Наголошено на тому, що слід обов’язково усвідомлювати притаманні перешкоди, перед впровадженням будь-яких нововведень. В будь-якому випадку при створенні чогось нового для платформи найбільшою перешкодою стане потреба у виділенні значної суми додаткових коштів. Щоб покращити становище потрібно створити якомога кращі умови для притоку користувачів, які через час принесуть прибуток власникам платформи.
Фінансове забезпечення інноваційної діяльності в системі підвищення конкурентоспроможності переробних підприємств АПК
Authors: Лагодієнко Н. В. , Шаповалова І. О. , Рибалко С. В.
Published: January 2022

У статті охарактеризовано роль інновацій в підвищенні конкурентоспроможності підприємств переробної промисловості АПК в Україні. Визначено, що реалізація ключових напрямів інноваційної діяльності підприємств переробної промисловості АПК потребує створення ефективної системи фінансового забезпечення та залучення значних обсягів фінансових ресурсів як із внутрішніх, так і зовнішніх джерел. Розглянуто динаміку  обсягів та структури фінансування інноваційної діяльності переробних підприємств АПК. Проаналізовано переваги та обмеження основних джерел фінансового забезпечення інноваційної діяльності в контексті забезпечення конкурентних переваг підприємств. Обґрунтовано можливості розширення можливостей фінансування інновацій через активізацію використання нетрадиційних джерел фінансових ресурсів. З метою забезпечення конкурентоспроможності переробних підприємств АПК обґрунтовано необхідність дотримання ними основних принципів формування системи фінансування інноваційної діяльності: пріоритетності, плановості, безперервності, множинності, результативності, адаптивності та цільового використання ресурсів.
RATIONALITY OF ANTIBIOTICS USE WITH QUANTITATIVE AND QUALITATIVE METHODS AT HOSPITAL IN INDONESIA
Authors: Diah Suminar Fadhila
Published: January 2022

Infection is one of the biggest causes of death in Indonesia which can be influenced by the appropriate use of antibiotics. Irrational use of antibiotics can cause bacteria to become resistant to antibiotics so that the effectiveness of the drug decreases or even disappears. This study aims to evaluate the use of antibiotics given to inpatients at a private hospital in Indonesia both quantitatively and qualitatively in the period July to December 2021. This study is an observational study with retrospective data collection where qualitative analysis using the Gyssens Method and quantitative analysis uses the DDD method. The results of the qualitative analysis showed that from 30 cases observed, there were 9 cases (30%) irrational prescriptions, namely 1 case in category V, 4 cases in category IVA, 2 cases in category IIIB and 2 cases in category IIA. The results of the quantitative analysis showed that the antibiotics with the highest DDD/100 patient days in the period July to December 2021 were Ceftriaxone with a successive value of 39.15; 39.81; 36.22; 55.65; 41,48 and 49, 42 while antibiotics with the lowest DDD/100 patient-days values in the period July to December obtained different results. Based on research results, there are irrational antibiotic prescriptions and Ceftriaxone became the most commonly prescribed antibiotic.
DEVELOPMENT OF AUGMENTED REALITY (AR) INTERACTIVE STORYBOOK “BERSIH DIRI BERSAMA MARE” BASED ON ANDROID TO STIMULATE MOTOR DEVELOPMENT OF CHILDREN AGED 4-5 YEARS
Authors: Putri Eka Mawardani Irmala , Sutama I Wayan , Astuti Wuri
Published: January 2022

Media storybooks based on Augmented Reality can be used by teachers to stimulate motor development about personal hygiene in children aged 4-5 years. The purpose of this research is to produce Augmented Reality interactive storybook media products that are validly tested by media and material experts with categories, effective, efficient and interesting in their use. The type of research used in this research is the type of Research & Development (R and D) research. The assessment criteria are aspects of efficiency, effectiveness and attractiveness. The instrument of quantitative data analysis technique was obtained from the validity of media experts and material experts. The results of accumulated validity from several experts yield a percentage of 97.75% which means it is very feasible to use. The trial used small groups and large group tests with the criteria for assessing effectiveness, efficiency and attractiveness with the results of 87.7%. The accumulation of data from the results of expert validation and group trials was 91.5%, which means that the media is feasible to use. Quantitative data was obtained from the results of interviews with kindergartens in Blitar. The researcher found that the interactive augmented reality storybook about self-cleaning with mare had three eligibility criteria, namely being effective, efficient and attractive to stimulate motor development about personal hygiene in children aged 4-5 years.
MEMAHAMI MAKNA DEMOKRASI DALAM PENDIDIKAN DEMOKRASI
Authors: Hutabarat Dany Try Hutama , Sinta Nuria , Dwiva Nur Aulia , Raihandi Muhammad Abiyyu , Ardiansyah Ari , Febrian Sazri , Akbar Ghani
Published: January 2022

The purpose of this study is to identify and comprehend the meaning of democracy through democratic education. This research method is qualitative approach based on a literature review. Democracy is a way of life that must develop and flourish in citizens, both those in positions of authority (state administration) and those who are not in positions of authority (ordinary citizens). This democratic way of life will result in a democratic culture. To support the form of government and political system, a positive attitude toward life and a democratic culture are required. Democracy education essentially establishes a democratic culture that will eventually become the democratic structure.
Pengaruh Penerapan model pembelajaran kooperatif tipe think pair share pada pembelajaran matematika di Madrasah
Authors: Ningsih Yudia Mahyu , Sucipto Lalu , Fitriyah Any Tsalasatul
Published: January 2022

Penelitian ini bertujuan untuk mengetahui ada tidaknya pengaruh penerapan model pembelajaran kooperatif tipe think pair share (TPS) terhadap motivasi belajar matematika siswa kelas VIII MTs Darunnajah Al-Falah Telagawaru. Populasi dalam penelitian ini adalah siswa kelas VIII MTs Darunnajah Al-Falah Telagawaru. Teknik pengambilan sampel yaitu menggunakan teknik sampling jenuh dengan jumlah masing-masing 24 siswa yang terdiri dari 2 kelas dengan total keseluruhan 48 orang. Dalam penelitian ini peneliti memilih kelas VIII B sebagai kelas eksperimen dan kelas VIII A sebagai kelas kontrol. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian eksperimen dengan pendekatan kuantitatif. Metode pengumpulan data dilakukan dengan menggunakan metode angket, metode observasi, metode wawancara dan metode dokumentasi. Teknik analisis data menggunakan uji-t yang sebelumnya dilakukan uji prasyarat yaitu uji normalitas dan uji homogenitas. Hasil perhitungan uji-t diperoleh nilai t hitung= 4,239 dan ttabel = 2,069 untuk taraf signifikan 5% dengan df = (n–1) = (24–1)=23. Sehingga berdasarkan kriteria pengujian hipotesis dengan menggunakan t-test yaitu jika thitung > ttabel (4,239 > 2,069) maka hipotesis alternatif (Ha yang diterima), karena berdasarkan perhitungan ternyata hasil dari thitung = 4,239 lebih besar dari t tabel = 2.069 maka Ha diterima atau penolakan H0, dengan demikian dapat dikatakan bahwa terdapat perbedaan secara signifikan
Hubungan Kedekatan Keluarga dengan Konsep Diri Remaja Putri di Panti Asuhan Al Islam, Sleman, Yogyakarta
Authors: Salim Nasiatul Aisyah , Antok Nurwidi Antara
Published: January 2022

Adolescene is a critical period of development. Adolescents face a period of searching for answers to questions about themselves. So that adolescence is an important period in the formation of self concept. Parents are the earliest social contact experienced by a person and the most powerful in the formation of self concept. However, some teenagers are faced with the choice of having to separate from their families and live in orphanages. Several psychological problems are experienced by adolescents who live in orphanages so that it will affect the process of forming adolescent self concepts. This study aims to determine the relationship between the closeness of parents with the self concept of young women with the type of research that is observational analytic with cross sectional study design. The number of samples as many as 18 people with a sampling technique that is total sampling. Sampling using a questionnaire and data analysis using the chi square test. The result of this study indicate that self concept and family closeness in the good category is 61,1 %. However, the results of data analysis showed that there was no relationship between family closeness and self concept (0,24). It is hoped that the young women of the orphanage can socialize and easily get along with the environment in order to further increase their self confidence so that their self concept will be better.
Tinjauan Lama Waktu Penyediaan Rekam Medis Rawat Jalan Di Rumah Sakit Anna Medika Bekasi
Authors: Febriarini Winda , Puteri Fannya  , Nanda Aula Rumana  , Noor Yulia
Published: January 2022

In the provision of medical record files in hospitals, it is one indicator of patient satisfaction whose time has been determined in accordance with the hospital's minimum service standards, the standard for the time of providing medical record documents for outpatient services is less than or equal to 10 minutes.  10 minutes), while the time for providing inpatient medical record documents is less than or equal to 15 minutes (  15 minutes). The purpose of the study was to determine the length of time for providing outpatient medical records at Anna Medika Hospital Bekasi. The research method uses a descriptive method with a quantitative approach, the population of outpatient medical record files visiting the hospital, the sample studied is 106 files, through observation, interviews and time measurement records in the timely provision of medical records so that researchers get research results. The results of the study found that 59 (55.66%) medical records were provided on time and 47 (44.34%) medical records were not provided on time. Factors causing the length of time of provision > 10 minutes are errors in storing medical records, full storage shelves, lack of competence of medical record officers. Suggestions can improve the quality of service and the speed of time for providing medical records and holding standard operating procedures (spo) regarding the provision of medical records.
Bioremediation of textile dye effluents using indigenous earthworm Lampito mauritii (Kinberg)
Authors:   Department of Zoology, Annamalai University, Annamalai Nagar, Tamil Nadu, India, B Subash , P Vijayan ,   Department of Zoology, Annamalai University, Annamalai Nagar, Tamil Nadu, India, S Senthilmurugan ,   Department of Zoology, Annamalai University, Annamalai Nagar, Tamil Nadu, India, K Ramarajan ,   Department of Microbiology, Bharathidasan University, Thiruchirappalli, Tamil Nadu, India
Published: January 2022

The present study is intended to assess and monitor the Bioremediation of textile dye effluent using Lampito mauritii earthworm. The study focus on the bioremediation of surface water of SIPCOT dye industry Cuddalore district over a period of one year and has revealed variations among the different parameters at different study sites. For the analysis of surface water three sampling sites were selected for the study. In the area, from SIPCOT dye industry to Cuddalore district the parameters concentration was decreased and it is useful for drinking purpose. Heavy metals such as copper and zinc are essential elements for metabolic activities however they show toxic effects when exposed to higher levels whereas lead, mercury, cadmium and are not essential for metabolism which they exhibit toxic properties. The heavy metals of surface water in the study area are in the order of Zn > Cu > Pb > Cd > Hg (mg/L) respectively. Mercury, cadmium were noticed in least level in the non-industrial area whereas industrial area concentration of metals were slightly increased than the prescribed limits. The examination of water samples for bacteriological parameter includes MPN index, total heterotrophic bacterial colony count, morphological and biochemical characteristics. MPN is a suitable and widely used method to determine the microbial quality of water. Due to heavy rain the microbial load was increased during monsoon season. Based on morphology and biochemical characteristics, identify the species of the organism namely Escherichia coli, Vibrio cholerae, Salmonella typhi, Klebsiella pneumoniae, Enterobacter aerogenes and Pseudomonas aeruginosa. Based on motility, shape, size and structure, the organism was identified and based on IMVIC tests of biochemical reaction with production of acid and gas the organism was identified.
Heavy metal pollution in soil and Water around landfill dumpsite
Authors:   Department of Microbiology, PKN College of Arts and Science, Tamil Nadu, India, Anjanapriya Subramanian , Sureka Manickam ,   Department of Zoology, Sree Sevugan Annamalai College, Devakotti, Tamil Nadu, India, Sasirekha Nambirajan
Published: January 2022

Anthropogenic activity enhances the heavy metal contamination in surrounding environment. This research was designed to measure the metal pollution level from soil and ground water system around land fill dumpsite. The levels of pollution measured from 0 distances to 1200m distance of landfill. The overall study indicated that concentration of heavy metals Arsenic(As), Mercury(Hg), Lead(Pb), Cadmium(Cd), Chromium(Cr), Copper(Cu), Nickel(Ni) and Zinc(Zn) were witnessed in very near to dumpsite also the concentration was decreased when distance increased. The levels of As, Hg, Pb, Cd, Cr, Cu, Ni and Zn in soil were observed every 300m distance (90.75, 90, 77.3, 98.5, 92.3, 58, 95.9 and 94%) respectively. The above level was compared to 1200m distance; the concentration was gradually reduced to (36.8, 0, 51.7, 51.8, 50.4, 56, 51.3 and 46%) separately. Also the concentration of heavy metals in ground water samples at 300 m distance were (100, 96, 90.2, 93.91, 92, 95.5, 100, and 97.3%) the levels reduced to (24.2, 10.3, 30.7, 29.6, 52.5, 49.6, 21.1&57.5%) at 1200m distance. This indicated that the nearest area soil and ground water were highly polluted; however the heavy metals concentration was reduced gradually at far distance. To reduce th toxic compounds from the waste, create awareness for the people to limit the waste from every house. Sanitary landfilling and composting is an excellent and ecofriendly manner of waste mangement
Prevalence of Coccidia in sheep at the Bauchi Abattoir, Inkil, Bauchi state
Authors:   Department of Zoology, Branch Entomology, Abubakar Tafawa Balewa University Bauchi, Nigeria, Sule Ibrahim Friday , Kingsley Deda Gayi ,   Department of Ecology, Branch Entomology, Abubakar Tafawa Balewa University Bauchi, Nigeria, Adamu Ngeri Mark
Published: January 2022

Coccidiosis is a disease that destroys the intestinal mucosa which is caused by the protozoa parasites of the genus Eimera or Isospora species. The symptoms include diarrhoea, fever, weight loss, emaciation and consequently, death. Many infections are subclinical (that is, not severe enough to cause readily observable symptoms). Coccidiosis is an economically important disease of cattle, sheep, goats, pigs, poultry and also rabbits, in which the liver and intestine are affected. In dogs, cats, and horses, coccidiosis is less often diagnosed but can result in clinical illness.
CALCULATION OF THE PARAMETERS OF STOCHASTIC NEUTRON KINETICS IN ZERO POWER NUCLEAR REACTORS
Authors: Zemskov E , Melnikov K , Tormyshev I
Published: January 2022

The majority of neutron-physical problems of nuclear power plants design can be solved on the basis of various approximations to the Boltzmann transport equation in terms of the averaged characteristics of the reactor: the effective multiplication factor, neutron flux, average neutron lifetime, etc. However, the neutron chain reaction itself is always stochastic. There are situations in which the stochastic nature of the chain reaction cannot be ignored. This is the so-called “blind” start-up problem with a weak external neutron source, the work of physical assemblies of “zero” power, the analysis of the reactivity noise of such assemblies, etc. Despite the well-developed theoretical basis for the stochastic description of the behavior of neutrons in a nuclear reactor, there are still not enough calculation algorithms and programs for stochastic kinetics analysis. The paper presents two computational algorithms for point reactor model, which are developed on the basis of the theory of Markov branching random processes. The first one is based on the balance equation for the probabilities of death and birth of prompt and delayed neutrons in a reactor, the second one is based on calculating the first and second moments of neutron number distributions and using the assumption that these distributions can be approximated by gamma distributions with sufficient accuracy. On the basis of these algorithms, programs have been created that allow one to calculate various scenarios for introducing reactivity and an external source into the system. The calculation of pulsed experiments on prompt and delayed neutrons to determine the waiting time of the threshold neutron pulse at the Godiva II installation showed a qualitative agreement of the results for both the two computational algorithms and the experimental data.
VVER REACTOR SAFETY ASSESSMENT IN RIA TYPE ACCIDENTS DURING POWER GRID REGULATING REGIMES
Authors: Uvakin M , Makhin I , Sotskov E
Published: January 2022

Work deals with RIA accidents safety assessment problem for VVER reactor, which is operating in normalized primary power grid frequency regulating regimes (FR). Frequency regulating regimes leads to turbine load variations and following continuously changing of main reactor facility parameters by feedbacks and regulators actions. Dynamic reactor conditions can be taking into account in safety assessment calculations and may needs in specialized methodical approach. Considered dynamical method application performs by mathematical model for initial event and FR combination detection which is worst for safety. Model includes the full scope of calculation and theoretical reactor dynamics analysis during FR transient processes. Model approbation is given by some safety analysis examples such as RIA type accidents: control rod ejection, uncontrollable rod group withdrawal and control rod drop with space power distribution perturbation.
THE ANALYSIS OF NUCLEAR SAFETY AT TREATMENT OF MBIR REACTOR FUEL
Authors: Fraaz E , Malkov A
Published: January 2022

The main results of neutron and physical calculations for the unirradiated and fulfilled fuel storages of the MBIR reactor, transport processing equipment and radiation protective cameras are adduced in this work. The analysis was made in full accordance with requirements of the state normative documents for nuclear safety of research nuclear facilities. The results of effective neutron reproduction coefficient calculations received with use of the MCU-RFFI/A program were used for the analysis. According to the results of neutron and physical calculations, the NSM mass, enrichment, a step and geometry of placement of products in a binding reactor facility rooms restrictions were set, norms of loading at which nuclear safety at the unirradiated and fulfilled storage of MBIR reactor fuel, transport and technological operations are provided both in regular conditions, and in the considered emergencies were defined. The dependence of effective coefficient of neutron reproduction changes at unauthorized water ingress into points of "dry" storage and the equipment from water density was calculated, the maximum values were defined. The extreme values of effective neutron reproduction coefficient at violation of placement geometry of the nuclear sharing materials owing to external influences and human errors were also defined. The quantity and geometry restrictions of products arrangement with the nuclear sharing materials for all radiation protective cameras on the basis of settlement researches were set.