bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effects of the Exercise of Kindergarten Teachers' Rights and the Recognition of Children's Rights on Teacher-Child Interactions
Authors:   Gyeongin National University of Education, Kim Da-Hye , Jang Young-Sook
Published: October 2024

This study investigated the effects of exercising kindergarten teachers’ rights and recognizing children’s rights on teacher–child interactions. To this end, an online survey was conducted on 320 teachers from public and private kindergartens in Seoul, Gyeonggi, and Incheon. Pearson correlation and stepwise multiple regression analyses were conducted to analyze the collected data using SPSS 29.0. The following results were obtained: First, exercising kindergarten teachers’ rights was somewhat higher than the intermediate level, and recognizing children’s rights and teacher–child interactions were high. Second, significant positive correlations were found among exercising kindergarten teachers’ rights, recognizing children’s rights, and teacher–child interactions. Third, the freedom of expression and right to participation, which is the sub-factor of recognizing children’s rights, had the most significant effect on teacher–child interactions. Following this, the right to survival and care, right to appropriate developmental support, and teacher’s right to status and property also had sequentially significant effects. These findings suggest that various strategies to enhance teachers’ rights and awareness of children’s rights should be developed to improve the quality of teacher–child interactions.
Factores de riesgo psicosocial y obesidad
Authors: Cardona Herrera Consuelo , Osorio Valencia Francisco Javier , Herrera M. Julián Alberto
Published: October 2024

Se realizó un estudio descriptivo en 165 pacientes del Centro de Atenci6n Básica (CAB) «La Selva» del Instituto de Seguros Sociales, Cali, Colombia, con el fin de determinar la prevalencia de la obesidad y establecer su asociación con factores de riesgo psicosocial. Se evaluó la presencia de obesidad mediante el índice de masa corporal (IMC); igualmente se evaluó la función familiar, el soporte de amigos, los niveles de ansiedad y depresión, hábitos y estilo de vida. Se encontró una prevalencia de obesidad de 34.5%. Cuando se evaluó el estado civil en la población estudiada se encontró una asociación significativa de la obesidad con la condición de no soltero(p<0,0002 OR=6,12 IC95% 2.11-19.03). E/IMC aumentó con la edad con índice de correlación lineal de 0.42 (p<0.005). En el análisis multivariado el sexo masculino, el consumo de licor se correlacionó significativamente (OR= 9.33, IC 95% 1.48-58.6, p <0.02), con un lMC mayor de 30. No hubo asociación estadísticamente significativa entre obesidad, ansiedad, depresión o disfunción familiar.
Tricobezoar como causa de obstrucción intestinal alta
Authors: Padilla-Ramírez Harold
Published: October 2024

Los tricobezoares son cuerpos extraños insólitos compuestos por pelo y alimentos que se impactan y forman un molde dentro del estómago o intestino, y pueden causar una obstrucción intestinal. De esta entidad hay escasos informes en la literatura. Se presenta el caso de una niña de 12 años, con diagnóstico de tricobezoar, manejada quirúrgicamente, con buena evolución. Se revisa esta rara enfermedad y se dan pautas para su diagnóstico y tratamiento.
Una aproximación al estudio de la epidemiología de los trastornos del aprendizaje
Authors: Carrasquilla José Gabriel , Henao Olga Lucía
Published: October 2024

Es tiempo de comenzar diseños de estudios de los tratarnos de aprendizaje que permitan cumplir con los objetivos que se propone la epidemiología y que han de aportar mayores conocimientos sobre tales disfunciones y los factores que se relacionan con ellas. Sin duda alguna, el método epidemiológico ofrece un camino muy atractivo para lograrlo.
Epidemiología de la preeclampsia
Authors: Herrera M. Julián A
Published: October 2024

La preeclampsia es la mayor causa de mortalidad materna, de parto prematuro, de retardo en el crecimiento intrauterino y de mortalidad perinatal. La causa exacta que la produce es desconocida; sin embargo, se sabe de varios factores asociados con la epidemiología, la inmunogenética y la bioquímica de la enfermedad. El reconocimiento preciso de estos factores de riesgo en el control prenatal, permitirá identificar de una manera más sensible a las embarazadas con mayor riesgo de desarrollar la preeclampsia, lo cual es importante para obtener un mayor impacto preventivo en el cuidado ambulatorio prenatal. En el presente artículo se revisan los diversos factores que se asocian con la epidemiología de lapreeclampsia y también los diferentes métodos preventivos que se informan en la literatura médica.
Enfoque del paciente reumático
Authors: Pérez Starusta
Published: October 2024

Estas guías para diagnósticos de las artritis,  deben servir sólo como lo que son;  no son infalibles y no reemplazan el estudio teórico y el conocimiento directo de los pacientes que se le presentan al médico en sus años de estudio o en la práctica activa de la profesi´ón.
Efecto de la relación pulpa: agua, °brix y temperatura sobre características fisicoquímicas, microbiológicas y sensoriales de bebida fermentada de Passiflora edulis y Ananas comosus
Authors: Jimenez Victor , Juarez Kevis , Sosa José
Published: October 2024

La investigación tuvo como objetivo evaluar el efecto de la relación pulpa: agua, corrección de °Brix y temperatura de inicio de fermentación sobre las características fisicoquímicas, microbiológicas y sensoriales de una bebida fermentada a partir de Passiflora edulis Sims y Ananas comosus L. Merril. Se desarrollaron ocho tratamientos utilizando un diseño Completamente al Azar (DCA) con arreglo factorial para la evaluación de los tres factores (relación pulpa: agua, corrección de grados brix y temperatura de inicio de fermentación) y dos niveles de cada uno: (1:1, 1:2), (25, 30 °Brix) y (30, 35 °C) respectivamente. Para las características sensoriales se aplicó un Diseño en Bloques Aleatorizado (DBCA). Los datos fueron analizados con Microsoft Excel 2016 y IBM SPSS versión 20. La formulación más aceptada fue (T8) por 30 catadores quienes evaluaron las características sensoriales en una escala hedónica de 9 puntos. Finalmente, la bebida fermentada T8 obtuvo un pH de 3.26, acidez de 0.72, 17 °Brix y un grado alcohólico de 12.20. El T8 presentó recuento de mohos y levaduras menor a 1.0 UFC/ml, coliformes totales menor a 3.0 NMP/ml y aerobios mesófilos menor a 1.0 UFC/ml, encontrándose dentro del rango establecido por la RM N° 591- 2008/MINSA.
Estudio de mercado para el lanzamiento de un nuevo formato de café orgánico en la región Amazonas
Authors: Maicelo-Vilca Anita , Guevara-Guevara Ronal , Bustos-Chavez Meliza del Pilar , Maicelo-Vilca José , Rituay-Trujillo Pablo Alfredo , Campos-Trigoso Jonathan Alberto
Published: October 2024

El café orgánico peruano es altamente valorado por su calidad excepcional, aroma agradable y sabor intenso, posicionándose entre los mejores del mundo. Actualmente, los consumidores buscan métodos de preparación rápidos e innovadores que ofrezcan una experiencia satisfactoria y promuevan la lealtad. Este estudio tuvo como objetivo realizar un análisis de mercado para el lanzamiento de un nuevo formato de café orgánico en la región Amazonas, Perú. Se encuestó a 620 personas con afinidad o interés en el consumo de café. Los resultados muestran que el 84.85% de los encuestados estarían dispuestos a consumir café en un nuevo formato. El atributo más valorado fue la calidad del producto (77.27%), mientras que las bodegas fueron el punto de venta preferido por su rápida disponibilidad (53.03%). La presentación en cajas de 20 filtrantes fue la opción más popular (57.58%). Se concluye que existe una oportunidad significativa para el desarrollo e introducción de este nuevo producto en el mercado.
Efecto del simbiótico multicepa sobre el comportamiento productivo de pollos de carne
Authors: Castillon–Poma David , Crispin–Perez Astrid V. , Reza–Poma Erni
Published: October 2024

El objetivo de esta investigación fue evaluar el efecto de la inclusión de diferentes niveles del simbiótico multicepa POULTRYSTAR®SOL sobre el consumo alimenticio, ganancia de peso, conversión alimenticia y retribución económica en pollos Cobb 500, llevado a cabo en la Unidad Experimental de Avicultura de la Universidad Nacional Agraria La Molina. Se emplearon 160 pollos BB machos, distribuidos en cuatro tratamientos y cuatro repeticiones; los tratamientos fueron diferentes niveles de simbiótico multicepa POULTRYSTAR®SOL (T0: dieta basal sin simbiótico, T1: dieta basal con 0.05 % de simbiótico, T2: dieta basal con 0.08 % de simbiótico y T3: dieta basal con 0.10 % de simbiótico). Para ganancia de peso T0 no mostro diferencias significativas con T1, con 2 853.750 g y 2 929.725 g respectivamente, pero sí con T2 (2 947.65 g) y T3 (2 937.40 g). Hubo menor consumo de alimento en T3 (5 230.325 g) y el mayor consumo de alimento en T0 (5 324.025 g); la conversión alimenticia fue menor en T3 (1.775). Se tuvo mayor retribución económica en los pollos alimentados con distintos niveles del simbiótico multicepa frente al tratamiento testigo; siendo el tratamiento con simbiótico multicepa la mejor alternativa.
Çağın Yükselen Liderliği: Hizmetkâr Liderlik Literatürünün Bibliyometrik Analizi
Authors: Demirler Serap
Published: October 2024

Araştırmanın temel amacı, alanın genel bir resmini ortaya koymaktır. Çalışmada, hizmetkâr liderlik literatürünün yıllar içerisinde nasıl bir seyir izlediği ve bunun literatüre nicelik ve nitelik bakımından nasıl yansıdığı bibliyometrik yöntem kullanılarak araştırılmıştır. Bibliyometrik yöntemin bilimsel alan haritalama ve ortak kelime analizi teknikleriyle alanın genel özellikleri incelenmiş ve kavramsal yapısı ortaya konulmuştur. Araştırma bulgularında, hizmetkâr liderlik literatürünün nicelik ve nitelik açısından hızla geliştiği yorumunu yapmak mümkündür. Konuyla ilgili yapılan yayın sayısının artışına göre alanı iki dönemde incelemenin mümkün olduğu görülmüştür. Söz konusu dönemler arasında çeşitli performans göstergeleri ve kavramsal yapı bakımından farklılıklar olduğu sonucuna ulaşılmıştır. Hizmetkâr liderlik konusunda alana katkı sunan ülkeler bazında son dönemde Asya bölgesi öne çıkmaktadır. Bunun yanında, ikinci dönemde özellikle Covid-19 süreci sonrasında, kavramsal yapı bakımından çalışanların bilişsel ve duygusal sağlıklarını dengelemeye yönelik değişkenlere yoğunlaşıldığı görülmektedir.
Yogurt in the prevention of diabetes mellitus
Authors: Varon Joseph
Published: October 2024

Yogurt, a popular fermented dairy product, is lauded for its nutritional benefits and role in promoting gut health. Recent studies have highlighted its potential in preventing chronic diseases, including type 2 diabetes mellitus (T2DM). This abstract delves into the mechanisms through which yogurt exerts its beneficial effects and explores how its regular consumption may contribute to diabetes prevention. Yogurt is rich in essential nutrients such as calcium, vitamin D, protein, and probiotics. The probiotics, particularly strains of Lactobacillus and Bifidobacterium, play a crucial role in maintaining gut microbiota balance. These live bacteria contribute to improved digestion and enhance immune function, pivotal in managing and preventing metabolic disorders like T2DM.
Perioperative nutrition in bariatric surgery
Authors: Sutanto Luciana Budiati
Published: October 2024

Many patients think very simply about bariatric surgery, namely that after surgery the body soon becomes slim. In reality, carrying out bariatric surgery still follows the medical surgical procedure with all its complications, so the doctor must carry it out medically well and it would be ideal to follow standard guidelines.
Nutritional therapy in a severely injured multiple traumas patients with hypovolemic shock, acute kidney injury, and hypoalbuminemia
Authors: Wibowo Maria Vickyliana , Budiman Maria Ingrid
Published: October 2024

Severely injured multiple trauma patients that undergoing surgery generally have a high risk of malnutrition. Surgery can cause a series of reactions including releases of stress hormone and inflammatory mediators that is called Systemic Inflammatory Response Syndrome. The syndrome causes hypermetabolism due to catabolism of glycogen, fat, and protein to enhance the recovery of healing and immune responses and maintain peripheral protein mass. Therefore, nutritional support is essential for the optimal recovery of these patients.
The effect of bitter melon (M.charantia) consumption on fasting blood sugar in patients with type II diabetes mellitus: A systematic review
Authors: Sitepu Regina , Tobing Christin
Published: October 2024

Morbidity and mortality from diabetes is a serious alarm to carry out an adequate prevention and management. Bitter melon (M. Charantia) is widely available and often consumed in Indonesia. It has been traditionally used in various cultures particularly in managing diabetes. This effect is believed to be due to compounds found in bitter melon that mimic insulin's action, helping to improve glucose uptake and utilization by cells.
Positive effects of probiotics against alzheimer’s disease
Authors: Tjung Vivienne , Azzahrah Aisyah , Sari Amelya Agusthina Ayu
Published: October 2024

Alzheimer's disease (AD) is a neurodegenerative disease related to elderly with subtle onset and progressive impairment of behavior and cognitive functions that is projected to increase without medical breakthroughs. Recent medication effectiveness is limited, only symptomatic treatment is available, none are curative, and variably palliative. Studies suggest an association between gut health and Alzheimer's progression through the “microbiome-gut-brain axis”. A scoping review was conducted to further explore the positive effects of probiotics on AD, highlighting potential of enhancing cognitive function, mitigating inflammation, and improving lipid profiles.
Correlation between total animal and plant protein intake, with body mass index in tuberculosis patients during the intensive phase in Dili and Oecusse
Authors: Marques lafo Merita , Chandra Dian Novita , Nurwidya Fariz , Sequiera Ercia Maria da Conceicao
Published: October 2024

Tuberculosis causes decreased appetite and hypermetabolism, disrupting protein breakdown and synthesis, leading to malnutrition. Proteins, as the primary source of amino acids, support immune cells and help prevent malnutrition and susceptibility to other infections. The intensive phase of tuberculosis therapy is crucial for enhancing immune defense, reducing the bacterial load, and decreasing energy expenditure, thereby increasing body weight.
Components driving the detection of stunting cases among Posyandu cadres using precede model
Authors: Batubara Astriana Marta , Februhartanty Judhiastuty , Iswarawanti Dwi Nastiti
Published: October 2024

Cadres of Posyandu are frequently considered the frontline of community health programs, including in detecting and managing stunting. However, there are limited descriptions of the relevant factors driving their roles in stunting detection, particularly based on the PRECEDE model. The purpose of this study was to describe the multifactorial components driving cadres in finding stunting cases in Sumedang District, West Java.
Consequências da privação de sono para a saúde mental
Authors: Mesquita Matheus Lopes Bitar , Silva Bianca Rafaela Farias da , Pinto Fernando Freitas da Silva , Paraense Jorge Luis Moscoso , Tavares Ingrid Neves , Silva Monique Gisela Oliveira e , Barros Larissa Cristina Machado de
Published: October 2024

Objetivo: Analisar os impactos da privação de sono sobre o surgimento de transtornos mentais e sobre o agravamento dos casos prevalentes. Métodos: Realizou-se uma revisão integrativa da literatura para responder à questão: “Quais as consequências da privação de sono para a saúde mental?” por meio de pesquisa nas bases de dados on-line MEDLINE, LILACS, SCIELO, Scopus e Webscience vinculadas à PUBMED e à BVS. Foi realizado o filtro dos estudos e das teses em inglês e em português publicados de 2018 a 2023, por meio de descritores como “Sono”, “Privação do Sono”, “Qualidade do Sono”, “Saúde Mental”, “Transtornos Mentais”, “Depressão”, “Ansiedade” e “Condições Sociais”, com o uso dos operadores booleanos “AND” e “OR”. Resultados: 20 artigos obedeceram aos critérios de inclusão e não foram excluídos, dentre os quais todos explicitaram que a privação do sono influencia negativamente na saúde mental. Considerações finais: A partir das informações reunidas, foi possível delimitar e facilitar a identificação dos perfis mais propensos à relação maléfica entre a falta de sono e os danos psicológicos, estimulando a elaboração de novos estudos que aprofundem nos mecanismos biológicos sobre o tema.
Obstáculos para o diagnóstico e tratamento do transtorno do espectro autista
Authors: Sousa Ana Clara Santos de , Amorim Natan Kauan Campos , Saraiva Juracy Morais Lima , Serra Mariana Barreto
Published: October 2024

Objective: To understand the obstacles that reduce accessibility to the diagnosis and treatment of autism spectrum disorder (ASD). Literature review: ASD is a disorder characterized by difficulties in social interaction, impairments in communication and restricted patterns of behavior. Its diagnosis is clinical, based on behavioral observations and the patient's history and on criteria defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM – 5). Treatment includes pharmacological and behavioral approaches. However, the difficulties and challenges found in the literature include the symptomatological heterogeneity of ASD, the need for training health professionals and a more accurate assessment through a multidisciplinary team. Late diagnosis or its absence can lead to unfavorable outcomes in adult life, such as: anxiety, depression, and difficulty in interpersonal relationships. Recent studies include the use of specific biomarkers and innovative therapies that are not yet accessible. Final considerations: Early diagnosis and appropriate treatment are ideal for improving the quality of life of individuals with ASD. The importance of the doctor and new studies to improve therapeutic choice in ASD is also highlighted.
Hanseníase em indígenas do estado do Tocantins: perfil de casos e análise de tendência, 2001-2022
Authors: Almeida Maria Clara Conti , Martins Nicoly Pommer , Monteiro Geisa Guimarães , Monteiro Jakeline Heville Duarte Pereira , Monteiro Lorena Dias , Guimarães Liana Barcelar Evangelista , Pereira Thayza Miranda
Published: October 2024

Objetivo: Descrever os padrões epidemiológicos da hanseníase nos povos indígenas do estado do Tocantins, Brasil, analisando os perfis dos casos e as tendências da doença de 2001 a 2022. Métodos: Estudo quantitativo com dados secundários de hanseníase do Datasus, empregando análise de regressão joinpoint para identificar mudanças significativas nas tendências de detecção de casos novos ao longo do tempo. Resultados: Foram diagnosticados 180 casos novos de hanseníase em indígenas. Houve predominância do sexo masculino (56,1%), multibacilares (63,9%) e forma clínica dimorfa (56,1%). O percentual de casos com grau 1 de incapacidade física no diagnóstico foi de 22,8% e grau 2 de 10,6%. Predominou na região de saúde do Médio Norte Araguaia (47,8%). A análise de regressão joinpoint mostrou variação significativa nas tendências de detecção, com redução na população geral de -3,3% ao ano de 2001 a 2015, seguida por aumento e subsequente queda significativa. Entre indígenas, houve inicialmente um aumento e depois redução significativa na detecção de novos casos. Conclusão: Há necessidade de estratégias de controle da doença adaptadas às peculiaridades culturais e socioeconômicas dos povos indígenas do Tocantins. A evidência de transmissão ativa e diagnóstico tardio reforça a importância de intervenções focadas e culturalmente sensíveis.
Fatores associados ao nascimento de filhos de migrantes internacionais no município de Caxias do Sul
Authors: Kohlrausch Larissa Fernanda , Dal Molin Rossano Sartori
Published: October 2024

Objetivo: Investigar os fatores epidemiológicos associados ao nascimento de filhos de migrantes internacionais nascidos no município de Caxias do Sul. Métodos: Caracterizou-se por uma pesquisa quantitativa, exploratória e transversal, seguindo as recomendações STROBE. Foram analisados dados secundários, provenientes do SINASC, disponibilizados pela Secretaria Municipal de Saúde de Caxias do Sul. Resultados: Foram 873 nascimentos analisados, entre 2013 e 2023.  49% dos nascimentos foram de filhos de haitianas, com aumento progressivo nos anos de 2019 e 2020, seguido de filhos de venezuelanas, nos anos de 2022 e 2023. O perfil das mães foi de raça/cor preta (51,9%), idade de 26 a 35 anos (55,55%), solteira (46,39%), ensino médio (52,55%) e ausência de gestações anteriores (34,69%). O pré-natal tem como média de 9 consultas e início do entre o 1º e 3º mês (72,32%). 62% dos partos ocorreram via SUS e cerca de 89,15%, a termo. Apgar de 1º minuto de 78,81% maior que 7 e, de 5º minuto, 95,08% maior de 7. Peso ao nascer de 60,85% entre 3000g e 3999g. Conclusão: Notou-se o aumento expressivo de nascimentos de filhos de migrantes no município de Caxias do Sul nos últimos anos, destacando as naturalidades haitiana e venezuelana.
Tuberculose pulmonar: uma análise da incidência e da cobertura da atenção primária de saúde na mesorregião do Marajó
Authors: Abreu Theikson Ferreira de , Santos Victor Gabriel Oliveira , Pinheiro Maria da Conceição Nascimento
Published: October 2024

Objetivo: Descrever a incidência da tuberculose pulmonar e a cobertura da atenção primária de saúde na mesorregião do Marajó, no período de 2011 a 2021. Métodos: Utilizaram-se dados de domínio público disponíveis no Sistema de Informação de Agravos de Notificação (SINAN) e no Departamento de Informática do Sistema Único de Saúde (DATASUS), referentes aos casos novos de tuberculose pulmonar de cada município que compõe cada microrregião. O número de estratégias de saúde da família (ESF) foi obtido do site E-Gestor do Ministério da Saúde, e as estimativas populacionais do Instituto Brasileiro de Geografia e Estatística (IBGE, 2021). Resultados: Taxas variáveis de incidência e cobertura foram registradas entre as cidades das microrregiões do Marajó. Soure apresentou a maior taxa de incidência (8,57); Melgaço teve o pior IDH (0,418) e a menor taxa de cobertura de ACS (55,2%). Na microrregião de Furos de Breves estão localizadas as maiores taxas da doença. Conclusão: Ao analisar o perfil da tuberculose pulmonar na população do Marajó, observou-se que o acesso limitado aos serviços de saúde e o baixo IDH corroboraram para a incidência da tuberculose pulmonar na mesorregião do Marajó.
Níveis de estresse e estratégias de coping em estudantes de enfermagem no contexto pandêmico
Authors: Vieira Márcia Daiane Ferreira da Silva , Costa Carla Caroline Vieira da , Gouveia Márcia Teles de Oliveira , Martins Ozirina Maria da Costa , Carvalho Ana Raquel Batista de , Costa Maria Carolina da Silva , Sousa Marcele Avelino , Lira Ivana Mayra da Silva , Soares Yndiara Kassia da Cunha
Published: October 2024

Objetivo: Avaliar os níveis de estresse e as estratégias de coping utilizadas por estudantes de enfermagem no contexto pandêmico. Métodos: Estudo descritivo, realizado com 144 acadêmicos de Enfermagem cujos os dados foram obtidos por meio de um questionário para identificar o perfil sociodemográfico, instrumento de Avaliação do Estresse em Estudantes de Enfermagem (AEEE) e pela escala Coping Orientation to Problems Experienced Brief (Brief COPE). Resultados: A maioria dos estudantes eram do sexo feminino, possuíam idade entre 20 e 24 anos, solteiros, não possuíam filhos, possuíam vínculo empregatício, porém não trabalhavam na área da saúde. Na aplicação do instrumento AEEE, 40,28% apresentaram alto nível de estresse, onde “Atividades teóricas” foi o preditor de maior índice. Na análise das estratégias de coping, “Planejamento” foi a estratégia mais utilizada, seguido da Religião” e da “Reinterpretação positiva”. Este estudo contribui para uma atenção ao uso de metodologias que adaptam ao perfil do aluno no contexto em que se insere, recomenda-se ainda que as instituições do ensino superior acompanhem o estado de saúde mental dos seus estudantes. Conclusão: Os acadêmicos de enfermagem possuem um alto nível de estresse, relacionado principalmente a atividades teóricas. Ademais, durante a pandemia tiveram como principal estratégia de coping o planejamento.
Образование как социальная проблема современного мира
Authors: Мапельман В.М.
Published: October 2024

В статье речь идет об основных принципах образования, широко реализуемых в настоящее время в мире существенных особенностях политики общества в отношении просвещения, обучения и образования элементах образовательной стратегии, способных представлять собой угрозу для культуры социума последствиями своей реализации.

The material deals with the basic principles of education, widely implemented in the world today on the essential features of public policy regarding schooling, training and education about the elements of educational strategy that can constitute a threat to the culture of society by the consequences of its implementation.
Прогнозирование национальной экономики с учетом возможного воздействия негативных факторов
Authors: Маршова Т.Н.
Published: October 2024

В статье предложены подходы к построению многоуровневой многофункциональной системы прогнозирования экономики, способной учитывать влияние негативных факторов различного характера. Показано, что для разработки и совершенствования методологии и методов экстремального прогнозирования необходима существенная корректировка статистического обеспечения прогнозных расчетов, значительные изменения на всех этапах составления прогноза. Рассмотрены основные принципы разработки соответствующего модельного инструментария.

Approaches to the construction of a multilevel multifunctional forecasting system of the economy, capable of taking into account the influence of negative factors of different nature, are proposed. It is shown that in order to develop and improve the methodology and methods of extreme forecasting, there is a need for a significant correction of statistical support for forecast calculations, significant changes at the stage of scenario scenario development. The main principles of development of the corresponding model tools are considered.
Многомерный статистический анализ развития инфраструктуры информатизации и коммуникаций в регионах РФ
Authors: Платонова И.В.
Published: October 2024

В данной статье проанализировано распределение объемов инвестиций по виду деятельности в области информатизации и связи. Определены значения среднегодовых приростов основных показателей, характеризующих динамику внедрения информационных и коммуникационных технологий в организации субъектов РФ. С помощью многомерных статистических методов классификации и снижения размерности получена кластерная модель регионов РФ по уровню развития информационных и коммуникационных технологий.

This article analyzes the distribution of investment by type of activity in the field of informatization and communications. The values of the average annual growth of the main indicators characterizing the dynamics of the implementation of information and communication technologies in the organization of the constituent entities of the Russian Federation are determined. Using multidimensional statistical methods for classifying and reducing dimensionality, a cluster model of the regions of the Russian Federation was obtained in terms of the level of development of information and communication technologies.
Задачи Банка России по регулированию рынка услуг ломбардов
Authors: Андрющенко А.М. , Андрющенко Г.И.
Published: October 2024

В статье анализируется стратегия государственного регулятора на микрофинансовом рынке с целью уточнения его воздействия на рынок услуг ломбардов и необходимость определения оптимальной регуляторной нагрузки. Кроме того, авторами рассматриваются факторы, определяющие формирование институциональной структуры рынка услуг ломбардов и необходимость внедрения саморегулирования в этом сегменте.

In article the strategy of the state regulator in the microfinancial market for the purpose of specification of its impact on the market of services of pawnshops and need of definition of optimum regulatory loading is analyzed. Besides, in article the factors defining formation of institutional structure of the market of services of pawnshops and need of introduction of self-regulation in the market of services of pawnshops are considered by authors.
Когнитивная оценка организационной культуры колледжа как элемента инновационной архитоники вуза
Authors: Кухаренко О.Г. , Починок П.А.
Published: October 2024

Цель исследования заключается в том, чтобы на основе применения методики оценки организационной культуры OCAI, основанной на теоретической модели рамочная конструкция конкурирующих ценностей К. Камерона и Р. Куинна, исследовать специфику инновационной составляющей организационной культуры колледжа как уровневого элемента инновационной архитоники вуза в его взаимосвязи с конкурентной рыночной средой.

The research objective is in that on the basis of application of a technique of assessment of organizational culture of OCAI founded on the theoretical model frame design of the competing values of K. Cameron and R. Kuinn to investigate specifics of an innovative component of organizational culture of college as a-level element innovative very tonics of higher education institution in its interrelation with the competitive market environment.
The logging equipment effect on the dynamics of natural reforestation of after cutting mixed coniferous-deciduous stand in the middle taiga
Authors:   Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Kutyavin I. N. , Manov A. V. ,   Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Starcev V. V. ,   Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Dymov A. A. ,   Institute of Biology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences
Published: October 2024

The work presents the results of experimental studies on assessment of preliminary and subsequent reforestation depending on the disturbance of the soil cover by logging equipment. The initial survey of the reforestation in the clearing showed the uneven settlement of the territory by woody plants in most parts and individual technological elements. According to morphological characteristics and a set of soil genetic horizons, the soil can be classified as typical Albic Retisols, which develop on loamy soil-forming rocks in well-drained landscapes. We found that the soil of the skidding trail is morphologically close to the original soil. The drag soils have undergone both morphological and chemical changes. The key difference is the change in the composition of the organic horizon following the arrival of a large amount of felling residues and changes in the composition of the ground cover plants. The morphometric parameters of the trees in the mixed stand and undergrowth are of high lability. The stand was dominated by small trees and small undergrowth. The stand and undergrowth are characterized as “healthy”. Relatively good uniformity of its settlement by woody plants was revealed only on portages in ruts with a predominant regeneration of small-leaved species. When the trails are heavily littered, there is no appearance of woody plants. There is no regeneration in the reclaimed felling areas in the first and second years. There is no resumption in sections with aligned tracks in the first and second year.
Effect of cationic, anionic and non-ionic surfactants on soil oligochaetes Eisenia fetida andrey (Bouche, 1972)
Authors:   Irkutsk State University, Stom D. I. ,   Baikal Museum SB RAS,   Irkutsk National Research Technical University, Dolgikh M. M. ,   Irkutsk State University,   Baikal Museum SB RAS, Titov I. N. ,   Vladimir State University named after Alexander and Nikolay Stoletovs, Dambaeva G. V. ,   Irkutsk State University, Zhdanova G. O. ,   Irkutsk State University, Stom A. D. ,   Irkutsk State University, Boguspaev K.-K. K.-K. ,   Al-Farabi Kazakh National University, Maksimova S. L. ,   State Scientific and Production Association “Scientific and Practical Center of the National Academy of Sciences of Belarus for Bioresources”, Kupchinsky A. B. ,   Baikal Museum SB RAS
Published: October 2024

Results of studying the main types of surfactants effect on earthworms Eisenia fetida andrey (Bouche, 1972) are presented. The worms were tested for survival and preference-avoidance behavioral reactions. Earthworms avoided sodium dodecyl sulfate (SDS) at 0.02 g/kg and above, cetyltrimethylammonium bromide – at 0.1 g/kg and above, and polysorbate 80 – at 30 mL/kg and above. The 100% mortality of earthworms occurred at 0.001, 0.01 and 0.02 g/kg of SDS on day 30, at 1 g/kg – on day 25, and at 1 g/kg – on day 2 of the experiment. Сetyltrimethylammonium bromide at 0.001 and 0.01 g/kg caused the 100% mortality of worms on day 30; at 0.1 g/kg – on day 25; at 0.5 g/kg – on day 5; and at 1.0 g/kg already on day 2 of the experiment. The 100% mortality of worms occurred at 0.1, 1 and 10 mL/kg of polysorbate 80 on day 30 of incubation; at 20 or 30 mL/kg – on day 20; at 50 mL/kg – on day 10 of experience. The following toxicity series (both in terms of g/L and in terms of g/mol) of the tested surfactants for earthworms was constructed on the basis of the results obtained (increasing toxicity): polysorbate 80 (non-ionic surfactant) < cetrimonium bromide (cationic surfactant) < sodium dodecyl sulfate (anion-active surfactant).
Soil algae and cyanoprokaryota of steppe communities of the Baikal basin
Authors:   Siberian Institute of Plant Physiology and Biochemistry Siberian Branch of the Russian Academy of Sciences, Egorova I. N. , Tupikova G. S. ,   Siberian Institute of Plant Physiology and Biochemistry Siberian Branch of the Russian Academy of Sciences, Shergina O. V. ,   Siberian Institute of Plant Physiology and Biochemistry Siberian Branch of the Russian Academy of Sciences, Kazanovsky S. G. ,   Siberian Institute of Plant Physiology and Biochemistry Siberian Branch of the Russian Academy of Sciences
Published: October 2024

The article presents the results of studies of herbaceous plant communities in the Baikal basin, with the significant participation of the diazotrophic cyanoprokaryota Nostoc commune. The territory of the investigation is located at the foot of the Primorskiy range. There are developed mountain, typical steppe, and meadow communities on chestnut soils. A high content of carbonates was found in the soils, and the pH of the upper horizons varied from slightly acidic to alkaline. The composition of algae and cyanoprokaryota species living in and on soils has been revealed. In total, in steppe and meadow communities we identified 71 species from five divisions: Cyanoprokaryota – 27, Bacillariophyta – 4, Ochrophyta – 3, Chlorophyta – 34, and Charophyta – 3. 58 species have been found in steppe communities, 40 in meadow. A predominance of cyanoprokaryota and green algae was noted. The composition of the studied phototrophic species in steppe communities differed significantly from that of the meadow. In steppe communities Nostoc commune formed macroscopic colonies, and its biomass production was low (about 2 g/m2) comparable to that of a number of Asia arid territories. The N. commune biomass formation was higher on the mountain slope and at its foot, where higher density of soil composition, lower field humidity, as well as an increased content of calcium, magnesium, and sodium was found in soils. The N. commune biomass was reduced in the site at a distance from the mountain slope where the content of the above elements was lower. The regular sampling of macrocolonies had a negative impact on their renewal.
Individual and geographic variability of Picea obovata cones in the Russian part of its area in relation to the seeds quantity in them
Authors:   Institute for the Development of the North of the Tyumen Scientific Center, Siberian Branch of the Russian Academy of Sciences, Popov P. P. , Kazantseva M. N. ,   Institute for the Development of the North of the Tyumen Scientific Center, Siberian Branch of the Russian Academy of Sciences, Arefyev S. P. ,   Institute for the Development of the North of the Tyumen Scientific Center, Siberian Branch of the Russian Academy of Sciences
Published: October 2024

The cone length of Picea obovata Ledeb. is closely related to the seeds quantity that causes the importance of full-scale study of this indicator. Studies were carried out in the entire Russian part of the P. obovata range from Murmansk region to Transbaikalia and Yakutia. It was found that geographical variability of cone length is relatively small (44–77 mm) and significantly inferior to individual variability (45–110 mm). The coefficient of a variation is 10 and 14%, respectively. We found that in the total population of Picea abies (L.) H. Karst. and P. obovata determined by their strong introgressive hybridization, cones of P. obovata is the category small and average. It is reasonable to distinguish an additional category of very small cones. The established categories of cones are characterized by the following length: very small 50 (54 mm and less), small 60 (55–64 mm) and medium 70 (65 mm and more). The approximate number of full seeds in them at good yields is 76 (less in extreme conditions of the Far North), 78–92 and 94–108 pieces, respectively. These figures are important for assessing the processes of spruce forest regeneration. Geographical distribution of average cone length in the studied territory it is not clearly expressed. The smallest cones are characteristic of spruce populations along Arctic Circle and in the Polar Regions, while in populations of the southern part of the range they are much larger. The majority of the Russian populations of P. obovata (about 2/3) have cones 65–70 mm long. The content of full seeds in cones is rather small.
Climatic changes in annual river runoff of the Northern Okhotsk Sea region
Authors:   North-East Interdisciplinary Scientific Research Institute n.a. N. A. Shilo, Far East Branch, Russian Academy of Sciences, Glotov V. E. , Ushakov M. V. ,   North-East Interdisciplinary Scientific Research Institute n.a. N. A. Shilo, Far East Branch, Russian Academy of Sciences
Published: October 2024

The aim of this study was to assess the climatic changes in the annual river runoff of the Northern Okhotsk Sea region within the Magadan region. In the present work the analyzed series end with data for 2019. Observation series of river runoff at eight hydrological stations were used in this work. By the method of hydrological analogy, these series were brought to a multiyear period by restoring year-on-year values. Thus, the series of annual runoff for 1958–2019 were analyzed. The research method was the analysis of runoff time series for the presence of homogeneity in the mean (Student’s criterion), as well as spectral analysis. Comparison of mean long-term values of runoff layers for two periods (1958–2000 and 2001–2019) showed that the “norm” increased by 5–37%. It should be noted that these changes are not random according to the Student’s criterion with significance level of 5%. The presence of a trend in long-term water availability fluctuations is also evidenced by the time course of the dynamic mean annual runoff. Analysis of the runoff series, mean annual air temperature and total annual precipitation made it possible to conclude that annual runoff increase is caused by climatic changes, mainly by an increase in precipitation. It is possible that runoff increase is also due to the thawing of ice in the permafrost strata. But you should pay attention to the fact that with climate warming, moisture losses for evapotranspiration increase, primarily due to the growth of trees and shrubs. Moreover, this effect is more noticeable in large catchments. A 6-year cyclicity was revealed in the long-term fluctuations of annual runoff. These fluctuations are most likely a non-stationary complex Markov process. The results of this work will be useful for hydrological calculations, long-term and ultra-long-term runoff forecasts, and studying the river – sea ecosystems. Further hydrological studies should be carried out with the obligatory study of evapotranspiration in various landscape conditions.
Effect of hydroxyapatite size on properties of PBS-DLS/HAp composites obtained by twin-screw extrusion and injection moulding techniques
Authors: Kryszak Bartłomiej , Zarei Moein , Biernat Monika , Szterner Piotr , Pagacz Joanna , Tymowicz-Grzyb Paulina , Antosik Agnieszka , Gąsiński Arkadiusz , Szustakiewicz Konrad , El Fray Mirosława
Published: October 2024

The aim of this work is to develop new polymer-ceramic composites based on poly(butylene succinate-dilinoleic succinate) (PBS-DLS) and hydroxyapatites (HAp) of different sizes. Irregularly shaped nano-hydroxyapatite (nHAp) and whisker-shaped micro-hydroxyapatite (μHAp) were used as fillers. For each of the hydroxyapatites, composites with copolymer:filler weight ratios of 9:1 and 8:2 were prepared by co-rotating twin-screw extrusion combined with injection moulding techniques. The investigations carried out allowed the characterisation of the specific behaviour of both fillers during processing, such as the tendency of nanoparticles to agglomerate or the breaking of whisker microparticles leading to a significant change in their aspect ratio (from about 4 to less than 3). A comprehensive characterisation of the produced materials was carried out and a comparison was made of the effect of filler particle size on the physicochemical and mechanical properties of the composites. A series of mechanical tests were carried out, such as dynamic thermo-mechanical analysis, quasi-static tensile test, quasi-static flexural test, impact strength and Brinell hardness, showing the reinforcing effect of the fillers used, with a predominance of whiskered micro-hydroxyapatite. The developed materials also showed good processability, thermal stability, bioactivity and biocompatibility towards the mouse fibroblast L929 cell line. The results presented in this work certainly provide useful information for the design and fabrication of effective polymer-ceramic biocomposites for bone tissue engineering applications.
Area-Selective Atomic/Molecular Layer Deposition of Photoluminescent Europium-Organic Thin Films for Graphene-Based Heterostructures
Authors: Emelianov Aleksei V. , Mentel Kamila K. , Ghazy Amr , Wang Yu-Han , Johansson Andreas , Karppinen Maarit , Pettersson Mika
Published: October 2024

Developing area-selective atomic and molecular layer deposition (ALD/MLD) on 2D structures is crucial for optoelectronic and sensor applications yet remains challenging due to surface inertness. Here, we investigated the area-selective ALD/MLD of luminescent lanthanide-organic materials on graphene. To overcome the inherent chemical inertness of 2D materials, we utilized direct femtosecond laser two-photon oxidation to activate predefined regions on single-layer graphene, enabling area-selective deposition of europium-organic thin films. By optimizing the deposition parameters and carefully choosing a transfer polymer, we achieved over 90% selectivity and high film homogeneity in the activated areas. When excited with a green laser, the resulting films exhibited high photoluminescence emission at 612 nm and weaker emission bands at 579, 592, and 652 nm. In addition, graphene/Eu-organic thin films demonstrated green emission at ≈566 nm. The presence of graphene also shortened the photoluminescence lifetime due to quenching. Moreover, the Eu-organic layer reduced the work function of the oxidized graphene, indicating a strong electronic interaction in the graphene/Eu-organic heterostructures. This method enables the precise patterning of complex structures with submicron resolution, with potential for integration into multifunctional graphene-based optoelectronic and sensor systems on a single chip.
Mechanism of a Novel Metal-Free Carbonic Anhydrase
Authors: Yadav Shalini , Kalita Surajit , Dubey Kshatresh
Published: October 2024

The recently discovered metal-free carbonic anhydrase (CA) enzyme may have a significant impact on the global carbon dioxide (CO2) cycle, as it can irreversibly perform the CO2 hydration reaction. In this study, we investigate several key aspects of metal-free CA, including the identification of the catalytic site, determination of the CO2 binding site, and the mechanism of catalysis. This is achieved through the use of classical molecular dynamics (MD) simulations, quantum chemical density functional theory (DFT), and hybrid quantum mechanics/molecular mechanics (QM/MM) calculations. Our study indicates that the experimental structure based on X-ray crystallography, which shows the ‘bicarbonate (HCO3−) product’ trapped in the hydrophilic region of the metal-free CA, might not accurately depict the actual enzyme-substrate picture. Instead, the simulation reveals that the CO2 prefers the hydrophobic zone, which serves as the primary catalytic site. It also highlights the strategic role of a gatekeeper residue (Phe504), which assists in regulating the transportation of CO2 by tilting its aromatic plane. Additionally, the hybrid QM/MM calculations establish that CO2 hydration is catalyzed within the hydrophobic zone by a deprotonated tyrosine with the help of an organized water chain.
Hypoxia-Responsive Polymersomes for Stemness Reduction in Patient-Derived Solid Tumor Spheroids
Authors: Edvall Connor , Kale Narendra , Tani Sakurako , Ambhore Shubhashri , Hossain Rayat , Ozoude Chukwuebuka , Van Horsen Karl , Mohammad jiyan , Tuvin Daniel , Kalathingal Santo , Loganathan Jagadish , Choi Yongki , Sathish Venkatachalem , Brown James , Mallik Sanku
Published: October 2024

Aggressive solid tumors are associated with rapid growth, early hypoxia, the lack of targeted therapies, and a poor prognosis. The hypoxic niches within the rapidly growing solid tumors give rise to a stem cell-like phenotype with higher metastasis and drug resistance. To overcome the drug resistance of these regions, we used hypoxia-responsive polymersomes with an encapsulated anticancer drug (doxorubicin, Dox) and a stemness modulator (all-trans-retinoic acid, ATRA). Reductase enzymes overexpressed in the hypoxia reduce the azobenzene linker of the polymers, disrupt the bilayer structure of the polymersomes, and release the encapsulated drugs. We used triple-negative breast cancer (TNBC) as a representative of aggressive and hypoxic solid tumors. We observed that ATRA synergistically enhanced the efficacy of Dox in killing the cancer cells. A synergistic combination of the two drug-encapsulated polymersomes reduced volumes of patient-derived TNBC spheroids by 90%. In contrast, Dox alone decreased the spheroid volumes by 70% and encapsulated Dox by 19%. Mechanistic studies revealed that ATRA inhibited the efflux pumps, leading to a higher concentration of doxorubicin within the TNBC cells. In addition, the combination of encapsulated Dox and ATRA significantly decreased stemness expression of the TNBC cells in hypoxia compared to Dox alone.
An Overview of Palladium-Catalyzed N-alkylation Reactions
Authors: Sabu Soyal , Saranya Padinjare Veetil , Anilkumar Gopinathan
Published: October 2024

N-Alkylation of amines is a vital reaction in the synthesis of numerous bioactive compounds and materials. Among transition metals, palladium has emerged as a particularly effective catalyst for these transformations. The unique advantages of palladium arise from its superior catalytic efficiency, ability to operate under mild conditions, high selectivity and recyclability. Additionally, palladium facilitates the borrowing hydrogen methodology, offering sustainable and environmentally friendly alternatives. This review covers advancements in palladium-catalyzed N-alkylation reactions. The mechanistic insights and practical applications are discussed, providing a comprehensive overview of the current state of research and future directions in this field, covering literature up to 2024.