bluuebunny/crossref_metadata_2025 huggingface dataset:
Sosyal Bilgiler Ders Kitaplarında ve Öğretim Programlarında Değişen ve Değişmeyen Göç Olgusunun İncelenmesi
Authors: PEHLİVAN YILMAZ Ayşegül , GÜNEL Elvan
Published: August 2021

Bu araştırma, 2005 yılından 2020 yılına geçen süreçte göç olgusunun Sosyal Bilgiler Öğretim Programı ve ders kitaplarında nasıl şekillendiğini anlamayı amaçlamaktadır. Araştırmada, nitel araştırma yöntemlerinden doküman incelemesi yöntemi kullanılmıştır. Araştırmada incelenmek üzere doküman olarak 2005 ve 2018 öğretim programlarına bağlı olarak 2005, 2015 ve 2020 yıllarında Milli Eğitim Bakanlığı, Talim ve Terbiye Kurulu tarafından ortaokullarda okutulması kararlaştırılan ders kitapları seçilmiştir. Araştırmada tümevarımsal analizden yararlanılmıştır. Elde edilen veriler satır satır kodlama yapılarak kodlara ulaşılmış, kodlardan temalara ve sonrasında bulgulara ulaşılmıştır. Araştırmada, 2005 yılından 2020 yılına kadar geçen süreçte göç konusunun ders kitaplarında genellikle iç göç ve dış göç bağlamında şekillendiği, 2015 ve 2020 yıllarında göçe ilişkin farklı bakış açılarının ders kitaplarında ele alınmaya başlandığı, ancak göç olgusunun ders kitaplarında sınırlı bir değişime uğradığı bulunmuştur.
PLATAFORMA ARDUINO APLICADA NO DESENVOLVIMENTO DE UM SISTEMA DE COLETA DE DADOS MICRO-AMBIENTAIS EM CASAS DE VEGETAÇÃO
Authors: Marques Filho Aldir Carpes , Rodrigues Jean Paulo , Dal Ponte Gabriel Buligon
Published: August 2021

A coleta de dados e o monitoramento ambiental na agricultura são atividades de alta complexidade, demandando normalmente equipamentos de alto custo. A coleta de dados deve ser realizada preferivelmente próxima ao estrato das culturas vegetais, pois desta forma obtém-se dados fidedignos do microambiente ao qual a planta está inserida. Objetivou-se desenvolver um sistema de coleta de dados, de baixo custo, para a obtenção de parâmetros relacionados à luminosidade, umidade do solo, umidade do ar e temperatura em ambiente agrícola. Utilizou-se a metodologia específica de desenvolvimento de produtos e, plataforma de prototipagem Arduino para montagem do sistema Datalogger. Foram realizados testes de funcionamento em duas casas de vegetação A1 e A2 pelo período de 24 horas. A concepção do sistema, com a utilização de suportes de sensores, permitiu a coleta de dados sem interrupção e com adequada acurácea. A plataforma Arduíno e sensores acessórios mostraram-se perfeitamente aplicáveis para a aquisição e armazenamento de dados em casas de vegetação. O protótipo de Datalogger desenvolvido apresentou redução de custo de 600 até 3000% em relação aos componentes disponíveis no mercado com funcionalidades semelhantes.
Análise da convergência de avaliação de índices de responsabilidade social corporativa no contexto da empresa brasileira
Authors: Freitas Maria Rafaela de Oliveira , Crisóstomo Vicente Lima
Published: August 2021

Este trabalho investiga se há convergência de avaliação da empresa brasileira em índices de Responsabilidade Social Corporativa (RSC). Procedeu-se a análise qualitativa e quantitativa de 1.007 observações de empresas brasileiras avaliadas pelos índices de RSC durante 2013-2017: Índice de Sustentabilidade Empresarial (ISE), Merco Empresas de Reputação Corporativa (MERCO RP), Merco Responsabilidade Social e Governança Corporativa (MERCO RS/GC), e índices de RSC das agências CSRHub e Thomson Reuters. Os resultados indicam que tais índices, embora apresentem metodologias específicas, estão positivamente correlacionados, indicando haver convergência na avaliação do desempenho em RSC da empresa brasileira, sinalizando que o processo de avaliação dos índices parece consistente.
Efectos de las prácticas verdes en la lealtad: propuesta de un modelo para el entorno hotelero colombiano
Authors: Moise Mihaela Simona , Gil-Saura Irene , Ruiz-Molina María Eugenia
Published: August 2021

El propósito de este estudio fue analizar la incidencia de las prácticas verdes como impulsoras para generar confianza, satisfacción y lealtad en los huéspedes. Para ello, a partir de una muestra de 302 huéspedes de hoteles en Bogotá, Colombia, se estimó un modelo de ecuaciones estructurales a través de la regresión de mínimos cuadrados parciales. Los resultados obtenidos evidencian que las prácticas sostenibles contribuyen al aumento de la confianza y la satisfacción de los huéspedes, y que estas, a su vez, influyen positivamente en su lealtad hacia el hotel. Además, dichos resultados ponen de manifiesto que una comprensión más profunda del perfil de los turistas medioambientalmente responsables puede ayudar a los hoteles a diseñar un modelo de negocio amigable con el entorno natural.
Respuestas diferenciales ante las demandas emocionales del trabajo: una revisión de la literatura sobre características individuales y trabajo emocional
Authors: Pujol-Cols Lucas , Dabos Guillermo E.
Published: August 2021

Este artículo tuvo por objetivo describir cómo las características personales de los empleados moldean sus respuestas frente a las situaciones emocionalmente demandantes de su trabajo. Para ello, se realizó una revisión de artículos empíricos publicados en revistas científicas de alto impacto. Los resultados revelan que los rasgos de personalidad, las habilidades emocionales y los motivos del trabajo constituyen las principales características individuales examinadas en la literatura sobre trabajo emocional. Asimismo, indican que estas características individuales asumen un rol fundamental en el trabajo emocional al condicionar las percepciones que los empleados tienen de las reglas emocionales, sus estrategias de regulación emocional y los efectos de los procesos regulatorios sobre la expresión emocional, el bienestar y el desempeño.
İZMİR BÜYÜKŞEHİR BELEDİYESİ İTFAİYE DAİRESİ BAŞKANLIĞININ AFETLERDE ETKİNLİK KAPASİTESİNİN DEĞERLENDİRİLMESİ
Authors: DEMİRCİ Kıvanç , ÖZÇELİK Erkan
Published: August 2021

Araştırmanın temel amacı İzmir Büyükşehir Belediyesi İtfaiye Dairesi Başkanlığının afet
süreçlerindeki etkinlik kapasitesinin ölçülmesi ve bu yolla toplumsal dirençliliğin arttırılmasına katkı
sağlamaktır. Bu amaç doğrultusunda çalışmada ulusal ve uluslararası afet ve itfaiye terminolojisi
açıklandıktan sonra İzmir Büyükşehir Belediyesi İtfaiye Daire Başkanlığının mevcut durumu üzerinde
durulmuştur. Çalışmanın son bölümünde ise daire başkanlığı bünyesinde aktif olarak çalışmakta olan
ve en az bir afet olayında görev alan itfaiye personelleriyle kurum içerisinde yer alan eksikliklerin
tespiti amacıyla yapılan mülakat görüşmesinin çıktılarına yer verilmiştir. Çalışma nitel araştırma
yöntemi olarak kabul edilen yapılandırılmış mülakat yöntemine dayandırılmıştır.
Çalışmada itfaiye personelleri tarafından ifade edilen sorunların başında liyakatsiz personel
alımı, iletişim, personel ve diğer kurumlarla olan koordinasyon eksikliği gelmektedir. Bu eksikliklerin
itfaiye teşkilatı kaynaklarının etkin ve verimli kullanılmasındaki engellerin başında geldiği sonucuna
varılmıştır. Büyük zararların meydana geldiği afetler sonrası yaşanan ruhsal sorunlar, müdahale
sürecinde personellerin kişisel ihtiyaçlarının karşılanmasında yaşanılan eksiklikler ve üst ast
ilişkilerinin etkin yürütülememesi personeller tarafından üzerinde durulan diğer eksiklerdir.
Uzmanlığı ön plana çıkartan eğitim planlaması, liyakata dayalı personel alımı ve yükselme
standartlarının belirlenip objektif olarak uygulanması, afet süreçlerinde etkin kurumların işbirliğini
geliştirecek faaliyetlerin arttırılması, belediye bütçesinin doğru yönetilmesi ve görevli personelin
görev tanımlarının önceden belirlenmesi sorunların çözümünde önerilen yöntemlerin başında
gelmektedir.
THE EFFECTS OF EMPLOYMENT AND FINANCIAL EMPOWERMENT OF WOMEN ON DOMESTIC VIOLENCE: THE CASE OF TURKEY
Authors: ALGÜL Yahya , YARBAŞI İkram Yusuf
Published: August 2021

As one of the fastest developing countries in the world, Turkey has been suffering from

domestic violence significantly in recent decades and it has been one of the hottest topics discussed

both in public and in the national media. On the other hand, it is interesting that according to United

Nations Turkey is one of the leading countries in the MENA regarding the fight against domestic

violence and supporting women’s legal rights in general. However, beyond the legal rights and state

support to women, together with other socioeconomic factors, employment status and financial

empowerment of women may be linked to sexual and physical violence against women. In this study,

it is aimed to investigate this potential relationship by using the “Research on Domestic Violence

Against Women in Turkey” survey data conducted by the Turkish Statistical Institute in 2014. The

multinomial probit model was used to modeling the effects of employment and financial

empowerment on violence against women. According to estimations results, women who have a job

may less likely to experience some types of domestic violence.
TÜRKİYE’DE KONUT KREDİSİ HACMİ İLE SEÇİLMİŞ MAKROEKONOMİK FAKTÖRLER ARASINDAKİ İLİŞKİNİN DEĞERLENDİRİLMESİ
Authors: ATASOY Toygun , TANRIVERMİŞ Harun
Published: August 2021

Konut finansman sistemlerinin geliştirilmesi yoluyla konuta erişimin kolaylaştığı, uzun vadeli borçlanmalar ile konut talebinin karşılanabildiği ve konut yatırımlarının da artış gösterdiği bilinmektedir. İnşaat ve gayrimenkul sektörlerinin ve dolayısıyla konut fiyatlarının birçok makroekonomik faktör ile ilişkili olduğu değerlendirilmektedir. Bu çalışmada; Türkiye’de uzun vadeli konut kredilerini veren finans kuruluşlarının konut kredisi hacminin, konut fiyat endeksi, konut kredisi faiz oranları, inşaat maliyet endeksi, gayrisafi yurt içi hasıla ve sanayi üretim endeksi ile ilişkisi incelenmiştir. Araştırma sonuçlarına göre; konut kredisi hacminin, konut fiyatları, konut kredisi faiz oranları ve inşaat maliyet endeksi ile ilişkili olduğu saptanmıştır. Değişkenler arasında eşbütünleşik bir ilişkinin olduğu, konut kredisi hacminin ve konut kredisi faiz oranlarının konut fiyat endeksinin birer Granger nedeni olduğu ve inşaat maliyetleri ile konut fiyatlarının ise karşılıklı Granger nedensellik içerdiği tespit edilmiştir.
Investigation of Antimicrobial Activity of Lallemantia canescens (L) Fisch & Mey.
Authors: ALTIN Sevgi , AKYÜZ Sümeyye , KAĞAN YENİÇERİ Esma Kübra , KÖKSAL Ekrem , ALTAY Ahmet , ALP Cemalettin
Published: August 2021

Studies on the lethal effects of plants on harmful microorganisms have made them an important and valuable resource for health. Turkey, wherefore the junction center of three phytogeographic regions, is home to numerous medicinal and aromatic plants with its rich flora. L. canescens is a perennial plant that grows in a geography extending from Turkey to Iran, and there are studies on the plant only on its antioxidant capacity and essential oil content. In this study, antimicrobial activity of hexane, ethylacetate, methanol and water extracts of aerial parts of L. canescens, which has known as “Topajdarbaşı” in Turkey, was investigated. Plant samples were collected from Pöske Mount in Erzincan. Antimicrobial activities of extracts were evaluated using disc diffusion method against Gram-negative bacterias (Pseudomonas aeruginosa, Klebsiella pneumoniae, colistin-resistant Escherichia coli, Escherichia coli) and Gram-positive bacterias (Enterococcus faecalis, Staphylococcus aureus, Streptococcus pneumoniae). To conclude, hexane, ethylacetate and methanol extracts of L. canescens showed considerable antimicrobial activity against S.aureus, E.faecalis, S.pneumoniae strains.
INOVAÇÃO DE VALOR E USO DE UMA PLATAFORMA DE IDEIAS POR UMA UNIVERSIDADE BRASILEIRA | VALUE INNOVATION USING AN IDEA PLATFORM AT A BRAZILIAN UNIVERSITY
Authors: Martins Teresa Cristina Monteiro , Zambalde André Luiz
Published: August 2021

Nos últimos anos, instituições públicas de diversos países adoram iniciativas inovação aberta, sobretudo desafios de ideias, visando maior colaboração dos cidadãos na gestão pública. Entretanto, percebe-se a ausência de aprofundamento envolvendo valores e inovação efetivamente agregados por estas iniciativas às organizações e cidadãos. Na presente pesquisa, busca-se discutir e aprofundar investigações neste contexto, utilizando-se o “radar da inovação de valor”: um modelo teórico, proposto por Martins et al. (2019), composto por quatro dimensões e doze fatores críticos para a percepção de inovação em projetos do setor público. Tem-se como objetivo principal aplicar o modelo radar a um desafio de ideias, denominado “Desafio Uni+”, promovido por uma universidade pública brasileira. Trata-se de uma pesquisa aplicada, com objetivos de caráter exploratório-descritivo, abordagens quantitativa e qualitativa e tendo como unidade de análise o “Desafio Uni+”. Como resultados têm-se a análise e a discussão da adequabilidade estatística dos fatores do radar, além da descrição da percepção de inovação de valor associada à participação no “Desafio Uni+”. Conclui-se que o fator Colaboração não atende à adequabilidade estatística e não pode ser considerado para avaliar o projeto Uni+. E que a comunidade acadêmica percebeu o projeto como inovador em relação à abertura e à eficiência para captação de ideias, entretanto, não percebeu, ou não foi adequadamente informada, sobre a geração de valor e implementação das ideias vencedoras do processo. DOI: 10.18226/23190639.v9n1.07 Teresa Cristina Monteiro Martins, UFLA, Brasil, Email: teresacristina.ufla@gmail.comAndré Luiz Zambalde, UFLA, Brasil, Email: zamba@ufla.br Submetido: Agosto, 2020Aceito: Agosto, 2021*Contato para Correspondência
Anti-Inflammatory and Antioxidative Effects of Sumatriptan Against Doxorubicin-Induced Cardiotoxicity in Rat
Authors: Sheibani Mohammad , Faghir-Ghanesefat Hedyeh , Azizi Yaser , Mokhtari Tahmineh , Yousefi‐Manesh Hasan , Sattarzadeh Badkoubeh Roya , Emami Amir Hossein , Dehpour Ahmad Reza
Published: August 2021

The clinical use of doxorubicin as a potent chemotherapeutic agent is limited due to its dose-dependent cardiotoxicity. Oxidative stress and inflammatory pathways have a pivotal role in doxorubicin-induced cardiotoxicity. Sumatriptan, a 5-hydroxytryptamine (5-HT)1B/1D agonist that is mainly used to relieve migraine pain, has suggested exerting protective effects in numerous pathological conditions through antiinflammatory properties. The aim of the present study was to investigate the effects of sumatriptan on doxorubicin-induced cardiotoxicity and the contribution of anti-inflammation and antioxidative responses. Cardiotoxicity was induced by the administration of doxorubicin three times a week (2.5 mg/kg i.p) for two consecutive weeks on male rats. The animals were divided into four groups, including Control, Sumatriptan (0.1 mg/kg) received group, doxorubicin received group, and Doxorubicin+Sumatriptan (0.1 mg/kg) received group. Sumatriptan was administered 30 min before every injection of doxorubicin. On the last day of the second week, the body weight, mortality rate, electrocardiogram (ECG) and histopathological changes, cardiac inotropic study, and biochemical factors were evaluated. The loss of body weight, mortality rate, ECG parameters, reduction of papillary muscle contractility force as well as histopathological scores following administration of doxorubicin indicated severe cardiac damage. However, treatment with sumatriptan inhibited the functional and structural impairment induced by doxorubicin. In addition, sumatriptan could significantly reduce cardiac tissue levels of malondialdehyde (MDA) and tumor necrosis factor-alpha (TNF-α), which were increased in the doxorubicin-treated rats. This study illustrated the protective effects of sumatriptan on decreasing doxorubicin-induced cardiac toxicity and mortality rate in part through inhibition of inflammatory and oxidative stress pathways.
The Association of Socio-Economic Factors, and Smoking Behavior With COPD Severity in an Industrial City of Iran
Authors: Zohal Mohammadali , Rafiei Sima , Esmailzadehha Neda , Jamshidi Sanaz , Rastgoo Nafiseh
Published: August 2021

Socioeconomic and lifestyle factors are regarded as important influencing issues regarding a wide range of chronic diseases, including chronic obstructive pulmonary disease. This study aimed to explore the role of such factors as determinants of disease exacerbation among COPD patients. A cross-sectional study was conducted among 150 COPD patients who were referred to an outpatient respiratory care center in Qazvin, Iran, to undertake respiratory function tests from December 2017 to June 2018. Disease severity was determined by the Initiative for Chronic Obstructive Lung Disease (GOLD) index. Odds ratios were applied to find out factors associated with exacerbation. Study findings affirmed that within COPD severity groups, there were significant differences among patients in terms of educational level, smoking status, income, and occupation. Factors associated with severe COPD were found to be smoking (OR 3.6, 2.6-4.2), lower education (OR 1.4, 0.9-2.6), insufficient income (OR 2.3, 0.6-3.1), and unsupportive family (2.7, 1.5-3.6). Due to the obtained evidence about the effect of socioeconomic status on the prognosis of the disease, it is suggested that clinicians should also consider the nonclinical and social aspects associated with the disease in advancing patients' therapeutic procedures and management algorithms.
La ‘privatización’ de la acción pública de inconstitucionalidad
Authors: Hartmann-Cortés Kevin , Herrera Juan Felipe , Angarita Gabriel Hernando
Published: August 2021

Las ‘cargas argumentativas’ exigidas en las demandas de inconstitucionalidad terminaron de eliminar la naturaleza pública e informal de la acción de inconstitucionalidad. El presente artículo evidencia empíricamente cómo el desarrollo jurisprudencial de la Corte Constitucional ha incentivado su ‘privatización’. Nos referimos a dos fenómenos simultáneos: la restricción generalizada para ejercer el derecho ciudadano de participar en el control del poder político a través de esa figura, y la concentración de su uso y goce en una élite: los abogados. Nuestros modelos probabilísticos advierten el robustecimiento de desigualdades injustificables en el ejercicio y goce de los derechos incorporados en esta acción, tanto entre abogados y no-abogados como entre hombres y mujeres. Señalamos que los efectos de la operación de esta acción deben ser tenidos en cuenta al momento de revisar sus alcances y contenido y sugerimos algunas medidas para su futuro desarrollo.
Las reformas a la justicia durante la vigencia de la Constitución de 1991
Authors: Quinche Ramírez Manuel Fernando
Published: August 2021

Este artículo es uno de los resultados del proyecto de investigación titulado “Reformismo constitucional y constitucionalismo transformador”, uno de cuyos objetivos era el de analizar las características y las dinámicas de las enmiendas introducidas al texto constitucional. Tiene como tema central las reformas a la justicia adelantadas durante la vigencia de la Constitución Política de Colombia de 1991. El texto examina las reformas efectuadas en tres escenarios: el de las enmiendas constitucionales, el de la implementación de programas de descongestión judicial y el de las políticas de desjudicialización y administrativización de la justicia. La tesis señala: i) que luego de treinta años de vigencia de la Constitución y de la expedición de 55 enmiendas constitucionales no se ha efectuado una reforma a la justicia que sea integral y eficaz; ii) que los programas de descongestión judicial no han sido exitosos y vienen perdiendo el carácter excepcional y transitorio para volverse permanentes, y iii) que las políticas de desjudicialización y descongestión incrementan la concentración del poder en la rama ejecutiva, debilitan las redes del control y erosionan la democracia constitucional en Colombia. Se trata de una investigación documental y analítica, que evalúa un tema trascendental en un período definido.
Obaveza ljekara na pružanje medicinskih usluga v. prigovor savjesti u medicini
Authors:   University of Dzemal Bijedic Mostar, Faculty of Law, Mostar, Bosnia and Herzegovina, Čolaković Maja
Published: August 2021

The patient's right to available and accessible healthcare is correlated with the physician's obligation to provide the appropriate medical services. More recently, in medical practice in several countries, there have been an increasing number of cases where physicians (and other healthcare providers) refuse to provide a specific medical service, referring to their religious and moral beliefs i.e. the right to conscientious objection. Do physicians violate their professional obligation to act for the benefit of the patient and provide the necessary medical services? Does this interfere with the patient's right to self-determination and his other rights? Does this lead to discrimination against patients and indirect imposition of physicians' moral and religious beliefs? These are just several questions raised in theory and practice due to the conscientious objection in medicine. This paper explores the doctrinal and legislative approaches of the right to conscientious objection in medicine in Europe and worldwide.
Odgovornost in ukrepi zdravstvenih inštitucij v boju proti odpornim mikrobom
Authors:   University Medical Centre Maribor, Maribor, Slovenia, Knez Lea , Reberšek Gorišek Jelka ,   Alma Mater Europaea, Maribor, Slovenia, Gorišek Miksić Nina ,   University Medical Centre Maribor, Maribor, Slovenia
Published: August 2021

Antimicrobial resistance is one of the significant threats to human health. To maintain the benefits of modern medicine, which hardly relies on antimicrobial treatments, all the stakeholders have to work together towards containing antimicrobial resistance. There are three fundamental strategies to tackle antimicrobial resistance: prudent and supervised antimicrobial use, improved hand hygiene, and improved cleaning of the patient environment.
Farmaceutsko pravo i odgovornost za štetu, osobito s aspekta povrede prava osobnosti
Authors: Kačer Blanka ,   University of Split, Faculty of Law, Split, Croatia
Published: August 2021

The work of a pharmacist is very often an essential part of treating the patients. However, it is also an integral part of modern life, even in cases where it is not only about medicine but also concerning beauty products, vitamins, and more. The special regulation regulates this part of the law – it is necessary to pay attention and find the answers, to several very important questions about the liability for damage, in the pharmaceutical law. The violation of rights relating to personality has been specifically analyzed.
Production and Reproduction Performance of Sahiwal and HF × Sahiwal Cows
Authors: Prasanna J. Sai , Rao S.T. Viroji , Prakash M. Gnana , Rathod Suresh , Kalyani P. , Sharma Major Rajesh
Published: August 2021

Background: Milk production is one of the most important economic traits in dairy cattle. Crossing of zebu cattle (Bos indicus) with temperate cattle breeds (Bos taurus) was undertaken to improve the milk production in India. Crossbreeding has resulted in improved production performance of the dairy animlas over the past few decades. Methods: Data on 50 purebred Sahiwal cows from the Livestock Farm Complex, College of Veterinary Science, Rajendranagar, Hyderabad and 50 Holstein Friesian × Sahiwal crossbred cows maintained at the Military Dairy Farm, Secunderabad were utilized to study the influence of breed and parity on various production and reproduction traits. The various traits studied were: Total lactation milk yield (TLMY) Lactation length (LL), Peak yield (PY), Age at first service (AFS), Age at first calving (AFC), Gestation period (GP), Service period (SP), Dry period (DP) and Calving interval (Cl). Result: In the present study, significant effect of breed was found on the TLMY and PY with the crossbreds recording higher values for both the traits. The means for TLMY, PY, LL, GP, SP, DP and CI were 1768.32±109.67 kg, 10.17±0.50 kg, 304.41±13.00 days, 277.71±2.24 days, 182.60±15.51 days, 167.47±10.68 days and 430.23±13.46 days in Sahiwal and 2983.45±78.32 kg, 14.92±0.36 kg, 324.71±9.29 days, 275.34 days, 181.09±10.91 days, 127.01±7.51, 413.61±9.47 days in crossbred cows respectively. It may be concluded that the productive performance of crossbred cows was better than that of indigenous cows.
Standardization of Different Pre-sowing Seed Treatments on Growth, Yield and Yield Attributing Traits of Kodo Millet (Paspalum scorbiculatum)
Authors: Kavitha Maddipoti , Rai Prashant Kumar , Haritha B. , Kumar R. Karthik , Kumar A. Hemanth , Khandka Sarita
Published: August 2021

Background: Paspalum scorbiculatum is an annual crop and has superior nutritional properties including high micronutrients, dietary fiber content and gluten free. It has low glycemic index (GI) carbohydrate diets help in prevention of Obesity, Diabeties and Cardiovascular diseases, etc. The current study was aimed to find out the suitable pre- sowing seed treatments for Kodo millet. Methods: During the Kharif season 2019- 2020 total of 12 pre- sowing seed treatments were subjected with Botanicals, Magnetic and Electric fields, Thermal (Hot water) treatments and to fix the best treatment based on Seed Quality and Morphological traits of treated seeds. Morphological traits play an major role in crop growth and development where as, the present investigation was carried out with farmer’s variety in field (RBD) design in 3 replications and laboratory (CRD) design in 4 replications in order to “Standardization of different pre- sowing seed treatments on growth, yield and yield attributing traits of Kodo millet (Paspalum scorbiculatum). Seeds were subjected to various pre- sowing seed treatments viz. (T0) control, exposure to Magnetic field at 100 mT, 200 mT, 400 mT for 15,30 and 45 min; exposure to Electric field at 50 mA, 100 mA, 150 mA for 5,10, 15 min. Treatment with botanicals cow dung (5 gm) and Datura leaf extract (2.5 ml) for 12 hrs; Thermal hot water treatment at 46°C and 50°C for 10 min. Result: Among all the treatments, T4-Magnetic field (200 mT) gave the best results in field and lab conditions of field emergence (98.610) and germination% (98.5), Magnetic field (400 mT) shown the good results and significantly higher values of all other yield (45.867, 78.833, 660.480, 165.120) and morphological traits as well as seed quality parameters like shoot length (86.925), root length (44.55), seedling length (13.131), vigour index- I and II (1267.138 and 5.058), fresh (0.343) and dry (0.0524) weight of seedlings and comparatively control (T0) was observed lowest to other treatments. As such, Magnetic treatment is quite effective for seedling establishment to overcome low germination and yield which helps in Qualitative and Quantiative seed production of Millets in sustainable agriculture.
Development of Genome-wide Simple Sequence Repeat Markers from Whole-genome Sequence of Mungbean (Vigna radiata)
Authors: Mayalagu Kanimoli Mathivathana , Adhimoolam Karthikeyan , Nallathambi Jagadeeshselvam , Rajagopalan Veera Ranjani , Balasubramanian Madhumitha , Shihabdeen Madiha Natchi Samu , Natesan Senthil , Muthurajan Raveendran , Manickam Sudha
Published: August 2021

Mungbean is an important pulse crop and it is mainly cultivated in Asia for human consumption. Its small genome and diploid nature make it a well-suited model organism among legume crops. Thus, cost-effective, reliable and highly polymorphic molecular markers distributing the whole genome are needed for diversity, mapping and functional genomics studies in this model species. The whole-genome sequence of mungbean was obtained and used as a source of identification of simple sequence repeats (SSR). The sequence reads were aligned and SSRs detection was performed using the Phobos plugin tandem repeat finder in the Geneious software program. A total of 12 mungbean genotypes were selected to validate the newly developed SSR markers. In the present study, a total of 12, 49,774 and 11, 86, 386 perfect and imperfect SSR repeats were identified from the mungbean genome. The tri-repeats were the most abundant (26.10%), followed by hexa (20.82%), penta (20.45%), tetra (17.65%) and di-repeats (14.95%). We designed 1330 SSR primers based on the genomic sequence of flanking perfect SSRs (Di and tri-repeats). Among them, 50 SSR primers uniformly distributed across the 11 mungbean chromosomes were selected and used to validate 12 mungbean genotypes. The newly developed genomic SSR markers generated in the present study are a valuable genomic resource for the mungbean breeding programs.
​Effect of Seed Treatments and Storage Period on Seed Health Parameters of Pea (Pisum sativum L.) under Ambient Storage Conditions
Authors: Kumar Ravindra , Gupta Anuja , Verma Kumkum , Singh Arjun
Published: August 2021

Background: Pea (Pisum sativum L.) is an important leguminous crop utilized as vegetable and pulse, being an important source of proteins. Pea seeds harbour various mycoflora both in field and during storage, which plays important role in reducing seed viability, germination and vigour inflicting considerable losses in yield and quality. There is scarcely any recommendation available to maintain seed quality during storage of pea seeds, hence present study was carried out. Methods: Seeds of pea (cvs. Azad P. 1 and Arkel) were treated with Captan and Carbendazim 50%WP fungicides @ 2.0 g/Kg seed and stored under ambient conditions. The samples were drawn at three months interval to assess the effect of storage on seed quality parameters. The vigour index I, per cent germination and speed of germination of these seed samples were determined using ISTA rules. The detection of associated mycoflora in pea (Pisum sativum L.) seed samples was carried out by standard blotter method as recommended by International Seed Testing Association. Result: Total fourteen fungal species were found associated with different pea seed samples. Out of these, maximum incidence of Alternaria alternata (21.36%) followed by Aspergillus flavus (15.53%), A. fumigatus (14.56%), A. niger (11.60%) and Rhizopus stolonifer (9.71%), were recorded on untreated seed of pea cv. Azad P. 1, after 18 months of storage. The germination, speed of germination and vigour index of stored seed reduced with increase in storage period, whereas fungal incidence increased with the increasing storage period. Among the tested cultivars, germination in pea (cv. Arkel) remained above IMSCS even after 18 months of storage under ambient storage conditions. The maximum percent germination (99.0) was found in pea cv. Azad P. 1 seeds treated with Captan at 3 months of storage, whereas minimum percent germination (49.5) was found in untreated seed of pea cv. Azad P. 1 after 18 months of storage. The maximum speed of germination (23.88) was found in Captan treated seed of pea cv. Arkel at 0 month of storage and minimum speed of germination (3.52) was found in untreated seed of pea cv. Azad P. 1 at 18 months of storage. The maximum vigour index I (2339) was found in pea cv. Azad P. 1 (Captan treated seed) at 3 months of storage and minimum vigour index I (431) was found in untreated seed of pea cv. Azad P. 1 after 18 months of storage.
The Moderating Role of Work Discipline on The Links Between Locus of Control and Work Ethics in Local Government Employees
Authors: Siswanto Siswanto , Darus Umi
Published: August 2021

The aim of this study is to analyze the role of internal locus of control and external locus of control on work ethics. In addition, this study also analyzes the role of work discipline as a mediating variable. This study uses a quantitative approach. The number of research samples is 114 people. They are civil servants in the city government environment in East Java. Data analysis uses path analysis. The analysis shows that the two-locus of control variables have a positive effect on work ethics. Internal locus of control also has a positive effect on work discipline. Meanwhile, external locus of control does not affect work discipline. Analyst results show that work discipline has a role as a mediating variable. Meanwhile, in the external locus of control of work ethics, work discipline does not act as a mediating variable.
Chrononutrition and Breast Milk: A Review of the Circadian Variation of Hormones Present in Human Milk
Authors: Moyo Gugulethu T. , Thomas-Jackson Shera C. , Childress Allison , Dawson John , Thompson Leslie D. , Oldewage-Theron Wilna
Published: August 2021

Introduction

Breast milk contains a wide range of hormones, nutrients, and bioactive compounds. Chrononutrition looks at the interaction between food, both meal timing and meal composition, and circadian rhythms.

Method

This review is a continuation on series on chrononutrition and breast milk. All human studies published in English were included regardless of location or year of publication.

Results

This review identifies the hormonal circadian variation researched in breast milk to date for melatonin, cortisol, cortisone, leptin, and insulin.

Conclusion

The circadian variation observed in some hormones reinforces the superiority of breast milk over formula milk. Melatonin has been the most studied, but more research for all the hormones is needed due to various gaps in the literature and varying levels of study quality. There is insufficient evidence to make recommendations specifically targeting the lactating mother, but we identify and recommend several ideas for future research.
Democratic Governance and Social Service Delivery in Africa: the case of Taraba State, Nigeria
Authors: Onuoha Jonah I. , Lawi Rimamchaten A. , Onuh Paul A. , Onuoha Ifeanyi J.
Published: August 2021

Postcolonial leadership is implicated in the distorted development and crisis of governance in Nigeria. The political leadership emerged from authoritarian traditions of the colonial state and pursued self-interests against collective societal interests; the mode of the emergence of the leaders as well as the context in which they operate usually impact on the nature and trend of social welfare provisioning. Relying on data from secondary sources, this study examined the impact of democratic governance on social service delivery with Taraba State and education as a case study. The data analysis was based on qualitative descriptive analysis. We found that the education sector under the two administrations between 1999 and 2014, was not prioritized in budgetary allocation, in contravention of UNESCO recommendation that 26% of the budget be dedicated to education. The study recommends, among others, that the government must show commitment to education as a matter of deliberate policy to allocate the required minimum percentage pecked by UNESCO to enhance educational development in Taraba state.
Chest Wall Reconstruction for the Treatment of Lung Herniation and Respiratory Failure 1 Month after Emergency Thoracotomy in a Patient with Traumatic Flail Chest
Authors: Seok Junepill , Wang Il Jae
Published: August 2021

We report a case of delayed chest wall reconstruction after thoracotomy. A 53-year-old female, a victim of a motor vehicle accident, presented with bilateral multiple rib fractures with flail motion and multiple extrathoracic injuries. Whole-body computed tomography revealed multiple fractures of the bilateral ribs, clavicle, and scapula, and bilateral hemopneumothorax with severe lung contusions. Active hemorrhage was also found in the anterior pelvis, which was treated by angioembolization. The patient was transferred to the surgical intensive care unit for follow-up. We planned to perform surgical stabilization of rib fractures (SSRF) because her lung condition did not seem favorable for general anesthesia. Within a few hours, however, massive hemorrhage (presumably due to coagulopathy) drained through the thoracic drainage catheter. We performed an exploratory thoracotomy in the operating room. We initially planned to perform exploratory thoracotomy and “on the way out” SSRF. In the operating room, the hemorrhage was controlled; however, her condition deteriorated and SSRF could not be completed. SSRF was completed after about a month owing to other medical conditions, and the patient was weaned successfully.
THE CORRELATION BETWEEN WATER, SANITATION, AND HYGIENE WITH SOIL-TRANSMITTED HELMINTHS INFECTION AMONG ELEMENTARY SCHOOL CHILDREN OF ARU ISLANDS DISTRICT, MALUKU
Authors: Konstantin Tiffany , Tantular Indah Setyawati , Athiyyah Alpha Fardah , Rossyanti Lynda
Published: August 2021

ABSTRACTSoil-Transmitted Helminths (STH) infection is the most common intestinal parasite infection in Indonesia. STH infection can interfere with child development and cause cognitive impairment in severe cases.  The school-age group is the most susceptible to STH infection because of direct contact with soil in the school yard. STH infection incidence can be avoided by adequate water, healthy latrines, and good hygiene and can be improved by proper interventions. This study aimed to analyze the correlation between Water, Sanitation, and Hygiene (WASH) with STH infection in Aru Islands District, Maluku. This study used a cross-sectional design and was conducted in Elementary Schools in Karangguli and Wokam villages, Aru Islands district, Maluku. One hundred and six stool samples were collected from both villages. The sociodemographic and WASH data were collected using the interview method. Stool samples were collected and examined for STH infection using a direct smear technique on the light microscope. Data statistical analysis was performed by the SPSS program using the Chi-square or Fischer’s Exact test. The examination results showed that 73 students (68.9%) were infected with STH. The bivariate analysis showed that water source (p = 0.000002), defecation place (p = 0.002), and washing hands after defecation (p = 0.048) were all significantly correlated with STH infection. This study concluded that WASH variables which were water source, defecation place, and washing hands after defecation had a significant correlation with STH infection. Keywords: Water, Sanitation, and Hygiene (WASH); soil-transmitted helminths infection; elementary school students.
FACTORS RELATED TO BREASTMILK PRODUCTION ON POSTPARTUM MOTHERS IN EAST PONTIANAK, WEST KALIMANTAN
Authors: Widyastutik Otik , CHARTASIM YUWAN , TRISNAWATI ELLY , SELVIANA SELVIANA
Published: August 2021

ABSTRACTProducing breastmilk is a mother’s ability for the next six weeks after giving birth. Based on data from the Health Office of Pontianak City, exclusive breastfeeding coverage is 25% in East Pontianak District. A preliminary study conducted in East Pontianak Sub district, seven out of ten respondents who underwent breastfeeding, their breastmilk was not running well. There are 70% of babies experienced weight increment below 500 grams/month. In addition, 70% mothers drinking less than twelve glasses/day, 70% mothers do not receive support from their husbands in breastfeeding process, 60% mothers have never been exposed to breastfeeding information, and 50% mothers experienced moderate anxiety levels after giving birth. The research aimed to determine the determinants of postpartum mother's milk production in East Pontianak District. This research is observational research with a cross-sectional approach, and the research subject is 48 postpartum mothers. The results showed that the determinant factor could be seen from the relationship of fluid intake (p-value = 0.000), husband's support (p-value=0.000), information exposure (p-value=0.010), supplement (p-value=0.000), and energy intake (p-value=0.000), to breast milk production. Recommendations addressed to the community health center such as work more active in providing counselling, activating cadres by providing practices. Therefore, they can assist in providing knowledge about breastfeeding and making creative promotional media.Keywords : breast milk production, postpartum, nutrition intake
Uji Stabilitas Formulasi Hand and Body Cream Ekstrak Etanol Kulit Buah Naga Merah (Hylocereus lemairei)
Authors: Nurfita Erviana , Mayefis Delladari , Umar Salman
Published: August 2021

Pendahuluan: Kulit buah naga merah (Hylocereus lemairei) memiliki potensi sebagai bahan baku kosmetika, karena memiliki kandungan antioksidan yang cukup tinggi yang dapat dimanfaatkan sebagai pelembab kulit dan mencegah kulit kering. Tujuan: Penelitian ini bertujuan untuk mengetahui stabilitas fisik ekstrak kulit buah naga merah (Hylocereus lemairei) yang diformulasikan menjadi sediaan krim yang dapat dimanfaatkan sebagai pelembab pada tangan maupun seluruh badan. Metode: Krim dibuat dalam 3 seri konsentrasi yaitu 4%, 6% dan 8% serta basis krim sebagai kontrol negatif. Pengujian stabilitas krim meliputi, organoleptis, homogenitas, tipe krim, uji pH, daya sebar, viskositas, uji iritasi kulit, uji kesukaan serta uji stabilitas sediaan meliputi uji cycling test, uji mekanik, dan uji stabilitas selama penyimpanan pada suhu rendah (4 ± 2°C) dan suhu kamar (30°C).  Hasil: Hasil penelitian menunjukkan bahwa ekstrak kulit buah naga merah (Hylocereus lemairei) dapat diformulasikan dalam bentuk krim serta memiliki kestabilan yang cukup baik selama proses penyimpanan. Kesimpulan: Ekstrak kulit buah naga merah (Hylocereus lemairei) memiliki kestabilan yang baik sebagai sediaan krim yang dapat digunakan sebagai pelembab kulit tangan dan seluruh tubuh.
Aktivitas Gel Fraksi Etil Asetat dari Ekstrak Etanol Daun Ubi Jalar Untuk Pengobatan Luka Bakar
Authors: Rahmadani Hanifah Fajar , Pratimasari Diah , Amin Muhammad Saiful
Published: August 2021

Pendahuluan: Luka bakar merupakan peristiwa hilangnya jaringan yang disebabkan kontak dengan sumber panas. Penggunaan bahan alam sebagai pengobatan luka bakar menggantikan penggunaan obat dengan bahan sintetis yang dapat memberikan efek samping. Bahan alam yang memiliki aktivitas sebagai pengobatan luka bakar salah satunya adalah daun ubi jalar (Ipomoea batatas L.). Tujuan: Penelitian ini berfokus pada penggunaan fraksi etil asetat dari ektrak etanol daun ubi jalar (Ipomoea batatas L.) sebagai alternatif dalam pengobatan luka bakar. Metode: Ekstraksi senyawa dalam daun ubi jalar menggunakan etanol 70% dan difraksinasi menggunakan pelarut etil asetat. Fraksi etil asetat daun ubi jalar (Ipomoea batatas L.) diidentifikasi untuk melihat senyawa metabolit sekunder. Fraksi etil asetat daun ubi jalar (Ipomoea batatas L.) diformulasi dalam bentuk gel dengan konsentrasi 1%, 2% dan 3%. Uji luka bakar menggunakan hewan uji tikus galur wistar jantan yang telah diberikan perlakuan luka bakar derajat 2. Pembuatan luka bakar menggunakan logam berdiameter 2 cm yang dipanaskan pada api bunsen. Pengamatan luka bakar dilakukan setiap 3 hari sekali dengan mengukur diameter luka bakar. Penurunan luka bakar diolah menggunakan Uji One Way Anova dan dibuat grafik penurunan luka bakar. Hasil: Hasil analisa statistik dengan menggunakan Uji One Way Anova menunjukkan nilai p > 0,05 yang berarti tidak ada perbedaan signifikan secara statistik. Namun, secara kualitatif menunjukkan trend penurunan luka bakar, grafik tertinggi diperoleh pada pemberian F2 dengan konsentrasi fraksi etil asetat daun ubi jalar (Ipomoea batatas L.) 2%. Kesimpulan: Fraksi etil asetat daun ubi jalar (Ipomoea batatas L.) memberikan aktivitas pengobatan luka bakar.
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family
Authors: Kusumawati Idha , Mahatmaputra Syailendra , Hadi Rohman , Rohmania Rohmania , Rullyansyah Subhan , Yusuf Helmy , Rahman Abdul
Published: August 2021

Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these plants have been widely used traditionally for various therapies, one of which is an aphrodisiac. Objective: The purpose of this study was to determine the aphrodisiac activity of the fruits of three pepper plants, Piper nigrum, Piper retrofractum, and Piper cubeba to prove their traditional use. Methods: The level of piperin, the active compound of plants from the family Piperaceae, was also determined in the ethanolic extract of those three fruits of the pepper plant. The aphrodisiac activity was determined by counting the number of introducing and mounting mice. The acute toxicity test of the extract was carried out according to the OECD-423 guidelines. Results: The ethanolic extract of Piper nigrum fruits had the highest piperin concentration, while the ethanolic extract of Piper retrofractum fruits had the highest aphrodisiac activity, according to the findings. During the entire duration of the acute toxicity study, no signs of toxicity or mortality were discovered.Conclusion: This study proves that all fruits of three species of pepper plants exhibit aphrodisiac activity. Furthermore, this study also shows that not only piperin is responsible for the aphrodisiac effect.
An Immunometabolic Pathway for Hyperglycemia?-Commentary on: Packed Red Blood Cells Inhibit T-Cell Activation via ROS-Dependent Signaling Pathways
Authors: Papadopoulos Charalampos , Anagnostopoulos Konstantinos , Tentes Ioannis
Published: August 2021

In this commentary we discuss the novel findings of Gerner et al. In their study, it was found that red blood cells inhibit T cell activation through scavenging of reactive oxygen species. We propose a novel immunometabolic pathway, based on previous studies which showed that hyperglycemia abolished the antioxidant function of red blood cells.
Alphavirus-driven Interferon Gamma (IFNg) Expression Inhibits Tumour Growth in Orthotopic 4T1 Breast Cancer Model
Authors: Trofimova Olga , Korotkaja Ksenija , Skrastina Dace , Jansons Juris , Spunde Karina , Isaguliants Maria , Zajakina Anna
Published: August 2021

Interferon gamma (IFNg) is a pleiotropic cytokine that can potentially reprogramme the tumour microenvironment. However, the antitumour immunomodulatory properties of IFNg still need to be validated due to variable therapeutic outcomes in preclinical and clinical studies. We developed a replication-deficient Semliki Forest virus vector expressing IFNg (SFV/IFNg) and evaluated its immunomodulatory antitumour potential in vitro in a model of 3D spheroids and in vivo in immunocompetent 4T1 mouse breast cancer model. We demonstrated that SFV-derived IFN-g stimulated bone marrow macrophages to acquire the tumoricidal M1 phenotype in 3D nonattached conditions. Coculturing SFV/IFNg-infected 4T1 spheroids with BMDMs inhibited spheroid growth. In the orthotopic 4T1 mouse model, intratumoural administration of SFV/IFNg virus particles alone or in combination with the Pam3CSK4 TLR2/1 ligand led to significant inhibition of tumour growth compared to the administration of the control SFV/Luc virus particles. Analysis of the composition of intra-tumoural lymphoid cells isolated from tumours after SFV/IFNg treatment revealed an increase in CD4+ and CD8+ and a decrease in T-reg (CD4+/CD25+/FoxP3+) cell populations. Furthermore, a significant decrease in the populations of cells bearing myeloid cell markers CD11b, CD38 and CD206 was observed. In conclusion, the SFV/IFNg vector induces a therapeutic antitumour T-cell response and inhibits myeloid cell infiltration in treated tumours.
How Viruses Use the VCP/p97 ATPase Molecular Machine
Authors: Das Poulami , Dudley Jaquelin P.
Published: August 2021

Viruses are obligate intracellular parasites that are dependent on host factors for their replication. One such host protein, p97 or the valosin-containing protein (VCP), is a highly conserved AAA ATPase that facilitates replication of diverse RNA- and DNA-containing viruses. The wide range of cellular functions attributed to this ATPase is consistent with its participation in multiple steps of the virus life cycle from entry and uncoating to viral egress. Studies of VCP/p97 interactions with viruses will provide important information about host processes and cell biology, but also viral strategies that take advantage of these host functions. The critical role of p97 in viral replication might be exploited as a target for development of pan-antiviral drugs that exceed the capability of virus-specific vaccines or therapeutics.