bluuebunny/crossref_metadata_2025 huggingface dataset:
Short-term and sustained effects of a three-week neuro-developmental treatment intensive: A case series report
Authors: Swiggum Mary Scott , Knowlton Jane , Powers Denise
Published: December 2020

BACKGROUND: Neuro-Developmental Treatment (NDT) currently embraces evidence-based concepts of motor control, motor learning and neuroplasticity. However, most research has been performed on outdated models of NDT. OBJECTIVE: This case series examines the short- and long-term outcomes of a three-week intensive using contemporary NDT interventions. METHODS: Six children, 2–10 years old with neurologic disorders and Gross Motor Function Classification System (GMFCS) levels I-III participated in the intervention. The three-week intensive included 60 minutes of physical, occupational and speech therapy 3–5 times weekly. RESULTS: All children demonstrated Gross Motor Function Measure-66 gains of medium to large effect sizes. These gains were maintained or improved upon 3 months’ post conclusion of the intensive intervention. CONCLUSIONS: This study supports emerging research regarding the effectiveness of intensive intervention and further study of current NDT interventions.
Exploring the frontiers of vestibular migraine: A case series
Authors: Domínguez-Durán Emilio , Doménech-Vadillo Esther , Bécares-Martínez Carmen , Montilla-Ibáñez María Alharilla , Álvarez-Morujo de Sande María Guadalupe , González-Aguado Rocío , Guerra-Jiménez Gloria
Published: December 2020

INTRODUCTION: Patients with episodic vestibular syndrome (EVS) whose symptoms resemble those of vestibular migraine (VM) but who do not meet the criteria for it are common. OBJECTIVE: To describe those patients suffering from EVS in whom defined etiologies have been ruled out in order to determine if their symptoms can be linked to VM. MATERIAL AND METHODS: Prospective multicenter study. The medical records of patients with VM and patients with EVS suggestive of VM but not meeting the criteria for it were examined. The characteristics of headache, the number and the length of attacks, the association of vestibular symptoms and headache, the intensity of symptoms and the response to treatment were recorded. RESULTS: 58 patients met the criteria for VM or probable VM; 30 did not. All of the symptoms improved significantly in the treated patients with VM or probable VM; in the rest of the treated patients, only the vestibular symptoms improved. CONCLUSION: A subgroup of patients that cannot be attributed to any known vestibulopathy according to present day VM criteria profited from migraine treatment, suggesting that their vestibular symptoms belong to the migraine spectrum; whereas some do not, yet our analysis could not identify distinctive features that allowed subgroup attribution.
Elaboration of standards and quality of railway rails
Authors: Smirnov L. A. , Rabovskii V. A. , Dobuzhskaya A. B. , Yunin G. N. , Borts A. I.
Published: December 2020

Russian national standards for rails establish technical requirements, acceptance rules and quality control methods. These are very important to ensure the quality and service durability of rails. Requirements for rail production variation within a period from 1960 to the present considered, peculiarities of their accounting in the standards shown. It was demonstrated that stricter requirements to rails resulted in the development of new steel compositions, the creation and introduction of new technological processes in steel production, rail rolling and heat treatment, as well as new methods of production quality control. Basic technical requirements for rails produced according to the national standard of theRussian Federationand to the European Norm presented. It was pointed out that the current national standard GOST R 51685‒2013 was elaborated accounting the requirements of the latest foreign standard EN 3674-1:2011+A1:2017. However, the former is not equivalent to the latter because it pertains to Russian rail types and contains requirements corresponding to the Russian climatic and geographical conditions, as well as the track facilities system used by OJSC RZD. It was shown that rails, meeting the current standard requirements, in terms of operational resistivity exceed the resistivity level of best foreign analogues. At present, a new standard is being elaborated accounting the need of increasing the service life of railway rails under conditions of high load, low climatic temperatures, higher-speed combined train operation and high-speed running, and high working capacity. The list of key issues presented, that are mirrored in the new standard draft, which accounts for the goal of mastering new rail categories and the increased requirements of OJSC RZD to rails quality.
State and development scenarios for export of food industry waste and feed for animals in Russia and Stavropol territory
Authors: Vorob'eva Natal'ya
Published: December 2020

Abstract. The purpose of the work is to identify the main commodity-geographical trends in the development of the export potential of food and processing industry waste and animal feed in Russia and the Stavropol territory, on the basis of which to formulate scenarios for the development of exports of this segment in the world market. The methodological basis is a set of statistical, economic-mathematical and descriptive methods. The article examines the state, dynamic and structural trends in the export of food waste and animal feed in Russia and the Stavropol territory. Results. The trends of changes in the commodity-geographical structure of the export of food industry waste and animal feed in Russia and the Stavropol territory are revealed. It is concluded that there is an urgent need to expand the production and export of food waste and animal feed in the regions of the Russian Federation, which should be based on scenarios for the development of the world market, in combination with the established opportunities and threats for agro-oriented enterprises, in particular, allowing to identify several potential niches for commodity and territorial development of the Stavropol territory. The novelty of the results. Identified “empirical trends” in the implementation of the export potential of the Stavropol territory, consisting in increasing the volume of exports of traditional products in priority geographical areas, and representing new trends in the development of macro- and regional agro-industrial complex. The paper substantiates the growth of deliveries in the future according to the identified export targets of the product group “Waste from the food industry and animal feed” in the Stavropol territory (mainly to the CIS countries, Italy and Spain), as well as the need to form communications and logistics, allowing to form “an export-oriented platform” In the Stavropol economy.
Burden of malignant melanoma in Ukraine in 2002–2013: incidence, mortality and survival
Authors: Korovin S. , Fedorenko Z. , Michailovich Yu. , Kukushkina M. , Sekerija M. , Ryzhov A.
Published: December 2020

Summary. Background: The malignant melanoma (MM) incidence rates were increasing and later stabilizing in many regions of the world, while in South-Eastern Europe incidence rates are uniformly increasing and mortality rates are higher. Aim: To describe burden of MM in Ukraine in terms of incidence, mortality and survival by sex, age and stage for the period 2002–2013 and compare with European countries. Materials and Methods: Database of the National Cancer Registry of Ukraine was used to extract MM incidence cases; number of MM deaths was obtained from the official mortality statistics. Age-standardised and age-specific incidence and mortality rates were calculated by sex, age groups (15–39, 40–59 and 60+); estimated annual percent of change was used to describe trends. Proportions of new cases by stage of disease and calendar period (2002–2007 vs 2008–2013) were compared as well as net survival estimates. Results: In Ukraine, MM was more common in females (age-standardised 5.3 per 100,000 in 2013; annual percent of change 3.5%) than in males (5.1 per 100,000; 4.1%); around 50% of them diagnosed in the age group 60+. The observed increase in proportion of new cases with early stage (I–II) was due to stage II cases. The slight increase in mortality rates in males or stability in females were not accompanied with increase of survival. Net MM survival was consistently lower comparing to European countries. Conclusion: More resources should be targeted to increase the capacity of healthcare in diagnostics and treatment of malignant melanoma, but also in promoting healthcare and education in Ukraine.
Design and Implementation of IOT Based Smart Water Distribution System
Authors: Devi B. Nantheni , Kowsalya G. , Senbagam R.
Published: December 2020

The aim of this project is to manage and plan the usage of water using IoT. This system can be easily installed in residential societies. Water level measurement is very important in some water related fields. This project permits both meter reader as well as individual domestic/ industrial consumers to use regular smart phones. Flow sensor is placed in pipes which continuously inform the water level at the current time to the web server. This information will be updated on the cloud and using an android application, user can visualize the water level on a smart phone anywhere that is connected to internet. So there is a need to monitor and protect the water with a real time water quality monitoring system in order to make active measurement to reduce contamination.
A Review on Lean Thinking and It's applicability for Implementation on Farming
Authors: Mokhadkar P. A. , Sambhe R. U. , Gandhewar V. R.
Published: December 2020

The lean thinking accentuates on the philosophy of continuously improving performance by systematically eliminating wastes. Lean thinking [1] was introduced to extend the concept from manufacturing floor to various fields like health care, supply chain, service industries, construction, hotel industries etc. Experience shows that adopting lean thinking requires abandoning deeply engrained mainstream management thought routines and this is never easy. As various lean tools when applied to industries results in development. Now this is the time to adopt this valuable tool of development in agriculture field for changing its status. This paper is intended to provide an overview on concept of lean thinking and its applicability for implementation on farming by conferring with various lean tools.
The Impact of Economic Indicators on Financial Performance of Non-financial Firms on Ghana Stock Exchange
Authors: Donkor Mary , Kong Yusheng , Antwi Stephen Kwadwo , Musah Mohammed , Twum Florence Appiah
Published: December 2020

Financial performance is one of the basic indicators that investors and creditors check in accessing the performance of firms. The purpose of this paper is to empirically examine the impact of economic indicators on financial performance of quoted non-financial firms on the Ghana Stock Exchange (GSE). The study focuses on the impact of RealGDP, Exchange rate, Inflation, Unemployment and Interest rate as determinant of economic indicators whereas Sales growth, Company size, Leverage and Efficiency from firms specific are used as controlled variables in checking the effect of these indicators on financial performance of these firms. ROA and ROE were used as proxies for financial performance of the listed firms. The study employed a panel data of 21 listed non-financial firms from the period of 2008 to 2017. The result revealed that Real GDP and inflation have significant positive impact on ROE. On the contrarily, economic indicators used for this study showed no level of significance with ROA. Company size recorded positive and negative significant impact on ROA and ROE respectively, sales growth and efficiency were statistically significant with ROA. The study recommends government and regulatory authorities to come out with good policies that will help boost the economic activities in the country and drop inflation rate since they have the tendency of affecting non-financial firms’ performance. Moreover, management must ensure full utilization of its internal resources by focusing on diversification and expansion since company size, efficiency and sales growth affect the return on assets and equity of firms. In addition, management should warily consider inflation rate when making financial decision due to its impact on financial performance.
Analyse des rêves et des sentiments: étude de cas dans une école municipale d’Imperatriz – MA
Authors: Araujo Marli Da Silva , Santos Nícia De Oliveira
Published: December 2020

Cet article visait à mieux comprendre les façons de penser et de rêver des élèves de 4e et 5e année, d’une école municipale située dans la zone rurale d’Imperatriz – MA, qui vivent sous la conditionnalité de la pauvreté. Une brève analyse de la pauvreté a été faite au Brésil et à Maranhão, nous avons remarqué que de nombreux changements ont eu lieu dans les politiques publiques brésiliennes, afin de changer la réalité de nombreux enfants et jeunes dans la pauvreté ou l’extrême pauvreté. Nous citons l’éducation brésilienne comme un point de repère historique important. Nous soulignons la pauvreté dans les écoles publiques et la possibilité pour ces élèves d’apprendre et de créer des connaissances importantes pour la vie future. L’éducation et les garanties de citoyenneté des enfants et des adolescents sont considérées comme une forme de construction collective. La recherche a été développée dans une approche qualitative, axée sur la phénoménologie, et des entrevues semi-structurées ont été utilisées dans la collecte de données. Car il fallait donner aux élèves l’occasion de s’exprimer librement sur leurs rêves et leurs désirs d’avenir sans pauvreté. Nous avons été en contact avec la réalité des élèves et de leurs familles, nous connaissons l’école où les élèves étudient et un peu sur leurs rêves, leurs désirs et leur vision d’un avenir sans pauvreté. Compte tenu de la pertinence du cadre théorique, nous avons passé en revue des documents et des auteurs traitant du sujet, tels que : Arroyo (2015), Freire (2005), Leite (2017), Pinzani et Leão Rego (2015), Reis (2011), entre autres.
PEMANFAATKAN POTENSI LINGKUNGAN, MELALUI DAUR ULANG SAMPAH BOTOL PLASTIK MENJADI BAHAN BAKAR BIOSOLAR DI KAMPUNG CIPAKEL DESA LEUWEUNG KOLOT
Authors: Hsubky Badruddin , Suaeb Fajar , Indriyani Adisti Fitri
Published: December 2020

Sampah plastik merupakan permasalahan lingkungan hidup yang dihadapi oleh masyarakat indonesia dan dunia. Sampah plastik adalah salah satu sumber pencemaran lingkungan hidup. Plastik merupakan produk serbaguna, ringan, fleksibel, tahan kelemapan, kuat, dan relatifmurah. Pemnafaatan sampah plastik juga dapat dijadikan suatu produk kreatiitas. Seperti mendaur ulang plastik menjadi tas, hiasan ruangan, baju, dan seni-seni lainnya. Penanganan sampah plastik yang sudah banyak diterapkan adalah dengan Konsep 3R (Reuse, Reduce danRecycle) dan alternatif lain yang sudah banyak diteliti adalah daur ulang sampah plastik dijadikan Bahan Bakar Biosolar Murni. Biosolar merupakan bahan bakar mesin disel yang terbuat dari bahan terbarukan atau secara khusus merupakan bahan bakar yang terdiri atasester alkil dari asam-asam lemak yang dibuat dari minyak nabati, minyak hewani atau dari minyak goreng bekas/daur ulang melalui proses tertentu
MEWUJUDKAN MASYARAKAT DESA TEGALLEGA YANG SADAR AKAN PENDIDIKAN DAN KEMANDIRIAN
Authors: Muniroh Leny , Ikhtiono Gunawan , Fikriansyah Muhamad
Published: December 2020

Kuliah Kerja Nyata (KKN) merupakan suatu kegiatan pengabdian mahasiswa terhadap masyarakat yang wajib dilaksanakan oleh seluruh mahasiswa yang sudah mulai memasuki semester 7 di Universitas Ibn Khaldun Bogor. Adapun tujuan dari kegiatan KKN adalah melatih mahasiswa untuk belajar  mengindetifikasi, mencari alternatif solusi pemecahan masalah yang ada di tengah-tengah masyarakat, selain itu melalui KKN mahasiswa akan mendapatkan pengalaman hidup yang mungkin tidak diperoleh selama kegiatan pembelajaran dibangku kuliah. Pada tanggal 6 Agustus s.d. 6 September 2019 kami telah melaksanakan program Kuliah Kerja Nyata (KKN) di Desa Tegallega. Desa Tegallega adalah salah satu desa yang  terletak di  Kecamatan Cigudeg, Kabupaten Bogor yang terbentuk atau berdiri sejak tanggal 18 Maret 1984 atas dasar pemekaran dari Desa Batujajar.  Dalam progam Kuliah Kerja Nyata (KKN) di Desa Tegallega ini kami telah menjalankan beberapa progam-progam unggulan pada setiap bidang diantaranya  pada bidang pendidikan yaitu learn and fun dalam pembelajaran Bahasa Inggris, education competition pada bidang agama, pebuatan plang petunjuk jalan  pada bidang teknik, penyuluhan mencuci tangan (PHBS)  pada bidang kesehatan, serta Market Day pada bidang  ekonomi. Semua program dapat terlaksana dengan baik dan lancar karena terdapat kerjasama yang baik antara semua anggota kelompok KKN  49-50, masyarakat, maupun pihak desa.
MEMBANGUN LITERASI EKONOMI DAN PENGELOLAAN SAMPAH PADA MASYARAKAT DENGAN PENDEKATAN KULTURAL
Authors: Maulana Hendri , Redjeki Indah Sri , Ramadhan Pri Rahmantiyo
Published: December 2020

Serangkaian langkah yang terpadu untuk membuka cakrawala berpikir sehingga mampu bersikap dengan tepat. literasi ekonomi akan berpengaruh juga pada bagaimana mendorong kepekaan akan bagaimana meningkatkan pola pilihan yang cerdas. Mahasiswa memperoleh pengalaman belajar melalui keterlibatan dalam masyarakat yang secara langsung menemukan, merumuskan, memecahkan dan menanggulangi permasalahan yang berada di lapangan tentang sampah rumah tangga organic dan anorganik dengan metode 3R (Reduce, Reuse, Recycle) sampah plastik yang tidak mudah terurai dangan pengelolaan yang tepat yaitu menjadi Paving Block dengan dasar sampah pelastik dilebur menjadi padat. Adapun khalayak sasaran dari pemberdayaan masyarakat yang kami lakukan yaitu warga dan anak diperkenalkan tetang menjaga kebersihan lingkungan terhadapa sampah. program-program unggulan KKN 53 dan 54 adalah Penyuluhan Penyakit DBD dan Pengelolaan Sampah.
MENINGKATKAN SUMBER DAYA MANUSIA DI KP. BOLANG MELALUI PROGRAM PENDIDIKAN, SOSIAL, EKONOMI, HUKUM, DAN KESEHATAN BERBASIS IMTAQ
Authors: Chotimah Indira , Kusumah Anuraga , Dwiputra Muhammad Andika
Published: December 2020

Desa Argapura merupakan satu dari sekian desa yang terletak di kecamatan Cigudeg, kabupaten Bogor, provinsi Jawa Barat, Indonesia. Masyarakat di daerah tersebut, sebagian besar berprofesi sebagai petani. Walau di sisi lain, ada yang berprofesi sebagai guru, tukang ojek, pedagang kaki lima, dan lain sebagainya. Pada tanggal 6 Agustus 2019 sampai dengan tangal 6 September 2019, alhamdulillah kami telah melaksanakan kegiatan KKN. Selama kurang lebih satu bulan di kampung Bolang, desa Argapura, kecamatan Cigudeg. Adapun tujuan dari pelaksanaan kegiatan KKN tersebut adalah, untuk mengamalkan salah satu dari Tri Dharma perguruan tinggi di Indonesia, yakni pengabdian di masyarakat. Adapun secara spesifik tujuan dari pelaksanaan kegiatan tesebut adalah membantu masyarakat di sana mencari dan menemukan solusi dari permasalahan yang di alamai oleh masyarakat. Agar tujuan tersebut dapat terwujud, diadakannya Program-program yang bisa membangun masyarakat kp. Bolang dalam bidang Ekonomi, Pendidikan, Agama dan Sosial guna untuk meningkatkan integritas masyarakat dan meningkatkan
MOTIVATING STUDENTS TO SPEAK THROUGH CONTEXTUAL TEACHING LEARNING
Authors: Shabir Muhammad
Published: December 2020

This study investigated students‟ motivation in speaking through Contextual Teaching Learning (CTL) at a junior high school in Bogor, West Java. The procedures of action research: plan, act, observe, reflect, and revise were used to investigate the participants‟ learning activities and motivation. The study was conducted in two cycles involving two on-site English teachers. Data were collected through the teacher’s journal, observers‟ sheets, students‟ diaries, and questionnaires. The results of the research indicated that students‟ motivation in speaking could be improved through exposure to a variety of learning activities that connect the learning activities to the students‟ lives and experiences. Finally, the results of the study are expected to have a contribution to developing students to be motivated language learners.
TEACHERS’ PERSPECTIVES TOWARD SUCCESSFULNESS OF ENGLISH LANGUAGE TEACHING TO YOUNG LEARNERS
Authors: Nurazizah Siti , Rachmawati Nur Maulidia
Published: December 2020

In response to the need of qualified teaching English in primary level, successful English teaching has become a crucial and challenging issue. This exploratory case study examines the perspectives of teachers regarding successful English language teaching for young learners. Data of this study was collected from multiple interviews with seven English teachers teaching in five Islamic Integrated Elementary Schools in Bogor that offer English as an additional language (EAL). The findings reveal that the participants of this study had relatively the same understanding or perspectives on teaching English for young learners on eight criteria among the nine criteria of successful English language teaching to young learners. It was also found that five criteria had 100% agreement and were in line with the theories of successful teaching English to young learners. There was one criterion that had 57% inlined result. There were three inlined criteria which were relatively the same amount with 86%. Therefore, the other criterion was not in accordance with the seven respondents with 0% agreement.
СТРАТЕГІЯ УПРАВЛІННЯ КОНКУРЕНТОСПРОМОЖНІСТЮ АГРАРНИХ ПІДПРИЄМСТВ
Authors: Боровік Л.В.
Published: December 2020

Управління конкурентоспроможністю аграрних підприємств є надзвичайно складним завданням, оскільки їхня господарська діяльність перебуває під впливом багатьох чинників, які діють за певних умов із різною інтенсивністю і характеризуються багатовекторністю. Найважливішими чинниками конкурентних переваг аграрних підприємств у регіоні є: ресурсний потенціал; фінансове становище; кон'юнктура на ринку сільськогосподарської продукції; інноваційно-інвестиційний, технічний, технологічний, інфраструктурний, кадровий та соціальний потенціал. Організаційно-економічний механізм підвищення конкурентоспроможності аграрних підприємств повинен включати такі заходи державної підтримки: науково-технічну та інноваційно-технологічну політику; інвестиційну, цінову, податкову, фінансово-кредитну, зовнішньоекономічну, антимонопольну, антикримінногену, антикорупційну політику. Держава повинна на законодавчому рівні підтримувати розвиток інтеграційних процесів, сприяти відновленню зрошуваної та дренажної систем у регіоні, здійснювати контроль над використанням земельних і водних ресурсів.
Visual triggers of skin picking episodes: An experimental study in self-reported skin picking disorder and atopic dermatitis
Authors: Mehrmann Linda Marlen , Urban Alice , Gerlach Alexander Leopold
Published: December 2020

Background

Skin Picking Disorder (SPD) is a new diagnosis with limited information available about triggers of picking episodes. Itch can be induced via audio-visual stimuli and the effect of contagious itch is stronger for those affected by atopic dermatitis. We examined if picking-related visual stimuli can trigger the urge to pick skin in self-reported SPD. We compared itch and the urge to pick in a sample of AD and/or SPD-affected to controls without either.

Method

Urge to pick skin and/or scratch when viewing 24 itch-related, picking-related or neutral online pictures was assessed in adult females, who self-report skin-picking (SPD-only, n = 147) and/or atopic dermatitis (AD-only, n = 47; AD+SPD, n = 46) as well as in skin healthy controls (HC, n = 361).

Results

All participants reported a stronger urge to pick for picking-related pictures compared to neutral content (F[1, 597] = 533.96, p < .001, ηp2 = .472) and more itch for itch-related pictures compared to neutral stimuli (F[1, 597] = 518.73, p < .001, ηp2 = .465). SPD-all (SPD-only & AD+SPD) reported stronger urges to pick for picking-related vs. other stimuli compared to the AD-only and HC group (p < .001, ηp2 = .047). Likewise, AD-all (AD-only & AD+SPD) reported significantly stronger itching for itch-related vs. other stimuli compared to SPD-only and HC (p = .001, ηp2 = .019).

Conclusions

Analog to visual provocation of itch, the urge to pick can be triggered by visual stimuli. Treatments for SPD and AD may profit from addressing visual stimuli.
Best Practices for the Conservation and Preservation of Herbaria
Authors: Bromberg Leora
Published: December 2020

This paper offers an in-depth report on the best practices for the conservation and preservation of herbaria within library and museum collections. A herbarium (singular) is a collection of dried and pressed plant specimens, typically mounted onto paper and accompanied by a certain degree of recorded information. These organic specimens tend to be housed in museums or special collections libraries, where their handling can be carefully monitored and/or restricted. Each herbarium is typically one-of-a-kind and may serve as a vital primary source on human exploration, taxonomy, natural history and even amateur collection practices. A closer look at the best practices for their conservation and preservation spotlights the herbarium as a fragile, valuable and perhaps an unexpected or unusual form of “recorded information” that librarians, archivists and museum professionals may encounter or even have some responsibility over at some point in their careers.
浅谈预应力混凝土箱梁张拉技术
Authors: 房 瑞霞
Published: December 2020

数控智能张拉设备是目前高架桥现浇简支梁、连续梁、连续刚构预应力筋进行张拉的新型设备，施工现场具备经批准的张拉程序和现场施工说明书，张拉应力控制符合设计要求，张拉期间，千斤顶的张拉作用线与轴线相重合，同时以伸长值进行校核，实际伸长值与理论伸长值的差值控制在±6%以内。经过简支梁底板、腹板、顶板分阶段施加预应力实验数据，得出不同断面的伸长量，因此对比传统张拉技术，智能张拉技术同步精确率较高。
Los medios sociales y su influencia en la decisión de compra de la generación millennial
Authors: Barros Evelyn , Landa Carmen , Villalba Raúl
Published: December 2020

El social media en los últimos años ha tomado una mayor presencia en el ámbito social y empresarial, debido a que la generación millennial representa un gran porcentaje de la población y se encuentra inmersa en los distintos medios sociales. Razón por la cual se generan estrategias que ayudan a promocionar a los productos o servicios para lograr influir en el consumidor a la hora de tomar una decisión de compra. El objetivo de la investigación fue analizar la influencia que tiene el social media en el proceso de decisión de compra en la generación millennial. Contó con un método cualitativo que ayudo a estructurar el instrumento de recolección de datos. El método cuantitativo se aplicó para el diseño y aplicación del instrumento igualmente, en el análisis e interpretación de la información de los datos recolectados a través de la encuesta aplicada. La investigación tuvo un alcance correlacional, ya que se calculó el nivel de influencia, la relación de social media y la decisión de compra. La muestra de estudio fue de trescientas ochenta y dos (382) personas de la generación millennial. El principal resultado obtenido fue el impacto que tienen las redes sociales frente a la decisión de compra: Facebook es la red social con mayor interacción en tiendas virtuales por lo que el “usuario” es el protagonista principal dejándose influenciar por los comentarios y opiniones que se generan en esta red. Se concluyó que las estrategias de promoción influyen en la decisión de compra, ya que son estrategias interactivas dado que permiten crear un vínculo con el consumidor, de manera que a través de ellas las empresas aprovechan para llamar la atención de sus clientes.
Organik düzenleyici uygulanmış toprakta erozyonla oluşacak toprak kaybının tahmini
Authors: ÖZTÜRK Elif , ÖZDEMİR Nutullah
Published: December 2020

Toprak karmaşık süreçler sonucunda oluşan, yeryüzündeki madde döngülerinin gerçekleştiği, canlı ve kompleks bir ekosistemdir. Yaşamın temelini oluşturan bu kompleks sistem erozyonla kaybolmaktadır. Bu çalışma, yapay yağış koşullarında oluşan toprak kaybı değerleri ile erozyona karşı duyarlılığın değerlendirilmesinde kullanılan parametreler ve bazı fiziko-kimyasal toprak özellikleri arasındaki ilişkileri belirlemek ve bu özellikleri kullanarak erozyonla oluşabilecek toprak kaybı değerinin tahmin edilmesini sağlayacak bir model geliştirmek üzere yürütülmüştür. Çalışmada Samsun ili sınırları içerisinde bulunan Minoz Havzası’nda yayılım gösteren Lithic Ustorthent ve Typic Calciustept olarak sınıflandırılan topraklar ile çöp kompostu, çeltik kavuzu kompostu ve ahır gübresi düzenleyicileri kullanılmıştır. Havzaya ait bozulmuş toprak örneklerine organik düzenleyiciler kuru ağırlık esasına göre farklı dozlarda (% 0, 2, 4 ve 6) uygulanarak simulasyon uygulaması yapılmış ve kalite parametrelerinin belirlenebilmesi amacıyla deneme kurulmuştur. Denemeler sonucunda, topraklara uygulanan organik düzenleyicilerin toprak-su kayıplarını azalttığı ve erozyona karşı dayanıklılığı artırdığı belirlenmiştir. Toprak kayıplarının daha az olarak tespit edildiği uygulamalarda kalite parametreleri diğer uygulamalara kıyasla daha yüksek değerler almıştır. Yapay yağış koşullarında ölçülen ve geliştirilen pedotransfer fonksiyonlar (PTFs) ile tahmin edilen toprak kaybı değerlerinin karşılaştırılmasında determinasyon katsayısı (R2) kullanılmıştır. Havzada toprak kaybını tahmin etmek için kullanılacak eşitliğin R2 değeri 0.95 olarak elde edilmiştir. Bu sonuçlar geliştirilen pedotransfer eşitliklerin Minoz Havzası topraklarında gerçekleşen kayıpların tahmin edilmesinde kullanılabileceğini göstermiştir.
İNGİLTERE’DE KURULAN DARDANEL KOMİSYON’UN ÇANAKKALE SAVAŞI İLE İLGİLİ SORULARINA OSMANLI İMPARATORLUĞU’NUN VERDİĞİ CEVAPLAR
Authors: KARATAŞ Murat , ÖZYİĞİT Suat Eren
Published: December 2020

1916 tarihli “Özel Komisyonlar Yasası”na dayanarak Çanakkale Cephesi’ndeki başarısızlık nedenlerini araştırmak üzere İngiltere’de “Dardanelles Commission” kurulmuştu. Bu komisyon, Kraliyet Soruşturma Komisyonları’ndan biri idi. 10 kişiden oluşan bu komisyonunun başkanlığına 75 yaşındaki Evelyn Baring atanmıştı; ancak Baring 29 Ocak 1917 tarihinde ölünce komisyonun başkanlığına Yüksek Mahkeme Hâkimi William Pickford getirildi.

Henüz Birinci Dünya Savaşı bitmeden kurulan bu komisyon, tahliye ile neticelenen “Gelibolu Harekatı”ndaki kayıpların nedenlerini ve sonuçlarını araştıracaktı. Mahkeme gerekli görürse tanık ifadelerine de başvurabilirdi. Bu amaçla 1916 yılı ağustos ayından 1917 yılının eylül ayına kadar 168 tanığın ifadesi mahkemede dinlendi. Çanakkale Komisyonu, 1917 yılının şubat ayında ve aralık ayında iki ayrı rapor yayınlamıştı. Komisyonun kuruluş amacı, büyük oranda Hamilton ile Winston Churchill’in harekâttaki ihmallerini sorgulama hedefine matuf iken ortaya çıkan tablo, Gelibolu Harekâtı’nın İngiltere açısından başarılı olduğu şeklindeki kanaatin ağır basmasına vesile oldu.

Askeri arşiv çalışmaları esnasında rastladığımız bir belge dizini, İngiltere’de kurulan bu komisyonun Osmanlı Devleti ile de iletişime geçtiğini ortaya çıkardı. Bu makale, İngiltere’de kurulan Çanakkale Komisyonu’nun Çanakkale Savaşları ile ilgili Osmanlı Devleti’ne neler sorduğunu ve ondan ne cevaplar aldığını ele almaktadır.
A LITERATURE REVIEW ON GENITAL SELF IMAGE IN WOMEN AND AFFECTING FACTORS
Authors: DOĞAN YÜKSEKOL Özlem , YILMAZ Ayşe Nur , İRTEGÜN Sinan
Published: December 2020

Abstract
The genital self-image, which is an important factor for women's health, has been defined as the self-attitude and the following emotion arising directly or indirectly from special interactions and experiences involving the genital organs. Women's beliefs and feelings about their genital organs are expressed as a sensitive subject because they are seen as secret and taboo. But nowadays many women find the appearance of their genital organs very important and are more interested in appearance. Although both women and men report negative genital self-images, research has shown that men tend to have a more positive genital self-image than women. Genital self image; body image, organ loss, sexual functions, genital hygiene practices, vaginal infections, culture, obesity, developmental periods and media. When we look at the literature, body image studies mostly focused on women's attitudes towards beauty, weight, and skin color, leaving the issue of genital self-image in the background. In fact, genital self-image plays an important role in the development of sexual health and body image. Recently, it has been found that women have an increasing desire to undergo genital cosmetic / plastic surgery operations and change the appearance and functions of their vulva and vagina due to their negative views on their genital self-image. It is important to examine all the factors that affect the genital self-image, which is of great importance for women's health, and to provide the necessary care by taking a holistic approach in terms of body perception and sexuality. Nurses / midwives should adopt approaches to increase the body and genital image of women and to increase the quality of life of individuals. Nurses / Midwives are healthcare professionals in the most appropriate position to provide the necessary support in developing a new genital self-image and positive lifestyle.
THE EUROPEAN UNION, CHINA AND SOLAR PANEL
Authors: Innocenthia Adieuva , Margaretha Yosinta , One Febri , Christine Junita , Magdalena Agnes
Published: December 2020

The European Union and China are the two countries that have advantages in each of them. The European Union and China have a dispute regarding renewable energies, namely the problem with solar panels. China's policy of making solar panels prices have low bargaining power makes the European Union unable to accept the policy because it can cause a long trade conflict. The case study in this paper also illustrates that the EU is actively approaching it to overcome environmental challenges in China by involving the European Union in dialogue and negotiation on various issues and providing capacity-building support. China also introduced trade reforms and carbon emissions to environmental decision-making bodies in the European Union, and it was supported by the European Union, including through meetings to determine sustainable policies and development projects on energy and the environment.

 

Keywords: EU – China dispute, Environmental Challenges, anti-dumping, China’s policy, World Trade Organization.
INDONESIA SOFT POWER: TOBA CALDERA AS UNESCO GLOBAL GEOPARK 2020
Authors: Manurung Hendra , Sinabariba Elvinro
Published: December 2020

This research aims to describe analytically Toba Caldera's ability to become one of the UNESCO Global Geopark in 2020. The research used a qualitative research method and is done through literature studies, government documents, and internet sources. Researchers founded, there are inter-linkages amongst Indonesia's central and local government together with stakeholders' continuous contribution who concern with Toba Caldera's sustainable tourism development. Those concerning parties fought for Toba Caldera's recognition status as the UNESCO Global Geopark.  From 2011 to 2020, for nine years, the Toba Caldera was finally named a UNESCO Global Geopark during the UN Cultural Body's 209th Plenary Session held in Paris on July 7, 2020.  Toba Caldera Geopark was a worldwide tourist magnet as it was home to 13 sites with breathtaking views, namely: Tongging Sipiso-Piso, Silalahi Sabungan, Haranggaol, Sibaganding Parapat, Eden Park, Balige Liong Spige Meat, Situmurun Blok Uluan, Hutaginjang, Muara Sibandang, Sipinsur Bakti Raja, Bakara Tipang, Tele Pangururan, and Pusuk Buhit. A ceremony where the UNESCO Global Geopark placard will be formally given to the Toba caldera is slated to be held in Jeju, South Korea, by September 2020. According to a statement from the Indonesian Embassy in Paris, Toba Caldera is among the 16 new UNESCO Global Geoparks announced by the organization's executive board. North Sumatra provincial administration is hopeful that the recognition will help boost foreign tourist arrivals to the destination.

Keywords: Toba caldera, UNESCO, Indonesia soft power, sustainable tourism development, tourist destination
The Behavior of Using Online System of Public Aspirations and Complaints Service (LAPOR) in Mataram City
Authors: Iqbal Muhammad , Virginia Cindy Yulita
Published: December 2020

Public Complaint and Aspiration Service (LAPOR!) was initially a program spearheaded by the Presidential Work Unit for Development Supervision and Control (UK4). This program is associated with the administration of public services by all government agencies. Furthermore, it is used by the Mataram City Government as a medium to facilitate public aspirations and complaints. Therefore, this research aims to comprehend the factors influencing the community in applying the LAPOR! Application in the Mataram city in 2019. This is a mixed method research with data obtained from 70 user communities through interviews with related agencies and by distributing questionnaires, with the PLS and SPSS applications used for analysis. The results showed that the variable performance expectancy, effort expectancy, and social influence significantly affect behavioral intention. Meanwhile, facilitating condition and behavioral intention has a positive and significant impact on the utilization of LAPOR! Application. These were indicated by the P-value <0.005 and the T statistical value> 1.96, thereby concluding that each hypothesis proposed in this study is accepted.
Ungas psykiska ohälsa i medicinsk media 1970-2017
Authors: Larsson Anna-Karin
Published: December 2020

Den här artikeln handlar om synen på barns och ungas psykiska hälsa och bygger på en studie av diskussioner, information och kunskap om ungas psykiska hälsa i Läkartidningen under 1970-, 1990- och 2010-talen. Syftet med studien har varit att undersöka hur den psykiska ohälsan och psykosociala problem har förklarats, om frågor, problem och förklaringar har förändrats över tid samt hur flickors och pojkars ohälsa framställts. Ambitionen med studien har varit att nå en fördjupad kunskap om hur den medicinska kunskapen relaterat till den historiska kontexten och interagerat med andra politiska och samhälleliga diskurser. 

Bilden som framträder präglas av både kontinuitet och förändring. Det finns under perioden en genomgående och stabil uppfattning om dels en pågående ökning av psykiska besvär och psykosociala problem, dels en större utsatthet hos flickor. Det som förändras i den medicinska diskursen är framförallt vilka ohälsoproblem som tas upp samt förklaringarna till dem. Under 1970-talet finns en föreställning om att flickor är mer labila än pojkar och biologiska förklaringar till ohälsan förekommer. Gruppen barn och unga är förhållandevis homogen i texterna under 1970-talet. Ungdomar blir längre fram under undersökningsperioden en alltmer heterogen grupp med skilda ohälsouttryck, behov och utsikter. Medan man i de tidiga texterna beskriver hur ungas psykiska ohälsa ökar, oroas man i de senare decenniernas texter över att flickors psykiska ohälsa ökar. Ytterligare en förändring över tid är ohälsans uttryck i nya diagnoser, beteenden och symtom. Medan ohälsan under 1970-talet beskrivs i form av depressioner, huvudvärk och självdestruktivt beteende som kriminalitet och narkotika- eller alkoholmissbruk, observeras och beskrivs i högre utsträckning stressrelaterade problem med psykosomatiska uttryck från 1990-talet och framåt. En tydlig förändring är den nya uppmärksamheten kring levnadsvanornas betydelse för den psykosociala ohälsan. Nya och oroande levnadsvanor som stillasittande, skräpmat och tv/dataspelstid avslöjar också en utveckling och förändring av ungdomars fritidsvanor.
Sysselsättning för unga med intellektuell funktionsnedsättning
Authors: Arvidsson Jessica , Staland-Nyman Carin , Wildén Stephen , Tideman Magnus
Published: December 2020

Studien analyserar sambanden mellan sysselsättning för unga vuxna med intellektuell funktionsnedsättning som gått i gymnasiesärskolan och deras sociala bakgrund, mätt som föräldrarnas utbildningsnivå och geografiska härkomst. 

  Den här registerstudien baseras på Halmstad university register on pupils with intellectual disabilities (HURPID), Longitudinell integrationsdatabas för arbetsmarknads- och sjukförsäkringsstudier (LISA) samt LSS-registret. Studien omfattar 12 269 unga med intellektuell funktionsnedsättning som gick ut gymnasiesärskolan mellan 2001 och 2011. De samband som studeras analyseras genom multipla logistiska regressioner. 

  Resultaten visar att föräldrars utbildningsnivå har viss betydelse för före detta gymnasiesärskoleelevers sysselsättning. Barn till högutbildade föräldrar har med större sannolikhet en sysselsättning inom daglig verksamhet och barn till lågutbildade föräldrar har med större sannolikhet ett förvärvsarbete. Sannolikheten för att ha någon av sysselsättningskategorierna daglig verksamhet eller förvärvsarbete är lägst bland barn till föräldrar som är födda i länder utanför Norden. Högutbildade föräldrar antas ha en högre grad av den ”välfärdskompetens” som krävs för att hantera dagens välfärdssystem och härigenom kunna påverka de ungas möjligheter att få insatser likt daglig verksamhet. Lågutbildade föräldrar antas ha egna erfarenheter av, och kontakter med, arbetsplatser där det finns arbetsuppgifter utan (eller med låga) formella kompetenskrav.  

  Samhällets kunskaper och medvetenhet om den sociala bakgrundens betydelse för efter(sär)gymnasial sysselsättning bland unga med intellektuell funktionsnedsättning behöver öka. Detta i syfte att bättre möta varierande individuella förutsättningar och främja etablering i arbetslivet för fler unga vuxna med intellektuell funktionsnedsättning vid övergången från skoltid till arbetsliv.
Development and Validation of a Combined Ferroptosis and Immune Prognostic Classifier for Hepatocellular Carcinoma
Authors: Liu Yang , Zhang Xi , Zhang Junjun , Tan Juan , Li Jie , Song Zewen
Published: December 2020

Background

Immunotherapy and sorafenib exert anti-tumor effects via ferroptosis, but reliable biomarkers for the individual treatment and prognosis prediction of hepatocellular carcinoma (HCC) based on the ferroptosis and immune status remain lacking.

Methods

Ferroptosis-related genes (FRGs) were identified by downloading data from FerrDb and by searching and reading original articles from PubMed. Immune-related genes (IRGs) were downloaded from ImmPort. Prognostic FRGs and IRGs in the GSE14520 (n = 220) and The Cancer Genome Atlas (TCGA, n = 365) datasets were identified. Least absolute shrinkage and selection operator (LASSO) Cox regression and multivariate Cox regression were used for model construction. Ferroptosis expression profiles, the infiltration of immune cells, and the somatic mutation status were analyzed and compared.

Results

Twenty-seven prognostic ferroptosis- and immune-related signatures were included to construct a comprehensive index of ferroptosis and immune status (CIFI). A subgroup of patients was identified as having a high CIFI value, which was associated with a worse prognosis. This subgroup of patients had significantly up-regulated expressions of many suppressors of ferroptosis and higher fractions of immunosuppressive cells, such as cancer-associated fibroblasts (CAFs) and myeloid-derived suppressor cells (MDSCs). Notably, somatic mutation analysis indicated that high-CIFI patients had higher levels of tumor heterogeneity and higher mutation frequencies of genes like TP53.

Conclusion

In this work, a novel prognostic classifier was developed based on ferroptosis- and IRGs in HCC, and this classifier could be used for prognostic prediction and the selection of patients for immunotherapies and targeted therapies.
Mitochondrial Membrane Intracellular Communication in Healthy and Diseased Myocardium
Authors: Kumar Vishnu K. , Lackey Atreju , Snyder Jonathan , Karhadkar Sunil , Rao Ajay D. , DiCarlo Antonio , Sato Priscila Y.
Published: December 2020

Research efforts in the twenty-first century have been paramount to the discovery and development of novel pharmacological treatments in a variety of diseases resulting in improved life expectancy. Yet, cardiac disease remains a leading cause of morbidity and mortality worldwide. Over time, there has been an expansion in conditions such as atrial fibrillation (AF) and heart failure (HF). Although past research has elucidated specific pathways that participate in the development of distinct cardiac pathologies, the exact mechanisms of action leading to disease remain to be fully characterized. Protein turnover and cellular bioenergetics are integral components of cardiac diseases, highlighting the importance of mitochondria and endoplasmic reticulum (ER) in driving cellular homeostasis. More specifically, the interactions between mitochondria and ER are crucial to calcium signaling, apoptosis induction, autophagy, and lipid biosynthesis. Here, we summarize mitochondrial and ER functions and physical interactions in healthy physiological states. We then transition to perturbations that occur in response to pathophysiological challenges and how this alters mitochondrial–ER and other intracellular organelle interactions. Finally, we discuss lifestyle interventions and innovative therapeutic targets that may be used to restore beneficial mitochondrial and ER interactions, thereby improving cardiac function.
Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington's Disease
Authors: Czeredys Magdalena
Published: December 2020

Huntington's disease (HD) is a progressive neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric problems. It is caused by a polyglutamine expansion in the huntingtin protein that leads to striatal degeneration via the transcriptional dysregulation of several genes, including genes that are involved in the calcium (Ca2+) signalosome. Recent research has shown that one of the major Ca2+signaling pathways, store-operated Ca2+entry (SOCE), is significantly elevated in HD. SOCE refers to Ca2+flow into cells in response to the depletion of endoplasmic reticulum Ca2+stores. The dysregulation of Ca2+homeostasis is postulated to be a cause of HD progression because the SOCE pathway is indirectly and abnormally activated by mutant huntingtin (HTT) in γ-aminobutyric acid (GABA)ergic medium spiny neurons (MSNs) from the striatum in HD models before the first symptoms of the disease appear. The present review summarizes recent studies that revealed a relationship between HD pathology and elevations of SOCE in different models of HD, including YAC128 mice (a transgenic model of HD), cellular HD models, and induced pluripotent stem cell (iPSC)-based GABAergic medium spiny neurons (MSNs) that are obtained from adult HD patient fibroblasts. SOCE in MSNs was shown to be mediated by currents through at least two different channel groups, Ca2+release-activated Ca2+current (ICRAC) and store-operated Ca2+current (ISOC), which are composed of stromal interaction molecule (STIM) proteins and Orai or transient receptor potential channel (TRPC) channels. Their role under physiological and pathological conditions in HD are discussed. The role of Huntingtin-associated protein 1 isoform A in elevations of SOCE in HD MSNs and potential compounds that may stabilize elevations of SOCE in HD are also summarized. Evidence is presented that shows that the dysregulation of molecular components of SOCE or pathways upstream of SOCE in HD MSN neurons is a hallmark of HD, and these changes could lead to HD pathology, making them potential therapeutic targets.