bluuebunny/crossref_metadata_2025 huggingface dataset:
Enzalutamide in the treatment of metastatic castrate-sensitive prostate cancer
Authors: Meade Elizabeth
Published: February 2023

The treatment landscape for metastatic castrate-sensitive prostate cancer has changed dramatically in the past decade because of the approval of chemotherapy and novel androgen therapies in combination with androgen deprivation therapy. The addition of these agents has resulted in overall benefits and progression-free survival for patients. The National Institute for Health and Care Excellence recently approved enzalutamide in the treatment of metastatic castrate-sensitive prostate cancer. Oncology nurse prescribers are central to the care of prostate cancer, providing holistic assessment and management of the disease and treatment side effects. A comprehensive understanding of the mechanism of action and specific side effects of androgen receptor inhibitors will enable an oncology nurse to provide timely interventions with a high standard of care.
Bespoke Circuits
Authors: Scheffels Gerald
Published: February 2023

BUILDING ONE-OFF ELECTRICAL SYSTEMS FOR MOBILE MACHINERY IS NO LONGER A PAINSTAKING DESIGN PROCESS, REQUIRING HOURS OF SWEAT AN TOIL - NOW THE LATEST ELECTRONIC COMPUTER-AIDED DESIGN (ECAD) SYSTEMS MEAN IT'S ALMOST AS SIMPLE AS SELECTING THE DESIRED CHARACTERISTICS, AND LETTING AUTOMATION DO THE REST
The Rock Star
Authors: Wordsworth Saul
Published: February 2023

JOHN DEERE'S NEW 8RX TRACTOR IS SO LIGHT ON ITS FEET THAT IT IMPROVES SOIL / QUALITY, THEREBY INCREASING YIELDS
Beating the competition
Authors: Sánchez José R.
Published: February 2023

A LEADING HYDRAULIC AND ELECTRONIC SYSTEMS MANUFACTURER OFFERS FIVE WAYS TO OPTIMISE WORK FUNCTION PERFORMANCE ON A COMPACT WHEEL LOADER
Complete Control Systems, Not Complex
Authors: Bromley Cody
Published: February 2023

A NEW MACHINE CONTROLLER PLATFORM FOR OEMs SIMPLIFIES SYSTEM DESIGN AND SPEEDS UP TIME TO MARKET
Heightened Functionality
Authors: Steadman Shelley
Published: February 2023

INTELLIGENT VEHICLE CONTROL IS MADE EASY WITH AMETEK VEHICULAR INFORMATION SYSTEMS' NEW USER DEFINABLE CONTROL MODULE
The Right Hose
Authors: Wilde Ralf
Published: February 2023

KINK-RESISTANT HOSES WITH NEAR-ZERO PERMEATION AND BROAD TEMPERATURE RANGES PROMISE TO KEEP VEHICLE AIR-CONDITIONING IN SERVICE FOR LONGER
Ready for Autonomy?
Authors: Harry Rachelle
Published: February 2023

TWO INDUSTRY EXPERTS REVEAL HOW LONG THEY BELIEVE IT WILL TAKE FOR FULL AUTONOMY TO BE ACHIEVED IN INDUSTRIAL VEHICLES - AND WHY
Magic Touch
Authors: Roper Jack
Published: February 2023

AS THE TREND FOR TOUCHSCREENS IN OFF-HIGHWAY VEHICLE CABINS GATHERS PACE, SO THE ARGUMENTS FOR MAKING HMI MORE INTUITIVE AND STANDARIZED ACROSS VEHICLE TYPES - AND EVEN BRANDS - BECOME MORE COMPELLING. SOME KEY CONCEPTS ARE NOW POINTING THE WAY AHEAD
Perfect Balance
Authors: Allen James , Stone Tom
Published: February 2023

ADVANCED OPERATOR ASSISTANCE SYSTEMS AND SMART DESIGN MAKE THE HX220A L FROM HYUNDAI A STRONG NEW CONTENDER IN THE POPULAR 19-24 TON CRAWLER EXCAVATOR MARKET
Multifunctional Ergonomics
Authors: Howe Christian
Published: February 2023

COMPONENTS AND SUBSYSTEMS USED IN OFF-HIGHWAY VEHICLES MUST BE ROBUST, USER-FRIENDLY AND VERSATILE
Displaying Variety
Authors: Solecki Rossella
Published: February 2023

DISPLAYS FROM A MARKET LEADER HAVE BEEN A FEATURE OF INDUSTRIAL VEHICLES FOR DECADES, OFFERING STATE-OF-THE-ART VISUALISATION AND VALUE
Analysis of Transmission Characteristics of EBG Structures by Subgridding Unconditionally Stable FETD Method
Authors: Wang Yixin , Wei Bing , Fan Kaihang
Published: February 2023

Subgridding unconditionally-stable finite-element time-domain method based on spatial modes filtering (SSMF-FETD) is combined with the Floquet theorem and used to analyze the transmission characteristics of 2-D dielectric pillar-array electromagnetic bandgap (EBG) structures with cross-section shapes of square and H. The computational stress is effectively reduced by exploiting the periodicity of the EBG structure and subgridding technique. Through the spatial modes filtering (SMF) method, the subgridding FETD (S-FETD) method is developed into the SSMF-FETD with larger time steps and higher computational efficiency. The effect of geometric and electromagnetic parameters on transmission characteristics of EBG structures are analyzed and compared in detail, the conclusions are as follows: the optimal filling ratio of the dielectric square-pillar EBG structure is 0.5, the composite H-pillar EBG structure has multiple bandgaps and can effectively save metal materials while satisfying the design requirements. The effect of electromagnetic parameters can be uniformly analyzed from the perspective of the average relative permittivity; with its increase, the central frequency of the bandgap becomes lower. It should be noted that the bandgap distribution and variation of composite H-pillar EBG structure are related to how its dielectric parameters change and combine. The results can serve as a reference for similar structures design.
Design of a Wideband CPW Fed Fractal Antenna for Satellite Communication
Authors: Nanthagopal Varnikha , Paramasivam Jothilakshmi
Published: February 2023

A novel ‘T’ square wideband fractal antenna is proposed for satellite communication. The Wideband is achieved through the ‘T’ square fractal design and CPW feed. At first, a conventional square-shaped patch antenna is designed. Then the square-shaped patch is replaced by a Type-I fractal to achieve wideband. Finally, a Type-II fractal with an L-Shaped boundary is used to enhance the bandwidth to a greater extent. The gain of the proposed antenna ranges from 4 dB to 6.3 dB for the entire frequency range of 6.2 GHz to 14 GHz. The radiation efficiency of the antenna is noticed up to 84%. The fractal antenna resonates well throughout the entire frequency range with a VSWR of less than 2. The antenna having such a wide band characteristic can be found suitable for a wide range of applications like earth exploration satellites, fixed satellites, radiolocation, maritime radio navigation, and aeronautical radio navigation. A metal reflector is also introduced at the bottom of the antenna to produce a unidirectional radiation pattern. This increases the gain up to 9.8 dBi and a front-to-back ratio is noticed above 20 dB. The design is fabricated and the measurement results are found to be in good agreement with the simulation results.
Bandwidth Enhancement of Slot Antenna Using Fractal Shaped Isosceles for UWB Applications
Authors: Aissaoui Djelloul , Chaabane Abdelhalim , Boukli-Hacene Noureddine , Denidni Tayeb A.
Published: February 2023

In this paper, a coplanar waveguide (CPW) fed slot antenna using fractal-shaped isosceles trapezoidal corrugations is designed and presented for Ultra-Wideband (UWB) applications. The proposed antenna is formed by a regular hexagonal patch fed through a CPW feed line and radiates amidst a notched wide hexagonal slot. The edge of the wide slot is shaped by a fractal structure that is formed by five trapezoidal notches. The antenna is printed on RO4350B substrate having a compact size of 0.305λ0 × 0.313λ0 × 0.012λ0 at 2.35 GHz. . Good agreement is registered between the experimental results of the fabricated prototype and the calculated ones. By using an Agilent 8722ES vector network analyzer, the fabricated prototype confirms that the antenna has an excellent matching impedance over the bandwidth 2.35-10.65 GHz (127%) which covers the entire UWB band. Furthermore, good radiation performances are measured in an anechoic chamber. Consistent radiation patterns with a reasonable peak gain are measured over the entire working bandwidth. Therefore, the designed structure may be worthily considered for different wireless communications systems.
Dual-channel graphene-based optical metasurface switch at telecommunication wavelengths
Authors: Kumari Rashmi , Sharma Shubhanshi , Varshney Shailendra Kumar , Lahiri Basudev
Published: February 2023

We theoretically present the concept of a dual-channel optical metasurface switch operating at telecommunication wavelengths. The switching exploits two Fano resonant peaks produced by two pairs of asymmetric silicon nano-bars stacked vertically with each pair acting as optical resonators. We have explored two types of asymmetricity in silicon nano-bars, viz., asymmetry in width and length. The Fano resonances of these silicon nano-bars could be tuned independently between “ON” and “OFF” states by changing the Fermi potential (E
f
) of the graphene sheet placed beneath each optical resonator. Transmission greater than 55% refers to the switch in the ON state, and less than 55% refers to the switch in the OFF state. We also demonstrate four possible combinations for both dual-channel switches, viz., ON–ON, ON–OFF, OFF–ON, OFF–OFF, for both types of optical resonators depending on the potential applied to the corresponding graphene sheet. Therefore, we have shown that any type of asymmetricity of nano-bars could be used to produce the dual-channel selective switch without compromising the performance. Further, we have shown the effect of varying parameters—asymmetry, intermediate thickness, graphene thickness, and temperature—on both resonances and the biasing arrangement by introducing another graphene layer in between.
Design of computer-generated holograms based on semi-rigorous simulations of sub-wavelength structures
Authors: Linß Sebastian , Zeitner Uwe D.
Published: February 2023

Conventional design methods for computer-generated holograms often rely on the scalar diffraction theory because the calculation effort of rigorous simulations is too high. But for sub-wavelength lateral feature sizes or large deflection angles, the performance of realized elements will show distinct deviations from the expected scalar behavior. We propose a new design method that overcomes this issue by incorporating high-speed semi-rigorous simulation techniques that allow the modeling of light propagation at an accuracy close to the rigorous methods. This includes an approach to solve the inverse problem of calculating a geometric structure that is able to form a certain physical field distribution.
Compressive space-dimensional dual-coded hyperspectral polarimeter (CSDHP) and interactive design method
Authors: Wang Jiayu , Shi Haodong , Liu Jianan , Li Yingchao , Fu Qiang , Wang Chao , Jiang Huilin
Published: February 2023

A compressive space-dimensional dual-coded hyperspectral polarimeter (CSDHP) and interactive design method are introduced. A digital micromirror device (DMD), a micro polarizer array detector (MPA), and a prism grating prism (PGP) are combined to achieve single-shot hyperspectral polarization imaging. The longitudinal chromatic aberration (LCA) and spectral smile of the system are both eliminated to guarantee the matching accuracy of DMD and MPA pixels. A 4D data cube with 100 channels and 3 Stocks parameters is reconstructed in the experiment. The feasibility and fidelity are verified from the image and spectral reconstruction evaluations. It is demonstrated that the target material can be distinguished by CSDHP.
Foundry manufacturing of tight-confinement, dispersion-engineered, ultralow-loss silicon nitride photonic integrated circuits
Authors: Ye Zhichao , Jia Haiyan , Huang Zhangjun , Shen Chen , Long Jinbao , Shi Baoqi , Luo Yi-Han , Gao Lan , Sun Wei , Guo Hairun , He Jijun , Liu Junqiu
Published: February 2023

The foundry development of integrated photonics has revolutionized today’s optical interconnect and datacenters. Over the last decade, we have witnessed the rising of silicon nitride (Si3N4) integrated photonics, which is currently transferring from laboratory research to foundry manufacturing. The development and transition are triggered by the ultimate need for low optical loss offered by Si3N4, which is beyond the reach of silicon and III-V semiconductors. Combined with modest Kerr nonlinearity, tight optical confinement, and dispersion engineering, Si3N4 has today become the leading platform for linear and Kerr nonlinear photonics, and it has enabled chip-scale lasers featuring ultralow noise on par with table-top fiber lasers. However, so far all the reported fabrication processes of tight-confinement, dispersion-engineered Si3N4 photonic integrated circuits (PICs) with optical loss down to few dB/m have only been developed on 4-inch (100 mm diameter) or smaller wafers. Yet, to transfer these processes to established CMOS foundries that typically operate 6-inch or even larger wafers, challenges remain. In this work, we demonstrate the first foundry-standard fabrication process of Si3N4 PICs with only 2.6 dB/m loss, thickness above 800 nm, and near 100% fabrication yield on 6-inch (150 mm diameter) wafers. Such thick and ultralow-loss Si3N4 PIC enables low-threshold generation of soliton frequency combs. Merging with advanced heterogeneous integration, active ultralow-loss Si3N4 integrated photonics could pave an avenue to addressing future demands in our increasingly information-driven society.
Associations between vigorous physical activity, social ties, social support, and self-reported health among older adults in Accra, Ghana
Authors: Asiamah Nestor , Kouveliotis Kyriakos , Eduafo Richard , Borkey Richard
Published: February 2023

Meeting recommended vigorous physical activity (VPA) levels represents a hallmark for healthy living, but VPA in older populations is likely to lead to casualties that may compel older adults to underscore their health. This study examined the associations between VPA, social ties, social support, and self-reported health in an African sample of older adults. This study adopted the cross-sectional design. The study population was community-dwelling older adults aged 60 years or higher in Accra, Ghana. A total of 686 older adults responded to self-reported questionnaires. Data were analysed with the Pearson’s chi-square test and binary logistic regression. The study found that older adults who had above 5 children were 3 times (AOR = 3.169; p = .002) more likely to participate in VPA for 30 minutes or more a day compared with their peers without children. Having social support from between 1 and 5 people was 28 times (AOR = 28.215; p = .000) more likely to result in good health compared to not having anyone to source social support from. Older adults who participated in VPA for 30 minutes or more were less likely (AOR = 0.129; p = 0.000) to report good health compared with those who participated in VPA for less than 30 minutes. We conclude that when social ties and other personal characteristics are adjusted for, prolonged VPA does not necessarily enhance self-reported health, and not all social ties contribute to VPA and self-reported health.
Determinants of depressive symptoms in older outpatients with cardiometabolic diseases in a Japanese frailty clinic: Importance of bidirectional association between depression and frailty
Authors: Yorikawa Fumino , Ishikawa Joji , Tamura Yoshiaki , Murao Yuji , Toba Ayumi , Harada Kazumasa , Araki Atsushi
Published: February 2023

Introduction

Frailty and depression may play important roles in the management of older patients with cardiometabolic diseases. We explored the determinants of depressive symptoms and their association with frailty among patients with cardiometabolic diseases (hypertension, diabetes, and atrial fibrillation) in a cross-sectional study.

Methods

A total of 633 outpatients aged 65 years or older with cardiometabolic disease and suspected symptoms of frailty participated in this study. Depressive symptoms, physical activity, and social network were assessed using the Geriatric Depression Scale (GDS)-15, International Physical Activity Questionnaire, and Lubben Social Network Scale-6 (LSNS-6), respectively. Frailty was evaluated using the Kihon Checklist (KCL) based on the Comprehensive Geriatric Assessment (CGA), the modified Cardiovascular Health Study (mCHS), and the Clinical Frailty Scale (CFS). Binomial logistic regression analysis was used to examine the determinants of depressive symptoms and their association with frailty.

Results

Depressive symptoms with GDS-15 scores ≥ 5 were present in 43.6% of the patients. In logistic regression, after adjusting for covariates, the determinants of depressive symptoms in all patients were lack of social network, low years of education, and frailty. In contrast, in logistic regression with frailty as the dependent variable, depressive symptoms were independently associated KCL-defined frailty (OR = 6.28, 95% CI: 4.13–9.55) and mCHS-defined frailty (OR = 2.66, 95% CI: 1.70–4.17), but not with CFS. Similarly, significant associations between depression and frailty were observed in patients with hypertension, diabetes, or atrial fibrillation.

Conclusions

Lack of social networks, low education, and frailty based on the KCL and mCHS were important determinants of depressive symptoms in all patients. The relatively strong associations between depressive symptoms and frailty based on CGA in patients with hypertension, diabetes, or atrial fibrillation suggest that the assessment of depressive symptoms is of great importance in clinical practice in those patients at high risk of frailty.
The relationship between weight history and psychological health—Differences related to gender and weight loss patterns
Authors: Jung Franziska U. C. E. , Riedel-Heller Steffi G. , Luck-Sikorski Claudia
Published: February 2023

Background

The prevalence and burden of obesity continues to grow worldwide. Psychological comorbidities may not only influence quality of life, but may also hinder successful weight loss. The causality between excess weight and mental health issues is still not fully understood. The aim of the study was to investigate whetherweight history parameters, (ie.age of onset) are related to psychological comorbidities.

Method

The data were derived from a representative telephone survey in Germany, collecting information on weight loss patterns and mental health outcomes among individuals with BMI>30kg/m2. Overall, 787 participants were examined in terms of depressive symptoms (Patient Health Questionnaire, PHQ-9) and anxiety (Generalized Anxiety Disorder Questionnaire, GAD7). In addition, participants were asked about different aspects of their weight history (ie. weight loss patterns and trajectories) over the lifespan. The relationship between weight history and mental health was analyzed using multivariate statistics.

Results

According to regression analyses, having had more weight loss attempts, a greater weight loss being desired and being a “weight maintainer” was associated with more symptoms of depression (p < 0.001), whereas a greater desired weight loss and being categorized as a “weight maintainer” was associated with more anxiety (p < 0.001). Moroever, the prevalence of depressive symptoms was significantly higher in male individuals who desire to lose more weight or had more weight loss attempts in the past.

Conclusion

Gender-specific differences were observed in terms of weight history parameters, as well as mental health outcomes. Especially for men, weight loss patterns seem to be related to depressive symptoms. Concerning the overall results, it becomes clear that screening for weight history at the beginning of a multidisciplinary weight loss program in the context of gender-specific psychological comorbidities is important. The question remains why some aspects of weight history seem to be more important than others.
Childhood and nature in the Iranian post-war film Willow and Wind (Talebi 1999)
Authors: Merás Lidia
Published: February 2023

Mohammad-Ali Talebi’s forgotten masterpiece Beed-o Baad (Willow and Wind) () is an Iranian children film written by Abbas Kiarostami, that pays tribute to the children of the post-war generation. As in other children’s films of the period, the young hero has a mission, which he stubbornly pursues. Set in a village in Northern Iran, the story follows the boy’s efforts to repair a broken glass during very stormy weather. This article will examine the visual motives of Willow and Wind (a boy climbing a hill, single trees, wind, rain) paying particular attention to the interaction with nature. The tree and the wind alluded to in the title underline the struggle and determination of Iranian children. In line with the children’s films produced by the Center for the Intellectual Development of Children and Young Adults (CIDCYA, aka Kanoon), it applauds the willpower of a generation with enormous responsibilities, while placing his protagonist as a role model for audiences of all ages. However, by rejecting the happy ending, the film opposes the predominant narrative model of Iranian educational films of the 1980s and 1990s while criticizing adults’ treatment of boys in post-revolutionary Iran. In this moral tale, Talebi stresses the dignity and resourcefulness of rural Iran but condemns the solitude of children, and the distance between the worlds of adults and children setting a precedent for future Iranian children’s films.
The German Cinema Book, 2nd ed., Tim Bergfelder, Erica Carter, Deniz Göktürk and Claudia Sandberg (Eds) (2020)
Authors: Ward Elizabeth M.
Published: February 2023

Review of: The German Cinema Book, 2nd ed., Tim Bergfelder, Erica Carter, Deniz Göktürk and Claudia Sandberg (Eds) (2020)

London: BFI, 604 pp.,

ISBN 978-1-84457-530-5, p/bk, £36.99
Bases doctrinales del control social del crimen y la violencia
Authors: Rojas Jiménez Andy , Roque Rodríguez Yanier Senén , Castellanos Fuentes Pedro Enrique
Published: February 2023

El control social proporciona una perspectiva compleja de las formas de lucha antidelictiva. El objetivo de la investigación es realizar una valoración histórica y teórico-doctrinal del control social y sus componentes, a través de un estudio crítico de la experiencia ecuatoriana en la lucha de la criminalidad, con vistas a su mejoramiento. Mediante un enfoque cualitativo y aplicando una revisión documental narrativa, se logra una aportación sistematizada de los instrumentos teórico-doctrinales imprescindibles para construir una teoría propia del proceso de control social de la criminalidad, contextualizada a la realidad ecuatoriana; concluyéndose la necesidad de reformular políticas efectivas de control social del crimen y la violencia en el país.
Validación de la escala de gravedad percibida de la violencia de pareja contra la mujer en población ecuatoriana
Authors:   Departamento de Psicología Social, Universidad de Valencia, España, Villagrán Aída M. , Martín-Fernández Manuel ,   Departamento de Psicología Social, Universidad de Valencia, España, Gracia Enrique ,   Departamento de Psicología Social, Universidad de Valencia, España, Lila Marisol ,   Departamento de Psicología Social, Universidad de Valencia, España
Published: February 2023

Introducción: La violencia de pareja contra la mujer (VPM) es un problema de salud pública a nivel global cuya prevalencia en Ecuador es de las más elevadas de Latinoamérica. La gravedad percibida de la VPM influye en las actitudes públicas hacia la VPM, como la aceptabilidad, el sentido de responsabilidad personal o la disposición a intervenir en casos de VPM. Método: En este estudio se presenta la adaptación de la escala española de gravedad percibida de la VPM (PS-IPVAW) al contexto cultural ecuatoriano, en una muestra de 652 participantes. Resultados: Los resultados mostraron que la escala PS-IPVAW tiene una buena consistencia interna, que sus ítems tienen una baja carga de deseabilidad social, que es invariante entre géneros y que se relaciona con la culpabilidad a la víctima, la aceptabilidad de la VPM yel sexismo hostil. Discusión: La escala PS-IPVAW es un instrumento con suficientes evidencias de fiabilidad y validez para evaluar la gravedad percibida de la VPM en Ecuador y representa un importante aporte para mejorar las estrategias de prevención, intervención y erradicación de este tipo de violencia en el contexto ecuatoriano.
A ESPACIALIZAÇÃO DA COVID-19 NO ESTADO DO MARANHÃO, BRASIL (2020-2021)
Authors: Costa Thiago Ronyerisson Silva , Santana Raquel Pereira , Sousa Igor Breno Barbosa de , Sodré Ronaldo Barros , Cunha Hermeneilce Wasti Aires Pereira , Mattos Junior José Sampaio de
Published: February 2023

A pandemia da Covid-19 teve origem a partir da nova Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), agente causador da doença denominada de Covid-19 (coronavirus disease 2019), que surge no final de 2019 na China, tendo seu primeiro caso confirmado em território maranhense no dia 20 de março de 2020, interiorizando-se a partir deste período. Em meio a isso, busca-se compreender a dinâmica da distribuição espaço-temporal da Covid-19 em território maranhense mediante o uso da Cartografia. Para isso, utiliza-se de dados provenientes dos boletins diários da Secretaria de Estado da Saúde (SES/MA) em conjunto a técnicas estatísticas, bem como uso da Cartografia e do Geoprocessamento junto ao Sistema de Informações Geográficas (SIG) para mapear e analisar o processo da difusão do SARS-CoV-2 no Maranhão. Assim, o uso desses instrumentos se faz essencial para acompanhar a disseminação da Covid-19, compreender o fluxo e deslocamento de pessoas, a distribuição e acesso aos serviços de saúde, além de aspectos ligados a desigualdade no acesso a este tipo de serviço. Seu uso auxilia no processo de tomada de decisão por parte da gestão pública permitindo alocar recursos para minimizar os impactos da pandemia da Covid-19 no território maranhense.
Condiciones para una estética althusseriana en España: paradigma circulatorio e historia intelectual
Authors: Garrido Violeta
Published: February 2023

El presente artículo se propone exponer de manera general las condiciones históricas, políticas y editoriales en las que circularon las obras del filósofo francés Louis Althusser en las postrimerías de la dictadura franquista, prestando especial atención a las lecturas que se hicieron de las mismas desde el campo académico y, fundamentalmente, desde los estudios literarios. Se trata de un asunto insuficientemente abordado hasta el momento y que pasa por alto una de las principales contribuciones a la teoría literaria contemporánea, el estudio de Juan Carlos Rodríguez sobre las primeras literaturas burguesas españolas y europeas. Para ello, utilizaremos algunas de las herramientas brindadas por la sociología de los intelectuales de inspiración bourdieusiana.
Sobrevivir al poeta
Authors: Delgado Sergio
Published: February 2023

Este trabajo, escrito luego de la segunda edición, revisada y aumentada, de la Obra completa de Juan L. Ortiz (2020), es al mismo tiempo una memoria y un balance de las distintas «publicaciones» de la obra del poeta. De la edición mencionada, pero también, de manera retrospectiva, de las precedentes: la edición de la obra reunida, en tres tomos, con el título de En el aura del sauce (1971) y la primera edición, luego de la muerte del Ortiz (1978), de la Obra completa (1996). Este trabajo, en definitiva, es una reflexión sobre la historia de la escritura poética y sus «maquinarias», sobre el verso como instrumento, el poema como dispositivo y el libro como objeto. Una reflexión sobre la vida y la sobrevida del poeta en su obra.
Basic Parameters of Medical Textile Materials for Removal and Retention of Exudate from Wounds
Authors: Riabchykov Mykola , Nazarchuk Liudmyla , Tkachuk Oksana
Published: February 2023

The article focuses on predicting the properties of textile materials intended for the treatment of wounds. The main requirements for medical textile materials for liquid transportation were identified. Exudate from wounds and therapeutic fluids from a dressing must move through material with the necessary efficiency. This ensures that unwanted substances are removed from the wound and the necessary moisture is maintained. These requirements can be provided using a mathematical model of the process. Such a model can be substantiated by solving a non-linear differential diffusion equation. For this purpose, the function of changing the moisture content inside a textile material was approximated using a polynomial function that satisfies the boundary conditions. This approximation made it possible to reduce the problem to the solution of an ordinary differential equation with respect to time. The obtained analytical solution of the change in moisture content with respect to time and coordinate includes two diffusion constants. The results of macro-experiments, together with analytical results, made it possible to determine the diffusion coefficient and the nonlinearity coefficient in an explicit form. The results made it possible to predict the moisture content at a given point of textile material at any given time, the total amount of absorbed liquid and the intensity of absorption. The resulting function can recommend the geometric and physical parameters of medical textile materials for the treatment of wounds with a given intensity of exudate sorption.
Determination of the velocity of seismic waves for the location of seismic station of Zatriq, Kosovo
Authors: Hasi Nazmi , Hasi Latif , Syla Naim
Published: February 2023

Seismological investigations are of a particular importance for the behavior of engineering structures and other structures of interest for the society under earthquake effects. This refers not only to the location of the structures themselves but also to their wider surrounding. In this context, it is important to determine the speed of seismic waves to define the possible location for the construction of secondary seismic stations. Also, determination of the speed of the seismic waves is very important to determine the compactness of the rock, where the seismic equipment is placed to increase the efficiency of monitoring the seismic activity.
Current performance of C-reactive protein determination and derivation of quality specifications for its measurement uncertainty
Authors: Borrillo Francesca , Panteghini Mauro
Published: February 2023

From External Quality Assessment data, current harmonization of CRP measuring systems appears to be satisfactory, the inter-assay CV being well below 10%. The inter-method variability is even better (close to 3%) when the widely used measuring systems are compared at CRP concentrations employed as cut-off for detecting sub-clinical infection (i.e., 10.0 mg/L) and measurement variability estimated, according to ISO 20914:2019 Technical Specification, from the intermediate within-lab reproducibility of 6-month consecutive measurement data. According to the state-of-the-art model (which is better suited for CRP), the maximum allowable measurement uncertainty (MAU) for CRP measurement on clinical samples with 10.0 mg/L concentrations is 3.76% (desirable quality). As measurement uncertainty (MU) of the only available reference material (ERM-DA474/IFCC) is ∼3%, to fulfil desirable MAU on clinical samples, IVD manufacturers should work to keep the contribution of remaining MU sources (commercial calibrator and intermediate within-lab reproducibility) lower than 2.3%.
The Professional Standard of Care in the Republic of Ireland and the United Kingdom
Authors: Harder Sirko
Published: February 2023

This article discusses the rules applied by the courts in the Republic of Ireland and the United Kingdom in determining whether the defendant in a negligence action attained the required standard of care in performing a professional task. It will discuss the effect of the defendant’s adherence to a practice widely accepted in the relevant profession at the time, and the effect of expert witnesses testifying that they regard the defendant’s conduct as proper. This article also discusses the different rules applying to the provision of certain information by a professional.
The Immanent Tensions of ‘Compensation’ of Loss of Life – A Multidimensional Model and Some Global Thoughts Based on the Recent Legislative Reform in Hungary
Authors: Fuglinszky Ádám
Published: February 2023

Immanent tensions of tort law vibrate apparently with greater amplitude regarding the so-called ‘loss of life’ claims of secondary victims (family members) for non-pecuniary damages. The loss of a loved one cannot be expressed in terms of money, yet tort law attempts to do so. Deterrence and punishment are basically alien to civil liability (at least in the civil law tradition), but there is an element of punishment involved. It is impossible to serve two masters; nevertheless, both predictability of law and individual justice are sought at the same time. There is a constant fear of unfounded claims, yet there is also a tendency to release the surviving family member(s) from the burden of proving feelings that are difficult to quantify (if possible at all).

In this paper, a multi-dimensional model is created for a better understanding, based on those tensions and the possible combinations of solutions provided by the legal systems to them. While some contrasts are highlighted (eg first, having legislative acts according to which particular relatives are entitled to compensation and in what particular amount; or on the contrary, leaving matters to the discretion of the trial judge; and second, whether the degree of relation matters and/or emotional proximity is crucial), reference is also made to the still unanswered basic questions, such as what actually is the loss to be compensated: the grief and sorrow felt in itself, the aggravation of the claimant’s own life (among others, loss of guidance, care and companionship), the loss to the integrity of the family as a value, or finding the energy to deal with the loss and therefore not investing in other constructive purposes or life goals?

The analysis of the author’s own legal system, ie of the Hungarian approach, recently rich in variety, and some additional comparative remarks provide the first test of the model and allow some general conclusions.
Stability Analysis of B.1.1.529 SARS-Cov-2 Omicron Variant Mathematical Model: The Impacts Of Quarantine And Vaccination
Authors: Dickson S. , Padmasekaran S. , Chatzarakis G. E.
Published: February 2023

In this study, an epidemic mathematical model for Omicron, denoted as B.1.1.529 SARS-Cov-2 Variant, is constructed. Covid-19 vaccines are considered here to ensure the host population’s safety across the model. The fundamentals of positivity and boundedness in this model have been investigated and validated. The reproduction number was calculated to determine whether or not the disease would spread further in Tamilnadu. Infection-free steady-state solutions that exist are asymptotically stable locally when R
0 < 1 and globally when R
0 > 1. Also Infection-present steady-state solutions that are locally stable are discovered when R
0 < 1. Finally, the current Omicron variant pandemic data from Tamilnadu, India, is validated.
Versión, subversión y parodia: propuestas posfeministas en “Malena, una vida hervida” de Almudena Grandes
Authors: Rueda Acedo Alicia
Published: February 2023

En este artículo se analiza “Malena, una vida hervida” de Almudena Grandes como relato paradigmático de las propuestas posfeministas que la autora española presenta en su obra narrativa, la cual recurrentemente se distancia y critica los modelos patriarcales de mujer tradicional, al mismo tiempo que cuestiona varios presupuestos feministas.
“Malena, una vida hervida”, integrante de la colección Modelos de mujer, critica los parámetros estéticos que establece la sociedad, y replantea el erotismo y su vinculación con la comida. Para ello, Grandes propone una versión, subversión y parodia tanto de modelos masculinos como femeninos a la vez que exhibe la incapacidad de escapar al modelo femenino impuesto por el patriarcado.
Palabras clave: Almudena Grandes, posfeminismo, modelos patriarcales, erotismo, comida.
El corazón y el alma en la poesía de Ramón López Velarde
Authors: Rosas Martínez Alfredo
Published: February 2023

En la poesía de Ramón López Velarde es fundamental la presencia del corazón y del alma. Ambos conceptos no son simples y únicos, sino complejos y diversos. Hay un corazón confesional e íntimo, llamado “Corazón de San Agustín”; un corazón como órgano del cuerpo, conocido como “Corazón de Harvey”; y un corazón simbólico, el cual recibe el nombre de “Corazón de León”. En correspondencia con estos elementos, hay un alma individual, perteneciente al sujeto lírico; un Anima mundi, relativa a la belleza del mundo; y un Alma Superior, la cual remite al mundo de las ideas platónicas o arquetípicas. Con base en un enfoque propio de la Mitocrítica, se demuestra la importancia de la presencia del símbolo, del mito y del arquetipo en la poesía de López Velarde. 
Palabras clave: corazón, alma, mitocrítica, poesía, López Velarde.
El pensamiento de Zambrano, premisas para una filosofía integradora
Authors: León Padilla Miguel Pedro
Published: February 2023

El nuevo siglo ha receptado acríticamente un conjunto de prejuicios antropológicos —bajo la apariencia de rigor científico— que fundamentan una visión fragmentaria y desajustada del hombre. En este contexto, el lúcido pensamiento de María Zambrano ofrece las premisas básicas para reintegrar la comprensión del misterio del hombre. Comenzando por la búsqueda y empleo de un uso de la razón que se adecúe convenientemente a la peculiaridad de lo humano: la razón poética; continuando por la recuperación de saberes olvidados, como la metafísica, aplicada al estudio de la persona, y concluyendo en el énfasis de la omnipresencia de lo divino y la pasión humana por relacionarse con la divinidad, clave de reintegración de su pluridimensionalidad.
Palabras clave: Antropología, flosofía, razón, metafísica, Zambrano.
"La mujer no existe”. Sobre la violencia conceptual y simbólica del post-feminismo constructivista
Authors: Binetti Maria
Published: February 2023

Bajo el supuesto de que la ontología es un mero metarrelato totalitario, colonialista y normativo, la postmodernidad interpretó ‒por defecto‒ que la producción de puras ficciones discursivas e identificaciones sociales sin compromisos ontológicos representaría de suyo una performance liberadora. En el caso concreto de la diferencia sexual, la postmodernidad queer o trans-feminista instaló que la producción socio-imaginaria de múltiples géneros auto-definidos liberaría a las mujeres de ser tales. Las siguientes páginas intentarán explicar por qué la des-ontologización de la diferencia sexual y su sustitución por incontables identificaciones socio-imaginarias es de suyo violencia conceptual, epistémica y simbólica, base de cualquier otra violencia.
Palabras clave: Teorías queer, post/trans-feminismo, diferencia sexual, géneros, interseccionalidad.
Apuntes para una cartografía de los pasos del psicoanálisis por Cuba después de 1959 (I): El fantasma perseguido
Authors: Machin Suarez Raudelio , Santana Romero Liudmila de la C.
Published: February 2023

This work intends to highlight several points for a study of the circulation, reception, imagining, praxis, and institutionalization of psychoanalysis in post-1959 Cuba. Rather than focusing on traditional historiographical logic, it aims to weave together contextual, social, economic, and political elements that could relate to the way in which this system of ideas was perceived, assimilated, and at the same time, relatively marginalized in this Caribbean land. We seek several points of comparison with other Latin American countries and lay the groundwork for an in-depth study. Works on this subject in Latin America are taken as a reference point, specifically in Argentina, Brazil, and Chile. This work distinguishes itself by emphasizing the imaginary relationship, social praxis, and institutionalization, to attempt to understand the difficulties of the insertion of psychoanalysis on the island. This first installment runs until approximately 1980, while the second continues the trajectory from the 1980s to the mid-2000s, a period of relative rebirth in psychoanalysis.
Franco-German tandem: setting up for the future
Authors:   Institute of Europe of the Russian Academy of Sciences, Rubinskiy Yuriy , Sindeev Aleksey ,   Institute of Europe of the Russian Academy of Sciences
Published: February 2023

The visit of Chancellor O. Scholz to China (without the participation of President E. Macron) allowed analysts and the world media to conclude that the Franco-German tandem is in a crisis. The authors set the goal of analysing the tandem problems at present and identifying a future model of cooperation. Contrary to wide-spread views, the authors believe that the deep essence of the crisis lies in difficulty for the tandem participants to correct and manage the asymmetry of relations and processes at national, European and international levels. The article defines the future model of cooperation between France and Germany as selective partnership.
Development and Validation of a Postoperative Prognostic Nomogram to Predict Recurrence in Patients with Persistent Atrial Fibrillation: A Retrospective Cohort Study
Authors: Deng Cong-Ying , Zou Ai-Lin , Sun Ling , Ji Yuan
Published: February 2023

Background: Patients with persistent atrial fibrillation (PsAF) have a high risk of recurrence after catheter radiofrequency ablation. Nevertheless, no effective prognostic tools have been developed to identify these high-risk patients to date. This study sought to develop and validate a simple linear predictive model for predicting postoperative recurrence in patients with PsAF.

Methods: From June 2013 to June 2021, patients with PsAF admitted to our hospital were enrolled in this single-center, retrospective, observational study. The characteristics substantially associated with recurrence in patients with PsAF were screened through univariate and multivariate logistic regression analysis. The receiver operating characteristic curve was used to assess the predictive significance of the nomogram model after nomogram development. Furthermore, to assess the clinical value of the nomogram, we performed calibration curve and decision curve analyses.

Results: A total of 209 patients were included in the study, 42 (20.10%) of whom were monitored up to 1 year for recurrent AF. The duration of AF episodes, left atrial diameter, BMI, CKMB, and alcohol consumption were found to be independent risk factors (P<0.05) and were integrated into the nomogram model development. The area under the curve was 0.895, the sensitivity was 93.3%, and the specificity was 71.4%, thus indicating the model’s excellent predictive ability. The C-index of the predictive nomogram model was 0.906. Calibration curve and decision curve analyses further revealed that the model had robust prediction and strong discrimination ability.

Conclusion: This simple, practical, and innovative nomogram can help clinicians in evaluation of the risk of PsAF recurrence after catheter ablation, thus facilitating preoperative evaluation, postoperative monitoring and ultimately the construction of more personalized therapeutic protocols.
Machine Learning for Predicting the Development of Postoperative Acute Kidney Injury After Coronary Artery Bypass Grafting Without Extracorporeal Circulation
Authors: Zheng Sai , Li Yugui , Luo Cheng , Chen Fang , Ling Guoxing , Zheng Baoshi
Published: February 2023

Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication that increases morbidity and mortality after cardiac surgery. Most established predictive models are limited to the analysis of nonlinear relationships and do not adequately consider intraoperative variables and early postoperative variables. Nonextracorporeal circulation coronary artery bypass grafting (off-pump CABG) remains the procedure of choice for most coronary surgeries, and refined CSA-AKI predictive models for off-pump CABG are notably lacking. Therefore, this study used an artificial intelligence-based machine learning approach to predict CSA-AKI from comprehensive perioperative data.

Methods: In total, 293 variables were analysed in the clinical data of patients undergoing off-pump CABG in the Department of Cardiac Surgery at the First Affiliated Hospital of Guangxi Medical University between 2012 and 2021. According to the KDIGO criteria, postoperative AKI was defined by an elevation of at least 50% within 7 days, or 0.3 mg/dL within 48 hours, with respect to the reference serum creatinine level. Five machine learning algorithms—a simple decision tree, random forest, support vector machine, extreme gradient boosting and gradient boosting decision tree (GBDT)—were used to construct the CSA-AKI predictive model. The performance of these models was evaluated with the area under the receiver operating characteristic curve (AUC). Shapley additive explanation (SHAP) values were used to explain the predictive model.

Results: The three most influential features in the importance matrix plot were 1-day postoperative serum potassium concentration, 1-day postoperative serum magnesium ion concentration, and 1-day postoperative serum creatine phosphokinase concentration.

Conclusion: GBDT exhibited the largest AUC (0.87) and can be used to predict the risk of AKI development after surgery, thus enabling clinicians to optimise treatment strategies and minimise postoperative complications.
Preparation of Equine Immunoglobulin F(ab′)2 against Smallpox and Evaluation of its Immunoprotective Effect
Authors: Shi Bochang , Han Hui , Tan Lingyun , Liu Yuan , Yan Fang , Li Bo , Zheng Naxin , Li Min , Zhao Liyan , Li Huabin , Fan Tietong , Zhang Zhiping , Li Xinyu , Tian Chongyu , Zheng Yuanqiang , He Wei , Zhao Zhongpeng
Published: February 2023

Objective:

Smallpox, a severe infectious disease caused by the smallpox virus, causes a death rate as high as 30% within 15-20 days after infection. Therefore, development of anti-Smallpox product as a strategic reserve is urgently needed.

Methods:

We prepared and tested pepsin-digested F(ab′)2 fragments of serum IgG from horses.

Results:

Transmission electron microscopy indicated that the purified virus showed morphology consistent with VVTT. The titer was above 1.0 × 107 PFU/mL. The purity of the antigen exceeded 90%, according to HPLC. After purification and cleavage, the yield of the purified product F(ab′)2 was approximately 1.3%, its purity exceeded 90%, and the neutralizing antibody titer exceeded 1:3200. F(ab′)2 fragments had good preventive and therapeutic effects in mice at antibody doses of 5.2 mg/mL and 2.6 mg/mL. The viral loads of the drug-treated mice were suppressed to varying degrees, and the higher dose groups (5.2 and 2.6 mg/mL) showed a 2-3 fold lower viral load than that in the control group.

Conclusion:

A process for producing equine immunoglobulin F(ab′)2 against VVTT was established. The prepared horse anti-smallpox immunoglobulin product had good neutralizing antibody effects on VVTT. The highly purified preparation may serve as a potential candidate for smallpox treatment.
“Blushing before the Muses”
Authors: Wilds Travis
Published: February 2023

In recent years, literary critics grappling with the misfit writer Louis-Sébastien Mercier’s sprawling oeuvre have recovered a “modernist” who deploys formal tropes like the fragment or sketch to capture the city’s fugitive qualities. In this essay, I show that Louis-Sébastien Mercier’s little-read Mon bonnet de nuit (My night bonnet) transposes formal indeterminacy to the writing of the everyday, the thinking of thought, and the representation of cosmic space. Mercier’s growing commitment to geocentrism counterbalances Friedrich Schlegel’s call for a “Copernican” poetics, while his writerly hyperproductivity gives rise to a style of indifference and zaniness that offers insight into the creation of “literary value” at the critical juncture when patrons gave way to publishers as mediators of production in European literary history.