bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular mechanisms of the nephroprotective action of polyphenols in experimental chronic kidney disease. Association with hydrogen sulfide system
Authors: Konjuch S.A. , Voloshchuk N.I. , Melnyk A.V. , Denysiuk O.M. , Zhorniak P.V.
Published: May 2020

Annotation. The results of a study of the effects of genistein, resveratrol and quercetin on the main markers of oxidative stress, thiol disulfide equilibrium and the state of the nitric oxide system in rat kidneys after modelling chronic kidney disease (CKD) (5/6 of a single kidney nephrectomy) is shown. Blood and single rat kidney homogenate were used for biochemical studies. Statistical processing of the obtained results was performed in the program “STATISTICA 6.1”. The results are presented as M±m. The significance of the difference between the scores was evaluated using the Student's t-test or the Mann-Whitney U-test. A nonparametric Spearman correlation coefficient was used to determine the correlation between two independent indicators. It was shown that the studied substances, especially quercetin, caused antioxidant activity in CKD, which was manifested by a significant decrease of MDA, CGP and NADPH oxidase activity (by 21.0–40.4%), as well as an increase in SOD activity (by 29.7–38.7%) in kidney compared with untreated animals. Reliable strong correlation (r=ǀ0.65–0.74ǀ) between the H2S content and oxidative stress markers was established. The use of polyphenols in CKD reduced the thiol-disulfide imbalance in rat kidneys: the activity of thioredoxin reductase significantly increased, the content of reduced thiol groups of proteins (by 16.0–66.4%) and the level of disulfides decreased (by 21.1–25.3%), in comparison with untreated animals. Stabilization of the thiol disulfide equilibrium is one of the mechanisms of the effect of polyphenols on the H2S system in the kidneys, since significant and strong correlation relationships were recorded between these indicators and the H2S content (r=ǀ0.63–0.75ǀ). The administration of resveratrol, and especially genistein, was accompanied by an increase in the activity of the eNOS (by 36.3–44.7%) and a decrease in the activity of iNOS (by 15.4–20.9%), in comparison with untreated animals. The NO system in the kidneys is an important molecular target for influence of genistein and resveratrol on the production of H2S during CKD is realized, since reliable strong correlation were recorded between the H2S content and the activity of NO synthase isoforms (r=ǀ0.70–0.75ǀ).
The variation pulsometry correct indicators` modeling in volleyball players with mesomorphic somatotype depending on the anthropometric features of the organism
Authors: Sarafyniuk L.A. , Syvak A. V. , Piliponova V.V. , Dus S.V. , Lezhnova O.V.
Published: May 2020

Annotation. Appropriate cardiointervalographic parameters establishment, for highly skilled athletes of a particular sport, is relevant and can be used for diagnostic purposes and because of connection with the widespread prevalence of cardiovascular pathology. The purpose of the work was to construct regression models of the variations of the pulsometry in volleyball players of the mesomorphic somatotype, depending on the features of anthropometric indicators. The study involved 24 volleyball players with a high level of sportsmanship (from the first adult category to candidates for the master of sports), aged 17–21 years. We carried out anthropometric research by Bunak's method (1941), somatotypological - by the calculated modification of the Heath-Carter method (1990), determination of the component composition of the body weight by the method of Matejko (1992) and cardiointervalographic examination using a computer diagnostic complex “OPTW” following the recommendations of the European and North American Cardiac Association [1996]. The following indicators of variation heart rate were determined: moda, moda amplitude, average minimum and maximum R-R intervals, and variation range. The mathematical models were constructed in the “STATISTICA 5.5” package for Windows using direct stepwise regression analysis. The article presents the results of regression analysis for determining the dependence of variation heart rate indicators in volleyball players of mesomorphic somatotype on the total complex of constitutional characteristics. Mathematical models for determination of individual proper cardiointervalographic parameters based on features of the external structure of the body of youth volleyball players of high level of sportsmanship. The analysis of constitutional predictors that determine the variability of indicators of variation heart rate in a group of volleyball players of mesomorphic somatotype has been performed.
Comparative analysis of the results of 3-hour esophageal-gastric-pH monitoring in patients with combined course of gastroesophageal reflux disease and arterial hypertension depending on the available antihypertensive pharmacotherapy
Authors: Paliy I.G. , Ksenchyn O.O. , Zaika S.V.
Published: May 2020

Annotation. Hypotensive drugs, which patients with arterial hypertension take, can have a negative impact on the motility of the esophagus and lower esophageal sphincter, increasing the likelihood of gastroesophageal reflux disease, and worsen it. The aim is to study the features of acid gastroesophageal refluxes and gastric secretory function in patients with combined course of gastroesophageal reflux disease and arterial hypertension, depending on the available anti-hypertensive pharmacotherapy. Patients were divided into four groups, depending on available monotherapy with valsartan, lisinopril, bisoprolol, and amlodipine. Patients were subjected to 3-hour esophageal-gastric-pH monitoring. We conducted a comparative analysis of the following indicators: the number of acid refluxes, the presence of refluxes lasting more than 5 minutes, the average and maximum duration of episodes of reflux. The values of the minimum pH, maximum pH, average pH and median pH in the esophagus, cardiac part of stomach and stomach body were also compared. The results showed that in the group of patients taking valsartan, there was a significant increase in the number of episodes of acid reflux, an increase in the minimum pH in the esophagus, and an increase in % of time with a pH <4 in the esophagus, unlike patients taking lisinopril or amlodipine. There were no differences in gastro-pH monitoring between patients treated with valsartan, lisinopril, bisoprolol, and amlodipine monotherapy. It indicates that increase of gastroesophageal reflux in the valsartan group was not caused by the acid-induced effect of valsartan, but other factors that lead to a decrease and/or disorganization of esophageal motility.
Analysis of the structure and manifestations of alexithymia in women with depressive disorders with different severity of psychosocial maladaptation
Authors: Isakov R.
Published: May 2020

Annotation. To study the structure and manifestations of alexithymia in women with depressive disorders of various genesis and severity of psychosocial maladaptation, 252 women suffering from depressive disorders, 94 of whom had psychogenic depression (F43.21), 83 women with affective disorders of endogenous nature (F32.0, F32.1, F32.2, F32,3; F33.0, F33.1, F33.2, F33.3; F31.3, F31.4, F31.5), and 75 people have organic depression (F06.3) was surveyed. The study was conducted using clinical-psychopathological and psychodiagnostic methods. It is established that patients with signs of maladaptation had a higher level of alexithymia, both in its individual components and overall severity, compared not only with patients without signs of maladaptation, but also with normative indicators of patients with psychosomatic pathology or neurotic disorders, by the authors of the method testing. However, alexithymic manifestations are highest in patients with organic depression, slightly smaller in patients with endogenous depression, and the lowest in patients with psychogenic depression. The identified patterns should be taken into account when developing treatment and rehabilitation and prevention measures for patients with depression.
The significance of diagnostic aspects of Holter ECG monitoring in verifying the causes of syncopal states in young patients (clinical cases)
Authors: Chirka N.M. , Vakolyuk L.M.
Published: May 2020

Annotation. Fainting (syncope) in a given period of life occurs in almost a third of the population, but only in a small number of cases it is a manifestation of a serious disease. The purpose of this observation is to determine the causes of unconscious conditions in young people without a painful history and the absence of any other clinical manifestations and pathological changes in generally accepted laboratory and instrumental examinations. Holter daily ECG monitoring is today considered one of the most important and most effective ways to diagnose heart rhythm disturbances. This article discusses two cases of syncope in young people. The first clinical case occurred in a guy 24 years old. On an outpatient basis, a survey was conducted. All indicators were within the standard values. The patient was diagnosed with Syncopal conditions of unknown origin. When examining the results of ECG monitoring, the cause of syncope was discovered and established. She turned out to be an intermittent form of AV blockade of the II degree of the II type of highly frequent. The patient was recommended to establish an ECS de mand. The second clinical case occurred in a young patient 40 years old. In this patient, with the help of monitoring, a paroxysmal form of ventricular fibrillation was diagnosed. In these two cases, which we examined in this article, only Holter ECG monitoring is of little diagnostic value for verification of syncope in young patients.
Possibilities of using hemostasis markers and parameters of hemostatic potential for predicting thrombotic complications in patients with CKD stage VD
Authors: Storozhuk O.B. , Shevchuk S.V. , Seleznyova I.B. , Storozhuk L.O. , Dovgalyuk T.V. , Storozhuk B.G.
Published: May 2020

Annotation. Violations in the hemostatic system of patients with chronic kidney disease (CKD) of the VD stage treated with program hemodialysis are associated with a high thrombotic risk. Comprehensive studies of the possible causes and predictors of thrombophilia can improve the therapeutic and prophylactic measures to combat thrombotic complications. The search for available methods for predicting these complications is very relevant. The goal is to develop a method for predicting the development of thrombotic complications in this category of patients, which would allow identifying the degree of hemostasis disorders. We examined 88 patients with CKD VD, treated with program hemodialysis, who determined the fibrinolytic potential and the level of soluble fibrin and D-dimer by enzyme immunoassay. It is proposed to use the developed fibrinolytic coefficient (Fc) to predict thrombotic complications. It was found that the proposed method for assessing hemostasis using Fc makes it possible to objectively characterize the state of the coagulation link and can serve as an indicator of thrombotic risk.
Cost-benefit analysis of accommodation spasm prevention programs for schoolchildren
Authors: Starinets M.O. , Oсheredko O.M.
Published: May 2020

Annotation. The relevance of the study is due to the prevalence of accommodation spasm in schoolchildren and the uncertainty regarding the clinical and economic effectiveness of prevention programs. The aim of the study was to develop a new approach to cost-benefit analysis to evaluate the effectiveness of programs for the prevention of spasm accommodation in schoolchildren. The proposed methodology is based on the economic theory of moral hazard and included analytical optimization with the derivation of the equilibrium model. The data are organized into a dynamic sample of schoolchildren with a panel design with replenishment with first-graders during 2012–2015, followed by observation until 2017 with sample size of 1115. It has been established that from a cost-benefit perspective, additional measures of an expanded prevention program, aimed primarily at improving compliance and improving the management of a standard program, provide a net profit in 42.45% of students (430 out of 1013). It has been established that the benefits of an expanded program increase in terms of cost-benefit compared to the existing one: in the schoolchildren with tonsillitis, burdened heredity, daily continuous computer work for more than 2 hours, the presence of stressful situations, a history of eclipses in the eyes. To evaluate preventive programs, future gains should be considered, since this problem is even more clearly related to the prevention of myopia. This will lead to greater efficiency of the expanded program due to better clinical efficacy (not shown in the article).
Adherence to COPD treatment increase: is it possible to reduce the cost of treatment?
Authors: Sidorov A.A.
Published: May 2020

Annotation. Chronic obstructive pulmonary disease (COPD) makes a significant economic burden for the patients, their families and for the healthcare systems of different countries in general. At the same time the level of adherence to basis therapy is 30–40%. Aim of the study is to determine cost effectiveness of the measures for adherence to COPD treatment increase. 156 patients with COPD (III–IV GOLD) were included into study. The duration of the study was 13 months and it consisted of 6 visits. During each visit the adherence to treatment was measured according to value of inhaler dose counter. The instruction regarding necessity to adhere to basis therapy regimen as well as training of correct inhaler use technique were conducted. The costs for the patient with COPD treatment were calculated for 1 year before the start of the patients’ participation in the study (first year) and during their participation in the study (second year). The average value and standard error of average value were calculated for all the parameters. The comparison of parameters of intergroup differences was made with use of T-test for dependent samples and criterion χ2. It is shown that the adherence to COPD treatment rose from 44.41±1.07% to 75.21±0.78%, i.e. by 30.8% (p<0.001). On the background of adherence increase total cost for the patients treatment due to COPD diminished from 20304.88 ± 976.68 UAH to 9258.13 ± 507.90 UAH, i.e. by 54.4% during the year. Thus, adherence to COPD treatment increase permits to diminish the annual treatment cost for this disease significantly (by 54.4%). Detection of patients' visits frequency to medical institution in order to maintain the level of adherence to treatment which was already achieved has the prospect of further research.
Constitutional and psychological features of the occurrence and course of eczema in men and women (analysis of scientific literature)
Authors: Al-Omary Ala’a Osama Ahmad
Published: May 2020

Annotation. The purpose of the work is to analyze the scientific literature on the constitutional and psychological features of the occurrence and course of eczema. A review of literature indicates that, despite the large number of works on this problem, only a few cases of study of this dermatosis in the key of its association with the constitution and psychotype of the patient are described. Early recognition of this association allows timely detection of dermatosis at an early and even preclinical stage and, through adequate therapy, to achieve a regression of skin manifestations of eczema. The use of genetic markers, in turn, reveals a risk group that includes patients with “eczema constitution “and patients who are torpedoed to conventional therapies. The practical aspect of the problem has become more relevant nowadays given the significant incidence of Ukrainian women and men.
The problem of combined diseases in the reproductive system of the women
Authors: Kruk O.Yu.
Published: May 2020

Annotation. This article highlights the urgent problem of combined diseases of women's reproductive system. On the basis of theoretical analysis, generalized statistics for recent years are presented. The modern concepts of pathogenesis of diseases of the uterus and mammary glands, their correlation, as well as models of diagnosis and treatment are considered. Indeed, a more in-depth understanding of the problems of the combined pathology of the woman’s reproductive system (diseases of the uterus, ovaries, mammary gland), namely etiopathogenesis, diagnostic and treatment algorithms, will reduce the incidence of women of reproductive and perimenopausal age, as well as improve their quality of life. Only having the fullness of information about the state of the reproductive system of women, the doctor is able to prescribe thoughtful and effective treatment.
The issues of alcohol withdrawal syndrome: current state of the problem
Authors: Havrylov O.
Published: May 2020

Annotation. Alcohol addiction is one of the three main health problems in the world, which directly or indirectly increases the mortality rate, wherein it poses the greatest threat to the developed countries of Europe and America. Identification of promising directions for resolving the issue of alcohol withdrawal syndrome with delirium is one of the levers to reduce the consequences of its harmful use. It was made an analysis of the electronic database of scientific publications Pubmed and the latest WHO data, the main approaches to the pathogenesis and intensive care of alcoholic delirium in Ukraine and abroad were highlighted and displayed, clinical and laboratory diagnostic aspects were distinguished. There is a certain vision of the pathogenesis of alcohol withdrawal syndrome as an imbalance in the GABA and glutamate-ergic systems in brain neurons. Diagnostic criteria have been developed and introduced into clinical practice to determine the severity of withdrawal status, as well as sedation-agitation scales, it is not completely determined the influence of electrolyte disturbances, namely magnesium deficiency on the severity of the condition, the effectiveness of sedation and mortality. The optimal way to increase the effectiveness of the treatment of alcoholic delirium, which would ensure an adequate level of sedation, has not yet been found all over the world, at the same time, without increasing the risk of complications in the form of an overdose of tranquilizers and hypnotics, both in case of their isolated and combined use. The possibility of using chelate compounds containing GABA in themselves, as well as organic magnesium salts, namely gluconic acid salts, is promising.
ТЕХНОЛОГІЯ ВИГОТОВЛЕННЯ ПОЛЕГШЕНИХ СКЛАДІВ ЦЕМЕНТНИХ СУХИХ БУДІВЕЛЬНИХ СУМІШЕЙ З МІНЕРАЛЬНИМИ ДОБАВКАМИ
Authors: Бондар А. В.
Published: May 2020

The article deals with the technological features of manufacturing of lightweight cements of dry building mixtures with mineral additives. The technology of obtaining mortars from dry mixtures should take into account the fact that the processes of hydration of cement binder occur with insufficient water. Therefore, the possibility of obtaining lightweight dry mixtures based on Portland cement and mineral additives with the use of foaming additives is investigated. The use of a complex of technological operations allows you to obtain mixtures for the installation of warm floors, which are characterized by stable technological and physical and mechanical properties, as well as the simplicity and economy of manufacturing technology. Effective mixtures of porous structure have been obtained from for the warm floors on the basis of conventional dense (heavy) fillers and fillers, such as quartz sand, clay, carbonate sand, ash-removal of thermal power plants. The technological scheme of factory production of dry mixtures has been obtained while saving the binder component.
PRINCIPLES OF WORKING WITH SOUND IN M. SHALYGIN'S ESSAY “RED BELLS OF JUAN MIRO”
Authors: Dzhabrailova-Kushnir E. D.
Published: May 2020

The aim of the research is to establish the specifics of M. Shalygin's work with sound (using the work “Red Bells of Juan Miro" as an example), which will allow a better understanding of the originality of his music, as well as the composer's method of organizing sound and its (sound) interpretation. Thus, using the integrated method which combines the auditory and structural methods of analysis, as well as the analysis of the spectrogram of the work, the properties of the timbre elements, the principles of the organization of musical tissue, as well as the features of composer thinking and creative methods will be established od M. Shalygin.
CORRUPTION NETWORKS: HOW IT REMAINS DOING AND PERSISTS
Authors: Yuri Verlanov  , Alexander Verlanov
Published: May 2020

Using the well-known three-tier model of corruption, we analyze the construction of an elementary corruption network. Considering the public choice theory and the organization culture theory as our theoretical basis, we propose principles of the corruption network functionality, including horizontal links which provide participants with the necessary protection from the risks of been exposed. Elementary corruption networks use organizational mechanisms which, despite the rigid rules of functioning, make them sufficiently flexible and secure. At the same time, even though the main “productive force” of the system is the vertical “client-agent” relationship, the networks, through horizontal links, can unite, spreading out towards many influential spheres of society, where they support each other and thus stay viable. In such an environment the fight against corruption seem to be a simple demonstration of the network’s strength, which gets rid of the participants who violate “rules of the game”.
СТРУКТУРА КОМУНІКАТИВНОЇ КОМПЕТЕНТНОСТІ МАЙБУТНІХ УЧИТЕЛІВ МИСТЕЦЬКИХ ДИСЦИПЛІН: СУЧАСНИЙ ФОРМАТ
Authors: Лупак Н. М.
Published: May 2020

The article deals with the essence of communicative competence of future teachers of artistic disciplines in the context of modernizing education and expanding the boundaries of art communication. The theoretical analysis of scientific sources on the problem of formation of communicative competence of future teachers, in particular, teachers of artistic disciplines has been carried out. The own definition of the notion «communicative competence» taking into account modern requirements for the professional training teacher of art has been proposed. The main tendencies for the structure of components of communicative competence as a system have been revealed. The own vision of the structure of communicative competence of future teachers of artistic disciplines, which is presented as a model, has been substantiated. The main structural elements have been demonstrated: criteria (axiological, cognitive, personal-active), components (valuable-motivational, informational-semantic, algorithmical-active, artistic-creative), indicators of formation of communicative competence.
ВИДЫ ЭНЕРГОРЕСУРСОВ И ВОЗМОЖНОСТИ РАЗВИТИЯ АЛЬТЕРНАТИВНОЙ ЭНЕРГЕТИКИ НА ОСНОВЕ ВОЗОБНОВЛЯЕМЫХ ИСТОЧНИКОВ ЭНЕРГИИ В УЗБЕКИСТАНЕ
Authors: Мaxмaдиeв Б. C.  , Oчилoв М. A.  , Мирзаев Ш. Н.  , Юлдашов С. Ш.
Published: May 2020

Uzbekistan has sufficient potential for the development of alternative sources. The development of renewable energy is a prerequisite for the conservation of energy sources. The article analyzes the degree of use of traditional energy resources, the needs of the power industry, the potential of renewable energy sources, the possibilities of using and cooperation with foreign countries on the development and use of Uzbekistan.
ДОСЛІДЖЕННЯ ГОСТРОЇ ТОКСИЧНОСТІ ПОХІДНИХ 1,2,4-ТРІАЗОЛУ, ЩО МІСТЯТЬ В СВОЄМУ СКЛАДІ ЯДРО 1Н-ТЕТРАЗОЛУ
Authors: Фролова Ю. С.  , Каплаушенко А. Г.
Published: May 2020

The design of new drugs is a rather complex and multi-stage process. The modeling and creation of new biologically active compounds are one of the stages of this operation. One of the important stages of preclinical trials is the study of acute toxicity of newly synthesized compounds. Great interest in this branch is nitrogen-containing heterocycles, namely 1,2,4-triazole and their derivatives.Therefore, the purpose of our work is to study acute toxicity among new derivatives of 5-(1H-tetrazole-1-yl)-4-R-3-thio(amino)-1,2,4-triazole. The study of acute toxicity was carried out by the method of V. B. Prozorovsky on the white nonlinear rats.As a result of the experiments, acute toxicity of the 41 synthesized compounds was determined. The value of the LD50 of new derivatives of 5-(1H-tetrazole-1-yl)-4-R-3-thio(amino)-1,2,4-triazole is in the range of 357-1060 mg/kg, and according to the classification of Sidorov I. K. belong to IV and V toxicity classes.
CHARACTERISTICS OF THE CONTENT OF PEDAGOGICAL CONDITIONS FOR EDUCATION OF PHYSICAL QUALITIES OF EDUCATIONAL SUBJECTS "SCHOOL-SECTION" IN THE PROCESS OF EXTRACURRICULAR WORK FROM PHYSICAL EDUCATION
Authors: Tetyana Рolulyashchenko  , Yuri Рolulyashchenko
Published: May 2020

Content of pedagogical conditions of education of physical qualities of subjects of the educational space, "School-Section" in the process of extra- curricular work on physical education. The article deals with topical issues related to the creation of certain pedagogical conditions that promote the upbringing of physical qualities of pupils of the school. The concept of the "condition" in the scientific sources is revealed. The importance of creating certain pedagogical conditions is proved, as a qualitative organization of the educational process on physical education of the children of the school depends on them. The pedagogical conditions that allow to consider extracurricular activity of students of the basic school as the activity having significant educational potential for solving modern problems of physical education in institutions of general secondary education, as well as for development of physical qualities of students, namely: creation of a single educational space "School - Section ", aimed at uniting the educational potential of the subjects of the educational environment for the organization of extracurricular classes on cycling sports and the education of the physical qualities of the pupils of the school; raising the level of pedagogical skill of the trainer-teacher; scientific and methodical provision of the process of raising the physical qualities of cyclists; organization of psychological and pedagogical support for students of the main school in the process of extracurricular activities in cycling.
РОЗШИРЕННЯ СФЕРИ ЗАСТОСУВАННЯ КРИМІНАЛЬНОГО ЖАРГОНУ
Authors: Левченко Т. М.
Published: May 2020

The article analyses the functioning and stylistic peculiarities of criminal slang in the language of mass media at structural and semantic level; ways of inclusion of slang into the system of modern Ukrainian language are traced; expressive and emotional potential of slang in modern journalistic discourse is analyzed; semantic modifications and functional specificity of slang and its influence on modern Ukrainian language were found out; it was mentioned, that figurative senses of verbs in criminal slang are socially conscious, since they are distinguished in phrases, sentences, contextual, but most of them are not fixed in dictionaries; it was determined, that despite its initial isolation and mystery, criminal slang significantly fills up modern spoken language; criminalization of different kinds of discourse, that significantly promote to the forming of “general slang”, occurs.
СУЧАСНІ МОДЕЛІ ТА ФОРМИ ВИКОРИСТАННЯ ІНФОРМАЦІЙНО-КОМП’ЮТЕРНИХ ТЕХНОЛОГІЙ В ОСВІТІ
Authors: Дзвінчук Д. І.  , Радченко О. В.  , Качмар О. В.
Published: May 2020

The paper systematizes and describes the leading world approaches to the use of information and computer technologies in educational institutions in the process of modernization of current educational systems in accordance with the latest requirements of the information society. It is noted that the information society gives the humanity a fundamentally new tool of life that is characterized by the possibility of operating large volumes of information without territorial and time boundaries and displays information-knowledge at the level of the leading producer of public goods. All this leads to a review of the key functions of modern education, when the possession of information and computer technology becomes the main competence requirement for the pupil, student, and every person at each stage of his/her life.The authors substantiate the necessity of creating a system of "total computer literacy" and total informatization of the national education system, wide introduction in modern educational institutions of modern models and forms of use of information and computer technologies, introduction of the national education system to the global educational space at the institutional, environmental and personal levels. It is concluded that today our state faces a difficult task of ensuring the conformity of the basic approaches, principles and instruments of the educational process to the requirements of the transition to the era of the information society in regard to the modernization of the system of national education. We have to invest in the development of domestic innovative ICT products ahead of schedule. Technology and informatization of the educational process must become priority tasks of education reforms from pre-school education institutions to higher education and research institutions, in order not to stay away from the advancement towards the global information society.
РОЗПОВСЮДЖЕНІСТЬ ТА ПРИЧИНИ ПІДВИЩЕННЯ АРТЕРІАЛЬНОГО ТИСКУ СЕРЕД СТУДЕНТІВ 3 КУРСУ ОДЕСЬКОГО НАЦІОНАЛЬНОГО МЕДИЧНОГО УНІВЕРСИТЕТУ
Authors: Швабовська Т. М.  , Коломієць С. М.  , Чернишова К. С.
Published: May 2020

The work is aimed at detecting episodes of increased blood pressure among third-year students of ONMed. Questionnaires, blood pressure measurements, and 525 students' stress tests were conducted. A significant percentage (32.87%) of those who had episodes of increased pressure during the year was detected. Among them a certain number of small diseases of the thyroid gland, kidneys and obesity of the 1st and 2nd st, but most do not indicate any diseases. About half have a burdened family history of arterial hypertension. Students who had episodes of arterial hypertension elevation had a moderate to high stress level indicating psycho-emotional strain.
КРОС-МЕДІЙНІ ІНСТРУМЕНТИ МОНЕТИЗАЦІЇ ТЕЛЕВІЗІЙНОГО Й ІНТЕРНЕТ-КОНТЕНТУ
Authors: Черемних І. В.
Published: May 2020

The article is devoted to the problems of finding new forms of interaction between various media market players and new tools for converting TV and Internet content into profit. Changing the paradigm of consumption of TV and online content creates new conditions for the functioning of media business in Ukraine. Media can effectively monetize content through cross-platform processes such as co-branding, sampling, media baying, PayWall, b2b, b2c partnership, Transmedia Storytteling and others. First of all, it concerns the co-operation of traditional and Internet TV, PAY-TV, IPTV / OTT, digital, cable and satellite penetration, TV and Internet content producers, operators, providers. Through the cross-media consolidation of resources, the combination and distribution of content, players of the media market have the opportunity to successfully finance their budgets and receive greater dividends from the integration of efforts.
THE TEACHER’S ACTIVITY PECULIARITIES IN THE FUTURE TEACHERS’ SYSTEM PREPARATION FOR THE SPIRITUAL AND MORAL DEVELOPMENT OF ELEMENTARY SCHOOL PUPILS IN THE CROSS- CULTURAL SPACE
Authors: Shevchenko Yuliia
Published: May 2020

The article deals with the peculiarities of the teacher’s professional activity in the system of training future teachers for the spiritual and moral development of primary pupils in the cross-cultural space. There are shows the role and influence the contest of education during process of professional training.
MULTIPROCESSOR MODELING TECHNOLOGIES FOR THE APPLIED STATISTICAL TASKS
Authors: Shvachych G. G.  , Sazonova M. S.  , Zaporozhchenko O. E.  , Karpova T. P.  , Sushko L. F.
Published: May 2020

The work considers the multiprocessors technologies of modeling for Monte Carlo tasks. It is shown that only application of the modern super productive systems permitted the new way to realize the mechanism of corresponding partitioned computations. The calculating schemes that supply to provide the increase of productivity and calculations' speed effectiveness are shown. In this article the modified algorithm of parallel calculations is offered based on the Monte Carlo method. Here every calculator has its own random generator of numbers. Thus intermediate calculations come true independently on the different, separately taken blades of cluster, "calculators". The results are already processed on some separately taken master -blades ("analyzer"). This allows to get rid from the necessary presence of router-communicator between the random generator of numbers and "calculator". Obviously, that such decision allows to accelerate the process of calculations. It is shown that the parallel algorithms of the Monte Carlo method are stable to any input data and have the maximal parallel form and, thus, minimal possible time of realization using the parallel computing devices. If it is possible to appoint one processor to one knot of calculation. Thus the realization of calculations becomes possible in all knots of net area in parallel and simultaneously.
ОЦЕНКА «КАЧЕСТВА ОБРАЗОВАНИЯ» В ВЫСШИХ УЧЕБНЫХ ЗАВЕДЕНИЯХ (НА ПРИМЕРЕ БАТУМСКОЙ ГОСУДАРСТВЕННОЙ МОРСКОЙ АКАДЕМИИ)
Authors: Диасамидзе Мзия  , Такидзе Ирма
Published: May 2020

The article addresses the problem of higher education - improving the quality of graduates' professional training, provides a brief analysis of research results, Recommendations on how to use the results “Quality of education” is a complex characteristic of education, the task of which is to train specialists who are competitive in the world market. It is impossible to develop a single, scientifically based system of indicators for the quality of student training, since the education system is different in all countries of the World, moreover, a different system of training students, which is one of the influencing factors on the quality of Higher Education. It is necessary to take into account the specifics of the university.One of the elements of the quality assessment system is monitoring, which is considered to be a comprehensive system for diagnosing the quantitative and qualitative characteristics of the effectiveness of an educational system. The assessment of the quality of education should be formed as a cumulative indicator of all the qualities that influence the educational process. During the work we used the results of sociological research of the subjects of the educational process: students, teachers, monitoring of the educational process (academic performance of students).
РОЛЬ ДИЗАЙНА В ФОРМИРОВАНИИ АРХИТЕКТУРНОЙ СРЕДЫ В ИСТОРИЧЕСКИХ ГОРОДАХ УЗБЕКИСТАНА
Authors: Мирпулатова Мунис Акмаль
Published: May 2020

This article discusses the problem of the relationship between the “old” and “new” in the architectural environment of the historical cities of Uzbekistan. Great importance is attached to the role of the designer in creating a harmonious urban environment and meeting the sociocultural needs of the population.
ПРОБЛЕМА СОЦИАЛЬНОГО НЕРАВЕНСТВА В КОНТЕКСТЕ ФОРМИРОВАНИЯ В РОССИИ "ОБЩЕСТВА РАВНЫХ ВОЗМОЖНОСТЕЙ"
Authors: Ю. В. Колин
Published: May 2020

Global trends show the importance of social inequality for the prospects for social growth. The danger to Russian society of the process of social polarization has been revealed.The lack of attention on the part of the authorities to the problem of social inequality and the formation of an "equal opportunity society" in Russia has been determined. The importance of developing human capital to address catch-up development and the formation of an "equal opportunity" society has been substantiated
PROFESSIONAL DEVELOPMENT OF THE STATE OFFICE OF UKRAINE HUMAN RESOURCES
Authors: Kachan (Melnyk) Ya. V.
Published: May 2020

The article deals with the clarification of the essence of professional development of public servants of the State Employment Service of Ukraine. The article proves that the requirements, which society nowadays places in the professional activity of public servants, envisage not only increased responsibility and effectiveness in its implementation, but also continuous improvement of the level of its professional qualification by civil servants. For public servants to qualify for their duties today it is not enough to possess only narrow-profile knowledge, they need the knowledge and understanding of the mechanisms of interaction of the state, society and individual citizens. It is established that for today professional development of public service is fundamental in the context of postgraduate education of civil servants, because any political strategies are formed and implemented through the human prism. The review of professional development is outlined as: systematically organized process of continuous professional training of the personnel for its preparation for implementation of new production functions, professional qualification promotion, formation of reserve managers and improvement of personnel structure; providing and organizing the learning process to achieve the goals set by the organization; improving skills and competences, expanding knowledge, raising competency, inclining and learning enthusiasm at all levels of the organization, contributing to continuous growth.
Psychological and pedagogical conditions for the support of gifted children on the experience of a private lyceum named after G.V. and N.G. Riumin of Ryazan
Authors: Shiltsova Julia Vyacheslavovna , Arkharova Lyudmila Ivanovna , Korchagina Larisa Mihajlovna
Published: May 2020

The experience of psychological and pedagogical support of gifted children, which consists mainly in the creation of certain conditions in a private educational institution is presented in the article. On the basis of a private lyceum named after G.V. and N.G. Riumin of Ryazan, created by the founder N.V. Riumin – candidate of psychological sciences and by its director L.I. Arkharova – candidate of pedagogical sciences, head of the Pedagogy and Teacher Education Department at FSBEI of HE " Ryazan State University named for S. Yesenin", the experience of cooperation of higher education and general education institutions in the formation and upbringing of gifted children has been studied. L.I. Arkharova’s psychological and pedagogical competencies and long experience enabled to create the conditions for attracting the best teachers of Ryazan. Being rather a small city, when the teachers of the FSBEI of HE " Ryazan State University named for S. Yesenin" know the best of the best by sight, teach the potential teachers a worthy education and “see” the situation from the inside, close cooperation and interaction can be observed. Entering the lyceum, children individually reveal their potential being surrounded by care, warmth, love and attention to the personality of everyone.
Synovial Sarcoma of Vena Cava Inferior in a Child: an Unusual Presentation
Authors: Rascon Jelena , Tamulienė Indrė , Rascon Jelena , Monkevicius Martynas
Published: May 2020

We present a case of 3-year-old boy with monophasic synovial sarcoma which invaded the right atrium,
encircled vena cava inferior and dislocated femoral arteries. A tumor excision surgery was performed under
deep hypothermic circulatory arrest. The recommended treatment for this type of tumors is radical excision,
but since it was impossible to remove the whole tumor radiotherapy and chemotherapy was initiated. The
patient is followed-up every 6 months and is, 6 years after the surgery, in long-term remission with no signs
of disease progression.
The Menstrual Cycle Related Hormone Variations and Breast Cancer Risk: A Novel Theory
Authors: Xiaohui Liang , Xiaohui Liang , Taylor Nicholas , Fang Vixey , Zhang Xiao
Published: May 2020

Background: The cumulative and excessive exposures to estrogen contributing to increased risk of breast
cancer may be misleading.
Methods: We proposed a novel theory to highlight that exposure to unstable estrogen levels may play a
critical role in determining breast cancer risk among females as the change of endocrine environment may
pose a risky environment to breast tissues for carcinogenesis. Particularly, we considered the menstrual
cycle related estrogen variation (MCREV) as the primary hazard to breast cancer among females.
Results: To describe MCREV, its intensity was defined as the difference between the highest and the lowest
levels of estrogen within a menstrual cycle; its timing was defined as age at menarche and age at pregnancies
(i.e. timing of cessation of exposure to this hazard); and its frequency and duration can both be defined as
the total number of menstrual cycles, which is influenced by many factors including age of menarche, age
of menopause, average length of one menstrual cycle, and durations and number of pregnancies and
breastfeeding.
Conclusions: The proposed MCREV theory may identify women at high-risk of breast cancer at an earlier
age. The development of breast cancer might be weakened if suitable techniques to reduce the MCREV
become clinically available. This novel theory opens a new door in breast cancer prevention and
management.
Leiomiosarcoma of the Subcutaneous Tissue the Difficulties of Clinical Diagnosis: Description of a Case
Authors: Crisci Alessandro , Crisci Alessandro , Crisci Michela , D’Adamo Raffaele
Published: May 2020

Aims: Leiomyosarcomas are infrequent malignant tumors of smooth muscle, mainly derived from blood
vessels or viscera. Superficial leiomyosarcomas are rare soft tissue sarcomas resulting from the dermis or
subcutaneous tissue. They show a preference for proximal ends and tend to be slow-growing. They clearly
show different histological and prognostic characteristics depending on whether they are cutaneous or
subcutaneous.
Case Report: We reported the case of subcutaneous leiomyosarcoma resulting in the medial subinguinal
region of the right thigh in a 58-year-old female. Leiomyosarcoma is an entity whose clinical presentation
may appear non-specific, making diagnosis difficult. We discussed the case with a brief review of the
literature and the difficulties of a first approach clinical diagnosis.
Conclusion: In conclusion, a long period of patient follow-up is recommended to capture a subsequent
malignant progression of the disease.
En Bloc Capsulectomy with Implant Explantation in a High-Risk Patient with Breast Implant Illness: A Case Report
Authors: Irfan Zuhair , Siddiqui Aamir , Tepper Donna , Irfan Zuhair
Published: May 2020

En bloc resection with capsulectomy in breast implant surgery may be problematic and challenging, with
limited indications aside from Breast Implant Associated Anaplastic Large Cell Lymphoma [1, 2]. This is a
case report highlighting the technique and tools utilized intraoperatively in higher risk circumstances with
a 35-year-old female patient and her medical team requesting explantation with total capsulectomy as a
compassionate measure for a perceived contribution towards the patient’s uncontrolled hypertension of
unknown etiology [3].
Racjonalizacja procesu prawotwórczego w prezydenckich i semiprezydenckich ustrojach państw Afryki frankofońskiej
Authors: Jakubiak Łukasz
Published: May 2020

The paper deals with procedures rationalising the course of law-making proceedings in African states that have created their constitutional arrangements on the basis of the model developed in the Constitution of the Fifth Republic of France. In the French case, these mechanisms can be seen as one of the aspects of far-reaching rationalisation of the broadly understood parliamentary system of government, which was maintained (but with signifcant modifcations) in the Constitution of 1958. The author argues that the possibility of applying these constructions in Africa depends, at least to someextent, on the adopted system of government (presidentialism or semi-presidentialism), as well as on the one- or two-chamber structure of the parliament.
Specyfka osobowości osób nieletnich będących wychowankami domów dziecka oskarżonych o popełnienie przestępstw na tle seksualnym
Authors: Jałyszew Stanisław
Published: May 2020

Przestępstwa na tle seksualnym dość często są popełniane przez osoby nieletnie. Nieletni będący wychowankami domów dziecka, ze względu na warunki dorastania, dewiacje w wychowaniu, różnią się znacząco od swoich rówieśników z rodzin niepatologicznych. Śledztwo w podobnych sprawach wiąże się z pewnymi problemami. W artykule została opisana specyfka osobowości tej kategorii sprawców.
Świadczenia oświatowe samorządowej administracji świadczącej
Authors: Kurzyna-Chmiel Danuta
Published: May 2020

The local governments offers a crucial service to individuals by providing them with educational opportunities, care and social prevention programs. In our country, local governments carry out most public tasks in the feld of education. In fact, they are responsible for education in their respective territories. Educational needs are mainly satisfed by public (administrative) institutions run by these units, for example: schools, kindergartens, psychological and pedagogical counseling centers. However, local authorities have also a signifcant impact on the functioning of non-public schools and institutions and the type of services they provide.
Komentarz do przepisów prawa finansowego
Authors: Lavers Richard
Published: May 2020

W celu zapewnienia prawidłowo funkcjonującego wzrostu gospodarczego tradycyjnie stosowane są podatki i wydatki jako dwa główne narzędzia polityki fskalnej, które podlegają ograniczeniom ustawowym i konstytucyjnym. Jednakże na inﬂację, zatrudnienie i przepływ pieniędzy mogą mieć również wpływ regulacje prawne, które nie ograniczają środków służących do poboru podatków. Rozsądna polityka fskalna i prawo fskalne muszą uwzględniać wpływ regulacji prawnych na wyniki gospodarcze, co jest „oczywisty problemem, o którym się nie mówi”. Środki prawne, określane jako „ukryte podatki”, odgrywają coraz większą rolę w kierowaniu gospodarką USA. Ostatnie wyniki dotyczące analizy gospodarki USA wskazują na empiryczne dowody skutków ograniczających regulacje prawne w tym zakresie, a także wpływtych regulacji na innowacje. Oprócz tradycyjnie stosowanych podstawowych narzędzi polityki fskalnej, podatków i wydatków, polityka fskalna i prawo fskalne muszą uwzględniać wpływ regulacji prawnych i stosowanej polityki regulacyjnej na gospodarkę, inﬂację i przepływ pieniędzy przez system gospodarczy.
Przypadki znęcania się nad zwierzętami i reakcji na nie a etyka zawodowa lekarzy weterynarii: wątpliwości etyczno-prawne
Authors: Dzikowski Andrzej
Published: May 2020

Zachowanie lekarzy weterynarii – jako przedstawicieli zawodu zaufania publicznego – winno być zgodne z zasadami etyki zawodowej, w tym dotyczącymi reakcji na przypadki braku dobrostanu lub okrucieństwa wobec zwierząt. Celem pracy jest wskazanie punktów dyskusyjnych, takich jak, powiązane z możliwym znęcaniem się nad zwierzętami, normy prawne i wybory deontologiczne (a także ewentualne błędy), jak również niezgodność postępowania ze standardami etyki zawodowej. W pracy poddane analizie i zaprezentowane zostały wątpliwości i spory o charakterze normatywnym i moralnym w odniesieniu do różnych dziedzin działalności lekarzy weterynarii w zakresie ochrony zwierząt i okrucieństwa wobec nich. Przedstawione zostały postulaty deontologiczne i de lege ferenda, a także obserwacje z zakresu etyki zawodowej.