bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of hemoglobin F and A2 on hemoglobin A1c determined by cation exchange high-performance liquid chromatography
Authors: Can Murat , Güven Berrak , Demir Akca Ayse Semra
Published: September 2019

Background

The potential effect of increase in hemoglobin (Hb) A2and HbF on glycated hemoglobin (HbA1c) measurements were investigated using a high-performance liquid chromatography (HPLC) method compared with an immunoturbimetric assay.

Methods

Samples producing abnormal chromatograms during the measurement of routine HbA1ctesting with HPLC were further analyzed to characterize abnormal Hb variants. Patients were divided into three groups that had only high HbF (group 1), only high HbA2(group 2), and both high HbA2and HbF (group 3). HbA1cvalues of patients were re-assayed using the immunoturbidimetric method (Advia, Siemens Healthcare, Germany).

Results

HbA1clevels were significantly higher in all groups measured by immunoassay than in HPLC. We found a positive correlation between HPLC and immunoturbidimetry in the group 2 and a slight correlation in the group 1. There was no correlation between the two methods in group 3.

Conclusions

HbA1cmeasurement by HPLC method interfering with elevated HbA2and HbF, especially HbF, should be verified by an immunoturbidimetric method.
eEF1A2 exacerbated insulin resistance in male skeletal muscle via PKCβ and ER stress
Authors: Guo Meng , Li Yuna , Wang Yan , Li Zhenkun , Li Xiaohong , Zhao Peikun , Li Changlong , Lv Jianyi , Liu Xin , Du Xiaoyan , Chen Zhenwen
Published: September 2019

Recent studies raise the possibility that eukaryotic translation elongation factor 1 alpha (eEF1A) may play a role in metabolism. One isoform, eEF1A2, is specifically expressed in skeletal muscle, heart and brain. It regulates translation elongation and signal transduction. Nonetheless, eEF1A2’s function in skeletal muscle glucose metabolism remains unclear. In the present study, suppression subtractive hybridisation showed a decrease in Eef1a2 transcripts in the skeletal muscle of diabetic Mongolian gerbils. This was confirmed at mRNA and protein levels in hyperglycaemic gerbils, and in db/db and high-fat diet-fed mice. Further, this downregulation was independent of Eef1a2 promoter methylation. Interestingly, adeno-associated virus-mediated eEF1A2 overexpression in skeletal muscle aggravated fasting hyperglycaemia, hyperinsulinaemia and glucose intolerance in male diabetic gerbils but not in female gerbil models. The overexpression of eEF1A2 in skeletal muscle also resulted in promoted serum glucose levels and insulin resistance in male db/db mice. Up- and downregulation of eEF1A2 by lentiviral vector transfection confirmed its inhibitory effect on insulin-stimulated glucose uptake and signalling transduction in C2C12 myotubes with palmitate (PA)-induced insulin resistance. Furthermore, eEF1A2 bound PKCβ and increased its activation in the cytoplasm, whereas suppression of PKCβ by an inhibitor attenuated eEF1A2-mediated impairment of insulin sensitivity in insulin-resistant myotubes. Endoplasmic reticulum (ER) stress was elevated by eEF1A2, whereas suppression of ER stress or JNK partially restored insulin sensitivity in PA-treated myotubes. Additionally, eEF1A2 inhibited lipogenesis and lipid utilisation in insulin-resistant skeletal muscle. Collectively, we demonstrated that eEF1A2 exacerbates insulin resistance in male murine skeletal muscle via PKCβ and ER stress.
Letterkunde as kulturele ekologie in Die Bergengel (Carina Stander)
Authors: Meyer Susan
Published: September 2019

Die Bergengel (The Angel of the Mountain), with its striking nature centeredness, is characterised by poetical and lyrical use of language. This aspect is drawn into the ecocritical study of the novel in this article. Hubert Zapf’s theory on literature as cultural ecology, placed within the theoretical frame of material ecocriticism, supplies the foundation for this study. An ecocritical reading of Die Bergengel leads to uncovering a counter-discourse in the novel aimed at disrupting prevalent anthropocentric views on nature and environmental issues. Narrative events reveal the agentic power of nature and its dynamic influence on human conditions; the novel challenges the long taken-for-granted dominant position of humankind. The poetic language effectively functions in highlighting the interconnections between different forms of life where previously we had seen separations, suggesting more thoughtful interpretations of human-nonhuman-relations underlying the practices of environmental violence and exploitation the novel speaks of. Where the play with language and words is so directly connected with the ecocritical discourse, literature’s potential in bringing together the supposed separated spheres of culture (language) and nature becomes clear. Die Bergengel cogently voices the idea of the “reintegrative interdiscourse” which is central to Zapf’s viewing of literature as cultural ecology.
Multiplex Immunofluorescence on Fresh Frozen Tissue v1
Authors: Brewer Maya , Zhu Yuantee , Neumann Elizabeth , Gutierrez Danielle , Spraggins Jeff , De Caestecker Mark
Published: September 2019

Scope: To describe the procedure for multiple cycles of immunofluorescence on human kidney tissue embedded in carboxymethylcellulose. Expected Outcome: Kidney tissue sections that have been tagged with antibodies for imaging microscopy.
Antibody Purification and Labeling v1
Authors: Brewer Maya , Zhu Yuantee , Gutierrez Danielle , Spraggins Jeff , De Caestecker Mark
Published: September 2019

This protocol describes the process for antibody purification and subsequent labeling for direct immunofluorescence.
Collection and Post-Surgical Excision of Human Kidney Tissue through the Cooperative Human Tissue Network v1
Authors: Brewer Maya , Allen Jamie , Neumann Elizabeth , Fogo Agnes , Harris Raymond , Gutierrez Danielle , De Caestecker Mark , Spraggins Jeff
Published: September 2019

Scope: Obtain kidney tissue and metadata about tissue location within the whole kidney for storage and analysis. Expected Outcome: A portion of kidney tissue and a series of images that provide information about the original location of the smaller tissue.
Colony PCR v1
Authors: 董 宏亮
Published: September 2019

This PCR method can be used to screen for inserted target genes or DNA sequencing analysis.
Creation of low-oxygen conditions. v2
Authors: Yan Shengyi , 董 宏亮
Published: September 2019

We use Na2SO3 to create low-oxygen conditions in ourexperiment.
Relations Between Labour Party and Christian Churches in England at the End of XIX – the First Third of the XX cc.
Authors: Buturlimova Olha
Published: September 2019

The article traces the responses of the Church of England, Roman – Catholic Church and “free churches” on the development of the Labour Party. The author underlines that Labour party was assisted by those Christian churches. It is mentioned also that Labour Church and Ethic Church as Labour supporters too.

The article touches upon such problems as social inequality in British society, secularization of the working class in urban cotton towns and ports. Anglican Church’s help to the low-income working class is investigated also.

The author underlines that British Labour party was deeply influenced by Christian Socialism so it made its relations with Church of England closer. Chaplains supported the Labour party in their sermons, letters and church press. Such favour was especially crucial in rural areas where Labour party had lower election results in comparison with Liberal and Conservative parties.

The author analyses contribution of the “free churches” to the development of the Labour party. It is widely recognized that “free churches” are identified as traditional ally of the Liberal party. The author confirmed that “free churches” did not give wide electoral support to the Labour party but gave considerable amount of candidates who were active in trade unions, local Labour parties and in the British Parliament.

The author also considers that the Roman – Catholic communities mainly represented by Irish immigrants and their descendants as an important part of the wide social base of the Labour Party.

The author comes to conclusion that strong ties between Christian churches and the British Labour party help us to explain its program and election successes in the first third of the XX century.
Issues of establishing legal liability for offenses related to the diagnosis and human genome editing
Authors: Burtsev A. K. , Vasiliev S. A.
Published: September 2019

The global experience of giving treatment using human genome diagnostics and editing technologies in different countries shows different results. This sphere of public relations raises many disputes on a number of issues in the context of bad faith of those physicians who participate in carrying out the procedures under consideration. Unfortunately, wrongdoers in this area use modern technologies for their own sinister purposes. For the Russian Federation, the problem under consideration is not as urgent as for many more medically developed States. However, if such precedents take place abroad, with a high probability they should be expected in Russia. On this basis, it is necessary to review the legal regulation in terms of establishing penalties for offences in this area. The author analyzes the current normative legal regulation of domestic genetic engineering and gives some proposals for its reform.
The departure of the hero in a ship: The intertextuality of Beowulf, Cynewulf and Andreas
Authors: Leneghan Francis
Published: September 2019

This article identifies a new Old English poetic motif, ‘The Departure of the Hero in a Ship’, and discusses the implications of its presence in Beowulf, the signed poems of Cynewulf and Andreas, a group of texts already linked by shared lexis, imagery and themes. It argues that the Beowulf-poet used this motif to frame his work, foregrounding the question of royal succession. Cynewulf and the Andreas-poet then adapted this Beowulfian motif in a knowing and allusive manner for a new purpose: to glorify the church and to condemn its enemies. Investigation of this motif provides further evidence for the intertextuality of these works.Keywords: Old English poetry; Beowulf, Cynewulf; Andreas; Anglo-Saxon literature
Prescribing patterns of tramadol in hemodialysis patients
Authors: Saritha Manem , Mohan Pathapati Rama
Published: September 2019

Background: Pain is the most common complaint in hemodialysis patients. Tramadol had become analgesic of choice in these patients, and its prescription is increasing day by day. With this background, we evaluated the prescribing trends of tramadol in patients undergoing maintenance hemodialysis.Methods: A total of 70 prescriptions were audited to assess the prescribing trends of tramadol (usually prescribed as a combination of 37.5 mg tramadol and 325 mg of paracetamol two times a day). Included prescriptions were from both male and female patients above 18 years of age undergoing maintenance hemodialysis. Demographic, clinical and medication use were recorded from the patients.Results: The mean age of patients was 48±11.7 years, duration of dialysis 2.2±1.4 years. Tramadol consumptions were observed in 40/70 (56%) of patients. Majority of tramadol consumption was found in 30/40 (75%) males, 23/40 (59%) between 40-59 years and 28/40 (70%) undergoing two dialyses per week and 13/40 (32.5) were diabetics. During our exploratory analysis, we found that 15/40 (38%) of tramadol users, were concurrently prescribed with clonidine as add on antihypertensive. We noticed that the tramadol pill count during the preceding week was 81 in patients concurrently using clonidine and 139 in the patients who were not using clonidine (p>0.05).Conclusions: In our study, tramadol consumptions were observed in 56% of patients. We also noticed analgesic interaction between clonidine and tramadol.
Drug price control order: the impact on pharmacoeconomics
Authors: Shah Suchi M. , Singh Anil P. , Vachhani Parth K.
Published: September 2019

Background: The objective of the present study was to analyze the prices of metformin, losartan, atorvastatin, paracetamol and aspirin for the doses which are included in the list of Drug Price Control Order (DPCO) 2013.Methods: Current index medical specialties India, 37th year, April-July 2015 issue was used for analysis. The retail prices of the drugs in INR were tabulated in Microsoft Office Excel 2013. The prices of the above listed drugs were compared with prices of DPCO 2013 for the same doses of drugs. The analysis of drugs costing more than the prices listed in the DPCO with the margin of the difference in percentage was carried out.Results: Out of 25 brands of metformin 500 mg tablet, 11 (44%) brands had price higher than listed in DPCO 2013. Similarly, prices for losartan 25 mg and 50 mg tablets, 8 (25%) out of 32 and 11 (31.42%) out of 35 were higher respectively. For atorvastatin 5 mg and 10 mg tablets, 2 (9.52%) out of 21 and 8 (13.55%) out of 59 brands had higher prices. For paracetamol 500 mg tablet, 12 (63.15%) out of 19 brands were priced higher than DPCO list. For aspirin 100 mg tablet and 325 mg tablet, 3 (100%) out of 3 brands and 1 (100%) out of 1 brand had higher prices.Conclusions: Many of the brand formulations have higher prices than the DPCO 2013 issued by government of India. The clinicians prescribing these drugs should be aware of these brand formulations to reduce the cost of the drug therapy.
Clinical study of asymptomatic deep vein thrombosis in patients with varicose veins of lower extremities
Authors: M. Basavarajappa , G. S. Anantharaju , G. Deepak
Published: September 2019

Background: The main aim is to study the association between asymptomatic deep vein thrombosis (DVT) in patients with varicose veins in different gender and age groups. Secondly, to study the risk of developing DVT in patients having superficial venous thrombophlebitis (SVT) with varicose veins and finally to study the clinical correlation of clinical, etiological, anatomical and pathological (CEAP) classification with DVT in patients with varicose veins.Methods: Patients presenting to department of General surgery at SS Institute of Medical Science and Research Centre during the period from June 2017 to June 2019 with varicose veins of lower limbs and without clinical signs of DVT were included in this study. Patients were categorised according to CEAP classification. All patients were subjected to duplex scanning of lower limbs to look for presence of SVT and DVT.Results: In our study, 73% patients were males and 27% patients were females. Maximum patients were in age group of 40-60 years.16 patients had DVT, 38 patients had SVT, 166 patients belonged to C2 and 56 patients belonged to CEAP class C3 and beyond.Conclusions: There is a strong association between varicose veins and asymptomatic DVT .The presence of SVT is not a risk factor for concomitant DVT in varicose vein patients. Clinical presentation with C3 or more CEAP grade is one of the potential risk factors for concomitant DVT in vari­cose vein patients.
Angiosome based revascularization for diabetic foot ulcer
Authors: Hossny Ahmed M. , S. Eldesouky Mahmoud , Abdellatif Mohamed A.
Published: September 2019

Background: The purpose of this study was to analyze the clinical benefit in wound healing and limb preservation after infrapopliteal endovascular revascularization guided by an angiosome model of perfusion in the healing process of diabetic foot ulcers.Methods: This is a prospective controlled study was conducted on 60 patients with critical lower limb ischemia in the form of diabetic foot ulcer and/or gangrene. The study period started from August 2017 until February 2019. Patients included in the study were essentially attending the Vascular Outpatient Clinic at Menoufia University Hospitals and Nasser Institute for Search and Treatment at Cairo treated by infra-popliteal angioplasty.Results: The 60 patients of our study who underwent successful infra-popliteal angioplasty we found that after six months 18 patients in the direct group A (85.71%), 9 patients in indirect group B (42.85%) and 17 patients in combined group C (94.44%) showed complete healing of their wounds and that 18 patients in group A (85.71%), 15 patients in group B (71.42%) and 17 patients in group C (94.44%) have their limbs salvaged total 50 patients (83.33%).Conclusions: We concluded that dilation of angiosome target artery plus any other significant tibial artery lesions should be considered and indirect revascularization should not be denied with acceptable result over time.
Negociantes e capitalistas: transformações das práticas mercantis no	Brasil imperial, em meados do século XIX, Ouro Preto, Minas Gerais
Authors: Andrade Leandro B. de
Published: September 2019

O estudo analisa alguns elementos das práticas de mercado, em transformação durante o século xix, principalmente os instrumentos do ofício dos comerciantes, as formas de investimentos e as instituições financeiras. O foco são os agentes mercantis de Ouro Preto, capital da província de Minas Gerais, onde as possiblidades de acumulação eram restritas por sua posição periférica no mercado interno brasileiro. O objetivo é demonstrar, no entanto, que o caráter urbano do comércio e da riqueza dessa região acompanhava o processo de modernização e institucionalização pelo qual passava a economia e o Estado nacional. Dessa forma, a abordagem microanalítica mostrou-se eficaz ao revelar quando tais transformações ocorreram e como foram ativadas pelos negociantes e capitalistas locais.
Influence of swirl, tumble and squish flows on combustion characteristics and emissions in internal combustion engine-review
Authors: KAPLAN Mahmut
Published: September 2019

This study gives an overview
of available literature on flow patterns such as swirl, tumble and squish in
internal combustion engines and their impacts of turbulence enhancement,
combustion efficiency and emission reduction. Characteristics of in-cylinder
flows are summarized. Different design approaches to generate these flows such
as directed ports, helical ports, valve shrouding and masking, modifying piston
surface, flow blockages and vanes are described. How turbulence produced by
swirl, tumble and squish flows are discussed. Effects of the organized flows on
combustion parameters and exhaust emission are outlined. This review reveals
that the recent investigations on the swirl, tumble and squish flows are
generally related to improving in-cylinder turbulence. Thus, more experimental
and numerical studies including the impacts of this organized flows on
turbulence production, combustion behavior and pollutant formation inside the
cylinder are needed.
Classification, preparation process and its equipment and applications of piezoelectric ceramic
Authors: Zhao Quanlu , Zhao Juntao , Tan Xiangfeng
Published: September 2019

The so-called piezoelectric ceramic is a piezoelectric polycrystal, a functional ceramic material capable of inter-converting mechanical energy and electric energy. It belongs to inorganic nonmetallic materials. So far, the most widely used piezoelectric ceramic materials have both good piezoelectricity and ferroelectricity through the substitution and doping in a wide range to adjust its properties to meet the diﬀerent needs of zirconium titanium lead (PZT) and its composite materials. Piezoelectric ceramic is also one of the prevailing piezoelectric materials, accounting for about 1/3 of the entire functional ceramic materials. It is mainly used for transducers, sensors, resonators and drives.
PEDAGOGICAL REQUIREMENTS FOR THE IMPLEMENTATION OF DIFFERENTIATED APPROACH IN TEACHING ELEMENTARY SCHOOL CHILDREN
Authors: Dulmukhametova Gulnara Faridovna , Sirazieva Zarina Nailevna , Gali Gulnara Faritovna , Nicolaevna Usova Svetlana , Shamsutdinova Dilbar Valievna
Published: September 2019

Purpose of the Study: The article describes the authors’ view on the model of the implementation of a differentiated approach in the training of elementary school children.

Methodology: In the research, the authors identify and systematize the pedagogical requirements for ensuring the sex differentiation in education of elementary school children, together forming a meaningful model for implementing a gender approach to the educational process of primary school and including gender education for students, teachers, and parents. The authors analyze the category of sex differentiation in domestic and foreign pedagogy.

Result: The authors theoretically describe the problem of implementing a differentiated approach in teaching elementary school children, and also substantiate the experimental work on testing the effectiveness of pedagogical conditions that interconnect and complement each other, forming a dynamic system that ensures the effective organization of the sex differentiation of elementary school children.

Application and Novelty: Presented pedagogical requirements and model of a gender approach to the educational process can solve the age and gender problems of elementary school children and harmonize their relationships. Data of the article can be used not only in the educational process of elementary school, but also at the lessons of such subjects as "Pedagogical psychology", "Developmental psychology", and "Differential psychology" at the university. These requirements give the opportunity
VALUES AND ANTI-VALUES IN FIGURATIVE PHRASEOLOGICAL UNITS IN THE RUSSIAN AND GERMAN LANGUAGES
Authors: Andreyeva Yelena Anatolyevna , Korneva Inna Germanovna , Sakhibullina Kadria Azatovna
Published: September 2019

Purpose of the Study: The article discusses values and anti-values in the figurative phraseological units of the Russian and German languages. The object of the research is phraseological units of the Russian and German languages that have similar and specific images. The subject of the research is hedonistic and material-utilitarian values and anti-values contained in the Russian and German figurative phraseological units.

Methodology: The relevance of the study is due to the spiritual needs of modern society. The analysis of phraseological units in the axiological aspect is motivated by the anthropological orientation of modern linguistics where the language is considered in close connection with the consciousness and thinking of a person, their spiritual world, values, and anti-values. The research methods are the following: descriptive method, analysis of lexicographical interpretations, and etymology of the Russian and German phraseological units; the method of component analysis to research the structure of meaning of studied units; the method of conceptual and interpretative analysis.

Results: Hedonistic and material-utilitarian values and anti-values are represented by the Russian and German phraseological units that have similar images in their composition, which is due to the common source of the origin of phraseological units, and specific images associated with the Russian and German cultures.

Application: Research results can be helpful for the German language training and professional activities of translators and linguists.
INFLUENCE OF LOCUS OF CONTROL AND GENDER ON PROFESSIONAL JUDGMENT
Authors: Cheisviyanny Charoline , Dwita Sany , Helmy Herlina
Published: September 2019

Purpose of this study: This study aims to prove the influence of locus of control (LoC) and gender on professional judgment.

Methodology: The population was professional accountants in Padang, represented by public accountants and accounting lecturers. The sampling technique used was the purposive sampling method. Totally, 69 respondents were selected as a sample in this study. The research data was obtained through questionnaires. Data were analyzed using the independent t-test.

Main Findings: The results of this study are: (1) There is no difference between male accountants and female accountants in giving judgments; (2) The second hypothesis (H2) cannot be concluded, because of the great differences in sizes between both the groups; (3) There is no difference among male accountants with internal and external LoC, and female accountants with internal LoC in giving judgments.

Application/Implication: The results are interesting since all the hypotheses were rejected. These findings implied that LoC and gender do not influence professional judgment because accountants have a code of ethics that guides them in making judgments. It suggests for further researches to add other variables such as culture or religiosity.
THE RELATIONSHIP BETWEEN ENVIRONMENTAL PERFORMANCE AND THE EXTENT OF ENVIRONMENTAL DISCLOSURE
Authors: Purwantini Cornelio , Faisal Faisal , Januarti Indira , Dwiatmoko Ignatius Aris
Published: September 2019

Purpose of this study: This study examines the relationship between environmental performance and the extent of environmental disclosure.

Methodology: The sample of this study consists of 35 high profile companies. The environmental performance is measured based on the results of the assessment of PROPER and the extent of environmental disclosure index by using GRI checklist items. This research applies content analysis, descriptive, and inferential statistical analyses.

Main Findings: The result shows that the extent of environmental disclosure, on an average is low (22.5%). Mining companies provide the highest environmental disclosure (58.2%) followed by chemicals (21.4%), utilities (19.0%), pulp and papers (16.5%), industrial (11.0%), and oil and gas (4.2%). The analysis also presents that environmental performance does not affect the level of environmental disclosure.

Implications: This result suggests that high environmental performance may not encourage companies to communicate more environmental issues. This finding indicates that motivation for a company to disclose environmental information is not always based on the legitimacy perspectives, but might be an accountability form.
EMPOWERING STUDENTS TO BECOME EFFECTIVE LEARNERS THROUGH ACTIVITY BASED LEARNING
Authors: Kanchana Dr. S , Patchainayagi Dr. S , Rajkumar Dr. S
Published: September 2019

Purpose of the study: Activity based learning helps students to learn actively in classroom and it also provides ample scope for experimental learning. Students are to be provided opportunities and optimum learning environment to explore their knowledge and skills. It would broaden the understanding of concepts and theories in their core premises. It enhances the learning process and the students as active learners.

Methodology: Interactive learning strategies are categorized as individual learning and group learning strategies. Individual activities may include flipped learning, polling answers and questions. Group activities include pair and share strategy, inspire and initiate scenarios. 

Main Findings: Interactive learning strategies, E-Learning and M-Learning are preferred modes for the students, promotes the cognitive level of the learners, achieved learning objectives. It is essential to suggest and design innovative learning practices.

Implications: Higher education institutions and even schools are using various enhanced interactive learning practices, educational apps and M-Learning techniques. These activities enhance the student engagement in the classroom. By implementing activity based learning practices, learners become investigators and strive to make best real time decisions for different scenarios.

Novelty/Originality of this study: Enhanced learning strategies promotes cooperative learning and efficient for large group of learners.
The evaluation of completeness of examination of eye-ground in ambulatory conditions in pregnant women on the basis of results of their interviewing
Authors: Isaeva Yu. G. , Sabgayda Tamara P.
Published: September 2019

The pregnancy and delivery can provoke development of retinal detachment in women in the presence of pathological alterations of eye-ground. The rapid development of ophthalmology and amelioration of material and technical resources of medical organizations processing out-patient reception permit hoping for comprehensive examination of eye-ground of all pregnant women. The study was carried out with purpose to evaluate completeness of examination of eye-ground of pregnant women in out-patient conditions. The methods. The questionnaire survey was organized concerning women at the last month of pregnancy being for treatment in department ofpregnancy pathology in a certain maternity hospital under large multifield hospital of Moscow in 2014-2015. The analysis was applied to answers of 481 women concerning completeness of their examination by ophthalmologist at out-patient stage of observation. The analysis of grounds for alertness of ophthalmologists concerning risk of retinal detachment was implemented on the basis of data from state statistical reporting form № 12 about morbidity of Russian population (including girls aged from 15 to 17 years) with eye diseases and its adnexa (2005-2015), myopia (2005-2014), degenerative myopia and retinal detachment with rupture (2014-2015). Conclusions. The study established that every ninth women (11.2%) miss visiting to ophthalmologist during pregnancy; in all the rest, condition of periphery of eye-ground was not examined properly i. e. examination of eye-ground under mydriasis is implemented in 41.2% of cases and in case of one-time visit (54.2%) only in 33.7% of cases. The absence of mandatory examination of eye-ground at wide pupil of pregnant women by ophthalmologists of primary medical care level deprive of any sense recommendation about twice visit to oculist during pregnancy period. The observed deterioration of ophthalmic health ofpopulation provoke no interest in oculists ofprimary medical care level to increasing of alertness related to risk of retinal detachment during natural delivery. There are grounds to expect further increasing of development of retinal detachment in women during natural delivery.
The requirements in medical rehabilitation of adult population of different age groups in hospital conditions
Authors: Prilipko Nina S.
Published: September 2019

The study was carried out to determine requirements of adult population of Russia in medical rehabilitation in hospital conditions depending on age groups. To determine requirements of country population in medical rehabilitation in hospital conditions the age-specific indicators derived from data massive from three territories were standardized on population and morbidity in Russia in 2010. The number of hospitalized patients being in need of medical rehabilitation in hospital conditions was determined as indicator characterizing requirements of population in medical rehabilitation in hospital conditions. The age-specific requirements of adult population in medical rehabilitation in hospital conditions was determined and analyzed on the basis of number of cases of annual hospitalization for medical rehabilitation in hospital conditions according main classes and particular diseases. The largest number ofpatients being in need of medical rehabilitation in hospital conditions goes to elder age groups 60-69 years (874.7 cases per 10 000 of population) and 70 years and older (1346.3 cases per 10 000 of population). The least number of this kind of patients goes to age group of 18-29 years (106.2 cases per 10 000 of population). The proposed calculated number of cases of hospitalization of adult population for medical rehabilitation in hospital conditions can be implemented by executive authorities of subjects of the Russian Federation in health care sector of any territory for determining requirements ofparticular region in medical rehabilitation with consideration for age structure of population.
The health of pregnant female migrants: analysis and possibilities of management
Authors: Artyukhov I. P. , Li-Gi-Ru S. Yu. , Gorbach Natalya A. , Kapitonov V. F. , Tskhay V. B.
Published: September 2019

The analysis of the results of complex study of health ofpregnant female migrants demonstrated that their health condition is significantly worse than in comparison group. The most of female migrants suffered from complications during pregnancy and delivery. The percentage of newborns delivered by female migrants without pathologic manifestations was 1.3 times less in comparison with similar percentage in women from comparison group. The developed situation is in many ways is caused by more unfavorable conditions of work and life of female migrants. Besides, it was established that percentage of female migrants without observation in maternity clinic was 19.7 times higher the similar percentage of women from comparison group. The registration prior to 12 weeks ofpregnancy was marked only in every forth female migrant. The percentage of female migrants with biochemical screening applied was three times lower. The analysis of medical social problems ofpregnant female migrants permitted to develop proposals related to management of their health at the expense of amelioration of medical social care including number of organizational, social and medical activities. The experts determined priorities in realization of proposed activities. The developed activities can be used as a background of program on health support of pregnant women from families of migrants as am integral part ofprograms ofpopulation health support.
The integral approach to evaluation of heath condition of workers of hazard industries
Authors: Yudina T. V. , Saarkoppel Lyudmila M. , Kryuchkova E. N.
Published: September 2019

The methodical approach to evaluation of health condition of persons working in unfavorable conditions of industrial enterprises based on detection of degree of correlation relationships between indicators of homeostasis of organism is developed. The proposed integral indicator - correlation adaption coefficient (ККА) - permits determining degree of adaptability of examined contingents to impact of unfavorable factors and to establish time-period of development of risks of health disorders and to timely determine and differentiate directions of preventive activities.
The role and possibilities of health centers in prevention and treatment of extra body mass and obesity
Authors: Lobykina Elena N. , Maklakova T. P. , Tatarnikova I. S.
Published: September 2019

The analysis of results of examination of 2569 visitors of health center was carried out. The study of nutrition status of242 women with different body mass revealed surplus of intake of fats, carbohydrates, caloricity of day diet in persons with obesity and tendency of its increasing as far as body mass increases. On the basis of characteristics of structure of diet the program «School of rational diet» is developed. The comparison of laboratory, diagnostic and resource possibilities of health center with algorithm of treatment of patients with surplus body mass and obesity established large possibilities of health center not only in diagnostic (examination of diet and metabolic status) but in complex treatment of patients with different body mass. These possibilities include behavioral (development of motivation to change life-style), non-medicinal (diet therapy) and medicinal therapy. At the expense of group and individual prevention counseling in «School of rational diet» the implementation of such an approach promoted decreasing of body mass during a month (on 2.18±1.28 kg) in 64.4% of listeners of «School of rational diet».
The treatment of tuberculosis in labor migrants: proposals on development of alternative financial organizational mechanism
Authors: Sergeev Boris I. , Kazanets I. E. , Mukhamadiev D. M.
Published: September 2019

Purpose. The high level of labor migration necessitates development of financial organizational mechanism ensuring diagnostic and treatment of tuberculosis among migrants. Above all, it concerns such countries as Russia where treatment of tuberculosis is provided at the expense of budget sources. The position of Russian lawmaker consists in development of voluntary medical insurance not including number of infectious diseases that makes necessary development of alternative suggestions. Methodology. The article presents review of results of empirical studies concerning participation of migrants in programs of voluntary medical insurance. The legal regulations and practice of medical care support of migrants in number of countries Russia included is reviewed too. Results. The questionnaire data testify limited access of migrants to system of voluntary medical insurance. In the countries receiving migrants treatment of tuberculosis is organized at the expense of state resources even in case of limitations of access to other types of medical care. In Russia these limitations does not cover citizen of Belarus. Practical significance. On the basis of this precedent establishment of the interstate foundation of medical insurance is proposed for covering all CIS countries' Within the framework of this foundation national contributions will support financing of treatment of tuberculosis of citizen of corresponding countries residing temporarily in Russia.
The development of criteria, indices and indicators and of medical care quality for patients with syndrome of diabetic foot in out-patient practice
Authors: Udovichenko Oleg V. , Berseneva E. A. , Meshkov D. O.
Published: September 2019

The special techniques of evaluation of every single disease are required for assessing quality and effectiveness of treatment in out-patient practice. The purpose of study was development of criteria, indices and indicators of evaluation of quality of out-patient medical care of patients with syndrome of diabetic foot. The technique of literary searching and practice analysis were applied to develop criteria, indices and indicators for evaluating structure, processes and results of treatment. The evaluation of quality of result requires more complicated techniques of data collection as opposed to indices of quality of structure and processes. The developed indices can be also applied in evaluating effectiveness of treatment of other diseases with chronic course though curable in the main.
The sociological approach to analysis of state of system of mandatory medical insurance and perspectives of its development
Authors: Kozhevnikov Andrey A.
Published: September 2019

The article considers scientifically substantiated sociological approach to development of socially oriented policy related to medical insurance and health care. Specifically, actual condition and problems of medical insurance is captured. The new system of medical social co-financing based on application of social economical methods of motivation is proposed with purpose of ensuring observance of healthy life-style by population and minimization of preventable losses. The shortcomings of actual system of mandatory medical insurance are enumerated and means to rectify them are proposed. At that, main attention is paid to searching for social mechanisms which combined with administrative measures can significantly increase quality of medical services and simplify character of relationships occurred apropos of this. The main components of the system of medical social co-financing and ensured positive possibilities achieved are emphasized.
The evaluation of dynamics of pollution of atmospheric air by stationary sources in the regions of the Republic of Bashkortostan
Authors: Askarov R. A. , Askarova Zagira F. , Karelin A. O.
Published: September 2019

The article presents the results of retrospective analysis of dynamics, structure, total volume of discharges of polluting substances into atmosphere from stationary sources in the regions of the Republic of Bashkortostan. The study used data from official state statistical reports of the territorial agency of the Federal service ofpublic statistics concerning the Republic of Bashkortostan “2TP- Air” in 2000-2012. It is established that in the regions of the Republic during number of last years intensive anthropogenic chemical pollution of atmospheric air is observed. In connection with that occurrence, a number of urgent measures concerning safety of atmospheric air from anthropogenic chemical pollution is required.
On medical insurance: considerations based on foreign experience
Authors: Yargin Sergey V.
Published: September 2019

The health care organization in Russia is similar to the same in Great Britain where exists public medical care system. At the same time, Russian health care, being insurance, bear resemblance with German health care. The significant characteristic of insurance medicine in Germany is availability of mechanism ofprice ofpoint that is shortly discussed in this article. The application of this mechanism leads to that in overall country the price of medical service is approximately the same independently of insurer. Accordingly, most of private medical practitioners and medical organizations receive all insured patients. The similar mechanism can successfully function only on the assumption of conscientiousness and higher level of professional knowledge of physicians who are not to prescribe pharmaceuticals and diagnostic procedures without sufficient indications. The adoption of mechanism ofpoint price by Russian health care would permit to redirect part of patients insured by mandatory medical insurance to private medical centers and private medical practitioners.
The implementation of program of development of health care of the Russian Federation in the theoretical and practical center of medical care of children of the Moscow health Department
Authors: Prityko Denis A.
Published: September 2019

The article considers organizational approaches to improvement of therapeutic care in the scientific practical center of medical care of children. The expediency of broad implementation of laser therapy at all stages ofmedical services rendering from clinical diagnostic center to center ofpalliative care of children. The results are presented concerning practical application of laser therapy in children oncology and under number of other diseases. The inclusion of laser medicine into priority direction of development of high-tech medical care in the Russian Federation is recommended.
The structure of working timetable and work measurement of medical nurse of general practitioner in conditions of municipal polyclinic
Authors: Kalininskaya Aleftina A. , Gadzhieva L. M.
Published: September 2019

The article presents form of work of medical nurse of general practitioner in conditions of total transition of municipal polyclinic at general medical practice. The results of study of work measurement of medical nurse of general practitioner in the new conditions with organization of independent medical nurse reception.
The organization of high-tech medical care of patients with ischemic heart diseasein the Far East federal region in 2004-2013
Authors: Bogachevskaya Svetlana A. , Bogachevskiy A. N. , Kapitonenko N. A.
Published: September 2019

To determine both perspectives of development of high-tech medical care in Russia and actuality of possible restructuring of system of cardio-surgery care of population it is appropriate to evaluate condition of surgical and intervention treatment of ischemic heart disease i the country and regions using the example of the Far East federal region. The analyzed indices were calculated for 100 000 of adult population. In Russia, during last decade, total common morbidity of ischemic heart disease increased up to 13.25±0,11% (n ± m) and primary morbidity factually doubled. In the Far East region indices increased up to 21,34 ± 0,13% and 67,33 ± 0,15% correspondingly. In Russia, the number of patients after coronary bypass surgery in increased up to 3.3 times (percentage of patients after ischemic heart disease surgery decreased on 42.5%) and number of patients with endovascular correction increased up to 7.8 times (their percentage increased up to 37.2%). In the Far East region increasing of coronary bypass surgery increased in 12.4 times, endovascular procedures - in 32.1 times. In Russia from 2005 lethality during direct myocardium re-vascularization surgery decreased on 21.6% and in case of endovascular interventions increased up to 2.1-2.9 times, including planned operations. The dynamics of most analyzed indices corresponds to international tendencies. However, the level of coronary surgery in Russia is still significantly lower than in the developed countries of Europe and America. In the Far East region, in 2013 situation with coronary surgery looks more reassuring than in 2004-2005 when it factually stopped developing. The health care authorities are to implement in the regions more elaborated analysis ofepidemiological indices with the purpose to develop effective activities concerning indices' amelioration; to standardize evaluation of lethality in case of surgery intervention; to adjust national standards of medical care under ischemic heart disease according international standards.
The sanitary hygienic characteristics of labor conditions in production of polyesters of terephthalic acid
Authors: Karamova L. M. , Krasovskiy V. O. , Basharova G. R. , Vlasova Natalya V.
Published: September 2019

The hygienic physiological evaluation of labor conditions of workers of main professions of production of phtalates was carried out. It is established that leading hygienic factor is chemical one with exceeding of MPC of terephthalic acid in 1.5-28 times. The overall evaluation of labor conditions of machinery operators corresponds to degree III - 3.3.
The evaluation of quality of medical care and labor process according results of survey of physicians
Authors: Evstigneev S. V. , Vasilyev Valery V.
Published: September 2019

The article presents results of sociological survey of opinions of physicians concerning quality of medical care and working process in the N.N. Burdenko Penza regional clinical hospital. The factors mainly impacting these appraisals. The survey results testify alteration in positive way the opinions of physicians concerning this problem as following increasing of level of organization of medical care in hospital.
The analysis of mortality of malignant neoplasms of population in the Republic of Bashkortostan (2002-2014)
Authors: Askarov R. A. , Karelin A. O. , Askarova Zagira F. , Sharipova I. A.
Published: September 2019

The article presents the results of analysis of dynamics and structure of mortality of malignant neoplasms of population of the Republic of Bashkortostan in 2002-2014. The results were calculated according data from table C51 "The distribution of the deceased by gender, age groups and causes of death" of Bashkortostan. To calculate statistical indices parametric, non-parametric and time series techniques were applied. On the whole, the dynamics of indices is comparable with national one i.e. insignificant decreasing of mortality is observed to 2014. The analysis testifies that during all analyzed both the "raw" and standardized mortality indices per 100 000 in average were higher in Russia than in the Republic ofBashkortostan. However, in the Republic of Bashkortostan, both in males and females increasing of mortality of malignant neoplasms of many localizations is detected. According prognosis estimates, decreasing of mortality of neoplasms in population of the Republic of Bashkortostan is possible.