bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline
Authors: Santomasso Bianca D. , Nastoupil Loretta J. , Adkins Sherry , Lacchetti Christina , Schneider Bryan J. , Anadkat Milan , Atkins Michael B. , Brassil Kelly J. , Caterino Jeffrey M. , Chau Ian , Davies Marianne J. , Ernstoff Marc S. , Fecher Leslie , Funchain Pauline , Jaiyesimi Ishmael , Mammen Jennifer S. , Naidoo Jarushka , Naing Aung , Phillips Tanyanika , Porter Laura D. , Reichner Cristina A. , Seigel Carole , Song Jung-Min , Spira Alexander , Suarez-Almazor Maria , Swami Umang , Thompson John A. , Vikas Praveen , Wang Yinghong , Weber Jeffrey S. , Bollin Kathryn , Ghosh Monalisa
Published: November 2021

PURPOSE

To increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events (irAEs) in patients treated with chimeric antigen receptor (CAR) T-cell therapy.

METHODS

A multidisciplinary panel of medical oncology, neurology, hematology, emergency medicine, nursing, trialists, and advocacy experts was convened to develop the guideline. Guideline development involved a systematic literature review and an informal consensus process. The systematic review focused on evidence published from 2017 to 2021.

RESULTS

The systematic review identified 35 eligible publications. Because of the paucity of high-quality evidence, recommendations are based on expert consensus.

RECOMMENDATIONS

The multidisciplinary team issued recommendations to aid in the recognition, workup, evaluation, and management of the most common CAR T-cell–related toxicities, including cytokine release syndrome, immune effector cell–associated neurotoxicity syndrome, B-cell aplasia, cytopenias, and infections. Management of short-term toxicities associated with CAR T cells begins with supportive care for most patients, but may require pharmacologic interventions for those without adequate response. Management of patients with prolonged or severe CAR T-cell–associated cytokine release syndrome includes treatment with tocilizumab with or without a corticosteroid. On the basis of the potential for rapid decline, patients with moderate to severe immune effector cell–associated neurotoxicity syndrome should be managed with corticosteroids and supportive care. Additional information is available at www.asco.org/supportive-care-guidelines .
The Conservation Treatment of the Bark of Wooden Sculpture
Authors: Kim Young Mok , Han Ye Bin , Shin Jeong Ah , Cha Sun Min , Kwon Hee Hong
Published: November 2021

The ‘artist’s intention’ plays an important role in the conservation process of contemporary art. Accordingly, the information on artworks owned by the artist, their bereaved family members, and foundations that have decision-making power is important. The artist’s interview is the kind of data that can clear ‘artist’s intentions’ to ensure reliable conservation treatment can be carried out even after the artist’s death. Therefore, this study attempted to use information from the artist’s interview on the type of wood in the manufacture of the filler required for lifted and separated bark conditions in the conservation process of wooden artwork in the National Museum of Modern and Contemporary Art. While the conservation treatment resulted in the stable preservation of the bark of artwork, an analysis of the wood confirmed that the information in the artist’s interview was not true. Consequently, we suggest that attention must be paid toward the information provided by artist, their bereaved families, etc. Based on the result of this study, this is also expected to help preserve upcoming artworks with similar bark conditions.
Study on Scientific Analysis about Red Pigment And Binder - The Korean Ancient Red Pottery -
Authors: Lee Ui Cheon , Park Jung Hae , Lee Je Hyun , Kim Soo Chul
Published: November 2021

From the collection of the National Kimhae Museum, qualitative analyses using microscopic observation, SEM-EDS, Raman spectroscopy, FT-IR-ATR spectroscopy, and GC-MS were conducted on three burnished red potteries—Jeoksaekmaoyeonwa burnished red pottery (Neolithic age red pottery), Dandomaoyeonwan burnished red pottery(Bronze age red pottery) and Jeoksaekmaoyeongajimun burnished red pottery(Bronze age red pottery)—to investigate the components of the red pigments and the binder. After the layers of the primer were separated from the red surface, crystals of red pigment particles and minerals were found on the red surface. Through SEM-EDS, Raman estimates that the red pigment is Among soil pigments with iron oxide(Fe2O3) as the main color development source, Red Ocher(Fe2O3). A band characteristic of the Urushiol polymer was detected in the FTIR-ATRspectra(4000∼600cm-1), GC-MS analysis confirmed the presence of the benzenemethanol-2-prophenyl, 4-heptylphenol, 1-tetracecanol, heptafluorobutyric texidecane, all of which are the ingredients of the directional structure of the lacquer present in the red layer. Therefore, it seemed that the three burnished red pottery: Jeoksaekmaoyeonwan pottery(Neolithic age burnished red pottery), Dandomaoyeonwan pottery(bronze age burnished red pottery) and the Jeoksaekmaoyeongajimun pottery(bronze age burnished red pottery) made by mixing minerals and Red Ocher(Fe2O3), with lacquer.
Semiconducting polymer gain media for optical amplifiers and lasers
Authors: Χελιώτης Γεώργιος
Published: November 2021

Τα ημιαγώγιμα πολυμερή προσελκύουν έντονο ενδιαφέρον ως καινοτόμα μέσα ενίσχυσης για συσκευές όπως λέιζερ και οπτικοί ενισχυτές. Ένας σημαντικός μελλοντικός στόχος σε αυτό το πλαίσιο είναι η υλοποίηση μιας διόδου λέιζερ πολυμερούς στερεάς κατάστασης. Τέτοιες οργανικές δίοδοι λέιζερ έχουν τη δυνατότητα να φέρουν επανάσταση στην αγορά των λέιζερ ημιαγωγών, προσφέροντας εξαιρετικά ευέλικτες και φθηνές πηγές λέιζερ που μπορεί τελικά να ανταγωνιστούν τα ανόργανα λέιζερ σε μεγάλο αριθμό πεδίων.Αυτή η διατριβή περιγράφει τα αποτελέσματα μιας λεπτομερούς μελέτης των ιδιοτήτων ενίσχυσης και δράσης λέιζερ μιας σειράς υλικών που ανήκουν στην οικογένεια ημιαγώγιμων πολυμερών πολυφλουορενίου. Αποτελεσματική, χαμηλού ενεργειακού κατωφλίου εξαναγκασμένη εκπομπή επιδεικνύεται στην μπλε, πράσινη και κόκκινη φασματική περιοχή μέσω μετρήσεων ενισχυμένης αυθόρμητης εκπομπής σε επίπεδους ασύμμετρους οπτικούς κυματοδηγούς. Διερευνώνται λεπτομερώς τα χαρακτηριστικά ενίσχυσης των κυματοδηγών. Αποδεικνύεται ότι αυτές οι δομές παρουσιάζουν μεγάλες καθαρές οπτικές απολαβές , μεγάλες διατομές ενίσχυσης και πολύ χαμηλούς συντελεστές απωλειών εξασθένησης διάδοσης. Ευρεία ρύθμιση του μέγιστου μήκους κύματος ενίσχυσης κυματοδηγού επιδεικνύεται μέσω του ελέγχου των επιτρεπόμενων τρόπων διάδοσης των δομών ή με την ενεργή τροποποίηση της σύνθεσης των μέσων ενίσχυσης. Αυτά τα αποτελέσματα υπογραμμίζουν το ευρυζωνικό κέρδος που είναι προσβάσιμο με τα υλικά που μελετήθηκαν και, γενικά, καθιερώνουν τα πολυμερή με βάση το φλουορένιο ως ιδιαίτερα ελκυστικά μέσα υψηλής απολαβής για την κατασκευή πολυμερών λέιζερ στερεάς κατάστασης που εκπέμπουν σε μήκη κύματος σε όλο το ορατό φάσμα.Με βάση αυτά τα ευρήματα, υλοποιούνται επιτυχώς πολύ συμπαγή, πλήρως στερεάς κατάστασης πολυμερικά συστήματα λέιζερ κατανεμημένης ανάδρασης που βασίζονται στα υπό έρευνα υλικά και τα οποία διαθέτουν μονοδιάστατες και δισδιάστατες φωτονικές κοιλότητες. Τα χαρακτηριστικά εκπομπής και λειτουργίας τους περιγράφονται λεπτομερώς, μαζί με τα αποτελέσματα από πρόσθετες μετρήσεις που διερευνούν την επίδραση των μικροδομών των φραγμάτων περίθλασης στην εκπομπή φωτός του πολυμερούς. Το μήκος κύματος λειτουργίας των λέιζερ συντονίζεται συστηματικά σε πολύ μεγάλες φασματικές περιοχές μέσω ρύθμισης των υποστηριζόμενων συχνοτήτων συντονισμού των κοιλοτήτων λέιζερ.
Bridging the gap: introduction of an antimicrobial peripherally inserted central catheter (PICC) in response to high PICC central line-associated bloodstream infection incidence
Authors: DeVries Michelle , Sleweon Thomas
Published: November 2021

Objective:

To reduce the incidence of central line-associated bloodstream infection (CLABSI) in peripherally inserted central catheters (PICC) through the introduction of an antimicrobial (AM) catheter as recommended in evidence-based guidelines and standards.

Design:

Quality improvement project comparing incidence of infections pre-implementation and postimplementation of the new catheter.

Setting:

A 582-bed community teaching hospital in Northwest Indiana.

Methods:

Pre-implementation analysis of surveillance data indicated that 50% of CLABSIs occurred inpatients with PICCs in situ. A gap analysis was performed to review institutional practices against evidence-based recommendations. The use of an AM catheter was supported in each of the documents consulted. After introduction of the new device, performance was measured in a prospective manner using standardized Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) surveillance protocols for CLABSI and internal data sources for other measures.

Results:

After 30 months of data collection, the PICC CLABSI incidence reduced from a baseline rate of 1.83/1000 PICC days to 0.162/1000 PICC days (91.15% reduction, P=0.0002).

Conclusion:

Combined with continued compliance with basic prevention strategies (ie use of a central line insertion checklist/insertion bundle) and optimization of device selection and lumen justification, the introduction of an antimicrobial/antithrombogenic (AM/AT) PICC was associated with a significant reduction in CLABSI.
The effect of cemented acetabular component geometry on the risk of revision for instability or loosening
Authors: Divecha Hiren M. , O'Neill Terence W. , Lunt Mark , Board Tim N.
Published: November 2021

Aims

To determine if primary cemented acetabular component geometry (long posterior wall (LPW), hooded, or offset reorientating) influences the risk of revision total hip arthroplasty (THA) for instability or loosening.

Methods

The National Joint Registry (NJR) dataset was analyzed for primary THAs performed between 2003 and 2017. A cohort of 224,874 cemented acetabular components were included. The effect of acetabular component geometry on the risk of revision for instability or for loosening was investigated using log-binomial regression adjusting for age, sex, American Society of Anesthesiologists grade, indication, side, institution type, operating surgeon grade, surgical approach, polyethylene crosslinking, and prosthetic head size. A competing risk survival analysis was performed with the competing risks being revision for other indications or death.

Results

The distribution of acetabular component geometries was: LPW 81.2%; hooded 18.7%; and offset reorientating 0.1%. There were 3,313 (1.5%) revision THAs performed, of which 815 (0.4%) were for instability and 838 (0.4%) were for loosening. Compared to the LPW group, the adjusted subhazard ratio of revision for instability in the hooded group was 2.31 (p < 0.001) and 4.12 (p = 0.047) in the offset reorientating group. Likewise, the subhazard ratio of revision for loosening was 2.65 (p < 0.001) in the hooded group and 13.61 (p < 0.001) in the offset reorientating group. A time-varying subhazard ratio of revision for instability (hooded vs LPW) was found, being greatest within the first three months.

Conclusion

This registry-based study confirms a significantly higher risk of revision after cemented THA for instability and for loosening when a hooded or offset reorientating acetabular component is used, compared to a LPW component. Further research is required to clarify if certain patients benefit from the use of hooded or offset reorientating components, but we recommend caution when using such components in routine clinical practice. Cite this article: Bone Joint J 2021;103-B(11):1669–1677.
[RETRACTED] Identifikasi Gerakan Tanah Longsor Dengan Pendekatan Ground Shear Strain Menggunakan Pengukuran Mikroseismik di Graha Taman Nirwana Kota Semarang
Authors: Supriyadi Supriyadi , Hidayatullah Rahmad Hafid , Aji Mahardika Prasetya , Fitrianto Taufik Nur , Kusumawardani Rini
Published: November 2021

This article was retracted due to the following reasons :

Article: Identifikasi Gerakan Tanah Longsor dengan Pendekatan Ground Shear Strain Menggunakan Pengukuran Mikroseismik di Graha Taman Nirwana Kota Semarang, Vol. 10 No.1 (2020), pp: 32-36
Author: Supriyadi, R.H, Hidayatullah, Mahardika Prasetya Aji, Taufik Nur Fitrianto, Rini Kusumawardani
This article has been retracted by Publisher with the reason of improper data and error in data processing. All authors of the paper agreed with the reason.
November 2021 Imaging Case of the Month: Let’s Not Dance the Twist
Authors:   Mayo Clinic Arizona, Scottsdale, AZ USA, Panse Prasad , Gotway Michael
Published: November 2021

No abstract available. Article truncated after the first 150 words. History of Present Illness: An 82-year-old man presented to his physician for general health maintenance as well as a complaint of persistently poor quality sleep and poor appetite with weight loss. The patient had undergone robotic-assisted radical left nephroureterectomy and cystectomy with pelvic lymph node dissection and urinary diversion for left clear cell renal cell carcinoma (staged T2a, grade 2) and transitional cell carcinoma of the bladder (carcinoma in situ at surgery), approximately 9 months earlier. The patient’s bladder malignancy was initially treated with transurethral resection, with histopathology at that procedure showing high-grade papillary urothelial malignancy with lamina propria invasion, but no muscular invasion; this procedure was followed by formal complete resection approximately 3 months later. The patient’s post-operative course was complicated by significant bleeding which required transfusion of 3 units of blood. He had undergone inferior vena caval filter placement prior to surgery when preoperative testing revealed lower extremity …
Purity of 3D polarization
Authors: Sheppard Colin J. R. , Bendandi Artemi , Le Gratiet Aymeric , Diaspro Alberto
Published: November 2021

Measures of purity for 3D partially polarized fields, and in particular, the separation into circularly and linearly polarized contributions, are reexamined, and a new degree of total linear polarization introduced. Explicit expressions for the characteristic decomposition in terms of coherency matrix elements are presented, including the special case of an intrinsic coherency matrix. Parameterization of the coherency matrix in terms of ellipticity, and the directions of the ellipse normal and major axis are investigated. Phase consistency is discussed. A comprehensive collection of results regarding intrinsic polarization properties is presented.
Approximation of mode profile dispersion in the generalized nonlinear Schrödinger equation superior to the constant overlap approach for weakly guiding fibers
Authors: Arduin Andrea , Lægsgaard Jesper
Published: November 2021

An efficient numerical approach to nonlinear propagation in waveguides based on an approximation of the overlap integrals’ frequency dependence is proposed. Two test cases are studied: a weakly guiding step-index fiber and a weakly guiding parabolic-index fiber, where the approximation is compared to the standard approach of neglecting the frequency dependence and calculating the overlaps at a center wavelength

λ
0

, and benchmarked against a Gaussian quadrature approach, whose accuracy can be increased systematically. We believe that the combined accuracy and efficiency of the proposed approximation make it superior to the other two approaches in few-mode simulations.
Observation of dynamical eigenmodes induced by the moving refractive index grating of TMI in a rod amplifier
Authors: Christensen Simon L. , Michieletto Mattia , Johansen Mette M. , Maack Martin D. , Lægsgaard Jesper
Published: November 2021

We report a novel, to the best of our knowledge, analysis of high power rod fiber amplifiers by monitoring the cross-polarization of the output. Spatially and temporally resolved imaging of co- and cross-polarizations at high power amplification reveals dynamic eigenmode behavior of the rod fiber. The dynamic of the eigenmodes is caused by the moving refractive index grating written by the modal interference pattern of transverse mode instability and is the first direct observation of this refractive index grating, to our knowledge.
UV resin compound optical film by curing with the help of mold
Authors: Huang Bing-Le , Lin Zhi-Xian , Guo Tai-Liang
Published: November 2021

The preparing method of UV resin compound optical film (COF) by curing under the help of mold has been first proposed in the paper. The simulation results indicate that the theoretical values of the full width at half maximum (FWHM) for the horizontal and vertical direction are 14 degrees and 24 degrees, respectively. Then, the collimated ultraviolet light has been used to prepare the UV resin COF sample with the help of the mold. The experiment results claim the FWHMs of the horizontal and vertical direction for the sample are 16 degrees and 25 degrees when the uniformity is 86%, and it is consistent with the simulation results. The performance parameters in the BLM with COF fabricated are greater than those in the traditional one. Therefore, the COF can provide a collimated uniform plane light source and the new fabrication method is effective.
The cost-effectiveness of physician assistants/associates: A systematic review of international evidence
Authors: van den Brink G. T. W. J. , Hooker R. S. , Van Vught A. J. , Vermeulen H. , Laurant M. G. H.
Published: November 2021

Background

The global utilization of the physician assistant/associate (PA) is growing. Their increasing presence is in response to the rising demands of demographic changes, new developments in healthcare, and physician shortages. While PAs are present on four continents, the evidence of whether their employment contributes to more efficient healthcare has not been assessed in the aggregate. We undertook a systematic review of the literature on PA cost-effectiveness as compared to physicians. Cost-effectiveness was operationalized as quality, accessibility, and the cost of care.

Methods and findings

Literature to June 2021 was searched across five biomedical databases and filtered for eligibility. Publications that met the inclusion criteria were categorized by date, country, design, and results by three researchers independently. All studies were screened with theRisk of Bias in Non-randomised Studies—of Interventions(ROBIN-I) tool. The literature search produced 4,855 titles, and after applying criteria, 39 studies met inclusion (34 North America, 4 Europe, 1 Africa). Ten studies had a prospective design, and 29 were retrospective. Four studies were assessed as biased in results reporting. While most studies included a small number of PAs, five studies were national in origin and assessed the employment of a few hundred PAs and their care of thousands of patients. In 34 studies, the PA was employed as a substitute for traditional physician services, and in five studies, the PA was employed in a complementary role. The quality of care delivered by a PA was comparable to a physician’s care in 15 studies, and in 18 studies, the quality of care exceeded that of a physician. In total, 29 studies showed that both labor and resource costs were lower when the PA delivered the care than when the physician delivered the care.

Conclusions

Most of the studies were of good methodological quality, and the results point in the same direction; PAs delivered the same or better care outcomes as physicians with the same or less cost of care. Sometimes this efficiency was due to their reduced labor cost and sometimes because they were more effective as producers of care and activity.
Human-modified landscapes provide key foraging areas for a threatened flying mammal: The grey-headed flying-fox
Authors: Yabsley Samantha H. , Meade Jessica , Martin John M. , Welbergen Justin A.
Published: November 2021

Urban expansion is a major threat to natural ecosystems but also creates novel opportunities that adaptable species can exploit. The grey-headed flying-fox (Pteropus poliocephalus) is a threatened, highly mobile species of bat that is increasingly found in human-dominated landscapes, leading to many management and conservation challenges. Flying-fox urbanisation is thought to be a result of diminishing natural foraging habitat or increasing urban food resources, or both. However, little is known about landscape utilisation of flying-foxes in human-modified areas, and how this may differ in natural areas. Here we examine positional data from 98 satellite-tracked P. poliocephalus for up to 5 years in urban and non-urban environments, in relation to vegetation data and published indices of foraging habitat quality. Our findings indicate that human-modified foraging landscapes sustain a large proportion of the P. poliocephalus population year-round. When individuals roosted in non-urban and minor-urban areas, they relied primarily on wet and dry sclerophyll forest, forested wetlands, and rainforest for foraging, and preferentially visited foraging habitat designated as high-quality. However, our results highlight the importance of human-modified foraging habitats throughout the species’ range, and particularly for individuals that roosted in major-urban environments. The exact plant species that exist in human-modified habitats are largely undocumented; however, where this information was available, foraging by P. poliocephalus was associated with different dominant plant species depending on whether individuals roosted in ‘urban’ or ‘non-urban’ areas. Overall, our results demonstrate clear differences in urban- and non-urban landscape utilisation by foraging P. poliocephalus. However, further research is needed to understand the exact foraging resources used, particularly in human-modified habitats, and hence what attracts flying-foxes to urban areas. Such information could be used to modify the urban foraging landscape, to assist long-term habitat management programs aimed at minimising human-wildlife conflict and maximising resource availability within and outside of urban environments.
Art, Capitalism, and Its Discontents
Authors: Essig Linda
Published: November 2021

This essay examines how aesthetic and cultural value are transmitted from the artist directly to the audience who co-create the work’s meaning through their experience of it. While intermediaries can, do, and often should, exist, artists who maintain control of the production and distribution of their work can transcend the industrial commodification of their creative output. Ultimately, the essay argues that arts entrepreneurship is an action that does not necessarily rely on the capitalist economic system as it has developed since the time of Adam Smith, a system that classically, although not historically, relies on the separation of capital from labor.
FROM BENEDITO'S RED TO SEBASTIÃO'S BLUE: making festival and attractiveness of Marujada in the Brazilian Amazon
Authors: Canal Maria Augusta Freitas Costa , Palheta Hygo da Silva , Castro Milene de Cássia Santos de
Published: November 2021

The attractiveness from events based on sociocultural valorization foments the tourist destination. Thus, this work seeks to analyze the act of making festivals and the attractiveness of Marujada in the Brazilian Amazon in Tracuateua city. The analysis procedures involved the research in a qualitative way, through the survey of documentary and bibliographic data, with fieldwork including semi-structured interviews and field notes with guided observation script and semi-structured interview conducted with 12 organizers and makers of Tracuateua’sMarujada festival. The results demonstrate that the act of making festivals allows the fraternization of frequenters, through the act of partying, and the attractiveness provided by Marujada can attract tourist flows. In addition to encouraging the culture of the microregion of Bragança and strengthening the festival. It is considered that the Marujada party contributes positively to the safeguard of local culture.
Narrativas, Influências e Experiências: uma breve análise das reflexões de Pierre Bourdieu / Narratives, Influences and Experiences: a brief analysis of Pierre Bourdieu's reflections
Authors: Caffé Filho Hesler Piedade , Vieira Denes Dantas , Oliveira Lucia Marisy Souza Ribeiro de , Beserra Elijalma Augusto , Silva Abimailde Maria Cavalcanti Fonseca da
Published: November 2021

Resumo: Esse artigo traz reflexões sobre como a tríade (habitus, campo e capital) de Bourdieu pode explicar o conjunto de parâmetros que norteiam o comportamento das pessoas. Percorre ainda a ideia de que as influencias, narrativas e alienações são geradas a partir de conhecimentos tradicionais e científicos e de interpretação de quem lê e se apropria dessas narrativas, e que pode dar início (ou continuidade) a uma crise cultural ou de autonomia nos sujeitos de uma maneira geral. Encerra falando de alienação e limites que são gerados a partir desses fatores, sugerindo que o mundo ideal é aquele onde as pessoas possam ser autônomas no seu pensamento, agir preservando o equilíbrio dos sujeitos e que a linguagem livre seja o vetor dessa troca de vivências.
Pobreza, Educação e os Direitos Humanos Dentro da Sociedade / Poverty, Education and Human Rights Within Society
Authors: Alberti Andressa , Silva Bruna Becker da , Souza Renan , Zanoni Eliton Marcio , Alberti Adriano
Published: November 2021

Resumo: A sociedade em meio aos seus vários aspectos norteadores da formação do ser humano, busca responder por meio de vários estudos como melhorar o desenvolvimento do meio social e da vivencia entre os seres humanos. A pobreza não é falta de cultura ou falta de educação, muito menos a falta de bens materiais como muitas pessoas pensam, pois a compreensão dela é muito mais complexa do que isso e é de suma importância a compreensão sobre isso. O presente artigo presente artigo, por meio de uma revisão da literatura, pontua sobre pobreza, educação e os direitos humanos dentro da sociedade. Palavras Chave: Ser Humano, Sociedade, compreensão. Abstract: Society, in the midst of its various aspects that guide the formation of human beings, seeks to respond through various studies on how to improve the development of the social environment and experiences among human beings. Poverty is not lack of culture or lack of education, much less the lack of material goods as many people think, because understanding it is much more complex than that and understanding about it is of paramount importance. The present article in this article, through a literature review, points out about poverty, education and human rights within society. Keywords: Human Being, Society, Understanding.
Carotid stiffening predicts cardiovascular risk stratification in mid-life: non-invasive quantification with ultrafast ultrasound imaging
Authors: Zhu Zhengqiu , Chen Lingshan , Liu Wenjun , Wu Yiyun , Zou Chong , Zhang Xinyi , He Shanshan , Wang Yinping , Shen Bixiao , Ma Xuehui , Gao Hui , Luan Yun , Huang Hui
Published: November 2021

Purpose: The present study investigated the association between Systematic COronary Risk Evaluation (SCORE)-estimated cardiovascular risk and carotid stiffening in a middle-aged population using ultrafast pulse wave velocity (ufPWV).Methods: This study enrolled 683 participants without known cardiovascular disease or diabetes mellitus who underwent ufPWV measurements. Clinical interviews, physical examinations, laboratory findings, carotid intima-media thickness (cIMT), pulse wave velocity (PWV) at the beginning of systole (PWV-BS), and PWV at the end of systole (PWV-ES) were assessed. Each participant underwent an assessment of SCORE risk based on major cardiovascular risk factors (CVRFs), including age, sex, smoking, systolic blood pressure (SBP), and total cholesterol (TC). Crude and adjusted odds ratios (ORs) with 95% confidence intervals and ordinal logistic regression were used. Overall CVRFs were adjusted to assess ORs.Results: cIMT and carotid stiffening in PWV-BS and PWV-ES were significantly different between sex subgroups (all P<0.05), but only PWV-ES increased gradually in age and SCORE-estimated risk subgroups (all P<0.05). Compared with cIMT (r=0.388, P<0.001) and PWV-BS (r=0.159, P<0.001), PWV-ES was more strongly correlated with SCORE categories (r=0.405, P<0.001). Higher PWV-ES values were associated with SCORE categories independently of sex, SBP, TC, and smoking in moderate-risk and high-risk subgroups (OR, 1.63; P<0.001 and OR, 2.12; P=0.024, respectively), but were not independent of age in all risk subgroups (all P>0.05).Conclusion: Carotid stiffening quantified by ufPWV is linked to SCORE categories, and elevated PWV-ES may aid in cardiovascular risk stratification.
Governamentalidades e depurações hierárquicas dos direitos humanos no Brasil: A educação pública e a população LGBT+.
Authors: Marco Aurelio Maximo Prado  , João Gabriel Maracci  , Igor Ramon Lopes Monteiro
Published: November 2021

O presente artigo visa analisar as relações entre governo, educação e políticas para a diversidade sexual e de gênero no contexto das últimas duas décadas no Brasil. Para tanto, propusemos uma divisão em três lógicas que definem formas articuladas de atores políticos heterogêneos na redefinição de políticas educacionais para a diversidade sexual e de gênero. Considerando tais lógicas, perspectivamos as ações estatais no campo educacional voltadas para a população LGBT+ em três diferentes modos de governabilidade: a adesão com baixa institucionalidade; o rechaço sustentado pela emergência das ofensivas antigênero e, por fim, a assimilação e cooptação da diversidade no interior do Executivo Federal. Tais formas de governabilidade nos permitem analisar eventos recentes a partir de sua historicidade, evidenciando não apenas as rupturas, mas também as continuidades nas gestões governamentais. Deste modo, argumentamos que o contexto de baixa institucionalização das políticas da primeira lógica, somado ao contexto de emergência de ofensivas antigenero e da sua legitimação através de sua operacionalização no estado, contribuíram para o presente cenário de ressignificação dos direitos humanos e legitimação institucional da heterossexualidade e da cisgeneridade como normas obrigatórias e naturalizante.
Obstáculos para la inclusión de estudiantes disidentes sexuales y de género en escuelas confesionales chilenas
Authors: Espejo Juan Cornejo
Published: November 2021

El artículo tiene como propósito analizar los procesos de integración de estudiantes disidentes sexuales y de género en establecimientos educacionales confesionales de distinta dependencia administrativa de cinco regiones de la zona centro - sur de Chile. Desde el punto de vista metodológico la investigación adscribe a un enfoque cualitativo, basado en un estudio descriptivo – interpretativo llevado a cabo a través de entrevistas semiestructuradas aplicadas a distintos agentes educativos de 12 establecimientos durante el año 2019. Entre los principales hallazgos destaca la tensión que implica la presencia de disidentes, cuya integración fluctúa entre el silenciamiento y el negacionismo dependiendo de la orientación religiosa del establecimiento. En ese contexto, los establecimientos católicos tienden a acoger a los disidentes en cuanto permanezcan en el closet, aquellos que se resisten se transforman en “estudiantes problema”. Las escuelas evangélicas, se caracterizan por su intransigencia, con sermones reiterativos acerca de lo abominable que resulta una orientación y/o identidad disidente. Los establecimientos adventistas, aun cuando no tan frontales, se muestran muy activos en sus programas de adoctrinamiento religioso cuyo propósito es desincentivar cualquier posible disidencia. El establecimiento mormón, por su parte, tiende a evadir el tema, negándose a la posibilidad de que entre su estudiantado pueda haber disidentes.
COVID-19 impact on e.commerce usage
Authors: Usas Antanas , Jasinskas Edmundas , Zagurska-Antoniuk Viktoriia , Savitskyi Vladyslav , Fuhelo Pavlina
Published: November 2021

Online stores, ad portals, shopping apps have become part of everyday life in 2020-2021. The Covid-19 epidemic has rapidly forced numerous entities (public, business, and private) to become predominantly oriented to electronic commerce in the last few months (Pejić-Bach, 2021). Business in the online space faces new challenges that require additional knowledge and skills.  The object of the research is the assessment how covid-19 impact on ecommerce usage in Lithuania. The aim of the work is to examine ecommerce usage in Lithuania during covid-19 pandemic. Methods: scientific literature analysis, statistical data analysis.  Businesses had to offer a wider range of services in order to survive. The issue of cybersecurity has grown. Consumers have also reacted ambiguously to this situation. Not only are economic factors that determine the frequency or quantity of consumer purchases distinguished, but also social and psychological factors, such as loss of motivation or apathy. The vast majority of Lithuanian shoppers were selling local online shops. The amount of money spent on online shopping has also increased. The pandemic has increased the scope of ecommerce and the range of services in Lithuania despite the deteriorating economic and social situation.
Using Random Forest Regression to Determine Influential Force-Time Metrics for Countermovement Jump Height: A Technical Report
Authors: Merrigan Justin J. , Stone Jason D. , Wagle John P. , Hornsby W. G. , Ramadan Jad , Joseph Michael , Galster Scott M. , Hagen Joshua A.
Published: November 2021

Merrigan, JJ, Stone, JD, Wagle, JP, Hornsby, WG, Ramadan, J, Joseph, M, and Hagen, JA. Using random forest regression to determine influential force-time metrics for countermovement jump height: a technical report. J Strength Cond Res 36(1): 277–283, 2022—The purpose of this study was to indicate the most influential force-time metrics on countermovement jump (CMJ) height using multiple statistical procedures. Eighty-two National Collegiate Athletic Association Division I American football players performed 2 maximal-effort, no arm-swing, CMJs on force plates. The average absolute and relative (i.e., power/body mass) metrics were included as predictor variables, whereas jump height was the dependent variable within regression models (p < 0.05). Best subsets regression (8 metrics, R
2 = 0.95) included less metrics compared with stepwise regression (18 metrics, R
2 = 0.96), while explaining similar overall variance in jump height (p = 0.083). Random forest regression (RFR) models included 8 metrics, explained ∼93% of jump height variance, and were not significantly different than best subsets regression models (p > 0.05). Players achieved higher CMJs by attaining a deeper, faster, and more forceful countermovement with lower eccentric-to-concentric force ratios. An additional RFR was conducted on metrics scaled to body mass and revealed relative mean and peak concentric power to be the most influential. For exploratory purposes, additional RFR were run for each positional group and suggested that the most influential variables may differ across positions. Thus, developing power output capabilities and providing coaching to improve technique during the countermovement may maximize jump height capabilities. Scientists and practitioners may use best subsets or RFR analyses to help identify which force-time metrics are of interest to reduce the selectable number of multicollinear force-time metrics to monitor. These results may inform their training programs to maximize individual performance capabilities.
Cyberbodies
Authors: Asadi Torang X.
Published: November 2021

In addition to its metaphorical and practical influences, the internet has informed New Agers’ cosmologies and corresponding bodily practices by requiring a rethinking of the physical universe in the face of virtual ubiquity. It has allowed them to imagine new ways of making space in their ontological realities for metaphysical, energetic substances. We can see, perhaps somewhat counterintuitively, that the digital has made the spiritual ever more material and situated in the flesh for New Agers searching for the true nature of existence. Drawing from ethnographic fieldwork from 2016 to 2018 and ongoing research with energy healers in the San Francisco Bay Area, this “anthropology of virtual matter”—understanding how the virtual has caused a paradigm shift in how we think about the material world—gives us fresh eyes with which to see the New Age. It even forces us to reconsider spiritualities as material ontologies, the conception of materiality that shapes how believers understand and interact with the world around them through their bodies, sensoria, and metaphysical appendages.
QuiltSpeak
Authors: Bell-Kite Diana
Published: November 2021

The exhibit QuiltSpeak: Uncovering Women’s Voices Through Quilts provides a model for using material culture research to unearth the experiences of marginalized historical actors. Each of the forty quilts from the North Carolina Museum of History’s permanent collection displayed in QuiltSpeak—made by a racially and economically diverse selection of quilters from the past two hundred years—served as a portal into a woman’s life and a representation of her self-expression. Interactive elements empowered visitors to decode material culture themselves and connect their own experiences to the quiltmakers’. This article examines the exhibit’s conceptualization, development, and outcomes with the contention that heretofore unheard voices can often be discovered right under our proverbial noses.
Model and method for representing complex dynamic information objects based on LMS-trees in NoSQL databases
Authors: Maksymov Oleksandr S. , Malakhov Eugene V. , Mezhuyev Vitaliy I.
Published: November 2021

The article analyzes the existing approaches to the description of large dynamic information objects in the construction of Automated control systems. Introduced and defined the concept of a ComplexDynamical Information Object. A comparative analysis of the temporal complexities of tree-like structures is carried out and the optimal one for working with ComplexDynamical Information Objectis selected. Most modern automated control systems use various approaches to describe automation objects for their operation. Under the automation object, we mean functional objects that are described in the form of structural models that reflect the properties of physical objects. Thus, for optimal work with complex dynamic information objects, we have developed our own model and method for describing the LMS-tree (Log-structured merge-tree), with the ability to split and store down to elementary levels. One of the features of our approach to describing objects is the presence of tree-like levels -the so-called “leaves”, by which we mean special tree elements that expand the description of the tree structure of a particular tree level. The minimal elements of the leaves of the tree –“veins”-are details, that is, elementary information elements. A leaf is a combination of “veins”(details) according to certain characteristics, which provide extended information about the level of the tree object. An atomic-level descriptor is a multiple NoSQL database field (array) where the tree level number is the index of the database array. This approach allows you to retrieve and group objects according to the element level of the tree definition.
Summary of Task Force Team Work to Come up with Certificate System of Pancreatobiliary Endoscopist
Authors: Park Chang-Hwan
Published: November 2021

It has been appealed to come up with the certificate system of pancreatobiliary endoscopist from summer endoscopic retrograde cholangiopancreatography camp in 2018. All members of Policy-Quality Management Board, Educational Board, and Insurance Affaires Board had the first workshop preparing for the certificate system of pancreatobiliary endoscopist on December 8, 2018. They discussed prerequisites to the certificate system of pancreatobiliary endoscopist as well as pros and cons on the system. After trying to prepare it over half year, a task force team (TFT) set sail for the certificate system of pancreatobiliary endoscopist. Throughout one workshop and five conferences, the TFT confirmed the official name of certificate system of pancreatobiliary endoscopist and made rules and regulations on the qualification of guidance medical specialists, training hospital qualifications, acquisition, maintenance and repair of certificate, and eligibility criteria for renewal.
Endoscopic Ultrasound Guided Fine Needle Aspiration and Biopsy for Pancreatic Disease
Authors: Lee Kwang Hyuck
Published: November 2021

The endoscopic ultrasound (EUS) is a device with an ultrasound probe on the tip of endoscope. We can observe the surrounding structures outside the alimentary tract by using EUS. It is also possible to get a tissue from the pancreatic lesion for histopathologic diagnosis by using EUS. The development of devices and techniques of EUS guided tissue acquisitions made it the choice of non-operative pathologic test for pancreatic diseases. This paper describes the clinical applications of this procedure in pancreatic lesions from the recent European and Korean guidelines, including how to choose the needle, role of rapid on site evaluation, usage of stylet, suction and fanning technique, how to process acquired specimen, procedure-related complications and educations of this method.
Relationships between Subclinical Hypothyroidism and Metabolic Syndrome and Vitamin D Status in Korean Adults: Korea National Health and Nutrition Examination Survey 2013-2015
Authors: Kim You-Lee , Han A-Lum , Shin Sae-Ron
Published: November 2021

Background: Many studies have established the association between overt hypothyroidism and metabolic syndrome (MS). However, the relationship between subclinical hypothyroidism (SCH) and MS varies from study to study. This study aimed to investigate associations between SCH and components of MS and vitamin D status in Korean adults.Methods: Using data from the 6th Korea National Health and Nutrition Examination Survey (2013-2015), chi-squared tests and t-tests were used to explore relationships between thyroid hormones and components of MS and vitamin D status. Multiple regression analysis was undertaken to assess relationships between SCH and components of MS and vitamin D.Results: Systolic blood pressure and fasting glucose were significantly higher in the euthyroid (EUT) group than in the SCH group, and vitamin D status was significantly lower in the SCH group than EUT. However, in multiple regression analysis, SCH presented no significant association with components of MS or vitamin D status even after adjusting for age, sex, drinking, and smoking.Conclusions: In Korean adults, there is no significant association between SCH and MS or vitamin D.
Fast Food Intake Frequency and Health Practices
Authors: Hong Seung-Hee
Published: November 2021

Background: The purpose of this study was to examine the effect of fast food awareness, dietary behaviors, and health practices according to the fast food intake frequency in Korean adults.Methods: The investigation was conducted using a self-completed questionnaire for adults. Chi-square test, correlation analysis, and multiple regression analysis were performed to evaluate the association between intake frequency of fast food and related factors.Results: The frequent intake group’s (more than twice a week) results were 38.6%, the normal intake group (less than twice a week) was 33.3%, and the non-intake group (less than once a month) was 28.1%. Subjects who frequently consumed fast food were positively aware of their fast food consumption. The frequent intake group showed significantly higher body weight gain after fast food intake than other groups. They consumed more foods containing oil and wheat flour than the non-intake group whose intake was mainly protein-sourced foods, green vegetables, and fruits, and dietary behavior showed statistically significant differences according to intake frequency of fast food. The fast food non-intake group was significantly better at practicing health practices such as maintaining health and normal weight, regular exercise, and correct posture than other groups. It was seen that the higher frequency of fast food intake group appeared to follow fewer health practices than other groups.Conclusions: High frequency of fast food intake is associated with undesirable dietary behaviors such as high caloric intake and low health practices, suggesting the need for appropriate information to reduce the nutritional imbalance caused by fast food intake.
Impact of Surface and Deep Acting Emotional Labor on Emotional Dissonance among Ambulatory Care Nurses
Authors: Kang Tae Rim , Park Jeong Yun
Published: November 2021

Background: Ambulatory care represents the first point of contact between the patient and the hospital.Kindness is strongly emphasized for ambulatory care nurses in customer-centered medical services. The purpose of this study was to investigate the relationship among surface acting, deep acting, and emotional dissonance of emotional labor and to identify the influencing factors on emotional dissonance of ambulatory care nurses in a tertiary hospital.Methods: This study is a correlational study. The data was collected using emotional labor scales from 163 nurses in March 2017.Results: The surface acting, deep acting of emotional labor, and emotional dissonance were 3.71±0.69, 3.76±0.57, and 3.36±0.90 respectively in the ambulatory care nurses. The result of the multiple regressions indicates that surface (β=0.77,P<0.001) and deep acting (β=0.12, P=0.009) of emotional labor predict 67.6% (F=188.99,P<0.001) in emotional dissonance of ambulatory care nurses.Conclusions: To improve emotional dissonance for ambulatory care nurses, it is necessary to develop and utilize emotional labor management program and effective emotional labor management.
The Association between Depressive Mood and Conventional and Electronic Cigarette Dual Use in Adult Male: Using Korea National Health and Nutrition Examination Survey
Authors: Lee Jun Hyung , Lee Eon Sook
Published: November 2021

Background: Depression is well known to be associated with nicotine dependence. Recent studies reported higher depressive score is associated with use of e-cigarettes, however, little study showed the association between depression and both cigarette dual use. The purpose of this study is to evaluate the association between depressive mood and conventional and electronic cigarette dual use among male adults.Methods: Data of 7,459 male adults from sixth and seventh Korea National Health and Nutrition Examination Survey (2014, 2016, and 2018) were analyzed. Patient Health Questionnaire-9 (PHQ-9), current smoking status, and electronic cigarette use status were evaluated among them. The association between depressive mood and electronic cigarette use were assessed after adjusting age, education, income, alcohol, and perceived stress level using multivariate logistic regression analysis. The risk of depressive mood for dual users were also assessed. STATA 11.0 (Stata Corp., College Station, TX, USA) were used.Results: The both group of e-cigarette current user or ex-user reported higher depressive scores (PHQ-9) than never-user group (never-user group 1.94±0.05, ex-user group 2.57±0.13, current user group 2.69±0.22, P<0.001). In the multivariate logistic analysis, 1 point increase of depressive mood score was associated with risk of e-cigarette current use (odds ratio [OR], 1.062; 95% confidence interval [CI], 1.021-1.105) among total male adult group or conventional & electronic tobacco dual use (OR, 1.054; 95% CI, 1.012-1.098) among current smokers.Conclusions: Depressive scores were positively associated with e-cigarette use or both conventional or e-cigarette use. It is necessary to evaluate and treat smoker’s depressive mood for tobacco control.