bluuebunny/crossref_metadata_2025 huggingface dataset:
Perception, Motivation et Acceptation des Acteurs de l’Unite de Formation et de Recherche des Sciences Medicales d’Abidjan (Ufrsma) Face a l’Integration de la Formation a Distance (FAD)
Authors: Alice Dosso Binaté Namodé , Ake Sassor Odile Purifine
Published: December 2022

Le passage vers la formation bimodale est de plus en plus répandu au sein des universités dites « campus » afin de rendre plus accessible la formation au niveau de l’enseignement supérieur. Cependant cette transition nécessite la prise en compte des perceptions, motivation et acceptation des acteurs de l’institution, censés être sujets et bénéficiaires du projet. L’UFHB est confrontée à de nombreux défis telle que la massification des apprenants, qui l’empêche d’atteindre pleinement ses objectifs. En tant qu’université pilote de l’AUF (Agence Universitaire de la Francophonie) concernant l’introduction de la FAD en Côte d’Ivoire, afin de faire face à cette situation, elle a décidé d’introduire la FAD au sein de ces différentes UFR dont l’UFRSMA. Mais est-ce que les acteurs de cette institution sont préparés, disposés et outillés pour réussir ce changement ? Il s’agit d’une étude qualitative dont l’enquête a été réalisée du 16 décembre 2019 au 08 janvier 2020 à l’UFR des Sciences Médicales d’Abidjan. Ont été inclus dans l’étude trois administrateurs de l’UFHB, quatre enseignants et trente étudiants de l’UFRSMA. Les données ont été recueillies lors d’entrevues individuelles et de focus group à l’aide de guides d’entrevue. L’objectif de cette étude qualitative est de recueillir les informations sur la motivation et l’acceptation des acteurs (enseignants et étudiants) par rapport à l’introduction de la formation à distance à l’UFR des sciences médicales d’Abidjan. Le postulat de départ stipule que lorsque la perception est positive, les personnes sont plus motivées et l’acceptation est garantie. L’outillage méthodologique utilisé a permis de ressortir les perceptions mitigées des acteurs autour de ce changement pédagogique. Le renforcement de capacités des enseignants en technologie éducative a été enclenché, ainsi tous les enseignants enquêtés avaient des compétences en matière de cours en ligne et étaient favorables à son introduction au sein de l’UFRSMA. Cependant ils souhaitaient que les conditions favorables soient réunies avant la mise en œuvre de la FAD. Quant aux étudiants, ils étaient aussi favorables à l’introduction de la FAD bien que certains demeurent réticents. Comme les enseignants, ils ont évoqué la nécessité de réunir toutes les conditions essentielles avant le démarrage de la FAD. La théorie de la cognition sociale d’Albert Bandura est la théorie de référence. Elle permet de comprendre qu’il existe bien une relation entre la perception, la motivation et l’acceptation de l’individu face à une activité ou un projet. En d’autres termes, les acteurs éducatifs de l'UFRSMA pour accepter l'enseignement en ligne doivent être au minimum engagés, mobilisés et cette mobilisation est étroitement liée au degré de réussite potentiel qu’ils attendent.
Evolution of gold sources in the process of formation of gold deposits (evidence from Eastern Yakutia)
Authors: Kokin A. , Kravcov R.
Published: December 2022

In contrast to the established ideas about the relationship of gold mineralization with any specific source, a model is proposed for the evolution of different sources during the formation of geological structures in the eastern framing of the Siberian Platform. The model is based on the calculation of regional clarkes of sedimentary, igneous rocks and minerals with the allocation of stratigraphic levels of primary gold enrichment in sedimentary rocks. The poly-stage and multi-stage nature of the evolution of sources is established through the redistribution of gold in the composition of sedimentary rocks and minerals under the influence of various endogenous heat and mass transfer agents, in particular, under the influence of carbonatites. The main condition for the localization of gold mineralization in the region is the presence of levels of primary supraclarke gold concentrations in turbidites R3, C3—P1, T3 of the deltaic facies of submarine slopes. The main gold concentrators in sediments are marcasite and pyrite. Under the influence of various heat and mass transfer agents, gold is redistributed along the heat flow front, forming zones of dispersed mineralization with its high contents in pyrite and arsenopyrite. Then, under the conditions of late superimposed hydrothermal-metasomatic processes, gold-bearing pyrites and arsenopyrites are released from most of the gold, which appears in the composition of ores of the late stage of ore formation in the form of visible gold particles.
Pengembangan Lembar Kerja Peserta Didik Menulis Permulaan Berdasarkan Kurikulum 2013 Tema 5 Subtema 1 Kelas II SDN Slawu II Jember
Authors: Nurriyah Alifin , Suhartiningsih Suhartiningsih , Kurniasih Fitria
Published: December 2022

Pengembangan lembar kerja peserta didik (LKPD) menulis permulaan bertujuan sebagai sarana menguasai kecakapan menulis bagi siswa kelas rendah yang dimaksudkan menjadi bekal siswa dalam menyalin, mencatat, dan menyelesaikan tugas sekolah. Pengembangan LKPD difokuskan pada latihan menulis permulaan berupa menyusun huruf menjadi sebuah kata, mengidentifikasi suku kata, melengkapi kalimat rumpang, menulis kalimat menggunakan bahasa sendiri serta menuliskan pengalaman dengan kalimat sendiri yang diintegrasikan dalam pembelajaran tema 5 subtema 1 kelas 2 SD. Penelitian ini mengacu pada metode pengembangan Research and Development (R&D) menurut Sugiyono (2018:409) yaitu: (1) potensi masalah (2) pengumpulan data, (3) desain produk (4) validasi desain, (5) revisi desain, (6) uji coba produk, (7) revisi produk, (8) uji coba pemakaian, (9) revisi produk akhir, dan (10) implementasi dan diseminasi. Data penelitian diambil melalui wawancara guru kelas SDN Slawu 02 dan SDN Jumerto 1 Jember, angket respon siswa dan post-test hasil belajar. Hasil penelitian ini mendapatkan hasil positif dari respon siswa pada tahap ujicoba produk sebesar 92.59 % dan pada tahap ujicoba pemakaian mendapatkan skor 95.75% serta hasil post-test mendapatkan skor 85.83. Berdasarkan pemaparan tersebut, LKPD Menulis Permulaan sangat layak digunakan dalam proses pembelajaran serta memberikan pengaruh yang baik terhadap hasil belajar siswa.
Korelasi Kecerdasan Emosional terhadap Kemampuan Bersosialisasi Siswa Kelas VI SDN Kemuning Sidoarjo
Authors: Tamarradini Fikria Hannum , Fitriyah Chumi Zahroul , Kurniasih Fitria
Published: December 2022

Penelitian ini bertujuan untuk mengetahui korelasi yang signifikan antara kecerdasan emosional dengan kemampuan bersosialisasi yang dimiliki siswa  kelas VI SDN Kemuning Sidoarjo. Subyek penelitian sebanyak 58 siswa berdasarkan sampel populasi. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian korelasional dengan pendekatan kuantitatif. Metode penelitian yang digunakan adalah wawancara, observasi, dokumentasi, dan angket. Instrumen yang digunakan dalam penelitian ini berupa angket kecerdasan emosional dan kemampuan bersosialisasi siswa. Data dianalisis dengan menggunakan korelasi Product Moment Pearson. Hasil penelitian menunjukkan hubungan antara kecerdasan emosional dengan kemampuan bersosialisasi siswa sebesar 0,596. Interpretasi koefisien korelasi tersebut berada di kategori sedang, dan kedua variabel terbukti memiliki hubungan yang positif dan signifikan. Berdasarkan taraf signifikansi 0,05 atau taraf kepercayaan 95% untuk N=58 sebesar 0,259 sedangkan hasil koefisien korelasi (rhitung) sebesar 0,596. Hal ini menunjukkan bahwa Ho ditolak dan H1 diterima sebab rhitung lebih besar dari rtabel (0,596 > 0,259). Demikian bisa dikatakan bahwa semakin baik kecerdasan emosional siswa maka semakin baik pula kemampuan dalam bersosialisasinya.
A Coulomb-féle súrlódással csillapított rezgőmozgás – oktatói szemmel
Authors: Barta Edit
Published: December 2022

A hallgató a tanulmányai során gyakran szembesül azzal, hogy egyes téma tárgyalásmódját „nem érti”, nehezen sajátítja el. Emögött gyakran az áll, hogy hiányosak a megértéshez szükséges matematikai és fizikai előismeretetek. A súrlódással csillapított harmonikus rezgőmozgás egy szép példája annak, hogyan építhető fel egy új anyagrész úgy, hogy az minden ponton kapcsolódjék a hallgatók feltételezett előismereteihez.
Debt and Economic Growth: The Case of Indonesia
Authors: Sari Vita Kartika
Published: December 2022

Debt is an intriguing state financing to be studied and analyzed because debt can have positive or negative impacts. Sources of debt can be from the issuance of domestically-sold bonds or foreign investment. Indonesia uses debt instruments to address the fiscal gap and increase capital for economic development. This study aims to analyze the impact of debt on Indonesia’s economic growth and investment during the 1970-2018 period, using the Autoregressive Distributed Lag (ARDL) method. The study found that debt had a negative effect on GDP in the short and long run. Meanwhile, it did not affect investment in the short run but had a negative effect in the long run. The study model also had good stability as a result of Cusum and Cusum of Squares testing. Thus, appropriate debt management policies are needed to support economic growth.
Does Switching Cost Affect Dual Rural Banks Market Power?
Authors: Fajri Moh Najikhul , Purwono Rudi
Published: December 2022

This study aims to review the effect of switching costs on rural bank market power. This study is using dynamic panel regression of the Generalized Method of Moments (GMM). This paper used panels of 1266 rural banks and 113 Sharia Rural banks from 2013 to 2019. To further analyze this study using Lerner Index as proxies of market power, Bertrand Competitions models as proxies of switching costs, and banking indicators covering bank size, equity, non-interest income, and the burden of allowance for productive assets (Lost Loans Provision). The results show that switching costs have a significant positive effect on the conventional rural bank and negatively affect sharia rural bank's market power. This condition is caused by various reasons, namely the limited choice of rural banks so that consumers survive the switching costs charged. Meanwhile, in sharia rural bank transparency is clearly seen on the side of mudharobah and musyarakah which makes it unable to increase financing margins freely.
The Demand Creation Effect on the Indonesian Manufacturing Industry
Authors: Sulistyaningsih Lusi , Machmud T.M. Zakir S.
Published: December 2022

This study analyzes the impact of Foreign Direct Investment that creates a demand creation effect on domestic companies in the Indonesian manufacturing industry in 2010-2015. This study uses Input and Output data for 2010 and Industri Besar Sedang data in 2010-2015, both of which come from the Badan Pusat Statistik. The Fixed Effects model came out as the best model because it reflected different firm characteristics. The study concludes that the larger the foreign presence and the firm’s size in an industry, the more demand-creating effect it will create. However, FDI enters highly concentrated industries and industries with high levels of imports, which will negatively affect the demand creation effect.
CELEBRITY ENDORSERS VS EXPERT ENDORSERS: WHO CAN AFFECT CONSUMER PURCHASE INTENTION FOR HALAL FASHION PRODUCT?
Authors: Timur Yan Putra , Ratnasari Ririn Tri , Author Nailul
Published: December 2022

This study aims to analyze the effect of using two types of endorsers, namely celebrities and expert endorsers, on consumer purchase intentions between halal fashion products. The method used in this study is PLS-SEM for model evaluation. This study analyzes the effect of using two types of endorsers, namely celebrities and expert endorsers, on consumers' purchase intentions between halal fashion products. The method used in this study is PLS-SEM for model evaluation. This study gave respondents a full-color print advertisement containing a photo of artist April Jasmine as a celebrity endorser and expert fashion designer Hannie Hananto as an expert endorser. We use celebrity and expert endorsers as independent variables and consumer purchase intention in halal mode as the dependent variable. The result showed that celebrity endorsers positively influence consumer purchase intention in halal fashion products. Meanwhile, expert endorser does not affect consumer purchase intention on halal fashion products. The results of this study reveal that celebrity endorsers positively affect consumers' purchase intentions for halal fashion products. However, marketers must pay attention to the suitability of selecting the type and attributes of the endorser with the product they support. The goal is that the marketing costs incurred by the company in the endorser use strategy are more effective and follow marketing objectives.
Cobas® 4800 HPV test is accurate for detecting high risk Human Papillomavirus from urine samples at dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia
Authors: Wityawan Indiarto , Andrijono  , Kekalih Aria
Published: December 2022

HIGHLIGHTS
1. The presence of Human Papillomavirus (HPV) can be detected using urine samples, as compared to cervical samples, by means of Cobas® 4800 HPV test.2. The concordance between cervical and urine samples for HPV DNA was found as much as 84.72%.3. Urine samples subjected to Cobas® 4800 HPV test is helpful to treat HPV infection.
 
ABSTRACT
Objective: To find the accuracy, sensitivity, specificity, as well as predicted values, both positive and negative, of urine samples using Cobas® 4800 in detecting high risk Human Papillomavirus.
Materials and Methods: This study was a cross-sectional study with a total of 72 samples taken from medical records of hrHPV DNA examination with Cobas® 4800 in 2017-2020. Study subjects were called for re-examination of urine samples and cervical samples using Cobas® 4800. Samples with positive hrHPV DNA in the cervix, urine, or both were examined for cervical fluid-based cytology (LBC). Data were analyzed using Chi-square.
Results: Overall, 84.72% agreement was detected through specimens of urine and cervical mucus tested of hrHPV DNA with Cobas® 4800. In all samples, a significant rate of concordance detection of hrHPV DNA with Cobas® 4800 was reported (ka = 0.62; 95% IC: 39-84). In this population, in determining the presence of hrHPV DNA in cervical and urine specimens, it was found that the sensitivity, specificity, positive predictive value and negative predictive value were respectively 87.5% (95% IC: 64–97%), 84% (95% IC: 72–91%), 60.9% (95% IC: 40.8–77.8%), and 96 % (95% IC: 86.3–98.9%).
Conclusion: The presence of hrHPV infection in the cervix can be determined by detecting hrHPV DNA in the urine. According to these findings, urine samples subjected to the Cobas® 4800 HPV test may be helpful for the clinical treatment of HPV infection.
Comprehensive management of pregnant woman with Sjögren’s syndrome
Authors: Gunawan Giovanny Azalia , Ayu Dyah Rahadina Adinda , Prasetyo Budi
Published: December 2022

HIGHLIGHTS
1. Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. 2. Comprehensive management of pregnant women with Sjögren’s syndrome was described.3. Clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy are needed by women with Sjögren’s syndrome.
 
ABSTRACT
Objective: To illustrate the comprehensive management of pregnant women with Sjögren syndrome.
Case Report: A 24 years old women came to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, due to Sjögren syndrome in 35/36 weeks of gestasional age for routine examination. She was first diagnosed with Sjögren syndrome in February 2018 because she complained of dry eyes and hair fall out. This was her first pregnancy. Laboratory result showed positive ANA test. The patient had hypertension with controlled blood preasure and dry eyes. The patient was diagnosed with primigravida 35-36 weeks of pregnancy, single live intrauterine, head presentation, IUGR, screening preeclampsia was positive, and there was complication with Sjögren’s syndrome. The patient was treated by multidisciplinary team consisting of obstetricians, internists, ophthalmologists and neonatologists.
Conclusion: Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. The exact cause of Sjögren's syndrome is still not known. Women with Sjögren’s syndrome should have clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy because Sjögren syndrome was a rare case during pregnancy. Close monitoring and proper management was imperative to detect the early complication.
Dynamics and stability results for novel coronavirus (2019-nCov) model via Caputo-Fabrizio fractional derivative
Authors: Vivek D. , Elsayed Elsayed , Kanagarajan K.
Published: December 2022

Recently, many mathematical models have been studied to better understand the coronavirus infection. Most of these
models are based on classical integer-order derivatives which cannot capture the fading memory and crossover behavior found in
many biological phenomena. Therefore, the aim of this paper is to establish the existence and uniqueness of solutions to novel
coronavirus (COVID-19) model including Caputo-Fabrizio (CF)-fractional derivative. We derive existence and uniqueness results with
the help of properties of CF-fractional calculus, fixed-point theorem and iterative method. Finally, the model is proved to have a
disease-free and an endemic equilibrium point.
Generalized symmetric bi-derivations in MV-algebras
Authors: Koç Samet , Yazarlı Hasret
Published: December 2022

In this study, we define the generalized symmetric bi-derivation and its trace on MV-algebras and give its examples. We
investigate some properties of generalized symmetric bi-derivation’s trace. We introduce isotone generalized symmetric bi-derivation
and bi-additive generalized symmetric bi-derivation. We show that if A is a linearly ordered MV-algebra, Γ is a bi-additive generalized
symmetric bi-derivation on A related to symmetric bi-derivation D and γ is a trace of Γ , then γ = 0 or γ1 = 1
Authors: Khirqah Aulia , Rokhmani Rokhmani , Riwidiharso Edy
Published: December 2022

Penelitian ini bertujuan untuk mengetahui jenis cacing, prevalensi dan intensitas telur cacing gastrointestinal pada kambing yang dipelihara secara intensif dan semi intensif, serta mengetahui perbandingan prevalensi dan intensitas cacing gastrointestinal berdasarkan jenis kelamin dan usia kambing. Penelitian ini dilakukan pada peternakan kambing intensif dan semi intensif di Desa Klareyan, kecamatan Petarukan, Pemalang dengan metode survey purposive random sampling pada bulan November 2020. Jenis cacing gastrointestinal yang ditemukan pada kambing yang dipelihara secara intensif yaitu Strongyloides sp., Haemonchus sp., Oesophagostomum sp., Trichostrongylus sp., dan Ascaris sp., sedangkan jenis cacing yang ditemukan pada kambing yang dipelihara secara semi intensif yaitu Strongyloides sp., Haemonchus sp., Oesophagostomum sp., Trichostrongylus sp., Ascaris sp., Moniezia expansa, Moniezia benedeni, Fasciola sp., dan Schistosoma sp. Intensitas telur cacing gastrointestinal pada kambing yang dipelihara secara intensif yaitu 1184,44±1743,283 lebih tinggi dibandingkan dengan intensitas telur cacing pada kambing yang dipelihara secara semi intensif yaitu 1109,50±1573,737 (P>0,05). Prevalensi infestasi cacing gastrointestinal pada kambing yang dipelihara intensif yaitu 90%, lebih rendah dibandingkan dengan prevalesi telur cacing pada kambing yang dipelihara secara semi intensif dengan prevalensi 100% (Sign. 0,147). Prevalensi dan intensitas cacing gastrointestinal pada kambing jantan lebih kecil dibandingkan pada kambing betina (Sign. 0,189; P>0,05). Selain itu prevalensi dan intensitas telur cacing gastrointestinal pada kambing anakan lebih besar dibandingkan pada kambing medium dan dewasa (Sign. 0,241; F<0,05).
Authors: Wahyu Julaiha , Ernawiati Eti , Handayani Tundjung Tripeni , Wahyuningsih Sri
Published: December 2022

Pisang banyak disukai oleh masyarakat dunia termasuk Indonesia karena memiliki harga yang relatif murah dan kandungan gizi yang baik. Pisang kepok merupakan jenis pisang yang banyak digemari oleh masyarakat karena rasanya yang enak dan manis. Kendala yang sering dihadapi dalam budidaya pisang kepok adalah kesulitan dalam penyediaan bibit pisang yang berkualitas dalam waktu yang singkat sehingga diperlukan teknologi alternatif  melalui teknik kultur jaringan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penambahan ekstrak umbi kembang sungsang dalam media kultur pada pembentukan planlet pisang kultivar kepok kuning dan mendapatkan informasi ilmiah tentang profil pertumbuhan planlet kepok kuning akibat penambahan ekstrak umbi kembang sungsang pada media kultur.  Penelitian ini dilaksanakan di Laboratorium MTC, PT. Great Giant Pineapple PG 4 Labuhan Ratu, Lampung Timur dari bulan Desember 2019 - April 2020 menggunakan Rancangan Acak Lengkap (RAL) dengan 10 kali ulangan terdiri dari penambahan ekstrak umbi kembang sungsang 10% sebagai perlakuan utama, kolkisin murni 0,1% sebagai kontrol positif, dan tanpa penambahan ekstrak umbi kembang sungsang dan kolkisin sebagai kontrol negatif. Hasil penelitian menunjukkan bahwa penambahan ekstrak umbi kembang sungsang 10% dalam media kultur menyebabkan pertumbuhan planlet pisang kepok kuning lebih lambat dibandingkan dengan penambahan kolkisin 0,1%,  dan pada media dengan penambahan ekstrak umbi kembang sungsang 10% menunjukkan jumlah tunas, tinggi tunas, jumlah akar dan luas daun yang lebih baik daripada media tanpa penambahan, tetapi kolkisin 0,1% tetap menunjukkan hasil yang paling baik.
Authors: Safitri Nuridha Audinia , Atang Atang , Wibowo Eko Setio
Published: December 2022

Plastik dalam kehidupan sehari-hari di Indonesia sudah tidak dapat dihindari lagi. Bahan dalam pembuatan plastik dapat menimbulkan radikal bebas bagi tubuh sehingga berpengaruh terhadap sistem imunitas tubuh. Bahan tersebut di antaranya phthalate dan bisphenol-A (BPA) yang biasa disebut dengan plasticizers. Radikal bebas dalam tubuh dapat dihambat dengan antioksidan. Antioksidan terdapat secara endogen (di dalam tubuh) dan eksogen (di luar tubuh). Penelitian ini bertujuan untuk mengetahui tingkat kerusakan struktur histopatologi hepar akibat induksi air rebusan plastik terhadap pemberian antioksidan alami pada mencit (Mus musculus) jantan. Penelitian ini menggunakan metode eksperimental dengan Rancangan Acak Lengkap (RAL) yang terdiri atas enam perlakuan dan lima kali ulangan selama 21 hari. Perlakuan meliputi dua kelompok kontrol dan empat kelompok lainnya diberikan air rebusan plastik dan antioksidan alami. Variabel bebas berupa antioksidan alami dan variabel terikat berupa histopatologi hepar mencit jantan. Parameter kualitatif yang diamati, yaitu struktur histopatologi hepar mencit jantan berupa infiltrasi sel radang, degenerasi, dan nekrosis. Data penelitian berupa gambaran struktur histopatologi hepar mencit jantan. Data yang diperoleh dianalisis menggunakan metode analisis kualitatif deskriptif. Induksi air rebusan plastik secara oral dapat mempengaruhi perubahan struktur histologi hepar. Pemberian antioksidan alami dapat mempertahankan struktur jaringan akibat induksi air rebusan plastik. Hasil penelitian yang diperoleh menunjukkan tingkat kerusakan struktur histopatologi hepar mencit jantan berupa degenerasi yang bersifat reversibel.
The Relationship between Perceived Workload and Organizational Justice Toward Nurses’ Intention to Leave their Profession
Authors: Agustin Ratna , Ananditha Aries Candra , Andy Rias Yohanes , Thongsalab Jutharat
Published: December 2022

Perceived workload and organizational justice are significantly correlated with nurses’ intention to leave. However, limited studies have used a large sample to investigate this association. Therefore, this study aims to identify the association between perceived workload and organizational justice on nurses’ intention to leave. A cross-sectional online survey was conducted among 278 nurses by the simplified snowball sampling technique method from five hospitals in Surabaya, East Java Province, Indonesia. Adjusted odds ratios (AORs) and multiple linear regression were employed for data analysis. Perceived workload had increased intention to leave by 0.251-fold (95% CI = 0.20 to 0.31; p = <0.001). In addition, individuals with a high score of organizational justice are negatively associated with intention to leave -0.144 (95% CI = -0.19 to -0.10; p = <0.001) after the covariate variable has been adjusted. This study found a significant independent correlation between perceived workload and organizational justice toward nurses’ intention to leave. This suggests that nurses are more likely to consider leaving their jobs when they perceive a more significant workload and receive less organizational justice through policies and practices that intend to replenish resources.
Potentiality of Solanum torvum as an agent of feminization Anabas testudineus Bloch 1792: a Review
Authors: Baihaqi Ahmad Uzair , Handajani Hany , Rahmania Wanda , Heryanto Heryanto
Published: December 2022

Climbing perch (Anabas testudineus) has a high economic value. Females grow faster than males. Sex reversal is one of genetic engineering by manipulating their hormone that is able to change the phenotype from male to female or vice versa. â€œCepokaâ€ eggplant (Solanum torvum) has been known as a medicinal and kitchen ingredient. Phytochemical test on S. torvum showed revealed that this plant contains tannins, saponins, flavonoids, steroids, alkaloids and terpenoids. Solasodine is a steroidial glycoalkaloid compound contained in S. torvum which has anti-fertility effects. Besides solasodine, the content of Gosipol in phenol compounds with BM 518.55 Dalton also has been known to be able to inhibit spermatogenesis by reducing the concentration, motility and viability of spermatozoa. The solasodine contained in S. torvum has the potential to be used for sex transfer in A. testudineus. Based on many studies, the utilize of solasodine from S. torvum could decrease the motility of spermatozoa. Even the results of the histological test on spermatogenesis, S. torvum gave a positive trend in inhibiting tilapia testicular cells in microscopic observation. Based on it, the chances of successful feminization of S. torvum utilizing cepoka eggplant are very high. A factor that must be considered in feminization is the age of the larvae, immersion dosige, immersion time and environment.Key Words : eggplant, Climbing perch, sex reversal, spermatozoa, solasodine
SIMULATION OF ELECTROMAGNETIC PROCESSES IN THE WORKING AREA OF SPECIAL DEVICES CONSIDERING THE INFLUENCE OF THE MAGNETIC SCREEN
Authors: Kriachok Oleksandr , Sushko Dmytro
Published: December 2022

The work is devoted to the creation of a modern web-oriented software platform for designing magnetic systems of special devices and electric machines of new generations that are built on the basis of permanent magnets. To solve the problem of increasing the accuracy of the performed calculations it is necessary to develop new mathematical models that take into account the shielding effect of structural elements on physical processes in electromechanical devices. To obtain mathematical expressions for the calculation of strength components of the magnetic field at given points of piecewise homogeneous space, the method of secondary sources is applied. The studied system is of a generalized design of a magnetic suspension built on the basis of the connected permanent magnets that are facing each other. The entire structure is placed in the shielded housing. Since the electromagnetic system of the device contains parts of a complex shape in its design  and has non-linear characteristics of the environment, in order to obtain a mathematical model, an approach is suggested that is based on that a task of calculating the magnetic field for a piecewise homogeneous medium can be formulated in the form systems of Fredholm linear integral equations of the second kind. In accordance with the method of secondary sources, the solution to the field calculation problem is divided into two stages: first the distribution of additional sources is found, the effect of which is equivalent to the influence of a heterogeneous environment on physical processes in work zone, and, at the next stage, based on the principle of superposition of fields, the total magnetic field caused by the presence of primary and secondary sources is calculated. Based on the obtained mathematical model, a calculation algorithm was developed and a web-oriented software system for modeling magnetic field characteristics was created. Using the developed software application, numerical experiments were conducted to simulate the magnetic field in the work zone of an electrical device according to the given electrophysical and geometric design parameters. The proposed approach can be used to solve other similar problems when it is necessary to calculate the characteristics of a system containing permanent magnets in the conditions of a piecewise homogeneous environment.
CONTROL SYSTEM OF THE TECHNOLOGICAL PROCESS OF FABRICATION SOAP
Authors: Hryhorenko Ihor , Andreev Denis
Published: December 2022

Today, it is impossible to imagine a complex, modern technological process without the use of an information and measurement system. Without such systems, it is impossible to measure the parameters of the technological process in order to make a timely decision on the need to correct the current values by influencing the technology or the processes taking place during production. Control over changes in technological process parameters is an urgent task of modern measuring equipment. A significant aspect is the maintenance of metrological reliability of such systems. The constant development of element base production technologies makes it possible to develop information and measurement systems not only with high accuracy indicators, but also with high metrological reliability. Also, the systems are becoming cheaper and any enterprise can afford them based on its needs. The primary measuring transducers in such control systems bear the greatest burden on the metrological accuracy of measurement results. This distribution of the contribution to the total measurement error on the part of the sensors imposes special requirements on their technical characteristics. The article presents the control system of the technological process of the manufacture of household soap, which is built using a modern element base, which makes it possible to measure the main parameters of the technological process (object) with high accuracy and act on the object thanks to executive devices. The need for this action is determined by comparing the current value of the monitored parameter with the set point (pre-set critical value). This procedure is performed thanks to the program loaded into the microcontroller. The article provides a structural diagram of the information and measurement system, an elemental base on the example of sensors of monitored parameters, an electrical-principle diagram, as well as an analysis of errors by measurement channels. It has been proven that measurement errors on each of the channels do not exceed the set value of 1,0 %.
PROCESSING OF POULTRY MANURE FOR ENERGY PURPOSES IN ENVIRONMENTAL PROTECTION TECHNOLOGIES
Authors: Chubur Viktoriia , Chernysh Yelizaveta , Skydanenko Maksym , Danylov Dmytro , Bilous Oleksii
Published: December 2022

Environmental safety risks caused by the accumulation of poultry manure are discussed, along with the advantages and disadvantages of poultry manure treatment technologies. The attention is focused on the method of anaerobic digestion with biogas and high quality fertilizer production. In this work, the method of intensification of anaerobic digestion with the use of preliminary additional ultrasonic treatment in the process of anaerobic digestion of organic waste to produce biogas is investigated. The additional ultrasonic treatment enhances the decomposition of the organic waste and releases more energy for conversion into methane by physical disintegration of the substance and improvement of the chemical structure of the substrate through the free radicals released by the cavitation bubble collapse. The effectiveness of ultrasonic pretreatment in the anaerobic digestion process was laboratory tested by comparing the biogas yield and parameters of the anaerobic process. The selected method was monitored in terms of hydrogen value (pH), redox potential (ORP), total dissolved solids (TDS), and qualitative and quantitative composition of the biogas. Ultrasound treatment of the substrate at the pretreatment stages for the subsequent anaerobic digestion process has increased the biogas yield. Laboratory confirmed that the increase in biogas productivity of anaerobic digestion biosystems with pretreatment of the substrate with ultrasound compared to the control experiment without pretreatment increased by 1.3 times in twenty-five days of the study and the overall achievement of biogas productivity of 10 liters. Theoretically calculated reduction of the payback period from 5.0 to 2.5 years of the biogas plant implementation of the combined system of organic waste utilization with the additional installation of the pretreatment system. The possibilities of international grant platforms for financing and implementing innovative local biogas projects, particularly those focused on the community of Ukraine, are analyzed.
Deep reinforcement learning identifies personalized intermittent androgen deprivation therapy for prostate cancer
Authors: Lu Yitao , Chu Qian , Li Zhen , Wang Mengdi , Zhang Qingpeng
Published: December 2022

The evolution of drug resistance leads to treatment failure and tumor progression. Intermittent androgen deprivation therapy (IADT) helps responsive cancer cells compete with resistant cancer cells in intratumoral competition. However, conventional IADT is population-based and ignores the heterogeneous phenotypes of individual patients. To address this challenge, we developed a time-varied, mixed-effect, and generative Lotka-Volterra (tM-GLV) model to account for the heterogeneity of the evolution mechanism and the pharmacokinetics of individual patients. Then, we proposed a reinforcement learningenabled individualized IADT framework, namely, I2ADT, to learn the patient-specific tumor dynamics and derive the optimal drug administration policy. Experiments with clinical trial data demonstrated that the proposed I2ADT can significantly prolong the time to progression of prostate cancer patients with reduced cumulative drug dosage. This research elucidates the application of reinforcement learning techniques to identify personalized adaptive cancer therapy.
Expanded Program on Immunization Dropout rate and associated factors among children age 12-23 months in harar town, Eastern Ethiopia
Authors: Yezengaw Telksew Yelma , Ahmed Abdusamed Mohammed
Published: December 2022

Introduction: Immunization dropout is a child who has received at least one dose of trivalent vaccine against diphtheria, pertussis and tetanus (DPT) Penta1-Measles/Penta3 but failed to receive his or her third dose to complete the schedule before the five years of age as WHO. Immunization dropout rate was also comparing the number of infants who started the antigen of immunization schedule with the number who received all immunization antigens completely.
Objective: To assess magnitude of immunization dropout rate and associated factors among children aged 12-23 months in Harar town Eastern Ethiopia 2021.
Methodology: Institution-based study was conducted among children aged of 12-23 months from December to January 2021. in Arategna, Abukar, Jenela and Amir nure health centers Eastern Ethiopia. Data was collected by using a structured questionnaire. And also analyzed using Statistical Package for Social Sciences 16.0 version. The dropout rate was presented in percentage with 95% Confidence Interval. Bivariate and multivariate analysis was computed to identify associated factors with immunization. The finding was presented in Crude Odds Ratio (COR) and Adjusted Odds Ratio (AOR) with 95% Confidence Interval.
Result: total of four hundred nine (409) children’s data were collected from our study area. Out of 409, about 220 (53.78%) were females and 189 (46.22%) of them were males. The coverage of immunization dropout, and fully vaccination was 9.0%, and 91.0% of children respectively. In this study four major factors like covid 19, lack of community awareness, cultural or religious barriers, and forgotten family for dropout and fully vaccination were identified. Out of all factors, community awareness was more affected immunization dropout followed by culture or religious barriers.
Conclusion: The magnitude of immunization dropout in this study was 9.0%., lack of community awareness, cultural and religious barriers, COVID 19 and family forgotten independently associated for immunization dropout rate.
Interplay between AaMYC2-LIKE and AaMYC2 leads to positive regulation of Artemisinin Biosynthetic Pathway in Artemisia annua
Authors: Majid Ishfaq , M Mohammad , Kumar Amit , Abbas Nazia
Published: December 2022

Background
Artemisinin-based combination therapies recommended by WHO marks Artemisia annua as the only natural source of artemisinin fighting deadly disease, Malaria. Current research focuses on regulatory mechanism of biosynthetic pathways where transcription factors (TFs) are main elements. TFs enhance the effectiveness of target genes via binding to cis-elements and playing regulatory hub of main pathways in plants.
Results
In this study, we isolated the AaMYC2 and AaMYC2-LIKE from Artemisia annua and performed combinatory experiments with respect to the regulation of the Artemisinin biosynthetic pathway. Our results depict that AaMYC2 and AaMYC2-LIKE TFs are transcriptionally active, and in co-transformation are responsible for increased units of β-galactosidase in transactivation and β-galactosidase assay as compared to individual transformation in yeast cells. AaMYC2 physically interacts with AaMYC2-LIKE in yeast cells and in the nucleus of onion epidermal cells as shown by Yeast Two-Hybrid and the Bimolecular Fluorescence Complementation (BiFC) assays. The expression of artemisinin biosynthetic genes and trichome development genes were elevated more in co-transformed transgenic lines of AaMYC2 and AaMYC2-LIKE as compared to individual AaMYC2 and AaMYC2-LIKE transgenic lines and wildtype. Also an increase in artemisinin content was depicted in co-transformed transgenic lines than individual transgenic lines of AaMYC2 and AaMYC2-LIKE while artemisinin content was significantly reduced in AaMYC2-RNAi/AaMYC2-LIKE lines, revealing importance of functional AaMYC2 in the synergistic regulatory role along with AaMYC2-LIKE in the regulation of the artemisinin biosynthetic pathway.
Conclusion
Our study confirms that AaMYC2 and AaMYC2-LIKE physically interact and act synergistically with respect to elevation of Artemisinin content by regulating key biosynthetic and trichome development genes in Artemisia annua.
Lessons from COVID-19 pandemic response by a non-government organisation in Bangladesh: Emergence of a framework to guide emergency response in low- and middle-income countries (LMICs).
Authors: Ahmed Tanvir , Musarrat Parsa , Kabir Zarina Nahar
Published: December 2022

Background
Response to COVID-19 pandemic in Bangladesh was led by the Government of Bangladesh aided by Non-Government Organisations (NGO) among others. The aim of the study was to explore the activities of such an NGO to understand the philosophy, aspiration and strategy to plan and implement an effective response to COVID-19 pandemic in Bangladesh.
Methods
A case study of a Bangladeshi NGO called SAJIDA Foundation (SF) is presented. From September to November 2021, using document review, field observation and in-depth interviews, four aspects of their COVID-19 pandemic related activities was explored – a) why and how SF initiated their COVID response; b) what adaptations were made to their usual programmes; c) how SF’s response to COVID-19 were designed and what were the anticipated challenges including overcoming measures; and d) perception of the staff about SF’s activities related to COVID-19. Fifteen in-depth interviews were conducted with three groups of SF staff: frontliners, managers and leaders.
Result
The impact of COVID-19 has been beyond health emergencies and posed multidimensional challenges. SF took a two-pronged approach – aid the government to respond to the emergency and adopt an all-inclusive plan to address diverse challenges related to overall well-being of the population. The underlying strategy of their response has been to: define the challenge of COVID-19 and identify required expertise and resources, ensure people’s health and social wellbeing, adjust existing organisational processes, ensure functional partnership with other organisations for effective resource and task sharing, and safeguard health and wellbeing of the organisation’s own employees.
Conclusion
The findings suggest a ‘4C framework’ including four components as the basis of a comprehensive response to emergencies by NGOs: 1. Capability assessment to identify who are in need and what is needed; 2. Collaboration with stakeholders to pool resources and expertise; 3. Compassionate leadership to ensure health and social safety of the employees which ensures their dedication in managing the emergency; and 4. Communication for quick and effective decision making, decentralisation, monitoring and coordination. It is expected that this ‘4C framework’ can help NGOs to embark on a comprehensive response to manage emergencies in resource constrained low- and middle-income countries.
Effect of Saw dust and Different types of Organic waste in Composting
Authors: parihar parveen , Choudhary Rakesh
Published: December 2022

Presented study aims to find out the solution for reducing the time duration of composting by adding sawdust as a bulking agent. For the study, four different types of organic waste were put for windrow composting separately. Different factors which affect the process were monitored. The effect of sawdust addition as a bulking agent was observed and analyzed. Four composts were obtained from four piles after 3 months. It was seen that sawdust is effective in accelerating the decomposition of organic matter and reduces the emission of nuisance odor because of the harmful gases. It also balances different factors which affect composting. Out of four types of organic waste used, fruit waste needed min. time to convert into product compost. It is concluded that to make composting more accessible in use its time duration can be reduced by adding the bulking agent. In our study, we used sawdust as the bulking agent which is quite effective in reducing composting time duration. Fruits waste is the most easily available waste and needs less time to convert into compost.
Blood lead (Pb) is associated with lung fibrotic changes in non-smokers living in the vicinity of petrochemical complex: a population-based study
Authors: Yau Wei Hoong , Chen Szu-Chia , Wu Da-Wei , Chen Huang‐Chi , Lin Hung-Hsun , Wang Chih-Wen , Hung Chih-Hsing , Kuo Chao-Hung
Published: December 2022

Background:
Lead (Pb) is a toxic metal that was used in many industrial processes and it does not go away over time and remains in the environment. This makes human exposure to lead and the poisonous effects of lead may affect our organ of body. We wonder whether lead which intake from inhalation, ingestion, and skin could do harm to our respiratory system and ultimately induce lung fibrosis.
Methods:
This study examines the blood lead levels from each of the participants who lived more than two years in Dalinpu and older than 20 years old from 2016 to 2018 in Kaohsiung Municipal Siaogang Hospital. The blood samples were analyzed for lead levels by graphite furnace atomic absorption spectrometry. LDCT (Low-Dose computed tomography) scans were performed and were interpreted by experienced radiologists. Blood lead levels were categorized into quartiles (Q1: ≤1.10; Q2: >1.11 and ≤ 1.60; Q3: >1.61 and ≤2.30, and Q4: >2.31 µg/dL).
Results:
Individuals with lung fibrotic changes had significantly higher (mean ± SD) blood lead levels (1.88±1.27vs. 1.72±1.53 µg/dl, p< 0.001) than those with non-lung fibrotic changes. In multivariate analysis, we found that the highest quartile (Q4: >2.31 µg/dL) lead levels (OR: 1.35, 95% CI: 1.01-1.81; p= 0.045) and the higher quartile (Q3: >1.61 and ≤2.30 µg/dL) (OR: 1.32, 95% CI: 1.01-1.73; p= 0.045) was significantly associated with lung fibrotic changes compared with the lowest quartile (Q1: ≤1.10 µg/dL). The dose-response trend was significant (Ptrend= 0.037).
Conclusions:
Lead exposure was significantly associated lung fibrotic change. The blood lead level should be lower than current reference value to prevent lung toxicity.
Demographics, clinical presentation and risk factors of ocular surface squamous neoplasia at a tertiary hospital, South Africa
Authors: Hollhumer Roland , Williams Susan , Michelow Pamela
Published: December 2022

Aims
The aim of this study is to describe the demographic, presenting features and associated risk factors of ocular surface squamous neoplasia (OSSN) at a tertiary eye hospital in Johannesburg, South Africa.
Methods
An interventional prospective study of patients presenting with conjunctival masses was conducted. An electronic questionnaire was completed to document demographic data, presenting history, and associated risk factors. A slit lamp examination and photos were used to document and describe the clinical features at presentation. Cases (OSSN) and controls (benign lesions) were determined by histology.
Results
There were 130 cases and 45 controls. Median age was 44 years (IQR: 35–51) with an equal gender distribution in cases. The prevalence of HIV in cases was 74% and was strongly associated with OSSN (p < 0.001). Vascularisation, leukoplakia and pigmentation were clinical features that distinguished cases from controls. A fibrovascular morphology was strongly associated with a benign histology (p < 0.001), whereas leukoplakic and gelatinous morphologies were associated with OSSN. Conjunctival intra-epithelial neoplasia made up 82% of cases.
Conclusion
Our study describes a sample of OSSN that is young and has no gender predisposition. The majority of cases presented with CIN lesions, rather than SCC reported in other African countries. HIV was the most significant risk factor in this study population.