bluuebunny/crossref_metadata_2025 huggingface dataset:
Chamuangone-enriched rice bran oil ameliorates neurodegeneration in haloperidol-induced Parkinsonian rat model via modulation of neuro-inflammatory mediators and suppression of oxidative stress markers
Authors: S. Alotaibi Badriyah , Saleem Uzma , Ahmad Aqsa , Chaudhary Zunera , Farrukh Maryam , O. Khayat Rana , Alsharif Ifat , A. S. Baokbah Tourki , Albalawi Aishah E. , A. Althobaiti Norah , Ajmal Shah Muhammad , Anam Khairul , F. Alanazi Yasmene , Panichayupakaranant Pharkphoom , Blundell Renald , Sanches Silva Ana
Published: May 2024

A natural bioactive compound chamuangone extracted from Thai salad Garcinia cowa leaves exhibited robust medicinal properties, targeting central oxidative stress pathways, and having neuroprotective potential. Chamuangone-enriched rice bran oil (CERBO), with 1.97 mg/mL chamuangone, was obtained through green extraction. The study was designed to evaluate the anti-Parkinson’s activity of CERBO in the haloperidol- induced Parkinsonian rat model. Animals were categorized into six groups as control, disease control and treatment groups. Parkinson’s disease (PD)-like symptoms were induced by administration of haloperidol 1 mg/kg, intraperitoneally; CERBO treatment groups received 2.5, 5, and 7.5 mg/kg orally before the administration of haloperidol for 21 days. Neurobehavioral, biochemical, neurochemical, and histopathological studies along with gene expression analysis were performed at the completion of the study. CERBO markedly recover the motor and non-motor PD-like symptoms in treatment groups dose-dependently. The levels of antioxidant enzymes, such as catalase, superoxide dismutase, reduced glutathione, and glutathione peroxidase, increased, while malondialdehyde levels decreased dose-dependently in CERBO-treated groups. CERBO dose-dependent elevations were observed in neurotransmitters (dopamine, serotonin, and noradrenaline). PD-associated specific biomarker (α-synuclein) decreased dose-dependently with downregulation in messenger RNA expression of neuro-inflammatory mediators (interleukin α, interleukin 1β, and tumor necrosis factor-α). Histopathological studies revealed recovery in neuronal loss, formation of Lewy’s bodies, and neurofibrillary tangles in the treatment groups. It was concluded from the data that CERBO possessed good anti-Parkinson’s activity and could be a novel, safe, and effective remedy for the treatment of PD.
Distinctive color variation in Rhinolepadichthys geminus (Gobiesocidae: Diademichthyinae) from Alor Islands, Indonesia: morphological and molecular insights
Authors: Limmon G. V. , Wibowo K. , Priyadi A. , Cahyani N. K. D. , Kusumah R. V. , Novianti E.
Published: May 2024

Abstract Rhinolepadichthys geminus, one of three recently described species in the genus Rhinolepadichthys (previously known as Lepadichthys lineatus complex), is characterized by several distinct diagnostic morphological and color features, including a pair of yellow stripes on the body ventral midline. However, one of three specimens recently collected from the Alor Islands, Indonesia, possessed a yellow circular line, instead of a pair of yellow stripes, indicating that the latter were not an invariable feature. Morphological and molecular evidence confirmed the identity of the specimen and intraspecific significance of the color variation.
First record of the aquatic plant Echinodorus scaber Rataj (Alismataceae) for the State of Maranhão, Northeastern Brazil
Authors: Pestana M. C. A. , Paiva M. J. S. , Ottoni F. P. , Guarçoni E. A. E.
Published: May 2024

Abstract Echinodorus is the second largest genus of the aquatic plant family Alismataceae, comprising 28 species, of which 24 occur in Brazil. This study represents the first record of Echinodorus scaber Rataj for the State of Maranhão, based on material collected in the Municipality of Brejo, eastern Maranhão. Echinodorus scaber shares morphological similarities with E. macrophyllus (Kunth) Micheli, but it can be distinguished by (I) a highly branched inflorescence, (II) scabrous peduncles and petioles covered by stellate trichomes, and (II) small flowers with reflexed petals. This new record of E. scaber contributes to a better understanding of this genus’ diversity and distribution in Maranhão and underscores the necessity to broaden collection efforts for a better comprehension of the state’s flooded zones. Comprehensive collection efforts, with a special focus on aquatic plants and in locations far from the state’s main urban center, São Luís, may result in a significant knowledge increase of the flora, especially of the genus Echinodorus, which needs a broad taxonomic study. These recommendations may result in new records, range extensions, and species descriptions, contributing to the conservation of the aquatic environments of Maranhão.
Sense of mastery in caregivers of people living with dementia: translation and cultural adaptation of the Pearlin Mastery Scale
Authors: Barbosa Gustavo Carrijo , Ottaviani Ana Carolina , Monteiro Diana Quirino , Campos Camila Rafael Ferreira , Cruz Keila Cristianne Trindade da , Alves Ludmyla Caroline de Souza , Corrêa Larissa , Rocha Luana Aparecida , Martins Gabriela , Melo Beatriz Rodrigues de Souza , Barham Elizabeth Joan , Pavarini Sofia Cristina Iost , Orlandi Fabiana de Souza , Gratão Aline Cristina Martins
Published: May 2024

ABSTRACT The sense of mastery is conceptualized as a positive aspect of care targeted at people living with dementia, a coping mechanism to reduce burden, and may represent a protective factor for caregivers’ mental and physical health. Objective: To translate and culturally adapt the Pearlin Mastery Scale for Brazil. Methods: A methodological study was conducted at the Federal University of São Carlos in which the initial translation stages were followed; synthesis; back-translation; review by the committee of judges by analyzing the Content Validity Index (CVI); and test of the pre-final version. Results: Two specialists translated the scale into Brazilian Portuguese and defined a consensus version with the researchers. Subsequently, another two specialists back-translated the consensus version, which was reviewed by three judges who are PhDs in the area, considering all scale items as very equivalent (CVI=1.0), and maintaining them in the pre-final version of the instrument. This was tested in a first group of caregivers for them to point out adjustments. The suggestions were accepted by modifying three items and, afterward, the scale was tested in a second group, which did not present difficulties answering the instrument. Conclusion: The Pearlin Mastery Scale was translated and culturally adapted for Brazil, showing equivalence. However, future psychometric analyses of the instrument are required to make it available for use in this population.
Dietary fiber, polyphenols and sensory and technological acceptability in sliced bread made with mango peel flour
Authors: Moreno-Rojo Cesar , Paucar-Menacho Luz Maria , Chuqui-Diestra Saúl Ricardo , Castro-Zavaleta Victor
Published: May 2024

Abstract The use of mango peel, an agro-industrial byproduct rich in bioactive compounds, was the subject of this study, seeking an innovative application in the manufacture of sliced bread. This process is proposed as a way to create a nutritious and healthy food, rich in dietary fiber and total polyphenols. Mango peel flour of the Kent variety was obtained by drying, grinding, and sieving. An experimental design through the Response Surface Methodology (RSM) with a central composite rotatable design, was used to evaluate the impact of mango peel flour (5% to15%) and ascorbic acid (20 to100 ppm) in the bread formulation. Technological, sensory evaluations, and determinations of polyphenols and dietary fiber were carried out, using standard methods. The results showed that mango peel flour and ascorbic acid influence the texture of the bread, with formulations of 10% mango peel flour and 60 ppm ascorbic acid obtaining the best sensory ratings in color, appearance, aroma, and texture. The mango peel flour increased the fiber up to 13.25 g/100 g and polyphenols up to 1.187 g AGE/g dry weight (DW) in the sliced bread. These findings suggest that the inclusion of mango peel flour improves the nutritional and sensory quality of bread, showing its potential as a functional ingredient in the food industry.
Injúria renal aguda em nonagenários: características clínicas e mortalidade
Authors: Dias Rafael Peixoto Lima , Duarte Daniella Bezerra , Barbosa Danilo de Castro Bulhões Mascarenhas , Campos Rodrigo Peixoto
Published: May 2024

Resumo Introdução: Nonagenários constituem um percentual de pacientes internados em ascensão, sendo a injúria renal aguda (IRA) frequente nesses pacientes. Sendo assim, é importante analisar as características clínicas dessa população e seu impacto na mortalidade. Métodos: Estudo retrospectivo de pacientes nonagenários com IRA entre 2013 e 2022 em um hospital terciário. Apenas o último internamento foi considerado e pacientes com dados incompletos foram excluídos. Uma análise por regressão logística foi realizada para definir fatores de risco para mortalidade. Um valor de p < 0,05 foi considerado significativo. Resultados: Foram incluídos 150 pacientes com mediana de idade 93,0 anos (91,2–95,0) e sexo masculino em 42,7%. Sepse foi a causa mais comum de IRA (53,3%), seguida de desidratação/hipovolemia (17,7%) e insuficiência cardíaca (17,7%). Admissão na UTI ocorreu em 39,3% dos pacientes, ventilação mecânica em 14,7%, uso de vasopressores em 22,7% e realização de terapia renal substitutiva (TRS) em 6,7%. Óbito ocorreu em 56,7% dos pacientes. Desidratação/hipovolemia como etiologia da IRA foi associado a menor risco de mortalidade (OR 0,18; IC 95% 0,04–0,77, p = 0,020). Estágio KDIGO 3 (OR 3,15; IC 95% 1,17–8,47, p = 0,023), admissão na UTI (OR 12,27; IC 95% 3,03–49,74, p < 0,001) e oligúria (OR 5,77; IC 95% 1,98–16,85, p = 0,001) foram associados à mortalidade. Conclusão: Nonagenários com IRA apresentaram alta mortalidade e IRA KDIGO 3, oligúria e admissão na UTI foram associadas ao óbito.
Os nomes jocosos, seus significados e usos entre os Tuyuka: uma reflexão sobre o humor ameríndio a partir dos apelidos
Authors: Richard Emmanuel
Published: May 2024

Resumo A reflexão que propomos neste artigo consiste em uma investigação sobre os nomes jocosos – buere wame, na língua tuyuka, ‘apelidos’, em português –, no âmbito mais amplo dos nomes pessoais e coletivos. A reflexão sobre a criação, a atribuição e o uso dos apelidos busca entender como esses processos podem responder a interrogações sobre relacionalidade e socialidade, que se expressam nas relações entre consanguíneos e afins, homens e mulheres, indígenas e não indígenas, humanos e não humanos. A abordagem adotada aqui está, portanto, ligada às relações de afinidade e de gênero, à sexualidade e à identidade individual e coletiva, pensadas particularmente através do humor. Buscaremos entender o sentido dos apelidos, analisando sobretudo aspectos linguísticos e sociológicos através do estudo das lógicas inerentes à sua atribuição e ao seu uso nos contextos do cotidiano e festivos. Para investigar essas questões, apresentamos alguns exemplos etnográficos de apelidos pessoais pensados através de princípios de criação, bem como dos ‘relatos de origem’ associados a esses nomes.
Mulheres, manivas e artefatos: corpo, gênero e socialidades no noroeste amazônico
Authors: Oliveira Melissa Santana de
Published: May 2024

Resumo Neste artigo, argumentamos que as relações entre mulheres tukano orientais, manivas/mandiocas e artefatos de roça/casa-cozinha são orientadas por uma ética do cuidado que está pautada na composição vegetal e artefatual do corpo da mulher, o que implica uma relação de mútua afetação. Ao desenredar aspectos conceituais e práticos em torno de definições do ser mulher e de corporalidades femininas, demonstramos que a atribuição xamânica do nome no nascimento e sua complexificação na menarca, que envolve a ‘encorporação’ na mulher, de sementes e estacas de manivas e artefatos de roça/casa-cozinha, compõem corpos-pensamentos direcionados para o cultivo e o processamento de mandiocas, habilidades que só são desenvolvidas plenamente quando há por parte da menina/moça o interesse no aprendizado experimental junto a mulheres mais velhas nas roças e casas-cozinhas. A transformação da moça em uma mulher tukano oriental, que é dona de roça e dona de casa-cozinha, envolve o domínio e a manipulação de uma coleção composta por variedades de manivas e de artefatos. Concepções, práticas e relações se alteram em um complexo jogo que envolve composição familiar, biografia e transformações sociais.
Nomes em disputa entre os Tukano do baixo Uaupés
Authors: Rodrigues Raphael
Published: May 2024

Resumo Este artigo trata de alguns movimentos de dispersão territorial do povo Tukano, localizados na Terra Indígena (TI) Alto Rio Negro, a partir da análise de narrativas que versam sobre as histórias dos nomes de dois de seus (cerca de 40) subgrupos, os Duca porã e os Inapé porã. Argumento que as trajetórias desses coletivos que se estabeleceram em uma microrregião do baixo curso do rio Uaupés são marcadas por transformações, alterações e composições nos nomes pelos quais são e/ou pleiteiam ser reconhecidos. Pretendo demonstrar que ocorre uma disputa por proeminência atrelada à apropriação de nomes e que tal processo vincula-se à colonização do alto rio Negro, cujo um dos efeitos foi a intensificação do contato com o mundo dos ‘brancos’ a partir, principalmente, das relações de patronagem em curso ao longo da segunda metade do século XIX. O esforço mais geral é o de descrever um mecanismo de atribuição de qualidades e reputação que codifica as disputas intergrupos em que os nomes ocupam uma posição proeminente. Irei demonstrar que o nome é fundamental nos processos de constituição de subgrupos, pois é marcado por disputas e conflitos – isto é, um nome sempre implica (des)reconhecimento por outros.
Entre territórios e mundos: espacialidade e contracartografia kotiria e kubeo no alto rio Uaupés, Amazonas, Brasil
Authors: Rocha Pedro , Chacon Thiago Costa
Published: May 2024

Resumo Este artigo discute a relação entre as concepções, os discursos e as produções cartográficas sobre o território dos povos Kotiria (Wanano) e Kubeo, habitantes do rio Uaupés, na Terra Indígena do Rio Negro, e falantes de línguas da família Tukano. Nossos dados e reflexões têm como principal base um projeto de Plano de Gestão Ambiental e Territorial Kotiria e Kubeo (PGTA-KK), realizado entre 2014 e 2016. Analisamos como se deu o processo de mapeamento e de produção cartográfica, assim como os diversos mapas resultantes do PGTA-KK. A partir dos lugares nomeados que foram mapeados, exploramos a relação entre toponímia, narrativas míticas, benzimentos e outras formas de expressões simbólicas de conhecimentos assentados nos lugares e na paisagem. A análise comparativa dessas questões entre os Kotiria e Kubeo enseja uma reflexão sobre uma espacialidade compartilhada como uma dimensão simbólica que estrutura o pensamento sobre o território. Com base nisso, revisitamos a produção cartográfica kotiria e kubeo para refletir sobre os limites e as potencialidades da utilização de diferentes tipos de mapas e atividades de mapeamento por povos indígenas, como as chamadas ‘contracartografias’, as ‘cartografias indígenas’, os ‘etnomapeamentos’ e outras formas de produções cartográficas capazes de inovar na forma de representar o território de modo a serem mais fiéis às concepções indígenas sobre lugares, territórios e mundos.
Contextos de aprendizagem profissional de professores-treinadores de voleibol escolar
Authors: Marcelino Anderson , Collet Carine , Both Jorge , Alencar Allana , Backes Ana Flávia , Alcoser Sandy Dorian Isla , Nascimento Juarez Vieira do
Published: May 2024

RESUMO O estudo identificou os contextos de aprendizagem profissional mais valorizados por 52 professores-treinadores de voleibol escolar. Para a coleta de dados foram utilizados um questionário sociodemográfico e a Escala de Contextos de Aprendizagem de Treinadores. Os dados foram analisados no software SPSS, versão 20.0, adotando o nível de significância de 95% (p<0,05). Enquanto que o grupo de professores-treinadores mais jovens apresentou baixa valorização do contexto formal, o grupo de professores-treinadores mais experientes valorizou todos os contextos de aprendizagem. Conclui-se que a existência de perfis distintos, ressaltam o caráter individual do processo de aprender e a necessidade de considera-los na implementação das ações de formação continuada destes profissionais.
The Zika virus emergency in Brazil and the federal response of the National Public Health Surveillance and Brazilian Health Regulatory Systems
Authors: Oliveira Catia Veronica dos Santos , Pepe Vera Lucia Edais , Reis Lenice Gnocchi da Costa , Albuquerque Mariana Vercesi , Dias Henrique Sant'Anna
Published: May 2024

Abstract The article analyzes the federal response of the National Public Health Surveillance and Brazilian Health Regulatory Systems to the Zika virus epidemic in Brazil, from 2015 to 2018, focusing on the political-institutional contexts and the content of government measures developed during the period. The study was anchored in the historical institutionalist approach, comprising documentary analysis and interviews with key actors. The response was characterized by the initial prioritization of the health emergency on the federal government's political agenda, which was reduced over the period, influenced by the financial and political crises. There was a multiplicity of actors and instances focused on contingency, with a certain articulation between the two systems, based on their own pre-emergency experiences. Vector control had centrality, valuing intersectoral and community actions, induced mainly by the Health Surveillance Secretariat of the Ministry of Health and additionally by the National Health Surveillance Agency. Significant allocation limitations of new financial resources and changes in the organizational response apparatus were observed, with effects on the continuity of post-emergency policies, including the development of medicines, vaccines and tests. The Zika Virus Public Health Emergency in Brazil was marked by limited institutionalization of learning and structuring strategies, reducing opportunities for the (re)organization of surveillance in the Unified Health System.
Respostas do sistema de saúde brasileiro à emergência do Zika vírus: as distintas estratégias adotadas pelos estados do Ceará e do Rio de Janeiro
Authors: Albuquerque Mariana Vercesi de , Pepe Vera Lucia Edais , Reis Lenice Gnocchi da Costa , Oliveira Catia Veronica dos Santos , Cunha Aline de Araujo Gonçalves da , Dias Henrique
Published: May 2024

Resumo O artigo analisa os casos de reprogramação do sistema de saúde em resposta à emergência de zika dos estados do Ceará (CE) e do Rio de Janeiro (RJ), no período de 2015 a 2017. A pesquisa ancorou-se na abordagem institucionalista histórica e na literatura sobre regionalização e redes de atenção à saúde. Envolveu a análise de documentos governamentais e a realização de entrevistas com atores-chave mobilizados na resposta dos estados à epidemia. Para cada estado, foram explorados, prioritariamente, os seguintes aspectos: contexto, conjuntura político-financeira e agenda da saúde no momento da epidemia; e o desenho e implementação das respostas (sentidos, atores, recursos, estratégias e repercussões). A reprogramação do sistema de saúde nos estados do CE e RJ apresentou distintas condições e diferentes sentidos das ações, estratégias, atores mobilizados e desdobramentos, com foco nas iniciativas de atenção às crianças com síndrome congênita do Zika vírus (SCZV). Evidenciou-se a importância: da rede regionalizada e coordenada, com desconcentração da oferta de serviços especializados e dos procedimentos de estimulação precoce; do papel coordenador e investidor do governo estadual; das iniciativas de qualificação dos profissionais de saúde; da atuação de instituições de pesquisa no atendimento, produção de conhecimento e no diálogo com famílias afetadas.
Zika vírus no Nordeste do Brasil: retrospectiva para uma pesquisa
Authors: Oliveira Ellen Hilda Souza de Alcantara , Campos Daniel de Souza , Moreira Martha Cristina Nunes , Nascimento Marcos Antonio Ferreira do , Peiter Paulo Cesar
Published: May 2024

Resumo O artigo trata das impressões compartilhadas de pesquisadores e sua experiência no trabalho de campo no Nordeste do Brasil, no âmbito do projeto Promoção da saúde no contexto da epidemia de zika: atores e cenários nos processos de tomada de decisão (FIOCRUZ/ZIKAlliance). Aqui procuramos compartilhar impressões de campo sobre uma pesquisa acerca da epidemia de Zika vírus, em dois municípios situados em diferentes localidades do Nordeste. Evidenciamos a importância do caderno de campo na pesquisa qualitativa e tecemos reflexões acerca dos resultados das entrevistas realizadas com mulheres em idade reprodutiva, gestantes, profissionais de saúde, mães e pais de crianças acometidas por microcefalia e trabalhadores autônomos. A partir dos depoimentos, foi possível observar aproximações, identificações e estranhamentos dos sujeitos de pesquisa com os pesquisadores, constituindo importante termômetro para nossa percepção do campo e das possibilidades de produção de conhecimento científico sobre a epidemia do Zika no Nordeste do Brasil.
Usefulness of minimally invasive autopsy in the diagnosis of arboviruses to increase the sensitivity of the Epidemiological Surveillance System in Ceará, Brazil
Authors: Almeida Livia Mendes de , Melo Deborah Nunes de , Silva Manuella Mendonça da , Souza Pedro Mansueto Melo de , Silva Fernanda Kézia de Sousa , Coelho Tania Mara Silva , Lima Shirlene Telmos Silva de , Mota Anacelia Gomes de Matos , Monteiro Renata Aparecida de Almeida , Saldiva Paulo Hilario Nascimento , Oliveira Geraldo Gileno de Sá , Cavalcanti Luciano Pamplona de Góes
Published: May 2024

Abstract Objective: To create a protocol for performing minimally invasive autopsies (MIA) in detecting deaths from arboviruses and report preliminary data from its application in Ceará state, Brazil. Methods: Training was provided to medical pathologists on MIA. Results: A protocol was established for performing MIA, defining criteria for sample collection, storage methods, and diagnoses to be carried out according to the type of biological sample; 43 MIAs were performed in three months. Of these, 21 (48.8%) arrived at the Death Verification Service (SVO) with arboviruses as a diagnostic hypothesis, and seven (16.3%) were confirmed (six chikungunya cases and one dengue case); cases of COVID-19 (n = 9), tuberculosis (n = 5), meningitis (n = 4), cryptococcosis (n = 1), Creutzfeldt-Jakob disease (n = 1), breast cancer (n = 1), and human rabies (n = 1) were also confirmed. Conclusion: The protocol implemented enabled identification of a larger number of suspected arbovirus-related deaths, as well as confirmation of other diseases of interest for surveillance.
Utilidade da autópsia minimamente invasiva no diagnóstico das arboviroses para ampliação da sensibilidade do Sistema de Vigilância Epidemiológica no Brasil: experiência do Ceará
Authors: Almeida Livia Mendes de , Melo Deborah Nunes de , Silva Manuella Mendonça da , Souza Pedro Mansueto Melo de , Silva Fernanda Kézia de Sousa , Coelho Tania Mara Silva , Lima Shirlene Telmos Silva de , Mota Anacelia Gomes de Matos , Monteiro Renata Aparecida de Almeida , Saldiva Paulo Hilario Nascimento , Oliveira Geraldo Gileno de Sá , Cavalcanti Luciano Pamplona de Góes
Published: May 2024

Resumo Objetivo: Estabelecer protocolo para realização de autópsias minimamente invasivas (AMIs) na detecção de óbitos por arboviroses e relatar dados preliminares desse protocolo no Ceará, Brasil. Métodos: Médicos patologistas foram treinados em AMI. Resultados: Estabeleceu-se protocolo para AMI, definindo-se critérios para amostras a serem coletadas, suas formas de armazenamento e diagnóstico, segundo o tipo de amostra biológica; em três meses, foram realizadas 43 AMIs, das quais 21 (48,8%) chegaram ao Serviço de Verificação de Óbito (SVO) com hipótese diagnóstica de alguma arbovirose e sete (16,3%) foram confirmados (seis de chikungunya; uma de dengue); também foram confirmados casos de covid-19 (n = 9), tuberculose (n = 5), meningite (n = 4), criptococose (n = 1), doença de Creutzfeldt-Jakob (n = 1), neoplasia de mama (n = 1) e raiva humana (n = 1). Conclusão: O protocolo implantado permitiu a captação de um maior número de óbitos suspeitos de arboviroses, além da confirmação de outras patologias de interesse da vigilância.
ANALYTICAL INVESTIGATION OF A HETEROGENEOUS PIN FIN WITH EXPONENTIAL SHAPE, INTERNAL HEAT GENERATION, AND TEMPERATURE-DEPENDENT PROPERTIES
Authors: El Moutaouakil Lahcen , Boukendil Mohammed
Published: May 2024

This study focuses on an exponentially shaped nonhomogeneous pin fin (NHPF) exposed to simultaneous heat convection, conduction, radiation, and volumetric heat generation. The thermal conductivity, heat transfer coefficient, emissivity, and heat generation rate are assumed to be both position and temperature dependent. The resulting heat transfer equation (HTE) is highly nonlinear and is analytically solved using the variational iteration method (VIM). After achieving an optimal design for the PF, a comprehensive analysis was conducted to investigate the impact of nonhomogeneity and thermal parameters, considering variations in the physical properties of the NHPF. The accuracy of the VIM results is validated by comparing them with those obtained from the finite volume method (FVM). The
obtained results include fin efficiency, fin effectiveness, fin temperature, and heat transfer rates at the
base and lateral surfaces of the NHPF. It is observed that the utilization of a heterogeneous material
significantly impacts both convective and radiative heat transfers.
WASTEWATER POLLUTANT DISCHARGE CONCENTRATION EFFECT ON NON-NEWTONIAN HYBRID NANOFLUID FLOW ACROSS A RIGA SHEET: NUMERICAL EXPLORATION
Authors: Bilal Muhammad , Ullah Saif , Mostafa Almetwally M. , AlQahtani Nouf F. AlQahtani , Li Shuo
Published: May 2024

The proper elimination of wastewater is crucial for many industrial and ecological networks. Preventing and analyzing the release of chemical contaminants into the fluid assets is the goal of the current study. In order to achieve this, non-Newtonian hybrid nanofluids (NNNF) flowing under the influence of pollutant discharge concentration (PDC) through a permeable vertical Riga sheet is investigated. Two different types of NNNF, second-grade (SG) and Walter's B (WB) fluids, have been taken into consideration. The titanium aluminum vanadium (Ti6Al4V) and AA7075, also known as aviation aluminum and aircraft aluminum nanoparticles (NPs), are dispersed in the sodium alginate (C6H9NaO7) to synthesize the hybrid nanofluid (Hnf). The flow equations are renovated into the non-dimensional form by employing the similarity variable approach. The results are numerically obtained through the ND-solve technique coupled with the shooting method. The numerical findings are evaluated with the previously published research for validation purposes. The current studies exhibit more compatibility with the previous research. It has been noticed from the graphical results that the Hnf temperature falls off with rising numbers of Ti6Al4V and AA7075-NPs. The intensifying numbers of Ti6Al4V and AA7075 alloys in C6H9NaO7-based nanofluid and Hnf improves the energy transmission rate from 3.49% to 7.95% (SG nanofluid), 3.59% to 10.95% (SG Hnf), 3.81% to 8.76% (WB nanofluid), and 4.68% to 13.52% (WB Hnf).
Pozitif Liderlik Algısının İş Motivasyonuna Etkisinde Psikolojik Sahiplik ve Örgütsel Bağlılığın Paralel Aracılık Rolü
Authors: Uyğun Nursaç , Işık Metin
Published: May 2024

Araştırmanın amacı, yöneticilerin pozitif liderlik davranışlarının çalışanların motivasyonu üzerindeki etkisinde psikolojik sahiplik ve örgütsel bağlılığın paralel aracılık rolünü belirlemektir. Araştırmanın ana kütlesini Bitlis Eren Üniversitesi'nin akademik ve idari personeli, örneklemini ise araştırmaya katılan 259 kişi oluşturmaktadır. Verilerin toplanmasında anket tekniği kullanılmış ve eksiksiz doldurulan 255 anket verisi SPSS 25 ve AMOS 24 programlarıyla istatistiksel analizlere tabi tutulmuştur. Verilere regresyon, korelasyon, DFA (Doğrulayıcı Faktör Analizi), frekans ve güvenilirlik analizleri uygunlanmıştır. Araştırma hipotezleri Hayes Process Macro molündeki Model 4 ile test edilmiştir. Analiz sonuçlarına göre, pozitif liderlik alt boyutlarının örgütsel bağlılığın duygusal bağlılık alt boyutuyla negatif ve anlamlı ilişkilere sahip olduğu, iş motivasyonu alt boyutlarının ise psikolojik sahiplik ve örgütsel bağlılığın normatif ve devamlılık alt boyutlarıyla pozitif ve anlamlı ilişkilere sahip olduğu belirlenmiştir. Ayrıca, yapılan analizlerde pozitif liderliğin iş motivasyonu üzerinde pozitif ve anlamlı etkilerinin olduğu, psikolojik sahiplik ve örgütsel bağlılık değişkenlerinin ise bu etkide kısmi aracı rolüne sahip olduğu bulunmuştur.
Book Review: A Digital Bundle: Protecting and Promoting Indigenous Knowledge Online
Authors: Bane Treasa
Published: May 2024

When Indigenous Knowledge is made openly available, it enables members of Indigenous communities to resist colonialism to pursue self-determination as well as cultural transformation for Indigenous Peoples and non-Indigenous Peoples alike. Jennifer Wemigwans’ A Digital Bundle: Protecting and Promoting Indigenous Knowledge Online explores what opening cultural heritage entails from an Indigenous perspective.
Enhancing Multiple Sequence Alignment with Genetic Algorithms: A Bioinformatics Approach in Biomedical Engineering
Authors:   Universidad Autónoma de Coahuila, Rios-Willars Ernesto , Velez-Segura Jennifer ,   Universidad Nacional de Colombia, Delabra-Salinas María Magdalena ,   Universidad Autónoma de Coahuila
Published: May 2024

This study aimed to create a genetic information processing technique for the problem of multiple alignment of genetic sequences in bioinformatics. The objective was to take advantage of the computer hardware's capabilities and analyze the results obtained regarding quality, processing time, and the number of evaluated functions. The methodology was based on developing a genetic algorithm in Java, which resulted in four different versions: Gp1, Gp2, Gp3 and Gp4 . A set of genetic sequences were processed, and the results were evaluated by analyzing numerical behavior profiles. The research found that algorithms that maintained diversity in the population produced better quality solutions, and parallel processing reduced processing time. It was observed that the time required to perform the process decreased, according to the generated performance profile. The study concluded that conventional computer equipment can produce excellent results when processing genetic information if algorithms are optimized to exploit hardware resources. The computational effort of the hardware used is directly related to the number of evaluated functions. Additionally, the comparison method based on the determination of the performance profile is highlighted as a strategy for comparing the algorithm results in different metrics of interest, which can guide the development of more efficient genetic information processing techniques.
The importance of removing interference caused by Darzalex® (daratumumab) in pre-transfusion testing
Authors: Dilberović Admir , Kola Lidija , Kola Ivan
Published: May 2024

Introduction: Multiple myeloma (MM) is a hematologic malignacy characterized by the uncontrolled proliferation of abnormal plasma cells in the bone marrow. Darzalex® (daratumumab) has emerged as a highly effective therapeutic agent for MM, offering an additional treatment option for patients who have developed resistance to other therapies. However, the use of Darzalex® poses challenges in pre-transfusion testing due to its strong binding affinity of the monoclonal anti-CD38 antibody to CD38 protein, resulting in panreactivity with test erythrocytes and complicating the detection of erythrocyte alloantibodies. The objective of this case report is to outline the procedures, significance, and methodologies for mitigating this interference using the DaraEx® reagent.
Case Report: We present the cases of three patients diagnosed with MM and treated with Darzalex® at our institution in 2023. Following the administration of Darzalex®, all three patients exhibited positive results on indirect antiglobulin tests (IAT). Cross-matching tests conducted with red blood cell concentrates also yielded positive results, with strengths ranging from 2+ to 3+. To eliminate interference, we used a specific DaraEx® reagent that utilizes Fab fragments of anti-CD38 to mitigate interference by masking CD38 on the cell surface. Subsequent application of this reagent resulted in negative IAT results for all three patients. However, one patient still displayed a weakly positive cross-matching test (<1+), suggesting that complete elimination of interference may not always be achievable with the DaraEx® method.
Conclusion: Despite the availability of reliable methods such as dithiothreitol and the DaraEx® reagent for mitigating interference, complete success in eliminating interference remains elusive. This underscores the importance of implementing proactive measures to prevent interference. Patients undergoing Darzalex® therapy should undergo comprehensive immunohematological testing before medication administration. Given the increased need for blood transfusions in MM patients, ensuring the compatibility of blood products is essential for safe transfusion practices.
Nefritis por shunt, un diagnóstico para tener en cuenta en la población pediátrica. Reporte de caso
Authors:   Hospital Infantil Napoleón Franco Pareja, Guerrero-Tinoco Gustavo Adolfo , Mendoza-Borja Karolay ,   Universidad de Cartagena, Arteta-Molina Sebastian Andres ,   Universidad Libre de Barranquilla, Orozco-Ochoa Maria Daniela ,   Universidad Libre de Barranquilla, Jiménez-Rodelo Jairo ,   Universidad de Cartagena
Published: May 2024

La nefritis por shunt es una complicación poco común que ocurre en pacientes con derivaciones ventriculares infectadas. Esta se presenta con síntomas como hematuria, fiebre, hipertensión, hepatoesplenomegalia y, en algunos casos, puede asociarse a la erupción cutánea y al compromiso del sistema nervioso central. El diagnóstico a menudo puede estar retrasado debido a la sintomatología inespecífica, y el tratamiento consiste en antibioticoterapia y el retiro de la derivación ventricular. Se describe el caso de una paciente de siete años con rasgo falciforme, síndrome de Dandy-Walker y derivación ventriculoatrial (DVA), quien presentó cuadros febriles en repetidas veces, anemia grave, hematuria microscópica persistente y lesión renal aguda. Es importante reconocer oportunamente la presentación clínica de esta complicación para lograr mejores resultados renales.
Applying OMG Essence with Bayesian Network to Software Project Management
Authors:   Tomsk State University, Tomsk, 634050, Russian Federation, Zmeev D. O. , Zmeev O. A. ,   Tomsk State University, Tomsk, 634050, Russian Federation, Ivanova L. S. ,   Tomsk State University, Tomsk, 634050, Russian Federation
Published: May 2024

There is little amount of applied math approaches which can be effectively and efficiently used in the modern software development projects. One of potential reasons is that most academic developers do not use software engineering foundations for designing and implementing math models of projects. We present an approach which uses OMG Essence standard and its applications and combines it with a Bayesian network, to achieve practically significant results for software project managers.
The Predicting the Significance of Patented Technologies based on Innovation Potential Metrics
Authors:   Volgograd State Technical University, Volgograd, 400005, Russian Federation, Korobkin D. M. , Rublev A. A. ,   Volgograd State Technical University, Volgograd, 400005, Russian Federation, Fomenkov S. А. ,   Volgograd State Technical University, Volgograd, 400005, Russian Federation
Published: May 2024

To ensure one of the key principles of the development of the state, namely, the achievement of technological sovereignty, it is necessary to build all spheres of life at a qualitatively new technological level, own their own innovative technologies. In modern sanctions realities, the development of enterprises in the Russian Federation cannot be carried out without coordination with partners from Russia, as well as from China, India and other friendly countries. The selection of potential partners can be carried out on the basis of the identified importance of their patented technological solutions. Further ranking of potential partners can be carried out on the basis of the identified importance of their patented technologies. At the same time, in this study it is proposed to use three criteria: the mass nature of the subject of the patented invention in the current period; the predicted mass nature of the subject (technology) in the future period; the popularity of the patent in the information field. The authors have developed a method for predicting the importance of patented technologies and its software implementation.
Concept of Processing and Interpretation of Spatiotemporal Vector Data
Authors:   Ufa University of Science and Technology, Ufa, 450078, Russian Federation, Orlov G. O. , Vorobeva G. R. ,   Ufa University of Science and Technology, Ufa, 450078, Russian Federation
Published: May 2024

The purpose of this work is to develop an approach to complex processing and interpretation of spatio-temporal vector data. In this regard, it is necessary to analyze existing methods for visualizing vector and tensor fields and organizing a database for their storage and develop a concept which contains the main advantages of these methods and allows one to interpret spatial data represented as a tensor. The developed concept proposes an approach to field visualization based on drawing superellipse glyphs at each point in space. Axes of glyphs correspond to the rank of the visualized tensor, and attribute values are expressed by varying the color gradient in its monochrome representation. The architecture of a web-based application, which implements the storage of spatial data in a hybrid DBMS, and interpretation of the necessary data upon request is also proposed. For the physical storage of tensor information, a hybrid relational-hierarchical model is proposed, in which the representation of direct spatial data and the corresponding metadata, including those characterizing the source of information, are separated. It is advisable to present the final result and intermediate data in GeoJSON format. This format is actually currently the standard for presenting geospatial data and is supported by almost all software platforms and libraries aimed at solving problems of this kind.
Method of Data Preprocessing on the Basis of Pulse Neural Network to Improve the Accuracy of Water Level Forecast on the Example of Ufa City of the Republic of Bashkortostan
Authors:   Financial University under the Government of the Russian Federation, Moscow, 109456, Russian Federation, Palchevsky E. V. , Antonov V. V. ,   Institute of Informatics, Mathematics and Robotics, Ufa University of Science and Technology, Ufa, 450008, Russian Federation, Makarova E. A. ,   Institute of Informatics, Mathematics and Robotics, Ufa University of Science and Technology, Ufa, 450008, Russian Federation, Kononov N. A. ,   Institute of Informatics, Mathematics and Robotics, Ufa University of Science and Technology, Ufa, 450008, Russian Federation, Voyakovskaya Ya. S. ,   Institute of Informatics, Mathematics and Robotics, Ufa University of Science and Technology, Ufa, 450008, Russian Federation
Published: May 2024

The developed method of data preprocessing based on impulse neural network is considered. The essence of this method is to improve the quality of the initial dataset by minimising data noise. The peculiarity is to improve the accuracy of the predicted values of the time series of water levels obtained at the output of the pulse neural network. Retrospective data were obtained from hydrological posts (river gauge) and automatic stations with the help of FSUE «Centre of Register and Cadastre» from 01.01.1997 to 30.06.2023. On the example of hydrological post 76289 (Ufa) the experiment on forecasting of water levels with the help of the developed system «Flood 2.0» was carried out. The experiment proves the efficiency of the data preprocessing method developed in this study to improve the accuracy of water level forecasts.
Forensic characteristics of damage caused by spherical striking elements of guided multiple-launch rocket system for multiple-launch rocket system type of ammunition
Authors: Kuzmina Vera A. , Leonov Sergey V. , Pinchuk Pavel V. , Blinov Nikolai N. , Vereskunov Alexey M.
Published: May 2024

BACKGROUND: Forensic aspects of blast injuries caused by the damaging elements of guided multiple-launch rocket system (GMLRS) type for MLRS ammunition are currently of particular interest because of the high frequency of occurrence and the lack of diagnostic criteria.
AIM: To study the morphological features of injuries caused by spherical impactors of GMLRS-type ammunition for MLRS in conjunction with electron microscopy and elemental analysis of impactors.
MATERIALS AND METHODS: The study was conducted using visual, metric methods, X-ray examination, and scanning electron microscopy (Hitachi FlexSem1000 II scanning electron microscope) with energy-dispersive X-ray analysis (Bruker Quantax 80 energy-dispersive X-ray spectrometer).
RESULTS: The morphological features of injuries caused by the damaging elements of GMLRS-type ammunition for MLRS were analyzed. Scanning electron microscopy and energy-dispersive analysis made it possible to identify the characteristic chemical composition of the damaging elements. X-ray examination of corpses revealed characteristic round shadows of metallic density.
CONCLUSION: The established morphological features of external and internal injuries caused by spherical damaging elements of GMLRS-type ammunition for MLRS, in combination with electron microscopy and elemental analysis, make it possible to establish, with high reliability, damage to the human body caused by the striking elements of the specified type of ammunition.
Evaluating Eye Injuries from Traffic Accidents in Turkey: American Medical Association Guideline vs. National Regulations
Authors: Turan Abdullah , Gamsız Bilgin Nursel , Kar Hakan
Published: May 2024

Objective: Traffic accidents are increasingly responsible for eye injuries, especially in developing countries. Through the analysis of impairment rates, this research aims to identify the strengths and weaknesses of the impairment assessment criteria.
Methods: Patients who applied to between January 1, 2015, and January 1, 2022 with eye injuries connected to traffic accidents had their sociodemographic and accident-related data scanned. Impairment rates were calculated individually for each case in accordance with the American Medical Association Guides to the Evaluation of Permanent Impairment (AMA guideline), the Regulation on Disability Assessment for Adults (Disability regulation), and The Regulation on Determination of Working Power and Loss of Profitability in Occupations [Social Security Institution (SSI) regulation].
Results: In our study, 67.1% of the 82 cases were male, with a mean age of 36.01. The cases exhibited the most common occurrences of corneal and nerve injuries. We observed a statistically significant difference in the medians of impairment rates calculated according to the AMA guidelines and the Disability and SSI regulations.
Conclusion: The calculation of impairment rates based on the SSI regulation for eye injuries revealed a constrained methodology, resulting in higher impairment rates compared to those determined by the AMA guideline and the Disability regulation. The Disability regulation and AMA guidelines were found to follow similar and detailed calculation methodologies. Within our country, we advocate for the adoption of a comprehensive guideline devoid of subjective interpretation for the determination of impairment rates in eye injuries resulting from traffic accidents, encompassing all conceivable eye-related diagnoses.
Yeni Kurulan Bir Adli Tıp Polikliniğine Başvuran Şiddet Mağduru Olguların Değerlendirilmesi
Authors: Özdemir Miraç
Published: May 2024

Amaç: Bu çalışmada, yeni kurulan bir Adli Tıp Polikliniğine ilk dokuz ayında başvuran şiddet mağduru olguların; sosyodemografik, tıbbi ve adli özelliklerinin irdelenerek, toplum sağlığı açısından ciddi bir sorun olan şiddetin önlenmesi ve adaletin daha etkin tesisi açısından uzmanların neler yapabileceğinin tartışılması amaçlanmıştır.
Yöntemler: Çalışmanın yapıldığı adli tıp birimine kurulduğu ilk gün olan 22.09.2022 tarihi ile 22.06.2023 tarihi arasında ayaktan, kolluk nezaretinde ve konsültasyon ile başvuran şiddet mağduru olguların adli raporları retrospektif incelenip olgular; şiddet türü, yaş, cinsiyet, başvuru zamanı, bulgular, konsültasyonlar ve sonuç açısından değerlendirilerek verilerin istatistiki analizi yapılmıştır.
Bulgular: Yüz yetmiş iki mağdurun %58,7’sinin erkek, %41,3’ünün kadın cinsiyette, %89’unun 18-65 yaş grubunda olduğu, %63’ünün kolluk tarafından muayeneye getirildiği, %97,6 ile en sık fiziksel şiddet tespit edildiği, uygulayıcının en sık tanınmayan kişiler olduğu, eylemin en sık açık alanda gerçekleştiği, olguların %64’ünün ilk 3 saat içinde muayeneye getirildiği, %74,4’ünün basit tıbbi müdahale ile giderilebilir yaraları bulunduğu, kadınların sıklıkla ev içinde ve eş-partnerleri tarafından, erkeklerin ise açık alan ve işyerinde tanıdıkları kişiler tarafından şiddete uğradığı, olguların en sık psikiyatri kliniğine konsülte edildiği belirlenmiştir.
Sonuç: Şiddet mağduru bireylerin cinsiyet, yaş gibi demografik özellikleri, maruz kaldığı şiddet türü ve hastaneye başvuru süresi gibi faktörler, şiddet olaylarının değerlendirilmesinde önemlidir. Bu veriler, şiddetin önlenmesi ve mağdurlara uygun tedavi ve destek sağlanması için de iyi bir kaynaktır. Sıklıkla ilk başvurunun olduğu acil servislerde görevli hekimlerinin adli olguların yönetiminde karşılaşabileceği sorunlarda hastanede var ise adli tıp uzmanından destek alınmasının, adli boyutun da tıbbi boyut gibi multidisipliner şekilde yürütülmesinin olgunun yönetimi açısından faydalı olabileceği unutulmamalıdır.