bluuebunny/crossref_metadata_2025 huggingface dataset:
Attentional control settings and visual working memory (preprint)
Authors: Plater Lindsay , Dube Blaire , Giammarco Maria , Donaldson Kirsten , Miller Krista , Al-Aidroos Naseem
Published: March 2021

In the present study, we examined whether visual working memory (VWM) can support attentional control settings (ACSs) by maintaining representations of the visual properties that should capture attention. Beyond enhancing capture by memory-matching stimuli, can VWM representations suppress capture by non-matching stimuli? In Experiments 1a/b, participants maintained a colour in VWM that changed every trial while completing a Posner cueing task with memory matching and memory non-matching colour cues. We replicated the conventional finding that the colour in VWM modulated distractor costs, indicating that the colour was represented in the active state. Yet, this colour had no effect on the capture of visual spatial attention measured via cueing effects, suggesting that merely remembering a colour in VWM did not define participants’ ACSs. When participants searched for the colour in VWM, it did support an ACS that eliminated cueing effects by non-matching colours (Experiment 2), though not if participants searched for two colours stored in VWM (Experiment 3). These findings demonstrate that one active representation in VWM can support ACSs, though active representation alone is insufficient. These findings also speak to the ongoing debate about the automaticity of attentional capture by contributing additional evidence that distractor costs and cueing effects are dissociable measures of attentional capture.
Development and Validation of a Novel Dementia Risk Score in the UK Biobank Cohort
Authors: Anaturk Melis , Patel Raihaan , Georgiopoulos Georgios , Newby Danielle , Topiwala Anya , de Lange Ann-Marie G. , Cole James Howard , Jansen Michelle G. , Ebmeier Klaus P. , Singh-Manoux Archana , Kivimäki Mika , Suri Sana
Published: March 2021

INTRODUCTION: Current prognostic models of dementia have had limited success in consistently identifying at-risk individuals. We aimed to develop and validate a novel dementia risk score (DRS) using the UK Biobank (UKB) cohort.METHODS: The UKB sample was randomly divided into a training (n=166,487, 80%) and test set (n=41,621, 20%). Logistic LASSO regression and standard logistic regression were used to develop the UKB-DRS.RESULTS: The score consisted of age, sex, education, apolipoprotein E4 genotype, a history of diabetes, stroke, and depression, and a family history of dementia. The UKB-DRS had good-to-strong discrimination accuracy in the UKB hold-out sample (AUC [95%CI]=0.79 [0.77, 0.82]) and in an external dataset (Whitehall II cohort, AUC [95%CI]=0.83 [0.79,0.87]). The UKB-DRS modestly but significantly outperformed four published risk scores (i.e., Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI), Cardiovascular Risk Factors, Aging, and Dementia score (CAIDE), Dementia Risk Score (DRS), and the Framingham Cardiovascular Risk Score across both test sets.CONCLUSION: The UKB-DRS represents a novel easy-to-use tool that could be used for routine care or targeted selection of at-risk middle-aged individuals into clinical trials.
European integration. Polish perspective
Authors: Grosse Tomasz , Paruch Waldemar , Czachór Zbigniew
Published: March 2021

An English-language version of the book Integracja europejska – polska perspektywa, published in 2018. It is a comprehensive elaboration of issues presenting a diagnosis of the current situation in Europe, a search for answers to the question about the future of European integration after the period of multiple crises at the beginning of the 21st century. The purpose of this publication is to show the perspective of Polish scholars on the future of the integration. It contains reflections on how the European discussion on the future of the European Union is perceived in Poland and how the Poles forecast Europe’s future.
DNA analysis of centuries-old linden trees using SSR-markers
Authors: Bilous S. Yu. , Prysiazhniuk L. M.
Published: March 2021

Centuries-old trees are not only natural monuments, but also objects of biological, genetic and ecological research. The most numerous group of perennial trees in Ukraine, along with members of the genus Quercus L. is Tilia L. Genetic analysis of perennial linden trees will assess genetic polymorphism between different members of the same species, search for reference communities, and create genetic maps within a species. DNA markers have become widespread among molecular DNA labeling methods, in particular SSR markers. To assess the polymorphism of ancients Tilia cordata L. in research were used 6 SSR markers (Tc5, Tc915, Tc920, Tc927, Tc937, Tc963). The main stages and results of PCR technique for genetic analysis of perennial linden trees using SSR markers and determination of genetic polymorphism between them are highlighted. Our own universal SSR-PCR test system for DNA identification of genotypes of perennial lindens has been developed. According to the results of SSR genotyping, DNA profiles were obtained for 6 samples of historically valuable and centuries-old trees of Tilia cordata L. aged 400-1000 years. Based on microsatellite analysis, genetic relationships and the level of genetic diversity of selected genotypes were assessed. As a result of PCR, alleles of the expected size were obtained. According to the calculated value of the half-morphology index of the locus (RIC), the most polymorphic marker Tc920 PIC was 0.72, the lowest value of genetic distances (1.73). According to the results of studies of 6 samples of small-leaved linden by molecular SSR markers, molecular genetic polymorphism was determined in all studied samples. The analysis showed that the sample was characterized by a low level of genetic polymorphism, which may be due to the use of a limited number of parental forms in the selection process or genetically related forms.
The German Mountain Troops and Their Opponents, 1943 to the Present
Authors: Stoltzfus Nathan
Published: March 2021

The most significant World War II battle between Germans and Italians outside of Italy was the September 1943 battle for the Greek island of Cephalonia, ending in the post-battle execution by German Mountain Troops of thousands of Italian soldiers. The recent clash between two German groups over what happened illustrates ongoing disputes about guilt and responsibility—how governments, historians, and civilians mobilize facts to write history. The Mountain Troops’ Veterans Association, which has influenced official German memory of the war, used the Cephalonia case to reassert the myth of Wehrmacht innocence, contrary to opinion-shaping Wehrmacht exhibits of the 1990s. In 2010, the federal government, backing a German judicial decision, reasserted the Wehrmacht Myth, despite opposition from Rome, Athens, and an international association of activists, as reports on right-wing extremism in the German police, judiciary, and military have become increasingly prevalent.
Analysis of requirements for modern spacecraft onboard network protocols
Authors: Olenev Valentin
Published: March 2021

Introduction: New technologies are replacing the onboard space networks based on bus topologies. One of these technologies is SpaceWire. New communication protocols are being developed, expanding SpaceWire functionality. The protocol developers should provide all the required technical characteristics for data transmission and processing. Purpose: Analysis of the existing requirements for communication protocols, and development of consolidated set of requirements that will take into account the modern requests of the space industry. Results: The analysis of the existing demands on communication protocols resulted in a set of consolidated requirements for the physical-network layers’ protocols and the transport layer protocols. The requirements cover the speed, latencies, transmission distance, transmitted information amount, fault detection functionality, time synchronization between the devices, quality of service, main user data types, and data transfer modes at the transport level. The existing SpaceWire protocols are defined as a special class of protocols, possessing unique characteristics. Practical relevance: The performed analysis can simplify the implementation of new onboard communication protocols and provide a required level of technique for new generation spacecraft.
PEMBELAJARAN MENULIS LAPORAN DENGAN TEKNIK KOOPERATIF TERPADU MEMBACA DAN MENULIS SMPN 1 GEBANG
Authors: Atin Sri
Published: March 2021

This research begins with the problem faced by the teacher, namely the lack of students' ability to understand the material. This study aims to improve the ability of grade IX students at SMPN 1 Gebang Cirebon Regency in understanding Indonesian subjects in the subject of "Technology" with the subject "Writing Reports" through the application of the Integrated Reading and Writing Cooperative Technique, so that learning Indonesian becomes more enjoyable and creates creativity. The method used was Classroom Action Research (PTK) which was carried out in class IX SMPN 1 Gebang Cirebon Regency. Activities carried out in two cycles of action. The results showed that the application of the Integrated Reading and Writing Cooperative Technique could improve students' understanding in learning Indonesian "Writing Report" in class IX of SMPN 1 Gebang Cirebon
PRODUK PEMBIAYAAN PADA LEMBAGA KEUANGAN SYARI’AH
Authors: Sufyan Sufyan
Published: March 2021

Abstrak

Artikel ini disusun untuk menyajikan produk pembiayaan pada lembaga keuangan syariah. Metode yang digunakan dalam penelitian ini berbasis pada data pustaka. Oleh karenanya, penelitian ini disebut penelitian kualitatif yang bersifat studi pustaka (library research) yang menggunakan literatur sebagai objek yang utama sebagai rujukan bahan kajian. Hasil penelitian menunjukkan bahwa terdapat tiga produk dan jasa yang ditawarkan dalam perbankan syariah. Ketiga produk dimaksud adalah produk penghimpun dana, produk penyaluran dana, dan produk jasa. Sementara untuk pembiayaan sendiri dapat dilakukan dengan prinsip bagi hasi, sewa, jual beli dan melalui akad pelengkap.
I IMPLIKASI KONSEP FIKIR DAN DZIKIR DALAM PENDIDIKAN ISLAM
Authors: Ismail Shalahudin
Published: March 2021

Penelitian ini bertujuan mengkaji mengenai implikasi konsep fikir dan dzikir dalam pendidikan Islam dengan menggunakan metode kepustakaan atau library research, yakni penelitian yang dilakukan melalui pengumpulan data atau karya tulis ilmiah dengan objek penelitian atau pengumpulan data bersifat kepustakaan. Hasil analisis menunjukkan bahwa pendidikan merupakan fitrah manusia yang harus dipenuhi. Karena sebagai fitrah, pendidikan harus senantiasa disesuaikan dengan fitrah kemanusiaan yang hakiki yakni menyangkut aspek material dan spiritual, aspek keilmuan sekaligus moral, aspek duniawi sekaligus ukhrawi. Pendidikan, diharapkan dapat merubah tingkah laku peserta didik, menambah pengetahuan peserta didik dengan menyalurkan atau mentrasnfer konsep ilmu pengetahuan serta mampu meningkatkan budi pekerti yang baik. Pendek kata, pendidikan Islam harus mampu mencetak pribadi Muslim ideal sebagai ‘abdullah sekaligus khalifatullah. Manusia mempunyai kewajiban untuk beribadah dan menjalankan apa yang diperintahkan Tuhan dan meninggalkan segala larangan-Nya. Manusia juga berkewajiban menjaga dan melestarikan kekayaan alam yang memang disediakan untuk kepentingan manusia.
STUDI KASUS SISTEM PENCARIAN DATA PENDUDUK MENGGUNAKAN METODE STUDY PRACTICE
Authors: Dandi Muhamad , Fernando Kinky , Hidayat Taufik
Published: March 2021

Sistem kependudukan yang selalu up to date sangat dibutuhkan untuk kegiatan pelayanan masyarakat di bidang  administrasi kependudukan pada suatu pemerintahan baik di daerah maupun pusat. Namun kondisi yang terjadi di masyarakat menunjukkan bahwa pelayanan masyarakat tersebut belum maksimal. Sistem kependudukan di Desa Patrol Lor saat ini masih manual sehingga kurang efisien dalam pengelolaan informasinya. Proses pelayanan pencarian data penduduk dari pihak desa masih dilakukan secara manual sehingga bisa dikatakan kurang efisien dalam melayani masyarakat. Pemanfaatan teknologi yang sudah ada dapat dilakukan dengan tujuan dapat menghemat waktu dan tenaga, oleh karena itu dibutuhkan sebuah sistem aplikasi kependudukan desa. Sistem aplikasi kependudukan di Desa Patol Lor ini dirancang untuk memudahkan pencarian NIK dengan menggunakn metode study practice dengan melalukan proses pretest dan posttest untuk mengetahui kebenaran hasil dari pemrosesan data serta melakukan analisa terhadap sistem tersebut. Sehingga dengan adanya sistem aplikasi kepedudukan desa ini dapat meningkatkan kualitas pelayanan bagi petugas desa dan dapat mempermudah petugas desa dalam mencari dan mengedit data kependudukan sehingga mempermudah melayani penduduk atau warga dalam mengontrol data penduduk dan menyediakan laporan kependudukan yang tepat dan akurat. Pada penelitian selanjutnya agar mengkombinasikan dengan metode laian akan system pencarian semakin cepat.
Foreign bodies’ inhalation, 38-year-experience Past, present and future
Authors: Hussen Waleed M.
Published: March 2021

Four decades of personal experience in dealing with the inhaled foreign body (FB)
Ways of presentations.
Methods of diagnosis.
Methods used for the successful removal the FBs using the rigid paediatric bronchoscope will be elucidated. 
The changing patterns of the types of FB during these years will be emphasized.
Majority of these incidents of inhaled FBs are preventable.
Predictors and Conversion Rate of Clinically Isolated Syndrome to Clinically Definite Multiple Sclerosis: A Follow-up Study in Patients Living in the Southern Part of Iran
Authors:   Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Izadi Sadegh , Ahmadi Meysam ,   Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran, Poursadeghfard Maryam ,   Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Published: March 2021

Background: Clinical course of Clinically Isolated Syndrome (CIS) is variable, and identifying patients who will eventually develop Multiple Sclerosis (MS) is essential. Objectives: To assess the conversion rate of CIS to Clinically Definite Multiple Sclerosis (CDMS) and its predictors in southern Iran. Materials & Methods: A total of 143 CIS patients registered to Fars Multiple Sclerosis Society (FMSS) were enrolled in the study from 2006 until 2012, and all of them were followed for 5 years. Also, their demographic and MRI data were recorded. The obtained data were analyzed by univariate and multivariable Cox regression models in SPSS v. 17. P<0.05 was considered statistically significant. Results: About 26.6% of patients progressed to MS after a mean duration of 3.4±1.1 years. The conversion rate was 27.6% in patients presented with optic neuritis, and 25.6% in patients presented with spinal cord problems. Although it was not statistically significant (P=0.23), the mean age of the patients who converted to MS was lower at the onset of the presentation (27.6 vs. 29.4 years). In patients who had 3 or more MRI lesions, the conversion rate was 49.2%; however, it was only 9.8% in subjects who had fewer than 3 lesions (OR=8.95, 95% CI=3.69–21.7, P <0.001). Women had higher conversion rate though it was not statistically significant (OR=2.09, 95% CI=0.57–7.64, P=0.26). Conclusion: Our results supported this supposition that the number of MRI lesions at baseline can be used as a predictor of CIS conversion to MS.
Reliability and Validity of the Persian Version Emotional Self-efficacy Scale for Young Adolescents
Authors:   Department of Motor Behavior, Faculty of Physical Education & Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran., Mohammadi Zahra , Meshkati Zohreh ,   Department of Motor Behavior, Faculty of Physical Education & Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
Published: March 2021

Background: The present research aimed at determining the reliability and validity of the Persian version of the Emotional Self-Efficiency Scale (ESES) for adolescents of Isfahan city. This study was conducted using a developmental research method. The statistical population consisted of all the first-grade high school students of Isfahan city in 2018 (n=59396). Methods: A total number of 280 students (160 girls and 120 boys, mean±SD age of 12.98±1.14) were selected using a stratified random sampling method, and completed ESES for adolescents (2015), as well as Self-Efficacy Questionnaire for Children (2001). Results: An Exploratory Factor Analysis (EFA) revealed the four-factor structure of ESES. A Confirmatory Factor Analysis (CFA) also confirmed the fit of the four-factor structure of the scale. The results of the within-group correlation coefficient were obtained to investigate the acceptable test-retest reliability. The results of the correlation between the above-mentioned scale and SEQ-C instrument was also significant (P<0.05). Moreover, ESES and its dimensions had proper reliability over time. The reliability obtained by Cronbach’s alpha for all four dimensions of the questionnaire, given the number of items, was higher than 0.5 for each dimension and higher than 0.7 for the whole scale, which was acceptable. Conclusion: These findings indicate the acceptable validity and reliability of ESES for Isfahan’s adolescents, and its validity and reliability should be investigated in broader research on Iranian children and adolescents.
Determinants of Subjective Well-being: Do we Really Know What Makes People Happy? A Study on Rasht Metropolis, North of Iran
Authors:   Department of Economic Development and Planning, Faculty of Management and Economics, Tarbiat Modares University, Tehran, Iran., Kaveh Sepideh , Assari Arani Abbas ,   Department of Economic Development and Planning, Faculty of Management and Economics, Tarbiat Modares University, Tehran, Iran., Faraji Dizaji Sajjad ,   Department of Economic Development and Planning, Faculty of Management and Economics, Tarbiat Modares University, Tehran, Iran., Hoseini Seyed Hasan ,   Department of Sociology, Faculty of Social Science, University of Tehran, Tehran, Iran
Published: March 2021

Background: Background: Recently, along with traditional economic indicators, policymakers are increasingly dealing with Subjective Well-Being (SWB) as an evaluation criterion of their performance and as an index for the population’s psychology health. This was done to define different determinants of SWB with a focus on some specific aspects of the living area. Also, this article investigateed the effect of urban and outskirts area on SWB. Method: This study is a cross-sectional study based on a structured interview and the samples (219 people ) were selected by a two-stage cluster sampling method in 2018 in Rasht city, a metropolis in Iran. In designing the local questionnaire, Gallup’s Global Emotions questionnaire has been used. Two main contributions of this study are defining culturized and proper indices for measuring SWB, and the financial status of people while Iranian people used to understate their real income. Data analysis was conducted using STATA 14.2 applying Descriptive statistics, Correlation study, Ordered Probit regression Method. Results: Results show that improving the socio-economic status of people improve SWB. Having financial satisfaction, satisfaction with leaving area, being tenure, and living in more spacious residency have positive effects on SWB. Also, the city dwellers were found to have higher SWB (5.23 out of 7) than outskirt dwellers (4.9 out of 7) while keeping the other factors to be constant. They reported the same differences in positive feelings and negative feelings indices. Conclusion: The welfare policies should be revised to improve the financial status of all people, and increase the access to urban facilities for outskirts’ dwellers.Determinants of Subjective Well-being: Do we Really Know What Makes People Happy? A Study on Rasht Metropolis, North of Iran
Capabilities and Requirements of the Elderly Remote Health Monitoring
Authors:   Department of Health Information Technology, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran., Shamsabadi Ahmad Reza , Delbari Ahmad ,   Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran., Safari Ameneh ,   Department of Health Information Technology, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran., Bahador Fatemeh ,   Department of Health Information Technology, School of Ferdows Paramedical, Birjand University of Medical Science, Birjand, Iran., Mehraeen Esmaeil ,   Department of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, Iran.
Published: March 2021

Objectives: Telehealth management systems for elderly people should have the features, capabilities, and infrastructure that meet home care managementchr('39')s diverse needs. Since there is no valid and reliable questionnaire to determine these requirements, this studychr('39')s primary purpose was to determine a telehealth monitoring systemchr('39')s requirements for the elderly and present it as a valid and reliable questionnaire. Methods & Materials: This study was descriptive-analytical and performed in 2019. The items for the Questionnaire were obtained from a systematic review study. To review, the selected keywords such as elderly, home care, telecare, telehealth, and information technology from 2013 to October 2019 were searched on selected databases. Results: Based on the studychr('39')s findings, the parameters, and requirements of a telehealth monitoring system for the elderly were identified in 97 items. Furthermore, the first 31 items of the questionnaire were removed due to low validity and reliability. In the next phase, the final questionnaire with 66 items, content validity ratio of 99%, Cronbachchr('39')s alpha coefficient (0.9) and desirable correlation coefficient (r=0.85, p<0.05) were designed. Conclusion: In this study, the requirements of a telehealth monitoring system for the elderly were determined, and a valid and reliable questionnaire was developed using these requirements. The questionnaire was designed in five parts: applications, functional requirements, non-functional requirements, tools, and communication infrastructure. Health care system designers may use the study results to determine the applications and requirements of elderly health monitoring systems.
Психологія особистості
Authors: Курова Анастасія Володимирівна
Published: March 2021

Навчально-методичний посібник з курсу «Психологія особистості» розроблено відповідно до навчального плану і складається з навчальної програми курсу, питань на практичні заняття, питання для підготовки до іспиту, завдань для самостійної роботи, списку рекомендованої літератури. Дисципліна «Психологія особистості» ознайомить здобувачів вищої освіти з основними підходами, теоретичними концепціями, щодо сутності і структури особистості, допоможе отримати практичні уміння з метою ефективного їх застосування в практичній діяльності на роботі в соціальних службах, у сфері освіти або у силових правоохоронних органах, що сприяє формуванню професійної самосвідомості щодо використання психологічних знань у майбутній професії. Матеріали призначені для студентів факультету психології, політології та соціології Національного університету «Одеська юридична академія», які навчаються за спеціальностями «соціологія», «психологія» та «політологія».
Análisis ambiental debido a la transición energética de la cascarilla de café: caso de estudio municipio de Villanueva, La Guajira.
Authors: Torres Daniela , Bastidas Marlon
Published: March 2021

Se analizó las propiedades de la cascarilla de café como fuente sustentable de biomasa en el municipio de Villanueva, La Guajira teniendo en cuenta que es uno de los principales productos cultivados en la región. Esta revisión se realizó mediante fuentes bibliográficas enfocadas en las temáticas de la cascarilla de café, el impacto ambiental generado por las cascarillas y las diferentes metodologías empleadas en la transición energética de este residuo con la finalidad del establecimiento de datos en donde se emplee este proceso para que generare valor agregado a un residuo que pasa a ser producto final, de manera que se vayan disminuyendo los impactos ambientales negativos e impulsando el adecuado manejo, aprovechamiento y disposición del residuo sólido. El estudio demostró que la cascarilla de café es una fuente primordial de biomasa energética por lo que se concluye que es una alternativa sostenible de alto poder calorífico y que puede ser empleada por su eficiencia energética como una estrategia en la disminución potencial de los efectos negativos en los recursos naturales impactados.
The Increasing Risk of Dementia in Psoriasis: A Systematic Review and Meta-Analysis
Authors: Chaiyabutr Chayada , Silpa-archa Narumol , Wongpraparut Chanisada , Chularojanamontri Leena
Published: March 2021

Objective: To systemically summarize and meta-analyze the risk of dementia in psoriasis patients.
Methods: A systematic review was performed in two databases (EMBASE and MEDLINE). The eligible studies had to be a cohort study or a cross-sectional study that compared either the prevalence or incidence of dementia in patients with psoriasis, versus individuals without psoriasis.
Results: Of 791 retrieved articles, seven studies met the inclusion criteria and were included into the meta-analysis. The risk of incident and prevalent dementia were significantly higher in patients with psoriasis, with a pooled risk ratio of 1.16 (95% CI: 1.02-1.33; I2 96%) and 1.36 (95% CI: 1.07-1.72; I2 10%), respectively.
Conclusions: This study revealed a slight increase in both the incidence and prevalence of dementia in psoriasis patients. However, dermatologists should carefully observe and periodically screen psoriasis patients for this comorbidity, especially among those who have symptoms and signs of cognitive impairment.
Pilot Study of the Efficacy and Safety of Nail Gel Containing Artemisia abrotanum Extract and Glycerin in the Treatment of Nail Plate Surface Abnormality
Authors: Varothai Supenya , Bunyaratavej Sumanas , Leeyaphan Charussri , Phaitoonwattanakij Sutasinee , Winayanuwattikun Waranaree , Munprom Kanyalak
Published: March 2021

Background: Nail gels are utilized for the treatment of nails for nail plate surface abnormalities. However, the objective measurement of nail gel treatment is limited.
Objective: This study investigated the efficacy and safety of a nail gel containing glycerin and Artemisia abrotanum extract in treating nail plate surface abnormalities.
Material and Methods: All nails were evaluated with a Visiometer® system and by transonychial water loss (TOWL) at baseline, and at the 2nd and 8th weeks of treatment.
Results: In total, 19 patients with a mean age of 50.6 years old were enrolled and 50 nails were studied. Sixty percent of the patients showed significant clinical improvement, as determined by the total agreement between two treatment-blinded dermatologists. Regarding the Visiometer®, a significant reduction in the SER value (roughness) of the nail plates was found at the 2nd week, while at the 8th week, the surface and volume values had significantly decreased from baseline and also from the values at the 2nd week. There was a significant improvement in the Rku (smoothness) value at the 8th week compared to baseline. The mean TOWL at the 2nd and 8th weeks were statistically decreased from baseline. No side effects were detected.
Conclusions: This nail gel containing Artemisia abrotanum extract provided benefits in restoring hydration and improving the nail barrier in patients with nail surface abnormalities.
The Effect of the Herringbone Technique on Reading Comprehension
Authors: Amumpuni Rengganis Siwi
Published: March 2021

The purpose of this research is to know the effect of the Herringbone technique on students' reading comprehension. A quasi-experimental was used in this research and the sample was 20 students of Guidance and conselling department . Test was used in this research to collect the data and  the data was analyzed by paired sample T-test by using SPSS. The result of this research, there was a significant effect of the herringbone to the students 'reading comprehension. It can be seen from the value of the t-test that the score was  higher  than t- table (11.212 > 2.086).  Therefore, it can be stated that the there is a significant effect of Heringbone technique on students’ reading comprehension.
Analisis Pengaruh Indikator Persepsi dan Partisipasi Layanan Bantuan Akademik Terhadap Prestasi Akademik Mahasiswa Peserta Tutorial di UPBJJ-UT Bengkulu
Authors: Mikaresti Pamela , Nurmalia Ana , Kristanti Dwi
Published: March 2021

This study aimed to analyze the effect of indicators of student perceptions and participation in academic service assistance on student academic achievement at UPBJJ-UT Bengkulu. The research used descriptive method with a quantitative approach. sampling used the Slovin method with a total sample of 362 respondents. The research instrument used was questionnaire. The data analysis technique useed multiple linear regression which was further discussed descriptively. The results of the study showed the independent variables such as X1, X2, X3, X6, X9, X13, X20, X24, partially had a significant effect on the dependent variable (GPA). Other independent variables (X4, X5, X7, X8, X10, X11, X12, X14, X15, X16, X17, X18, X21, X22, X23) partially had no significant effect on the dependent variable (Student Achievement Index).
Pelatihan Apoteker Cilik dan DaGuSiBu bagi Siswa SDN Losari di Singosari, Kabupaten Malang
Authors: Atmadani Rizka Novia , Hidayati Ika Ratna
Published: March 2021

The purpose of this service activity is to introducing medicine from early age in order to introduce pharmacists and medicine to elementary school students. The lack of knowledge about medicines in the community begins with the provision of knowledge from an early age to elementary school students because they will later become adolescents and reduce drug abuse in the community as frequently happens to high school students or college students. The method of these activities is carried out by means of online learning using several platforms, including: class whatsapp group, google form, and youtube link. Before being given the material, a pretest and posttest was admitted at the beginning and end of the activity. There are two materials provided, first, introducing Pharmacist Profession and education for DaGuSiBu. The participants of this activity were elementary students of grade 4,5 and 6 SDN Losari. In addition, this service is expected to motivate students to have awareness and be able to supervise other classmates for practicing medicines properly.The results was found that the students received education related to the Pharmacist Profession and understood about DaGuSiBu (properly get, use, save, and throw away the medicines) with the results of the average pretest and posttest scores about Pharmacist of 7.08 and 7.23 respectively, meanwhile DaGuSiBu education was 6.20 for pretest and postest 7.18. So it can be concluded that there was increasing points in knowledge after being given education.
THE INFLUENCE OF GROUP INVESTIGATION TYPE COOPERATIVE LEARNING MODEL ON STUDENT LEARNING OUTCOMES IN THE THEMES OF OUR FRIENDS 'ENVIRONMENTAL CLASS V SD NEGERI 101859 RAMBAI 2019/2020 LEARNING YEAR
Authors: Tarigan Feronika , Lumbangaol Rumiris , Simarmata Ester , Silaban Patri Janson
Published: March 2021

This research method is a descriptive method which is carried out in one class, namely the experimental class. The instrument used to collect data was multiple choice questions. Hypothesis testing is done using the "t" test. The results of statistical calculations show that the learning outcomes using the Group Investigation model are in the very good category with an average value of 85.8, while the learning outcomes without using the Group Investigation model are in the moderate category of 67.02. Furthermore, testing the hypothesis shows tcount is 9.385 then consulted with t table at the significant level α = 0.05. Therefore the tcount obtained is greater than ttable, namely 9.385> 0.000, it is proven that the value hypothesis or (Ho) is rejected and the alternative hypothesis (Ha) is accepted. So, it can be concluded that the Group Investigation model has a significant effect on the learning outcomes of grade V SD Negeri 101859 Rambai for the 2019/2020 academic year. Thus, this learning model is appropriate to use in the learning process, especially in influencing better learning outcomes.
FETAL ULTRASOUND AND NEONATAL DIAGNOSIS OF CONGENITAL HEART DEFECTS
Authors: Sima Romina
Published: March 2021

The congenital heart defect is one of the major causes of neonatal and pediatric mortality. A retrospective study of all the patients with singleton pregnancies, admitted in our hospital between 2010-2012 was performed. The data collected included information referring to the age of the patients, the gestational age, the cardiac diagnosis, the extracardiac anomalies, the prenatal and postnatal management and evolution. Out of 7,195 patients, 23 living newborns had CHDs (congenital heart defects). The mean gestational age was 34.12 weeks (range 30-39 weeks). We recorded VSD (ventricular septal defect) in 47.8% newborns, ASD (atrial septal defect) in 26.1% cases, TGA (transposition of great arteries) in 8.7% cases, coarctation of the aortic artery (COA) in 4.3% cases, TOF (tetralogy of Fallot) in 8.7% cases and HLHS (hypoplastic left heart syndrome) in 4.3% cases. The ultrasound findings in utero were VSD (30.4%), ASD (39.1%), TGA (4.3%), coarctation of the aortic artery (4.3%), TOF (4.3%) and HLHS (4.3%). In our study there was a strong correlation between the antenatal ultrasound findings and the neonatal diagnosis.
THE ROLE OF CECOSTOMY IN THE SURGICAL PATHOLOGY OF THE COLON
Authors: Mihai Ana Maria , Alecu M. , Simion L. , Straja N. D.
Published: March 2021

In spite of a correct surgical technique, colon interventions can lead to complications of the fistula, sometimes real abdominal dramas, worsening the prognosis of these patients and hardening the surgical technique. We present the evolution of a patient initially treated endoscopically for a sigmoid polyp. The histopathological examination of the biopsy confirmed its malignant character, with invasion of the pedicle, for which reason the endoscopic polypectomy is considered insufficient from an oncological point of view and a colonic resection is advisable. In the postoperative evolution of the patient there appear complications through the occurrence of an anastomotic fistula and peritonitis, whose presence leads to the necessity of performing a terminal colostomy which permits the cessation of the inflammatory syndrome. The further reinstatement of transit is done by means of an “a minima” cecostomy, thus reducing the clinical impact in case of other complications of the fistula. The following elements were analyzed: the patient’s history, associated diseases, fistula-related risk factors, biochemical, imaging and clinical samples, elements related to the surgical technique and the entire postoperative evolution of the patient. This paper stands as an argument in supporting the advantages of “a minima” cesostomy in case of colon surgery, proving how a technical artifice which is minimally invasive for the patient and easy to achieve may become very useful in solving or even preventing some severe complications arising on the background of a simple pathology.
ARE TUMORAL MARKERS PREDICTIVE FACTORS FOR MOLECULAR SUBTYPES IN BREAST CANCER?
Authors: Munteanu V. , Radu Georgiana , Cirstoiu Monica
Published: March 2021

Breast cancer kills more women annually than any other type of neoplasm. Even though he has shown a particular interest in the medical body since ancient times, the very heterogeneous nature of the tumors and their versatility have made it difficult to find a diagnostic and therapeutic consensus that fully characterizes this pathology and describes its evolution. Immunohistochemical methods manage to outline a gene-molecular profile depending on the biomarkers expressed by each tumor. Correlations between clinical aspects and molecular characteristics of tumors are of particular importance in the management of such a case. The study examined the impact of breast cancer molecular subtypes on therapeutic management for a group of 438 patients treated on the Oncology Department of the Bucharest University Emergency Hospital during 2007-2017.
EARLY OUTCOME OF PANCREATICODUODENECTOMY IN SEPTUAGENARIANS AND OCTOGENARIANS IN NEPAL
Authors: Ghimire Roshan , Maharjan Dhiresh , Thapa Prabin Bikram
Published: March 2021

Elderly population is growing because of increasing life expectancy. Decision-making for major surgery like pancreaticoduodenectomy in this group is challenging. Therefore, we evaluated the feasibility of this procedure by comparing perioperative outcomes in Septuagenarians and Octogenarians patients. From August 2017 to December 2019, 18 consecutive patients who underwent pancreaticoduodenectomy were enrolled. These patients were divided into two groups (group1 – septuagenarians and group 2 – octogenarians). A comparative study between two groups was done regarding perioperative outcome and early complications. 18 patients were enrolled, 10 patients (55.6%) were septuagenarians (70-80 years) and 8 (44.4%) patients were Octogenarians (>80 years). There was no significant difference in the rate of surgical and medical complications between the two groups. Furthermore, there were no significant differences in risk factors, blood loss and operating time between the groups. Overall mortality in the study is 5.5%. Pancreaticoduodenectomy is feasible treatment option in septuagenarians and octogenarians with the help of multidisciplinary approach. Age alone should not be considered as decision maker for pancreaticoduodenectomy.
FAKTOR PENYEBAB TERJADINYA INTERFERENSI BAHASA INDONESIA TUTURAN MAHASISWA THAILAND PADA PEMBELAJARAN PPL DASAR DI UNIVERSITAS HASYIM ASY’ARI
Authors: Ulfa Siti Mariana , M. Basir Udjang Pairin , Prihatin Yulianah
Published: March 2021

Penelitian ini bertujuan untuk mengetahui faktor penyebab terjadinya interferensi Bahasa Indonesiayang terjadi pada mahasiswa Thailand saat praktik mata kuliah PPL di Universitas Hasyim Asy’ari.Metode penelitian ini menggunakan metode kualitatif dengan teknik pengumpulan data menggunakanteknik observasi, teknik merekam audio visual dengan menggunakan CCTV di ruang praktik, dan teknikmencatat. Untuk mendapatkan keabsahan data peneliti menggunakan triangulasi data, peningkatanpenekunan dan pemeriksaan teman sejawat melalui diskusi. Adapun proses analisis datanya yaitupengumpulan data, reduksi data, penyajian data, dan simpulan. Kebanyakan pada tuturan mahasiswaThailand sering terjadi interferensi pada sistem fonologi, dimana mereka masih terbawa oleh bahasapertama atau bahasa ibu (B1) yaitu bahasa Melayu. Interferensi pada sistem morfologi serta pada sistemsintaksis dapat terjadi karena mereka kurang memahami kosa kata dan susunan kalimat pada bahasaIndonesia yang baik dan benar.
EFFECT OF THE USE OF FRACTIONAL MEDIA PUZZLES IN GRADE III STUDENTS AT SDN PUCANGSIMO I
Authors: Rusdiana Rina , Basir Udjang Pairin M. , Nuruddin Muhammad
Published: March 2021

The study was backed by teachers who did not use the learning media while learning to teach and students felt difficulties in remembering and understanding fractional matter so that many students gained value under the embassy. Based on the background, the research aims to describe the influence of the use of media puzzles on student learning outcomes. This method of research is Pre-Experimental Design with One Group Of Pre-Test Post-Test which only involve one class. The purpose of this research is to learn the students ' learning outcomes before and after using the media puzzle in grade III students at SDN Pucangsimo 1. The samples in this study were grade III students numbering 49 children. This study was conducted for two meetings with a 1-week time interval. The results showed that in pretests activities (without using media) There are 30 students in the category of incomplete, there are 10 students who are in the category completed or reach the value of the KKM and there are 9 students who value above the KKM. As for the average student learning results when Pretests reaches 68 in the classical has not fulfilled the KKM, while in post-test activities There are 35 students who obtained a value above the KKM with an average of 83. The influence of learning the fractional material mathematics of grade III students at SDN Pucangsimo 1 shows that there is a significance difference of 0.00 smaller than the significance of 0.05 (0.000 < 0.05), then the hypothesis (H1) in this study was declared acceptable. This means that the variable use of media puzzles affects students ' learning outcomes before and after using the media puzzle in the learning process.
A Machine Learning Enhanced Mechanistic Simulation Framework for Functional Deficit Prediction in TBI
Authors: Schroder Anna , Lawrence Tim , Voets Natalie , Garcia-Gonzalez Daniel , Jones Mike , Peña Jose-Maria , Jerusalem Antoine
Published: March 2021

Resting state functional magnetic resonance imaging (rsfMRI), and the underlying brain networks identified with it, have recently appeared as a promising avenue for the evaluation of functional deficits without the need for active patient participation. We hypothesize here that such alteration can be inferred from tissue damage within the network. From an engineering perspective, the numerical prediction of tissue mechanical damage following an impact remains computationally expensive. To this end, we propose a numerical framework aimed at predicting resting state network disruption for an arbitrary head impact, as described by the head velocity, location and angle of impact, and impactor shape. The proposed method uses a library of precalculated cases leveraged by a machine learning layer for efficient and quick prediction. The accuracy of the machine learning layer is illustrated with a dummy fall case, where the machine learning prediction is shown to closely match the full simulation results. The resulting framework is finally tested against the rsfMRI data of nine TBI patients scanned within 24 h of injury, for which paramedical information was used to reconstruct in silico the accident. While more clinical data are required for full validation, this approach opens the door to (i) on-the-fly prediction of rsfMRI alterations, readily measurable on clinical premises from paramedical data, and (ii) reverse-engineered accident reconstruction through rsfMRI measurements.
Engineering of Aeromonas caviae Polyhydroxyalkanoate Synthase Through Site-Directed Mutagenesis for Enhanced Polymerization of the 3-Hydroxyhexanoate Unit
Authors: Harada Ken , Kobayashi Shingo , Oshima Kanji , Yoshida Shinichi , Tsuge Takeharu , Sato Shunsuke
Published: March 2021

Polyhydroxyalkanoate (PHA) synthase is an enzyme that polymerizes the acyl group of hydroxyacyl-coenzyme A (CoA) substrates. Aeromonas caviae PHA synthase (PhaCAc) is an important biocatalyst for the synthesis of a useful PHA copolymer, poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)]. Previously, a PhaCAc mutant with double mutations in asparagine 149 (replaced by serine [N149S]) and aspartate 171 (replaced by glycine [D171G]) was generated to synthesize a 3HHx-rich P(3HB-co-3HHx) and was named PhaCAc NSDG. In this study, to further increase the 3HHx fraction in biosynthesized PHA, PhaCAc was engineered based on the three-dimensional structural information of PHA synthases. First, a homology model of PhaCAc was built to target the residues for site-directed mutagenesis. Three residues, namely tyrosine 318 (Y318), serine 389 (S389), and leucine 436 (L436), were predicted to be involved in substrate recognition by PhaCAc. These PhaCAc NSDG residues were replaced with other amino acids, and the resulting triple mutants were expressed in the engineered strain of Ralstonia eutropha for application in PHA biosynthesis from palm kernel oil. The S389T mutation allowed the synthesis of P(3HB-co-3HHx) with an increased 3HHx fraction without a significant reduction in PHA yield. Thus, a new workhorse enzyme was successfully engineered for the biosynthesis of a higher 3HHx-fraction polymer.
Recent Progress in Solar-Induced Direct Biomass-to-Electricity Hybrid Fuel Cell Using Microalgae as Feedstocks
Authors: Peng Kun-Tao , Wang Xiang , Peng Gong , Yu Lin , Li Hong-Ye
Published: March 2021

Microalgae, as potential biodiesel feedstocks, have been widely reported to accumulate oil via genetic engineering techniques, or environmental stress regulation. Recently, the utilization of fuel cell technology to convert biomass into electricity has attracted much more attention due to its high efficiency, low pollution, low noise by microalgae as feedstocks. Normally, platinum and analogous noble metals as catalysts have been already demonstrated although they still exist lots of shortcomings. This mini review presents an overview of various fuel cell technologies with phosphomolybdic acid as catalysts for sustainable energy by using microalgae. Trends from literatures demonstrate that algal-based fuel cells could efficiently generate electricity, and concurrently produce high value-added products. This critical review can provide guiding suggestions for future study of algal-based energy conversion by fuel cell techniques.
Amyloid-Like Aggregation in Diseases and Biomaterials: Osmosis of Structural Information
Authors: Balasco Nicole , Diaferia Carlo , Morelli Giancarlo , Vitagliano Luigi , Accardo Antonella
Published: March 2021

The discovery that the polypeptide chain has a remarkable and intrinsic propensity to form amyloid-like aggregates endowed with an extraordinary stability is one of the most relevant breakthroughs of the last decades in both protein/peptide chemistry and structural biology. This observation has fundamental implications, as the formation of these assemblies is systematically associated with the insurgence of severe neurodegenerative diseases. Although the ability of proteins to form aggregates rich in cross-β structure has been highlighted by recent studies of structural biology, the determination of the underlying atomic models has required immense efforts and inventiveness. Interestingly, the progressive molecular and structural characterization of these assemblies has opened new perspectives in apparently unrelated fields. Indeed, the self-assembling through the cross-β structure has been exploited to generate innovative biomaterials endowed with promising mechanical and spectroscopic properties. Therefore, this structural motif has become the fil rouge connecting these diversified research areas. In the present review, we report a chronological recapitulation, also performing a survey of the structural content of the Protein Data Bank, of the milestones achieved over the years in the characterization of cross-β assemblies involved in the insurgence of neurodegenerative diseases. A particular emphasis is given to the very recent successful elucidation of amyloid-like aggregates characterized by remarkable molecular and structural complexities. We also review the state of the art of the structural characterization of cross-β based biomaterials by highlighting the benefits of the osmosis of information between these two research areas. Finally, we underline the new promising perspectives that recent successful characterizations of disease-related amyloid-like assemblies can open in the biomaterial field.