bluuebunny/crossref_metadata_2025 huggingface dataset:
The linguistic expression of gender identity: Albania’s “sworn virgins”
Authors: Dickerson Carly
Published: February 2019

This article focuses on the linguistic aspects of the construction of masculine identities by theburrneshat(also known as “sworn virgins”) of northern Albania: biological females who have become “social men”. Unlike other “third genders” (Kulick, Don. 1999. Transgender and language: A review of the literature and suggestions for the future.GLQ: A Journal of Lesbian and Gay Studies5(4). 605622.), theburrneshatare motivated not by personal identity or sexual desire, but by the need to fulfill patriarchal roles within a traditional social code.Burrneshatdo not marry or engage in sexual relationships, and are thus seen as honorable and self-sacrificing (Young, Antonia. 2000.Women who become men: Albanian sworn virgins. Oxford & New York: Berg.). How doburrneshatconstruct and express their identity linguistically, and how do others engage with this identity? I examine the effects of social and linguistic factors on variation in the use of grammatical gender in the speech ofburrneshatand others in their communities. I find that choices in grammatical gender are linked to the speaker’s relationship toburrneshat, the grammatical context of the token, and whether the token is in oral or written language. An analysis of other gendered practices confirms language’s role in building masculine identities. Situated within a culture that embraces women becoming men, this study sheds light onto the linguistic practices used by speakers in the co-construction of gender.
Discourses of transnormativity in vloggers’ identity construction
Authors: Jones Lucy
Published: February 2019

This article investigates the construction of two transgender vlogger personas, providing insight into the prevalence of normative discourses which may be drawn on when constructing transgender identities. Many transgender people around the world rely on the internet as a source of information and guidance, with online video diaries (“vlogs”), in which young people record and chart their experiences of transition, playing a particularly important role. In this article, discourse from two popular transgender vloggers is critically analysed. It is found that the vloggers index identities which are broadly in line with what Lal Zimman terms the archetypal “true transsexual”, an ideological model of what it means to be “authentically” transgender. This corresponds with heteronormative, essentialist expectations of binary gender. The vloggers are shown to authenticate their own experiences by stating what is “typical” and positioning themselves as “experts”. Ultimately, it is argued that the version of transgender identity and experience that they put forward reproduces prevalent discourses of normative gender and sexuality.
Self-misgendering among multilingual transgender speakers
Authors: Simpson Lauren , Dewaele Jean-Marc
Published: February 2019

“Misgendering” is a term used broadly to mean referring to someone using the wrong gender. In the transgender context, it usually refers to cases where a transgender person is referred to using the gender assigned at birth, rather than according to gender presentation. Misgendering is sometimes a form of anti-trans aggression, but can also be accidental or otherwise unintended. “Self-misgendering”, where transgender speakers unintentionally misgender themselves, is apparently previously unstudied, seems mainly to occur in a foreign-language context, and may bear some similarity to language-interference effects observed in the study of multilinguals, a “first-gender effect” analogous to first-language effects. One may also hypothesise social gender bias, variable gender-identity, or similar factors. This article quantitatively surveys self-reported self-misgendering among multilingual transgender speakers to identify factors of correlation or causation. Using data and respondents’ comments from an online survey, it shows strong correlation between self-misgendering by full-time transgender speakers and (lack of) fluency in the language spoken, with no significant correlation to other linguistic or social gender-related factors. This suggests the self-misgendering phenomenon is primarily a fluency effect, independent of social or identity factors such as attitude to gender in language, attitude to being misgendered, or “default” masculine gender.
Crystal structure of N-(2-methylphenyl)(propan-2-yloxy)carbothioamide, C11H15NOS
Authors: Yeo Chien Ing , Tiekink Edward R.T.
Published: February 2019

C11H15NOS, monoclinic, P21/n (no. 14), a = 7.3979(4) Å, b = 8.5384(4) Å, c = 18.2771(10) Å, β = 90.999(3)°, V = 1154.32(10) Å3, Z = 4, R
gt(F) = 0.0409, wR
ref(F
2) = 0.1093, T = 100(2) K.
Studies on purification of 89Sr from irradiated yttria target by multi-column extraction chromatography using DtBuCH18-C-6/XAD-7 resin
Authors: Saha Debasish , Vithya Jayagopal , Kumar Ramalingam , Joseph Mathew
Published: February 2019

89Sr is being produced using yttria target via the nuclear reaction 89Y(n,p)89Sr in Fast Breeder Test Reactor (FBTR), Kalpakkam. The isotope 89Sr is a pure beta emitter with a half-life of 50.53 days which is useful mainly for bone pain palliation in patients with bone metastases. The existing method for processing the irradiated yttria target to obtain the pure 89Sr source involves separation of the bulk yttrium target by solvent extraction using TBP-HNO3 followed by purification of 89Sr source by cation exchange chromatography technique using Dowex resin. The study described here involves the selective extraction and purification of 89Sr by multi-column extraction chromatography technique using the Sr-specific crown ether, DtBuCH18C6 (CE) coated onto an XAD-7 resin matrix for superior separation and increased yield compared to single column technique. The 89Sr source thus purified from the irradiated yttria target is free from other radionuclidic impurities produced during the target irradiation i.e. 88Y, 65Zn, 139,141Ce, 154Eu and 160Tb.
Removal of U(VI) from aqueous solution using phosphate functionalized bacterial cellulose as efficient adsorbent
Authors: Zhuang Shuting , Wang Jianlong
Published: February 2019

In this study, phosphate functionalized bacterial cellulose with micro-fibrous structure was prepared, characterized and applied for U(VI) adsorption. The successful grafting of phosphoric functional groups was proved by the FTIR spectra and EDS analysis (P~4.15 wt%), and the porous structure was confirmed by SEM and BET analyses. Furthermore, the effect of initial pH, contact time, initial concentration, and temperature were studied. The as-prepared adsorbent showed a high adsorption capacity at wide pH range (4.0–8.0) and its maximum adsorption capacity was calculated to be 50.65 mg/g. This endothermic adsorption process conformed to the pseudo second-order kinetic model and the Elovich kinetic models and the Langmuir isothermal models. According to the FTIR and XPS analysis, an adsorption mechanism was tentatively proposed, mainly due to the interaction between U(VI) and phosphoric groups.
Advances in the applications of graphene adsorbents: from water treatment to soil remediation
Authors: Zhao Lianqin , Yang Sheng-Tao , Yilihamu Ailimire , Wu Deyi
Published: February 2019

Graphene, a novel carbon allotrope, is single-layered graphite with honeycomb lattice. Its unique structure endows graphene many outstanding physical/chemical properties and a large surface area, which are beneficial to its applications in many areas. The potential applications of graphene in pollution remediation are adsorption, membrane separation, catalysis, environmental analysis, and so on. The adsorption efficiency of graphene adsorbents largely depends on its surface area, porous structure, oxygen-containing groups and other functional groups, adsorption conditions, and also the properties of adsorbates. With appropriate modifications, graphene materials are mostly efficient adsorbents for organic pollutants (e.g. dyes, pesticides, and oils) and inorganic pollutants (e.g. metal ions, nonmetal ions, and gas). Since our first report of graphene adsorbents in 2010, plenty of studies have been dedicated to developing various graphene adsorbents and to evaluating their performance in treating contaminated water. Recently, there is a growing trend in graphene adsorbents that could be applied in soil remediation, where the situation is much more complicated than in aqueous systems. Herein, we review the design of graphene adsorbents for water treatment and analyze their potential in soil remediation. Several suggestions to accelerate the research on graphene-based soil remediation technology are proposed.
Synthesis of novel 1,2,3-triazole-substituted tomentosins
Authors: Zaki Mohamed , Oukhrib Abdelouahd , El Hakmaoui Ahmed , Hiebel Marie-Aude , Berteina-Raboin Sabine , Akssira Mohamed
Published: February 2019

A series of 1,2,3-triazole-containing tomentosin scaffolds was obtained from tomentosin1. The synthesis involved a Michael addition of trimethylsilylazide on theα-methylene-γ-lactone function of the natural sesquiterpene lactone1to give the diastereoisomers2and3, which were readily separated by column chromatography. These compounds underwent copper-catalyzed Huisgen 1,3-dipolar cycloaddition with various terminal alkynes to provide compounds4a–hand5a–hin good yields.
Morphology-Combined Gradient Boosting for Recognizing Targets in SAR Images
Authors: Bhardwaj Shubham , Lal Anisha M.
Published: February 2019

This article proposes a novel method for recognizing objects in synthetic aperture radar images. The target is initially detected using a proposed morphology-based segmentation process and is further confirmed by classifying the objects. The identified target after the proposed segmentation process is subjected to feature extraction using Zernike moments, which efficiently downsamples the features and makes them rotationally invariant. The features are classified using a tree-based method called gradient boosting. Gradient boosting, by far, has shown very promising results on various kinds of data sets. The main focus is to bring to light this kind of tree-based architecture for target recognition in satellite imagery as well as to propose a framework that reduces the overall time and improves the efficiency of the process. It outperforms the previous state-of-the-art methods for this data size. The proposed method is compared with existing techniques to measure and evaluate its performance.
Testing and Evaluation of Tensile and Impact Strength of Neem/Banyan Fiber-Reinforced Hybrid Composite
Authors: Thandavamoorthy Raja , Palanivel Anand
Published: February 2019

Natural fiber-reinforced hybrid composites are prime focus materials for numerous engineering applications. In this research work, chopped neem (Azadirachta indica) fibers and bidirectional banyan (Ficus benghalensis) woven fabric-reinforced epoxy hybrid composites were fabricated using the conventional hand lay-up technique. Two fibers, namely chopped neem fiber and woven banyan fiber, were stacked in three different sequences. The weight fraction of these two fibers was varied to quantify the strength of the hybrid composite. The mechanical properties, such as tensile, compression, and impact tests, were carried out to quantify the effect of the fiber weight fraction and the stacking sequence of fiber on the strength of the hybrid composite. The increase in 9 % woven banyan fiber weight fraction has a positive influence on the tensile and compressive strengths of the natural fiber-reinforced hybrid composites. Further, the stacking sequence of these two fibers has significant influence on the compressive strength of the hybrid composites. The impact energy absorption capacity of the hybrid composite is more significantly increased with an increase in the 9 % chopped neem fiber weight fraction than with an increase in the banyan fiber weight fraction. The scanning electron microscopy surface morphological analysis revealed the dominant mode of failure in the hybrid composites.
Negociación colectiva y técnica normativa en la tramitación parlamentaria de la Ley de Transparencia y Buen Gobierno de Galicia
Authors: Sarmiento Méndez Xosé Antón
Published: February 2019

Tras aludir a la situación de la transparencia en Galicia hasta 2016, se analizan los aspectos esenciales de la LGT que fueron objeto de negociación en el Parlamento de Galicia, de forma tal que se modificó el proyecto de ley enviado por el Gobierno. Es el caso de las obligaciones de publicidad activa, de los derechos de acceso o del control de dichas obligaciones. También hay ejemplos en la transición entre gobiernos o en las incompatibilidades y conflictos de intereses. Todo ello demuestra el relevante esfuerzo por llegar a ciertas transacciones y consensos en el tema de transparencia en la cámara gallega.
Random Chromosome Partitioning in the Polyploid BacteriumThermus thermophilusHB27
Authors: Li Haijuan
Published: February 2019

Little is known about chromosome segregation in polyploid prokaryotes. In this study, whether stringent or variable chromosome segregation occurs in polyploid thermophilic bacterium Thermus thermophilus was analyzed. A stable heterozygous strain (HL01) containing two antibiotic resistance markers at one gene locus was generated. The inheritance of the two alleles in the progeny of the heterozygous strain was then followed. During incubation without selection pressure, the fraction of heterozygous cells decreased and that of homozygous cells increased, while the relative abundance of each allele in the whole population remained constant, suggesting chromosome segregation had experienced random event. Consistently, in comparison with Bacillus subtilis in which the sister chromosomes were segregated equally, the ratios of DNA content in two daughter cells of T. thermophilus had a broader distribution and a larger standard deviation, indicating that the DNA content in the two daughter cells was not always identical. Further, the protein homologs (i.e., ParA and MreB) which have been suggested to be involved in bacterial chromosome partitioning did not actively participate in the chromosome segregation in T. thermophilus. Therefore, it seems that protein-based chromosome segregation machineries are less critical for the polyploid T. thermophilus, and chromosome segregation in this bacterium are not stringently controlled but tend to be variable, and random segregation can occur.
A Multivariate Genome-Wide Association Study of Wing Shape inDrosophila melanogaster
Authors: Pitchers William , Nye Jessica , Márquez Eladio J , Kowalski Alycia , Dworkin Ian , Houle David
Published: February 2019

Due to the complexity of genotype–phenotype relationships, simultaneous analyses of genomic associations with multiple traits will be more powerful and informative than a series of univariate analyses. However, in most cases, studies of genotype–phenotype relationships have been analyzed only one trait at a time. Here, we report the results of a fully integrated multivariate genome-wide association analysis of the shape of the Drosophila melanogaster wing in the Drosophila Genetic Reference Panel. Genotypic effects on wing shape were highly correlated between two different laboratories. We found 2396 significant SNPs using a 5% false discovery rate cutoff in the multivariate analyses, but just four significant SNPs in univariate analyses of scores on the first 20 principal component axes. One quarter of these initially significant SNPs retain their effects in regularized models that take into account population structure and linkage disequilibrium. A key advantage of multivariate analysis is that the direction of the estimated phenotypic effect is much more informative than a univariate one. We exploit this fact to show that the effects of knockdowns of genes implicated in the initial screen were on average more similar than expected under a null model. A subset of SNP effects were replicable in an unrelated panel of inbred lines. Association studies that take a phenomic approach, considering many traits simultaneously, are an important complement to the power of genomics.
Relativistic Study of the Spinless Salpeter Equation with a Modified Hylleraas Potential
Authors: Antia A. D. , Okon I. B. , Umoren E. B. , Isonguyo C. N.
Published: February 2019

We have solved the Spinless Salpeter Equation (SSE) with a modified Hylleraas potential within the Nikiforov–Uvarov method. The energy eigenvalues and the corresponding wave functions for this system expressed in terms of the Jacobi polynomial are obtained. With the help of an approximation scheme, the potential barrier has been evaluated. The results obtained can be applied in nuclear physics, chemical physics, atomic physics, molecular chemistry, and other related areas, for example, can be used to study the binding energy and interaction of some diatomic molecules. By adjusting some potential parameters, our potential reduces to the Rosen–Morse and Hulthen potentials. We have present also the numerical data on the energy spectra for this system.
Formation of Silver Nanoparticles in PVA-PEG Hydrogel under Electron Irradiation
Authors: Neimash V. B. , Kupianskyi H. D. , Olkhovyk I. V. , Styopkin V. I. , Lytvynchuk P. M. , Povarchuk V. Yu. , Roguts’kyi I. S. , Furmanov Yu. A. , Titarenko S. M.
Published: February 2019

The formation of silver nanoparticles in a hydrogel on the basis of polyvinyl alcohol and polyethylene glycol at its crosslinking under the electron irradiation has been studied using the optical spectroscopy and scanning electron microscopy methods. The growth of nanoparticles 40–70 nm in size and their clustering into aggregates about a few hundred nanometers in diameter are demonstrated. The total concentration of nanoparticles and their size correlate with the concentration of ionic silver in the initial solution and the electron irradiation dose. The formation of nanoparticles is interpreted as a result of the radiation-induced chemical reduction of silver in the solution that is spatially confined in the cells of a 3D microstructure in the crosslinked hydrogel. The radiation-crosslinked hydrogel demonstrates an antiseptic effect for 7 of 8 tested microorganisms at silver concentrations of 0.001–0.003 wt.%, which is at least an order of magnitude lower than effective concentrations of ionic and colloidal silvers.
Features of the Formation of Ohmic Contacts to n+-InN
Authors: Sai P. O. , Safryuk-Romanenko N. V. , But D. B. , Cywiński G. , Boltovets N. S. , Brunkov P. N. , Jmeric N. V. , Ivanov S. V. , Shynkarenko V. V.
Published: February 2019

We report about a study of the formation and current transport mechanism of ohmic contacts to n+-InN with electron concentrations of 2×1018, 8×1018, and 4×1019 cm−3. Pd/Ti/Au ohmic contacts are formed by the proposed approach of simultaneous magnetron metal deposition and in-situ temperature annealing, which allows obtaining a low contact resistivity (4.20±2.67)×10−6 Ohm· cm2. The additional rapid thermal annealing in the temperature interval 350–400 ∘C is used to improve further contact characteristics. Optimal parameters of the temperature treatment are determined by statistic methods. As for the current transport mechanism, the unusual growing temperature behavior of contact resistivity is observed in the wide temperature range 4.2–380K for each doping level of InN films. The mechanism of thermionic current flow explains the current transport through metal shunts, which is associated with the conducting dislocations. The extracted density of conducting metal shunts has a good agreement with experimental values of the screw and edge dislocation densities experimentally obtained by high-resolution X-ray diffraction. Additionally, from the obtained contact resistivity temperature dependences, we can argue about the metal, which penetrates dislocations and forms shunts.
Photoreactions of Macrocyclic Dyes on (1010) Wurtzite Surface – Interplay Between Conformation and Electronic Effects
Authors: Golovanova V. V. , Nazarchuk B. V. , Postnyi O. V. , Rantala T. T. , Tkachenko N. V. , Golovanov V. V.
Published: February 2019

Macrocyclic dyes such as phthalocyanine and porphyrin molecules are modeled on (1010) wurzite surfaces using the DFT and molecular dynamics approaches. It is found that the single dye anchored on the wurtzite surface stabilizes in an inclined geometry with its core facing the surface at a tilting angle of ca 60∘. The tilting of the dye relative to the crystal surface has a dual effect on the charge transfer from a chromophore to the semiconductor. Increasing the tilting angle leads to a stronger coupling between the lowest level of the semiconductor conduction band and dye’s LUMO, thus raising the tunneling probability of the electron injection. By contrast, the electrostatic interaction between units upon the tilting of macrocycles results in a lowering of the molecule LUMO level with respect to the conduction band minimum of the wurzite crystal, which may hinder the electron transfer. The type of a linker and peripheral substituents significantly affect the mutual conformation of the moieties, and their proper choice can facilitate the photoinduced charge transfer reactions.
Calculated Spectra of Hydrocarbon Components of Natural Gas
Authors: Kuyliev B. T. , Jumaboev A. J. , Khushvaktov Kh. A. , Meyliev L. O. , Absonov A. A. , Hudoyberdiev B. G.
Published: February 2019

The paper presents the calculated spectra of hydrocarbon components of a natural gas (NG), and they are compared with the experimental results. The results of experimental studies of NG show that the region of stretching vibrations of hydrocarbon С-Н bonds, despite the very high level of the Raman signal, is of little use for the quantitative and qualitative analysis. This is due to the fact that the structure of the bands in this region of the spectrum is very complex, and the methane bands with its suppressing content in NG dominate here. The spectra of weak bands of heavy hydrocarbons against the background of very intense bands of methane are almost not revealed. In full, it is difficult to take all the details into account, as can be seen from the previous one. Therefore, we paid a special attention to the determination of the molecular components of NG such as methane (CH4), ethane (C2H6), propane (C3H8), and butane (C4H10), by calculating the C–H vibrations and determining the spectral region, where they are located. The results of calculations confirm that the frequencies of C–H vibrations of heavy hydrocarbons (ethane, propane, and butane) do lie in the spectral range of 2500–3500 cm−1 of combinational frequencies.
Comparison of Formal and Informal Land Administration Systems in Lagos State: The Case of Epe Local Government Area
Authors: Ogbu Chukwuemeka Patrick , Iruobe Patience
Published: February 2019

The efficient harnessing of land resources remains key to unlocking the potential of economies in Sub-Saharan Africa. Land administration systems provide a veritable platform for coordinating the efforts aimed at maximising the overall value of a country’s land resources. Extant studies, however, provide scanty and unorganised insight into the problems and benefits of the formal and informal land administration systems co-existing in Nigeria and how they affect physical development on land. Using a cross-sectional survey, this study investigated the benefits and problems of formal and informal land administration systems in Epe, Lagos, and ascertained the relationship between the level of land development and land occupants’ type of occupancy (which may be formal or informal). A major problem of the formal land administration system is that to be allocated land; one needs to know a government official, while its key benefit is that anyone can be allocated land anywhere irrespective of their state of origin. Under the informal land administration system, the main problem is that additional “settlement(s)” are required before one can build on the land, while its key benefit is that one purchases land in the place of one’s choice. Using logistic regression analysis, it was observed that the level of development of land is independent of the type of occupancy held by the occupant. The study concludes that formal land administration system does not necessarily lead to higher land development than informal land administration. Future land formalisation policies should seek to optimise the merits and minimise the challenges of the two systems of land administration.
Compensation Theories and Expropriation of Customary Property Rights
Authors: Kabanga Lucky , Mooya Manya M
Published: February 2019

Market value is the most common compensation basis for expropriation of both private and customary property rights. Private property rights are generally exchangeable while customary property rights are conceptually not as exchangeable. It is hence critical to analyse the applicability of current compensation theories, which are founded on private property rights, to different property rights and in different social settings. By using existing literature and empirical evidence from Africa and other countries where customary property rights dominate, this paper undertakes a theoretical analysis of the applicability of existing compensation theories and the methodologies used to achieve the desired compensation goals. The analysis concludes that whilst current compensation theories are broadly applicable to customary property rights as they aim to protect property rights and prevent expropriatees from impoverishment, various ontological and methodological factors limit the realisation of these goals in settings dominated by customary properties. Such factors include ontology and dominance of customary property rights, use of market value as a compensation basis, and capacity of compensation assessors. Broadly, these factors lead to inadequate compensation and impoverishment of affected people.
Between Abuja and Lagos: Insights of Price and Value in Residential Real Estate
Authors: Onwuanyi Ndubisi
Published: February 2019

Nigeria’s most prominent real estate markets are Lagos and Abuja. Between the years 2011 to 2015 saw unusually steep prices and pronounced vacancies in Abuja’s high-end residential segment compared to Lagos’. This discrepancy suggests market differences which are deserving of investigation. This paper, therefore, comparatively examines these two markets by exploring the economic concepts of price and value which sustain the market system. The data was sourced by a questionnaire administered to estate surveyors and valuers as well as the asking prices from property archives. The main finding of this paper is that Abuja’s prices and rents significantly exceed Lagos’ despite it being a less economically productive city. One can conclude that the Lagos market is more resilient while Abuja’s buoyancy is more apparent than real.
Winter distribution of Steller's Eiders in the Varangerfjord, northern Norway
Authors: Heggøy Oddvar , Øien Ingar Jostein , Aarvak Tomas
Published: February 2019

Arctic warming and decreasing sea-ice cover along the Siberian coast in the Arctic Ocean leads to greater accessibility for operations such as oil drilling and traffic of tankers. This implies increasing risks for Steller’s Eider Polysticta stelleri wintering, moulting and staging along the coasts of the Varanger Peninsula, Norway. Steller’s Eiders were surveyed by monthly counts during winter and early spring 2016/2017 to investigate numbers and distribution throughout the winter. The highest number of wintering Steller’s Eiders was found in January, representing ~7 % of the European population. In February–April numbers were lower, but at a rather stable level. We found relatively little variation in distribution between months, although the birds were more evenly distributed along the coast later in winter. Mean flock size was significantly larger in January than in March and April. Feeding behaviour was exclusively observed in shallow water, generally at depths of up to 6 m. Areas of focus for an oil pollution emergency plan are pointed out and discussed.
A comparison of nontreponemal tests in cerebrospinal fluid for neurosyphilis diagnosis: equivalent detection of specific antibodies
Authors: Versiani Isadora , Cabral-Castro Mauro Jorge , Puccioni-Sohler Marzia
Published: February 2019

ABSTRACT Syphilis is a re-emerging sexually-transmitted infection, caused by the spirochete Treponema pallidum, that may penetrate early into the central nervous system. The venereal disease research laboratory test (VDRL) on the cerebrospinal fluid (CSF) is the most widely used for neurosyphilis diagnosis. We evaluated the performance of two other nontreponemal tests (rapid plasma reagin [RPR] and unheated serum reagin [USR] tests) in comparison with the VDRL in CSF. Methods: We analyzed CSF samples from 120 individuals based on VDRL reactivity in the CSF and the clinical picture of neurosyphilis. Results: High inter-rater reliability was found among all three tests, with equivalent sensitivity and specificity. Intraclass correlation coefficient for absolute agreement was 1 for VDRL versus USR, 0.99 for VDRL versus RPR, and 0.99 for RPR versus USR. Conclusions: Rapid plasma reagin and unheated serum reagin tests were identified as excellent alternatives for neurosyphilis diagnosis.
Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS)
Authors: Cruz Márcia Waddington , Pinto Marcus Vinicius , Pinto Luiz Felipe , Gervais Renata , Dias Moisés , Perez Carlos , Mundayat Rajiv , Ong Moh-Lim , Pedrosa Roberto Coury , Foguel Débora
Published: February 2019

ABSTRACT Transthyretin amyloidosis (ATTR) is characterized by the deposit of mutant or wild-type transthyretin that forms amyloid fibrils, which are extracellularly deposited within tissues and organs. Clinical manifestations of familial amyloid polyneuropathy vary according to the mutation, age at onset and geographical location. This study aimed to describe baseline disease characteristics of Brazilian patients with transthyretin familial amyloid polyneuropathy (ATTR-FAP) enrolled in the Transthyretin Amyloidosis Outcome Survey (THAOS). Methods: The THAOS is an international, noninterventional, longitudinal, observational, web-based registry designed to characterize ATTR. The outcome measures included demographics (age at symptom onset, gender, time from onset of symptoms to diagnosis, family history), genotype, and clinical characteristics (presence of amyloid deposit, frequency of misdiagnosis, presenting symptomatology). The analysis was conducted in a dataset from Brazilian patients (from November 2008 to January 2016). Results: One hundred and sixty participants (52.5% male) were included in the analysis. The majority of participants (90.6%) reported a positive family history of ATTR-FAP Median age at symptom onset was 32.5 years. Val30Met mutation was found in 91.9%. Misdiagnosis was observed in 26.6% of symptomatic patients. Over one-third (35.3%) of the misdiagnosed patients experienced a delay of more than one year before receiving a correct diagnosis. At presentation, 79.7% of the patients had motor, 87.5% sensory and 93.8% autonomic symptoms. Conclusion: ATTR-FAP in Brazil starts early, has a strong family history and the majority has Val30Met mutation. Misdiagnosis is common and the most common presentation is of a sensorimotor and autonomic neuropathy.
Dabigatran and warfarin in nonvalvular atrial fibrillation or atrial flutter in outpatient clinic practice in Brazil
Authors: Monteiro Jean Michell Correia , San-Martin Daniel Lordelo , Silva Beatriz Carneiro Gondim , Souza Ian Felipe Barbosa , Oliveira Filho Jamary , Jesus Pedro
Published: February 2019

ABSTRACT Objectives: To compare warfarin and dabigatran for thromboembolic event prevention in patients with nonvalvular atrial fibrillation or atrial flutter. Methods: This was a retrospective cohort of participants with nonvalvular atrial fibrillation or atrial flutter using either warfarin or dabigatran in a reference center in Brazil. Results: There were 112 patients (mean age 65.5 years), with 55.3% using warfarin. The median duration of follow-up was 1.9 years for warfarin and 1.6 years for dabigatran (p = 0.167). Warfarin patients had a higher median of medical appointments per year (8.3 [6.8-10.4] vs 3.1 [2.3-4.2], p < 0.001) and the frequency of minor bleeding was more than four times higher (17.7% vs 4.0%, p = 0.035). Among patients with prior stroke, those using warfarin had 2.6 times more medical appointments for person-years of follow-up (8.5 vs 3.3). There was no major bleeding or embolic event during follow-up period. Conclusion: The dabigatran group had a lower frequency of minor bleeding and number of medical appointments than the warfarin group, without more embolic events or major bleeding.
GBA mutations p.N370S and p.L444P are associated with Parkinson's disease in patients from Northern Brazil
Authors: Amaral Carlos Eduardo de Melo , Lopes Patrick Farias , Ferreira Juliana Cristina Cardoso , Alves Erik Artur Cortinhas , Montenegro Marcella Vieira Barroso , Costa Edmar Tavares da , Yamada Elizabeth Sumi , Cavalcante Fernando Otávio Quaresma , Santana-da-Silva Luiz Carlos
Published: February 2019

ABSTRACT Mutations of the GBA gene have been reported in patients with Parkinson's disease (PD) from a number of different countries, including Brazil. In order to confirm this pattern in a sample of PD patients from northern Brazil, we conducted a case-control study of the occurrence of the two most common mutations of the GBA gene (c.1226A>G; p.N370S and c.1448T>C; p.L444P) in a group of 81 PD patients and 81 control individuals, using PCR-RFLP, confirmed by the direct sequencing of the PCR products. In the patient group, three patients (3.7%) were heterozygous for the GBA c.1226A>G; p.N370S mutation, and three (3.7%) for GBA c.1448T>C; p.L444P Neither mutation was detected in the control group (p =0.0284). Patients with the c.1448T>C; p.L444P mutation showed a tendency to have an earlier disease onset, but a larger sample number is required to confirm this observation. Our results suggest an association between the GBA c.1226A>G; p.N370S and c.1448T>C; p.L444P mutations and the development of PD in the population of patients from the Northern Brazil.
Prevalência de sobrepeso e de obesidade no primeiro ano de vida nas Estratégias Saúde da Família
Authors: Camargos Ana Cristina Resende , Azevedo Bárbara Nayara Souza , Silva Darlene da , Mendonça Vanessa Amaral , Lacerda Ana Cristina Rodrigues
Published: February 2019

Resumo Introdução O sobrepeso e a obesidade infantil representam alguns dos principais problemas de saúde pública no mundo, porém se observa escassez de registros de prevalência no Brasil no primeiro ano de vida. Objetivo Verificar a prevalência de sobrepeso e de obesidade no primeiro ano de vida das crianças cadastradas nas Estratégias Saúde da Família e identificar se existe diferença entre os índices peso por idade, estatura por idade, peso/estatura por idade e índice de massa corporal (IMC) por idade em relação ao sexo, à faixa etária e ao nível socioeconômico. Método Estudo transversal, com dados de peso e estatura coletados da Caderneta de Saúde da Criança. Resultados A prevalência de sobrepeso e de obesidade foi de 7,2% pelo índice peso/estatura e de 4,8% pelo IMC. Crianças com nível socioeconômico A-B apresentaram maior IMC por idade quando comparadas às crianças do nível C (p = 0,048). Crianças entre 6 e 12 meses de idade apresentaram valores superiores de peso por idade (p = 0,02) e estatura por idade (p = 0,01) quando comparadas às crianças menores de 6 meses. Conclusão A prevalência de sobrepeso e de obesidade das crianças no primeiro ano de vida depende do índice utilizado para classificação. O nível socioeconômico pode interferir nos valores do IMC por idade, enquanto a faixa etária pode interferir nos índices peso por idade e estatura por idade.
Associação entre a qualidade de vida relacionada à saúde bucal e a capacidade para o trabalho de técnicos administrativos em educação: um estudo transversal
Authors: Palma Pamella Valente , Leite Isabel Cristina Gonçalves , Greco Rosangela Maria
Published: February 2019

Resumo Introdução Trabalhadores ativos constituem uma parcela importante da população que demanda os serviços de saúde. O estudo da relação entre saúde bucal e trabalho visa à melhoria da qualidade de vida e do desempenho profissional. Objetivo associar a capacidade para o trabalho com a qualidade de vida relacionada à saúde bucal de técnicos administrativos em educação de uma instituição de ensino superior de Minas Gerais. Método estudo transversal com 833 funcionários, com os quais foram coletados dados de identificação, socioeconômicos, demográficos, autopercepção e morbidade em saúde bucal. O impacto da saúde bucal na qualidade de vida foi avaliado pelo Oral Health Impact Profile (OHIP-14), e a capacidade de trabalho, pelo Índice de Capacidade para o Trabalho (ICT). Os dados foram analisados pelos testes Mann-Whitney e coeficiente de correlação de Spearman. Resultados 83% dos entrevistados possuíam ótima ou boa capacidade para o trabalho. Houve correlação positiva e significativa da autopercepção da saúde bucal com a autopercepção da saúde geral (p < 0,001) e negativa com o ICT (p = 0,026). Na análise de regressão, ICT total permaneceu significativo para o domínio dor física do OHIP-14. Conclusão capacidade para o trabalho foi associada ao domínio dor física. Condições sociodemográficas e de autopercepção também impactaram na qualidade de vida associada à saúde bucal.
Associação do tabagismo com biomarcadores REDOX e fatores de risco cardiometabólicos em idosos
Authors: Jacondino Camila Bittencourt , Schwanke Carla Helena Augustin , Closs Vera Elizabeth , Gomes Irênio , Borges Cristiane Alves , Gottlieb Maria Gabriela Valle
Published: February 2019

Resumo Introdução O tabagismo constitui a principal causa de morte evitável no mundo e é considerado um importante fator de risco para as doenças cardiovasculares (DCV). Objetivo Verificar a associação do tabagismo com sexo, metabolismo redox e fatores de risco cardiometabólicos de 381 idosos da Estratégia Saúde da Família de Porto Alegre/RS. Método Para categorizar o tabagismo, seguiram-se as recomendações do Center of Diseases Control (CDC). Os marcadores de estresse oxidativo investigados foram: produtos avançados da oxidação proteica (AOPP), metabólitos do óxido nítrico (NOx), capacidade antioxidante medida por meio do ensaio ferric reducing ability of plasma (FRAP). Fatores de risco cardiometabólicos também foram avaliados. Resultados Em relação ao sexo/fumo, foram mais frequentes as mulheres não fumantes (P = 0,001). Os homens ex-tabagistas apresentaram maiores concentrações de FRAP (P = 0,001), e os tabagistas, maior concentração de NOx, (0,012), menores médias de circunferência de cintura-CC (P = 0,017) e de índice de massa corporal-IMC (P = 0,003) e maior HDL-c (P = 0,003). Não foram verificados resultados significativos entre as mulheres. Conclusão Os idosos do sexo masculino tabagistas apresentaram menores valores de CC, IMC e HDL-c, porém os tabagistas apresentaram aumento da concentração do NO x, o qual é um biomarcador de estresse oxidativo associado a doenças cardiovasculares. Portanto, é preciso destacar a importância na prevenção e adesão à cessação de tabagismo para evitar comorbidades cardiovasculares.
Hepatites B e C nas áreas de três Centros Regionais de Saúde do Estado do Pará, Brasil: uma análise espacial, epidemiológica e socioeconômica
Authors: Gonçalves Nelson Veiga , Miranda Claudia do Socorro Carvalho , Guedes Juan Andrade , Silva Larissa de Cássia Tork da , Barros Elizabeth Maciel , Tavares Cileide Gomes da Mota , Palácios Vera Regina da Cunha Menezes , Costa Simone Beverly Nascimento da , Oliveira Helena Cunha , Xavier Marília Brasil
Published: February 2019

Resumo Introdução As hepatites virais são graves problemas de saúde pública e estão relacionadas às diferentes características socioeconômicas do território brasileiro. Objetivo Analisar a distribuição espacial das hepatites B e C e sua relação com o Índice de Desenvolvimento Humano Municipal (IDHM) nas áreas de três Centros Regionais de Saúde (CRS), no Estado do Pará, Brasil, de 2010 a 2014. Método Neste trabalho descritivo e transversal, foram utilizados dados do Sistema de Informação de Agravos de Notificação, do Ministério da Saúde, e do Censo 2010, do Instituto Brasileiro de Geografia e Estatística. Resultados As análises mostraram que o 11º CRS notificou o maior número de casos (60,9%). Os indivíduos mais acometidos por ambas as doenças foram do gênero feminino, pardos, adultos e com ensino fundamental. Os fatores de riscos mais significativos foram uso de medicamentos injetáveis e tratamentos dentário e cirúrgico. Foi observada dependência espacial entre o IDHM e os parâmetros da taxa de incidência das doenças, com autocorrelações diretas e indiretas. Assim, áreas com IDHM médio e baixo apresentaram altas taxas de incidência, sobretudo em municípios com intenso fluxo migratório, nas últimas décadas. Conclusão As análises foram eficazes para construir cenários epidemiológicos das doenças. Ressaltamos a necessidade de expandir o controle das hepatites nas áreas estudadas.
Occurrence of concavities on the lorica of two species of Testudinella (Rotifera, Monogononta, Testudinellidae)
Authors: Coelho Paula Nunes , Braghin Louizi Souza Magalhães , Lansac-Tôha Fabio Amodêo , Henry Raoul
Published: February 2019

Abstract: Testudinella is a taxon of Rotifera broadly distributed in Brazil. In a recent collection in marginal lakes connected to the Paranapanema River (São Paulo, Brazil), we found specimens of Testudinella mucronata and T. patina with concavities on their lorica. The objective of this study was to describe the concavities observed in individuals of both species and discuss their possible causes. Plankton samples were collected at two sampling stations, in the pelagic (PZ) and littoral (LZ) zones of the Panema and Coqueiral lakes; both of these lakes are ultra-oligotrophic and not polluted. For T. mucronata, 4% of individuals with concavities were found in the PZ of Coqueiral lake and 50% in the LZ of Panema lake. In T. patina, the proportion of specimens with concavities corresponded to 34% in the LZ of Panema lake and 17% in PZ of Coqueiral lake. In this study, we discussed that low water temperatures, predation events and/or recent hatching are factors that may justify the concavities in the lorica of specimens of our work.
Missionários americanos na Bahia: o bacharelado em administração da Escola de Administração da UFBA
Authors: Bertero Carlos Osmar , Barros Amon , Alcadipani Rafael
Published: February 2019

Resumo Por meio de uma historiografia, este trabalho analisa como os Estados Unidos apoiaram a criação da Escola de Administração da UFBA, contando ainda com o apoio da Escola de Administração de Empresas de São Paulo (EAESP), vista como disseminadora do modelo estadunidense de escolas de negócios no Brasil. Após a leitura dos documentos produzidos pela “missão” estadunidense na Bahia e de outras fontes históricas, especialmente o livro sobre a história da Escola de Administração da UFBA (SANTOS, BARRETO e BARRETO, 2009), concluímos que os estadunidenses enfrentaram vários obstáculos não antevistos. Concluímos mostrando como os “missionários” não sabiam lidar com as idiossincrasias das universidades públicas brasileiras e como tiveram também de lidar com interesses locais relativos especialmente à introdução de um bacharelado em Administração Pública e ao papel do Estado na regulação do ensino e da economia.
Confiança em contratos relacionais: um estudo teórico
Authors: Zanini Marco Tulio Fundão , Migueles Carmen Pires
Published: February 2019

Resumo O objetivo deste artigo é contribuir para uma melhor compreensão das questões relativas à confiança dentro das organizações, de modo a expandir e refinar constructos teóricos. A confiança é abordada em uma perspectiva econômica como mecanismo social de gestão. Buscamos compreender o papel da confiança na coordenação informal dos contratos relacionais. Abordamos a confiança como um elemento essencial para a execução de tarefas organizacionais específicas e observamos sua relação mediadora com o desempenho organizacional. Ao final, propomos um modelo analítico e concluímos que a confiança é um elemento central para a melhor compreensão dos contratos relacionais e que investimentos em um estilo de gestão baseado na confiança devem observar o contexto específico e a natureza das tarefas organizacionais.
Business models in the public domain: the public governance canvas
Authors: Martins Humberto Falcão , Mota João Paulo , Marini Caio
Published: February 2019

Abstract This study aims to put forward a public governance ontology, based on robust business literature and a structured public governance concept, to aid in improving understanding, communication, innovation, and measurements in public ventures. The ontology approach is combined with design science to develop a “public governance canvas model,” which conveys different descriptions of governance arrangements of given public ventures. The product of this research is a model that forms the ideal structure of new strategic management and information tools, as well as offers other benefits relating to measurement and evaluation. Finally, the canvas model is applied in three different institutional contexts of public management. Further development of this review could be accomplished by applying this model to organizations that generate important outcomes for both practitioners and academics.
Dimensões da inovação em organizações da justiça: proposição de um modelo teórico-metodológico
Authors: Castro Marilú Pereira , Guimarães Tomas Aquino
Published: February 2019

Resumo A morosidade das decisões judiciais e a desigualdade de acesso aos serviços prestados pelas organizações da Justiça expõem fragilidades do sistema de Justiça brasileiro. A inovação é colocada como forma de enfrentar a crise, acreditando que, uma vez adotada, pode influenciar o desempenho das organizações da Justiça. Assim, o objetivo deste artigo é propor um modelo teórico-metodológico que aponte dimensões que influenciam o processo de inovação em organizações da Justiça. A premissa é de que atores, fatos e variáveis de natureza política, social e econômica, vinculados a distintos níveis de análise - institucional, interorganizacional, organizacional e individual - influenciam a inovação na Justiça. O sentimento de identidade e os objetivos comuns podem estimular ou restringir a interação e a cooperação entre atores que estão inseridos em uma cultura de normas e valores específicos do sistema de justiça. O modelo foi construído com base na teoria da inovação e no institucionalismo organizacional, identificando-se 5 dimensões que podem afetar a inovação em organizações da Justiça: ambiente institucional; recursos organizacionais; relações de cooperação; liderança; e comportamento inovador. Ao final, são formuladas proposições a testar em pesquisas.