bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk of epilepsy in rheumatoid arthritis: a meta-analysis of population based studies and bioinformatics analysis
Authors: Zhao Huawei , Li Shan , Xie Meijuan , Chen Rongrong , Lu Haimei , Wen Chengping , Filiano Anthony J. , Xu Zhenghao
Published: February 2020

Background:

An increasing number of studies support an association between rheumatoid arthritis (RA) and brain disorders. This study aims to determine the association between RA and epilepsy.

Methods:

A comprehensive search of databases in both English and Chinese was performed. Data from the selected studies were extracted and analyzed independently by two authors. Genes associated with epilepsy and RA were also collected and analyzed.

Results:

We included six nationwide population based studies ( n = 7,094,113 cases in total) for the meta-analysis. The risk of epilepsy was increased in RA patients [risk ratio (RR) = 1.601; 95% confidence interval (CI): 1.089–2.354; p = 0.017; n = 3,803,535 cases] and children born to mothers with RA (RR = 1.475; 95% CI: 1.333–1.633; p < 0.001, n = 3,290,578 cases). Subgroup analysis and meta-regression showed the RR of epilepsy in RA was negatively correlated with age. Furthermore, we found that 433 identified genes in a coexpression network from the hippocampi of 129 epileptic patients were enriched in the RA and related Kyoto Encyclopedia of Genes and Genomes pathways, while 13 genes (mainly related to inflammatory cytokines and chemokines) were identified as potential key genes bridging the RA and epilepsy.

Conclusions:

Our study, utilizing meta-analysis and bioinformatical data, highlights a close association between epilepsy and RA. Further studies are still warranted to expand these findings, especially for a population that is exposed to RA during fetal and childhood periods.
The multi-sourcing journey of a European retailer: A roller coaster ride or smooth sailing?
Authors: Plugge Albert
Published: February 2020

During the last decade, the scope of IT outsourcing arrangements evolved from a dyadic client–vendor relationship to a multi-sourcing environment characterized by sourcing inter-dependent services from multiple vendors. This case study addresses the journey of a large client firm in the retail sector who experienced that managing a multi-sourcing arrangement differs significantly from managing bilateral (i.e. dyadic) relationships. The journey consists of three phases: the initiation phase (2008–2010), which can be characterized as stressful and intense; the adaption phase (2010–2012); and the stabilization phase (2012–2015). The case describes actual situations along the journey, including the client’s previous experience, the deal making, the challenges and conflicts faced by the client and their vendors, and the strategic change toward a collaborative type of multi-sourcing arrangement.
Computerised emotional well-being and substance use questionnaires in young Indigenous and non-Indigenous Australian adults
Authors: Davison Belinda , Liddle Robyn , Fitz Joseph , Singh Gurmeet R
Published: February 2020

Background:

Mental health disorders rank among the most substantial causes of morbidity and mortality worldwide. Almost half of Australian adults experience mental illness at some point in their lifetime, with Indigenous Australians disproportionally affected. Thus, it is imperative that effective, acceptable screening tools are used, which are tailored to the target population.

Objectives:

This research investigates the methodology of computerised questionnaires in assessing the emotional well-being and substance use in Indigenous and non-Indigenous young adults.

Methods:

Cross-sectional data from young adults (21–28 years) in the Life Course Program, Northern Territory, Australia, are presented. Through an extensive consultation process, validated questionnaires were adapted to a computerised format suitable for both remote and urban residing Indigenous and non-Indigenous adults.

Results:

Of the 576 participants (459 Indigenous, 117 non-Indigenous) available for assessment, high consent rates were seen, with completion rates >86%. One in three young adults in this cohort were highlighted as ‘at risk’ of psychological distress, and one in five as ‘at risk’ of suicidal ideation or self-harm.

Conclusion:

The target population of this study were at a critical age with high levels of psychological distress and suicidal ideation reported, particularly in Indigenous young adults. This simple, user-friendly, pictorial programme allowed assessment of a sensitive topic anonymously, while simultaneously collating data and identifying those at high risk, irrespective of literacy level or cultural background.
Platypnea-orthodeoxia syndrome after open prostatectomy and cystolithotomy: Coincidence or unknown pathophysiology?
Authors: Flores Ismael P , Maciel Alexandre T
Published: February 2020

A few cases of platypnea-orthodeoxia syndrome have been described in the literature, some of them after thoracic or upper abdominal surgeries. In most cases, hypoxemia in the upright or sitting position, which is the main clinical symptom for this uncommon diagnosis, is usually related to a dynamic right to left cardiac shunt induced by anatomical changes in the relative position between the inferior vena cava and the atria in the presence of a patent foramen ovale. In this case report, we describe a situation in which platypnea-orthodeoxia syndrome developed acutely before surgery but that became severely exacerbated after an open urologic surgery without a clear acute anatomical change that could be responsible for triggering the syndrome. This case might suggest that the pathophysiology of acute platypnea-orthodeoxia syndrome is not completely elucidated and that other possible triggers for acute clinical manifestation in addition to acute anatomical thoracic changes must be explored.
White Women Who Lead: God, Girlfriends, and Diversity Projects in a National Evangelical Ministry
Authors: Burke Kelsy , McDowell Amy
Published: February 2020

A robust body of literature has used feminist analysis to study white evangelical women in the United States, but few of these studies have addressed the reproduction of racial inequality. Beginning with the assumption that women-led evangelical ministries are racialized organizations, the authors examine the relationship between racial and gender ideologies and the messages of white evangelical women leaders at the IF:Gathering, a popular annual Christian women’s conference in the United States. On the surface, the women who lead IF embody a contradiction: they support the conservative gender ideology of evangelicalism while challenging this religious tradition by encouraging all Christian women, regardless of race, to act as leaders within their communities. However, the authors’ in-depth content analysis of live-streamed and video-recorded conference sessions reveals that the mostly white speakers at IF use race to credential their leadership. Speakers draw from a mixture of racial and gender ideologies to stress the importance of telling diverse “girlfriends” about Jesus and rescuing women of color “in the trenches” (those who are from the global South or living in U.S. cities) from poverty or sexual exploitation. The findings reveal how potentially progressive and empowering messages at a women-led evangelical organization limit the definition and scope of women’s leadership and reinforce the white patriarchal status quo.
Standardised neonatal parenteral nutrition formulations – Australasian neonatal parenteral nutrition consensus update 2017
Authors: Bolisetty Srinivas , Osborn David , Schindler Tim , Sinn John , Deshpande Girish , Wong Chee Sing , Jacobs Susan E. , Phad Nilkant , Pharande Pramod , Tobiansky Rodney , Luig Melissa , Trivedi Amit , Mcintosh Joanne , Josza Eszter , Opie Gillian , Downe Lyn , Andersen Chad , Bhatia Vineesh , Kumar Prasanna , Malinen Katri , Birch Pita , Simmer Karen , McLeod Gemma , Quader Suzanne , Rajadurai Victor Samuel , Hewson Michael Patrick , Nair Arun , Williams Megan , Xiao Jing , Ravindranathan Hari , Broadbent Roland , Lui Kei
Published: February 2020

Background

The first consensus standardised neonatal parenteral nutrition formulations were implemented in many neonatal units in Australia in 2012. The current update involving 49 units from Australia, New Zealand, Singapore, Malaysia and India was conducted between September 2015 and December 2017 with the aim to review and update the 2012 formulations and guidelines.

Methods

A systematic review of available evidence for each parenteral nutrient was undertaken and new standardised formulations and guidelines were developed.

Results

Five existing preterm Amino acid-Dextrose formulations have been modified and two new concentrated Amino acid-Dextrose formulations added to optimise amino acid and nutrient intake according to gestation. Organic phosphate has replaced inorganic phosphate allowing for an increase in calcium and phosphate content, and acetate reduced. Lipid emulsions are unchanged, with both SMOFlipid (Fresenius Kabi, Australia) and ClinOleic (Baxter Healthcare, Australia) preparations included. The physicochemical compatibility and stability of all formulations have been tested and confirmed. Guidelines to standardise the parenteral nutrition clinical practice across facilities have also been developed.

Conclusions

The 2017 PN formulations and guidelines developed by the 2017 Neonatal Parenteral Nutrition Consensus Group offer concise and practical instructions to clinicians on how to implement current and up-to-date evidence based PN to the NICU population.
A systematic literature review of spinal brace/orthosis treatment for adults with scoliosis between 1967 and 2018: clinical outcomes and harms data
Authors: McAviney Jeb , Mee Johanna , Fazalbhoy Azharuddin , Du Plessis Juan , Brown Benjamin T.
Published: February 2020

Background

There is a paucity of literature regarding the conservative management of adult scoliosis. The authors review and summarize the literature from 1967 to 2018 on the clinical outcomes of spinal brace/orthosis use in this subgroup of the population.

Methods

CINAHL, Embase, CENTRAL, PubMed and PEDro were searched from database inception to the 30th of October, 2018. A combination of medical subject heading terms and keywords pertaining to three core concepts (adult, scoliosis, and braces/orthoses) were used in the search. Studies were included if A) clinical outcomes were collected from B) participants ≥18 years C) receiving spinal brace/orthosis treatment for D) primary degenerative (de novo) scoliosis or progressive idiopathic scoliosis. A step-wise screening process was employed which involved a title and abstract screen for relevancy followed by a full text eligibility appraisal by two authors. Data were extracted, and a risk of bias assessment was performed on the included cohort studies using the Newcastle-Ottawa Scale. Given the overall level and quality of the available evidence, conclusions were drawn based on a qualitative summary of the evidence.

Results

Ten studies (four case reports and six cohort studies) were included which detailed the clinical outcomes of soft (2 studies) or rigid bracing (8 studies), used as a standalone therapy or in combination with physiotherapy/rehabilitation, in 339 adults with various types of scoliosis. Most studies included female participants only. Commonly reported outcomes were pain (7 studies), function (3 studies) and Cobb angles (3 studies), with follow-up times ranging from 2 days to 17 years. Brace wear prescriptions ranged from 2 to 23 h per day, and there was mixed brace-compliance reported. Most studies reported modest or significant reduction in pain and improvement in function at follow-up. There were mixed findings with regards to Cobb angle changes in response to bracing. Participants from one study noted discomfort associated with bracing. Each of the six cohort studies demonstrated a high risk of bias.

Conclusion

There is evidence to suggest that spinal brace/orthosis treatment may have a positive short – medium term influence on pain and function in adults with either progressive primary (de novo) degenerative scoliosis or progressive idiopathic scoliosis. At this point in time the evidence is of low quality and has been focused primarily on female patients with thoracolumbar and lumbar curves. More granular statements regarding the efficacy of different brace types or manufacturers, or the effect of this therapy on different curve types cannot be determined based on the current literature. Properly constructed prospective trials are required to better understand the efficacy of bracing in adult scoliosis.
Epidemiology, classification, treatment and mortality of distal radius fractures in adults: an observational study of 23,394 fractures from the national Swedish fracture register
Authors: Rundgren Johanna , Bojan Alicja , Mellstrand Navarro Cecilia , Enocson Anders
Published: February 2020

Background

Distal radius fractures are the most common of all fractures. Optimal treatment is still debated. Previous studies report substantial changes in treatment trends in recent decades. Few nation-wide studies on distal radius fracture epidemiology and treatment exist, none of which provide detailed data on patient and injury characteristics, fracture pattern and mortality. The aim of this study was to describe the epidemiology, fracture classification, current treatment regimens and mortality of distal radius fractures in adults within the context of a large national register study.

Methods

We performed a descriptive study using prospectively registered data from the Swedish fracture register. Included were all non-pathological distal radius fractures registered between January 1st 2015 and December 31st 2017 in patients aged 18 years and above. Nominal variables were presented as proportions of all registered fractures.

Results

A total of 23,394 distal radius fractures in 22,962 patients were identified. The mean age was 62.7 ± 17.6 years for all, 65.4 ± 16.0 for women and 53.6 ± 20.0 for men. A simple fall was the most common cause of injury (75%, n = 17,643/23,394). One third (33%, n = 7783/21,723) of all fractures occurred at the patients’ residence. 65% (n = 15,178/23,394) of all fractures were classified as extra-articular AO-23-A, 12% (n = 2770/23,394) as partially intra-articular AO-23-B and 23% (n = 5446/23,394) as intra-articular AO-23-C. The primary treatment was non-surgical for 74% (n = 17,358/23,369) and surgical for 26% (n = 6011/23,369) of all fractures. Only 18% of the AO-23-A fractures were treated surgically, compared to 48% of the AO-23-C fractures. The most frequently used surgical method was plate fixation (82%, n = 4954/5972), followed by pin/wire fixation (8.2%, n = 490/5972), external fixation (4.8%, n = 289/5972) and other methods (4.0%, n = 239/5972). The overall 30-day mortality was 0.4% (n = 98/23,394) and the 1-year mortality 2.9% (n = 679/23,394).

Conclusion

This nation-wide observational study provides comprehensive data on the epidemiology, fracture classification and current treatment regimens of distal radius fractures in a western European setting. The most common patient was an eldery woman who sustained a distal radius fracture through a simple fall in her own residence, and whose fracture was extra-articluar and treated non-surgically.
Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction
Authors: Connelly Kim A. , Zhang Yanling , Desjardins Jean-François , Nghiem Linda , Visram Aylin , Batchu Sri N. , Yerra Verra G. , Kabir Golam , Thai Kerri , Advani Andrew , Gilbert Richard E.
Published: February 2020

Background and aims

Sodium–glucose linked cotransporter-2 (SGLT2) inhibitors reduce the likelihood of hospitalization for heart failure and cardiovascular death in both diabetic and non-diabetic individuals with reduced ejection fraction heart failure. Because SGLT2 inhibitors lead to volume contraction with reductions in both preload and afterload, these load-dependent factors are thought to be major contributors to the cardioprotective effects of the drug class. Beyond these effects, we hypothesized that SGLT2 inhibitors may also improve intrinsic cardiac function, independent of loading conditions.

Methods

Pressure–volume (P–V) relationship analysis was used to elucidate changes in intrinsic cardiac function, independent of alterations in loading conditions in animals with experimental myocardial infarction, a well-established model of HFrEF. Ten-week old, non-diabetic Fischer F344 rats underwent ligation of the left anterior descending (LAD) coronary artery to induce myocardial infarction (MI) of the left ventricle (LV). Following confirmation of infarct size with echocardiography 1-week post MI, animals were randomized to receive vehicle, or the SGLT2 inhibitor, empagliflozin. Cardiac function was assessed by conductance catheterization just prior to termination 6 weeks later.

Results

The circumferential extent of MI in animals that were subsequently randomized to vehicle or empagliflozin groups was similar. Empagliflozin did not affect fractional shortening (FS) as assessed by echocardiography. In contrast, load-insensitive measures of cardiac function were substantially improved with empagliflozin. Load-independent measures of cardiac contractility, preload recruitable stroke work (PRSW) and end-systolic pressure volume relationship (ESPVR) were higher in rats that had received empagliflozin. Consistent with enhanced cardiac performance in the heart failure setting, systolic blood pressure (SBP) was higher in rats that had received empagliflozin despite its diuretic effects. A trend to improved diastolic function, as evidenced by reduction in left ventricular end-diastolic pressure (LVEDP) was also seen with empagliflozin. MI animals treated with vehicle demonstrated myocyte hypertrophy, interstitial fibrosis and evidence for changes in key calcium handling proteins (all p < 0.05) that were not affected by empagliflozin therapy.

Conclusion

Empagliflozin therapy improves cardiac function independent of loading conditions. These findings suggest that its salutary effects are, at least in part, due to actions beyond a direct effect of reduced preload and afterload.
FOXM 1 induces Vasculogenic mimicry in esophageal cancer through β-catenin /Tcf4 signaling
Authors: Cheng Lili , Wang Qi , Tao Xiaoying , Qin Yanzi , Wu Qiong , Zheng Dafang , Chai Damin , Zhang Yong , Lu Dongbing , Ci Hongfei , Wang Zhiwei , Ma Jia , Wang Danna , Cheng Zenong , Wu Shiwu , Tao Yisheng
Published: February 2020

Objective

To investigate the role of FOXM1, β-catenin and TCF4 in esophageal cancer (EC) and their relationship to VM (Vasculogenic Mimicry).

Methods

CCK-8 were performed to examine EC cell proliferation in FOXM1 silenced cells. EC cell migration and invasion were investigated through wound healing and Transwell assays, respectively. The formation of pipe like structures were assessed in 3D cultures. The expression of Foxm1, β-catenin, Tcf4 and E-cadherin were investigated through western blot, RT-qPCR and immunohistochemistry (IHC) staining. The relationship between FOXM1 expression, clinic-pathological features, and overall survival (OS) were further analyzed.

Results

A loss of FOXM1 expression correlated with the OS of ESCC patients. FOXM1 silencing led to a loss of cell growth and suppressed cell migration and invasion in ESCC cells. VM structures were identified in ESCC tissues and human EC cell lines. Mechanistically, FOXM1 was found to promote tumorigenesis through the regulation of β-catenin, Tcf4, and E-cadherin in EC cells, leading to the formation of VM structures.

Conclusions

These findings highlight FoxM1 as a novel therapeutic target in ESCC.
Clinicopathological features of primary thyroid Burkitt’s lymphoma: a systematic review and meta-analysis
Authors: Hayashi Toshitetsu , Hirokawa Mitsuyoshi , Kuma Seiji , Higuchi Miyoko , Suzuki Ayana , Kanematsu Risa , Kudo Takumi , Katsuki Naomi , Haba Reiji , Miyauchi Akira
Published: February 2020

Background

Primary thyroid Burkitt’s lymphoma (BL) is an extremely rare and highly aggressive form of non-Hodgkin’s lymphoma; only isolated case reports are available for patients with this disease.

Methods

We analyzed the clinicopathological features of thyroid BL by conducting a meta-analysis of 21 known patients (including ours) and compared them to those of extrathyroidal BL.

Results

There were 13 men and 8 women with a median age of 39.3 years (range, 6–75 years). The median follow-up was 46.5 months (range, 0.5–361 months). Six patients (28.6%) had stage I disease, 2 (9.5%) had stage II, 2 (9.5%) had stage III, and 11 (52.4%) had stage IV. Five of 7 tested patients with thyroid BL (71.4%) had histological evidence of underlying Hashimoto’s thyroiditis. Ki-67 labeling indices exceeding 90% in all 19 patients tested (100%). Fluorescence in situ hybridization performed on 12 patient samples revealed that all (100%) had MYC rearrangement. Among the 16 patients for whom follow-up data were available, 4 died of disease-related causes. Kaplan-Meier analysis revealed that the 12- and 60-month overall survival rates for patients with thyroid BL were 87.5 and 70.7%, respectively.

Conclusions

Ours was the largest study of thyroid BL and its detailed clinicopathological features to date. Thyroid BL is not associated with underlying Epstein-Barr virus infection but is closely linked to Hashimoto’s thyroiditis; patients generally have good overall survival and respond well to intensive chemotherapy. The correct pathological diagnosis is essential for treatment selection and outcome improvement.
Optimal location of a thin rigid inclusion for a problem describing equilibrium of a composite Timoshenko plate with a crack
Authors: Lazarev Nyurgun , Romanova Natalyya , Semenova Galina
Published: February 2020

We consider equilibrium problems for a cracked composite plate with a thin cylindrical rigid inclusion. Deformation of an elastic matrix is described by the Timoshenko model. The plate is assumed to have a through crack that does not touch the rigid inclusion. In order to describe mutual nonpenetration of the crack faces we impose a boundary condition in the form of inequality on the crack curve. For a family of appropriate variational problems, we analyze the dependence of their solutions on the location of the rigid inclusion. We formulate an optimal control problem with a cost functional defined by an arbitrary continuous functional on the solution space, while the location parameter of inclusion is chosen as the control parameter. The existence of a solution to the optimal control problem and a continuous dependence of the solutions in a suitable Sobolev space with respect to the location parameter are proved.
Mesh-adapted stress analysis of multilayered plates using a layerwise model
Authors: Salha Lucille , Bleyer Jérémy , Sab Karam , Bodgi Joanna
Published: February 2020

This paper proposes a new finite-element modelling of a recent layerwise model for multilayered plates. This layerwise model is built from a specific 3D stress-field expansion along the thickness direction and involves, in particular, interlaminar transverse shear and out-of-plane stresses as generalized stresses. Its main feature is that 3D equilibrium equations and free-edge boundary conditions are directly taken into account into the stress-based construction of the model. A dual displacement-based finite-element discretization is implemented using the FEniCS software package and a remeshing strategy is proposed based on a novel error indicator. The error indicator is built based on the 3D stress field directly deduced from the layerwise generalized stresses and compared to a reconstructed stress field based on the model generalized displacements. The proposed error indicator is shown to identify the most critical parts of a laminate structure associated with complex 3D stress fields such as boundaries or stress concentration/singularity regions (near free-edges or delamination fronts). Through the combination of thickness discretization and in-plane mesh refinement in regions of interest, the proposed framework therefore offers an attractive alternative to 3D solid finite elements for an accurate prediction of stress states in composite laminates.
“It’s like heaven over there”: medicine as discipline and the production of the carceral body
Authors: Glenn Jason E. , Bennett Alina M. , Hester Rebecca J. , Tajuddin Nadeem N. , Hashmi Ahmar
Published: February 2020

Background

Correctional systems in several U.S. states have entered into partnerships with Academic Medical Centers (AMCs) to provide healthcare for people who are incarcerated. This project was initiated to better understand medical trainee perspectives on training and providing healthcare services to prison populations at one AMC specializing in the care of incarcerated patients: The University of Texas Medical Branch at Galveston (UTMB). We set out to characterize the attitudes and perceptions of medical trainees from the start of their training until the final year of Internal Medicine residency. Our goal was to analyze medical trainee perspectives on caring for incarcerated patients and to determine what specialized education and training is needed, if any, for the provision of ethical and appropriate healthcare to incarcerated patients.

Results

We found that medical trainees grapple with being beneficiaries of a state and institutional power structure that exploits the neglected health of incarcerated patients for the benefit of medical education and research. The benefits include the training opportunities afforded by the advanced pathologies suffered by persons who are incarcerated, an institutional culture that generally allowed students more freedom to practice their skills on incarcerated patients as compared to free-world patients, and an easy compliance of incarcerated patients likely conditioned by their neglect. Most trainees failed to recognize the extreme power differential between provider and patient that facilitates such freedom.

Conclusions

Using a critical prison studies/Foucauldian theoretical framework, we identified how the provision/withholding of healthcare to and from persons who are incarcerated plays a major role in disciplining incarcerated bodies into becoming compliant medical patients and research subjects, complacent with and even grateful for delayed care, delivered sometimes below the standard best practices. Specialized vulnerable-population training is sorely needed for both medical trainees and attending physicians in order to not further contribute to this exploitation of incarcerated patients.
Exo- and endoglucanase production by Curvularia affinis using bean (Phaseolus vulgaris L.) waste biomass
Authors: Alawlaqi M. M. , Alharbi Asmaa A.
Published: February 2020

Background

In many countries, agricultural residues are generated in large quantities, and most of these are underutilized and considered waste, especially in developing countries.

Result

In this study,Curvularia affiniswas isolated from the leaves ofPhaseolus vulgarisL. beans and identified using 18S rRNA sequencing.C. affiniswas tested for exo- and endoglucanase production using biomass of bean waste compared with the use of microcrystalline cellulose (MCC) and carboxymethylcellulose (CMC) as its growth substrates.C. affiniswas better able to produce exo- and endoglucanase enzymes on bean waste biomass than on MCC and CMC. The highest activities of exo- and endoglucanase were detected with substrate concentrations 2% using MCC or CMC and with 4% using bean waste. The optimum incubation period for enzymes activity was 6 days with MCC or CMC (activity was 5.90 and 2.99 U/g of exoglucanase and endoglucanase, respectively) and 8 days with bean waste where activity was 3.64 U/g and 0.92 U/g of exoglucanase and endoglucanase, respectively. Exo- and endoglucanase production showed the highest activity at pH 5–6. In process wherein surfactant (Tween 80) was used, the exoglucanase activity gradually increased from 5.92 U/g to 6.20 U/g and then decreased to 5.70 U/g at 0.50% compared with that using the MCC substrate. The exoglucanase activity gradually increased from 3.80 U/g at 0.0% to 4.12 U/g at 0.20% and then decreased to 3.01 U/g at 0.50% Tween 80 using bean waste. Pretreated bean biomass also yielded higher enzyme production than the non-pretreated biomass. Alkaline-pretreated biomass showed the highest enzyme production compared with acid-treated residues, followed by the H2O2-treated ones.

Conclusion

The study concluded thatC. affinisproduce exo- and endoglucanase enzymes using cheap and abundant biomass of beans. Moreover, optimization of enzymes indicated that pretreatment of biomass bean biomass is a good choice process for enhanced enzymes productivity.
Spatial distribution and sources of tsunami deposits in a narrow valley setting - insight from 2011 Tohoku-oki tsunami deposits in northeastern Japan
Authors: Abe Tomoya , Goto Kazuhisa , Sugawara Daisuke
Published: February 2020

Sedimentary processes and spatial distributions of tsunami deposits in valleys have poorly been understood despite many paleo-tsunami deposits have recently been discovered from sedimentary sequences in valleys. We conducted an exhaustive investigation of 2011 Tohoku-oki tsunami deposits in a narrow valley at the south end of Sendai Plain, northeastern Japan, to collect sedimentological data of the tsunami deposits in the valley and to correlate them with tsunami inundation and associated sedimentary processes. The tsunami deposits were investigated at 174 sites to cover the entire inundation area of the narrow valley. We analyzed thickness, sedimentary structures, and grain size of the tsunami deposits to correlate their spatial variation with tsunami flow hydrodynamics and topographic features. The tsunami deposits, composed of sand and mud layers, were found to be 0–40 cm thick. Sand thickness generally decreased inland with local fluctuation. The sand layer was mostly composed of single unit on the upper main valley and sub-valleys, although it was mainly composed of 2–6 sub-units on the lower main valley and in the pond. Mud thickness is strongly controlled by local sources, namely, the rice paddy and the pond. The depositional area of the mud layer coincides with the distribution of the rice paddies and the pond location. The mud layer also considerably thicker in and around the pond. These results indicate that sediment thickness and sedimentary structures are highly varied on a local scale, but they are generally controlled by local topography. Sediment budget in the valley was estimated, and it may provide implications to general sedimentary process. Total depositional volume of the tsunami sand deposited on land is half of the volume of sediments disappeared from the sandy beach and sand dune, suggesting the rest must have been discharged into the sea by the backwash. Spatial distribution of sediment thickness and sedimentary structures as well as sedimentary processes inferred from 2011 Tohoku-oki tsunami deposits will benefit searching and identification of paleo-tsunami deposits in valleys of other coastal environments.
Using the Flipped Classroom Model in the History Course: A Learning Experience
Authors: Erol-Sahin Ayşegul Nihan
Published: February 2020

The flipped classroom model is an educational model in which students study at their homes and reinforce their knowledge in the classroom with exercises and activities. This model is currently being used by many Turkish schools, especially the ones that give information technologies education. In this study, it is aimed to understand the learning experience by using this model in history lessons in higher education. For research purposes, 5 weeks long program was modified according to the Flipped Classroom (FC) model. This program was implemented and the views and opinions of the participants were collected with a semi-structured questionnaire. The study group is comprised of students that took Ataturk’s Principles and the History of the Turkish Revolution (APHTR) Course during the 2016-2017 fall period at Gazi University in Turkey. Phenomenological analysis was used for data analysis. The results show that the most of the participants see many opportunities in this model. These include the permanent learning, entertaining lessons, interaction, functionality, and high motivation. But the model also poses challenges. Those challenges are problems regarding the long educational videos, wrong content, technical problems, and activities. The participants recommended videos to include more animation and to be shorter, and activities to be improved.
ANALISIS FAKTOR KEPEMIMPINAN OTENTIK DAN PERSEPSI DUKUNGAN ORGANISASI PADA WORK ENGAGEMENT STAF ORGANISASI PERHOTELAN DENGAN EFIKASI DIRI SEBAGAI MEDIATORNYA
Authors: Andamari Sri Respati
Published: February 2020

Abstract. This study aims to look at the effect of authentic leadership variables and perceptions of organizational support on staff engagement work in hospitality organizations by using self-efficacy as a moderator. This is because an increase in the number of tourists, both domestic and foreign, has encouraged competition for the quality of services in Yogyakarta, including hotels as accommodation. This study looks at the influence of organizations and the ability of individuals to increase work engagement on staff of hospitality organizations. Specifically, the variables measured to see organizational influence are authentic leadership and perceived organizational support. The variable used to see the ability of individuals who influence work engagement is self-efficacy. The results of this study indicate a significant correlation of each variable on work engagement. However, self-efficacy is less able to act as an effective moderator and more a strong predictor for work engagement variables. In addition, the results of the study also showed that perceived organizational support, authentic leadership and self-efficacy were able to influence work engagement by 28.8% together. Abstrak. Penelitian ini bertujuan untuk melihat pengaruh variabel kepemimpinan otentik dan persepsi dukungan organisasi pada work engagement staf di organisasi perhotelan dengan menggunakan efikasi diri sebagai moderatornya. Hal ini dikarenakan peningkatan jumlah wisatawan baik domestik maupun mancanegara telah mendorong persaingan akan kualitas jasa pelayanan di Yogyakarta termasuk di dalamnya adalah hotel sebagai akomodasi. Penelitian ini melihat  pengaruh dari organisasi dan kemampuan individu untuk meningkatkan work engagement pada staf organisasi perhotelan. Secara khusus, variabel yang diukur untuk melihat pengaruh organisasi adalah kepemimpinan otentik dan persepsi dukungan organisasi. Variabel yang digunakan untuk melihat kemampuan individu yang berpengaruh pada work engagement adalah efikasi diri. Hasil dari penelitian ini menunjukkan adanya korelasi yang signifikan dari masing-masing variabel terhadap work engagement. Namun demikian, efikasi diri kurang dapat berperan sebagai moderator yang efektif dan lebih menjadi prediktor yang kuat untuk variabel work engagement. Selain itu, hasil penelitian juga menunjukkan bahwa persepsi dukungan organisasi, kepemimpinan otentik dan efikasi diri mampu mempengaruhi work engagement sebesar 28,8% secara bersama-sama.
MEDIATION EFFECT OF JOB SATISFACTION ON ORGANIZTIONAL CITIZENSHIP BEHAVIOUR
Authors: Hartantyo Leo Tri , Sari Erita Yuliaseti Diah , Widiana Herlina Siwi
Published: February 2020

An organization always need good employees to achieve the goals, Willingness to work optimally, being able to volunteer to work, not just fixing on his duties and responsibilities as a member of the organization becomes important. This research aims to look at the effect of job satisfaction in mediating the relationship between Islamic work ethics (IWE) and perceived organizational support (POS) on Organizational Citizenship Behavior (OCB). A total 64 manufacturing company employees participated in the study. The results showed that job satisfaction can be a mediator between IWE and POS on OCB. It was found that the effect of IWE on OCB directly is more significant than indirect relationship. Conversely, impact of POS on OCB indirectly is more significant than direct relationship. This means that without job satisfaction POS can significantly influence OCB.
GAMBARAN KREATIVITAS GURU DALAM PENERAPAN KURIKULUM 2013 SEKOLAH DASAR DI SURABAYA
Authors: Sari Uni Kartika , Yoenanto Nono Hery
Published: February 2020

This research aims to determine teacher creativity in the 2013 curriculum implementation of elementary school in Surabaya. The teacher's creativity refers to Guilford's creativity (1967) that involves fluency of thinking, flexibility, originality and elaboration. Meanwhile, the Bronfenbrenner’s ecological system theory used as the grand theory. This research focuses on “X” and “Y” elementary schools. The instrumental case study took as design research, which used variant participants who interviewed by researcher such as teachers, principals and parents. This study uses a thematic analysis of data. Findings indicate that teacher creativity in the 2013 curriculum implementation have been carried out well where from fluency, flexibility and elaboration in planning of learning, process and evaluating learning outcomes of student. Meanwhile, the originality that related with the teacher's idea in planning learning still lacks authenticity. Furthermore, teacher also lack to creativity of assessment due to the thematic assessment content that depend respective educational units.
IDENTIFIKASI STRESS TERHADAP PERUBAHAN MELALUI PENGUKURAN KOGNITIF DAN RESPON HYPOTHALAMIC-PITUITARY-ADRENAL
Authors: Lufityanto Galang , Rahapsari Satwika , Kamal Isran
Published: February 2020

Lingkungan yang sarat dengan perubahan menuntut individu untuk senantiasa mampu beradaptasi dengan cepat. Kondisi stress muncul jika tuntutan untuk beradaptasi tidak sebanding dengan kapasitas yang dimiliki oleh individu tersebut. Salah satu cara untuk mendeteksi stress adalah dengan memberikan tes kognitif yang dilanjutkan dengan pengamatan respon hypothalamic-pituitary-adrenal (HPA) sebagai indikator fisiologis terhadap stress. Penelitian-penelitian terdahulu menggunakan Tes Kraepelin untuk menginduksi sekaligus meramalkan kapasitas individu dalam menghadapi stress. Namun demikian, literatur terbaru menunjukkan bahwa tes tersebut kurang prediktif karena kemungkinan adanya perbedaan individual. Penelitian kali ini melibatkan instrumen pengukuran kognitif numerik berbasis komputer yang memanfaatkan algoritme dinamis sehingga mampu menyajikan tingkat kesulitan yang sesuai dengan kapasitas maksimal tiap partisipan untuk mengatasi isu perbedaan individual ini. Penelitian ini menunjukkan bahwa kadar kortisol, sebagai hasil dari HPA, meningkat seiring dengan bertambahnya beban kognitif dalam tes kognitif numerik. Dengan demikian, temuan penelitian ini menunjukkan pentingnya penyesuaian tingkat kesulitas tugas terhadap kapasitas maksimal masing-masing individu untuk menghasilkan efek stress.
SOSIALISASI KEWIRAUSAHAAN SOSIAL DI PERGURUAN TINGGI ISLAM
Authors: Napsiah Napsiah
Published: February 2020

Abstrak Kewirausahan sosial di era 4.0 merupakan hal yang penting karena bertujuan bukan saja pada ekonomi tetapi juga ada nilai sosial yang dipertahankan. Untuk mencapai dua nilai tersebut, maka diperlukan media untuk mensosialisasikannya. Perguruan Tinggi menjadi relevan dalam hal ini, karena perguruan tinggi mencetak lulusan sarjana tiap tahunnya. Tulisan ini bertujuan menggambarkan aktivitas sosialisasi kewirausahaan di salah satu Perguruan Tinggi sebagi upaya merespons kewirausahan sosial melalui pendidikan.  Dengan menggunakan literatur dan pengalaman empirik tulisan menghasilkan kesimpulan bahwa menjadi wirausaha adalah implementasi tujuan dari Perguruan Tinggi Islam. Karena itu, melalui pendidikan kewirausahan mahasiswa disosialisasikan teori kewirausahaan dan praktik kewirausahan melalui program ekspose kewirausahan. Mahasiswa diberi kesempatan untuk mengembangkan program tersebut dengan mengacu pada sifat-sifat Nabi Muhammmad SAW seperti shidiq, amanah, fathonah, dan tabliq agar terbangun kerjasama antar civitas akademika dan mitra. Karena itu, Perguruan Tinggi Islam, sekalipun disiplin ilmu murni sangat relevan mencetak wirausahan sosial sesuai dengan tuntutan agama Islam.   Kata kunci: Kewirausahaan Sosial, Keinginan Berprestasi, Pemuda, Perguruan Tinggi Islam.
A simple method for amateur investors to analyze covered call options
Authors: Samsa Greg
Published: February 2020

We describe a simple method which amateur investors can use to analyze covered calls.  The most basic version is based on the formula for the expectation of a truncated Gaussian distribution, and it can be generalized to accommodate other assumptions.  This approach might be especially considered during a time of market overvaluation, such as the present.  During such times, investors should shift their preferences toward writing deep-in-the-money covered calls, which provide a greater margin of safety while monetizing the (probably optimistic) expectations of other market participants regarding future returns.
Organizing vocational education and training in schools: A case study of Australian Governments’ educational policies
Authors: CUI Guihua
Published: February 2020

Australian Governments of different levels have initiated and carried out some policies to reform vocational education and training in schools to ensure school to work successful transition. This article takes the New Framework as the target policy for analysis, supplemented by other related policies to investigate Governments’ purposes, principles and measures for organizing vocational education and training in schools. Dramaturgical coding method, together with excerpt-commentary analysis, has been adopted in the  policy analysis. It is found that the partnerships among different levels and different agencies are key to the organizational changes in the success of vocational education and training in schools in effecting a seamless work/study transition. This approach offers an  informed representation of the information that is conveyed in the New Framework by vividly interpreting its terms and conventions. The most important factor promoted by these policies was the promotion of partnerships between schools and industries.
SELEBRITY OF STUDENT ROLE IN CAMPUS
Authors: Zuhroh Ni’matuz , Wisadirana Darsono , Kanto Sanggar , Umanailo M Chairul Basrun , Mardiyono Mardiyono
Published: February 2020

Celebrity students, namely students whose duties besides studying at tertiary institutions also work as celebrities, among others as models, singers, endorsements, celebrities, etc. This study aims to find out how the role of celebrity students in Malang Brawijaya University, the causes and impacts. This study uses a qualitative phenomenological approach that is described descriptively with data sources consisting of University of Brawijaya University Malang celebrities. Data collection techniques in this study are observation, interviews, and documentation. The subject selection technique used was purposive sampling and snowball technique. The research subjects were 10 celebrity students from various faculties at Brawijaya University Malang. The validity of the data in this study uses source triangulation techniques, and data analysis uses Milles and Hubberman's interactive analysis. The results of this study indicate that the students of Celebrity Brawijaya University Malang. Students are not only expected to be able to contribute their knowledge to the community in the surrounding environment but also in the campus environment as an example of the students described above. From various student labels, in this study, students contribute to campus activities at. Celebrity students in this study play a role with Miss Universe Universitas Brawijaya, MC at campus events such as Graduation events, Dies Natalis etc., there are also those who come to the invitation on behalf of students outside the institution, there are also those who love, dance at every performance held on campus .
“Percepción de la Temperatura Climatológica en el Turismo y en Residentes de la Isla de Mallorca”
Authors: Torrens Calleja José M.ª
Published: February 2020

El presente artículo de percepción climatológica se basa en encuestas realizadas a turistas que han pernoctado en la Ciudad de Palma y han explorado la isla de Mallorca. Otros encuestados vinculantes han sido grupos de estudiantes de Geografía de Mallorca. Se interpretan los datos de percepción del turismo y población local. Al igual los datos de la serie climatológica del puerto y aeropuerto de la ciudad de Palma de Mallorca. La metodología se realiza con entrevistas personales dando a conocer su vinculación con el saber del clima que se percibe en Mallorca. Los resultados muestran dicha percepción que se puede ajustar o no a la realidad climatológica. El conocimiento de la isla se interpreta mediante preconceptos de la información meteorológica previa al realizar el viaje, por la experiencia en la isla y también por experiencia de visitas anteriores al territorio de Mallorca.
Is the policy environment for Zambia supportive of a thriving whole-of-government monitoring and evaluation system?
Authors: Kanyamuna Vincent
Published: February 2020

A whole-of-government monitoring and evaluation system (WoGM&ES) is a robust system that not only provides an integrated and all-encompassing framework of M&E practices, principles and standards to be used throughout government institutional structures, but also functions as an apex-level system for information and draws from the component systems in a framework meant to deliver essential M&E products tailored to satisfy information needs of users [1]. To implement a successful WoGM&ES, a supportive policy environment is crucial for any organisation, governments inclusive. The Zambian government is currently rolling out an ambitious WoGM&ES to strengthen its public sector accountability, feedback and learning functions. It was the objective of this study to investigate the policy environment in Zambia in respect of M&E practice in the public sector. In that regard, particular policy aspects were considered and these included assessing the availability of an M&E plan; whether the difference between M (monitoring) and E (evaluation) was recognised; and if the need for M&E autonomy and impartiality was mentioned. Others were to determine if feedback mechanisms were explicit as well as whether there was integration of M&E results in planning and budgeting processes. The study findings have shown that the policy environment to support a thriving M&E practice in the Zambian public sector was still fragmented and weak. While efforts by government to put policy measures were in place, evidence of transformational shift to implement these measures remained weak. However, it is promising that, in many ways, Zambia was on the right path regarding the introduction and articulation of policy provisions in support of M&E and broadly in promoting a culture of results.
Becoming a Complete Person : Discussing the Aim of Confucian Education
Authors: Ma Wen
Published: February 2020

The Confucian idea of humanness (Ren) is most commonly translated as “benevolence”. The aim of enhancing one’s virtue such as benevolence is to perform one’s occupation; to position oneself in the world; and to managing the state. Through teaching archery, charioteering(truth), rites(good), and poetry(beauty), the Confucian education aims at cultivate consummate individuals with complete characteristics. The application of Confucian education in the current early childhood education will be discussed.
AVRUPA YEREL YÖNETİMLER ÖZERKLİK ŞARTI
Authors: - -
Published: February 2020

Avrupa Konseyi üyesi Devletler tarafından Avrupa Yerel Yönetimler Özerklik Şartı aynen aktarılmıştır.