bluuebunny/crossref_metadata_2025 huggingface dataset:
Ultrafast colorimetric detection of Cr(vi) using Fe3O4@polydopamine/Prussian blue composites as a highly efficient peroxidase mimic
Authors: Xu Xianyuan , Guo Jingfang , Lei Zhen
Published: December 2022

An ultrafast and sensitive colorimetric method for detection of Cr(vi) was proposed based on the outstanding peroxidase-like activity of Fe3O4@polydopamine/Prussian blue composites.
Conjoined and non-conjoined coordination cages with palladium(ii) vertices: structural diversity, solution dynamics, and intermolecular interactions
Authors: Sharma Shruti , Sarkar Moumita , Chand Dillip Kumar
Published: December 2022

From classical single cavity cages to multicavity cages including high/low-symmetry versions are illustrated, also highlighting various dynamic aspects and intermolecular interactions.
Polymolybdate-guided assembly of a thiacalix[4]arene-protected Ag nanocluster for electrocatalytic CO2reduction
Authors: Li Shang-Qian , Dai Lin-Fang , Tian Yi-Qi , Yi Yi-Xiao , Yan Jun , Liu Chao
Published: December 2022

A polymolybdate-templated {Ag49Mo16} cluster stabilized by six thiacalix[4]arene ligands has been synthesized by a one-pot solvothermal reaction, which displays superior CO evolution activity for the electrocatalytic CO2reduction.
Water-mediated radical C–H tosylation of alkenes with tosyl cyanide
Authors: Hu Dongyan , Zhang Yang , Li Jianwei , Liang Kangjiang , Xia Chengfeng
Published: December 2022

A sulfinyl sulfone intermediate, generatedin situby the nucleophilic addition of water to tosyl cyanide, dominated the subsequent tosylation of alkenesviacascade di-radical addition/β-elimination.
Palladium-catalyzed generation of CO from formic acid for alkoxycarbonylation of internal alkenes involves a PTSA-assisted NH–Pd mechanism: a DFT mechanistic study
Authors: Li Jingjing , Wang Jinzhao
Published: December 2022

Extensive DFT calculations have been performed to find the mechanism of palladium-catalyzed alkyloxycarbonylation of an internal alkene with HCOOH, suggesting that the reaction preferably proceeds by a PTSA-assisted NH–Pd pathway.
Manipulation of N-heterocyclic carbene reactivity with practical oriented electric fields
Authors: Blyth Mitchell T. , Coote Michelle L.
Published: December 2022

Electric fields can be used to tune the nucleophilicity and electrophilicity of N-heterocyclic carbenes and enhance their catalytic activity.
Nucleophilic substitution reactions of microsolvated hydroperoxide anion HOO−(NH3)nwith methyl chloride and comparison between ammonia and water as the solvent
Authors: Hu Yang , Wu Xiangyu , Xie Jing
Published: December 2022

For a microsolvated HOO−(sol)n+ CH3Cl SN2 reaction, where sol = H2O or NH3, the barrier height is linearly correlated with the relative HOMO level of the microsolvated nucleophiles.
Guanidinium–amino acid hydrogen-bonding interactions in protein crystal structures: implications for guanidinium-induced protein denaturation
Authors: Negi Indu , Jangra Raman , Gharu Amit , Trant John F. , Sharma Purshotam
Published: December 2022

Structural analysis of guanidinium–amino acid interaction pairs in protein crystal structures is coupled with an effective scheme for classifying the optimized pairs, to gain understanding of the guanidinium:protein hydrogen bonding modes.
Treatment of emerging contaminants in simulated wastewaterviatandem photo-Fenton-like reaction and nutrient recovery
Authors: Silva Manoj , Eisa Mohamed , Ragauskaitė Dovilė , McMinn Madison H. , Tian Zhenyu , Williams Clinton , Knopf Allan , Zhang Lihua , Baltrusaitis Jonas
Published: December 2022

Nutrient rich wastewater containing emerging organic contaminants was used for struvite synthesis with a novel tandem process with a heterogeneous Fenton oxidation pretreatment.
Insight into the corrosion inhibition of the iron anode with electro-deposited polyaniline during the electrocoagulation treatment process of electroplating wastewater
Authors: Yu Jie , Liu Yunxiao , Wang Han , Yan Qun , Luo Jing
Published: December 2022

In this study, polyaniline (PANI) and polypyrrole (PPy) coatings were applied to modify iron plate anodes to treat electroplating wastewater by electrocoagulation (EC) treatment.
The greenhouse gas emissions from food consumption in Turkey: a regional analysis with developmental parameters
Authors: Bayram Hatice Merve , Ozturkcan Arda
Published: December 2022

Due to the expected growth rate in world energy consumption in the near future, it is critical to estimate future energy consumption and associated environmental problems as precisely as possible.
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB
Authors: Meng Zhuoqun , Lu Jianing , Ge Guangcai , Wang Guang , Zhang Ran , Li Yuhan , Guan Shuang , Lu Jing
Published: December 2022

Gs-Rb1 could alleviate HFD and PA-induced lipid accumulation by stimulating autophagic flux and inducing autophagic lipid degradation through the miR-128-TFEB pathway.
Alginate oligosaccharide ameliorates azithromycin-induced gut microbiota disorder via Bacteroides acidifaciens-FAHFAs and Bacteroides-TCA cycle axes
Authors: Yan Shuling , Zhu Yanhong , Li Lili , Qin Song , Yuan Jingyi , Chang Xiulian , Hu Shanliang
Published: December 2022

Alginate oligosaccharide and its compound improved intestinal microecological disorder caused by azithromycin and maintained metabolic homeostasis in mice via the Bacteroides acidifaciens–FAHFAs and Bacteroides–TCA cycle axes.
Diosgenin relieves oxaliplatin-induced pain by affecting TLR4/NF-κB inflammatory signaling and the gut microbiota
Authors: Man Shuli , Xie Lu , Liu Xuanshuo , Wang Genbei , Liu Changxiao , Gao Wenyuan
Published: December 2022

Diosgenin extracted from fenugreek, yam and other foods exhibits a wide range of pharmacological activities, especially for the treatment of pain and other nervous system diseases.
Dietary additive octyl and decyl glycerate modulates metabolism and inflammation under different dietary patterns with the contribution of the gut microbiota
Authors: Zhang Junhui , Yu Huilin , Wang Qianqian , Cai Haiying , Shen Fei , Ruan Shengyue , Wu Yue , Liu Tao , Feng Fengqin , Zhao Minjie
Published: December 2022

Octyl and decyl glycerate (ODG), a medium-chain triglyceride (MCT), is widely used as a food additive.
Bifidobacterium longum subsp. infantis FJSYZ1M3 ameliorates DSS-induced colitis by maintaining the intestinal barrier, regulating inflammatory cytokines, and modifying gut microbiota
Authors: Li Mingjie , Ding Jiuhong , Stanton Catherine , Ross R. Paul , Zhao Jianxin , Yang Bo , Chen Wei
Published: December 2022

B. longum subsp. infantis FJSYZ1M3 could significantly alleviate the symptoms of colitis by reducing the damage of the intestinal barrier, regulating the inflammatory cytokines, up-regulating butyric acid, and relieving gut microbiota disturbance.
Dietary leucine and fish oil cooperatively regulate skeletal myofiber type transformationviathe CaMKII signaling pathway of pigs
Authors: Gong Saiming , Yin Yunju , Han Mengmeng , Guo Liu , Duan Yehui , Guo Qiuping , Yin Jie , Li Fengna
Published: December 2022

The mechanism of dietary leucine and fish oil on skeletal myofiber type transformations in pigs.
Oxide ceramic electrolytes for all-solid-state lithium batteries – cost-cutting cell design and environmental impact
Authors: Schreiber Andrea , Rosen Melanie , Waetzig Katja , Nikolowski Kristian , Schiffmann Nikolas , Wiggers Hartmut , Küpers Michael , Fattakhova-Rohlfing Dina , Kuckshinrichs Wilhelm , Guillon Olivier , Finsterbusch Martin
Published: December 2022

An evaluation of the environmental impact of manufacturing an oxide all-solid-state lithium battery with economic cell design.
AC-driven multicolor electroluminescence from a hybrid WSe2 monolayer/AlGaInP quantum well light-emitting device
Authors: Chang Ya-Hui , Lin Yen-Shou , James Singh Konthoujam , Lin Hsiang-Ting , Chang Chiao-Yun , Chen Zheng-Zhe , Zhang Yu-Wei , Lin Shih-Yen , Kuo Hao-Chung , Shih Min-Hsiung
Published: December 2022

A multicolor AC-driven light-emitting device by integrating a WSe2 monolayer and AlGaInP–GaInP multiple quantum well (MQW) structures.
Cationic lipid modification of DNA tetrahedral nanocages enhances their cellular uptake
Authors: Singh Ramesh , Yadav Pankaj , Naveena A Hema , Bhatia Dhiraj
Published: December 2022

We present the functionalization of a model DNA cage, tetrahedron with a cationic lipid, DOTMA; demonstrating enhancement in cellular uptake of DNA nanocages by minimizing the negative charge and increasing hydrophobic surface mediated internalization.
Highly efficient and thermally stable broadband NIR phosphors by rationally bridging Cr3+–Yb3+ in LiScGe2O6 for optical bioimaging
Authors: Wang Chuanlong , Jin Yahong , Yuan Lifang , Wang Bo , Zhang Ruiting , Wu Haoyi , Yao Qing , Hu Yihua
Published: December 2022

A broadband NIR phosphor covering the 750–1200 nm region with high luminescence efficiency and good thermal stability was realized by the energy transfer of Cr3+ → Yb3+.
Colour-tuneable solid-state fluorescence of crystalline powders formed from push–pull substituted 2,5-diphenyl-stilbenes
Authors: Pauk Karel , Luňák Stanislav , Růžička Aleš , Marková Aneta , Teichmanová Kateřina , Mausová Anna , Kratochvíl Matouš , Smolka Rastislav , Mikysek Tomáš , Weiter Martin , Imramovský Aleš , Vala Martin
Published: December 2022

Polycrystalline powders of push–pull substituted stilbenes with various acceptors emit from blue to infrared. Exciton localization on a monomer (in J-like packing) or a stacked dimer (for H-aggregates) avoid exciton migration to the quenching sites.
New family of layered N-based cathode materials for sodium-ion batteries
Authors: Jiang Yundan , Xu Wangping , Zhao Wei , Cao Juexian
Published: December 2022

Layered 2H-phase CrN2 possesses many advantages including high capacity (335 mA h g−1), low diffusion barrier (0.49 eV), high voltage platform (3.8 V) and high energy density (1139 W h kg−1), which is a promising candidate for SIBs cathode materials.
Radiolabeled albumin through SNAr of cysteines as a potential pretargeting theranostic agent
Authors: Fischer Niklas H. , Lopes van den Broek Sara I. , Herth Matthias M. , Diness Frederik
Published: December 2022

Human serum albumin has been functionalized with a radionuclide by combining SNAr conjugation to Cys34 with CuAAC and inverse-electron demand Diels–Alder reactions demonstrating a promising strategy for generating theranostics by bioconjugation.
Preparation of high temperature NH3-SCR catalysts with carbonate as precursors by ball milling method
Authors: Wang Na , Wang Lei , Xie Huidong , Liu Yang , Sun Yepeng , Yang Chang , Ge Chengmin
Published: December 2022

High-temperature 10Ce–2La/TiO2 catalysts for selective catalytic reduction of NO with NH3 were prepared by the ball milling, impregnation and co-precipitation methods with different precursors and their catalytic performance was compared.
Preparation of VOC low-temperature oxidation catalysts with copper and iron binary metal oxides via hydrotalcite-like precursors
Authors: Zhang Hongwei , Li Jianjun , Shu Song , Guo Jiaxiu , Liu Yongjun , Cen Wanglai , Li Xinpeng , Yang Jianrong
Published: December 2022

Design diagram for the removal toluene by Cu–Fe catalyst prepared from precursor hydrotalcite.
Identification of four novel flavonoid adducts in Arabidopsis thaliana (L.) exposed to isobutyl S-2-diethylaminoethyl methylphosphonothiolate as potential plant exposure biomarkers
Authors: Xing Zhongfang , Zhang Ruiqian , Zhao Zhehui , Wang Liangliang , Yuan Ling , Yu Huilan , Yang Yang , Yang Yuntao , Liu Shilei , Pei Chengxin
Published: December 2022

Identification of flavonoid adducts in plants provides a novel strategy for the retrospective analysis of nerve agent exposure.
Fatty acid capped, metal oxo clusters as the smallest conceivable nanocrystal prototypes
Authors: Van den Eynden Dietger , Pokratath Rohan , Mathew Jikson Pulparayil , Goossens Eline , De Buysser Klaartje , De Roo Jonathan
Published: December 2022

Metal oxo clusters of the type M6O4(OH)4(OOCR)12 (M = Zr or Hf) are valuable building blocks for materials science.
Catalytic photochemical enantioselective α-alkylation with pyridinium salts
Authors: Yetra Santhivardhana Reddy , Schmitt Nathan , Tambar Uttam K.
Published: December 2022

We have developed a chiral amine catalyzed enantioselective α-alkylation of aldehydes with amino acid derived pyridinium salts as alkylating reagents.
Thermally activated delayed fluorescence emitters: a thionation approach toward next-generation photosensitizers
Authors: Wang Xiang , Wei Rao , Cai Lianjun , Hu Hai-Yu
Published: December 2022

Achieving highly efficient intersystem crossing (ISC) remains a key focus in the design of heavy atom-free photosensitizers (PSs) for various photophysical and photochemical applications.
Reversible human-temperature-responsive luminescence switching in a Mn(ii)-based metal halide
Authors: He Zi-Lin , Wei Jun-Hua , Luo Jian-Bin , Zhang Zhi-Zhong , Kuang Dai-Bin
Published: December 2022

The reversible phase transition with luminescence switching can be realized by simply laying hands on the (TMS)2MnBr4powder. Furthermore, it exhibits promising potentials in portable anti-counterfeiting, thermal imaging, and rewritable PL paper.
Sensory Inhibition and Speech Perception-in-Noise Performance in Children With Normal Hearing
Authors: Campbell Julia , Rouse Rixon , Nielsen Mashhood , Potter Sheri
Published: December 2022

Purpose:

This study investigated whether sensory inhibition in children may be associated with speech perception-in-noise performance. Additionally, gating networks associated with sensory inhibition were identified via standardized low-resolution brain electromagnetic tomography (sLORETA), and the detectability of the cortical auditory evoked potential (CAEP) N1 response was enhanced using a 4- to 30-Hz bandpass filter.

Method:

CAEP gating responses, reflective of inhibition, were evoked via click pairs and recorded using high-density electroencephalography in neurotypical 5- to 8-year-olds and 22- to 24-year-olds. Amplitude gating indices were calculated and correlated with speech perception in noise. Gating generators were estimated using sLORETA. A 4- to 30-Hz filter was applied to detect the N1 gating component.

Results:

Preliminary findings indicate children showed reduced gating, but there was a correlational trend between better speech perception and decreased N2 gating. Commensurate with decreased gating, children presented with incomplete compensatory gating networks. The 4- to 30-Hz filter identified the N1 response in a subset of children.

Conclusions:

There was a tenuous relationship between children's speech perception and sensory inhibition. This may suggest that sensory inhibition is only implicated in atypically poor speech perception. Finally, the 4- to 30-Hz filter settings are critical in N1 detectability.

Significance:

Gating may help evaluate reduced sensory inhibition in children with clinically poor speech perception using the appropriate methodology. Cortical gating generators in typically developing children are also newly identified.
Novel compact waveguide filtering twist for computer numerical control machining
Authors: Zhang Yi , Shang Xiaobang , Xu Jun , Guo Yuewei , Duan Lei , Lu Xiao
Published: December 2022

In this letter, the authors present a novel compact waveguide filtering twist that can be readily fabricated from metal using the computer numerical control (CNC) machining process. This filtering twist comprises four coupled resonators that are rotationally deformed to provide the desired 90° twist. Such resonator structures eliminate the use of curved features and therefore are ideally suitable for conventional CNC machining. The proposed design offers appealing advantages, including great compactness, easy fabrication, and good scalability to millimetre‐wave and terahertz frequencies. The design is demonstrated at X‐band and has a fourth‐order Chebyshev filter response (bandwidth 0.4 GHz, centred at 10 GHz). The good agreement between simulation and measurement results validates the proposed concept.
A novel high‐voltage solid‐state switch based on the SiC MOSFET series and its overcurrent protection
Authors: He Dazhao , Sun Wenjie , Liao Yixin , Zhang Penghao , Yu Liang , Dong Shoulong , Yao Chenguo , liu Xin
Published: December 2022

All‐solid‐state switches are one of the core components of pulsed power supply systems. However, the voltage level of a single switch is limited. By optimizing the chip structure, the voltage level of a single switch can be improved. Due to the immaturity of the production process and the positive correlation between the blocking voltage and the on‐resistance of the switch, it is difficult to improve the blocking voltage and the continuous forward current of a single switch simultaneously. The series‐connected switch is a way to increase the switch's blocking voltage without reducing the switch's continuous forward current. Magnetically coupled isolated drive and resistor‐capacitor forced voltage equalization techniques are investigated to increase the blocking voltage of the switches using multiple SiC metal‐oxide‐semiconductor field‐effect transistors (MOSFETs) in series connections. Meanwhile, a special overcurrent protection scheme is designed to improve the reliability of the series‐connected switch. Finally, a high‐voltage solid‐state switch is developed based on the SiC MOSFET series connections, whose output pulse width is adjustable from 20 to 300 μs, frequency is adjustable from 1 Hz to 3 kHz, the maximum output voltage can reach 57 kV (1 Hz), and the overcurrent protection time is about 1 μs.
Low‐carbon economic dispatch of the combined heat and power‐virtual power plants: A improved deep reinforcement learning‐based approach
Authors: Tan Yongqiang , Shen Yanxia , Yu Xinyan , Lu Xin
Published: December 2022

To realize the national strategies for carbon emission reduction, electric power industries should undergo reforms to cope with the multiple challenges of decarbonization, marketization, and energy transition. How to design a dispatch strategy that considers both low‐carbon demand and economic cost has become a major concern in integrated energy systems. To realize multi‐energy complementation and low‐carbonization, a scheduling framework of combined heat and power‐virtual power plants (CHP‐VPPs) considering carbon capture and power‐to‐gas is proposed. The stochastic dynamic optimization problem is modelled as a Markov decision process. An improved deep reinforcement learning‐based algorithm named multi‐level backtracking prioritized experience replay‐twin delayed deep deterministic policy gradient (MBEPR‐TD3) is employed to solve the low‐carbon economic dispatch problem. The results show that: (1) The profits have been increased by 85.8% and carbon emissions have been reduced by 30.3% because of the addition of power‐to‐gas in CHP‐VPP; (2) the revenues have been improved by 22.24% and carbon emissions have been decreased by 37.04% owing to the introduction of carbon capture and trading; (3) compared with results using DQN, DDPG, and TD3, the optimal dispatch strategy obtained by MBEPR‐TD3 has higher reward returns and more stable convergence.
Implementation of Hazard Analysis and Critical Control Point (HACCP) on Bread Bakery Production Process in Bunga Mawar Puti Bakery
Authors: Puspitawati Ika Nawang , Sunarti AR Yelvia , Saputro Erwan Adi , Suprihatin  , Edahwati Luluk , Wulandari Vika Dwi , Bibaroq Bayu Aji
Published: December 2022

This study aims to identify the hazards and potential that may arise at every stage of the bread production process in the Bakery by the HACCP system, analyzing the implementation of quality control and determining the CCP in the production process of bread at the bakery in Bunga Mawar Puti Bakery, Jatirejo, Mojokerto. The research was conducted using a survey method, by following the whole process of making bread bakery from the receiving raw materials to the packaging of the final product. The method of data analysis used was the descriptive analysis method. This research identifies results in the process of making sausage pizza bread, from raw materials to products that have the same dangers reviewed, including the physical, chemical, and biological. The results showed that CCP was found in 3 processes in the stage of the production process of sausage pizza bread. First, in the process of mixing bread dough, there is a chemical hazard caused by metal-contaminated materials. Second, the process of receiving cheese, sausage has biological hazards in the form of Escherichia coli bacteria. Third, the cooling process before packaging has physical hazards in the form of dust and dirt. The implementation of HACCP in Bunga Mawar Puti Bakery can help in fulfilling the quality requirements, increase consumer confidence and give the vigilance of occurrence of contamination.
Sea Cucumber Suppliers Selection Using Multi – Objective Optimization on The Basis of Ratio Analysis Methods
Authors: Cahyadi Indra , Novianti Trisita , Widiaswanti Ernaning , Ilhamsah Heri Awalul , Purwoko Sugeng , Hidayat Ananda Syalsabila
Published: December 2022

This study aims to implement decision making methodology to select raw material suppliers for sea cucumbers in fish cracker Micro, Small and Medium Enterprises (MSMEs) in Bangkalan Districts, Indonesia. Raw materials sourcing is one of the most critical functions in MSMEs because of its significant effect in reducing production costs and increasing overall profits. The sea cucumbers suppliers’ selection process is analysed in two phases. The first phase is the development of a hierarchy of problems in selecting fish cracker MSMEs suppliers to determine the selection criteria and sub-criteria. The Analytical Hierarchy Process (AHP) was used to determine pairwise comparisons, consistent weights and priority decisions of the alternative raw materials suppliers. In the second phase, Multi – Objective Optimization on The Basis of Ratio Analysis (MOORA) is conducted using the AHP results as input to optimize two or more conflicting objectives subject to some constraints. Then, the AHP method and the MOORA method were used to obtain the MSME’s sea cucumber suppliers ranking and evaluate the best possible suppliers.
The Physicochemical Properties of the Jelly Drink Produced by Mixing Pedada (Sonneratia caseolaris) and Young Coconut Juices with Carrageenan
Authors: Jariyah  , Rosida  , Defri Ifwarin , Wardani Pratiwi Eka Kusuma
Published: December 2022

This research was conducted to determine the physicochemical properties of the jelly drink produced using the pedada and young coconut fruit juices with carrageenan. A Completely Randomized Design was used with two factors consisting of pedada : young coconut juice ratio at 60:40, 70:30, and 80:20 as well as the addition of carrageenan at 0.25, 0.30, and 0.35% which are replicated twice with 5% of DMRT. The best mixture was 60:40 pedada to young coconut fruit juice with 0.35% carrageenan due to its ability to produce jelly drinks with a total acid content of 0.50%, antioxidant activity at 43.87%, total sugar at 19.00%, syneresis at 1.81%, gel strength at 1.16 N, and dietary fibre at 9.20%. Moreover, the organoleptic test showed the score of taste was 3.64, the texture was 3.64, the aroma was 3.20, and the colour was 3.76 and this generally means the drink was much flavoured by the panellists.
Experimental Study of Silty Soil Using Gypsum and Cement on California Bearing Ratio (CBR)
Authors: Budianto Eko , Utary Chitra , Hairulla  , Pamuttu Dina Limbong
Published: December 2022

Merauke Regency is a lowland area, with soft soil conditions that dominate and urgently need to be stabilized. The purpose of this study was to determine the use of a mixture of cement and gypsum as a stabilizing agent. This research uses laboratory experimental methods. The tests carried out are physical and mechanical properties testing. Laboratory CBR is used to determine the value of the increase in CBR on the original soil and soil that has been mixed with cement and gypsum variations. Based on the results of testing the physical properties of the grain fraction for silt of 85.88%, in the calcification using the AASHTO method this soil is included in group A-5 with a description of silt soil with high plasticity. From the results of the tests carried out the CBR value on silt soil is 2.62% while the CBR value of stabilized soil with a percentage of 100% silt + 2% cement + 4% gypsum is 23.54%; 100% silt + 2% cement + 8% gypsum that is 24.41%; 100% silt + 2% cement + 12% gypsum ie 27.02%; 100% silt + 2% cement + 16% gypsum ie 30.51%; and 100% silt + 2% cement + 20% gypsum that is 31.38%. From the CBR value, it can be concluded that the variation increased with each addition of cement and the percentage of gypsum.
The Design of Facial Expression Detection System to Determine the Level of Customer Satisfaction using K-Nearest Neighbor Method
Authors: Rahmawati Diana , Joni Koko , Maulana Muhammad Iqbal , Nahari Rosida Vivin , Ibadillah Achmad Fiqhi , Setiawan Heri , Saputro Adi Kurniawan
Published: December 2022

Facial expressions are one of the ways humans communicate to convey personal emotions to their communication partner nonverbally. Therefore, human facial expressions can be used for various purposes, one of which is knowing customer satisfaction. So far, customers of Bank Rakyat Indonesia (BRI) provide feedback on service quality using only a polling system, namely by filling out a criticism and suggestion form and then entering it in a suggestion box which is distinguished between satisfied and dissatisfied. However, such a method is less effective because it can be easily manipulated by customers and customers are often indifferent to the feedback. So that the improvement of service quality tends to be less effective. This research will design a system that can recognize human facial expressions to determine the level of customer satisfaction with input data in the form of video data taken by a webcam camera with the viola-jones method to detect faces and determine facial patterns. Then the facial data will be classified using the K-Nearest Neighbor method to determine the type of facial expression. Determination of the value of k will determine the success rate of facial expression detection. The processed data will be displayed on a liquid crystal display (LCD) and then stored in a MySQL database. The results showed that the accuracy of facial expression detection was 80.77% from 52 facial expression data.
Nonoperative Treatment of Single-Tendon Proximal Hamstring Avulsions
in Recreational Athletes
Authors: Bono Olivia J. , Forlizzi Julianne , Shah Sarav S , Nacca Christopher R. , Manz Eric , Ives Katharine , Miller Suzanne L.
Published: December 2022

The purpose of this study was to evaluate the patient-reported and objective
functional outcomes of those patients who underwent nonoperative management of a
single-tendon retracted proximal hamstring avulsion. A retrospective case series
of consecutive patients with an MRI-confirmed diagnosis of single-tendon
proximal hamstring avulsion treated nonoperatively with at least one year of
follow-up was performed. Patient-reported outcome measures (PROMs) including
SF-12v2, Lower Extremity Functional Score (LEFS), Hip Outcome Score-activities
of daily living and sport subscale (HOS-ADL, HOS-SS) were prospectively
collected. Objective measurements included strength testing of the affected and
unaffected limbs with a handheld dynamometer and single-leg hop test.
Student’s t-tests were used to determine differences between limbs.
Eleven of fourteen patients were available for PROMs (79%); five
completed functional testing. Subjective scores revealed a mean SF-12v2 mental
component score of 56.53±8.2, and a physical component score of
50.1±12.7. LEFS was 84%±19.8, HOS-ADL
87.9%±17.2, and HOS-SS 80.9%±24. The differences
between limbs were not statistically significant for strength at 45 or 90
degrees of knee flexion, nor for single-leg hop distance. Patients in a
non-professional athlete population who undergo nonoperative management of
single-tendon retracted proximal hamstring avulsions can expect good subjective
and objective outcomes.
It Is Not Only the Meniscus That Flips—A Case of TFCC Tear with a Flipped Fragment in the Distal Radioulnar Joint
Authors: Agarwal Aakanksha , Chandra Abhishek , Murray Timothy , Cresswell Mark
Published: December 2022

Acute wrist injuries with ongoing ulnar-sided wrist pain warrant a magnetic resonance imaging (MRI) to diagnose ligamentous injuries. Triangular fibrocartilage complex (TFCC) tears have been classified and described in the literature but complex tear patterns have limited representation. Bucket-handle tears of the TFCC represent only 0.5% of TFCC tears and have recently been identified, posing a diagnostic and management challenge. Preoperative diagnosis is possible with MRI and necessary for optimal and early surgical management. The authors describe a unique case of a flipped tear of the central disc of the TFCC, where the fragment was flipped into the distal radioulnar joint, a site hidden during routine arthroscopy.
What is it (like) to imagine an emotion?
Authors: Loev Slawa , Inchingolo Marco , Velasco Pablo Fernandez
Published: December 2022

What does it mean to imagine an emotion? The present article introduces a typology of three different ways in which it is possible to imagine emotion. This typology allows to individuate a form of imagining emotion that has been underexplored: emotion-like imagination. Emotion-like imagination, rather than being a way of merely imagining that a certain emotional experience occurs or a form of responding emotionally to imagined representations, requires a subject to re-enact the emotional state itself so that the imagining has emotional phenomenal properties as its main content. We go on to provide a first in-depth exploration of emotion-like imagination, suggesting emotion regulation mechanisms as the empirical grounds for its cognitive realizability. Finally, we sketch how emotion-like imagination can fruitfully complement discussions of affective forecasting and empathetic understanding.
Micromagnet design for addressable fast spin manipulations in a 2 × 2 quantum dot array
Authors: Nakamura Shungo , Kiyama Haruki , Oiwa Akira
Published: December 2022

The scaling up of semiconductor quantum dots to two-dimensional arrays is attracting considerable interest for use in large-scale spin-based quantum computation. One of the fundamental technologies to be realized in the two-dimensional arrays of quantum dots is the coherent manipulations of individual electron spins. In this work, we report on a micromagnet design that generates stray magnetic fields that can be used for spin manipulations via electric dipole spin resonance in a 2 × 2 quantum dot array. We consider a micromagnet with lower symmetry than that typically used in the case of linear dot arrays and optimize its dimensions to produce a maximum stray field gradient while maintaining Zeeman splitting differences sufficiently large among the four dots to permit qubit addressability. The optimized field gradient is around 60% smaller than that used in linear dot arrays, but it is still large enough for spin manipulation experiments. Our result represents an important step toward the experimental realization of spin-qubit operations in two-dimensional arrays of quantum dots.
Semi-Dirac and Dirac-node-arc phases in a (112) oriented Cd3As2 film
Authors: Liu Genhua , Lei Xuan
Published: December 2022

We investigate the electronic structure and spin-dependent densities of low-energy electron states in a (112) oriented Cd3As2 film. We find that the thick Cd3As2 film is a semi-Dirac material whose dispersion is linear (massless) in one direction and is quadratic (massive) in the orthogonal direction. Its spin-up and spin-down densities corresponding to linear dispersion, respectively, distribute at the top and bottom surface of the film, exhibiting the chirality of Dirac electrons, while the ones corresponding to quadratic dispersion overlap each other. In particular, an appropriate electric field vertical to the top surface of the film can result in anisotropic Rashba spin–orbit coupling and open a bandgap in the quadratic dispersions and its adjacent linear dispersions, driving a topological phase transition from a semi-Dirac-point phase to a Dirac-node-arc phase. Our findings predict a (112) oriented Cd3As2 film to be a candidate semi-Dirac material and provide a method to find Dirac-node-arc states for experiments.
Polyelectrolyte complexation of two oppositely charged symmetric polymers: A minimal theory
Authors: Mitra Soumik , Kundagrami Arindam
Published: December 2022

Interplay of Coulomb interaction energy, free ion entropy, and conformational elasticity is a fascinating aspect in polyelectrolytes (PEs). We develop a theory for complexation of two oppositely charged PEs, a process known to be the precursor to the formation of complex coacervates in PE solutions, to explore the underlying thermodynamics of complex formation, at low salts. The theory considers general degrees of solvent polarity and dielectricity within an implicit solvent model, incorporating a varying Coulomb strength. Explicit calculation of the free energy of complexation and its components indicates that the entropy of free counterions and salt ions and the Coulomb enthalpy of bound ion-pairs dictate the equilibrium of PE complexation. This helps decouple the self-consistent dependency of charge and size of the uncomplexed parts of the polyions, derive an analytical expression for charge, and evaluate the free energy components as functions of chain overlap. Complexation is observed to be driven by enthalpy gain at low Coulomb strengths, driven by entropy gain of released counterions but opposed by enthalpy loss due to reduction of ion-pairs at moderate Coulomb strengths, and progressively less favorable due to enthalpy loss at even higher Coulomb strengths. The total free energy of the system is found to decrease linearly with an overlap of chains. Thermodynamic predictions from our model are in good quantitative agreement with simulations in literature.
Aryl/aryl diazoalkanes in rhodium(II)-catalyzed rearrangements of sulfur ylides
Authors: Kloene Lennard , Jana Sripati , Empel Claire , Koenigs Rene M.
Published: December 2022

Sigmatropic rearrangement reactions are of prime interest in the construction of small complex molecules and find widespread application in drug discovery and natural product synthesis. Herein, we report on the application of aryl/aryl diazoalkanes in rhodium-catalyzed sigmatropic rearrangement reactions of allyl sulfides. Overall, a broad variety of different allyl sulfides and different aryl/aryl diazoalkanes were compatible and the desired products were obtained in high yield.
Managing emerging pathogen risks in recycled water
Authors: Short M. D. , van den Akker B. , Monis P. , Donner E.
Published: December 2022

The COVID-19 pandemic raised the public profile of wastewater-based infectious disease monitoring. General media coverage about wastewater detection of SARS-CoV-2 (the COVID-19 coronavirus) increased community awareness of the potential use of wastewater for the detection and surveillance of emerging diseases and also heightened recognition of the potential for wastewater to harbour and convey a variety of pathogens. This has also generated questions about the potential public health impacts of emerging pathogens, such as SARS-CoV-2 and mpox, in sewage and recycled water. To ensure water security in an era of climate change, water recycling is increasingly important in Australia and other water-stressed nations and managing disease risks in integrated water management is thus of critical importance. This paper demonstrates the existing risk management provisions for recycled water and explores potential issues posed by novel and emerging pathogens. First, a synopsis of some key emerging and re-emerging human pathogens is presented and the risks associated with these pathogens in the context of recycled water provision is considered. Then, an overview of the engineered treatment systems and regulatory framework used to manage these emerging risks in Australia is presented, together with a discusion of how emerging pathogen risks can be managed to ensure safe recycled water supply now and into the future.
PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells
Authors: Edwards Sarah C. , Hedley Ann , Hoevenaar Wilma H.M. , Wiesheu Robert , Glauner Teresa , Kilbey Anna , Shaw Robin , Boufea Katerina , Batada Nizar , Hatano Shinya , Yoshikai Yasunobu , Blyth Karen , Miller Crispin , Kirschner Kristina , Coffelt Seth B.
Published: December 2022

IL-17A–producing γδ T cells in mice consist primarily of Vγ6+ tissue-resident cells and Vγ4+ circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer remains poorly understood. Using single-cell RNA sequencing and flow cytommetry, we show that lung Vγ4+ and Vγ6+ cells from tumor-free and tumor-bearing mice express contrasting cell surface molecules as well as distinct co-inhibitory molecules, which function to suppress their expansion. Vγ6+ cells express constitutively high levels of PD-1, whereas Vγ4+ cells upregulate TIM-3 in response to tumor-derived IL-1β and IL-23. Inhibition of either PD-1 or TIM-3 in mammary tumor–bearing mice increased Vγ6+ and Vγ4+ cell numbers, respectively. We found that genetic deletion of γδ T cells elicits responsiveness to anti–PD-1 and anti–TIM-3 immunotherapy in a mammary tumor model that is refractory to T cell checkpoint inhibitors, indicating that IL-17A–producing γδ T cells instigate resistance to immunotherapy. Together, these data demonstrate how lung IL-17A–producing γδ T cell subsets are differentially controlled by PD-1 and TIM-3 in steady-state and cancer.
Layer-stacking of chalcogenide-terminated MXenes Ti2CT2(T = O, S, Se, Te) and their applications in metal-ion batteries
Authors: Nie Xiaomin , Ji Yujin , Ding Yi-min , Li Youyong
Published: December 2022

Owning to limited supply of lithium for Li-ion batteries, the development of non-Li-ion batteries (such as Na+, K+ Mg2+, Ca2+, and Al3+ ion batteries) has attracted significant research interest. In this work, by means of the first-principles calculations, we systematically investigated the performance of chalcogenide-terminated MXenes Ti2CT2 (T = O, S, Se, and Te) as electrodes for Li-ion and non-Li-ion batteries, as well as the layer-stacking and electronic properties of Ti2CT2. We find that the stacking type of O and Te terminated Ti2C multilayers with AA stacking differs from that of S and Se terminated Ti2C multilayers with AB stacking. More importantly, Ti2CO2 monolayer can be potential anode material for Na- and K-ion batteries with high capacities and very low diffusion barriers (0.03–0.11 eV), while Ti2CS2 and Ti2CSe2 are promising anode materials with relatively low average open circuit voltages (OCVs) for Na-, K-, and Ca-ion batteries (0.4–0.87 V). Among these materials, Ti2CS2 exhibits the largest ion capacity of 616 mAh g−1. These results of our work may inspire further studies of Ti2C-MXenes multilayers as electrodes for metal-ion batteries either experimentally or theoretically.
New cross-section measurements for the (n, 2n), (n, p), and (n, α) reactions on bromine in the 14 MeV region with detailed uncertainty quantification*
Authors: He Long , Luo Junhua , Jiang Li
Published: December 2022

Measurement of the cross-sections of the 79Br(n, 2n)78Br, 81Br(n, p)81mSe, 81Br(n, α)78As, and 79Br(n, α)76As reactions was performed at specific neutron energies, precisely, 13.5±0.2, 14.1±0.2, 14.4±0.2, and 14.8±0.2 MeV, relative to the standard 93Nb(n, 2n)92mNb and 27Al(n, α)24Na reference reactions using offline γ-ray spectrometry and neutron activation. Monoenergetic neutrons were generated at the China Academy of Engineering Physics via a 3H(d, n)4He reaction using the K-400 Neutron Generator equipped with a solid 3H-Ti based target. The activity of the reaction produce was obtained using a high-purity germanium detector. The cross-sections of the (n, 2n), (n, p), and (n, α) reactions on the bromine isotopes were measured in the 13–15 MeV neutron energy range. The covariance analysis approach was employed for a thorough inspection of any uncertainties within the measured cross-section data. A discussion and comparison of the observed outcome were carried out with previously published data, especially with the results of the JENDL-4.0, JEFF-3.3, TENDL-2019, and ENDF/B-VIII.0 data libraries, along with the theoretical excitation function curve derived by employing the TALYS-1.95 program. Improved cross-section restrictions for the investigated processes in the 13–15 MeV neutron energy range will be obtained using the current findings, which will help to raise the caliber of associated databases. Furthermore, the parameters of relevant nuclear reaction models can be verified using this data.
The interface stiffness and topographic feature dictate interfacial invasiveness of cancer spheroids
Authors: Mao Bin-Hsu , Nguyen Thi Kim Mai , Tang Ming-Jer , Kamm Roger D , Tu Ting-Yuan
Published: December 2022

During cancer metastasis, tumor cells likely navigate, in a collective manner, discrete tissue spaces comprising inherently heterogeneous extracellular matrix microstructures where interfaces may be frequently encountered. Studies have shown that cell migration modes can be determined by adaptation to mechanical/topographic cues from interfacial microenvironments. However, less attention has been paid to exploring the impact of interfacial mechnochemical attributes on invasive and metastatic behaviors of tumor aggregates. Here, we excogitated a collagen matrix-solid substrate interface platform to investigate the afore-stated interesting issue. Our data revealed that stiffer interfaces stimulated spheroid outgrowth by motivating detachment of single cells and boosting their motility and velocity. However, stronger interfacial adhesive strength between matrix and substrate led to the opposite outcomes. Besides, this interfacial parameter also affected the morphological switch between migration modes of the detached cells and their directionality. Mechanistically, myosin II-mediated cell contraction, compared to matrix metalloproteinases-driven collagen degradation, was shown to play a more crucial role in the invasive outgrowth of tumor spheroids in interfacial microenvironments. Thus, our findings highlight the importance of heterogeneous interfaces in addressing and combating cancer metastasis.
Extracellular-matrix-mimicked 3D nanofiber and hydrogel interpenetrated wound dressing with a dynamic autoimmune-derived healing regulation ability based on wound exudate
Authors: Gao Liheng , Liu Xingxing , Zhao Wenshuo , Li Chaojin , Wang Fujun , Gao Jing , Liao Xinqin , Wei Lei , Wu Hao , Zheng Yuanjin , Wang Lu
Published: December 2022

Dynamic regulation of wound physiological signals is the basis of wound healing. Conventional biomaterials delivering growth factors to drive wound healing leads to the passive repair of soft tissues because of the mismatch of wound healing stages. Meanwhile, the bioactivity of wound exudate is often restricted by oxidation and bacterial contamination. Herein, an extracellular matrix mimicked nanofiber/hydrogel interpenetrated network (NFHIN) was constructed with a 3D nanofibrous framework for cell immigration, and interfiled aerogel containing cross-linked hyaluronic acid and hyperbranched polyamidoamine to balance the wound microenvironment. The aerogel can collect wound exudate and transform into a polycationic hydrogel with contact-killing effects even against intracellular pathogens (bactericidal rate > 99.9% in 30 min) and real-time scavenging property of reactive oxygen species. After co-culturing with the NFHIN, the bioactivity of fibroblast in the ex vivo blister fluid was improved by 389.69%. The NFHIN showed sustainable exudate management with moisture–vapor transferring rate (6000 g m−2 ×24 h), equilibrium liquid content (75.3%), Young’s modulus (115.1 ± 7 kPa), and anti-tearing behavior similar to human skin. The NFHIN can collect and activate wound exudate, turning it from a clinical problem to an autoimmune-derived wound regulation system, showing potential for wound care in critical skin diseases.
Design of 3D-printed universal oral stent for tongue immobilization in head and neck radiotherapy
Authors: Mundee Thunpisit , Jongwannasiri Chavin , Fuangrod Todsaporn
Published: December 2022

The primary treatment for head and neck cancer is radiotherapy, which can cause complications and effects, such as the ability to speak, taste, produce saliva, and swallow. An oral stent is an immobilization tool for minimizing the dose in the tongue (or hard palate) by locking the tongue position during radiation delivery. It can improve the treatment accuracy due to less uncertainty caused by tongue position uncertainty between treatment fractions. However, commercial oral stents are not widely adopted in developing countries due to their unaffordable price. This study aimed to design the universal oral stent (UOS) to achieve high efficiency, ease to use, and low-cost fabrication based on 3D printing technology. There were five experiments to evaluate the UOS design and fabrication versus the modified cut syringe, including finite element analysis (FEA), the usability test, the micro Vickers hardness test, single beam dose analysis, and dose calculation on treatment plan simulations. The proposed UOS design and fabrication presented a high capability to apply for clinical use.
The automated measurement of CT number linearity using an ACR accreditation phantom
Authors: Anam Choirul , Amilia Riska , Naufal Ariij , Budi Wahyu S , Maya Anisa T , Dougherty Geoff
Published: December 2022

We developed a software to automatically measure the linearity between the CT numbers and densities of objects using an ACR 464 CT phantom, and investigated the CT number linearity of 16 different CT scanners. The software included a segmentation-rotation method. After segmenting five objects within the phantom image, the software computed the mean CT number of each object and plotted a graph between the CT numbers and densities of the objects. Linear regression and coefficients of regression, R2, were automatically calculated. The software was used to investigate the CT number linearity of 16 CT scanners from Toshiba, Siemens, Hitachi, and GE installed at 16 hospitals in Indonesia. The linearity of the CT number obtained on most of the scanners showed a strong linear correlation (R
2 > 0.99) between the CT numbers and densities of the five phantom materials. Two scanners (Siemens Emotion 16) had the strongest linear correlation with R
2 = 0.999, and two Hitachi Eclos scanners had the weakest linear correlation with R
2 < 0.99.