bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of Viral Inactivation Protocols for Therapeutic Blood Products against Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
Authors: Belem Wendimi Fatimata , Liu Ching-Hsuan , Hu Yee-Tung , Burnouf Thierry , Lin Liang-Tzung
Published: November 2022

Therapeutic blood products including convalescent plasma/serum and immunoglobulins concentrated from convalescent plasma, such as intravenous immunoglobulins or hyperimmune globulins, and monoclonal antibodies are passive immunotherapy options for novel coronavirus disease 2019 (COVID-19). They have been shown to improve the clinical status and biological and radiological parameters in some groups of COVID-19 patients. However, blood products are still potential sources of virus transmission in recipients. The use of pathogen reduction technology (PRT) should increase the safety of the products. The purpose of this study was to determine the impact of solvent/detergents (S/D) procedures on SARS-CoV-2 infectivity elimination in the plasma of donors but also on COVID-19 convalescent serum (CCS) capacity to neutralize SARS-CoV-2 infectivity. In this investigation, S/D treatment for all experiments was performed at a shortened process time (30 min). We first evaluated the impact of S/D treatments (1% TnBP/1% TritonX-45 and 1% TnBP/1% TritonX-100) on the inactivation of SARS-CoV-2 pseudoparticles (SARS-CoV-2pp)-spiked human plasma followed by S/D agent removal using a Sep-Pak Plus C18 cartridge. Both treatments were able to completely inactivate SARS-CoV-2pp infectivity to an undetectable level. Moreover, the neutralizing activity of CCS against SARS-CoV-2pp was preserved after S/D treatments. Our data suggested that viral inactivation methods using such S/D treatments could be useful in the implementation of viral inactivation/elimination processes of therapeutic blood products against SARS-CoV-2.
European Brown Hare Syndrome in Poland: Current Epidemiological Situation
Authors: Fitzner Andrzej , Niedbalski Wiesław , Kęsy Andrzej , Rataj Bogusław , Flis Marian
Published: November 2022

European brown hare syndrome (EBHS) is one of the main causes of mortality in brown hares (Lepus europaeus) and mountain hares (Lepus timidus) in Europe. Since the mid-1990s, this highly lethal and contagious plague has been widespread in many European countries, contributing to a drastic decline in the number of free-living and farmed hares. A second lagovirus, able to infect some species of hares is rabbit haemorrhagic disease virus 2 (RHDV2; GI.2) recognised in 2010, a new viral emergence of RHDV (GI.1) which is known to be responsible for haemorrhagic disease in rabbits—RHD. The aim of this study was to evaluate the current EBHS epidemiological situation on the basis of the presence of antibodies to European brown hare syndrome virus (EBHSV) and anti-RHDV2 antibodies in sera collected from free-ranging hares in Central and Southeastern Poland in 2020–2021. Additionally, studies on the presence of EBHSV and RHDV2 antigens or their genetic material in the blood and internal organs taken from brown hares between 2014–2021 have been carried out. The results of the serological examination showed nearly 88% of tested blood samples were positive for EBHSV antibodies. No EBHSV was identified in the examined hares using virological and molecular tests. The positive results of EBHS serological studies confirmed the circulation and maintenance of EBHSV in free-living brown hares in Poland. However, no serological, virological or molecular evidence was obtained indicating that the brown hares tested had been in contact with RHDV2.
Experimental Investigations on Influence of Fracture Networks on Overland Flow and Water Infiltration in Soil
Authors: You Jin , Wang Shuqian , Xu Dan
Published: November 2022

Soil preferential flow is an essential process that affects the movement and relocation of soil water and solutes. This study was conducted on cropland in an arid and semi-arid area in Zhongning County, Ningxia. According to the different cracks, rain intensity, rainfall duration, and slope, there were three groups, and 17 dye tracer experiments were conducted in the field. We quantified the characteristics of soil preferential flow by investigating and analyzing the infiltration depth, dyeing area, saturation, runoff coefficient, and rainfall infiltration coefficient using the dye tracer method. The results showed that increasing the rainfall or irrigation intensity could promote the activation of the fracture channel as the preferential flow channel, which is advantageous to the preferential flow formation. The fractures dominated the formation of the preferential flow. The fractures slowed the formation of runoff, reduced the velocity of slope flow, reduced the flow of the slope, and increased the amount of soil water infiltration. These results have theoretical and practical significance for understanding soil water transportation, especially for agricultural irrigation management and improving cropland water use efficiency in arid and semi-arid areas.
Comprehensive Evaluation on Urban Water Security Based on the Novel DPEBLR Concept Model and the Cloud Matter-Element Model: A Case Study of Chongqing, China
Authors: Deng Hongwei , Song Xiaojie , Li Changshun , Li Yanyan , Diao Hu , Xu Jingbo
Published: November 2022

Urban water security problems such as water scarcity, water pollution, and flood disasters have restricted the sustainable development of cities. In order to scientifically evaluate the urban water security situation, this study combined the DPSIR (driver, pressure, state, impact, response) model and HEVD (the hazard of disaster-causing factors, the vulnerability of disaster-affected bodies, the instability of the disaster-pregnant environment, and population loss) model to propose a new conceptual framework for DPEBLR (driver, pressure, environment, insecurity-affected body, loss, response). Based on this conceptual framework, 35 indicators were selected to establish an urban water security evaluation index system. In order to solve the problem of randomness and fuzziness of the boundary values of urban water security classification levels, the cloud matter element model was applied. Chongqing was used as an example for verification, and the results showed that the water security status of Chongqing City improved from 2011 (Ⅴ) to 2019 (Ⅱ). This indicates that the water ecology restoration project, centralized water source protection project, centralized water supply project, water-saving society transformation, and flood and drought prevention system construction project implemented in Chongqing has achieved significant results. However, Chongqing still faces the problem that the construction of an urban flood control system cannot meet the speed of urban development. The government should slow down the urbanization and allow the urban flood control system to be ready before the area is occupied. In addition, the awareness of water conservation for industrial use in Chongqing has been formed, and citizens’ awareness of water conservation for domestic use should be enhanced in the future.
Fe3O4 Nanoparticles Loaded Bentonite/Sawdust Interface for the Removal of Methylene Blue: Insights into Adsorption Performance and Mechanism via Experiments and Theoretical Calculations
Authors: Barakat Mohamed A. , Kumar Rajeev , Halawani Riyadh F. , Al-Mur Bandar A. , Seliem Moaaz K.
Published: November 2022

Herein, magnetite nanoparticles (MNPs) synthesized from altered basalt were used to develop a composite with H2O2–activated bentonite (BE) and fibrous sawdust (SD). The as-prepared BE/SD–MNPs were characterized by FTIR, FESEM, TEM, TGA, DSC, and Zeta potential techniques and utilized as an effective multifunctional composite for removing methylene blue (MB). The adsorption isotherms of MB at 25–55 °C were analyzed via kinetics, classical, and advanced statistical physics models. Theoretically, the pseudo-second-order of kinetics and the Freundlich isotherms model fit the experimental data well without microscopically clarifying the adsorption mechanism. Studying a multilayer model’s steric and energetic parameters was a reliable approach to understanding the MB uptake mechanism at the molecular scale. Sterically, the removed MB molecules offered a combination of horizontal and vertical geometry (i.e., mixed orientation). The MB adsorption capacity at saturation (Qsat) increased from 829 to 849 mg/g with temperature, suggesting endothermic interactions. Energetically, the MB uptake by BE/SD–MNPs was controlled by physical interactions (i.e., adsorption energy < 20 kJ/mol). The BE/SD–MNPs retained more than 85% of the MB uptake after five adsorption-desorption rounds. Overall, this study aimed to understand the MB adsorption mechanism using a magnetic clays/lignocellulosic interface such as the utilized BE/SD–MNPs composite as a promising strategy in wastewater remediation.
Multilayer Feedforward Artificial Neural Network Model to Forecast Florida Bay Salinity with Climate Change
Authors: Abiy Anteneh Z. , Wiederholt Ruscena P. , Lagerwall Gareth L. , Melesse Assefa M. , Davis Stephen E.
Published: November 2022

Florida Bay is a large, subtropical estuary whose salinity varies from yearly and seasonal changes in rainfall and freshwater inflows. Water management changes during the 20th century led to a long-term reduction in inflows that increased mean salinity, and the frequency and severity of hypersalinity. Climate change may exacerbate salinity conditions in Florida Bay; however, future salinity conditions have not been adequately evaluated. Here, we employed a Multilayer Feedforward Artificial Neural Network model to develop baseline salinity models for nearshore and offshore sites. Then, we examined the impacts of climate change on salinity using forecasted changes in various input variables under two climate change scenarios, representative concentration pathways (RCP) 4.5 and 8.5. Salinity could rise by 30% and 70% under the RCP4.5 and RCP8.5 forecasts, respectively. Climate change affected nearshore salinity significantly more, which rapidly fluctuated between mesohaline (5 to 18 PSU) and metahaline (40 to 55 PSU) to hypersaline conditions (>55 PSU). Offshore salinities ranged between euhaline (30 to 40 PSU) to metahaline (40 to 55 PSU) conditions. Our study suggests that increased freshwater flow would help maintain suitable estuarine conditions in Florida Bay during climate change, while our novel modeling approach can guide further Everglades restoration efforts.
Study on Ecological Compensation of Inter-Basin Water Transfer Based on Evolutionary Game Theory
Authors: Peng Zhuoyue , Pu Hangrong , Liang Yubin
Published: November 2022

Ecological compensation for inter-basin water transfer is an effective way of coordinating regional ecological environment protection and balancing the interest relationship between the water-source area and the water-receiving area. However, there are still some deficiencies in the research on the evolutionary game analysis and the compensation behavior of stakeholders. To this end, a replication dynamic model of evolutionary game analysis was established to analyze the behavior and mutual influence of the governments of the water-source area and the water-receiving area. We examined the dynamic evolution process of each strategy, discussed the stability of the evolution result, and calculated the penalty amount of the superior supervision department through the market value method and the willingness-to-pay method. The results show that in the process of independent selection of local governments, the social optimal environmental protection strategy (protection, compensation) will not reach a balanced and stable state, and the constraint elements of the superior supervision department must be introduced. If the penalty amount is greater than the maximum value between the wealth lost in the water-source area due to ecological protection and the money the local residents in the water-receiving area is willing to pay, the optimal stability strategy can be achieved most easily. Taking Yangzhou, the water-source area of the east route of the South-to-North Water Transfer Project, and Jinan, the water-receiving area, as an example, it is calculated that the loss cost of Yangzhou is 1.304 billion RMB (USD 189 million), and Jinan is willing to pay 1.753 billion RMB (USD 254 million). Therefore, in order to stabilize the optimal strategy (protection, compensation) between the governments of Yangzhou and Jinan, the penalty amount of the superior supervision department should be greater than 1.753 billion RMB (USD 254 million). Our results could provide a reference for regulating the relationship between stakeholders and promoting the innovation of ecological compensation system for inter-basin water transfer.
Cu(II) Adsorption from Aqueous Solution onto Poly(Acrylic Acid/Chestnut Shell Pigment) Hydrogel
Authors: Zhang Hui , Li Guo-Wei , Feng Wei , Yao Zeng-Yu
Published: November 2022

Powerful adsorbents for heavy-metal removal from wastewater are attractive due to the growing effluent of industries. Developing hydrogels is a current research interest in heavy-metal adsorption from aqueous solutions. We prepared a novel melanin-based hydrogel from renewable chestnut shell pigment and acrylic acid by radical polymerization free from a traditional crosslinker. The synthesized material was characterized by Fourier transform infrared spectroscopy and scanning electron microscope. Its Cu(II)-adsorption performance from the water was evaluated by equilibrium isotherms, kinetics, and thermodynamics. The results indicate that: (1) The dry hydrogel showed a porous structure with a network of interconnected spindle-shaped bars, which makes it feasible to serve as an adsorbent; (2) The kinetic adsorption data followed both the pseudo-first-order and the pseudo-second-order models and both physical and chemical processes involved in the Cu(II) removal; (3) Cation exchanges with H+ from COOH and phenolic OH groups and with NH4+ from –COONH4 were likely the primary mechanisms of Cu(II) chemisorption adsorption onto the poly(AA/CSP) as forms of Cu2+ and CuOH+; (4) The equilibrium data were well fitted by the Langmuir isotherm with the maximum monolayer adsorption capacity of 200.3 mg/g; (5) The adsorption was a spontaneous and exothermic process co-driven by enthalpy and entropy.
PENERAPAN SISTEM ENTERPRISE RESOURCE PLANNING (ERP) PADA PERUSAHAAN JASA KONSTRUKSI
Authors: Indrayani Ni Luh Ayu
Published: November 2022

Pembangunan infrastruktur di Indonesia merupakan salah satu hal yang paling diperhatikan oleh pemerintah saat ini. Dalam melaksanakan proyek kontruksi perlu dilakukan manajemen sumber daya proyek. Sumber daya proyek konstruksi terdiri dari beberapa jenis diantaranya biaya, waktu, sumber daya manusia, material, dan juga peralatan yang digunakan dalam pelaksanaan proyek, dimana dalam mengoperasionalkan sumber daya-sumber daya tersebut perlu dilakukan dalam suatu sistem manajemen yang baik, sehingga dapat dimanfaatkan secara optimal. Sistem Enterprise Resources Planning (ERP) atau sistem aplikasi terintegrasi merupakan sistem informasi yang digunakan untuk mengintegrasikan dan mengotomatisasikan proses bisnis dalam manajemen perusahaan secara transparasi dan memiliki akuntabilitas yang cukup tinggi. Dengan adanya sistem yang terintegrasi tersebut maka setiap unit fungsional dalam suatu perusahaan dapat saling berbagi data dan informasi yang pada akhirnya meningkatkan sinergi antar elemen di perusahaan yang menerapkannya. Penelitian ini dilakukan dengan tujuan untuk mengetahui penerapan Sistem Enterprise Resources Planning (ERP) pada perusahaan jasa konstruksi di Indonesia dengan melakukan studi literatur, baik berupa artikel dan jurnal ilmiah. Berdasarkan penelitian yang telah dilakukan maka dapat disimpulkan bahwa dengan perusahaan menerapkan sistem software ERP untuk industri konstruksinya, perusahaan tersebut akan dapat mengelola biaya proyek dan keseluruhan proyek dengan mudah. Kegiatan operasional bisa sepenuhnya dilakukan secara otomatis termasuk semua tahap proses konstruksi dan pembuatan laporan secara real-time. Dengan modul-modul utama yang ada pada sistem ERP maka akan semakin memudahkan dalam mendukung kegiatan konstruksi pada perusahaan dalam rangka melakukan perkembangan industri jasa konstruksi kedepannya.
SPESIFIKASI FASILITAS PEJALAN KAKI DI JALAN ASIA-AFRIKA KOTA BANDUNG
Authors: Pane Ricky Kurniawan
Published: November 2022

Fasilitas pejalan kaki adalah semua prasarana dan sarana yang disediakan bagi pejalan kaki untuk menjamin kelancaran, keamanan, kenyamanan, serta keselamatan pejalan kaki. Jalan Asia-Afrika adalah salah satu jalan yang ada di kota Bandung yang memiliki kegiatan aktivitas dari pejalan kaki. Kegiatan banyak dilakukan di sana karena adanya kawasan perkantoran, kawasan wisata, dan lain sebagainya. Penelitian ini menghitung volume pejalan kaki, volume kendaraan, dan volume penyeberang pada jalan. Penelitian juga melihat bagaimana kondisi eksisting geometri dari fasilitas pejalan kaki yang ada pada jalan Asia-Afrika. Kemudian memperkirakan lebar efektif dan jenis penyeberangan yang dapat digunakan. Penelitian ini berfokus pada Pedoman Perencanaan Fasilitas Pejalan Kaki PUPR. Fasilitas pejalan kaki pada jalan Asia-Afrika dibagi menjadi 3 segmen. Segmen I didapat hasil tidak ditemukannya tempat sampah dan sisi Utaranya tidak ditemukan tempat duduk Segmen II didapat volume tertinggi pejalan kaki sebesar 367 orang pada sisi Utara dan 243 orang untuk sisi Selatan, penyeberangan tertinggi 475 orang dengan 7134 kendaraan yang melintas, dengan kondisi eksisting yang sangat memenuhi. Segmen 3 tidak memiliki tempat duduk, tempat sampah dan bolar. Beberapa fasilitas yang diatur pada pedoman tidak dapat ditemukan dan tidak sesuai dengan yang ada pada setiap segmen trotoar. Hasil leber efektif segmen II didapat 12m untuk sisi Utara dan 8,4m untuk sisi Selatan, lebar ini tidak sesuai dengan ditemukan pada lapangan, sisi Utara 7m dana sisi selatan 6,6m. Penyeberangan yang digunakan ialah jenis pelican karena volume tertinggi penyeberang 475 orang dan 6861 kendaraan yang melintas.
PENGARUH PENAMBAHAN SODIUM GLUCONATE TERHADAP WAKTU PENGIKATAN, KELECAKAN DAN KUAT TEKAN BETON MUTU 20 MPA
Authors: Mukti Fuji Wibowo
Published: November 2022

Bahan pemanis merupakan salah satu bahan yang berfungsi untuk memperlambat pengerasan suatu beton. Sodium gluconate merupakan bahan pemanis yang digunakan pada penelitian ini. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh penambahan sodium gluconate terhadap kelecakan, waktu pengikatan dan kuat tekan beton. Pada penelitian ini digunakan mutu beton 20 MPa dengan variasi kadar penambahan sodium gluconate sebanyak 0%, 0.15%, 0.30% dan 0.45% dari berat semen. Dari pengujian yang telah dilakukan didapatkan hasil bahwa sodium gluconate dapat memnepengaruhi campuran beton. Pada pengujian kelecakan, sodium gluconate dapat membuat campuran agregat menjadi lebih mudah dikerjakan, kemudian pada pengujian waktu pengikatan beton normal membutuhkan waktu 528 menit, sedangkan dengan tambahan kadar sodium gluconate 0,15% selama 655 menit, 0,30% selama 2023 menit dan 0,45% selama 3450 menit dan pada pengujian kuat tekan beton dengan tambahan bahan sodium gluconate 0.15% dapat mengurangi nilai kuat tekan sebanyak 20,91% , tetapi pada variasi 0.30% dan 0.45% dapat menaikkan nilai kuat tekan beton sebanyak 12,80% dan 58,71%.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUTUSAN KONSUMEN E-COMMERCE MENGGUNAKAN DIGITAL ACCUMULATED BALANCE PAYMENT SYSTEM (PAY LATER)
Authors: Jaya* Rama Chandra , Triono Sunu Puguh Hayu
Published: November 2022

Penelitian ini berisi kajian mengenai gambaran dan pengaruh dari faktor-faktor yang mempengaruhi keputusan konsumen menggunakan Accumulated Balance Payment System atau Paylater. Penelitian ini mengunakan metode deskripstif dan kuantitatif dengan analisis menggunakan Structural Equation Modeling dan software SmartPLS. Sumber data yakni primer dan sekunder yang bersumber dari online maupun offline. Hasil pengujian hipotesis menunjukkan variabel Demographics, Orientations, Psychographics berpengaruh positif dan signifikan terhadap Consumer Consumer Payment Technology Use Decission Decission. Berdasarkan hasil penelitian pentingnya peranan keluarga terdekat seperti orang tua, suami atau istri dalam pemberian izin untuk mengunakan Paylater dalam berbelanja menggunakan Paylater. Perusahaan perlu melakukan penerapan Familly Sharing Payment System dalam akun Paylater. Hal ini diharapkan akan memberikan kemudahan pembayaran dan jangkauan pengguna yang lebih banyak, memberikan solusi bagi anggota keluarga yang belum bekerja, memberikan pembatasan kredit serta kemudahan pembayaran yang terintegrasi dalam satu akun utama.

Kata Kunci: Bayar nanti, Teknologi Pembayaran, Akumulasi Saldo, Berbagi Pembayaran, Keputusan Konsumen
KUALITAS PRODUK DAN HARGA SERTA DAMPAKNYA TERHADAP KEPUTUSAN PEMBELIAN
Authors: Ridwanudin* Riki , Oktafani Farah
Published: November 2022

Penelitian ini dilakukan untuk mengetahui pengaruh kualitas produk dan harga terhadap keputusan pembelian Samsung Galaxy S20 Series di Indonesia. Tujuan dilakukannya penelitian ini adalah untuk mengetahui dan menganalisis bagaimana presepsi konsumen terhadap  kualitas produk, bagaimana keputusan pembelian Samsung Galaxy S20 Series, besarnya pengaruh kualitas produk dan harga secara simultan dan  parsial terhadap keputusan pembelian Samsung Galaxy S20 Series di Indonesia. Berdasarkan uji hipotesis secara simutan, kualitas produk dan harga berpengaruh signifikan terhadap keputusan pembelian Samsung Galaxy S20 Series. Berdasarkan hasil uji hipotesis secara parsial (uji t) didapat bahwa variabel  kualitas produk dan  harga berpengaruh signifikan terhadap keputusan pembelian Samsung Galaxy S20 Series di Indonesia. Berdasarkan koefisien determinasi simultan didapat bahwa kualitas produk dan harga dapat mempengaruhi keputusan pembelian sebesar 52,9% dan sisanya 47,1% dipengaruhi oleh faktor-faktor lain yang tidak diteliti dalam peneliti ini.

Kata Kunci: Harga, Keputusan Pembelian, Kualitas Produk, Bauran Pemasaran, Pemasaran
PENGARUH IKLIM KETERLIBATAN ORGANISASI DAN KETERLIBATAN KARYAWAN TERHADAP KINERJA ORGANISASI SEKTOR INDUSTRI MANUFAKTUR INDONESIA
Authors: Sutopoh* Sutopoh , Machmud Fajar , Rahayu Agus , Wibowo Lili Adi
Published: November 2022

Organisasi semakin bergantung pada penciptaan pengetahuan dan pengembangan manusia untuk pertumbuhan yang optimal dan berkelanjutan. Keterlibatan karyawan adalah konstruksi utama yang menyentuh hampir semua aspek manajemen sumber daya manusia seperti yang kita kenal sekarang. Tujuan penelitian ini adalah untuk menguji pengaruh iklim organisasi terhadap keterlibatan karyawan pada sektor industri manufaktur yang berlokasi di Kawasan Industri Karawang, Jawa Barat, Indonesia. Populasi dalam penelitian ini adalah Perusahaan Manufaktur di Kawasan Industri Karawang Indonesia. Responden yang dimaksud adalah Manajer atau Supervisor di perusahaan dengan jumlah 75 responden. Teknik analisis yang digunakan dalam penelitian ini adalah partial least square (PLS-SEM). Hasil penelitian ini menunjukkan bahwa terdapat pengaruh positif dan signifikan kedua variabel yang diteliti terhadap Kinerja Organisasi.

Kata Kunci: Iklim Keterlibatan Organisasi, Keterlibatan Karyawan, Kinerja Organisasi, Sektor Industri Manufaktur, Karawang
Cutaneous Leishmaniasis Analyses in an Endemic Focus in Southwest Iran (2016-2020)
Authors: Chenani-Rahimi Kobra , Maleki Mehdi , Behbahani Abdolamir
Published: November 2022

Background: The cutaneous type of leishmaniasis (CL) has widespread growth. This research was conducted to explore the epidemiological characteristics of CL in the county of Shush in the Khuzestan Province located in the southwestern region of Iran. Methods: This cross-sectional study was retrospectively conducted from 2016 to 2020. Patients’ demographics and medical history were acquired to some extent. The recorded data of patients with CL referred to Shush health centers were analyzed using the SPSS software (Chicago, IL). Results: Overall, 2020 patients were recorded from 2016 to 2020. Among Shush residents, the incidence of CL ranged from 126.2 to 285.8 cases per 100000 people. The results demonstrated a statistically significant difference in the number of people who got CL in Shush county (P<0.05). Based on the results, a statistically significant correlation was found between CL and gender (including 54.7% males against 45.3% females, P<0.05). CL was found in more significant numbers in the age groups under ten years old (42.6%) compared to the other age groups (P<0.05). Conclusion: Shush seems to be a CL endemic hotspot based on the results of this research and other epidemiological parameters. The intensity of CL reports from this study and other epidemiological studies suggests that CL is more prevalent in Shush than in previous. The situation is extremely alarming; thus, it is highly recommended that adequate measures be taken to control and prevent the spread of illness.
The Comparative Effect of Definitive Chemoradiotherapy and Neoadjuvant Chemoradiotherapy Plus Surgery on One-Year Survival Rate of Esophageal Cancer Patients
Authors: Khanaki Fatemeh , Karimi Moghaddam Zhaleh , Chehre Hossein , Kamali Koorosh , Saghatchi Faranak , Rezaeejam Hamed
Published: November 2022

Background: Esophageal cancer is a malignancy with a poor survival rate, and the optimal management of esophageal cancer patients is still controversial. This study aimed to compare the one-year survival of patients who had received definitive chemoradiotherapy (DCRT) or neoadjuvant chemoradiotherapy plus surgery (NCRT+S). Materials and Methods: In this cross-sectional descriptive study, the medical records of esophageal cancer were extracted from 2018 to 2019; the last survival status of patients was obtained one year after the end of the treatment course. Data were analyzed using SPSS (version 16), and survival was estimated by the Kaplan-Meier method with the log-rank test. A P value of less than 0.05 was considered significant for all the performed tests. Results: Among 43 eligible patients, 39.5% were males and 60.5% were females. The mean age of the patients was 68.16±12.03 years. In this population, 81.4% of cases had squamous cell carcinoma (SCC), and the rest had adenocarcinoma (ADC). In addition, 58.1% and 41.9% of cases were treated by DCRT and NCRT+S, respectively. The one-year survival rate was 68% and 66.67% in the DCRT and NCRT+S groups, respectively (P>0.05). The one-year survival rate did not have significant relevance to the age of patients and histologic subtype. In terms of gender, there was no significant difference between males and females regarding the one-year survival rate. Conclusion: There were no statistically significant differences in the one-year survival rate of the patients in the two treatment groups; thus, further studies are recommended to confirm the results.
Extracorporeal Shock Wave Lithotripsy Success Rate and Prognostic Factors
Authors: Saburi Ehsan , Arab Fatemeh , Razi Abdolah
Published: November 2022

Background: Urinary tract stones are common urological problems with a considerable burden worldwide. Management strategies mostly rely on the stone’s characteristics and the patient’s clinical conditions. Extracorporeal shock wave lithotripsy (ESWL) is a method of choice for managing small calculus. However, the success rate of ESWL and the prognostic factor of success widely vary among different studies. The aim of the present study was to evaluate these prognostic factors in an Iranian population undergoing ESWL. Methods: The present retrospective study was conducted in Imam Ali Hospital of Bojnurd, Iran. Every patient who was referred for the ESWL of distal urethral calculus (5-20 mm) and failed to respond to medical treatment enrolled in this study. The prevalence and relationship between various individual factors and ESWL outcomes were evaluated among the study patients. Results: Among 49 patients (24 males and 25 females) who had urinary tract stones, the mean (±standard deviation) of age was 42.7 (14.04) years. ESWL could successfully treat urinary tract stones in 43 patients (85%). The kidney stone diameter was not related to having a successful procedure (P=0.447). Moreover, the stroke number and receiving tamsulosin were not significantly associated with favorable ESWL outcomes (P=0.909 and P=0.590, respectively). Twenty-seven patients (45.1%) received pethidine during the procedure. There was a significant relationship between receiving analgesics and favorable ESWL outcomes (P=0.033). Conclusion: The results demonstrated that 85% of the distal urinary tract stones that are smaller than 20 mm can be successfully managed by ESWL, and providing analgesics was significantly related to better outcomes.
Effect of nanocurcumin on serum levels of betatrophin and irisin in patients with metabolic syndrome; a clinical trial
Authors: Gholami Hamid , Kheiripour Nejat , Bahmani Mehdi , Ranjbar Akram , Khodamoradi Zahra , Borzouei Shiva
Published: November 2022

Introduction: Metabolic syndrome is a highly prevalent disease with combination of cardio metabolic risk factors. Insulin resistance is the most important reason of metabolic syndrome. Objectives: The study aimed to evaluate the effects of nanocurcumin on insulin resistance and serum level irisin and betatrophin in patients with metabolic syndrome. Patients and Methods: Sixty metabolic syndrome patients (30 males and 30 females) received 80 mg/daily nanocurcumin for three months. The samples of fasting blood were collected at the beginning of the study and after 90-days intervention to measure the biomarkers. Results: comparing pre and post treatment with nanocurcumin values revealed a significant change in fasting plasma glucose (FPG), fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and irisin (P>0.05), but there was no change in the amount of betatrophin (P>0.05). Conclusion: According to the results, it seems that the use of nanocurcumin for 90 days may have positive effects on some metabolic components. However, more studies with larger sample sizes are needed to confirm the findings. Trial registration: The trial protocol was approved by the Iranian Registry of Clinical Trials (identifier: IRCT20120215009014N214; https:// www.irct.ir/trial/30187, ethical code; IR.UMSHA.REC.1396.859).
Comparison of the effect of polyethylene glycol 40% and fig syrups on the treatment of chronic functional constipation in children: A randomized clinical trial
Authors: Maleki Narges , Kasiri Karamali , Malek-Ahmadi Mohammad Reza , Deris Fatemeh
Published: November 2022

Background and aims: None of the available constipation treatments for children are completely successful. Therefore, the present study aimed to evaluate the effect of the polyethylene glycol (PEG) solution 40% and fig syrup on the treatment of chronic constipation in children. Methods: In this double-blind clinical trial, 120 patients with chronic functional constipation were selected and divided into two groups. The first group received 5 mL of fig syrup without senna 3 times daily, and the second group took PEG 40% syrup at 1 mL/kg of body weight per day (the dose was adjustable according to the patient’s condition and need). At weeks 0, 2, 4, and 6, a checklist containing questions about children’s constipation was completed by the researcher, and the data were analyzed by SPSS version 24. Results: Changes in the frequency of abdominal pain at fourth times 0, 2, 4, and 6 weeks demonstrated statistically significant differences between the two groups (P=0.044), and it was significantly lower the in PEG group; however, the defecation was not statistically significant (P=0.902). After six weeks, the frequency of painful defecation, difficult defecation straining during defecation, and fear of defecation was significantly lower in the group given PEG syrup compared to the fig syrup-receiving group (P=0.001). Conclusion: Overall, PEG syrup was significantly effective in treating chronic functional constipation in children compared to the fig syrup.
Investigation of the effect of early and late breast milk enrichment on growth parameters in preterm infants: A randomized clinical trial
Authors: Hamidi Majid , Asadpour Nabiollah , Choopani Roya
Published: November 2022

Background and aims: This study aimed to investigate and compare the effect of early and late breast milk fortification on growth parameters in preterm infants. Methods: In this clinical trial, 90 preterm infants (28-32 weeks) admitted to the neonatal intensive care unit (NICU) of Hajar Hospital in Shahrekord, Iran were randomly divided into three groups. The fortification was performed when the milk intake reached 30 (group A), 70 (group B), and 100 cc/kg (group C). The height, weight, and head circumference of newborns were measured at the beginning of birth and 4 weeks after the birth. The incidence of sepsis and necrotizing enterocolitis, and milk tolerance were investigated as well. All analyses were conducted with Stata software, and P values<0.05 were considered statistically significant. Results: The value changes in the height, weight, and head circumference in all three groups at 4 weeks were significant (P<0.001). The mean weight changes in the A, B, and C groups were 727.33±163.85, 947.33±155.38, and 808.66±168.82, indicating a statistically significant difference (P<0.001). Further, the mean change of weight after 4 weeks showed statistically significant differences (P<0.001) among the A, B, and C groups. The weight gain in the B group was significantly higher than that of the A and C groups (P<0.05); however, no significant difference was observed in the mean weight gain between the A and C groups (P=0.264). Conclusion: The breast milk fortification when the milk intake reached 70 cc/kg had better efficiency on neonatal weight gain compared with the early and delayed fortification.
The relationship between mental health and perceived social support with the post traumatic growth model through the mediating role of coping strategies in COVID-19 recovered patients
Authors: Deldadeh Mehraban Elnaz , Farhangi Abdolhassan , Abolghasemi Shahnam
Published: November 2022

Background and aims: Post-traumatic growth refers to the positive psychological changes experienced after an incident. Coronavirus disease 2019 (COVID-19) is seen as a traumatic incident that impacts many aspects of a person's life. The present study aimed to investigate the association between perceived social support and mental health with the post-traumatic growth model through the mediating role of coping strategies in COVID-19 recovered patients. Methods: This study was conducted using a path analysis method from the correlation matrix. The research population included all COVID-19 recovered patients in Golestan Province. Using the convenience sampling method, 300 patients who recovered from COVID-19 were selected. The research instruments included the Post-Traumatic Growth Inventory, the General Health Questionnaire, the Multidimensional Scale of Perceived Social Support, and the Ways of Coping Questionnaire. The data was analyzed through structural equation modeling (SEM) using SPSS and AMOS software version 25. Results: The findings revealed that the suggested model fit the data. The relationship between post-traumatic growth, perceived social support, and mental health with problem-focused coping strategies were positive and significant (P<0.01). The relations between mental health and perceived social support with post-traumatic growth were positive and significant. Post-traumatic growth and perceived social support had a negative and significant relationship with emotion-focused strategies (P<0.01). Furthermore, the relationship between mental health and emotion-focused strategies was not significant. Conclusion: Mental health, perceived social support, and problem-focused strategies play an essential role in COVID-19 patients' post-traumatic growth. As a result, they might be helpful in minimizing the psychological impact of COVID-19.
Relationship between Exposure to Hookah Smoke and Lung Capacity of Hookah Cafe Employees
Authors: Alipour Vali , Eshaghi Hadi , Rezaei Leila , Ghanbarnejad Amin , Hosseini Zahra , Ghaffari Hamid Reza , Dehghani Somayyeh
Published: November 2022

Background: The aim of the present study was to investigate the effect of exposure to hookah smoke on the respiratory capacity of employees working in hookah cafes in Bandar Abbas. Methods: A total of 75 employees of hookah cafes and 64 people in the control group were the target population. Participants without a history of smoking, diabetes, and hypertension were included in the study. First, the height and weight of subjects were measured and then a respiratory test was performed by an occupational medicine specialist. At the same time, a checklist was completed, which contained demographic characteristics, history of working in hookah cafes, pulmonary diseases, hypertension, smoking, exercising, and a second job. Results: The mean age of the case and control groups was found to be 31.41 and 30.73 years, respectively. The mean values of the indices in the case and the control groups were as follows: forced expiratory volume (FEV1): 84.4% and 89.9%, forced vital capacity (FVC): 91.5% and 91.1%, forced expiratory flow 25-75 (FEF25-75): 78.7% and 75.9%, and peak expiratory flow (PEF): 87.2% and 95.2%, respectively. A significant relationship was found between exposure to hookah smoke and the lung capacity of employees working in hookah cafes (P <0.001). Conclusion: Based on the findings of the study and in order to reduce passive exposure to hookah smoke and its negative consequences, officials should review and apply strict rules on hookah use and monitor and control the air quality inside hookah cafes.
GEOMETRIC MORPHOMETRIC BANANA LEAF MIDRIB AS WIND TURBINE AIRFOIL PROFILE
Authors: Rosa Firlya , Sutikno Priyono , Suweca I Wayan , Moelyadi Mochammad Agoes
Published: November 2022

Profil airfoil merupakan salah satu faktor yang mempengaruhi kinerja turbin angin sumbu horizontal. Sejumlah penelitian telah mengadopsi bentuk dan gerak binatang baik binatang air maupun binatang yang terbang. Anatomi alami pelepah daun pisang menjadi salah satu inspirasi untuk pemodelan profil airfoil. Profil pelepah dari tujuh sampel daun pisang dipetakan dengan menggunakan teknik morfometri geometrik berbasis landmark. Analisis sampel menggunakan metode statistik dan analisis aerodinamis airfoil menggunakan perangkat lunak QBLADE dengan perubahan bilangan Reynolds mulai dari 3E5 hingga 7E5 pada interval 1E5. Ada tujuh sampel dengan variasi profil dan variasi aerodinamis yang konstan. Dari hasil penelitian didapatkan bahwa semua model memiliki koefisien angkat tinggi, koefisien hambat rendah, dan glide ratio tinggi. Sampel 1 pada bilangan Reynolds 7E5 memiliki glide ratio tertinggi dengan nilai 123,07. Dari hasil analisa aerodinamis didapatkan bahwa dalam kondisi kecepatan angin rendah, profil airfoil berdasarkan morfologi pelepah pisang dapat diterima untuk turbin angin.
Klasifikasi dan Penugasan Manpower untuk Pengkalibrasian Alat Laboratorium Industri menggunakan Metode Naive Bayes
Authors: Paduloh Paduloh , Widyantoro Murwan , Nabilatusolihah N
Published: November 2022

Perusahaan jasa pengkalibrasian alat-alat industri yang berlokasi didaerah Bekasi mengalami sebuah permasalahan, dimana terdapat beberapa complain dari customer dikarenakan terdapat delay dalam pengerjaan. Tujuan dari penelitian ini adalah untuk menemukan pembagian penugasan manpower secara merata antara laboratorium dan onsite, dimana dilakukan pegnklasifikasian dengan menggunakan Naive Bayes. Berdasarkan analisa klasifikasi aktual persentase pembagian manpowernya yaitu 51% untuk penempatan laboratorium dan 49% untuk pengerjaan onsite tanpa melihat dari persentase kompetensi personilnya. Setelah dilakukan rearrangement dengan menggunakan Naive Bayes dan Rapidminer, hasil pembagiannya berubah menjadi 56% untuk laboratorium dan 44% untuk onsite dimana diklasifikasi ulang berdasarkan nilai persentase kompetensi personilnya. Untuk personil dengan kompetensi diatas 82% diutamakan untuk melakukan kegiatan onsite. Dampak yang dihasilkan setelah adanya rearrangement ini yaitu terjadi perubahan dalam pembagian tugas dan alat customer menjadi cepat terkalibrasi
El uso de nuevas tecnologías como perspectiva para una universidad competitiva
Authors: Gámez de Mosquera Alicia
Published: November 2022

Se plantea la necesidad de redimensionar a la Universidad sobre paradigmas tecnológicos, sustentada en la pertinencia y excelencia para hacerla competitiva, y para que ofrezca respuestas a las perspectivas del desarrollo social a través del cumplimiento de sus funciones: Docencia, Investigación, Extensión, de la cooperación académica, y de la transferencia de conocimientos a la producción; sujeta a un proceso de evaluación constante. Se trata de una Universidad: extendida refractada, multifacética, plural, vinculada a la sociedad, con infraestructuras de telemática que fortalezcan la educación a distancia, y que apoye los roles compartidos del profesor y del estudiante como mediadores del conocimiento, en una educación permanente, sin lindeles.
ANALISIS BAGI HASIL BRILINK DAN JENIS PERJANJIAN BRILINK DALAM MEKANISME LAYANAN KEUANGAN TANPA KANTOR ( Studi kasus di Desa Sukasari dan Desa Gandasari Kecamatan Kadupandak)
Authors: Yulianti Devi , Suwiryo Darmo H
Published: November 2022

Tujuan dari penelitian ini adalah untuk mengetahui sistem bagi hasil agen BRILink di Desa Sukasari dan Desa Gandasari Kecamatan Kadupandak Kabupaten Cianjur dalam Mekanisme Officeless Financial Service. Penelitian ini merupakan penelitian dengan menggunakan metode deskriptif kualitatif. Teknik pengumpulan data yang digunakan adalah observasi, wawancara dan dokumentasi. Kemudian dari data yang diperoleh dianalisis dan dibahas untuk menjawab permasalahan penelitian ini. Hasil penelitian ini menunjukkan bahwa Sistem Bagi Hasil Agen BRILink menggunakan sistem Sharing Fee. Biaya agen BRILink di Desa Sukasari dan Desa Gandas Kecamatan Kadupandak Kabupaten Cianjur merupakan sistem bagi hasil atau fee jasa antara BRI dengan agen BRILink dengan prosentase fee 50%:50%. 50% untuk agen dan 50% untuk BRI. Jenis Perjanjian Agen BRILink dalam agen BRILink dan perjanjian kerjasama BRI memuat pengertian agen BRILink, ruang lingkup perjanjian, wilayah operasional Agen BRILink, Jangka Waktu Kerjasama, Layanan Agen, Hak dan kewajiban Agen BRILink, hak-hak dan kewajiban Bank, kegiatan yang dilarang dan sanksi. hukum, pembayaran, klasifikasi Agen BRILink, Kerahasiaan, pemeriksaan, pembatasan transaksi, penyelesaian sengketa, keadaan memaksa, lain-lain, pemutusan perjanjian. Analisis Bagi Hasil BRILink dan Jenis Perjanjian BRILink pada Mekanisme Officeless Financial Services di Desa Sukasari dan Desa Gandasari Kecamatan Kadupandak Kabupaten Cianjur sudah sesuai dengan unsur pelayanan yaitu unsur tugas pelayanan, sistem atau prosedur pelayanan, kegiatan pelayanan, pelayanan pelaksana.
PENGARUH PENGENDALIAN INTERNAL, GOOD UNIVERSITY GOVERNANCE, DAN PENGGUNAAN TEKNOLOGI INFORMASI, TERHADAP KINERJA PERGURUAN TINGGI
Authors: Indarti Indarti , Apriliyani Ika Berty , Aljufri Aljufri
Published: November 2022

Untuk mencapai apa yang menjadi tujuan dari perguruan tinggi dapat dilihat dari tingkat kinerja perguruan tinggi tersebut. Salah satu aspek penting yang menjadi tolak ukur keberhasilan perguruan tinggi dewasa ini adalah good university governance¸ suatu sistem yang berfungsi untuk mengarahkan dan mengendalikan organisasi. Selain dari penerapan prinsip-prinsip GUG di perguruan tinggi untuk pencapaian kinerja perguruan tinggi yang lebih baik dan efektif, salah satu cara yang diperlukan adalah penggunaa teknologi informasi.Pemanfaatan dari teknologi informasi itu sendiri bertujuan untuk meningkatkan kinerja karyawan yang ada di lingkungan PT. Perguruan Tinggi. Pengendlian Internal yang baik diharapkan akan meningkatkan kinerja Perguruan Tinggi. Penelitian ini dilakukan untuk melihat apakah Good University Governance (GUG), penggunaan teknologi informasi, dan pengendalian Internal berpengaruh  terhadap kinerja perguruan tinggi yang ada di Propinsi Riau. Metode yang digunakan adalah penelitian kuantitatif. Teknik analisis data yang digunakan dalam penelitian ini adalah uji regresi linier berganda. Dimana sebelum melakukan uji regresi terlebih dahulu melakukan analisis asumsi klasik yang terdiri dari 1) uji normalitas, 2) uji multikolinieritas, 3) uji heteroskedastisitas, dan 4) uji autokorelasi. Setelah dilakukan uji asumsi klasik langkah berikutnya adalah uji hipotesis dengan mengggunakan persamaan 1) uji parsial (uji t), 2) uji F dan 3) uji Determinasi. Hasil Penelitian ini adalah Pengendalian Internal dan Pemanfaatan Teknologi Informasi berpengaruh terhadap Kinerja Perguruan tinggi, sedangkan Good University Governance tidak berpengaruh terhadap Kinerja Perguruan tinggi
PENGARUH PEMANFAATAN TEKNOLOGI DAN MODERNISASI SISTEM ADMINISTRASI PERPAJAKAN TERHADAP KEPATUHAN WAJIB PAJAK ORANG PRIBADI (Studi Kasus Pada WPOP yang Terdaftar di KPP Mikro Piloting Majalengka)
Authors: Magribi Robi Maulana , Yulianti Desi
Published: November 2022

Tingkat kepatuhan Wajib Pajak Orang Pribadi masih rendah terbukti dengan masih banyaknya wajib pajak terdaftar yang tidak patuh dalam melaporkan perpajakannya, khususnya dalam modernisasi sistem admnistrasi perpajakan dan masih banyak juga Wajib Pajak Orang Pribadi yang kurang melek teknologi yang mengakibatkan masih kurangnya  pengetahuan Wajib Pajak untuk bisa lebih memanfaatkan teknologi yang ada, sehingga tingkat kepatuhan Wajib Pajak Orang Pribadi dalam hal ini masih harus lebih ditingkatkan. Penelitian ini untuk mengetahui bagaimana pengaruh pemanfaatan teknologi dan modernisasi sistem administrasi perpajakan terhadap kepatuhan Wajib Pajak Orang Pribadi pada Kantor Pelayanan Pajak Mikro Piloting Majalengka secara parisial. Variabel dependen dalam penelitian ini yaitu Kepatuhan Wajib Pajak Orang Pribadi dan variabel independen dalam penelitian ini adalah pemanfaatan teknologi dan modernisasi sistem administrasi perpajakan. Penelitian ini dilakukan di KPP Mikro Piloting Majalengka, jumlah sampel yang diambil dalam penelitian ini yaitu sebanyak 141 orang teknik pengambilan sampel yang digunakan adalah Nonprobability sampling  teknik sampling yang digunakan yaitu Incidental sampling, metode yang digunakan dalam penelitian ini adalah metode survey. Jenis penelitian ini kuantitatif dengan metode analisis deskriptif dan verifikatif. Analisis verifikatif terdiri dari uji asumsi klasik, analisis regresi linear berganda, dan koefisien determinasi. Hasil penelitian ini menunjukan bahwa secara parsial pemanfaatan teknologi pemanfaatan teknologi tidak berpengaruh terhadap kepatuhan Wajib Pajak Orang Pribadi dan modernisasi sistem administrasi perpajakan berpengaruh signifikan terhadap kepatuhan Wajib Pajak Orang Pribadi.