bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN LKS INTERAKTIF SCIENCE LIVE WORKSHEET BERBASIS HOTS SISWA SEKOLAH DASAR
Authors: Sari Nursina , Haifaturrahmah Haifaturrahmah , Ratu Tursina , Widiartini Ni Nengah , Erfan Muhammad
Published: December 2022

Abstrak: Lembar Kerja Siswa (LKS) merupakan salah satu media ajar yang harus dikembangkan oleh pendidik dalam upaya menunjang pelaksanaan kegiatan belajar mengajar terutama mata pelajaran yang memiliki muatan IPA. Tujuan penelitian ini untuk mengetahui: (1) Kevalidan, (2) Kepraktisan, serta (3) Keefektifan dari produk LKS interaktif Science’s live worksheet berbasis HOTS  dalam pembelajaran siswa di Sekolah Dasar (SD). Jenis penelitian ini adalah R&D (Research & Development) dengan mengadaptasi model dari Borg & Gall, dan menggunakan desain kelas one group pretes- posttest design. Adapun hasil pengembangan dari LKS interaktif Science’s live worksheet berbasis HOTS  menunjukkan hasil bahwa (1) Kevalidan dari produk LKS interaktif Science’s live worksheet berbasis HOTS   berhasil dikembangkan  persentase kevalidan produk sebesar sebesar 96,67%%,  yang termasuk dalam kategori “Sangat Valid” (2) Kepraktisan dari produk LKS interaktif Science’s live worksheet berbasis HOTS  dengan hasil rata-rata 98% di kategori “sangat praktis, (3) Keefektifan dari LKS interaktif Science’s live worksheet berbasis HOTS  dengan besarnya n-gain skor memperoleh 0,7 yang termasuk dalam kategori tinggi. Dengan demikian, LKS interaktif science’s liveworksheets yang dikembangkan valid, praktis, dan efektif digunakan dalam pembelajaran sains di sekolah dasar.Abstract:  Student Worksheet (LKS) is one of the teaching media that must be developed by educators in an effort to support the implementation of teaching and learning activities, especially subjects that have science content. The purpose of this study was to determine: (1) Validity, (2) Practicality, and (3) Effectiveness of the HOTS-based interactive Science's liveworksheet in student learning in elementary schools. This type of research is R&D (Research & Development) by adapting the model from Borg & Gall, and using a one-group pretest-posttest design. The results of the development of the HOTS-based interactive Science's live worksheet shows that (1) The validity of the HOTS-based Science's live worksheet interactive product has been successfully developed, the percentage of product validity is 96.67%%, which is included in the "Very Valid" category (2 ) The practicality of the HOTS-based interactive Science's live worksheet with an average result of 98% in the “very practical” category, (3) The effectiveness of the HOTS-based Science's live worksheet with an average n-gain score of 0.7 is included high in the HOTS category. Thus, the interactive science's live worksheets developed are valid, practical, and effective for use in science learning in elementary schools.
ELEVATED H2/N2 SEPARATION PERFORMANCE BY ANNEALING POST-TREATMENT OF POLYSULFONE HOLLOW FIBER MEMBRANE
Authors: Caralin I.S. , Widyanto A.R. , N. Widiastuti  , R. Wijiyanti  , T. Gunawan  , Karim Z.A. , M. Nomura  , Y. Yoshida
Published: December 2022

This study aims to enhance the H2/N2 separation performance of polysulfone (PSF) hollow fiber membranes by annealing. X-ray diffraction, SEM, and FESEM were utilized to evaluate morphological and structural changes in denser annealed PSF membranes. AFM topography images were used to investigate the annealed form and roughness of PSF membranes. Before testing membrane permeation, it was annealed at 120, 150, and 190 °C to optimize gas separation performance. Compare to all annealing temperatures (120, 150, and 190 °C), the annealed PSF membrane at 150 °C had the greatest H2/N2 selectivity (16.18), but its separation performance was unsatisfactory since it was below the Robeson upper limit curve. The PSF before annealing and the PSF annealed at 190 °C showed outstanding separation performance (2.60 and 2.71, respectively), despite their lower selectivity than the PSF annealed at 150 °C
CHEMICAL FINGERPRINTING OF PIPERINE AND TANNIC ACID IN AN AYURVEDIC FORMULATION OF DASANAKANTHI CHURNAM USING RP-HPLC
Authors: Sam Srija , Md Isha Ali Syeda Alisha , Muddukrishna B. S. , Vasantharaju S. G.
Published: December 2022

Dental diseases are one of the significant public health problems globally. Herbal medicines for managing oral diseases are considered an effective alternative to synthetic compounds due to their lower side effect. Acacia catechu, Piper nigrum, Piper longum, and Piper cubeba are vital components of Dasanakanthi Churnam used to control and prevent oral inflammations in dentistry. Tannic acid and Piperine are major markers for the chemical fingerprinting of Dasanakanthi Churnam. They serve as quality indicating parameters for Dasanakanthi Churnam because of their pharmacological action. Development and validation of a stability-indicating assay method using RP-HPLC become an integral part of simultaneous estimation of Tannic acid and Piperine in Dasanakanthi Churnam. Stability indicating the method is established by exposing markers to various stress conditions such as alkaline hydrolysis, photolytic, oxidative and thermal conditions. Stress testing of the markers can help identify the likely degradation products and validate the stability indicating the power of the analytical procedures used. Tannic acid and Piperine were effectively separated at 5.2 and 22.5 minutes respectively using a PDA detector without interference from any degradant and impurities. This research gives a scope to further carry out the stability studies such as accelerated, intermediate, and long-term studies for Dasanakanthi Churnam.
A NOVEL RIVAROXABAN DEGRADATION IMPURITY DETECTION BY RP-HPLC, EXTRACTION BY PREPARATORY CHROMATOGRAPHY, AND CHARACTERIZATION BY LCMS, NMR, AND FT-IR: ANALYSIS OF NOVEL IMPURITY IN BATCH SAMPLES AND TABLETS OF RIVAROXABAN
Authors: Bhupatiraju Rajesh Varma , Sreenivasa Rao Battula , Venkata Narayana Rao Kapavarapu Maruthi , Varaprasad Reddy Mandapati
Published: December 2022

A novel rivaroxaban degradant was obtained at 0.45% w/w level during the “RP-HPLC” analysis in the acetic acidexposed rivaroxaban sample. This novel rivaroxaban degradant has a relative retention period (RRT) of approximately 0.95 min. This 0.95 RRT impurity was recognized by LC-MS and then characterized by 1H NMR, 13C NMR, NMR HSQC, NMR HMBC and NMR D2O exchange analyses, and FT-IR techniques. Employed Zorbax XDB C18 eclipse as the main column and Ghost-Guard-LC, ANP00001 as the Ghostbuster column for 0.95 RRT molecule analysis. The mobile phase, phosphate buffer, and acetonitrile mixture, with a simple gradient, were provided to a column at a flow of 1.0 ml/min rate. Samples were evaluated employing a wavelength of 250 nm and injected sample at a volume of 3.0 µL. Good sensitivity was obtained (LOD –0.02% concentration and LOQ – 0.05% concentration) with levels extremely less than allowable limits (0.15%). In the concentration ranges of 0.045% (LOQ) – 0.225% (150% of permissible limits), the technique demonstrated the best linearity for 0.95 RRT molecule analysis, with coefficients of determination of 0.9958. The recovery rate ranged from 93.2% to 105.7%. This approach is shown to be capable of determining 0.95 RRT impurity levels in three rivaroxaban batch samples and one rivaroxaban commercial tablet.
OPTICAL AND ELECTRIC MODULUS STUDIES OF PMMA: CH3COOLi COMPLEXES WITH THE ADDITION OF EMIMTFSI
Authors: K. Sravanthi  , Sundari G. Sunita
Published: December 2022

Using solution casting technique PMMA with Lithium acetate of polymer electrolytes like PMMA (60 wt. %): CH3COOLi (40 wt. %): EMIMTFSI (0 wt. %, 0.5 wt. %, 1 wt. %) by incorporating ionic liquid are prepared. From UV-Visible studies maximum band gap (eV) is 2.8 eV for PMMA: CH3COOLi : EMIMTFSI (60:40:1 wt.%). Tangent dielectric loss revealed the behavior of the ion charge carrier’s polymer electrolyte system. Electric modulus studies revealed the information about charge carrier’s relaxation behavior. From the results, prepared polymer electrolyte films are the best candidates for energy storage devices
Logical-linguistic method for assessing the risk of specialized lending (on the example of project financing)
Authors: Krasavtseva Anna
Published: December 2022

Credit risk assessment is associated with uncertainty of many factors which are hard to describe mathematically. This reduces the probability of success of specialized lending as well. Among the various risk assessment methods suitable for specialized lending risk assessment, it’s possible to single out a scenario approach that uses the methods of fuzzy set theory to calculate the values of membership functions. However, the problem of ranking the set of project implementation scenarios for which a loan is requested is not studied enough. Despite the existing technical difficulties of risk factors management, the ranking of the risks of project implementation can be carried out by comparing with the ones from the database using the logical-linguistic classification method. The purpose of the study is to develop new methods of credit risk assessment based on the logical and linguistic classification of specialized lending projects as well as algorithms for assessing the credit risk of the project with determining its rating. The definition of a Project is used according to the concept of Project Finance as one of the classes of specialized lending. Methods: the assignment of weight factors for all subclasses of credit requirements, the assignment of risk levels for all values of the types of criteria, introduction of a table of the risk value assessment or the creditworthiness of the project, the formation of a database of reference attribute strings for all classes of projects, generating attribute strings for the analyzed project, assigning the analyzed project to the benchmark using the logical-linguistic classification method, assigning risk degree values for the analyzed project for all values of the criteria (attribute) types of the selected reference project, calculating the credit risk assessment of the analyzed project and determining the rating of the analyzed project for decision making. Results: based on the proposed risk assessment method, an algorithm for calculating the risk assessment of lending to the analyzed project with determining its rating was developed. Practical significance: the results of the research can be used in the development of computer program allowing to accelerate risk assessment of project financing.
Tendencies of labor content changes at different stages of historical development
Authors: Rudakov Igor
Published: December 2022

The article investigates how the main characteristics of labor activity are manifested during different stages of historical development. The authors propose to classify labor activity by four labor relations layering directions: free and bonded labor, prestigious and ordinary types of activity, skilled and unskilled labor, creative and routine labor. The main approaches to history periodization were analyzed and presented on a unified time scale. Based on the analysis of existing approaches, a generalized approach to the history periodization is proposed. For each historical period the manifestation of labor relations layering directions is shown: how they are manifested, how this manifestation changes from period to period, how labor activity is distributed within these characteristics. The visualization of how the labor relations layering directions manifest themselves at different historical stages of the proposed periodization is presented. The conclusion is made that the differentiation of labor has a wave-like character; the identified labor relations layering directions are manifested practically at all periods of history of economic activity, they change in different directions and interrelated with each other; creative and skilled labor relations layering types reflect the process of new technologies introduction; labor differentiation increases during the periods of technological revolutions.
The impact of foreign trade policy on food independence for separate commodity groups: Methodological aspects
Authors: Prokopyev Michail
Published: December 2022

The article considers the problem of the impact of foreign trade policy and external environment (world trade conditions) on the food independence of the country. The aim of the study is to develop a toolkit to quantify the impact of foreign trade policy on the indicator of food self-sufficiency in certain commodity groups of food and agricultural raw materials. The study is based on methodological approaches to assess the effect of import and export prices transfer in domestic prices under imperfect substitution and imperfect transformation. Imperfect substitution of the domestic and imported products on the domestic market and imperfect transformation of food flows between domestic and foreign markets are largely a consequence of the heterogeneity of commodity groups both on the import and export side, and domestic consumption. The reasons for heterogeneity of commodity groups are considered and their classification is given. In particular, the commodity groups of import substitution and export-oriented commodity groups are distinguished. For each of them the equilibrium conditions of supply and demand for domestic products on the domestic market, which have a significant impact on the formation of domestic prices, are considered. The effect of export and import prices transfer on aggregate demand (domestic and imported goods composite on the domestic market) and aggregate supply (domestic products composite for external and domestic markets) is shown. A toolkit is proposed to analyze the impact of "perturbations" — small deviations of exogenous parameters of foreign trade policy on food independence by separate commodity groups. A qualitative analysis of the impact of import tariffs, export subsidies and export duties, as well as world prices on the indicator of food self-sufficiency is given.
Statistical analysis and modeling of regional economy and science relationship
Authors: Gavrilets Yuriy
Published: December 2022

This paper proposes the analysis of regional economy dynamic model, reflecting the correlation between regional output, the number of employees and production funds. The attention is focused on the influence of different factors of science development on the economy. Those are: the number of PhD and researchers, the number of patents (of different kinds) and the new technologies. Besides, the sectoral orientation of the regional economy is taken into account, firstly, determined by the level of development of the mining and manufacturing. To build the models and make statistical calculations, the data of the official statistics is used. All the main parameters of the proposed model are estimated using modern computational optimization procedures given nonlinear dependencies. Statistical calculations showed that the obtained values of the main parameters of the models are significant, and the models themselves can be used for individual private estimations and forecasts. An important methodological feature of our approach: the necessary dependencies between model variables are identified with causal analysis methods and family hypothesis significance testing techniques. For this purpose, the general form of the production function is revealed by finding a graph of direct relationships of the entire system of the main variables. The resulting model is a methodological basis for constructing short-term forecasts of regional economic dynamics, which takes into account the contribution of science and the role of its individual components on economic growth. Besides, the dynamic model allows visualizing different variants of scenario analysis and gives an opportunity to optimize the trajectory. Selected computer calculations show how the qualitative nature of the trajectories of science and economy variables changes.
Effect of Trust on Responsibility for the Older and Future Generations: The Mediating Role of Perception of Age-Integration
Authors:   Korea Gerontological Society, Lee Ahyoung , Chung Soondool , Kim Juhyun , Song Boga
Published: December 2022

With the intergenerational solidarity as the theoretical background, this study attempted to investigate the effect of trust on responsibility for older and future generations and to confirm whether perception of age-integration plays a mediating role in these relationships. Data from an online survey of 1,000 adult men and women aged 20 to 79 nationwide were used, and the data were analyzed using structural equation modeling. As a result of the analyses, it was found that trust had a significant effect on both responsibility for the older generations and responsibility for future generations. In addition, perception of age-integration had a partial mediating role in these relationships. Practical and policy recommendations were proposed for the sustainable era of low fertility and population aging.
The conclusion sections in applied linguistics international journal articles written by Indonesian authors
Authors:   Universitas Bengkulu, Alkamillah Muhammad , Azwandi Azwandi ,   Universitas Bengkulu, Maisarah Ira ,   Universitas Bengkulu
Published: December 2022

This research attempts to describe the rhetorical structures of Indonesian author's in the conclusion section of applied linguistics international journals articles. The method employed in this study is descriptive quantitative. Thirty RA conclusion sections were extracted from two international journals; the Indonesian Journal of Applied Linguistics (IJAL) and TEFLIN journal, and examined based on the rhetorical move following Yang & Allison's proposed model of conclusion section (2003). The result revealed that, first, the majority of RA Conclusion sections (22 [73%] out of 30 conclusion sections) contain all elements of the Conclusion sections outlined by Yang and Allison (2003), namely: obligatory; move 1 (summarizing the study), the conventional moves; move 2 (Evaluating the study) and move 3 (deduction from the research); second, concerning steps features, most Indonesian authors tend to use step 1 in realizing move 2 (evaluating the study) This implies that those authors tend to justify their study by indicating the result of the research in evaluating the study in the conclusion section rather than stating the limitation of the research or evaluating the methodology in the conclusion section. In move 3, the Indonesian author tends to use step 1 (recommending future research) in realizing this move. This implies that the author prefers to state the possible areas for future study of study rather than drawing pedagogic implications. In conclusion, most Indonesian authors fulfilled the rhetorical structure of yang and Allison proposed model in their conclusion section.
Motivated Reasoning Leads Climate Change Deniers to Access Unreliable Online Sources of Information: Automated Text Analyses of Multiple Reddit Communities
Authors: Areni Charles
Published: December 2022

Motivated reasoning suggests that climate change deniers are more likely to access and comment on unreliable online sources of information that support their existing views and political ideologies, whereas climate change believers are more likely to access more objective sources of information not necessarily related to their political viewpoints. To test this hypothesis, an R program in RStudio scraped over 68,000 user-generated comments from multiple Reddit communities (i.e., subreddits) with opposing perspectives on climate change. Leximancer identified the internet domains associated with the URL links in user comments. Consistent with a motivated reasoning explanation, comments from climate change denial subreddits tended to include URL links to content from blogs and social media pages advocating similar ideological positions, whereas comments associated with subreddits based on belief in climate change tended to include URL links to content from news media and academic journals.
Updating of regulatory documentation regulating the organization and maintenance of the technological process at elevators and grain receiving enterprises
Authors:   FSBEI НЕ Krasnoyarsk State Agrarian University, Yanova M.A. , Oleynikova E.N. ,   FSBEI НЕ Krasnoyarsk State Agrarian University, Sharopatova А.V. ,   FSBEI НЕ Krasnoyarsk State Agrarian University, Nevzorov V.N. ,   FSBEI НЕ Krasnoyarsk State Agrarian University
Published: December 2022

The article provides an analysis of legislation and regulatory documents regulating the organization and maintenance of the technological process at grain elevators and grain receiving enterprises. In the course of research, the state of regulatory and legal regulation and mandatory requirements for the implementation of the activities of enterprises, compliance with which is subject to verification in the implementation of control and supervisory measures in the field of production organization and ensuring the quality and safety of grain and its processed products, has been determined. The substantiation of the improvement of technical regulation and the creation of a unified system of technical regulation at grain processing enterprises is given. The special significance for the elevator industry of changes in the Federal Law of the Russian Federation №4973-1 «On Grain», which contributed to the development of state regulation of the grain market, including the creation of the federal state information system «Grain» for the traceability of grain and its processed products, was noted.
Assessment of physico-chemical and technological parameters of grain of various varieties of spring and winter wheat and their suitability for baking purposes
Authors:   FGBOU VO Smolensk State Agricultural Academy, Terentiev S.E.
Published: December 2022

The article presents the results of many years of field experience in the Smolensk Agricultural Academy with spring and winter wheat varieties in order to assess the physicochemical and technological parameters of grain and flour and to select the most suitable varieties for baking purposes, zoned in the soil and climatic conditions of the Non-Chernozem zone of Russia. The study involved eight varieties of spring and winter wheat of Russian, Russian-Belarusian and German breeding. It is established that in production conditions, to increase the mass of 1000 grains, it is necessary to use biointensive and digital technologies for growing grain, which contributes to an increase in weight by more than 3–4 g. Winter wheat proved to be the most productive and valuable in terms of baking and technological qualities, surpassing spring wheat in gluten content, which makes it possible to use flour from its grain for the production of cereals, confectionery and pasta. Laboratory studies have shown that the level of vitreousness depends on the weight of the grain. Thus, in the smaller grain varieties of spring wheat Trizo and Agate, the vitreousness was 65–67%. In addition, the vitreousness is influenced by the humidity level: in wet years, the vitreousness of grains of all varieties of spring and winter wheat decreased by 8–12% relative to the hydrothermal coefficient of growing conditions. All varieties of winter and spring wheat in the conditions of field experience showed plasticity in various climatic conditions and the ability to form a full-scale weight from 736 to 809 g/l corresponding to the genotype of the studied variety. There were no fundamental differences in nature between the varieties. The least variability of nature depending on the soil and climatic conditions of the growing years was observed in intensive varieties of spring wheat, Madam, Agate, Zlata and Radmir, and in winter wheat varieties Volzhskaya 22, Lgovskaya 8, Nemchinovskaya 85. According to the results of the study, the varieties of spring wheat Radmir and Madam, winter wheat – Volzhskaya 22, Measure, Nemchinovskaya 85 have the highest baking properties.
Analisa Kerapatan dan Kadar Abu pada Kayu Kapur (Drobalanops sp.) yang Terinfeksi Jamur Pelapuk Putih (Schizophyllum commune)
Authors: Yustika Erlina , Erwin Erwin , Husien Nani , Budi Agus Sulistyo , Wahyuni Sri
Published: December 2022

Penelitan ini merupakan lanjutan dari penelitian sebelumnya mengenai kehilangan berat kayu kapur (Dryobalanops sp) yang diinokulasi menggunakan jamur pelapuk putih (Schizophyllum commune) dengan nilai kehilangan berat kayu sebesar 0,12%. Inokulasi jamur S.commune dilakukan terhadap sampel Kayu Kapur pada media PDA (Potato Dextrose Agar) dengan masa inkubasi selama 4 minggu, Pengujian nilai kerapatan kayu dan nilai kadar abu dilakukan sebelum dan sesudah inokulasi dengan masing-masing menggunakan standar DIN 32182 dan TAPPI T211 om-93. Hasil penelitian menunjukkan terjadinya perbedaan yang tidak signifikan pada penurunan nilai kerapatan kayu dan peningkatan nilai kadar abu dari kayu kapur yang diinfeksi oleh jamur S.commune pada masa inkubasi selama 4 minggu
A Review on Techniques and Applications of Gastroretentive Drug Delivery System
Authors: Sharma Hrishabh , Sharma Ashutosh , Bansal Dr. Mayank , Kumar Gupta Dr. Rakesh
Published: December 2022

A Controlled release dose forms have been widely utilized to enhance treatment with a number of significant medications. However, a number of physiological challenges, including the inability to control and localize the system within the target region of the gastrointestinal tract and the extremely changeable nature of the gastric emptying process, pose challenges to the development processes. The bioavailability and periods needed to reach peak plasma levels may be unpredictable as a result of this diversity. The goal of this review on gastro retentive drug delivery systems was to gather the most recent research with a special emphasis on the numerous gastro retentive technologies that have lately emerged as leading approaches in the area of site-specific oral controlled release drug delivery. We have included crucial elements in order to comprehend numerous physiological challenges to achieve stomach retention.
A szabálysértési törvény első tíz éve konferencia tudományos előadásai dióhéjban
Authors: Skorka Tamás , Buzás Gábor
Published: December 2022

A konferencia szervezőinek – az Országos Rendőr-főkapitányság Rendészeti Szervek (ORFK RSZ) Igazgatásrendészeti Főosztálya és a Nemzeti Közszolgálati Egyetem Rendészettudományi Kar (NKE RTK) Igazgatásrendészeti és Nemzetközi Rendészeti Tanszéke – célja volt, hogy az évforduló kapcsán a jogalkalmazóknak – a rendőrség és a bíróság szakemberei –, az oktatóknak és a tudományos kutatóknak lehetőséget biztosítson az együtt gondolkodásra, a tapasztalatok bemutatására. A szervezők leszögezték, hogy egy ilyen szakmai konferencia amellett, hogy a szakterület végrehajtó szervei és a szaktanszék együttműködésének egyik meghatározó eleme, kiváló forrása az oktatásban hasznosítható ismereteknek is. A beszámoló az elhangzott előadásokat ismerteti – röviden.
РЕЗУЛЬТАТИ ЛІКУВАННЯ ДІТЕЙ, ХВОРИХ НА ЗЛОЯКІСНІ ПУХЛИНИ ЦЕНТРАЛЬНОЇ НЕРВОВОЇ СИСТЕМИ, В ХАРКІВСЬКОМУ РЕГІОНІ
Authors: БІЛЕЦЬКИЙ Володимир
Published: December 2022

Анотація. Пухлини центральної нервової системи (ЦНС) у дітей серед інших новоутворень посідають друге місце після лейкозів 17,6%. Згідно зі статистичними даними, щорічно у світі реєструється близько 10000 захворювань. Спектр гістологічних форм пухлин ЦНС надзвичайно широкий і різноманітний. Нині відомо більш ніж 120 форм і різновидів таких новоутворень. Однак приблизно 80% випадків у педіатричній практиці представлено такими гістологічними формами: медулобластомою, ювенільною пілоцитарною астроцитомою, дифузно-інфільтративними астроцитомами, епендімомою і краніофарингеомою. Інші пухлини центральної нервової системи у дітей трапляються рідше [2; 3; 5]. Між гістологічними ознаками й біологічною поведінкою пухлин ЦНС можуть виникати певні невідповідності. Найбільш яскраво це проявляється в низці випадків добре диференційованих менінгеом, які можуть рости інвазивно в навколишні тканини (у кістки черепа й у мозок) і навіть метастазувати у внутрішні органі. При цьому в первинному вогнищі не визначається судинна інвазія. Таким чином, у разі постановки діагнозу й визначення ступеня злоякісності необхідно враховувати індивідуальні особливості кожної конкретної пухлини ЦНС, що не завжди вдається повною мірою за використання наявних методів дослідження. Різноманітність гістологічних форм пухлин, відмінність їх молекулярно-біологічних маркерів потребують виваженого та диференційованого підходу до вибору методу лікування. А прогноз захворювання напряму залежить від правильності вибору тактики. Лікування злоякісних пухлин ЦНС – складний мультидисциплінарний процес, який включає у себе імуногенетичні дослідження, етапи нейрохірургічного лікування, проведення хіміо- та променевої терапії. Причому стратегія лікування залежить не тільки від гістологічної структури пухлини, але й від віку дитини, наявності локальної чи розповсюдженої пухлини, а також від локалізації пухлинних вогнищ у структурах головного та спинного мозку. У статті наведені результати лікування пухлин ЦНС у дітей за даними комунального некомерційного підприємства Харківської обласної ради «Обласна дитяча клінічна лікарня № 1» за 5 років. Проведений аналіз різних сучасних варіантів лікування та ефективності терапії.
Nonelementary irreducible representations of Spin(n, 1)
Authors: Kovačević Domagoj , Kraljević Hrvoje
Published: December 2022

We study corners and fundamental corners of the irreducible subquotients of reducible elementary representations of the groups G = Spin(n, 1). For even n we obtain results in a way analogous to the results in [8] for the groups SU(n, 1). Especially, we again get a bijection between the nonelementary part Gˆ0 of the unitary dual Gˆ and the unitary dual K. ˆ In the case of odd n we get a bijection between Gˆ0 and a true subset of K.
Exploring the Intersection Between Academic and Professional Practice During the COVID-19 Pandemic: Undergraduate and Graduate Nursing Students’ Experiences
Authors: Espin Sherry , LeGrow Karen , Bookey-Bassett Sue , Rose Donald , Santa Mina Elaine , Indar Alyssa
Published: December 2022

Background: The coronavirus disease-2019 (COVID-19) pandemic has implications for students who are also nurses. Purpose and Methods: This qualitative descriptive study used a practice development approach to explore the intersection between academic and professional work experiences for undergraduate Post-Diploma Registered Practical Nurses bridging to Registered Nurse Bachelor of Science in Nursing students and Master of Nursing graduate nursing students during the ﬁrst wave of the COVID-19 pandemic. The study incorporated critical aesthetic reﬂections that focused on the personal and aesthetic ways of knowing, as a data collection approach and knowledge dissemination strategy. Results: Analysis of the narrative component of participants’ reﬂections revealed the following themes: sensing a “call to duty,” experiencing a myriad of emotions, shifting societal and individual perceptions of nursing, and learning in an uncertain environment. Conclusions: The results of the study can inform educational strategies and academic policies to support this unique nursing population, who are frontline practitioners as well as student learners.
Elucidating the information exchange during interfacility care transitions: Insights from a Qualitative Study
Authors: Jeffs Lianne , Saragosa Marianne , Law Madelyn P. , Kuluski Kerry , Espin Sherry , Merkley Jane , Bell Chaim M.
Published: December 2022

Objective To explore the perceptions of patients, their caregivers and healthcare professionals associated with the exchange of information during transitioning from two acute care hospitals to one rehabilitation hospital.

Design An exploratory qualitative study using semistructured interviews and observation.

Participants and setting Patients over the age of 65 years admitted to an orthopaedic unit for a non-elective admission, their caregivers and healthcare professionals involved in their care. Participating sites included orthopaedic inpatient units from two acute care teaching hospitals and one orthopaedic unit at a rehabilitation hospital in an urban setting.

Findings Three distinct themes emerged from participants' narrative of their transitional care experience: (1) having no clue what the care plan is, (2) being told and notified about the plan and (3) experiencing challenges absorbing information. Participating patients and their caregivers reported not being engaged in an active discussion with healthcare professionals about their care transition plan. Several healthcare professionals described withholding information within the plan until they themselves were clear about the transition outcomes.

Conclusion This study highlights the need to increase efforts to ensure that effective information exchanges occur during transition from acute care hospital to rehabilitation settings.
A study of apparel consumer behaviour in China and Taiwan
Authors: Rahman Osmud , Fung Benjamin C.M. , Chen Zhimin , Chang Wei-Lun , Gao Xiang
Published: December 2022

To better understand consumer behaviour and preferences for apparel shopping in Asia, we collected data through questionnaire surveys in China and Taiwan on three topics: online and offline shopping behaviours; product evaluative criteria; and fashion information sources. The study showed that women in both China and Taiwan shopped more frequently than men. Chinese consumers shopped more frequently online than did their Taiwanese counterparts. Both Chinese and Taiwanese consumers cited ‘fit’ and ‘comfort’ as the two most important evaluative criteria for clothing, while ‘brand name’ and ‘country of origin’ were the least important cues. Both Chinese and Taiwanese participants cited ‘friends’ as their most important fashion information source, with ‘siblings’ and ‘parents’ being the two least important sources.
Quantifying between-individual variation using high-throughput phenotyping of behavioural traits in the fruit fly (Drosophila melanogaster)
Authors: Macartney Erin , Pottier Patrice , Burke Samantha , Drobniak Szymon , Nakagawa Shinichi
Published: December 2022

Behavioural phenotyping is often time and labour-intensive, which can come at a cost to sample size and statistical precision. This is particularly a concern given that behaviours are often highly variable within and between individuals, so naturally requires a larger sample size. Drosophila melanogaster is a common model system in many research fields, and behavioural observations are frequently required. While D. melanogaster has a rapid lifecycle that enables large numbers of flies to be reared for experiments, they are still subject to methodological bottlenecks for behavioural observations. Additionally, their small and delicate bodies make it difficult to observe certain behaviours in real-time, for example, in movement tracking or when performing repeated assays on the same individuals. Here, we present a method, pilot data, custom data processing and analysis scripts for high-throughput behavioural phenotyping in D. melanogaster, as well as general remarks for future studies. We used automatic tracking units to measure three behaviours in the same individuals: locomotor activity, exploratory behaviour in a Y-maze, and habituation to a startle response stimulus. We then examined between-individual variation and trait correlations using our pilot data. Through this, we show that these behaviours are amenable to high-throughput automated tracking, with locomotor activity generating the most straightforward and high-quality data. These methods can be used to free up time and labour to allocate to increasing sample sizes and can be used to address a range of biological questions in ecology, evolution, and beyond.
Design of High-Speed Dual Port 8T SRAM Cell with Simultaneous and Parallel READ-WRITE Feature
Authors: Rahman Aura Shourin , M. Ishraqul Huq S. , N. Biswas Satyendra
Published: December 2022

An innovative 8 transistor (8T) static random access memory (SRAM) architecture with a simple and reliable read operation is presented in this study. LTspice software is used to implement the suggested topology in the 16nm predictive technology model (PTM). Investigations into and comparisons with conventional 6T, 8T, 9T, and 10T SRAM cells have been made regarding read and write operations' delay and power consumption as well as power delay product (PDP). The simulation outcomes show that the suggested design offers the fastest read operation and PDP optimization overall. Compared to the current 6T and 9T topologies, the noise margin is also enhanced. Finally, the comparison of the figure of merit (FoM) indicates the best efficiency of the proposed design.
A comparative study of hash algorithms with the prospect of developing a CAN bus authentication technique
Authors: Zniti Asmae , El Ouazzani Nabih
Published: December 2022

In this paper, the performances of SHA-3 final round candidates along with new versions of other hash algorithms are analyzed and compared. An ARM-Cortex A9 microcontroller and a Spartan -3 FPGA circuit are involved in the study, with emphasis placed on the number of cycles and the authentication speed. These hash functions are implemented and tested resulting in a set of ranked algorithms in terms of the specified metrics. Taking into account the performances of the most efficient algorithms and the proposed hardware platform components, an authentication technique can be developed as a possible solution to the limitations and weaknesses of automotive CAN (Controlled Area Network) bus – based embedded systems in terms of security, privacy and integrity. From there, the main elements of such a potential structure are set forth.
An empirical study on English-Mizo Statistical Machine Translation with Bible Corpus
Authors: Sveta Devi Chanambam , Sanayai Meetei Loitongbam , Syam Purkayastha Bipul
Published: December 2022

Machine Translation (MT) is the process of automatically converting the text or speech in one natural language to another language with the help of a machine. This work presents a Bidirectional Statistical Machine Translation (SMT) system of an extremely low resource language pair Mizo-English, built in a low resource setting. A total of 30800 sentences are collected from the English Bible dataset and manually translated to Mizo by a native linguistic expert to generate the English-Mizo parallel dataset. After subjecting to various pre-processing steps, the parallel dataset is used to build our MT system using MOSES tools. Our framework uses different tools, such as GIZA++ for creating the Translation Model (TM) and IRSTLM to determine the probability of the target model. The quality of our MT system is evaluated using two automatic evaluation metrics: BLEU and METEOR. Our MT systems are also manually evaluated using two parameters: adequacy and fluency.
Decision Support Machine- A Hybrid Model for Sentiment Analysis of News Headlines of Stock Market
Authors: Sharma Kirti , Bhalla Rajni
Published: December 2022

Forecasting and making speculations about the financial market is intriguing and enticing for many of us. Predicting sentiments in the field of finance is a difficult thing as there is a special language that is used in financial markets and the data is unlabeled. Generalized models are not sufficient because the words that are used in financial markets have a completely different meaning when compared to their regular use. This paper represents the study of the stock price fluctuations and forecasting of the future stock prices using financial news about the big IT giants. NLP techniques should be applied to extract the correct sentiments out of the statements. This paper proposes a hybrid Machine Learning model DSM i.e. Decision Support Machine based on Support Vector Machine and Decision Tree. In this study news headlines dataset is preprocessed and then used for making predictions. The results show that the proposed model DSM got an accuracy of 79.75%. Results are then compared with the real-time stock market data for the same time duration, thus giving us a better picture of the actual changes. DSM is also compared with BERT, TextBlob, Decision Tree, Naïve Bayes, NLTK-Vader, SVM and KNN. The proposed model can further be extended if more datasets associated with investors’ sentiments can be used for training.
Identifying and Classifying an Ovarian Cyst using SCBOD (Size and Count-Based Ovarian Detection) Algorithm in Ultrasound Image
Authors: Jeevitha S. , Priya N.
Published: December 2022

Polycystic ovaries are a sign of increasing infertility in the female population worldwide. An excessive number of follicle formations leads to polycystic ovarian syndromes. It affects the female reproductive cycle and leads to disorders such as cardiovascular issues, diabetes mellitus, and cancer. Calculating the number of follicles and detecting the follicle size is still challenging due to time complexity. Since the size of follicles and the greater number mislead the detection of the ovarian type in the ultrasound image. The ultrasound images contain more speckle noise, making the ovarian follicles difficult to see manually. A new convenient method is proposed for the detection of follicles and ovary classification is based on the measurement of size and the count of each follicle. In this paper, the work is divided into four steps, the first step preprocessing the ultrasound image. In the second step, the segmentation process is applied for object selection and separation process using an improved watershed algorithm. In the third step, based on the geometrical and statistical features the object is recognized by SCBOD accurately using various parameters such as size, count, mean, standard deviation, etc., Finally, an SVM classifier is used for classification to conclude the Polycystic ovary syndrome(PCOS) and Non- PCOS. This algorithm is proposed to the physician to find the ovarian follicles rapidly, which will offer accurate performance and is more effective in execution by adopting the SCBOD (Size and Count-based Object Detection) method.
ResViT
Authors: Ahmad Wasim , Ali Imad , Adil Shahzad Sahibzada , Hashmi Ammarah , Ghaffar Faisal
Published: December 2022

Deepfake makes it quite easy to synthesize videos or images using deep learning techniques, which leads to substantial danger and worry for most of the world's renowned people. Spreading false news or synthesizing one's video or image can harm people and their lack of trust on social and electronic media. To efficiently identify deepfake images, we propose ResViT, which uses the ResNet model for feature extraction, while the vision transformer is used for classification. The ResViT architecture uses the feature extractor to extract features from the images of the videos, which are used to classify the input as fake or real. Moreover, the ResViT architectures focus equally on data pre-processing, as it improves performance. We conducted extensive experiments on the five mostly used datasets our results with the baseline model on the following datasets of Celeb-DF, Celeb-DFv2, FaceForensics++, FF-Deepfake Detection, and DFDC2. Our analysis revealed that ResViT performed better than the baseline and achieved the prediction accuracy of 80.48%, 87.23%, 75.62%, 78.45%, and 84.55% on Celeb-DF, Celeb-DFv2, FaceForensics++, FF-Deepfake Detection, and DFDC2 datasets, respectively.
Pengolahan Air Gambut Menjadi Air Bersih dengan Teknologi Sederhana di Kecamatan Sabangau Kelurahan Bangkirai Kota Palangka Raya
Authors: Bella Ayuni sinam , Marlina Sari , Santoso Achmad Imam
Published: December 2022

Air adalah senyawa yang penting bagi semua makhluk yang ada di bumi, air memiliki fungsi sebagai penyembuh penyakit bisa dikatakan air merupakan senyawa netral yang keberadaannya sangat diperhatikan oleh semua jenis makhluk hidup dimuka bumi ini. air beserta sumber-sumbernya merupakan salah satu kekayaan alam yang mutlak dibutuhkan oleh makhluk hidup guna menopang kelangsungan hidup dan memelihara kesehatannya. berbeda halnya dengan air gambut adalah air permukaan yang banyak dujympai di daerah lahan gambut atau dataran rendah terutama dipulau kalimantan khususnya palangka raya, air gambut mengandung senyawa zat organik ter;larut yang menyebabkan air menjadi berwarna coklat dan bersifat asam dengan Ph 3-5, sehingga perlu pengolahan khusus sebelum digunakan dan dikonsumsi. proses pembentukan gambut dimulai dari adanya danau dangkal yang secara perlahan ditumbuhi oleh tanaman air dan vegetasi lahan basah. air gambut di kelurahan bangkirai, kecamatan sabangau yang sudah diuji kualitas air nya berdasarkan parameter baku mutu air tidak memenuhi persyaratan kualitas air bersih.
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency
Authors: Rein Avigail , Geron Ifat , Kugler Eitan , Fishman Hila , Gottlieb Eyal , Abramovich Ifat , Giladi Amir , Amit Ido , Mulet-Lazaro Roger , Delwel Ruud , Gröschel Stefan , Levin-Zaidman Smadar , Dezorella Nili , Holdengreber Vered , Rao Tata Nageswara , Yacobovich Joanne , Steinberg-Shemer Orna , Huang Qiu-Hua , Tan Yun , Chen Sai-Juan , Izraeli Shai , Birger Yehudit
Published: December 2022

Mono-Allelic germline disruptions of the transcription factor GATA2 result in a propensity for developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) affecting more than 85% of carriers. How a partial loss of GATA2 functionality enables leukemic transformation occurring years later in life, is unclear. This question is unsolved mainly due to lack of informative models, as Gata2 heterozygote mice do not develop hematologic malignancies. Here we show that two different germline Gata2 mutations (tgERG/GATA2het and tgERG/Gata2L359V) accelerate AML in mice expressing the human hematopoietic stem cell regulator ERG. Analysis of ERG/Gata2het fetal liver and bone marrow derived hematopoietic cells revealed a distinct pre-leukemic phenotype. This was characterized by enhanced transition from stem to progenitor state, increased proliferation, and a striking mitochondrial phenotype, consisting of highly expressed Oxidative- Phosphorylation related gene-sets, elevated oxygen consumption rates, and notably, markedly distorted mitochondrial morphology. Importantly, the same mitochondrial gene-expression signature was observed in human AMLs harboring GATA2 aberrations. Similar to the observations in mice, non-leukemic bone marrows from children with germline GATA2 mutation demonstrated marked mitochondrial abnormalities. Thus, we observed the tumor suppressive effects of GATA2 in two germline Gata2 genetic mouse models. As oncogenic mutations often accumulate with age, Gata2 deficiency mediated priming of hematopoietic cells for oncogenic transformation may explain the earlier occurrence of MDS/AML in patients with GATA2 germline mutation. The mitochondrial phenotype is a potential therapeutic opportunity for prevention of leukemic transformation in these patients.