bluuebunny/crossref_metadata_2025 huggingface dataset:
Żresz jak świnia! Jedz jak człowiek! – czyli o niektórych stereotypach językowych dotyczących jedzenia
Authors: Gasz Agnieszka
Published: December 2021

Jedzenie (odżywianie się) to czynność (życiowa) właściwa zarówno ludziom, jak i zwierzętom. Wyznacza więc ono pewien wspólny obszar łączący dwie różne perspektywy interdyscyplinarnych badań, określanych odpowiednio jako: food studies i animal studies.  Celem niniejszego artykułu jest omówienie ważniejszych stereotypów językowych dotyczących jedzenia. Na podstawie analizy najczęściej używanych w polszczyźnie frazeologizmów zawierających komponenty jeść i żreć zostanie podjęta próba wykrycia podstawowych składników konotacyjnych ich znaczenia, a zarazem rekonstrukcji wyłaniającego się z nich obrazu jedzenia. W trakcie analizy zgromadzonego materiału językowego zostaną wykorzystane wybrane procedury badawcze wypracowane w obrębie semantyki kulturowej (elementy definicji kognitywnej, metafora pojęciowa, animalizacja).
Ptasi świat utrwalony w fitonimach
Authors: Wierzbicka Agnieszka
Published: December 2021

Fitonimy są niezwykle interesującą kategorią leksykalną i zawierają w sobie istotne właściwości semantyczne języka polskiego. Próbując odtworzyć proces nominacji poszczególnych gatunków widzimy, jak wiele zależy tu od percepcji człowieka i obserwacji otaczającej go rzeczywistości. Znaczenia zawarte w potocznych, gwarowych i botanicznych nazwach roślin ujawniają nam niezwykle bogaty i barwny świat widziany z perspektywy antropocentrycznej. Szczegółowa analiza semantyczna nazw takich jak jaskółcze ziele, kaczeniec, kurzyślad, kacze pyski, rdest ptasi, ptasie oczko i inne, prowadzi do ciekawych wniosków – nazwy roślin często niosą ze sobą treści metaforyczne, oparte na percepcji zmysłowej i doświadczeniu, a także niejednokrotnie na skojarzeniach z bliskim światowi fauny światem ptaków. W swoim artykule autorka pokaże, że system nominowania roślin w dużej mierze opiera się na konceptualizacji świata i kategoryzacji rzeczywistości.
Katja M. Guenther: The Lives and Deaths of Shelter Animals. Stanford, CA: Stanford University Press, 2020. 295 pp.
Authors: Nikitina Ekaterina
Published: December 2021

Nota o książce: Katja M. Guenther: The Lives and Deaths of Shelter Animals. Stanford, California: Stanford University Press, 2020. 295 pp.
You Just Need More Resilience: Racial Gaslighting as “Othering”
Authors: Vasquez Ramon
Published: December 2021

This work de-familiarizes notions of resilience by theorizing the way racial gaslighting operates in teacher education. By focusing on the racial gaslighting of  BIPOC faculty, this paper shows how whiteness functions as a dominant process in anti-racist teacher education programs through the recentering of White feelings and interests. Ultimately this work calls for a  new approach, one that situates resilience within a non-Euro-centered context of resistance to oppression. This could provide a catalyst for a more humane resilience.@font-face{font-family:"Cambria Math";panose-1:2 4 5 3 5 4 6 3 2 4;mso-font-charset:0;mso-generic-font-family:roman;mso-font-pitch:variable;mso-font-signature:-536870145 1107305727 0 0 415 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:"";margin:0in;mso-pagination:widow-orphan;font-size:12.0pt;font-family:"Times New Roman",serif;mso-fareast-font-family:"Times New Roman";}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-family:"Calibri",sans-serif;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:minor-bidi;}div.WordSection1{page:WordSection1;}
Letter from the Editor
Authors: Gratteau-Zinnel Travis
Published: December 2021

Letter from the Editor 
Poduzetnički inkubatori kao oblik poduzetničke potporne institucije u Hrvatskoj
Authors: Morić Milovanović Bojan , Tutić Željka
Published: December 2021

Poduzetnički inkubatori jedan su od oblika potpornih institucija razvoja poduzetništva, pri čemu je njihova osnovna svrha poticanje poduzetničkoga okružja i osiguravanje preduvjeta razvoja poduzetnika na određenome području pružanjem raznih usluga. Poduzetnički inkubatori osnivaju se radi dinamiziranja lokalnog i regionalnog ekonomskog razvoja jer su im ciljna skupina poduzeća iz područja njihove županije ili grada. Svrha je ovog rada istražiti ulogu poduzetničkih inkubatora u pružanju potpore malim i srednjim poduzećima u Hrvatskoj. U radu se žele prikazati neke od osnovnih karakteristika poduzetničkih inkubatora, njihove odrednice i prakse poslovanja te istražiti i analizira ti ponuda usluga koje inkubatori pružaju svojim stanarima. Također, u radu se nastoje ustanoviti osnovni ciljevi poslovanja, izvori financiranja te analizirati uspješnost inkubatora. Empirijski podaci prikupljeni su anketnim upitnikom na uzorku od 34 poduzetnička inkubatora, pri čemu je metoda deskriptivne statističke analize korištena radi pružanja potanka opisa trenutačnog stanja, karakteristika te poslovanja poduzetničkih inkubatora u Hrvatskoj.
Implementation and Application of Artificial Intelligence in Selected Public Services
Authors: Štefanišinová Nikola , Jakuš Muthová Nikoleta , Štrangfeldová Jana , Šulajová Katarína
Published: December 2021

Data-intensive technologies, such as artificial intelligence, imply huge opportunities for transforming the delivery of healthcare and social services, improving people’s quality of life and working in the health and welfare system. The aim of this paper is to present examples of the implementation of artificial intelligence techniques in healthcare and social services and to sketch the trends and challenges in the adoption of artificial intelligence techniques, with an emphasis on the public sector and selected public services. Analysis is based on a realistic assessment of current artificial intelligence technologies and their anticipated development. Besides the benefits and potential opportunities for healthcare and social services, there are also challenges for governments. Understanding the huge potential of artificial intelligence as well as its limitations will be a key step forward, but it is essential to avoid the trap of an overestimation of artificial intelligence potential.
The Role of Agencies in Creating Network Approach in Higher Education
Authors: Dujmović Bocka Jelena , Bakota Boris
Published: December 2021

An analysis of different aspects regarding the creation of networks within the Croatian higher education system is presented in the paper. The larger part of the paper refers to the analysis of public services in general and the network approach in public administration in particular. The state of the higher education system is presented through the inclusion of market and network principles and the establishment of numerous actors in this field by which effectiveness of this field of public administration is trying to be improved. The aim of the detailed examinations is to pro-vide an overview of all relevant actors whose interactions and roles resemble network-like relationships. To examine the starting hypothesis that neo-managerial approach leads to networking within the higher education system, an empirical study was conducted at the Josip Juraj Strossmayer University in Osijek, Croatia among the teaching staff and students. The final chapters of the paper present and discuss research results which principally support the initial assumptions.
Evaluation of the Relationship of Democracy and Governance
Authors: Karatas Adnan
Published: December 2021

Economic, social, political and technological developments have greatly influenced the field of public administration, and new paradigms have been introduced accordingly. Governance, one of these approaches, deals with controversial issues such as changing the state-citizen relationship, strengthening democracy, improving the service provision capacity of the government, and the rule of law, and are discussed at global, national and local levels. Within the scope of this study, the effect of governance on democracy is investigated. Accordingly, the theoretical claim that governance has an impact on democracy is tested with an empirical analysis using quantitative data. In order to test this claim, democracy and governance indices are analysed statistically. Based on these data, various correlation and regression analyses can be made. As a result, it has been determined that governance has a very high effect on democracy. Moreover, there is a high level of correlation and effect between the sub-dimensions of both indices.
Assessment of Knowledge and Healthcare Related Practices of Caregivers Regarding Home Management of Children with Nephrotic Syndrome
Authors: Madhushani J.S.S.  , Bandara W.V.R.T.D.G.
Published: December 2021

Introduction: Nephrotic Syndrome (NS) is the commonest chronic glomerular disorder characterized by heavy proteinuria, hypoproteinaemia, oedema and hyperlipidaemia. Parental motivation and involvement are essential for home management of a child with NS. This study was conducted to assess caregivers' knowledge and healthcare related practices regarding home management of children with NS. Methods: A descriptive cross-sectional study was conducted among caregivers (n=94) attending the Paediatric Nephrology Clinic (PNC) at the Teaching Hospital Karapitiya, Sri Lanka. Data were collected through an interviewer-administered questionnaire. Data were analyzed using SPSS version 20. Results: The majority of the respondents (71.3%) were mothers. The majority of children with NS in the study sample were boys (70.2%), and their mean age was 7.6±3 years. About 40.4% of children had onset of disease at the age of 2-3 years. The majority of participants (53.2%) had scored more than 75 marks for knowledge. The practice score of the majority (66.0%) was between 50-100. The mean knowledge score was significantly higher in the participants who have managed their child with NS for 6-8 years (p=0.006) and for 9-11 years (p=0.019), compared to the participants who have managed their child with NS for 3-5 years. The mean knowledge score was significantly higher in the participants with the family history with NS in compared to the participants without family history of NS (p=0.001). A statistically significant association was found between mean practice score and the number of living children in the family (p=0.009). Mean practice score of the participants who had more than four living children was significantly higher than the participants who had two living children in their family (p=0.002). However, a significant negative correlation was observed between knowledge on NS and healthcare related practices of the participants (r= -0.240, n=94, p=0.020, 2-tailed). Conclusions: The overall knowledge and practices of parents/caregivers regarding home management of children with NS attending to the PNC, Teaching Hospital Karapitiya, Sri Lanka, was adequate and satisfactory.

Keywords: Home management, Paediatric, Nephrotic Syndrome, Knowledge, Practice
The Impact of Future Economic Stability and Family Influence on Students’ Motivation for Higher Education: A Study on IIUM Students
Authors: Abdulhameed Kamoludeen Olasunkanmi , Khalid Madihah
Published: December 2021

This study was conducted to investigate the relationship between future economic stability (FES), family influence (FI) and students’ motivation for higher education (MFHE) based on the perceptions of undergraduate students in IIUM. The questionnaire used was self-developed and piloted with 263 undergraduate students, who were sampled purposely. Content validity, construct validity and – the Cronbach’s alpha for reliability were conducted to validate the instrument. SPSS V25 was used to analyze the data by manipulating the descriptive and inferential statistics. The findings from data analysis indicated that IIUM students held positive perception towards FES, FI and MFHE. The results also revealed a positive and significant relationship between FES, FI and MFHE, and that FES and FI were found to be significant predictors of MFHE. As an implication, higher education institutions as well as parents are urged to support their wards in terms of employment opportunities and continuous parental support, as the impact of future economic stability and family influence have been confirmed in this study as part of the reasons behind students’ motivation for higher education learning.
The effects of two loading patterns of resistance training (skewed pyramid & reverse step) on some physical and physiological capabilities of non-athlete men
Authors: SAYYAH Ali , ASGHARİ Ehsan , ARAZİ Hamid
Published: December 2021

The present study aims to investigate the effects of two different loading patterns of resistance training (skewed pyramid & reverse step) on some physical and physiological capabilities of non-athlete men. For this purpose, 30 non-athlete men with a resistance training experience of less than six months are selected among volunteers and randomly assigned to control (n=10), reverse step loading (n=10), and skewed pyramid loading (n=10) groups. Their strength, speed, agility, explosive power, muscle volume, and body composition were measured before and after 10 weeks of training. Two-way ANOVA and Tukey post-hoc tests were used for statistical analysis. Results show that in both groups of skewed pyramid and reverse step, the variables of strength, speed, agility, explosive power, and muscle volume have had a significant increase compared to the control group. Also, the body composition of the training groups significantly improved and fat percentage decreased (p˂0.05). However, there were more positive changes in thigh volume, lower body strength and body fat percentage in skewed pyramid compared to reverse step (p˂0.05). Generally, it seems that the skewed pyramid pattern has a higher importance and priority than the reverse step pattern in improving both physical and physiological factors, especially muscle strength and muscle volume development of non-athlete men.
The Effectiveness of Organic Fertilizers as a Means of Adapting to Climate Change
Authors:   South-Ukrainian branch of L. Pogorilyy UkrNDIPVT, Maliarchuk V. , Fedorchuk E.
Published: December 2021

Abstract. The article presents the results of research on the use of liquid organic fertilizer in the cultivation of winter wheat in compliance with the requirements of organic farming in the grain-steam crop rotation of the experimental field of the South-Ukrainian branch of L. Pogorilyy UkrNDIPVT in 2020-2021. The purpose of research is to analyze the effectiveness of organic fertilizers as a strategic priority for the development of low-carbon agricultural land use (agrochemical direction of adaptation to climate change). Determining the impact of liquid organic fertilizer "Riverm" on the quality of the soil and its ability to retain moisture, as well as to increase the productivity of winter wheat in crop rotations on non-irrigated lands of southern Ukraine. Research methods: field quantitative-weight, visual and laboratory methods. Mathematical and statistical methods used to systematize and generalize the obtained results. Research results. It has been experimentally established that the use of new generation organic fertilizers suspends the reduction of humus content and contributes to the achievement of its deficit-free balance. In particular, during the study period there was a significant increase in the content of organic matter (labile humus) in the soil by 6.01 %, which in two years rose to the level of average values (2.10 %), against a low level of security (1.98 %) to use of “Riverm” fertilizer. Conclusions. The effectiveness of liquid organic fertilizer "Riverm" in the cultivation of winter wheat Khersonskaya-99 in the southern steppe of Ukraine, which improves nutrition and significantly increases the content of mineral nutrients (NPK), and as a result helps to increase the yield of winter wheat on average at 14 %.
Technologies and Equipment for Applying Fertilizers with Water by Sprinkling Machines
Authors:   South-Ukrainian branch of UKRNIPVT them. L. Pogorylogo, Sidorenko V.
Published: December 2021

Summary. The article presents the results of research on the technology of compatible introduction of mineral fertilizers with irrigation water of sprinkling machines and testing equipment for fertigation. The purpose of research - technological analysis of various types of equipment for combining fertilizer, which is used in the production practice of S.-G. Manufacturers, definition of their basic operational and technological indicators and efficiency of using fertigation technology. Research methods: theoretical, empirical - analysis of information resources, analysis of the practice of using fertigation; laboratory-field tests for information data. using measurements and experiments. Research results. The traditional methods of fertilizing - superficial and local, in particular, the disadvantages of their use are analyzed. It was noted that one of the ways of intensifying irrigated agriculture, in which the requirements for the effective use of fertilizers and reducing resource costs are multipurpose use of irrigation equipment, namely combining irrigation with fertilizers along with irrigation water. The high efficacy of fertigation is established, which is determined by the fact that the fertilizers in an easily accessible form can be introduced at those stages of plant development when they are most required. In this case, a more uniform distribution of fertilizers in the area is provided, the coefficient of their use increases, improves the quality of products, increases yield. In Ukraine there is no production of appropriate equipment for fertimation and S.-G. Manufacturers have to use for this Equipment for foreign production. In 2017-2020, testing equipment for fertigation used by Ukrainian S.-G. Manufacturers: ITL SL, Spain, Inject-O-Mfg.S., Agri-Inject, Inc. » USA. The conducted studies on the introduction of liquid fertilizer CAS showed that the parameters of the dispenser pump and other components of the test equipment provide fertilizers with irrigation water according to their desired norm. The work of the pump-dispenser does not significantly affect the pressure-consuming characteristics of the rainy machine. The use of CAS increases the technological equipment of equipment, reduces energy intensity and labor intensity of its work due to the absence of a technological operation of the preparation of a mother liquor. Conclusions. The established effectiveness of the technological operation of fertility using test equipment allows a steadily process with the appointment indicators, the quality of work and reliability that satisfy the requirements for the technological process of fertilizing with irrigation water.
CONSTRUCTION-TECHNOLOGICAL SCHEME AND PARAMETERS OF EQUIPMENT FOR ULTRASOUND DISINTEGRATION OF PLANT RAW MATERIALS
Authors:   National University of Life and Environmental Sciences of Ukraine, Bratishko V.
Published: December 2021

Purpose of the study. Improving the efficiency of ultrasonic disintegration of plant raw materials based on the search for rational (in terms of ensuring the required level of disintegration of plant raw materials) parameters of the cavitation chamber, properties of the suspension, and processing modes. Research methods. Methods of analysis and generalization of the results of scientific research of the processes of ultrasonic treatment of liquids and suspensions were used to substantiate the rational design and technological scheme and parameters of equipment for ultrasonic disintegration of plant raw materials. The results of the study. Acoustic piezoelectric cavitators with a low (up to 5.0 W/cm2) intensity of ultrasound, which is introduced into the liquid or suspension through the bottom (walls) of an open non-resonant cavitation chamber, are the most suitable for cavitation treatment of aqueous suspensions of plant bioresources. Ultrasonic emitters in this case are rigidly attached to the outside of the bottom (walls) of the cavitation chamber. Based on the analysis of research results, the design of a device for ultrasonic treatment of suspensions of plant raw materials was proposed. Conclusions. It is established that the main parameters determining the efficiency of the process of ultrasonic disintegration of plant raw material suspensions are the presence of an effective layer and rational intensity of ultrasonic influence on the medium in the cavitation chamber, which depends on the physical and mechanical properties of the treated medium. Based on the analysis, a structural and technological scheme of the device for ultrasonic treatment of suspensions is proposed.
STUDY OF SYSTEMS WITH ELECTRODYNAMIC AND ELASTIC CONNECTIONS UNDER HARMONIC EXCITATION
Authors:   L. Pogoriliy Ukrainian Scientific Research Institute of Forecasting and Testing of Machinery and  Technologies for Agricultural Production, Kalinin E. , Korobko A. A.
Published: December 2021

Abstract Purpose of the study is to analyze the operation of a mechanical system with the introduction of electrodynamic and elastic components into it to ensure that the operating modes of the latter go beyond the resonance modes. The tasks of the research involve the synthesis of the mathematical apparatus with the subsequent formation and analysis of the amplitude-frequency characteristics of the specified system. Research methods. The methodological basis of the work is the generalization and analysis of the known scientific results of the dynamics of systems in resonance modes and the use of a systematic approach. The analytical method and comparative analysis were used to form a scientific problem, form a goal and formulate research objectives. When creating empirical models, the main provisions of the dynamics of systems were used. The results of the study. Considering that the dynamic properties of the system depend on the presence or absence of an elastic connection of the transmission line, a combined system was subjected to research. Since it is impossible to obtain an exact analytical solution of the obtained system of nonlinear differential equations, the solution was carried out on an electronic model with harmonic excitation. Based on the results of studies on an electronic model, using the MatLab computer modeling system, it is difficult to establish the influence of the ratio of various parameters, with their possible variations in a large range, on the behavior of the system itself, since a question posed in this way will require a significant amount of computer time. Therefore, a study of the system with harmonious excitation in its linearized form was carried out. Conclusions. A mathematical model of the functioning of a system with electrodynamic and elastic coupling under harmonious excitation has been formed. On the basis of the research carried out, the amplitude-frequency characteristic of the system was built, with the help of which the correspondence of the results of the solution of the electronic (reference), built on the basis of MatLab, and the analytical models was established.
Advances in targeting programmed cell death 1/programmed cell death-ligand 1 therapy for hematological malignancies
Authors:   Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China, Zhao Wanying , Liang Yuanzheng , Wang Liang
Published: December 2021

Programmed cell death 1 (PD-1) and programmed cell death-ligand 1 (PD-L1) are important immune checkpoints, and their interactions can mediate immune suppression in the tumor microenvironment. Targeting PD-1 and PD-L1 are immune checkpoint inhibitors that bind to PD-1 and PD-L1, respectively, to block the signal pathway between the two and increase the immune response. They are widely used in tumor treatment and have good efficacies for malignant melanoma, renal cell carcinoma, and non-small cell lung cancer, among others. In addition, for hematological malignancies, studies targeting PD-1 and PD-L1 have achieved gratifying results. This article briefly reviews the mechanisms of action and clinical and hematological malignancy applications of targeting PD-1 and PD-L1. Keywords: PD-1, PD-L1, mechanism of action, hematological malignancy
SELECTION AND CONSTRUCTION OF THE CONTENT OF EDUCATIONAL MATERIALS OF SCHOOL NATURAL EDUCATION IN THE CONTEXT OF MODERN LEADING EDUCATIONAL PARADIGMS (ON THE EXAMPLE OF STUDYING THE BASES OF THE SPECIAL THEORY OF RELATIVITY AT SCHOOL)
Authors: Martyniuk Mykhailo , Mykolaiko Volodymyr , Pidhornyi Oleksandr , Khytruk Valentyn
Published: December 2021

A brief overview of the results of theoretical and experimental research on the selection and structuring of educational materials in the context of the ideas of humanization and fundamentalization of the content of school science is presented including physical education. The paper shows that when constructing the content of such educational materials, it is necessary to present them in the context of historical development and formation of relevant knowledge, and the proposed content structures provided not only scientific and integrity content of school science education but also the development of the personality of a school-age child.The specific task of this article is to substantiate the new content of teaching the basics of the special theory of relativity in general secondary education and in the methodological system of training future physics teachers. The results obtained in the process of theoretical and experimental research can be used by students of general secondary and higher pedagogical education, graduate students, teachers and methodologists.
Keywords: natural education; personality-oriented content of education; critical thinking; study of the basics of special relativity; expected (predicted) learning outcomes.
Analysis of accidents involved in touring/ sport/ recreational vessels and yachts in the Turkish search and rescue area
Authors: Bayar Sibel , Akan Ercan
Published: December 2021

Our country is surrounded by seas on three sides; it is in an attractive position in terms of tourism due to its suitable climate and many history and cultures. Especially the stagnant structure of the Aegean and the Mediterranean allows sea tourism in almost four seasons; it is one of the routes preferred especially by yacht ships. In this respect, a maritime traffic arises due to touring, sports and recreational ships and yachts, and these ships occasionally cause accidents. In the study, marine accidents in the Turkish Search and Rescue Area involving touring, sports and recreational vessels and yachts are statistically analyzed. In this context, frequency distributions are carried out first and the hypotheses are examined by Chi-Square independence analysis.
Determination of the perception of ship management towards environmental pollion caused by routine operations of ships
Authors: Arslan Osman , Solmaz Murat Selçuk , Usluer Hasan Bora
Published: December 2021

In order to leave a livable world to future generations, the elimination of environmental pollution, which is one of the important dimensions of sustainability, increases its importance every day. Undoubtedly, among the factors that cause environmental pollution, the role of ships is quite high. The seas are also polluted by the routine operation of ships as well as marine accidents. Pollution arising from the routine operations of ships is caused by the discharge of pollutants such as ballast water, bilge water, sludge or garbage into the sea. In addition, emissions from ships and oil and fuel pollution caused by the routine operation of ships also play an important role in environmental pollution. In this study, the phenomena resulting from the routine operations of ships and causing environmental pollution were examined using the Analytical Hierarchy Process (AHP) method, which is one of the multi-criteria decision-making methods, and the perceptions of ship operators towards environmental pollution were tried to be determined.
Effects of chestnut addition on physicochemical composition, total phenolic contents, antioxidant capacities and sensory properties of milk
Authors: Erdoğan Gaye I. , Dündar Ayşe Neslihan
Published: December 2021

Chestnut-added milk (CM) was produced with 2 different methods. In the first method, chestnuts were roasted, and in the second method, they were cooked in bain-marie and then added to milk at different ratios (5, 15, 25 %). The addition of chestnuts to milk statistically increased the amount of protein, dietary fiber, carbohydrate, energy, mineral (Ca, K, P, Mg), antioxidant capacity and total phenolic content compared to the control, whereas it did not cause a significant change in sensory properties. Therefore, the chestnut is a suitable supplementation for milk.
Effects of different ingredients on antioxidant and oxidant status of brewed roasted coffee
Authors: Ertaş Öztürk Yasemin , Ağagündüz Duygu
Published: December 2021

It was aimed to evaluate the effects of different ingredi-ents on total antioxidant sta-tus (TAS) and total oxidant status (TOS) of the brewed Brazil mild roasted coffee. Sugar, sucralose, butter, co-conut-oil, animal and plant-based milk types were add-ed and milk types&sweeteners were combined separately. TAS and TOS were measured and oxidative stress indice (OSI) was calculated. TAS value of coffee with whole milk was the highest among all coffee types. TOS values of coffee with soy milk, with soy milk+sugar and soy milk+sucralose were lower than all other coffee types. When compared to OSI val-ues, coffee with soy milk, with soy milk+sugar and soy milk+sucralose had the lowest OSI values among all coffee types. Moreover, ad-dition of coconut-oil to cof-fee samples increased the TOS and OSI values of cof-fees. While the TOS and OSI of the sugar and su-cralose addition were found higher in comparison to plain coffee; TOS and OSI of the sucralose addition was lower than those sugar combinations. In conclu-sion, the OSI of the coffee may change depending on the alterations of chemical structures and nutritional matrices by the added in-gredients. The addition of soy milk or sucralose in-stead of sugar or whole cow milk instead of oil-based ingredients could be a promising strategy of reduc-ing the oxidative capacity.
Changes in haematological parameters in hens under short-term exposure to adverse environmental factors
Authors: Osadcha Yuliia
Published: December 2021

Short-term exposure to adverse factors is a common phenomenon in industrial egg production. An urgent problem is to understand the impact of environmental changes on poultry use. A comparative analysis of changes in haematological parameters in hens under short-term exposure to adverse environmental factors of different natures was performed. For this purpose, a control and 3 experimental groups of hens were established in a modern complex for the production of food eggs. Within 24 hours, the hens of the 2nd group were deprived of fodder, the 3rd group – of light, and the 4th group – were kept in significant overcrowding. The smallest changes in the blood system of hens were observed under the influence of the factor of lack of fodder, namely an increase, within the physiological standard, in the content of leukocytes and erythrocyte sedimentation rate, a decrease in haemoglobin concentration, hematocrit, erythrocytes, platelets, and a violation of the ratio of different forms of leukocytes – an increase in the concentration of heterophils (3.3%>normal) against a decrease in the concentration of monocytes (1.6%<normal), lymphocytes and basophils. Therewith, under the influence of the factor of the absence of light, a higher content of leukocytes in the blood by 10.6%, a lower concentration of haemoglobin by 22.4%, hematocrit – by 4.2%, platelets – by 9.8%, and a higher erythrocyte sedimentation rate by 9.8%, a higher concentration of heterophils by 5.9% and a lower concentration of lymphocytes – by 4.6% were identified compared to the factor of the absence of fodder. The most significant changes in the blood system were noted under the influence of the factor of significant over-consolidation of hens, namely, a higher content of leukocytes in the blood by 17.1 and 5.9%, a lower concentration of haemoglobin by 29.6 and 9.2%, hematocrit – by 5.9 and 1.7%, erythrocytes – by 10.3%, platelets – by 35.8 and 28.8%, and higher erythrocyte sedimentation rate by 4.9%, a higher concentration of heterophils by 11.3 and 5.4 % and lower concentration of monocytes by 0.8 and 0.4%, lymphocytes by 9.4 and 4.8% and eosinophils by 0.7% compared to the factor of lack of fodder and lack of light, respectively. Thus, in production conditions, it is necessary to avoid the over-compaction of poultry, as this factor has the greatest adverse effect
Thermic Characteristics Of Rice Husk And Polyurethane Composite Materias As Insulation In Fish Cold Storage
Authors: Irwansyah  , Balkhaya  , Fitriadi Nuzuli , Susanto Herdi
Published: December 2021

The process of freezing fish always requires a cooler as a temporary storage place for fish. The ability of the storage to maintain cold temperatures is a serious problem to be considered so that the freshness of the fish can be maintained. Therefore, an appropriate technology is required to support the cold chain system so that fish quality can be maintained. The purpose of this study was to test the thermal conductivity of composite materials for fish storage insulation from a mixture of rice husks and polyurethane so that the price of the box can be reduced but still maintain the quality of the fish. The composition of the composite material was made with a volume ratio of 1:0.5, 1:1, 1:1.5, and 1:2. The thermal conductivity test of the material uses the ASTM E1225-99 standard. All test results were compared with 100% polyurethane material. The results of testing the thermal conductivity of 100% polyurethane material obtained 0.023 W/m.C. From all the test results, the material that is most likely to be applied to fish cooler box insulation is a 1:1 composition having a thermal conductivity value of 0.067W/m.C. Materials with this composition do not affect the expansion of the polyol and isocyanate reactions. This composition is the most economical to be used as insulation for fish storage boxes which can save the use of polyurethane by 50%.
Syringocystadenoma Papilliferum at an Unusual Location: a Case Report
Authors: Gulanikar Anirudha , S. Kulkarni Omkar
Published: December 2021

A case of 15year old female presented with lesion over back since childhood, with occasional bleeding and oozing from lesion without any associated systemic complaints. There were multiple verrucous coalescing papules forming plaque with overlying erosion present over left lower back- diagnosed provisionally as angiokeratoma circumscriptum and was biopsied. Histopathology revealed findings consistent with Syringocystadenoma papilliferum. Surgical excision was done and closed with rotation flap. Syringocystadenoma is benign cutaneous adnexal tumor presenting clinically with many morphologies such as warty papules, nodules, plaques with oozing of serous material. Lesion is usually seen in head and neck area in most cases however can also occur on extremities, buttocks, anogenital region. It is characterized by multiple invaginations from skin surface in association with hair follicles lined by cuboidal to columnar epithelium on luminal aspect and myoepithelial cells on outside. There is papillary architecture and dermal ductal component.
The Psychosocial Impact of Rosacea in Men: First Quantitative Study
Authors: S Al Abadie Mohammed , Asharaff Farlin , Al Abadie Dina
Published: December 2021

Psychosocial impact of Rosacea in men has generally been a topic that in understudied in literature. We conducted a cross-sectional paper-based survey was conducted with male patients who have experienced rosacea for at least five years at the dermatology outpatient department at New Cross Hospital in Wolverhampton, England to determine the psychosocial impact of Rosacea on Men Quality of life and self-esteem. 52 % of the male population were noted to be “often” mentally pre-occupied by rosacea and frustrated due to rosacea. 85 % of the male population “never” used cosmetic camouflage. Mean function score is noted to be 6.81. This indicates that men are less in favour of coping mechanisms. Results from this study highlight that despite the emotional impact rosacea has on the male population, they do not frequently use coping mechanisms. This emphasises the psychosocial impact of rosacea on male population and the need for dermatologists to address the emotional impact on men as part of management as well as to raise awareness around this topic.
Case report of a de novo mutation of PCDH19 in Saudi family limited to females
Authors: Alsheikh Rawan , Al-Qassmi Amal
Published: December 2021

Up to date more than 60 different mutations in PCDH19 have been identified. Most of PCDH19 gene is located in Xq22 and produces nonclustered delta protocadherin. This disorder primarily manifests in heterozygote females due to random X chromosome inactivation leading to somatic mosaicism and abnormal cellular interference between cells with and without delta-protocadherin., but we a heterozygous nucleotide mutation causing amino acid 561 to change from Pro to Ser (p.Pro561Ser). This mutation was de novo, and this alteration was not found in her parents. PCDH19-related epilepsy is a distinct childhood-onset epilepsy syndrome characterized by brief clusters of febrile and afebrile seizures with onset primarily before the age of three years, cognitive impairment, autistic traits, and behavioral abnormalities. We describe the features of a de novo mutation in 3 sibling, presented with early onset of seizure, two of them were controlled and wean off medication was at age of six year and her sister at age of 10 year .The youngest sister still partially controlled on medication, she had seizure only during febrile illness.
A Girl from Qatar with Post-Infantile Acquired Cerebral Palsy Caused By Submersion Injury: A Rare Etiology and a Therapeutic Challenge
Authors: Jalal Al-Mosawi Aamir
Published: December 2021

Background: Cerebral palsy is a heterogeneous disorder that can cause a lifelong disability that is associated with a non-progressive damage in the brain. It is commonly caused by antenatal, perinatal, early postnatal and neonatal conditions. However, post-neonatal cases of acquired cerebral palsy have also been reported, and were commonly caused by infection. Patients and methods: The family of a girl from Qatar, who developed severe cerebral palsy caused by submersion injury, consulted us about the possible therapies for her condition. Clinical picture and brain imaging abnormalities are described, and the relevant literatures were reviewed with the aim of suggesting possible evidence-based therapies. Results: At the age of 23 months, a previously healthy girl developed anoxic encephalopathy after experiencing submersion injury. MRI showed evidence of significant hypoxic ischemic injury primarily affecting the deep grey matter, hippocami, mid-brain and the posterior cortex. EEG showed diffuse slowness of cerebral activity and diffuse attenuation of the background without no epileptic abnormalities suggesting diffuse encephalopathy resulting from diffuse cortical injury. At the about age of three and half years, her family consulted us about her condition as she was still showing no awareness to the environment, showing no significant spontaneous movements. She had poor head control. Unable to sit or stand alone, and had a flexed posture. She was on levetiracetam (Keppra), diazepam, and baclofen 30 mg daily. She was still having tracheotomy, and was fed through gastrostomy tube. Conclusion: In this paper, the rare occurrence of severe post-infantile cerebral palsy is described. Emphasis is made on the possibility of using evidence-based multi-factorial therapies in cerebral palsy.
Clinical Pharmacology of Levetiracetam in Infants and Children
Authors: Pacifici Gian Maria
Published: December 2021

Levetiracetam inhibits focal and secondary generalized tonic-clonic seizures. The mechanism of levetiracetam action is not fully understood, however the correlation between binding affinity of levetiracetam and its analogues and their potency toward audiogenic seizures suggest that the synaptic vesicle glycoprotein 2A mediates the anticonvulsant effects of levetiracetam. The neural function of the synaptic vesicle 2A protein is not fully understood, but binding of levetiracetam to synaptic vesicle glycoprotein 2A might affect neuronal excitability by modifying the release of glutamate GABA through an action on vesicular function. Synaptic vesicle glycoprotein 2A may plain a role in vesicle recycling following exocytosis of neurotransmitter. In addition, levetiracetam inhibits N-type Ca2+ channels and Ca2+ release from intracellular stores. Levetiracetam may be administered intravenously or orally to infants and children and in children the levetiracetam dose varies according to the child age and body-weight. Levetiracetam is almost completed absorbed after oral administration and levetiracetam is found efficacy and safe in infants and children but it may induce adverse-effects. The levetiracetam elimination half-life is about 6 hours in infants and children, and in children the renal clearance is similar to the non-renal clearance. The prophylaxis, treatment, and trials with levetiracetam have been extensively studied in infants and children. Levetiracetam freely crosses the human placenta and freely migrates into the breast-milk. The aim of this study is to review the levetiracetam dosing, efficacy, safety, adverse-effects, pharmacokinetics, prophylaxis, treatment, and trials and transfer of levetiracetam across the human placenta and levetiracetam migration into the breast-milk.
Diagnosis and Management of Infected or Suspected Patients with Covid-19 a Study of 48 Cases in the UK
Authors: Jiang Dan
Published: December 2021

Covid-19 is a pandemic infective disease, which has been erupting throughout the whole world from 2020 to 2021. There have been at the time of reviewing more than a hundred million cases (102,399,513) of infection, and more than 2 million deaths (2,217,005) in more than 200 countries; this information is taken from the Covid-19 daily situation report issued on 1st Feb 2021 by WHO. The pandemic was also declared as an outbreak of Public Health Emergency of International Concern on 30th Jan 2020 by WHO. No effective treatment model has yet been confirmed by conventional western medicine, but some herbal treatments used in China can be recognized as having positive results in Covid-19 cases. This pandemic disaster has been severely damaging to quality of life, disturbing social communication, economic development and the progress of humanity. Successful results were first reported from temporary hospitals (Fangcang Hospitals set up in arenas and exhibition spaces) in Wuhan, China, where more than 90% of patients treated with Chinese herbal medicine were prevented by transferring from the minor or milder stages of the disease to the severe or critical stage. In all of them the positive PCR became negative; herbs were involved in the rescue and treatment of severe and critical cases in ICU’s in hospitals as well. It was an important factor in how Covid-19 was controlled so quickly in China. The author recruited both confirmed and suspected Covid-19 patients through social media (WeChat, WhatsApp, Internet, message etc.) as a volunteer TCM consultant from March 2020, during the first Lockdown phase in UK. It was quickly realized that the appearance of the tongue provides special and significant information for identifying whether Covid-19 is present and shows its severity, from a TCM perspective, as the degree and type of dampness accumulated within the body. Herbal prescriptions were sent by post for patients’ treatment according to their clinical findings, virus exposure history and tongue information (from photos). Similar positive effects were found as in China, and treatment reports and results are summarized here. The author believes there are many herbal medicines that can be effective in controlling the Sars-Cov-2 virus, and that prescribing the appropriate formula to match each individual case is the key point for TCM control of Covid-19. Chinese herbal medicine is the most effective current treatment method that can prevent cases in the minor and ordinary stages from progressing to the severe or critical stage, and so can play a significant role in the decrease and cure of Covid-19.
Personal Digital Health Assistants
Authors: Jain Uday
Published: December 2021

Personal Digital Health Assistants (PDHA) are applications that can run on virtually any computer or mobile device including a smart phone/ personal digital assistant (PDA). A PDHA acquires, stores, and analyzes health related information of an individual. It usually communicates with remote servers of a large organization which can connect it to various resources. PDHAs are an integral part of telehealth. Their utility has increased manyfold since the start of the pandemic. The systems are increasingly more complex and are involved in all aspects of care. The PDHA are usually utilized by patients or their caregivers with assistance from professionals. Many automated systems can be utilized free of charge. Some are available as part of a prepaid health plan.
Technical Intricacies Involved in Surgical Retrieval of a Long Standing Foreign Body in Hand- A Case Report
Authors: S M Narendra
Published: December 2021

Foreign Bodies (F.B) are not uncommon in hand as it is involved in Day to day activities. Prompt removal during the initial examination is the norm, but sometimes foreign bodies (F.B) may be missed and they remain within the soft tissue for a long time either revealing itself at a later date as a sinus, swelling or an abscess. We present a case of retained FB in the dorsum of hand and the technique involved in retrieval of such a long standing FB.
Virus Sir-Learning Experience in the Pandemic
Authors: Farooq Baba Umar
Published: December 2021

The COVID-19 pandemic changed us individually as well as our routines, goals, and motives. Rightly so, some changes may last longer. Importantly, the pandemic has made us understand several lessons, and has tried to enhance our positive perspective regarding life and its requirements. We came to know how quickly we are capable of adapting to changes. These adjustments proved beyond doubt that there’s not much in life that is truly indispensable. We are practising self-care in a multitude of ways. We might not have thought of our power of resilience. Again, mental health took over as an epicentre of overall wellbeing, reminding us of the power of ‘mind matters’ over ‘money matters’. The health sector disparities and unpreparedness to combat any sort of pandemic situation surfaced not only in resource-limited countries like ours but the uneasiness of the developed world became exposed. The pandemic had been a harsh learning experience for all of us, irrespective of our position in the spectrum.