bluuebunny/crossref_metadata_2025 huggingface dataset:
Lophiostomin A–D: new 3,4-dihydroisocoumarin derivatives from the endophytic fungus Lophiostoma sp. Sigrf10
Authors: Mao Ziling , Xue Mengyao , Gu Gan , Wang Weixuan , Li Dianpeng , Lai Daowan , Zhou Ligang
Published: February 2020

Four new 3,4-dihydroisocoumarin congeners, named lophiostomin A–D (1–4), together with two known α-pyridones (5 and 6) were isolated from cultures of the endophytic fungus Lophiostoma sp. Sigrf10 obtained from Siraitia grosvenorii.
An oscillatory plug flow photoreactor facilitates semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings
Authors: Rosso Cristian , Gisbertz Sebastian , Williams Jason D. , Gemoets Hannes P. L. , Debrouwer Wouter , Pieber Bartholomäus , Kappe C. Oliver
Published: February 2020

Dual nickel/photocatalytic C–N couplings are performed with an organic heterogeneous photocatalyst, in an oscillatory plug flow reactor. Reaction was complete in 20 min residence time, enabling 2.7 g h−1 throughput and 10-fold catalyst recycling.
Coarse-grained Monte Carlo simulations of nanogel–polyelectrolyte complexes: electrostatic effects
Authors: Pérez-Mas Luis , Martín-Molina Alberto , Quesada-Pérez Manuel
Published: February 2020

Coarse-grained model of nanogel–polyelectrolyte complex.
Reply to Comments on ‘A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus’
Authors: Huang Bo , Wang Yu-kun , Qin Lin-yuan , Wei Qin , Liu Nian , Jiang Min , Yu Hong-ping , Yu Xiang-yuan
Published: February 2020

Th authors of ‘A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus’ (Bioscience Reports (2019) 39, 12) have written a reply in response to the correspondence piece by Rosta et al. (Bioscience Reports (2020) 40, 2).
Comparative study of channel estimators for massive MIMO 5G NR systems
Authors: Carrera Diego Fernando , Vargas‐Rosales Cesar , Azpilicueta Leyre , Galaviz‐Aguilar Jose Alejandro
Published: February 2020

In this work, a comparative analysis is performed to study the bit error rate and error vector magnitude achieved with the least‐squares (LS), the minimum mean squared error (MSE), and the Kalman filter (KF) channel estimators when these are applied to the maximum‐ratio combining (MRC) and the regularised zero‐forcing (RZF) receivers. The MSE achieved with the different channel estimators was also compared by varying the noise and interference power at the receiver. The proposed methodology relies on the characterisation of a massive multiple‐input multiple‐output (MIMO) channel with a quasi‐deterministic radio channel generator and a cyclic prefix orthogonal frequency division multiplexing link‐level radio simulation. The fifth‐generation (5G) new radio (NR) frame structure was used to perform channel estimation and equalisation for operation frequencies below 6 GHz. Numerical results show that the MRC receiver achieves its maximum performance with the KF estimator, especially at low signal‐to‐noise ratio scenarios, while the RZF receiver achieves its maximum performance with the LS estimation even in high interference scenarios.
Stabilisation of event‐triggered‐based neural network control system and its application to wind power generation systems
Authors: Shanmugam Lakshmanan , Mani Prakash , Joo Young Hoon
Published: February 2020

This study addresses the event‐triggered (ET)‐based stabilisation problem of neural‐network‐based control system (NNBCS) and illustrates the direct application to wind power generation system. In this regard, the novel ET‐based controller algorithm is designed for NNBCS instead of sampled data controller (sampling will be initiated at a fixed rate regardless whether it is required or not) which reduces the computation complexity by avoiding the unnecessary details over the transmission. The novel stability and stabilisation conditions are expressed in terms of linear matrix inequalities that are derived through constructing the time‐dependent Lyapunov functional candidate. For deepening the knowledge in the outcomes of the proposed conditions, the study numerically evaluates the dynamic models such as variable‐speed wind turbine drive system, permanent magnet synchronous motors model and traditional inverted pendulum model and validates the effectiveness of the proposed controller scheme. Finally, a comparison result shows the superiority of the derived conditions.
Magnetic field‐modulated linear permanent‐magnet generator for direct‐drive wave energy conversion
Authors: Feng Ningjun , Yu Haitao , Zhao Mei , Zhang Ping , Hou Dianli
Published: February 2020

The linear permanent‐magnet synchronous generator (LPMSG) for direct‐drive wave energy conversion (WEC) suffers from many drawbacks that have not yet been overcome, such as a low power density and a bulky system volume. Therefore, a magnetic field‐modulated linear permanent‐magnet generator (FMLPMG) with a simple structure has been designed and manufactured. First, the operating principle of the FMLPMG is demonstrated by the equivalent magnetic circuit method, which explains the high power density of the FMLPMG. Second, at a constant speed and a sinusoidal speed, the electromagnetic characteristics of the FMLPMG under the no‐load and load conditions are analysed by the finite‐element method. Finally, a direct‐drive WEC test platform is built to simulate the process of wave action on the FMLPMG. No‐load and load experiments of the FMLPMG are conducted on the test platform, and the results are compared with those of an LPMSG with the same volume and operating conditions. The results show that the FMLPMG with a high power density converts wave energy effectively and solves the problem of low power density faced by the LPMSG in direct‐drive WEC.
Lane‐changing trajectory planning method for automated vehicles under various road line‐types
Authors: Wang Ying , Wei Chong , Liu Erjian , Li Shurong
Published: February 2020

This study proposes a lane‐changing trajectory planning method for automated vehicles under various road line‐types. The method uses the polynomial regression model to describe the road line‐types, and then a non‐linear optimisation model is constructed to generate the lane‐changing trajectory based on the road polynomial functions. The process of connecting the lane‐changing manoeuvre with the car‐following manoeuvre is discussed in this study, which ensures the ride comfort of the ego vehicle after the lane‐changing manoeuvre. Moreover, considering that the lag vehicle on the target lane may be affected by the lane‐changing manoeuvre, the situation that the lag vehicle maintains the car‐following manoeuvre with the ego vehicle is taken into account in the authors’ model. Another small innovation is that they have designed a simple and effective method to find the suitable initial guess for the proposed non‐linear optimisation model. The simulation results show that the lane‐changing trajectory generated by the proposed model is smooth and continuous, and the automated vehicle can avoid potential collisions efficiently during the lane‐changing process. In emergent conditions, the proposed model can also plan the corrected trajectory to ensure safety.
Selection of highly-accreting quasars
Authors: Bon N. , Marziani P. , Bon E. , Negrete C. A. , Dultzin D. , del Olmo A. , D’Onofrio M. , Martínez-Aldama M. L.
Published: February 2020

Context.The quasar class of extreme Population A (xA) (also known as super-Eddington accreting massive black holes, SEAMBHs) has been hailed as potential distance indicators for cosmology.

Aims.The aim of this paper is to define tight criteria for their proper identification, starting from the main selection criterionRFeII >  1, and to identify potential intruders that do not meet the selection criteria, which nonetheless have been selected as xA because of the coarseness of automatic searches. The inclusion of the spurious xA sources may dramatically increase the dispersion in the Hubble diagram of quasars, which were obtained from virial luminosity estimates.

Methods.We studied a sample of 32 low-zquasars that were originally selected from the seventh data release of the Sloan Digital Sky Survey as xA or SEAMBHs, which have been proved to be almost certainly misclassified sources. All of them show moderate to strong Fe IIemission and the large majority show strong absorption features in their spectra which are typical of fairly evolved stellar populations. We performed a simultaneous fit of a host galaxy spectrum, active galactic nucleus (AGN) continuum, FeII template, and emission lines to spectra, using the fitting technique based onULySS, the full spectrum fitting package. We derived the main accretion parameters (i.e., luminosity, black hole mass, and Eddington ratio) and investigate the relation between host galaxy properties and AGN.

Results.For sources in our sample with spectral types that correspond to a relatively low Eddington ratio, we find an overall consistency between HβNC, [O III]λλ4959,5007 line shifts, and the mean stellar velocity obtained from the host galaxy fit (within ≲|60| km s−1). Only one source in our sample qualifies as a xA source.

Conclusions.The correct classification of spectra that were contaminated by heavy absorption requires careful determination of the host galaxy spectrum. Contamination and misclassification are not usual in the identification of the xAs, nor at lowzor at highz. We find a high fraction of host galaxy spectrum; in half of the sample this is even higher than 40%. When absorption lines are prominent, and the fraction of the host galaxy is high, host galaxy spectrum mimics FeII, which may result in a mistaken identification of FeII spectral features. We have identified several stellar absorption lines that, along with the continuum shape, may lead to an overestimate ofRFeII, and therefore to the misclassification of sources as xA sources.
ISPY-NACO Imaging Survey for Planets around Young stars
Authors: Launhardt R. , Henning Th. , Quirrenbach A. , Ségransan D. , Avenhaus H. , van Boekel R. , Brems S. S. , Cheetham A. C. , Cugno G. , Girard J. , Godoy N. , Kennedy G. M. , Maire A.-L. , Metchev S. , Müller A. , Musso Barcucci A. , Olofsson J. , Pepe F. , Quanz S. P. , Queloz D. , Reffert S. , Rickman E. L. , Ruh H. L. , Samland M.
Published: February 2020

Context.The occurrence rate of long-period (a≳ 50 au) giant planets around young stars is highly uncertain since it is not only governed by the protoplanetary disc structure and planet formation process, but also reflects both dynamical re-structuring processes after planet formation as well as possible capture of planets not formed in situ. Direct imaging is currently the only feasible method to detect such wide-orbit planets and constrain their occurrence rate.

Aims.We aim to detect and characterise wide-orbit giant planets during and shortly after their formation phase within protoplanetary and debris discs around nearby young stars.

Methods.We carry out a largeL′-band high-contrast direct imaging survey for giant planets around 200 young stars with protoplanetary or debris discs using the NACO instrument at the ESO Very Large Telescope on Cerro Paranal in Chile. We use very deep angular differential imaging observations with typically >60° field rotation, and employ a vector vortex coronagraph where feasible to achieve the best possible point source sensitivity down to an inner working angle of about 100 mas. This paper introduces the NACO Imaging Survey for Planets around Young stars (NACO-ISPY), its goals and strategy, the target list, and data reduction scheme, and presents preliminary results from the first 2.5 survey years.

Results.We achieve a mean 5σcontrast of ΔL′ = 6.4 ± 0.1 mag at 150 mas and a background limit ofL′bg= 16.5±0.2 mag at >1.′′5. Our detection probability is >50% for companions with ≳8MJupat semi-major axes of 80–200 au and >13MJupat 30–250 au. It thus compares well to the detection space of other state-of-the-art high-contrast imaging surveys. We have already contributed to the characterisation of two new planets originally discovered by VLT/SPHERE, but we have not yet independently discovered new planets around any of our target stars. We have discovered two new close-in low-mass stellar companions around R CrA and HD 193571 and report in this paper the discovery of close co-moving low-mass stellar companions around HD 72660 and HD 92536. Furthermore, we reportL′-band scattered light images of the discs around eleven stars, six of which have never been imaged atL′-band before.

Conclusions.The first 2.5 yr of the NACO-ISPY survey have already demonstrated that VLT/NACO combined with our survey strategy can achieve the anticipated sensitivity to detect giant planets and reveal new close stellar companions around our target stars.
Modeling using experimental design method of the physicochemical parameters of the water quality in Meknes city, Morocco
Authors: Bouazza Ghariba , Assou Mohammed , Souabi Salah , Chatri El Houssine
Published: February 2020

This study was focused on the characterization of physicochemical parameters of drinking water, which are mainly involved during water treatment or analysis processes. we were interested in the application of the experimental design methodology, according to the method of Yates on the parameters that characterize the quality of drinking water in Meknes, Morocco. Six factors have been identified to control this quality. The influence of these parameters on the responses accommodated at the exit was highlighted. The derivation of a theoretical model has been realized and a series of experiments was performed. The analysis of our results, based on a statistical approach, was presented and the parameters that have a significant influence on the outputs have been identified. From these results, we can conclude that the input factors such as hardness, pH, conductivity, residual chlorine and turbidity have a large influence on measured output response (pHs). Moreover, the theoretical and experimental results are very convergent which validate our studied model.
Estimation of greenhouse gas (GHG) emissions from natural lagoon wastewater treatment plant: Case of Ain Taoujdate-Morocco
Authors: Bahi Yassine , Akhssas Ahmed , Khamar Mohamed , Bahi Lahcen , Souidi Hanane
Published: February 2020

The process of removing organic components from wastewater as BOD5 through wastewater treatment plants has been proven to be a significant source of greenhouse gas emissions, mainly methane CH4, carbon dioxide CO2 and nitrous oxide N2O. The reduction of these emissions has attracted more interest given their major contribution to global warming. This study was able to identify and estimate the amount of methane and CO2 emissions on a monthly basis by a simple modeling approach and an empirical method (IPCC) for N2O emissions, in the case of Ain-Taoujdate wastewater treatment plant, throughout the years 2013, 2018 and 2019. The results showed that anaerobic ponds were the main source of on-site emissions with 66% of total contribution and 33% for facultative ponds, followed by the energy consumption of the pumping station as off-site GHG emissions.
Impact of anthropogenic actions on the quality of the Maâmora groundwater (Tiflet city region)
Authors: Qoutbane Anass , Cherkaoui Essediya , Khamar Mohamed , Nounah Abderrahman
Published: February 2020

The quality of groundwater in and around the city of Tiflet depends mainly on the various anthropogenic impacts on ecosystems where the Maamora groundwater in this region is subject to liquid discharges from the city of Tiflet from Oued Tiflet and infiltration of leachate from the uncontrolled landfill. With the ultimate aim of considering the necessary solutions and ensuring the means of protecting water resources and sustainable development of the Tiflet region, the study of the physical, chemical and bacteriological quality of groundwater (Maamora groundwater) from the city of Tiflet to the centre of the commune of Sidi Boukhelkhal, which is located north-west of the city and on the banks of Oued Tiflet, is the first step. These results are processed by ArcGis software and presented by interpolation maps. The bacteriological characterization of groundwater shows that it is not drinkable but acceptable for agricultural use, however, physico-chemical parameters such as nitrates and sulphates remain below the quality standards for human consumption. Turbidity, pH and conductivity vary according to space but also do not exceed quality standards in irrigation and human consumption.
Seismic analysis of the zaouiat ait mellal twin tunnels of Agadir motorway (Morocco)
Authors: El Omari Abdelhay , Chourak Mimoun , Ugena Carlos Navvaro , Cherif Seif-Eddine , Rougui Mohamed , Bakali Hassan , Sanchez-Merino Angel luis
Published: February 2020

Underground structures, such as tunnels, are vital for ensuring all kinds of transportation; and being buried under the surface makes them exposed to soil dynamics. Added to the moderate seismic activity in Morocco, the stability of tunnels is put to the test. This paper examines the interaction between the ZAM (Zaouit Ait Mellal) twin tunnels between the cities of Marrakesh and Agadir, using the Difference Element Method provided by FLAC 2D software. The acceleration is introduced as the one related to the historic event of El centro 1940 with free-field boundary conditions in the numerical model, with three configurations: tunnel 1 without tunnel 2, tunnel 2 without tunnel 1 and tunnel 1 with tunnel 2. The results of the simulations indicate that the differences values of the maximum displacement, axial force and bending moment on structural elements are very noteworthy from the configuration of the tunnel (single) to the twin tunnels in order to prove the interaction between these latter under seismic loading.
The correlation between spermatozoa morphometry and the testosterone levels in the epididymis of aceh cow
Authors: Wahyuni Sri , Gholib Gholib , Maulana Rizki , Dasrul Dasrul , Siregar Tongku N. , Hamny Hamny , Jalaluddin Muhammad , Gani Fadli A. , Ritonga Mudhita Z. , Akmal Muslim
Published: February 2020

The objective of this study was to determine the correlation between spermatozoa morphometry and testosterone concentration in the epididymal caput, corpus, and cauda of aceh cattle. The epididymal sperm swab slides were stained using Williams's staining to examined the morphology and morphometry of spermatozoa whereas the level of testosterone from epididymal caput, corpus, and cauda extract was measured using enzyme-linked immunosorbent assay (ELISA). The data of sperm morphology were presented descriptively whereas the data of sperm morphometry and testosterone concentration were analyzed using one way ANOVA. Pearson correlation test was conducted to know the correlation between the total length of spermatozoa (TLS) and testosterone concentration in three parts of epididymis. The result showed that the sperm morphology in caput, corpus, and cauda of epididymis was not different statistically. The TLS of aceh cattle at caput, corpus, and cauda epididymis were 69,70±0,8 µm, 70,90±0.39 µm, and 72,98±0.74 µm respectively and statistically different (p<0.05). In addition, the concentration of testosterone in caput, corpus, and cauda epididymis were 9,92±3,76 ng/g, 16.96±13,22 ng/g, and 15,63±11.80 ng/g respectively and also not different among three parts of epididymis (p>0.05). The positive correlation (r= 0.413, p= 0.416) was found between TLS and testosterone concentration at caput whereas in corpus and cauda those correlation were negative and not different (corpus: r= -0.638, p= 0.172 and cauda: r= -0.719, p= 0,108). In conclusion, the longest-sized spermatozoa found in the cauda epididymis are mature spermatozoa where the maturation process optimally takes place in caput epididymis. Testosterone found in the epididymis of aceh cow can be used as an alternative source of testosterone.
Distribution of Insect Species as An Indicator for Determining Durian Tree age in Pulo Seunong Plantations, Tangse-Pidie
Authors: Mufti Rifki , Sarong Muhammad A. , Khairil Khairil , Safrida Safrida , Sayuthi Muhammad
Published: February 2020

Insects are the dominant animal group on earth with nearly 80 % species of the total animals on the surface. Insects are often found on plantation land such as durian plantations. Durian plants are visited by insects for various purposes such as helping pollination and collecting finding food. This research was focus on the distribution of insect species as an indicator to determine the age of the Durian Tree in the Pulo Senang Plantation, Tangse-Pidie. The purpose of this study was to determine the distribution of indicator insect species based on the age of Durian Tree. This research was conducted in several Durian tree plantations in Pulo Seunong, Pidie from November to October 2017. The method used in this research surveys with random purposive sampling technique. Data were analyzed quantitatively. The results showed that the distribution of insects species found in this study was distributed in 3 parts of durian, namely the root, the stem, and the leaf. The most dominant insect found in the range 0-5 years old, 6-10 years old, and more than 11 years old durian tree were. the species was found on that range age is Solenopsis invicta species (39%), Dolichoderus thoracicus (33%), Coponatus sp (29%).
Deviation of Body Weight Estimation using Lambourne Formula Against Aceh Bull’s Actual Body Weight
Authors: Hasan Muhammad , Lubis Utari D.M. , Meutia Nellita , Hambal Muhammad , Gani Fadli A. , Masyitha Dian
Published: February 2020

This study aims to determine the percentage of body weight deviation of Aceh bull using the Lambourne formula and compared to the actual weight of Aceh bull. The sample used in this study was 50 Aceh bull aged 2-2.5 years in BPTU-HPT Indrapuri Aceh. The parameters observed were Body Length (BL), Chest Circumference (CC), and Body Weight (BW). BL measurement procedure was conducted by measuring the distance between the lateral humeral tuberculum to the ischiadium tuberculum using a measuring stick. CC was measured by encircling the chest cavity which is behind the shoulder bone joint (os scapula) using measuring tape. BW measurement procedure was carried out in two ways, first with digital livestock scales and second with Lambourne formula. The percentage of body weight deviation of Aceh bull using Lambourne formula to the actual’s Aceh bull body weight was 3.41% with regression equation was Y = -350.30 + 2.27x1 + 2.06x2.
Efficacy of Jatropha curcas Latex Cream in The Epithelialization Phase of Wound Healing in Mice Skin
Authors: Salim Muhammad N. , Silvia Moma , Aliza Dwinna , Masyitha Dian , Iskandar Cut D. , Rusli Rusli , Sugito Sugito , Hasan Muhammad , Sabri Mustafa , Harris Abdul
Published: February 2020

The objective of the present research was to find out the efficacy of Jatropha latex cream in the epithelialization phase of wound healing in mice skin. A total of 9 male mice aged 2-3 months old and the bodyweight of 25-40 g were divided into three treatment groups. Group A was given basic cream, group B was given Jatropha latex cream (10%), and group C was given sulfadiazine. The 2 cm incision wound was made in the paravertebral area. Wound therapy was carried out twice a day for 7 days. All quantitative data were measured using ANOVA then followed by the Duncan test. The number of angiogenesis on A, B, and C was 4.67±1.20; 12.78±2.52; and 11.33±2.33, while a number of fibroblasts were 179.56±12.69; 90.56±8.23; and 99.11±7.04, respectively. The average deposition of collagen was 1.46±0.12; 1.89±0.10; and 1.74±0.06, respectively. The statistical test showed that the number of angiogenesis, fibroblast, and deposition of collagen on group B was significantly different (P<0.05) compared to group A and showed no significant difference compared to group C (P>0.05). In conclusion, Jatropha latex cream (10%) able to accelerate the epithelialization phase of wound healing in mice skin.
Anthelmintic Activity of Curcuma Aeruginosa Roxb Extract on Fasciola gigantica in Vitro
Authors: Vanda Henni , Parindra Rizki , Hambal Muhammad , Athaillah Farida
Published: February 2020

Fasciola gigantica is a parasite that causes a disruption of the metabolism of fats, proteins, and carbohydrates, which interferes growth and causes death. Curcuma aeruginosa Roxb extract is one of the medicinal plants which has been used to treat several diseases. The aim of this study was to determine the effect of methanolic extract of C. aeruginosa Roxb on F. gigantica, including mortality time and histopathological changes that occurred after treatment. This study used a completely randomized design with five replications. The flukes were soaked in three different extract concentrations: 10% (T1), 25% (T2), and 50% (T3) (w/v). Phosphate buffered saline (PBS) solution was used as a negative control (C1) and albendazole as the positive control (C2). The mortality time of F. gigantica in each group was calculated, and the dead flukes were prepared for histopathological study. The data were analyzed by Analysis of variance. The results showed that C. aeruginosa extracts at the concentration of 10, 25 and 50% caused the death of the flukes within 75, 57 and 48 minutes, respectively., Histopathological observations showed that the extract caused breakage of tegument which is an important organ in the respiratory process and nutrient absorption. This study concluded that C. aeruginosa extract exhibited anthelmintic activity towards F. gigantica in vitro.
Effect of Kepok Banana Peel Extract (Musa spp.) on the Number of Pituitary Basophil Cells in Rats (Rattus norvegicus) with High-Fat Diet
Authors: Usrina Nora , Akmal Muslim , Rinidar Rinidar , Sabri Mustafa , Gholib Gholib
Published: February 2020

Banana peels are the outer envelopes of banana fruits as the by-product of household consumption and banana processing. Kepok banana peel contains bioactive compounds that function as antioxidants which reduce the effects of free radicals. This research was conducted to determine the effect of giving Kepok banana peel extract on the number of basophilic cells in rats with a high-fat diet. The study used 25 male rats aged 2.5-3 months old, which alloted into 5 groups with 5 rats each. The first group was fed on standard feed (K1, positive control), while the second group given high-fat diet (K2, negative control). The rats in group 3, 4, and 5 were given high-fat diet + vitamin C (K3), high-fat diet + 100 mg/kg BW banana peel extract (K4), and high-fat diet + 200 mg/ kg BW banana peel extract (K5), respectively. A sample of the pituitary gland was collected after 60 days of the treatment. The data were analyzed using one way analysis of variance (ANOVA) followed by the Duncan test. The results of this study indicated that the administration of Kepok banana peel extract at a dose of 100 mg/kg BW can maintain the number of basophilic cells, whereas at dose of 200 mg/kg BB has the potential to reduce the number of basophilic cells in rats fed high-fat feed.
Preliminary study of new load shedding method considering LFC control
Authors: Kageyama Hiroto , Yamaguchi Nobuyuki
Published: February 2020

The introduction of a large amount of photovoltaic power generation reduces the load on the entire system when the low frequency load is interrupted, but the photovoltaic power generation connected to the relevant line is also separated, so that it becomes an independent operation in the partial system, and the supply power is also reduced. There is a possibility of reduction. In conventional UFLS, after observing the frequency, the load is cut off in units of several seconds. The load shedding amount is determined by the load ratio of the entire system at that time. In this study, the UFLS model will be added to the existing IEEJ AGC30. The demand and solar power output in the target area are divided into substations to create data, and the solar power output of each substation is taken into account to grasp a more accurate load. The validity of this model is verified by simulating frequency fluctuation and LFC operation.
Finite term relations for the exponential orthogonal polynomials
Authors: Gustafsson Björn , Putinar Mihai
Published: February 2020

The exponential orthogonal polynomials encode via the theory of hyponormal operators a shade functiongsupported by a bounded planar shape. We prove under natural regularity assumptions that these complex polynomials satisfy a three term relation if and only if the underlying shape is an ellipse carrying uniform black on white. More generally, we show that a finite term relation among these orthogonal polynomials holds if and only if the first row in the associated Hessenberg matrix has finite support. This rigidity phenomenon is in sharp contrast with the theory of classical complex orthogonal polynomials. On function theory side, we offer an effective way based on the Cauchy transforms ofg,z̅g,…,z̅dg, to decide whether a (d+ 2)-term relation among the exponential orthogonal polynomials exists; in that case we indicate how the shade functiongcan be reconstructed from a resulting polynomial of degreedand the Cauchy transform ofg. A discussion of the relevance of the main concepts in Hele-Shaw dynamics completes the article.
Therapie der kaninen Parvovirose – Übersicht und aktuelle Erkenntnisse
Authors: Gerlach Moira , Proksch Anna-Lena , Dörfelt René , Unterer Stefan , Hartmann Katrin
Published: February 2020

Die kanine Parvovirose ist nach wie vor eine weltweit verbreitete und vor allem bei Welpen häufig auftretende Infektionskrankheit. Die Therapie erfolgt
überwiegend symptomatisch und beinhaltet die Behandlung der akuten gastrointestinalen Symptome sowie die Behandlung und Prävention einer möglichen Sepsis
aufgrund bakterieller Translokation. Neben der antibiotischen Behandlung und der essenziellen Flüssigkeitstherapie ist eine ausreichende antiemetische und
analgetische Medikation sinnvoll. Weiterhin sollte eine möglichst frühzeitige enterale Ernährung angestrebt werden, da dies die Genesungszeit verkürzt. Die
gezielte Modulation der intestinalen Mikrobiota kann die klinische Symptomatik reduzieren und möglicherweise langfristige Folgen, wie chronische
Darmerkrankungen, verhindern. Eine antivirale Therapie mit dem rekombinanten felinen Interferon-Omega führte in mehreren Studien zu einer geringeren
Mortalitätsrate und einer schnelleren Besserung der klinischen Symptome.
Intranasale Applikation von Medetomidin bei Hunden
Authors: Betz Daniela Simon
Published: February 2020

Jafarbeglou M, Marjani M. Comparison of the sedative effects of medetomidine administered intranasally, by atomization or drops, and intramuscular injection in
dogs. Vet Anaesth Analg 2019; 46: 815–819

Die intranasale Gabe stellt eine nicht invasive und praktische Form der Medikamentenapplikation dar. Die hochvaskularisierte Mukosa der Nasenhöhle ermöglicht
eine schnelle Absorption und ein direkter Nasen-Hirn-Transport kann unter Umgehung der Blut-Hirn-Schranke über die Nn. olfactorii und trigemini sowie die
Zerebrospinalflüssigkeit effektive Wirkstoffkonzentrationen im Zentralnervensystem bewirken. Ziel dieser Studie war, die sedative Effektivität von
intranasal – per Zerstäuber oder in Tropfenform – appliziertem Medetomidin im Vergleich zur intramuskulären Gabe zu untersuchen.
Therapie von nervenbezogenen muskuloskelettalen Schmerzen
Authors: Ridehalgh Colette
Published: February 2020

Neurodynamische Behandlung? Welche Wirkung haben physiotherapeutische Techniken? Auf welchen Mechanismen beruhen sie? Der Artikel gibt Antworten auf diese Fragen
anhand der aktuellen Evidenzlage. Klar ist: Es liegt viel Potential in der Neurodynamik.
USP8 Mutations and Cell Cycle Regulation in Corticotroph Adenomas
Authors: Martins Clarissa Silva , Camargo Renata Costa , Coeli-Lacchini Fernanda Borchers , Saggioro Fabiano Pinto , Moreira Ayrton Custodio , de Castro Margaret
Published: February 2020

Corticotroph adenomas frequently harbor somatic USP8 mutations. These
adenomas also commonly exhibit underexpression of P27, a cell cycle
regulator. The present study aimed to determine the influence of USP8
mutations on clinical features of Cushingʼs disease and to elucidate the
relationship between USP8 mutations and P27 underexpression in these
tumors. Retrospective study with 32 patients with Cushingʼs disease was
followed at the Ribeirao Preto Medical School University Hospital. We
evaluated the patientsʼ clinical data, the USP8 mutation status and
the gene expression of cell cycle regulators P27/CDKN1B,
CCNE1, CCND1, CDK2, CDK4, and CDK6 in
tumor tissue in addition to the protein expression of
P27/CDKN1B. We observed somatic mutations in the exon 14
of USP8 in 31.3% of the patients. Larger tumor size was
observed in patients harboring USP8 mutations (p=0.04), with
similar rates of remission, age of presentation, salivary cortisol at 23:00
h and after 1 mg dexamethasone, ACTH levels, and early postoperative plasma
cortisol. We observed no differences regarding the gene or protein
expression of the cell cycle regulators according to USP8 mutation
status. In this Brazilian series, the observed frequency of USP8
somatic mutations was similar to that reported in European ancestry
populations. Although it was reasonable that USP8 mutations could
contribute to cell cycle dysregulation and P27 underexpression in
corticotroph adenomas, our data did not confirm this hypothesis. It is
possible that increased deubiquitinase activity observed in mutated
USP8 might influence other pathways related to cell growth and
proliferation.
GC-MS Metabolite Profile and Identification of Unusual Homologous Cannabinoids in High Potency Cannabis sativa
Authors: Basas-Jaumandreu Josep , de las Heras F. Xavier C.
Published: February 2020

Phytochemical investigation of the lipids extracted from seeds of Cannabis sativa by GC-MS showed 43 cannabinoids, 16 of which are new. The extract is dominated by Δ9-tetrahydrocannabinolic acid (A) and its neutral derivative trans-Δ9-tetrahydrocannabinol-C5 (THC) Cis and trans-Δ9-tetrahydrocannabinol-C7 isomers with an ethyl-pentyl branched chain together with minor amounts of trans-Δ9-tetrahydrocannabinol with a methyl-pentyl C6 branched side chain were identified as new natural compounds. Four cannabichromene isomers with a C5 side chain are postulated to be derived from the double bond migration at the terminal isoprenyl unit. C7 cannabichromene together with the neutral and acidic forms of cannabinol-C7 were also detected. The mass spectrum of these homologues as trimethylsilyl (TMS) derivatives are presented, and the fragmentation patterns are discussed.
NEUE GESETZE : Die Baustellen von Jens Spahn
Authors: Ehrhardt-Joswig Jana
Published: February 2020

Hieß es vor einem Jahr noch „Erst mal abwarten, ob den vielen Worten tatsächlich Taten folgen“, kann niemand mehr dem Bundesgesundheitsminister absprechen, über einen ausgeprägten Tatendrang zu verfügen. kma hat die wichtigsten Gesetzesänderungen zusammengefasst.
Enhanced magnetocaloric effect via halide substitution in the tunable molecular magnet, Cu9Br2(cpa)6
Authors: Skinner Samuel F. , ter Haar Leonard W.
Published: February 2020

The magnetothermodynamic properties of the low-dimensional 2-D metal organic framework (MOF) halide series, Cu9X2(cpa)6 (X = F, Cl, Br; cpa = anion of 2-carboxypentonic acid), abbreviated as CPA(X), has been the subject of experimental studies suggesting the tunability of magnetic properties via halide and guest-host chemistry. CPA(X) is best described as a topologically spin frustrated triangles-in-triangles or triangulated-Kagome-lattice (TKL) on a layered MOF. CPA(X) consists of microporous channels (oriented transverse to the layers) available for chemical manipulation, which support tunability of properties and the further expansion of this class of materials. While the spin frustrated topology of CPA(Cl) has been shown to exhibit a magnetocaloric effect (MCE) at temperatures less than 10 K, we report here new temperature- and field-dependent magnetization data for CPA(Br). In this study, we estimate the effect of halide interchangeability on the MCE produced by this system in low field and at cryogenic temperatures. Magnetic entropy change (ΔS), relative cooling power (RCP), and refrigerant capacity (RC) are calculated for this material and the effects of halide interchangeability on the MCE are discussed. The CPA(X) series, as a tunable molecular magnet, may also serve as a candidate for quantum spin liquid (QSL) studies and invites chemical manipulation of its magnetic properties, including the MCE.
Microcontroller-based magnetometer using a single nitrogen-vacancy defect in a nanodiamond
Authors: C. Sánchez E. D. , Pessoa A. R. , Amaral A. M. , de S. Menezes L.
Published: February 2020

The measurement of magnetic properties of various physical systems with nanometric spatial resolution raises interest in areas such as materials science, biotechnology, and information storage and processing. In the present work, a microcontroller-based magnetometer was built using a single nitrogen-vacancy defect in a nanodiamond. The implemented nanomagnetometry method is simple and relies on the frequency modulation of the nitrogen-vacancy defect electron spin resonance using square pulses of an externally applied magnetic field and employs a single microwave source. The developed system has a reasonable sensitivity of 4 μT/Hz and is able to measure magnetic field variations at a rate of around 4 mT/s. This system was used for nanoimaging the inhomogeneous spatial magnetic field profile of a magnetized steel microwire, and a spatial magnetic field gradient of 13 μT/63 nm was measured. Besides its usefulness in nanoscale imaging of magnetic fields, the present work can be of interest in the development of compact nanodiamond based magnetometers.
Translation and Affect
Authors: Koskinen Kaisa
Published: February 2020

In an age of AI and automated translation, the affective remains a decisively human condition. Translation and Affect is a collection of essays that investigate the role of affects and emotions across the spectrum of translatorial activities and areas, from public service interpreting to multilingual poetry recitals, from translator training to translation technology. In an effort at creating a consilient approach that bridges different research traditions in Translation Studies, Koskinen uses affective labour and affects and their stickiness as a lens to understand how it feels to translate and how translations feel. Written in a personal and engaging style, the book encourages readers interested in translation issues to look at translation as an affective practice and to explore and reflect their own ways of living with translation.
Quantifying subjective data using online Q-methodology software
Authors: Lutfallah Susan , Buchanan Lori
Published: February 2020

The Q-Sort methodology has been used to study participants’ subjective views on various topics (Brown, 1996). The task has historically been completed by manually sorting cards into
categories that force responses into a normal distribution (Brown, 1996). Data
collection using this method is time consuming and manual data entry is prone to human error. We describe here QMethod Software –
a computerized web-based application that allows participants to sort and record their responses online. This online application
eliminates the need for researchers to attend the study sessions and to manually enter data. QMethod Software described here is
currently being used in both applied and cognitive psychology studies, including a clinical study that evaluates participants’
perception of behaviours seen as most characteristic or most uncharacteristic of psychological aggression or coercive control in
situations of intimate partner violence. In a health psychology study, it is being used to examine people’s perceptions of food
allergy, and in a psycholinguistics lab it was used to evaluate the affective valence, abstractness, and semantic richness ratings
of words. We will show here that the data obtained from one of these psycholinguistic studies (abstractness/concreteness)
correlates highly with existing measures (Brysbaert, Warriner & Kuperman, 2014)
thus demonstrating that the Q-sort methodology and this particular implementation, the QMethod Software app, reproduces more
typical evaluations/assessments in the psycholinguistics literature.
Global policies for moving cities: the role of think tanks in the proliferation of Bus Rapid Transit systems in Latin America and worldwide
Authors: Silva Ardila Diego
Published: February 2020

Implementation in the late nineties of Transmilenio, a Bus Rapid Transit (BRT) based transportation policy in Bogotá (Colombia), marked an inflection milestone for the replication processes of such urban transportation policies. Multiple actors and actions brought the Transmilenio model to numerous cities worldwide, first replicated in other Colombian and Latin American cities later it reached Turkey, China and India and then spread all over the world. This article explores the role of think tanks steering and promoting BRT policies during complexes processes and interactions of power among multiple scales. In doing so, the article situates itself within the research arenas studying linkages between local interests, demands and needs and the global neoliberal allocation of capital and expertise via consulting, advising commerce and construction activities. I argue that BRT promotion think tanks have emerged as powerful mechanisms mobilizing specific transportation policies acting as facilitators of movements via ‘policy translators’, promoters and network developers among the plethora of actors and interests. Methodology utilized is based on data from policy reports, archives and in-depth interviews exploring networked interactions while tracing linkages between think tanks and policy actors and observing knowledge dissemination arenas. This research contributes to the exploration of urban transportation epistemic communities and its role in urban change under a neoliberal global context and underlines the role of emerging policies from the south that permeate global policy arenas, traditionally dominated by actors from developed economies and discusses the mediation of global north institutions in the global south urban policy mobilities landscape.
Electronic structure and spatial inhomogeneity of iron-based superconductor FeS*
Authors: Wang Chengwei , Wang Meixiao , Jiang Juan , Yang Haifeng , Yang Lexian , Shi Wujun , Lai Xiaofang , Mo Sung-Kwan , Barinov Alexei , Yan Binghai , Liu Zhi , Huang Fuqiang , Jia Jinfeng , Liu Zhongkai , Chen Yulin
Published: February 2020

Iron-based superconductor family FeX (X = S, Se, Te) has been one of the research foci in physics and material science due to their record-breaking superconducting temperature (FeSe film) and rich physical phenomena. Recently, FeS, the least studied FeX compound (due to the difficulty in synthesizing high quality macroscopic crystals) attracted much attention because of its puzzling superconducting pairing symmetry. In this work, combining scanning tunneling microscopy and angle resolved photoemission spectroscopy (ARPES) with sub-micron spatial resolution, we investigate the intrinsic electronic structures of superconducting FeS from individual single crystalline domains. Unlike FeTe or FeSe, FeS remains identical tetragonal structure from room temperature down to 5 K, and the band structures observed can be well reproduced by our ab-initio calculations. Remarkably, mixed with the 1 × 1 tetragonal metallic phase, we also observe the coexistence of

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reconstructed insulating phase in the crystal, which not only helps explain the unusual properties of FeS, but also demonstrates the importance of using spatially resolved experimental tools in the study of this compound.
Ethnomedicine, phytochemical, and toxicity activity of several alleged medicinal plants from Sebangau National Park, Central Borneo
Authors: Pasaribu G , Waluyo TK
Published: February 2020

Indonesia is a country endowed with its abundant biodiversity; and therefore potential in providing future drugs derived from renewable natural materials (e.g. plants). Relevantly, this study aimed to identify and analyze the ethnomedicine, phytochemical, toxicity, and active compounds of several alleged medicinal plant species from Borneo. Results showed local people used those plants to cure various diseases or other human physiological disorders, such as antidote, varices, liver medicine, tonsil medicine, stomachache, diarrhea, sprue medicine, itching, ulcers antihypertension and malaria. Those plants as examined generally contained tannins, saponins, flavonoids, and triterpenoids. Some of them contained alkaloids. Toxicity tests, as represented by LC50 values, exhibited their range from 126.70 to 883.34 ppm. Further, various chemical compounds such as trans-caryophyllene and veridiflorol effectively inflicted a significant effect as antimicrobial, antifungal, and antibiotics. Fatty acids such as hexadecanoic acid, palmitic acid, linoleic acid, octadecadienoic acid, and stearic acid could inhibit the growth of microbes. Phenolic compounds could acts as an antioxidant and antidiabetic. Judging from all the varying LC50 values, ethnobotany-related explorations, and other biomedical/biochemical tests, those analyzed species could be strongly judged as efficacious medicinal plants; and therefore potentially developed as raw material for herbal drugs.
Adaptation and productivity of kaliandra for biomass energy source
Authors: Siarudin M , Indrajaya Y
Published: February 2020

The development of wood energy forest plantations is one of the government’s strategies to meet national energy needs. Kaliandra (Calliandra calothyrsus) is one tree/shrub species that is potential for biomass energy source due to its rapid growth and high calorific value. This study aims to analyze the level of adaptation and productivity of kaliandra planted in 3 spacing treatments in the Production Forest Management Unit (KPHP) Puncak Ngengas - Batulanteh, Sumbawa. The treatment of spacing applied is 4 m x 1 m or density of 2, 500 trees/ha (J1), 4 m x 2 m or density of 1, 250 trees/ha (J2), and 4 m x 2 m with stripe or density of 1, 850 trees/ha (J3). Measurements of adaptation and plant growth were carried out until 6 months after planting. The results of this study indicate that the J2 treatment showed the best level of adaptation with a survival rate of 89.3%, followed by treatments J3 and J1 with a survival rate of 85.9% and 84.4% respectively. The J3 treatment resulted in the best growth rate of Kaliandra plants with an average diameter of 18.1 mm, an average height of 244.9 cm and the volume of individual trees of 0.00085 m3/tree. The J3 treatment also produced the highest total volume, estimated biomass production and energy productivity compared to other treatments, which were 3.5 m3/ha, 2.7 tons/ha and 51.9 Gj/ha, respectively. Treatment of spacing indicates the influence on the level of tree adaptation and growth and estimation of biomass production and calorific value. However, the treatment of spacing does not show a clear pattern related to the effect of initial spacing on growth and productivity of Kaliandra at the beginning of the year.