bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Use of a Learning-Based Exergame to Enhance Physical Literacy, Soft Skills, and Academic Learning in School-Age Children: Pilot Interventional Study (Preprint)
Authors: Goncalves Aurelie , Lespiau Florence , Briet Gaëtan , Vaillant-Coindard Eugénie , Palermo Angèle , Decobert Elsa , Allegret-Bourdon Nathan , Charbonnier Elodie
Published: October 2023

BACKGROUND

There is ample evidence that most children do not perform enough physical activity (PA). To address this major public health problem, the French government implemented 30 minutes of daily PA (DPA) at schools but did not provide any supplemental resources or concrete guidance. Considering both children’s interest in video games and the need for teachers to complete their curriculum, the use of a learning-based exergame that combines PA and learning appears particularly relevant.

OBJECTIVE

The first objective of this study was to evaluate the feasibility of implementing 30 minutes of DPA through exergaming among school-age children. The second objective was to examine the effects of an exergaming program on physical literacy, academic learning, and soft skills (motivation, self-efficacy, and concentration).

METHODS

This interventional study had a pre-post design and used the Play LÜ exergame platform. The study included 79 children with a mean age of 8.9 (SD 1.2) years from grade 2 (7 years old) to grade 5 (11 years old). Play LÜ requires players to throw balls against a wall to reach a target or to activate an object and provides an interactive game area for educational activities linked to specific learning themes. After a 4-session familiarization phase during which the teachers chose to prioritize mathematics learning in 30-minute DPA sessions, students took part in DPA sessions over a period of 3 weeks with Play LÜ and a motor skills circuit behind the LÜ setup to keep them continuously active. All sessions were carried out by PA specialists. Each session started with a warm-up using the Grööve application, continued with main activities promoting mathematics learning adapted to each grade level, and ended with a 3-minute meditation for returning to a calm and serene state using the Gaïa application. Before (T0) and after (T1) the program, students completed a self-evaluation booklet to assess their levels of physical literacy, academic performance, and soft skills.

RESULTS

The implementation of this exergaming program was welcomed by the school’s administration, teaching staff, and parents. After the program, we observed increased scores for physical literacy (difference +2.6, percentage change +3.6%; W=933.0; P=.002; rrb=−0.39, 95% CI −0.58 to −0.16) and motivation in mathematics (+0.7, +9.8%; W=381.5; P=.005; rrb=−0.44, 95% CI −0.66 to −0.16). In addition, it is important to note that some measures progressed differently across learning levels and age groups.

CONCLUSIONS

The study results indicate positive impacts of learning-based exergaming on physical literacy and motivation in mathematics among school-age children.
Pressure Ulcer Management Virtual Reality Simulation (PU-VRSim) for Novice Nurses: Mixed Methods Study (Preprint)
Authors: Jung Soo Youn , Moon Kyoung Ja
Published: October 2023

BACKGROUND

Pressure ulcers (PUs) are a common and serious complication in patients who are immobile in health care settings. Nurses play a fundamental role in the prevention of PUs; however, novice nurses lack experience in clinical situations. Virtual reality (VR) is highly conducive to clinical- and procedure-focused training because it facilitates simulations.

OBJECTIVE

We aimed to explore the feasibility of a novel PU management VR simulation (PU-VRSim) program using a head-mounted display for novice nurses and to investigate how different types of learning materials (ie, VR or a video-based lecture) impact learning outcomes and experiences.

METHODS

PU-VRSim was created in the Unity 3D platform. This mixed methods pilot quasi-experimental study included 35 novice nurses categorized into the experimental (n=18) and control (n=17) groups. The PU-VRSim program was applied using VR in the experimental group, whereas the control group received a video-based lecture. The PU knowledge test, critical thinking disposition measurement tool, and Korean version of the General Self-Efficacy Scale were assessed before and after the intervention in both groups. After the intervention, the experimental group was further assessed using the Clinical Judgment Rubric and interviewed to evaluate their experience with PU-VRSim.

RESULTS

The results compared before and after the intervention showed significant improvements in PU knowledge in both the experimental group (P=.001) and control group (P=.005). There were no significant differences in self-efficacy and critical thinking in either group. The experimental group scored a mean of 3.23 (SD 0.44) points (accomplished) on clinical judgment, assessed using a 4-point scale. The experimental group interviews revealed that the VR simulation was realistic and helpful for learning about PU management.

CONCLUSIONS

The results revealed that PU-VRSim could improve novice nurses’ learning of PU management in realistic environments. Further studies using VR for clinical training are recommended for novice nurses.
Precariedad laboral y desigualdad salarial entre profesores universitarios
Authors: Solares Israel G. , Vera Héctor
Published: October 2023

Este artículo analiza las desigualdades laborales y de ingresos salariales entre los profesores de tiempo completo y de asignatura en la Universidad Nacional Autónoma de México (UNAM). Se presenta una estimación de los ingresos de más de 30 mil profesores por hora, tiempo completo y académicos-funcionarios. Para poner en perspectiva el grado de desigualdad imperante en la UNAM se realizan tres comparaciones: 1) los salarios de los profesores de asignatura con los de tiempo completo en la UNAM; 2) los salarios de los profesores de asignatura de la UNAM con sus similares en otras universidades mexicanas; 3) el nivel de desigualdad de la UNAM con el de otras universidades. Además, se sugieren mecanismos para explicar cómo se reproduce la desigualdad entre distintos tipos de académicos y cómo se perpetúa el acaparamiento de oportunidades y recursos que benefician a los profesores de tiempo completo a costa de los profesores por hora.
NUMERICAL SIMULATION OF THE STRESS-STRAIN STATE OF A LARGE-SPAN STRUCTURE WITH JOINTS WITH GAP UNDER THE SEISMIC LOADS IN A TRANSIENT DYNAMIC
Authors: Belostotsky Alexander , Pavlov Andrei , Nagibovich Alexandr
Published: October 2023

The article presents the results of numerical simulation of a unique long-span structure subjected to seismic loads. The roof and facade of structures were connected to reinforced concrete base with joints with gaps. The simulation was realized for ideal model and model with gap imperfections. Various modeling approaches for the joints and the resulting dynamic response were examined.
(Not)real value: The impact of the reliability of financial statements on the value of the company
Authors: Nemtseva Yulia V. , Valeeva Anastasia S.
Published: October 2023

The article presents methodological tools for assessing the value of the company, taking into account the fact of distortion of the accounting (financial) statements of the company. The reliability of the reporting of companies of the type of economic activity “Construction” is determined - one of the most important industries for the development of the Siberian Federal District (SFD) in the post-pandemic reality. The cost of construction companies of the SFD is estimated, the existence of a relationship between the manipulation of reporting and the value of the company is revealed. The authors propose an algorithm for assessing the value of the company, taking into account the fact of manipulation of reporting data. The steps of the algorithm of actions involve building a probit regression on an array of reporting data of companies with an interesting type of economic activity, determining the probability of manipulating reporting data based on the regression obtained, assessing the real value of the company taking into account the facts of manipulation. The proposed methodology for assessing the value of a company, taking into account manipulation, can be used to make management and investment decisions by external and internal stakeholders, including banks, credit organizations, suppliers, owners of construction companies, and other interested parties.
UPAYA MENINGKATKAN KETERAMPILAN 4C (CRITICAL THINKING, COLLABORATIVE, COMMUNICATIVE, DAN CREATIVE) MELALUI PROJECT BASED LEARNING
Authors: Putri Neuwidia Nuzul , Ningsih Kurnia , Supartini Sri
Published: October 2023

Softskills in the form of 4C skills (critical thinking, creativity, communication, and collaborative) need to be equipped to students through strategies that can be used by educational institutions. The purpose of this study was to improve students' 4C skills by applying the Project Based Learning (PjBL) model. This type of research is Classroom Action Research (PTK). The classroom action research procedure was carried out with two cycles with two meetings in each cycle. This study used instruments in the form of observation sheets and written evaluation tests. Data collection techniques in this study include (1) observation, (2) tests, and (3) documentation. The results showed an increase in 4C skills through Project Based Learning (PjBL). Critical thinking skills at the end of cycle II increased by about 46.7% from 33.3% to 80%. Collaborative skills at the end of cycle II increased by about 20% from 66.7% to 86.7%. Communication skills at the end of cycle II increased by about 26.7% from 53.3% to 80%. Creative thinking skills at the end of cycle II increased by 40% from 46.7% to 86.7%. It is concluded that this research proves that 4C skills (critical thinking, collaborative, communicative, and creative) can be improved effectively by applying the Project Based Learning (PjBL) model.
COPD in Non-Smokers in South Asia: An Under Estimated and Unrecognized Condition
Authors:   Bilawal Medical College, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh-Pakistan, Piryani Rano Mal , Piryani Suneel ,   Public Health Professional, Karachi, Sindh-Pakistan.
Published: October 2023

COPD is an acronym used for chronic obstructive pulmonary disease. Globally, it is one of the leading causes of morbidity and mortality. It is among the significant causes of death in the developing countries of the world too. A major established causal risk factor for COPD is tobacco smoking.
Urban Wild_Life: Exploring affective relationships with wild urban nature through creative digital practices
Authors: Joanne Scott
Published: October 2023

This research project arose from encounters with wild more than human beings in city spaces close to where I live. The encounters themselves were very rich, complex and flowing over with meanings and feelings that I couldn’t quite grasp in the moment of their happening. As a practitioner-researcher, I therefore chose to explore these feelings and meanings through creative practice, while also engaging in academic research to position these encounters in discourses, both directly relevant and those that resonate with the ideas and feelings arising. I characterise this as a project that aligns with and is productively informed by multispecies studies and practices. In its mixing of encounters with wild nature through primarily digital images and sounds, the practice activates an ‘ecology of technology’
Cardenolides in the defensive fluid of adult large milkweed bugs have differential potency on vertebrate and invertebrate predator Na+/K+¬–ATPases
Authors: Rubiano-Buitrago Paola , Pradhan Shrikant , Aceves-Aparicio Alfonso , Mohammadi Shabnam , Paetz Christian , Rowland Hannah
Published: October 2023

The defences of aposematic animals are characterised by diversity and
variability of secondary metabolites. Here we examine the nature and
function of chemical defence diversity in large milkweed bugs,
Oncopeltus fasciatus, testing the hypothesis that different chemical
defence compounds have evolved in response to different enemies. We
profiled and quantified the cardenolides sequestered by large milkweed
bugs in their defensive secretions and their bodies, and measured the
inhibitory properties of a subset of isolated milkweed cardenolides in
the insect’s defence against the Na+/K+—ATPase target site of
vertebrate and invertebrate predators, using porcine Na+/K+—ATPase
data as a reference. We show that highly concentrated coroglaucigenin
cardenolides in the insect’s defence (glucopyranosyl frugoside and
frugoside) are toxic for both resistant and sensitive predators, whereas
corotoxigenin and calotropagenin cardenolides have varying degrees of
enzyme inhibition among various predators. Overall, O. fasciatus is well
defended against a range of enemies due to the differential effect of
these compounds´ target sites. Our results suggest that the compounds
the insect sequester have evolved in response to predation pressure.
Agave distribution and floral display influence foraging rates of an endangered pollinating bat and implications for conservation
Authors: Lear Kristen , Moore Clinton T. , King Elizabeth G. , Ruiz Emma P. Gómez , Maldonado Jose Juan Flores , Sanchez Cuauhtemoc Ibarra , Aguilera Ana Castañeda , Prebyl Thomas , Hepinstall-Cymerman Jeff
Published: October 2023

Wildlife conservation involves making management decisions with
incomplete knowledge of biological and ecological relationships. Efforts
to augment foraging resources for the endangered Mexican long-nosed bat
(Leptonycteris nivalis) are progressing despite limited knowledge about
the species’ foraging behavior and requirements. This study sought to
fill knowledge gaps about L. nivalis responses to floral resource
availability by addressing individual plant and local-scale (30 m)
characteristics that influence visitation rates to flowering agaves. We
observed bat visitation at 62 flowering agaves around two roosting caves
in northeast Mexico on 46 nights in summers 2017 and 2018. We found
visitation rate had positive relationships with two agave-scale
characteristics: the number of umbels (flower clusters) with open
flowers and earlier phenological stages of plants. A negative
interaction between the significant predictors indicated that direction
of the relationship between visitation and either characteristic
depended on the level of the other characteristic. We also found
relationships between visitation rate and two local-scale
characteristics: negative for the density of flowering conspecifics
within 30 m of the focal plant and positive for the density of dead
standing stalks within 30 m. Our findings suggest opportunities to
augment foraging resources for L. nivalis in ways that are consistent
with the bats’ foraging behavior, including: planting larger agave
species with more flowers, planting multiple species of agaves with
different flowering times to ensure nectar availability when L. nivalis
is present in northeast Mexico, planting agaves in clusters, and keeping
dead standing stalks on the landscape. Our study highlights important
considerations for management actions, which will ultimately aid the
development of ongoing conservation efforts.
Hot wire thermopol cutting using CNC machine
Authors: Memon Shahzor , Kalwar Imtiaz Hussain , Memon Abdul Hameed , Shakir Muhammad , Mustafa Halar , Rehman Sadiq ur
Published: October 2023

Recently, the Hot Wire CNC Technology is use for the purpose of cutting of the materials like thermopol and foam for the packaging of products. This technology saves labor costs and increases production. The main objective of the research is to determine the influence of wire temperature on the quality of cuts achieved through hot wire cutting technology and explore the optimal material combination for low power consumption in wire cutting technology. The technique utilizes controlling the current regulation of the Nichrome wire, to reduce the power consumption. The Hot Wire CNC Machine is controlled by a micro controller which sends a special code called G-Code to the stepper motors and the current regulation is controlled by PWM (Pulse Width Modulation) through Power transistor. The results of the study show a sufficient reduction in power consumption when using the combination of Nickel-chromium materials.
Site suitability for intercity bus terminal at Hyderabad, Pakistan: a citizen’s perception
Authors: Memon Sania Rehman , Talpur Mir Aftab Hussain , Arain Furqan Javed
Published: October 2023

The city of Hyderabad, Pakistan has been facing a shortage of bus terminals over the years. The native transportation arrangement already increased traffic jams in the city. Besides, passenger buses that arrived in Hyderabad from other suburban cities had caused chaos and increased traffic management issues. Constructing a new bus terminal for the city in an accessible location is determined in this study. To examine the demand for a bus terminal and to determine a proper location, the data were collected from the 480 sampled respondents with the help of a questionnaire survey. Experts from the Hyderabad Development Authorities were consulted on the availability of land for the proposed development of the terminal. To generate suitable information, descriptive statistics and the correlation approach were employed. GIS-based maps were also produced to define the land uses and routes of the city. This research recommends four standard sites for the terminal, i.e., the Mayani Main Forest (Ayub Hotel), Toll Plaza, Kohsar (Gulshan-e-Sarmast), and Zeal Park. Based on expert opinion, the Ayoub Hotel site was found more suitable for constructing a new bus terminal. In this way, this study contributed to the development of a new bus terminal for the city, which has been the demand of the citizens for quite some time.
Pengaruh Instrumen Penilaian Kognitif Berbasis Hots (Higher Order Thinking Skill) Terhadap Keterampilan Pemecahan Masalah Peserta Didik Pada Mata Pelajaran Ppkn Di Sma Negeri 1 Pagelaran Tahun Pelajaran 2020/2021
Authors:   Universitas Lampung, Karerina Nina
Published: October 2023

Tujuan penelitian ini untuk mengetahui pengaruh instrumen penilaian kognitif berbasis HOTS terhadap keterampilan pemecahan masalah peserta didik pada mata pelajaran PPKn di SMA Negeri 1 Pagelaran tahun pelajaran 2020/2021. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan pendekatan kuantitatif. Subjek dalam penelitian ini adalah peserta didik kelas XI di SMA Negeri 1 Pagelaran. Sampel dalam penelitian ini berjumlah 44 responden. Teknik pengumpulan data menggunakan teknik utama yaitu angket dan teknik penunjang yaitu wawancara dan dokumentasi. Alat bantu untuk menganlisis data pada penelitian ini yaitu menggunakan SPSS versi 23. Hasil penelitian menunjukkan bahwa terdapat pengaruh instrumen penilaian kognitif berbasis HOTS terhadap keterampilan pemecahan masalah peserta didik pada mata pelajaran PPKn di SMA Negeri 1 Pagelaran tahun pelajaran 2020/2021 dengan besar persentase pengaruhnya yaitu 63,1% dengan indikator variabel independen (X) yaitu: mengukur kemampuan berpikir tingkat tinggi, berbasis permasalahan kontekstual, dan tidak rutin dan mengusung kebaruan sedangkan untuk variabel dependen (Y) yaitu: memahami masalah, merencanakan penyelesaian, menyelesaikan masalah sesuai dengan rencana, dan melakukan pengecekan terhadap semua langkah yang telah dilaksanakan. Dengan demikian dapat disimpulkan bahwa instrumen penilaian kognitif berbasis HOTS berpengaruh 63,1% terhadap keterampilan pemecahan masalah peserta didik pada mata pelajaran PPKn di SMA Negeri 1 Pagelaran tahun pelajaran 2020/2021
Keputusan Pembelian Berbelanja di E-Commerce pada Masyarakat Kelas Bawah di Jakarta
Authors:   Universitas Negeri Jakarta, Ridho Mutia Aisyatur , Lestariningsih Dwi Sukanti , Hardi Ode Sofyan
Published: October 2023

Penelitian ini bertujuan untuk mengetahui keputusan Pembelian Berbelanja di e-commerce pada masyarakat kelas bawah di Jakarta yang tercermin dalam aspek ruang, waktu, internal dan eksternal. Penelitian ini menggunakan metode deskriptif dengan pendekatan survei. Dasar penggolongan kelas sosial bawah dilihat dari Index Of Social Position (ISP) yang diambil di RW Kumuh. Populasi dalam penelitian ini adalah masyarakat kelas sosial bawah di RW 08 Kel. Pejaten Barat. Sampel diambil sebanyak 30 responden. Hasil penelitian menunjukkan bahwa pada aspek ruang, Masyarakat kelas bawah lebih sering membeli produk fashion di toko online dengan e-commerce. Dimana yang paling banyak dibeli di Jabodetabek adalah fashion. Hal ini karena harga lebih murah ketika membelinya di toko online dan terdapat banyak promo dan yang paling banyak dibeli di luar Jabodetabek adalah produk fashion. Pada aspek waktu, rata-rata melakukan belanja di toko online sebanyak kurang dari 3 kali dalam sebulan. Pada aspek internal, Tujuan memilih berbelanja di e-commerce adalah karena harga lebih murah. Tempat belanja e-commerce yang sering dikunjungi adalah Lazada dan shopee dan metode pembayaran yang sering digunakan adalah COD atau bayar di tempat. rata – rata biaya pengeluaran belanja di e- commerce dalam sebulan sebesar Rp. 100.000 – 500.000. Pada aspek eksternal, bentuk promosi yang bisa mempengaruhi berbelanja di e-commerce yang paling tertarik adalah iklan.
Pengaruh Pabrik Gula PTPN VII Terhadap Ekonomi dan Kesejahteraan Petani Binaan Desa Sukamaju Kecamatan Bunga Mayang Kabupaten Lampung Utara Pada Tahun 2013-2018
Authors:   Universitas Lampung, Usniatuti Rini , Imron Ali , Ekwandari Yustika Sri
Published: October 2023

Pengaruh Pabrik Gula Ptpn Vii Terhadap Ekonomi Dan Kesejahteraan Petani Binaan Desa Sukamaju Kecamatan Bunga Mayang Kabupaten Lampung Utara Pada Tahun 2013-2018. Tujuan penelitian untuk mengetahui Pengaruh Pabrik Gula PTPN VII terhadap ekonomi dan kesejahteraan petani binaan di Desa Sukamaju Kecamatan Bunga Mayang pada tahun 2013- 2018. Menggunakan metode deskriptif dengan teknik pengumpulan data wawancara, dan dokumentasi. Teknik analisis data yang digunakan yaitu reduksi data, dan penyajian data. Hasil analisis dan pembahasan menunjukkan bahwa daya dukung secara langsung membuka lapangan kerja dalam peningkatan ekonomi petani, terlihat dari tingkat pendidikan, kesehatan, perumahan, dan fasilitas hidup berkembang, daya hambat secara langsung tingkat efisiensi pabrik gula berhenti kerja mesin giling mempengaruhi hasil produksi gula. Daya dukung secara tidak langsung pemberian modal pinjaman Bank yang digandeng oleh pabrik gula, serta daya hambat secara tidak langsung rendahnya rendemen yang dihasilkan belum bisa mencapai patokan dari Asoisiasi Gula Indonesia sebesar 9,00%.
Pengaruh Kebijakan Adaptasi Kebiasaan Baru 3M Terhadap Tingkat Kepatuhan Masyarakat
Authors:   Universitas Lampung, Adha Muhammad Mona , Nurmalisa Yunisca , Pitoewas Berchah
Published: October 2023

Pandemi Covid-19 saat ini masih berlangsung, baik secara global maupun secara nasional. Sampai saat ini, belum ada tanda-tanda pandemi ini akan berakhir walupun secara global dan nasional program vaksinasi sudah berjalan tetapi hal tersebut belum menjadi jaminan sepenuhnya terhindar dari bahaya Covid-19. Sementara itu, untuk meminimalisir bahaya Covid-19 yang bisa saja semakin besar, pemerintah Indonesia sendiri mengeluarkan kebijakan. Pemerintah, terhitung sudah mengeluarkan beberapa kebijakan semenjak Covid-19 masuk ke Indonesia seperti kebijakan pembatasan sosial berskala besar (PSBB), kebijakan adaptasi kebiasaan baru(AKB), dan kebijakan pembatasan kegiatan masyarakat berskala mikro (PPKM). Kebijakan adaptasi kebiasaan baru, merupakan salah satu kebijakan yang membuat kita agar tetap bisa beraktifitas di tengah kondisi Covid-19 dengan tetap memperhatikan protokol kesehatan yang berlaku. Artikel ini bertujuan untuk menganalisis dan melihat bagaimana pengaruh kebijakan adaptasi kebiasaan baru 3m terhadap tingkat kepatuhan masyarakat. Metode yang digunakan dalam karya penulisan ini menggunakan pendekatan kuanitatif. Hasil dari artikel ini membahas mengenai presentase hasil dari kuisioner yang disebarluaskan kepada responden berkaitan dengan pengaruh kebijakan adaptasi kebiasaan baru 3m terhadap tingkat kepatuhan masyarakat.
Runtuhnya Kejayaan Kopi Priangan Tahun 1870-1900
Authors:   Universitas Lampung, amarina khoirunnisa , Susanto Henry , Sumargono Sumargono
Published: October 2023

Tahun 1870-1900 adalah tahun dimana pemerintah Belanda memberikan peluang kepada pengusaha swasta untuk menanamkan modalnya di Hindia-Belanda, khususnya pada bidang perkebunan. Tanaman kopi merupakan salah satu jenis tanaman ekspor yang laku di pasar internasional, wilayah Hindia-Belanda yang terkenal sebagai penghasil kopi adalah Priangan. Ketika masa Tanam Paksa tanaman kopi sangat memberikan keuntungan bagi kas negeri Belanda. Namun ketika masa Liberal diterapkan di Hindia-Belanda kopi Priangan mengalami penurunan ekspor ke pasar internasional. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang menyebabkan runtuhnya kejayaan kopi Priangan pada tahun 1870-1900. Metodologi dalam penelitian ini adalah metode historis dengan empat langkah penelitian: Heuristik (mencari serta mengumpulkan arsip melalui ANRI), Kritik (melihat keaslian sumber serta isi dari arsip yang telah ditemukan), Interpretasi (menafsirkan data yang diperoleh), Historiografi (menulis cerita sejarah dalam bentuk skripsi). Teknik analisis data yang digunakan teknik analisis data historis, kegiatan yang diawali pengumpulan data, kritik sumber yang dikaitkan dengan teori serta metode penelitian sejarah dan kemudian menjadi sebuah fakta sejarah. Hasil penelitian ini menunjukkan: runtuhnya kejayaan kopi Priangan tahun 1870-1900 disebabkan oleh beberapa faktor: 1). Meningkatnya pasokan kopi di pasar internasional. 2). Munculnya perkebunan kopi swasta lainnya di wilayah Hindia-Belanda seperti di Jawa Timur, Sulawesi Selatan, Sumatera Utara sehingga munculnya pesaing (kompetitor). 3). Setiap 35 tahun sekali harga kopi turun ke titik terendah dan menurunnya jumlah permintaan kopi dari Brazil sebagai pusat pasar kopi dunia.
Pembelajaran Sejarah Berbasis Internet dan Gawai Di SMA Negeri 3 Martapura Kabupaten Oku Timur
Authors:   Universitas Lampung, Paringja Alhuda Firman
Published: October 2023

Penelitian ini bertujuan untuk mengetahui bagaimana pembelajaran sejarah berbasis internet dan gawai serta faktor pendukung serta penhambat pembelajaran sejarah berbasis internet dan gawai di SMA Negeri 3 Martapura Kabupaten OKU Timur. Penelitian ini menggunakan pendekatan kualitatif dengan pendekatan deskriptif. Pengumpulan data dengan mengambil sebuah peristiwa (deskripsi). Analisis data dilakukan melalui kondensasi data, display data, kategorisasi dan kesimpulan data. Adapun teknik pengumpulan data yang digunakan yaitu observasi, wawancara, dan dokumentasi. Penerapan pembelajaran sejarah yang berbasis internet dan gawai di SMA Negeri 3 Martapura Kabupaten OKU Timur dalam pembelajaran sejarah semua guru sejarah menggunakan model pembelajaran daring secara sinkron, yaitu aplikasi WhatsApp sebagai media pembelajarannya dan pelaksanaan pola pembelajaran sejarah yang berbasis internet dan gawai guru mengacu pada Surat Edaran Nomor 4 Tahun 2020 tentang pelaksanaan kebijakan pendidikan dalam masa darurat penyebaran Coronavirus disease (Covid-19) yaitu Belajar dari Rumah melalui pembelajaran daring/jarak jauh dengan tetap berpedoman pada Permendikbud Nomor 119 tahun 2014. Faktor pendukung pembelajaran sejarah yang berbasis internet dan gawai meliputi; gawai yang memadai, manajemen pendidikan yang baik, SDM (Sumber Daya Manusia) pada guru serta siswa. Faktor penghambat pembelajaran sejarah yang berbasis internet dan gawai meliputi; koneksi internet, gawai yang kurang memadai, kemampuan siswa dalam mengopersikan aplikasi/softwoare, dan kurangnya support belajar dari orang tua.
Pengaruh Kegiatan Karang Taruna Dalam Pengamalan Nilai-Nilai Pancasila Sebagai Etika Berbangsa Dan Bernegara Di Desa Sari Bakti Kecamatan Seputih Banyak
Authors:   Universitas Lampung, Rozak Abdul , Yanzi Hermi , Siswanto Edi
Published: October 2023

Penelitian ini bertujuan untuk mengidentifikasi pengaruh kegiatan karang taruna dalam pengamalan nilai-nilaipancasila sebagai etika berbangsa dan bernegera. Metode yang digunakan dalam penelitian ini adalah menggunakandeskriptif dengan pendekatan kuantitif, serta jumlah yang termasuk dalam populasisebanyak 65 responden anggota karang taruna. Sampel yang digunakan adalah anggota karang taruna yang selanjutnya di interpretasikan sesuai dengan data yang disajikan dari hasil penelitian diketahui nilai signifikansi (Sig.) sebesar 0,000 lebih kecil dari probabilitas 0,05 dan thitung sebesar 6,914lebih besar dari ttabel sebesar 0,2075. Maka H1diterima dan Ho ditolak. Dengan demikiandapat disimpulkan bahwa terdapat pengaruh kegiatan karang taruna dalam pengamalan nilai-nilai pancasila sebagai etika berbangsa dan bernegara di desa Sari Bakti kecamatan Seputih Banyak.
STRATEGY FOR MANAGING REGIONAL COMPETITIVENESS DEVELOPMENT
Authors: Mann Ruslan
Published: October 2023

Abstract. The studies of economists are mostly devoted to the issues of ensuring the proper level of competitiveness of the country and finding ways to increase Ukraine's competitiveness rating in the world ranking. At the same time, there are many unsolved problems related to the competitiveness of the country's regions and the need to develop a strategy for managing regional competitiveness development, which indicates the relevance of the topic of research. The purpose of the article is theoretical substantiation of the essence of regional competitiveness and the development of a strategy of regional competitiveness development. The article examines the essence of the concept of "competitiveness" in relation to various objects: country, region, enterprise, products. The competitive advantages of the region have been studied and determined. The indicators used to assess the level of competitiveness of the region are grouped into blocks. An algorithm for increasing the competitiveness of the region, presented in the form of successivesteps: determination of strategic level of the competitiveness of the region; identification of main consumers and buyers of regional production; determination and increase of strategic factors of competitiveness of the region; formation of a strategy of regional competitiveness development; activation of the quality of regional business environment; formation of competitive regional market, has been developed. The necessity ofstrategic planning of regional competitiveness development is proved, the tasks and main characteristics of strategic planning are clarified. A mechanism of strategic management of regional competitiveness development, which involves the following stages: determination of target indicators of regionaldevelopment; strategic assessment of regional competitiveness; execution of necessary measurements in the region; implementation and adjustment of strategic plan is proposed. A mechanism of tactical planning of regional competitiveness development, which involves the creation of an information base about the region; performance of SWOT analysis of the region; positioning of the region; development of marketing and logistics strategy; implementation of the developed plan and monitoring and control over its implementation, is developed.
PECULIARITIES OF THE DEVELOPMENT OF THE IT SPHERE IN THE CONTEXT OF DIGITAL TRANSFORMATION OF THE ECONOMY OF UKRAINE
Authors: Levchenko Oleksandr , Viunyk Olha
Published: October 2023

Abstract. The article identifies key problems that hold back the prospects for developing the potential of the IT sphere in Ukraine. The specifics of functioning and development of the IT sphere in Ukraine in the conditions of digital transformation of the economy are considered. The paper analyzes the main scientific approaches to defining the essence of the definition "digital economy". Positive and negative aspects of the influence of digital economy and digital tools on the development of the IT sphere, employment of the population, and the course of business processes of economic entities are systematized. A comparative analysis of the values of indices of network readiness of Ukraine with respect to developed countries of Europe and the world is given. The influence of indices of access to information and communication technologies and the use of ICT on the state of development of digital economy of a certain country is determined. The main trends of new technologies within the framework of the formation of Industry 4.0, including: blockchain technologies, artificial intelligence, creation of "digital doubles", use of drones, 3D printing technologies, VR/AR, cyber security tools, etc., have been established. The fact of rapid development of the IT sphere in Ukraine has been established. At the same time, in terms of international comparisons, Ukraine lags behind developed countries of the world in terms of indicators characterizing the trends in the development of digital economy. The dynamics of changes in the number of individual entrepreneurs in the field of IT has been studied. It has been established that the digitalization of theeconomy radically changes the sphere of work and employment, increasing the share of digital workplaces, volumes of remote and virtual employment, as well as changing the structure of employment in general. The directions for improving the development of domestic IT sphere during the acceleration of the processes of digitization of the economy and social life, including the improvement of legislative framework by regulating the activities of business entities in the IT sphere, the development of digital economy, innovative activities and the protection of rights to intellectual property objects, continuous professional development of human resources on mastering and using modern digital technologies, development of social partnership relations and digital culture of citizens, compliance with cyber security and information protection measures, are substantiated.
EXPLORING STUDENTS’ AND LECTURERS’ ANXIETY IN LEARNING ENGLISH DURING EMERGENCY REMOTE TEACHING IN A PUBLIC UNIVERSITY IN NORTH BALI
Authors: Santosa Made Hery , Wulandari Ni Luh Putu Novi , Mahendrayana Gede
Published: October 2023

This study aimed to investigate students' and lecturers’ anxiety in learning English during emergency remote teaching in a public university in North Bali. This study was formed in a quantitative study. The data were collected by doing a survey and giving the questionnaire that was developed based on the FLCAS (Foreign Language Classroom Anxiety Scale) for the participants. There were 200 university students and 9 lecturers of English Language Education in the research setting as the participants. The study found that the university students’ level was mildly anxious or indicated a moderate level of anxiety. Meanwhile, the lecturers’ anxiety level was very relaxed or indicated as low anxiety level. From the results, it can be concluded that most of university students did not feel afraid and happy. Meanwhile, the lecturers felt joy in teaching and learning English during the emergency remote teaching.
EXPLORING I-YOU INDEXICALS IN GHANAIAN CHURCH MUSIC
Authors: Dwamena Daniel Ofosu , Gyimah Manu James , Freitas Philip Kwame
Published: October 2023

Indexicals are important to contextual inference and generally, in semantic interpretation (Hanks, 1999). The present study set out to examine the use of the I-You indexical pronouns in Ghanaian Church Music. It was revealed that the I-Y spheres of the indexicals received relative frequencies of 4.55% and 3.35% in the data. Again, the study showed various referents of the I-You indexicals and their implication in the data based on their contextual and co-textual cues. The study extends knowledge on the subject of indexicality.
Алгебра Клиффорда как универсальный математический инструмент для описания и объединения гравитации и электромагнетизма
Authors: Бабаев Алимжан
Published: October 2023

В этой обзорной статье обобщённая алгебра Клиффорда (в неевклидовом пространстве) представлена как логический и универсальный математический инструмент для описания процессов электромагнетизма и гравитации. В частности, уравнения Эйнштейна (модифицированные, т.е. с 4-х током) и две независимые системы уравнений Максвелла (однородная и неоднородная с нелинейными поправками) объединяются в рамках алгебры Клиффорда. Законы сохранения 4-х тока, электромагнитный 4-х ток и т.д. приобретают явный геометрический смысл – новую трактовку.
Sudaka
Authors: Morales Carlos M.
Published: October 2023

Este artículo presenta una escucha escrita del legado de Ramiro Musotto a través de su primer disco Sudaka, obra donde conecta al pasado con el presente a través de la percusión, las voces y la tecnología. Proponiendo una audición atenta en relación con la perspectiva de Rodolfo Kusch, escuchamos que Ramiro tuvo esa mirada a nivel regional y a través de la música. De ahí surge esta puesta en valor de su trabajo como músico en Brasil y el mundo, principalmente con el berimbau al que expandió en su uso, expresión y sonoridad.
A somatostatin analogue and immunosuppressive therapy in the treatment of complex forms of chyloperitoneum and chylothorax in newborns and infants
Authors: Gurskaya A. S. , Sulavko M. A. , Bayazitov R. R. , Karnuta I. V. , Ekimovskaya E. V. , Nakovkin O. N. , Akhmedova D. M. , Klepikova A. A. , Khagurov R. A. , Petrova N. V. , Skvortsova V. А.
Published: October 2023

Chyloperitoneum and chylothorax are rare conditions with high mortality rates whose optimal treatment strategy remains unclear. The aim of the study was to evaluate the results of chyloperitoneum and chylothorax treatment with a synthetic somatostatin analogue (octreotide) and immunosuppressive therapy with sirolimus. The study was approved by the Independent Ethics Committee and the Scientific Council of the National Medical Research Center for Children’s Health of Ministry of Healthсare of Russia. The patients' parents gave their consent to the use of their children's data, including photographs, for research purposes and in publications. We conducted a retrospective study of nine children diagnosed with congenital chyloperitoneum and chylothorax who had been treated from 2018 to 2022. All the children received either abdominal or pleural drainage, parenteral nutrition, and conservative therapy with drugs. The first line of therapy was octreotide for 14–20 days that was then switched to sirolimus if there had been no effect. The effectiveness of conservative therapy with octreotide at a dose of 5–10 µg/kg/hour was observed in 5 cases. If there had been no effect by day 14, the patients were started on sirolimus at a dose of 0.05–0.2 mg/day which proved to be effective in all the patients (n = 4). Our study showed that sirolimus is effective in complex cases of chyloperitoneum and chylothorax in newborns and infants. Because of the rarity of these disorders, our conclusions were based on the analysis of a small cohort. To confirm our results and develop uniform diagnostic and treatment guidelines, further, more targeted multicenter research is needed. Until such guidelines are adopted, decisions on the treatment of chyloperitoneum and chylothorax should be made on an individual basis and approved by the medical committee of a treatment center.
The results of therapy with venetoclax, daratumumab and plerixafor as part of the conditioning regimen in chemotherapy-refractory acute leukemia in children
Authors: Klimentova M. A. , Shelikhova L. N. , Ilushina M. A. , Blagov S. L. , Perminova M. E. , Popov А. M. , Kashpor S. A. , Fadeeva M. S. , Olshanskaya Yu. V. , Glushkova S. Yu. , Pershin D. E. , Balashov D. N. , Maschan А. А. , Maschan M. A.
Published: October 2023

The main outcomes of allogeneic hematopoietic stem cell transplantation (HSCT) in chemotherapy-refractory acute leukemia remain suboptimal due to a high relapse rate. The incorporation of targeted anti-leukemia agents into the conditioning regimens is a potential approach to improve the efficacy of HSCT. We assessed the safety and potential efficacy of the addition of venetoclax, daratumumab, and plerixafor to the conditioning regimens in children with chemotherapy-refractory acute leukemias who received allogeneic TCRab/CD19-depleted HSCT. We used data from a pilot study, as well as the data of patients from a retrospective cohort who received similar therapy according to the individual indications. The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. All 43 patients (33 acute myeloid leukemias (AML), 8 T-cell acute lymphoblastic leukemias (T-ALL) and 2 acute leukemias of ambiguous lineage) had active disease status at the time of transplantation. The preparative regimen included myeloablative conditioning based on either total body irradiation or treosulfan or melphalan. A haploidentical related donor was used as a graft source in 38 cases, while a fully matched related or unrelated donor was used in 5 cases. The engraftment was observed in 93% of cases, no excessive toxicity was noted. MRD-negative complete remission was achieved in 37 patients (86%). The cumulative incidence of grade II–IV acute graft-versus-host disease (GvHD) was 10%, and the cumulative incidence of chronic GvHD was 5%. At 2 years, transplant-related mortality was 7%, relapse incidence was 52%, event-free survival was 41%, and overall survival was 51%. The overall survival rate for the AML group was 58% and 25% for the T-ALL group. Our data show that the addition of targeted agents to the conditioning regimens is safe, however, does not significantly improve the results of HSCT in the study cohort of patients.
Anthracycline-induced cardiotoxicity in a child with acute lymphoblastic leukaemia against the background of new coronavirus infection
Authors: Kondratiev G. V. , Melnikov M. E. , Kulyova S. A. , Chepelev A. S. , Bannova S. L. , Kornishina T. L. , Reshetnyak I. A. , Murasheva K. D.
Published: October 2023

Anthracycline chemotherapy drugs are widely used for the treatment of various tumors but they are associated with high cardiotoxicity. The novel coronavirus disease can also negatively affect the heart function. In this article, we report a case of anthracycline-related cardiotoxicity in a child with refractory acute lymphoblastic leukemia and the novel coronavirus disease, describing changes in instrumental and laboratory parameters observed over time during the treatment and providing a description of autopsy samples of the myocardium. The patient’s parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
Minimal residual disease monitoring in B-lineage acute lymphoblastic leukemia using flow cytometry. Guidelines of the Russian-Belarusian multicenter group for pediatric acute leukemia studies
Authors: Popov A. M. , Mikhailova E. V. , Verzhbitskaya T. Yu. , Movchan L. V. , Permikin Zh. V. , Shman T. V. , Karachunskiy A. I. , Novichkova G. A.
Published: October 2023

Multicolor flow cytometry is now routinely used in laboratory practice for minimal residual disease (MRD) monitoring in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). This article describes the methodology of MRD detection in BCP-ALL using flow cytometry as recommended by the Russian-Belarusian multicenter group for pediatric acute leukemia studies. This wellharmonized approach includes recommendations for the choice of monoclonal antibodies, sample preparation, cytometer setup, flow cytometry data analysis and interpretation as well as for reporting. These guidelines allow application of multicolor flow cytometry for MRD monitoring in BCP-ALL in children and adults both in local laboratories and in multicenter settings in prospective clinical trials.
Risk factors for coagulation inhibitor development in children with severe hemophilia A
Authors: Dmitriev E. V. , Liubushkin A. V.
Published: October 2023

Aim of the study: to examine the role of potential risk factors in inhibitor development in previously untreated patients (PUPs) (or minimally treated patients) with severe hemophilia A. The study was approved by the Independent Ethics Committee and the Scientific Council of the Belarusian Research Center for Pediatric Oncology, Hematology and Immunology (the Republic of Belarus). The study included 89 boys who underwent regular follow-up for severe hemophilia A at the Belarusian Research Center for Pediatric Oncology, Hematology and Immunology (the Republic of Belarus) from 1998 to 2022. The median age (10th–90th percentile) at diagnosis of hemophilia was 8.0 (1.0–21.0) months, the baseline factor VIII activity was 0.7% (0.4–0.95%). Age at first exposure to factor VIII concentrate was 11.0 (1.0–31.0) months. Out of 89 patients, 23 children had severe hemophilia A with inhibitors. The cumulative incidence of inhibitors in the whole group of PUPs was 31.0 ± 5.6%. The cumulative incidence of hemophilia A with inhibitors was higher in the patients with null mutations (37.0 ± 6.9%) than in the patients with non-null mutations (6.5 ± 6.0%) (the log-rank test, p = 0.041). The use of plasma-derived FVIII concentrate (approved for use in neonates and for prophylaxis) from one manufacturer was associated (c2 = 8.53; p = 0.004) with a lower incidence of factor VIII inhibitors (up to 21.3 ± 8.5%) compared with the incidence in the group of patients treated with FVIII concentrates from different manufacturers (45.2 ± 7.8%). Age (> 1 year old or < 1 year old) at first exposure to FVIII had no effect on the formation of inhibitors (the log-rank test, p = 0.746). Such factors as age at diagnosis of hemophilia (odds ratio (OR) 0.99; 95% confidence interval (CI) 0.93–1.024; p = 0.991) and baseline factor VIII activity (OR 0.99; 95% CI 0.8–1.06; p = 0.09) were not associated with inhibitor development. The first measurements of activated partial thromboplastin time (APTT) ratio (patient APTT value over the APTT reference value) (OR 1.89; 95% CI 0.72–5.09; p = 0.21) and FVIII recovery in vivo (OR 0.74; 95% CI 0.27–2.01; p = 0.55) were not associated with inhibitor development either. We have confirmed that one of the main risk factors for FVIII inhibitor development is F8 gene mutations. The incidence of inhibitors among the patients who received plasma-derived FVIII concentrates (recommended for use in PUPs in the neonatal period) from one manufacturer was lower than among those who received FVIII from different manufacturers.
The impact of interferon-gamma level on the health status of patients with sickle cell disease in Basrah
Authors: Ibraheim W. N. , Jasim H. A. , Abdullah A. S.
Published: October 2023

Sickle cell disease (SCD) is one of the most prevalent autosomal recessive diseases, characterized by the generation of abnormal hemoglobin S. Our study aimed to assess how the serum level of interferon-gamma affects the health status of patients with SCD in Basrah. A total of 90 participants were enrolled in this study and divided into two main groups: a SCD group and a control group. The SCD group included 30 patients with SCD in steady state and 30 patients with SCD in vasoocclusive crisis; the control group included 30 ageand sexmatched apparently healthy individuals. Approval was obtained from the Research Ethics Committee of the College of Medicine, University of Basrah before conducting the study. Two milliliters of venous blood were drawn from all the participants, and ELISA tests were utilized to determine the levels of serum interferon-gamma. There was a statistically significant increase in the serum level of interferon-gamma among SCD patients (both in steady state and in crisis) compared to the control group (p = 0.05). There were no significant differences in the levels of interferon-gamma between the patients in steady state and during vaso-occlusive crisis (p > 0.05). Interferon-gamma may influence the general health of sickle cell patients and contribute to the cause of inflammation, no matter whether the patient is in stable condition or is experiencing a crisis.