bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemerin/CMKLR1 Axis Induces Proliferation and Invasion in Human Endometrial Cancer
Authors: Wei Ding , Yang Gao , Wei Zhang , Pengpeng Qu
Published: June 2022

Objectives: This study aimed to analyze the differences in the chemokine chemerin and its receptor chemokine-like receptor 1 (CMKLR1) between endometrial cancer (EC) patients and normal populations, and investigate the effect of CMKLR1 on the proliferation, migration and invasion of HEC-1B cells and its roles in Wnt/ β-catenin signaling pathways. Methods: The clinical data of 50 EC cases (study group) admitted from January 2018 to December 2020 were collected, and 50 cases of those who underwent a health checkup in Tianjin Central Hospital of Gynecology and Obstetrics during the same period were selected and included in the control group. The relationship between serum chemerin levels and clinicopathological features, as well as the difference in CMKLR1 protein expression between cancer and para-carcinoma tissue were compared. RT-PCR and Western blot methods were adopted to detect CMKLR1 expression in different EC cell lines and normal endometrial cells. CMKLR1 shRNA and NC shRNA stably transfected cell lines were constructed by shRNA interference technology to verify the interference efficiency. CCK-8 count assay, cell scratch test and transwell chamber were used to detect the effects of silencing CMKLR1 gene expression on the proliferation, migration and invasion of EC cells. Changes in Wnt/β-catenin signaling pathways were detected after silencing CMKLR1 gene expression by Western blot. Results:The ELISA showed that the serum chemerin level in EC group was higher than that in normal control group. In EC group, the serum chemerin level in advanced-stage patients was higher than that in early-stage patients (P < 0.05). Immunohistochemistry showed that the CMKLR1 expression in EC tissue was higher than that in paracarcinoma tissue. Cytological findings showed that CMKLR1 expression was the highest in HEC-1B compared with normal endometrial cells (NE) and EC cell lines HEC-1A and Ishikawa, and the silencing efficiency of CMKLR1 gene in HEC-1B cells treated by shRNA interference technology reached 70%. CCK-8 assay showed that silencing CMKLR1 gene expression can significantly reduce the proliferation rate of HEC-1B cells (P < 0.05). The scratch test showed that silencing CMKLR1 expression genes significantly inhibit the migration of HEC-1B cells (P < 0.05). Transwell chamber showed that silencing CMKLR1 gene expression can inhibit the invasion ability of HEC-1B cells (P < 0.05). Western blot detection showed that silencing CMKLR1 gene expression can significantly inhibit the protein expression of phosphorylated β-catenin and cyclin D1 protein in HEC-1B cells, and the difference was statistically significant (P < 0.05). Conclusion: The chemokine chemerin and its receptor CMKLR1 may be involved in the progression and metastasis of EC. Serum chemerin levels can be used as a molecular marker for early diagnosis of EC, and CMKLR1 gene can provide a new target for the potential gene therapy of EC.
Interpretable Predictive Model for Shield Attitude Control Performance Based on XGBoost and SHAP
Authors: Hu Min , Zhang Haolan , Wu Bingjian , Li Gang , Zhou Li
Published: June 2022

The sudden decline in the attitude control performance is a common abnormal situation during shield tunneling. When the problem happens, the shield driver will have difficulty controlling the shield's attitude, which will cause the shield to deviate from its design axis and affect the quality of the tunnel. The causes behind poor control performance are usually complicated, so how to choose appropriate countermeasures is a challenging problem. Based on the above issues, this paper proposes the Interpretable Predictive Model for Shield attitude Control Performance (IPM_SCP). The model first predicts the current shield control performance through the extreme gradient boosting (XGBoost) sub-model and then uses the Shapley additive explanation sub-model to interpret the model output. The model was tested on the left-line tunnel of the Hangzhou–Shaoxing railway project in the Ke-Feng section. The results reveal that the model could effectively predict the control performance of the shield and give the most influential parameter and the direction in adjusting the parameter to improve the shield's attitude control performance when the control performance decreases. Therefore, IPM_SCP gives the correct parameter adjustment instructions when the shield’s attitude control performance declines, and eventually improves tunnel construction quality and efficiency.
Choroidal Hemodynamics in Central Serous Chorioretinopathy after Half-dose Photodynamic Therapy and the Effects of Smoking
Authors: Horiguchi Etsuyo , Takeuchi Jun , Tomita Ryo , Asai Keiko , Nakano Yuyako , Ota Hikaru , Taki Yosuke , Ito Yasuki , Terasaki Hiroko , Nishiguchi Koji M , Kataoka Keiko
Published: June 2022

This retrospective study aimed to evaluate choroidal hemodynamics after half-dose photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC) and the effects of smoking using laser speckle flowgraphy (LSFG). This study included 29 eyes of 29 patients treated with half-dose PDT for chronic CSC. The mean blur rate (MBR) in the PDT irradiation area (whole area), the pachyvessel (PV) area, non-PV (NPV) area, and filling delay (FD) area were assessed respectively. The MBR was also assessed by smoking status. The MBR significantly decreased in the whole, PV, NPV, and FD areas at all time points (P < 0.001). Of the 29 patients, 6 were never smokers, 13 were past smokers, and 10 were current smokers. At baseline, no significant difference was found in the MBR in the whole, PV, NPV, and FD areas among never, past, and current smokers. The MBR changes showed a significantly smaller decrease in current smokers than in never smokers in the whole (P = 0.021), PV (P = 0.009), and NPV (P = 0.034) areas, but not in the FD area (P = 0.172). Half-dose PDT for chronic CSC reduced choroidal blood flow in the PDT-irradiated area, which was blunted by current smoking status.
Use of plant growth regulators to reduce 2-methyl-4-chlorophenoxy acetic acid-Na (MPCA-Na) damage in cotton
Authors: Zhang Quancheng , Wang Jing , Wang Jun-Gang
Published: June 2022

Background2-methyl-4-chlorophenoxy acetic acid-Na (MPCA-Na) is a phenoxy carboxylic acid selective hormone herbicide that is widely used in crop fields. However, drift of MPCA-Na during application is highly damaging to cotton plants. This study was carried out from 2019 to 2020 to determine the effects of different concentrations of MPCA-Na on physiological metabolism and cotton yield at the seedling, budding, flowering and boll stages. Moreover, we evaluated the different combinations of brassinosteroids, gibberellin, phthalanilic acid and seaweed fertilizer, which used to ameliorate herbicide damage. ResultsMPCA-Na exposure caused a decrease in the chlorophyll content, and an increase in the soluble protein content, MDA content and protective enzyme activity. MPCA-Na also caused significant reductions in plant height, boll number and the single boll weight at the seedling and budding stages, but had little effect on plant height and the single boll weight at flowering and boll stages. Under the maximum recommended dose of MPCA-Na (130 g/L), the number of cotton bolls at seedling and bud stages decreased by 75.33% and 79.50%, respectively, and the single boll weight decreased by 46.42% and 36.31%, respectively. However, the number of cotton bolls and single boll weight at flowering and boll stages decreased by 48.15% and 5.38%, respectively. Application of plant growth regulators decreased the MDA content, and increasing chlorophyll, soluble protein content and protective enzyme activity, and reducing the degree of MCPA-Na damage. Positive effects were also observed in terms of cotton yield. ConclusionsThe results suggest that certain plant growth regulators could be used to alleviate MPCA-Na damage and maintain cotton yield. When the cotton exposed to MCPA-Na at the seedling stage should be treated with phthalanilic acid + seaweed fertilizer, while plants exposed at the budding stage should be treated with brassinosteroids + seaweed fertilizer, and those exposed at the flowering and boll stages should be treated with gibberellin + seaweed.
SparkGrid: Blockchain Assisted Secure Query Scheduling and Dynamic Risk Assessment for Live Migration of Services in Apache Spark based Grid Environment
Authors: G.M. Kiran , N Nalini
Published: June 2022

Grid computing is an emerging technology that enabled the heterogeneous collection of data and provisioning of services to the users. Due to the high amount of incoming heterogeneous request, grid computing needs an efficient scheduling to reduce execution time and satisfy Service Level Agreement (SLA) and Quality of Service (QoS) requirements. For that purpose, we proposed SprakGrid method to reduce execution time and satisfying SLA, QoS requirements. The proposed work includes four consecutive phases which are explained as follows, in first we perform user authentication in order to ensure the legitimacy of the users using Elliptic Curve based Chaos Theory (ECCT) algorithm which generate secret key and stored it into the blockchain. In second we perform query scheduling for resource discovery using Soft Actor Critic (SAC) algorithm by considering 3P’s parameters which is performed by spark environment that schedules optimal resources based on the service request. In third, we perform risk assessment and request dropping, in which the risk nodes of workers are evaluated by master node. To address the resource wastage by attacker, this research evaluates the risk value in a dynamic manner using Shannon entropy. Based on the risk assessment the requestsare classified into two classes such as normal and malicious. In fourth we perform service live migration, in which the malicious requests are dropped and normal request are migrated from source node to target node using Multi-Constraints based Emperor Penguin Optimization (MC-EPO). Finally, simulation is performed by GridSim and the simulation results demonstrate that the proposed SparkGrid method achieves superior performance compared to other state-of-the art methods.
Self-made fenestrated modified endograft for urgent an Aortic Arch Aneurysm: Case Report
Authors: Gallicchio Vito , Barbarisi Danilo , Condò Flavia , Sciarrillo Rosaria , Flora Loris
Published: June 2022

We report the case of an endovascular repair of an aortic arch aneurysm by a self-made endograft with a single fenestration in a high-risk patient unfit for open surgery. A patient of 81 years, chronic ischemic cardiopathic, suffering from prostate K in chemotherapy treatment, came to our hospital for post-traumatic fracture of the right femur, associated with dysphonia and respiratory disorders for several days. During the hospitalization, the patient performed angio-CT that found the presence of voluminous aneurysm of the aortic arch with a maximum diameter of about 70mm. The patient was treated in the first instance with a carotid-carotid-succlavium bypass to preserve the cerebral and upper limb vascularization. The self-made endograft was created by modifying a standard endograft by a single fenestration following the three-dimensional reconstructions of the CT images. The procedure was completed by implanting this endograft with stent delivery to the patient with a fenestration on the anonymous trunk. The procedure was successfully completed and postoperative course was uneventful. Computed tomography angiography demonstrated the exclusion of the aneurysm, patency of the implanted endograft modules, and absence of signs of endoleaks and / or cerebral or medullary ischemic complications.
Glycemic Response of Volunteers to the Consumption of Supplements and Food Formulas for Oral and/or Enteral Nutrition
Authors: Giuntini Eliana Bistriche , Ruffo Giovanna A , de Abreu Camila LM , Russo Marina C , Vidal Jady A A , Rocha Mariana V
Published: June 2022

PurposeThe objective of this study was to determine the glycemic index (GI) and glycemic load (GL) of three products from the Brazilian market used as supplement and food formula for oral and/or enteral nutrition.MethodsThe volunteers (n=16) attended Food Research Center weekly for six weeks, after a 10 h to 12 h overnight fasting, where their glycemic response was evaluated for 120 min, resulting from the consumption of glucose solution (reference food, three times) and three products: Cubitan® vanilla, Diasip® chocolate and Diasip® vanilla. GI was determined by calculating the area under the glycemic response curve using the trapezoidal rule and ignoring the areas below the fasting line and considering GI of glucose to be 100. To determine GL it was considered the amount of carbohydrates available in a standard serving of the product and GI.ResultsThe three products studied showed low GI and low GL (Cubitan® GI=35, GL=6; Diasip® chocolate GI=49, GL=7; Diasip® vanilla GI=47, GL=7), with significant differences from those and the reference food, but no significant difference between them. Similar results were also observed for the blood glucose peak, which occurred 30 min after the consumption of all products.ConclusionsGI and GL of the products were considerably lower than those of the reference food. The products evaluated presented a low glycemic response, showed by a glycemic response curve with a slightly accentuated shape and no high peaks.
Translocation of a single Arg9 peptide across a DOPC/DOPG(4:1) model membrane using the weighted ensemble method
Authors: Choe Seungho
Published: June 2022

A spontaneous translocation of cell-penetrating peptides(CPPs) in all-atom molecular dynamics(MD) simulations is not expected within a short time scale (e.g., a few hundred ns) because
it is believed that the time required for the translocation of usual CPPs is on the order of minutes. In this study, we report a single Arg9(R9) peptide translocation across a DOPC/DOPG(4:1) model membrane within an order of a few tens ns scale by using the weighted ensemble(WE) method, one of the most powerful and flexible path sampling techniques. We present free energy profiles of the translocation across the membrane and identify how water molecules play a role during the translocation. We also show how the orientation of Arg9 affects the translocation and how lipid molecules were transported along with Arg9. Our approach can help study interactions of CPPs with various model membranes within MD simulation approaches.
Determination of some heavy metal and mineral contents microbiological and chemical properties of Çökelek cheeses
Authors: Kalaycı Nagihan , Ürkek Bayram , Öztürk Feyza , Şengül Mustafa , Çiftçi Esengül
Published: June 2022

The Çökelek samples what 30 different, were collected from randomly local bazaars to investigate heavy metal contaminant and mineral levels and some physicochemical and microbiological properties of samples. The As was detected in the 4 of 30 samples, while the Pb was determined in the 6 of 30 samples. The mean major and trace element contents of Çökelek samples were ordered as Na > P > Ca > K > Mg and Al > Zn > Ni > Cu, respectively. The physicochemical properties indicated a high deviation among samples. The mean total solids, ash, salt, fat, protein waters soluble nitrogen contents and ripening index of samples were 29.83%, 1.88%, 0.68%, 4.31%, 19.84%, 0.33%, and 1.79%, respectively. The mean TAMB count of Çökelek samples were found as 8.26 log CFU g− 1. The coliform bacteria and yeast-mold counts were detected in 11 and 27 of 30 samples, respectively. The mean coliform and yeast-mold counts were 1.82 log CFU g− 1 and 7.11 log CFU g− 1, respectively. There are not mentioned traditional cheeses in the legal rules such as the Turkish Food Codex. So, there is no legal limit and standard production processes. This situation is a problem in terms of traditional cheese quality. For this reason, traditional cheese should perform a further studied, and determine the legal limits.
Design and assessment of pro-poor financial soft policies for expanding cities
Authors: Wang Chenbo , Cremen Gemme , Gentile Roberto , Galasso Carmine
Published: June 2022

Recent major earthquake disasters have highlighted the effectiveness of financial soft policies (e.g., earthquake insurance) in transferring seismic risk away from those directly impacted and complementing `hard' disaster risk mitigation measures. However, the benefits of existing financial soft policies are often not guaranteed. This may be attributed to: (1) their low penetration rate (e.g., in the case of earthquake insurance); (2) the fact that they typically neglect the explicit needs of low-income sectors in modern societies, who are often disproportionately impacted by natural-hazard driven disasters; and/or (3) their failure to consider the time-dependent nature of urban exposure. We contribute towards addressing these shortcomings by proposing a flexible framework for designing and assessing bespoke, people-centred, household-level, compulsory financial soft policies (including conventional earthquake insurance, disaster relief fund schemes, income-based tax relief scheme, or a combination of those) across cities under rapid urban expansion. The proposed framework leverages the Tomorrow's Cities Decision Support Environment, which aims to facilitate pro-poor disaster-risk-informed urban planning and design in developing country contexts. The framework specifically enables decision makers to strategically design and then assess the pro-poorness of mandatory soft policies, using innovative financial impact metrics that discriminate losses on the basis of income. We showcase the framework using the hypothetical expanding city, ``Tomorrowville", successfully identifying pro-poor seismic-risk-related financial soft policies for different instances in the lifetime of the urban system.
Ethnocultural Themes in the Media: Typological Review
Authors:   Penza State University, Reva Ekaterina K.
Published: June 2022

The relevance of the study is due to the ethnocultural diversity of the Russian Federation, which is reflected in the media, the action of the Strategy of the State National Policy of the Russian Federation for the period up to 2025, which, along with the existing directions, provides information support for state national policy, and the fact that thematically 2022 is the Year of folk art and intangible cultural heritage of the peoples of Russia. The article presents the results of qualitative analysis of media materials representing the traditional culture of the peoples of the Russian Federation. The empirical basis of the study is materials of all types of federal media for the period from 2013 to the present: periodical printing, television, radio, news agencies. On the basis of typological, institutional, functional analysis, the components of ethnoculture reflected in traditional media (traditions, customs, holidays, national cuisine, national costume, crafts and crafts) were identified, methods of representing the unique culture of the peoples of Russia (genres and formats, inclusion of information about the ethnoculture of the peoples of Russia in media materials with a different main theme). The functioning of ethnocultural topics is emphasized in television programs, the content of which is aimed at the development of domestic tourism, as well as in television reports on political topics. The article emphasizes that ethnoculture is an integral part of the life of the ethnos, which determines its philosophy and mental features. Media reflecting the specifics of the traditional culture of peoples are a tool for disseminating knowledge about their history and culture, a resource for fixing and storing information about the ethnocultural diversity of our country. Based on the definition of guardians of intangible culture, laid down in the Draft Law “On Intangible Ethno-Cultural Heritage of the Russian Federation”, this category is legitimate to include the institution of the media, which is of great importance in the formation of ethnographic literacy of the population and ensuring interethnic harmony. The topic is promising in the aspect of studying the media representation of the traditional culture of the peoples of the Russian Federation directly in the Year of Folk Art and the Intangible Cultural Heritage of Peoples and the subsequent qualitative and quantitative analysis of the reflection of ethnoculture in the media.
A three-dimensional model study of lateral pressure manifestation in gorge dump overburden
Authors: Khazaryan A. A.
Published: June 2022

Today the development of upland quarries with the formation of multi-tiered dumps of overburden rock mass in complex conditions of mountainous terrain and limited land resources still remains a problem. The conducted analysis has shown that the practice of designing of multi-tiered dumps in gorges lacks detailed consideration of the issues determining the stress distribution in the dump body depending on the dihedral angle formed by the slopes of the side faces of the gorge. The point is that the process of overburden dumping is accompanied with the transmission of stress forces to the central axial plane of the dump body formed in the gorge from the side of the gorge inclined surfaces. At the same time, the inclined component of stresses is due to the mass of overburden rocks dumped onto the inclined side surfaces of the gorge. Being directed at an angle to the shear forces acting in the dump, these lateral stresses play a positive role in the acceleration of rock mass consolidation in the clamped environment during the overburden dump formation. The decrease in dump shear forces leads to the increase in dump stability. It also allows to determine the rational volumes of overburden to be laid as well as the main parameters of a multi-tiered dump. It should be noted that there are significant difficulties in identifying and objective assessing the nature of occurrence and distribution of stress forces in the dump being constructed in the gorge using graphic-analytical methods. In the course of the presented study, the author made an attempt to identify and register stress forces in the body of a multi-tiered overburden dump formed in the gorge using physical modeling methods. For this purpose, a three-dimensional model test bench of a multi-tiered dump has been developed. This test bench allows to solve a three-dimensional problem using the method of physical modeling and, identify the stress variation patterns in the central axial plane of the dump model depending on the inclination angles of the side surfaces of the gorge.
Viability assessment of integrated P- and S-wave surveys using ultrasound
Authors: Hassan B.
Published: June 2022

Potential of, integrated geophysical, especially P- and S-wave combined near surface surveys, is assessed; demonstrated with use of sparingly, reduced chronographic i. e., time and velocity, (1 MHz) ultrasonic imaged data. Case of aqueous and non-aqueous, predominantly, fossil fuel origins spills seepage within near-surface geology is examined in terms of evaluation of possible complexities of fluids and surrounding interactions; which are experimentally simulated embodied as flow components of an immiscible displacement process. Such processes are understood and studied widely, within various, especially near-field geo- and engineering including environmental and also geo-disaster contexts. Interesting relevant scenarios, including aspects, of geological complexity of well known geographical locations while their subjugation also to various, whether natural or anthropogenic, stressors are presented alongside pertinent theory for better grasp, including plausibility, of methodology and inferring. Experimental analogues and geometrical constraints are explained in detail. Ultrasonic P- and S-wave, data in relevant context, also verified analytically, are comprehensively evaluated. S-wave data not only corroborates P-wave data attributes in time-space localization of displaced, from displacing phase, including a “dim spot”, an interesting artifact corresponding to interface (or mixed phase) region, S-wave also manifested other elastic and thermo-mechanical characteristics of the same feature. Further a flow rate, especially, that of injection, control or dependence of a planned displacement process was confirmed, for example if required in tracer and remedial studies. S-waves characteristic suitability to reveal other fluid-fluid and fluid-solid interaction peculiarities at micro and possibly at nano scale, as amplitude effects, is foreseen to assume significant promise.
Prostate specif c antigen density as a prognostic factor in patients with prostate cancer treated with combined hormonal radiation therapy
Authors: Kneev A. Y. , Shkol’nik M. I. , Bogomolov O. A. , Zharinov G. M.
Published: June 2022

Purpose. To evaluate prostate specifc antigen density (PSAD) as a predictor of overall (OS) and cancerspecifc survival (CSS) in patients with prostate cancer (PC) who have undergone combined hormonal-radiation therapy.

Material and Methods. In order to assess the prognostic signifcance of PSAD we retrospectively analyzed outcomes of 714 PCa patients who received combined hormonal-radiation therapy at the A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies, Ministry of Healthcare of Russia, between January 1996 and December 2016. Since the prognosis and management differ according to the extent of tumor involvement, patients were categorized into localized (n=272), locally advanced (n=231) and metastatic (n=211) PC groups. We equentially applied ROC-analysis, Kaplan-Meier product limit estimator and Cox proportional hazards model to assess the prognostic relevance and establish threshold values of PSAD that had a signifcant impact on survival rates.

Results. In the localized PC group, PSAD threshold values of 0.34 ng/mL/cc and 0.36 ng/mL/cc were associated with a decrease in OS and CSS, respectively. Patients with “low” PSAD had signifcantly better OS and CSS survival rates in both uni- and multivariate analyses. In locally advanced PC group, PSAD threshold values were 0.28 ng/mL/cc and 0.63 ng/mL/cc for OS and CSS, respectively. However, exceeding the specifed values, in the locally advanced PC group, was not accompanied by a statistically signifcant decrease in survival rates. Finally, in the metastatic PC group, established PSAD threshold values were 2.25 ng/mL/cc and 2.30 ng/mL/ccfor OS and CSS, respectively. According to the results of univariate analysis, patients with “low” PSA tend to demonstrate statistically signifcant better OS and CSS rates. The results of multivariate analysis, however, failed to prove PSAD as an independent prognostic factor within the metastatic PC cohort. Conclusion. PSA density is a reliable tool for assessing survival rates in patients with localized PC who have undergone combined hormonal-radiation therapy.
Investigation of Issues in Structural Flood Management Measures in Sri Lanka
Authors:   Department of Building Economics, University of Moratuwa, SRI LANKA, Dasandara Miyami , Ernst Rusiru ,   Department of Building Economics, University of Moratuwa, SRI LANKA, Kulatunga Udayangani ,   Department of Building Economics, University of Moratuwa, SRI LANKA, Rathnasiri Pavithra ,   Division of Building Science and Technology, City University of Hong Kong, HONG KONG
Published: June 2022

Floods can be identified as one of the devastating natural phenomena, which resulted in a considerable amount of social, economic and environmental impacts. Sri Lanka is a country that is highly vulnerable to floods due to its unique geographical location and topography. Many flood management measures, which mainly include structural and nonstructural have implemented to reduce the impact of floods. Among them, structural measures play a vital role in flood management. However, the failures in achieving the expected performance of these existing structural measures urge the need to identify issues with them and overcome those issues to enhance the flood management process in Sri Lanka. Hence, this study focused to investigate the issues related to structural flood management measures in Sri Lanka to bridge this knowledge gap. Initially, a literature review was conducted to gain a theoretical understanding of the research area. The research approach was qualitative, which was followed by two in-depth case studies. Semi-structured interviews were conducted with 10 industry experts to gather data. Collected data were analysed via content analysis. Empirical research findings revealed that structural measures play a prominent role in flood management. However, significant issues such as ageing of structural measures, leakages, construction faults, inadequate capacity, blocking of water flow and possibility of collapsing were identified in these existing structural flood management measures, which negatively impact the effectiveness of the overall flood management process within the country. The findings of this study will lead to gain a proper understanding of gaps and weaknesses in structural flood management measures in Sri Lanka and would influence the policymakers and other respective practitioners in disaster management to enhance structural flood management by using their novel ideas and concepts.
Safety Compliances Enhancement: Foreign Labours Behaviour in the Malaysian Construction Site
Authors:   Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Kajang, Selangor, MALAYSIA, Zulkeflee Azreen Ariff ,   Faculty of Architecture, Planning and Surveying, Universiti Teknologi Mara, Shah Alam, Selangor, MALAYSIA, Faisol Nasruddin ,   Faculty of Architecture, Planning and Surveying, Universiti Teknologi Mara, Shah Alam, Selangor, MALAYSIA, Ismail Faridah ,   Faculty of Architecture, Planning and Surveying, Universiti Teknologi Mara, Shah Alam, Selangor, MALAYSIA, Ismail Noor Akmal Adillah ,   Faculty of Architecture, Planning and Surveying, Universiti Teknologi Mara, Shah Alam, Selangor, MALAYSIA
Published: June 2022

Foreign labours workforce has long been dominating the Malaysian construction industry at the operational level as numerous occupational safeties literatures have reflected most of construction accidents are caused by poor human behaviours. Undeniably, the existence of proper safety behaviour would influence good safety compliance among the construction foreign labours. The purpose of this study is to examine the key issues affecting the safety compliance behaviour enhancement of construction foreign labours in the Malaysian construction site. For the present research, nine case studies were conducted by using semi-structured interviews to obtain data from the informants who are mainly site safety personnel. These personnel were working very closely with the construction foreign labours. The findings of this research reveals that there are five key issues that would influence the safety compliances enhancement among the foreign labours: (1) Emotional evoke, (2) Leader as example, (3) Forerunner within the same ethnicity, (4) Supervision execution and (5) Safety prioritisation. Therefore, these key issues have proven that there is a significant relationship between the workers' behaviours and consequences of an act.
Problematization of the phenomenon of social wellbeing
Authors: Kapralova E. A.
Published: June 2022

The article provides an review of problematization of social wellbeing. The author highlights the approaches to substantiating the definition of a phenomenon in various branches of knowledge based on the historical method and proposes to apply an interdisciplinary approach based on a divergent vision of the phenomenon as be the most relevant in the modern context of the socio-economic development of society. An important research aspect is the linguistic and semantic analysis of those forms that are used for the semantic expression of the phenomenon. The conceptualization of reality by an individual takes place with the help of the language and linguistic rules that are characteristic of certain societies. At the same time, the author outlines the difference between that the phenomena of wellbeing per se and social wellbeing. The paper also highlights the existential and meaning-forming aspect of social wellbeing. According to the author, the phenomenon of social wellbeing is a reflection of the cognitive movement of the individual and society on the way to the axiological reflection of the socio-cultural being of the individual. Herewith, constant transformation and changes in comprehension are possible, which may conflict with the accumulated experience or even ignore it.
THE EFFECT OF INTERNAL CONTROL SYSTEM ON TAX EFFECTIVENESS THROUGH THE STRENGTHENING OF TAX OBLIGATION IN TAX SERVICE OFFICES IN MAKASSAR CITY
Authors:   Sekolah Tinggi Ilmu Manajemen Publik Makassar., Hanafi Ali , H.M Irawati ,   Sekolah Tinggi Ilmu Manajemen Publik Makassar., Masniah Andi ,   Sekolah Tinggi Ilmu Manajemen Publik Makassar., Arlini Lidya ,   Sekolah Tinggi Ilmu Manajemen Publik Makassar.
Published: June 2022

The purpose of this study was to determine the effect of internal control systems and taxpayer compliance on tax effectiveness at the Tax Service Office in Makassar City. This research was conducted quantitatively and used a questionnaire as a means of collecting data. For testing hypotheses using Structural Equation Modeling analysis tools with the Smart-PLS Version 3.0 program. The population in this study were all tax employees at the Tax Service Office in Makassar City has 460 employees. The sampling technique uses purposive sampling. So that the sample used in this study was 127 samples from tax employee respondents in the Account Representative section, tax checking section and tax collection employee at the Makassar City Tax Service Office. The results of this study indicate that the internal control system has a significant positive effect on tax effectiveness, indicating that the internal control system of taxpayers is needed as a control to detect the number of tax deviations committed by taxpayers, taxpayer compliance has a significant positive effect on tax effectiveness, this indicates that the understanding and awareness of taxpayers regarding their tax obligations and the number of appeals by tax authorities (tax officers) to pay taxes in accordance with the provisions, the internal control system does not have a significant effect on WP compliance, indicating that the taxpayers internal control system is a more directed form of supervision to prevent the occurrence of misuse and tax fraud by the taxpayer and the taxpayers fall does not mediate the effect of the internal control system on tax effectiveness, indicating that a strengthening of the internal control system is more directed towards control or supervision, to prevent taxpayers from committing tax irregularities or tax fraud.
PSOAS ABSCESS:A RARE LOCALIZATION OF TUBERCULOSIS INFECTION
Authors: Azzouz Lotfi , Zohra Benmoula Fatima , Dahbi-Skali Laila , Baiss Marouane , Jalil Mdaghri , Said Benamar , Rahal Mssrouri , Settaf Abdellatif
Published: June 2022

Psoas abscess is a rare disease with various etiologies. The most common pathogen in primary abscess is Staphylo coccus aureus. Crohns disease is the most common cause of secondary abscess. Mycobacterium tuberculosis is considered an extremely rare cause of psoas abscess, The clinical manifestation is insidious, the classic symptoms are pain and fever. Computed tomography (CT) is the gold standard in the diagnosis and follow-up of retroperitoneal abscesses. The treatment of choice is percutaneous drainage guided by imagery. Surgical drainage should be reserved for cases of failure of percutaneous drainage, if possible via the extraperitoneal route, but in the event of a secondary abscess, the transperitoneal approach is preferred to correct the original disease.
COMPARATIVE EVALUATION OF ALTERNATE EMERGENCY FIXATIVES
Authors: Pandit Rumaisa , Singh Sanjeet , Singh Paramjit , Singh Nishant , Sharma Kanika
Published: June 2022

Fixation is the cornerstone of histopathology.In order to preserve the morphology of the tissue for further details its essential that all the components are preserved in a life like state. Formalin is the universal fixative but on account of its carcinogenic potential needs to be replaced by the alternate fixatives which are easily available.This study aims to assess and compare the efficacy of alternative fixatives like local anesthetic solution, normal saline , distilled water and life buoy hand sanitizer by using H & E stained sections. Total sample size of 100 sections was obtained from 10 paraffin embedded tissue blocks obtained from Indian goat tongue each fixed in LA solution ,Normal Saline, Distilled water, Hand sanitizer and in Formalin for 12 hour and 24 hour and named as group A and group B respectively. The sections were evaluated on five parameters and then subjected to statistical analysis.Kruskal wallis test, Mann Â–Whitney U test and Kappa Statistic were used .Significant difference was noted in the four alternate fixatives( < 0.05).On the basis of the results obtained , Local Anesthetic solution was found to be used as an alternate emergency fixative.
THYMOMA AS A NECK SWELLING - A SURGICAL DILEMMA
Authors:   Department of GeneralSurgery MGM Medical College, Navi Mumbai. MGM Institute of Health Sciences., A. Kalokhe Shifa , Saha Shaunak ,   Department of GeneralSurgery MGM Medical College, Navi Mumbai. MGM Institute of Health Sciences., Suraj Lisha ,   Department of GeneralSurgery MGM Medical College, Navi Mumbai. MGM Institute of Health Sciences., Kadam Sameer ,   Department of GeneralSurgery MGM Medical College, Navi Mumbai. MGM Institute of Health Sciences.
Published: June 2022

Thymomas are rare neoplasm of Anterior Mediastinum originating within the epithelial cells of the thymus and it is exceedingly uncommon in children and young adults, rises in incidence in middle age, and peaks in the seventh decade of life. One third to one half of patients present with an asymptomatic anterior mediastinal mass on chest radiograph, one third present with local symptoms (cough, chest pain, superior vena cava syndrome, and/or dysphagia), and one third of cases are detected during the evaluation of myasthenia gravis. Myasthenia gravis is a disease of the neuromuscular junction which causes progressive weakness of muscles. Indication of thymectomy for all cases of myasthenia gravis has been a topic of debate but thymectomy is indicated in all cases with thymomas no matter the stage of myasthenia gravis. We present a rare case of Thymoma as 70/Female patient presented with a painful lateral neck swelling on left side with Myasthenia Gravis and Dysphagia. We couldnt find any similar cases in literature. USG Neck was done which showed a 5.3x5.3x4.3cm multilobulated mass in left supraclavicular region inferior to left lobe of thyroid with calcification suspicious of malignancy which possible origin from Thyroid and Parathyroid Gland. On CECT scan there was 4.1x3.4x3.8 cm isodense mass which seems to be arising from lower pole of left thyroid lobe and extending in surrounding structures. FNAC was s/o Thymoma type A. Patient underwent Sternotomy- entire tumor along with thymus was dissected, however posteriorly it was densely adhered to Left Vagus Nerve Giving Suspicion of Neurofibroma. Specimen Sent for Frozen Section which confirmed it to be Type A thymoma. Histopathology Report concluded the diagnosis- Type A Thymoma. Post Operative was Uneventful. Thus, we conclude a rare case of Neck Swelling with series of event to reach to a Final Diagnosis of Thymoma.
CORRELATION BETWEEN RISK FACTORS AND CLINICAL OUTCOMES FOLLOWING INTRAARTICULAR INJECTION OF AUTOLOGOUS PLATELET RICH PLASMA IN EARLY OSTEOARTHRITIS KNEE
Authors:   Department of Physical Medicine and Rehabilitation, Government Kilpauk Medical College, Chennai., Sisha P. , Thirunavukkarasu P. ,   Department of Physical Medicine and Rehabilitation, Government Kilpauk Medical College, Chennai., Chitrarasu K. ,   Department of Physical Medicine and Rehabilitation, Government Kilpauk Medical College, Chennai.
Published: June 2022

Introduction: Osteoarthritis (OA) knee is one of the major cause of disability particularly in the elderly .Management of OA knee with intraarticular Platelet Rich Plasma (PRP) is an emerging new technique. Aim : Aim of our study was to assess the efficacy of intra-articular injection of platelet rich plasma (PRP) in knee osteoarthritis and to investigate the correlation between risk factors likeBody mass index ,ageandseverity of osteoarthritis with clinical outcome after intraarticular injection of platelet rich plasma Study setting : Department of Physical Medicine and Rehabilitation,Government Kilpauk medical college, Chennai, India, from March 2021 to January 2022. Materials and methods : 64 patients with mean age of 56.52 Â±7.53 who were diagnosed with grade 1 and 2 knee OA and who had undergone 2 doses of intraarticular injection of PRP were selected for the study and we retrospectively analysed the role of age, BMI, and Kellgren Lawrence grade of OA knee and their correlation with clinical outcome after intervention .Outcome measures used wereVAS and WOMAC scores Results: VAS and WOMAC scores before the procedure and final outcome after procedure using wilcoxn signed rank test showed that there was significant improvement in the outcome scores measured at followup done at 4th month . Subgroup analysis of patients stratified for age, Body mass index (BMI) and, KLgradewas performed for determining the individual effect of each risk factor on the outcome scores . It is found that the effect of PRP on people with BMI less than 25 ,KL grade 1 and age group <60 ,is significantly better than subjects with BMI more than 25 ,KL grade 2 and age group > 60 years. Conclusion: The use of intraarticular platelet-rich plasma definitely improves functional outcome in patients with OA and results in improved quality of life. Higher KL and risk factors like increased age, and BMI, has shown poorer outcome when compared to younger subjects , with lower BMI and KL grade , and hence modification in treatment protocol can be considered for such patients.
TEXT SUMMARIZATION USING PYTHON NLTK
Authors:   Assistant Professor, Prerna College of Commerce, Nagpur., Deshmukh Bharti
Published: June 2022

Text summarization is basically summarizing of the given paragraph with the use of natural language processing and machine learning. There has been an explosion in the quantity of textual content records from lot of sources. This quantity of textual content is a useful supply of facts and information which needs to be efficiently summarized to be useful. In this paper, the primary tactics to computerized textual content summarization were described. The distinctive approaches for summarization and the effectiveness and shortcomings of the distinctive methods were described. The machine works through assigning rankings to sentences withinside the document to be summarized, and the use of the maximum scoring sentences in the summary. Score values are primarily based totally on functions extracted from the sentence. A linear mixture of function rankings was used. Almost all the mappings from function to score and the coefficient values withinside the linear mixture were derived from a training corpus. Some anaphor decision was performed. In addition to primary summarization, a strive was made to address the issue of targeting the text at the user. The meant user was taken into consideration to have little history information or analyzing ability. The machine enabled through simplifying the individual words or phrases used in the summary and through drawing the pre-needful history facts from the web.
CORRELATION OF DENTAL IMPLANTS SURFACE TEXTURE AND OSSEOINTEGRATION Â€“ A REVIEW ARTICLE
Authors:   Intern, SGT University, Gurugram, Haryana., Chaudhary Shweta , Sachdeva Siddhant ,   Intern, SGT University, Gurugram, Haryana.
Published: June 2022

The key factor in success of dental implants is its ability to integrate with the surrounding bone, or in short, osseointegration. The events leading tosuccess or failure of osseointegration of a dental implant takes place mostly at the tissue- implant surface. It would be no doubt to say, that the implant surface offers the greatest potential to alter the process of osseointegration.Although the main purpose of surface modification of implants is to achieve better osseointegration, a shortened period of healing is desirable for both the clinician and the patient.
ZOUGLOU, SOCIAL COMMUNICATION AND POLITICAL SATIRE IN COTE DIVOIRE: EXAMPLE WITH TU SAIS QUI JE SUIS, LE PEUPLE TE REGARDE AND ON DIT QUOI BY YODE AND SIRO
Authors:   Universite Felix Houphouet-Boigny Abidjan-Cocody UFR Informations, Communication et Arts (UFRICA)., Oi Kouakou Benoit Kouakou , Atchory Albert Djedjess ,   Universite Felix Houphouet-Boigny Abidjan-Cocody UFR Informations, Communication et Arts (UFRICA).
Published: June 2022

This studyfocuses on threesatiricalsongs - Tu sais qui je suis, Le peuple te regarde and On dit quoi - by the Zouglou singers Yode and Siro. Understood within a music-media framework, these songs are presented as vectors of social communication. The analysis of the three songs is thus of interest to both Information and Communication Sciences and musicology. From a methodological point of view, the study opts for qualitative content analysis and is based on a corpus composed of the songs mentioned above. At the theoretical level, it uses satire theory and hermeneutics. The results of the analysis of the corpus reveal that the songs have consistently and uncompromisingly satirized the regimes of the three elected presidents who have led the country since the first president Felix Houphouet-Boigny. These are Presidents Henri Konan Bedie, Laurent KoudouGbagbo and AlassaneDramaneOuattara. In a style that is their own, and that is specific to the zouglou musical genre, the two singers have vigorously and boldly told each president their truth, criticising Konan Bedie for his concept of Ivoirite (Ivorianness) and its shortcomings, speaking out against Laurent Gbagbos laxness towards the mismanagement and other misbehaviors of his collaborators, and questioning AlassaneOuattara, among others, on his policy of ethnic catching up and precarity. Clearly, in the three songs, Yode and Siro talk to challenge the three personalities, but also to raise peoples awareness.
El sicariato: ¿una nueva cara para Panamá?
Authors: López Sinisterra Omar O.
Published: June 2022

El Sicariato, una forma criminal importada en Panamá, hoy día causa gran impacto y preocupación  en el país. Inicialmente se realizaron contratos a sicarios extranjeros para perpetrar este tipo de crimen, sin embargo, en pocos años los pandilleros pertenecientes a bandas locales iniciaron su oficio como sicarios por diversas causas. Panamá desde hace décadas se ha constituido en un hub de las drogas en tránsito desde Sur América transitando hasta México y Estados Unidos. La situación de muertes por sicariato se ha recrudecido en el país durante la pandemia, de tal forma que ha sido difícil controlarlo y ha creado gran inquietud social. El sicariato nace en nuestro país en el 2003 y primariamente ejecutado por sicarios suramericanos, y finalmente aquellos facilitados por las pandillas vinculadas al narcotráfico en el país. Esta modalidad criminal está cada día cobrando más víctimas entre ellas una gran cantidad de jóvenes. No se respeta lugar u hora para concretar el hecho fatal, además no se considera si la víctima está sola o se encuentra acompañada en reuniones o fiestas, lo que genera bajas colaterales que muchas veces no tienen relación con el objetivo. En Panamá las estadísticas muestran un aumento de las víctimas por el sicariato dadas las rivalidades entre pandillas, los tumbes de droga, ajuste de cuentas, crímenes y actos de intimidación y venganza que ya ocurren en cualquier escenario en el país.