bluuebunny/crossref_metadata_2025 huggingface dataset:
Total digital workflow in the fabrication of a partial removable dental prostheses: A case report
Authors: Mendes Teresa Almeida , Marques Duarte , Lopes Luis Pires , Caramês João
Published: August 2019

This report describes a clinical and laboratory protocol used in the fabrication of a removable partial dental prosthesis with a digital workflow in a 73-year-old patient. The metal framework was produced with a selective laser melting technique. For quality assurance and discrepancy analysis, the framework was superimposed and compared to the respective digital design file, and the printed model was also compared to the digital impression and rendered as a 3D colour map. Differences were detected in the framework on the clasp of tooth 17 (upper right second molar) and on the printed model on the interproximal surfaces of the abutments, particularly on tooth 17 and palatine area. The use of this digital workflow allowed for the achievement of an removable partial dental prosthesis with a good fit and occlusion with minimal adjustments, with the reduction of both clinical and laboratory time. Further studies are needed to gain a better understanding of these techniques.
Posterior Reversible Encephalopathy Syndrome Secondary to Hypertensive Encephalopathy Brought on by a MAO Inhibitor: A Case Report
Authors: Strother Robert , Wong Hailon , Miller Nathaniel E.
Published: August 2019

An elderly woman was admitted to the Family Medicine inpatient service for altered mental status after being brought to the emergency room by a concerned neighbor, who had come across the patient speaking incoherently. Initial evaluation was notable for elevated blood pressures, but extensive lab testing and head computed tomographic imaging were within normal limits. However, subsequent magnetic resonance imaging showed white matter changes consistent with posterior reversible encephalopathy syndrome (PRES), a neurologic syndrome characterized by headache, altered mental status, loss of vision, and seizures as well as radiographic findings of posterior cerebral white matter edema. Multiple etiologies of PRES have been described and include hypertensive encephalopathy, immunosuppressant medications, and eclampsia. This case describes an episode of PRES secondary to hypertensive encephalopathy brought about by an inappropriate dose of a monoamine oxidase (MAO) inhibitor. The patient had significant improvement in symptoms with removal of the offending agent and control of her blood pressure. While PRES generally has a good prognosis, prompt recognition, and management are important in preventing significant disease morbidity and mortality.
College Selectivity, Subjective Social Status, and Mental Health in Young Adulthood
Authors: Uecker Jeremy E. , Wilkinson Lindsay R.
Published: August 2019

Research on education and mental health has focused primarily on the benefits of higher levels of educational attainment. Other aspects of education, such as college selectivity, may also be associated with mental health, and higher subjective social status (SSS) is a potential pathway through which college selectivity and mental health could be linked. Using data from the National Longitudinal Study of Adolescent to Adult Health, this study (a) examines whether college selectivity influences mental health independent of objective measures of socioeconomic status and (b) assesses the role of SSS in this relationship. Among college graduates, attending a more selective college is associated with higher ratings of SSS, which in turn are associated with fewer depressive symptoms and lower perceived stress and anxiety. These findings contribute to our understanding of the role of college selectivity and SSS in the mental health of young adults.
The Analysis of the Implementation of 5-S Principles Integrated With ISO 9001 Requirements at Higher Education Level
Authors: Nurcahyo Rahmat , Apriliani Fany , Muslim Erlinda , Wibowo Alan Dwi
Published: August 2019

Indonesia, as a country with intensive skill positions, needs to pay attention to the management of colleges. Standardization and development are essential processes in higher education. These can be achieved through the implementation of total quality management (TQM). The initial steps to achieve TQM in higher education are the 5-S kaizen principles ( Seiri/Sort, Seiton/Set in order, Seiso/Shine, Seiketsu/Standardize, dan Shitsuke/Sustain) and ISO 9000. There are many similarities between the requirements of the quality management system (QMS) standard of ISO 9001 and 5-S principles. Thus, the integration of both systems in higher education is very potential to be implemented. This research was conducted at college Diploma Program. The implementation of 5-S principle integrated with the requirements of ISO 9001 used Analytical Hierarchy Process, Cross-Tabulation Correlation, and Importance Performance Analysis. The results of this research show the priority degree of 5-S principles on ISO 9001 requirements. It is also found that there is a close relationship (correlation value) between each 5-S principle and ISO 9001 requirements, and the results of the performance evaluation of the implementation of the integration system in college.
The Moderating Role of Psychological Flexibility in the Relationship Between Organizational Commitment, Workaholism, Job Security, and Corporate Entrepreneurship Among Information Technology Workers in Accra, Ghana
Authors: Boatemaa Maame Afua , Oppong Asante Kwaku , Agyemang Collins Badu
Published: August 2019

The present study was conducted to investigate the moderating role of psychological flexibility in the relationship between organizational commitment, workaholism, job security, and corporate entrepreneurship among information technology workers in Accra, Ghana. A total of 248 information technology workers purposively selected completed the Organizational Commitment Scale, the Dutch Work Addiction Scale, Job Insecurity Scale, the Work-Related Acceptance and Action Questionnaire, and the Entrepreneurial Behavior Scale. The results showed that job security, workaholism, and organizational commitment significantly predicted corporate entrepreneurship. Psychological flexibility moderated the relationship between organizational commitment, workaholism, and corporate entrepreneurship but not the relationship between job security and corporate entrepreneurship. The findings underscore the need for the development of interventions that would increase psychological flexibility in organizational settings.
The economic impact of biosimilars in Italy: a scenario analysis
Authors: Mennini Francesco S , Marcellusi Andrea , Bini Chiara , Rotundo Maria Assunta , Giunta Alessandro , Gasbarrini Antonio , Valesini Guido , Canonico Pier Luigi , Novellino Ettore , Orlando Valentina , Mecozzi Alessandra , Gamucci Teresa , Pagano Livio , Di Brino Eugenio , Ruggeri Matteo , Cicchetti Americo
Published: August 2019

Background:

the first generation of biotechnology drugs is reaching, or has already reached, the patent expiry and a large number of biosimilars is entering the Italian pharmaceutical market. The objective of the analysis was to evaluate the economic impacts of biosimilars on the national health expenditure in Italy between 2014 and 2020.

Methods:

Based on the information deriving from consumption per standard unit and equivalent patients, it was estimated monthly expenditure for some of the biological drugs currently available in Italy that have had or will have a patent expiry within the analysis period (infliximab, etanercept, adalimumab, insulin glargine, trastuzumab, rituximab, bevacizumab and insulin aspart). Pharmaceutical expenditure was calculated on hospital sales prices net of transparent discounts required by law and visible from the AIFA database. Three alternative scenarios have been developed based on the perceptions of a board of clinical experts, pharmacologists and pharmacoeconomists involved in the study. The experts involved analyzed the estimates of treated patients between 2014 and 2017 and reports their hypothetical biosimilar penetration during the period 2018-2020. The results were represented as the difference between the estimated expenditure in the absence of biosimilars and the estimated expenditure in the presence of biosimilars with the real or hypothetical biosimilar penetration.

Results:

considering the standard units dispensed for each year, the economic model estimate an annual expenditure in 2014 equal to € 1.47 billion for the molecules considered in the analysis. These estimates rise to € 1.54, € 1.50 billion and € 1.51 billion during 2015, 2016 and 2017 in the scenario without biosimilar introduction. Biosimilar introduction generates cost savings between € 3.8 million in 2015 and € 32.9 million in 2017 if compared with the scenario without. Assuming an increasing biosimilar penetration between 2018 and 2020, scenario analysis estimates a cumulative cost reduction equal to € 597 million.

Conclusions:

Overall, biosimilar penetration generates important cost reduction that could be re-invested in the National Health Sistem.
Leptomeningeal Carcinomatosis From Carcinoma of Unknown Primary in a Young Patient: A Case Report and a Literature Review
Authors: Moosavi Leila , D’Assumpcao Carlos , Bowen Jonathan , Heidari Arash , Cobos Everardo
Published: August 2019

Leptomeningeal carcinomatosis, leptomeningeal meningitis, or, as referred here, leptomeningeal metastasis (LM), is a rare but frequently fatal complication seen in advanced stage of cancer either locally advanced or after a metastasis of a known primary cancer. We present a rare and uncommon case of leptomeningeal metastases from carcinoma of unknown primary. A 32-year-old female was diagnosed with LM; however, no known primary carcinoma was identified after 2 separate biopsies. The first biopsy of the right pre-tracheal lymph node showed poorly differentiated pan-keratin (AE1 and AE3) and placental alkaline phosphatase with the possibility of germ cell origin. Second cytology of cervical lymphadenopathy was remarkable for cytokeratin 7 and 20, placental alkaline phosphatase, and CDX2 suggestive of germ line tumor with both mucinous ovarian and gastrointestinal carcinomas. Unfortunately, the LM progressed rapidly despite multiple cycles of germ cell origin directed systemic and intrathecal chemotherapy, and the patient opted for hospice care without getting a chance to identify the primary source.
Motivating Language Intensity: A Study of Wyoming Superintendents Motivating Language Use as Perceived by Their Principals
Authors: Holmes William T. , Parker Michele A.
Published: August 2019

The purpose of this study was to extend the field of motivating language theory (MLT) by providing a conceptual framework and methodology for determining low-ML and high-ML leader levels. This quantitative study, specifically, studied the Motivating Language of Wyoming K-12 superintendents operating in the role of CEOs as perceived by their principals. The results of this study found that Wyoming Superintendents with high-ML levels positively influencing employee outcomes in the areas of communication satisfaction, communication competence as well as organizational outcomes in the area of leader effectiveness. Finally, because of this study, two nascent ideas of leaders and leadership within the context of MLT have emerged: (a) the ML Intensity Score Composition and (b) the 3-D MLT Typology Matrix.
Determinants of Seasonal Influenza Vaccine Uptake Among the Elderly in the United States: A Systematic Review and Meta-Analysis
Authors: Okoli George N. , Abou-Setta Ahmed M. , Neilson Christine J. , Chit Ayman , Thommes Edward , Mahmud Salaheddin M.
Published: August 2019

Background: Despite the availability of a universal influenza vaccination program in the United States and Canada, seasonal influenza vaccine (SIV) uptake among the elderly remains suboptimal. Understanding the factors that determine SIV uptake in this important population subgroup is essential for designing effective interventions to improve seasonal influenza vaccination among the elderly. We evaluated the determinants of SIV uptake in the elderly in the United States and Canada. Methods: We systematically searched relevant bibliographic databases and websites from 2000 to 2017 for population-based clinical trials or observational studies conducted in community-based elderly individuals in the United States or Canada, irrespective of health status. Two reviewers independently screened the identified citations for eligibility using a two-stage sifting approach to review the title/abstract and full-text article. We gathered data on determinants of uptake (any vaccine receipt) and adherence (receipt of vaccine in more than one season) to seasonal influenza vaccination. Where possible, we pooled the data using inverse variance methods to minimize the variance of the weighted average. Results: Five cross-sectional studies on SIV uptake (none on adherence) from the United States met our eligibility criteria. Being older (pooled odds ratio [POR] = 1.44, 95% Confidence Interval [CI] = 1.11, 1.86); White (POR = 1.33, 95% CI = [1.10, 1.64]); and having higher income (POR = 1.06, 95% CI = [1.04, 1.09]); and health insurance (POR = 1.40, 95% CI = [1.25, 1.55]) were associated with increased SIV uptake. Conclusion: Older, ethnically White, higher income elderly individuals with access to health insurance coverage and a regular health care provider have higher SIV uptake in the United States. There was limited evidence for other socioeconomic and health-related determinants. Further studies are needed to provide an evidence base for planning more effective influenza vaccination programs in the United States.
Operative Versus Nonoperative Management of Appendicitis: A Long-Term Cost Effectiveness Analysis
Authors: Sceats Lindsay A. , Ku Seul , Coughran Alanna , Barnes Britainy , Grimm Emily , Muffly Matthew , Spain David A. , Kin Cindy , Owens Douglas K. , Goldhaber-Fiebert Jeremy D.
Published: August 2019

Background. Recent clinical trials suggest that nonoperative management (NOM) of patients with acute, uncomplicated appendicitis is an acceptable alternative to surgery. However, limited data exist comparing the long-term cost-effectiveness of nonoperative treatment strategies. Design. We constructed a Markov model comparing the cost-effectiveness of three treatment strategies for uncomplicated appendicitis: 1) laparoscopic appendectomy, 2) inpatient NOM, and 3) outpatient NOM. The model assessed lifetime costs and outcomes from a third-party payer perspective. The preferred strategy was the one yielding the greatest utility without exceeding a $50,000 willingness-to-pay threshold. Results. Outpatient NOM cost $233,700 over a lifetime; laparoscopic appendectomy cost $2500 more while inpatient NOM cost $7300 more. Outpatient NOM generated 24.9270 quality-adjusted life-years (QALYs), while laparoscopic appendectomy and inpatient NOM yielded 0.0709 and 0.0005 additional QALYs, respectively. Laparoscopic appendectomy was cost-effective compared with outpatient NOM (incremental cost-effectiveness ratio $32,300 per QALY gained); inpatient NOM was dominated by laparoscopic appendectomy. In one-way sensitivity analyses, the preferred strategy changed when varying perioperative mortality, probability of appendiceal malignancy or recurrent appendicitis after NOM, probability of a complicated recurrence, and appendectomy cost. A two-way sensitivity analysis showed that the rates of NOM failure and appendicitis recurrence described in randomized trials exceeded the values required for NOM to be preferred. Limitations. There are limited NOM data to generate long-term model probabilities. Health state utilities were often drawn from single studies and may significantly influence model outcomes. Conclusion. Laparoscopic appendectomy is a cost-effective treatment for acute uncomplicated appendicitis over a lifetime time horizon. Inpatient NOM was never the preferred strategy in the scenarios considered here. These results emphasize the importance of considering long-term costs and outcomes when evaluating NOM.
Cost-Effectiveness of Treatments in Children With Attention-Deficit/Hyperactivity Disorder: A Continuous-Time Markov Modeling Approach
Authors: Freriks Roel D. , Mierau Jochen O. , van der Schans Jurjen , Groenman Annabeth P. , Hoekstra Pieter J. , Postma Maarten J. , Buskens Erik , Cao Qi
Published: August 2019

Objectives. This study aimed to assess the cost-effectiveness of treatments for attention-deficit/hyperactivity disorder (ADHD) in children through prevention of serious delinquent behavior. Cost-effectiveness was assessed in net-monetary benefit (NMB). Methods. To evaluate the three major forms of ADHD treatment (medication management, behavioral treatment, and the combination thereof) relative to community-delivered treatment (control condition), we used data from 448 children, aged 7 to 10, who participated in the National Institute of Mental Health’s Multimodal Treatment Study of Children with ADHD. We developed a three-state continuous-time Markov model (no delinquency, minor to moderate delinquency, serious delinquency) to extrapolate the results 10 years beyond the 14-month trial period at a 3% discount rate. Serious delinquency was considered an absorbing state to enable assessment in life-years (LYs) of serious delinquent behavior prevented. The willingness-to-pay (WTP) threshold was set equal to the annual cost associated with serious delinquency in children with ADHD of $12,370. Results. Modeled and observed outcomes matched closely with a mean difference of 6.9% in LYs of serious delinquent behavior prevented. The economic evaluation revealed a NMB of $95,449, $88,553, $90,536 and $98,660 for medication management, behavioral treatment, combined treatment, and routine community care, respectively. Estimates remained stable after linearly increasing the WTP threshold between $0 and $50,000 in the deterministic sensitivity analyses. Conclusions. This study assessed the cost-effectiveness of treatments for ADHD in children using continuous-time Markov modeling. We show that treatment evaluation in broader societal outcomes is essential for policy makers, as the three major forms of ADHD treatment turned out to be inferior to the control condition.
Evolving Toward Shared HIV Care Using the Champlain BASE eConsult Service
Authors: Kendall Claire E. , Porter Janessa E. , Shoemaker Esther S. , Seoyeon Kang Rachel , Fitzgerald Michael , Keely Erin , Afkham Amir , Crowe Lois , MacPherson Paul , Rosenes Ron , Lundrigan Philip , Bibeau Christine , Liddy Clare
Published: August 2019

Background. Electronic consultation (eConsultation) is a potential strategy to improve access to specialist expertise and facilitate collaborative care models. The Champlain BASE eConsult service allows for asynchronous communication between primary care providers (PCP) and specialists on a secure, web-based system. HIV experts accessible include HIV physician specialists, HIV pharmacists, and social workers with expertise in HIV. Objective. This study aims to describe the use, value, and utility of this eConsultation service in the care of people living with HIV and to characterize the common question types and clinical topics asked by PCPs. Methods. We analyzed the data from eConsults sent to the HIV specialty group in Ontario’s Champlain Local Health Integration Network between February 2015 and December 2017. Usage data and close-out survey responses were analyzed using descriptive statistics, eConsults were classified using a predefined list of validated taxonomy, and a thematic analysis was performed on the consultation logs to identify common clinical themes. Results. Among the 46 eConsults, the most common question type related to drug treatment (58.7%, n = 27) and management (19.6%, n = 9). The main clinical themes involved the care of significant complexities in people living with HIV, such as comorbidities and drug interactions, and suggestions of coordinated patient care. As well, eConsult was used for advice regarding pre-exposure prophylaxis for HIV-negative patients at risk of HIV infection. PCPs highly valued the eConsult service (average rating 4.8/5). Conclusion. Overall, this study demonstrates that eConsult provides an efficient and valuable service to PCPs caring for patients living with or at risk for HIV by improving access to HIV specialists and facilitating the delivery of team-based comprehensive care.
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
Authors: Lindström Sara , Wang Lu , Smith Erin N. , Gordon William , van Hylckama Vlieg Astrid , de Andrade Mariza , Brody Jennifer A. , Pattee Jack W. , Haessler Jeffrey , Brumpton Ben M. , Chasman Daniel I. , Suchon Pierre , Chen Ming-Huei , Turman Constance , Germain Marine , Wiggins Kerri L. , MacDonald James , Braekkan Sigrid K. , Armasu Sebastian M. , Pankratz Nathan , Jackson Rebecca D. , Nielsen Jonas B. , Giulianini Franco , Puurunen Marja K. , Ibrahim Manal , Heckbert Susan R. , Damrauer Scott M. , Natarajan Pradeep , Klarin Derek ,   The Million Veteran Program, de Vries Paul S. , Sabater-Lleal Maria , Huffman Jennifer E. ,   The CHARGE Hemostasis Working Group, Bammler Theo K. , Frazer Kelly A. , McCauley Bryan M. , Taylor Kent , Pankow James S. , Reiner Alexander P. , Gabrielsen Maiken E. , Deleuze Jean-François , O'Donnell Chris J. , Kim Jihye , McKnight Barbara , Kraft Peter , Hansen John-Bjarne , Rosendaal Frits R. , Heit John A. , Psaty Bruce M. , Tang Weihong , Kooperberg Charles , Hveem Kristian , Ridker Paul M. , Morange Pierre-Emmanuel , Johnson Andrew D. , Kabrhel Christopher , Trégouët David-Alexandre , Smith Nicholas L.
Published: August 2019

In this work related to familial aggregation of familial venous thromboembolism, the investigators report genomic and transcriptomic association of 16 novel susceptibility loci for venous thromboembolism.
Focused Transesophageal Echocardiography for Bedside Diagnosis of Iatrogenic Cardiac Perforation: A Case Report
Authors: Yeoh Cindy B. , Fischer Gregory W. , Tollinche Luis E.
Published: August 2019

We describe an extremely rare complication of chest tube placement and focused transesophageal echocardiography (TEE) in the diagnosis of a life-threatening condition. It illustrates the value and utility of point-of-care ultrasound (POCUS) by way of a focused TEE in confirming a diagnosis and contributing toward the expeditious operative management of a life-threatening scenario. POCUS continues to gain traction in the field of anesthesiology. However, incorporation of POCUS training into curriculum of anesthesia residency programs is still in the infancy stages. Our report demonstrates the need for development and standardization of POCUS training for anesthesiologists in the perioperative setting.
Assessment of the Neutrophil-Lymphocyte Ratio in Classic Hodgkin Lymphoma Patients
Authors: Doğan Ali , Demircioğlu Sinan
Published: August 2019

Background and Objective: Besides known risk scoring systems, studies have recently been conducted in relation to NLR to estimate the prognosis of HL. Some studies found a relationship of NLR with PFS and OS. Our objective was to investigate whether NLR, as an inexpensive and easily accessible test, is a prognostic marker for cHL, as in several previous studies.

Methods: The study included 232 patients in the age range of 18 to 88 years who were diagnosed with classic Hodgkin Lymphoma and received ABVD chemotherapy and/or radiotherapy at Van Yuzuncu Yil University Hematology Clinic from 2000-2018. Analyses were conducted on the disease stage, risk scores, treatment responses and relapse statuses at the time of diagnosis based on the patients’ NLR values at the time of diagnosis.

Results: The mean age of the patients was 39.27 ± 15.90, while 38.8% were female and 61.2% were male. The NLR value at the time of diagnosis was significantly related to stage (p:0.013), early-stage risk score (p:0.022) and treatment response (p:0.032). The cutoff value of NLR was found as 4.23. The Hb value at the time of diagnosis was significantly related to stage (p:0.00), early-stage risk score (p:0.007), treatment response (p:0.006) and the latest status of patients (p:0.005).

Conclusion: High NLR values were found to be significantly related to disease stage, early-stage risk scoring and response to the treatment. These findings need to be supported by prospective studies with larger samples for these data to be used prognostic scores.

doi: https://doi.org/10.12669/pjms.35.5.601

How to cite this:Dogan A, Demircioglu S. Assessment of the Neutrophil-Lymphocyte Ratio in Classic Hodgkin Lymphoma Patients. Pak J Med Sci. 2019;35(5):1270-1275. doi: https://doi.org/10.12669/pjms.35.5.601

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
MicroRNA-21 as a diagnostic marker for hepatocellular carcinoma: A systematic review and meta-analysis
Authors: Qu Juan , Yang Jizhi , Chen Ming , Cui Lihong , Wang Tianxi , Gao Wei , Tian Jingjing , Wei Rongna
Published: August 2019

Background: MicroRNA-21 (miR-21) is one of the oncogenic miRNAs which may be a potential diagnostic biomarker for hepatocellular carcinoma (HCC).

Methods: We systematically searched Medline, Embase, the Cochrane Library, ISI Web of Knowledge, Scopus from inception to August 15, 2018, and reference lists of identified primary studies. Two independent investigators extracted patient and study characteristics. The sensitivity and specificity of microRNA-21 for HCC detection and were analyzed with a random effect model. The area under summary receiver operating characteristic curve (AUC) was used to estimate overall test performance.

Results: A total of 515 HCC patients, and 338 healthy or chronic hepatitis controls from six published studies were enrolled in this meta-analysis. All articles were published in English with moderate-to-high quality. The overall pooled sensitivity and specificity were 85.2% (73.3% to 88.4%) and 79.2% (68.4% to 87.0%), respectively. The AUC area was 0.89 (95% CI: 0.85-0.91). The studies had moderate heterogeneity (I2=70.11%). None of the subgroups investigated-ethnicity, controls, sample source-could account for the heterogeneity.

Conclusion: MiR-21 is a helpful biomarker for early diagnosis of HCC. Nevertheless, the results of the test must be interpreted carefully in the context of medical history, erological tests and imaging examinations for HCC surveillance.

doi: https://doi.org/10.12669/pjms.35.5.685

How to cite this:Qu J, Yang J, Chen M, Cui L, Wang T, Gao W, et al. MicroRNA-21 as a diagnostic marker for hepatocellular carcinoma: A systematic review and meta-analysis. Pak J Med Sci. 2019;35(5):1466-1471. doi: https://doi.org/10.12669/pjms.35.5.685

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Poetic licence to write resistance: women resisting intimate partner violence through poetry
Authors: Donovan Andrea Merriam , Dubrasky Danielle , Sorensen Scott , Corser Grant
Published: August 2019

The poetry therapy programme discussed describes work alongside members of a rural women’s support group addressing intimate partner violence. This approach contributes to social work theory/practice by expanding understandings of how women resist violence and affirms a tenet of Response-Based Practice: ‘alongside each history of violence there runs a parallel history of prudent, determined, and often creative resistance’ (Wade, 1997: 23). This approach to creative group-based work supports ‘positive social responses’ to women resisting intimate partner violence, expanding the ways in which social workers can respond to survivors of violence (Richardson and Wade, 2009: 209). Subtle and safer responses to violence are undervalued by dominant therapeutic practices. Response-Based Practice maintains that violence is resisted on a spectrum and that less noticeable forms of resistance are well reasoned and maintain dignity. This article describes how combining poetry therapy with Response-Based Practice can disrupt notions of resistance as solely outwardly expressed and large-action-oriented.
Extinction Rebellion: social work, climate change and solidarity
Authors: Booth Ella
Published: August 2019

Extinction Rebellion is a non-violent direct-action group that aims to put pressure on governments to take action on the climate crisis. This article introduces the organisation, their message and tactics, and describes some experiences of the ‘International Rebellion’ in London at the end of April 2019. It suggests that social workers have a duty to act in solidarity with those most affected by climate change and that Extinction Rebellion offers a promising model for change.
Child protection and family group conferencing curriculum for social workers in Palestine
Authors: Costello Susie , Kanyi Teresia , Dalling Matthew
Published: August 2019

This article describes a United Nations Children’s Fund project to develop a child protection curriculum in social work schools in Palestine conducted over 2016, 2017 and 2018. The curriculum was delivered in the West Bank and Gaza, as well as to a delegation from Palestine in Melbourne. The article discusses the challenges and highlights in introducing a rights and strength-based, child-focused, family-inclusive, and trauma-informed child protection curriculum in the context of occupation, poverty and patriarchy. It emphasises the need for critical reflection for foreign educators in relation to culture, gender, human rights and anti-oppressive practices when teaching in the Middle East and other collective cultures. The key outcomes were new collaborations between Palestinian academics from Gaza and the West Bank, as well as their preference for family group conferencing over traditional Western case management models of child protection to promote peaceful, inclusive societies.
‘Show us you care!’ The gendered psycho-politics of emotion and women as political leaders
Authors: Yates Candida
Published: August 2019

This article deploys a new psycho-political approach to examine the relationship between female political leadership and the emotionalisation of political culture by focusing on the case study of the media coverage of the former UK Prime Minister Theresa May. The article argues that the emotional turn in political culture is a gendered phenomenon because it reinforces deeper fears and fantasies about irrational femininity and the inherent instability of female political leadership and women in the public sphere.
Expressing suchness: On the integration of writing into a dance practice
Authors: Collard-Stokes Gemma
Published: August 2019

This article details the unique pairing of dance and writing, the likes of which are often considered two very different beasts. It examines how approaches to movement improvisation have been used to form and inform innovative methods of entering into the act of writing from the experience
of dance. The argument authenticates the current renewed appreciation for the possibilities of writing to enable further creative critical engagement. Consequently, the meeting of creativity and criticality is one in which the dancer playfully explores and examines the suchness of one’s
dancing. Suchness is therefore understood as the unique sum of qualities experienced by the dancer – the point at which clarity and closeness facilitate connection through the images, feelings and sensations evoked by dance. In summary, the article outlines the relationship between dance
and writing, before exploring the methods used to facilitate a dancer’s assimilation and validation of what happens for them when they dance.
Book Reviews
Authors: Naccarato Teoma , Stamp Kathryn
Published: August 2019

Radio Strainer: Part Two of the Kinesthetic Archive, Alys Longley (2015) Winchester: Winchester University Press, ISBN 978-1-90611-316-2, p/bk, £20.00The Oxford Handbook of Dance and Wellbeing, Vicky Karkou, Sue Oliver and Sophia Lycouris (eds) (2017) Oxford: Oxford University
Press, £115, 968 pp., ISBN 978-0-19994-929-8, h/bk; epub ISBN: 9780190655112
Colours on the surface of my body in motion: The relationship between synaesthesia and dance improvisation
Authors: Scheubeck Stephanie
Published: August 2019

In synaesthesia, the stimulation of one sense or cognitive concept simultaneously and involuntarily produces a sensation in a second sense or cognitive experience. while synaesthesia has been investigated from neuroscience and psychology to social sciences and the arts, the relationship
between synaesthesia and dance is largely un-researched. This article provides insight into my practice-led research project on the relationship between synaesthesia and dance improvisation, informed by somatic practice. It demonstrates the interrelation of synaesthesia and dance improvisation
when performed by a synaesthete, and discusses the role of attention in this context as well as explorations of the relationship between synaesthesia, somatic practice and dance improvisation by synaesthetes and non-synaesthetes. In conclusion it is suggested that research into synaesthesia
through dance and somatic practice can contribute to an integral understanding of this highly quantitatively investigated phenomenon.
‘[...] wind in my hair, I feel a part of everywhere [...]’: Creating dance for young audiences narrates emplacement
Authors: Akinleye Adesola
Published: August 2019

This article is a reflection from a moment during the tour of my performance work for young audiences – Found. I explore how the meaningfulness shared in the moments dancing together captures much broader narratives about the transformative connections of Being-in-Place: emplacement.
I respond to Sarah Pink’s call to explore bodily experiences through emplacement. Therefore, I use emplacement as a lens to theorize experiences during the practical performance work of Found, beyond the visual aesthetic of seeing live dance. This articulating and valuing the significance
of where Self begins, or ends or is continuous in environment shares somatic inquiry with colleagues in architecture, social sciences and geography. I suggest ramifications on how dance offers corporeal dialogue that can empower children to take part in, and become aware of, their own presence
in the co-created reality of Place.
Chat to Mi Back: Meditation on body archive
Authors: Webster Carol Marie
Published: August 2019

This article addresses the concept Body as Archive in the context of contemporary Jamaica, a nation simultaneously grounded in Christian Religiosity and rooted in African Cosmology. Body as Archive is identified here as an understanding of the body that recognizes bodily artefacts as
stored in individual and collective bodies for future generations to excavate, critically interrogate, re-craft and/or restore and deploy in the fashioning of present-day individual and community identities, life possibilities and future world imaginings. At its core Body as Archive is the
work of the imagination to manifest the body as both archive and artefact, both a space for the collection and recording of historical memory and remembrance and itself an expression of memory and re-membrance. In contemporary Jamaica Body as Archive encompasses notions of beauty, the role
of dance, and the significance of performance around and about the Jamaican female body. Embedded in this current exploration is an interrogation of the ways in which the bio-political imagination of past generations inform the excavation and deployment of bodily artefacts in the present.
The dancer as documenter: An emergent dancer-led approach to choreographic documentation
Authors: Parker Sandra
Published: August 2019

Realigning the interrelationship between documentation, choreography and the lived moment of performance, this article asks how choreographic documentation practices can be reimagined to articulate deeper layers of embodied knowledge beyond a focus on movement patterns or gestures.
Entrusting the dancer to drive the process, accentuating their expertise in perceiving and analysing bodily sensation, the article proposes a series of experimental documentation methods. These include the use of verbal language, the breaking down of choreographic continuity and linear phrasing,
and ‘enactive’ filming, with repetition as an exploratory tool. Developed through practice, these methods consider the use of available technologies (laptops, smartphones, etc.), informed by theories of enactive perception. By relieving the tension between the immediacy of performance
and choreography as a framework of previously defined choices and limits, the article focuses on the dancer as the primary asset in the documentation process, advocating their agency in articulating interior knowledge and lived bodily experience in documented forms.
Fascial embodiment in movement, training and dance education: Insights from a somatic workshop
Authors: Stollbrock Trujillo Haike Irina Amelia
Published: August 2019

The purpose of this article is to describe how students exploring fascia through somatics experience its embodiment. This is done by discussing their written impressions of the somatic workshop: ‘Fascia & movement’, which I taught in dance institutions in Bogotá
and Barcelona as of 2015. This narrative material will serve to look for further connections between fascia research and the dance education field. The article begins by reviewing some core findings of fascia research and the Anatomy Trains1 model. It discusses the concepts of somatic movement
(SM), embodiment and the place of writing within classes, offers a specific class example and describes the methodology and limits of the workshop design and the narrative approach. Then, I compare the main qualities and functions of the fascia with the subjective experiences of fascial embodiment.
The most relevant experience found is a sensation of wholeness that comes from within, while a new awareness of internal connections and adaptability takes place. Finally, I will present some contributions, tactics and precautions of integrating fascial understanding into dance, movement education
and self-development.
Body inking: butoh: (a poetic narrative): ... artist pages
Authors: Preece Bronwyn
Published: August 2019

The writing becomes a limbed extension – a dance – inked on shore and paper by a body moving in these artist pages. The author poetically captures the process of engaging in the 22nd annual Kokoro Dance Theatre Society’s Wreck Beach Butoh Intensive: a nine-day in-studio
period, followed by three outdoor performances: on the shores and in the waters of Vancouver, Canada’s Pacific Ocean. Preece captures the days in a poem, synthesizing felt experience with elements of the daily choreography and context, offering palpable, personal and sensual tellings
of one woman moving through process, practice and performance. Although specific, the poems remain accessible – interpretable and relatable to the reader – as fresh offerings, as movements themselves.
Exploring multiple identities: An embodied perspective on academic development and higher education research
Authors: Leigh Jennifer
Published: August 2019

In this article I discuss how my background as a somatic movement therapist and educator has informed my identity and current work as a higher education (HE) researcher and academic developer, or teacher of HE. I explore what it means to come from a non-traditional home discipline,
and to work in a non-unified field within academia. How does it impact on academic credibility, and the practical choices of methodology and dissemination? What might a new, less traditional home discipline bring to HE research, and what problems might arise for a researcher wanting to draw
on less known or regarded methods, practices or theories of research? Within somatic movement and education the ethos of embodiment, that is an awareness of the importance of the body, underlies all theory and practice. Elements of this ethos can also be found across many disciplines within
academia. HE is a non-unified field that has been described as atheoretical or without an overarching theoretical base. It attracts researchers from a wide variety of disciplinary backgrounds, and yet draws strongly on social science and hard science descriptions of rigour, validity and what
is considered knowledge and research. In this article I take a reflective and embodied approach to consider how this impacts on issues of credibility working in HE, drawing on conversations with other HE researchers and academic developers, and the consequences and tensions that result.
Effects of a standardized 40% ellagic acid pomegranate (Punica granatum L.) extract on seminiferous tubule histopathology, diameter, and epithelium thickness in albino Wistar rats after heat exposure
Authors: Utomo Budi , Daningtia Nurfitri Rahmah , Yuliani Gandul Atik , Yuniarti Wiwik Misaco
Published: August 2019

Background and Aim: It has long been known that the spermatogenic tissue is very sensitive to temperatures higher than its physiologic temperature and causing cessation of activity and resulting in sterility. This study investigated the effect of a standardized 40% ellagic acid extract of pomegranate on the histopathology, diameter, and epithelial thickness of seminiferous tubules in albino rats exposed to heat.

Materials and Methods: Twenty-five male albino Wistar rats were randomized at 7-8 months of age to five treatment groups. Group C was not treated; Group T0 was treated with 0.5% of Na carboxymethyl cellulose (CMC) 2 ml/day and exposed to heat. T1, T2, and T3 were treated with 75, 150, and 300 mg/kg/day of a standardized 40% ellagic acid extract of pomegranate (Punica granatum L.), respectively. The animals were orally administered Na CMC or pomegranate extract and were exposed to sunlight for 15 min at 40°C-42°C for 14 days. The animals were sacrificed on day 15 and the testes were removed for histological evaluation and measurement of seminiferous tubule diameter and epithelium thickness.

Results: The diameter of seminiferous tubules from rats exposed to heat and treated with 300 mg/kg/day pomegranate extract was larger and the epithelia thicker than those in the other groups (p= <0.05). The protective effects of the standardized 40% ellagic acid extract may have been mediated by its antioxidant activity.

Conclusion: Compared with controls, administration of 300 mg/kg/day of a standardized 40% ellagic acid extract of P. granatum L. for 14 days increased seminiferous tubule diameter and epithelium thickness in albino Wistar rats exposed to heat.

Keywords: diameter, epithelium thickness, heat, pomegranate extract, seminiferous tubule.
Evaluation of hepatobiliary ultrasound scores in healthy dogs and dogs with liver diseases
Authors: Assawarachan Sathidpak Nantasanti , Chuchalermporn Piyathip , Maneesaay Phudit , Thengchaisri Naris
Published: August 2019

Background and Aim: Ultrasonography is the first-line method for examining the canine liver. Hepatic ultrasound scoring systems are widely described in human medicine, yet there is no information on the use of semi-quantitative ultrasound scoring systems in canine liver diseases. This study aimed to evaluate the hepatobiliary ultrasound scores between physically healthy dogs and dogs with primary liver diseases confirmed by clinical, biochemical, and histological parameters. We also evaluated the putative correlations between ultrasound scores and ALT or ALP levels. Moreover, the severity of ultrasound scoring and fold changes in liver enzymes was also evaluated. Materials and Methods: A cross-sectional study design was conducted to compare the results of the six different parameters (liver surface, echogenicity of parenchyma, nodularity of parenchyma, gallbladder wall thickness, amount of gall sludge, and visibility of bile duct) of ultrasound scores between dogs with and without liver disease. Results: Our results showed that 17.4%, 88.2%, and 100% of dogs with liver diseases were identified according to the ultrasound severity classified as mild (total score 0-2), moderate (total score 3-5), and severe (total score 6-12). Approximately 30% of patients with chronic hepatitis, the most common canine liver disease, presented with normal or mild ultrasound score category, whereas most of the patients with vacuolar hepatopathy and steroid-induced hepatopathy due to secondary reactive changes had moderate-to-severe ultrasound score category. There were 75% of patients with tumor and 80% of patients with hepatic fibrosis that were identified with severe ultrasound score category. Dogs with moderate-to-severe ultrasound scores had significant liver enzyme elevation (both alanine aminotransferase [ALT] and alkaline phosphatase [ALP]) compared to those of dogs with mild ultrasound scores. Ultrasound score was moderately associated with ALT and highly associated with ALP levels (p=0.553 and p=0.730, respectively). Conclusion: Our semi-quantitative, simplified ultrasonographic scoring system may have potential to be used as a screening tool to detect some groups of liver diseases. Keywords: diagnosis, dogs, hepatic disease, ultrasound score.
Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase: Finding Aspartate Aminotransferase a Better Mortality Predictor for All-Cause and Liver-Related than Alanine Aminotransferase
Authors: Xie Kunlin , Chen Chien-Hua , Tsai Shan-Pou , Lu Po-Jung , Wu Hong , Zeng Yong , Ye Yuanqing , Tu Huakang , Wen Christopher , Huang Maosheng , Zhang Yajie , Lee Jun-Han , Tsai Min-Kuang , Wen Chi-Pang , Wu Xifeng
Published: August 2019

OBJECTIVES:

Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are 2 commonly ordered liver function tests, and ALT has long been considered more liver-specific than AST. Between the 2, the one which is better in predicting liver or non–liver-related mortality remains unsettled.

METHODS:

The cohort, 416,122 adults, came from a self-paying comprehensive health surveillance program during 1994–2008 and was followed up till 2008. Mortality came from National Death Index, with 10,412 deaths identified. Hazard ratios (HRs), computed by Cox model, and life expectancy, by life table method, were presented for 5 levels of AST and ALT with elevated AST or ALT defined as ≥40 IU/L. Liver disease included liver cancer and other liver conditions.

RESULTS:

There were 3 times more elevated ALT (15.4%) than AST (5.7%). However, those with elevated AST had higher mortality for all-cause (HR = 2.44), for liver disease (HR = 27.2), and for liver cancer (HR = 47.6) than its ALT counterparts (HR = 1.69, 10.8, and 20.2, respectively). Elevated AST also lost more years of life expectancy (10.2) than those lost by ALT (5.2) and larger than most common risks. Elevated AST had increased mortality from all cancers (HR = 3.57), stroke (HR = 1.36), respiratory diseases (HR = 1.34), and injuries (HR = 1.82), other than just liver disease. All-cause mortality remained significantly increased, when high risk groups were excluded, such as frequent drinkers, hepatitis carriers, those died from nonmedical conditions, those died in the first 3 years, or advanced fibrosis index based on 4 factors or aspartate transaminase-to-platelet ratio index. Results were consistent between those returned for second visits and those analyzed in initial visits.

DISCUSSION:

Those with elevated AST (≥40 IU/L) had life expectancy cut short by 10.2 years, doubled the number of years lost with elevated ALT. For all-cause and for liver-related mortality, AST was an important predictor, better than ALT.