bluuebunny/crossref_metadata_2025 huggingface dataset:
Validación de un instrumento para evaluar la gestión integral de la seguridad en laboratorios académicos
Authors: Álvarez-Chávez Clara Rosalía , García-Rendón Angélica , Marín-Ramírez Luz S. , Flores-Soto Alma Angelina , Esquer-Peralta Javier
Published: January 2024

La seguridad en el laboratorio de ciencias es un área de importancia debido a los peligros a los que se puede encontrar expuesta la comunidad escolar usuaria. El instrumento original IGSSA (indicador de gestión, salud, seguridad y ambiente) fue propuesto para evaluar la gestión de la salud, seguridad, protección civil y ambiente en el laboratorio de ciencias de nivel medio superior. IGSSA está compuesto de un cuestionario (111 ítems) clasificados en 4 subindicadores. El objetivo del presente estudio fue validar el instrumento IGSSA para ser utilizado por los docentes en inspecciones de cumplimiento regulatorio en laboratorios académicos de ciencias. La metodología de validación del cuestionario incluyó grupos focales con representantes de entidades regulatorias y entrevistas cognitivas con docentes de laboratorio. El instrumento final IGSSA-LAB v1 consiste en un indicador compuesto que agrupa 85 ítems clasificados en 7 subindicadores. El instrumento tiene un enfoque participativo al proponer al docente como inspector de laboratorio, en apoyo al cumplimiento regulatorio, a la vez que fomenta la capacitación y el fortalecimiento de la cultura de seguridad y protección al ambiente en instituciones educativas de nivel medio superior.
Los puntos cuánticos y el premio Nobel de Química 2023
Authors: Muñoz Cartagena Eduardo
Published: January 2024

El premio Nobel 2023 en el área de química, fue concedido a 3 investigadores: Alexei Ekimov, Luis Brus y Moungi Bawendi, por sus aportes al descubrimiento, caracterización y control de la producción de los puntos cuánticos. Los puntos cuánticos son nanoestructuras semiconductoras que exhiben propiedades cuánticas, i. e., propiedades dependientes del tamaño. De acuerdo a estos aportes al conocimiento, es que desde mediados de los años 90’s estas nanopartículas tienen diversas aplicaciones tecnológicas, tales como en la industria de la electrónica y la óptica, así como en la medicina, producción de sustancias, sensores, conversión de energía, entre otras. Este manuscrito busca dar una mirada general a las propiedades químicas y físicas de los puntos cuánticos, a los aportes de los investigadores galardonados en este campo, y a una experiencia propia en la utilización de estas partículas con fines de sensor de sustancias reactivas.
Email Management Platform
Authors: Kachole Abhinav
Published: January 2024

Abstract: This research project endeavors to enhance the email experience for users across the globe. The overarching goal is to create an innovative email platform that accommodates speakers of any language. The project aims to simplify email management, facilitate text translation across languages, incorporate text-to-speech and speech-to-text functionalities, bolster security against threats and malware, automate mail classification and grouping, and implement advanced spam filtering. The study explores the synergy of various technologies to improve the user interface and overall functionality, contributing valuable insights to the discourse on the intersection of technology and global connectivity. This research not only seeks to make emails more efficient but also aims to play a role in shaping a more user-centric and inclusive digital communication landscape. In the course of this research, the focus extends beyond the technical aspects to delve into the ways in which individuals from diverse backgrounds engage with email. By understanding the unique needs and preferences of users worldwide, the project aims to create an email platform that transcends linguistic and cultural barriers. This research contributes not only to the refinement of email technology but also to the broader conversation about the societal impact of technology in fostering global connections. The study promises an enlightening exploration into the future of email and its potential to foster a more connected and harmonious digital world.
Mathematical Modelling and Simulating Applications
Authors: Kumar Prakash
Published: January 2024

Abstract: This paper reveals the importance of mathematical modelling, its growing role and its applications. It is a myth that modelling projects progress easily from working throughto utilizing, this is scarcely ever the situation. In computer science, the use of modelling and simulating a computer is utilized to fabricate a mathematical model which contains key boundaries of the actual model. Thus, the study aims to give a basic idea of mathematical modelling, its uses, and its role in recent scenarios.
Spor Bilimleri Fakültesi Öğrencilerinin Stresle Başa Çıkma Tarzları ile Yaşam Doyumları Arasındaki ilişkinin İncelenmesi
Authors: KARABULUT Ebru Olcay
Published: January 2024

Bu çalışmanın amacı spor bilimleri fakültesi öğrencilerinin stresle baş etme tarzları ile yaşam doyumları arasındaki ilişkinin incelenmesidir. Araştırmada nicel bir araştırma yöntemi olan ilişkisel tarama modeli kullanımı tercih edilmiştir. Araştırmanın çalışma grubunun evrenini, Gazi Üniversitesi Beden Eğitimi ve Spor Yüksekokulu’nda öğrenim gören üniversite öğrencileri, örmeklemini ise tasadüfi olarak seçilen ve araştırmaya gönüllü katılan 236 kadın, 224 erkek toplam 460 öğrenci oluşturmaktadır. Verilerin toplanmasında Şahin ve Durak (1995) tarafından uyarlanan “Stresle Başa Çıkma Tarzları Ölçeği (SBTÖ)” ve Dağlı ve Baysal (2016) tarafından uyarlanan “Yaşam Doyumu Ölçeği (YDÖ)” kullanılmıştır. Araştırmanın verilerinin homojen dağılım sergiledikleri tespit edildikten sonra parametrik analizlerden t-Testi ve Anova testi kullanılmıştır. Analizlerde anlamlılık düzeyi 0.05 olarak belirlenmiştir. Öğrencilerin yaşam doyumları ve Stresle baş etme tarzları arasındaki ilişki ise Pearson Korelasyon Analizi ile değerlendirilmiştir. Sonuç olarak, kadınların stresle baş etmede iyimser yaklaşım tercih ettikleri, yaşın stresle başa çıkma tarzlarına ve yaşam doyumuna etkisinin olmadığı, antrenörlük bölümü öğrencinin kendine güvenli baş etme tarzlarını benimsediği, rekreasyon öğrencilerinin ise işlevsel olmayan boyun eğici ve çaresiz yaklaşımı tercih ettiği bulunmuştur. Sonuçlarda ayrıca, 4. Sınıfların kendine güvenli yaklaşım tercih ettiği, 3. Sınıfların ise yaşam doyumlarının yüksek olduğu, gelir seviyesinin yüksekliği işlevsel baş etme tarzlarını benimsemeyi etkilediği ve yaşam doyumunu olumlu etkilediği, düşüklüğünde ise işlevsel olmayan tarzlar benimsemeyi etkilediği tespit edilmiştir
The effect of Arbuscular Mycorrhizal Fungi (AMF) on agronomic characteristics of clove seedlings of superior local variety of East Halmahera
Authors: Lala Fredy , Cahyaningrum Hermawati , Hidayat Yayat , Suwitono Bayu
Published: January 2024

Cloves (Syzygium aromaticum L.) have taproots but during the dry season the plants suffer from drought. Increasing the surface area of plant roots in the nursery is very important to produce clove plants with roots that have a high absorption of water and nutrients from the soil. The aim of this study was to determine the effect of arbuscular mycorrhizal fungi (AMF) on the growth of clove seedlings in the nursery and their nursery business. The research was conducted at a clove nursery in Telaga Jaya Village, South Wasile District, East Halmahera Regency, North Maluku from May to October 2020. The study used a Completely Randomized Block Design consisting of 4 treatments and three replications. The treatments were AMF doses: 0 g, 25 g, 50 g, and 75 g on each polybag. The results showed that the application of AMF increased plant height, number of branches, number of leaves, stem diameter, root length, and fresh weight of roots. East Halmahera clove nursery business had higher profits when using AMF than without AMF application.
Bir Başlangıç Hikâyesi: Eğirdir Su Ürünleri Fakültesi’nin 41. Yılı
Authors: Kubilay Ayşegül
Published: January 2024

Çalışmada; ülkemizin balıkçılık konusunda gelişmiş ülkeler seviyesine ulaşabilmesi için lisans düzeyinde eğitim ve öğretim yapan Su Ürünleri Fakültelerinin kurulmasının ilk aşamaları ve 20 Temmuz 1982 tarih, 41 Sayılı Kanun Hükmünde Kararname ile kurulan 6 adet Su Ürünleri Yüksekokulu arasında yer alan, Cumhuriyetimizin kuruluşunun 100. Yılını kutladığımız bu günlerde, 41. Kuruluş yıldönümünü kutlayan Eğirdir Su Ürünleri Fakültesi’nin kuruluş hikayesi anlatılmıştır.
Adult Acne in Middle-age: Effects on Mental Health in General Population of the Northern Finland Birth Cohort 1966
Authors: Leskelä Marjukka , Jokelainen Jari , Huilaja Laura , Sinikumpu Suvi-Päivikki
Published: January 2024

The impact of adult acne on patients’ mental health has not been widely studied, and most studies have been conducted within specific patient populations. The current study examines the association between adult acne and psychological symptoms in the Northern Finland Birth Cohort 1966 (NFBC1966) (n = 1,907). The cohort members attended a health study at the age of 46 years, which comprised a whole-body examination performed by dermatologists to identify acne, and answering the Beck Depression Inventory II (BDI-II), Athens Insomnia Scale (AIS), Generalized Anxiety Disorder (GAD-7), State-Trait Anxiety Inventory (STAI) and 15-dimensional measure of health-related quality of life (15D HRQoL) questionnaires. The prevalence of adult acne was 7.9% (n = 150) with no statistical differences between the sexes. Cases with acne presented more (18.9%) depressive symptoms (BDI-II > 14 points) compared with those without acne (9.7%) (p < 0.001). In adjusted logistic regression analyses, those with acne had a 2-fold risk (odds ratio (OR) 2.08, 95% confidence interval (95% CI) 1.23–3.38) of having depressive symptoms compared with controls. In conclusion, when treating adult acne patients, it is important to recognize the increased risk of mental health symptoms.
Mutualismo en Chile, 1848-1990: seguridad social, movimiento sociopolítico y espacio de sociabilidad de la clase trabajadora
Authors:   Universidad de Concepción, Venegas Espinoza Fernando
Published: January 2024

En el contexto actual de búsqueda de alternativas al sistema de pensiones en Chile, este estudio se enfoca en la trayectoria histórica del mutualismo mediante una revisión exhaustiva de fuentes originales. La investigación propone una interpretación centrada en factores culturales, sociales y económicos. Contrariamente a lo sostenido por la historiografía, se plantea que el mutualismo no inició su crisis terminal tras la promulgación de la ley del Seguro Obrero en 1924. Si bien la Gran Depresión de 1929 afectó a estas organizaciones, hay que contextualizarla como parte de un escenario de crisis generalizada desde principios del siglo XX. Esto permitió que las organizaciones mutualistas se recuperaran y volvieran a expandirse en las décadas siguientes, hasta la llegada de los años 1970. No obstante, las crisis continuaron sucediéndose y se profundizaron debido a varios factores. Entre ellos se destacan las atribuciones otorgadas por el Estado a la Confederación Mutualista de Chile en 1963, así como el impacto de las medidas represivas y las transformaciones culturales asociadas al modelo económico implementado durante la dictadura cívico-militar. La investigación se basa en la documentación inédita de la Confederación Mutualista de Chile, lo que enriquece considerablemente nuestra comprensión del mutualismo en el país y permite arrojar luz sobre su evolución histórica y sus desafíos actuales.
De cuasi delito a delito culposo: tipificación del incendio involuntario en el derecho hispánico (Siglos XI-XIX)
Authors:   Universidad Bernardo O'Higgins, De Nardi Loris
Published: January 2024

Durante el siglo XVIII se empezaron a definir los parámetros de la moderna codificación penal y del sistema judicial y penológico. El replanteamiento global de la economía, la organización social, las formas de convivencia y, en general, las diversas facetas de la vida del hombre, propio de esta centuria, no podían no abarcar la legislación criminal. Dicha rama normativa era una herramienta clave para reafirmar la autoridad del Estado, proteger el orden social que él mismo había establecido, disciplinar socialmente a los individuos como también sus prácticas de comportamientos. Al mismo tiempo, las élites ilustradas tenían muy claro que el replanteamiento de la normativa criminal habría favorecido el amplio proceso de regulación e instrucción social, que, por afectar todos los ámbitos de la vida, habría permitido contrarrestar todas aquellas prácticas y costumbres que se contraponían a su discurso y visión sistémica. Así lo demuestra la tipificación como delito penal del incendio involuntario: si durante la época medieval y moderna el incendio ocasionado por imprudencia o negligencia, es decir, sin dolo, se consideró únicamente un cuasidelito civil, y como tal obligaba el responsable únicamente a la indemnización de los daños, con la codificación penal decimonónica terminó por ser elevado a delito penal. Este artículo se propone reconstruir las etapas principales de esta transición, y explicar los motivos sociales y culturales que la impulsaron.
Mapas corporales y genealogías de vida. Metodologías para contar la historia cotidiana de mujeres afrobolivianas de Tocaña
Authors:   Universidad Mayor San Andrés, Oros Rodríguez Varinia
Published: January 2024

En el proyecto «Mapas de Vida: Genealogías e Historias de Mujeres de Tocaña», se utilizan las metodologías de Mapas Corporales y Genealogías de Vida para visibilizar y recuperar la historia y la memoria de las mujeres afrobolivianas en la comunidad de Tocaña. A través de los talleres que se llevaron a cabo, se promovió un diálogo abierto y participativo entre el equipo del proyecto y las mujeres de la comunidad. Mediante los mapas corporales, las participantes plasmaron simbólicamente sus experiencias, emociones y relaciones con sus cuerpos, explorando temas como la menstruación, la identidad étnica y los vínculos afectivos. Por otro lado, las genealogías de vida permitieron activar la memoria colectiva a través de la narración y el intercambio de historias de vida, explorando temas como la educación, las relaciones familiares y las experiencias cotidianas. Estas metodologías feministas brindaron herramientas para empoderar a las mujeres, promover la reflexión sobre sus propias experiencias y fortalecer la solidaridad y la comunión entre ellas. El proyecto culminó con una exposición que presentó los resultados de estas metodologías, utilizando escritos, fotografías y material audiovisual para compartir y visibilizar las voces y las historias de las mujeres afrobolivianas.
Infanticidios, control social y violencia patriarcal. Reflexiones en clave de género (provincia de Buenos Aires, Argentina, 1886-1921)
Authors:   Universidad Nacional de La Plata, Calandria Sol
Published: January 2024

Esta investigación analiza el infanticidio en clave de género en la legislación y en la praxis penal, haciendo foco en las formas que adquiere la violencia patriarcal y la honra femenina en el control social de las mujeres en la provincia de Buenos Aires, Argentina, entre 1886 y 1921. La honra fue un dispositivo del poder y dominación patriarcal; a través de los debates en torno a la honra femenina se pueden observar las prácticas e ideas que operaron en la capilaridad del ejercicio del poder, reproduciendo desigualdades estructurales. El trabajo utiliza fuentes penitenciarias y judiciales de los delitos de infanticidio cometidos por mujeres, para analizar: 1) el proceso sociohistórico a través del cual se «maternaliza» el infanticidio, es decir, se delimita la figura jurídica como un delito propio de las mujeres, que derivó en la persecución unívoca de las madres solteras; 2) el control social como expresión de las violencias y desigualdades de género, ya que se ejerció con una doble moral; 3) las tensiones en torno a la honra femenina que se dan en los juicios, y que reproducen los prejuicios y mandatos sociales sobre las sexualidades femeninas y la moralidad.
Void and Falcate-Signet Ring Stromal Tumour-Ovary
Authors: Bajaj Anubha
Published: January 2024

Signet ring stromal tumour represents as an exceptionally discerned, benign, primary ovarian neoplasm wherein the ovarian stroma is pervaded with signet ring cells. Additionally designated as signet ring stromal cell tumour or signet ring stromal tumour, tumour cells are permeated with cytoplasmic vacuoles, thereby configuring signet ring cells. As the ovarian stromal neoplasm is constituted of variable proportion of signet ring cells and spindle shaped cells, nevertheless, vacuolated signet ring cells are devoid of lipid, mucin or glycogen.
Compilation and Embodiment-Leydig Cell Tumour Testis
Authors: Bajaj Anubha
Published: January 2024

Leydig cell tumour is a commonly discerned sex cord stromal tumour arising within testes. Previously designated as interstitial cell tumour, the cellular tumefaction recapitulates non neoplastic Leydig cells. Nearly < 10% neoplasms appear overtly malignant. Neoplasm represents with diffuse or nodular pattern of tumour evolution. Constituent polygonal cells are pervaded with abundant, granular, eosinophilic cytoplasm, uniform spherical nuclei and prominent centric nucleoli. Intracytoplasmic Reinke’s crystals may be discerned.
Validation of Patient-Oriented Risk Assessment Tool in Indian Patients with Obesity: Results from the Large-Scale Evaluation of the Novel Concept Tool
Authors: Bhasker Aparna G.
Published: January 2024

Aim and Background: The global upsurge of the obesity epidemic has led to an urgent need for measurement tools for obesity research and practice. Patient-oriented tools are important for determining the effectiveness of management and treatment of obesity. The current study objective was to evaluate the clinical validity of an obesity risk assessment tool in a large sample of patients suffering from obesity in India. Methods: This study was conducted between August 2021-August 2022 in which a user-friendly, patient-oriented obesity risk assessment questionnaire was digitally administered to patients suffering from obesity. Data was analysed using a multivariate ordered logistic regression model (OLM), and discriminant analysis was performed to validate the model’s predictability. Results: The questionnaire was completed by 1046 patients includes 639 (61.09%) female and 407 (38.91%) male participants. The mean age of patients was 41.29±12.4 years (age range: 15–97 years), and the mean BMI was 46.75±19.41 kg/m2 . The ordered regression model predicted bariatric surgery for 66.63% of patients, diet and exercise for 6.9%, and pharmacotherapy for 4.6% of patients. Overall, our findings suggest that the model had an accuracy of 78%, providing evidence for the validity of the tool and suggesting next action steps to be taken by patient. Conclusion: The obesity risk assessment tool has potential as a patient-oriented tool because of its ease of use for the assessment and providing guidance to seek next steps for appropriate management of obesity. It can be applied to both sexes at all ages and may provide the simplest and most valid risk assessment tool to enable patients to move from awareness to action.
Spatial Analysis of the Hepatitis C Epidemic in Bengbu, China between 2013 and 2022: A Retrospective Study
Authors: Han Xie
Published: January 2024

This study aimed to reveal the epidemiological trends and spatial distributions of hepatitis C, in Bengbu, China during 2013- 2022, and provide a scientific reference for HCV prevention, intervention, and treatment. 3034 HCV cases were identified (2013-2022). The number of HCV cases increased from 28 in 2013 to 832 in 2018 and decreased from 832 in 2018 to 431 in 2022. Among the HCV cases recorded during study period, 25.54% were 45–54 years old, 60.31% were farmers, and 52.04% were male. Spatial analysis showed that the cases were concentrated in eastern towns. Spatial-temporal clustering was concentrated in the center of Bengbu, such as Lilou, Hongye, Huangzhuang and Jiefang. Spatial regression analysis showed that per capita gross domestic product and sex ratio had statistically significant positive correlations with HCV infection. Frontline health workers can provide targeted health education and strengthen interventions for the target population.
Interest of a Three Phase Bone Scintigraphy Protocol in the Diagnosis and Management of Osteoarticular Infections in Children. About 31 Cases
Authors: El Mselmi Sanae
Published: January 2024

Introduction: Osteoarticular infection is a particularly common pathology in children. The diagnosis is sometimes difficult especially in front of a poor symptomatology and a little disturbed biological assessment. The aim of this work is to assess the contribution of bone scintigraphy in the diagnosis of osteoarticular infections in children. Patients and Method: This is a retrospective study spread out between December 2012 and February 2019, involving children referred to the nuclear medicine department of Hassan II University Hospital Center of Fez for suspected osteoarticular infection. All the children benefited from a bone scan with a triple phase acquisition followed by a study of the entire bone skeleton, after an IV injection of 10 MBq /Kg of MDP-Tc99m. Results: We selected 31 children. The average age was 9.43 years old with a male predominance. The clinical signs mainly found in our patients were fever, bone pain and functional impairment of the affected limb. The main location was the lower limb (74.2%). Bone scan was positive in 70.9% of patients, including 9 cases of septic arthritis, 7 cases of osteomyelitis, 4 cases of sacroiliitis and one case of lumbar spondylodiscitis. Conclusions: Three-phases bone scintigraphy protocole with MDP-Tc99m completed with a whole body bone scan should remain the examination of choice in osteoarticular infections in children. This exam makes it possible to retain an accurate diagnosis in an early stage of OAI while the other medical imaging modalities exams being negative. Thus allowing to prevent severe complications with an affordable financial cost and an acceptable irradiation rate.
Cystic Adenoid Carcinomas of the Parotid: About 3 Cases and Review of Literature
Authors: F Allouch
Published: January 2024

Adenoids cystic carcinomas (CAKs) represent 2-4% of parotid tumors and 12% of malignant tumors. These are slow growing tumors that are characterized by their ability to infiltrate the nerve sheaths. We collected three cases of CAK of the parotid gland diagnosed and treated between 2012 and 2018. These were 03 women who consulted in front of the appearance of a swelling of the parotid compartment associated with a facial paralysis in a case. The lymph node areas were free. All patients underwent exploration including ultrasound, CT in one case, and MRI in one patient. Treatment consisted of a total parotidectomy associated with lymph node dissection in all cases and additional radiotherapy. The evolution was favorable in two cases. The adenoid cystic carcinoma of the parotid is a rare tumor, characterized by a very slow evolution, a local aggressiveness, a strongly recurrent character locally and a high metastatic capacity at a distance.
Study of Radiation Doses during Cerebral, Thoracic and AbdominalPelvic Ct Scans in Adults at the Teaching University Hospital of Cotonou (Cnhu-Hkm)
Authors: Yekpe A Patricia
Published: January 2024

Introduction: Knowledge of CT scan dose delivery is a legal obligation and an imperative of good practice. In Africa, radiation protection is a concern due to the non-compliance with established laws and regulations. The objective of this study was to study the radiation doses emitted by cerebral, thoracic and abdominal-pelvic computed tomography at the CNHU-HKM in Cotonou. Methods: This was a cross-sectional descriptive study with prospective collection. It took place from August 2019 to January 2020, over a period of six (06) months. An exhaustive census of scans exploring the skull, and/or trunk was made. The variables studied were the clinical data, the status of the examination prescriber, the type of examination and the dosimetric data of the examinations. Results: During our study period, 2788 CT scans were performed, 1150 were retained including 1046 (91.0%) in adults. CT scans were performed in overweight patients (38.6%). The majority of the performed exams were justified regardless of floor explored. The 75th percentile values of CTDI and LDP were not compliant in 59.7% and 58.4% of cases, respectively. The average effective dose for a brain scan is 3.2 mSv. Doses variation was observed according to body mass index. Conclusion: At the end of this study, the majority of the exams carried out were justified. The 75th percentile values of the dosimetric indices (CTDI, LDP) were higher than the diagnostic reference levels established by the Nuclear Safety Authority in 2019.
Preliminary Study on Human Dose of X and Γ Flaw Detection Accident Based on FLUKA
Authors: Z Zhang
Published: January 2024

In this work, a Chinese reference human voxel model was established in FLUKA software to simulate the energy deposition, absorbed dose and its spatial distribution. Then the energy deposition, absorbed dose and its spatial distribution were got with different energy photons directly irradiating the human chest under radiation accident in industrial flaw detection. The results showed that organs with high energy deposition were lung, heart, muscle, soft tissue, liver and skin, and the absorbed dose of lung was the highest. The simulation of radiation accident in industrial flaw detection based on the Chinese reference human body model was feasible in FLUKA software. The absorbed dose results of human organs have reference value and significance for the evaluation of similar radiation accidents.
Effects of Some Processing Methods on Organoleptic Properties and Proximate Composition of Sarotherodon melanotheron
Authors: OMG Abu
Published: January 2024

The effects of different preservation methods (oven dried, fried and smoked) on the nutritional composition and organoleptic properties in black jaw tilapia, Sarotherodon melanotheron were carried out. All processing methods revealed significant difference (p<0.05) in the various nutritional composition. Among the methods of preservation, smoked fish had the highest protein (64.66%), closely followed by dried fish. Comparative assessment on organoleptic qualities of oven dried, smoked and fried fish indicates that fried fish were preferred to the oven dried and smoked fish in terms of colour, flavor taste, and acceptability. While smoked fish was preferred in terms of texture. The study revealed that, smoked S. melanotheron has the highest nutritive value. Fried S. melanotheron was generally accepted based on taste and flavor. It is therefore recommended that S. melanotheron should be smoked or fried, because of their small sizes.
Fish Carboxyl Esterase Activity as a Possible Hypoxia Biomarker
Authors: FF Bastos
Published: January 2024

Physiology and biochemistry adaptations studied in fish are important to comprehend how they endure the challenges of living in aquatic environments. Oxygen variations are a frequent natural and cyclic phenomenon that occurs in the Pantanal and Amazon watersheds and it is the limiting factor to survival of the aerobic species. The growing of pollution in these water basins threaten many species as anthropic hypoxia intensifies the production of reactive oxygen species (ROS) and lipid peroxidation inside the cells, leading organisms to a condition known as oxidative stress. Our research group, studying the effects of the oxygen variations on the carboxyl esterase (CarbE) enzyme of pacu, a typical fish from Pantanal, observed that CarbE activity diminished by half in pacus exposed to 42 hours of hypoxia. Based on this finding, we decided to investigate this phenomenon in other fish species, including hypoxia-tolerant fishes. CarbE activities were determined using p-nitrophenyl acetate (p-NPA) as a substrate. All five species of fish studied had both serum and liver CarbE activity significantly decreased. Pacus had its serum and liver activities decreased by approximately 50% under severe hypoxia.
The Tip Nose
Authors: Fortes de Arruda Fabiano Calixto
Published: January 2024

Introduction: Rhinoplasty is a widely performed surgical procedure in plastic surgery. The development of knowledge regarding the anatomy of the nose represents one of the most refined aspects of plastic surgery education. A thorough understanding of each patient's nasal anatomy is crucial for achieving longer-lasting results. Therefore, knowledge of the nasal tip and its treatment is essential for the successful execution of rhinoplasty. The objective of this study is to describe the techniques used to treat the nasal tip. Discussion: The approach to the nasal tip is complex, involving both structural and aesthetic considerations. Various techniques are employed in the treatment of this region, including cartilage reduction, cartilage preservation, the use of specific sutures to shape the tip, and the use of cartilage to provide support. These techniques aim to improve function, prevent retraction, and enhance the definition of the nasal tip. Conclusion: This study outlines some of the most commonly used techniques in contemporary rhinoplasty, whether utilizing an open, closed, or hybrid approach. It is imperative for surgeons to be acquainted with these techniques and apply them based on individual indications for treating the nasal tip
Zenker diverticulum: Pathophysiology, Clinical Presentation, and Therapeutic Management
Authors: N Benkhraba
Published: January 2024

Zenker diverticulum (ZD) is attributed to a poorly compliant cricopharyngeus muscle, and the mainstay of treatment is a cricopharyngeal myotomy. We report the case of a patient of 78 years, diagnosed with Zenker diverticulum and we report diagnostic and therapeutic modalities.
Intravaginal Practices and Genital Infections: A Cross Sectional Study in the Yaoundé University Teaching Hospital
Authors: MC Ngonde-Essome
Published: January 2024

Cultural beliefs and educational factors strongly influence intravaginal practices of women in Sub Saharan Africa. These behaviors appear common in different population across Africa. Previous research has suggested that vaginal douching modifies vaginal flora and was associated with genital infections. The aim of this study was to evaluate the contribution of intravaginal practices in the acquisition of genital infections in women. For bacterial vaginosis diagnosis, vaginal smears were heat-fixed and Gram-stained then examined by light microscopy the results were interpreted by using a standardized method for diagnosing bacterial vaginosis, as described by Nugent. The mycological examination consisted of culturing on the CHROM agar Candida medium the vaginal swabs. The results were as follows: The majority of respondents were in the age group of 29-39 years (44%). The majority of participants were students with a prevalence of 42.60%. The results showed that 71% of women performed intravaginal practices and the most used vaginal practice was scraping the vaginal walls with the fingers (69.2%). Women with University level of education were statistically more adept at these practices (55.0%) than women with secondary level of education (30.8%) and primary level (14.2%) respectively, and the difference was significant (P<0.05).The prevalence of vaginal candidiasis in female who did intravaginal practices was higher (64.7%) than in those who did not do intravaginal practices (35.3%). Same result was observed with bacterial vaginosis which was more common in women who did intravaginal practices (76.6%). However, no significant association was found between intravaginal practices and the occurrence of vaginal candidiasis and bacterial vaginosis in women (P>0.05). Women who performed intravaginal practices were more co-infected with vaginal candidiasis and bacterial vaginosis (20.72%) than those who did not (10.34%); but the difference was not significant (p> 0.05). Intravaginal practices expose women to genital infections.
Ganz’s Anterior Dislocation for Intra-Articular Firearm Projectile Extraction and Fixation of Associated Femoral Head and Neck Fractures: Case Report
Authors: LS Seder
Published: January 2024

Hip fractures involving a firearm projectile are serious and complex injuries that represent a significant challenge for healthcare professionals. These fractures usually result from high-impact injuries caused by gunshots and can lead to extensive damage to tissue and bone structures. This type of injury can cause multiple, comminute fractures as well as damage to nearby blood vessels and nerves. The bullet fragment may remain and lead to poisoning, joint stiffness, pain, and further complications. The Ganz procedure is a surgical approach used in the treatment of femoral neck and head fractures. This method aims to restore the anatomy and biomechanics of the hip, especially in cases of complex or displaced fractures. Unlike traditional techniques, the Ganz procedure uses a less invasive approach, minimizing damage to surrounding tissues and preserving the region's vascularity. Hip fractures associated with gunshot wounds are rarely described in the literature. The objective of the present study is to report the use of the Ganz technique in a femur neck and head fracture associated with a firearm projectile in a 21-year-old male.
Occupancy of the Suprascapular Notch by the Suprascapular Nerve: An Anatomic Study
Authors: CK Yiannakopoulos
Published: January 2024

The purpose of the study was to evaluate the dimensions of the suprascapular nerve and the suprascapular notch in freshfrozen cadaveric shoulders and to calculate the occupancy ratio of the notch, i.e. the space occupied by the suprascapular nerve and the superior transverse scapular ligament (STSL). The suprascapular nerve and the suprascapular notch were dissected, and the following parameters were included in the study: presence and shaper of the notch, dimensions of the lower border of the superior transverse scapular ligament and dimensions of the notch and the dimensions of the suprascapular nerve in two directions perpendicular to each other. All measurements were performed using a digital Vernier caliper. The cross-sectional area of the suprascapular nerve was assumed to be elliptical; the area of a U-shaped notch was assumed to be semi-elliptical and the area of the triangular-shaped notch were calculated accordingly. The area of the between the various notch types and the cross-sectional area of the suprascapular nerve in the various notch types were statistically compared. The reliability of continuous measurements was analyzed using intraclass correlation coefficients (ICCs). The suprascapular notch was present in all cases. A U-shaped notch was the most common type (22, 69%) followed by a triangular-shaped notch (10, 31%). The interobserver reliability of the suprascapular nerve and notch dimensions was excellent (ICC = 0.92 and 0.96 respectively). The cross-sectional area of the suprascapular nerve was 5.982.34 mm2 with no difference between the two body sides. The cross-sectional area of the U-shaped suprascapular notch was significantly larger than that of the V-shaped notch (19.98 5.34 mm2 versus 13.777.34 mm2, p=0.02). Correspondingly, the occupancy of the suprascapular notch by the suprascapular nerve was higher in V-shaped rather than U-shaped notches (37.199.34% versus 49.417.32%, p=0.03).
A Case of Cartagenet's Syndrome Presenting as a Solid Pulmonary Lesion
Authors: Wenyong Yang
Published: January 2024

Background: Cartagena syndrome is a very rare disease with typical clinical manifestations of chronic sinusitis, bronchiectasis, and visceral inversion. Although it is not difficult to diagnose, many physicians do not pay enough attention to it, and it is often misdiagnosed or underdiagnosed. Here, we describe a patient with Cartagena syndrome who presented with solid pulmonary lesions on admission to the hospital. Case Details: A 15-year-old young woman with clinical symptoms such as cough, expectoration, nasal congestion, and runny nose came to the hospital this time due to the aggravation of cough and expectoration symptoms and chest pain. At admission, chest CT showed consolidation of the middle lobe of the left lung and inversion of the whole internal organs. After anti infection and expectorant treatment, the symptoms improved. Reexamination of chest CT showed that inflammation was obviously absorbed, the middle lobe bronchiectasis was obvious, and improved sinus CT showed extensive sinusitis, The final clinical diagnosis was Katane syndrome. Conclusion: It is not difficult to diagnose Cartagene syndrome with typical triad, but it is easy to miss or misdiagnose those with atypical imaging manifestations. For patients with lung consolidation and visceral inversion, we should think of the possibility of Cartagene syndrome, and timely review chest CT and improve relevant examinations to avoid missed diagnosis and misdiagnosis.
Is it Worthwhile Continuing to Live, If No One Really Cares about You? A Different Approach to Understanding Why So Many People Are Killing Themselves and What We Can do About It
Authors: Stein Gerald Samuel
Published: January 2024

America is experiencing a massive and accelerating number of people taking their own lives. Suicides have increased 33%, just since 1999, especially among veterans, women, and other young Americans. Over 45,000 suicides annually, making killing themselves the leading cause of death for youths ten to seventeen years old.
Nano Informatics: The Bridge between Nanotechnology and Data Science
Authors: Thangam Gopukumar Sivakumar
Published: January 2024

Nanotechnology, the manipulation of matter at the nanoscale, has emerged as a transformative field with profound implications for various industries, including medicine, electronics, energy, and materials science. The vast amount of data generated in nanotechnology research presents both an opportunity and a challenge. Nano informatics, a multidisciplinary field at the intersection of nanotechnology and data science, has evolved to harness the potential of data-driven insights in nanoscience and nanotechnology applications. The concept of nano informatics as a critical bridge between nanotechnology and data science. It highlights the significance of data collection, analysis, and interpretation in nanoscale research, emphasizing the need for advanced data-driven approaches to extract meaningful knowledge. Nano informatics not only plays a crucial role in managing the immense volume of data produced in nanotechnology experiments but also contributes to accelerating scientific discovery and innovation.
The Effect of Spiritual Leadership on the Spiritual Growth of Youth in Western Showa Dano District Seyo Town
Authors: Mengesha Megersa
Published: January 2024

Today's fast-paced digital world has an impact on people's spiritual lives, particularly those of young people. Christian youth should lead lives that are marked by development or progress. Young people require a leader who has a spiritual soul and can serve as a role model and life guide as they enter the process of maturing, particularly in terms of their spiritual development. Because of this, the necessity for leaders in human life has always changed with time and has always been a fascinating subject of conversation. A church leader is required to possess this spiritual leadership. This is due to the significant influence that church leaders have on Christian youth's spiritual development within the church. The purpose of this study is to ascertain how spiritual leadership affects young people's spiritual development. With 130 members, Seyo Evangelical Church of Mekane Iyesus youth, West Showa, served as the study's sample. Regression analysis is the analytic technique employed. The spiritual development of the fledgling Seyo Evangelical church of Mekane Iyesus is positively impacted by spiritual leadership. Youth spiritual growth will accelerate in the presence of strong spiritual leadership.
Agroecology and Sustainable Citriculture
Authors: Srivastava AK
Published: January 2024

Sustaining citriculture amidst climate change has become a more daunting challenge considering simultaneous occurrence of multiple nutrient deficiencies triggered by depleting carbon stock of soil coupled with glaring impact of global warming on crop performance. Despite paradigm shift from purely inorganic to either organic or the combination of two, agroecological applications have always occupied a center-stage in sustainable citriculture. Development of microbial consortium (microbial concoction), rhizosphere hybridization, identification of microbial corridor and microbial hot spot in a field, besides storing carbon in plant vegetative framework, are some of the upcoming ways to realize the multiple dimensions of agroecology in sustaining the citriculture in years to come with emphasis on on-farm research. These efforts have to be further matched with other natural resource conserving options like conservation agriculture, organic farming, natural farming to name a few important ones
Factors Related With Pneumonia among Children with Left-ToRight Shunt Congenital Heart Disease
Authors: Waworuntu David
Published: January 2024

Background: Infection is one of the major morbidities in congenital heart disease (CHD), especially pneumonia. Pneumonia in CHD has been known to increase overall morbidity and mortality. Early detection of pneumonia risk factors would help decrease the need for hospitalization, increase doctors’ awareness, and improve outcomes. Objective: To identify pneumonia’s incidence and risk factors in children with left-to-right shunt CHD. Method: This is a retrospective cohort study based on medical records of children aged 3 – 60 months hospitalized with diagnosis of any left-to-right shunt CHD with or without pneumonia in Cipto Mangunkusumo National Referral Hospital, Jakarta, in 2015-2019. Data of patients with CHD and pneumonia were retrieved from medical records based on ICD-10 codes. Patient’s clinical profiles were tested as possible risk factors for pneumonia: sex, age, birth weight, parental education, socioeconomic status, number of people in the house, nutritional status, type of heart defect, heart defect size, and immunization status. Bivariate analysis of parameters was done using the Chi square test. Parameters with a p-value less than 0.05 are included to multiple logistic regression test. Results: There were 333 subjects with left-to-right shunt CHD and 167 (50.2%) had pneumonia. The most common CHD type in pneumonia was ventricular septal defect (41.9%). The defect size was significantly related to pneumonia incidence (p=0.001). Risk factors identified to affect the occurrence of pneumonia in left-to-right shunt CHD were malnutrition [OR 5.152 (95% CI 2.363 – 11.234)], incomplete immunization [OR 9.689 (95% CI 4.322 – 21.721)], low socioeconomic status [OR 4.724 (95% CI 2.003 – 11.138)], and large defect [OR 5.463 (95% CI 1.949 – 15.307)]. Conclusion: The incidence of pneumonia in left-to-right shunt CHD was 50.2%, mostly in ventricular septal defects. Nutritional status, immunization status, socioeconomic status, and defect size were significant risk factors for pneumonia in children with left-to-right shunt CHD.
Case Report: Perimyocarditis in the Post-Partum Period
Authors: Lapitan Raul L
Published: January 2024

Perimyocarditis refers to an acute inflammation of the pericardium and the underlying myocardium. Following a viral infection is its most common etiology, with reported cases associated with COVID-19 infection. Perimyocarditis in pregnancy is rare and much so this case with symptoms of palpitation and dyspnea presenting two weeks post-partum.
Intraoperative Atrial Fibrillation: Insights from Five Clinical Cases and Mechanistic Elucidation
Authors: Khalil Abou Elalaa
Published: January 2024

Background: Atrial fibrillation (AF) occurring during non-cardiac procedures remains a complex clinical challenge. This article presents five clinical cases describing the occurrence of AF during non-cardiac surgery and explores the potential mechanisms behind this phenomenon. Methods: We retrospectively reviewed five cases of patients who developed AF during non-cardiac surgical procedures. Clinical profiles, electrocardiographic data and results of additional tests were analyzed to identify risk factors and possible mechanisms. Results: The cases presented included patients of different ages and clinical profiles, highlighting the variability of AF occurrence. Predisposing factors included perioperative stress, anesthetic use, electrolyte imbalances and underlying cardiac conditions. Potential mechanisms included electrophysiological changes, ionic imbalances and neurohormonal responses. Conclusion: This study highlights the complexity of intraoperative AF through a series of clinical cases. By understanding the risk factors and potential mechanisms, we can consider tailored preventive strategies to minimize the occurrence of AF during surgery. This deeper understanding paves the way for significant improvements in patients’ clinical outcomes.”
Trend of Global Mortality Due to Major Amputations in Chronic Threatening Ischemia of Lower Limbs
Authors: Zamora Jose Luis Cabrera
Published: January 2024

Worldwide, it is estimated that there are 202 million people with chronic PAD of the lower limbs, and that they present twice as many coronary events as the general population, with high mortality rates in the short, medium and long term. Despite the medical and revascularization treatments available for the management of lower limb PAD, major amputation (those performed above the ankle) remains a commonly used therapeutic option in advanced degrees of the disease. In the United States, this procedure is performed on 6.8% of patients hospitalized for PAD and when analyzed by groups, it reaches up to 15% to 20% of those diagnosed with chronic limb-threatening ischemia (CLI). Perioperative complication rates and 40.4% one-year mortality.