bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantum Vacuum Energy of Self-Similar Configurations
Authors: Cavero-Peláez Inés , Parashar Prachi , Shajesh K. V.
Published: May 2021

We offer in this review a description of the vacuum energy of self-similar systems. We describe two views of setting self-similar structures and point out the main differences. A review of the authors’ work on the subject is presented, where they treat the self-similar system as a many-object problem embedded in a regular smooth manifold. Focused on Dirichlet boundary conditions, we report a systematic way of calculating the Casimir energy of self-similar bodies where the knowledge of the quantum vacuum energy of the single building block element is assumed and in fact already known. A fundamental property that allows us to proceed with our method is the dependence of the energy on a geometrical parameter that makes it possible to establish the scaling property of self-similar systems. Several examples are given. We also describe the situation, shown by other authors, where the embedded space is a fractal space itself, having fractal dimension. A fractal space does not hold properties that are rather common in regular spaces like the tangent space. We refer to other authors who explain how some self-similar configurations “do not have any smooth structures and one cannot define differential operators on them directly”. This gives rise to important differences in the behavior of the vacuum.
Axion Electrodynamics and the Axionic Casimir Effect
Authors: Brevik Iver
Published: May 2021

A general scheme for axion electrodynamics is given, in which a surrounding medium of constant permittivity and permeability is assumed. Then, as an application, we provide simple numerical estimates for the electromagnetic current density produced by the electrically neutral time-dependent axions a=a(t) in a strong magnetic field. As is known, the assumption a=a(t) is common under astrophysical conditions. In the third part of the paper, we consider the implications by instead assuming an axion amplitude a(z) depending on one coordinate z only. If such an axion field is contained within two large metal plates, one obtains an axion-generated splitting of the eigenmodes for the dispersion relation. These modes yield equal, though opposite, contributions to the pressure on the plates. We calculate the magnitude of the splitting effect in a simple one-dimensional model.
High-Throughput Sequencing Indicates Novel Varicosavirus, Emaravirus, and Deltapartitivirus Infections in Vitis coignetiae
Authors: Nabeshima Tomoyuki , Abe Junya
Published: May 2021

Vitis coignetiae samples were collected from several locations in the northern area of Japan, and virome analysis using a high-throughput sequencing technique was performed. The data indicated that some of the collected samples were in mixed infections by various RNA viruses. Among these viruses, three were identified as newly recognized species with support of sequence identity and phylogenetic analysis. The viruses have been provisionally named the Vitis varicosavirus, Vitis emaravirus, and Vitis crypticvirus, and were assigned to the genus Varicosavirus, Emaravirus, and Deltapartitivirus, respectively.
Antiviral Activity Exerted by Natural Products against Human Viruses
Authors: Musarra-Pizzo Maria , Pennisi Rosamaria , Ben-Amor Ichrak , Mandalari Giuseppina , Sciortino Maria Teresa
Published: May 2021

Viral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity and mortality rates in humans. Natural products from plants or other organisms are a rich source of structurally novel chemical compounds including antivirals. Indeed, in traditional medicine, many pathological conditions have been treated using plant-derived medicines. Thus, the identification of novel alternative antiviral agents is of critical importance. In this review, we summarize novel phytochemicals with antiviral activity against human viruses and their potential application in treating or preventing viral disease.
Role of Transportin-SR2 in HIV-1 Nuclear Import
Authors: Tabasi Maryam , Nombela Ivan , Janssens Julie , Lahousse Adrien P. , Christ Frauke , Debyser Zeger
Published: May 2021

The HIV replication cycle depends on the interaction of viral proteins with proteins of the host. Unraveling host–pathogen interactions during the infection is of great importance for understanding the pathogenesis and the development of antiviral therapies. To date HIV uncoating and nuclear import are the most debated steps of the HIV-1 replication cycle. Despite numerous studies during past decades, there is still much controversy with respect to the identity and the role of viral and host factors involved in these processes. In this review, we provide a comprehensive overview on the role of transportin-SR2 as a host cell factor during active nuclear transport.
From Structural Studies to HCV Vaccine Design
Authors: Yechezkel Itai , Law Mansun , Tzarum Netanel
Published: May 2021

Hepatitis C virus (HCV) is a serious and growing public health problem despite recent developments of antiviral therapeutics. To achieve global elimination of HCV, an effective cross-genotype vaccine is needed. The failure of previous vaccination trials to elicit an effective cross-reactive immune response demands better vaccine antigens to induce a potent cross-neutralizing response to improve vaccine efficacy. HCV E1 and E2 envelope (Env) glycoproteins are the main targets for neutralizing antibodies (nAbs), which aid in HCV clearance and protection. Therefore, a molecular-level understanding of the nAb responses against HCV is imperative for the rational design of cross-genotype vaccine antigens. Here we summarize the recent advances in structural studies of HCV Env and Env-nAb complexes and how they improve our understanding of immune recognition of HCV. We review the structural data defining HCV neutralization epitopes and conformational plasticity of the Env proteins, and the knowledge applicable to rational vaccine design.
Structure-Based and Rational Design of a Hepatitis C Virus Vaccine
Authors: Guest Johnathan D. , Pierce Brian G.
Published: May 2021

A hepatitis C virus (HCV) vaccine is a critical yet unfulfilled step in addressing the global disease burden of HCV. While decades of research have led to numerous clinical and pre-clinical vaccine candidates, these efforts have been hindered by factors including HCV antigenic variability and immune evasion. Structure-based and rational vaccine design approaches have capitalized on insights regarding the immune response to HCV and the structures of antibody-bound envelope glycoproteins. Despite successes with other viruses, designing an immunogen based on HCV glycoproteins that can elicit broadly protective immunity against HCV infection is an ongoing challenge. Here, we describe HCV vaccine design approaches where immunogens were selected and optimized through analysis of available structures, identification of conserved epitopes targeted by neutralizing antibodies, or both. Several designs have elicited immune responses against HCV in vivo, revealing correlates of HCV antigen immunogenicity and breadth of induced responses. Recent studies have elucidated the functional, dynamic and immunological features of key regions of the viral envelope glycoproteins, which can inform next-generation immunogen design efforts. These insights and design strategies represent promising pathways to HCV vaccine development, which can be further informed by successful immunogen designs generated for other viruses.
Rotavirus as an Expression Platform of Domains of the SARS-CoV-2 Spike Protein
Authors: Philip Asha Ann , Patton John Thomas
Published: May 2021

Among vaccines administered to children are those targeting rotavirus, a segmented double-stranded RNA virus that represents a major cause of severe gastroenteritis. To explore the feasibility of establishing a combined rotavirus-SARS-CoV-2 vaccine, we generated recombinant (r)SA11 rotaviruses with modified segment 7 RNAs that contained coding cassettes for NSP3, a translational 2A stop-restart signal, and a FLAG-tagged portion of the SARS-CoV-2 spike (S) protein: S1 fragment, N-terminal domain (NTD), receptor-binding domain (RBD), extended RBD (ExRBD), or S2 core (CR) domain. Generation of rSA11 containing the S1 coding sequence required a sequence insertion of 2.2 kbp, the largest such insertion yet introduced into the rotavirus genome. Immunoblotting showed that rSA11 viruses containing the smaller NTD, RBD, ExRBD, and CR coding sequences expressed S-protein products of expected size, with ExRBD expressed at highest levels. These rSA11 viruses were genetically stable during serial passage. In contrast, the rSA11 virus containing the full-length S coding sequence (rSA11/NSP3-fS1) failed to express its expected 80 kDa fS1 product, for unexplained reasons. Moreover, rSA11/NSP3-fS1 was genetically unstable, with variants lacking the S1 insertion appearing during serial passage. Nonetheless, these results emphasize the potential usefulness of rotavirus vaccines as expression vectors of immunogenic portions of the SARS-CoV-2 S protein, including NTD, RBD, ExRBD, and CR, that have sizes smaller than the S1 fragment.
Bee Health and Productivity in Apis mellifera, a Consequence of Multiple Factors
Authors: Olate-Olave Verónica Rachel , Verde Mayda , Vallejos Leslie , Perez Raymonda Leonel , Cortese Maria Carla , Doorn Marnix
Published: May 2021

Managed honeybees play an important role as pollinators. The health and nutritional condition of honeybee colonies (Apis mellifera L.) depends for an important part on management practices, and it is influenced by multiple factors. This study aims to identify the stressors that lead to the loss of honeybee health and its consequences on the colony’s productivity. Different aspects related to management practices, productivity, clinical observations related to diseases, presence of sanitary gaps in the apiaries, colony strength, weather and infestation rates by Varroa sp. mites were measured. The information was collected during two monitoring in 53 apiaries in the Province of Santa Fe, Argentina. The results show correlations among many of the management practices, health condition and yield. The most important factors affecting the productivity of the studied honeybee colonies were nuclei preparation, the number of combs in the brood chamber, change of bee queen, disinfection of beekeeping material, among other less significant ones. Although honey production is important in the region, the colony strength was deficient and inadequate during both monitoring. Due to its dependence on management by the beekeeper, it is suggested that a holistic approach could improve bee health, increasing the productivity of honeybees.
The Sternberg Paradigm: Correcting Encoding Latencies in Visual and Auditory Test Designs
Authors: Klabes Julian , Babilon Sebastian , Zandi Babak , Khanh Tran Quoc
Published: May 2021

The Sternberg task is a widely used tool for assessing the working memory performance in vision and cognitive science. It is possible to apply a visual or auditory variant of the Sternberg task to query the memory load. However, previous studies have shown that the subjects’ corresponding reaction times differ dependent on the used variant. In this work, we present an experimental approach that is intended to correct the reaction time differences observed between auditory and visual item presentation. We found that the subjects’ reaction time offset is related to the encoding speed of a single probe item. After correcting for these individual encoding latencies, differences in the results of both the auditory and visual Sternberg task become non-significant, p=0.252. Thus, an equal task difficulty can be concluded for both variants of item presentation.
Três concepções acerca dos desastres
Authors: Cartaxo Sintilla Abreu , Shiota Ricardo
Published: May 2021

Este artigo de revisão bibliográfica objetiva apresentar três concepções sobre os desastres do ponto de vista sociológico. Na primeira abordagem, os desastres são a expressão de um agente externo intimidador, na segunda, os desastres traduzem a expressão social da vulnerabilidade e, por último, os desastres são vistos como um estado de incertezas geradas pelas próprias instituições.  A reflexão sociológica oferece um conhecimento aprofundado acerca das conexões sócio práticas produtoras de riscos e vulnerabilidades múltiplas, que a prevenção e a ação nos episódios de desastres demandam. O reconhecimento do vocabulário e dos diversos usos do conceito de desastre é de extrema importância para a formação daqueles que intervêm nas ocasiões de danos.
KİŞİSEL BİLGİSAYAR DONANIMI VE YAZILIM KULLANIM LİSANSININ HACZİ
Authors: KIYAK Emre
Published: May 2021

Kişisel bilgisayarlar sadece donanım unsurlarından meydana gelmeyip üstlendikleri fonksiyonları yerine getirebilmek için gayri maddi mal niteliğindeki yazılım olarak adlandırılan bileşenlere de ihtiyaç duyarlar. Bu durum, kişisel bilgisayarların hukuki niteliklerini belirlerken donanımlar ile yazılımlar noktasında farklı bakış açılarının benimsenmesini gerekli kılmaktadır. Kişisel bilgisayar donanımı eşya hukuk anlamında bir eşya topluluğu iken, yazılımlar ise fikri mülkiyet hukuku anlamında eser niteliğindedir. Kişisel bilgisayarın sahip olduğu bu özellikler, haciz işlemine konu olduklarında da böyle iki boyutlu bir bakış açısının benimsenmesi gerekeceğini ortaya koymaktadır. Buna göre bilgisayar donanımı haczedilirken bunun taşınır bir eşya olduğu göz önünde bulundurulacak, buna mukabil yazılımlar açısından haczin konusunu, aslında yazılımın kendisi değil, borçlunun bu yazılımı kullanmak için sahip olduğu lisans oluşturacaktır. Bu nedenle yazılım kullanım lisansları, taşınırların haczine dair hükümlere göre değil, intifa hakkının haczine ilişkin hükümler kıyasen uygulanmak suretiyle haczedilmelidir. Kişisel bilgisayarlar günümüzde temel ihtiyaç ya da mesleki ihtiyaç olması sebepleriyle haczi caiz olmayan mal niteliğine bürünebilirler. Bunun yanı sıra, ihtiva ettikleri kişisel veriler ve diğer önemli bilgilerden dolayı sabit disklerin – her ihtimalde – haczi caiz olmayan mal olarak edilmelidir.
PLATFORM ÇALIŞANLARININ HUKUKİ STATÜSÜ: UBER-ASLAM VE DİĞERLERİ KARARINA İLİŞKİN BİR DEĞERLENDİRME
Authors: KUTLU Merve
Published: May 2021

Teknolojinin ilerlemesi çalışma yaşamını önemli ölçüde etkilemekte ve değiştirmektedir. Çevrimiçi taksi hizmeti sunan Uber sürücülerinin hukuki statüsü önemli tartışmalara yol açmıştır. İngiliz Yüksek Mahkemesince verilen Uber-Aslam ve diğerleri kararı platform çalışanlarının hukuki statüsünün belirlenmesi ve dolayısıyla bağımlılık ilişkisine ilişkin son yıllarda verilmiş önemli kararlardan birisidir. Yüksek Mahkeme nihai kararını vermiş ve Uber sürücülerinin ‘‘çalışan’’ statüsünde olduklarını ve İş Hakları Yasasınca haklara sahip olduklarını belirlemiştir. Yüksek Mahkeme bağımlılığın belirlenmesinde; ücret ve hizmet sunumunun Uber tarafından belirlenmesi ve kontrol edilmesi, Uber’in sürücüler üzerinde uyguladığı kontrol, sürücülerin çalışmayı reddetme imkânı ve Uber sürücülerinin müşteri çevrelerini geliştirme imkânı olup olmadığı ölçütlerinden hareket etmiştir. Uber-Aslam kararında kullanılan ölçütler hukukumuzda da bağımlılığın ve dolayısıyla ‘‘işçi’’ statüsünün belirlenmesinde önem arz eder. Ancak her platform üzerinden iş gören kişilerin işçi olduğu sonucuna varmak kanaatimizce mümkün değildir. Bu yüzden, platform çalışmalarında bağımlılık unsuru, her somut olay bakımından öngörülen ölçütler uyarınca değerlendirilerek sonuca ulaşılmalıdır.
KEFALET SÖZLEŞMESİNİN GEÇERLİLİĞİ VE SONA ERMESİ BAKIMINDAN ASIL BORÇ
Authors: TAŞATAN Caner
Published: May 2021

Asıl borç, kefalet sözleşmesinin varlık ve geçerlilik koşullarından biridir. Kefalet sözleşmesinin kurulabilmesi için tarafların irade açıklamalarının asıl borç üzerinde birbirine uygun olması gerekir. Asıl borcun yokluğu durumunda kefalet sözleşmesi kurulmaz veya asıl borcun geçersiz olması durumunda kefalet sözleşmesi de geçersiz olur. Bu durum, kefaletin feriliği ilkesinin doğal bir sonucudur. Asıl borcun kefalet sözleşmesine olan etkisi bakımından getirilmiş kanuni düzenlemelerin sayısı sınırlıdır. Mevcut kanuni düzenlemeler ise yeterince açık değildir. Bu sebeple, asıl borcun kaynağı, konusu, henüz doğmuş olup olmadığı veya geciktirici yahut bozucu koşula bağlı olup olmadığı hususları ile asıl borcun geçersizliğinin veya sona ermesinin kefalet sözleşmesine olan etkileri tartışmalıdır. Bu çalışmada, belirtilen her bir durumun kefalet sözleşmesinin geçerliliğine veya sona ermesine olan etkileri, Türk ve İsviçre hukukları bakımından karşılaştırmalı olarak incelenmektedir.
Evaluación automática de la calidad de datos geoespaciales mediante servicios web
Authors: Xavier Emerson M. A. , Ariza-López Francisco J. , Ureña-Cámara Manuel A.
Published: May 2021

The geomatics sector is going through a data overload scenario which new geospatial datasets are generated almost daily. However there are few or nothing infor- mation about the quality of these datasets, and they should be evaluated aiming to provide users some information about their quality. In this context we propose a solution for the automatic quality evaluation of geospatial datasets using the web services platform. This approach is compound by automatic evaluation procedures for quality control of topological consistency, completeness, and positional accuracy described in the Brazilian quality standard. Some procedures require an external dataset for comparison purposes. Hence we provide a set of synthetic datasets and apply over them an experimental design aiming to select suitable methods to find the correspondences between datasets. The solution has an interoperability tier that links users and automatic procedures using the standardized interface of Web Processing Service (WPS). Our results showed that the automatic procedure works very similar to the manual one.
Optimización del proceso de barrenado del área del estabilizador vertical para disminuir defectos en una empresa del sector aeroespacial mediante la implementación de la metodología DMAIC
Authors: Chávez-Medina Juan , Santiesteban-López Noma Angélica , Sánchez-Flores Lizbeth , Cruz-de los Ángeles José Aurelio
Published: May 2021

Currently for organizations it is very important to comply with the satisfaction of both external and internal customers, in the same way it must comply with the established quality protocols, because the products that can be obtained can come to undermine the consumer's well-being final. The present work deals with this subject, however, it is necessary to specify that the company where the project was carried out will be determined as "Company A", due to a confidentiality contract. In which there is a process where holes are made in the skin of the vertical stabilizer with a semi-automated machine. At the end it is inspected, and it is noted that the countersink has marks which are visible or can be felt when the nail is passed over it. This problem causes operators to have to carry out this process again, but by hand so as not to exceed the established countersink measurement and leave it with a mirror polished aesthetic. The objective of this project is to minimize these defects that appear in the skin of the vertical stabilizer in the drilling process of "Company A", which have been generating rework in the production line. In this context, the importance of complying with quality problems would continue to contend in an increasingly strict market, seeking continuous improvement, standardization and control of processes, and customer satisfaction. The present identification work reduces and controls the sources of variation that are affecting the outputs of the vertical stabilizer barrier process, through the application of the DMAIC methodology (Define, Measure, Analyze, Improve, and Control. generated were favorable to the process and that in addition to the reduction of defects, other areas of improvement were found so that the affected process became standardized and controlled. Taking this into account, it is recommended that the methods and production department continue to work together, so that these defects do not continue to appear. Additional research can be done to identify other factors that indirectly affect the drilling process and this could be a great opportunity for the station.
Huella de carbono de una pavimentación con la metodología del ACV y SIMAPRO
Authors: Aceves-Gutierrez Humberto , López-Chávez Oscar , Mercado-Ibarra Santa Magdalena , Arevalo-Razo José Luis
Published: May 2021

The activities carried out by human beings are responsible for the greenhouse gas emissions that heat the planet and generate climate change. The best known gas is CO2, causing 63% of warming, which is generating consequences in the essential processes of our nature, as in the case of ecosystems, such as wetlands, are at risk of disappearing, the increase in temperature Average and decreasing rainfall, rising sea levels, decreased Arctic ice. The construction industry is one of the ways in which human beings pollute and one of them is due to urban growth and the demand for urban infrastructure, such as urban subdivision roads. The purpose of this study is to determine the KG-CO2 / M2 and the environmental impacts that are generated in the construction of an asphalt pavement in urban Development in Ciudad Obregón Sonora using the Life Cycle (ACV) methodology and the Simapro software. 9.0, using the required construction volumes. The results obtained of 13.6280 Kg-CO2 / M2.
Alternativa energética sustentable mediante la utilización de aislantes térmicos de diferentes materiales en edificaciones con sistemas de aire acondicionado
Authors: Casados-López Edzel Jair , Casados-Sánchez Alvaro , Cruz-Vicencio Raúl , Horst-Sánche Alvaro
Published: May 2021

A methodology is proposed for calculating the cooling load and the energy consumption of air conditioning equipment in three scale models of buildings under study, using the ASHRAE CLTD / SCL / CLF method. The building in which the mentioned method is used are three scale models of buildings located in the city of Poza Rica, state of Veracruz, Mexico. This method is applied in order to obtain the cooling load as exact as possible and thus avoid oversizing in air conditioning equipment, and by using thermal insulation, achieve a decrease in energy consumption and thus contribute to the reduction of CO2 emissions, to energy saving and therefore to sustainable development. The cooling load is calculated by applying the proposed methodology to three cases: model A, B and C. The results for the three test models, object of this study, are compared. Measurements of energy consumption are made to perform the error analysis of the actual energy consumption with respect to that calculated using the method. Finally, energy savings are quantified, in the cases mentioned.
HUBUNGAN MASA KERJA DAN SIKAP KERJA DENGAN KELUHAN CARPAL TUNNEL SYNDROME PADA PEKERJA PENENUN ULOS DI GALERI ULOS SIANIPAR MEDAN TAHUN 2020
Authors: Jehaman Isidorus , Julintina Monika , Br Ginting Luci Riani , Berampu Sabirin , Jannah Miftahul
Published: May 2021

Carpal tunnel syndrome is an eddy condition where the middle nerve is compressed in the wrist which results in parasthesia, numbness and muscle weakness in the hand. One nactor in the increasing number on carpal tunnel syndrome complaints is the outbreak on activities that use the hands especially those that carry out long periods on time. based on a preliminary study on 10 ulos weavers, there were 7 ulos weavers who had Carpal tunnel syndrome complaints in the norm on hand pain, tingling and numbness in the hands. The purpose on this study was to determine the relationship on work tenure and work attitude with complaints on carpal tunnel syndrome in ulos weaver workers at the Galery Ulos Sianipar Medan. The method in this study is an analytic observer research method with a cross sectional research approach. The respondents on this study are the ulos weavers in the Galery Ulos Sianipar Medan. Research instruments in the norm on questionnaires and measurement on phalen test data were analyzed by chi-square test. Based on the results on the study, the majority on ulos weavers experienced complaints on carpal tunnel syndrome as many as 34 people (65.4%). In this study it was nound that there was a relationship between work period (p = 0.003<0.05) with complaints on carpal tunnel syndrome, while work attitude (p = 0.399 >0.05) had no relationship with complaints on carpal tunnel syndrome. Suggestions nor ulos weaver workers are expected to take regular breaks by bending and straightening hands nor 3-5 minutes to reduce the risk on carpal tunnel syndrome
EFEKTIVITAS TABLET ZAT TERHADAP PERUBAHAN TEKANAN DARAH IBU HAMIL
Authors: . Damayanti , Gulo Nia Surtika , Anuhgerah Diah Evawanna , Handayani Dwi
Published: May 2021

Changes in blood pressure are normal during pregnancy. Because, the hormone progesterone which is produced during pregnancy, can relax the walls of blood vessels. Sagging walls of blood vessels, can reduce blood pressure in the first trimester and second trimester of pregnancy. This condition can cause dizziness when sitting or standing suddenly. Normal blood pressure values ​​in pregnant women do not differ from general conditions, which is 120/80 mmHg. If the blood pressure is recorded below 90/60 mmHg, this can indicate a blood pressure less.

This research aims to To find out how the effectiveness of iron tablets on changes in blood pressure of pregnant women at Rosni Alizar Pratama Clinic, Medan Timur District, Deli Serdang Regency in 2020. This type of research is a quasi-experimental study with a Pretest-Posttest with control group approach. The study population was all pregnant women who did ANC examination at Rosni Alizar Pratama Clinic as many as 38 people. The sample selection using purposive sampling was calculated using the Slovin formula of 28 people.

The results of the study used Wilcoxon test results obtained 0.157 and 1,000 > 0.05. It is expected that health workers on duty at the research site always measure vital signs for pregnant women during ANC visits.

Conclusion : There is no effectiveness in giving iron tablets to changes in blood pressure in pregnant women

Keywords: iron tablet, blood pressure, pregnant women
México For Sale. Inversión «sin límites» en la minería
Authors:   La Jornada, Valadez Rodríguez Alfredo ,   Proceso
Published: May 2021

México está en venta. Bajo la denominación de "fortalezas del país", el gobierno federal promueve abiertamente la inversión extranjera en la industria minera como parte de la estrategia del desarrollo. El capital extractivo de procedencia extranjera opera proyectos mineros que se encuentran en distintas etapas de desarrollo y producción. Ante la previsión de ganancias multimillonarias, la mayor parte de los proyectos está en etapa de exploración de depósitos minerales de oro y plata.
GAME OF THRONES IN CLASS (EPISODE 2). ¿IMPROVING GAMIFICATION REDUCES AMOTIVATION AND INCREASES SERVICE QUALITY IN CLASS?
Authors: Pelegrín-Borondo Jorge , Sierra-Murillo Yolanda , García-Milon Alba , Olarte-Pascual Cristina
Published: May 2021

The present research is based on the work of Pelegrín-Borondo et al. (2020) which analyzed the results of a gamification developed in order to reduce the degree of students’ amotivation in the subjects and to increase the service quality perception in teaching. Not satisfied with the results obtained, a new gamification is developed in the following year introducing some improvements obtained from the participating students’ feedback. This research gathers the results of the new gamification with the same subjects and teachers. Once again, the results are contrary to the expected and very similar to those obtained by Pelegrín-Borondo et al. (2020), which indicates that not all types of gamification diminish amotivation, nor does it increase the perception of quality in teaching. This research could be considered as exploratory and the problem may come from the design of the gamification itself. Thus, the present research gives advice to improve the design of a gamification and provides discussion on recent research about guidelines for planning an appropriate gamification given the work context.
Resumen

El presente trabajo parte de la investigación de Pelegrín-Borondo et al. (2020) en la que se analizan los resultados de una gamificación desarrollada con la finalidad de reducir el grado de amotivación de los estudiantes hacia las asignaturas y aumentar la percepción de la calidad del servicio en la docencia. No conformes con los resultados obtenidos, se desarrolla, en el curso siguiente una nueva gamificación en la que se introducen algunas mejoras obtenidas de la observación y escucha de los alumnos participantes. En esta investigación se recogen los resultados de la nueva gamificación realizada sobre las mismas asignaturas y con la participación de los mismos profesores. De nuevo, los resultados vuelven a ser contrarios a lo esperado y muy similares a los obtenidos por Pelegrín-Borondo et al. (2020), lo que indica que no todo tipo de gamificación disminuye la amotivación, ni aumenta la percepción de calidad en la docencia. Se considera que esta investigación es exploratoria y que el problema puede provenir del diseño de la gamificación. Así, se dan consejos para mejorar el diseño de una gamificación y se comentan investigaciones recientes que aportan directrices para planificar una gamificación adecuada al contexto de trabajo.
Características clínicas y epidemiológicas en adultos mayores con diagnóstico de fractura de cadera en un hospital de Lima, Perú.
Authors: Rondón Claudia N , Zaga Héctor V , Gutiérrez Ericson L
Published: May 2021

OBJETIVOS: Determinar las características clínicas y epidemiológicas en adultos mayores con fractura de cadera en un hospital de Lima, Perú. MÉTODO: Estudio tipo serie de casos realizado en el servicio de traumatología del Hospital Central PNP “Luis N. Sáenz” durante el periodo 2015-2018. Se revisaron historias clínicas de pacientes con diagnóstico de fractura de cadera. RESULTADOS: Se incluyeron un total de 140 historias. Se encontró predominio en el sexo femenino (54.3%) y en pacientes mayores de 80 años de edad (45%). Gran parte de estos eventos ocurrieron en el domicilio (81.4%). Las fracturas intertrocantéricas fueron las más frecuentes (60%), sobre todo del lado derecho (51.4%), la osteosíntesis fue la opción terapéutica más usada (62.1%). El dolor (92%) y la impotencia funcional (91.4%) fueron la presentación clínica característica de las fracturas de cadera y la hipertensión arterial la patología más frecuentemente asociada (52.2%). CONCLUSIONES: La fractura de cadera afecta primordialmente a personas mayores de 80 años, en especial al sexo femenino con elevada comorbilidad. El mayor porcentaje se da como resultado de caídas producidas en el domicilio, siendo el dolor del lado afectado la principal manifestación. El tipo de fractura más frecuente es la intertrocantérica y el tratamiento más usado, la osteosíntesis.
APPLICATION OF ECONOMETRIC MODELING IN THE EVALUATION OF FOREIGN ECONOMIC ACTIVITY OF UKRAINE
Authors: Plaskon Svitlana , Seniv Halina , Novosad Ivan , Masliy Vadym
Published: May 2021

Introduction. Foreign trade operations significantly affect the development of each country's economy, in particular the value of gross domestic product, which is one of the main indicators of economic development and welfare of population. Therefore, it is necessary to study and model the impact of exports, imports and net exports on macroeconomic indicators of Ukraine.
Purpose. The purpose of the article is to analyze publications that consider export-import operations of Ukraine, study of statistical information in this area, construction and analysis of econometric models of the dynamics of foreign trade operations of Ukraine and their impact on gross domestic product.
Method. The article uses regression-correlation analysis as one of the main research methods; time series theory; methods of mathematical modeling.
Results. The dynamics of foreign economic operations and gross domestic product of Ukraine are researched and analyzed. It is revealed that the balance of export-import operations has a significant impact on the gross domestic product of Ukraine. An econometric model of the dependence of the nominal gross domestic product on the value of exports of goods and services (coefficient of determination 0.9795) is calculated, using statistical information for 2005-2019 years. It is substantiated that with the increase in exports of goods and services by UAH 1 billion Ukraine's nominal GDP grows by an average of UAH 2.2642 billion. The value of coefficients of import dependence and coverage of import by export in foreign economic operations of Ukraine are analyzed. It is noted that the coefficient of import dependence significantly exceeds the allowable level in the study period, due to certain imbalances in foreign trade relations. The coefficient of coverage of imports by exports only in 2005 was greater than one, and during 2006-2019 it became less than one. In this regard, it is necessary to increase export operations, obtain a positive balance of payments, make effective economic and political decisions to increase exports of Ukrainian goods and services, reduce import dependence, using and implementing innovative methods of production and management.
APPLICATION OF THE FORMALIZATION THEORY TO RESEARCHES ON ECONOMIC PROCESSES IN THE WORLD ECONOMIC ACTIVITY
Authors: Serazhym Yulian
Published: May 2021

Approaches to understanding and defining the concept of formalization in various fields of science (philosophy, linguistics, logic, mathematics, computer science) are considered. Attention is drawn to the fact that the issue of formalization is considered in many areas of human activity, mainly as: a method of scientific research; method of logic, which consists in replacing semantic terms with signs, symbols and formulas; a means of transforming empirical and scientific knowledge into scientific information.
There are three strategic interrelated and interdependent aspects of formalization: the first, related to the disclosure of uncertainty, which is often combined with the problem of isolating the field of scientific research as a priority of formalization theory; second, the use of modern formalization theory as a tool for finding existing directions in the development of scientific thought; third, so far this scientific field, despite its underdevelopment, can be used to identify global and domestic trends in economic activity, influencing the solution of existing problems of humanization in the process of adaptation to globalization: restructuring economic specialization or maintaining high competitiveness in world economy. The principles of using formalization as a method in economics, which help to determine the logical structures of concepts, categories and laws in the process of research: logical sequence, consistency, completeness, independence. The relationship between formalization and the evolution of artificial intelligence and modern creative theory has been traced.
THE CONCEPTUAL FOUNDATIONS OF TRANSACTIONAL ANALYSIS OF PUBLIC FINANCE
Authors: Derlytsia Andrii
Published: May 2021

Introduction. One of the least developed areas of the theory of economic institutionalism is transactional analysis of public finance. Its component – the theory of transaction costs, is mainly applied to the sphere of functioning of economic entities and the financial market. This necessitates the study of transactions in public finance as an economic phenomenon that requires an integrated approach and goes beyond purely transaction costs.
The purpose of the article. The aim is to study the conceptual foundations, method and key areas of transactional analysis of public finance as a scientific field of institutional research.
Method. To achieve this goal, the following general scientific methods were used: scientific abstraction, in highlighting the essential features of transactional analysis of public finance; comparative analysis, when assessing the differences in transaction costs in the public and market sectors; a systematic approach in identifying the components of transactional analysis of public finance.
Results. Transactional analysis of public finance as a component of institutional research of public finance is considered. The role of transaction costs in the public sphere is shown and their ability to positively influence the efficiency of public finance due to the optimization of resource allocation in the public sector is substantiated. It is indicated that transaction costs in the public sphere are a necessary element to ensure compliance with supply and demand of public goods and other state services, which leads to increased utility of participants in collective interaction. The characteristic of the method of transactional analysis of public finance and its features is given. The main directions of transactional analysis of public finance from the standpoint of comparison of transaction costs, transaction losses and transaction benefits are outlined. The dualistic nature of transaction costs in relation to transformation costs is shown.
FORECASTING THE OBJECTIVE NUMBER OF HIGHER EDUCATION INSTITUTIONS IN RELATION TO MODERN FACTORS
Authors: Ruska Ruslana , Aliluiko Andrii , Plaskon Svitlana , Novosad Ivan
Published: May 2021

Introduction. Education is an indicator of the country's intellectual potential. Higher education is a strategic resource through which the state is competitive in the global labour market.complete higher education attests to the professional and cultural level of a considerable number of the population, especially young people, and is not only an indicator of economic growth but also of social stability. The purpose of investigation was determined by the analysis of current state of higher education institutions and the main influencing factors for them. The coefficient of interest of graduates in receiving higher education in Ukraine is determined on the basis of regression analysis. Arima models were constructed using time series theory for prediction of the number of higher education institutions for future periods.
Purpose. The purpose of the study is the construction the predictive models of the dynamics of the number of future students and the number of higher education institutions in Ukraine.
Methodology. Regression analysis is used as one of the main methods of scientific research in the process of writing the article; time series theory, in particular Arima modeling of the Statistica application package; methods of mathematical modeling, in particular approximating polynomials in the process of modeling the dynamics of the institutions of higher education and the number of students, to determine the ‘coefficient of interest’.
Results. The study found that the number of institutions of higher education depends on the one hand on the time factor, on the other – on the number of students. Given that the number of students and the amount higher education institutions can be characterized as a dynamic process, the theory of time series, in particular Arima modelling, was applied.
Using Arima models, the number of students and the number of higher education institutions for the next two years is predicted. The relative errors for these models are 6% and 0. 4%, respectively.
Based on statistics on the number of graduates of all secondary education institutions and the number of students admitted to higher education institutions of Ukraine, a ‘coefficient of interest’ in higher education was derived, which allows predicting the number of future entrants.
The Arima model predicts the number of Ukrainian students in foreign educational institutions.
The obtained forecast values regarding the number of students, the amount of higher education institutions of Ukraine, by various methods, adequately reflect the real situation today.
KEY ASPECTS OF IMPROVEMENT OF METHODOLOGICAL APPROACHES TO FUNCTIONING OF THE MECHANISM OF INNOVATIVE-INVESTMENT DEVELOPMENT OF ENTERPRISES
Authors: Demchenko Pavlo
Published: May 2021

The study shows the importance of innovation and investment in economics, management and business. Some key theoretical aspects of the essence of the methodology of formation of the mechanism of innovation and investment activity and development of iron ore enterprises in modern economic conditions are determined. It is established that the lack of funding for iron ore enterprises requires effective management and rational organization of both individual stages of capital investment in their innovation activities and the investment process as a whole. At the same time, the most significant and important for the organization of investment in innovative business processes of iron ore enterprises is the application of a systematic approach. In the context of improving the mechanism of innovation and investment development of the iron ore enterprise, it is proposed to carry out a multi-criteria assessment of the level of stability of sustainable innovation and investment development, taking into account the risk.
The implementation of the proposed recommendations for improving the management mechanisms of innovation and investment development of mining and processing enterprises based on the theory of potential and a systematic approach to the organization of investment in innovation processes in periods characterized by the most characteristic states of the economic environment in terms of market transformations. «Stagnation» and «recession», where weight point estimates that reflect higher priority for retrospective periods, for which less contributions were made to the total value of the evaluation function of innovation and investment development are calculated on the basis of quantitative estimates of the risk matrix.
Summarizing the research of theoretical and methodological aspects of assessing the level of stability of sustainable innovation and investment development of the iron ore enterprise, a system of conditions for controlling the level of stability of sustainable innovation and investment development (RZSSIIR) has been formed. The formed system of conditions of control of RZSSIIR of the iron ore enterprise is directed on maintenance of effective strategic management at the expense of strengthening of a role of investments in innovation management for realization of process of acceptance of long-term decisions.
ORGANIZATION OF ACCOUNTING AND DISTRIBUTION OF OVERALL PRODUCTION EXPENSES AT STATE ENTERPRISES OF CRIMINAL ENFORCEMENT SERVICE
Authors: Khmelyuk Alona , Rukavitsyna Natalia
Published: May 2021

Introduction. The basic principles and normative-legal regulation of the organization of the account, including the administrative (internal) account of the state enterprise are considered. It is emphasized that the organization of accounting at a state-owned enterprise is carried out in accordance with the current national legislation and is declared through the formation of the Order on Accounting Policy. It is established that the main internal administrative document of the organization of accounting, including the accounting of expenses at the state enterprise is the Order on the organization of the account and accounting policy. A comparative analysis of the Order on accounting policy in terms of declaring the formation and reflection of costs in the accounts and methods of calculating the production cost of products; list and composition of articles of calculation of production cost of production (works, services); bases of distribution of general production variables and distributed fixed costs and their actual reflection. Thus, having studied the method of calculating a unit of production (work robe) and the reflection of business transactions in the system of accounting accounts, some differences with the Order on Accounting Policy. The expediency of application of the normative method of calculation of the prime cost of production is confirmed and the algorithm of calculation of the prime cost of a dressing gown is defined. An assessment of the reflection of overhead costs in the system of accounting accounts at a state-owned enterprise. The inconsistency of the accounting principles declared in the Order on Accounting Policy in terms of cost formation, in particular the cost of production, has been established. Effective methods of improving the accounting of overhead costs at the state enterprise of the penitentiary service are proposed.
Purpose. Assess external and internal regulatory approaches to the organization of management (internal) accounting in Ukraine, present the features of the formation of accounting information on costs at the state enterprise, develop recommendations for improving the methodological aspects of accounting and distribution of overhead costs at state enterprises.
Method (methodology). Method of system analysis, methods of cause and effect analysis, tabular and graphical methods.
Results. The inconsistency of application in practice of the principles and methods of accounting at the state enterprise of the penitentiary service in accordance with the declared Order on Accounting Policy; identified violations in the formation and distribution of overhead costs for production costs; the analysis of the current methods of organization of cost accounting at the state enterprise is carried out; the algorithm for calculating the unit cost of production is presented; proposed improvement of the organization of accounting for overhead costs in order to comply with common methodological approaches to cost accounting.
ENERGY SERVICE CONTRACT AS A SPECIAL FORM OF ENERGY EFFICIENCY
Authors: Mykytyuk Petro , Galysh Nataliya
Published: May 2021

Introduction. One of the central problems of business organization at all stages of the history of civilization is the problem of resource and financial support. Absolutely typical even for large and stable companies can be considered a situation when they feel lack of funding for the implementation of a particular investment program, for example, in the field of construction, technical re-equipment, etc.
The development of the energy services market in Ukraine is constrained by objective reasons, which are equally characteristic of other countries in which these services have become widespread or are just being implemented. The reasons for that are imperfect legislation, lack of the necessary methodology, high financial and political risks. As the experience of other countries shows, it may take from 3 to 5 years for the energy services market to function properly. During this period, the necessary changes have been made to the legislation, the methodology of measuring and verifying energy saving resources, selection and evaluation of energy service projects have been developed and improved, institutes of development and financial support of energy service companies have been created, available banking products have been appear. Therefore, it is safe to say that the development of energy services in Ukraine is still subject to general trends.
Objective – definition of types of performance contracts, their characteristics. Specification of conditions for the implementation of energy service contracts in the market of these services.
Method (methodology). The methodological basis of the study were the theoretical provisions on the functioning of the energy market.
Results. The main conditions of performance contracts have been determined, which allow to distinguish energy service companies among a number of organizations and firms engaged in energy audit. Conditions that are advantages that the energy service provides in comparison with the contract or economic way of carrying out energy saving measures.