bluuebunny/crossref_metadata_2025 huggingface dataset:
Post-trans-arterial chemoembolization hepatic necrosis and biliary stenosis: Clinical charateristics and endoscopic approach
Authors: Cocca Silvia , Carloni Lorenzo , Marocchi Margherita , Grande Giuseppe , Bianchini Marcello , Colecchia Antonio , Conigliaro Rita , Bertani Helga
Published: December 2023

Liver cancer is the fifth most common tumor and the second highest death-related cancer in the world. Hepatocarcinoma (HCC) represents 90% of liver cancers. According to the Barcelona Clinic Liver Cancer group, different treatment options could be offered to patients in consideration of tumor burden, liver function, patient performance status and biochemical marker serum concentration such as alpha-fetoprotein. Trans-arterial chemoembolization (TACE) is the treatment of choice in patients with diagnosis of unresectable HCC not eligible for liver transplantation, and preserved arterial supply. TACE is known to be safe and its complications are generally mild such as post-TACE syndrome, a self-resolving adverse event that occurs in about 90% of patients after the procedure. However, albeit rarely, more severe adverse events such as biloma, sepsis, hepatic failure, chemoagents induced toxicities, and post-TACE liver necrosis can occur. A prompt diagnosis of these clinical conditions is fundamental to prevent further complications. As a result, biliary stenosis could be a rare post-TACE necrosis complication and can be difficult to manage. Complications from untreated biliary strictures include recurring infections, jaundice, chronic cholestasis, and secondary biliary cirrhosis.
Significance of fostering the mental health of patients with diabetes through critical time intervention
Authors: Eseadi Chiedu , Amedu Amos Nnaemeka , Aloh Henry Egi
Published: December 2023

BACKGROUND

Critical time intervention (CTI) is an evidence-based model of practice that is time-limited and aims to provide support for most susceptible individuals during a transition period.

AIM

To examine the significance of fostering the mental health of diabetes patients through CTI using the scoping review methodology.

METHODS

As part of the scoping review process, we followed the guidelines established by the Joanna Briggs Institute. The search databases were Google Scholar, PubMed, Scopus, PsycINFO, Reference Citation Analysis (https://www.referencecitationanalysis.com/ ), and Cochrane Library. From these databases, 77 articles were retrieved with the aid of carefully selected search terms. However, 19 studies were selected after two reviewers appraised the full texts to ensure that they are all eligible for inclusion, while 54 papers were excluded.

RESULTS

This study revealed that diabetic patients who had experienced homelessness were at higher risk of being diagnosed with mental illness and that social support services are impactful in the management of the comorbidity of diabetes and mental health problems. In addition, this review reveals that CTI is impactful in enhancing the mental health of homeless patients during the transitional period from the hospital through social support services.

CONCLUSION

CTI is a promising intervention for alleviating mental health symptoms in homeless patients. Empirical studies are needed across the globe, involving both hospitalized and community-based patients, to determine how clinically effectively CTI is in managing the mental health of diabetics.
Iatrogenic flexor tendon rupture caused by misdiagnosing sarcoidosis-related flexor tendon contracture as tenosynovitis: A case report
Authors: Yan Rui , Zhang Zhe , Wu Long , Wu Zhi-Peng , Yan He-De
Published: December 2023

BACKGROUND

Sarcoidosis is a multisystem disease characterized by granuloma formation in various organs. Sarcoidosis-related flexor tendon contractures are uncommon in clinical settings. This contracture is similar to stenosing tenosynovitis and potentially leads to misdiagnosis and mistreatment. Herein, we report a rare case of sarcoidosis-related finger flexor tendon contracture that was misdiagnosed as tenosynovitis.

CASE SUMMARY

A 44-year-old woman presented to our department with flexion contracture of the right ring and middle fingers. The patient was misdiagnosed with tenosynovitis and underwent acupotomy release of the A1 pulley of the middle finger in another hospital that resulted in iatrogenic rupture of both the superficial and profundus flexors. Radiological presentation showed multiple sarcoid involvements in the pulmonary locations and ipsilateral forearm. A diagnosis of sarcoidosis was made based on the presence of non-caseating granulomas with tubercles consisting of Langhans giant cells with lymphocyte infiltration on biopsy, and the patient underwent surgical repair for the contracture. After 2 mo, the patient experienced another spontaneous rupture of the repaired middle finger tendon and underwent surgical re-repair. Satisfactory results were achieved at the 10 mo follow-up after reoperation.

CONCLUSION

Sarcoidosis-related finger contractures are rare; thus, caution should be exercised when dealing with such patients to avoid incorrect treatment.
Post-laparotomy heterotopic ossification of the xiphoid process: A case report
Authors: Lee Seung Soo
Published: December 2023

BACKGROUND

Heterotopic ossification (HO) represents all types of extraskeletal ossification in the body. It occurs in various areas, including the skin, subcutaneous tissue, muscle, and joints. Surgical excision is recommended for symptomatic HO. Postoperative radiotherapy, oral nonsteroidal anti-inflammatory drugs, and topical sealants, such as bone wax, have been recommended as preventive measures. As HO is rare in occurrence, these recommendations are based on personal experiences, and there is a lack of information on individualized treatments depending on its location.

CASE SUMMARY

A 62-year-old male was admitted for symptomatic HO along a laparotomy scar. Surgical excision was performed for an 11 cm-sized ossification originating from the xiphoid process, and bone wax was applied to the excisional margin. However, the surgical wound failed to heal. After several weeks of saline-soaked gauze dressing, delayed wound closure was performed. The patient was finally discharged eight weeks after the excision. Because HO can occur in various areas of the body, a treatment strategy that may be effective for some may not be for others. Bone wax has been used as a topical sealant over excisional margins in the shoulder, elbow, and temporomandibular joints. However, in our case, its application on an abdominal surgical wound delayed its primary healing intention. The valuable lesson was that, when choosing a treatment method for HO based on available research data, its location must be considered.

CONCLUSION

Complete excision should be the priority treatment option for symptomatic HO along the laparotomy scar. Bone wax application is not recommended.
Balloon displacement during caesarean section with pernicious placenta previa: A case report
Authors: Gu Deng-Feng , Deng Chao
Published: December 2023

BACKGROUND

For the past few years, preventive interventional therapy has been widely used domestically and overseas, bringing great benefits to pregnant women at high-risk for complications, such as pernicious placenta previa (PPP) and placenta accreta. Nevertheless, there are still few reports on surgical complications related to interventional therapy, and its safety should be a concern.

CASE SUMMARY

We report a 36-year-old pregnant woman with PPP who underwent balloon implantation in the lower segment of the abdominal aorta before caesarean section. However, the balloon shifted during the operation, which damaged the arterial vessels after filling, resulting in severe postpartum haemorrhage in the patient. Fortunately, after emergency interventional stent implantation, the patient was successfully relieved of the massive haemorrhage crisis.

CONCLUSION

It seems that massive postoperative bleeding has been largely avoided in preventive interventional therapy in high-risk pregnant women with placenta-related diseases, but surgical complications related to intervention therapy can also cause adverse consequences. It is equally important for clinical doctors to learn how to promptly identify and effectively treat these rare complications.
Effects of video game-based therapy in an adolescent with cerebral palsy: A case report
Authors: Mohd Iqbal Huda Aliah , Ho Wei Sheng , Zanudin Asfarina , Hisham Hafifi , Mohd Nordin Nor Azlin
Published: December 2023

BACKGROUND

Herein, we report the case of a 13-year-old boy with spastic quadriplegia cerebral palsy (CP) at Gross Motor Function Classification System (GMFCS) level II, engaging in a 6-wk video game-based therapy (VBT) program. This study aimed to offer essential insights regarding VBT’s impact on enhancing the physical function and improving the quality of life (QoL) of adolescents diagnosed with CP. This report provides a distinctive viewpoint that can inform and direct future clinical practices and research endeavors.

CASE SUMMARY

The boy presented with moderate mobility, balance, and overall well-being. He faced challenges with diminished lower limb strength, which affected his daily living and physical fitness capabilities. Our participant was diagnosed with spastic quadriplegic CP at GMFCS level II. He participated in a 6-wk program of VBT using a play station. This innovative approach incorporates warm-up exercises, interactive activities, and cool-down routines, targeting various movements, including single-leg stance, weight shifting, kicking, jumping, marching, and squatting. After VBT, the strength of the left hip extensor significantly increased from 199.3 N to 541.3 N. Distance covered as part of a 6-min walk test increased by 82 m. His Paediatric QoL Inventory score increased dramatically by 25.9%.

CONCLUSION

VBT is an innovative, individualized therapy that enhances physical function and QoL in CP, emphasizing its role in ambulatory patients.
Automatic Management Zone Delineation For Center Pivot Variable Rate Irrigation Using Field Data
Authors: Nguyen Anh T. , Thompson Allen  L. , Sudduth Kenneth A. , Vories Earl D.
Published: December 2023

Highlights

A computer model (MOPivot) was developed to determine unique management areas.

MOPivot can delineate management zone maps for center pivot (CP) variable rate irrigation (VRI) systems.

The CP system achieved high application uniformity over a range of VRI application depths.

MOPivot management zone maps were evaluated using soil survey geographic database (SSURGO) and soil apparent

electrical conductivity (ECa) data.

Abstract. Concerns over water availability and water quality increasingly require more efficient use of water resources in irrigated agriculture. Center pivot (CP) systems designed with variable rate irrigation (VRI) technology have the potential to improve application and water-use efficiency while reducing environmental impacts from excess runoff and poor water quality. The objective of this study was to develop a computer model (MOPivot) to automate management zone delineation for irrigation scheduling based on the minimum area that can be controlled by the CP system (based on sprinkler spacing and location, and wetted diameter) matched to VRI capabilities and GIS site-specific grid-based field data affecting water storage and runoff. To ensure that the CP was capable of meeting scheduled VRI prescriptions, application uniformity was validated along the lateral length for sprinkler pulse percentages of 20 to 100 percent using catch collectors spaced 3-m apart along thirteen radial lines (82 m long, beginning 68 m from the pivot point and covering 10° of pivot rotation) for both clockwise and counter-clockwise rotation. Results indicated that the system achieved high application uniformity over a range of VRI application depths. The MOPivot management zones were in close agreement with GIS grid-based soil survey geographic database (SSURGO) and soil apparent electrical conductivity (ECa) derived soil texture input data (82.8% and 93.5% overall accuracy, respectively). The model successfully established the minimum azimuthal angle and sector length for VRI zone-control VRI and automatically delineated management zones useful in developing Keywords: Center pivot, Irrigation prescription, Sprinkler zone, Variable rate irrigation.
HCNN-LSTM: Hybrid Convolutional Neural Network with Long Short-Term Memory Integrated for Legitimate Web Prediction
Authors: Zonyfar Candra , Lee Jung-Been , Kim Jeong-Dong
Published: December 2023

Phishing techniques are the most frequently used threat by attackers to deceive Internet users and obtain sensitive victim information, such as login credentials and credit card numbers. So, it is important for users to know the legitimate website to avoid the traps of fake websites. However, it is difficult for lay users to distinguish legitimate websites, considering that phishing techniques are always developing from time to time. Therefore, a legitimate website detection system is an easy way for users to avoid phishing websites. To address this problem, we present a hybrid deep learning model by combining a convolution neural network and long short-term memory (HCNN-LSTM). A one-dimensional CNN with a LSTM network shared estimation of all sublayers, then implements the proposed model in the benchmark dataset for phishing prediction, which consists of 11430 URLs with 87 attributes extracted of which 56 parameters are selected from URL structure and syntax. The HCNN-LSTM model was successful in binary classification with accuracy, precision, recall, and F1-score of 95.19%, 95.00%, 95.00%, 95.00%, successively outperforming the CNN and LSTM. Thus, the results show that our proposed model is a competitive new model for the legitimate web prediction tasks.
Machine Learning Approaches for Fake Reviews Detection: A Systematic Literature Review
Authors: Ennaouri Mohammed , Zellou Ahmed
Published: December 2023

These days, most people refer to user reviews to purchase an online product. Unfortunately, spammers exploit this situation by posting deceptive reviews and misleading consumers either to promote a product with poor quality or to demote a brand and damage its reputation. Among the solutions to this problem is human verification. Unfortunately, the real-time nature of fake reviews makes the task more difficult, especially on e-commerce platforms. The purpose of this study is to conduct a systematic literature review to analyze solutions put out by researchers who have worked on setting up an automatic and efficient framework to identify fake reviews, unsolved problems in the domain, and the future research direction. Our findings emphasize the importance of the use of certain features and provide researchers and practitioners with insights on proposed solutions and their limitations. Thus, the findings of the study reveals that most approaches focus on sentiment analysis, opinion mining and, in particular, machine learning (ML), which contributes to the development of more powerful models that can significantly solve the problem and thus enhance further the accuracy and efficiency of detecting fake reviews.
A perspectiva sindical da implantação da Indústria 4.0: o Caso da Mercedes-Benz
Authors: Ramalho Martins Fernando , Muniz Júnior Jorge , Oliveira dos Santos João Paulo
Published: December 2023

Inovações organizacionais e tecnológicas constantemente desafiam tomadores de decisão e os papéis desempenhados por estes. Este é o pano de fundo do caso de ensino ora em tela. Nele, a partir do relato de representantes trabalhistas, busca-se apresentar um dilema imposto por um contexto industrial adverso que exigiu criatividade e flexibilidade dos tomadores de decisão, sejam eles representantes da organização ou dos trabalhadores. Dessa forma, busca-se colocar o aluno no papel de liderança empresarial ou sindical a fim de que desenvolva seu pensamento criativo e encontre soluções inovadoras que muitas vezes desafiam os papéis tradicionalmente desempenhados pelos agentes organizacionais. O dilema que se apresenta implica em necessidade de trabalho em equipe e capacidade de criação de consenso. O caso privilegia um ponto de vista nem sempre enfatizado no mundo acadêmico, o ponto de vista sindical.
Why implants fail?
Authors: Barrak Fadi
Published: December 2023

An overview of the currently recognised causes of implant failure and the evidence for emerging competing theories.
The Multi-Local Dynamics of the Pataxó in Belo Horizonte, Brazil: Indigenous Relationships with the State, Economic Activities, and Family Networks / Dinâmicas multilocais dos Pataxó em Belo Horizonte, Brasil: relações entre Estado, atividades econômicas, e redes familiares
Authors: Campos Thiago Barbosa de , Campos Marden Barbosa de , Horn Philipp
Published: December 2023

abstract: Drawing on in-depth empirical research with members of the Pataxó Indigenous group in the Belo Horizonte metropolitan region, Brazil, this article moves beyond spatially fixed understandings of Indigenous territoriality. Instead, it demonstrates that Indigenous territoriality should be understood as multi-local, spanning rural and urban locations within and beyond a national territory. We analyse a series of interrelated multi-local territorial practices by the Pataxó and demonstrate how their mobility is shaped by relationships with the state, engagement in economic activities, and family ties. Our research shows that the Pataxó are engaged in continuous territorial movements and that each territory is insufficient—although all are necessary—for these people to meet their diverse needs. We argue that looking at these mobility dynamics relationally allows for a more holistic conceptualisation of Indigenous territoriality. Our work is based on original empirical research and makes connections to wider trends that have been observed in several metropolitan regions in Latin America. resumo: Com base em uma pesquisa empírica com membros da etnia indígena Pataxó na Região Metropolitana de Belo Horizonte, Brasil, este artigo vai além de entendimentos espacialmente fixos da territorialidade indígena. Em vez disso, demonstra que a territorialidade indígena deve ser entendida como multilocal, abrangendo locais rurais e urbanos dentro e fora de um território nacional. Analisamos uma série de práticas territoriais multilocais dos Pataxó e demonstramos como sua mobilidade é moldada pelas relações com o Estado, pelo envolvimento em atividades econômicas e pelas redes familiares. Nossa pesquisa mostra que os Pataxó estão envolvidos em movimentos territoriais contínuos e que cada território é insuficiente-embora todos sejam necessários-para que os indígenas atendam às suas diversas necessidades. Argumentamos que analisar essa dinâmica de mobilidade de forma relacional permite um entendimento mais abrangente da territorialidade indígena. Nosso trabalho se baseia em uma pesquisa empírica original e faz conexões com tendências observadas em outras regiões metropolitanas da América Latina.
Recogitating the Heinz Brücher Story: A Nazi Biologist in the Crosshairs of History / Repensando la historia de Heinz Brücher: un biólogo nazi en la mira de la historia
Authors: Gadea Daniel W.
Published: December 2023

abstract: This article explores the life and work of Heinz Brücher (1915-1991), a German-born biologist who lived and worked in South America during the latter half of the twentieth century. It revisits the author's previous research on this enigmatic researcher, his work, and his past in Nazi Germany (Gade, 2006a), to add further information to the story, correct previously printed mistakes, provide new insights into the presence of Nazi scientists in South America, and continue the exploration of the profound ways ideology can affect or distort science. resumen: Este artículo explora la vida y obra de Heinz Brücher (1915-1991), un biólogo de origen alemán que vivió y trabajó en América del Sur durante la segunda mitad del siglo XX. Revisa la investigación previa del autor sobre este enigmático investigador, su trabajo y su pasado en la Alemania nazi (Gade, 2006a), para agregar más información a la historia, corregir errores impresos previamente, proporcionar nuevos conocimientos sobre la presencia de científicos nazis en América del Sur y continuar la exploración de las formas profundas en que la ideología puede afectar o distorsionar la ciencia.
NeuroD1-GPX4 signaling leads to ferroptosis resistance in hepatocellular carcinoma
Authors: Huang Ping , Duan Wei , Ruan Cao , Wang Lingxian , Hosea Rendy , Wu Zheng , Zeng Jianting , Wu Shourong , Kasim Vivi
Published: December 2023

Cell death resistance is a hallmark of tumor cells that drives tumorigenesis and drug resistance. Targeting cell death resistance-related genes to sensitize tumor cells and decrease their cell death threshold has attracted attention as a potential antitumor therapeutic strategy. However, the underlying mechanism is not fully understood. Recent studies have reported that NeuroD1, first discovered as a neurodifferentiation factor, is upregulated in various tumor cells and plays a crucial role in tumorigenesis. However, its involvement in tumor cell death resistance remains unknown. Here, we found that NeuroD1 was highly expressed in hepatocellular carcinoma (HCC) cells and was associated with tumor cell death resistance. We revealed that NeuroD1 enhanced HCC cell resistance to ferroptosis, a type of cell death caused by aberrant redox homeostasis that induces lipid peroxide accumulation, leading to increased HCC cell viability. NeuroD1 binds to the promoter of glutathione peroxidase 4 (GPX4), a key reductant that suppresses ferroptosis by reducing lipid peroxide, and activates its transcriptional activity, resulting in decreased lipid peroxide and ferroptosis. Subsequently, we showed that NeuroD1/GPX4-mediated ferroptosis resistance was crucial for HCC cell tumorigenic potential. These findings not only identify NeuroD1 as a regulator of tumor cell ferroptosis resistance but also reveal a novel molecular mechanism underlying the oncogenic function of NeuroD1. Furthermore, our findings suggest the potential of targeting NeuroD1 in antitumor therapy.
Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial
Authors: Ackland Gareth L. , Martin Tim , Joseph Mareena , Dias Priyanthi , Hameed Rizwan , Gutierrez del Arroyo Ana , Hewson Russ , Abbott Tom E. F. , Spooner Oliver , Bhogal Pervinder
Published: December 2023

Background

Labile blood pressure after acute ischaemic stroke requiring mechanical thrombectomy is independently associated with poor patient outcomes.

Objectives

This study protocol describes is designed to determine whether transauricular nerve stimulation, improves baroreflex sensitivity, reduces blood pressure variability in the first 24 hours after acute ischaemic stroke requiring mechanical thrombectomy.

Design: Phase 2A, proof-of-concept, sham-controlled randomised trial

Methods and Analysis: 36 individuals undergoing mechanical thrombectomy for acute ischaemic stroke with established hypertension aged >18 years will be randomly allocated to receive bilateral active or sham transauricular nerve stimulation for the duration of the mechanical thrombectomy procedure (AffeX-CT/001 investigational device). The intervention will be repeated for 1h the morning following the mechanical thrombectomy. Non-invasive blood pressure will be measured ≥2h for 24h after mechanical thrombectomy. Holter electrocardiographic monitoring will be recorded during transauricular nerve stimulation. Participants, clinicians and investigators will be masked to treatment allocations. The primary outcome will be the coefficient of variation of systolic blood pressure. Secondary outcomes include additional estimates of blood pressure variability and time/frequency-domain measures of autonomic cardiac modulation An adjusted sample size of 36 patients is required to have a 90% chance of detecting, as significant at the 5% level, a difference in the coefficient of variation in systolic blood pressure of 5±4mmHg between sham and active stimulation [assuming 5% non-compliance rate in each group].

Ethics: confirmed on 16 March 2023 by HRA and Health and Care Research Wales ethics committee (reference 23/WA/0013)

Discussion

This study will provide proof-of-concept data that examines whether non-invasive autonomic neuromodulation can be used to favourably modify blood pressure and autonomic control after acute ischaemic stroke requiring mechanical thrombectomy.

Trial registration

Trial registration number: NCT05417009.
Effects of medical and surgical treatment on vitamin D levels in obesity
Authors: Mejaddam Ala , Höskuldsdóttir Gudrún , Lenér Frida , Wallenius Ville , Trimpou Penelope , Fändriks Lars , Mossberg Karin , Eliasson Björn , Landin-Wilhelmsen Kerstin
Published: December 2023

Introduction

Persons living with obesity treated with bariatric surgery are at a high risk of developing nutritional deficiencies. The primary aim of this observational cohort study was to compare vitamin D levels in patients two years after bariatric surgery (Roux-en-Y gastric bypass/RYGB and sleeve gastrectomy/SG) with a very low-energy diet (VLED). The same subjects were also compared with a population sample from the same region at baseline. The primary hypothesis was that surgery, especially RYGB, would lead to an increased prevalence of vitamin D deficiency compared to subjects treated with VLED. 971 individuals eligible for surgical, RYGB (n = 388), SG (n = 201), and medical treatment (n = 382), in routine care, were included consecutively between 2015 and 2017. A random population sample from the WHO-MONICA project was used as a reference, (n = 414). S-calcium, S-25(OH)D (vitamin D), and S-PTH (parathyroid hormone) were measured in all persons with obesity at baseline and two years after treatment (n = 713). Self-reported use of vitamin D and calcium supplementation was registered.

Results

Vitamin D deficiency (S-25(OH)D <25mmol/l) was found in 5.2% of the persons with obesity at baseline versus 1.7% of the general population (SMD>0.1). S-25(OH)D increased for all treatment groups but was higher in RYGB and SG (SMD>0.1, standardized mean difference). Thirteen subjects (1.8%) had vitamin D deficiency after obesity treatment.

Conclusion

Surgical intervention for obesity followed by vitamin D supplementation was not associated with a higher risk for vitamin D deficiency, irrespective of surgery type, compared to individuals on medical treatment. However, persons living with obesity seeking weight loss treatment are more likely to have deficient vitamin D levels compared to the general population.
GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats
Authors: Azizian Hossein , Farhadi Zeinab , Bader Michael , Alizadeh Ghalenoei Jalil , Ghafari Mohammad Amin , Mahmoodzadeh Shokoufeh
Published: December 2023

Postmenopausal diabetic women are at higher risk to develop cardiovascular diseases (CVD) compared with nondiabetic women. Alterations in cardiac cellular metabolism caused by changes in sirtuins are one of the main causes of CVD in postmenopausal diabetic women. Several studies have demonstrated the beneficial actions of the G protein-coupled estrogen receptor (GPER) in postmenopausal diabetic CVD. However, the molecular mechanisms by which GPER has a cardioprotective effect are still not well understood. In this study, we used an ovariectomized (OVX) type-two diabetic (T2D) rat model induced by high-fat diet/streptozotocin to investigate the effect of G-1 (GPER-agonist) on sirtuins, and their downstream pathways involved in regulation of cardiac metabolism and function. Animals were divided into five groups: Sham-Control, T2D, OVX+T2D, OVX+T2D+Vehicle, and OVX+T2D+G-1. G-1 was administrated for six weeks. At the end, hemodynamic factors were measured, and protein levels of sirtuins, AMP-activated protein kinase (AMPK), and uncoupling protein 2 (UCP2) were determined by Western blot analysis. In addition, cardiac levels of oxidative stress biomarkers were measured. The findings showed that T2D led to left ventricular dysfunction and signs of oxidative stress in the myocardium, which were accompanied by decreased protein levels of Sirt1/2/3/6, p-AMPK, and UCP2 in the heart. Moreover, the induction of the menopausal state exacerbated these changes. In contrast, treatment with G-1 ameliorated the hemodynamic changes associated with ovariectomy by increasing Sirt1/3, p-AMPK, UCP2, and improving oxidative status. The results provide evidence of the cardioprotective effects of GPER operating through Sirt1/3, p-AMPK, and UCP2, thereby improving cardiac function. Our results suggest that increasing Sirt1/3 levels may offer new therapeutic approaches for postmenopausal diabetic CVD.
Coaching styles and sports motivation in athletes with and without Intellectual Impairments
Authors: Sakalidis Kandianos Emmanouil , Hettinga Florentina Johanna , Ling Fiona Chun Man
Published: December 2023

The cognitive limitations of athletes with Intellectual Impairments (II) may influence their sport behaviour and lead them to rely on coaches’ support. However, it is still unclear how II may influence sports performance progression and motivation and how coaches perceive their athletes with II and coach them. Thus, this study aims to examine 1) coach’s perceptions of motivation and performance progression in athletes with and without II, 2) coaching style (dis)similarities, and 3) the association between these factors. Coaches of athletes with (n = 122) and without II (n = 144) were recruited and completed three online questionnaires, analysed using a series of non-parametric analyses (p ≤ .05). Results showed that perceived performance progression and controlled motivation were higher of athletes with II while perceived autonomous motivation was higher of athletes without II. No coaching style differences were found between the two groups. Additionally, a need-supportive coaching style negatively predicted amotivation, and a need-thwarting coaching style predicted lower autonomous motivation in athletes with II only. Overall, it seems that the coaches perceived that their athletes with II demonstrate different motivations and react dissimilarly to their coaching styles compared to athletes without II. They may also adopt different standards of sporting success for them. Due to these differences, it is important to offer appropriate training and knowledge to coaches about disability sports and the adaptations needed to effectively coach athletes with II. In summary, this paper gives some insights about the coach-athlete relationship and highlights the necessity to further support the sports development of people with II.
Implementation of the advanced HIV disease care package with point-of-care CD4 testing during tuberculosis case finding: A mixed-methods evaluation
Authors: Gils Tinne , Kamele Mashaete , Madonsela Thandanani , Bosman Shannon , Ngubane Thulani , Joseph Philip , Reither Klaus , Bresser Moniek , Vlieghe Erika , Decroo Tom , Ayakaka Irene , Lynen Lutgarde , Van Heerden Alastair
Published: December 2023

During TB-case finding, we assessed the feasibility of implementing the advanced HIV disease (AHD) care package, including VISITECT CD4 Advanced Disease (VISITECT), a semiquantitative test to identify a CD4≤200cells/μl. Adult participants with tuberculosis symptoms, recruited near-facility in Lesotho and South-Africa between 2021–2022, were offered HIV testing (capillary blood), Xpert MTB/RIF and Ultra, and MGIT culture (sputum). People living with HIV (PLHIV) were offered VISITECT (venous blood) and Alere tuberculosis-lipoarabinomannan (AlereLAM, urine) testing. AHD was defined as a CD4≤200cells/μl on VISITECT or a positive tuberculosis test. A CD4≤200cells/μl on VISITECT triggered Immy cryptococcal antigen (Immy CrAg, plasma) testing. Participants were referred with test results. To evaluate feasibility, we assessed i) acceptability and ii) intervention delivery of point-of-care diagnostics among study staff using questionnaires and group discussions, iii) process compliance, and iv) early effectiveness (12-week survival and treatment status) in PLHIV. Predictors for 12-week survival were assessed with logistic regression. Thematic content analysis and triangulation were performed. Among PLHIV (N = 676, 48.6% of 1392 participants), 7.8% were newly diagnosed, 81.8% on ART, and 10.4% knew their HIV status but were not on ART. Among 676 PLHIV, 41.7% had AHD, 29.9% a CD4≤200cells/μl and 20.6% a tuberculosis diagnosis. Among 200 PLHIV tested with Immy CrAg, 4.0% were positive. The procedures were acceptable for study staff, despite intervention delivery challenges related to supply and the long procedural duration (median: 73 minutes). At 12 weeks, among 276 PLHIV with AHD and 328 without, 3.3% and 0.9% had died, 84.8% and 92.1% were alive and 12.0% and 7.0% had an unknown status, respectively. Neither AHD nor tuberculosis status were associated with survival. Implementing AHD care package diagnostics was feasible during tuberculosis-case finding. AHD was prevalent, and not associated with survival, which is likely explained by the low specificity of VISITECT. Challenges with CD4 testing and preventive treatment uptake require addressing.
Research ethics and collaborative research in health and social care: Analysis of UK research ethics policies, scoping review of the literature, and focus group study
Authors: De Poli Chiara , Oyebode Jan
Published: December 2023

Current research ethics frameworks were developed on the footprint of biomedical, experimental research and present several pitfalls when applied to non-experimental social sciences. This work explores how the normative principles underpinning policy and regulatory frameworks of research ethics and the related operational processes work in practice in the context of collaborative health and social care research. The work was organised in three phases. First, UK research ethics policy documents were analysed thematically, with themes further organised under the categories of ‘Principles’ and ‘Processes’. Next, we conducted a scoping review of articles about research ethics in the context of collaborative health and social care research, published in English between 2010 and 2022. We then held an exploratory focus group with ten academic researchers with relevant experience to gather their views on how the research ethics system works in practice in England (UK). The thematic framework developed in the first phase supported the analysis of the articles included in the scoping review and of focus group data. The analysis of policy documents identified twelve themes. All were associated to both a principle and a related operational process. The scoping review identified 31 articles. Across these, some themes were barely acknowledged (e.g., Compliance with legislation). Other themes were extensively covered (e.g., The working of Research Ethics Committees), often to discuss issues and limitations in how, in practice, the research ethics system and its processes deal with collaborative research and to suggest options for improvement. Focus group data were largely consistent with the findings of the scoping review. This work provides evidence of the poor alignment between how the research ethics system is normatively expected to work and how it works in practice and offers options that could make research ethics more fit for purpose when addressing collaborative research in health and social care.
How to measure earnings surprises: Based on revised market reaction
Authors: Pan Qin , Huang Kai
Published: December 2023

We investigate the robustness of earnings surprise measures in the context of a revised market reaction. While existing literature suggests that financial anomalies may distort cumulative abnormal returns (CAR) during annual announcements, our research proves that a revised market reaction offers a more accurate reflection of investor reactions to earnings correction. Specifically, we introduce an innovative adjustment to CAR using stock price jumps, and prove that the fraction of misses on the same side (FOM) provides a superior measure of earnings surprises. Furthermore, we find that investor trading patterns align with FOM, and the post-earnings announcement drift (PEAD) strategy based on FOM outperforms that based on analysts’ forecast error.
Marking the moment: Documenting dance in coloured water, flesh, sand and charcoal
Authors: Akinleye Adesola
Published: December 2023

This article discusses interdisciplinary methods for recalling and documenting the somatic knowledges derived from movement (such as dance movement). The article explores the research-as-practice interdisciplinary activity of Concrete-Water-Flesh at Deptford, a set of three structured improvisational dance scores carried out on the sand by the River Thames at Deptford, United Kingdom in 2020 and 2021. During Concrete-Water-Flesh at Deptford, I, Helen Kindred and some fellow dancers (forming DancingStrong Movement Lab Company) moved across the sand at the river’s edge, while fine artists (including Andrew Hinton, Mary Rodriguez and Nina Anderson) moved across paper, drawing us using elements from the shore (the sandy sludge, charcoal from burnt beach debris, and water). In the moment of dance, the marks of our movements (such as on sand or on paper) offered a documentation of the somatic experience of Concrete-Water-Flesh at Deptford. I suggest the collaboration of Concrete-Water-Flesh at Deptford raises possibilities for, and further questions about, documenting and languaging the embodied.
Using digital touch in the process of improvising and the implications for kinaesthesia
Authors: Rees Katherine
Published: December 2023

The Digital Touch Project took place between 2019 and 2020 and is part of wider research considering wearable technology in dance-making. In questioning the use of body-worn digital tools/aids in the dance-making process, the project aimed to discover more about how technology-assisted creativity operates and its influence. Six experienced dancers/choreographers utilized the prototypes in their choreographic practices. The workshops enabled data collection via a mixed-method approach of semi-structured interviews, embodied participation (researcher as a participant), fieldnotes and movement analysis from video footage. The coded data and thematic analysis have been collated with the transcribed movement and provide evidence towards two different forms of digital touch and its promotion of heightened attentional focus, greater fluidity of interoceptive and exteroceptive abilities within improvisation and varied working relationships with the prototypes.
An embodied methodology for site-specific transpersonal research in the arts
Authors: Kerr Margaret , Pamphilon Joseph
Published: December 2023

This article proposes a methodology and theoretical foundation for practice-based transpersonal research in the arts, which involves an immersive engagement with place and matter. This kind of engagement allows the artist-researcher to move beyond their conscious mind, to let work emerge directly from the felt experience of being in an outdoor location and from the interaction of the place’s materiality with the artist’s body. The model is interdisciplinary and draws on Nagotomo’s Attunement through the Body (1992), the theoretical literature of parapsychology, somatic practice and and others’ writings on Indigenous methodologies.
Editorial
Authors: Hayward-Smith Lily , Kim Eugenia S. , Petts Louisa , Stamp Kathryn
Published: December 2023

This editorial for the 15.2 open call issue of Journal of Dance & Somatic Practices (JDSP) introduces the articles and reviews contained in this issue, whilst also giving an update on journal news, developments and recent activity.
Of divas and diaries: Externalizing the internal in Trevor
Authors: Coon David R.
Published: December 2023

This article examines the Oscar-winning film Trevor, paying particular attention to how the filmmakers depict the public/external and private/internal aspects of the title character’s identity as he comes to terms with being gay and navigates the coming-out process. The backbone of the film’s narrative is a series of diary entries voiced aloud by Trevor, granting the viewer access to his private thoughts. The film’s soundtrack, consisting mostly of songs by Diana Ross, further externalizes Trevor’s private feelings while linking him to queer culture through his worship of a gay icon. Through a discussion of these elements, this article argues that Trevor uses its narrative structure along with various visual and sonic techniques to illuminate the public and private aspects of coming out in a productive and empowering way.
Interview with Marco Calvani about The View from Up Here (2017)
Authors: Felando Cynthia
Published: December 2023

This article features an interview with Marco Calvani, the award-winning playwright and director, and critically acclaimed short film auteur, about his film The View from Up Here.
Microaggression and proxemics in The View from Up Here
Authors: Mazzarotto Marci
Published: December 2023

This article explores how proxemics (by way of cinematography and other formal strategies) as well as microaggressions are brilliantly deployed throughout The View from Up Here in order to demonstrate a racist power dynamic – one that is inherently tied to the manner in which deeply damaging stereotypes of migrants and refugees are not only created and reinforced by the mass media but also subsequently disseminated by audiences.
Inventory of Migratory Water birds in the coastal areas of Purba Medinipur district, West Bengal, India.
Authors: Basu Roy Arjan , Chatterjee Lina , Khan Anupam , Panja Balaram , Samanta Tarak , Jana Samik
Published: December 2023

The present study was done on migratory water birds in the coastal and surrounding areas of Purba Medinipur, West Bengal, India from July 2020 to June 2022. A total number of 51 migratory water bird species belonging to 7 orders and 10 families were recorded during this study. Among the recorded species 45 species were the Least Concern (LC) and 4 were Near Threatened (NT) and 1 species each were Vulnerable (VU) and Endangered (EN). Scolopacidae was represented as highest family of 16 species because aggregation of migratory waders birds during winter season. The overall Shannon Diversity Index (H’) was 0.892 and the Shannon Evenness (J’) value was 0.226. The Simpson’s Diversity Index (D) was 0.286. All the diversity Index were lowest because of dominating Lesser Whisting-duck Dendrocygna  javanica (Horsfield, 1821) (9015) aggregate in the coastal wetlands and bheries during winter season. In future more focus will be on this areas as there are many places still not properly explored and several wetlands which need to be studied in a thorough manner for a better understanding about the migratory avian diversity of this area.
Las visitas generales a la Audiencia de Quito en el siglo XVII: un ensayo de historia comparada
Authors: Ponce Leiva  Pilar
Published: December 2023

Dentro de la revisión a la que están siendo sometidos los mecanismos de control de la corrupción utilizados por la Monarquía Hispánica, las visitas generales han recuperado la atención de los investigadores, siendo objeto de nuevos análisis que, a su vez, generan nuevas valoraciones. Teniendo en cuenta que las visitas presentan una casuística muy acusada, en este texto se experimentará con una metodología poco frecuente en la materia: el método comparado. Los objetos de comparación serán las dos visitas generales realizadas a la Audiencia de Quito en el siglo XVII, que se analizarán a partir de las mismas variables. La amplia y variada gama de factores coyunturales hace arriesgada cualquier valoración taxativa sobre la utilidad de los mecanismos de control empleados, pero las visiones comparativas permiten una mayor ponderación de su impacto social y político.
La visita del oidor Juan de Villabona a la gobernación de Cartagena de Indias entre 1609 y 1612. Los abusos de los encomenderos y de los curas doctrineros
Authors: Córdoba Ochoa Luis Miguel , Gómez González Sebastián
Published: December 2023

En este texto se examinarán las pesquisas que practicó el oidor Juan de Villabona Zubiaurre en la gobernación de Cartagena de Indias durante la visita de la tierra que realizó a esa provincia entre 1609 y 1612. La visita fue ordenada por la Audiencia de Santa Fe como consecuencia de las denuncias que se recibieron en ella y en el Consejo de Indias sobre los abusos y violencias que los encomenderos cometían contra los indígenas. Se analizarán los procedimientos que utilizó el oidor para informarse acerca de dichos abusos y se estudiarán algunas de las formas como los indígenas dieron testimonio de la violencia recibida por parte de los encomenderos al ser interrogados por el doctor Villabona.
THE INFLUENCE OF INTEGRATION PROCESSES ON THE DEVELOPMENT OF NATIONAL LEGAL SYSTEMS OF POST-SOVIET COUNTRIES
Authors: Mokhorova Anna Yu. , Demidov Vladimir P. , Dolzhenkova Ekaterina
Published: December 2023

As part of the convergence, the national legal systems of a number of states that emerged in the early 90s of the twentieth century acquired features characteristic of the Romano-German legal family, and therefore the fundamental principles of law that are implemented within the development models of these countries have acquired a qualitatively new nature, reflecting the fundamental transformations of the state-political structure. The purpose of the study is to consider the features of the national legal systems of the post-Soviet countries, formed under the influence of integration processes of a legal nature that occurred on the territory of the former republics of the USSR. The objectives of the study are to study the main trends of a state-legal nature, to identify the influence of international law norms on the legislation of new subjects of international relations, as well as to establish the influence of the integration of several states into various interstate associations on national legal systems. Formal-legal, analytical, and historical-legal research methods are used to achieve the results. The study found that the national legal systems of the states that were previously part of the USSR are organically oriented towards regulatory requirements implemented within the framework of international organizations of which they are members, which leads to a certain unification of the regulation of public relations, which does not exclude the preservation of national legal traditions. The process of convergence of the legal systems of individual post-Soviet countries is slow, uneven, not always progressive, but nevertheless lays the foundations for joint activities on several issues that go beyond the jurisdiction of a particular State or require joint efforts for effective solutions.