bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role and Importance of Women in the Revitalization of Intangible Heritage in Order to Maintain the Competitiveness of the Destination
Authors: Vuković Dijana , Varlaj Sanja , Simić Sara
Published: July 2023

Within the Croatian intangible cultural heritage, traditions and customs, due to their specific functions, occupy a unique place in tourism. The oral transmission of tradition, the culture of memory is manifested in the contemporary application of traditional customs as the most vital mod­el of duration, regardless of the new way of life in which traditional customs have lost their significance. This paper aims to highlight women’s role in tra­dition’s transference – a practice that belongs to women within the frame­work of intangible cultural heritage, but also female creativity which is closely related to sustainable tourism. Protected cultural goods of intangi­ble heritage represent forms of cultural expression of particular importance in a certain area. Their historical roots testify to their exceptional value from a historical, artistic, ethnographic, sociological, anthropological, linguistic, or literary point of view. Intangible cultural heritage, which is passed down from generation to generation, provides a sense of identity and continuity and thus promotes respect for cultural diversity and human creativity. The paper aims to point out the role of intangible cultural heritage as a genera­tor of destination development and the active role of women.
Assessment of the Economic Situation of Post-socialist EU Countries
Authors: Petrušová Dagmar , Kráľová Katarína , Sochuľáková Jana
Published: July 2023

The economic development of Slovakia, as well as other former socialist countries, was largely marked by the transition from a centrally planned economy to a market economy. This process was long and difficult. Post-socialist countries were forced to adopt a broad complex of political, social, economic and institutional reforms that made the business environ­ment in the country more attractive and strengthened economic growth. This process of transformation continues and despite progress there is room for further improvement even in the most developed post-socialist coun­tries. In addition, the economy of individual countries, as well as the world economy, is currently significantly affected by the ongoing pandemic, and it has also been negatively affected by the war conflict in Ukraine and the emerging energy crisis. In the article, we will focus on evaluating and comparing the development and economic situation of former socialist countries that have since become members of the European Union. Based on selected macroeconomic indica­tors, we will assess the level of the economy of individual countries. Subse­quently, we will use the ranking method and compile and evaluate the rank­ing of the analyzed countries.
The Level of Development – Students’ Perceptions and Beyond: The Case of Balkan Countries
Authors: Šimić Vladimir , Malešević Perović Lena
Published: July 2023

This paper investigates the level of development in Balkan coun­tries through comparison of the common development indicators. A start­ing point is the perception of the level of economic development by a group of first year economics students at the Faculty of Economics, Business and Tourism in Split, Croatia. With the students typically not being aware (fa­miliar) of how rich (poor) their country is, this study provides a deeper inves­tigation of the level of development of Croatia and compares it with sever­al countries from the neighborhood. The investigation employs commonly used indicators of economic development – GNI (Gross national income) per capita as usually reported by the World Bank, but also takes into account additional indicators like HDI (Human development index) and life satisfac­tion indicator. Overall, the study provides an interesting review and compar­isons between countries and resolves some misperceptions that are typical­ly present in general public.
Impact of the Ukrainian Crisis on Investments in Online Market in Slovakia
Authors: Čobrda Vlastimir
Published: July 2023

This article provides a comprehensive analysis of the impact of the Ukrainian crisis on investments in marketing and the online market in Slovakia, in the context of the largest military conflict in Europe since World War II. Given the changing perception of normality in society and the signif­icant impact of economic sanctions against Russia by the EU and the US on the global macroeconomic picture, the paper focuses on the Slovak online market as a relevant case study. The article first examines the current state of the online market in Slovakia and the influence of political and economic factors on its development. It is analyzed how economic sanctions and geopolitical tensions, directly and indirectly, affected the business of Slovak companies in various segments. In the second part of the paper, the needs and opportunities for the improve­ment of the online market in Slovakia are reviewed, taking into account the current challenges and uncertainties. As the main goal of this work, the author wants to show how the current cri­sis, caused by the events in Ukraine, can be successfully overcome by adapt­ing the market to the new rules of business, using the experience and knowl­edge gained during the crisis years during the Covid-19 pandemic. The pa­per ends by summarizing the key conclusions and provides recommenda­tions for further development of this topic, to encourage experts, research­ers and decision-makers to work together to solve the challenges brought about by the Ukrainian crisis.
Analysis of Agriculture in the European Union
Authors: Mrvica Mađarac Sandra , Filipović Zvonimir , Jurić Sandra
Published: July 2023

With its agricultural policy, the European Union wants to encour­age member states to invest in agricultural production, production and pro­motion of quality agricultural products, care for the environment, develop­ment of rural areas, increase market transparency, and encourage innova­tion in agriculture. The main challenges for agricultural production in the European Union are global market competition, economic and political cri­ses, climate change and rising costs of production factors. The European Union wants to provide support for the sustainable income of agricultural holdings and the stability of the agricultural sector, and it contributes great­ly to the financing of agriculture in the member states. In this way, the aim is to ensure the long-term security of the food supply and the agricultural diversity of the member states. The paper states the objectives of the agri­cultural policy of the European Union, researches and analyzes data on the number of employees in agriculture, the age structure of farmers, the size of agricultural holdings, agricultural and livestock production, fishing and promotional activities of agricultural production in the European Union.
ФОРМУВАННЯ ЗДОРОВОГО СПОСОБУ ЖИТТЯ СТУДЕНТСЬКОЇ МОЛОДІ ЗАСОБАМИ ФІЗИЧНОГО ВИХОВАННЯ
Authors: Данилко Валентина , Кравченко Тетяна
Published: July 2023

Анотація.
Вступ. У статті акцентовано увагу на тому, що формування цінностей здорового способу життя студентів вищих навчальних закладів у процесі фізичного виховання – це насамперед формування системи відповідних ціннісних орієнтацій і установок, активної життєвої позиції студентів, їх позитивної мотивації до саморозвитку та самовдосконалення, прийняття відповідальності за власне здоров’я і самореалізацію в соціальному і професійному середовищі. Розглянуто теоретичні і практичні аспекти формування цінностей здорового способу життя у студентської молоді в процесі фізичного виховання.
Метою роботи є дослідження теоретичних і практичних аспектів формування цінностей здорового способу життя студентів засобами фізичного виховання.
Під час дослідження використовувалися такі методи: теоретичний аналіз та узагальнення наукової літератури, педагогічні спостереження, опитування (анкетування).
Результати дослідження. Проаналізовано форми та методи навчально-виховної роботи стосовно реалізації принципів здорового способу життя, обґрунтовано його значення для збереження і зміцнення здоров’я молоді. Визначено основні компоненти та узагальнено систему чинників, які перешкоджають формуванню цінностей здорового способу життя.
Проведений аналіз свідчить, що реалізація інноваційних підходів у сфері фізичної культури на основі урахування потреб студентської молоді є важливою передумовою підвищення мотивації до занять фізичними вправами, дотримання здорового способу життя, формування здоров’язберігаючої компетентності.
Висновки. Проведене дослідження дозволяє стверджувати, що формування цінностей здорового способу життя студентської молоді в умовах вищого навчального закладу – це насамперед формування систем відповідних цінностей, орієнтацій і установок, активної життєвої позиції майбутніх фахівців, їх позитивної мотивації до саморозвитку та самовдосконалення, прийняття відповідальності за власне здоров’я і самореалізацію в соціальному і професійному середовищі.
About the conference ICAAM 2022. Preface
Authors:   Department of Mathematics, Bahcesehir University, Ashyralyev A. ,   Peoples’ Friendship University of Russia (RUDN University),   Institute of Mathematics and Mathematical Modeling, Sadybekov M. ,   Institute of Mathematics and Mathematical Modeling
Published: July 2023

This issue is a collection of 13 selected papers. These papers are presented at the Sixth International Conference on Analysis and Applied Mathematics (ICAAM 2022) organized by Bahcesehir University, Turkey, Institute of Mathematics and Mathematical Modelling, Kazakhstan, and Analysis & PDE Center, Ghent University, Belgium. The meeting was held on October 31 – November 6, 2022, in Antalya, Turkey. The conference is organized biannually. Previous conferences were held in Gumushane, Turkey in 2012; in Shymkent, Kazakhstan in 2014; in Almaty, Kazakhstan in 2016; in Cyprus, Turkey in 2018 and 2020; in Antalya, Turkey in 2022. The proceedings of ICAAM 2012, ICAAM 2014, ICAAM 2016, ICAAM 2018, and ICAAM 2020 were published in AIP Conference Proceedings (American Institute of Physics) and in some rating scientific journals. Proceedings of ICAAM 2022 will be published in the world-renowned AIP Conference Proceeding Series. The main aim of the International Conferences on Analysis and Applied Mathematics (ICAAM) is to bring mathematicians working in the area of analysis and applied mathematics together to share new trends of applications of mathematics. In mathematics, the developments in the field of applied mathematics open new research areas in analysis and vice versa. That is why, we planned to found the conference series to provide a forum for researches and scientists to communicate their recent developments and to present their original results in various fields of analysis and applied mathematics. This issue presents papers by authors from different countries: Azerbaijan, Iraq, Russian Federation, Cyprus, Turkey, Kazakhstan, Turkmenistan, Uzbekistan, Kyrgyzstan. Especially we are pleased with the fact that many articles are written by co-authors who work in different countries. We are confident that such international integration provides an opportunity for a significant increase in the quality and quantity of scientific publications. Special thanks to Charyyar Ashyralyyev (Turkey) for their valuable assistance. Finally, but not least, we would like to thank the Editorial board of the «Bulletin of the Karaganda University. Mathematics series», who kindly provided an opportunity for the formation of this special issue.
A family of definite integrals involving Legendre’s polynomials
Authors: Qureshi M.I. , Malik S.H. , Ahmad D.
Published: July 2023

The main objective of this article is to provide the analytical solutions (not previously found and not available in the literature) of some problems related with definite integrals integrands of which are the products of the derivatives of Legendre’s polynomials of first kind having different order, with the help of some derivatives of Legendre’s polynomials of first kind Pn(x), Rodrigues formula, Leibnitz’s generalized rule for successive integration by parts and certain values of successive differential coefficients of (x2-1)r at x = ±1.
Boundary value problems of integrodifferential equations under boundary conditions taking into account physical nonlinearity
Authors: Seitmuratov A.Zh. , Medeubaev N.K. , Kozhoshov T.T. , Medetbekov B.R.
Published: July 2023

When solving integrodifferential equations under boundary conditions, taking into account physical nonlinearity, a broad class of boundary-value problems of oscillations arises associated with various boundary conditions at the edges of a flat element. When taking into account non-stationary external influences, the main parameters is the frequency of natural vibrations of a flat component, taking into account temperature, prestressing, and other factors. The study of such problems, taking into account complicating factors, reduces to solving rather complex problems. The difficulty of solving these problems is due to both the type of equations and the variety. We analyze the results of previous works on the boundary problems of vibrations of plane elements. Possible boundary conditions at the edges of a flat element and the necessary initial conditions for solving particular problems of self-oscillation and forced vibrations, and other problems are considered. The set of equations, boundaries, and initial conditions make it possible to formulate and solve various boundary value problems of vibrations for a flat element. The oscillation equations for a flat element in the form of a plate given in this paper contain viscoelastic operators that describe the viscous behavior of the materials of a flat component. In studying oscillations and wave processes, it is advisable to take the kernels of viscoelastic operators regularly, since only such operators describe instantaneous elasticity and then viscous flow.
On one approximate solution of a nonlocal boundary value problem for the Benjamin-Bona-Mahony equation
Authors: Manat A.M. , Orumbayeva N.T.
Published: July 2023

The paper investigates a non-local boundary value problem for the Benjamin-Bona-Mahony equation. This equation is a nonlinear pseudoparabolic equation of the third order with a mixed derivative. To find a solution to this problem, an algorithm for finding an approximate solution is proposed. Sufficient conditions for the feasibility and convergence of the proposed algorithm are established, as well as the existence of an isolated solution of a non-local boundary value problem for a nonlinear equation. Estimates are obtained between the exact and approximate solution of this problem.
Compactness of Commutators for Riesz Potential on Local Morrey-type spaces
Authors: Matin D.T. , Akhazhanov T.B. , Adilkhanov A.
Published: July 2023

The paper considers Morrey-type local spaces from LMpθw The main work is the proof of the commutator compactness theorem for the Riesz potential [b,Iα] in local Morrey-type spaces from LMpθw1 to LMpθw2. We also give new sufficient conditions for the commutator to be bounded for the Riesz potential [b,Iα] in local Morrey-type spaces from LMpθw1 to LMpθw2. In the proof of the commutator compactness theorem for the Riesz potential, we essentially use the boundedness condition for the commutator for the Riesz potential [b,Iα] in local Morrey-type spaces LMpθw, and use the sufficient conditions from the theorem of precompactness of sets in local spaces of Morrey type LMpθw. In the course of proving the commutator compactness theorem for the Riesz potential, we prove lemmas for the commutator ball for the Riesz potential [b,Iα]. Similar results were obtained for global Morrey-type spaces GMpθw and for generalized Morrey spaces Mpw.
RENORMALIZED GROUND STATE ALPHA DECAY OF 212Po
Authors:   Instituto de Física Rosario (CONICET-UNR) Esmeralda y Ocampo, S2000EZP Rosario, Argentina  Departamento de Física FCEIA (UNR) Av. Pellegrini 250, S2000BTP Rosario, Argentina   Instituto de Estudios Nucleares y Radiaciones Ionizantes (UNR), Riobamba y Berutti, S2000EKA Rosario, Argentina, Dassie A.C. , Id Betan R. M. ,   Instituto de Física Rosario (CONICET-UNR) Esmeralda y Ocampo, S2000EZP Rosario, Argentina  Departamento de Física FCEIA (UNR) Av. Pellegrini 250, S2000BTP Rosario, Argentina  Instituto de Estudios Nucleares y Radiaciones Ionizantes (UNR), Riobamba y Berutti, S2000EKA Rosario, Argentina
Published: July 2023

In the present work, we use the complex-energy shell model formalism to describe the alpha decay of the 212Po nucleus. Single-particle bases constructed from Woods-Saxon potentials are used to build many-body basis. Spin-isospinGaussian effective interaction between all pairs of nucleons is considered. Four-body spectroscopic factor and single-particle width are calculated. The stability of the spectroscopic factor renormalization protocol is demonstrated, thus ensuring its physical significance, and its influence on the calculated alpha decay is presented. It is observed that the renormalization modifies the calculated half-life by∼40 %, which is a value three times larger than the experimental. Still, without appealing to any cluster structure from the beginning, i.e., all calculations were carried out using single nucleon degree of freedom.
EFFECT OF AQUEOUS EXTRACTS OF Phyllanthus sellowianusON THE VISCOELASTICPROPERTIES OF HUMAN RED BLOOD CELLS:IN VITRO ANTIDIABETIC ACTIVITY
Authors:   Fac. Cs. Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario – Suipacha 535 – (2000) Rosario – Argentina, Mascaro Grosso H. , Buszniez P. ,   Fac. Cs. Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario – Suipacha 535 – (2000) Rosario – Argentina, Castellini H.V. ,   Fac. Cs. Exactas, Ingeniería y Agrimensura – Universidad Nacional de Rosario – Pellegrini 250 – (2000) Rosario – Argentina, Riquelme B.D. ,   Fac. Cs. Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario – Suipacha 535 – (2000) Rosario – Argentina  Grupo de Física Biomédica – IFIR (CONICET-UNR) – Bv. 27 de febrero 210 bis – (2000) Rosario – Argentina
Published: July 2023

Phyllanthus sellowianusMüll (Klotzch) Arg. is a native plant used for diabetes treatment. It is currently of interest to evaluate its activity on the mechanical properties of human red blood cells to elucidate its mechanism of action as an antidiabetic. For this, aqueous extracts were prepared by various extractive techniques. Using the Erythrocyte Rheo-meter, the in Vitro effect on the viscoelastic parameters of glycated human red blood cells, as occurs by hyperglycemia in diabetes, was evaluated. The results obtained from the treatment with the extracts show that they affect erythrocyte viscoelasticity and can reverse the glycation effects.
Application of modern technologies to improve the quality of sausage products
Authors: Kryzhova Yuliia , Slobodianiuk Nataliia , Moskalenko Ihor
Published: July 2023

. The production of sausages without the use of phosphates and sodium nitrite improves the quality and safety of the product, meeting the demand of consumers for natural and healthy food products. The purpose of the study was to investigate various technological aspects of sausage products that would improve their quality indicators, be attractive to the consumer, and have a positive impact on human health. Organoleptic qualities were evaluated by the appearance, consistency, type of minced meat on the cut, smell, taste; protein content – by Kjeldahl method; moisture content – by drying the suspension in a drying cabinet at a temperature of 103 ± 2°C to a constant mass; fat content – by extraction and weight Soxhlet method; moisture retention capacity – by centrifugation; penetration stress – by recalculation of penetration using a needle indenter; output of the finished product – by weighing before and after heat treatment. The replacement of sodium nitrite with organic nitrite based on chard powder was studied together with a bacterial culture that, as a result of interaction, produces nitrate reductase and reduces nitrate to nitrite (samples 1, 2), in samples 3 and 4, chard powder was replaced with beet juice. All samples were pink in colour. Replacing phosphates with amylopectin starch gave the developed sausages an elastic and juicy consistency, increased the moisture retention capacity by 4.6%-6% compared to the control sample, and penetration stress by 31%-53%. The use of sous-vide technology provided the developed sausage samples with a more pronounced good taste of each recipe ingredient separately, a delicate, elastic consistency, a uniform colour on the cut, and a higher yield by 1.8%- 3.3%. Replacing fatty raw materials with dietary ones, and cooking sausages in heat-resistant bags with vacuuming provided an increase in protein by 8.7%-16.7% and a reduction in fat by almost two times. The practical value of the study was to obtain a dietary product that meets the needs of modern people in a healthy diet
Morphometric characteristics of Ukrainian steppe bees depending on the method of controlled queen mating
Authors: Salyuk Oleksandr
Published: July 2023

Bee breed is an important factor in determining bee family development and productivity, as it affects honey production, disease resistance, climate adaptation, and bee behaviour characteristics. The purpose of the study was to establish the relationship between the methods of mating queens and the morphological characteristics of bees of the Ukrainian steppe breed and the productive indicators of bee colonies. To conduct the research, 43 bee colonies with queen sisters of the Ukrainian steppe breed mated by different methods of natural mating were established in the Vinnytsia oblast. According to the results of mating, there were 22 queen bees in the control group, and 21 queen bees in the experimental group. The queens of the first control group mated in a normal natural way without any restrictions. The queen bees of the experimental group mated under time and space control. Based on the results of the research, the relationship between the integrity of the colony and its morphological features and productive indicators was established. Thus, experimental families have different degrees of belonging to the Ukrainian steppe breed, control – 59% and experimental – 87.2% (p < 0.001). According to the cubital index, the advantage was 8.2% (p < 0.001) in favour of the experimental group. The best family integrity on the hantel index was observed in families in which queens were mated in a controlled time and space, with a difference of 3.32% (p < 0.001). In the control group, where uncontrolled mating of queens was performed, more bees were found for discoid displacement with an excess of the standard indicator for the breed. Families in the experimental group were stronger by 14.5% (p < 0.001) compared to the control group. They provided 41.9% more honey, built 22.1% more honeycombs (p < 0.01), and the need for Kandy feeding was 31.8% less (p < 0.001). In addition, the bees of the experimental group had pronounced hygienic behaviour and required less labour costs. The practical significance of the study lies in the possibility of establishing patterns of action of factors on a particular breed and confirms the need to implement breeding programmes in beekeeping
Features of the course of coronary artery disease in the post-COVID period
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Derisheva D.A. , Yakhontov D.A. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Dunicheva O.V. ,   Novosibirsk Regional Clinical Cardiology Dispensary, Novosibirsk, Russia
Published: July 2023

Introduction. The coronavirus disease 2019 (COVID-19) pandemic has been going on for more than two years and is significantly affecting routine clinical practice. Despite the numerous publications on heart damage in the acute phase of COVID-19, there is not enough data regarding the dynamics of cardiovascular system condition in coronary artery disease (CAD) patients after the infection caused by SARS-CoV-2. The influence of the long-term consequences of the disease on cardiovascular system condition of patients who have had infection requires careful study. Aim. To assess the clinical and laboratory picture and coronary lesion nature in CAD patients with mild or moderate course of COVID-19 infection after at least 12 weeks. Materials and methods. The analysis of clinical, laboratory parameters and coronary angiography of 118 CAD patients aged 46–67 years (mean age 60.2 ± 6.1 years) after a serologically confirmed SARS-CoV-2 infection at the lapse of 12 weeks was carried out. The patients were divided into 2 groups: group 1 included 60 patients with a mild COVID-19, group 2 included 58 patients with a moderate COVID-19 course. Results. CAD patients with a moderate course of COVID-19 in the acute period had higher values of office blood pressure, higher incidence of uncontrolled arterial hypertension, major multivessel lesions of coronary arteries and lesions of the main vessels than CAD patients with mild COVID-19. When comparing echocardiographic parameters in patients with moderate COVID-19, the lower parameters of the left ventricular ejection fraction were found which is quite consistent with the higher NT-proBNP values in these patients. Conclusion. CAD patients, who have had moderate COVID-19 in the acute phase of infectious process, constitute a special risk group for a subsequent more severe course of the underlying disease.
Assessment of the quality of life in non-operated young patients after subarachnoid hemorrhage
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Petrova Е.V. , Popova Т.F. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Gribacheva I.A. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Shchepankevich L.A. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Denisova О.А. ,   Novosibirsk City Clinical Hospital No. 1, Novosibirsk, Russia
Published: July 2023

Introduction. Currently, to determine the level of social and economic well-being of individual members of society or social groups, the concept of “quality of life” is increasingly being used which is proposed to be considered as the degree of comfort of an individual, both within himself and within his society. This allows you to identify factors that either improve life or worsen it. That is why the study of quality of life, as an integral characteristic of the physical, psychological, emotional and social state of a patient, based on his subjective perception, is stated on three components: multidimensionality, which allows to differentially determine the impact of disease and treatment on the patient’s condition; variability in time depending on the patient’s condition; participation of a patient in the assessment of his condition, which is the most valuable indicator of his general state. Aim. Assessment of the quality of life in non-operated young patients after subarachnoid hemorrhage (SAH). Materials and methods. The study included 165 patients with SAH (76 men, 89 women; mean age 48.82 ± 5.29 years). All patients underwent a comprehensive examination, which included the collection of complaints and anamnestic data with the identification of vascular risk factors, computed tomography (CT) and CT angiography, lumbar puncture, transcranial dopplerography, ultrasound examination of the main vessels of the head and neck, heart and abdominal organs. The vegetative state was assessed according to the A.M. Vein’s Questionnaire of Autonomic Disorders, general and mental fatigue – according to the Multidimensional Fatigue Inventory (MFI-20), cognitive ability – using a test battery, psycho-emotional status – according to the Spielberger’s State-Trait Anxiety Inventory, depressive disorders – according to the Hamilton Depression Rating Scale. Quality of life was assessed using the Nottingham Health Profile. Results. The decrease in the quality of life as a result of SAH in young people depended on the level of stigmatization and was determined by the severity of psycho-vegetative disorders, symptomatic general and mental fatigue, state and trait anxiety, depressive disorders and cognitive impairments. Conclusion. It is the integral assessment of quality of life that is the fundamental vector in the prospective observation of the examined patients, and, despite the absence of focal neurological symptoms and signs in most patients, there is a need to refer them to rehabilitation programs.
Study of the antibacterial properties of new caffeine derivatives against opportunistic pathogenic bacteria in vitro
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Bondareva E.A. , Reshetnikov D.V. ,   N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Novosibirsk, Russia, Burova L.G. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Patrushev S.S. ,   N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Novosibirsk, Russia, Zakharova L.N. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Evstropov A.N. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Schults E.E. ,   N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Novosibirsk, Russia
Published: July 2023

Introduction. The resistance of microbes to many classes of antimicrobial drugs is a global threat to human health and necessitates the search for new compounds with antimicrobial activity, with low toxicity and a potentially wide range of biological activity. Aim. To study in vitro the ability of new xanthine derivatives (caffeine, 1-butyltheobromine and 7-butyltheophylline) to inhibit growth Staphylococcus (S.) aureus, Bacillus (B.) cereus, Escherichia (E.) coli and Pseudomonas (P.) aeruginosa. Materials and methods. The antibacterial activity of xanthine derivatives synthesized in the Laboratory of Medicinal Chemistry of the N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry was studied in vitro using serial dilutions in a liquid nutrient medium against S. aureus, B. cereus, E. coli and P. aeruginosa cultures. Results. Three substances, including the starting material – caffeine and 7-butyltheophylline, did not show antibacterial properties against test microbes. All xanthine derivatives studied did not inhibit the growth of E. coli and P. aeruginosa; 9 compounds containing fragments of amino acid esters or an acetylene substituent in the position of the C-8 xanthine backbone showed antibacterial activity against S. aureus and (or) B. cereus. Conclusion. When studying the ability of natural xanthine caffeine and 12 of its derivatives to inhibit the growth of cultures of opportunistic bacteria, antibacterial properties against S. aureus and B. cereus were revealed in a number of amino acid derivatives. The best effect was shown by compounds containing fragments of alpha- and beta-amino acid esters (L-valine and beta-phenyl-beta-alanine), which determines the prospects for further research.
Quality of life assessment in patients with Hodgkin’s lymphoma at disease onset and after chemoradiotherapy
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Shebunyaeva Ya.Yu. ,   State Novosibirsk Regional Clinical Hospital, Novosibirsk, Russia, Nechunaeva I.N. ,   City Clinical Hospital No. 2, Novosibirsk, Russia, Vorontsova E.V. ,   State Novosibirsk Regional Clinical Hospital, Novosibirsk, Russia, Voytko M.S. ,   Novosibirsk State Medical University, Novosibirsk, Russia, Pospelova T.I. ,   Novosibirsk State Medical University, Novosibirsk, Russia
Published: July 2023

Introduction. An advance in understanding the biology of Hodgkin’s lymphoma (HL) and improved approaches to anticancer therapy of HL allowed increasing the survival of patients at all stages of the disease. Thus, the 5-year overall survival is more than 85% even in HL patients with III–IV stages. However, early complications and long-term effects of combined chemoradiotherapy remain an urgent problem, reducing the quality of life of patients. Aim. To assess the quality of life of patients with HL in different periods of the disease: at the time of diagnosis of the tumor process and after multiagent chemotherapy programs. Materials and methods. The study included 46 patients with newly diagnosed HL, hospitalized in the Hematology Departments of the City Clinical Hospital No. 2 and the Novosibirsk Regional Clinical Hospital. The control group was represented by 46 apparently healthy people without a tumor process or exacerbation of chronic diseases. The SF-36 Health Survey was used as a tool for assessing the quality of life. Results. The quality of life of patients was significantly higher in patients at onset of the disease than after specific anticancer therapy. Compared with the control group, in patients with HL, both before the start of treatment and after chemoradiotherapy, a deterioration in the physical condition affecting daily activities was noted. Also, with an increase in the in the number of courses of anticancer therapy, the emotional and physical health of patients with HL worsened significantly, and the intensity of pain syndrome was higher in patients with advanced stages of the disease. Conclusion. Currently, the assessment of the quality of life in patients with hematologic malignancies at onset of the disease and after anticancer therapy can help achieve optimal therapy results while maintaining a high level of quality of life.
Spatial Distribution of Tuberculosis in the Western Region of Java Island, Indonesia
Authors: Purnama Tri Bayu , Kamigaki Taro , Minsarnawati Minsarnawati , Oshitani Hitoshi
Published: July 2023

Objective: This study aimed to map the spatiotemporal hotspots of tuberculosis (TB) prevalence distribution in the Western Region of Java Island. Material and Methods: To investigate the spatiotemporal pattern of TB prevalence, we standardized TB prevalence by year, with the percentile of TB prevalence being clustered with natural Jenks breaks optimization. To estimate the continuous geographical distribution of TB prevalence within each district, we performed inverse distance weighting (IDW) methods for spatial interpolation. We calculated the expected number of TB cases per 1 km2 grid cell in the aim of detecting TB prevalence hotspots. Results: The overall mean prevalence of newly reported TB cases was 73.2 cases per 100,000. The TB prevalence in West Java province, Banten province, and Jakarta province were 71.7, 69.7 and 85.8 per 100,000, respectively. High prevalence grid cells along the coast in the north, and low cells in West Java province; except nearby Bandung city where most areas are mountainous, were detected. Hotspots area was mostly found in either West Java province or Banten province; only 1 hotspot was detected in Jakarta province. Conclusion: Several hotspots were observed, not only in town administration areas but also in lower population density areas in West Java province. Raster grid cells with high prevalence were identified along the coastal area in the northern study area.
COLLABORATIVE SNOWBALL THROWING DALAM PERTEMUAN PENINGKATAN KEMAMPUAN KELUARGA PKH TENTANG PENGASUHAN
Authors: Nurul Fatimah Sarah , Susilawati Susilawati , Syaodih Ernalia Lia
Published: July 2023

Collaborative Snowball Throwing merupakan teknologi hasil rekayasa di dalam kegiatan Pertemuan Peningkatan Kemampuan Keluarga (P2K2) Program Keluarga Harapan (PKH) dalam modul perlindungan anak dengan model pembelajaran kooperatif dalam penguatan kapasitas pengasuhan anak yang melibatkan tim kerja masyarakat. Penelitian ini bertujuan untuk menganalisis dan mengoptimalkan kegiatan P2K2 dengan melibatkan masyarakat. Penelitian ini difokuskan di Kelurahan Sukabungah, Kecamatan Sukajadi, Kota Bandung. Penelitian ini dilaksanakan dengan menggunakan metode kualitatif dengan rancangan penelitian tindakan (action research). Hasil penelitian menunjukan bahwa kegiatan P2K2 yang menyediakan pembelajaran praktis di bidang pendidikan, perlindungan anak, ekonomi, kesehatan serta lansia dan disabilitas bagi keluarga penerima manfaat selama ini masih belum berjalan optimal dikarenakan beberapa alasan sehingga belum memberikan dampak terhadap pengasuhan yang baik untuk mampu memutus anak agar tidak beraktivitas di jalanan. Sehingga hasil dari implementasi rekayasa teknologi Collaborative Snowball Throwing dalam P2K2 mampu mengoptimalkan proses pembelajaran di bidang pengasuhan dalam P2K2 karena Keluarga Penerima Manfaat  merasa dilibatkan dalam proses pembelajaran Melalui implementasi rekayasa teknologi dengan dukungan lingkungan sekitar.
EFEKTIVITAS PERTEMUAN PENINGKATAN KEMAMPUAN KELUARGA (P2K2) PROGRAM KELUARGA HARAPAN (PKH) MASA PANDEMI COVID-19 DI KECAMATAN SARANG KABUPATEN REMBANG
Authors: Pribowo Pribowo , Pratiwi Inna Justitia
Published: July 2023

Pelaksanaan Pertemuan Peningkatan Kemampuan Keluarga belum dapat dilaksanakan secara maksimal karena pandemi Covid-19. Pertemuan dilaksanakan dengan memanfaatkan teknologi whatsapp, zoom meeting dan google meet, hal tersebut membuat pendamping tidak dapat memantau perkembangan penerima manfaat Program Keluarga Harapan sesuai dengan tujuan pertemuan. Tujuan penelitian ini untuk mendapatkan gambaran empiris dan menganalisis tentang 1) Karaktristik keluarga penerima manfaat Program Keluarga Harapan di Kecamatan Sarang, 2) Ketepatan penentuan waktu, 3) Ketepatan penentuan pilihan, 4) Ketepatan tujuan, 5) Ketepatan sasaran P2K2 PKH masa pandemi Covid-19 di Kecamatan Sarang. Penelitian ini menggunakan pendekatan kuantitatif dengan metode deskriptif. Sumber data yang digunakan adalah sumber data primer dan sekunder. Alat ukut penelitian ini menggunakan skala likert dengan uji validitas muka dan uji reliabilitas alpha cronbach dengan bantuan aplikasi SPSS Versi
20. Teknik pengumpulan data menggunakan kuesioner dan studi dokumentasi. Teknik analisis data menggunakan analisis statistik deskriptif. Hasil penelitian menunjukkan efektivitas P2K2 PKH masa pandemi Covid-19 di Kecamatan Sarang berada pada kategori “tinggi” dengan perolehan skor aktual sebesar 12.083 dari skor ideal 15.132. Hal tersebut menunjukkan bahwa Efektivitas Pertemuan Peningkatan Kemampuan Keluarga sudah berjalan efektif. Berdasarkan hasil penelitian, masalah yang ditemukan di lapangan yaitu kurangnya pengetahuan dan keterampilan pendamping dalam menentukan pilihan media dan alat yang digunakan dalam pertemuan sehingga menyebabkan penerima manfaat kurang menyerap informasi yang disampaikan. Berdasarkan permasalahan tersebut, peneliti mengusulkan Program Peningkatan Kemampuan Pemanfaatan Teknologi Pendamping Program Keluarga Harapan Kecamatan Sarang
KINERJA PENDAMPING PROGRAM KELUARGA HARAPAN (PKH) DALAM PERTEMUAN PENINGKATAN KEMAMPUAN KELUARGA (P2K2) DI KECAMATAN BOJONGSOANG KABUPATEN BANDUNG
Authors: Depari Reiki Polo Brice Depari , Riasih Teta , Rosilawati Rosilawati
Published: July 2023

Kinerja Pendamping Program Keluarga Harapan adalah penentu keberhasilan program keluarga harapan dalam meningkatkan taraf hidup keluarga penerima manfaat dalam mengakses pelayanan Kesehatan, Pendidikan, dan meningkatkan kesejahteraan sosial. Penelitian ini bertujuan untuk menggambarkan secara empiris gambaran kinerja pendamping program keluarga harapan di Kecamatan Bojongsoang, Kabupaten Bandung berdasarkan karakteristik Keluarga Penerima Manfaat, Aspek Kualitas Kerja, Ketepatan Waktu, Kemampuan, dan Komunikasi. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif. Sumber data yang digunakan dalam penelitian ini adalah sumber data primer dan sumber data sekunder. Teknik penarikan sampel dalam penelitian ini menggunakan area sampling (cluster). Teknik pengumpulan data yang digunakan adalah angket/kuesioner dan studi dokumentasi. Alat ukur yang digunakan dalam penelitian ini adalah Rating Scale, serta uji validitas muka (face validity). Hasil penelitian menunjukkan bahwa kinerja Pendamping Program Keluarga Harapan di Kecamatan Bojongsoang termasuk pada kategori sangat baik pada setiap aspek. Namun perlu adanya peningkatan Pengetahuan, Kemampuan, dan Komunikasi bagi pendamping PKH di Kecamatan Bojongsoang. Berdasarkan pada hal tersebut, peneliti mengusulkan program “Penguatan Kapasitas bagi Pendamping Program Keluarga Harapan di Kecamatan Bojongsoang” yang bertujuan untuk meningkatkan kinerja pendamping program keluarga harapan di Kecamatan Bojongsoang Kabupaten Bandung.
PERAN PEKERJA SOSIAL PADA DISABILITAS MENTAL MELALUI BIMBINGAN VOKASIONAL DI RUMAH PELAYANAN SOSIAL DISABILITAS MENTAL (RPSDM) “MARTANI” CILACAP
Authors: Galih Fajar Fadillah Galih , Aini Innayah Nur
Published: July 2023

Penelitian ini bertujuan untuk mendeskripsikan bagaimana peran pekerja sosial sebagai pemungkin (enabler) dalam pemulihan keberfungsian sosial penerima manfaat melalui bimbingan vokasional. Metode penelitian yang digunakan adalah penelitian kualitatif dengan pendekatan studi kasus yang merupakan metode yang digunakan untuk menggambarkan informasi yang lebih lengkap, sehingga pemahaman yang dihasilkan terhadap suatu kasus yang dipelajari lebih mendalam. Penelitian ini menggunakan penentuan subjek dengan teknik purposive sampling yaitu dua orang pekerja sosial. Teknik pengumpulan data dilakukan dengan wawancara, observasi, serta dokumentasi. Hasil penelitian menunjukkan bahwa peran pekerja sosial sebagai pemungkin (enabler) dalam pemulihan keberfungsian sosial penerima manfaat melalui bimbingan vokasional yaitu pada tahapan produksi dimana pekerja sosial memfasilitasi pendidikan dan memberikan teknik group work untuk kebutuhan interaksi sosial penerima manfaat. Kemudian, pada tahapan pasca produksi pekerja sosial berperan memelihara relasi dengan stakeholder, membuat inovasi warung sosial, mengikutsertakan penerima manfaat dalam kegiatan vokasional diluar lembaga sebagai sarana penjualan hasil karya dan untuk membiasakan mereka beradaptasi dengan lingkungan masyarakat yang lebih luas. Serta, melakukan penyaluran kerja terhadap penerima manfaat yang sudah mampu untuk dipekerjakan.
Bimbingan Kelompok dalam Setting Kegiatan Learning and Camping untuk Membangun Penyesuaian Diri Mahasiswa Baru
Authors: Adiansyah Adiansyah , Karamoy Yurike Kinanthy , Wulandari Dwi Gusti , Ridayana Weny
Published: July 2023

The first year of college is a difficult time for new students. In addition to orientation activities, other activities are also possible so that students are able to adjust to academic life in higher education through student organizations, one of which is learning and camping  activities organized by HMPS Study Program. The research was conducted on  learning and camping activities with qualitative methods with  the  aim  of exploring information related to how group guidance in setting learning and camping activities to build new student adjustment in the BKI IAIN Pontianak study program with the hope that it can be an additional reference in enriching references in the field of counseling guidance.  Data collection  maximizes in-depth interviews and participant observation and maximizes documentation for BKI students  from 2019/  2020 to 2022/2023. As a result, after participating  in learning and camping  activities, new students who initially felt inferior, anxious and even stressed little by little were able to adjust to learning patterns and life in the college environment so that they could show positive results in both academic and non-academic fields. _____________________________________________________________ Tahun pertama perkuliahan sebagai masa yang sulit bagi mahasiswa baru. Mahasiswa baru diberikan kegiatan orientasi sebagai upaya untuk memperkenalkan sistem pembelajaran diperguruan tinggi. Selain kegiatan orientasi, kegiatan lain juga dimungkinkan dapat dilakukan agar mahasiswa mampu menyesuaikan diri dengan kehidupan akademik di perguruan tinggi melalui organisasi kemahasiswaan salah satunya kegiatan learning and camping yang diselenggarakan oleh HMPS Prodi. Penelitian dilakukan pada kegiatan learning and camping dengan metode kualitatif dengan tujuan menggali informasi terkait bagaimana bimbingan kelompok dalam setting kegiatan learning and camping untuk membangun penyesuaian diri mahasiswa baru pada prodi BKI IAIN Pontianak dengan harapan dapat menjadi tambahan rujukan dalam memperkaya referensi bidang bimbingan konseling. Pengumpulan data memaksimalkan wawancara mendalam atau in-depth interview dan participant observation serta memaksimalkan dokumentasi pada mahasiswa BKI angkatan 2019/2020 s/d 2022/2023. Alhasil setelah mengikuti kegiatan learning and camping mahasiswa baru yang awalnya merasa minder, cemas bahkan stres sedikit demi sedikit mampu menyesuaikan diri dengan pola pembelajaran dan kehidupan di lingkungan perguruan tinggi sehingga dapat menunjukkan hasil yang positif baik pada bidang akademik maupun non akademik.
Konseling Musik untuk Mereduksi Kecemasan Berbicara di Depan Kelas Pada Siswa SMPN 19 Jambi
Authors: Alfadhilah Amaliah , Nelyahardi Nelyahardi , Ferdiansyah Muhammad
Published: July 2023

Anxiety about speaking in front of the class can be said to be an obstacle in the student learning process. One way to reduce it is to use music therapy. The purpose of this study was to reveal the effectiveness of using music therapy to reduce students' anxiety about speaking in front of the class. This research uses Quasi Experimental Design or quasi-experimental research using Pretest Posttest Nonequivalent Control Group Design. The population in this study were students in class VIII A & VIII B totaling 59 people. The sample in this study was 30 students who were taken by purposive sampling technique. The results of this study indicate that the anxiety of students speaking in front of the class in the experimental class for the pretest is 1546 and for the posttest is 1245. As for the control class, that is for the pretest it is 1454 and for the posttest it is 1340. Based on the results of the t-test calculation, Tcount is obtained which is equal to -2.553. The value of Ttable with Sig. (2-tailed) 0.05, which is 2.160. The hypothesis is accepted or music therapy is effective in reducing students' anxiety about speaking in front of class VIII A SMP Negeri 19 Jambi City. _____________________________________________________________ Kecemasan berbicara di depan kelas dapat dikatakan sebagai penghambat dalam proses belajar siswa. Salah satu cara untuk menguranginya ialah menggunakan terapi musik. Tujuan penelitian ini mengungkapkan efektivitas penggunaan terapi musik untuk mereduksi kecemasan siswa berbicara di depan kelas. Penelitian ini menggunakan jenis Quasi Experimental Design atau penelitian eksperimen semu dengan menggunakan Pretest Posttest Nonequivalent Control Group Design. Populasi pada penelitian ini ialah siswa kelas VIII A & VIII B berjumlah 59 orang. Sampel pada penelitian ini berjumlah 30 orang siswa yang diambil dengan teknik purposive sampling. Hasil penelitian ini menunjukkan bahwa kecamasan siswa berbicara di depan kelas pada kelas eksperimen untuk pretest yakni sebesar 1546 dan untuk posttest sebesar 1245. Sedangkan untuk kelas kontrol yakni untuk pretest sebesar 1454 dan untuk posttest 1340. Berdasarkan hasil perhitungan t-test di peroleh Thitung yaitu sebesar -2,553. Adapun nilai dari Ttabel dengan nilai Sig. (2-tailed) 0,05 yaitu sebesar 2,160. Hipotesis dinyatakan diterima atau terapi musik efektif untuk mereduksi kecemasan siswa berbicara di depan kelas VIII A SMP Negeri 19 Kota Jambi.