bluuebunny/crossref_metadata_2025 huggingface dataset:
The Changing Perceptions of Death in Annuitterra Articulated Skeleton Set
Authors: Wiguna Iqbal Prabawa , Hernawan Abbyzar Raffi , Yuningsih Cucu Retno , Widyaevan Dea Aulia , Mokhtar Mumtaz
Published: January 2025

This paper explores the topic of contemporary art that blends art, science, and design in unexpected and sometimes unsettling ways. One such example is one of the author’s projects; the Annuitterra skeleton set, which is both a unique work of art and a limited niche product. In the past, death was often a feared topic due to the uncertainty surrounding it. However, with advances in science and technology, our perception of death has shifted. The skeleton sets produced by Annuitterra are packaged as model kits that can be assembled by the audience. Through this process, people not only engage with animal skeletons but also learn about their anatomy. this skeleton sets series is used and analyzed to examine how this project commodifies the theme of death and makes it more accessible to the contemporary market through branding strategies, media partnerships, and collaborations. Ultimately, the investigation of the Annuitterra skeleton set reveals a changing perception of death in modern society. The enigma of death remains in this project, but our approach to it can be playful and bold to adapt to the continuously evolving complexities of contemporary art.
Keywords: contemporary art, Annuitterra, articulating skeleton, death theme
Spiritual Meanings and Symbols in Motifs of Batik Betawi
Authors: Woelandhary Ayoeningsih Dyah , Damayanti Nuning Y. , Sunarya Yan Yan , Adriati Ira
Published: January 2025

The history of batik is one of the archipelago’s craft products whose existence was born along with the history of human civilization. In its growth, batik in Java was closely associated with the nobility, royal/sultanate relatives, close to priyayi life and a symbol of feudalism. Motifs in batik are often associated with sacred symbols, have religious meanings as well as reflections of spirituality for people who believe in them. Spirituality is associated with religious activities and is seen as a reflection or form of religious appreciation, the depth of belief expressed generally in the form of worship. In the study of fine art, the reflection of spirituality is found in Betawi batik motifs. The reflection is also expressed in various visual elements, meanings and symbols and is lived as part of the reflection in the lives of the majority of Betawi ethnicity. The research method uses the theory of visual language, with a qualitative descriptive method, where the visuals found will be described descriptively, the meaning contained therein and the cultural background inherent in the visuals.
Keywords: Baritan, Betawi Batik Jakarta, meanings and symbols
Metacorpos ou uma biofilosofia proposta por François Dagognet: a propósito dos estudos sobre corpo na Educação Física Brasileira
Authors: Ribeiro Gisele Rosa , Peres Nélio Borges
Published: January 2025

François Dagognet, em sua obra “O Corpo” (2012) aborda concepções de corpo que influenciaram diretamente no modo de vida humano. A partir da percepção de um corpo apagado pela sociedade, o autor questionar a existência e o uso dos metacorpos no ocidente. Em um diálogo entre a Educação Física (brasileira) e a Filosofia, o corpo é um objeto investigado a partir da existência da dualidade corpo e mente presente na historiografia que analisamos de forma quanti-qualitativa que permitiu verificar que François Dagognet e sua percepção corporal não aparecem na Educação Física brasileira no período de 2017 a 2022 e mesmo assim apresentamos a obra como possível referência para a Educação Física.
Nacionalismo e revolução no terceiro mundo:as propostas anticoloniais de Guerreiro Ramos e Frantz Fanon
Authors: Silva José Victor Alves da
Published: January 2025

Esta pesquisa analisa as propostas de superação do colonialismo elaboradas pelo sociólogo e político brasileiro Alberto Guerreiro Ramos e pelo psiquiatra e filósofo martinicano-argelino Frantz Omar Fanon. Para isso, minhas fontes principais foram as produções teóricas desses autores na década de 1950 e início dos anos 1960. Através do método contextualista e da abordagem comparativa, investiguei como os autores conceberam a situação colonial de países do Terceiro Mundo, em especial do Brasil e da Argélia, na segunda metade do século XX. Comparando os dois intelectuais e militantes negros, pode se notar que existem semelhanças em suas teorias, mas também diferenças fundamentais, principalmente em suas trajetórias pessoais e posicionamentos políticos. Enquanto Guerreiro Ramos apostou em um programa estatal de desenvolvimento socioeconômico de viés popular, Frantz Fanon se dedicou a doutrinas revolucionárias que pregavam a contraviolência da luta armada e auto-organização como meios de transformação social.
O absurdo infamiliar:uma análise dos processos de subjetivação a partir de Albert Camus e da psicanálise freudiana
Authors: Campos Marcos Ferreira
Published: January 2025

O artigo visa discutir a filosofia de Albert Camus e a psicanálise freudiana. A teoria do absurdo de Camus, é uma lente a ser usada na leitura dos comportamentos culturais contemporâneos. Nesse ponto, percebe-se que aquilo que o filósofo mapeia como condição anormal da vida humana tem tomado lugar de estabilidade no campo psicossocial cotidiano. Albert Camus, nos lega a visão de felicidade pautada na liberdade, além da física, dos corpos. Uma liberdade transcendente em que se pode galgar o tempo da escolha e do juiz. A sociedade contemporânea com seus afetos mórbidos e líquidos oferta uma liberdade "absurda", que rouba do homem o caráter de condutor de sua própria vida. Sua problemática da revolta se mantém de uma maneira camuflada, ou seja, o homem revoltado dá lugar ao homem conformado, contudo sem perder a volatilidade do desejo-revolta pautada na teoria mítica de Sísifo e seu esforço eterno e inútil.
Effect of Sex, Locations and Seasons on Nutritional Status of Non-descript Free-range Scavenge Chicken of Assam, India
Authors: Islam R. , Mahanta J.D. , Begum K. , Rahman M. , Ali A.
Published: January 2025

Background: The inferior productivity of non-descript free-range scavenge chicken might be due to poor nutrition. Further, nutritional status of such chicken varied with seasons, locations etc. In the present study, nutritional status of indigenous free-range chicken was investigated in different seasons and in different agro-climatic zones of Assam to formulate nutritional strategies to optimize their production potential. Methods: Altogether, 160 chickens (80 males and 80 females) of 7 to 10 months of age were collected randomly from different agro-climatic zones viz. Lower Brahmaputra Valley Zone (LBVZ), Upper Brahmaputra Valley Zone (UBVZ), Central Brahmaputra Valley Zone (CBVZ) and North Bank Plain Zone (NBPZ) of Assam during different seasons viz. Pre-monsoon (PRM), Monsoon (MON), Post-monsoon (PTM) and Winter (WIN) seasons and were slaughtered and their crop contents were separated out for physical and chemical analysis to assess the nutritional status of them. Result: The grains and by-products were significantly (P less than 0.05) higher during PTM season. The green forages were significantly (P less than 0.05) higher in CBVZ than other zones. The DM contents was significantly (P less than 0.05) higher in PTM season than other seasons. The proportions of CP were significantly (P less than 0.05) higher during MON season. Both DM and CP contents were significantly (P less than 0.05) higher in LBVZ zone. It could be concluded that the scavenged feed resource base varied with seasons and locations and was alsodeficient in some major nutrients in different locations and seasons and hence could not be fulfil nutritional requirement of free-range chicken. Therefore, it is very imperative to provide strategic incremental feeds along with minerals to free-range chickens to improve their production potential.
Numerical estimation of parameters in mathematical models for pest control
Authors: Gonzálea Aguirre Juan Carlos , Jiménez Alegría María Fernanda
Published: January 2025

In this work we focused on the estimation of the parameters belonging to a mathematical model for the interaction between three species (plant, plague and bio control agent), with the goal to guaranty the survival of all them. A qualitative analysis of the model is carried out to show the dynamic of it. As well, the model is solved by using a numerical scheme based on multi step method. The obtained code is coupled with the Spux framework to estimate, by stochastic simulations, the unknown parameters of the model. Numerical results show that Spux gives a correct approximation of the parameters because the model simulations with the approximated parameters are in good agreement with the data.
Slow Fashion e sua relação com redes sociais
Authors: Silva Íris Malta , Ferroli Paulo Cesar Machado
Published: January 2025

With a focus on the UN's Sustainable Development Goals (SDGs) for 2030, specifically SDG 12: “Responsible Consumption and Production”, this article relates the connection between slow fashion and social media. It seeks to promote persuasive communication strategies and the impact of social media on consumer awareness, communication and behavior. Its general objective is to verify the relationship between the desires of consumers and brands in relation to sustainability, with aspects of economic, social and environmental influence. Finally, it presents design and marketing strategies for one of the paths to sustainability in fashion, with a socially just approach and low environmental impact.
Animals as symbols of heretics in Latin European literature and art from the 9th to the 16th century
Authors: Dobkowska-Kubacka Joanna
Published: January 2025

Medieval heresies, posing a threat and competition for the official Church mobilized it to counter-attack, which was reflected in the animal symbolism both in literature and in the visual arts. In the period from the 9th to the 16th century, heretics were most often symbolized by wolves (the phenomenon of heresy itself was also represented in the form of a wolf, whose hellish origins were to be seen in the flames surrounding it) and foxes. Both served also as symbols of Satan himself. They owed their anti-heretical meaning to the exegesis of biblical verses and comparisons taken from literature, especially patristic one. The problem of sects has been discussed in the writings since the beginnings of Christianity, and later polemicists have often been inspired by the works of old Christian writers. Given the traditional association of foxes and wolves with the realm of evil, their choice of symbols of heretics emphasized Satanic origin and the character of heresy. However, its purpose was also to emphasize the specific character traits attributed to apostates from the Church: rapacity and deceitfulness associated with these animals. A variant of this deceitfulness was species pietatis – “false piety” attributed to heretics and associated with the Bible’s motif of “sheepskin” hiding the evil intentions of false prophets. In art this “sheepskin” took the form of a habit in which foxes were often dressed. The phenomenon of merging the fox figures from the fables of Aesop and their adaptations and symbols of the fox taken from the Bible took place. Attributing a “fox cunning” to heretics served to discredit them in the eyes of the rest of society, and to warn against them, so it was largely instrumental. Especially in the Late Middle Ages there is a great convergence between the image of heretic in art and the psychological stereotype of heretic existing in literature, especially in preaching. Occasional sermons about heresy using a simplified and prepared for the anti-heretic campaign image of heretic did not go into details of doctrinal differences between followers of different sects, treating all heresy as one offence. Catholic art was obviously not interested in objectively reflecting beliefs or depicting the real rites of heretics, the stereotypical features of character and the role of enemies of Christianity and mankind attributed to them were sufficient. From this point of view, animal symbols, as a tool for fighting heresy, could prove highly effective.
The Tannhäuser Gate. Architecture in science fiction films of the second half of the 20th and the beginning of the 21st century as a component of utopian and dystopian projections of the future
Authors: Wąs Cezary
Published: January 2025

The films of science fiction genre from the second half of the 20th and early 21st century contained many visions of the future, which were at the same time a reflection on the achievements and deficiencies of modern times. In 1960s, cinematographic works were dominated by optimism and faith in the possibility of never-ending progress. The disappearance of political divisions between the blocs of states and the joint exploration of the cosmos was foreseen. The designers undertook cooperation with scientists, which manifested itself in showing cosmic constructions far exceeding the real technical capabilities. Starting from the 1970s, pessimism and the belief that the future will bring, above all, the intensification of negative phenomena of the present began to grow in films. Fears of the future were connected with indicating various possible defects and insoluble contradictions between them. When, therefore, some dystopian visions illustrated the threat of increase in crime, others depicted the future as saturated with state control mechanisms and the prevalence of surveillance. The fears shown on the screens were also aroused by the growth of large corporations, especially by their gaining political influence or staying outside the system of democracy. The authors of the films also presented their suspicions related to the creation of new types of weapons by corporations, the use of which might breach the current legal norms. Particular objections concerned research on biological weapons and the possible spread of lethal viruses. The development of robotics and research into artificial intelligence, which must have resulted in the appearance of androids and inevitable tensions in their relations with humans, also triggered fear. Another problem for film-makers has become hybrids that are a combination of people and electronic parts. Scriptwriters and directors likewise considered the development of genetic engineering, which led to the creation of mutant human beings. A number of film dystopias contemplated the possibility of the collapse of democratic systems and the development of authoritarian regimes in their place, often based on broad public support. This kind of dystopia also includes films presenting the consequences of contemporary hedonism and consumerism. The problem is, however, that works critical of these phenomena were themselves advertisements for attractive products.
Presencia de Dactylosoma sp. en ranas del género Telmatobius decomisadas en Lima, Perú
Authors: Manrique Miguel , Elias Roberto , Zúñiga Renato , Troiano Juan Carlos
Published: January 2025

El Perú es un país megadiverso y ocupa el tercer puesto en diversidad de anfibios; sin embargo, el 21 % del total de sus especies están amenazadas. El Telmatobius es uno de los géneros más amenazados de esta clase de vertebrado, siendo las principales causas la pérdida y degradación de su hábitat, el tráfico ilegal, el cambio climático y las enfermedades infecciosas. El objetivo de este estudio fue determinar la presencia de hemoparásitos en ejemplares provenientes de decomisos. Se tomaron muestras de sangre de la vena abdominal ventral de 50 ranas del género Telmatobius decomisadas en la ciudad de Lima, y se realizaron frotis sanguíneos que se colorearon con tinción de Wright. Se logró identificar hemogregarinas del género Dactylosoma (familia Dactylosomatidae) en el 14 % (n = 7) de las muestras evaluadas. Este estudio es el primer reporte de la presencia de un hemoparásito en Telmatobius.
¿Son exitosos los empresarios veterinarios? Radiografía de los factores influyentes
Authors: Otero Jorge , Quicaño Isabel
Published: January 2025

La presente investigación cualitativa describe y determina el nivel de éxito de los emprendimientos veterinarios del distrito de El Agustino, Lima, Perú, en el año 2022. Se realizaron dos encuestas, una para los dueños de las veterinarias y otra para los clientes. La primera encuesta consideró solo los negocios que contaban con médicos veterinarios, excluyendo a los que se dedican a la estética y venta de accesorios o alimentos denominados «pet shop». Las variables independientes del estudio son la actitud emprendedora, que involucra cinco factores (necesidad de logro, innovación, control percibido interno, autoestima y toma de riesgos), y la variable factores de producción, que son trabajo y capital. La variable dependiente es el éxito empresarial, que comprende la satisfacción del cliente y las ganancias mensuales del negocio. Metodológicamente, se usaron seis etapas para determinar el nivel de éxito de cada negocio veterinario. La primera etapa evaluó los subindicadores de cada indicador; la segunda, los indicadores de cada factor en categorías de adecuación; la tercera, el factor de cada variable en categorías de éxito; la cuarta, cada variable en categorías de éxito; la quinta, el efecto de cada variable en categorías de éxito; y la sexta, los niveles de éxito de los emprendimientos veterinarios a partir de la relación entre las variables independientes con la variable dependiente. Como resultado, se obtuvo que el 44.44 % de los consultorios veterinarios del estudio son medianamente exitosos según los parámetros utilizados, mientras que el 55.56 % es poco exitoso. En el caso de las clínicas veterinarias, se observó que el 50.00 % es considerado poco exitoso y el otro 50.0 % es mediamente exitoso. No hubo ningún emprendimiento con un nivel completamente exitoso.
Características demográficas, clínicas e imagenológicas de pacientes caninos con alteraciones en las enzimas hepáticas, atendidos en un centro veterinario de Lima, Perú (2019-2023)
Authors: Laguna Mirella , Amarista Manuel , Grandez Ricardo
Published: January 2025

El objetivo del trabajo fue describir las características demográficas, clínicas e imagenológicas de pacientes caninos con alteraciones en las enzimas hepáticas atendidos en un centro veterinario de Lima, Perú, durante el período 2019-2023. El diseño del estudio fue de tipo observacional, descriptivo y de corte transversal. El muestreo fue no probabilístico de tipo censal. Se revisó un total de 116 historias clínicas y se consideraron como variables las características demográficas (sexo, razas, edad), clínicas (signos), bioquímica sanguínea (alanina aminotransferasa [ALT], aspartato aminotransferasa [AST] y fosfatasa alcalina [FA]), y ultrasonográficas. La base de datos se organizó en el software Microsoft Excel (versión 16), se procesó y aplicó la estadística descriptiva con ayuda del software STATA (versión 18). Las características demográficas más frecuentes fueron: sexo macho 56.03 % (n = 65), raza mestiza 52.59 % (n = 61) y edad adulta 44.83 % (n = 52). Los signos clínicos que predominaron en machos, hembras, raza mestiza y pura fueron vómito, diarrea, anorexia, dolor abdominal, decaimiento y fiebre. Los valores bioquímicos se mostraron elevados para las tres enzimas evaluadas y variaron entre AST 53-710 U/L, ALT 68-710 U/L y FA 105-1596 U/L. Por último, las características ultrasonográficas más importantes fueron bordes regulares, aumento de tamaño, parénquima homogéneo y ecogenicidad aumentada. Se concluye que el 10.34 % (n = 12) de los pacientes estaba cursando la fase aguda por presentar calibre del vaso aumentado, ecogenicidad disminuida, tamaño del hígado aumentado y valores elevados de las enzimas (ALT, AST y FA). Asimismo, el 9.48 % (n = 11) cursaba la fase crónica por presentar bordes irregulares, ecogenicidad aumentada, tamaño del hígado normal/conservado y parénquima heterogéneo.
Os níveis de metanefrinas urinárias fracionadas podem estar associados com piores achados histopatológicos no feocromocitoma?
Authors: Aragão Davi Oliveira , Ozório Renan Galvão , Holanda Gabriela Silva , Rebouças Filho Gilberto Nogueira , Alencar Renata Carvalho de , Nogueira Teresa Neuma Albuquerque Gomes , Quidute Ana Rosa Pinto
Published: January 2025

Objetivos: Averiguar se níveis elevados de catecolaminas e perfil predominante de normetanefrina sugerem maior malignidade de tumor feocromocitoma. Metodologia: Selecionou-se oito pacientes, acompanhados no Hospital Universitário Walter Cantídio, sob aprovação do Comitê de Ética (CAAE 51573121.9.0000.5054), portadores de feocromocitoma, possuindo registro dos níveis de metanefrinas urinárias pré-operatórias e do histopatológico da peça cirúrgica de adrenalectomia. Usando escore PASS, formou-se dois grupos de pacientes: G1 (tumor caráter maligno) e G2 (tumor caráter benigno). Comparou-se percentuais excedentes dos níveis de metanefrinas em relação ao valor de referência e percentual de normetanefrina entre G1 e G2. Calculou-se coeficiente de correlação Pearson entre esses parâmetros e escores PASS, para averiguar uma relação direta. Resultados: Dois terços dos integrantes do grupo G1 não possuíam sequer diagnóstico laboratorial de feocromocitoma confirmado, considerando que o aumento de metanefrinas era menor que quatro vezes o limite superior. Quanto ao grupo G2, 80% dos pacientes tinham diagnóstico laboratorial estabelecido. Evidenciou-se normetanefrina urinária predominante para 66% dos pacientes do G1 contra 60% do G2. O coeficiente de Pearson foi aproximadamente zero tanto entre excesso de metanefrinas e PASS quanto entre percentual de normetanefrina e PASS. Conclusão: Não existe relação entre níveis de catecolaminas urinárias ou predomínio de normetanefrina urinária com feocromocitoma maligno.
Распространение вариантов вируса SARS-COV-2, вызывающих интерес (VOI) и находящихся под наблюдением (VUM), на основе количества их геномов, депонированных в базу данных GISAID за неделю с 4 по 10 января 2025 г.
Authors: Дмитриева Людмила , Чумачкова Елена , Краснов Ярослав , Осина Наталья , Зимирова Анастасия , Иванова Александра , Карнаухов Игорь , Караваева Татьяна , Щербакова Светлана , Кутырев Владимир
Published: January 2025

В обзоре представлена информация по циркулирующим в настоящее время вариантам вируса SARS-COV-2 Omicron вызывающих интерес (VOI) и находящихся под наблюдением (VUM), геномные последовательности которых размещены в международной базе данных GISAID за неделю с 4 по 10 января 2025 г.
Catálogo de limpiezas de sangre de la Cofradía de Santa María de la Candelaria de Córdoba (1578-1753) (II)
Authors: Cerro García Alejandro Marco , Girón Pascual Rafael M.
Published: January 2025

Esta publicación recoge la segunda parte del catálogo de las 324 limpiezas de sangre que se conservan de la cofradía cordobesa de Santa María de la Candelaria entre los años de 1578 y 1753. Se presentan las 98 genealogías contenidas en las probanzas de los cofrades y sus esposas cuyos apellidos comienzan por las letras G-P, aportando información de vecindad, filiación, ocupación, o pertenencia a otras cofradías cordobesas y al Santo Oficio de la Inquisición.
Los Planes, 1550-1700. Estudio histórico social de un linaje de mercaderes y ciudadanos de Valencia
Authors: De Ascoz y Planes Óscar
Published: January 2025

En este artículo se analiza, a partir de tres generaciones de la familia Planes, originaria de Mallorca, representadas por Gaspar, su sobrino Bartomeu, ambos mercaderes, y el hijo de Bartomeu, Vicent, ciudadano de Valencia, quien también siguió el camino del comercio, las estrategias de ascenso social que utilizó esta familia para consolidarse como parte de la élite y obtener el estatus de ciudadanos en la sociedad valenciana de época moderna. Este trabajo pretende contribuir al entendimiento de la movilidad social que caracterizó a las sociedades occidentales desde esa época y profundizar más en las estrategias de promoción social de los Planes para definir los comportamientos clave de estas élites a la hora de ascender posiciones gracias a la diversificación de las fuentes de riqueza, a su preeminencia social y a otros elementos culturales diferenciadores.
Identificación de géneros de nemátodos en quina (Cinchona spp.) en bosques de neblina, distrito Kañaris, Lambayeque-Perú
Authors:   , Escobar Coronado Andreina Katarin
Published: January 2025

El presente trabajo de investigación tuvo como objetivo principal la identificación de los géneros de nematodos asociados al árbol de quina (Cinchona spp.) en bosques de niebla del distrito de Kañaris en la región Lambayeque, zona con más investigaciones realizadas por el INIA (Instituto Nacional de Innovación Agraria) donde destaca la quinua roja (Cinchona pubescens). La zona de estudio es de geografía accidentada pero accesible para la toma de muestras. El desarrollo de este proyecto estuvo motivado por, la limitada información sobre esta especie y su entorno, que servirá como fuente de información para futuras plantaciones. La colecta de muestras de suelo del bosque se realizó en tres parcelas, se seleccionó en cada una de ellas 10 árboles al azar. Para la colecta muestras de suelo y raíces a dos profundidades, 14 cm y 28 cm, el área de proyección de la copa del árbol se tuvo como referencia; 1 kg de muestra compuesta por parcela fue extraída. Raíces activas del árbol del mismo punto de extracción de muestras de suelo anterior en la misma proporción fueron colectadas, las cuales fueron trasladadas al laboratorio del SENASA en Lima y procesadas para identificar los géneros de nematodos presentes. Los siguientes órdenes/géneros de nematodos fueron identificados: Rhabditis, Dorylaimus, Tylenchus, Mononchus Trichodorus y Helicotylenchus, considerando la clasificación trófica, de crucial importancia para poder anticipar su estilo de vida y el impacto que tendría en el hábitat de este árbol. En conclusión, es de vital importancia enriquecer la información sobre las especies nativas de valor nacional que se encuentran en vías de recuperación y son de importancia comercial, a fin de contar con una base de datos con información relevante sobre los posibles microorganismos que pueden beneficiar o perjudicar su entorno de desarrollo.
Nivel de conocimiento sobre cáncer oral en odontólogos de la Dirección de Redes Integradas de Salud Lima Sur
Authors:   , Huamani Valverde Josceline Estefania
Published: January 2025

Objetivo: Determinar el nivel de conocimiento sobre cáncer oral en odontólogos de la Dirección de Redes Integradas de Salud Lima Sur. Materiales y Métodos: Participaron 160 odontólogos (58,8% mujeres); edad media 44,3±10,9 años que trabajaban en establecimientos públicos (n=80) y 36,4±9,2 años de edad media en privados (n=80). Un cuestionario se aplicó de manera presencial 2022 - 2023 conteniendo 25 preguntas sobre cáncer oral con cinco dimensiones (epidemiología, etiopatogenia, diagnóstico, tratamiento y prevención) obteniendo validación por 5 expertos (V de Aiken = 0,982) y confiabilidad interna (KR-20 = 0,771). Otros datos recolectados fueron el sexo, los años de experiencia laboral y el grado académico. Las pruebas de Chi cuadrado, Prueba exacta de Fisher y T de Student se utilizaron a un 95% de nivel de confianza. Resultados: El conocimiento de cáncer oral se caracterizó por: puntaje (>15 respuestas correctamente contestadas) y nivel eficiente (36,3%) y regular (35,6%). El nivel regular predominó en las cinco dimensiones (52,5% en etiopatogenia a 69,4% en prevención). Los niveles deficientes fueron más altos en las dimensiones en las dimensiones diagnóstico (43,1%), epidemiología (37,5%) y tratamiento (33,8%). No hubo asociación de los conocimientos por tipo de establecimiento, ni sexo (p≥0,190). Una mayor experiencia laboral se asoció a mayor nivel de conocimiento en la dimensión tratamiento (p=0,005). Un conocimiento preventivo deficiente se asoció a odontólogos sin especialidad del sector público (p=0,014). Conclusiones: Los conocimientos de cáncer oral total y por dimensiones fueron aceptables, teniendo mejores resultados en odontólogos con estudios de posgrado del sector público y con más años de experiencia laboral.
Análisis de la producción científica sobre tuberculosis y atención primaria en salud en Latinoamérica y el Caribe, en la base de datos Scopus: Un estudio bibliométrico
Authors:   , Rabanal Silva Ronald Alejandro , Montalvan Pastor Miguel Alejandro
Published: January 2025

Los sistemas de salud que implementan un modelo de salud basados en atención primaria constituyen un factor esencial para el control de la tuberculosis, cuyo manejo continúa siendo un desafío para varios países de América Latina y una de las razones principales de los fallecimientos por enfermedades infecciosas en América Latina y el Caribe (ALC). El proposito de esta investigación es describir y evaluar las tendencias en la producción científica sobre Tuberculosis y Atención primaria en salud en América Latina y el Caribe. Se realizó un análisis bibliométrico utilizando la base de datos SCOPUS. Se utilizó el software VOSviewer para analizar la red colaborativa, análisis de co-citación y análisis de co-ocurrencia de palabras clave; la herramienta SciVal se empleó para analizar cuantitativamente la distribución de países, instituciones, recuentos de citas, H- index y colaboraciones. Se recopilaron 365,215 artículos, analizamos 13,686 que correspondían a investigaciones de Tuberculosis en America Latina y el Caribe y solo un 5.6% estaban relacionadas a Atención primaria en salud . Se evidenció un incremento en la producción de artículos desde 1978, entre 1998 y 2023, el 96.2% de los artículos fueron publicados. La tendencia revela menos de 8 artículos por año (1978-2000), seguido de un crecimiento constante desde 2000 hasta 2023, con un pico de 21 publicaciones en 2001; identificándose una progresión lineal positiva. La mayor parte de la producción científica correspondió a artículos originales (82.7%), siendo Brasil el país de la región con mayor producción científica (56.2%), seguido de Estados Unidos con (25.4 %) como país extra-regional. La colaboración regional fue baja en comparación con países de altos ingresos. El área más común de investigación por co-ocurrencias fue “Diagnóstico y tratamiento con 47.6 %.
Accounting for Embodied Emissions of Chemicals within the European Carbon Border Adjustment Measure
Authors: Bardow André , Minten Hannah , Hausweiler Julian , Probst Benedict , Reinert Christiane , Meys Raoul
Published: January 2025

The Carbon Border Adjustment Mechanism (CBAM) implemented by the European Union (EU) aims to avoid carbon leakage and drive the transition towards net-zero emissions. As the EU considers extending CBAM to the chemical sector by 2030, its effectiveness in this complex industry remains uncertain. Here, we assess the EU CBAM’s effectiveness using a Life-Cycle Assessment of 4,470 global chemical production facilities. We find that the current CBAM framework accounts for 50–60% of production emissions for key products like ethylene and polyethylene. This limited emission coverage risks compromising the policy’s ambition. To address this, CBAM would need to (1) include fossil feedstocks and refinery products, and (2) implement high fallback default values for embodied emissions to incentivize data reporting. Thus, our study underscores the importance of careful supply chain tracking. Furthermore, we recommend engaging chemical industry experts before policy implementation to ensure CBAM fosters an equitable net-zero transition without unintended consequences.
Neutron Imaging Investigation of AM Tungsten Nozzles for an Arcjet Deorbit System
Authors: Skalden Jonathan , Ehresmann Manfred , Becatti Giulia , Schulz Michael , Gustschin Alex , Kis Zoltán , Szentmiklósi László , Herdich Georg
Published: January 2025

The Institute of Space Systems is currently developing a deorbit module based on thermal arcjet technology to allow fast orbit decay at end-of-life with a focus on mega constellation satellites. By employing additive manufacturing with tungsten, improved nozzle geometries can lead to a gain in overall performance. However, reproducibility is an ongoing concern for additive manufactured parts. Together with the Heinz Maier-Leibnitz Zentrum (MLZ) and the Budapest Neutron Centre of the Centre for Energy Research, a study was conducted scanning additively manufactured arcjet nozzles prior and after standardized operation via neutron computer tomography. The results show a drop in performance over time, which can be related to an increased constrictor diameter and residual powder in the cooling channels.
Downscaling the 100 kW SX-3 AF-MPD to the 5 kW SUPREME Thruster
Authors: Winter Michael , Betancourt Manuel La Rosa , Bögel Elias , Bäcker Michael , Perepechkin Anatoliy , Keil Gregor , Umpiérrez Daniel , Herdrich Georg , Becatti Giulia , Behnke Alexander , Sperber Alessa , Wanke David
Published: January 2025

The SUPREME (Superconductor-Based Readiness Enhanced Magnetoplasmadynamic Electric Propulsion) thruster, in development by Neutron Star Systems DE GmbH (NSS) in collaboration with the Institute of Space Systems (IRS), University of Stuttgart, is designed for a nominal power level of 5 kW to have a wide range of commercial applications. Basis for the design is the SX3 thruster developed at IRS which is an engineering model operated between 2 and 100 kW with magnetic fields up to 400 mT. Both magnetic coil for the applied field and thruster anode are made of copper and are water-cooled. SUPREME will have a radiation cooled anode and a high temperature superconducting coil aiming at nominal maximal magnetic fields of 1.2 T. In the absence of a numerical simulation code for the plasma inside the thruster, the downscaling process described here relies on maintaining critical plasma parameters of the SX3 thruster to produce similar thruster performance with the smaller SUPREME. The downscaling to obtain a discharge unit geometry and the design process for the superconducting coil are described in detail, the SUPREME performance is estimated with a scaling code developed at IRS, and potential mission scenarios are investigated.
Does the Coronal and Sagittal Posture Affect the Risk of Falling in Older Adults with Pain?
Authors: Çelik Gülşah , Toraman Naciye Füsun , Akdağ Ali , Hindistan İbrahim Ethem
Published: January 2025

Purpose: Fall risk in older adults is linked to poor posture and pain, often focusing on sagittal alignment. This study examines the combined impact of coronal and sagittal posture on fall risk in individuals with pain.
Materials and Methods: This prospective cross-sectional study included 146 adults aged 65+ with pain, selected from 479 screened. Participants were categorized as fallers or non-fallers. Data collected included posture (sagittal, coronal, total), pain details, demographics, comorbidities, medication use, timed up-and-go test, Berg balance scale, four-step square test, and number of falls. Analyses used Mann-Whitney U, chi-square, univariate, and multivariate regression models.
Results: Of the 146 participants, 58% had a history of falls, and 71% were females. Neck pain was reported by 28% of participants, knee pain by 39%, and low back pain by 33%. Multivariate logistic regression analysis showed that Berg balance score and total posture score were independently associated with falls (odds ratio 0.8, and 0.9, respectively). This indicated that for every one-unit increase in the Berg score and total posture score, the odds of a fall decreased by about 20% and 10%, respectively.
Conclusion: The study results indicated that assessing the total posture, not just the sagittal posture is crucial when evaluating the risk of falls in older adults. Furthermore, the Berg test proved particularly valuable in assessing the risk of falls among older adults experiencing neck, low back, and knee pain.
Regional Analysis of Hospital Admission Authorizations for the Treatment of Facial Fractures in the State of Paraíba
Authors: Santana Ilan Hudson Gomes , Viana Mayara Rebeca Martins , Ferreira Anderson Jara , Guimarães Camila Coêlho , Zevallos Erick Andres Alpaca , Schwerz Paola Cassia Spessato , Félix Karolayne Dutra , Henriques Maria Eduarda Batista , Cardoso Felipe Germoglio , Ribeiro Eduardo Dias
Published: January 2025

Introduction: External fractures, often the result of traffic accidents and interpersonal violence, represent a public health problem that requires specialized treatment and hospital infrastructure. In Paraíba, the demand for Hospital Admission Authorizations (AIHs) for these injuries has increased over the years, concentrated in large hospitals. This study aims to analyze this demand between 2014 and 2024, providing subsidies for the planning and distribution of health resources.
Materials and Methods: Using AIH data from the DATASUS system, we analyzed types of industrial fractures in state hospitals, including the number of approvals, the average length of hospital stay, and the associated deaths. The methodology involved a descriptive analysis of the evolution of AIHs and the distribution between different hospital doors.
Results and Discussion: The data show a significant increase in AIHs over the period, with a greater concentration in referral hospitals, such as the Dom Luiz Gonzaga Fernandes Hospital and the Senador Humberto Lucena Hospital, which handle most of the complex cases. The mortality rate was low, but the rate of hospitalization varied between hospitals, reflecting the complexity of the cases. The results indicate the need to decentralize care and strengthen regional hospitals in order to improve access and reduce the overload on large centers.
Conclusions: The study highlights a growing demand for treatment of bone fractures and the importance of strategic planning to strengthen regional hospitals and implement prevention policies, ensuring more equitable and efficient care for the population affected by facial trauma.
Comparison between single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) and roux-en-y gastric bypass (RYGB) in terms of weight loss, comorbidities remission and complications. A Systematic Review with Meta-analysis.
Authors: Sabatella Lucas , Jover Daniel Aliseda , Ortega Patricia M , Asensio Nuria Blanco , Ojanguren Carlota Tuero , Pagola Adriana Uriz , Acha Manuel Fortún Landecho , Azcárate Victor Valentí
Published: January 2025

Purpose
Evaluate and compare the results of weight loss outcomes, comorbidities resolution and complications in the short and long-term between SADI-S and RYGB.
Material and methods
A systematic review was conducted following PRISMA guidelines. Studies comparing SADI-S and RYGB as primary surgery were included if they reported weight loss (total weight loss (TWL), excess weight loss (EWL), or body mass index (BMI) changes), comorbidity remission (diabetes and hypertension), and postoperative outcomes (complications, hospital stay, and operative time). A meta-analysis of mean differences (MD) was conducted to assess continuous outcomes and a meta-analysis of odds ratios (OR) was performed to evaluate the categorical variables, random effects model was used.
Results
Nine studies, including 51,634 patients (2,126 SADI-S; 49508 RYGB), were analysed. Six studies with over one year of follow-up [Mean 3.93 years (1.79)] were included for long-term outcomes, while all nine were considered for short-term outcomes. SADI-S resulted in a statistically significant higher total weight loss (MD 10.02; 95% CI 4.21–15.82; p < 0.001), excess weight loss (MD 10.3; 95% CI 6.9–13.7; p < 0.001) and diabetes remission (OR 3.48; 95% CI 2.02–6.02; p < 0.001). Short-term complications (OR 0.95; 95% CI 0.45–1.97; p = 0.89) and severe complications (OR 0.65; 95% CI 0.22–1.91; p = 0.43) were similar between groups, but SADI-S had fewer long-term complications (OR 0.17; 95% CI 0.04–0.66; p = 0.01). Operative time (MD 9.2; 95% CI -26.3–44.8; p = 0.6), and hospital stay (MD 0.06; 95% CI -0.69–0.82; p = 0.86) were comparable.
Conclusion
This meta-analysis suggests that SADI-S may offer advantages over RYGB in terms of weight loss and diabetes remission, with a similar safety profile regarding short-term complications and potentially fewer long-term complications.
Suppression of skin lesions and SLE nephritis by increasing Treg in MRL/FASlpr mice by administration of Bee venom Apitoxin®
Authors: Cho Duk-Yeon , Kang Young-Mo , Seol Sang-Ho
Published: January 2025

Background: Apitoxin®, a drug based on bee venom was approved and released in Korea in 2003 as the Ethical drug (ETC). It is well-known for its pain-relieving properties due to its potent anti-inflammatory effects. This raises the question of whether bee venom has benefits for other inflammatory disorders. Since its effectiveness in treating inflammation and pain associated with autoimmune diseases has been observed in several clinical cases in Korea, we conducted an efficacy using an animal model of the systemic lupus erythematosus (SLE), an autoimmune disease of with high medical unmet needs. In this research, we aim to confirm the potential therapeutic efficacy for SLE through the immunomodulation induced by bee venom.
Methods: MRL/FASlpr mice were injected subcutaneously with Apitoxin® and evaluated for clinical parameters including proteinuria, skin lesions, and lymphadenopathy, flow cytometric evaluation of regulatory T cells (Treg), quantitative evaluation of anti-dsDNA antibody in serum by ELISA, and histomorphometric analysis of kidney tissues.
Results: Treatment with Apitoxin® revealed a reduction in proteinuria, skin lesions, and lymphadenopathy in MRL/FASlpr mice. The percentage of CD3+CD4+CD25+FoxP3 (Treg) cells, which are associated with autoimmune diseases, was increased compared to the negative control (vehicle). Quantitative analysis of autoantibodies in the blood of MRL/FASlpr mice showed a decreasing tendency in the treatment groups with Apitoxin®. Moreover, mesangial proliferation and inflammatory cell infiltration in glomeruli were significantly reduced in treatment group with Apitoxin®, which was associated with a statistically significant decrease in the amount of IgG infiltrated into the glomeruli.
Conclusion: Overall, the results confirmed that Apitoxin® induced clinical improvement in SLE by increasing the proportion of Treg cells and decreasing anti-dsDNA antibodies in the blood, which results in therapeutic effects on glomerulonephritis associated with decreased renal infiltration of immune complexes.
Longitudinal Quantitative Assessment of Retinal Crystalline Deposits in Bietti Crystalline Dystrophy
Authors: You Seung Jun , Yoon Chang Ki , Park Un Chul , Park Kyu Hyung , Lee Eun Kyoung
Published: January 2025

Background
This study aims to quantitatively analyze retinal crystalline deposits in patients with Bietti Crystalline Dystrophy (BCD) and examine their progression over time in a longitudinal study.
Methods
We retrospectively reviewed consecutive patients diagnosed with BCD at a single center. Retinal crystalline deposits were quantified from fundus photographs using semi-automated software, which divided the macular area into a central foveal circle, inner ring, and outer ring. We then analyze changes in the amount and intensity of these deposits over a two-year period.
Results
The study included 30 eyes from 16 patients. Mean crystal intensity was 1.158 ± 1.425% in the central foveal circle, 1.043 ± 1.444% in the inner ring, and 0.990 ± 0.969% in the outer ring, with no significant differences observed between the regions (all P > 0.05). Over the two-year study period, there was a gradual decrease in both the amount and intensity of the crystals in all zones. However, these changes were not statistically significant (all P > 0.05).
Conclusions
The use of semi-automated software to analyze fundus photographs provided a quantitative method for assessing retinal crystalline deposits in BCD. This longitudinal study enhanced our understanding of the disease’s natural progression.
Hospital-Based Analysis of Early-Onset Diabetes in Ghana's Upper East Region: Prevalence, Complications, and Challenges
Authors: Solomon Beletaa , Kaba Ceasar , Mensah Joy Afua , Helegbe Gideon Kofi , Abugri James , Adadey Samuel Mawuli
Published: January 2025

Diabetes mellitus is the most prevalent endocrine disorder in individuals under 30 years, encompassing type 1 diabetes mellitus (T1DM), early-onset type 2 diabetes mellitus (T2DM), monogenic diabetes, and maturity-onset diabetes of the young (MODY). This study investigated the prevalence, diagnosis, types, and complications associated with early-onset diabetes in Ghana, utilizing hospital data from 52 patients under 30 years of age. Among them, 20 patients were under 20 years. T1DM was diagnosed in 15 patients, while only one case of T2DM was identified. Secondary diabetes with unknown etiologies was the most common diagnosis (22 cases), indicating the potential presence of undiagnosed monogenic diabetes or MODY. Reported complications included diabetic foot (5 cases), diabetic nephropathy (2 case), infections (4 cases), retinopathy (4 cases) and ketoacidosis (13 cases). While most patients recovered and were discharged, 3 deaths, 1 referral, and 1 absconded case were recorded. These findings highlight the importance of accurate diagnosis, targeted management strategies, and further research into secondary diabetes and its potential underlying causes in Ghana. The study underscores the need for improved diagnostic capabilities, awareness, and healthcare resources to address early-onset diabetes and its complications in the country.
The Role of Mid Regional Pro-adrenomedullin as a Biomarker for Early Cardio-Renal Dysfunction in Prediabetes and Type 2 Diabetes Mellitus _ A Prospective cohort study
Authors: Rao Oshmi , Kumar J.S.
Published: January 2025

Background:Cardiovascular and renal complications are leading causes of morbidity and mortality in patients with Prediabetes type 2 diabetes mellitus (T2DM). Identifying reliable biomarkers for early detection of cardio-renal dysfunction is essential to mitigate disease progression and improve clinical outcomes. This prospective cohort study evaluates the association between serum Mid-Regional Pro-adrenomedullin (MR-ProADM) levels and early signs of endothelial dysfunction in patients with prediabetes and T2DM.
Method: The study was conducted at SRM Medical College Hospital and Research Centre, involving 90 participants divided equally into prediabetic and T2DM groups. Comprehensive clinical assessments included measurements of MR-ProADM, NT-ProBNP, eGFR, urine albumin-to-creatinine ratio (ACR), lipid profiles, and glycated hemoglobin (HbA1c). All these petameters are measured at baseline as well as after 1 year of follow-up.
Finding: The study observed a significant increase in serum MR-ProADM levels in prediabetic and T2DM patients during follow-up compared to baseline. MR-ProADM correlated positively with early markers of endothelial dysfunction and cardio-renal impairment. Linear regression analysis confirmed strong associations with NT-ProBNP, Ejection fraction, eGFR, and ACR, indicating its potential as a predictive biomarker for cardiovascular and renal complications. ROC curve analysis further validated MR-ProADM’s diagnostic utility in identifying patients at risk. This study highlights MR-ProADM’s clinical relevance as a stable, reliable marker for early detection, risk assessment, and timely intervention in prediabetic and T2DM populations.
Interpretation: Serum MR-ProADM shows potential as a reliable biomarker for early detection of cardio-renal dysfunction in prediabetes and T2DM. Its significant correlation with NT-ProBNP, Ejection fraction, eGFR, and ACR highlights its utility in predicting cardiovascular and renal complications, enabling timely intervention to improve clinical outcomes.