bluuebunny/crossref_metadata_2025 huggingface dataset:
QUALITY OF LIFE ASSESSMENT IN THE HEART FAILURE PATIENTS TAKING STANDARD MEDICAL CARE IN TEACHING HOSPITAL
Authors: PRIYANKA SHARMa  , MD SAYEED AKHTAR  , FAUZIA TABASSUM  , NIMISHA TANDON  , ANSHU NANDA
Published: December 2019

Objective: This study was aimed to assess the quality of life (QoL) of the subjects having congestive heart failure (HF) under different domains of life, such as physical, psychological, and social domains, and they started taking the standard care treatment.

Methods: The questionnaire-based prospective study was designed to assess the effects of the HF in different domains of life such as social, psychological, physical, or mental. After getting consent from the subjects, health questionnaire was provided to a total of 60 subjects.

Results: We found drastic improvements in 24% of total HF cases in terms of physical debility, whereas only 15% patients reported none of the complications during taking standard care therapy. Total 32.5% patients aware of the treatment took and to whom contact in an emergency. Psychological disturbances and life satisfaction were observed in 16.66% and 33.33% cases suffering from HF. Patient compliance means personal life, as well as medication adherence, was observed in only 53.33%.

Conclusions: The results obtained from the responses given by the patients in the health questionnaires demonstrated that the HF patients’ needs awareness regarding the therapy precautions that improving the QoL of patients.
DESIGN AND FORMULATION DEVELOPMENT OF FAST-DISSOLVING TABLETS OF IBUPROFEN USING NOVEL NATURAL SUPERDISINTEGRANT
Authors: CHANDRA SEKHAR NAIK D  , BHARATHI A  , BASAVESWARA RAO MV
Published: December 2019

Objective: The objective of the study was to evaluate Ocimum gratissimum mucilage as a novel superdisintegrant in the formulation of fast-dissolving tablets (FDT) of Biopharmaceutical Classification System-II drug (Ibuprofen) employing a 23 factorial design.

Methods: O. gratissimum mucilage was extracted by seeds and it was subjected to physical, chemical, and micrometric studies were evaluated. To establish FDT of ibuprofen with O. gratissimum mucilage as a superdisintegrants in different ratios using direct compression method employing 23 factorial design. All the formulation tablets were evaluated pre-compression and post-compression parameters like dissolution efficiency (DE%) percent of drug dissolved at 5 min.

Results: The mucilage was to be found fine, free-flowing crystalline powder, and excellent swelling nature in all suitable solvents and buffers. The Fourier transform infrared and differential scanning calorimetry studies were indicated to no interactions between ibuprofen and O. gratissimum mucilage. All the FDT formulated employing novel mucilage shows good quality with regard drug content (98.05±0.31–99.39±0.54), hardness (3.6– 4 kg/sq. cm), and friability (0.12–0.15%). The optimized formulation batch shows less disintegrant time (30±0.06). In vitro wetting time was less (i.e., 90 s) in optimized formulation F2. The water absorption ratio of the formulated tablets was found to be in the range of 99±0.56. The cumulative drug dissolved in the optimized formulation F2 was found to be 99% in 10 min.

Conclusion: O. gratissimum mucilage was found to be a novel superdisintegrant which enhanced the DE when combined with crospovidone and croscarmellose sodium; hence, it could be used in the formulation of FDT to provide immediate release of the contained drug within 5 min.
THE IMPACT OF DIFFERENT REGIMENS OF VITAMIN D3 ON GLUCOSE HOMEOSTASIS IN TYPE 2 DIABETIC PATIENTS
Authors: SAMIA MOHAMED ALI  , YEHIA MOSTAFA GHANEM  , OLA ATEF SHARAKI  , WAFAA AHMED HEWEDY  , ESRAA SAEED HABIBA
Published: December 2019

Objective: Vitamin D has a role in the regulation of pancreatic β-cell function and insulin sensitivity. Accordingly, Vitamin D deficiency is considered to be a risk factor for the development of type 2 diabetes mellitus (T2DM) and its complications. Therefore, the aim of the study was to assess and compare the effect of different regimens of Vitamin D3 on glucose homeostasis in patients with T2DM.

Methods: The study included 80 patients with T2DM taking oral antidiabetic drugs. The patients were randomized to receive antidiabetic drugs alone or with different regimens of Vitamin D3 for 3 months. Vitamin D3-treated patients were supplemented by either daily oral 4000 IU Vitamin D3, weekly oral 50,000 IU Vitamin D3, or a single parenteral dose of 300,000 IU Vitamin D3. In addition to the assessment of patient characteristics, laboratory measurements of serum creatinine, blood urea, total and ionized calcium, serum phosphorus, fasting blood glucose, fasting serum insulin, homeostasis model assessment of insulin resistance, hemoglobin A1c, and 25(OH) Vitamin D levels were measured at the beginning and after 3 months.

Results: After 3 months, the increased Vitamin D levels resulting from the daily and weekly oral doses of Vitamin D3 caused a significant decrease in metabolic parameters, whereas the parenteral dose demonstrated a non-significant decrease.

Conclusion: Oral daily and weekly doses of Vitamin D3 could improve glucose homeostasis equally in patients with T2DM and better than a single parenteral dose of Vitamin D3.
ISOLATION OF UROPATHOGENS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN AT A TERTIARY CARE HOSPITAL IN NORTHERN INDIA
Authors: HARIT KUMAR  , VARSHA A SINGH  , SHAVI NAGPAL  , DIPANKAR BISWAS
Published: December 2019

Objective: The objective of the study was to know the isolation rate and antibiotic susceptibility pattern of pathogens causing urinary tract infection (UTI).

Methods: A total of 500 urine samples of clinically suspected UTI were collected from January 2019 to June 2019. The samples were inoculated on Cystine Lactose Electrolyte-Deficient agar and incubated at 37°C for 24 h.

Results: In our study, 303 (60.6%) samples showed growth of isolates. Among 303 isolates, 31 were Candida spp. which was not included in the study. Out of 272 isolates, Escherichia coli was 31.68%, followed by Klebsiella spp. (27.72%), Enterococcus faecalis (22.44%), Citrobacter spp. (3.96%), Staphylococcus aureus (2.64%), and Pseudomonas spp. (1.32%). For Gram-negative and Gram-positive isolates, the most effective antibiotic was nitrofurantoin.

Conclusion: The study shows E. coli as the predominant pathogen that causes UTI. Nitrofurantoin and fosfomycin showed very high susceptibility to uropathogens and can be used to treat primary or uncomplicated UTI.
Effects EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) SEED POWDER ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN-INDUCED MICE
Authors: NOVARIANTI MARBUN  , RUTH MAYANA RUMANTI
Published: December 2019

Objective: The aim of this research is to evaluate the antidiabetic effect of pumpkin seed powder in streptozotocin (STZ)-induced diabetic mice.

Methods: Pumpkin seed was used in seed powder suspension form and then evaluate the phytochemical screening and induced diabetic mice using STZ.

Results: The phytochemical screening showed that pumpkin seed powder has various of phytochemical compounds. The pumpkin seed powder (dose level 100, 150, and 200 mg/kg bw) showed a significant reduction of blood glucose.

Conclusions: Pumpkin seed powder significantly decreases blood glucose level in STZ-induced mice.
ASSESSMENT OF THE CURRENT GERIATRIC PHARMACEUTICAL CARE IN THE UNITED ARAB EMIRATES
Authors: OSAMA MOHAMED IBRAHIM  , RANA IBRAHIM
Published: December 2019

Objectives: The primary goal of this study is to assess the current geriatric pharmaceutical care and patient satisfaction among elderly patient. Another aim is to increase the awareness among pharmacists in providing better guidelines for proper geriatric pharmaceutical care in the United Arab Emirates (UAE).

Methods: A pilot observational study was done through the dissemination of cross-sectional surveys among pharmacists and geriatrics in the Emirates of Abu Dhabi, Dubai, and Sharjah. Three hundred and eight pharmacists and 110 geriatric patients were randomly selected to participate in the study.

Results: Among pharmacists participating in the study, 32.1% were from Abu Dhabi, 37.6% from Dubai, and 30.1% from Sharjah. Geriatric patients who participated from Abu Dhabi were 30.0%, 38.1% were from Dubai, and 31.8% were from Sharjah. Geriatrics level of satisfaction was higher in Abu Dhabi compared to Sharjah and Dubai (p=0.0005). Pharmacists in Sharjah and Dubai had higher interest in taking special courses on how to deal with elderly patients compared to pharmacists in Abu Dhabi (p<0.0001).

Conclusions: Geriatrics satisfaction toward pharmaceutical care is not the same in all Emirates of the UAE. This calls for implementing diverse measures such as providing training courses for pharmacists specialized in geriatrics care, which aims to provide a high-quality pharmaceutical care to all geriatrics in the UAE.
EVALUATION OF ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICALS ANALYSIS OF WHOLE PLANT EXTRACT OF VINCA ROSEA
Authors: ANGELIN JEBAMALAR JAYARAJ  , JOTHI UCHIMAHALI  , THIYAGARAJAN GNANASUNDARAM  , SIVAKUMAR THIRUMAL
Published: December 2019

Objectives: The aim of this research work was to find out the antibacterial activity and phytochemical analysis of whole plant extracts (shoot, flower, and root) of Vinca rosea.

Methods: In recent work, phytochemicals were extracted from various parts of the plants using various solvents ethyl acetate (ETOAC), ethanol (ETOH), and dimethyl sulfoxide (DMSO). These phytochemicals contain alkaloids, terpenoids, tannins, flavonoids, aminoacids, saponins, aromatic acids, phenolic compounds, triterpenoids, xantho proteins, PHILOBATININS, carbohydrate, reducing sugar, and proteins; and they were separated by the standard methods. Moreover, antimicrobial activities of methanolic separation were determined by a different species of bacteria and fungi. Agar well-diffusion method was used for the antimicrobial activity, and also analyzed the zone of inhibition.

Results: The evaluation of phytochemical screening of extracts indicated the existence of alkaloids, terpenoids, tannins, flavonoids, aminoacids, saponins, aromatic acids, phenolic compounds, triterpenoids, xantho proteins, philobatinins, carbohydrate, reducing sugar, and proteins. All the tested bacteria and fungi were controlled efficiently, and the activities of the shoot extracts were better compared to flower and root extracts. ETOH extract of the shoot exhibited highest antifungal activity against Candida albicans, (17.34 mm), followed by Candida krusei (16.12 mm), Aspergillus niger (15.76), Mucor sp. (14.67 mm), and Rhizopus oryzae (13.46 mm), ETOH extract of the shoot exhibited highest antibacterial activity), when compared to flower and root extracts against Staphylococcus aureus (12.77 mm), followed by Pseudomonas aeruginosa (11.67 mm), Salmonella abony (10.23 mm), Escherichia coli (9.65 mm), Micrococcus luteus (8.95 mm. V. rosea shoot extracts highlighted effective antifungal activities compared with flower and root extracts against all the tested bacteria.

Conclusion: Current studies have shown that the V. rosea plant contains significant antimicrobial activities in the ETOH extracts. The strong antifungal and antibacterial activities of V. rosea are owing to the presence of saponin, tannins, and flavonoids present in.
SOLUBILITY ENHANCEMENT OF GLIBENCLAMIDE USING MESOPOROUS SILICA
Authors: Mittal Swati , AKSHAY SONAWANE  , MANGESH KHUNE
Published: December 2019

Glibenclamide is a BCS Class II drug and poses a major problem during formulation development. In the present study, adsorption onto various carriers was used to enhance the solubility of glibenclamide. It was observed that solubility of glibenclamide was greatly enhanced by adsorbing onto mesoporous silica. The increase in solubility of poorly soluble drugs is often associated with the generation of supersaturation, which results in the risk of drug precipitation. HPMC E5 was used as precipitation inhibitor to maintain sink condition for a longer duration. A 32 full factorial design was adopted to optimize the ratio of glibenclamide (X1) and mesoporous silica as a carrier (X2) and the effect of different ratios was studied on percent yield, percent drug loading, and percent drug release. X-ray powder diffraction (XRPD) and Differential scanning calorimetry studies were performed to investigate any possible interaction in between glibenclamide and mesoporous silica. An optimum batch of drug adsorbate was used to prepare immediate-release tablets. The tablets prepared were evaluated for thickness, uniformity of weight, hardness, friability, in-vitro disintegration time, and in vitro drug release study.
N-ACETYLCYSTEINE, A BOON FOR YELLOW PHOSPHORUS-INDUCED ACUTE LIVER FAILURE? A CASE REPORT
Authors: AASHIQ AHAMED SHUKKOOR  , NIMMY ELIZABETH GEORGE  , SARAVANAN THANGAVELU
Published: December 2019

Rat killer, in the form of a paste, is a commonly used rodenticide in India. It contains 3% yellow phosphorus, which is a local and a systemic toxin that damages all tissues it contacts. The lethal dose of yellow phosphorus is about 1 mg/kg of body weight. We present a case report of a 30-year-old female patient with an alleged history of intake of 30 g rat killer paste mixed with one glass juice with suicidal intent. She presented with clinical features of acute liver failure (ALF) and was treated with N-acetylcysteine (NAC) infusion with other supportive therapy and recovered completely within 13 days. Poisoning with yellow phosphorus needs to be studied in the aspect of treatment, due to the lack of any specific antidote. The patient factors that help in the recovery also need to be investigated. Although highly lethal, the recovery of ALF due to yellow phosphorus-containing rodenticide is possible. Early intravenous administration of NAC, which acts as glutathione substitute, anti-inflammatory agent, and anti-oxidant could contribute to complete resolution of ALF in yellow phosphorus poisoning.
A VALIDATED ANALYTICAL METHOD FOR THE SIMULTANEOUS ESTIMATION OF CYTARABINE AND DAUNORUBICIN IN BULK AND INFUSION FORMULATION BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
Authors: PRASANTHI CHENGALVA  , LATHA LAVANYA PEDDAVENGARI  , MADHAVI KUCHANA
Published: December 2019

Objective: The novel liposomal infusion formulation of cytarabine and daunorubicin liposomal infusion is considered as new hope in acute myeloid leukemia treatment. The objective of the present study is to develop and validate a simple, rapid, accurate, precise and sensitive reverse-phase high-performance liquid chromatographic (RP-HPLC) method for the simultaneous estimation of cytarabine and daunorubicin in bulk and infusion formulation.

Methods: The chromatographic separation of the drugs was achieved on Denali C18 (250 mm×4.6 mm, 5 μm) in isocratic mode with mobile phase consisting of water (pH was adjusted to 3):acetonitrile in the ratio of 55:45 with a flow rate of 1 ml/min at a detection wavelength of 240 nm using photodiode array (PDA) detector. The column temperature was set at 30°C with 10 μl injection volume. The proposed method was validated as per the International council for Harmonisation (ICH) guidelines.

Results: The retention times for cytarabine and daunorubicin were found to be 2.323±0.12 min and 3.140±0.16 min, respectively. Linearity (r2=0.999) was observed over a concentration range of 16.2–97.5 μg/ml for cytarabine and 7.2–43.5 μg/ml for daunorubicin. The percentage relative standard deviation (RSD) for precision studies was found to be 0.2 for both the drugs.

Conclusion: A simple, rapid, economic, accurate, and precise RP-HPLC method was developed for simultaneous quantitative estimation of cytarabine and daunorubicin, and the method was validated as per the ICH guidelines. Hence, the method can be employed for the routine analysis of cytarabine and daunorubicin in bulk and infusion formulation.
ANTIFUNGAL EFFICIENCY OF COPPER OXYCHLORIDE-CONJUGATED SILVER NANOPARTICLES AGAINST COLLETOTRICHUM GLOEOSPORIOIDES WHICH CAUSES ANTHRACNOSE DISEASE
Authors: RAGHAVENDRA SN  , RAGHU HS  , DIVYASHREE K  , RAJESHWARA AN
Published: December 2019

Objectives: Anthracnose disease is caused by Colletotrichum gloeosporioides, affecting most of the fruit and vegetable plants. The present study is aimed to synthesize silver nanoparticles (AgNPs) using neem extract and conjugate then with fungicide to check the antifungal activity against anthracnose disease.

Methods: In the current study, we have synthesized copper oxychloride-conjugated AgNPs (COC-AgNPs) by a biological method using neem extract and have tested their effectiveness against C. gloeosporioides. The COC-AgNPs were characterized by UV–visible spectroscopy, fourier-transform infrared, scanning electron microscopy, and X-ray diffraction analysis, and in vitro antifungal activity was investigated.

Results: The shape of COC-AgNPs was found to be spherical with an average particle size of 21–25 nm. The fungicide-conjugated AgNPs exhibited highest growth inhibition of C. gloeosporioides (~187%) as compared to fungicide copper oxychloride.

Conclusion: These results indicate that the COC-AgNPs could be effectively used to control anthracnose disease in mango and in other crops. These COC-AgNPs can drastically reduce the amount of fungicide currently used which will reduce the environmental pollution caused by the fungicide.
SYNTHESIS AND OPTIMIZATION OF GEMCITABINE-LOADED MIL-101NH2 (Fe) NANOCARRIERS: RESPONSE SURFACE METHODOLOGY APPROACH
Authors: PREETI KUSH  , JITENDER MADAN  , PARVEEN KUMAR
Published: December 2019

Objective: The objective of the present study is to synthesize and optimize gemcitabine (GEM)-loaded MIL-101NH2 (Fe) nanocarriers. The design of experiments is used to optimize the formulation for higher encapsulation efficiency (EE) for effective drug delivery.

Materials and Methods: MIL-101NH2 (Fe) was synthesized by microwave-assisted hydrothermal method. Central composite design (CCD) under response surface methodology was used for the optimization of GEM encapsulation into the MIL-101NH2 (Fe). The most influential variable that affects the EE was investigated by Perturbation plot. Validation of the design was carried out by performing the experiments under optimal conditions. Further optimized formulation was physicochemically characterized for particle size, surface charge, and surface morphology using zetasizer and scanning electron microscopy (SEM), respectively. Structural integrity of the optimized formulation was carried out by Powder X ray crystallography (PXRD). Fourier-transform infrared (FTIR) spectroscopy was used for the confirmation of GEM loading. Accelerated storage stability analysis was also performed to find out the related parameters.

Results: Here in this work, crystalline MIL-101NH2 (Fe) has been successfully synthesized by microwave radiation method. The optimization result revealed that process variables such as GEM concentration, pH, and time significantly affect the desired constraint, EE. Perturbation plot evidenced that among all the variables, pH is the most significant factor followed by drug concentration and time. The optimized formulation exhibited 76.4 ± 7% EE and average particle size of 252.9 ± 9.23 nm. PXRD and SEM results demonstrated that the optimized formulation was crystalline in nature. FTIR spectroscopy confirms the presence of drug inside the MIL-101NH2 (Fe). In vitro release profile revealed that MIL-101NH2 (Fe)-GEM exhibited the sustained release up to 72 h in comparison to the native GEM. Storage-stability studies also indicate that MIL-101NH2 (Fe)-GEM has a shelf life of 6 months.

Conclusion: The EE of GEM in MIL-101NH2 (Fe) can be altered by varying the drug concentration and pH during the impregnation.
Development and validation of Spectrophotometry methods for estimation of linezolid in bulk and in pharmaceutical Dosage formulation
Authors: Mali Rink R. , Gorle A.P.
Published: December 2019

A simple, precise and economical, and rapid Spectrophotometric methods for the quantification of Linezolid in bulk material and in tablets. Further, this study is designed to validate the developed methods as per ICH guidelines. Material & methods: In Methods A and B, a stock standard solution was prepared by dissolving 10 mg of Linezolid in 100 mL of phosphate buffer pH 7.4 to obtain a concentration of 100 μg/mL. After suitable dilution, 10 μg/mL of  Linezolid was prepared and scanned in the UV-visible range 400 –200 nm;  In method A zero order spectrum Linezolid showed a maximum absorbance at 251 nm. while in Method B  area under curve (AUC) zero-order spectrum was recorded between 245 and 268 nm. For a linearity study, series of dilutions were prepared from stock solutions. Results: In Method A and B, Linezolid followed linearity in the concentration range of 3 – 18 μg/mL with (r2 = 0.9978) (r2 = 0.9981). The accuracy of the method was checked by recovery experiment performed at three different levels i.e., 80%, 100% and 120%. The % recovery was found to be in the range 96.15% – 99.32% for method A, while in method B range is 99.16 % - 100.20 %. The low values of % RSD are indicative of the accuracy and reproducibility of the method. The precision of the method was studied as an intra-day, inter-day variations and repeatability. The % R.S.D. value less than 2 indicate that the method was precise. Ruggedness of the proposed method was studied with the help of two analysts. The proposed method of pharmaceutical formulation the amounts of Linezolid estimated by both these methods (A and B) were found to be 96.25 ± 0.44 and 99.48 ± 1.05, respectively. Conclusion: The developed methods are simple, precise, rugged, and economical. Both these methods can be used for routine analysis of Linezolid from its tablet formulation.

Keywords: Linezolid, UV-Spectrophotometric methods, area under curve, zero order spectrum
Area Under Curve UV Spectrophotometric Method for Determination of an Opioid Analgesic in Bulk
Authors: Gandhat Snehal G. , Dhoble Shankar M. , Kakade Vrushali B.
Published: December 2019

see PDF for full contant
Development and Validation of RP-HPLC Method for Desoximetasone in Bulk and Cream Formulation
Authors: Gorle Ashish , Mahajan Jayashri , Bhave Prathamesh
Published: December 2019

Desoximetasone chemically is 9-fluoro-IIβ21-dihydroxy-I6a-methylpregna-I.4-diene-3.The precise mechanism of the anti-inflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. So, in present investigation chromatographic methods were developing use RP-HPLC for estimation of Desoximetasone in bulk and in cream formulation and method validation according to ICH guidelines. The main objective of this study was to develop a simple and reproducible method for desoximetasone by Reverse Phase High Performance Liquid Chromatography (RP-HPLC). In this work the desoximetasone separation was carried out by using C18 cosmosile column (250mmx4.6mm particle size 5µm). By using 0.1% orthrophosphoric acid pH adjusted up to 3 at uv detection of 240nm.The mobile phase was used at various ratio for gradient elution the ratio of mobile phase was 20:80 v/v. Methanol and water used for mobile phase and flow rate was being set at 1mL/min. The linearity of proposed method was found in range of r =0.9989. Statistically validation parameters such as linearity, accuracy, precision, LOD and LOQ were checked.

Keywords: Desoximetasone, RP-HPLC, Method validation.
Analysis of minerals under different water stress levels in Andrographis paniculata (Burm.f.) Wall. Ex Nees
Authors: Bhargavi Bhattu , Kalpana Kaloori , Kistamma S
Published: December 2019

Medicinal plants have diverse use in the society from medicine to cosmetics to herbal foods with vast potential for their curative medicinal properties. Minerals are essential nutrient for plant metabolism and over all growth of the plants.  The overall growth of the plant depends upon the availability of the water. The aim of this study was to determine the mineral content under different water stress levels in Andrographis paniculata. The homogenized leaf samples of controlled plants(Daily watered), treated T2 plants(watering 2nd day), T4 plants(watering on every 4th day), T7 plants(watering on every 7th day) were subjected to overnight HN03 digestion and analyzed for the presence of Copper, Chromium, Iron, Aluminum, Zinc, Manganese and Phosphorous.  With increase in water stress, element content deceased with varied fractions. The T2 treated plants, irrigated every second day, could withstand the water stress conditions without affecting minimum mineral content in Andrographis paniculata plants and T2 treatment has been chosen the best option to withstand water stress conditions.

Keywords: Andrographis paniculata, water stress, minerals.
Mapping the timber industry complex of Siberia and wood potential for its development
Authors: Makarenko E.L.
Published: December 2019

The purpose of the work is to map the modern location, structure and development of the logging, wood-working, pulp-and-paper and chemical industries of the Siberian timber industry (within the borders of Eastern and Western Siberia), as well as the wood and raw material resource necessary for its development, using statistical, comparative analytical and cartographic research methods. The relevance of the study is due to the important role of forest industries in general economic development of the country, especially in connection with the implementation of the Strategy for the development of the forest complex of the Russian Federation until 2030. As a result, a comprehensive map of the inventory type “Timber industry complex of Siberia” and a synthetic map of the assessment type “Exploitative potential of wood resources of Siberia” were developed. The thematic content of the first map presents forestry centers and their sectoral structure; centers for the integrated processing of wood raw materials; wooded areas, major logging areas. On the second map, wood-raw material resources are estimated from the point of view of their potential exploitation within 17 forest resource areas.
The Potensi Penyakit Tular Vektor Di Kabupaten Pangkajene Dan Kepulauan Propinsi Sulawesi Selatan
Authors: Setiyaningsih Riyani , Setiyaningsih Riyani
Published: December 2019

Pangkajene and Kepulauan Islands is one of the potential districts of vector-borne diseases because it is found variation species of mosquito previously known as disease vectors. The purpose of this research is to know the potential of transmission of malaria, dengue fever, chikungunya, filarisis and japanese encephalitis in Pangkajene and Kepulauan. Catching of mosquitoes is done in forest, non forest and coastal ecosystems. Methods colection of mosquito and larva refer to WHO Standart . The methods used were human landing collection, animal baited trap net, livestock feed, morning resting. The larva survey was conducted at the mosquito breeding place. Mosquitoes in pathogen detection in the laboratory using PCR. Based on the results of pathogen species inspection of a positive plasmodium are Anopheles vagus in a residential ecosystem near settlement, Anopheles subpictus in forest ecosystems near settlement and non forest remote settlement, Anopheles barbirostris in near and remote forest ecosystems, Anopheles indifinitus in nearby forest ecosystems and non-forest close settlement. Culex tritaeniorhynchus positive japanese encephalitis virus in non-forested residential ecosystem. No positive samples were found for dengue fever virus, chikungunya and filariasis, but found mosquitoes based on previous studies into dengue fever vector, chikungunya, and filariasis. Pangkajene and Kepulauan Islands have the potential to spread infectious disease of malaria, dengue hemorrhagic fever, chikungunya, filariasis and japanese encephalitis.
ADAPTATION OF LEAN PRODUCTION TOOLS TO EDUCATIONAL ACTIVITIES OF UNIVERSITIES
Authors: Kucheryavenko Svetlana A. , Chistnikova Irina V. , Thorikov Boris A. , Nazarova Anastasia N.
Published: December 2019

The use of lean technologies can improve the quality of services and the efficiency of available resource spending, stimulate the development of the country economy and improve the living standards of the population. Authorities pay particular attention to the modernization of higher education. In this regard, it is advisable to introduce lean technologies in the educational process of higher educational institutions, which will allow us to identify and develop the ability of these structures to self-development not only due to the influx of information and external finances, but through the use of their internal sources. The introduction of lean production principles in the activities of universities can help increase the efficiency of the educational process and their competitiveness. Based on this, the article discusses the process of lean manufacturing tool introduction into educational activities. An attempt is made to analyze comparatively lean manufacturing tools and the possibility of their application in the educational activities of the university. The article emphasizes that the replication of existing experience of lean manufacturing tool implementation will ensure a steady growth of key performance indicators and will allow the formation of a sustainable lean model of population behavior based on the popularization of the culture of “thrift” among students.
The determinant of sustainable consumption behaviour of Moslem woman in Sukoharjo
Authors: Prastiwi Septi Kurnia , Rabia Rabia
Published: December 2019

ABSTRACT

As the increasing of the public consumption pattern, it is followed by environmental pollution offset, which is increasingly alarming. This study aims to analyze how sustainable consumption behavior of Muslim women mediates the intention to behave. Two variables that are thought to influence the sustainable consumption behavior are environmental value and environmental sensitivity by mediating behavioral intention. This study uses a survey method with a population of Muslim mothers in the Sukoharjo area, a sample of 100 respondents, with sampling using a purposive technique, namely judgment sampling, and questionnaires with 12 indicator indicators. The results of the validity, reliability, and classical assumption tests support the continuing research. Results from the path analysis show that the variable â€˜environmental sensitivityâ€™ has a significant effect on behavioral intention and sustainable consumption behavior. Hypothesis test results show that environmental values â€‹â€‹have a positive and significant effect on behavioral intention and sustainable consumption behavior. The results of the sobel test show that behavioral intention can mediate the relationship between environmental values â€‹â€‹and the sustainable consumption behavior.
Tailoring the Weights on Objective versus Subjective Performance Measures between Top Management and Middle Managers: Evidence from Performance-Based Equity Incentive Plans
Authors: Chen Clara Xiaoling , Gao Yongjing , Wang Yue , Xue Shuang
Published: December 2019

This study examines the determinants of performance measurement tailoring between top management and middle managers in compensation contracts. Theoretically, while tailoring potentially enhances the informativeness of performance measures for top management and middle managers respectively, it may reduce the incentives for the two parties to coordinate with each other. We expect a firm's decision to tailor performance measurement between top management and middle managers to be driven by this cost-benefit trade-off. Using hand-collected data from performance-based equity incentive plans from Chinese public firms, we find evidence consistent with the predictions derived from our theoretical framework. Specifically, we find that the likelihood that a firm tailors the weights on objective versus subjective performance measures between top and middle managers increases with competition intensity, non-price competition, environmental uncertainty, and CEO power, and decreases with organizational stability and growth opportunity. Furthermore, we find that suboptimal tailoring decisions are associated with higher management turnover.
Principles of Ecology and Management
Authors: Sitkin Alan
Published: December 2019

or more than a decade now, business gurus have been advising managers to embark upon the kinds of environmental processes that will allow their companies to survive and thrive in the face of a mounting ecological imperative. The big question for students of business is therefore not why companies should go green, but rather why so little progress has been achieved so far. Hence the unique focus of this book, which turns the table on the cheerleading attitudes customarily associated with many green business texts to highlight instead the factors impeding the much desired transition towards greater corporate environmentalism. By gaining a more realistic understanding of these obstacles, readers will be able to develop a fuller sense of how they might be overcome.
There’s a new world coming: o dispensacionalismo pop nos quadrinhos
Authors: Rocha Daniel
Published: December 2019

O dispensacionalismo é uma perspectiva escatológica atribuída a John Nelson Darby e que ganhou popularidade nos Estados Unidos a partir da segunda metade do século XIX. Apesar do sucesso nos círculos conservadores que vinha desde o século XIX, foi na década de 1970 que o dispensacionalismo popularizou-se e suas crenças características, como o Arrebatamento dos crentes precedendo a Segunda Vinda de Jesus Cristo, tornaram-se conhecidas do grande público. O principal responsável por tal popularização foi o livro The Late Great Planet Earth de Hal Lindsey, lançado em 1970. O livro foi um sucesso absoluto de vendas e impulsionou uma indústria de publicações inspiradas pela perspectiva dispensacionalista. O dispensacionalismo pop se disseminou através de vários livros que buscavam interpretar o contexto geopolítico da época em uma chave dispensacionalista, mas também por meio de livros de “ficção apocalíptica”, de músicas, de filmes, de documentários e, também, de revistas em quadrinhos. Neste artigo analisaremos a revista There’s a New World Coming, publicada em 1974 e que levou para os quadrinhos a perspectiva de Hal Lindsey sobre o fim dos tempos.
“OLHEM, LÁ NO CÉU!” SUPERMAN E PROFETISMO JUDAICO
Authors: De Souza Viração Francisca Jaquelini
Published: December 2019

O presente artigo tem por objetivo fazer uma análise teológica e histórica do personagem Superman. A criação de Jerry Siegel e Joe Shuster apresenta paralelos claros com a história de Moisés e padrões que o aproximam dos antigos profetas judeus do Antigo Testamento. No entanto, Superman é um produto cultural que ao mesmo tempo é produtor e construtor de uma determinada época. Assim, o que será investigado é o Superman da Era de Ouro, caracterizada por histórias escritas pelos próprios criadores, para se perceber o quanto a Grande Depressão americana marcou a origem do personagem e como ele marcou as pessoas que vivenciaram esse período histórico. Desta feita, o artigo aborda as narrativas do Superman como fontes históricas ricas sobre a cultura do século XX propondo, inclusive, uma metodologia do trabalho que tem a história em quadrinhos como fonte para o estudo da história, então, perceber a teologia contida nessas histórias e a consequente razão do seu sucesso.
O elemento religioso no Surfista Prateado
Authors: Carvalho Romero Bittencourt e
Published: December 2019

Muitas histórias em quadrinhos estadunidenses são ricas em elementos religiosos, e a maior editora deste segmento, Marvel Comics, possui diversos personagens que flertam ou mesmo imergem neste campo. Destes, destaca-se o Surfista Prateado, personagem da dupla Stan Lee e Jack Kirby, que, desde 1966, discorre sobre a crueldade humana e sua incapacidade de viver em paz e harmonia. Neste artigo, apresento um resumo da trajetória deste icônico personagem nos quadrinhos, sobretudo de sua série original, de Stan Lee e John Buscema, suas indagações filosóficas e elementos religiosos, sobretudo do cristianismo e hinduísmo, presentes nas páginas.
KONSELING KELUARGA DENGAN HUMAN VALIDATION PROCESS MODEL MENINGKATKAN PROSOSIAL ANAK
Authors: Habibah Ummy
Published: December 2019

This journal is the result of research on family counseling through human validation process model to improve the low prosocial children in the family, so it could be a good attitude and behaviour. Reasearch method used qualitative approach with a case-study. This research sample is a child from a family. Instruments to collect the data are open-questionnaire, interviews and observation. This research results show that family counseling through human validation process model is given as a treatment is able tu increase prosocial’s child in the family. Key Word: family counseling (human validation process model), prosocial
Hubungan Interaksi Sosial Bentuk Akomodasi Guru-Siswa dengan Hasil Belajar Sosiologi Siswa SMAN 3 Padang
Authors: Efriman Efriman , Junaidi Junaidi
Published: December 2019

Penelitian ini dilatarbelakangi karena ketertarikan peneliti melihat hasil belajar siswa di SMA Negeri 3 Padang yang rendah akibat namun interaksi sosial yang terjadi antara guru dengan siswa berjalan dengan baik dan semestinya. Penelitian ini bertujuan untuk mengetahui hubungan antara interaksi sosial (akomodasi) dengan hasil belajar Sosiologi siswa SMA Negeri  3 Padang. Penelitian dianalisis dengan teori yang dikamukakan oleh Gegne dan Berliner. Di dalam penelitian ini digunakan suatu pendekatan kuantitaif Ex-Post Facto, teknik pemilihan proportional random sampling dan jumlah responden yang diambil 58 orang. Data sekunder dalam penelitian berupa hasil belajar dan dokumentasi yang dianalisis dengan menggunakan analisis data deskriptif data, pengumpulan data dilakukan dengan cara penyebarkan angket. Hasil dalam penelitian ini dapat dilihat bahwa terdapat yang signifikan dalam korelasi antara variabel interaksi sosial (akomodasi) dengan hasil belajar Sosiologi siswa SMA Negeri 3 Padang dibuktikan dengan koefisien korelasi (rxy) 0, 459 > rtabel 0, 256.
Genetic research of anadromous herring in Volga-Caspian fishery basin
Authors: Makarova Ekaterina Grigorievna , Kozlova Natalia Victorovna , Baregamyan Margarita Armenovna , Voinova Tatyana Victorovna
Published: December 2019

For the first time, a study of genetic variability of Caspian anadromous herring was carried out using molecular genetic methods. Sequencing of the cytochrome B site of mitochondrial DNA allowed to identify 7 haplotypes. The most massive haplotype was Hap_Alosa1 noted in 29 herring individuals. Five minor haplotypes were detected in few fish individuals. In the marine period of life in fish caught in the Northern Caspian there were noted rare haplotypes Hap_Alosa6 and Hap_Alosa7. In the river period of life in the Volga herring there was observed Hap_Alosa5. The revealed polymorphism of haplotypes was represented by single nucleotide substitutions. The genetic analysis of migratory herring does not give grounds for isolating the studied fish into separate groups. The marked low level of nucleotide diversity of cytochrome B gene of mitochondrial DNA of the anodromous herring indicates a significant genetic homogeneity of the species within the studied range. The results of analysis of nuclear DNA microsatellite loci showed that only three of the six sites of the studied gene were polymorphic. In individuals caught in the river period of life, only Af20 (out of the 6 loci studied) was polymorphic and was characterized by 4 alleles. In a sample of herring from the Northern Caspian, 3 polymorphic loci (Aa16, Af6 and Af20) were observed, in which 2 alleles were recorded. The observed heterozygosity varied from 0.313 to 0.667 exceeding the level of expected heterozygosity. In polymorphic loci a deficit of heterozygotes was not noted. The results obtained in this study indicate a low level of genetic variation of anadromous herring.
Güneydoğu Anadolu Bölgesinin Farklı Lokasyonlarından Toplanan Boynuzlu Geven (Astragalus hamosus L.) Otunun Bazı Kalite Özelliklerinin Belirlenmesi
Authors: BAŞBAĞ Mehmet , ÇAÇAN Erdal , SAYAR Mehmet Salih , FIRAT Mehmet
Published: December 2019

Bu çalışma, Güneydoğu Anadolu Bölgesinde yayılış
gösteren Astragalus hamosus L. türünün hayvanlar için
besleme değerlerinin tespit edilmesi ve lokasyonların benzerlik durumlarının
ortaya çıkarılması amacıyla yürütülmüştür. Araştırmada bitkisel materyal
olarak, Güneydoğu Anadolu Bölgesinin 20 değişik lokasyonundan toplanan Astragalus hamosus türüne ait bitkiler
kullanılmıştır. Astragalus hamosus
türüne ait bitkilerin kuru otlarında ham protein oranı, ADP (asit deterjanda
çözünmeyen protein), ADF (asit deterjanda çözünmeyen lif), NDF (nötral
deterjanda çözünmeyen lif), sindirilebilir kuru madde (SKM), kuru madde
tüketimi (KMT), nispi yem değeri (NYD), kalsiyum (Ca), magnezyum (Mg), fosfor
(P) ve potasyum (K) içerikleri belirlenmiş, yapılan istatiksel analizlerde,
incelenen bu özelliklerin tümü bakımından lokasyonlar arasında önemli farklılıklar
olduğu saptanmıştır. Araştırmadan elde edilen bulgular değerlendirildiğinde, Astragalus hamosus türünün ADF ve NDF oranlarının düşük, ham protein,
sindirilebilir kuru madde, kuru madde tüketimi ve nispi yem değerlerinin yüksek
ve ideal düzeyde olduğu görülmüştür. Kalsiyum, fosfor, potasyum, magnezyum ve
K:(Ca+Mg) oranlarının da istenilen düzeyde, ancak Ca:P oranının olması gereken
maksimum düzeyin (>2) üzerinde olduğu tespit edilmiştir. Lokasyonların
benzerlik durumlarını tespit etmek için kümeleme analizi yapılmıştır. Yapılan
kümeleme analizi neticesinde 20 farklı lokasyonun esasında dört gruba ayrılacak
şekilde varyasyon gösterdiği görülmüştür. İncelenen özellikler açısından
Diyarbakır-Ergani ve Mardin-Merkez lokasyonlarının birbirine en yakın, Diyarbakır-Merkez
(1) ile Şırnak-Cizre lokasyonların ise birbirine en uzak lokasyonlar olduğu
görülmüştür.
Ser Cyborg: Subjetividades Híbridas en el Capitalismo Cognitivo. Potencialidades y límites
Authors: Frachea María Tamara
Published: December 2019

Cada momento histórico se caracteriza por el alcance y desarrollo de sus medios de producción y a su vez permite la conformación de un tipo de subjetividad delimitada por el estadio de desarrollo de la sociedad en el cual se encuentra inserta. La actualización del capitalismo en su versión cognitiva se hace eco del alcance que tuvo el desarrollo de las nuevas formas de comunicaciones e información devenidas a partir de la revolución tecnológica de fines del siglo XX. Así, mientras las nuevas tecnologías, la información digital e internet forman parte del entorno social en el que estamos insertos en la actualidad, cabe preguntarse cómo son aplicadas por los dispositivos de control y cuáles son las posibilidades que nos ofrecen. El presente trabajo entrega una reflexión acerca del ser cyborg, un tipo de subjetividad que deviene en la aleación mente-software que se hace posible en la relación con los dispositivos que permiten el acceso a la información digitalizada. Así como las nuevas tecnologías permitieron afinar las técnicas de control del biopoder, es la figura del cyborg la que nos permite reflexionar acerca de nuevas formas de resistencia en la presente etapa del capitalismo cognitivo.
Tecnologías del capitalismo contemporáneo para el Entretenimiento y el Diseño de almas ¿estandarizadas?
Authors: Azcurra Mariani Ana Clara
Published: December 2019

En este trabajo nos proponemos un acercamiento exploratorio a las charlas TED (TED Talks), producto audiovisual alojado en la plataforma YouTube y la web ted.com de gran circulación y consumo. Frente a un actual régimen de acumulación flexible que parcela las voluntades y las responsabilidades vitales de manera individual, explorar críticamente las características de TED nos acerca a los patrones actitudinales actuales frente al conocimiento y la acción política.

TED parece ofrecer un producto a tono con el hedonismo nihilista al que se refiere Mark Fisher (2016), ese no pensar que se apropia de discursos rápidos y digeridos que permiten ostentar un supuesto conocimiento multidisciplinar e ilustrado. Una profundización en su formato puede iluminar intersecciones discursivas menos innovadoras de las que su apariencia indica, y lo suficientemente conservadoras en sus valores basales. En este sentido, el artículo se expande sobre cómo las famosas charlas funcionan como estructura en sintonía con las lógicas culturales del capitalismo contemporáneo, para luego avanzar sobre cómo incorporan a oradores que tensionan el formato por sostener lugares de enunciación y de origen subalternos.
Relaciones mediadas por tecnologías digitales. Reseña del libro Kentukis (2018, Random House) de Samanta Schweblin
Authors: Yansen Guillermina
Published: December 2019

Reseña del libro Kentukis (2018, Random House) de Samanta Schweblin.
Problemas geopolíticos y sociales en América Latina
Authors: Noemí. B. Mellado
Published: December 2019

Desde finales del siglo pasado se asiste a la reconfiguración y multiplicación de instancias de concertación, cooperación e integración; sin embargo, en la actualidad existen una serie de cuestionamientos y reclamos de índole social de diversa naturaleza.

Dichas demandas marcan la necesidad de establecer una agenda vinculada a materias que van desde una mayor equidad en la distribución del ingreso hasta el reconocimiento de derechos personales como la igualdad de género y la violencia hacia la mujer, generando replanteos en la gestión de los distintos niveles gubernamentales.
Att säga som det är
Authors: León Rosales René
Published: December 2019

In this article the author analyses how boys in upper secondary schools do identity work and masculinities mainly through verbally performing acts of both intolerance and tolerance in group discussions. The analytical focus highlights how both tolerance and intolerance are actualized in balancing acts that are based on an awareness of what is perceived to be linked to one or the other, and how identities are constructed through discursive resources and specific performances resulting in the production of masculinities. This performative balancing act is conceptualized as (in)tolerance as a masculine performance.
Combining product and packaging design for increased added value and customer satisfaction
Authors:   International Hellenic University, School of Science and Technology, Thermi, Greece, Vasileiadis Theoklitos , Tzotzis Anastasios ,   University of Zaragoza, Department of Design and Manufacturing Engineering, Zaragoza, Spain, Tzetzis Dimitrios ,   International Hellenic University, School of Science and Technology, Thermi, Greece, Kyratsis Panagiotis ,   University of Western Macedonia, Department of Industrial Design Engineering, Kila Kozani, Greece
Published: December 2019

Current paper shows an analysis of the conceptual design of products and packages that correspond to requested customer needs. A number of research tools, marketing/branding principles and product development techniques are presented. This study is an analytical demonstration of the whole design process from the concept to the final 3D rendered models with the use of a number of tools and methodologies i.e. mind maps, mood boards, sketches. In other words, it is a combination of marketing and designing principles that transformed the raw data received from customers into 3D CAD (Computer Aided Design) modeled products; a set of sportive sunglasses paired with a hand-watch from the same product family and a set of classic sunglasses with a casual hand watch. Finally, this project can be considered a blend between theoretical and practical methods that have been chosen and practiced after extensive research.