bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of CPR educational package on knowledge and performance of nurses working in intensive care units
Authors: Kuchaki Zeinab , Taheri Mostafa , Esfahani Hooman , Erfanifam Taher
Published: May 2022

Because nurses are present at the bedside of patients with cardiopulmonary arrest at the earliest opportunity, they should be sufficiently skilled in performing cardiopulmonary resuscitation (CPR). Since 1980s, several studies have been performed on the skill of CPR. These studies showed the effect of the presence of trained people on the outcome of resuscitation, so the results of one of these studies indicated that the presence of a more skilled person can have a dramatic effect on the outcome of resuscitation. Researchers believe that each training leads to learning, but the depth and stability of learning are different in various teaching methods. Recent Studies have examined the effectiveness of various educational programs in creating sustainable learning. One of the most common methods for teaching CPR is the workshop method, which has been used in nursing since 1941. Considering the importance of the subject and the need to study the effect of training courses on the level of knowledge and CPR performance of health care professionals, especially nurses, the present study aimed to review the effect of training package on knowledge and CPR performance of nurses working in intensive care units (ICU). A review of the literature showed that the level of knowledge and performance of nurses about CPR increased significantly after training compared to before training. However, most nurses perform CPR based on old protocols, it is necessary to express these changes during retraining courses. In addition, due to the decrease in the level of knowledge and skills, it is necessary to repeat these courses overtime.
Assessment of correlation of COVID-19 infection and periodontitis- A comparative study
Authors: Kaur Avineet , Sandhu Harnoor S. , Sarwal Aaron , Bhagat Shalika , Dodwad Reshma , Singh Gaganpreet , Gambhir Ramandeep S.
Published: May 2022

Background:

Periodontal disease constitutes a group of diseases involving inflammatory aspects of the host caused by several microbial agents that affect periodontal tissues and could have systemic implications.

Objective:

The present study was conducted to assess the correlation of COVID-19 infection and severity of periodontitis in subjects who has mild form of the disease as compared to subjects having moderate form of the disease.

Materials and Methods:

The study included 116 subjects suffering from COVID-19 that were equally divided into two groups, each based on a convenient sampling methodology. Group I had a moderate form of COVID that required hospitalization and Group II had a mild form of COVID and were treated at home. The stage of periodontal disease was assessed in both groups. Also, laboratory parameters such as level of C-reactive protein (CRP), white blood cell (WBC), D-dimer, vitamin D, and lymphocytes were also assessed. Statistical analysis was done using Chi-square and multiple logistic regression analysis.

Results:

More than 75% of subjects in both groups were non-smokers. Subjects having more than one comorbid condition were more in number in Group I (51.7%) as compared to Group II (24%). Severe periodontitis (stages 2–4) was found in 81% of subjects in Group I and 46.2% of subjects in Group II [Figure 1]. The odds of getting severe periodontal disease were 6.32 times more in subjects belonging to Group I as compared to Group II. Subjects having more than one comorbid condition were 4.43 times at risk of severe periodontitis as compared to subjects with no co-morbidity

Conclusion:

Severe form of periodontal disease was associated with moderate-to-severe COVID-19 infection and levels of lymphocytes, WBCs, and CRP were elevated in subjects belonging to Group I.
Epidemiological trend and clinical profile of COVID-19 patients
Authors: Sherwal Banke L. , Makkar Namrata , Jain Ajeet , Dogra Vikas , Prasad Shaleen , Jain Ragi , Gupta Aarti , Gulati Smita , Bhattar Sonali , Sharma Vikas , Saxena Shikhar , Das Payel , Bargotya Mona
Published: May 2022

Objective:

To study the epidemiological characteristics of the pandemic by describing the clinical profile of the COVID-19 patients presenting to a super specialty hospital

Methods:

This was a descriptive study using medical records of patients who tested positive for SARS-CoV-2 RNA using reverse transcription-polymerase chain reaction between 17th March and 15th January 2021 while maintaining confidentiality. The clinical and demographic data of all the patients were entered in a Microsoft Excel and statistical analysis was done using SPSS 21 software. Regression analysis was performed and a P value < 0.05 was considered to be statistically significant

Results:

A total of 3534 patients were enrolled in this study aged 9–96 years. Among patients with symptoms, fever and cough were the most common presenting symptoms, while 5.6% of the patients were asymptomatic. Hypertension was the most common comorbidity (37%), while no comorbidities were present in 43.0% of the participants and this was statistically significant for age (P = 0.000). Among patient outcomes, >50% of patients were in home isolation, while 11% of patients had a fatal outcome. Elder age group had a higher proportion of expiry among outcomes (P <= 0.001). Most patients had a hospital stay of 9–11 days. A total of 63 health workers were included with male: female ratio being 3.5:1

Conclusion:

Our study reflects that majority of the positive cases that presented to the hospital had mild/moderate symptoms. We believe that appropriate triaging of patients followed by early institution of medicine and good critical care services may help to control this epidemic.
Attitude, knowledge, and barriers towards research analysis and writing in Saudi Arabia
Authors: Albumijdad Jafar Radhi , Alismail Abdulmonem Saleh , Albesher Muslem Adel , Alhajri Abdulmohsin Mohammed
Published: May 2022

Background:

Conducting research requires the integration of certain levels of practice and knowledge, together with the right attitude. This study aimed to investigate the attitude, knowledge, and barriers regarding research analysis and writing among medical residents in Saudi Arabia

Methods:

This was an online-based cross-sectional study that was conducted in Saudi Arabia. Our targeted population was Saudi medical residents who were enrolled in the Saudi Commission for Health Specialties. Data were analyzed and compared to determine associations between the patients’ demographics and attitude, knowledge, and barriers

Results:

A total of 218 participants were ultimately included in the present study, with a mean age of 29 (± 2.6) years, and most participants (63.3%) had a previous research publication. Specialty and level of residency were the only significant factors that were associated with attitude (P = 0.023 and 0.046, respectively). Specialty and having previously published a research paper were the only factors that were associated with the knowledge scores (P = 0.001 and 0.0001, respectively). On the contrary, specialty was the only significant factor that was associated with barriers scores (P = 0.001). Regarding attitude scores, most residents (60.1%) had 26%–50%, while only 0.9% had >75% of the total score. Regarding knowledge scores, 38.1% of residents had ≤25% and only 7.8% had >75% of the total scores. Regarding barriers, most residents (73.4%) had 26%–50%, while none had >75% of the total scores

Conclusion:

Reduced awareness regarding research methodology in our population implies that further education measures should be undertaken.
Metabolic derangements with olanzapine and risperidone in schizophrenia spectrum and other psychotic disorders
Authors: Rikhari Praveen , Kumar Ashutosh , Agrawal Prabhat , Kumar Harendra
Published: May 2022

Background and Aims:

Schizophrenia spectrum and other psychotic disorders are common disorders often requiring long-term treatment with atypical antipsychotics, which might cause metabolic dysfunctions. We aimed to study the metabolic dysfunctions with olanzapine and risperidone in patients with schizophrenia spectrum and other psychotic disorders. We also explored the incidence of new-onset metabolic syndrome and its predictors

Methods:

This was a 24-week prospective observational study conducted at a teaching hospital in North India. The patients were prescribed olanzapine or risperidone. Anthropometric measurements (waist circumference, weight, body mass index, blood pressure) and biochemical investigations (triglycerides, high-density lipoproteins, fasting plasma glucose) were recorded at baseline and after 24 weeks. Metabolic syndrome was defined using the International Diabetes Federation definition. Statistical tests used were Fisher’s exact test, paired t-test, unpaired t-test, and logistic regression

Results:

A total of 45 patients, 30 on olanzapine and 15 on risperidone completed the study. Statistically significant changes occurred in all variables with olanzapine while with risperidone statistically significant changes occurred in all variables except waist circumference and fasting plasma glucose. Statistically greater changes in mean values between the two were noted only for high-density lipoprotein with olanzapine. 20% of patients developed metabolic syndrome with non-significant between drug differences. Baseline triglyceride predicted the development of the metabolic syndrome

Conclusions:

Olanzapine and risperidone cause metabolic derangements and statistically significant differences may not exist between them. Baseline triglyceride levels might predict subsequent metabolic syndrome.
Barriers to personal hygiene in persons with spinal cord injury during the COVID-19 pandemic and lockdown
Authors: Swarnakar Raktim , Santra Shreya , Yadav S. L.
Published: May 2022

Personal hygiene is the most important measure to prevent coronavirus disease 19 (COVID-19). The pandemic has put persons with disabilities into various challenges. People with spinal cord injury (SCI) are facing these obstacles more because of their altered physiology and increased susceptibility to COVID-19. Through telerehabilitation, hurdles were identified in two paraplegic individuals, such as safe water sources, concerns regarding self-catheterization, increased dependence on care partner, hygiene of assistive aids/wheelchairs, availability of dressing materials for pressure injury dressing, and sanitary pads for menstrual hygiene. To the best of our knowledge, these are the first cases to describe hygiene concerns of SCI people during the COVID-19 pandemic and its rehabilitation implications. Considering the population with disabilities, we should improve access to primary care at the community level regarding personal hygiene. For a large population with disabilities such as SCI who are at risk, simple health education, awareness, and economic ways of hygienic practices can be a saviour.
Effect of night shift on development of metabolic syndrome among health care workers
Authors: Bahinipati Jyotirmayee , Sarangi Rajlaxmi , Pathak Mona , Mohapatra Srikrushna
Published: May 2022

Circadian desynchronization, sleep deprivation, changes in eating habit, and lack of physical activity resulting in an increase in pro-inflammatory markers in night shift health care workers is associated with various risk factors for the development of metabolic syndrome. This study aimed to estimate the pro-inflammatory markers in night shift work and find its relationship with different criteria of metabolic syndrome.

Materials and Methods:

A total of 303 participants were recruited for the study. Demographic data and parameters pertaining to the development of metabolic syndrome were taken. Highly sensitive C-reactive protein (Hs CRP) as proinflammatory marker was analyzed. Fasting blood sugar (FBS), serum triglyceride (TG), and high-density lipoprotein (HDL) were estimated. Criteria for metabolic syndrome were taken according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guidelines.

Results:

Night shift workers had higher hs CRP compared to day shift workers. TG and FBS were increased significantly (P < 0.001). A total of 6.5% of the night shift workers had a waist circumference greater than 40 inches. It was observed that night shift workers with higher hsCRP had significantly high waist circumference (P < 0.001) and FBS (P < 0.05). A total of 3.57% of the night shift workers were diagnosed with metabolic syndrome with three criteria positive.

Conclusion:

Night shift work is associated with an increase in pro-inflammatory markers and the development of risk factors leading to metabolic syndrome. Thus, early screening and management of risk factors among night shift health care workers may improve their health status and prevent the development of MS.
Rhabdomyolysis triggered by azithromycin
Authors: Finsterer Josef , Stollberger Claudia C , Melichart-Kotig Madleine
Published: May 2022

A 17-year-old male with uneventful previous history developed generalized myalgias, exercise intolerance, and general fatigue after two dosages of azithromycin (500 mg/d) during 3 d for febrile infection. Neurologic exam revealed generally reduced tendon reflexes. Serum creatine kinase (CK) was elevated to 25000 U/L. Needle-EMG showed short and small, polyphasic motor-units and abnormal spontaneous activity, being interpreted as myositis. Azithromycin was discontinued and he was advised to avoid the fitness studio and to drink plenty of liquids. Myalgias disappeared within two days and CK continuously declined. Azithromycin may trigger rhabdomyolysis in the context of exercise and infection. Azithromycin may be myotoxic and should be prescribed with caution in exercising and infected patients.
A clinical study of fetal outcome following early and delayed cord clamping in births associated with anemia in pregnancy
Authors: Singh Lata , Singh Dhirendra P. , Deepika  , Raghunandan Chitra , Dhoat Navdeep
Published: May 2022

Background:

As there is a risk for infant anaemia, early cord clamping which is usually performed at 10-15 seconds of delivery was changed to delayed cord clamping for at least for 30 seconds Delayed cord clamping (DCC) increases the blood volume and haemoglobin levels in newborns and reduces risk of iron deficiency anaemia in both term and preterm infants.Early clamping allows cord blood collection in benefit for transplantation of stem cells.

Research Objective:

To compare levels of haemoglobin, hematocrit and serum ferritin at birth and 4 weeks of age in babies as well as neonatal outcome following early and delayed cord clamping in births associated with anaemia in pregnancy.

Study Design:

An observational study.

Participants:

Anaemic pregnant women with period of gestation 32-40 weeks admitted in labour room for delivery were enrolled. Intervention: Grouping of the patients was done according to the timing of the umbilical cord clamping. 1. Early cord clamping (< 60 seconds) 2. Delayed cord clamping (1 – 3 minutes) Of which 58 subjects were in ECC (early cord clamping)and 62 were in DCC (delayed cord clamping)group

Results:

There was no significance of ECC or DCC in developing polycythemia, IVH or hyperbilirubinemia or increased need of blood transfusion. The levels of haemoglobin, hematocrit and ferritin levels were showing significant increased among DCC as compared to ECC

Conclusion:

Delayed cord clamping significantly increases the levels of haemoglobin, Serum ferritin and hematocrit at 4 weeks of age. It should be recommended in routine practice where it is not contraindicated especially in resource- poor settings.
Prosthetic rehabilitation of resorbed mandible with two implant-supported overdentures using ball attachments
Authors: Varshney Krishna Kumar , Bhatia Vishwas
Published: May 2022

The aim of this study was to describe a technique of fabrication of two implant-supported mandibular overdentures. There are several treatment modalities for completely edentulous patients including conventional complete dentures (CDs), implant-supported overdentures (IODs), and implant-supported fixed prosthesis. Patients with a severely resorbed mandible often experience problems with their conventional CDs. Treatment concepts involving IODs have proven to be as satisfactory as implant-supported fixed prosthesis with added advantage of ease in hygiene maintenance and less cost. This clinical report summarizes a simplified and accurate method of fabricating two implant-supported mandibular overdentures. In this case, two implants were placed in the intercanine region of mandibular ridge and conventional CD was installed. Three months later, this CD was converted into implant-supported mandibular overdenture. Conventional CDs have shown less satisfaction rates by patients over a period of time in terms of function. Moreover, there are researches showing increased rate of resorption with these dentures. Thus, IODs are used routinely to provide a better quality of life to edentulous patients.
Presumed acute suppurative bacterial dacryoadenitis with concurrent severe acute respiratory syndrome coronavirus-2 infection
Authors: Almater Abdullah I. , Malaikah Rawan H. , Alzahrani Saeed , Al-Faky Yasser H.
Published: May 2022

Acute suppurative bacterial dacryoadenitis (ASBD) was not reported to occur following severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We are presenting a unique case of concurrent presumed ASBD with SARS-CoV-2 infection. A 23-year-old previously healthy male presented with right upper eyelid swelling and pain over the lacrimal gland area for 3 days. Before his visit, the patient was tested positive for SARS-CoV-2 infection after experiencing mild flu-like symptoms, despite being vaccinated 2 months ago. He was found to have clinical and radiological features highly suggestive of ASBD with concurrent SARS-CoV-2 infection. He was admitted and initiated on systemic and topical antibiotic, followed by incision and drainage of an abscess collection. The patient showed dramatic clinical improvement with no recurrent signs of infection during the follow-up period. This acute dacryoadenitis is presumed to represent a secondary bacterial infection possibly aided by immune-related factors that may coexist in SARS-CoV-2-positive patients.
Use of custom fabricated surgical jig to improve surgical outcomes in open reduction internal fixation of unilateral orbital fractures
Authors: Baviskar Padmakar S. , Natarajan Srivalli
Published: May 2022

PURPOSE:

The aim of the study was to assess the efficacy of virtual planning and surgical guide jig to improve surgical outcomes of open reduction and internal fixation with restoration and correction of orbital volume (OV) in unilateral orbital wall fractures.

METHODS:

Fifteen patients with unilateral orbital fractures were assessed with ophthalmologic and radiographic parameters. The orbit was divided into three zones on computed tomography to localize defects. Fractures were coded into Fx Mx Rx Lx (F = Orbital Floor, M = Medial Wall, L = Lateral wall, R = Orbital Roof) based on pattern and specific wall involved. 1-mm sections were used to make stereolithographic models, design the custom fabricated surgical jig for intraoperative use as a guide.

RESULTS:

Pre- and postoperative ophthalmological parameters, OV, were compared with the contralateral normal orbit serving as the reference. Postoperative ophthalmological parameters showed significant improvement in terms of visual acuity, enophthalmos, dystopia, and traumatic optic neuropathy. OV changes were concentrated in Zones 2 and 3. OV showed adequate restoration postoperatively.

CONCLUSION:

The surgical jig served as an efficient guide to improve surgical outcomes of open reduction internal fixation. Preplanned intraoperative positioning helped achieve adequate anatomical reduction and fixation with an adequate reconstruction of OV aiding the effective transfer of virtual surgical plan on the table with improved surgical outcomes in clinical performance and functional restitution.

Clinical trial registration: The Clinical Trials Registry of India (CTRI) Registration No.: CTRI/2019/11/021929.
Merkel cell carcinoma of the eyelid and periocular region
Authors: Walsh Noreen M.
Published: May 2022

Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine carcinoma with a high mortality rate. It typically affects elderly Caucasians, with a slight predilection for males. It is associated with chronic sun exposure and/or immunosuppression. Almost half of all cases occur on the head or neck and an estimated 2.5%–10% arise on the eyelids or periocular skin. It ranks as the 5th most common malignant tumor at these sites, preceded in frequency by basal cell, squamous cell and sebaceous carcinoma, as well as melanoma. Its clinical presentation as a violaceous nodule/plaque lacks specificity, and it can be mistaken for cysts, chalazia or basal cell carcinomas. Sub-specialized histopathological and immunohistochemical evaluations are required for diagnosis. Clinical staging defines the extent of disease and governs management. This includes surgery and adjuvant radiotherapy for localized tumors and of late, immunotherapy for metastatic disease. Significant advances in our understanding of the dual etiopathogenesis (Merkel cell polyomavirus- and Ultraviolet radiation-induced) and the biology of the neoplasm have been achieved in recent years. Issuing from the tumor's known susceptibility to host immunity, a recent therapeutic breakthrough has occurred whereby immune checkpoint inhibition has been shown to mitigate advanced disease. These factors and the increased global incidence of the tumor have brought it to the forefront of medical attention. This review provides a clinically relevant update on MCC, with special reference to cases arising on the eyelid/periocular region.
Self-regurgitation on pressure over lacrimal sac in cases of primary-acquired nasolacrimal duct obstruction
Authors: Alam Md. S. , Singh Parinita , Amitava Abadan K. , Ali Mohammad J.
Published: May 2022

PURPOSE:

To analyze the correlation between patient-reported regurgitation on pressure over lacrimal sac (ROPLAS) with the physician's examination in diagnosing primary-acquired nasolacrimal duct obstruction (PANDO).

METHODS:

A cross-sectional study was done over 5 months (March–July 2018). All cases diagnosed as PANDO were included in the study. The maneuver of pressing over the lacrimal sac area and noticing the egress of mucoid or clear fluid from the surrounding area by the patient was termed as self-ROPLAS. A specific patient history of performance of this maneuver was compared with a clinician-performed ROPLAS and subsequent objective lacrimal drainage evaluation. The various reasons for performing self-ROPLAS by the patients were documented.

RESULTS:

A total of 134 patients were included in the study, out of which 59 (44.02%) were males and 75 (55.9%) were females. History of self-ROPLAS was present in 64 (47.8%) of the patients, whereas the physician examination revealed ROPLAS to be positive in 92 (68.6%) of the patients. All patients (100%) with a positive history of self-ROPLAS had nasolacrimal duct obstruction on subsequent examination. The most common reason for performing self-ROPLAS was for emptying the discharge from the medial canthal region to reduce the painless swelling.

CONCLUSION:

Self-ROPLAS is highly suggestive of an obstructed nasolacrimal duct and can be used as a screening tool by the primary physician to triage the patients toward ophthalmic plastic clinics or consult.
Ocular adnexal metastases from renal cell carcinoma
Authors: Magan Tejal , Pradeep Tejus , Tuluc Madalina , Bilyk Jurij R. , Milman Tatyana
Published: May 2022

PURPOSE:

The purpose of this study was to review the clinical presentation, systemic work-up, and outcomes of all previously reported ocular adnexal (OA) metastases from renal cell carcinoma (RCC).

METHODS:

This was a literature review. PubMed and Google Scholar databases were searched for all well-documented cases of OA metastases from RCC.

RESULTS:

Final analysis identified 44 patients with either biopsy-confirmed (41/44, 93%) or treatment response-documented (3/44, 6%) OA metastases from RCC. Thirty-four (77%) patients were male. The median age was 60 years (mean: 60, range: 22–87 years). The most common presenting signs were proptosis (19/44, 43%) and OA mass (14/44, 32%). Metastases most frequently involved the orbital bones (10/44, 23%) and adjacent extraconal fat, extending from the sinonasal tract in 7/10 (70%) of these cases. OA metastases were initial manifestation of RCC in 18/44 (41%) patients. At the time of primary tumor diagnosis, 22 of 30 (73%) patients had American Joint Committee on Cancer Stage IV disease with metastases to 2 or more sites in 13 (57%) patients. Seventeen of 42 (40%) patients underwent local therapy only, which most commonly included excision/exenteration with margin control (10/17, 59%). Twenty-five of 42 (60%) patients had systemic therapy, which included biologic agents and chemotherapy. The absolute 5-year survival rate was 66% with significantly improved survival in patients reported after 2006 (92% vs. 42%, P = 0.04) and in those with isolated OA metastases (100% vs. 27%, P = 0.02) at 30 months.

CONCLUSION:

Although RCC metastases to OA occur in a setting of advanced disease, the recent advances in diagnostic modalities and targeted therapies resulted in improved survival.
Optical coherence tomography-guided early postoperative management of XEN Gel implant
Authors: Chen Yen-Cheng , Ko Yu-Chieh , Liu Catherine Jui-Ling
Published: May 2022

This interventional case series demonstrates the usefulness of anterior segment optical coherence tomography (AS-OCT) in guiding early postoperative management following XEN45 Gel Stent implantation, in conjunction with intraocular pressure (IOP) readings and slit lamp findings. Three primary open-angle glaucoma patients undergoing XEN45 Gel Stent implantation were included. Two patients received early postoperative needling because the IOP was not low enough and AS-OCT revealed that the XEN stent orifice was trapped by the Tenon's capsule. Immediately after needling, the distal tip of the XEN stent was freed and connected to a cystic space with significant IOP reduction. The third patient suffered from abrupt bleb flattening on the 5th postoperative day following XEN stent implantation. AS-OCT revealed internal occlusion of the XEN stent with exudative material, which resolved spontaneously after intensifying topical steroids with improved bleb functioning 2 days later. AS-OCT provides in-depth microscopic evaluation of the XEN stent and its relationship with surrounding tissue. This information is helpful in identifying causes of impaired outflow, determining the timing, and effect of needling intervention in eyes with inadequate bleb functioning or IOP control, especially during the early postoperative period.
Subretinal drusenoid deposits
Authors: Monge Manuel , Araya Adriana , Wu Lihteh
Published: May 2022

A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs), also known as reticular pseudodrusens, are located in the subretinal space, on top of the RPE. SDDs are poorly detected by clinical examination and color fundus photography. Multimodal imaging is required for their proper diagnosis. SDDs are topographically and functionally related to rods. SDDs cause a deep impairment in retinal sensitivity and dark adaptation. SDDs are dynamic structures that may grow, fuse with each other, or regress over time. An intermediate step in some eyes is the development of an acquired vitelliform lesion. The presence of SDD confers an eye a high risk for the development of late AMD. SDD leads to macular neovascularization, particularly type 3, geographic atrophy, and outer retinal atrophy.
Direct Oral Anticoagulants in Long-term Care Facilities: Rates of FDA-Approved Dosing
Authors: Whitney Benjamin , Sakel Katie , Lengel Aaron J.
Published: May 2022

Objective To determine rates of compliance with Food & Drug Administration (FDA)-approved dosing of direct oral anticoagulants (DOACs) in long-term care residents. Design A retrospective chart review of 90 patients, utilizing an electronic health record,
and a longterm care pharmacy’s dispensing record. Patient electronic health records were reviewed to collect the following data: prescribed DOAC, dose, therapy duration, diagnosis, age, height, weight, and serum creatinine. This information was used to determine the FDA-recommended DOAC
dose and recommended duration, which was compared with the prescribed dose and duration. Main Outcome Measure The rate of incorrect DOAC doses, defined as a discrepancy from the FDA-recommended dose, based on patient characteristics. Setting Two chains
of long-term care facilities in Michigan, Ohio, North Carolina, Tennessee, and Virginia serviced by a long-term care pharmacy. PATIENTS: Patients prescribed one of three targeted DOACs (apixaban, rivaroxaban, or dabigatran) between August and October 2019. Patients had to be a resident within
two long-term care chains. Results Thirty-three out of 90 residents were treated with an incorrect DOAC dose. This broke down into 20% of patients on a dose that was too low and 17% of patients on a dose that was too high. Conclusion The results of the
study identify the need for pharmacists to closely review the dosing of DOACs and recommend therapeutic changes based on treatment guidelines.
Semaglutide Initiation in a Type 2 Diabetes Mellitus, Post-Liver Transplant Patient
Authors: Newell Bradley J. , Melton Brittany L. , Burkhardt Crystal D. , Ruisinger Janelle F.
Published: May 2022

Objective To describe the process of initiation of semaglutide for complex management of type 2 diabetes mellitus (T2DM) in a patient after liver transplantation. Setting Family medicine clinic. Practice Description A family medicine
clinic comprising six physicians with an ambulatory care pharmacist. The pharmacist has direct interaction with patients and providers within the clinic assisting in the management of chronic disease states under a collaborative practice agreement. Practice Innovation A
63-year-old White male with a history of liver transplantation in the context of T2DM, treated with basal-bolus insulin therapy, was referred by his family medicine provider to the ambulatory care pharmacist for diabetes management because of a hemoglobin A1c (HbA1c) level greater than 10%.
Semaglutide was initiated and titrated to improve blood glucose control in combination with basal-bolus insulin adjustments taking disease states, cost, and health literacy into consideration. Results The addition of semaglutide, over an eight-month period, assisted with
glycemic control to an HbA1c of less than 7%. Conclusion Semaglutide, in addition to basal-bolus insulin therapy, allowed for overall improved glycemic control; however, further studies are needed to evaluate efficacy because of the complexity of diabetes management in
this patient population. Throughout the course of treatment of patients with T2DM and organ transplantation, dual monitoring of antidiabetic therapy and antirejection medications is essential to reduce the risk of organ rejection.
Urinary Tract Infections in Long-term Care: Evaluation of Uropathogens, Antibiotic Susceptibility, and Empiric Treatment
Authors: Bao Winnie , Koro Mira , Loh Gabriel W. , Ortiz Ana
Published: May 2022

Objective To devise a residential empiric treatment algorithm, describe common uropathogens associated with urinary tract infections (UTIs) in residential care, assess all-pathogen and non-ESBL (extended-spectrum beta-lactamase) Escherichia coli antibiotic susceptibilities,
and report the percentage of antibiotic use. Design A retrospective chart review of 198 residents with positive urine cultures from September 2019 to September 2020. Setting Institutional long-term care facility. Participants The
exclusion criteria were negative urine culture, mixed organisms on urine culture, no antibiotic treatment, signs and symptoms of systemic infection, hospitalization because of systemic infection, and intravenous antibiotic treatment. The entire population was screened. Results
The most prevalent pathogens were non-ESBL E. coli (29%), Proteus mirabilis (12%), Klebsiella pneumoniae (8%), and ESBL E. coli (8%). All-pathogen susceptibilities were 79.6% (amoxicillin/clavulanate), 64.1% (nitrofurantoin), 50.5% (sulfamethoxazole/trimethoprim), 43.7% (cephalexin),
42.7% (amoxicillin), and 41.8% (ciprofloxacin). Amoxicillin/clavulanate (96.7%), nitrofurantoin (90.0%) and sulfamethoxazole/trimethoprim (83.3%) demonstrated the highest non-ESBL E. coli susceptibilities. Nitrofurantoin was the most prescribed antibiotic (21%), followed by amoxicillin/clavulanate
(19%) and ciprofloxacin (17%). Conclusion Based on the data, amoxicillin/clavulanate and nitrofurantoin are appropriate first-line options for empiric treatment of symptomatic cystitis in this long-term care facility, with sulfamethoxazole/trimethoprim as an alternative.
Ciprofloxacin was overprescribed despite its low susceptibilities to commonly encountered pathogens, which emphasizes the need for a UTI empiric treatment algorithm tailored towards residential care.
Using Educational Social Networking Sites in Higher Education: Edmodo through the Lenses of Undergraduate Students
Authors: Çankaya Serkan , Durak Gürhan , Yünkül Eyüp
Published: May 2022

Social Networking Sites (SNSs) such as Facebook, Google+, MySpace, have been used intensively and effortlessly by students currently. Thus, the use of such SNS paves the way for questioning how these sites can be effectively used in educational environments. Since the SNSs in educational environments are potentially used, Educational Social Networking Sites (ESNSs) in the market such as Edmodo, Ning, Elgg, which are innovative educational environments with social networking capabilities, have also been employed in education. The aim of this study is to determine why the undergraduate students use the Internet, SNSs and Edmodo which is an ESNS and to investigate their views about these tools. In this context, Edmodo was used within the scope of an undergraduate course. And in order to collect data about this experience, interviews with 15 students and a focus group interview with 7 students were performed. In analysis and interpretation of the data used, both uses and gratifications theory and diffusions of innovations theory were taken into consideration. As a result, it was found that the students expressed their likes about Edmodo’s features of assignment, quiz, poll and announcement / sharing. The study also reveals that the students also expressed their thoughts about the contributions of Edmodo to educational environments.
A Comparative Investigation on the Wear Performance of Compacted Graphite Iron (CGI) Treated with Single and Double Tempering
Authors: TAN Engin
Published: May 2022

Compacted graphite iron (CGI) is a critical material in today's automotive and manufacturing industries. Heat treatment processes can improve CGI wear properties, related primarily to microstructural changes. In this study, single and double tempering heat treatments were used to improve the wear properties of CGI. Oil quenching was performed after 90 minutes of austenitization at 900°C, followed by 60 minutes of single and double tempering at three different temperatures (315, 350, and 375°C). The wear performance of the samples was compared using a pin-on disc test and hardness measurements. The volume loss and friction coefficient were evaluated, and wear maps were constructed to determine the samples' wear behavior. SEM and EDS analyses were carried out to worn surfaces to interpret the relationship between wear mechanism and microstructure. According to the study's findings, double tempering heat treatment may optimize wear performance better than traditional single tempering, and structures with high toughness-wear resistance combinations can be obtained.
Infrared spectroscopy chemometric model for determination of phenolic content of plant leaf powder
Authors: Wulandari Lestyo , Rahmadania Tyas Putri , Kristiningrum Nia
Published: May 2022

Introduction: The leaf is the part of the plant often used in traditional medicine because it is rich in one class of secondary metabolite compounds, namely phenolic compounds.   
Objectives: This study aims to establish a chemometric model for determining the phenolic content of plant leaf powders using the infrared spectroscopy (FTIR and NIR) method with a combination of chemometrics.   
Methods: The dried and powdered plant leaves were scanned using FTIR and NIR spectroscopy. Spectra were used to form calibration models. The calibration models were Partial Least Square (PLS), Principal Component Regression (PCR), and Support Vector Regression (SVR). The selected calibration model was validated using LOOCV and external cross-validation. The best calibration model was PCR, with R2 and RMSEC values of FTIR and NIR of 0.9918885; 0.9752648 and 0.8675906; 1.5150245, respectively.   
Results: The results of the Paired-Sample T-test analysis of actual samples determined by the selected calibration model compared to the comparison method showed no significant difference.
Identifying Strategies Used by Students to Manage their Emotions during Online Learning
Authors: Tengku Mahamad Tengku Elena , Mohd Azlan Nurul Atiqah , Rivadeneira Lucia
Published: May 2022

The coronavirus disease outbreak has disrupted the global economy on an unprecedented scale and speed and forced universities worldwide to abruptly adopt online teaching and learning. Although the concept of online learning is not new and that some universities possess the infrastructure to embrace online learning, many universities across the globe especially those in rural areas were largely unprepared to adapt to the new situation. Due to lack of preparation and many still being accustomed to traditional learning practices, the transition to online learning has taken an emotional toll not only on academics but also on their students. The present study aimed to understand the strategies students use to manage their emotions when engaged in online learning. Utilising a qualitative research method, we recruited 20 undergraduate students studying at a public university in Malaysia using the purposive sampling technique. Data were collected through semi-structured interviews conducted online. Thematic analysis revealed that some students experience fear, anger, and sorrow during online learning. These ‘difficult’ emotions can force the students to develop feelings of alienation and isolation and thus feel emotionally disconnected from their coursemates and lecturers. This is particularly due to the absence of in-person interactions compared to conventional face-to-face lectures. Furthermore, we found that the lack of verbal and non-verbal cues can cause students to lose motivation in learning. The findings of this study are expected to help academics and universities understand ways students cope with online learning and the need for their peers to help improve the students’ emotions.
O “Novo” em velhas práticas: uma análise sobre a noção de “Novíssimos” Movimentos Sociais e Coletivos
Authors: Santos Breno Augusto de Oliveira
Published: May 2022

Resumo
O artigo propõe refletir sobre a noção de “novíssimos” movimentos e coletivos a partir da literatura que os caracterizam como novidade em razão do uso das redes sociais, da não vinculação partidária, da horizontalidade e da noção de autonomia dessas organizações. Indagamos se as características dos “novíssimos” movimentos e os coletivos como novidade não se assemelham às de outros movimentos e grupos políticos em diferentes tempos históricos. Apresentaremos, dessa forma, um breve debate sobre os movimentos autônomos e a noção de autonomia a partir de eventos como maio de 1968 na França e Itália para analisar como alguns dos “novíssimos” movimentos e coletivos herdaram velhas práticas.

Palavra-Chave: novíssimo; autonomismo; maio de 1968.

Abstract

The article proposes to reflect on the notion of “brand new” movements and collectives from the literature that characterize them as novelty in the face of the use of social networks, the non-party linkage, horizontality and the notion of autonomy of these organizations. We asked if the characteristics of the “brand new” movements and collectives as a novelty and are not similar to other movements and political groups in different historical times. In this way, we will present a brief debate on autonomous movements and the notion of autonomy from events like May 68 in France and Italy to analyze how some of the “brand new” movements and collectives inherited old practices.

Keyword: brand new; autonomism; may 1968.

Resumen

El artículo propone reflexionar sobre la noción de “nuevíssimos” movimientos y colectivos de la literatura que los caracterizan como novedad por el uso de las redes sociales, la vinculación no partidista, la horizontalidad y la noción de autonomía de estas organizaciones. Preguntamos, nos preguntamos si las características de los “nuevíssimos” movimientos y colectivos y colectivos como novedad no son similares a otros movimientos y grupos políticos en diferentes épocas históricas. De esta manera, presentaremos un breve debate sobre los movimientos autónomos y la noción de autonomía frente a eventos como el de Mayo del 68 en Francia e Italia para analizar cómo algunos de los “nuevíssimos” movimientos y colectivos heredaron viejas prácticas.

Palabra clave: nuevíssimos; autonomismo; mayo del 1968.
Tempos fluidos com lembranças em conta gotas
Authors: Santos Douglas Manoel Antonio de Abreu Pestana
Published: May 2022

Crônica
Saudade da UFCA
Authors: Nascimento Ives Romero Tavares do
Published: May 2022

Poesia
Analytical and Theoretical Gravity Statistics
Authors: Liria Fabiana , Vintimilla Thyara , Vinueza Jadira Estefanía
Published: May 2022

In this work, a statistical analysis of the experimental values of gravity is carried out and they are contrasted with the existing theoretical values. To carry out the measurements, an experimental practice of the simple pendulum is carried out, which allows for obtaining data in a real way. Three-time measurements were made for each length of the pendulum, thus obtaining a broad data set. Descriptive statistics will facilitate the understanding of the analytical estimates of gravity, which will then be contrasted with the theoretical values. Finally, the results show that the percentage errors between the analytical gravity are acceptable with the theoretical values. The study of the simple pendulum with statistical analysis is a valuable engineering resource.
Low-Income Students, Human Development and Higher Education in South Africa: Opportunities, obstacles and outcomes
Authors: Walker Melanie , McLean Monica , Mathebula Mikateko , Mukwambo Patience
Published: May 2022

This book explores learning outcomes for low-income rural and township youth at five South African universities. The book is framed as a contribution to southern and Africa-centred scholarship, adapting Amartya Sen’s capability approach and a framework of key concepts: capabilities, functionings, context, conversion factors, poverty and agency to investigate opportunities and obstacles to achieved student outcomes. This approach allows a reimagining of ‘inclusive learning outcomes’ to encompass the multi-dimensional value of a university education and a plurality of valued cognitive and non-cognitive outcomes for students from low-income backgrounds whose experiences are strongly shaped by hardship.

Based on capability theorising and student voices, the book proposes for policy and practice a set of contextual higher education capability domains and corresponding functionings orientated to more justice and more equality for each person to have the opportunities to be and to do what they have reason to value. The book concludes that sufficient material resources are necessary to get into university and flourish while there; the benefits of a university education should be rich and multi-dimensional so that they can result in functionings in all areas of life as well as work and future study; the inequalities and exclusion of the labour market and pathways to further study must be addressed by wider economic and social policies for ‘inclusive learning outcomes’ to be meaningful; and that universities ought to be doing more to enable black working-class students to participate and succeed.

Low-Income Students, Human Development and Higher Education in South Africamakes an original contribution to capabilitarian scholarship: conceptually in theorising a South-based multi-dimensional student well-being higher education matrix and a rich reconceptualisation of learning outcomes, as well as empirically by conducting rigorous, longitudinal in-depth mixed-methods research on students’ lives and experiences in higher education in South Africa. The audience for the book includes higher education researchers, international capabilitarian scholars, practitioners and policy-makers.
Teacher Trainees‟ Perception of Indigenous Knowledge in Mathematics at Colleges of Education in Northern Ghana
Authors: yaw Osei
Published: May 2022

The continuous search for better ways of improving the teaching and learning of mathematics in schools leading to improved learning out comes on the part of learners have posed a great strain on mathematics educators in the 21st century. This paper examines the perceived indigenous knowledge in mathematics within the Colleges of Education in Northern Ghana. The survey design was adopted for the study. Population was made up of teacher trainees’ of Bagabaga, Tamale, St John Bosco and NJA colleges of Education. A sample size of 500 trainees was used for the study. Questionnaire was the main instrument used for data collection. Frequency counts and percentages and narratives were the main tools used for data analysis. It revealed that indigenous game (Man-to-Man) within the college communities contain concepts and skills in mathematics. It therefore recommended that mathematics teachers at the various colleges of education should tap and use these concepts during the teaching and learning of mathematics.
Các nhân tố tác động đến hoạt động sản xuất kinh doanh của Tập đoàn Dầu khí Việt Nam trong năm 2022
Authors: Nguyễn Hương Chi , Nguyễn Thị Thủy Tiên , Đặng Thanh Tùng , Nguyễn Anh Đức , Nguyễn Trung Khương
Published: May 2022

Quỹ Tiền tệ Quốc tế (IMF) đã giảm dự báo tăng trưởng GDP toàn cầu từ mức ước tính 6,1% (năm 2021) xuống mức 3,6% trong năm 2022 và 2023 [1]. Đặc biệt, Ngân hàng Thế giới (World Bank) dự báo xung đột giữa Liên bang Nga - Ukraine khiến giá năng lượng và phi năng lượng (lương thực và kim loại) trong năm 2022 tăng cao với mức tăng tương ứng là 50,5% và 19,2% [2].Trên cơ sở đánh giá tình hình kinh tế - chính trị thế giới và trong nước, bài báo phân tích các nhân tố tác động tới hoạt động sản xuất kinh doanh của Tập đoàn Dầu khí Việt Nam (Petrovietnam). Những nhân tố này vừa tác động tích cực, vừa tác động tiêu cực, vừa là cơ hội và vừa là thách thức cho Petrovietnam trong quá trình thực hiện mục tiêu, nhiệm vụ hàng năm, kế hoạch 5 năm 2021 - 2025 và Chiến lược phát triển đến năm 2030, tầm nhìn đến năm 2045.