bluuebunny/crossref_metadata_2025 huggingface dataset:
Highly Compact GCPW-Fed Multi-Branch Structure Multi-Band Antenna for Wireless Applications
Authors: Ahmad Ikhlas , Rehman Khan Wasi Ur , Ullah Sadiq , Mufti Naveed , Alharbi Abdullah G. , Hussain Niamat , Alibakhshikenari Mohammad , Dalarsson Mariana
Published: June 2022

In this work, we present a highly compact multi-branch structure multi-band antenna with a grounded coplanar waveguide (GCPW)-fed structure printed on 26 × 13 × 1.6

mm

3

sized FR-4 substrate having dielectric constant

ε

r

of 4.3 and loss tangent δ of 0.02. In the proposed antenna, five branches are extended from the main radiator to provide multi-band behavior. Two branches are introduced at the upper end of the main radiator, effectively covering the lower bands, while the other three branches are introduced near the center of the main radiator to extend operation to higher bands. The designed antenna covers five different bands: 2.4 GHz, 4.5 GHz, 5.5 GHz, 6.5 GHz, and 7.8 GHz, with respective gain values of 1.34, 1.60, 1.83, 1.80, and 3.50 dBi and respective radiation efficiency values of 90, 88, 84, 75, and 89%. The antenna shows a good impedance bandwidth, ranging from 170 MHz to 3070 MHz. The proposed antenna is simulated in CST Microwave Studio, while its performance is experimentally validated by the fabrication and testing process. The antenna has potential applications for IoT, sub-6 GHz 5G and WLAN (both enablers for IoT), C-band, and X-band services.
Design of a Multimedia-Assisted Distance English Teaching System for College Students
Authors: Feng Haili
Published: June 2022

To address the problems of poor compatibility, weak load capacity, and time consumption of existing multimedia-assisted teaching systems, we propose and design a physics multimedia-assisted English teaching system based on a concept network. The architecture of the physics multimedia-assisted teaching system is constructed with the logical layer as the core, and the theoretical knowledge module, experiment module, and student practice module are designed, respectively. Based on the concept network, a large number of rules in the physics teaching system are attached to the concepts to form the concept network knowledge system and complete the design of the theoretical knowledge system. This paper explores the multimedia teaching of college English and points out the advantages and characteristics of this teaching mode and the problems to be paid attention to in the process of application. The design of the physics multimedia-assisted teaching system is completed by realizing students’ practice and giving feedback on the practice results. The experimental results show that the system has good compatibility, strong load capacity, low time consumption, and practical application value.
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6
Authors: Xu Guang , Ma Tidong , Zhou Chonggao , Zhao Fan , Peng Kun , Li Bixiang
Published: June 2022

Background. Necrotizing enterocolitis (NEC) is a devastating disease affecting the gastrointestinal tract in the newborn period. In recent years, the role of apoptosis and autophagy in intestinal mucosal barrier dysfunction has come into prominence in research regarding the pathogenesis of NEC. β-Carotene is a well-known vitamin A precursor, and its content in breast milk is relatively high, especially in the colostrum. In the present study, we investigated the protective effect of β-carotene on necrotizing enterocolitis model cells IEC-6 induced by lipopolysaccharide (LPS). Methods. CCK-8 assay was performed to evaluate cell viability. The Annexin V-FITC/PI method was used to detect apoptosis. Western blotting was utilized to measure the expression levels of proteins. Immunofluorescence analysis was used to assess the autophagy of IEC-6 cells. Results. Our findings indicated that β-carotene inhibited the apoptosis of IEC-6 cells by downregulating cleaved caspase-3 levels and Bax levels and upregulating Bcl-2 levels, reducing cell autophagy via downregulating LC3II/I ratio and upregulating p62 levels. In addition, the expression of p-PI3K, p-AKT, and p-mTOR was upregulated after β-carotene treatment. Interestingly, these changes induced by β-carotene were partially reversed by rapamycin and voxtalisib. Conclusion. In conclusion, our findings indicated that β-carotene can attenuate apoptosis and autophagy of IEC-6 cells induced by LPS via activating the PI3K/AKT/mTOR signaling pathway. Therefore, β-carotene may be a promising drug used in the clinical treatment of NEC.
[Retracted] Preorder of Factors Affecting Oil Prices: Fuzzy PROMETHEE Approach
Authors: Abdullah Lazim , Harun Nurhatika , Mahali Shalela Mohd , Jan Naeem , Rak Ewa
Published: June 2022

Oil is a highly demanded worldwide product as oil prices can have a major economic and social impact. There are many factors affecting oil prices, but little is known about which factor mostly influenced oil prices. To understand what caused the fluctuation of oil prices, the investigation leading up to the identification of the factors must be constructed. Thus, this paper attempts to explore the factors that might have contributed to oil prices and analyze them using the fuzzy preference ranking organization method for enrichment evaluation (PROMETHEE) method. In particular, the objective of this study is to rank the influential factors affecting oil prices with the consideration of a few criteria. The fuzzy PROMETHEE model comprises four criteria and five factors as the input information. A group of four experts are invited to provide an evaluation on scales of 1 to 5 of the importance of factors with respect to criteria. In computation, the evaluations are treated as triangular fuzzy numbers in which the uncertainty in data is dealt with amicably. This approach combines the advantages of transformation equation and nonarithmetic mean of the defuzzification method that transforms triangular fuzzy numbers into crisp numbers. The results indicate that “supply and demand” is the most influential factor in determining oil prices. Comparative analysis and future research directions are also discussed at the end of this paper.
Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models
Authors: Bao Changlei , He Qian , Wang Hui , Sun Yanan , Xu Yahang , Pan Yan , Hu Yadan , Zheng Shichuang , Liang Shuxin , Luo Ang , Nahar Tanzilan , Chen Jiwang , Tang Haiyang , Han Ying
Published: June 2022

Background. Pulmonary arterial hypertension (PAH) is a complex pulmonary vasculature disease characterized by progressive obliteration of small pulmonary arteries and persistent increase in pulmonary vascular resistance, resulting in right heart failure and death if left untreated. Artemisinin (ARS) and its derivatives, which are common antimalarial drugs, have been found to possess a broad range of biological effects. Here, we sought to determine the therapeutic benefit and mechanism of ARS and its derivatives treatment in experimental pulmonary hypertension (PH) models. Methods. Isolated perfused/ventilated lung and isometric tension measurements in arteries were performed to test pulmonary vasoconstriction and relaxation. Monocrotaline (MCT) and hypoxia+Su5416 (SuHx) were administered to rats to induce severe PH. Evaluation methods of ARS treatment and its derivatives in animal models include echocardiography, hemodynamics measurement, and histological staining. In vitro, the effect of these drugs on proliferation, viability, and hypoxia-inducible factor 1α (HIF1α) was examined in human pulmonary arterial smooth muscle cells (hPASMCs). Results. ARS treatment attenuated pulmonary vasoconstriction induced by high K+ solution or alveolar hypoxia, decreased pulmonary artery (PA) basal vascular tension, improved acetylcholine- (ACh-) induced endothelial-dependent relaxation, increased endothelial nitric oxide (NO) synthase (eNOS) activity and NO levels, and decreased levels of NAD(P)H oxidase subunits (NOX2 and NOX4) expression, NAD(P)H oxidase activity, and reactive oxygen species (ROS) levels of pulmonary arteries (PAs) in MCT-PH rats. NOS inhibitor, L-NAME, abrogated the effects of ARS on PA constriction and relaxation. Furthermore, chronic application of both ARS and its derivative dihydroartemisinin (DHA) attenuated right ventricular systolic pressure (RVSP), Fulton index (right ventricular hypertrophy), and vascular remodeling of PAs in the two rat PH models. In addition, DHA inhibited proliferation and migration of hypoxia-induced PASMCs. Conclusions. In conclusion, these results indicate that treatment with ARS or DHA can inhibit PA vasoconstriction, PASMC proliferation and migration, and vascular remodeling, as well as improve PA endothelium-dependent relaxation, and eventually attenuate the development and progression of PH. These effects might be achieved by decreasing NAD(P)H oxidase generated ROS production and increasing eNOS activation to release NO in PAs. ARS and its derivatives might have the potential to be novel drugs for the treatment of PH.
Prediction Model of International Trade Risk Based on Stochastic Time-Series Neural Network
Authors: Xu Lei , Dong Guicai
Published: June 2022

With the extreme deterioration of domestic and foreign trade environment, international competition is becoming increasingly fierce. At the same time, many enterprises have loopholes in industrial structure and finance, resulting in many risks in their international trade. Therefore, we must take corresponding measures to effectively manage and avoid risks and realize the healthy and sustainable development of foreign trade enterprises and enterprise economy. This paper designs and proposes a risk prediction model combining ARIMA and BP neural network. The model can get good prediction in different time series and effectively avoid the risk. The model proposed in this paper optimizes the structure of the design model with the support of ARIMA algorithm and BP neural network algorithm and has good accuracy and error control for different time series. The purpose of establishing time series prediction model is to improve the prediction accuracy of the model, and it is also an effective way to enhance the practicability of the prediction model. Applying intersequence analysis method to financial risk prediction can greatly improve efficiency and save cost and has broad application prospects.
Application of Metal Oxides Prepared Based on Ferroelectric‐Based Photoelectric Conversion Materials in the Thermal Degradation of Polybrominated Diphenyl Ethers
Authors: Gao Lan , Li Min , Huo Lijing , Zhang Pengfei
Published: June 2022

In today’s environment where the society attaches great importance to environmental pollution, there has been a certain amount of research at home and abroad to explore the solutions to pollution of the large amount of polluting and persistent harmful substances that remain in nature. And most people think that it is necessary to solve the problem of pollution in two ways. (1) Energy: without discussing other energy sources, we will only discuss the main oil of today’s energy. The treatment and use of this energy will cause pollution to a certain degree, and it has been overexploited. The exploration of new energy sources and increasing the use of natural energy such as wind and solar energy are the main research directions today. (2) Degradation of existing pollutants: nowadays, due to the rapid development of various industries, attention to environmental pollution has reached a point that cannot be ignored. As a kind of brominated flame retardant, polybrominated diphenyl ethers are widely used because of their low price and stable chemical properties, mostly in electronic appliances, building materials, textiles, furniture, and other products. But the substance is extremely harmful. This article focuses on the degradation treatment of tetrabromodiphenyl ether, which is one of the polybrominated diphenyl ethers that are long‐lasting and difficult to be degraded in the environment. It has become an emerging persistent organic pollutant due to its toxicity, persistence, and bioaccumulation. Based on the reduction and debromination of zero‐valent iron, the effect of debromination of tetrabromodiphenyl ether is explored under the coupling effect of the nanosized iron powder with the smaller particles of zero‐valent iron and vitamin B12. The experimental results in this paper show that when the dosage of nanoiron powder is between 0.0 g/L and 0.15 g/L, according to the degradation diagram, the reaction rate is continuously strengthened with the increase of nanoiron powder. When the dosage of nanoiron powder is 0.15 g/L‐1.0 g/L, the effect will be weakened with the increase of the concentration. Therefore, an increase in the concentration of nanoiron powder will promote the progress of the debromination reaction. But when it reaches a certain level, the reaction rate will gradually decrease until it stops.
[Retracted] An Ideal Approach for Enhancing 5‐Fluorouracil Anticancer Efficacy by Nanoemulsion for Cytotoxicity against a Human Hepatoma Cell Line (HepG2 Cells)
Authors: Mohamed Jamal Moideen Muthu , Ahamad Fazil , El-Sherbiny Mohamed , Ebrahim Hasnaa Ali , Eladl Mohamed Ahmed , Dawood Amal F. , Khader S. T. Sheik Abdul , Kavitha Karuppaiyan , Teressa Dawit Mamiru
Published: June 2022

The core objectives of the research were to prepare 5‐fluorouracil nanoemulsion (FU‐NE) and to evaluate the physiochemical properties and to study the in vitro antiproliferation in HepG2 cell lines. The physiochemical parameters determined were compatibility, particle size (PS), polydispersity index (PDI), zeta potential (ZP), density, surface tension (ST), pH, viscosity, in vitro release of FU, cytotoxicity, and apoptosis study. The prepared FU‐NE3 was stable, sterile, and homogeneous. On the HepG2 (120 μg.mL-1) cells, in vitro cytotoxicity was obtained at IC50 concentration. Apoptosis examination by AO/EBand Hoechst staining shows that the majority of cell demise was caused by apoptosis, with a tiny fraction of necrosis. Hence, this investigation concluded that the developed FU‐NE has now desirable characteristics for drug delivery to the cancer cell and may be screened for the in vivo colorectal anticancer activity.
The Function Mechanism of the Current Situation of Chinese Cultural Integration and Environment on the Development of Chinese Enterprises
Authors: Zhang Shuwen
Published: June 2022

China’s economy is booming and many Chinese enterprises are growing rapidly. The report card handed over by Chinese enterprises through practical actions proves that Chinese outstanding entrepreneurs have successful modern management experience. These Chinese entrepreneurs have experienced the test of practice, and the experience gained has Chinese characteristics and is worth promoting. Entrepreneurs carry out more business management practices, which also provides valuable reference resources for the study of Chinese management thought. At the same time, The Times is also calling for more Chinese entrepreneurs to form their own management ideas. The influence of the current situation of the Chinese cultural integration environment on the development of Chinese enterprises is mainly that a good cultural integration environment will promote the development of enterprises and provide preconditions for the development of Chinese enterprises. This paper studies the current situation of Chinese culture integration environment of Chinese entrepreneur management thought formation process; the main purpose is, through the analysis of Chinese outstanding entrepreneur management thought formation process, to reveal the Chinese culture integration management environment formation law and essential characteristics, in order to enrich the management cognitive research and Chinese entrepreneurs management thought research, publicity, and promotion of Chinese outstanding entrepreneurs form management thought and also to provide a reference for more practitioners.
Effect Evaluation of Comfort Nursing Materials Assisted Nursing for Patients with Advanced Malignant Tumor
Authors: Zhong Mei , He Lanying , Chen Min , Lu Zhongxiang , Li Ruyu , Li Ling
Published: June 2022

In order to explore the effect of comfort care on patients with advanced malignant tumors assisted by bioceramics, 82 patients with advanced malignant tumors admitted to a cancer hospital were selected as the research object control group: 26 males and 15 females and the observation group: 25 males and 16 females. The control group was given routine care, and the observation group was given comfort care on the basis of the control group. The quality of life (QLQ-C30 functional scale) and nursing satisfaction before and after nursing were compared between the two groups. The results of the study indicate that after care, the physical, role, emotional, cognitive, social, general health, and symptom scores of the observation group were significantly higher than those of the control group, the nursing satisfaction degree of the observation group was 97.56%, which was significantly higher than that of the control group of 82.93%, and the difference was statistically significant (

P
<
0.05

). Comfortable care has a definite effect on the care of patients with advanced malignant tumors; it can improve the overall comfort and satisfaction of patients, effectively reduce adverse events, and improve the quality of life of patients.
Existence of Fixed Points for a Class of Decreasing Operators with Parameter and Applications
Authors: Li Xingchang , Tian Shiqin
Published: June 2022

This paper studies the existence of fixed points for a class of decreasing operators with parameter in real Banach spaces. The existence theorems of fixed point are obtained as when the parameter is increasing, there will still be a large fixed point. These results have reduced the requirements of convexity, compactness, and lattice structure of spaces. By this new method, the existence of solutions for a class of second‐order differential equations with parameter in infinite intervals is studied.
Model Test of the Water and Sand Mixture Inrush in the Mining-Induced Caving Zone
Authors: Liang Yankun , Zhang Chaoli , Wang Wenxue , Shen Xiangyang , Jia Minghui
Published: June 2022

In western China coal mines, the mining-induced caving zone is regarded as a main pathway for water and sand inrush mixture hazards. The paper experimentally studied the flow behavior and the mechanism of water and sand mixture through mining-induced caving zones. Transport experiments are performed by using a laboratory-scale model, and the caving zone is modelled by using different sizes of glass beads. Four different sand sizes are used for the sand layer. The test results reveal that the mass flow rate of sand and water mixture increases with the increase of the initial water head. And an equation is proposed for the mass flow rate of sand and water mixtures that correctly reproduces the data for all the conditions. In addition, the sudden decreases in water head loss is monitored at the commencement of the water and sand flow, which would result in a large number of sand particles that rapidly start up and make the kinetic energy transfer from water to sand.
Reconstruction of Traditional Village Spatial Texture Based on Parametric Analysis
Authors: Li Jiulin , Chu Jinlong , Wang Yongzheng , Ma Min , Yang Xingang
Published: June 2022

Chinese traditional villages, as the space carriers of Chinese excellent traditional culture, are a nonrenewable cultural heritage with rich value connotations. The primary consideration for the protection of the authenticity of traditional villages as a historical and cultural heritage is the continuation of spatial authenticity. The inheritance and shaping of traditional characteristics requires the study of the laws of traditional villages’ spatial form. Spatial texture is an important landscape resource for traditional villages, and it is also a space carrier to display and carry the historical and cultural characteristics of the village. However, the current practice of village planning and construction has destroyed this original spatial texture, resulting in a rupture of the inheritance of traditional characteristics of village space. The fundamental reason lies in the lack of emphasis on the subjectivity and regularity of village space and the lack of quantitative analysis and planning application of the inherent laws of spatial texture. Based on the integration of inheritance and transformation, this research proposes to use the advantages of digitization, visualization, and dynamics in parametric technology to quantitatively analyze the internal laws of the village spatial texture and assist the planning and design of the village spatial texture, in order to effectively promote the benign inheritance and optimization of the traditional characteristics of the village spatial texture which makes the planned spatial texture both traditional and modern. The research results show that (1) the parametric-based planning technology can better analyze the existing laws of the village spatial texture in a comprehensive, quantitative, and precise manner. (2) The parametric technology has a relatively high value in the planning and design of the village spatial texture. Due to strong applicability, it can invert the spatial form of the village and optimize the planning scheme by adjusting parameters and rules. (3) Although the parametric planning and design party has certain artificial intelligence, it cannot completely replace the human brain. The planning scheme generated by the method cannot be directly applied but can be used to assist the design scheme. It needs to be adjusted and corrected via the subjective initiative of people and wider participation.
Analysis of Multiinterface Autonomous Moral Learning Platform Based on Intelligent Computing
Authors: Chai Siyu , Meng Lingyi , Wu Shangzhuo , Song Chao , Li Heti
Published: June 2022

In order to realize the self-learning of the platform, an improved RBF neural network model is adopted, and a similarity matching algorithm is added, which improves the comfort of platform users and reduces redundant knowledge links. Based on constructivism, platform moral education constructs an intelligent computing learning platform with autonomous learning function through the construction mode. Based on the relatively perfect database, the moral learning platform extracts relevant resources for the platform teaching mode and basic services respectively, so as to optimize the platform design. Rely on computer technology to establish educational resource database, extract or collect teaching resources from all aspects, and form a database group with complete information. After the platform content design is completed, different interfaces are used to link to different end users. The establishment of multi-interface can make the system online at different terminals, fully consider the user’s moral learning environment, and let users learn online anytime and anywhere. Compared with the traditional algorithm, the improved algorithm adds the similar matching function on the basis of RBF algorithm. It reduces the phenomenon of repeated push in students’ autonomous learning system. The similarity matching algorithm is added to improve the comfort of platform users and reduce the redundant knowledge chain. The construction of moral learning teaching mode not only increases the interaction of the platform, but also improves the efficiency of user education and learning, and enhances the user’s awareness of intelligent computing.
Construction of Nursing Practice Model in Case Management of Concurrent Chemotherapy and Radiochemotherapy Treatment in Cervical Cancer
Authors: Tang Liqin , Xing Yan , Li Hui
Published: June 2022

Objective. To construct a case management model of synchronous radiotherapy and concurrent chemotherapy and radiochemotherapy (CRR) for cervical cancer led by nurses and carry out preliminary implementation and evaluation, so as to explore a new model of nursing practice. Methods. Totally 80 cervical cancer patients were included in this study, 43 patients were in the experimental group, and 37 patients were in the control group. The clinical data, side effects, psychological reactions, and nutritional indexes were collected before and after the intervention. Results. The results of Hospital Anxiety and Depression Scale (HADs) showed that anxiety and depression scores decreased after intervention in the experimental group, and the difference between two groups had significant after intervention (

P
<
0.05

). Serum fatty acids, albumin, and cholesterol in the experimental group were decreased after the intervention. Moreover, the incidence of radiation vaginitis and radiation dermatitis had significant differences between the two groups (

P
<
0.05

). Conclusion. The case management nursing practice mode of concurrent radiotherapy and chemotherapy for cervical cancer can effectively promote the self-management of risk factors, reduce the occurrence of complications, and improve the ability of self-care.
Clinical Outcomes of Cannulated Screws versus Ring Pin versus K‐Wire with Tension Band Fixation Techniques in the Treatment of Transverse Patellar Fractures: A Case‐Control Study with Minimum 2‐Year Follow‐Up
Authors: Liu Junchuan , Ge Yiming , Zhang Guolei , Zheng Xuehong , Gao Liang , Xing Enzeng , Lu Jiangfeng , Di Jun , Guo Junfei
Published: June 2022

Purpose. K‐wire with tension band (KTB) technique has long been the primary surgical method for transverse patella fractures; however, it also has shortcomings. This study is aimed at evaluating the three different techniques to see whether the cannulated screw tension band (CSTB) or ring pin tension band (RPTB) techniques could decrease complications and achieve better knee function compared with KTB. Methods. We conducted a retrospective comparison of the KTB, CSTB, and RPTB fixation techniques. We selected and reviewed 90 patients (30 patients in each fixation group) with follow‐up at least 2 years. Duration of operation, intraoperative blood loss, mean healing time, visual analog scale score, range of motion, Böstman score, Iowa knee score, modified Lysholm rating scale, and postoperative complications were compared. Multivariate analyses were performed to identify the independent risk factors for fracture healing time, postoperative complications, and knee function recovery. Results. After adjusting for confounding factors, multivariate regression analysis revealed that CSTB was 0.26 times (95% CI: 0.08‐0.86, p = 0.027) less likely to prolong fracture healing time, 0.20 times (95% CI: 0.06‐0.64, p = 0.007) lesser risk of postoperative complications, and more than four times (95% CI: 1.41‐13.56, p = 0.011) as likely to improve the knee function score compared with KTB. Besides, RPTB were also superior to KTB in reducing the incidence of postoperative complications (OR: 0.21, 95% CI: 0.07‐0.64, p = 0.006) and improved knee function score (OR: 3.96, 95% CI: 1.30‐12.08, p = 0.016); however, the CSTB group being more superior. In addition, AO/OTA C2 fractures (OR, odds ratio: 10.68, 95% CI: 1.30‐87.70, p = 0.027) and high‐energy fracture (OR: 8.78, 95% CI: 1.57‐49.17, p = 0.013) were also associated with prolonged fracture healing time but not with postoperative complications and knee function. No significant differences in related indicators such as gender, age, BMI, AO/OTA classification, fracture side, injury mechanism, duration of operation, and intraoperative blood loss were detected among the three groups. Conclusion. This study demonstrated that the CSTB technique is superior to KTB and RPTB techniques in reducing the incidence of postoperative complications, and it also has advantages in accelerating fracture healing, achieving better VAS, ROM, and functional recovery. Further long‐term large‐sized prospective randomized trials are needed to evaluate the efficacy of the KTB in treating transverse patellar fractures.
Discriminating the Pneumonia-Positive Images from COVID-19-Positive Images Using an Integrated Convolutional Neural Network
Authors: D Vetrithangam , Indira V. , Umar Syed , Pant Bhaskar , Goyal Mayank Kumar , B Arunadevi
Published: June 2022

One of the most pressing issues in the current COVID-19 pandemic is the early detection and diagnosis of COVID-19, as well as the precise separation of non-COVID-19 cases at the lowest possible cost and during the disease's early stages. Deep learning-based models have the potential to provide an accurate and efficient approach for the identification and diagnosis of COVID-19, with considerable increases in sensitivity, specificity, and accuracy when used in the processing of modalities. COVID-19 illness is difficult to detect and recognize since it is comparable to pneumonia. The main objective of this study is to distinguish between COVID-19-positive images and pneumonia-positive images. We have proposed an integrated convolutional neural network focused on discriminating against COVID-19-infected patients and pneumonia patients. Preprocessing is done on the image datasets. The novelty of this research work is to differentiate the COVID-19 images from the pneumonia images. It will help the medical experts in the decision-making. In order to train the model, the image is given directly as input to integrated convolutional neural network architecture; after training the model, the system is integrated with three different kinds of datasets: COVID-19 image dataset, RSNA pneumonia dataset, and a new dataset created from COVID-19 image dataset. The attainment of the system is evaluated by calculating the measures of sensitivity, specificity, precision, and accuracy, and this system produces the accuracy values of 94.04%, 97.2%, and 97.5% for the above datasets, respectively.
Optical Resolution Photoacoustic Microscopy Imaging in the Detection of Early Oral Cancer under Image Reconstruction Algorithm
Authors: Zhang Liyuan , Wang Xiaopeng
Published: June 2022

This research was intended to explore the application value of photoacoustic imaging technology based on image intelligent iterative reconstruction algorithm in the detection and diagnosis of early oral cancer. An iterative algorithm model was constructed and systematically analyzed. The algorithm was used to debug the detection of B-scan images on the diameter of the imaging area. The results showed that the sensitivity of line-focused ultrasound detector was 86.72% and the specificity was 80.79%, while the sensitivity of the flat-field ultrasound detector was 63.15% and the specificity was 71.79%. The photoacoustic microscopy imaging technology can clearly observe the rich capillary network on human lips. A part of the vascular network at the depth of 100 μm, 500 μm, and 1000 μm grew out of the reticular capillaries and extended out of the loop-like capillaries, and the diameter gradually expanded. The imaging experiment of the sublingual capillary network in the human body showed that loop-like capillaries were observed, but there were some large blood vessels, which corresponded to the densely distributed blood vessel network under the tongue. The morphological changes of loop-like capillaries can be well observed by photoacoustic microscopy. In conclusion, the reconstructed photoacoustic microscopy imaging technology can realize high-resolution imaging of human oral capillaries and observe the morphological changes of loop-like capillaries, which had a certain application value for the early detection of oral cancer.
Investigation of Atom-Bond Connectivity Indices of Line Graphs Using Subdivision Approach
Authors: Husin Mohamad Nazri , Zafar Sohail , Gobithaasan R. U.
Published: June 2022

A topological index is a numerical measure that characterises the whole structure of a graph. Based on vertex degrees, the idea of an atom-bond connectivity

A
B
C

index was introduced in chemical graph theory. Later, different versions of the ABC index were created, and some of these indices were recently designed. In this paper, we present the edge version of the atom-bond connectivity

A
B

C

e

index, edge version of the multiplicative atom-bond connectivity

A
B
C
I

I

e

index, and atom-bond connectivity temperature (

A

B

C

T

) index for the line graph of subdivision graph of tadpole graph

T

n
,
k

, ladder graph

L

n

, and wheel graph

W

n
+
1

. Numerical simulation has also been shown for some novel families of atom-bond connectivity index comparing the three types of indices which can be useful for QSAR and QSPR studies.
Angiotensin II Mediates Cardiomyocyte Hypertrophy in Atrial Cardiomyopathy via Epigenetic Transcriptional Regulation
Authors: Zheng Liuying , Wang Jin , Zhang Rui , Zhang Yingyi , Geng Jie , Cao Lu , Zhao Xiaoyun , Geng Jianhui , Du Xinping , Hu Yuecheng , Cong Hongliang
Published: June 2022

Aims. European Heart Rhythm Association established an expert consensus to define, characterize, and classify atrial cardiomyopathy into four subgroups based on their histopathological features. The predominant pathological feature of classes I and III is the hypertrophy of atrial cardiomyocytes. Here, we aim to investigate the mechanism of epigenetic transcriptional regulation of cardiomyocyte hypertrophy in atrial cardiomyopathy. Methods and Results. Compared with that of sinus rhythm control individuals, the myocardium of patients with atrial fibrillation exhibited increased levels of angiotensin II (AngII), chromatin-bound myocyte enhancer factor 2 (MEF2), acetylated histone H4 (H4ac), and H3K27ac; upregulation of hypertrophy-related genes; and decreased levels of histone deacetylase (HDAC) 4 and HDAC5 bound to the promoters of hypertrophy-related genes. Furthermore, incubation of atrial cardiomyocytes with AngII increased their cross-sectional area and improved the expression of hypertrophy-related genes. AngII also promoted the phosphorylation of HDAC4 and HDAC5 and induced their nuclear export. RNA sequencing analyses revealed that AngII significantly upregulated genes associated with cardiac hypertrophy. Chromatin immunoprecipitation showed that this correlated with increased levels of chromatin-bound MEF2, H4ac, and H3K27ac and decreased HDAC4 and HDAC5 enrichment in the promoters of hypertrophy-related genes. Moreover, these AngII-induced prohypertrophic effects could be partially reverted by treatment with the AngII receptor blocker losartan. Conclusions. AngII had a prohypertrophic effect on atrial cardiomyopathy which was epigenetic-dependent. Patients with atrial fibrillation manifest an increased susceptibility to hypertrophy and exhibit epigenetic characteristics that are permissive for the transcription of hypertrophy-related genes. AngII induces histone acetylation via the cytoplasmic-nuclear shuttling of HDACs, which constitutes a novel mechanism of atrial hypertrophy regulation and might provide a promising therapeutic strategy for atrial cardiomyopathy.
Analysis of the Impact of Equity Incentive on Performance Management Based on Balanced Integral Method
Authors: Zhou Na , Dong Kunjing , Guo Hao , Yang Congshang
Published: June 2022

Improving the equity incentive system has a certain role in promoting the development of the company, but at present, there are relatively few studies on the equity incentive methods of listed companies under the balanced scorecard theory. This paper analyzes the role of equity incentive method of D listed company in enterprise performance management through the balanced scorecard theory and constructs an enterprise financial management evaluation system with qualitative and quantitative characteristics. The evaluation system includes five target layers, two dimensions, and 27 evaluation indicators. The results show that the number of researchers, the number of graduate students, market share, management fee rate, the number of chip patent applications and other internal business processes, customers, and learning and growth are better. Before the implementation of equity incentive method, the evaluation value range of primary indicators is 6–8 points. After the implementation of equity incentive method, the evaluation value range of primary indicators is 2–6 points. This study analyzes the impact of equity incentive methods on performance management through the balanced integral method, which has high application value in subsequent enterprise financial management and risk assessment.
Simple Preparation of the CuO•Fe3O4/Silica Composite from Rice Husk for Enhancing Fenton-Like Catalytic Degradation of Tartrazine in a Wide pH Range
Authors: Ngoc Khanh Huyen Pham , Vu Anh-Tuan
Published: June 2022

SiO2 was prepared from rice husk (RH) with the assistance of cetrimonium bromide (CTAB), and the CuO•Fe3O4/SiO2 composite was prepared by a simple coprecipitation method to enhance the Fenton-like degradation of dyes in a wide pH range. SiO2 was a mesoporous material with a relatively large surface area of 496.4 m2/g and a highly relative pore volume of 1.154 cm3/g. The Fe3O4 and CuO particles with the size of 20–50 nm were well dispersed in the composite, making the composite tighter and causing the disappearance of large pores in the range of 20–55 nm. The surface area and pore volume of the composite were reduced to 248.6 m2/g and 0.420 cm3/g, respectively. Fe3O4/SiO2 and Fe3O4 samples only exhibited high catalytic activity in an acidic medium, while the CuO•Fe3O4/SiO2 composite could effectively work in a wide pH range of 3–7. Besides, the effects of reaction conditions such as catalyst dosage, H2O2 concentration, and initial dye concentration on the catalytic performance of the composite were studied. The optimal conditions for the degradation of dye were tartrazine (TA) concentration of 50 mg/L, dosage catalyst of 0.5 g/L, H2O2 concentration of 120 mM, and pH 5. The CuO•Fe3O4/SiO2 composite reached the highest activity at pH 5, showing a degradation efficiency (DE) of 93.3% and a reaction rate of 0.061 min−1. The reusability of the catalyst was investigated by cyclic experiments. The DE of the 3rd reuse remained at 55.1%, equivalent to 93.5% of the first use. The catalytic mechanism for the Fenton system has also been proposed.
Investigation of Coal Preparation for Life Cycle by Using Building Information Modeling (BIM): A Case Study
Authors: Chen Jian , Guo Da-Lin , Dong Xiao-Long , Hou Xiao-Bo , Wang Zhi-Feng
Published: June 2022

Increasing the efficiency of coal preparation is the key link of mine production. This study proposed a framework of coal preparation for life cycle based on Building Information Modeling (BIM), in which the data resources can be retransmitted, and the integration of BIM application links has a high level. In this paper, the kappa big data processing architecture is used to realize the integration and unification of stream data and batch data processing process. By using deep learning method and multimodal data fusion method, the multimodal data association fusion is realized, and Bentley software is adopted for verification and integration. Taking a coal preparation plant as an engineering case study, the proposed framework is applied to build a big data subplatform of three-dimensional visual management. The following is suggested: (1) the three-dimensional visual review of the coal preparation online is realized, and the efficiency of the design results is improved; (2) the production and operation management of the coal preparation are carried out through the established platform, which indicated that the proportion of clean coal increased by 1.97%, and the average increase percentage for the total output is about 5.6%. Results from the case study show that the framework proposed in this study can provide efficient reference for coal washing in the coal preparation.
A Comparative Study of Pejoration in English and Egyptian Vernacular Arabic from a Historical-Sociolinguistic Approach
Authors: Ismail Sayed M. , Lafi Alsulami Lafai bin , Heydarnejad Tahereh
Published: June 2022

Pejoration is an under-researched topic in the Arabic language. This study intends to examine pejoration in Egyptian Arabic, as well as its domains and causes. The study employs a socio-semantic approach for pursuing in-depth investigations of pejoration in Egyptian Arabic. Pejoration was contextually traced with the purpose of revealing how contextual realities, including historical, social, cultural, and even ethical norms, could contribute to the pejorative meaning of given linguistic expressions. The present used a mixed methodology combining qualitative and quantitative approaches. It has been discovered that pejoration in Egyptian Arabic has fallen into several domains such as morphological, prosodic, lexical, metaphorical, and pragmatic through conversational implicature and through slurs. The metaphorical extension of meaning has largely influenced the pejoration process in Egyptian Arabic, and it was found to be high in lexical items charged with sexual connotations. Nouns are more prone to pejoration than adjectives and verbs. Pejoration is largely represented in the vernacular discourse, which contributes to the notable gap between Modern Standard Arabic and Egyptian colloquialism.
The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation
Authors: Yang Bin , Shi Dike , Chen Yahong , Zhu Yi
Published: June 2022

Background. Inflammation within areas of interstitial fibrosis and tubular atrophy (IF/TA) is associated with kidney allograft failure. The aim of this study was to reveal new diagnostic markers of IF/TA based on bioinformatics analysis. Methods. Raw data of IF/TA samples after kidney transplantation and control samples after kidney transplantation were extracted from the Gene Expression Omnibus (GEO) database (GSE76882 and GSE120495 datasets), and genes that were differentially expressed between the two groups (DEGs) were screened. Gene Set Enrichment Analysis (GSEA), ESTIMATE and single sample GSEA (ssGSEA), least absolute shrinkage and selection operator (LASSO) regression analysis, and competing endogenous RNA (ceRNA) network were used to analyze the data. Results. The results of GSEA revealed that multiple immune-related pathways were enriched in the IF/TA group, and subsequent immune landscape analysis also showed that the IF/TA group had higher immune and stromal scores and up to 15 types of immune cells occupied them, such as B cells, cytotoxic cells, and T cells. LASSO regression analysis selected 6 (including ANGPTL3, APOH, LTF, FCGR2B, HLA-DQA2, and EGF) out of 14 DE-IRGs as diagnostic genes to construct a diagnostic model. Then, receiver operating characteristic (ROC) curve analysis showed the powerful diagnostic value of the model, and the area under the curve (AUC) of a single diagnostic gene was greater than 0.75. The results of ingenuity pathway analysis (IPA) also indicated that DEGs were involved in the immune system and kidney disease-related pathways. Finally, we found multiple miRNAs that could regulate diagnostic genes from the ceRNA network. Conclusion. This study identified 6 IF/TA-related genes, which might be used as a new diagnosis model in the clinical practice.
Clinicopathological Significance of AKT1 and PLK1 Expression in Oral Squamous Cell Carcinoma
Authors: Sun Er-Can , Dong Shuang-Shuang , Li Zhi-Jun , Li Chang-Xue
Published: June 2022

Purpose. Oral squamous cell carcinoma (OSCC) is the sixth leading cause of cancer-related death worldwide and is characterized by metastasis and recurrence. We aimed to evaluate the expression of AKT1 and PLK1 in OSCC and identify their correlation with the clinical and histological features and prognosis of patients with OSCC. Methods. Tissue samples were collected from 70 patients with OSCC and 50 patients with normal oral mucosa. The expression levels of AKT1 and PLK1 in OSCC tissues and normal oral mucosa were detected by immunohistochemistry. The chi-square test was used to identify correlations between the expression levels of AKT1 and PLK1 with patients’ clinicopathologic characteristics. Survival analysis was assessed by the Kaplan–Meier method. Spearman’s rank correlation test was used to determine the relationships between AKT1 and PLK1 expressions. The bioinformatics database GEPIA was used to verify the experimental results. Results. The chi-square test and Fisher’s exact test showed that the positive expression rate of AKT1 and PLK1 in OSCC tissue was significantly higher than that in the normal oral mucosa (

P
<
0.05

). PLK1 expression levels were significantly correlated with tumor stage and size (

P
<
0.05

). Kaplan–Meier analysis showed that the survival time of AKT1 and PLK1 with high expression was significantly shorter than that of patients with low expression (

P
<
0.05

). Spearman’s rank correlation test showed a strong correlation between AKT1 and PLK1 expression in OSCC tissue (

R
=
0.53

;

P
<
0.05

). GEPIA bioinformatics database analysis results show that the expression and overall survival of AKT1 and PLK1 analysis and the correlation analysis of AKT1 and PLK1 were consistent with experimental results. Conclusion. AKT1 and PLK1 expressions are associated with the occurrence and progression of OSCC and may be used as diagnostic and prognostic indicators of OSCC. There may be a correlation between AKT1 and PLK1 in OSCC tissue.
A Systematic Mapping Study of Coffee Quality throughout the Production-to-Consumer Chain
Authors: Rendón-Mera Alicia María , Corrales David Camilo , Peñuela Mesa Gustavo Antonio
Published: June 2022

Coffee is one of the most consumed beverages in the world and is crucial in the economy of many developing countries. The search to improve coffee quality comes from many fronts, as do the many ways to measure quality and the factors that affect it. Several techniques are used to measure the different metrics to assess coffee quality, across different types of coffee samples and species, and throughout the entire process from farm to cup. In this work, we conducted a systematic mapping study of 1,470 articles to identify the aspects of quality that are the most important in the scientific literature to evaluate coffee throughout the processing chain. The study revealed that cup quality and biochemical composition are the most researched quality attributes. The main objective of the reviewed studies is the correlation between different quality measurements. The most used techniques are the analytical chemistry methods. The most studied species is Coffea arabica. The most used sample presentation is green coffee. The postharvest stage is the most researched, in which quality control receives more attention. In the preharvest stage, management practices stand out. Finally, the most used type of research was the evaluation research.
Chaotic Phenomena and Oscillations in Dynamical Behaviour of Financial System via Fractional Calculus
Authors: Shah Zahir , Bonyah Ebenezer , Alzahrani Ebraheem , Jan Rashid , Aedh Alreshidi Nasser
Published: June 2022

In this research work, we formulate the phenomena of the financial system in the fractional framework to describe the complex nature of finance. The basic definitions and ideas of the Caputo‐Fabrizio fractional operator are listed. We introduce a novel numerical technique for the dynamical behaviour of our fractional model. The oscillatory and chaotic behaviour of the model is studied with the variation of various input parameters on the model. We have shown that there exists strong oscillatory and chaotic behaviour in the system; moreover, we highlighted the impact of fractional‐order parameter on the model. The conditions for the local complex behaviour of the system are analyzed with the impact of certain parameters on the macroeconomic. Our findings suggest that the values of initial conditions, fractional order, and input parameters can lessen the chaos of the proposed financial system.