bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical case of Gradenigo syndrome, difficulties of differential diagnosis
Authors:   Burdenko Voronezh State Medical University, Ananyeva Elena S. , Popova Marina V. ,   Voronezh Regional Clinical Hospital No. 1, Laricheva Olga B. ,   Voronezh Regional Clinical Hospital No. 1
Published: June 2024

Gradenigo syndrome develops with pathology of the apex of the temporal bone pyramid. This syndrome is characterized by a clinical lesion of the vestibulocochlear nerve in combination with dysfunction of the abducens, trigeminal and facial nerves. The rarity of occurrence of the syndrome, the lack of experience of doctors working with patient with this pathology, the small namber of publications in Russian scientific journals on the diagnosis and treatment of diseases in the area of the apex of the temporal bone lead to the lack of timely diagnosis and adequate treatment of diseases that cause syndrome. The article describes a clinical case of a patient with Gradenigo syndrome, which developed as a result of pathology of the apex of the temporal bone and associated with a neoplasm, which was subsequently determined to be a poorly differentiated carcinoma with squamous cell differentiation of the skull base.
Vulvitis and urinary tract infection in girls
Authors:   Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia, Chekeneva Natalia A. ,   Kulakov National Medical Research Center for oObstetrics, Gynecology and Perinatology
Published: June 2024

Vulvitis is one of the most common disorders with which people come to visit obstetrician-gynecologist. nonspecific bacterial, atopic, infectious vulvitis and vulvitis associated with helminthiasis are most often found in girls under the age of 3 years. Hyperemic mucous membrane of the external genitalia, pain, burning, itching while urinating and at rest are specific clinical features of the disorder; abnormal genital discharge of various types can be also found. Vulvitis often comes along with perineal and perianal dermatitis. Labial fusion and urinary tract infections are common complications of nonspecific inflammation. obstetricians-gynecologists are recommended to conduct diagnosis, treatment, rehabilitation and further follow-up of such girls in cooperation with other related experts, involve pediatric urologist, gastroenterologist, pediatrician; if necessary – dermatovenerologist, enT physician, dentist, infectious disease specialist.
Palliative care in locally advanced breast cancer. Clinical case
Authors:   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Kiseleva Marina V. , Denisov Maksim S. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Litvyakova Elena V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ivanov S.A. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Kaprin A.D. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center,   National Medical Research Radiological Center,   Herzen Moscow Research Oncological Institute – branch of the National, Lun'kova Mariya N. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center
Published: June 2024

Despite introduction of new screening programs and emergence of novel anticancer drugs, the detection rate of advanced breast cancer in Russia is still high, and treatment of such patients requires tailored and sometimes unconventional approach.
Fertility preservation in patients with breast cancer. Literature review
Authors:   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Kiseleva Marina V. , Denisov Maksim S. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Litviakova Elena V. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ivanov S.A. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center,   Patrice Lumumba People’s Friendship University of Russia, Kaprin A.D. ,   National Medical Research Radiological Center, Obninsk, Russia; Patrice Lumumba People’s Friendship University of Russia,   erzen Moscow Research Oncological Institute – branch of the National Medical Research Radiological Center, Lunkova Mariia N. ,   Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center
Published: June 2024

Oncofertility is a discipline that studies the possibility of preserving reproductive function in women with malignant tumors. This new medical discipline is based on two main principles of safety and efficacy. Breast cancer ranks first in the structure of cancer incidence among women of child-bearing age. The paper describes the methods to preserve fertility in breast cancer and their efficacy
ervical intraepithelial neoplasia. Clinical analysis
Authors:   Omsk State Medical University, Klinyshkova Tatiana V. , Frolova Natalia B. ,   Clinical Hospital «Russian Railways-Medicine»
Published: June 2024

Cervical intraepithelial neoplasia (CIN) is the most relevant topic in cervicology due to the risk of progression to cervical cancer and its rejuvenation. The relationship of precancer with human papillomavirus (HPV) expands the range of examination in CIN. Modern approaches to the diagnosis and management of patients with CIN, including the possibilities of immunomorphology, are considered. A clinical examples of the management of a patients with HPV-associated CIN is given.
Comorbidity in gynecology: focus on premenstrual syndrome and irritable bowel syndrome
Authors:   Omsk State Medical University, Trukhan Dmitry I. , Goloshubina Victoria V. ,   Omsk State Medical University, Belkina Larissa V. ,   Omsk Regional Center for the Advanced Training of Health Care Workers
Published: June 2024

According to various sources, from 50 to 80% of women of reproductive age note certain premenstrual symptoms. According to the results of a recent epidemiological study, the prevalence of premenstrual syndrome (PMS) in the Russian Federation is 95%. The prevalence of irritable bowel syndrome (IBS) is 15–20%, while 2/3 of people experiencing IBS symptoms do not go to the doctor ("iceberg phenomenon"). As part of clinical practice, we noted that quite often in patients with functional gastrointestinal disorders, primarily with IBS, a certain worsening of clinical symp-toms coincided in time with the luteal phase of the menstrual cycle. We reviewed the literature in information databases regarding the possible relationship between functional gastrointestinal disorders and PMS. The similarity of the etiology and pathogenesis of IBS and PMS was noted. The presence of a possible comorbidity of IBS and PMS is evidenced by the results of a number of studies and reviews devoted to the study of this relationship, which determines the need for cooperation between gynecologists and gastroenterologists/internists in the management of women with PMS and IBS, and also determines the feasibility of additional studies of the relationship between these two disorders.
Reproductive outcomes of women suffering from adenomyosis-associated infertility
Authors:   Patrice Lumumba Peoples' Friendship University of Russia, Orazov Mekan R. , Mikhaleva Lyudmila M. ,   Avtsyn Research Institute of Human Morphology of Petrovsky National Research Centre of Surgery, Khamoshina Marina B. ,   Patrice Lumumba Peoples' Friendship University of Russia, Barinova Ebecha K. ,   Patrice Lumumba Peoples' Friendship University of Russia
Published: June 2024

Relevance. The identification of the relationship between adenomyosis and infertility, as well as the possible overcoming of the consequences, is one of the main tasks of reproduction. Despite the fact that adenomyosis is more often detected in women of late reproductive age, issues related to its effect on the frequency of pregnancy have not yet been studied. It is also worth noting that the average age of pregnancy among women in developed countries tends to late reproductive age, which is of greater interest for solving the problems of adenomyosis-associated infertility. In this article we present an analysis of the literature data on the effect of adenomyosis on fertility. Objective. Based on the analysis of scientific publications, to consider adenomyosis as a cause of infertility from a contraversion position and to describe the reproductive outcomes in this cohort of patients. Results. A search of literature, publications from Pubmed, Embase and Cochran databases for the last 5 years has been carried out. Molecular studies have provided a deep understanding of the pathogenesis of adenomyosis over the past few years, but there is a huge discrepancy between in vitro research and practice. Radical treatment: endometrial ablation and hysterectomy, used to relieve pain caused by adenomyosis, exclude pregnancy planning. Conclusion. Adenomyosis is a common gynecological disease with an unclear etiology that leads to impaired fertility. The presence of different approaches to the treatment of adenomyosis did not contribute to an increase in the effectiveness in achieving fertility. Since there is still the main problem – time. For example, how long should pregnancy be postponed after treatment and whether hormonal treatment improves the outcome of fertility after surgery, such questions still remain controversial and debatable. Despite numerous studies of the pathogenesis of fertility decline in adenomyosis, their results do not correlate with treatment. We also concluded that adenomyosis has an adverse effect on the clinical results of in vitro fertilization. This reduces the frequency of pregnancy and live birth and increases the frequency of miscarriages. Thus, it is very important to study new, more effective, safer and less invasive strategies for managing women with infertility due to adenomyosis.
Original article Experience in the use of genetically engineered biological drugs for severe bronchial asthma in the Republic of Sakha (Yakutia)
Authors:   Ammosov North-Eastern Federal University, Danilov Aleksey V. , Argunova Agrafena N. ,   Ammosov North-Eastern Federal University, Solovyeva Yulia A. ,   Ammosov North-Eastern Federal University
Published: June 2024

In the Republic of Sakha (Yakutia), from 2001 to 2020, the incidence of asthma is increasing from 4.1 per 1000 population to 12.5 per 1000 population. Considering that currently one of the most effective modern methods of treating severe asthma is genetic engineering biological therapy, research on biologically active medications, as well as the lack of research on this problem in the Yakut population, our work seems relevant. The purpose of this study was to evaluate the effectiveness of treatment with genetic engineering biological drugs (GEBD) in patients with severe asthma in the Yakut population. The study included 17 patients suffering from severe asthma. In 5 patients with severe asthma, the effectiveness of the following GEBD was assessed: anti IL-4, IL-13 drug, in 6 patients – anti IL-5 drug, in 6 patients – anti IgE drug. The effectiveness of treatment was assessed using the ACQ-5 symptom control test, the number of exacerbations over the previous 12 months of asthma therapy, IgE levels, the absolute number of eosinophils, indicators of external respiratory function, and the need of patients for additional asthma therapy. Before initiation, 8 (47.10%) patients had exacerbations and sought medical help; 2 patients were hospitalized in the pulmonology department; after 6 and 12 months, no exacerbations or hospitalizations in specialized hospitals were registered. When using a GEBD for 12 months, the need for inhaled corticosteroids decreased in micrograms/day. Thus, treatment of severe asthma in the Yakut population with GEBD makes it possible to achieve control over its symptoms, reduce the risk of severe exacerbations and the number of hospitalizations, and prevent side effects from high doses of standard therapy.
Musculoskeletal disorders in office employees: outpatient treatment options
Authors:   International Society “Stress under Control”, Akarachkova Elena S. , Kotova Olga V. ,   International Society “Stress under Control”
Published: June 2024

Musculoskeletal neck, shoulder, upper extremity, low back pain is a disorder that is most common in office employees. Furthermore, neck pain and low back pain are the most prevalent. Neck pain and low back pain are in Top-5 of the disorders contributing to disability, ahead of other disorders, such as diabetes mellitus, chronic lung diseases, coronary artery disease. The paper considers pathogenetic features of musculoskeletal disorders developing in office employees, along with treatment options with emphasis on the neurotropic vitamins and their combinations with NSAIDs.
Clinical case of medical rehabilitation of the patient with dilated cardiomyopathy
Authors:   Center for Regenerative Medicine and Rehabilitation ", Grashchenkova Anastasia N. ,   Berezovaia roshcha", Chepkasova Liliya B. ,   Center for Regenerative Medicine and Rehabilitation "Berezovaia roshcha", Puzin Sergey N. ,   Sechenov First Moscow State Medical University (Sechenov University),   Federal Scientific and Clinical Center for Reanimatology and Rehabilitation, Bogova Olga T. ,   Russian Medical Academy of Continuous Professional Education, Ivanova Lyudmila V. ,   Center for Regenerative Medicine and Rehabilitation "Berezovaia roshcha"
Published: June 2024

The paper provides a clinical case of physical and medical rehabilitation of patient D born in 1963. Principal diagnosis established in 2018 according to ICD-10: I42.0 dilated cardiomyopathy. Laboratory testing revealed DNA of herpes virus 6 (HHV6), positive test for cytomegalovirus (CMV) DNA, 6.0×102 copies/mL, positive test for the Epstein–Barr virus (EBV) DNA, 7.2×103 copies/mL. In April 2018, the patient underwent successful surgery, implantation of the biventricular bypass system supplemented by membrane oxygenation. Physical rehabilitation was performed that yielded positive results.
Tuberculosis masks of lung cancer (differential diagnosis, clinical observations)
Authors:   Gorky Donetsk State Medical University, Korzh Elena V. ,   Republican Clinical Tuberculosis Hospital
Published: June 2024

The article presents the main points of differential diagnosis of tuberculosis and various types of lung cancer (central, bronchioloalveolar, peripheral), presents own clinical cases of oncological pathology look like tuberculosis. The key clinical and radiological features that suggest lung cancer are highlighted, the diagnostic errors are analyzed, and ways to improve the quality of diagnosis are outlined. The necessity of integrated additional examinations in case of the slightest doubt about the specific nature of the disease, the importance of evaluating the results of observation in dynamics is emphasized. It has been shown that a single detection of bacterial excretion is not evidence of active pulmonary tuberculosis in the presence of clinical and radiation signs of oncological pathology.
Clinical case of inhibitor form of hemophilia B in a child
Authors:   Kursk State medical university, Serezhkina Alexandra V. , Khmelevskay Irina G. ,   Kursk State medical university, Razinkova Natalya S. ,   Kursk State medical university, Zhiznevskaya Irina I. ,   Kursk State medical university, Minenkova Tatyana A. ,   Kursk State medical university, Feoktistova Tatyana V. ,   Regional children's clinical Hospital, Ivenkov Maxim P. ,   Kursk State medical university
Published: June 2024

Hemophilia B is a hereditary, X-linked recessive disease caused by a violation of plasma homeostasis, resulting from a deficiency or absence of coagulation factor IX (FIX). The cause is a mutation of the Xq27 gene encoding FIX. A serious complication of this pathology is the inhibitory form, clinically manifested by the presence of IgG allo-antibodies neutralizing exogenous FIX. The article describes a clinical case of an inhibitory form of hemophilia B in a 12-year-old child.
Back pain. Results of a non-interventional study of using Ambenium® parenteral in routine clinical practice
Authors:   Central Clinical Hospital with polyclinic of the Office of the President of the Russian Federation, Moscow, Russia, Kurilchenko Dmitry S. ,   Medical Research Center ",   KoMed",   (LLC ",   LR",   ), Kazakova Maya A. ,   City Polyclinic No 23, Branch No 1, Moscow, Russia; Diagnostics LLC, Kupryashkina Yulia G. ,   Diagnostic Center No 3, Branch No 2 (City Polyclinic No 133), Feoktistova Maria V. ,   Demikhov City Clinical Hospital, Kryzhanovskiy Sergey M. ,   Medical Research Center "KoMed" (LLC "LR"), Moscow, Russia; Central State Medical Academy of the Office of the President of the Russian Federation, Chukanova Elena I. ,   Pirogov Russian National Research Medical University
Published: June 2024

Aim: to estimate efficacy, tolerability, and safety of Ambenium® parenteral [phenylbutazone sodium 400 mg and lidocaine hydrochloride 4 mg] used for treatment of patients with low back pain. Methods. A total of 100 patients with low back pain (LBP), who received a single intramuscular injection of Ambenium® parenteral, were included in the study. The follow-up period was 3 days. The change in pain severity on VAS (mm) was selected as a primary outcome measure for efficacy. The pain syndrome severity was estimated before administration of the drug (visit 1) and 4, 6, 8 and 12 h after the drug administration, as well as during visits 2 (day 2) and 3 (day 4). The McGill Pain Questionnaire, muscle syndrome index (MSI), Roland-Morris Disability Questionnaire pain estimates were used as the secondary diagnostic criteria. The percentage of patients with the positive response relative to baseline (the decrease in pain severity on VAS by more than 50%) was also determined. Results. The dynamics of the primary efficacy measure (pain severity on VAS) was as follows: 7.4 ± 0.92 cm (mean ± standard deviation) during visit 1, 5.6 ± 1.49 cm after 2 h, 4.6 ± 1.74 cm after 4 h, 3.0 ± 1.79 cm after 8 h; the VAS score was 2.3 ± 1.70 cm after 12 h (р<0.001). The share of patients who responded to therapy (with the decrease in pain severity on VAS by more than 50% relative to baseline) was 84% [95% CI: 75.0 – 91.0] 24 h after the first administration, 94% during visit 3 [95% CI: 87.0 – 98.0], р<0.001. The secondary efficacy criteria (muscle syndrome index and McGill Pain Questionnaire score) showed significant positive dynamics (р<0.001). No systemic adverse events were reported. Conclusion. The study showed that a single intramuscular injection of Ambenium® parenteral was an efficient, well-tolerated and safe treatment option for low back pain. Administration of a single drug dose makes it possible to ensure a significant clinical effect reflected in the pain severity decrease and restoration of the patient’s motor activity.
Expansão urbana e o fornecimento de serviços ecossistêmicos em Nova Serrana, Minas Gerais, Brasil
Authors: Charles Fonseca  , Sónia Carvalho-Ribeiro  , Carlos Lobo  , Rodrigo Leitão
Published: June 2024

Os serviços ecossistêmicos têm se tornado cada vez mais importantes nos últimos anos, principalmente em resposta às recorrentes mudanças no uso do solo, onde os fragmentos de vegetação nativa inseridos na paisagem desempenham um papel crucial na provisão de tais serviços. Este artigo tem como objetivo identificar e analisar os impactos da expansão urbana no município de Nova Serrana, MG, Brasil, sobre a provisão de serviços ecossistêmicos locais. Foram utilizadas métricas da paisagem para quantificar as mudanças na composição espacial e compreender os resultados dos processos ocorridos ao longo de um período de 15 anos. Nossos resultados mostram que houve uma perda de 781 hectares de manchas de vegetação natural (incluindo florestas e cerrado), principalmente devido à expansão das áreas urbanas. Além disso, as campanhas de campo revelaram outros problemas ambientais, não aparentes nas imagens de satélite, como inundações locais, perda de nascentes e poluição do ar por fábricas de calçado, todos eles consequências da degradação dos serviços ecossistêmicos.
Experiências internacionais de transferência de água entre bacias hidrográficas: reflexões sobre benefícios e desvantagens
Authors: Silva Filho José Antônio da , Leite Francisco Fernando Pinheiro , Alves Larissa da Silva Ferreira , Silva Jairo Bezerra
Published: June 2024

A problemática da oferta desigual de água doce no mundo, atrelada ao crescimento populacional e demandas industriais, agravar-se-á com a ocorrência de fenômenos climáticos extremos como as secas. Há séculos, diversos países utilizam da transferência de água entre bacias hidrográficas superavitárias e deficitárias como forma de superar a escassez hídrica e garantir o desenvolvimento socioeconômico. O presente estudo, uma pesquisa básica exploratória, descritiva e interpretativa, objetiva discutir experiências internacionais de transferências de água interbacias, refletindo sobre seus benefícios e desvantagens. Para isso, realizou-se uma pesquisa bibliográfica com artigos científicos publicados em periódicos nacionais e internacionais que versam sobre transposições interbacias em países como Espanha, China e Estados Unidos da América. Conclui-se que projetos desta magnitude causam impactos das mais diversas matizes, tanto para as áreas doadoras quanto para receptoras, a exemplo de impactos geomorfológicos, invasão biológica, restauração de qualidade de água, e maior disponibilidade hídrica para atividades econômicas.
Território e digitalização: a ação do iFood em Campos dos Goytacazes, Rio de Janeiro, Brasil
Authors: ´Souza Nágila da Silva Ferreira , Silvana Cristina da Silva
Published: June 2024

As plataformas digitais se valem das tecnologias e da racionalidade neoliberal para ampliar suas ações. Trata-se da agudização do meio técnico-científico-informacional. Assim, questionamos: Como a plataformização renova o tecido urbano das cidades? Nosso objetivo é demonstrar como ocorreu a expansão do iFood, tendo o recorte analítico da situação geográfica de Campos dos Goytacazes (2020-2022). A metodologia aplicada incluiu: levantamento bibliográfico; coleta de dados no site e aplicativo do iFood e das corporações associadas a ele; análise do conteúdo do Instagram da empresa; entrevistas com entregadores e estabelecimentos cadastrados; além da sistematização e análise dos dados. Destacamos como resultado que o iFood em Campos dos Goytacazes reforça as desigualdades entre o centro e a periferia. Outrossim, essa plataforma intensifica os fluxos de informações para ampliar sua ação nos lugares e reafirma as centralidades da rede urbana no Brasil. Além disso, destacamos que as plataformas digitais se tornam corporações extratoras de renda dos lugares em escala global.
Tempo de deslocamento como barreira à acessibilidade urbana na Região Metropolitana de São Paulo (RMSP), Brasil
Authors: Silva Ricardo Barbosa da
Published: June 2024

Este artigo tem como objetivo analisar o papel do tempo de deslocamento no transporte coletivo para a acessibilidade urbana aos empregos na Região Metropolitana de São Paulo (RMSP), ao longo das últimas três décadas. A metodologia utilizada combina abordagens quantitativa e qualitativa. A abordagem quantitativa baseou-se na utilização dos microdados da pesquisa Origem e Destino (OD) do Metrô de São Paulo, dos anos de 1997, 2007 e 2017, para analisar a acessibilidade cumulativa aos empregos, em função do tempo de deslocamento por modo coletivo na RMSP. Para a abordagem qualitativa, foram realizadas oficinas de mapeamento colaborativo sobre a acessibilidade com participantes da Universidade dos Centros Educacionais Unificados (UniCEU)/Sistema Universidade Aberta do Brasil (UAB) dos polos Perus, Capão Redondo e Água Azul – Cidade Tiradentes. Constatou-se, então, que o tempo de deslocamento age como barreira à acessibilidade urbana aos empregos, especialmente, aos moradores pobres das periferias urbanas da RMSP.
Financeirização do meio ambiente: respostas apresentadas na COP-26 para desacelerar mudanças climáticas
Authors: Fernandes Carolina
Published: June 2024

O presente artigo discute a financeirização do meio ambiente, que surgiu em paralelo ao Estado neoliberal. Os estados, ainda que atores centrais, têm perdido cada vez mais protagonismo na formulação e na condução das políticas públicas de proteção ambiental, que buscam mitigar os efeitos das mudanças climáticas. Na primeira parte do artigo, é apresentado o debate teórico acerca da financeirização da natureza. Na segunda parte, analisa-se como essa tendência se materializa. Para tanto, são apresentados os resultados da última Conferência das Partes (COP-26), realizada em Glasgow, no Reino Unido, em novembro de 2021, destacando o Pacto Climático de Glasgow, a Declaração dos Líderes de Glasgow sobre Florestas e o Uso do Solo e Coalizão LEAF.
Impactos socioambientais na Baía de Sepetiba, Rio de Janeiro, Brasil: desenvolvimento e restrição do território dos pescadores artesanais
Authors: Corrêa Euzebio Rodrigo
Published: June 2024

O desenvolvimento econômico em curso na borda oeste da metrópole fluminense gera impactos socioambientais para o trabalho da pesca artesanal. No entorno da Baía de Sepetiba, vem-se formando nas últimas décadas um eixo logístico-portuário, com empreendimentos que favorecem a produção e circulação de mercadorias para o mercado internacional. O funcionamento desses empreendimentos altera a materialidade do território, impactando diretamente na atividade da pesca artesanal. O presente artigo objetiva contribuir com o debate ambiental problematizando a racionalidade ambiental que vem se consolidando com o desenvolvimento sustentável. Como resultado, foi observado que os impactos socioambientais provocados pelo desenvolvimento alteraram as condições de territorialidade dos pescadores artesanais, provocando mudanças nas técnicas de pesca e nas relações sociais de trabalho. Esses trabalhadores estão enfrentando cada vez mais restrições no uso do território, resultando na perda dos recursos dos quais eles historicamente dependem há várias gerações.
Geografia econômica, neoliberalismo e ecologia política do desenvolvimento
Authors: De Oliveira Leandro Dias , John Dairo Zapata Ochoa  , Mariana Traldi  , Victor Tinoco Souza
Published: June 2024

Geografia econômica, neoliberalismo e ecologia política do desenvolvimento
ÖRGÜTSEL DEDİKODU DÜZEYLERİNE İLİŞKİN ÖĞRETMEN GÖRÜŞLERİ
Authors: Sari Gülcan , Aslan Hüseyin
Published: June 2024

Bu araştırmanın amacı, öğretmenlerin örgütsel dedikodu düzeylerine ilişkin görüşlerini tespit etmektir. Araştırma nitel araştırma yöntemlerinden olgubilimi deseninde yürütülmüştür. Araştırmanın çalışma grubunu 2023-2024 eğitim öğretim yılında Ordu ili Altınordu ilçesinde görev yapan 20 öğretmen oluşturmaktadır. Araştırmanın çalışma grubunun oluşturulmasında amaçlı örneklem tekniği kullanılmıştır. Veriler yarı yapılandırılmış görüşme formu ile toplanmıştır. Verileri analiz etmek için betimsel analiz tekniğinden yararlanılmıştır. Araştırmada, örgütsel dedikodunun gerçek veya gerçek dışı yorum yapma ve kişinin arkasından konuşma olduğu aynı zamanda olumlu ve olumsuz bir eleştiri ve hızlı yayılan bir iletişim şekli olduğuna ilişkin bulgulara ulaşılmıştır. Ayrıca öğretmenlerin okulda dedikoduya maruz kaldıklarında genellikle yüzleşme, açıklama yapma, ciddiye almama, görmezden gelme ve iletişimi kesme gibi tepkiler gösterdiği anlaşılmıştır. Okulda yapılan dedikodunun nedenleri arasında idareci tutumları, çalışanlar arası iletişimsizlik, kıskançlık, merak, bilgi eksikliği, gruplaşma ve can sıkıntısının etkili olduğu ifade edilmiştir Dedikodunun çalışanlar arası ilişkilerin bozulması, verim ve motivasyon düşüklüğü, psikolojik baskı, iletişim sorunları, kendini değersiz hissetme, stres, mesleki yetersizlik, dışlanmışlık gibi olumsuz sonuçları olduğu anlaşılmıştır.
Rare subgroup of T Lymphocytes in Oral and Maxillofacial Cancer Patients
Authors:   Victor Babeș National Institute of Pathology, Bucharest, Romania, Nicolescu Mihnea Ioan , Dinca Octavian Marius ,   Carol Davila University of Medicine and Pharmacy, Ciocan Lucian Toma ,   Carol Davila University of Medicine and Pharmacy
Published: June 2024

Abstract Malignant tumors of head and neck region represent a heterogenous group of pathologies. Immune phenotype of each tumor might represent valuable information for a putative personalized treatment in the future. We decided to revisit very interesting previous data from a study we conducted in 2003 where we encountered a rare population of CD4+CD8+ double-positive T cells in lymph nodes surgically removed in patients with head and neck malignancies. The study included 27 patients (22 males and 5 females) who underwent surgical procedures that associated lymphadenectomy during March-July 2003 in the Maxillo-Facial Surgery Clinic of „Dan Theodorescu” University Dental Hospital in Bucharest. We encountered a high percentage of CD4+CD8+ T lymphocytes in peripheral blood of non-Hodgkin Lymphoma and poorly differentiated carcinoma, as well as in lymph nodes of both Hodgkin and non-Hodgkin lymphomas. We would like to emphasize the importance of immune phenotyping, when possible, to discriminate between tumor subtypes, evidence that establishing a true identity of the cells involved might be useful for future studies and/or personalized therapeutic strategies.
Factores psicosociales y síndrome de Burnout en docentes universitarios de Ciencias de la Salud
Authors: Martin Bogdanovich María Mini , Agüero Corzo Eucaris del Carmen , Dávila Morán Roberto Carlos
Published: June 2024

La labor docente es esencial en la educación y formación de las generaciones futuras. Estos influyen en el desarrollo de los estudiantes y les proporcionan las herramientas necesarias para alcanzar su potencial máximo. No obstante, enfrentan factores psicosociales que pueden afectar tanto su bienestar emocional como la calidad de su enseñanza. El objetivo de este artículo es  Determinar la relación entre los factores psicosociales y el síndrome de Burnout en docentes de Ciencias de la Salud de una universidad privada en Lima, Perú. La metodología responde al enfoque cuantitativo, diseño no experimental de tipo transversal, correlacional. Participaron 132 profesores de la Facultad de Ciencias de la Salud de una universidad privada en Lima, Perú; mediante el muestreo no probabilístico. Se aplicaron: el “Cuestionario de Factores Psicosociales en el Entorno Académico” y el “Cuestionario Revisado de Burnout en Profesores”. En los resultados se reportó un nivel medio en factores psicosociales con 50,00%, sin embargo, en la dimensión carga de trabajo, se registró un nivel alto, con un 51,52%. También se identificó un nivel medio con 43,94% en la variable síndrome de Burnout. Sin embargo, en cansancio emocional, se observó un nivel alto, con un 49,24%. En conclusión, se determinó que existe relación entre los factores psicosociales y el síndrome de Burnout, con rho = 0,328 y p-valor = 0,000 < 0,05. Esto indica que hay una relación directa y de baja magnitud entre estos dos aspectos.
The Effect of Trust in Food Safety, Perception, Product Features and Consumers’ Characteristics on Consumers’ Purchase Decision for Safe Food: A Systematic Literature Review
Authors: Suhaimi Aishah , Othman Akmal Aini , Ghazali Ahmad Faiz , Kaliani Sundram Veera Pandiyan
Published: June 2024

Food safety incidents have generated consumer concerns and impacted their purchasing decisions significantly. However, the precise ways these incidents affect consumers’ choices and consequences for the food industry remain unclear. This study employs the PRISMA methodology to systematically review existing empirical and conceptual studies to address this gap. A comprehensive search of databases like Web of Science and Scopus using relevant keywords yields 42 pertinent articles after a thorough screening process. This review identifies four key variables influencing consumer behaviour regarding safe food. These variables encompass product features, perceptions of food safety, trust in food safety, and consumers’ characteristics. These variables have collectively shaped consumer preferences for safe food and reflect the complex interplay of internal and external factors, including the role of supply chain actors in managing food safety incidents. The study contributes significantly to current knowledge by comprehensively understanding the factors guiding consumers toward safe food choices. It also introduces a foundational conceptual framework that can be further examined and validated in future research. Beyond academia, the research equips industry stakeholders with vital insights into consumer behaviour, enabling them to effectively formulate strategies that promote food safety and sustainability. Consequently, this study marks a crucial step toward enhancing food safety practices and consumer-centric approaches in the food industry, fostering a safer and more sustainable food environment.
The Department of Obstetrics and Gynecology: Pushing through Changing Times
Authors: Espino Jr., MD Jose Mario C. , De Guzman, MD Glaiza S.
Published: June 2024

The establishment of the Department of Obstetrics and Gynecology can be traced back to the foundation of the University of the Philippines College of Medicine, then called the Philippine Medical School. Obstetrics was originally a separate department, whereas Gynecology was part of the Department of Surgery. This article highlights the Department's history, evolution, and fresh beginnings as it responds to the changing needs of the country.
Outcomes of Abdominal Apical Suspension Using Mesh in a Tertiary Training Hospital: A Seven-year Retrospective Review
Authors: Cadiz, MD Mary Rani M. , Aguinaldo, MD Joanne Karen S.
Published: June 2024

Background. Pelvic organ prolapse (POP) is an inconvenience that can affect a woman’s well-being. Reconstructive pelvic floor surgery involves repairing defects in the endopelvic fascia and pelvic floor musculature as close to the physiologic and anatomic norm. The cornerstone of successful prolapse repair is a strong apical support.
Objective. The aim of the study is to determine the outcomes of abdominal sacrocolpopexy (ASC) and abdominal sacrohysteropexy (ASH) in the Philippines.
Methods. The study utilized a descriptive study design to compare the pre-operative and post-operative Pelvic Organ Prolapse Quantification Score (POP-Q Score), presence of mesh complications, and urinary/bowel symptoms in patients operated within 2010-2016 in a Philippine tertiary training hospital. Based on recovered charts and inclusion/ exclusion criteria, this study sampled 34 of 50 patient records. Statistical measures of median and range were used to describe pre-operative and post-operative POP-Q scores in any two follow-ups within 6-, 12-, 18-, and 24-month interval. The objective success rate and incidence of urinary/bowel symptoms were described using frequencies and percentages. Presence of any mesh erosion was noted for each follow-up. McNemar's test was applied to assess the comparative occurrence of each symptom comparing between the pre-operative and first follow-up periods.
Results. ASC had a success rate of 73.7% at six months and 56.3% at 12 months post-surgery. ASH showed an 84.6% success rate at six months and 71.4% at 12 months. Apical support has a 97% success rate without affecting the anterior or posterior compartments. Out of 20 ASC patients, 5 (25%) exhibited anterior compartment descent, whereas two out of 14 ASH patients (14.2%) had the same condition. It is observed that the anterior vaginal wall has the higher tendency to descend after reconstructive surgery, independent of route or technique. In addition, not all patients with surgical prolapse beyond -1 experienced symptomatic vaginal bulges. Overall, a notable decrease in the occurrence of urine symptoms was seen after the surgery. No mesh erosion was seen within the initial two years of followup but there was a single reported instance of abdominal hernia, an uncommon consequence.
Conclusion. This study demonstrated that ASC and ASH have good success rate in apical support; however, descent of the anterior or posterior compartment diminishes the overall success rate in terms of over-all objective POP-Q score. Both resulted to improvement in symptoms with minimal complications.
Rehabilitacja lecznicza realizowana przez Kasę Rolniczego Ubezpieczenia Społecznego w Centrach Rehabilitacji Rolników KRUS
Authors: Sobiś Iwona , Suchocka-Zielińska Marta
Published: June 2024

Rehabilitacja lecznicza realizowana przez Kasę Rolniczego Ubezpieczenia Społecznego (KRUS, Kasa) jest skierowana do osób ubezpieczonych zagrożonych całkowitą niezdolnością do pracy, osób pobierających okresowe świadczenie rentowe, osób uprawnionych do emerytury rolniczej oraz dla dzieci rolników ubezpieczonych w KRUS lub dzieci uprawnionych do renty rodzinnej. Rehabilitacja lecznicza realizowana w sześciu Centrach Rehabilitacji Rolników KRUS ma na celu przywrócenie do pracy w gospodarstwie rolnym, utrzymanie zdolności do pracy, a w przypadku osób uprawnionych do emerytury rolniczej i dzieci rolników – poprawę stanu zdrowia.

Słowa kluczowe: Centra Rehabilitacji Rolników KRUS, Kasa Rolniczego Ubezpieczenia
Społecznego, rehabilitacja lecznicza, system ubezpieczenia społecznego rolników, turnusy
rehabilitacyjne.
The Agricultural Social Insurance Fund during the COVID-19 pandemic
Authors: Walasek Jacek
Published: June 2024

The COVID-19 pandemic compelled numerous individuals, companies and state institutions
to reassess their surroundings and embrace a new reality. The situation also had its impact on the Agricultural Social Insurance Fund (KRUS, Fund), which, in line with its vision, aims
to become an innovative institution based on societal trust.
The main objective of this study is to present the changes within the KRUS and how the
institution adapted to the needs of farmers during the COVID-19 pandemic.
It addresses changes in the organisation’s functioning, improvements in service accessibility for farmers, and the introduction of new COVID-19-related benefits, along with statistical analysis.

Key terms: COVID-19, hospitalisation, benefits, sickness allowance, care allowance.
Tanzimat Dönemi’nde Gazetecilik ve Haber Çevirileri Üzerine Bir İnceleme
Authors: Işık Serap , Köktürk Şaban
Published: June 2024

Osmanlı Devleti’nde modernleşme ve batılılaşma hareketlerinin hız kazandığı dönem olan Tanzimat dönemi ortaya çıkan yeni edebiyat ve yeni metin türleri açısından özel bir yere sahiptir. Siyasal yönden geri kalmanın etkileri her alanda kendini gösterdiği gibi, sosyal hayatta ve sanatta da açıkça görülür. Batıdaki yenilik ve gelişmeler tüm dünya gibi Türk aydınların da dikkatini çekmiş ve bu doğrultuda adımlar atılmaya başlanmıştır. Özellikle Avrupa’ya gönderilen aydınlar, çeviri yoluyla edebiyata başka bir yön vermede öncülük etmişlerdir. Gazetecilik alanında da yenilik hareketleri kendini göstermiş ve gazete dilinde de değişimler olmuştur. Tanzimat gazeteciliği aynı zamanda yeni edebiyatın temellerini de oluşturmuştur. Çeviri yoluyla edebi dizgeye kazandırılan makale, deneme, köşe yazıları gibi yeni türler sayesinde edebiyatta da yazım türleri çeşitlenmiştir. Yabancı dilde yazılan gazeteler ve çeviri haberler ile ortaya çıkan dil çeşitliliği Türkçenin değişimine de yol açmıştır. Bu çalışmada, yeniliklerin gerçekleştiği bu dönemde çevirinin gazetecilik yoluyla bu değişimleri nasıl yansıttığının, kültür aktarımı için nasıl bir araç haline geldiğinin, çeviri haberlerde kullanılan erek dilin genel olarak nasıl olduğu ve erek dili ne yönde değiştirdiğinin, gazetelerde ne tür çeviri haberlere yer verildiğinin, çeviri haberler sayesinde erek yazın dizgesinin nasıl şekillendiği ve çevirinin gazetecilik anlayışını nasıl şekillendirdiğinin ortaya konması amaçlanmıştır. Çalışma için dönemin gazeteleri ve haber içerikleri üzerine ve basın tarihine ilişkin yapılmış çalışmalar incelenmiştir. Bu çalışmalarda geçen çeviri haberler çalışmanın amaçları doğrultusunda incelendiğinde, çeviri sayesinde her alandan seçilen haberler ile batı kültürünün tanıtılmaya çalışıldığı, genel olarak sade bir dil kullanıldığı, edebi dizgeye giren yeni türler ile yeni bir gazetecilik anlayışı oluşmaya başladığı sonuçlarına varılmıştır.
Automatic Speed Braker Controller
Authors: Mr. Lokesh K S  , Meghana Y  , Manasa N S  , Pavithra H  , Keerthi S
Published: June 2024

This project presents the development of an automatic speed brake controller utilizing the Arduino Uno microcontroller. The primary objective is to enhance vehicle safety by automating the braking process based on real-time speed data. The system comprises several key components: speed sensors, the Arduino Uno, and a braking actuator.
Speed sensors are strategically positioned to continuously monitor the vehicle's velocity, transmitting this data to the Arduino Uno. The microcontroller processes the incoming speed data and compares it against predefined speed thresholds. When the vehicle's speed exceeds these thresholds, the Arduino Uno activates the braking actuator to decelerate the vehicle safely and effectively.
The automatic speed brake controller is designed to address common safety issues such as delayed human reaction times and errors in manual braking. By providing a rapid and automated response to speed changes, the system aims to reduce the risk of collisions and enhance overall road safety. Additionally, this project demonstrates the integration of sensor technology with microcontroller-based control systems, showcasing the potential for advanced automation in vehicular safety features
Brain Stroke Detection using Magnetic Resonance Imaging
Authors: Deeraj C  , Dr. T. Subburaj  , Santhosh S V
Published: June 2024

This project customs innovative machine learnings methods to forecast brain strokes to MRI data. Leveraging high- resolution MRI scans, the model seeks to detect subtle changes indicative of stroke risk. By analyzing features like lesion location and intensity variations, it aims to capture the complex factors contributing to stroke occurrence. Additionally, the model aims to classify stroke subtypes, such as ischemic and hemorrhagic strokes, using multi-modal MRI data for personalized treatment strategies. Validation will be performed on diverse patient datasets, assessing sensitivity, specificity, and AUC- ROC. The outcome targets the advancements of a a therapeutically useful instrument for earley stroke prediction, enabling proactive intervention and improved patient outcomes. By integrating MRI and machine learning, this project aims to advance stroke diagnosis and treatment, reducing the burden on healthcare systems globally
Analysis of Surface Grinding Response Parameter for EN31 Alloy Steel using Taguchi Methodology & Artificial Neural Network and Compression with Cylindrical Grinding Performance Parameter
Authors: Vishal Sharma  , Puneet Sharda
Published: June 2024

Surface finish is extremely important in the manufacturing industry, because getting the correct surface quality is critical. Industries use grinding operations to achieve the desired surface polish on products. Grinding techniques include surface grinding, cylindrical grinding, centerless grinding, and creep-feed grinding. Cylindrical grinding is a machining technique used to refine the external surface of a workpiece. This process involves rotating the workpiece on its axis as a grinding wheel meticulously eliminates material, resulting in the ideal form, size, and surface texture. The work material used in these trials is EN31 steel, which is frequently used in the automobile industry to produce shear blades, molding dies, bolts, and cutting tools. Performance metrics including surface roughness and metal removal rate are assessed using three input parameters: wheel speed (V), depth of cut (D), and number of passes (N) throughout different ranges. Artificial Neural Network (ANN) study carried out in MATLAB software and Taguchi Design utilizing MINITAB are used to discover optimal performance parameters. The ANN receives its input data from the Taguchi method. The lowest surface roughness (Ra) of 0.12000 µm and the highest metal removal rate of 0.83406 grm/sec are shown by the results. Notably, the two most important variables in the surface grinding process are wheel speed and number of passes
Image Noise Reduction with Auto-encoders using TensorFlow
Authors: Dr. T Subburaj  , Bhavana. S
Published: June 2024

Image noise reduction is a fundamental task in image processing with applications in an assortment of fields, including medical imaging, satellite imaging and photography. In this project, we propose an innovative method for image denoising utilizing autoencoders, a particular kind of neural network particularly suited for learning efficient representations of data. We implement our solution using TensorFlow, a popular deep learning framework, leveraging its flexibility and performance capabilities.
Autoencoders consist of two encoders and a decoder, where the encoder maps the input data into a latent space with lower dimensions representation, and the decoder restores the initial input from this representation. By training the autoencoder on pairs of noisy and clean images, it learns to capture the underlying structure of the data while filtering out the noise. Furthermore, we explore extensions and enhancements to our basic model, including incorporating adversarial training techniques like GANs, or generative adversarial networks to further enhance denoising performance. We also discuss potential applications and future directions for research in image denoising using autoencoders. In summary, our work presents a comprehensive framework for image noise reduction utilizing autoencoders implemented in TensorFlow, offering promising results and insights for addressing this critical problem in image processing.
Visualization of Stress Patterns for Stepped Rectangular Specimens Using Experimental Photoelasticity Method and Finite Element Analysis
Authors: Om Prakash Sondhiya  , Roopesh Tiwari
Published: June 2024

In the fields of mechanics and materials science, photoelasticity is a reliable experimental method that provides a visual evaluation and analysis of the distribution of stress in materials that are transparent or translucent. This non- destructive testing technique uses the special property of materials known as birefringence or double refraction to visualize stress on a model under load. The process involves building a physical model that mimics real-world structures, applying mechanical stress to the model, and carefully choosing a suitable photoelastic material that exhibits birefringence. The material undergoes birefringence when it is under stress, which causes changes to its optical characteristics. As a consequence, different stress levels are reflected in the pattern, which makes it easier to identify stress concentrations and possible failure areas and offers insights into how materials behave under varied circumstances. In the current study a photoelasticity unit was used to evaluate the stepped rectangular specimen under four different stresses. Next a comparison was made between the experimental analysis results and ANSYS simulation (Finite Element Analysis). Because of its intuitive user interface, the software functions as a virtual laboratory by enabling simulations with user-defined problem parameters that are tailored to the users circumstances.