bluuebunny/crossref_metadata_2025 huggingface dataset:
Digitalization in Energy Production, Distribution, and Consumption: A Systematic Literature Review
Authors: Simion Cezar-Petre , Verdeș Cătălin-Alexandru , Mironescu Alexandra-Andreea , Anghel Florin-Gabriel
Published: February 2023

For this study, we conducted a systematic review of the literature on digitalization in energy production, distribution, and consumption over a sufficiently long period in order to reveal the trends and particularities of this phenomenon at the sectoral level. For the systematic review of the literature, representative articles on the subject indexed in the Web of Science and Scopus databases were selected using the PRISMA 2020 flow diagram. As a result of the systematic review of the literature, a significant number of articles on the subject of digitalization in the energy sector were found—both over the entire period considered and especially in the last five years—indicating the magnitude of the digitalization process in this field. The impacts of digitalization in the energy production, distribution, and consumption sectors materialized in the aspects of health, safety, and environmental improvement; process improvements; and cost reductions. The most important technologies used in the digitalization process include data mining and machine learning, smart grid/smart metering/smart home, Internet of Things, cybersecurity, and automation solutions (e.g., robotics, drones, and distribution automation).
Electric Vehicle Charging Infrastructure and Energy Resources: A Review
Authors: Aduama Prince , Al-Sumaiti Ameena S. , Al-Hosani Khalifa H.
Published: February 2023

Recent motivation to cut greenhouse gas emissions to combat climate change has led to increasing transportation electrification. However, electric vehicle proliferation comes with a number of challenges such as battery capacities and the range anxiety of electric vehicles. In this paper, a review of the main components that affect electric vehicle adoption, which are charging infrastructure and energy resources, is presented. We discuss the categories of electric vehicle charging infrastructure, based on the location-of-charge and the charging technology. In addition, a review of the energy resources required for electric vehicles is also presented. The key features of these batteries are also discussed.
New Horizons for Microgrids: From Rural Electrification to Space Applications
Authors: Micallef Alexander , Guerrero Josep M. , Vasquez Juan C.
Published: February 2023

The microgrid concept has evolved from the humble origins of simple remote electrification applications in rural environments to complex architectures. Microgrids are key enablers to the integration of higher penetrations of renewables in the energy sector (including electricity, heating, cooling, transport and industry). In addition to the local energy sources, energy storage systems and loads, the modern microgrid encompasses sophisticated energy and power management systems, peer-to-peer energy markets and digital technologies to support this energy transition. The microgrid concept has recently been applied to all energy sectors, in order to develop solutions that address pressing issues related to climate change and the decarbonization of these important sectors. This paper initially reviews novel applications in which the microgrid concept is being applied, from a detailed analysis of recent literature. This consists of a comprehensive analysis of the state of the art in shipboard microgrids, port microgrids, aircraft microgrids, airport microgrids and space microgrids. Future research directions are then presented, based on the authors’ perspectives on pushing the boundaries of microgrids further.
The Fractured Permian Reservoir and Its Significance in the Gas Exploitation in the Sichuan Basin, China
Authors: Luo Xin , Chen Siqi , Liu Jiawei , Li Fei , Feng Liang , Li Siyao , Wu Yonghong , Wu Guanghui , Luo Bin
Published: February 2023

Large gas reserves have been found in the Permian platform margin of the Kaijiang-Liangping area of the Sichuan Basin in SW China. They are assumed to be a widely developed reef–shoal reservoir. However, the tight matrix reservoir cannot support high gas production using conventional development technology at deep subsurface. In this contribution, we analyze the fractured reservoirs along the strike-slip fault zones using the compiled data of cores, well logging, and production data, and provide a seismic description. It was shown that the fractures and their dissolution developed along the strike-slip fault zones. The porosity and permeability of the fractured reservoir could increase by more than one and 1–2 orders of magnitude, respectively. The seismic anisotropic energy found in the steerable pyramid process suggests that fractured reservoirs have a strong heterogeneity, with a localized fault damage zone. This fracturing has both positive and negative effects, showing varied reservoir parameters in the fault damage zone. The development pattern should adopt a non-uniform well pattern, in order to target the localized “sweet spot” of the fractures in these deep tight matrix reservoirs.
Pipe Model Can Accurately Estimate Crown Biomass of Larch (Larix olgensis) Plantation Forest in Northeast China
Authors: Huang Chenyu , Zhang Yuanyuan , Chen Lu , Zhuang Liwen , Zhang Yanliang , Sang Weiguo
Published: February 2023

The pipe model theory has been applied to estimate allometry of trees in many regions; however, its reliability and generality need more verification for estimating crown biomass in China. In the present study, the crown biomass of Larix olgensis plantations in four sites in northeast China was estimated using the pipe model, and the correlation efficiency index of larch crown biomass for pipe model estimation was 0.953. The crown biomass of larch plantations could be accurately estimated by the tree height, crown base height, and stem area at breast height. Meanwhile, the effects of site, stand density, and age on the accuracy of crown biomass estimated by the pipe model were detected. The covariance analysis showed that the effect of age on crown biomass was 0.024, indicating that age had a significant effect on the estimation accuracy in this model, while site and stand density had no significant effects (p = 0.180 and p = 0.169). Our study showed that the crown biomass of L. olgensis plantations in northeast China could be accurately estimated using the pipe model, and we recommend considering the age effect in practical applications.
Forest Segmentation with Spatial Pyramid Pooling Modules: A Surveillance System Based on Satellite Images
Authors: Ru Fung Xin , Zulkifley Mohd Asyraf , Abdani Siti Raihanah , Spraggon Martin
Published: February 2023

The global deforestation rate continues to worsen each year, and will eventually lead to various negative consequences for humans and the environment. It is essential to develop an effective forest monitoring system to detect any changes in forest areas, in particular, by monitoring the progress of forest conservation efforts. In general, changes in forest status are difficult to annotate manually, whereby the boundaries can be small in size or hard to discern, especially in areas that are bordering residential areas. The previously implemented forest monitoring systems were ineffective due to their use of low-resolution satellite images and the inefficiency of drone-based data that offer a limited field of view. Most government agencies also still rely on manual annotation, which makes the monitoring process time-consuming, tedious, and expensive. Therefore, the goal of this study is to overcome these issues by developing a forest monitoring system that relies on a robust deep semantic segmentation network that is capable of discerning forest boundaries automatically, so that any changes over the years can be tracked. The backbone of this system is based on satellite imaging supplied to a modified U-Net deep architecture to incorporate multi-scale modules to deliver the semantic segmentation output. A dataset of 6048 Landsat-8 satellite sub-images that were taken from eight land parcels of forest areas was collected and annotated, and then further divided into training and testing datasets. The novelty of this system is the optimal integration of the spatial pyramid pooling (SPP) mechanism into the base model, which allows the model to effectively segment forest areas regardless of their varying sizes, patterns, and colors. To investigate the impact of SPP on the forest segmentation system, a set of experiments was conducted by integrating several variants of SPP ranging from two to four parallel paths with different combinations of pooling kernel size, placed at the bottleneck layer of the U-Net model. The results demonstrated the effectiveness of the SPP module in improving the performance of the forest segmentation system by 2.57%, 6.74%, and 7.75% in accuracy (acc), intersection over union (IoU), and F1-score (F1score), respectively. The best SPP variant consists of four parallel paths with a combination of pooling kernel sizes of 2×2, 4×4, 6×6, and 8×8 pixels that produced the highest acc, IoU, and F1score of 86.71%, 75.59%, and 82.88%, respectively. As a result, the multi-scale module improved the proposed forest segmentation system, making it a highly useful system for government and private agencies in tracking any changes in forest areas.
Diurnal Monitoring of Moisture Content of Scots Pine and Small-Leaved Lime Trunks Using Ground Penetrating Radar (GPR) and Increment Cores
Authors: Sudakova Maria , Terentieva Eugenia , Kalashnikov Alexey , Seregin Ivan , Yaroslavtsev Alexey
Published: February 2023

Ground penetrating radar is non-invasive technology suitable for mapping moisture content variations since it shows high sensitivity to changes in water saturation. In this work we used a GPR tomography approach to estimate moisture content within two small-leaved lime (Tilia cordata) and two Scots pine (Pinus sylvestris) trunks. Additional information was derived using the method of GPR zero-offset. GPR data was collected in Moscow (diurnal monitoring in September 2021) using a shielded GPR antenna working at 1500 MHz. Moisture values derived from GPR data were compared with the values obtained directly by measuring sampled wood cores gravimetrically. A good agreement was observed between GPR-derived moisture content and core sample-derived values. Notwithstanding GPR-derived moisture content is about two times higher than core sample-derived values, a strong linear relation with a determination coefficient more than 0.8 is observed. Diurnal monitoring did not reveal any significant changes in moisture content inside the trunks. It can be concluded that the period of early autumn in the Moscow region is characterized by a constant moisture content of the small-leaved lime trunk during the day.
Canadian Fire Management Agency Readiness for WildFireSat: Assessment and Strategies for Enhanced Preparedness
Authors: McFayden Colin B. , Hope Emily S. , Boychuk Den , Johnston Lynn M. , Richardson Ashlin , Coyle Matthew , Sloane Meghan , Cantin Alan S. , Johnston Joshua M. , Lynham Timothy J.
Published: February 2023

Wildfires are worsening in Canada and globally, partly due to climate change. The government of Canada is designing and building WildFireSat, the world’s first purpose-built operational satellite system for wildfire monitoring. It will provide new fire intelligence to support decision-making. It takes time for fire management agencies to use new information: to understand it and its implications, change processes, develop training, and modify computer systems. Preparing for the system’s prelaunch will allow agencies to benefit more rapidly from the new information. We present (1) an assessment of the readiness of 12 Canadian fire management agencies to integrate WildFireSat information and (2) guidance for reducing readiness gaps. We used survey and other data to score readiness indicators for three readiness components: understanding, organization, and information technology. We weighted the influence of each indicator score on each component. We modelled scoring and weighting uncertainties and used Monte Carlo simulation to generate distributions of aggregated agency readiness. The results indicated that most agencies have a moderate level of readiness while others have a higher level of readiness. Cluster analysis was used to group agencies by similarity in multiple dimensions. Strategies for increasing readiness are highlighted. This identifies opportunities for agencies and the WildFireSat team to collaborate on enhancing readiness for the forthcoming WildFireSat data products.
Characterization of Red Sea Bream (Pagrus major) Interferon Regulatory Factor 5 and 6 Genes and Their Expression in Response to RSIV Infection
Authors: Kim Kyung-Ho , Joo Min-Soo , Kang Gyoungsik , Woo Won-Sik , Sohn Min-Young , Son Ha-Jeong , Park Chan-Il
Published: February 2023

Interferon regulatory factors (IRFs) play crucial roles in antiviral processes, such as in the transcriptional induction of interferon (IFN) and IFN-stimulated genes (ISGs). In this study, the genes encoding IRF5 and IRF6 were identified in Pagrus major, and their expression in various organs after pathogen infection was analyzed. In the coding sequences of P. major (Pm)IRF5 and PmIRF6, the DNA binding domain, IRF association domain, and viral-activated domain were found to be highly conserved. Phylogenetic analysis revealed that PmIRF5 and PmIRF6 were most closely related to IRF5 and IRF6 of large yellow croakers. The mRNAs for PmIRF5 and PmIRF6 were constitutively expressed in all organs analyzed but were highly expressed in the liver and gills. As a result of an infection with red sea bream iridovirus, a major pathogen of red sea bream, PmIRF5 and PmIRF6 expression was significantly upregulated in the spleen and kidney. On the basis of these results, it can be concluded that IRF5 and IRF6 expression play an influential role in the immune system of red sea bream infected with viruses.
Certain Sharp Coefficient Results on a Subclass of Starlike Functions Defined by the Quotient of Analytic Functions
Authors: Shi Lei , Arif Muhammad
Published: February 2023

In the present paper, we consider a subclass of starlike functions G3/2 defined by the ratio of analytic representations of convex and starlike functions. The main aim is to determine the bounds of Fekete–Szegö-type inequalities and Hankel determinants for functions in this class. It is proved that maxH3,1(f):f∈G3/2 is equal to 181. The bounds for f∈G3/2 are sharp.
Land Use and Land Cover Change in the Vaal Dam Catchment, South Africa: A Study Based on Remote Sensing and Time Series Analysis
Authors: Obaid Altayeb , Adam Elhadi , Ali K. Adem
Published: February 2023

Understanding long-term land use/land cover (LULC) change patterns is vital to implementing policies for effective environmental management practices and sustainable land use. This study assessed patterns of change in LULC in the Vaal Dam Catchment area, one of the most critically important areas in South Africa, since it contributes a vast portion of water to the Vaal Dam Reservoir. The reservoir has been used to supply water to about 13 million inhabitants in Gauteng province and its surrounding areas. Multi-temporal Landsat imagery series were used to map LULC changes between 1986 and 2021. The LULC classification was performed by applying the random forest (RF) algorithm to the Landsat data. The change-detection analysis showed grassland being the dominant land cover type (ranging from 52% to 57% of the study area) during the entire period. The second most dominant land cover type was agricultural land, which included cleared fields, while cultivated land covered around 41% of the study area. Other land use types covering small portions of the study area included settlements, mining activities, water bodies and woody vegetation. Time series analysis showed patterns of increasing and decreasing changes for all land cover types, except in the settlement class, which showed continuous increase owing to population growth. From the study results, the settlement class increased considerably for 1986–1993, 1993–2000, 2000–2007, 2007–2014 and 2014–2021 by 712.64 ha (0.02%), 10245.94 ha (0.26%), 3736.62 ha (0.1%), 1872.09 ha (0.05%) and 3801.06 ha (0.1%), respectively. This study highlights the importance of using remote sensing techniques in detecting LULC changes in this vitally important catchment.
Haemophilia A: A Review of Clinical Manifestations, Treatment, Mutations, and the Development of Inhibitors
Authors: Sarmiento Doncel Samuel , Díaz Mosquera Gina Alejandra , Cortes Javier Mauricio , Agudelo Rico Carol , Meza Cadavid Francisco Javier , Peláez Ronald Guillermo
Published: February 2023

The purpose of this narrative review was to provide an overview that allows readers to improve their understanding of hemophilia A, which is considered a genetic disease with a high impact on the quality of life of people who suffer from it is considered one of the diseases with the highest cost for health systems (In Colombia it is part of the five diseases with the greatest economic impact). After this exhaustive review, we can see that the treatment of hemophilia is on the way to precision medicine, which involves genetic variables specific to each race and ethnicity, pharmacokinetics (PK), as well as environmental factors and lifestyle. Knowing the impact of each of these variables and their relationship with the efficacy of treatment (prophylaxis: regular infusion of the missing clotting factor VIII in order to prevent spontaneous bleeding) will allow for individualizing the medical behavior in a cost-effective way. For this is required to build more strong scientific evidence with statistical power that allows us to infer.
A Comprehensive Review on Wastewater Nitrogen Removal and Its Recovery Processes
Authors: Zhou Yifan , Zhu Yingying , Zhu Jinyuan , Li Chaoran , Chen Geng
Published: February 2023

Discharging large amounts of domestic and industrial wastewater drastically increases the reactive nitrogen content in aquatic ecosystems, which causes severe ecological stress and biodiversity loss. This paper reviews three common types of denitrification processes, including physical, chemical, and biological processes, and mainly focuses on the membrane technology for nitrogen recovery. The applicable conditions and effects of various treatment methods, as well as the advantages, disadvantages, and influencing factors of membrane technologies, are summarized. Finally, it is proposed that developing effective combinations of different treatment methods and researching new processes with high efficiency, economy, and energy savings, such as microbial fuel cells and anaerobic osmotic membrane bioreactors, are the research and development directions of wastewater treatment processes.
Research on the Impact of Green Innovation Network Embeddedness on Corporate Environmental Responsibility
Authors: Wang Junli , Lv Wendong
Published: February 2023

In the process of China’s economic transformation, enterprises urgently need to use green innovation networks to realize corporate sustainability. Based on resource-based theory, this study explores the internal mechanism and boundary conditions of green innovation network embeddedness that affect corporate environmental responsibility. This paper conducts an empirical study based on panel data of listed companies engaged in green innovation in China from 2010 to 2020. Drawing on network embeddedness theory and resource-based theory, we found that relational and structural embeddedness influenced green reputation, which affected corporate environmental responsibility. We also identified the importance of ethical leadership and examined its role in moderating the effect of green innovation network embeddedness. A further investigation revealed that the impact of network embeddedness on corporate environmental responsibility was particularly pronounced in the samples of enterprises with high-level political ties, loose financing restrictions, and nonstate ownership. Our findings highlight the advantages of embedded green innovation networks and offer theoretical references and recommendations for enterprises considering network participation. Enterprises should attach great importance to the network embedding strategy of green innovation for corporate environmental responsibility and actively integrate the concept of green development into network relationship embedding and network structure embedding. Moreover, the relevant government department should provide necessary environment incentive policies according to the enterprise’s development needs, especially for the enterprises with low-level political ties, high financing restrictions, and state ownership.
Effectiveness of Group Parent-Child Interaction Therapy on Problem Behaviors in Chinese Kindergartners
Authors: Sun Juanjuan , Liu Mowei , Li Xiaoyun , Zhou Yuena , Li Yan
Published: February 2023

Problem behaviors in early childhood may put young children at risk for negative behavioral and psychosocial problems. This study examined the effectiveness of group PCIT on Chinese young children’s externalizing and internalizing problems. The participants were 58 mothers with their children aged 2–3 years (M = 2.95 years, SD = 0.22), assigned to an immediate treatment (n = 26) group or to a waitlist (n = 32) control group. The program involved comprehensive group intervention and featured weekly 60–90-min sessions, totaling ten sessions over three months. Results indicate that group PCIT not only significantly improved teacher-reported problem behaviors in children, but also improved observed maternal parenting behavior. These findings support the use of group PCIT in Chinese children and provide mothers with an evidence-based tool to address problem behaviors in a non-clinical population.
Routine Ophthalmological Examination Rates in Adults with Sickle Cell Disease Are Low and Must Be Improved
Authors: Zulueta Patricia , Minniti Caterina P. , Rai Anvit , Toribio Tiana J. , Moon Jee-Young , Mian Umar K.
Published: February 2023

The American Academy of Ophthalmology and the National Heart, Lung and Blood Institute recommend patients with sickle cell disease (SCD) undergo dilated funduscopic exams (DFE) every 1–2 years to screen for sickle retinopathy. There is a paucity of data on the adherence rate to these guidelines; a retrospective study was performed to evaluate our institution’s adherence. A chart review of 842 adults with SCD, seen 3/2017–3/2021 in the Montefiore healthcare system (All Patients), was done. Only about half of All Patients (n = 842) had >1 DFE during the study period (Total Examined Patients, n = 415). The Total Examined Patients were categorized as screening, those without retinopathy (Retinopathy−, n = 199), or follow-up, including individuals previously diagnosed with retinopathy (Retinopathy+, n = 216). Only 40.3% of screening patients (n = 87) had DFE at least biennially. As expected, there was a significant decrease in the average DFE rate of the Total Examined Patients after the COVID-19 pandemic started (13.6%) compared to pre-COVID (29.8%, p < 0.001). Similarly, there was a significant decrease in the screening rate of Retinopathy− patients from 18.6% on average pre-COVID to 6.7% during COVID (p < 0.001). This data shows the sickle retinopathy screening rate is low and innovative approaches may need to be employed to remedy this issue.
A Shift in Asthma Treatment According to New Guidelines: An Evaluation of Asthma Patients’ Attitudes towards Treatment Change
Authors: Holst Sara Sommer , Sabedin Ebru , Sabedin Esin , Vermehren Charlotte
Published: February 2023

The Global Initiative for Asthma (GINA) has presented a shift in pharmacological asthma treatment. The objective of this study was to explore factors influencing a successful switch to a new asthma treatment approach with a focus on asthma patients’ attitudes toward treatment change and supportive initiatives. This study was performed as a case study involving a quantitative questionnaire and a qualitative semi-structured interview. A total of 284 responses were collected from the questionnaire, and 141 responses were included. The results showed that asthma patients thought that effectiveness of the new treatment approach, doctor recommendation, and knowledge of the new treatment approach were the most important factors influencing treatment change considerations. Nine interviews were conducted where the main themes were barriers to a shift in asthma treatment, such as effects and side effects of the new treatment, the role of the general practitioner (GP) and conflicts in agreeing on a treatment plan; as well as facilitators to a shift in asthma treatment, such as trust in the GP and easier inhaler use. We found several supportive initiatives, such as consultation with the GP, handing out information leaflets and a consultation at the pharmacy. In conclusion, this study uniquely identified factors that may influence successful treatment shifts in asthma patients that may be instrumental in understanding similar situations in other pharmacological settings.
The Resilience of South African School Teachers in the Time of COVID-19: Coping with Risk of Infection, Loneliness, and Anxiety
Authors: Padmanabhanunni Anita , Pretorius Tyrone
Published: February 2023

The COVID-19 pandemic precipitated an overall increase in the global prevalence of mental health disorders and psychological distress. However, against this backdrop, there was also evidence of adaptation and coping, which suggested the influence of protective factors. The current study aims to extend previous research on the role of protective factors by investigating the health-sustaining and mediating roles of resilience in the relationship between perceived vulnerability to disease, loneliness, and anxiety. Participants consisted of a convenience sample of schoolteachers (N = 355) who completed the Perceived Vulnerability to Disease Questionnaire, the short form of the Connor–Davidson Resilience Scale, the University of California, Los Angeles Loneliness Scale, and the trait scale of the Spielberger State-Trait Anxiety Scale, through an online link created with Google Forms. The results of path analysis indicated significant negative associations between resilience and both loneliness and anxiety. These results indicate the health-sustaining role of resilience. In addition, resilience mediated the relationships between germ aversion and perceived infectability, on the one hand, and loneliness and anxiety, on the other hand. The findings confirm that resilience can play a substantial role in counteracting the negative impact of the pandemic on mental health.
Influence of Selected Sociodemographic and Cultural Factors on the Age of Sexual Initiation of Students from Polish Universities
Authors: Stokłosa Maciej , Stokłosa Iga , Więckiewicz Gniewko , Porwolik Mateusz , Bugajski Maciej , Męcik-Kronenberg Tomasz , Pudlo Robert , Gorczyca Piotr , Piegza Magdalena
Published: February 2023

Sexuality is the one of the most important parts of human life. The aim of our study was to identify the factors influencing the onset and age of sexual initiation in students and drawing attention to the need to improve access to sexual education in Polish schools at a sufficiently high level. An original questionnaire with 31 questions was used for the study. Data were collected using the Google Forms tool. A total of 7528 students participated in the study and 5824 underwent sexual initiation. The mean age at sexual initiation was 18.1 years. Logistic regression analysis was performed to show factors influencing the onset of sexual activity, while linear regression analysis was used for factors influencing the age of sexual initiation. Religion, drug use, smoking, alcohol consumption, type of housing, and conversations with parents about contraception or sex affect the onset of sexual activity. The age of sexual initiation is affected by religion, the age of the first viewing of pornography, quality of life, the size of the city of residence, smoking and drug use.
Multi-Disaster Integrated Risk Assessment in City Range—A Case Study of Jinan, China
Authors: Chang Jun , Yin Zuotang , Zhang Zhendong , Xu Xiaotong , Zhao Min
Published: February 2023

Urban multi-disaster integrated risk assessment is an important part of urban sustainable development and territorial spatial planning. Based on the results of integrated risk assessment, the scientific and effective performance of disaster prevention and reduction can be effectively improved. This study determines a multi-disaster integrated risk assessment system. The system evaluates the hazard level of disasters, the exposure level of disaster bearing bodies, the vulnerability level of disaster bearing bodies, and the urban resilience level, and determines the city’s integrated risk level on this basis. Taking Jinan as an example, the risk, exposure, vulnerability, resilience, and integrated risk level of Jinan City were analyzed. The results show that the system reasonably analyzes the multi-disaster integrated risk level, and according to the assessment results, countermeasures for disaster prevention and suggestions for territorial spatial planning were put forward.
Is (Disordered) Social Networking Sites Usage a Risk Factor for Dysfunctional Eating and Exercise Behavior?
Authors: Mader Lisa , Müller Kai W. , Wölfling Klaus , Beutel Manfred E. , Scherer Lara
Published: February 2023

Background: Research over the past years has shown that exposure to thin and beauty ideals in the media can be associated with disordered eating and related variables. Nowadays, interactive media, such as social networking sites, have gained growing popularity and represent a major part of people’s lives. It is therefore crucial to investigate how far users might be negatively influenced by social networking sites regarding eating pathology or excessive exercise behavior and if there are particular links to social media use disorder. Methods: Data were collected by an online-survey encompassing questions on regular social networking site use, eating disorders, and excessive exercise behavior. Results: Analyses showed that disordered social networking sites use was significantly related to eating pathology and a poorer body image in men and women. The frequency of active or passive social networking sites usage however was not associated with exercise behavior. Conclusions: Our results confirm that disordered social networking sites use represents a risk factor for body image dissatisfaction and associated eating disorders.
Multi-Level Attention Recognition of EEG Based on Feature Selection
Authors: Xu Xin , Nie Xu , Zhang Jiaxin , Xu Tingting
Published: February 2023

In view of the fact that current attention-recognition studies are mostly single-level-based, this paper proposes a multi-level attention-recognition method based on feature selection. Four experimental scenarios are designed to induce high, medium, low, and non-externally directed attention states. A total of 10 features are extracted from 10 electroencephalogram (EEG) channels, respectively, including time-domain measurements, sample entropy, and frequency band energy ratios. Based on all extracted features, an 88.7% recognition accuracy is achieved when classifying the four different attention states using the support vector machine (SVM) classifier. Afterwards, the sequence-forward-selection method is employed to select the optimal feature subset with high discriminating power from the original feature set. Experimental results show that the classification accuracy can be improved to 94.1% using the filtered feature subsets. In addition, the average recognition accuracy based on single subject classification is improved from 90.03% to 92.00%. The promising results indicate the effectiveness of feature selection in improving the performance of multi-level attention-recognition tasks.
Quercetin and Its Derivative Counteract Palmitate-Dependent Lipotoxicity by Inhibiting Oxidative Stress and Inflammation in Cardiomyocytes
Authors: Granieri Maria Concetta , Rocca Carmine , De Bartolo Anna , Nettore Immacolata Cristina , Rago Vittoria , Romeo Naomi , Ceramella Jessica , Mariconda Annaluisa , Macchia Paolo Emidio , Ungaro Paola , Sinicropi Maria Stefania , Angelone Tommaso
Published: February 2023

Cardiac lipotoxicity plays an important role in the pathogenesis of obesity-related cardiovascular disease. The flavonoid quercetin (QUE), a nutraceutical compound that is abundant in the “Mediterranean diet”, has been shown to be a potential therapeutic agent in cardiac and metabolic diseases. Here, we investigated the beneficial role of QUE and its derivative Q2, which demonstrates improved bioavailability and chemical stability, in cardiac lipotoxicity. To this end, H9c2 cardiomyocytes were pre-treated with QUE or Q2 and then exposed to palmitate (PA) to recapitulate the cardiac lipotoxicity occurring in obesity. Our results showed that both QUE and Q2 significantly attenuated PA-dependent cell death, although QUE was effective at a lower concentration (50 nM) when compared with Q2 (250 nM). QUE decreased the release of lactate dehydrogenase (LDH), an important indicator of cytotoxicity, and the accumulation of intracellular lipid droplets triggered by PA. On the other hand, QUE protected cardiomyocytes from PA-induced oxidative stress by counteracting the formation of malondialdehyde (MDA) and protein carbonyl groups (which are indicators of lipid peroxidation and protein oxidation, respectively) and intracellular ROS generation, and by improving the enzymatic activities of catalase and superoxide dismutase (SOD). Pre-treatment with QUE also significantly attenuated the inflammatory response induced by PA by reducing the release of key proinflammatory cytokines (IL-1β and TNF-α). Similar to QUE, Q2 (250 nM) also significantly counteracted the PA-provoked increase in intracellular lipid droplets, LDH, and MDA, improving SOD activity and decreasing the release of IL-1β and TNF-α. These results suggest that QUE and Q2 could be considered potential therapeutics for the treatment of the cardiac lipotoxicity that occurs in obesity and metabolic diseases.
“We Want to See Youth That Would Be Better People Than Us”: A Case Report on Addressing Adolescent Substance Use in Rural South Africa
Authors: David Ifeolu , Wegner Lisa , Majee Wilson
Published: February 2023

Research suggests that substance use, particularly among adolescents may lead to increased illegal activities as well as physical and social health consequences. Around the world, communities, overburdened with adolescent and youth substance use, are finding ways to address this public health threat. Using a case study based on a focus group discussion with nine founding members, this paper reports on the case of Sibanye—a rural community coalition whose mission is to reduce the burden of adolescent substance use on families in rural South Africa. The focus group discussions were audio-recorded, transcribed verbatim, and analyzed using Nvivo 12. This work highlights the power of an engaged collective effort in addressing key community issues, even in rural areas of emerging economies where health and community infrastructure may be limited. The Sibanye coalition taps into its collective wealth of community knowledge to provide social contributions and aesthetics to help adolescents abstain from substance use and sexual risk behaviors. These activities offer adolescents safe places to meet each other, health education, and the ability to structure their free time meaningfully. Engaging community residents, particularly disadvantaged groups, should be central to any local and national strategies for promoting health and well-being.
Dementia and COVID-19 among Older African American Adults: A Scoping Review of Healthcare Access and Resources
Authors: Udoh Idorenyin Imoh , Mpofu Elias , Prybutok Gayle
Published: February 2023

African American/Black communities comprise 12.2% of the U.S. population, with a COVID-19 infection rate of more than 18% and marginal access to healthcare services. This scoping review synthesizes the emerging evidence on healthcare accessibility among older African American adult communities with dementia and COVID-19, as well as the resource requirements for this population during the pandemic. Searches of different databases for empirical studies and other sources on dementia and COVID-19 among older African American adults yielded 13 studies that met the following inclusion criteria: (a) focus on dementia and COVID-19, (b) sampled older African American adults, (c) investigated healthcare accessibility and resources, and (d) published between 2019 and 2022. Following the initial selection of the studies, eight were selected for relevance based on the Population, Concept, and Context (PCC) inclusion and exclusion criteria. Thematic analysis indicated that older African Americans with dementia and COVID-19 experienced longer delays in accessing timely healthcare, including transportation, intensive care units (ICUs), and mechanical ventilation. They also had reduced healthcare resources associated with a lack of health insurance, low financial resources, and an increased length of hospital stay, which further aggravated the negative effects of comorbid dementia and COVID-19 infections. Evidence showed that racial and age disparities affected older African American adults with dementia and COVID-19, resulting in lower healthcare access and marginal resources. This is consistent with historical and systemic inequities in meeting the healthcare needs of people of color in the United States, which was compounded for older African Americans during the COVID-19 pandemic.
Assessment of the Carrying Capacity and Suitability of Spatial Resources and the Environment and Diagnosis of Obstacle Factors in the Yellow River Basin
Authors: Chen Yu , Liu Shuangshuang , Ma Wenbo , Zhou Qian
Published: February 2023

The assessment of the carrying capacity and suitability of spatial resources and the environment can provide effective guidance for regional planning and make vital contributions to the high-quality advancement of society and the economy. Additionally, this scientific evaluation of the spatial carrying capacity and suitability of urban production–living–ecological space (PLES) has important scientific value as well as practical significance for territorial spatial planning. This paper takes the cities along the Yellow River Basin (YRB) as the research object; establishes the PLES resource and environment carrying capacity evaluation index system; uses the multi-indicator superposition method and entropy weight method to evaluate the ecological importance, production and life carrying capacity of 78 cities in the YRB from 2010 to 2020; obtains the final ecological importance, production and life suitability levels based on the carrying capacity combined with the location conditions; and uses exploratory spatial data analysis (ESDA), the barrier degree model and other methods to determine the cities’ spatial and temporal patterns and influencing factors. The findings indicate that: (1) Ecological importance is characterized by “high upstream and low downstream”; the suitability for production is higher mainly in the eastern coastal area; the suitability of life as a whole is increasing, and the higher grade is in some provincial capitals and surrounding cities. (2) The local Moran’s I all passed the test, and the relationship between PLES showed a significant positive spatial correlation. The clustering characteristics of ecological importance and production suitability are strong, while the clustering characteristics of suitability for living functions are relatively weak. (3) Biodiversity, significance of water conservation and significance of wind and grit control functions are the main barrier factors affecting the ecological importance of the YRB; industrial value-added output per unit of industrial land, number of industrial enterprises above the scale and GDP per capita are the dominant factors affecting the production suitability of the study area; total water-resource utilization per capita, total sewage treatment per capita and residential land area per capita are the main barrier factors of living suitability.
The Low-Carbon Policy and Urban Green Total Factor Energy Efficiency: Evidence from a Spatial Difference-in-Difference Method
Authors: Gao Da , Cao Yanjun , Liu Chang
Published: February 2023

In the post-epidemic background of the low-carbon economy and sustainable development, the low-carbon city pilot program (LCCP) is viewed as a practical method of improving energy efficiency. This study explores the spatial spillover effects of LCCP on green total factor energy efficiency (GTFEE) by developing a spatial difference-in-difference (SDID) model. Furthermore, we apply the mediating effects model to verify whether the rational allocation of resources is an influential channel for the spillover effect of LCCP policies. The results indicate that the LCCP policy has not only improved the local GTFEE by approximately 1.8%, but it also has a profound impact on the surrounding regions as well, which is about 76.5% that of the pilot cities. Additionally, the estimated results of the mediating effect model indicate that optimizing labor force and capital allocations are two essential channels through which the LCCP policy may contribute to improving regional cities’ GTFEE. Accordingly, the pilot cities should establish specific measures for rational resource allocation and promote the spatial spillover model of sustainable development.
Unpacking the Potential Influence of Life Satisfaction on Network Heterogeneity, Emotional Exhaustion and Mobile App Fatigue: A Stressor–Strain–Outcome Approach
Authors: Pang Hua , Shao Qinglong
Published: February 2023

The ramifications of mobile apps’ detrimental aspect on users’ life satisfaction have garnered increased attention from academics. To probe the underlying association between life satisfaction and mobile app fatigue, this article builds a research model based on a stressor–strain–outcome approach. In addition, the study investigates the relationships between different dimensions of network heterogeneity, emotional exhaustion, and mobile app fatigue among users. Furthermore, the study uncovers the moderating influence of upward comparison, self-presentation, and privacy invasion on the association between life satisfaction and emotional exhaustion in the mobile app context. The study collected data in mainland China using a cross-sectional approach and analyzed the data using structural equation modeling. The findings demonstrate that life satisfaction is positively associated with self-presentation and negatively associated with upward comparison. Moreover, privacy invasion and upward comparison are positively correlated with emotional exhaustion, whilst self-presentation exerts no correlation with emotional exhaustion. Furthermore, upward comparison could mediate the association between life satisfaction and emotional exhaustion. The results provide fresh light on the mechanisms through which the life satisfaction of mobile app users and network heterogeneity might lead to emotional exhaustion and mobile app fatigue, highlighting important theoretical and practical implications.
Structural Biology Inspired Development of a Series of Human Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Ligands: From Agonist to Antagonist
Authors: Miyachi Hiroyuki
Published: February 2023

Recent progress in the structural and molecular pharmacological understanding of the nuclear receptor, peroxisome proliferator-activated receptor gamma (hPPARγ)—a transcription factor with pleiotropic effects on biological responses—has enabled the investigation of various graded hPPARγ ligands (full agonist, partial agonist, and antagonist). Such ligands are useful tools to investigate the functions of hPPARγ in detail and are also candidate drugs for the treatment of hPPARγ-mediated diseases, such as metabolic syndrome and cancer. This review summarizes our medicinal chemistry research on the design, synthesis, and pharmacological evaluation of a covalent-binding and non-covalent-binding hPPARγ antagonist, both of which have been created based on our working hypothesis of the helix 12 (H12) holding induction/inhibition concept. X-ray crystallographic analyses of our representative antagonists complexed with an hPPARγ ligand binding domain (LBD) indicated the unique binding modes of hPPARγ LBD, which are quite different from the binding modes observed for hPPARγ agonists and partial agonists.
Time–Temperature Superposition Principle in Shearing Tests Compared to Tension Conditions for Polymers Close to Glass Transition
Authors: Billon Noëlle , Federico Carlos Eloy , Rival Guilhem , Bouvard Jean Luc , Burr Alain
Published: February 2023

The well-known principle of time–temperature superposition (TTS) is of prime interest for polymers close to their glass transition. First demonstrated in the range of linear viscoelasticity, it has been more recently extended to large deformations in tension. However, shear tests were not yet addressed. The present study depicted TTS in shearing conditions and compared it to results in tensile conditions both for low and high strains for a polymethylmethacrylate (PMMA) of different molar masses. The main objectives were to enlighten the relevance of the principle of time–temperature superposition for shearing at high strain and to discuss the way shift factors should be determined. It was suggested that shift factors could be dependent on compressibility, which should be taken into account when addressing various types of complex mechanical loadings.
Transcriptomics and Selection Pressure Analysis Reveals the Influence Mechanism of PLIN1 Protein on the Development of Small Size in Min Pigs
Authors: Liu Qiao , Yu Liqun , Zhang Ziwen , Chang Yang , Liu Zhonghua , Xu Chunzhu
Published: February 2023

Body size is an important biological phenotypic trait that has attracted substantial attention. Small domestic pigs can serve as excellent animal models for biomedicine and also help meet sacrificial culture needs in human societies. Although the mechanisms underlying vertebral development regulating body size variation in domestic pigs during the embryonic period have been well described, few studies have examined the genetic basis of body size variation in post embryonic developmental stages. In this study, seven candidate genes—PLIN1, LIPE, PNPLA1, SCD, FABP5, KRT10 and IVL—significantly associated with body size were identified in Min pigs, on the basis of weighted gene co-expression network analysis (WGCNA), and most of their functions were found to be associated with lipid deposition. Six candidate genes except for IVL were found to have been subjected to purifying selection. PLIN1 had the lowest ω value (0.139) and showed heterogeneous selective pressure among domestic pig lineages with different body sizes (p < 0.05). These results suggested that PLIN1 is an important genetic factor regulating lipid deposition and consequently affecting body size variation in pigs. The culture of whole pig sacrifice in Manchu during the Qing Dynasty in China might have contributed to the strong artificial domestication and selection of Hebao pigs.