bluuebunny/crossref_metadata_2025 huggingface dataset:
Biological behaviour of human umbilical artery smooth muscle cell grown on nickel-free and nickel-containing stainless steel for stent implantation
Authors: Li Liming , An Liwen , Zhou Xiaohang , Pan Shuang , Meng Xin , Ren Yibin , Yang Ke , Guan Yifu
Published: January 2016

To evaluate the clinical potential of high nitrogen nickel-free austenitic stainless steel (HNNF SS), we have compared the cellular and molecular responses of human umbilical artery smooth muscle cells (HUASMCs) to HNNF SS and 316L SS (nickel-containing austenitic 316L stainless steel). CCK-8 analysis and flow cytometric analysis were used to assess the cellular responses (proliferation, apoptosis and cell cycle) and quantitative real-time PCR (qRT-PCR) was used to analyze the gene expression profiles of HUASMCs exposed to HNNF SS and 316L SS, respectively. CCK-8 analysis demonstrated that HUASMCs cultured on HNNF SS proliferated more slowly than those on 316L SS. Flow cytometric analysis revealed that HNNF SS could activate more cellular apoptosis. The qRT-PCR results showed that the genes regulating cell apoptosis and autophagy were up-regulated on HNNF SS. Thus, HNNF SS could reduce the HUASMC proliferation in comparison to 316L SS. The findings furnish valuable information for developing new biomedical materials for stent implantation.
Utilization of native oxygen in Eu(RE)-doped GaN for enabling device compatibility in optoelectronic applications
Authors: Mitchell B. , Timmerman D. , Poplawsky J. , Zhu W. , Lee D. , Wakamatsu R. , Takatsu J. , Matsuda M. , Guo W. , Lorenz K. , Alves E. , Koizumi A. , Dierolf V. , Fujiwara Y.
Published: January 2016

The detrimental influence of oxygen on the performance and reliability of V/III nitride based devices is well known. However, the influence of oxygen on the nature of the incorporation of other co-dopants, such as rare earth ions, has been largely overlooked in GaN. Here, we report the first comprehensive study of the critical role that oxygen has on Eu in GaN, as well as atomic scale observation of diffusion and local concentration of both atoms in the crystal lattice. We find that oxygen plays an integral role in the location, stability and local defect structure around the Eu ions that were doped into the GaN host. Although the availability of oxygen is essential for these properties, it renders the material incompatible with GaN-based devices. However, the utilization of the normally occurring oxygen in GaN is promoted through structural manipulation, reducing its concentration by 2 orders of magnitude, while maintaining both the material quality and the favorable optical properties of the Eu ions. These findings open the way for full integration of RE dopants for optoelectronic functionalities in the existing GaN platform.
FTO modulates fibrogenic responses in obstructive nephropathy
Authors: Wang Chao-Yung , Shie Shian-Sen , Tsai Ming-Lung , Yang Chia-Hung , Hung Kuo-Chun , Wang Chun-Chieh , Hsieh I-Chang , Wen Ming-Shien
Published: January 2016

Genome-wide association studies have shown that variants in fat mass and obesity-associated (FTO) gene are robustly associated with body mass index and obesity. These FTO variants are also associated with end stage renal disease and all-cause mortality in chronic kidney diseases. However, the exact role of FTO in kidneys is currently unknown. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis. Deficiency of the FTO gene attenuates the fibrogenic responses induced by ureteral obstruction in the kidney. Renal tubular cells deficient of FTO produce less α-SMA after TGF-β stimulation. FTO is indispensable for the extracellular matrix synthesis after ureteral obstruction in kidneys. Indeed, global gene transcriptions amplitude is reduced in FTO deficient kidneys after ureteral obstruction. These data establish the importance of FTO in renal fibrosis, which may have potential therapeutic implications.
Porous honeycomb structures formed from interconnected MnO2 sheets on CNT-coated substrates for flexible all-solid-state supercapacitors
Authors: Ko Wen-Yin , Chen You-Feng , Lu Ke-Ming , Lin Kuan-Jiuh
Published: January 2016

The use of lightweight and easily-fabricated MnO2/carbon nanotube (CNT)-based flexible networks as binder-free electrodes and a polyvinyl alcohol/H2SO4 electrolyte for the formation of stretchable solid-state supercapacitors was examined. The active electrodes were fabricated from 3D honeycomb porous MnO2 assembled from cross-walled and interconnected sheet-architectural MnO2 on CNT-based plastic substrates (denoted as honeycomb MnO2/CNT textiles).These substrates were fabricated through a simple two-step procedure involving the coating of multi-walled carbon nanotubes (MWCNTs) onto commercial textiles by a dipping-drying process and subsequent electrodeposition of the interconnected MnO2 sheets onto the MWCNT-coated textile. With such unique MnO2 architectures integrated onto CNT flexible films, good performance was achieved with a specific capacitance of 324 F/g at 0.5 A/g. A maximum energy density of 7.2 Wh/kg and a power density as high as 3.3 kW/kg were exhibited by the honeycomb MnO2/CNT network device, which is comparable to the performance of other carbon-based and metal oxide/carbon-based solid-state supercapacitor devices. Specifically, the long-term cycling stability of this material is excellent, with almost no loss of its initial capacitance and good Coulombic efficiency of 82% after 5000 cycles. These impressive results identify these materials as a promising candidate for use in environmentally friendly, low-cost and high-performance flexible energy-storage devices.
A novel label-free fluorescence strategy for methyltransferase activity assay based on dsDNA-templated copper nanoparticles coupled with an endonuclease-assisted signal transduction system
Authors: Lai Q. Q. , Liu M. D. , Gu C. C. , Nie H. G. , Xu X. J. , Li Z. H. , Yang Z. , Huang S. M.
Published: January 2016

A novel label-free fluorescence method by coupling dsDNA-templated CuNPs with endonuclease-assisted signal transduction has been developed for methyltransferase activity assay.
Raman microscopy at the subcellular level: a study on early apoptosis in endothelial cells induced by Fas ligand and cycloheximide
Authors: Czamara Krzysztof , Petko Filip , Baranska Malgorzata , Kaczor Agnieszka
Published: January 2016

Raman microscopy of endothelial EA.hy926 cells upon stimulation by Fas ligand and cycloheximide is reported. The analysis enabled characterization of the chemical and structural changes in the early stage of apoptosis.
Thermal ionisation mass spectrometry (TIMS) in nuclear science and technology – a review
Authors: Aggarwal Suresh K.
Published: January 2016

The advances which have taken place during the last four decades in the instrumentation and applications of thermal ionisation mass spectrometry (TIMS) particularly of relevance to nuclear science and technology are highlighted.
Electrochemical sensing of levodopa or carbidopa using a glassy carbon electrode modified with carbon nanotubes within a poly(allylamine hydrochloride) film
Authors: Takeda Humberto Hissashi , Silva Tiago Almeida , Janegitz Bruno Campos , Vicentini Fernando Campanhã , Capparelli Mattoso Luiz Henrique , Fatibello-Filho Orlando
Published: January 2016

A carbon nanotube-based sensor is proposed for the voltammetric sensing of levodopa or carbidopa in different samples.
Rhodium-catalyzed annulation of arenes with alkynes through weak chelation-assisted C–H activation
Authors: Yang Yudong , Li Kaizhi , Cheng Yangyang , Wan Danyang , Li Mingliang , You Jingsong
Published: January 2016

This feature article reviews the recent achievements of rhodium-catalyzed annulation of arenes with alkynes through weak chelation-assisted C–H activation, which sets a stage for the synthesis of diverse appealing polycyclic compounds.
Thermally induced formal [3+2] cyclization of ortho-aminoaryl-tethered alkylidenecyclopropanes: facile synthesis of furoquinoline and thienoquinoline derivatives
Authors: Yu Liu-Zhu , Hu Xu-Bo , Xu Qin , Shi Min
Published: January 2016

Thermally induced formal [3+2] cycloaddition reactions of alkylidenecyclopropanes with the in situ generation of isocyanates and isothiocyanates have been developed.
Discovery of a non classic host guest complexation mode in a β-cyclodextrin/propionic acid model
Authors: Rutenberg R. , Leitus G. , Fallik E. , Poverenov E.
Published: January 2016

A non-classic complexation mode was discovered using a β-cyclodextrin/propionic acid model. A “fully immersed” complexation phenomenon was found in which both the guest's hydrophobic and polar moieties are located inside the host and are stabilized by it. This configuration was also found to be the most favorable and probable.
Cobalt(iii)-catalyzed alkenylation of arenes and 6-arylpurines with terminal alkynes: efficient access to functional dyes
Authors: Wang Shan , Hou Ji-Ting , Feng Mei-Lin , Zhang Xiao-Zhuan , Chen Shan-Yong , Yu Xiao-Qi
Published: January 2016

A method for cobalt(iii)-catalyzed alkenylation of arenes and 6-arylpurines has been developed. This reaction takes place under mild conditions with only equivalent terminal alkynes in high yields. A mitochondria-targeted imaging dye was simply prepared through this method.
Facile fabrication of freestanding three-dimensional composites for supercapacitors
Authors: Li Xiaoyan , Wang Jun , Ge Fengyan , Komarneni Sridhar , Cai Zaisheng
Published: January 2016

Flexible three-dimensional composites of carbon nanofibers with ZnO for supercapacitor electrodes.
Post-synthetic metalation in an anionic MOF for efficient catalytic activity and removal of heavy metal ions from aqueous solution
Authors: Chakraborty Anindita , Bhattacharyya Sohini , Hazra Arpan , Ghosh Ashta Chandra , Maji Tapas Kumar
Published: January 2016

An anionic MOF shows the potential to capture toxic metal ions from water and the CuII@AMOF hybrid obtained through post-synthetic metalation is used as a Lewis acid catalyst.
An enantioselective three-component reaction of diazoacetates with indoles and enals by iridium/iminium co-catalysis
Authors: Li Mingfeng , Guo Xin , Jin Weifeng , Zheng Qing , Liu Shunying , Hu Wenhao
Published: January 2016

The first example of chiral secondary amine and iridium(i) co-catalyzed enantioselective three-component reaction of aryldiazoacetates, indoles and enals was rationally designed and developed to afford 3-substituted indoles in good yields and with excellent enantioselectivity.
Bromomethyllithium-mediated chemoselective homologation of disulfides to dithioacetals
Authors: Pace Vittorio , Pelosi Azzurra , Antermite Daniele , Rosati Ornelio , Curini Massimo , Holzer Wolfgang
Published: January 2016

Dithioacetals from disulfidesviahomologation.
Excited state structural evolution during charge-transfer reactions in betaine-30
Authors: Ruchira Silva W. , Frontiera Renee R.
Published: January 2016

Ultrafast photo-induced charge-transfer reactions are fundamental to a number of photovoltaic and photocatalytic devices, yet the multidimensional nature of the reaction coordinate makes these processes difficult to model theoretically.
Substituent effect and wavelength dependence of the photoinduced Ru–O homolysis in the [Ru(bpy)2(py-SO3)]+-type complexes
Authors: Zheng Yue , Zhou Qian-Xiong , Zhang Yang-Yang , Li Chao , Hou Yuan-Jun , Wang Xue-Song
Published: January 2016

Electron-withdrawing substituents on bpy ligands improve the photoinduced Ru–O homolysis in the [Ru(bpy)2(py-SO3)]+-type complexes.
Lanthanide salen-type complexes exhibiting single ion magnet and photoluminescent properties
Authors: Ren Min , Xu Zhong-Li , Bao Song-Song , Wang Ting-Ting , Zheng Ze-Hua , Ferreira Rute A. S. , Zheng Li-Min , Carlos Luis D.
Published: January 2016

Mononuclear lanthanide complexes with formula (Et3NH)[Ln(3-NO2-salen)2]·solvent (Ln = Eu (1Eu), Tb (2Tb), Dy (3Dy), Ho (4Ho), Er (5Er), Yb (6Yb); 3-NO2-salen2− = N,N′-bis(3-nitro-salicylaldehyde)ethylenediamine dianion) are reported.
Oxidase-like mimic of Ag@Ag3PO4 microcubes as a smart probe for ultrasensitive and selective Hg2+ detection
Authors: Chai Dong-Feng , Ma Zhuo , Qiu Yunfeng , Lv Yu-Guang , Liu Hong , Song Chao-Yu , Gao Guang-Gang
Published: January 2016

An oxidase-like mimic system based on facilely synthesized Ag@Ag3PO4 microcubes (Ag@Ag3PO4MCs) was designed and utilized to detect mercury ions with high selectivity and ultrasensitivity.
Synthesis, characterization, and H/D exchange of μ-hydride-containing [FeFe]-hydrogenase subsite models formed by protonation reactions of (μ-TDT)Fe2(CO)4(PMe3)2 (TDT = SCH2SCH2S) with protic acids
Authors: Song Li-Cheng , Zhu An-Guo , Guo Yuan-Qiang
Published: January 2016

The first TDT ligand-containing μ-hydride models of [FeFe]-hydrogenases (2–7) have been prepared and the H/D exchange reactions of 7 with deuterium reagents such as D2, D2O, and DCl are studied.
Substituent effects on fluoride binding by lanthanide complexes of DOTA-tetraamides
Authors: Blackburn Octavia A. , Routledge Jack D. , Jennings Laura B. , Rees Nicholas H. , Kenwright Alan M. , Beer Paul D. , Faulkner Stephen
Published: January 2016

Fluoride binding by lanthanide complexes of a range of DOTA tetraamides changes the magnetic anisotropy at the metal centre from an easy axis to an easy plane.
Fluorescent asymmetric bis-ureas for pyrophosphate recognition in pure water
Authors: Casula Arianna , Bazzicalupi Carla , Bettoschi Alexandre , Cadoni Enzo , Coles Simon J. , Horton Peter N. , Isaia Francesco , Lippolis Vito , Mapp Lucy K. , Marini Giada M. , Montis Riccardo , Scorciapino Mariano Andrea , Caltagirone Claudia
Published: January 2016

Fluorescent asymmetric bis-ureas are able to recognize HPpi3− in water.
Hollow-structured Si/SiC@C nanospheres as highly active catalysts for cycloaddition of epoxides with CO2 under mild conditions
Authors: Liu Mei-Pin , Luo Yan-Ping , Xu Lei , Sun Lin , Du Hong-Bin
Published: January 2016

Hollow-structured Si/SiC@C nanospheres, prepared through magnesiothermic reduction, exhibit excellent catalytic activities for chemical fixation of CO2 under mild, solvent-free conditions.
Solvent triggered structural diversity of triple-stranded helicates: single molecular magnets
Authors: Li Hongfeng , Chen Peng , Sun Wenbin , Zhang Lei , Yan Pengfei
Published: January 2016

Solvents have been found to be the key for the construction of diverse triple-stranded helicates. Distinct solvent molecules are found to coordinate to the Dy3+ centers to replace the original hydrate molecules.
Disclosing the multi-faceted world of weakly interacting inorganic systems by means of NMR spectroscopy
Authors: Rocchigiani Luca , Macchioni Alceo
Published: January 2016

The potential of NMR spectroscopy to investigate inorganic systems whose structure and reactivity is affected by non-covalent interactions is described; supramolecular assemblies based on relatively unusual intermolecular forces or on more classical ones, still rather unexplored in solution, are considered.
Platinum carbonyl clusters stabilized by Sn(ii)-based fragments: syntheses and structures of [Pt6(CO)6(SnCl2)2(SnCl3)4]4−, [Pt9(CO)8(SnCl2)3(SnCl3)2(Cl2SnOCOSnCl2)]4−and [Pt10(CO)14{Cl2Sn(OH)SnCl2}2]2−
Authors: Bortoluzzi Marco , Ceriotti Alessandro , Ciabatti Iacopo , Della Pergola Roberto , Femoni Cristina , Carmela Iapalucci Maria , Storione Alba , Zacchini Stefano
Published: January 2016

Low valent Pt carbonyl clusters decorated by Sn(ii) fragments have been obtained from [Pt15(CO)30]2−and SnCl2.
A simple but efficient strategy to enhance hydrostability of intensely fluorescent Mg-based coordination polymer (CP) via forming a composite of CP with hydrophobic PVDF
Authors: Zhai Lu , Zhang Wen-Wei , Zuo Jing-Lin , Ren Xiao-Ming
Published: January 2016

The composites of 1 with hydrophobic PVDF were prepared by mechanically mixed, tableted and annealed approach, which showed good compatibility between 1 and PVDF, high hydrostability and intense blue emission.
Enhanced UV-light stability of planar heterojunction perovskite solar cells with caesium bromide interface modification
Authors: Li Wenzhe , Zhang Wei , Van Reenen Stephan , Sutton Rebecca J. , Fan Jiandong , Haghighirad Amir A. , Johnston Michael B. , Wang Liduo , Snaith Henry J.
Published: January 2016

CsBr interface modification simultaneously enhances the device power conversion efficiency and improves the device resilience to UV irradiation.
Thermally rearranged polymer membranes for desalination
Authors: Kim Ji Hoon , Park Sang Hyun , Lee Moon Joo , Lee Sang Min , Lee Won Hyo , Lee Kang Hyuck , Kang Na Rae , Jo Hye Jin , Kim Jeong F. , Drioli Enrico , Lee Young Moo
Published: January 2016

Thermally rearranged polybenzoxazole-co-imide (TR-PBOI) membranes exhibited excellent flux (80 kg m2 h−1) and salt rejection (>99.99%) over more than 186 hours as well as potential for use in membrane crystallization.
Sialoglycoproteins prepared from the eggs of Carassius auratus prevent bone loss by inhibiting the NF-κB pathway in ovariectomized rats
Authors: Xia Guanghua , Wang Jingfeng , Sun Shuhong , Zhao Yanlei , Wang Yiming , Yu Zhe , Wang Shanshan , Xue Changhu
Published: January 2016

Improved osteoporosis by inhibiting osteoclastogenesis via suppressing the activation of the OPG/RANKL/RANK pathway.
An improved course of glycaemia after a bread based breakfast is associated with beneficial effects on acute and semi-acute markers of appetite
Authors: Ekström Linda M. N. K. , Björck Inger M. E. , Östman Elin M.
Published: January 2016

A breakfast giving low and sustained glycaemia results in beneficial effects on appetite, both acute and after a subsequentad libmeal.
Recyclable organocatalysts based on hybrid silicas
Authors: Ferré M. , Pleixats R. , Wong Chi Man M. , Cattoën X.
Published: January 2016

Review on organosilica-based materials in supported organocatalysis.
Hydrolytic liquefaction of hydrolysis lignin for the preparation of bio-based rigid polyurethane foam
Authors: Mahmood Nubla , Yuan Zhongshun , Schmidt John , Tymchyshyn Matthew , Xu Chunbao (Charles)
Published: January 2016

Hydrolysis lignin (HL) was liquefied employing 50/50 (v/v) water–ethanol mixture for the preparation of bio-based polyols/rigid polyurethane foams.
Computational identification and analysis of signaling subnetworks with distinct functional roles in the regulation of TNF production
Authors: Tomaiuolo Maurizio , Kottke Melissa , Matheny Ronald W. , Reifman Jaques , Mitrophanov Alexander Y.
Published: January 2016

We developed, validated, and analyzed a computational model of the signaling network controlling the production of the essential pro-inflammatory cytokine TNF and its anti-inflammatory counterpart IL-10.
N,N′-Disubstituted thiourea and urea derivatives: design, synthesis, docking studies and biological evaluation against nitric oxide synthase
Authors: Chayah Mariem , Camacho M. Encarnación , Carrión M. Dora , Gallo Miguel A. , Romero Miguel , Duarte Juan
Published: January 2016

N,N′-Disubstituted thioureas and ureas as nNOS and iNOS inhibitors were synthesized. Thiourea 4g was the best inhibitor without eNOS inhibition.
Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature?
Authors: Glaser J. , Holzgrabe U.
Published: January 2016

Pan-assay interference compounds (PAINS) are molecules showing promising but deceptive activities in various biochemical screenings mainly due to unselective interactions with the target.
Investigation of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents: novel Akt/PKB signaling pathway inhibitors
Authors: Nagarsenkar Atulya , Prajapti Santosh Kumar , Guggilapu Sravanthi Devi , Birineni Swetha , Sravanti Kotapalli Sudha , Ummanni Ramesh , Babu Bathini Nagendra
Published: January 2016

Novel triazole-linked indole and oxindole glycoconjugates as inhibitors of the Akt/PKB signaling pathway.
Sterically shielded blue thermally activated delayed fluorescence emitters with improved efficiency and stability
Authors: Zhang Dongdong , Cai Minghan , Zhang Yunge , Zhang Deqiang , Duan Lian
Published: January 2016

Devices utilizing sterically shielded blue thermally activated delayed fluorescence emitters achieve high efficiencies and long lifetimes simultaneously.
Exploiting the biological windows: current perspectives on fluorescent bioprobes emitting above 1000 nm
Authors: Hemmer Eva , Benayas Antonio , Légaré François , Vetrone Fiorenzo
Published: January 2016

Rare-earth based nanoparticles, Group-IV nanostructures, and novel quantum dots in the near-infrared (NIR) spotlight: current trends, material merits, and latest developments in NIR-to-NIR bioimaging.
A graphene oxide immobilized Cu(ii) complex of 1,2-bis(4-aminophenylthio)ethane: an efficient catalyst for epoxidation of olefins with tert-butyl hydroperoxide
Authors: Zarnegaryan Ali , Moghadam Majid , Tangestaninejad Shahram , Mirkhani Valiollah , Mohammdpoor-Baltork Iraj
Published: January 2016

Alkene epoxidation with tert-butyl hydroperoxide catalyzed by the Cu(ii) dithiol complex supported on graphene oxide is reported.
Protein adsorption induced bridging flocculation: the dominant entropic pathway for nano-bio complexation
Authors: Eren Necla Mine , Narsimhan Ganesan , Campanella Osvaldo H.
Published: January 2016

Free energy of nano-bio complexation was decoupled into entropic and enthalpic contributions.
Electron beam controlled covalent attachment of small organic molecules to graphene
Authors: Markevich Alexander , Kurasch Simon , Lehtinen Ossi , Reimer Oliver , Feng Xinliang , Müllen Klaus , Turchanin Andrey , Khlobystov Andrei N. , Kaiser Ute , Besley Elena
Published: January 2016

Electron beam induced covalent attachment of the radicals of polyaromatic molecules to graphene is studied computationally and using transmission electron microscopy.
The effect of the degree of oxidation on broadband nonlinear absorption and ferromagnetic ordering in graphene oxide
Authors: Liaros Nikos , Tucek Jiri , Dimos Konstantinos , Bakandritsos Aristides , Andrikopoulos Konstantinos S. , Gournis Dimitrios , Zboril Radek , Couris Stelios
Published: January 2016

The broadband nonlinear absorption increases with less oxidized/reduced graphene oxides, while the Curie temperature and magnetic response in the ferromagnetic state increases with the degree of oxidation.
Experimental and theoretical investigation of a mesoporous KxWO3material having superior mechanical strength
Authors: Dey Sonal , Anderson Sean T. , Mayanovic Robert A. , Sakidja Ridwan , Landskron Kai , Kokoszka Berenika , Mandal Manik , Wang Zhongwu
Published: January 2016

Potassium incorporation along intercalation sites leads to a robust tungsten oxide mesoporous materialviathe formation of an orthogonal tungsten bronze phase.
Synthesis of substituted benzo[ij]imidazo[2,1,5-de]quinolizine by rhodium(iii)-catalyzed multiple C–H activation and annulations
Authors: Ge Qingmei , Li Bin , Wang Baiquan
Published: January 2016

The cascade oxidative annulation reactions of aryl imidazoles with two molecules of alkynesviamultiple C–H activation proceed efficiently in the presence of [Cp*RhCl2]2and Cu(OAc)2·H2O to give substituted benzo[ij]imidazo[2,1,5-de]quinolizine-based polyheteroaromatic compounds.
Ultra-large sheet formation by 1D to 2D hierarchical self-assembly of a “rod–coil” graft copolymer with a polyphenylene backbone
Authors: Huang Yinjuan , Yuan Rui , Xu Fugui , Mai Yiyong , Feng Xinliang , Yan Deyue
Published: January 2016

This study presents a unique ultra-large sheet formation through 1D to 2D hierarchical self-assembly of a rod–coil graft copolymer containing a rigid polyphenylene backbone tethered with flexible poly(ethylene oxide) side chains.
The effect of the support structure on catalytic activity: a case study on hollow and solid MoO3/SiO2
Authors: Wang Jiasheng , Liu Hong
Published: January 2016

Hollow and solid MoO3/SiO2 nanocomposites were synthesized in reverse microemulsion. Due to its bigger surface area, shorter pore channels and thus less travelling blockage, the hollow support showed better catalytic performance than the solid one.
Density functional theory study of hydrogenation of S to H2S on Pt–Pd alloy surfaces
Authors: Liu Yunjie , Guo Wenyue , Lu Xiaoqing , Gao Wei , Li Guixia , Guo Yahui , Zhu Jun , Hao Lanzhong
Published: January 2016

In this work, the adsorption of S-containing species (S, HS, and H2S) and the hydrogenation of S on the Pt–Pd alloy were investigated by using the periodic density functional theory (DFT).
A metal-free synthetic approach to peptide-based iminosugar clusters as novel multivalent glycosidase inhibitors
Authors: Zelli Renaud , Bartolami Eline , Longevial Jean-François , Bessin Yannick , Dumy Pascal , Marra Alberto , Ulrich Sébastien
Published: January 2016

Oxime ligation allowed the preparation of a set of iminosugar clusters from which new Jack bean α-mannosidase inhibitors were identified.
A horseradish peroxidase immobilized radiation grafted polymer matrix: a biocatalytic system for dye waste water treatment
Authors: Kumar Virendra , Misra Nilanjal , Goel Narender Kumar , Thakar Rucha , Gupta Jagannath , Varshney Lalit
Published: January 2016

A single step-environment friendly-water based-radiation grafting process was used to fabricate an epoxy functionalized polymer support for one step-covalent immobilization of enzyme HRP in ambient conditions, and tested for dye waste water treatment.
Biopolymer-based electrolyte membranes from chitosan incorporated with montmorillonite-crosslinked GPTMS for direct methanol fuel cells
Authors: Purwanto Mochammad , Atmaja Lukman , Mohamed Mohamad Azuwa , Salleh M. T. , Jaafar Juhana , Ismail A. F. , Santoso Mardi , Widiastuti Nurul
Published: January 2016

A composite membrane was fabricated from biopolymer chitosan and montmorillonite (MMT) filler as an alternative membrane electrolyte for direct methanol fuel cell (DMFC) application.
Fabrication of a mercury(ii) ion selective electrode based on poly-o-toluidine–zirconium phosphoborate
Authors: Kaushal Sandeep , Badru Rahul , Kumar Sanjeev , Mittal Susheel K. , Singh Pritpal
Published: January 2016

This work covers various aspects of a new ion selective electrode for mercury(ii) ions, designed by incorporation of poly-o-toluidine (PTD) into zirconium phosphoborate (ZrPB) ion exchanger.
Fatty acid ionic liquids as environmentally friendly lubricants for low friction and wear
Authors: Gusain Rashi , Khatri Om P.
Published: January 2016

Tetrabutylammonium-fatty acids ionic liquids as lubricants exhibited significantly lower friction compared to polyol ester lube base oil.
Theoretical insights into the CO dimerization and trimerization on Pt nanocluster
Authors: Yang Yongpeng , Cheng Ping , Zhang Shengli , Huang Shiping
Published: January 2016

CO dimerizaiton and trimerization on icosahedral Pt55cluster.
Nickel(ii)-catalyzed enantioselective cyclopropanation of 3-alkenyl-oxindoles with phenyliodonium ylide via free carbene
Authors: Guo Jing , Liu Yangbin , Li Xiangqiang , Liu Xiaohua , Lin Lili , Feng Xiaoming
Published: January 2016

A chiral Lewis acid-promoted cyclopropanation using a phenyliodonium ylide as the carbene precursor was developed. An EPR spectroscopy study supported a stepwise biradical mechanism.
Catalysis by framework zinc in silica-based molecular sieves
Authors: Orazov Marat , Davis Mark E.
Published: January 2016

Adjustable Zn Lewis acid site distributions in crystalline, microporous zincosilicates were studied spectroscopically and explored for catalytic applications.
Combining photochemistry and catalysis: rapid access to sp3 – rich polyheterocycles from simple pyrroles
Authors: Blackham Emma E. , Knowles Jonathan P. , Burgess Jonathan , Booker-Milburn Kevin I.
Published: January 2016

The powerful combination of photochemistry and catalysis transforms simple pyrroles into complex polycyclic structures in just two steps. Initial formation of highly reactive aziridines enables new Pd-catalysed cascade sequences, forming a range of polyheterocycles including tricyclic β-lactams.
DNA orientation-specific adhesion and patterning of living mammalian cells on self-assembled DNA monolayers
Authors: Wang Shaopeng , Cai Xiaoqing , Wang Lihua , Li Jiang , Li Qian , Zuo Xiaolei , Shi Jiye , Huang Qing , Fan Chunhai
Published: January 2016

DNA orientation-specific adhesion and patterning of living mammalian cells on self-assembled DNA monolayers.
Direct and multiplex quantification of protein biomarkers in serum samples using an immuno-magnetic platform
Authors: Ho See-Lok , Xu Di , Wong Man Shing , Li Hung-Wing
Published: January 2016

A direct and ultrasensitive multiplex assay using an immuno-magnetic platform has been developed for the quantification of trace amounts of circulating cancer-associated antigens in serum.
Simple and ultrastable all-inclusive pullulan tablets for challenging bioassays
Authors: Jahanshahi-Anbuhi Sana , Kannan Balamurali , Leung Vincent , Pennings Kevin , Liu Meng , Carrasquilla Carmen , White Dawn , Li Yingfu , Pelton Robert H. , Brennan John D. , Filipe Carlos D. M.
Published: January 2016

A glowing example: simple to use, highly stable and cost-effective luciferase/luciferin assays using rapidly solubilizing pullulan tablets.
Isolation of Au-, Co-η1PCO and Cu-η2PCO complexes, conversion of an Ir–η1PCO complex into a dimetalladiphosphene, and an interaction-free PCO anion
Authors: Liu Liu Leo , Ruiz David A. , Dahcheh Fatme , Bertrand Guy , Suter Riccardo , Tondreau Aaron M. , Grützmacher Hansjörg
Published: January 2016

Sodium phosphaethynolate reacts with [MCl(PDI)] (M = Co, Ir; PDI = pyridinediimine) to give metallaphosphaketenes, which in the case of iridium rearranges into a dimetalladiphosphene.
Buckling of an elastic fiber with finite length in a soft matrix
Authors: Zhao Yan , Li Jing , Cao Yan Ping , Feng Xi-Qiao
Published: January 2016

Elastic fibers with finite length embedded in soft substrates are ubiquitous in both nature and engineering. In these systems, compression is usually applied to the soft matrix rather than imposed on the fibers directly. The fiber senses the compression through interfacial shear. An analytical solution is derived to predict the critical compressive strain for the buckling of the fiber.
Studies on thermoelectric figure of merit of Na-doped p-type polycrystalline SnSe
Authors: Chere Eyob K. , Zhang Qian , Dahal Keshab , Cao Feng , Mao Jun , Ren Zhifeng
Published: January 2016

Na doping improved both the peak and average ZT of p-type polycrystalline SnSe.
Monodisperse and self-assembled Pt-Cu nanoparticles as an efficient electrocatalyst for the methanol oxidation reaction
Authors: Du Xuewei , Luo Shuiping , Du Hongyu , Tang Min , Huang Xiangdong , Shen Pei Kang
Published: January 2016

Monodisperse PtCu nanoparticles have been synthesized and can be self-assembled via adding oleylamine (OAM), and they show higher activity, stability and better CO tolerance compared with Pt/C toward the methanol oxidation reaction.
Highly efficient low temperature solution processable planar type CH3NH3PbI3 perovskite flexible solar cells
Authors: Heo Jin Hyuck , Lee Min Ho , Han Hye Ji , Patil Basavaraj Rudragouda , Yu Jae Su , Im Sang Hyuk
Published: January 2016

A highly efficient PEN/ITO/ZnO/CH3NH3PbI3 perovskite/PTAA/Au flexible planar solar cell with 1.1 V Voc, 18.7 mA cm−2Jsc, 75% FF, and 15.4% η for the forward scan direction and 1.1 V Voc, 18.7 mA cm−2Jsc, 76% FF and 15.6% η for the reverse scan direction under illumination of 1 Sun was demonstrated.
Highly efficient dye-sensitized solar cells based on a ruthenium sensitizer bearing a hexylthiophene modified terpyridine ligand
Authors: Ozawa Hironobu , Sugiura Takahito , Kuroda Takahiro , Nozawa Kouya , Arakawa Hironori
Published: January 2016

An extremely high conversion efficiency (11.9%) can be achieved for a dye-sensitized solar cell with a ruthenium sensitizer (TUS-38) by optimizing the dye-adsorption conditions and the electrolyte composition.
Evaluating patterns of human–reptile conflicts in an urban environment
Authors: Teixeira Camila Palhares , Passos Luiza , Goulart Vinicius D. L. R. , Hirsch Andre , Rodrigues Marcos , Young Robert J.
Published: January 2016

Context Reptiles, especially snakes, can cause a fear reaction in the public and are, therefore, a good model to examine human–wildlife conflicts. Human city dwellers often respond to the presence of snakes or other reptiles by calling out the responsible agency for animal control, which has to mediate the situation. Aims To determine how the temporal and spatial occurrence of human–reptile conflicts were associated with environmental conditions and socio-economic factors in a large Brazilian city (Belo Horizonte). Methods The callout reports of the Environmental Police of Belo Horizonte, Brazil, over a 7-year period from 2002 to 2008 to mediate reptile conflicts were analysed. Densities of callouts were determined by kernel-density estimator and matched with the vegetation cover and land use, to determine how the environment affected reptile callout distribution. The study area was divided into nine regions with different socio-economic and demographic characteristics to evaluate the possible effects of human factors in the conflict. Key results Reptile callouts were almost exclusively about snakes or freshwater turtles, despite a large population of wild lizards. In general, the difference in callout distribution of snakes and freshwater turtles was the result of different attitudes from city dwellers on the basis of socio-economic characteristics. Snakes were less frequent as urbanisation increased, whereas freshwater turtles were associated with water or open areas. Significantly, more conflicts occurred during the rainy season. People in areas of high per capita income used the Environmental Police as mediators more often than did those in poorer areas, but callouts were not related to human population density. Conclusions Habitat type and climate were significantly predictive of human–reptile conflicts. Human populations with higher salaries and education levels tended to resolve their conflicts with reptiles using official mediators whether the reptile was venomous or not. Implications The environmental and climatic data show that it is possible to predict when and where human–reptile conflicts are most likely. Thus, official mediators can use this information for targeted education programs. Such education programs should emphasise, at all levels of society, how to deal with such conflicts sensibly, so as to ensure the best outcomes for people and reptiles.
Hardness-load modelling applied to multilayer galvanised coatings
Authors: Benarioua Y. , Mejias A. , Roudet F. , Iost A. , Chicot D.
Published: January 2016

During the last past decades, galvanised steels have been extensively developed to improve corrosion resistance of steels due to their excellent chemical properties particularly in severe atmospheric conditions. The objective of this work is to predict the hardness-load variation in relation to the bath immersion time using both a multilayer coating hardness model and a layers growth modelling. The kinetic growth of each layer relates the thickness to the immersion time by a simple power law. The hardness of the intermetallic compounds is determined by applying a multilayer hardness model on classical Vickers microindentation data obtained at different indentation loads. Afterwards by combining the kinetic growth laws and the compounds hardness, it is possible to predict the surface hardness-load variation as a function of the immersion bath time.
Psychological Distress Among Older Prisoners: A Literature Review
Authors: Baidawi Susan , Totter Chris
Published: January 2016

Older people constitute the fastest growing age group among many prisoner populations worldwide, yet little is known about the mental wellbeing of this population. This article reviews research examining the level of psychological distress experienced by older prisoners, as well as the factors associated with this phenomenon. Findings suggest that older prisoners likely experience levels of psychological distress which are similar to that of younger prisoners and greater than that of older people in the general community. Personal, demographic, prison, and social factors associated with psychological distress are also identified from the literature and implications for future research are discussed.
Who is Most Likely to Graduate From Teen Court?
Authors: Gallagher John R. , Wahler Elizabeth , Marshall Brooke , Leiter Nicole , Deranek Mike , Harrington Lori
Published: January 2016

This article contributes to the literature by identifying variables that predicted graduation from an Indiana teen court. Findings indicated that interventions that are commonly used in teen courts to promote positive behavioral change, such as community service and jail tours, paradoxically predicted noncompletion of teen court. Specifically, youths who completed community service or jail tours were less likely to graduate than those who were not ordered to complete these interventions. Minority youths, those in special education, and having more violations throughout the program also show less likelihood of graduation. Implications for teen court practice and future research are discussed.
‘‘I Didn’t Know He Had It in Him to Kill Me’’: Non lethal Firearms Use and Partner Violence Against Canadian Women
Authors: TUTTY LESLIE
Published: January 2016

This qualitative research explored with women the nature and impact of non-lethal firearm-related assaults inflicted on  them by their male partners. Forty women from Alberta, Canada described incident(s) in which firearms were central, with 5 contextual themes emerging: (a) threats by partners to commit suicide with firearms(4 women); (b) indirect threats (6 women); (c) explicit threats to harm with a firearm without producing the weapon(11 women); (d) one traumatic incident involving firearms (12 women); and (e) firearm threats or used throughout the relationship (7 women). Practice and policy options are presented for forensic and clinical social workers, shelter workers, and police officers.
Lived Challenges to Ethical Social Work Practice in Criminal Justice Settings
Authors: Young Diane
Published: January 2016

Ethical social work practice within criminal justice settings is fraught with challenges. Through individual interviews in a qualitative study exploring social work practice in diverse criminal justice settings in the northwestern United States, a subsample of 9 social workers described the difficulties they experience adhering to social work’s professional code of ethics. They identify 2 primary areas of divergence, conflicting responsibilities and opposing interests, and identify the ways they respond to these challenges and the rationale behind their decisions. The discussion section explores avenues for strengthening social workers’ abilities to be a vital and ethical presence in criminal justice settings.
Adversity Across the Life Course ofIncarcerated Parents: Gender Differences
Authors: Borja> Sharon , Nurius Paula , Eddy J. Mark
Published: January 2016

More than half of the 1.6 million adults in U.S. prisons are parents.Despite growing knowledge regarding the life course adversities ofcorrections-involved populations, less is known regarding incarcer-ated parents per se and the implications of cumulative adversitiesboth on their needs and those of their children. Using agender-balanced (41%minority) sample of incarcerated parents(N¼357) from a randomized controlled trial of an in-prisonparent training program, this study examines differences betweenincarcerated mothers and fathers in their exposures to adversitiesacross the life course. Mothers and fathers shared similar patternsof adversity exposure in their families of origin but differed in theirexperiences of juvenile justice and child welfare systems involve-ment, as well as in their adult experiences of victimization andrelated adult social and mental health outcomes. Implications forgender-responsive parent support and prevention programs for theirchildren of incarcerated mothers and fathers are discussed.
Death Penalty Attitudes of Social Work Students: Current and Future Opportunities
Authors: Kennedy Stephanie , Tripodi Stephen
Published: January 2016

Although much is known about the death penalty attitudes of U.S. adults, the attitudes of social workers are less clear. The current study assesses the death penalty attitudes of 406 social work students at a southern university. Support was measured in isolation, in conjunction with alternative sentencing structures, and using vignettes to provide mitigating factors about the defendant and the crime. Social work students reported low levels of death penalty support (32%), which decreased when alternative sentences were provided (11%). Death penalty support was lowest on case vignettes (range: 0–16%). Implications for social work and future research directions are discussed.
The Potential Costs of Police Databases: Exploring the Performance of California’s Gang Database (CalGang)
Authors: Petering Robin
Published: January 2016

Informatics and databases used to track crime are an increasing part of crime prevention strategies and hold promise for identifying individuals likely to be involved in crime so they can be more easily tracked to prevent future crimes. This article uses cost analysis techniques to explore the utility of California’s gang prevention database (CalGang) from 1997 to 2010. Costs included the primary operating costs of the database and secondary costs associated with Type I and Type II errors. CalGang tracks more than 235,000 individuals implicated in gang activity statewide. Although the primary costs of operating the database were relatively low, secondary costs resulting from errors were much larger and led to an overall greater cost to society. In addition, it appears that CalGang has not been successful in reducing the rate of gang-related crime in Los Angeles. Resources for CalGang may be better spent on other crime prevention activities that are less costly to society and lead to greater prevention.
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a
Authors: Shields Benjamin J. , Jackson Jacob T. , Metcalf Donald , Shi Wei , Huang Qiutong , Garnham Alexandra L. , Glaser Stefan P. , Beck Dominik , Pimanda John E. , Bogue Clifford W. , Smyth Gordon K. , Alexander Warren S. , McCormack Matthew P.
Published: January 2016

Unlike clustered HOX genes, the role of nonclustered homeobox gene family members in hematopoiesis and leukemogenesis has not been extensively studied. Here we found that the hematopoietically expressed homeobox gene Hhex is overexpressed in acute myeloid leukemia (AML) and is essential for the initiation and propagation of MLL-ENL-induced AML but dispensable for normal myelopoiesis, indicating a specific requirement for Hhex for leukemic growth. Loss of Hhex leads to expression of the Cdkn2a-encoded tumor suppressors p16INK4a and p19ARF, which are required for growth arrest and myeloid differentiation following Hhex deletion. Mechanistically, we show that Hhex binds to the Cdkn2a locus and directly interacts with the Polycomb-repressive complex 2 (PRC2) to enable H3K27me3-mediated epigenetic repression. Thus, Hhex is a potential therapeutic target that is specifically required for AML stem cells to repress tumor suppressor pathways and enable continued self-renewal.
P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
Authors: Sansó Miriam , Levin Rebecca S. , Lipp Jesse J. , Wang Vivien Ya-Fan , Greifenberg Ann Katrin , Quezada Elizabeth M. , Ali Akbar , Ghosh Animesh , Larochelle Stéphane , Rana Tariq M. , Geyer Matthias , Tong Liang , Shokat Kevan M. , Fisher Robert P.
Published: January 2016

The transcription cycle of RNA polymerase II (Pol II) is regulated at discrete transition points by cyclin-dependent kinases (CDKs). Positive transcription elongation factor b (P-TEFb), a complex of Cdk9 and cyclin T1, promotes release of paused Pol II into elongation, but the precise mechanisms and targets of Cdk9 action remain largely unknown. Here, by a chemical genetic strategy, we identified ∼100 putative substrates of human P-TEFb, which were enriched for proteins implicated in transcription and RNA catabolism. Among the RNA processing factors phosphorylated by Cdk9 was the 5′-to-3′ “torpedo” exoribonuclease Xrn2, required in transcription termination by Pol II, which we validated as a bona fide P-TEFb substrate in vivo and in vitro. Phosphorylation by Cdk9 or phosphomimetic substitution of its target residue, Thr439, enhanced enzymatic activity of Xrn2 on synthetic substrates in vitro. Conversely, inhibition or depletion of Cdk9 or mutation of Xrn2-Thr439 to a nonphosphorylatable Ala residue caused phenotypes consistent with inefficient termination in human cells: impaired Xrn2 chromatin localization and increased readthrough transcription of endogenous genes. Therefore, in addition to its role in elongation, P-TEFb regulates termination by promoting chromatin recruitment and activation of a cotranscriptional RNA processing enzyme, Xrn2.
Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity
Authors: Luo Zhuojuan , Lin Chengqi , Woodfin Ashley R. , Bartom Elizabeth T. , Gao Xin , Smith Edwin R. , Shilatifard Ali
Published: January 2016

Genomic imprinting is a critical developmental process characteristic of parent of origin-specific gene expression. It is well accepted that differentially DNA-methylated regions (DMRs) and enhancers are two major classes of cis-elements determining parent of origin-specific gene expression, with each recruiting different sets of transcription factors. Previously, we identified the AF4/FMR2 (AFF) family protein AFF3 within the transcription elongation complex SEC-L3. Here, we report that AFF3 can specifically bind both gametic DMRs (gDMRs) and enhancers within imprinted loci in an allele-specific manner. We identify the molecular regulators involved in the recruitment of AFF3 to gDMRs and provide mechanistic insight into the requirement of AFF3 at an enhancer for the expression of an ∼200-kb polycistronic transcript within the imprinted Dlk1-Dio3 locus. Our data suggest that the heterochromatic environment at the gDMR reinforces silencing of its related enhancer by controlling the binding and activity of AFF3 in an allele-specific manner. In summary, this study provides molecular details about the regulation of dosage-critical imprinted gene expression through the regulated binding of the transcription elongation factor AFF3 between a DMR and an enhancer.
CRISPR Technology for Genome Activation and Repression in Mammalian Cells
Authors: Du Dan , Qi Lei S.
Published: January 2016

Targeted modulation of transcription is necessary for understanding complex gene networks and has great potential for medical and industrial applications. CRISPR is emerging as a powerful system for targeted genome activation and repression, in addition to its use in genome editing. This protocol describes how to design, construct, and experimentally validate the function of sequence-specific single guide RNAs (sgRNAs) for sequence-specific repression (CRISPRi) or activation (CRISPRa) of transcription in mammalian cells. In this technology, the CRISPR-associated protein Cas9 is catalytically deactivated (dCas9) to provide a general platform for RNA-guided DNA targeting of any locus in the genome. Fusion of dCas9 to effector domains with distinct regulatory functions enables stable and efficient transcriptional repression or activation in mammalian cells. Delivery of multiple sgRNAs further enables activation or repression of multiple genes. By using scaffold RNAs (scRNAs), different effectors can be recruited to different genes for simultaneous activation of some and repression of others. The CRISPRi and CRISPRa methods provide powerful tools for sequence-specific control of gene expression on a genome-wide scale to aid understanding gene functions and for engineering genetic regulatory systems.