bluuebunny/crossref_metadata_2025 huggingface dataset:
Flash-Explosion: una tecnología innovadora para la obtención de puré de fruta de alta calidad
Authors: Rodríguez Fonseca Pablo Emilio , Vaillant Barka Fabrice , Arias Claudia Janeth , Ortega Villalba Karen Johana , Madroñero Solarte Inés Amelia , Soto Vega Iris Leidy
Published: April 2022

Flash-Explosion es un proceso térmico acoplado a una despulpadora que trabaja con presión al vacío y un sistema de envasado aséptico. El proceso Flash-Explosion permite la obtención de puré o pulpa de fruta de alta calidad en un solo paso. Esto quiere decir que esta tecnología integra diversas operaciones para obtener un puré de fruta libre de microorganismos patógenos, al tiempo que se conservan las propiedades de color, sabor y olor, así como los compuestos de las frutas asociados a beneficios de salud para el consumidor.
Content Analysis of Mobile Apps for Child Development Support (Preprint)
Authors: Dewitt Akeiylah , Kientz Julie , Liljenquist Kendra
Published: April 2022

UNSTRUCTURED

Following increases in smartphone access, more parents seek out parenting advice through internet sources, including blogs, online forums, or mobile applications (apps). However, searching and filtering through apps in the app store can be challenging due to lack of regulation in the quality of available mobile apps, especially among apps that share medical advice or track health behaviors. To understand the availability and quality of apps for early childhood health promotion, we completed a content analysis of apps in two major app stores (Google Play Store and Apple App Store). We found that most apps do not provide tailored experiences to parents, including cultural considerations and language diversity, and instead promote generic guidance that may be useful to parents in some contexts. We discuss the need for an evaluative framework to assess apps aimed to support parents on child development topics. Future work is needed that addresses accessibility of mobile apps in this area, and how health equity may be applied to evaluation and app development in this space.
A cognitive approach to review Ontological phenomenon and its existence in the domain of romance
Authors: Bandyopadhyay Dr. Sahadev
Published: April 2022

The branch of metaphysics dealing with the nature of being, a complete supernaturalfield of Philosophy is Ontology. I shall be lawful during the presentation of my arguments which I do believe. I believe present world needs to apply its thought in a positive way and that will give birth to ‘being’. This will accelerate our well-being to achieve our aims, aims for the better world – a new oxy-world. Romance and love may merge inside the soul to touch the first morning Sun for a new tomorrow.
THE PROPERTIES OF HIGH REDSHIFT GALAXIES
Authors: García L. A.
Published: April 2022

This work studies the connection between the first galaxies and their hosting dark matter halos in the early Universe when reionization is concluding. Our numerical models (already presented in an earlier study) trace the star formation history at z = 4 - 8, the galaxy stellar mass function, the stellar-to-halo mass distribution, and other high redshift galaxies statistics. All these predictions are consistent with observations to date and with other high-resolution cosmological simulations. A key finding of this work is the robust estimate of the cosmic star formation history (through the implementation of galaxy and supernova winds and atomic and molecular cooling processes) and self-consistent chemical pollution of the intergalactic medium. The theoretical models are compatible with a faint-end slope of the galaxy luminosity function of α = −2 at the end of reionization.
Analisis Pengaruh Dana Desa Terhadap Pembangunan Infrastruktur di Kecamatan Nglegok Kabupaten Blitar
Authors: Supriadi Verren Elyviana , Soelistyo Aris , Syaifullah Yunan
Published: April 2022

The purpose of this study is to determine the effect of Village Funds, Capital Expenditures, and Population Amounts for Infrastructure Development in Nglegok District in 2015-2019. This type of research is quantitative descriptive. The type of data used is secondary data obtained from the Office of Community and Village Empowerment (DPMD) in the form of financial statements of the Village Budget (APBDes).Census technique is used to determine the population in this population in this study. The sample of this research is 10 villages in Nglegok District.The data collection technique used is the documentation method. The technical analysis used is panel data regression. The results of this study suggested that the Village Fund variable has a significant positive effect on infrastructure development, the Capital Expenditure variable has a significant positive effect on infrastructure development, and the population has a significant negative effect on infrastructure development in Nglegok District.
Analisis Penawaran Ekspor Minyak Bumi Mentah Indonesia Pada Pasar Global Tahun 2009-2018
Authors: Yazid Fahrizal , Soelistyo Aris , Kusuma Hendra
Published: April 2022

The research objective is to determine the effect of the exchange rate, domestic and global inflation, GDP of each country, the export of crude oil in the previous year on Indonesia's crude oil exports. The number of samples used was 7 countries with a purposive sampling method. The method used is a quantitative method using secondary data obtained from the World Bank, Central Statistics Agency, Bank Indonesia. The analytical tool used is panel data regression. The results of this study indicate that the exchange rate, domestic inflation, crude oil exports in the previous year had a significant positive effect on Indonesia's crude oil exports and inflation to the destination country had a significant negative effect on Indonesia's crude oil exports, while the GDP did not have a significant positive effect on exports Indonesian crude oil.
ANALISIS PENYERAPAN TENAGA KERJA PADA INDUSTRI MANUFAKTUR BESAR DAN SEDANG PADA TINGKAT KABUPATEN/KOTA DI PROVINSI JAWA TIMUR (2017-2019)
Authors: Rosyana Novi , Soelistyo Aris
Published: April 2022

The study is intended to determine the analysis of the absorption of workers working in the industry of manufacturing large and medium at the level of districts / cities diprovinsi Java East in 2017-2019 . Expansion absorption of energy work is very necessary to keep pace with the rate of growth of the population , with the construction sector of the industry especially industrial manufacturing is expected to absorb over many workers work . The variable that is used is the number of industries , the value of production , and wage minimum using analysis regression multiple is regression panel data with 38 sample districts / cities in the province of Java east , the results of the study showed that the results of a number of industries , the value of production has a relationship that is positive and signinifikan , and wage minimum impact negatively not significant .
Analisis Faktor Yang Mempengaruhi Produk Domestik Regional Bruto Di Provinsi Jawa Barat Tahun 2015-2019
Authors: Agustina Suci , Hadi Syamsul
Published: April 2022

This study aims to determine the effect of Regional Original Income, Manpower, Domestic Investment, and General Allocation Funds on the Gross Regional Domestic Product of Regencies/Cities in West Java Province for 2015-2019. The researcher used a sampling technique with the Non-Regency Method in this study. Probability Sampling using Purposive Sampling, totaling 18 districts and nine cities. This study uses panel data. In this study, the fixed effect method is the best model. The results of this study are Regional Original Income and General Allocation Funds have a positive effect on the Gross Regional Domestic Product of districts/cities in West Java Province. In contrast, Domestic Workforce and Investment have a negative and significant impact on the Gross Regional Domestic Product of Regencies/Cities in West Java Province.
ANALISIS SUMBER - SUMBER PENDAPATAN ASLI DAERAH DI KOTA BLITAR
Authors: Hanafi Alfian Miftaqul , Riyanto Wahyu Hidayat , Kusuma Hendra
Published: April 2022

This research aims to find out how much the contribution and how effective the sources of Local Indigenous Income are to the Local Indigenous Income (PAD) of Blitar City. With the type of data used is secondary data obtained from the Office of Financial Management Revenue and Regional Assets of Blitar City and quantitative analysis tools in the form of calculation of the contribution of PAD sources, the ratio of effectiveness from PAD sources to PAD to know the financial independence of the region. The result is that the sources of Local Indigenous Income that contribute the most to PAD receipts are local taxes, while the lowest are the results of segregated management. When viewed from the effectiveness of PAD based on the calculation results obtained that the effectiveness of The Original Income of Blitar City Area is very effective with a value of 109.49%. As for the receipt of pad resources to know the financial independence of Blitar City area is still lacking with the average yield value – averaged over the last five years of 17.54%.
ANALISIS PENYERAPAN TENAGA KERJA PADA INDUSTRI GENTENG DI KECAMATAN GANDUSARI KABUPATEN TRENGGALEK
Authors: Ayuningtiyas Lely Diyah , Abdullah Mohammad Faisal , Suliswanto Muhammad Sri Wahyudi
Published: April 2022

The purpose of this study is to examine the influence of the number of industries, labor wages, and the amount of production toward the employment in tile industry in Gandusari, Trenggalek. The method of this study is quantitative research method with a statistical data retrieval using some calculations and hypothesis testing. Sampling using a cluster sampling technique. The classical assumption test, multiple linear regression analysis, and the regression coefficient significance test were carried out as the data analysis technique. The result of the partial model test reveal that the number of industries had a significant impact on the employment. Meanwhile, the labor wages indicate a negative significance impact on the employment. The amount of the production has a significant impact on the employment in tile industry. The simultaneous model testing reveals that the number of industries, labor wages as well as the amount of production have really significant effect on the employment.
Analisis Tingkat Kesejahteraan Buruh Nelayan di Kecamatan Bantur Kabupaten Malang
Authors: Andriani Iik WIdya , Nuraini Ida
Published: April 2022

This study aims to Know the Fishermen Welfare Level in Bantur District, Malang Regency. This research was conducted in Bantur District, Malang Regency. The population in this study were fishermen who were in Bantur District, Malang Regency, especially labor fishermen. The sample in this study was 30 families, especially labor fishermen. Data collection techniques used were questionnaires. The data analysis technique used is descriptive qualitative analysis. The results showed the level of welfare of fishermen measured using the Fisherman Exchange Rate (NTN) of labor fishermen in Bantur District, Malang Regency which was 154 where > 100, it can be said that all respondents were prosperous. Fishermen Exchange Rates are fluctuating, where the size is greatly influenced by the season, the lack of electricity supply, bad weather conditions and the scarcity of fuel supplied to fishing vessels. including fishing gear that has expired.
DETERMINAN KOMPONEN INDEKS PEMBANGUNAN MANUSIA DI KABUPATEN KEPULAUAN MADURA 2010-2017
Authors: Anggita Dian , Riyanto Wahyu Hidayat
Published: April 2022

The human development index is one of the measuring tools used to assess the quality of human development in an area by looking at the effects of physical conditions in the form of welfare and health and non-physical, namely education. The purpose of this study is to analyze mean years school (MYS) and per capita expenditure on the human development index in Madura Islands district from 2010 to 2017. The data used in this study is a secondary data obtained from Badan Pusat Statistik using the methods of data collection that is used is the study of documenting. The analytical tool used in this study is the panel data multiple regression method with the Fixed Effect Model (FEM).  The results showed that the variable mean years school (MYS) and per capita expenditure  had a positive and significant effect on the human development index in Madura Islands district. Variable mean years school (MYS) has a greater effect on the human development index in the madura islands district than the variable per capita expenditure.The human development index is one of the measuring tools used to assess the quality of human development in an area by looking at the effects of physical conditions in the form of welfare and health and non-physical, namely education. The purpose of this study is to analyze mean years school (MYS) and per capita expenditure on the human development index in Madura Islands district from 2010 to 2017. The data used in this study is a secondary data obtained from Badan Pusat Statistik using the methods of data collection that is used is the study of documenting. The analytical tool used in this study is the panel data multiple regression method with the Fixed Effect Model (FEM).  The results showed that the variable mean years school (MYS) and per capita expenditure  had a positive and significant effect on the human development index in Madura Islands district. Variable mean years school (MYS) has a greater effect on the human development index in the madura islands district than the variable per capita expenditure.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEMISKINAN DI WILAYAH TAPAL KUDA TAHUN 2012-2018
Authors: Hidayatullah Annasrul , Arifin Zainal , Suliswanto Muhammad Sri Wahyudi
Published: April 2022

The  purpose of this study was to analyze the effect of Gross Domesticl Product (GDP), Human Development Index (HDI) and Minimum Wages on poverty in the Tapal Kuda area. The regression analysis used in this study is panel data with the model used is Fixed Effect. In this study using quantitative types and types of secondary data obtained from the publication of the Central Bureau of Statistics. The results showed that the variables of GDP and HDI had a negative and significant effect on poverty. While the minimum wage variable has a positive and significant effect on poverty in the Tapal Kuda area.
In-silico Absorption, Distribution, Metabolism, Elimination and Toxicity profile of 9,12,15-Octadecatrienoic acid (ODA) from Moringa oleifera
Authors: Parvathi K. , Kandeepan C. , Sabitha M. , Senthilkumar N. , Ramya S. , Boopathi NM. , Ramanathan L. , Jayakumararaj R.
Published: April 2022

9,12,15-Octadecatrienoic acid (ODA) a carboxylic acid composed of 18 carbon atoms and three cis double bonds. ODA is a plant derived essential fatty acid indispensable to the human system. ODA refers to many different structural and conformational isomers, that differ in the position of the double bonds along the backbone and on whether they are in cis ('Z') or trans ('E') conformation. It has been well established that ODA can only be outsourced from food and then converted into eicosa-pentaenoic acid (EPA) and docosa-hexaenoic acid (DHA) in the human system. However, this metabolic process is highly limited and the rate of conversion is influenced by several factors such as dose, gender, and disease. Studies suggest that ODA is associated with reduced risk of fatal ischemic heart disease. Further, higher intake may reduce the risk of sudden death among prevalent myocardial infarction in patients consistent with induced antiarrhythmic effect. ODA significantly reduces blood clots. Traditional usage of ODA is attributed to its cardiovascular-protective, anti-cancer, neuro-protective, anti-osteoporotic, anti-inflammatory, and anti-oxidative properties. Recent pharmacological indicate that ODA has anti-metabolic syndrome, anticancer, anti-inflammatory, anti-oxidant, anti-obesity, neuro-protective, and more specifically involved in the regulation of gut-micro-floral functionalities. Studies, both experimental and clinical trials indicate that ODA has anti-metabolic syndrome effects. In short, ODA is potentially used to treat many diseases, but in-depth ADMET studies are required to firmly re-establish its clinical efficacy and market potential.

Keywords: ADMET; Moringa oleifera; Secondary Metabolites; Natural Products (NPs); Bioactive Substances; Octadecatrienoic acid (ODA); Eicosa-Pentaenoic Acid (EPA); Docosa-Hexaenoic Acid (DHA)
Oxygen, Hyperbaric Oxygen and Ozone as Therapeutic Agents in Oral and Maxillofacial Surgery: literature Review
Authors: Eltahir Manal Abdalla
Published: April 2022

Medical consideration in the surgical specialities such as Oral and Maxillofacial Surgery, in the form of prescribing medications for some diseases, preoperative preparation, post operative care and follow up, is an important and integrated part in management of surgical patients,

Oxygen as the drug plays key role in treatment of surgical patient, and contributes strongly in treatment of major trauma, shock, sepsis; perioperative and postoperative considerations and in patients with various other medical comorbidities.

 in this review we discussed the oxygen therapy as well as hyperbaric Oxygen in addition to the Oxygen with the 3 atoms, namely Ozone, in oral and Maxillofacial Surgery speciality.

Keywords: O2 supplement, adjunctive therapy, HBO, OZONE, osteonecrosis, Medication related necrosis
Phenytoin Induced Drug Rash with Eosinophilia and Systemic Symptoms: A rare paediatric case report
Authors: Pattanshetti Aishwarya , Bali Prasad N.
Published: April 2022

Purpose: Dress Syndrome (Drug rash with eosinophilia and systemic symptoms) is a severe adverse drug reaction characterised by rash, fever, lymphadenopathy, and organ involvement. It is a severe, one-of-a-kind adverse medication reaction. DRESS is the most rarely seen severe adverse drug reaction, and it affects approximately 1 in a thousand to 1 in a ten thousand patients who take the drug. It is found that the mortality rate is nearly 10 %. The main objectives include - learn the importance of DRESS syndrome, recognize the signs and symptoms of DRESS, to know what diagnostic studies are indicated and to provide accurate treatment.

Methods: The case of 11-year-old girl who came with history of head injury and was given phenytoin to treat it. Later she came with a complaint of numerous urticated papules and plaques on her trunk, neck, both upper and lower limbs, and febrile since 4days. And we used the Regi SCAR scoring system that grades DRESS cases as ‘no’, ‘possible’, ‘probable’ or ‘definite’ groups for diagnostic criteria of DRESS. And we also applied Naranjo’s causality assessment scale in the following case study.

Results and conclusion: In the initial recognition of DRESS syndrome and the immediate withdrawal of offending drugs and continuing with a supportive therapy and corticosteroids as needed. Systemic corticosteroids can reduce symptoms of hypersensitivity reactions.

Keywords: Drug Reaction with Eosinophilia and Systemic Symptoms, Phenytoin, Exfoliation of Skin, Corticosteroids.
A Short Review of New Drugs for Heart Failure: Omecamtiv Mecarbil and Vericiguat
Authors: Laksono Sidhi , Pratama Ahmad Pandu , Halomoan Reynaldo , Andra Cut Aryfa
Published: April 2022

Heart failure is associated with increased morbidity and mortality. Although developments of therapeutic agents have shown benefit and have improved the patients’ condition, there is only a slight decreased of mortality rate throughout the years. This condition becomes a reason to develop efficient drugs which can further improve the condition and reducing the mortality significantly. New therapeutic agents have been proposed and studied. Among them is cardiac myosin activator, such as omecamtiv mecarbil. This drug will increase the binding of myosin head to the actin and therefore form a stronger contraction. Omecamtiv mecarbil is beneficial due to its mechanism which not related to higher oxygen consumption and less adverse events. Another promising drug is vericiguat, a soluble guanylate cyclase (sGC) stimulator. This drug enhances the binding of nitric oxide to sGC and therefore increasing cyclic guanosine monophosphate (cGMP) production. cGMP important in regulating physiological processed in the cardiovascular system. In this review, we will discuss about the current evidence about these novel agents.

Keywords: heart failure, novel agent, omecamtiv mecarbil, vericiguat, management
Street Literacy as an Effort to Improve Healthy Behavior of Street Teenagers: Is it effective?
Authors: Chairani Reni , Palestin Bondan , Netty Elya
Published: April 2022

Background: Street teenagers are one of the groups vulnerable to health problems. It is evident from basic health research that smoking behavior has started since the age of 10 years, with 13.4% of adolescents having used cigarettes regularly every day and 9.63% of adolescents already familiar with alcohol. Street teenagers with all their limitations are required to help the family's economy and must be willing to share time between work and study or play in accordance with their developmental tasks. If this is allowed, then Indonesia will lose so many potential young generations in the future. Street literacy by providing reading sources about health for street teenagers and mentoring is expected to increase the enthusiasm of street teenagers to care about their health, so that the adaptive behavior of teenagers can increase. Objective: This study aims to analyze the effectiveness of street literacy on increasing healthy behavior in an effort to prevent the health problems of street teenagers. Methods: This research is a quasi-experimental with a pretest and posttest with one group design. The research was conducted by implementing street literacy activities for three months starting July-September 2021. The sample of this research was 60 street teenagers, from the Akur Kurnia halfway house in Jakarta and the Ahmad Dahlan halfway house in Yogyakarta. The research variable is the independent variable: street literacy which is oriented to cognitive and behavioral development, while the dependent variable is the behavior of street teenagers towards preventing teenager health problems which includes knowledge, attitudes, and skills or actions of street youth towards health prevention. Data analysis in this study used the paired sample test. Result: the application of street literacy can increase the knowledge (p=0.000), attitudes (p=0.000) and skills (p=0.000) of street teenagers in health prevention. Conclusion: street literacy is effective in improving the health behavior of street teenagers.

Keywords: Street literacy, street teenagers, health behavior
Complex-Information Ethics Theory
Authors: Solis Ken
Published: April 2022

If ethics is of any interest to big historians, it might be primarily for analyzing the “ought to haves” and the “ought not to haves” of prior large scale human actions, e.g., does an agriculture-based lifestyle cause more harms to humans overall as compared with a hunter-gatherer lifestyle? However, big historians are also often concerned about the future events of Earth that can be influenced by humans, such as climate change, mass extinctions, and the predicted technological singularity. Because those concerns encompass both human and non-human complex systems such as the biosphere and possible future advanced artificial intelligence, big history requires an ethical framework that addresses anthropocentric as well as non-anthropocentric concerns and perspectives.
Efektivitas Penggunaan Macromedia Flash pada Perkuliahan Jarak Jauh Sistematika Tumbuhan Rendah Pendidikan Biologi FKIP Universitas Riau Tahun 2021
Authors: Sayuti Irda , Mahadi Imam , Darmawati Darmawati , Nursal Nursal , Harlis Harlis
Published: April 2022

The purpose of this study was to determine the effectiveness of using macromedia flash in the distance lectures for students of the Biology Education Study Program, FKIP University of Riau in 2021. This media application was applied to learning low-level plant systematics (STR) courses. The research was conducted at the Biology Education Study Program, FKIP Riau University, in the even semester of 2021. The object of the research was 35 students of Class A lectures on low-level plant systematics. The research was conducted using the classroom action method, namely applying macromedia flash learning media. The lecture period is divided into 2 rounds where the first round is learning without using macromedia flash media and the second round using macromedia flash. The indicators set in the form of student learning outcomes during lectures and student responses to the use of macromedia flash. The conclusion of the study is that the use of macromedia flash can improve student learning outcomes with an effectiveness ratio of 83% and is considered effective in terms of learning outcomes. Student responses to the application of macromedia flash media are classified as good with a percentage of 79.91%.
Key words: Macromedia flash, Low Plant Systematics, Effectiveness
 
Abstrak. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas Penggunaan macromedia flash pada perkuliahan jarak jauh mahasiswa Program Studi Pendidikan biologi FKIP Univeristas Riau tahun 2021. Aplikasi media ini diterapkan pada pembelajaran mata kuliah sistematika tumbuhan tingkat rendah (STR). Penelitian dilakukan di program studi pendidikan biologi FKIP Universitas Riau pada semester genap tahun 2021. Objek penelitian adalah mahasiswa Kelas A oerkuliahan sistematika tumbuhan tingkat rendah sebanyak 35 orang. Penelitian dilakukan dengan metode tindakan kelas yaitu menerapkan media pembelajaran macromedia flash. Masa perkuliahan dibagi dalam 2 putaran dimana putaran pertama adalah pembelajaran tanpa penggunaan media macromedia flash dan putaran kedua dengan menggunakan macromedia flash. Indikator yang ditetapkan berupa hasil belajar mahasiswa selama perkuliahan serta respon mahasiswa terhadap penggunaan macromedia flash.. Kesimpulan dari Penelitian diketahui  bahwa penggunaan macromedia flash dapat meningkatkan hasil belajar mahasiswa dengan rasio efektivitas 83% dan tergolong efektif dari segi hasil pembelajaran. Respon mahasiswa terhadap penerapan media macromedia flash tergolong baik dengan presentase 79.91%.
Kata kunci: Macromedia flash, Sistematika Tumbuhan Rendah, Efektivitas
TD-DFT Modeling of Electronic Spectra of Biliverdins in Different Environments
Authors: Mirón Gonzalo Diaz , Estrin Dar"o A. , Bari Sara , Lebrero Mariano González
Published: April 2022

Non covalent biliproteins are found in a growing number of living
organisms and even in viruses, such as SARS-CoV-2. Unlike the well
described covalent biliproteins, such as the phytochromes, they present
a vast structural and functional diversity, and often with limited
experimental information. A very important tool (and sometimes the only
one available) to study these systems is the UV-Vis spectrum, which is
modulated both by conformational changes of the biliverdin chromophore
and specific interactions with the apoprotein. In this work we present a
theoretical study of the microscopic determinants of the UV-Vis spectrum
of these compounds through the use of hybrid QM(TD-DFT)/MM techniques
and molecular dynamics simulations. Comparing our results with existing
experimental data, we prove that it is possible to predict spectroscopic
properties, such as relative position and intensity ratio of main bands,
with affordable methods, and to provide a microscopic explanation of
them. This systematic information can be very useful for the study of
described biliproteins or for those yet unknown.
Non-relativistic limit of the Euler-HMPN approximation model arising in radiation hydrodynamics
Authors: Ma Zhiting , Yong Wen-An
Published: April 2022

In this paper, we are concerned with the non-relativistic limit of a
class of computable approximation models for radiation hydrodynamics.
The models consist of the compressible Euler equations coupled with
moment closure approximations to the radiative transfer equation. They
are first-order partial differential equations with source terms. As
hyperbolic relaxation systems, they are showed to satisfy the structural
stability condition proposed by W.-A. Yong (1999). Base on this, we
verify the non-relativistic limit by combining an energy method with a
formal asymptotic analysis.
New Year’s Silent Killer in Japan: Undigested Mochi
Authors: Kawanishi Koki , Ikeda Yoshifumi
Published: April 2022

We report the case of a 65-year-old woman who presented to our hospital
with a complaint of abdominal pain due to undigested mochi, which was
resolved by snare cutting.
Hypertrophic Cardiomyopathy secondary to Tacrolimus in a kidney transplant patient: A case report and focused review of the literature
Authors: Silva Guillermo Hernández , Chaparro Ricardo Giovanni Puerto , Melo Javier Álvaro Martínez , Bueno Cristian Orlando Porras , Rodríguez Javier Eduardo Martínez , Trillos Sharon Julieth González
Published: April 2022

In receptors of solid organ transplant, calcineurin inhibitors has
become a pillar of immunosuppressive treatment. Several case reports
have shown hypertrophic and dilated cardiomyopathy as a side effect of
tacrolimus. We present the case of a woman receptor of a kidney
transplant who developed hypertrophic cardiomyopathy due to Tacrolimus.
Prediction of Urban Inundation Depths using a Machine Learning Model: An Application to Shenzhen, China
Authors: Sun Dianchen , Wang Huimin , Lall Upmanu , Huang Jing , Liu Gaofeng
Published: April 2022

Urban pluvial flooding caused by extreme rainfall has been increasing
globally, thus exacerbating loss of life and damage to property.
Accurate and updated real-time forecasts are critical needs for urban
flooding response and defense. Big data has opened new avenues for
inundation depth prediction in complex urban settings. In this study, a
new method for pluvial flood classification was proposed for an
inundation depth change index (IDCI) by dividing floods into three
types: pluvial persistent floods (PPFs), pluvial normal floods (PNFs)
and pluvial flash floods (PFFs). Prediction models are identified for
the three flood types using data from a network of sensors (109 rainfall
stations and 80 flood water depth stations) in Shenzhen, China. The
results show that backpropagation neural networks (BPNNs) and long
short-term memory (LSTM) exhibit good performance in depth prediction
but are not significantly different from one another. In addition, PPFs
require a longer rainfall sequence to obtain a better forecast. The
Nash-Sutcliffe efficiency (NSE) of the depth prediction results at all
stations is 0.86. The prospects for generalizing this approach and its
usage are discussed.
Postpartum home blood pressure monitoring and lifestyle intervention in the first year after a hypertensive disorder of pregnancy: A pilot feasibility trial
Authors: Hauspurg Alisse , Seely Ellen , Rich-Edwards Janet , Hayduchok Christina , Bryan Samantha , Roche Andrea , Jeyabalan Arun , Davis Esa , Hart Renee , Shirriel Jada , Catov Janet
Published: April 2022

Objective: To test the feasibility of a randomized trial of home blood
pressure monitoring paired with a remote lifestyle intervention vs. home
blood pressure monitoring alone vs. control in individuals with a
hypertensive disorder of pregnancy in the first year postpartum. Design:
Single-blinded randomized clinical trial Setting: Two tertiary hospitals
and a community organization Population: Overweight and obese
individuals with a hypertensive disorder of pregnancy and without
pre-pregnancy hypertension or diabetes. Methods: We assessed the
feasibility of recruitment and retention of 150 participants to study
completion at one-year postpartum with randomization 1:1:1 into each
arm. Secondary aims were to test effects of the interventions on weight,
blood pressure and self-efficacy. Results: Over 23 months, we enrolled
148 of 400 eligible, screened individuals (37%); 28% Black or Other
race, and mean pre-pregnancy BMI of 33.4±6.7 kg/m2. In total, 129 (87%)
participants completed the one-year postpartum study visit. Overall,
22% of participants developed stage 2 hypertension [≥140/90 mmHg or
on anti-hypertensive medications] by one-year postpartum. Individuals
in the lifestyle intervention arm had a greater, non-significant
decrease in mean arterial pressure (MAP) compared to individuals in the
HBPM alone and control arm [mean change in MAP (95%CI) -3.7(-6.5,
-0.9), -0.5(-1.5, 2.6), -1.0(-4.1, 2.2) mmHg], respectively. There
were no differences in weight or self-efficacy by study arms.
Conclusion: In this pilot, randomized trial, we demonstrate feasibility
of HBPM paired with a lifestyle intervention in the first year
postpartum. We detected high rates of ongoing hypertension emphasizing
the need for effective interventions in this population.
Ten-year Longitudinal Analysis of Hydroxyurea Implementation in a Pediatric Sickle Cell Program
Authors: Phan Vivian , Park Ju Ae , Dulman Robin , Lewis Angela , Briere Noravy , Notarangelo Bailey , Yang Elizabeth
Published: April 2022

Hydroxyurea (HU) has proven benefit in sickle cell anemia (SCA), but HU
is still underutilized. The Pediatric Sickle Cell Program of Northern
Virginia prescribes HU uniformly regardless of symptoms to SCA patients
age ≥ 9 months and prospectively tracks outcomes. HU is prescribed to
maximum tolerated dosing (MTD) to target 30% Hgb F. Longitudinal data
over 10 years from 2009-2019 were analyzed in 2-year intervals for
hemoglobin (Hgb), fetal hemoglobin (Hgb F), hospitalizations,
transfusions, and treat-and-release ED visits. Comparing the 2-year
interval prior to uniform HU implementation (2009-2011) to the last
2-year interval analyzed after HU implementation (2017-2019), HU usage
increased from 33% to 93%, average Hgb increased from 8.3±0.98 to
9.8±1.3 g/dL (p<0.0001), average Hgb F rose from 13±8.7% to
26±9.9% (p<0.0001), hospitalizations decreased from 0.71
(95% CI 0.54-0.91) to 0.2 (95% CI 0.13–0.28) admissions/person-year,
sporadic transfusions decreased from 0.4 (95% CI 0.27–0.55) to 0.05
(95% CI 0.02–0.12) transfusions/person-year. Treat-and-release ED
visit rates remained unchanged, varying between 0.49 (95% CI 0.36-0.64)
and 0.64 (95% CI 0.48-0.83) visits/person-year. By the last 2-year
interval, 72% of patients had Hgb ≥ 9g/dL, 42% had Hgb F ≥ 30%, 79%
experienced no hospitalizations, and 94% received no transfusions.
Prescription of HU uniformly for SCA patients to achieve high Hgb F
resulted in significant improvements in laboratory and clinical outcomes
within 2 years that continued to improve over the next 6 years. Rigorous
HU implementation uniformly in a pediatric sickle cell program is
feasible, effective, and sustainable.
Investigating possibilities for synthesis of novel sorbents and catalyst carriers based on ceramics with controlled open porosity
Authors: Nikolic Vesna , Djokic Jovana , Kamberovic Zeljko , Marinkovic Aleksandar , Jevtic Sanja , Andjic Zoran
Published: April 2022

The aim of this study was to investigate a possibility of synthesis of porous ceramics with controlled open porosity, which could be used as sorbents and catalyst supports. Two organic additives were used to obtain open porosity: polystyrene beads and cellulose fibers, which are mixed with kaolin clay powder and the appropriate water content. Samples were sintered at 1050?C for 1 h. Characterization of the obtained products included X-ray powder diffraction analysis (XRPD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and elemental CHNS analysis. In addition, porosity was examined by quantification of visual information. The specific surface areas were determined by the Brunauer?Emmett?Teller (BET) method. Also, density and compressive strength of the obtained samples were assessed. It was determined that by sintering, the organic component completely leaves the system. For samples prepared with polystyrene beads and with cellulose fibers, satisfactory mechanical properties were obtained: compressive strengths were 1.42 and 1.56 MPa, respectively. It was noted that significantly higher open porosity was obtained by using polystyrene beads as a sacrificial template (porosity of ~56 %) instead of cellulose fibers (porosity of ~6 %).
Serpent Intertexts: Tantalizing Twists in the Tales
Authors: PHILLIPS ELAINE A.
Published: April 2022

Intertextuality as an approach to biblical studies has received considerable attention and varied responses. Because the foundation of the enterprise is the almost limitless potential in interrelated texts, the complexity both of definition and of process is daunting. At the same time, the pursuit through this complexity yields a renewed appreciation for the richness of the biblical text in its wider cultural contexts. Tracking the serpent through the wealth of intertextual connections in the Hebrew Bible illustrates the ongoing infusion of ideas and development of interconnections. The approach does not presume the loss of the authoritative Center but acknowledges that divine Authorship does not preclude a plurality of voices as the canonical text is produced and interpreted.
Implications of Paul's "One Flesh" Concept for His Understanding of the Nature of Man
Authors: SON S. AARON
Published: April 2022

Closely related to his σῶμα concept, Paul's view of the sexual union as "one flesh (body)" has significant implications not only for his understanding of the nature of man but also of the relationship between Christ and the church. Paul derives this concept from Gen 2:24 and uses it as the biblical basis for his argument, explicitly in 1 Cor 6:12–20; Eph 5:21–33; and implicitly in 1 Cor 7:10–16. In this article, I examine these and other related passages to determine whether and in what respect Paul understands man as a corporate being.
Garnishing with the "Greater Righteousness": The Disciple's Relationship to the Law (Matthew 5:17–20)
Authors: CHARLES J. DARYL
Published: April 2022

As seen from the perspective of Matthew's Gospel, the nature of Christian discipleship requires self-attestation through good works and a conspicuous lifestyle. Hence it is necessary to underscore the importance of Christian ethics and the character of bona fide righteousness. The ethical tenor of much of the material in Matthew can be understood against the background of the Jewish-Christian community's becoming increasingly Gentile-Christian as well as the early church's relationship to first-century Judaism. What is striking is the degree to which the halakah advanced by Jesus himself appears to stand in continuity with the OT. The "greater righteousness" called for by Jesus does not stand in juxtaposition to the ethical standard enunciated in the law and the prophets. Rather, it is to be understood against the ethical deficiencies of contemporary establishment religion.
Patient Perception of the Diagnosis Announcement and its Impact on Quality of Life of Patients with Primary Melanoma or Basal Cell Carcinoma
Authors: Aymonier Marie , Taieb Charles , Corgibet Florence , Joly Pascal , Sei Jean-Francois , Chaussade Veronique , Philippe Caroline , Ezzedine Khaled , Richard Marie-Aleth
Published: April 2022

An improved understanding of the impact of skin cancer on patients’ daily life may optimize disease management. This questionnaire survey of adult patients in real-world settings aimed to assess patient perception of the diagnosis announcement, and the impact of the diagnosis on the patients’ professional and personal life. Data from 355 patients with melanoma and 320 patients with basal cell carcinoma (BCC) were analysed. Melanoma significantly impacted the couple, and sexual relationships, as well as family and social life, and reduced the patient’s libido more significantly than did BCC (all p < 0.05). Melanoma and BCC significantly impacted the patients’ professional and personal lives. The word “cancer” used for a BCC announcement has a high anxiety-producing meaning for the patient. The announcement of each skin cancer should be made during a dedicated consultation, with more time devoted to the patient and with specific empathy, in order to improve reassurance of the patient.
Selvitys kotimaisten tieteellisten julkaisujen toimitusten koulutus- ja yhteistyötoiveista
Authors: Mäkilä Annastiina
Published: April 2022

Selvitys pohjautuu keväällä 2021 toteutettuun kyselyyn. Selvityksen tavoitteena oli kartoittaa kotimaisten tiedelehtien tarpeita kirjoittajakoulutusten, verkostotapaamisten, toimittajakoulutuksen, julkaisemisen haasteiden tai muun tuen suhteen. Selvitys pyrki kattamaan kotimaiset tieteelliset julkaisut laajasti eri tieteenaloilta. Selvityksen pohjalta voidaan suunnitella koulutuksia ja myöhempää yhteistyötä.
TIKTOK AS A PERSPECTIVE CHANNEL PROMOTION FOR MEDIA
Authors:   Lviv Polytechnic National University, Iryna Mudra
Published: April 2022

The TikTok as a social network is gaining popularity very quickly. Two years ago, it was not taken seriously, it was considered as a platform for teenagers, where there is nothing but dancing and flash mobs. But now the situation has changed vice versa. TikTok is rapidly increasing its audience and content is also changing. Nowadays, not only musicians but also doctors, deputies, lawyers, advertisers, motorists, and representatives of other professions are actively maintaining and developing their accounts there. Accordingly, the attitude to this social network has also changed. Today it is no longer just an application with dances and songs, but a platform where you can easily, and originally present information, even boring and uninteresting, but so necessary and useful. The media also follows the rapid popularity of TikTok and changes in content. And where there is an audience, there are prospects for media promotion. Therefore, more and more media are coming to this application. But they do it in two ways. First: they adapt to the format of the platform, even serious media publish funny videos, use popular music and grimace at the camera. Second: they publish content that has already been posted on other social networks, ignore the TikTok format, also post excerpts from shows, news releases, so they often do not receive enough attention from the audience. After all, TikTok differs from other social networks, so the content that is suitable for Facebook, Instagram, YouTube, on this platform is not gaining views. After all, each social network has its own format of creating and submitting content, so each platform for communication must be made individual content. The media do not always follow this rule, so they are often disappointed in TikTok and do not develop their account in it. We have examined which Ukrainian mass media and how they distribute their content in TikTok. We found out whether this social network is promising for the promotion of the media and its products.
Text Mining for Employee Candidates Automatic Profiling Based on Application Documents
Authors: Wibawa Adhi Dharma , Amri Arni Muarifah , Mas Arbintoro , Iman Syahrul
Published: April 2022

Opening job vacancies using the Internet will receive many applications quickly. Manually filtering resumes takes a lot of time and incurs huge costs. In addition, this manual screening process tends to be inaccurate due to fatigue conditions and fails in obtaining the right candidate for the job. This paper proposed a solution to automatically generate the most suitable candidate from the application document. In this study, 126 application documents from a private company were used for the experiment. The documents consist of 41 documents for Human Resource and Development (HRD) staff, 42 documents for IT (Data Developer), and 43 documents for the Marketing position. Text Processing is implemented to extract relevant information such as skills, education, experiences from the unstructured resumes and summarize each application. A specific dictionary for each vacancy is generated based on terms used in each profession. Two methods are implemented and compared to match and score the application document, namely Document Vector and N-gram analysis. The highest the score obtained by one document, the highest the possibility of application to be accepted. The two methods’ results are then validated by the real selection process by the company. The highest accuracy was achieved by the N-Gram method in IT vacancy with 87,5%, while the Document Vector showed 75% accuracy. For Marketing staff vacancy, both methods achieved the same accuracy as 78%. In HRD staff vacancy, the N-Gram method showed 68%, while Document Vector showed 74%. In conclusion, overall the N-gram method showed slightly better accuracy compared to the Document Vector method.
Political Matters
Authors: Haghighi Farzaneh , Bobic Nikolina
Published: April 2022

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Peripheral territories: Imagining common worlds differently
Authors: Engels- Schwarzpaul A.-Chr.
Published: April 2022

At the beginning of spatial struggle is separation: perception of what is in, or outside of, one’s body, one’s house, kin, neighbourhood, and polity. We all have vague or even detailed ideas of that separation—but this we often goes unnoticed, the very notion that performs the very separation we imagine. For instance, we tend to associate a territory with a nation-state and a homogenous population, while a periphery appears to lack connection and substance. Marking territory along these associations is challenging after forty years of global neoliberal politics, resulting in the displacement of millions of people and austere biopolitical measures. Against this backdrop, this paper explores the politics of place and mobility, exemplified by two case studies, one in the Mediterranean and the other in the Pacific, to raise an urgent contemporary question: how can we negotiate between the freedom of movement, on the one hand, and the protection of Indigenous land rights and self-determination, on the other?
Epidemiological characteristics of varicella outbreaks in the Republic of Korea, 2016–2020
Authors: Kim Eun-Young , Park Chungmin , Lee Gyehee , Jeong Suyeon , Song Jeongsuk , Lee Dong-Han
Published: April 2022

Objectives: We described the trends and epidemiological characteristics of varicella outbreaks from 2016 to 2020 in the Republic of Korea.Methods: We investigated variables such as the outbreak setting, age of patients, vaccination status, and lesion count. The collected data were analyzed with the Cochrane-Armitage trend test and Kruskal-Wallis test. These statistical tests were performed using R ver. 4.0.3.Results: The number of varicella outbreaks increased from 2016 to 2018; however, after a slight decrease in the number of outbreaks in 2019, the number fell sharply in 2020. The median size of outbreaks decreased from 8 to 9 cases during 2016−2019 to 6 cases in 2020. The median duration of outbreaks was 18 days during 2016−2017, 28 days in 2018, 29 days in 2019, and 15 days in 2020. Varicella outbreaks occurred most frequently in elementary schools, and vaccination coverage of patients increased from 89.4% in 2016 to 97.2% in 2019. The median age of patients with outbreak-related varicella decreased from 8 years in 2016 to 6 years in 2020.Conclusion: Significant changes were observed in the age of patients with outbreak-related varicella. Ongoing monitoring of varicella outbreaks should be conducted. Further research will be needed to measure the disease burden of varicella and enable evidence-based policy decisions.
Violencia epistémica en la formación musical
Authors: Burcet María Inés
Published: April 2022

Este trabajo describe un recorrido que resulta habitual cuando se aborda el contenido representación de la altura. Este constituye un ejemplo de tantos otros que circulan en la educación audioperceptiva, donde, a partir de supuestos indiscutidos que se sustentan en la teoría de la música, se replican estrategias de enseñanza que resultan autoritarias en cuanto se imponen como verdades únicas y reprimen otros modos de representar, escuchar, relacionar, en definitiva, de pensar y construir conocimiento.
¡Humanos al ataque!
Authors: Garro Pablo , Pretti Patricio
Published: April 2022

En Sonidos de Marte, David Stubbs narra una historia de la música electrónica desde una perspectiva personal, vinculando prácticas, artistas, técnicos/as y producciones para tejer una trama que se extiende por más de un siglo hasta nuestros días.