bluuebunny/crossref_metadata_2025 huggingface dataset:
Penyuluhan Asal Mula Teknologi Vaksin Bagi Millinneal Pasca Covid-19 Di Minggu Raya
Authors: Susilo Tanto Budi , Yunus Rahmat , Sanjaya Rahmad Eko , Soesanto Oni , Akbar Arief Rahmad Maulana , Hidayat Yuyun
Published: March 2024

AbstrakTulisan ini adalah bimbingan teknis akademis (bimteks) terhadap mahasiswa pasca covid-19. Suatu tinjauan ulang cognitive epistomology tentang vaksin yang digunakan. Ringkasan ulasannya berikut ini; Setelah perkembangan ilmu pengetahuan mikroorganisme pada era kisaran akhir abad 19, Griffith mengobservasi transformasi sel mikroorganisme streptococcus pheunomiae yang bersifat non patogen berubah menjadi patogen dengan metode thermal theraphy. Fenomena ini adalah mengesankan (impressive). Menjadi pertanyaan besar (enigma) mengapa kemampuan phatogensitas sel S. pheunomiae dapat berubah? Kesimpulan dapat ditarik telah terjadi transformasi akibat “sesuatu” pada sel bakteri non phatogen. Perubahan phenothyphic, urgen, ini merupakan rekayasa genetika pertama. “Sesuatu” agent transforming yang sekarang ini dikenal dengan deoxyribose nucleic acids (DNA). Perubahan urutan DNA dapat mengubah phenothyphic atau telah terjadi transformasi sel. Mati hidupnya makhluk hidup adalah terkait erat dengan urutan DNAnya. Kajian DNA menghasilkan cabang-cabang ilmu baru seperti rate mutation dan evolution, drug design, migraton history, kajian gen musics, antropology dan forensics molecular dan sebagainya. Metode structural equation modelling (SEM) digunakan untuk mengetahui respon publik terkait tulisan ini. Berikut ini hasil evalusi pretest dan post test terhadap 32 responden mahasiswa sain kajian X dan 12 kajian Y; berturut-turut sebagai berikut; sangat mengerti (9,37), mengerti (77,1), kurang mengerti (11,47) dan tidak mengerti (2,03); dan sangat mengerti (5,55), mengerti (72,78), kurang mengerti (16,67) dan tidak mengerti (4,15). Secara umum, mahasiswa kajian X lebih mengerti daripada mahasiswa kajia Y walaupun perbedaannya tidak signican.Kata kunci: DNA, Phenotyphic dan transformasi sel
Sosialisasi Tentang Pentingnya Pencegahan Jentik pada Fase Aquatik dan 4M plus (Kelurahan Guntung Manggis Banjarbaru)
Authors: Affandi Pardi Affandi , Thresye Thresye , Q Mariatul , Andriyani Andriyani , A Anjel , Mawardi Mawardi , Aisyah Aisyah
Published: March 2024

Data Profil Kesehatan Provinsi Kalimantan Selatan pada tahun 2020 menginformasikan bahwa penyakit yang disebabkan oleh Dengue erat kaitannya dengan kondisi lingkungan dan perilaku masyarakat yang masih kurang dalam melakukan 4M plus yaitu menguras tempat penampungan air, mengubur barang bekas, menutup tempat penampungan air supaya tidak dijadikan tempat perindukan nyamuk, serta memantau jentik secara rutin. Selain itu faktor aquatik juga sangat penting dipahami sehingga dapat melakukan pencegahan terhadap jentik secara dini. Hal ini dapat mencegah pertumbuhan nyamuk penyebab DBD dengan cepat. Faktor-faktor ini menjadi penyebab penyakit DBD bersifat endemik baik di daerah perkotaan maupun pedesaan.  Salah satu daerah Banjarbaru yang banyak terjadi DBD adalah di Kelurahan Guntung Manggis Kecamatan Landasan Ulin Kota Banjarbaru Provinsi Kalimantan..
PKM Pengolahan Nira Dari Pohon Aren (Arenga Pinnata) Di Desa Munggu Raya Kecamatan Astambul Kabupaten Banjar Provinsi Kalimantan Selatan
Authors: Yamani Ahmad , Basuki Sunarno , Rahmah Siti
Published: March 2024

Pengolahan nira dari pohon aren di Desa Munggu Raya menghasilkan produk minuman sehat. Nira aren dikemas warga dengan plastik seadanya atau dengan botol bekas kemasan air mineral, terkadang dimasukkan kedalam tabung bambu dan jika dipasarkan kekonsumen langsung dituangkan ke dalam gelas. Warga Desa Munggu Raya sangat ingin mendapatkan keterampilan yang dapat meningkatkan kesejahteraan hidup mereka. Permasalahan yang dihadapi mitra adalah peralatan produksi masih tradisional, pengemasan air nira aren dan manajemen usaha. Tujuan kegiatan pengabdian adalah untuk meningkatkan ilmu pengetahuan dan teknologi pengolahan dan pengemasan air nira aren serta manajemen usaha (cara pemasaran dan pembukuan yang sederhana). Metode yang diterapkan yaitu melakukan penyuluhan dan diskusi, pelatihan produksi, pemantauan dan evaluasi. Hasil pengabdian Mitra PKM mampu menerapkan Iptek dalam proses produksi air nira aren. Selain produksi meningkat 100% juga kemasan produk air nira dari pohon aren tradisional menjadi lebih modern serta sistem pemasaran dan manajemen usaha mulai diterapkan oleh mitra. Pembinaan dan kerjasama dengan instansi terkait untuk mengembangkan usaha pengolahan air nira dari pohon aren tradisional di Desa Munggu Raya ini perlu dilakukan agar masyarakatnya lebih Sejahtera.
Konsep Arsitektur Islam pada Perancangan Masjid Hijratul Hidayah, Banjarmasin
Authors: Dahliani Dahliani , Oktaviana Anna , Huzairin Muhammad Deddy
Published: March 2024

Masjid merupakan tempat ibadah umat Islam di kawasan permukiman. Salah satu masjid di Banjarmasin adalah Hijratul Hidayah, yang semakin hari jamaahnya semakin bertambah, sehingga perlu adanya penambahan ruang. Perancangan masjid ini menggunakan konsep arsitektur Islam dengan menerapkan 3 kaidah yaitu keesaan, keindahan dan ekonomis. Konsep diterapkan pada fungsi dan bentuk bangunan. Kaidah keesaan diterapkan pada adanya mihrab sebagai orientasi utama masjid dan menara yang tinggi vertikal sebagai hubungan yang agung kepada Allah SWT. Kaidah keindahan diterapkan dengan penggunaan ornamen Islam pada tampilan bangunan dan bentuk kubah. Kaidah ekonomis diterapkan pada bentuk segiempat pada ruang masjid dan posisi masjid yang berorientasi ke kiblat. Keadaan ini memudahkan pengaturan shaft saat shalat berjama’ah, sehingga tidak ada ruang yang mubazir atau terbuang.
PKM Pengembangan Kerajinan Berbahan Limbah Pertanian di Kelurahan Guntung Manggis Banjarbaru
Authors: Istikowati Wiwin Tyas , Sutiya Budi , Sunardi Sunardi
Published: March 2024

Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan mitra dalam pemanfatan limbah pertanian berupa kulit jagung yang banyak terdapat di lingkungan mitra. Kulit jagung jika tidak dikelola dengan baik bisa berdampak pada pencemaran tanah dan air di lingkungan mitra. Mitra adalah kelompok masyarakat di Kelurahan Guntung Manggis yang membuat beberapa kerajinan dengan bahan kain dan plastik. Pelatihan dilakukan oleh tim pengabdi dengan memanfaatkan limbah pertanian berupa kulit jagung. Kulit jagung dimanfaatkan sebagai bahan baku pembuatan kertas dan juga bisa dioleh menjadi bahan kerajinan yang memiliki nilai ekonomi lebih tinggi. Kegiatan dilakukan dengan membuat kerajinan berupa bunga hias, tempat tissue dan kotak minuman dengan hiasan berbahan limbah kulit jagung. Kegiatan diikuti dengan antusias oleh mitra dan dari kegiatan ini mitra memperoleh peningkatan dalam pengetahuan dan keterampilan dalam pemanfaatan libah pertanian.
Sosialisasi Pencegahan Perundungan Dan Kekerasan Seksual Bawah Sadar Di Pondok Pesantren Putra Darul Istiqamah Barabai
Authors: Ifrani Ifrani , Utami Suci , Hanifah Lena
Published: March 2024

Pengabdian masyarakat ini diharapkan dapat memberikan pemahaman dan kesadaran hukum kepada generasi muda Pondok Pesantren Putra Darul Istiqamah Barabai untuk mengembangkan karakter yang sesuai dengan norma hukum dan agama. Isu perundungan dan kekerasan seksual bawah sadar menjadi permasalahan dalam penyelenggaraan pendidikan yang aman  sehingga diperlukan intervensi untuk mitigasi dan pencegahan perundungan dan kekerasan seksual bawah sadar di lingkungan pondok pesantren, keluarga, dan lingkungan sosial lainnya. Metode yang digunakan dalam pengabdian masyarakat ini adalah penyuluhan hukum dengan pendekatan yuridis sosio-legal melalui ilmu kriminologi dan viktimologi  yang termuat dalam perilaku keseharian para santri dilanjutkan dengan materi peran hukum terkait terhadap perundungan dan kekerasan seksual yang tidak disadari tersebut terjadi di masyarakat. Hasil dari kegiatan ini adalah kesadaran hukum santri Pondok Pesantren Putra Darul Istiqamah mengalami peningkatan setelah menerima penyampaian sosialisasi yang bermuatan hukum dan pencegahan perundungan dan kekerasan seksual. Pada dasarnya memiliki kesadaran hukum yang baik terhadap pencegahan perundungan dan kekerasan seksual. Hal ini terlihat dari antusiasme yang tinggi dan banyaknya pertanyaan kritis yang diajukan oleh peserta penyuluhan. Meskipun demikian, masih banyak yang belum tersampaikan dan beberapa masih kesulitan memahami mengapa kekerasan seksual adalah bagian dari kekerasan berbasis gender. Penting untuk selanjutnya diberi sosialisasi lanjutan khususnya yang berkaitan tentang perlindungan data pribadi di ruang digital agar para santri tidak impulsif  dalam berbagi informasi dalam pemanfaatan gawai dan beraktivitas di ruang digital, khususnya terkait konten-konten yang dapat melampaui batas-batas norma hukum maupun norma asusila di dunia nyata.
Upaya Peningkatan Pendapatan Ibu-Ibu Di Wilayah Sungai Andai Melalui Pembuatan Kerajinan Tas Purun Hias
Authors: Swandari Fifi , Said Laila Refiana , Fariany Gusti Rina , Armea Listi , Rahmatika Ditta
Published: March 2024

Ibu rumah tangga terkadang menjadi tokoh sentral dalam mengatasi kurangnya pendapatan keluarga. Sebagian ibu di Sungai Andai Banjarmasin menambah penghasilan dengan menjadi pengrajin tas purun hias dan membentuk perkumpulan. Perkumpulan tersebut dinamai “Purun Cantiq”. Perkumpulan tersebut terbentuk dari hasil kegiatan pengabdian tahun 2022. Tas purun hias yang diproduksi Purun Cantiq telah mencapai ratusan unit. Namun demikian, produknya masih dianggap tidak mampu memenuhi selera segmen pasar kelas menengah atas. Permasalahan yang ditemukan adalah kurangnya daya saing terkait desain, motif, bahan baku dan kurangnya SDM.  Tujuan pengabdian tahun 2023 ini  adalah meningkatkan pendapatan ibu-ibu yang tergabung dalam Kelompok Usaha Purun Cantiq. Solusi atas masalah tersebut ada beberapa hal: (1) ceramah tentang keinginan segmen pasar kelas menengah dalam hal ini Business Model Canvas (BMC), (2) pelatihan membuat tas purun yang lebih berkualitas dengan sulam pita dan benang rajut dan (3) mencari sumber bahan setengah jadi baru dan (4) merekrut anggota baru. Narasumber yang dihadirkan adalah narasumber yang kompeten. Berbagai kegiatan yang direncanakan telah dilaksanakan dengan baik. Tujuan utama kegiatan pengabdian ini yaitu meningkatkan pendapatan ibu-ibu anggota Purun Cantiq relatih telah tercapai. Hal penting lainnya, kegiatan ini juga mampu meningkatkan daya saing seperti yang telah ditetapkan sebelumnya. Hal ini terlihat dari semakin bagusnya produk yang dibuat dan semakin banyak diminati pelanggan.
Penyuluhan Asal Mula Teknologi Polymerase Chain Reaction Bagi Komunitas Minggu Raya (Bagian 2)
Authors: Susilo Tanto Budi , Soesanto Oni , Susanti Dewi Sri , Fahrudin Arfan Eko , Suhartono Eko , Hidayat Yuyun , Wahjono Sri Cahyo , Soendjoto Muchamad Arief , Krisdianto Krisdianto
Published: March 2024

Program kegiatan masyarakat (PKM) ini merupakan bagian edukasi publik terhadap masa endemi or post-covid-19. Ulasan PKM sebagai berikut ini; Setelah penentuan struktur DNA oleh Watson-Crick, setelah amplifikasi dan pengurutan DNA oleh Mullis dan Sanger, selanjutnya Human Genome Project mambaca 3,055 milyar urutan pasang basa manusia abad 21 ini. Bank-bank data DNA/protein atau informasi biologi telah berdiri seperti; NCBI, DDBJ dan EMBI telah memuat lebih 500 juta urutan DNA berbagai jenis species. Bank ini sumber genomics, proteomics, metabolomics dan economics sekaligus, pada masa depan. Bagi Carpentier dan Daudna bukan hanya sekedar jumlah urutan DNA yang luar biasa tetapi harta karun yang tidak ternilai harganya, mengapa? Karena dia tidak buta huruf membaca urutan DNA, karena dia mampu memilih dan memilah mana fragmen yang palindromics mana yang bukan. Mana yang genes musics mana yang bukan. Mana genes memory penyandi antibody mana yang bukan. Ringkasnya seluruh persoalan genetic tubuh manusia dapat dibaca, di Human Genom Project ini. Jadi, apakah kita tetap ingin menutup mata. Metode structural equation modelling (SEM) dengan uji pretest dan post test terhadap tulisan asal usul PCR ini. Hasil uji ditunjukan kepada 32 responden berumur kisaran 18 tahunan dan 12 responden berumur kisaran 19 tahunan, berturut-turut sebagai berikut; sangat mengerti (0), mengerti (80,55), kurang mengerti (19,45) dan tidak mengerti (0); dan sangat mengerti (4,16), mengerti (82,83), kurang mengerti (13,03) dan tidak mengerti (0). Respon terhadap urgensi epistemologi PCR, untuk yang merumur 19 tahunan lebih mengerti daripada responden yang berumur 18 tahun, walaupun perbedaannya tidak nyata.
Seni Musik Tifa Sebagai Media Pembelajaran Sejarah Afrika-Papua Di Rusunawa Banjarbaru
Authors: Susilo Tanto Budi , Krisdianto Krisdianto , Manik Tetti Novalina , Thresye Thresye
Published: March 2024

Tulisan ini, bagian program pengabdian masyarakat; dengan judul “Podcast: Seni sebagai media pembelajaran sains” tiga tahun lalu. Berikut ini ulasannya; tifa atau Jimbe (bahasa Mali, djembe: kumpul) merupakan instrumen musik modern dan/atau kontemporer yang berasal dari negara Jamaica, Amerika Tengah. Instrumen ini mengandung memori dan simbolisasi penindasan bangsa Mali-Afrika Barat, dihinakan, dihewankan dan diperbudak oleh bangsa Spanyol, di benua Amerika, era kolonialisasi (abad 15-17), sebelum pindah kuasa ke Inggris (abad 17-19). Adalah dia, manusia Afrika Barat menyuarakan dan mengekspresikan sedihnya di atas drum, bedug atau djembe/kendang. Era milinialisasi, Si Mali, Si Jimbe hadir kembali untuk menghibur, untuk menuntun perasaan bangsa manusia dengan nada tersendiri dan unik. Terdapat tiga nada pada jimbe; nada tinggi ada di bagian tepi jimbe, sedang ada di bagian agak tengah jimbe dan rendah ada di bagian tengah jimbe. Patitur jimbe terletak pada cara drummer memainkan dengan kecepatan dan variatif. Metode Structural Equation Modelling (SEM) digunakan untuk mengetahui persepsi mahasiswa terhadap performance lagu Tifa Afrika, sebagai berikut; sangat mengerti (14,8%), mengerti (56,5%), kurang mengerti (28,2%) dan tidak mengerti (0,5%). Diharapkan seni musik dapat digunakan sebagai media untuk pembelajaran sain sosial dan sain natural.
Pemanfaatan Sampah Organik untuk Budidaya Sayuran Organik dengan Sistem Vertikultur
Authors: Ismuhajaroh Bakti Nur , Susanti Hilda , Sukmana M. Laily Qadry , Jawak Gani , Juharni Juharni , Fadhiel Muhammad Ihsan , Halim Andi Rahman
Published: March 2024

Pemenuhan kebutuhan gizi khususnya sayuran yang sehat di masyarakat perkotaan memerlukan biaya yang tinggi. Ketersediaan lahan yang sempit dan kurangnya pengetahuan menyebabkan rendahnya minat budidaya tanaman masyarakat perkotaan. Pemanfaatan sampah organik limbah rumah tangga untuk budidaya sayuran secara organik dengan sistem vertikultur dapat meningkatkan kemampuan masyarakat dalam mengelola sampah rumah tangga dan produksi sayuran sehat.  Kegiatan ini dilaksanakan di RT. 40 dan RT. 47, RW. 07 Kelurahan Guntung Manggis, Kecamatan Landasan Ulin, Kota Banjarbaru, Kalimantan Selatan. Tahapan kegiatan yang dilakukan adalah sosialisasi, praktik pembuatan demplot, dan monitoring. Pelaksanaan kegiatan ini secara berkelanjutan akan meningkatankan kondisi lingkungan, memenuhi kecukupan gizi rumah tangga dan meningkatkan pendapatan keluarga.
Perakitan Mandiri PCR Sederhana Untuk Pembelajaran Amplifikasi DNA In Vitro
Authors: Susilo Tanto Budi , Soesanto Oni , Susanti Dewi Sri , Fahrudin Arfan Eko , Elma Tiara , Hidayat Yuyun , Sutomo Sutomo , Badruzsaufari Badruzsaufari , Savalas Lalu Rudyat Telly
Published: March 2024

Pada dua dekade terakhir, Polymerase Chain Reaction (PCR) merupakan suatu metode yang digunakan dalam kurikulum pendidikan sains terutama terkait erat dengan matakuliah bioinformatika pada sains biologi, kimia, farmasi, fisika, statistika, dan matematika. Metode ini berupa alat yang mampu mengamplifikasi DNA secara luar sel (in vitro). Prinsip metode PCR adalah mengukur aktivitas enzim DNA polymerase dengan indikator amplifikasi DNA secara in vitro. Sedangkan, perakitan mengunakan elemen pemanas, regulator arus listrik dan chamber. Alat ini dirangkai di Laboratorium Organik dan Biokimia, Program Studi Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) Universitas Lambung Mangkurat (ULM). Untuk validasi metode PCR rakitan mengunakan fragmen cox mtDNA ikan kihung (Channa lucius) dan telah dipraktekkan oleh mahasiswa semester 5 Program Studi kimia dan matematika. Elaborasi dengan metode Structural Equation Modelling (SEM) digunakan untuk mengetahui persepsi mahasiswa terhadap alat PCR sederhana ini. Selanjutnya, sebanyak 48 mahasiswa memberikan respon terhadap perakitan alat PCR sederhana. Hasilnya adalah responden sangat mengerti (9,70%), mengerti (75,72%), kurang mengerti (14,58%) dan tidak mengerti (0%). Sehingga perakitan alat PCR sederhana ini diharapkan menjadi alternatif untuk penguatan kurikulum pendidikan sains.Kata kunci: PCR, DNA polymerase
The Collatz Conjecture: A New Proof using Algebraic Inverse Trees
Authors: Diedrich Eduardo
Published: March 2024

This article introduces the Theory of Inverse Discrete Dynamical Systems (TIDDS), a novel methodology for modeling and analyzing discrete dynamical systems via inverse algebraic models. Key concepts such as inverse modeling, structural analysis of inverse algebraic trees, and the establishment of topological equivalences for property transfer between a system and its inverse are elucidated. Central theorems on homeomorphic invariance and topological transport validate the transfer of cardinal attributes between dynamic representations, offering a fresh perspective on complex system analysis. A significant application presented is an alternative proof of the Collatz Conjecture, achieved by constructing an associated inverse model and leveraging analytical property transfers within the inverted tree structure. This work not only demonstrates the theory's capability to address and solve open problems in discrete dynamics but also suggests vast implications for expanding our understanding of such systems.
Analysis of the Influence Port Development on Economic Growth in Djibouti: In the Case of Doraleh Container Terminal
Authors: Abdillahi Waberi Abdorahman
Published: March 2024

Djibouti shares an exceptional geostrategic position by being close to one of the busiest maritime routes, which makes it possible to have a crucial position for the movement of international trade transported by sea. This study analyses the influence of port development on Djibouti’s economic growth in the case of Doraleh Container Terminal and identifies other significant variable factors. In this paper, we analyze the existence of an influence port development on economic growth and other variables, by applying the perspective of the multiple regression model in the analysis using Eviews software. the selected datasets in the analysis cover the period from 2010 to 2020. The result show that port development has a direct and strongly positive influence on the economic growth of Djibouti. In addition, this study also reveals that imports and exports trade is a mediating variable with a significant influence on economic growth in Djibouti. Furthermore, foreign direct investment has not directly and positive influences on Djibouti's economic growth. Therefore, we recommend that the Government of Djibouti attract and promote the benefits of foreign direct investment to enhance the development of various economic sectors and achieve significant economic growth in the coming years.
The Gut Connection: Exploring The Possibility Of Implementing Gut Microbial Metabolites in Lymphoma Treatment
Authors: Al-Khazaleh Ahmad K. , Chang Dennis , Münch Gerald W. , Bhuyan Deep Jyoti
Published: March 2024

Recent research has implicated the gut microbiota in the development of lymphoma. Dysbiosis of the gut microbial community can disrupt the production of gut microbial metabolites, thereby impacting host physiology and potentially contributing to lymphoma. Dysbiosis-driven release of gut microbial metabolites such as lipopolysaccharides can promote chronic inflammation, potentially elevating the risk of lymphoma. In contrast, gut microbial metabolites, such as short-chain fatty acids, have shown promise in preclinical studies by promoting regulatory T-cell function, suppressing inflammation, and preventing lymphoma. Another metabolite, urolithin A, exhibited immunomodulatory and antiproliferative properties against lymphoma cell lines in vitro. While research on the role of gut microbial metabolites in lymphoma is limited, this article emphasizes the need to comprehend their significance, including therapeutic applications, molecular mechanisms of action, and interactions with standard chemotherapies. The article also suggests promising directions for future research in this emerging lymphoma and gut microbiome investigation field.
SSR Markers-Based DNA Fingerprinting for Varietal Identification in Mango Cultivars
Authors: Iqbal Javed , Ashraf Muhammad Aleem , Kashif Muhammad , Paray Bilal Ahamad
Published: March 2024

Mango (Mangifera indica L.) is an allotetraploid (2n = 4X= 40) drupe fruit and has high nutritional value belongs to genus Mangifera and family Anacardiaceae. Mango cultivars are used with worldwide acceptance to pharmacological, ethnomedical, and phytochemical industries. Assessment of the genetic distinctiveness of a cultivar through morphological descriptors is an important tool for both the registration and the protection. New mango genotypes have been improved using valuable diverse germplasm resources to ensure food security. DNA fingerprinting based simple sequence repeats (SSR)-markers have been the most broadly used, effective and accurate in evaluation of genetic characterization of a cultivar. Molecular breeding is an effective source of genetic gain after improvement of fruit trees using marker assisted genomic selection. Total genomic DNA (gDNA) was generated using CTAB method from each cultivar. The most effective 50 hyper-variable SSR markers were selected. Highly specific DNA fingerprints were identified in the candidate line ‘Azeem Chaunsa’ compared with three standard cultivars using SSR-PCR. An agglomerative hierarchical clustering method was used to construct dendrogram based on the UPGMA clustering method. Cultivar identification diagram (CID) was constructed to evaluate association among standard cultivars and Azeem Chaunsa. Our results showed that SSR markers could efficiently assess genetic diversity in mango. The genetic similarity coefficients were recorded between the cultivars of mango ranged from 0.49 to 0.67. CID results concluded that cultivar ‘Azeem Chaunsa’ varied significantly from the check cultivar, Sindhri (46.2%), S.B Chaunsa (45%) and Sufaid Chaunsa (46.7%). The results obtained in this study will orient cultivar identification strategies for a successful future.
Interpreting Diastolic Dynamics and Evaluation Through Echocardiography
Authors: Zhang Xiaoxiao , Li Ke , Cardoso Cristiano , Moctezuma-Ramirez Angel , Elgalad Abdelmotagaly
Published: March 2024

In patients with heart failure, the evaluation of left ventricular (LV) diastolic function is vital, offering crucial insights into hemodynamic impact and prognostic accuracy. Echocardiography stands as the primary imaging modality for diastolic function assessment, and using it effectively requires a profound understanding of the underlying pathology. This review covers four main topics: first, the fundamental driving forces behind each phase of normal diastolic dynamics, along with the physiological basis of two widely used echocardiographic assessment parameters, E/e' and mitral annulus early diastolic velocity (e'); second, the intricate functional relationship between the left atrium and LV in patients with varying degrees of LV diastolic dysfunction (LVDD); third, the role of stress echocardiography in diagnosing LVDD and the significance of parameter changes in this context; and fourth, the clinical utility of evaluating diastolic function from echocardiography images across diverse cardiovascular care areas.
The Generalized Eta Transformation Formulas as the Hecke Modular Relation
Authors: Wang Nianliang , kuzumaki Takato , Kanemitsu Shigeru
Published: March 2024

Transformation formula under the action of a general linear fractional transformation for generalized Dedekind eta-function has been a subject of intensive study, Rademacher, Dieter, Meyer et al. However, the (Hecke) modular relation structure has not been recognized until the work of Goldstein-de la Torre, and streamlining the classical proofs in the modular relation will reveal the meaning hidden in those works. Our main aim is to elucidate the works of these researchers in the context of modular relations.
Thermodynamical Metrics in General Relativity Theory
Authors: Haug Espen
Published: March 2024

We demonstrate that multiple well-known metrics, such as the Schwarzschild metric and the extremal solution of the Reissner-Nordstr ̈om metric, can be expressed in what we will call thermodynamic form. These formulations appear to be valid for all Rs = ct growing black holes and, therefore, also within the framework of Rh = ct growing black hole cosmology. However, the metrics can also be applied to non-black hole gravitational objects as long as one calculates the CMB and Hawking temperature of the hypothetical black hole from the gravitational mass.
Impact of Utilizing Visual Stimuli (BlazePod) on Agility, Vertical jump, and Visual Reaction Time Speed in Under-19 Volleyball Players
Authors: Zekailiche Youssef , Bougrine Houda , Khalfoun Jihen , Jebabli Nidhal , Djeddi Rachad , Saad Saoud Foued , Ben Abderrahman Abderraouf
Published: March 2024

This study aimed to evaluate the effects of Blazepod technology when incorporated with various training regimens on the essential elements of physical fitness in volleyball, such as agility, speed, visual response time, and vertical leap. Thirty-six participants (age :17.33±0.48 y, height: 183.78±6.34 cm, weight: 77.14±5.16 kg) were in-volved in this study. In randomized design, three equal groups with two experimental groups and one control group were involved in the study over a period of six weeks: (GE1) used Blazepod technology to workout at a low level; (GE2) used Blazepod technology to workout at a higher intensity; (CG) did not employ Blazepod technology, but it adhered to the same fundamental training curriculum. We conducted agility, speed, reaction time, and vertical jump tests before, midway and after the study to determine optimal training volume, intensity, and frequency. A significant main effect of time (P0.01), and time×group interaction (P>0.001) were found for all tests. Post hoc test showed that the two experimental groups gadget significantly improved in all performance variables (P
Sustainability-Oriented Innovations and Smart Farming Technologies in Wine Value Chains: Assessing their Impact on Sustainability Performance
Authors: Kasimati Aikaterini , Papadopoulos George , Manstretta Valentina , Giannakopoulou Marianthi , Adamides George , Neocleous Damianos , Vassiliou Vassilis , Savvides Savvas , Stylianou Andreas
Published: March 2024

Addressing the urgent sustainability challenges in the wine industry, this study explores the efficacy of sustainability-oriented innovations (SOIs) and smart farming technologies (SFTs) across wine value chains in Cyprus and Italy. Employing KPIs for a rigorous assessment, the research delves into the environmental, economic, and social impacts of these technologies. In Cyprus (SIP7), the integration of digital labelling and smart farming solutions led to a substantial reduction in pesticide usage by up to 75% and enhanced the perceived quality of wine by an average of 8%. Italy's SIP10 witnessed a 33.4% decrease in greenhouse gas emissions, with an additional benefit of a 5.3% improvement in intrinsic product quality. Notably, SIP10 also introduced a carbon credit system, potentially generating an average annual revenue of €4,140 per farm. These findings highlight the transformative potential of SOIs and SFTs in promoting sustainable practices within the wine industry, demonstrating significant advancements in reducing environmental impact, improving product quality, and enhancing economic viability. The study underscores the critical role of innovative technologies in achieving sustainability goals and provides a compelling case for wider adoption within the agricultural sector.
Mechanical Behavior of Dental Restorations Implant-Supported vs MultiUnit-Supported Restorations, a Finite Element Pilot Study
Authors: Anitua Eduardo , Díez Patricia Truchuelo , Pesquera Velasco Jorge , Larrazabal Saez de Ibarra Naiara , Armentia Mikel , Seco-Calvo Jesus
Published: March 2024

Implant-supported-screw-retained prostheses are really popular. Some of the most frequent complications have been mechanical complications. These include abutment screw loosening or even screw fracture. Using an intermediate abutment can offer several advantages. However, little literature has been found regarding how this affects the mechanical behavior of dental restorations. This study focuses on understanding the mechanical behavior of implant-supported restorations with a transepithelial component compared to those with a direct implant-supported restoration. It was carried out by using the Finite Element Method (FEM) and was experi-mentally validated. The results showed that in the case of transepithelial-supported restoration, the prosthetic screw mounted over the transepithelial component suffers higher stress than the one screwed directly to the implant. After applying a cyclic fatigue load, it is experimentally proven that, in the transepithelial-supported restorations, the fuse changes from being the screw that goes to the implant, to being the upper one. As a conclusion we can say that the use of an intermediate abutment in dental restoration not only provides better protection to the rest of the dental restoration but also allows easier repair in the event of a fracture. This can potentially lead to more efficient procedures and improved patient outcomes.
Mechanism of Malignancy Development When the Metabolism of the Human Body Deteriorates
Authors: kato manabu
Published: March 2024

Globally, cancer is an important health problem worldwide, and has become one modern medicine’s most serious problems to prevent, diagnose, and treat. Many types of cancers still have non-negligible mortality rates, and new treatments need to be developed for them. This study aimed to elucidate cancer mechanisms and facilitate cancer treatment and prevention. The ideal temperature for cancer growth is 35°C; however, conditions were not consistent with chromosomal instability, loss of alleles of tumor-suppressor genes, abnormal DNA methylation, and collagen phagocytosis, which are known causes of cancer. In addition, when cancer develops, white blood cells attack the cancer tissue and remove it; however, as the decrease in body temperature drops, leads to a reduction in the immune potential of the white blood cells. Based on previous papers, this study focused on aimed to determine the effects of the low-temperature environment of 35°C, the temperature at which cancer is most likely to proliferate, and changes in adenosine triphosphate (ATP) levels. The study revealed that Therefore, the causes of cancer is caused by include chromosome fusion that occurs occurring due to the impaired DNA topoisomerase IIα proliferation and primary cilia rotation due to resulting from decreased intercellular adhesion.
New Insight into Laryngo-Tracheal Surgery: High-Flow Oxygen Therapy to Prevent Early Complications after Surgery
Authors: Trabalza Marinucci Beatrice , Fiorelli Silvia , Siciliani Alessandra , Menna Cecilia , Tiracorrendo Matteo , Massullo Domenico , Venuta Federico , Rendina Erino Angelo , Ciccone Anna Maria , D'Andrilli Antonio , Ibrahim Mohsen , Maurizi Giulio
Published: March 2024

Background: Early postoperative airway management after laryngo-tracheal surgery is crucial. Acute respiratory failure due to glottis’ oedema may occur, requiring reintubation. This can prolong ventilatory assistance, jeopardizing the anastomosis. To date, only judicious steroid administration and fluid management are available to avoid more invasive procedures. High-Flow-Oxygen-Therapy(HFOT) is a noninvasive O2 support method providing humidification, warmed air, Positive-End-Expiratory-Pressure(AIRVO2). No data exist about HFOT use to prevent early complications after laryngo-tracheal surgery. Methods: Between Sept.2020-Sept.2022, 107 consecutive patients underwent laryngo-tracheal surgery received HFOT(Group A). Data and long-term results were compared with those of 80 patients operated between Sept.2018-Aug.2020(Group B), when HFOT was not available. All patients were operated in a single center. No pre- or post-operative settings changed, except for HFOT introduction. We analyzed and compared the risk for “delayed” reintubation (unexpected reintubation within the first 24-48 hours after extubating/laryngeal mask removal) in the two groups. Results: No patients reported HFOT-related adverse events. Control group(B) presented “delayed” reintubation in 37% (p= 0.027), Intensive Care Unit admission in 67%(p=0.005) and longer hospital stay(p=0.001) compared to HFOT group(A). Minor complications rate was 3% in both group and overall mortality was 0%. Re-stenosis was described in 4.6% of HFOT group, without a statistically significant difference (p=0.7006). Conclusions: Our study is the first to investigate HFOT use in patients undergoing laryngo-tracheal surgery, potentially representing a consistent innovation in the peri-operative management of these patients. With the limit of a retrospective series, we would suggest HFOT use for preventing post-operative reintubation rate, possibly reducing ICU admission and hospital stay.
Prospective Observational Study of Oral Health in Hospitalized Diabetic Patients in the Internal Medicine Service of the Morales Meseguer Hospital
Authors: Redondo-Ruiz Jose , Pinar-Sanchez Juana , Pecci-Lloret Miguel R. , Rodríguez-Lozano Francisco Javier , Oñate-Sánchez Ricardo Elías
Published: March 2024

Keywords: Oral health, diabetes, periodontal disease, caries, periodontitis.
A Draft Design of a Zero Power Experiment for Molten Salt Fast Reactor Studies
Authors: Merk Bruno , Noori-kalkhoran Omid , Jain Lakshay , Aflyatunova Daliya , Jones Andrew , Powell Lewis , Detkina Anna , Drury Michael , Litskevich Dzianis , Viebach Marco , Lange Carsten
Published: March 2024

The UK government and many international experts have pointed out that nuclear energy has an important role to play in the transition towards a decarbonized energy system since it is the only freely manageable very low-carbon energy technology with 24/7 availability to complement renewables. Besides current investments in light water reactor technologies, we need innovation for improved fuel usage and reduced waste creation, like offered by iMAGINE, for the required broad success of nuclear technologies. To allow quick progress into innovative technologies like iMAGINE and their regulation, a timely investment into urgently needed experimental infrastructure and expertise development will be required to assure the availability of capacities and capabilities. The initial steps to start the development of such a new reactor physics experimental facility to investigate molten salt fast reactor technology are discussed and a stepwise approach for the development of the experimental facility is described. The down selection to the choice for a diverse control and shutdown system is described through manipulating the reflector (control) and splitting the core (shutdown). The developed innovative core design of having the two core parts in two different rooms opens completely new opportunities and will allow to manifest the request for separated operational and experimental crews, as nowadays requested by regulators into the built environment. The proposed physical separation of safety relevant operational systems from the experimental room should on the one hand help to ease the access to the facility for visiting experimental specialists. On the other hand, the location of all safety relevant systems in a now separated access-controlled area for the operational team will limit the risk of misuse through third party access. The planned experimental programme described with the major steps: core criticality experiments, followed by experiments to determine the neutron flux, neutron spectrum, and power distribution as well as experiments to understand the effect of changes in reactivity and flux as a function of salt density, temperature and composition change.
Epidemiological Characterization of Dengue Virus Serotypes in Mexico: Implications for Disease Severity
Authors: Hernández Bautista Porfirio Felipe , Cabrera Gaytán David Alejandro , Santacruz-Tinoco Clara Esperanza , Vallejos Parás Alfonso , Alvarado Yaah Julio Elias , Martínez-Miguel Bernardo , Anguiano Hernández Yu Mei , Arriaga Nieto Lumumba , Moctezuma Paz Alejandro , Jaimes Betancourt Leticia , Pérez Andrade Yadira , Orozco Oscar Cruz , Valle Alvarado Gabriel , Rivera Mahey Mónica Grisel
Published: March 2024

Dengue fever remains a persistent threat in Mexico, with cyclical outbreaks driven by the circulation of multiple dengue virus serotypes. The sudden emergence of DENV-3 in 2023 raised questions about its epidemiological significance and potential implications for disease severity. This study aimed to characterize dengue virus serotypes by age and their association with disease severity, considering sex, time, and the origin of clinical samples. A retrospective analysis was conducted on dengue laboratory results obtained from the epidemiological surveillance system in Mexico during 2023. Descriptive statistics summarized the prevalence of dengue virus serotypes, while bivariate analysis utilized an adjusted Chi-squared test to assess associations with demographic variables. Multivariate analysis using unconditional logistic regression evaluated the relationship between dengue virus serotypes and disease severity, adjusting for potential confounders. Additionally, co-infections were identified and analyzed. Results revealed DENV-3 as the most prevalent serotype (63.9%), with co-infection involving two serotypes detected in 0.75% of cases. DENV-2 exhibited a higher median age compared to other serotypes. Pregnant women in their last trimester faced elevated risks of hospitalization and mortality. Multivariate analysis indicated a stronger association between DENV-2 and hospitalization. However, co-infection did not significantly influence disease severity. The unexpected predominance of DENV-3 underscores the dynamic nature of dengue virus circulation in Mexico. Despite its prevalence, DENV-2 demonstrated a stronger association with hospitalization, highlighting the importance of serotype-specific surveillance and management strategies.
Radiographic Study of Transcrestal Sinus Floor Elevation Using Osseodensification Technique with Graft Material: A Non-randomized Pilot Clinical Trial
Authors: Sulyhan-Sulyhan Khrystyna , Barberá-Millán Javier , Larrazabal-Moron Carolina , Espinosa-Giménez Julián , Gómez-Adrián María Dolores
Published: March 2024

The study aimed to evaluate implant success and bone height variations after transcrestal sinus floor elevation (tSFE) using the osseodensification technique (OD) combined with beta-tricalcium phosphate (β-TCP), as bone graft material and simultaneous implant placement. Thirteen patients requiring the placement of one implant in the upper posterior maxilla, with a residual bone height of
Fractional Mathematical Models S.V. Dubovsky to Describe K-Waves in Economics
Authors: Makarov Danil , Parovik Roman
Published: March 2024

The article is devoted to the research of economic cycles and crises, which are studied within the framework of the theory of long waves by N. D. Kondratiev (K-waves) using the mathematical apparatus of fractional calculus. The object of the study is the mathematical model of S.V. Dubovsky 3 and some of its modifications, which describe the dynamics of the economic system, characterizing the interaction between the efficiency of new technologies and the efficiency of capital productivity. Modifications in the model are determined by the following points: the mathematical model takes into account the dependence of the rate of accumulation on capital productivity, there is an external harmonic influence - the influx of investments and new technological solutions, the economic system has heredity, including time-dependent, which leads to a delayed effect - the system’s response to impact. The property of heredity in the mathematical model is taken into account using fractional derivatives of constant and variable orders. Mathematical model S.V. Dubovsky and its modifications are studied numerically using the Adams-Bashforth-Moulton algorithm. Oscillograms and phase trajectories are constructed, and an interpretation of the simulation results is given.
p53 Immunohistochemistry Defines a Subset of Human Papillomavirus-Independent Penile Squamous Cell Carcinomas with Adverse Prognosis
Authors: Trias Isabel , Algaba Ferran , De Torres Inés , Saco Adela , Marimon Lorena , Peñuelas Núria , Diez-Ahijado Laia , Sisuashvili Lia , Darecka Katarzyna , Morató Alba , Del Pino Marta , Ferrandiz-Pulido Carla , Ribal Maria J. , Ajami Tarek , Molina Juan Manuel Corral , Gaya Josep M. , Reig Oscar , Ordi Oriol , Ribera-Cortada Inmaculada , García-Herrera Adriana , Rakislova Natalia
Published: March 2024

Background: Penile squamous cell carcinoma (PSCC) is classified into two prognostically distinct types: human papillomavirus (HPV)-associated and HPV-independent. Conversely, the impact of p53 status on prognosis remains controversial. We correlated HPV and p53 status with prognosis in a large series of PSCC patients. p53 was analysed according to a recently described immunohistochemical (IHC) pattern-based framework that includes two normal (scattered, mid-epithelial) and four abnormal patterns (diffuse, basal overexpression, cytoplasmic and null) and closely correlates with TP53 mutational status. Methods: A total of 122 patients with surgically treated PSCC in three hospitals in Barcelona, Spain, were included. Based on HPV in situ hybridization and p16 and p53 IHC expression, the tumors were classified into three molecular types: HPV-associated, HPV-independent/p53 normal, and HPV-independent/p53 abnormal. All patients were followed for at least 22 months (median 56.9 months), and disease-specific survival (DSS) was analysed. Results: Thirty-six tumors (29%) were HPV-associated, 35 (29%) were HPV-independent/p53 normal, and 51 (42%) were HPV-independent/p53 abnormal. Disease-related deaths were observed in 3/36 (8%), 0/35 (0%) and 14/51 (27%) of the patients, respectively (p<0.001). A total of 7/14 deaths in the latter group were patients with tumors showing p53 patterns not recognized in the classical p53 IHC interpretation (basal, null, cytoplasmic). According to our multivariate analysis, HPV-independent/p53 abnormal tumors and advanced stage were associated with impaired DSS (hazard ratio=23.4, 95% confidence interval [CI]= 2.7-3095.3; p=0.001 and 16.3, 95% CI=1.8-2151.5; p=0.008, respectively). CONCLUSION: Compared with patients with HPV-associated and HPV-independent/p53-normal PSCC, patients with HPV-independent/p53 abnormal PSCC have worse clinical outcomes. p53 IHC results define two prognostic categories in HPV-independent PSCC: HPV-independent/p53-normal tumors as low-risk tumors, whereas HPV-independent/p53-abnormal tumors as aggressive neoplasms.
A Method to Estimate Climate Drivers of Maize Yield Predictability Leveraging Genetic-by-Environment Interactions in the US and Canada
Authors: Sarzaeim Parisa , Muñoz-Arriola Francisco
Published: March 2024

Throughout history, the pursuit of diagnosing and predicting crop yields has evidenced genetics, environment, and management practices' intertwined roles in achieving food security. However, the sensitivity of crop phenotypes and genetic responses to weather and climate remains unclear, hampering the identification of the underlying abilities of plants to adapt to climate change. We hypothesize that the PAWN global sensitivity analysis (GSA) coupled with a genetic by environment (GxE) model -built of environmental covariance and genetic markers structures- can evidence the contributions of climate on the predictability of maize yields in the U.S. and Ontario, Canada (US-CA). The GSA-GxE modeling framework estimates the relative contribution of climate variables such as solar radiation, temperature, rainfall, and relative humidity on improving maize yield predictions in US-CA. We use an improved version of the Genomes to Fields (G2F) initiative multi-dimensional database to build the environmental covariance matrices for the proposed GSA-GxE framework. The PAWN indices show that the aggregated GxE model’s highest sensitivity levels over US-CA were attributed to solar radiation, temperature, rainfall, and relative humidity. In one-third of the locations, rainfall was the primary climate variable responsible for maize yield predictability. Also, a consistent pattern of top sensitivity indices by location indicates that Relative Humidity, Solar Radiation, and Temperature were distributed as the main or the second most relevant drivers of maize yield predictability.
A Study of Interface Bond Strength Following Hot Deformation Bonding of AA6061 at Different Temperatures and Loading Rates
Authors: Kayat Moty , Mittelman Brigit , Fadel Dvir , Ben-Haroush Michael , Bortman Jacob , Priel Elad
Published: March 2024

Multilayered metallic sheets fabricated by hot metal forming processes are attractive structural components in the aerospace and automobile industry. The strength of the mechanical bond between the different layers is critical to the applicability of such components in load bearing applications. While it is well understood that the process conditions such as temperature, deformation and rate of deformation influence the bond strength, a clear functional relationship between these conditions and the bond strength has yet to be established. The objective of the current study is to investigate the joining of Aluminum-6061 alloy specimens by hot compression bonding. Hot compression tests of beam specimen pairs were conducted at different temperatures (300-500℃), with different strains and strain rates (10-2-10-1 [1sec]). Coupled thermo-mechanical finite element models were utilized to compute the time dependent thermo-mechanical fields that develop along the specimen interface. The computed values were used to map the spatial distribution of a scalar parameter J which is hypothesized to govern bond formation. Mechanical tensile tests were used to determine the bond strength and expose the bonded surfaces. It is demonstrated that the computed J distribution can be correlated well with SEM observations of the debonded surface. It is also shown that the actual bonded area can be predicted from the computations for a certain range of critical J values.