bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Bisnis Kewirausahaan Produk Pengharum Ruangan yang Berasal dari Limbah Minyak Sayur
Authors: Isnaeni Lusi , Pratomo Amelya , Al-Ihza Rafriansyah , Albarra Hanzhalah
Published: November 2022

Latar Belakang: Minyak goreng merupakan salah satu kebutuhan pokok yang sangat penting bagi masyarakat Indonesia, dibandingkan sembilan bahan pokok selain beras dan kebutuhan pokok lainnya, termasuk minyak sayur. Minyak goreng yang digunakan terus-menerus disebut sebagai minyak jelantah dan kondisi minyak seperti ini akan berdampak pada kesehatan apabila digunakan secara berulang. Perlu adanya solusi untuk mengolah minyak goreng bekas menjadi produk lain yang lebih bermanfaat, salah satunya dengan mengolahnya menjadi pengharum ruangan. Tujuan: untuk membuat produk pengharum ruangan bernama “Luhara” yang berasal dari limbah minyak sayur yang mempunyai nilai jual ekonomis dan ramah lingkungan. Metode Penelitian: terdiri atas tahap persiapan, tahap produksi, tahap pengemasan, tahap pemasaran, tahap pengembangan usaha, dan tahap evaluasi. Hasil: terdiri atas konsep bisnis, analisis pasar, kekuatan produk, target luaran, dan analisis finansial terhadap produk pengharum ruangan “Luhara”. Kesimpulan: bahwa produk pengharum ruangan “Luhara” mempunyai ciri khas aroma rempah-rempah, bernilai ekonomis, dan ramah lingkungan sehingga dapat menjadi pilihan alternatif produk pengolahan limbah minyak sayur menjadi produk lain yang bermanfaat, salah satunya pengharum ruangan.
PENGARUH ELECTRONIC WORD OF MOUTH, CELEBRITY ENDORSER, DAN SOCIAL MEDIA MARKETING TERHADAP BRAND IMAGE PADA PRODUK DI INSTAGRAM
Authors: Putri Belinda Hilda Harsana , Nasution Olivia Barcelona
Published: November 2022

Instagram merupakan salah satu media sosial yang jumlah penggunanya terus meningkat setiap tahunnya. Sehingga, platform ini  banyak digunakan oleh pemasar online untuk memasarkan produk serta melaksanakan strategi pemasaran. Dalam konteks jual beli online, ketidakpastian menjadi isu terbesar dimana adanya asimetri informasi antara pembeli dan penjual. Sehingga, konsumen kerap kali mencari informasi terkait dari ulasan yang diberikan oleh konsumen lain. Selain itu, hal yang meyakinkan konsumen adalah ulasan yang diberikan oleh pihak terpercaya seperti publik figur. Penelitian ini memiliki tujuan untuk mengetahui pengaruh electronic word of mouth, celebrity endorser, dan social media marketing terhadap brand image pada produk di Instagram. Populasi dalam penelitian ini yaitu pengguna aplikasi Instagram. Metode pengumpulan data yang digunakan yaitu dengan menggunakan angket/kuesioner dan jumlah sampel yang digunakan sebanyak 174 responden. Metode analisis data yang digunakan dalam penelitian ini adalah analisis regresi linear berganda. Dari pengujian yang dilakukan, didapatkan hasil penelitian: electronic word of mouth, celebrity endorser, dan social media marketing  berpengaruh signifikan terhadap brand image.
Pengaruh Profitabilitas terhadap Harga Saham
Authors: Barus Stevie Margareth Odelia
Published: November 2022

Tujuan penelitian ini adalah menguji pengaruh Profitabilitas Terhadap Harga Saham Pada Perusahaan Sub Sektor Farmasi Yang Terdaftar Di Bei Periode 2017-2020. Analisis data yang digunakan dalam penelitian ini menggunakan metode purposive sampling. Responden dalam penelitian ini adalah 12 perusahaan sub-sektor farmasi. Sampel dalam penelitian ini 12 perusahaan sub-sektor farmasi periode 2017-2020 atau 4 tahun, namun ada 2 perusahaan tidak mencantumkan harga sahamnya, maka jumlah sampling ada sebanyak 10 perusahaan. Indikator untuk menghitung profitabilitas adalah Return on Asset dan Return on Equity. Indikator untuk menghitung Harga saham adalah nilai dari saham itu sendiri yang diukur dengan harga saham pada saat penutupan. Adapun Jenis penelitian ini adalah penelitian kuantitatif dan jenis data yang digunakan adalah data sekunder berupa laporan keuangan yang didapat melalui http://www.idx.co.id. Hasil penelitian menunjukan bahwa ROA  dan ROE tidak berpengaruh signifikan terhadap harga saham  yang dapat dilihat dari uji t dimana hasil signifikansi variable Return on Asset  dan Return on Equity lebih kecil dari derajat kesalahan yaitu  0.938>0.05 untuk variable ROA dan 0.390>0.05 untuk variabel ROE Hasil penelitian secara simultan menggunakan uji f juga ditemukan bahwa Return on Asset dan Return on Equity tidak berpengaruh terhadap harga saham dikarenakan nilai signifikansi lebih besar dari derajat kesalahan yaitu 0,079 > 0.05.
Pengaruh Arus Kas Operasi, Nilai Buku Ekuitas dan Laba Akuntansi Terhadap Return Saham (Studi Kasus Pada Perusahaan LQ-45 di Bursa Efek Indonesia)
Authors: Tan Tan Kim Hek
Published: November 2022

Kebanyakan perusahaan menganggap bahwa laba bersih dalam laporan keuangan laba rugi sebagai indikator utama dari pemberian dividen kas. Namun, terkadang perusahaan dengan laba yang besar tidak mencerminkan jumlah kas atau likuiditas perusahaan. Hal ini menyebabkan perlu adanya informasi lebih lanjut mengenai keadaan likuditas perusahaan lewat informasi laporan keuangan arus kas operasi. Penelitian ini bertujuan untuk mengetahui Pengaruh Arus Kas Operasi, Nilai Buku Ekuitas dan Laba Akuntansi terhadap Return Saham (Studi Kasus Pada Perusahaan LQ-45 di Bursa Efek Indonesia). Penelitian ini dilakukan dengan menggunakan sampel berjumlah 17 perusahaan LQ-45 yang terdaftar di Bursa Efek Indonesia periode 2015-2019, dan data penelitian yang dianalisis berjumlah 85. Berdasarkan  Metode analisis data yang dilakukan dalam penelitian ini yaitu metode analisis regresi linear Hasil penelitian menunjukkan bahwa berdasarkan pengujian hipotesis menggunakan uji parsial, Arus Kas Operasi, Nilai Buku Ekuitas tidak berpengaruh terhadap Return Saham dan Laba Akuntansi berpengaruh terhadap Return Saham. Besarnya koefisien determinasi sebesar 0,141 artinya kemampuan variabel Arus Kas Operasi, Nilai Buku Ekuitas dan Laba Akuntansi secara bersama-sama dapat menjelaskan Return Saham sebesar 14,1%. Sedangkan sisanya 86,9% Return Saham dapat dijelaskan oleh variabel lain yang tidak dimasukkan kedalam penelitian ini. Berdasarkan pengujian hipotesis dengan menggunakan uji t dapat disimpulkan, bahwa Arus Kas Operasi, Nilai Buku Ekuitas tidak berpengaruh terhadap Return Saham dan Laba Akuntansi berpengaruh terhadap Return Saham sedangkan berdasarkan uji F disimpulkan bahwa Arus Kas Operasi, Nilai Buku Ekuitas dan Laba Akuntansi secara simultan berpengaruh terhadap Return Saham.
Viral Marketing, Celebrity Endorsement dan Brand Awareness Terhadap Keputusan Pembelian Pada Geprek Bensu Medan
Authors: Alfifto Alfifto , Siringoringo Anggelia , Hasman Haryaji Catur Putera
Published: November 2022

Penelitian ini bertujuan untuk mengetahui : (1) Pengaruh Viral Marketing terhadap Keputusan Pembelian Pada Geprek Bensu Medan. (2) Pengaruh Celebrity Endorsement terhadap Keputusan Pembelian Pada Geprek Bensu Medan. (3) Pengaruh Brand Awareness terhadap Keputusan Pembelian Pada Geprek Bensu Medan. Penelitian ini merupakan penelitian kuantitatif. Populasi seluruh konsumen yang membeli geprek bensu sejak tahun 2019-2021. Penelitian sampel dalam penelitian ini dilakukan dengan purposive sampling. Sampel yang diambil sebanyak 80 orang konsumen pada Geprek Bensu Medan. Teknik analisis data pada penelitian ini adalah analisis regresi linear berganda. Data penelitian bersumber dari kuesioner.

Viral Marketing berpengaruh positif dan signifikan terhadap Keputusan Pembelian pada Geprek Bensu Medan. Celebrity Endorsement berpengaruh positif namun tidak signifikan terhadap Keputusan Pembelian pada Geprek Bensu Medan. Brand Awareness berpengaruh positif dan signifikan terhadap Keputusan Pembelian pada Geprek Bensu Medan.
Case Report on CAKUT Syndrome with Known Case of Chronic Kidney Disease
Authors: Saloni Moon  , Kavita Gomase  , Shalini Moon  , Pradnya Sakale  , Roshan Umate
Published: November 2022

Background: Congenital abnormalities of the kidneys and urinary tracts (CAKUT) are conditions brought on by errors in the growth of the kidneys and the outflow tubes that drain the kidneys. Although the issue may not become apparent until later in life, CAKUT is a congenital abnormality brought on by improper urinary system development. Case presentation: We are presenting the case of a 23-year-old man who has chronic kidney disease and is undergoing maintenance hemodialysis. The patient was apparently alright 2 weeks back when he had complained of breathlessness. fever 2 episodes, lower which was insidious in onset and gradually progressive. On arrival, the patient was provided oxygen therapy via a face mask for breathlessness and to make him feel comfortable with the head elevation. On laboratory investigation, the patient’s blood values are altered. The patient underwent computed tomography of the kidney-ureter-bladder (CT-KUB), and Ultrasonography of the kidneys (USG). A permanent tunnel hemodialysis catheter under local anesthesia was placed and he received 2 cycles of hemodialysis. During the course in the hospital, the patient’s condition was improving and was stable clinically and vitally hence, the patient was discharged. Conclusion: CAKUT can occur alone or in conjunction with heart and cardiovascular malformations, gastrointestinal tract malformations, central nervous system malformations, skeletal system malformations, lung, face, genito-reproductive system malformations, abdominal wall malformations, chromosomal abnormalities, MCA, and other organ system malformations.
Baker’s Cyst in Left Popliteal Fossa: A Case Report
Authors: Sangita Shende  , Aparna kawale  , Priyanka meshram  , Sagar Alwadkar  , Aniket Pathade  , Pratiksha Munjewar
Published: November 2022

INTRODUCTION: A popliteal cyst, also called a Baker cyst, is a benign uncontrolled swelling of the gluteus medius sac in the popliteal fossa at the back of the knee described this excess fluid and subsequent sac formation outside of the kneecap in the commencement.A Baker's (popliteal) cyst is a swelling of the knee's gastrocnemius-semimembranous bursa, which connects to the back of the synovial membrane. It commonly presents as a painless swelling in the popliteal fossa. Adults almost always develop an edema as a result of pathological changes to the knee joint. Sometimes, the cyst enlarges to the position in which it ruptures, releasing synovial fluid into the surrounding tissues and present physiologically as acute thrombophlebitis. Popliteal cyst infection is a rare complication that is often related to septic arthritis. Popliteal joint cysts, also known to as Baker's cysts, are sporadically together with intra-articular knee conditions like osteoarthritis and dislocated patella. Anatomically, the borders of the cyst resemble synovial tissue, and there may be chronic, non-specific inflammation. Even if they are not visible in the knee joint, osteocartilaginous loose bodies may be present within the cyst.CLINICAL FINDING: Pain in the back of knee were the main complaints of a 48-year-old female admitted to Tertiary Rural Hospital.DIAGNOSTIC EVALUATION: Chest x-ray and blood test including all tests are done. Were all performed as part of the physical evaluation to prevent acute and chronic post-surgical discomfort following Excision of Bakers cyst.THERAPEUTIC INTERVENTION: Post operative treatment advised 6 hours iv fluids normal saline, ringer lactate 500ml, antacids, antiemetic, analgesic given frequently advised as the first line of treatment following excision of baker cyst . It gives superior pain relief and allows for a speedier recovery.OUTCOMES: Patient condition was poor.CONCLUSION: Baker cyst is a benign uncontrolled enlargement of the bursa in the popliteal fossa at the back of the knee that is diagnosed in the hospital on the IPD based on the patient having symptoms of swelling and pain in the back of knee. Based on a patient admitted to Tertiary Rural Hospital for diagnostic tests are done as per doctor order blood test, surgery of the excision of cyst . To reduce acute and chronic post-surgical pain after excision baker cyst. Post operative medications advised.
To study the effect of microbial contamination in semen and its effect on male infertility
Authors: Samiksha Kothare  , Akash More  , Ujwal Gajbe  , Deepti Shrivastava
Published: November 2022

According to the 3rd WHO methods, normal sperm morphology has been considered to be directly related with the fertilization process and pregnancy. The quality of semen such as sperm morphology, count, and motility has been reduced due to abnormalities in male thus, causing infertility. A considerable factor responsible for infertility among male partners may be as a result of microbial contamination. Semen may contain contamination while collecting sample. However, there are some sperm preparation techniques that can be used for the removal of contamination in semen such as; swim up, density gradient, simple wash, discontinuous density gradient. The main objective of this study is to find out the presence of infections and microbial contamination. This study will compare sperm count and sperm motility of patient’s semen sample with numbers of debris/ present infectious agent. Microbiological assay of semen sample will be performed. Also, various infectious agents causing infertility will be evaluated and studied. Semen analysis, semen preparation by density gradient, semen culture were carried out to look into the effect of microbial contamination on semen sample of infertile men.
SYNTHESIS CHARACTERISATION AND BIOLOGICAL EVALUATION OF BIS-CHALCONES BASED ON RESORCINOL
Authors: Haider Abbas Alwan  , Saadon Abdulla Aowda
Published: November 2022

The biogenetic antecedents of flavonoids and isoflavonoids, which are abundant in plants, are chalcones. They have antimitotic, antimutagenic, and antitumor-promoting properties, as well as antibacterial, antiviral, anti-inflammatory, and hepatoprotective properties.Claisen condensation of 1:2 moles of 2,4-Diacetyl Resorcinol (DAR) and substituted aldehydes yielded novel bis-chalcones, which were characterized by 1HNMR, and 13C NMR. To determine whether these compounds have antibacterial activity, the disk diffusion method was performed. Microorganisms are Gram-positive and Gram-negative.
Resilience and stress coping strategies of university students in times of pandemic
Authors: Hugo Condori Meléndez  , Mirtha Sussan Trejo de Rios  , Juan Carlos Lázaro Guillermo  , Lila Ramírez Zumaeta  , Carlos Alberto Giles Abarca
Published: November 2022

The objective is to determine if Resilience and stress coping strategies significantly influence each other in college students during the COVID-19 pandemic. A prospective and cross-sectional quantitative design study, 128 students from the National Intercultural University of the Amazon, Peru were selected: 96 men (75.0%) and 32 women (25.0%), mean age 18.3 years (SD = 2.3). The Adapted Resilience Scale of Peru (ERAPE) and the Coping Mode (COPE) were used. Resilience had a significant effect at a moderate level, and coping strategies focused on problems and emotions, with planning, active coping, and lack of emotional support dominating. Effects on proportional inverse correlation can be identified through avoidance strategies: mental and behavioral withdrawal, denial, and substance use.
DEVELOPMENT OF FUZZY INFERENCE SYSTEM FOR COVID-19 DATA ANALYSIS
Authors: Manisha Shinde-Pawar  , Jagadish Patil  , Alok Shah  , Prasanna Rasal
Published: November 2022

As COVID-19 Pandemic and related data is very recent. COVID-19 infected most of the population from entire globe with different impact. It disclosed the limitation of access of health and care resources. Various parameters like different symptoms, different existing health conditions, different age, diagnosis level and great uncertainties made the condition vaguer. Fuzzy can handle such vagueness and uncertainty of such voluminous data of patients and can support to medical stakeholders, experts, hospitals, pharmaceuticals etc. Fuzzy Logic is widely used to address so many uncertainties, incompleteness or imprecision. The current experiment implements Fuzzy Inference System for pattern identification and classification by applying fuzzy approach with Fuzzy Logic in R for performance improvement. This focuses on designing Fuzzy Rule base, Model and inference for COVID 19 data analysis.
INTERVENTION OF STUNTING AGED 0-59 MONTHS REVIEWING FROM NUTRITION
Authors: Indria Nuraini  , Retno Setyo Iswati  , Aisyah
Published: November 2022

Nutritional intervention is an effort to overcome nutritional problems with programs such as giving Fe and calcium tablets to pregnant women, giving zinc to children. To find out the factors that cause stunting and the effectiveness of Nutrition Interventions in Stunting Toddlers. This type of research is survey research with a cross-sectional design. The research sample was children aged 0-59 months with short or very short criteria, totaling 60 respondents. Sampling technique is purposive. Data analysis through Univariate and Multivariate. Univariate analysis to provide an overview of the prevalence of stunting in children aged 0-59 months and Multivariate Analysis to see the initial relationship of risk factors for stunting in children 0-59 months and the effectiveness of Nutrition Interventions for Stunting Toddlers. The analysis was performed by binary logistic regression. Of the risk factors for stunting found 5 factors that correlated with stunting, namely history of exclusive breastfeeding, p-value 0.007 <0.05 (OR 0.111, 95% CI 0.023 – 0.541), history of complementary feeding p-value 0.044 < 0, 05 (OR 0.297, 95% CI 0.091 – 0.970), the diversity of food content p-value 0.095 <0.10 and the odds ratio value of 2.743. Means that the diversity of food content consumed affects stunting by 2.743 times greater, nutritional adequacy p-value 0.042 <0.05 and odds ratio value of 3.429, meaning that nutritional adequacy affects stunting by 3,429 times greater and Immunity of toddlers with stunting p-value 0.029 <0.05 and OR 0.268, 95% CI 0.82 - 0.876. For the Nutrition Interventions studied in this study in the form of an intervention approach to pregnant women through supplementation of Fe tablets with a p-value of 0.02 <0.05 and an odds ratio of 0.194 and supplementary feeding obtained a p-value of 0.011 <0.05 and an odds ratio of 4.464. There is a significant relationship between the Nutritional Intervention of Fe tablet supplementation and feeding with stunting. History of complementary feeding, exclusive breastfeeding, nutritional adequacy, diversity of food content and immunity have an impact on stunting in toddlers. The main interventions that can be done to reduce stunting are by increasing good nutrition for pregnant and lactating women and conducting early intervention in cases of malnutrition by fulfilling a diet high in protein.
SIOFOR DRUG ANALYSIS FOR THE FORENSIC CHEMISTRY PRACTICE
Authors: Sultanova Adolat Aminboyevna  , Muxamedova Dilyora Shuxrat qizi
Published: November 2022

Siofor (metformin hydrochloride) is widely used to maintain weight in the second type of diabetes and as a complex treatment of obesity, as well as a slimming agent in biologically active supplements under various names. The presence of metformin hydrochloride with the strong effect of reducing sibutramine in Reduksin Forte capsules, taking it together with other disproportionate drugs causes an increase in cases of acute poisoning. In such cases, in order to provide quick medical assistance to patients, in order to obtain quick and accurate results in forensic chemistry practice, specific chemical toxicological analysis conditions are needed. The results of the analysis of Siofor (metformin hydrochloride) presented in this scientific article by thin layer chromatography and UV-spectrophotometry methods are closely related to forensic chemistry practice.
Synthesis, and biological activity of some new 1,3 – bis ( 4 – nitro benzyl -2 - aryl hydro pyrimidine
Authors: Aabd Alrazaaq Khazeal Nasih  , Khaled Fahd Ali
Published: November 2022

According to bright importance’s showed by pyrimidine and hydro pyrimidine derivatives a newly series of hydro pyrimidine derivatives was synthesized by three steps. The first step by synthesized bis Schiff base from reaction two equivalents of p-nitro benzaldehyde with one equivalent of 1,3-propane diamine (1,3-diaminopropane) to afford compound 1. The next step was to reduction the imine group by NaBH4 to afford compound 2. The finally step by cyclization compound 2 during reaction it with some arylaldehyde in constated acetic acid and refluxing the mixture for 24 to 72 hours to afford compounds 3a-h. The resulting compounds were characterized by FT-IR, 1H NMR, 13C NMR, moreover, their structures confirmed by elementary analysis (CHN). The antibacterial activity for newly synthesis compounds 3a-h screened using Staphylococcus aureus as Gram positive bacteria and Escherichia coli as Gram negative bacteria. Compounds 3a and 3h exhibited highest inhibition zone as well compounds 33 and 3g showed moderated antibacterial activity.
Historical Stages of Teaching Fine Arts in Schools of Uzbekistan
Authors: Botir B. Baymetov
Published: November 2022

The article provides information on the stages of development of Uzbek national visual art from ancient times to the present day. It contains information about various types and genres of fine art, great artists of the East, folk masters who created it. Also, the methodology of teaching fine art in Uzbekistan since the twentieth century, the pedagogues who worked in the initial stages of its development, the current teaching of fine art in general secondary educational institutions and higher education institutions, the development of the methodology are highlighted.
Effect of Gibberellic, Salicylic Acids, and NPK Fertilizers on growth and chemical constituents of Rosemary plants (Rosmarinus officinalis L.).
Authors: A W. N. Ali  , A. O. Al-atrakchii
Published: November 2022

This experiment conducted on rosemary plant (Rosmarinus officinalis L.), aimed to investigate the effect of gibberellic acid (GA3), salicylic acid (SA), and NPK fertilizer on growth and chemical constituents as well as determining the best concentration. After two weeks from planting the rooted cuttings in plastic pots were sprayed with the SA at three concentrations (0, 150 and 300 mg l-1), GA3 Sprayed with two concentrations (0, 400 mg l-1), and NPK sprayed as Nano NPK at concentrations (3 and 6 g l-1), the control plants were fertilized with regular fertilizer recommendation of NPK (200-N, 100-P, 50-K mg l-1). The results showed: The triple interaction among the three factors studied indicated that the plants which sprayed with 400 mg l-1 GA3, 300 mg l-1 SA, and 6 g l-1 nano NPK fertilizers gave the highest value number of branches 19.97 branch plant-1, volatile oil percent 1.626 %, and total chlorophyll content 32.70 mg g-1 f.w, whereas plant height increased to highest value at 400 mg l-1 GA3, 300 mg l-1 SA and 3 g l-1 nano NPK which reached to 38.30 cm, also production of volatile oil per plant increased at 400 mg l-1 GA3, 150 mg l-1 SA, and 6 g l-1 nano NPK fertilizers 0.947 ml plant-1. It appears that using those levels gave the best growth and development results on rosemary plant. Further research is needed to investigate whether the higher concentrations than used in this research will give the better parameters.
The Role of Perceived Sports Competence and Sport Anxiety in Determining Self-Talk in Elite Athletes
Authors: Gulcin SEZER HOCAOGLU  , Mehmet HOCAOGLU  , Ataman TUKENMEZ
Published: November 2022

The purpose of our research was to investigate the role of sport anxiety and perceived sports competence in determining the utilization of self-talk in elite athletes. Fifty six female (X̅age=24.62±3.40) and 65 male (X̅age=24.50±6.50); a total of 121 (X̅age=24.56±5.28) athletes who have at least three years of competitive experience and have previously represented Turkey with the national athlete title at international sports competitions were voluntarily participated in the study. Participants were given a personal information form along with the sports competence subscale of the physical self-description questionnaire which was developed by Marsh Richards, Johnson, Roche and Tremayne (1994) and adapted into Turkish by Marsh, Asci and Marco in 2002; the sport anxiety scale which was developed by Smith, Smoll, Cumming and Grossbard (2006) and adapted into Turkish by Akyol, Altintas, Sezer and Asci in 2016; the self-talk questionnaire which was developed by Zervas, Stavrou and Psychountaki (2007) for the purpose of determining athletes’ self-talk forms and was adapted into Turkish by Engur in 2011. After exploring a normally distributed data, the hierarchical regression analysis was used to determine the role of sports competence and sports anxiety in predicting the athletes' self-talk types. As a result of the research, statistically significant differences in both sports competence and self-talk usage levels were found between groups according to sport type and a statistically significant relationship was found in predicting motivational self-talk for both competition experience and sport type.
Health Related Fitness Physical Education Intervention: Self-Determination Perspective
Authors: Yasin Akinci  , Sadettin Kirazci
Published: November 2022

Introduction: The purpose of this study was to investigate the effect of 8-week health-related physical education (HRFPE) intervention on 9th-grade students' health-related fitness knowledge (HRFK) level, physical activity level (PAL), and physical fitness levels. Methods: Experimental research with two groups, HRFPE, and skill-based physical education, with 154 students, was measured before and after the intervention. While the experimental group attended the HRFPE intervention, the comparison group attended the skill-based physical education intervention. Quantitative data were gathered from Health-Related Fitness Knowledge Test (HRFKT), International Physical Activity Questionnaire for Adolescents (IPAQ-A), and Fitnessgram tests (Left & right leg Flexibility, Push-up, Pacer, Curl-up, and BMI). Data gathered from HRFKT, and IPAQ-A were analyzed by mixed-design multivariate analysis of variance (MANOVA). Data from Fitnessgram tests were analyzed by mixed-design analysis of variance (ANOVA). Results: The knowledge test results revealed a significant effect of HRFPE intervention on students' cardiorespiratory fitness, muscular endurance, training principles, and general health knowledge parameters of HRFKT. The intervention significantly increased the low and vigorous PAL of participants. The HRFPE intervention positively affected right leg flexibility, pacer cardiovascular, curl-up muscular endurance, and BMI. Results demonstrated the effect of self-determination theory based HRFPE intervention on developing students' HRFK level, physical activity behavior, and physical fitness test performances. Conclusions: This study revealed that physical education teachers could design and implement HRFPE course interventions in real school settings. Further recommendations were discussed regarding the content and implementation of intervention for physical education teachers, curriculum specialists, and future studies.
Alopecia areata: The disease of hairless patches on the scalp and any area of face
Authors: Sakshi Patel  , Yashica Rawal  , Pragnesh Patani
Published: November 2022

Up to 2% of the population is affected with alopecia areata (AA), a prevalent chronic tissue-specific autoimmune disease that causes hair loss. The specific pathobiology of AA is still unknown, however the most widely accepted idea is that an immunological process led the hair follicle's immune privilege to collapse. The etiology of AA is influenced by numerous environmental and genetic variables. One or more well-defined patches, more diffuse or total hair loss of the scalp (alopecia totalis), or hair loss of the entire body are all clinically treated for AA using a variety of clinical approaches (alopecia universalis). Corticosteroids and other immunomodulators, minoxidil, and contact immunotherapy are some of the available treatments for AA.
Comparative Analysis Of Chemical Constituent And Antimicrobial Potential Of Acorus Calamus Linn (Sweet Flag) In The Different Geographical Regions Of North Himalayas
Authors: S. P. Bhatt  , Kiran Dobhal  , Amit Semwal  , Sanjay Rao  , Ranjan Kumar Singh  , Jaya Rautela  , Mansi Butola  , Bhawna Kapoor
Published: November 2022

Sweet flag (Acorus calamus) is a well-known plant all over the world due to its specific bioactive components β- asarone in plants.The present study reports the quantitative estimation of rhizome oil of the sweet flag plant; obtain from the various district ofUttarakhand, and different geographical surroundings. GC-MS is used to estimate the quantity of rhizome oil. Although leaves areenriched by the several medicinal constituents revealed by the previous studies, rhizome, and the oil it is being investigated. The maincomponent which was identified was Cis-ocimene, Linalool, Trans methyl isoeugenol, β and α-asarone, and euasarone. β-asarone inthe different samples; showed a higher percentage as compared to another component. It was observed that the Gopeshwar regionsample had the 74.36 least percentage and the Pauri sample had the 92.22 highest percentage of β-Asarone. Meanwhile, the Gopeshwarregion sample had 17.25 highest percentage, and the Pauri sample had 1.57 least percentage of α-Asarone. Fungal infection is prevalentnowadays. The oil from all regions subjected to antifungal activity against the Aspirigilla fumigates, A. Parasiticus, MicrosporumCanis, M. gypsum, Cladosporium, Aspergillus niger. The inhibition zone diameter (IZD) against Aspirigilla fumigates, A. parasiticusand was a maximum of 10cm for the Gopeshwar sample,9cm for the Ramnagar sample as compared to the reference drug gentamicin.
Effect Of Aromatic Oil Of Three Plants Of Labiatae Gene On Microorganism By Using In Preservation Of Minced Meat
Authors: Majeed M.Abid  , Talib Kh. Hussain  , Emad Hamid Hwaidi  , Hawraa I. Kadhim
Published: November 2022

The effect of oil extracts of three plants of Labiatae gene, Mentha longifolia, M. spicata and Ocimum basilicum, by the agar well diffusion method, were studied, the total count of the bacteria responsible for spoilage meat was kept at 4-6˚C for different periods (1, 72,192) hours. The results showed that the oils extract were inhibited all the treatment that were studied and more affected inhibition of the growth of Staphylococcus aureus than the growth of other microbes. The total count of the bacteria responsible for meat spoilage decrease in all treatments extracted oils for all different periods. Statistic analysis results showed high significant variations at the level P≤ 0.01 of all the treatment and control for all reservation periods.
Treatment of Unstable Thoracolumbar Burst Fractures with Single-Stage Posterior Subtotal Corpectomy and Circumferential Reconstruction: A Prospective Observational Study in Jammu
Authors: Dr Naresh Rana  , Dr Gagandeep Singh  , Dr Rishabh Gupta
Published: November 2022

Background: The term thoracolumbar fracture essentially refers to the fact that the bone is broken in the thoracic (middle) or lumbar (lower back) region of the spine. The present prospective study has been objectively conducted to evaluate the clinical and radiological outcome of single stage subtotal corpectomy and circumferential reconstruction of unstable thoracolumbar burst fracture. Methods: This prospective study was carried out in GMC Jammu from October 2017 to December 2018. A total 20 patients with acute traumatic unstable burst fractures at thoracolumbar junctions were included in this prospective study who qualified the defined inclusion criteria.Results: The mean sagittal plane kyphosis pre operatively was 24.845.220 which reduced to 13.155.30at post-operative day 1. At final follow up, sagittal plane kyphosis was 15.105.650. The mean Anterior Body Compression was 33.646.79% which decreased to 22.3 % at post-operative day 1. At final follow up, mean ABC was 24.264.95%. VAS score reduced from mean value of 6.85 to 2.2 at final follow up which is slightly less compared to what others reported. Conclusion: The present study revealed that indirect decompression and posterior subtotal corpectomy and circumferential reconstruction fulfill all the aims of surgical treatment of fractures and fracture dislocations of thoracolumbar spine. We recommend longer follow up to assess the degree of correction of kyphosis and re-collapse and neural recovery with single stage posterior subtotal corpectomy and circumferential reconstruction
Formulation Development and Evaluation of Herbal Nanoparticles containing Ointment of Leaves extract of Rhynchosia rothii
Authors: Sharad D. Tayade  , Narendra Silawat  , Neetesh Jain
Published: November 2022

In our previous work we have reported wound healing activity of leaves extract of Rhynchosia rothii in which we got excellentactivity. Therefore in present study, the development of Rhynchosia rothii loaded Lycoat RS 720-BSA conjugated polymericnanoparticles and subsequent ointment formulation has been aimed. Maillard Reaction was used to develop the Lycoat RS 720-BSAconjugate. The solvent evaporation approach was used to produce nanoparticles with Rhynchosia rothii loaded on them. Thenanoparticles had a 257nm particle size and exhibited a spherical shape. The zeta potential in the formulation was -22.4 mV.Entrapment efficiency was 88.32% in the enhanced batch. The extracted content of the optimized batch was found to be 78.10%. Acontinuous release pattern was found by the in-vitro diffusion investigation, with 94.24% diffusion after 24 hours. The Rhynchosiarothii extract was created as an absorbent ointment formulation with a pH of 6.80–6.92 and a spread ability of 80.00–110.16 g.cm/s.It also has a distinctive aroma. Ointment containing herbal nanoparticles from the F4 batch has produced positive results. A newmethod of promoting nanoparticles in herbal medication delivery systems is by employing them in nanoparticles and an ointment.From present investigations we concluded that prepared ointment can be used clinically for the treatment of wounds if optimizedfurther using more in vitro and in vivo models along with toxicity predictions.
Synthesis, Characterization, Molecular Docking and Biological studies on Novel Pyazole fused Indole Derivatives
Authors: Padmaja V  , M. Sumakanth  , P.Shashikala
Published: November 2022

The present work deals with the sequence of Novel Pyrazole fused Indole derivatives(4a-4l) were synthesized by simple conventional method andscreened for anthelmintic, antibacterial and anticancer activities. The molecular docking studies were also performed. All of the newly synthesizedcompounds were structurally characterized on the basis of IR, 1HNMR and Mass spectral analysis. Further, all of the newly prepared pyrazole fusedindole derivatives were screened for anthelmintic activity by using Albendazole as standard drug. The antibacterial activity was carried out by agardiffusion (Cup plate) method by using Streptomycin as standard and anticancer activity against MCF-7 cell lines by MTT assay method. The resultsshowed that some of the compounds 4b, 4c and 4f exhibited good anticancer activity. The compounds 4c, 4f, 4j showed good anthelmintic activity and4b,4h and 4i exhibited potential antibacterial activity by comparing with standard drug. Additionally, the molecular docking studies of novel pyrazolefused Indole derivatives was also carried out to explain putative bonding interaction between the active site of EGFR enzyme and synthesized NovelPyrazole fused Indole derivatives by Schrodinger suite.
A Simple And Validated Spectrophotometric Analysis Method For The Hydrophobic Drug Fenofibrate In Natural Oils
Authors: Hayder Jaafar Sadeq  , Mowafaq M. Ghareeb
Published: November 2022

Objective: In this work, sodium lauryl sulfate (SLS) was used to present a simple spectrophotometry approach to more accuratequantification of fenofibrate (FENO) concentration in five natural oils (soybean oil, lemon oil, black seed oil, cardamom oil, and garlicoil). In the published work either organic solvent was used which may result in false results due to the dissolving of oil by organicsolvent, or high-performance liquid chromatography (HPLC) was utilized, which is a sophisticated instrument that may not be availableat every research facility.Methods: construction of a calibration curve using a series of FENO concentrations added to 0.5% SLS phosphate buffer solution andmeasuring the absorbance by spectroscopy at 289 nm. The drug samples in different oils were diluted with 0.5% SLS phosphate buffersolution prior to direct reading by spectroscopy. According to the International Conference on Harmonization requirements, the methodwas validated regarding specificity, precision, accuracy, and determination range.Results: FENO gave absorbance maxima at 289 nm in 0.5% SLS solution, the beer’s law was obeyed in the range of 0.0125 to 0.05mg/ml. High linearity (in the scope of 10 - 125 mg, R2=1), highly specific, good accuracy (95- 104), precision (SD< 10%), and a widerange of detection, indicate validation of the procedure.Conclusion: the proposed method for FENO analysis is simple, fast, and promising for easy determination of FENO in bulk andpharmaceuticals.
Assessment Of Biofilm Production Of Obligatory Aerobic And Anaerobic Bacteria For Acne Patients In Kirkuk – Iraq
Authors: Noor raad soady  , Asma Sumiea Karomi
Published: November 2022

The study which involved 200 patients with Acne vulgaris, was carried out in Kirkuk City from October 2021 to March 2022. Toestablish the bacterial species that create a biofilm and to isolate and identify the bacterial species that causes Acne vulgaris patients.Acne swab were obtained for aerobic and anaerobic culture, microtiter plate method (MPA), and congo red agar (CRA), methods wereused to detect the biofilm formation.Propionibacterium acnes plays a role in the pathogenesis of acne vulgaris, a common disorder of the pilosebaceous follicles and it hasbeen suggested that P. acnes cells residing within the follicles grow as a biofilm.The most common isolated bacteria P.acne 40.5%, followed by S.epidermidis 22.5%, S.aureus 19.5%, and 7% S.pyogenes . The resultsof the current study indicate that type of bactera isolates were strong biofilm producer by microtiter plate method (MPA) and congored agar method , 88.9% of P.acne,73.3% of S. epidermidis , 64.1% of S. aureus , and 70% of S.pyogenes , isolates were strongbiofilm producer by MPA, while the results also showed the74.0% of P.acne ,73.3% of S. epidermidis , 71.7% of S. aureus ,70% ofS.pyogenes isolates were strong biofilm producer by CRA
Synthesis And Characterization Of New Styrenated Alkyd Resin From Olive Oil As Binder For Surface Coating
Authors: Ruaa Jameel Kamel  , Farah Safi Khliwi  , Ammar Ali Hussein  , Karrar hazim Salem  , Mohamed Ali Mutar
Published: November 2022

In the current review article, an effort has been made to emphasize the inner workings of alkyd resins, the earliest polymeric resincreated from vegetable oils, in light of technological advancements that have occasionally been made to increase their practical utility.The thorough synthesis and use of several kinds of water-born alkyds were explained in order to lessen the use of organic solvents. Tocreate one set of styrenated alkyds, the Styrene monomer was used to post-polymerize the alkyd at 5:5 ratio at 80 °C for 6 hours. 1Standard techniques were used to define and assess the styrenated alkyds' physical and chemical characteristics, drying time, andchemical resistance. Each resin displayed favorable characteristics. Even without a dryer, the styrenated alkyds provided a quickerdrying time2. The styrenated alkyds were resistant to alkali, in contrast to the unstyrenated alkyd, which is just resistant to conditionsthat are acidic, wet, or briny. The AAST's coatings The FTIR, HNMR, DSC, and TGA methods were used to confirm the structures ofthe changed resins that were obtained. The findings of the physico-mechanical tests demonstrated that the styrenated alkyds that wereproduced are suitable for a range of coating applications.
“Assessment Of Human Root Dentin's Fracture Resistance To Intra-Canal Calcium Hydroxide, Mineral Trioxide Aggregate, And Calcium Phosphate Cement”.
Authors: Dr Akhilesh Singh Parate  , Dr. Pauravi Hegde  , Dr Surabhi Duggal  , DR. ASHTHA ARYA  , Dr. Pawan Anil Pawar  , Dr. Ratheesh M.  S
Published: November 2022

Background: The use of Ca(OH)2 in Endodontics was undisputed till date. Amidst its various merits, recently it has been observed that Ca(OH)2 treated teeth for extended periods show high failure rate because of unusual preponderance to root fracture. Newer materials like MTA and CPC have shown promising results in multiple endodontic applications including apexification. Objective: The aim of the present study is to compare the in vitro changes in the fracture resistance of human root dentin when exposed to intracanal Ca(OH)2 , MTA and CPC. Methodology: 60 freshly extracted single rooted teeth were selected and divided into four following groups of 14 teeth each Group I –saline group (control group) Group II - Ca(OH)2 group Group III – MTA group Group IV – CPC group Coronal access and endodontic instrumentation was done using specified instruments and techniques. The prepared canal was filled with saline solution, Ca(OH)2 paste, MTA and CPC and sealed with bonded composite resin and teeth were immersed in saline. After 30 days and 180 days the roots of 7 teeth from each group were sectioned horizontally into 1mm thick disks depending upon length of root into 4-5 sections and each disk was placed under a universal testing machine and the peak load at fracture was recorded.Results: Results showed that the mean peak load at fracture of Group I (saline group) was higher in both 30 days and 180 days specimen. Ca(OH)2 group showed a decrease in the fracture resistance as compared to all other groups in 30 and 180 day specimen.Conclusion and Interpretation: Based on results, both MTA and CPC can be efficiently used as an alternative to Ca(OH)2.
A Study To Assess Desarda Vs Lichtenstein Technique For The Treatment Of Primary Inguinal Hernia
Authors: Dr. Sagar Shyamsunder Paliwal  , Dr. Aakash Katkar  , Dr Nitin Nangare
Published: November 2022

Background: The present study was conducted for assessing and comparing the efficacy of Desarda vs Lichtenstein technique for thetreatment of primary inguinal hernia.Materials & Methods: 100 patients scheduled to undergo treatment for inguinal hernia were enrolled. Complete demographic andclinical details of all the patients was obtained. All the patients were randomized into two study groups: Group A (50 patients)-undergoing treatment by Desarda technique, and Group B (50 patients)- undergoing treatment by Lichtenstein technique. Forperforming Lichtenstein tension-free mesh repair, a polypropylene mesh was trimmed to fit the inguinal floor. Chronic pain wasassessed on a VAS score of 0 to 10 with 7 to 10 indicating strong pain while 3 to 6 indicating moderate pain. All the results weresubjected to statistical analysis using SPSS software.Results: Group A and group B subjects took 15.3 days and 14.2 days respectively for returning to basic activity. Group A and groupB subjects took 5.1 days and 8.3 days respectively for returning to home activity (p- value < 0.05). Mean hospital stay was 3.2 daysand 2.9 days among subjects of group A and group B respectively. Foreign body sensation was felt in one patient each of both thestudy groups. Incidence of seroma formation was higher among the patients of group B in comparison to patients of group A. Meanoperative time was significantly lower among patients of group A.Conclusion: Outcome is better for Desarda technique in comparison to Lichtenstein technique for the treatment of primary inguinalhernia.
Systematic Review On Covid Vaccination In Children- Assessment Of Safety, Immunogenicity, Efficacy And Adverse Effects
Authors: Dr Amandeep Kaur  , Dr Navdeep Kaur  , Dr Preeti Singh Dhoat  , Dr Mohit Madhukar
Published: November 2022

Introduction: The recent pandemic outbreak Covid-19 has led to substantial illness and ultimate mortality across the globe and childrenare highly are in the verge of being in a critical role as vectors in the transmission of SARS-CoV-2 in the community. There are quitea few studies which have observed that the vaccinated individuals who become infected again are on the side fewer side to transmit thevirus due to reduced viral load and the duration of virus shedding and as a result, transmission from vaccinated individual to householdcontacts is significantly lower. This systemic review was thus undertaken with the objective of analysing the literature that wereavailable on the safety, immunogenicity, efficacy and if any adverse effects of covid vaccination in children.Material and Methods: We conducted both a systematic review. This review was solely based on the predefined protocol and it wasconducted in concordance with PRISMA guidelines.Conclusion: The available data reports similar efficacy and safety in children as of adults. Therefore, more clinical trials are needed tobe conducted and published for evaluation of safety and if any long-term effects of Covid vaccines.
A Study Of Sociodemographic Profile Of The Patients Undergoing Hip Joint Replacement In A Tertiary Hospital In Central India
Authors: Kunal Saoji  , Suvarn Gupta  , Ashwin Chavan  , Vasant Gawande  , Siddharth Jain
Published: November 2022

Hip arthroplasty made a revolution the field of orthopedics as the earlier thought of painful conditions like osteoarthritis or rheumatoid arthritis could now be solved by replacing the damaged joint with an artificial joint which dramatically improves the pain of the patient and the person who could barely walk due to pain starts walking again pain free. This magical medical innovation has changed lives of many worldwide. As the mean life span of the population is increasing, the diseases attributed to the age like osteoarthritis is also increasing and hence the scope for joint replacement is boundless.This study was an observational study to study the socio-demographic profile of the patients undergoing hip replacement arthroplasty in a tertiary hospital in central India.Methodology: This study was a record based observational study conducted retrospectively in the department of Orthopaedics in a tertiary care hospital in central India from 1st May 2021 to 30th April 2022. Sample Size of 50 patients were analyzed and pat clinical data was used from hospital records.Observation And Results: A total of 50 patients were studied in total. Out of them 30 were males and 20 were females. The mean age of the patients was 60.2 years. Out of the 50, 20 patients had yellow ration card i.e. belonging to lower socio economic status while 20 had saffron ration card and only 10 had white ration card. Majority of the population was Hindu (40%) followed by Muslims (30%), Buddhist (24%) and 6% were Christians, Sikhs and Jains. Majority of the population was educated up to 10th standard while 16% were illiterate. Osteoarthritis was the most common indication for hip joint replacement (70%).Conclusion: Due to better schemes for the poor, facilities, and equipment and the will to serve the poor, old age poor people can also get costly operations like hip joint replacement done to alleviate them from their sufferings.