bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of organofluorine compounds on the body of workers in industrial conditions
Authors: Khamitova R. Ya. , Titenok L. N. , Shaisultanova G. I. , Zadorova E. G.
Published: March 2022

Organofluorine compounds, despite the constant expansion of their applications and the synthesis of new drugs, remain poorly understood. At the shop where the technological process is carried out according to the closed type, the leading unfavorable factor is the pollution of the working area air with trifluoropropylmethyldichlorosilane.

Analyzing sickness rate with temporary work disability of the workers of this production we paid attention to higher indexes of cases and days of disability per 100 workers (80 cases and 688 days) than in the control group (66 cases and 562 days) numbering 111 people (employees of accounting, computer center) selected by the method "copy-pair" by age. In addition, we also noted cases of allergic diseases in the apparatus workers of the workshop.
Criteria for Evaluation of Hemodynamic Status and Physical Tolerance in Postinfarction Cardiosclerosis
Authors: Komissarov V. A.
Published: March 2022

Exercise tolerance in patients with coronary heart disease with postinfarction cardiosclerosis is determined by the level of coronary and myocardial reserve. At the same time, the larger the surface of the infarcted area and the number of coronary arteries affected by atherosclerosis, the lower the exercise tolerance. The presence of close correlation between heart size and the degree of coronary insufficiency, the size of postinfarction scar, its localization, the level of end-diastolic pressure in the left ventricle prompted us to check the diagnostic significance of the most informative X-ray cardiometry parameters for postinfarction cardiosclerosis patients in the assessment of the functional state of the circulatory system and the possibility to predict physical performance without ergometric study.
Differential diagnosis of rheumatic mitral stenosis by m-echocardiography
Authors: Marhasina I. P.
Published: March 2022

Since the first steps of echocardiography, reduction of diastolic opening of the mitral valve has been one of the main signs of rheumatic mitral stenosis, but meanwhile this fact documents only mitral blood flow limitation, which can occur not only at valve, but also at supravalvular and subvalvular levels and has nothing to do with rheumatic etiology of valve lesion. This article is devoted to the discussion of these controversial issues and the role of M echocardiography in the differential diagnosis of rheumatic valve lesion.
Use of 99Tc-diphosphonate scintigraphy in the diagnosis of arthritis
Authors: Yunusov R. V. , Gabitov S. Z. , Tagirov I. S.
Published: March 2022

Early diagnosis of arthritis is a challenge for clinicians because clinical signs, biochemical and immunological studies are not specific enough, and radiography reveals changes in bone tissue only in the unfolding clinical picture of the disease. Therefore, radioisotope diagnostics of bone and joint diseases with pyro-monodiphosphonate or methylene diphosphonate labeled with 99Tc is becoming more widespread.
Impaired platelet haemostasis in patients with myelodysplastic syndrome
Authors: Shitikova A. S. , Belyazo O. E. , Ushakova E. A. , Kuraleva V. V.
Published: March 2022

One third of patients with myelodysplastic syndrome die before the development of leukemia from infectious and hemorrhagic complications; after the onset of acute myeloleukemia this figure reaches 59%. Therefore, the relevance of studying hemostatic disorders in preleukemic conditions is dictated primarily by the need to preserve the lives of patients. Literature data indicate the absence of significant changes in the plasma-coagulation component of hemostasis and fibrinolytic processes. At the same time, hematopoietic dysfunction in myelodysplastic syndrome necessarily includes megakaryocytic bone marrow, which cannot but affect the functional state of the platelet apparatus, the assessment of which was the main task of this work.
Effect of short-term oxygen inhalation on hemodynamics and ventilation in pulmonary tuberculosis patients
Authors: Vizel A. A.
Published: March 2022

Among all methods of treatment of chronic respiratory diseases only long-term oxygen therapy can prolong patient's life, while the effect of drugs on the survival rate of this group of patients has not yet been proven. Favorable effect was also noted in pulmonary tuberculosis. Since most mechanisms of the influence of oxygen on the body have been studied in nonspecific chronic respiratory diseases, it seemed relevant to investigate these mechanisms in pulmonary tuberculosis and compare the results with relevant data in the literature.
On the tactics for catarrhal appendicitis
Authors: Yudin Ya. B. , Babinskiy S. A.
Published: March 2022

The issues of diagnostics and treatment of acute appendicitis are systematically covered in the periodical press, but insufficient attention is paid to the tactics of non-destructive (catarrhal) form of appendicitis, the causes of rather frequent removal of morphologically unchanged processes in patients with the clinical picture of acute appendicitis and measures to reduce the number of needless appendectomies.

Some authors consider appendectomy mandatory in all cases of pain syndrome in the right iliac region. Thus, according to S.D. Lebedev, appendectomy is performed in 84.4% of patients admitted with suspected appendicitis. The unchanged appendectomies, which, in the author's opinion, contribute to the reduction of appendicitis morbidity.
Disruption of neuroendocrine status due to marriage
Authors: Kozlov L. A. , Yeremkina V. I. , Badzhelidze I. G.
Published: March 2022

Menstrual dysfunction in women of reproductive age is a frequent pathology that leads to infertility. Endocrinological infertility has a significant specific weight among other forms of disorders of generative function, its frequency reaches 35-40%. A special group of patients with primary infertility are women who have just married. It is noticed that the beginning of sexual life is not indifferent to the young body: in some people with the beginning of sexual life menstruation became less frequent and as a result a persistent amenorrhea was established. No endocrinological disorders were clinically detected.
Lethality of Patients with Combined Craniocerebral Trauma
Authors: Krylov V. E. , Andreev P. S. , Safronova S. N. , Zainullin R. V.
Published: March 2022

The aim of the present study was to identify the main errors in diagnosis, peculiarities of localization of injuries, and causes of death of victims with combined craniocerebral trauma depending on their age.
A rare case of osteogenic contracture of the mandible
Authors: Suleimanov A. M. , Shestakov Yu. N. , Kozlov V. N.
Published: March 2022

We observed one patient who developed bone contracture of the lower jaw after 3 years due to contusion of the left parotid chewing area. Here is an excerpt from his medical history.
Using liposomes to administer Terrilithin
Authors: Kovaleva T. N. , Kobrinsky G. D.
Published: March 2022

Among the various ways of introducing drugs into the patient's body, the easiest and most convenient is their ingestion. However, this method is acceptable only when the molecules of the administered substances are not degraded by digestive enzymes. This is especially true for drugs of protein nature, which are degraded by various proteolytic enzymes. It is therefore not surprising to see numerous attempts to shield ingested substances from biodegradation in the digestive tract. The easiest way to solve this issue would be to use some kind of carrier. The search led researchers to liposomes - phospholipid vesicles capable of containing other substances.
Treatment of isolated and combined forms of exudative frontitis
Authors: Yagudin K. F.
Published: March 2022

The problem of exudative frontitis treatment is still relevant. Among a number of methods of their treatment, the restoration of the drainage and ventilation function of the fronto-nasal canal is of leading importance, since the timeliness of exudate evacuation from the sinus depends on its permeability.
The value of prostatic acid phosphatase in the differential diagnosis and treatment monitoring of prostate cancer
Authors: Shakhov E. V. , Svetozarskiy N. L. , Klochikhin O. Z. , Salmin A. A.
Published: March 2022

One of the numerous tumor markers used in the clinic in the diagnosis of prostate cancer is the determination of the activity of prostatic acid phosphatase in the blood serum. This indicator has been used in the clinic since the 30s, but its role in the diagnosis of prostate cancer remains controversial. Some authors consider the activity of prostatic acid phosphatase to be an especially sensitive test in the diagnostics of this disease, while others, on the contrary, point out its low level of informativeness.
Clinical features and treatment of chronic bronchitis in elderly patients with tuberculosis
Authors: Trofimova R. I.
Published: March 2022

The peculiarity of modern pathomorphosis of pulmonary tuberculosis is its high frequency of combination with chronic bronchitis, which, according to different authors, is from 23 to 93%. The prognosis of chronic bronchitis worsens considerably if it is complicated by bronchoobstructive syndrome. It is known that impairment of bronchial patency can be caused by various pathophysiological mechanisms: spasm of bronchial smooth muscle, bronchial glands discrinism, obstruction of bronchial drainage.
Restorative treatment of patients with ovarian endometriosis
Authors: Sabsay M. I.
Published: March 2022

Reconstructive treatment of patients with ovarian endometriosis is most often performed by the doctor in the postoperative period. The peculiarity of this frequently occurring variety of ovarian tumor-like masses is the extreme polysymptomatic nature of the clinic. The cyclical nature of the manifestations, characteristic of endometriosis, is also seen in ovarian lesions, but both the painful symptom and menstrual function are significantly influenced by a pronounced adhesion process in the pelvis. This circumstance explains the comparative rarity of preoperative diagnosis of ovarian endometriosis - it varies about 7%.
Heliometeorological forecast and traumatism
Authors: Altunin V. F. , Halfiev N. G. , Lerner P. I.
Published: March 2022

We tried to establish the relationship between unfavorable heliometeorological prognosis and traumatism.We analyzed data on the admission department of the Kazan branch of the All-Russian Scientific Center "Restorative Traumatology and Orthopedics" for 12 months (from March 1987 to February 1988). The patients were admitted 2 times a week (Friday and Sunday) for two kinds of injuries: locomotor system and craniocerebral trauma. In total, during 106 days of medical care 4134 people sought medical help, we took the heliometeorological forecast according to the data of the weather service of Kazan. The most saturated magnetic storms were March and May, the least - September and January.
Dental caries incidence in children due to different fluoride content in drinking water
Authors: Eldarusheva Z. A.
Published: March 2022

We studied the prevalence and intensity of dental caries among children in the cities of Makhachkala and Kazan, which differ in the content of fluoride in drinking water.

The frequency of dental caries was determined in 617 children (in Makhachkala - 332 children, in Kazan - 285) aged 5-8 years. All children were divided into 4 age groups. Caries lesion intensity was established by calculating the CP index for deciduous teeth, CPU and CP - for a changeable bite. Caries prevalence was expressed as a percentage of the total number of examined children.
Menstrual function in the long term after induced termination of pregnancy in the first trimester
Authors: Bakuleva L. P. , Gatina G. A. , Kuzmina T. I.
Published: March 2022

The purpose of this study was to investigate the state of menstrual function in the remote period after induced termination of pregnancy in the first trimester.
Scleropolycystic ovaries in combination with a small form of ovarian endometriosis
Authors: Volkov E. A.
Published: March 2022

The problems of ovarian scleropolycystosis and endometriosis are still very topical. This is evidenced by the literature data of recent years and, in particular, by the proceedings of the VI All-Russian Congress of Obstetricians-Gynecologists (1987). However, among the many publications devoted to these two forms of the disease, we have not encountered works describing their combination, rather rare in the clinic. It is known that endometriosis is characterized by changes in menstrual function by the type of algomenorrhagia with autonomic symptoms in contrast to ovarian scleropolyckystosis, which manifests as hypomenstrual syndrome and virilization. We observed a combination of these two diseases.
Osteoma of the external auditory canal
Authors: Bobrov V. M.
Published: March 2022

Osteomas of the external auditory canal are quite rare. Their etiology is unknown. Many authors consider osteomas of the external auditory canal in particular as a further development of exostosis. Osteomas themselves do not bother the patient as long as they do not give rise to growth, in which the lumen of the external auditory canal decreases. In such cases, patients complain of decreased hearing, noise in the ear, and heaviness in the head.
Hygienic characteristics of atmospheric air pollution and health status of children living in rural experimental settlements
Authors: Dautov F. F. , Mukhamedshina R. I.
Published: March 2022

Industrialization and intensification of the economy, increased capacity of livestock complexes, high rates of urbanization can lead to environmental pollution, which, in turn, affects the sanitary living conditions and human health.The aim of our research was the hygienic characterization of atmospheric air pollution at different distances from livestock complexes and block outbuildings with an assessment of its impact on the health of the child population. Since the solution of environmental problems is carried out both at the stage of drawing up projects (schemes) of district planning and during the planning of rural settlements, at the first stage of the work we studied the construction projects of the settlements. We determined the pollution of atmospheric air with formaldehyde, hydrogen sulfide and ammonia. The work also used sociological methods - interview and questionnaire survey of the population.
Assessment of knowledge of breast self-examination techniques by women
Authors: Kuznetsova T. I. , Kuznetsov I. V.
Published: March 2022

Incidence of malignant neoplasms of breast for the last 15 years has increased more than twice and has a tendency for further growth. The efficiency of breast cancer treatment depends first of all on the timely diagnostics because the results of its therapy are mainly determined by the degree of spread of tumor process. Among the methods of active detection of the breast cancer the method of self-examination proved to be the most effective, which is given the highest priority in the WHO oncological program.
Substance abuse by adolescents with criminal behavior
Authors: Valeeva A. M. , Sibgatullin Zh. Zh.
Published: March 2022

In recent decades, there has been a tendency toward a significant increase in alcoholism, drug addiction, and substance abuse among adolescents and young adults. Much work is currently being done to study the specifics of the clinical manifestations of drug and substance abuse in adolescence, and a system of treatment and preventive measures is being developed.
Socio-psychological aspects of the problem of alcoholism
Authors: Knyazeva T. M. , Klassen I. A.
Published: March 2022

During the last decades a great number of clinical, psychological and socio-psychological publications have appeared which consider not only the personal features of patients with alcoholism, but also the influence of some or other environmental factors on alcoholism formation, its course and therapy. V. N. Tikhonov and D. Y. Donskoi, in their examination of 437 patients with alcoholism, revealed the influence of production factors on the development of alcoholism. I.D. Muratova and P.I. Sidorov identified as "threatened contingents" among adolescents those with asocial forms of behavior, those brought up in an incomplete family or in a family with alcoholics, with pedagogical or social neglect, asocial company, idleness of behavior, one-sidedness of hobbies etc. A number of studies have pointed to a certain role of conflict factors in the emergence of alcoholism in the family.
The Experience of Clinical Residents of the Medical Institute with Workers on the Shop Floor
Authors: Galiullin A. N. , Abdyushev Sh. Ya. , Ivanicheva N. A.
Published: March 2022

The problem of clinical examination has set a number of tasks for medical universities, among which the most important should be considered the training of highly qualified specialists, strengthening the material and technical base of teaching, the introduction of scientific achievements into practice, as well as the direct participation of institute employees in the medical examination of the population, especially workers of industrial enterprises.
The place of reflexology in the general population medical examination
Authors: Ivanichev G. A. , Shakurov R. Sh. , Pinyagina I. N. , Semyonova N. A. , Yakupova R. G. , Shageeva L. K. , Bilalova A. Sh.
Published: March 2022

During mass prophylactic investigations, detection of various disorders, especially visceral ones, nowadays requires time-consuming and expensive investigations using scarce equipment and reagents; besides, numerous highly qualified personnel are needed. Therefore, the development of informative, technically simple and quickly achievable methods of express diagnostics is one of the important tasks of practical medicine. For these purposes auricular diagnostics has been recently applied abroad and in our country. It is believed, that functional and organic lesions of different internal organs and systems are accompanied by changes in corresponding auricular zones and points.
Experience and scope of staged treatment of otorhinolaryngological diseases of workers engaged in the production of mineral fertilizers
Authors: Bikbaeva A. I. , Arefieva N. A. , Lisnyansky E. Z. , Tsyglin A. A. , Smirnov A. A.
Published: March 2022

In the process of producing nitro- and diammophoska, phosphoric acid and feed precipitate, the main harmful factors affecting the human body are acids and oxides of phosphorus, nitrogen, potassium, calcium, fluorine. They are in the air in the form of dust and vapor, and their concentrations can exceed the maximum allowable. In addition, the negative impact of powerful industrial noise is known. Reduction of local and general immunological reactivity of the body under the influence of chemical agents can lead to respiratory tract diseases. Industrial noise causes changes in the central nervous system and inner ear, based on microcirculatory disorders.
On the activities of German medical scientists in the first half of the 19th century at Kazan University
Authors: Albitsky V. Yu. , Gallyamov A. B.
Published: March 2022

In assessing the role of German physicians in the history of Russian medicine for a long time there were two mutually exclusive concepts: one of them extremely exaggerated this role, completely denying the identity of Russian medical thought in the first half of the last century, the other - negatively assessed the foreign experience and activities of foreign physicians in Russia. However, an unambiguous assessment of the activities of German medical scientists is erroneous. This is clearly evidenced by the data on their activities at Kazan University.
Dimeksid-mud applications in the complex spa therapy of cervical osteochondrosis
Authors: Pugachev M. N.
Published: March 2022

Among spa factors for neurological manifestations of degenerative pathology of the cervical spine segmental application of mud at a temperature of 37-42 on the cervical collar zone or on this area and hand is widely used.

Dimexide (DMSO, dimethylsulfoxide) is used in the treatment of many diseases as a non-aqueous solvent of drugs. It has a mild analgesic effect, has a favorable trophic effect, is easily absorbed by the skin and transports along with it other substances.
III All-Union Congress of Endocrinologists
Authors: Bulatova T. V. , Zyangirova S. T.
Published: March 2022

The congress was opened by A. N. Demenkov, Head of the Department of Specialized Medical Care of the USSR Ministry of Health. In his report he pointed out radical changes in the structure of the service: reorganization of anti-obesity dispensaries into endocrinology centers; by 1991 they would open in all capitals of Union republics, regional and territorial centers and become organizational and methodological centers. In addition, in 1990 it is planned to establish endocrinology departments, including children's and surgical ones, in all large multidisciplinary hospitals.
Danube Symposium on the History of Medicine
Authors: Khalikov A. Kh
Published: March 2022

The International Danube Symposium on the History of Medicine, organized by the Union of Scientific Medical Societies of Bulgaria and the Bulgarian Society of Medical History, was held under the auspices of the President of the International Association of Medical Historians, Professor X. Scharewald, Honorary Chairman of the Bulgarian Society of Medical History, Professor V. Pavlova and Corresponding Member of the AMS USSR, Professor B. D. Petrov.
Surgical treatment of pancreatic pseudocysts
Authors: Gagushin V. A.
Published: March 2022

Clinically and morphologically the cyst is an intermediate stage between acute and chronic pancreatitis. In the early stage of the disease, i.e. in absence of capsule, pancreatic juice leakages in retroperitoneal tissue, small omental pouch, inside pancreatic parenchyma cannot be anatomically considered a cyst, but since they are initial substrate for its formation, they are eligible to be called cysts in unstable stage. According to some authors, in the early stages of cysts should be treated conservatively, while others believe that surgical treatment should be carried out immediately after diagnosis, before a dense capsule develops, which takes 2-4 months to form.
Duodenal ulcer and stomach polyps
Authors: Vasiliev Yu. V. , Boldyreva L. I.
Published: March 2022

It is known that diseases of the upper digestive tract may be combined. Therefore, timely diagnostics of basic and concomitant pathology as well as treatment of patients taking into account these diseases have an important practical value. In particular, until now a number of points concerning duodenal ulcer, which can be combined with gastric polyposis, are not clear. How often does duodenal ulcer disease combine with gastric polyps? Should gastric polyps be removed in such patients, given the possibility of their malignant origin, and is gastric polyp outgrowth possible in patients with duodenal ulcer disease? Is it reasonable to remove gastric polyps during the acute period of duodenal ulcer disease using endoscopic gastric polypectomy?
Endolymphatic antibiotic therapy of local purulent process
Authors: Lebedeva T. P. , Begshiyev O. B. , Konychev A. V. , Vlasova L. M.
Published: March 2022

The increase in the number of patients with purulent diseases in the last decade is due to the allergization of the population, the increasing number of patients with diabetes mellitus, the appearance of associations of microbial flora with high virulence and the increasing number of antibiotic-resistant forms. To achieve a clinical effect, it is necessary to increase therapeutic doses of antibiotics, while they themselves are toxic and reduce immunity indicators, increasing the body's susceptibility to infection. With traditional methods of administration, antibiotics are not always able to inhibit the growth and reproduction of microorganisms. It is known that localization and spread of microorganisms occur mainly in the lymphatic system. Therefore, today the most rational and effective is the method of endolymphatic administration of antibiotics, which manages to create a sufficient concentration of antibiotic in the pyo-inflammatory focus and the surrounding tissues within 24 hours after a single therapeutic dose administration.
Clinical and roentgenologic operations for a supraacetabular "shed" formation in dysplastic coxarthrosis
Authors: Akberdina D. L. , Gimmelfarb A. L. , Shirshova L. A.
Published: March 2022

Dysplastic coxarthrosis is one of the most common and rapidly progressing forms of arthritis. Its early stages are treated operatively with complex reconstructive and reconstructive surgeries on the pelvic and femoral bones.
Muscle plasty in surgical treatment of congenital dislocation of the hip in children
Authors: Gafarov Kh. Z. , Akhtyamov I. F.
Published: March 2022

Active development of extra-articular, low-traumatic methods of surgical treatment of congenital dislocation of the femur has reduced the number of such postoperative complications as relaxation, decentration, and aseptic necrosis of the femoral head by now. As a rule, the main focus of research is on surgeries with correction of the pelvic and femoral components. But it is not uncommon that even correctly performed open reduction of congenital dislocation of the femur and restoration of proper coaptation of the articular surfaces end in failure. Lateroposition, decentration, or even reluxation occur either immediately after removal of the plaster immobilization or in the course of active physical and mechanical therapy. One of the main reasons for such failures is the imbalance between the internal and external rotators of the femur that occurs after correction of the anteversion angle.
Application of Laparoscopy for Differential Diagnosis of Acute Genital Diseases in Emergency Surgery
Authors: Kim I. A.
Published: March 2022

Differential diagnosis of acute inflammatory diseases of the genitals and acute surgical pathology (often acute appendicitis) is still an urgent issue in emergency surgery. According to our data, gynecological diseases occurred in 4.8% of patients admitted to the clinic with suspected acute appendicitis. Any suspicion of gynecological disease requires a thorough examination of the patient and a detailed collection of her gynecological anamnesis. Of course, not every gynecological disease is difficult to diagnose. Sometimes the absence of clear signs of acute genital diseases and acute appendicitis leads to diagnostic errors and unwarranted laparotomies. At the same time, waiting tactics in patients with unclear clinical picture is fraught with disease progression and development of complications. Therefore, accurate and timely diagnostics will allow to exclude unnecessary laparotomies and prevent both pathological process progression and its complications.
Treatment of atopic bronchial asthma with medium doses of theophylline
Authors: Tsybulkin A. P. , Rakhmatullina N. M.
Published: March 2022

Drug therapy of bronchial asthma currently remains the most effective and affordable method of treatment. The main medications are sympathomimetics and adrenolin-like substances, intal, steroids and methylxanthines. Methylxanthine derivatives, particularly theophylline, as bronchodilators have been known since 1924. In recent years there has been renewed interest in the clinical pharmacology of the drug. The effectiveness of theophylline is largely due to the use of very high doses of the drug, bordering on toxic. A pronounced therapeutic effect occurs when the concentration of theophylline in the patient's blood reaches 10-12 g/ml. Severe complications in the form of arrhythmia, respiratory arrest, gastric bleeding occur at a concentration of 15-20 g/ml.
Treatment of chronic nongonococcal urethritis with autologous blood instillations
Authors: Suvorov A. P. , Kaplanov V. D. , Denisov S. N. , Leshchinskaya L. B.
Published: March 2022

Inflammation of the urethra in men often continues (and progresses) for a long time after the etiological factor (gonococcus, trichomonads, viral infection, etc.) is eliminated. A prolonged inflammatory reaction is caused by a number of reasons and primarily by the decrease of local protective properties of the mucous membrane as a result of inflammation and destructive processes.
Clinical and radiological features of remote consequences of birth injuries of the spine and spinal cord in children
Authors: Zatekina O. I. , Morozova E. A.
Published: March 2022

Clinical manifestations of birth injuries of the central nervous system are polymorphic and depend on the level of damage to the structures of the nervous system. Clinicians often encounter subclinical manifestations of natal injuries, especially of birth injuries of the spinal cord. Subsequently, it is these undetected natal injuries that cause the so-called delayed neurological disorders. Late neurological complications can occur in the weeks and months of a child's life, as well as many years later. Patients of the neurologist are children with headaches due to chronic and cerebral vascular insufficiency, early cervical osteochondrosis, postural disorders, transient disorders of spinal circulation developed as a result of instability of previously injured vertebrae, with cerebral circulation disorders of the ischemic type from mild dyshemia to severe ischemic strokes with all the typical symptoms.
Dynamics and prognostic value of morphological changes of regional lymph nodes to a cancerous tumor
Authors: Tsyplakov D. E. , Dobrynin V. A.
Published: March 2022

Increasing morbidity and high mortality of patients with cancer of different organs dictate the necessity to search for effective methods of early diagnosis and treatment of malignant neoplasms as well as to study the factors determining the course of the disease and its prognosis. The successful solution of these tasks is impossible without thorough investigation of the functional morphology of the lymph nodes adjacent to the tumor, which play the role of the first barrier in the path of cancer metastasis. Finding out the role of lymph nodes in tumor metastasis is one of the major issues of modern oncology, because presence of metastases in regional lymph nodes worsens prognosis considerably, decreasing 5-year survival period.
Toward a technique of tissue dissection with focused laser radiation
Authors: Kochenov V. I.
Published: March 2022

A number of difficulties in laser tissue dissection are associated with the appearance of liquid ingredients in the wound - blood, lymph, molten fat. The liquid ingredients constantly enter the depth of the incision, cover the tissue to be further dissected, and the laser radiation evaporates them before they interact with the wound bed. This leads to inefficient energy expenditure, formation of coagulation crust, especially with prolonged blood evaporation, which prevents further dissection, worsens wound healing conditions. Constant blood flowing to the bottom of the wound prevents visibility of the incision.
Electroenterography in the assessment of gastrointestinal motor function abnormalities in patients with acute intestinal obstruction
Authors: Krasilnikov D. M. , Karpukhin O. Yu.
Published: March 2022

Intestinal obstruction has been and remains one of the urgent and difficult problems of surgery. There is a steady increase in the number of patients with this pathology, a large number of postoperative complications and high mortality (from 15 to 30.4%) with no clear tendency to decrease.
Treatment of gynecological patients in the surgical department
Authors: Fattakhov V. V. , Shaihullina F. G.
Published: March 2022

In 1983-1987 in the surgical department of the 10th City Hospital 5352 patients were operated on, 99 (1.9%) of them were operated on because of the gynecological pathology. This group was represented by the following diseases: ectopic pregnancy (21 patients), ruptured ovarian cysts (37 patients); salpingitis of various severity accompanied by peritonitis was found in 41 patients. Among the patients of the latter group, pelvic peritonitis was detected in 21 women, and 12 of them had gonorrheal etiology. Disseminated peritonitis was detected in 20 women.
Device for obtaining mesh skin flaps
Authors: Izmailov G. A. , Garaev R. R. , Sadykova L. M.
Published: March 2022

When repairing skin with extensive skin defects, devices are usually used to obtain mesh grafts from skin flaps with different expansion coefficients. They consist of a cutting element, a supporting roller and a plate. As a cutting element they use special interchangeable knives, a roller with a continuous thread or safety razor blades installed in large numbers (from 50 to 250) perpendicularly to the axis of the rotating roller or to the supporting plate. The main disadvantage of these devices is the difficulty of blanking and changing the cutting elements, which is dangerous and requires not only considerable time, but also a certain qualification of medical personnel.
Л. A. Leschinsky. "Deontology in the Practice of the Therapist." M., Medicine, 1989. Circulation 100,000 copies, 208 pp.
Authors: Bogoyavlenskiy V. F.
Published: March 2022

This monograph is devoted to a little-studied section of the activity of the district physician: the ethics of the relationship between the dualistic unity of "doctor and patient". In fact, since the publication of Academician I. A. Kassirsky's famous monograph "On Doctorship, Problems and Reflections" (1970), there have been no such fundamental publications purposefully written for the general practitioner.
Etiology of scoliosis in children
Authors: Latypov A. L. , Ryzvanov A. A. , Satdarov S. G. , Latypova N. A.
Published: March 2022

The morphology of paravertebral muscles biopsied from 5 patients with scoliosis, as well as muscles autopsied from 35 corpses of newborns and children who died from accidental causes and had no signs of scoliosis, was studied. The asymmetry of the structure of paravertebral muscles in newborns and children, caused by congenital dysplasia of muscle tissue, was found. This asymmetry can be considered as an etiological factor in the onset of scoliosis.
Intertrochanteric osteotomy with the formation of a canopy according to Girgolav in dysplastic coxarthrosis
Authors: Gimmelfarb A. L. , Akberdina D. L.
Published: March 2022

The technique of intertrochanteric osteotomy for dysplastic coxarthrosis in combination with the formation of a canopy from the wing of the ilium according to Girgolav is described. General biological and biomechanical aspects of the operation are discussed.
Pulmonary gas exchange in patients with chronic nonspecific lung diseases
Authors: Andreev V. M.
Published: March 2022

The results of the study of the relationship of all indicators of pulmonary gas exchange in 188 patients with chronic nonspecific lung diseases with obstructive process are presented. It is shown that the cause of respiratory insufficiency and arterial hypoxemia in these diseases are violations of ventilation-diffusion-perfusion relations.
On the possibility of local outbreaks of tuberculosis during the endemic period
Authors: Ivanova L. S. , Kozlenko L. S. , Volchkova I. L.
Published: March 2022

Of the group of children who had been in contact with an unknown source of tuberculosis infection for no more than 6 months, 35.1% were infected and 9.4% of children became ill with intra-thoracic tuberculosis. This situation is interpreted as a local outbreak of the disease during the endemic period of tuberculosis caused by an unknown source of infection in children with reduced specific immunity.
The state of some indicators of hemostasis and kallikrein-kinin system in patients with atherosclerotic occlusion of the arteries of the lower extremities
Authors: Rzaev N. M. , Kazieva N. K. , Sultanova T. I.
Published: March 2022

Based on the results of the study of hemostasis and kallikrein-kinin system indicators in patients with atherosclerotic occlusion of the arteries of the lower extremities, an increase in kinpnoobrazovatelny function and increased fibrinolysis were established while maintaining a high thrombotic potential of the blood. In complex therapy for uncomplicated course of the disease, it is necessary to include activators of the kallikrein-kinin system (padutin, delminal, etc.), and in complicated course inhibitors (anginin, prodectin).
Effect of modification of the protein part of thromboplastin (factor III) on its interaction with factors VII and Viii
Authors: Baykeev R. F. , Chenborisova G. S.
Published: March 2022

The effect of enzymatic modification of the protein part of thromboplastin on its interaction with factors VII and V. was studied. It has been shown that the effect of papain on apoprotein disrupts the interaction of these factors with thromboplastin, resulting in the formation of a factor X activator with less activity than before modification.
Immunotherapy of patients with chronic nonspecific salpingoophoritis
Authors: Maltseva L. I. , Molotilov B. A. , Kapeliushnik N. L.
Published: March 2022

The state of cellular and humoral immunity was studied in 80 patients with chronic nonspecific salpingoophoritis. At the stage of remission of the process, a comprehensive allergological examination was carried out. Bacterial sensitization was diagnosed in 41 patients, 19 of them monovalent, mainly to staphylococcus, 22 - in polyvalent combinations. Sensitization determined the nature of changes in the indicators of specific immunity and the features of the clinical course of the disease. Differentiated therapy was carried out taking into account the altered reactivity by the method of specific hyposensitization with bacterial allergens and levamisole. Sustained remission was obtained.
The content of free amino acids in blood serum in chronic myeloid leukemia and idiopathic myelofibrosis
Authors: Klyushkin I. I.
Published: March 2022

Treatment of open limb injuries remains one of the urgent and not yet fully resolved issues in modern traumatology (13, 18, 29, 37). Significant frequency of these injuries [50], a large number of complications [17, 19, 52, 54], unsatisfactory outcomes, a fairly high percentage of disability and mortality make this a major problem in traumatology. Due to the increased industrialization of the country, an increase in the fleet of heavy-duty and high-speed vehicles, intensive construction of high-rise buildings [38], the number of severe open limb injuries has increased. The specific weight in the total number of diaphyseal fractures ranges from 27.3 to 53% [10, 31, 53, 57]. Very often, open injuries of long tubular bones are combined with traumatic brain injury, shock, blood loss, severe damage and crushing of soft tissues and vascular, nerve formations [29, 53]
Clinical forms of vertebral deformity in patients with lumbar osteochondrosis
Authors: Veselovsky V. P. , Ladygin A. P.
Published: March 2022

On the basis of clinical and instrumental examination of 168 patients with lumbar osteochondrosis, three forms of vertebral deformities were identified: functional, functional-organic and organic. These forms represent a sequential chain of biomechanical adaptation of patients. Analysis of the influence of vertebral deformities on the clinical manifestations of the disease showed that the most favorable form is organic, and the least favorable functional-organic. In the organic form, the minimum severity of painful muscle-tonic and neurodystrophic syndromes of the disease, the shortest duration of exacerbation and a longer remission were observed. In the functional-organic form, on the contrary, reflex syndromes were most pronounced.
The role of the neural scar in the pathogenesis of the secondary contracture of the facial muscles
Authors: Ivanichev G. A.
Published: March 2022

The hypothesis was tested that the artificial synapse in the area of ​​the neural scar is the role of the pathogenetic factor in the origin of the secondary contracture of the facial muscles. The distal branches of the facial nerve were alternately stimulated. A possible orthodromic response, capable of moving to adjacent fibers in the zone of the neural scar, was recorded in the frontal muscle (upon stimulation of the lower branch) and chin (upon stimulation of the upper branch). The results of studying the direct M-response and trigeminofacies reflex of these muscles are presented. The possibility of transverse transition of impulses was established only in the acute stage of facial neuritis. The involvement of the neural scar in contracturogenesis has not been confirmed.
Diagnosis of autoaggressive processes in liver diseases
Authors: Starkova N. V.
Published: March 2022

Among the immunological methods of diagnosing liver diseases to detect autoimmune processes, the reaction of inhibition of leukocyte migration using water-salt extracts or liver tissue homogenates is known.
Gunshot wound to the stomach and pancreas
Authors: Romashev P. N. , Mamistov V. A.
Published: March 2022

K., 22 years old, entered the surgical department on 30/V 1975 at 23:25 with complaints of a wound and severe pain in the left hypochondrium. At 22 o'clock he was wounded by a pistol shot.
Diagnostics of the colon diverticulosis
Authors: Avdonin S. I. , Kharitonov R. K. , Fayzullin M. K. , Starostin A. P.
Published: March 2022

The analysis of clinical and radiological manifestations of colon diverticular disease was carried out taking into account new data on the nature and classification of this disease (152 patients). Methodological techniques are proposed to help identify the indicated pathology and carry out differential diagnostics.
Epidemiological characteristics of salmonellosis in the Tatar ASSR
Authors: Mukhutdinov I. Z. , Yakobson D. A. , Khamitova O. M. , Koksina K. D. , Bulaeva P. M. , Gadelshina A. M. , Gerasimova L. V. , Ismagilova Z. М. , Anderzhanova F. G. , Bocharova E. P. , Zemanova V. U. , Danilina G. V.
Published: March 2022

The main regularities of the epidemic process of salmonellosis in the Tatar ASSR for 1960-1980 are characterized. In various administrative territories, the epidemic process of salmonellosis has common patterns. The increase in morbidity since 1976 is mainly due to the nosocomial spread of the disease among young children.
Regional features of malaria epidemiology
Authors: Yahod D. B. , Fomenkova L. I. , Akhmetshin N. A.
Published: March 2022

Imported cases of malaria have been noted in the TASSR over the past 3 years. During the medical care of patients, a number of mistakes were made that could lead to the occurrence of local cases of the disease. In order to preserve epidemiological well-being in the republic, it is necessary to carry out a full range of preventive and anti-epidemic measures.
Idiopathic osteonecrosis of the femoral head in adults
Authors: Prokhorov V. P.
Published: March 2022

Idiopathic osteonecrosis (IO) of the femoral head in adults is a serious disease that leads to permanent disability at the most working age (in the 3-5th decade of life). Its essence lies in subchondral necrosis of the bone matter of the head in the upper, most loaded segment, followed by impaction of the head and the development of the most severe deforming arthrosis. The disease develops spontaneously, for no apparent reason, and should be distinguished from post-traumatic head necrosis after neck fractures and hip dislocations.
Modern radiopaque diagnostics of the consequences of vertebrospinal trauma
Authors: Kamalov I. I.
Published: March 2022

The diagnosis, treatment and outcome of vertebrospinal trauma are determined not only by the primary damage to the vertebrae, surrounding tissues and vessels, but also by the emerging cicatricial and adhesive processes in the membranes of the spinal cord and in the epidural tissues, the development of secondary irreversible degenerative-dystrophic disorders and post-traumatic deformities. This leads to a disorder of the lymph and blood circulation, to ischemia, hypoxia of the spinal cord, and the development of secondary compression syndrome.
Study of the impact of atmospheric pollution on public health
Authors: Dautov F. F.
Published: March 2022

In recent years, the study of the impact of air pollution on the health of the population is of utmost importance. In 1957, temporary guidelines were issued for the study of the influence of atmospheric air pollution on the health and sanitary and hygienic conditions of the population, in 1962 - instructive and methodological guidelines for organizing the study of atmospheric air pollution, in 1976 - temporary instructive and methodological guidelines for assessing the degree of air pollution. However, unified research methods and criteria for the influence of atmospheric air pollution on public health have not yet been developed. Internationally unified methodologies for studying the dependence of public health on the state of the environment are the most important area of ​​scientific research in general and communal hygiene.
Working conditions and morbidity with temporary disability of workers engaged in the production of polymetallic catalysts for the oil refining industry
Authors: Valishin B. S.
Published: March 2022

The working conditions and health status of workers at the 3 largest catalyst factories in the country were studied, where alumino-silicate and aluminum-cobalt-molybdenum catalysts are produced. The main hygienically unfavorable factors in both industries are air pollution of the working areas with catalyst dust, high air temperature and industrial noise in some areas. Among the nosological forms, acute respiratory diseases, tonsillitis, pustular diseases of the skin and subcutaneous tissue occupy the leading places both in the frequency of cases and in days of disability per 100 workers. All indicators of morbidity in most cases were higher among workers at the production of an aluminum-cobalt-molybdenum catalyst. The level of morbidity in the studied industries is influenced by the duration of exposure to adverse factors and the nature of harmful substances.
Actual problems of the antenatal clinic
Authors: Shinkareva L. F. , Chirkova A. V. , Sabsay M. I. , Serebrennikova K. G. , Zhdanova V. I.
Published: March 2022

The decisions of the XXVI Congress of the CPSU and the decree of the Central Committee of the CPSU and the Council of Ministers of the USSR "On additional measures to improve the health of the population" set new tasks for Soviet health care, the most important of which are improving the quality of obstetric and gynecological care, prevention and early detection of diseases, and improving women's health and children and their dispensary observation.
Predicting septic complications after cesarean section in a antenatal clinic
Authors: Gladun E. V. , Etsko L. A. , Etsko K. P.
Published: March 2022

In recent years, a number of authors [1, 3 - 5] to substantiate the differentiated observation and health improvement of various dispensary groups use mathematical methods that make it possible to scientifically predict the course of the disease No. to influence its outcome. In the available literature, we did not find any reports on predicting septic complications in extraperitoneal caesarean section.
The value of a specialized holiday home for reducing perinatal pathology and complications during pregnancy and childbirth
Authors: Gilyazutdinova Z. S. , Zhivulko L. G. , Bievchenko G. T. , Biktimirova N. F.
Published: March 2022

The protection of women's health in the USSR is not only a departmental function of the health authorities, it is ensured by a complex of socio-economic measures that have made it possible to reduce obstetric and perinatal pathology. In the field of maternal and child health care, specific preventive measures are being implemented following the decisions of the XXVI Congress of the CPSU and the decisions of the Central Committee. The CPSU and the Council of Ministers of the USSR 'to further improve the protection of public health.