bluuebunny/crossref_metadata_2025 huggingface dataset:
Intermittent sliding-lock-knot suture for limbal conjunctival autograft fixation in pterygium surgery: a technique note
Authors:   Department of Ophthalmology, the Second Affiliated Hospital, Fujian Medical University, Quanzhou 362000, Fujian Province, China, Zhang Ling , Wang Jing-Ru ,   Department of Ophthalmology, the Second Affiliated Hospital, Fujian Medical University, Quanzhou 362000, Fujian Province, China, Shi Wen-Jian ,   Department of Ophthalmology, the Second Affiliated Hospital, Fujian Medical University, Quanzhou 362000, Fujian Province, China, Zheng Feng ,   Department of Neurosurgery, the Second Affiliated Hospital, Fujian Medical University, Quanzhou 362000, Fujian Province, China, Gao Ying-Ying ,   Department of Ophthalmology, the Second Affiliated Hospital, Fujian Medical University, Quanzhou 362000, Fujian Province, China
Published: April 2024

AIM: To report a technique used with intermittent sliding-lock-knot (ISLK) fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent (RI) fixation.
METHODS: Consecutive patients with primary pterygium who had undergone pterygium excision combined with limbal conjunctival autograft transplantation between March 2021 and March 2022 at our institute were retrospectively analyzed. Primary outcome measures were mean duration of surgery and suture removal, degree of conjunctival hyperemia on postoperative day 1, pain score at suture removal, postoperative symptoms at 6mo, including conjunctival hyperemia, foreign body sensation, and graft stability.
RESULTS: Ninety-eight patients underwent monocular surgery and were divided into ISLK (51 eyes) and RI (47 eyes) groups according to the type of conjunctiva autograft fixation method planned. There was no significant difference in mean duration of surgery between the two groups (18.59±2.39min vs 18.15±2.20min, P=0.417); however, compared to the RI group, shorter suture removal times were observed in the ISLK group [0.58min (0.42-0.87) vs 3.00min (2.21-4.15), P<0.001]. The degree of conjunctival hyperemia on postoperative day 1 was milder in the ISLK group (P<0.001). Pain scores at suture removal were lower in the ISLK group than in RI group [1 (0-3) vs 2 (1-4), P<0.001]. Postoperative symptoms at 6mo were comparable between the groups (P=0.487), with no recurrence.
CONCLUSION: ISLK is an innovative method for limbal conjunctival autograft fixation after pterygium excision. Compared to RI fixation, ISLK facilitates suture removal and reduces discomfort, with comparable surgery duration and less conjunctival hyperemia.
MP-3 microperimeter in early primary open angle glaucoma with a new pattern
Authors:   Department of Ophthalmology of the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China, Liang Shuang , Liu Xiao-Li ,   Department of Ophthalmology of the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China, Duan Jia-Liang ,   Department of Ophthalmology of the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China, Liu Dan-Yan ,   Department of Ophthalmology of the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Published: April 2024

AIM: To investigate macular microperimetry in patients with early primary open angle glaucoma (POAG) using a new custom-made pattern, and analyze the characteristics of macular sensitivity.
METHODS: This case-control study included 38 patients with POAG, who were divided into pre-perimetric glaucoma (18 eyes of 18 patients), early-stage (20 eyes of 20 patients), and control (20 eyes of 20 patients) groups. All subjects underwent standard 24-2 humphrey visual field test. An MP-3 microperimeter with a new custom-made pattern (28 testing points distributed in four quadrants, covering the central 10° of the retina) was used to evaluate macular sensitivity. Ganglion cell complex (GCC) thicknesses were examined using an RS-3000 Advance OCT system. The features of structure and function were analysed per quadrant.
RESULTS: The pre-perimetric glaucoma group had significantly lower inferior hemifield macular sensitivity compared to controls (P<0.05). The early-stage POAG group had significantly lower average, inferior hemifield, inferonasal, and inferotemporal mean sensitivities compared to the pre-perimetric glaucoma group (P<0.05), and lower macular sensitivity in all sectors compared to controls (P<0.05). Regarding GCC thickness, all sectors in the early-stage POAG group became thinner compared to those in controls (P<0.05); whereas all sectors in the early-stage POAG group, except the superonasal quadrant, became thinner compared to those in the pre-perimetric glaucoma group (P<0.05). Macular sensitivity and GCC thickness were significantly associated in each sector. The inferotemporal quadrant had the highest correlation coefficients (0.840). The structure-function relationship for the inferonasal and inferotemporal sectors was stronger compared to the corresponding superior sectors.
CONCLUSION: Microperimetry reveals variations in macular sensitivity in patients with early glaucoma earlier than conventional perimetry, particularly in pre-perimetric glaucoma cases in which it might be undetectable by conventional methods. The new custom-made pattern may improve the accuracy of microperimetry by enhancing point arrangement and reducing fatigue effects. Macular sensitivity measured by MP-3 with this pattern shows statistically significant structural and functional associations with the thicknesses of the GCC.
Risk factors of non-arteritic anterior ischaemic optic neuropathy and central retinal artery occlusion
Authors:   Department of Ophthalmology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China, Ma Chu-Han , Dai Ting-Ting ,   Department of Ophthalmology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China, Chen Ting-Ting ,   Department of Ophthalmology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China, Zhu Wen-Hui ,   Department of Ophthalmology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
Published: April 2024

AIM: To investigate the difference in risk factors between non-arteritic anterior ischaemic optic neuropathy (NAION) and central retinal artery occlusion (CRAO) and develop a predictive diagnostic nomogram.
METHODS: The study included 37 patients with monocular NAION, 20 with monocular CRAO, and 24 with hypertension. Gender, age, and systemic diseases were recorded. Blood routine, lipids, hemorheology, carotid and brachial artery doppler ultrasound, and echocardiography were collected. The optic disc area, cup area, and cup-to-disc ratio (C/D) of the unaffected eye in the NAION and CRAO group and the right eye in the hypertension group were measured.
RESULTS: The carotid artery intimal medial thickness (C-IMT) of the affected side of the CRAO group was thicker (P=0.039) and its flow-mediated dilation (FMD) was lower (P=0.049) than the NAION group. Compared with hypertension patients, NAION patients had higher whole blood reduced viscosity low-shear (WBRV-L) and erythrocyte aggregation index (EAI; P=0.045, 0.037), and CRAO patients had higher index of rigidity of erythrocyte (IR) and erythrocyte deformation index (EDI; P=0.004, 0.001). The optic cup and the C/D of the NAION group were smaller than the other two groups (P<0.0001). The diagnostic prediction model showed high diagnostic specificity (83.7%) and sensitivity (85.6%), which was highly related to hypertension, the C-IMT of the affected side, FMD, platelet (PLT), EAI, and C/D.
CONCLUSION: CRAO patients show thicker C-IMT and worse endothelial function than NAION. NAION and CRAO may be related to abnormal hemorheology. A small cup and small C/D may be involved in NAION. The diagnostic nomogram can be used to preliminarily identify NAION and CRAO.
Diagnostic values of questionnaires of Convergence Insufficiency Symptom Survey and College of Optometrists Vision Development Quality of Life in the screening of convergence insufficiency
Authors:   Department of Ophthalmology, West China Hospital, Sichuan University/Laboratory of Optometry and Vision Science, West China School of Medicine, Chengdu 610041, Sichuan Province, China, Xiong Ling , Wu Ye ,   Department of Ophthalmology, West China Hospital, Sichuan University/Laboratory of Optometry and Vision Science, West China School of Medicine, Chengdu 610041, Sichuan Province, China
Published: April 2024

AIM: To compare and analyse the diagnostic efficacy of the College of Optometrists Vision Development Quality of Life Questionnaire (COVD-QOL) and the Convergence Insufficiency Symptom Survey (CISS) in detecting convergence insufficiency and to compare their diagnostic value in clinical applications.
METHODS: Using the diagnostic test method, 62 adult patients with convergence insufficiency (age: 24.74±3.75y) and 62 normal participants (age: 23.61±3.13y) who visited the Optometry Clinic of West China Hospital of Sichuan University from April 2021 to January 2023 were included. All subjects completed the CISS and COVD-QOL. Statistical analysis of the sensitivity and specificity of the CISS and COVD-QOL and comparison and joint experimental analysis of their diagnostic efficacy were performed.
RESULTS: The sensitivity of the CISS and COVD-QOL for convergence insufficiency was 64.5% and 71.0%, respectively, while the specificity was 96.8% and 67.7%, respectively. Compared to the CISS alone, the combination of the CISS and COVD-QOL demonstrated lower sensitivity and specificity. The areas under the receiver operating characteristic curve of CISS, COVD-QOL and CISS combined with COVD-QOL were 0.806, 0.694 and 0.782, respectively.
CONCLUSION: Considering the low sensitivity of the CISS and the low specificity of the COVD-QOL, it is recommended to supplement these questionnaires with other screening tests for the detection of convergence insufficiency.
Prognostic factors and clinical features of rhino-orbital-mucormycosis cases: an update for patient and visual survivals
Authors:   Department of Ophthalmology, Cukurova University Faculty of Medicine, Saricam, Adana 01330, Türkiye, Aksoy Mustafa , Ulas Burak ,   Department of Ophthalmology, Cukurova University Faculty of Medicine, Saricam, Adana 01330, Türkiye
Published: April 2024

AIM: To determine the frequency of patients’ vision survival and prognostic factors and evaluate clinical features in rhino-orbital mucormycosis.
METHODS: Forty-three eyes of 43 patients followed up with orbital mucormycosis infections were included in the study. Demographic characteristics of the patients, symptoms at admission, ophthalmologic and non-ophthalmologic examination findings, clinical findings during follow-up, medical and surgical procedures, and complications were recorded. Patient survival was determined by assessing the incidence of mortality, and vision survival was defined as achieving a final visual acuity of at least light perception.
RESULTS: Twenty-seven (62.8%) patients were male, and 16 (37.2%) were female. When the underlying disease status of the patients was examined, it was observed that all patients had an underlying disease and diabetes constituted the majority (65.2%). Periorbital swelling (69.8%) and ophthalmoplegia (53.5%) were the most common symptoms and findings at the admission of patients with mucormycosis infection. The disease resulted in death in 22 (51.2%) patients. The presence of fever and shorter duration of antifungal therapy were associated with lower patient survival. Exenteration surgery was not found to be associated with the survival of the patients. Frozen eye, loss of pupillary light reflex, and development of central retinal artery occlusion were associated with lower vision survival.
CONCLUSION: This study presents one of the most extensive patient series in the literature on rhino-orbital mucormycosis. Knowing the patients’ symptoms at the time of admission and the clinical findings during the infection process will increase awareness about the disease.
Prevalence of visual impairment and estimation of refractive errors among school children in Kakamega, Kenya
Authors:   Department of Optics and Optometry and Vision Sciences, Universidat de València, Burjassot, Valencia 46010, Spain; NGO Vision Without Borders (Visio Sense Fronteres, VSF), Calpe 03710, Alicante, Spain; Masinde Muliro University of Science and Technology, P.O Box 190 - 50100, Kakamega, Kenya, Signes-Soler Isabel , Nangena Sheilah ,   Masinde Muliro University of Science and Technology, P.O Box 190 - 50100, Kakamega, Kenya, Wekesa Andrew ,   Masinde Muliro University of Science and Technology, P.O Box 190 - 50100, Kakamega, Kenya, Llamusí Raúl Montalbán ,   NGO Vision Without Borders (Visio Sense Fronteres, VSF), Calpe 03710, Alicante, Spain; Clinica Baviera Alicante C/Ausó y Monzó, 16, Alicante 03006, Spain
Published: April 2024

AIM: To investigate the prevalence of visual impairment (VI) and provide an estimation of uncorrected refractive errors in school-aged children, conducted by optometry students as a community service.
METHODS: The study was cross-sectional. Totally 3343 participants were included in the study. The initial examination involved assessing the uncorrected distance visual acuity (UDVA) and visual acuity (VA) while using a +2.00 D lens. The inclusion criteria for a subsequent comprehensive cycloplegic eye examination, performed by an optometrist, were as follows: a UDVA<0.6 decimal (0.20 logMAR) and/or a VA with +2.00 D ≥0.8 decimal (0.96 logMAR).
RESULTS: The sample had a mean age of 10.92±2.13y (range 4 to 17y), and 51.3% of the children were female (n=1715). The majority of the children (89.7%) fell within the age range of 8 to 14y. Among the ethnic groups, the highest representation was from the Luhya group (60.6%) followed by Luo (20.4%). Mean logMAR UDVA choosing the best eye for each student was 0.29±0.17 (range 1.70 to 0.22). Out of the total, 246 participants (7.4%) had a full eye examination. The estimated prevalence of myopia (defined as spherical equivalent ≤-0.5 D) was found to be 1.45% of the total sample. While around 0.18% of the total sample had hyperopia value exceeding +1.75 D. Refractive astigmatism (cil<-0.75 D) was found in 0.21% (7/3343) of the children. The VI prevalence was 1.26% of the total sample. Among our cases of VI, 76.2% could be attributed to uncorrected refractive error. Amblyopia was detected in 0.66% (22/3343) of the screened children. There was no statistically significant correlation observed between age or gender and refractive values.
CONCLUSION: The primary cause of VI is determined to be uncorrected refractive errors, with myopia being the most prevalent refractive error observed. These findings underscore the significance of early identification and correction of refractive errors in school-aged children as a means to alleviate the impact of VI.
Bibliometric analysis of hotspots and trends of global myopia research
Authors:   Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China, Wu Xing-Yang , Xu Yan-Wu ,   School of Future Technology, South China University of Technology, Guangzhou 510641, Guangdong Province, China, Zhang Yan-Ling ,   Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China, Zhang Shao-Chong ,   Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China, Yang Wei-Hua ,   Shenzhen Eye Institute, Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, Guangdong Province, China
Published: April 2024

AIM: To gain insights into the global research hotspots and trends of myopia.
METHODS: Articles were downloaded from January 1, 2013 to December 31, 2022 from the Science Core Database website and were mainly statistically analyzed by bibliometrics software.
RESULTS: A total of 444 institutions in 87 countries published 4124 articles. Between 2013 and 2022, China had the highest number of publications (n=1865) and the highest H-index (61). Sun Yat-sen University had the highest number of publications (n=229) and the highest H-index (33). Ophthalmology is the main category in related journals. Citations from 2020 to 2022 highlight keywords of options and reference, child health (pediatrics), myopic traction mechanism, public health, and machine learning, which represent research frontiers.
CONCLUSION: Myopia has become a hot research field. China and Chinese institutions have the strongest academic influence in the field from 2013 to 2022. The main driver of myopic research is still medical or ophthalmologists. This study highlights the importance of public health in addressing the global rise in myopia, especially its impact on children’s health. At present, a unified theoretical system is still needed. Accurate surgical and therapeutic solutions must be proposed for people with different characteristics to manage and intervene refractive errors. In addition, the benefits of artificial intelligence (AI) models are also reflected in disease monitoring and prediction.
Corneal collagen cross-linking in patients with keratoconus from the Dresden protocol to customized solutions: theoretical basis
Authors:   Corneal Transplant Center, Pellegrini Hospital, Via Portamedina alla Pignasecca 41, Napoli 80127, Italy, Caruso Ciro , Troisi Mario ,   Eye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples 80131, Italy, Rinaldi Michele ,   Eye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples 80131, Italy, Piscopo Raffaele ,   Eye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples 80131, Italy, Troisi Salvatore ,   Salerno Hospital University, Ophthalmologic Unit, Baronissi, Campania 84131, Italy, Costagliola Ciro ,   Eye Clinic, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples 80131, Italy
Published: April 2024

Keratoconus is an ectatic condition characterized by gradual corneal thinning, corneal protrusion, progressive irregular astigmatism, corneal fibrosis, and visual impairment. The therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages, gas-permeable rigid contact lenses, scleral lenses, implantation of intrastromal corneal ring or corneal transplants for most advanced stages. In keratoconus cases showing disease progression corneal collagen crosslinking (CXL) has been proven to be an effective, minimally invasive and safe procedure. CXL consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation, resulting in stromal crosslinks formation. The aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models, from the original Dresden protocol to the most recent developments in the technique, reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment protocols. Finally, the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted.
Some auxiliary estimates for solutions to non-uniformly degenerate second-order elliptic equations
Authors: Huseynov S. T. , Aliyev M. J.
Published: April 2024

We consider a class of second order elliptic equations in divergence form with non-uniform exponential degeneracy. The method used is based on the fact that the degeneracy rates of the eigenvalues of the matrix ||aij(x)|| (function λi(x)) are not the functions of unusual norm |x|, but of some anisotropic distance |x| a−. We assume that the Dirichlet problem for such equations is solvable in the classical sense for every continuous boundary function in any normal domain Ω.
Estimates for the weak solutions of Dirichlet problem near the boundary point are obtained, and Green’s functions for second order non-uniformly degenerate elliptic equations are constructed.
Beyaz Yakalılarda Duygusal Zekâ ve Narsisizm İlişkisi
Authors: Özkan Sevim , Çoban Kumbalı Hatice , İrmiş Ayşe
Published: April 2024

Bu çalışma duygusal zekâ ile narsisizm arasındaki ilişkiyi araştırmayı amaçlamaktadır. Bu amaçla, Denizli imalat sektöründeki 309 beyaz yakalı çalışana kolayda örnekleme tekniği kullanılarak anket uygulanmıştır. Sonuçlar, duygusal zekâ ile narsisizm arasında pozitif yönlü bir ilişki olduğunu ortaya koymaktadır. Araştırmanın ikinci amacı duygusal zekâ ve narsisizm kavramları ile demografik değişkenler arasındaki ilişkiyi incelemektir. Duygusal zekâ ile cinsiyet ve eğitim durumu arasında anlamlı ilişkiler bulunurken, yaş değişkeniyle anlamlı bir ilişki tespit edilmemiştir. Buna karşılık, narsisizm ve yaş ile narsisizm ve cinsiyet değişkenleri arasında anlamlı bir ilişki bulunurken, eğitim durumuyla anlamlı ilişki olmadığı anlaşılmaktadır. Araştırmanın son amacı, çalışanların duygusal zekâ ve narsisizm özelliklerini yöneticilik statülerine göre incelemektir. Yöneticilerin, yönetici olmayanlara göre duyguları kullanma konusunda daha yetenekli oldukları görülmüştür. Ayrıca narsisizm açısından bakıldığında yöneticiler, yönetici olmayan meslektaşlarına göre daha fazla otoriter özellikler sergileme eğilimindedir.
Risk of Sarcopenia Identified by Sarc-Calf, Nutritional Status and Hand Grip Strength in Patients with Hematological Cancer
Authors: Avancini Lorraine Pires , Costa Laís Freitas da , Vieira Mariana de Souza , Souza Vanusa Felício de , Marques Rayne de Almeida , Marques Rocha Jose Luiz , Petarli Glenda Blaser , Guandalini Valdete Regina
Published: April 2024

Background: Hematological cancer patients are prone to the development of sarcopenia and impaired nutritional and functional status. SARC-CalF is a screening tool for the risk of sarcopenia that has shown good results in this population. This study aimed to identify the risk of sarcopenia by SARC-CalF and to verify its association with nutritional status and Hand Grip Strength (HGS) in patients with hematological cancer.
Materials and Methods: Adult patients, of both sexes, with hematological cancer, and in outpatient care participated in the study. We measured the Hand Grip Strength of the Dominant Hand (HGSD) and the Adductor Pollicis Muscle Thickness of the Dominant Hand (APMTD). Moreover, we applied the Patient-Generated Subjective Global Assessment (PG-SGA) and SARC-CalF. Data were analyzed with SPSS® software, 22.0, with a significance level of 5.0%.
Results: Fifty-one patients aged an average of 60.4 ± 15.1 years were evaluated. Of those, 58.8% were elderly, 51% female, and 80.4% declared themselves non-white. The predominant diagnosis was Mature B Lymphoid Cell Neoplasia (37.7%), and 60.8% of the patients had a diagnosis time of ≤ 3 years. PG-SGA revealed that 35.3% of the patients were malnourished; APMTD and HGSD revealed that 60.8% and 25.5% had reduced muscle strength, respectively. SARC-CalF exposed that 39.2% of the patients were at risk for sarcopenia. Significant associations were found between SARC-CalF and diagnosis time ≤ 3 years (p = 0.039), PG-SGA (p = 0.020), APMTD (p = 0.039) and HGSD (p = 0.002). After binary logistic regression adjusted for age and sex, the reduced HGSD remained associated with the risk of sarcopenia.
Conclusion: SARC-CalF identified a risk of sarcopenia in 39.2% of patients. The reduced HGSD was associated with the risk of sarcopenia.
Gut Microbiota Composition Correlates with Disease Severity in Myelodysplastic Syndrome
Authors: Correia Riello Giovanna Barbosa , Mendonça da Silva Priscila , Da Silva Oliveira Francisca Andrea , Germano de Oliveira Roberta Taiane , Rodrigues da Silva Francisco Eliclecio , Frota França Ivo Gabriel da , Miyajima Fábio , Maciel Melo Vânia Maria , Pinheiro Ronald Feitosa , Macedo Danielle S.
Published: April 2024

The myelodysplastic syndrome (MDS) is a heterogeneous group of clonal disorders of hematopoietic progenitor cells related to ineffective hematopoiesis and an increased risk of transformation to acute myelogenous leukemia. MDS is divided into categories, namely lineage dysplasia (MDS-SLD), MDS with ring sideroblasts (MDS-RS), MDS with multilineage dysplasia (MDS-MLD), MDS with excess blasts (MDS-EB). The International Prognostic Classification System (IPSS) ranks the patients as very low, low, intermediate, high, and very high based on disease evolution and survival rates. Evidence points to toll-like receptor (TLR) abnormal signaling as an underlying mechanism of this disease, providing a link between MDS and immune dysfunction. Microbial signals, such as lipopolysaccharides from gram-negative bacteria, can activate or suppress TLRs. Therefore, we hypothesized that MDS patients present gut microbiota alterations associated with disease subtypes and prognosis. To test this hypothesis, we sequenced the 16S rRNA gene from fecal samples of 30 MDS patients and 16 healthy elderly controls. We observed a negative correlation between Prevotella spp. and Akkermansia spp. in MDS patients compared with the control group. High-risk patients presented a significant increase in the genus Prevotella spp. compared to the other risk categories. There was a significant reduction in the abundance of the genus Akkermansia spp. in high-risk patients compared with low- and intermediate-risk. There was a significant decrease in the genus Ruminococcus spp. in MDS-EB patients compared with controls. Our findings show a new association between gut dysbiosis and higher-risk MDS, with a predominance of gram-negative bacteria.
Potential Ability of Umbilical Cord-Derived Mesenchymal Stem Cells in The Treatment of Premature Ovarian Failure
Authors: Khosravi Samira Mozaffari , Seyedabadin Saman , Shahcheraghi Seyed Hossein , Lotfi Marzieh
Published: April 2024

Introduction: Women of reproductive age may encounter challenges related to infertility or miscarriage, due to conditions such as premature ovarian failure (POF). POF, affecting approximately one percent of women under the age of 40, can lead to infertility. Current data have suggested that utilizing stem cell therapy was the most effective approach for treating POF compared to alternative options. Among the various stem cell types, mesenchymal stem cells derived from the umbilical cord (HUC-MSCs) was a promising choice for treatment due to its features such as relatively low immunogenicity, multipotent, multiple origins, cost-effectiveness, ease of production, and high efficiency.
Conclusion: One of the ways to treat POF is the use of mesenchymal stem cells derived from the umbilical cord, these cells have an extraordinary capacity for repair and regeneration, which helps them in repairing depleted ovaries. The results of this review article indicate that the use of HUC-MSCs can be considered as a potential treatment method in these patients.
Effect of Eight Weeks of Intense Interval Training and Self-Obesity on Serum Lipid Peroxidation Status and Adiponectin Gene Expression in Obese Male Wistar Rats
Authors: Mojarad Amir Falahnezhad , Amini Nastaran , SeyyedAshour SeyyedMostafa
Published: April 2024

Introduction: A high-fat diet and increased calorie intake increase the prevalence of obesity،,which itself causes many diseases. The studies carried out in the field of investigating the mechanisms related to obesity and its related diseases have introduced the increase of fat mass and as a result the disruption of cytokines as one of the most important influencing factors. Therefore, the aim of the current research was the effect of eight weeks of intense interval training on serum lipid peroxidation indices and adiponectin gene expression in obese mice.
Methods: The current research was experimental with a control group. 24 male rats were randomly divided into three control groups, self-obesity group and self-obesity group with high intensity interval training (HIIT). The normal distribution of the data was evaluated using the Shapiro-Wilk test. Then، in order to compare data between groups، one-way analysis of variance was used, and if it became significant، the data were compared using Tukey's post hoc test at a significance level of P < 0.05.
Results: The findings of this research showed that in the exercise group, there was a significant increase in the state of superoxide dismutase (SOD) compared to the self-obesity group. However,, there was no significant change in the level of malondialdehyde (MDA) and the level of adiponectin gene expression in the liver of self-obesity group and interval training group.
Conclusion: Obesity causes an imbalance in the oxidative status and a disturbance in the production and secretion of adiponectin in the liver tissue of obese mice، and intense intermittent exercise improves the oxidative status, but it does not have a significant effect on the expression of the adiponectin gene.
Evaluation of Knowledge and Attitude of Yazd Dental Students in Connection with the Training of Posterior Teeth Restoration with Composite in 2023
Authors: Kalantar Kimia , Davari Abdolrahim , Khoshdel Maede , Ahadi Bita , Shafiei Fahime
Published: April 2024

Introduction: Today, composite resins are a suitable choice for tooth restoration, which in relation to posterior teeth, the most important limitations are marginal leakage, secondary decay, poor load bearing capacity, high wear and inability to restore contact. The durability of posterior restorations especially class II restorations is less compared to amalgam restorations. This has been affected by various factors such as polymerization shrinkage, thermal expansion coefficient and abrasion resistance that limits the durability of the posterior composite.
Methods: The present study was a cross-sectional descriptive study, which 68 final year dental students of School of Dentistry of Shahid Sadoughi University of Medical Sciences in Yazd City were selected by census and their attitude and awareness were studied using a valid and reliable questionnaire containing demographic characteristics and attitude as well as awareness questions. All the data were analyzed in SPSS 16 statistical software. Likert scale was used to measure awareness and attitude.
Results: In the present study, among the 68 final year dental students, 37 students (54.4%) were male 31 students (45/6%) were female the mean and standard deviation of the age of the participants was 25.12 ± 2.3 years. In this study, the mean and standard deviation of total attitude score of final year dental students was equal to 22.80 ± 6.74 and the total attitude score of final year dental students based on Likert Scale was lower than the average. Most of the students reported the quality of posterior composite training to meet practical needs as poor.
Conclusion: Based on the results, the awareness and attitude of final year dental students in relation to posterior composite restoration training was less than average and weak, respectively. There was no significant difference was observed between the knowledge and attitude scores with the gender and age.
Effect of Eight Weeks of Endurance Training on Some Oxidant and Antioxidant Indicators of Testicular Tissue of Diabetic Rats with Acute Morphine Withdrawal Syndrome
Authors: Azarrang Shahram , Parstesh Mohammad , Saremi Abbas
Published: April 2024

Introduction: Diabetes along with morphine causes many metabolic damages in the testicles by causing oxidative stress. This study aimed to reduce the oxidative effects caused by diabetes and morphine on the fertility quality of men with the help of increasing moderate intensity aerobic exercise.
Methods: 32 male Wistar rats were used in this experimental study. Mice were randomly divided into 4 groups of 8: diabetes control (D), morphine diabetes (D. M), diabetes + endurance training (D+ ET), diabetes + morphine endurance training (D. M+ ET). Then induction of diabetes and morphine was done. The training groups performed 8 weeks of endurance training protocol. At the end of the study, all mice were killed and their testis tissue was isolated. The oxidant and antioxidant indices of this study were measured. Data were analyzed by SPSS software version 16 using one-way ANOVA at a significant level of 0.05.
Results: The results showed that the concentration of MDA in the diabetes group had a significant increase compared to other groups (P=0.001). However, increasing endurance training caused a significant decrease in the concentration of MDA (P=0. 001) and a significant increase in the amount of TAC, GPX and SOD (P=0. 001) in other groups compared to the diabetes group.
Conclusion: The present research showed that increasing endurance training with moderate intensity caused a decrease in the oxidant index and an increase in the antioxidant index in the testicular tissue of diabetic rats with withdrawal syndrome. And this shows the reduction of infertility complications in mice.
TIRA — BILGOROD — ASPROKASTRО...: ETHNIC HISTORY OF THE REGION, REFLECTED IN VARIANT CITY NAMES
Authors: Verbych Sviatoslav
Published: April 2024

Introduction. The article offers a historical-linguistic analysis of all known historical variants of the modern oikonym Belgorod-Dniestrovskyi of the Odesa region: Tira, Belgorod, Aspron, Akja Kermen, Asprokastro, Chetatya Albe, Moncastro, Mavrokastro, Albi Kastri, Akkerman. The connection of each name with the corresponding period of the ethnic history of this region is traced — ancient Greek, East Slavic (ancient Ukrainian), Turkic (Tatar), modern Greek, Moldavian (East Romansh), Venetian-Genoese, Turkish, Russian.
Purpose. The author carried out a structural-semantic and etymological analysis of the creative bases of the historical variants of the modern oikonym Belgorod-Dniestrovskyi of Odesa region: Tira, Belgorod, Aspron, Akdja Kermen, Asprokastro, Chetatya Albe, Moncastro, Maokastro, Mavrokastro, Albi Kastri, Akkerman and also traced the connection of the internal form of the specified names with the corresponding stages of the ethnic history of the studied region.
Object of study. Historical variants of the modern oikonym Bilhorod-Dnistrovskyi: Tyra (Tyra), Bѣlъgorodъ, Aspron (’Άσπρoν), Akja Kermen, Asprokastro, Chetatya Albe, Moncastro (Monchastro), Maocastro (Maocastro), Mavrocastro (Maurocastri), Albi Castri (Albi Castri), Akkerman (Акъ-Керменъ, Akierman).
Research methods. Methods of analysis of historical variants of the oikonym Bilhorod-Dnistrovskyi: the descriptive method: the word-forming structure of the given variants is described; the comparative-historical method, by means of which the creative bases of the specified names within the related Indo-European languages are characterized; the comparative method: a systematic comparison of genetically Indo-European names (Greek, Latin, Eastern Romansh, Slavic) with their genetically Turkic (Tatar and Turkish) counterparts; the method of etymological analysis: the etymons of the corresponding oikonymous variants are determined.
Research results. The connection between the oldest name of Bilhorod-Dnistrovskyi — Tira and the corresponding archaic name Dniester has been established. The author assumes its evolution from the Pre-Iranian (Indo-Aryan) form tīvrā, and substantiates (with the involvement of a wide range of related names) the ProtoSlavic archaic of the ancient Ukrainian name Bilhorod ’ Бѣлъгородъ. Therefore, most of the other variants were formed as corresponding semantic loans (Tatar, Modern Greek, Moldavian (Eastern Romansh), Turkish) of the ancient Slavic name Бѣлъгородъ.
Conclusions. The historical-linguistic analysis of the historical variant names of the modern oikonym Bilhorod-Dnistrovskyi — Tira, Бѣлъгородъ, Aspron, Akja Kermen, Asprokastro, Chetatya Albe, Moncastro, Maokastro, Mavrokastro, Albi Castri, Akkerman — proves the connection between the linguistic history of the analyzed variant names and the corresponding ethnic history of the studied region.
ENGLISH SPORTS TERMS IN THE FIELD OF BODYBUILDING AND FITNESS WITH AN ETHNONYMIC ELEMENT
Authors: Ivanova Albena , Kelbecheva Veronika , Yosifova Elena
Published: April 2024

Introduction. The official number of sports disciplines is permanently increasing, and that very fact causes the need to codify new lexical items as well as the existing ones to be periodically verified and edited.
The purpose of the present paper is to represent a list of sports terms in the field of bodybuilding and fitness with an ethnonymic element as well as to give some additional information about their etymology, to prepare an analysis of their structure, to give examples of peculiarities in their usage, if any.
Background and motivations. Such terms with an ethnonym as a part of their structure may be observed in various kinds of sports, but the logical connection between the action and the name of a particular nation is usually and surprisingly not obvious at all, especially for the ordinary people for whom such lexical items are not a part of their everyday vocabulary.
Methodology. The main methods used in the article are the data excerption comparative and structural analyses of the researched examples.
The expected results foresee the description and etymology of the analyzed English sports terms spread today in different classic or modern sports disciplines.
Understanding the Critical Role of Parental Involvement Among Learners in Primary Grades During the New Normal: Challenges and Opportunities
Authors: G. Padillo *Gengen , L. Barillano Michael , C. Berame Flora , P. Manguilimotan Ramil
Published: April 2024

This research delved into the parents’ challenges and opportunities of primary-grade learners enrolled at private and public schools in Cebu, during the school year 2022-2023. The findings formed the basis for the implications for practice. The research used the qualitative-phenomenological method, with 15 parents in private schools in Cebu City Division and 15 parents in public schools in Cebu Province Division as identified participants in the study. It utilized an interpretative phenomenological analysis with the help of an interview guide questionnaire to determine the lived experiences of the parents during the new normal of education. The results of the study revealed that most parents are trying their best to adapt to the new normal set-up of learning—distance education—and most parents described having problems balancing the obligations of work and teaching their learners, as well as with discipline, enthusiasm, availability, accessibility, and learning outcomes. Findings suggest important implications for practice for parents, learners, teachers, school principals, guidance counselors, administrators, researchers, and future researchers. The study concluded that parents have encountered difficulties and prospects while teaching and supervising their primary-grade learners in distance learning during the new normal. It is recommended that the output be implemented.
Fenómenos fonéticos em fronteira de palavra nos dialetos portugueses
Authors: Da Cruz Maria Luísa Segura
Published: April 2024

O artigo apresenta dois fenómenos: (1) inserção de semivogais entre vogais para evitar hiato; (2) alteração de timbre de uma ou das duas vogais em contacto. Caracterizam-se os respetivos contextos de ocorrência e extensão geográfica, ilustrada, quando pertinente, com mapas. Em (1) acrescenta-se à inserção da semivogal palatal, já conhecida, casos, praticamente desconhecidos, de inserção da semivogal velar. A inserção de uma ou de outra está condicionada, pelo ponto de articulação e sobretudo pelo acento. Quando a vogal da direita é acentuada ocorre a semivogal palatal. Quando a vogal da direita é átona é a semivogal velar que aparece. Em (2) apresentam-se casos em que a vogal da direita passa de fechada a aberta e outros em que ambas as vogais se alteram, chegando a inverter-se os graus de abertura das vogais em presença. Procura-se uma interpretação para estes fenómenos.
SOME ISSUES OF THE APPLICATION OF ART. 1192 OF THE CIVIL CODE OF THE RUSSIAN FEDERATION
Authors:   Partner at LGS Legal Services, PhD (Law), Stepanenko Elena K.
Published: April 2024

In this article the author analyses the practical aspects of application of the mandatory rules of direct application (the so-called super-imperative rules) of Russian law, including the qualification of legislative requirements as super-imperative rules, inclusion into such rules of public laws (administrative, currency, etc.), consequences of adoption/enactment of such super-imperative rules for existing contractual relations and, in particular, whether it is possible to use the frustration (impossibility of performance) doctrine. It also analyses the grounds for refusal by Russian courts to apply foreign imperative rules, including such grounds for the refusal as contradiction to Russian public policy (in particular, in case of sanctions introduced by foreign states). The article focuses on application of Article 1192 of the Russian Civil Code, mainly, in the context of foreign sanctions restrictions.
SAFE USE OF HIGHLY-AUTOMATED (UNMANNED) VEHICLES: LEGAL GUARANTEES
Authors:   Head of the Department of Civil Law of the Kutafin Moscow State Law University (MSAL), Judge Emeritus of the Supreme Commercial Court of the Russian Federation, Member of the Council for Codification and Improvement of Civil Laws under the President of the Russian Federation, LL.D., Professor, Vavilin Evgeny V.
Published: April 2024

The article reviews some problems of the regulation of relations in the sphere of usage of highly-automated (unmanned) vehicles in the Russian Federation. The paper justifies the author’s view on the establishment of the system of fair distribution of liability of parties to the relations and the development of insurance in this sphere.
THE PROBLEM OF THE DETERMINATION OF THE LEGAL REGIME OF SUBSOIL USE WASTE
Authors:   Associate Professor of the Department of Civil Law of the Novosibirsk Military Institute Named after General of the Army I.K. Yakovlev of National Guard Troops of the Russian Federation, Associate Professor of the Department of Civil and Legal Disciplines of the Siberian Transport University, PhD (Law), Associate Professor, Proschalygin Roman A.
Published: April 2024

The article provides a brief analysis of the problem of determining the legal regime for subsoil use waste. During the study of this problem, contradictions and fragmentation of legal regulations were identified, giving rise to competition between legislation on subsoil and production and consumption waste in terms of consolidating the legal regime of subsoil waste. Based on the analysis of doctrinal sources, judicial practice and relevant rules of law, in order to determine the legal regime of objects arising during the implementation of mining activities, the need was identified for the mandatory conduct by the subsoil user of a comprehensive geological and economic assessment of these objects. As a result of the study, recommendations were proposed for making changes and additions to the norms of current legislation regulating the analyzed social relations, allowing to solve the identified problem.
Evolution of Legal Education and Science from the Exhibition Perspective: Values and Research Opportunities
Authors:   Head of the Department of History of State and Law, Director of the Historical Museum of the Ural State Law University Named after V.F. Yakovlev, PhD (Law), Associate Professor, Zipunnikova Natalya N.
Published: April 2024

The article emphasizes the exhibition phenomenon, its value potential in understanding the history of training legal personnel and jurisprudence. The opportunities and meaning of museum and other exhibition activities are shown on the example of a given law higher education institution.
Genesis of Laws on the Structure of Jury Trials in Post-Soviet Russia and Problems of Assuring Their Constitutional Nature
Authors:   Teaching Assistant of the Department of Criminal Law of the Astrakhan State University, Attorney at the Astrakhan Regional Bar Association, Tutarinova Natalya N.
Published: April 2024

The article examines the process of development of legislation on the organization of jury trials in post-Soviet Russia, and also touches upon the problems of ensuring compliance of this legislation with the Constitution of the country. According to the author, as a result of constitutional amendments, before the constitutional reform of 1993, the legislator thought or assumed a wider introduction into socio-political practice of the institution of trial with the participation of jurors, and civil cases were even placed in first place by the Constitution compared to criminal cases. The Constitution of the RSFSR still supported the construction of “professional justice together with people’s assessors”, but was aimed at a major transformation of democratic forms of justice in the future.
What Do the Game Theory and Rationality of the Plato’s Political and Legal Doctrine Have in Common?
Authors:   Head of the Division of Financial, Banking and Investment Laws of the Legal Department of the Ministry of Economic Development of the Russian Federation, PhD (Law), Kolosov Igor V.
Published: April 2024

In the Republic, Plato presents an ideal social system that arises on the basis of acting together for the purposes of meeting the neetheir own interests. The rationalistic orientation dominates in Plato’s political and legal thought; it consists in the fact that, under the guidance of reason, the individual performs actions aimed at achieving happiness. From the point of view of game theory, in the same way, each subject of law strives to achieve the most profitable result and realize their own interests at the lowest cost. Thus, there is reason to believe that the theory of games in law arose as a natural result of the development of the philosophical concept of rationality. The Plato political and legal thought in this regard require detailed analysis, since it, like modern game theory, combine assumptions about the achievement of individual interests and bounded rationality. Taking into account the similarity of the fundamental premises, the subject of this article is relevant and significant not only in historical and theoretical terms, but for modern jurisprudence.
Contribución del modelo praxeológico en las competencias ciudadanas de la educación superior
Authors: Bernate Jayson andrey , Puerto Garavito Sandra Consuelo
Published: April 2024

La presente reflexión surge del temario central en la tesis doctoral de la Universidad Metropolitana de Educación, Ciencia y Tecnología, UMECIT el cual pretende describir el impacto que tiene la praxeología en el desarrollo de las competencias ciudadanas en la educación superior, ilustrando aspectos de responsabilidad social, investigación formativa, pruebas Saber Pro, formación de licenciados y criterios curriculares en UNIMINUTO; relacionándose directamente con los dos temas centrales. La metodología desarrollada es cualitativa-reflexiva. De este modo, se identifican aportes significativos del modelo praxeológico teniendo en cuenta su forma de aplicación en cada fase, además de las herramientas que brinda mediante la relación entre teoría y praxis, la sistematización de experiencias y la visión social que proyecta. En conclusión, a partir de esta reflexión académica, el modelo praxeológico aporta e impacta positivamente al desarrollo de competencias ciudadanas debido a su método integral de formación, aunque se encuentran algunas problemáticas y necesidades respecto al eje central estudiado, que más que problemas, son retos para quienes son docentes y estudiantes que desarrollan su quehacer bajo la metodología de la praxeología.