bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of the Islamic Leadership Model in Educational Administration at Madrasah Ibtidaiyah
Authors: Hamdanah Hamdanah , Sholihah Mar’atus
Published: May 2023

Madrasah Ibtidaiyah, as an educational institution at the basic level, needs to manage its educational administration to create education that follows the direction of educational goals. Educational administration is necessary to achieve the quality of education; this case must be connected to the role of the madrasah ibtidaiyah principal as a leader in managing the educational administration. Islamic leadership model must be applied so that the implementation of educational administration in madrasah can run as it is supposed to. This study aimed to describe the implementation of the Islamic leadership model as educational administration can increase madrasah ibtidaiyah administration based on Islamic principles, which can establish Islamic education administration well. This research was conducted in descriptive qualitative approaches with research techniques by interviewing school principals and teacher boards to explore the management of Islamic leadership in the madrasah. Observation and documentation were also carried out at Madrasah Ibtidaiyah Al-Ma’arif 02 Jombang, Jember Regency. The results of this study show that the characteristics of the Islamic leadership model in education administration at Madrasah Ibtidaiyah of Al-Ma’arif 02 Jombang-Jember, including justice, amanah, fathonah, tabligh, shiddiq, qona’ah, siasah, and patience. Implementing the Islamic leadership model through educational administration can shape Islamic leadership characters for educators in madrasah ibtidaiyah and harmonize teachers and administrators in school to achieve educational goals.
UNLOCKING THE ARCHITECTURE OF THE COLONIZATION WINDOW: ICHNOFABRICS FROM UPPER CRETACEOUS TIDE-INFLUENCED MEANDER-LOOP DEPOSITS
Authors: DÍEZ-CANSECO DAVINIA , BUATOIS LUIS A. , MÁNGANO M. GABRIELA , CUEVAS-GONZÁLEZ JAIME , BENITO M. ISABEL
Published: May 2023

Studies dealing with the colonization window typically emphasize two major features: duration (short term vs. long term) and frequency of colonization (episodic vs. continuous). However, our understanding of tide-influenced meander loops requires consideration of an additional feature, the architecture of the colonization window, which comprises not only the spatial dimension and geometry of the colonization surface, but also its evolution through time. Tide-influenced meander-loop systems show a heterogeneous trace-fossil distribution that reflects the variety of processes operating along the point-bar and overbank colonization surfaces. Ichnofabric analysis of tide-influenced meander-loop deposits from the Upper Cretaceous Tremp Formation (Pyrenees, Spain) provides valuable insights into the sedimentary and ichnological dynamics of these marginal-marine systems and allows the importance of stratal geometry controlling the colonization window to be evaluated. Six ichnofabrics are identified in point bars and associated overbank deposits. These ichnofabrics differ in bioturbation index (e.g., higher in the upper part than the lower-middle parts of point bars), preservation of primary sedimentary fabric (typically preserved in the lower-middle parts of point bars), inferred behavior and trophic types (e.g., dominance of dwelling or feeding structures in the lower-middle and upper parts of point bars, respectively), and other features such as depth of penetration, ichnotaxonomic composition, presence or absence of root trace fossils and/or mottling, or number of superimposed suites. The key environmental factor controlling the nature and distribution of ichnofabrics is the morphology of the point-bar lateral-accretion surfaces and their evolution through time. The architecture of the colonization window is here linked to the helicoidal flow and discharge changes in meandering channels, and the successive development of lateral accretion units with time.
Digital Culture and Individuals: (Analysis of the influence of digital culture on individuals)
Authors: Aprilia Ruli
Published: May 2023

The public sphere in the internet age is shaped by changes in traditional information consumption practices. With the rise of social media and other online platforms, the ways in which people access and consume information have shifted significantly. One major change is the increased role of user participation in shaping the public sphere. The online users are forced to act and participate. Currently media users are active and looking for information. The World Wide Web is a giant external memory, capable of storing a lot of information. Data can be by all. Even if the use of books for five centuries made linear thinking the primary means of reasoning, now it is gradually replaced by multitask, nonlinear, more thinking faster, more fluid and shallower at the same time. Internet users who relying on this external memory has better data analysis capacity, but does not have more synthesis capacity. External memory in the world wide web becomes "Source of amnesia" citizens: they know the information, but they forget sources (and consequently they do not question the credibility of sources). This forms the practice of consuming and producing people's information in virtual public spaces. The purpose of this paper is to find out how educated young adults consume and generate information in virtual space
Transgender In Achieving The Social Acceptability In Pematangsiantar
Authors: Siburian Donny Paskah Martianus , Daulay Harmona , SBP Simanjuntak Junjungan , Ismail Rizabuana , Munthe Hadriana Marhaeni
Published: May 2023

Society expects men to behave in a masculine manner and fulfill traditional male roles, while women are expected to behave in a feminine manner and exhibit normal heterosexual behavior, such as engaging in sexual relations with the opposite sex. The existence of transgender individuals in society is often perceived as deviant. The purpose of this research is to examine the community's stereotypes towards transgender individuals in Pematangsiantar City and the adaptation strategies implemented by transgender individuals who are accepted in society. This research employs a mixed-method approach, with a focus on qualitative data analysis supplemented by quantitative data. The results of this study indicate that various negative stereotypes are associated with transgender individuals in Pematangsiantar City. Consequently, transgender individuals must use various strategies and make efforts to adapt and be accepted as themselves and as members of society. This research can serve as a reference for addressing social life and social status as a transgender individual amidst society.
The Influence Of Celebrity Endorsers And Electronic Word Of Mouth On Purchase Decision Trust On Lazada Marketplace Surabaya
Authors: Mandasari Fidela , Purwanto Eko , Purwanto Sugeng
Published: May 2023

Celebrity endorsers and electronic word of mouth are essential factors in creating trust and consumer purchase decisions for Lazada. Therefore, this study aims to determine whether celebrity endorsers and electronic word-of-mouth marketing can influence a consumer's purchase decision directly or through trust. The type of data used in this study is quantitative data. The sampling technique used in this study was nonprobability sampling with the purposive sampling method. Thus the sample used was 102 Lazada marketplace customers in Surabaya. The data analysis technique used to process data is SmartPLS. The results of this study show that Celebrity endorsers and Electronic word of mouth have a positive and significant effect on purchase decisions. Furthermore, Celebrity Endorsers and Electronic word of mouth positively and significantly affect purchase decisions through trust
The Effect Of Service Quality And Price Perception On Repurchase Intention Through Customer Satisfaction Citilink Juanda Airport Surabaya
Authors: Khuzaifah Hilda , Hendrati Ignatia Martha , Purwanto Sugeng
Published: May 2023

This study aims to test the effect of service quality and price perception on repurchase intentions through customer satisfaction as an intervening variable at Juanda Airport Surabaya for Citilink airlines. This research is descriptive and quantitative using SEM-PLS analysis tool with the help of Smart-PLS software. The data consisted of primary data collected from 102 respondents using accidental sampling to determine the sample. The results show that the quality of service has a tremendously positive influence on repurchase interest, but price perception has no significant effect. Customer satisfaction influences an intervening variable between service quality and repurchase intent but does not exist as an intervening variable between price perception and repurchase intent. Based on the historical background discussed and in comparison with the results of previous studies, this study attempts to examine the relationship among service quality, customer satisfaction, price perception, and repurchase interest of Citilink Airlines located at Juanda Airport in Surabaya. Taking case studies at this airport is because Juanda Airport is the main base of Citilink airlines and is one of the main airports with a relatively high passenger density in Indonesia.
An Analysis of Grammatical Error in Justin Bieber's Song Lyrics
Authors: Julieta Alin Hera
Published: May 2023

ABSTRACTA language is a communication tool used by every human being in everyday life. People used their language to communicate with each other to help deliver the information. Meanwhile, Indonesians lack grammar, especially to studying from unreliable sources, such as listening to songs. This research is trying to analyze the grammatical error in Justin Bieber’s song lyrics and identify the most frequent type of errors found in Justin Bieber’s song lyrics. This is descriptive qualitative research and the data instrument used in this research is data analysis. The result shows that there were three types of grammatical errors contained in Justin Bieber's song lyrics, such as Subject-Verb Agreement, Indefinite Pronouns, and Prepositions. The grammatical error contains 7 grammatical errors found in the subject-verb agreement, 5 grammatical errors found in the Indefinite Pronouns, and 1 grammatical error found in the preposition. However, the subject-verb agreement is the most frequent grammatical error used in Justin Bieber’s song lyrics.Keywords: Grammatical Error, Justin Bieber’s Songs, Lyrics
Formative Peer-Assessment in Oral Presentation Skill: EFL Secondary School Students’ Perception and Its Challenges
Authors: Widodo Jalu Wintang , Chakim Nur
Published: May 2023

Penilaian teman sebaya formatif memiliki peran penting dalam memantau performa belajar peserta didik di kelas. Dalam Kurikulum Merdeka Belajar, penilaian teman sebaya formatif adalah sebuah metode penilaian yang efektif untuk meningkatkan kemampuan kognitif, psikomotor, dan afektif peserta didik. Penelitian ini bertujuan untuk menelusuri persepsi dan tantangan yang dihadapi peserta didik SMP dalam menerapkan penilaian teman sebaya formatif selama kegiatan presentasi lisan. Penelitian ini menggunakan metode kualitatif dan dilakukan dengan melibatkan 5 peserta didik kelas VII di salah satu SMP di Sidoarjo. Data penelitian ini dikumpulkan dengan menggunakan kuesioner terbuka dan sesi wawancara. Sumber data penelitian diambil dari jawaban peserta didik yang ada di kuesioner dan wawancara. Analisis data digunakan sebagai evaluasi dari implementasi penilaian teman sebaya formatif dalam presentasi lisan di tingkat SMP. Penelitian ini menunjukkan bahwa penilaian teman sebaya formatif membantu peserta didik SMP dalam mempersiapkan tugas, fokus selama sesi kegiatan presentasi lisan, meningkatkan kemampuan berpikir kritis dan evaluatif, mengembangkan kepercayaan diri, dan mengenali kelebihan dan kelemahan teman mereka secara mendalam. Di sisi lain, beberapa peserta didik justru mendapatkan keluhan, menemukan kesulitan dalam menentukan nilai, ulasan, dan pertanyaan yang sesuai serta menemukan adanya tindakan kecurangan selama kegiatan penilaian teman sebaya formatif. Selain dari keuntungan dan kerugiannya, penilaian teman sebaya formatif dapat dipertimbangkan sebagai metode penilaian alternatif bagi para peserta didik SMP selama melaksanakan kegiatan presentasi lisan. Diharapkan, penelitian ini dapat dikembangkan oleh peneliti lain di lingkup pendidikan yang lebih luas.
The Portrayal of Married Woman’s Life in Zemindar’s Wife by Qaisra Shahraz
Authors: Roifah Miftahur
Published: May 2023

Marriage is a social institution that adopts a patriarchal ideology to regulate the relationship between husband and wife. As a result, conflicts based on gender inequality can arise as patriarchal ideologies in marriage reinforce the dominance of men over women. A married woman’s life is often portrayed in feminist literature, such as in the short story of Qaisra Shahraz, Zemindar’s wife. This study analyzes the married life of Noor by applying the theory of Simone De Beauvoir in her book, The Second Sex. Besides, the study uses a qualitative approach with a close reading method. The results show that the short story Zemindar's Wife depicts the unequal gender relationship between husbands and wives in marriage. This gender imbalance leads to inequality, with women being dominated and subordinated by their husbands.
WOMEN’S LANGUAGE FEATURES IN THE PODCAST STORIES OF THE SOUL
Authors: Suhesty Ayu , Sriyono Sriyono
Published: May 2023

This study aims at determining the women’s language features produced by Najwa Zebian in the podcast Stories of The Souls and its functions of women’s language. This research utilized a descriptive qualitative method to analyze the data. Data were utterances produced by Najwa Zebian indicating women language’s features. The findings of this research revealed that Najwa did not use all of the women’s language features in the podcast Stories of The Soul. The study identified nine women’s language features occurred, such as lexical hedges or fillers, tag questions, rising intonation , hypercorrect grammar , intensifiers as the most dominant used by Najwa in the podcasts, super polite forms , empty adjectives , avoidance of strong swear words , and emphatic stress . However, the result did not give the occurrence of precise color terms. This study also found several functions of women’s language features. All of the functions are applied to the features in the podcast, including expressing uncertainty, starting a discussion, expressing feelings, and softening an utterance.
Bipolar valued probabilistic hesitant fuzzy sets based on Generalized Hybrid Operators in multi-criteria decision making problems based TOPSIS
Authors: özlü şerif
Published: May 2023

This paper aims to present some novel ordering methods to obtained Bipolar valued probabilistic hesitant fuzzy sets (BVPHFS) by extending probabilistic hesitant fuzzy sets (PHFS). PHFS is a strong version of hesitant fuzzy sets (HFS) in terms of evaluated as probabilistic of each element in HFS. Thus, this case proposes flexibility about selection of an element and aids to overcome with noise channels. Then, some properties of BVPHFS are surveyed. Further, some new aggregation operators are discussed called bipolar valued probabilistic hesitant fuzzy weighted average operator (BVPHFWA), Generalized bipolar valued probabilistic hesitant fuzzy weighted average operator (GBVPHFWA), bipolar valued probabilistic hesitant fuzzy weighted geometric operator (BVPHFWG), Generalized bipolar valued probabilistic hesitant fuzzy weighted geometric operator (GBVPHFWG), bipolar valued probabilistic hesitant fuzzy hybrid weighted arithmetic and geometric operator (BVPHFHWAG) and Generalized bipolar valued probabilistic hesitant fuzzy hybrid weighted arithmetic and geometric (GBVPHFHWAG) and some basic properties are presented. Moreover, two different algorithms are put forward with helping to TOPSIS method and by using aggregation operators over BVPHFSs. The validity of proposed operators are analyzed by proposing an example and results are compared in
their own.
Multiple Hypoxia-Independent Triggers of Upper Airway Long-Term Facilitation
Authors: Lui Simon , Tadjali Arash , Peever John
Published: May 2023

The respiratory control system can augment respiratory output following repetitive challenges. For example, repeated airway obstructions can trigger a form of respiratory memory that strengthens inspiratory activity of hypoglossal (XII) motoneurons. This augmentation in respiratory motor output is known as long-term facilitation (LTF) and can be elicited by repeated apneas or bouts of hypoxia. We demonstrate that LTF can be triggered in the absence of repeated apneas or hypoxia by intermittently stimulating locus coeruleus (LC) neurons, or through pharmacological activation of the neurotrophic machinery in XII motoneurons. We used pharmacological and optogenetic approaches to elicit LTF and show that this is mediated by α1-adrenergic receptor-binding at the XII motor pool. We also use optical LC inhibition to reaffirm the importance of the LC in mediating apnea-induced LTF. Lastly, we show that neurotrophic signaling agonists or antagonists applied to XII motoneurons can also be used to elicit or prevent LTF expression, respectively, and acts co-operatively with noradrenaline. These results suggest LTF can be triggered by multiple hypoxia-independent triggers and is mediated by the release of noradrenaline from the LC onto α1-adrenergic receptors on XII motoneurons to trigger plasticity via activation of neurotrophic signaling cascades.
Use of Routine Health Information Systems Data in Developing and Monitoring District and Facility Health Plans: A scoping review
Authors: Byrne Elaine , Heywood Arthur
Published: May 2023

Background:
Routine Health Information Systems data should be used in a systematic and institutionalised manner to support the making of plans, the monitoring of plans and in supportive supervision. To explore to what extent there is discussion about the linkage between planning, monitoring and supervision of sub-national programs using routine data we conducted a scoping review. The review question was: How are routine health information systems used or should be used in developing and monitoring health plans at district and facility level?
Methods:
From a search of Ovid Medline (all), EMBASE and Web of Science along with a review of grey literature and involving a number of key stakeholders in reviewing and identifying any missing resources a total of over 2200 documents were reviewed and data from 13 documents were extracted.
Results:
Overall, there are many descriptions of how to implement and strengthen systems, ways to assess and improve data availability and quality, tools to improve the data use context, training in data use and mechanisms to involve stakeholders and strengthen infrastructure. However, there are massive gaps in relation to good use cases or examples of where routine health data is used in the development, monitoring and supervision of plans at district and facility level.
Conclusions:
There appears to be no institutionalised obligation of planners to monitor plans, very little guidance on how to practically monitor programs and minimal discussion about how to use the routinely available data to supportively supervise the implementation of the plans.
To overcome these shortcomings, we recommend that practical procedures to ensure linkage of existing district plans to regular monitoring of priority programs are institutionalised, that mechanisms for making managers institutionally accountable for monitoring and supervising these plans are put in place, and that practical guidelines for linking plans with RHIS data and regular monitoring and supportive supervision are developed.
Prevalence, Trends, and Associated Factors of Hypertensive Crisis in Peruvian Adults, 2014-2019
Authors: Ocon Victor Calderon , Peredo Fiorella Cueva , Bernabé-Ortiz Antonio
Published: May 2023

Objectives:To determine the prevalence and trend over time of the hypertensive crisis, as well as sociodemographic and behavioral factors associated with it in Peruvian adults.Materials and methods:Cross-sectional analysis of the Demographic and Family Health Survey (ENDES) from 2014 to 2019. The dependent variable was hypertensive status, with three categories: normotensive, hypertensive, and those with hypertensive crisis (CH). HC was defined as systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg. Associated variables of interest were evaluated using multinomial logistic regression, and the trend of HC was assessed using the Cochrane-Armitage test.Results:A total of 166,741 participants were analyzed, mean age 43.5 (± 16.4) years, 54.4% were women, and 75.5% came from urban areas. The prevalence of hypertensive crisis was 1.3% (95% CI: 1.2% - 1.4%), and this estimate decreased from 1.6% in 2014 to 1.1% in 2019 (p< 0.001). Cases of hypertensive crises were more frequent in older individuals, especially those aged 60+ (OR = 80.6), males (OR = 1.43), urban residents (OR = 1.25), overweight (OR 1.65) or obese (OR = 2.41) and having diabetes (OR = 2.22).Conclusions:The presence of hypertensive crisis was relatively common in the general Peruvian population. There is a need to improve the strategies for diagnosis, treatment, and control of hypertension in our context to reduce the cases of hypertensive crisis.
Using Deep Learning Models to Predict the Risk of Peripheral Neuropathy on Diabetic Patients
Authors: Lee Tsair-Fwu , Chiu Chi-Min , Tseng Chin-Dar , Huang Hong-Zhi , Lin Chih-Hsueh , Lin Guang-Zhi , Lee Shen-Hao , Yang Jack , Lin Kun-Der
Published: May 2023

To establish a suitable deep learning model in order to predict the risk of diabetic Peripheral Neuropathy (DPN) by using fundus photography images of type II diabetic patients with artificial intelligence (AI) approach. From the year 2013 to 2017, by using a diabetes care database established by the Department of Endocrinology and Metabolism of Kaohsiung Datong Hospital (KMTTH) and the Affiliated Hospital of Kaohsiung Medical University (KMUH), a corresponding retrospective study of fundus photographic images of patients with type II diabetes mellitus was performed. Patients with Type II diabetes who have undergone clinical routine treatment and have routine ophthalmoscopy were analyzed and classified according to the results of the Nerve Conduction Velocity (NCV) method. Soon after the patient's personal information was removed, the image is preprocessed by adaptive histogram equalization (CLAHE) to limit the contrast variation. These preprocessed images were then divided into training, validation, and test sets. Another two sets of Rotated image data were also incorporated for enhancements to build prediction models through four deep learning architectures: InceptionNet, VGGNet, ResNet, and ConvMixer DPN model, respectively. In this study, a classification model for predicting the severity of DPN was successfully established through four deep learning architectures. The accuracies of the four DPN prediction models established in this study were 0.94, 0.90, 0.97, and 0.96; AUC values have achieved at 0.92, 0.93, 0.95, and 0.96; specificity analyses were 1.00, 0.92, 1.00, and 0.98; The combined sensitivity values of mild and moderate to severe DPN reached 0.84, 0.90, 0.90, and 0.92, respectively. An AI-assisted diagnostic model was successfully established to predict the severity of diabetic peripheral neuropathy (DPN), which could determine whether the patient has DPN from the retinal fundus images obtained after ophthalmoscopy and with its associated severity; therefore, it is an efficient, non-invasive method of DPN detection.
Global, regional and national burden of human cystic echinococcosis from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019
Authors: Miao Li-yuan , Tian Tian , Wang Wei , Zhou Xiao-Nong
Published: May 2023

Background: Cystic echinococcosis (CE) is a neglected tropical parasitic disease that poses huge disease, social and economic burdens in the world. Although great strides have been achieved, multiple challenges remain to achieve the ambitious goal targeting CE set in the WHO roadmap for neglected tropical diseases 2021–2030. Estimates of the disease burden due to CE facilitate the progress towards eliminations; however, there is little knowledge on global morbidity, mortality and disability-adjusted life years (DALYs) of CE until now. This study aimed to present the most up-to-date data about the global, regional and national disease burden due to CE from 1990 to 2019 and to project trends in the next 10 years.
Methods: We measured the global, regional and national morbidity, mortality and DALYs of CE from 1990 to 2019 based on the Global Burden of Disease Study 2019 (GBD 2019) data, and we examined the correlation between socioeconomic development levels and the disease burden of CE. In addition, the disease burden due to CE was projected using Bayesian age-period-cohort analysis with integrated nested Laplace approximations from 2020 to 2030.
Results: The global number of CE cases increased from 134,980 [95% uncertainty interval (UI): (93,141 to 195,144)] in 1990 to 207,368 [95% UI: (6,347,183 to 8,769,520)] in 2019 [estimated annual percentage change (EAPC) = 0.54], and the age-standardized incidence rate (ASIR) of CE reduced from 2.65/105 [95% UI: (1.87/105 to 3.7/105)] in 1990 to 2.6/105 [95% UI: (1.72/105 to 3.79/105)] in 2019 (EAPC = ‒0.18). The number of deaths, DALYs, age-standardized mortality rate (ASMR) and age-standardized DALYs rate due to CE all appeared a tendency towards a decline from 1990 to 2019. A higher disease burden of CE was measured in women than in men in 2019. There was a significant difference in ASMR of CE in regions specified by socio-demographic index (SDI) and lower burdens of CE were estimated in high SDI regions. The global ASIR of CE was projected to appear a tendency towards a decline from 2020 to 2030; however, the ASMR and age-standardized DALY rate were projected to rise.
Conclusions: Our data may provide data-based evidence for public health officials and policy-makers to formulate and implement cost-benefit interventions to tackle the disease burden attributable to CE. More health resources are recommended to be allocated to low SDI regions, women and the elderly at ages of 55 to 65 years to reduce the disease burden of CE.
A quantitative study to predict the risk of recurrence after radiotherapy for cervical cancer based on multi-sequence MRI imagingomics
Authors: Dai Zhenhuo , Lin Kaiwu , Lin Yuanrong , Chen Ya , Zheng Jiwei , Lin Li
Published: May 2023

Background With the increasing clinical application of radiomics,the ability of magnetic resonance imaging omics to diagnose and predict the prognosis of diseases has attracted extensive attention in the scientific research community, and its application in the diagnosis, staging and treatment efficacy evaluation of cervical cancer has been gradually got attention..Methods All 52 patients in the radiotherapy group were cervical cancer patients and were diagnosed and treated with radiotherapy at our hospital from July 2019 to December 2021, while the healthy control group was selected from 41 healthy patients. The MRI performance of the two groups and the MRI performance of the patients in the radiotherapy group before and after treatment were observed separately. In addition, their ADC values were compared and the changes in ADC values before and after treatment were compared in patients with different prognosis in the radiotherapy group, compared the texture analysis parameters of patients with and without postoperative recurrence in radiotherapy group, and analyzed the predictive efficacy of MRI texture analysis parameters on the recurrence of cervical cancer patients after radiotherapy by ROC.Results The inorganic mass and DWI values of patients with cervical cancer increased with their grading and ADC decreased with them; Comparing the ADC values before and after radiotherapy, it was found that the values in the radiotherapy group were obviously lower than those in the healthy group (P < 0.05); a total of 16 patients (30.77%) received radiotherapy, they had recurrence within 6 months after radiotherapy and 36 patients (69.23%) had no recurrence in the radiotherapy group; according to the recurrence of patients after radiotherapy. The ROC curve analysis showed that the area under the curve of entropy value was the largest, which confirmed its diagnostic effectiveness.Conclusion Multi-series MRI imaging omics is of high clinical value in predicting the risk of recurrence after radiotherapy for cervical cancer patients.
Peatland porewater chemistry reveals field redox ranges for specific decomposition processes
Authors: Boonman Jim , Harpenslager Sarah Faye , Dijk Gijs van , Hefting Mariet M. , Smolders Alfons J.P. , de Riet Bas van , Velde Ype van der
Published: May 2023

Peat decomposition, driven by soil metabolic processes, was responsible for 2% of the anthropogenic greenhouse gas emissions in 2019. The peat soil redox potential (Eh) and pH reflect the chemical state of the soil and the (biogeo)chemical processes that occur and are therefore linked to the rate of peat decomposition and greenhouse gas production. We related porewater chemistry (pH, NO3-, SO42-, Mn(II), Fe(II), S2- and CH4, >2000 samples) to continuous Eh measurements (2020-2022) from five agricultural drained peatland sites in the Netherlands that consist of measuring plots with and without subsoil irrigation and drainage (SSI) in order to establish Eh ranges that identify specific metabolic processes. We found that methanogenesis, reduction of SO42-, Fe(III), NO3-/ Mn(IV) and O2 occurred at Eh (at pH 5.5) of < -49 mV, -49 – 104 mV, 104- 364 mV, 364- 700 mV and >700mV respectively. Eh over depth and time closely followed temporal and spatial fluctuations in groundwater level and porewater chemistry, and revealed the extent of O2 intrusion and the occurrence of methanogenesis. Higher and more constant groundwater levels year-round tended to deplete porewater Fe(II) and SO42-, which led to more reducing Eh and higher porewater CH4 concentrations. These mechanistic insights help to optimize GHG mitigation strategies for drained peat regions.
Manoeuvre a Cross-Spectral Algorithm and Machine Learning Approach to Categorize Seizures
Authors: Ojo Stephen , Allabun Sarah , Shukla Prashant Kumar , Alqahtani Mohammed S. , Pareek Piyush Kumar , Abbas Mohamed , Wechtaisong Chitapong , Othman Manal , Soufiene Ben Othman
Published: May 2023

EEG signals are recordings of electrical activity in the brain, and they can be used to detect epileptic seizures. Cross-spectral analysis involves analyzing the spectral coherence between different frequency bands in EEG signals. Cross-spectral seizure detection is a technique used to detect seizures in electroencephalography (EEG) signals by analyzing the frequency content of the signal in different frequency bands. Spectral coherence is a measure of how correlated two signals are in the frequency domain, and it can be used to identify patterns in EEG signals that are characteristic of seizures. Even if the ECG, which provides a direct measure of heart rate, were polluted by noise or missing altogether, the heart rate computed from such signals would be erroneous. This necessitates the use of an accurate heart rate estimate, which is especially important when the ECG is noisy or missing. To put it another way, fusion combines cardiovascular data with no cardiovascular (NC) signals, which are not connected to cardiac activity but include signs of heartbeats. According to the results of our evaluation of standard datasets, they determined that the SSF-TKE approach is particularly successful at identifying R-peak artefacts in non-cardiovascular signals that ECG anomalies have contaminated. When tested on standard datasets, the beat SQI-based voting fusion technique demonstrated a high degree of accuracy in predicting heart rate from a fusion of multimodal information. Compared to the single signal technique, the fusion methodology out per-forms it when determining heart rate precision. This strategy was evaluated using ECG and ABP signals from a synthetic noise dataset, which was created by adding various forms of calibrated noise to clean signals and then testing the outcomes of the technique on those signals. As a result of our paper, we noticed that merging cardiovascular and no cardiovascular inputs increased the accuracy of physiological parameter assessment.
Challenges and opportunities: A case study from a European city shows the influence of biological work on bioaerosol formation from indoor biological wastewater treatment laboratory
Authors: Upadhyay Ruchi , Przystaś Wioletta , Gautam Sneha
Published: May 2023

Bioaerosol emitted in university biological laboratories may exert adversely effects on employees and students. The occupational health and safety have been given much importance. This study aimed to monitor the risk of bioaerosol formation inside a biological wastewater treatment laboratory where other biological activities were performed along with wastewater treatment using the biological method. A single-stage impactor performed the air sampling to study concentration of bacterial and fungal bioaerosols and the diversity of air microbiota also been assessed. In early winter, 2018 MPN/m3 bacterial aerosol concentrations were observed which correlated with an increased number of occupants and their experimental activity. In contrast, the fungal concentration was found below the upper permissible limits in indoor environments, and it was influenced by seasonal change and humidity and were not influenced by number of occupants. The more significant number of morphological types of bacteria and fungi indicated diversity of air microbial community. This result suggests a moderate risk of bacterial bioaerosol to occupants working in wastewater treatment laboratory.
Angioarchitectural features of arteriovenous fistulas of cranio-cervical junction predicting the risk of clinical presentation and unfavorable outcome: insight from a multicenter cohort and pooled analysis.
Authors: Li Zongze , Zhang Hongfei , Zhao Yang , Liu Peixi , Shi Yuan , Liu Mingjian , Quan Kai , Tian Yanlong , Li Peiliang , Zhao Yuanli , Zhu Wei
Published: May 2023

Objective Arteriovenous fistulas (AVFs) at the cranio-cervical junction (CCJ) are uncommon conditions with complex angioarchitecture. The objective of this study was to identify the angioarchitectural features of CCJ-AVF to predict the risk of clinical presentation.Methods The study population was comprised of 68 consecutive patients with CCJ-AVF at two neurosurgical centers between 2014 and 2022, and a systematic pooled analysis of 68 cases with detailed clinical data obtained via PubMed database from 1990 to 2022. Clinical and imaging data were collected to analyze factors for subarachnoid hemorrhage (SAH), myelopathy, and modified Rankin scale (mRS) at presentation.Results The mean age of the patients was 54.5 ± 13.1 years, and 76.5% of patients were male. The most common feeding arteries was V3-medial branches(33.1%), and drainage was frequently through the anterior or posterior spinal vein/perimedullary vein (72.8%). The most common presentation was SAH(49.3%), and an associated aneurysm (adjusted OR, 7.44; 95%CI, 2.89–19.15) was a risk factor for SAH. Anterior or posterior spinal vein/perimedullary vein (adjusted OR, 2.78; 95%CI, 1.00-7.72) and male gender (adjusted OR, 3.76; 95%CI, 1.23–11.53) were associated with higher risk for myelopathy. An mRS score ≤ 2 at presentation (adjusted OR, 0.25; 95%CI, 0.09–0.71) and an associated aneurysm (adjusted OR, 0.16; 95%CI, 0.06–0.43) were protective factors. Presentation with myelopathy (adjusted OR per score, 4.73; 95%CI, 1.31–17.12) was an independent risk factors for unfavorable neurological status in untreated CCJ-AVF.Conclusion This study identifies risk factors associated with SAH, myelopathy, and unfavorable neurological status at presentation in patients with CCJ-AVF. These findings may help guide management and treatment decisions for these complex vascular malformations.
AHUS mistaken for TTP associated with COVID-19: a case report
Authors: Wu An , Wang Jiaping , Shi Cong , Yan Xiao , Ouyang Guifang , Sheng Lixia
Published: May 2023

Thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS) are both thrombotic microangiopathies that share several clinical traits including microangiopathic hemolytic anemia, thrombocytopenia, and organic damage. There is inherent opportunity for misdiagnosis. As thrombocytopenia and thrombus are strongly related to COVID-19, it may be more difficult to tell an aHUS from a TTP when COVID-19 is present. Thus, we describe a patient presenting with severe COVID-19 who was misdiagnosed with TTP but in the end corrected to aHUS. We suggest that perform detection to ADAMTS-13 activity and complement gene mutation as soon as possible is necessary.
Toxoplasma gondii infection in pig intended for human consumption in Brazil: seroprevalence, risk factors and influence of Biosecurity Measures
Authors: Scofano Agostinho Sergio , Arruda Igor Falco , Teixeira Jessica Nogueira , Cunha Nathalie Costa , Nascimento Elmiro Rosendo , Amendoeira Maria Regina Reis , Millar Patrícia Riddell
Published: May 2023

Background: Toxoplasmosis, caused by Toxoplasma gondii, is a zoonotic disease highly prevalent in Brazil and poses considerable risk to public health. T. gondii is an obligate intracellular protozoan that is capable of infecting mammals and birds. In humans, the infection occurs mainly by the ingestion of raw or undercooked meat containing tissue cysts or other food items or water contaminated with sporulated oocysts, or by congenital transmission. Despite the prevalence of T. gondii in Brazil and its proven circulation among humans, animals, and the environment, there have been few studies on toxoplasmosis and its epidemiology.
Methods: Blood samples were collected from 416 pigs from 55 producer farms in 27 municipalities in the state of Espírito Santo, Brazil. An indirect immunofluorescent assay (IFA) was performed to estimate the seroprevalence of T. gondii and identify the associated risk factors.
Results: The T. gondii antibody prevalence rate in commercial swine herds from Espírito Santo was 15.4% (64/416), and the most frequent antibody titer was 1:64 (61/64) followed by 1:256 (3/64). Seropositivity for T. gondii was related to the presence of cats, existence of internal insulation fences on the farm, use of compost chambers on the farm, water sources, and the age of pigs.
Conclusions: To the best of our knowledge, this is the first study to report anti- T. gondii antibodies in the serum of pigs in the state of Espirito Santo, Brazil. This finding is important to public health because seropositive pigs can harbor tissue cysts in their meat, thereby representing a zoonotic risk for consumers of raw or undercooked porcine meat or its products.
Three Gorges Dam: Differential determinants and spatial-temporal effects of the change of snail density
Authors: Gong Yanfeng , Tong Yixin , Jiang Honglin , Xu Ning , Yin Jiangfan , Wang Jiamin , Huang Junhui , Chen Yue , Jiang Qingwu , Li Shizhu , Zhou Yibiao
Published: May 2023

BACKGROUND The abundance of Oncomelania hupensis snail can promote the transmission of schistosomiasis japonica. Snail distribution varies spatially and temporally in different geographical regions. Hence, we investigated differential drivers of snail density between the downstream and upstream areas of Three Gorges Dam (TGD), and spatial-temporal changes in snail abundance.METHODS We deployed the snail survey at 200 sites over 5 years to monitor a dynamic change in snail abundance within the Yangtze River basin. Corresponding variables that might affect snail abundance, such as Meteorology, vegetation, terrain, and economy, were collected from multiple data sources. We conducted the Bayesian spatial-temporal modeling framework to investigate the differential determinants and spatial-temporal effects of the change of snail density.RESULTS Obvious volatility for snail density was detected in the downstream area of TGD, whilst a small increment in the upstream area. For the downstream area of TGD, Snail density was positively associated with the average minimum temperature in January of the same year, annual normalized difference vegetation index of the previous year (NDVI), the 2nd quartile of average annual relative humidity of the previous year (RH), the 3rd quartile of RH, the 4th quartile of RH. Snail density was negatively associated with the average maximum temperature in July of the previous year, and annual night-time light of the previous year. An approximately inverted “U” curve of relative risk was detected among sites with a greater average annual ground surface temperature of the previous year. For the upstream area, snail density was positively associated with NDVI, the 2nd quartile of total precipitation of the previous year (Pre), the 3rd quartile of Pre, and the 4th quartile of Pre. Snail density was negatively associated with Slope.CONCLUSIONS Collectively, our study demonstrated a rebound in snail density between 2015 and 2019. In particular, temperature, humidity, vegetation, and human activity were the main drivers affecting the snail abundance in the downstream area of TGD, while precipitation, slope, and vegetation were the main drivers affecting the upstream snail abundance. This evidence can assist the authorities to execute more precise strategies for snail investigation and control.
Systematic comparison of variant calling pipelines of target genome sequencing cross multiple next-generation sequencers
Authors: Feng Baosheng , Lai Juan , Fan Xue , Guo Xin , Liu Yongfeng , Wang Miao , Wu Ping , Zhou Zhiliang , Yan Qin , Sun Lei
Published: May 2023

BackgroundTargeted genomic sequencing (TS) greatly benefits precision oncology by rapidly detecting genetic variations with better accuracy and sensitivity owing to its high sequencing depth. Multiple sequencing platforms and variant calling tools are available for TS, making it excruciating for researchers to choose. Therefore, benchmarking study across different platforms and pipelines available for TS is imperative. In this study, we performed a TSof Reference OncoSpan FFPE (HD832) sample enriched by TSO500 panel using four commercially available sequencers, and analyzed the output 50 datasets using five commonly-used bioinformatics pipelines. We systematically investigated the sequencing quality and variant detection sensitivity, expecting to provide optimal recommendations for future research.ResultsFour sequencing platforms returned highly concordant results in terms of base quality (Q20>94%), sequencing coverage (>97%) and depth (>2000×). Benchmarking revealed good concordance of variant calling across different platforms and pipelines, among which, FASTASeq 300 platform showed the highest sensitivity (100%) in high-confidence variants calling when analyzed by SNVer and VarScan 2 algorithms. Furthermore, this sequencer demonstrated the shortest sequencing time (~21 hr) at the sequencing mode PE150. Through the intersection of 50 datasets generated in this study, we recommended a novel set of variant genes outside the truth set published by HD832, expecting to replenish HD832 for future research of tumor variant diagnosis. Considering the dissimilarity of variant calls across different pipelines for datasets from the same platform, we recommended an integration of multiple tools to improve variant calling sensitivity and accuracy for the cancer genome.ConclusionsIllumina and GeneMind technologies can be used independently or together by public health laboratories performing tumor TS. FASTASeq 300 platform performs better regarding variant detection sensitivity under SNVer and VarScan 2 algorithms along with the shortest turnaround time. Our study provides a standardized target sequencing resource to benchmark new bioinformatics protocols and sequencing platforms.
Effect of nutrient stock solutions on the growth and yield of apical rooted cutting (Solanum tuberosum L.) varieties in a hydroponic system
Authors: Wambugu Winnie Chebet , Opiyo Arnold M. , Kibe Anthony M.
Published: May 2023

There is limited information on adequate application rates of nutrient stock solutions in hydroponic seed potato production systems in Kenya. This has led to low yields of apical rooted cuttings (ARC) potato varieties due to either nutrient deficiencies or toxicities. This study evaluated the effects of varied nutrient stock solution concentrations (NSSC) on the growth and yield of potato apical rooted cuttings varieties. Two greenhouse experiments were conducted at the Climate and Water Smart Agriculture Centre of Egerton University, Kenya. The experiments were laid out in a split-plot of a randomized complete block design, where the main plot comprised three nutrient concentrations, i.e., 75% (N75), 100% (N100) and 125% (N125) of the ADC-Molo’ nutrient formulation. The subplots were allocated the four potato varieties (Shangi, Wanjiku, Nyota and Unica). The results revealed significant (p ≤ 0.05) effects of NSSC application rates on the growth and yield attributes of ARCs. The N125 gave the tallest plants, highest normalised difference vegetation index (NDVI), plant survival rate and fresh and dry matter (DM %) yields of aboveground biomass (AGB) in both experiments. Nyota produced taller plants, and gave higher NDVI values, higher fresh and DM weight of AGB. The highest numbers of minitubers/plant (8.67 to 9.93) as well as yields (9.97-13.08t/ha) were observed under 125% NSSC in both experiments. Nyota variety gave the highest minitubers/plant while Unica gave the highest yield. Therefore, to achieve high growth and yields of ARCs under a hydroponic system, seed potato producers should use 125% of the ADC Molo nutrient formulation.
Utilization of Crumb Rubber as Partial Replament of Fine Aggregate With Crumb Rubber
Authors: REDDY B L NIRANJAN , ARSHAD K , DEVAKI P , FAHEEM S , DHARANI G V
Published: May 2023

Tyre manufacturing is increasing globally as a result of the expansion of the automobile industry, but as landfill space is becoming less and less available, it is becoming increasingly difficult to dispose of the waste tyres. Aggregate and cement are the two primary materials needed in the construction of buildings using concrete. The effectiveness of recycled crumb rubber as a partial replacement for fine particles in concrete mix at various percentages, as well as its impact on concrete parameter like compressive strength, split tensile strength, and flexural strength, were examined in this study.
The waste crumb rubber particles were used to replace fine aggregates in concrete at ratios of 0%, 5%, 10%, 15%, 20%, 25% in M30 grade concrete. Testing was done on the crumb rubber, and after analysing its properties and comparing them to fine aggregate, it was suggested that maximum.
Percentage of rubber crumbs, and after analysing its properties and comparing them to fine aggregate, it was suggested that maximum percentage of rubber crumbs making it best suited for non- structural loading applications.