bluuebunny/crossref_metadata_2025 huggingface dataset:
Modeling an Intelligent Framework for Optimizing UAV Path Planning and Anti-collision in Agriculture
Authors: Rao V Vijaya Chandra , M P Karthikeyan , Savita Dr , Kumar N Venkata Sairam , Bhalla Anubhav , Swarup Lakshya
Published: February 2025

Unmanned aerial vehicles (UAV) are increasingly utilized for monitor expansive farming to their effectiveness in observation and data gathered. Efficient path planning and collision prevention are critical for optimizing UAV operation in such settings. The efficiency can be controlled by the quality and declaration of UAV sensed data, as well as the difficulty of real world ecological variables that could impact path optimization and collision prevention. This research introduce a novel technique, the customizable dung beetle search tuned random forest (CDBS-RF) method, designed to improve UAV route planning. The CDBS-RF method integrated the dung beetle search (DBS) algorithm, known for its robust optimization capabilities, with random forest (RF) to enhance optimal path security and effectiveness. This method dynamically adjusts path safety and effectiveness. This approach dynamically adjusts path planning parameter to make sure optimal route selection and collision prevention. The suggested technique was evaluated utilizing UAV-sensed data and implement in python based virtual environment. Experimental consequences demonstrate that the CDBS-RF approach considerably enhances UAV path planning performance, provide safer and more efficient navigation for self and more efficient navigation for self-sufficient tarp monitoring. The performance evaluation techniques include the planning time (0.789) and path length (21.526). By utilize advanced optimization and anti-collision algorithms, this technique offer a promising solution for improving UAV operations in agricultural surveillance.
The Edge Computing Extensive Data Processing Framework and Algorithm for the Internet of Things
Authors: Ge Luyao
Published: February 2025

The paper studies a monitoring pedestrian recognition method driven by big data for edge-cloud collaboration. It extends the original centralized computing to edge and cloud collaborative processing. Firstly, the image boundary node N0 is preprocessed, and the extracted image is expressed in multiple levels. Then, the RGB-D multimodal image learning modeling method is applied to the edge nodes of the network using cloud computing. The boundary node uses the existing learning mode to perform action identification and uploads the identified action information to the cloud to form the final action classification. The method of bone surface fitting and dense trajectories is combined to achieve robust, dense human posture feature extraction. The directed principal component histograms of 3D stereo structures are obtained using dense point cloud data. The features of the spatial and temporal neighborhood 3D gradient histogram are extracted from the apparent texture. Through experiments, it is verified that the proposed method can significantly reduce the shortcomings of traditional centralized algorithms in data transmission and cloud storage and improve the pattern recognition accuracy by 2.2\% based on edge cloud collaboration.
Carbon Emission Prediction and Sensitivity Evaluation of Virtual Power Plants Based on Big Data and Multiscale Analysis
Authors: Li Jie , Yang Zhou , Jiang Wenqian , Pan Juntao
Published: February 2025

In order to address the issue of increased prediction errors in the peak carbon emissions of virtual power plants due to various influencing factors of electricity carbon emissions, the authors propose a study on the prediction and sensitivity evaluation of virtual power plant carbon emissions based on big data and multi-scale analysis. Firstly, it analyzes the original data sequence and cumulative sequence, use grey BP neural network to construct a carbon emission peak prediction model, then it analyzes the factors affecting electricity carbon emissions, and use recursive calculation method to calculate electricity carbon emissions. Then, it compress the model coefficients to zero through a penalty function and filter out significant variables. Based on the adjacency characteristics of carbon emission flow, the node carbon potential is calculated through finite recursion, and iterative training is carried out within the allowable error range to solve the model and obtain the predicted peak carbon emissions of electricity. The experimental results indicate that the prediction results of the designed method under three scenarios of benchmark setting, low-carbon, and enhanced low-carbon are 40 million tons, 390 million tons, and 40 million tons, respectively, which are consistent with the actual results, indicating that the prediction error of this method is lower and the prediction results are more accurate. The method studied by the authors can provide technical support for carbon emission control and improve prediction accuracy.
Asset Management of Smart Grid using Digital Twin Technology and Machine Learning Algorithms
Authors: Deng Xiaotao
Published: February 2025

In order to solve the problem of data insecurity in the current smart grid asset monitoring and management platform, the author proposes a research on smart grid asset management using digital twin technology and machine learning algorithms. This study achieves data security performance verification and monitoring through the application of data consensus mechanism. When verifying data in data nodes, data regulation verification information can be published in the form of a set of data packets to the data chain. The best node in the node is used as the data packet in the blockchain to build a platform structure. Management is achieved through data encryption, data monitoring, and device status classification. The experimental results show that the data theft rate simulated using this method has been reduced by 25.48%, and the security performance of the scheme is higher. The use of digital twin technology and machine learning algorithms for smart grid asset management has improved the security issues existing in traditional solutions and has enormous potential for application.
A Precise Health Follow-up Management Information System for Community Chronic Diseases based on Big Data Analysis
Authors: Miao Qingtian
Published: February 2025

To enhance the efficiency of medical big data utilization, the author introduces a study on a precise health follow-up management information system tailored for community chronic diseases, leveraging advanced big data analytics. The system includes a meticulously designed chronic disease health record management framework, optimized for efficient ETL (Extract, Transform, Load) processes of medical data. This approach aims to minimize indexing overhead, enhance query execution speed and search capabilities, and maximize the use of aggregated computing resources. The system can be decomposed into four modules: ELT, data block creation, index creation, and querying. As an intermediate layer between users and distributed data management systems, this system can provide data upload, query execution mechanisms, and provide indexes to facilitate data search operations. The experimental results show that when the simulation step size is 50t, the maximum amount of data can reach 10 × 104. This method has a much higher retrieval efficiency than heuristic algorithms when processing massive data, further verifying the effectiveness and practicality of the chronic disease health record management system.
Deformation Monitoring and Analysis of Deep Foundation Pit Construction Period based on Internet of Things Technology
Authors: Xu Yunbo , Dai Xiaoning , Zhang Haojie , Ma Zhanming
Published: February 2025

In order to solve the problem of low detection accuracy in building structure safety monitoring, the author proposes a deformation monitoring and analysis during deep foundation pit construction based on Internet of Things technology. This method takes a large-scale construction project in a certain city as an example, applies neural network prediction models to deformation monitoring of foundation pits and main structures, and compares and analyzes the predicted results with actual measurement data. The experimental results show that the average MAE value of the predicted values is 0.15mm, and the average RMSE value is 0.17mm. The prediction accuracy of the neural network prediction model is high, which meets the accuracy requirements of deformation monitoring prediction. The use of Internet of Things technology can effectively ensure the safety of large buildings during construction, and has wider application value and prospects in deformation monitoring of future construction projects.
The Environment Perception and Path Planning Algorithm for Driverless Cars based on Computer Processing and Multi-sensor Fusion
Authors: Zhao Youjin
Published: February 2025

This paper selects suitable sensors and equipment based on the characteristics of urban road traffic. Then, a multi-sensor information fusion system based on millimeter-wave radar/camera is established. In this way, the road traffic safety can be effectively controlled. Then, by improving D-S evidential reasoning, a "goal-decision" two-level information fusion method is established. Then, the multi-layer fusion experiment of multi-source sensing data under a tunnel environment is carried out. Experiments show that the ROI region correlation using camera and millimeter wave radar can improve the detection accuracy by 9.66%, effectively solving the limitations of single-sensor detection for automatic driving under complex conditions. The D-S evidential reasoning method processes the automatic driving sensor data. This reduces the false report rate of the sensor by 2.75%.
Uses and protein content of green guaje seeds (Leucaena leucocephala (Lam.) de Wit offered in the markets of Southern Puebla State, Mexico
Authors: Reyes-Matamoros Jenaro , Martínez-Moreno David , López-Morales Dolores
Published: February 2025

Leucaena leucocephala, commonly known as guaje, is a woody plant endemic to Mexico with edible seed pods. Despite its historical significance as a resource for Mesoamerican peoples, the nutritional value of guaje remains poorly documented. This study aims to explore the uses and protein content of green guaje seeds offered in markets in Southern Puebla State, Mexico. The research involved interviewing vendors at various markets in Southern Puebla, including Tepeaca tianguis, Revolución market, La Rotonda market, and El Moralillo tianguis, where a total of 127 stalls were surveyed. Information was gathered regarding the source, uses, and preparation of guaje seeds. Additionally, the protein content of the seeds was analyzed to determine its nutritional value. Green guaje seeds were available at diverse sales points, with distinct vendor profiles: regatoneros (local resellers) predominantly at the Revolución and La Rotonda markets, while self-producing vendors were more common at Tepeaca tianguis. Eleven culinary preparations featuring guaje were identified, with guaxmole being the most prevalent (40.66%) and various chili sauces with guaje following (38.52%). Although most vendors were unaware of the medicinal uses of guaje seeds, a few recognized their traditional applications, including as a dewormer and for alleviating coughs, stomach pains, and cramps. The protein content in guaje seeds varied significantly, ranging from 6.991 µg/µl in seeds from San Pablo Zoyatitlanapan at the Revolución market to 22.3766 µg/µl in seeds from Acatzingo at the Tepeaca tianguis. This study highlights the underutilized potential of guaje seeds and provides valuable information on their protein content and culinary uses. The significant variability in protein content based on the seed's origin underscores the need for further research into factors affecting nutritional quality. Additionally, increased awareness of guaje's medicinal properties could enhance its utilization and benefits in local communities.
Population structure and spatial patterns of trees in successional stages of tropical forest in Gia Lai, Vietnam
Authors: Nguyen Minh Canh , Bui Manh Hung , Bernard Dell , Le Van Cuong , Nguyen Thi Bich Phuong , Nguyen Quoc Luan , Sven Wagner
Published: February 2025

Regeneration will determine the success of forest restoration and affect the sustainability of future forest ecosystems. Research has been conducted to evaluate the characteristics of the regeneration storey and their spatial distribution on the ground. The study has established 10 plots (100 m x 100 m) for secondary forests, 10 plots for old-growth forests. Sub-plots (2 m x 2 m) were set up systemically to investigate the regeneration. The results showed that 148 species in secondary forest and 130 species in old-growth forest were found. The number of families in the secondary forest was lower than in the old-growth forest by 3 families. The Simpson index of both forest states was high (0.9769 and 0.9799 respectively). Canonical correspondence analysis exposed that species composition of both species and families between the two types of stages was significant dissimilar. There were clear groups of species and families appeared together with similar frequency in plots proved by hierarchical classification. In both stages, the height frequency distribution was inverse-J shape forms. And these distributions were different in studied types. The good regeneration in two studies states of forests were 67.9% and 55.7%. Regeneration quality was significant associated with height and light classes. The number of regenerating trees generated in each 1-hectare plot of the secondary forest was almost twice that of the old-growth forest. In the secondary forest, most plots illustrated that the spatial pattern was random at all scales. Contrary, in the old-growth forest, the patterns were much more complicated.
Assessment of Air Quality of Karachi on Real-Time Rainfall Data through GIS Analysis
Authors: Kausar Dr. Anila , Khan Dr. Owais Iqbal , Ejaz Ms. Fizza , Lahori Dr. Altaf Hussain , Ambreen Dr. Romana , Hassan Dr. Mehdi
Published: February 2025

Karachi is a metropolitan city lying on the coastline of the Arabian Sea facing the effects of climate change. Weather patterns are changing and in a transition stage as the world is facing weather variability issues, due to climate change. The existing study was performed based on the real-time rainfall in Karachi held on January 29, 30, February 2, 3, and 4th, 2024. January and February are the month of winter in Pakistan and, in the winter, such continuous rainfall spells have never been witnessed by Karachiites for a long time specifically in February rainfall has never been witnessed on such a large scale. Due to such a long dry and cold season, Karachiites used to face health problems related to Air Quality in winter. Such heavy rain changes the environmental conditions in the winter consequently people feel fresh due to clean air.    Pollutants i.e., AQI, PM2.5, and SO2 have been monitored on selected days of 36 locations in Karachi. Interpolation techniques have been used in mapping. Results revealed that before the rain, in the air, all observed pollutants existed in large quantities i.e., AQI, PM2.5, and, SO2 ranged from 158.1-310.5, 70.1-260.5 µg/m³, and 113.5-246.9 ppbV respectively declines dramatically i.e., 69.05- 111.9, 48.3-136.8 5 µg/m³, and 50.04-99.9 ppbV after the rain. Results are analyzed through GIS analysis and further tested through Anova statistical analysis. Tree plantation and enhancing green cover can somehow reduce the contamination level of air. Therefore, instead of waiting for rain which does not usually happen in winter. Karachiites should participate in tree plantation activities/green infrastructure to clean the environment and reduce of health issues of Karachiites.
What Do Gases in the Large Intestine Have to Do with Health?
Authors: Pawełek Klaudia , Marta Patrycja Kinga , Huzarski Filip Maciej , Ferfecka Gabriela Monika , Rosa-Bończak Magdalena , Ossolińska Agata , Kłosowicz Weronika , Carlton Oliver , Stolarska Lucyna , Morawiecka Natalia
Published: February 2025

A healthy human gastrointestinal tract contains approximately 200 ml of gas, with an average daily elimination of 600 ml. Sources of intestinal gases include swallowing air and products of intestinal fermentation, primarily in the large intestine. The gases consist of nitrogen, oxygen, carbon dioxide, hydrogen, and methane, with carbon dioxide and hydrogen being the most abundant. The gut-brain axis, regulated by the nervous system and gut microbiota, influences intestinal motility, hormone secretion, and metabolic processes. Gut microorganisms produce short-chain fatty acids (SCFAs), which play a significant role in regulating energy homeostasis and enteroendocrine hormone secretion.
Disruptions in gut microbiota, such as in irritable bowel syndrome (IBS) and small intestinal bacterial overgrowth (SIBO), lead to changes in gas production, discomfort, and gastrointestinal symptoms. Diagnosis of these conditions relies on breath tests and ruling out other pathologies. Additionally, carbohydrate intolerances, such as fructose or lactose intolerance, result in excessive gas production and malabsorption issues. Celiac disease, an autoimmune condition, causes damage to intestinal villi, impairing digestion and absorption. A comprehensive approach to diagnosing and treating these conditions, including dietary modifications and microbiological interventions, plays a crucial role in improving patients' quality of life.
Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD) - current state of knowledge and perspective for further research
Authors: Bochenek Hubert , Bielicka Anna , Bzoma Michał , Gugulska Julia , Czerepak Irmina , Kapij Marcin , Niewczas Karolina , Brzozowska Adrianna
Published: February 2025

Introduction and purpose: aa Chronic coronary artery disease (CAD) is a prevalent condition affecting millions of people worldwide, significantly reducing quality of life and increasing the risk of myocardial infarction (MI). Percutaneous coronary intervention (PCI), often combined with stent implantation, is a cornerstone of CAD treatment. However, it induces a prothrombotic state, necessitating dual antiplatelet therapy (DAPT) to mitigate the risk of thrombosis and MI. Despite its established role, the optimal duration and specific composition of DAPT still remain under investigation. This article aims to summarise current knowledge on DAPT and highlight gaps requiring further research.
Description of the state of knowledge: DAPT typically involves acetylsalicylic acid (ASA) 75 mg and clopidogrel 75 mg for 6 months after PCI. While this is effective in reducing thrombotic events, it also increases bleeding risk. Current European Society of Cardiology (ESC) guidelines recommend tailoring DAPT duration and composition based on individual patient risk factors for bleeding and ischemia. Alternatives include shortening DAPT to 1–3 months for patients with high bleeding risk or intensifying it with stronger antiplatelet agents like ticagrelor or prasugrel for those at high ischemic risk. However, evidence supporting these alternatives remains limited, and require further investigation. Emerging options, such as vorapaxar, present additional potential, but also require further validation.
Summary: CAD management through PCI relies heavily on effective DAPT. Current strategies emphasize balancing ischemic and bleeding risks in optimising treatment. Although significant progress has been made, optimal DAPT regimens for specific patient groups remain uncertain, particularly in cases of shortened or intensified therapy. Continued research is crucial to refine treatment protocols and improve patient outcomes.
The Role of Gut Microbiota in Hypertension Management - A Review
Authors: Kot Alicja , Wojtczak Marta , Myśliwiec Natalia , Różycki Adrian , Pniak Michał , Miklis Paweł , Mawlichanów Maciej , Ciesielska Aleksandra , Sieradzka Aleksandra , Szerej Krzysztof
Published: February 2025

Introduction and purpose: Hypertension, or high blood pressure, is a condition characterized by persistently elevatedarterial pressure, leading to severe complications such as heart disease, stroke, and kidneyfailure. According to the World Health Organization (WHO), hypertension affectsapproximately 1.13 billion people worldwide, contributing significantly to global morbidityand mortality. Emerging research has revealed a significant connection between gutmicrobiota—the diverse community of microorganisms residing in the gastrointestinaltract—and the regulation of blood pressure. This comprehensive review explores the intricaterelationship between gut microbiota and hypertension, delving into the underlyingmechanisms, evidence from animal and human studies, and potential therapeuticinterventions.The state of knowledge: Key mechanisms involved into regulation of blood pressure include the production of short-chain fatty acids (SCFAs), modulation of the renin-angiotensin system (RAS), immune system regulation, and metabolite production such as trimethylamine-N-oxide (TMAO). Animal studies using fecal microbiota transplantation (FMT) have provided strong evidencefor a causal role of gut microbiota in blood pressure regulation. Human studies have shownassociations between gut microbiota composition and hypertension, highlighting the potentialfor dietary interventions, probiotics, prebiotics, physical activity and FMT as therapeuticstrategies.Summary: This review underscores the promise of microbiota-targeted therapies in managinghypertension and calls for further research to elucidate precise mechanisms and developpersonalized medicine approaches. Understanding the complex interactions between gutmicrobiota and hypertension could pave the way for innovative treatments and improvedcardiovascular health outcomes.
The role of diet and physical activity in PCOS - A Quick Review
Authors: Pawelec Natalia , Mazur Weronika , Hawajski Artur , Jankowska Natalia , Świerzyńska Adrianna , Kapciak Alicja , Górny Julia , Naja Katarzyna
Published: February 2025

Introduction: Polycystic Ovary Syndrome (PCOS) is a condition commonly found in young women. It is associated with many possible health consequences, ranging from acne, hirsutism, and obesity to fertility problems and even the development of endometrial cancer. Treatment is tailored to the individual, depending on various complications and needs. However, it is important to note that in most cases, the first recommended step is lifestyle modification. Key components of this include a healthy diet and physical activity. These recommendations are often overlooked or undervalued, with patients frequently expecting immediate pharmacological treatment and not believing in the potential effects of lifestyle changes.
Aim of Study: The purpose of this review is to explore and emphasize the crucial role of diet and physical activity in the management of women with PCOS.
Material and methods: PubMed and Google Scholar databases were used for the research.
Results and Conclusions: A well-balanced diet and regular physical activity play a crucial role in both the prevention and management of women with PCOS. While there are no specific diets or forms of physical activity recommended, research shows that any modifications towards eliminating unhealthy diet habits and sedentary lifestyles can significantly impact the quality of life for these women.
The impact of creatine supplementation on the development of kidney disease – literature review
Authors: Matczak Mateusz , Jasiński Karol , Broda Aleksandra , Hoksa Kacper , Jodłowski Krzysztof , Dubniewicz Ewa , Majewska Paula , Staszek Alicja , Łoskot Wiktoria , Szwech Jan
Published: February 2025

Introduction: Creatine, a widely studied dietary supplement, is known for enhancing athletic performance and muscle strength. Concerns persist regarding its impact on kidney health, as it raises serum creatinine levels, potentially confounding renal function assessments. This review examines creatine’s role in sports and clinical contexts, emphasizing safety and kidney health implications.
Aim of the study: To assess the effects of creatine supplementation on kidney function by summarizing evidence from case studies, clinical trials, and long-term research, addressing safety concerns in healthy and at-risk individuals.
State of knowledge: Research supports creatine’s efficacy in improving athletic performance, recovery, and muscle strength, with therapeutic benefits in neurodegenerative diseases, type 2 diabetes, aging, and chronic conditions. Robust trials show no adverse renal effects in healthy individuals, even with long-term or high-dose use. However, case reports highlight potential risks for individuals with pre-existing kidney conditions, especially without monitoring. Elevated serum creatinine levels caused by creatine can mislead eGFR-based renal function tests, warranting cautious interpretation.
Conclusions: When used as recommended, creatine is safe and effective for improving athletic and clinical outcomes in healthy individuals. While no direct renal impairment has been observed, caution is essential for those with kidney conditions. Pre-supplementation renal assessments, individualized dosing, and regular monitoring are advised to minimize risks. Creatine remains a valuable supplement, and further research is needed to confirm its long-term safety across various populations.
Review Of The Application Of Artificial Intelligence (AI) Exercise Training In Improving Cognitive Function In The Elderly Population
Authors: Zhang Tingran , Zhang Mufan , Luo Jiong
Published: February 2025

With the increasing cognitive dysfunction of the elderly and the incidence rate of dementia caused by aging, in recent years, many countries have studied and applied artificial intelligence (AI) to reduce the pressure on caregivers and improve the quality of life of dementia patients. This study comprehensively summarizes the impact of AI cognitive training on the mental symptoms of dementia patients from 2010 to 2024 through literature review. The results show that AI training has been used in multiple fields, breaking through many limitations of traditional action recognition technology. Through virtual cyberspace, real-time interaction of multiple senses can be achieved, allowing people to feel reality in the virtual network and accurately capture participants' actions; Through AI games, elderly people can improve their physical and cognitive functions, reduce depression and anxiety, meet the psychological and social needs of dementia patients, enhance their independence and dignity in life, and make objective assessments of cognitive function, which may help prevent dementia.
Gut Microbiota and Its Impact on Brain Function and Mental Health
Authors: Wójcik Zofia Martyna , Kamińska-Omasta Katarzyna , Omasta Bartosz , Krupa Olga , Pietrukaniec Paulina Dorota , Romańczuk Kuba Borys , Furtak Kinga , Stolarczyk Szymon Przemysław , Czerska Magdalena Agata , Rybak Daria
Published: February 2025

The intestinal microbiota is a complex ecosystem playing a crucial role in maintaining human homeostasis. It consists of billions of microorganisms, including bacteria, viruses, fungi, and archaea, which closely interact with their host. Recent research reveals that microbiota not only supports metabolic and immune functions but also influences central nervous system (CNS) regulation via the gut-brain axis, a two-way communication system.
The gut-brain axis modulates neurotransmitter production (e.g., serotonin, GABA), immune responses, and interacts through bacterial metabolites. Dysbiosis, or microbiota imbalance, is linked to neuropsychiatric disorders like depression, anxiety, and autism. Maintaining microbiota balance is essential for mental health.
This paper reviews literature on the impact of gut microbiota on mental health, focusing on gut-brain axis mechanisms, diet, and therapeutic potential. These findings are especially relevant for personalized medicine approaches targeting microbiota to manage mental disorders.
CLOVES Syndrome: A Review of Clinical, Genetic, and Therapeutic Aspects
Authors: Podolec Julianna , Ciraolo Silvia , Wojda Joanna , Sobiński Adam , Kościuszko Zuzanna , Kurza Katarzyna , Agnieszka Kulczycka-Rowicka  , Czerwonka Matylda , Lesiczka-Fedoryj Katarzyna , Walczak Anna
Published: February 2025

Purpose of Research: The research aims to provide an in-depth understanding of CLOVES syndrome, detailing its clinical features, epidemiology, etiology, and diagnostic criteria. It focuses on the role of PIK3CA gene mutations, challenges in diagnosis, and treatment options, including PI3K/AKT/mTOR pathway inhibitors.
Research Materials and Methods: This article is based on a review of the current literature and clinical reports from various sources. The methodology includes a collection and synthesis of clinical data, imaging findings, and genetic analyses from published case studies and medical literature. The primary materials used in the research include: clinical case reports and studies, imaging studies, genetic analysis, therapeutic interventions, epidemiological data, literature review and data analysis.
Basic Results: CLOVES syndrome affects fewer than 200 individuals worldwide, with symptoms appearing at birth or early childhood. It can lead to serious complications such as nerve compression, deep vein thrombosis, and pulmonary embolism. Diagnosis involves genetic testing and imaging, and sirolimus shows potential in managing symptoms.
Conclusions: CLOVES syndrome is a rare, non-hereditary overgrowth disorder caused by a PIK3CA gene mutation. Early diagnosis and a multidisciplinary approach are vital for managing this complex condition and improving patient outcomes.
Noticias íntimas y sentimientos en los discursos de la vida: el legado de los tribunales inquisitoriales de Cartagena, México y Lima
Authors: Silva Prada Natalia
Published: February 2025

Este capítulo está dedicado a explorar las posibilidades que para el estudio de la vida íntima de personajes anónimos de la historia brinda una parte muy peculiar de los procesos inquisitoriales llamada discurso de vida. Esos procesos son nuestra fuente documental primordial y el discurso de vida una parte de la fuente que se convierte en elemento esencial del método para descifrar la vida íntima de seres sin aparente importancia. De los documentos que una vez formaron parte de los tribunales inquisitoriales de Cartagena, México y Lima, recupero cuatro vidas de hombres y mujeres que vivieron entre el Mediterráneo y el Atlántico. El corpus documental básico procede de los acervos del Archivo Histórico Nacional de España, Fondo Inquisición, alojado en el
Portal de Archivos Españoles (pares), y la Biblioteca Digital Mexicana, así como algunas fuentes primarias editadas, antiguas y contemporáneas.
Correos particulares e íntimos dentro de un monopolio postal: acceso al correo en el Virreinato de la Nueva Granada (1750-1780)
Authors: González Martínez Nelson Fernando
Published: February 2025

El objetivo de este capítulo es analizar las posibilidades que ofreció el aparato de correos neogranadino para movilizar correspondencia no oficial. A pesar de la reorganización y regulación que propusieron los Borbones durante el siglo xviii, varios sectores particulares3 poseyeron la capacidad de enviar y recibir correspondencia. De hecho, gracias a los múltiples servicios de movilización postal pudieron circular percepciones, opiniones y contenidos que podríamos considerar íntimos. A diferentes escalas, fue posible intercambiar correspondencia que no tenía un emisario o receptor gubernamental. Hombres y mujeres residentes en el Nuevo Reino de Granada (alfabetos y analfabetos) pusieron en circulación correo que expresaba emociones, percepciones e intereses que hacían parte de una esfera no necesariamente gubernamental. Propongo reflexionar sobre el ambiente comunicativo que ofrecía el correo neogranadino para movilizar correos que estaban relacionados con un ámbito particular e íntimo. Más que los contenidos, me interesa examinar las circunstancias y expectativas
que permitieron el uso de los servicios postales para movilizar correspondencia relacionada con ámbitos no públicos. Evidentemente, la estatalización del correo por parte de los Borbones propuso nuevas reglas y pautas para el intercambio de correspondencia que indudablemente repercutió en las logísticas de comunicación dentro del territorio neogranadino.
Heterogeneidad del discurso en un relato amazónico: el caso de la “Historia de Dijoma”, de Ángel Kuyoteka Fijikomui
Authors: Zuluaga Hoyos Gustavo Adolfo
Published: February 2025

El capítulo se divide en tres secciones. En la primera, se examinan los conceptos de heterogeneidad y de sujeto de la enunciación a la luz de la variante del Dijoma jágai confeccionada por Kuyoteka Fijikomui. En la segunda, se hace un recuento pormenorizado de esta variante, a fin de subrayar sus rasgos específicos en relación con otras variantes de esta misma historia amazónica.
Y, finalmente, en la tercera sección, se examinan algunos pasajes específicos en los que se pueden advertir manifestaciones de una enunciación marcada por la heterogeneidad, esto es, por el entrecruzamiento de múltiples horizontes discursivos.
Beyond The Status Quo
Authors: Manley Felix
Published: February 2025

How can expert service and delivery raise the bar for 3D printing bureaux and set them apart from their competitors?
Advantages of the single-center model in domino transplant processes: Operational planning and management experience
Authors: Huseynov Amil , Kuşlu Çicek Sevim Nuran , Tuncer Murat
Published: February 2025

BACKGROUND

Kidney transplantation is one of the most effective treatments for patients with end-stage renal disease. However, many regions face low deceased donor rates and limited ABO-compatible transplant availability, which increases reliance on living donors. These regional challenges necessitate the implementation of kidney paired donation (KPD) programs to overcome incompatibilities such as ABO mismatch or positive cross-matching, even when suitable and willing donors are available.

AIM

To evaluate the effectiveness of a single-center domino KPD model in both operational planning and clinical management processes and to assess its impact on clinical outcomes.

METHODS

Between April 2020 and January 2024, we retrospectively evaluated patients enrolled in our center’s domino kidney transplantation program. Donor-recipient pairs unable to proceed due to ABO incompatibility or positive cross-matching with their own living donors were included. Donors and recipients were assessed based on blood group compatibility, HLA tissue typing, and negative cross-match results. A specialized computer algorithm grouped patients into three-way, four-way, and five-way chains. All surgical procedures were performed on the same day at a single center.

RESULTS

A total of 169 kidney transplants were performed, forming 52 domino chains. These domino KPD transplants accounted for a notable proportion of our center’s overall transplant activity, which included both living donor kidney transplants and deceased donor transplants. Among these chains, the primary reasons for participation were ABO incompatibility (74%), positive cross-matching (10%), and the desire to improve HLA mismatch (16%). Improved HLA mismatch profiles and high graft survival (96% at 1 year, 92% at 3 years) and patient survival (98% at 1 year, 94% at 3 years) rates were observed, as well as low acute rejection episodes.

CONCLUSION

The single-center domino KPD model enhanced transplant opportunities for incompatible donor-recipient pairs while maintaining excellent clinical outcomes. By providing a framework that addresses regional challenges, improves operational efficiency, and optimizes clinical management, this model offers actionable insights to reduce waiting lists and improve patient outcomes.
Territories of mourning: Addressing submerged problems of grief through multidisciplinary care
Authors: Marano Giuseppe , Mazza Marianna
Published: February 2025

Mourning and grief are natural responses to loss and can be especially complex and prolonged in the context of end-of-life care. Caregivers play a crucial role in supporting individuals through this difficult journey, often balancing their own grief with the need to provide care. This paper explores the experiences of mourning and grief in hospice settings, with a focus on the emotional challenges faced by both patients and caregivers during the grieving process. Psychological support plays a crucial role at the end of life in a multidisciplinary care approach. By addressing the complex interplay between biological disease and psychological well-being, healthcare professionals can provide more comprehensive and compassionate care. A deep understanding of mourning and elaboration of grief would improve the implementation of suitable support interventions and facilitate collaboration among family members and healthcare teams, ultimately improving the quality of end-of-life care and promoting the well-being of both patients and their families.
DIABETIC MIDFOOT CHARCOT: WHEN TO OPERATE, A STAGED APPROACH TO DECISION MAKING
Authors: Tiruveedhula Madhu
Published: February 2025

Introduction

Diabetic midfoot Charcot neuroarthropathy (CN) is a progressive condition which presents as a hot swollen foot to a rocker bottom deformity with ulcer and resultant osteomyelitis. Literature report of a subjective indications for surgery generally after a failed prolonged immobilization in a total contact cast. The aim of this study is to define objective indications of progression of midfoot CN and interventions at each stage of the disease.

Patients and Methods

Notes and radiographs of consecutive patients presented to Basildon Diabetic foot unit since 2018 with midfoot CN were reviewed. Inclusion criteria were all patients with midfoot CN and were followed for a minimum 12 months with radiographs. Exclusion criteria were patients lost to follow before 12 months or where inadequate radiographs were available. Patients with ankle/ subtalar Charcot were excluded.

Results

A total of 182 patients with midfoot CN were seen since 2018, of these 88 patients underwent surgical reconstruction. 3 radiographs features: lateral Mearys angle, calcaneal pitch and cuboid height were noted to be diagnostic for diagnosis and monitoring of the progression of the midfoot CN. 5 stages of disease were described (Basildon classification) with stage 1 and 2 were managed with percutaneous tendo-Achilles lengthening (TAL). Progression of above radiological parameters is an indication for surgical stabilisation. Lateral column involvement is indicated by the drop in cuboid height which rapidly progresses to ulcer formation.

Conclusion

Motor neuropathy induced stiff and contracted muscles results in progressive midfoot CN. The radiological markers described are shown to be reliable and reproducible indices for the progression of the disease process. In-clinic procedures such as TAL has shown to slow or revert the earlier stages of disease, however worsening of these markers are reliable guide for indication for surgical stabilisation.”
CUSTOM 3D-PRINTED IMPLANTS FOR CRITICAL-SIZED BONE DEFECTS IN FOOT AND ANKLE SURGERY: A MULTICENTRE COLLABORATIVE STUDY
Authors: Mangwani Jitendra , See Abbas , Houchen-Wolloff Linzy
Published: February 2025

Introduction

The treatment of critical-sized bone defects in foot and ankle surgery remains challenging. Traditional methods, such as bone transport, bulk allograft, vascularized bone graft, and Masquelet procedures carry risks including multiple surgeries, donor site morbidity, infection, and non-union. Recently, custom 3D-printed implants have emerged, offering improved anatomical compatibility, eliminating the need for tissue harvesting, and often requiring only a single operation. This study aims to present the largest UK series of custom 3D-printed implants in foot and ankle surgery.

Methods

A retrospective multicentre collaborative study was conducted in 10 NHS Trusts. Demographic, surgical and radiographic variables were recorded including: age; sex; side; type of operation; complications; and postop imaging at 6 weeks, 3 months, 6 months and 12 months. Baseline characteristics were described for demographic variables. Categorical variables were expressed as frequencies and percentages.

Results

Data was collected on a total of 34 patients. The mean age of patients was 54 years (range 29 to 83). 68% of patients were men. Avascular necrosis was the most common indication for surgery (35%) followed by trauma (21%), total ankle replacement failure (21%), infection (12%), Charcot arthropathy (6%) and AVN and infection (3%). The most common operation performed was a fusion augmented with a truss (44%) and 91% of patients had a combination of regional and general anaesthetic. All patients had an ASA grade of less than 4. Of the patients that had follow-up imaging, the implants were reported intact by 94% at 6 weeks, 78% at 3 months, 68% at 6 months and 67% at 12 months.

Discussion

This is the largest case series of custom-made foot and ankle implants in the UK to date. The clinical and radiographic outcomes at one year Follow-up are satisfactory. Further work is required to assess long term implant survivorship.
A TEN-YEAR FOLLOW-UP OF ARTHROEREISIS SCREWS IN ADULT FLAT FOOT RECONSTRUCTION
Authors: Bhamra Jagmeet , Fell Adam , Hashem Mohamed , Clark Callum
Published: February 2025

Introduction

The use of an arthroereisis screw is well described in the paediatric population for the correction of flexible flat feet. There are no long-term studies of its use in adults. We performed a functional and radiographic evaluation of a single centre, single surgeon series following the use of a subtalar arthroereisis screw, to augment reconstruction in adult patients with acquired adult flat foot deformity secondary to spring ligament / tibialis posterior tendon failure.

Methods

We performed a retrospective review of 40 consecutive feet with stage 2 PTTI that underwent flexor digitorum longus transfer, reefing of the spring ligament, translational medialising calcanaeal osteotomy and augmentation with an arthroereisis screw (Kalix, Integra; 22 feet or ProStop, Arthrex; 3 feet), between 2005 and 2021. All arthroereisis screws were electively removed at 6 months. Radiographic values were assessed pre- and post-operatively at 1-year with functional results both at 1-year and average 10-year follow-up.

Results

The mean age of patients at surgery was 60 years (range 44–77 years). There was a significant improvement p<0.05) in radiographic parameters (calcaneal pitch, Mearys angle, medial column height, talus to 1st and 2nd metatarsal angle and talonavicular coverage). There were no re-operations. Manchester Oxford Foot Questionnaire, EQ-5D and VAS scores at an average of 10.6 years for pain were reported as 2.3 (range 0–64, Likert scale), 0.94 (range -0.59–1) and 0.2 (0–10), respectively. Health TODAY averaged at 91.4%.

Conclusion

We conclude that the use of an arthroereisis screw is a promising adjunct to conventional reconstruction in adult PTTI that protects the spring ligament repair and tendon transfer during the initial healing time of the soft tissues. Excellent radiological and functional results were obtained in our cohort with high levels of patient satisfaction at long-term follow-up.
Multimodal approach in the diagnosis and management of Eales disease: a case report
Authors: Adriono Gitalisa Andayani , Mahfudz Sausan Rasyid , Triyoga Ichsan Fauzi
Published: February 2025

Eales disease is a rare idiopathic occlusive retinal vasculitis with low prevalence in the general population. Its infrequent occurrence limits diagnostic and treatment guidelines, emphasizing the need for ongoing reports to establish effective protocols. This case report describes a patient presenting with symptoms of bilateral retinal vasculitis. Fundus examination revealed vitreous hemorrhage (VH) and peripheral retinal vasculitis. Laboratory and imaging tests were performed to exclude differential diagnoses, leading to Eales disease as the primary diagnosis. Pars plana vitrectomy, panretinal laser photocoagulation, intravitreal anti-vascular endothelial growth factor, and anti-tuberculosis therapy were administered. Long-term follow-up showed satisfactory outcomes. This report suggested Eales disease to be a diagnosis of consideration for ophthalmologists encountering male patients with recurrent VH. Clinical suspicion, including appropriate laboratory testing and imaging, is essential to developing a holistic approach to diagnosis and management, aiming to prevent progression and achieve optimal visual outcomes.
Radiological and histological assessment of a novel interlocking three-dimensional miniplate for mandibular angle fractures: an animal study
Authors: Kreshanti Prasetyanugraheni , Noviana Deni , Priosoeryanto Bambang Pontjo , Kekalih Aria , Rahyussalim  , Supriadi Sugeng , Hatibie Mendy Juniaty , Sukasah Chaula Luthfia
Published: February 2025

BACKGROUND Open reduction and internal fixation are considered the gold standard for managing mandibular fractures, as they effectively restore anatomical structure and functionality. Three-dimensional (3D) miniplates were developed to obtain a geometrically stable structure. However, the rigid structure of 3D miniplate may cause screw holes to be located within the fracture lines or directly above important anatomical structures. Hence, we have developed customizable interlocking 3D miniplates that allow for modifications in the configuration of the horizontal miniplates and vertical cross-struts to meet specific requirements.
METHODS This study included 24 goats divided into 2 groups: interlocking 3D miniplate and standard plate. Each group was further divided into subgroups sacrificed on Days 5, 28, and 56. Radiological assessments were performed to evaluate bone, muscle, peri-implant bone, and peri-implant muscle density. Histological assessments were performed using Masson's trichome (MT) for bone healing evaluation and hematoxylin and eosin (H&E) staining for biocompatibility.
RESULTS Radiological assessment indicated an increase in density across all measured parameters from Day 5 to 56. Histological evaluation from MT staining showed a significantly higher fibrocartilage in the interlocking 3D miniplate group (6.109%, IQR 1.453–10.828) compared to standard plate (1.311%, IQR 0.636–2.553; p = 0.001). Furthermore, H&E staining showed significantly higher inflammatory cell counts in the standard group on Days 28 and 56 compared to the interlocking 3D miniplate group (p = 0.027).
CONCLUSIONS This study concluded that the interlocking 3D miniplate showed better bone healing properties and biocompatibility than the standard plate.