bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Microplastics in the Environment on Human Health and Its Policy Analysis: A Case Study on China
Authors: Zhou Yixin , Guo Zhengye , Woo Victoria Xiangyi , Cheng Zefan , YU IVAN
Published: February 2025

Microplastics, as a new type of pollutant, have received extensive attention from scholars in recent years. This paper explores the impact of microplastics on human health from the interdisciplinary perspective of health economics and public policy in China. The paper finds that plastic wastes are influencing factors of the increasing demand for respiratory medicines, probably owing to the release of airborne microplastics. Additionally, this paper focuses on the development of microplastics policy in China and other countries, drawing on the experience of microplastics pollution control worldwide. The paper puts forward recommendations in the following four aspects: 1.Introduce targeted policies and increase monitoring of microplastics. 2.Clarify the responsibilities of each department and promote cross-sectoral collaboration. 3.Strengthen international exchanges and establish multi-platform cooperation. 4.Enhance the dissemination of knowledge about microplastics and raise citizens’ environmental awareness in China.
The Impact of Stigma on Adolescents with Major Depression Disorder (MDD) and Anxiety Disorders
Authors: Yang Muyi
Published: February 2025

Over the few decades, major depression disorder (MDD) and anxiety disorders in adolescents have become a concern. MDD, characterized by persistent sadness and loss of interest, and anxiety disorders, marked by excessive worry, are increasingly prevalent. Despite this, the stigma surrounding mental health often prevents adolescents from seeking the help they need. This literature review explores the relationship between stigma and MDD/anxiety disorders, examining how public misconceptions and societal attitudes exacerbate the issue. It also highlights the critical role of early diagnosis, timely intervention, and appropriate treatment. The review further discusses the importance of public education in combating stigma, the potential of online counseling services to address accessibility and affordability issues, and the role of school-based mental health services in offering support. By addressing these critical issues, this study aims to contribute to a paradigm shift in mental health awareness and care during this pivotal life stage.
Investigating HLA-E Peptide Binding on Natural Killer Cells for Targeting Breast Cancer Stem Cells
Authors: Zhang Shuman
Published: February 2025

-Breast cancer stem cells (BCSCs) are a major challenge for many conventional therapies such as chemotherapy and radiotherapy. Natural killer cells are often mentioned in immunotherapy, but the need for activation makes NK cell immunotherapy less than satisfactory. Recent studies have found that the MHC HLA-E protein has an abundant peptide expression that can activate NK cells. This study will focus on using HLA-E-expressed peptides in MHC proteins to activate NK cells and develop new possibilities for immunotherapy.
The Three-child Policy and Chinese Women: Career Development and Family Responsibility Choice under Patriarchal Culture
Authors: Liu Xinyu
Published: February 2025

The impact of China’s three-child policy on women’s career development and family responsibilities is explored in this article. Research findings indicate that in a society deeply rooted in patriarchal culture, Chinese women face workplace discrimination and reduced career opportunities due to childbirth while pursuing their professional development. By comparing the professional and family roles of women in regions with profound patriarchal influence and economically developed culturally open areas, the article reveals the impact of regional cultural differences on women’s career development. The research results show that women in economically developed areas have more opportunities and support for career development, whereas women in regions deeply influenced by Confucian culture are more constrained by traditional gender roles and family responsibilities. The novelty of this study is that it demonstrates that marital equality and family support significantly influence women’s career and family responsibilities, a factor that has been overlooked in previous research. Based on these findings, the article proposes a series of policy recommendations aimed at promoting gender equality and supporting women’s dual roles in both career and family life, providing empirical research foundations for government departments and academia.
Treating Psoriasis: Simple Introduction about Acitretin and Tacrolimus
Authors: Yang Aofei
Published: February 2025

Psoriasis is a skin infection disease that is related to dysfunction of the immune system. Plaque psoriasis is a common and typical psoriasis; it can be triggered by multiple factors, for example, environmental triggers and genetic factors. Skin with plaque psoriasis can be itchy and red, appear inflamed, and have scaly patches; the infected region can last for months and may leave permanent pigmentation. Keratinocytes (skin cells) are related to psoriasis; as homeostasis is disturbed, excess keratinocytes are produced, and surplus skin cells lead to psoriasis. Acitretin and tacrolimus are both drugs that can help with psoriasis but with different mechanisms.
An analysis of the influence of parents’ education level and work status on their children’s education level and work status
Authors: Cai Jianlin
Published: February 2025

The influence of parent’s education level and working conditions on their offspring is a long-lasting topic in the field of economics research. Academic circles have conducted extensive research on intergenerational mobility, but few studies systematically discuss the influence of parents’ education level and working conditions on their offspring. This paper mainly focuses on the relationship between the father’s education level, job level, whether he works in the system and whether he works in a foreign-funded enterprise and his offspring’s English ability, education background, management work, and income level, and makes an empirical analysis by using quantitative research methods. The research results of this paper have formed a positive and beneficial supplement to the research in the field of intergenerational mobility.
Artemisinin treats SNU-C2A cell line for colorectal cancer by inhibiting cell growth through undergoing ferroptosis.
Authors: Chi Yueh-Shan
Published: February 2025

Colorectal cancer is one of the major types of cancer that humans are suffering from; however, drugs that can be used for treatment with no side effects have still not been discovered. By research, Chinese traditional medicine called artemisinin (ART) was known for undergoing ferroptosis in cells. Therefore, some experimental tests need to verify the effect of whether artemisinin allows ferroptosis to apply to colorectal cancer cells. The result of this experiment can allow a better understanding of the direction of colorectal cancer treatment and how Chinese traditional medicine can perform as treatments for CRC. Therefore, during this experiment, ART was used to test ferroptosis in the SNU-C2A colorectal cell line to see whether it’s a suitable drug to use for CRC patients.
Meningitis caused by N. meningitidis: How to prevent this “younger generation killer”?
Authors: Xu Longchen
Published: February 2025

Neisseria meningitidis is a gram-negative bacterium that inhabits the mucosal surface of the nasopharynx in approximately 10% of healthy persons. It stands out as a leading etiology of meningitis, particularly among children, adolescents, and young adults. Meningococcal infections account for an estimated 1.2 million cases annually worldwide, with a death toll exceeding 135,000. These infections are most prevalent in the “meningitis belt” of sub-Saharan Africa and have historically occurred in cyclic patterns in China. Chemoprophylaxis using antibiotics like rifampicin, ciprofloxacin, and ceftriaxone is effective in eliminating bacterial carriage and preventing disease spread. Vaccination represents another crucial preventive measure. This review provides an overview of meningococcal meningitis, emphasizing the importance of early diagnosis, chemoprophylaxis with antibiotics like ceftriaxone, and vaccination as key strategies to combat this deadly disease, particularly among vulnerable populations like infants, adolescents, and young adults.
Exploring Internal Factors of Gender Disparity in STEM Courses and Majors: A Case Study of Hong Kong
Authors: Liu Yicen
Published: February 2025

STEM education plays a crucial role in developing innovative solutions to complex global challenges, yet women remain significantly underrepresented in these fields, particularly in colleges and universities. According to the National Center for Science and Engineering Statistics, while women comprise over 50% of college students, they represent only 20% in engineering and 19% in computer science of the STEM workforce, highlighting a significant gender gap in STEM courses and majors. (NCSES, 2023).This study examines the psychological and social mechanisms underlying female underrepresentation in STEM education in Hong Kong, specifically focusing on class and major enrollments. By reviewing academic literature and survey data, the study identifies three critical internal factors that contribute to this specific gender disparity: negative self-perceptions fostered by traditional gender stereotypes, diminished sense of belonging due to the underrepresentation of female role models, and reduced interest in STEM subjects stemming from internalized societal expectations. Through examining these interconnected psychological barriers, this study provides insights into how gender stereotypes are internalized and shape female students’ academic choices suggesting possible interventions to create a more inclusive STEM educational environment in Hong Kong.
A Study of Bioactive Antimicrobial Glass-Ceramics’ Composition, Synthesis, Mechanisms, and Biomedical Applications
Authors: Yao Shuhan
Published: February 2025

Bioactive and antimicrobial glass-ceramics have garnered significant interest due to their distinctive attributes, high bioactivity, supreme mechanical strength, and effective antibacterial characteristics. These materials provide extensive application potential in orthopedics and dentistry, mainly where infection control and tissue integration are paramount. The bioactivity of glass ceramics facilitates their integration with human tissues and concurrently suppresses microbial proliferation via processes including ion release, diminishing the likelihood of implant-associated infections. This study seeks to elucidate the creation and implementation of bioactive antimicrobial glass ceramics, emphasizing design concepts, synthesis techniques, antibacterial mechanisms, and biological features of these materials. Specifically, how enhancements in the manufacturing process influence the physical and chemical characteristics of the materials, consequently augmenting their antibacterial efficacy and biocompatibility. Furthermore, the prospective uses of these materials in the biomedical domain, such as their use in bone regeneration, dental implants, and healing wound dressings, will be examined, along with anticipated future development trajectories. As this research continues, bioactive antimicrobial glass-ceramics are anticipated to provide innovative choices for improving the medical safety and biological efficacy of medical implants, therefore improving biomaterial technology.
Evaluating the effects of the targeted poverty alleviation programs on development: The case of China
Authors: Li Xiaoyang
Published: February 2025

China eradicated absolute poverty recently. This research assessed the role of the targeted poverty alleviation program in fostering economic development in China. This study employed a difference-in-differences design and a propensity score matching estimation. It can be found that counties selected as targeted impoverished counties have significantly worse economic conditions than their counterparts. However, receiving policy treatment as targeted counties fosters economic development. There is little heterogeneity in the impact of the poverty alleviation program. Why the targeted poverty alleviation program has a significant role in eliminating absolute poverty in China will also be explained.
Analysis of Influencing Factors on Sleep Quality of College Students
Authors: Zhang Yaowen
Published: February 2025

Sleep quality is a critical aspect of human health, and it lays the foundation for all human activities. The quality of sleep not only affects the speed of thinking, and the rigor of calculation but also affects the activity of the body. This study is based on the factors that affect the sleep quality of college students globally, specifically by adding different physiological factors to psychological factors which contain the most common factors when researching students’ sleeping quality, for example, level of pressure. The physiological factors include geographical region, major, and so on. This study collected different experimental data globally to investigate whether geographical region and major have an impact on students’ sleep and what kind of impact it has. Results indicate notable differences in sleep quality, with medical students and those in certain geographic regions experiencing higher rates of sleep disturbances. The findings underscore the need for tailored support systems that consider academic pressures and regional contexts to improve student well-being.
Treatment of Pneumoniae: A Comparison of the Effects of Colistin and Ceftazidime-Avibactam
Authors: Liu Suchang
Published: February 2025

This study compares the cure rate, risk, and benefit-risk of two drugs used to treat pneumonia by surveying statistics from five U.S. hospitals. Data from the past few years show that bacterial pneumonia is a highly contagious and pathogenic disease that is spreading worldwide. A review of the data compiled from previous studies concluded that there are two main drugs used for the treatment of pneumonia and that the two drugs use different mechanisms in the treatment of pneumonia. One is a combination of antibiotics to which bacterial resistance has been found to develop, while the other has been shown to be potentially harmful to the human renal system and nervous system. Therefore, the selection of the appropriate drug in combination with the patient’s complex multispecies infection is an important future research direction.
A General Review of the antibiotics Mupirocin and Cefuroxime on Paronychia caused by S. Aureus and S. Pyogenes species
Authors: Yang Jiayi
Published: February 2025

This article will focus on the treatment of paronychia with cefuroxime and mupirocin, which are two different types of antibiotics frequently prescribed by medical professionals for the treatment of nail infections caused by common pathogenic bacterial species. Cefuroxime is an antibiotic isolated from a fungus and is characterized as a type of class II cephalosporin that belongs to the class of B-lactam antibiotics that binds to penicillin-binding-proteins in bacteria, therefore inhibiting bacterial peptidoglycan (cell wall) synthesis and kills the cell. Mupirocin (more commonly known as Bactroban) is another antibiotic that is isolated from a fellow bacteria species and works by obstructing bacterial aminoacyl-tRNA synthesis in various species of bacteria that may be susceptible to the mechanism. However, the application of these antibiotics onto infected regions does not guarantee a complete elimination of the pathogens due to the rise of antibiotic resistance genes throughout the bacterial population. A short discussion will follow all the presented materials, as well as the referenced materials.
Study on the Obstacles and Paths of the Outbound Output of Chinese Self-Media Platforms from a Cross-Cultural Perspective
Authors: Fu Yu
Published: February 2025

This paper explores the outbound output of Chinese self-media platforms from a cross-cultural perspective. In the context of globalization and convergence media, the issue of outbound output from Chinese self-media platforms has received widespread attention, but there are still insufficient path explorations in the related research. Although self-media has developed with strong momentum, it faces numerous challenges such as content regulation. A deep exploration of its outbound output strategies is of enormous significance for enhancing international communication power. This paper analyzes the low barriers to use and high openness of Chinese self-media platforms, as well as the obstacles faced in cross-cultural outbound output, such as implicit expression styles, the local characteristics of emotional expression leading to comprehension barriers for foreign audiences, technical issues with internet speed and interconnectivity, and cultural differences resulting in varying information reception tendencies and access channels among audiences. The paper concludes with the need to expand communication channels and collaborate with traditional media. On this basis, the following suggestions are made: efforts should be made to optimize outbound output paths and improve content to enhance the international influence of Chinese self-media platforms and promote effective cross-cultural understanding and exchange.
Generative AI Used by Social Influencers and Their Trust Among Generation Z
Authors: Tan Xinyan
Published: February 2025

Social influencers are people who emerge on social media platforms with considerable followers. In the era of artificial intelligence, there are social influencers tend to use generative AI to help them complete several tasks, for instance, data collection, data analysis, AI-generated music, images, text, videos etc. This paper will focus on the perspective of visual generative AI seen by audiences. The main purpose of the study is to investigate how generative AI used by social influencers would influence trust among Generation Z. In order to back up my research, the source credibility theory is applied. Questionnaires are handed out in the way of qualitative methods. This study explored the perception of different Generation Z for the trust for social influencers using generative AI.
How Perceived Sustainability-related Climate Influences Residents’ pro-environmental Behavior Intention in Tourism Destinations: An Integration of TPB and NAM
Authors: Huang Yaru
Published: February 2025

The environmental issues are vital to the development of tourism. Tourism destination residents take huge responsibility for environmental and problems and need to understand residents’ intention to get involved in pro-environmental behaviors. The research focuses on how perceived sustainability-related climate (PSRC) influences the intention of residents to engage in pro-environmental behavior behavior. After data is gathered from different countries via surveys, I used the structural equation model (SEM) to analyze it. Results indicate that PSRC positively influences the residents’ intention of pro-environment behavior, mediated by Perceived Behavioral Control, Subjective Norms, Attitude, and Personal Norms, Attribution of Responsibility and Awareness of Consequences. The outcome encourages residents’ pro-environmental behaviors.
The Role of Excipients and Nanoparticles in Improving Cancer Treatments: A Review
Authors: Idanawang Josephine
Published: February 2025

Nanoparticle-based drug delivery systems have emerged as an approach to combat the issues associated with conventional cancer treatments. These systems improve drug delivery by enhancing bioavailability, targeting cancer cells more effectively, and reducing side effects. Excipients, traditionally considered inactive ingredients, play a critical role in optimizing these systems by influencing drug absorption, pharmacokinetics, and therapeutic efficacy. This review will evaluate recent advancements in the use of excipients and nanoparticles in cancer treatment, with a focus on chitosan-based nanoparticles, tannic acid-paclitaxel nanoparticles (TAP NPs), and fully active pharmaceutical ingredient nanoparticles (FAPINs). Chitosan nanoparticles exhibit excellent safety profiles and efficient drug delivery, making them suitable as lipophilic anticancer drug carriers and targeting colon cancer cells. TAP NPs tackle challenges like poor drug solubility and toxicity, particularly in breast cancer treatment, and FAPINs combine treatment and imaging in one system, making it easier to target tumors. The strengths, limitations, and suggested future actions for these approaches are discussed to provide an understanding of their potential in cancer therapy.
Analysis on Current Situation of AdolescentConsumption
Authors: Cheng Ziang
Published: February 2025

Social media and advertising have had an important influence on the consumption attitudes of teenagers. The internet burgeons very fast; teenagers are able to be exposed to a lot of consumer information through various social apps, and many brands impact their shopping decisions through celebrity endorsements, recommendations from internet celebrities, and other means. Additionally, teenagers often use “following the trend” and “peer effect” as driving forces for consumption, hoping to gain social and identity recognition through consumption. Therefore, fashion trends, brand influence, and social circle influence often determine their consumption choices. To prevent the spread of this situation. This study investigates and analyzes the consumption status of teenagers in the form of questionnaires. The results show that many teenagers are influenced by the surrounding environment and the Internet. This study reminds teenagers to adhere to their initial consumption concept and not to be influenced by the Internet and the environment.
The Impact of Social Media on Teenagers —— Take TikTok as an Example
Authors: Liu Kai
Published: February 2025

In the era of mobile Internet, TikTok has become a mainstream platform for teenagers with its amazing development speed. This paper will examine the positive and negative effects of TikTok on teenagers. On the positive side, TikTok provides teens with a creative outlet for self-expression and identity formation, which could fulfil the psychological needs for achievement and social belonging described in Maslow’s ladder of needs. However, due to the addictive nature of the brain’s dopamine response to short and fast-paced content, TikTok has also brought serious drawbacks to teenagers. This addictive phenomenon, dubbed “TikTok brain,” can disrupt real-life activities, including studying and social interactions. In addition, the “Fear of Missing Out” (FOMO) caused by TikTok use is also fuelling anxiety among teenagers. By describing the duality of TikTok’s effects, this paper highlights the need to balance the use of TikTok with awareness of its psychological impact on teenagers.
Identifying the role of circRNAs in the interaction with miRNAs during the limb regeneration in axolotl
Authors: Liu Zuying
Published: February 2025

The current literature lacks a comprehensive assessment of circular RNA’s role in the limb regeneration in the axolotl model, which has become the foundation for recent investigations into this topic. This paper aims to address this important gap by presenting a detailed overview and reassessment of circular RNA’s potential implications in the context of axolotl limb regeneration, particularly in relation to the interaction with miRNAs. Moreover, this paper shows the utility and significance of the axolotl model organism as a valuable resource for the study of limb regeneration mechanisms. Furthermore, the study delves into the methodology and theoretical underpinnings behind the identification and mapping of circular functional genes, which is an integral step in understanding their specific contributions to the process of limb regeneration. The outcomes of this research could probably provide a solid foundation for future studies on limb regeneration, as well as a deeper understanding of the complex regulatory mechanisms that underlie this biological process.
Targeted ACE inhibitors for the Treatment of Dilated Cardiomyopathy (DCM)
Authors: Xu Yuehan
Published: February 2025

Dilated cardiomyopathy, a subtype of cardiomyopathies characterized by ventricular dilation, particularly of the left or both ventricles, coupled with systolic impairment, represents a heterogeneous condition distinct from valvular heart disorders, congenital cardiac anomalies, hypertensive cardiomyopathy, and acyanotic heart diseases. This article explores the varied categories of angiotensin-converting enzyme (ACE) inhibitors and their precise molecular targets. As a relatively uncommon disease entity, dilated cardiomyopathy lacks a definitive pharmacological cure and is managed primarily through medical therapy or surgical interventions. Emerging therapeutic modalities, such as left ventricular assist device (LVAD) support, have been introduced, yet the majority of these treatments necessitate careful consideration due to their specific indications and potential implications. Keywords: dilated cardiomyopathy, drug targeting, ACE inhibitors
From Hindrance to Growth: The Role of Life Meaning and Automatic Thinking in the Challenge-Hindrance Stress Framework
Authors: Wang Qiyue
Published: February 2025

This study explores the intricate relationship between perceived stress and happiness among adolescents through the lens of the Challenge-Hindrance Stress Framework. Utilizing a sample of 103 Chinese high school students, it investigates how distinct stressors types influence subjective well-being and examines the interplay of Negative Automatic Thinking (NAT) and Perceived Meaning of Life (PML). Findings reveal that higher stress levels are generally linked to lower subjective well-being (SWB), while challenge stressors might slightly promote SWB and hindrance stressors impede SWB, supporting the Challenge-Hindrance Stress Framework. Also, higher sense of meaning is associated with greater happiness. Additionally, Negative Automatic Thinking (NAT) scores are positively correlated with both Challenge and Hindrance stressors, with a stronger association observed between NAT and Hindrance stressors. This research contributes to the growing body of literature by highlighting the cultural dimensions of stress appraisal and suggesting directions for future studies on resilience-building interventions and cross-cultural comparisons.
Examining the Influence of Ambient Sounds on Visual Attention and Search Performance
Authors: Zhu Mingyang
Published: February 2025

In sports competitions, ambient sounds, such as audience cheering and booing, can influence athletes’ performance, either positively or negatively. Cheering is typically seen as supportive and performance-enhancing, while booing is perceived as depressing. This study investigates the effects of cheering and booing on attention and performance. Visual observation is crucial in many sports, where athletes assess situations and make decisions. This process demands increased attention and significantly impacts the outcome of the game. The study uses different levels of visual search tasks to simulate the observational phase of sports, with an eye-tracker to record participants’ gaze behaviors. Three sound environments were established: positive cheering, negative booing, and silence. Analysis of Time to First Fixation indicated that in both high-difficulty and low-difficulty tasks, participants’ search speeds were significantly slower in the cheering and booing conditions compared to silence. Moreover, in high-difficulty tasks, positive cheering disrupted performance more than negative booing. Further analysis of Average Fixation Duration revealed no significant difference between cheering and booing in terms of cognitive load on participants, suggesting that the interference caused by sound is due to attention disruption rather than cognitive overload. The study’s findings provide quantitative and precise data via eye-tracking technology. These results offer scientific insights for enhancing training and competition environments to help athletes perform better. Additionally, the findings suggest that audiences should minimize their interference with athletes by refraining from making noise during moments requiring high concentration in the game.
The Cardioprotective Effects of Vaccinations: An Integrative Analysis
Authors: Cao Hanwei , Pan Yiqiu , Yin Guoliang
Published: February 2025

This study examines the relationship between vaccinations (influenza, pneumonia, tetanus, and COVID-19) and heart disease prevalence using data from the Behavioral Risk Factor Surveillance System (BRFSS). Using logistic regression and Random Forest Classification (RFC) models, the study identified key predictors of cardiovascular disease (CVD). The RFC model demonstrated high accuracy (93.89%) and suggested that vaccinations may reduce CVD risk, though pre-existing health conditions could influence results. The study concludes that vaccinations may be valuable in reducing CVD risk and calls for further research to confirm these findings and understand the mechanisms involved.
Association between three thyroid disruptors and sleep quality with the interacting role of vitamins and cholesterol
Authors: Jin Yanjun , Su Weile
Published: February 2025

Sleep quality is one critical indicator of human health and sleep-associated diseases are threatening the health condition of a significant proportion of the population. To resolve sleep disorder, many studies have explored on the effect of nutrient intake but few concentrated on the role of biochemical components within human’s body. Consequently, this study aims to explore the association of multiple biochemical components with sleep quality and therefore, contribute to future medications on sleep disorders. Data was extracted from NHANES 2017-2018 dataset and multiple models are constructed respectively to investigate the associations between perchlorate, nitrate, and thiocyanate exposures, and the risk of sleep disorder. Thiocyanate was observed to be significantly associated with sleep disturbance in both unadjusted (p=0.0278) and adjusted model (p=0.0421) while perchlorate (p=0.0257) and nitrate (p=0.0103) are merely significantly correlated with sleep disturbance in the adjusted model. Since causal relationships cannot be established, future studies are expected to explore underlying causal association and therefore, apply on medications targeting sleep disorders.
Application of the system for the net utilization of energy and protein through the „Clarcs“ indices in dairy cattle breeding
Authors:   Agricultural University –Plovdiv, Bulgaria, Penkov Dimo , Ganchev Gancho ,   Trakia University –Stara Zagora, Faculty of Agriculture, Department of Fundamental Sciences in Animal husbandry, Mihaylova Milena ,   Agricultural Academy, Agricultural Institute – Stara Zagora, Bulgaria
Published: February 2025

A methodology for calculating the net utilization of energy and protein along the feed-cow’s milk
chain by using the Clarc energy distribution (CED) and Clarc protein transformation (CPT) criteria was adapted.
Data from experiment with elite cows of the Bulgarian Black-and White cattle breed during the first 100 days
of lactation were used as a basis.
The obtained CED (average 0.5766 with periodic variations between 0.5275 and 0.6178) and CPT (average
0.9104 with periodic variations between 0.8324 and 0.9984) reflect the highest transformations of net energy
and protein digestible in the intestine from forage into gross energy and crude protein of direct consumed from
human product, compared to other domestic animal products.
Risk status of semi-arid Zimbabwean indigenous cattle populations under conservation programs
Authors:   Makoholi Research Institute,Innovation & Development Directorate, Department of Agricultural Research, Masvingo, Zimbabwe, Gwatirisa Calisto , Moyo Sizo ,   Lupane State University, Faculty of Agricultural Sciences, Department of Animal Science and Rangeland Management, Lupane, Zimbabwe, Mudereri Bester T. ,   International Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya, Mudziwapasi Reagan ,   Lupane State University, Faculty of Agricultural Sciences, Department of Animal Science and Rangeland Management, Lupane, Zimbabwe, Munengwa Anderson ,   Marondera University of Agricultural Sciences and Technology, Faculty of Plant and Animal Sciences and Technology, Department of Animal Production Sciences, Marondera, Zimbabwe, Pullen Jessica ,   Lupane State University, Faculty of Agricultural Sciences, Department of Animal Science and Rangeland Management, Lupane, Zimbabwe, Mugoti Alban ,   Lupane State University, Faculty of Agricultural Sciences, Department of Animal Science and Rangeland Management, Lupane, Zimbabwe, Jomane Fortune N. ,   Lupane State University, Faculty of Agricultural Sciences, Department of Animal Science and Rangeland Management, Lupane, Zimbabwe
Published: February 2025

Indigenous cattle breeds play a crucial role in most agricultural systems, providing sustainable
livelihoods, cultural value, and genetic diversity, well-suited to semi-arid environments. The study aimed to
assess the population structure and risk status of three indigenous beef cattle breeds, Tuli, Mashona, and Nkone,
focusing on effective population size (Ne), number of females (L), and additional risk factors. Pedigree records
for 37,081 Tuli, 12,935 Mashona, and 9,489 Nkone cattle were analyzed using the online POPREP software.
Pedigree completeness over six generations varied, with the lowest completeness observed in the Nkone (23.2%),
and the highest in the Mashona (25.9%). Average generation intervals ranged between 6.4 and 11.0 years, with
inbreeding rates per generation of 0.26% for Mashona, 0.32% for Tuli, and 0.18% for Nkone. Effective population
sizes were estimated at 266 for Tuli, 182 for Mashona, and 135 for Nkone, classifying Mashona and Nkone
populations as endangered and in need of conservation, while Tuli requires ongoing monitoring. Additional
risk factors, including geographic concentration and cultural value, further confirm the endangered status of
these breeds. These findings highlight the critical need to strengthen conservation efforts to preserve the genetic
diversity of Zimbabwe’s indigenous cattle populations.
The Use of Peer Assessment and Non-Scripted Role-Play Activities in Improving Thai EFL High School Students’ English Oral Performance
Authors: Tsai Cheng-Chun , Piamsai Chatraporn
Published: February 2025

This study explored the effectiveness of integrating peer assessment (PA) and non-scripted role-play (NSRP) activities in enhancing the oral performance of Thai EFL high school students. Conducted at a public secondary school in Bangkok, the research involved 31 Grade 12 students and utilized a mixed methods approach. Over nine weeks within the “Research Methods and Presentation Skills” course, the intervention included training sessions, a speaking rubric, an attitude questionnaire, and semi-structured interviews. Data analysis encompassed quantitative methods like t-tests and qualitative methods such as thematic analysis. The findings demonstrated that PA and NSRP activities significantly enhanced oral performance by fostering speaking skills, cultural competence, and self-awareness. NSRP activities improved speaking complexity, accuracy, and fluency through real-life communication scenarios, enhancing motivation via authentic interactions. PA complemented NSRP by promoting collaborative learning, self-reflection, and critical self-evaluation. Pedagogically, effective implementation of PA and NSRP aligned with communicative language teaching principles, integrated digital literacy, and accommodated learner diversity.
Governing in a Hybrid Space: The Nexus of Islam, Culture, and Power in Probolinggo, East Java
Authors: Sair Abdus , . Aribowo , Kusman Airlangga Pribadi
Published: February 2025

Probolinggo, East Java, represents a hybrid space where Islam, local culture, and political power intersect, shaping socio-political dynamics. The region blends Javanese and Madurese traditions, fostering flexibility in religious practices and political strategies. Using a qualitative approach, this study examines historical, socio-cultural, and religious factors influencing leadership and governance. Findings reveal that political legitimacy is shaped not only by democratic mechanisms but also by religious and cultural authority. Pilgrimages to religious graves and affiliations with pesantren play vital roles in political networking and community relations. This study argues that Probolinggo's hybridity offers a model for understanding the interplay of Islam, culture, and power in local democracy. It highlights how religious and cultural flexibility serves as a political strategy to maintain legitimacy in governance. This research contributes to discussions on multicultural societies and governance in Indonesia and similar contexts.
Desarrollo e implementación de un clasificador espectral para la discriminación de superficies terrestres y acuáticas utilizando datos de sentinel 2 y técnicas de aprendizaje automático
Authors:   Instituto Tecnológico Superior de Guasave, Bojórquez Delgado Jesús , Bojórquez Delgado Gilberto ,   Instituto Tecnológico Superior de Guasave, Flores Rosales Manuel Alfredo ,   Instituto Tecnológico Superior de Guasave
Published: February 2025

La clasificación precisa de superficies terrestres y acuáticas es fundamental para la gestión de recursos naturales, con aplicaciones en la agricultura de precisión y la gestión del agua. Este estudio desarrolló e implementó un clasificador espectral utilizando datos de Sentinel-2 y técnicas avanzadas de aprendizaje automático, evaluando algoritmos como CNN 1D, MLP, LSTM, GBM y Random Forest. Los resultados mostraron que el modelo CNN 1D alcanzó una precisión, recall y F1-score del 100 %, superando otros métodos tradicionales. La capacidad del modelo para capturar características espaciales complejas de los datos espectrales fue clave para su rendimiento.
KESENJANGAN TEKNOLOGI DAN TRANSFORMASI SOSIAL: STUDI PENGARUH AI PADA PENDIDIKAN DI BATAM
Authors: Suhartono Tony
Published: February 2025

This study aims to analyze the impact of inequality in access to technology on student motivation, engagement, and learning outcomes in Batam, as well as explore the influence of artificial intelligence (AI) on their social skills. Inequality of access to technological devices and the internet has the potential to hinder the use of AI in education, worsen academic achievement, and widen the gap in learning and career opportunities in the future. This study uses mixed methods, with quantitative surveys to measure the level of technology access of students, teachers, and parents, as well as qualitative interviews to understand the social and emotional impact of AI use. The results of the study show that students with limited access to technology face obstacles in utilizing digital learning resources, which has an impact on motivation and academic achievement. Although AI is able to improve learning personalization, its use also poses new challenges, such as the decline in direct communication capabilities due to the dominance of digital interactions. Based on these findings, the study recommends strategic measures, such as improving technology infrastructure, device lending programs, and digital skills training for students and teachers. The conclusion of the study emphasizes the need for a balanced approach between technology and social skills development to create an inclusive and equitable learning environment. The implication is that education policies need to support equal access to technology and smart technology integration, so that all students can take optimal advantage of the potential of AI without losing essential social skills in facing the challenges of the modern era
Trachyspermum ammi (Ajwain): A comprehensive review of pharmacological property from traditional to recent developments
Authors:   Bioprospection and Product Development Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, Uttar Pradesh, India, Baghel Surabhi , Pal Anirban
Published: February 2025

Scientific exploration of traditional knowledge and its allure use in the treatment of various ailments is one of the thrust areas of research. Herbal medicines are in excellent demand in developed as well as developing countries for primary healthcare by way of their expansive biological and medicinal benefits, higher safety borders and lower costs. In the list of medicinal plants, Trachyspermum ammi (Apiaceae) ajwain is a plant encompassing a good record as a traditional Persian and Ayurvedic cure. Essential oil obtained from fruits or seeds of ajwain, known as ‘ajwain oil,’ holds various phytoconstituents and shows numerous biological and pharmacological properties. The present review aims to investigate the medical significance of different diseases and metabolic disorders in human beings. The ajwain seeds and their extracts contain different chemical constituents, including thymol (a principal constituent), β-pinene, α-terpinene, α-pinene, p-cymene, γ-terpinene, etc., revealed to retain antibacterial, antifungal, antiviral, antiparasitic, antiplatelet, anti-inflammatory, antioxidant, spermicidal, antiepileptic, antitussive, ameliorative, antihypertensive, antispasmodic and anti-hyperlipidemic effects. They also show digestive stimulant and gastro-protective properties as well as broncho-dilatory effects. Due to the presence of a broad spectrum of pharmacological properties, this plant holds good potential for its utilization in novel pharmaceutical preparations in the future. The present review is, therefore, an effort to summarize the detailed literature on phytochemical constituents and the pharmacological properties of T. ammi to explore its possible therapeutic application.

Keywords: Essential oil, Trachyspermun ammi, Herbal medicine, Pharmacological property, ajwain
Tea flavonoids: A Promising ally against Alzheimer’s and Parkinson’s diseases
Authors:   Institute of Biosciences and Technology, Shri Ramswaroop Memorial University (SRMU), Deva Road, Lucknow, Uttar Pradesh-225003, India, Joshi Pritika , Tiwari Vidyanand
Published: February 2025

Tea is one of the most popular beverages consumed worldwide, which has several bioactive compounds with potential health advantages. The primary bioactive compounds in tea are phenolic compounds with one or more aromatic rings bearing hydroxyl, and these are classified as secondary metabolites. This comprehensive review delves into the intricate relationship between tea polyphenols and their potential role in shielding the brain from neurodegenerative diseases, focusing specifically on Alzheimer’s and Parkinson’s. It kicks off by offering an overview of tea’s cultural importance and diverse varieties. The exploration then delves into the complex biochemistry of tea, emphasizing the presence of flavonoids, such as epigallocatechin gallate (EGCG) in green tea and theaflavin and thearubigins in black tea, recognized for their powerful antioxidant and anti-inflammatory properties. Acknowledging the widespread occurrence and severe consequences associated with Alzheimer’s and Parkinson’s diseases, the article underscores a focus on shared pathophysiological processes inherent in these disorders, encompassing protein aggregation, oxidative stress, and neuroinflammation. The current symptomatic relief provided by medicines necessitates the search for alternative approaches. Promisingly, tea flavonoids emerge as candidates capable of addressing the underlying mechanisms of neurodegenerative diseases. These compounds may enhance the growth of nerve cells and improve connections between them, offering a potential avenue for developing therapies for neurodegenerative diseases. The article examines existing literature, providing insights into the potential therapeutic effects of tea polyphenols, aiding our understanding of how these substances might slow down Alzheimer’s and Parkinson’s by studying their intricate interactions in our bodies. In summary, this detailed review combines historical context, complex chemistry, and neurological effects, offering a holistic view of how tea polyphenols might protect the brain. The findings presented herein lay the foundation for future research and therapeutic strategies, showcasing the potential benefits of tea in combating neurodegenerative diseases worldwide. The authors aim to explore existing research on tea, examining its health benefits and its relationship with different lifestyle-related diseases.

Keywords: Tea, Catechins, Flavonoids, Bioactive compounds, Neuroprotective diseases, Alzheimer’s disease, Parkinsons disease
Human-elephant conflict: Role of medicinal and aromatic plants in mitigating HEC and ensuring livelihood sustainability
Authors: Yogendra Naraganahalli Dasappa , Kumara Rajesh Ravi , Prakash Thankaswamy Arul , Keerthi Paddambail Ellianna , Kumar Dipender , Pragadheesh Vppalayam Shanmugam
Published: February 2025

CSIR-Central Institute of Medicinal and Aromatic Plants, Research Centre, Bangalore-560065, India.
Ocular Findings in a Patient with Type 1 Myotonic Dystrophy: A Case Report
Authors: Canellos Harriette , Kowalsky Moskaliuk Daniel , Bass Sherry
Published: February 2025

Patients with DM1 can present with multiple complex ocular findings such as cataracts, corneal dystrophies, ptosis, and epiretinal membranes....
Muriendo de Éxito
Authors: Roberts Martínez Marion , Martinez Martinez Luz , Cuesta Cambra Ubaldo
Published: February 2025

El fenómeno de los pisos turísticos en Madrid es un reflejo de las tensiones entre la economía globalizada del turismo y las necesidades locales de vivienda y convivencia social. Si bien el turismo es un motor económico crucial para la ciudad, su crecimiento desmedido a través de plataformas digitales ha generado una serie de problemas como la gentrificación, el encarecimiento de la vivienda, la inseguridad y el rechazo. En este contexto, las herramientas de comunicación y place marketing son elementos clave para abordar esta problemática de manera sostenible. Este artículo explora el flujo comunicacional sobre los pisos turísticos en Madrid y su percepción de conflictivo en relación con el ayuntamiento y la necesidad de estrategias de comunicación eficientes y place marketing.
Los desafíos en las conmemoraciones históricas
Authors: Muñoz Sastre Daniel
Published: February 2025

Las recreaciones históricas se han convertido en elementos estimuladores de la actividad cultural de aquellos lugares en los que se desarrollan. La conmemoración en Segovia (España) del 550 aniversario de la proclamación de Isabel I como reina de Castilla es un ejemplo de este tipo de eventos. Para recordar esa efeméride, el ayuntamiento de esta ciudad en la que se celebró dicho acontecimiento organizó un programa de actividades. Este trabajo plantea un estudio cualitativo de dicha conmemoración a través de una revisión de documentos y observaciones participativas en torno a la organización de esos actos. Esta investigación demuestra las características de este tipo de eventos y el desafío de aquellos que lo organizan. Ese reto no es otro que el de encontrar la armonía entre la autenticidad histórica y la adaptación a los valores actuales, asegurando que las celebraciones continúen siendo significativas para las generaciones futuras.