bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethnohistory and Historical Ethnography
Authors: Douglas Bronwen , Di Rosa Dario
Published: March 2020

This article situates ethnohistory historically, conceptually, methodologically, and geographically in relation to its intertwined “parent” disciplines of anthropology and history. As a named interdisciplinary inquiry, ethnohistory emerged in the United States in the mid-1950s in the “applied” context of academic involvement in Native American land claims hearings after 1946. However, anthropology (the science of humanity) has overlapped, intersected, or diverged from history (study or knowledge of the past) since becoming a distinct field in Europe in the mid-18th century and gradually professionalized as an academic discipline from the 1830s, initially in Russia (see Before Boas: The genesis of ethnography and ethnology in the German Enlightenment [Lincoln: Univ. of Nebraska Press, 2015], cited under Anthropology and History). Anthropological approaches oscillated between historicization and its neglect or denial, with recurring tension between event and system, process and structure, diachrony and synchrony. In the late 18th and 19th centuries, ethnology (comparative study of peoples or races, their origins and development) was distinguished from the natural history of man and from anthropology (the science of race), initially in France. From the 1860s to the 1920s, Anglophone anthropological theory was dominated by the opposed doctrines of sociocultural evolution and diffusion—both superficially historical but largely ahistorical processes. For the next half century, prevailing functionalist, structuralist, and culturalist discourses mostly denied knowable history to ethnography’s purportedly vanishing “primitive” subjects. This uneven, agonistic disciplinary history did not encourage a subfield uniting anthropology and history. However, after 1950, in global contexts of anticolonialism, decolonization, and movements for Indigenous or egalitarian rights, anthropologists, historians, and archaeologists developed the hybrid fields of Ethnohistory and Ethnographic History, which flourished for half a century. Practitioners transcended ethnohistory’s spatial and conceptual roots in the United States and Canada to investigate Indigenous or African American pasts in Latin America and the Caribbean, Indigenous or local pasts in Africa, Asia, and Oceania, and non-Indigenous pasts in Europe and elsewhere. The need to incorporate Indigenous or popular histories and viewpoints was increasingly emphasized. From the 1980s, ethnohistory was condemned as Eurocentric, outdated, even racist, by postcolonial and postmodern critiques (see: The state of ethnohistory. Annual Review of Anthropology 20 (1991):345–375, cited under General Overviews). The label’s usage declined in the 21st century in favor of the already established terms anthropological history or historical anthropology, or the emergent fields of Anthropology of History, historical consciousness, and historicity.
Philosophy of Museums
Authors: Harrison Victoria S. , Tonner Philip
Published: March 2020

Museums and their practices of collection, curation, and exhibition raise a host of philosophical questions. The philosophy of museums is a relatively new and growing subdiscipline within the academic field of philosophy. While only recently taking shape as a distinct area, this subdiscipline builds upon a tradition of interest in museums that has been taken up by prominent philosophers, such as Theodor Adorno (Prisms 1967) and Michel Foucault (Aesthetics, Method, and Epistemology 1998). Philosophers active in the philosophy of museums are less concerned with intra-disciplinary differences (between, e.g., “continental philosophy” and “analytic philosophy” and their recent permutations) than they are with thinking about the museum on its own terms as a phenomenon calling for philosophical engagement. Indeed, as Beth Lord put it, the basic conviction among scholars in this area is that “philosophy can help us to think about museums, [and] . . . that museums can contribute to philosophical thinking” (Philosophy and the museum. Museum Management and Curatorship 21.2 (2006): 80). As such, the promise of the philosophy of museums is that, despite it being a subfield of a larger discipline, it will enable a fresh look at its parent discipline while also prompting the development of new perspectives on more traditional philosophical questions. Philosophical approaches will also help us to understand museums and their objects in myriad new ways, as this emerging discipline within the broad church of philosophy matures over the coming years. Although many of the philosophical questions raised by museums are ethical, the philosophy of museums goes beyond the confines of any single established area of philosophy, such as ethics, aesthetics, or metaphysics. Work within the philosophy of museums thus now ranges over themes such as philosophical museology, the epistemological and ethical dimension of humanity and social life, culture, and religion, as well as those more directly connected to issues arising from museum practices of curation, conservation, and exhibition. The philosophy of museums is not entirely independent of scholarship within the field of museum studies, therefore, this article makes reference not only to works that are philosophical in a narrow sense but also to work of philosophical interest within museum studies and more occasionally to scholarship within other disciplines such as anthropology and history.
Eastern European Television
Authors: Imre Anikó
Published: March 2020

The field of television studies has given us a rich tapestry of the history and theory of the dominant commercial model that developed in the United States, and of the public broadcasting model that defined Western European television systems, through the 1980s. However, substantial work on the histories of Eastern European and (post)Soviet broadcasting has only appeared in English in the new millennium. To some extent, this absence of work on (post)socialist television has been due to a shortage of information about socialist cultures. Other reasons include television studies’ own identification of American TV as the normative path of the medium’s development, supported by a Cold War ideological filter toward (post)socialist cultures, which equated socialist TV with propaganda, as well as television’s status in Eastern Europe as a “lowly” popular medium not worthy of serious study. Recent publications have finally challenged the lingering stereotypes about socialist systems and introduced a different model of television into the study of the media. They have shown that, while socialist television systems varied significantly in terms of language, cultural tradition, political attitudes, and economic development, Eastern European and Soviet TV welcomed a range of innovative aesthetic practices and involved hybrid economic models. It fostered frequent exchanges and collaborations within the region and with Western media institutions, a programming flow across borders, a steady production of genre entertainment, in some cases significant reliance on commercial revenue, and transcultural reception practices along the shared broadcast signals of national borders. Rather than homogeneity and brainwashing, the history of Eastern European television shows affinity and collaboration with Western European public broadcasters; socialist party leaderships’ more or less haphazard attempts at control, which was constantly tempered by the demands of viewers to be entertained; the crucial role of competition as a driving force;, and experiments with various forms and genres in an effort to convey authenticity and persuasion. With transnational conglomerates’ rapid takeover of postsocialist media markets in the 1990s, and the accession of most former socialist states into the European Union in the mid-2000s, the story of Eastern European television has officially become a part of that of European TV and, more broadly, of the globalization of the media industries. What still justifies a regional approach are simultaneous political-economic developments that have once again shaped the region’s media in similar ways: after a short period of hard-fought reforms over media ownership and regulation in the 1990s, Europe’s financial crises in the late 2000s gravely affected postsocialist media economies and prepared television for a new type of re-centralization under the control of illiberal national oligarchies in coexistence with global neoliberal competition and consumer access to media content from around the world.
Follow-up survey of patients with occupational asthma
Authors: Feary J , Cannon J , Fitzgerald B , Szram J , Schofield S , Cullinan P
Published: March 2020

Background

Occupational asthma (OA) is often associated with a poor prognosis and the impact of a diagnosis on an individual’s career and income can be significant.

Aims

We sought to understand the consequences of a diagnosis of OA to patients attending our clinic.

Methods

Using a postal questionnaire, we surveyed all patients attending our specialist occupational lung disease clinic 1 year after having received a diagnosis of OA due to a sensitizer (n = 125). We enquired about their current health and employment status and impact of their diagnosis on various aspects of their life. Additional information was collected by review of clinical records.

Results

We received responses from 71 (57%) patients; 77% were referred by an occupational health (OH) provider. The median duration of symptoms prior to referral was 18 months (interquartile range (IQR) 8–48). At 1 year, 79% respondents were no longer exposed to the causal agent. Whilst the unexposed patients reported an improvement in symptoms compared with those still exposed (82% versus 53%; P = 0.023), they had poorer outcomes in terms of career, income and how they felt treated by their employer; particularly those not currently employed. Almost all (>90%) of those still employed had been referred by an OH provider compared with 56% of those currently unemployed (P = 0.002)x.

Conclusions

The negative impact of OA on people’s careers, livelihood and quality of life should not be underestimated. However, with early detection and specialist care, the prognosis is often good and particularly so for those with access to occupational health.
Indirect Detection of Burkholderia pseudomallei Infection in a US Marine After Training in Australia
Authors: Larson Derek T , Schully Kevin L , Spall Ammarah , Lawler James V , Maves Ryan C
Published: March 2020

In 2012, the United States Marine Corps began annual deployments around Australia, including highly endemic areas for Burkholderia pseudomallei. B. pseudomallei infection, or melioidosis, is difficult to diagnose, and culture remains the gold standard. Accurate and timely diagnosis is essential, however, to ensuring appropriate therapy. Ten days after returning from Australia, a Marine presented to a community hospital with massive cervical lymphadenopathy, fever, and cough. Computed tomography demonstrated scattered pulmonary infiltrates with small cavitations; lymphadenopathy involving the cervical, supraclavicular, and mediastinal nodes; and splenomegaly. Sputum and blood cultures were negative. Empiric antimicrobial therapy with ceftazidime was initiated for suspected melioidosis. Retrospectively, a prototype iSTAT cartridge modified to detect B. pseudomallei capsular polysaccharide antigen was used to test a specimen of the patient’s blood and was determined to be positive. Over the course of therapy, B. pseudomallei capsular antigen levels in blood declined as the patient improved. The leveraging of an existing point-of-care (POC) analyzer to create a rapid diagnostic assay for melioidosis provides a template for rapid POC diagnostics that could significantly improve the ability of clinicians to deliver timely and appropriate therapy for serious infections.
FOREST unbiased Galactic plane imaging survey with the Nobeyama 45 m telescope (FUGIN). VII. Molecular fraction of H i clouds
Authors: Nakanishi Hiroyuki , Fujita Shinji , Tachihara Kengo , Izumi Natsuko , Matsuo Mitsuhiro , Umemoto Tomofumi , Oasa Yumiko , Inoue Tsuyoshi
Published: March 2020

We analyze molecular-gas formation in neutral atomic hydrogen (H i) clouds using the latest CO data, obtained from the FOREST (four-beam receiver system on the 45 m telescope) unbiased Galactic plane imaging survey with the Nobeyama 45 m telescope, and using H i data taken from the Very Large Array Galactic plane survey. We applied a dendrogram algorithm to the H i data cube to identify H i clouds, and we calculated the H i mass and molecular-gas mass by summing the CO line intensity within each H i cloud. On the basis of the results, we created a catalog of 5737 identified H i clouds with local standard of rest (LSR) velocity of VLSR ≤ −20 km s−1 in galactic longitude and latitude ranges of 20° ≤ l ≤ 50° and −1° ≤ b ≤ 1°, respectively. We found that most of the H i clouds are distributed within a Galactocentric distance of 16 kpc, and most of them are in the cold neutral medium phase. In addition, we determined that the high-mass end of the H i mass function is fitted well with a power-law function with an index of 2.3. Although two sequences of self-gravitating and diffuse clouds are expected to appear in the M tot–$M_{\,{\rm H}_2}$ diagram according to previous works based on a plane-parallel model, the observational data show only a single sequence with large scattering within these two sequences. This implies that most of the clouds are mixtures of these two types of clouds. Moreover, we suggest the following scenario of molecular-gas formation: an H i-dominant cloud evolved with increasing H2 mass along a path of $M_{\,{\rm H}_2} \propto M_{\,\rm tot}^2$ by collecting diffuse gas before reaching and moving along the curves of the two sequences.
Effectiveness and safety of 12-month certolizumab pegol treatment for axial spondyloarthritis in real-world clinical practice in Europe
Authors: Baraliakos Xenofon , Witte Torsten , De Clerck Luc , Frediani Bruno , Collantes-Estévez Eduardo , Katsifis Gkikas , VanLunen Brenda , Kleine Elisabeth , Hoepken Bengt , Bauer Lars , Goodson Nicola
Published: March 2020

Objectives

The efficacy and safety of certolizumab pegol (CZP), an Fc-free, PEGylated anti-TNF, in axial spondyloarthritis (axSpA) has been established in clinical trial settings. We report CZP effectiveness and safety in European clinical practice in patients with axSpA, including radiographic (r-) and non-radiographic (nr-) axSpA.

Methods

CIMAX (NCT02354105), a European non-interventional multicentre prospective study, observed CZP treatment response and safety over 12 months in a real-world axSpA cohort. The primary outcome was change from baseline in BASDAI to week 52, with additional outcomes pertaining to effectiveness and safety. Patients who received ≥1 dose CZP were followed up for adverse events, and those with baseline and ≥1 post-baseline BASDAI assessment were included in effectiveness analyses.

Results

A total of 672 patients (r-axSpA: 469; nr-axSpA: 201; unconfirmed diagnosis: 2) from 101 sites received ≥1 dose of CZP, of whom 564 (r-axSpA: 384; nr-axSpA: 179; unconfirmed: 1) were included in the effectiveness analyses. The mean baseline BASDAI was 6.1 in the overall axSpA population and r-axSpA and nr-axSpA subpopulations. At week 52, the mean (s.d.) change in BASDAI was −2.9 (2.3; n = 439); for r-axSpA and nr-axSpA, it was −2.9 (2.2; n = 301) and −2.8 (2.4; n = 137), respectively (P <0.0001 for all). Similar improvements were seen across other axSpA disease measures. In total, 37.9% (255/672) patients experienced adverse events, and 1.8% (12/672) experienced ≥1 serious adverse events.

Conclusion

Improvements observed in signs and symptoms of axSpA following one year of CZP treatment in real-world clinical practice were similar to those from previous randomized clinical trials, with no new safety concerns.
A novel treatment for psoriatic arthritis: Janus kinase inhibitors
Authors: Chen Miao , Dai Sheng-Ming
Published: March 2020

Psoriatic arthritis (PsA) is a type of chronic inflammatory arthritis which is associated with psoriasis. The early recognition and treatment for PsA are of critical importance. Janus kinase (JAK) inhibitors, as a kind of orally small molecules, have emerged as an encouraging class of drug in PsA treatment. This review provides a discussion of the role and current status of JAK inhibitors in the control of PsA. There are three JAK inhibitors approved for use in autoimmune diseases, for example, tofacitinib, baricitinib, and upadacitinib, and only tofacitinib has been approved in PsA treatment. The clinical trials of upadacitinib and filgotinib in PsA patients are undergoing. The efficacy and safety of these agents were briefly discussed. Although there are still issues in terms of their efficacy and safety currently, JAK inhibitors are expected to benefit more PsA patients in future.
Identification of populations likely to benefit from pharmacogenomic testing
Authors: Heise Craig William , Gallo Tyler , Curry Steven C. , Woosley Raymond L.
Published: March 2020

Objectives

Pharmacogenomic testing (PGX) implementation is rapidly expanding, including pre-emptive testing funded by health systems. PGX continues to develop an evidence base that it saves money and improves clinical outcomes. Identifying the potential impact of pre-emptive testing in specific populations may aid in the development of a business case.

Methods

We utilized a software tool that can evaluate patient drug lists and identified groups of patients most likely to benefit from implementation of a PGX testing program in a major medical system population.

Results

Medication lists were obtained for sixteen patient groups with a total of 82 613 patients. The percent of patients in each group with testing ‘Recommended’, ‘Strongly recommended’, or ‘Required’ ranged from 12.7% in the outpatient pediatric psychiatry group to 75.7% in the any adult inpatient age >50 years group. Some of the highest yield drugs identified were citalopram, simvastatin, escitalopram, metoprolol, clopidogrel, tramadol, and ondansetron.

Conclusion

We demonstrate a significant number of patients in each group may have benefit, but targeting certain ones for pre-emptive testing may result in the initial highest yield for a health system.
Assessment of Epidemiological Trends in Craniosynostosis: Limitations of the Current Classification System
Authors: Gonzalez Santiago R. , Light Jeremy G. , Golinko Michael S.
Published: March 2020

Background:

Craniosynostosis affects 1 in 2,000 live births, which makes it one of the most common craniofacial abnormalities in the United States. Despite this fact, few national epidemiologic reports exist, although US and European studies have reported an increased incidence of metopic craniosynostosis. The aim of our study is to analyze the National Inpatient Sample (NIS) to support those conclusions.

Methods:

We identified hospitalizations from 1998 to 2012 by using the ICD-9-CM diagnosis code for congenital anomalies of skull and face bones (756.0) and procedure codes related to craniosynostosis repair (2.01, 2.03, 2.04, 2.06).

Results:

We analyzed data from 37,815 hospitalizations and 49,505 reconstructive procedures. There was a 61.6% increase in the number of hospitalizations related to craniosynostosis repairs. There was a 180% increase in bone graft to skull procedures, 109% increase in other cranial osteoplasty, 54% increase in formation of cranial bone flap, and a 6% decrease in opening of cranial suture.

Conclusions:

We observed a steady rise in the number of craniosynostosis repairs performed, but whether this is a result of a true increase in incidence, better diagnosis, or change in treatment patterns needs further research. The current classification system does not provide information about the specific suture affected (metopic, sagittal, etc.), the type of repair performed (endoscopic, fronto-orbito advancement, etc.), and whether the repair is a primary procedure or a revision. More descriptive diagnosis and procedural codes are imperative to improve the epidemiologic and outcomes data of craniosynostosis in the United States.
Targeted Muscle Reinnervation Combined with a Vascularized Pedicled Regenerative Peripheral Nerve Interface
Authors: Valerio Ian , Schulz Steven A. , West Julie , Westenberg Ritsaart F. , Eberlin Kyle R.
Published: March 2020

Symptomatic neuromas and pain caused by nerve transection injuries can adversely impact a patient’s recovery, while also contributing to increased dependence on opioid and other pharmacotherapy. These sources of pain are magnified following amputation surgeries, inhibiting optimal prosthetic wear and function. Targeted muscle reinnervation (TMR) and regenerative peripheral nerve interfaces (RPNI) represent modern advances in addressing amputated peripheral nerves. These techniques offer solutions by essentially providing neuromuscular targets for transected peripheral nerves “to grow into and reinnervate.” Recent described benefits of these techniques include reports on pain reduction or ablation (eg, phantom limb pain, residual limb pain, and/or neuroma pain).
1–6
We describe a technical adaptation combining TMR with a “pedicled vascularized RPNI (vRPNI).” The TMR with the vRPNI surgical technique described offers the advantage of having a distal target nerve and a target muscle possessing deinnervated motor end plates which may potentially enhance nerve regeneration and muscle reinnervation, while also decreasing amputated nerve-related pain.
Intraosseous Ganglion Cyst of the Sternoclavicular Joint
Authors: Maeba Takahiro , Kahara Naoaki
Published: March 2020

We report the case of a 63-year-old man who presented with a mass on the right clavicle near the sternoclavicular joint. He had received prior puncturing treatment, but relapsed each time. Magnetic resonance imaging revealed that the mass was a ganglion cyst, which appeared to be connected to the right clavicle. Excisional biopsy revealed that the cyst was an intraosseous ganglion cyst, and the cavity was connected to the sternoclavicular joint. The cavity was filled with an artificial bone graft after curettage to prevent fracture. Histological examination showed that the cyst wall had no lining cells and consisted of fibrous connective tissue. To the best our knowledge, this case is the first report of an intraosseous ganglion cyst of the sternoclavicular joint.
Sternocostal instability after Ravitch repair in adolescents; 3 case-reports and a review of surgical techniques in the literature
Authors: de Beer Sjoerd A. , van Heurn Ernst L. W.
Published: March 2020

Background:

Ravitch repair is a common surgical procedure to correct chest wall deformities. In this procedure, a subperichondreal cartilage resection of the deformed parasternal cartilage, and if necessary a repositioning of the sternum, is performed. Insufficient regeneration of the resected cartilage may result in sternocostal instability or even floating sternum. This rare complication presents with symptoms of pain and exercise intolerance.

Methods:

We describe sternocostal instability in 3 adolescent patients after the Ravitch procedure for pectus carinatum and reviewed the literature on this topic.

Results:

Our patients suffered different degrees of instability. In all cases, we eventually achieved a satisfactory outcome. There is little literature on sternocostal instability. It is a rare complication, mainly occurring after reoperation by damaging the perichondrium.

Conclusions:

Malunion of costal cartilage is a rare complication of open pectus repair. To achieve the best regeneration and stability of the sternum, less extended resection of cartilage should be performed and the number of cartilages resected should be limited. The perichondrium must be kept intact. Autologous grafts, growth-enhancing materials, and metal or bioabsorbable struts may contribute to stabilization and regeneration of the cartilage.
Large Viable Fat Nodules, Months Post-Transfer, inside Radiated Breast Implant Pocket: A Case Report
Authors: Hagarty Sarah E. , Santos Edward F. , Luo Jessica
Published: March 2020

The cell survival theory and the cell replacement theory contribute to the current thinking regarding free adipose graft persistence after transplantation and influence the principles applied to autologous fat transfer procedures. Both theories necessitate the reestablishment of circulation for graft survival. To minimize ischemic death, according to Khouri, fat grafts should be injected with at most 1.6-mm-wide ribbons to optimize the graft-to-recipient interface for oxygen diffusion and neovascularization. The graft is eventually incorporated into the surrounding tissue. We present a curious intraoperative finding, in a 51-year-old woman 2.5 months post-grafting for failed implant reconstruction after radiation. Several large, well-circumscribed, clearly viable adipose tissue nodules, up to 2 cm in diameter, were present inside the capsule. These were so loosely attached to the capsule of the breast pocket that a mere gentle hand sweep and irrigation after opening the cavity caused them to dislodge and float to the surface of the irrigation fluid. This finding begs additional questions about the current understanding of the mechanisms of tissue viability after grafting. It raises the clinical possibility that larger aliquots of transferred fat can be viable than previously perceived.
Systematic Review of Clinical Decision Support Systems for Prehospital Acute Coronary Syndrome Identification
Authors: Knoery Charles Richard , Heaton Janet , Polson Rob , Bond Raymond , Iftikhar Aleeha , Rjoob Khaled , McGilligan Victoria , Peace Aaron , Leslie Stephen James
Published: March 2020

Objectives:

Timely prehospital diagnosis and treatment of acute coronary syndrome (ACS) are required to achieve optimal outcomes. Clinical decision support systems (CDSS) are platforms designed to integrate multiple data and can aid with management decisions in the prehospital environment. The review aim was to describe the accuracy of CDSS and individual components in the prehospital ACS management.

Methods:

This systematic review examined the current literature regarding the accuracy of CDSS for ACS in the prehospital setting, the influence of computer-aided decision-making and of 4 components: electrocardiogram, biomarkers, patient history, and examination findings. The impact of these components on sensitivity, specificity, and positive and negative predictive values was assessed.

Results:

A total of 11,439 articles were identified from a search of databases, of which 199 were screened against the eligibility criteria. Eight studies were found to meet the eligibility and quality criteria. There was marked heterogeneity between studies which precluded formal meta-analysis. However, individual components analysis found that patient history led to significant improvement in the sensitivity and negative predictive values. CDSS which incorporated all 4 components tended to show higher sensitivities and negative predictive values. CDSS incorporating computer-aided electrocardiogram diagnosis showed higher specificities and positive predictive values.

Conclusions:

Although heterogeneity precluded meta-analysis, this review emphasizes the potential of ACS CDSS in prehospital environments that incorporate patient history in addition to integration of multiple components. The higher sensitivity of certain components, along with higher specificity of computer-aided decision-making, highlights the opportunity for developing an integrated algorithm with computer-aided decision support.
Community Health Workers Reduce Rehospitalizations and Emergency Department Visits for Low-Socioeconomic Urban Patients With Heart Failure
Authors: Vohra Adam S. , Chua Rhys F. M. , Besser Stephanie A. , Alcain Charina F. , Basnet Sweta , Battle Brenda , Coplan Mitchell J. , Liao James K. , Tabit Corey E.
Published: March 2020

Background:

Low-socioeconomic, urban, minority patients with heart failure (HF) often have unique barriers to care. Community health workers (CHWs) are specially trained laypeople who serve as liaisons between underserved communities and the health system. It is not known whether CHWs improve outcomes in low-socioeconomic, urban, minority patients with HF.

Hypothesis:

CHWs reduce rehospitalizations, emergency department (ED) visits, and healthcare costs for low-socioeconomic urban patients with HF.

Methods:

Patients admitted with acute decompensated HF were assigned to receive weekly visits by CHW after discharge. Patients were propensity score matched with controls who received usual care. HF-related rehospitalizations, ED visits, and inpatient costs were compared for 12 months following index admission versus the same period before.

Results:

Twenty-eight patients who received weekly visits from a CHW for 12 months after discharge were matched with 28 control patients who did not receive CHWs. Patients who received a CHW had a 75% decrease in HF-related ED visits (0.71 vs. 0.18 visits per patient, P < 0.001), an 89% decrease in HF-related readmissions (0.64 vs. 0.07 admissions per patient, P < 0.005), and a significant decrease in inpatient cost for HF-related visits. In controls receiving usual care, there was no significant change in hospitalizations, ED visits, or costs.

Conclusions:

In conclusion, CHWs are associated with reduced rehospitalizations, ED visits, and inpatient costs in low-socioeconomic, urban, minority patients with HF. CHWs may be a cost-effective method to reduce health care utilization and improve outcomes for this population.
Wheelchair Mobility–Related Injuries Due to Inadvertent Lower Extremity Displacement on Footplates: Analysis of the FDA MAUDE Database From 2014 to 2018
Authors: Whitford Maureen , Mitchell Steven J. , Marzloff George E. , Zindle Jennifer K. , Richmond Mary Ann , Bogie Kath M. , Henzel M. Kristi
Published: March 2020

Objectives

The aims of the study were to assess reports of wheelchair mobility–related injuries from inadvertent lower extremity displacement (ILED) on footplates, which were submitted to the Food and Drug Administration Manufacturer and User Facility Device Experience (MAUDE) database during 2014–2018, characterize injury types, and evaluate MAUDE data quality.

Methods

A systematic MAUDE database review was performed. Annual reports were searched using keywords: (a) “power wheelchair” and “injury” and (b) “mechanical (also known as manual) wheelchair” and “injury.” Reports related to injuries from ILED on the footplate were reviewed.

Results

Reports of 1075 wheelchair injuries were found across the review period. Twenty nine (3%) met our inclusion criteria. The most common source of reports was “manufacturer.” The wheelchair was unavailable for evaluation in 55.17% of reports. Manufacturers’ submission dates (number of days that passed after they were notified) ranged from 3 to 159. Reported injuries decreased by 60% from 2014 to 2018. The end user used a power wheelchair for all but one report. The most common injuries were single fractures, multiple fractures, wounds/cuts/infections, and amputations (in order of incidence). The most common mechanism was the foot slipping off the footplate during wheelchair mobility.

Conclusions

We observed inherent weaknesses in the MAUDE database reporting process and a concerning level of reporting bias. Although there were limited reports of injuries related to ILED on the footplate during wheelchair mobility, the injuries reported were significant. More standardized reporting of the mechanism and impact of these injuries is needed to better inform wheelchair design, prescription, and patient/family education.
Shoe Covers but Not Burnout? Making Burnout Reduction a Criteria for Centers for Medicare and Medicaid Services Funding Would Protect Patients
Authors: Wolpaw Jed T. , Adair Kathryn C.
Published: March 2020

In the United States, hospitals must meet eligibility criteria to receive federal funding. Regulatory bodies, such as the Joint Commission, are approved by the government to give, or withhold, accreditation to hospitals. This accreditation is a requisite to continue receiving funding. Hospitals are frequently cited for items such as inadequate wearing of boot covers or covering of facial hair in the operating rooms. There are very little, if any, data to support an improvement in patient safety when these items are complied with. There is, however, a large amount of data showing the negative consequences for patient safety when providers are burned out. We therefore propose that regulatory agencies such as the Joint Commission require that hospital systems measure burnout and reduce concerning levels of burnout in their employees to continue receiving certification. We briefly review evidence-based methods that hospital systems might consider to accomplish this goal.
Frank Sherwood ‘Sherry’ Rowland. 28 June 1927—10 March 2012
Authors: Harris Neil R. P.
Published: March 2020

Sherry Rowland was a chemist who made substantial contributions in the fields of radiochemistry and atmospheric science. He is best known for his research on the stratosphere as, with Mario Molina, he wrote the seminal paper describing how chlorofluorocarbons deplete the stratospheric ozone layer, noting that any ozone depletion would be accompanied by a consequent increase in ultraviolet radiation at the earth's surface. In 1995 he, along with Paul Crutzen, was awarded the Nobel Prize for this ground-breaking work. Sherry's career was much more rounded than this brief précis suggests. His various roles included: manager of a semi-professional baseball team while in graduate school; founding chairman of the Chemistry Department at the University of California at Irvine (UCI); tireless and effective advocate for the need to take action on chlorofluorocarbon emissions and climate change; Foreign Secretary of the National Academy of Sciences; and last, but certainly not least, devoted husband, father and grandfather.
Anthony Milner Lane. 27 July 1928—9 February 2011
Authors: Clement Charles
Published: March 2020

Tony Lane came from humble beginnings to become one of the world's leading theoretical nuclear physicists. His career in the Theoretical Physics Division at the Atomic Energy Research Establishment (AERE) at Harwell was characterized by his outstanding successes in explaining experimental nuclear data. He pioneered the understanding of the important nucleon capture reactions by introducing new mechanisms of direct and semi-direct capture and, together with colleagues, he greatly advanced knowledge of nuclear analogue states, and the role of isospin in nuclear physics. With R. G. Thomas, he wrote a comprehensive review of R-matrix theory, applied to analyse resonances in nuclear reactions, which became one of the most cited papers in physics. His book
Nuclear theory
gave a good account of the use of pairing force theory in nuclear physics, and its application to nuclear collective motion.
David Christopher Gadsby. 26 March 1947—9 March 2019
Authors: Miller Christopher
Published: March 2020

Over nearly five decades, David Christopher Gadsby pioneered biophysical research that advanced our mechanistic understanding of ion-transporting proteins in biological membranes. His passion for hands-on do-it-yourself electrophysiology, his depth of analytical rigor, and his idiosyncratic scientific aesthetic expanded the edge of discovery in two areas: the electrical character of the Na
+
pump, and the molecular workings of ‘cystic fibrosis transmembrane regulator’ (CFTR), the chloride ion channel whose mutations cause cystic fibrosis. His approach was flavoured by an appreciation for common underlying features between these ostensibly distinct types of membrane-transport systems. While David's focus was first on the basic molecular biophysics of a problem, he was always attuned to implications of his discoveries for human health. Based in New York at The Rockefeller University throughout his independent scientific career, and at the Marine Biological Laboratory in Woods Hole, Massachusetts, as a squid-season research-scientist, he was proficient in wrestling with problems spanning a wide swath of membrane biology: from determinants of the cardiac electrical waveform, to microsecond-timescale ionic currents in squid axons, to details of structure–mechanism relations in membrane pump and ion-channel proteins. He wore his eminence lightly and never distanced himself from the laboratory, where he often performed experiments with his own hands right up to his retirement. His reserved scientific personality, which demanded equally from his colleagues and himself immaculate data, unclouded logic, and substantive pertinence to the issues at hand, contrasted with his palpable joy in a good experiment and in his sea-loving life outside the lab.
Benedict Delisle Burns. 22 February 1915—6 September 2001
Authors: Richards Christopher D. , Bliss Timothy V. P.
Published: March 2020

Ben Burns was a pioneer of operations research and of the statistical analysis of neuronal activity. During the war, Ben served in Solly Zuckermann's operations research unit, which included a period of active service in the Mediterranean. After the war he worked with G. L. Brown at the National Institute for Medical Research (NIMR), where he investigated the effects of agents that affected neuromuscular transmission. In 1950 he moved to the Physiology Department of McGill University in Montreal, where he explored the properties of neural networks in neurologically isolated slabs of cerebral cortex and established the mechanisms responsible for maintaining rhythmic periods of excitation in isolated nerve networks. He subsequently provided evidence that self-re-exciting neural networks were implicated in establishing the respiratory rhythm. While at McGill, Ben initiated a number of highly original cross-disciplinary studies concerning the physiological bases of learning, memory and attention. He returned to NIMR in 1966 to head the Division of Physiology and Pharmacology, where he continued his investigations of visual perception. Ben was an ingenious experimenter and devised a number of mechanical and electronic devices for the statistical analysis of nerve cell activity at a time when digital computers were largely unavailable for biological work. In his 1968 book,
The uncertain nervous system
, he expressed his view that the interdisciplinary nature of central neurophysiology required of those who studied it a knowledge of classical physiology, experimental psychology, applied mathematics and electronic engineering. His broad view of the subject inspired a generation of students.
Raymond Charles Casey. 10 October 1917—26 April 2016
Authors: Rawson Peter F. , Rushton Adrian W. A. , Simpson Martin I.
Published: March 2020

Raymond Casey was an internationally recognized expert in two entirely different fields—geology and philately. He achieved this despite leaving school at 14. By then he was already collecting and studying fossils from his home town, Folkestone, and in 1939, despite not having a degree, he obtained a post with the Geological Survey of Great Britain in the modest role of assistant to C. J. Stubblefield. After war-time service in the RAF, he returned to the Survey in a similar role, but spent much of his ‘spare time’ researching and publishing on Lower Cretaceous palaeontology and stratigraphy. His fortunes began to change when, at the age of 38, he was admitted to Reading University to study for a doctorate. His thesis on Lower Greensand stratigraphy and palaeontology was recognized as an outstanding study that led to major publications including a nine-part monograph of the ammonite faunas. Then, in the late 1950s, he also began to study faunas from Jurassic–Cretaceous boundary beds in eastern England as part of his official work and this led to him visiting the Soviet Union on several occasions from 1963 onward. On the first visit he met the academician Nalivkin in Leningrad, who, as well as being an eminent geologist, was a keen philatelist. This led to Raymond taking an enthusiastic interest in pre-revolutionary Russian postal history, which resulted in numerous publications and awards and, after his retirement, became his main focus of interest.
Risk communication in tables versus text: a registered report randomized trial on ‘fact boxes'
Authors: Brick Cameron , McDowell Michelle , Freeman Alexandra L. J.
Published: March 2020

Objectives: identifying effective summary formats is fundamental to multiple fields including science communication, systematic reviews, evidence-based policy and medical decision-making. This study tested whether table or text-only formats lead to better comprehension of the potential harms and benefits of different options, here in a medical context. Design: pre-registered, longitudinal experiment: between-subjects factorial 2 (message format) × 2 topic (therapeutic or preventative intervention) on comprehension and later recall (CONSORT-SPI 2018). Setting: longitudinal online survey experiment. Participants: 2305 census-matched UK residents recruited through the survey panel firm YouGov. Primary outcome measure: comprehension of harms and benefits and knowledge recall after six weeks. Results: fact boxes—simple tabular messages—led to more comprehension (d= 0.39) and slightly more knowledge recall after six weeks (d= 0.12) compared to the same information in text. These patterns of results were consistent between the two medical topics and across all levels of objective numeracy and education. Fact boxes were rated as more engaging than text, and there were no differences between formats in treatment decisions, feeling informed or trust. Conclusions: the brief table format of the fact box improved the comprehension of harms and benefits relative to the text-only control. Effective communication supports informed consent and decision-making and brings ethical and practical advantages. Fact boxes and other summary formats may be effective in a wide range of communication contexts.
In the face of climate change and exhaustive exercise: the physiological response of an important recreational fish species
Authors: Crear Daniel P. , Brill Rich W. , Averilla Lauren M. L. , Meakem Sara C. , Weng Kevin C.
Published: March 2020

Cobia (Rachycentron canadum) support recreational fisheries along the US mid- and south-Atlantic states and have been recently subjected to increased fishing effort, primarily during their spawning season in coastal habitats where increasing temperatures and expanding hypoxic zones are occurring due to climate change. We therefore undertook a study to quantify the physiological abilities of cobia to withstand increases in temperature and hypoxia, including their ability to recover from exhaustive exercise. Respirometry was conducted on cobia from Chesapeake Bay to determine aerobic scope, critical oxygen saturation, ventilation volume and the time to recover from exhaustive exercise under temperature and oxygen conditions projected to be more common in inshore areas by the middle and end of this century. Cobia physiologically tolerated predicted mid- and end-of-century temperatures (28–32°C) and oxygen concentrations as low as 1.7–2.4 mg l−1. Our results indicated cobia can withstand environmental fluctuations that occur in coastal habitats and the broad environmental conditions their prey items can tolerate. However, at these high temperatures, some cobia did suffer post-exercise mortality. It appears cobia will be able to withstand near-future climate impacts in coastal habitats like Chesapeake Bay, but as conditions worsen, catch-and-release fishing may result in higher mortality than under present conditions.
Structural variation in
Drosophila melanogaster
spermathecal ducts and its association with sperm competition dynamics
Authors: Hopkins Ben R. , Sepil Irem , Wigby Stuart
Published: March 2020

The ability of female insects to retain and use sperm for days, months, or even years after mating requires specialized storage organs in the reproductive tract. In most orders, these organs include a pair of sclerotized capsules known as spermathecae. Here, we report that some
Drosophila melanogaster
females exhibit previously uncharacterized structures within the distal portion of the muscular duct that links a spermatheca to the uterus. We find that these ‘spermathecal duct presences' (SDPs) may form in either or both ducts and can extend from the duct into the sperm-storing capsule itself. We further find that the incidence of SDPs varies significantly between genotypes, but does not change significantly with the age or mating status of females, the latter indicating that SDPs are not composed of or stimulated by sperm or male seminal proteins. We show that SDPs affect neither the number of first male sperm held in a spermatheca nor the number of offspring produced after a single mating. However, we find evidence that SDPs are associated with a lack of second male sperm in the spermathecae after females remate. This raises the possibility that SDPs provide a mechanism for variation in sperm competition outcome among females.
Mutually unbiased bases containing a complex Hadamard matrix of Schmidt rank three
Authors: Hu Mengyao , Chen Lin , Sun Yize
Published: March 2020

Constructing four six-dimensional mutually unbiased bases (MUBs) is an open problem in quantum physics and measurement. We investigate the existence of four MUBs including the identity, and a complex Hadamard matrix (CHM) of Schmidt rank three. The CHM is equivalent to a controlled unitary operation on the qubit-qutrit system via local unitary transformation
I
2
 ⊗ 
V
and
I
2
 ⊗ 
W
. We show that
V
and
W
have no zero entry, and apply it to exclude constructed examples as members of MUBs. We further show that the maximum of entangling power of controlled unitary operation is log
2
3 ebits. We derive the condition under which the maximum is achieved, and construct concrete examples. Our results describe the phenomenon that if a CHM of Schmidt rank three belongs to an MUB then its entangling power may not reach the maximum.
Deep neural networks for waves assisted by the Wiener–Hopf method
Authors: Huang Xun
Published: March 2020

In this work, the classical Wiener–Hopf method is incorporated into the emerging deep neural networks for the study of certain wave problems. The essential idea is to use the first-principle-based analytical method to efficiently produce a large volume of datasets that would supervise the learning of data-hungry deep neural networks, and to further explain the working mechanisms on underneath. To demonstrate such a combinational research strategy, a deep feed-forward network is first used to approximate the forward propagation model of a duct acoustic problem, which can find important aerospace applications in aeroengine noise tests. Next, a convolutional type U-net is developed to learn spatial derivatives in wave equations, which could help to promote computational paradigm in mathematical physics and engineering applications. A couple of extensions of the U-net architecture are proposed to further impose possible physical constraints. Finally, after giving the implementation details, the performance of the neural networks are studied by comparing with analytical solutions from the Wiener–Hopf method. Overall, the Wiener–Hopf method is used here from a totally new perspective and such a combinational research strategy shall represent the key achievement of this work.