bluuebunny/crossref_metadata_2025 huggingface dataset:
Problems and Stages of Legal Science and Education Development in Russia
Authors: Shchankina Liubov Nikolaevna , Izutina Svetlana Viktorovna
Published: June 2020

In the article attention is focused on the study of the problem of the formation of legal science and education in various chronological periods of the existence of the Russian state. State figures, Russian and foreign thinkers, and legal scholars whose contribution to Russian jurisprudence is the most significant are highlighted. It is revealed that the formation and development of theoretical jurisprudence was caused by the needs of society and the state in fair law, as well as the need to systematize the current legislation. The conclusion of the authors is that the formation of legal education in Russia was actively promoted by the state authorities, which contributed to the publication of the first textbooks and manuals on civil and criminal laws; the opening of schools, gymnasiums, and universities. The authors of the article outline that activities of these special educational institutions were of great importance for the formation of the system of legal science and education, on the basis of which there were scientific schools and directions that were developed in the Soviet period and at the present stage. It is mentioned that gradually, the methodological tools were updated and legal education was reformed. After the collapse of the USSR, there were serious changes in it and a kind of Renaissance came. The authors come to the conclusion that currently legal education is designed as an open system that is ready to accept the positive experience of foreign countries and is capable of self-improvement.
Poniatie i soderzhanie gosudarstvennoi politiki RF v oblasti pensionnogo obespecheniia
Authors: Khadykina Elena Viktorovna
Published: June 2020

The modern regulatory consolidation of the foundations of state policy in the field of pension provision is reviewed in the article; the analysis of the legal nature and content of certain areas of state policy in this area is presented.
Analysis of the Status and Prospects of Use of Production and Consumption Waste
Authors: Kostygova Liudmila Aleksandrovna
Published: June 2020

The article is based on the analysis of world experience in the field of modern strategies for recycling, utilization and neutralization of waste and identifies ways to improve these processes. It is established that the main focus is on the use of the principles of the circular economy, areas of its development are highlighted. The creation of a closed economic cycle is particularly important area for the development of circular economy. It allows to achieve a sharp reduction in the consumption of primary raw materials and ensure maximum use of waste. It is noted that particular importance is currently being paid to the issue of household waste recycling. It is pointed out that in Russia, a system of legislative and organizational measures has been developed to solve this problem. The author comes to the conclusion that foreign and domestic experience shows that the implementation of circular economy approaches at the regional and interregional level is most fully implemented in cluster structures.
Use of Virtual Reality as a Distraction Technique to Limit Opiate Use in Traumatic and Surgical Wound Dressing Management
Authors: Chi Albert , Chi Albert , Jockusch Julius , Long Michael , Lund Peter , Sherry Scott
Published: June 2020

Background: Chronic opiate use in traumatic and surgical wound management has become an increasingly
controversial topic nationally. Here we present a case of a large surgical wound previously managed with
operative dressing changes with significant opiate use for pain control with the use of virtual reality at the
time of dressing changes to decrease opiate use as well as operative need; and therefore, overall cost.
Case Presentation: The patient is a 57-year-old female with morbid obesity and poorly controlled diabetes
mellitus who presented with a necrotizing soft tissue infection of the left thigh. She was admitted to the
intensive care unit, initiated on broad spectrum antibiotics, and taken to the operating room for excisional
debridement. After stabilization and source control, the patient continued to require operative incisional
wound vac changes every other day despite maximal multimodal pain therapy. After discussion with the
patient regarding her continued ongoing operative wound vac changes and her desire to progress care, the
team attempted a bedside dressing change utilizing the Facebook Oculus Quest Virtual Reality device
application “Nature Treks VR”. The patient endorsed reduced pain scores during the dressing change and
endorsed emersion into the virtual world throughout the dressing change.
Conclusion: To the best of our knowledge this is the first reported incidence of using a virtual reality
platform to reduce opiate use, operative need, progression of care, and overall cost in a patient with a large,
debilitating operative wound outside of the burn population. Advances in virtual reality hardware including
tether less systems like Oculus Quest, non-controller hand tracking and headset sanitation devices have
reduced barriers to introducing virtual reality therapy into the clinic and ICU. A prospective study is needed
to validate the use of virtual reality as a distraction therapy at the time of dressing changes. Future use of
virtual reality may involve reducing ICU delirium, targeted pain management, post trauma recovery
exercises and enhanced rehabilitation of amputees with prosthetic devices.
Pulmonary Artery Migration of a Peripheral Endovascular Stent Discovered Prior to Renal Transplantation: A Case Report
Authors: Lee Angela , Brubaker Aleah L. , Lee Angela , Perrault David , Melcher Marc L. , Than Peter A.
Published: June 2020

Background: Arteriovenous fistulas and grafts are preferred access for hemodialysis. Outflow stenosis is a
common complication that can be managed with angioplasty and stenting. Stent placement can be
complicated by thrombosis, limited area of cannulation, fracture, and migration.
Objective: This case reports a rare complication of endovascular stents, namely stent migration to the
pulmonary artery in the setting of renal transplantation.
Methods: A 55-year-old woman with end stage renal disease secondary to diabetes mellitus on
hemodialysis via a left arm basilic vein transposition. She subsequently developed outflow stenosis that was
treated with a stent placement. She was admitted for deceased donor kidney transplantation and preoperative
x-ray showed migration of the stent into a segmental pulmonary artery. After a pre-operative,
multidisciplinary discussion between interventional radiology, cardiothoracic surgery, transplant
nephrology and transplant surgery, the decision was made to proceed with rental transplantation followed
by stent removal. Interventional radiology removed the stent on postoperative day two without
complication. She has not experienced any complications in the year following her transplantation.
Conclusion: Postoperative stent removal by interventional radiology is a feasible management option in
lieu of lifelong anticoagulation.
Confluent and Reticulated Papillomatosis of Gougerot and Carteaud in Two Identical Twins: Case Report
Authors: Casali Thaís Gomes , Braga Malveira Maria Isabel , Dornelas Adriana Martins , Gualter Leite Allen Baia , Couri Gamonal Aloisio Carlos , Marques Nogueira Castañon Maria Christina , Silva Marchetti Raquel Quintao e , Lima Gamonal Shirley Braga , Casali Thaís Gomes
Published: June 2020

Confluent and reticulated papillomatosis of Gougerot-Carteaud (CARP) is a rare dermatosis. Even though
many authors affirm that it is a keratinization disorder, the causes are still unknown. There are various
therapeutic options to treat this disorder: retinoids, antibiotics, keratolytic, and others, but the results are
unsatisfactory. This study presents the case of two identical twins, approaching clinic characteristics, as well
as histopathologic characteristics, and the difficulties of finding the correct diagnosis since it is a rare
disease.
The Historical Dynamics of Art Criticism Concepts of the Late 19th through the Early 20th Century in Ukraine
Authors: Наталя Мандра
Published: June 2020

Art criticism concepts dominating in the indicated era were established, examined from the point of view of their significance for the formulation and solution of the main artistic problems of this historical period. The totality of concepts subordinated to the search for “grammar of art”, their relationship with the category of form as an organization of elements, as well as categories of visual and descriptive are defined. The connection between a change in the art criticism methodology and a change in the meaning of concepts in the Ukrainian context was traced.
Postmodernism: Methodological Strategies
Authors: Оксана Мусієнко
Published: June 2020

The article discusses the methodological strategies of the famous postmodern philosophers; determines their dominant directions and the possibilities for their application in artistic practice. The deep transformations of the aesthetic paradigm in the postmodern era provide an integrated approach to certain problems, given the comprehensive pluralism, the rejection of hierarchy in modern cultural discourse. Scientific novelty lies in the wide extrapolation of the methodological foundations of the postmodern way of thinking to analytical approaches towards the contemporary film process. Attention is drawn to the phenomenon of visual citation as an element of intertext. The problem of the Other in the aspect of the mosaic of modern culture is considered. The paradigm shift in the philosophy of postmodernism has an undeniable impact on artistic processes, in particular in cinema, which is manifested in the fundamental transformations of the figurative system of screen arts, their further enrichment and diversity.
Methodological Bases of Conducting a Scientific Research under the Specialty 023 — “The Fine Arts, Decorative Art, Restoration”
Authors: Ольга Школьна
Published: June 2020

Methodological basis of realization of scientific research on art criticism within the new code number 023 is examined in the article. As there is no passport for this specialty yet, despite ongoing postgraduate studies and doctoral studies, many have significant concerns regarding the content of the specialty and methodology of dissertations. Considering specificity of the given problematics, which is caused by three directions for research, specified in the specialty title (fine arts, decorative art, restoration), it is possible to speak about three separate specializations and necessity to develop unified methodological toolkit. Also, art theory and history has not been outlined as a separate specialty (common practice in some Post-Soviet states). Accordingly, additional provisions ofsuch specialty are much needed.
The Art of Carving and Preconditions of Establishment of Spatial and Object Design in Galicia
Authors: Роман Одрехівський
Published: June 2020

The study emphasizes the importance of carving in spatial and object design in Galicia region of Ukraine. It has been proven that one of the factors that influenced the development of carving was the work of a number of original masters, who were inspired by the centuries’ old traditions of folk art: ornamental-compositional structures, scenes of carved decoration, techniques of carving, symbolism of images, religious ritual, etc.Analysis of the most famous iconostases made in the Ukrainian style showed that traditions of the folk religious art (ornaments of the shamrocket, etc.) and archaics (diamond-shaped, circular and other geometric ornaments) served as the basis for their carved decorations. Thus, Ukrainian modernism was the culmination of a long-term evolutionary process that formed the spatial and object design of churches in Galicia
M. Storozhenko’s Monumental Art asa Synthesis of Traditions and Innovations
Authors: Олесь Соловей
Published: June 2020

Мykola Storozhenko is an outstanding Ukrainian artist of the 20th and early 21st centuries, who successfully worked in various genres and types of the art: monumental and decorative painting, mosaics, easel oil painting, easel and book graphic arts, etc. Metaphoric system of M.A. Storozhenko in monumental art is determined by a number of cultural and artistic factors. It is established that the artistic and aesthetic principles of the monumental art of M.A. Storozhenko were formed on the basis of the synthesis of the Byzantine art with the national culture. The innovative methods of the outstanding master were examined and traditional influences on the artistic imagery of the monumental works of M.A. Storozhenko were revealed. It is proved that the search for the appropriate plastic language and experiments with the form were aimed to create a new metaphoric system, based on the synthesis of traditions and innovations
Bayreuth Festival 2019: Tannhäuser Premiere
Authors: Олексій Гончар
Published: June 2020

The new production of Richard Wagner’s opera “Tannhauser”, presented in the program of the Bayreuth Opera Festival in 2019, has been analyzed. The work discusses the use by director Tobias Kratzer of modern techniques ofscenographic and directorial work, which combines traditional theater techniques and new achievements, multi-media and contexts that are associated with the personality of the author and the history of the festival. Personality of the composer and details of his biography were used both in the visual series of the film and brought into the image of the main character of the opera. One of the contexts of using the image of the composer was the replacement of the religious theme of the work with a cult of personality of the author, when the goal of religious pilgrimage instead of Rome is worship of art in Bayreuth. Additional meanings used in the production were the appeal to the characteristic images of German culture, which acquired idiomatic meaning and allusions to the conceptual art of the twentieth century. Such an unconventional approach to the interpretation of the plot has become a new page in the history of the festival productions of “Tannhäuser”.
The Emergence of New Genre Invariants in the Framework of the Festival “Two Days and Two Nights of New Music”
Authors: Асматі Чібалашвілі
Published: June 2020

The active process of transformation of music genres began at the beginning of the twentieth century. The changes were primarily associated with attempts to overcome the traditions of late romanticism at all structural levels of the work. The article discusses the main signs of genre updating and identifies factors that influenced the process of genre modifications: innovative interpretation of traditional genres; combination of different genres; inclusion of elements from other forms of art in the musical work and involvement of new technologies. It is proved that the festival “Two days and two nights of new music”, thanks to its unique format, contributed to the process of emergence of new genre invariants in the works of contemporary composers. Due to its focus on the interaction of various types of art and its unique format with conceptual and dramatic structure, the festival “Two days and two nights of new music” contributes to emergence and development of modern forms of artistic communication and representation of works
Periods of Development of Ukrainian Circus During the Contemporary Era (late 20th through the early 21stcentury)
Authors: Владислав Кашуба
Published: June 2020

The phases of the Ukrainian circus’s organizational and creative development at the post-colonial period are investigated. Four periods of the state circus system formation were detected. The first one is a period of stagnation (the 1980s), which was financially and creatively successful, but restricted national, economic and creative freedoms. All the circuses were strictly accountable to the Soviet Union head circus organization — “Soyuzgostsirk”, an organizational and creative basis of circus system. During the initial period (late 1991 through the early 1993) the circus system’s organizational structure in independent Ukraine was chaotic and dependent on Russia. The dependency decreased at the centralization period (1993–2003), when the Ukrainian circus formed its own artistic conveyor and The Ukrainian State Circus Artistic Association head organization — “Ukrderzhtsirk” (later — State Circus Company of Ukraine). Circus enterprises tended to centralized planning, organization and control of circus product creation and rental. The trend was reversed during the reform period continuing till the present time. State interference into the circus production organizing has furthered decentralization trend. The reform’s appropriateness and consequences steel require further investigation
Transformations of Chinese motifs in the works of François Bouchet and in European Architecture
Authors: Юлія Івашко  , Чан Пен
Published: June 2020

The influence of traditional Chinese architecture and art on European architecture and art of the 17th through early 20th centuries has been analyzed. This hobby turned out to be so massive that it formed a separate style line — chinoiserie, and was primarily manifested in the purchases of Chinese porcelain dishes, vases, screens, accessories, silk fabrics. Subsequently, writers and artists of the Rococo style took up the Chinese theme, because the chinoiserie style is often characterized as a Rococo trend. The heyday of the chinoiserie style falls on the 18th century. The most characteristic example are the works of the French artist François Bouchet, whose paintings express the image of China for Europeans.A comparative analysis of European and Chinese secular plots demonstrates two different approaches to the compositional construction of plots, where Chinese man and women with European appearance are depicted in picturesque poses in Boucher’s paintings, which was unusual for Chinese ceremonial portraits, where the expression of emotions was interpreted as something obscene, characteristic of servants, which is the direct influence of Taoism and Buddhism with their specific attitude to emotions.In architecture, these manifestations were expressed in the appearance of park “oriental-style” structures. European gazebos were a simplified version of the Chinese garden and park pavilions with original silhouettes and curved roofs. Inheriting Chinese traditions, Europe perceived the leash as an external form, while, as traditional Chinese art and architecture, canons were based on philosophical and religious teachings.
Perfil de susceptibilidade antimicrobiana de Staphylococcus spp. associados a mastite bovina
Authors: Moraes Maria
Published: June 2020

The purpose of the present study was isolation and identification of the coagulase-positive Staphylococcus (CoPS) and the coagulase-negative Staphylococcus (CoNS) in cows suspected of having mastites and determine your antimicrobial susceptibility profile. For this 29 samples of Staphylococcus spp. were used. They were collected in two rural properties around the Bragantina (SP) zone and identified through tests such as Gram staining, catalase test, seeded agar plates, Manitol salt agar test and the coagulase test. The samples were classified as coagulase- positive Staphylococcus (34,48%) and coagulase-negative Staphylococcus (65,52%). The antibiogram was performed using the Kirby-Bauer disk diffusion technique. The highest percentage of resistant samples occurred with Penicillin (34,48%), followed by Oxaciline (20,69%) and Erythromycin (17,24%). More sensibility to the following antimicrobials was observed: Gentamicin (96,55%), Tetracycline (87,76%). The misuse and overuse can cause a bigger amount of bacteria resistant to the antimicrobials. Therefore, the microbiological culture and the antibiogram are techniques that ought to be used to establish a correct diagnosis of mastitis, thus helping with the choice of the treatment. The hygiene-sanitary management and prevention to bovine mastitis need to be considered important to assist with the reduction of the use of antimicrobials on dairy cattle, which can be reached through educational programs and actions and also through agricultural extension.
Neoplasias mamárias em cadelas: um estudo estatístico para auxiliar no tratamento
Authors: Chagas Jônathan , Gonçalves Regiane , Leonor Alba , Crespilho André , Roier Erica , Gomes Suzana , Ferreira Renata
Published: June 2020

With the increase in life expectancy of domestic animals and their relationship with the increasingly affective guardians, it is possible to observe an increase in cases of neoplasms in these animals. Mammary neoplasia mainly affects the elderly and non-castrated females due to hormonal dependence for tumor development. The main means of treatment for this cancer is surgical removal of the affected breast or mammary chain. This study aimed to evaluate the characteristics of breast neoplasms and to relate them to other variables, such as age, tumor margin and lymph node metastasis to try to direct the choice of the surgical technique to be used in the treatment. Through statistical analysis of the reports, it was possible to state that there is a relationship between tumor longevity and malignancy, and this increases the chances of lymph node metastases and surgical margins, thanks to the expansion capacity of the malignant neoplasm. A higher number of animals with a defined breed was found, compared to animals without a defined breed, and this data may also be related to the emergence of mammary neoplasms. Therefore, it can be concluded that long-lived female dogs should undergo radical mastectomy due to the degree of invasiveness of malignant neoplasms, a characteristic presented in this study group.
Fibrossarcoma em cão Rottweiler: relato de caso
Authors: Carneiro Milena , Yelimar Palmero Quintana Celia , Carvalho Andrade Ingrid , Zago Lupepsa Beatriz , Abreu Campos da Cruz Pollyana , Teixeira da Silva Fonseca Larissa , Nascimento Pires Greice
Published: June 2020

The present study aims to report a case of fibrosarcoma in an elderly canine patient who underwent necroscopic examination in June 2018 after natural death. Macroscopic and microscopic analyzes of the pathological findings were performed by organ visualization and histopathological processing of the collected samples. Macroscopically, a pelvic tumor mass of approximately 15 cm, cardiac hypertrophy with parasites in the ventricular lumen, congested and nodular lungs, hepatomegaly and renal atrophy were observed. Histological analysis of the primary tumor mass was compatible with a fibrosarcoma, with most cells of fusiform morphology, with foci of hemorrhage and necrosis in the center of the tumor, alternating with regions of desmoplastic reaction, nuclear atypia and prominent nucleoli. Also, microscopy revealed swollen pulmonary parenchyma with diffuse hemorrhage, vascular congestion, thickening of the alveolar septa and pulmonary nodules suggestive of metastatic lesions, as well as liver with congested sinus capillaries and diffuse hemorrhage in the hepatic parenchyma with foci of coagulation necrosis. Fibrosarcoma is a tumor of mesenchymal origin, composed of transformed fibroblasts, in a collagen background. It occurs in all species, but is more common in dogs and cats. In dogs, it usually manifests in solitary form and in older individuals, with a mean age of 9.7 years. Most pathologists describe the histological picture of fibrosarcoma as a fishbone pattern. It is usually a very invasive tumor, making surgical treatment difficult because it does not allow a wide margin of excision, and its clinic manifests itself late, making diagnosis and treatment even more difficult, as in the case reported here, in which the patient suddenly died. Thus, histopathological and cytopathological analysis remain the gold standard among the initial diagnostic methods to confirm the presence of the tumor, highlighting the importance of applying these study methods in determining the morphological characteristics of different types of lesions, as well as their forms, whose diagnosis can be confirmed with other diagnostic methods.
Gestão na suinocultura: um conceito holístico
Authors: Castro Lívia , Maria dos Reis Barbosa Lívia , Da Silva de Vasconcelos Bruno
Published: June 2020

In the technical swine industry, information management should play a central role in decision-making, involving careful management methods, accurate monitoring of information, implementation of corrections and people management. Given this, production planning, goal setting and action plan are starting points in management. Therefore, the proper management of pig activity requires data collection, to transform into information, in order to define the objectives, potentialities with available resources. This review aimed to address the best practices in pig production management with a view to business sustainability, improvement of productive efficiency and profitability, emphasizing important concepts and their practical applications.
Avaliação das pressões arterial média femoral e auricular no transoperatório de cães submetidos a neurocirurgias
Authors: Herculano Lícia Flávia , Pasini Jéssika Schopf , Galindo Victor Reis , Soares André Vasconcelos , Mazzanti Alexandre
Published: June 2020

The monitoring of cardiorespiratory function is extremely important for the anesthetized patient, assigning great importance to the monitoring of blood pressure. The mean arterial pressure represents the conduction of the tissue perfusion, thus it is fundamental to measure to ensure a safe anesthesia. Neurological patients are highly susceptible to hemodynamic changes during surgical procedures such as hemilaminectomy and with this, this work has collected information from anesthetic files of patients who underwent this surgery at the Federal University of Santa Maria from January 2016 to October 2017. This study aims to evaluate retrospectively if there is a difference in the mean values between atrial and femoral mean arterial pressure, in order to indicate which is the best alternative for arterial monitoring in patients submitted to hemilaminectomy. It was concluded that there is a statistically significant difference between femoral and auricular blood pressure values.
Leite Ultra Fresh
Authors: Pessine Novaes de lima Bruna
Published: June 2020

The milk has a balanced nutritional composition that includes all the nutrients essential for the growth and development of mammalian species. But there is a great diversity of microorganisms, including pathogens, then its form of industrialization requires specific care. These care needs technical support from the beginning of its production, still in the corral, until reaching the large industries. However, as it is known, milk composes a variability of microorganisms, it is up to the industrialization process to make it suitable for human consumption, so that way dairy products have the option of raising the temperature so that it occurs destruction of present pathogens. The industry with its evolution process has created several methods to perform these pathogen neutralization processes and the objective of this work is to highlight the ultra-high temperature (UHT) technique, which consists of raising the heat intensely for a short period of time.
Suspeita de carcinoma de células escamosas de terceira pálpebra em vaca holandesa: relato de caso
Authors: Ulsenheimer Bruna , Picinin Camila Naiara Batista , Ziegler Simoní Janaína , Shiffer Jorge Luis de Lima , Pereira Roberta Carneiro da Fontoura
Published: June 2020

Abstract. In cattle, squamous cell carcinomas (SCC) are the most frequent malignant tumors. Where the animals most affected are those that have depigmentation in the mucocutaneous region. This study aimed to report the clinical case of suspected third eyelid squamous cell carcinoma in a Holstein cow. Clinical care was carried out on a female bovine, of the Dutch breed of approximately 5 years of age, in the anamnesis, the owner reported that six months ago there had been an increase in volume on the side of the animal's left eye. Upon general clinical examination, no changes in physiological parameters were detected. On specific eye examination, it was found in the left eye that the third eyelid had a bulky mass, with mucopurulent secretion. The treatment performed in this service was through surgery to remove this eye mass, suspected of squamous cell carcinoma. Where the tumor was removed with the maximum safety margin possible so that it would not return again. After topically applied to the affected eye, antibiotic and associated anti-inflammatory, Terra-Cortril® Spray (oxytetracycline hydrochloride and hydrocortisone), for 7 days / BID. In this case, the suspicion of SCC in the third eyelid is concluded through anamnesis and macroscopic lesions visualized on clinical examination. The treatment was surgical excision, but histopathological analysis was not performed, being of total importance for obtaining a conclusive diagnosis. Thus, it is concluded that the follow-up of the case after treatment is extremely important, due to the assessment of the clinical condition.
Bursa Hanlarında Mescidler
Authors: GÜLER Semra
Published: June 2020

Osmanlı Devleti’nin ilk başkenti ve bir ticaret merkezi olarak Bursa’nın en dikkat çekici mimari eserlerinden biri de hanlarıdır. Anadolu Türk mimarisindeki ilk şehir hanı olarak kabul edilen Emir Han’la başlayan imar faaliyetleri, zaman içinde Bursa’nın ticaret hayatının ihtiyaçlarına binaen daha da artmıştır. “Bursa Hanlar Bölgesi” olarak anılan bu bölgedeki hanlar, akademik olarak daha çok ticarî ve mimari yönleriyle bütünsel olarak ele alınmış, hanlardaki mescidler hakkında yeterli değerlendirme yapılmadığı tespit edilmiştir. Günümüzde hala mevcud olan Koza Han, Fidan Han ve Geyve Han’daki mescidlerden Koza Han ile Fidan Han’dakiler köşk mescid olarak tasarlanmışken, Geyve Han’daki ise hanın zemin katında bir oda biçimindedir. Ayrıca kaynaklarda Kapan Han, İpek Han, Pirinç Han ve Eski Yeni Han’ın da mescidleri olduğu bilgisi mevcuttur. Bursa Hanlarındaki mescidlerin, Selçuklu kervansaraylarında başlayan köşk mescid geleneğinin bir devamı olduğu söylenebilir ancak plan bakımından daha farklı oldukları anlaşılmaktadır. Bu makale, Bursa hanlarındaki mescidlerin Osmanlı Mimarisindeki yeri ve önemini ortaya koyma gayretindedir.
Behavior of “arvalis” and “obscurus” chromosomal forms of common vole males in the forced swim test
Authors: Sablina S.A. , Belozertseva I.V.
Published: June 2020

To determine the difference in stress response between two chromosomal forms of a common vole, the “arvalis” and “obscurus”, the behavior of adult (6–12 months) lab-born vole males were evaluated in a forced swim test. During the test, they were carefully placed into glass cylinders (d=12 cm, h=20 cm) filled with water (h=15 cm, 24±1°C) and remained there for up to 6 min. Their behavioral patterns were video recorded and continuously monitored (Ethograph, ver. 2.7, RITEC, Russia) to document the duration of swimming and paddling (orientation), floating (immobility) and climbing (escape). Two series of experiments were performed, in May 2016 and June 2017, with independent groups: “arvalis” (N=9 each year) and “obscurus” (N=9 and 22 each year, respectively). The «arvalis» and «obscurus» significantly differed in their responses to the stress test. Over 35% of obscurus males (2 of 9 in 2016 and 9 of 22 in 2017) failed to complete the test, within 3 min these animals had to be rescued to prevent drowning (significant differences from “arvalis” according to Fisher's exact test). “Arvalis” voles displayed higher duration of escape attempts (F(1.14)=3.5; P=0.08 – for first; F(1.20)=15.6; P<0.001 – for second series of experiment), shorter duration of swimming and paddling (significantly in the first series – F(1.14)=14.3; P<0.005), and shorter duration of immobility (significantly in the second series – (F(1.20)=6.1; P<0.001). The results suggest that two chromosomal forms of common vole have major differences in stress response behavior. In the forced swim test, the “arvalis” voles are displaying higher endurance, associated with active escape behavior, when compared to “obscurus” animals. Further studies need to address their responses to other stress paradigms and to water environment, in general. The latter may play a major role in vole migration when they meet water barriers in their natural environment.
Results of annual honey bee colony losses survey in Ukraine: winter 2017-2018
Authors: Fedoriak M , Tymochko L , Kulmanov O , Shkrobanets O , Zhuk A , Dron Y , Deli O , Podobivskiy S , Melnychenko G , Leheta U , Kholivchuk A
Published: June 2020

Decline of honey bee colonies remains a global problem. It may affect catastrophically both ecosystems and the global economy. Here we present the results of the fourth year of a research project on bee colony losses in Ukraine over winter 2017-2018, conducted in the framework of international monitoring coordinated by the non-profit honey bee research association COLOSS. Overall winter loss rate and the mortality rate over winter 2017-2018 were significantly lower compared to the previous year: overall winter loss rate – 11.3% (95 % СІ 10.0-12.6); mortality rate – 6.7% (95 % СІ 5.8-7.7); rate of colony loss due to unsolvable queen problems – 2.1% (95 % СІ 1.6-2.7) and due to natural disasters – 2.4% (95 % СІ 2.0-3.0). Likewise previous years, the highest losses were observed in small operations (with 50 or fewer colonies). The highest overall loss rate was observed in the Steppe zone, with the highest both mortality rate and losses due to natural disasters compared to the other physiographic zones of Ukraine. Minimum mortality was recorded from deciduous forests 5.6 % (95 % CI 4.4-7.2) and the Ukrainian Carpathians 5.5 % (95 % CI 4.2-7.2). Winter losses related to queen problems varied greatly with a minimum in the Forest-Steppe zone 0.71 % (95 % CI 0.3-1.5). 83.3% of beekeepers treated their colonies against Varroa. The r-rank correlation analysis identified two potential risk factors (no or only a few dead bees in or in front of the empty hive; dead workers in cells and no food present) which revealed a weak positive correlation with both mortality rate and the rate of losses due to unsolvable queen problems.
Portulaca cypria Danin, P. granulatostellulata (Poelln.) Ricceri & Arrigoni, P. papillatostellulata (Danin & H. G. Baker) Danin (Portulacaceae Juss.) – new for the Ukrainian flora taxa from the territory of Transcarpathia
Authors: Bulakh O , Protopopova V , Shevera M
Published: June 2020

The results of studying of seeds of the Portulaca oleracea L. (Portulacaceae Juss.) from Transcarpathia (Ukraine) are presented in the publication. The seed surface ultrastructure of taxa of the P. oleracea-aggr. based on the results of micromorphological studies with using electronic scanning microscope was described. The general for the representative of the genus (e.g. globous, ovate or almost reniform shaped of seeds; dark) and specify for the morphological types (star-shaped, isodiametric or elongate cells of seed surface with central part and long or short rays; smooth surface of seed or with knobs (from 0,03 mm in diameter) or papillae (0,01–0,02 mm in diameter), etc.) peculiarity are determined. The original figures of seed surface ultrastructure of the studied morphological types and key for its determination are prepared. As a results of investigation the new for the Ukrainian flora taxa, P. cypria Danin, P. granulatostellulata (Poelln.) Ricceri & Arrigoni and P. papillatostellulata (Danin & H.G. Baker) Danin, from Transcarpathia are presented. All studied species are: kenophytes according time of immigration; xenophytes, according way of distribution; and ephemerophytes, according degree of naturalization. The map of distribution of the taxa in the region is presented.
Syntaxonomic scheme of grassy vegetation of the upper Prut and Siret river basins
Authors: Budzhak Vasyl'
Published: June 2020

This is the first time that ecological-floristic classification scheme of grassy vegetation of the upper Prut and Siret basins within Ukraine was set up based on the analysis of field research and literature resources. The foundations for syntaxonomic scheme of vegetation was database of geobotanical descriptions «Vegetation of Bukovina», which was created on the Department of botany, forestry, garden and park management in the shell of TURBOVEG. This database contains more than 5000 geobotanical descriptions made in accordance with standardized approach. There was used cluster analysis based on modified TWINSPAN algorithm in JUICE shell for allocation of vegetation units. Syntaxonomic scheme of grassy vegetation of the researched area includes 9 classes, 21 orders, 33 alliances.
Analyse and rule? A conceptual framework for explaining the variable appeals of ex-ante evaluation in policymaking
Authors: Paul Regine
Published: June 2020

This article integrates disparate explanations for increasing (but variable) turns to ex-ante policy evaluation, such as risk analysis, across public administrations. So far unconnected silos of literature – on policy tools, policy instrumentation, the politics of evaluation and the political sociology of quantification – inconsistently portray ex-ante evaluation as rational problem-solving, symbolic actions of institutional self-defence, or (less often) political power-seeking. I synthesise these explanations in an interpretivist and institutionalist reading of ex-ante evaluation as contextually filtered process of selective meaning-making. From this methodological umbrella emerges my unified typology of ex-ante evaluation as instrumental problemsolving (I), legitimacy-seeking (L) and powerseeking (P). I argue that a) these ideal-types coexist in policymakers’ reasoning about the expected merits of ex-ante evaluation, whilst b) diverse institutional contexts will favour variable weightings of I, L and P in policymaking. By means of systematisation the typology seeks to inspire an interdisciplinary research agenda on varieties of ex-ante evaluation.
Low and high energy solutions of oscillatory non-autonomous Schrödinger equations with magnetic field
Authors: Zhang Youpei , Tang Xianhua
Published: June 2020

We are concerned with the mathematical and asymptotic analysis of solutions to the following nonlinear problem [Formula: see text] where [Formula: see text] is the magnetic Laplace operator, [Formula: see text] is a smooth bounded domain, [Formula: see text] is the magnetic potential, [Formula: see text], λ is a real parameter, [Formula: see text] is an indefinite potential, q is nonnegative, and [Formula: see text] is a reaction that oscillates either in a neighborhood of the origin or at infinity. We analyze two distinct cases, in close relationship with the oscillatory growth of the reaction. Additionally, we give asymptotic estimates for the norm of the solutions in related function spaces.
Plasma Neurofilament Light: A Marker of Neurodegeneration in Mild Behavioral Impairment
Authors: Naude James P. , Gill Sascha , Hu Sophie , McGirr Alexander , Forkert Nils D. , Monchi Oury , Stys Peter K. , Smith Eric E. , Ismail Zahinoor ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2020

Background:

Assessing neuropsychiatric symptoms (NPS) in older adults is important for determining dementia risk. Mild behavioral impairment (MBI) is an at-risk state for cognitive decline and dementia, characterized by emergent NPS in later life. MBI has significantly higher dementia incidence than late life psychiatric conditions. However, its utility as a proxy for neurodegeneration has not been demonstrated. Plasma neurofilament light (NfL) is a validated biomarker of axonal damage, and has been shown to associate with hallmarks of neurodegeneration.

Objective:

The purpose of this investigation was to identify associations between NfL rate of change and the presence of MBI symptomatology.

Methods:

We evaluated the association of MBI with changes in NfL in a cohort ( n = 584; MBI + n = 190, MBI– n = 394) of non-demented participants from the Alzheimer’s Disease Neuroimaging Initiative. MBI was determined by transforming Neuropsychiatric Inventory Questionnaire items using a published algorithm. Change in NfL was calculated over 2 years.

Results:

Time*MBI status was the only significant interaction to predict change in NfL concentrations ( F(1,574) = 4.59, p = 0.032), even after controlling for age, mild cognitive impairment, and demographics. Analyses reclassifying 64 participants with new onset MBI over 2 years similarly demonstrated greater increases in NfL ( F(1,574) = 5.82, p = 0.016).

Conclusion:

These findings suggest MBI is a clinical proxy of early phase neurodegeneration with putative utility in identifying those at dementia risk. MBI can be used as a case ascertainment approach to capture those at high risk for cognitive decline and dementia, and is an important construct for clinicians dealing with cognitive and neuropsychiatric symptomatology in older adults.
Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort
Authors: Muurling Marijn , Rhodius-Meester Hanneke F.M. , Pärkkä Juha , van Gils Mark , Frederiksen Kristian S. , Bruun Marie , Hasselbalch Steen G. , Soininen Hilkka , Herukka Sanna-Kaisa , Hallikainen Merja , Teunissen Charlotte E. , Visser Pieter Jelle , Scheltens Philip , van der Flier Wiesje M. , Mattila Jussi , Lötjönen Jyrki , de Boer Casper
Published: June 2020

Background:

Gait analysis with accelerometers is a relatively inexpensive and easy to use method to potentially support clinical diagnoses of Alzheimer’s disease and other dementias. It is not clear, however, which gait features are most informative and how these measures relate to Alzheimer’s disease pathology.

Objective:

In this study, we tested if calculated features of gait 1) differ between cognitively normal subjects (CN), mild cognitive impairment (MCI) patients, and dementia patients, 2) are correlated with cerebrospinal fluid (CSF) biomarkers related to Alzheimer’s disease, and 3) predict cognitive decline.

Methods:

Gait was measured using tri-axial accelerometers attached to the fifth lumbar vertebra (L5) in 58 CN, 58 MCI, and 26 dementia participants, while performing a walk and dual task. Ten gait features were calculated from the vertical L5 accelerations, following principal component analysis clustered in four domains, namely pace, rhythm, time variability, and length variability. Cognitive decline over time was measured using MMSE, and CSF biomarkers were available in a sub-group.

Results:

Linear mixed models showed that dementia patients had lower pace scores than MCI patients and CN subjects ( p < 0.05). In addition, we found associations between the rhythm domain and CSF-tau, especially in the dual task. Gait was not associated with CSF Aβ42 levels and cognitive decline over time as measured with the MMSE.

Conclusion:

These findings suggest that gait — particularly measures related to pace and rhythm — are altered in dementia and have a direct link with measures of neurodegeneration.
Social network visual simulation for process reengineering of construction change management under building information modelling technology
Authors: Zhang Yinglong , Hu Hao , Xu Feng
Published: June 2020

Construction change management is an important part of construction project management. Previous studies usually focus on the various steps of construction change control: analyzing the causes of change, avoiding the risk of change, tracking the process of change, management and feedback of change. This study focused on improving the information flow and organizational relationship of the participants in the process of construction change management, which was reengineered with the use of Building Information Modelling (BIM) technology for better information integration. As BIM technology provides technical means for information transaction and management, a reengineered construction change management process based on BIM technology was proposed to form a more effective way of putting forward, examine, issuing, updating and archiving the information. Both the workflow and the organizational units involved in each work step were reengineered to improve the information flow. To verify the effect of process reengineering, Uncinet, a visual analysis tool for Social network analysis (SNA) was applied to quantitatively analyze and compare the traditional and BIM based organizational structure. The research results demonstrated that BIM was helpful to strengthen organizational coordination and information exchange in construction change management process.
Numerical simulation of three dimensional flow in Yazidang Reservoir based on image processing
Authors: Huang Lingxiao , Qiao Qiao , Zheng Lanxiang , Liu Libo , Zhao Wenjuan , Jing Hefang , Li Chunguang
Published: June 2020

In order to study the water flow movement of the Yazidang Reservoir, this paper generates the initial terrain for the researched water area with the image stitching technology and image edge detection technology, establishes a 3D k - ɛ mathematical model, solves the equations discretely by FVM and SIMPLEC algorithms, studies the numerical simulation of the water flow movement of the reservoir under four working conditions, and analyzes the flow field on the surface and at the bottom of the reservoir. The results show the improved terrain pre-processing accuracy and efficiency of the researched water area and the rationality of the water flow field and rate simulation results, which means that the established 3D turbulence mathematical model can be applied to the numerical simulation of the reservoirs similar to the Yazidang Reservoir. The numerical simulation of 3D turbulence in Yazidang Reservoir provides a theoretical basis and practical application value for the numerical simulation of similar reservoirs.
Cellular cholesterol prediction of mammalian ATP-binding cassette (ABC) proteins based on fuzzy c-means with support vector machine algorithms
Authors: Tripathy Ramamani , Nayak Rudra Kalyan , Das Priti , Mishra Debahuti
Published: June 2020

Over the years protein interaction and prediction of membrane protein have been a pivotal research area for all researchers. For both prokaryotes and eukaryotes Adenosine Triphosphate-(ATP) binding cassette (ABC) genes plays a significant role. In our analysis, we concentrate on human part of ABC genes. In case of living organisms transport of precise molecules across lipid membranes has been treated as vital part and for that reason a bigger transporter is required to carry out the molecules. Here ABC transporter families are evolved to transport the specific molecules such as sugars, amino acid, peptides, proteins, ions etc. within the plasma membrane. As we know another important component of human being is cholesterol, which is a major component in cell membrane and its main functions are to maintain integrity and mechanical stability. Each and every time, membrane cholesterolsareinteracted with membrane protein in both N-C terminuses and target valid sequence(s) which has relevance in human diseases. In this manuscript we have applied Fuzzy C-Means (FCM) with Support Vector Machine (SVM) algorithm for prediction of cellular cholesterol with ABC genes. Our experiments have been performed well using ABCdata set.