bluuebunny/crossref_metadata_2025 huggingface dataset:
Cartografías literarias: anotaciones a propósito de la novela de migración mexicana
Authors: Reyes Zaga Héctor A.
Published: January 2019

Este artículo examina la representación de la experiencia migratoria de mexicanos en los Estados Unidos en la novela mexicana del siglo XX y XXI. Como primera parte se plantea una exploración crítica de los aspectos formales, estructurales y temáticos de la llamada literatura de migración, para después elaborar un mapa de la producción novelística mexicana de temática migratoria basado no sólo en la temporalidad literaria, sino en la interrelación que las obras guardan con los diversosmomentos históricos de la migración mexicana.
Investigación cualitativa: Método fenomenológico hermenéutico
Authors: Fuster Guillen Doris Elida
Published: January 2019

Este artículo presenta nociones fundamentales de uno de los métodos de investigación cualitativa, nos referimos a la fenomenología hermenéutica sustentada en las teorías de Van Manen, Raquel Ayala y Miguel Martínez. Este enfoque conduce a la descripción e interpretación de la esencia de las experiencias vividas, reconoconoce el significado y la importacia en la pedagogía, psicología y sociología según la experiencia recogida. Este método constituye procesos rigurosos y coherentes de las dimensiones éticas de la experiencia cotidiana, difícilmente accesibles por otros métodos usuales de investigación. En esta contribución, se presenta algunas nociones metodológicas centradas en los principios de la fenomenología y sus fases: etapa previa o clarificación de presupuestos, recoger la experiencia vivida, reflexionar acerca de la experiencia vivida o etapa estructural y, finalmente, escribir-reflexionar acerca de la experiencia vivida evidenciada en fisonomía individual y grupal o llamada también texto fenomenológico.
Increase in the constrictor effects of Rho-kinase in skeletal muscle and coronary arteries of rats with chronic hypothyroidism
Authors: Gaynullina D. K. , Selivanova E. K. , Sharova A. P. , Tarasova O. S.
Published: January 2019

Aim. The deficit of thyroid function is known to be accompanied by an increase in the overall peripheral vascular resistance. This work tested the hypothesis that long-term hypothyroidism leads to an increase in the vasoconstrictor effect of Rho-kinase in skeletal muscle and heart resistance arteries of adult rats.

Materials and methods.Male Wistar rats consumed the antithyroid drug propylthiouracil (PTU) in drinking water (0.025%), starting at 10 weeks of age. The rats of the control group received PTU-free water. After 14 weeks, the contractile responses of the gastrocnemius muscle arteries (to the α1-adrenoceptor agonist methoxamine) and the septal coronary artery (to the thromboxane A2 receptor agonist U46619) were isometrically recorded. The contribution of the Rho-kinase to the arterial contractile responses was assessed using inhibitor Y27632 (3 μM).

Results.The consumption of propylthiouracil was accompanied by a marked decrease of thyroid hormone concentrations and an increase in total cholesterol serum level as well as a decrease in body weight. Maximal contractile responses of studied arteries were also reduced in hypothyroid rats. However, basal tone and reactivity to the moderate concentrations of agonists in arteries of hypothyroid rats were increased compared to control animals. Y27632 significantly weakened the contractile responses of the arteries and negated the differences between the two groups of rats.

Conclusion.Chronic hypothyroidism leads to an increase in the activity of the Rho-kinase signaling pathway in the arteries of the gastrocnemius muscle and heart, which results in the increase of the spontaneous tone of the arteries and their reactivity to agonists.
The Impact of a Hospital-Based Awareness Program on the Knowledge of Patients About Breast Cancer and Cancer Cervix
Authors: Elsayed Atwa Azza Mohamed , Hassan Hanan Elzeblawy , Ahmed Safaa Ibrahim
Published: January 2019

Background: Breast cancer and cancer cervix contribute to high morbidity and mortality rates among women worldwide. Appropriate knowledge of both cancers can help in early detection and management. Aim: This study aimed to assess the effect of a hospital-based awareness program on the knowledge of patients attending some outpatient clinics in Sohag University Hospital regarding the 2 cancers. Subjects and Methods: The program was held in Sohag University Hospital on 150 female patients during the period between August and October 2018. The knowledge of the patients about the risk factors, symptoms, screening, and management of both cancers was first assessed using an interview questionnaire. Then, the awareness program included 4 sessions and every session discussed only 1 aspect of knowledge regarding both cancers. Later, patients were assessed again using the same questionnaire and the improvement was determined. Results: The mean age of the participating patients was 29.6 ± 6.7 years, 74.7% could read and write, and 85.3% were married. Only education was associated with better knowledge about breast cancer (p = 0.002) and cancer cervix (p = 0.007). Thanks to the program, the percent of patients with optimal knowledge of breast cancer improved from 14.7% to 50% (p < 0.001). This percent distributed as follows; risk factors 10% to 50% (p < 0.001), manifestations 20% to 60% (p < 0.001), screening 4% to 7% (р < 0.001), and management 24.8% to 63% (p < 0.001). Regarding cancer cervix, the improvement was as follows; total knowledge 13.3% to 46.2% (p < 0.001), risk factors 8% to 50% (p < 0.001), manifestations 12.2% to 50% (р < 0.001), screening 15% to 40% (р < 0.001), and management 18.2% to 44.8% (р < 0.001). Conclusion and Recommendations: Patients had suboptimal knowledge about breast cancer and cancer cervix. However, the program achieved remarkable successes in improving the knowledge of patients. Future programs on a wider scale and different populations should be considered.
An Update on Plant-Derived Compounds as Potential Inhibitors of the Bacterial Efflux Pumps: With Reference to Staphylococcus aureus and Escherichia coli
Authors: Das Saurav , Kumar Santosh , Bhagowati Pabitra , Singh Ashish Kumar
Published: January 2019

Bacterial antibiotic resistance has become a major global health concern. One of the main reasons for the development of multi-drug resistance properties in bacteria is due to the bacterial efflux pump systems. They are important transport proteins, mainly involved in the removal of toxic substrates like antibiotics from inner cell environment. These pumps are responsible for the intrinsic ability of bacteria to get resistant to the antibiotic. Various types of efflux pumps are present in the Gram-positive and Gram-negative bacteria. Plant-derived products like Capsaicin, Olympicin A, and Indirubicin were found to be inhibitors of an efflux pump in Staphylococcus aureus similarly Ursolic acid derivatives; Daidzein and Lanatoside C were plant-derived inhibitors of an efflux pump in Escherichia coli. In this review detail information have been provided about efflux pump inhibitors that have been found to be effective in the Gram-positive bacteria and Gram-negative bacteria. The aim of this review is to focus on the role of plant-derived compounds as effective efflux pumps inhibitors with reference to mainly Staphylococcus aureus and Escherichia coli.
Angiotensin Converting Enzyme Inhibitors and the Risk of Lung Cancer – New Scientific Evidences or Another Example of “Pseudo-Evidence” Medicine?
Authors: Martsevich S. Yu.
Published: January 2019

The quality of the database analysis that led to the conclusion that angiotensin converting enzyme inhibitors contribute to the development of lung cancer is analyzed. The author notes that the analysis of the potential risk from taking these drugs is possible only if it is related to the proven positive effect of these drugs on the prognosis of life in certain categories of patients, primarily with chronic heart failure and a history of acute myocardial infarction. Attention is drawn to the methodological errors of the study, putting the main conclusion of the analysis into question.
The Role of PCSK9 Inhibitors in the Improvement of Outcomes in Patients after Acute Coronary Syndrome: Results of ODYSSEY OUTCOMES Trial
Authors: Karpov Yu. A.
Published: January 2019

The aim of this review was to present the recently published results of ODYSSEY OUTCOMES trial and discuss the clinical perspective of these data. Patients with acute coronary syndrome are at very high risk of recurrent ischemic cardiovascular complications, especially during the first year after the event. The use of high-intensity statin therapy in this group of patients does not always lead to the achievement of target levels of atherogenic lipoproteins. PCSK9 inhibitors, administered in addition to statins, can provide additional reduction of low-density lipoprotein cholesterol, which leads to further improvements of outcomes in patients with atherosclerotic cardiovascular disease. According to the latest results from ODYSSEY OUTCOMES trial, among patients with recent acute coronary syndrome, who were receiving high-intensity statin therapy, the risk of recurrent ischemic cardiovascular events was lower among those who were treated with alirocumab then among those who received placebo. The treatment with alirocumab in patients with recent acute coronary syndrome was associated with reduction in death from any causes. The absolute risk reduction with alirocumab was the most prominent in the subpopulation of patients with low-density lipoprotein cholesterol ≥2,6 mmol/l at baseline. These results have implication for clinical practice and may play an important role for the improvement of outcomes in patients at highest cardiovascular risk after acute cardiovascular syndrome.
P2Y12 Receptor Inhibitors in the Treatment of Patients with Acute Coronary Syndrome and Percutaneous Coronary Intervention: Possibilities of Prasugrel
Authors: Vorobyeva N. M.
Published: January 2019

The possibilities of P2Y12 receptor inhibitors application in the treatment of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) are discussed in the article. The results of 4 registries in which a comparative analysis of the efficacy and safety of prasugrel with clopidogrel or ticagrelor was performed, as well as of all 3 P2Y12-receptor inhibitors among themselves, are considered in detail. The feasibility of replacing clopidogrel to prasugrel during the inpatient treatment of patients with ACS and PCI was evaluated additionally in the MULTIPRAC registry. The results of the registries demonstrate that the use of prasugrel in patients with ACS and PCI is associated with a significant reduction in the risk of ischemic complications and mortality with an acceptable risk of bleeding. At the same time, prasugrel was more effective and safer than clopidogrel and at least was non-inferior to ticagrelor, and according to some registries, even surpasses it in a number of indicators.
Specific Antidotes for Direct Oral Anticoagulants in Life-Threatening Bleeding
Authors: Sumarokov A. B. , Buryachkovskaya L. I. , Lomakin N. V.
Published: January 2019

Review presents data on medicines from the new group of cardiovascular drugs, direct oral anticoagulants (DOACs) inhibitors, as antidotes for DOAC when stopping life-threatening bleeding. DOAC therapy is accorded by hemorrhages with lower frequency than therapy by indirect anticoagulants, but really exist. New antidotes for DOACs are idarucizumab, andexanet, ciraparantag. The need in antidotes for DOAC may suddenly appear in spontaneous bleeding, during surgical operation, invasive procedure, due to trauma, in patients with stroke, kidney or liver failure. Data is given on the frequency of the main types of bleeding while taking new oral anticoagulants. Information concerning use of antidotes for DOACs in bleedings as well as use of non-specific therapy are reviewed.
A Review of the Addition of Cognitive Behavioral Therapy to Physical Rehabilitation for Chronic Nonspecific Low Back Pain
Authors: Sequin Elizabeth , Joseph Jennifer , Cowen Virginia S.
Published: January 2019

Background:

Chronic nonspecific low back pain is common in adults in the United States. The assessment of nonpharmacologic treatment approaches is important in order to refer patients for optimal treatment. The addition of cognitive behavioral therapy (CBT) to physical rehabilitation may improve outcomes.

Methods:

We performed a review of randomized controlled trials comparing physical rehabilitation plus CBT with physical rehabilitation alone.

Results:

Six studies met the inclusion criteria; improvements were noted for all in both groups. Statistically significant differences between the groups were found in only 3 studies.

Conclusions:

The findings were not robust, but they suggest that the addition of CBT may be beneficial as an adjuvant therapy.
Post-Combustion Carbon Dioxide Enhanced-Oil-Recovery Development in a Mature Oil Field: Model Calibration Using a Hierarchical Approach
Authors: Olalotiti-Lawal Feyi , Onishi Tsubasa , Kim Hyunmin , Datta-Gupta Akhil , Fujita Yusuke , Hagiwara Kenji
Published: January 2019

We present a simulation study of a mature reservoir for carbon dioxide (CO2) enhanced-oil-recovery (EOR) development. This project is currently recognized as the world's largest project using post-combustion CO2 from power-generation flue gases. With a fluvial formation geology and sharp hydraulic-conductivity contrasts, this is a challenging and novel application of CO2 EOR. The objective of this study is to obtain a reliable predictive reservoir model by integrating multidecadal production data at different temporal resolutions into the available geologic model. This will be useful for understanding flow units along with heterogeneity features and their effect on subsurface flow mechanisms, to guide the optimization of the injection scheme and maximize CO2 sweep and oil recovery from the reservoir.

Our strategy consists of a hierarchical approach for geologic-model calibration incorporating available pressure and multiphase production data. The model calibration is performed using regional multipliers, and the regions are defined using a novel adjacency-based transform accounting for the underlying geologic heterogeneity. The genetic algorithm (GA) is first used to match 70-year pressure and cumulative production by adjusting pore volume (PV) and aquifer strength. Water-injection data for reservoir pressurization before CO2 injection is then integrated into the model to calibrate the formation permeability. The fine-scale permeability distribution consisting of more than 7 million cells is reparameterized using a set of linear-basis functions defined by a spectral decomposition of the grid-connectivity matrix (Laplacian grid). The parameterization represents the permeability distribution using a few basis-function coefficients that are then updated during history matching. This leads to an efficient and robust work flow for field-scale history matching.

The history-matched model provided important information about reservoir volumes, flow zones, and aquifer support that led to additional insight compared with previous geological and simulation studies. The history-matched field-scale model is used to define and initialize a detailed fine-scale model for a CO2 pilot area that will be used to study the effect of fine-scale heterogeneity on CO2 sweep and oil recovery. The uniqueness of this work is the application of a novel geologic-model parameterization and history-matching work flow for modeling of a mature oil field with decades of production history, and which is currently being developed with CO2 EOR.
Secondary pneumomediastinum and bilateral tension pneumothorax following aneurysmal subarachnoid hemorrhage surgery: a report of five cases
Authors: Ma Haichun , Xuan Chengluan , He Kan , Wang Dan , Zhang Qunshu
Published: January 2019

Background: Simultaneous occurrence of secondary pneumomediastinum and bilateral tension pneumothorax is an uncommon complication of aneurysmal subarachnoid hemorrhage.
Case presentation: In the present study, all five patients were admitted with Hunt and Hess grade IV. Pneumomediastinum and bilateral tension pneumothorax occurred simultaneously after clipping or embolization. Tube thoracostomy and underwater sealed drainage were performed to improve oxygen saturation and hemodynamics. Of five patients, one was decided to cease treatment on the first day after surgery, three patients achieved good recovery, and one patient suffered serious disability.
Conclusions: Anesthesiologists should be aware of pneumomediastinum and bilateral tension pneumothorax occurring after surgical or neurointerventional treatment in subarachnoid hemorrhage patients with poor Hunt and Hess grade. Timely diagnosis and chest tube insertion were extremely crucial in the treatment of these patients.
Keywords: Secondary pneumomediastinum; Bilateral tension pneumothorax; Aneurysmal subarachnoid hemorrhage
Cardioprotective Effect of Remote Ischemic Preconditioning with Postconditioning on Donor Hearts in Patients Undergoing Heart Transplantation: a single-center, double-blind, randomized controlled trial
Authors: Wang Guyan , Zhang Ying , Yang Lijing , Chen Yimeng , Fang Zhongrong , Zhou Hui , Zhang Congya , Lei Guiyu , Shi Sheng , Li Jun
Published: January 2019

Background: Cardioprotective effect of remote ischemic preconditioning (RIPC) in cardiovascular surgery is controversy. This study investigated whether RIPC combined with remote ischemic postconditioning (RIPostC) reduces myocardial injury on donor hearts in patients undergoing heart transplantation.
Methods: One hundred and twenty patients scheduled for orthotopic heart transplantation were enrolled and randomly assigned to an RIPC+RIPostC group (n=60) or a control (n=60) group. In the RIPC+RIPostC group, four cycles of 5-min ischemia and 5-min reperfusion were applied on the right upper limb by a cuff inflated to 200mmHg after anesthesia induction (RIPC) and 20 minutes after aortic declamping (RIPostC). Serum cardiac troponin I (cTnI) level was determined preoperatively and at 3, 6, 12, 24 h after aortic declamping. Postoperative clinical outcomes were recorded. The primary endpoint was comparison of the cTnI levels at 6 h after aortic declamping.
Results: Compare with the preoperative baseline, serum cTnI levels peaked at 6h after aortic declamping in two groups. Compare with the control group, RIPC+RIPostC significantly reduced the serum cTnI levels at 6h after aortic declamping (38.87±31.81 vs 69.30±34.13ng/ml, P=0.018). There was no significant difference in in-hospital morbidity and mortality between the two groups.
Conclusion: In patients undergoing orthotopic heart transplantation, RIPC combined with RIPostC reduced myocardial injury at 6h after aortic declamping，while we found no evidence of this function provided by RIPC+RIPostC could improve clinical outcomes
Trial Registration: Trial Registration Number: chictr.org.cn. no. ChiCTR-INR-16010234. (Prospectively registered). The initial registration date was 9/1/2017.
Keywords: Ischemia; preconditioning; postconditioning; heart transplantation
Role of Preoperative Pregabalin in Reducing Inhalational Anaesthetic Requirements in Abdominal Hysterectomy: Randomized Controlled Trial
Authors: Mohamed Ahmed Abdalla , Ibrahim Gehan Helmy , Refai Nesrine Abd Elrahman El , Gamaleldin Tamer Mousaad Abdelhamid , Abdelrahman Reham Ali Abdelrahman , Dobal Nasser Mohamed , Atta Ehab Mohi , Ali Norhan Abdelaleem , Khair Tamer Mohamed , Osman Safinaz Hassan , Belita Mohamed Ibrahim , Seleem Ahmed A , Ismail Maha Youssef , Fahmy Rania Samir , Salem Ahmed Essam , Hady Hany Mohamed El , Elbadawy Ahmed Mohamed , Farrag Tahani
Published: January 2019

Background: preoperative oral pregabalin controls postoperative pain & decreases anesthetic requirements in total intravenous anaesthesia . In this study, we hypothesized that preoperative pregabalin reduces inhaled isoflurane requirements.
Methods: Study was conducted in a university hospital, included 50 women (18-60 yrs.), ASA I or II, admitted to undergo elective abdominal hysterectomy under general anaesthesia. Time of study: June to September 2017. Exclusion criteria were allergy or hypersensitivity to pregabalin; patients on calcium channel blockers, antiepileptic drugs, antidepression drugs, any analgesics or sedatives, or oral hypoglycemic agents; and patients with severe cardiovascular, renal, hepatic or neurological dysfunction. Interventions: giving either oral pregabalin 150 mg or placebo to patients of both groups. Primary outcome measures: inhaled isoflurane requirements to maintain haemodynamics ± 20% of baseline& bispectral index (BIS) of 40 - 60, measured using MAQUET Flow-I anaesthetic machine. Secondary outcomes : attenuation of pressor response to intubation, postoperative pain, first time for rescue analgesia, total anaglesics and adverse effects.
Results: Isoflurane consumption was significantly less in pregabalin group (7.80 ± 1.27ml h -1) versus (12.27 ± 2.49 ml h-1) in control group, (P= 0.00). Better haemodynamic stability was in pregabalin group after intubation. First postoperative hour :the mean VAS score was significantly higher in control group (7.10 ± 1.20) compared to pregabalin group (4.50 ± 1.70), P<0.001. All patients in control group received pethidine intramuscular. More patients in pregabalin group suffered dizziness.
Conclusion: preoperative pregabalin 150 mg ,1 h before total abdominal hysterectomy has an inhaled anaesthetic-sparing effect, maintain haemodynamics and optimizes postoperative analgesia.
Keywords: Gabapentinoids, Pregabalin; Inhalation Anaesthetics, Isoflurane; Monitoring, Bispectral Index; Surgery, Abdominal Hysterectomy
Objectives: We aimed to investigate the effectiveness and safety of preoperative oral pregabalin 150 mg in women undergoing elective total abdominal hysterectomy under general anaesthesia.
Design: A prospective, randomized, double-blind, controlled study.
Trial Registry Number: ClinicalTrials.gov: NCT 03302208
The comparison of the incidence of postoperative Sore Throat, Hoarseness and Myalgia between rocuronium and succinylcholine for RSII: a randomized controlled trial
Authors: Wang Jie , Du Fang , Cang Jing , Liang Chao , Xue Zhanggang
Published: January 2019

Background: The present study was designed to compare the incidence of postoperative sore throat, hoarseness, and myalgia between rocuronium and succinylcholine for rapid sequence induction and intubation.
Methods: One hundred and twenty-four patients were randomly divided into rocuroniun group (group R, n=62) or succinylcholine group (group S, n=62). Anesthesia was induced with propofol 2mg kg-1 and remifentanil 2μg kg-1in both groups, and then rocuronium 0.6 mg kg-1 or succinylcholine 1.5mg kg-1 was given after patient lost consciousness. Tracheal intubation was performed 60s after these two muscle relaxants were given and the intubating conditions were evaluated. The incidences of postoperative sore throat, hoarseness and myalgia were evaluated at postoperative care unit(PACU), 12hours 24hours and 48hours postoperatively.
Results: The numbers of patients with excellent and good intubating conditions in group R were 90.0% and 6.7%, respectively, which were comparable with those in group S (91.7% and 5.0% respectively). The incidence of postoperative sore throat of group S (41.8%) was significantly higher than that of group R (18.3%) in PACU (P<0.05), at 12 hours (38% versus 10%, P<0.05) and 24 hours postoperatively (32% versus 6.7%, P<0.05), however, these differences reached an insignificant level at 48 hours postoperatively (3.3% versus 1.7%). There were some cases in both groups underwent hoarseness and/or myalgia at each time point, but the differences did not reach a significant level.
Conclusions: In the context of a RSII with lidocaine–remifentanil–propofol, compared with rocuronium, succinylcholine supplementation was associated with high incidence of postoperative sore throat.
Trial registration: The present study was prospectively registered at http://www.chictr. org/cn/(ChiCTR-IOR-15006977); Registration date: Nov 4, 2015
Keywords: Rocuronium, Succinylcholine, Sore Throat, Hoarseness, Myalgia
(1,0) gauge theories on the six-sphere
Authors: Naseer Usman
Published: January 2019

We construct gauge theories with a vector multiplet and
hypermultiplets of (1,0)(1,0)
supersymmetry on the six-sphere. The gauge coupling on the sphere
depends on the polar angle. This has a natural explanation in terms of
the tensor branch of (1,0)(1,0)
theories on the six-sphere. For the vector multiplet we give an
off-shell formulation for all supersymmetries. For hypermultiplets we
give an off-shell formulation for one supersymmetry. We show that the
path integral for the vector multiplet localizes to solutions of the
Hermitian-Yang-Mills equation, which is a generalization of the
(anti-)self duality condition to higher dimensions. For the
hypermultiplet, the path integral localizes to configurations where the
field strengths of two complex scalars are related by an almost complex
structure.
Tarsus-Pozantı Otoyolu Kaçış Rampalarında Kullanılan Agregaların Geoteknik Özellikleri
Authors: ÇETİN Hatice Merve , ÇAKIROĞLU Mehmet
Published: January 2019

Kaçış rampaları; otoyollarda seyahat eden araçlarda mekanik sebeplerden dolayı oluşan arızalarda, aracın kendisinin daha fazla zarar görmemesi ve çevresine zarar vermemesi için yoldan uzaklaşmasını ve güvenli bir şekilde durmasını sağlayan yapılardır. Ülkemizde ilk defa 2012 yılında Tarsus-Pozantı karayolunda iki gidiş ve iki dönüş olmak üzere toplam dört adet kaçış rampası yapılmıştır. Bu kaçış rampaları açılışının ilk 2,5 ayında 5 kazayı önlemiştir. Bu çalışmada, Tarsus-Pozantı otoyolundaki kaçış rampalarında kullanılan agregaların geoteknik özellikleri araştırılmıştır. Bu kapsamda sınıflama, yuvarlaklık, birim hacim ağırlık, elek analizi,  suda yıpranma, su emme, Los Angeles aşınma kaybı, donma-çözünme, alkali-silika reaktivitesi, organik madde ve kimyasal içerik/XRF analizleri yapılmıştır. Buna göre, yuvarlak-yarı yuvarlak şekilli danelerden oluşan ve organik madde içermeyen malzemenin sınıfı GP (kötü derecelenmiş çakıl), kütle birim hacim ağırlığı 2,36 g/cm3, suda yıpranma dayanıklılığı %99,46, ağırlıkça su emme oranı %1,55, Los Angeles aşınma kaybı %20,40, donma-çözünme kütle kaybı %7,4, alkali-silika reaktivitesi zararsız olarak çıkmıştır. Bu sonuçlara göre üzerinde çalışma yapılan kaçış rampalarında  kullanılan agregalar şartname değerleri açısından uygundur. 
COMPARATIVE	ANALYSIS	OF	ACCURACY	AMONG	GLASGOW	COMA	SCALE, TRAUMA	SCORE,	AND	REVISED	TRAUMA	SCORE	AS	PREDICTORS	OF MORTALITY	HEAD	INJURY	PATIENTS
Authors: Ristanto Riki , Zakaria Amin , Nurmayunita Heny
Published: January 2019

Measurement of severity and mortality predictions in cases of head injury is an important step to support appropriate, effective and efficient clinical decision-making. Glasgow Coma Score, Trauma Score, and Revised Trauma Score are physiologycal scoring systems that can be used as predictors of mortality of head injury patients. The objective of the study was to know which scoring systems had the best accuracy as a predictor of mortality of head injured patients. The observational analytic study with this retrospective cohort design approach was carried out at dr. Iskak Tulungagung on Medical Record. Data taken from all patient medical records from January 2016 to July 2017 amounted to 150 medical records. Variables used were GCS, RTS, and TS scores when patients were admitted to hospital IGD as well as patient mortality data within 7 days of treatment. The data obtained is then processed with SPSS 20 using Mann Whitney Test, logistic regression and ROC curve comparison. Based on the results of multivariate logistic regression analysis, GCS accuracy results: sensitivity= 0.7586, specificity= 0.7934, PPV= 0.468, NPV= 0.932; RTS accuracy: sensitivity= 0.766, specificity= 0.8, PPV= 0.489, and NPV= 0.932; TS accuracy: sensitivity= 0.7, specificity= 0.783, PPV= 0.4468, NPV= 0.9126. The comparison graph analysis of ROC curve showed no significant difference of AUC between GCS, RTS, and TS because the difference was too low (<15%). There was no significant difference of accuracy between RTS, GCS, and TS use in predicting head injury mortality
NEBULIZATION	INTERVENTION	OF	ACUTE	ASTHMA	EXACERBATION	IN EMERGENCY	DEPARTMENT	:	A	LITERATURE	REVIEW
Authors: Kurniawan Dicky Endrian , Ningsih Dewi Kartikawati
Published: January 2019

Â Acute exacerbation of asthma attack are often found in the emergency room. One of the interventions that can be administered is nebulization. The aim is to developed nebulization administration protocol that can be administer to the patients. A literature review are used from journal articles were obtained from search engineer such as Google.com and ScienceDirect.com. Nebulization was depending on the severity level of the patient conditions. The option of prepartions that can be used in a mixture nebulized are salbutamol, lidocaine, and heliox. Health providers (especially nurses) must be aware to the needs of the patient to the treatment options so it can be provided appropriately. Further research are needed to develop protocol intervention, so it can be applied in clinical setting.
REDUCING	FATIGUE	SCORE	WITH	PHYSICAL	EXERCISE	IN	CHILDREN WITH	CANCER
Authors: Herman Hermalinda , Novrianda Dwi
Published: January 2019

Physical problems that often arise in children with cancer include fatigue. Fatigue or tiredness is a condition that leads to stress and a deep problem for patients suffering from cancer. Nursing interventions on cancer-related fatigue which quite effective is regular physical exercise. The purpose of this study was to identify the relationship of physical exercise with a score of fatigue in children with cancer. The method used is descriptive analytic with cross sectional study. The study was conducted in Child Care ward of DR. M.Djamil Hospital In May and October 2015. The sample in this study were 30 children with cancer who undergoing chemoteraphy that taken with accidental sampling technique. Data collection was a questionnaire about fatigue scores in children and child physical exercise performed before undergoing chemotherapy. Data were analyzed by independent t test. The mean score of fatigue in children who do physical exercise was 39.86 with a standard deviation of 6.98. In children who do not do physical exercise, the average fatigue score was 46.62 with a standard deviation of 7.60. it can be concluded that there was a significant differences in fatigue scoring between children who did physical exercise and didnt do that ( p value 0.017).In conclusion physical education programs in patients with cancer are hopefully controlled, coordinated and sustainable, and became one of the nursing intervention in patients with cancer who experience fatigue.
THE	RELATIONSHIP	BETWEEN	WORK	POSTURE	AND	RISK	FOR	LOW	BACK PAIN	COMPLAINT	OF	EMERGENCY	DEPARTMENT	NURSES	IN	dr.	DRADJAT PRAWIRANEGARA	GENERAL	HOSPITAL	SERANG	-	BANTEN
Authors: Lukmanulhakim E , Solihin Rohmat
Published: January 2019

Occupational diseases that are common are Low Back Pain. A non-ergonomic attitude and working manner will cause one to risk experiencing lower back pain. Low back pain is one of the musculoskeletal disorders caused by poor body activity. The study aimeds to determine the relationship of work posture to the risk of LBP complaints on nurses IGD RSUD dr. Dradjat Prawiranegara Serang. The study was obsevational analytics through Cross Sectional approach. Research respondents were 37 nurses used total sampling technique. Measurement of work posture used Rapid Upper Limb Assessment (RULA) and measurement of LBP complaints questionnaire used The Pain and Distress Scale. Statistical test used Chi Square test with significant level 0,05. The result of univariate analysis on work posture found that almost half of respondents (45,9%) had low risk, while (35,1%) in medium category. The result of bivariate analysis found that there was a significant correlation between the nurse worker's job and the low back pain on the nurse who worked in the Emergency Department (IGD) with the p value of 0.000. Suggestions from the results of the studied is expected for the management of the hospital to pay attention to the needs of nurses, especially related to the safety and health of workers, and also provides health education on ergonomics work posture by providing opportunities for nurses to follow informal activities related to work ergonomics.
THE	RELATIONSHIP	BETWEEN	POST	PARTUM	DEPRESSION	WITH	MOTHER-BABY EMOTIONAL	BONDING,	BREASTFEEDING	ABILITY,	MARRIAGE	SITUATION RELATIONSHIP	IN	PUSKESMAS	MALANG	REGION
Authors: Kusumawardani Putri Ragil , Poeranto Sri , Astari Asti Melani
Published: January 2019

A woman's transition into motherhood brings about physical and psychological changes. The changes require adjustments to her daily roles and activities. If the postpartum mother is not able to adapt well, then there will be a mood disorder. Depression is a part of mood disorder. The impact of postpartum depression will disrupt the mother-infant bonding, breastfeeding self-efficacy and the changing of marriage partnership. The purpose of this research was to analyze the impacts most affected by the incidence of postpartum depression in the working area of public health Malang City. The research used descriptive correlational method with cross sectional, with purposive sampling of 70 respondents in the period April 26th, 2017 - May 30th, 2017. The results are 93% of post-partum mothers experience moderate depression affecting low breast-feeding ability 54.3%, poor marital relationship situation 52.9% and moderate emotional bonding disturbances 47.1%. The result of bivariate analysis is known to the effect of postpartum depression, namely breastfeeding ability (p value = 0,011), marital relationship situation (p value = 0.014), emotional bond (p value = 0,021). The results of logistic regression test showed that the impact most influenced by postpartum depression was the ability of breastfeeding (p value = 0,011; ExpB 6,394). Postpartum mothers can predict the incidence of depression by looking at three aspects directly including the breastfeeding self-efficacy, marriage partnership and mother-infant bonding. Of the three aspects of the most influential is the breastfeeding self-efficacy. In the next research should be done at a wider population level in order to be able to cover the area of Malang generally.
EFFECT	OF	SELF	EFFICACY,	POSITIVE	BELIEF	AND	SOCIAL	SUPPORT	ON	ROLE ADAPTATION	OF	POST	PARTUM	MOTHER	WITH	POST-TRAUMA STRESS	DISORDER	(PTSD)	IN	KEDIRI	DISTRICT
Authors: Nurhidayah Reni , Poeranto Sri , Astari Asti Melani
Published: January 2019

Childbirth is a stressfull event, frequently labor can result PTSD in post partum period. The impact of post partum PTSD is a bonding issue between mother and baby that can affect the mother's ability to adapt to her new role. To Adapting with a new role mother requires an effective coping mechanism that is supported by an adequate coping source that includes self efficacy, positive belief and social support. The study describe the effect of self efficacy, positive belief and social support on adaptation of post partum mother role with PTSD. The study used cross sectional design. The sampling technique was purposive sampling and the numbers of samples were 92 respondents. The instruments for evaluate PTSD and coping was Modified PPQ, Barkin Index, PMP-SE, PPSS and PBRS. Pearson correlation test showed that all variables have p value <0,05, which means that all variables have effect on mother role adaptation. Linear Regression Test showed that self efficacy with R square 0.487 is the variable that most contribute to the mother role adaptation than the others. All variables have contribution, but self efficacy has the most significant influence on mother role adaptation. Therapeutic Activity Therapy in primary setting is needed to help pregnant women prepared adaptation
Fair Value Accounting and Earnings Management Using LLP and Realized Gains and Losses: Study in Banking Industry Listed on Indonesia Stock Exchange
Authors: Ulfa Ice Maria , Subroto Bambang , Baridwan Zaki
Published: January 2019

Abstract: Fair Value Accounting and Earnings Management Using LLP and Realized Gains and Losses: Study in Banking Industry Listed on Indonesia Stock Exchange. This study examines whether earnings management can be limited by the implementation of fair value accounting in banking industry. The main contribution of this study is  providing provide empirical evidence about the impact of fair value accounting on earnings management in Indonesia. Earnings management is proxied by loan loss provision (LLP), the realized of gains and losses, and the trade-off between realized gains and losses and LLP following Bratten et al (2013). The study provides empirical evidence that earnings management is still performed by banks, by using LLP, realized gains and losses and also occurs trade-off between LLP and realized gains and losses as means to perform earnings management in accordance with the needs of management. If banks are exposed to fair value accounting, managers will have more flexibility in reporting banks’ financial performance to present a desired earning, by  providing them with additional earning managements tools. These findings can be informative for policymakers, banking practitioners, and academics.  Keywords: earnings management, fair value accounting, LLP, realized gains and losses, trade-off LLP and realized gains and losses.Abstrak: Akuntansi Nilai Wajar dan Manajemen Laba menggunakan CKPN dan Realized Gains and Losses: Studi pada Industri Perbankan yang terdaftar di Bursa Efek Indonesia. Studi ini bertujuan untuk meneliti apakah manajemen laba dapat dibatasi oleh penerapan akuntansi nilai wajar dalam industri perbankan. Kontribusi dari penelitian ini adalah untuk memberikan bukti empiris tentang dampak penerapan akuntansi nilai wajar pada manajemen laba di Indonesia. Manajemen laba diproksikan oleh cadangan kerugian penurunan nilai (CKPN), realized of gains and losses, dan trade-off antara realized of gains and losses dan CKPN mengikuti model penelitian Bratten et al (2013). Studi ini memberikan bukti empiris bahwa manajemen laba masih dilakukan oleh bank menggunakan CKPN, realized of gains and losses dan juga terjadi trade-off antara CKPN dan realized of gains and losses sebagai sarana manajemen laba sesuai dengan kebutuhan manajemen. Konsekuensi dari paparan bank terhadap akuntansi nilai wajar dapat meningkatkan fleksibilitas manajer dalam melaporkan penghasilan yang diinginkan dengan memberikan mereka alat manajemen laba. Temuan-temuan tersebut dapat bersifat informatif bagi pembuat kebijakan, anggota industri perbankan, dan akademisi. Kata kunci: manajemen laba, akuntansi nilai wajar, CKPN, realized gains and losses, trade-off CKPN dan realized gains and losses.
Shock of Monetary Policy Transmission and Macroeconomic Variable in Indonesia: A Structural VAR Approach
Authors: Teapon Rizal Rahman H. , Mustafa Rachman Dano
Published: January 2019

Abstract: Shock of Monetary Policy Transmission and Macroeconomic Variable in Indonesia: A Structural VAR Approach. The purpose of this paper is to find out how much the shock of monetary policy transmission affects macroeconomic variables in Indonesia and vice versa by using Structural Vector Autoregression (SVAR) model. The results showed that the transmission of monetary policy in Indonesia only gives a weak influence toward inflation, but it greatly stimulates economic growth. However, the shock of macroeconomic variables influences the transmission of monetary policy in Indonesia significantly. Keywords: Structural Vector Autoregression (SVAR), monetary policy, macroeconomic policy.Abstrak: Kejutan Transmisi Kebijakan Moneter dan Variabel Makro Ekonomi di Indonesia: Suatu Pendekatan Structural Vector Autoregression. Tujuan dari tulisan ini adalah untuk mengetahui berapa besar guncangan transmisi kebijakan moneter mempengaruhi variabel makro ekonomi di Indonesia dan sebaliknya, dengan menggunakan model Structural Vector Autoregression (SVAR). Hasil penelitian menunjukan bahwa transmisi kebijakan moneter di Indonesia masih lemah dalam mempengaruhi inflasi tetapi sangat kuat dalam merangsang pertumbuhan ekonomi. Sebaliknya, guncangan variabel makro ekonomi sangat signifikan dalam mempengaruhi transmisi kebijakan moneter di Indonesia. Kata kunci: Structural Vector Autoregression (SVAR), kebijakan moneter, kebijakan makro ekonomi
Resiliencia y alfabetización socio-ecológica en el territorio
Authors: Santiago Jiménez María Evelinda
Published: January 2019

Las diferencias culturales, cuando se usan como pretexto para violentar los derechos de los demás, se convierten en un motivo principal para el exterminio, la segregación y el racismo. Sin embargo, cuando éstas son un motivo de celebración es posible crear territorios de asombro, conocimiento y reconocimiento mutuo. Cuando esto sucede, los territorios devienen en espacios de alfabetización socio-ecológica para los visitantes y son al mismo tiempo generadores de procesos de resiliencia entre sus habitantes. Aquí se propone la alfabetización reflexiva extramuros como una herramienta metodológica para la creación de territorios resilientes.
Pelatihan Teknik Asertivitas untuk Meningkatkan Self-Esteem Korban Bullying
Authors: Firdausi Amalia Hana , Adiyanti Maria Goretti
Published: January 2019

The purpose of this study is to examine the effect of assertiveness techniquestraining to improve bullying victims’ self-esteem. This study was a quasi experiment withuntreated control group with pre-test and double post-test design. The data werecollected by using adaptation instrument of Peer Interactions in Primary School (PIPS)Questionnaire, assertiveness scale, and self-esteem scale. The subjects were 18 students in4 th -5 th grade who are indicated as bullying victims and have self-esteem scores categorizedin low to moderate levels (8 students in experimental group and 10 students in controlgroup). The result of the Mann Whitney U test showed that there was no difference inself-esteem scores between the experimental and control group during the pretest (p >0.05). After being treated, the differences in self-esteem scores were significant with Z = -3.113; p = 0.002 (p < 0,01) between the experimental group and control group, in which themean score of self-esteem in the experimental group was higher than the control group
Efektivitas Remediasi Kognitif terhadap Perbaikan Fungsi Kognitif pada Penderita Skizofrenia Rawat Inap di Rumah Sakit Jiwa A di Yogyakarta
Authors: Rini Weni Susilo , Rochman Hadjam M. Noor
Published: January 2019

The aim of this reasearch to evaluate the effectiveness of cognitive remediationtherapy in improving cognitive function of schizophrenia inpatient. This research was aquasi experimental with untreated control group design with dependent pretest andposttest. Fourteen schizophrenic inpatients were assigned to either a cognitiveremediation group (n=7) or a control group (n=7). Cognitive dysfunctions were assessedusing validated Indonesian version of Cognitive Assessment Interview (CAI). Theintervention consisted of 12 sessions in 3 weeks, and was conducted in groups. ResultCognitive training group showed significant improvements in attention(effect size 0.65),working memory (effect size 0.68) and processing speed (effect size 0.61)after theintervention compared to the control group, but no significant improvement in globalcognitive function. Conclusion the research suggests that cognitive remediation is noteffective to improve global cognitive function and effective to improve attention, workingmemory and processing speed in hospitalized schizophrenic patients.
Implementing Landslide Susceptibility Map at Watershed Scale of Lompobattang Mountain South Sulawesi, Indonesia
Authors: Rasyid Abdul Rachman , Bhandary Netra Prakash , Yatabe Ryuichi
Published: January 2019

This study attempts to predict future landslide occurrence at watershed scale and calculate the potency of landslide for each sub-watershed at Lompobatang Mountain. In order to produce landslide susceptibility map (LSM) using the statistical model on the watershed scale, we identified the landslide with landslide inventories that occurred in the past, and predict the prospective future landslide occurrence by correlating it with landslide causal factors. In this study, six parameters were used namely, distance from fault, slope, aspect, curvature, distance from river and land use. This research proposed the weight of evidence (WoE) model to produce a landslide susceptibility map. Success and predictive rate were also used to evaluate the accuracy by using Area under curve (AUC) of Receiver operating characteristic (ROC). The result is useful for land use planner and decision makers, in order to devise a strategy for disaster mitigation.
Geology, Geochemistry and Hydrothermal Fluid Characteristics of Low Sulfidation Epithermal Deposit in the Sangon Area, Kokap, Special Region of Yogyakarta
Authors: Pramumijoyo Pranayoga , Idrus Arifudin , Warmada I Wayan , Yonezu Kotaro
Published: January 2019

On the basis of the previous studies and reconnaissance survey in the studyarea covering Sangon, Kalirejo, Kokap Sub-district, Kulon Progo Regency, Special Region of Yogyakarta, it reveals some facts of the occurrence of quartz veins with massive, crustiform, comb, drusy cavity, saccharoidal, granular, and reniform/mammillated textures, the appearance of lattice bladed barite and hydrothermal breccia veins. Referring to those characteristics, the deposit type in the study area is interpreted to be low sulfidation epithermal type. This study is aimed to understand and characterize the geological condition, rock and ore geochemistry and the mineralizing fluids. The alteration and ore mineralization are almost observed in entire rock units particularly the intrusive andesite 1. Their formation is controlled by the tension fractures (NW–SE and NE–SW) which associate with sinistral strike slip faults (NE–SW), dilational jog (NNW–SSE), oblique normal fault (WNW–ESE), and predictable normal fault at the NE of study area (NW–SE). The alteration zones are developed to be silica-clay (quartz-illite-kaolinite-kaolinite/smectite), argillic (smectite-illite/smectite), and propylitic (chlorite-calcite±epidote). The precipitationof ore minerals is controlled by boiling, mixing, and wall-rock alteration, and canbe found in the quartz veins (quartz-adularia-sericite) and disseminated in the alteration zones, which their high variability is only can be found in the quartz veins, including pyrite, sphalerite, chalcopyrite, galena, marcasite, and arsenopyrite. Based on the ICPAES measurement of 5 quartz vein samples, the Cu, Zn, Pb, and As grade reach about 5,171 ppm, 8,995 ppm, 6,398 ppm, 34.1 ppm, and 1,010.5 ppm, respectively. Gold is not detected. Fluid inclusion microthermometric analysis shows Th of 242.1–257.6 °C and salinity of 1.57–3.87 wt.% NaCl equiv., which indicate a depth below the paleosurface of 384–516 m, and pressure of 101.7–136.6 bar. The ore deposit in the study area is interpreted to be a deep basemetal low sulfidation epithermal type. Gold might be depleted in this epithermal type.
INCIDENTAL DETECTION OF CARCINOMA IN SITU IN FIBROADENOMA OF BREAST IN A YOUNG WOMAN: A RARE FINDING
Authors: Kairanna Nikitha Valerina , Singh Brijmohan Kumar , P Pavithra
Published: January 2019

Fibroadenoma is the most common benign tumor of the breast in young females. Breast cancer arising within a fibroadenoma is a rare phenomenon. The incidence of carcinoma within a fibroadenoma is reported to be between 0.1% and 0.3% in a screened population, with a peak age of occurrence between the 4th and 5th decade. We present a case of 29-year-old female with ductal carcinoma in situ in a background of fibroadenoma. There is a low percentage of fibroadenomas harboring carcinoma; however, all breast lumps should be seriously managed; extirpation and histological examination is recommended.