bluuebunny/crossref_metadata_2025 huggingface dataset:
Low p16 Cytoplasmic Staining Predicts Poor Treatment Outcome in Patients with p16-Negative Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving TPF Induction Chemotherapy
Authors: Chen Yen-Hao , Chien Chih-Yen , Huang Tai-Ling , Chiu Tai-Jen , Wang Yu-Ming , Fang Fu-Min , Li Shau-Hsuan
Published: January 2023

Human papillomavirus (HPV) has been proven to be associated with head and neck squamous cell carcinoma (HNSCC), and diffuse p16 unclear staining is usually considered as HPV-positive. The aim of the current study was to investigate the role of p16 cytoplasmic staining in HNSCC prognosis. A total of 195 HNSCC patients who received docetaxel, cisplatin, and 5-fluouracil (TPF) induction chemotherapy followed by chemoradiotherapy were enrolled. The status of p16 cytoplasmic staining was determined using immunohistochemistry. The median follow-up was 26.0 months for the whole study population and 90.3 months for 51 living survivors. p16 cytoplasmic staining was low in 108 patients and high in 87 patients. Low expression of p16 cytoplasmic staining and primary tumor location in the oral cavity were both independent factors indicating a worse response rate to TPF induction chemotherapy in the univariate and multivariate analyses. The logistic regression model also showed that low expression of p16 cytoplasmic staining and clinical N2–3 status were independent prognostic factors for worse progression-free survival and overall survival. Our study showed that p16 cytoplasmic staining could predict the treatment response to TPF induction chemotherapy and is an independent prognostic factor of survival in HNSCC.
A Narrative Literature Review Using Placemaking Theories to Unravel Student Social Connectedness in Hybrid University Learning Environments
Authors: Wheele Theresa , Weber Clara , Windlinger Lukas , Haugen Tore , Lindkvist Carmel
Published: January 2023

Student social connectedness is indicated to be changing with the increasing digitalisation of universities. This narrative literature review aims to bring new meanings to the hybrid university learning environment (HULE), and to develop a framework for the benefit of student social connectedness by using placemaking theories. It searches through the academic literature for evidence of experience with three attributes of social connectedness: socialising, social support, and sense of belonging, in relation to individuals’ sense of place, bringing a range of outcomes, such as identity development, which might contribute to improved social connectedness. This is then expanded in the HULE by looking at the physical and online spaces, with a focus on liminal space and co-design. The findings show that an overly rigid structure of the HULE can cause negative student social connectedness, with co-design being proposed as a way of creating a tailored and connected learning experience. However, this is underdeveloped for learning environment needs and could be enhanced by applying placemaking theories to map levels of student social connectedness in the physical location and in the more-than-real ‘non-places’. This provides an innovative perspective of the HULE based on student social connectedness, impacting the existing pedagogical approach for university courses.
Enhanced Removal of Organic Dyes Using Co-Catalytic Ag-Modified ZnO and TiO2 Sol-Gel Photocatalysts
Authors: Kaneva Nina , Bojinova Assya , Papazova Karolina
Published: January 2023

Zinc oxide and titanium dioxide semiconductor photocatalysts have been widely utilized in the last few decades for water treatment because of their high photocatalytic efficiency. Recently, a lot of researchers have focused on the improvement of the photocatalytic properties of catalysts through modifying and co-modifying them with different metals and nonmetals. These co-catalytic ions improve the photocatalytic activity of ZnO and TiO2 by reducing its energy band gap. This might be useful in wastewater treatment for the photocatalytic degradation of organic contaminants. In this study, we prepared semiconductor films that were surface-modified with Ag co-catalyst layers via the photo-fixation of Ag (I) ions with varied concentrations (10−2–10−4 M) in the water phase under UV illumination for the first time. The photocatalytic behavior was evaluated by the degradation of malachite green and methylene blue under UV and visible light irradiation. The ZnO/Ag and TiO2/Ag samples showed a faster degradation of malachite green compared to methylene blue due to the formation of stable intermediates by the reaction of OH radicals with the triarylmethane dye (C=C bond) during the photocatalysis. The co-catalytic-silver-modified films had a higher photocatalytic efficiency in comparison with the pure nanostructures. The dye photodegradation rate constants increased in the following order: pure films < films modified with Ag, 10−4 M < films modified with Ag10−3 M < films modified with Ag10−2 M. The Ag modification and the heterojunction of the composites contributed to trapping and transfer of the electrons. Therefore, the photogenerated charges had a longer lifetime, resulting in a strengthened photocatalytic ability of the ZnO/Ag and TiO2/Ag films.
Methanol Steam Reforming over La1-xSrxCeO3-δ Catalysts for Hydrogen Production: Optimization of Operating Parameters
Authors: Chen Gaokui , Shen Qiuwan , Zhang Xin , Cai Zhongwen , Shao Zicheng , Li Shian , Yang Guogang
Published: January 2023

In this study, a series of A-site strontium-doped La1-xSrxCeO3-δ (x = 0.2, 0.4, 0.6, 0.8) perovskite catalysts were synthesized via the ethylenediaminetetraacetic acid (EDTA) sol-gel method for hydrogen production by methanol steam reforming. The fresh and the reduced catalysts are characterized by scanning X-ray (XRD), energy dispersive X-ray spectroscopy (EDS) and scanning electron microscopy (SEM) techniques. Results showed that La0.6Sr0.4CeO3-δ exhibited the best performance among the La1-xSrxCeO3-δ catalysts. The operating parameters were optimized to study the catalytic performance of La0.6Sr0.4CeO3-δ, including catalytic temperature, water–methanol ratio (W/M) and liquid hourly space velocity (LHSV). However, the excessive strontium content led to a decrease in hydrogen production amount per unit time, and the high W/M promoted the reverse water–gas shift reaction (RWGS), which resulted in a decrease in CO selectivity and an increase in CO2 selectivity. In addition, the optimal reaction parameters are as follows: reforming temperature of 700 °C; W/M of 3:1; LHSV of 20 h−1. Furthermore, the methanol conversion rate of La0.6Sr0.4CeO3-δ can reach approximately 82%, the hydrogen production can reach approximately 3.26 × 10−3 mol/g(cat)/min under the optimum reaction conditions. Furthermore, La0.6Sr0.4CeO3-δ exhibits high hydrogen selectivity (85%), which is a promising catalyst for MSR application.
1,3-Butadiene Production Using Ash-Based Catalyst
Authors: Bojang Adama A. , Wu Ho Shing
Published: January 2023

The production of 1,3-butadiene from ethanol was carried out using ash as a catalyst in combination with Zr and Mg. The catalytic experiments were carried out at 350–400 °C with a different weight hourly space velocity (WHSV). The catalysts that were used were combined as follows: Ash, Ash:MgO (weight ratio 1:1), Ash:MgO (1:2), Ash:MgO (1:3), and Ash: MgO/ZrO2 (1:1:1). The characterization of the catalyst was carried out using BET, SEM, XRD, TGA, and XPS, respectively. The yield of 1,3-butadiene using bare ash was 65% at 400 °C and 2.5 h−1 of WHSV. Using the Ash:MgO (1:2) catalyst led to an ethanol conversion rate of 79 % at 350 °C; the yield and selectivity of 1,3-butadiene were 48% and 87.8 %, respectively. Using the Ash:MgO(1:3) catalyst led to a 1,3-butadiene yield of 25% and a selectivity of 82% at 350 °C. The Ash:MgO(1:2) catalyst had a 1,3-butadiene yield of 50% and selectivity of 83%, and the Ash:MgO(1:1) had a 1,3-butadiene yield of 30% and selectivity of 80%, while the Ash:MgO/ZrO2 (1:1:1) catalyst had a 1,3-butadiene yield of 50% and selectivity of 90.8% at 2.5 h−1 of WHSV.
Research Progress on Catalytic Combustion of Volatile Organic Compounds in Industrial Waste Gas
Authors: Li Kai , Luo Xiaoqing
Published: January 2023

Volatile organic compounds (VOCs) emitted from industrial processes have high stability, low activity, and toxicity which cause continuous harm to human health and the atmospheric environment. Catalytic combustion has the advantages of low energy consumption and low cost and is expected to be one of the most effective methods to remove VOCs. At present, the selection of low cost, high activity, and durability catalysts are still a difficult problem. Industrial emissions of VOCs contain a certain amount of aromatic hydrocarbons; these substances are highly toxic substances, and, once inhaled by the human body, will cause serious harm to health. In this paper, the principle, advantages, and disadvantages of VOCs processing technology are analyzed in detail, and the catalytic combustion of aromatic hydrocarbons in VOCs is reviewed, including catalyst, reaction conditions, catalyst selection, inactivation reasons, and structure use. In addition, the deactivation effects of chlorine and sulfur on catalysts during the catalytic combustion of VOCs are discussed in detail. Finally, on the basis of literature research, the prospect of catalytic combustion of VOCs is presented, which provides influential information for further research on VOCs processing technology.
Detection of Low-Level Adulteration of Hungarian Honey Using near Infrared Spectroscopy
Authors: Bodor Zsanett , Majadi Mariem , Benedek Csilla , Zaukuu John-Lewis , Veresné Bálint Márta , Csajbókné Csobod Éva , Kovacs Zoltan
Published: January 2023

Honey adulteration is a worldwide problem; however, its detection is a challenge for researchers and authorities. There are numerous ways of honey counterfeiting; amongst them, direct adulteration is one of the most common methods. Correlative techniques, such as near-infrared spectroscopy (NIRS), are useful tools in the detection of honey adulteration; however, this method has not been applied to Hungarian honeys. The aim of this research was to investigate the performance of NIRS for the detection of sugar syrup addition to Hungarian honeys at lower concentration levels (<10% w/w). Acacia, rape, forest, sunflower, and linden honeys were mixed with high-fructose-content sugar syrup, rice syrup, or self-made glucose fructose syrup in 3%, 5%, and 10% w/w. NIRS analysis was performed in the spectral range of 950–1650 nm. Principal component analysis was coupled with linear discriminant analysis and partial least square regression models were built for the classification and prediction of adulteration levels, respectively. Our results showed that the performance of NIRS highly depends on both type of syrup and honey. PCA-LDA models provided the 100% correct classification of control in the case of all the models, while PLSR results could predict the added sugar syrup content in the case of rice and F40 syrup models, obtaining >2.2 RPDCV value.
A Creative and Movement-Based Blended Intervention for Children in Outpatient Residential Care: A Mixed-Method, Multi-Center, Single-Arm Feasibility Trial
Authors: Birnkammer Susanne , Calvano Claudia
Published: January 2023

The COVID-19 pandemic led to psychological distress among children and adolescents. Due to multiple psychosocial burdens, the youth in residential care were especially exposed to an increased risk of mental health problems during the pandemic. In a multi-center, single-arm feasibility trial, N = 45 children and adolescents aged 7–14 years were allocated to a 6-week blended care intervention, conducted in six outpatient residential child welfare facilities. The intervention covered a once weekly face-to-face group session for guided creative (art therapy, drama therapy) and movement-oriented (children’s yoga, nature therapy) activities. This was accompanied by a resilience-oriented mental-health app. Feasibility and acceptance analyses covered app usage data and qualitative data. Effectiveness was determined by pre-post comparisons in quantitative data on psychological symptoms and resources. Further, subgroups for poorer treatment outcome were explored. The intervention and app were considered to be feasible and were accepted by residential staff and the children. No significant pre-post changes were found across quantitative outcomes. However, being female, being in current psychosocial crisis, a migration background, or a mentally ill parent were correlated with change in score of outcomes from baseline. These preliminary findings pave the way for future research on blended care interventions among at-risk children and adolescents.
Characterization and Sensory Evaluation of a Cosmeceutical Formulation for the Eye Area with Roasted Coffee Oil Microcapsules
Authors: Böger Bruna Raquel , Lonni Audrey Alesandra Stinghen Garcia , Benassi Marta de Toledo
Published: January 2023

The objective of this work was to characterize a cosmeceutical formulation for the eye area with roasted coffee oil microcapsules (MOF) and evaluate the acceptance and effects of its use by consumers. MOF had 3% microcapsules produced by complex coacervation; a basic formulation (BF) was used for comparison. The addition of microcapsules did not affect the pH (4.52), density (0.99 g mL−1), consistency (0.77 N s), and viscosity index (0.25 N s) of the formulation. However, a reduction in spreadability, firmness, and cohesiveness was observed. The 58 assessors received one kit with the formulations and a notebook with instructions to carry out the tests at home. They were instructed to apply the cream for 28 days and evaluate the attributes of application and treatment effects on 7-point category scales. The effect of oil addition observed in the physical tests was not sensorially perceived for spreadability and tackiness (6.0 and 5.6, respectively), indicating approval and easiness of application. The perception of the benefits (increase in smoothness, hydration, firmness, elasticity, and skin general appearance, and reduction in signs of fatigue and wrinkles/fine lines) was similar comparing MOF and BF. In conclusion, the coffee oil microcapsule is a viable ingredient for dermocosmetics with sensory acceptance.
pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions
Authors: Salinas-García Mª Carmen , Plaza-Garrido Marina , Gavira Jose A. , Murciano-Calles Javier , Andújar-Sánchez Montserrat , Ortiz-Salmerón Emilia , Martinez Jose C. , Cámara-Artigas Ana
Published: January 2023

The PDZ domains are modular domains that recognise short linear C-terminal sequences in proteins that organise the formation of complex multi-component assemblies. We have crystallised the third PDZ domain of the neuronal postsynaptic density-95 protein (PSD95-PDZ3) at mildly acidic pH conditions and obtained up to four polymorphs. Thus, below pH 4.0, the protein crystallised into prism-shaped crystals that belonged to the trigonal space group P3112. In contrast, above this pH value, the crystals’ shape changes to long needles belonging to the monoclinic P21 and two different orthorhombic packings of the P212121 space group. In addition, all the polymorphs share the main crystallographic interface, where the sidechain of the Asp332 imitates the binding of the C-terminal moiety to the canonical binding motif. Furthermore, we have analysed how changes in the ionisation state of some specific residues might be critical for crystallising the different polymorphs. The analysis of these polymorphs provides clues on the relevance of specific protein-protein interactions in protein crystallisation. However, these structures allow dissecting those electrostatic interactions that play a role in the conformation adopted by some residues and the extra-domain components upon binding C-terminal sequences.
Evaluation of Current Antiemetic Therapy Response in Patients Undergoing MEC or HEC Regimens in Portugal
Authors: Araújo António , Tavares Nuno , Faria Ana Luísa , Gomes Rosa , Mendonça Joana Carvalho , Parente Bárbara , Capela Andreia , Barata Fernando , Macedo Ana
Published: January 2023

Chemotherapy-induced nausea and vomiting (CINV) negatively impact cancer patients’ quality of life and treatment outcomes. This study evaluated the achievement of complete response to CINV prophylaxis during the first five days after chemotherapy in adult outpatient cancer clinics with solid malignant tumours receiving Moderate or Highly Emetogenic Chemotherapy (MEC or HEC) in Portugal. During the study, patients completed three evaluations, and nausea severity and CINV impact on patients’ daily life was assessed. A complete response (no emetic episodes, no use of rescue antiemetic medication, and no more than mild nausea) was observed in 72% of the cycles (N = 161) throughout the five days after chemotherapy. Amongst the patient population, 25% classified their CINV episodes as severe. Though more than half of the patients achieved a complete response, suggesting that a therapeutic effort is being made to minimise this side effect, the overall scenario is barely optimistic. Significantly, new CINV-control measures in MEC/HEC patients should be adopted, specifically avoiding the single use of dexamethasone and 5-HT3 and raising awareness of using NK1-RAs. Thus, it is critical to improve CINV prophylactic treatment and implement practical international antiemetic guidelines in Portuguese clinical practice, envisaging the improvement of supportive care for cancer patients.
A Retrospective Study of Renal Growth Changes after Proton Beam Therapy for Pediatric Malignant Tumor
Authors: Li Yinuo , Mizumoto Masashi , Oshiro Yoshiko , Nitta Hazuki , Saito Takashi , Iizumi Takashi , Kawano Chie , Yamaki Yuni , Fukushima Hiroko , Hosaka Sho , Maruo Kazushi , Kamizawa Satoshi , Sakurai Hideyuki
Published: January 2023

The purpose of this study was to analyze renal late effects after proton beam therapy (PBT) for pediatric malignant tumors. A retrospective study was performed in 11 patients under 8 years of age who received PBT between 2013 and 2018. The kidney was exposed in irradiation of the primary lesion in all cases. Kidney volume and contour were measured on CT or MRI. Dose volume was calculated with a treatment-planning system. The median follow-up was 24 months (range, 11–57 months). In irradiated kidneys and control contralateral kidneys, the median volume changes were −5.63 (−20.54 to 7.20) and 5.23 (−2.01 to 16.73) mL/year; and the median % volume changes at 1 year were −8.55% (−47.52 to 15.51%) and 9.53% (−2.13 to 38.78%), respectively. The median relative volume change for irradiated kidneys at 1 year was −16.42% (−52.21 to −4.53%) relative to control kidneys. Kidneys irradiated with doses of 10, 20, 30, 40, and 50 GyE had volume reductions of 0.16%, 0.90%, 1.24%, 2.34%, and 8.2% per irradiated volume, respectively. The larger the irradiated volume, the greater the kidney volume was lost. Volume reduction was much greater in patients aged 4–7 years than in those aged 2–3 years. The results suggest that kidneys exposed to PBT in treatment of pediatric malignant tumor show continuous atrophy in follow-up. The degree of atrophy is increased with a higher radiation dose, greater irradiated volume, and older age. However, with growth and maturation, the contralateral kidney becomes progressively larger and is less affected by radiation.
Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment
Authors: Furtsev Taras V. , Koshmanova Anastasia A. , Zeer Galina M. , Nikolaeva Elena D. , Lapin Ivan N. , Zamay Tatiana N. , Kichkailo Anna S.
Published: January 2023

Dental implant therapy is a well-accepted treatment modality. Despite good predictability and success in the early stages, the risk of postplacement inflammation in the long-term periods remains an urgent problem. Surgical access and decontamination with chemical and mechanical methods are more effective than antibiotic therapy. The search for the optimal and predictable way for peri-implantitis treatment remains relevant. Here, we evaluated four cleaning methods for their ability to preserve the implant’s surface for adequate mesenchymal stem cell adhesion and differentiation. Implants isolated after peri-implantitis were subjected to cleaning with diamond bur; Ti-Ni alloy brush, air-flow, or Er,Cr:YSGG laser and cocultured with mice MSC for five weeks. Dental bur and titanium brushes destroyed the implants’ surfaces and prevented MSC attachment. Air-flow and laser minimally affected the dental implant surface microroughness, which was initially designed for good cell adhesion and bone remodeling and to provide full microbial decontamination. Anodized with titanium dioxide and sandblasted with aluminum oxide, acid-etched implants appeared to be better for laser treatment. In implants sandblasted with aluminum oxide, an acid-etched surface better preserves its topology when treated with the air-flow. These cleaning methods minimally affect the implant’s surface, so it maintains the capability to absorb osteogenic cells for further division and differentiation.
Energy Efficiency Optimization of Collaborative Power Supply System with Supercapacitor Storages
Authors: Deng Yibo , Li Chushan , Deng Yan , Chen Ting , Feng Shaoyu , Chu Yujie , Li Chengmin
Published: January 2023

To solve the challenge of low efficiency and high operation cost caused by intermittent high-power charging in an energy storage tram, this work presents a collaborative power supply system with supercapacitor energy storage. The scheme can reduce the peak power of the transformer, therefore reducing the grid-side capacity and improving the efficiency. However, there is a lack of quantitative analysis on the performance improvement of the solution. The energy efficiency models of critical components are proposed to evaluate the efficiency of the system, and energy efficiency optimization is conducted. Taking an operational tram line as an example, the improved charging efficiency and reduced operating costs are derived. Further, the ground energy storage capacity is designed and implemented. The measured data demonstrates that the energy efficiency of the optimized charging system is improved, which proves its effectiveness and practicability.
Design for Reducing Bearing Force Ripple and Torque Ripple of Integrated Magnetic Bearing Motor through Halbach Array
Authors: Yang In-Jun , Hong Min-Ki , Lee Ju , Kim Won-Ho , Jung Dong-Hoon
Published: January 2023

When a magnetic bearing is used in the design of a high-speed motor, no friction and wear occur because of the principle of magnetic levitation; however, the size of the entire system increases. An integrated magnetic bearing motor is a motor with a magnetic bearing inserted inside the rotor that can minimize the increase in the size of the entire system. In this study, a method to reduce the bearing force ripple and torque ripple of an integrated magnetic bearing motor through parameters for a Halbach array and permanent magnet tapering is proposed. When designing an integrated magnetic bearing motor, because the magnetic bearing is located inside the rotor, the influence of the magnetic flux of the rotor and stator on the magnetic flux of the magnetic bearing should be minimized. By combining the magnetic fluxes of the magnetic bearing, rotor, and stator at the rotor back yoke, magnetic saturation occurs, and the performance of the bearing force and torque ripples decreases. The bearing force and torque according to the Halbach array and permanent magnet tapering were analyzed using finite element analysis. The average bearing force and torque were maximized, and the ripple was minimized through the rotor parameters. Thus, the validity of the main design variables selected to improve the output characteristics was confirmed.
Multidimensional Risk-Based Real Options Valuation for Low-Carbon Cogeneration Pathways
Authors: Al-Obaidli Houd , Govindan Rajesh , Al-Ansari Tareq
Published: January 2023

Energy price fluctuations pose a significant risk and uncertainty to financial investments for new developments in conventional power and freshwater cogeneration facilities. This study attempts to address the problem of making robust valuation for low-carbon energy project investments subject to multi-dimensional price risk, particularly looking at some key research questions: (a) how does the correlation structure, or independence, between the price risks affect the project value; and (b) does adding flexibility in investment enhance or worsen the project valuation, given (a). This study identified three price factors with significant fluctuations that impact conventional power generation, namely: wholesale electricity spot price, natural gas spot price, and CO2 market price. The price factors were used to construct a multidimensional risk model and evaluate investment decisions for cogeneration project expansion in the future based on a low-carbon energy mix. To this end, five cogeneration configurations using combined-cycle gas turbine (CCGT) integrated with solar photovoltaics (PV) and carbon capture and storage (CCS) technologies were assessed. A combined price risk was initially estimated by transforming the given price factors representing maximum covariance using principal component analysis (PCA). The trend and volatilities in the major principal component scores (the combined price risk indicator) were modelled using the geometric Brownian motion stochastic process, whose parameters were determined and then used to perform time-series simulation and generate multiple realisations of the principal component. A back transformation was then applied to obtain the simulated values representing future uncertainties in the price factors. The effect of price risk and uncertainties were subsequently evaluated using a recombining binomial lattice model for real options analysis (ROA). There were financial gains when PV was mixed with conventional natural gas-fired technology. Investment in cogeneration configurations with (a) 25% PV share provided a 53% gain in the extended net present value (e–NPV); and (b) 50% PV share provided a 124% e–NPV gain when compared to the baseline cogeneration system with no PV shares. The analyses demonstrate that PV technology is a better hedging option than CCS against future market uncertainty and price volatility.
Development of Greenhouse Gas Emission and Evaluation of Carbon Resource Use in Chosen EU Countries
Authors: Domaracká Lucia , Taušová Marcela , Čulková Katarína , Tauš Peter , Gomboš Peter
Published: January 2023

The EU presently orientates its policy to a low-carbon and resource-efficient economy. In this paper, we evaluate the current situation and the developments in greenhouse gas emissions, and we will evaluate carbon resource usage in chosen EU countries from the viewpoint of greenhouse gas emission per capita, energy production in the EU, energy dependence of EU countries, and final energy consumption. We will analyze and evaluate the data available from the Eurostat database through regression and cluster analysis using JMP 15 statistical software. The results show significant differences in the individual countries, and they can be used for determination of the energy policy in the individual states.
Toward the Instrumentation and Data Acquisition of a Tidal Turbine in Real Site Conditions
Authors: Murray Robynne E. , Simms Andrew , Bharath Aidan , Beach Ryan , Murphy Mark , Kilcher Levi , Scholbrock Andy
Published: January 2023

The National Renewable Energy Laboratory manufactured, instrumented, and deployed thermoplastic composite blades and a data acquisition system (NDAQ) on one of Verdant Power’s Gen5d 5 m diameter tidal turbines in New York’s East River. The thermoplastic blades had internal strain gages, and the NDAQ was a stand-alone system for monitoring and recording the strain and angular position of the blades. The turbine with thermoplastic blades operated and produced power successfully for 3 months, contributing energy to the New York City electric grid. The NDAQ hardware, instrumentation, and structure all survived the deployment and were still functional upon retrieval of the system, but no data were collected. Even though the data retrieval was not a success, data acquisition for deployed subsea marine renewable structures is a new undertaking, and it is critical to share lessons learned from national laboratory experiences. The successful deployment of thermoplastic composite blades marks a significant advancement toward improved materials for subsea components, as well as an advancement in recyclable composite materials. This article outlines the methodology and lessons learned for the instrumentation and data acquisition system.
A Hybrid Approach for Low-Voltage AC Series Arc Fault Detection
Authors: Liu Yu-Jen , Chen Cheng-I , Fu Wei-Chung , Lee Yih-Der , Cheng Chin-Chan , Chen Yen-Fu
Published: January 2023

In a low-voltage electric distribution network, arc fault presents a high energy density electricity-discharging phenomenon between conductors, which is often caused by aging of electric facilities, loose contacts and terminals, or insulation failure due to internal and external destructions. A large amount of heat may be created during this discharging, which will further cause the risk of fire hazards to mitigate in the residential environment. Currently, many utility grid operators and electricity users are still devoted to seeking effective detection technology for arc fault protection. This paper proposes a hybrid approach that combines discrete wavelet transform (DWT), empirical mode decomposition (EMD), and dynamic time warping (DTW) methods for low-voltage AC series arc fault detection. In DWT, it uses time–frequency domain characteristics of the arc current signal to extract the occurrence of arc fault. In EMD, it decomposes the complex arc fault current signal into a finite intrinsic mode (IMF) signal; then, instantaneous amplitude of IMF signal is obtained by Hilbert–Huang transform (HHT) as a feature for arc fault identification. Firstly, the results of arc fault detections depend on the results from DWT and EMD. When both two methods detect different results, DTW method will be activated, using the similarity measurements between normal and arc fault current waveforms as an assistant measure to determine the occurrence of arc fault. The performance of the proposed approach is tested and validated using various electric appliances, and the results show that the proposed approach can effectively detect low-voltage AC series arc fault.
Efficiency of the Consumption of Energy in the Road Transport of Goods in the Context of the Energy Crisis
Authors: Milewski Dariusz , Milewska Beata
Published: January 2023

Transport costs are strongly influenced by fuel prices and fuel consumption in transport, i.e., energy efficiency. The aim of the article is to present the problem of energy efficiency in freight transport with the use of Heavy Duty Vehicles (HDV). The authors presented the factors of energy efficiency in road transport, energy efficiency of the road vehicles, the share of fuel costs in the total costs of transport companies and the relationship between the increase in fuel prices and the increase in transport rates. Research methods include, apart from literature analysis, interviews conducted in Polish transport companies in 2022 and the analysis of data collected by the authors on the transport services market over the last 20 years. The increase in rates over the last 20 years, until 2021, largely coincided with the increase in fuel prices, while in 2022, for the first time in this period, the increase in fuel prices was greater than the increase in rates. However, the prices for transport services increased with the increase in energy consumption costs, not with changes in fuel prices. The cost of energy consumption depends on the efficiency of its use, which is constantly increasing, although to a small extent. Research shows that the efficiency of fuel consumption in high-tonnage transport changes at a rate of 0.8–1% per year while the proportion of fuel costs in Polish transport companies transporting goods by road in the last 20 years oscillates between 29% and 46%. There was also an increase in the freight rates on this market, in most cases by over 30%. Despite this, however, the profitability of some companies deteriorated. A large increase in transport rates, compensating for the increase in fuel prices, applies mainly to transport companies whose strategy is to compete with the quality of services, and when high-value loads are transported, while a small increase in transport rates, which does not compensate for the increase in fuel prices, applies mainly to companies whose strategy is to compete on the price of transport services and when low-value cargo is being transported. The results of research on the market in Poland conducted by the authors of the article agrees with the results and opinions of other authors and researchers from other countries. The authors also agree with the view that the possibilities of increasing the efficiency of energy consumption in road transport by the carriers themselves are limited. The road transport market, especially in Poland, is highly competitive, which results in high efficiency of transport processes. However, this efficiency is largely affected by factors beyond the control of these companies (technological factors, infrastructure and energy sources). It seems that the involvement of the state is necessary. The research carried out by the authors of the article also confirmed the existing relationships between the weight of the transported cargo and energy consumption identified by other authors.
Speed Tracking Performance for a Coreless Linear Motor Servo System Based on a Fitted Adaptive Fuzzy Controller
Authors: Luo Meizhu , Duan Ji-an , Yi Zhaoxi
Published: January 2023

Fuzzy control is widely used in linear motor servo systems. However, simple fuzzy rules reduce the control accuracy of the servo system, while complex fuzzy rules reduce the speed of its decision making. This paper proposes a fitted adaptive fuzzy controller (FAFC) to improve the speed tracking performance of a coreless linear motor servo system. The FAFC took a planned curve as a motion target. The planned curve is compounded by multiple performance curves of fuzzy control under the same given input. These multiple performance curves cover the variation range of motor parameters, which are offline-obtained. The performance of the planned curve is ensured by the multiple offline performance curves. The FAFC only needs simple fuzzy rules to fit the planned curve, and achieves high control accuracy without affecting the decision speed. The experimental results verified the feasibility of an FAFC. This research shows that an FAFC can effectively shorten the online calculation time of complex algorithms and keep the consistency of performance.
Design Enhancement of Eductor for Active Vapor Transport and Condensation during Two-Phase Single-Species Flow
Authors: Koirala Ravi , Ve Quoc Linh , Rupakheti Eliza , Inthavong Kiao , Date Abhijit
Published: January 2023

This study is focused on enhancing secondary vapor entrainment and direct-contact condensation in a water jet eductor for the purpose of developing a compact, medium-scale desalination system. It encompasses an extended investigation of an eductor as a condenser, or heat exchanger, for the entrained phase. Exergy study, experimental measurement, and computational analysis are the primary methodologies employed in this work. The target parameters of the optimization work were set through exergetic analysis to identify the region of maximum exergy destruction. In the case of water and water vapor as primary and secondary fluids, mixing and condensation initiates in the mixing chamber of the eductor and is where the maximum exergy destruction was calculated. Therefore, multi-jet primary nozzle eductors were studied to determine the effect of increased interphase interaction area on the exergy destruction and the maximum suction and cooling capacities. Increases in the entrainment ratio, condensation rate and heat transfer coefficient were noted for increasing numbers of nozzles when comparing one-, two- and three-jet eductors.
Evolution of Equipment in Electromobility and Autonomous Driving Regarding Safety Issues
Authors: Katis Christodoulos , Karlis Athanasios
Published: January 2023

Over the years, an increase in the traffic of electric and hybrid electric vehicles and vehicles with hydrogen cells is being observed, while at the same time, self-driving cars are appearing as a modern trend in transportation. As the years pass, their equipment will evolve. So, considering the progress in vehicle equipment over the years, additional technological innovations and applications should be proposed in the near future. Having that in mind, an analytical review of the progress of equipment in electromobility and autonomous driving is performed in this paper. The outcomes of this review comprise hints for additional complementary technological innovations, applications, and operating constraints along with proposals for materials, suggestions and tips for the future. The aforementioned hints and tips aim to help in securing proper operation of each vehicle part and charging equipment in the future, and make driving safer in the future. Finally, this review paper concludes with a discussion and bibliographic references.
An Environmental and Technical Evaluation of Vacuum-Based Thin Film Technologies: Lithium Niobate Coated Cathode Active Material for Use in All-Solid-State Battery Cells
Authors: Wolff Deidre , Weber Svenja , Graumann Tobias , Zebrowski Stefan , Mainusch Nils , Dilger Nikolas , Cerdas Felipe , Zellmer Sabrina
Published: January 2023

Research on All-Solid-State Batteries (ASSBs) currently focuses on the development of innovative materials, cell concepts, and production processes, aiming to achieve higher energy densities compared to other battery technologies. For example, it is been demonstrated that coating the Cathode Active Material (CAM) can enhance the rate capability and cycle life and reduce the interfacial resistance of an ASSB cell. For this reason, various techniques for coating the CAM have been explored, along with a variety of coating materials, including lithium niobate. Since ASSBs are still an emerging technology, more research is needed to determine how their production processes will perform from a technical, economic, and environmental perspective. In this paper, two innovative techniques for producing lithium niobate-coated CAMs are presented and evaluated. Particularly, Atomic Layer Deposition (ALD) and Physical Vapor Deposition (PVD) techniques for coating NCM811 particles are investigated. The methodology for environmental and technical feasibility assessments at an early stage of development is further presented and discussed. Based on process-specific data and expert knowledge, an environmental assessment is conducted and further supported with a qualitative technical feasibility assessment. The results help guide early-stage decision-making regarding the identification of promising process routes with relatively low impacts.
How Cooking Time Affects In Vitro Starch and Protein Digestibility of Whole Cooked Lentil Seeds versus Isolated Cotyledon Cells
Authors: Duijsens Dorine , Verkempinck Sarah H. E. , De Coster Audrey , Pälchen Katharina , Hendrickx Marc , Grauwet Tara
Published: January 2023

Lentils are sustainable sources of bioencapsulated macronutrients, meaning physical barriers hinder the permeation of digestive enzymes into cotyledon cells, slowing down macronutrient digestion. While lentils are typically consumed as cooked seeds, insights into the effect of cooking time on microstructural and related digestive properties are lacking. Therefore, the effect of cooking time (15, 30, or 60 min) on in vitro amylolysis and proteolysis kinetics of lentil seeds (CL) and an important microstructural fraction, i.e., cotyledon cells isolated thereof (ICC), were studied. For ICC, cooking time had no significant effect on amylolysis kinetics, while small but significant differences in proteolysis were observed (p < 0.05). In contrast, cooking time importantly affected the microstructure obtained upon the mechanical disintegration of whole lentils, resulting in significantly different digestion kinetics. Upon long cooking times (60 min), digestion kinetics approached those of ICC since mechanical disintegration yielded a high fraction of individual cotyledon cells (67 g/100 g dry matter). However, cooked lentils with a short cooking time (15 min) showed significantly slower amylolysis with a lower final extent (~30%), due to the presence of more cell clusters upon disintegration. In conclusion, cooking time can be used to obtain distinct microstructures and digestive functionalities with perspectives for household and industrial preparation.
Current Developments of Analytical Methodologies for Aflatoxins’ Determination in Food during the Last Decade (2013–2022), with a Particular Focus on Nuts and Nut Products
Authors: Schincaglia Andrea , Aspromonte Juan , Franchina Flavio A. , Chenet Tatiana , Pasti Luisa , Cavazzini Alberto , Purcaro Giorgia , Beccaria Marco
Published: January 2023

This review aims to provide a clear overview of the most important analytical development in aflatoxins analysis during the last decade (2013–2022) with a particular focus on nuts and nuts-related products. Aflatoxins (AFs), a group of mycotoxins produced mainly by certain strains of the genus Aspergillus fungi, are known to impose a serious threat to human health. Indeed, AFs are considered carcinogenic to humans, group 1, by the International Agency for Research on Cancer (IARC). Since these toxins can be found in different food commodities, food control organizations worldwide impose maximum levels of AFs for commodities affected by this threat. Thus, they represent a cumbersome issue in terms of quality control, analytical result reliability, and economical losses. It is, therefore, mandatory for food industries to perform analysis on potentially contaminated commodities before the trade. A full perspective of the whole analytical workflow, considering each crucial step during AFs investigation, namely sampling, sample preparation, separation, and detection, will be presented to the reader, focusing on the main challenges related to the topic. A discussion will be primarily held regarding sample preparation methodologies such as partitioning, solid phase extraction (SPE), and immunoaffinity (IA) related methods. This will be followed by an overview of the leading analytical techniques for the detection of aflatoxins, in particular liquid chromatography (LC) coupled to a fluorescence detector (FLD) and/or mass spectrometry (MS). Moreover, the focus on the analytical procedure will not be specific only to traditional methodologies, such as LC, but also to new direct approaches based on imaging and the ability to detect AFs, reducing the need for sample preparation and separative techniques.
Olive Leaf Tea Impact on Postprandial Glycemia: A Randomized Cross-Over Trial
Authors: Meireles Manuela , Cortez-Ribeiro Anna , Polck Denise , Almeida-de-Souza Juliana , Ferro-Lebres Vera
Published: January 2023

This study investigates the effect of olive leaf tea (OLT) on postprandial glycemia in healthy volunteers when ingested with a high-carbohydrate meal, compared with a placebo tea (CON). Healthy adults participated in a double-blind, randomized, placebo-controlled, and cross-over design trial receiving a high-rich carbohydrate meal with either 250 mL of OLT or CON at two different times after a washout period. The sequence order was randomized at a ratio of 1:1. Capillary blood glucose was measured in a 2 h period after ingestion. Eighteen participants were initially randomized. Of these, thirteen completed the trial and were analyzed. The consumption of OLT resulted in a delay in peak time (48.5 ± 4.2 min vs. 35.7 ± 4.0 min, p = 0.03) and a significant increase in glucose area under the curve compared to placebo (14,502.7 ± 640.8 vs. 13,633.3 ± 869.4 mg/dL·min, p = 0.03). Results are depicted as mean ± SEM. The OLT and CON palatability were generally well accepted. No adverse effects were reported. OLT did not ameliorate a glycemic curve induced by carbohydrate-rich meal ingestion, suggesting that at least when ingested acutely in a single meal, OLT does not have antihyperglycemic effects. Future studies should account for chronic consumption providing a better understanding of glycemic regulation over time.
Valorization of Rice Husk (Oryza sativa L.) as a Source of In Vitro Antiglycative and Antioxidant Agents
Authors: Frosi Ilaria , Vallelonga Daniela , Colombo Raffaella , Milanese Chiara , Papetti Adele
Published: January 2023

Rice husk is a good source of polyphenols, but it has not been efficiently utilized in food applications yet. Therefore, the aim of this work is to investigate, by in vitro assays, the polyphenolic extract (RHE) capacity of this waste to counteract the protein glycation at different stages of the reaction, correlating this activity with the antiradical properties. A microwave-assisted extraction using hydro-alcoholic solvents was applied to recover husk polyphenols. Extraction parameters were optimized by the design of the experiment. The extract with the highest polyphenolic recovery was obtained at 500 W and 90 °C, using 1:35 g of dry material/mL solvent, 80% ethanol, and a 5 min extraction time. Results highlight the ability of RHE to inhibit the formation of fructosamine in the early stage of glycation with a dose-dependent activity. Furthermore, in the middle stage of the reaction, the highest RHE tested concentration (2.5 mg/mL) almost completely inhibit the monitored advanced glycation end products (AGEs), as well as showing a good trapping ability against α-dicarbonyl intermediates. A strong positive correlation with antioxidant activity is also found. The obtained results are supported by the presence of ten polyphenols detected by RP-HPLC-DAD-ESI-MSn, mainly hydroxycinnamic acids and flavonoids, already reported in the literature as antiglycative and antioxidant agents.