bluuebunny/crossref_metadata_2025 huggingface dataset:
Cobac Control Measures On The Performance Of Mfis
Authors: Felix Dr. Nkiendem , Roland N. Gahmuti , Ayenika Felix Nyuysemo , Sylvie Fokeng , Asah Nchitu Polycarpe
Published: October 2018

Globally, the emergence of MFIS presents an unprecedented opportunity to extend financial services to the vast majority of the population. In Cameroon, MFIs and banks are governed by a series of enactments (conventions, laws, ordinance, presidential decrees, ministerial orders and circulars). Cobac control measures are becoming increasingly important to the performance of microfinance institutions in Cameroon. This measures seems to be indispensible for customer satisfaction as a measure of performance. We therefore set out to verify the level to which these measures influence the performance of microfinancial institutions. Data was collected from 160 respondents in the northwest and littoral regions in Cameroon. Measures of dispersion were studied including inferential statistics in terms of person correlation, test of hypothesis, analysis of variance, chi square. Our results show that COBAC control measures positively influence the performance of MFIs. Thus MFIs should re-enforce the implementation of COBAC control measures instead of considering them as threats
Investment Decisions And The Parallel Funding Routes: Informal savings as a new tool of funding decision in the Cameroonian SMEs
Authors: BEYINA Emmanuel
Published: October 2018

The criteria of the choice of investment elaborated by theoricians are based on rationality of deciders who after some work often consider two types of aids to investment decision: delay of getting back invested capital and net actualized value. Whereas other forms of aid to funding decision exist. We are proposing in the framework of this article, a new model of aid to funding decision corresponding to the new informal funding. We think that risk capital in the framework of informal funding (Ndjangi) can bring forth long-term funding as strategy, and solutions to questions of rationality of the heads of Small and Medium size Enterprise (SMEs) that prefers the delay of getting back invested capital, solutions to problems of decision of choice, and at last solutions to the quality of profitability of investments.
Teachers' Attitude Toward Mathematics Classroom Discourse In Secondary Schools In Kenya
Authors: Jackson Mwelese , Aurah Dr. Catherine , Wanjala Dr. Martin
Published: October 2018

This study was designed to investigate the teachers’ attitude towards classroom discourse and how their attitude is associated with their classroom instructional practices. Their attitude was characterized by their conceptions about the nature of mathematics and their views about classroom discourse in the face of current reforms in mathematics. Mixed method research design was adopted.  The study was based on theoretical frameworks of Vygotsky (1978) and Bruner (1986). The study was conducted in secondary schools in Vihiga County, Kenya. Proportionate stratified and simple random sampling techniques were used to select the sample. Data was collected using questionnaires, interview schedule and classroom observation checklist. Both descriptive and inferential statistics were used to analyze the data. The results of this study show that teachers in the control set ups tend to hold strong conceptions about mathematics that are consistent with the instrumental view. Their conceptions were not in line with the recommended reform approaches and have both desirable and undesirable consequences in the way teachers teach in the classroom.  In view of the findings, it was recommended that in-order to gradually challenge the teachers’ negative conceptions about mathematical classroom discourse, adequate educational interventions should be planned and implemented in teacher education programmes to support the teachers in concretizing these conceptions.
Linguistic reflections of children’s transformation from Circadian to Newtonian time and the direction of time
Authors: OZCAN Mehmet
Published: October 2018

Both linguistically and conceptually, the acquisition of time by children is pretty late when the process is compared with the acquisition and usage of linguistic elements denoting objects, states, actions and situations. This study investigated how children transform their Circadian time to Bergsonian time and how they encode Newtonian time linguistically.

The study was carried out by the researcher’s longitudinal observation of his three daughters from the ages 2 to 10.  In order to verify the idiosyncratic temporal production of the three children, cross-sectional data were also collected using a day organization test.

The results show that, (a) children between the ages of 3 and 4 live more in deictic time in that they refer to momentarily completed events such as a parent’s or sibling’s coming home or doing something which is worth mentioning from point of view of the child (“Baba geldi” ‘Daddy is home.’ or “düştü” ‘(it) fell’). (b) Children live in the Circadian time until the ages of 8-11 in that they conceive of and state time with reference to zeitgebers such as sleep-wake or day-night cycles. They also live simultaneously in Bergsonian time in that they refer to temporal units (e.g. days) with reference to the closest temporal unit (e.g. Dünden sonra” ‘The day dfter yesterday’ to mean the day before yesterday and “Yarından sonra” ‘The day after tomorrow’. (d) They begin to adopt Newtonian time with reference to certain successive events such as “Two days earlier” and then refine their conceptualization of Newtonian time by referring to hours (but not minutes).  (e) Children are pretty ahead of Newtonian time in the construction of complex temporal relations linguistically.
Complexity Leadership Theory and its contribution to decentralized water management analysis and practice
Authors: Nyoni Myengwa Joshua Madida
Published: October 2018

Water management systems in the world have evolved considreably in the last three decades from the traditional "prediction and control"(Phl-Wostl, 2006. p49) approach to more integrative approaches.(Biswas,2004,@004, p24). Practioners in the discipline may find inspiration from a number of leadership approaches in the literature that include transformational, intgrative, collabroative and entrepreneurial leadership, inter alia(Meijerink, S.2011). Another recent and interesting addition to leaadership  literature is found in Complexity Leadership Theory(CLT) as developed by UHl-Bien, Marion and Bill McKelvey(@007). It is premised on on seeking understanding on how organisations respond to pressures in the modern knowledge era, in the contemporary and current work environment as well as in evolving circumstances. The model draws from complexity science, which is the " study of the behaviour of large collections of ....simple, interacting units endowed with the potential to evolve with time"(Coveney, 2003, p.1058 cited in Uhl-Bien et al 2007, p.299). In this respect the central tenet behind Complexity leadership theory is the use of the concept of  complex adaptive systems(CAS) where issues of leadership , which is understood as the capacity to influence others, are seen as not as positions of authority but roles, are entangled between members of an organisation and "can be enacted within everyinteraction between members"(Lichenstein and Plowman 2009, p.618). In unpacking the conceptual framework behind CLT, there a reflection on the dynamic relationship between the bureacratic, administrative functions of the organisations and the emergent, informal dynamics of complex adaptive systems(CAS).The current state of water management, given the competing demands of the biosphere and the socio-sphere are amenable to be relooked at using the CLT lens. The concept of adaptive water management of water resources(Pahl-Wostl, 2006,p.49) is reviewed in realtion to CLT.

Key words: complexity theory, complex adaptive systems, creativity, learning and adaptive water management
Implementing Co-Creation And Multiple Intelligence Practices To Transform The Classroom Experience
Authors: Wilson Stefanie D.
Published: October 2018

Co-creating with a diverse population of learners to enhance their educational experience requires apt skills, namely, multiple intelligence practices.  Through the lens of adult learning theories to include multiple intelligences developed by Harvard psychologist Howard Gardner, this empirical research study of a classroom scenario examines the relationship between co-creating and multiple intelligences leadership practices and presents examples of positive effects of co-creating and multiple intelligence practices that have transformed the classroom experience.  This article integrates the broader literature on adult learning theories to include theories of multiple intelligences and generates new research and insight for current and future educators to implement and transform the classroom experience.
The Gap In Meeting The Educational And Support Needs Of Women With Takotsubo Syndrome Compared To Women With An Acute Coronary Syndrome
Authors: Schubert Simone Claire , Kucia Angela , Hofmeyer Anne
Published: October 2018

Background: Takotsubo Syndrome is a condition that causes impairment in cardiac function in the absence of significant causative coronary artery disease. Takotsubo Syndrome is most commonly reported in older women, has identical presenting symptoms to acute coronary syndrome (ACS),but differs in cause, management and outcomes. Ongoing symptoms and recurrence of Takotsubo Syndrome are not uncommon but little support is available for these women.

 

Aims: This study compares (1) educational support and (2) participation rates in outpatient cardiac rehabilitation for women with Takotsubo Syndrome or acute coronary syndrome, and (3) ascertains whether or not they perceived similar benefits from these strategies.

 

Methods: 23 women with Takotsubo Syndrome and 23 age-matched women with acute coronary syndrome were mailed a structured questionnaire based on cardiac rehabilitation (CR) components.

 

Findings: The questionnaire response rate was 48% (n=11) for the Takotsubo Syndrome group and 30% (n=7) for the acute coronary syndrome group.  18% (n=2) of the women with Takotsubo Syndrome and 71% (n=5) of the women with acute coronary syndrome attended cardiac rehabilitation, with all attendees perceiving that it was beneficial in aiding their recovery.  Of the nine women with Takotsubo Syndrome that did not attend cardiac rehabilitation, 67% (n=6) perceived that it would have been helpful in aiding their recovery. Women with Takotsubo Syndrome were less likely to receive educational support about their condition, particularly stress management and participate in CR compared with women with ACS, despite perceiving that elements of CR would have been helpful in aiding their recovery.

 

Conclusions: Women with ACS had higher CR participation rates than those with Takotsubo Syndrome, and were more likely to receive educational support, particularly following hospital discharge.  The majority of women with Takotsubo Syndrome were not exposed to educational support in their recovery, suggesting a role for CR tailored to the needs of these women. Nurses can take practical steps to address these gaps by providing emotional support and education for women with Takotsubo Syndrome in stress management to enhance their quality of life and reduce potential recurrence.
Developing High Quality Teachers Through Professional Pre-Service Teaching Opportunities
Authors: Walsh Nichole , Akhavan Nancy
Published: October 2018

Based on the reform movements over the past two decades, it is evident that while effective teachers are critical to student learning, not all teachers are coming to the profession highly qualified. Policy and research continue to highlight the need to reorganize and refocus teacher preparation programs to produce higher quality teachers ready to meet the demands of the classroom from day one of employment. This study focuses on the enhancement of traditional preparation programs in public Institutions of Higher Education (IHEs) as this continues to be the context for which most teacher candidates come to the profession. Using a six-group, four measure mixed-methods design, the objective of the study is to determine the impact California Teaching Fellows Foundation (CTFF), a pre-service teaching and learning opportunity for future teacher candidates, has on developing higher caliber teachers prepared in a traditional University-based teacher preparation setting. Through the use of an online survey, interviews, and focus groups, the relationship of CTFF participation to teacher efficacy before, during, and after traditional preparation participation is examined and explored from the perspective of teacher and supervisor. Unexpected findings show that CTFF participation has a relationship to decreased Teacher Efficacy for teacher candidates and CTFF is not creating a significant pipeline to teaching as proposed, leading to questions for further study.
Developments In Stem Educators’ Preparedness For English Language Learners In The United States
Authors: Besterman Keith R , Ernst Jeremy , Williams Thomas O.
Published: October 2018

In the United States, the population of students classified as English Language Learners (ELLs) in K-12 education has increased in recent decades. As a result, teachers outside of specialized linguistic courses have needed to adapt their instruction to better meet the needs of these students. This exploratory study investigates potential indicators of Science, Technology, Engineering, and Mathematics (STEM) teachers’ preparedness to work with ELLs, in comparison with the rates of ELLs in STEM courses.

 

Data for this study were obtained from the national restricted-access datasets of the 2007-2008 and 2011-2012 School and Staffing Survey (SASS) Teacher Questionnaire (TQ). STEM teachers’ participation in ELL-focused professional development activities, credentialing related to ELLs, and ELL populations in STEM teachers’ courses were analyzed to quantify changes in these measures over time and among the STEM disciplines. Regional analysis of STEM teacher populations and ELL populations in STEM classes was also conducted to examine how these factors differed across the United States.

 

Analyses of these data indicated increases in the percentage of STEM teachers who have ELLs in their service loads and in the average number of ELLs in teacher service loads; these trends were present in all U.S. regions and in all STEM disciplines. However, the total number of STEM teachers who participated in ELL-focused professional development activities increased only slightly over the four-year span. To effectively teach the growing ELL student population, STEM teachers must develop the skills and approaches necessary to educate and engage these students.
Calidad técnica y percibida del servicio de operatoria dental en una clínica dental docente
Authors: Manrique-Guzmán Jorge A. , Manrique-Chávez Carolina B. , Chávez-Reátegui Beatriz del C. , Manrique-Chávez Jorge E.
Published: October 2018

Objetivos: Evaluar la calidad técnica de los tratamientos realizados por los operadores y la calidad percibida por los pacientes del Servicio de Operatoria Dental en una Clínica Dental Docente durante el año 2014.  Material y métodos: Participaron 216 pacientes de manera voluntaria y aleatoria a quienes se les aplicó una encuesta para medir la calidad percibida del servicio. Posteriormente, se evaluaron los tratamientos de operatoria que les fueron realizados para determinar la calidad técnica a través de la comparación con los protocolos de atención. Resultados: En relación con la calidad percibida, el 74,8% de los participantes percibe la calidad de atención como “Regular”, seguido de un 15,3% de pacientes que la perciben como “Malo” y un solo un 5% como “Muy malo”. Sólo un 4,3% la percibe como “Bueno” y un 0,6% la percibe como “Muy bueno”. En relación con la cali- dad técnica, se cumple en el 99% de los tratamientos evaluados, ya que se encuentran adheridos a los protocolos de atención clínica. Conclusiones: La calidad percibida por el paciente es en su mayoría negativa o neutral, sin embargo, los resultados de la calidad técnica de los tratamientos describen que éstos se encuentran altamente adheridos a los protocolos de atención.
Control imagenológico de un quiste óseo simple: reporte de un caso
Authors: Cruz Sánchez Rosa Elizabeth , Calderón Ubaqui Víctor , Trevejo Bocanegra Ana Paola , Mercado Portal Nelson Edilbrando
Published: October 2018

El quiste óseo simple (QOS), es considerado un pseudoquiste por no tener tejido de revestimiento epitelial. Esta lesión es más frecuente en pacientes de sexo masculino afectando mayormente el maxilar inferior, comprometiendo la zona posterior mandibular con mayor frecuencia y también la zona sinfisiaria. Algunos autores lo han relacionado a  trauma o degeneración quística dejando una cavidad ósea vacía. Su diagnóstico suele ser por hallazgo radiológico, presentándose como una imagen radiolúcida unilocular o multilocular bien definida o irregular, de bordes corticalizados finos. Su característica principal es el festoneado circundante a las raíces de las piezas dentarias. En este artículo presentamos a un paciente  de sexo masculino de 21 años, al cual le detec- taron incidentalmente a través de la radiografía panorámica una lesión quística. Luego de 2 años de seguimiento imagenológico, se evidenció  la disminución de la lesión.
Model Polya Dalam Peningkatan Hasil Belajar Matematika Pada Pembelajaran Soal Cerita Volume Di Sekolah Dasar
Authors: Ariani Yetti , Kenedi Ary Kiswanto
Published: October 2018

Penelitian ini bertujuan untuk meningkatkan hasil belajar matematika siswa sekolah dasar pada materi soal cerita volume dengan menggunakan model pembelajaran Polya. Metode penelitian adalah penelitian tindakan kelas yang terdiri dari perencanaan, pelaksanan, pengamatan dan refleksi. Instrumen yang dipakai berupa lembar observasi dan soal. Hasil penelitian ini adalah 1) Pada siklus I rencana pelaksanaan pembelajaran mendapatkan skor 62% dengan kategori kurang namun mengalami kenaikan pada siklus II dengan mendapatkan skor sebesar 86% dengan kategori baik, 2) Pengamatan pada aktivitas guru siklus I mendapatkan persentase skor 62% kategori kurang dan meningkat pada siklus II dengan persentase skor adalah 95% dengan kategori sangat baik, 3) Pengamatan pada aktivitas siswa siklus I mendapatkan persentase skor 52% dengan ketegori sangat kategori kurang siklus II meningkat dengan persentase skor 98% dengan ketagori sangat baik, 3) Pengamatan pada aspek hasil belajar mengalami peningkatan yaitu pada siklus I mendapatkan persentase skor yaitu 54,61% dengan kategori sangat kurang dan pada siklus II mendapatkan skor sebesar 85% dengan kategori baik. Dari hal ini disimpulkan bahwa terjadinya peningkatan dalam keempat aspek yaitu aspek RPP, guru, siswa dan hasil belajar. Penelitian ini memiliki implikasi bahwa model Polya cocok digunakan pada pembelajaran soal cerita di sekolah dasar.
Studi Respon Siswa SMP Terhadap Levels Of Inquiry Model Pada Pembelajaran IPA
Authors: Novia Novia , Riandi Riandi , Novianawati Noor
Published: October 2018

Penelitian ini bertujuan untuk mendeskripsikan respon siswa terhadap pembelajaran levels of inquiry model pada pembelajaran IPA secara keseluruhan dan berdasarkan setiap aspeknya. Terdapat sembilan aspek yang terkait dengan respon siswa pada terhadap Levels of Inquiry Model. Selain itu, penelitian ini bertujuan untuk memperoleh gambaran informasi mengenai subjek penelitian. Respon siswa diukur mengunakan Skala Guttman dengan jumlah pertanyaan sebanyak 9 soal. Selain menggunakan kuesioner, penelitian ini juga menggunakan instrumen wawancara terstruktur. Metode penelitian yang dipilih dalam penelitian ini adalah metode deskriptif kuantitatif. Populasi dalam peneitian ini adalah seluruh siswa SMP kelas VII tahun ajaran 2014/2015 di SMP Laboratorium Percontohan UPI Bandung. Sampel dari penelitian ini adalah salah satu kelas VII yaitu kelas VII C. Metode pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling. Hasil penelitian menunjukkan bahwa secara kuantitatif dapat dikatakan bahwa hampir semua siswa (86,7%)  menyukai pembelajaran yang dilakukan dengan model levels of inquiry dengan berbagai alasan, seperti dapat lebih aktif belajar, menyenangkan, lebih memahami materi yang disajikan, menemukan konsep sendiri dan menjadi lebih bersemangat. Hal ini menunjukkan bahwa siswa siap belajar karena telah biasa melakukan pembelajaran levels of inquiry dan memiliki motivasi yang tinggi untuk melaksanakan pembelajarannya.
Keterampilan Berpikir Kritis IPA Siswa SD: Brain Based Learning (BBL) dan Problem Based Learning (PBL)
Authors: Kumala Farida Nur , Firdayani Karvita , Hudha Muhammad Nur
Published: October 2018

Penelitian ini bertujuan untuk mengetahui kemampuan berpikir kritis siswa yang menggunakan model pembelajaran BBL dan PBL. Subyek penelitian ini adalah siswa kelas V SD sejumlah 56 siswa dengan instrumen yang digunakan adalah tes keterampilan berpikir kritis dengan analisis data menggunakan uji-t. Hasil penelitian menunjukkan bahwa keterampilan berpikir IPA siswa yang menggunakan model pembelajaran BBL lebih tinggi daripada yang menggunakan model PBL ditunjukkan dengan nilai rata rata 83 untuk model pembelajaran BBL dan 69 untuk moddel pembelajaran PBL ditunjukkan dengan nilai t hitung > t tabel (5,139>2,003) dan taraf signifikasi 0,000 yang nilainya lebih besar dari 0,05 (0,000<0,05) (sig 0,05). BBL menyediakan pembelajaran yang membuat lebih rileks yang dipadukan dengan kegiatan pembelajaran berbasis masalah, ketika pembelajaran dilakukan secara rileks, penuh arti dan secara aktif  maka otak akan bekerja lebih optimal sehingga siswa merasa lebih nyaman dan termotivasi di kelas.
Mendidik Warga Negara Indonesia Di Sekolah Dasar: Perspektif Guru
Authors: Abdillah Fauzi
Published: October 2018

Penelitian ini berangkat dari kebutuhan data kontekstual mengenai sejauh mana pelaksanaan pembelajaran PPKn, perspektif guru pada materi PPKn dan prospek pengembangan materi PPKn pada tingkat sekolah dasar berdasarkan revisi kurikulum 2013 pada tahun 2016. Data tersebut dibutuhkan dalam rangka pengembangan konten materi perkuliahan di tingkat pendidikan sarjana, khususnya bagi program studi PGSD. Penelitian ini dilaksanakan dengan pendekatan kualitatif melalui metodologi penelitian Grounded theory, penelitian ini menelusuri, memetakan dan menganalisis data terkait materi PPKn SD, khususnya persepsi dan implementasi pembelajaran guru yang mengacu pada materi PPKn di tingkat Sekolah Dasar. Hasil penelitian memberi gambaran mengenai perspektif guru terhadap konten materi PPKn di Kurikulum Nasional revisi 2016, ini sebagai media dan strategi paling relevan untuk meningkatkan kesadaran siswa terhadap nilai, moral, kecakapan hidup bermasyarakat nantinya. Sehingga, rekomendasi untuk konten materi perkuliahan ke-PKn-an di PGSD juga harus berorientasi pada pemenuhan akan pendalaman pada ketiga hal tersebut.
E-Rubric Kerja Ilmiah dengan Menggunakan Model Pembelajaran Inkuiri Terhadap Efektifitas Proses Pembelajaran
Authors: Hudha Muhammad Nur , Aji Sudi Dul , Wolla Baga Yohana Susana , Hakim Arief Rahman
Published: October 2018

Rubrik merupakan suatu perangkat penilaian yang cocok digunakan dalam penilaian bertingkat dan bertahap. Pengembangan e-rubric kerja ilmiah dengan menggunakan model inkuiri sangat cocok untuk mengatasi efisiensi proses penilaian kerja ilmiah siswa. Penelitian ini merupakan jenis penelitian deskriptif. Instrumen yang digunakan dalam penelitian ini adalah menggunakan observasi, wawancara, dan angket. Hasil dari penelitian ini adalah pembelajaran menggunakan model pembelajaran inkuiri berbantuan aplikasi e-rubric sangat efektif dalam menilai kerja ilmiah siswa selama proses pembelajaran berlangsung.
Pengembangan Media Interaktif Berbasis Ispring Materi Sistem Pencernaan Manusia Kelas V Di SDN Ciptomulyo 3 Kota Malang
Authors: Yuniasih Nury , Aini Ririn Nur , Widowati Retno
Published: October 2018

Perkembangan teknologi yang semakin mempengaruhi tingkah laku manusia, mulai dari cara berkomunikasi hingga cara mengajar di kelas. Realitanya masih banyak guru yang kesulitan menggunakan teknologi, menjadikan pembelajaran kurang dapat mengkonkretkan materi. Tujuan dari penelitian ini adalah 1) mengembangkan media interaktif berasis Ispring, 2) mendeskripsikan kelayakan dari media interaktif berbasis Ispring, 3) mendeskripsikan kepraktisan media interaktif berbasis Ispring. Metode yang digunakan mengadaptasi dari model ADDIE dengan empat tahapan yaitu: analisis, desain, pengembangan dan implementasi. Subjek uji coba adalah siswa kelas V SDN Ciptomulyo 3. Instrumen pengumpulan data menggunakan angket, wawancara tidak terstruktur, dan dokumentasi.  Hasil penelitian menunjukkan bahwa media interaktif layak untuk digunakan. Penilaian oleh ahli media mendapatkan presentase 85%. Penilaian oleh ahli materi mendapatkan presentase 94%. Penilaian oleh calon pengguna mendapatkan presentase 93%. Penilaian hasil respon siswa pada ujicoba lapangan terbatas mendapatkan presentase 93%. Berdasarkan paparan hasil penilaian tersebut, media interaktif “Layak” atau “Sangat Baik” untuk digunakan sebagai media pembelajaran.
Preterm Infant with Congenital Tracheal Diverticulum in the Presence of Esophageal Atresia and Tracheoesophageal Fistula
Authors: Glover Williams Alessandra , McNally Janet , Gaskin Julian , Chakkarapani Ela
Published: October 2018

A 32+4-week-preterm neonate was operated on day 1 for esophageal atresia with tracheoesophageal fistula with a tight primary anastomosis and closure of a tracheoesophageal fistula. Postoperatively, he needed ventilation for 6 days. Post-extubation, he needed continuous positive airway pressure support for increased work of breathing, increasing oxygen requirement, and respiratory acidosis when respiratory support was weaned. Further, during the post-operative period, he had right hemidiaphragmatic paresis and acute lifethreatening events requiring manual high-pressure, non-invasive positive pressure ventilation resuscitation. These complications were considered, and a computed tomography assisted by three-dimensional reconstruction was performed. This revealed a congenital tracheal diverticulum and severe tracheomalacia which was confirmed with microlaryngoscopy and bronchoscopy. The presentation and the diagnostic dilemma surrounding this rare diagnosis are discussed in this case report.
A Rare Association of Small Bowel Atresia and In-Utero Midgut Volvulus Presenting as Fetal Meconium Pseudocyst
Authors: Tan Jih Huei , Tan Henry Chor Lip , Ng Zi Qin , Ramli Najua , A/P Vellusamy V Muthualhagi
Published: October 2018

Fetal meconium peritonitis (MP) is a rare occurrence. Neonate that survives this rare condition is likely to form a meconium pseudocyst. Hereby, we present a case of a 33-year-old pregnant woman that presented with premature rupture of membranes at 34 weeks of gestation. Antenatal ultrasonography at 33 weeks revealed abnormal dilated bowel within the viable fetus. An emergency Cesarean section was performed and a baby boy was delivered at 34 weeks. Physical examination of the baby at birth revealed a palpable central abdominal mass. Lower gastrointestinal contrast imaging revealed a non-opacified dilated proximal small bowel and opacified collapsed distal small bowels and colon. A laparotomy was carried out and revealed MP with pseudocyst formation due to a midgut volvulus. Interestingly, meconium contamination was confined due to associated atretic small bowel which occurred secondary to the volvulus.
Mesenteric Lymphangioma with Intestinal Malrotation in a Neonate: A Rare Finding
Authors: Kumar Parveen , Sengar Mamta
Published: October 2018

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Moral and Ethical Principles of Education of Future Physicians: the Holy Doctor Giuseppe Moscati – an Example to Follow
Authors: Kaminskyi Vitalii , Hnatiuk Oksana
Published: October 2018

The article deals with the biographical data of the Italian doctor Giuseppe Moscati (1880-1927), who was recognized as a saint. Moral and ethical principles that he was guided in life are an example to follow by future doctors.
Diagnostic and Treatment Approach in Case of Aorta Mesenteric Clamp
Authors: Kobza Ihor , Nesterenko Irena , Nesterenko Volodimir
Published: October 2018

The article presents anatomical and physiological features of the aorta mesenteric clamp. Diagnostic and treatment features of the pathology were analyzed in order to improve operating procedures. Unfortunately, few published literature data are not the result of multicenter randomized research and indicate the fact that consensus on diagnostic algorithms and therapeutic approach is absent.
CURCUMIN BENEFITS AS ANTIOXIDANT, ANTIINFLAMATION AND ANTIAPOPTOSIS AMELIORATE PARACETAMOL TOXICITY
Authors: Jayadi Tejo , Widiasmoko Bowo
Published: October 2018

Background: Paracetamol poisoning due to the use of paracetamol overdose is the most prevalent case of poisoning. Toxic metabolites from paracetamol cause glutathione depletion and lead to hepatic cell death. Curcumin, a polyphenol substrat in Curcuma longa, has been known to ameliorate the toxic effects of paracetamol. The mechanisms have been known are curcumin as antioxidant, anti-inflammatory, and anti-apoptotic. The curcumin protection mechanism against paracetamol poisoning will be discussed.Methods: The journal’s search for the protective effects of curcumin on paracetamol toxicity is derived from PubMed database using keyword curcumin and acetaminophen. Research on experimental animals is as the limits of the study subjects of the journal search.Result: From a search in PubMed database, there are 15 journal titles discussing the effects of curcumin protection against paracetamol toxicity, and 11 journals selected that correspond to the research topic. Of the 11 journals selected, concluded that curcumin was found to prevent worsening of paracetamol toxicity by increasing antioxidant activity and decreasing inflammation and apoptotic.Conclusion: Curcumin has the potential benefit to be used as a medical therapeutic for the prevention and treatment of paracetamol toxicity.
ADHERENCE TO OPIOID THERAPY IN PATIENTS WITH CHRONIC NON-CANCER PAIN ATTENDING A PAIN CLINIC IN MALAYSIA
Authors: Mizher Hussam , Zin Che S , Sani Asween R , Mohamed Abdul Hadi Bin , Ling Tan H , Izat Munira M
Published: October 2018

Objectives: This study examined the adherence to opioid therapy in patients with chronic noncancer pain (CNCP). The prevalence of opioid use and pain scores was also explored.Methods: This cross-sectional study was conducted among patients with noncancer pain attending a pain clinic at a tertiary hospital in Malaysia from August 2016 to February 2017. All patients prescribed with any of the five available opioids (morphine, oxycodone, fentanyl, buprenorphine, and dihydrocodeine) were included in the study, and their medical and prescription records were assessed for further information on opioid use such as the type of opioid, dose, frequency, and duration. The prevalence of opioid use was calculated by dividing the number of opioid users and the total number of patients attending the pain clinic during the study. Adherence was calculated for patients with long-term opioid therapy (>90 days/ year) and measured using the medication possession ratio (MPR). This was derived by sum up the total days covered with medication in the last 365 days; and then divide that by the total days, the medication was prescribed over the same period. A cutoff point of 80% or more was considered as adherence. The pain intensity score was assessed through a numerical scale from 0 (no pain) to 10 (worst possible pain) at four different points (now, on average, least in the last 24 h, and worst in the last 24 h).Results: A total of 555 patients with various noncancer pain conditions attended the pain clinic during the study. The prevalence of opioid use among these patients was 13.5% (n=74/555). Of these, 24.3% (n=18/74) of patients using opioids for long term (>90 days) and were included in the adherence measure. 78% (n=14/18) of these long-term opioid users were adherent to opioid therapy with a reported MPR >80%. 22% (n=4/18) of patients showed nonadherence to opioid therapy with a reported MPR <80%. The mean pain score for both adherent and nonadherent groups was 5/10, and there was no statistical difference between the two groups.Conclusion: The preliminary results of this study demonstrated that the majority of patients with chronic opioid use adhered to their prescribed opioids. The prevalence of opioid use among patients with noncancer pain was low, and the number of patients using opioid for the long term was ~20% which is similar to the finding from the previous study. The future research is required to evaluate the clinical outcomes in patients with CNCP using opioid for long term particularly in nonadherent patients.
TREATMENT OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) SEPSIS WITH COMBINATION OF FOSFOMYCIN AND AMIKACIN IN A PATIENT WITH SCALD-BURN INJURY
Authors: Putra Oki Nugraha , Saputro Iswinarno Doso , F Ana Khusnul
Published: October 2018

Objective: Thus, this case report assesses the efficacy combination of fosfomycin and amikacin in the management of MRSA infection in a burn patient.Case Report: A 31-year-old male was transferred to the burn center for definitive treatment. Initially, the patient was treated with ceftazidime injection as empiric antibiotic one gram three times daily, but the patient became sepsis during the treatment. Blood specimen was taken and Methicilin Resistant Staphylococcus aureus (MRSA) was isolated from this culture. The patient was isolated and based on antibiotic susceptibility, the patient was started on fosfomycin 2 gram IV twice daily for first seven days, and after that fosfomycin was combined with amikacin IV 500 mg once daily. After administration of these antibiotics, a rapid clinical improvement was observed with the patient, leucocytosis did not occur and blood culture was negative. The patient completed a total of 14 days of fosfomycin and 8 days of amikacin therapy.Conclusion: The synergistic combination of fosfomycin with amikacin, may be useful alternative treatment option for sepsis related Methicilin- Resistant Staphylococcus aureus (MRSA) in burn injury. Further research is also needed to clarify effectiveness of fosfomycin and amikacin to treat MRSA infection in burn patient.
EVALUATION OF THE EFFECT OF DIFFERENT CONCENTRATIONS OF ALOE VERA ON INFLAMMATION AND REEPITHELIALIZATION IN DIABETIC ULCERS IN A RAT MODEL
Authors: Sari Yunita , Purnawan Iwan , Sutrisna Eman , Kurniawan Dhadhang Wahyu , Nasruddin Nasruddin
Published: October 2018

Objective: The objective of this research was to evaluate the effect of different concentrations of Aloe vera (AV) on inflammation of diabetic ulcers in a rat model.Methods: The induction of diabetes was conducted by injection of alloxan monohydrate. This study involved four groups, including 0%, 10%, 30%, and inner leaf AV (ILAV) gel groups. Necrotic tissue, wound size, inflammation, and reepithelialization were evaluated. Wound tissue was collected on days 4 and 8. Histological analysis was performed by hematoxylin and eosin staining. Differences in the intensity of inflammation were analyzed using Kruskal–Wallis test followed by Mann–Whitney U-test.Results: On day 13, wounds in gels containing AV were almost completely healed, whereas wounds in the 0% gel group (control) were still covered with necrotic tissue. On day 3, the intensity of inflammation in the 30% and ILAV groups was significantly less when compared to the 10% and control groups. On day 8, inflammation was less significant in the 10%, 30%, and ILAV groups when compared with the control group. Moreover, the intensity of inflammation in the 30% and ILAV groups was significantly less compared to the 10% group. In addition, reepithelialization was more advanced in the 10% and 30% ILAV groups compared with the control group, and reepithelialization was most advanced in the 30% and ILAV groups.Conclusion: Our study indicated that gels containing AV reduced inflammation and improved reepithelialization of diabetic ulcers in a rat model. Therefore, it is highly recommended for clinicians to use AV gels for topical treatment of diabetic ulcers.
ANTIOXIDANT ACTIVITY OF ETHYL ACETATE FRACTION OF MACARANGA TRILOBA LEAVES FROM CENTRAL KALIMANTAN
Authors: Ardhany Syahrida Dian , Mulia Dewi Sari , Rosawanti Pienyani
Published: October 2018

Objective: Macaranga triloba was used by the local for diabetes, antidiabetes have strong relation with antioxidant activity, antioxidants have been shown to prevent the destruction of β-cells by inhibiting the preoxidation chain reaction, plants containing natural antioxidant (like flavonoid and alkaloid) can protect β cell function. So the objective of this study is to investigate antioxidant activity of ethyl acetate fraction of Macaranga triloba leaves and did preliminary phytochemical screening (Alkaloid and Flavonoid).Methods: Macaranga triloba leaves (Mahang damar) were collected from the local areas of Bukit Rawi Central Kalimantan. Macaranga triloba leaves were extracted using maceration methods, followed by fractionation using liquid-liquid extraction methods starting from n-hexane, ethyl acetate, methanol but in this research used ethyl acetate fraction of Macaraga triloba and preliminary phytochemical screening for alkaloid used dragendorff and flavonoid used Pb Acetate. Antioxidant activity test was carried out using 1,1-diphenyl-2-pikrilhidrazil (DPPH) with quercetin as a reference.Results: It was found that ethyl acetate fraction of Macaranga triloba leaves containing positive flavonoid that has been shown by dragendorff methode (brick red sedimen) and positive alkaloid by Pb acetate. The inhibition concentration 50 (IC50) value of ethyl acetate fraction of Macaranga triloba leaves is 56.93 ppmConclusion: Macaranga triloba leaves by preliminary screening of phytochemical containing alkaloid and flavonoid. Antioxidant activity of ethyl acetate fraction with IC50 = 56.93 ppm is weaker than quercetin (IC50 = 4.46 ppm), but still in range value of strong antioxidant activity (50-100 ppm)
ANTI-METALOTOXIC PROPERTIES OF KELAKAI (STENOCHLAENA PALUSTRIS) LEAVES EXTRACT AGAINST CADMIUM-INDUCED LIVER TISSUE DAMAGE
Authors: Biworo Agung , Azizi Nurul Ainun , Padelia Rizki , Raharja Muhammad Andino , Azima Ozanata , Suhartono Eko
Published: October 2018

Objective: The present study was undertaken to investigate the anti-metalotoxic activity of the leaves extract of Stenochlaena palustris (kelakai; S. palsutris) on cadmium (Cd)-induced liver tissue damage.Methods: Liver tissue damage was induced by the administration of cadmium sulfate (CdSO4) at a dose 3 mg/l. Anti-metalotoxic effect of the extracts was determined by assessing the concentration of malondialdehyde (MDA), carbonyl compound (CC), conjugated dienes (CD), and advanced oxidation protein products (AOPPs) induced by Cd with and without the presence of the extract.Results: The results of this present studies showed that treatment with CdSO4 significantly increase the levels of MDA, CC, CD, and AOPPs. The leaves extract of S. palustris significantly decrease the levels of all measured parameter in liver tissue.Conclusion: The present study demonstrated that Cd could induced the liver tissue damage, and the extract of S. palsutris showed the anti-metalotoxic activity to reduce the damage.
NEW MOLECULAR MECHANISM OF CEFTAZIDIME-INDUCED HUMAN RED BLOOD CELL HEMOLYSIS THROUGH THE PHOTOHEMOLYSIS REACTION
Authors: Mashuri Mashuri , Zaini Achmad , Rahmanisa Diana , Alfiannoor Muhammad Rifqi , Sanjaya Muhammad Rosyhan , Suhartono Eko
Published: October 2018

Objective: The present study was undertaken to investigate the photohemolysis reaction through photosensitization reaction by ceftazidime as a photosensitizer in human red blood cell (RBC).Methods: In this present study, human erythrocytes have used a sample. The sample then divided into six groups consisting of Group 1 (T1) served a negative control which consists of erythrocytes and buffers phosphate with pH 6.8; Group 2 (T2) served as a positive control which consists erythrocytes and buffers phosphate with pH 6.8 and exposed to UV-light; and Group 3, 4, 5, and 6 (T3, T4, T5, and T6) served as an experimental group which consists of erythrocytes, buffer phosphate with pH 6.8, ceftazidime with concentration 10%, 20%, 30%, and 40%, respectively, and also exposed to UV-light. UV-light exposure was done in 2 h. After the treatment period, the level of hydrogen peroxide (H2O2), conjugated diene (CD), advanced oxidation protein products (AOPPs), and percentage of RBC hemolysis (RBCH) were measured.Results: The results of this present studies showed that ceftazidime significantly increases the levels of H2O2, CD, AOPPs, and percentage of RBCH during the UV radiation.Conclusion: The present study demonstrated that ceftazidime acts as a photosensitizer and induced the photohemolysis reaction in human RBC. Furthermore, the hemolysis of RBC seems through the protein damage than lipid damage.
SEARCH FOR GLIOMA DIRECT BINDING SITE OF ALKALOID USING PROTEIN-LIGAND ANT SYSTEM®
Authors: Rifai Yusnita
Published: October 2018

Objective: This research aims to know the best affinity and the best chemical conformation of anticancer compounds from alkaloid groups that have closed direction to Glioma-associated oncogene using protein-ligand ant system (PLANTS®). The interaction energy and hydrogen bond are included as evaluated targets.Methods: In this research, 27 ligands with root mean square deviation score at 1.614 Å and cyclopamine as native ligand are used. Meanwhile, staurosporinone acts as gliomas directed-binding-site-internal-control. Each ligand is docked in GLI with Protein Data Bank code 2GLI using two methods, GLI contains water and without water.Results: PLANTS® score for native ligand in the first and the second method is −73.9002 and −73.2700, respectively. Pancracristine, homoharringtonine, and sanguinarine showed PLANTS® score closed to the cyclopamine score result, but their hydrogen bond interaction differed from native ligan interaction. Evodiamine ligand has a good score and hydrogen bond to the same amino acid of protein GLI, which are GLU 175 and THR 173. This result indicated that evodiamine has the same identical mechanism as staurosporinone.Conclusion: The evodiamine is determined to have the same working mechanism as a GLI inhibitor.
CULTURED HAIR FOLLICLE CELLS FOR THE TREATMENT OF VITILIGO
Authors: Sutnut Piyatida , Suvanasuthi Saroj , Viravaidya-pasuwat Kwanchanok
Published: October 2018

Objective: The objective of this study was to develop a method to isolate cells from hair follicles and cultured them in a hydrogel.Methods: Different cell types obtained from hair follicles were investigated and mixed with three formulations of Lutrol® F-127-based hydrogels. The percentages of the cell attachment and viability were observed within 48 h.Results: The results showed that three cell types, including keratinocyte, dermal papilla, and melanocyte cells, were obtained, as shown by the expression of their corresponding genes. All formulations of the hydrogels supported cell attachment and viability. Interestingly, more than 60% cell attachment and viability were found in lutrol hydrogels supplemented with either fetal bovine serum (FBS) or heat-activated human serum.Conclusion: Higher cell attachment and viability were observed when the hair follicle cells were cultured in the hydrogel with FBS than the hydrogel with human serum. However, the lutrol gel formulation with human serum was more appropriate to be used in the future clinical study, as this formulation contained no animal-derived component.
VARIOUS PARAMETERS AFFECTING THE PRODUCTION OF DRIED TAMBAQUI (Colossoma macropomum) FILLET
Authors: NGUYEN PHUOC MINH
Published: October 2018

Tambaqui (Colossoma macropomum) has been considered promising for fish farming in Mekong region. Tambaqui has a high output production in continental fish farming just after shrimp, catfish and tilapia. The industrial production of tambaquis for export markets is expected to increase, requiring the diversification of processed products from this fish. Itâ€™s normally sold in retail fresh or frozen, whole, or gutted. Therefore present study was conducted to identify the effect of salt soaking time, salt concentration, dry temperature and stability of the dried tambaqui filler with prerservation time. Results of present study revealed that best quality of the driedtambaqui fillet could be obtained when dried tambaqui fillet treated with 1.0% salt for 1.5 hoursand dryingÂ  at 60oC to 28% moisture content. This application could preserve the dried tambaqui fillet for 9 months in PA bag without any deterioration.
INVESTIGATING THE EFFECT OF 1% CURCUMIN GEL AND PLACEBO ON PATIENTS WITH PLAQUE PSORIASIS
Authors: REZA YAGHOOBI  , MEHRNAZ SOGHRATI  , NADER PAZYAR  , NAJMEH PARVIN
Published: October 2018

Psoriasis is a common, chronic, and immunogenetic disease resulting from proliferation of keratinocytes that exists in five forms of plaque, guttate, inverse, pustular, and erythrodermic. Itchy skin is one of the most common symptoms of the disease and influences life quality. This study aimed to compare the effect of 1% curcumin gel made by the Center for Pharmaceutical Technologies Development of Jundishapur University in mild to moderate plaque psoriasis in a randomized and double-blind study as an inexpensive biologically active drug with placebo. The methods of data analysis used in this study - include descriptive statistics, mean, standard deviation, minimum and maximum pasi-score, dermatology life quality index (DLQI), and itchy skin index (QOL-Itchy) as well as inferential statistics including paired t-test, chi-square, and Mann-Whithney test. The analysis was performed by statistics consultant. In the intervention group, the average pasiscore before the treatment was 3.1; two weeks after the treatment it was 1.91 and the pasi-score decrease was significant. Also the average pasi-score reduction in this group was 30.46%; 19% of the patients showed weak therapeutic response, 56% showed average therapeutic response, 13% showed good therapeutic response, and 12% showed excellent therapeutic response. In the control group, the average pasi-score before the treatment was 3.17; after the treatment it was 2.75 where no significant difference was observed. The average pasi-score reduction in this group was 20.4% in which 84% of the patients showed weak response, 8% showed average response, and 8% showed excellent response. A comparison was performed between pasi-scores in intervention and control groups before and after the treatment by employing statistical tests. Though no significant difference was observed, the efficiency size showed that prescription of medicine has a modest effect on patients. In the intervention group, the second week after the end of treatment, the average pasi-score was 1.19; its effect was significant compared with the score before the treatment. The average pasi-score in the control group was 2.75; no significant difference was observed compared with the average score before the treatment. These results showed the continuous effect of medicine after the discontinuation of treatment and no recurrence during this period was observed. The results of this study and previous studies show that curcumin can have an important role in the treatment of psoriasis. It is important because curcumin is an inexpensive drug with less side effects than the existing drugs.
Vibration Protection of Mechanical Systems Consisting of Solid And Deformable Bodies
Authors: Safarov Ismail Ibrahimovich , Khudoyberdiyevich Teshaev Muhsin
Published: October 2018

In this  paper active vibration protection of mechanical systems consisting of solid and deformable bodies is considered. To actively control the oscillations of dissipative mechanical systems, a constructive method is used to determine the structure of the reaction forces of servo constraints. As an example, we consider the system with a finite number of degrees of freedom. Numerical results for various harmonic are also given.