bluuebunny/crossref_metadata_2025 huggingface dataset:
Special Observing Period (SOP) Data for the Year of Polar Prediction site Model Intercomparison Project (YOPPsiteMIP)
Authors: Mariani Zen , Morris Sara , Uttal Taneil , Akish Elena , Crawford Robert , Huang Laura , Day Jonathan , Tjernström Johanna , Godøy Øystein , Ferrighi Lara , Hartten Leslie , Holt Jareth , Cox Christopher , O'Connor Ewan , Pirazzini Roberta , Maturilli Marion , Prakash Giri , Mather James , Strong Kimberly , Fogal Pierre , Kustov Vasily , Svensson Gunilla , Gallagher Michael , Vasel Brian
Published: January 2024

Abstract. The rapid changes occurring in the polar regions require an improved understanding of the processes that are driving the changes. At the same time increased human activities, such as marine navigation, resource exploitation, aviation, commercial fishing, and tourism, require reliable and relevant information. One of the primary goals of the World Meteorological Organization’s Year of Polar Prediction (YOPP) Project is to improve the accuracy of numerical weather prediction (NWP) at high latitudes. During YOPP, two Canadian observatories were commissioned and equipped with new ground-based instruments for enhanced meteorological and system process observations that are considered to be “supersites” for addressing YOPP objectives, while other pre-existing supersites in Canada, the United States, Norway, Finland and Russia provided data from ongoing long-term observing programs. Data from these seven supersites were amalgamated and are being used to evaluate NWP systems from several international forecast centers and to perform meteorological process studies with the aim of improving NWP performance in the Polar Regions. In order to increase data useability and station interoperability, novel Merged Observatory Data Files (MODFs) have been created for these seven international supersites over two Special Observing Periods (February to March 2018 and July to September 2018). All observations collected at the seven supersites were compiled into this new standardized NetCDF MODF format, simplifying the process of conducting pan-Arctic NWP verification and process evaluation studies. This paper describes the seven Arctic YOPP supersites, data collection and processing methods, and the novel MODF format and output files, which together comprise the observational contribution to the associated model intercomparison effort, termed YOPP supersite Model Intercomparison Project (YOPPsiteMIP). All YOPPsiteMIP MODFs are publicly accessible via the YOPP Data Portal (Whitehorse: https://doi.org/10.21343/a33e-j150, Iqaluit: https://doi.org/10.21343/yrnf-ck57, Sodankylä: https://doi.org/10.21343/m16p-pq17, Utqiaġvik: https://doi.org/10.21343/a2dx-nq55, Tiksi: https://doi.org/10.21343/5bwn-w881, Ny-Ålesund: https://doi.org/10.21343/y89m-6393, Eureka: https://doi.org/10.21343/r85j-tc61), hosted by MET Norway, with corresponding output from NWP models.
Exploring Long-term Monthly Prediction of Precipitation Isotopes over Southeast Asia: A Comparative Analysis of Machine-Learning Models
Authors: Heydarizad Mojtaba , Zhongfang Liu , Pumijumnong Nathsuda , Minaei Masoud , Salari Pouya , Sori Rogert , Ghalibaf Mohammadabadi Hamid
Published: January 2024

Abstract. Using stable isotope methods is essential for studying tropical hydrology and climatology. The purpose of this research was to investigate the influence of large-scale climate modes (teleconnection indices) and local meteorological parameters on the stable isotope contents in six different stations, including Bangkok, Kuala Lumpur, Jakarta, Kota Bharu, Jayapura, and Singapore in Southeast Asia. To achieve this goal, several machine learning (ML) techniques were employed, such as shallow neural network (SNN), deep neural network (DNN), decision tree (DT), random forest (RF), and extreme gradient boosting (XGBoost). XGBoost demonstrated the highest accuracy across the majority of studied stations, with a R2 = 0.91, VNS=0.90, AIC= 405, BIC=410, and RMSE = 0.76. Additionally, DNN exhibited superior accuracy in specific cases, achieving a R2 = 0.87, VNS=0.87, AIC = 445, BIC = 460, and RMSE = 1.10. Furthermore, a bootstrap analysis was conducted to assess the uncertainty of the simulated data in each station. The results of this analysis demonstrated acceptable accuracy, as the majority of simulated data points fell within the 95 % confidence intervals. Finally, stable isotope contents in precipitation were forecasted for one year using Vector Autoregression (VAR) and ML techniques. This study underscores the efficacy of ML techniques in both simulating and forecasting stable isotope contents with high precision. The inclusion of specific accuracy metrics strengthens the validity of claims in this study and provides a clearer picture of the quantitative outcomes of this research.
Update on the seismogenic potential of the Upper Rhine Graben southern region
Authors: Michel Sylvain , Duverger Clara , Bollinger Laurent , Jara Jorge , Jolivet Romain
Published: January 2024

Abstract. The Upper Rhine Graben (URG), located in France and Germany, is bordered by north–south-trending faults, some of which are considered active, posing a potential threat to the dense population and infrastructures on the Alsace plain. The largest historical earthquake in the region was the M6.5±0.5 Basel earthquake in 1356. Current seismicity (M>2.5 since 1960) is mostly diffuse and located within the graben. We build upon previous seismic hazard studies of the URG by exploring uncertainties in greater detail and revisiting a number of assumptions. We first take into account the limited evidence of neotectonic activity and then explore tectonic scenarios that have not been taken into account previously, exploring uncertainties for Mmax, its recurrence time, the b value, and the moment released aseismically or through aftershocks. Uncertainties in faults' moment deficit rates, on the observed seismic events' magnitude–frequency distribution and on the moment–area scaling law of earthquakes, are also explored. Assuming a purely dip-slip normal faulting mechanism associated with a simplified model with three main faults, Mmax maximum probability is estimated at Mw 6.1. Considering this scenario, there would be a 99 % probability that Mmax is less than 7.3. In contrast, with a strike-slip assumption associated with a four-main-fault model, consistent with recent paleoseismological studies and the present-day stress field, Mmax is estimated at Mw 6.8. Based on this scenario, there would be a 99 % probability that Mmax is less than 7.6.
استخدام النماذج الإلكترونية وأثره في تطوير أداء الموظفين (دراسة تطبيقية على عمادة الموارد البشرية بجامعة نجران)
Authors:   ماجستير إدارة الموارد البشرية التنفيذي، قسم الإدارة العامة، كلية العلـوم الإدارية، جامعة نجران، المملكة العربية السعودية, آل زمانان تركي
Published: January 2024

هدفت هذه الدراسة إلى التعرف على أثر استخدام النماذج الإلكترونية في تطوير أداء الموظفين على عمادة الموارد البشرية بجامعة نجران، وتمثلت أهمية الدراسة في أنها تساعد في رفع مستوى أداء للعاملين مما يختصر عليه الوقت والجهد في جمع وتوزيع وتحليل ومعالجة النماذج التي كانت تستخدم من قبل، وقد دارت مشكلة الدراسة حول قلة خبرة العاملين في التعامل مع التقنيات الإلكترونية الجديدة بشكل مباشر وسلس، حيث كانت أهم فرضياتها هل توجد فروق ذات دلالة إحصائية لأثر استخدام النماذج الإلكترونية على تطوير أداء الموظفين في عمادة الموارد البشرية بجامعة نجران، وقد استخدم الباحث المنهج الوصفي التحليلي في جمع المعلومات وتحليلها، وتمثلت عينة البحث في العينة العشوائية والبالغ عددها (144) من موظفي الجامعة، واُستخدمت الاستبانة كأداة لجمع البيانات وقد توصل البحث إلى عدة نتائج منها: أنه تساعد النماذج الإلكترونية على الحد من الأعباء الإدارية والإجراءات، وترفع من كفاءة العاملين الموجودين، وتوفر البيانات والمعلومات للمستفيدين بصورة فورية، و تساعد على سرعة إنجاز المعاملات، وتقليل مخاطر فقد ملفات العملاء. وأوصى البحث بضرورة عقد ندوات ورش تدريبية للموظفين لتوعيتهم بأهمية تطبيق النماذج الإلكترونية في الأعمال المختلفة وكذلك إدارة وتنظيم الوقت في إدارة المعاملات الإدارية مما يساعد في الحد من الأعباء الإدارية وإجراءاتها، استخدام التكنولوجيا الحديثة لرفع مستوى التنسيق بين الإدارات داخل عمادة الموارد البشرية من أجل زيادة تفعيل استخدام النماذج الإلكترونية بصورة أكثر كفاءة ومرونة لما له من تأثير مباشر رفع أداء الموظفين، العمل على تطوير البنية التحتية التكنولوجية مثل الحواسيب وشبكات الإنترنت بشكل مستمر لما لها من دور تقليل مخاطر فقد ملفات العملاء وتساعد كذلك في حفظ وسرية البيانات عن طريق التطبيقات التقنية المستخدمة مثل النماذج الإلكترونية.
The Influence of Financial Literacy on Financial Management in Small & Medium Enterprises (Case Study on Coffee Shop Management in Bandung City Period 2020 – 2021)
Authors: Novariani Rifa Keisha , Dialysa Fia
Published: January 2024

Introduction/Main Objectives: This study aims to determine how the development of financial literacy and management as well as to determine the effect of financial literacy on basic financial knowledge, savings and credit, investment and insurance on financial management at SMEs in the form of Coffee Shop in Bandung City. Background Problems: Financial literacy is a person's understanding or ability to measure financial concepts and has the ability to manage finances well. Financial literacy is very necessary for SMEs in managing their business finances. Research Methods: The method used is descriptive and verification analysis method with a quantitative approach. The technique of determining the sample using Nonprobability Sampling. Finding/Results: The results of the study found that literacy about basic financial knowledge has a significant effect on SME’s financial management, literacy about savings and credit has a significant effect on SME’s financial management, literacy about Investment has a significant effect on SME’s financial management and literacy about insurance also has a significant effect on SME’s financial management. Conclusion: The more literate on financial knowledge, savings and credit, investment and insurance, the more SME’s financial management increase.
THE MULTIPLE DIMENSIONS OF INTERNATIONAL ENVIRONMENTAL LAWS: A WAY FORWARD FOR POOR NATIONS
Authors: Dr. Zubaida Aziz
Published: January 2024

This research article examines the challenges faced by poor nations in implementing international environmental agreements and identifies ways forward for addressing environmental challenges. The study highlights the limitations of current international environmental laws and their impact on poor nations, including the lack of financial and technological resources, limited institutional capacity, and inadequate political will. The article also explores the role of international environmental laws in promoting sustainable development and environmental protection in poor nations, and assesses their effectiveness in addressing environmental challenges. The study provides recommendations for policymakers, practitioners, and scholars working on international environmental law and sustainable development, including the development of sustainable development goals and strategies, capacity-building, and technology transfer. The need for a more equitable and inclusive approach to sustainable development and international environmental law is emphasized in the paper's conclusion. This approach should give priority to the needs and viewpoints of developing countries and encourage their full involvement in international efforts to address environmental challenges
THE FUTURE OF CAPITAL MARKETS: THE IMPACT OF TECHNOLOGY ON INVESTOR RELATIONS
Authors: Brig. Prof. Dr. Muhammad Amin SI (M)
Published: January 2024

In this article, we explore the impact of technology on investor relations in capital markets. We examine the role of technology in shaping the future of investor relations and the challenges and opportunities that come with it. Our research finds that technology has significantly changed the way investors interact with companies and has created new channels for communication and engagement. We also discuss the implications of technology on investor behavior and the potential risks associated with its increased use. Our findings have important implications for companies, investors, and regulators as they navigate the evolving landscape of investor relations
CHINA, PAKISTAN AND INDIA: A PERILOUS SAGA
Authors: Dr. Syed Muhammad
Published: January 2024

The deadly triangular relationship between India, Pakistan, and China is a ticking time bomb in the heart of Asia, threatening the stability of the region. This strategic triangle is characterized by a complex web of interests, rivalries, and insecurities that have far-reaching implications for the region’s politics, economy, and security. China’s growing influence in the region, particularly its all-weather friendship with Pakistan, has raised concerns in India, which views China’s expanding footprint as a challenge to its own aspirations for regional dominance. This research article will delve into the intricacies of this triangular relationship, analyzing historical events, conspiracies, and the impact of China’s Belt and Road Initiative (BRI) on the region. The paper will examine the economic implications of the China-Pakistan Economic Corridor (CPEC) for India, and explore avenues for peace, reconciliation, and peaceful coexistence between the three nations. Through a comprehensive analysis of the political, economic, and security dynamics at play, this article aims to provide a deeper understanding of the complexities of the India-Pakistan-China triangle and its implications for regional stability. The research will also offer policy recommendations for fostering greater cooperation and stability in the region, and suggest ways to address the challenges posed by this deadly triangle.
COMMUNITY INVOLVEMENT IN SCHOOL EDUCATION
Authors: Dr. Syeda Bushra Hussain Naqvi
Published: January 2024

This study investigates that civic participation has positive influence on success of students and helps to get best results for students, parents and educators. It brings change in learning behavior, ethnicity and societal actions. These requirements have embraced the perception of parent and civic participation in different way including some part of school governance. The reason of this study was to describe the function and influence of community on educational betterment programs and give a clear picture about the role of parents and other community members. Community participation in education is related to the overall culture of the school. Parents play their supportive role in educational activities that helps to improve the learning skills of students. Recommendations for further research in community-school relationships, training and parent teacher association, preparation for teachers, and the provision of more national and local funds to maintain educational improvement efforts are discussed.
ВДОСКОНАЛЕННЯ ДЕРЖАВНОГО ФІНАНСОВОГО КОНТРОЛЮ В ПОДАТКОВІЙ СИСТЕМІ
Authors: Дацій Н.В. , Малахова Т.В.
Published: January 2024

Обґрунтовано сутність фінансового контролю у податковій системі як фінансово-економічної категорії, підсистеми державного фінансового контролю; розкрито його зміст та структуру. Встановлено, що фінансовий контроль у сфері вітчизняного оподаткування (податковий контроль) є важливою ланкою державного фінансового контролю в Україні. Одночасно він виступає складовою процесу управління оподаткуванням і невід'ємною умовою побудови ефективної податкової системи країни. Фінансовий контроль у податковій системі – це система заходів щодо спостереження за дотриманням законності заходів щодо формування податкових надходжень до бюджетів усіх рівнів, розподілу, перерозподілу та використання даних фінансових ресурсів.
За своєю економічною суттю фінансовий контроль у податковій системі - це вартісний контроль, спрямований на перевірку стану та використання коштів. Зрештою в результаті він означає контроль ефективності використання матеріальних, трудових, природних ресурсів, оскільки цей процес опосередковується грошовими відносинами.
Структура фінансового контролю у податковій системі включає внутрішньовідомчу та внутрішньогосподарську складові частини. В першому випадку податковий контроль здійснюють податкова служба. Для такого роду контролю створюються контрольно-ревізійні відділи та групи. У другому випадку контроль ведеться у державних та комунальних підприємствах, майно яких є власністю держави, відповідними спеціальними підрозділами та службами: бухгалтеріями, фінансовими відділами.
Зроблено висновки щодо організаційно-економічного забезпечення державного фінансового контролю податковими органами, а саме: надходження податків та зборів до бюджетної системи країни, модернізації контрольної роботи, застосування кращого досвіду та підвищення їх ефективності з урахуванням застосування передових методів її оцінки.
В основі методології організації діяльності фінансового контролю у податковій системі лежать: системний підхід до вибору контрольних систем заходів, форм та методів контролю; застосування сучасних телекомунікаційних та інформаційних технологій у процесі здійснення контролю, використання процесного підходу в організації перевірочної діяльності, застосування внутрішнього фінансового аудиту та наявність зворотного зв'язку щодо результатів контрольних заходів; використання кваліфікованих кадрів.
Наведено пропозиції щодо пріоритетів удосконалення державного фінансового контролю у податковій системі, науково-методичного забезпечення його функціонування, моделей побудови взаємовідносин між різними структурами, підвищення якості державного регулювання податкового контролю у сучасних умовах.
A COMPREHENSIVE REVIEW OF MICROSCOPICAL CHARACTERS OF POWDER OF BARK OF BUTEA MONOSPERMA
Authors: Alam, Mr. Firoz , Raghav Ms. Shelly
Published: January 2024

This study has performed a thorough histological analysis of Butea monosperma, offering a dependable method for species identification. Microscopic features stand out as a cost-effective and practical means of distinguishing medicinal plants, upholding their importance in both traditional pharmacognosy and modern monographic studies. Notably, the flower, a defining characteristic for plant identification, assumes a critical role in recognizing this particular plant species. While the Ayurvedic pharmacopoeia has already incorporated a monograph on this flower, the extensive microscopic exploration of the flower remains indispensable, especially given its historical significance in traditional medicine.
A COMPREHENSIVE REVIEW OF MICROSCOPICAL CHARACTERS OF POWDER OF STEM OF BUTEA MONOSPERMA
Authors: Chaudhary Mr. Zaid , Raghav Ms. Shelly
Published: January 2024

This research conducted an in-depth histological analysis of Butea monosperma, offering a reliable method for species identification. Microscopic characteristics emerge as a cost-effective and practical way to differentiate medicinal plants, highlighting their importance in traditional pharmacognosy and modern scientific investigations. Particularly, the stems, crucial for identifying this plant species, play a pivotal role in differentiation. Even though the Ayurvedic pharmacopoeia has a monograph on these stems, a thorough microscopic examination remains vital, especially considering their historical significance in traditional medicine.
A COMPREHENSIVE REVIEW OF MICROSCOPICAL CHARACTERS OF TRANSVERSE SECTION OF LEAVES OF TINOSPORA CARDIFOLIA
Authors: Sharma Dr. Satish Kumar , Raghav Ms. Shelly
Published: January 2024

This critical literature review delves into existing studies and scholarly works that explore the microscopy of the transverse section of leaves from Tinospora cordifolia. Drawing insights from a variety of sources, the review meticulously examines the methodologies employed in the analysis of fresh leaves samples, with a particular focus on advancements in microscopy techniques. It offers a comprehensive overview of the anatomical characteristics unveiled through microscopy, encompassing cell structures, trichome features, and any distinctive elements present in Tinospora cordifolia leaves. The primary objective of this review is to synthesize current knowledge, pinpoint gaps in understanding, and propose potential avenues for future research. In doing so, the review aims to enhance our comprehension of the plant's medicinal properties, thereby supporting its utilization in traditional medicine and pharmaceutical development.
TECHNIQUES AND METHODS FOR GLUCOSE ESTIMATION
Authors: Singh Salender , Singh Swarnima
Published: January 2024

The vital origin of liveliness in a human body is Glucose. In an organ system, brain cells and red blood cells are almost whole-body dependent on carbohydrates as the energy source. The production of energy from carbohydrates is 4 kcal per gram. The molecular formula of glucose is C6H12O6 and glucose is sweet in taste. Glucose is the subcategory of carbohydrates and overall, the most abundant monosaccharide, an important fuel for body. When an individual is well fed, the amount of circulating glucose comes mostly from the food eaten and when an individual is there in a fasting condition the two major metabolic cycles- gluconeogenesis and glycogenolysis are accountable for maintaining the glucose concentration.
महात्मा गांधी जी के शिक्षा संबंधी विचार का विश्लेषण
Authors: सिंह गुरुपंच कुबेर
Published: January 2024

प्रस्तुत शोध पत्र महात्मा गाँधी जी के शैक्षिक विचार का विश्लेषण एवं सामाजिक उपयोगिता का विश्लेषण करना है साथ ही इसके विकास योजना मॉडल का क्रियान्वयन कर सभ्य समाज एवं चरित्रवान नागरिक का निर्माण करना है गाँधी जी हमेशा शिक्षा के महत्त्व को गाँव गाँव तक पहुँचाया है और सभी के लिए निःशुल्क एवं आधारभूत शिक्षा उपलब्ध कराना रहा है। गांधीजी के शिक्षा संबंधी विचार वे शिक्षा को मानव के सर्वांगीण विकास का सशक्त माध्यम तानते थे। अतः वर्धा योजना में उन्होंने प्रथम सात वर्षों की शिक्षा को निःशुल्क एवं अनिवार्य किये जाने पर बल दिया था। गांधीजी का यह मानना भी था कि व्यक्ति अपनी मातृभाषा में शिक्षा को अधिक रुचि तथा सहजता के साथ ग्रहण कर सकता है। आधुनिक भारत के निर्माण में महात्मा गाँधी का बहुआयामी योगदान रहा है द्य गाँधी जी की शिक्षा संबंधी विचारधारा उनके नैतिकता तथा स्वाबलंबन संबंधी सिद्धांतो पर आधारित थी। हरिजन पत्रिका तथा वर्धा शिक्षा योजना में निहित उनके विचारो के माध्यम से इसे देखा जा सकता है।
Indigenously modified endoluminal vacuum-assisted closure therapy for post-operative gastrointestinal leaks: Successful case series
Authors:   Medical Gastroenterology, Lokmanya Tilak Municipal Medical College, Mumbai, India, B Kiran
Published: January 2024

Treatment of gastrointestinal perforations and postoperative anastomotic leaks remains a challenge. Endoluminal Vacuum-assisted closure (E-Vac) therapy has positively contributed, in recent years
How to eat to avoid gastric cancer?
Authors:   Bezmialem Vakif University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Istanbul, Turkey, Ilbak Ilayda Betul
Published: January 2024

Deaths caused by gastric cancer are in the third place among deaths caused by cancer today. Gender, family history of gastric cancer
Study on the mechanism of action of “Astragalus-Vespae Nidus” in the treatment of gastric cancer
Authors:   Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu, Nanjing 210029, China, Su Peng
Published: January 2024

To investigate the active ingredients of Astragalus-Vespae Nidus and its mechanism of action on gastric cancer based on the network pharmacology method.
A case of rectal endometriosis misdiagnosed as rectal malignancy on three colonoscopies and biopsies sharing a combined literature review
Authors:   Huzhou Maternity & Child Health Care Hospital, Huzhou 313000, Zhejiang Province, China, Dong Jie
Published: January 2024

Endometriosis involves the intestine, and its clinical manifestations are nonspecific and lack of etiological manifestations. The diagnosis is difficult, which often leads to misdiagnosis. We report a case of endometriosis which was misdiagnosed as intestinal malignant tumor after colonoscopy and three biopsies.
Four horsemen of the apocalypse: Human immunodeficiency virus infection, cytomegalovirus colitis, kaposi’s sarcoma and ulcerative colitis in one patient
Authors:   Faculty of Medicine, Yeditepe University, Bayar Esra
Published: January 2024

Kaposis Sarcoma (KS) is still one of the most common tumor in Human Immunodeficiency Virus (HIV)-infected patients worldwide. KS is a rare, vascular malignancy of endothelial cells caused by Human Herpesvirus-8 (HHV-8). It can be seen less frequently in Ulcerative Colitis (UC) patients receiving immunosuppressive therapy.
A bibliometric analysis of peroral endoscopic myotomy for achalasia: Where have we been and where should we go next?
Authors:   Zigong First Peoples Hospital, 42 Shangyihao Road, Zigong, 643000, Sichuan Province, China, Zhang Han
Published: January 2024

Peroral endoscopic myotomy (POEM), a treatment for achalasia, has experienced more than ten years of development with significant global progress. We conducted a bibliometrics analysis to reveal the publication trend, influential representative and their cooperation, knowledge base, and research hotspots in this field.
Endoscopic features of helicobacter pylori-uninfected gastric malt lymphoma
Authors:   Division of Gastroenterology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japa, Tohata Misako
Published: January 2024

Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade lymphoma that develops in extranodal organs (e.g., gastrointestinal tract, thyroid gland, and lungs) against the background of chronic inflammation. Approximately 80%-90% of gastric MALT lymphomas
Brain Metastasis: Clinical and Biological Approach
Authors:   Food Sciences Research Institute (CIAL) (CSIC-UAM), 28049 Madrid, Spain, Martin Vanesa Sanchez
Published: January 2024

Cancer includes a broad group of diseases that are characterized by the uncontrolled growth of abnormal cells, which can affect any part of the organism, and according to the World Health Organization (WHO), is one of the leading causes of death worldwide.
Methotrexate-Loaded PLGA Nanoparticle: Extended Survival of GBM-Bearing Rats
Authors:   Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran, M Khosravani
Published: January 2024

This research expresses the preparation and investigation of methotrexate-loaded PLGA nanoparticles on Glioblastoma Multiforme (GBM). The nanoparticles were prepared by precipitation method which had a mean diameter of 102±5 nm with a zeta potential of -26±2 mV
Cytotoxicity and Genotoxicity Effects of Intravenous Injection of 50 nm Gold Nanorods (AuNRs) in Dogs
Authors:   Department of Animal Reproduction, Veterinary Research Institute, National Research Center (NRC, Egypt), Egypt, Abdoon Ahmed Sabry S
Published: January 2024

This work was designed to investigate the possible acute and long-term acute toxicity of intravenous (i.v.) injection of 50 nm gold nanorods (AuNRs) in dogs.
Pathological Response and Gene Expression in Rectal Cancer Neoadjuvant Therapy
Authors:   Department of Microbiology and Molecular Genetics, Michigan State University, USA., de Assis Jessica Vieira
Published: January 2024

Rectal Adenocarcinoma (RA) represents more than 90% of rectal tumors, with high global incidence and mortality rates. Treatment includes neoadjuvant therapy
Bibliometric analysis of the relationship between metabolic study and urolithiasis. A key tool in patient management
Authors:   Universidad Industrial de Santander, Bucaramanga, Colombia, Prieto-Angarita Gabriela , Solano Catalina ,   GRC n20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France, Uroclin, Medellín Manuela Jaramillo-Sierra, Melo-Pedroza Valentina ,   Universidad de La Sabana, Bogotá, Colombia, Ascencio-Medina Andrea ,   Universidad El Bosque, Bogotá, Colombia, Traxer Olivier ,   GRC n20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France
Published: January 2024

Objective: Our objective was doing an analysis of available bibliography to understand tendencies in publications regarding the role of metabolic evaluation in the management of urolithiasis. Materials and Methods: A retrospective bibliometric analysis of the available medical literature ranging from the year 2001 to 2022 was performed on the Web of Science platform. The graph analysis was done using Microsoft Excel and the bibliographic mapping analysis was done on the VOSviewer software. Results: A total of 120 references were found in 63 journals, with a decrease in the rate of publications in the last 5 years. The country, journal, and institution with the largest number of manuscripts were the United States, Journal of Urology, and the University of Bonn, respectively. The author with the largest number of publications was Sarica Kemal. The mapping and analysis of the keyword evolution with respect to the timeline centered on the terms: “prevention”, “metabolic risk factors”, “obesity”, “primary hyperoxaluria”, and “medical management”. Conclusion: Metabolic evaluation is a fundamental tool in the overall approach of these patients. Despite the decrease in the rate of research on the association between metabolic evaluation and urolithiasis in recent years, the importance of a complete assessment of these patients from the first symptomatic episode has been demonstrated, as it helps to determine the risk of recurrence of the disease, and to establish a treatment plan focused on prevention. This first bibliometric analysis on metabolic evaluation and urolithiasis depicts the importance of giving continuity to research on the risk factors of urolithiasis that may be modified and treated.
Management of a long segment of bilateral ureteric injury: A combination of Boari flap and ureteroneocystostomy with psoas hitch
Authors:   Division of Urology, Department of Surgery, Udon Thani Hospital, Udon Thani, Thailand, Tubsaeng Praween
Published: January 2024

Iatrogenic ureteric injuries are a relatively common complication of pelvic and gynecological surgeries which, if left untreated, could lead to medical and legal issues. Therefore, reconstruction of the ureter is still regarded as requiring a sophisticated approach which demands a specialist urologist. This case involves a post-hysterectomy and bilateral salpingo-oophorectomy 46-year-old woman who presented with a bilateral ureteric injury. A left Boari flap and right Lich-Gregoir ureteroneocystostomy with psoas hitch was performed for the correction of the bilateral long segment defect.
Use and acceptance of biometric technologies among victims of identity crime and misuse in Australia
Authors: Emami Catherine , Brown Rick , Smith Russell
Published: January 2024

Biometric technologies make use of an individual’s unique biological characteristics to identify them in their dealings with government and business. Common biometrics include fingerprints, iris recognition, voice pattern recognition and facial recognition, among others. There has been a considerable increase in the uptake of biometric technologies by a number of organisations in recent years, as society looks for ways to safeguard personal information from potential misuse. For instance, fingerprint scanning—once the mainstay of forensic policing—is increasingly used as a means of verifying the identity of mobile phone and tablet users. In 2014, the Australian Institute of Criminology conducted an online survey to gain a greater understanding of identity crime and misuse in Australia. The survey also asked a sample of Australian victims of identity crime about their experiences of, and willingness to use, biometric technologies. This paper presents the results of the research, which indicate generally high levels of previous exposure to biometrics. It also presents some unexpected findings concerning those willing to take up biometrics in the future.
Responding to unruly airline passengers: The Australian context
Authors: Goldsmid Susan , Fuller Georgina , Coghlan Sarah , Brown Rick
Published: January 2024

Unruly passenger incidents have received considerable media attention over the past few years. Unruly passengers are those whose demeanour, behaviour or failure to comply with cabin crew directions present a threat to the safety or security of the aircraft and/or those on board. Australian airlines respond to and manage a small but consistent number of unruly passenger incidents every year. Specific strategies implemented by the airlines, the Australian Federal Police and government and regulatory bodies have focused on minimising the occurrence of and risks associated with these incidents. Despite this, unruly passenger incidents continue to occur, with ramifications for the safety and security of the crew, passengers and aircraft. In June 2015, the Australian Institute of Criminology hosted a roundtable to discuss unruly passenger incidents. Participants included Australian airlines, the police, and other government and regulatory agencies involved in aviation security. This paper draws on both international literature and the roundtable discussions to identify issues related to the identification and management of unruly passenger incidents and the minimisation of associated safety and security risks.
Oreilles ethnographiques
Authors: Pecqueux Anthony
Published: January 2024

La traduction en français du texte de deux « films-conférences » de Steven Feld est l’occasion pour Anthony Pecqueux, spécialiste entre autres de la dimension sensible des rapports sociaux, de présenter et de questionner les enjeux méthodologiques de la démarche de ce pionnier de l’anthropologie du sonore. Il explore en effet différentes méthodes d’observation et de collecte des environnements, des productions et des savoirs acoustiques de diverses sociétés, et élabore des formats de restitution de ses enquêtes capables de faire entendre ce qu’il nomme les acoustémologies.
Innovation drives the success of the life sciences
Authors:   NovaBiotics, O'Neil Deborah
Published: January 2024

Innovation is at the heart of the Scottish health and life sciences sector The Life Science Strategy for Scotland sets a target of £8billion turnover by 2025 Scotland has a very connected and collaborative life sciences ecosystem There was a 50% growth in life sciences startups between 2014 and 2018 Scotland has created a number of new facilities to support the sector.
What is a 'science superpower'?
Authors:   Campaign for Science and Engineering, Main Sarah , Reid Graeme ,   University College London
Published: January 2024

Successive Governments have called for higher levels of investment in research and innovation Recently, this has been accompanied by Government aims of the UK becoming a science superpower There is no unambiguous definition of the term ‘science superpower’ Professors Main and Reid have been exploring scenarios for the UK as a science superpower This record of the discussion also includes references to more recent events.
Learning from the insights of others
Authors:   University of Bristol, Gooberman-Hill Rachael
Published: January 2024

Interdisciplinarity has a long history, wide application and needs disciplinary expertise Interdisciplinarity enables researchers to access insights from other disciplines Effective interdisciplinarity requires investment in time and energy Working across disciplines is as valuable as disciplinary focus Practical mechanisms can unlock the potential for interdisciplinarity
An international focus for fundamental research
Authors:   Nuclear Decommissioning Authority, Garbutt Daniel
Published: January 2024

The Foundation Future Leaders programme aims to acquaint early- to mid-career professionals in Government, research and industry with different examples of science and innovation in action. This September, members of the programme had the opportunity to travel to the Centre for European Nuclear Research (CERN) in Geneva, Switzerland. Daniel Garbutt gives his assessment.
Nuclear’s part in a net zero future
Authors:   Department for Business, Energy and Industrial Strategy (BEIS), Monks Paul
Published: January 2024

By 2050, most of the UK’s energy will come from renewable sources Because of its variability, there will need to be a way to load-balance using low carbon energy and storage Nuclear energy can meet that need Nuclear can also provide large quantities of heat for a variety of applications One of the challenges will be ensuring sufficient skilled people and researchers to deliver this agenda
The role of science in delivering international progress
Authors:   Imperial College London, Skea Jim
Published: January 2024

Science plays a crucial role in underpinning intergovernmental action on climate There is still work to be done simplifying and clarifying scientific messages Lifestyle and behaviour are explicitly included in an IPCC report for the first time The consequences of overshoot need to be better addressed A global stocktake of progress towards meeting the Paris Agreement goals, supported by scientific evidence, will be completed in 2023.
Bringing together the Black scientific community
Authors:   Black in Cancer, Bonner Sigourney
Published: January 2024

A key mantra for Black in Cancer is: “You can’t be what you can’t see” The organisation aims to connect Black science researchers across the globe It aims to tackle the problem of racism in science research Supporting Black researchers includes providing funds for them to do their work Black people do not have to leave science in order to pursue their dreams.
To prepare for tomorrow, look at what is already in place today
Authors:   Government Chief Scientific Adviser, Vallance Patrick
Published: January 2024

Climate will be the biggest issue for governments across the globe for the next 40 years COP26 saw a focus on innovation Scaling up is a massive challenge We need to look at what is available today to see what can be used at scale in 2050 The challenges do not go away in 2050 and we must be prepared for what comes after.
Ocorrência de Aflatoxinas em amendoim e seus produtos comercializados no estado da Bahia durante o ano de 2002
Authors: Batatinha Maria José M. , Santos Monica M. dos , Botura Mariana B. , Almeida Gisele N. , Domingues Luciana F. , Kowalski Claudia H. , Mallmann Carlos A.
Published: January 2024

Este estudo teve como objetivo avaliar a contaminação por aflatoxinas (B1, B2, G1 e G2 ) em amostras de amendoim comercializadas em alguns municípios do estado da Bahia. Foram analisadas 100 amostras, sendo 33 de amendoim e 67 de produtos a base de amendoim. A coleta das amostras foi realizada aleatoriamente em diferentes estabelecimentos comerciais da cidade de Salvador (75 amostras) e em municípios do estado da Bahia (25 amostras) durante o período de janeiro a outubro de 2002. A extração foi realizada com acetonitrila:água (84:16, v/v), e a quantificação das aflatoxinas procedida pelo método de Cromatografia Líquida de Alta Eficiência (CLAE), empregando detecção por fluorescência. Das 31 amostras de amendoim analisadas, 29 (93,55%) foram positivas, sendo que 17 (54,84%), apresentaram teor de contaminação por B1+ B2+G1+G2 superior a 20 µg/kg. Para as 69 amostras de derivados de amendoim, apenas 6 (8,7%) apresentaram contaminação por aflatoxinas B1+B2+G1+G2 superior ao limite. Os resultados ainda revelaram que 20 (80%) do total de amostras coletadas nos municípios do Estado (25) e 38 (50,7%) das 75 amostras procedentes de Salvador foram positivas. Os resultados ressaltam a necessidade de um controle eficaz dos níveis de aflatoxinas destes produtos na região.
Febre amarela silvestre no estado de São Paulo, Brasil: casos humanos autóctones
Authors: Rocco Iray M. , Katz Gizelda , Tubaki Rosa M.
Published: January 2024

Os autores relatam a ocorrência e os dados resultantes das investigações de casos humanos de Febre Amarela (FA) silvestre no estado de São Paulo. Em 2000, 7 casos suspeitos de FA silvestre foram confirmados, 5 importados de outros Estados e 2 provavelmente autóctones, de áreas localizadas às margens do Rio Grande, à noroeste do estado de São Paulo. Quatro deles evoluiram para óbito. Inquérito sorológico foi realizado em 630 habitantes de 13 municípios ribeirinhos e pesquisa entomológica foi feita nas áreas suspeitas de transmissão autóctone. A confirmação desses casos foi feita por testes sorológicos clássicos, isolamento de vírus e técnicas moleculares. As 7 amostras de soros resultaram positivas em pelo menos uma das técnicas empregadas. Todas as amostras foram reagentes no teste de MAC-ELISA. Obteve-se isolamento de vírus a partir de amostras de soros de 4 pacientes e nenhum isolamento de mosquitos. O inquérito sorológico com 630 soros, mostrou 5,23% de prevalência de anticorpos para o vírus FA. A detecção de 2 casos autóctones no estado de São Paulo confirma a tendência de deslocamento da transmissão da Febre Amarela para o Sul do Brasil. A presença de anticorpos para FA em população de áreas sem transmissão recente, revela risco...
Cultura primária de condrócitos articular humana em monocamada
Authors: Kitadai Fabio T. , Figueiredo Cristina A. , Curti Suely P. , Leme Luis Eugênio G. , Carelli Clara D. R. , Amatuzzi Marco M.
Published: January 2024

O objetivo deste trabalho foi padronizar a metodologia para obtenção de cultura primária de condrócitos de cartilagem hialina articular humana para sua utilização em transplante autólogo. Foram selecionados cinco pacientes do Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (IOT-HC-FMUSP) sem doença degenerativa articular, com indicação de cirurgia artroscópica para correção de afecção do ligamento cruzado anterior do joelho. Os fragmentos de cartilagem articular pesando aproximadamente 300-500 mg foram colocados em placas de Petri contendo meio de Eagle modificado por Dulbecco´s (DMEM) com 40µg/ml de gentamicina. Cada fragmento foi cortado e colocado em 2mg/ml de colagenase diluída em meio DMEM com 10% de soro fetal bovino (SFB). As células foram isoladas e cultivadas em frasco de cultura T25 em meio DMEM suplementado com 10% de SFB. As células aderiram ao frasco de cultura após 24 h e após o 3° dia de cultivo as células apresentavam morfologia elipsóide e estrelada. As culturas foram fixadas e coradas intensamente com azul de toluidina sugerindo que as células iniciaram a síntese de uma nova matriz extracellular. A curva de crescimento mostrou que a razão de crescimento foi em torno do segundo e terceiro...
Resíduos de endosulfan em solo (Latossolo Roxo) cultivado com soja [Glycine max (L.) Merrill]
Authors: Corrêa Célia M. D. , Oliveira Jorge J. do V. , Tornisielo Valdemar L.
Published: January 2024

O emprego dos agrotóxicos na agricultura reduz a perda de alimentos ao combater as pragas, porém os seus resíduos podem contaminar o meio ambiente, principalmente o solo. Este trabalho teve como objetivo avaliar os níveis de resíduos do inseticida endosulfan e seu principal metabólito, sulfato de endosulfan, em solo cultivado com a soja. O experimento com a soja foi conduzido em uma área de 900m2, dividida em três parcelas iguais, destinadas ao controle (sem aplicação do inseticida), ao sistema de manejo integrado de pragas (MIP) e ao sistema convencional, com aplicações de endosulfan nas doses de 437g i.a./ha e 1312g i.a./ha, respectivamente. O endosulfan foi quantificado por cromatografia gasosa com detector de captura de elétrons (63Ni), sete dias e um ano após cada pulverização. Não foi detectado nenhum resíduo do inseticida endosulfan no solo (10-20cm), onde foi cultivada a soja no sistema MIP, dentro do limite de quantificação do método [α-endosulfan (0,005mg/g), β-endosulfan (0,005mg/g) e sulfato de endosulfan (0,1mg/g)]. O resíduo de endosulfan total no solo foi de 0,06mg/g para o MIP na profundidade de 0-10cm e para o sistema  convencional os níveis foram 0,14µg/g (0-10cm) e 0,03µg/g (10-20cm). Após um ano da aplicação de endosulfan, nenhum resíduo foi detectado...
Ocorrência de Salmonella spp em carne de frango comercializada no município de Bauru, SP, Brasil
Authors: Matheus Daniel P. , Rudge Aristides C. , Gomes Sônia M. M.
Published: January 2024

Salmonella spp é um dos patógenos mais comumente relacionados com enfermidades transmitidas por alimentos em humanos e é, freqüentemente, associada com o consumo de aves e produtos derivados, no Brasil e no mundo. Este estudo foi conduzido para avaliar a contaminação de carcaças de frango resfriadas, comercializadas diretamente ao consumidor, no município de Bauru, São Paulo, Brasil. No período de abril de 1996 a agosto de 1999, foram coletadas 102 amostras no comércio varejista para pesquisa de Salmonella spp. Dessas, seis (5,9%) foram positivas para Salmonella e, entre os sorotipos isolados, S. Enteritidis foi o mais freqüente com quatro (66,7%) isolamentos, seguido de um (16,7%) isolamento de S. Ouakam e um (16,7%) de S. Saintpaul. Apesar dos resultados terem demonstrado uma porcentagem de contaminação menor do que a verificada em outras pesquisas, os resultados obtidos para S. Enteritidis são semelhantes ao de pesquisas recentes, reforçando a tendência deste sorotipo configurar um problema de Saúde Pública no município de Bauru, SP.
Ocorrência de ocratoxina A e aflatoxinas em arroz
Authors: Simionato Eliane M. R. S. , Astray Renato M. , Sylos Célia M. de
Published: January 2024

Conhecer as micotoxinas que possam ser encontradas no arroz, alimento básico da população brasileira, é importante para a saúde pública. Aflatoxinas e ocratoxina A foram determinadas pelo método de Soares e Rodriguez-Amaya acrescido de partição para ciclohexano. Os testes de recuperação foram realizados em arroz polido e em arroz integral, artificialmente contaminados com aflatoxina B1 (AFB1), com ocratoxina A (OTA) e, com AFB1 e OTA juntas. Recuperações entre 93 e 104% e entre 87 a 103% foram obtidas para AFB1 em arroz polido e em arroz integral, respectivamente. Para a OTA, as recuperações estavam entre 80 e 105% para o arroz polido e entre 83 e 94% para o arroz integral. Os limites de  quantificação conseguidos para AFB1, AFB2, AFG1e AFG2 foram de 1, 1, 3 e 1 µg/kg para o arroz polido, e de 3, 1, 4 e 3 µg/kg para arroz integral, respectivamente. Para a OTA foi de 4 µg/kg em arroz polido e de 10 µg/kg em arroz integral. Foram analisadas 68 amostras de arroz e não foi encontrada OTA em nenhuma delas. AFB1 foi detectada em duas amostras de arroz polido tipo 1 (2,9%), com teores de 9 e 6 µg/kg. Uma das amostras apresentou...
Testes rápidos utilizados na avaliação da qualidade de óleos e gorduras de fritura
Authors: Lopes Maria do Rosário Vigeta , Jorge Neuza
Published: January 2024

Os objetivos foram determinar os níveis de alteração de 58 amostras de óleos e gorduras utilizadas em processos de fritura de estabelecimentos comerciais, e avaliar a confiabilidade dos seguintes testes rápidos: ensaio de Perevalov, Oil Test, Monitor de Gordura 3M e ensaio de Solubilidade em Acetona-Metanol. Para isto, foram empregados os métodos analíticos de determinação de compostos polares totais e de ácidos graxos livres, e em estudo comparativo com estes métodos, foram aplicados os testes rápidos acima mencionados. O conjunto de reagentes de Oil Test e o Monitor de Gordura 3M foram adquiridos comercialmente e os outros dois foram realizados com reagentes preparados no laboratório. Das 58 amostras analisadas, foram encontrados 20,7% e 15,5% com teores de compostos polares e ácidos graxos livres, respectivamente, superiores aos limites estabelecidos em legislações internacionais para óleos e gorduras de fritura. Já os testes rápidos apresentaram resultados corretos em 67,2% para o ensaio de Perevalov; 87,9% quando utilizado o kit Oil Test; 75,9% para o Monitor de Gordura 3M e 62,1% para o ensaio de Solubilidade, quando comparados com o limite estabelecido para compostos polares totais. O Oil Test foi o que apresentou melhor coeficiente de correlação com o teor de compostos polares...