bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 2 from Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma
Authors: Stutterheim Janine , Ichou Fatima Ait , den Ouden Emmy , Versteeg Rogier , Caron Huib N. , Tytgat Godelieve A.M. , van der Schoot C. Ellen
Published: April 2023

PDF file - 78K
Supplementary Table 1 from Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma
Authors: Stutterheim Janine , Ichou Fatima Ait , den Ouden Emmy , Versteeg Rogier , Caron Huib N. , Tytgat Godelieve A.M. , van der Schoot C. Ellen
Published: April 2023

PDF file - 63K
Supplementary Data from GSK1120212 (JTP-74057) Is an Inhibitor of MEK Activity and Activation with Favorable Pharmacokinetic Properties for Sustained In Vivo Pathway Inhibition
Authors: Gilmartin Aidan G. , Bleam Maureen R. , Groy Arthur , Moss Katherine G. , Minthorn Elisabeth A. , Kulkarni Swarupa G. , Rominger Cynthia M. , Erskine Symon , Fisher Kelly E. , Yang Jingsong , Zappacosta Francesca , Annan Roland , Sutton David , Laquerre Sylvie G.
Published: April 2023

Supplementary Figures S1-S6.
CCR Translation for This Article from A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid Tumors
Authors: Schmidt Marcus , Hellwig Birte , Hammad Seddik , Othman Amnah , Lohr Miriam , Chen Zonglin , Boehm Daniel , Gebhard Susanne , Petry Ilka , Lebrecht Antje , Cadenas Cristina , Marchan Rosemarie , Stewart Joanna D. , Solbach Christine , Holmberg Lars , Edlund Karolina , Kultima Hanna Göransson , Rody Achim , Berglund Anders , Lambe Mats , Isaksson Anders , Botling Johan , Karn Thomas , Müller Volkmar , Gerhold-Ay Aslihan , Cotarelo Christina , Sebastian Martin , Kronenwett Ralf , Bojar Hans , Lehr Hans-Anton , Sahin Ugur , Koelbl Heinz , Gehrmann Mathias , Micke Patrick , Rahnenführer Jörg , Hengstler Jan G.
Published: April 2023

CCR Translation for This Article from A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin κ C as a Compatible Prognostic Marker in Human Solid Tumors
Supplementary Figures 1-4 from CPTH6, a Thiazole Derivative, Induces Histone Hypoacetylation and Apoptosis in Human Leukemia Cells
Authors: Trisciuoglio Daniela , Ragazzoni Ylenia , Pelosi Andrea , Desideri Marianna , Carradori Simone , Gabellini Chiara , Maresca Giovanna , Nescatelli Riccardo , Secci Daniela , Bolasco Adriana , Bizzarri Bruna , Cavaliere Chiara , D'Agnano Igea , Filetici Patrizia , Ricci-Vitiani Lucia , Rizzo Maria Giulia , Del Bufalo Donatella
Published: April 2023

PDF file - 264K
Supplementary Table 1 from The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor Picropodophyllin
Authors: Lemaire Miguel , Fristedt Charlotte , Agarwal Prasoon , Menu Eline , Van Valckenborgh Els , De Bruyne Elke , Österborg Anders , Atadja Peter , Larsson Olle , Axelson Magnus , Van Camp Ben , Jernberg-Wiklund Helena , Vanderkerken Karin
Published: April 2023

XLS file - 34K
Supplementary Figure 1 from Stem Cell Pathways Contribute to Clinical Chemoresistance in Ovarian Cancer
Authors: Steg Adam D. , Bevis Kerri S. , Katre Ashwini A. , Ziebarth Angela , Dobbin Zachary C. , Alvarez Ronald D. , Zhang Kui , Conner Michael , Landen Charles N.
Published: April 2023

PDF file - 189K
Supplementary Table 6D from High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
Authors: Schulte Johannes H. , Bachmann Hagen S. , Brockmeyer Bent , DePreter Katleen , Oberthür André , Ackermann Sandra , Kahlert Yvonne , Pajtler Kristian , Theissen Jessica , Westermann Frank , Vandesompele Jo , Speleman Frank , Berthold Frank , Eggert Angelika , Brors Benedikt , Hero Barbara , Schramm Alexander , Fischer Matthias
Published: April 2023

XLS file - 37K
Supplementary Table 6B from High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
Authors: Schulte Johannes H. , Bachmann Hagen S. , Brockmeyer Bent , DePreter Katleen , Oberthür André , Ackermann Sandra , Kahlert Yvonne , Pajtler Kristian , Theissen Jessica , Westermann Frank , Vandesompele Jo , Speleman Frank , Berthold Frank , Eggert Angelika , Brors Benedikt , Hero Barbara , Schramm Alexander , Fischer Matthias
Published: April 2023

XLS file - 61K
Supplementary Table 2 from Combination of a Novel Gene Expression Signature with a Clinical Nomogram Improves the Prediction of Survival in High-Risk Bladder Cancer
Authors: Riester Markus , Taylor Jennifer M. , Feifer Andrew , Koppie Theresa , Rosenberg Jonathan E. , Downey Robert J. , Bochner Bernard H. , Michor Franziska
Published: April 2023

XLS file - 1.8MB
Supplementary Table 1 from Combination of a Novel Gene Expression Signature with a Clinical Nomogram Improves the Prediction of Survival in High-Risk Bladder Cancer
Authors: Riester Markus , Taylor Jennifer M. , Feifer Andrew , Koppie Theresa , Rosenberg Jonathan E. , Downey Robert J. , Bochner Bernard H. , Michor Franziska
Published: April 2023

XLS file - 52K
Supplementary Information from Combination of a Novel Gene Expression Signature with a Clinical Nomogram Improves the Prediction of Survival in High-Risk Bladder Cancer
Authors: Riester Markus , Taylor Jennifer M. , Feifer Andrew , Koppie Theresa , Rosenberg Jonathan E. , Downey Robert J. , Bochner Bernard H. , Michor Franziska
Published: April 2023

PDF file - 3.2MB
Supplementary Table 1 from Detection of TIMP3 Promoter Hypermethylation in Salivary Rinse as an Independent Predictor of Local Recurrence-Free Survival in Head and Neck Cancer
Authors: Sun Wenyue , Zaboli David , Wang Hao , Liu Yan , Arnaoutakis Demetri , Khan Tanbir , Khan Zubair , Koch Wayne M. , Califano Joseph A.
Published: April 2023

PDF file - 68K, Association of each marker individually with overall survival, adjusted for other patient and clinical characteristics of age, HPV, primary tumor site, pathologic tumor stage, and margin status.
Supplementary Table 2 from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter
Published: April 2023

PDF file - 222K, TP53 mutations.
Supplementary Figure Legend from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter
Published: April 2023

PDF file - 158K
Supplementary Table Legend from LY2109761 Attenuates Radiation-Induced Pulmonary Murine Fibrosis via Reversal of TGF-β and BMP-Associated Proinflammatory and Proangiogenic Signals
Authors: Flechsig Paul , Dadrich Monika , Bickelhaupt Sebastian , Jenne Jürgen , Hauser Kai , Timke Carmen , Peschke Peter , Hahn Eric W. , Gröne Hermann-Josef , Yingling Jonathan , Lahn Michael , Wirkner Ute , Huber Peter E.
Published: April 2023

PDF file, 42KB.
Supplementary Figure 8 from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter
Published: April 2023

PDF file - 3293K, Model of PI3K-mTOR and TP53/p73 pathways in HNSCC.
Supplementary Table 1 from LY2109761 Attenuates Radiation-Induced Pulmonary Murine Fibrosis via Reversal of TGF-β and BMP-Associated Proinflammatory and Proangiogenic Signals
Authors: Flechsig Paul , Dadrich Monika , Bickelhaupt Sebastian , Jenne Jürgen , Hauser Kai , Timke Carmen , Peschke Peter , Hahn Eric W. , Gröne Hermann-Josef , Yingling Jonathan , Lahn Michael , Wirkner Ute , Huber Peter E.
Published: April 2023

PDF file, 37KB, Regulated GO-terms and Genes.
Supplementary Figure 7 from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter
Published: April 2023

PDF file - 820K, Effects on p21 in wt and mtTP53 xenografts.
Supplementary Table 1 from Galectin-1 Promotes Lung Cancer Progression and Chemoresistance by Upregulating p38 MAPK, ERK, and Cyclooxygenase-2
Authors: Chung Ling-Yen , Tang Shye-Jye , Sun Guang-Huan , Chou Teh-Ying , Yeh Tien-Shun , Yu Sung-Liang , Sun Kuang-Hui
Published: April 2023

PDF file, 93KB, Clinicopathologic characteristics of patients with lung cancer included in this study.
Supplementary Figure Legend from Galectin-1 Promotes Lung Cancer Progression and Chemoresistance by Upregulating p38 MAPK, ERK, and Cyclooxygenase-2
Authors: Chung Ling-Yen , Tang Shye-Jye , Sun Guang-Huan , Chou Teh-Ying , Yeh Tien-Shun , Yu Sung-Liang , Sun Kuang-Hui
Published: April 2023

PDF file, 103KB.
CCR Translation for This Article from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter
Published: April 2023

CCR Translation for This Article from PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Supplementary Figure 2 from Galectin-1 Promotes Lung Cancer Progression and Chemoresistance by Upregulating p38 MAPK, ERK, and Cyclooxygenase-2
Authors: Chung Ling-Yen , Tang Shye-Jye , Sun Guang-Huan , Chou Teh-Ying , Yeh Tien-Shun , Yu Sung-Liang , Sun Kuang-Hui
Published: April 2023

PDF file, 132KB, Gal-1 knockdown in LLC-1.
Supplementary Figure S5 from The IL-18 Antagonist IL-18–Binding Protein Is Produced in the Human Ovarian Cancer Microenvironment
Authors: Carbotti Grazia , Barisione Gaia , Orengo Anna Maria , Brizzolara Antonella , Airoldi Irma , Bagnoli Marina , Pinciroli Patrizia , Mezzanzanica Delia , Centurioni Maria Grazia , Fabbi Marina , Ferrini Silvano
Published: April 2023

Supplementary Figure S5 - PDF file 470K, Biological effects of IL-27 on cells isolated from the ascites and on EOC cell lines. A-C: Involvement of IL-27 in IL-18BP expression in EOC cells. IL-18BP secretion is detected by ELISA in culture supernatants following A2774 and SKOV3 EOC cell stimulation with IL-27 (10 to 100 ng/ml for 48 h). The effect of IFN-gamma is shown for comparison (A). IL-27 stimulation (48 hours, at the indicated doses) mediates IL-18BP secretion by A2780 and OVCAR5 EOC cell lines, as detected by ELISA (B). ** P<0.005 at all dose levels versus untreated control. IL-27 up-regulates IL18BP mRNA expression in A2774 and SKOV3 cell lines, as assessed by RT-qPCR (C). D: A 10 minutes treatment with IL-27 (10 ng/ml) induces STAT1 tyrosine phosphorylation in A2774 and SKOV3 cells, as detected by Western blot analysis on cell lysates. Tubulin or beta-actin was used as loading controls. Numbers indicate molecular weight markers in kDa. E: Immunofluorescence and confocal microscopy analysis of constitive and IL-27-induced STAT1 tyrosine phosphorylation in EpCAM-positive and EpCAM-negative cells isolated from EOC ascites (specimen A98). Immunofluorescence was performed incubating 5x105 EOC cells with FITC-labeled anti-EpCAM antibody (Miltenyi). Cells, fixed and permeabilzed with BD Cytofix/Cytoperm solution (BD Pharmingen) were then incubated with rabbit anti-IL-18BP antibody (Epitomics) followed by DyLight 549-conjugated anti-rabbit IgG (Jackson ImmunoResearch Laboratories). PermaFluor (Thermo Scientific)-mounted slides were analyzed by confocal fluorescence microscopy using an Olympus (Olympus Optical) laser-scanning microscope FV500 equipped with an Olympus IX81 inverted microscope. Digital images were acquired through PLAPO 60x objectives, with the Fluoview 4.3b software program. Images were acquired sequentially as single trans-cellular optical sections, archived in TIFF and mounted using Photoshop. Merged images are shown. Bar=50micron. Arrows indicate EpCAM-positive pSTAT1-positive ascites cells, arrowheads indicate EpCAM-negative pSTAT1-positive ascites cells
Supplementary Figure Legend from Sequence Dependence of MEK Inhibitor AZD6244 Combined with Gemcitabine for the Treatment of Biliary Cancer
Authors: Xu Junyao , Knox Jennifer J. , Ibrahimov Emin , Chen Eric , Serra Stefano , Tsao Ming , Cao Pinjiang , Vines Douglass , Green David E. , Metran-Nascente Cristiane , McNamara Mairead G. , Hedley David W.
Published: April 2023

PDF file - 92K
Supplementary Figure 7 from Sequence Dependence of MEK Inhibitor AZD6244 Combined with Gemcitabine for the Treatment of Biliary Cancer
Authors: Xu Junyao , Knox Jennifer J. , Ibrahimov Emin , Chen Eric , Serra Stefano , Tsao Ming , Cao Pinjiang , Vines Douglass , Green David E. , Metran-Nascente Cristiane , McNamara Mairead G. , Hedley David W.
Published: April 2023

PDF file - 42K, Inhibitory effect of sequential treatments with AZD6244 and gemcitabine on tumor growth in vivo
Supplementary Figure 6 from Sequence Dependence of MEK Inhibitor AZD6244 Combined with Gemcitabine for the Treatment of Biliary Cancer
Authors: Xu Junyao , Knox Jennifer J. , Ibrahimov Emin , Chen Eric , Serra Stefano , Tsao Ming , Cao Pinjiang , Vines Douglass , Green David E. , Metran-Nascente Cristiane , McNamara Mairead G. , Hedley David W.
Published: April 2023

PDF file - 94K, Effects of treatments on body weight and white blood cell counts
Supplementary Figure 4 from Iron Deprivation Suppresses Hepatocellular Carcinoma Growth in Experimental Studies
Authors: Ba Qian , Hao Miao , Huang He , Hou Junmei , Ge Shichao , Zhang Zhuzhen , Yin Jun , Chu Ruiai , Jiang Hualiang , Wang Fudi , Chen Kaixian , Liu Hong , Wang Hui
Published: April 2023

PDF file - 1.9MB
Supplementary Figure 3 from Iron Deprivation Suppresses Hepatocellular Carcinoma Growth in Experimental Studies
Authors: Ba Qian , Hao Miao , Huang He , Hou Junmei , Ge Shichao , Zhang Zhuzhen , Yin Jun , Chu Ruiai , Jiang Hualiang , Wang Fudi , Chen Kaixian , Liu Hong , Wang Hui
Published: April 2023

PDF file - 295K
Supplementary Figure 6 from Stichoposide C Induces Apoptosis through the Generation of Ceramide in Leukemia and Colorectal Cancer Cells and Shows In Vivo Antitumor Activity
Authors: Yun Seong-Hoon , Park Eun-Seon , Shin Sung-Won , Na Yong-Woo , Han Jin-Yeong , Jeong Jin-Sook , Shastina Valeria V. , Stonik Valentin A. , Park Joo-In , Kwak Jong-Young
Published: April 2023

PDF file - 1.8MB, Antioxidants inhibit the activation of neutral SMase and BSO enhances the activation of neutral SMase by STC in human leukemic cells. (A to C) HL-60 and K562 cells (1 �~ 105 cells/ well) were incubated with STC in the presence or absence of NAC, catalase, or BSO for 2 h. Following permeabilization, samples were stained with PE-anti-acid SMase (A), PE-anti-neutral SMase (B), or PE-anti-Fas (C) and FITC-anti-ceramide antibodies, respectively.
Supplementary Figure 5 from Stichoposide C Induces Apoptosis through the Generation of Ceramide in Leukemia and Colorectal Cancer Cells and Shows In Vivo Antitumor Activity
Authors: Yun Seong-Hoon , Park Eun-Seon , Shin Sung-Won , Na Yong-Woo , Han Jin-Yeong , Jeong Jin-Sook , Shastina Valeria V. , Stonik Valentin A. , Park Joo-In , Kwak Jong-Young
Published: April 2023

PDF file - 1.8MB, GSH inhibits STC-induced neutral SMase activation, but it does not inhibit activation of Fas and acid SMase by STC in human leukemic and colorectal cancer cells. (A) HL-60 cells were treated with STC (0.3 muM) for 2 h in the presence or absence of GSH. Following permeabilization, samples were stained with PE-anti-acid SMase, PE-anti-neutral SMase, or PE-anti-Fas and FITC-anti-ceramide antibodies, respectively. (B) K562 cells were treated with STC (0.5 muM) for 2 h in the presence or absence of GSH. Following permeabilization, samples were stained with PE-anti-neutral SMase, PE-anti-acid SMase, or PE-anti-Fas and FITC-anti-ceramide antibodies, respectively. (C) SNU-C4 cells were treated with STC for 24 h in the presence or absence of GSH. Following permeabilization, samples were stained with PE-anti-neutral SMase, PE-anti-acid SMase, or PE-anti-Fas and FITC-anti-ceramide antibodies, respectively. (D) In parallel, whole lysates from HL-60 and K562 cells incubated with STC for 6 h in the presence or absence of GSH were prepared and analyzed by Western blot as described. In each case, 30 mug of protein was separated by SDS-PAGE, after which blots were probed with the corresponding antibodies. Blots were subsequently stripped and re-probed with antibodies directed against beta-actin to ensure equivalent loading and transfer.
Supplementary Figure 2 from Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer
Authors: Sen Malabika , Joyce Sonali , Panahandeh Mary , Li Changyou , Thomas Sufi M. , Maxwell Jessica , Wang Lin , Gooding William E. , Johnson Daniel E. , Grandis Jennifer R.
Published: April 2023

PDF file, 216K, Decreased STAT3 target gene expression in erlotinib sensitive (or resistant) HNSCC cells treated with the STAT3 decoy.
Supplementary Figure 3 from Stichoposide C Induces Apoptosis through the Generation of Ceramide in Leukemia and Colorectal Cancer Cells and Shows In Vivo Antitumor Activity
Authors: Yun Seong-Hoon , Park Eun-Seon , Shin Sung-Won , Na Yong-Woo , Han Jin-Yeong , Jeong Jin-Sook , Shastina Valeria V. , Stonik Valentin A. , Park Joo-In , Kwak Jong-Young
Published: April 2023

PDF file - 2.3MB, Activation of acid and neutral SMase by STC is independent from activation of Fas and caspase-8. (A) HL-60 and K562 cells were incubated with STC (0.3 muM or 0.5 muM, respectively) in the presence or absence of desipramine or GW4869 for 2 h and fixed. Following permeabilization, samples were stained with PE-anti-Fas and FITC-anti-ceramide antibodies as described in the Materials and Methods. The picture is representative of 5 separate experiments. Left panel shows the high magnification of HL-60 cells treated as in A. Right panel shows high magnification of K562 cells treated as in A. (B) In parallel, whole lysates from HL-60 and K562 cells incubated with STC for 6 h in the presence or absence of desipramine or GW4869 were prepared and analyzed by Western blot as described. In each case, 30 mug of protein was separated by SDS-PAGE, after which blots were probed with the corresponding antibodies. Blots were subsequently stripped and re-probed with antibodies directed against beta-actin to ensure equivalent loading and transfer. (C) HL-60 and K562 cells were transiently transfected by electroporation with none (shock), nonspecific control (NC) siRNA, siRNA for acid SMase (ASM), or siRNA for neutral SMase (NSM) for 48 h. The culture medium was changed, and cells were treated with or without STC (0.3 muM or 0.5 muM, respectively) for 6 h. Protein lysates were prepared and subjected to Western blot analysis as described in Materials and Methods using corresponding antibodies. Equal protein loading was ensured by demonstrating uniform beta-actin expression. The blot is representative of 5 separate experiments.
Supplementary Figure 1 from Stichoposide C Induces Apoptosis through the Generation of Ceramide in Leukemia and Colorectal Cancer Cells and Shows In Vivo Antitumor Activity
Authors: Yun Seong-Hoon , Park Eun-Seon , Shin Sung-Won , Na Yong-Woo , Han Jin-Yeong , Jeong Jin-Sook , Shastina Valeria V. , Stonik Valentin A. , Park Joo-In , Kwak Jong-Young
Published: April 2023

PDF file - 2MB, Treatment of HL-60 and human primary leukemia cells with STC leads to generation of ceramide through the activation of Fas, acid SMase and neutral SMase. (A) HL-60 cells were treated with STC (0.3 muM) for 2 h and were then fixed. Following permeabilization, samples were stained with PI and FITC-anti-ceramide antibody. Confocal microscopy analysis indicated STC induces accumulation of ceramide. The results are representative of five experiments. TNFalpha was used as a positive control. (B, C, and D) Human primary leukemia cells (1 �~ 105 cells/well) were incubated with STC for 6 h. After treatment, cells were fixed and permeabilized. Then, samples were stained with FITC-ant-ceramide and (B) PE-anti-acid SMase or (C) PE-anti-neutral SMase or (D) PE-anti-Fas antibodies. The upper panel shows the low magnification of human primary leukemia cells treated as in B. The lower panel shows higher magnification of human primary leukemia cells treated as in B.
Supplementary Table 1 from Gene Expression Signature–Based Prognostic Risk Score in Patients with Primary Central Nervous System Lymphoma
Authors: Kawaguchi Atsushi , Iwadate Yasuo , Komohara Yoshihiro , Sano Masakazu , Kajiwara Koji , Yajima Naoki , Tsuchiya Naoto , Homma Jumpei , Aoki Hiroshi , Kobayashi Tsutomu , Sakai Yuko , Hondoh Hiroaki , Fujii Yukihiko , Kakuma Tatsuyuki , Yamanaka Ryuya
Published: April 2023

PDF file, 39K, QPCR data.
Supplementary Figure Legend from Gene Expression Signature–Based Prognostic Risk Score in Patients with Primary Central Nervous System Lymphoma
Authors: Kawaguchi Atsushi , Iwadate Yasuo , Komohara Yoshihiro , Sano Masakazu , Kajiwara Koji , Yajima Naoki , Tsuchiya Naoto , Homma Jumpei , Aoki Hiroshi , Kobayashi Tsutomu , Sakai Yuko , Hondoh Hiroaki , Fujii Yukihiko , Kakuma Tatsuyuki , Yamanaka Ryuya
Published: April 2023

PDF file, 53K.
Related Article from Accelerated Approval and Breakthrough Therapy Designation: Oncology Drug Development on Speed?
Authors: Yao James C. , Meric-Bernstam Funda , Lee J. Jack , Eckhardt S. Gail
Published: April 2023

Related Article from Accelerated Approval and Breakthrough Therapy Designation: Oncology Drug Development on Speed?
Supplementary Figure 1 from Dendritic Cell–Activating Vaccine Adjuvants Differ in the Ability to Elicit Antitumor Immunity Due to an Adjuvant-Specific Induction of Immunosuppressive Cells
Authors: Dang Yushe , Wagner Wolfgang M. , Gad Ekram , Rastetter Lauren , Berger Carmen M. , Holt Gregory E. , Disis Mary L.
Published: April 2023

PDF file, 86KB, The administration of anti-Gr-1 and anti-CD25 mAb can deplete MDSC and Treg cells respectively.
Supplementary Table 1 from Phase II Study of Bevacizumab in Combination with Sorafenib in Recurrent Glioblastoma (N0776): A North Central Cancer Treatment Group Trial
Authors: Galanis Evanthia , Anderson S. Keith , Lafky Jackie M. , Uhm Joon H. , Giannini Caterina , Kumar Shaji K. , Kimlinger Teresa K. , Northfelt Donald W. , Flynn Patrick J. , Jaeckle Kurt A. , Kaufmann Timothy J. , Buckner Jan C.
Published: April 2023

Supplementary Table 1 - PDF file 37K, Most Common (incidence >10%) Grade 3/4 Toxicities per Dose Group
Supplementary Table 2 from Cyclophosphamide Induces a Type I Interferon–Associated Sterile Inflammatory Response Signature in Cancer Patients' Blood Cells: Implications for Cancer Chemoimmunotherapy
Authors: Moschella Federica , Torelli Giovanni Fernando , Valentini Mara , Urbani Francesca , Buccione Carla , Petrucci Maria Teresa , Natalino Fiammetta , Belardelli Filippo , Foà Robin , Proietti Enrico
Published: April 2023

PDF file - 117K, List of the genes up-regulated 1-2 days following CTX treatment.
Supplementary Figure Legend from Cyclophosphamide Induces a Type I Interferon–Associated Sterile Inflammatory Response Signature in Cancer Patients' Blood Cells: Implications for Cancer Chemoimmunotherapy
Authors: Moschella Federica , Torelli Giovanni Fernando , Valentini Mara , Urbani Francesca , Buccione Carla , Petrucci Maria Teresa , Natalino Fiammetta , Belardelli Filippo , Foà Robin , Proietti Enrico
Published: April 2023

PDF file - 67K
Supplementary Figure 2 from Cyclophosphamide Induces a Type I Interferon–Associated Sterile Inflammatory Response Signature in Cancer Patients' Blood Cells: Implications for Cancer Chemoimmunotherapy
Authors: Moschella Federica , Torelli Giovanni Fernando , Valentini Mara , Urbani Francesca , Buccione Carla , Petrucci Maria Teresa , Natalino Fiammetta , Belardelli Filippo , Foà Robin , Proietti Enrico
Published: April 2023

PDF file - 143K, Representative histogram plots.
Supplementary Figure 4 from Universal Cancer Peptide-Based Therapeutic Vaccine Breaks Tolerance against Telomerase and Eradicates Established Tumor
Authors: Dosset Magalie , Godet Yann , Vauchy Charline , Beziaud Laurent , Lone Yu Chun , Sedlik Christine , Liard Christelle , Levionnois Emeline , Clerc Bertrand , Sandoval Federico , Daguindau Etienne , Wain-Hobson Simon , Tartour Eric , Langlade-Demoyen Pierre , Borg Christophe , Adotévi Olivier
Published: April 2023

PDF file - 57K, UCPs mediated helper effect on CTLs in other models of vaccinations
Supplementary Material from Ang-2-VEGF-A CrossMab, a Novel Bispecific Human IgG1 Antibody Blocking VEGF-A and Ang-2 Functions Simultaneously, Mediates Potent Antitumor, Antiangiogenic, and Antimetastatic Efficacy
Authors: Kienast Yvonne , Klein Christian , Scheuer Werner , Raemsch Romi , Lorenzon Erica , Bernicke Dirk , Herting Frank , Yu Sidney , The Huynh Hung , Martarello Laurent , Gassner Christian , Stubenrauch Kay-Gunnar , Munro Kate , Augustin Hellmut G. , Thomas Markus
Published: April 2023

PDF file 108K, Detailed description of experimental procedures
Supplementary Table 1 from Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro
Authors: Kahlert Christoph , Lahes Saleh , Radhakrishnan Praveen , Dutta Shamik , Mogler Carolin , Herpel Esther , Brand Karsten , Steinert Gunnar , Schneider Martin , Mollenhauer Martin , Reissfelder Christoph , Klupp Fee , Fritzmann Johannes , Wunder Christina , Benner Axel , Kloor Matthias , Huth Cathrin , Contin Pietro , Ulrich Alexis , Koch Moritz , Weitz Jürgen
Published: April 2023

PDF file - 55K, Primer sequences used for qRT-PCR.
Supplementary Figure 4 from Ang-2-VEGF-A CrossMab, a Novel Bispecific Human IgG1 Antibody Blocking VEGF-A and Ang-2 Functions Simultaneously, Mediates Potent Antitumor, Antiangiogenic, and Antimetastatic Efficacy
Authors: Kienast Yvonne , Klein Christian , Scheuer Werner , Raemsch Romi , Lorenzon Erica , Bernicke Dirk , Herting Frank , Yu Sidney , The Huynh Hung , Martarello Laurent , Gassner Christian , Stubenrauch Kay-Gunnar , Munro Kate , Augustin Hellmut G. , Thomas Markus
Published: April 2023

PDF file 67K, A2V CrossMab treatment inhibits angiogenesis in the VEGF-induced cornea pocket assay
Supplementary Figure S7 from Leukemia Cell-Rhabdovirus Vaccine: Personalized Immunotherapy for Acute Lymphoblastic Leukemia
Authors: Conrad David P. , Tsang Jovian , Maclean Meaghan , Diallo Jean-Simon , Le Boeuf Fabrice , Lemay Chantal G. , Falls Theresa J. , Parato Kelley A. , Bell John C. , Atkins Harold L.
Published: April 2023

Supplementary Figure S7 - PDF file 1183K, UV-treated apoptotic and pressure-disrupted necrotic L1210 cells used for specific vaccine preparations
Supplementary Figure Legend from Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
Authors: Bloch Orin , Crane Courtney A. , Kaur Rajwant , Safaee Michael , Rutkowski Martin J. , Parsa Andrew T.
Published: April 2023

PDF file - 70K
Supplementary Figure S3 from Leukemia Cell-Rhabdovirus Vaccine: Personalized Immunotherapy for Acute Lymphoblastic Leukemia
Authors: Conrad David P. , Tsang Jovian , Maclean Meaghan , Diallo Jean-Simon , Le Boeuf Fabrice , Lemay Chantal G. , Falls Theresa J. , Parato Kelley A. , Bell John C. , Atkins Harold L.
Published: April 2023

Supplementary Figure S3 - PDF file 612K, iLOV efficacy using VSVd51 virus
Supplementary Figure 1 from Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages
Authors: Bloch Orin , Crane Courtney A. , Kaur Rajwant , Safaee Michael , Rutkowski Martin J. , Parsa Andrew T.
Published: April 2023

PDF file - 22K, Figure S1. Glioma cells induce B7-H1 expression in peripheral monocytes from healthy donors. Monocytes from healthy donors were cultured alone in normal media or in co-culture with U251 glioma cells in contact or through a 0.2μm pore filter. The percentage of B7-H1 expressing cells was determined by flow cytometry. Compared to normal monocytes, cells cultured with glioma cells through a filter (non-contact) have significantly more B7-H1 positive monocytes (* p < 0.005) and cells co-cultured in contact demonstrate a further significant increase in B7-H1 expression (vs. normal, ** p<0.001; vs. non-contact, p<0.01). Columns represent mean percent expression plus-minus SEM from 4 independent samples. Each sample was tested in triplicate and averaged as a single data point.
Supplementary Figure S1 from Leukemia Cell-Rhabdovirus Vaccine: Personalized Immunotherapy for Acute Lymphoblastic Leukemia
Authors: Conrad David P. , Tsang Jovian , Maclean Meaghan , Diallo Jean-Simon , Le Boeuf Fabrice , Lemay Chantal G. , Falls Theresa J. , Parato Kelley A. , Bell John C. , Atkins Harold L.
Published: April 2023

Supplementary Figure S1 - PDF file 21K, Treatment schedules
Supplementary Tables 1 - 2 from miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways
Authors: Majid Shahana , Dar Altaf A. , Saini Sharanjot , Shahryari Varahram , Arora Sumit , Zaman Mohd Saif , Chang Inik , Yamamura Soichiro , Tanaka Yuichiro , Chiyomaru Takeshi , Deng Guoren , Dahiya Rajvir
Published: April 2023

PDF file - 76K, Supplemental Table 1. Clinicopathologic characteristics of prostate cancer patients. Supplemental Table 2. Complimentary sequences in 3'UTRs of genes for miR-34b and sequences of primers and probes.
Supplementary Figure 7 from CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Authors: Deng Yong-Jian , Tang Na , Liu Chao , Zhang Jiang-Yu , An Sheng-Li , Peng Yin-Li , Ma Li-Li , Li Guang-Qiu , Jiang Qiang , Hu Chun-Ting , Wang Ya-Nan , Liang Yao-Ze , Bian Xiu-Wu , Fang Wei-Gang , Ding Yan-Qing
Published: April 2023

PDF file - 45K, Representative images of IHC examination of CLIC4, ERp29 and Smac in CRC tumors and mucosa.
Supplementary Figure 2 from Mutated BCR-ABL Generates Immunogenic T-cell Epitopes in CML Patients
Authors: Cai Ann , Keskin Derin B. , DeLuca David S. , Alonso Anselmo , Zhang Wandi , Zhang Guang Lan , Hammond Naa Norkor , Nardi Valentina , Stone Richard M. , Neuberg Donna , Sidney John , Brusic Vladimir , Wu Catherine J.
Published: April 2023

PDF file, 135K, Analysis of potential peptide binders for common mutations related to dasatinib and nilotinib.
Supplementary Figure 3 from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
Authors: Grassilli Emanuela , Narloch Robert , Federzoni Elena , Ianzano Leonarda , Pisano Fabio , Giovannoni Roberto , Romano Gabriele , Masiero Laura , Leone Biagio Eugenio , Bonin Serena , Donada Marisa , Stanta Giorgio , Helin Kristian , Lavitrano Marialuisa
Published: April 2023

Supplementary Figure 3 - PDF file 33K, GSK3B depletion does not abolish the resistance of HCT116p53KO cells to targeted drugs
Supplementary Figure 2 from Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy
Authors: Grassilli Emanuela , Narloch Robert , Federzoni Elena , Ianzano Leonarda , Pisano Fabio , Giovannoni Roberto , Romano Gabriele , Masiero Laura , Leone Biagio Eugenio , Bonin Serena , Donada Marisa , Stanta Giorgio , Helin Kristian , Lavitrano Marialuisa
Published: April 2023

Supplementary Figure 2 - PDF file 42K, GSK3B silencing by siRNA abolishes drug resistance of p53-null colon carcinoma cell lines
Related Article from Tumor-Specific T-cell Help Is Associated with Improved Survival in Melanoma
Authors: Woods Katherine , Cebon Jonathan
Published: April 2023

Related Article from Tumor-Specific T-cell Help Is Associated with Improved Survival in Melanoma
Supplementary Figure 3 from Overexpression of Ecdysoneless in Pancreatic Cancer and Its Role in Oncogenesis by Regulating Glycolysis
Authors: Dey Parama , Rachagani Satyanarayana , Chakraborty Subhankar , Singh Pankaj K. , Zhao Xiangshan , Gurumurthy Channabasavaiah Basavaraju , Anderson Judy M. , Lele Subodh , Hollingsworth Michael A. , Band Vimla , Batra Surinder K.
Published: April 2023

PDF file - 1974K, In vivo glucose uptake in orthotopic tumors of Capan1 Scr and Capan1 Ecd KD cell injected mice
Supplementary Figure 1 from FANCD2 Is a Potential Therapeutic Target and Biomarker in Alveolar Rhabdomyosarcoma Harboring the PAX3–FOXO1 Fusion Gene
Authors: Singh Mamata , Leasure Justin M. , Chronowski Christopher , Geier Brian , Bondra Kathryn , Duan Wenrui , Hensley Lauren A. , Villalona-Calero Miguel , Li Ning , Vergis Anthony M. , Kurmasheva Raushan T. , Shen Changxian , Woods Gary , Sebastian Nikhil , Fabian Denise , Kaplon Rita , Hammond Sue , Palanichamy Kamalakannan , Chakravarti Arnab , Houghton Peter J.
Published: April 2023

PDF file - 83KB, Skin toxicity scores during radiation treatments.
Supplementary Table 2 from Inhibitors Targeting Mitosis: Tales of How Great Drugs against a Promising Target Were Brought Down by a Flawed Rationale
Authors: Komlodi-Pasztor Edina , Sackett Dan L. , Fojo Antonio Tito
Published: April 2023

PDF file, 89KB, Kinesin Spindle Protein Inhibitors in Clinical Trials.
Supplementary Figure 1 from Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer
Authors: Coffee Erin M. , Faber Anthony C. , Roper Jatin , Sinnamon Mark J. , Goel Gautam , Keung Lily , Wang Wei Vivian , Vecchione Loredana , de Vriendt Veerle , Weinstein Barbara J. , Bronson Roderick T. , Tejpar Sabine , Xavier Ramnik J. , Engelman Jeffrey A. , Martin Eric S. , Hung Kenneth E.
Published: April 2023

Supplementary Figure 1 PDF file 118K, Development a GEMM for BRAFV600E CRC
Supplementary Materials and Methods from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Materials and Methods - PDF file 21K, Antibodies, Inhibitors, and siRNA
Supplementary Figure 4 from Molecular Determinants of Retinoic Acid Sensitivity in Pancreatic Cancer
Authors: Gupta Sonal , Pramanik Dipankar , Mukherjee Radha , Campbell Nathaniel R. , Elumalai Sathyanarayanan , de Wilde Roeland F. , Hong Seung-Mo , Goggins Michael G. , De Jesus-Acosta Ana , Laheru Daniel , Maitra Anirban
Published: April 2023

PDF file - 115K
Supplementary Figure 3 from Molecular Determinants of Retinoic Acid Sensitivity in Pancreatic Cancer
Authors: Gupta Sonal , Pramanik Dipankar , Mukherjee Radha , Campbell Nathaniel R. , Elumalai Sathyanarayanan , de Wilde Roeland F. , Hong Seung-Mo , Goggins Michael G. , De Jesus-Acosta Ana , Laheru Daniel , Maitra Anirban
Published: April 2023

PDF file - 117K
Supplementary Figure 2 from Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Authors: Zhang Yi-Xiang , van Oosterwijk Jolieke G. , Sicinska Ewa , Moss Samuel , Remillard Stephen P. , van Wezel Tom , Bühnemann Claudia , Hassan Andrew B. , Demetri George D. , Bovée Judith V.M.G. , Wagner Andrew J.
Published: April 2023

Supplementary Figure 2 - PDF file 183K, S6 phosphorylation in chondrosarcoma clinical tissue microarray samples
Supplementary Table 1 from Association between VEGF Splice Isoforms and Progression-Free Survival in Metastatic Colorectal Cancer Patients Treated with Bevacizumab
Authors: Bates David O. , Catalano Paul J. , Symonds Kirsty E. , Varey Alex H.R. , Ramani Pramila , O'Dwyer Peter J. , Giantonio Bruce J. , Meropol Neal J. , Benson Al Bowen , Harper Steven J.
Published: April 2023

PDF file - 37K, Comparison of study cases and overall patient population
Supplementary Figure 1 from Association between VEGF Splice Isoforms and Progression-Free Survival in Metastatic Colorectal Cancer Patients Treated with Bevacizumab
Authors: Bates David O. , Catalano Paul J. , Symonds Kirsty E. , Varey Alex H.R. , Ramani Pramila , O'Dwyer Peter J. , Giantonio Bruce J. , Meropol Neal J. , Benson Al Bowen , Harper Steven J.
Published: April 2023

PDF file - 260K, Scoring of immunohistochemically stained samples
Supplementary Tables 1-4 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

PDF file - 95K
Supplementary Table 1 from The Cyclin-Dependent Kinase Inhibitor Flavopiridol Potentiates Doxorubicin Efficacy in Advanced Sarcomas: Preclinical Investigations and Results of a Phase I Dose-Escalation Clinical Trial
Authors: Luke Jason J. , D'Adamo David R. , Dickson Mark A. , Keohan Mary Louise , Carvajal Richard D. , Maki Robert G. , de Stanchina Elisa , Musi Elgilda , Singer Samuel , Schwartz Gary K.
Published: April 2023

PDF file - 66K, Cumulative grade 2 or greater hematologic toxicity throughout all cycles.
Supplementary Table S2 from Poor Concordance among Nine Immunohistochemistry Classifiers of Cell-of-Origin for Diffuse Large B-Cell Lymphoma: Implications for Therapeutic Strategies
Authors: Coutinho Rita , Clear Andrew James , Owen Andrew , Wilson Andrew , Matthews Janet , Lee Abigail , Alvarez Rute , da Silva Maria Gomes , Cabeçadas José , Calaminici Maria , Gribben John G.
Published: April 2023

PDF file 51K, Supplementary Table S2 Distribution of R-CHOP treated patients diagnosed in the two institutions according to the nine IHC classifiers
Supplementary Figure 6 from Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase Expression
Authors: Contractor Kaiyumars , Challapalli Amarnath , Barwick Tara , Winkler Mathias , Hellawell Giles , Hazell Steve , Tomasi Giampaolo , Al-Nahhas Adil , Mapelli Paola , Kenny Laura M. , Tadrous Paul , Coombes R. Charles , Aboagye Eric O. , Mangar Stephen
Published: April 2023

PDF file - 155K
Supplementary Figure Legend from Poor Concordance among Nine Immunohistochemistry Classifiers of Cell-of-Origin for Diffuse Large B-Cell Lymphoma: Implications for Therapeutic Strategies
Authors: Coutinho Rita , Clear Andrew James , Owen Andrew , Wilson Andrew , Matthews Janet , Lee Abigail , Alvarez Rute , da Silva Maria Gomes , Cabeçadas José , Calaminici Maria , Gribben John G.
Published: April 2023

PDF file 44K, Legend for Supplementary Figure 1
Supplementary Table 1 from Biomarker and Pharmacologic Evaluation of the γ-Secretase Inhibitor PF-03084014 in Breast Cancer Models
Authors: Zhang Cathy C. , Pavlicek Adam , Zhang Qin , Lira Maruja E. , Painter Cory L. , Yan Zhengming , Zheng Xianxian , Lee Nathan V. , Ozeck Mark , Qiu Ming , Zong Qing , Lappin Patrick B. , Wong Anthony , Rejto Paul A. , Smeal Tod , Christensen James G.
Published: April 2023

XLS file, 53K, Target sequences NanoString assays.
Supplementary Figure 4 from Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
Authors: Kanerva Anna , Nokisalmi Petri , Diaconu Iulia , Koski Anniina , Cerullo Vincenzo , Liikanen Ilkka , Tähtinen Siri , Oksanen Minna , Heiskanen Raita , Pesonen Saila , Joensuu Timo , Alanko Tuomo , Partanen Kaarina , Laasonen Leena , Kairemo Kalevi , Pesonen Sari , Kangasniemi Lotta , Hemminki Akseli
Published: April 2023

PDF file - 95K, A panel of proinflammatory cytokines was analyzed to evaluate the safety of treatment.
Supplementary Table 3 from Functional, Genetic, and Epigenetic Aspects of Base and Nucleotide Excision Repair in Colorectal Carcinomas
Authors: Slyskova Jana , Korenkova Vlasta , Collins Andrew R. , Prochazka Pavel , Vodickova Ludmila , Svec Jiri , Lipska Ludmila , Levy Miroslav , Schneiderova Michaela , Liska Vaclav , Holubec Lubos , Kumar Rajiv , Soucek Pavel , Naccarati Alessio , Vodicka Pavel
Published: April 2023

PDF file, 57K, Table shows list of genes analyzed by MS-HRM with their respective primers sequences and reaction conditions.
Supplementary Table 1 from Functional, Genetic, and Epigenetic Aspects of Base and Nucleotide Excision Repair in Colorectal Carcinomas
Authors: Slyskova Jana , Korenkova Vlasta , Collins Andrew R. , Prochazka Pavel , Vodickova Ludmila , Svec Jiri , Lipska Ludmila , Levy Miroslav , Schneiderova Michaela , Liska Vaclav , Holubec Lubos , Kumar Rajiv , Soucek Pavel , Naccarati Alessio , Vodicka Pavel
Published: April 2023

PDF file, 65K, Table shows list of genes analyzed by qPCR with their respective primers sequences and reaction conditions.
Supplementary Table 2 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 59KB, Expanded normal tissue IHC analysis of B7-H3 on frozen tissues with MGA271 at optimal staining concentration (4 ug/ml) and at 5x the optimal concentration (20 ug/ml). The optimal staining concentration was determined by titration on the CaKi2 and Hs700T positive control cell lines to determine the lowest MGA271 concentration that yielded the greatest specific staining. (c) = cytoplasmic; (m) = membrane; (c,m) = cytoplasmic plus membrane.
Supplementary Figure 4 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 78KB, Measurement of the absolute level of circulating B cells (CD20+; Panel A), T cells (CD3+; Panel B) and NK cells (CD159a+)Panel C) in blood samples collected from cynomolgus monkeys at the indicated days prior to administration (Day -2), or following intravenous administration of PBS vehicle on Day 1 (all animals received PBS vehicle on Day 1) or MGA271 on Day 8 at the indicated dose. The panels on the left for each group represent all animals (N=6) in each dosing group, while the panels on the right represent only the recovery group animals (N=2) in each dosing group.
Supplemental Table 2 from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

List of pGBMs and their respective passage numbers used for the various experimental paradigms in this study.
Supplementary Figure 2 from Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
Authors: Loo Deryk , Alderson Ralph F. , Chen Francine Z. , Huang Ling , Zhang Wenjun , Gorlatov Sergey , Burke Steve , Ciccarone Valentina , Li Hua , Yang Yinhua , Son Tom , Chen Yan , Easton Ann N. , Li Jonathan C. , Rillema Jill R. , Licea Monica , Fieger Claudia , Liang Tony W. , Mather Jennie P. , Koenig Scott , Stewart Stanford J. , Johnson Syd , Bonvini Ezio , Moore Paul A.
Published: April 2023

PDF file, 75KB, Expression level of B7-H3 on ATCC cancer cell lines as determined by FLOW cytometry with anti-B7-H3 mAb BRCA84D. Solid curves represent isotype control staining; open curves represent staining with FI.
Supplemental Figure 1 from Anticancer Effects of Niclosamide in Human Glioblastoma
Authors: Wieland Anja , Trageser Daniel , Gogolok Sabine , Reinartz Roman , Höfer Heike , Keller Mihaela , Leinhaas Anke , Schelle Ramona , Normann Sabine , Klaas Lil , Waha Andreas , Koch Philipp , Fimmers Rolf , Pietsch Torsten , Yachnis Anthony T. , Pincus David W. , Steindler Dennis A. , Brüstle Oliver , Simon Matthias , Glas Martin , Scheffler Björn
Published: April 2023

Niclosamide dose-response curves.
Supplementary Figure 3 from Spleen Cells from Young but Not Old Immunized Mice Eradicate Large Established Cancers
Authors: Schreiber Karin , Arina Ainhoa , Engels Boris , Spiotto Michael T. , Sidney John , Sette Alessandro , Karrison Theodore G. , Weichselbaum Ralph R. , Rowley Donald A. , Schreiber Hans
Published: April 2023

PDF file, 163KB.
Supplementary Table 1 from Proliferation in the Normal FTE Is a Hallmark of the Follicular Phase, Not BRCA Mutation Status
Authors: George Sophia H.L. , Milea Anca , Shaw Patricia A.
Published: April 2023

PDF file, 209K, List of significant GO biological process terms highly represented when comparing FTE-BRCA1 to FTE-nonBRCA transcriptome.
Supplementary Figure 1 from Proliferation in the Normal FTE Is a Hallmark of the Follicular Phase, Not BRCA Mutation Status
Authors: George Sophia H.L. , Milea Anca , Shaw Patricia A.
Published: April 2023

PDF file, 597K, A. Demonstration of immunohistochemical analyses of the Ki67 stain was performed by 2 independent observers (blinded), where 0 < 1%, 1= 1%, 2=2 - 4%, 3=5 - 15% and 4> 4%. B. Distribution of Ki67 scores, by independent observers between FTE-BRCA1/BRCA2 mutation carriers and FTE-nonBRCA.
Supplemental Material Section S5 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 144K, Resampling strategy to identify miRNA markers.
Supplementary Table 3 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

XLSX file - 155K, Excel file of probe sets that were associated with survival in the Uppsala cohort for all histological subtypes, adenocarcinoma and sqaumous cell cancer