bluuebunny/crossref_metadata_2025 huggingface dataset:
Female Genital Tuberculosis in Pakistan – a Retrospective Review of 10-Year Laboratory Data and Analysis of 32 Cases
Authors: Fatima Tazeen , Hasan Rumina , Malik Faisal Riaz , Ahmed Imran , Bartlett Linda Alice , Gravett Michael G. , Shakoor Sadia
Published: April 2023

Background:

Female genital tuberculosis (FGTB) is an underobserved clinical entity owing to diagnostic challenges stemming from difficulty of obtaining diagnostic specimens and paucibacillary nature of the disease. Yet, FGTB is a cause of infertility, pelvic pain, or menstrual irregularities in high-burden countries. To assess laboratory and microbiology diagnostic utilization for FGTB in Pakistan, we have collected data from 2007 to 2016 to inform the need for improved laboratory diagnostics. The objectives of this study were to determine the proportion of FGTB as culture-confirmed extrapulmonary tuberculosis (EPTB) and to describe the characteristics of women with culture-confirmed FGTB in a nationwide laboratory network in Pakistan.

Method:

A retrospective database was established by accessing laboratory archives and analyzed by sex and source to determine extrapulmonary cases among women. Data were checked for quality, and after removing patient identifiers and duplicate samples, frequencies were calculated in MS Excel. Clinical characteristics of patients were derived from a linked hospital database for those patients who were diagnosed and managed at the affiliated university hospital in Karachi, Pakistan.

Results:

Over 10 years, 410,748 mycobacterial cultures were received from multiple geographic sites throughout Pakistan and processed at the study laboratory. The overall mean culture positivity rate was 5.9% ± 3.5%, while the mean culture positivity rate among females was 2.8% ± 0.8%. Among female culture-confirmed tuberculosis cases, the pulmonary-to-EPTB ratio of infection was 5. Over 10 years, a total of 32 FGTB cases were reported on the basis of positive cultures for Mycobacterium tuberculosis; 3 (9.4%) were rifampin resistant.

Conclusions:

FGTB currently constitutes a small but significant proportion of culture-confirmed EPTB. A fewer number of laboratory requisitions suggest the need to increase awareness and testing. The advent of high-sensitivity molecular testing on extrapulmonary specimens has the potential to improve diagnostic accuracy and improved detection of FGTB cases in high-burden regions.
Primary Tubercular Granulomatous Hepatitis Presenting as Fluctuating Jaundice
Authors: Dhali Arkadeep , Dhali Gopal Krishna , Ghosh Ranajoy , Sarkar Avik
Published: April 2023

Granulomatous hepatitis is an uncommon presentation of tuberculosis (TB). It is even more peculiar to have TB confined to the liver alone with no pulmonary or a disseminated form. In either form, there is the usual presentation of nonprogressive cholestatic jaundice, but no documented case with fluctuating jaundice in the literature was found. In order to highlight this rare presentation aiding the right diagnosis, we present one such case of a 46-year-old woman with no known comorbidities, who complained of fluctuating and painless type of jaundice, associated with fatiguability, pruritus, and weight loss. Preliminary blood investigations showed anemia and cholestatic pattern of jaundice. Ultrasonography and computed tomography imaging showed hepatomegaly with heterogeneous texture. Magnetic resonance cholangiopancreatography further revealed features of cholecystitis with hepatic ducts near proximal common bile duct showing postinflammatory change. The periampullary region was normal. Sputum acid-fast staining and cartridge-based nucleic acid amplification test were negative. Eventually, liver biopsy was done which showed caseating granulomas with Langhans giant cells. The tissue was abundant in acid-fast bacilli. The patient was started on a 9-month course of first-line Antitubercular treatment (ATT) and responded well. Fluctuating jaundice is a rare and undocumented presentation of primary hepatic TB and can cause diagnostic dilemmas.
War-Related Mental Health Issues and Need for Yoga Intervention Studies
Authors: Anand Akshay , Ghani Abdul , Sharma Kanupriya , Kaur Gurkeerat , Khosla Radhika , Devi Chandra , Podder Vivek , Sivapuram Madhava S. , Maity Kalyan , Kaur Harmandeep
Published: April 2023

Conflicts and humanitarian crises lead to serious mental health disorders, including depression, anxiety, stress, and cognitive decline. Exposure to these circumstances in early life can lead to the development of disorders such as mild cognitive impairment, dementia, and Alzheimer's disease (AD), for which no treatments are available. In this review, various research papers have been compiled to develop an understanding about mental health of population affected due to wars and conflicts and how stress and depression can accelerate the development of dementia and AD. Due to failure of drugs in the treatment of dementia and AD, yoga and mindfulness-based approach has been proposed for future investigations. Although studies have shown that yoga and mindfulness can be helpful in the management of stress, anxiety, depression, and posttraumatic stress disorder in the war-afflicted areas, limited mechanistic studies in yoga and mindfulness remain the chief cause precluding its clinical application in such warzones. The molecular studies in the field of yoga can be undertaken by targeting these warzones. This review provides a scientific evaluation of mind–body techniques as a justification for mental health rehabilitation in the war-afflicted zones in face of failed clinical trials for various drugs. This may help reduce the risk of developing dementia and AD in this susceptible population.
Mind-Body Wellness
Authors: Pastan Christina DiBona
Published: April 2023

We strive in dental education to train our students to leave dental school with a skill set that enables them to be competent in diagnosis, treatment planning, and in their technical skills to treat their patients. We do not however train our students in practices to maintain their physical and mental well-being, cope with the demands of the dental school curriculum, and provide a toolbox of skills to manage the stresses of dentistry that will be with them for as long as they practice. The COVID-19 pandemic has added a new layer of stress on dental students and although the topic of wellness has been addressed in various ways in dental school environments, integrating a wellness component that supports our student's vulnerabilities while also teaching skills to build resilience to adversity is a needed and missing component in the dental curriculum. Elective stress management wellness courses have been implemented in dental schools and although this is a promising start, the demands of the dental school curriculum make it a difficult environment to become relaxed, grounded, and focused. Based on 6 years of experience in creating and implementing an integrated wellness program at an academic dental institution, this article aims to outline the benefits and applications for teaching mind-body practices in the dental school curriculum as preventative approaches to maintaining overall student wellness, for developing effective strategies to manage academic and clinical challenges and how it sets the foundation for the health, well-being, and professional mindset of future dentists.
Prevalence of panton–Valentine leukocidin and toxic shock syndrome toxin-1 genes in methicillin-resistant Staphylococcus aureus isolated from nose of restaurant workers in Kirkuk city
Authors: Mahdi Najdat Bahjat
Published: April 2023

Staphylococcus aureus resides naturally in the nasal cavity of healthy individuals, including those working in restaurants, so they may be a source for spreading this bacterium to restaurant customers directly or indirectly through cooked meals. This bacterium has several virulence factors enabling it to cause many diseases in different parts of the body. It has also the capability to resist conventional antibiotics including methicillin. To investigate methicillin-resistant S. aureus (MRSA), 170 nasal swabs were collected from food preparation workers in 30 restaurants (5–6 workers in each restaurant) in Kirkuk city. After collection, the samples were directly transferred to the laboratory and cultured on selective media like mannitol salt agar (MSA). Microbiological examination including morphological, biochemical, and confirmatory tests showed that 24/170 of collected samples were positive for S. aureus with a rate of 14.12%. Among 24 isolates, 20 (83.3%) belonged to MRSA. All isolates were resistant to oxacillin and penicillin (100%), whereas sensitive to other antibiotics (gentamicin, chloramphenicol, and rifampicin). Polymerase chain reaction exhibited that 13 (65%) of MRSA isolates have toxic shock syndrome toxin-1 gene and only 4 (20%) have Panton–Valentine leukocidin gene.
Bioactive phytoconstituents of ethanolic extract from Chromolaena odorata leaves interact with vascular endothelial growth factor and cyclooxygenase-2
Authors: Teuku Husni TR , Darmawi Darmawi , Azwar Azwar , Jamil Kurnia Fitri
Published: April 2023

Chromolaena
odorata is an invasive plant with a broad spectrum of medicinal properties, including wound healing. This study aimed to evaluate the interaction of the already identified bioactive phytoconstituents from ethanolic extracts of C.
odorata leaves with two angiogenesis-related proteins – vascular endothelial growth factor (VEGF) and cyclooxygenase-2 (COX-2) in silico. A molecular docking protocol was performed on AutoDock Vina employing the molecular structure of VEGF (3HNG) and COX-2 (3LN1) downloaded from the Protein Data Bank. The results reveal that most of the phytoconstituents possess strong binding affinity, where β-tocopherol and squalene have the highest values. In conclusion, it is highly possible that the phytoconstituents of C.
odorata from the ethanolic leaf extract perform an interaction with VEGF and COX-2 and affect their activities.
Computational approach in searching for dual action multitarget inhibitors for osteosarcoma
Authors: Gani Maria Apriliani , Nurhan Ahmad Dzulikri , Hadinar Putri Bulan Rhea Kaulika , Suyatno Andhi , Khan Shakil Ahmed , Ardianto Chrismawan , Rantam Fedik Abdul , Khotib Junaidi
Published: April 2023

Osteosarcoma is a common primary malignant bone tumor that typically manifests in the second decade of life. This study aimed to identify osteogenic compounds that potentially serve as multitarget inhibitors for osteosarcoma. The study was a molecular docking study of nine Food and Drug Administration-approved compounds with osteogenic properties to the key membrane proteins of osteosarcoma. The ligands used were raloxifene, simvastatin, dexamethasone, risedronate, ibandronate, zoledronic acid, ascorbic acid, alendronate, and β-glycerophosphate, whereas the target proteins used were RET, fibroblast growth factor receptor 1, KIT, PDGFRA, VEGFR1, and VEGFR2. Chem3D version 15.0.0.106 was used for ligand preparation, and AutoDockTools version 1.5.6 was used for protein preparation, whereas molecular docking was conducted using AutoDock Vina. Raloxifene, simvastatin, and dexamethasone had the lowest binding activity to the target proteins. The binding affinity of raloxifene was from −8.4 to −10.0 kcal mol−1, that of simvastatin was −8.3 to −9.2 kcal mol−1, whereas dexamethasone ranged from −6.9 to −9.1 kcal mol−1. Most types of interactions were hydrophobically followed by hydrogen bonding. The current study suggests that raloxifene, simvastatin, and dexamethasone have the potential to act as multitarget inhibitors for osteosarcoma with the ability to induce bone remodeling.
Investigations of chemical compositions and antioxidative potential of essential oils isolated from the leaves of two Garcinia species
Authors: Kokilananthan Shanthirasekaram , Bulugahapitiya Vajira P. , Manawadu Harshi , Gangabadage Chinthaka Sanath
Published: April 2023

Garcinia quaesita and Garcinia zeylanica are Sri Lankan endemic plants with significant therapeutic potential and numerous health-care applications. Despite this, there are no adequate literatures reported on the chemical compositions (CCs) and antioxidative potential (AP) of leaves' essential oils (EOs). The purpose of this study was to extract EOs from the leaves and investigate the CCs and AP of the extracted EOs. The hydro-distillation technique was used to extract the EOs, and the CCs of the EOs were identified through gas chromatography–mass spectrometry analysis. Only those compounds that had a matching value of more than 90% were taken into consideration, and the AP of the extracted EOs was determined using the ferric-reducing antioxidant power (FRAP) assay. Hydro-distillation process yielded EOs in the same quantity, 0.12% (v/w) on a fresh weight basis for two varieties. About 33 CCs that were found in the extracted EOs were mainly sesquiterpenes. The most prevalent substances in the EOs were copaene (19.39%), caryophyllene (12.94%), alloaromadendrene (12.12%), α-humulene (11.24%), and α-cubebene (9.38%). It is interesting to note that copaene and alloaromadendrene were only found in G. quaesita, whereas α-cubebene was only found in G. zeylanica. Caryophyllene and α-humulene were identified in both EOs at different concentrations. The EO from G. quaesita showed high AP, presenting FRAP values 274.74 ± 1.32 μL Trolox Eq/L. This study is recognized as being the first to examine the CCs and AP of EOs, and the results may inspire the creation of new uses and high-value leaf products.
Laparoscopic transperitoneal adrenalectomy for adrenal tumours of 6 cm or greater: A single-centre experience
Authors: Öz Bahadır , Cücük Ömer , Gök Mustafa , Akcan Alper , Sözüer Erdoğan
Published: April 2023

Background:

The present study aimed to evaluate the safety and efficacy of transperitoneal laparoscopic adrenalectomy (LA) for large adrenal tumours by comparing the outcomes of tumours larger than 6 cm with those smaller than 6 cm and also to identify the risk factors associated with prolonged operative time in transperitoneal LA.

Patients and Methods:

One hundred and sixty-three patients underwent LA at our clinic from January 2014 to December 2020. Bilateral LA was performed in 20 of these 163 patients. A total of 143 patients were included in this study. Data were analysed retrospectively from the patients’ medical records collected.

Results:

Large tumour (LT) group consists of 33 patients and the small tumour (ST) group consists of 110 patients. There was no statistically significant difference between the groups regarding conversion to open surgery and complications. A multiple regression analysis was conducted to identify the independent predictors of prolonged operation time. The tumour size ≥8 cm (odds ratio [OR], 19.132; 95% confidence interval [CI], 3.881–94.303; P < 0.001) and diagnosis of pheochromocytoma (OR, 2.762; 95% CI, (1.123–6.789, P = 0.026) were the significant predictors of prolonged operation time.

Conclusion:

Our study shows that LA can be considered the treatment of choice for small and large adrenal tumours. The tumour size ≥8 cm and diagnosis of pheochromocytoma are the independent risk factors for the prolonged operative time in transperitoneal LA.
Awake uniportal video-assisted thoracoscopic surgery for the management of pericardial effusion
Authors: Çardak Murat Ersin , Külahçioglu Seyhmus , Erdem Esin
Published: April 2023

Introduction:

Pericardial drainage can be performed either with pericardiocentesis or pericardial “window” in cases with hemodynamic compromise for therapeutic and diagnostic purposes. Awake single-port video-assisted thoracoscopic surgery (VATS) is an alternative to pericardial window (PW) that has been described only in case reports in the literature. We aimed to analyse a series of patients with chronic, recurrent and/or large pericardial effusions who underwent single-port VATS-PW opening without intubation.

Patients and Methods:

The PW was opened using awake single-port VATS in 20 of 23 patients referred to our clinic with recurrent, chronic and/or large pericardial effusion between December 2021 and July 2022. Demographic data, imaging modalities, treatment processes and pathological samples were analysed retrospectively.

Results:

The median age of 20 patients was 68 years (52–81). The mean body mass index was 29.1 ± 6.0 kg/m2 and mean pericardial fluid measurements with pre-operative transthoracic echocardiography (TTE) was 2,8 ± 0,9 cm. The mean operation time was 44 ± 13.0 min and mean peri-operative drainage was 700 ± 307 cc. On the 1st post-operative day, control TTE revealed ≤0.5 cm effusion in 18 (90%) patients and ≥0.5 cm in 2 (10%) patients. The median day of discharge or referral to the clinic where they are followed up was 1 (1–2).

Conclusions:

Awake single-port VATS could be used safely in all patient groups with pericardial effusion or tamponade as a diagnostic and therapeutic option. This technique has advantages, especially in patients with high surgical risk.
Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology of Pancreatic Adenocarcinomas Revisited. A Detailed Cytological Analysis
Authors: Mallik Mrinmay Kumar , Kapila Kusum , Mohanty Asit Kumar , Inamdar Shafi Ahmed , AlAli Ali , Al Naseer Abdullah
Published: April 2023

Background:

Early detection of pancreatic adenocarcinomas is essential for improving survival. In this regard, endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) has established itself as the method of choice for its ability to target lesions smaller than those which could be targeted by the traditional imaging methods like transabdominal ultrasound. Identifying these tumors correctly on FNA may be challenging because pancreatic adenocarcinomas may show a wide range of morphological features and the presence of contaminants from the gastrointestinal tract may show up as potential pitfalls. This study presents detailed cytomorphological analyses of 59 cases reported as pancreatic adenocarcinomas on smears and cell blocks. The clinical and histopathology follow-up data wherever available have also been presented.

Materials and Methods:

EUS-FNAC smears and cell blocks from cases reported as pancreatic adenocarcinomas were retrospectively evaluated with individual assessments of a range of features related to cellularity, cellular arrangement, cytoplasmic qualities, and nuclear features. Aspirates from peripancreatic lymph nodes, histopathology sections, and clinical records were reviewed wherever available.

Results:

Nonneoplastic cells like pancreatic ductal cells and acinar cells, duodenal, and gastric epithelia were detected along with neoplastic cells showing a wide range of variations in different cytomorphological characters. Often, a mixture of features was noted in the same case. Cell block preparations served as useful adjuncts since they made it possible to render unequivocal diagnoses of malignancies in cases where smears were hypocellular.

Conclusion:

The study creates a useful knowledge base of cytomorphological features of pancreatic adenocarcinomas.
Evaluation of Human Papillomavirus Genotype Distribution in Cervical Samples
Authors: Bakir Ayfer , Alacam Sema , Karabulut Nuran , Beka Hayati , Ozluk Yasemin , Yilmazbayhan Dilek , Agacfidan Ali
Published: April 2023

Background:

The most common sexually transmitted infection in the world is human papillomavirus (HPV). HPV types 16 and 18 are responsible for 60–80% of cervical cancers and precancerous cervical lesions worldwide.

Aim:

In this study, it was aimed to evaluate the correlation of HPV genotype distribution with cervical cytology results in cervical smear samples and to contribute to HPV epidemiology.

Materials and Methods:

This study included 72 female patients. For detection of the HPV genotypes, a multiplex real-time polymerase chain reaction (PCR) method that could detect more than 25 different HPV types was used. The cervical cytology and histopathology results of the patients were also evaluated simultaneously.

Results:

The frequency of high-risk HPV was 35% (25/72). The most common types were HPV51 (10%), HPV16 (8%), and HPV66 (8%), respectively. The most common type HPV51 and multiple HPV types were seen in 21–34 age groups. HPV DNA was detected in 21 of 43 samples that had cervical smear diagnosis grouping. Twelve samples (26%) had normal cytology. Low grade squamous intraepithelial lesions were the most common cytological diagnosis in HPV DNA positive samples. The most common HPV types in the patients diagnosed low grade squamous intraepithelial lesions and high grade squamous intraepithelial lesions were HPV16 and HPV52.

Conclusions:

In this study, the frequency of high-risk HPV genotypes was 35% as similar to reports of the other studies conducted in our country. The most common types were HPV51, HPV16, and HPV66, respectively. The follow-up of patients with HPV51 infection in our area could help to improve the natural course of the disease and effective prevention programs.
Edge states for second order elliptic operators in a channel
Authors: Gontier David
Published: April 2023

We present a general framework to study edge states for second order elliptic operators in a half channel.We associate an integer valued index to some bulk materials, and we prove that, for any junction between two such materials, localized states must appear at the boundary whenever the indices differ.
Activity recognition of stroke‐affected people using wearable sensor
Authors: David Anusha , Ramadoss Rajavel , Ramachandran Amutha , Sivapatham Shoba
Published: April 2023

Stroke is one of the leading causes of long‐term disability worldwide, placing huge burdens on individuals and society. Further, automatic human activity recognition is a challenging task that is vital to the future of healthcare and physical therapy. Using a baseline long short‐term memory recurrent neural network, this study provides a novel dataset of stretching, upward stretching, flinging motions, hand‐to‐mouth movements, swiping gestures, and pouring motions for improved model training and testing of stroke‐affected patients. A MATLAB application is used to output textual and audible prediction results. A wearable sensor with a triaxial accelerometer is used to collect preprocessed real‐time data. The model is trained with features extracted from the actual patient to recognize new actions, and the recognition accuracy provided by multiple datasets is compared based on the same baseline model. When training and testing using the new dataset, the baseline model shows recognition accuracy that is 11% higher than the Activity Daily Living dataset, 22% higher than the Activity Recognition Single Chest‐Mounted Accelerometer dataset, and 10% higher than another real‐world dataset.
Effective purification of high concentration chromium-containing wastewater and preparation of chromium ferrite
Authors: Chen Dan , Sheng Wenyu , Wang Daoyuan , Meng Yuan , Yang Haozhong , Liu Yu , Qian Guangren
Published: April 2023

The formation of valuable ferrite in one step by adding ferrous sulfate to chromium-containing wastewater without adjusting to acidic conditions was studied under simple mechanical equipment. The process can not only solve the problem of heavy metals removal from wastewater, but also achieve the purpose of chromium resource recovery. Increasing temperature and pH can further promote the formation of chromium ferrite while prolonging the reaction time has no significant effect on the product’s performance. The response surface method (RSM) was utilized to optimize the process of ferrite formation: the Fe2+/Cr6+ mole ratio of 7, pH value of 10.5, and temperature of 100℃, on which formed ferrite has a high saturation magnetization of 41.28 emu/g with Cr(VI) removal ratio around 100%. TCLP (Toxicity Characteristic Leaching Procedure) tests showed that the chromium concentrations leached from the solid were below the limit of 5 mg/L by USEPA. The molecular formula of chromium ferrite can be expressed as Fe3-xCrxO4 (where x is about 0.45), which has the potential to be recycled as a favorable material. The ferrite process has a low activation energy of 20.8 kJ/mol, which is an economical and environmentally friendly method for synthesizing ferrite from wastewater.
Life in the Debt Trap
Authors: Mahony Sorcha , Pople Larissa
Published: April 2023

The first hand stories in this book, collected through The Children's Society's campaign 'The Debt Trap', offer a unique understanding of life for families and children fighting a daily battle against poverty and debt.
Countering Extremism in British Schools?
Authors: Holmwood John , O'Toole Therese
Published: April 2023

In 2014 the 'Trojan Horse' affair, an alleged plot to 'Islamify' several state schools in Birmingham, caused a previously highly successful school to be vilified. Holmwood and O'Toole challenge the accepted narrative and show how it was used to justify an intrusive counter extremism agenda.
A Watershed Moment for Social Policy and Human Rights?
Authors: Clair Amy , Fledderjohann Jasmine , Knowles Bran
Published: April 2023

This book demonstrates that an alternative approach to social policy, based on human rights and social justice, is necessary to tackle the existing systemic inequalities brought to the foreground by COVID-19.
Erich Fromm and Global Public Sociology
Authors: McLaughlin Neil
Published: April 2023

As the rise of global right-wing populism and Trumpism creates new interest in psycho-social writing and popular sociology, this timely book tells the story of the rise, fall and contemporary revival of the theories of Erich Fromm, a 1930s influential and creative public intellectual.
Is Europe Good for You?
Authors: Dellmuth Lisa
Published: April 2023

This important book investigates how the European Union (EU) can use its regional funding programmes in ways that increase citizen well-being. It argues the case for enhancing the inclusivity of EU growth, which yields the promise of a more legitimate and stronger union.
Ports, Crime and Security
Authors: Sergi Anna , Reid Alexandria , Storti Luca , Easton Marleen
Published: April 2023

The COVID-19 pandemic, Brexit and the US-China trade dispute have heightened interest in the geopolitics and security of modern ports. Applying a multidisciplinary lens to the political economy of port security, this book presents a unique outlook on the social, economic and political factors that shape organised crime and governance.
Development of Pesantren Curriculum in Improving the Quality of Education (Case Study at Al-Ittihad Islamic Boarding School, Poncol, Al-Huda Islamic Boarding School, Petak, Semarang Regency)
Authors: Martono Martono
Published: April 2023

Microsoft Office Translator

This study aims to analyze the process of developing the yellow book curriculum of pesantren in improving the quality of education at Al-Ittihad Poncol Islamic Boarding School, Al-Huda Islamic Boarding School Petak Semarang Regency. To analyze the implications of developing the yellow book curriculum in improving the quality of education in the Al-Ittihad Poncol Islamic Boarding School in Semarang Regency and the Al-Huda Islamic Boarding School in Semarang Regency, to analyze the reasons why the yellow book curriculum needs to be applied in the Islamic boarding school environment in Indonesia. This research uses a qualitative approach with natural characteristics (Natural Setting) as a source of direct, descriptive data, process is more important than results. Primary data of caregivers, heads of Islamic boarding schools, chairmen and representatives of the curriculum, ustadz, and Santri sons / daughters of Al-Ittihad Poncol Islamic boarding school and Al-Huda Petak Islamic boarding school. Data collection techniques with in-depth interviews, observation and documentation. Data analysis uses descriptive analysis methods, content analysis and critical analysis. The Discussion Method uses, inductive method, deductive method and comparative method. The results of this study are a) The history of al-Ittihad Islamic Boarding School and al-Huda Islamic Boarding School developed from Sufism Islamic boarding schools, studying the Qur'an and studying the yellow book using the classical system, b) The development process of Islamic boarding schools Pesantren al-Ittihad and Pesantren al-Huda through planning, organizing, implementing and controlling, in accordance with existing theories, c) Implications of Pesantren al-Ittihad and Pesantren al-Huda in their development on quality Education has two aspects, namely: Characteristics of quality Pesantren Education and curriculum development, d) The Yellow Book curriculum must still be applied in Islamic boarding schools in Indonesia: a) The yellow book has been tested for hundreds of years. b) The Yellow Book is still authentic (preserved authenticity), c) Ease of access, d) memorization, accuracy and a lot of practice.
CUTTING FREQUENCY IN CAYMAN GRASS (Urochloa HYBRID) ON THE CALORIFIC POWER OF THE MEXICAN WET TROPIC
Authors: Ventura-Ríos Joel , Rojas-García Adelaido Rafael , Barrera-Martínez Iliana , García-Salas Alejandro , Maldonado-Peralta María de los Ángeles
Published: April 2023

The objective of this study was to evaluate the effect of cutting frequency in Cayman grass (Urochloa HYBRID) on biomass yield, moisture, ash, ethereal extract, neutral detergent fiber (FDN), acid detergent fiber (FDA), acid detergent lignin (LDA), crude protein (PC), calorific value, and theoretical bioethanol yield. Four cutting frequencies were established as treatments: 30, 60, 90, and 120 d, arranged in a completely randomized block design with three replications. Data were analyzed with GLM (SAS), and means were compared with the Tukey test (p ≤ 0.05). The highest biomass production (11.9 Mg ha-1 year-1), calorific value (15.1 MJ kg-1), and LDA (5.7 %) were obtained at the 120 d cutting frequency. The concentration of FDN (61.8 %), FDA (43.6 %), cellulose (38.1 %), and theoretical bioethanol production (218.4 L Mg-1 MS) were statistically different at the cutting frequency of 90 d. The values of hemicellulose (18. 7 %) and ethereal extract (1.8 %) were statistically different at the 60 d-cutting frequency; while PC (9.7 %) and ash (11.8 %) showed significant differences at the 30-d cutting frequency. Based on the biomass yield and calorific value of Cayman grass, it can be considered as a potential plant material for cellulosic ethanol production.
Two-stage surgical management of horseshoe lung associated with congenital pulmonary airway malformation in a neonate: A case report
Authors: Polit-Guerrero Veronica , Andrade-Montesdeoca Jimmy , Fabre-Parrales Ernesto , Salinas-Salinas Vicente , Acosta-Farina Daniel
Published: April 2023

Background: Horseshoe lung is a rare congenital malformation, and even rarer is its association with congenital pulmonary airway malformations.
Case Presentation: We report a case of horseshoe lung associated with congenital pulmonary airway malformation (Stocker type 2) who underwent surgical management in two stages. The patient had a right posterolateral thoracotomy with lower right lobectomy at 14 days of life, followed by a left posterolateral thoracotomy with lower left lobectomy at 7 months of age. He is doing fine after both surgeries and follow-up visits are ongoing.
Conclusion: The treatment of horseshoe lung should be individualized, surgical management is an effective option and the two-stage approach in neonates would reduce the risk of the simultaneous bilateral procedure.
A Case of Hutch Diverticulum Leading To Non-Functioning Kidney Due To Vesico-Ureteric Reflux
Authors:   Grant Medical College and J J Group of Hospitals, Mumbai, India, Vijayanand Potdar Ojas , Karamnabi Siddiqui Mohammed Ayub ,   Grant Medical College and J J Group of Hospitals, Mumbai, India, Vaidya Kaustubh ,   Grant Medical College and J J Group of Hospitals, Mumbai, India
Published: April 2023

Bladder diverticulum is caused by herniation of the urothelium through the muscular layer of the bladder wall, being formed by mucosa, lamina propria, few muscular fibres and adventitia. Bladder diverticula are classified as congenital or acquired. Congenital ones usually appear in young ages with a maximum incidence before 10 years and are usually unique, almost exclusively in males, located posteromedially to the ureteral ostium and resulting from the weakness of the bladder wall in this portion. Acquired ones generally are due to high intra-vesical pressure caused by infra-vesical obstruction or detrusor-sphincter dyssynergia. More rarely are due to wall debility after bladder surgery. Often develop in males after sixth decade, in about 12% of patients with infra-vesical obstruction. Usually multiple and associated with important trabeculation of the bladder wall. If the ureteral ostium is included in the bladder diverticulum, it is called Hutch diverticulum, which is a rare entity, typically in young ages, with few cases identified in the adult. We hereby present a case of a patient with acquired hutch diverticulum leading to non-functioning kidney due to vesico-ureteric reflux.
Public Debt and Economic Growth: Empirical Evidence from Nigeria
Authors: Tabansi Okeke Callistus , Ann Anisiobi Chinwe , Monica Madueke Chinwe
Published: April 2023

This study examined the impact of public debt on economic growth in Nigeria using annual secondary data from 1981 to 2021 and the Auto-Regressive Distributed Lag technique. The variables used in the study were real gross domestic product (RGDP), which is the proxy for economic growth, gross fixed capital formation (GFCF), external debt (EXDT), exchange rate (EXCR), domestic debt (DODT) and debt service repayment (DSRT). The results of the findings show that the past value of RGDP, GFCF, EXDT and DSRT have positive impact on economic growth in Nigeria. Also, EXCR and DODT have negative impact on economic growth in Nigeria. Judging from the p values, the lagged value of RGDP, GFCF, EXDT and DSRT are statistically significant as their p values are lower than critical values at 5 percent level of significance, while EXCR and DODT have no significant impact on economic growth in Nigeria. Based on the findings, the study recommends that government should formulate and effectively implement policy that would boost domestic revenue generation by broadening the revenue base, improving capacity to tax and curtailing ineffective government spending. Also, borrowed funds should be utilized for the diversification of the productive base of the economy.
Medical education, workforce inequalities, and hierarchical regionalism: the University of Lancaster and the unrealised medical school, 1964-68
Authors: Lambert Michael
Published: April 2023

Part of the justification for the Lancashire and South Cumbria New Hospitals Programme (NHP) is that a modern estateis necessary to attract high quality medical students as an international centre of excellence. Workforce proposals produced by Healthier Lancashire and South Cumbria (LSC) align this with plans for improved recruitment and retention of doctors. These also relate to efforts at reducing reliance on locums and improving patient access to modern specialist services. This interrelationship between the demands of medical education, workforce inequalities, and the organisation of services has a long history which precedes the current NHP proposals. Indeed, it has been a structural feature of the region’s National Health Service (NHS) since 1948. Using the attempt by the newly founded University of Lancaster to obtain a medical school from 1964 to 1968, this paper demonstrates the compounding relationship between medical education, workforce inequalities and hierarchical regionalism as a process of ‘sedimented governance’ which shapes the limits of future horizons for current health services leaders and the NHP.
Machine Learning in Period, Fertility and Ovulation Tracking Application
Authors: Tanmay Thakur  , Saurabh Kadam  , Nikita Patil  , Chinmayee Achrekar
Published: April 2023

Machine learning has the potential to improve the accuracy of period tracking applications by analyzing patterns in menstrual cycle data. The ability to predict the timing of menstrual cycles is important for women's health, and can be used to provide personalized reminders and notifications, as well as to better understand and manage menstrual cycles. One of the main challenges in developing a Machine Learning algorithm for period tracking is the variability of menstrual cycles, which can be affected by a variety of factors such as stress, changes in weight, and certain medical conditions. One approach is to use time series forecasting algorithms, such as ARIMA and STL, which are designed to predict future values based on past data. These algorithms can be trained on historical menstrual cycle data to predict the timing of future cycles. Another approach is to use neural networks, which can model complex patterns in data and can be used to predict the next period date by analyzing patterns in menstrual cycle data, such as cycle length and symptoms. Random Forest and Gradient Boosting are ensemble methods used for classification and regression tasks, which can be used to predict the next period date by analyzing patterns in menstrual cycle data, such as cycle length and symptoms. Support Vector Machines (SVMs) are another Machine Learning algorithm that can be used for prediction, specifically in classification problems. In addition, the accuracy of predictions can be improved by including other relevant data such as information about stress levels, weight changes, and symptoms. Furthermore, by analyzing data from multiple users, machine learning can identify trends and patterns that may be useful in understanding and managing menstrual cycles more effectively. Overall, machine learning has the potential to greatly improve the accuracy and usefulness of period tracking applications, providing women with better tools for understanding and managing their menstrual cycles..
Deep Learning based Automated Billing Cart
Authors: Apurva Sutar  , K. J. Karande  , A. D. Harale
Published: April 2023

Nowadays, shopping malls have become an integralpart of life and people in cities often go shopping malls in order to purchase their daily requirements. In such a place, the environment must be made hassle-free. Our system is mainly designed for edible objects like fruits and vegetables. For edible products like vegetables and fruits, bar-codes and RFID tags cannot be used as they have to be stuck on each of the items and the weight of each item has to be individually measured. The proposed system consists of a camera which detects the commodity using Deep Learning techniques and a load cell which measures the weight of the commodity attached to the shopping cart. This system will generate the bill when the customer scans the item in front of the camera which is fixed on to the Cart. There are many methods for implementation of object detection. Methods like R-CNN use region proposal to generate bounding box and then run a classifier throughout the bounding box. Then the duplications are eliminated using post-processing technique. R-CNN is a slow method for object detection. For this reason, we use YOLO model
A Review on Food Additives, their Health Effects and Natural Alternatives
Authors: Nutan V. Sadgir
Published: April 2023

Food additives are substances added to food during processing to enhance flavor, color, texture, and shelf life. While some food additives are considered safe, others have raised concerns about their potential health effects.it's important to read food labels and be aware of the additives in your food. Choosing whole foods and natural alternatives can help reduce your exposure to potentially harmful additives and promote a healthier diet.There are natural alternatives to many food additives
Strengths-Based Practice to Enhance Mental Health for Autistic People: A Scoping Review
Authors: Murthi Kavitha , Chen Yu-Lun , Shore Stephen , Patten Kristie
Published: April 2023

Importance: Existing autism assessments, interventions, and research focus primarily on deficits rather than strengths, which affects autistic people’s well-being and their physical and mental health.

Objective: To develop an operational definition for strengths-based practice, develop a taxonomy to classify studies that characterize and provide strengths-based assessments and interventions, and present the impact on the mental health and well-being of autistic people of using strengths and interests in practice.

Data Sources: Literature was searched from 2000 to 2021 in the CINAHL, PsycINFO, EBSCOhost, MEDLINE, Web of Science, JSTOR, and ERIC databases.

Study Selection and Data Collection: A five-stage scoping review framework was merged with Joanna Briggs Institute enhancements to scrutinize peer-reviewed studies written in English that characterized and provided strengths-based assessments and interventions.

Findings: We sorted the 38 studies into four categories: strengths-based interventions, descriptive studies, exploratory studies, and commentaries. We found three fundamental themes: mental health outcomes, increased knowledge in interest areas, and supportive environments. Strengths-based interventions were related to positive social engagement, learning, self-advocacy, and anxiety reduction. Descriptive studies used strength assessments and examined stakeholder perceptions of strengths. Exploratory studies explored ways to incorporate strengths in practice. Finally, commentaries discussed the need to presume autistic competence and involve autistic people in research and practice.

Conclusions and Relevance: Despite the small body of literature, these findings have implications for pushing the boundaries of support to center the needs of autistic people and form genuine client collaborations.

What This Article Adds: This article adds to the understanding of using the strengths and interests of autistic people by incorporating their voices into occupational therapy research and practice in meaningful and purposeful ways.

Positionality Statement: This article uses the identity-first language autistic people. This nonableist language describes their strengths and abilities and is a conscious decision. This language is favored by autistic communities and self-advocates and has been adopted by health care professionals and researchers (Bottema-Beutel et al., 2021; Kenny et al., 2016).
Research on the Application of Online and Offline Blended Teaching in the School’s New Media Marketing
Authors:   The Northeast Asian Business and Economic Association (NABEA), Geng Xize , Kong Lingming
Published: April 2023

Purpose - This paper tries to introduce the online-offline hybrid teaching model into the classroom teaching of new media marketing, hoping to stimulate students’ desire to listen to the class through the novel teaching model and improve students’ learning intention and interest. Changing the teaching methods enriches the students’ learning activities in class and after class and improves the teaching effect.
Design/Methodology/Approach - Research the school, objective evaluation, select two classes (control class, experimental class) for teaching design. The data of the experimental and control classes were collected, and the teaching effects were compared from the aspects of the final grade, the ordinary performance, the questionnaire survey and so on, the test scores before and after the analysis, and before and after the analysis of satisfaction.
Findings - Compared with traditional teaching, online-offline hybrid teaching can significantly improve students’ academic performance and satisfaction.
Research Implications - Through the research on the application of online-offline hybrid teaching model in marketing courses, it is beneficial to promote the application of online-offline hybrid teaching in colleges and universities, it is beneficial to optimize the application scheme design of online-offline hybrid teaching. It provides some reference for the practice of online-offline hybrid teaching mode in other disciplines.
Evaluation of Accounting Learning Models: Implementation of Context, Input, Process, and Product (CIPP) Evaluation on Problem-Based Learning Models
Authors: Basuki Basuki , Anriani Nurul
Published: April 2023

Accounting is one of the fields of science that needs more to learn from the theoretical side alone, but it will be easier to understand with real bookkeeping practice. Developing accounting teaching materials is one of the efforts to improve student competence. The learning model with problem base learning is used by lecturers of accounting courses at the University of Muhammadiyah Tangerang. This study aims to evaluate how accounting learning with the PBL model. This type of research is evaluation research that uses a qualitative descriptive methodology and a CIPP assessment model. The results showed that learning Accounting courses using PBL by updating teaching materials, making teaching materials easily accessible to students. The downside of problem-based learning (PBL) is that not all accounting materials can be applied to this model. PBL teaching can increase student engagement in classroom exercises
Near-real-time detection of unexpected atmospheric events using principal component analysis on the Infrared Atmospheric Sounding Interferometer (IASI) radiances
Authors: Vu Van Adrien , Boynard Anne , Prunet Pascal , Jolivet Dominique , Lezeaux Olivier , Henry Patrice , Camy-Peyret Claude , Clarisse Lieven , Franco Bruno , Coheur Pierre-François , Clerbaux Cathy
Published: April 2023

Abstract. The three Infrared Atmospheric Sounding Interferometer (IASI) instruments on board the Metop family of satellites have been sounding the atmospheric composition since 2006. More than 30 atmospheric gases can be measured from the IASI radiance spectra, allowing the improvement of weather forecasting and the monitoring of atmospheric chemistry and climate variables. The early detection of extreme events such as fires, pollution episodes,
volcanic eruptions, or industrial releases is key to take safety measures to protect the inhabitants and the environment in the impacted areas. With its near-real-time observations and good horizontal coverage, IASI can contribute to the series of monitoring systems for the systematic and continuous detection of exceptional atmospheric events in order to support operational decisions. In this paper, we describe a new approach to the near-real-time detection
and characterization of unexpected events, which relies on the principal
component analysis (PCA) of IASI radiance spectra. By analyzing both the
IASI raw and compressed spectra, we applied a PCA-granule-based method on
various past, well-documented extreme events such as volcanic eruptions,
fires, anthropogenic pollution, and industrial accidents. We demonstrate
that the method is well suited to the detection of spectral signatures for reactive and weakly absorbing gases, even for sporadic events. Consistent long-term records are also generated for fire and volcanic events from the available IASI/Metop-B data record. The method is running continuously, delivering email alerts on a routine
basis, using the near-real-time IASI L1C radiance data. It is planned to be
used as an online tool for the early and automatic detection of extreme
events, which was not done before.