bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Ocean Acidification on Molting, Oxidative Stress, and Gut Microbiota in Juvenile Horseshoe Crab Tachypleus tridentatus
Authors: Liu Ximei , Liu Jiani , Xiong Kai , Zhang Caoqi , Fang James Kar-Hei , Song Jie , Tai Zongguang , Zhu Quangang , Hu Menghong , Wang Youji
Published: January 2022

Anthropogenic elevation of atmospheric carbon dioxide (CO2) drives global-scale ocean acidification (OA), which has aroused widespread concern for marine ecosystem health. The tri-spine horseshoe crab (HSC) Tachypleus tridentatus has been facing the threat of population depletion for decades, and the effects of OA on the physiology and microbiology of its early life stage are unclear. In this study, the 1st instar HSC larvae were exposed to acidified seawater (pH 7.3, pH 8.1 as control) for 28 days to determine the effects of OA on their growth, molting, oxidative stress, and gut microbiota. Results showed that there were no significant differences in growth index and molting rate between OA group and control group, but the chitinase activity, β-NAGase activity, and ecdysone content in OA group were significantly lower than those of the control group. Compared to the control group, reactive oxygen species (ROS) and malondialdehyde (MDA) contents in OA group were significantly increased at the end of the experiment. Superoxide dismutase (SOD), catalase (CAT), and alkaline phosphatase (AKP) activities increased first and then decreased, glutathione peroxidase (GPX) decreased first and then increased, and GST activity changed little during the experiment. According to the result of 16S rRNA sequencing of gut microbiota, microbial-mediated functions predicted by PICRUSt showed that “Hematopoietic cell lineage,” “Endocytosis,” “Staphylococcus aureus infection,” and “Shigellosis” pathways significantly increased in OA group. The above results indicate that OA had no significant effect on growth index and molting rate but interfered with the activity of chitinolytic enzymes and ecdysone expression of juvenile horseshoe crabs, and caused oxidative stress. In addition, OA had adverse effects on the immune defense function and intestinal health. The present study reveals the potential threat of OA to T. tridentatus population and lays a foundation for the further study of the physiological adaptation mechanism of juvenile horseshoe crabs to environmental change.
A Combination of Leaf Rust Resistance Genes, Including Lr34 and Lr46, Is the Key to the Durable Resistance of the Canadian Wheat Cultivar, Carberry
Authors: Bokore Firdissa E. , Knox Ron E. , Hiebert Colin W. , Cuthbert Richard D. , DePauw Ron M. , Meyer Brad , N’Diaye Amidou , Pozniak Curtis J. , McCallum Brent D.
Published: January 2022

The hexaploid spring wheat cultivar, Carberry, was registered in Canada in 2009, and has since been grown over an extensive area on the Canadian Prairies. Carberry has maintained a very high level of leaf rust (Puccinia triticina Eriks.) resistance since its release. To understand the genetic basis of Carberry’s leaf rust resistance, Carberry was crossed with the susceptible cultivar, Thatcher, and a doubled haploid (DH) population of 297 lines was generated. The DH population was evaluated for leaf rust in seven field environments at the adult plant stage. Seedling and adult plant resistance (APR) to multiple virulence phenotypes of P. triticina was evaluated on the parents and the progeny population in controlled greenhouse studies. The population was genotyped with the wheat 90 K iSelect single nucleotide polymorphism (SNP) array, and quantitative trait loci (QTL) analysis was performed. The analysis using field leaf rust response indicated that Carberry contributed nine QTL located on chromosomes 1B, 2B (2 loci), 2D, 4A, 4B, 5A, 5B, and 7D. The QTL located on 1B, 2B, 5B, and 7D chromosomes were observed in two or more environments, whereas the remainder were detected in single environments. The resistance on 1B, detected in five environments, was attributed to Lr46 and on 7D, detected in seven environments to Lr34. The first 2B QTL corresponded with the adult plant gene, Lr13, while the second QTL corresponded with Lr16. The seedling analysis showed that Carberry carries Lr2a, Lr16, and Lr23. Five epistatic effects were identified in the population, with synergistic interactions being observed for Lr34 with Lr46, Lr16, and Lr2a. The durable rust resistance of Carberry is attributed to Lr34 and Lr46 in combination with these other resistance genes, because the resistance has remained effective even though the P. triticina population has evolved virulent to Lr2a, Lr13, Lr16, and Lr23.
High-Density Single Nucleotide Polymorphisms Genetic Map Construction and Quantitative Trait Locus Mapping of Color-Related Traits of Purple Sweet Potato [Ipomoea batatas (L.) Lam.]
Authors: Yan Hui , Ma Meng , Ahmad Muhammad Qadir , Arisha Mohamed Hamed , Tang Wei , Li Chen , Zhang Yungang , Kou Meng , Wang Xin , Gao Runfei , Song Weihan , Li Zongyun , Li Qiang
Published: January 2022

Flesh color (FC), skin color (SC), and anthocyanin content (AC) are three important traits being used for commodity evaluation in purple-fleshed sweet potato. However, to date, only a few reports are available on the inheritance of these traits. In this study, we used a biparental mapping population of 274 F1 progeny generated from a cross between a dark purple-fleshed (Xuzishu8) and white-fleshed (Meiguohong) sweet potato variety for genetic analyses. Correlation analysis showed a significant positive correlation among AC, SC, and FC. Medium-to-high heritability was observed for these traits. We detected single nucleotide polymorphisms (SNPs) by specific length amplified fragment sequencing (SLAF-seq) with the average sequencing depth of 51.72 and 25.76 for parents and progeny, respectively. Then we constructed an integrated genetic map consisting of 15 linkage groups (LGS) of sweet potato spanning on 2,233.66 cm with an average map distance of 0.71 cm between adjacent markers. Based on the linkage map, ten major quantitative trait loci (QTLs) associated to FC, SC, and AC were identified on LG12 between 0 and 64.97 cm distance, such as one QTL for SC and FC, respectively, which explained 36.3 and 45.9% of phenotypic variation; eight QTLs for AC, which explained 10.5–28.5% of the variation. These major QTLs were highly consistent and co-localized on LG12. Positive correlation, high heritability, and co-localization of QTLs on the same LG group confirm the significance of this study to establish a marker-assisted breeding program for sweet potato improvement.
The Effect of Cognitive–Behavioral Play Therapy on Improvements in Expressive Linguistic Disorders of Bilingual Children
Authors: Rezaeerezvan Shahrzad , Kareshki Hossein , Pakdaman Majid
Published: January 2022

The present study attempted to investigate the effect of cognitive-behavioral play therapy (CBPT) on the improvements in the expressive linguistic disorders of bilingual children. The population consists of all bilingual children with expressive linguistic disorders studying in preschools. Considering the study’s objectives, a sample of 60 people, in three groups (experimental, control, and pseudo-control), were selected using WISC, TOLD, and clinical interviews. The experimental group members participated in CBPT training sessions. The training consisted of twelve 90-min sessions, three times per week programs held every other day. The pseudo-control group received training different from play therapy. The experimental group members were subjected to the follow-up test 2 months after the end of the intervention. All three groups sat the TOLD3 test before and after the experiment. Data analysis was carried out using ANCOVA. The results of data analysis suggested that CBPT can improve the expressive language disorders of bilingual children.
The Explanatory Effect of a Label: Its Influence on a Category Persists Even If We Forget the Label
Authors: Aslanov Ivan A. , Sudorgina Yulia V. , Kotov Alexey A.
Published: January 2022

In this study we replicated the explanatory effect of a label which had been found byGiffin et al. (2017). In their experiments, they used vignettes describing an odd behavior of a person based on culturally specific disorders that were unfamiliar to respondents. It turned out that explanations which explain an odd behavior through a person’s tendency to behave that way (circulus vitiosus) seemed more persuasive if the disorder was given a label that was used in the explanation. We replicated these results in Experiment 1, and in a follow-up Experiment 2 we examined the familiarity with category information and the evaluation of that category over time (the delay lasted one week). We realized that the label effect persists even when people make judgments based on their recollections about a category. Furthermore, according to a content analysis of the recollections, participants in the label condition remembered more information from the vignettes but tended to forget an artificial label; however, they used other words from the disorder domain instead (like “disease” or “kleptomania”). This allowed us to suggest a new interpretation of this effect: we suppose that in theGiffin et al. (2017)experiments the label did not bring any new features to a category itself, but pointed to a relevant domain instead, so the effect appeared from the activation of areas of knowledge in semantic memory and the application of relevant schema for learning a new phenomenon.
Early Word Order Usage in Preschool Mandarin-Speaking Typical Children and Children With Autism Spectrum Disorder: Influences of Caregiver Input?
Authors: Xu Ying Alice , Naigles Letitia R. , Su Yi Esther
Published: January 2022

This study explores the emergence and productivity of word order usage in Mandarin-speaking typically-developing (TD) children and children with autism spectrum disorder (ASD), and examines how this emergence relates to frequency of use in caregiver input. Forty-two caregiver-child dyads participated in video-recorded 30-min semi-structured play sessions. Eleven children with ASD were matched with 10 20-month-old TD children and another 11 children with ASD were matched with 10 26-month-old TD children, on expressive language. We report four major findings: (1) Preschool Mandarin-speaking children with ASD produced word order structures with pervasive ellipsis at similar rates to language-matched TD children, but also displayed differences from TD children in their usage of SVt and VtO frames; (2) Grammatical productivity was observed in both TD children and children with ASD; moreover, children with ASD with higher expressive language produced less stereotyped language; (3) Both TD children and children with ASD heard a range of word orders in their caregivers’ input, with TD children’s input greater in amount and complexity; however, caregivers of both groups also showed no age/language-related changes in word order usage; (4) Few word-order-specific correlations emerged between caregivers and their children; however, strong correlations were observed for mean length of utterances (MLU) for both groups: Caregivers who produced longer/more complex utterances had children who did the same. Taken together, it seems that despite their pragmatic deficits, the early grammatical knowledge of word order in Mandarin-exposed children with ASD is well preserved and in general follows the typical developmental pattern. Moreover, caregiver input is broadly rather than finely tuned to the linguistic development of TD children and children with ASD, and plays a more important role in children’s general syntactic development than in specific word order acquisition. Thus, early word order usage in preschool Mandarin-speaking TD children and children with ASD may be influenced by both caregiver input and child abilities.
Exploring the Relationship Between Value Modularity, Knowledge Transfer, and Firm Innovation Performance: Evidence From China
Authors: Wang Jianhua , Zhao Yan , Han Xiao , Li Luying , Rasool Samma Faiz
Published: January 2022

This study aimed to explore the influence the value modularity and a firm’s innovation performance, directly and indirectly, using knowledge management as mediating variable. Moreover, in this study, we used the resource integration ability as a moderator between the relationship value modularity and firm innovation performance. We collected data from the Chinese state-owned and state-controlled high-tech firms from 2011 to 2018. In this study, we used the gray comprehensive evaluation method to test the degree of value modularity, and hierarchical regression analysis is used to analyze the relationship among variables. The outcomes of this study indicate that value modularity and firm innovation performance has inverted U-shaped and significant association. Similarly, results also confirm that knowledge acquisition and knowledge internalization mediate the relationship between value modularity and firm innovation performance. The finding of this research also confirms that resource integration ability negatively affects the relationship between value modularity and firm innovation performance. This paper enriches the research of the value modularity and gives certain inspiration to knowledge management. At the end of this study, we also suggest some significant practical implications.
Impact of Perceived Supportive Learning Environment on Mathematical Achievement: The Mediating Roles of Autonomous Self-Regulation and Creative Thinking
Authors: Niu Weihua , Cheng Li , Duan Dana , Zhang Qingyang
Published: January 2022

A total of 1,281 Chinese students in grades 3–6 participated in a study that examined the relationships among student-perceived supportive learning environment (PSLE), mathematical achievement, autonomous self-regulation, and creative thinking. The results demonstrated that student PSLE is positively associated with autonomous self-regulation, creative thinking, and mathematical achievement. In addition, the study also demonstrated that the influence of PSLE on students’ mathematical achievements could be mediated through autonomous self-regulation and creative thinking, respectively. The results shed light on the effectiveness of a supportive learning environment on educational and psychological outcomes in Chinese mathematical classrooms.
Self-Regulation of Slippery Deadlines: The Role of Procrastination in Work Performance
Authors: Steel Piers , Taras Daphne , Ponak Allen , Kammeyer-Mueller John
Published: January 2022

We investigated the causes and impact of procrastination on “slippery deadlines,” where the due date is ill-defined and can be autonomously extended, using the unique applied setting of grievance arbitration across two studies. In Study One, using 3 years of observed performance data derived from Canadian arbitration cases and a survey of leading arbitrators, we examined the effect of individual differences, self-regulatory skills, workloads and task characteristics on time delay. Observed delay here is a critical criterion, where justice is emphasized to beswiftand sure. Multilevel Modeling established trait procrastination as a substantive predictor of observed delay, equivalent to the environmental contributors of expediting the arbitration procedure or grievance complexity. Also, despite substantive negative consequence of delay for both arbitrators and their clients, arbitrators who scored one standard deviation above the mean in procrastination took approximately 83 days to write their decisions compared to the 26 days for arbitrators one standard deviation below the mean. In Study Two, we conducted a replication and extension survey with a much larger group of American arbitrators. Consistent with Temporal Motivation Theory (TMT), trait procrastination was largely explained by expectancy, value, and sensitivity to time related traits and skills, which together accounted for majority of the variance in trait procrastination, leaving little left for other explanations. For example, perfectionism connection to procrastination appears to be distal, being largely mediated by each of TMT’s core variables. Finally, procrastination was largely synonymous with a deadline pacing style, indicating that observed delay can be used as a proxy for procrastination as long as little or no prior work was done (e.g., a u-shaped pacing style is not synonymous). In all, our results indicate that procrastination is rampant in the workplace and has seriously detrimental effects.
The Prevalence of Impulse Control Disorders and Behavioral Addictions in Eating Disorders: A Systematic Review and Meta-Analysis
Authors: Devoe Daniel J. , Anderson Alida , Bahji Anees , Singh Manya , Patten Scott B. , Soumbasis Andrea , Ramirez Pineda Ana , Flanagan Jordyn , Richardson Candice , Lange Tom , Dimitropoulos Gina , Paslakis Georgios
Published: January 2022

Aim: Individuals with eating disorders (EDs) may present with impulse control disorders (ICDs) and behavioral addictions (BAs), which may result in additional suffering and treatment resistance. However, the prevalence of ICDs and BAs in EDs has not been systematically examined. Therefore, this systematic review and meta-analysis aimed to assess the prevalence of ICDs and BAs in ED samples.

Methods: A comprehensive electronic database search of the peer-reviewed literature was conducted in the following online databases: MEDLINE, PsycINFO, Embase, and CINAHL from their inception to May 2021. We restricted review eligibility to research studies reporting prevalence for ICDs or BAs in individuals with diagnosed EDs. The outcome for this review was the prevalence of ICDs or BAs in individuals with EDs. A series of random-effects meta-analyses were performed on eligible studies to estimate the pooled proportions and 95% confidence intervals (CIs).

Results: Thirty-five studies met the inclusion criteria, including a total of 9,646 individuals identified as having an ED, 18 of these studies specifically examined ICDs/BAs in AN, BN, and BED. Random-effects pooled estimates demonstrated that the comorbid prevalence of any ICD was 22%. The prevalence of comorbid pathological/compulsive buying was highest (19%), followed by kleptomania (18%), pathological internet use (12%), intermittent explosive disorder (4%), trichotillomania (3%), and gambling disorder (2%). In addition, the prevalence of stealing/shoplifting behaviors was 30% in those with EDs.

Conclusion: This is the first meta-analysis on the comorbid prevalence of EDs and ICDs/BAs. We found a moderate prevalence for these comorbid conditions, with approximately one out of five individuals with an ED also displaying a comorbid ICD/BA. Although causal inferences cannot be drawn, the numbers strongly suggest that clinical screening/monitoring of ICDs/BAs should be part of the clinical routine in cohorts with EDs. ED settings need either the capacity to manage these disorders or adequate access to relevant services. Further investigations are needed to reveal common underlying pathomechanisms.

Systematic Review Registration:https://www.crd.york.ac.uk/prospero/, identifier: CRD42020202044.
Antidepressant Treatment-Induced State-Dependent Reconfiguration of Emotion Regulation Networks in Major Depressive Disorder
Authors: Zhao Lei , Wang Donglin , Xue Shao-Wei , Tan Zhonglin , Luo Hong , Wang Yan , Li Hanxiaoran , Pan Chenyuan , Fu Sufen , Hu Xiwen , Lan Zhihui , Xiao Yang , Kuai Changxiao
Published: January 2022

Deficits in emotion regulation are the main clinical features, common risk factors, and treatment-related targets for major depressive disorder (MDD). The neural bases of emotion regulation are moving beyond specific functions and emphasizing instead the integrative functions of spatially distributed brain areas that work together as large-scale brain networks, but it is still unclear whether the dynamic interactions among these emotion networks would be the target of clinical intervention for MDD. Data were collected from 70 MDD patients and 43 sex- and age-matched healthy controls. The dynamic functional connectivity (dFC) between emotion regions was estimated via a sliding-window method based on resting-state functional magnetic resonance imaging (R-fMRI). A k-means clustering method was applied to classify all time windows across all participants into several dFC states reflecting recurring functional interaction patterns among emotion regions over time. The results showed that four dFC states were identified in the emotion networks. Their alterations of state-related occurrence proportion were found in MDD and subsequently normalized following 12-week antidepressant treatment. Baseline strong dFC could predict the reduction rate of Hamilton Depression Rating Scale (HAMD) scores. These findings highlighted the state-dependent reconfiguration of emotion regulation networks in MDD patients owing to antidepressant treatment.
Prevalence and Correlates of Cardiovascular Calcification and Its Prognostic Effects Among Patients With Chronic Kidney Disease: Results From the C-STRIDE Study
Authors: Wang Lan , Cheng Hong , Zou Xinrong , Yuan Jun , Wu Wenjing , Han Siping , Wang Jinwei , Zhang Luxia , He Kevin , Zhao Ming-Hui , Wang Xiaoqin
Published: January 2022

Background and Aims: The purpose of this study was to identify the characteristics and risk factors for cardiovascular calcification, and its relationship to prognosis, in patients with chronic kidney disease (CKD) stages 1–4.

Methods: Cardiovascular calcification was evaluated at baseline by lateral abdominal radiography to detect abdominal aortic calcifications (AAC), and by echocardiogram to detect cardiac valvular calcifications (CVC), respectively. Demographic and laboratory data were collected and analyzed. Univariate and multivariable logistic regression model was used to explore the factors associated with the indicators of cardiovascular calcification, while Cox proportional hazards regression was used to examine the association between AAC/CVC and incidence of cardiovascular events and all-cause mortality.

Results: A subgroup of 2,235 patients with measurement of AAC in the C-STRIDE study and a subgroup of 2,756 patients with CVC were included in the analysis. AAC was present in 206 patients (9.22%) and CVC was present in 163 patients (5.91%). Age, gender, history of cardiovascular diseases, smoking, hypertension, diabetes, levels of hemoglobin, low-density lipoprotein cholesterol, and uric acid were associated with prevalence of AAC, while only age, history of cardiovascular diseases, levels of serum albumin and low-density lipoprotein cholesterol were associated with prevalence of CVC (all p < 0.05).Survival analyses showed that cardiovascular events and all-cause mortality were significantly greater in patients with AACor with CVC (all p-values for log-rank tests <0.05). After adjustment for age, sex and estimated glomerular filtration rate (eGFR), AAC was associated with increased risk of all-cause mortality (hazard ratio = 1.67[95% confidence interval: 0.99, 2.79]), while CVC associated with that of cardiovascular events only among patients with comparatively normal eGFR (≥45 ml/min/1.73m2) (hazard ratio = 1.99 [0.98, 4.03]).

Conclusion: Demographic and traditional cardiovascular risk factors were associated with cardiovascular calcification, especially AAC. AAC may be associated with risk of death for patients CKD of any severity, while CVC as a possible risk factor for cardiovascular disease only among those with mild to moderate CKD. Assessments of vascular calcification are need to be advanced to patients in the early and middle stages of chronic kidney disease and to initiate appropriate preventive measures earlier.
Two-Step Estimation of the Impact of Contextual Variables on Technical Efficiency of Hospitals: The Case Study of Public Hospitals in Iran
Authors: Mohamadi Efat , Kiani Mohammad Mehdi , Olyaeemanesh Alireza , Takian Amirhossein , Majdzadeh Reza , Hosseinzadeh Lotfi Farhad , Sharafi Hamid , Sajadi Haniye Sadat , Goodarzi Zahra , Noori Hekmat Somayeh
Published: January 2022

Background: Measuring the efficiency and productivity of hospitals is a key tool to cost contamination and management that is very important for any healthcare system for having an efficient system.

Objective: The purpose of this study is to examine the effects of contextual factors on hospital efficiency in Iranian public hospitals.

Methods: This was a quantitative and descriptive-analytical study conducted in two steps. First, we measured the efficiency score of teaching and non-teaching hospitals by using the Data Envelopment Analysis (DEA) method. Second, the relationship between efficiency score and contextual factors was analyzed. We used median statistics (first and third quarters) to describe the concentration and distribution of each variable in teaching and non-teaching hospitals, then the Wilcoxon test was used to compare them. The Spearman test was used to evaluate the correlation between the efficiency of hospitals and contextual variables (province area, province population, population density, and the number of beds per hospital).

Results: On average, the efficiency score in non-teaching hospitals in 31 provinces was 0.67 and for teaching hospitals was 0.54. Results showed that there is no significant relationship between the efficiency score and the number of hospitals in the provinces (p = 0.1 and 0.15, respectively). The relationship between the number of hospitals and the population of the province was significant and positive. Also, there was a positive relationship between the number of beds and the area of the province in both types of teaching and non-teaching hospitals.

Conclusion: Multilateral factors influence the efficiency of hospitals and to address hospital inefficiency multi-intervention packages focusing on the hospital and its context should be developed. It is necessary to pay attention to contextual factors and organizational architecture to improve efficiency.
One Soft Step: Bio-Inspired Artificial Muscle Mechanisms for Space Applications
Authors: Ashby Joseph , Rosset Samuel , Henke E.-F. Markus , Anderson Iain A.
Published: January 2022

Soft robots, devices with deformable bodies and powered by soft actuators, may fill a hitherto unexplored niche in outer space. All space-bound payloads are heavily limited in terms of mass and volume, due to the cost of launch and the size of spacecraft. Being constructed from stretchable materials allows many possibilities for compacting soft robots for launch and later deploying into a much larger volume, through folding, rolling, and inflation. This morphability can also be beneficial for adapting to operation in different environments, providing versatility, and robustness. To be truly soft, a robot must be powered by soft actuators. Dielectric elastomer transducers (DETs) offer many advantages as artificial muscles. They are lightweight, have a high work density, and are capable of artificial proprioception. Taking inspiration from nature, in particular the starfish podia, we present here bio-inspired inflatable DET actuators powering low-mass robots capable of performing complex motion that can be compacted to a fraction of their operating size.
A Practical Strain Sensor Based on Ecoflex/Overlapping Graphene/Ecoflex Sandwich Structures for Vocal Fold Vibration and Body Motion Monitoring
Authors: Fan Yanyan , Zhao Hongbin , Yang Yifan , Yang Yi , Ren Tianling , Tu Hailing
Published: January 2022

Graphene-based stretchable and flexible strain sensors are one of the promising “bridges” to the biomedical realm. However, enhancing graphene-based wearable strain sensors to meet the demand of high sensitivity, broad sensing range, and recoverable structure deformation simultaneously is still a great challenge. In this work, through structural design, we fabricated a simple Ecoflex/Overlapping Graphene/Ecoflex (EOGE) strain sensor by encapsulating a graphene sensing element on polymer Ecoflex substrates using a drop-casting method. The EOGE strain sensor can detect stretching with high sensitivity, a maximum gauge factor of 715 with a wide strain range up to 57%, and adequate reliability and stability over 1,000 cycles for stretching. Moreover, the EOGE strain sensor shows recoverable structure deformation, and the sensor has a steady response in the frequency disturbance test. The good property of the strain sensor is attributed to the resistance variation induced by the overlap and crack structure of graphene by structural design. The vibrations caused by sound and various body movements have been thoroughly detected, which exhibited that the EOGE strain sensor is a promising candidate for wearable biomedical electronic applications.
Contributions of Agroforestry Systems to Food Provisioning of Peasant Households: Conflicts and Synergies in Chiapas, Mexico
Authors: Soto-Pinto Lorena , Colmenares Sandra Escobar , Kanter Marina Benítez , Cruz Angelita López , Lugo Erin Estrada , Hernández Balente Herrera , Jiménez-Soto Estelí
Published: January 2022

Traditional agroforestry systems are widely recognized for their contributions to provisioning, support, regulation, and cultural services. However, because of the advancement of industrial agriculture and a corporative food system, peasants' food systems are rapidly undergoing transformation. We identify the contributions of four types of agroforestry systems (AFS)—shade cocoa agroforest, shade coffee agroforest, milpas and homegardens—to food provisioning in peasant families and discuss conflicts between traditional food systems and the contemporary industrial model of production and consumption confronted by peasants and semi-proletarian migrants. We carried out research in 17 peasant communities in Chiapas, Mexico, and conducted 97 semi-structured interviews and agroecological inventories with peasant families, and 15 interviews with semi-proletarian families laboring in shade-grown coffee plantations. Thirty-nine weekly food diaries were applied in two communities. We recorded 108 plant species belonging to 49 botanic families. These species play an important role as sources of carbohydrates, protein, vitamins, minerals, and fatty acids. Despite the extraordinary agrobiodiversity of peasant agroecosystems, peasant families (PF) are changing their AFS' structure, composition and functions due to the influence of agribusiness, global markets, and public policies that orient changes in production and marketing, which in turn devalue local food, agrobiodiversity, and knowledge. Changing perceptions regarding the value of “good food” vs. “food of the poor” and competition over land use between traditional and modern systems are driving changes in diet, food sources, and health of PF who are including industrialized foods in their diets, driving changes in consumption patterns and affecting human health. For semi-proletarian migrants laboring in coffee plantations, land access in and outside of the plantation and strengthening social networks could mean access to healthier and culturally appropriate foods. While peasants have historically responded to market and household needs, articulating both activities to satisfy family needs and provide income is limited. This work highlights the urgent need to acknowledge the non-monetary value of local foods, agrobiodiversity, local knowledge, community building, and the need to work towards securing land access for landless workers in Latin America.
What Farm Size Sustains a Living? Exploring Future Options to Attain a Living Income From Smallholder Farming in the East African Highlands
Authors: Marinus Wytze , Thuijsman Eva S. , van Wijk Mark T. , Descheemaeker Katrien , van de Ven Gerrie W. J. , Vanlauwe Bernard , Giller Ken E.
Published: January 2022

Smallholder farming in sub-Saharan Africa keeps many rural households trapped in a cycle of poor productivity and low incomes. Two options to reach a decent income include intensification of production and expansion of farm areas per household. In this study, we explore what is a “viable farm size,” i.e., the farm area that is required to attain a “living income,” which sustains a nutritious diet, housing, education and health care. We used survey data from three contrasting sites in the East African highlands—Nyando (Kenya), Rakai (Uganda), and Lushoto (Tanzania) to explore viable farm sizes in six scenarios. Starting from the baseline cropping system, we built scenarios by incrementally including intensified and re-configured cropping systems, income from livestock and off-farm sources. In the most conservative scenario (baseline cropping patterns and yields, minus basic input costs), viable farm areas were 3.6, 2.4, and 2.1 ha, for Nyando, Rakai, and Lushoto, respectively—whereas current median farm areas were just 0.8, 1.8, and 0.8 ha. Given the skewed distribution of current farm areas, only few of the households in the study sites (0, 27, and 4% for Nyando, Rakai, and Lushoto, respectively) were able to attain a living income. Raising baseline yields to 50% of the water-limited yields strongly reduced the land area needed to achieve a viable farm size, and thereby enabled 92% of the households in Rakai and 70% of the households in Lushoto to attain a living income on their existing farm areas. By contrast, intensification of crop production alone was insufficient in Nyando, although including income from livestock enabled the majority of households (73%) to attain a living income with current farm areas. These scenarios show that increasing farm area and/or intensifying production is required for smallholder farmers to attain a living income from farming. Obviously such changes would require considerable capital and labor investment, as well as land reform and alternative off-farm employment options for those who exit farming.
Assessment of Hydroxyethyl Starch (6% HES 130/0.4) Kidney Storage in Critically Ill Dogs: A Post-mortem Prospective Study
Authors: Adamik Katja-Nicole , Stoffel Michael H. , Tangermann Simone , de Breuyn Dietler Bettina , Stokar-Regenscheit Nadine
Published: January 2022

Objective: Intravenous hydroxyethyl starch (HES) solutions are potentially nephrotoxic due to rapid renal tissue uptake, subsequent osmotic nephrosis, and long-lasting intracellular storage. This study aimed to investigate the severity of intracellular storage of HES in renal tissue samples from critically ill dogs receiving 6% HES 130/0.4.

Materials and Methods: Fresh, post-mortem (<2 h after death) renal tissue samples were analyzed through histology, immunohistochemistry (HES 130/0.4-specific antibodies), and electron microscopy for the severity of renal tubular vacuolization (VAC), intravacuolar HES accumulation (ACC), and ultra-structure impairment. Moreover, we investigated the relationship between VAC or ACC grade and HES dose (mL/kg), duration of HES administration (h), and pre-HES plasma creatinine concentrations.

Results: Histology revealed that 2/20 dogs (10%) had no, 11/20 dogs (55%) had mild, 5/20 dogs (25%) had moderate, and 2/20 dogs (10%) had severe VAC. Immunohistochemistry revealed that 5/20 dogs (25%) had no, 6/20 dogs (30%) had mild, 7/20 dogs (35%) had moderate, and 2/20 dogs (10%) had severe ACC. Both changes were predominantly found in the distal tubular epithelium of mild and moderate cases, and all tubular segments were affected in severe cases. Seven of 20 dogs (35%) had osmotic nephrosis (ON). On electron microscopy, large granules with an electron-dense content were repeatedly detected in individual cells, mainly in the distal tubules. No correlation was found between cumulative HES dose or duration of HES administration and VAC grade, ACC grade, or presence/absence of ON.

Conclusion: A high percentage of dogs had renal tubular HES storage and one-third of dogs showed HES-induced ON. Short-term HES administration caused VAC and ACC, regardless of the dose or duration of administration. In contrast to previous studies, HES 130/0.4 deposits were mainly located in the renal distal tubule.
Association Between DCE-MRI Perfusion Histogram Parameters and EGFR and VEGF Expressions in Different Lauren Classifications of Advanced Gastric Cancer
Authors: Li Zhiheng , Zhao Zhenhua , Wang Chuchu , Wang Dandan , Mao Haijia , Liu Fang , Yang Ye , Tao Feng , Lu Zengxin
Published: January 2022

Objective: To investigate the correlations between dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) perfusion histogram parameters and vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) expressions in advanced gastric cancer (AGC).

Methods: This retrospective study included 80 pathologically confirmed patients with AGC who underwent DCE-MRI before surgery from February 2017 to May 2021. The DCE-MRI perfusion histogram parameters were calculated by Omni Kinetics software in four quantitative parameter maps. Immunohistochemical methods were used to detect VEGF and EGFR expressions and calculate the immunohistochemical score.

Results: VEGF expression was relatively lower in patients with intestinal-type AGC than those with diffuse-type AGC (p < 0.05). For VEGF, Receiver operating characteristics (ROC) curve analysis revealed that Quantile 90 of Ktrans, Meanvalue of Kep and Quantile 50 of Ve provided the perfect combination of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for distinguishing high and low VEGF expression, For EGFR, Skewness of Ktrans, Energy of Kep and Entropy of Vp provided the perfect combination of sensitivity, specificity, PPV and NPV for distinguishing high and low EGFR expression. Ktrans (Quantile 90, Entropy) showed the strongest correlation with VEGF and EGFR in patients with intestinal-type AGC (r = 0.854 and r = 0.627, respectively); Ktrans (Mean value, Entropy) had the strongest correlation with VEGF and EGFR in patients with diffuse-type AGC (r = 0.635 and 0.656, respectively).

Conclusion: DCE-MRI perfusion histogram parameters can serve as imaging biomarkers to reflect VEGF and EGFR expressions and estimate their difference in different Lauren classifications of AGC.
Control of Apple Replant Disease Using Mixed Cropping with Brassica juncea or Allium fistulosum
Authors: Zhao Lei , Wang Gongshuai , Liu Xin , Chen Xuesen , Shen Xiang , Yin Chengmiao , Mao Zhiquan
Published: January 2022

Evidence indicates that Allium and Brassica species which release bioactive compounds are widely used in bio-fumigation to suppress soil-borne diseases. However, the active molecules of such plant residues are easily volatilized. In this study, we conducted mixed cropping of the apple tree with Allium fistulosum or Brassica juncea; the results demonstrated that such mixed cropping significantly improved the growth of the grafted apple seedlings and alleviated apple replant disease (ARD) for two years. The terminal-restriction fragment length polymorphism profile results showed that the soil fungal community demonstrated distinct variation and diversity in terms of composition. A. fistulosum and B. juncea significantly improved the Margalef, Pielou, and Shannon indices. In addition, the analyses of clone libraries showed that A. fistulosum and B. juncea promoted the proliferation of antagonistic fungi such as Mortierella, Trichoderma, and Penicillium, and inhibited the proliferation of pathogens such as Fusarium. Fusarium. Proliferatum(F. proliferatum) was abundant in replanted soil and proved to be an aggressive pathogen of apple seedlings. Our findings thus indicate that apple tree mixed cropping with A. fistulosum and B. juncea was an effective long-term method for modifying the resident fungal community and alleviating ARD.
Effect of Oregano Oil and Cobalt Lactate on Sheep In Vitro Digestibility, Fermentation Characteristics and Rumen Microbial Community
Authors: Wang Zhengwen , Li Xiongxiong , Zhang Lingyun , Wu Jianping , Zhao Shengguo , Jiao Ting
Published: January 2022

The objective of this experiment was to evaluate the effect of different EOC (0.1425% cobalt lactate + 1.13% oregano essential oil + 98.7275% carrier) levels on in vitro rumen fermentation and microbial changes. Six EOC levels (treatments: 0 mg·L−1, CON; 50 mg·L−1, EOC1; 100 mg·L−1, EOC2; 400 mg·L−1, EOC3; 800 mg·L−1, EOC4 and 1500 mg·L−1, EOC5) were selected to be used to in vitro incubation. The in vitro dry matter digestibility (IVDMD), in vitro neutral detergent fiber digestibility (IVNDFD), in vitro acid detergent fiber digestibility (IVNDFD), pH, ammonia-nitrogen (NH3-N) concentration, total volatile fatty acid (TVFA) concentration and microbial protein (MCP) concentration were measured after 48 h incubation, after which the groups with significant nutrient digestibility and fermentation parameters were subjected to 16S rRNA sequencing. The results showed that the total gas production (GP) of the EOC5 group was higher than that of the other groups after 12 h of in vitro incubation. TVFA, NH3-N and MCP concentrations were also shown to be higher in group EOC5 than those in other groups (p < 0.05), while NH3-N and MCP concentrations in the EOC2 group were lower than those in other groups significantly (p < 0.05). The molar ratio of acetic acid decreased while the molar ratio of propionic acid increased after the addition of EOC. 16S rRNA sequencing revealed that the rumen microbiota was altered in response to adding EOC, especially for the EOC5 treatment, with firmicutes shown to be the most abundant (43.1%). The relative abundance of Rikenellaceae_RC9_gut_group was significantly lower, while the relative abundance of uncultured_bacterium_f_Muribaculaceae and Succiniclasticum was significantly higher in the EOC5 group than those in other groups (p < 0.05). Comprehensive analysis showed that EOC (1500 mg·L−1) could significantly increase gas production, alter sheep rumen fermentation parameters and microbiota composition.
Formation Control Technology of Fixed-Wing UAV Swarm Based on Distributed Ad Hoc Network
Authors: Suo Wenbo , Wang Mengyang , Zhang Dong , Qu Zhongjun , Yu Lei
Published: January 2022

The formation control technology of the unmanned aerial vehicle (UAV) swarm is a current research hotspot, and formation switching and formation obstacle avoidance are vital technologies. Aiming at the problem of formation control of fixed-wing UAVs in distributed ad hoc networks, this paper proposed a route-based formation switching and obstacle avoidance method. First, the consistency theory was used to design the UAV swarm formation control protocol. According to the agreement, the self-organized UAV swarm could obtain the formation waypoint according to the current position information, and then follow the corresponding rules to design the waypoint to fly around and arrive at the formation waypoint at the same time to achieve formation switching. Secondly, the formation of the obstacle avoidance channel was obtained by combining the geometric method and an intelligent path search algorithm. Then, the UAV swarm was divided into multiple smaller formations to achieve the formation obstacle avoidance. Finally, the abnormal conditions during the flight were handled. The simulation results showed that the formation control technology based on distributed ad hoc network was reliable and straightforward, easy to implement, robust in versatility, and helpful to deal with the communication anomalies and flight anomalies with variable topology.
Daily Atmospheric Circulation Patterns and Their Influence on Dry/Wet Events in Iran
Authors: Ghassabi Zahra , Fattahi Ebrahim , Habibi Maral
Published: January 2022

Analyzing atmospheric circulation patterns characterize prevailing weather in a region. The method of principal component analysis and clustering was used to classify daily atmospheric circulation patterns. The average daily geopotential height of 500 hPa with 0.5° resolution of the ECMWF (1990–2019) were extracted from the Middle East. The S array was used to identify air types, and k-means clustering was used to classify daily air types. All days were divided into eighteen groups. Then, the surface maps and moisture flux divergence at the 850-hPa level of each pattern were studied. The, the connection between circulation patterns and precipitation occurrence is investigated by the PI index. The existence of a variety of precipitation and temperature regimes and consequent dry/wet periods is related to the type and frequency of the circulation patterns. In patterns with south to southwesterly currents, the low-pressure surface center extends from the south of the Red Sea to southern Turkey and is associated with the mid-level trough, where the moisture fluxes converge in the south of the Red Sea, southwest/south of Iran, and east of the Mediterranean Sea. Therefore, according to the intensity of the patterns, the most precipitation falls in the country’s western half, and the Zagros Mountain’s wind side. With the eastward movement of the Cyclonic patterns, the rainfall area extends to the eastern half of the country. With the pattern that the thermal low surface pressure extends to 35 °N latitude and is associated with the mid-level subtropical high, almost no rain occurs in the country.
Effects of Evaporative Emissions Control Measurements on Ozone Concentrations in Brazil
Authors: Ibarra-Espinosa Sergio , Freitas Edmilson Dias de , Andrade Maria de Fátima , Landulfo Eduardo
Published: January 2022

In this work, the possible benefits obtained due to the implementation of evaporative emissions control measures, originating from vehicle fueling processes, on ozone concentrations are verified. The measures studied are: (1) control at the moment when the tank trucks supply the fuel to the gas stations (Stage 1); (2) control at the moment when the vehicles are refueled at the gas stations, through a device installed in the pumps (Stage 2); (3) same as the previous control, but through a device installed in the vehicles (ORVR). The effects of these procedures were analyzed using numerical modeling with the VEIN and WRF/Chem models for a base case in 2018 and different emission scenarios, both in 2018 and 2031. The results obtained for 2018 show that the implementation of Stages 1 and 2 would reduce HCNM emissions by 47.96%, with a consequent reduction of 19.9% in the average concentrations of tropospheric ozone. For 2031, the greatest reductions in ozone concentrations were obtained with the scenario without ORVR, and with Stage 1 and Stage 2 (64.65% reduction in HCNM emissions and 31.93% in ozone), followed by the scenario with ORVR and with Stage 1 and Stage 2 (64.39% reduction in HCNM emissions and 32.98% in ozone concentrations).
Air Quality Measurements in Kitchener, Ontario, Canada Using Multisensor Mini Monitoring Stations
Authors: Mohammed Wisam , Shantz Nicole , Neil Lucas , Townend Tom , Adamescu Adrian , Al-Abadleh Hind A.
Published: January 2022

The Region of Waterloo is the third fastest growing region in Southern Ontario in Canada with a population of 619,000 as of 2019. However, only one air quality monitoring station, located in a city park in Kitchener, Ontario, is currently being used to assess the air quality of the region. In September 2020, a network of AQMesh Multisensor Mini Monitoring Stations (pods) were installed near elementary schools in Kitchener located near different types of emission source. Data analysis using a custom-made long-distance scaling software showed that the levels of nitrogen oxides (NO and NO2), ground level ozone (O3), and fine particulate matter (PM2.5) were traffic related. These pollutants were used to calculate the Air Quality Health Index-Plus (AQHI+) at each location, highlighting the inability of the provincial air quality monitoring station to detect hotspot areas in the city. The case study presented here quantified the impact of the 2021 summer wildfires on the local air quality at a high time resolution (15-min). The findings in this article show that these multisensor pods are a viable alternative to expensive research-grade equipment. The results highlight the need for networks of local scale air quality measurements, particularly in fast-growing cities in Canada.