bluuebunny/crossref_metadata_2025 huggingface dataset:
Histidine modified Fe3O4 nanoparticles improving the ethanol yield and tolerance of Saccharomyces cerevisiae
Authors: Qiao Cailin , Yang Suping , Ma Yi , Wen Li , Chu Chengxiang , Luo Huibo , Luo Xiaogang , Huo Danqun , Hou Changjun
Published: November 2023

Saccharomyces cerevisiae is the primary microorganism involved in
ethanol production. Nonetheless, the buildup of ethanol inhibits yeast
cell proliferation, consequently diminishing ethanol production. In this
study, we applied histidine-modified Fe3O4 nanoparticles (His-Fe3O4) for
the first time, to the best of our knowledge, as a means of enhancing
ethanol yield during the S. cerevisiae fermentation process. The results
demonstrated that exposing S. cerevisiae cells to Fe3O4 nanoparticles
(Fe3O4 NPs) led to increased cell proliferation and glucose consumption.
Furthermore, the introduction of His-Fe3O4 significantly boosted ethanol
content by 17.3% (p < 0.05) during fermentation. Subsequent
findings indicated that the rise in ethanol content correlated with
enhanced ethanol tolerance and improved efficiency of electron
transport. This study verified the favorable impacts of His-Fe3O4 on S.
cerevisiae cells and proposed a versatile, straightforward approach for
enhancing ethanol production in S. cerevisiae fermentation. This
enhancement is achieved through the mediation of improved ethanol
tolerance, promising substantial potential in the fermentation and
bioenergy sector.
The First Record of Leucism in the Rhabdophis tigrinus (Boie, 1826) (Squamata, Colubridae) in South Korea
Authors: Park Seung-Min , Cheon Seung-Ju , Park Hye-Rin , Kim Na-Yeong , Rahman Md Mizanur , Sung Ha-Cheol
Published: November 2023

Leucism, in which pigmentation is lost over part or the entire body of
an animal, has a range of possible genetic causes. Here, we report
leucism in an individual tiger keelback (Rhabdophis tigrinus) found on
Jeung Island, Shinan-gun, Jeollanam-do, South Korea, during a survey of
the distribution of reptiles in the area. The individual was observed
sunbathing in the bushes next to a pond. This individual exhibited
ecdysis, thus it considered that have normal feeding activity. Our
report represents the first observation of leucism in R. tigrinus, and
thus, further analysis is needed of this phenotype to more clearly
understand its impact on the species and its natural history.
The importance of worldwide linguistic and cultural diversity for climate change resilience
Authors: Couee Ivan
Published: November 2023

Local minority languages and dialects, through the local knowledge and
expertise associated with them, can play major roles in analyzing
climate change and biodiversity loss, in facilitating community
awareness of environmental crises and in setting up locally-adapted
resilience and sustainability strategies. While the situation and
contribution of deeply-rooted Indigenous Peoples are of emblematic
importance, the issue of the relationships between cultural and
linguistic diversity and environmental awareness and protection does not
solely concern peripheral highly-specialized communities in specific
ecosystems of the Global South, but constitutes a worldwide challenge,
throughout all of the countries, whatever their geographical location,
their economical development, or their political status. Environmental
emergency and climate change resilience should therefore raise
international awareness on the need to promote the survival and
development of minority languages and dialects and to take into account
their creativity and expertise in relation with the dynamics of their
local environments.
Lipidomic and transcriptomic analysis of the increase in eicosapentaenoic acid under cobalamin deficiency of Schizochytrium sp.
Authors: dongsheng Guo , Yang Linhui , Liu Mengzhen , Chen Zilei , Tong LingLing
Published: November 2023

Schizochytrium sp. is a heterotrophic microorganism capable of
accumulating polyunsaturated fatty acids, and has achieved industrial
production of docosahexaenoic acid (DHA). It also has the potential for
eicosapentaenoic acid (EPA) production. In this study, it was found that
the cell growth, lipid synthesis and fatty acid composition of
Schizochytrium sp. were significantly affected by the level of cobalamin
in the medium, especially with regards to the content of EPA in the
fatty acids. The content of EPA in the fatty acids increased 17.91
times, reaching 12.0%, but cell growth and lipid synthesis were
significantly inhibited under cobalamin deficiency. The response
mechanism for this phenomenon was revealed through combined lipidomic
and transcriptomic analysis. Although cell growth was inhibited under
cobalamin deficiency, the genes encoding key enzymes in central carbon
metabolism were still up-regulated to provide precursors (Acetyl-CoA)
and reducing power (NADPH) for the synthesis and accumulation of fatty
acids. Moreover, the main lipid subclasses observed during cobalamin
deficiency were glycerolipids (including glycerophospholipids), with EPA
primarily distributed in them. The genes involved in the biosynthesis of
these lipid subclasses were significantly up-regulated, such as the key
enzymes in the Kennedy pathway for the synthesis of triglycerides. Thus,
this study provided insights into the specific response of
Schizochytrium sp. to cobalamin deficiency and identified a subset of
new genes that can be engineered for modification.
Effect of collection tubes on synovial fluid bacterial culture.
Authors: Rihuete Pablo Jimenez , Martin Carolynn , Villarino Nicolas , Martinez Luis M. Rubio
Published: November 2023

Introduction Silica sprayed tubes (SST) are often used to transport
synovial fluid samples in equine practice. They promote coagulation of
the sample. The objective of the study is to evaluate the effect of SST
on bacterial culture. Materials & methods The study was divided into
two parts: sterile saline (Part A), and synovial fluid (Part B). Four
common bacteria associated with equine synovial sepsis were used:
Streptococcus pyogenes, Escherichia coli, Staphylococcus aureus, and
methicillin-resistant Staphylococcus aureus. Three collection-tubes were
used: STT, plain (No-additives) and brain & heart infusion (BHI) broth.
Bacteria were cultured in horse blood agar plates for 48h. Outcome
variables were negative culture, positive culture, and total number of
forming colony units (FCU). Statistical analysis was performed using
Mann-Whitney U test, significance was set at p< 0.05. Results
The total number of agar plates read was 1557. Total negative cultures
were 24/779 on saline and 3/778 on synovial fluid. In broth maximum
growth FCU was achieved after 8h for both saline and synovial fluid for
all bacteria. Streptococcus pyogenes and Escherichia coli produced a
significantly lower number of FCU when in SST compared to plain or broth
after 4h. Staphylococcus aureus (ATCC & MRSA) only after 24h.
Discussion Silica containing tubes reduced bacterial proliferation,
whilst the use of a BHI broth provided the highest bacterial burden in
the sample. Use of SST may have a negative effect on bacterial
proliferation in samples obtained from clinical cases.
Long‑term effectiveness of three anti‑CGRP monoclonal antibodies in resistant migraine patients: a real-world study
Authors: López EDUARDO Pons-Fuster , Lozano Obdulia , Valbuena Sebastian Martín , Lucas Cesar , Mancebo Almudena , Gorostiza Ignacio De , Ponce Celia Maria Gonzalez
Published: November 2023

Aim: To assess the long-term effectiveness, clinical predictors, safety,
and treatment persistence of three anti-CGRP mAbs (erenumab,
galcanezumab, fremanezumab) in RM patients. Methods: A single-center
retrospective study was conducted from December 2019 to June 2023
involving 126 RM patients who received anti-CGRP mAbs treatment for at
least 6 months. Demographic and clinical data were collected, and
assessments were conducted at 6, 12, and 24 months. Effectiveness was
evaluated using clinical burden parameters, acute medication usage, and
monthly migraine days (MMD). Patients achieving a ≥ 50% reduction in
MMD were classified as responders, and baseline parameters and logistic
regression between groups were analyzed. Adverse effects and treatment
discontinuation were documented. Results: Treatment with anti-CGRP mAbs
led to significant reductions in disability, MMD and acute medication
usage, with sustained improvements observed up to 24 months. Responders
exhibited lower baseline MMD and medication overuse. Medication overuse
was identified as a negative predictor of treatment efficacy. Safety
profiles were favorable, with few adverse events and minimal treatment
discontinuations. Conclusion: Anti-CGRP mAbs prove effective in reducing
migraine-related disability and headache frequency in RM patients over a
24-month period with favorable safety profiles. However, controlled
studies with larger populations are warranted for further validation.
Hepcidin as a biomarker of neonatal infections
Authors: Predojevic-Samardzic Jelica , Malcic-Zanic Dragana , Eric Zelimir , Guzijan Gordana , Samardzic Sergej
Published: November 2023

Introduction/Objective. Nonspecific clinical signs of neonatal infection dictate routinely determination of C-reactive protein (CRP) and procalcitonin levels in order to confirm the diagnosis. As hepcidin is an acute phase reactant, the aim of our study was to analyze its significance in diagnosis of neonatal infections. Methods. The prospective study included 71 term neonates, 37 with signs of infection in the absence of other pathological conditions and 34 healthy neonates. After standard bacteriological examination, at the time of diagnosis and after six days of antibiotic therapy, complete blood count, serum CRP, procalcitonin, and hepcidin were determined. Results. There was no difference in serum hepcidin levels between the control (55.17 ? 21.22 ng/ml) and the infection group (59.72 ? 59.7 ng/ml) on the first day. Hepcidin values in neonates with infection up to 72 hours were significantly lower (30.2 ng/ml, IQ: 25.9?39.9 ng/ml) than in older neonates (82.2 ng/ml, IQ: 39.7?128.1 ng/ml). In neonates up to 72 hours, after six days of antibiotics, the hepcidin values show a significant increase (36.68 ng/ml, IQ; 31.23?50.3 ng/ml). High hepcidin values (128.05 ng/ml, IQ: 60.95?201 ng/ml) were recorded in neonates with CRP over 100 mg/l. Conclusion. Our results shows that the determination of serum hepcidin as a marker of neonatal infection is not relevant in neonates up to 72 hours of life. After six days of antibiotic therapy, the neonates of this group reacted with an increase in hepcidin, while the parallel determined values of CRP and procalcitonin showed a significant decrease.
Optical coherent tomography with angiography in glaucoma
Authors: Marjanovic Ivan , Maric Vesna , Bozic Marija
Published: November 2023

Optical coherence tomography with angiography (OCT-A) is a non-invasive imaging technique that enables three-dimensional visualization of perfusion through the vascular network of the retina and choroid. The possibilities of OCT-A for glaucomatologists will expand in the near future. The possibility of detecting and monitoring glaucoma with this technology will also be expanded. All of these systems will undoubtedly offer software updates, making it easier for examiners to use the device itself, and thus monitor the disease. OCT-A represents the future in the diagnosis of retinal diseases and glaucoma.
Comparative Study on the Oil Content and Fatty Acids Profile among Some Brassica rapa L. Genotypes
Authors: Shelly N. J. , Bhuiyan M. S. R. , Rahman J. , Zamil S. S. , Sumon M. M.
Published: November 2023

The study was carried out at Biochemistry, Agricultural Chemistry and Environmental Science laboratory of Sher-e-Bangla Agricultural University, Dhaka, Bangladesh from March, 2020 to September, 2021 to estimate oil content and fatty acids composition of some Brassica rapa L. genotypes. The experiment was laid out in a completely randomized design with three replications and consisted of four genotypes viz., BARI Sarisha-14, Brown Special, Yellow Special, Tori-7 and their F1s. Result revealed that the oil content ranged from 34.25-45.05% among the studied genotypes. The parent, Yellow Special contained the highest amount of oil (45.05%) and Brown Special contained the lowest amount (39.48%), while among the F1s, (Brown Special×Yellow Special) contained the highest amount (39.04%) and (BARI Sar-14×Brown Special) contained the lowest amount (34.25%). The major saturated and unsaturated fatty acids content ranged from 3.92-5.42% and 92.39-93.50% respectively. The parent, Brown Special and the F1- (BARI Sar-14×Brown Special) contained the highest amount of unsaturated fatty acids (92.81%) and (93.50%) respectively, while the parent Yellow Special and the F1- (Brown Special×Tori-7) contained the lowest amount of saturated fatty acids (3.96%) and (3.92%) respectively. The highest poly unsaturated fatty acids containing parent was Tori-7 (16.98%) and F1 was Yellow Special×Tori-7 (19.27%). The erucic acid content ranged from 44.97- 54.56%. Among the parents, Tori-7 and among the F1s-Yellow Special×Tori-7 contained the lowest amount of erucic acid (44.97%) and (45.37%) respectively. Therefore, the parents and F1s with high level of poly unsaturated fatty acids and low level of erucic acid could be selected for further development of these trait.
Transfer Pricing System of EU Countries: An Analysis in the Context of SDGS
Authors:   Assistant Professor, Department of Accounting and Audit, Faculty of Accounting and Management Information Systems, Bucharest University of Economic Studies, Bucharest, Romania, IGNAT Ioana , TACHE Marta ,   Position, Department of Accounting and Audit, Faculty of Accounting and Management Information Systems, Bucharest University of Economic Studies, Bucharest, Romania
Published: November 2023

"Considering that the base erosion and the profit shifting practiced by multinationals could deprive governments of their fair share in taxes and, as a consequence of the financial resources needed to achieve the sustainable development goals (‘SDGs’), governments have started to be interested in the implementation of transfer pricing regulations. The objective of the paper is to analyze the transfer pricing regulations and practices adopted by the EU countries that record a good progress in terms of SDGs vs. EU countries that record a moderate progress in this respect. The results of the study show that the strictness of the transfer pricing system influences the progress regarding the achievement of the SDGs. More exactly, the countries which record a good progress in achieving SDGs have, in general, a stricter transfer pricing system. In order to increase the strictness of the transfer pricing system and the progress in terms of SDGs, countries could implement regulation which envisage: the preparation of an annual transfer pricing documentation; the preparation of a documentation on three levels according to BEPS 13; the adoption of certain measures in order to increase the number of APAs, MAPs and transfer pricing audits; imposing of penalties."
Impact, Utilization and Applications of Digital Media for Government in Rural Settings. A Comparative US-Romania Research
Authors:   Executive director, James M. Cox Jr. Center for International Mass Communication Training and Research, Grady College of Journalism and Mass Communication, University of Georgia, Athens, United States of America, VLAD Tudor , HINȚEA Cristina ,   Associate professor, Public Administration and Management Department, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania, NEAMȚU Bogdana ,   Associate professor, Public Administration and Management Department, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania, STĂNICĂ Viorel ,   Associate professor, Public Administration and Management Department, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania
Published: November 2023

This paper aims to answer the call for studies o Interaction between citizens and government has traditionally taken place in community settings, government meetings, special town hall meetings, written correspondence in letters, emails, or texts, or via a phone call to a government representative. With digital media, citizens can instantly interact with the government. The mobile component of digital media will continue to be important in this interaction. This research operates with the assumption that digital media expresses a paradigmatic shift regarding how to govern and how to communicate. Digital media clearly is transforming the way governments think, plan, and carry out their policies but more importantly, how they communicate public policy. Our research intends to understand how local government institutions in rural settings use digital media and other communication channels to communicate with their citizens. The research employs a comparative perspective by investigating rural communities from the US and Romania. This was achieved by undertaking a content analysis of local government’s websites and social media platforms, as well as collecting primary data through interviews with representatives of local government, to assess the ways they use digital media, traditional media, and other communication tools, and whether they viewed them as effective strategies.
Diuretic Effect of Combination of Watercress (Nasturtium officinale) and Purslane (Portulaca oleraceae)
Authors: Sutjiatmo Afifah Bambang , Yuliartati Ni Luh Ade , Yulianti Maulidya , Suryani Suryani , Vikasari Suci Nar
Published: November 2023

Watercress (Nasturtium officinale) and purslane (Portulaca oleracea) are used to increase urination.This preclinical study aims to prove the diuretic effect of a combination of watercress and purslaneextracts. Simplisia of watercress and purslane herbs mixed with various combinations A (1:9), B(1:3) and C (1:1), then extracted in 50% ethanol. The animals were divided into five groups: control,furosemide 3.6 mg/kgBW, A 38 mg/kgBW, B 28 mg/kgBW, and C 10 mg/kgBW. Diuretic assay wascarried out using the modified Lipschitz method with the parameters observed were cumulative urinevolume for 6 and 24 hours, and potassium levels in 24-hour urine. The results showed the onset ofdiuretic effect of furosemide at 60 minutes, A at 150 minutes, B at 240 minutes and C at 90 minutes.Percent effectiveness of the diuretic in the furosemide was 718%, A 212%, B 231%, and C 368% whencompared to the controls. All combinations of extracts increased sodium and potassium secretion whencompared to controls, but this effect was not as strong as furosemide. All combinations of watercressand purslane herbs have a diuretic effect but weakly saluretic when compared to furosemide and thecombination that gives the best effect is combination C.
Production of Anti-Recombinant Human Insulin Antibody and Validation by Indirect ELISA
Authors: Ambarsari Christy , Suryadi Herman , Yanuar Arry
Published: November 2023

Human insulin potential has become an interest and is important in maintaining the success of therapyin patients with the availability of chemical-based analytical methods, however, only a few have beenusing immunoassays. This study aimed to produce IgG polyclonal antibodies from rabbits immunizedwith 1 mg/mL rhINS subcutaneously and validated by indirect ELISA. Antibody was precipitated andfractioned on a HiTrap® Protein A HP column before being quantified with a UV spectrophotometerat λ 280 nm. The characterization was conducted by Dot Blot test on a BCIP-NBT substrate, as well asSDS-PAGE and Western Blot with polyacrylamide gel concentrations of 7.5% and 17.5%. Validationwas performed using solutions containing glycerol and m-cresol as matrices spiked with rhINS. Thelinearity test in the rhINS concentration range of 80.11-200.28 μg/mL (r = 0.99) showed the linearresult. The accuracy and precision obtained an average of 99.11%±5.01 and 3.91%, while the LODand LOQ were 22.05 μg/mL and 73.51 μg/mL, respectively. Human insulin was stable at 2-8oC for 24hours (α: 0.05, ANOVA). In conclusion, in-house produced IgG polyclonal antibodies and goat anti-IgG peroxidase conjugate can be used for routine testing of human insulin.
The role of B vitamins in the development and progression of age-related macular degeneration
Authors: Figurska Małgorzata
Published: November 2023

In recent years, the importance of B vitamins as biologically active nutrients with potential effects preventing the development and progression of age-related macular degeneration has been analysed. This work is a review of the current literature from the last 10 years, dealing with the subject of the properties of B vitamins and research providing epidemiological data on its intake and plasma concentration and their impact on the disease in patients with macular degeneration.
The review confirms the important beneficial role of B vitamins in limiting the development and progression of macular degeneration. Although further randomized trials are needed to evaluate diet and determine selected plasma antioxidants over a longer, at least several years’ period while taking into account pokara number of risk factors for modifiable and determine selected plasma antioxidants over a longer, at least several years’ period while taking into account a number of risk factors for modifiable and non-modifiable macular degeneration.
Development strategies for reducing infant mortality: A focus on healthcare infrastructure and policy in emerging Asian countries
Authors: Sriyanto Sriyanto , Khalil Luqman , Naseem Imran , Nassani Abdelmohsen A. , Binsaeed Rima H. , Zaman Khalid , Salamun Hailan , Haffar Mohamed
Published: November 2023

The journey towards better healthcare sustainability in Asian nations demands a comprehensive investigation into the impact of urban governance, poverty, and female literacy on infant mortality rates. This study undertakes a rigorous exploration of these key factors to pave the way for evidence-based policy interventions, utilizing data from a panel of six selected Asian countries: Pakistan, China, India, Indonesia, Malaysia, and the Philippines, spanning the years 2001 to 2020. The findings reveal that adequate sanitation facilities, higher female literacy rates, and sustained economic growth contribute to a reduction in infant mortality. Conversely, increased poverty levels and limited women’s autonomy exacerbate the infant mortality rates observed in these countries. The Granger causality analysis validates the reciprocal relationship between urban sanitation (and poverty) and infant mortality rates. Furthermore, the study establishes a causal relationship where female literacy rates Granger-cause infant mortality rates, and conversely, infant mortality rates Granger-cause women’s autonomy in these countries. The variance decomposition analysis indicates that sustained economic growth, improved female literacy rates, and enhanced women’s empowerment will likely impact infant mortality rates in the coming decade. Consequently, in low-income regions where numerous children face potentially hazardous circumstances, it is imperative to allocate resources towards establishing and maintaining accessible fundamental knowledge regarding sanitation services, as this will aid in reducing infant mortality rates.
Job Protection — It is Good to be an Insider
Authors: Gebauer Markus
Published: November 2023

This study develops a search and matching model for labour markets with temporary and permanent contracts. It matches empirical patterns of higher matching rates and lower surplus for temporary workers and predicts an increase in separation taxes leads to a fall in the number of new permanent jobs, an increase in their wages, and stable separation rates because temporary workers shield permanent workers from adverse shocks. We find empirical support using a regional French policy experiment, the “Contrat de Transition Professionelle”, which increased separation taxes for recently hired permanent workers in firms with fewer than 1,000 workers.
The Impact of Personality Traits on Turnover Intention: The Mediating Effect of Job Insecurity
Authors: ALAYLI Sahar
Published: November 2023

Previous literature has acknowledged that it is essential to examine how employees’ personality traits affect employment outcomes, particularly disparities in job performance. This study investigates the mediating effect of job insecurity on the individual's personality traits and turnover intention. The questionnaires were collected online between March and April of the same year. In addition, the study's intended audience included entry-level and mid-level workers. The survey was circulated using Google Forms, emails, and social media to gather the data. As a result of the questionnaires being distributed among the participants, the study took a snowball approach. This study also uses a sample size of 299 employees (N=299). Job Insecurity would mediate between Big Five personality characteristics and turnover intention, which would have a detrimental impact on employees' willingness to leave their jobs. It was shown that the Big Five personality qualities adversely predicted turnover intention, while job insecurity mediates the relationship between the Big Five personality traits and turnover intention. For Thai employees who voluntarily quit, traits such as affected feelings, toughness of mind, and shyness were found to be predictive of leaving; commitment was found to be associated with turnover intentions for low self-monitors, and external locus of control was found to be associated with intentions to leave.
Public Entrepreneurship: A Literature Review
Authors: BIRU Engida , ZEWDIE Shimels
Published: November 2023

In many writings the concept of entrepreneurship is frequently associated with the private sector, and with small and medium sized enterprises, and start-ups. However, the public sector also frequently participates in entrepreneurial action, sometimes providing some of the most important services for the economy. Nowadays, the issue of Public Entrepreneurship need to get more attention by researchers, academicians and practitioners, especially in developing countries like Ethiopia. Because it helps to create value for the citizens of a state by bringing together unique combinations of public and/or private resources to exploit social opportunities, and provides many more advantages. At a minimum, public entrepreneurship involves the production, distribution, or innovation of goods/ services for the public. This makes it crucial to the lives of billions of people around the world. For example, entrepreneurial initiatives by public entities include the provision of health care services, water services, emergency services, transportation, and recycling/climate initiatives, among others. The purpose of this review work was to develop a literature review on the mission, key characteristics, types of public entrepreneurship, difference between public and private sector entrepreneurship, and public entrepreneurship strategy to overcome public sector barriers to entrepreneurship and come up with pertinent points. So, to carry on this review work, only 69 articles were chosen based on the inclusion and exclusion criteria of the reviewer.
Leveraging Opportunities for Public Sector Digitalisation: A Macroeconomic Analysis
Authors: CICEA Claudiu , SIMION Cezar Petre , MARINESCU Corina
Published: November 2023

The aim of this study is to explain from an econometric point of view, the relationship between digitalisation in the public domain and opportunities in the environment of public sector organisations. The analysis is carried out on a set of 29 European countries, and the EU-27 average, on a specific period of time. The panel data regression analysis reveals both positive and negative relationships, as well as direct and indirect connections between variables of interest. After presenting the regression results, one can conclude that changes in the level of opportunities may influence changes in the digitisation process at the level of each country included in the analysis. Six hypotheses were tested by the econometric model. Among them, only one has been validated for 26 out of 30 cases. It is the one testing the positive link between digitisation in the public sector and the way the Internet is being used, respectively, for goods and services search activities.
Managing the Dynamics of the US Gas and Oil Market: An In-depth Analysis
Authors: GRASU Stelian
Published: November 2023

The United States of America (US) has long been a key player in the global energy landscape, with its gas and oil market serving as a critical component of both its domestic economy and international relations. This paper provides a comprehensive overview of the US's gas and oil market, analysing its historical evolution, current state, and prospects. The paper begins by tracing the historical developments that have shaped the US's gas and oil industry, including key milestones such as the discovery of major oil fields, the growth of shale gas production, and the impact of geopolitical events on market dynamics. It then delves into the contemporary landscape, examining the major players in the industry, production and consumption trends, infrastructure, and distribution networks, as well as the regulatory frameworks that govern exploration, extraction, and trade. In this article, the author tries to make an overview of the US gas and oil market from the market from its appearance until today. The gas and oil market legislation and the authorities that regulate and supervise the market are identified and presented. The federal and states transport and distribution system is an overview and their connection. This article also offers a comprehensive analysis of the US gas and oil market, encompassing its historical trajectory, current landscape, economic significance, environmental challenges, and future directions. By examining these facets, it will be provided valuable insights into the complex interplay between energy resources, economic development, and environmental sustainability within the context of a rapidly evolving global energy landscape.
Children's Use of Everyday Mathematical Concepts to Describe, Argue and Negotiate Order of Turn
Authors: Bevemyr Mats
Published: November 2023

In this paper expressions that children themselves use to describe relationships between phenomena in the world, is - when placing a mathematical gaze on them- viewed as everyday mathematical concepts. The aim of the paper is to illuminate children´s use of everyday mathematics in their social interaction. More specifically, the aim is to show in detail how four- to five-year-olds use everyday mathematical concepts to describe, argue and negotiate order of turn, in this case in their interaction around a computer at a Swedish preschool. The case study is based on five 4 to 5 year old children´s activities involving a computer at a municipal preschool in Sweden. The children´s interaction around the computer was video recorded and analyzed in detail from a participant-oriented perspective on interactional conduct. The analysis shows that the children use various expressions that can be interpreted as everyday mathematical concepts as communicative cultural tools in their social interaction. Furthermore, the results show that the children have actual use for these concepts in their argumentation for order of turn, and that the concepts they use seem to be most sufficient in their argumentation in this situated activity. A conclusion is that the everyday mathematical concepts used in the analyzed activity can form a foundation for developing more formal mathematical concepts.
Wood Residue of Jatobá (Hymenaea courbaril) and Short Fiber of Malva in Composites
Authors: Da Costa Deibson Silva , Banna Wassim Raja El , Fujiyama Roberto Tetsuo
Published: November 2023

Theoretical reference: The composites are formed by combining two or more materials, enabling improvements in properties and a variety of applications. These materials are highlighted by presenting low cost and enabling environmentally friendly alternatives.
 
Method: Quantitative study, In this work, composites of polyester matrix reinforced by mauve fibers, jatoba wood residues and hybrid mauve/residue system, were analyzed mechanically and microstructurally. The fabrication of the composites began with the cut of the mauve fibers in the lengths of 5, 10 and 15 mm. In the manufacture of the specimens, terephthalic polyester resin was used with incorporation of fibers and residue. The specimens were produced in silicone molds, for the tensile strength tests and scanning electron microscopy (SEM) analysis.
 
Results and conclusion: From the results obtained in the tensile test, it is observed that the resistance of the composites with mauve fibers of 15 mm (25,09 MPa) and hybrids in the proportions of 75% fiber/25% residue (26,06 MPa). In the microstructural characterization, the composites analyzed presented factors that contributed to the improvement and reduction of performance in the results of tensile strength.
 
Implications of the research: It presents important and overwhelming results on composite materials with wood waste and mallow fibers, providing an alternative for inserting waste and fibers into materials with good properties and low cost.
 
Originality/value: The compounds stand out for their simple and viable manufacturing method, in addition to superior results in relation to proven properties. Given the need to search for new materials with good properties and with minimal impacts on the environment.
REKLAMASI PANTAI DITINJAU DARI UNDANG-UNDANG NOMOR 1 TAHUN 2014 TENTANG PENGELOLAAN WILAYAH PESISIR DAN PULAU PULAU KECIL
Authors: Sodik Miftahol Fajar
Published: November 2023

The beauty of nature and all geological ecosystems is a gift from Almighty God which was created for humanity as subjects to manage, use and be responsible for preserving all the beauty of the third planet called Earth, so that all living creatures that inhabit that place can live in mutualistic symbiosis. Irresponsible use and exploitation of natural resources is a threat in living together so that it is not uncommon to find land dredging, conversion of functions and even beach reclamation which can result in natural disasters and imbalance in the geological ecosystem. In this journal, we will explain how legal provisions (formal juridical) protect and regulate the use of natural resources in contact with oceans and beaches, so in this case the author uses an approach and study method of applicable legal rules (positive law) by explaining the contents of the law. -laws that regulate the extent of legal protection for the use of nature in a civil society.
STATUS KEWARGANEGARAAN ANAK SEBELUM ADANYA UNDANG-UNDANG KEWARGANEGARAAN NO. 12 TAHUN 2006 TENTANG KEWARGANEGARAAN
Authors: Handayani Pristika , Giyono Urip
Published: November 2023

The purpose of this paper is to analyze normatively regarding children resulting from marriages of different citizens, which in this case is regulated in law number 12 of 2006 concerning citizenship. Children from mixed marriages have the right to determine or choose citizenship. In the case of a child's citizenship, it can be obtained after the child is 18 (eighteen) years old. Children can determine their own citizens because they are considered adults in accordance with the provisions stipulated in the Civil Code. With the regulations governing citizenship, it is hoped that later there will be no unrest for children, and also children's rights will be maintained, especially in terms of administration in Indonesia.
Trace element composition of zircon from granitoids of the Neoarchean alkaline province of the Kola Peninsula
Authors: Vetrin V. R. , Skublov S. G.
Published: November 2023

Research subject. Zircon from granitoids of the A- and I-types of the Neorchean Kola alkaline province of the Baltic (Fennoscandian) shield. Aim. To determine the trace element composition of zircon in order to characterize the conditions of its formation in different types of granitoids. To use these data, along with the available results of U-Pb dating and Lu-Hf isotope composition of the studied zircon crystals, to assess the amount of mantle and core matter in the protolith composition and the effect of crystallization conditions on the rare element composition of zircon. Materials and Methods. 50 zircon crystals from 5 samples of the main types of granitoids of the province were studied. Concentrations of trace elements were determined using a Cameca IMS-4f ion microprobe (NF FTIAN, Yaroslavl). Points for analysis were selected using optical and cathodoluminescent images. The size of the crater did not exceed 20 µm, the relative measurement error for the predominant part of the elements was set at 10–15%, the threshold for detecting elements was 10 ppb. Results. There are two main types of zircon of Neoarchean age – zircon-1 and zircon-2, formed, respectively, at the magmatic and autometasomatic stages of crystallization, zircon-4 in inclusions in zircon-1, and Paleoproterozoic zircon-3 of metamorphic genesis. The average isotopic composition of Hf in zircon-1 and zircon-2 of different arrays varies slightly, with the amount of mantle component (Xm) ranging from 23 to 30%, which may indicate a relatively constant and significantly core composition of their protoliths. Conclusions. The change in the trace element composition of Neoarchean zircons was controlled mainly by the composition of protoliths and redox crystallization conditions. Under reducing conditions, the greatest chemical activity was acquired by light (La-Nd) lanthanides, for which a direct dependence on the Ce/Ce* value was established. For heavy lanthanides with similar ion sizes relative to Zr+4, crystallochemical factors were more important and a decrease in the dependence of heavy lanthanide concentrations in zircon on Ce/ Ce* was determined.
دور إدارة الموارد البشرية الرقمية في تحقيق التحول الرقمي دراسة إستطلاعية لآراء عينة من القيادات الإدارية والأكاديمية في جامعة دهوك
Authors: Hussein Ali Blani Zaid , Qasim Hussein Sinan
Published: November 2023

يًعد مجال التعليم من أهم المجالات التي تُبنى عليها الأمم والمجتمعات وتتطور من خلالها الدول والحضارات، وفي ظل التطورات التكنولوجية وظهور الوسائل والأجهزة والتقنيات الحديثة، تأثرت بها جميع المجالات وجوانب الحياة واخترقت هذه التطورات قلب منظومة المجتمع، إذ أثرت هذه التغيرات والتطورات على الجامعات بشكل عام؛ لكون الجامعة تُعتبر البنية التحتية والركيزة التي تستند عليها المجالات الأخرى، فلابد لها من تبني التطورات الحديثة قبل الجميع، ومن هذه النقلات التكنولوجية هو التحول الرقمي واستخدام الوسائل والأجهزة الرقمية والتي أجبرت الجامعات الخاصة والعامة سواء إلى إحداث تغييرات وتعديلات في مهارات وقدرات مواردها البشرية وكذلك الهياكل والتقنيات والإجراءات التي تقوم بها بالشكل الذي ينسجم مع التطورات السريعة والتكيف مع بيئة العمل المتقلبة والمتغيرة بشكل سريع، ومن المعلوم بأن تطبيق التحول الرقمي يحتاج إلى موارد بشرية مؤهلة وذات خبرة كافية للقيام بتلك العمليات والإشراف عليها والتحول من إستخدام الطرق والأساليب التقليدية إلى الإجراءات الرقمية الحديثة، لذلك تحتاج الجامعة إلى إدارة مواردها البشرية بشكل رقمي لمواكبة تلك التطورات،
        ويهدف البحث الحالي إلى إستطلاع آراء عينة من القيادات الإدارية والأكاديمية في جامعة دهوك وكلياتها ومن خلال عينة بلغت (73) فرداً تجاه متغيرات البحث عن طريق إستمارة الإستبيان والتي تم تحليل بياناتها باعتماد (الحزمة الإحصائية للعلوم الإجتماعية – SPSS/V26). وأسفرت نتائج البحث عن أن إدارة الموارد البشرية الرقمية والتحول الرقمي يتم تطبيقها بدرجة متوسطة في الجامعة المبحوثة ولكن دون مستويات الطموح في ظل الطفرة التكنولوجية والتطورات السريعة الحاصلة في جميع المجالات، إذ أنه كلما زاد اعتماد الجامعة المبحوثة والكليات التابعة لها على إدارة الموارد البشرية الرقمية، فإنها ستكون قادرة على تحقيق التحول الرقمي بمستويات عالية. كما وقدم البحث عدداً من المقترحات منها قيام الجامعة المبحوثة بتوفير برامج تدريبية وورش عمل وندوات للقيادات التي تمتلكها بهدف توضيح أهمية إدارة الموارد البشرية الرقمية والفوائد التي ستجنيها الجامعة عند القيام بتطبيق هذا النهج والعمل على برامج وخطط تساعدها في توفير متطلبات التحول الرقمي والإعتماد عليها بشكل أكبر.
الوضع القانوني لمراكز البحث العلمي في الدول النامية دراسة تحليلية
Authors: Sabri Ismail Najdat
Published: November 2023

تتناول الدراسة تحليلاً لمراكز البحث العلمي بشكل عام من حيث التعريف العام بها عبر بيان مفهومها و نماذج منها و من ثم دراسة الوضع القانوني لمراكز البحث العلمي من حيث الاليات القانونية لعملها و الاشكاليات القانونية التي تعاني منها و بالتالي تأثيرات ذلك على مديات دورها في منظومة البحث العلمي لهذه الدول التي هي بحاجة ماسة اليها مع بيان المقترحات الكفيلة بتحقيق نجاحها.
A person was raped, who is the agent?
Authors: Laplante Marianne , Dupuy Alexandra , Nault Spencer
Published: November 2023

This paper focuses on media coverage of cases of sexual assault committed by public figures in the Québec cultural landscape who were publicly accused by their victims over the course of two #MeToo movements. We consider the four cases of: Gilbert Rozon, Éric Salvail, Julien Lacroix, and Maripier Morin. While the former two cases have been to court, the latter two have not. We are interested in how the media talk about the sexual assaults committed, specifically the lexical items and patterns of syntactic agency, depending on whether the case was prosecuted or not. Our data consist of the headline and first paragraph of articles published about the cases in three influential francophone newspapers in Québec. We argue that the media coverage of the sexual assault cases analyzed reinforces the ideology that sexual assaults in prosecuted cases are more credible and severe than those that are not prosecuted in court.
Spoken language bilingualism for deaf students
Authors: Simpson Melanie
Published: November 2023

Language has always been at the core of our practice in deaf education, but in the current context, it is time to explore new language possibilities for deaf students. Over the past two decades, the combination of widespread implementation of universal newborn hearing screening (UNHS) and early amplification with hearing technologies, including cochlear implants (CIs), has afforded meaningful access to spoken language during the critical language development period for most deaf children. Early interventionists and educators have taken a new perspective of encouraging spoken language bilingualism in home languages and the majority language. This shift has opened doors to education in spoken language bilingual settings (e.g., French immersion), doors formerly closed to deaf students. This paper presents some preliminary qualitative data, highlighting parent decision-making, from a mixed method case study of deaf Francophone participants (N = 4) enrolled in grades 4-12 at French minority schools in southern Ontario.
Indigenous Incarceration in Canada
Authors: MacCarthy Liam
Published: November 2023

Canadian sentencing law reform in 1996 and the R. v. Gladue 1999 Supreme Court landmark decision, Canada introduced an internationally unique requirement for Canadian courts in sentencing Indigenous offenders to give special consideration to systemic factors in order to address the historic and ongoing experiences of Indigenous people in the criminal justice system Canada. While these reforms to the criminal justice system were centred around alleviating the egregious level of incarcerated Indigenous people, this analysis will reveal the implementation of Gladue principles has not been the transformative change many have hoped for. This Canadian policy research paper argues that the Canadian government’s Gladue policy has been underfunded and requires a commitment to the complete implementation of Gladue Reports and Gladue Courts to accomplish its objectives of considering the systemic circumstances of Indigenous offenders and providing criminal justice in a culturally appropriate manner.
Public Sector Contribution to Vaccine Research and Development
Authors: Brown Ella
Published: November 2023

This paper explores the public sector’s often undersold role in vaccine research and development (R&D). Further, it examines the recent shift in vaccine innovation policy caused by the urgency of the COVID-19 pandemic. Due to factors such as lack of repetitive dosage, high levels of at-risk investment, and long, large clinical trials, it is difficult to incentivize the private sector to invest in vaccine R&D. To counter these difficulties, vaccine innovation policy focuses on both push and pull incentives to ensure vaccine R&D is proceeding. Government institutions make large at-risk investments to offset the risk for private sector investment into vaccine R&D. Additionally, the government creates innovation policies that make intellectual property rights (IPR) more favourable for those who invest in vaccine R&D. With the removal of IPR for COVID-19 vaccines, the public sector became more instrumental in incentivizing private sector investment, using techniques such as mass ex-ante government vaccine procurement agreements, public-private partnerships, and increased government investments. With more significant government investments in downstream development and manufacturing activities, there is concern that the basic scientific research required for advances in vaccine technology will diminish. With the COVID-19 pandemic still unfolding, it is difficult to determine whether vaccine innovation policy will remain as it is now. However, even if vaccine innovation policy shifts post-pandemic, the public sector must continue to play an important role in vaccine R&D.
Numerical Investigation of the Dynamic Instability of a Reentry Capsule in Transonic Flow
Authors: Han Seoeum , Lee Bok Jik , Ahn Furudate Michiko , Nagai Hiroki
Published: November 2023

This study presents a numerical investigation of transonic flow characteristics over a reentry capsule at Mach 1.05, employing a detached eddy simulation. The simulated flowfields demonstrate that the recompression shock wave oscillates back and forth at a Strouhal number of the order of 0.01. Frequency analysis of fluctuations in the drag coefficient and base pressure reveals that these fluctuations can be predominantly attributed to oscillations in the recompression shock wave. While the recompression shock wave propagates upstream, local shock waves occur alternately in the upper and lower free-shear layers, with a Strouhal number of the order 0.1, due to the instability of free-shear layers. The repeated occurrence of these local shock waves causes the recirculation region to shrink, resulting in a decrease in the base pressure. Conversely, while the recompression shock wave propagates downstream, no local shock wave occurs and the recirculation region expands, leading to an increase in the base pressure. These results suggest that the interactions among the recompression shock wave, local shock wave, and free shear layer give rise to fluctuations in the base pressure of the capsule, which in turn can affect its dynamic instability.
EFFECT OF THE SP-D GENE ON HSP70 SYNTHESIS IN MACROPHAGES AFTER REPROGRAMMING
Authors:   Yevdokimov Moscow State University of Medicine and Dentistry, Lyamina S.V. , Kalish S.V. ,   Research Institute for Systems Biology and Medicine, Moscow
Published: November 2023

Based on the data of significant Sp-D effect on the local immune response in the lungs and its extrapulmonary effects, we expect the SP-D effect on the systemic immune and inflammatory response. The effect of SP-D on the synthesis of stress proteins and testing the hypothesis of the phenotype-dependence of these effects for macrophages, key cells of the innate immunity system is of particular interest.
STIMULATION OF HUMAN DERMAL FIBROBLASTS CHONDROGENIC DIFFERENTIATION FOR TISSUE ENGINEERING OF HYALINE CARTILAGE
Authors:   Institute of Cytology RAS, Saint Petersburg, Marchenko D.M. , Bozhokin M.S. , Mikhailova E.R. , Sopova Yu.V. , Khotin M.G. ,   Vreden National Medical Research Centre of Traumatology and Orthopedics, Saint Petersburg,   Saint Petersburg State University,   Vavilov Institute of General Genetics RAS, Saint Petersburg
Published: November 2023

This work is devoted to the possibility of human dermal fibroblasts chondrogenic differentiation using the TGF-β3 and SOX9 recombinant proteins and lentiviral vectors carrying sequences of the Tgf-β3 and Sox9 genes. It has been shown that the use of the TGF-β3 protein and vector with the Sox9 gene makes it possible to increase the expression of associated with chondrogenesis genes in fibroblasts.