bluuebunny/crossref_metadata_2025 huggingface dataset:
Um brinde a Saussure e Bakhtin com licor de piqui - Volume 2
Authors: Benassi Claudio Alves
Published: September 2023

A presente coletânea tem como principal finalidade, dar visibilidade aos resultados do projeto de pesquisa “Estudos filosóficos herméticos da língua(gem): práticas textuais discursivas e registros de língua Libras e reminiscências das línguas ioruba e banto em terreiros”, obtidos na atual fase dos estudos desenvolvidos pelo grupo de estudos. Esse grupo reúne estudantes e pesquisadores em torno de dois eixos teóricos: a linguística saussuriana, a teoria enunciativa de Bakhtin e a filosofia clássica e hermética. Assim, apresenta-se capítulos de autoria dos membros do grupo de estudo nessas duas vertentes pesquisadas, durante o período que compreende os meses entre maio de 2022 e maio de 2023.
ENSINO E APRENDIZAGEM DE LIBRAS COMO SEGUNDA LÍNGUA PARA OUVINTES: UMA ANÁLISE DIALÓGICA A PARTIR DE UMA VIDEOAULA NA PLATAFORMA YOUTUBE
Authors: Leite Franciele de Jesus Ferreira , Benassi Claudio Alves
Published: September 2023

A presente pesquisa pretende destacar uma possibilidade de construção de conhecimento acerca de Libras enquanto segunda língua para ouvintes falantes da língua portuguesa ao mesmo tempo que aprendizes básicos de uma língua de modalidade visuoespacial. Para isso, selecionamos uma videoaula na plataforma YouTube que estivesse em consonância com uma aula de Libras cujas premissas se distanciassem de mostra de sinal de um grupo semântico para repetição pelo aprendiz, mas que estivesse voltada para a dinamicidade da língua em contexto de uso real. Dessa maneira, elencamos os construtos bakhtinianos acerca da língua e linguagem de forma a nortear a construção analítica acerca dos enunciados presentes na videoaula. Assim, concluímos que, tal como as línguas orais-auditivas, a língua de sinais será melhor assimilada a partir de sua relação com fenômenos e eventos cotidianos.

Palavras-chave: Ensino-aprendizagem. Libras. Dialogismo.
Anti-angiogenic and oxidative effects of brilliant blue at different concentrations in chorioallantoic membrane model
Authors: Sozen Mehmet Enes , Savas Hasan Basri , Kucuk Mehmet Fatih , Dinc Elina
Published: September 2023

Introduction: Artificial food colorings are increasingly used to make the color and appearance of foods more attractive. One commonly used food dye is E133, international-coded brilliant blue (BB). According to the European Food Safety Authority panel results in 2010, it was determined that BB daily remained below the acceptable daily intake (ADI) value for adults and exceeded ADI value for children. The purpose of this study was to investigate the effects of BB on angiogenesis and oxidative stress in the chorioallantoic membrane model.

Materials & methods: In this investigation, fertilized chick eggs free of specific pathogens were used. The eggs that were not fully grown or fertilized were excluded. 50 embryos were distributed into five groups of 10 each. The negative control group was the control group, the positive control group was the bevacizumab group, and three different BB dosages (10-4 M, 10-5 M, and 10-6 M) were identified. At the end of the experiment, anti-angiogenesis scoring, and total antioxidant-oxidant capacity were evaluated.

Results: According to the average score values, the control group had no anti-angiogenic impact, but the bevacizumab group had a strong anti-angiogenic effect (average score 1.1). Furthermore, the 10-4 M BB group had a weak anti-angiogenic impact (average score of 0.7), while the 10-5 M and 10-6 M BB groups had no anti-angiogenic effect (average score of 0.4 and 0.2, respectively). As a result of one-way analysis of variance test, it was seen that BB significantly increased total oxidant capacity and oxidative stress index values in proportion to the increase in dose (p<0.05).

Conclusions: BB’s oxidant and anti-angiogenic effects indicate that high doses of processed foods containing artificial food dyes carry a risk for viable growth. Since there are not enough studies in the literature showing the oxidant or antiangiogenic effects of BB in chorioallantoic membrane model, the original data we presented in this study are pioneering.
Full-Service Carrier (FSC) vs Low-Cost Carrier (LCC): Purchasing Decision-Making Process of Passengers
Authors: KARAAĞAOĞLU Nuran , GÜNDÜZ Şafak
Published: September 2023

The demand for the aviation industry has grown as a result of the shift in people's travel preferences brought on by rising wealth and expanding trade in the world and in our nation. Air travel is now preferred due to state assistance, new airports, superior aircraft, and the relative drop in expenses. This study's main focus is on the consumer purchase patterns of two airline companies that operate in the very competitive aviation sector. Depending on whether the airline is a full-service carrier or a low-cost carrier, these variables change. The "Factors Affecting Airline Preferences Scale" was created and distributed to passengers of two airline organizations at Istanbul Sabiha Gökçen Airport (a full-service carrier (FSC) and a low-cost carrier (LCC) operating in Turkey) to assess the extent to which variables like airline reputation, advertising, frequent flyer programs, price, service quality, and digital marketing tools like websites, e-mails, Facebook, Twitter, Instagram, YouTube, and mobile applications have an impact on the process of ticket purchasing decision of passengers. It was shown that the passengers' purchasing decisions were influenced by reputation, service quality, frequent flyer programs, price, digital marketing initiatives, and advertisement. It was shown that depending on whether the airline is a full-service carrier or a low-cost carrier, the impact of these elements differs.
Esaretten Hetmanlığa: Yuriy Hmelnıtskı (1641-1685)
Authors: ŞEN Muhammet
Published: September 2023

Öz

Çok uzun bir geçmişe dayanan Türk- Ukrayna (Kozak) ilişkileri, tarih boyunca inişli-çıkışlı bir seyir göstermiştir. Bohdan Hmelnıtskıy’in hetmanlık döneminde (1648-1657) akim kalan Osmanlı-Kozak yakınlaşması, Petro Doroşenko’nun (1665-1676) hetmanlık döneminde Ukrayna Kozaklarının Osmanlı tabiliğine girmesiyle neticelenmiştir. Söz konusu bu tabilik Osmanlı Devleti’ni, Ukrayna toprakları hakimiyet mücadelesinde üçüncü bir güç olarak Polonya ve Rusya ile karşı karşıya getirmiştir. Petro Doroşenko’nun Rusya safına geçmesi (1676), Osmanlı Devleti’nin hem Ukrayna Kozakları üzerindeki otoritesinin sarsılmasına hem de mücadele halinde bulunduğu rakipleri Polonya ve Rusya’nın gerisinde kalmasına neden olmuştur. Hetman Petro Doroşenko’dan sonra Osmanlı Devleti, Hetman Bohdan Hmelnıtskıy’in oğlu Yuriy Hmelnıtskıy’i hetman tayin ederek, Kozaklar üzerindeki otoritesini tekrar tesis etmek istemiştir.

Bu çalışmada; Yuriy Hmelnıtskıy’ın Osmanlı Devleti’ne esir düşüp rehin olarak tutulmasına kadar olan siyasi yaşamı ele alınacak ve hangi konjektürel nedenlerle Osmanlı Devleti tarafından hetman tayin edildiğine değinilecektir. Nihayetinde Osmanlı Devleti hizmetinde bir hetman olarak yürütmüş olduğu siyasi faaliyetleriyle, Osmanlı Devleti’nin beklentilerini karşılayıp karşılayamadığı hususu, neden ve sonuçlarıyla değerlendirilecektir.

Anahtar Kelimeler: Osmanlı Devleti, Ukrayna Kozakları, Rusya, Bohdan Hmelnıtskıy, Yuriy Hmelnıtskıy.

From Captıvıty To Hetman: Yurii Khmelnitsky (1641-1685)

Abstract

Turkish-Ukrainian (Cossacks) relations, which have a very long history, have shown an up-and-down course throughout history. The Ottoman- Cossack rapprochement, which failed during the hetmanate of Bogdan Khmelnytsky (1648-1657), resulted in the subordination of the Ukrainian Cossacks to the Ottoman Empire during the hetmanate of Petro Doroshenko (1665-1676). This subordination brought the Ottoman Empire face to face with Poland and Russia as a third power in the struggle for dominance over the Ukrainian lands. Petro Doroshenko's defection to the Russian side (1676) caused the Ottoman Empire to lose its authority over the Ukrainian Cossacks and to fall behind its rivals Poland and Russia. After hetman Petro Doroshenko, the Ottoman Empire wanted to re-establish its authority over the Cossacks by appointing Yurii Khmelnitsky, the son of hetman Bogdan Khmelnitsky, as hetman.

In this study, the political life of Yurii Khmelnytskyi until he was captured by the Ottoman Empire and held as a hostage will be analysed and the conjectural reasons for his appointment as a hetman by the Ottoman Empire will be discussed. Finally, the political activities he carried out as a hetman in the service of the Ottoman Empire and whether he was able to meet the expectations of the Ottoman Empire will be evaluated with its causes and consequences.

Keywords: Ottoman Empire, Ukrainian Cossacks, Russia, Bogdan Khmelnitsky, Yurii Khmelnitsky.
Political Parties and Their Leaders’ Public Perception against Background of Current Psychological State of Russian Society
Authors: Shestopal E.B.
Published: September 2023

The article is devoted to the images of the Russian parties and their leaders against the background of the changes in the psychological state of our society in the modern conditions. The study was based on qualitative and quantitative research conducted in late 2022 — early 2023 in 22 regions. The object of the study were five parties represented in the State Duma (United Russia, The Communist Party of the Russian Federation, The Liberal Democratic Party, A Just Russia — For Truth, New People) and their leaders (A.Turchak, G.Zyuganov, V.Zhirinovsky, L.Slutsky, S.Mironov, and A.Nechaev). The research methodology included a survey, an in-depth interview, a semantic differential, a projective test, and a directed associations method. The study was not representative of the country as a whole, but the sample was balanced in terms of gender, age and education. The study demonstrated that the high level of anxiety and concerns of citizens about military actions did not affect a number of perception parameters, such as the attitude towards parties as a necessary part of the democratic process, the lack of a clear ideological identification of parties, and the personification of party images. At the same time, some parameters have undergone a significant transformation. First, the perception of a position of parties within the framework of the dichotomy “power — opposition” has changed. The Communist Party of the Russian Federation, A Just Russia — For Truth and The Liberal Democratic Party have lost a significant part of their image as opposition in the perception of citizens, while support for United Russia, which is clearly associated with the authorities, has increased. Second, the popularity of a flamboyant style has become a thing of the past, and today the image of the centrist party is the most attractive for voters. The new political reality requires that parties work to consolidate the society in the face of an external threat rather than demonstrate their independence and distance themselves from the authorities. Third, if before the beginning of the 2020s the demand for conservatism prevailed in the society, in the current situation social democratic and liberal values are more in demand.
Influence of Political Islam Factor in Modern World
Authors: Nisnevich Yu.A.
Published: September 2023

The article is devoted to the problem of the influence of the factor of political Islam in the modern conditions. In order to reveal such influence, the author examines the situation in 45 UN member stat es, where more than 50% of the population adheres to Islam, tentatively subdividing these states into Islamic, quasi-Islamic and secular. His analysis shows that the influence of the factor of political Islam in the field of politics of the Muslim world, and, consequently, in the global political space, is limited. The direct impact of political Islam on political processes is visible only in 12 Islamic states with stable political regimes and secular Turkey. In all these states, except for theocratic Islamic dictatorships Afghanistan and Iran, as well as Qatar, the authorities severely suppress any manifestations of radical political Islam. The interreligious Sunni-Shia conflict exerts a significant impact on the political situation in a number of Islamic states. In 20 quasi-Islamic and secular Muslim states with stable political regimes, political Islam, if present, is only on the periphery of the political field. At the same time, in some of the states in this group, the authorities have to fight cross-border terrorist activity of radical Islamic organizations. In almost a quarter of the states of the Muslim world, the political situation is currently unstable. Herewith, one of the factors of political turbulence in these states, along with ethnic and clan conflicts, is the terrorist activities of both international and national radical Islamic groups and movements.
Baron Is Dead — Long Live Baronet (Political Mediation on the Border of Empty and Filled Space)
Authors: Bliakher L.E. , Grigorichev K.V. , Kovalevsky A.V.
Published: September 2023

Based on a series of expeditions to the northern area of the Irkutsk region, the article examines the process of the formation of a special kind of quasi-political actors, denoted in the text by the term “taiga baronet”. These actors emerge under the conditions when, as a result of the “optimization” of the structures responsible for collecting information about social space, the latter, from the point of view of authorities, becomes “empty”. Along with the array of interpretable markers of the filled space, a number of operators capable of interpreting them decreases and at the end disappears. As a result, the government turns out to be blind, physically deprived of the ability to perform managerial functions. At the same time, having become invisible to the eye of the authorities, this space retains itself as an administratively and politically structured territory, in which representatives of local authorities are forced to carry out the activities prescribed to them and legally assigned to them. Due to the “blindness” of the authorities, this activity inevitably turns into an imitation. The problem, however, is that the space that the authorities perceive as “empty” still have residents, for whom this space remains both social and “filled,” and who continue to expect from government institutions that they provide a certain amount of public goods. Thus, a conflict arises, manifested in complaints, appeals to law enforcement agencies and higher authorities, which poses a threat to the favorable picture drawn in the reports. It is the need to somehow neutralize this threat that gives rise to the need for an agent who is not bound by the restrictions associated with the authorities’ view and is able to focus on the “here and now” situation, without universal standards. This agent not only assumes a number of functions of the local government, but also acts as a universal mediator between the “empty” and “filled” space, between the local community and the state structure.
Antifungal activity of silver nanoparticles loaded oregano oil nano-emulsion for topical treatment of mucocutaneous candidiasis
Authors: Divyangna Sonker  , Arvind kumar Srivastava  , Suman Jaiswal  , Alok Mukerjee
Published: September 2023

Oregano essential oil (OEO) possesses antimicrobial, antioxidant, and preservative properties, making it a promising candidate for various biotechnological and biomedical applications. However, the inherent volatility, hydrophobicity, and susceptibility to external factors such as light, heat, and oxygen can compromise its stability and bioactivity. To overcome these limitations, silver nanoparticles (AgNPs) were incorporated into an oregano oil nanoemulsion, enhancing both its antimicrobial efficacy and mechanical properties. Chronic Mucocutaneous candidiasis, often associated with recurrent unexplained fungal infections, is characterized by inherited T-cell defects and typically requires prolonged antifungal treatment. The approved oral imidazole derivative, ketoconazole, is commonly used for the treatment of candidiasis, chronic Mucocutaneous candidiasis, and oral thrush. However, non-compliance, therapy failure, and systemic side effects have been reported with prolonged use of ketoconazole. In this study, we developed a silver nanoparticle-loaded oregano oil nanoemulsion as a potential alternative. Our results demonstrated that the prepared nanoemulsion exhibited enhanced antimicrobial activity, as indicated by larger zones of inhibition compared to the standard ketoconazole and oregano oil combination, as confirmed by the disc diffusion method. This novel formulation holds great promise for the treatment of Mucocutaneous candidiasis, providing an effective and potentially safer alternative to current therapies.
Antioxidant and hypercholesterolemia effects of Lagerstroemia speciosa ethanolic green and red leaf extracts against Lauric acid and ketogenic diets in female albino rats
Authors: Ganesan. G  , Sujatha. P.S.
Published: September 2023

The study investigates the therapeutic value of Lagerstroemia speciosa ethanolic green and red leaf extracts against Lauric acid (LA) and a Ketogenic diet (KGD) in Albino rats. Lauric acid is an important constituent in breast milk, forming nutritional factors and having various medicinal values. It is present in 6.2% of human breast milk, 3.1% of goat milk, and 2.9% in cow milk. It is also found in plant sources like coconut, cohune, and palm kernel oil. The Ketogenic diet uses fat, protein, and low carbohydrate for energy. The experimental groups were fed a Ketogenic diet for 21 days, with the treated groups showing a significant increase in blood cell count and Hg levels. The phytochemical profile reveals abundant phytoconstituents, including corosolic acid, lagerstroemin, and anthocyanin, at high levels. The study compared experimental groups fed with LELE Low Dose and High Dose (250 and 500 mg/kg body weight) and standard groups treated with KGD and Lauric acid. The treated groups showed significant elevations in biochemical parameters and increased blood cells and Hg levels. LELE's anti-hypercholesterolemia activity in KGD significantly reduced body weight, total lipid profile, and blood glucose in a dose-dependent manner. The study found that LELE is safe and non-toxic, with the treated group demonstrating dose dependence and decreased obesity.
Pengujian Daya Balik pada Sinkronisasi Generator dengan Sumber Daya Sangat Besar (Infinite Bus) secara Otomatis Menggunakan Multifunction Relay Tipe GCP-30 di Laboratorium Sistem Proteksi dan Distribusi Jurusan Teknik Elektro
Authors: Yaman Yaman , Hasanuddin Teuku , Yassir Yassir , Fahlevi Reza Tri
Published: September 2023

Daya balik atau motoring adalah peristiwa berubahnya fungsi generator listrik menjadi motor listrik pada saat sinkronisasi generator. Perubahan ini diakibatkan oleh berbaliknya arah aliran daya. Pengamanan generator dari gangguan daya balik biasanya menggunakan reverse power relay, dengan proses sinkronisasi dilakukan secara manual menggunakan synchronoscope. Multifunction Relay tipe GCP-30 adalah alat yang dapat melakukan kedua hal tersebut secara bersamaan. Alat ini berfungsi untuk menyinkronisasi generator secara manual atau otomatis, yang dilengkapi dengan pengaman, termasuk gangguan dari daya balik. Pengujian dilakukan untuk mengetahui pengaruh daya balik terhadap perubahan parameter torsi, arus medan eksitasi generator, dan jumlah beban yang dilayani. Hasil dari pengujian torsi diperoleh bahwa perubahan torsi akan mengubah pembagian beban, yang akan mengakibatkan timbulnya daya balik yang berlebih. Multifunction Relay tipe GCP-30 akan trip pada saat daya balik bernilai -67 W jika di set -8%. Hasil dari pengujian perubahan arus medan eksitasi generator adalah tidak adanya daya balik, tetapi generator akan berubah menjadi beban reaktif. Daya reaktif bernilai -441 VAR pada saat arus eksitasi bernilai 0 A. Adapun hasil dari pengujian perubahan beban adalah bertambah atau berkurangnya daya akan ditanggung oleh sumber daya yang lebih besar, yaitu daya dari sistem.
Pengering Asam Gelugur (Garcinia Atroviridis) Menggunakan ATMega 328 Berbasis Internet of Things (IoT)
Authors: Salahuddin Salahuddin , Akhyar Akhyar , Siregar Tio Nanda Alfikri
Published: September 2023

Keanekaragaman hayati di Indonesia sangat beragam dan memiliki potensi yang tinggi salah satunya adalah rempah-rempah. Rempah-rempah sudah banyak dimanfaatkan dalam bidang industri maupun kesehatan. Namun, terdapat jenis rempah-rempah yang masih belum banyak digali potensinya, salah satunya asam gelugur. Mikrokontroler ATMega328 digunakan sebagai alat pengolah data yang diberikan oleh sensor suhu DS18B20, kemudian kita merancang kontrol suhu untuk melihat suhu yang diinginkan, serta merancang perangkat mekanik dan elektronik alat pengering asam gelugur. Alat yang akan dirancang ini merupakan alat pengering Asam gelugur untuk dijadikan campuran makanan atau rempah-rempah. Pada alat ini suhu untuk mengeringkan asam gelugur dapat diatur sesuai yang dinginkan, setiap suhu yang diatur maka mendapatkan hasil yang berbeda. Proses pengeringan ini dilakukan selama berjam-jam penuh, agar mendapatkan hasil yang optimal. Pada hasil penelitian menunjukan hasil asam yang berat semula 1/2 kg sudah dikeringkan dan diambil contoh dalam waktu 5 jam dengan suhu 60̊c yang sudah di program, dan pada saat kering berat asam tersebut berkurang menjadi 150g atau sama dengan 1 ½ ons, maka dari itu jika di persentasekan mendapatkan hasil 30%. Kesimpulan penelitian ini bahwa semakin lama pengeringan semakin berkurang berat asam yang semula basah. Dari hasil yang di dapat pada pengujian tabel, maka semakin lama waktu pengeringan semakin berkurangnya berat asam tersebut.
Analisis Quality of Service (QoS) Radio Streaming menggunakan Icecast pada Wi-Fi 802.11n
Authors: Rachmawati Rachmawati , Munawar Munawar , Tari Sandian
Published: September 2023

Penelitian ini bertujuan untuk menguji kinerja jaringan dari sistem layanan radio streaming dengan beberapa parameter pengujian, yakni throughput, packet loss, serta delay. Alat ukur performansi yang digunakan pada penelitian ini adalah software wireshark. Pengujian ini dilakukan dengan menggunakan Wi-Fi 802.11n 72 Mbps pada koridor Laboratorium Teknik Elektro Politeknik Negeri Lhokseumawe dengan memperhitungkan format audio dan encoder bit rate yang digunakan audio tersebut. Hasil pengujian performansi di pagi dan siang hari menghasilkan nilai throughput format ogg lebih tinggi dibandingkan dengan format mp3, yakni pada bit rate 320 kbps sebesar 303.428 bps dan bit rate 48 kbps sebesar 435.428 bps. Dari pengamatan semakin besar pengaturan encoder-nya maka semakin besar throughput yang diperoleh. Pengujian di pagi dan siang hari menghasilkan nilai packet loss format ogg lebih tinggi dibandingkan format mp3, yakni pada bit rate 320 kbps sebesar 10,52% dan 10,6%. Pengujian di pagi dan siang hari menghasilkan nilai delay format mp3 lebih tinggi dibandingkan dengan format ogg, yakni pada bit rate 48 kbps sebesar 85,1 ms dan bit rate 320 kbps sebesar 105,72 ms. Berdasarkan standarisasi ITU-T dengan beberapa pengujian yang telah dilakukan client masih dapat mengakses layanan radio streaming dengan kualitas yang baik menggunakan Wi-Fi 802.11n 72 Mbps.
Analisis Konstanta Dielektrik menggunakan Sensor Kapasitif untuk Pemurnian Biodiesel
Authors: Rahmawati Rahmawati , Mardiyanto Arief , Amra Siti , Hanafi Hanafi , Gunawan Gunawan , Al Mawardi Al Mawardi
Published: September 2023

Biodiesel pengganti solar diproduksi melalui reaksi transesterifikasi atau alkoholisis antara trigliserida (minyak nabati) dengan metanol (reaktan) untuk menghasilkan fatty acid methyl ester (FAME) yang dikenal dengan nama biodiesel dan gliserol. Biodisel dan gliserol dipisahkan menghasilkan biodiesel yang disebut dengan biodiesel kotor. Pemurnian biodiesel untuk menghilangkan pengotor yang tidak diinginkan sangat penting dan merupakan teknologi kritis yang sangat dibutuhkan. Proses pemurnian dilakukan dengan proses pencucian dan evaporasi. Proses pencucian biodiesel bertujuan untuk menghilangkan sisa kotoran yang tertinggal atau pengotor lainnya yang tidak ikut bereaksi selama reaksi transesterifikasi. Permasalahan yang diteliti adalah bagaimana sensor dielektrik dapat digunakan untuk monitoring proses pencucian biodiesel secara real time. Untuk itu terlebih dahulu dilakukan pengukuran konstanta dielektrik menggunakan sensor dielektrik berupa sensor kapasitif. Biodiesel hasil transesterifikasi masih mengandung pengotor antara lain sisa air, gliserol dan metanol. Sifat dielektrik memiliki korelasi kuat dengan sifat umum dan kimia biodiesel. Untuk mengukur kualitas selama proses pemurnian dapat menggunakan sensor dielektrik, karena sifat dielektrik memiliki korelasi terhadap sifat fisik dan kimia biodiesel. Pelaksanaan penelitian meliputi pengukuran konstanta dielektrik masing-masing komponen biodiesel, air, gliserol dan methanol serta biodiesel pada berbagai persentase kandungan air. Tujuan utama penelitian adalah menghasilkan pengukuran konstanta dielektrik biodiesel dan sisa pengotor pada proses pencucian biodiesel. Metode yang digunakan dalam penelitian ini adalah metode eksperimental dengan menyajikan hasil pengamatan konstanta dielektrik dalam bentuk tabel dan grafik kemudian dibahas secara deskriptif. Pengukuran konstanta dielektrik biodiesel, air, gliserol dan methanol menggunakan LCR meter. Hasil pengukuran konstanta dielektrik biodiesel, metanol, gliserol dan air adalah 4.53, 32.02, 42.28 dan 77.03 berturut-turut pada frekuensi pengukuran 100 kHz. Konstanta dielektrik biodiesel meningkat dengan meningkatnya kandungan pengotor pada biodiesel. Ditentukan persamaan regresi linier di mana variabel x sebagai kandungan pengotor dan variabel y sebagai nilai dielektrik. Nilai dielektrik biodiesel untuk kandungan pengotor adalah y=0,01x2+0,021x+4,1 (metanol), y=-002x2+0,3x+4,3 (gliserol), y=0,005x2+0,05x+4,5 (air). Konstanta dielektrik biodiesel meningkat dengan meningkatnya kandungan pengotor dalam biodiesel.
Free Vibrational Behavior of Bi-Directional Functionally Graded Composite Panel with and Without Porosities Using 3D Finite Element Approximations
Authors:   Vellore Institute of Technology, Ghatage Pankaj S. , Sudhagar P. Edwin ,   Affiliated to Shivaji University
Published: September 2023

The frequency characteristics of bi-directional functionally graded(FG)rectangular panels with and without porosities are examinedin this workusing 3D finite element approximations.Theproperties ofgraded panel consist metal and ceramic materialvaried smoothly inbi-direction. The material properties of this highly heterogeneous material are obtained using the Voigt material model and Power-law. The present model is developed using a customized computer code anddiscretized using three-dimensional solid 20-noded quadrilateral elements. The mesh refinement isconductedto presentthe convergence test.The validation test is presented by showing comparison ofthe obtained findingswith the results reportedin thepreviousliterature. At a later stage, comprehensive parametric research is presentedthrough numerical illustrations which reveal that the geometrical and material parameters of bi-directional functionally graded panel affect its frequency characteristics,significantly. Finally, the developed 3D FEM model to predict the free vibrational characteristicsof multidirectional FG rectangular plateswith and without porosities will be the reference for the continuation of research in this area.
Optimization of CMT Welding Parameters of Stellite-6 on AISI316L Alloy Using TOPSIS Method
Authors:   Research Scholar –Bharath Institute of Higher Education and Research, Thiagarajan Thinesh Babu , D Raguraman ,   Research Supervisor –Bharath Institute of Higher Education and Research, Ponnusamy Sengottuvel ,   Research Supervisor –Bharath Institute of Higher Education and Research
Published: September 2023

Thisarticle discusses the welding parameters optimization to find the quality of stellite-6 cladding on AISI304L austenite alloy using a new optimization method called Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). The experiments(31 nos.) were carried out with the cold metal arc transfer welding method (CMT) based on the central composite design (CCD). The cladding material is the stellite-6 alloy which is appreciated for its corrosion and wear resistance. Four factors (welding current, voltage, welding speed and torch angle) and five levels were considered for the experiment and the optimization. It is necessary to find the optimized parameters for the industrial applications as a huge number of experiments are not recommended. The optimization results showed that the 2nd experiment had the 1st rank with high relative closeness and the 19th experiment was in the last rank. Higher current and low welding speed yielded good results and a low corrosion rate of 0.004582 mm/yr. Furthermore, the Micro-structural, Corrosion study and the SEM-EDS of the specimen produced by the 2nd experiment are discussed here. Cr and Co elements were most abundant, according to an EDS study, in the cladding region.
Flow Cytometric Analysis of Lymphocyte Subsets of Covid-19 Patients from A Single Centre in Turkey
Authors: ELVERDİ Tuğrul , ERÇALIŞKAN Abdülkadir , KARAALİ Rıdvan , BALKAN İlker İnanç , ÖZMEN Deniz , SALİHOĞLU Ayşe , METE Birgül , EŞKAZAN Ahmet Emre , BAŞLAR Zafer , TABAK Fehmi , AR Cem
Published: September 2023

Background:

Lymphocyte counts have been shown to negatively correlate with the severity and different outcomes in Covid-19. The aim of this single centre study is to analyse the distribution of lymphocyte subsets in response to SARS-CoV-2 infection and its relation to the severity, course and prognosis of the disease.

Methods:

Blood samples were obtained from 67 consecutive patients between April 2020 and July 2020. Data on other laboratory parameters, and clinical course were collected retrospectively from patient files and patints were defined to have as severe or non-severe (mild/moderate) disease. Leukocyte subsets to be studied were identified by using flow cytometric analysis. Patients were allocated into 3 groups based on the day of blood sample collection for the flow cytometric analysis: Days 0-7, Days 8-14 and Days >14 as Group I, Group II and Group III, respectively. In 10 available of 67 patients an additional flow cytometric analysis was done 7-10 days after the initial sampling.

Results:

Lower total lymphocyte, CD3 positive, CD4 positive and B-cell counts were identified in severe infection compared to non-severe infection group which were also correlated with high serum CRP, D-dimer and ferritin levels. NK and monocyte counts were not different between the two groups. Activation markers CD38 and HLA-DR on CD4 and CD8 positive lymphocytes also were not different in either group.

Conclusion:

CD3 and CD4 lymphopenia were lower in accordance with previous studies and were associated with severe disease. The expectancy of high activation markers was not met. Future studies with detailed subgroup analyses at different time-points, and immune profiling after vaccination as well as during new infection in vaccinated patients will shed more light on our general knowledge of the immune response to COVID-19 and viruses in general.
Children-Dietary Inflammatory Index and Adherence to the Mediterranean Diet in Children with Overweight and Obesity: Are They Associated with Cardiometabolic Risk Parameters?
Authors: YURTDAŞ DEPBOYLU Gamze , GÜLMEZ Ceren , KANIK Muhammet Ali
Published: September 2023

Purpose: This study was planned to assess the relationship between the children’s dietary inflammatory index (cDII), adherence to the Mediterranean diet (AMD), and metabolic control parameters in children with overweight and obesity.

Methods: This cross-sectional was conducted in children with overweight and obesity aged 7-18 years. Sociodemographic, biochemical, dietary, and lifestyle data were collected using a questionnaire. Mediterranean Diet Quality Index (KIDMED) was used to evaluate AMD. Body weight, height, neck, waist, and hip circumference were measured. Dietary intake and cDII were assessed with a three-day food consumption record.

Results: The mean cDII score was 2.2∓0.94 (range from -0.43 to 4.39). Of the total participants, 12% had high and 38.7% had low AMD. There were no significant differences between cDII and biochemical and anthropometric parameters. The proportion of participants with high insulin levels (53.4%) was higher in participants with low AMD group than in those with high AMD (32.6%) (p=0.011). The proportion of participants with insulin resistance was higher in the low AMD group than in the medium/high adherence group (53.4% vs. 37.0%, p=0.047). There was no significant relationship between AMD and lipid profile. Logistic regression analysis showed that participants with low AMD had high insulin levels to be 2.055 times (95% CI= 1.009-4.186. OR=2.055) compared to participants with moderate/high AMD (p=0.047). cDII scores and AMD were not associated with insulin resistance.

Conclusion: This study showed that low AMD was associated with high insulin levels, but cDII was not associated with cardiometabolic risk factors in children with overweight and obesity.
Validity and Reliability of the Perinatal Grief Intensity Scale in a Chinese Clinical Sample: A Prospective Cross-Sectional Study
Authors: Xu Jianping , Gu Shuiqin , Su Shuihong
Published: September 2023

Background: This study introduced the Perinatal Grief Intensity Scale (PGIS) and applied it to assess the reliability and validity of perinatal loss in Chinese mothers. Methods: To sinicize PGIS and cultural debugging of the scale, reliability validity was assessed in this prospective cross-sectional study. Results: The Chinese version of the PGIS contained 14 items in three dimensions: reality, confront others, and congruence. The content validity index (CVI) at the total scale level, mean scale level, and item level was 0.92, 0.909, and 0.860–1.000. Exploratory factors were identified as three metric factors with a cumulative variance contribution rate of 66.627%. The Chinese version of the Perinatal Grief Scale (PGS) was used as a calibration standard, and the correlation coefficient was 0.759. The total Cronbach’s alpha coefficient for the Chinese version of the PGIS was 0.768, with a fold-half reliability of 0.749. The scale showed good reliability and validity. Conclusions: The Chinese version of the PGIS was used as a calibration standard by exploratory factor testing, and the correlation coefficient was good, and the scale had good reliability and validity for application in China.
The Impact of Advanced Maternal Age on Neonatal Outcome in Preterm Births before 34 Weeks
Authors: Tairy Daniel , Gluck Ohad , Izaik Yakira , Bar Jacob , Weiner Eran , Barda Giulia
Published: September 2023

Background: In recent years a trend towards childbearing at older maternal age is evident. Most of the current literature investigated the association between advanced maternal age and neonatal outcome at term. We aimed to study the outcomes of the mother and the neonate among preterm births of women of advanced maternal age. Methods: This retrospective study between 2009 to 2017, comprised 494 singleton preterm births between 24 and 34 weeks gestation, of which 116 (23%) were of 35 years old or older (advanced maternal age) and 378 (77%) were of younger women. The medical records were reviewed and the outcomes of the mother and the neonate were compared between advanced maternal age (≥35 years) and younger women. Results: The rate of severe intra-ventricular hemorrhage (IVH) and of composite adverse neonatal outcome was lower among advanced maternal age women compared to younger women (p = 0.02 and p = 0.05 respectively). In multivariate regression analysis, composite adverse neonatal outcome was found to be independently inversely associated only with advanced maternal age (adjusted odds ratio (aOR) 0.45 95% confidence interval (CI) 0.23–0.86). Conclusions: Advanced maternal age was not found to be a risk factor for adverse neonatal outcome among preterm births before 34 weeks, and might be a protective factor from early neonatal complications.
Increasing O-GlcNAcylation Attenuates tau Hyperphosphorylation and Behavioral Impairment in rTg4510 Tauopathy Mice
Authors: Rostgaard Nina , Jul Pia Holm , Garmer Mats , Volbracht Christiane
Published: September 2023

Background: Tauopathies such as Alzheimer’s disease (AD) are characterized by abnormal hyperphosphorylation of the microtubule-associated protein tau (MAPT) aggregating into neurofibrillary tangles (NFTs). O-linked β-N-acetylglucosamine (O-GlcNAc) modifications have been suggested to regulate tau phosphorylation and aggregation and N-acetylglucosaminidase (OGA) removes GlcNAc moieties from proteins. Methods: We investigated effects of the OGA inhibitor Thiamet G in rTg4510 primary neuronal cultures and in rTg4510 mice. The rTg4510 mice overexpress human tau harboring the P301L mutation and display an age-dependent progression of tau pathology including hyperphosphorylated tau species and NFTs. Aged rTg4510 mice exhibit a non-mnemonic behavioral defect involving a hyperactive phenotype that is associated with the progression of tau pathology. Results: Thiamet G increased overall O-GlcNAc levels and crossed the blood brain barrier in rTg4510 mice. The free fraction of Thiamet G in the brain was 22-fold above the half maximal effective concentration (EC50) measured in rTg4510 primary neurons. Chronic Thiamet G treatment (18 weeks) initiated in young 6 week old rTg4510 mice increased brain O-GlcNAc levels and this corresponded with a significant reduction in soluble and insoluble hyperphosphorylated tau in aged 24 week old rTg4510 mice. Levels of normally phosphorylated P301L tau were not altered under these conditions. Reduction of hyperphosphorylated tau species by increased O-GlcNAcylation was associated with significant attenuation of hyperactivity in 24 week old rTg4510 mice. Conclusions: Our findings support the pharmacological inhibition of OGA as a potential therapeutic approach for the treatment of AD and other tauopathies.
Research on the methods of teaching Japanese at the university: historical aspects
Authors: Xia Jianxue
Published: September 2023

Japanese is one of the most popular languages and one of the most popular foreign languages in China. Despite the fact that many students have a fairly high level of Japanese language proficiency at the time of admission to the university, effective methods of teaching Japanese in Chinese universities are still an open question. This article discusses the methods of teaching Japanese in Chinese universities and identifies the most effective.
Tugas 1
Authors: Pulungan Amru
Published: September 2023

sektor pertanian, kehutanan, dan perikanan mempunyai kontribusi yang paling besar terhadap perekonomian di Kabupaten Pasaman Barat. Hasil analisis Tipologi Klassen menunjukkan bahwa sektor pertanian, kehutanan, dan perikanan, dan sektor industri pengolahan perlu diperbaiki kinerjanya agar mampu mendorong pertumbuhan ekonomi di Kabupaten Pasaman Barat. Kedua sektor tersebut juga merupakan komoditas basis, dengan nilai rata-rata LQ sektor pertanian sebesar 1,83, dan nilai rata-rata sektor industri pengolahan sebesar 1,58.
FOXK2 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that forkhead box K2, encoded by FOXK2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. FOXK2 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of FOXK2 in primary tumors was correlated with patient overall, distant metastasis-free and recurrence-free survival. Modulation of FOXK2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Persepsi orang tua terhadap pendidikan seks pada anak usia dini
Authors: Gulo Rita Dewisman
Published: September 2023

Penelitian ini bertujuan untuk memperoleh data empiris mengenai persepsi orang tua terhadap pendidikan seks pada anak usia dini di Dwikora Medan Helvetia. Sampel penelitian ini adalah 50 orang tua yang mempunyai anak usia dini dan menyekolahkan anaknya di Kecamatan Dwikora Medan Helvetia. Teknik pengambilan sampel pada penelitian ini menggunakan teknik cluster random. Metode yang digunakan dalam penelitian ini adalah penelitian kuantitatif dengan menggunakan teknik survei. Teknik analisis data yang digunakan adalah statistik deskriptif. Hasil penelitian ini secara keseluruhan menunjukkan bahwa persepsi orang tua terhadap pendidikan seks pada anak usia dini di Dwikora Medan Helvetia berada pada kategori “cukup baik”. Berdasarkan perhitungan yang diperoleh dari 50 orang tua menunjukkan bahwa 64% orang tua berada pada kategori cukup baik. Selanjutnya terdapat 26% orang tua yang berada pada kategori baik. Sedangkan orang tua yang berada pada kategori kurang sebanyak 10%.
SPINDOC (C11orf84) is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that spindlin interactor and repressor of chromatin binding, encoded by SPINDOC, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. SPINDOC mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of SPINDOC in primary tumors was correlated with patient recurrence-free survival. Modulation of SPINDOC expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
TMEM223 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that transmembrane protein 223, encoded by TMEM223, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. TMEM223 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of TMEM223 in primary tumors was correlated with patient recurrence-free survival. Modulation of TMEM223 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
MRPS7 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that mitochondrial ribosomal protein S7, encoded by MRPS7, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. MRPS7 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of MRPS7 in primary tumors was correlated with patient recurrence-free survival. Modulation of MRPS7 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Advances in Medical: Transforming Healthcare in the Digital Age
Authors: Hani Zaki
Published: September 2023

Advances in Medical: Transforming Healthcare in the Digital Age
Harnessing Data Virtualization for Informed Decision Making in Big Data
Authors: William Hannah
Published: September 2023

Harnessing Data Virtualization for Informed Decision Making inBig Data
S100A11 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that S100 calcium-binding protein A11, encoded by S100A11, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. S100A11 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of S100A11 in primary tumors was correlated with patient overall, distant metastasis-free and recurrence-free survival. Modulation of S100A11 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
FKBPL is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that FK506-binding protein-like, encoded by FKBPL, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. FKBPL mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of FKBPL in primary tumors was correlated with patient recurrence-free survival. Modulation of FKBPL expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.