bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Daily Traffic Activities At Four-Legged Intersection Of Cimencrang, Al Jabbar Mosque Area, Using PKJI 2023
Authors: Lazuardi Rahmat , Septiawati Vera , Septiani Anis
Published: December 2024

This study evaluates the impact of daily traffic activity at the four-legged intersection at the Cimencrang railway crossing, in the Al Jabbar Mosque area, using the Indonesian Road Capacity Guidelines (PKJI) 2023. The aim of this study is to assess the traffic performance affecting the efficiency of at-grade road and railway crossings in the area. This evaluation is essential to understand the traffic dynamics in the area, which will help the government in designing traffic and transportation management methods to reduce future congestion. Traffic data was collected through direct surveys during peak hours on weekdays, covering vehicle volume, vehicle types, and the geometric dimensions of the roads at the intersection. The evaluation results indicate that the intersection’s Volume to Capacity Ratio (VCR) at the study site is 0.74. The findings also suggest that this four-legged intersection frequently experiences critical conditions, with Levels of Service (LOS) ranging from C to E during busy hours. The study recommends improving traffic management and infrastructure to enhance performance and traffic conditions, as well as road user safety in this area. It is hoped that these findings can serve as a foundation for local government in planning more effective traffic policies in the area, and provide insights into the processes and procedures of traffic evaluation at four-legged intersections.
The Police Power of the National Health Surveillance Agency – ANVISA
Authors: Dimas Augusto da Silva , Rafaela Marinho da Silva
Published: December 2024

The National Health Surveillance Agency (ANVISA) is a public institution created by Law 9782/1999, which integrates the field of Collective Health and acts in the prevention, control, and inspection of sanitary conditions in various sectors, such as food, health, pharmacies, hospitals, and commercial establishments. Its main objective is to guarantee the protection of public health, ensuring that products, services, and environments comply with established standards, to promote health and preventing diseases. To exercise its inspection and control function, Sanitary Surveillance has the power of sanitary police, which gives it the authority to apply necessary measures and curb practices that pose risks to the health of the population.
The performance of the Sanitary Surveillance is fundamental to prevent health risks in any part of society and to guarantee national programs for patient safety. It is also essential to prevent diseases, control risks, and monitor compliance with health standards and specific regulations. The police power of Sanitary Surveillance consists of establishing norms and technical regulations, carrying out inspections and inspections, issuing temporary or permanent interdiction orders in establishments that do not comply with the norms, as well as forwarding complaints to the Public Ministry in cases of crimes against public health. Arrests carried out by Sanitary Surveillance agents are extreme measures and applied in serious situations of risk to public health or when there is repeated disrespect for sanitary regulations. The prohibited establishments have the right of defense and may seek to regularize the situation to obtain the release of activities.
The performance of the Sanitary Surveillance has significant impacts on the prevention of disease outbreaks and epidemics. Identifying and correcting inappropriate practices helps to prevent the spread of pathogenic agents and reduce the risk of contagion in collective environments. The institution’s preventive and supervisory activities contribute to reducing risks to the population’s health, preventing disease outbreaks, food poisoning, and the proliferation of pests, among other problems. Finally, the importance of exercising police power with transparency, impartiality, and respect for individual rights is emphasized, always aiming at the collective interest and the promotion of the common good. In summary, Health Surveillance plays an essential role in protecting public health, seeking to ensure that the population has access to safe products and services, contributing to the improvement of quality of life and disease prevention.
Pretreatment of sugarcane bagasse autoclave via assisted-alkali hydrogen peroxide and enzymatic hydrolysis on mucor circinelloides cultivation
Authors: Soegiantoro Gregory Hope , Alhikami Akhmad Faruq , Pramata Azzah Dyah , Hibatullah Daffa , Refansah Fani Ahmad , Wijaya Fernando , Rafidianto Satria Rafif , Maulida Mutiara Rizki , Nugroho Gunawan , Hamidah Nur Laila
Published: December 2024

This study aims to evaluate the characteristics and feasibility of the autoclave assisted-alkali hydrogen peroxide delignification and enzymatic hydrolysis pretreated sugarcane bagasse for Mucor circinelloides cultivation to produce biofuels. The experimental setup consists of unpretreated sugarcane bagasse (SCB), delignified SCB, hydrolyzed SCB, and delignified-hydrolyzed SCB. The characterization was done using FTIR, XRD, and HHV calorimeter. The pretreatment of sugarcane bagasse using autoclave-assisted alkali hydrogen peroxide delignification was able to remove the lignin and hemicellulose. At the same time, the following enzymatic hydrolysis was able to increase the digestibility of sugarcane bagasse’s cellulose, making it suitable for Mucor circinelloides cultivation. The cultivation of Mucor circinelloides was done in the 100 ml sugarcane bagasse hydrolysate medium for 72 hours and a 250 rpm stirring rate produced approximately 9.1 grams of lipid.
A Comparative Study of Spatial Narratives in Eastern and Western Cyberpunk Films
Authors: Long Siyu , Choi Won-Ho
Published: December 2024

This study takes representative cyberpunk films from the East and the West as the research object, compares them from the perspective of spatial narration, and reveals the similarities and differences in their narrative styles and cultural expressions. In terms of physical space, narrative space, psychological space, auditory space, and virtual space, it explores the complex relationship between technology and humanity, society and individual, and its multidimensional expression in cyberpunk films from the East and the West. This study emphasizes the central role of spatial narratives in Eastern and Western Cyberpunk Films and provides theoretical support for an in-depth study of the global influence of cyberpunk culture and its narrative strategies.
The Relationship Between Academic Self-Discipline Perceptions and Quiet Quitting Levels of Undergraduate Students
Authors: Erol İsmail , Çayak Semih , Karsantık İsmail
Published: December 2024

The objective of this study is to investigate the relationship between undergraduate students' perceptions of academic self-discipline and their levels of quiet quitting. The study was conducted with 312 students pursuing their studies at higher education in-stitutions in the Tekirdağ and Istanbul provinces. The Academic Self-Discipline Scale, developed by Şal (2022) and adapted into Turkish by Erduran Tekin & Şal (2023), and the quiet quitting Scale, developed by Savaş and Turan (2023), were employed as data collection instruments in the research, which was designed in accordance with the relational survey model. The findings of the study indicated that undergraduate stu-dents exhibited high levels of academic self-discipline, while their levels of quiet quit-ting were at a medium level. Furthermore, the study revealed a negative yet moderate and significant association between academic self-discipline and quiet quitting levels among undergraduate students. The regression analysis demonstrated that undergradu-ate students' academic self-discipline perceptions were a notable predictor of their quiet quitting levels, thereby distinguishing the study from existing literature. In alignment with the findings of the research, recommendations were put forth with the aim of reducing the prevalence of silent resignation among undergraduate students and enhancing their academic self-discipline.
Eski Türkçede Eşdizim, Konsept, İstem ve Kültür Dil Bilimi İlişkileri Üzerine
Authors: Besli Ertan
Published: December 2024

Araştırma konumuz; eski Türkçe metinlerde "törü" kavramı üzerinden eşdizim, konsept ve istem arasındaki ilişkilerin kültür dil bilimi perspektifinden incelemesini ve ortaya konmasını içermektedir. Çalışmada, eşdizim, konsept, istem kavramları ve aralarındaki ilişkiler üzerinde durulmuştur. Eski Türkçe özelinde eşdizim, konsept ve istem kavramlarının kültürel yansımaları, söz konusu kavramlar arasındaki yapı, söz dizimi ve anlam ilişkilerinin gerçekleşme şekilleri ortaya konmaya çalışılmıştır. Çalışmamızın teori bölümünde, söz konusu kavramlarla ilgili teori bilgisi ve alan yazındaki tanımlar verilmiştir. Araştırmanın uygulama kısmında, Eski Türkçe metinlerden seçilen örnek cümlelerin araştırma konumuz bağlamında analizlerine yer verilmiştir. Eski Türkçe özelinde eşdizim, konsept ve istem kavramlarının kültürel yansımalarını ortaya koymak, söz konusu kavramlar arasındaki yapı, söz dizimi ve anlam ilişkilerinin gerçekleşme şekillerinin analizini yapmak ve çıkan sonuçları genelleyerek yorumlarını yapmak çalışmamızın amacını ve beklenen sonucunu meydana getirmektedir. Araştırmanın örneklemi için sahanın önemli eserlerinin yer aldığı metin veri tabanından “töre” kavramı için eşdizim ve konseptler tespit edilecektir. Ulaşılan bulgular değerlendirme bölümünde, Türkoloji, dil bilimi ve kültür dil bilimi aracılığıyla analiz edilip yorumlanmıştır.
Analysis of the metabolite profile of mistletoe leaves (Dendrophthoe pentandra (L.) Miq.) as an Epiphyte on Lime Using the GC-MS Method
Authors: Juswardi  , Karissa Clara  , Harmida  , Nina Tanzerina  , Nita Aminasih  , Mustafa Kamal
Published: December 2024

Dendrophthoe pentandra (L.) Miq., a mistletoe species from the Loranthaceae family, can thrive as an epiphyte on various host plants, including lime trees. This mistletoe has potential as a herbal plant due to its bioactive properties, stemming from a diverse range of metabolites. Therefore, this analysis aims to identify different compounds and explore groups of compounds that may exhibit potential bioactivity in ethanolic extracts of D. pentandra leaves on lime, utilizing the GC-MS method. The analysis revealed a total of 68 detected metabolite compounds, comprising 51 main compounds that represent 90.49% of the total abundance. Notably, 16 dominant compounds were identified, including Melezitose (6.64%), 3-Methylmannoside (6.38%), ß-D-Mannofuranoside, methylated (4.76%), 3-O-Methyl-D-glucose (3.70%), Myo-Inositol, 4-C-methyl (31.29%), and Tetradecanoic acid, ethyl ester (3.81%). In terms of abundance based on compound class, carbohydrates account for 65%, fatty acids for 15%, and phenols for 10%, with the remaining compounds comprising other classes. The unique compounds found in mistletoe leaves on lime exhibit various bioactivities, such as antioxidant, anticancer, antibiotic, antiseptic, antihyperglycemic, antihistamine, antiandrogenic, antiarrhythmic, antiasthmatic, and diuretic properties. Further research is necessary to explore the bioactive compounds in mistletoe D. pentandra across various potential host plants and to conduct additional metabolomic analyses.
AI-Powered Conversational Interfaces for CRM/ERP Systems
Authors: Sai Kiran Reddy Malikireddy  , Snigdha Tadanki
Published: December 2024

This study examines the integration of conversational AI agents into CRM/ERP platforms, focusing on UI/UX design and NLP capabilities. It highlights the development of user-friendly chatbots for automating workflows, addressing multilingual user interactions, and leveraging backend machine learning pipelines for context-aware responses.
A review on effect of different herbicides on growth, reproduction and biochemical markers of earthworm
Authors: Seema Dixit  , Swati Bardiya
Published: December 2024

Herbicides, widely used in modern agriculture, play a pivotal role in controlling weeds and enhancing crop productivity. However, their effects on non-target soil organisms, such as earthworms, are a growing concern due to the ecological importance of these organisms in soil fertility and structure. This review examines the impact of various herbicides on earthworm growth, reproduction, and biochemical markers. Studies reveal that herbicide exposure can adversely affect growth rates, cocoon production, and hatchling success in different earthworm species. Furthermore, biochemical markers such as oxidative stress enzymes, metabolic activity, and biomarkers of neurotoxicity provide insights into sub-lethal effects and underlying physiological mechanisms. The variation in sensitivity among species is influenced by herbicide type, concentration, and exposure duration. Understanding these impacts is essential for developing sustainable agricultural practices that minimize harm to soil biodiversity. This review highlights the need for eco-toxicological evaluations to guide safe herbicide use.
Environmental determinants of infectious disease incidence: A discrete time series analysis in Bangladesh
Authors: Khondoker Rukyath Alam  , Mohammad Ahsan Uddin
Published: December 2024

Weather is an important determinant for human health. There is an apparent increase in outbreak of many infectious diseases which reflects the combined impacts of rapid demographic, environmental, social, technological and other changes in our way-of-living. This study aimed to analyze the effects of environmental factors on infectious disease occurrences in Bangladesh using time series data from 2013 to 2022. Environmental data (monthly average temperature, monthly average relative humidity and monthly average rainfall) were collected from the Bangladesh Agricultural Research Council (BARC) and disease data (Tetanus, HIV and Chickenpox counts) were obtained from the Infectious Disease Hospital in Dhaka. Utilizing Poisson and Negative Binomial (NB) Generalized Linear Models (GLMs), the impact of weather variability on disease transmission was examined. The best-fitted models yielded AIC values of 682.7 for Tetanus, 605.96 for HIV and 608.01 for Chickenpox, with corresponding RMSE values of 3.33, 0.22 and 1.67. The study found that monthly average rainfall negatively affects Tetanus counts while temperature and humidity had significant positive and negative effects on Chickenpox counts respectively. No significant effect of environmental factors on HIV counts was observed. These findings can inform preventative measures and strategies to reduce disease impact.
The relationship between dental caries and vision impairment based on the DMFT Index: A literature review
Authors: Zahrah Salsabila Putri Bangun  , Aura Zalfa Ghassani Syahdiar
Published: December 2024

Objectives: This study aims to explore the relationship between dental caries and vision impairment, specifically in individuals assessed using the Decayed, Missing, and Filled Teeth (DMFT) index. The research focuses on identifying the prevalence of dental caries, factors influencing oral health, and the challenges faced by visually impaired individuals in maintaining good oral hygiene.
Methods: A literature review method was employed to gather data from international scientific journal articles accessed through databases such as Google Scholar, PubMed, and ScienceDirect. Keywords used for the search included "Dental Caries", "Vision Impairment", and "DMFT". Only articles published in the last ten years (2015-2024) were considered. The selected studies were analyzed to draw conclusions regarding the oral health status of visually impaired individuals.
Results: The review found a consistently high prevalence of dental caries among individuals with visual impairments, with mean DMFT scores ranging from 1.23 to 2.71. Contributing factors include difficulties in maintaining oral hygiene, limited access to dental care, lack of awareness about proper brushing techniques, and dietary habits such as frequent snacking. Gender differences were noted, with female participants generally showing poorer oral health outcomes.
Conclusion: The study highlights the significant oral health challenges faced by visually impaired individuals, including a high prevalence of dental caries. Interventions focusing on education for both caregivers and patients, improved access to dental care, and preventive measures such as fluoride toothpaste use are crucial. This study emphasizes the importance of addressing these challenges to improve the quality of life and health outcomes for visually impaired individuals.
The interpretation of the Form of Corruption and the concept of the Code of Corruption Forms
Authors: Dimitris Prontzas
Published: December 2024

This article examines a very significant issue: the meaning of a form of the phenomenon of corruption and the prerequisites that must exist for a scholar, to attribute the term "form of corruption" to a specific act. The article, also explores the concept of the “Fundamental Equation of a Form of Corruption”, analyzes the notions of impact and the identity of a form’s impact and investigates how these differ across countries worldwide. The article concludes by presenting the forms of the corruption phenomenon, which the author has termed the “Code of Corruption Form”.
Kewenangan Desa Dalam Pengelolaan Pariwisata Untuk Mendukung Peningkatan Pendapatan Desa
Authors: Maladi Rossi Filia , Firdausy Adriana Grahani , Madalina Maria
Published: December 2024

Village development is an important aspect in the development of the Indonesian Nation. One sector that can be utilized for village development is tourism. Village has the authority to develop its tourism as a form of managing the potential of the village. Village tourism in the process of its development is inseparable from obstacles such as low human resources, conflicts between villagers in the development of village tourism, etc. This research discusses how the authority of Kemuning Village in tourism management to support the enhancement of Kemuning Village's original income and what obstacles the Kemuning village government experiences in managing the village's tourism potential to support village income. This research is a type of empirical legal research with a descriptive research style and a qualitative approach. The data collection techniques used are field research and literature study. Based on this research, Kemuning Village has already executed some of its authorities in tourism management to support the increase of village income, but there are also some authorities that have not been executed by the Kemuning Village government. The obstacles experienced by the Kemuning Village government in managing tourism potential to support village income are the lack of people who understand and can utilize the potential of the tourism sector, the lack of coordination between the Kemuning Village Government and the Karanganyar Regency Government, the implementation of BUM Desa that is not yet optimal, and the absence of village regulations related to tourism management and levies on tourist business services.
Upaya Pencegahan Tindakan Perundungan Disabilitas di Kota Makassar
Authors: Yanlua Siti Zainab , Yanlua Nurfitri
Published: December 2024

Disabled people are minorities who are vulnerable to bullying because of their different characteristics. The impact of bullying is very detrimental because it can disturb their mental health, therefore preventive measures are needed so that they can be protected. Efforts to prevent acts of disability bullying that are carried out cannot only be carried out by one party, but require cooperation between persons with disabilities, families, schools, the community and the government. The government as the party that provides facilities then the community and families help prevent it by ensuring that no discrimination is experienced.
Pengaruh Maraknya Kasus Perceraian Public Figure Terhadap Pandangan Masyarakat Umum Tentang Pernikahan Dalam Hukum Islam
Authors: Pratama Angga Adi
Published: December 2024

The divorce phenomenon that has occurred among artists in Indonesia recently has often been in the spotlight of netizens. In the virtual world and in the real world, divorce cases are a hot topic in Indonesian society today. The background to this research is the widespread news on social media about the phenomenon of female public figures, influencers or celebrities suing their husbands for divorce in court. There are various problems faced when living a married life, starting from cases of domestic violence, deviant behavior by the husband or wife, to infidelity. The method used by the author in this research uses qualitative research and library research, which emphasizes in-depth observation of a phenomenon which is then studied using scientific logic which refers to reading book literature, research journals, and statutory regulations, both Islamic law and law. positive. The research results explain that the impact of divorce, especially what happens to public figures, can cause various problems and negative impacts on those closest to them and people who receive information about the divorce. Views regarding the definition of marriage have become very complex due to the increasing number of divorce cases that occur.
Penegakan Hukum Korban Bullying Diberbagai Tingkat Sekolah Di Indonesia
Authors: Oktaviani Vivih , Dianah Dianah , Subakhti Hasanudin , Khalimy Akhmad
Published: December 2024

The purpose of this study is to determine (1) the forms of bullying behavior (2) the factors causing the emergence of bullying behavior (3) the impact of bullying behavior (4) Efforts to handle bullying behavior using WDEP technique reality counseling. This study uses an approach with a clinical case study method. The results showed that 1) The forms of bullying carried out by NM were verbal bullying such as calling, calling by nicknames, and calling with parents' names, and physical bullying such as nudging and pinching. The intensity of NM bullying is 5-6 times a day which is done in the classroom and in the school canteen. Characteristics of victims of bullying NM are female 2) The factors that cause NM to do bullying are from parents, NM's personal self, and NM's association with naughty school friends, and supervision from the school on student activities that is still lacking. 3) The impact of bullying behavior by NM causes his learning achievement to decline and is shunned by his friends. 4) The handling effort is done by using WDEP technique counseling. The results of the treatment showed a decrease in bullying behavior. These changes occur because of a change in awareness within the counselee that focuses on current events or current conditions, on personal strengths or what the counselee wants, and encourages individuals to develop better behavior so that it can be useful for the future for the subject and for society. as well as country.
Problematika Hak Eksekutorial Jaminan Fidusia: Perspektif Kepentingan Debitur
Authors: Panjaitan Wijaya Natalia
Published: December 2024

A common problem in the enforcement of fiduciary guarantees is the seizure of collateral that violates consumer rights. Creditors often seize collateral without taking into account consumer rights protected by law. This can lead to disputes between the creditor and the debtor. The purpose of this research is to analyze the problems of fiduciary enforcement rights from the perspective of debtors' interests. The research method used is Normative Juridical Research with the type of library research. Debtors must check the credit agreement more carefully, in particular the clause "voluntary execution of the agreement"; if the clause is absent, the execution cannot be carried out unilaterally without any legal remedy declaring the debtor in default.
Pertanggungjawaban Hukum Terhadap Anak Sebagai Pelaku Tindak Pidana Pencurian
Authors: Febriyandi Hardiki , Surahman Surahman
Published: December 2024

The theft committed by children must have several factors, namely several economic components or factors, parents because they do not pay attention to their children and thus commit acts against the law, social factors, and mass media factors. A child is a person who is not yet competent or a minor. What is called a child is a child who is not yet 18 years old and includes shildren who are still in the womb. This research aims to find out who is legally responsible for violations committed by children of theft according to Indonesian law, the factors that cause theft in cases involving Decision Number 1/Pid.Sus-Anak/2023/Pn Bpp. A normative approach, such as literature research based on laws and cases, is used in this research, these legal resources are classified into primary, secondary and tertiary. The results of this research are that children must be able to take responsibility for their actions which cause unlawful acts and child perpetrators must be imprisoned and trained in Special Children’s Correctional Institutions. Apart from that, social, economic, mass media (which is influenced by electronic media), and parental factors contribute to teenager committing illegal acts of theft. The judge then made a decision in case number 1/Pid.Sus-Anak/2023/PN BPP. It is appropriate to apply Article 363 paragraph (1) to 3 in conjunction with Article 65 paragraph (1) of the Criminal Code, but the sentence received by the child is too light, even thought this minor is protected, the criminal sanctions given should not be too light so that the child gets a deterrent effect, because the child has committed theft many times, causing disturbance to resident and harming other people.
Pengaruh Citra Merek, Persepsi Harga dan Kualitas Pelayanan terhadap Minat Beli Ulang Produk Es Teh Indoneisa
Authors: Andini Zagita , Shiratina Aldina
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh citra merek, persepsi harga, dan kualitas pelayanan terhadap minat beli ulang produk Es Teh Indonesia. Populasi dalam penelitian ini adalah seluruh konsumen yang pernah melakukan pembelian dan mengetahui Es Teh Indonesia. Sampel yang digunakan adalah yang pernah membeli Es Teh  Indonesia, Konsumen yang mengunjungi Es Teh  Indonesia gerai Srengseng, konsumen yang pernah membeli Es Teh  Indonesia minimal 2 kali pembelian. Sampel Penelitian yang digunakan sebanyak 140 responden menggunakan metode Purposive Sampling. Metode pengumpulan data menggunakan metode survei, dengan instrumen penelitian adalah kuesioner. Metode analisis data menggunakan Partial Least Square. (PLS 4.0). Desain penelitian ini adalah penelitian kausal dengan metode analisis data menggunakan PLS SEM. Penelitian ini membuktikan bahwa Citra Merek berpengaruh Positif dan signifikan terhadap Minat Beli Ulang, Persepsi Harga berpengaruh Positif dan signifikan terhadap Minat Beli Ulang dan Kualitas Pelayanan berpengaruh Positif dan signifikan terhadap Minat Beli Ulang. 
Kata Kunci: Citra Merek, Persepsi Harga, Kualitas Pelayanan, dan Minat Beli Ulang
Peran Kepuasan Kerja dalam Memediasi Pengaruh Konflik Kerja Terhadap Kinerja Karyawan
Authors: Sijabat Asiani
Published: December 2024

This study analyzes the effect of work conflict on employee performance embodied by job satisfaction. The sample used in this study amounted to 35 employees of PT. Mutiara Bakery Ambon. The technical analysis used is Partial Least Square (PLS). The results of this study showed that work conflicts did not have a significant effect on employee performance, The results also showed that work conflicts did not have a significant effect on employee satisfaction. Subsequently, job satisfaction has a significant effect on employee performance and the results show that job satisfaction mediates the influence of work conflict on employee performance
Legal Certainty of Inheritance for Children Born Out of Wedlock Who Are Recognized as Legitimate by Their Biological Parents
Authors: Putri Quine Khadra Merdeka
Published: December 2024

The birth of a child out of wedlock has a large and broad impact, namely whether or not to receive an inheritance, therefore it must receive legal protection in order to obtain clarity regarding the position and distribution of the inheritance. The purpose of this study is to analyze: 1). The legal status of obtaining inheritance rights for illegitimate children who receive legal recognition from their biological parents. 2). Legal protection for obtaining inheritance rights for illegitimate children who receive legal recognition from their biological parents. The approach method used in this study is normative juridical and supported by empirical juridical. The research specification used is descriptive analytical. The type of data uses primary data obtained through literature studies. The data analysis method used in this study is descriptive analysis. The results of the study concluded: 1). The Legal Status of an Illegitimate Child who receives legal recognition from his biological parents to obtain inheritance rights is to continue to receive the right to inherit, an illegitimate child who is recognized is entitled to a will grant as long as the grant does not harm other heirs and is in accordance with the provisions stipulated by the Law. Wirjono Prodjodikoro said that if an illegitimate child wants to receive legal recognition from his biological father, it must be based on the recognition and determination of the court. After receiving recognition and determination from the court, the illegitimate child has a civil relationship with his biological father and becomes an erfgenaam or legal heir according to law and statute and is entitled to receive inheritance from his biological father. 2). Legal Protection for Illegitimate Children who receive recognition from their biological parents to obtain inheritance rights is after the Constitutional Court (MK) Decision Number 46/PUU-VIII/2010, the heir has the right to file a lawsuit to the court to obtain his inheritance, of course it must be accompanied by concrete evidence that confirms having a blood relationship with the deceased testator. For example, a DNA test letter from a Forensic Doctor and a court decision that confirms the DNA test letter.
Duties and Authorities of the Sub-district Head as Temporary PPAT in Making Deeds Concerning Land (Study in Batang Regency)
Authors: Pratama Aditya Nur
Published: December 2024

Duties and authorities of the sub-district head as a temporary PPAT in making land deeds (study in Batang Regency) Land Deed Making Officers (PPAT) Notaries in Batang Regency have not yet reached sub-districts far from the city, this is a problem considering the vastness and spread of these areas. Therefore, in order to achieve equal legal certainty in the agrarian sector, especially land registration, once again the role of the sub-district head is still very much needed. The following problems arise: 1) Why are there no Sub-district Heads in Batang Regency who are Temporary PPATs?, 2) What is the role of the Sub-district Head who is appointed as Temporary PPAT in the Land Registration process in Batang Regency, Central Java?, 3) What are the obstacles faced by the Sub-district Head as a Temporary Land Deed Making Officer in the Land Registration Process in Batang Regency, Central Java? The objectives to be achieved from this study are: 1) To find out the reasons or factors that cause all Sub-district Heads in the Batang Regency, Central Java, not to become Temporary PPATs. 2) To find out what the roles of the Sub-district Head as a Temporary PPAT official are in the Land Registration Process in Batang Regency, Central Java. 2) To find out and examine the obstacles faced by the Sub-district Head in his role as a Temporary PPAT official in the Land Registration process in Batang Regency, Central Java. The results of the research and discussion on the implementation can be concluded: 1) The implementation of the duties and authority of the sub-district head as a Temporary PPAT in making land deeds in Batang Regency is carried out in accordance with the provisions of applicable laws and regulations, 2) Several obstacles faced by the Sub-district Head as a Temporary PPAT related to the implementation of duties and authority in making land deeds, 3) Efforts made by the Sub-district Head as a Temporary PPAT in overcoming obstacles faced during the implementation of duties and authority in making land deeds.
Implementation of Trusted Third Party in Cyber Notary Concept in Indonesia
Authors: Ganandhika Anak Agung Bagus Ryan , Pratama Putu Rama Ari , Putra Made Panji Ambara , Utama I Wayan Kartika Jaya
Published: December 2024

The purpose of this study is to determine the application of trusted third parties in the concept of cyber notary in Indonesia with two problems, namely the application of the concept of cyber notary and the application of trusted third parties in the concept of cyber notary increases the ease index by notaries in carrying out their duties. This study applies a method called the normative method because the legislation has regulated the concept of cyber notary. The results of this study refer to the concept of cyber notary interpreted solely as a digital transaction certificate, does not have strong legal force in Indonesia, but this cyber notary can be applied through UUJN which is regulated more deeply by being regulated in legislation.
Harmonization of Legislation in the Framework of ImplementationCyber Notary din Indonesia
Authors: Saputra Joshua Raymond , Christiana Darista Eny , Zahroh Addinar Fatimatus , Irianto Sigit
Published: December 2024

The writing of the law on Cyber Notary analyzes and aims at the current technological developments that will later affect the making of notarial deeds into electronic deeds but require a strong legal basis so that the deed has strong evidentiary power in accordance with applicable laws and regulations. Based on the results of research and discussion, it is known that the principle of facing a notary is stated in Article 16 paragraph (1) letter m while cyber notary is in Article 15 paragraph 3 of the UUJN. The principle of facing in the Cyber Notary concept is a consideration for utilizing electronic media via teleconference (virtual). The principle of facing virtually can be applied by considering the authority and obligations of the notary. With technology, everyone can face each other virtually. So that not only facing is interpreted conventionally but virtually using applications and still on the principle of caution so that the meaning of facing virtually can be applied in the Cyber Notary concept in Indonesia. The making of notarial deeds using the cyber notary concept has not yet obtained a legal basis so that it does not provide a guarantee of legal certainty. This legal research is included in normative legal research which is descriptive analytical in nature. The data sources used are secondary data consisting of primary legal materials, secondary legal materials. Data collection techniques by systematically collecting, reviewing and processing data originating from library materials and normative-qualitative data analysis documents.
A Young Patient with Coronary Artery Disease: Fortuity or Regularity?
Authors: Gogayeva Olena K. , Heneha Mariia B.
Published: December 2024

The aim. To analyze the reasons for hospitalization of young patients in the department of surgical treatment of coronary artery disease and to identify risk factors for premature progression of atherosclerosis.
Materials and methods. Retrospective analysis of data from patients younger than 45 years who were hospitalized in the department of surgical treatment of coronary artery disease of the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine in the period from September 2023 to September 2024. All the patients underwent standard clinical and laboratory examinations, electrocardiography, echocardiography, and coronary angiography, based on the results of which the heart team decided on further treatment tactics.
Results. Among 1187 patients who were hospitalized in the department during the year, 78 (6.57%) were younger than 45 years (mean age 40.7 ± 4.04 years). The admission was elective in 57 (73.1%) patients and urgent in 21 (26.9%) patients. During coronary angiography, hemodynamically significant lesions of the coronary arteries were detected in 45 (57.7%) patients, moderate (up to 50%) lesions of the coronary arteries in 22 (28.2%), intramural course of the left anterior descending artery in 6 (7.7%), and in 5 (6.4%) cases, coronary lesions were not detected. Coronary artery stenting was performed in 27 (60%) patients, coronary artery bypass grafting in 12 (26.6%) patients, which in 3 (25%) cases was supplemented by left ventricular aneurysm resection; myocardial revascularization was delayed in 6 (13.3%) patients.
Conclusions. The frequency of hospitalization of patients younger than 45 years with suspected coronary artery disease is 6.57%, among which cardiac surgery is required in 57.7%. Among the factors of premature progression of atherosclerosis of the coronary arteries, the role of diabetes mellitus (p = 0.0440), long-term smoking experience of 20.7 ± 7.9 years (p = 0.0002) and history of cerebral blood circulation disorders (p = 0.0478) was proven.
Mechanisms of Ischemic Heart Disease Development in Type 2 Diabetes Patients Based on Renal Function
Authors: Mankovskyi Georgii B. , Marushko Yevhen Yu. , Dzhun Yana Yu. , Stychynskyi Oleksandr S.
Published: December 2024

Ischemic heart disease (IHD) remains a leading cause of mortality and disability in Ukraine and globally, primarily due to stenosing atherosclerosis of the coronary arteries. Type 2 diabetes mellitus (T2DM) is a significant factor accelerating atherogenesis, alongside with chronic kidney disease. Investigating the causes of myocardial ischemia in patients with IHD, T2DM, and cardio-renal-metabolic syndrome requires further exploration.
The aim. To investigate the prevalence of various causes of myocardial ischemia in patients with IHD and T2DM based on renal function.
Materials and methods. The study involved 103 patients with IHD and T2DM examined at the Ukrainian Children’s Cardiac Center in 2023. Participants were divided into two groups: 52 with IHD, T2DM, and stage 3A or higher chronic kidney disease; and 51 with IHD and T2DM. All the patients had angina pectoris; myocardial ischemia was confirmed in 47 (45.6%) cases by stress echocardiography and in 56 (54.4%) via exercise electrocardiography testing. Echocardio­ graphy with intravenous dipyridamole was performed to diagnose coronary microvascular dysfunction and determine coronary flow reserve. Renal function was assessed using estimated glomerular filtration rate (eGFR) based on the CKD‑EPI score.
Results. Demographic indicators were comparable: 32 (61.5%) / 20 (38.5%) men/women in the clinical group and 30 (58.8%) / 21 (41.2%) in the control group (p > 0.05); the mean age was 56.3 ± 0.3 and 57.1 ± 0.4 years (p > 0.05). Patients with eGFR <60 ml/min/1.73 m2 had a lower frequency of single-vessel disease and a higher proportion of threevessel disease compared to those with eGFR ≥60 ml/min/1.73 m2. In all patients without significant coronary artery disease, coronary flow reserve was less than 2. In the clinical group, significant atherosclerotic lesions were the cause of IHD more frequently (86.5%) compared to the control group (64.7%), while microvascular angina had a significantly higher frequency (13.5% vs. 35.3%).
Conclusion. In patients with IHD, T2DM and reduced glomerular filtration rate (eGFR <60 ml/min/1.73 m2), more aggressive coronary artery disease was observed. Consequently, the proportion of microvascular dysfunction as a cause of myocardial ischemia was higher in patients with eGFR ≥60 ml/min/1.73 m2. Therefore, a comprehensive approach in managing patients with comorbid conditions becomes an even more relevant topic for further research aimed at improving prognosis.
Marital Status and Its Association with Leading Cardiovascular Risk Factors of Ischemic Heart Disease
Authors: Zhurba Oleg O.
Published: December 2024

The aim. To establish a relationship between marital status and frequency of cardiovascular risk factors: type II diabetes, hypertension, overweight, smoking, and hypodynamia.
Materials and methods. The study included patients with coronary artery disease (CAD) who underwent off-pump coronary bypass surgery. The total number of people in the sample was 3674, the mean age of the patients was 60.6 ± 0.8 years. Medical history, case records and results of general clinical and laboratory examinations provided for inpatient treatment became the material for analysis. The study design was based on the patient’s age according to the WHO age classification. The relationship between marital status and leading cardiovascular risk factors was calculated using the odds ratio and relative risk.
Results. As a result of studying the relationship between marital status as a leading factor in a person’s social status, it was established that the presence of a partner relationship was associated with a 1.50-fold increased risk of overweight (p = 0.0003, χ2 = 21.59), 1.07-fold increased risk of hypertension (p = 0.005, χ2 = 7.60) and 1.26-fold increased risk of type II diabetes (p = 0.04, χ2 = 4.28). Taking into account the age of the patients, it was found that senile married people had an increased risk of overweight (p = 0.0001, χ2 = 20.51) and elderly patients had an increased risk of hypertension (p = 0.002, χ2 = 9.73). It was found that loneliness in patients with CAD was associated with a 4.97-fold increase in the frequency of obese people (p = 0.08, χ2 = 3.02) and smokers (p = 0.0001, χ2 = 182.60). It was also determined that young single patients were significantly more likely to smoke (p = 0.0001, χ2 = 102.19).
Conclusions. As a result of the study, the associations of loneliness with leading cardiovascular factors regarding the risk of developing coronary heart disease were clarified. It was found that single persons, as a group with an unfavorable socio-economic status, had increased cardiovascular risks: obesity (p = 0.08, χ2 = 3.02) and smoking (p = 0.0001, χ2 = 121.16). It was also established that young single patients were significantly more likely to smoke (p = 0.0001, χ2 = 102.19), and elderly family patients had a significantly higher risk of overweight (p = 0.0001, χ2 = 20.51), and hypertension (p = 0.002, χ2 = 9.73).
Pengaruh Pemberian Ekstrak Peperomia pellucida Terhadap Penurunan Ekspresi Tumor Necrosis Factor Alpha (TNF-α) Pada Ginjal Tikus Wistar Jantan Yang Mendapat Pajanan Asap rokok
Authors: Nerawati Maria Fransiska , Farida Anggraini Soetedjo  , Heru Setiawan
Published: December 2024

Pendahuluan: Pajanan asap rokok menyebabkan stres oksidatif dan respons inflamasi melalui radikal bebas. Tumor Necrosis Factor Alpha adalah sitokin proinflamasi yang memperburuk peradangan ginjal. Pemberian antioksidan dan antiinflamasi eksogen diharapkan dapat mencegah cedera ginjal akibat pajanan asap rokok. Peperomia pellucida atau sirih cina, merupakan tumbuhan yang dikenal memiliki aktivitas antioksidan dan antiinflamasi. Penelitian ini bertujuan mempelajari efek ekstrak Peperomia pellucida terhadap penurunan ekspresi TNF-α pada ginjal tikus wistar jantan yang terpajan asap rokok. Metode: Penelitian true eksperimental ini menggunakan metode post-test only control group design dengan subjek tikus wistar jantan berusia 8-12 minggu yang diperoleh dari Laboratorium Hewan Coba Fakultas Kedokteran Universitas Wijaya Kusuma, Surabaya. Sampel terdiri dari 20 ekor tikus yang memenuhi kriteria inklusi dan eksklusi, dengan berat badan sekitar 180-200 gram. Data dianalisis menggunakan uji Mann-Whitney. Hasil: Uji Mann-Whitney menghasilkan perbedaan signifikan antara kelompok P1 dan P2, dengan nilai signifikan 0,025. Hal ini menunjukan  bahwa pemberian ekstrak Peperomia pellucida secara signifikan mampu menurunkan ekspresi TNF-α pada ginjal tikus yang terpajan asap rokok. Kesimpulan: Pemberian ekstrak Peperomia pellucida dengan dosis 400 mg/KgBB/hari dapat menurunkan ekspresi TNF-α pada ginjal tikus wistar jantan yang terpajan asap rokok.
Pengaruh Ekstrak Etanol Lada Hitam (Piper nigrum L) dan Serai (Cymbopogon citratus) terhadap Kadar Trigliserida pada Rattus Novergicus yang Hiperkolesterolamia
Authors: Silitonga Evanri Matthew , Noer Kumala Indahsari  , Herliani Olivia
Published: December 2024

Pendahuluan: Hiperkolesterolemia merupakan salah satu faktor risiko penyebab terjadinya penyakit jantung koroner. Di Indonesia, terdapat sekitar 36 juta penduduk atau sekitar 18% dari penduduk Indonesia yang menderita hiperkolesterolemia. Hiperkolesterolemia merupakan penyebab mortalitas yang tinggi yaitu sekitar 4 juta kematian per tahun. Kolesterol merupakan suatu komponen penting dalam tubuh manusia yang memiliki peran vital dalam berbagai fungsi. Kolesterol memengaruhi fluiditas membran sel dan berfungsi sebagai prekursor hormon steroid. Sebagian besar kolesterol dalam tubuh dibentuk melalui dua jalur utama, yaitu jalur eksogen yang berasal dari makanan dan jalur endogen yang disintesis di dalam tubuh. Lada hitam (Piper Nigrum L) telah lama digunakan dalam pengobatan tradisional untuk mengatasi berbagai masalah kesehatan, termasuk gangguan lipid. Kedua tumbuhan ini mengandung senyawa-senyawa aktif seperti polifenol dan flavonoid yang memiliki potensi dalam menurunkan kadar trigliserida. Cymbopogon citratus adalah tanaman tahunan aromatik yang penting secara ekonomi dari keluarga Poaceae. Tanaman ini ditanam di seluruh dunia dan memiliki catatan aplikasi terapi ekstensif selama satu abad dalam pengobatan tradisional dan Ayurveda di sejumlah negara.
Metode: Desain penelitian yang digunakan pada penelitian ini adalah eksperimental laboratorium dengan rancangan penelitiannya adalah post-test only controlled group design. Pada penelitian ini terbagi menjadi 6 kelompok, yaitu 3 kelompok kontrol berupa kelompok kontrol negatif (K-), kelompok kontrol positif (K+) dan kelompok perlakuan sebanyak 4 kelompok (P1, P2, P3, dan P4).
Hasil:  Hasil didapatkan rata-rata pengaruh ekstrak yang terbentuk pada kontrol negatif memiliki rata-rata sebesar 36,51, kontrol positif memiliki rata-rata sebesar 108.80, lada hitam 200mg memiliki rata-rata sebesar 66,02, lada hitam 500mg memiliki rata-rata sebesar 36,72, serai 200mg sebesar 50,26, dan serai 500mg sebesar 47,71.
Kesimpulan: Berdasarkan data statistik maka ekstrak lada hitam yang dapat menurunkan kadar trigliserida lebih baik adalah lada hitam dengan kadar 200mg sedangkan untuk ekstrak serai yang dapat menurunkan kadar trigliserida lebih baik adalah serai dengan kadar 200 mg.
Faktor Risiko Terjadinya Diabetes Melitus Tipe 2 di Puskesmas Wonomerto Kabupaten Probolinggo Tahun 2023
Authors: Malik Moch Lukman , I Made Subhawa Harsa  , Harya Narottama
Published: December 2024

Latar Belakang: Diabetes merupakan penyakit tidak menular yang cukup serius dimana insulin tidak dapat diproduksi secara maksimal oleeh pankreas. Di Indonesia, diabetes masih menjadi persoalan kesehatan yang cukup serius bahkan terus mengalami peningkatab jumlah penderita di setiap tahunnya seiring bertambahnya jumlah penduduk, pertambahan usia, meningkatnya gaya hidup tidak seehat, pola makan tidak sehat, diet yang tidak sehat, dan obesitas. Tujuan: penelitian ini untuk mengetahui faktor risiko yang dapat mengakibatkan diabetes melitus tipe 2 di Puskesmas Wonomerto Kabupaten Probolinggo. Metode: Penelitian ini menggunakan desain observasional dengan pendekatan cross sectional. Hasil: hasil pokok termasuk analisis statistik, dan Kesimpulan: Hasil penelitian menunjukkan bahwa faktor risiko seperti jenis kelamin, genetik, aktivitas fisik, dan pola makan memiliki hubungan terhadap kejadian diabetes mellitus tipe 2 di Puskesmas Wonomerto Kabupaten Probolinggo. Sedangkan, faktor risiko usia tidak memiliki hubungan terhadap kejadian diabetes mellitus tipe 2 di Puskesmas Wonomerto Kabupaten Probolinggo.