bluuebunny/crossref_metadata_2025 huggingface dataset:
Tác động của giáo dục khởi nghiệp, niềm đam mê và thái độ khởi nghiệp đến hành vi khởi nghiệp của sinh viên khối ngành kinh tế trên địa bàn tỉnh Đồng Nai
Authors: Lê Vũ Hà  , Lâm Ngọc Nhẫn  , Phạm Nguyễn Nguyên Hương  , Nguyễn Thị Kim Tuyến
Published: December 2023

Nghiên cứu được thực hiện với mục tiêu là xem xét tác động của các yếu tố giáo dục khởi nghiệp, niềm đam mê, thái độ khởi nghiệp đến hành vi khởi nghiệp, thông qua vai trò trung gian của ý định khởi nghiệp của sinh viên khối ngành kinh tế trong các trường đại học trên địa bàn tỉnh Đồng Nai. Kết quả thu thập từ khảo sát 296 sinh viên đại học được phân tích thông qua 2 phần mềm SPSS và SmartPLS, các giả thuyết của nghiên cứu này được kiểm định qua mô hình cấu trúc bình phương nhỏ nhất từng phần (PLS-SEM). Kết quả cho thấy các yếu tố đã đề xuất có tác động tích cực đến hành vi khởi nghiệp. Bên cạnh đó, ý định khởi nghiệp giữ vai trò trung gian của các yếu tố trên tác động đến hành vi khởi nghiệp.
Tổng hợp và đánh giá hoạt tính sinh học của một số dẫn chất (E)-3-(3,5-dicloro-2-hydroxyphenyl)-1-phenylprop-2-EN-1-ON
Authors: Vũ Thị Quỳnh  , Kim Ngọc Sơn
Published: December 2023

Các dẫn chất chalcon có nhiều hoạt tính sinh học như: kháng sốt rét, kháng viêm, kháng khuẩn, kháng nấm, kháng ung thư, chống oxy hóa... Trong nghiên cứu này, 4 dẫn chất chalcon CCA, CC4B, CC4M và CC4H3N được tổng hợp bằng phản ứng ngưng tụ Claisen-Schmidt giữa 4 dẫn chất của 1-phenylethanon và 3,5-dicloro-2-hydroxybenzaldehyd với xúc tác NaOH trong dung môi ethanol. Các chất tổng hợp được xác định độ tinh khiết bằng kỹ thuật sắc ký lớp mỏng và nhiệt độ nóng chảy, xác định cấu trúc bằng các phương pháp phổ IR, MS, 1H-NMR và 13C-NMR. Kết quả thử tác dụng kháng khuẩn cho thấy CCA, CC4M, CC4H3N có hoạt tính ức chế trên S. aureus. Ngoài ra, CC4H3N còn có hoạt tính trên P. aeruginosa. Khảo sát hoạt tính chống oxy hóa bằng phương pháp bắt giữ gốc tự do DPPH cho thấy CCA và CC4H3N có hoạt tính yếu.
السلوك المتفرج لدى طلبة المرحلة المتوسطة
Authors: م.م. طالب راشد كياس
Published: December 2023

يهدف البحث الحالي التعرف على مستوى السلوك المتفرج لدى طلبة المرحلة المتوسطة وعلى دلالة الفروق في السلوك المتفرج لدى طلبة المرحلة المتوسطة وفق متغير الجنس (ذكور، اناث)، وقد تحدد البحث بطلبة المرحلة المتوسطة في مدارس مركز مدينة الكوت محافظة واسط ، للعام الدراسي (2022-2023)، والبالغ عددهم (20728) طالباً وطالبة وتم اختيار عينة البحث بشكل عشوائي والبالغ عددها(300) طالب وطالبة، وقد استعمل الباحث الوسائل الإحصائية المناسبة وصولاً الى النتائج المطلوبة وتوصل الباحث الى النتائج الاتية:

يمتلك طلبة المرحلة المتوسطة درجة عالية من السلوك المتفرج.

توجد فروق ذات دلالة إحصائية في متغير السلوك المتفرج وفق متغير الجنس (ذكور، اناث) لصالح الاناث.
MODERN VIEW ON THE PERINATAL LESION OF THE CENTRAL NERVOUS SYSTEM IN NEWBORN CHILDREN (literature review)
Authors: Gasanov A.I. , Asadova T.A.
Published: December 2023

Prematurely born children with a syndrome of fetal growth delay is a large scientific research area in modern perinatology and neonatology. Despite progressive improvement of the perinatal care and development of early preventive methods of many pathological states, perinatal diseases and a neonatal mortality of children remains enough at the high level around the world. Results of the conducted researches prove that pathologies of the perinatal period often meets at prematurely born and children with very low body weight, playing the leading role in the elevation rate of mortality, social and biological dezataptation. It is proved that any changes considerably influence to activity of mother-placenta-fetus system, which is the uniform interconnected system. As a result of the infectious and noninfectious pathological processes which are happening in fetoplacental system, immediately influencing an embryonal development of a fetus, the brain is most often subject to pathological influence. Generally, nervous tissue and nervous cells are protected by a blood-brain barrier from destructive effect of the mediators circulating in the circulation during inflammatory processes.
THE OUTCOMES OF PREGNANCY IN WOMEN WITH EPILEPSY: THE RESULTS OF A RETROSPECTIVE STUDY
Authors: Magalov Sh.I. , Bagirova H.F. , Melikova Sh.Y.
Published: December 2023

A retrospective study of the outcomes of pregnancy and delivery based on the analysis of the case histories of 95 women with epilepsy during 5 years was carried out. A statistically significant prevalence of caesarean section in women with epilepsy in comparison with the control group (p<0.001) was identified. Analysis of the outcomes of delivery showed that epilepsy was an indication for caesarean section as the only factor or in combination with obstetrical indications in 54 (56.8±5.1%) cases. The incidence of premature rupture of membranes was significantly (p<0.001) higher in women with epilepsy, both those who received and did not receive antiepileptic drugs, compared with the control group. A significantly lowered Apgar scores in neonates born to women with epilepsy compared to controls was noted. Stillbirth has been observed in 2 (2.1±1.5%) women with epilepsy. The obtained results showed a very high rate of cesarean section (95.8%) and relatively low rate of practically healthy newborns (47.9%) in women with epilepsy. This indicates the need for more careful monitoring of pregnant women with epilepsy, the correct choice of antiepileptic drugs and their dose, pregnancy planning and prepregnancy counseling.
THE EFFECTIVENESS OF THE DRUG "NEOVIR" IN VIRAL ENCEPHALITIS IN CHILDREN OF EARLY AGE
Authors: Rashidova Sh.M. , Karagazova A.A. , Jafarova K.A. , Rajabov F.M.
Published: December 2023

One of the most widespread and severe types of neuroinfections are viral encephalitis. Due to its severity, high lethality, difficulties in diagnosis and unpredictability of outcomes, a special place of pathology takes place in young children. 43 sick children from 0 to 3 years with viral encephalitis were examined. The drug “NEOVİR” was included in the basic therapy. In patients with children who received this drug, the disease was without complications, there were no lethal outcomes, bed days were shortened. The obtained results testify to the effectiveness and safety of the inclusion in the therapy of the drug “NEOVİR”, with viral encephalitis in infants.
THE ROLE OF THE HORMONE ADIPONECTIN IN THE DEVELOPMENT OF DIABETIC POLYNEUROPATHY
Authors: Shiraliyeva R.K. , Heydarova N.H. , Ahmedova Z.G. , Orujova S.R.
Published: December 2023

One of the serious complications of diabetes, contributing to the development of disability and mortality, is diabetic polyneuropathy. Hyperglycemia causes disturbance of metabolic processes that trigger a cascade of metabolic disorders endoneural blood vessels, which in turn leads to disruption of supply of nerve fibers (hypoxia) and destructive changes of the latter. Adiponectin is a hormone gene associated with the development of type 2 diabetes and its complications. Identification of the genetic determinants of the development and progression of diabetic neuropathy will prevent the development of complications of type 2 diabetes - to diagnose and provide a personalized approach.
Predicting epileptic seizures with a stacked long short-term memory network
Authors: Pordoy Jamie , Zhang Ying , Matoorian Nasser , Zolgharni Massoud
Published: December 2023

Despite advancements, seizure detection algorithms are trained using only the data recorded frompast epileptic seizures. This one-dimensional approach has led to an excessive false detection rate,where common movements are incorrectly classified. Therefore, a new method of detection isrequired that can distinguish between the movements observed during a generalized tonic-clonic(GTC) seizure and common everyday activities. For this study, eight healthy participants and twodiagnosed with epilepsy simulated a series of activities that share a similar set of spatialcoordinates with an epileptic seizure. We then trained a stacked, long short-term memory (LSTM)network to classify the different activities. Results show that our network successfullydifferentiated the types of movement, with an accuracy score of 94.45%. These findings present amore sophisticated method of detection that correlates a wearers movement against 12 seizurerelated activities prior to formulating a prediction.
COVID-19 Pandemic: A Comparative Prediction Using Machine Learning
Authors: Sadik Rifat , Reza Md Latifur , Noman Abdullah Al , Mamun Shamim Al , Kaiser M Shamim , Rahman Muhammad Arifur
Published: December 2023

Coronavirus Disease 2019 or COVID-19 is an infectious disease which is declared as a pandemic by the World Health Organization (WHO) have a noxious effect on the entire human civilization. Each and every day the number of infected people is going higher and higher and so the death toll. Many of country Italy, UK, USA was affected badly, yet since the identification of the first case, after a certain number of days, the scenario of infection rate has been reduced significantly. However, a country like Bangladesh couldn't keep the infection rate down. A number of algorithms have been proposed to forecast the scenario in terms of the number of infection, recovery and death toll. Here, in this work, we present a comprehensive comparison based on Machine Learning to predict the outbreak of COVID-19 in Bangladesh. Among Several Machine Learning algorithms, here we used Polynomial Regression (PR) and Multilayer Perception (MLP) and Long Short Term Memory (LSTM) algorithm and epidemiological model Susceptible, Infected and Recovered (SIR), projected comparative outcomes.
Increased number of major amputations during pandemic could be caused by patients’ fear of COVID-19
Authors: Figl Josip
Published: December 2023

Objective. To prove or discard the thesis that lessening of number of patients who went to the surgeon’s check-ups even if it led to major amputations of their leg was caused by fear of COVID-19 pandemic. Methods. A retrospective data analysis in a single institution, a tertiary health care centre. Results. The data revealed a significant decrease in number of patients who went to the surgeon’s check-up and increase of major amputations in Corona virus period in four months of most actual COVID-19 pandemic time in Croatia. Conclusion. The patients’ fear of pandemic thesis might best explain this kind of patients’ behaviour.
Case Reports: Endovascular Treatment of Cerebral Venous Sinus Thrombosis
Authors: Takeuchi Masataka , Uyama Atsushi , Matsumoto Takashi , Tsuto Kazuma , Goto Tadateru , Konishi Yoshifumi
Published: December 2023

Background: The causes of cerebral venous sinus thrombosis (CVST) are diverse, and headache is the only symptom in mild cases. However, in severe cases, perfusion disorders may concomitantly cause intracerebral hemorrhage, resulting in serious complications. Herein, we report two severe CVST cases in which good outcomes were obtained following endovascular treatment. Patients and Methods: Case 1. A 42-year-old man consulted an ophthalmologist with a chief complaint of decreased vision. The patient had a considerably high intraocular pressure and papilledema. However, due to unknown etiology, he was only prescribed eye drops. He subsequently developed headaches and experienced an alteration in his. An urgent surgery was performed with using the pull-back technique using a suction catheter, following which, the patient’s neurological symptoms improved. Case 2. A 50-year-old man was transferred to our hospital with a chief complaint of generalized clonic convulsions. The patient was diagnosed with venous sinus thrombosis. Attempts were made to crush the thrombus with a percutaneous transluminal angioplasty balloon and aspirate the thrombus with an aspiration catheter. However, thrombus removal and recanalization could not be achieved. Subsequently, a thrombectomy was performed using the FilterWire technique with a distal embolic protection device. Anterograde blood flow was restored, and the convulsive seizures disappeared. Conclusion: Venous perfusion injury should be avoided in severe cases of CVST, and endovascular treatment using various devices is a therapeutic option in such cases.
Difficulties of contemporary motherhood. Methodological aspects of maternal research
Authors: Lewicka Monika
Published: December 2023

Wprowadzenie. Celem artykułu jest przedstawienie trudności doświadczanych przez matki podczas pierwszej fali pandemii COVID-19. Zakładano, że w czasie pandemii nasilą się trudności związane z godzeniem życia zawodowego i rodzinnego, nastąpią zmiany w relacjach między matką a dzieckiem, zmieni się podział obowiązków rodzinnych między rodzicami dziecka. Cel. Zapytano o główny problem: Jakich trudności związanych z życiem rodzinnym w czasie pandemii wywołanej wirusem SARS-CoV-2 doświadczają badane matki? Materiał i metody. W badaniu zastosowano podejście jakościowe. Źródłem danych badawczych są wywiady z matkami. Wyniki. W czasie pandemii trudności matek miały zróżnicowany charakter. Wyniki badań wskazują zarówno na negatywne, jak i pozytywne (od pogorszenia do poprawy relacji) konsekwencje zmiany relacji między matką a dzieckiem, próby łączenia życia zawodowego z rodzinnym oraz podziału obowiązków między partnerami. Badane matki zgłaszają wzrost napięcia i stresu w wyniku pojawiającego się konfliktu między pracą zawodową a życiem rodzinnym, ograniczonego wsparcia ze strony partnera oraz trudnej, pełnej trudnych emocji relacji z dzieckiem. Na drugim kontinuum znajdują się matki, które pomimo trudnej sytuacji starały się godzić życie zawodowe z rodzinnym, otrzymywały wsparcie ze strony partnera, dzieliły się po równo obowiązkami związanymi z opieką nad dzieckiem i prowadzeniem gospodarstwa domowego. Wnioski. Pandemię należy rozpatrywać w kategoriach sytuacji trudnej. Niejako wymusiła ona na matkach skonstruowanie nowej codzienności związanej z rolą matki i pracownika jednocześnie. Dotychczasowe próby równoważenia obu sfer życia prowadzące do zachowania równowagi (work-life balance) nie zawsze okazywały się skuteczne w czasie pandemii. W wielu przypadkach pandemia doprowadziła do zresetowania dotychczasowego modelu rodziny i stworzenia go na nowo.
Construction of public schools in the wileńskie voivodship in the Second Republic of Poland. Results of preliminary research
Authors: Jurczyk-Romanowska Ewa , Piwowarczyk Mirosław , Walasek Stefania
Published: December 2023

Wprowadzenie. W latach 1918–1939 zagadnienie budownictwa szkół, przede wszystkim powszechnych, stało się priorytetowym zadaniem dla państwa, samorządów i lokalnych społeczności. Wprowadzenie ustawowego obowiązku nauki skutkowało koniecznością budowy szkół w licznych miejscowościach. Wiązało się to z pokonywaniem szeregu problemów przede wszystkich o charakterze finansowym. Celem artykułu jest zaprezentowanie przebiegu procesu budowy szkół, ich wzrastającej liczebności oraz źródeł finansowania. Cel. W artykule nakreślono rozwój budownictwa szkół powszechnych na terenie województwa wileńskiego w latach II RP. Badania obejmowały analizę zróżnicowanych dokumentów w zakresie rozwiązań legislacyjnych na poziomie państwa, działalności lokalnej, a także wsparcia działań miejscowych przez organizacje i towarzystwa ogólnopolskie. Metoda. W prowadzonych badaniach wykorzystano metodę jakościowej analizy dokumentów. Zróżnicowany materiał źródłowy został zgromadzony zarówno podczas kwerendy archiwalnej w Wilnie, jak i kwerendy powszechnie obowiązujących aktów prawnych dokonanej za pośrednictwem Internetowego Systemu Aktów Prawnych.
Wyniki. W artykule wskazano liczbę wybudowanych szkół w okręgu wileńskim w latach II RP oraz podjęto próbę zrekonstruowania ich finansowania. Wnioski. Efektem budowy (rozbudowy i remontów) szkół w II RP było: 1) rozwijanie sieci szkolnictwa zaniedbanego w czasach zaborów oraz zniszczonego w czasie działań prowadzonych podczas I wojny światowej i w latach 1918-1920; 2) tworzenie warunków
dla coraz pełniejszej realizacji obowiązku szkolnego; 3) organizowanie centrum życia kulturalno-oświatowego lokalnej społeczności; 4) aktywizowanie i integrowanie mieszkańców danej miejscowości.
Ensayo sobre los Constructos de Bienestar y Felicidad
Authors: Betalleluz Joel
Published: December 2023

Este ensayo recopila y expone principales aportes de distintos autores enfocados en el estudio del bienestar y la felicidad. La discusión de estos dos términos también incorpora otros como placer, utilidad, satisfacción del deseo, y satisfacción con la vida. Además, se intenta comprender el vínculo entre el ingreso y todos estos términos mencionados. Por otro lado, se comenta cómo la Economía optó por alejarse de la Ética por cuestiones de simplicidad en la concepción del hombre como agente económico, mas no moral. Se discute también visiones objetivistas y subjetivistas respecto del bienestar y la felicidad, así como las medidas subyacentes en cada visión.Finalmente, se derivan reflexiones a partir de lo discutido en todo el ensayo.
Sobre la Democracia y el Crecimiento Económico
Authors: Ayala Alfonso
Published: December 2023

Este artículo presenta una recopilación y análisis de la literatura empírica que estudia el impacto económico que implica la influencia del régimen democrático en dos variables claves en economía: crecimiento económico y desigualdad. Si bien el concepto de democracia es multidimensional, es de amplia importancia aproximarse a su relación con el crecimiento económico, asimismo se presentan de manera breve los mecanismos asumidos en las diferentes especificaciones. Si bien la mayoría de la especificaciones descansan en el modelo de mínimos cuadrados ordinarios de sección cruzada, se han discutido y utilizado de manera complementaria otros métodos de estimación, se ha realizado diversos experimentos de especificación. En el presente trabajo se ha seleccionado la principal especificación de la relación democracia y crecimiento de cada trabajo, complementariamente se realiza lo mismo para la relación democracia y desigualdad.
Volatilidad y Ratio de Violación en la Efectividad del VaR: el Caso de los Fondos Tipo III de las AFP en el Perú
Authors: Palomino Carlos
Published: December 2023

Nuestro estudio aplica el método de backtesting al Fondo Tipo III de Administradoras de Fondos de Pensiones en Perú (AFPP) para evaluar la efectividad de los modelos de generación en el Valor en Riesgo (VaR) cuando se pronostica el VaR. Los Fondos Tipo III son las carteras que mantienen los activos más volátiles que administran las AFPP. Nuestro artículo ha tomado diferentes períodos que incluyen la crisis financiera 2007-08 y el shock debido a la pandemia COVID 19. Nuestros resultados confirman que los modelos de pronóstico de riesgo dependiente del tiempo como el EWMA y GARCH-Normal son adecuados para evaluar VaR cuando usamos LR (cobertura), pero no son muy precisos para el test de Independencia.
“A Gale of Hope for Latin America”
Authors: Fernández Susana S. , Mattos Ana Paulla Braga
Published: December 2023

The terms esperanza (Spanish) and esperança (Portuguese) (‘hope’) are frequently used in the political and social discourse of Latin America. In this vast region, plagued by recurrent political and economic crisis and other social challenges, the feeling of hope, but also its counterpart, lack of hope/hopelessness, is present in mass media, social media, the discourse of politicians and other public figures, as well as in the urban landscape, and represents the spirit of people who are not ready to give up on a brighter future. We propose that the terms esperanza/esperança are cultural keywords in Latin America. For our analysis, we have chosen two countries, Argentina and Brazil, to carry out a corpus study. We focus mainly on Twitter data, but we also include other written media to identify the most salient semantic and pragmatic features of these words and their importance in these Latin American countries. As part of the analysis, we look into possible differences between Spanish and Portuguese—that is, differences in use in the selected countries.
NSM-based Cultural Dictionaries
Authors: Sadow Lauren
Published: December 2023

For language learners, the transition from classroom to immersion is an exhausting and difficult one. Not least because of how language is used differently “in the real world” to how it is taught in classrooms. There are many “insider” dictionaries of language but few dictionaries which take a closer look at the important words and explain them in ways that learners can understand. Natural semantic metalanguage (NSM)’s way of defining culturally important terms and combining them with cultural scripts gives us an opportunity to go beyond the standard realm of definitions and explore the possibilities of what I am calling “cultural dictionaries”. This paper will discuss the current opening in learner lexicography to include emic cultural information. It will then discuss how NSM can contribute to such lexicographical practice. Finally, drawing on the first NSM-based cultural dictionary project—the Australian Dictionary of Invisible Culture for Teachers—it provides reflections, advice, and recommendations for future cultural dictionary projects.
Narrativa transmedia y transcultural. Adaptando el arquetipo del héroe vengador en El Lobo Solitario y su cachorro y Camino a la Perdición
Authors: Sánchez López Pablo
Published: December 2023

Las adaptaciones entre industrias creativas son una de las tendencias más importantes ahora mismo en la cultura popular contemporánea. A partir de un análisis narrativo y estético, este artículo se centra en un estudio de caso transcultural y transmedia: una doble adaptación que parte de un manga japonés, El Lobo Solitario y su Cachorro, y su traslación a novela gráfica en EE.UU., Camino a la Perdición; y que a su vez es convertida en una película de Hollywood del mismo título. El recorrido entre estas tres obras tiene como hilo conductor un arquetipo narrativo, el del héroe vengador, que servirá como ejemplo de cómo estructuras, ideas y tropos sobre la venganza cambian o se mantienen cuando un mismo relato es narrado en diferentes medios y culturas
Literatura en la universidad. Lectura lúcida y escritura creativa
Authors: Ballesteros Panizo Mapi
Published: December 2023

La lectura y la escritura son actividades irremplazables para la formación del ciudadano en una sociedad moderna y democrática, de individuos libres que poseen un elevado autoconocimiento. Se comprende que la reducción de la formación lingüística y literaria de la población ha sido uno de los rasgos más regresivos (por deshumanizadores) de los últimos tiempos. Y a la inversa, su incipiente rehabilitación actual abre perspectivas de trabajo positivo a quienes detectamos el poder humanizador del lenguaje.
En este artículo se sostiene la idea de que no hay mejor manera de enseñar a escribir que enseñando a leer, porque escribir y leer son actividades recíprocas (Roca, 2021). Partiendo de esa premisa, se va a proponer una pedagogía del texto literario basada en las tres fases de la hermenéutica de Ricoeur (1980): comprender, explicar y aplicar. La comprensión de la estructura (morfo)-lógica, la explicación de la validez de la interpretación -y su discusión-, y la aplicación, que se refiere a la capacidad de unir horizontes y de ampliarlos a través del diálogo, de una actitud que deja manifestarse a la obra y que invita, al lector, la escritura creativa (Galvan, 2004, Montilla-Narváez, 2021). Esta manera de estudiar la obra literaria centrada en el concepto de aplicación proporciona orientaciones para un pluralismo abierto a la esencia de las obras, incentiva el pensamiento crítico y permite la emergencia de procesos de mejora y transformación (Bain, 2006; Aguirre-Romero, 2019; Roca, 2021). En el capítulo se detallarán los vértices sobre los que se sustenta la aplicación didáctica de esta teoría (la teoría de la complejidad de la competencia comunicativa, el aprendizaje basado en problemas y la hermenéutica literaria).
Traducción creativa, transcreación literaria, composición musical y tópicos literarios en el aula de filología o cultura clásica
Authors: Padilla-Carmona Carles
Published: December 2023

En este trabajo exponemos un ejemplo de buenas prácticas innovadoras basado en una experiencia docente con estudiantes del ‘Grado en traducción y mediación interlingüística’ de la Universitat de València. La actividad consiste en identificar los tópicos literarios clásicos en diferentes composiciones poéticas o musicales contemporáneas en cualquier idioma objeto de estudio (español, catalán, inglés, francés, alemán o italiano) y después traducir los textos seleccionados a dos o más lenguas, respetando no solo el contenido, sino todos los aspectos formales como estructura, métrica (número de sílabas y combinación del acento de intensidad con el ritmo musical, en su caso) y rima, principalmente. Cuando se trata de composiciones musicales, los alumnos interpretan en directo ante la clase sus propias versiones.
Palabras clave
Traducción creativa, transcreación, composición musical, tópicos literarios
 
Summary
In this paper we present an example of innovative good practices based on a teaching experience with students of the 'Bachelor Degree in translation and interlinguistic mediation' of the University of Valencia. The activity consists of identifying the classic literary topics in different contemporary poetic or musical compositions in any language under study (Spanish, Catalan, English, French, German or Italian) and later translating the selected texts into two or more languages, respecting not only the content, but all the formal aspects such as structure, metrics (number of syllables and combination of intensity accent with musical rhythm, if applicable) and rhyme, mainly. When it comes to musical compositions, students perform their own versions live in front of the class.
Keywords
Creative translation, transcreation, songwriting, literary topics
Sinful, Sexual, Sacred: Locating a Thirteenth-Century Visuality through the Selective Erasures in Rylands MS French 5
Authors: Lewis Molly
Published: December 2023

Rylands MS French 5 is a thirteenth-century Bible picture book consisting of a
single pictorial cycle depicting scenes from the Old Testament. The manuscript
is remarkable for the predominance of its imagery and the erasures that
selectively mar its otherwise unspoiled folios. The sites of these erasures can
be categorised as evil, obscene, and divine subjects. Examining each in turn, I
hope to demonstrate the importance of both the Bible picture book tradition and
manuscript erasure for considerations of later medieval visuality. Where the
Bible picture book encapsulates thirteenth-century confidence in the visual
sense, the erasures signal the boundaries of this confidence, revealing a
paradoxical mode of sight in which ocular passions merge and clash. In turn,
these findings problematise attempts to theorise a homogenous thirteenth-century
visuality, as different understandings of vision surfaced in the decades after
the production of MS French 5 and played out in impassioned and contradictory
ways on the manuscript page.
On the Pedagogical Priorities of Teachers-vocalists of the Initial Period of Activity of the Saratov Conservatory
Authors: Rudyakova Alla Eduardovna
Published: December 2023

The object of this study is the initial period of activity of the Saratov Conservatory; the subject can be called the pedagogical priorities of vocal teachers of this period under consideration. In the article, based on rare archival data, surviving printed evidence, and student memoirs, an attempt is made to restore the pedagogical priorities of the most famous and influential in the musical circles of Moscow and St. Petersburg, active participants in concert events of the Imperial Russian Musical Society: Mikhail Efimovich Medvedev - the first performer of the role of Lensky in the opera P. I. Tchaikovsky's "Eugene Onegin" and Alevtina Mikhailovna Paskhalova, who embodied the image of the Snow Maiden in the opera of the same name by N. A. Rimsky-Korsakov. The scientific novelty of the study includes the fact that the author identifies and for the first time introduces into scientific circulation data on the pedagogical priorities of the most prominent vocal teachers who have made a significant contribution to improving the educational process of the department of academic singing. It is revealed that the pedagogical priorities of M. E. Medvedev and A. M. Paskhalova include: a fairly low type of breathing, increased attention to developing a sense of support for sound, a cautious attitude towards the development of the full range of the voice, the development of clear diction, evenness of sound production, smoothness of register transitions; soft sound attack; the ability to qualitatively vocalize various dynamic gradations of sound; the use of the “concentric” teaching method in the pedagogical process, increased attention to the education of the emotional and dramatic component of the performer’s personality. The analysis also showed that the features that distinguish the pedagogical views of the professors of the initial period of the Saratov Conservatory include the use of the repertoire of Russian composers in class work with a beginning singer.
Pierre van Houwe and his concept of "Playing with Music" in the history of music education
Authors: Karamanova Marina Leonidovna , Asriyan Alina Gavrilovna
Published: December 2023

The object of research of this work is the creative and pedagogical activity of the Dutch conductor, composer and teacher Pierre van Hauwe (1920-2009). The subject of the study is the conceptual foundations of his pedagogical theory of "Playing with Music", which has become widespread not only in European countries, but also in South America, Africa and Asia. The authors of the article consider in detail the features of P. van Hauwe's concept, the foundations of which are based on the elements of the Zoltan Kodai system, which became widespread in Hungary, and the method of musical education of Karl Orff, whom P. van Hauwe met in Salzburg. Special attention is paid to the methodical publication "Playing with Music" ("Spielen mit Musik"), where P. van Hauwe outlined his concept step by step, accompanied by specific recommendations for teachers. The research used theoretical (analysis, synthesis, etc.) and empirical (comparative-historical, structural-typological) research methods. The main conclusions of the study: P. van Hauwe's pedagogical activity had a great impact on the development of music education not only in the Netherlands, but also in other countries of the world. His concept of "Playing with music" ("Spielen mit Musik") combined elements of the educational systems of two outstanding teachers of the twentieth century – Z. Kodai and K. Orff, as a result of which it became a natural continuation of the development of European musical and pedagogical thought. A special contribution of the authors of the article to the study of the topic, reflecting its novelty, was a detailed analysis of the methodological publication "Spielen mit Musik" ("Playing with music"), on the basis of which the essential relationship of the ideas of P. van Hauwe and his predecessors was revealed. Also, for the first time in Russian musicology, the facts of the musician's biography are more fully disclosed.
Forecast of the development of thermal erosion processes in the Yamalo-Nenets Autonomous Okrug under modern climate changes
Authors: Bogatova Daria Maksimovna , Alyautdinov Ali Raisovich , Zheleznova Irina Vladimirovna , Kislov Aleksandr Viktorovich , Shishov Andrei Aleksandrovich
Published: December 2023

The study of exogenous processes and their effects on natural and anthropogenic systems is a very important aspect for the development of Arctic territories. One of these processes is thermal erosion, which is widespread in the Yamalo-Nenets Autonomous District due to the presence of permafrost in the vast majority of its area. The main prerequisites for the manifestation of thermal erosion processes can be divided into several groups of factors. Firstly, the geomorphological characteristics of the territory play a key role: the lengths and slopes. Secondly, the lithological and granulometric composition of rocks, as well as ice content and temperature, determine the resistance of the soil to the thermal and mechanical effects of flowing water. Thirdly, the amount of precipitation is an important factor, especially precipitation in winter and heavy rainfall in summer. They contribute to a high concentration of runoff in short periods of time, which leads to rapid destruction of rocks and the removal of large volumes of loose material. Finally, the fixation of the top layer of soils by the root system can be considered the main reason that counteracts the development of thermal erosion. The purpose of this study is a prognostic assessment of the risks of the development of thermal erosion processes in the context of the observed climate warming. To assess the risks, data from climate modeling of the Yamalo-Nenets Autonomous District for the middle of the XXI century were used for an ensemble of climate models included in the CMIP6 project. The analysis of Google Earth satellite images and information about the geological and geomorphological features of the region are used for zoning the territory in terms of dynamics and dangers of thermal erosion. The result of the study was the compilation of a map of the Yamalo-Nenets Autonomous District by categories of risks associated with thermal erosion processes. It is shown that in the perspective of several decades, more than 50% of the region's area is subject to intensification of thermal erosion destruction of soils, which requires careful planning of economic development and design of protective structures. An attempt has been made to assess the impact of erosive and thermoerosive effects on the natural environment of the Yamalo-Nenets Autonomous Okrug due to climate change using the recommendations of this assessment by Order of the Ministry of Economic Development of the Russian Federation dated 05/13/2021 N 267. Climatic factors can seriously enhance the causes and negative consequences of the development of thermoerosion, while local manifestations should be assessed using field data based on the calculation methods.
Positron Trapping Rate in Some Ferroelectrics, Semiconductors and Glasses
Authors: Peneva Stela , Troev Troyo
Published: December 2023

This paper presents comparative results of positron spectroscopy studies in ferroelectrics, semiconductors and glasses. The positron lifetime spectroscopy study is focused on the investigation of the positron trapping rate in the ferroelectrics, the Triglycine Sulphate (TGS) (NH3CH2COOH)3H2SO4, Rochelle Salt (RS) NaKC4H4O64H2O and Potassium Dihydrogen Phosphate (KDP) KH2PO4 structures, semiconductors and glasses. The positive positron charge opens the possibility for determining the changes in charge states in technologically important order-disorder ferroelectrics. The positron lifetime spectroscopy (PLS) results show that the second lifetime component as a function of temperature in order-disorder ferroelectrics TGS, RS and KDP is due to the positron trapping in negatively charged defects of ferroelectric. The PLS analysis has been applied for examination of positron trapping in the electronicdefect structure in selected ferroelectrics materials, semiconductors and glasses.
Detection of OXA-23 Gene in Amoxicillin-Clavulanic Acid-resistant Proteus mirabilis Isolates in Turkey
Authors: Vural Demet , Ulker Kubra , Cayci Yeliz , Bilgin Kemal , Birinci Asuman
Published: December 2023

Class D carbapenemases, including OXA-23, OXA24/40, OXA-51, OXA-58, and OXA143, are typically associated with Acinetobacter species; OXA-48-like carbapenemases are usually found in Enterobacterales isolates. Although a few studies on Acinetobacter-type OXA genes in Enterobacterales have been reported, the presence of these Acinetobacter-type OXA genes in these isolates is quite limited. In contrast to other Enterobacterales isolates, studies have identified the presence of genes OXA-23, OXA-24, OXA-51, and OXA-58, which are typically associated with Acinetobacter species, Proteus mirabilis. This study aimed to investigate the presence of carbapenemase genes in amoxicillin-clavulanic acid-resistant P. mirabilis isolates. Thirty-two P. mirabilis isolates isolated from samples sent from intensive care patients and resistant to amoxicillin-clavulanic acid were included in the study. Vitek MS was used for bacterial identification, and the antibiotic resistance profile was determined by the Vitek 2 automated system. The presence of Acinetobacter type OXA genes (OXA-23, OXA-24, OXA-51, and OXA-58) and OXA-48, KPC, NDM, VIM, and IMP genes in P. mirabilis strains were investigated by polymerase chain reaction (PCR) method. In addition, ESBL production was detected in carbapenemase gene-positive isolates. According to the PCR results, while the presence of the OXA23 gene was detected in 15.6% of the isolates, the presence of OXA-24, OXA-51, OXA-58, OXA-48, KPC, NDM, VIM and IMP genes was not detected in any of the isolates. OXA-23, OXA-24, OXA-51, and OXA-58 are common carbapenemases in Acinetobacter species, especially OXA-23 is very common. However, these genes are very rare in Enterobacterales isolates. There are studies in which these genes were identified in P. mirabilis isolates. Similarly, in our research, the OXA-23 gene was detected in P. mirabilis isolates. To our knowledge, this is the first OXA-23 positivity reported in P. mirabilis isolates from our country.
Seismicity in the Bransfield Strait, Antarctica, for the Period 2020–2023 as Recorded from LIVV Seismic Station
Authors: Buchakchiev Valentin , Dragomirov Dragomir , Pandourska Elitza , Georgieva Gergana , Dimitrova Liliya
Published: December 2023

The Bransfield Strait is situated between the Antarctic Peninsula and the South Shetland Archipelago. The seismic regime of the area is characterized by volcanic and tectonic activity, expressed in shallow, weak to moderate earthquakes. The global seismic networks locate the stronger earthquakes in this region. Weak events are recorded by standalone stations installed on the Antarctic continent and neighbouring islands, the number of which is not sufficient for good location. In the study, we present the processing of the seismic data for the period from January 2020 to January 2023 registered by Bulgarian Antarctic station LIVV and the produced results. The single-station localization method was applied and calculated, epicentres were compared with those listed in the European Mediterranean Seismological Centre catalogue. In the study period, the seismic pattern is dominated by swarm volcanic seismicity around Orca volcano, as well as three earthquake clusters of unknown origin in the vicinity of Livingston Island.
Power Efficient Implementation of ECC Using LCSLA Based Dual Field Vedic Multiplier
Authors: Sengottaiyan Senthil , Subramaniam Vadivel , Thangavel Yuvaraja , Sekar Karthick
Published: December 2023

The Elliptic Curve Cryptographic (ECC) technique is employed for security standards such as Security Key Management (SKM), digital signature, data authentication and so on. The ECC technique is capable of sequential and parallel mode processes through a unified design. It is used for both equally binary fields and prime fields of cryptosystems. The DMM structure has been developed using CSA. This adder requires a greater amount of Full Adder circuits, which occupy more area. To overcome this problem, this paper discusses four different methods, such as DMM-Optimized Carry Look Ahead Adder, DMM-Optimized Carry Bypass Adder, DMM-Look up Table Carry Select Adder, and Dual Field Vedic Multiplier – LCSLA, which is used to increase the performance of the ECC. The parameters like power utilization, time delay information, and hardware area overhead are analyzed and compared with existing methods. Among those four methods, the DVM-LCSLA method gave better results in FPGA and ASIC performances.
New Insight into Enzyme Inhibitory and Anti-proliferative Activity of Echinops ritro L. (Asteraceae)
Authors: Balabanova Vessela , Zheleva-Dimitrova Dimitrina , Voynikov Yulian , Zengin Gokhan , Joubert Olivier , Gevrenova Reneta
Published: December 2023

Echinops ritro L. is a perennial herbaceous plant in the tribe Cardueae, Asteraceae family, widely distributed, up to 1000 m a.s.l. In the present study, the enzyme inhibitory and anti-proliferative activity of E. ritro leaves and flowering heads extracts were assayed. Quantitative determination of 22 analytes, including eleven acylquinic and one hydroxycinnamic acids, and ten flavonoids was performed by Ultra high-performance liquid chromatography – diode array detector (UHPLC-DAD) analyses. The major compound was 1,5-dicaffeoylquinic acid, being presented at $$20.48\pm 0.22$$ µg/mg in the flowering heads, while the leaves demonstrated very high levels of chlorogenic acid ($$117.29\pm 14.20$$ µg/mg) and 3,5-dicaffeoylquinic acid ($$12.79\pm 0.282$$ µg/mg). The flavonoids were dominated by isoquercitrin and rutin ($$3.13\pm 0.033$$ and $$3.25\pm 0.057$$ µg/mg, respectively) together with metoxylated aglycones nepetin, hispidulin and jaceosidin (up to 0.51 µg/mg). The leaves extract revealed prominent acetylcholinesterase ($$2.33\pm 0.09$$ mg GALAE/g) and α-glucosidase inhibitory potential ($$0.37\pm 0.01$$ mmol ACAE/g). Nevertheless, the flowering heads extract showed distinct butyrylcholinesterase ($$1.41\pm0.35$$ mg GALAE/g), tyrosinase ($$45.66\pm0.84$$ mg KAE/g), amylase ($$0.37\pm0.02$$ mmol ACAE/g), and lipase ($$9.06\pm1.43$$ mg OE/g) inhibitory activity. The anti-proliferative assay was completed towards THP-1 monocyte leukemic cells, where at a concentration $$>1000$$ µg/mL, a significant dose dependent reduction of cell viability was observed for the leaves extract. In conclusion, the data revealed a new insight into the taxon for its health benefit application.
Characterizing Morphometric and Nanomechanical Malignant Cell Features in a Rare Paediatric γδ T-acute Lymphoblastic Leukaemia: Insights from a Single Case Study Using Atomic Force Microscopy
Authors:   Department of Paediatric Haematology and Oncology, University Hospital “Queen Joanna”, 8 Byalo More Str., Sofia, Bulgaria, Bachvarov Konstantin , Strijkova Velichka ,   Institute of Optical Materials and Technologies “Acad. Jordan Malinowski”, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 109, Sofia, Bulgaria, Antonova Borislava ,   Medical Faculty, Medical University – Sofia, 2 Zdrave Str., Sofia, Bulgaria, Jordanova Maya ,   Department of Paediatric Haematology and Oncology, University Hospital “Queen Joanna”, 8 Byalo More Str., Sofia, Bulgaria, Dimitrov Yoan ,   Medical Faculty, Medical University – Sofia, 2 Zdrave Str., Sofia, Bulgaria, Todinova Svetla ,   Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 21, Sofia, Bulgaria
Published: December 2023

The most common cancer in paediatric age is acute lymphoblastic leukaemia (ALL) which accounts for nearly a quarter of all cases of paediatric cancer. ALL cases are classified as B-cell or T-cell precursor ALL, based on their immunophenotypical features. Patients with T-cell ALL (T-ALL) comprise 10–15% of all newly diagnosed cases and are more prevalent in boys and in older age compared to the overall incidence peak age of ALL. In this case report, we present the morphometric and nanomechanical features of T-lymphoblasts derived from an 11-month-old infant with a rare subtype of γδ T-ALL with aggressive biological behavior. To investigate these features, we employed atomic force microscopy (AFM) and compared the blast cell deviations found in their nanostructure and elasticity to those of normal lymphocytes from a healthy child. The malignant T-lymphoblasts exhibited reduced roughness and Young’s modulus values. This single case analysis demonstrates the potential of the AFM method to provide additional information regarding the characteristics of malignant cells and suggests its potential as a complementary approach for distinguishing neoplastic cells from normal cells. The application of AFM could potentially facilitate the introduction of in vitro tests to determine the efficacy of anti-leukemic treatments.
Cuboid Cobbles Hinder Elite Youth Football Player
Authors: Dahmen Jari , Stufkens Sjoerd A.S. , Dalmau-Pastor Miki , Maas Mario , Kerkhoffs Gino M.M.J.
Published: December 2023

We describe an elite youth football player who developed lateral foot pain of previously unknown origin. A thorough patient history and physical examination as well as an in-depth presentation of radiographic findings on Computed tomography (CT) and Magnetic Resonance Imaging (MRI) scan were described. Through this combination, the puzzle was resolved and a rare peroneus longus tendinopathy due to bony spurs in the cuboid groove was diagnosed. A peroneus longus exploration, release and reduction of the cuboidal bone spurs was performed and intensive rehabilitation phase followed. The patient successfully returned to performance and set a career in professional football.
Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal cortex are organized at the scale of grid cell clusters
Authors: Huang Li-Wen , Garden Derek L.F. , McClure Christina , Nolan Matthew
Published: December 2023

Interactions between excitatory and inhibitory neurons are critical to computations in cortical circuits but their organization is difficult to assess with standard electrophysiological approaches. Within the medial entorhinal cortex, representation of location by grid and other spatial cells involves circuits in layer 2 in which excitatory stellate cells interact with each other via inhibitory parvalbumin expressing interneurons. Whether this connectivity is structured to support local circuit computations is unclear. Here, we introduce strategies to address the functional organization of excitatory-inhibitory interactions using crossed Cre- and Flp-driver lines to direct targeted presynaptic optogenetic activation and postsynaptic cell identification. We then use simultaneous patch-clamp recordings from postsynaptic neurons to assess their shared input from optically activated presynaptic populations. We find that extensive axonal projections support dense but incomplete connectivity between stellate cells and parvalbumin interneurons. Analysis of the spatial organization of synaptic interactions is consistent with local modules defined by excitatory-inhibitory connectivity. We suggest that dense, but specific, direct excitatory-inhibitory synaptic interactions may operate at the scale of grid cell clusters, while indirect interactions may coordinate activity at the scale of grid cell modules.
The non–muscle actinopathy–associated mutation E334Q in cytoskeletal γ–actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins
Authors: Greve Johannes N. , Marquardt Anja , Heiringhoff Robin , Reindl Theresia , Thiel Claudia , Di Donato Nataliya , Taft Manuel H. , Manstein Dietmar J.
Published: December 2023

Various heterozygous cytoskeletal γ–actin mutations have been shown to cause Baraitser–Winter cerebrofrontofacial syndrome, non–syndromic hearing loss, or isolated eye coloboma. Here, we report the biochemical characterization of human cytoskeletal γ–actin carrying mutation E334Q, a mutation that leads to a hitherto unspecified non–muscle actinopathy. Following expression, purification, and removal of linker and thymosin β4 tag sequences, the p.E334Q monomers show normal integration into linear and branched actin filaments. The mutation does not affect thermal stability, actin filament nucleation, elongation and turnover. Model building and normal mode analysis predict significant differences in the interaction of p.E334Q–filaments with myosin motors and members of the ADF/cofilin family of actin–binding proteins. Assays probing the interactions of p.E334Q–filaments with human class 2 and class 5 myosin motor constructs show significant reductions in sliding velocity and actin–affinity. E334Q differentially affects cofilin-mediated actin dynamics by increasing the rate of cofilin-mediated de novo nucleation of actin filaments and decreasing the efficiency of cofilin-mediated filament severing. Thus, it is likely that p.E334Q-mediated changes in myosin motor activity, as well as filament turnover contribute to the observed disease phenotype.