bluuebunny/crossref_metadata_2025 huggingface dataset:
Developing meaningful public involvement in HQIP’s data access processes and Data Access Request Group (DARG)
Authors: Snudden Claudia , Rezel Kim , Silove Yvonne , Biggs Tom , Davis Wendy , Markham Sarah , Molete Michael
Published: May 2024

BackgroundAs commissioners of the National Clinical Audit and Patient Outcomes Programme (NCAPOP), HQIP are custodians of data from across many areas of healthcare. The high quality and national coverage of circa 40 national audits and registries means datasets are sought after for many purposes.
IntroductionHQIP values placing patients and the public at the heart of our work. We wanted to work with members of our Service User Network (SUN) to research and design how to recruit and sustain public representation in our Data Access Request Group (DARG).
Our primary objective was to work in partnership with public members to co-design a sustainable model that implements meaningful public involvement within DARG.
Our intended outcomes were that HQIP is enabled to establish public membership in DARG, and that HQIP’s Data Access processes benefit from the added supportive challenge and assurance that public membership provides.
MethodsWe took the following steps to achieve our aims:

Recruited 3 public members to our project team from our SUN enabling us to have meaningful public involvement throughout.Public members contributed to discussions with other organisations with established public membership on their data access committees (IGARD, CPRD, Pioneer) and HDRUK, to gather knowledge on best practice in public engagement with data access processes.
Fortnightly team meetings to review progress, develop a model for public membership in DARG, and reflect on learnings throughout.
Invited our public members to observe a DARG meeting to better understand how our data access processes work, and followed this up with a Q&A session.
Our PPI lead actively supported public members throughout the project, enabling them to self-select how they wanted to contribute, and encouraging them to bring learning from other PPI work they have been involved with.

ResultsOur project outputs included:

A costed business case for establishing public membership within DARG: for HQIP reviewRecruitment resources: promotional materials, role description for public members, public involvement agreement, draft interview tasks and questions
DARG operating model: amended DARG Terms of Reference, Glossary of terms
Co-designed webpages: on HQIP’s Data Access Processes; inclusion of the Five Safes Framework
Supporting infographics: to visually display webpage content

ConclusionsThis project had the following impact and gave the following insights:

HQIP approval given for establishing public membership onto DARG
Improved public accessibility and understanding of HQIP’s data access processes
Clearer roles and responsibilities of DARG members
A platform within DARG to promote the patient and public voice
Learning for HQIP as it was the first-time public members were part of a project team – this brought diversity, new ideas, and challenge
Public project members more confident to challenge and question professionals in other settings
Bezpośrednie inwestycje zagraniczne w świetle teorii produkcji międzynarodowej
Authors: Tarasiński Leszek
Published: May 2024

W artykule omówiono wybrane aspekty teoretyczne zagadnienia bezpośrednich inwestycji zagranicznych. Praca stanowi pierwszy fragment czteroczęściowego cyklu poświęconego problematyce aspektów jw., ze szczególnym zwróceniem uwagi na niezwykle ciekawą poznawczo kwestię przyczyn podejmowania bezpośrednich inwestycji zagranicznych, przedstawioną w historycznej perspektywie badawczej tego jakże ważnego współcześnie zjawiska/procesu gospodarki światowej. W pierwszej - niniejszej – części cyklu będzie miała miejsce prezentacja teorii międzynarodowej produkcji J.H.Dunninga.
Analiza płynności finansowej na podstawie przedsiębiorstwa LPP w latach 2020-2022
Authors: Kopaniewska Izabela , Król Karolina , Ręba Sonia
Published: May 2024

W niniejszym artykule omówione zostały teoretyczne aspekty płynności finansowej, wraz ze wskazaniem różnicy między jej pomiarem dokonywanym w ujęciu statycznym oraz dynamicznym. Przedstawiono grupy najczęściej wykorzystywanych wskaźników, służących pomiarowi i ocenie płynności finansowej w przedsiębiorstwie. W części praktycznej oszacowano wartości wskaźników, na podstawie których dokonano oceny płynności finansowej spółki akcyjnej LPP, będącej jedną z największych firm odzieżowych w Polsce. Okres analizy obejmował lata 2020 – 2022. W artykule zostały wykorzystane metody analizy opisowej oraz statystyczna analiza danych finansowych. W opracowaniu dokonano analizy literatury przedmiotu z zakresu finansów i rachunkowości, obowiązujące akty prawne, wynikające z zakresu pracy, a także sprawozdania finansowe badanego podmiotu gospodarczego.
Kredyt w finansowaniu podmiotu gospodarczego
Authors: Bolek Julia
Published: May 2024

Artykuł przedstawia zakres i strukturę umowy kredytowej, która jest formalnym dokumentem regulującym relacje między bankiem a kredytobiorcą. Omawia kluczowe elementy umowy, takie jak kwota kredytu, cel jego przeznaczenia, zasady i terminy spłaty, oprocentowanie, zabezpieczenia, a także prawa i obowiązki obu stron. Prezentuje aspekt zdolności kredytowej, badając kryteria i procedury oceny zdolności kredytowej kredytobiorcy, zgodnie z wymaganiami banków. Artykuł analizuje zapotrzebowanie na kredyt w przedsiębiorstwach, przedstawiając dane dotyczące popytu na różne rodzaje kredytów. Opisane zostało znaczenie kredytu dla stabilności i wzrostu przedsiębiorstw w dynamicznym środowisku biznesowym, gdzie innowacje i rozwój są kluczowe. Podkreślono zmienność popytu na kredyt, która może być wynikiem różnych czynników, takich jak warunki rynkowe, polityka kredytowa banków, czy sytuacja makroekonomiczna.
Wskaźniki rentowności i ich analiza na przykładzie wybranego przedsiębiorstwa
Authors: Drabik Klaudia , Kozdra Kamila , Kuśmierczyk Karolina , Piechota Karina
Published: May 2024

W artykule omówiono podstawowe pojęcia dotyczące rentowności oraz przedstawiono rozważania dotyczące istoty tego pojęcia. W poszczególnych częściach artykułu przedstawiono teoretyczny aspekt rentowności, sposób obliczania określonych wskaźników rentowności oraz ukazano dane dotyczące przedsiębiorstwa. Dokonano również analizy rentowności przedsiębiorstwa Dino S.A. w latach 2020 – 2022. Celem artykułu jest próba wyjaśnienia pojęcia rentowności, a także przedstawienie poszczególnych wskaźników rentowności na przykładzie wybranego przedsiębiorstwa.
Metody i narzędzia motywowania w przedsiębiorstwach
Authors: Nieściór Julia
Published: May 2024

Artykuł dotyczy problematyki procesów motywacyjnych, a jej głównym celem jest zdobycie informacji na temat tego, czy przedsiębiorstwa wykorzystują procesy motywacyjne oraz czy są one efektywne. Artykuł dotyczy teoretycznego spojrzenia na istotę motywacji oraz zdefiniowania motywacji, jego narzędzi, metod, najważniejszych ponadczasowych teorii oraz czynników motywacyjnych i ich klasyfikacji, a także współczesnego spojrzenia na motywację. Kolejnym punktem jest wyznaczenie celu oraz przedmiotu badań, określenie problemu badawczego, hipotezy głównej oraz hipotez szczegółowych. Wyniki z przeprowadzonej analizy zgodnie z założonymi hipotezami pokazują, że przedsiębiorstwa nie wykorzystują w pełni procesów motywowania, a także, że odpowiednia motywacja ma wpływ na zachowania pracowników.
Carya illinoinensis y hongos del género Tuber en Argentina: un análisis bibliográfico
Authors: Quiroga Rocío , Morelli Gabriela A. , De Hagen Tomás , Saparrat Mario C. N.
Published: May 2024

Carya illinoinensis (Wangenh.) K. Koch, el “pecán”, es hoy en día un cultivo que está adquiriendo importancia en Argentina por su alto valor nutricional como alimento. Debido a esto, surge la necesidad de buscar alternativas sustentables, que promuevan su crecimiento y sanidad para lograr una mejor productividad y calidad del cultivo. Una alternativa puede ser la micorrización con hongos específicos y, principalmente las ectomicorrizas que se forman como resultado de la simbiosis del árbol con algunas especies de hongos, lo que otorga beneficios tanto a la planta como al hongo. Uno de los géneros de hongos ectomicorrícicos que tiene potencial como agente promotor del crecimiento de este cultivo forestal es Tuber. Este género se caracteriza por formar esporomas (fructificaciones, cuerpos fructíferos) hipogeos que se conocen con el nombre vulgar de “trufa”, los que hoy en día se comercializan en muchos países por su gran valor gastronómico. El objetivo de esta revisión bibliográfica fue indagar la información disponible sobre la interacción entre Carya illinoinensis y hongos del género Tuber y analizar la factibilidad de su uso para promover la producción de plantas de vivero. Este estudio sugiere un gran potencial de esta interacción para la producción en conjunto, ya que Carya illinoinensis ha sido reportada como hospedante de Tuber melanosporum Vittad. (Trufa Negra), Tuber brumale Vittad. (Trufa negra de otoño), Tuber borchii Vittad. (Trufa bianchetto), Tuber aestivum (Wulfen) Pers. (Trufa negra de verano) y Tuber lyonii Butters (Trufa del Pecán).
Chat GPT y Google: ¿Aliados o enemigos del profesorado para elaborar contenidos?
Authors: Guerrero Atenea , Villodres Cayetano , Jerez Encarna , Illescas Pilar
Published: May 2024

La popularización de Chat GPT como herramienta basada en el lenguaje de la Inteligencia Artificial (IA) convierte a este sistema en un recurso más dentro del aula.
El objetivo de esta investigación es determinar, a fecha de hoy, hasta qué punto puede resultar útil al profesorado para la elaboración deesquemas de contenidos y si mejora o no la experiencia ofrecida por un buscador tradicional como es el caso de Google.
También queremos saber si ambas herramientas ayudan a un docente, sin experiencia previa en un tema, a elaborar un contenido de calidad o si por el contrario el conocimiento del profesor sobre una temática concreta es determinante a la hora de gestionar los datos ofrecidos para obtener un resultado óptimo.
Gerador de trilhas de aprendizagem adaptativo e não supervisionado para plataforma de treinamento de profissionais
Authors: Pasti Rodrigo , Valerio Netto Antonio
Published: May 2024

Este artigo apresenta a criação de um algoritmo não supervisionado para geração de trilhas de aprendizagem com base no grau de dificuldade, na prioridade do conteúdo e no desempenho do profissional. Uma trilha de aprendizagem é um plano estruturado e organizado que descreve uma série de atividades educacionais ou de treinamento destinadas a ajudar os indivíduos a adquirir conhecimentos ou habilidades específicas. Normalmente, inclui uma progressão sequencial de tópicos e atividades, como materiais de leitura, aulas em vídeo e exercícios interativos. Todos destinados a atingir objetivos de aprendizagem. Uma das principais dificuldades encontradas em sua construção está associada à obtenção de trilhas personalizadas que respondam às necessidades específicas de cada profissional. Ao considerar que um instrutor deve criar trilhas para vários alunos, a tarefa torna-se inviável de ser executada, sendo necessária a utilização de algoritmos que auxiliem na geração automática dessas trilhas. O algoritmo desenvolvido foi incorporado na plataforma de qualificação e avaliação continuada da startup Xeduca e aplicada em um grupo de encarregadas de limpeza hospitalar com resultados positivos e que encorajam a continuação do projeto.
De la innovación como producto a la innovación como proceso: desafíos y estrategias para la transformación de la enseñanza en la universidad
Authors: Garcia Daiana , Domínguez María Alejandra , Stipcich María Silvia
Published: May 2024

La necesidad de propiciar procesos de innovación en las prácticas de enseñanza en el nivel universitario es indiscutible. Sin embargo, es imposible pensar que tal tarea recaiga completamente en los docentes, sino que indispensable el trabajo conjunto de diferentes actores. En esta oportunidad se comunica parte del proceso de transformación que tuvo lugar en las prácticas de enseñanza de Física en la universidad, como consecuencia de la colaboración entre profesores universitarios e investigadores en educación en ciencias, y se identifican  desafíos y estrategias que se asumen como potenciales para la innovación en el nivel.
Perspectivas acerca de las alfabetizaciones múltiples en la era de las inteligencias artificiales en la formación docente inicial de la provincia de Buenos Aires durante el período pospandemia
Authors: Conde Griselda Rosana , López Linda Angélica
Published: May 2024

El presente trabajo se enmarca en el Proyecto de investigación: Alfabetizaciones múltiples en la formación docente en los institutos de gestión estatal de la región IV de la Provincia de Buenos Aires en la pospandemia: Curriculum y propósitos para la enseñanza. Intenta visibilizar el lugar que adquieren las alfabetizaciones múltiples en la formación docente inicial. Esto implica configurar un escenario donde las tecnologías de la información y comunicación social (TICS) otorgan sentido y legitimidad en el ámbito de las políticas de formación docente. 
Así, interesa tomar como punto de referencia el anclaje conceptual que habilita a resignificar la mirada acerca los modos y posicionamientos que hacen posible pensar y encuadrar las prácticas de enseñanza en la formación docente inicial a partir del uso y acceso de la educación digital.
En este sentido, se pone énfasis en las estrategias que se implementan en un contexto específico y ligadas a la formación de docentes. Interesa poner en valor de qué modo se resignifican las mismas en pos de contribuir a la construcción de propuestas de integración de alfabetizaciones múltiples. 
De este modo, se explicitan las características que asumen las alfabetizaciones digitales como también los desafíos que se implican en las propuestas de enseñanza en contextos específicos de formación docente inicial en la provincia de Buenos Aires durante el período de pospandemia.
Reflexiones en torno al uso de IA en educación superior: dos casos comparados
Authors: Tramallino Carolina , Pairetti Ce´sar , Rodríguez Guillermo Jesús
Published: May 2024

El propósito del presente trabajo es sintetizar las primeras reflexiones en torno a un estudio comparativo del uso de Inteligencia Artificial como herramienta para el aprendizaje en dos asignaturas de carreras de nivel superior. Las propuestas pedagógicas se desarrollan  en las asignaturas curriculares Metodología de la Investigación Lingüística (Licenciatura en Traducción) y Dinámica de Fluidos Computacional (Ingeniería Mecánica), ambas dictadas en la Universidad Nacional de Rosario, Argentina. En dichos espacios, se buscó integrar el uso de la herramienta ChatGPT desde una perspectiva constructivista en torno a su empleo para la resolución de problemas vinculados a estas dos áreas disímiles de conocimientos. La metodología empleada es cualitativa y parte de la utilización de tres instrumentos; en primer lugar,  una encuesta destinada al grupo de estudiantes que releva la información diagnóstica inicial; en segundo lugar, la observación participante en clases y  por último, el análisis evaluativo de informes finales de los trabajos prácticos. Dichos resultados son puestos en tensión de modo comparativo con el marco teórico expuesto. Las conclusiones dan cuenta de posibles utilizaciones desde posicionamientos críticos que implican no sólo una determinada experticia previa de los estudiantes en torno a las temáticas disciplinares sino también, el despliegue de habilidades operativas vinculadas.
Sinopsis de la familia de los Protoxodontidae [Eoceno de Patagonia]
Authors: Mercerat Alcides
Published: May 2024

Paleontólogos eminentes, entre los cuales mencionaremos á Owen y Burmeister, han dado sabias descripciones de Mamíferos, que deben ser referidos á la familia de los Protoxodontidae.El señor Ameghino, autor de varias publicaciones, solo se ha encontrado en las condición de hacer un estudio sistemático de estos animales, habiendo aprovechado durante su permanencia en el Museo de La Plata, como sub.-director, de los restos bastante numerosos que de esta familia poseía entonces el establecimiento, algunos descu biertos por su Director, el señor Moreno, en las márgenes del río Santa Cruz, y los más traídos de ese mismo punto por don Carlos Ameghino, á quien este Museo, del que era empleado, envió á coleccionar objetos de historia natural.
O lugar das crianças de seis anos no ensino fundamental de nove anos
Authors: Mota Maria Renata Alonso
Published: May 2024

O objetivo deste texto é discutir como o Ensino Fundamental de nove anos está inserido em práticas de governamento da infância e, ainda, como essas práticas possibilitam outro lugar escolar para as crianças de seis anos, a partir da noção de governamentalidade desenvolvida por Michel Foucault. Para tal, foram utilizados alguns documentos que tratam da política de Ensino Fundamental de nove anos elaborados pelo Ministério da Educação e pela Secretaria de Educação do Estado do Rio Grande do Sul e matérias jornalísticas que foram publicadas sobre o assunto no período mais intenso da implementação dessa política (2005-2008). Neste texto, tematiza-se o lugar das crianças de seis anos no Ensino Fundamental, procurando mostrar que, com o deslocamento das crianças de seis anos para o Ensino Fundamental, ocorre um esmaecimento de fronteiras entre os dois níveis educacionais e que tal deslocamento pode estar provocando a produção de um sujeito aluno de seis anos.
Relação família-escola transmutada
Authors: Oliveira e Nogueira Marlice de
Published: May 2024

Este ensaio tem como objetivo principal refletir sobre a construção do indivíduo e dos processos de socialização, no contexto da relação entre famílias e escolas, tendo como pano de fundo as mutações sofridas pelas duas instâncias educativas na contemporaneidade. Primeiramente, a autora busca discutir, a partir de uma revisão de literatura sobre o tema, as mudanças conceituais da noção de socialização, confrontando a abordagem clássica de Durkheim e a “sociologia da experiência” de François Dubet. Em seguida, discute a constituição dos indivíduos contemporâneos, no interior das duas instâncias de socialização - família e escola -, analisando a tensão vivida pelos indivíduos, entre a necessidade de integração social e a construção das experiências individuais.
História, arquitetura e cidade: a viagem à Europa como estudo no início do Século XX
Authors: Cerasoli Josianne Francia
Published: May 2024

Neste artigo, são exploradas interpretações e repercussões das notas de viagem do arquiteto brasileiro Alexandre Albuquerque nos vários campos de atuação dos profissionais da cidadeno início do século XX. Premiado pela Escola Politécnica de São Paulo com uma estadia para estudos na Europa em 1906, o recém-diplomado Albuquerque elabora registros e reflexões sobre as transformações urbanas e as formas arquitetônicas observadas na visita a países como França, Bélgica, Áustria, Alemanha, Inglaterra e Itália, e, ao retornar ao Brasil,divulga sobre a viagem vários estudos com os quais dialoga por vários anos em sua atuação profissional e em outros escritos. Debatidos amplamente em São Paulo na época, estudos desse tipo foram entendidos como fundamentais para complementar a educação formal dos arquitetos e acabam interferindo, diretamente ou não, nos projetos de obras para edificações e em planos urbanísticos, nas atividades ligadas ao ensino formal de história da arquitetura e artes, e também especificamente nos apontamentos teóricos sobre arquitetura. Portanto, esta investigação tem como objetivo contribuir para a compreensão da importância das viagens de estudo e do papel da história da arquitetura europeia na escolha e na composiçãodos repertórios arquitetônicos no espaço urbano no início do século XX.PALAVRAS-CHAVE: Alexandre Albuquerque. Arquitetura (história). Viagens de formação.
Projeto urbano e inclusão social: Milão Pirelli la Bicocca
Authors: Eigenheer Daniela Maria , Somekh Nadia
Published: May 2024

Este trabalho objetiva analisar um caso de implementação de projetos urbanos em áreas industriais dentro de uma perspectiva de desenvolvimento local. Entende-se por projetos urbanos as iniciativas de renovação urbana concentradas em determinados setores da cidade que combinam agentes públicos e privados, cujos investimentos e intervenções seguem um plano urbanístico, podendo se apoiar no redesenho do espaço urbano e arquitetônico, em normas legais específicas e em novas articulações institucionais e formas de gestão, porém com ações que os diferenciem de meros empreendimentos imobiliários. O Projeto Pirelli La Bicocca é um caso exemplar de inclusão: coloca o espaço público de maneira central, preserva o patrimônio histórico e apresenta novas formas de trabalho e renda aliadas a uma participação democrática na sua formulação.
La protección solar y el riesgo de melanoma en la población deportista
Authors: Pastor Miriam , Redondo Juan , Martínez Rodrigo
Published: May 2024

El exceso de rayos ultravioleta puede causar efectos nocivos en la piel. Este hecho puede verse incrementado por diversos factores de riesgo como los hábitos de exposición solar, el fototipo y antecedentes de lesiones en la piel.Objetivo: conocer la existencia de problemas dermatológicos causados por la exposición prolongada de luz solar así como el grado de sensibilización acerca de los efectos nocivos de la inadecuada protección solar en la población dedicada a prácticas deportivas al aire libre.Metodología: Se ha utilizado un cuestionario sobre los hábitos de exposición solar dirigida a tres clubes deportivos de la ciudad de Plasencia. Las diferentes variables de estudio han sido analizadas a través del programa informático SPSS buscando la significación estadística.Resultados: La población estudiada, muestra un uso casi generalizado de algún tipo de protección solar (96,7%), pero utilizados de forma inadecuada. El dato más alarmante es que un elevado porcentaje de los participantes no reaplica la crema solar cada 2-3 horas (76%), por lo que ésta es eliminada mediante sudoración y fricción, y además, un 46% la utiliza únicamente en verano. En cuanto al grado de sensibilización, presentan actitudes positivas, dándole mayor relevancia a la salud frente a la belleza (67%).Conclusiones: Este estudio muestra que la práctica deportiva aumenta el riesgo de desarrollar lesiones en la piel inducidas por la radiación ultravioleta, esto se debe a la exposición solar prolongada, repetida y a la protección solar insuficiente. Es necesario promover nuevas campañas de sensibilización para incrementar la mejora de las conductas de protección solar en dicho grupo, cuya finalidad principal sea la autoexploración de la piel.
Effects of milk and fruit consumption on Crohn's disease: a systematic review
Authors: Mangas-Borrego María I.
Published: May 2024

Introduction: There are currently many studies that discuss possible relationships among thediet, the etiology of Crohn's disease and the possible improvement or worsening of its symptoms. Most ofthem are based on surveys that describe the dietary patterns adopted by these patients. Objectives: Thepresent review will address quantitative studies comparing the consumption of certain foods (milk andfruits) by subjects diagnosed with Crohn's disease and healthy subjects. On the other hand, it will alsoaddress studies of patients who exclude these foods from their diets because they associate them withworsening symptoms of the disease. Methodology: This systematic review was elaborated following the PRISMA guidelines. Six studies that analyze the selected subject matter were selected. Results: The twofoods selected for study are very often present in articles that relate diet and Crohn's disease, and both areconsidered by patients to be influential in the evolution of their pathology. Conclusions: Each studypresents different results; thus, to date, there is no consensus on the best diet to follow in inflammatorybowel disease. Of course, it has not been sufficiently demonstrated that the consumption of certain foodscauses or worsens the development of this disease. Therefore, further investigations are necessary.
Optimal control of maximum torque current ratio for synchronous reluctance motor based on virtual signal injection algorithm
Authors: Cui Jinghua
Published: May 2024

This study focuses on the maximum torque current ratio control of synchronous reluctance motors and proposes an optimized control method for the maximum torque current ratio of synchronous reluctance motors based on virtual signal injection. Firstly, the research on the maximum torque current ratio control of synchronous reluctance motors based on the virtual signal injection method is conducted, and the existing virtual unipolar square wave signal injection method is analyzed and studied. Secondly, a non-parametric maximum torque current ratio control strategy based on a synchronous reluctance motor combined with the virtual signal injection method is proposed. This strategy does not involve complex parameter calculations, and the control accuracy is not limited by the accuracy of the parameters in the model. The experimental results showed that under the control of virtual bipolar and unipolar square wave signal injection methods, the load torque was converted from 2 Nm to 6 Nm at t = 2:5 s, and there was a significant change in the current amplitude and waveform of the current vector. Under the control of the bipolar injection method, the current amplitude waveform of the motor was lower than that of the unipolar waveform, and the current was smaller. After the load suddenly changed, it could enter a stable state faster. After the load changed at t = 2:5 s, the phase angle of the current vector was quickly adjusted and stabilized under the control of the bipolar signal. The designed method has a good optimization effect compared to the traditional virtual signal injection method, and can achieve high-performance maximum torque current ratio optimization control on synchronous reluctance motors.
Effectiveness analysis of anti-galloping of spacer for catenary additional wires in strong wind section of high-speed railways
Authors: Zhang Youpeng , Zhang Yahui , Zhao Shanpeng , Feng Qiang , Yao Xiaotong , Yang Ni
Published: May 2024

To effectively suppress the violent galloping of the catenary additional wires in the strong wind section of high-speed railways, the anti-galloping effectiveness and anti-galloping mechanism of the spacer installed on the catenary additional wires are studied. Firstly, the finite element model of the additional wires of the catenary before and after the installation of the spacer is established. Secondly, the random wind field at the additional wires is simulated by the harmonic synthesis method (WAWS). Finally, the galloping response of the additional wires before and after the installation of the spacer is studied by using the finite element software. The results show that the installation of a single spacer at the midpoint of the span can reduce the vertical amplitude of the AF (Additional Feeder) and the PW (Protection Wire) by more than 39.80% and 41.51%, respectively, and the lateral amplitude decreases by more than 16.55% and 38.30%, respectively. The tension of the AF is greatly reduced, while the tension of the PW is slightly increased, so that the galloping of the AF and the PW tends to be synchronized. With the increase in the number of spacers installed, the anti-galloping effect continues to increase. At the same time, the anti-galloping mechanism of the spacer rod to suppress the vibration of the additional wires through the traction effect is clarified, and the effectiveness of the spacer rod in the anti-galloping of the additional wires of the catenary is proved.
Antimicrobial Susceptibility in Clinical Mastitis Cases on Simmental Farms in the Mačva Region (Serbia)
Authors: Ninković Milan , Žutić Jadranka , Pavlović Marija , Jezdimirović Nemanja , Radanović Oliver , Nikolić Marko , Zdravković Nemanja
Published: May 2024

The battle against mastitis remains an enduring challenge in contemporary animal farming. This paper presents the frequency of bacterial pathogens isolated from milk samples collected on 3 farms with a previous history of clinical mastitis in the Mačva region during the year 2022. A total of 77 Simmental cows were enrolled in the study, ranging from the first to sixth lactation and managed in a tie-stall system. The results obtained indicate that the frequency of clinical mastitis in the animals considered was 16.9%. Of a total of 13 pathogenic isolates with clinically present mastitis, Staphylococcus aureus was recorded in 5 (38.4%), Streptococcus uberis in 3 (23.1%), Escherichia coli in 2 (15.4%), Klebsiella pneumoniae in 2 (15.4%), and Streptococcus dysagalactiae in 1 (7.7%). Notably, the largest number of clinical mastitis cases (namely 8, or 61.5%) was recorded during the winter period. Both cases of mastitis caused by K. pneumoniae were detected in the summer, the occurrence of which was implicated in changes in the bedding straw. According to the stage of lactation, the highest frequency of mastitis was found in the early stage of lactation totaling 8 cases (61.5%), followed by 4 (30.8%) in the middle phase of lactation, and only 1 (7.7%) in the late stage of lactation. The causative agents of the Streptococcus genus showed susceptibility to β lactamates in all the cases, whereas all of the E. coli and K. pneumoniae isolates were found resistant to ampicillin, amoxicillin with clavulanic acid.
Advances in the application of biosynthesized carbon dots as fluorescent probes for bioimaging
Authors: Li Xuechan , He Jiefang
Published: May 2024

Carbon dots (CDs) are emerging as versatile fluorescent nanoprobes for bioimaging applications due to advantages like tunable emissions, excellent biocompatibility, facile surface functionalization, and ease of synthesis. This review summarizes recent advances in applying biosynthesized CDs for sensitive bioimaging. CDs derived from sustainable biomass sources through green techniques like hydrothermal and microwave synthesis demonstrate bright, excitation-tunable photoluminescence spanning visible to near-infrared spectra. Careful control of synthesis parameters and surface passivation strategies enhance quantum yields above 50% comparable to toxic semiconductor dots. Conjugation with polymers, peptides, and recognition elements like antibodies impart solubility and selectivity towards cancer cells and biomarkers. In vitro validation in standard lines shows targeted organelle imaging abilities. In vivo administration reveals renal clearance pharmacokinetics with preferential tumor accumulation via enhanced permeability effects. Average tumor growth inhibition around 50-80% was achieved in mouse xenografts using CDs-drug formulations through combined therapeutic effects of chemotherapy and photothermal ablation under imaging guidance. However, concerns regarding toxicity from chronic exposures, large-scale reproducible manufacturing, and multimodal imaging capabilities need redressal prior to further clinical translation.
The Legal Analysis as an Organizational Factor for the Efficient and Effective Management of Agribusiness
Authors: Rocha Júnior Paulo Roberto de Souza , Rosa Andréia Alves , Santos Wallace Fábio Rodrigues , Silva Douglas Pereira , Moreira Ivaldo de Sousa
Published: May 2024

Objective: This study aims to analyze the lack of legal considerations in project management in agribusiness, highlighting the scarcity of mentions of these factors in academic literature. We seek to understand the importance of integrating legal analysis for a more comprehensive and effective approach to project management in this specific sector.
 
Theoretical Framework: Project management in agribusiness often overlooks legal factors, despite their relevance. Existing literature typically focuses on aspects such as scope, time, costs, quality, human resources, communications, risks, acquisitions, integration, stakeholders, and culture. However, the lack of legal considerations is concerning, given the complexity of the agribusiness context.
 
Method: Twenty-one articles on project management in agribusiness were examined to observe if they mentioned legal factors. The analysis consisted of verifying the presence of explicit or implicit mentions of these aspects in the selected articles.
 
Results and Discussion: The analysis revealed that only 2 out of 21 articles addressed legal factors, highlighting a significant gap in the literature on the topic. The lack of integration of legal analysis can have negative impacts on projects, affecting costs and feasibility. However, the incorporation of these aspects can mitigate legal and financial risks, improve corporate reputation, and promote the long-term sustainability of the agricultural sector.
 
Research Implications: Underestimating legal factors in agricultural project management directly contradicts the principles of the Brazilian Federal Constitution. Based on the results obtained, the need for a more comprehensive approach that integrates legal considerations for effective project management in agribusiness becomes evident.
 
Originality/Value: This study contributes to filling a gap in the literature by highlighting the scarcity of legal considerations in project management in agribusiness. Additionally, it underscores the importance of integrating these aspects for a more effective and sustainable management approach in this specific sector.
Study on Temple Waste Management and its Potential for Reducing Carbon Emission
Authors: Wiratama I Gusti Ngurah Made , Wijaya I Made Wahyu
Published: May 2024

Objective: This study aims to investigate waste management practices at temple sites in Bali, Indonesia, with the overarching goal of reducing carbon emissions and promoting environmental sustainability amidst increasing waste generation and frequent ceremonial events.
 
Theoretical Framework: The study relies on key theoretical concepts from environmental science, waste management, tourism studies, and sustainability. These include population dynamics and waste generation, principles of sustainable waste management, and the intersection of cultural tourism with environmental conservation.
 
Method: This study employs a comprehensive methodology that involves the analysis of waste composition and generation using the Indonesian National Standard (SNI) 19-3964-1994. Additionally, we collected data through interviews and expenditure assessments to evaluate existing waste management practices and understand visitor behaviours.
 
Results and Discussion: Analysis revealed significant quantities of waste generated at temple sites, with Watu Klotok Temple emerging as the largest contributor, producing 449.87 kg of waste. Other significant contributors included Tanah Kilap Tampel, Saraswati Temple, Mutering Jagat Sidakarya Temple, Jagatnatha Temple, and Pucak Mangu Temple. Predominantly, organic waste accounted for 84.33% of total waste, while plastic and food waste constituted 4.08% and 11.59%, respectively. We observed a strong positive correlation between visitor numbers and waste generation, underscoring the urgent need for sustainable waste management practices to mitigate environmental impact and reduce carbon emissions.
 
Research Implications: The results of this study have both practical and theoretical implications for waste management strategies and environmental conservation efforts in Bali's cultural landscape. This research's recommendations, such as promoting locally sourced fruits and implementing waste segregation programmes, have broader implications for waste management policies and practices in similar contexts.
 
Originality/Value: This research contributes to the existing literature by providing empirical evidence on waste management practices at temple sites in Bali and quantifying the potential for carbon emissions reduction. This study's interdisciplinary approach highlights its relevance and value in tackling environmental issues in culturally significant regions and advancing sustainable development practices.
Prevalensi Ektoparasit Pada Kucing di Klinik Hewan Winadivet Malang
Authors: Siagian Tetty Barunawati , Hadi Ikfa Sulkhan , Syafitri Winda
Published: May 2024

AbstractCats are domesticated animals whose existence is very close to humans. Maintenance of the wrong cat will cause the risk of zoonotic diseases. to humans caused by ectoparasites. Ectoparasites in cats are fleas, mites, and fleas. Information regarding the prevalence of ectoparsite infestation in cats can be used as a preventive measure. The purpose of this final report is to explain the prevalence of ectoparasites in cats at the Winadivet Animal Clinic in Malang. Prevalence sample examination was carried out on 156 cats divided into 7 breeds, namely Domestic, Persian, Bengal, British Short Hair, Peaknose, Anggora, Himalayan who came to the clinic during April 2021. Examination was carried out macroscopically and microscopically, microscopic method using native method. The results of the examination found 45 cats that were positively infected with ectoparasites, namely the Ctenocephalides felis flea, Felicola subrostatus fleas, Otodectes cynotis mites, and Sarcoptes scabei. The prevalence of infestation obtained was 28.8%. The highest prevalence of ectoparasites in purebred cats is in domestic cats with a prevalence value of Ctenocephalides felis 12.7%, Felicola Subrostatus 5.1%, Otodectes cynotis 3.2%, Sarcoptes scabei 0.6%. Factors that influence the high prevalence are environment, temperature, humidity, maintenance, and direct contact from infected animals.
Ekspolarasi dan Karakterisasi Morfologi Jamur Makroskopis di Kawasan Hutan Adat Bukit Selebu, Kabupaten Merangin beserta Klasifikasi Potensinya Menggunakan K-Nearest Neighbors
Authors: Zuhri Rozana , Satria Deni
Published: May 2024

Fungi are one of Indonesia's potential natural resources which contain various benefits for human life. The existence of macroscopic fungi is not yet well known so that little information about the types and their benefits is known to local people. In fact, information about species of fungi is very important because fungi have economic value and are producers for the food and pharmaceutical sectors. Populations of macroscopic fungi can disappear due to climate change and environmental factors, therefore, it is necessary to collect data on the species of macroscopic fungi. One way to detect the species of fungus is to classify it based on the morphological characteristics of the fungus with K-Nearest Neighbor. The aim of this research is to explore and identify the morphological characteristics of fungi using K-Nearest Neighbor as a classifier found in the Bukit Selebu traditional forest area, Merangin Regency. It is hoped that the results of this research can be the first step in efforts to utilize fungi through further research. This research was carried out in the Bukit Selebu traditional forest area, Merangin Regency and identification continued at the Biology Laboratory of Merangin University. Then the data on the species of fungi found were analyzed using k-Nearest Neighbors (kNN). The results of this research are that there are 27 species of fungi found in the Bukit Selebu traditional forest area, Merangin Regency, consisting of 3 species of Ascomycota divisions and 24 species of Basidiomycota divisions. The K-Nearest Neighbor method is very good in classifying fungi through the extraction of morphological characteristics with the highest accuracy reaching 93%.
Pengaruh Benzil Aminopurin (BAP) terhadap Induksi Tunas dari Nodus anggrek Dendrobium mussauense
Authors: Media Media , Noli Zozy Aneloi
Published: May 2024

Dendrobium mussauense has attractive flowers and potential as a parent of a hybrid orchid. The color of this species is cream with violaceous purple venations on the labellum. D. mussauense is an orchid species listed as vulnerable in IUCN. This species is not located in protected areas nor known to be conserved ex-situ. Clonal propagation is an important biotechnological tool for the conservation of orchids. Thin cell layer (TCL) is a micropropagation method using thin-sized explants that facilitate the diffusion of nutrients to tissues. This study examined induction shoot through two explant cutting techniques, namely TCL and non-TCL explant, at various concentrations of BAP. The non-TCL explant was more effective than the TCL explant in inducing the shoot of D. mussauense. The half-strength Murashige and Skoog (MS) medium supplemented with 0.9 mg.L-1 BAP was a suitable concentration to induce the shoot of D. mussauense through non-TCL explant. The average shoot length was 1,8 cm, and the average number of shoots was 5/explant.
Music by André Previn for the Film by Richard Brooks “Elmer Gantry” (1960) as a Semantic Factor
Authors: Дубова А.Ю. , Окунева Е.Г.
Published: May 2024

Объектом исследования в статье выступает музыка американского композитора А. Превена к фильму Р. Брукса «Элмер Гентри» (1960) по мотивам романа С. Льюиса. Особенностью саундтрека является его стилистическая многокомпонентность. Три стилевых пласта — духовные песнопения, джаз и авторская (академическая) музыка —способствуют выявлению смысловых подтекстов картины: борьбы между чувством и долгом у Шэрон Фолконер, борьбы между местью и любовью у Лулу, лицемерия Гентри. Двойственность, характеризующая всех ключевых героев фильма, находит отражение в стилистических модуляциях внутри одного саундтрека и в преобразованиях выразительного характера лейттем, закрепленных за женскими персонажами. Важную роль приобретает и прием «смыслопорождения через жанр».

The object of the research in the article is the music of the American composer A. Previn for the film by R. Brooks “Elmer Gantry” (1960) based on the novel by S. Lewis. A special feature of the soundtrack is its stylistic multicomponence. Three stylistic layers — Christian hymn, jazz and author’s (academic) music — contribute to the identification of the semantic subtexts of the film: the struggle between feeling and duty in Sharon Falconer, the struggle between revenge and love in Lulu, and the hypocrisy of Gantry. The duality that characterizes all the key characters of the film is reflected in the stylistic modulations within one soundtrack and in the transformations of the expressive character of the leitmotifs assigned to the female characters. The technique of “meaning generation through genre” also acquires an important role.
Assessment of molecular dynamics time series descriptors in protein-ligand affinity prediction.
Authors: Poziemski Jakub , Yurkevych Artur , Siedlecki Pawel
Published: May 2024

The advancement of computational methods in drug discovery, particularly through the use of machine learning (ML) and deep learning (DL), has significantly enhanced the precision of binding affinity predictions. Despite progress in computer-aided drug discovery (CADD) accurate prediction of binding affinity remains a challenge due to the complex, non-linear character of molecular interactions. Generalizability continues to limit these models, with performance discrepancies noted between training datasets and external test conditions. This study explores the integration of molecular dynamics (MD) simulations with ML to assess its predictive performance and limitations. In particular MD simulations offer a dynamic perspective by depicting the temporal interactions within protein-ligand complexes, potentially bringing additional information for affinity and specificity estimates. By generating and analyzing over 800 unique protein-ligand MD simulations, we evaluate the utility of MD-derived descriptors based on time series in enhancing predictive accuracies. The findings suggest specific and generalizable features derived from MD data and propose approaches to augment the current in silico affinity prediction methods.
Characterization of Changes in Carbonaceous Support During Synthesis by Means of Coefficient Alfa
Authors: Arnal Pablo
Published: May 2024

Background: In the synthesis of materials composed of nano or microparticles supported on charcoal (or carbon), the carbonaceous support is often considered to be an inert material that acts as a physical support. However, the support may undergo significant chemical changes during synthesis that could influence the behavior of the synthesized material. This work proposes to use the coefficient alfa as an indicator of the changes that the support undergoes in a synthesis via impregnation. Methods: After developing a mathematical equation to obtain the value of the coefficient alfa experimentally, we calculated the value of the coefficient alfa in the synthesis of a composite material obtained by wet impregnation. In addition, we calculated the value of the coefficient alfa in a negative control group. Results: The coefficient alfa calculated for the material obtained by wet impregnation indicates that the carbonaceous support experienced significant mass loss during synthesis (p < 0.0001). In the case of the negative control group, the coefficient alfa shows that significant mass loss (p < 0.0001) also occurs when the support is treated with the solvent (instead of the particulate precursor solution). The mass loss of the carbonaceous support is significantly higher (p < 0.0013) during the synthesis of the composite material than during the synthesis of the negative control group. Conclusion: The coefficient alfa is an indicator that allows one to verify the mass changes that the carbonaceous support undergoes during the synthesis of particulate material supported on carbon. Since a mass change implies a chemical modification of the support, these chemical changes should be taken into account when explaining the behavior of composite materials.
Direct excitation of carbonyl cyclopropanes: From divergent photo-isomerization and annulation to unified reductive C-C cleavage
Authors: Nguyen Tin V. T. , Bossonnet André , Brownsey Duncan K. , Wodrich Matthew D. , Waser Jerome
Published: May 2024

We report herein our studies on the direct photoactivation of carbonyl cyclopropanes to give biradical intermediates, leading to selective cleavage of the more substituted carbon-carbon bond. Depending on the substrate structure, extended alkenes were isolated or directly reacted in a photo-Nazarov process to give bicyclic products. Based on these results, a unified reductive ring-opening reaction was developed by using diphenyl disulfide as a HAT reagent. By performing a sequential cyclopropanation/selective ring opening reaction, we achieved a CH2 insertion into the alpha,beta- bond of both acyclic and cyclic unsaturated carbonyl compounds. Our protocol therefore provides a further tool for framework-editing of carbocycles, complementing the recent progress in "skeletal editing" strategies.
A multiomic characterization of the leukemia cell line REH using short- and long-read sequencing
Authors: Lysenkova Wiklander Mariya , Arvidsson Gustav , Bunikis Ignas , Lundmark Anders , Raine Amanda , Marincevic-Zuniga Yanara , Gezelius Henrik , Bremer Anna , Feuk Lars , Ameur Adam , Nordlund Jessica
Published: May 2024

The B-cell acute lymphoblastic leukemia (ALL) cell line REH, with the t(12;21)ETV6::RUNX1translocation, is known to have a complex karyotype defined by a series of large-scale chromosomal rearrangements. Taken from a 15-yr-old at relapse, the cell line offers a practical model for the study of pediatric B-ALL. In recent years, short- and long-read DNA and RNA sequencing have emerged as a complement to karyotyping techniques in the resolution of structural variants in an oncological context. Here, we explore the integration of long-read PacBio and Oxford Nanopore whole-genome sequencing, IsoSeq RNA sequencing, and short-read Illumina sequencing to create a detailed genomic and transcriptomic characterization of the REH cell line. Whole-genome sequencing clarified the molecular traits of disrupted ALL-associated genes includingCDKN2A,PAX5,BTG1,VPREB1, andTBL1XR1, as well as the glucocorticoid receptorNR3C1. Meanwhile, transcriptome sequencing identified seven fusion genes within the genomic breakpoints. Together, our extensive whole-genome investigation makes high-quality open-source data available to the leukemia genomics community.