bluuebunny/crossref_metadata_2025 huggingface dataset:
40 ANOS DE MACABÉA, A MENOR MULHER DO MUNDO
Authors: Castello Branco Lucia
Published: April 2018

Tomando como referência a edição comemorativa dos 40 anos de A hora da estrela (Rocco, 2017), o artigo propõe uma leitura desse romance de Clarice Lispector, em articulação com um de seus contos, “A menor mulher do mundo”, tendo como base as construções lacanianas acerca do “feminino” e a figura do “feminino de ninguém”, proposta por Maria Gabriela Llansol, em sua obra.
PRÁTICAS DE LEITURA EM SALA DE AULA: UMA SEQUÊNCIA DIDÁTICA PARA O LETRAMENTO LITERÁRIO
Authors: Carvalho Isaías Francisco de , Novaes João Valci Dos Santos , Rodrigues Rosilma Silva
Published: April 2018

O trabalho discute questões referentes à leitura em sala de aula, enfatizando-a como processo fundamental para o desenvolvimento da expressão, comunicação e interação social dos educandos. Compreendendo a prática de leitura na escola como uma atividade que demanda planejamento e elaboração de objetivos, tecemos argumentos em favor do uso das estratégias para favorecer a compreensão leitora e interpretativa, em situações contextualizadas. Para tanto, sugerimos uma proposta de ensino elaborada a partir do modelo de sequência didática delineada por Dolz, Noverraz e Schneuwly (2004). Utilizamos a crônica “O lixo”, de Luís Fernando Veríssimo, como objeto literário. Para fundamentar esta proposta, nos respaldamos, entre outros, nos estudos de Oliveira (2010), Solé (1998), Cosson (2014) e Colomer e Camps (2002), os quais apresentam pertinentes contribuições sobre práticas de leitura e compreensão leitora no espaço escolar, assim como reflexões acerca da formação do leitor de textos literários.
PESQUISA NA WEB: ANÁLISE DOS CAMINHOS INVESTIGATIVOS COM MÚLTIPLOS TEXTOS
Authors: Souza Juliana Machado A. , Santos Marcos Celírio dos , Garcia Roberta
Published: April 2018

Com o advento da tecnologia, a sociedade que se configura exige do sujeito letrado conhecimentos mais complexos para enfrentar novas situações, em diversos campos da atuação humana. No âmbito escolar, apesar de contarem com diversos aparatos tecnológicos, o que se tem visto é uma educação com base na transferência de informações, suscitando um trabalho ainda nos moldes tradicionais. Por esse motivo, é viável dizer que o ensino com as tecnologias deve ser ressignificado. Nesse sentido, é crucial que o professor se aproprie de saberes que possibilitem a (re)estruturação em sua prática pedagógica. Sendo assim, pretende-se aqui apresentar um trabalho investigativo, decorrente de pesquisas na Web, envolvendo múltiplos textos, com alunos da EJA, além de análises dos caminhos percorridos pelos aprendizes, ao longo do processo. Intenta-se argumentar sobre a importância da mediação do professor e de um trabalho de ensino sistematizado, em contraposição a um trabalho espontâneo e livre.
MITO E POESIA, ESPAÇOS INTERCAMBIÁVEIS
Authors: Cavalcanti Luciano Dias
Published: April 2018

A literatura está estreitamente associada à dimensão mítica porque uma das fortes marcas da natureza literária (como a do mito) é promover o encontro do indivíduo com a memória profunda (anamnese) da cultura. A literatura – e mais especificamente a linguagem poética – quer reviver a experiência primeira da nomeação das coisas do mundo como nos primórdios. Esta experiência é essencialmente poética, inaugural situação que coloca em campos análogos o mito e a poesia.
Effect of the distribution of states in amorphous In-Ga-Zn-O layers on the conduction mechanism of thin film transistors on its base
Authors: Estrada Magali , Hernandez-Barrios Yoanlys , Moldovan Oana , Cerdeira Antonio , Lime Francois , Pavanello Marcelo , Iñiguez Benjamin
Published: April 2018

Amorphous In-Ga-Zn-O Thin Film Transistors (a-IGZO TFTs) have proven to be an
excellent approach for flat panel display drivers using organic light
emitting diodes, due to their high mobility and stability compared to other
types of TFTs. These characteristics are related to the specifics of the
metal-oxygen-metal bonds, which give raise to spatially distributed s
orbitals that can overlap between them. The magnitude of the overlap between
s orbitals seems to be little sensitive to the presence of the distorted
bonds, allowing high values of mobility, even in devices fabricated at room
temperature. In this paper, we show the effect of the distribution of states
in the a-IGZO layer on the main conduction mechanism of the a-IGZO TFTs,
analyzing the behavior with temperature of the drain current.
Cost-effective sensors and sensor nodes for monitoring environmental parameters
Authors: Vasiljevic Dragana , Zlebic Cedo , Stojanovic Goran , Simic Mitar , Manjakkal Libu , Stamenkovic Zoran
Published: April 2018

This paper reviews the design and characterization of humidity and pH sensors
manufactured in the printed circuit board (PCB), ink-jet, and screen
printing technologies. The first one (PCB technology) provides robust
sensors with PET film which can be exposed to harsh environment. The second
(ink-jet technology) can manufacture sensors on flexible substrates (foils
and papers). The third (screen printing technology) has been used to
implement a thick-film sensor. In addition to this, a multi-sensor
cloud-based electronic system with autonomous power supply (solar panels)
for air and water quality monitoring has been described. Finally, a flexible
and modular hardware platform for remote and reliable sensing of
environmental parameters has been presented.
Comparative evaluation of quasi-delay-insensitive asynchronous adders corresponding to return-to-zero and return-to-one handshaking
Authors: Balasubramanian Padmanabhan
Published: April 2018

This article makes a comparative evaluation of quasi-delay-insensitive (QDI)
asynchronous adders, realized using the delay-insensitive dual-rail code,
which adhere to 4-phase return-to-zero (RTZ) and 4-phase return-to-one (RTO)
handshake protocols. The QDI adders realized correspond to the following
adder architectures: i) ripple carry adder, ii) carry lookahead adder, and
iii) carry select adder. The QDI adders correspond to three different timing
regimes viz. strong-indication, weak-indication, and early output. They are
physically implemented using a 32/28nm CMOS process. The comparative
evaluation shows that, overall, QDI adders which correspond to the 4-phase
RTO handshake protocol are better than the QDI adder counterparts which
correspond to the 4-phase RTZ handshake protocol in terms of latency, area,
and average power dissipation.
Memory chips and units radiation tolerance dependence on supply voltage during irradiation and test
Authors: Petrov Andrey , Nikiforov Alexander , Boruzdina Anna , Ulanova Anastasia , Yanenko Andrey
Published: April 2018

In this work we investigate the influence of various memory chips supply
voltage on their sensitivity to the radiation environment. The main physical
mechanisms responsible for radiation-induced degradation at nominal,
increased, and decreased supply voltage values are discussed. It is
demonstrated that, depending on supply voltage value during irradiation and
subsequent testing, device's tolerance to data corruption effects in memory
circuits, single event latch-up (SEL) and hard errors induced by ionizing
radiation can vary significantly. We also give some recommendations to
perform radiation tests.
Trade-off between multiple criteria in smart home control system design
Authors: Janjic Aleksandar , Velimirovic Lazar , Stankovic Miomir , Djordjevic Vladimir
Published: April 2018

The successful automation of a smart home relies on the ability of the smart
home control system to organize, process, and analyze different sources of
information, according to several criteria. Because of variety of key design
criteria that every smart home of the future should meet, the main challenge
is the trade-off between them in uncertain environment. In this paper, a
problem of smart home design has been solved using the methodology based on
multiplicative form of multi-attribute utility theory. Aggregated functions
describing different smart home alternatives are compared using stochastic
dominance principle. The aggregation of different criteria has been
performed through their numerical convolution, unlike usual approach of
pairwise comparison, allowing only the additive form of aggregation of
individual criteria. The methodology is illustrated on the smart home
controller parameter setting.
Retraction: Mohammad Maghsoudloo, Hamid R. Zarandi: Parallel execution tracing: An alternative solution to exploit under-utilized resources in multi-core architectures for control-flow checking. Facta universitatis, series: Electronics and Energetics (FU Elec Energ), vol. 29, no 2, june 2016, pp. 243-260. DOI: 10.2298/FUEE1602243M
Authors: Editorial E
Published: April 2018

The article: PARALLEL EXECUTION TRACING: AN ALTERNATIVE SOLUTION TO EXPLOIT
UNDER-UTILIZED RESOURCES IN MULTI-CORE ARCHITECTURES FOR CONTROL-FLOW
CHECKING. Mohammad Maghsoudloo, Hamid R. Zarandi. Facta Universitatis,
Series: Electronics and Energetics, Vol. 29, No 2, June 2016, pp. 243-260,
DOI: 10.2298/FUEE1602243M, repeats 62% data already published in: An
efficient adaptive software-implemented technique to detect control-flow
errors in multi-core architectures. Mohammad Maghsoudloo, Hamid R. Zarandi,
Navid Khoshavi. Microelectronics Reliability, Vol. 52, Issue 11, November
2012, pp. 2812-2828, DOI: doi.org/10.1016/j.microrel.2012.03.033 without any
referencing.

 Link to the retracted article <a
href="http://dx.doi.org/10.2298/FUEE1602243M ">10.2298/FUEE1602243M
Long-term skeletal effects of high-pull headgear followed by fixed appliances for the treatment of Class II malocclusions
Authors: Bilbo E. Erin , Marshall Steven D. , Southard Karin A. , Allareddy Verrasathpurush , Holton Nathan , Thames Allyn M. , Otsby Marlene S. , Southard Thomas E.
Published: April 2018

Objectives:

The long-term skeletal effects of Class II treatment in growing individuals using high-pull facebow headgear and fixed edgewise appliances have not been reported. The purpose of this study was to evaluate the long-term skeletal effects of treatment using high-pull headgear followed by fixed orthodontic appliances compared to an untreated control group.

Materials and Methods:

Changes in anteroposterior and vertical cephalometric measurements of 42 Class II subjects (n = 21, mean age = 10.7 years) before treatment, after headgear correction to Class I molar relationship, after treatment with fixed appliances, and after long-term retention (mean 4.1 years), were compared to similar changes in a matched control group (n = 21, mean age = 10.9 years) by multivariable linear regression models.

Results:

Compared to control, the study group displayed significant long-term horizontal restriction of A-point (SNA = −1.925°, P < .0001; FH-NA = −3.042°, P < .0001; linear measurement A-point to Vertical Reference = −3.859 mm, P < .0001) and reduction of the ANB angle (−1.767°, P < .0001), with no effect on mandibular horizontal growth or maxillary and mandibular vertical skeletal changes. A-point horizontal restriction and forward mandibular horizontal growth accompanied the study group correction to Class I molar, and these changes were stable long term.

Conclusions:

One phase treatment for Class II malocclusion with high-pull headgear followed by fixed orthodontic appliances resulted in correction to Class I molar through restriction of horizontal maxillary growth with continued horizontal mandibular growth and vertical skeletal changes unaffected. The anteroposterior molar correction and skeletal effects of this treatment were stable long term.
Growth hormone receptor gene is related to root length and tooth length in human teeth
Authors: Hikita Yu , Yamaguchi Tetsutaro , Tomita Daisuke , Adel Mohamed , Nakawaki Takatoshi , Katayama Koshu , Maki Koutaro , Kimura Ryosuke
Published: April 2018

Objectives:

To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants in a healthy Japanese population.

Materials and Methods:

The subjects consisted of 193 Japanese adults (69 men, 124 women), aged 13 to 56 years. Genomic DNA was extracted from saliva and genotyped GHR rs6184 and rs6180 variants using the Taqman genotyping. Computed tomography (CT) images were acquired using a dental cone-beam CT scanner and reconstructed using open-source OsiriX medical image processing software. The maxillary (upper; U) and mandibular (lower, L) central incisors (1), lateral incisors (2), canines (3), first premolars (4), second premolars (5), first molars (6), and second premolars (7) were evaluated. Teeth were assessed for crown height (CH), root length (RL), overall tooth length (C+R), and crown to root ratio (C/R). The relationships between GHR variants and CH, RL, C+R, and C/R were statistically examined.

Results:

The GHR variant rs6184 was associated with the root lengths and tooth length for the upper and lower lateral incisors and upper canines (U2 RL; U3 RL, C+R; L2 RL [P < .05]).

Conclusions:

The results indicate that the GHR rs6184 variant is associated with tooth length and ratio dimensions in a Japanese cohort. Further studies utilizing a larger sample size are needed to confirm this finding.
GPR119 Agonism Increases Glucagon Secretion During Insulin-Induced Hypoglycemia
Authors: Li Nina Xiaoyan , Brown Stacey , Kowalski Tim , Wu Margaret , Yang Liming , Dai Ge , Petrov Aleksandr , Ding Yuyan , Dlugos Tamara , Wood Harold B. , Wang Liangsu , Erion Mark , Sherwin Robert , Kelley David E.
Published: April 2018

Insulin-induced hypoglycemia in diabetes is associated with impaired glucagon secretion. In this study, we tested whether stimulation of GPR119, a G-protein–coupled receptor expressed in pancreatic islet as well as enteroendocrine cells and previously shown to stimulate insulin and incretin secretion, might enhance glucagon secretion during hypoglycemia. In the study, GPR119 agonists were applied to isolated islets or perfused pancreata to assess insulin and glucagon secretion during hypoglycemic or hyperglycemic conditions. Insulin infusion hypoglycemic clamps were performed with or without GPR119 agonist pretreatment to assess glucagon counterregulation in healthy and streptozotocin (STZ)-induced diabetic rats, including those exposed to recurrent bouts of insulin-induced hypoglycemia that leads to suppression of hypoglycemia-induced glucagon release. Hypoglycemic clamp studies were also conducted in GPR119 knockout (KO) mice to evaluate whether the pharmacological stimulatory actions of GPR119 agonists on glucagon secretion during hypoglycemia were an on-target effect. The results revealed that GPR119 agonist-treated pancreata or cultured islets had increased glucagon secretion during low glucose perfusion. In vivo, GPR119 agonists also significantly increased glucagon secretion during hypoglycemia in healthy and STZ-diabetic rats, a response that was absent in GPR119 KO mice. In addition, impaired glucagon counterregulatory responses were restored by a GPR119 agonist in STZ-diabetic rats that were exposed to antecedent bouts of hypoglycemia. Thus, GPR119 agonists have the ability to pharmacologically augment glucagon secretion, specifically in response to hypoglycemia in diabetic rodents. Whether this effect might serve to diminish the occurrence and severity of iatrogenic hypoglycemia during intensive insulin therapy in patients with diabetes remains to be established.
Teoria de Piaget: revisão sistemática da produção acadêmica no campo da educação
Authors: Novôa Nicássia Feliciana , Franco Simone Carla Delfino , Silva Helder Antônio
Published: April 2018

Este estudo tem como objetivo a revisão sistemática da literatura brasileira acerca da Teoria de Piaget na área da Educação e Pesquisa Educacional na base de dados da Scielo no período de 2005 - 2014. Esse debate é necessário na medida em que se retrata a relevância dos estudos Piagetianos para a educação. A pesquisa evidenciou a existência de um campo vasto a ser explorado pelos pesquisadores para desenvolver estudos empíricos aplicando a Epistemologia Genética na sua totalidade, dentro dos limites do contexto a ser aplicado, para identificar peculiaridades da realidade dos fenômenos da aprendizagem nos vários contextos e ambientes educacionais no Brasil.
Postural stability and risk of falls per decade of adult life – a pilot study
Authors: Sieńko-Awierianów Elżbieta , Lubkowska Anna , Kolano Piotr , Chudecka Monika
Published: April 2018

A gradual loss of function in the balance system may begin in the fourth decade of life. The effects of this process become visible in old age, when problems with postural stability contribute to falls, making it an important social problem. Early detection of this dysfunction is essential for minimizing the risk of age-related falls, one of the main causes of hospitalization or even death in older adults. The aim of this study was to evaluate somatic factors that may result in the deterioration in postural stability and determine the age range in which the first changes in stability occur. The study included healthy non-sporting adults aged from 20 to 70 years. Four tests based on the Biodex Balance System were used to determine static postural stability, dynamic postural stability, risk of falling and stability limits. The obtained results showed that dysfunctions of dynamic balance appeared significantly earlier than static balance dysfunctions, i.e. as early as at 50 years of age, and then gradually increased. Higher BMI and the percentage and absolute fat content significantly increased the risk of falls and also adversely affected the results of dynamic stability tests.
Metalotolerance Capacity of Autochthonous Bacteria Isolated From Industrial Waste Effluent
Authors: Majolagbe Olusola N. , Adebayo Elijah A. , Ayandele Abiodun , Ezediuno Louis
Published: April 2018

Microbes play significant roles in remediation of heavy metal polluted industrial effluent using the mechanisms of biosorption and bioaccumulation. In the present study, six heavy metal resistant autochthonous bacteria species namely Bacillus cereus, B. megaterium, B. subtilis, Flavobacterium aquatile, Pseudomonas flourescens and Pseudomonas putida were isolated from effluent samples collected from Paper-mill industry (PMI), Paints and Chemicals Industry (PCI), and Steel-rolling Industry (SRI). The isolates were studied for their heavy metal tolerant capacities at different aqueous salt concentrations. Elemental analysis of the industrial effluent samples collected indicated the presence of heavy metals such as Copper (Cu2+), Manganese (Mn2+), Iron (Fe2+) and Lead (Pb2+) at varying concentrations in μg/ml. Generally, there were variations in the minimum inhibitory concentrations (MIC) of the heavy metal salt to each of the bacteria understudy. The MIC value of each of the bacterial isolates to aqueous solution of Cu2SO4 showed that B. megaterium, B. subtilis, Pseudomonas flourescens and Pseudomonas putida had the same MIC value of 20 ± 1.5 μg/mL while Bacillus cereus and Flavobacterium aquatile had MIC values of 13 ± 1.3 μg/mL and 25 ± 2.1 μg/mL respectively. This variation was also noticeable in aqueous salts of Mn2SO4, Fe2SO4 and Pb2SO4.The bacteria isolates showed sensitivity to heavy metals with increasing zone of inhibition as concentration increased with each isolate showing varying degree of metalotolerance. The effectiveness of the autochthonous bacteria as a means to bio-augment the remediation of heavy metal polluted industrial effluent was further proven and recommended.
Language and Outer Space
Authors: Cuțitaru Laura Carmen
Published: April 2018

The 2016 much acclaimed American sci-fi movie Arrival is based on (what is in reality an extension of) the so-called “Sapir-Whorf” hypothesis, a linguistic theory set forth in the first half of the 20th century, according to which one’s native language dictates the way in which one perceives reality. By taking into account the latest in human knowledge, this paper tries to provide arguments as to why such a claim works wonderfully in fiction, but not in science.
Autophagy and virus infection
Authors: Jia Pingdong
Published: April 2018

Autophagy is a highly conserved pathway for physiological metabolism. Bilayer vesicles transport their contents to lysosomes for degradation. Autophagy is therefore a means of removing intracellular viruses and other pathogens in mammalian cells. However, the role of autophagy in virus infection is complex. Several viruses have developed a way to escape autophagy-dependent degradation and replicate themselves through autophagy. This article summarizes the fundamental mechanism and function of autophagy and its role in infection with viruses such as HIV, HTLV-1, and other retroviruses.
Treatment of systemic diseases and oral focal infection
Authors: Liu Bing
Published: April 2018

Oral lesions are highly correlated with the occurrence and development of many diseases. In addition, the treatment of systemic diseases may aggravate oral focal infections, affect the life quality of patients, interfere with the treatment of systemic diseases, and even cause systemic infection in serious cases. Treatment strategies for systemic diseases may induce or aggravate oral local lesion infections. In specific, administration of oral antiepileptic drugs and immunosuppressive drugs may induce gingivitis, radiotherapy or chemotherapy for malignant tumors may cause oral mucositis, long-term use of bisphosphonates for inhibition of tumor bone metastasis or prevention of osteoporosis may cause osteonecrosis of the jaw, and allogeneic hematopoietic stem cell transplantation may cause oral rejection reactions.
Research status of pulmonary infection after renal transplantation
Authors: Zhang Jingfeng
Published: April 2018

Recipients with a low immunity are under a high risk of infection due to the extensive use of immunosuppressive drugs after renal transplantation. Pulmonary infection after renal transplantation is a prevalent postoperative complication characterized by a wide range of pathogens and high mortality. If the disease cannot be diagnosed in time, then the therapeutic effect will not be effective. This article reviews susceptible factors, high onset time, common pathogens, clinical manifestations, and therapy of pulmonary infection after renal transplantation to provide reference for disease prevention and treatment.
Nowhere is Better than Here: The Strengths and Weaknesses of Early Sixteenth Century Utopias
Authors: Noble Tim
Published: April 2018

This article examines the utopian vision present in the eponymous work by Thomas More and in the early Anabaptists. In the light of the discussion on the power and dangers of utopian thinking in liberation theology it seeks to show how More struggled with the tension between the positive possibilities of a different world and the destructive criticism of the present reality. A similar tension is found in early Anabaptist practices, especially in terms of their relationship to the state and their practice of commonality of goods. The article shows that that all attempts to reduce visions of a better world to a particular setting end up as ideological.
In Whose Interest? Ante-Bellum Abolitionism, the Bible, and Contemporary Christian Ethics
Authors: Carson Marion L. S.
Published: April 2018

Christians look to Scripture to inform their ethical decision-making, believing that God speaks through it. However, disagreement as to what the Bible requires us to do can often lead to acrimonious splits within the church. So long as sharp divisions amongst Christians over ethical issues remain, injustices continue, and the reputation of the church is undermined. This article suggests that lessons may be learned from the story of the use of the Bible in the American Abolitionism debate which can help the contemporary church to discuss and perhaps even resolve some enduring ethical questions which are dividing Christians today.
Open-Air Preaching: A Long and Diverse Tradition
Authors: Blythe Stuart
Published: April 2018

For many people, open-air preaching is associated with a particularly limited understanding of the nature of the event. In part this is related to the fact that open-air preaching has received relatively little serious academic study. From a variety of sources, however, it is possible to piece together something of a critically analytic sketch of the practice. This sketch demonstrates that not only can open-air preaching claim longevity but that in turn it is a practice with considerable diversity as open-air preachers seek to make meaning through their gathering and encounter with audiences.
The Place of Theological Education in the Preparation of Men and Women for the British Baptist Ministry then and Now
Authors: Cross Anthony R.
Published: April 2018

Using principally, though not exclusively, the learning of the biblical languages, this paper seeks to demonstrate four things. Firstly, from their beginnings in the early seventeenth century the majority of British Baptists have believed that the study of theology is essential for their ministers, and that the provision of such an education through their colleges is necessary for the well-being of the churches. Secondly, and contrary to misconceptions among Baptists and those of other traditions, Baptists have always had ministers who have been highly trained theologically, and that this has enriched their service as pastors. Thirdly, it reveals that Baptists today have a wealth of both academically-gifted and theologically-astute pastortheologians and pastor-scholars. Finally, it argues that theology has always played its part in the renewal of Christian life and witness for which so many Christians today are praying.
Strangers in the Land and True Lovers of the Nation: the Formation of Lithuanianspeaking Baptist Identity, 1918-1940
Authors: Toth Lina
Published: April 2018

How does an emerging community of faith develop its identity in the context of a semi-hostile and increasingly nationalistic culture? The story of the early years of Lithuanian-speaking Baptists provides an interesting and informative case study. This article focusses on the formative stage of the Lithuanian-speaking Baptist movement during the interwar period of the independent Republic of Lithuania (1918-1940). It considers four main factors which contributed to the formation of Lithuanian-speaking Baptist identity: different ethnic and cultural groupings amongst Baptists in Lithuania; the role of the global Baptist family in providing both material and ideological support; the community’s relationship with the Lithuanian state; and their stance towards the dominant religious context, i.e. the Lithuanian Catholic Church. Out of this dynamic emerges a picture of the particular ways in which these congregations, and especially their leadership, navigated their understanding of loyalty to the Kingdom of God in relation to their belonging to a particular national grouping.
Energy efficiency analysis of styrene production by adiabatic ethylbenzene dehydrogenation using exergy analysis and heat integration
Authors: Ali Emad , Hadj-Kali Mohamed
Published: April 2018

Styrene is a valuable commodity for polymer industries. The main route for producing styrene by dehydrogenation of ethylbenzene consumes a substantial amount of energy because of the use of high-temperature steam. In this work, the process energy requirements and recovery are studied using Exergy analysis and Heat Integration (HI) based on Pinch design method. The amount of steam plays a key role in the trade-off between Styrene yield and energy savings. Therefore, optimizing the operating conditions for energy reduction is infeasible. Heat integration indicated an insignificant reduction in the net energy demand and exergy losses, but 24% and 34% saving in external heating and cooling duties, respectively. When the required steam is generated by recovering the heat of the hot reactor effluent, a considerable saving in the net energy demand, as well as the heating and cooling utilities, can be achieved. Moreover, around 68% reduction in the exergy destruction is observed.
Mathematical modeling of large floating roof reservoir temperature arena
Authors: Liu Yang , Fan Jiawei , Cheng Qinglin
Published: April 2018

The current study is a simplification of related components of large floating roof tank and modeling for three dimensional temperature field of large floating roof tank. The heat transfer involves its transfer between the hot fluid in the oil tank, between the hot fluid and the tank wall and between the tank wall and the external environment. The mathematical model of heat transfer and flow of oil in the tank simulates the temperature field of oil in tank. Oil temperature field of large floating roof tank is obtained by numerical simulation, map the curve of central temperature dynamics with time and analyze axial and radial temperature of storage tank. It determines the distribution of low temperature storage tank location based on the thickness of the reservoir temperature. Finally, it compared the calculated results and the field test data; eventually validated the calculated results based on the experimental results.
Clinical Significance of the Cerebral Perforating Arteries
Authors: Antunović Vaso , Mirčić Aleksandar , Marinković Slobodan , Brigante Luciano , Mališ Miloš , Georgievski Biljana , Aksić Miljana
Published: April 2018

There is scarce data in the contemporary literature regarding the correlation of the microanatomy of the perforating arteries, their atherosclerosis, and the ischemia in their territory. In order to examine, at least partially, those parameters, the perforating arteries of 12 brains were microdissected or their vascular casts were obtained. In addition, 30 specimens of the perforators were used for a histological and immunohistochemical study. Finally, radiological images of 14 patients with deep cerebral infarcts were examined following a selection among 62 subjects. It was found out that certain groups of the perforators ranged in number between 0 to 11 (1.1-8.4 on average). In addition to the origin from the parent vessels, some of the perforators also arose from the leptomeningeal branches. Occlusion of such a branch may result in both a superficial and a deep ischemic lesion. Besides, the common stems of certain perforators supplied both right and left portions of the corresponding brain regions. Occlusion of such a common trunk leads to bilateral infarction. The atherosclerosis of the perforating vessels, which was found in one third of the specimens, is the basis for the ischemic lesions development on their territory. Among the 62 patients with ischemic lesions, 14 had a deep cerebral infarcts, most often within the thalamus, as well as on the territory of the middle cerebral and the anterior choroidal artery perforators of the hemispheres. Our study showed that a strong correlation exists between certain microanatomical features, atherosclerosis, and region of supply of the perforating arteries, on the one hand, and location of the ischemic lesions on the other hand.
Evaluation of the Role of ABCB1gene Polymorphic Variants on Psychiatric Disorders Predisposition in Macedonian Population
Authors: Naumovska Zorica , Nestorovska Aleksandra K. , Sterjev Zoran , Filipce Ana , Grozdanova Aleksandra , Dimovski Aleksandar , Suturkova Ljubica , Serafimoski Vladimir
Published: April 2018

The psychiatric and other CNS disorders are characterized with unregulated neuro-inflammatory processes and chronic microglia cell activation resulting with detrimental effect. ABCB1gene polymorphismsC1236T, G2677T/Aand C3435T are associated with P-glycoprotein expression and function andare linked with predisposition to psychiatric disorders such as schizophrenia and bipolar disorders. The relationship between mood disorders and glucocorticoids has been confirmed and ABCB1 SNPs influence the glucocorticoids access to the brain.

The aim of the study is evaluation of the influence of the three most common ABCB1SNPs on predisposition to psychiatric disorders in Macedonian population.

In the study 107 unrelated healthy Macedonians of both sexes were enrolled as a control group and patient population of 54 patients (22 to 65 years old) diagnosed with schizophrenia or bipolar disorder. ABCB1 for three polymorphisms were analyzed by Real-Time PCR in both groups.

The results have confirmed the role of the ABCB1 gene in predisposition to psychiatric disorders and increased risk of developing bipolar disorder in carriers of the heterozygotes and mutant homozygotes for polymorphic variations in 1236 and 2677 in comparison to the normal genotype carriers. Three-fold higher risk was estimated for psychiatric illness in women that are 1236 and 2677 heterozygous carrier (heterozygous and mutant homozygous) compared to healthy control (men and women) population and four-fold higher risk in comparison only to healthy women population. Mutant allele carriers for 1236 and 2677 polymorphisms that are 35 years and below in patients population have almost three-fold higher risk for development of psychiatric illness.
Factors That Influence Surgical Margin State in Patients Undergoing Cold Knife Conization – A Single Center Experience
Authors: Aluloski Igor , Tanturovski Mile , Petrusevska Gordana , Jovanovic Rubens , Kostadinova-Kunovska Slavica
Published: April 2018

Aim: To evaluate the factors that influence the surgical margin state in patients undergoing cold knife conization at the University Clinic of Gynecology and Obstetrics in Skopje, Republic of Macedonia

Materials and methods: We have retrospectively analyzed the medical records of all patients that underwent a cold knife conization at our Clinic in 2015. We cross-referenced the surgical margin state with the histopathological diagnosis (LSIL, HSIL or micro-invasive/invasive cancer), menopausal status of the patients, number of pregnancies, surgeon experience, operating time and cone depth. The data was analyzed with the Chi square test, Fisher’s exact test for categorical data and Student’s T test for continuous data and univariate and multivariate logistical regressions were performed.

Results: A total of 246 medical records have neen analyzed, out of which 29 (11.79%) patients had LSIL, 194 (78.86%) had HSIL and 23 (9.34%) patients suffered micro-invasive/invasive cervical cancer. The surgical margins were positive in 78 (31.7%) of the patients. The average age of the patients was 41.13 and 35 (14.23%) of the patients were menopausal. The multivariate logistic regression identified preoperative forceps biopsy of micro-invasive SCC, HSIL or higher cone specimen histology and shorter cone depth as independent predictors of surgical margin involvement in patients undergoing cold knife conization.

Conclusion: In the current study, we have found no association between the inherent characteristics of the patient and the surgeon and the surgical margin state after a CKC. The most important predictors for positive margins were the severity of the lesion and the cone depth.
Comparative Analysis of Determining the Market Value of Forest Real Properties Using Various Valuation Techniques
Authors: Buśko Małgorzata
Published: April 2018

The paper presents procedures for determining market values of forest real properties, with particular emphasis placed on the forest stand. The mixed-approach valuation procedure - land valuation index method - was analyzed. The practical part of the work regarding the valuation of the forest stand introduces the various techniques of valuation and acquisition of data on forest resources used, i.e.: index-based valuation approach and stock survey approach.

The subject of the research is part of a forest property, which represents an assessment area, typical of the southern part of Poland, located in the Tenczynek Forest Division. There is a forest management plan for the analyzed property which, together with the assessment descriptions, was used as one of the sources of data for valuation. The second source of data for valuation were direct field surveys, i.e.: geodetic surveys for determining the assessment area and the stock survey approach with individual tree assessment with respect to data on the stand.

Based on the research, it may be concluded that both valuation techniques and methods used to capture data on forest resources significantly affect the final value of forest properties. The market value of the stand, determined by the index-based valuation approach, demonstrates a significant difference when compared to the value of the stand determined by the stock survey approach. The forest management plan should only be used as a supplementary material and only to identify site types of forests by property valuers and, partially, together with economic maps, to determine the boundaries of assessment areas.
The Transactional Assets Pricing Approach and Income Capitalization Models in Professional Valuation: Towards a “Quick” Income Capitalization Format
Authors: Michaletz Vladimir B. , Artemenkov Andrey
Published: April 2018

The transactional assets pricing approach within valuation theory (TAPA) reviewed in this paper and developed by the authors, now more than a decade ago (MICHALETZ, ARTEMENKOV A. & ARTEMENKOV L., (2007), has found many applications in professional valuation practices dealing with illiquid assets (Leyfer 2006; Andrews 2011)). Consequently, challenges have arisen to ascertain its performance and develop tools, on its basis, which can be employed by valuers in their everyday practice and which are aligned as much as possible with the income approach tools used by them in their professional work. This paper proposes modifications to the standard direct income capitalization technique to align it as closely as possible with the results derivable under the applications of the TAPA basic pricing formula. The authors develop the respective adjustments using the Taylor series expansion and then, using a simulation technique, outline the performance of the resulting modified (“quick”) income capitalization model against the TAPA benchmark. The findings indicate that such a modified (“quick”) income capitalization approach has reasonable accuracy, which makes it amenable to direct usage in valuation practice, given the described assumptions.
Testing Fiscal Dominance Hypothesis in a Structural VAR Specification for Pakistan
Authors: Shaheen Rozina
Published: April 2018

This research aims to test the fiscal dominance hypothesis for Pakistan through a bivariate structural vector auto regression (SVAR) specification, covering time period 1977 – 2016. This study employs real primary deficit (non interest government expenditures minus total revenues) and real primary liabilities (sum of monetary base and domestic public debt) as indicators of fiscal measures and monetary policy respectively. A structural VAR is retrieved both for entire sample period and four sub periods (1977 – 1986, 1987 – 1997, 1998 – 2008, and 2009 – 2016). This study identifies the presence of fiscal dominance for the entire sample period and the sub period from 1987 – 2008. The estimates reveal an interesting phenomenon that fiscal dominance is significant in the elected regimes and weaker in the presence of military regimes in Pakistan. From a policy perspective, this research suggests increased autonomy of central bank to achieve long term price stability and reduced administration costs to ensure efficient democratic regime in Pakistan.
Karayaka Koyunlarında Gonadotropin Salgılatıcı Hormon Uygulamasının (GnRH) Ovaryum Aktivitesi Üzerine Etkisi
Authors: Soydan Ercan , Şen Uğur
Published: April 2018

Bu çalışmanın amacı, Karayaka koyunlarında dönem içi gonadotropin salgılatıcı hormon (GnRH) uygulamasının kızgınlık gösterme oranı ve ovaryum aktivitesi üzerine etkisini belirlemektir. Çalışmada en az iki doğum yapmış ve benzer vücut ağırlığına sahip 20 baş Karayaka ırkı koyun hayvan materyali olarak kullanılmıştır. Deneme başında tüm koyunlara ovaryum üzerinde mevcut olabilecek olan korpus luteum (CL)‘un yıkımı için 1 ml PGF2Î± kas içi enjekte edilmiştir. PGF2Î± uygulamasından 9 gün sonra ise koyunlar rastgele iki eşit gruba ayrılmıştır. Birinci gruptaki koyunlara (n=10) 40 mg flugestone asetat içeren sünger vajina içine yerleştirilmiştir ve bu uygulamadan 14 gün sonra süngerler çıkartılarak, 1 ml PGF2Î± kas içi enjekte edilmiştir. PGF2Î± enjeksiyonunu takiben 36 saat sonra 1 ml GnRH kas içi enjekte edilmiştir. İkinci gruptaki koyunlara (n=10) ise mevcut olabilecek olan korpus luteum (CL)‘un yıkımı için 1 ml PGF2Î± kas içi enjeksiyonun dışında herhangi bir uygulama yapılmamış olup, bu grup çalışmamızın kontrol grubunu oluşturmuştur. Bu işlemleri takiben her iki gruptaki bütün koyunlar Karayaka koçuna verilmiş ve 72 saat boyunca kızgınlık gösteren koyunlar belirlenmiştir. Kızgınlık taramasının sonunda bütün koyunlar kesime sevk edilmiş ve her iki ovaryum üzerindeki küçük (1-3 mm), büyük (>3 mm) ve toplam folikül sayısı ve CL sayısı belirlenmiştir. GnRH uygulaması yapılan koyunlar (%100) kontrol grubundaki koyunlara (%70) göre daha yüksek oranda kızgınlık göstermişlerdir. GnRH uygulaması yapılan koyunların her iki ovaryumundaki küçük ve toplam folikül sayısının ve CL sayısının, kontrol grubundaki koyunlarınkinden daha yüksek olduğu tespit edilmiştir. Ancak büyük folikül sayısı bakımından deneme grupları arasında bir farklılık tespit edilmemiştir. Sonuç olarak bu çalışmada mevsim içi dönemde Karayaka koyunlarında sünger uygulaması sonrasındaki GnRH uygulamasının kızgınlık gösterme oranını yükselttiği ve ovaryum aktivitesini arttırdığı tespit edilmiştir.
Alternative Facts and the ICER Proposed Policy on Access to Imaginary Pharmacoeconomic Worlds
Authors: Langley Paul
Published: April 2018

The Institute for Clinical and Economic Review (ICER) announced at the end of March 2018 that it proposed to share executable draft economic models with relevant drug manufacturers during ICER evidence reviews. Taken at face value, ICER is offering manufacturers and other interested parties the possibility of a greater involvement in the assessment of modeled claims for product pricing. The purpose of this commentary is to point to the obvious limitations to this policy and to raise questions as to the extent to which ICER is willing to commit to transparency in the creation of modeled claims. While a commitment to greater transparency is to be welcomed, the fact remains that the ICER methodology does not meet the standards of normal science. ICER modeled claims not only lack credibility but are impossible to evaluate or replicate in treating environments. In proposing greater transparency ICER runs the risk of undermining its own credibility. If manufacturers have the opportunity to generate alternative models which create alternative claims, then ICER runs the risk of its pole position in health technology assessment being questioned. Rather than focused on non-evaluable lifetime modeled claims, there is the opportunity for ICER to reject its current business model, accepting instead a modelling paradigm that is consistent with the standards of normal science.

 

Type: Commentary
An Accurate Handwritten Digits Recognition system Based on DWT and FCT
Authors: S. Kadhm Mustafa , Enteesha Mhawi Duaa , Mohammed H. Zaki Rana
Published: April 2018

In this paper an accurate Indian handwritten digits recognition system isproposed. The system used three proposed method for extracting the most effectingfeatures to represent the characteristic of each digit. Discrete Wavelet Transform(DWT) at level one and Fast Cosine Transform (FCT) is used for features extractionfrom the thinned image. Besides that, the system used a standard database which isADBase database for evaluation. The extracted features were classified with KNearestNeighbor (KNN) classifier based on cityblock distance function and theexperimental results show that the proposed system achieved 98.2% recognitionrate.
A Comprehensive Case Study of a Frontal Mineral Dust Storm in spring over Iraq
Authors: O. Roomi Thaer , N. Zeki Khawla , F. Hassoon Ahmed
Published: April 2018

Dust storms are among the most important weather phenomena in Middle East. The Shamal dust storms are dominated across Iraq and the whole Middle East, especially in summer. However, frontal type of dust storms is possible in winter and spring. In this research, a comprehensive case study was conducted to a dust storm that occurred on 20 March 2016 from many perspectives: synoptic, satellite imagery, dust concentration analysis, visibility reduction, and aerosol optical depth. The study shows that the dust storm initiated inside Syria and moved eastward with the movement of the front. Dust concentrations and aerosol optical depth were also discussed that simulate the dust storm over Iraq in a reasonable way with some differences. The dust concentrations values increase gradually during the early hours of 20 March at 1200 UTC to become within (200-5000) . The dust concentrations comparison with some surrounding countries shows that Iraq had the maximum value at the dust storm time. An experimental relationship to calculate the dust concentration from visibility was tested according to the multi-model products and revealed acceptable estimates. Dust aerosol optical depth offers good means to quantify the dust amount in the Middle East where the dust is the determining factor. Additional investigation was done by using the relative vorticity and the potential vorticity. The results of this investigation show that there are upper shortwaves that are responsible of strengthening of the low pressure system at the surface. The computed value of potential vorticity advection was estimated to be about (2.7×10-4 K m2/kg s) along a distance of about 500 km which suggested a high value of divergence east of the system which lead to a significant updraft.
Modelo neoliberal: cultura del simulacro y negación del bien común
Authors: Torres Jofré Mario
Published: April 2018

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Las categorías conceptuales que permiten la enseñanza de la Geografía
Authors: Pérez-Cisternas Nataly
Published: April 2018

Los procesos de conceptualización de la geografía son centrales para el desarrollo de las habilidades de pensamiento espacial en los estudiantes. La revisión de literatura a presentar examina las formas en que se enseña la geografía, develando la relevancia de los conceptos centrales que permiten generar en los estudiantes este raciocinio espacial. Se considera que existen cinco categorías conceptuales de análisis espacial: Lugar, Paisaje, Territorio, Región y Medioambiente. Por tanto, los artículos revisados se asocian a las discusiones e investigaciones a partir de estas categorías. 

La selección para esta revisión de literatura se definió a partir de cinco criterios: temporal, publicación en base de datos WoS, palabras claves de búsqueda asociadas a las categorías conceptuales de análisis espacial, publicaciones asociadas a comunidades científicas y contextos de enseñanza, lo que permitió definir una cantidad de quince artículos, donde diez de estos son empíricos y cinco teóricos. Se establece una organización en el análisis relacionado con la presentación de jerarquías y metodologías en la utilización de las categorías conceptuales en dos ámbitos relacionados con la enseñanza de la geografía, la formación de profesores y la enseñanza escolar.

Palabras clave: Espacio, categorías conceptuales de análisis, pensamiento espacial, enseñanza de la geografía.