bluuebunny/crossref_metadata_2025 huggingface dataset:
Bone mineral density and bone microarchitecture assessment using trabecular bone score in Acromegaly
Authors: Boro Hiya , Nagendra Lakshmi , Mondal Sunetra , Mannar Velmurugan , Alam Sarah , Kubihal Suraj , Dogra Vinay , Khatiwada Saurav , Malhotra Rakhi
Published: February 2023

Purpose
We aimed to analyze the bone mineral density (BMD) and bone microarchitecture using the trabecular bone score (TBS) in acromegaly and compare it with healthy controls.
Methods
The current study included 50 patients with active acromegaly and 50 age and sex-matched controls. Biochemical parameters were analyzed using standardized techniques. BMD was assessed using dual-energy X-ray absorptiometry (DXA). (Discovery A 84023, Hologic Inc, MA, USA). TBS of the lumbar spine was measured using TBS iNsight software (version 3.0.2.0, medimaps, Merignac, France) installed on the same DXA machine.
Results
Acromegaly patients had a significantly greater lumbar spine [(1.026 ± 0.180) g/cm2 vs (0.951 ± 0.108) g/cm2, p=0.014], femoral neck [(0.879 ± 0.136) g/cm2 vs (0.780 ± 0.110) g/cm2, p<0.001], and total hip BMD [(1.013 ± 0.128) g/cm2 vs (0.917 ± 0.118) g/cm2, p<0.001] than healthy controls while no significant difference was observed in the distal radius BMD [(0.700 ± 0.102) g/cm2 vs (0.698 ± 0.087) g/cm2, p=0.890] and TBS [(1.348 ± 0.086) vs (1.345 ± 0.091), p=0.890].
No significant difference was observed in the TBS between eugonadal and hypogonadal acromegaly cases, be they male or female. On multiple linear regression analysis, ‘age’ and ‘lumbar spine BMD’ were found to predict TBS in acromegaly.
Conclusion
Our study showed no difference in TBS between acromegaly and controls, irrespective of gender and gonadal status. Further studies (longitudinal) with the involvement of a large sample size are required to analyze the utility of TBS in the prediction of skeletal health and fracture risk in acromegaly.
Association between urinary methylparaben level and bone mineral density in children and adolescents aged 8-19 years
Authors: He Huan , Li Min , Liu Bailing , Zhang Zhan
Published: February 2023

Background
Previous epidemiological studies have explored the relationships between methylparaben (Mep) and bone mineral density (BMD) in adults. However, the correlation between methylparaben and BMD in children and adolescents is unclear.
Objective
This study examined the correlation between Mep and BMD in children and adolescents aged 8–19 years.
Methods
Data on urinary Mep levels and BMD (containing total BMD, trunk bone BMD, pelvis BMD, lumbar spine BMD and thoracic spine BMD) of 1,830 children and adolescents aged 8–19 years were obtained from the 2011–2016 National Health and Nutrition Examination Survey (NHANES) database. Multivariable linear regressions and smooth curve fittings were adopted to evaluate the correlation between Mep and BMD.
Results
After adjusting potential confounders, we found positive relationship between Mep and BMD. Furthermore, the positive trends were significant in females aged 8–19 years, but not significant in males aged 8–19 years (P for trend > 0.05).
Conclusion
This study has been the first study that found evidence to demonstrate that exposure to Mep may be related to BMD in children and adolescents aged 8–19 years. More population and experimental studies should be performed to verify the above findings and analyze the mechanism.
HDAC3 deficiency in macrophage attenuates acute lung injury by inhibiting cGAS-mediated pyroptosis in a miR-4767-dependent manner
Authors: Li Ning , Liu Bohao , He Ruyuan , Li Guorui , Xiong Rui , Fu Tinglv , Li Donghang , Wang Bo , Geng Qing
Published: February 2023

Activated inflammation and pyroptosis in macrophage are closely
associated with acute lung injury (ALI). Histone deacetylase 3
(HDAC3) serves as an important enzyme that could repress gene
expression by mediating chromatin remodeling. Here, we aim to
explore the role and potential molecular basis of HDAC3 in
lipopolysaccharide (LPS)-induced ALI. We found that HDAC3 was
highly expressed in lung tissues of LPS-treated mice and in
LPS-induced macrophages. Lung tissues from macrophage
HDAC3-deficient mice stimulated with LPS showed alleviative lung
pathological injury and inflammatory response. HDAC3 silence by
small interfering RNA (siRNA) significantly blocked the activation
of cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes
(STING) pathway while HDAC3 overexpression by adenovirus
transfection significantly promoted the activation of cGAS/STING
pathway and aggravated pyroptosis in LPS-induced macrophage.
However, HDAC3 silence or overexpression at baseline showed no
effects on the level of mitochondrial DNA (mt-DNA) and the
activation of cGAS/STING pathway. But HDAC3 at baseline could
change the mRNA and protein levels of cGAS. Additionally, autophagy
or proteasome inhibition in LPS-induced macrophages transfected
with Hdac3 siRNA did not affect the protein level of cGAS.
Mechanistically, cGAS was a direct target gene of miR-4767 in
macrophage. LPS could recruit HDAC3 and H3K9Ac to the miR-4767 gene
promoter, which repressed the expression of miR-4767 by decreasing
histone acetylation of the miR-4767 gene promoter. To this end,
intratracheal administration of liposomes loaded with
Hdac3siRNA prevented mice from LPS-induced lung injury and
inflammation. Taken together, our findings demonstrated that HDAC3
played a pivotal role in mediating pyroptosis in macrophage and ALI
by activating cGAS/STING pathway through decreasing histone
acetylation of the miR-4767 gene promoter. Targeting HDAC3 in
macrophage may provide a new therapeutic target for the prevention
of LPS-induced ALI.
An Investigation of the Implementation of the Dual Vocational Education and Training: Field Studies in Six Vocational Colleges
Authors: Van BUI Thi Thanh
Published: February 2023

In recent years, Vietnamese Vocational Education and Training (VET)system has been employed with numerous reforms, especially the adoption of the German Dual VET. In the current context of globalization, Vietnam now requires high-quality manpower more than ever. By far, most VET-related studies have provided overall scenarios on Vietnam’s VET but there has been no real investigation at vocational institutions. This research aimed to answer two questions: (1) To what extent does the number of affiliate enterprises affect the effectiveness of Vietnamese Dual VET?, (2) How effective is on-the-job (OJT) training curriculum of the Dual VET system toward enhancing the qualification of Vietnamese workers? Targeting the key industrial zones in all three regions of Vietnam where industries are concentrated and attract many workers, this study conducted an investigation at six vocational colleges in five provinces that have been implementing the dual model. Under the mixed method approach, the data were triangulated in the convergence framework of analysis. By conducting online questionnaires with570 vocational students and 17 semi-structured interviews with vocational educators and enterprises' managers, this research explored the real status of the job-oriented training in sampled vocational colleges.The most frequent form of questions used for the questionnaire of this study was the Likert scale, which resulted in ordinal data. As for the large number of scaled questions, the researcher decided to analyze the internal consistency (reliability) of the scales by calculating Cronbach’s alpha coeficient. The α coefficients of the three scales used in the research, including “Facilities & Equipment of the college”, “Business Association Activities”, and “OJT evaluation” are 0.853, 0.940, and 0.925, respectively, which are all excellent levels of internal consistency. The following findings were discovered: (i) most of the sampled vocational students did not have positive feedback toward OJT; (ii) a higher number of partner enterprises indicates the better quality of OJT; and (iii) a high-quality OJT is a key factor in facilitating the sustainable development of the Vietnamese Dual VET system. From those the author raised some policy recommendations to move forward with the improvement of the dual VET quality and enhancement of the workforce.
3D Imaging Reconstruction Can Recognize Functional Tissue and Predict Liver Failure.
Authors: Vicente Emilio , Quijano Yolanda , Duran Hipolito , Diaz Eduardo , Fabra Isabel , Malave Luis , Ruiz Pablo , Pizzuti Giada , Naldini Chiara , De Nobili Giovanni , Caruso Riccardo , Ferri Valentina
Published: February 2023

Background: The aim of this study is to evaluate the future liver remnant after major hepatectomy with 3D modelling treated, respectively, with associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) and portal vein embolization (PVE).
Methods:
Patients submitted to ALPPS at our centre were compared with a group of patents submitted to the PVE followed by major hepatectomy. 3D reconstruction was realised before and after surgical treatment, and anatomic future liver remnant (FRL) and functional future liver remnant (FRFx) were calculated and compared with clinical outcomes.
Results:
From May 2011 to October 2019, 11 ALPPS procedures were realised at Sanchinarro University Hospital, Madrid. They were compared to a control group composed of 13 patients who underwent PVE followed by hepatectomy. The increase of anatomical FRL (iFRL) was superior in the ALPPS group (120%) with respect to the PVE group (73%) (p=0,041), while the increase of functional FRFX (iFRFx) was 35% in the ALLPS group and 46% in the PVE group (p>0,05), showing no difference in the two groups. PHLF grade B and C occurred in 6 patients. The ROC curve showed a better AUC for FRFxVpost (74%) with respect to FRLVpost (54%) in prediction PHLF>B.
Conclusion: The 3D reconstruction model can allow optimal surgical planning, and through the use of specific algorithms, can contribute to differential functioning liver parenchyma of the FLR.
Elbow hemiarthroplasty with a 3D-printed megaprosthesis for distal humeral bone defects after tumor excision: A cases report
Authors: Zhu Yingkang , Gong Shuo , Dai Jin , Zhou Lei
Published: February 2023

Background: The distal humerus is a rare site for primary and metastatic bone tumors. The therapeutic reconstruction modality of bone defects after tumor resection around the elbow remains extremely challenging at present. Therefore, due to the scarcity of cases and lack of standardized surgical strategies, it is often difficult for surgeons to choose the right choice. The application of 3D-printed megaprosthesis with hemiarthroplasty for the treatment of the distal humerus after tumor resection can be a very effective option.
Case presentation: We present a clinical case of a 3D-printed distal humeral megaprosthesis for treatment of bone defects caused by metastatic bone tumors. The patient suffered a pathological fracture due to metastatic tumor invading the distal humerus, which affected daily life because of significantly limited pain activity. Preoperative evaluation was aggressively performed, and the decision was made to distal humeral hemi-arthroplasty (DHH) after wide resection of the tumor segment bone. Processing of the Digital Imaging and Communications in Medicine (DICOM) data from CT scans performed after mirror conversion using CT data of the contralateral humerus, we designed a 3D-printed distal humeral megaprosthesis with hemiarthroplasty. After reconstruction of bone and surrounding soft tissue by the 3D-printed megaprosthesis combined with the LARS ligament and regular follow-up for 12 months, the patient had an MSTS-93 score of 29 and an MEPs of 100, which reached a good level, and the patient was fully competent in normal daily activities.
Conclusions: Our results show that the 3D-printed modular megaprosthesis with hemiarthroplasty is a very effective option for cases large elbow bone defects due to primary bone tumors or metastatic disease. However, careful preoperative preparation is required for the best outcome. Careful preoperative preparation and long-term follow-up are essential for the best outcome.
Gall-Forming Nematode, Anguina Woodi (Nematoda: Anguinidae), Gall Midge Mitodiplosis Graminis (Diptera: Cecidomyiidae) And Chalcid Wasp, (Hymenoptera: Eurytomidae) On Dune Grass From the Western Cape, South Africa
Authors: Chauke Tinyiko , Subbotin S. A. , Maseko Z. , Mamabolo M. M , Swart A. , Malatji Petunia
Published: February 2023

In 2021/2022, galls formed by a nematode, Anguina woodi were found on the stems, leaves and leaf sheaths of dune grass, Ehrharta villosa Schult. var. villosa on Milnerton Beach, Blouberg Beach and Langebaan Nature Reserve, Western Cape Province, South Africa. These galls were spongy in texture, deep purple to blackish in color and non-pedunculate. They were found in clusters, but also as single entities. Larger, harder galls varying from beige to dark brown in colour, apparently caused by insects, were also found on the stems of dune grass at Blouberg Beach and Langebaan Nature Reserve. Some nematode galls were found immediately next to, or on top of the insect galls. Those found on top of insect galls seemed to be harder and drier than those found on stems not infected by insect galls. The co-infection of insects and anguinid nematodes has not been reported from the current study areas and was thus included in the present study. Both molecular and morphological studies were conducted on the nematodes and insects leading to that a host specific, gall forming nematode was identified from all three localities; the gall-forming insects were identified morphologically and molecularly to family Eurytomidae (Hymenoptera) and the gall midge Mitodiplosis graminis Kieffer (Diptera: Cecidomyiidae). No insect galls were found on dune grass from Milnerton Beach. The paper includes speculations on a probable association between nematodes and insects
Porous Bleed Boundary Conditions for Supersonic Flows with & without Shock-Boundary Layer Interaction
Authors: Giehler Julian , Grenson Pierre , Bur Reynald
Published: February 2023

In this paper, several existing porous bleed models are implemented into the in-house RANS-solver elsA, and their performance are evaluated on two different flow cases. Reference simulations are performed to evaluate the accuracy of the applied bleed models and to show the lack of modeling different plate geometries. The models significantly differ in predicting the bleed mass flux along the plate. For the turbulent supersonic boundary layer bleeding, the reference simulations demonstrate a hole diameter influence on the flow, but none of the models considers this effect. The model of Slater fits well with the reference simulation by applying it to its extracted data. However, applying the bleed models as a boundary condition results in more significant deviations from the reference simulation, leading to an overestimation of the wall shear stress and fuller boundary layer profiles downstream of the bleed region. Additionally, in the second flow case, including the shock-boundary layer interaction, the effect of the porous bleed is overestimated. No model is found suitable for a shock-boundary layer interaction control, and essential parameters such as the bleed hole diameter are not considered.
Hydrological effects on Rainfall-Induced Slope instability: A Case Study
Authors: Gidon J. S , Sahoo S
Published: February 2023

Real-time monitoring of the slope will give the actual slope assessment and according to the data received the slope behavior can be analyzed. Monitoring the soil slope behavior is essential to understand the slope section's failure mechanism. According to NDMA (National Disaster Management Authority) report, 2019–2020, 15% of the landmass in India is prone to landslides. The measurement of pore water pressure and site displacement for different rainfall intensities can be obtained. Measuring the performance of the slope and hydrological conditions will give more understanding of the underlying problem of slope behavior. Proper instrumentation during real-time monitoring of the slope can provide a proper understanding of the failure mechanism of the soil slope and the development of the failure surface due to seepage of rainwater. Reduction of the catastrophic effect can be achieved by having a proper insight into the slope behavior. The positions of tensiometers placed at different levels of the slope shows the significance of pore water pressure developed not only due to presence of groundwater table but that developed during rainfall period. Finite element (FE) analysis can be performed for validation of the results obtained from the field study. The potential slip surface of the slope determined from the analysis shows the location at which the slope failure can potentially occur. The simulation shows that the FE based study present here can be used in other slope study as well. A reliable and sustainable slope stabilization technique has been developed to tackle slope instability due to rainfall in the study area using the field data and the FE analysis. A threshold level can be identified by the system providing advanced warning criteria for the area.
Yttrium decorated fullerene C30 as potential hydrogen storage material: Perspectives from DFT simulations
Authors: Paul Debolina , Mane Pratap , Sarkar Utpal , Chakraborty Brahmananda
Published: February 2023

Using the density functional theory method, hydrogen storage capacity for Yttrium doped fullerene has been studied. Bonding of Y atom with that of C30 is due to the charge transfer taking place from the d-orbital of the Y atom to the 2p-orbital of the C atom of C30. It has been predicted that a single Y atom can adsorb 7 hydrogen molecules, whose binding energy falls within the range as suggested by the U.S. Department of Energy (DOE). Interaction of hydrogen on the metal is because of the Kubas interaction where charge donation occurs from the metal d-orbital to the hydrogen 1s-orbital and there is also back donation as a result the hydrogen adsorption energy is more than physisorption. However, H atoms in the H2 molecule is not getting dissociated, only a small elongation of H-H bond in the H2 molecule is observed. The gravimetric weight percentage for 5 Y atoms loaded fullerene C30, with each Y atom adsorbing 7 H2 molecules is recorded to be 8.060%, higher than the limit of 6.5% by DOE. These findings suggest Y doped fullerene C30 may be considered as a potential candidate for hydrogen storage devices.
Synthesis of N-monosubstituted ureas in a mixture of choline chloride and Aluminium nitrate as a green and selective process
Authors: jafari mohammadreza , Darvishi Atefeh , Heydari akbar
Published: February 2023

The reaction of benzyl alcohol or benzyl halide with urea in a mixture of choline chloride and aluminum nitrate ionic liquid as a solvent resulted in the formation of N-monosubstituted urea products. This reaction was achieved good to excellent yields for a number of derivatives of benzyl alcohols and benzyl halides under the reaction conditions. Since the resulting products were so polar and insoluble in water, they were easily separated from the reaction medium by adding water to the reaction mixture. Therefor such ionic liquid provided a facile and selective route for the synthesis of pharmaceutically and industrially substantial compounds.
Error analysis for calculation methods of shear capacity of FRP reinforced concrete beams without web reinforcement based on database
Authors: Wang Tao , Fan Xiangqian , Gao Changsheng , Qu Chiyu , Liu Jueding
Published: February 2023

The existing calculation methods of shear capacity of FRP reinforced concrete beams without web reinforcement are inconsistent in considering the factors of shear capacity, and there are different degrees of conservative calculation. Based on the experimental data of shear capacity in published literatures at home and abroad, a database with a sample size of 461 was established in this paper. The effects of six factors, such as the compressive strength of concrete, the width of the beam, the effective depth of the beam, the shear span to depth ratio, the reinforcement ratio of FRP bars and the elastic modulus of FRP bar, on shear capacity were analyzed comprehensively, and the prediction effect of each calculation method was evaluated. The results showed that the influence of each calculation method on the size effect and shear span to depth ratio was not consistent, and there were different degrees of conservative calculation, there was a good correlation between the factors and the shear capacity; among the design provisions recommended by different countries, the CSA/CAN-S806-2012 has a more accurate prediction effect, and the ACI440.1R-2015 has the most conservative prediction effect; among the calculation models provided by scholars, the prediction effect of Ahmed-2021 is more accurate, and that of Alam-2013 is the most conservative. The research results provided the certain referential value for developing the calculation method of shear capacity of FRP reinforced concrete beams without web reinforcement.
Impact of Flipped Classroom on EFL Learners' Self- Regulated Learning and Higher-Order Thinking Skills during the Covid19 Pandemic
Authors: Samadi Fatemeh , Jafarigohar Manoocher , Saeedi Masood , Ganji Mansoor , Khodabandeh Farzaneh
Published: February 2023

With the emergence of innovative online-based tools, new opportunities have emerged to improve the quality of language learning. The current study investigated the impact of flipped classroom on enhancing EFL learners’ cognitive and meta-cognitive competence. To this end, two groups of participants were selected for the two phases of the study and for comparing the impact of flipped classroom and conventional modes of instruction on enhancing EFL learners' self-regulated learning strategies and higher order thinking, two different sample sizes were needed. For the research questions, two groups of homogenous language learners were needed. The participants were selected from two private language institutes in Arak, Iran. To elicit the required data, multiple sources of data collection, Including Language proficiency test, the Self-Regulation Questionnaire, flipped classroom attitude questionnaire, Higher-order Thinking Skills Test, were used. The findings revealed that flipped classrooms significantly affect the learners' use of the subcategories of cognitive self-regulated learning strategies and also it can be concluded that the flipped classroom supports students in becoming self-directed learners. With regard to the impact of Flipped classroom on enhancing EFL learners’ higher-order thinking skills, it could be inferred that Flipped classrooms significantly affect the EFL learners’ use of evaluating, analyzing, and creating.
Novel Electrchemical Polymerization of Aminofluorenone and its Electrochemical behavior on Glassy Carbon Electrode
Authors: Asswadi F. A. , Azeem Magdi , qasem Jameel
Published: February 2023

Electropolymerization of 1-aminofluorenone, AFO, was prepared in CH2Cl2 and Bu4NClO4 solution as the electrolyte, via constant potential electrolysis. The redox behaviour of aminoflourenone(AFO) was investigated in methylene chloride as asolvent electrolyte medium using cyclic voltammetry (CV) of AFO polymer deposit on the electrode surface. Film formed through continuous cyclic voltammograms and the activity of film formed studied in aqueous solution. Factors affecting on the film formation by successive potential scans like potential limits, scan rate, number of cycles, monomer concentrations, the product was characterized by CV, Chronocoulometry techniques and FT-IR spectra, were examined in details to suppose the mechanism. To the best of knowledge, this is the first article on direct anodic oxidation of PAFO on saturated calomel electrode.
IoT herd monitoring: an opportunity facing the Iberian mountain challenges
Authors: Castro José , Castro Eduardo , Castro Marina
Published: February 2023

Pastoralism is essential for conserving the Iberian mountain landscapes, mainly through the itinerant grazing of herds of hundreds of goats and sheep. The new IoT technologies applied in this first approach are promising for a new paradigm of this management. We present the results obtained by GNSS devices on herds of goats and sheep in the central mountains of Portugal during the last year's grazing cycle, 2022. The locations of hundreds of daily grazing itineraries resulted in images showing the grazing pressure on the territory. Principal component analysis of these images highlights the primary role of the shepherd in selecting the journey zone and the animals remaining in preferred spots. The sequence of these components seems to analytically translate the articulation of scales inherent to herding processes previously described by several authors. It integrates scales from the broadest of the herder's initial determination of the grazing area to that of the herd's movement to the most detailed of each animal's food preferences at each site. The decisive role of these essential actors - the shepherds - in the management of Iberian rangelands, demonstrated by IoT technologies, should give confidence to policymakers to promote the value chain of extensive, territorially based small ruminant production over those intensive systems that take us away from the goals of sustainable development.
An Adaptive Agent-Based Model for Observing Smoking Cessation Patterns
Authors: Sordo Margarita , Phillips Andrew B.
Published: February 2023

Background
The complex effect of multiple influencing factors in the idiosyncrasies of how people frame a purpose, and the decisions and actions they carry out to reach a goal have a strong impact on repeated-occurrence behaviors, such as smoking cessation, where the perceived benefit of behavioral change may wane in response to difficulties or setbacks.
Purpose
We applied a modeling cycle methodology to implement a knowledge-based ABM to assess the impact of individual health preferences, and societal factors on modifiable behaviors to identify time-related opportunities for non-pharmaceutical interventions to sustain the desired behavioral changes.
Methods
We gathered and encoded information about patient beliefs, preferences, and societal factors as simple rules to roughly represent patient behaviors. Through ABM simulations we looked at idiosyncratic patterns stemming from the complex effect of multiple influencing factors.
Results
Marked smoking/non-smoking fluctuations of women vs. slower, steadier decline in smoking men highlight the complex effect of multiple influencing factors in the idiosyncrasies of how people frame a purpose, and the decisions and actions they carry out to reach a goal. Unintentional patterns of segregation underline the impact surrounding neighbors’ have on an agent’s behavior, blurring the line between individual motivation and collective influence, leading agents to align with the surrounding majority.
Conclusions
ABMs provide insights on the impact multi-factorial, dynamic individual behaviors, and societal factors have on repeated-occurrence modifiable behaviors, e.g., smoking cessation, and pinpoint opportune educational and motivational adjuvant interventions to counteract negative, more ingrained behaviors, and external factors to improve compliance and success.
Experiments Showing Incompleteness of Wave Theory of Light
Authors: Peng Hui
Published: February 2023

Young’s double slit experiments revived the wave theory of light. The standard interpretation is that the light behaves as waves before and after passing through the double slit. Feynman called the double slit experiment the only mystery in quantum mechanics. By placing a convex lens at different positions, we have shown: (1) Near the diaphragm, light behaves as photons and produces a non-interference pattern; near the screen, the photons produce an interference pattern; (2) The non-interference pattern evolves to the orthogonal interference pattern gradually in the same experiment; (3) The convex lens stops the further evolution. It is heuristic for study the nature of light by showing all of three different kinds of patterns on the screen simultaneously. For this purpose, in this article, we setup three paths. The light is divided into three portions, each portion propagates along one path. Then inserting three lenses to different Zones of different paths. Experiments show that two non-interference patterns and interference pattern simultaneously emerge on the same screen.
A healthier microbiome helps transgenic maize to defend herbicide toxicity
Authors: Dai Zhongmin , Chu Zhenjiang , Tao Mingzhu , Yu Zeyu , Tao Yimin , Feng Xuping , He Yong , Chen Huaihai , Xu Jianming
Published: February 2023

Background
Transgenic glyphosate-resistant maize has emerged as a way to expand the use of glyphosate for weed control. Studying the microbiome in transgenic plant and rhizosphere soil is vital for understanding the glyphosate-resistant mechanism and optimizing the transgenic design of crops.
Results
In our study, the transgenic modification did not affect the initial bacterial community in the leaf, stem, root of maize, but promoted a healthier microbiome in the rhizosphere soil. After glyphosate stimulation, the transgenic maize recruited more beneficial bacteria to regulate biocontrol, N fixation and P solubilization in both plant tissues and the rhizosphere soil than non-transgenic maize. Notably, the re-inoculation of differential Bacillus from transgenic maize into the leaf of glyphosate-sensitive maize resulted in an enhanced photosynthetic capacity in response to glyphosate, demonstrating the vital role of unique Bacillus for glyphosate resistance.
Conclusion
Our study provides important evidence of transgenic maize tolerance to herbicides from a microbial ecology perspective.
Light and bias-induced room temperature negative differential conductance in Ni-doped ZnO/p-Si Schottky photodiodes for quantum optical applications
Authors: Ocaya Richard O. , Orman Yusuf , Al-Sehemi Abdullah G. , Dere Aysegul , Al-Ghamdi Ahmed A. , Yakuphanoglu Fahrettin
Published: February 2023

We present evidence for the existence of bias and illumination-driven negative differential conductance (NDC) in Ni-doped aluminium/p-Silicon Schottky diodes. We suggest the Ridley–Watkins–Hilsum (RWH) mechanism as a possible explanation of the origin of this NDC. The NDC is dependent on the bias, doping level, and illumination. The dark currents do not show NDC regions, implying that it is a bias and illumination-dependent effect. We use surface plots to visually enhance the parametric trends in the output data. The resultant devices show excellent performance characteristics in both the photoconductive and the photovoltaic modes. The recently reported series resistance compensated method was applied to the I-V characteristics to extract the parameters of the diodes. The results show that Ni doping achieves NDC in reverse bias, between -1.5V to -0.5V, but only at certain doping levels in forward bias. The open circuit voltages of the devices in solar cell mode ranged from 0.03V to 0.6V.
Zur Stofflichkeit digitaler Medien
Authors: Hoiß Christian
Published: February 2023

Stoffe, die in digitalen Geräten und der Digitalisierung zugrunde liegenden technischen Infrastruktur enthalten sind, machen digitales Lernen letztlich erst möglich. Zugleich entziehen sie sich weitgehend unserer Wahrnehmung. Auch in der mediendidaktischen Forschung ist die Auseinandersetzung mit ihnen ein blinder Fleck. Nach einer Analyse des gegenwärtigen Diskurses um digitale Bildung erörtert der Beitrag, dass die gegenwärtig vorherrschende Vorstellung von Digitalisierung konzeptuell auf einer Metapher beruht, die Digitalisierung als von aussen über unsere Gesellschaft hereinbrechenden Prozess begreift, dem man mehr oder weniger machtlos gegenübersteht und auf den auch im Bildungsbereich immer nur reagiert wird, dem gegenüber aber nicht prospektiv agiert wird. Dieses Denkmuster wirkt sich auf die allgemeine Wahrnehmung sowie auf pädagogisch-didaktische Schwerpunktsetzungen im Bereich digitaler Bildung aus, etwa indem Digitalisierung nicht als ressourcenverbrauchender globaler Konsumprozess verstanden wird. Die mangelnde Beschäftigung mit den technisch-materiellen Grundlagen digitalen Lebens und digitaler Bildung kann als kollektive Wahrnehmungspräferenz verstanden werden. In der Folge dringen Umweltschäden und soziale Ungerechtigkeiten, die durch die Produktion der digitalen Geräte und Schaffung der digitalen Infrastrukturen vor allem im Globalen Süden herbeigeführt werden, nicht in das gesellschaftliche Bewusstsein im Globalen Norden vor und bleiben auch im Bildungsbereich systematisch ausgeblendet. Anhand konkreter Beispiele wird gezeigt, dass mediendidaktisches Arbeiten Reflexionsprozesse über die materiellen Grundlagen digitalen Seins und ihre globalen Implikationen anregen kann, und wie dadurch eine Erweiterung des mediendidaktischen Verantwortungsbereichs um sozialökologische Aspekte erfolgen kann.
Sustainable Sourcing of Raw Materials for Construction: From the Earth to the Moon and Beyond
Authors: Valentini Luca , Moore Kathryn R. , Bediako Mark
Published: February 2023

Each year, nearly 40 billion tonnes of raw materials extracted from the Earth’s crust feed into the construction industry. The associated material flows dramatically contribute to anthropogenic CO2 emissions. Therefore, more sustainable supply chains must be envisaged based on the use of locally available resources and the principles of circular economy. Drawing inspiration from vernacular architecture, innovative solutions for green construction based on sustainable exploitation of local resources can be posited. This strategy has also inspired the proposed practice of in situ resource utilization on planetary bodies such as the Moon and Mars.
Penerapan Metode K-Nearest Neighbor untuk Mengklasifikasi Penyebaran Kasus Demam Berdarah Dengue (DBD) di Kabupaten Maluku Tenggara
Authors: Matdoan Muhammad Yahya
Published: February 2023

Demam Berdarah Dengue (DBD) merupakan penyakit yang disebabkan oleh virus dengue yang ditularkan melalui gigitan nyamuk Aedes Aegypti dan masuk ke peredaran darah manusia. Penyakit ini merupakan penyakit berbahaya yang sering menimbulkan kekhawatiran masyarakat karena perjalanan penyakitnya cepat dan dapat meyebabkan kematian dalam waktu singkat. Oleh karena itu, perlu dilakukan kajian tentang penyebarannya sehingga dapat diambil tindakan cepat dalam mencegah kasus tersebut, Salah satu metode yang dapat digunakan yaitu metode K-Nearest Neighbor (KNN). K-NN merupakan suatu bentuk model pendukung keputusan yang dapat megklasifikasikan data berdasarkan jarak terdekat. Data yang digunakan dalam penelitian ini bersumber dari BPS Kabupaten Maluku Tenggara tahun 2021. Penelitian ini diperoleh hasil bahwa terdapat 2 kelompok penyebaran DBD di Kabupaten Maluku Tenggara yaitu Kecamatan yang berpotensi DBD tinggi yaitu terdiri dari Kecamatan Kei Besar, Kecamatan Kei Kecil dan Kecamatan Kei Besar Selatan Barat. Selanjutnya kecamatan yang berpotensi penyebaran DBD rendah yaitu Kecamatan Kei Besar Utara Barat, Kecamatan Kei Besar Selatan, Kecamatan Kei Besar Timur Selatan, Kecamatan Kei Besar Utara Timur, Kecamatan Hoat Sorbay, Kecamatan Kei Kecil Barat, Kecamatan Kei Kecil Timur dan Kecamatan Manyeuw.Kata Kunci: Demam Berdarah Dengue, K-Nearest Neighbor, Maluku Tenggara.
MORPHOLOGICAL PRODUCTIVITY OF COMPOUND NOUNS IN ENGLISH AT THE LEVEL OF WORD-FORMATION RULES
Authors: M. Žarković Mccray Maja , R. Kujundžić Maja
Published: February 2023

This paper tries to present morphological productivity of compound nouns in a corpus comprised of news, literary, academic and TV registers using an onomasiological approach, namely, the productivity at the level of word-formation rules. The productivity at the aforementioned level is the union of the productivity at the level of word-formation types and morphological types. By using manual, descriptive, analytic and statistical methods, we came to 571 examples of compound nouns that fell into 10 diﬀerent conceptual categories (Agent, Action, Result, Object, Location, Instrument, Substance, Time, Quantity, State), i.e. clusters. Each cluster oﬀered pieces of information on the interaction of diﬀerent concepts within diﬀerent word-formation types together with the morphological aspect through diﬀerent morphological types, which was the aim of the paper. The results proved our initial hypothesis that the interaction of diﬀerent elements is of the utmost significance for better understanding of compounding. The interaction of two concepts dominated all clusters while the combination of two stems, especially two nouns, dominated morphological types.
BERTA BOJETU BOETA’S DYSTOPIAN VISIONS
Authors: Prosenc Irena
Published: February 2023

This article examines two novels by the Slovene writer Berta Bojetu Boeta: Filio is Not at Home (Filio ni doma) and The House of Birds (Ptičja hiša), both published in the 1990’s. The two works depict dystopian societies focused on repression and aimed at generating systematic alienation. The plots are set in remote and isolated places (an island, a mountain, a prison, a brothel) whose inhabitants are enslaved and subjected to violence which mainly aﬀects women. The denial of freedom that characterises these societies is one of the fundamental aspects of dystopian fiction. Despite the extreme limitation of their possibilities, the characters narrated by Bojetu find ways of resisting repression through painting, reading and the creation of human bonds, thus managing to escape from dystopian environments and keep their humanity alive.
ÒGBÓJÚ ỌDẸ NÍNÚ IGBÓ IRÚNMỌLẸ̀ (THE FOREST OF A THOUSAND DAEMONS: A HUNTER’S SAGA) AND LÁNGBÒDÓ (THE INDESCRIBABLE MOUNT): PERFORMING CULTURE IN AFRICA
Authors: Balogun Shola , John Macaulay Abiodun
Published: February 2023

The study of theatre culture in Africa provides a significant background to reassess the emphasis on orthodox ideologies and inﬂuence of European aesthetics on the development of African theatre. The tradition of locating the worldview of dramatic characters within a culture which the audience within the culture can emphathise with is universal. And in most instances it is the misinformation about what is stylistically diﬀerent across cultures that is instrumental in isolating non-Western people's experiences. Thus the contextualisation of D. O. Fágúnwà’s novel, Ògbójú Ọdẹ Nínú Igbó Irúnmọlẹ̀, translated from the Yorùbá as The Forest of a Thousand Daemons: A Hunters Saga by the Nobel Prize winner Wole Soyinka, and Lángbòdó, the stage adaption whose title, Lángbòdó (The Indescribable Mount), is based on the wild locale at the heart of the hunter's adventure in Fágúnwà's novel by Wálé Ògúnyẹmí, within the system of Aláárìnjó the indigenous Yorùbá Travelling Theatre in West Africa, asserts culture as a performance space. The approach to understanding the concept of a theatre is to understand the art form which is characteristic of the culture. In the dramatic narrative of the hunter-narrator on a mission to the distant Mount Lángbòdó, Fágúnwà and Ògúnyẹ́mí capture the functional dimensions of indigenous people's theatres distinctive from European realities. This paper is an attempt to emphasise the importance of revisiting the definitions and developments of theatre along the backgrounds of indigenous cultures and theatrical arts such as Aláárìnjó as drawn from the selected works of the two Yorùbá writers.
THE FRONT DOORBELLS IN TAT’JANA TOLSTAJA’S STORIES: THEIR DESIGN AND CULTURAL MEMORY
Authors: Baselica Giulia
Published: February 2023

In some stories by Tatyana Tolstaya, published between 2004 and 2015, of Soviet and post-Soviet setting, the doorbell, in the representation of living contexts, seems to take on a non-secondary significance. Sometimes, it is its aesthetic value to be highlighted; while, in other moments, it is its function to be emphasised. This article aims to investigate the meaning the doorbell acquires in Tolstaya’s narratives, the way it relates, each single time, to the surrounding system of objects, as well as with the main characters of the stories. Although its being a product of modern technology, the doorbell, located on the front door, connects to the threshold, a place steeped in stratified mythical and ancestral values.
LA CONCEPTION DIDACTIQUE DES PROJETS DANS LA MÉTHODE #LA CLASSE A2
Authors: Mikić Jovica M.
Published: February 2023

Dans cet article, nous examinons la conception des projets dans la méthode de FLE pour adolescents, ♯La Classe A2. Après avoir établi huit critères d’analyse, nous considérons les trois aspects suivants de l’objet de la recherche : la prise de positions, de la part des auteurs, concernant le rôle des projets dans la méthode ; la distribution des rubriques destinées aux projets, ainsi que leur contenu, dans le livre de l’élève et dans le guide pédagogique ; l’élaboration détaillée de la démarche méthodologique dans le cadre d’un projet particulier. Une attention particulière portée à la conception des projets est confirmée par les éléments suivants : la référence à des documents didactiques ; la formulation des titres des unités didactiques et des leçons ; la présentation du projet sur la page d’ouverture de l’unité didactique ; les propositions pour sa réalisation par étapes dans les quatre leçons ; les conseils et explications supplémentaires dans le livre du professeur. Dans cette méthode, nous découvrons la concrétisation cohérente des principes relatifs à la perspective actionnelle, selon laquelle les activités langagières prennent leur pleine signification dans la réalisation de tâches contextualisées et authentiques. L’utilisation de cette méthode dans l’enseignement institutionnel du FLE pourrait contribuer à l’innovation du processus de formation, mais en même temps elle nécessiterait le changement partiel de l’approche communicative : la mise en question des objectifs établis, la modification de manières d’enchaîner les activités didactiques, la recherche des modalités d’évaluation pertinentes.
UN APERÇU DES DÉFIS DE LA TRADUCTION JURIDIQUE: À LA RECHERCHE DES SOLUTIONS
Authors: Vušović Olivera B.
Published: February 2023

L’objectif de cet article est d’établir un aperçu des principales particularités et difficultés que l’on trouve dans le domaine de la traduction juridique, ainsi que d’examiner des solutions possibles. Les considérations introductives portent sur la problématique de la traduction et de l’équivalence en général, ainsi que sur la double dimension de l’équivalence d’un texte juridique et la notion d’équivalent fonctionnel. Les particularités de la traduction juridique sont examinées à travers la combinaison de six éléments : la question de la norme juridique et ses conséquences sur la traduction, la non-concordance des concepts juridiques entre différentes langues, la spécificité et la diversité des langues et des cultures au sein desquelles se construit le droit, la question d’équivalence des effets juridiques, la possibilité de traduire le droit et la variété des domaines, un nouvel aspect propre notamment au droit de l’UE. Finalement, la question de la formation des traducteurs juridiques est abordée dans le contexte du choix entre les compétences en traduction et en droit, ou de préférence, de la fusion des deux.
NEW TRENDS IN ITALIAN LITERATURE: FROM ECOCRITICISM TO MIGRANT LITERATURE
Authors: Mihaljević Nikica N.
Published: February 2023

In the present article the aim is to demonstrate that one of the ways to teach literature today, in the new millennium, when literary studies do not encourage interest among the new generations, could be through its relationship with other sciences, for example, with ecology. Since the 1970's, when ecocriticism was created, in a literary text the idea is to try to analyse the relationship between the individual and nature. Starting from the fact that in nature there are balanced relations, the ecocriticism is trying to overcome the hierarchical order imposed in the society by the secular centralism. The result of this order are the members that are marginalised and oppressed, the victims of the imposition of the concept of the vertical society which implies the dominance of some members over others.

In the analysis the aim is to show that there are some contemporary literary texts that witness the attempt of exclusion of some characters, such as, for example, in the migrant literature in Italy, where the characters-immigrants are frequently discriminated. According to ecocriticism, in order to achieve a sustainable society, it is necessary to overcome these dicriminatory mechanism. Therefore, with this paper we try to find some literary examples in which, by the means of the autobiographical testimony, this attempt of dominance is rejected by the characters and they eventually find the way to integrate into the new society as well as to overcome exclusion and discrimination. In the analysis we examine some of these examples that we find in the literary work of the two contemporary authoresses in Italy: Igiaba Scego, and Laila Wadia.
MUSICAL EKPHRASIS IN THE SERBIAN NOVEL OF THE LATE 20TH – EARLY 21ST CENTURY (THE EXPERIENCE OF A. GATALICA, M. PAVIĆ, G. PETROVIĆ AND G. ĆIRJANIĆ)
Authors: Bilyk Natalia
Published: February 2023

The multifaceted interrelationships of the various media are now considered to be a particular productive area of comparative strategy. The generalised typology among the types of intermedia at the present stage is considered to be the most fruitful and effective, in particular, ekphrasis and intermedia – a particular manifestation of intermedia, the phenomenon of specific expressive mediation of one media in the figurative field of another. Intermediate format, developed by the interaction of different sign systems and the content encoded by them, mainly – literature and other arts with emphasis on the sign and semantic correspondence of comparisons, has significant artistic effectiveness. A way to realise the ekphrasis of the reception as a description of the case is any kind of art in the literary text. At the same time, the preferred determinant of ekphrasis as a description of a work of art in a literary text is suggested to be its relation to a specific work of authorship, although it also assumes the spread of the ekphrasis to similar or non-existent but genre conventional art variants with a pre-eminent inheritance of the corresponding art. In determining the universal common principles of organising such sovereignty of sign systems, positioned in the status of local variants of different discursive practices in the process of their syncretic interaction in the literary dimension, effective for illuminating the raised issue are primarily the tendencies of the extracurricular direction of literary criticism, initiated by Lotman's semiotic concept, initiated by the first concept, the imposition and intersection of semantic spaces capable of generating new meaning. The empirical plan of ekphrasis is vividly and convincingly actualised in the novels of famous Serbian writers A. Gatalica, M. Pavić, G. Petrović, G. Ćirjanić. Innovative creative experience of artists testifies to a special sophistication, content, accuracy of design and diversity and comprehensibility of meaningful potential, which brings the manifestations of the poetics of syncretism of arts to the organisational components of the poetics of novels in general.