bluuebunny/crossref_metadata_2025 huggingface dataset:
3-ARILIDENE-2-OXYNDOLE DERIVATIVESAS MELATONIN ANALOGUES WITH ANTIOXIDANT AND INTRAOCULAR PRESSURE LOWERING PROPERTIES
Authors:   Volgograd State Medical University, Spasov A.A. , Naumenko L.V. ,   Volgograd State Medical University, Yakovlev D.S. ,   Volgograd State Medical University,   Volgograd Medical Scientific Center, Taran A.S. ,   Volgograd State Medical University,   Volgograd Medical Scientific Center, Sokolova E.V. ,   Volgograd State Medical University, Klochkov V.G. ,   Volgograd State Medical University, Borisov A.V. ,   Volgograd State Medical University, Bezsonova E.N. ,   Lomonosov Moscow State University, Efremov A.M. ,   Lomonosov Moscow State University, Lozinskay N.A. ,   Lomonosov Moscow State University, Babkov D.A. ,   Volgograd State Medical University
Published: January 2023

Aim.Glaucoma is a whole group of diseases caused by increased intraocular pressure (IOP), leading to atrophy of the optic nerve and irreversible blindness. Melatonin has a wide range of biological activity, including antioxidant and antiglaucoma, but its use is limited by insufficient stability and duration of action. To search for new, more effective antiglaucoma agents among derivatives of 3-arylidene-2-oxindole, melatonin analogues, a search for quinonoxidoreductase 2 (NQO2) inhibitors was performed, antioxidant activity was determined and the effect of active compounds on intraocular pressure was studied.Materials and methods.The study of inhibitory activity against NQO2 was evaluated kinetically using menadione and N-benzyl-dihydronicotinamide assubstrate and co-substrate, respectively. Antiradical activity was studied for reducing superoxide-dependentluminescence in a reaction medium containing hemoglobin, luminol and hydrogen peroxide using the Infinite M200 PRO microplate reader (Tecan, Austria), as well as for free radical binding tests OH•-, ABTS and DPPH. Cytotoxicity assessment was carried out using a standard MTT test on MCF-7 and HepG2 line cells. Intraocular pressure in laboratory animals was measured using a contactveterinary tonometer Tonovet (Finland).Results.Derivatives of 3-arylidene-2-oxindole have demonstrated significant antioxidant activity. A number of NQO2 inhibitors have also been identified. The most active compound inhibits human NQO2 with an IC50of 0,4 μM. The compound also showed anti-radical activity, binding the superoxide anion to IC50of 6,1 μM, superior to melatonin on both counts, and low cytotoxicity. With topical application of a 0,4% solution, the compound reduced the intraocular pressure of intact rats by (40,9 ± 6,4) %, while not having a systemic hypotensive effect.Conclusion.Derivatives of 3-arylidene-2-oxindole are promising for drug discovery for the treatment of eye diseases associatedwith increased intraocular pressure or oxidative stress, such as glaucoma, uveitis and diabetic retinopathy.
The concept of energy efficiency in industry
Authors:   Ural state University of railway transport (USURT), Koksharov V. A.
Published: January 2023

The work is devoted to the actual problem of efficient use of energy resources in industry. The methodological approach to the assessment of energy-efficient consumption of energy resources at an industrial enterprise is considered; assessment of stakeholders in the implementation of energy policy; strategy for the effective use of energy resources; formation of a system of models for the implementation of strategies for the effective use of energy resources; forecasting of electrical consumption of industrial enterprises within the framework of sustainable production organization; conceptual approach to the model for assessing the efficiency of the closed-cycle economy of an industrial enterprise. It is recommended to students of energy and economic specialties of universities, as well as managers and specialists of industrial enterprises and energy companies.
2U2i AND WBL-BASED PROGRAMS STUDENT-CENTERED LEARNING EFFICACY IN MALAYSIAN HIGHER EDUCATION
Authors:   Master of Education, Institutional Audit Division, Malaysian Qualifications Agency, MQA, Cyberjaya, Malaysia, Ramli Suhana Binti , Omar Farkhana Binti ,   Master in Law, Legal Unit, Malaysian Qualifications Agency, MQA, Cyberjaya, Malaysia, Dolah Jasni Bin ,   Ts., Doctorate in Instructional Multimedia, School of The Arts, Malaysian Science University (USM), Penang, Malaysia, Yasin Sarifah Noor Azian Binti Syed ,   Bachelor of Computer Science (Software Engineering), Human Resources Department, Malaysian Qualifications Agency, MQA, Cyberjaya, Malaysia, Jusof Muhammad Jafni Bin ,   Master of Art, Freelancer, Cyberjaya, Malaysia
Published: January 2023

The Malaysian education system must adapt to the 21st-century paradigm change to produce quality graduates who are holistic, balanced, entrepreneurially ready, bright, skilled, and knowledgeable. Student-centered learning (SCL), a teaching-and-learning (TnL) method, is being adopted in the system to develop students' inclinations and higher thinking capacity, revealing individuals' talents in a certain sector meanwhile, 2U2i and work-based learning (WBL) study modes were established to lessen students' reliance on traditional learning by emphasizing particular industrial in-field learning and continuous learning. The purpose of this study is to verify the reliability and validity of the instrument that will be used to determine the efficacy of SCL in 2U2i and WBL programs among participating local higher education providers (HEP) aside from confirming the existence of SCL elements within the programs. The initial data collection procedure involved questionnaires with students as well as industry players with whom the students are currently affiliated. The results suggest that the instrument used is viable and easily understandable by respondents. However, it is insufficient to formulate a truly effective instrument due to the small sample size and differences in the implementation of 2U2i and WBL programs, suggesting a complete data collection involving all related parties in future studies.
BUZZER: POLITIC’S INTEREST AND MASLAHAH
Authors: Amanatus Sholihah
Published: January 2023

Abstract

Indonesia’s political tensions are heating up lately. It has been showed by some commotions happen after populism and political identity was buzzed since general election on 2019. These commotions were escalated when the political elites and parties involved political buzzer within democracy. Some sensitive issues spread by political buzzer through campaign narrations and it causes society segmented into two parts: “Cebong” and “Kampret”.  They have been attacking each other both in social media and in real life; or both psychological and physical. It keeps happen now. This paper wants to learn why are buzzers appear together with political events include general election, and how is buzzers in Islamic perspective. This is descriptive paper with literature review’s method that conducting some doc5uments, journals, news relating with problem research. Then the result shows that buzzers appear in political events because it is one of political instruments who are needed in digital era massively. In Islamic perspective, buzzers gave maslahah (positive impact) to the democracy. But in another hand, their activities on social media such as produces a hoax, etc. categorized as fitnah, ghibah and namimah that is gave madharat too. Then the ways to handle some negative impacts of buzzers in social media are optimyze the roles and synergies of all parties from the government, political elites, parties, and educate society to minimize political buzzer in spreading hate speech, black campaign, and hoax. So as to create healthy political participation both in social media and in social life.

Keywords: buzzer, political interest, and maslahah.
Pegada Hídrica Virtual das exportações de Mato Grosso versus os repasses federais Lei Kandir e FEX: uma análise do período de 2013 a 2017
Authors: Socoloski André , Ribeiro Magno Alves , Grzebieluckas Cleci , Santos Josiane Silva Costa dos
Published: January 2023

Indispensável para a produção de todos os bens e serviços, a água é utilizada de forma gratuita, principalmente para a produção agropecuária, e grande parte dessa produção é exportada, incluindo a água, denominada de água virtual. Neste contexto, o objetivo do estudo é comparar a Pegada Hídrica Virtual das exportações mato-grossenses com os repasses estabelecidos pela Lei Kandir e pelo Auxílio Financeiro para Fomento das Exportações (FEX)  recebidos pelo Estado de Mato Grosso e seus municípios. O estudo é de natureza descritiva, bibliográfica, com abordagem quantitativa, e usou como fonte dados secundários. Os dados das exportações foram obtidos do site oficial do Ministério da Indústria, Comércio Exterior e Serviços (MDIC), pela “Balança comercial brasileira: Unidades da Federação”. A Pegada Hídrica (PH) foi com base na literatura existente, calculada para cada produto, agregando-a por ano e produto. A precificação da água teve como base a cobrança pelo uso dos recursos hídricos disponibilizados pela Agência Nacional de Águas (ANA). Os dados dos repasses federais referentes à Lei Kandir e ao Auxílio Financeiro para Fomento das Exportações (FEX) foram obtidos do site oficial da Secretaria do Tesouro Nacional (STN). Considerando as métricas, a Pegada Hídrica Virtual, no período de 2013/2017, foi de R$ 4.141.608.401,68, enquanto os valores repassados pela União para a compensação foi de R$ 2.192.403.831,16; ou seja, uma diferença no montante de R$ 1.949.204.570,53, ficando, assim, um deficit ambiental, pois os repasses recebidos são menores que a Pegada Hídrica Virtual.
Estratégias municipais e serviços públicos com tecnologia da informação no contexto de cidade digital estratégica: caso de Goiânia, GO
Authors: Júnior Roosevelt Leão , Rezende Denis Alcides , Baú Daniele , Almeida Giovana Goretti Feijó de
Published: January 2023

As transformações econômicas, sociais e tecnológicas pelas quais passam a cidades possuem um denominador comum que leva à pressão para que ela sirva à população de forma mais efetiva, promovendo seu desenvolvimento local. O objetivo é analisar estratégias municipais e serviços públicos digitais e suas relações com cidade digital estratégica em Goiânia, GO, Brasil. A metodologia da pesquisa enfatizou um estudo de caso com um protocolo de 6 variáveis. Os resultados auferidos evidenciaram o uso diversificado de temáticas municipais, tanto na disposição das estratégias municipais quanto na oferta de serviços públicos com tecnologia da informação. Esses serviços, quando inseridos em um processo efetivo, levam à qualidade de vida do cidadão, conectando-se com a cidade digital estratégica. Para os cidadãos, isso amplia o debate sobre qualidade de vida urbana e, para os gestores públicos, apresenta discussões sobre o meio urbano na perspectiva do desenvolvimento local. A conclusão reitera que os serviços públicos com tecnologia da informação alinhados às estratégias municipais fazem parte de um processo de inovação em favor da qualidade de vida dos cidadãos e no desenvolvimento local. Constituem-se em um caminho para entrega de serviços públicos com tecnologia da informação de qualidade à população, por meio de projetos municipais, como o de cidade digital estratégica.
Impactos das mudanças climáticas na produção agrícola e medidas de adaptação sob a percepção de atores e produtores rurais de Nova Friburgo, RJ
Authors: Oliveira Samira França , Prado Rachel Bardy , Monteiro Joyce Maria Guimarães
Published: January 2023

A agricultura é um dos setores mais vulneráveis às mudanças climáticas, devido à dependência intrínseca dos fatores climáticos e recursos naturais, principalmente os agricultores familiares. Os impactos das mudanças climáticas podem ser minimizados por meio de medidas de adaptação adotadas, que devem ser adequadas ao contexto da região. O objetivo é identificar a percepção dos produtores e atores rurais sobre os impactos das mudanças climáticas na produção agrícola, bem como as medidas de adaptação adotadas, analisando também a relação entre a percepção dos produtores e atores rurais e os dados climáticos e da produção agrícola do município de Nova Friburgo, Rio de Janeiro. Os dados resultam de entrevistas aplicadas aos produtores e atores rurais de Nova Friburgo e em base de dados secundários (produção agrícola municipal e dados históricos meteorológicos); eles foram relacionados para identificar a percepção dos entrevistados em relação aos impactos das mudanças climáticas e as medidas de adaptação adotadas. A maioria dos atores rurais e dos produtores convencionais e orgânicos percebe os impactos das mudanças climáticas na produção agrícola; entretanto, não identificou com precisão o ano em que ocorreu o impacto. Predominam as adaptações adotadas do tipo incrementais e coincidem com o que é descrito na literatura científica.
Empreendimentos solidários e sua capacidade de promover a agricultura familiar
Authors: Rêgo Amanda Barbosa , Godoi Emiliano Lobo de
Published: January 2023

A agricultura familiar detém grande relevância produtiva, econômica, social e cultural no país, mas ainda conta com grandes dificuldades de se inserir no mercado capitalista altamente competitivo. A economia solidária visa ser um contraponto a esse sistema econômico vigente, pois se baseia no desenvolvimento econômico amparado na cooperação entre as pessoas, na autogestão dos empreendimentos e na busca por uma forma de vida melhor de seus participantes. O objetivo do estudo foi trazer algumas características da economia solidária no Brasil e como ela pode ser instrumento impulsionador e de apoio ao progresso da agricultura familiar. Realizou-se pesquisa bibliográfica e documental, com coleta de informações em renomadas bases de dados nacionais, como o Instituto Brasileiro de Geografia e Estatística (IBGE) e o Sistema de Informação em Economia Solidária (SIES). Percebeu-se que a agricultura familiar escoa seus produtos principalmente pela venda direta aos consumidores, que seus mercados são locais e a falta de capital de giro é sua dificuldade prevalecente.
Gerenciamento de resíduos de serviço de saúde pelos cirurgiões-dentistas no Planalto Serrano Catarinense
Authors: Koch Barbara , Siegloch Ana Emilia , Agostinetto Lenita
Published: January 2023

O objetivo foi avaliar o gerenciamento de resíduos de serviços de saúde por cirurgiões-dentistas que atuam no setor público e no setor privado. O estudo foi de campo, quantitativo e descritivo, com 48 profissionais do setor público e privado. A coleta de dados ocorreu entre os meses de dezembro de 2020 e março de 2021, pela aplicação de questionário com 40 questões, o qual foi divulgado nas redes sociais e aplicado via Formulários Google, após aprovação pelo Comitê de Ética em Pesquisa. Os dados foram submetidos à estatística descritiva e ao teste de associação entre as variáveis (qui-quadrado). Observou-se que 29,17% dos participantes não têm conhecimento sobre o descarte de Resíduos de Serviço de Saúde (RSS), 39,58% desconhecem os procedimentos de descarte sobre medicamentos vencidos e suas sobras; 47,92% desconhecem o Plano de Gerenciamento de Resíduos de Serviço de Saúde (PGRSS); 45,83% desconhecem há quanto tempo este foi implementado; e 77,08% afirmaram falta de capacitação sobre gerenciamento de RSS, sendo a principal dificuldade apontada para o adequado gerenciamento de resíduos. É imprescindível fomentar práticas de educação permanente que contribuam na formação e na atuação profissional sobre gestão dos RSS e instigar a implementação e o funcionamento do plano municipal de gestão de resíduos.
Forgotten “Primum Non Nocere” and Increased Mortality after Covid-19 Vaccination
Authors: Šorli Srecko , Makovec Tomaz
Published: January 2023

Background The main reason for the worldwide massive covid vaccination in 2021 was to reduce the high mortality caused by the Covid-19 virus in 2020. It is time that in 2022 a rigorous analysis is done of the effectiveness of this massive vaccination. Methods In statistics, we have an accurate methodology to measure the impact of massive vaccination on public health. The mathematical relation between vaccinated/alive groups will be repeated between vaccinated/dead groups with high statistical certainty. This occurs because we are dealing with big numbers. Results Calculations were done for five periods of four weeks: weeks 35-38 (2021), weeks 39-42 (2021), weeks 43-46 (2031), weeks 47-50 (2021), and weeks 51(2021)-2(2022). Obtained results are confirming that the mortality of the vaccinated infected groups is higher on average by 14.5% than the mortality of non-vaccinated infected groups. Conclusions Results are suggesting the extension of the statistic between the vaccinated/alive group and the vaccinated/dead group for different age groups. These statistics will have higher statistical significance because of the elimination of the Simpson effect. Calculating the exact impact of covid-19 vaccination on the mortality rate is the necessary step to satisfy the first principle of medicine: “Primum non nocere”.
Rise and Fall of Caribbean Mangroves
Authors: Rull Valenti
Published: January 2023

Mangrove forests, which are essential for the maintenance of terrestrial and marine biodiversity in tropical coasts and constitute the main blue-carbon ecosystems for the mitigation of global warming, are among the world’s most threatened ecosystems. Mangrove conservation can greatly benefit from paleoecological and evolutionary studies, as past analogs documenting the responses of these ecosystems to environmental drivers such as climate change, sea level shifts and anthropogenic pressure. A database (CARMA) encompassing nearly all studies on mangroves from the Caribbean region, one of the main mangrove hotspots, and their response to past environmental shifts has recently been assembled and analyzed. The dataset contains over 140 sites and ranges from the Late Cretaceous to the present. The Caribbean was the cradle of Neotropical mangroves, where they emerged in the Middle Eocene (~50 million years ago; Ma). A major evolutionary turnover occurred in the Eocene/Oligocene transition (34 Ma) that set the bases for the shaping of modern-like mangroves. However, the diversification of these communities leading to their extant composition did not occur until the Pliocene (~5 Ma). The Pleistocene (the last 2.6 Ma) glacial-interglacial cycles caused spatial and compositional reorganizations with no further evolution. Human pressure on Caribbean mangroves increased in the Middle Holocene (~6000 years ago), when pre-Columbian societies began to clear these forests for cultivation. In the last decades, deforestation has reduced the Caribbean mangrove cover by one third and it has been estimated that, if urgent and effective conservation actions are not undertaken, these 50 million-year-old ecosystems might disappear in little more than half a century. A number of specific conservation and restoration applications based on the results of paleoecological and evolutionary studies are suggested.
Stress-inducible SCAN Factors Suppress the Stress Response and Are Biomarkers for Enhanced Prognosis in Cancers
Authors: Eguchi Takanori , Sheta Mona , Calderwood Stuart K
Published: January 2023

The cell stress response is an essential system present in every cell for responding and adapting to extracellular environmental stimulations. A major program for stress response is the heat shock factor (HSF)–heat shock protein (HSP) system that maintains proteostasis in cells and promotes cancer progression. However, less is known about how the cell stress response is regulated by alternative transcription factors. Here, we show that the SCAN domain-containing transcription factors (SCAN-TFs) are involved in repressing the stress response in cancer. SCAND1 and SCAND2 are SCAN-TFs that can hetero-oligomerize with SCAN-zinc finger transcription factors, such as MZF1(ZSCAN6), for accessing DNA and transcriptionally co-repressing target genes. We found that heat stress induced the expression of both SCAND1 and MZF1(ZSCAN6) bound to HSP90 gene promoter regions in prostate cancer cells. SCAND1 and MZF1 blocked the heat shock responsiveness of HSP90 in prostate cancer cells. Gene expression of SCAND2, SCAND1 and MZF1 was negatively correlated with HSP90 expression in patients-derived prostate adenocarcinoma. MZF1 and SCAND2 were more highly expressed in paired normal tissues than in tumor tissues in several cancer types. High expression of SCAND2, SCAND1 and MZF1 correlated with enhanced prognoses of pancreatic cancer and head and neck cancers. Additionally, high expression of SCAND2 was correlated with better prognoses of lung adenocarcinoma and sarcoma. In contrast, high expression of HSP90AA1 correlated with poorer prognoses in several cancer types. These data suggest that the stress-inducible SCAN-TFs can function as a feedback system, suppressing excessive stress response and inhibiting cancers.
Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast
Authors: Takahata Shinya , Murakami Yota
Published: January 2023

DNA is stored in the nucleus of a cell in a folded state; however, only the necessary genetic information is extracted from the required group of genes. The key to extracting genetic information is chromatin ambivalence. Depending on the chromosomal region, chromatin is characterized into low-density "euchromatin" and high-density "heterochromatin", with various factors being involved in its regulation. Here, we focus on chromatin regulation and gene expression by the yeast FACT complex, which functions in both euchromatin and heterochromatin. FACT is known as a histone H2A/H2B chaperone and initially reported as an elongation factor associated with RNA polymerase II. In budding yeast, FACT activates promoter chromatin by interacting with the transcriptional activators SBF/MBF via the regulation of G1/S cell cycle genes. In fission yeast, FACT plays an important role in the formation of higher-order chromatin structures and transcriptional repression by binding to Swi6, an HP1 family protein, at heterochromatin. This FACT property, which refers to the alternate chromatin-regulation depending on the binding partner, is an interesting phenomenon. Further analysis of nucleosome regulation within heterochromatin is expected in future studies.
Development and Evaluation of a Cellular Vehicle-to-Everything Enabled Energy-Efficient Dynamic Routing Application
Authors: Farag Mohamed , Rakha Hesham A.
Published: January 2023

Cellular Vehicle-to-Everything (C-V2X) is a communication technology that supports various safety, mobility, and environmental applications given its higher reliability properties compared to other communication technologies. The performance of these C-V2X-enabled Intelligent Transportation System (ITS) applications is affected by the performance of the C-V2X communication technology (mainly packet loss). Similarly, the performance of the C-V2X communication is dependent on the vehicular traffic density which is affected by the traffic mobility patterns, and vehicle routing strategies. Consequently, it is critical to develop a tool that can simulate, analyze, and evaluate the mutual interactions of the transportation and communication systems at the application level and to the evaluate the benefits of the C-V2X enabled ITS applications. In this paper, we demonstrate the benefits gained when using C-V2X Vehicle-to-Infrastructure (V2I) communication technology in an energy-efficient dynamic routing application. Specifically, we develop a Connected Energy-Efficient Dynamic Routing (C-EEDR) application using C-V2X as a communication medium in an integrated vehicular traffic and communication simulator (INTEGRATION). The results demonstrate that the C-EEDR application achieves fuel savings of up to 16.6% and 14.7% in the IDEAL and C-V2X communication cases, respectively for a peak hour demand on the downtown Los Angeles network considering a 50% level of market penetration of connected vehicles. The results demonstrate that the fuel savings increase with increasing levels of market penetration at lower traffic demand levels (25% and 50% the peak demand). At higher traffic demand levels (75% and 100%) the fuel savings increase with increasing levels of market penetration with maximum benefits at a 50% market penetration rate. Although the communication system is affected by the high density of vehicles at the high traffic demand levels (75% and 100% the peak demand), the C-EEDR application manages to perform reliably producing system-wide fuel consumption savings.The C-EEDR application achieves fuel savings of 15.2% and 11.7% for the IDEAL communication and 14% and 9% for the C-V2X communication at the 75% and 100% market penetration rates, respectively. Finally, the paper demonstrates that the C-V2X communication constraints only affect the performance of the C-EEDR application at the full demand level when the market penetration of connected vehicles exceeds 25%. This degradation, however is minimal (less than a 2.5% reduction in fuel savings).
EFEKTIFITAS E-LEARNING SEBAGAI MEDIA PEMBELAJARAN
Authors: Nurhidayat Diat
Published: January 2023

Penelitian ini  bertujuan untuk melihat sejauh mana peserta didik dan guru dalam menerima e-learning yang berbasis moodle pada SMK Karya Guna dalam proses pembelajaran kedepannya. Penelitian ini menggunakan pendekatan penelitian dan pengembangan (Research and Development)yang bertempat di SMK Karya Guna. Penelitian dilakukan sejak Agustus 2017 hingga Juli 2018. Penelitian ini dilakukan terhadap siswa kelas XI TKJ II yang telah mengikuti pelajaran Praktik Jaringan Komputer dan guru TKJ SMK Karya Guna. Tahapan dari penelitian ini adalah potensi dan masalah yang ada, rancangan produk, pembuatan produk, uji coba produk, revisi produk dan implementasi. Penelitian ini diujikan kepada dosen ahli media, dosen ahli e-learning, guru dan siswa. Hasil pengujian dari ahli media untuk versi 3 mendapatkan nilai presentase 88%, oleh ahli e-learning sebesar 85,71, oleh siswa dan guru (kelompok besar) sebesar 92,26% dan  90%. Berdasarkan hasil uji tersebut, dapat disimpulkan bahwa e-learning berbasis moodle versi ketiga sesuai dan dapat diterima dengan baik untuk diterapkan pada mata pelajaran Praktik Jaringan Komputer.
FORMULASI DAN EVALUASI SEDIAAN KOSMETIK PEWARNA RAMBUT DARI EKSTRAK KULIT BATANG SECANG ( Caesalpinia sappan L)
Authors: Nabilah Fildzah
Published: January 2023

Sediaan kosmetika pewarna rambut pada umumnya menggunakan jenis pewara sintetik yang seringkali menimbulkan reaksi alergi. Melimpah nya hasil tanaman secang (Caesalpinia sappan L) di indonesia membuat adanya penelitian tentang pemanfaatan kulit batang secang sebagai bahan dasar pewarna alami yang dapat dijadikan sebagai alternatif untuk menggantikan pewarna sintetik, selain itu juga untuk meminimalisir efek toksik yang dihasilkan oleh pewarna berbahan kimia. yang dapat digunakan dalam sediaan kosmetika salah satunya adalah sediaan pewarna rambut. Kandungan antosianin yang dapat menghasilkan warna orange hingga merah. Tujuan penelitian ini adalah ntuk mengetahui apakan sediaan pewarna rambut ekstrak kulit batang secang berpengaruh terhadap rambut.pada penelitian ini dibuat 3 jenis formula. F1= konsentrasi ekstrak 20%, F2= konsentrasi ekstrak 25%, F3= konsentrasi ekstrak 25%. Penelitian sediaan ini menghasilkan warna rambut dari merah terang hingga merah gelap. Evaluasi yang dilakukan pada penelitian ini adalah berupa pengujian organoleptik, uji homogenitas sediaan pewarna rambut, pengujian pH, pengujian stabilitas warna terhadap sinar matahari , pengujian stabilitas pencucian dan uji biiologis (uji iritasi). Rambut yang di ujikan di rendam dalam cairan pewarna selama 30 menit lalu dibilas dan dilihat hasil nya. Penelitian ini menunjukan bahwa konsentrasi yang menghasilkan warna terbaik adalah formula 3 yang menghasilkan warna merah terang pada rambut.

 

Kata Kunci : Caesalpinia sappan L. Sediaan pewarna rambut. Antosianin.

         Ekstrak.
FORMULASI DAN EVALUASI SEDIAAN KOSMETIK PEWARNA LIPSTIK DARI EKSTRAK KULIT BATANG SECANG (CAESALPINIA SAPPAN L)
Authors: Nurmala Santi Rafika
Published: January 2023

Abstrak

Latar Belakang: Secang (Caesalpinia Sappan L) termasuk familia Caesalpiniaceae. Warna oren hingga merah tua pada kulit batang secang disebabkan oleh brazilin dalam  antosianin. Antosianin ialah pigmen yang dapat digunakan pada lipstik dan menggantikan pewarna lipstick yang pada umumnya menggunakan pewarna sintetis.

Tujuan: Penelitian ini untuk memformulasikan sediaan pewarna lipstik menggunakan zat warna dari kulit batang secang.

Metode Penelitian: Pembuatan ekstrak kulit batang secang dilakukan dengan metode maserasi selama 1x24jam dalam suhu kamar menggunakan pelarut etanol 70% dengan bantuan rotary evaporator sehingga diperoleh ekstrak kental rendemen 75%. Bahan sediaan lipstik terdiri dari carnauba wax, cera alba, setil alcohol, vaselin, oleum ricini, lanolin, propilen glikol, butil hidroksitoluen, nipagin, dan pewarna dari ekstrak kulit batang secang dengan konsentrasi 14%, 22%, dan 30%. Pengujian sediaan yang dibuat meliputi, uji daya oles, uji homogenitas, uji titik leleh, uji  pH, uji kekuatan dan uji organoleptik.

Hasil: Sediaan lipstik yang dihasilkan memberikan warna merah muda hingga merah tua yang mudah dioleskan. Titik lebur lipstik 64,20C; 61,90C dan 60,60C. Nilai pH sediaan adalah 5; 5,7 dan 6,4. Stabilitas warna, bentuk, dan bau stabil..

Kesimpulan: Pengembangan pembuatan sediaan pewarna lipstik dengan ekstrak kulit batang secang dapat digunakan sebagai pengganti pewarna sintetis.

 

Kata kunci: secang, lipstick, pewarna, zat warna
ADAPTASI BURUNG MERAK BIRU PADA TATA RIAS WAJAH FANTASI UNTUK KARNAVAL
Authors: Elva octaviany
Published: January 2023

Adaptasi burung merak biru pada tata rias wajah fantasi terinspirasi dari burung merak biru. Adaptasi adalah praktik merubah objek menjadi sebuah karya seperti menjadikan objek burung merak biru sebagai riasan wajah fantasi. Tata rias wajah fantasi dikenal menampilkan wujud rekaan dengan mengubah wajah tidak realistik atau merupakan perwujudan khayalan yang dituangkan menjadi krativitas pada wajah manusia. Tata rias wajah fantasi burung merak diambil untuk mengangkat ciri khas dari burung merak biru antara lain, bulunya yang berkilau, ekornya yang unik dan warnanya yang indah. Pada hasil riasan ini dilengkapi dengan busana dan aksesoris sehingga menjadi kesatuan yang utuh untuk acara karnaval. Keindahan burung merak biru khususnya pada bagian motif bulu burung merak biru menjadikan inspirasi untuk mewujudkan burung merak biru menjadi tata rias wajah fantasi. Warna biru yang menjadi aksen pada tata rias wajah fantasi harus terlihat dalam penggunaan eyeshadow pada wajah dan penggunaan aksesoris milineris yang menunjang sehingga riasan dan busana memiliki satu kesatuan yang menghasilkan keindahan saat melihatnya.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS PREZI PADA SUB KOMPETENSI PENGERITINGAN DESAIN
Authors: PRATIWI ALVIANA CATUR
Published: January 2023

Media pembelajaran berbasis prezi pada materi pengeritingan desain diharapkan dapat memberikan inovasi pengembangan media pembelajaran dalam proses belajar yang lebih inovatif dan kreatif. Penelitian ini bertujuan (1) Mendeskripsikan prosedur perancangan media pembelajaran berbasis prezi dalam materi pengeritingan desain. (2) Mendeskripsikan kelayakan media pembelajaran berbasis prezi dalam materi pengeritingan desain. Jenis penelitian ini adalah R&D (Research and Development) dengan metode pengumpulan data menggunakan angket penilaian media melalui google form dari 35 observer. Hasil penelitian menunjukkan kelayakan dinyatakan sangat layak untuk digunakan dengan hasil persentase sebesar 85 %. Daya tarik media dapat dikatakan sangat menarik dengan hasil persentase sebesar 82,14%. Kesesuaian media dinyatakan sangat sesuai dengan hasil persentase sebesar 83,57%. Kualitas media dinyatakan kualitas baik memperoleh hasil persentase sebesar 80,71%. Kreatifitas media dinyatakan sangat kreatif dengan hasil persentase sebesar 84,28%. Berdasarkan hasil tersebut, maka penelitian ini mengahasilkan media berbasis prezi yang layak dan telah disesuaikan dengan mata pelajaran pengeritingan desain.

Kata Kunci : Pengembangan media, prezi, pengeritingan desain.
PERSEPSI PENATA RIAS TERHADAP PENGGUNAAN TEKNIK AIRBRUSH DALAM TATA RIAS WAJAH PENGANTIN
Authors: Korn Johanna febriza
Published: January 2023

Penelitian ini bertujuan untuk mengetahui persepsi penata rias terhadap penggunaan teknik airbrush dalam tata rias wajah pengantin. Penelitian ini menggunakan metode kualitatif. Pengumpulan data melalui kuisioner pada awal penelitian dan wawancara pada akhir penelitian. Data dianalisis melalui tahap penyajian data, reduksi data dan verifikasi data lalu diuji kredibilitasnya menggunakan triangulasi sumber. Pertanyaan yang ditanyakan kepada 5 informan yang berprofesi sebagai penata rias pengantin yang menggunakan teknik airbrush meliputi latar belakang pendidikan, pengetahuan tentang teknik airbrush, pengetahuan teantang tata rias wajah pengantin dan dampak penggunaan teknik airbrush dalam tata rias wajah pengantin. Hasil penelitian menunjukkan bahwa: (1)Penggunaan teknik airbrush dapat menghasilkan riasan pada wajah pengantin yang lebih tahan lama, tekstur riasan yang halus, serta dimensi gradasi warna yang membaur. (2)Teknik airbrush dapat diaplikasikan pada beberapa jenis kosmetik dalam proses tata rias, diantaranya dapat diaplikasikan untuk foundation, contour, dan blush on. Selain itu, digunakan pula untuk pelapis dari hasil riasan yang menggunakan teknik konvensional. (3)Penggunaan teknik airbrush pada tata rias wajah pengantin dapat meningkatkan kemampuan, performa, serta nilai eksistensi penata rias karena memiliki kemampuan yang tidak dimiliki oleh penata rias wajah pengantin lainnya secara umum. (4)Teknik airbrush merupakan salah satu teknik dalam merias wajah, terlihat seperti mudah akan tetapi saat digunakan sulit. Maka untuk dapat menggunakan teknik airbrush pada tata rias wajah pengantin harus memiliki keahlian tersendiri agar dapat menghasilkan riasan yang maksimal. (5)Terdapat hambatan dalam penggunaan alat airbrush yaitu lubang pena airbrush sering tersumbat sisa kosmetik yang mengering. Maka dari itu, penata rias yang menggunakan airbrush diharuskan untuk melakukan perawatan setiap komponen alat airbrush agar tetap berfungsi secara baik.
ANALISIS PENGETAHUAN TATA RIAS WAJAH SEHARI-HARI DAN PERILAKU PENGGUNAAN KOSMETIKA
Authors: Gautama Chika , Ambarwati Neneng Siti Silfi
Published: January 2023

CHIKA ERFIANDI GAUTAMA. Analisis Pengetahuan Tata Rias Wajah Sehari-hari dan Perilaku Penggunaan Kosmetika (Studi pada PNS Wanita di Kementriaan Pendidikan dan Kebudayaan). Jakarta. Program Studi Diploma Tiga Tata Rias, Fakultas Teknik, Universitas Negri Jakarta, 2020.

Penelitian ini bertujuan untuk mendeskripsikan mengenai gambaran pengetahuan tata rias wajah dan perilaku penggunaan kosmetika di kalangan Pegawai Negeri Sipil (PNS) wanita di KEMENDIKBUD. Objek penelitian ini adalah Pegawai Negeri Sipil (PNS) yaitu sebanyak 25 orang. Penelitian ini dibuat menggunakan metode deskriptif kuantitatif dengan menyebar kuesioner kepada Pegawai Negeri Sipil (PNS) wanita yang bekerja di KEMENDIKBUD. Berdasarkan kajian teoritis dan pengumpulan data yang dilakukan dalam penelitian ini menghasilkan nilai pengetahuan tata rias sebesar 92.5% dan perilaku penggunaan kosmetika sebesar 86.04%. Maka dapat disimpulkan bahwa pengetahuan tata rias serta perilaku penggunaan kosmetika di kalangan PNS wanita KEMENDIKBUD termasuk dalam kategori sangat baik. Hasil ini dapat diperoleh karena didukung oleh faktor-faktor seperti faktor pendidikan, faktor pekerjaan, dan faktor pengalaman.
PEMBUATAN VIDEO TUTORIAL RIASAN MATA DENGAN TEKNIK AEGYO-SAL PADA PENGANTIN INTERNASIONAL
Authors: Sri irtawidjajanti  , Kanisa Lutfiah Azahra
Published: January 2023

Perkembangan teknik makeup di era yang modern semakin beragam salah satunya tata rias Korea. Salah satu teknik unik pada tata rias Korea yaitu terdapat pada riasan matanya yang menonjolkan kantung mata sehingga membuat riasan mata terlihat lebih terbuka serta bersinar. Riasan mata Korea ini disebut juga dengan istilah aegyo-sal. Penelitian ini bertujuan untuk meningkatkan hasil belajar serta ketertarikan peserta didik terhadap riasan mata dengan teknik aegyo-sal pada mata kuliah Pengantin Internasional serta menjadi media alternatif proses pembelajaran pada program studi Tata Rias di Universitas Negeri Jakarta. Penelitian ini menggunakan metode RnD (Research and Development) yang dimana akan menghasilkan sebuah produk tertentu dan diuji keefektifan produk tersebut. Proses didalam pembuatan produk berupa video ini terdiri dari proses pra produksi, produksi, pasca produksi. Hasil pembuatan video ini memenuhi kriteria validasi dengan hasil yang didapat oleh ahli materi adalah 76%, oleh ahli media 100% dan oleh ahli profesi 93%. Dapat disimpulkan bahwa video tersebut Sangat Layak untuk digunakan sebagai media alternatif didalam pembelajaran pada mata kuliah Pengantin Internasional pada Program Studi Tata Rias, serta dapat bermanfaat bagi masyarakat umum yang ingin tahu mengenai riasan mata ala Korea Aegyo-Sal.
Pembuatan Video Tutorial Penataan Rambut Teknik Bergelombang (Hollywood Wave)
Authors: Gebie Gebie Indah Mulya , Sitti Nursetiawati
Published: January 2023

Penataan rambut mengalami perubahan tergantung pada periode, tradisi, geografis dan kondisi sosial. Berkembangnya penataan rambut klasik menjadi unsur dasar yang memberi nuansa kuat pada penataan rambut modern atau yang sifatnya komersial. Kembalinya penataan rambut klasik di era modern menjadi suatu tren baru Penataan Rambut Teknik Bergelombang (Hollywood wave). Seperti di era tahun 70-90an yang merupakan gaya rambut iconic dari seorang artis Hollywood Bernama Marilyn Monroe. Penataan rambut teknik bergelombang (Hollywood Wave) memiliki ciri khas yang berbeda dengan penataan rambut curly. Bentuk penataan rambut Hollywood wave memiliki tipe bentuk rambut gelombang seperti huruf S, sedangkan penataan rambut curly memiliki tipe bentuk rambut bergulung seperti huruf O, Pegas atau Per.

 Penelitian ini bertujuan untuk membuat sebuah produk video tutorial yang layak. Proses di dalam pembuatan video ini terdiri dari proses perencanaan pra produksi, produksi, pasca produksi, proses penelitian, proses pengolahan data dan juga hasil penelitian. Hasil pembuatan video ini divalidasi oleh dua ahli yaitu Ahli Media dan Ahli Materi. Kriteria validasi yang di dapat oleh ahli materi adalah 93,8%, dari ahli media 97%. Dapat disimpulkan bahwa video tersebut Sangat Layak untuk digunakan sebagai media alternatif serta mempermudah mahasiswa program studi tata rias dan masyarakat umum untuk mendapatkan informasi dan pengetahuan terkait video tutorial penataan rambut teknik bergelombang (Hollywood wave)
Peran self efficacy dalam memoderasi pengaruh digital literacy terhadap entrepreneurial intention
Authors: Rojoki Manullang Dominikus , Waspada Ikaputera
Published: January 2023

This research is motivated by the low entrepreneurial intention of Vocational High School (VHG) students in East Jakarta. This study aims to determine and analyze the mediating effects of self-efficacy on the effect of digital literacy on students' entrepreneurial intention. The method used in this study is an explanatory survey research with data collection techniques through questionnaires and observations. The population of this study were all students SMK 22 dan 67 in Jakarta Timur of class XI class 2021/2022 as many as 316 students, while based on Slovin calculations the sample of this study was 70 students. The collected data were then analyzed using descriptive analysis techniques and multiple linear regression with Moderate Regression Analysis (MRA). The results showed that: 1) the level of digital literacy, self-efficacy, and entrepreneurial of students were in the very high category. 2) Digital literacy affects the entrepreneurial intention of students. 3) self-efficacy mediate the effect of digital literacy on students' entrepreneurial intention. These findings indicate that to increase intention in entrepreneurship, the learning process in SMK needs to be emphasized on efforts to increase digital literacy and self-efficacy
Peran servicescape terhadap trust dan dampaknya pada minat beli yang dimoderasi oleh personal selling pada live streaming produk tas di facebook
Authors: Daud Qiven , Simamora Virgo
Published: January 2023

This study aims to examine the effect of servicescape and trust on interest in buying bags moderated by personal selling. This research was conducted in the Greater Jakarta area. The sampling technique used purposive sampling method. This research data is primary data collected by distributing questionnaires to consumers using live streaming on Facebook. Hypothesis testing was carried out using the PLS data analysis method. based on statistical tests, the results of the study show that servicescape has a positive and significant effect on trust and significantly on buying interest. While personal selling moderation has no significant effect on buying interest
VOLATILITY SPILLOVER, HEDGING AND PORTFOLIO DIVERSIFICATION BETWEEN OIL MARKET AND S&P SECTORAL INDICES
Authors: GENÇYÜREK Ahmet Galip , EKİNCİ Ramazan , AĞAN Büşra
Published: January 2023

The study aims to analyze volatility spillover between the oil market (WTI) and S&P Energy, Financial, and Industry sector indices in terms of conditional correlation and variance causality. DCC-GARCH and Hafner-Herwartz (2006) Variance Causality Analysis were used to analyze the daily data span from January 2012 to December 2019. As a conclusion, in this study has been revealed that there is a positive time-varying conditional correlation between the oil market and sector indices. Besides, hedge ratio and risk minimizing portfolio weights, which are vital for investors, have been calculated based on these data. The cheapest hedging transaction with the oil market occurs with the financial sector, the most expensive one takes place with the energy sector. Also, it has been determined that volatility transmission is from sector indices to the oil market. This situation means that, S&P sector indices play a key role (resource of information- emit information) in volatility spillover. The results provide important information to researches, investors and policy-makers.

Çalışmanın amacı, petrol piyasası (WTI) ile S&P Enerji, Finansal ve Sanayi sektör endeksleri arasındaki ilişkiyi koşullu korelasyon ve varyans nedenselliği bakımından incelemektir. DCC-GARCH ve and Hafner-Herwartz (2006) Varyans Nedensellik modelleri Ocak 2012-Aralık 2019 dönemi günlük verilerini analiz etmek için kullanılmıştır. Çalışma sonucunda petrol piyasası ile sektör endeksleri arasında zamana bağlı değişim gösteren pozitif koşullu korelasyon ilişkisi olduğu belirlenmiştir. İlaveten, elde edilen sonuçlardan yararlanarak yatırımcılar açısından oldukça önemli olan korunma rasyosu ve riski minimize eden portföy ağırlıkları hesaplanmıştır. Petrol piyasası ile en ucuz korunma işlemi finans sektörüyle, en pahalı korunma işlemi ise; enerji sektörüyle olmuştur. Bunun yanında, volatilite iletiminin sektör endekslerinden petrol piyasasına doğru olduğu belirlenmiştir. Bu durum S&P sektör endekslerinin volatilite yayılımında önemli bir role sahip (bilginin kaynağı, bilgi yayan) olduğunu göstermektedir. Elde edilen sonuçlar araştırmacılar, yatırımcılar ve politika yapıcılar açısından önemli bilgiler sunmaktadır.
The Kataevo Island Arc System of the Paleoasian Ocean (Transbaikalia): Composition, Age, Paleomagnetism, and Formation Geodynamic Settings
Authors: Gordienko I.V. , Metelkin D.V. , Lantseva V.S. , Elbaev A.L.
Published: January 2023

—Based on new data on the geology, composition, U–Pb isotopic age, and paleomagnetism of the metavolcanic rocks of the Kataevo Formation, we consider the geodynamic conditions of their formation and alteration. The Kataevo Formation metavolcanic rocks belong to the K–Na-high-alumina andesite–andesibasalt–basalt volcanic series. Results for U–Pb analysis of magmatic zircon (SHRIMP II, 8 spots) from a metaandesibasalt sample of the stratotype section on Ungo River yielded and age of 852 ± 9 Ma. Isotope systems for Sm–Nd yield a positive εNd(852) = +9.29, which indicates a juvenile magmatic source, close to depleted mantle (DM), with a Neoproterozoic protolith TNd(DM) model age. The content of the less mobile HFSE and REE (ppm) is consistently low for Nb (8–15), Ti (7074–12,410), Ta (0.32–0.93), Eu (1.80–2.29), Се (50–79), Y (21–25), Yb (2.1–2.8), Rb (10–24) and elevated for Sr (1000–1500), Zr (170–270), La (25–41), and Ba (600–800). All studied parameters place the metavolcanic rocks close to the contemporary Kurile–Kamchatka type of developed island arcs. Paleomagnetic analysis of the section of metavolcanic rocks shows a complete remagnetization ca. 120 Ma. This is synchronous with manifestations of intraplate basaltoid magmatism in the studied region, the most typical example of which is the Lower Cretaceous Khilok Formation.
El sistema educativo Alexia y su influencia en la gestión educativa en la ONG Coprodeli, 2021
Authors:   , Yovera Osorio Juan Manuel Junior , Quispe Tantas Marco Antonio
Published: January 2023

La presente investigación analiza la influencia y desempeño del sistema educativo Alexia en un grupo de instituciones que pertenecen a la ONG Coprodeli mediante la aplicación de encuestas respecto a su nivel de interacción, facilidad de uso en el ámbito educativo haciendo énfasis en la necesidad de la implementación de este sistema en todas las escuelas pertenecientes a la ONG como un añadido a su excelencia educativa. El primer capítulo describe el estado actual de la ONG a nivel educativo y tecnológico, resaltando las ventajas del uso de un sistema basado en la nube para mantener la comunicación e interacción constante entre los distintos elementos que conforman el entorno educativo y mencionando también, la coyuntura sanitaria que las escuelas afrontan actualmente debido a la pandemia Covid-19. El segundo capítulo se aborda el marco teórico y se resalta la importancia de este estudio y el posible impacto a la excelencia educativa en base al antecedente, con lo cual se determinan los objetivos a alcanzar. El tercer capítulo se encarga de detallar el diseño, enfoque y las muestras sobre las que se realizaran la recolección de datos basadas en las encuestas dirigidas a las instituciones de muestra. En el cuarto capítulo observamos los resultados obtenidos después de la aplicación de la encuesta a través de los diferentes grafico estadísticos, en el último capítulo, informamos los resultados en la investigación determinando si el uso de Alexia es beneficioso para la comunidad educativa.
Efecto del tiempo de conservación de ovarios a 5 °C sobre la calidad de los complejos ovocitos-cúmulos (COC´s) en alpacas (Vicugna pacos)
Authors:   , Lizana Zapata Paola Angeolina
Published: January 2023

En alpacas, uno de los mayores obstáculos en la investigación en gametos femeninos es la dificultad de obtener muestras de animales en pie, por ello se recure al empleo de ovarios procedentes de camal; sin embargo, el tiempo que transcurre entre la colección y transporte de ovarios y la posterior obtención de los complejos ovocitos-cúmulos (COC’s, por sus siglas en inglés) puede ser muy prolongado, lo cual podría afectar la calidad de estos últimos. El objetivo del presente trabajo fue evaluar el efecto del tiempo de conservación de ovarios de alpaca sobre la calidad de los COC’s en alpacas. Para ello se emplearon 48 ovarios de alpacas sanas de entre 3 a 4 años obtenidos del camal, los cuales fueron mantenidos a 5 °C y distribuidos equitativamente en dos tiempos de almacenamiento (24 y 48 horas respectivamente). Posteriormente mediante aspiración folicular se colectaron los COC’s, Se determinó la calidad de estos como excelente (1), buena (2), regular (3) y mala (4) en base a la caracterización morfológica. Lográndose obtener un total de 301 ovocitos (n=125 en 24 horas, n=176 en 48 horas). Los porcentajes de COC’s de mejor calidad (excelente y buena) fueron estadísticamente mayores (p<0.05) en los ovarios conservados a 24 horas (4% y 10.4%) en comparación a los obtenidos de ovarios conservados por 48 horas (0% y 2.8%). Nuestros resultados sugieren que la calidad de los COC’s se ve afectada por el tiempo de conservación y que un tiempo de almacenamiento de 24 horas en comparación a 48 horas permite obtener mayor número de ovocitos de excelente y buena calidad; es decir, aptos para biotecnologías reproductivas en alpacas.