bluuebunny/crossref_metadata_2025 huggingface dataset:
Acceptance and Commitment Therapy (ACT) Enriched with Compassion Focused Therapy (CFT) on Psychological Distress in Patients under Methadone Maintenance Treatment (MMT)
Authors: Ahmadabadi Mahdi Shomali , Zabihi Mohsen , Barkhordari Atefeh , Dastjerdi Qasem , Movahedian Zahra , Heydari Khormizi Seyed Moezoddin , Ahmadi Mehrabadi Seyed Reza , Aref Zahra
Published: April 2023

Introduction: Mental problems caused by opioid addiction or drug withdrawal can increase the risk of relapse in methadone maintenance treatment. The present study was conducted to compare the efficacy of acceptance and commitment therapy enriched with compassion-focused therapy on the effect of sertraline and venlafaxine on patients' psychological distress under methadone maintenance treatment.
Method: This study was a clinical trial with a pre-test and post-test design. Forty patients under methadone maintenance treatment were selected by voluntary sampling and randomly divided into two groups. The first group received acceptance and commitment therapy enriched with compassion-focused therapy and venlafaxine, and the second group received acceptance and commitment therapy enriched with compassion-focused therapy and sertraline for intervention days. The patients were evaluated based on the anxiety, stress, and depression questionnaire. The data were analyzed using the paired t-test and analysis of covariance at a significance level of 0.01.
Results: Both venlafaxine, and sertraline plus acceptance and commitment therapy enriched with compassion-focused therapy, were influential on psychological distress and its dimensions (depression, anxiety, and stress) (P<0.001). Sertraline had a more significant effect on psychological distress, and anxiety than venlafaxine (P<0.01). No significant difference was observed between them on depression and stress (p>0.05).
Conclusion: Sertraline is more effective than Venlafaxine in controlling psychological symptoms in methadone maintenance treatment.
The Culprit of Increased Complaints in IVF Clinics: New Technologies or the Growing IVF Popularity?
Authors: Reza Sadeghi Mohammad
Published: April 2023

The Article Abstract is not Available.
Comparison of In-House Microfluidic Device and Centrifuge-Based Method Efficacy in Sperm Preparation for Assisted Reproductive Technology
Authors: Phairatana Tonghathai , Prateepchaikul Thanaporn , Navakanittworakul Raphatphorn , Choksuchat Chainarong
Published: April 2023

Background: Sperm DNA fragmentation can affect reproductive outcomes in assisted reproductive techniques (ART), and it is a concern in density gradient centrifugation (DGC). By contrast, microfluidic approaches allow the selection of highly motile sperm with low DNA fragmentation index (DFI). The purpose of current study, was to compare the efficacy of a microfluidic device designed in-house in comparison with DGC.
Methods: Nineteen healthy men with normal semen profiles were included in the study. Semen samples were individually aliquoted for three sperm preparation analyses (crude and processed with to either DGC or the microfluidic method). Sperm parameters of the samples were evaluated along with DNA fragmentation using the terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) method.
Results: Sperm processed using the microfluidic method showed a significantly lower DFI than those obtained using DGC and in crude semen, with DFI of 1.1%, 3.5%, and 4.9%, respectively. Although the microfluidic method yielded significantly lower sperm concentrations than DGC, no significant differences were observed in total motility, progressive motility, curvilinear velocity, straight-line velocity, or normal morphology.
Conclusion: Using the in-house microfluidic device, sperm with lower DFI was effectively isolated when compared with DGC. The motility and normal morphology rates were comparable among the samples.
Evaluation of the Utility of Seminal Plasma Resistin and Leptin in Predicting Successful Surgical Sperm Retrieval in Men with Non-Obstructive Azoospermia
Authors: Kamel Amer Medhat , Zohdy Wael , GamalEl Din Sameh Fayek , Hosni Moawad Hanan , Hasan El Saedy Dina Atef , Zaki Gamal Eman Ahmed , Ragab Ahmed
Published: April 2023

Background: The purpose of the current study was evaluation of the utility of seminal plasma (SP) resistin and leptin in predicting successful surgical sperm retrieval (SSR) in men with non-obstructive azoospermia (NOA).
Methods: This prospective comparative study was conducted in the andrology clinic of a specialized fertility center. In total, 53 NOA men as candidates for either first time micro‐testicular sperm extraction (micro-TESE) or repeat micro-TESE and 28 normozoospermic controls were included. ELISA was used for measurement of SP resistin and leptin levels in all participants. Significance level was defined as p< 0.05. 
Results: The current study demonstrated a significant positive correlation between estradiol (E2) level in serum and SP resistin (r=0.342, p=0.025). Also, there was a highly significant positive correlation between SP leptin and SP resistin (r=0.568, p= 0.001). Interestingly, SP leptin was the only variable that demonstrated a significant correlation with eventful micro-TESE outcome in men who underwent micro-TESE for the first time. Finally, ROC curve showed that SP leptin level of 4.05 ng/ml predicted successful SSR in men who underwent micro-TESE for the first time with a sensitivity of 73.3% and a specificity of 75% as 11 out of 27 (41%) cases showed eventful micro-TESE at or above this cut-off level [AUC of 0.747, 95% CI, lower bound of 0.555, and upper bound of 0.939, p=0.030].
Conclusion: SP leptin can be used as a non-invasive biomarker to predict successful SSR in NOA cases undergoing first time micro-TESE, while SP resistin failed to play the same role.
The Effect of Follitropin Alfa in Controlled Ovarian Stimulation Protocol for In Vitro Fertilization Cycles
Authors: Prasetiawati Novita , Mulia Sundari Ayu , Supriyadi Agus , Sjarbaini Hadi , Tarigan Sudirmanto , Suardana Gde , Pariyanti Gangsar , Rosaria Indah Deana , Purwatyningsih Euis , Bowolaksono Anom
Published: April 2023

Background: Follitropin alfa (FA) is one of the most widely used exogenous gona-dotropins in both agonist and antagonist protocols for controlled ovarian stimulation (COS) and in vitro fertilization (IVF). However, reports of its effectiveness are limited, particularly in terms of its impact on overall IVF outcomes and ovarian hyperstimulation syndrome (OHSS). Therefore, in this study, FA competency was investigated by evaluating its effect on IVF outcomes and OHSS, administering agonist and antagonist COS protocols.
Methods: A retrospective study with 120 subjects was conducted. Outcomes com-prising the number of retrieved and fertilized oocytes, quality of embryos, and clinical pregnancies were assessed. Statistical correlation between FA dose, IVF outcomes, and the incidence of OHSS was also analyzed. All statistical analyses were performed at 95% confidence level.
Results: There was no significant difference in both protocols regarding retrieved oocytes (p=0.604), fertilized oocytes (p=0.761), embryo quality including good, average, poor embryo (p=0.875, p=0.565, p=0.785), and clinical pregnancy (p= 0.844). However, FA doses in the agonist protocol were shown notably higher (p= 0.001). Negative correlations were also observed between FA dose and the number of retrieved oocytes (r=-0.255, p<0.01), fertilized oocytes (r=-0.296, p<0.01), and good quality embryos (r=-0.231, p<0.05).
Conclusion: Our study suggested that FA yields similar outcomes in both COS pro-tocols, but agonist protocols require higher doses of FA and evaluation of its effect on OHSS is an important area of research for further investigation.
Total and Intratumoral CD8+ T Cell Expressions are Correlated with Miller Payne Grading and WHO Clinical Response of Neoadjuvant Chemotherapy
Authors: Panigoro Sonar Soni , Maulanisa Sinta Chaira , Kurnia Ahmad , Purwanto Denni Joko , Rustamadji Primariadewi , Herqutanto Herqutanto , Sandra Ferry
Published: April 2023

BACKGROUND: Chemotherapy has reported to stimulate immune system through direct activation of cluster of differentiation (CD)8+ T cells. Neoadjuvant chemotherapy (NAC) is known to improve the clinical response of locally advanced breast cancer (LABC) patients. However, the immune response-related factor evaluation of NAC in LABC patients has not been routinely performed. Therefore, current study was conducted to evaluate the correlation of NAC-induced CD8+ T cell with chemotherapy response based on Miller Payne grading and World Health Organization (WHO) criteria.METHODS: LABC patients were recruited and data regarding age, gender, tumor, nodal stages, histopathological grade, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and Ki67 were obtained. Biopsy and mastectomy tissues were collected and processed for hematoxylin-eosin and CD8 immunohistochemical staining. CD8+ T cell expression in peritumoral and intratumoral areas were documented and measured. Clinical responses based on Miller Payne grading and WHO were analyzed and correlated with CD8+ T cell expression.RESULTS: There were more subjects with high expression of total (80%), intratumoral (82.5%) and peritumoral (65%) CD8+ T cell expressions. The total (p=0.013) and intratumoral (p=0.015) CD8+ T cell expression, but not peritumoral CD8+ T cell expression, were significantly correlated with Miller Payne Grading. The total (p=0.009) and intratumoral (p=0.001) CD8+ T cell expressions were also significantly correlated with WHO clinical response.CONCLUSION: Total and intratumoral CD8+ T cell expressions are correlated with Miller Payne grading and WHO clinical response of NAC. Therefore, total and intratumoral CD8+ T cell expressions could be suggested as a predictive marker for clinical response of NAC.KEYWORDS: breast cancer, neoadjuvant chemotherapy, CD8, clinical response, Miller Payne, intratumoral, peritumoral
ESAT-6-Ag85C-polyHistag Antigen Fusion is Potential as Vaccine Candidate for Tuberculosis
Authors: Purwanti Ratu , Indrati Agnes Rengga , Suraya Nida , Montain Maya Marinda , Atmosukarto Ines , Nurainy Neni , Parwati Ida
Published: April 2023

BACKGROUND: BCG vaccine has been proven to be effective protection against tuberculosis (TB) meningitis and miliary TB. However, for protection against pulmonary TB, the results remains vary widely. Recombinant vaccine consisting of two immunodominant Mtb antigens ESAT-6-Ag85C-polyHistag (EAH) is currently being developed as a new TB vaccine candidate for booster. An immugonecity test for vaccine candidates is required in the initial phase to evaluate cellular immune response. This study was conducted to evaluate the cellular immune response by measuring interferon-gamma (IFN-γ) cytokines produced by T cells after ex vivo stimulation by TB EAH antigen fusion.METHODS: Peripheral blood mononuclear cells supernatant samples were collected from 16 new pulmonary TB subjects, 17 pulmonary TB in treatment subjects, and 10 healthy subjects. Samples were tested for IFN-γ level with enzyme-linked immunosorbent assay (ELISA). Kruskal-Wallis test was used to test the differences between IFN-γ levels among three groups, and followed by post-hoc analysis using Mann Whitney.RESULTS: The median of IFN-γ levels for new pulmonary TB, pulmonary TB in treatment, and healthy subjects were 17.09 (2.65-140.14) pg/mL, 4.36 (2.43-21.41) pg/mL, and 2.91 (2.39-3.85) pg/mL, respectively. There were significant differences of IFN-γ levels between new pulmonary TB group and pulmonary TB in treatment group (p=0.012), between new pulmonary TB group and healthy group (p=0.001), and also between pulmonary TB in treatment group and healthy group (p=0.035).CONCLUSION: Results show that TB EAH could stimulate cell-mediated immune responses in the three groups, with the highest IFN-γ levels are found in new pulmonary TB group, suggesting a potential immunodominant antigen fusion for vaccine candidate development.KEYWORDS: Ag85C, ESAT-6, immunogenicity test, IFN-γ, TB vaccine candidate, tuberculosis
Resolution to Inflammation: Its Role in Reducing Fibrosis and Tissue Repair
Authors: Meiliana Anna , Wijaya Andi
Published: April 2023

BACKGROUND: Many chronic disorders, including vascular diseases, metabolic syndrome, and neurological diseases, are known to share a common factor of excessive inflammation. It takes a lot of energy to heal damaged tissue, which is a complicated process. The outcome is often suboptimal, with some degree of fibrosis, depending on the tissue's ability to regenerate and the strength of the inflammatory response. We may get new insights into disease causation and therapeutic strategies by better understanding endogenous regulatory points within the inflammatory response.CONTENT: Despite of the benefit in raising an inflammatory response, it also have unfavourable effects. Unresolved inflammation can over accumulate collagenous connective tissue and induce fibrosis, promote tissue dysfunction, and finally organ failure. Currently, the resolution of inflammation was described in terms of contemporary molecules as a different mechanisms from anti-inflammatory, since in resolution, the pathogen and apoptotic cells crumbs will be cleared and the macrophages will set back the tissue homeostasis. An active transition in the mediators that predominate in exudates occurs in conjunction with the remission of inflammation. These groups of inborn pro-resolution named resolvins, maresins, and protectins work to reduce inflammation by triggering certain pathways that support homeostasis rather than by suppressing the immune system.SUMMARY: The resolution of inflammation, once believed to be a passive process, is now understood to entail active biochemical programs that allow inflamed tissues to regain equilibrium. In this review, we spotlight the resolution to inflammation as a strategy to prevent tissue fibrosis and hinder the organ damage.KEYWORDS: inflammation; resolution; fibrosis; wound healing; specialized pro-resolving mediators.
Las funciones constitucionales del Gobierno en España
Authors: Álvarez Rodríguez Ignacio
Published: April 2023

El presente texto es una puesta al día de las funciones que la Constitución española de 1978 atribuye al Poder Ejecutivo, uno de los tres poderes clásicos y quizá el que mayor importancia tiene en el devenir cotidiano de los asuntos nacionales. A tal fin se hace un breve repaso a la cuestión desde la óptica comparada y desde la historia constitucional patria, para pasar después a analizar cada una de las funciones constitucionales que el Gobierno tiene conferidas, en base a la clásica divisoria entre la función de dirección política, la función de dirigir la Administración civil y militar y el ejercicio de la potestad reglamentaria. Posteriormente se hace una referencia al control de los actos del Gobierno, tanto político como jurídico, así como a la labor de ayuda que le prestan ciertos órganos institucionales, tales como el Consejo de Estado y el Tribunal de Cuentas, para finalizar con una reflexión que sintetiza los hallazgos resultantes.
La batalla de los apellidos: un análisis bajo teoría de juegos de las normas colombianas que permiten a los padres elegir el orden de los apellidos de sus hijos
Authors: Gaviria Juan Antonio
Published: April 2023

La ley colombiana determinaba que los padres debían registrar a sus hijos asignándoles como primer apellido el de su padre. En noviembre de 2019, la Corte Constitucional precisó que tal regla viola la igualdad de géneros y permitió a los padres asignar a sus hijos como primer apellido bien sea el paterno o el materno. Este texto investigativo, con metodología basada en teoría de juegos y en modelos del análisis económico de derecho de familia para aplicarlos, lege lata, a las nuevas normas que permiten a los padres negociar entre sí sus derechos de propiedad sobre los apellidos de sus hijos, haciendo énfasis en padres casados o en unión libre. El texto también estudia dicha negociación bajo los modelos de batalla de los sexos y del juego de la gallina. Tal enfoque ofrece nuevas perspectivas no solo sobre los efectos de la reciente jurisprudencia sino también sobre el análisis económico del matrimonio y del derecho de familia. El texto concluye que: la negociación de los apellidos será compleja no por razones legales sino económicas, como el monopolio bilateral existente entre los padres y el ser un apellido un objeto indivisible que no se comercia en un mercado tradicional.
Economía política del suelo y vivienda en Colombia: una perspectiva libertaria
Authors: Ramírez Ríos John Fredy
Published: April 2023

Este artículo controvierte la tesis de que la informalidad y segregación en los mercados de suelo y vivienda en Colombia, tienen su causa determinante en la prevalencia de prácticas económicas de naturaleza “neoliberal”, es decir, que están al margen de todo control público efectivo o de salvaguarda del bien común. Tesis defendida por reconocidos académicos locales del urbanismo de clara orientación neomarxista o cepalina como Emilio Pradilla, Samuel Jaramillo o María M. Maldonado, entre otros. A partir de postulados libertarios, de raíz austriaca y anarcocapitalista, se plantea que ha sido más bien el intervencionismo estatal redistributivo –muy defendido por esos académicos–; lo que precisamente da lugar a tales prácticas que poco o nada tienen de “liberales”. Se comienza explicando cómo desde 1950, con la llegada a Colombia del desarrollismo neokeynesiano liderado por Lauchlin Currie; se mantuvo un orden social mercantilista parecido al de la época de la colonia. Así el “neoextractivismo” se terminó de reposicionar con la Constitución Política de 1991, al declararse Colombia un Estado Social de Derecho; y la posterior promulgación de la Ley 388 de 1997 de Desarrollo Territorial. Desde ese entonces, clientelismo y corporativismo se han exacerbado en los ámbitos propios de la administración pública territorial; y las ciudades siguen siendo precarias, pobres y desiguales. Se concluye diciendo que la única forma de superar esas realidades es liberalizando verdaderamente el suelo y la vivienda; y reforzando, al tiempo, el debilitado sistema judicial retributivo, de garantía a los derechos fundamentales y concomitantes de libertad, vida y propiedad.
Justicia como equidad : entre distribución y reconocimiento
Authors: Aguayo Pablo
Published: April 2023

En este artículo muestro que los críticos del paradigma liberal distributivo confrontan forzadamente una concepción de la justicia centrada en la distribución con otra centrada en el reconocimiento. Si bien autores como Iris Marion Young, Axel Honneth y Nancy Fraser defienden paradigmas diferentes, todos ellos comparten la idea según la cual las concepciones liberales centradas en la justicia distributiva son insuficientes para dar cuenta de los problemas de la justicia social. En el transcurso de este artículo discuto que en dichas propuestas existe una comprensión estrecha de la justicia distributiva, especialmente de la concepción que John Rawls elaboró en ATheory ofJustice (1971). Expongo que el núcleo de dicha falta de comprensión reside en la no distinción entre la justicia asignativa (allocativejusticie) y la justicia distributiva (distributive justice). Una vez aclarada la distinción anterior, defiendo la tesis de que la concepción de la justicia distributiva propuesta por Rawls no solo va más allá de los márgenes de la justicia asignativa, sino que ofrece suficientes argumentos para enfrentar las demandas de reconocimiento dentro de un marco liberal igualitarista. De esta forma, mi ejercicio filosófico va justo en la dirección opuesta a las recomendaciones que Young propuso en Justice and Politics of Difference cuando afirma que «el concepto de distribución debe limitarse a los bienes materiales» (1990, p. 8)3 .
Reconocimiento : ¿más acá o más allá de la justicia?
Authors: Calvo Ángela
Published: April 2023

A partir de la publicación de Teoría dela justicia, de John Rawls, la filosofía política se ha concentrado en definir principios de justicia, considerados garantes suficientes de la estabilidad social, a partir de la idea de que «la justicia es la primera virtud de las instituciones sociales, como la verdad lo es de los sistemas de pensamiento» (Rawls, 1999, p. 3)1 . Parece existir un consenso generalizado acerca del hecho de que las sociedades democráticoliberales tienen fundamentos normativos que exigen el respeto a la igual dignidad de todos los seres humanos —con independencia de su etnia, religión, opción de género o clase social— en virtud de su poder moral de elegir un plan de vida acorde con los propios valores y fines, el cual debe ser protegido legalmente. En el marco de este consenso, buena parte de las teorías de la justicia se inscriben en el paradigma de la distribución de bienes (recursos, libertades y derechos), al concordar en que el objetivo normativo de la justicia es la superación de los diversos tipos de desigualdad social.
El reconocimiento como presupuesto del lenguaje, de la intersubjetividad y del sujeto moral
Authors: Zan Julio de
Published: April 2023

El término «reconocimiento» adquirió rango filosófico a fines del siglo XVIII y comienzos del XIX, a partir de Fichte y, especialmente, con Hegel. Estos antecedentes son bien conocidos, pero el significado del término en aquellos filósofos del idealismo alemán se ha oscurecido o ha sido dejado de lado. Me parece que puede resultar interesante volver a las fuentes para confrontar con ellas las actuales teorías del reconocimiento. Este artículo se ocupa, en primer término, de recuperar el significado histórico-filosófico de la figura fenomenológica de la lucha por el reconocimiento en el pensamiento de Hegel. Esta interpretación se realiza desde un punto de vista ligado al giro lingüístico de la filosofía del siglo XX, el cual permite explicitar de otra manera los resultados de la reconstrucción de Hegel para la explicación de los presupuestos de la filosofía teórica. Se examina la comprensión del reconocimiento como una condición necesaria de la posibilidad del significado y de la validez intersubjetiva del saber en general. Se revisa, finalmente, la relación y la diferencia entre el paradigma moral del reconocimiento y la filosofía política, y se confrontan las propuestas de actualización del modelo de la lucha por el reconocimiento como principio ético en los planteamientos de Axel Honneth y Paul Ricœur.
Autonomía y reconocimiento
Authors: Giusti Miguel
Published: April 2023

Uno de los ejes principales en torno a los cuales gira el debate sobre el paradigma del reconocimiento en la actualidad es el de la interpretación adecuada de la relación entre los conceptos de autonomía y reconocimiento. El telón de fondo es, naturalmente, la controversia que involucra a Kant y Hegel en su interpretación de la libertad, pero esa controversia parece prolongarse o hallar un eco en muchas de las discusiones actuales. Aunque se ha escrito ya mucho sobre el tema, lo que propongo aquí es una exposición sintética de las notorias discrepancias y de las sutiles similitudes que pueden detectarse en la confrontación inicial de las posiciones de Kant y Hegel, con el ánimo de mostrar también indirectamente con qué facilidad pueden ofrecerse interpretaciones que pierden de vista el fructífero parentesco entre ambas.
Reconocimiento y crítica : apuntes sobre la obra reciente de Axel Honneth
Authors: Madureira Miriam Mesquita Sampaio de
Published: April 2023

Reconocimiento y crítica podrían parecer expresiones opuestas. Reconocer significa, de alguna forma, aceptar y el término reconocimiento parece asociarse a la afirmación y no a la crítica de algo. Sin embargo, la última versión relevante de la teoría crítica de la Escuela de Frankfurt —la desarrollada por Axel Honneth— consiste precisamente en una teoría del reconocimiento y la intención de dar continuidad a la crítica inmanente de la sociedad moderna capitalista, objeto de toda aquella teoría, es evidente en ella desde su surgimiento en La lucha por el reconocimiento (1992).
Educación, derechos y reconocimiento
Authors: Ruiz Carlos
Published: April 2023

En este artículo intentaré destacar, en primer lugar, las relaciones entre educación, derechos y reconocimiento en el pensamiento de Hegel. A mi juicio, esto permite referirse a temáticas de gran importancia para la reflexión sobre la educación y sus relaciones con la política y la ciudadanía hoy. En segundo lugar, consideraré brevemente cómo son analizadas estas relaciones, especialmente las vinculadas a la educación y el reconocimiento, en dos filósofos contemporáneos que han revitalizado al concepto de reconocimiento en trabajos muy importantes e influyentes: me refiero a Taylor y Honneth. Finalmente, haré una breve indagación sobre los aportes que puede hacerse a los estudios sociales sobre educación a partir de estas perspectivas.
Procesos constitucionales en América Latina
Authors: García Belaúnde Domingo
Published: April 2023

Antes de empezar mi exposición, quisiera hacer una brevísima referencia a lo que significa esta actuación y las que se llevan, a cabo estos días con la presencia de los profesores Pogany, a quien acabamos de escuchar, y Adelman, ambos de la Universidad de Warwick. Uno de los aciertos de la actual administración de nuestra Facultad, cuyo Decano preside en estos momentos nuestras deliberaciones, es haber buscado un intercambio con universidades del exterior.
Principios constitucionales de la administración de justicia
Authors: Zolezzi Ibárcena Lorenzo
Published: April 2023

De modo muy general podría decirse que a lo largo de estos sesenta años que van de 1933 a 1993, en materia judicial han habido tres grandes tendencias en su plasmación constitucional. Una primera tendencia ha sido la búsqueda de un método para la selección de magistrados, en algunos casos este método ha sido expresamente diseñado para aliviar al Poder Judicial de la presión del poder político, especialmente en los nombramientos, que podría forzar a los magistrados a un pago de favores en un momento dado; en consecuencia, una de las líneas de desarrollo constitucional ha sido la búsqueda de un sistema para la designación de magistrados.
Presidencialismo y la Constitución de 1925 en Chile
Authors: Landa Arroyo César
Published: April 2023

La reciente transición a la democracia en América Latina y en otros países del mundo ha revivido el interés por el estudio de las instituciones y procedimientos políticos. Esto es un hecho positivo ya que hasta hace poco los dentistas políticos no consideraban este aspecto importante de los estudios políticos y por lo tanto lo dejaban en manos de sus colegas menos académicos: principalmente los abogados. A medida que varios países comenzaron a establecer gobiernos democráticos, académicos de diversas disciplinas comenzaron a darse cuenta que las formas institucionales no son merOs instrumentos supra estructurales cuyo diseño puede dejarse en manos de los abogados o sujetos a la imaginación de los políticos. Hoy en día, existe consenso generalizado que las instituciones y procedimientos pueden tener, y de hecho tienen, un impacto importante en la estabilidad, durabilidad y eficacia del sistema político.
Antifungal Activity of Botanicals and Biological agents against Sclerotium rolfsii Causing Foot and Root Rot Disease of Lentil
Authors: Hossain Md. Mokarrom , Azad Md. Abul Kalam , Khalequzzaman K.M.
Published: April 2023

Background: Foot and root rot disease caused by Sclerotium rolfsii is a destructive soil borne disease of lentil (Lens culinaris). The present experiment was conducted to determine the inhibitory effect of thirteen plant extracts and two bio-control agents on in vitro mycelium growth of S. rolfsii. Methods: The experiment was conducted in the Laboratory of Pulse Research Center, RARS, BARI, Ishurdi, Pabna, Bangladesh during rabi season in 2015. Seven isolates of S. rolfsii were collected from foot and root rot affected lentil plant. Antifungal activity of thirteen botanicals and two biocontrol agents (T. harziznum and T. viride) was tested against a fast growing isolate (Sc-38) of the pathogen following poisoned food technique. Result: Out of thirteen botanicals, only Black cumin inhibited colony growth of S. rolfsii, where the colony diameter ranged 0.00-6.00 cm at different days after incubation. A moderate inhibition was achieved with Tulsi at 3, 6 and 9 DAI compared to control. Amendment of PDA with compost and liquid T. harziznum and T. viride remarkably inhibited the colony growth of S. rolfsii compared to control. Efficacy of four treatments of biocontrol agents was much better than botanical treatments. Two botanical extracts (Black cumin and Tulsi) and biocontrol agents (T. harzianum and T. viride) were found effective against S. rolfsii.
Exploring Gender- and Race-Based Financial Stereotypes in Black and White College Students
Authors: Dzokoto Vivian , Hagiwara Nao , Belgrave Faye
Published: April 2023

Financial behavior disparities across race and gender persist in the United States. Historical and structural factors contribute to such disparities. It is important to understand the psychological mechanisms underlying these disparities to begin to achieve wealth equity. This study addressed one potentially relevant psychological construct: stereotypes about financial behaviors. Using a sample of 114 college students from a large public university, the study explored societally held beliefs about financial behaviors. The results showed that White men were generally viewed as more financially competent than White women, who were viewed as more financially competent than Black men and Black women. Implications for financial education and financial behaviors are discussed.
Financial Literacy Content Areas for Professional Athletes: Evidence From a Qualitative Study
Authors: Moolman Jaco
Published: April 2023

Many people spend their working lives accumulating financial resources to sustain them once they retire, which is usually in their early to mid-60s. However, the working lives of professional athletes are unique, with finite sports careers and a range of possible challenges during the transitional phase after their sports careers have ended. This study shows an illustrative framework for financial literacy content areas required by professional athletes to achieve long-term financial well-being. Actor–network theory guided the completion of 27 semistructured face-to-face interviews as well as 10 structured follow-up interviews conducted in South Africa among networks of rugby and cricket players to develop and validate the framework. The research findings suggest professional athletes should take responsibility for their financial planning and have the financial literacy skills to seek, interpret, and apply financial advice. The findings also provide some considerations for education initiatives to improve the financial literacy of professional athletes. The results of this study have implications for professional athletes as well as financial planners, educators, and others positioned to potentially influence the professional athletes’ financial decisions.
More Than a Score? Indirect Associations Between Credit Score and Romantic Relationship Quality in Emerging Adulthood
Authors: Saxey Matthew T. , LeBaron-Black Ashley B. , Totenhagen Casey J. , Curran Melissa A.
Published: April 2023

Higher credit scores have unique financial benefits that may aid in emerging adults’ efforts toward financial independence. Yet, it is unknown if higher credit scores may also yield romantic relationship benefits. In a sample of 916 U.S. emerging adults, we used structural equation modeling to test the indirect associations between credit score and romantic relationship quality. Credit score was positively associated with financial self-efficacy and negatively associated with financial deception. Additionally, credit score was indirectly associated with romantic relationship quality through financial self-efficacy and financial deception. We encourage educators and clinicians working with emerging adults in romantic relationships to help these emerging adults learn how to establish credit and raise their credit scores, which might improve financial and relational outcomes.
Autentikasi Cepat Kopi Spesialti Arabika Java Preanger Kultivar Typica, Sigarar Utang dan Yellow Bourbon Menggunakan Spektroskopi UV dan Metode PLS-DA
Authors: Yulia Meinilwita , Ningtyas Kurnia Rimadhanti , Widodo Slamet , Suhandy Diding
Published: April 2023

Kopi spesialti arabika dijual dengan harga lebih mahal dibandingkan dengan kopi robusta. Kopi spesialti arabika Java Preanger kultivar Typica, Sigarar Utang, dan Yellow Bourbon saat ini tersedia di pasar kopi premium dengan harga mahal dan saat ini menjadi salah satu target pemalsuan kopi. Penelitian ini bertujuan untuk mengevaluasi aplikasi metode spektroskopi UV dan metode PLS-DA (partial least squares-discriminant analysis) untuk autentikasi cepat kopi spesialti arabika Java Preanger dengan tiga kultivar berbeda. Sampel kopi bubuk spesialti arabika (Typica, Sigarar Utang, dan Yellow Bourbon) dan robusta disiapkan sebanyak total 550 sampel dengan berat 1 g untuk setiap sampel. Seluruh sampel diekstraksi dengan prosedur standar dan diencerkan dengan perbandingan 1:70 (volume/volume). Sampel kopi yang telah diencerkan kemudian diambil sebanyak 3 mL, dimasukkan ke dalam sel kuvet kuarsa, dan diambil spektranya menggunakan alat spektrometer UV-visible (Genesys UV-visible   spectrometer, Thermo Fisher, Scientific, USA) di rentang panjang gelombang 190-400 nm dengan interval 1 nm. Hasil PCA spektra transformasi di panjang gelombang 250-400 nm menunjukkan tiga kultivar kopi spesialti arabika dan kopi robusta dapat dibedakan dengan jelas dan terletak di klaster yang berbeda. Namun kopi spesialti arabika Typica dan Sigarar Utang terletak di klaster yang saling berdekatan dan sebagian sampel saling bertumpuk menunjukkan kedua kultivar kopi arabika tersebut memiliki kemiripan. Hasil PLS-DA spektra transformasi di panjang gelombang 250-400 nm menunjukkan model klasifikasi yang dibangun dapat digunakan untuk klasifikasi kopi robusta dan kopi arabika dengan tiga kultivar berbeda (Typica, Sigarar Utang, dan Yellow Bourbon) dengan akurasi klasifikasi mencapai 97.8 sampai 100%. Hasil ini menunjukkan potensi penggunaan metode spektroskopi UV untuk autentikasi cepat kopi spesialti arabika Java Preanger Typica, Sigarar Utang, dan Yellow Bourbon.
Aplikasi Etilen Absorber Untuk Menunda Kematangan Dan Dampaknya Terhadap Eating Quality Pisang Mas Kirana (Musa Sp.AA Group)
Authors: Lita Trialita aprilia , Sutrisno  , Emmy Darmawati
Published: April 2023

Pisang Mas Kirana merupakan salah satu varietas pisang yang menjadi penopang utama industri dan perdagangan pisang dalam negeri maupun ekspor. Umur simpan pisang yang pendek sangat tidak menguntungkan bagi komoditas pertanian yang membutuhkan waktu distribusi yang lama untuk sampai ke tangan konsumen. Hal inilah yang menjadi kendala utama ekspor buah Indonesia ke mancanegara. Salah satu cara untuk menjaga mutu buah pisang selama pengangkutan, pendistribusian dan penyimpanan adalah dengan mempertahankan umur hijaunya atau menunda proses pemasakan sesuai dengan distribusi pasar baik dalam negeri maupun ekspor. Proses pemasakan pisang dapat diperlambat (menjaga hijau hidup) dengan menggunakan penyerap etilen berbahan Zeolit-KMnO4, yang berfungsi untuk menahan produksi etilen pada buah klimakterik. Etilen Adsorber Bag (EAB) diaplikasikan pada pisang Mas Kirana yang dikemas dengan berat pisang 1.000±50 g. EAB dikeluarkan dari kemasannya dan pisang dibiarkan pada suhu kamar untuk pematangan alami sampai ditampilkan. Hasil penelitian menunjukkan bahwa aplikasi EAB mampu mempertahankan umur hijau pisang sesuai skenario umur simpan baik pada suhu ruang (27±2oC). Proses pematangan alami memakan waktu 2-3 hari setelah EAB dirilis untuk semua skenario. Lama waktu sampai panelis tidak menerimanya adalah 18-25 hari untuk penyimpanan suhu ruang, sedangkan penyimpanan ruang kontrol mencapai 12 hari.
Cultural and legal phenomenon of V.G. Baev (in memory of the scientist, teacher and social activist)
Authors: Sadokhina Nataliya E.
Published: April 2023

The main stages of the life path of Doctor of Law, Candidate of Historical Sciences, Professor Valery Grigoryevich Baev are highlighted. His contribution to the development of education in the Tambov region was noted both in the course of scientific, pedagogical activities, and as a result of administrative work in state and local government bodies. Attention is paid to the applied V.G. Baev pedagogical methods based on the interactive format of the relationship between the teacher and the student, the involvement in the educational process of the most prominent representatives of practical jurisprudence, as well as Russian and foreign scientists, the use of works of fiction and cinematographic art to discuss ethical issues of professional activity of a lawyer. In particular, it was noted that practical classes became a platform for scientific discussions, as well as discussions of ethical problems of the legal profession, when each student in the group was a participant in them, and the axiological approach to the study of law formed an awareness of its unconditional authority and significance, which happened through acquaintance with the world masterpieces of domestic and foreign literature and cinematography, helped education of a comprehensively developed personality. The scientific works of the scientist devoted to the peculiarities of German constitutionalism of the second half of the 19th – first half of the 20th century are analyzed.
Characteristics and Clinical Profile of Vitiligo Patients in Dermatology and Venereology Outpatient Clinic Unit at Dr. Soetomo General Academic Hospital Surabaya
Authors: Arifin Saiboo Alvian , Sigit Prakoeswa Cita Rosita , Indramaya Diah Mira , Hidayati Afif Nurul , Damayanti  , Rahmadewi  , Utomo Budi , Eliza Frizka
Published: April 2023

Background: Vitiligo is a depigmentation disorder characterized by the progressive loss of melanocytes from the epidermis and hair follicles. Vitiligo affects all age groups and is defined by acquired, idiopathic, progressive, different-sized, circumscribed, milky white depigmentation. Characteristics and clinical patterns of vitiligo will also help to understand the pathogenesis of the disease. Purpose: The aim of this study is to evaluate the characteristics profile and clinical features of vitiligo patients. Methods: The research material was taken from the medical record of vitiligo patients in the Division of Cosmetics Outpatient Clinic Dermatovenerelogy Dr. Soetomo General Hospital Surabaya from 2018-2020. Result: This study was obtained by a number of new vitiligo patients 115 (0.3%) of the total number of new outpatient clinic visits of Dermatovenereology Dr. Soetomo General Hospital Surabaya. The majority of the gender is female (53.9%), late adolescence (26.96%), students (25.22%), and the onset of vitiligo 1-5 years (30.43%). The most common risk factors were idiopathic (51.3%) and clinical types are non-segmental vitiligo (53.04%). Conclusion: Vitiligo predominantly affects in females with active age groups of 17-25 years old, and students.
Evaluation of Histopathology Findings of Clinically Confirmed Psoriasis Vulgaris
Authors: Sawitri  , Fadila Arisia , M. Yulianto Listiawan  , Priangga Adi Wiratama  , Dwi Murtiastutik  , Evy Ervianti  , Linda Astari  , Damayanti  , Diah Mira Indramaya  , Afif Nurul Hidayati  , Medhi Denisa Alinda
Published: April 2023

Background: Psoriasis vulgaris can be diagnosed clinically. A biopsy is usually used to confirm non-classic cases. The findings of the histopathology feature are not usually present, thus clinical relevance is needed to confirm the diagnosis. Purpose: To describe the histopathology findings from tissue samples of histopathologically confirmed psoriasis vulgaris reported in the Department of Pathology and Anatomy of Dr. Soetomo General Hospital. Methods: A descriptive-retrospective study of pathology-ascertained tissue samples of histopathologically confirmed psoriasis vulgaris was reported in the Department of Pathology and Anatomy from patients who were also previously diagnosed clinically with psoriasis vulgaris in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital over a period of 2 years. Morphological parameters were observed after histopathology sections were stained with hematoxylin and eosin. Result: Thirty-three tissue samples were examined. Parakeratosis (86%) and hypogranulosis (70.3%) were the most observed findings. Club-shaped rete ridges, suprapapillary plate thinning, and spongiform pustules of Kogoj were the least observed findings (each by 2.7%). Three tissue samples (8.1%) showed only parakeratosis. Only 1 tissue sample (2.7%) showed 4 features (absence of the granular layer, parakeratosis, microabscess of Munro, and spongiform pustules of Kogoj). No tissue sample showed every histopathology finding of psoriasis vulgaris. Conclusion: All of the histopathology features of psoriasis vulgaris are rarely found in one tissue section. Albeit histopathology is believed to be the gold standard diagnosis of psoriasis vulgaris, relevance with clinical findings is still mandatory to support the diagnosis.
Retrospective Study of Decubitus Ulcer in Hospitalized Patients
Authors: Rosmarwati Ervina , Mulianto Nurrachmat
Published: April 2023

Background: Decubitus ulcer is an area of necrotic tissue due to compression of protrusion because of prolonged immobilization. Decubitus ulcer is complication that often occur due to prolonged bed rest. Decubitus ulcer can interfere with patient’s recovery process and prolonged hospital stay.  Purpose: To investigate profile of decubitus ulcer in hospitalized patients in Dr. Moewardi General Hospital Surakarta during 2017- 2020. Methods: This descriptive retrospective study was conducted by using medical record of decubitus ulcers (ICD 10 L89.0, L89.1, L89.2, L89.3) in Dr. Moewardi General Hospital Surakarta during 1st January 2017-31st December 2020. Result: There were 375 decubitus ulcer patients, mostly aged 70 years or more (29.1%) and dominated by women (56%). Patients with decubitus ulcers often hospitalized in the regular ward (75.2%) with the longest length of stay being around 0-10 days (49.6%) and the most common comorbidities was malignancy (20.5%). Systemic antibiotic ceftriaxone was most often given to decubitus ulcer patients (21.6%). Most of the patients with decubitus ulcers had stage 2 decubitus ulcers (53.6%) with a predisposition to the affected area being the sacrum area (33%). The most frequently used therapy for decubitus ulcers was hydrogel dressing (33.9%). Conclusion: Decubitus ulcers are often found in patients over 70 years of age with comorbid malignancies. The most common diagnosis was stage 2 decubitus ulcers, predisposing to the sacral region and the most frequently used therapy was hydrogel dressing with ceftriaxone as a systemic antibiotic.
The Clinical Profile of Patients with Chronic Wounds at Dr. Soetomo General Hospital 2015-2020
Authors: Budirahmadina Nurvania aurellia , Perdanakusuma David sontani , Ervianti Evy , Saputra Iswinarno doso
Published: April 2023

Background: Wounds that have lasted a long time due to failure to continue the normal healing process can be called chronic wounds. Chronic wounds occur due to multiple factors. There are problems that are often found in chronic wounds, such as the presence of exudate, necrotic tissue, and bacteria. The incidence of chronic wounds is closely related to the high cost of treatment and impaired quality of life. Prompt wound management is needed to optimize wound healing. Purpose: To determine the profile of chronic wounds in patients treated by the Department of Plastic Surgery Dr. Soetomo General Hospital Surabaya from 2015 – 2020. Methods: The data were obtained from patients medical records through total sampling technique, which consist of age,   gender, past medical history, clinical features, diagnosis, management, and outcome. Result: This study involved 53 patients, dominated by male patients (70%) aged 46-65 years old (34%). The patient’s history showed that most patients suffered from type 2 diabetes (22%). The problem that often occurs is the presence of exudate which is mostly diagnosed with pressure ulcers (40%). All patient get wound bed preparation and the patient's outcome was dominated by recovery (72%). Conclusion: There are several factors affecting wound healing and prompt wound management are important to improving the outcomes.
Chemical Peeling in Skin-Aging Patients: A Retrospective Study
Authors: Susanto Ester Chateline , Setyaningrum Trisniartami , Arifa Mustika  , Astari Linda
Published: April 2023

Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients’ medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients’ main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.
Henoch-Schonlein Purpura in Adult with Gastrointestinal and Renal Involvement
Authors: Devi Aprilin Krista , Umborowati Menul Ayu , Anggraeni Sylvia , Damayanti Damayanti , Prakoeswa Cita Rosita Sigit
Published: April 2023

Background: The pathogenesis of Henoch-Schonlein Purpura (HSP), a multisystem organ-involved small vessel vasculitis, is unknown. HSP is more common in youngsters than in adults. HSP is associated with a history of malignancies, medications, vaccinations, and upper respiratory tract infections. Painful purpura, arthritis, stomach discomfort, and renal involvement are symptoms that may be seen in HSP patients. Adult patients had a much higher rate of renal involvement than children. Purpose: To report a case of HSP in an adult with gastrointestinal and renal involvement. Case: A 45-year-old man complained of an arm, leg, and waist rash for two weeks before admission to the hospital. He also has stomach pains, nausea, and vomiting to deal with. His symptoms have just appeared now for the first time. During a renal function test, blood urea nitrogen (BUN) and creatine serum levels rose. On a urinalysis, proteinuria and microscopic hematuria were found. Leucocytoclastic vasculitis was discovered during the histopathology investigation. HSP diagnosis was based on the ACR and ICC criteria. The patient was given 3x2 tablets of 0.5 mg dexamethasone, 3x2 tablets of cetirizine, 2x10 mg lisinopril, 2x50 mg ranitidine injection, and 2 grams ceftriaxone. Discussion: The clinical symptoms of HSP are used to make the diagnosis. In the vast majority of instances, the treatment is only supportive therapy. Corticosteroid usually are usually used for HSP with multisystem organ involvement to reduce pain severity and faster resolution of renal manifestation. Conclusion: Follow up on renal function is needed to monitor the worsening of renal disease.