bluuebunny/crossref_metadata_2025 huggingface dataset:
Preterm birth risk in women with skeletal dysplasias and short stature
Authors: O’Connor Deirdre , Menzies Rebecca , Cao Xingshan , Berndl Anne
Published: December 2022

PURPOSE: The primary objective was to estimate the risk of preterm delivery in a population of women with a skeletal dysplasia and short stature. The secondary outcome was to identify factors that increase the risk of preterm delivery. METHODS: A cross sectional survey was performed asking detailed pregnancy and reproductive health questions, aimed at a convenience sample of women who were little people, administered through Little People of America, Little People UK, Little People Canada, and the World Dwarf Games. Comparisons were made on gestational age at delivery between pregnancies with and without the outcomes. RESULTS: The survey had a response rate of 74% (117/158). There was a total of 55 eligible subjects who had 72 live births. Delivery prior to 37 weeks occurred in 19/72 live births, which equates to a preterm birth rate of 26.4%. Besides short stature, no single factor was identified that could solely explain the elevated preterm birth risk in the study population. CONCLUSION: The risk of preterm delivery in women with skeletal dysplasias and short stature is elevated compared to the general population. This information will assist healthcare providers in pregnancy management and counseling.
The French National Council for Statistical Information: Lessons from a formal dialogue between producers and users on sustainable development
Authors: Anxionnaz Isabelle , D’Alessandro Cristina , Montus Arnaud , Tagnani Stéphane
Published: December 2022

Focusing on the French National Council for Statistical Information (Cnis), this paper offers an overview on the value and strength of the dialogue between producers and users of official statistics in France. Highlighting its specific contribution to shape official statistics in relation to sustainable development, it presents its role and original value added in the French context on a critical issue for the post-COVID era. If this case study proposes lessons to learn from this experience, its history, and transformation over time, it wants also to point out promising evolutions and paths for the future. In a context of crisis and pandemic, the need to produce quality and timely statistics adapted to the situation has showed its capacity to adapt and to confirm its critical role.
A novel method for conformity assessment testing of dialysis machines for post-market surveillance purposes
Authors: Badnjevic Almir , Deumic Amar , Biskovic Dusanka , Pokvic Lejla Gurbeta
Published: December 2022

BACKGROUND: Dialysis machines are used regularly in healthcare practice. They are classified as a type of medical device with moderate and high risk therefore significant requirements are placed on their safety and performance every time they are used on patients. The new Medical Device Regulation (MDR) defines medical device post-market surveillance (PMS) as performed by independent, third-party, notified bodies more strategically in hope to improve traceability of device performance. However, there is still an apparent gap in terms of standardised conformity assessment testing methods. OBJECTIVE: This paper proposes a novel evidence-based method for conformity assessment testing of dialysis machines for post-market surveillance purposes. METHOD: The novel method is developed according to the International Organisation of Legal Metrology (OIML) guidelines and is to be used for the purpose of conformity assessment testing of Dialysis machines with respect to their metrological characteristics during PMS. RESULTS: The developed method was validated between 2018 and 2021 in healthcare institutions of all levels. The results obtained during validation suggest that conformity assessment testing of dialysis machines as a method used during PMS contributes to significant improvement in devices’ accuracy and reliability. CONCLUSION: A standardized approach in conformity assessment testing of dialysis machines during PMS, besides increasing reliability of the devices, is the first step in digital transformation of management of these devices in healthcare institutions opening possibility for use of artificial intelligence.
A novel method for conformity assessment testing of infant incubators for post-market surveillance purposes
Authors: Badnjevic Almir , Spahic Lemana , Jordamovic Naida Babic , Pokvic Lejla Gurbeta
Published: December 2022

BACKGROUND: Premature born infants or infants born sick require immediate medical attention and decreasing the stress imposed onto their body by the environment. Infant incubators provide an enclosed environment that can be controlled to fit the needs of the infant. As such, their performance must be consistent and without significant deviations. The only manner to ensure this is by post-market surveillance (PMS) focused on evaluation of both safety and performance. The new Medical Device Regulation (MDR) defines medical device post-market surveillance (PMS) as performed by independent, third-party, notified bodies more strategically in hope to improve traceability of device performance. However, there is still an apparent gap in terms of standardised conformity assessment testing methods. OBJECTIVE: This paper proposes a novel method for conformity assessment testing of infant incubators for post-market surveillance purposes. METHOD: The method was developed based on guidelines for devices providing measurements laid out by the International Organisation of Legal Metrology (OIML). The methodology was validated during a four year period in healthcare institutions of all levels. RESULTS: The developed method was validated between 2018 and 2021 in healthcare institutions of all levels. The results obtained during validation suggest that conformity assessment testing of infant incubators as a method used during PMS contributes to significant improvement in devices’ accuracy and reliability. CONCLUSION: A standardized approach in conformity assessment testing of infant incubators during PMS, besides increasing reliability of the devices, is the first step in digital transformation of management of these devices in healthcare institutions opening possibility for use of artificial intelligence.
The effects of acute normobaric hypoxia on vestibular-evoked balance responses in humans
Authors: Debenham M.I.B. , Grantham T.D.A. , Smirl J.D. , Foster G.E. , Dalton B.H.
Published: December 2022

BACKGROUND: Hypoxia influences standing balance and vestibular function. OBJECTIVE: The purpose here was to investigate the effect of hypoxia on the vestibular control of balance. METHODS: Twenty participants (10 males; 10 females) were tested over two days (normobaric hypoxia and normoxia). Participants stood on a force plate (head rotated leftward) and experienced random, continuous electrical vestibular stimulation (EVS) during trials of eyes open (EO) and closed (EC) at baseline (BL), after 5 (H1), 30 (H2) and 55-min (H3) of hypoxia, and 10-min into normoxic recovery (NR). Vestibular-evoked balance responses were quantified using cumulant density, coherence, and gain functions between EVS and anteroposterior forces. RESULTS: Oxyhemoglobin saturation, end-tidal oxygen and carbon dioxide decreased for H1-3 compared to BL; however, end-tidal carbon dioxide remained reduced at NR with EC (p≤0.003). EVS-AP force peak-to-peak amplitude was lower at H3 and NR than at BL (p≤0.01). At multiple frequencies, EVS-AP force coherence and gain estimates were lower at H3 and NR than BL for females; however, this was only observed for coherence for males. CONCLUSIONS: Overall, vestibular-evoked balance responses are blunted following normobaric hypoxia >30 min, which persists into NR and may contribute to the reported increases in postural sway.
Disorders of endothelium-dependent vasodilation in patients with microvascular angina
Authors:   I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation, Leonova I.A. , Zakharova O.V. ,   I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation, Boldueva S.A. ,   I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation
Published: December 2022

Background: disorders of both endothelium-dependent and endothelium-independent vasodilation play a role in the pathogenesis of microvascular angina (MVA), the contribution of which may be different. Aim: to study the processes of endothelium-dependent vasodilation (EDV) in patients with primary MVA. Patients and Methods: an open prospective study included 60 patients (mean age 57.3±6.4 years) with MVA, confirmed clinical picture (chest pain), coronary angiography data (the absence of coronary artery stenosis), positive stress test (pain syndrome and/or ST segment depression by ≥2 mm by treadmill exercise stress test), positron emission tomography (PET) myocardial perfusion imaging (MPI) with tests (cold pressor test and with adenosine). Patients with diseases that can lead to secondary microvascular dysfunction were not included in the study. To evaluate the processes of EDV, all patients underwent the following evaluations: peripheral arterial tonometry (PAT), assessment of circulating endothelial cells (CEC), high-sensitivity C-reactive protein (hsCRP), endothelin-1 (ET-1), total antioxidant status. Adding that, the results of a cold pressor test during PET were analyzed. Results: the majority of the examined patients were women — 81.7%. Most of the female patients included in the study (93.9%) were postmenopausal. In all patients with MVA, according to the data of PET MPI with cold pressor test, signs of EDV disorder were detected as a decrease in coronary blood flow through the three coronary arteries. During PET, the index of reactive hyperemia was reduced (<1,67) in all examined patients and amounted to 1.43±0.15. According to the results of laboratory studies, there was an increase in the level of ET-1 and CEC — 3,335 [1,545; 3,952] fmol/L and 14±8 cells/3×105 leukocytes, respectively. The CRP level was 4,44 [1.02; 4.45] mg/L. The total antioxidant capacity was reduced in 53 (88%) patients, the average values of the indicator were 289,03±52,14 μmol/L. Conclusion: according to laboratory and instrumental studies, signs of endothelial dysfunction, namely disorders of EDV, were revealed in all examined patients with primary MVA. KEYWORDS: microvascular angina, peripheral arterial tonometry, endothelium-dependent vasodilation, positron emission tomography. FOR CITATION: Leonova I.A., Zakharova O.V., Boldueva S.A. Disorders of endothelium-dependent vasodilation in patients with microvascular angina. Russian Medical Inquiry. 2022;6(8):427–432 (in Russ.). DOI: 10.32364/2587-6821-2022-6-8-427-432.
Experience with the use of potassium and magnesium aspartate in the treatment of cardiovascular diseases
Authors:   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Yalymov A.A. , Efremova Yu.E. ,   Acad. E.I. Chazov National Medical Research Center of Cardiology, Moscow, Russian Federation, Shekhyan G.G. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation, Charaeva T.G. ,   M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation
Published: December 2022

The article discusses the efficacy and safety profile of potassium and magnesium aspartate agents in the treatment of patients with cardiovascular diseases (CVD). The data demonstrate that potassium and manganese deficiency play an important role in the etiology of CVD and the increased mortality. Hypokalemia and hypomagnesemia are frequently reported in patients with cardiological disorders. The article elucidates the results of multi-center randomized trials in patients with CVD (arterial hypertension, ischemic heart diseases, and cardiac arrhythmia). Also, the article presents two clinical cases with the successful use of potassium and magnesium aspartate (Panangin®, Gedeon Richter) in the treatment of cardiovascular complications associated with electrolyte imbalance. Based on the results of multiple studies involving CVD patients it is suggested that the addition of potassium and magnesium aspartate to the essential therapy improves the effectiveness of CVD management. Thus, potassium and magnesium aspartate can be recommended to cardiac patients. KEYWORDS: potassium and magnesium aspartate, Panangin, hypomagnesemia, hypopotassemia, arterial hypertension, ischemic heart disease, myocardial infarction, prolonged QT interval, cardiac arrhythmias, ventricular tachycardia. FOR CITATION: Yalymov A.A., Efremova Yu.E., Shekhyan G.G., Charaeva T.G. Experience with the use of potassium and magnesium aspartate in the treatment of cardiovascular diseases. Russian Medical Inquiry. 2022;6(8):433–442 (in Russ.). DOI: 10.32364/2587-6821- 2022-6-8-433-442.
Chondroprotective therapy of osteoarthritis: a tribute to tradition or a proven necessity?
Authors:   Institute of Integrative Family Therapy, Moscow, Russian Federation, Egorov I.V.
Published: December 2022

The study of cellular and molecular patterns of osteoarthritis (OA) shows that, since the key sign of the disease is progressive cartilage loss, today it is considered as a spectrum of conditions affecting all joint tissues. The disease is based on special tissue mechanisms: some of them are unique to a single tissue, and some are common to several tissues and joints. Recent studies allowed to identify individual subtypes of OA, depending on the development of pathological changes in certain tissue: bone tissue, articular cartilage, inflammation or changes in the synovial membrane. Therefore, chondroprotection requires a holistic approach, stratification of patient groups and achievement of their respective final goals. Given the past therapeutic experience (including unsuccessful), it is necessary to develop medicinal products using modern technologies and the latest knowledge. The main aim of chondroprotection is to provide the suitable treatment to the appropriate patient at the right time. Despite the abundance of new technologies and pharmacological developments, European experts still recommend a combination of chondroitin sulfate and glucosamine as the treatment of choice at the initial stage of OA. KEYWORDS: chondroprotection, osteoarthritis, treatment tactics, development of medicinal products, chondroitin sulfate, glucosamine. FOR CITATION: Egorov I.V. Chondroprotective therapy of osteoarthritis: a tribute to tradition or a proven necessity? Russian Medical Inquiry. 2022;6(8):480–485 (in Russ.). DOI: 10.32364/2587-6821-2022-6-8-480-485.
The Polyfollicular Anovulatory Androgenic Syndrome: A New Label for an Old Syndrome
Authors: Kandil Mohamed
Published: December 2022

Polycystic ovary syndrome is a hormonal disorder common among women of reproductive age. The affected women may have infrequent or prolonged menstrual periods or excess male hormone levels with manifestations of hyperandrogenemia. The ovaries may fail to ovulate with many arrested follicles at the primordial stage. There was a time when the medical profession honored its members by naming diseases after them and that was the case with Stein and Leventhal syndrome which was later changed to polycystic ovary syndrome. Since then, our understanding of the syndrome had changed dramatically. It is now not just a mere association of symptoms with some ultrasonographic features, but rather complex hormonal and metabolic abnormalities with a wide spectrum of variable clinical presentations. Hence, there is an obvious need for a new name to reflect these abnormalities. This article explains the existing problem with the current name and suggests a new system to rename the syndrome.
New Terms for the Educators’ Digital Lexicon
Authors: Gilbert Gregory E. , Bauman Eric B.
Published: December 2022

In 2001 Prensky introduced the terms “digital immigrant” and “digital native”. While some may argue these terms are now considered historical, we argue that they are and remain culturally significant and historically timeless.  As such we use them to frame our discussion here as it relates to the introduction of new terms salient to higher education. Currently the educators' digital lexicon is insufficient to address educational success. The authors present terms augmenting the educators’ digital lexicon. The authors propose terms expanding the digital lexicon including another class of learner – the digital Neanderthal and terms for educators to consider including digital concordance, digital discord, digital disruption, and digital dissonance. These terms are a result of members of each digital class not considering their learners. Unless instructors adopt learning theories amenable to appropriate classes of learners in the digital landscape, they will be barriers to learning instead of facilitators. If students are taught without regard to their digital demographic, educators will lose a vital opportunity to engage students regardless of their digital demographic. Administrators must also consider the faculty digital demographic when implementing technical innovations as this demographic may impact its success or failure. The authors are unaware of other work highlighting or conceptualizing this new class of learner or educator. Further, to our knowledge we are unaware of the concepts presented here being presented elsewhere. The consideration of these concepts is critical to the success of students today in the future and our educational institutions.
Efectos de un programa de educación física con frecuencia dos veces por semana sobre la fuerza, resistencia aeróbica y flexibilidad de extremidad superior en alumnos de séptimo año básico
Authors: Fuentes Flores Fabián
Published: December 2022

Objetivo: el objetivo del estudio fue determinar el efecto que tienen las clases de Educación Física con frecuencia de dos por semana, sobre la condición física de los alumnos de séptimo año básico, valorado a través de la fuerza-resistencia, potencia, resistencia aeróbica y flexibilidad miembros inferiores. Metodología: la muestra corresponde a 66 alumnos de la escuela número 1 Nuestra Señora del Tránsito de la comuna de Molina. El grupo control (GC) estuvo compuesto de 33 y otros 33 fueron parte del grupo experimental (GE). La obtención de los datos fue a través de un proceso que incluyó, firma de consentimiento informado a los estudiantes y las mediciones de peso, talla, edad, IMC y encuesta de la actividad física (IPAQ), además, se aplicaron las evaluaciones de la condición física, test de flexiones de brazos, test de flexión de tronco, test de salto largo, test de abdominales cortos y test de Cafra. El plan de intervención tuvo una duración de ocho semanas, una sesión de noventa minutos por semana para el grupo control (GC) y dos sesiones de 45 minutos para el grupo experimental (GE) Resultados: para el GE se obtuvo diferencias significativas en las variables cantidad de abdominales (p = 0,00), salto largo (p = 0,001) y test de Cafra (p = 0,001) mejora significativa, corresponde a la evaluación intragrupo Conclusión: La realización de clases de educación física presentaría una mejora de la capacidad física en algunos indicadores como cantidad de abdominales, salto largo y capacidad aeróbica.
PERANCANGAN SMART TRASH PENDETEKSI SAMPAH LOGAM DAN NON LOGAM BERBASIS ARDUINO UNO
Authors: Wahyudi Dedi
Published: December 2022

Kemajuan teknologi khususnya di bidang mikrokontroler dan sensor sangat berdampak besar pada kehidupan manusia. Misalnya dalam bidang kebersihan, pemilahan sampah secara otomatis harus dilakukan, karena saat ini masyarakat kurang mendapat informasi tentang lingkungan terutama tentang pembuangan sampah. Pemilahan sampah bertujuan untuk memilah sampah, dalam hal ini menjadi logam dan non logam, sehingga proses daur ulang sampah menjadi lebih efisien. Namun pada kenyataannya, jenis sampah masih tercampur di tempat pembuangan akhir. Berdasarkan permasalahan tersebut, dibuatlah otomatisasi tempat sampah, sebuah prototipe tempat sampah cerdas berbasis mikrokontroler yang fungsi utamanya adalah untuk memilah sampah khususnya sampah yang mengandung unsur logam. Secara keseluruhan perancangan alat ini berhasil dilakukan. Hal ini dapat dibuktikan dengan hasil pengujian dari total 36 (tiga puluh enam) responden 28(78%) responden menjawab sistem sangat menarik, 27(75%) responden menjawab sistem sangat mudah untuk digunakan, 30(83%) responden menjawab kinerja sistem sangat baik, dan 33(92%) responden menjawab sistem sangat bermanfaat.
Meaning in Life of Medical Sciences Students During COVID-19 Outbreak: A Cross-sectional Study
Authors:   Department of Islamic Theology, Yadegar-e-Imam Khomeini, Shahr-e Rey Branch, Islamic Azad University, Tehran, Iran., Mahdavinoor Seyyed Muhammad Mahdi , Mollaei Aghil ,   Department of Islamic Theology, Yadegar-e-Imam Khomeini, Shahr-e Rey Branch, Islamic Azad University, Tehran, Iran., Mahdavinoor Seyyed Hatam ,   Department of Islamic Theology, Yadegar-e-Imam Khomeini, Shahr-e Rey Branch, Islamic Azad University, Tehran, Iran.
Published: December 2022

Background and Purpose: The outbreak of coronavirus and its subsequent conditions have affected the mental health of students. One of the variables related to mental health is “meaning in life.” It enables students to endure sorrows and hardships to survive extremely difficult living conditions. Meaning in life is also inversely related to suicide and mental disorders. In this study, we intend to assess the meaning of life among students of Tehran University of Medical Sciences, Tehran City, Iran. Materials and Methods: In this cross-sectional study, 208 students participated. We used an internet-based data collection method between September 12 and September 24, 2021, to collect the study data. The data collection tool was a valid and reliable questionnaire concerning meaning in life. The obtained data were analyzed using descriptive (frequency, mean, standard deviation) and inferential (Fisher exact-test, independent t-test, and 1-way analysis of variance) statistics. Results: Among the samples, there were 146 females (70.2%). The Mean±SD age of the participants was 21.50±2.74 years. The results showed that nearly 95% of students had neither meaning in life nor were looking for a meaning that would give value to their lives. Conclusion: The results of this study indicate the catastrophe that prevails among students. When students have no meaning in life and do not look for meaning, they are highly vulnerable to psychological injuries. This condition is the worst psychological state a person can experience, which could lead to a feeling of depression and higher suicide risk. Health policymakers need to think about resolving the lack of “meaning in life” among students as soon as possible.
The Effects of 6 Weeks of Balance Training on Static and Dynamic Balance of Blind Students
Authors:   Department of Sport Sciences, Faculty of Humanities and Social Sciences, Yazd University, Yazd, Iran., Abbasi Hamid , Esfandiyari Ghalesorkhi Zeinab ,   Department of Sport Sciences, Faculty of Humanities and Social Sciences, Yazd University, Yazd, Iran., Sharifatpour Reza ,   Department of Sport Sciences, Faculty of Humanities and Social Sciences, Yazd University, Yazd, Iran., Abedinzadeh Saeed ,   Department of Sport Sciences, Faculty of Humanities and Social Sciences, Yazd University, Yazd, Iran.
Published: December 2022

Background and Purpose: Visual disturbance causes problems in the orientation, balance, and movement of individuals. It is especially important in children because this is a golden age for adoring physical exercises and physical function in these people. Therefore, this study aimed to evaluate the effect of 6 weeks of balance training on the static and dynamic balance of blind students. Materials and Methods: This is a quasi-experimental study, and the subjects included 45 blind students living in Ahwaz City, Iran. The participants were selected using convenience and purposive sampling methods. A sample of 20 girls and 20 boys, aged 7-14 years, was selected and randomly divided into two control and experiment groups consisting of 20 subjects each (10 females and 10 males). The experimental group received a six-week course of balance training intervention. They have received six-week balance training program, 2 sessions of 45 minutes a week. Static balance was measured by stork test and for dynamic balance star balance test was used. The Shapiro-Wilk test was used to control the normality of data. In order to study the effect of time and between groups, repeated measures ANOVA was used. For analyzing the data SPSS software, version 25, Excel 2019 software, and in all statistic test α=0.05 was used. All analyses were done in SPSS software v. 25, Excel 2019 software. The significance level was considered at 0.05 for all tests. Results: The two groups of blind student, each groups 20 subjects and mean age of 10.33 and 11.12 years in control and exercise group respectively. Comparing the groups showed that six weeks of balance training had a positive and significant effect on static balance and dynamic balance of exercise group (P<0.001). The results also showed that in the Post-test stage, the experimental group performed better in static and dynamic balance in all 8 directions compared to the control group (P<0.001). There was no significant difference between girls and boys in terms of balance. Conclusion: Regarding the effect of these exercises on improving the balance of blind children, it is recommended that parents, physical education teachers, occupational therapists, physiotherapists, and all those who are in some way associated with these children, use balance training as a therapeutic plan.
Pengaruh kualitas produk, diskon harga, dan Promosi terhadap keputusan pembelian
Authors: Herdian Risma , Puspitasari Devy M.
Published: December 2022

Competition between retail store owners is now unavoidable because many companies are competing to increase market share and reach new customers. This study aims to determine the effect of product quality, discounts, and promotions on purchasing decisions: an empirical study on Griya Department Stores. The method used in this study is multiple regression analysis. The data used is primary data collected through collecting questionnaires from 100 Griya Department Store customers. Empirical investigations show that product quality and promotional power have a strong influence on purchasing decisions. While the price discount has no relationship with the purchase decision, Good product quality accompanied by proven promotional power strengthens the customer's decision to buy. High price discounts do not always affect the customer's decision to buy the product. This research is useful for encouraging department store management to pay attention to their promotions so that they are right on target and reach their market. Excellent product quality, management must pay attention to give customers confidence that they are purchasing from the right place.
Pengaruh kompetensi pengguna sistem informasi akuntasi terhadap kualitas informasi akuntansi
Authors: Maulana Fajar
Published: December 2022

In this era of globalization, information can be interpreted as data that is processed and managed with the intention of giving meaning and helping the decision-making process. This study intends to examine the effect of the variable ability of AIS users (Accounting Information Systems) on the variable quality of accounting information. This research is quantitative and uses descriptive and verification methods using survey techniques. The researcher used nonprobability sampling with saturated sampling, with 30 accounting and system employees from PT. ABC and XYZ, both food and beverage industry companies in Bandung Regency, as samples and respondents. The data analysis technique uses simple linear regression with a questionnaire data collection technique. The results of this study concluded that there is a significant influence between the competency variables of accounting information system users (AIS) and the quality of accounting information.
Cultivation of commercial carp in fisheries LLC “Mykolaivska RMS” with use in its feeding feeds of the trademark “Reucher AQUA fish”
Authors: Senechyn V. V. , Oseredchuk R. S. , Yakimova E. O.
Published: December 2022

The question of the effectiveness of domestic extruded compound feed in feeding carp fish was studied - as one of the methods of complex intensification of commercial fish production technology in the conditions of an individual fishery. The importance of studying this issue is dictated by the harsh realities of today, which are caused by the global trends of growing deficits in food products, among which a large share is occupied by fish and fishery products. The increase in demand for high-quality agricultural products and their prices is due to the crisis phenomena in the world economy, caused to some extent by long-term quarantine restrictions on all continents of the planet and the war in Ukraine. The purpose of the work was to study the technological processes of feeding in the cultivation of commercial carp and search for optimal methods for their improvement. To achieve this goal, the following tasks were performed: chemical and hydrobiological parameters in pond water were investigated; linear growth rate, weight growth rate, and carp fattening rate were analyzed; the fishery and economic indicators of the farm “Mykolaivska RMS” were analyzed. In two experimental ponds of the farm, they studied the peculiarities of growing carp fish when feeding them with domestic granulated compound feed with an optimal ratio of nutrients and biologically active substances while systematically determining the hydrochemical and temperature regimes of the experimental ponds, studying the morphometric indicators of two-year-old carp, calculating the fish productivity of the ponds of the farm and economic efficiency use of Reucher Aqua “Carp” feed. The obtained results confirm the effectiveness of using dry water-resistant extruded feed for feeding carp fish, which is manufactured according to modern technologies: it does not decompose in water for a long time. Therefore it does not change its quality and color; balanced in terms of the primary nutrients and biologically active substances, which positively affects the growth and development of fish, quality, and taste indicators of their meat. The use of this feed in a complex of intensification measures to improve technological processes in fish farming will allow obtaining a significant production and economic effect.
Productivity and hematological parameters of blood of young pigs at fatten-ing for feeding protein vitamin mineral supplement
Authors: Syrovatko K. M.
Published: December 2022

The article presents data on the productivity and hematological parameters of the blood of young pigs for fattening for the inclusion in their diet of a new protein vitamin-mineral supplement with essential oils, Efiprot. Plant essential oils are natural phytobiotics containing fat-soluble vitamins, polyunsaturated fatty acids, volatile acids, aldehydes, and other biologically active substances with bactericidal and antiseptic properties, increased appetite, and secretion of digestive juices. Thus, they provide better feed conversion and increased productivity. Protein vitamin-mineral supplement Efiprot is for a diet consisting of barley grains (50 %) and wheat grains (35 %). The experiment was carried out on two groups (12 heads in a group) of young pigs, a cross of Large White and Landrace. At the beginning of the experiment live weight of the animals was 35 kg; at the end, it was 110 kg. Control group animals were fed a supplement without essential oils; experimental group animals were additionally fed a dose of essential oils (200 g per 1 ton of supplement). Feeding supplements with essential oils positively affected pig productivity and feed growth. The absolute increase in live animals of the experimental group averaged 68.6 kg, average daily was 762 g; the corresponding values of the control group were 63.8 kg and 709 g for 90 days. Feeding protein vitamin-mineral supplement (PVMS) increased average daily gain by 53 g or 7.48 %, while feed consumption per 1 kg of live weight gain was lower by 0.3 energy feed units or 6.69 % than the control one. Hematological parameters of pig blood fed by PVMS Efiprot corresponded to the limits of the physiological norm. At the end of the experiment, an increase in erythrocytes, total protein, and hemoglobin was observed in the blood of the experimental animals, which is consistent with an increase in meat productivity. A slight increase in the mass of basophils, eosinophils, and leukocytes is adaptive and incredible.
Microscopic changes in some organs of cats at the infectious peritonitis
Authors: Lisova V. V. , Kotlyarov E. S.
Published: December 2022

The study's relevance is that pathomorphological changes in the infectious peritonitis of cats have been studied by a few authors and still need to be fully described. This paper describes the microscopic changes in the brain and spinal cord, liver, and somatic and visceral lymph nodes in cats with infectious peritonitis. The leading research method is a histological examination of sections obtained from the listed organs of cats of various ages that died from mixed (26 animals) and dry (7 animals) forms of infectious peritonitis. Sections were stained with hematoxylin and eosin according to the generally accepted method. It was found that microscopic changes in the brain and spinal cord do not depend on the form and duration of the disease. Gray and white matter are swollen, blood vessels are spasmodic, and nerve cells are in basophilia. A particularly significant swelling was found in the white matter of the spinal cord, which at the same time underwent lysis. In the liver, microscopic changes do not depend on the disease's form but are somewhat different depending on the duration of its course. In cats that were ill for less than three weeks before death, fibrinous-necrotic overlays are found on the surface of the capsule in places. Areas where mesotheliocytes of the capsule undergo metaplasia, are also seen – they acquire a cubic or columnar shape. In some places, the liver capsule is destroyed. The portal tracts are swollen and infiltrated with a small number of lymphocytes and monocytes, and the walls of the arteries of the hepatic triad are necrotized. Foci of tissue necrosis of the portal tract are also detected. Veins and bile ducts are not differentiated. Liver lobules are infiltrated with lymphocytes and monocytes. Cell swelling and destruction of hepatocytes were established. In animals that were ill for more than three weeks before death, in addition to the changes typical for infectious peritonitis, portal hepatitis, edema, and disorganization of liver lobules, hydropic dystrophy, destruction, and necrosis of hepatocytes were found. Changes in the lymph nodes are individual and do not depend on the form and duration of the course of the disease. However, in all cases of the registry, there were foci of necrosis in the central part of lymphoid nodules and the paracortical zone.
Advances in the reconstruction of the Spider Tree of Life: a roadmap for spider systematics and comparative studies
Authors: Kulkarni Siddharth , Wood Hannah , Hormiga Gustavo
Published: December 2022

In the last decade and a half, advances in genetic sequencing technologies have revolutionized systematics, transforming the field as studying morphological characters; a few genetic markers have given way to genomic data sets in the phylogenomic era. A plethora of molecular phylogenetic studies on many taxonomic groups have come about, converging on, or refuting prevailing morphology or legacy-marker-based hypotheses about evolutionary affinities. Spider systematics has been no exception to this transformation and the interrelationships of several groups have now been studied using genomic data. About 50,500 extant spider species have been described so far, all with a conservative body plan, but innumerable morphological and behavioral peculiarities. Inferring the spider tree of life using morphological data has been a challenging task. Molecular data have corroborated many hypotheses of higher-level relationships, but also resulted in new groups that refute previous hypotheses. In this review, we discuss recent advances in the reconstruction of the Spider Tree of Life and highlight areas where additional effort is needed with potential solutions. We base this review on the most comprehensive spider phylogeny to date, representing 131 of the currently known 132 (99%) spider families. To achieve this sampling, we combined a legacy data set of six Sanger-based markers with newly generated and publicly available genome-scale data sets. We find that some inferred relationships between major lineages of spiders (such as Austrochiloidea, Palpimanoidea, Synspermiata, etc.) are robust across different classes of data. However, several surprising new hypotheses have emerged with different classes of molecular data. We identify and discuss the robust and controversial hypotheses and compile this blueprint to design future studies targeting systematic revisions of these problematic groups. We offer an evolutionary framework to explore comparative questions such as evolution of venoms, silk, webs, morphological traits, and reproductive strategies.
Conceptual issues of management of sectoral territorial differentiation of the region
Authors:   Market Economy Institute of RAS, Anishchenko Alesya N. , Usmanov Daler I. ,   Market Economy Institute of RAS,   Department of Economic Theory at the Financial University under the Government of the Russian Federation
Published: December 2022

The article presents the results of the study of theoretical and methodological aspects of the assessment of territorial differentiation of regional agricultural production, its essence and a set of conditioning indicators are clarified. The assessment of the functioning of agriculture in the Vologda region (26 municipal districts), including the results of a survey of heads of agricultural organizations, was carried out. In order to study the regional differentiation of agricultural production and determine growth points on the materials of the Vologda region for 2020, their typological groupings were performed (cluster analysis by the method of «averages» in the program package «STATISTICA 10») based on a set of 33 economic indicators characterizing the availability of resources and the results of production activities. As a result, four groups of districts were identified. The study, in general, deepens the systematic mapping of agricultural production development in rural areas, which will allow us in the future to develop a scientifically based set of directions, measures, tools of state management of agricultural production to smooth territorial differentiation, as well as to improve the logistics system. The practical significance of the conducted research is due to the empirical testing of its main provisions in terms of: development and implementation of a database (certificate of state registration of the database № 2021621269 dated 15.06.2021) for monitoring the level of territorial differentiation of agricultural production, designed for operational and objective decision-making in the management of regional sectoral policy. Also, the obtained research results, their scientific and practical significance, the universality of the methodological approaches and recommendations used were used as part of the adjustment of the State Program «Development of the agro-industrial complex and the consumer market of the Vologda Region» (certificate of implementation № 02-3783/21 dated 16.06.2021).
Industry 4.0 technologies – a factor contributing to the introduction of a circular economy to achieve sustainable development (review of foreign literature)
Authors:   Central Economics and Mathematics Institute of RAS, Yerznkyan Bagrat H. , Fontana Karine A. ,   Central Economics and Mathematics Institute of RAS
Published: December 2022

The purpose of the study is to consider the features of Industry 4.0 generated by modern intellectual, information and digital technologies and providing a higher level of production. However, the impact of Industry 4.0, including individual technologies on the industries of the circular economy and individual stages of the product life cycle has not yet been sufficiently studied. The research contributes to the expansion of the understanding of these processes. The subject of the study is the circular economy (as one of the most important concepts aimed at sustainable development) and Industry 4.0 technologies. Target groups. Decision-making bodies and stakeholders responsible for the development and implementation of modern technological solutions that take into account the social and environmental components of sustainable development of the country and regions, including in the sectoral context. This research may find a response in the scientific community. As a methodological tool, the method of analyzing the literature in this area is used, in particular, a comparative analysis of case studies, practical developments in the field under study. Results. The analysis of the processes associated with the introduction of Industry 4.0 technologies at various stages of the life cycle of products in the industry context and their impact on the transition to the circular economy is carried out. It is considered and confirmed that Industry 4.0 technologies have a wide range of effects to improve circulation, which in turn contributes to achieving sustainability by realizing economic, social and environmental benefits. The differences in the potential impact of Industry 4.0 technologies on the stages of the product life cycle, including in the industry context, are demonstrated. It is shown that understanding such an impact will allow using the advantages of Industry 4.0 technologies to achieve sustainability and will contribute to the strategic implementation of such technologies in the context of the transition to a circular economy. Conclusions. In order to take advantage of the benefits provided by Industry 4.0 technologies to achieve sustainability by influencing circulation processes, it is necessary to carefully assess the degree of technology impact on various stages of the product life cycle, including taking into account its industry affiliation. Recommended. The conclusions made indicate the need to continue research in this direction in the light of the emergence of new technologies generated by their continuous development and integration.
The contribution of small and medium-sized businesses in supporting the integrative security of the state
Authors:   Market Economy Institute of RAS, Zoidov Kobiljon Kh. , Belomestnov Viktor G. ,   East Siberian State University of Technology and Management, Bortalevich Svetlana I. ,   Market Economy Institute of RAS
Published: December 2022

The article reveals the problems of the contribution of small and medium-sized businesses in supporting the integrative security of socio-economic systems, shows the need to improve the efficiency of using the potential of small and medium-sized businesses, including through the accelerated inspiration of new development concepts in small and medium-sized businesses. Goal. The purpose of this article is to study and justify methodological approaches to ensuring the integrative security of the state using the potential of small and medium-sized businesses. Tasks. To consider approaches to integrated modeling of integrative security; to reveal the areas of efficiency of small and medium-sized businesses in the context of supporting integrative security; to determine the potential for the development of the contribution of small and medium-sized businesses in supporting integrative security; to form approaches to the inspiration of modern concepts of development in small and medium-sized businesses. Methodology. The methodology for studying the contribution of small and medium-sized businesses in supporting integrative security is based on a systemic and structural analysis, an evolutionary-institutional approach. Results. Approaches to integrated modeling of integrative security are formed based on the classical model of assessing «portfolio» security risks, the hyper connection model of the components of security elements and the model of using integral reconciliation of indicators. The areas of efficiency of small and medium-sized businesses in the context of ensuring integrative security are disclosed. Special attention is paid to small innovative enterprises. The potential for the development of small and medium-sized businesses in ensuring integrative security, including: the potential of an ecosystem association based on integration, – clustering and associative cooperation; outsourcing potential; competition and cooperation potential; strategic adaptation potential; diversification potential; innovative development potential. Approaches to the inspiration of modern concepts of development in small and medium-sized businesses, including managed integration, catching up and advancing modernization and innovative development, have been formed; integrated inter-level digitalization; formation of a lean economy; formation of an eco-oriented «green» economy. Conclusions. The results of the study can serve as a basis for developing strategic plans for the development of small and medium-sized businesses and state regulation in the field of ensuring integrative security at different levels of the socio-economic system.
Impact of Dimensions, Apertures and Terminals on Stray Inductance of the Laminated Busbar
Authors: Venugopal Aravind , Robert Femi
Published: December 2022

This paper presents a systematic investigation of the impact of physical parameters such as dimensions, apertures and terminals, on the busbar inductance. A planar laminated busbar with copper conductors and a polyamide insulator is studied using a 3D FEM (Finite Element Modelling) based simulation software. The impact of dimensions such as conductor length, width and thickness, depth of insulator, the effects of aperture number, size, position and connection terminals on the busbar inductance are examined. The magnetic flux density, current density involved and its dependence on the self and mutual inductance of the laminated busbar is analyzed. Laminated busbars provided lower inductance with decreased conductor length, thickness, aperture diameter and depth of insulator. Also, the increased width of the busbar is of the essence for the design of a low inductance busbar. Low inductance laminated busbars are highly beneficial in power converters, powertrain inverters in electric vehicles, photovoltaic converters.
The Impact of Lockdown during COVID-19 Pandemic on Physical and Mental Health of Adolescents
Authors: Charatcharoenwitthaya Kantnatt , Niltwat Sorachat
Published: December 2022

The COVID-19 pandemic is a once-in-a-lifetime incident whose impact touched everyone from all walks of life. Such an unparalleled global event warranted unprecedented measures to mitigate the imminent public health catastrophe and protect risk groups. However, these actions have inevitably marginalized the physical and mental health of adolescents who were at a lower threat of adverse physical outcomes from COVID-19 infection. Restrictive public health measures resulted in disruption of routines from the closure of the school and public spaces, social isolation, loneliness, lack of engagement, and boredom. These impacts culminated in physical inactivity, sedentary lifestyle, eating disorders, and obesity and led to physical changes that have long-term implications. Equally, the substantial psychological stress of the pandemic resulted in an increased report of anxiety, depression, behavioral problems, and suicide attempts among adolescents in both previously healthy and those with pre-existing mental conditions. This narrative review provides a brief overview of the current evidence of the physical and mental impact of the pandemic lockdown on adolescent health and discussed interventional implications.