bluuebunny/crossref_metadata_2025 huggingface dataset:
Desenvolvimento de um Processo para Anodização com Utilização de Cátodo de Carbono em Parafusos Biomédicos
Authors: Listone Poliana , Pauli Guilherme , Ferreira Lucas , Lovatel Ana Júlia , Wolfart Jr. Mário
Published: May 2023

A partir da intensificação do processo de Globalização Tecnológica e o advento da chamada Indústria 4.0 e seus processos supereficientes, inúmeras áreas da indústria de transformação buscam o aperfeiçoamento técnico como única garantia de oferecer aos clientes produtos de qualidade competitiva ao nível global, além da obtenção de processos eficientes e de baixo custo, capazes de reduzir os custos finais e assim, apresentar preços competitivos, destacando-se nesse sentido a indústria médica e odontológica. O presente estudo parte da importância dos biomateriais para a indústria biomédica, especialmente o caso do titânio. Em parceria firmada com a empresa Protus Materiais para Medicina, foi idealizado um novo processo de anodização de alguns corpos de prova de titânio puro Grau 2, utilizando eletrólito de ácido sulfúrico para coloração dos corpos de prova. As cores obtidas podem ser utilizadas para fins de identificação de componentes fabricados com as liga de titânio, e esta tecnologia pode vir a ser implantadas em diversas empresas da área de biomateriais. Conclui-se, a respeito do novo processo, que foi possível obter a coloração dos corpos de prova exatamente como esperado, caracterizando-se uma inovação de processo.
A single-cell multi-omics map of cell-type-specific mechanistic drivers of multiple sclerosis lesions
Authors: Elkjaer Maria , Hartebrodt Anne , Oubounyt Mhaned , Weber Anna , Vitved Lars , Reynolds Richard , Thomassen Mads , Rottger Richard , Baumbach Jan , Illes Zsolt
Published: May 2023

Despite major progress in understanding the mechanisms in progressive multiple sclerosis (PMS), the underlying drivers of compartmentalized and sustained inflammation have not been resolved. To gain insights into the interplay between inter- and intra-cellular mechanisms and deconvolute the complex niche of lesion evolution, we have integrated single cell chromatin accessibility and transcriptome data for different white matter (WM) lesions from patients with PMS combined with spatial transcriptomics of chronic active lesion border. The PMS-specific oligodendrocyte genetic program was governed by the KLF/SP gene family involved in myelination and stress-induced iron uptake. The transferrin gene (TF) and its receptor LRP2 were highly expressed across all lesion types in oligodendrocytes suggesting autocrine communication of iron uptake and were co-localized at the outer border of the chronic active lesion. The genomic accessibility of the structural protein (VIM) and the cystine/glutamate antiporter (SLC7A11) was significantly reduced, and the genes were downregulated in oligodendrocytes. We identified oligodendrocytes expressing the osteopontin gene and complement at the outer edge of the chronic active lesion. We describe a metabolic astrocyte phenotype at the lesion border and an astrocytic-neuronal axis through FGF signaling (FGFR3-FGF13) inside the chronic active lesion. We also identified two distinct B cell co-expression networks with different location and gene expression preferring different lesion types. With single cell multi-omics, we were able to get a snapshot of specific cell types with distinctive molecular signatures and pathways, including their interactions and locations contributing to lesion fate.
Sensitivity Analysis of Counterweight Double-Row Pile Deformation to Weak Stratum Parameters
Authors: Wang Qiongyi , Zou Liang , Niu Yungang , Ma Fenghai , Lu Shasha , Zhang Cun
Published: May 2023

For deep excavation projects with weak strata such as filled stones and mud, not only is excavation difficult, but instability and deformation problems are also prone to occur. In order to explore the sensitivity of weak strata parameters to the deformation of counterweight double-row piles, this paper takes a deep foundation pit project in Shenzhen as the research background, uses the finite element analysis software MIDAS GTS NX to conduct numerical simulation analysis of the excavation process of the foundation pit project, and compares the numerical simulation analysis results with on-site measured data. Finally, orthogonal test method and theoretical analysis method are used to analyze the sensitivity of three weak strata parameters on the deformation of counterweight double-row piles. The results show that the cohesive force C is the key influencing factor, the internal friction angle φ is an important influencing factor, and the elastic modulus E is a general influencing factor. The research results have certain engineering guidance significance for the design and construction of deep foundation pit projects in weak strata.
The Impact of Overnight Work on Employee's Health and Lifestyle among Korean Adults: An Age-and Gender-Matched Study
Authors: Hwang In-Whi , Choe Ju-Pil , Hwang Soo-Ji , Shen Jun-Hao , Lee Jung-Min
Published: May 2023

Shift work has become more widespread globally as the demand for round-the-clock production and service industries continues to grow. This study investigated the health and lifestyle disparities between day and overnight workers, focusing on the impact of work schedules on employee health. We used the raw data from the 2018–2021 Korea National Health and Nutrition Examination Survey involving 604 adult workers. The results revealed that overnight workers faced increased risks for health concerns such as sleep deprivation (weekday sleep time: Day = 6.78 ± 1.35, Overnight = 6.36 ± 1.65, p < 0.00), type 2 diabetes (HbA1c (%): O.R = 5.66, 95% CI: 2.57–12.45) compared to day workers. Furthermore, sedentary behavior time (≥ 601 minutes: O.R = 2.12, 95% CI: 1.25–3.60) and lifestyle factors (white-collar workers: O.R = 0.49, 95% CI: 0.28–0.85, low-income individuals: O.R = 2.32, 95% CI: 1.28–4.19, smoking status: O.R = 2.75, 95% CI: 1.70–4.43) were found to be associated with the likelihood of working overnight. The study emphasizes the need for targeted interventions, policies, and collaboration to address overnight workers' unique challenges, support their well-being, and raise awareness of associated health risks.
Multi-view image-text emotion analysis network
Authors: Gao Weijun , Sun Zibo , Liu Shujun
Published: May 2023

A range of techniques to convey emotions through visuals and texts have emerged as a result of the rise of social media and the diversification of information delivery channels. The study of social media emotion based on texts and images has grown in popularity in recent years. Multimodal sentiment analysis approaches have advanced quickly since deep learning and some fusion algorithms first appeared. Existing multimodal models, however, have the issue of overlooking the lack of alignment between various modalities and the insufficient extraction of information for a single view of an image, which produces less-than-ideal results.In order to capture the correlation between objects and scenes in images and text, we introduces a cross-modal alignment module into the Multi-view Image Text Sentiment Analysis Network (MITN). Additionally, a stacked pooling module is used to combine multimodal data. On the MVSA-Single and MVSA-Multi datasets, experimental results demonstrate that the MITN suggested in this paper outperforms the baseline model.
Cognitive Activation as an Aspect of Literature Instruction
Authors: Nissen Anna
Published: May 2023

In this study, the concept cognitive activation is used to assess and discuss teaching quality in Swedish and Norwegian lower secondary literature instruction. Drawing on video data from 54 classrooms, it investigates the cognitive activation potential (CAP) of tasks and reading activities. It also investigates how and to what extent teachers, through their instructional support, increase or decrease the CAP of these tasks. The objective CAP of 280 tasks was estimated, ranging from low to high on a four-point scale. As tasks are not always carried out in the way teachers initially intended, the realised CAP of all the tasks was also estimated. In one third of all the sampled tasks, literary texts were read. During more active work with texts, the objective CAP was mostly of a medium-high level. However, students were seldom required to analyse, compare, and interpret literary texts. The realised CAP often remained unchanged by teachers’ instructional support. This suggests that there is room for teachers to improve and increase their interaction with students in ways that may enhance the latter’s literary competence. Implications for students’ learning and development of literary understanding are discussed.
Líquen plano bucal
Authors: Hanny Paula Rodrigues MARTINS  , Gabriele Apoluceno de SOUZA  , Elídio RODRIGUES NETO  , Roberta Francisca Martins CASTRO
Published: May 2023

Introdução: O líquen plano é uma desordem mucocutâneaimunologicamente mediada que afeta pele e/ou mucosa. Em geral, os estudosrevelam que a prevalência varia de 0,02 a 1,2% da população. Relato docaso e conclusão: Um caso clínico de líquen plano bucal diagnosticado etratado na Clínica Odontológica da Faculdade São Lucas será apresentado,assim como os resultados obtidos após tratamento com corticóide tópico.
Microwave-induced Reactions for Pyrrole Synthesis
Authors: Kamboj Monika , Bajpai Sangeeta , Banik Bimal Krishna
Published: May 2023

Heterocycles are organic compounds, the most important pharmaceutical skeleton
widely distributed in nature. Many of them possess medicinal as well as pharmacological activities.
Pyrroles are well-known five-member-privileged scaffolds with pharmaceutical potential.
Pyrrole is the component of complex macrocycles, including porphyrins of heme and
chlorophylls. Nowadays, the development of microwave-supported synthetic strategies for
such biologically relevant heterocycles is an important objective. Microwave-induced pyrrole
synthesis has become an environmentally benign route in organic transformation with reduced
reaction time and high yields. This mini-review focuses on the eco-friendly microwaveinduced
synthesis of pyrroles, their derivatives, and their potential pharmacological applications,
covering literature up to 2022.
Development of Tumor Markers for Breast Cancer Immunotherapy
Authors: Fang Qianqian , Shen Guoshuang , Xie Qiqi , Guan Yumei , Liu Xinlan , Ren Dengfeng , Zhao Fuxing , Liu Zhilin , Ma Fei , Zhao Jiuda
Published: May 2023

Although breast cancer treatment has been developed remarkably in recent
years, it remains the primary cause of death among women. Immune checkpoint
blockade therapy has significantly altered the way breast cancer is treated, although not
all patients benefit from the changes. At present, the most effective mechanism of
immune checkpoint blockade application in malignant tumors is not clear and efficacy
may be influenced by many factors, including host, tumor, and tumor microenvironment
dynamics. Therefore, there is a pressing need for tumor immunomarkers that can be
used to screen patients and help determine which of them would benefit from breast
cancer immunotherapy. At present, no single tumor marker can predict treatment
efficacy with sufficient accuracy. Multiple markers may be combined to more accurately
pinpoint patients who will respond favorably to immune checkpoint blockade medication.
In this review, we have examined the breast cancer treatments, developments in
research on the role of tumor markers in maximizing the clinical efficacy of immune
checkpoint inhibitors, prospects for the identification of novel therapeutic targets, and the
creation of individualized treatment plans. We also discuss how tumor markers can
provide guidance for clinical practice.
TENSION TYPE HEADACHE (TTH)
Authors: Muthmainnina Auliya Nur , Kurniawan Shahdevi Nandar
Published: May 2023

Tension Type Headache (TTH) is the most common type of headache in all age groups worldwide. Because of its high prevalence and possible association with medical and psychiatric comorbidities, TTH has a large socioeconomic impact. TTH is the type of headache that most patients suffer from, ranging from mild to severe pain that reduces their ability to carry out daily activities. TTH can be classified into an episodic tension-type headache (ETTH) and chronic tension-type headache (CTTH). The lifetime prevalence of TTH is high (78%). Approximately 24% to 37% experience TTH several times a month, 10% experience weekly and 2% to 3% of the population have chronic TTH disease. TTH treatment is carried out with pharmacological and non-pharmacological approaches
Door het oog van de naald: het Cappadocisch Grieks
Authors: Daveloose Eline
Published: May 2023

Cappadocian is an extremely endangered Greek dialect that was spoken in Central Turkey until the Greek-Turkish Population Exchange of 1923-1924. This involuntary emigration to Greece caused the near-extinction of this dialect. Nowadays the number of Cappadocian speakers and semi-speakers has decreased to approximately 2,800. Fortunately this very remarkable dialect, which was thoroughly influenced by the Turkish language, has been captured in many orally transmitted folktales that were recorded by philologists and dialectologists from the nineteenth century onwards. This paper presents a critical edition of a hitherto unpublished folktale: ‘The Shepherd’, a very short story in the Cappadocian subdialect of the village of Axo, recorded by Richard M. Dawkins. The edition is followed by a Dutch translation of ‘The Shepherd’ and a folkloristic discussion on its origin. This folktale is most likely one of the numerous versions of the story about the one-eyed giant, the Cyclops, best known from its variant in Homer’s Odyssey.
Laccase: A Green Solution for Environmental Problems
Authors: Sondhi Sonica , Chopra Navleen Kaur , Kumar Aditya , Gupta Naveen
Published: May 2023

A multicopper oxidase, laccases catalyze the four-electron reduction of the substrate with the use of molecular oxygen. Laccases are abundant in nature and can be found in virtually every form of life on the planet. Generally speaking, laccases are classified into three types: blue, white, and yellow. Plant, bacterial and fungal laccases all have the same trinuclear copper site for substrate reduction. Non-phenolic as well as phenolic molecules are both capable of being catalyzed by this enzyme. Laccases are used in a wide range of industries that make use of phenolic chemicals. Laccases have been the subject of recent research because of their unique features. Laccase, its sources, manufacture, purification, and applications in many sectors are discussed in length in this review.
Community-Led, Cross-Sector Partnership of Housing and Health Care to Promote Aging in Place (Unite Health Project): Protocol for a Prospective Observational Study
Authors: Skolarus Lesli , Thrash-Sall Erica , Hellem Abby Katherine , Giacalone Jr Michael , Burke James , Lin Chun Chieh , Bailey Sarah , Corches Casey , Dinh Mackenzie , Casetti Amanda , Mansour Maria , Bowie Kaitlyn , Roth Rylyn , Whitfield Candace , Sales Anne
Published: May 2023

Background

For many older Americans, aging in place is their preferred living arrangement. Minoritized and socioeconomically disadvantaged older adults are up to 3 times more likely to experience disability than other groups, which increases their likelihood of being unable to age in place. Bold ideas to facilitate aging in place, particularly among vulnerable populations, are needed. One such idea is the Unite care model, a community-initiated, academic-supported, cross-sector initiative that combines 2 sectors: housing and health care. The Unite care model colocates a federally qualified health center clinic on an older adult affordable housing campus in Flint, Michigan.

Objective

There are two aims to this study. Aim 1 is to evaluate the implementation of the Unite care model in terms of acceptability, adoption, and penetration. Aim 2 is to determine which older adults use the care model and whether the care model promotes aging in place through risk factor reduction and improvement in the physical and social environment.

Methods

We will assess the care model using a concurrent, exploratory mixed methods design. For aim 1, acceptability will be assessed through semistructured interviews with key stakeholder groups; adoption and penetration will be assessed using housing and health care records. For aim 2, residents residing in the Unite clinic building will participate in structured outcome assessments at 6 and 12 months. Risk factor reduction will be measured by change in systolic blood pressure from baseline to 12 months and change in the physical and social environment (item counts) will also be assessed from baseline to 12 months.

Results

Data collection for aim 1 began in July 2021 and is anticipated to end in April 2023. Data collection for aim 2 began in June 2021 and concluded in November 2022. Data analysis for aim 1 is anticipated to begin in the summer of 2023 and analysis for aim 2 will begin in the spring of 2023.

Conclusions

If successful, the Unite care model could serve as a new care model to promote aging in place among older adults living in poverty and older Black Americans. The results of this proposal will inform whether larger scale testing of this new model of care is warranted.

International Registered Report Identifier (IRRID)

DERR1-10.2196/47855
Determination of Economically Optimum Nitrogen Fertilizer for Bread Wheat in Shashemene District, West Arsi Zone of Oromia, Ethiopia
Authors: Kitila Kasahun , Chala Abay , Workina Mekonnen
Published: May 2023

The objective of this study was to determine the bread wheat’s ideal level for nitrogen fertilizer applications on Eutric andosol. The treatments included phosphorus (0, 10, 20, 30, 40kg/ha) and nitrogen (0, 46, 69, & 92kg/ha) at four levels each in a factorial combined effect of complete block design with three replications. a 3m x 3m plot with a 150kg/ha seed rate  was used. Wheat variety called “Ogolcho” was applied to evaluate the treatments. The results from the analysis of variance demonstrated that there were significant differences (p 0.05) between all of the applied treatments. The application of 46kg/ha N and 92kg/ha P2O5 together resulted in the highest grain yield (5358kg/ha), while the lowest grain yield was obtained. at the control treatment.. However, there are no significant differences (p<0.05) between the combined effects of Nitrogen and phosphorous fertilizers levels above 46kg/ha on grain yield response. This implies that the application of N and P2O5 greater than 46kg/ha may not be economically important. Therefore, 69 N kg ha-1 N fertilizers was determined as economically feasible optimum N rates at 2655%, MRR on Eutric andosol in Shashemene district for Bread wheat.
PHARMACOKINETIC STUDY IN HUMANS AND IN VITRO EVALUATION OF BIOENHANCED BILAYER SUBLINGUAL FILMS FOR THE MANAGEMENT OF ACUTE MIGRAINE
Authors: BHYAN BHUPINDER , BHATT DINESH CHANDRA , JANGRA SARITA
Published: May 2023

Objective: Long-lasting migraine pain is one of the most disabling neurological disorders and requires a quick onset of action from the administered dosage form. This study aimed to provide sublingual administration of the frequently used combination of NSAID and triptan in order to trigger their action immediately by escaping the first-pass metabolism, simultaneously improving patient compliance.
Methods: In the present research, sublingual bilayer films were developed by joining the two loaded layers with zolmitriptan and piroxicam, respectively. Each layer was prepared and loaded separately using the traditional solvent casting method. Mechanical support was provided by the 1:1 combination of HPMC E-15 and pullulan, which were used as water-soluble film-forming polymers with polyethylene glycol 400 as a plasticizer. Films were evaluated for various physicochemical and mechanical properties. Finally, a pharmacokinetic study was performed on six healthy human volunteers to compare the PK parameters of the best formulation, BSTF-3, with those of a commercially available formulation. Sepitrap 80 and Sepitrap 4000 were used as bio-enhancers to achieve faster systemic delivery.
Results: The thin, flexible bilayer films were observed to provide quick action alone with increase patient compliance by preventing the first-pass metabolism and dysphagia. Sepitrap 80 successfully increased the permeation of both drugs. Approximately 92 percent of zolmitriptan was released from the formed bilayer sublingual thin films within 3 min, whereas 92 percent of piroxicam was released within 4.5 min from the best formulation. Within 30 min of the commencement of the pharmacokinetic investigation, plasma concentrations of the active component began to rise rapidly.
Conclusion: When compared to commercial formulations, the developed films had a greater AUC and Cmax with a shorter Tmax, indicating a faster trigger of action and higher bioavailability.
FABRICATION AND DEVELOPMENT OF DISSOLVING MICRONEEDLE PATCH OF BUTORPHANOL TARTRATE
Authors: TIWARI AMAN , SHARMA SHUBHAM , SONI PRAKASH KUMAR , PASWAN SURESH KUMAR
Published: May 2023

Objective: Butorphanol is a commonly used medication for the management of postoperative pain and suffers low bioavailability and high first-pass metabolism. The objective of the current studies was to develop a butorphanol tartrate-loaded dissolving microneedle patch to overcome the limitation of first-pass metabolism without causing any discomfort to the patient.
Methods: Butorphanol tartrate-loaded microneedle patch was prepared using Lapox resin micro-molds. The microneedle patch was optimized using the box-Behnken design and the quantity of PVA, HPMC K4M, and HPMC K15M was optimized and evaluated for fractured axial force, microscopic evaluation, in vitro drug permeation studies, and ex-vivo permeation experiments.
Results: The developed microneedle patch meets all the evaluation parameters within the desired range. The height and tip diameter of the microneedles were found to be 700 µm to 800 µm and 60 µm to 61 µm. An axial fractured force of the optimized microneedle patch was found to be 189.67 N, suitable for penetrating the stratum corneum. The in vitro cumulative % drug permeated showed the permeation of the drug for 8 h with a total of 89.12 %, which shows the permeation of the drug occurred in a controlled manner.
Conclusion: Butorphanol tartrate-loaded microneedle patch was successfully developed and the results concluded that the microneedles were hard enough to pass the stratum corneum and release the drug into the systemic circulation without reaching the pain receptors; further, the release study suggested that the drug was released for a prolonged period eliminating the problem of first-pass effect and frequent administration.
The Crisis of Liberati in George Gissing’s New Grub Street
Authors: Haixia Du
Published: May 2023

George Gissing is a famous essayist and novelist in the late Victorian era. His masterpiece New Grub Street reveals the negative impact of literary marketization on literature and even culture by describing the different living conditions of literati. The novel depicts three different types of literati images, namely idealists who adhere to artistic standards, utilitarians who cater to the market, and female writers who are on the edge of literature, thus reflecting the writer's critical attitude towards the social reality that literature has become a commodity.
Estilos alfareros del Período Tardío en el Noroeste argentino
Authors: Bugliani María Fabiana , Fernández Sancha Sofía
Published: May 2023

This paper contributes to the characterization of late-period ceramic styles in northwestern Argentina by studying a ceramic assemblage recovered from the Loma l´Ántigo site, a residential settlement in the Cajón Valley (Catamarca, Argentina) between the late 13th and late 15th centuries. The research describes and analyzes visual aesthetics —morphology, surface treatments, and iconography— and uses low magnifications to characterize the ceramic material. Then, it compares the results with knowledge from neighboring regions to propose the existence of shared aesthetic and technological patterns that span several geographical areas and traverse the traditional style categories for the area and period.
Whatsapp Chat Exploratory Data Analysis
Authors: Singh Anurag Kumar , Bhatia Rishabh , Akki Dr. Praveena
Published: May 2023

Abstract: Whatsapp has been the most used mode of communication and has been an efficient one too. It consists of many conversations in groups and individuals. So, there might be some hidden facts in them. This project takes those chats and provide a deep analysis of that data. Being any topic, the chats are it provide the analysis in an efficient and accurate way. The main advantage of this project is that it has been built using libraries like pandas, seaborn, matplotlib, emoji etc. They are used to create data frames and plot graphs in an efficient way.
An Inter College Converse Platform to Deepen Student Collaboration
Authors: Rade Aarti , Bhosale Omkar , Swami Shivani , Jawalkar Omkar , Rajput Swati
Published: May 2023

Abstract: The Collaborative converse platform is developed to keep up college activities details like technical events, specialized webinars, placement support, workshops, project expo and courses and many more. It provides information on such events, keep up students’ participation and it keeps up branch details sports details, and furthermore gives the college accomplishments. In the current framework, all the information needs to be viewed in hard copy format. As a result, accessing specific data becomes challenging and time-consuming, leading to delays in decision-making. To address this issue, a web application can be used to simplify and secure the process, reducing the likelihood of errors. This would also enable efficient storage and retrieval of data through the system, thereby enhancing data security and reliability
Design & Model Making of Emergency Medicine Supply Drone
Authors: Goswami Satyam , Raj Rishi , Mallick Saikat
Published: May 2023

Abstract: Our study involves the implementation of a drone-based medicine delivery system utilizing the KK2.1.5 Flight Controller Board for Multirotor Drone. Our optimized drone is specifically designed to deliver medicine in rural areas, where transportation infrastructure may be lacking or geographical terrain may be difficult to traverse. Also, it can be used for contactless delivery of medicine in pandemic situation This innovative technology has the potential to be of great benefit in areas where traditional transportation services are inadequate or unavailable.
A Literature Review on Pneumatic Operated CPM Machine for Knee and Ankle
Authors: Mowade Dr. S. M. , Jambhale H. J. , Kapgate P. H. , Dhurve M. G. , Dharmik R. , Badge S. M.
Published: May 2023

bstract: Continuous passive motion (CPM) is a therapy in which a machine is used to move a joint without the patient having to exert any effort. A motorized device gently bends the joint back and forth to a set number of degrees, and the amount of movement and speed can be adjusted by the physical therapist. CPM machines are most commonly used on knee joints (after some types of knee surgery), but there are versions made for other joints as well. CPM is helpful when used according to a different principle than continuous motion. Rather than having the device flexing and extending the elbow on a continuous basis, I use the device asslow intermittent passive positioning. The day after release, my patients start slow intermittent passive placement, using the first 12 to 24 hours for rest and elevation. The machine is originally set to its most extreme acceptable extension and flexion positions. The antecubital fossa bandages must be taken off since they will prevent bending. The patient (or parent) is instructed on how to operate the machine-stopping button. The absolute minimum displacement rate is chosen. The patient is told to let the machine extend the elbow to its fullest extent, stop it, and hold it there for 20 to 30 minutes. When the button is pressed, motion is resumed up to the point of maximally tolerable flexion. Once more, the position is maintained for 20–30 minutes. The joint is kept in its most extreme position from the start of rehabilitation in this fashion, which is the intended outcome. There is no benefit to cycling the joint more frequently, and doing so could make the swelling worse. The indwelling catheter can be used to provide anaesthesia to treat pain and calm the muscular guarding if the CPM causes substantial guarding
Abusive Language Detection in Speech Dataset
Authors: Rathore Anurag , Kumar Anmol , Negi Aman , Chandra Nidhi
Published: May 2023

Abstract: In the topic, speech recognition there is a rapid increasing in it into area of engineering technology. Speech recognition delivers many different kinds of pros and it's been uses in a multiple field. Having a different type of language placed a restriction of talking between people. From this project we will going to create and develop to supports different systems that allows persons in that place or situation to change of data through interacting with end device users by voice or speech, after developing this project we will destroy the barriers of communication. This project takes that into consideration and makes an attempt to guarantee that it can identify speech and transform audio input into text. The speech is converted into text format. To overcome the offensive content in real-time every social media platform should implement an effectual hate speech detection system. There are many ways from that we can classify hate speech such as Machine Learning, Rule Based, Deep Learning Based and Hybrid
Coupxchange
Authors: Salian Ashika C , Shetty Bhuvan , V Gagan , Kumar Hithesh Udaya , N V Sunitha
Published: May 2023

Abstract: Coupons are a way for consumers to receive an incentive to purchase a product by using them. There have been a number of consumer concerns regarding coupon savings that have been exacerbated by the economic and financial crisis. With a strategic approach, online shopping applications can use coupons to attract and retain customers. Online social coupons that offer daily deals are becoming more popular. In addition to offering substantial discounts, these companies also allow their customers to experience a wide variety of products at a reduced cost, while at the same time being able to enjoy substantial discounts on those products. Mobile coupons can be time and/or location sensitive. However, it is not necessary that the customers use those coupons for themselves, since they are no longer useful for them, and it may go waste. So, in this proposed system we provide a facility for the customers to submit the coupons which are not useful to them and earn the points and get the required coupons by redeeming their points. In the backend coupon verification process will be done. This system recommends the coupon based on the category of sites they wanted. Recommendation logic is done in firebase functions. Recommended coupons will always be verified.
Neuropathy and Serum Vitamin B 12 Level in Metformin Treated Type2 Diabetic Patients of North India: A Single Centre Observational Study
Authors: Meena Dr. Khushbhu , Khan Saad , Soni Nishita , Bhamar Khushboo
Published: May 2023

Abstract: Aim: To determine the prevalence of neuropathy with the help of MNSI questionnaire (Michigan neuropathy screening instrument) Method: A single Centre observational study was completed in a tertiary care hospital between jan 2020 to april 2021. .In our study, 95 type 2 diabetes patients who had been taking metformin for a minimum of three months were included in a row. The severity of peripheral neuropathy (as measured by MNSI) and severe characteristics were compared. The length of diabetes, the length of metformin medication, dietary history, and HbA1c levels were some of these. B12 15 pg/ml was considered a definitive B12 deficit, while 220pg/ml was considered a potential B12 insufficiency. Result: In our research, we discovered a weak negative relationship (r=0.19) between the duration of metformin administration and vitamin B12 levels. In our investigation, the average vitamin B12 concentration was 99.22 pg/mL. Peripheral neuropathy and metformin medication duration had a favourable connection (r=1). The typical MNSI result was 11.2. Patients without peripheral neuropathy took metformin for an average of 3.5 years, whereas those with the condition took the drug for an average of 8.04 years.
Product Defect Identification System
Authors: . Rutu , M R Rakesh , L Pooja , C Hema
Published: May 2023

Abstract: Some uncontrollable defects will occur on the surface of metal work pieces during processing. The existence of surface defects not only affects the appearance of the finished product, but also affects the quality to a certain extent. Surface defect detection of metal work pieces can effectively improve product quality and production efficiency, and is an important link in the process of product quality control. This proposed system uses the convolutional neural network algorithm in deep learning to classify and detect metal surface defects. The surface defect recognition accuracy and defect detection rate of metal work is computed.
Computational Analysis of SARS-CoV-2 Genome Representing Intraspecific Variability
Authors: Kumari Uma , Malik Monu , Kumar Devendra
Published: May 2023

Abstract: The US National Institutes of Health, it is the successor to SARS-CoV-1, which was the virus that causedSARS outbreak in 2002-2004. SARS-CoV-2 is a virus of the species severe acute respiratory syndrome–related coronavirus (SARSCoV-2) Genomic analysis of 566SARS CoV2 virus populations to identify mutations as substitutions, deletions, insertions,and single nucleotide polymorphisms(SNPs).Clustal,ClustalOmega and MAFFT in order to align the Indian 566 SARS-CoV-2 sequences. SARS-CoV-2 is an enveloped virus consisting of a positive sense, single-stranded RNA genome of approximately 30 kb. There will be 3 possible reading frames in each direction of the RNA. So total 6 possible reading frame or (6 horizontal bars) would be there for every RNA sequence. +1, +2, +3 and -1, -2 and -3 ( in the reverse strand) are the 6 possible reading frames. The graphical abstract of the human coronavirus NL 63 genome of BLAST is represented by a red bar, which shows the most similar sequences. Bit score is anotherbiostatistical indicator used in addition to the e-value in a blast output and where comparing the sequence similarities search i.e. pairwise multiple sequence alignment shows a way of arranging protein or DNA sequence to identify region or similarity in clustal omega
Review on Analysis and Optimization of Gait Stroke Detection using Variable Sensors with Machine Learning Approach
Authors: Kalbende Neerja. P. , Asutkar Dr. G. M. , Bobate Dr. Ranjit
Published: May 2023

Abstract: Gait monitoring is considered an important marker of impairment, disability and gait symmetry. This research aims to develop a real-time consumer health monitoring system based on IoT sensors and machine learning technology to detect health disorders such as the onset of stroke. The proposed consumer stroke prediction system consists of IoT-based gait monitoring sensors, real-time vital signs monitoring, and a machine learning-based disease prediction model that predicts impaired and healthy gait. This study is useful for post-stroke walking coordination rehabilitation and consumer health monitoring service.
Advancement of Aerodynamics in Flutter Characteristics of AGARD 445.6 Wing
Authors: H Hanan , George Raiza Susan
Published: May 2023

Abstract: The aerospace sector has seen a significant prominence in the field of aerodynamics. Aerodynamic behaviour differs from one structure to the next depending on the specifics of each one. Due to flexible aeroplane structures, aeroelastic phenomena occur, when structural deformations alter aerodynamic forces. A feedback mechanism between the increased structural deformations and the added aerodynamic forces increases further aerodynamic loads. These interactions may diminish until they achieve an equilibrium state or, if resonance takes place, they may diverge drastically. The most challenging to forecast instability aeroelasticity aeroelastic phenomenon is flutter. An accurate finite element aerodynamic wing model is required for flutter study. A review of various approaches for conducting flutter analysis of AGARD 445.6 wing is presented in this paper. AGARD 445.6 wing has been used as standard configuration for the analogy of all aeroelastic behaviours. Under different flow regimes, the paper examines the platforms for finite element software that are used for flutter analysis.
Fabrication of Combined Savonius-Darrieus Wind Turbine
Authors: Negemiya A Arun , Nishanth M. , Raghuram PN , Saran M , Paul B L Victor
Published: May 2023

Abstract: A new wind turbine design has been developed by merging the lift-based Darrieus and drag-based Savonius designs. The Darrieus design is highly efficient but has uneven torque distribution, while the Savonius design has a self-starting mechanism but lower efficiency. The new design uses helically twisted Darrieus blades for even torque distribution and halfdrum Savonius blades for self-starting. The turbine was tested for various wind speeds and found to perform better than the individual designs. This increased efficiency allows for more power generation with the same amount of wind energy, and the elimination of the need for external motors reduces production and maintenance costs. This innovative design has the potential to revolutionize the wind turbine industry and provide a sustainable source of energy for the future.
Car Parking Automation and Premises Security System
Authors: Trimbake Sairaj
Published: May 2023

Abstract: India is a developing nation. With progress at such a rate, there are cars today at every corner, and parking these cars is a significant issue in the country. Car parking automation is important in today's world for several reasons. Effective use of space, With the growth of urban areas and the increase in the number of vehicles, efficient use of parking spaces has become essential. Also, the demand for personal vehicles is on its high. Automated car parking systems provide convenience to drivers by eliminating the need to search for a parking spot. Drivers can simply drop off their cars at the entrance and the system will take care of the rest. Overall, car parking automation is a must in today's world because it provides an efficient, convenient, and safe parking solution that can help improve the quality of life in urban areas while reducing the environmental impact of driving. To overcome this issue numerous parking systems are available. But the problem with these parking systems is they require more space and are expensive. So, our project is dedicated to developing a fully automatic parking system. The other major problem we are facing today is Inefficient Premises Security Systems. A poor Security System can lead to several problems. If your security system is ineffective, it may be easier for burglars or other criminals to enter your home or business and steal your valuables. This can result in significant financial loss and may also put you and your family or employees at risk. Our Premises Security System keeps your home and your surroundings safe, deters crime and is quite helpful in an emergency. We automated it to make it much more secure and safe which will help us in maintaining the safety of the residences.
Modelling and Analysis of Lithium-IoN Battery Pack
Authors: M Shivabharath Kumar , K Vishnu Bharathi , V Kavin
Published: May 2023

Abatract: As one of the most widely used energy storage technologies, lithium-ion batteries (LIB) play a significant role in modern society. The effectiveness of LIB is significantly impacted by thermal management. Phase change material (PCM)-based phase change cooling has emerged as a promising approach since it has a large latent heat and doesn't require additional pump power. In this study, phase change cooling with PCM has been used to numerically and experimentally analyse the thermal performance of a battery module containing 25 parallel 18650 lithium-ion batteries. First, in order to construct the heat generation model, the internal resistance of the unit cell has been experimentally tested. The impacts of PCM's thermophysical properties, such as thermal conductivity, are based on the heat generation model and the heat transmission model.
Android App Controlled Automobile Screw Jack for Light and Heavy Transport
Authors: Negemiya A Arun , AnandhaKrishnan B , Aswin N , Rosario A Johan , Kaviraj C
Published: May 2023

Abstract: This project is designed with Driver circuit with relay, BLUETOOTH APP (remote), Dc motor and jack model. Either the battery power or direct power supply is used to control the jack motor. The Bluetooth keypad is used to control the direction of the motor which is coupled with the spur gear. Relay is directly connected with the DC motor. When the start key is pressed the motor is operated in forward direction and the when the stop key is pressed the motor is stops automatically. The forward and reverse button in the remote is used to operate the motor is required directions. Bluetooth app Using To Control All Operation Using Wireless Communication.
Pet Monitoring System
Authors: Gite Anuradha , Wadile Hansika , Sargar Atul , Malishilwant Prathamesh , Shaikh Jareena
Published: May 2023

Abstract: The statement” Technology stems from humanity” accurately portrays the modern way of life. As humans increasingly interact with physical devices and those in the real world, it has become crucial to employ a natural and intuitive methodology. Living well has become a growing demand, and asa result, raising pets in an easy way has emerged as a major concern. To address this issue, this study examines how computation, communication, and control technologies can improve human interaction with pets through the Internet of Things (IoT) technology. The IoT offers a new method of operational efficiency,and our study focuses on improving the pet care system by incorporating this technology. Our research highlights the key improvements of the pet care system by utilizing the IoT and also addresses the needs of pet owners who are out for work without any trouble. To gain a morecomprehensive understanding of animal behavior, researchers can utilize GPS collars that record the location and behaviorof animals with high accuracy and frequency. By combining GPS collar data with remotely-sensed satellite images through wireless sensor networks (WSNs), researchers can gain insight into animal-landscape interactions and environmental impact.
Ataque cibernético al Hospital Ciudad Neily, Caja Costarricense Seguro Social, acciones realizadas, 31 de mayo-31 de agosto 2022
Authors: Leandro Ulloa Marcela
Published: May 2023

Objetivo. Describir el ciberataque y las acciones realizadas para mitigarlo, ocurrido en el periodo del 31 de mayo al 31 de agosto del 2022, en un hospital periférico 3 el Hospital Ciudad Neily (HCN) que pertenece a la Caja Costarricense Seguro Social, en la ciudad de Puntarenas, Costa Rica. Material y métodos. Es una investigación cualitativa observacional transversal en el periodo de tiempo del 31 de mayo al 31 de agosto del 2022. Resultados. En el HCN el 90% de los servidores sufrieron daños en su información; mientras que en la Caja Costarricense del Seguro Social (CCSS) sufrieron daños aproximadamente el 85% de los servidores existentes. En el HCN de las 315 terminales finales (computadoras, tabletas, otras) fueron infectadas 120 (38%); mientras en la CCSS de las 39650 terminales finales se infectaron 9600 (27%). Conclusión.  El ciberataque afectó los servidores y terminales finales que no tenían el software de Microclaudia, o que no lo tenían actualizado; además las que estaban encendidas en el momento del ataque o durante el mismo. Las acciones para atender la emergencia fueron determinación, valoración y repercusión de los daños el día del ciberataque; implementación de planes de contingencia para permitir la atención de los usuarios.  Durante los meses posteriores se realizó la determinación de insumos para continuar las atenciones en físico, limpieza de los equipos para poder subir los sistemas y subida de sistemas electrónicos.  Se deben de tomar medidas preventivas para futuros ciberataques que se determinaron con expertos en la materia.
La dirección de Trabajos Finales de Graduación en Administración en Servicios de Salud: ideas para reflexionar
Authors: Soto Calderón Ronald
Published: May 2023

Por medio de este artículo se presenta una aproximación a la comprensión del proceso de desarrollo de un trabajo final de graduación o tesis de la Carrera de Administración en Servicios de Salud, con el fin de que el lector tenga un acercamiento al proceso realizado por los estudiantes desde el encuentro con el tema desde un enfoque de investigación social hasta la redacción del informe final y su presentación ante el respectivo tribunal examinador. El objetivo del material es que las audiencias comprendan que el ejercicio de las personas que se forman en esta Carrera, abarca un amplio espectro de temas relacionados con el tema de Servicios en Salud, y desde un enfoque amplio, al abordar temáticas diversas sobre requerimientos múltiples de la población y desde la comprensión de la realidad por parte de la persona que desarrolla el TFG de una manera amplia, clara, solidaria y diversa. Así, quien desarrolla la experiencia de investigación busca elementos teóricos y metodológicos para acercarse a la realidad y brindar respuestas pertinentes a las realidades en estudio, para al final, entregar a la comunidad científica un producto riguroso y respuestas a realidades sociales concretas.
La promoción de la salud, como herramienta para abordar las grasas residuales del hogar
Authors: Chinchilla Barrantes Nora Patricia
Published: May 2023

Introducción: Del 2017 al 2018, el proyecto Manejo adecuado de las grasas residuales en beneficio de la salud pública, el ambiente y la estructura pluvial del cantón de Montes de Oca de la Universidad Estatal a Distancia (UNED), se vinculó con los EBAIS administrados por una universidad privada del Área de Salud de Montes de Oca, mediante actividades educativas sobre la manipulación y eliminación de las grasas residuales a nivel comunal. Objetivo: Compartir las estrategias de promoción de la salud brindando educación nutricional y ambiental sobre el manejo y eliminación de las grasas residuales en el hogar, implementadas en los EBAIS administrados por una universidad privada. Metodología: Se realizaron sesiones de trabajo con las autoridades y personal de los EBAIS, sobre las posibles herramientas a utilizar para la promoción de la salud, mediante la educación nutricional y ambiental en el manejo y eliminación de las grasas residuales en el hogar. Resultados: se utilizaron dos herramientas murales y charlas, con el personal en general, en sesiones sobre nutrición, actividad física y recolecta de aceite. Conclusión: La vinculación con los EBAIS administrados por una universidad privada del Área de Salud de Montes de Oca, permitió la promoción de la salud sobre las grasas residuales en los hogares, favoreciendo la difusión de buenas prácticas de manejo y eliminación responsable.
Splitting Mammalian Weeds: Monster for a Memory
Authors: Shana De Villiers
Published: May 2023

This is not a thesis of trying to mine a singular understanding, but a collecti(ion)(ve) body of research composed into a gesture. Other than my memories, I have only grazed the surface of the topics I will discuss (even then, memories are at the fragile grace of synaptic connections) There are holes here, tears that will take a lifetime to mend. As I will mention later, I am not interested in a singular whole. Holes, however, are curious places with a warm spot for happenings, so I am okay with the holes.

All patchworks are several and my obsession with their cobbled nature does not mean there are no moments of stillness and clarity. This work is an archive of the muddiness of being and I invite you to draw parallels with your own logic as you stumble through this patchy, leaky, weed forest.