bluuebunny/crossref_metadata_2025 huggingface dataset:
A67Advanced cardiothoracic Simulation -how to do it and who is it for?
Authors: Badran Abdul , Alzetani Aiman
Published: October 2023

There is a large backlog in surgery due to covid as well as surgical training [1]. We explored the feasibility of a dry lab simulation environment to teach advanced surgical specialty skills to learners with different levels of experience.

Session description: We ran 5 cardiothoracic surgical simulation courses over 2021-2022 with a total of 61 delegates. We covered coronary anastomosis, aortic valve replacement, video-assisted-thoracoscopic-surgery (VATS) lung wedge resection and pulmonary vessel dissection. Each skill station ran for 40 minutes including a 15-minute description and real-time demo.

Target audience: Participants included 36 medical students, 14 specialty doctors and 11 foundation doctors.

We used synthetic plastinated and resin printed models with modular metal frames to help with retraction and suspension of the area of interest for the cardiac models. For the VATS models a laptop with connected angled endoscopic camera was utilized. The lung models were 3D printed.

88% of all participants were able to complete all procedures successfully under supervision. 96% of all participants increased in confidence with the procedure following simulation compared to before. Interestingly only 44% of specialty trainees described themselves as confident in some procedures prior to simulation. Of the medical student cohort 95% had not had any previous simulation or surgical experience prior.

We have demonstrated the feasibility of a dry lab simulation programme for candidates of all experiences in cardiothoracic surgery. Confidence in surgical technique is low during the COVID era. Simulation improved confidence in surgical technique and must be offered more widely to enhance training experiences. No experience is necessary for successful simulation.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
A66Standardizing debriefing in Wales: the Triangular Approach
Authors: Diaz-Navarro Cristina , Jones Bridie , Stafford Jody , Mitra Suman , Catrin Cook Sara , Hawker Clare
Published: October 2023

Debriefing after simulation practice offers a crucial opportunity for guided reflection and learning. However, there are many structures and models available [1].

Health Education and Improvement Wales (HEIW) holds regular simulation webinars, workshops and conferences. During these events, the simulation community in Wales expressed their willingness to standardize debriefing in order to facilitate faculty sharing and to support interprofessional simulation.

National debriefing experts carried out a review of the relevant literature and devised the Triangular Approach to Debriefing, incorporating agreed debriefing principles, a simple structure and recommended strategies with links to relevant key articles.

This approach was shared and piloted by simulation faculty at a national workshop in September 2022. The feedback received was excellent. Comments received guided a document review. The final version was incorporated in the Essential Faculty Development Course and is currently in available in Welsh and English.

The triangular approach embraces a set of collaboratively identified principles, an easy to use structure and a summary of well referenced strategies:

Principles adopted include facilitating safe and constructive discussions, with Inclusion of all participants and respect for different learner needs, aiming to guide reflective practice and sharing of mental models with the highest level of facilitation possible.

A four-step structure (see

Recommended strategies cover psychological safety (such as ground rules, time management, authenticity and validation of contributions), how to focus the discussion, facilitation techniques, closing and meta-debriefing.

Debriefing structure in the Triangular Approach to debriefing

The Triangular Approach to debriefing has been welcomed by the simulation community in Wales. It is not expected to be the only way that facilitators debrief, but a gateway into good quality debriefing for new faculty, supporting the development of national expertise and encouraging to explore other available models as well as key debriefing literature.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
A58Mastery Based Simulation approach enabling social care teams to rapidly order small pieces of equipment to a person in their home
Authors: Mardon Julie , Brara Amrita , Beattie April , Wilson Lisa , McKinven Julie
Published: October 2023

Traditionally small pieces of equipment (e.g. Zimmer frame, commode, toilet frame and raise and walking sticks) required for frail older people in their home environment are ordered by Allied Health Professionals who are highly skilled in ensuring safety and functionality of the chosen item. However, the problem is that this process can sometimes take up to six months due to backlogs in the system. This means the person is living with unacceptable risk within their own home and losing the ability to perform activities of daily living (ADLs). This could also potentially result in falls and hospital admissions with the subsequent increase in morbidity and mortality.

The team working within social care are often the referrers into this service and we wondered if the use of simulation-based mastery learning which has been shown to allow safe successful dissemination of skills in other areas of health and social care could be used to enable home care teams to safely, timeously and appropriately order small pieces of equipment autonomously [1]?

Using the 7-stage approach to SBML, Checklists allowing the safe acquisition of small pieces of equipment aiding ADLs were developed by our trained mastery learning facilitators (senior AHPs). Sessions were delivered to a wide range home care team members. The training was delivered using mastery-based learning approach.

We believe that this is the only example of the use of SBML in the social care environment and are really excited about the safety benefits and the way SBML enables a person-centred approach to social care [2]. The SBML training and the train the trainers will be continued to be disseminated and we will continue to evaluate the impact both on practitioners, the time it takes to get a piece of equipment and also rates of falls and admissions to hospital.

The feedback from the sessions reflects the massive benefit perceived from the participants in the way their new ability will transform the way they can support people in their homes:

We can’t believe this is happening it will make such a difference to our practice and the care we can deliver to our clients in their own home

I never thought the day would come

We will continue to assess impact on home care teams especially whether this added enhanced role aids joy at work.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
A110Simulated Physiotherapy Placement: An alternative to clinical placement for first year undergraduate Physiotherapy students
Authors: Stevens Karen , Batty Helen , Mallett Ross
Published: October 2023

To address the existing workforce deficit within Physiotherapy an extra 500 Physiotherapists need to be trained every year - an additional 15% of current student numbers. The biggest barrier to expansion of student numbers is placement capacity. Novel and innovative models of placement are being trialled, with a strong emphasis on the four pillars of clinical practice. Simulation, and virtual based placements offer alternative models of placement provision [1]. Current literature has detailed successful simulated clinical placement within Physiotherapy using full or partial substitution of clinical placement. It has been shown that switching up to 25% of practice learning to a simulated model does not compromise student attainment or competency [2]. However, these studies tend to involve small student numbers. For simulated placements to be a practical alternative they need to be delivered at scale.

The aim of this pilot project was to develop, deliver and evaluate an on campus simulated placement experience for 140 first year Physiotherapy students at a large UK university.

A four-week program of activities was designed to simulate the core learning that occurs on a typical physiotherapy clinical placement. Including case scenarios with standardized patients, virtual case discussions with clinicians, expert patient panel, day in the life of videos, note writing workshops and live streaming of patient sessions. Students attended two observational days in practice with structured debriefing on campus. Themes for the placement included communication, risk assessment, patient journeys, wellness and effective learning on placement. The development of the learning activities was research and stakeholder informed. Clinical scenarios were co-designed with level 5 Physiotherapy students.

Placement evaluation was collected via a questionnaire including open ended questions and Likert scales (0-5). Students agreed that that placement was engaging and interesting (mean score of 3.45), with the greatest agreement that the placement had improved note writing, communication and understanding of professionalism. Students ranked simulated clinical scenarios and observation as their preference for activity, with peer learning to support these activities to be ranked the lowest.

A review of placement attainment data noted a correlation with previous clinical placement data. There was an increase in a student’s perception of their preparedness to go on a clinical placement pre and post simulated placement.

Large scale, simulated on campus placements are workable and a useful learning experience for first year Physiotherapy students.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
A106‘FY1 for a day’ an immersive programme to prepare final year medical students for foundation training
Authors: Appadurai Emily , Jones Kate , Hussain Faris , Cotter Melanie
Published: October 2023

Final year medical students are often anxious about commencing foundation training and feel underprepared for the practical responsibilities they are expected to conduct independently [1]. Consequently, a full day programme was created to facilitate immersive simulation of a typical working day of a Foundation Year 1 (FY1) doctor.

Aim: To provide an enriching programme empowering final year medical students to experience the practical aspects of foundation training (including areas of expressed difficulty), whilst creating a safe and realistic learning environment and providing opportunities for interprofessional learning and near-peer teaching.

Junior doctors from FY1s to Medical Registrars delivered the programme’s content. In the morning, three interprofessional simulation scenarios were delivered to the medical students and included nursing students for added realism. Each scenario reflected common ward-based and acute-setting situations that had minimal coverage in their undergraduate curricula. Afternoon stations were created to attenuate the medical students’ anxieties about the aspects of foundation training they perceived as difficult. Using a simulated ward, a mock handover was conducted. Students were then expected to complete the tasks of death verification, complex prescribing and female catheterization. The other stations simulated interpreting blood results, discussions with a microbiologist and requesting and discussing radiological imaging. During completion of all stations, the medical students carried and answered a bleep mimicking realistic distractions. Morning and afternoon debriefing occurred in small groups.

Following programme completion, all the medical students (

‘FY1 for a day’ is an effective and sustainable educational programme to potently prepare final year medical students for their foundation training whilst safeguarding psychological safety and fortifying multidisciplinary relationships.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
A88Designing a Multidisciplinary Chest Drain Course
Authors: Doherty Jane , Kasfiki Eirini , Wright Dave , Blackmore Andrew
Published: October 2023

In 2008 the National Patient Safety Agency reported 12 patient deaths directly related to chest drain insertion over a 3-year period. Since then there have been calls from publications highlighting the need for better education for clinicians [1]. Simulation has been shown to improve chest drain insertion technique [2], and multi-disciplinary simulation can encourage teamwork and communication skills [3]. Given that this procedure is an essential requirement for anaesthetic, intensive care, emergency medicine and internal medicine trainees, we decided to introduce a multi-disciplinary simulation course for the insertion of chest drains.

A basic needs analysis was carried out with stakeholders. Initially the course was designed to run for half a day, with a maximum of 12 candidates and a minimum of 3 faculty. A course timetable, course manual, equipment list and pre- and post-course feedback questionnaires were created. The course begins with a lecture, followed by three simulation-based workshops, which the candidates rotate between. These cover seldinger and surgical chest drain insertion, and the basics of chest ultrasound, using ultrasoundable chest drain manikins.

Feedback from the first course in July 2022 suggested that there should be a designated faculty team leader and healthy volunteers for the ultrasound workshop. We implemented this feedback and ran the course again in December 2022. Candidates were asked to rate their post course confidence at performing the procedure, with a score ranging between 1 and 7 (each number was assigned a qualitative value with 1 being unable to perform the procedure and 7 being extremely confident in performing the procedure). After the first course, the average score was 5 points. After the second, the average increased to 5.5. The course ran for a third time in April 2023, during which the duration of the workshops was increased and a lecture on aftercare was added. The average post course confidence score was 5.7. All candidates felt that the session fully met the learning objectives and would recommend the course to others.

After implementing changes to our course including assigning a faculty team leader, recruiting healthy volunteers, increasing the time spent in workshops and adding a session on aftercare, there has been an improvement in the candidates’ average post course confidence at performing chest drains and qualitative candidate feedback was positive. We would recommend our course structure to others designing a chest drain course.

Authors confirm that all relevant ethical standards for research conduct and dissemination have been met. The submitting author confirms that relevant ethical approval was granted, if applicable.
On-Farm Evaluation of Tractor Drawn Wheat Seed Drill
Authors: Kabaradin Abulasan
Published: October 2023

This experiment was conducted to evaluate the performance of a tractor-drawn wheat seed drill machine which can sow wheat and fertilizer at predetermined depths and row spacing. The machine performances were evaluated in terms of Seed and fertilizer rate, depth of seed placement, row spacing, plant population, field capacity, and field efficiency. Randomized complete block design with three forward speeds, three hopper loading, and three replications were used as experimental design. There were no visible or internal seeds damaged by the machine and it shows that there was no reduction in germination percentage when compared with the seed supplier recommendation. The seed and fertilizer rate was calibrated and recorded as 125 kg/ha and 150 kg/ha respectively for 20 cm row spacing. The seed drill was evaluated at speeds of 3, 4, 5 km/hr and hopper loading levels of H50, H75, and H100. Both the operating speed and hopper loading capacity of the machine had a significant effect on seed and fertilizer rate at p < 0.05. The average field capacity, field efficiency, and fuel consumption at 4km/hr speed of operation were 0.43 ha/hr, 85.93%, and 3.8 l/hr respectively. 378 to 380 plant populations per 1.2 m2 area were counted during seedling count. Depending on the results of the performance evaluation, it is concluded that the developed seed drill machine can be efficiently and economically used by the majority of farmers.
A Case study showing a Novel gene mutation in LAMB3 causing Junctional Epidermolysis Bullosa [Intermediate/Severe]
Authors: Bandla Shaile , Buraggada Dr , Peruchala Dr
Published: October 2023

ABSTRACT

Background: Junctional epidermolysis bullosa (JEB) is a type of Epidermolysis Bullosa, a group of genetic conditions that cause the skin to be very fragile and to blister easily. It is categorized into Herlitz type and Non-Herlitz types. JEB is inherited in an autosomal recessive pattern and the most common genetic mutations associated are LAMB3, COL17A1, or LAMC2, and LAMA3 genes.

Case presentation: This study reports a consanguineous couple, who are carriers for pathogenic variant for LAMB3 gene, with an affected child with a homozygous mutation in the LAMB3 gene causing Herlitz type of Junctional epidermolysis Bullosa/ Non-Herlitz type of junctional epidermolysis bullosa. Furthermore, prenatal diagnosis for the Gravida also showed the same pathogenic variant.

Conclusion: For autosomal recessive genetic conditions, it is advisable to perform a Trio whole-exome sequencing or next-generation sequencing to detect the genes associated with the disease. Depending on the type of variants involved prenatal diagnosis for the next pregnancy and treatment or management (if available) options can be offered/discussed.
Biochar: An Eco-friendly Approach for the Alleviation of Nitrate Leaching and Augmentation of Soil Health
Authors: Mirbakhsh Mandana , Rajabian Tayebeh
Published: October 2023

Our study investigated the efficacy of barberry biochar in reducing nitrate leaching in arid and semi-arid area. The experiment was conducted in factorial design investigating the effect of two biochar particle sizes (less than 1mm and more than 2.8 mm) and three biochar amounts (1%, 2%, and 3% by mass ratio) on nitrate leaching in soil. Our findings revealed significant reductions in nitrate leaching upon the application of barberry biochar. The experimental treatments had a significant effect on nitrate concentration in leached water in both sampling stages. Although the initial sampling indicated non-significant variances between particle size, clear statistical differences emerged in the second sampling. The smaller biochar particle sizes (less than 1 mm) recorded greater reductions by 76.3% in nitrate leaching compared to larger ones (exceeding 2.8 mm) that resulted in 66.2% reduction. Our results indicated that a 1% weight of biochar produced the lowest leaching rate, with reductions of 79.7% in the first sampling and 82.6% in the second sampling. Finer biochar particle sizes (< 1mm) were the most effective at reducing nitrate leaching, which achieved to an 80.9% reduction.
Overall, barberry biochar shows potential in mitigating nitrate pollution, enhancing soil quality, and promoting agricultural sustainability. It is important to consider the optimal biochar application rate and particle size to maximize its effectiveness in reducing nitrate leaching while minimizing any potential negative impacts on crop yield. Further research is required to optimize biochar application rates, particle sizes, and long-term effects in diverse agricultural systems. Implementing biochar as a soil amendment holds promise in improving soil health, water quality, and overall sustainability.
Transdermal patch: An effective transdermal drug delivery system
Authors: Yerra Jayasree , Pallerla Praneetha , Nimmagadda Srinivas
Published: October 2023

Transdermal drug delivery systems (TDDS) are topically administered medicaments. Transdermal drug delivery is defined as a self contained discrete dosage form, which when applied to the intact skin, will deliver the drug at a controlled rate to the systemic circulation. Transdermal patches are pharmaceutical preparation of varying sizes, containing, one or more active ingredient, intended to be applied to the unbroken skin in order to deliver the active ingredient to the systemic circulation after passing through the skin barriers. Compared to oral or systemic dosage systems, TDDS can offer a controlled release of the drugs through the skin into the patients, which could reduce the first-pass metabolism effects, lessen systemic side effects, improve the dosage efficacy by enabling steadier blood drug profiles throughout the treatment, and enhance patient compliance. Through a diffusion process, the drug enters the bloodstream directly though the skin. Since there is high concentration on the patch and low concentration in the blood, the drug will keep diffusing into the blood, the drug will keep diffusing into the blood for a long period of time, maintaining the constant concentration of drug in the blood flow. Characterization of transdermal patch is used to check it's quality, size, time of onset & duration, adhesive property, thickness, weight of patch, moisture content, uniformity & cutaneous toxicological studies. The present poster discusses the methods of preparation, characterization and applications of transdermal patches.
Penerapan Metode Jarimatika Untuk Meningkatkan Keaktifan Dan Hasil Belajar Matematika Kelas Ivsdn 2 Bunjeruk
Authors: Ardhi Shahibul , Fitria Apriani  , Nunik Amrita Aprilia
Published: October 2023

Penelitian ini berjudul “Penerapan metode jarimatika untuk meningkatkan keaktifan dan hasil belajar siswa pembelajaran Matematika kelas IV SDN 2 Bunjeruk. Penelitian ini bertujuan untuk mengetahui peningkatan keaktifan dan hasil belajar siswa dengan menggunakan metode jarimatika pada siswa pembelajaran Matematika kelas IV SDN 2 Bunjeruk. Metode penelitian yang digunakan adalah metode deskriptif dengan bentuk penelitiannya penelitian tindakan kelas. Hasil penelitian yang diperoleh adalah nilai rata-rata pada siklus I sebesar 66,4 dengan siswa yang mendapat nilai di atas 70 sebanyak 13 siswa dan pada siklus II sebesar 80,4 dengan siswa yang mendapat nilai di atas 70 sebanyak 16 siswa dan hasil analisis kegiatan siswa dan guru mengalami peningkatan dari siklus I ke siklus II dengan artian “adanya peningkatan yang positif dengan penerapan metode jarimatika terhadap kemampuan berhitung siswa kelas IV SDN 2 Bonjeruk Kecamatan Jonggat Kabupaten Lombok Tengah tahun pelajaran 2022/2023”. Dari data yang diperoleh, menunjukkan bahwa penerapan metode jarimatika dapat meningkatkan keaktifan dan hasil belajar siswa kelas IV SDN 2 Bonjeruk Kecamatan Jonggat.
ESTIMATIVA DE RECARGA DO AQUÍFERO ALTER DO CHÃO NA REGIÃO DO MUNICÍPIO DE ÓBIDOS-PA UTILIZANDO O MÉTODO WTF
Authors: Consentine Patrícia Jacaúna , Pedreno Gabriellen Yasmine de Oliveira , Moreira Joane Paola Papaleo Costa , Bruce Neta Iradene Brelaz , Lino Patrick Rogger de Melo , Azevedo Ramon Lima , De Melo Maria da Glória Gonçalves , Alves Neliane de Sousa
Published: October 2023

Diante das crescentes pressões sobre os recursos hídricos, conhecer as reservas de água subsuperficial tem se tornado fundamental no processo de planejamento e tomada de decisão quando se refere à gestão desses recursos. Estimar a quantificação da recarga das águas subterrâneas em ambientes freáticos é importante dentro desse processo. Neste sentido, este trabalho teve por objetivo estimar a recarga da água subterrânea em uma localidade do município de Óbidos, no Estado do Pará, abrangida pelo manancial hídrico subterrâneo Sistema Aquífero Alter do Chão (SAAC) empregando o método de flutuação do lençol freático (WTF). Utilizou-se dados da série histórica de janeiro a dezembro de 2020 do nível da água de um poço tubular monitorado pela RIMAS/CPRM, precipitação e evapotranspiração potencial, obtidos através de banco de dados disponibilizados pelo INMET. Tais dados foram processados no aplicativo Microsoft Excel ESPERE versão 2.44. Os resultados demonstraram uma recarga de 1536,79 mm, o que corresponde a 76 % do total de precipitação na região, que foi de 2023,8 mm. Portanto, destaca-se a importância das plataformas brasileiras de dados de monitoramento hidrogeológicos e a necessidade de atualização desses dados, tendo em vista sua contribuição para a gestão das águas subterrâneas.
Những Khó Khăn Hiện Nay Trong Việc Sống Lời Khấn Khó Nghèo Của Các Sinh Viên Tu Sĩ Tại Học Viện Thánh Anphongsô
Authors: Bùi Kim Cường , Nguyễn Du Đông , Nguyễn Văn Ngọc , Nguyễn Văn Hải , Nguyễn Hùng Vĩ
Published: October 2023

Mục đích của bài viết này là người tu sĩ cần có thái độ từ bỏ ý riêng mình, tránh ảnh hưởng từ gia đình và “hãy sống lại tinh thần đức khó nghèo, phải tránh mọi cái bên ngoài biểu lộ xa hoa cầu kỳ, nếp sống phải sao cho thanh đạm bình thường.”Hãy quay lại với Thầy Giêsu và bước theo Người, từ bỏ ý riêng như chính Đức Giêsu đã tự do chọn sống khó nghèo để làm theo ý của Chúa Cha. Người trở nên nghèo khó để sống cho Nước Trời. Vì thế, việc từ bỏ các an toàn vật chất, từ bỏ ý riêng chỉ có ý nghĩa nếu nó đến từ việc khám phá nước trời trong tương quan với Thiên Chúa. Việc liên đới với người nghèo có thể sẽ trở thành một con đường hữu hiệu nhất để phục hồi đức khó nghèo.
Abstract
The purpose of this study is that a monk needs to have an attitude of giving up his own will, avoiding the influence of his family and "reliving the spirit of poverty, must avoid everything outside that shows luxury and sophistication, and lead a normal life of frugality." Turn to Jesus and follow him, giving up your own will as Jesus himself freely chose to live in poverty to do the will of the Father. He became poor to live for the Kingdom of God. Therefore, the renunciation of material security, the renunciation of one's own will only makes sense if it comes from discovering the kingdom of heaven in relation to God. Solidarity with the poor can become the most effective way to restore poverty.
OPTIMIZATION OF WINTER WHEAT NUTRITION WITH ZERO TILLAGE TECHNOLOGY IN THE RAINFED ZONES OF SOUTHERN KAZAKHSTAN
Authors: TURGANBAYEV NO , SYDIK DA , KENENBAYEV SB , SYDYKOV MA , KAZYBAYEVA AT
Published: October 2023

The promising research showcased the results of herbicides’ uses, considering the quantitative composition of weeds with zero tillage technology of winter wheat cultivation. It revealed that when treating wheat seeds with the growth stimulator Vimpel (0.5 l/t) and micro-fertilization with Oracle (1.0 l/t) simultaneously etching with the fungicide Bunker (0.4 l/t), as well as, early spring treatment of crops in the tillering phase of winter wheat with the same stimulator (Vimpel, 0.5 l/ha) and micro-fertilization (Oracle multicomplex, 2.0 l/ha) simultaneous with the herbicide “Ballerina” (0.5 l/ha) application, the number of preserved plants before harvesting was 286.1 pcs./m2, reaching a height of 88.9 cm, with a productive bushiness of 1.15 pcs., grains per spike (22.2), 1000-grain weight (34.8 g), and collected dry grains at a standard humidity (22.1 c/ha). It was also evident that the competitive productivity of winter wheat also emerged when treating wheat seeds with biological fertilizer Biobars–M (1.0 l/t), the crop at the tillering stage with Biobars–M (0.5 l/ha), and the earring phase (0.7 l/ha). Similarly, using growth stimulants Vimpel and micronutrient Oracle multicomplex enhanced the grain yield with reduced cost of production (USD 61.3–66.0/kg) compared with the control version (USD 78.6 /kg). On one hectare of winter wheat crop, the net income ranged from USD 289.55 to 443.56.
Consideraciones sobre la aplicación del cupo de reserva del dos por cien de plazas para personas con discapacidad en las empresas públicas.
Authors: Rodríguez Escanciano Susana
Published: October 2023

Teniendo en cuenta que según el art. 42 de la Ley General de Derechos de las Personas con discapacidad, las empresas públicas y privadas que empleen a un número de 50 o más trabajadores vendrán obligadas a que de entre ellos, al menos, el 2 por 100 sean trabajadores con discapacidad, procede entender que el ámbito de aplicación de tal previsión se extiende a la Corporación RTVE.

Considering that according to art. 42 of the General Law on the Rights of Persons with Disabilities, public and private companies employing a number of 50 or more workers shall be obliged to ensure that at least 2% of them are workers with disabilities, it is to be understood that the area of application of this provision includes the Corporación RTVE.
¿En qué casos el pluriempleo es causa de despido disciplinario?, ¿y qué valor probatorio tiene el informe de un detective privado en el proceso de despido?
Authors: Areta Martinez María
Published: October 2023

La STSJ de La Rioja-SOC núm. 91/2023, de 26 de julio, confirma la procedencia del despido disciplinario de una trabajadora que, estando contratada por cuenta ajena como esteticista, desarrolla igual actividad profesional durante cuatro días consecutivos en otra empresa del mismo sector sita en localidad próxima y sin ponerlo en conocimiento de la primera para la que trabaja. La Sala fundamenta el fallo en el artículo 58.1 del ET, puesto en relación con el artículo 35.4 del Convenio Colectivo estatal para el sector de peluquerías, institutos de belleza y gimnasios, que tipifica como falta disciplinaria muy grave "El trabajo por cuenta propia o para otra empresa del ámbito funcional del convenio, sin autorización escrita de aquella a que pertenece". La empresa acredita los hechos imputados en la carta de despido por medio del informe de un detective privado, ratificado posteriormente por su autor en el acto del juicio oral. El caso ahora examinado invita a reflexionar sobre los siguientes aspectos: 1) el pluriempleo como causa de despido disciplinario, 2) la facultad del convenio colectivo para regular el pluriempleo y 3) el valor probatorio del informe de un detective privado y de sus anexos en el proceso de despido.

En Espagne, la convention collective nationale de la coiffure et des professions connexes ne prévoit pas l'obligation pour le salarié de prévenir son employeur d'un cumul d'emplois, c'est à dire, la convention collective ne contient pas une disposition prévoyant que le salarié qui souhaite occuper un second emploi dans le même secteur d'activité doit en informer obligatoirement son employeur et obtenir son autorisation. Cependant l'article 35, paragraph 4 de la convention collective prévoit que la violation de cette obligation est constitutive d'une faute lourde pouvant justifier le licenciement. La chambre sociale du Tribunal Supérieur de Justice de La Rioja a qualifié le licenciement comme approprié dans un arrêt du 23 juillet 2023 (nº 91/2023).
Species Identification of Potential Probiotic Lactic Acid Bacteria Isolated from Malaysian Fermented Food Based on 16S Ribosomal RNA (16S rRNA) and Internal Transcribed Spacer (ITS) Sequences
Authors: Ilyanie Yaacob , Huda Faujan Nur , Ida Muryany Md Yasin
Published: October 2023

Taxonomic identification of potential probiotic lactic acid bacteria (LAB) in fermented foods is essential as the microorganisms’ benefits are varied and often strain-specific. Using biochemical and physiological methods alone is inadequate to precisely distinguish each strain. In this study, molecular techniques were employed in the identification of 17 LAB isolated from three Malaysian fermented foods: belacan (BE), bosou (BO), and budu (BUM). The respective sizes of polymerase chain reaction (PCR) products from the isolates were approximately 1500 bp and 750 bp when amplified with the 16S ribosomal RNA (16S rRNA) and internal transcribed spacer (ITS) gene primers. The phylogenetic analysis using both gene sequences revealed that all BE and BO isolates were identified as Lactiplantibacillus plantarum, while all BUM isolates were identified as Lacticaseibacillus paracasei. Both 16S rRNA and ITS genes could disclose the identity of the isolates up to the species level. In summary, the use of the ITS gene in conjunction with the 16S rRNA gene can help with the more effective identification of potential probiotic LAB strains isolated from fermented food.
Effect of Temperature and Fermentation Time on Protease Production Using Decapterus macarellus Fish Waste
Authors: Mohd Alias Noralia , Kee Chua Gek , Ne Chew Few , Yazid Noraziyah Abu , Samah Rozaimi Abu , Mortan Siti Hatijah
Published: October 2023

The fish processing industries generate huge amounts of by-products which cause serious environmental and health problems. The environmental problems related to waste disposal can be reduced as the low cost of fish by-products contains nutrients that can enhance microbial growth and are useful for enzyme production. This research aims to investigate the effect of temperature and fermentation time on protease production from fish waste hydrolysate by using the Bacillus strain (Bacillus cereus). The pre-treatment and fish waste hydrolysate were carried out and continued with the production of protease. The effect of fermentation time was studied every 4 h for 72 h while the effect of temperature was investigated at temperatures ranging from 30 °C to 60 °C. The results showed the maximum protease production of 45.63 U/mL at 48 h of fermentation time and 44.908 ± 6.14 U/mL at a temperature of 50 °C. The current study provides insight into the effects of cultivation conditions on protease production from local fish waste industries for further optimization study to enhance protease production.
Development of Low Glycemic Index Cookies Made From Functional Cassava Pulp Flour
Authors: Hidayat Beni , Hasanudin Udin , Nurdjanah Siti , Yuliana Neti , Zukryandry
Published: October 2023

One of the food ingredients with the potential to be used as raw material for low glycemic index food is functional cassava pulp flour (FCPF) which has a dietary fiber content of 23.84% and resistant starch of 7.31%. The present research aimed to obtain the optimal substitution concentration of FCPF to produce cookies with the best nutritional, organoleptic, and physical characteristics and a low glycemic index. It was arranged in a Completely Randomized Design (CRD) with six levels of substitution concentration of FCPF, namely, 0% (control), 10%, 20%, 30%, 40%, and 50%. The results showed that the higher the concentration of FCPF substitution, the higher the fiber content, the resistant starch content, and the texture of cookies. Cookies with a 50% FCPF substitute concentration have the same organoleptic quality as those made from wheat flour (6.6 versus 6.9) but with the lowest glycemic index (40.29%). Cookie products with a 50% FCPF formulation are categorized as foods with a low glycemic index.
What is an isogloss?
Authors: Kabatek Johannes
Published: October 2023

This short contribution discusses the term and concept of isogloss: the space where a linguistic phenomenon exists or, by metonymic extension, the line that separates a particular linguistic phenomenon from another. Although the concept is currently used as an established and canonical term in linguistics, it is reasonable to explore its scope and the real sense that it carries, as well as to consider its origins and potential ambiguity in use. The main issue with the concept is that it seems to be theoretically necessary yet at the same time is not empirically attestable, which runs contrary to essential epistemological principles. We will seek to show that a) there is no contradiction between the existence of isoglosses as discrete units and the continuity of phenomena on the empirical level, b) the supposed end of the era of the diatopic anchorage of language in times of modern migration is a myth, c) that isoglosses should not be considered as established lines but rather as projections resulting from processes of individual constructions of spaces, and finally, d) that a central task of dialectology and of historical linguistics consists of the identification of the multi-layered superposition of different isoglosses that reflects the complex history of a language or variety.
Distancias reales y ficticias en los espacios lingüísticos
Authors: Moreno Fernández Francisco
Published: October 2023

This paper offers a general reflection on the concepts of “space” and “distance” in linguistics. It also presents an overview of the methods applied in the measurement of distances, among which those based on quantitative techniques from real data. The objective description of distances, however, presents such limitations that subjective factors, based on perception processes, must be considered. In this regard, the “focal model” for the analysis of linguistic perception is presented and the concepts of “conceived variety”, “perceived variety” and “imagined variety” are introduced. The analysis of linguistic distances is of interest not only for linguistics, but also for the analysis of social, economic, and educational processes.
Multilingüismo y turismo: visiones desde la península de Yucatán y Mallorca
Authors: Uth Melanie , Vanrell Bosch María del Mar
Published: October 2023

El turismo es un fenómeno territorial de contacto lingüístico-cultural que tiene impactos importantes tanto en las sociedades receptoras como, aunque en menor medida, en las sociedades de origen de los turistas. Aparte de las repercusiones territoriales y medioambientales, la práctica turística deja su huella en la cultura, la socio-demografía y la identidad de los destinos turísticos. Esta contribución aborda la relación entre el turismo y el multilingüismo, comparando el litoral del estado de Quintana Roo, en la península de Yucatán, México, con la isla de Mallorca.

El objetivo principal de nuestro trabajo es identificar tanto los puntos en común como las diferencias entre las dos regiones en el marco de los aspectos sociolingüísticos mencionados anteriormente, con el fin de distinguir las dinámicas lingüísticas regionales relacionadas con el turismo, por un lado, de aquellas dinámicas que operan a nivel global o transatlántico, por el otro. De esta manera, esperamos contribuir a un entendimiento más profundo de las dinámicas sociolingüísticas características para cada uno de los dos contextos.
Exploring the Coupling Relationship Between Dynamic Marketing Capability, Strategic Information Management, and International Startup Performance
Authors: Guo Fanghua , Husin Hartini binti
Published: October 2023

The ever-changing environment in a highly competitive marketplace presents unlimited business opportunities and endless challenges for international startups. To explore the coupled relationship between dynamic marketing capabilities, strategic information management, and international startup performance. For the first time, this study adopts a dynamic analysis and survey methodology and establishes a scoring and analysis model under a dynamic system. A questionnaire study with real data was conducted through 500 international startups in Hebei, China, and the data were processed and analyzed with the help of analytical software. The study discusses the coupling relationship between dynamic marketing capability, strategic information management capability, and enterprise performance, and reveals the intrinsic influence law of the three from multiple dimensions. Specifically, the three dimensions of dynamic marketing capabilities, namely, market knowledge management capabilities, interface synergy capabilities, and customer relationship management capabilities, can all positively affect the performance of enterprises, only the overall effect of the three dimensions on the performance is different, in which the market knowledge management capabilities can significantly improve the performance of enterprises. The strategic information management innovation of internationalized startups has a mediating effect between dynamic marketing capabilities and corporate performance, playing an indirect positive feedback role. The above study contributes to the future marketing management and performance improvement of internationalized startups.
THE CORRELATION BETWEEN STUDENTS’ SPEAKING ANXIETY AND SPEAKING ABILITY AT SMA NEGERI 4 BAUBAU
Authors: Nety Nety , Purnomo Bagas
Published: October 2023

The problem statement of this research was whether there was a significant correlation between students’ speaking anxiety and speaking ability at SMA Negeri 4 Baubau. This research aimed to determine whether there was a significant correlation between students’ speaking anxiety and speaking ability at SMA Negeri 4 Baubau. The method of this thesis was an ex post facto method. The population of this research was the grade eleven students at SMA Negeri 4 Baubau in the school year of 2022/2023 which consisted of a total population was 287 students. The technique of sample used in this research was simple random sampling and the sample of the research was 50 samples. The research was carried out by using a questionnaire and a test as the instruments. The questionnaire was used to find out the category of students’ speaking anxiety and the test was used to find out the category of students’ speaking ability. The data obtained using the questionnaire and test then were analyzed by descriptive statistical analysis, prerequisite analysis, and inferential statistical analysis. Based on the result of this research, it concluded that the Sig. value was 0.001. Because of the Sig. value was higher than 0.05, which meant that Ha was accepted and H0 was rejected. It meant that there was any significant correlation between students’ speaking anxiety and speaking ability on grade eleven students at SMA Negeri 4 Baubau.
Islas Cíes: una trampa eólica en la Ría de Vigo (Galicia, España) al final del último glaciar
Authors: Arce Chamorro Carlos , Vidal Romaní Juan Ramón , Sanjurjo Sánchez Jorge
Published: October 2023

Las Islas Cíes han constituido un obstáculo para los intensos vientos costeros del Atlántico Norte, especialmente durante las fases glaciares del Cuaternario. Al final del último glaciar el mar descendió más de 100 m por debajo de su nivel actual. Este descenso transformó el archipiélago en un relieve emergido de 300 m de alto, capaz de deflectar el viento y atraer, al mismo tiempo, sedimentos eólicos procedentes de una franja de plataforma continental también emergida. Bajo esta hipótesis, estos materiales eólicos se depositaron cubriendo el contorno de Cíes. Un ejemplo de estos episodios de acreción eólica es el afloramiento de eolianitas situado en la Isla de Monteagudo (Islas Cíes, Galicia, España), interpretado como una duna rampante que estuvo activa desde el final del Pleistoceno Superior, cubriendo parcialmente la vertiente oriental. Con un espesor de más de 3 metros y una edad (OSL) de 35 ka (b2k) en el muro y de 17 ka en el techo de la formación, este depósito es una prueba de la eolización desarrollada en la costa de Galicia durante miles de años, interrumpida al cesar los aportes durante el postglaciar holoceno.
Posibles evidencias morfo-sedimentarias del tsunami de Atacama de 1922 en el Parque Nacional Pan de Azúcar (norte de Chile)
Authors: Abad Manuel , Izquierdo Tatiana , Carrasco Germán , Rodríguez-Vidal Joaquín , Ruiz Francisco
Published: October 2023

El gran terremoto de 1922 de Atacama es uno de los mayores eventos sísmicos del siglo XX en el límite de subducción entre las placas de Nazca y Sudamérica. Los principales daños provocados por el tsunami asociado ocurrieron en el litoral del norte de Chile. En la ciudad de Chañaral, una de la más afectadas, se alcanzó una cota máxima de inundación de 9 m sobre el nivel del mar y una inundación horizontal de 200 m. En este trabajo se aborda el estudio del registro geológico de este evento en el Parque Nacional Pan de Azúcar, 10 km al norte de esta ciudad portuaria, donde se describen formas erosivas y campos de bloques a cotas topográficas por encima de la zona de acción de temporales de invierno. Este trabajo resalta la necesidad de profundizar en el análisis de depósitos de grano grueso en sistemas costeros áridos para la identificación del registro de tsunamis, donde su potencial de preservación es bajo y sus evidencias tienden a aparecer enmascaradas en el paisaje litoral.
Identification of potential CDK 8 inhibitor from pyrimidine derivatives via In-Silico approach
Authors: Baburao Patil Pramod , Trimbakrao Kumbhar Subhash
Published: October 2023

Pyrimidinesare six-membered heterocyclic scaffold present naturally in nucleic acid components and are promising leads for the synthesis of medicinally important compounds. Cyclin-dependent kinases (CDKs) with a serine/threonine catalytic core are important druggable targets for cancer therapy and the binding of regulatory subunits controls them. In the present study series of virtually designed pyrimidine derivatives were screened using molecular docking techniques against the cyclin-dependent kinase-8 (CDK8) as a targeted protein. The density functional theory calculation of compounds having good binding affinity was done to estimate the orbital energy. The molecular dynamics simulation of the best-docked compound with the CDK8 was simulated to estimate the effect of mobility on the interactions.Themolecular docking provided insights regarding the binding ability of the designed compounds with the targeted CSK8 structure. As a result, the docked compounds exerted good interactions with the CDK8, and the compound PB129 showed the highest negative binding affinity of -12.4 kcal/mol with the formation of two hydrogen bonds. The results of the simulation study indicated that the complex of CDK-8 and PB129 hasa tight binding with constant hydrogen contacts. Moreover, the density functional theory indicated that PB129 has strong orbital energy and this compound will show tight interactions by either donating or accepting the electron with protein structure. Studied compounds showed good results for the docking study by exerting tight binding with the CDK-8 (PDB 6T41). Compound PB129 showed stable confirmation over the simulation run and has good orbital energies. Compound PB129 may act as a lead against the CDK8.
Synthesis and pharmacological characterization of new curcumin ester pro-drugs with enhanced anti-inflammatory, anti-ulcerogenic and improved tissue distribution
Authors: Agrawal Nidhi , Jaiswal Meenakshi
Published: October 2023

In this work, curcumin- Non steroidal anti-inflammatory drugs (NSAIDs) conjugates were synthesized by esterification of the phenolic group of curcumin with the acid group of NSAIDs using the Steglich esterification method to enhance the anti-inflammatory activity of curcumin and to reduce the gastrointestinal side effects of NSAIDs. A set of bis C-NSAIDs conjugates was prepared by direct coupling of curcumin with Aceclofenac and Diflunisal respectively in good yield and characterized by Fourier-transform infrared spectra (FTIR) and Proton Nuclear Magnetic Resonance Spectra (1HNMR). In vivo, studies were performed to evaluate the toxicity, anti-inflammatory activity, bio-distribution, and anti-ulcerogenic studies of selected conjugates using different animal models. In Vivo, studies reveal enhanced biological activity with better tissue distribution of conjugates than that of parent curcumin and it could be a curcumin-based therapeutic molecule that might be explored further for its efficacy in managing inflammatory diseases.