bluuebunny/crossref_metadata_2025 huggingface dataset:
High-load beam for bridge span structures
Authors: Popov Igor P.
Published: December 2024

Aim. This work aims to increase the load-bearing capacity of tubular beams, allowing for a wider range of construction products.
Materials and Methods. The study utilizes geometric optimization methods and hypothetical experiments.
Results. A tubular beam with a liquid filler (hydraulic beam) is a round pipe, plugged at both ends, completely (without air pockets) filled with liquid. When the hydraulic beam is subjected to load, its side surface tends to deform. However, since the liquid inside is incompressible, it resists any reduction in volume. This resistance prevents the pipe from deforming under stress.
Conclusion. The load-bearing capacity of a hydraulic beam is five times higher than that of an I-beam and ten times higher than that of a tubular beam.
Unmanned aerial vehicle for monitoring the AC contact network
Authors: Kim Konstantin K. , Koroleva Elena B. , Rybin Peter K. , Stepanskaya Olga A.
Published: December 2024

Aim. To demonstrate the feasibility of using a contactless battery recharging method for an unmanned aerial vehicle during the monitoring of the AC contact network in railway transport.
Materials and methods. A mathematical model was created using the COMSOL Multiphysics 6.0 program. Maxwell's equations and the finite element method were applied to calculate the induced electromotive force across the on-board winding of an aircraft.
Results. We determined the optimal operating modes of the developed aircraft. The economic feasibility of its use for monitoring the contact network of railway transport is shown.
Practical significance. We developed an unmanned aerial vehicle with extended nonstop flight duration and an increased capacity for continuous monitoring.
Application of wavelet transform for recognition of acoustic signals of various defects of power transformers
Authors: Kuznetsov Andrey A. , Ponomarev Anton V. , Gorlov Anton V. , Volchanina Maria A.
Published: December 2024

Background: This study discusses the use of wavelet transform for processing acoustic signals when diagnosing power transformers. A simulator with various defects was used to explore the application of continuous wavelet transform. The study also outlines an algorithm for obtaining signal standards to identify different types of defects.
Aim. To develop a mathematical model for constructing reference acoustic control signals when processing data from a simulator with various defects. These signals will be used to identify and diagnose defects in real power transformers during their operation.
Methods. The study introduces expressions for signal transformation, presents acoustic control signals, and explains the formation of reference signals. It also describes the process of recognizing the closest signals in form, corresponding to different types of defects.
Results. The key results include expressions for signal transformation, acoustic control signals, and the formation of reference signals. The closest matching signals were identified, enabling accurate recognition of different defect types.
Conclusion. The research proposes a method for processing acoustic control signals, allowing the reproduction of various insulation defects of power transformers and the recognition of such defects according to the proposed parameters of the wavelet transform.
Opioid Kullanım Bozukluğu ve Farmakolojik Tedavisinde Kullanılan İlaçlar
Authors: Ertuğ Peyman , Ecemiş Serkan
Published: December 2024

Opioid kullanım bozukluğu dünyada önemli bir şekilde morbidite ve mortalite kaynağı olmaya devam etmektedir. Farmakoterapi, opioid yoksunluk semptomlarını hafifletmek, nüksetmeyi azaltmak ve uzun vadeli iyileşmeyi sağlamak amacıyla opioid kullanım bozukluğunun tedavisinde önemli rol oynamaktadır. Metadon, buprenorfin, nalokson, naltrekson, klonidin ile yapılan tedavilerin, opioid kullanım bozukluğunu düzeltmede, bağımlılığın tedavisinde ve aşırı dozdan ölümleri azaltmada etkili olduğu gösterilmiştir. Bu derlemede, opioid bağımlılığının biyolojik mekanizmaları, opioid kullanım bozukluğunun tedavisinde kullanılan farmakolojik ajanların farmakokinetiği, farmakodinamiği, endikasyonları ve yan etkileri hakkında bilgi verilmektedir.
Enerji İçeceklerinin Adolesanlar Arasındaki Tüketimi ve Sağlık Üzerindeki Etkileri
Authors: Turan Berra , Ocaktan Mine Esin
Published: December 2024

Günümüz koşullarında adolesanların günlerinin çoğunu evlerinin dışında geçirmeleri öğün atlamalarına ve yaşlarına uygun besin ögelerini yeterince tüketmemelerine yol açmaktadır. Sıklıkla hızlı ve pratik çözümler arayan adolesanlar ultra işlenmiş, paketlenmiş ve şişelenmiş hazır ürünlere yönelmektedirler. Bu derlemede piyasada günden güne artan enerji içeceklerinin içeriklerini ve etkilerini adolesanlar açısından ele almak amaçlanmıştır. İçerisinde yüksek miktarlarda kafein, şeker, taurin gibi bileşenler içeren enerji içeceklerinin adolesanlar arasında artan tüketimi endişe verici sonuçlar doğurmaktadır. Enerji içeceklerinin renkli, gösterişli ambalajları ve dikkat çekici isimleri de bu tüketim artışına katkı sağlamaktadır. Enerji içeceği bileşenlerinden kafeinin yüksek dozları ile ortaya çıkabilen akut kardiyovasküler yan etkileri ve depresyon, davranış değişikliği, şiddet, riskli davranışlara eğilim gibi uzun vadeli etkileri araştırılan konulardır. Üretici firmaların spor faaliyetleri ile enerji içeceklerini beraber pazarlaması da adolesanların bu içecekleri tüketmesine katkı sağlamaktadır. Ancak genç bireylerin bedensel ve zihinsel olarak sağlıklı gelişebilmesi için ihtiyaçları olan besin ögelerini yeterince tüketmeleri gerekmektedir. Sağlık durumuna ve gelişimlerine zarar verebilme potansiyeli olan hazır ve işlenmiş ürünlerden ise uzak durmaları ve bilinçlendirilmeleri önemlidir.
Effectiveness and Safety of Alternative Smoking Cessation Methods: The Dangers of Departure from the Traditional Approaches
Authors: Fidancı İzzet
Published: December 2024

This review article critically assesses the effectiveness and safety of the following alternative smoking cessation methods: electronic cigarettes, herbal supplements, acupuncture, compared with traditional approaches like nicotine replacement therapy, bupropion, and varenicline. Despite their increased popularity, most of these alternative methods are often lacking in robust scientific evidence and can pose serious health risks. It brought to the forefront case reports, studies revealing dangers, and high failure rates associated with these alternatives. Adhere to the time-tested, evidence-based traditional methods of smoking cessation.
Colisiones artísticas en el espacio educativo
Authors: Calviño-Santos Guillermo Francisco
Published: December 2024

Este artículo explora las colisiones estéticas presentes en el edificio de la Facultad de Ciencias de la Educación de la USC como una investigación artográfica que involucra al alumnado y el profesor de la asignatura de Procesos y estrategias en fotografía y arte contemporáneo del Máster Universitario en Investigación e Innovación en Didácticas Específicas para Educación Infantil y Primaria. La metodología de investigación se basa en la deriva estática siguiendo el modelo de Guy Debord mediante registro fotográfico. Las fases del proyecto incluyen la documentación teórica sobre deriva artística, el espacio educativo como tercer maestro y la percepción visual inspirada en el experimento literario Tentativa de agotamiento de un lugar parisino de Georges Perec. La fotografía se implementa como instrumento para documentar detalladamente el que ha sido el hábitat académico del alumnado durante cinco años. Seguidamente se crea un fotomontaje colectivo en el que las narrativas visuales se construyen mediante la interacción de texturas, colores, formas geométricas, elementos subjetivos, emocionales y críticos. La obra es el resultado de la deriva estática que muestra viajes texturales, ecos del espacio, geometrías efímeras y exploraciones cromáticas, revelando la lengua secreta del espacio compartido.
You Are Here
Authors: Soria Martinez Veronica
Published: December 2024

This article tells the story of how You Are Here came about, including its obstacles, pauses and reactivations. You Are Here is a piece of public art consisting of signs placed on the sidewalks of a neighborhood. Each sign contains a QR code that links to videos that narrate fictionalized memories that have to do with the public spaces of that neighborhood. The stories are based on personal memories, interviews with neighbors, and research into street names and the businesses that once existed on those streets. The listener must follow the route to access the stories, and thus, participate in the fabric of the microhistories that make up the identity of those spaces. This article explains how this artistic experience was developed and later adapted in the teacher training classroom.
A Menippean Marvel: John Fowles’s Mantissa
Authors: Akşehir Mahinur
Published: December 2024

Menippean satire, emerging in the 3rd century BCE, is a fluid, digressive genre that defies conventional definitions. Its adaptability across historical periods makes each example unique, often marked by cynicism, parody, and carnivalization. Menippean works question absolute truths through irony, challenging cultural, philosophical, and literary norms without providing alternative solutions. John Fowles's Mantissa (1982) exemplifies Menippean satire, exploring themes of metafiction, creative process, and literary theory. Through dialogues between author Miles Green and his characters, the novel blurs boundaries between reality and imagination. John Fowles' Mantissa challenges conventional fiction-writing through intertextuality, dialogy, and metafiction questioning the nature of existence, the boundaries between fiction and reality, and societal norms. The novel, through its playful, multilayered narrative, breaks binaries like sanity versus madness while satirizing traditional literary authority and high art conventions.
Impugnación indirecta de actos consentidos
Authors: Rebollo Puig Manuel
Published: December 2024

Se plantea si el recurso contra un acto administrativo puede basarse en la ilegalidad de otro acto que le da fundamento pero que no fue impugnado en su momento.Se analizan las sentencias del Tribunal Supremo que han dado diversas respuestas a la cuestión. Y, sobre esa base, se intenta finalmente una respuesta general que, en esencia, se construye sobre la distinción entre nulidad y anulabilidad.
El blindaje de las normas forales vascas: Del control exclusivo al control compartido
Authors: Coso Mateo Jorge del
Published: December 2024

La Ley Orgánica 1/2010, de 19 de febrero, de modificación de las leyes orgánicas del Tribunal Constitucional y del Poder Judicial, atribuyó al Tribunal Constitucional «en exclusiva» el control de las normas forales fiscales de los territorios históricos de Álava, Guipúzcoa y Vizcaya, apartando de su conocimiento a la jurisdicción contencioso-administrativa. Sin embargo, en 2016, el Tribunal Constitucional emitió una sentencia interpretativa que abría la puerta a un control compartido entre ambas jurisdicciones. En el presente trabajo se analizan tanto los motivos que impulsaron dicha reforma como sus consecuencias jurídico-constitucionales, especialmente a partir del pronunciamiento del Tribunal Constitucional, ofreciendo finalmente una visión general del control judicial de estas normas en la práctica jurisdiccional actual.
Los derechos fundamentales diacrónicos en la jurisprudencia europea de cambio climático
Authors: Ruiz Prieto Mario
Published: December 2024

El caso Verein KlimaSeniorinnen es el primero en el que el Tribunal Europeo deDerechos Humanos (TEDH) declara la violación del Convenio debido a la insuficiencia de objetivos de reducción de emisiones de Suiza. Ahora bien, su importancia doctrinal es aún mayor, dado que supone la consolidación de la doctrina de los derechos fundamentales diacrónicos en el contexto climático. El propósito de este trabajo consiste en exponer las características de la doctrina de los derechos fundamentales diacrónicos aplicada al cambio climático y su relación con el caso Verein KlimaSeniorinnen. Este último será analizado como un híbrido de los casos Urgenda y Neubauer al asumir las formas argumentales del primero y la argumentación material intergeneracional del segundo. Por último, examinaremos sus implicaciones respecto del derecho de la Unión Europea, el ordenamiento español y la normativa sobre calidad del aire.
Radioprotective effect of Umbelliferon Against Radiation-Induced Myocardial Damages
Authors: Dumlu Nurdan , Geyikoğlu Fatime , Çolak Suat
Published: December 2024

Radiation at a high dose may attenuate myocardial functions while presenting the therapeutic effect on cancer cells and thus can be life-threatening. Today, many studies reveal that supportive treatments provide important protective effects against acute radiation damage in vital organs including the heart. To our knowledge, the role of umbelliferone in the prevention of radiation damage to the heart has not yet been clarified. Therefore, the current study was planned to evaluate the role of umbelliferone radiation-induced cardiac injury using biochemical and histological data. Rats will be divided into eight different groups as control, radiation and treatment groups. No application was made to the control group. The second group animals were exposed to a single dose (12Gy) radiation throughout the body. Groups 3, 4 and 5 were orally given umbelliferone (25, 50 and 100 mg/kg) single dose for 3 days. Groups 6, 7 and 8 received umbelliferone and then radiation was applied. After the experiments, the myocardial tissues of the rats were removed and the protection of the substance against radiation was investigated. Radiation exposure to the rats induced oxidative stress, inflammation, pathological changes and vascular dysfunction in cardiac tissue. Whereas umbelliferone in high dose (100 mg/kg) pretreatment supported the anti-oxidant activity and also reduced the inflammatory response on heart tissue against radiation-associated toxicity. Besides, radiation-induced histopathological changes significantly ameliorated in umbelliferone-treated rat groups. Umbelliferone (100 mg/kg) pretreatment reduced radiation-induced heart damage, which was thought to provide the greatest opportunity for umbelliferone's efficacy as a new drug against the side effects of radiotherapy
Functional outcome of Schatzker type V and VI tibial plateau fractures managed by open reduction and internal fixation using dual plates
Authors: Haider M. Ali , Hossain M. Iqbal , Ahmed Wakil , Tuhin Jabed Jahangir , Paul Ratan Kumar , Hasan M. Rashed , Hasibuzzaman M.
Published: December 2024

Background: High-energy bicondylar tibial plateau fractures (Schatzker type V and VI) occur as a result of road traffic accidents, falls from height, and sports injuries, and mostly affect the younger age group in productive life years. This study aimed to evaluate the functional outcome of high-energy tibial plateau fractures (Schatzker type V and VI) treated by dual plating through anterolateral and posteromedial incisions.
Methods: This was a hospital-based clinical trial study conducted in the department of orthopaedics and traumatology, Chittagong medical college hospital, Chattogram, Bangladesh, from January 2018 to December 2019. Our study included 50 adult patients of both genders with high-energy tibial plateau fractures through a consecutive sampling technique. The knee function of the patients was evaluated according to the Oxford knee scoring system.
Results: Out of 50 cases, 38 cases (76%) were male and 12 cases (24%) were female with a mean±SD age was 43.95±10.89 years. All the cases (100%) were due to RTA, 70% had Schatzker type VI and 30% had type V injury. Mean±SD time interval from injury to fixation was 11.05±3.20. The average duration of operation in minutes was 107.0 (±12.07). At the final follow-up, 41 (82%) and 05 (10%) patients had excellent and good outcomes respectively.
Conclusions: Open reduction and internal fixation in high-energy tibial plateau fractures using dual plates through two incisions can provide excellent to good functional results and minimal soft tissue complications in appropriately selected cases.
Expert perspectives on polmacoxib monotherapy in the management of osteoarthritis in Indian settings
Authors: S. Manjula , Kumar M. Krishna
Published: December 2024

Background: Although there were several clinical studies available, there was a dearth of studies among clinicians in actual practice. So, the present survey-based study aimed to gather expert perspectives on the clinical use of polmacoxib monotherapy for the management of osteoarthritis (OA) in routine Indian settings.
Methods: This cross-sectional study employed a 19-item questionnaire to gather expert opinions on managing OA and covered topics such as prescription practices, clinical observations, preferences and experiences with polmacoxib for routine OA management. Descriptive statistics were used to analyze the gathered data.
Results: The study involved 239 participants, with 45% of respondents noting that 31-40% of OA patients are women. According to 65% of the participants, etoricoxib emerged as the most preferred nonsteroidal anti-inflammatory drug (NSAID) in clinical practice. Moreover, 87% of experts recognized the dual cyclooxygenase-2 (COX-2) and carbonic anhydrase (CA) binding properties of polmacoxib as potentially offering superior safety profiles in cardiovascular (CV), renal aspects and Gastrointestinal (GI) tolerability. Around 35% of respondents observed improvements in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain reduction, stiffness alleviation and enhanced physical function with polmacoxib.
Conclusions: The study highlighted a significant preference among Indian clinicians for polmacoxib in managing OA, primarily due to its dual COX-2 and CA binding properties that potentially offer better safety profiles in terms of cardiovascular, renal and GI tolerability. Additionally, the observed improvements in pain, stiffness and physical function with polmacoxib underscore its effectiveness as a monotherapy in routine OA management.
Staged tricortical bone graft with internal fixation in complex distal humerus fracture: a prospective study
Authors: Maheshwari Prince , Pushprajan  , Ojha Ankur , Singh Ajit , Kumar Satyam
Published: December 2024

Background: Complex distal humerus fractures present a significant challenge in orthopaedic surgery. This study evaluates the efficacy of staged tricortical bone graft combined with internal fixation in these fractures.
Methods: A prospective study involving 50 patients with complex distal humerus fractures treated with staged tricortical bone graft and internal fixation was conducted. The primary outcomes measured were radiographic union and functional recovery using DASH and MEPS scores over a 12-month period.
Results: Radiographic union was achieved in 100% of patients at 12 months. Significant improvements in functional outcomes were noted, with DASH and MEPS scores improving from 75.3 and 55.4 at baseline to 20.1 and 95.0, respectively, at 12 months (p<0.001). The complication rate included an 8% incidence of postoperative infection and a 6% rate of non-union. Subgroup analysis indicated slightly better outcomes in patients under 50 years.
Conclusion: Staged tricortical bone graft combined with internal fixation demonstrates high efficacy in treating complex distal humerus fractures, offering high union rates and significant functional improvements. While the results are promising, further research is needed for broader validation.
Use of palmaris longus graft in chronic distal radio-ulnar joint instability in complex tear of triangular fibro-cartilage complex
Authors: Gandhi Malay P. , Patel Nilkumar R. , Shah Rushit M. , Mehta Vatsal J. , Shah Malkesh D.
Published: December 2024

Chronic distal radio-ulnar instability often results from complex tear of triangular fibro-cartilage complex (TFCC), which serve as a critical stabilizer for wrist. This injury frequently arises due to repetitive trauma or acute injury, leading to significant pain, functional impairment, and diereses grip strength. Chronic dislocation of the distal radio ulnar joint has traditionally been managed through intricate osteotomies and reconstructive procedures, often resulting in stubborn stiffness and diminished functionality. It is advantageous to employ a fixation method that not only restores wrist biomechanics but is also aesthetically pleasing for the affected individual. Here, we introduce a new technique for use of palmaris longus graft with fixation button stabilizing chronic distal radio-ulnar joint instability. The advantage of this surgery is decries the duration of the surgery, and start early range of movements of wrist with significant improvement in pain using the vas score. None of the patients had complications. The use of palmaris longus graft is believed to an innovative, safe, reliable and efficient method for of distal radio-ulnar joint (DRUJ) instability.
Anatomical retinaculum repair and pseudo-pouch closure: surgical technique for management of posterior tibial tendon dislocations
Authors: Seiça Emanuel Cortesão , Gamelas João , Canhoto Joana , Vide João , Cardoso Afonso
Published: December 2024

This study aims to present a surgical technique for managing Type-II posterior tibial tendon (PTT) dislocations, characterized by a detachment of both the flexor retinaculum and periosteum from the tibia, and to review existing literature on treatment approaches for this rare condition. We describe a surgical procedure that involves an approach to the PTT, assessment, and potential deepening of the retro malleolar groove, and repair of the detached flexor retinaculum using a double suture technique. The technique addresses the challenges posed by the pseudo pouch formed due to the detachment and aims to stabilize the PTT within the groove. The surgical outcomes of two cases involving young, active patients are discussed, including pre- and post-operative assessments. In case 1, a 19-year-old male athlete demonstrated improvement in pain and function, with no recurrence of dislocation at six months follow-up. Case 2, a 40-year-old male athlete, experienced slight discomfort but returned to practice with improved strength and function. Both cases showed effective tendon stabilization within the retro malleolar groove and favorable outcomes without significant complications. The described surgical technique for Type-II PTT dislocations, involving reattachment and repair of the retinaculum, successfully addresses the challenges of the pseudo pouch and provides effective stabilization of the tendon. This approach results in satisfactory clinical and radiological outcomes, with most patients achieving a return to pre-injury function. The study highlights the need for further research to compare biomechanical effectiveness and long-term tissue healing outcomes of this technique.
Total knee arthroplasty in pigmented villonodular synovitis: a case report and its management
Authors: Kumar Anand , Rawat Sanjay Singh , Meena Ram Prasad , Karir Ekaansh
Published: December 2024

Pigmented villonodular synovitis (PVNS) is a benign yet potentially aggressive proliferative lesion of the synovium, which can lead to significant morbidity, particularly when associated with osteoarthritis. This case report presents a 48-year-old male with a 2-year history of knee swelling and pain, exacerbated over the last 6 months, resulting in impaired daily activities. Clinical examination and imaging revealed severe osteoarthritis and soft tissue swelling around the knee. Surgical intervention involved total synovectomy and total knee arthroplasty, performed concurrently. The patient exhibited favorable postoperative outcomes, achieving full range of motion and resolution of symptoms. This case underscores the importance of recognizing PVNS as a contributor to knee osteoarthritis and highlights effective surgical management strategies to improve patient quality of life. Follow-up care is crucial to monitor for potential recurrence of the disease.
Use of topical corticost eroids in dermatological conditions: data from real world
Authors: Nott Anand , Sakhiya Jagadish , Sharma Richa , Aich Biswajit , Muchhala Snehal Sameer , Katare Sagar , Sanghavi Arti , Reddy B. Swathi , Kotak Bhavesh P. , Pitalia Shraddha , Gudibanda Sandeep , Govindaraj Jayanthy
Published: December 2024

Background: Topical corticosteroids (TCS) are the first treatment option prescribed for various dermatologic conditions. When used as monotherapy or combination therapy, TCS can efficiently alleviate the symptoms of atopic dermatitis and psoriasis. This electronic medical records (EMR) based study was planned to evaluate the TCS usage pattern in atopic dermatitis and psoriasis.
Methods: This was a real-world, retrospective, cross-sectional, EMR-based study where anonymized data of patients diagnosed with psoriasis (≥18 years) or atopic dermatitis (all age groups) and prescribed with TCS from 2017-2023 was extracted from the EMR database for analysis. Demographic characteristics of patients (age, gender), duration of the TCS prescribed, comorbid conditions and the concomitant medications prescribed with TCS were evaluated.
Results: Monotherapy (single TCS) was the most preferred. Clobetasol propionate, mometasone furoate and desonide were commonly prescribed. For psoriasis, a combination of TCS with non-steroidal molecules was most preferred. The most prescribed was the fixed-dose combination (FDC) of clobetasol propionate and salicylic acid. Antihistamines and emollients were the most common concomitant medications prescribed for atopic dermatitis patients. Antihistamines and immunosuppressants were the commonly prescribed concomitant medications for psoriasis patients.
Conclusions: It can be inferred from the findings of the study that TCS remain the mainstay for the treatment of atopic dermatitis and psoriasis. TCS monotherapy was preferred for atopic dermatitis while combination therapy emerged as the preferred approach for psoriasis patients.
A case series of comorbidities seen in bullous pemphigoid
Authors: Koneru Yamini , Wilson Anushka , Patil Sharmila
Published: December 2024

Bullous pemphigoid (BP) is an autoimmune skin blistering disease commonly seen in the elderly which is associated with increased morbidity. The association of BP with comorbidities, especially cardiovascular, neurological, type 2 diabetes mellitus (T2DM) and has been seeing a rising trend in the recent years, not only with the underlying condition but also the drugs associated. A systematic literature review was conducted to identify and analyze the comorbidities prevalent in patients with BP.
Explorando a IA generativa nas escolas: aprimorando habilidades de interpretação de dados
Authors: Lisiak Caroline , Geltrudes Webber Carine
Published: December 2024

Este artigo apresenta a aplicação de modelos de Inteligência Artificial (IA) no ensino da disciplina de Estatística Básica para alunos do segundo ano do Ensino Médio. A atividade teve como objetivo principal desenvolver a habilidade de interpretação crítica de gráficos, explorando diferentes perspectivas de análise proporcionadas pelos modelos de IA Chat GPT e Gemini. A atividade, realizada em grupos, promoveu o aprofundamento da análise comparativa entre as interpretações produzidas pelos alunos e aquelas geradas pelos modelos de IA. O foco esteve na identificação de padrões, tendências e inconsistências, com vistas a enriquecer o aprendizado e estimular uma compreensão crítica dos dados. O debate final, ao comparar as análises realizadas pelos alunos e pelos modelos de IA, evidenciou a importância de múltiplas abordagens na interpretação de dados, consolidando uma experiência educativa inovadora e fortalecendo a integração entre os conteúdos de Estatística e as funcionalidades dos modelos de IA.
Concomitant benign serous cystadenoma with struma ovarii - An unusual combination of tumours from different origin, a case report and review of literature
Authors: Radhika S , T Anbu Muthamil  Nayahi , G Kavitha , Garg Nidhi
Published: December 2024

Struma ovarii is a rare ovarian tumour of germ cell origin which accounts for less than 5% of all ovarian neoplasms. It can occur alone or in association with other non-germ cell epithelial ovarian neoplasms. The coexistence of struma ovarii with serous cystadenoma is extremely uncommon with only 6 cases reported so far until 2017. Herein, we report an extremely rare case of a 39-year-old woman who presented with an ovarian mass. Clinicoradiologically possibility of a right ovarian cyst with torsion was made. Histopathological examination revealed an unusual dual pathology – benign serous cystadenoma and struma ovarii. This case is reported to highlight the importance of extensive sampling and careful histopathological examination even in a grossly benign looking cystic lesion of the ovary. This case is presented due to its extreme rarity which can cause diagnostic dilemmas and to provide insight into rare entities and its prognostic significance.
Soft tissue myoepithelioma arising over the scalp: Rare case report
Authors: Shrivastava Apurva , Bijjaragi Seema , Neethu G.V. , Kulkarni Vardendra , Chandrashekar H.R.
Published: December 2024

Myoepithelioma is a well-known tumour in the salivary glands and breasts in adults. It is exceptionally rare in soft tissue and in children.Myoepithelial tumours of soft tissue are categorised as tumours of uncertain differentiation (WHO Classification of Tumours 5ed-Soft Tissue and Bone Tumours). They are a group of uncommon neoplasms with equal sex predilection and a wide age range (median age:40years). These tumours show extensive spectrum of cytological, architectural, and heterogenous immunophenotypic profile.

This case report presents a 36-year-old male who visited surgery OPD with complaints of a gradually increasing painless swelling over the scalp for 5 years. Clinical examination showed a well demarcated, irregular, soft to firm, non-compressible and non-reducible swelling over left side of scalp measuring 11x3cm. No signs of inflammation/pulsations/punctum over the swelling. Skin over the swelling appeared normal. Pre operative diagnosis of venous malformation or sebaceous cyst was made. Radiological assessment was not done. Mass was excised keeping the capsule intact and the specimen was sent for histopathological assessment. Final diagnosis of Soft Tissue Myoepithelioma (Scalp) was made.Immunohistochemistry showed diffuse strong positivity for S-100 protein & myogenic marker Calponin.

Myoepithelial tumours of soft tissue arise on the limbs and limb girdles (75%; lower more frequently than upper); others arise on the trunk. They are rarely located over scalp (head & neck region). Myoepitheliomas lack tubulo-ductal differentiation histologically. Because of the variable appearance of myoepithelial cells and their phenotype, the histopathological diagnosis is challenging. Most myoepithelial tumours are benign, show indolent behaviour, rarely metastasize; showing recurrence in 20% cases. Myoepithelial carcinomas recur and metastasize (40-50% of cases); with disease related death in 13-43% of patients.

Therefore, prompt identification using histopathology and immunohistochemistry becomes necessary.
Photobiomodulation therapy for the management of acute radiation dermatitis in head and neck cancer: A case report
Authors: Khatri Rajkumari , Dharkar Dhigpal
Published: December 2024

To assess the effectiveness of photobiomodulation therapy (PBMT) for the management of acute radiation dermatitis (ARD) in a head and neck cancer (HNC) patient. This case study examines a patient who developed a severe radiation reaction during radiotherapy for squamous cell carcinoma of the alveolus, which was successfully managed with supportive care, including PBMT. PBMT significantly reduced grade IV ARD and grade III oral mucositis to grade zero within one week after the completion of radiotherapy. The patient completed treatment without interruption or hospitalization. PBMT appears to be a safe and effective method for managing severe ARD. The incidence of radiation dermatitis may be influenced by factors such as the type of radiation equipment used and whether concomitant chemotherapy was administered as an adjunct. More studies are needed to establish standardized PBMT protocols. 

This case study supports the implementation of PBMT in clinical oncology practice.
A gestão acadêmica em (trans)formação: princípios e oportunidades de inovação na gestão no cenário pós-crise
Authors: Vaz Douglas , Souza Renaldo
Published: December 2024

A gestão acadêmica permeia por abordagens que impactam a sociedade, trabalho e educação, na perspectiva de trazer aspectos relacionados aos desafios da gestão no contexto das universidades, permitindo-as refletir em relação à complexidade de suas atividades, tradicionalmente orientadas para as áreas do ensino, pesquisa, extensão e da gestão acadêmica e administrativa. Nesse sentido, este artigo tem como objetivo discorrer sobre a história e contexto universitário brasileiro, especialmente sobre a gestão acadêmica em (trans)formação, numa abordagem sobre princípios e oportunidades de inovação na gestão no cenário pós-crise. A metodologia de pesquisa adotada é bibliográfica, recorte de uma tese de doutorado, que reproduz reflexões sobre a gestão universitária na contemporaneidade e os princípios e oportunidades para uma nova gestão acadêmica. Os resultados da pesquisa corroboram com a necessidade de maior aprofundamento literário sobre gestão ágil e inovadora, demonstrando que os princípios adotados durante a pandemia foram fundamentais para a continuidade das atividades acadêmicas. Conclui-se que os princípios de agilidade, inovação e empatia emergem como pilares fundamentais para o futuro das instituições de ensino superior. Assim como a gestão empática, focada no bem-estar de toda a comunidade acadêmica, reforçou a importância de uma abordagem humanizada e acolhedora, essencial para fortalecer o engajamento e a colaboração entre estudantes, docentes e gestores.
Pedagogia universitária
Authors: Mendes Tomaz dos Santos Guilherme
Published: December 2024

O presente artigo, decorrente de uma pesquisa qualitativa, de abordagem qualitativa, com objetivo exploratório-descritivo, teve o estado da arte como procedimento técnico. O objetivo geral consistiu em analisar as teses e dissertações presentes no Catálogo Digital de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CDTD/Capes) que cunharam a pedagogia universitária em seu título e que focalizaram a docência universitária como eixo analítico-discursivo. O espaço temporal consistiu no período de 1987 a 2016. O corpus da pesquisa foi composto por 9 (nove) produções. Para a análise dos dados fizemos o uso da técnica da análise textual discursiva. Como principais achados da pesquisa, os resultados apontaram: a) a necessidade de fortalecimento da formação pedagógica para os docentes universitários; b) a importância do estágio de docência como um processo formativo e o impulsionamento de implementação de políticas institucionais; c) entre outros.
Vapor-Liquid-Liquid Equilibrium of Methanol, Cyclohexane, and Hexane Systems at 0.1 MPa: Binary and Ternary Phase Behavior Analysis
Authors: Gillani Q.F. , Askar P. , Ospanova A. , Jamali M.A. , Nuraje N.
Published: December 2024

This study presents an evaluation of the liquid-liquid equilibria (LLE) for both binary and ternary systems involving methanol, cyclohexane, and n-hexane at a pressure of 1 MPa. The investigation encompasses a comprehensive analysis of phase behavior, including thermodynamic modeling, and graphical representations. The binary system of methanol and cyclohexane is examined extensively to understand their phase equilibrium at varying temperatures, with a focus on the T-xx diagram, activity coefficient calculations, and vapor-liquid equilibrium (VLE) analyses. Furthermore, the ternary system incorporating n-hexane alongside methanol and cyclohexane is investigated to explore the intricacies of multicomponent phase behavior. Through the utilization of thermodynamic models such as the Non-Random Two-Liquid (NRTL) model and Universal Quasi-Chemical (UNIQUAC) model, key insights into the phase compositions, distribution coefficients, azeotropes, and residue curves are elucidated. The findings from this study provide valuable insights into the thermodynamic interactions within these systems, offering essential guidance for process design and optimization in various industrial applications.
Excitation energy transfer in europium complexes with doxycycline in the presence of surfactant micelles and silver nanoparticles
Authors:   Saratov State University, Danilina Tatyana G. , Syardina Alina V. ,   Saratov State University, Timonova Ekaterina R. ,   Saratov State University, Nevryueva Natalya V. ,   V. I. Razumovsky Saratov State Medical University, Smirnova Tatyana D. ,   Saratov State University
Published: December 2024

Doxycycline is a broad-spectrum tetracycline antibiotic used to treat infections in humans and in veterinary medicine as a
prophylactic drug and growth stimulant. For this reason, residual amounts of antibiotics in milk, meat and other food products can cause
resistance and the development of allergies. In this regard, constant monitoring of residual contents of tetracyclines in food products,
environmental objects, and biological fluids is required. The purpose of this work was to study the effect of spherical silver nanoparticles
and surfactant micelles on the intensity of sensitized fluorescence of europium ion complexes with doxycycline and to develop a new
sensitive and simple method for the fluorimetric determination of doxycycline in solutions. As a result of the simultaneous influence of
the energy of an external excitation source and the surface plasmon resonance of silver nanoparticles on doxycycline, the intensity of its
fluorescence increases. The probability of the ligand transition to the excited state increases significantly, which contributes to the most
efficient implementation of intramolecular excitation energy transfer in the Eu3+ complex with doxycycline. We have shown that in the presence of silver nanoparticles and Eu3+ ions, the fluorescence intensity of an analytical system containing doxycycline increases 125 times.
In the presence of the nonionic surfactant Tween-80, the sensitized fluorescence signal of the Eu3+ chelate with doxycycline increases by
more than 19 times. Solubilization of the components of the analytical reaction into micelles of surfactants helps to change their protolytic
properties, dehydration, increase the stability of the complexes, and the efficiency of intramolecular energy transfer. In the combined presence of Tween-80 surfactant micelles and silver nanoparticles, an additional 27-fold increase in the fluorescence intensity of the metal
ion chelate with doxycycline is observed. Based on the conducted research, a method for the fluorimetric determination of doxycycline
using Tween-80 micelles, silver nanoclusters and Eu3+ ions in natural water has been proposed. The range of detectable concentrations
is 1.0·10-7–1.0·10-5 M, detection limit (Limit of Detection) 6.0·10-8М (3 σ). The correctness of the definition has been controlled by the
“entered–found” method.
Influence of time factor on adhesion and electrosurface properties of conductor and dielectric after plasma chemical activation of surface
Authors:   Mari State University, Averina Alexandra I. , Kashirin Nikolay V. ,   Mari State University, Sidorov Ruslan V. ,   Mari State University, Khodataeva Tatiana S. ,   Mari State University
Published: December 2024

The paper presents the results of measuring the surface adhesion figures of a dielectric (non-foiled glass-cloth-base laminate) and a
conductor (foiled glass-cloth-base laminate) obtained by the adhesive tape tear-off method, as well as the surface potential depending on the time
of storage of samples in natural conditions after activation of their surface by plasma-chemical etching. The obtained dependences are complex
declining functions of time. We have attributed the jump in the adhesion figures of the activated surface, compared to the unactivated surface,
immediately after its activation to the acquisition of a developed morphology by the surface, and the jump in the potential to the acquisition of
surface charge. On the obtained dependences we have selected the initial and final areas, which we have approximated by empirical linear equations. By the intersection of the approximating lines we have determined the conditional times of transition from the initial fast-declining section
to the final slow-declining section. It has turned out that these times coincide for time dependences of the adhesion figures and potential for both
studied samples. A correlation between the parameters of the equations for the adhesion figures and surface potential is shown. An attempt is
made to explain the observed dependences by the acquisition of electric charge by the surface and adsorption of substance from the environment.
Photostimulation as a therapy method for spinal cord contusion while asleep and awake
Authors:   Saratov State University, Semyachkina-Glushkovskaya Oksana V. , Saranceva Elena I. ,   Saratov State University, Iskra Tatiana D. ,   Saratov State University
Published: December 2024

Traumatic spinal cord injury is one of the most complex problems in modern medicine, characterized by a significant number of
severe consequences and complications, development of traumatic spinal cord disease with a complex of structural and functional disorders
leading to limited self-care and mobility, persistent endocrine shifts and changes in internal organs and systems, loss of control of pelvic
functions, high mortality rates, and an extremely high level of social and psychological maladaptation of patients. Taking into account the
fact that lymphatic drainage processes in the brain are activated during sleep, attention was given to comparing the effects of phototherapy of injured spinal cord in mice receiving treatment while asleep or awake. Photobiomodulation therapy was used as an anti-inflammatory
and non-invasive treatment with minimal side effects. In the course of the study we established the presence of lymphatic structures in the
animals’ spinal cord tissues. In a number of phototherapeutic effects during sleep we observed the following: improvement of morphological
parameters of spinal cord tissues and activation of lymphatic drainage processes in the spinal cord.
Prevalence of Adherence to Anti-hyperlipidemia Medication Among Adults in the Gulf Cooperation Council: A Narrative Scoping Review
Authors: Amoodi Hajra H. , Ahmed Luai A. , Nauman Javaid , Rahma Azhar T.
Published: December 2024

Introduction: Hyperlipidemia, a silent asymptomatic disease, contributes significantly to cardiovascular disease (CVD) mortality and morbidity in the Gulf Cooperation Council (GCC) region. One of the facets of preventing CVD endpoint is medication adherence to lipid-lowering drugs (LLDs). Accordingly, this scoping review aims to explore the adherence to anti-hyperlipidemia medications among adults in the Arabian Gulf region.
Methods: Based on the Preferred Reporting Items for Systematic Reviews and Meta- Analyses guidelines, a literature search was conducted in Scopus, PubMed, Web of Science, and Google Scholar to screen for articles published from 2013 to 2023 reporting adherence or compliance to LLDs among adults aged 18 years or above with or without any co-morbidities in the GCC region. The quality of the paper was assessed using the AXIS checklist.
Discussion: The search yielded 139 articles, six meeting our inclusion criteria, all of which were cross-sectional. The researchers utilized varied measuring tools, resulting in heterogeneous results: good adherence in two studies, low adherence in three, and indefinite results in one. Younger age, polypharmacy, and female gender were the variables associated with higher drug noncompliance in one or more studies.
Conclusion: There is a research gap on anti-hyperlipidemia medication adherence in the Arabian Gulf region which calls for further research, especially higher evidence studies as no attempts have been made beyond the cross-sectional design. Public health implications of the results may include awareness interventions and cliniciandriven strategies to improve patient compliance.
Dubai Clinical Practice Guidelines for Autism Spectrum Disorder (ASD) in Children and Adolescents (from Birth to 18 Years of Age)
Authors: Albanna Ammar , Sultan Meshal , Derby Hanan , Arjamand Fekrya , AlShuaibat Suha , Alloub Zeinab , Al Hejailan Rasha , Kair Hawk , Helou Maya , Obaid Hanan Ali , Alrustamani Latifa , Muhsineh Shatha , Willis Sandra
Published: December 2024

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and communication, along with restricted interests and repetitive behaviors. It is a lifelong condition that can profoundly impact the individual, their family, and the community. Given that the etiology of ASD is multifactorial, and the rise in ASD prevalence internationally, establishing evidencebased clinical guidelines is critical. The UAE offers a range of services for children and adolescents with ASD with the aim to improve the quality of services within a comprehensive system of care. The Dubai Clinical Practice Guidelines for Autism Spectrum Disorder (ASD) in Children and Adolescents (from Birth to 18 Years of Age), Version 1 aims to provide clinical guidance to healthcare professionals involved in managing ASD based on the best available local and international evidence. ASD management approaches are ranked in these guidelines based on their strength and availability of empirical evidence to support them. The clinical guidelines shall be read in conjunction with any new empirical evidence that arises after 2021.
Katalog druków cyrylickich XV–XVII wieku w zbiorach Zakładu Narodowego im. Ossolińskich, opracowała Olga Tkachuk; przy współpracy Doroty Sidorowicz-Mulak (Wrocław: Wydawnictwo Ossolineum, 2022), 247 s.: il.
Authors: Voloshchenko Stanislav
Published: December 2024

Katalog druków cyrylickich XV–XVII wieku w zbiorach Zakładu Narodowego im. Ossolińskich, opracowała Olga Tkachuk; przy współpracy Doroty Sidorowicz-Mulak (Wrocław: Wydawnictwo Ossolineum, 2022), 247 s.: il.
La Revista Colombiana de Obstetricia y Ginecología: setenta y cinco años dedicados al registro de los avances en la salud, la obstetricia y la ginecología en Colombia
Authors: Gaitán-Duarte Hernando , Briceño-Morales Ximena , Grillo-Ardila Carlos Fernando , Rubio-Romero Jorge Andrés
Published: December 2024

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Comparative study of morphological aspects and oil composition of cashew nuts from nine localities in Ivory Coast
Authors: Djolaud Soro Kili Frédérique , Boukachabine Khadija , El-Antari Abderraouf
Published: December 2024

In an effort to contribute to the oil crops in Ivory Coast, the seeds of Anarcadium occidentale (cashew nuts) were studied. This crop has a high socio-economic importance in Ivory Coast, and the country is the first world producer, the production is mainly destined for export. A homogeneous and representative sample was taken from different producing regions. Biometric characteristics showed a variation in nut weight of between 5–7 g, with a very good number of nuts per kg which vary from 146 to 188 nuts per kg. Measurements ranged from 2.94–3.25 cm in length to 2.06–2.25 cm in width, with no significant differences between the studied regions. Chemical extraction of the oil by soxhlet revealed that the kernels were rich in fat content on average 31.13%; with a peroxide value ranging from 1.69–6.99 meq O2.kg−1 and maximum K232 of 2.32 and free acidity < 2 mg.g−1 KOH Cashew oil has an interesting chlorophyll content, like olive oil (0–10 ppm), which ranges from 2.62 to 8.12 ppm. This oil is rich in oleic acid (63.80%–67.46%), followed by linoleic acid (16.09%–19.59%), and has a low quantity of palmitic acid (7.62%–9.43%).