bluuebunny/crossref_metadata_2025 huggingface dataset:
MODEL PEMANASAN RUGBY BERBASIS PERMAINAN UNTUK KOP RUGBY UNIVERSITAS NEGERI JAKARTA
Authors: Ikbal Miftahudin  , Iwan Barata
Published: October 2024

Penelitian ini bertujuan untuk menghasilkan produk baru berupa model pemanasan berbasis permainan untuk Klub Olahraga Prestasi Rugby Universitas Negeri Jakarta. Pengambilan data dilakukan pada bulan Juli 2021 yang bertempat Di Kampus B Fakultas Ilmu Keolahragaan UNJ, Rawamangun, Kec. Pulo Gadung, Kota Jakarta Timur. penelitian ini merupakan penelitian Model dan Pengembangan yang bersifat deskriptif. Metode yang digunakan dalam penelitian ini adalah metode Research & Development (R & D) dari ADDIE, yaitu dengan membuat produk berupa model permainan dengan 5 (Lima) tahapan, yaitu 1.) Analisis (Analyze), 2.) Desain (Design), 3.) Pengembangan (Development), 4.) Pelaksanaan (Implement), 5.) Evaluasi (Evaluate). Populasi yang digunakan dalam penelitian ini adalah anggota Klub Olahraga Prestasi Universitas Negeri Jakarta yang berjumlah 12 orang sebagai subjek Uji Coba skala kecil (Praktek Lapangan). Uji validasi yang digunakan pada penelitian adalah dengan menggunakan uji justifikasi ahli, dimana model yang telah dibuat diuji cobakan, kemudian dikonsultasikan dan dinilai oleh para ahli sesuai dengan variabel yang terkait. Uji coba yang dilakukan dengan memberikan 15 model permainan yang telah dibuat peneliti untuk dianalisa dengan pengisian angket justifikasi oleh dosen ahli (expert judgment). Setelah divalidasi oleh dosen ahli maka hasil akhir dalam penelitian ini berupa 14 model permainan yang dianggap layak dan kemudian dilakukan uji coba. Model permainan ini nantinya dapat dijadikan sumber referensi bagi para pengajar dan pelatih Olahraga untuk meningkatkan aktivitas gerak pemanasan menjadi lebih variatif. Kesimpulan akhir yang diperoleh melalui penelitian ini adalah 14 model pemanasan berbasis permainan yang peneliti buat telah layak dilakukan serta digunakan.
MODEL PERMAINAN AKURASI LEMPAR PISAU PADA ANAK USIA 10 - 12 TAHUN
Authors: Anggi Dina Pratiwi  , Hartman Nugraha  , Aryati
Published: October 2024

Penelitian ini bertujuan untuk membuat model permainan akurasi lempar pisau pada anak usia 10–12 tahun. Pendekatan penelitian pengembangan model permainan akurasi lempar pisau ini menggunakan model penelitian dan pengembangan (Research and Development) dari ADDIE. Subjek pada penelitian ini adalah anggota PORLEMPIKA dengan jumlah 15 anak. Pada penelitian ini peneliti bekerjasama dengan satu dosen ahli, dan dua pelatih lempar pisau PORLEMPIKA sebagai expert judgement. Uji validitas yang digunakan pada penelitian ini adalah dengan menggunakan uji justifikasi ahli dan pelatih, dimana model permainan yang telah dibuat dan diuji cobakan kemudian dikonsultasikan serta dinilai oleh dosen ahli dan para ahli dalam bidang olahraga lempar pisau. Adapun tujuan dari penelitian ini adalah untuk membuat model permainan akurasi lempar pisau pada anak usia 10–12 tahun. Model permainan ini juga bertujuan untuk dapat dijadikan bahan referensi atau pedoman bagi para pelatih dalam melatih akurasi lempar pisau. Melalui uji validitas yang dilakukan dengan menggunakan uji justifikasi ahli dan pelatih, menghasilkan produk model membuat model permainan akurasi lempar pisau pada anak usia 10–12 tahun sebanyak 15 model permainan.
PERAN ORANG TUA DALAM MENDUKUNG PRESTASI OLAHRAGA ATLET KARATE LEBAH BUKIT WIRA SAMARINDA
Authors: Hidayat Taufik , Nanda Alfian Mahardhika
Published: October 2024

Tujuan dari penelitian ini untuk mengetahui bagaimana peran orang tua dalam mendukung prestasi olahraga atlet karate Lebah Bukit Wira Samarinda. Penelitian ini adalah penelitian deskriptif kuantitatif. Penelitian ini menggunakan survey sebagai metode dengan menggunakan angket sebagai teknik pengumpulan data. Populasi berjumlah 13 orang yaitu seluruh orang tua dari atlet karate Lebah Bukit Wira Samarinda. Sampel penelitian ini berjumlah 13 orang yaitu seluruh orang tua dari atlet karate Lebah Bukit Wira Samarinda dan menggunakan teknik total sampling. Teknik analisis data yang digunakan adalah analisis deskriptif yang dituangkan kedalam persentase. Dari hasil penelitian yang telah dikumpulkan, peran orang tua dalam mendukung prestasi olahraga atlet Karate Lebah Bukit Wira Samarinda berada pada kategori “sangat kurang” sebesar 8% (1 orang), “kurang” sebesar 23% (3 orang), “cukup” sebesar 31% (4 orang), “baik” sebesar 38% (5 orang), serta “sangat baik” 0%. Berdasarkan nilai rata-rata (mean) yaitu 143,86, bahwa peran orang tua dalam Mendukung Prestasi Olahraga Atlet Karate Lebah Bukit Wira Samarinda berada dalam kategori “cukup”.
Permainan Tradisional Dakon Dalam Kecerdasan Matematika Pada Anak Usia Dini di SD Negeri Ambon
Authors: Javira Radiyanti Wulandari  , Heni Pujiastuti
Published: October 2024

Permainan tradisional merupakan salah satu media pembelajaran yang digunakan dalam proses pendidikan anak usia dini. Permainan tradisional yang tepat untuk meningkatkan kecerdasan matematis anak adalah dengan menggunakan permainan tradisional dakon. Kegiatan ini merangsang sebagian perkembangan anak selain melestarikan permainan tradisional. Penelitian ini menggunakan pendekatan penelitian tindakan kelas kolaboratif.Dengan subjek yaitu peserta didik kelas V SD Negeri Ambon Kota Serang dengan berjumlah 22 Orang yaitu 8 siswa dan 14 siswi. Dengan menggunakan permainan dakon peserta didik sangat semangat dan senang untuk belajar matematika. Sehingga mereka lebih mudah dalam menerapkan materi pembelajaran menggunakan permainan tradisional dakon dan hasil yang diperoleh yaitu peserta didik meningkat setelah pembelajaran menggunakan Permainan Tradisional Dakon hingga pada siklus ke dua yaitu 45,98%. Selain itu, karena pembelajaran menggunakan permainan tradisional ini pula fikiran mereka sedikit demi sedikit terbuka bahwa matematika itu menyenangkan.
Implementasi Senam Tai Chi Lanjut Usia Terhadap Tingkat Kecemasan di Panti Sosial Tresna Werdha Budimulia 3 Jakarta
Authors: Shafira Aprilia  , Aryati  , Iwan Barata
Published: October 2024

Penelitian ini bertujuan untuk mengetahui tingkat kecemasan pada lansia melalui aktivitas senam Tai Chi pada lansia. Pengalaman senam Tai Chi merupakan kegiatan yang dapat dilakukan di dalam maupun di luar ruangan dengan melihat dan merasakan keberadaan sumber belajar yang lebih nyata. Aktivitas senam Tai Chi berperan dalam menurunkan tingkat kecemasan pada lansia. Senam Tai Chi berperan dalam mendorong lansia lebih aktif dan lebih rileks dalam kehidupan sehari-hari. Penelitian ini dilakukan di Panti Sosial Tresna Werdha 3 Jakarta Selatan dilakukan pada lansia dengan rentan usia 60-75 tahun yang berjumlah 20 orang.  Penelitian ini   menggunakan pendekatan kuantitatif, metode survei dengan desain penelitian pre-test post-test prosedur pengumpulan data menggunakan teknik observasi, wawancara dan dokumentasi yang digunakan menggunakan trianggulasih data sumber, teknik dan waktu. Hasil penelitian menunjukan bahwa aktivitas senam Tai Chi ternyata mampu menurunkan tingkat kecemasan dengan optimal jika lansia melakukan secara rutin. Setelah dilakukannya aktivitas senam Tai Chi dengan intensitas yang sesuai dengan kisi kisi instrument penelitian yang dibuat.
Study the Optical Properties of Transparent Epoxy Resin (Epoprimer) Plates
Authors: Hussin Suma.H.AL-Shaikh
Published: October 2024

حضرت الواح راتنج الايبوكسي في المختبر بخلط راتنج الايبوكسي (A) مع المصلب B)) بنسبة خلط(2:1)(A:B)  وبذلك تم صناعة(6)  الواح مختلفة السمك تتراوح بين . (0.95-5.8)mm
       درست الخصائص البصرية كالامتصاصية والنفاذية و الانعكاسية وفجوة الطاقة والفلورة لحساب الثوابت البصرية معامل الامتصاص و معامل الخمود و معامل الانكسار و للألواح جميعها .
      لقد أظهرت النتائج العملية انه بزيادة سمك الالواح تزداد شدة الامتصاص فعند سمك   (0.95-5.8)mmكانت شدة الامتصاص تساوي (0.20, 0.69)(a.u.) على التوالي , وان قمة الامتصاص لمادة الايبوكسي تقع عند المنطقة فوق البنفسجية و بالتحديد عند الطول الموجي (330 nm) وفجوة الطاقة (Eg=3.59 (eV) ) وتمتلك  الالواح نفاذية تتراوح بين (60-92)% في منطقة الضوء المرئي ومعامل الانكسار للايبوكسي (n=1.3)  والانعكاسية (R=20%) عند الطول الموجي يساوي  (330)(nm).
    من دراسة طيف الفلورة الناتج عن ازاحة طيف الامتصاص (ازاحة استوك) لالواح الايبوكسي النقي فيختلف بحسب سمك الالواح المستخدمة اذ تزداد الازاحة نحو الاطوال الموجية الاطول (ازاحة حمراء ) بزيادة  سمك  الالواح  كما أوضحت  النتائج  ذلك   فعند  الالواح بسمك (0.95, 3 ,5.8)mm كان مقدار ازاحة طيف الفلورة (ازاحة استوك) (100 ,131 ,140)nm على التوالي.
La aplicación de los itinerarios pedagógicos virtuales para la enseñanza de la Geografía: una propuesta metodológica
Authors: González Díaz Benjamín , Ruiz Fernández Jesús , González Díaz José Antonio
Published: October 2024

Los itinerarios pedagógicos favorecen el aprendizaje experiencial de los conocimientos geográficos a partir de la observación directa, la puesta en práctica de los conocimientos teóricos, la conciencia medioambiental y el manejo de habilidades cartográficas. Pese a constituir una herramienta con un potencial didáctico indiscutible, posee ciertas limitaciones en su aplicabilidad real como: la falta de presupuesto, el número limitado de fechas para su ejecución, las condiciones meteorológicas, la recopilación de los pertinentes permisos cuando se trabaja con menores de edad, la presencia de alumnado con algún tipo de discapacidad/problemas de movilidad, y los problemas de conectividad con el sitio a estudiar (entre otros). En la actualidad, la irrupción de distintas aplicaciones geomáticas en el ámbito de la Geografía nos brinda la oportunidad de adaptación de esta metodología pedagógica de reconocido prestigio al ámbito virtual, rompiendo así con las limitaciones que presenta su modalidad presencial. En este sentido, el presente trabajo constituye una propuesta metodológica apoyada en la herramienta Google Earth Studio, y tomando como ejemplo un itinerario desarrollado en la Sierra del Naranco (Oviedo).
Integrative multi-omics analysis reveals chrono-modulation by time-restricted eating ameliorates non-alcoholic fatty liver disease
Authors: Rong Shuang , Li Zhiming , Deng Yan , Sun Yuze , Zhen Hefu , Shi Zhiyuan , Xiao Weilong , Zhang Wenwei , Zhang Xiu-Qing , Lin Hongkun , Wang Ziping , Yi Haoran , Li Fengping , Nie Chao
Published: October 2024

ObjectiveTo assess the impact of early and late time-restricted eating (eTRE and lTRE) on non-alcoholic fatty liver disease (NAFLD) and its underlying mechanisms involving gut microbiota and serum metabolome changes.
DesignThis 8-week randomized clinical trial involved 40 NAFLD patients divided into eTRE (8:00 am to 4:00 pm) and lTRE (12:00 pm to 8:00 pm) groups, with unrestricted caloric intake within these windows. Comprehensive analyses including nutrient intake, gut microbiota composition, serum metabolome profiling, and phenotypic assessments were conducted pre- and post-intervention.
ResultsBoth eTRE and lTRE significantly improved liver fat levels, visceral fat, body fat percentage, and body mass index (BMI). eTRE led to more pronounced changes in dietary patterns and exhibited a stronger influence on gut microbiota composition and the serum metabolome than lTRE. Notably, TRE increased the abundance of Enterocloster asparagiformis, a beneficial microbe linked to positive shifts in NAFLD phenotypes. This bacterium's presence was significantly associated with reduced levels of branched-chain amino acids (BCAAs) in both human subjects and mouse models, correlating with reductions in liver fat content, suggesting a metabolic modulation pathway. Metabolomic analysis further revealed significant alterations in amino acids and bile acids, which correlate with key NAFLD markers.
ConclusionTime-restricted eating (eTRE and lTRE) provides a viable non-pharmacological strategy for NAFLD management by altering gut microbiota and serum metabolomics. The differential effects of eTRE versus lTRE highlight the importance of meal timing in dietary interventions, supporting personalized dietary strategies based on individual responses to optimize NAFLD outcomes.
Trial registration number ChiCTR2100052876.
Extrapulmonary hamartoma
Authors: Huang Shaoqing , Li Jie
Published: October 2024

Pulmonary hamartomas are common. However，extrapulmonary hamartomas are very rare. We treated a patient with a pulmonary nodule at the left lower lobe by uniportal video-assisted thoracoscopic wedge resection, which showed a yellow nodule located on the visceral pleura. Pathology showed that the nodule contained a small amount of cartilage tissue and was diagnosed as hamartoma. Extrapulmonary hamartoma of this morphology has not been previously reported.
Clinicopathological and Imaging Characteristics of EBV Positive Inflammatory Follicular Dendritic Cell Sarcoma
Authors: Zhao Jie , Wang Kun , Liu Xiaoying , Zeng Xuemei , Li Yanchun , Zeng Yuli , Tan Xianzheng , Yang Hong
Published: October 2024

Objective
EBV-positive inflammatory follicular dendritic cell sarcoma (EBV + inflammatory FDCS) is a rare tumor that has been less systematically studied. This study aims to improve the understanding of EBV + inflammatory FDCS by analyzing radiological imaging data and clinicopathological features.
Methods
A retrospective analysis was performed on twelve patients with EBV + inflammatory FDCS confirmed pathologically. Ten patients underwent computed tomography (CT) scans, six underwent magnetic resonance imaging (MRI) scans, and four patients underwent CT and MRI scans simultaneously.
Results
Twelve patients (six in the liver and six in the spleen) had clinically asymptomatic or asymptomatic, and six cases were found on physical examination. Pathologically, the tumor cells dispersed in a background of inflammatory cells. All cases showed positive expression of at least one follicular dendritic cell (FDC) marker and EBV. On unenhanced CT images, nine cases of EBV + inflammatory FDCS presented as well-defined iso-or hypodense masses, and one liver case had an irregularly shaped lesion with unclear borders. All cases showed iso-or hypodensity signals on T1WI and mixed signals on T2WI. The hepatic lesions showed marked enhancement in arterial phase and diminished enhancement in portal vein phase and delayed phase, whereas the splenic lesions showed mild enhancement in arterial phase and continued enhancement in portal vein phase and delayed phase .
Conclusion
EBV + inflammatory FDCS is a rarely low-grade malignant tumor, which exists the possibility of local lymph node metastasis and recurrence. Therefore, the preoperative diagnosis is expected to improve by carefully analyzing the imaging features and clinical characteristics of the patients.
Earlier planting in a future climate fails to replicate historical production conditions for US spring wheat.
Authors: Savalkar Supriya , Pumphrey Michael , Campbell Kimberly , Scarpare Fabio , Ferdousi Tanvir , Swarup Samarth , Stöckle Claudio , Rajagopalan Kirti
Published: October 2024

Global warming can increase crop heat stress exposure, adversely affecting crop yields and quality. Earlier planting is widely considered in climate change literature as a potential adaptation strategy by shifting the growing season to cooler periods. However, the effectiveness of earlier planting in achieving overall temperature exposures during the crop growth season that are at least as favorable as historical conditions remains unclear. Our objective is to comprehensively assess the potential effectiveness of earlier planting as an adaptation strategy by addressing two key questions: How effective is earlier planting in reducing exposure to excessively high temperatures across different growth stages? What are the associated tradeoffs in temperature exposure, and can historical conditions be matched with this adaptation strategy? We focus on major US spring wheat growing states as a case study, analyzing lethal, critical, suboptimal, and optimal temperature thresholds by growth stage to quantify the impact of earlier planting. Our findings indicate that while earlier planting does reduce exposure to critical and lethal high-temperature categories during some reproductive stages, it generally fails to replicate historical production conditions for the majority of the US spring wheat production region (contributing 85% of the current production). This trend persists across all future time frames and emission scenarios. The Pacific Northwest US presents an exception; however, even in this region, certain early and late growth stages may experience worse-than-historical conditions requiring management. The planting window with historically equivalent temperature exposures also narrows from 11 weeks to 1-7 weeks, presenting additional logistical challenges. Given that the Pacific Northwest US accounts for less than 15% of the national spring wheat production, at a national scale, current production levels are unlikely to be sustained by primarily relying on earlier planting as an adaptation strategy. This is a critical consideration, especially given that many climate change assessments frequently list earlier planting as an effective adaptation strategy without the capacity to fully explore its tradeoffs. Exploring additional adaptation strategies to maintain current national production levels is important.
The Effect of Microplastics on Microbial Succession at Impaired and Unimpaired Sites in a Riverine System
Authors: Gilewski Anne L. , Shrestha Saurav , Kahara Sharon N. , Stasulli Nikolas M.
Published: October 2024

Background
Studies into biofilms and interactions with anthropogenic substrates like microplastic polymers are predominantly represented in the literature concerning marine environments. Less is known about microplastics in riverine environments that feed the microplastic accumulation of marine environments, transporting potentially harmful or pathogenic organisms that have accumulated on the microplastics. Environmental nutrient loads, seasonality, and geography are all known to influence microbiome formation. This project compared the microbial diversity of biofilms that developed on microplastics to natural stone substrates in an impaired and unimpaired section of the Quinnipiac River Watershed. We evaluated microbial diversity and composition via 16S rRNA gene sequencing while monitoring total colony and fecal coliform colony counts using standard water monitoring methods.
Results
Total coliform colony counts were higher in the impaired Quinnipiac River than in unimpaired Honeypot Brook (W = 583, p = 0.037) and on the microplastic substrate than stone substrate (W = 1038, p = 0.022). Sequenced features to the class level were dominated by Alphaproteobacteria, Betaproteobacteria, and Gammaproteobacteria, comprising 75% of the community biome. Simpson’s Diversity indices indicated that within the two substrates, there was little variation in the features present. However, it was noted that microplastic alpha diversity trended slightly lower than the stone. Further analysis of common aquatic enteropathogens showed that the genera Citrobacter was significantly more abundant on the microplastics at both locations.
Conclusions
Our results indicate impaired waterbodies with a microplastic burden may retain greater fecal coliform bacterial loads than unimpaired waterbodies. Increased microplastic loads in compromised lotic systems may have an additive impact. Water quality remediation and careful monitoring are recommended to reduce this effect. Comparing this study with environmental community analysis could provide valuable insight into preferential surface attachment of bacteria onto microplastic.
First indisputable fossil Ilex (Aquifoliales: Aquifoliaceae) flower found in Baltic amber
Authors: Rasmussen Finn N. , Johansen Bo , Dollman Kathleen , Wisaeus Erik , Vilhelmsen Lars
Published: October 2024

The genus Ilex (holly) in the monotypic family Aquifoliaceae contains more than 600 species distributed worldwide. Pollen fossils and macrofossils of fruits of Ilex are known from the late Cretaceous (90 Ma) and verified leaves from upper Miocene (10 Ma), but until now only a few more or less incomplete flower fossils have been suggested as referable to this genus. This paper reviews the fossil flowers earlier attributed to Ilex and presents a complete and indisputable staminate Ilex flower from Baltic amber (34–38 Ma) examined in fine detail with Synchrotron X-ray tomography. This find may challenge the hypothesis of a late Neogene dispersal of the genus from a center of origin in subtropical East Asia.
Sliding Characteristics of Chute Waste Slag in High Steep Canyon Ecologically Sensitive Areas
Authors: Chen Peishuai , Chen Fuxiang , Li Dejie , Xiao Jing , Zhu Juntao , Zeng Xutao , Zhang Shichao
Published: October 2024

To address the significant ecological impact caused by constructing access roads for tunnel excavation in steep and rugged canyon areas, a novel method is proposed in this paper. This suggests that waste slag materials are rapidly transported through an elongated chute attached to the mountain surface. This study utilizes theoretical analysis, on-site experiments, and numerical simulations to investigate the sliding characteristics of elongated chutes for efficient waste slag disposal. Through theoretical analysis to determine the friction coefficient of the discarded slag in the chute, with the help of field tests to optimize the design of the chute structure, numerical simulation was used to verify the reasonableness of the spacing arrangement of the fishbone-shaped baffle plate. The results reveal the following: (1) Increasing waste slag particle size decreases the waste slag's specific surface area per unit volume, reducing friction between the waste slag and the chute. The sliding speed of waste slag from the bottom opening of the chute gradually increases as the particle size increases. For waste slag particle sizes ranging from 10–20 cm, the friction coefficients range from 0.09 to 0.23, with an average of 0.16. (2) The sliding speed of waste slag inversely correlates directly with the length of the chute's zigzag structure and with the angle. Based on on-site experimental results, it is recommended that the zigzag structure length be 2 m and that the angle be set at 120°. (3) As the spacing between the fishbone-shaped baffles inside the chute increases, the force on the individual baffle structures gradually increases. The difference in the resultant force acting on the baffles in the 100 m segment before and after the chute also gradually increases.
Dual-Mode Temperature Monitoring Using High-Performance Flexible Thermocouple Sensors Based on PEDOT:PSS/CNTs and MXene/Bi₂Se₃
Authors: Xu Gaobin , Sun Baichuan , yang Zhaohui , Guan Cunhe , Ji Xu , Chen Shirong , Chen Xing , Ma Yuanming , Feng Jianguo
Published: October 2024

Due to the limited thermoelectric (TE) performance of polymer materials and the inherent rigidity of inorganic materials, developing low-cost, highly flexible, and high-performance materials for flexible thermocouple sensors (FTCSs) remains challenging. Additionally, there has been limited exploration of dual-mode (contact/non-contact) temperature monitoring in FTCSs, with most studies focusing solely on contact-based monitoring. This study addresses these challenges by using p-type (PEDOT:PSS/CNTs, 2:1) and n-type (MXene/Bi₂Se₃, 2:1) TE materials, applied through screen printing and compression onto a PPSN substrate (paper/polydimethylsiloxane (PDMS)/Si₃N₄). The resulting FTCS demonstrates excellent TE properties, with electrical conductivities of 61,197.88 S/m and 55,697.77 S/m, Seebeck coefficients of 39.88 μV/K and -29.45 μV/K, and power factors (PF) of 97.66 μW/mK² and 55.64 μW/mK² for the n/p-type materials, respectively. The sensor achieves outstanding performance in both modes: in contact mode, it exhibits high temperature sensitivity (S_T=376.1 μV/°C), a broad detection range (20-200°C), high resolution (~0.4°C), and fast response (~12.6 ms); in non-contact mode, it maintains relatively high sensitivity (S_Tmax=50.67 μV/°C), broad detection range (20-200°C), high resolution (~0.9°C), and even faster response (~9.8 ms). The sensor also shows strong resistance to mechanical deformation, maintaining stable performance after 1,000 bending cycles. When applied to dual-mode temperature monitoring in wearable devices and lithium batteries (LiBs), the FTCS not only shows high accuracy and reliability compared to commercial K-type thermocouples but also demonstrates the versatility needed for various applications. This suggests significant potential for integration into advanced medical monitoring systems and next-generation smart home technologies.
The Diagnostic Accuracy of Skin Diseases Via Teledermatology – A Single Center Study
Authors: Saade Serena , Khoury Dana Maria , Shahla William Abou , Stephan Carla , Charbel Nicole , Joukhdar Ronny , Bejjani Martine El , Bekdache Mira , Mansour Sara , Saade Dana
Published: October 2024

Background:
Teledermatology emerged as a safe tool that could fill healthcare gaps in underprivileged remote areas.
Objective:
To compare the diagnostic accuracy of teledermatologists with in-clinic dermatologists and assess various methods of photo capturing skin lesions, for better incorporation of teledermatology into clinical practice.
Methods
A single center randomized prospective trial at the American University of Beirut Medical Center involved adult participants seeking dermatologic consultation. Three sets of photographs were taken: patient-taken without guidance/unassisted, patient-taken with guidance/assisted, and resident-taken.
Results:
Diagnosis match with in-clinic visits increased from patient-unassisted (79%) to patient-assisted (84%) to resident-taken photographs (87%). Similarly, treatment match increased among the 3 modes respectively (38%,44% and 45%) and need for history decreased among the 3 modes respectively (64%, 59%, and 47%). Acne cases had higher diagnosis matches than malignant tumors and papulosquamous dermatoses among the three modes.
Conclusion:
A limitation of this study was the reliance on in-clinic expert opinions as “true diagnosis or treatment” for comparison purposes. Teledermatology’s accuracy in diagnosing common dermatoses, coupled with proper patient education on picture taking holds promise in its integration into clinical practice.
The impact of Mycoplasma pneumoniae infection on children with immune thrombocytopenia treated with thrombopoietin receptor agonists: a real-world study from China
Authors: Wang Nan , Wang Zhifa , Ouyang Juntao , Ma Jingyao , Wei Yunyun , Hu Yu , Liu Jingjing , Dong Shuyue , Meng Jinxi , Cheng Xiaoling , Wu Runhui
Published: October 2024

Mycoplasma pneumoniae (M. pneumoniae), as one of the susceptible pathogens during childhood, may lead to severe mycoplasmal pneumonia and even pulmonary embolisms, which could affect platelet count and increase the risk of thrombosis in patients who used thrombopoietin receptor agonists (TPO-RAs) treatment. We prospectively collected data on persistent/chronic ITP children prescribed TPO-RAs during the M. pneumoniae infection from August 2023 to December 2023. There were 33 patients enrolled (21 males), with a median age of 7.69 years (range 4.94 to 10.99). Before the start of M. pneumoniae infection, 54.5% of patients (18/33) were treated with eltrombopag, 36.4% (12/33) with avatrombopag, 6.1% (2/33) with hetrombopag, and 3.0% (1/33) with romiplostim. In our study, 63.6% (21/33) of the patients showed a transient decrease in platelet count, while 36.4% (12/33) showed a transient increase. Thrombocytosis was observed in 5 patients. One patient who used eltrombopag presented with a headache for 3 days and was diagnosed with cerebral sinus thrombosis during M. pneumoniae infection. In conclusion, the effect of M. pneumoniae infection on PLT is bidirectional and unstable, and the risk of thrombosis may be increased, especially in TPO-RA-treated patients.
Species diversity of genera Peronia, Wallaconchis and Onchidella (Gastropoda: Onchidiidae) in intertidal coral reef environments of the Ryukyu Islands
Authors: Mizukami Iori , Fourreau Chloé Julie Loïs , Castelló Guillermo Mironenko , Yafuso Nanami , Reimer James Davis
Published: October 2024

Three genera of the family Onchidiidae, Peronia, Wallaconchis and Onchidella, are known to inhabit intertidal coral reef environments in the Ryukyu Islands, however, there have been only limited studies on their diversity. This study conducted surveys around 11 islands and 40 intertidal areas of the Ryukyus, elucidating species diversity utilizing DNA barcoding of specimens. Molecular data indicated that intertidal coral reef areas of the Ryukyu Islands harbor at least eight Onchidiidae species from three genera. The highest species cohabitation in the same intertidal areas was observed around Okinawa-jima Island; five species from three genera. Peronia spp. were found from all sites investigated in this study and the distribution ranges of four species of Peronia in the Ryukyu Islands were updated from past research. Three species of Wallaconchis; W. ater, W. nangkauriensis, and Wallaconchis sp., were found in intertidal coral reef environments, mostly in flat areas with small rubble and rocks. Onchidella sp. inhabited intertidal areas and was found on many more islands of the Ryukyus than previously had been documented. All Onchidella sp. specimens collected from the Ryukyus were genetically distinct from described species. This study enhances the understanding of Onchidiidae diversity in intertidal coral reef environments of the Ryukyu Islands, providing a baseline dataset for better conservation of this understudied group.
Pathogenic germline variants in patients with early-onset colorectal cancer according to phenotype.
Authors: Benusiglio Patrick , Dardenne Antoine , Dhooge Marion , Basset Noemie , Chansavang Albain , Metras Julie , Farelly Solenne , Coulet Florence
Published: October 2024

We assessed retrospectively the prevalence of pathogenic germline variants (PGVs) in 271 French adult patients diagnosed with colorectal cancer (CRC) before age 41, stratified by phenotype. APC, BMPR1A, CDH1, EPCAM, MLH1, MSH2, MSH3, MSH6, MUTYH, POLE, POLD1, PTEN, PMS2, SMAD4, and STK11were analysed. Overall, 21.4% of cases carried a PGV. A high prevalence was observed in Mismatch Repair-deficient (MMRd) CRC (59.7%, MMR genes) and CRC associated with polyposis (48%, APC, biallelic MUTYH and MSH3, POLE). In contrast, MMR-proficient, non-polyposis cases only had a 1.7% prevalence. The only gene involved in this third group was POLE, and two out of three cases had either two synchronous CRC or a CRC family history. PGV prevalence is dependent on CRC phenotype, questioning the need for systematic germline testing in early-onset cases. A more targeted approach, focusing on MMRd CRC, or CRC associated with polyposis, might be warranted.
Magnitude and Determinates of Anemia among adolescent Girls in Africa: A Multilevel, Multicounty Analysis of 24 Countries
Authors: Tiruneh Fentanesh Nibret , Ejigu Bedilu Alamirie
Published: October 2024

Introduction: Anemia in Africa is a pressing public health issue with far-reaching consequences. Adolescents, especially girls, are more vulnerable to developing anemia due to rapid physical growth and development, menstruation and poor diets. Identifying the determinants of anemia among adolescent girls in Africa is crucial for developing appropriate interventions, yet evidence remains scarce. Objective: This study aims to investigate the magnitude and determinants of anemia among adolescent girls in Africa. Methods: Data from the recent Demographic and Health Surveys (DHSs) of 24 African countries was used, focusing on 38,966 adolescent girls aged 15–19 years. The chi-squared test was utilized for bivariate analysis, and the relationship between predictor variables and anemia was evaluated using bivariate and multivariable binary logistic regression models. Results: The overall magnitude of anemia among adolescent girls was 43.6% (95% CI: 42.97, 44.21). The research has identified several determinants associated with anemia in adolescent girls, including education status, wealth status, contraceptive use, nutritional status, pregnancy status, and net use. These factors provide valuable insight into potential avenues for intervention and prevention efforts. The multivariable analysis indicated that education status (primary education AOR = 0.72; 95% CI = 0.50–0.80 and secondary education AOR = 0.76; 95% CI = 0.66–0.86), wealth status (being rich AOR = 0.86; 95% CI = 0.76–0.98), contraceptive use (AOR = 0.46; 95% CI = 0.40–0.53), and nutritional status were inversely associated with adolescent anemia. In contrast, pregnancy status (AOR = 1.13; 95% CI = 1.01–1.27) and treated net use (AOR = 1.26; 95% CI = 1.15–1.39) were positively associated with anemia among adolescent girls. Conclusion: This study serves as a catalyst for informed action and underscores the urgent need for comprehensive interventions aimed at addressing the multifaceted determinants of anemia among adolescent girls in Africa. By targeting these key factors, public health initiatives can make significant strides towards improving the health and well-being of young women across the continent. To prevent adolescent anemia, it is recommended to encourage girls to pursue education, prevent adolescent marriage and pregnancy promote contraceptive use among married or sexually active girls, and educate on the correct use of treated nets.
Local and non-local chemical potential and hardness: A grand canonical ensemble approach
Authors: Zerón Paulino , Pantoja-Hernández Maurizio A. , Franco-Pérez Marco , Gázquez José L.
Published: October 2024

Context
The formulation of conceptual density functional theory in the grand canonical ensemble provides a theoretical framework that allows one to establish additional insights about the response functions that characterize this approach. In particular, through this procedure one can establish the local counterpart of the chemical potential which, when integrated over all the space, leads to the global quantity, and the local counterpart of the hardness that not only provides a function free of ambiguities, but also generates through its integration over all the space the well-defined value of the global quantity given by the difference of the vertical first ionization potential and electron affinity. In the present work the non-local counterpart of these local reactivity descriptors are derived making use of the Fukui kernel descriptor previously developed by us. Then, the local and non-local chemical potential and hardness thus obtained, are applied to study site and bond reactivities of several systems, to rationalize the behavior of kinetic and thermodynamic properties, through the chemical information that these indexes provide.
Methods
The electronic structure calculations required to evaluate the reactivity indexes analyzed in this work were done with the PBE0 exchange-correlation energy functional. The geometry optimization was done in all cases in a modified version of the NWChem program, while the Hirshfeld population analysis was done in a modified version of the demon2k program. For the electrophilic addition of hydrogen halides (HX) to several substituted ethenes and the hydration reaction of aldehydes and ketones the 6-311G** basis set was used, while for the bond enthalpies of chemical reactions where there is a homolytic bond break, and the trans influence in which the lability of the leaving ligand is modified by the ligand opposite to it, the Def2-TZVP was used.
Perception, travel satisfaction associated with the use of electric moped scooters: Evidence from Suzhou, China
Authors: Liu Jiayi , Guo Jia , Li Ruoning , Xu Jue
Published: October 2024

Electric moped scooters have rapidly emerged as the preferred mode of transportation for short-duration travelers, owing to their compact size, reliability, convenience, and cost-effective. As one of the most popular short-duration transport modes in China, however, only very few studies have explored the relationship between commuting satisfaction, users perception, socio-demographics, and usage of the e-moped scooter. What is more, there is a dearth of research on the usage frequency of e-moped scooter for various travel purposes. In practice, individuals often consider their travel needs and objectives when selecting a mode of transport. Thus, to investigate the factors influencing the usage of e-moped scooter, a survey was conducted in Suzhou, China. Generalized ordered logit models were employed for the analysis. The findings suggest that the satisfaction with reliability and driving speed significantly influences the usage of e-moped scooter for commute among frequent users. However, the perception of time-saving has a negative impact on the usage frequency in frequent electric moped scooter users for commute. Moreover, no significant effect of the satisfaction with reliability and driving speed, and the perception of time-saving are found on the use frequency of e-moped scooters for both shopping and recreational activities. By examining the determining factors that influence the utilization of electric moped scooters for various travel purposes, we can enhance individuals' acceptance of this transport mode and promote the development of e-moped scooters in China, and targeted practical implications were given in this study.
Dehydration of Cloudy-diesel Using Poly(Acrylamide-co-sodium Polyacrylate) Hydrogel Grafted Onto Cellulose
Authors: Perez Isadora Dias , Estevam Bianca Ramos , Soares João B.P. , Vieira Melissa Gurgel Adeodato , Fregolente Leonardo Vasconcelos
Published: October 2024

This article discusses the synthesis and application of a novel hydrogel to remove water from diesel. The poly(sodium acrylate-co-acrylamide) grafted onto cellulose hydrogel combines natural and synthetic polymers in a single novel formulation. The synthesized of the hydrogel was evaluated using a 23 full factorial design with two initiation methods (redox or thermal), two cellulose types (cellulose nanocrystal - CNC or hydroxyethyl cellulose - HEC) and two cellulose loadings (4 or 10%) as independent factors. The hydrogel swelling degree and final water concentration on diesel were used as responses. The best performing hydrogel was made with CNC using the redox initiation system. This hydrogel was further analyzed for its kinetic of water uptake from diesel and compared with ungrafted poly(sodium acrylate-co-acrylamide) hydrogels for their maximum swelling degree and water removal from diesel. The cellulose loading on the hydrogel was not found to be significant for the analyzed conditions. The cellulose-grafted hydrogel made with 4% CNC using the redox system achieved a swelling degree of around 139 g.g− 1 and reduced the water content in diesel from 5,000 to 150 mg.kg− 1. Compared to pure ungrafted hydrogel, the cellulose grafted hydrogel swelled less but removed more water from diesel. The hydrogel treatment also reduced the fuel turbidity and made it more compatible with standard requirements. This work demonstrates the successful synthesis of hydrogels of poly(SA-co-AAm) grafted onto cellulose and proves that these novel hybrid compounds can be used as fuel desiccants.
Recurrence Rate of Diabetic Ketoacidosis in A Year and Its Predictors among Diabetes Millets Patients Who are on Follow-Up at Public Hospitals in Bahir Dar City, Bahir Dare, Northwest Ethiopia, 2024, A Retrospective Follow up Study
Authors: Tadlo Asnaku , Wudie Gebiyaw , Gezachew Beselam , Habitamu Desyalew , Lidetu Tadios
Published: October 2024

Background: Diabetic ketoacidosis is an acute life-threatening complication of diabetes mellitus. Different literature showed that many diabetes mellitus patients develop diabetic ketoacidosis frequently. However, there is scarcity of updating data on the recurrence of diabetic ketoacidosis and its predictors among diabetes mellitus patients in Amhara Regional State, Ethiopia.
Methods and Materials: An institution based retrospective follow up study design was conducted and 378 charts of diabetic patients were selected through a systematic random sampling technique. Data were entered using Epi Data version 4.4.6 and then exported to STATA for the final analysis. Negative binomial regression model was used at a 95% confidence level. Statistical significance of the predictor on outcome variables was declared at P-value less than five percent (< 0.05).
Results: In this study, 378 charts reviewed. The mean recurrence of diabetic ketoacidosis was 0.63. This study found that being female (AIRR = 1.57, 95% CI 1.18- 2.07), type one diabetes mellitus (AIRR = 0.37, 95% CI 0.23- 0.57), longer duration of diabetes mellitus (AIRR = 2.36, 95% CI 1.27- 2.91), acute infection (AIRR = 4.33, 95% CI 2.75- 6.83), comorbidity (AIRR = 1.58, 95% CI 1.18- 2.09), injection type of treatment (AIRR = 0.65, 95% CI 0.44- 0.96) and mixed type of treatment (AIRR = 2.04, 95% CI 1.30- 3.2) were risk factors and medication compliance (AIRR = 0.23, 95% CI 0.17- 0.31) was preventive factor for recurrence of diabetic ketoacidosis.
Conclusion and recommendation: diabetic ketoacidosis leads patients to frequent hospital admission and increases hospital mortality. As a result, health care professionals need to pay more attention to and apply more clinical treatment for patient with type one diabetes mellitus, acute infection, comorbidity, oral type of treatment, and poor medication compliance
Gradient-Guided Swin Transformer with Edge-Aware Fusion for Enhanced Image Super-Resolution
Authors: Qian Chentao , Liu Bailin
Published: October 2024

Existing methods still suffer from undesirable structural distortions.To address this issue, we propose incorporating gradients as high-frequency information to enhance structural preservation. Building on this idea, we introduce the Gradient-Guided Swin Transformer-based (SwinGSR), a novel dual-branch transformer for image SR.Specifically, successive Residual Swin Transformer Blocks (RSTBs) are used to extract deep features from the SR branch (SRB) and gradient branche (GB).SwinGSR leverages high-frequency information to prevent edge structure loss and improve image reconstruction with gradient guidance.Furthermore, we propose a Edge-Aware Fusion Module (EAFM), which incorporates several Channel Shuffle Residual Blocks (CSRBs) as its basic blocks and a Multi-Dconv Head Transposed Attention Block (MDTAB) to integrate features from both branches. This approach addresses the Swin Transformer's limited receptive field and improves feature fusion.The CSRBs enhance generalization by applying channel shuffling.Meanwhile, the MDTAB fully utilizes edge feature information.Extensive experiments demonstrate that SwinGSR outperforms previous methods.
Causal associations between diet and aneurysmal subarachnoid hemorrhage: A Mendelian randomization analysis
Authors: Huang Xinyue , Jiang Xutang , Xiao Yinfeng , Gao Wen , Guo Xiumei , Zheng Hanlin , Pan Zhigang , Zheng Shuni , Ke Chuhan , Hu Weipeng , Ye Lichao , Liu Aihua , Zheng Feng
Published: October 2024

Background
Numerous observational studies have demonstrated that specific dietary factors influence aneurysmal subarachnoid hemorrhage (aSAH). However, whether a causal relationship exists between diet and aSAH remains unknown.
Methods
We used a two-sample Mendelian randomization (MR) method to characterise the causal associations between 26 different diets extracted from the UK Biobank dataset and aSAH risk. The aSAH data were obtained from a meta-analysis of genome-wide association studies from the International Stroke Genetics Union. The inverse variance-weighted method, weighted median, and MR-Egger methods were employed for the MR analyses. A sensitivity analysis was performed to elucidate the heterogeneity and horizontal pleiotropy.
Results
Our results showed that moderate consumption of red wine was associated with a lower risk of aSAH (odds ratio [OR] = 0.136; 95% confidence interval [CI] (0.052–0.353), p < 0.001), with no heterogeneity or horizontal pleiotropy detected. Suggestive correlations were detected between two dietary intakes and aSAH (beef, OR = 6.063, 95% CI (1.203–30.569), p = 0.029; mutton, OR = 4.375, 95% CI (1.273–15.032), p = 0.019). No significant associations were detected between other diets and aSAH.
Conclusions
These findings provide strong genetic evidence for a causal relationship between red wine consumption and aSAH risk. Moderate consumption of red wine was linked to a reduced risk of aSAH. Further larger genome-wide association studies or randomized controlled trials are warranted to confirm these findings.
Childbirth outcomes in women with pregnancy after rape – a comparative study in the Democratic Republic of Congo
Authors: Berg Urban , Mapatano Emile , Hogenäs Maria , Berg Marie
Published: October 2024

Background: The knowledge about childbirth outcomes in women pregnant after rape is limited. This study was conducted in the Democratic Republic of Congo (DRC), a context of war and conflict where sexual violence is frequent. The aim was to compare the childbirth outcomes in women whose pregnancies resulted from rape with outcomes in other pregnant women.
Methods: The study included women being cared for in a new birthing room designed to promote person-centredness, in a tertiary hospital in eastern DRC comparing childbirth outcomes in two groups: women with pregnancy resulting from rape (n=159), and other pregnant women (n=302). Only women classified as Robson group 1 were included, that is, being nulliparous at term with one foetus in cephalic presentation and spontaneous onset of labour. Women pregnant after rape had followed a specific care programme to prepare them for childbirth and motherhood, with continuity of perinatal midwifery care including prenatal education and empowerment. Data included obstetric and neonatal outcomes, and self-reported fear of birth and childbirth experience. The group of women pregnant after rape were younger (16.8 vs 22.5 years), had lower height (151.3 vs 154.9 cm), had a lower level of education, were mostly living without a partner (1.3% vs 96.7%), and had to a lesser extent an accompanying person present during labour (9.4% vs 37.4%).
Results: The childbirth outcomes did not differ significantly between the groups. The proportion of vaginal births was 81.8% vs 83.4% with very few instrumental births, and of caesarean section 18.2% vs 16.6%. Apgar score <7 after 5 minutes was 3.8% vs 1.3%. The self-reported fear of birth was 61% vs 56%, and the overall childbirth experience was mainly scored as good (8–10 on the VAS-OCE scale) (80.5% vs 84.8%).
Conclusions: Childbirth outcomes in women classified as Robson 1 with pregnancy resulting from rape were as favourable as in other pregnant women when being cared for in a more personally adapted birthing room and getting continuous perinatal preparation and support according to a specific care programme.
Effect of Solid State Fermented (SSF) Biomass on In Vitro Methanogenesis and Dry Matter Digestibility in Adult Surti Buffaloes
Authors: Mathukiya Gaurang Pravinbhai , Pandya Paresh R. , Sorathiya Kalpesh K. , Vilas Rathod Sunil
Published: October 2024

An in vitro rumen fermentation study was conducted to evaluate the effect of supplementation with solid state fermented biomass (SSF) in total mixed rations (TMRs) on total gas production, methanogenesis and dry matter digestibility by using the rumen liquor of adult Surti buffaloes. SSF biomass was supplemented at 0, 1, 2, 3, 4, 5, 6, 7, and 8% with TMR (65% wheat straw and 35% concentrate) for in vitro gas production trials. The results of the in vitro study revealed significantly (P < 0.05) greater IVDMD (58.43%) and lower CH4 production (3.58 ml CH4/100 mg DDM) at a 3% level of SSF biomass addition in TMR. Based on the overall results of in vitro studies, 3% SSF biomass supplementation was found to be most suitable for further in vivo studies in adult Surti buffaloes.