bluuebunny/crossref_metadata_2025 huggingface dataset:
Applying Deep Learning with Convolutional Neural Networks to Laryngoscopic Imaging for Real-time Automated Segmentation and Classification of Vocal Cord Leukoplakia
Authors: Hu Juanjuan , Luo Jiawei , Ren Jia , Lan Lan , Zhang Ying , lu dan , Zhou Xiaobo , Yang Hui
Published: August 2021

Objectives The study was to apply deep learning (DL) with convolutional
neural networks (CNNs) to laryngoscopic imaging for assisting in
real-time automated segmentation and classification of vocal cord
leukoplakia. Methods This was a single-center retrospective diagnostic
study included 216 patients who underwent laryngoscope and pathological
examination from October 1, 2018 through October 1, 2019. Lesions were
classified as nonsurgical group (NSG) and surgical group (SG) according
to pathology. All selected images of vocal cord leukoplakia were
annotated independently by 2 expert endoscopists and divided into a
training set, a validation set, and a test set in a ratio of 6:2:2 for
training the model. Results Among the 260 lesions identified in 216
patients, 2220 images from narrow band imaging (NBI) and 2144 images
from white light imaging (WLI) were selected. For segmentation, the
average intersection-over-union (IoU) value exceeded 70%. For
classification, the model was able to classify the surgical group (SG)
by laryngoscope with a sensitivity of 0.93 and specificity of 0.94 in
WLI, and a sensitivity of 0.99 and specificity of 0.97 in NBI. Moreover,
this model achieved a mean average precision (mAP) of 0.81 in WLI and
0.92 in NBI with an IoU> 0.5. Conclusions The study found
that a model developed by applying DL with CNNs to laryngoscopic imaging
results in high sensitivity, specificity, and mAP for automated
segmentation and classification of vocal cord leukoplakia. This finding
shows promise for the application of DL with CNNs in assisting in
accurate diagnosis of vocal cord leukoplakia from WLI and NBI.
Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study
Authors: Slieker Roderick C. , Donnelly Louise A. , Fitipaldi Hugo , Bouland Gerard A. , Giordano Giuseppe N. , Åkerlund Mikael , Gerl Mathias J. , Ahlqvist Emma , Ali Ashfaq , Dragan Iulian , Elders Petra , Festa Andreas , Hansen Michael K. , van der Heijden Amber A. , Mansour Aly Dina , Kim Min , Kuznetsov Dmitry , Mehl Florence , Klose Christian , Simons Kai , Pavo Imre , Pullen Timothy J. , Suvitaival Tommi , Wretlind Asger , Rossing Peter , Lyssenko Valeriya , Legido Quigley Cristina , Groop Leif , Thorens Bernard , Franks Paul W. , Ibberson Mark , Rutter Guy A. , Beulens Joline W.J. , ’t Hart Leen M. , Pearson Ewan R.
Published: August 2021

Type 2 diabetes is a multifactorial disease with multiple underlying aetiologies. To address this heterogeneity, investigators of a previous study clustered people with diabetes according to five diabetes subtypes. The aim of the current study is to investigate the etiology of these clusters by comparing their molecular signatures. In three independent cohorts, in total 15,940 individuals were clustered based on five clinical characteristics. In a subset, genetic (N = 12,828), metabolomic (N = 2,945), lipidomic (N = 2,593), and proteomic (N = 1,170) data were obtained in plasma. For each data type, each cluster was compared with the other four clusters as the reference. The insulin-resistant cluster showed the most distinct molecular signature, with higher branched-chain amino acid, diacylglycerol, and triacylglycerol levels and aberrant protein levels in plasma were enriched for proteins in the intracellular PI3K/Akt pathway. The obese cluster showed higher levels of cytokines. The mild diabetes cluster with high HDL showed the most beneficial molecular profile with effects opposite of those seen in the insulin-resistant cluster. This study shows that clustering people with type 2 diabetes can identify underlying molecular mechanisms related to pancreatic islets, liver, and adipose tissue metabolism. This provides novel biological insights into the diverse aetiological processes that would not be evident when type 2 diabetes is viewed as a homogeneous disease.
H3K4 Trimethylation is Required for Postnatal Pancreatic Endocrine Cell Functional Maturation
Authors: Campbell Stephanie A. , Bégin Jocelyn , McDonald Cassandra L. , Vanderkruk Ben , Stephan Tabea L. , Hoffman Brad G.
Published: August 2021

During pancreas development, endocrine progenitors differentiate
into the islet-cell subtypes, which undergo further functional maturation in
postnatal islet development. In islet b-cells, genes
involved in glucose-stimulated insulin secretion are activated and glucose
exposure increases the insulin response as b-cells mature. Here, we investigated the role of H3K4 trimethylation
in endocrine cell differentiation and functional maturation by disrupting TrxG complex
histone methyltransferase activity in mouse endocrine progenitors. In the
embryo, genetic inactivation of TrxG component Dpy30 in NEUROG3+ cells
did not affect the number of endocrine progenitors or endocrine cell
differentiation. H3K4 trimethylation was progressively lost in postnatal islets
and the mice displayed elevated non-fasting and fasting glycemia, as well as
impaired glucose tolerance by postnatal day 24. Although postnatal endocrine
cell proportions were equivalent to controls, islet RNA-sequencing revealed a
downregulation of genes involved in glucose-stimulated insulin secretion and an
upregulation of immature b-cell
genes. Comparison of histone modification enrichment profiles in NEUROG3+
endocrine progenitors and mature islets suggested that genes downregulated by
loss of H3K4 trimethylation more frequently acquire active histone
modifications during maturation. Taken together, these findings suggest that
H3K4 trimethylation is required for the activation of genes involved in the
functional maturation of pancreatic islet endocrine cells.
Solutions of the differential inequality with a null Lagrangian: higher integrability and removability of singularities. I
Authors: Egorov A.A.
Published: August 2021

The aim of this paper is to derive the self-improving property of integrability for derivatives of solutions of the differential inequality with a null Lagrangian. More precisely, we prove that the solution of the Sobolev class with some Sobolev exponent slightly smaller than the natural one determined by the structural assumption on the involved null Lagrangian actually belongs to the Sobolev class with some Sobolev exponent slightly larger than this natural
exponent. We also apply this property to improve Holder regularity and stability theorems of [19].
Bisphosphonates in Postmenopausal Women with Osteoporosis to Prevent Future Fractures
Authors: I Bashir
Published: August 2021

Postmenopausal women who have osteoporosis are at increased risk of future fractures. Bisphosphonates are drugs that are used to treat osteoporosis by acting on the osteoclasts to inhibit bone resorption. Several studies have shown that bisphosphonate s can maintain or even increase bone mineral density in osteoporosis patients. This review study analyzed the literature on clinical experiments with bisphosphonate therapy in postmenopausal women to determine if these drugs are efficacious in preventing f uture fractures. Four out of five studies found that women treated with bisphosphonates were at decreased risk of future fractures, and six of six studies found that bisphosphonate therapy increases bone mineral density relative to placebo control. Althoug h further work is warranted to understand the level of bone mineral density increase that is associated with fracture prevention, this study implies that bisphosphonate therapy can be used to help prevent future fractures in postmenopausal osteoporotic wom en. The study is significant in that it helps to underscore the efficacy of bisphosphonate therapy in postmenopausal women, and it may be generalizable to other populations with osteopo s rosis who are at increased risk of fractures.
Slipped Capital Femoral Epiphysis (SCFE) Coxa Vara Adolescentium (CVA)
Authors: A Gharaibeh
Published: August 2021

Slipped fem oral capital epiphysis is considered to be one of the most destructive conditions of hip joint during adolescence. The epiphysolysis of the femoral head was first defined in 1572 by the French surgeon Abrois Paré (1510 - 1590). The first authentic traumati c epiphysesolysis of the femoral head was described by Brousseau in 1867. It was in a 15 - year - old boy with multiple injuries after trauma with heavy carriage. Death occurred in a few hours, and was discovered by post - mortem examination. Complete separation of epiphysis of the femur head was found. The first mention of a non - traumatic form of epiphysolysis occurred in a fourteen years old boy later. In 1881, Fiorani reported fifteen cases of distorted hip joint with impaired adduction in children. He describ ed the deformity as a bend of the proximal part of the femur, which was based on rickets. With a high probability, some individua ls were coxa vara adolescentium . The first complete description of the disease was given by E Müller (1888) in his work “ About the bending of the femoral neck in the growth age ” Coxa vara adolescentium (CVA), epiphysesolysis of femural head or slipped femoral capital epiphysis represents a serious hip disease in the pubescent age at which the femoral proximal growth plate loses it s strength and influence mechanical forces, caused mainly by excessive body weight, the non - traumatic epiphysesolysis will occur. Symptoms like pain and twisting are initially vague, but they tend to escalate over time . The incidence of this disease is 0. 1 per one million, affect male more than female 2:1,4 in the rapid growth period 10 - 16 years old. Childhood obesity is the common cause of Slipped femoral capital epiphysis, then endocrine disorders and Down syndrome. Slipped femoral capital epiphysis has three grades first up to 33 degrees of slippage, second grade from 34 - 50% of slippage and the third degree more than 50%.Slipped femoral capital epiphysis, represents a serious disease of the puberty in the pubescent age at which the femoral proximal growth plate loses its strength and influence mechanical forces, caused mainly by excessive body weight, will occu r non - traumatic epiphysesolysis . Symptoms like pain and limping are initially vague, but they tend to escalate over time .
Study on Bovine Trypanosomosis and Tse Tse Fly Challenge in Darimu District of Birbir Valley, South Western Ethiopia
Authors: Benti Teferi
Published: August 2021

This study was undertaken on bovine trypanosomia sis and its vectors at Birbir valley located in Darmu district, Illubababor zone. The parasitological examination was conducted using Buffy coat technique while vector survey was conducted using odour baited Monopyramidal trap. The objective of the study w as to determine the prevalence of trypanosomiasis in cattle, to determine fly density and to identify associated risk factors. From 392 Blood samples were collected, 45(11.5%) were found to be positive by Buffy coat technique and trypanosome species identi fied by their motility were T.congolense 40 (88.9%) and T.vivax 5(11.1 %) and Trypanosoma congolense was the dominant species. A total of 52 Monopyramidal traps were deployed and 1836 (73%) tsetse flies and 676(26.9%) biting flies were caught. From flies c aptured, 971(52.9%), 540(29.4%) and 325(17.7%) Glossina morsitans sub morsitans of savannah flies, Glossina fuscipes fuscipes of reverine and Glossina pallidipes of savannah species were identified respectively. The overall apparent densities fly / trap / day (FTD) were 17.7 and 6.5 for tsetse and biting flies respectively. There was no statically significant difference (P > 0.05) in the prevalence of trypanosome infection between sex group while statistically significant difference was observed between age group(x 2 =41.0, p=0.000 , p<0.05). The mean PCV of the parasitemic and aparasitemic animals were 21.3% and 24.3% respectively .The difference between the mean PCV value of the parasitemic and apparasitemic animals were statistically significant(P< 0.05). Designing and implementation of trypanosomosis control should be targeted to the major cyclically transmitting tsetse flies.
Rare Case Report on Emamect in Benzoate Poisoning in Buffaloes
Authors: S Sivajothi
Published: August 2021

Emamectin benzoate is a macrocyclic lactone which is commonly used as pest control in agriculture and indiscriminate use of these compounds causes toxicity in the livestock. Two buffaloes were reported to be had a history of acc idental ingestion of emamectin benzoate mixed solution and they showed disorientation, circling, incoordination, salivation, nasal discharges and shivering. Animals were treated with atropine sulfate, fluid therapy with vitamin supplementation and oral lax atives. Adult buffalo was recovered from the toxicity by the fifth day of therapy but buffalo calf was died by the second day of therapy.
Management of Dystocia due to Schistosoma reflexus in a Cross - Bred Cow
Authors: SK Sheetal
Published: August 2021

Schistosoma reflexus is a rare type of foetal monster which causes dystocia in cow. It was managed by caesarean - section to save the life of the dam and the cow recovered uneventfully following post operative therapy.
Abattoir Prevalence of Bovine Cysticercosis in Cattle Slaughtered at Haramaya Municipal Abattoir, Eastern Hararghe Zone Of Oromia Region
Authors: M Ahmed Adem
Published: August 2021

A cross - sectional study was conducted from November, 2011 to April, 2012 on bovine cysticercosis in cattle slaughtered at Haramaya Municipal Abattoir with the objectives of determining the prevalence of bovine cysticercosis and to characterize the viabilit y of the cyst. Out of 384 systematically selected slaughtered cattle, 28 (7.27%) were infected with Cysticercusbovis. A total of 126 cysts were collected in which 76 (60.32%) were viable while others 50 (39.68%) were degenerated. The anatomical distributio n of cysticerci was liver, heart, shoulder muscle, tongue, masseter and lung in decreasing order of cyst harboring. A statistical analysis of infection rate on the basis of origin of the animal and sex has no significant difference (p> 0.05) but age has si gnificant difference (p<0.05). In conclusion, the present study imply that the disease deserves due attention to safeguard the public health and promote beef industry in the country. Therefore, appropriate control and preventive measures should be taken in order to reduce the disease problem on public health even if its economic significance associated with cysticercosis is minimal.
Incidence and Associated Risk Actors of Heifer Mastitis in Dairy Farms at Mekelle Town, Northern Ethiopia
Authors: M Bisrat
Published: August 2021

A longitudinal study was conducted from November 2013 to May 2014 in Mekelle town, Northern Ethiopia, to assess the incidence of heifer mastitis, to isolate and identify the causative pathogens and their susceptibility to different antimicrobials and also identify risk factors associated with occurrence of heifer mastitis. Twenty - five heifers were included from 4 d airy farms and 11 cooperative small holder’s dairy farms during the study period. Total of 100 quarters were examined to detect clinical and subclinical mastitis by physical examinations of udder and milk and California mastitis Test (CMT), respectively. T he incidence of mastitis per gland at risk was 64 % and the spontaneous cure rate of infected quarters was 33 %. Incidence of heifers’ intra - mammary infections (IMI) in the study area was highest at calving (28%). Infection per quarter revealed that 49% we re mastitis positive of which 8.2% of their quarters were clinical and 45/49 (91.8%) quarters were sub clinical type of mastitis. The incidence rate per quarters were statistically significant (p <0.05) and higher in rear quarters than front quarters. The univariate logistic regression showed that among potential risk factors considered from the farm attributes, breed, age, practice of milking mastitic cow last, housing nature, hand wash before and in between milking and udder hygiene had significant effect on the prevalence of subclinical mastitis. Coagulase negative Staphylococci (CNS) (54.5%) and Staphylococcus aureus (21.8%) , were the predominant bacteria. Relatively most of the isolates are susceptible to Chloramphenicol, Gentamycin, Ciprofloxacin and V ancomycin but resistant to Penicillin. The study also revealed that S.aureus, E.coli and S.agalactiae were highly incident at calving. It is concluded that prevalence of CNS, lack of hygienic practice and infestation of ticks should give serious attention.Intramammary treatment of prepartum heifer with appropriate antimicrobials may help to reduce the incidence of mastitis at calving and subsequent lactation period.
A Rapid and Effective Method to Prolong Pain Relief in Sheep Using Bupivacaine and Intralipid ® Combination
Authors: Sahebjam Farzin
Published: August 2021

Background : To compare the duration of action of a local anesthetic block using a lipid formulation of bupivacaine to the commercially available aqueous formulation. Bupivacaine 0.5% was mixed with an equal volume of either lipid emulsion (Intralipid, Fresenius Kabi) or normal saline resulting in a final concentration of 0.25% bupivacaine. Eighteen sheep were administered a n erve block of either control or treatment at the metacarpal region of each forelimb to compare the efficacy of the injected formulations. The nociceptive test was determined by applying a blunt noxious stimulus to the foot below the nerve block at multiple time intervals until the sheep responded by withdrawing its foot. The person assessing the response to the noxious stimulus was blinded to the treatment. Results: The Intralipid formulation significantly extended the duration of the nerve block compared to the control group. The mean analgesic period (mean±SD) in the control legs was 4.23±1.8 hr. compared to 5.81±1.78 hr. in the Intralipid injected legs (p=0.013). Conclusions : In conclusion, an Intralipid® - based formulation provided a more prolonged dura tion of local anesthesia after nerve blocks in the sheep metacarpal region compared to aqueous bupivacaine.
One-Dimensional Hydrogen-Bonded N–H…O in the Hybrid Phosphate: Hirshfeld Surface Analysis and DFT Quantum Chemical Calculations
Authors:   Laboratory of Materials, Electrochemistry and Environment Faculty of Sciences, Chemistry Department, Ibn Tofail University, Kenitra city, Morocco, Rafik Abdellatif , Zouihri Hafid ,   Laboratory of Materials Chemistry and Biotechnology of Natural Products, Moulay Ismail University, Meknes, Morocco, Guedira Taoufiq ,   Laboratory of Materials, Electrochemistry and Environment Faculty of Sciences, Chemistry Department, Ibn Tofail University, Kenitra city, Morocco
Published: August 2021

In the present work the 3D-supramolecular network is stabilized by N–H…O and O–H…O hydrogen bonds, by O…N interactions involving the organic cation and inorganic anion as checked by Hirshfeld surface analysis. The van der Waals contacts play a key role in the consolidation of the packing of 4-chloro-2-methylanilinium dihydrogenphosphate[4-CMDHP] structure. In order to support experimental results, density functional theory calculations have been performed using B3LYP functional with 3-21 G basis set. All of the obtained theoretical results are in a perfect agreement with the experimental ones. Furthermore, nonlinear optical behavior of 4-CMDHP has been investigated by determining the Hirshfeld surface, density of states and HOMO-LUMO energy gap using the same basis set. Finally, the molecular electrostatic potential surface of 4-CMDHP molecule was simulated and discussed.
Synthesis, Characterization and Application of a Diatomite-Based Composite for the Adsorption of Anionic Dyes in Aqueous Solutions
Authors:   Laboratory of Materials, Applications and Environment, Mustapha Stambouli University, P.B. 305 Mamounia road, Mascara 29000, Algeria, Chentouf Sadek , Kacha Smail ,   Laboratory of Advanced Materials and Physicochemistry for the Environment and Health (MAPES), Djillali Liabes University, P.B. 89 Sidi Bel Abbes 22000, Algeria, Marouf Réda ,   Laboratory of Materials, Applications and Environment, Mustapha Stambouli University, P.B. 305 Mamounia road, Mascara 29000, Algeria, Benhafsa Fouad Mekhalef ,   Laboratory of Advanced Materials and Physicochemistry for the Environment and Health (MAPES), Djillali Liabes University, P.B. 89 Sidi Bel Abbes 22000, Algeria,   Scientific and Technical Research Center on Physical and Chemical Analyses (CRAPC), Industrial Zone Bou-Ismail, Tipaza, Algeria, Leboukh Abdelkader ,   Laboratory of Advanced Materials and Physicochemistry for the Environment and Health (MAPES), Djillali Liabes University, P.B. 89 Sidi Bel Abbes 22000, Algeria, Yahiaoui Ahmed ,   Laboratory of Organic Chemistry, Macromolecular and Materials, Mustapha Stambouli University, P.B. 305 Mamounia road, Mascara 29000, Algeria
Published: August 2021

Synthesis, characterization and application of the polyaniline-diatomite (PAD) composite in the adsorption of Reactive Red 120 (RR 120) and Acid Blue (AB) dyes were carried out. The composite was prepared by the in situ polymerization of aniline. Mass of purified diatomite was mixed with a solution containing aniline dissolved in 2M hydrochloric acid at room temperature. The solid obtained was characterized using the SEM, XRD and FTIR analyses. The kinetic adsorption of dyes was described using the pseudo-second order kinetic model. The adsorption isotherm of the RR 120 dye can be fitted by the Freundlich adsorption isotherm model. However, the adsorption isotherm of the AB dye can be better fitted by the BET model.
Compositional Fibers Based on Coal Tar Mesophase Pitch Obtained by Electrospinning Method
Authors:   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan, Imangazy Aldan , Smagulova Gaukhar ,   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan,   Institute of Combustion Problems, 172 Bogenbaybatyr St., Almaty 050012, Republic of Kazakhstan, Kaidar Bayan ,   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan,   Institute of Combustion Problems, 172 Bogenbaybatyr St., Almaty 050012, Republic of Kazakhstan, Mansurov Zulkhair ,   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan,   Institute of Combustion Problems, 172 Bogenbaybatyr St., Almaty 050012, Republic of Kazakhstan, Kerimkulova Almagul ,   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan,   Institute of Combustion Problems, 172 Bogenbaybatyr St., Almaty 050012, Republic of Kazakhstan, Umbetkaliev Kuanysh ,   Kazakh National University named after al-Farabi, 71 al-Farabi Ave., Almaty 050040, Republic of Kazakhstan, Zakhidov Anvar ,   University of Texas at Dallas, 800 W. Campbell Road, Richardson 75080-3021, Texas, USA, Vorobyev Pavel ,   Bekturov Institute of Chemical Sciences, 106 Sh. Ualikhanov St., Almaty 050010, Republic of Kazakhstan, Jumadilov Talkybek ,   Bekturov Institute of Chemical Sciences, 106 Sh. Ualikhanov St., Almaty 050010, Republic of Kazakhstan
Published: August 2021

This research examines the use of coal-processing wastes of Shubarkol deposit (Kazakhstan) in obtaining useful materials such as carbon fibers. For our experiments, mesophase pitch was obtained by coal tar heat treatment at 773 K. Spinnable solution was prepared by crushing mesophase pitch into the pieces with adding poly(methylmethacrylate) as a fiber-forming material and 1,2-dichloroethane as a solvent. Elemental analysis revealed that the chemical composition of mesophase pitch (С – 91.48 %; О – 8.52 %; S – 0.00 %) showed that heat treatment up to 773 K leads to the complete removal of sulfur-containing components which affect the mesophase formation. Raman data of the obtained pitch revealed the appearance of D (1366 cm-1) and G (1605 cm-1) peaks, which are responsible for carbon materials; another peak at 2900 cm-1 shows the presence of C–H bonds. Carbon fibers with the diameter of 0.8–1.75 μm were obtained by electrospinning method in laboratory settings.
Study on the Properties of Semi-Synthetic Motor Oil Castrol 10W-40 after Use in a Diesel Engine
Authors:   Lviv Polytechnic National University 12 S. Bandery str., 79013 Lviv, Ukraine, Chervinskyy Taras , Grynyshyn Oleg ,   Lviv Polytechnic National University 12, S. Bandery St., 79013 Lviv, Ukraine, Prokop Roman ,   Lviv Polytechnic National University 12, S. Bandery St., 79013 Lviv, Ukraine, Shapoval Pavlo ,   Lviv Polytechnic National University 12, S. Bandery St., 79013 Lviv, Ukraine, Korchak Bohdan ,   Lviv Polytechnic National University, 12, Bandera St., 79013 Lviv, Ukraine
Published: August 2021

The changes in operational and physico-chemical properties of original and used semi-synthetic motor oil Castrol 10W-40 before and after its use in a diesel engine have been investigated. Derivatographic studies were carried out to examine a thermal stability; IR spectroscopy was used to confirm the presence of oil aging products. The composition of the inorganic part of the studied semi-synthetic oils was established by X-ray fluorescence analysis.
«Intrecci di fiori e di allori» Dialoghi italo-tedeschi su letteratura e linguistica. Una nascita controversa
Authors: Sangiovanni Fabio
Published: August 2021

In 1983, Wilhelm Pötters introduced to the Italian attention a new theory on the genesis of the sonnet based on the relationship between mathematics and metrics, integrating the problem of ‘derivation’ with that of ‘invention’: it was the beginning of a heated debate, initiated by a single research project in Germany and welcomed in Italy by touchy refusals or enthusiastic acceptance, of which this contribution gives an overall interpretation.
Analisis Kebijakan Ekonomi dan Kesejahteraan Sosial Perspektif Maqāṣid Asy-Syarīʻah (Studi Pasal 88 UU Nomor 11 Tahun 2020)
Authors: Hidayat Ma'ruf
Published: August 2021

The coverage of the draft Law on Job Creation has drawn polemics from a number of parties, one of which is from workers who have taken action against regulations related to labor clusters which have changed many articles in Law Number 13 of 2003 concerning Manpower. This paper examines the implications of the Work Creation Omnibus Law Bill from the perspective of maqasid sharia which focuses on labor issues. This type of research is included in qualitative research in the form of descriptive, which explains some of the articles of the Omnibus law Cipta Kerja. The method used to obtain data is a normative juridical approach in the form of primary legal material, namely Law no. 11 of 2020 concerning Job Creation. Then for the collection and data analysis methods using descriptive analytical. The results of the study show that the concept of welfare in the omnibus law refers to the labor law where every worker has the right to earn income that meets a decent living, this is self-intersest and material oriented, while in the concept of Maqāṣid asy-syarīʻah is an orientation to maslahah which covers all aspects. human life which includes protection of religion, soul, descent, wealth, reason.
The methodology for creating an information and analytical system for control, planning and management of the educational process in HEIS and its functional structure
Authors: Kolodii Ihor , Byelova Lyudmyla , Aleikseieiva Svitlana , Kushnir Vadym , Rudyk Yaroslav , Kalichak Yurii
Published: August 2021

The aim of the study is to establish the level of efficiency and feasibility of automated information and analytical management system, as well as to identify ways to organize cooperation between individual departments of the university and consider the level of IAS components evaluation by teachers in the educational process, which are key elements of the transition to a digital management model of HEIs. The hypothesis is that information technologies of educational process management increase the involvement of participants in the educational sector in the model of university administration, increase the efficiency of planning and ensure the objectivity of the control system. The result of the study is to establish that the information and analytical system of education process management in the university is user-friendly, positively perceived by students, and contributes to the simplicity and efficiency of assessment in HEIs.
Creative competence in the educational activity of a day-to-day teacher
Authors: Novakivska Lyudmyla , Bialyk Oksana , Zadorozhna Оlena , Nypadymka Alla , Kashubiak Iryna , Kravchenko Anatoly
Published: August 2021

The article is devoted to the actual problem of the teacher's professionalism, namely, creative competence, which is understood as the ability to create new professional products and high performance results through the implementation of the creative abilities of the individual. The approaches to pedagogical activity as a creative process are analyzed. It is noted that the question of the structure and qualitative characteristics of the teacher's creative competence as a system of changes is still debatable.
Vocal ensemble: organization and functioning in the musical and educational environment
Authors: Savchenko-Shlapak Yuliia , Savchenko Regina , Qianyi Pan
Published: August 2021

The article deals with the problem of the organization and functioning of a vocal ensemble as a means of developing the performing skills of students of higher educational institutions of a musical and pedagogical profile.  The criteria for the quality of training a future specialist for the effective implementation of his practical activities as a leader of a children's and youth vocal group are indicated. The purpose of the article is a theoretical substantiation of the content of work on the organization and functioning of the vocal ensemble of students as a way of developing their performing skills. Organization of a vocal ensemble is leadership and work on the functioning of a vocal ensemble as a creative team, the realization of its needs. Being an organized social group, the ensemble has a number of features, which include: creative self-development and the desire for creative interaction; increased self-organization and focus.
The Potential of Vā Part 4: Methodology of Lala- Vā
Authors: Simati-Kumar Benita
Published: August 2021

The article presented is part of a series of chapters that composed an exegesis, submitted in fulfilment of the requirements for the degree of Doctor of Philosophy. The series is a narrative of discovery through practice-led research. Each article reveals its purpose and significance that leads into the next series, which then eventuate to that final design proposal.

The exegesis is presented in this format, to break down the components that assisted in practice-led research. Each article can be read and unpacked on its own as a learning tool. The purpose of this edited series is for the exegesis to be more accessible and adaptable creatively to those being introduced to practice-led research.

The Potential of Vā Part 4: Methodology of Lala- Vā, presents the methodology of Lala-Vā to approach the research design. Archival research, current museum displays, participation and documentation, and experimentation are the sections that are explored within this methodology. Lalava and lalaga- the two different kinds of traditional practice used to address the research question- are outlined here as well as the strengths and weaknesses of these approaches.
Fuerza de Carácter y Continuidad Emprendedora: Evidencia de Ecuador
Authors: Noboa Fabrizio
Published: August 2021

El objetivo del presente estudio es analizar si la fuerza de carácter, la tendencia de una persona a mostrar perseverancia en el esfuerzo, constancia en el interés y pasión en objetivos de largo plazo, influye en la continuidad emprendedora en Ecuador. Empleando una prueba chi-cuadrado, compara el nivel de fuerza de carácter de dos grupos de emprendedores, uno con iniciativas empresariales avanzadas y otro con iniciativas menos maduras, y demuestra que los emprendedores que tienen mayor fuerza de carácter, según evaluación de terceros, construyen empresas con mayor capacidad de seguir operando. Este hallazgo sugiere que, pese a competir en ecosistemas con limitaciones, personas con fuerza de carácter son capaces de superar obstáculos externos y consiguen que su iniciativa empresarial avance.
Effect of Video-assisted Teaching on Knowledge of Staff Nurses regarding Lamaze Breathing Exercises during the First Stage of Labour to Improve Maternal and Foetal Outcome among Primi Parturient Mothers
Authors:   RKDF College of Nursing, Bhopal, Madhya Pradesh, India, Nagvanshi Sharda
Published: August 2021

Background: The present study was conducted to assess the impact of video aided teaching on knowledge gain of staff nurses regarding lamaze breathing exercises throughout the first stage of labour. Method: An experimental research design was chosen with pre-test and post-test of experimental and control group. The sample size was sixty registered staff nurses divided into two groups, thirty in experimental and thirty in control group. The tools used for conducting the study included demographic data and a self structured questionnaire to assess knowledge of experimental and control group. The experimental group was given video assisted teaching as an intervention and the control group was used for comparison without intervention. Result: The data were analysed with the help of descriptive and inferential statistics. The study clearly shows that there was a significant gain in knowledge of staff nurses of the experimental group with video assisted teaching that emphasises the lamaze breathing exercises during first stage of labour are safe measures to enhance maternal and foetal outcomes. Conclusion: The staff nurses are benefited with video assisted teaching to enhance knowledge and they can use the breathing exercises during first stage of labour to promote comfort to labouring women and also minimise the use of medication and risk of LSCS during labour.
Our Potential and Challenges of Social Media in Promoting Women’s Health
Authors:   Post Doctoral Fellow, ICSSR, Pandey Neelesh
Published: August 2021

Women’s health is a matter of concern for very countries. The advancement in the field of internet and emergence of social media has affected communication process to a great extent. As social media has advantage over traditional media because of web based applications, it can be used to promote health communication especially women’s health which is neglected over the time. The present article attempts to find out the potential and challenges of social media for using as a tool to promote and aware the public on women’s health.
Tik Tok the New Alternative Media for Youngsters for Online Sharing of Talent: An Analytical Study
Authors:   Researcher (Academic), MGCGU, Chitrakoot, Madhya Pradesh, India, Patel Keshav
Published: August 2021

Tik Tok, the new wave of social media which has introduced a new sub culture for the present generation and has brought a revolution in the social media for youngsters. Tik Tok has become a new platform for portrayal of talent for youngsters adding new meaning to already existing social media platforms. It is the fastest growing social media which has fascinated and engrossed so many youngsters across the globe and is one of the fastest growing in India. Tik Tok is basically the new alternative version of online sharing, that allows its users its interface for preparing short videos and music pieces. Tik Tok is the new obsession among youngsters which is giving them a platform to express them innovatively and ingeniously. The present paper is based on case study of individuals who used Tik Tok to highlight their talent.
The Theme of Love in Sarojini Naidu’s Poetry
Authors:   Faculty in English, Shershah College of Engg. Sasaram, Bihar, Chouhan Sandhya
Published: August 2021

Love is the dominant theme of Sarojini Naidu’s poetry. There are a large number of love-lyrics in the store of her poetry. As a love-lyricist, Sarojini Naodu is superb. Her lyrics deal with human love to metaphysical love. Thus, her love-lyrics have an aesthetic approbation of contemplation and sensation.
THE RELATIONSHIP BETWEEN THE NUMBER OF TOURISTS ARRIVED IN ROMANIA'S DEVELOPMENT REGIONS AND THE GROSS DOMESTIC PRODUCT
Authors: Cosmin Nicolae Mirea , Alexandra Maria Sârbu , Andra Maria Ionescu
Published: August 2021

At national level, the contribution of tourism to the formation of the Gross Domestic Product is quite significant, considering the year 2019, when the contribution of tourism was 6.1% (World Travel & Tourism Council, 2021). Thus, the connection between tourism and Gross Domestic Product is indisputable. The purpose of this study is to
find out the influence of the number of tourists arriving in the development regions of Romania on the Gross Domestic Product. The regression method was applied for data processing, using the statistical program EViews. The highest increase in the Gross Domestic Product, depending on the increase in the number of tourists, is registered in the South-Muntenia Development Region, and the smallest increase is registered in the Bucharest-Ilfov Development Region. The results show that a large number of tourists does not necessarily mean generating a considerable increase in Gross Domestic Product.
A RETROSPECTIVE LOOK AT THE EVOLUTION OF ROMANIAN TOURISM, AT THE BORDER BETWEEN THE MILLENNIA (1989-2019)
Authors: Puiu Nistoreanu , Mihail – Ovidiu Tănase
Published: August 2021

During the last 30 years we have witnessed major changes in tourism worldwide due to a lot of factors. Changes in political situation in Eastern Europe open a lot of countries to international tourism. Changes in air transport made more accessible some overseas or island destination. The increase of general welfare boosted the demand
for tourism and the stability of the socio-political environment sustains a steady upward trend in international tourism arrivals. Looking back at Romania’s tourism we see a period with major structural changes and some major turning points. A brief evolution of the sector is presented with an emphasis on the most important years.
The most important regulations are presented in this paper together with their impact on Romania’s tourism sector. To show a more accurate image we include main statistical information about this topic demonstrating that tourism is an important part of Romanian economy.
Проблема формирования и диагностики функциональной грамотности российских школьников: мотивационный фокус
Authors: Махова И. Ю.
Published: August 2021

Проанализировано понятие функциональной грамотности учащихся как результат общего образования в контексте его оценки в рамках международного сопоставительного исследования PISA. Показано, что научно-педагогические попытки улучшить результаты 15-летних российских учащихся на протяжении 20 лет мониторинга PISA не успешны наряду с устойчиво высокими результатами младших школьников России в сопоставительном международном исследовании PIRLS. Функциональная грамотность связана с актуальной адаптацией к различным жизненным ситуациям, актуальным использованием знаний учащимися различных предметных сфер и метапредметных знаний, сопоставима с целевыми установками обучения в основной школе России на компетентное поведение. Мотивация рассматривается на основе анализа работ как фактор компетентного поведения. Обозначены условия порождения внутренних мотивов, которые нереализуемы в рамках отечественной образовательной парадигмы, ориентированной на предметоцентризм: возможность влиять на предстоящие события, сопряженность действия и результата, контроль ситуации, специфика контроля действий, мера реальности представляемого содержания, условия возникновения и характер цели действия. Осуществлена проверка гипотезы о влиянии внешних мотивов учебного поведения 15-летних школьников на результаты выполнения тестовых заданий в формате PISA. Приведены результаты измерения функциональной грамотности учащихся 9 классов математического лицея № 1 г. Комсомольска-на-Амуре, являющегося базовой школой РАН, а также анкетирования, направленного на оценку отношения учащихся к заданиям формата PISA. Сделан вывод о внешних учебных мотивах лицеистов. Обнаруженные в ходе исследования факты демонстрируют объяснительные возможности и прогностический потенциал мотивационного фокуса проблемы неуспеха российских школьников в международных сопоставительных исследованиях PISA, системный характер низкого уровня функциональной грамотности.
Air Pollution with Asbestos Fibers in Some Heavy Traffic Areas of Baghdad
Authors: Ajeel Nahla Sh. , Fleeh Nada A. , Sultan Matham A.
Published: August 2021

This research was conducted to measure the levels of asbestos fibers in the air of some dense sites of Baghdad city, which were monitored in autumn 2019. Samples collection was conducted via directing air flow to a mixed cellulose ester membrane filter mounted on an open‑faced filter holder using sniffer with a low flow sampling pump. Air samples were collected from four studied areas selected in some high traffic areas of Baghdad city, two of them were located in Karkh (Al-Bayaa and Al-Shurta tunnel) and two in Rusafa (Al-Jadriya and Al-Meshin complex), then analyzed to determine concentrations of asbestos. Measuring of levels of asbestos fibers on the filters was carried out via using scanning electron microscope SEM together with  an energy dispersive X‑ray system (EDS). The results showed that the lowest level was recorded in Al-Jadriya intersection (0.0352 fiber/ml), while the maximum concentration was in Al-Bayaa (0.156 f/ml). Asbestos average concentration in the ambient air of the four studied areas was 0.0718 f/ml, which exceeded the standards of world health organization (WHO) for air which is equal to 0.0022 f/ml. This may be due to the presence of crowded traffic and the occurrence of industries near the city. Therefore, plans such as management of traffic, changing locations of industrial sites, and products substitution can be effective in minimizing the concentrations of airborne fibers.
Antagonistic Activity of Bacteriocin-producing Lactobacillus Against Candida spp
Authors: Mohsin Zainab Abdulridha , Ali Wala’a Shawkat
Published: August 2021

In order to screen antifungal activity of lactobacilli that produce bacteriocin against the yeast Candida, ninety-two food and clinical samples were collected. Also, several commercial brands of Lactobacillus probiotics and ready-made isolates of Lactobacillus were used. The isolated lactobacilli were subjected to microscopic, macroscopic, and biochemical tests. Moreover, molecular identification was performed for the best producer isolate. For Candida spp. isolation, seventy- two samples were collected from different clinical sources; in addition, nine of ready-made isolates were also used. All the isolated Candida spp. were subjected to microscopic and macroscopic examinations which were confirmed by VITEK® 2 YST card automated system. Detection of bacteriocin production from Lactobacillus was investigated by primary and secondary screening techniques and the results showed that the agar wells diffusion method was the best. The most efficient isolate to produce bacteriocin was L. plantarum WZD3, in which antifungal activity of bacteriocin was at the level of 80 and 40 AU/ml against the most sensitive Candida isolates; C. albicans CA and C. albicans CB, respectively. After partial purification of bacteriocin by n-butanol extraction method, bacteriocin activity was increased to 320 AU/ml against both yeast isolates. In conclusion, L. plantarum WZD3 or its bacteriocin could be a good candidate as antifungal agent to treat Candida infections and more studies are required to evaluate its acivity against other types of medical fungi.
Estrategias de marketing en tiempos de Covid-19 en Empresas del sureste mexicano
Authors: Zetina Pérez Carlos David , Juárez Solís Sandra , Alvarado García Leidy Cristhel
Published: August 2021

Los cambios constantes en el entorno son un fuerte reto que hace necesaria la toma de decisiones y en este año de 2020 sin duda alguna la situación de la pandemia COVID-19 afectó a todos los sectores en un evento histórico que pone en riesgo el funcionamiento de un gran número de empresas en el mundo, de manera importante el marketing estratégico brinda la dirección para enfrentar los cambios y ayuda a conocer las estrategias enfocadas desde el Marketing Mix. El estudio llevó a cabo 26 entrevistas con empresarios de zonas urbanas y rurales in Situ, además se aplicó un cuestionario tipo Likert a 38 empresas, todo esto con la finalidad de hacer una descripción de la afectación y de las principales estrategias concluyendo que determinados tipos de negocio y en zonas rurales el impacto fue menor, siendo la plaza la estrategia del Marketing Mix más socorrida.
Mercados diferenciados en organizaciones cafetaleras del centro de Veracruz, México
Authors: Ramos Rivera Liliana , Nava Tablada Martha Elena , Escamilla Prado Esteban
Published: August 2021

México está entre los diez principales productores de café y Veracruz ocupa el segundo lugar nacional. Desde fines del siglo XX hay una crisis derivada de la liberación del mercado internacional, sobreproducción y bajos precios. En México se traduce en políticas de privatización que repercuten negativamente en las regiones cafetaleras. Algunos cafeticultores han podido mantenerse incursionando en mercados diferenciados que otorgan un sobreprecio al producto. El objetivo fue identificar los problemas y retos que enfrentan ocho organizaciones para comercializar café en mercados diferenciados. Se aplicó una entrevista semiestructurada a los dirigentes y los datos se analizaron cualitativamente. Los principales problemas son: reducidos nichos en mercados de especialidad, deficiente mercadotecnia, altos costos de exportación y bajo consumo nacional. Los retos: incrementar la productividad y calidad, mejorar estrategias de mercadotecnia y fomentar el consumo nacional. Los mercados diferenciados presentan alto potencial ante la crisis, si son parte de una estrategia integral.
Tu no, pero tú sí. Y cómo el sector gastronómico incrementó sus ventas durante la emergencia sanitaria por la COVID-19 en la Ciudad de Xalapa, Veracruz.
Authors: Vázquez Otero Roberto
Published: August 2021

Ante la contingencia sanitaria por el brote de COVID-19 en el mundo, en la Ciudad de Xalapa, Veracruz, las acciones para cuidar a todos incluyeron el cierre de empresas del sector gastronómico dejando el servicio sólo para llevar. Este gran reto es también una oportunidad para el sector, que a diario crece en ofertantes y demandantes. Cada restaurante, deberá analizar sus proyectos financieros y su plan de negocios con la finalidad de dar el mejor servicio al comensal y mantenerse en el tiempo. Sirva este documento de reflexión para analizar sobre la importancia de las finanzas en las empresas del sector gastronómico y el quehacer de su gerente comercial.
Cultural positioning and strategic resilience
Authors: Schembri Sharon
Published: August 2021

The international corridor located on the US-Mexico border is recognized as a highly resilient community existing within the fast-emerging economy. This community comprises a cultural integration of American and Latinx cultures, which is evident within business and consumer practices. Accordingly, business and branding strategy is culturally oriented and culturally expressive. This paper presents two business cases that illustrate how cultural positioning is achieved with local brands that expand beyond the local context to the mainstream market. The two cases presented in this paper are Topo Chico and Laredo Taco. Each of these cases began within a cultural niche with recognized potential that translated to the mainstream American market, demonstrating strategic resilience along the way. The Topo Chico case shows perseverance in a bottle and the Laredo Taco case shows resilience combined as authenticity and innovation. The implications of the cases presented to demonstrate the value of a strong cultural positioning, strategic alliances, and a view to the longer term and farther horizon.