bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic variability of ANG2-35G>C gene as a predictor factor in sepsis
Authors: Szederjesi Janos , Lazar Alexandra , Petrisor Marius , Hutanu Adina , Tripon Florin , Georgescu Anca Meda , Azamfirei Leonard
Published: May 2020

To date it is unknown if there is a predisposition to sepsis. In this respect, genetic studies have been conducted with the aim to find gene variants which can point out a higher predisposition to developing sepsis. The primary objective of this study is to highlight whether the genetic polymorphism of Angiopoietin-2 gene (ANG2-35G>C) is present mainly in septic patients. As secondary objectives we aimed to evaluate if there are any associations between ANG2-35G>C polymorphism and the severity scores Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiology Score (SAPS) as well as routine tests in septic patients such as C reactive protein (CRP), procalcitonin (PCT). We enrolled adult patients admitted to the Intensive Care Unit (ICU). After admission to the ICU and the diagnosis of sepsis, blood samples were collected and the severity scores: APACHE II, SAPS were calculated on the first day of ICU admission. We recorded the following from the blood samples: CRP, PCT, angiopoietine2 (Ang-2). We performed several one-way ANOVA tests to determine any significant mean difference of the analyzed variables. We observed that variant genotypes of ANG2-35G>C gene polymorphism are significantly related to CRP, aspect which increases this biomarker credibility compared with others (i.e., PCT), in septic patients. ANG2-35G>C gene polymorphism is associated with severity scores, APACHE II, and SAPS in sepsis.
Advancements in Thermal Energy Storage System by Applications of Nanofluid Based Solar Collector: A Review
Authors: Kalbande Vednath P. , Walke Pramod V. , Kriplani C. V. M.
Published: May 2020

In the recent years, a lot of research has been carried out in the field of nanofluid based solar collector, leading towards the enhancement of working efficiency even at low atmospheric temperature or at low sunlight levels regions of the world. The present review pertains to the research progress related to the performance execution of solar collector using nanofluid. It is observed that the thermal energy storage system (TES), using solar collector, is a useful device for storing sensible and latent heat in a unit volume. Nanofluid plays an important role in various thermal applications such as heat exchanger, solar power generation, automotive industries, electronic cooling system, etc. The nanoparticles find the use in various industrial applications because of its properties, such as thermal, mechanical, optical and electrical. Most of the investigations carried out earlier on the applications of nanofluid in solar energy are related to their uses in the solar collector and thermal storage system. The parabolic solar collector using nanofluid is still a challenge. This article presents an exhaustive review of thermal storage system using nanofluid based solar collector and a scope of using nanofluid based solar collector for performance enhancement.
Numerical Comparison of Thermal Behaviour Between Ventilated Facades
Authors: Schabowicz Krzysztof , Zawiślak Łukasz
Published: May 2020

Increasingly high demands on environmental protection are intensifying the development of sustainable construction. Ventilated facades can provide an energy-efficient alternative to standard facades, that is, external thermal insulation composite systems (ETICS). The article compares standard facades, which was a reference, to ventilated facades in two variants: closed joints and open joints. The comparison was made by means of numerical simulations of computational fluid dynamic (CFD), under conditions of high outside temperature and high sunshine. The results showed great benefits of using ventilated facades in such external climate conditions. It was also observed that the selection of the variant of ventilated facade in the system of close or open joints has minimal influence on thermal efficiency of the whole partition.
Arabic and Islamic Philosophy and Sciences: Method and Truth
Authors: Moubarez Hany
Published: May 2020

What are Arabic and Islamic philosophy and sciences? How and where did they come about? I am trying in this preface to provide a short and brief answer to those two questions. Having done this, I sketch the contents of five papers trying to study Arabic and Islamic philosophy and sciences from its perspective to method and truth.
Three Notes on the Method of Analysis and Synthesis in its Ancient and (Arabic) Medieval Contexts
Authors: Moubarez Hany
Published: May 2020

Most historians and philosophers of philosophy and history of mathematics hold one interpretation or the other of the nature of method of analysis and synthesis in itself and in its historical development. In this paper, I am trying to prove – through three points – that, in fact, there were two understandings of that method in Greek mathematics and philosophy, and which were reflected in Arabic mathematical science and philosophy; this reflection is considered as proof also of this double nature of that method. Thus, we have to rethink the nature of Arabic philosophy systems.
Productivity Losses Due to Migraine in Slovenia: An Analysis of Absenteeism and Presenteeism Costs Based on Administrative and Self-Reported Data
Authors: Lotrič Dolinar Aleša , Žvan Bojana , Došenović Bonča Petra
Published: May 2020

Introduction

Migraine is associated with significant morbidity and a significantly negative impact on the quality of life. A better understanding of the economic impact of migraine is becoming increasingly important. This paper aims to shed light on absenteeism and presenteeism costs of migraine in Slovenia.

Methods

We use the administrative national-level database on sick leave due to migraine for 2016. The absenteeism cost estimate is based on the number of patients with migraine on physician-determined sick leave and average daily labour costs. We calculate productivity costs from a social perspective regardless of who incurs them. Data from the national registry on sick leave are coupled with data from a web-based self-reported survey to also include the cost of presenteeism. MIDAS and WPAI presenteeism items were used and several different scenarios were designed to assess presenteeism costs.

Results

We estimated annual absenteeism costs per absentee due to migraine at the amount of EUR 531 in 2016 using the NIPH’s administrative data on sick leave. Annual absenteeism costs per absentee due to migraine based on self-reported data amounted to EUR 626. The estimated annual presenteeism costs per patient range from EUR 344 – 900.

Conclusion

Estimating the economic burden of a disease is becoming increasingly important. This paper is an insight into the absenteeism and presenteeism costs of migraine in Slovenia.
Long-Term Effectiveness and Cost Effectiveness of Multiple Myeloma Treatment Strategies for Elderly Transplant-Ineligible Patients in Serbia
Authors: Vukićević Đurđa , Rochau Ursula , Savić Aleksandar , Schaffner Monika , Jevđević Milica , Stojkov Igor , Sroczynski Gaby , Willenbacher Wolfgang , Jahn Beate , Siebert Uwe
Published: May 2020

Introduction

Evidence on long-term effectiveness and cost effectiveness of treatment sequences for multiple myeloma (MM) is sparse. We used published data and country-specific data to assess the cost effectiveness of four-line treatment sequences for elderly transplant-ineligible patients with MM in Serbia.

Method

We developed a Markov cohort model to compare long-term effectiveness and cost effectiveness of five sequential MM treatment alternatives from the perspective of the national healthcare provider. Effectiveness parameters on progression, mortality and adverse events were extracted from published clinical trials. Costs were based on price lists of the National Health Insurance Fund. We compared life expectancy, costs, and incremental cost-effectiveness ratios among alternative courses of action. The model was analyzed over a lifelong time horizon applying a 3% annual discount rate for effectiveness outcomes and costs. Robustness of the model was tested in multiple deterministic sensitivity analyses.

Results

The sequences were defined by the frontline treatment: MPT (melphalan-prednisone-thalidomide), MPV (melphalanprednisone-bortezomib), CTD (cyclophosphamide-thalidomide-dexamethasone), VCD (bortezomib-cyclophosphamidedexamethasone) and BP (bendamustine-prednisone). MPV sequence resulted in the highest remaining life expectancy (4.76 life years). Cost-effectiveness analysis resulted in three non-dominated strategies: MPT, VCD, and MPV sequences, with an incremental cost-effectiveness ratio of EUR 35,300 per life-year gained (LYG) for VCD and EUR 47,200/LYG for MPV relative to MPT.

Conclusion

MPV sequence was the most effective in terms of life expectancy for elderly transplant-ineligible MM patients in Serbia. Bortezomib-based strategies would be recommended for the frontline treatment of patients with MM in Serbia if the willingness-to-pay threshold is around EUR 35,000-60,000/LYG.
Physicians’ Attitudes toward Adolescent Confidentiality Services: Scale Development and Validation
Authors: Jeremić Stojković Vida , Cvjetković Smiljana , Matejić Bojana
Published: May 2020

Introduction

Confidentiality is one of the oldest ethical principles in healthcare. However, confidentiality in adolescent healthcare is not a universally-accepted doctrine among scholars. The ethical acceptability of confidential services in adolescents’ healthcare is based on perceptions of adolescent maturity and an appreciation of its importance to adolescents’ access and utilization of healthcare services. Despite legal policies that promote adolescents’ rights, physicians’ attitudes toward adolescent confidentiality can be a determining factor in their ultimate decision to protect adolescents’ confidentiality.

Method

A new Attitude towards Adolescent Confidentiality Scale was developed based on the results of a qualitative interview study. This new instrument was administered to a sample of 152 physicians working at school pediatric and gynecology departments in 13 primary healthcare institutions in Belgrade. Principal component analysis was applied to determine the main components of the scale. Reliability was assessed by calculating Cronbach alpha and mean inter-item correlations.

Results

Psychometric analysis of the final 19-item version of the scale showed a high level of reliability (Cronbach alpha of 0.83). Principal component analysis showed four components, which present subscales of the instrument: Confidentiality in clinical situation, Iimportance of confidentiality, Adolescent maturity, and Communication with parents.

Conclusions

The instrument showed satisfactory levels of reliability and validity. The results of the scale dissemination may be a valuable tool for needs assessment for future educational interventions and training programs that will raise physicians’ awareness of the importance of adolescent confidentiality.
What Attaches Individuals to Groups and Society. A European Comparison
Authors: Paugam Serge , Beycan Tugce , Suter Christian
Published: May 2020

By extending the analytical perspective of Durkheim, we set a theoretical framework to examine social bonds at two levels: the attachment of individuals to each other and the attachment of individuals to society. We create statistical indicators for comparing European countries and also, on an exploratory basis, the regions of Switzerland. We can distinguish and validate four ideal types of attachment regimes (familialist, voluntarist, organicist and universalist). Furthermore, our analysis shows national and regional specificities.
Gender Gap in the Career Success of University Graduates: Effects of Work-Related Values
Authors: Zimmermann Barbara
Published: May 2020

The article deals with the unequal career outcomes between women and men. The data from the graduate survey are used to investigate the effect of work-related values on career success. The Oaxaca-Blinder decomposition determines which factors can explain the gender difference. The results show that career aspirations have a more positive effect on men than on women and that a considerable proportion of the gender gap remains unexplained.
Soft and Hard Skills in Accounting Field-Empiric Results and Implication for the Accountancy Profession
Authors: Cernușca Lucian
Published: May 2020

The main objective of the research is to study the perception of students in accounting profile within the "AurelVlaicu" University of Arad in comparison with the employers’ perception of the hard and soft skills needed in view of the accounting graduates’ access on the labour force market. The target group has been asked to express its opinion on the skills required to candidates to access the jobs in order to penetrate the labour force market in the field of accounting. In order to achieve this objective, an empirical study based on a cross-cutting descriptive research has been carried out, the method chosen is the survey based on a questionnaire. The target group consists of 250 students majoring in accounting within "AurelVlaicu" University of Arad, as well as from 300 professional accountants who are members of CECCAR (The Body o Experts and Chartered Accountants of Romania). The case study concluded that a large part of the interviewed accountants have considered that employers would be increasingly interested in hiring young graduates in accounting that hold strong soft skills, being also willing to subsequently invest in trainings to develop their hard skills that they need daily in the chosen job. In order to succeed and perform in the field in which they will work, accounting students (future accounting professionals) must hold a set of powerful soft skills to complete the hard skills acquired and tested during the academic studies. The target group interviewed in the case study considers it would be useful the accounting students to participate in internships, scientific sessions, Erasmus scholarships, voluntary actions, Work and Travel Programs, teambuilding programs, national and international projects, summer schools, student scientific clubs to develop hard and soft skills during the university studies. In order to generate sustainable organisational success, future professionals who will be working in the field of accountancy will have to possess both hard skills and soft skills to be able to contribute in this way to the success of the organization they will be part of and the accounting profession will gain.
Scoring Model for the Detection of Fake News
Authors: Pop Mihai-Ionuț
Published: May 2020

Misinformation has always existed and has been promoted by groups of individuals, who share the same interests, in order to reach ideological, political or financial goals. In recent years, the emergence of the Internet and social platforms has opened a new and larger dimension in the dissemination of false content and information. With the help of these new technological means, the process of manipulation has evolved and reached a new level which materialized in the concept of fake news. The negative effects associated with this phenomenon have aroused interest among specialists, who are striving to find efficient instruments in order to combat the dissemination of fake information.

In this context, I have developed a scoring model for the detection of fake news, which aims to combat the spreading of false information regarding specialized economic sectors, such as the energy field. Moreover, the model could also be implemented as an important instrument in the fighting against this negative phenomenon that can affect the way public figures, institutions, companies or industries are being perceived by the public opinion.
Using Electrical Capacitance Tomography System for Determination of Liquids in Rocket and Satellite Tanks
Authors: Gut Zbigniew
Published: May 2020

One of important problems in aerospace engineering is to determine the amount of fluid in the tank in a microgravity environment. There are several methods for doing it, however, there are no proven methods to quickly gauge the amount of propellant in a tank in low gravity conditions. New and more accurate methods of such a measurement are being continually searched for. One of interesting solutions is using Electrical Capacitance Tomography (ECT) for this purpose. The article presents both numerical analysis and experimental test results using a spherical tank. The main purpose of the simulation was to determine the effect of the number of electrodes and noise signal level on the quality of reconstruction images. In numerical simulations, different models of dielectric permittivity distribution have been reconstructed. On the basis of numerical simulations, a 24-electrode sensor was designed and made. In experimental tests, different distribution of medium inside the spherical tank was investigated. The results show that the method can directly measure the mass of fuel in the tank, as well as it allows for a visualization of fuel distribution, independent of the tank position in space, and the liquid-propellant system will be used.
The Finite Element Method as a Tool to Solve the Oblique Derivative Boundary Value Problem in Geodesy
Authors: Macák Marek , Minarechová Zuzana , Čunderlík Róbert , Mikula Karol
Published: May 2020

In this paper, we propose a novel approach to approximate the solution of the Laplace equation with an oblique derivative boundary condition by the finite element method. We present and analyse diverse testing experiments to study its behaviour and convergence. Finally, the usefulness of this approach is demonstrated by using it to gravity field modelling, namely, to approximate the solution of a geodetic boundary value problem in Himalayas.
Instantly Decodable RaptorQ Intersessions in Vehicular Adhoc Networks
Authors: Vineeth Nandhini , Guruprasad H. S.
Published: May 2020

Vehicular networks that deal with sharing of information among vehicles are gaining popularity among the automobile industry as well as the researchers. These networks are prevalent under the umbrella of Intelligent Transportation Systems (ITS) and deal with data that belongs to either the emergency category or the entertaining category. In case of emergency services, it is clear that - earlier the reception of information, lesser the commotion. The objective of this work thus has been the reduction of the end to end delay when video files are exchanged among vehicles during intersessions. The set objective is accomplished through the design and development of the technique “Instantly Decodable RaptorQ Inter-Sessions” (IDRQIS) for Vehicular Adhoc Networks and the results obtained show that this outperforms the existing popular techniques – the Network Coding and RaptorQ when applied independently to the same environment. This technique can also be applied to the upcoming unmanned vehicles.
Modelling Wholesale Company’s Supply Chain Using System Dynamics
Authors: Kiisler Ain , Hilmola Olli-Pekka
Published: May 2020

Research is based on wholesale and distribution operations of real-life case company, and in this setting, the most critical part of company’s supply chain is the inventory replenishment to warehouse (Distribution Center) as well as fulfilling and delivering customers’ orders. Different Economic Order Quantity (EOQ)-based models have been considered (Reorder Point, Reorder Point with pipeline on order inventory, and “pulse train”). Simulation system evaluates annual total logistics costs. Results show that in an environment, where local warehouse inventory levels are rather high and replenishment order quantity is rather small, it is important have frequent shipments divided in suitable intervals. In simulation model, this could be done e.g. with the use of “pulse train” function or incorporating pipeline on order inventory in order decision. The research findings are valid for a small-scale supply chain servicing small and geographically limited markets with clients assuming high customer service levels (e.g. 24-hours lead time). For bigger markets, the cross-docking based supply chain models are worth considering in simulations.
KEEFEKTIFAN PERANGKAT PEMBELAJARAN INVESTIGATION BASED MULTI REPRESENTATION UNTUK MENINGKATKAN KETERAMPILAN PEMECAHAN MASALAH
Authors: Retno Safitri Kurnia , Jatmiko Budi , Sudibyo Elok
Published: May 2020

Tujuan penelitian ini adalah untuk menganalisis keefektifan perangkat pembelajaran model Investigation Based Multi Representation (IBMR) yang telah dikembangkan dan melalui tahap validasi untuk membantu meningkatkan keterampilan pemecahan masalah siswa. Desain yang digunakan adalah one group pre-test post-test, yang diterapkan pada materi Hukum Newton kelas X MIA di SMA Negeri 18 Surabaya. Data penelitian dikumpulkan dari nilai pre-test dan post-test siswa dan hasil pengamatan keterlaksanaan pembelajaran dan aktivitas siswa. Hasil tes keterampilan pemecahan masalah dianalisis menggunakan uji-t berpasangan dan n-gain. Hasil penelitian menunjukkan bahwa pembelajaran menggunakan model IBMR adalah efektif untuk meningkatkan keterampilan pemecahan masalah siswa dengan kategori sedang. Peningkatan keterampilan pemecahan masalah siswa menggunakan model IBMR didukung berdasarkan keterlaksanaan pembelajaran dan aktivitas siswa dengan kategori baik.
Hubungan Kompetensi Lulusan Sarjana Ekonomi Syariah dengan Dunia Kerja
Authors: Zulkifli Zulkifli , Murdiana Deswita
Published: May 2020

Penelitian ini bertujuan untuk mengetahui hubungan kompetensi lulusan sarjana ekonomi syariah dengan dunia kerja dan untuk mengetahui upaya yang dilakukan Fakultas Agama Islam Universitas Islam Riau Program Studi Ekonomi Syariah dalam mempersiapkan kompetensi lulusan sarjana ekonomi syariah tersebut, sehingga berdaya guna dan memiliki kompetensi yang berkualitas.
Anti-Kasha System by Design: A New Gateway for Cell Differentiation Through Machine Learning
Authors: Gong Junyi , Wei Peifa , Liu Junkai , Chen Yuncong , zhao zheng , Zhao Weijun , Ma Chao , Lam Jacky W. Y. , Wong Kam Sing , Li Ying , Tang Ben Zhong
Published: May 2020

Kasha’s rule, which claimed that all emissions of excitons are from the lowest excited state and independent of excitation energy, makes the utility of high energy excitons difficult and severely hinder the widespread application of organic photoluminescent materials in real-world. For decades, scientists try to break it to unleash the power of high energy excitons but get minimal progress, no rational guiding principles, and few applications. So far, anti-Kasha’s rule is still a purely academic concept. In this contribution, we proposed a designing principle for pure organic anti-Kasha’s rule system and synthesized a series of compounds by following this designing rule which are all display evident S 2 emission in dilute solutions as proposed. Besides, we introduced a convolutional neural network as an assistant to apply the anti-Kasha’s rule luminogens to cell differentiations with high accuracy (~98.3%), which provide a new direction of applications of anti-Kasha system.
On the Local Charge Inhomogeneity and Lithium Distribution in the Superionic Argyrodites Li6PS5X (X = Cl, Br, I)
Authors: Minafra Nicolo , Kraft Marvin , Bernges Tim , Li Cheng , Schlem Roman , Morgan Benjamin , Zeier Wolfgang
Published: May 2020

The lithium-argyrodites Li6PS5X (X = Cl, Br, I) exhibit high lithium-ion conductivities, making them promising candidates for use in solid-state batteries. These solid electrolytes can show considerable substitutional X−/S2− anion-disorder, with greater disorder typically correlated with higher lithium-ion conductivities. The atomic-scale effects of this anion site-disorder within the host lattice—in particular how lattice disorder modulates the lithium substructure—are not well understood. Here, we characterize the lithium substructure in Li6PS5X (X = Cl, Br, I) as a function of temperature and anion site-disorder, using Rietveld refinements against temperature-dependent neutron diffraction data. Analysis of these high-resolution diffraction data reveals an additional lithium position previously unreported for Li6PS5Xargyrodites, suggesting that the lithium conduction pathway in these materials differs from the most common model proposed in earlier studies. Analysis of the Li+ positions and their radial distributions reveals that greater inhomogeneityof the local anionic charge, due to X−/S2− site-disorder, is associated with more spatially-diffuse lithium distributions. This observed coupling of site-disorder and lithium distribution provides a possible explanation for the enhanced lithium transport in anion-disordered lithium argyrodites, and highlights the complex interplay between anion configuration and lithium substructure in this family of superionic conductors.
How Does the Novel Coronavirus Interact with the Human ACE2 Enzyme? A Thermodynamic Answer
Authors: de Andrade Jones , Gonçalves Paulo Fernando Bruno , Netz Paulo Augusto
Published: May 2020

The SARS-CoV-2 coronavirus pandemic is certainly the most important public health concern today. Until now there are no vaccines or treatments available, despite intensive international efforts. One of the targets for new drugs is the Coronavirus Spike Protein, responsible for its binding and entry into the host cells. The Receptor Binding Domain (RBD) found at the Spike Protein recognizes the human angiotensin-converting enzyme 2 (hACE2). The present in silico study discuss structural and thermodynamic aspects of the protein complexes involving the RBD’s from the 2002 SARS-CoV and 2019 SARS-CoV-2 with the hACE2. Molecular docking and molecular dynamics simulations of the complexes and isolated proteins were performed, providing insights on their detailed pattern of interactions, and estimating the free energy of binding. The obtained results support previous studies indicating that the chemical affinity of the new SARS-CoV-2 for the hACE2 enzyme virus is much higher than the 2002 SARS-CoV. The herein calculated Gibbs free energy of binding to the hACE2 enzyme is, depending on the technique, from 5.11 kcal/mol to 8.39 kcal/mol more negative in the case of the new coronavirus’ RBD. In addition, within each employed technique, this free energy is consistently 61±2% stronger for SARS-CoV-2 than for SARS-CoV. This work presents a chemical reason for the difficulty in treating the SARS-CoV-2 virus using drugs targeting its Spike Protein, as well as helps to explain its infectivity, while defining a minimum free energy of binding for new drugs to be designed against this disease.
Myricetin Preferentially Binds to Interfacial Regions in Domains 1 – 3 to Inhibit Cholesterol-Dependent Cytolysins: A Molecular Docking Study
Authors: Espiritu Rafael
Published: May 2020

Cholesterol-dependent cytolysins (CDCs) are proteinaceous toxins secreted as monomers by some Gram-positive and Gram-negative bacteria that contribute to their pathogenicity. These toxins bind to either cholesterol or human CD59, leading to massive structural changes, toxin oligomerization, formation of very large pores, and ultimately cell death, making these proteins promising targets for inhibition. Myricetin, and its related flavonoids, have been previously identified as a candidate small molecule inhibitor of specific CDCs such as listeriolysin O (LLO) and suilysin (SLY), interfering with their oligomerization. In this work, molecular docking was performed to assess the interaction of myricetin with other CDCs whose crystal structures are already known. Results indicated that although myricetin bound to the hitherto identified cavity in domain 4 (D4), much more efficient and stable binding was obtained in sites along the interfacial regions of domains 1 – 3 (D1 – D3). This was common among the tested CDCs, which was primarily due to much more extensive stabilizing intermolecular interactions, as indicated by post-docking analysis. Specifically, myricetin bound to (1) the interface of the three domains in anthrolysin O (ALO), perfringolysin O (PFO), pneumolysin (PLY), SLY, and vaginolysin (VLY), (2) at/near the D1/D3 interface in LLO and streptolysin O (SLO), and (3) along the D2/D3 interface in intermedilysin (ILY). These findings provide theoretical basis on the possibility of using myricetin and its related compounds as a broad-spectrum inhibitor of CDCs to potentially address the diseases associated with these pathogens.
Aggregation Induced Emission in the Tetraphenylthiophene Crystal: The Role of Triplet States
Authors: Stojanovic Ljiljana , Crespo Otero Rachel
Published: May 2020

Propeller-shaped molecules have received much attention due to their enhanced emission in the condensed phase (Aggregation Induced Emission, AIE) and their potential use in optoelectronic devices. In this contribution, we examine the excited state mechanisms of tetraphenyl-thiophene (TPT), one member of the family which features weaker AIE. We perform a detailed analysis of the potential energy surfaces with special focus on the role of triplet states considering the crystal structure, intermolecular interactions, exciton couplings and reorganisation energies in the vacuum and solid state. In contrast with other members of the propeller-shaped family, nonradiative decay in TPT is driven by bond breaking. Because of the significant spin-orbit couplings along the reaction coordinate, intersystem crossing plays an important role in the mechanism. Our calculations show that aggregation in the solid state hampers the access to internal conversion pathways, however, intersystem crossing is active in the crystal phase, which explains the weak AIE of this molecule. This new understanding of the role of triplet states on the relaxation mechanisms of AIEgens has implications for the design of solid state highly-emissive materials based on TPT.
Possible role of traditional medicinal plant Neem (Azadirachta indica) for the management of COVID-19 infection
Authors: Roy Shuvrodeb , Bhattacharyya Pradip
Published: May 2020

Novel coronavirus disease (COVID-19) originated from Wuhan, China. Afterwards COVID-19 outbreak was declared as a Public Health Emergency of International Concern by World Health Organization (WHO). Now around two and half million peoples are suffering and several thousands are dead worldwide due to the highly infectious and deadly nature of the virus. Unfortunately, no standard medicine or vaccine is available to treat the disease. The major clinical symptoms for COVID-19 are fever, chills, cough, fatigue, respiratory symptoms, diarrhoea and shortness of breath. Clinical symptom based Indian traditional medicinal practices like Ayurveda and Siddha could be beneficial to treat and prevent the infection. Indian origin traditional medicinal plant Neem (Azadirachta indica) has been reported to have anti-viral potential against bovine herpes virus type-1, poliovirus type 1, duck plague virus, dengue virus type-2, newcastle disease virus, infectious bursal disease virus, avian influenza virus and group B coxsackievirus. Neem is widely used as Ayurvedic medicine to treat fever, cough, asthma and diarrhea which are also reported as the common clinical symptoms for COVID-19. Neem is recorded to enhance both humoral and cell mediated immune response during viral infection. Multidimensional anti-viral therapeutic potentials of Neem insist to hypothesize its probable application to control COVID-19 along with modern medicinal practices. But, series of experimental database and translational research are required to establish the hypothesis.
A brief analysis of new media pushing "The Belt and Road" Initiative
Authors: Xiao Kaiqiang , Chen Liang
Published: May 2020

Abstract: in 2013, President Xi put forward the strategic ideas of "Silk Road Economic Belt" and "21st Century Maritime Silk Road" during his visit to central Asia and South Asia, which gained extensive attention from the international community. To promote the implementation of the "The Belt and Road" initiative, it is necessary to not only build good infrastructure to promote economic and trade exchanges between countries, but also create a good public opinion environment to enhance exchanges and mutual trust between countries. New media, as one of the main channels of information communication in the current era, plays an important role in spreading the culture of "The Belt and Road" initiative and promoting economic cooperation among countries with its characteristics of flexibility, interactivity and high efficiency. Exploring the role of new media in promoting the political, cultural and economic aspects of the "The Belt and Road" initiative will be of great significance to mastering the power of discourse of the Silk Road and strengthening the exchanges and cooperation among countries along the route.
Study on Approaches and Methods for Cultivation of Young Marxists in Colleges and Universities
Authors: Cui Yugai
Published: May 2020

The Central Committee of the Communist Party of China greatly pushes forward young Marxists training projects, thus study on approaches and methods for cultivation of young Marxists in colleges and universities is of great significance for establishment of socialism with Chinese characteristics for a new era. However, current problems include: current young Marxists projects in colleges and universities are based on theoretical research; over-reliance on research results in the recent years, and lack of in-depth systematic research on writing thoughts of classical literature; lack of accurate assessment mechanism for practical activities; insufficient innovation of training methods; poor quality of training environment. Actively searching for relevant improvement measures based on the current problems has positive effects in promoting cultivation of young Marxists in colleges and universities.
Teología, filosofía y ciencia ante la cuestión del hombre: Una aproximación desde el planteamiento de Max Scheler
Authors: JIMÉNEZ EMILIO
Published: May 2020

La tensión entre la Filosofía, la Teología y la Ciencia en el caso concreto del tema y el problema del hombre, es una cuestión históricamente dada. La problemática humana, cuestión susceptible de encararse filosófica, teológica o científicamente, ha impulsado la navegación teórica de filósofos, teólogos y científicos. Max Scheler afirma que no hay una idea unitaria del problema del hombre; en su defecto hay tres grandes círculos de ideas: griega, judeocristiana y “científica”. En este escenario surge la curiosidad por explorar la razón de esta falta de unidad a partir de postular el hecho que con frecuencia triunfa la exclusión entre protagonistas de estos tres grandes círculos de ideas antes que, como se pudiera esperar, la complementariedad y la armonía. Tanto la “ciencia” como la teología recurren a la “autoridad”, el paradigma de la comunidad científica o la Biblia, pero las grandes preguntas formuladas alrededor del fenómeno humano reclaman incesantemente horizontes de respuesta más allá de un pretendido agotamiento de los mismos en la ciencia experimental o la teología, es decir, hubo y habrá lugar para la filosofía, más aún, resulta imperativo que lo haya, si por otra parte, una idea unitaria es imposible donde cualesquier dogmatismo acrítico se impone o intenta imponerse. No parece factible encarar la complejidad de lo humano sin el examen, la reflexión y la crítica a partir de los aportes de la ciencia, ni tampoco en ausencia de postulados cuya razonabilidad depende de la autoridad; en suma, el camino hacia la comprensión del hombre es una empresa de carácter filosófico en tanto se da en la línea de una perspectiva e idea unitaria.
Violencia de género aprendida en la narrativa de las canciones modernas
Authors: A’Lmea Suárez Rosario De Fátima
Published: May 2020

Este artículo académico se adjunta a la línea de análisis que desnaturaliza las prácticas contemporáneas de construcción de ciudadanías e identidades sociales a través de los medios de comunicación, que actúan a la par del currículo oficial, educando de manera indirecta bajo formas hegemónicas de género. Así, el tema se centra en la narrativa de las letras de las canciones. El lector apoyará la necesidad de lecturas críticas para los textos sociales, de aparente entretenimiento. Para un diálogo teórico he recurrido a las propuestas post-estructuralistas y pos-críticas, aplicadas al material del mundo simbólico, como la lengua, por ello, usaré presupuestos de la comunicación, de la semiótica, de la pragmática. De manera central, recurriré a la narratología, una técnica de lectura que parte de los elementos diegéticos para interpretar; de ellos me interesa la focalización pues devela la perspectiva ideológica, de poder y cómo se dan las relaciones internas.
THE ROLE OF LAW ENFORCEMENT AGENCIES IN ENSURING THE PRINCIPLE OF LEGALITY DURING THE GREAT PATRIOTIC WAR
Authors: Ahmedov Ruslan , Ivanova Yuliya
Published: May 2020

In 2020, the 75th anniversary of the Victory of the soviet people is celebrated over fascism. An important role in achieving this result in the conditions law enforcement officers also provided wartime assistance. The main purpose of their professional activities was to ensure the implementation of principles of legality.
PROBLEMS OF RECOGNITION OF A CITIZEN DIED IN CIRCUMSTANCES GIVING A BASIS TO ASSUME ITS DESTRUCTION
Authors: Tischenko Irina , Durneva Natal'ya
Published: May 2020

This article discusses the legal consequences of recognizing a citizen as dead, lists the circumstances under which a person may be presumed dead, assesses current legislation in this area. The issues of improving civil legislation in the field of recognition of a person as deceased are raised. The article indicates the period during which a person may be presumed dead under circumstances giving reason to believe his death. The necessity of taking measures aimed at expanding the rights of a person declared dead under circumstances giving reason to believe that he was killed in the event of his appearance or finding a place of residence is emphasized.
SECTANITY IN THE CONTEXT OF MANIFESTATIONS OF MODERN RELIGIOUS EXTREMISM
Authors: Agapov Pavel , Stepkin Kirill
Published: May 2020

The article considers the general theoretical foundations of the relationship of sectarianism and religious extremism in the Russian Federation. Practical examples of the role of destructive sects in modern religious extremism in the Russian Federation are given.
PROBLEMS OF INTERACTION BETWEEN INTERNAL AFFAIRS BODIES AND CUSTOMS AUTHORITIES OF THE RUSSIAN FEDERATION IN THE FIELD OF COUNTERING THE ILLEGAL USE OF A TRADEMARK
Authors: Bobyleva Marina
Published: May 2020

In his article, the author reveals the main aspects of the activities of counteracting the illegal use of a trademark as an object of intellectual property.
THE RELATIONSHIP BETWEEN INSULIN RESISTANCE AND FA-TIGUE SYMPTOM IN FIBROMYALGIA SYNDROME
Authors: Turgay Türkan , Kirmaci Zekiye İpek Katirci , Karadeniz Pınar Günel , Baştemir Mehmet
Published: May 2020

The aim of this study is to examine the relationship between insulin resistance and fatigue in fi-bromyalgia. A total of 72 patients (4 males, 68 females) with fibromyalgia (FM) was investigated. Patients were divided into two groups by insulin resistance (IR), group 1; IR- (n=49), and group 2; IR+ (n=23). IR was determined using homeostasis model assessment (HOMA) formula. All subjects were evaluated with serum 25 (OH) D vitamin levels. The severity of the disease was measured with the Fibromyalgia Impact Questionnaire (FIQ); the level of fatigue was evaluated with Fatigue Severity Scale (FSS); and the pain level was evaluated with Visual Analog Scale (VAS). There were significant differences between the FIQ and FSS mean scores of two groups (IR+ and IR-), (p=0.031, p=0.005). There were no significant differences between two groups in respect to VAS and serum 25 (OH) D vitamin levels (p=0.789, p=0.875). There was no significant correlation be-tween vitamin D and FSS (IR+, r=-0.263, p=0.225; IR-, r=0.112, p=0.443), and also vitamin D and FIQ (IR+, r=-0.103, p=0.641; IR-, r=0.050, p=0.733) in both groups. There was no relationship be-tween insulin resistance and fatigue symptom in fibromyalgia patients, but it was observed that the severity of fatigue was higher in the group with insulin resistance.
BIOSTRATIGRAPHIC CORRELATION OF PALEOZOIC ROCKS IN NORTHERN AND WESTREN IRAQ
Authors: Al-jubori Falah H. Khalaf , Youkhana Akram K. , Naqshabandi Srood F. , Bayz Dyana A.
Published: May 2020

The Paleozoic rocks outcropped in northern Iraq (Ora, Chia Zairi section) are biostratigraphically investigated for their microfossils content. Benthonic foraminifera and algal genera characterize the upper part of the section while palynomorphs (Miospores & Acritarchs) dominated the lower part the section which is consist of clastic sediments. The study also include the stratigraphic succession of the section and its correlation to the subsurface sections penetrated in oil and  water wells drilled in the western desert of Iraq in order to determine the regional distribution of the economically important formations, either  as reservoir or as source  rocks for hydrocarbons. Index palynomorphs including many types of Acritarch genera are identified in the Khabour Formation indicate lower Ordovician time (Tremadocian? Arenigian –Llanvirnian: age) The Perispik Formation has been found barren of any type of microfossils and is composed of red clastic rocks.

Pollen and Spores are recorded from the "Ore Group"  (Kaista, Ora and Harur Formations )  indicate that these rocks are of Upper Devonian – Lower Carboniferous  (Famennian – Tournaisian age ) .A Large number of  foraminifera and Algal genera are identified in the Chiazairi rocks,these genera and species are indicated the Upper Permian rocks of Thuringian age.

The stratigraphic   succession of the Paleozoic section studied in northern Iraq indicate that there is a stratigraphic break represents by missing of the Ga'ara Formation (late Carboniferous –early Permian) and Akkas Formation (Silurian) and the upper part of the Khabour Formation (Upper Ordovician).
FATORES INFLUENCIADORES DO COMPORTAMENTO DO CONSUMIDOR DE MOBILE BANKING
Authors: De Abreu Audenice Soares , Fonseca e Fonseca Paulo Roberto Campelo
Published: May 2020

Objetiva-se, neste artigo, analisar qual fator norteia o comportamento dos consumidores dos serviços de mobille banking. Dessa forma, o problema da pesquisa é: Qual fator norteador do comportamento do consumidor é mais visível nos usuários do serviço de mobile banking? Para isso foi necessário avaliar os fatores influenciadores do comportamento dos consumidores de mobile banking, os quais são: atitude comportamental, norma subjetiva e controle percebido que fazem parte da TCP decomposto. Ao desenvolver essa pesquisa fez-se a aplicação de questionários por meio do Microsoft formulários, com 167 usuários do mobile. O método de pesquisa utilizado foi dedutivo, de abordagem qualitativa e quantitativa, e aplicada pelo uso da escala Likert. A partir da pesquisa foi possível analisar informações dos respondentes com relação aos constructos aqui estudados, com isso observou-se que o fator atitude foi o que mais se destacou na intenção comportamental com relação aos outros fatores. Conclui-se que as pessoas são regidas por premissas que contribuem ao seu favorecimento, ou seja, ao seu desempenho e com base naquilo que irá reduzir seus esforços.
An Introduction to Resilience
Authors: Isbister Christian
Published: May 2020

In this short introductory piece I outline some of the struggles faced by MLIS students, ultimately to highlight their resilience in the face of these issues.
Confronting the democratic discourse of librarianship: A Marxist analysis
Authors: McNichol Michael
Published: May 2020

Review of the book Confronting the democratic discourse of librarianship: A Marxist analysis by Popowich, S
Pengelolaan Pemangkasan Tanaman Kakao (Theobroma Cacao L.) Di Cilacap, Jawa Tengah
Authors: Angela . , Efendi Darda
Published: May 2020

Penelitian ini berlangsung di daerah Cilacap, Jawa Tengah mulai dari 14 Februari sampai 14 Juni 2011. Tujuan penelitian ini yaitu untuk pengetahuan, pembelajaran dan memahami manajemen pemangkasan kakao di kebun. Aktivitas penelitian terdiri atas teknikal dan aspek manajerial yaitu sebagai karyawan harian lepas selama satu bulan, asisten mandor selama satu bulan, dan sebagai pendamping asisten afdeling selama dua bulan. Data primer diperoleh dari semua aktivitas penelitian dan pengamatan langsung di lapang, sedangkan data sekunder diperoleh dari catatan laporan perusahaan. Pemangkasan yang dilakukan selama penelitian yaitu pemangkasan pemeliharaan. Pemangkasan mempengaruhi jumlah tunas air, bantalan yang berbunga, ketahanan cherelle (pentil buah) dan buah terhadap hama dan penyakit tanaman. Rotasi pemangkasan juga mempengaruhi kestabilan produksi biji tahunan kakao.
Pengaruh Aplikasi Pupuk Organik Dan Pupuk Hayati Serta Reduksi Pupuk NPK terhadap Ketersediaan Hara dan Populasi Mikroba Tanah Pada Tanaman Padi Sawah Musim Tanam Kedua di Karawang, Jawa Barat
Authors: Riyanti Shoni , Purnamawati Heni , Sugiyanta .
Published: May 2020

Penelitian dilakukan di Karawang, Jawa Barat pada bulan Oktober 2010 sampai April 2011. Tujuan penelitian adalah mengetahui pengaruh aplikasi pembenaman jerami dan pupuk hayati serta pupuk organik dalam mengurangi penggunaan pupuk NPK pada musim tanam kedua. Percobaan menggunakan Rancangan Kelompok Lengkap Teracak yang terdiri atas 13 perlakuan. Perlakuan tersebut adalah P1 = jerami + 0.5 dosis NPK, P2 = jerami + 0.5 dosis NPK + pupuk organik granul (POG) + pupuk organik cair (POC), P3 = jerami + 0.5 dosis NPK + POG, P4 = jerami + 0.5 dosis NPK + POG + pupuk hayati 1, P5 = jerami + 0.75 dosis NPK + pupuk hayati 2, P6 = jerami + 0.5 dosis NPK + pukan, P7 = jerami + 0.5 dosis NPK + pupuk hayati 1, P8 = jerami + 0.5 dosis NPK + pupuk hayati 2, P9 = jerami + 1 dosis NPK, P10 = tanpa jerami + 1 dosis NPK, P11 = jerami + 0.5 dosis NPK + pupuk hayati 3, P12 = tanpa jerami + 0.5 dosis NPK + pupuk hayati 3, dan P13 = tanpa pupuk. Hasil penelitian menunjukkan bahwa penerapan pupuk hayati (bio 1, 2, atau 3) dapat meningkatkan ketersediaan hara dan populasi mikroba tanah. Aplikasi ini dipengaruhi jumlah pembentukan batang pada 7 MST dan daun berwarna pada 3 dan 7MST. Jerami + 0.5 dosis NPK + pupuk hayati 2 tidak berbeda signifikan dengan perlakuan 1 dosis NPK.
De lo personal a lo colectivo. "Homenaje al lenguaje" de Eduardo Milán
Authors: López-Carballo Pablo
Published: May 2020

Para tratar de comprender el alcance y la relevancia del trabajo poético de Eduardo Milán, en las páginas siguientes se propone una aproximación a su obra desde uno de sus textos más emblemáticos, el último poema de Razón de amor y acto de fe (2001), titulado "Homenaje al lenguaje". Este texto nos servirá para explicar los procedimientos y problemáticas abordadas por el poeta uruguayo en sus más de cuarenta y cinco años de escritura. Las dificultades asociadas a la representación serán el principal motivo desde el cual problematizar la compleja relación que mantiene el poema con el mundo, el papel social del escritor o los ví­nculos u oposiciones en torno a los estamentos de poder y sus consecuencias.
Constelaciones metafóricas de la memoria: Sumar de Diamela Eltit
Authors: Cabrera Mario Federico David
Published: May 2020

En este artí­culo me propongo analizar la novela Sumar (2018) de Diamela Eltit a partir de la configuración discursiva de tres tópicos que funcionan como metáforas asociadas a la problemática de la memoria: el cuerpo de la narradora, el desplazamiento de los ambulantes hacia La Moneda y la idea de nube/archivo. Sostengo, a modo de hipótesis, que la noción de memoria se presenta en esta novela como un punto de exploración estética y como una preocupación polí­tica central para pensar el presente.