bluuebunny/crossref_metadata_2025 huggingface dataset:
Infective Endocarditis After Percutaneous Device Closure of Atrial Septal Defects: Incidence, Diagnosis, and Treatment. Case Report and Literature Review
Authors:   GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy, Nasso Giuseppe , Condello Ignazio ,   GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy, D’Abramo Mizar ,   Department of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences,  Sapienza University of Rome, Rome, Italy, De Luca Angelo ,   Department of Clinical and Molecular Medicine, Cardiac Surgery Unit, Sapienza University of Rome,  Sant'Andrea Hospital, Rome, Italy, Larosa Claudio ,   Azienda Ospedaliera BAT, Bonomo Hospital, Andria, Italy, Valenti Giovanni ,   Azienda Ospedaliera BAT, Bonomo Hospital, Andria, Italy, Bartolomucci Francesco ,   Azienda Ospedaliera BAT, Bonomo Hospital, Andria, Italy, Di Bari Nicola Di Bari ,   GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy, Sechi Stefano ,   GVM Care & Research, Department of Cardiovascular Surgery, San Carlo di Nancy, Rome, Italy, Diaferia Giuseppe ,   Azienda Ospedaliera BAT, P.P.A. Canosa di Puglia, Italy, De Rosis Maria Grazia ,   Azienda Ospedaliera Bari, Bari, Italy, Amodeo Vincenzo ,   Ospedale degli Ungheresi, Polistena, Italy, Melina Giovanni ,   Department of Clinical and Molecular Medicine, Cardiac Surgery Unit, Sapienza University of Rome,  Sant'Andrea Hospital, Rome, Italy, Speziale Giuseppe ,   GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy, Vignaroli Walter ,   GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy
Published: January 2024

Infective endocarditis (IE) on atrial septal defect (ASD) closure devices, while extremely rare, has been reported to be more frequent early after the procedure. We describe a case of late IE after percutaneous closure of patent foramen ovale (PFO). We also performed a literature review on this subject. We reviewed a total of 42,365 patients who were treated with percutaneous devices: 13,916 for ostium secundum (OS) (32%), 24,726 for PFO (58%) and 3,723 for OS+PFO (8%). Among these patients, we identified 50 cases of IE after atrial septal defect device closure (0.001%). In contrast to previous reports, nearly 66% of IE in this setting occurred late, after at least 6 months from the procedure (33/50 patients). A statistical analysis clearly showed that the mean time from the procedure to IE increased in the last five years, probably associated with a change in antiplatelet therapy after ASD closure. Management of IE on an ASD occluder should always be discussed in the setting of a multidisciplinary heart team that includes a cardiologist, cardiac surgeon, and anesthetist. While surgical strategies gave excellent results, conservative management might be considered in cases of small IE vegetations and for patients in good general condition. However, in these cases, the patient must be closely observed with repeated blood and instrumental tests.
Odds of Mortality in Geriatric Patients with Appendicitis is 22 Times Higher than that in Non-Geriatrics: An Analysis of 336,880 Patients from NIS Database
Authors:   New York Medical College, School of Medicine, Valhalla, New York, Hirani Rahim , Smiley Abbas ,   School of Medicine and Dentistry, University of Rochester, Rochester, New York, Latifi Rifat ,   Abrazo West Campus, Phoenix, Arizona
Published: January 2024

Introduction: Our goal was to identify risk factors for mortality in adult (18–64 years) and geriatric (65+ years) patients admitted with a primary diagnosis of appendicitis. Materials and Methods: The data was obtained from the National Inpatient Sample for patients admitted emergently with appendicitis (ICD-9 540-542) between 2005–2014, and then retrospectively analyzed using multivariable logistic regression with backward elimination. Results: A total of 336,880 patients were included in the cohort. Mean age was 37.7 and 73.8 years in adult and elderly patients, respectively. 97.3% of adults and 94.2% of elderly patients underwent an operation. The mortality rate in the elderly patients (1.04%, n=402/38,509) was 22 times higher (p<0.0001) than that in adult patients (0.047%, n=144/301,408). Mean (SD) hospital length of stay (HLOS) was 2.6 (2.9) days in adults and 4.9 (5.2) days in elderly patients (p<0.0001). Ninety-nine percent of adult and elderly patients were discharged within 11 and 20 days after emergent hospitalization, respectively. In the final regression model, every one year older in age increased the odds of mortality by 5% (OR=1.05, 95%CI: 1.04–1.06, p<0.001), and for every one day longer, HLOS increased the odds of mortality by 1% (OR=1.01, 95%CI: 1.001–1.02, p<0.001). The multivariable logistic regression model was built on 82,006 patients whose HLOS was ≥4 days, the odds ratio for HLOS was 1.05 (95%CI: 1.04–1.06). This means that for every additional day in hospital after day 4, the odds of mortality increase by 5%. Conclusion: The risk of mortality in elderly patients admitted emergently with appendicitis is approximately 22 times higher than that of non-elderly adults.
The Novel Use of Bipolar Radiofrequency Microneedling in the Treatment of Lichen Sclerosus
Authors:   Advanced Women’s Health Care of the Lowcountry, PC, Hilton Head, South Carolina, Blusewicz Tracy A. , Coley Katherine P. ,   Advanced Women’s Health Care of the Lowcountry, PC, Hilton Head, South Carolina, Moore Robert D. ,   Miklos and Moore Urogynecology, Atlanta, Georgia, Miklos John R ,   Miklos and Moore Urogynecology, Atlanta, Georgia
Published: January 2024

Introduction: Lichen sclerosus (LS) is a chronic, distressing, inflammatory process that has a huge impact on quality of life in women. Uncontrolled vulvar LS can lead to chronic symptoms of itching and pain and can lead to anatomic changes, scarring, and elevated risk of cancer. First-line therapy with corticosteroids is often not successful in controlling symptoms, especially over the long term. This is the first study to review the effects of bipolar radiofrequency (RF) with microneedling to treat the vaginal and vulvar symptoms of LS. Materials and Methods: This retrospective study was initiated due to the recognition of improvement in vulvar skin condition and resolution of lichen sclerosus symptoms in patients who had already failed traditional treatment and underwent radio frequency with microneedling procedures of the vulva, perineum, and perianal regions. Patients were treated with three treatments of bipolar RF and bipolar RF with microneedling four to eight weeks apart. Patient questionnaires were used to assess improvement in the symptoms of LS including itching, tearing of tissue, changes in the appearance and color of tissue, and dryness of skin and mucosa. Results: The data from the questionnaires showed a significant reduction or complete resolution in these symptoms, with 86% of the patients reporting either significant or complete resolution. In the case of itching, which is typically one of the most severe symptoms of LS, 91% of patients reported significant or complete resolution. 87% of patients reported symptom resolution lasting at least six months, with 39% of the patients having results lasting 12 months or more before recurrence. Recurrences can be retreated on an as-needed basis or with annual maintenance therapy consisting typically of just one treatment. Conclusion: Radiofrequency with microneedling treatments for persistent LS showed significant improvement in LS symptoms. As LS is a chronic recurring condition, the treatment protocol resulted in high patient satisfaction for these women who had not experienced these results in terms of amount of symptom resolution or duration of symptom resolution with prior treatments using topical steroid cream or other modalities.
Does Preoperative Statin Exposure Reduce Prosthetic Joint Infections and Revisions Following Total Joint Arthroplasty?
Authors:   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Sax Oliver C. , Chen Zhongming ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Bains Sandeep S. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Jacobstein Danielle A. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Dubin Jeremy A. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Hameed Daniel ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Moore Mallory C. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Mont Michael A. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Nace James ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Delanois Ronald E. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland
Published: January 2024

Introduction: The pleiotropic effects of statins extend beyond managing cardiovascular health and are suggested to modulate Staphylococcus aureus biofilm formation with prosthetic joint infection (PJI) reduction. However, a large analysis of statin use prior to total joint arthroplasty (TJA) to determine infection and revision risk is lacking. We specifically evaluated: 90-day to two-year (1) prosthetic joint infection (PJIs); (2) revisions; and (3) respective risk factors. Materials and Methods: We queried a national, all-payer database for patients undergoing either TKA or THA between 2010–2020. Chronic statin exposure was defined as >3 prescriptions filled within one-year prior to TJA (statin users). A control cohort of patients undergoing TJA without history of statin use prior was identified (statin naïve). Cohorts were matched 1:1 based on demographics and comorbidities (TKA: n=579,136; THA: n=202,092). Multivariate logistic regression was performed to evaluate risk factors for PJIs and revisions. Results: Among TKA recipients, statin users had lower incidence of PJIs at one year (0.36 vs. 0.39%) to two years (0.45 vs. 0.49%) compared to the statin naïve (all, p≤0.007). Similarly, statin users had lower incidence of one- to two-year revisions (all, p≤0.048). Among THA recipients, statin users had lower incidence of PJIs at 90 days (0.37 vs. 0.45%) to two years (2% vs. 2.14%) (all, p<0.001). Similar trends were observed for 90-day to two-year revisions (all, p≤0.022). Statin use was independently associated with decreased odds of PJIs and revisions by one year. Conclusions: Statin use is associated with a reduced risk of PJIs and revisions from one to two years following TJA. It may be worthwhile to ensure patients take statin therapy if indicated for previously established cardiovascular guidelines.
An External Acetabular Alignment Guide Decreases Positional Variance
Authors:   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, Wadhwa Harsh , Warren Shay I. ,   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, Oladeji Kingsley ,   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, Finlay Andrea K. ,   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, Huddleston James I. ,   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California, Amanatullah Derek F. ,   Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, California
Published: January 2024

Introduction: Certain patient and operative factors limit accurate estimation of acetabular component positioning during total hip arthroplasty (THA). This study aimed to determine whether an intraoperative external alignment guide decreases variance in acetabular component positioning. Materials and Methods: Adult patients who underwent primary THA from 2014–2018 were reviewed. Exclusion criteria were navigation, robot-assisted surgery, and inflammatory, post-traumatic, or avascular arthritis. One surgeon used an external guide while the second surgeon resected osteophytes and utilized available anatomical landmarks for positioning. Anteversion and inclination, variance, “safe zone” positioning, operative time, and hip instability were assessed. Multivariable regression models were used to examine effects on primary and secondary outcomes. Results: 409 patients were included, of which 182 underwent component placement with landmarks only. Patients undergoing component placement with landmarks only were younger (p=0.002) and more often smokers (p=0.016). After multivariable risk adjustment, use of the external alignment guide was independently associated with 2.7° higher anteversion (CI: 1.6° to 3.8°) and smaller anteversion variance (-0.3, CI: -0.6 to 0.1) compared to landmarks only. It was independently associated with 3.2° higher inclination (CI: 2.0° to 4.4°), but there was no difference in inclination variance (-0.1, CI: -0.3 to 0.2). The external alignment guide was independently associated with a 14-minute shorter operative time (CI: 9.6 to 18.7) and smaller operative time variance (-0.9, CI: -1.2 to 0.6). Discussion: Use of anatomical landmarks alone was associated with increased likelihood of safe zone positioning but lower precision and longer operative time. While this study was limited by lack of randomization and its retrospective nature, an acetabular positioner may be preferable to palpable or visible anatomy alone for acetabular component placement.
What is the Efficacy of Intra-Articular Platelet-Rich Plasma Injections for Knee Osteoarthritis in Clinical Practice? A “Real-Life” Prospective Cohort
Authors:   Department of Sports Medicine, Cleveland Clinic Florida, Weston, Florida, Oliveira Leonardo , King Dominic ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Genin Jason ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Miniaci Anthony ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Khan Shujaa ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Pasqualini Ignacio ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Rullán Pedro ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Peck Evan ,   Department of Orthopaedic Surgery, Cleveland Clinic Florida, Weston, Florida, Tejpar Farah ,   Department of Orthopaedic Surgery, Cleveland Clinic Florida, Weston, Florida, Gilot Gregory ,   Department of Orthopaedic Surgery, Cleveland Clinic Florida, Weston, Florida, Orr Melisa ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Muschler George F. ,   Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, Piuzzi Nicolas S. ,   Department of Orthopaedic Surgery, Orthopaedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, Ohio
Published: January 2024

Introduction: Platelet-rich plasma (PRP) injections may improve symptoms in patients suffering from knee osteoarthritis. However, there is a lack of data on its effectiveness in a “real-life” cohort. This multi-site institutional registry study aimed to assess patients’ longitudinal progress after PRP injection for knee osteoarthritis. Materials and Methods: All patients receiving PRP injections for knee osteoarthritis at a large, integrated tertiary academic center (December 18, 2017 to March 1, 2021) were eligible. A prospective data collection instrument was used to collect patient demographics, procedural information, and patient-reported outcome measures. Overall, 97 patients met the inclusion criteria, and 53 were included in the analysis. Results: One in four patients (26%) improved on all three Knee Injury and Osteoarthritis Outcome Score subscales: 17% in two subscales and 20% in one subscale, respectively. Overall, 64% of patients improved in at least one patient-reported outcomes measure. At six months post injection, 49% of patients were satisfied. Conclusion: PRP injection provides positive changes in two out of three patients in different magnitudes and characteristics with careful attention to clinically meaningful differences.
A New Hinge Prosthesis Offers Ease of Use and the Ability to Retain the Revision Tibial Baseplate
Authors:   Joint Replacement, Stryker, Mahwah, New Jersey, Hampp Emily L , Hameed Daniel ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Anoushiravani Afshin ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Donde Shilpa ,   Joint Replacement, Stryker, Mahwah, New Jersey, Hatcher Sophie ,   Joint Replacement, Stryker, Mahwah, New Jersey, Dubin Jeremy A. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland, Coulon Kerianne ,   Joint Replacement, Stryker, Mahwah, New Jersey, Mastrandrea Sarah ,   Joint Replacement, Stryker, Mahwah, New Jersey, Weinberg Caroline ,   Joint Replacement, Stryker, Mahwah, New Jersey, LoPiccolo Frank ,   Joint Replacement, Stryker, Mahwah, New Jersey, Mont Michael A. ,   LifeBridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland
Published: January 2024

Total knee arthroplasty (TKA) is a widely practiced surgical procedure, with its efficacy underscored by the increasing number of patients benefiting from it. As primary TKAs rise, the orthopaedic community must prepare for a surge in complex primary and revision knee arthroplasties in the future. While most revisions use non-constrained or semi-constrained prostheses, certain scenarios require a fully constrained (hinge) prosthesis to address major ligamentous and/or bone loss. Over time, hinge designs have evolved, but outcomes with these designs have been mixed. To help address challenges seen with some earlier designs, a new modular revision solution has been designed for both primary and revision surgeries. This system has a new revision baseplate that has compatibilities with varying distal femoral components and introduces an enhanced hinge mechanism. This paper aims to explore the evolution of hinge designs, elaborate on the surgical workflows and intended compatibilities of this new revision hinge system in six different scenarios, and discuss its various potential advantages.
Efficacy of a 3D Electrospun Synthetic Polymer Matrix on Hard-to-Heal Wounds
Authors:   Cardiothoracic & Endovascular Medicine, Bond Clinic PA, Winter Haven, Florida, Lambert C. Jake , Aviles Frank ,   Lymphatic and Wound Healing Services, Hyperbaric Physicians of Georgia, Cumming, Georgia, Eckert Kristen A. ,   Strategic Solutions, Inc., Bozeman, Montana, Garoufalis Matthew ,   4Professional Foot Care Specialists, PC, Chicago, Illinois, Schilling Richard A. ,   ABC Podiatry, Columbus, Ohio
Published: January 2024

Introduction: The aim of this study was to evaluate the efficacy of a 3D electrospun synthetic polymer matrix (3DESPM) on hard-to-heal wounds. Materials and Methods: This prospective case series took place at four sites. The primary endpoints were the percentage area reduction (PAR) in wound area at four and eight weeks. Secondary endpoints included time to heal (Kaplan-Meier analysis) and the proportion of healed wounds at 12 weeks. After applying 3DESPM, the physician applied sterile saline, as appropriate, to adhere the matrix to the wound bed and facilitate the polymer degradation process. A nonadherent dressing, a secondary dressing, and additional bandages (as needed) were then applied. The physician left the product on the wound until complete degradation was observed, as appropriate, and reapplied, as appropriate. Combination advanced therapies were applied, per physician discretion. Results: Thirty-eight patients (mean age: 64.3 years [SD: 17.6]) with 50 wounds (35 chronic, 70%) participated. The mean number of comorbidities per patient was 4.4 (2.3). All wounds received 3DESPM; 12 wounds (24%) received combination therapies; and 38 wounds (76%) completed the study. The mean (SD) PAR at four and eight weeks was 67.6% (38%) and 80% (35%), respectively. Thirty-three wounds (66%) healed at 12 weeks. The Kaplan-Meier mean time to heal for all wounds was 49.0 days (95% confidence interval: 41.3–56.7). Conclusions: In a complex patient population with severe comorbidities and heterogeneous wounds, 3DESPM appeared to accelerate the stalled healing process to contribute to wound closure. Further investigation of 3DESPM on a larger patient population and in a controlled setting is pending.
Muḥammad b. Khalaf Wakīʿ (m. 306/918), ou le désamour de Bagdad
Authors: Tillier Mathieu
Published: January 2024

This article provides an overview of the life and work of a historian largely overlooked by contemporary historiography, Muhammad b. Khalaf al-Ḍabbī, known as Wakīʿ (d. 306/918). This Baghdadian scholar and qadi authored several works in various fields, only one of which has come down to us in a single manuscript: the Akhbār al-quḍāt, one of the earliest sources on the history of Islamic judgeship. Wakīʿ received fierce criticism from his fellow scholars and their successors, before most of his work fell into oblivion. After tracing his training and career, I examine the author’s views about Baghdad. The marginal role he assigns to the Abbasid capital, in connection with the miḥna of the mid-third/ninth century, suggests that this period of inquisition traumatized historians who came from scholarly backgrounds, and had a profound impact on Islamic historiography.
What is the “physics” of the process of spasm of large arteries and atherosclerosis?
Authors:   Russian New University (RosNOU), 22 Radio str., Moscow,, Vladimir Ivanovich Ermoshkin
Published: January 2024

It is known that a person’s life expectancy depends on the degree of acquired atherosclerosis. But doctors do not yet know what the mechanism of atherosclerosis development is. Researchers refer to 30 risk factors, mainly related to the lifestyle of a modern person. But how do these risk factors turn normal elastic artery walls into harder and plaque-covered walls by the age of 30-40? That’s the question.
Left atrial non-Hodgkin’s lymphoma: A case report
Authors:   Department of Ultrasound, First Affiliated Hospital of Chengdu Medical College, Chengdu, Si Chuan, China,, Liu Jian
Published: January 2024

Primary cardiac lymphoma is an extremely rare cardiac tumor. Herein, we report a 67-year-old male patient who sought medical attention for recurrent heart palpitations and left atrial mass on echocardiography. The left atrial space-occupying lesion was surgically removed. The final pathological diagnosis was cardiac non-Hodgkin’s lymphoma, and the patient’s heart palpitations and discomfort significantly improved after surgery.
Acute ST-segment elevation myocardial infarction after intravenous thrombolysis in acute cerebral infarction: A case report and Literature review
Authors:   Department of Cardiology, Yijishan Hospital of Wannan Medical College, Wuhu, China, Yuan Chi
Published: January 2024

Acute ischemic stroke is a common emergency in neurology. At present, there are two common treatment methods, intravenous thrombolysis and transcatheter mechanical thrombectomy. However, there are few reports of acute myocardial infarction after intravenous thrombolysis with Alteplase(rt-PA). However, the pathogenesis of acute myocardial infarction after thrombolysis and its relevance to thrombolytic therapy are still unclear. This article combines case reports to illustrate its possible pathogenesis and review of related literature.
Skull metastasis from follicular thyroid cancer
Authors:   Department of Surgery, General Hospital of Polygyros – Chalkidiki, Greece Hippokratous 5, Polygyros Chalkidiki 63100, Greece, Lalountas Miltiadis
Published: January 2024

Differentiated thyroid cancers have indolent clinical course and good prognosis with an approximate 85–90% 10-year survival rate. Distant metastases from follicular thyroid cancer are uncommon but are one of the main causes of cancer-specific mortatily. Mainly involve the lung, bone, and brain. Bone metastasis most commonly occurs in the vertebrae, costas and hip bones. Metastasis of a follicular thyroid carcinoma to the skull is very rare and only a small number of reports are found in the literature. We present a case of solitary lytic skull metastasis of a follicular thyroid cancer in a 79-year-old woman. The patient presented with a painless mass on the right side of the head. Physical examination showed a large, palpable, immobile and hard tumor. CT scan showed thyroid enlargement along with neck lympadenopathy and a lesion with an osteolytic component in the right parietal area. The patient was euthyroid and we performed an initial biopsy excision. The histopathological examination revealed a well-differentiated follicular thyroid cancer metastasis. After that a total thyroidectomy was subsequently performed. The patient refused the craniectomy and was given thyroid-stimulating hormone (TSH) suppression therapy followed by whole body iodine-131 (I131) internal radiation. She gave up on therapy and died 20 months after the initial surgery. Management of metastatic thyroid cancer, requires a multidisciplinary approach and multimodality treatment. Distant metastases should be surgically removed whenever possible, providing the best chance to prolong patient survival. Radiotherapy should be reserved for inoperable and residual tumor cases.
Rapidly developing colitis induced by combination therapy of lenvatinib and anti-PD-1 antibody in the treatment of hepatocellular carcinoma
Authors:   Department of Pharmacy, Huashan Hospital, Fudan University, 12 Middle Urumqi Road, Shanghai 200040, China, Wang Bei , Ma Jinyuan
Published: January 2024

Although diarrhea caused by immune checkpoint inhibitors (ICIs) or tyrosine kinase inhibitor (TKI) are common, server colitis caused by tyrosine kinase inhibitor (TKI) combined with anti-PD-1 has not been paid attention to. The combination of lenvatinib and anti-PD-1 antibody has been applied for an effort for HCC treatment. We reported two cases of initially lenvatinib induced mild diarrhea while fast developed into rather severe colitis after the first dose of anti-PD-1. We speculated that lenvatinib may be a trigger of anti-PD-1 related colitis through mediating the degradation of PD-L1 in colon tissue to make disturbance of immunity homeostasis and increasing the percentage of activated CD8+ T cells infiltration. Prevention and treatment of these related adverse effect were put forward.
Analisis Dampak Alih Fungsi Lahan Perkebunan Menjadi Lapangan di Desa Sirnasari
Authors: Lestari Shila Dwi , Syahrani Silmi , Gunadi Feri Ari , Kamila Hikma , MD Azka Taqiyya
Published: January 2024

Alih fungsi lahan perkebunan menjadi lapangan merupakan fenomena yang semakin umum terjadi di berbagai wilayah. Perubahan ini sering dipicu oleh berbagai faktor seperti pertumbuhan populasi, kurangnya lahan kosong untuk memenuhi kebutuhan masyarakat sekitar. Alih fungsi lahan perkebunan menjadi lapangan memiliki dampak ekonomi, sosial dan lingkungan. Penelitian ini dilakukan di Kp. Cangkerewang RT 001 RW 009, Desa Sirnasari, Kecamatan Sariwangi dengan tujuan untuk mengkaji dampak dari berbagai aspek terkait alih fungsi lahan perkebunan menjadi lapangan. Penelitian ini menggunakan metode deskriptif kualitatif dengan menggambarkan atau mendeskripsikan dampak dari alih fungsi lahan perkebunan terhadap kondisi ekonomi, sosial dan lingkungan. Data yang digunakan adalah data primer yang diperoleh melalui wawancara dengan 2 responden dan data sekunder yang diperoleh dari hasil studi pustaka, jurnal dan internet. Hasil penelitian menunjukkan bahwa terjadinya pengalihan fungsi lahan perkebunan menjadi lapangan ini memiliki dampak positif dan negatif. Dampak positif dari alih fungsi lahan ini antara lain meningkatkan ketersediaan lahan untuk kebutuhan publik, juga dapat mendorong pertumbuhan ekonomi lokal. Hasil penelitian ini juga mengidentifikasi adanya dampak negatif terhadap lingkungan karena dapat berakibat pada berkurangnya lahan perkebunan di wilayah tersebut.
Pemberdayaan Komunitas Ibu PKK Melalui Pelatihan Pengolahan Susu Kedelai Sari Telang Sebagai Pendamping Air Susu Ibu (MP-ASI) Sebagai Upaya Pencegahan Stunting Di Desa Truko, Kabupaten Kendal
Authors: Alarif Bimantoro , Widyastuti Dini , Tamalia Santi Risqi , Shofa Dina Nala , Nuranita Lili , Adistiya Tiara Nur , Nasyarah Aspira Sajidatun , Nur’aini Lathifah , Ardyanto Galuh , Rusli Yeni , Mustofa Muhamad Jazuli , Hapsari Dinda , Salam Abdul
Published: January 2024

Salah satu permasalahan yang ada di Desa Truko ialah gangguan pertumbuhan pada anak atau sering disebut dengan stunting. Di Desa Truko sendiri terdapat 39 orang anak yang terindikasi stunting, kemudian pemerintah setempat mengintervensi dua anak yang terindikasi stunting dengan memberikan asupan makanan selama 90 hari. Oleh karena itu, untuk mencegah stunting yang berkelanjutan pada anak di Desa Truko, mahasiswa KKN memiliki rancangan ide pembuatan susu kedelai dengan mengkombinasikan bahan dasar Bunga Telang. Metode yang digunakan pada penelitian ini adalah Workshop yaitu sosialisasi dan pelatihan, sosialisasi terdiri dari pemaparan materi mengenai kandungan serta manfaat bunga telang kemudian pelatihan pembuatan olahan bunga telang menjadi agar-agar dan susu kedelai. Sasaran kegiatan ini adalah komunitas ibu PKK, kader posyandu, ibu hamil, serta ibu yang mempunyai anak balita di Desa Truko dengan jumlah 30 peserta. Kegiatan pengabdian masyarakat melalui pemberdayaan pelatihan pengolahan susu kedelai sari telang dilakukan dengan beberapa tahapan, diantaranya pemaparan materi tentang pengetahuan pentingnya pencegahan stunting melalui asupan gizi dari olahan susu kedelai, dan bunga telang serta pengenalan telang, manfaat telang, kandungan telang, dan olahan makanan yang dapat dicampurkan dengan bunga telang. Dengan demikian pelatihan pemanfaatan kedelai dan bunga telang dilakukan untuk menghasilkan inovasi produk susu kedelai sari telang sebagai pendamping air susu ibu dalam rangka upaya pencegahan stunting.
Oemah Oeyah: Rumah Inovasi Garam Sebagai Bentuk Community Based Resources Management di Kalurahan Purwodadi, Gunungkidul
Authors: Alfarizi M. Zaky , Salsabila Sonia Nada , Rozaan Faiz Fadhilah Jalu , Rafeinia Dhara Cita , Yeza Adzkia
Published: January 2024

Sebagai salah satu kalurahan yang berbatasan langsung dengan Samudera Hindia, Kalurahan Purwodadi memiliki potensi pengembangan garam yang besar, Total produksi garam di Purwodadi mencapai angka 2,2 ton per triwulan keempat tahun 2022. Sifat garam sebagai produk inelastis sempurna menjadikan garam memiliki nilai permintaan yang stabil dan cenderung lebih tahan terhadap distraksi ekonomi. Penelitian ini berusaha untuk mendeskripsikan kegiatan yang dilakukan oleh tim PKM-PM Universitas Gadjah Mada dengan metode community based resources management melalui rumah inovasi garam “Oemah Oeyah” dengan Karang Taruna sebagai mitra. Sistematika alur Oemah Oeyah berupa Input, Proses (stakeholders mapping, expertise, dan role), serta output yang terbagi menjadi beberapa program yakni, sosialisasi kegiatan Oemah Oeyah kepada karang taruna Purwodadi, pembentukan pengurus Oemah Oeyah, studi banding Oemah Oeyah ke Kampung Garam Tlogopragoto, diskusi pemanfaatan kandungan garam, pelatihan marketing dan diversifikasi produk, pembentukan strategio produk, pertemuan inkubasi bisnis, sosialisasi promosi sosial media, lokakarya, dan pembuatan buku pedoman produksi garam dan tata kelola organisasi untuk Karang Taruna. Adapun hasil kegiatan adalah Karang Taruna menjadi lebih mengetahui proses produksi garam yang terstandarisasi, sistem penataan kelembagaan yang tertata, terbentuknya kolaborasi antar aktor pelaku usaha garam, serta terciptanya produk garam Oemah Oeyah yang siap jual dengan ekosistem bisnis yang lebih menjanjikan.
Peningkatkan Kinerja Publikasi Institusi Melalui Pengelolaan Jurnal Ilmiah Bereputasi
Authors: Setiawan Ahmad Ikhwan , Dewi Amina Sukma , Haryanto Budhi , Purwanto Djoko
Published: January 2024

Kepemilikan jurnal oleh fakultas atau program studi di suatu perguruan tinggi (PT) merupakan keunggulan bersaing institusi untuk meningkatkan kinerja publikasi PT dan mempercepat pencapaian fungsional (lektor kepala dan guru besar) bagi dosen di PT tersebut. Kegiatan pengabdian ini bertujuan agar setiap fakultas atau program studi mampu merancang dan mengembangkan jurnal bereputasi sebagai wadah publikasi. Terdapat dua tahap kegiatan yang dilakukan 1) Workshop Penulisan paper pada jurnal berkualitas dan 2) Workshop Pengelolaan Jurnal berkualitas. Pengabdian ini menyadarkan peserta untuk memahami kunci keberhasialn pengelolaan jurnal yaitu 1) komitmen pengelola, 2) dukungan mitra bestari dan 3) kerjasama dengan asosiasi. Fakultas Ekonomi dan Bisnis,  Universitas Sebelas Maret (FEB UNS) bersama dengan Ikatan Sarjana Ekonomi Indonesia (ISEI) Surakarta telah merancang dan mengembangkan jurnal untuk mempublikasikan jurnal yang secara bertahap dapat ditingkatkan kuliatasnya dan terindeks SINTA dan SCOPUS.
Pelatihan Desain Menggunakan Canva Di Pusat Layanan Disabilitas Dinas Sosial Kota Denpasar
Authors: Darma Yasa Ngakan Putu , Putra Yasa I Wayan Adi , Anggara I Gede Adi Sudi
Published: January 2024

Dinas Sosial merupakan salah satu instansi pemerintah yang memiliki peranan dalam meningkatkan kualitas kesejahteraan sosial perorangan, kelompok maupun masyarakat. Dinas sosial Kota Denpasar khususnya merupakan perangkat daerah yang mempunyai tugas serta fungsi membantu Walikota dalam penyelenggaraan pembangunan di bidang kesejahteraan sosial. Pengembangan bidang kesejahteraan sosial merupakan bagian dari pembangunan nasional serta memegang peranan penting untuk mewujudkan manusia Indonesia seutuhnya. Oleh karena itu pembangunan bidang kesejahteraan sosial, diarahkan untuk memberikan kontribusi yang nyata dan terukur. Pelatihan dalam pengabdian ini bertujuan meningkatkan kesejahteraan masyarakat yang kurang beruntung atau disebut Pemerlu Pelayanan Kesejahteraan Sosial (PPKS) / Penyandang Masalah Kesejahteraan Sosial (PMKS). Berikut adalah langkah-langkah yang dilakukan untuk menangani Pemerlu Pelayanan Kesejahteraan Sosial (PPKS) yaitu dengan melakukan pembinaan maupun pemberdayaan. Langkah tersebut mampu mendorong kemandirian serta menumbuhkan kepercayaan diri sehinga mendapatkan pekerjaan atau membuka usaha mandiri. Untuk mewujudkan langkah-langkah tersebut, Kampus INSTIKI bekerja sama dengan Dinas Sosial Kota Denpasar melaksanakan pendampingan kepada anak-anak berkebutuhan khusus. Pendampingan ini dilaksanakan secara langsung di kantor Dinas Sosial Kota Denpasar dengan memberikan materi pembelajaran yaitu desain menggunakan canva web. Luaran dari pengabdian ini adalah pelatihan desain menggunakan canva web dan artikel yang diunggah pada jurnal pengabdian sebagai bagian dari tri dharma perguruan tinggi. Hasil dari pelatihan ini menunjukkan bahwa anak-anak didik mampu menerapkan desain yang diberikan oleh pengajar.
Verification of the Analytical Solution and Numerical Simulation for Tension - Pressure
Authors: Kravarikova Helena
Published: January 2024

The proposed constructions have to meet their use in terms of shape, dimensions and above all, strength. Parts of the structure are loaded by external forces. The load on the structure is examined in all parts and directions. Parts of the structure are stressed by a combination of basic types of stress. One of the basic types of stress is pull or pressure. The investigation of the part of the structure under tensile-compression stress is important because of the deformation, stability and strength of the structure as a whole. Analytical solution, classical experiment or modelling FEM can be used to predict the stress of structural parts. Currently, the most preferred solution is FEM numerical simulation. Numerical simulation has a more purposeful use in the solution of structural stability. The article contains the solution, tensile stresses for a steel rod, numerical simulation using the FEM method in the ANSYS program and analytically.
PAPEL DA MOLÉCULA PDL-1 NO PROGNÓSTICO DO CARCINOMA DE CÉLULAS ESCAMOSAS ORAL: UMA REVISÃO DE LITERATURA
Authors: Bezerra Nicole Maria Mota , Rebouças Antonia Natasha Tavares Cavalcante , Silva Júlia Emilly dos Santos , Paula Dayrine de
Published: January 2024

O sistema imunológico humano utiliza como um dos seus mecanismos de regulação o checkpoint imunológico. O PD-1 é um dos receptores de membrana, do checkpoint imunológico, em Linfócitos T que liga-se a proteína PDL-1. Alguns tipos de cânceres, como o de cabeça e pescoço, levam a superexpressao da PDL-1. E, por isso, algumas imunoterapias que são drogas inibidoras possuem PD-1/PDL-1 como alvo. O objetivo do presente trabalho foi realizar uma revisão de literatura avaliando o papel damolécula PDL-1 no prognóstico de carcinoma de células escamosas oral. A busca de dados foi realizada na plataforma Pubmed, utilizando os descritores “Oral Squamous Cell Carcinoma” AND “CTLA4” AND “PD1”, sem restrições. Assim, foram encontrados 25artigos que após uma leitura rigorosa de títulos e resumos, foram selecionados 7 para constituir a presente revisão. Em síntese, foi observado que a imunoterapia com drogas inibitórias de PD-1/PDL-1 é eficaz e mostra-se um assunto atual. Entretanto, devido a toxidade elevada, tem limitações para uso em certos pacientes. É observado também que algumas características patológicas como tumor visível, inflamação, reações de células grandes e queratinas acelulares diminuíram de forma significativa. É importante pontuar que alguns tumores, como os positivos para HPV obtiveram maior expressão de PD-1 do que os tumores negativos para HPV. Foi mostrado que reduz também a progressão maligna e portanto, é um importante tratamento a ser estudado.
REDUÇÃO DE FATORES PRÓ-INFLAMATÓRIOS ATRAVÉS DA UTILIZAÇÃO DA CURCUMINA NA DOENÇA PERIODONTAL: UMA REVISÃO DA LITERATURA
Authors: Rebouças Antonia Natasha Tavares Cavalcante , Bezerra Nicole Maria Mota , Silva Júlia Emilly Dos Santos , Paula Dayrine Silveira de
Published: January 2024

Os distúrbios periodontais abrangem um amplo espectro de problemas inflamatórios que danificam os componentes de suporte dos dentes (ou seja, gengiva, osso e ligamento periodontal). Atualmente, muitas abordagens preventivas e de tratamento seconcentram principalmente no gerenciamento do biofilme, em vez de controlar os mediadores inflamatórios do hospedeiro responsáveis pelo dano tecidual nas estruturas periodontais. O objetivo do presente trabalho é avaliar os efeitos terapêuticos do uso da cúrcuma na doença periodontal. A busca de dados foi realizada na plataforma PubMed utilizando os descritores“Curcumin” e “Periodontal Diseases” e “Periodontics” escritos em inglês, sem restrição de tempo, foram encontrados 105 artigos que após leitura rigorosa de títulos e de resumos foram selecionados 7 para síntese do trabalho. A curcumina é uma substância extraída na raiz de cúrcuma ou açafrão, diversas pesquisas demonstraram um amplo espectro de efeitos terapêuticos, como anti-inflamatório, antioxidante e antibacteriano, essas propriedades podem ser úteis no tratamento de doenças periodontais inflamatórias. Uma vez que, a curcumina reduz níveis de mediadores inflamatórios de IL-6 IL-1b e TNF-a, além de reduzir o edema e melhorar a cicatrização. Em suma, o manejo da doença periodontal de forma terapêutica e preventiva utilizando a cúrcuma de forma adjuvante oferece melhor controle do biofilme e de mediadores inflamatórios que estão presentes na patogênese da doença. Mais estudos são necessários para determinar o efeito da curcumina em pacientes com doença periodontal.
RESUMOS DA XXVI JAO DA UNIVERSIDADE DE FORTALEZA (JAO)
Authors: XXVI JAO - UNIFOR RESUMOS DA
Published: January 2024

Não aplicável.
Pengembangan Model Manajemen Bank Sampah untuk Optimalisasi Pengelolaan Sampah di Desa Kedungmulyo
Authors: Utomo Sri Wahyu , Wahyuningsih Sri , Harumi Whisonya , Aris Ahmad Farkhan
Published: January 2024

Bank sampah adalah solusi untuk mengurangi dampak pencemaran. Bank sampah sebagai tempat untuk memanfaatkan sampah organik maupun anorganik. Penelitian ini dilakukan di Desa Kedungmulyo, Kecamatan Bangilan, Kabupaten Tuban, dengan sampel sebanyak 10 rumah. Penelitian ini bertujuan untuk membangun sistem manajemen. Metode yang digunakan dalam pelaksanaan kegiatan ini adalah sosialisasi dengan memberikan surat undangan kepada sampel rumah tangga, selanjutnya adalah pengumpulan sampah secara langsung. Sampah organik dimanfaatkan sebagai pupuk dengan penambahan EM4, sedangkan sampah anorganik dijual untuk memperoleh modal awal dan dimanfaatkan untuk menanam benih sayuran. Benih tanaman digunakan sebagai alat tukar bank sampah. Rekomendasi yang dapat diberikan oleh penulis adalah tindak lanjut bank sampah di Desa Kedungmulyo dengan membentuk pengurus bank sampah.
Inovasi Peningkatan Pendapatan Petani Bunga Melati melalui Diversifikasi Produk: Studi Kasus Dusun Bunalas
Authors: Musyafak Musyafak , Windari Rusmilawati
Published: January 2024

Kabupaten Bangkalan adalah salah satu daerah yang berada di Provinsi Jawa Timur yang memiliki keunggulan sebagai daerah berpotensial di sektor pertanian, khususnya komoditas bunga melati. Kabupaten Bangkalan mempunyai areal lahan bunga melati seluas 50 hektar. Kecamatan yang memiliki jumlah petani bunga melati dan luas lahan terbesar yaitu Kecamatan Burneh, tepatnya di Dusun Bunalas Desa Tunjung. Namun, terdapat permasalahan yang menyebabkan petani bunga melati tidak dapat meningkatkan pendapatannya yaitu kurangnya diversifikasi bunga melati dan tidak mengetahui cara mengolah bunga melati sehingga tidak dapat meningkatkan nilai tambah. Tujuan dari pengabdian ini yaitu memberikan pengetahuan agar petani bunga melati dapat melakukan diversifikasi atau pengolahan bunga melati menjadi lilin aromaterapi. Kegiatan ini dilakukan dengan 10 petani yang ikut dalam sosialisasi dan pelatihan pembuatan lilin aromaterapi. Dalam perkembangannya terdapat 3 tahapan dalam keberlanjutan pengabdian ini yaitu tahap jangka pendek, menengah dan panjang dengan maksud agar menghasilkan produk lilin aromaterapi yang dapat dipasarkan.
Problem Solving dalam Menemukan Konsep Matriks
Authors: Adityawan Tofan , Najih Ainun , Sastria Yayon Adi Galung
Published: January 2024

Pemecahan masalah secara umum diterima sebagai alat untuk memajukan kemampuan berpikir. Pemecahan masalah juga dianggap sebagai tulang punggung metodologi dalam mendekati muatan matematika karena hal ini membutuhkan dan membantu mengembangkan keterampilan menganalisis, pemahaman, penalaran dan aplikasi. Oleh karena itulah pemecahan masalah diharapkan hadir dalam setiap pembelajaran matematika.  Menurut NCTM (2000) standar pemecahan masalah yang harus dicapai oleh siswa adalah (1) Membangun pengetahuan matematika baru melalui pemecahan masalah, (2) Menyelesaikan masalah yang muncul dalam matematika dan konsteks lain, (3) Menerapkan dan menggunakan berbagai macam strategi yang sesuai untuk menyelesaikan permasalahan, (4) Memonitor dan merefleksikan proses pemecahan masalah matematika. Sehingga guru mempunyai peran memilih masalah yang bermanfaat, memilih masalah dengan bijaksana, dan menggunakannya serta mengadaptasi masalah dari materi pembelajaran. Guru memainkan peran penting dalam pengembangan disposisi pemecahan masalah siswa dengan menciptakan dan memelihara lingkungan kelas, di mana siswa didorong untuk mengeksplorasi, mengambil risiko, kegagalan dan keberhasilan, dan mempertanyakan satu sama lain. Dalam lingkungan yang mendukung tersebut, siswa mengembangkan kepercayaan diri dalam kemampuan mereka dan kesediaan untuk melakukan dan mengeksplorasi masalah, dan mereka akan lebih cenderung mengajukan masalah dan terus berlanjut dengan masalah yang menantang. Pemecah masalah yang baik adalah mereka yang menyadari apa yang mereka lakukan dan sering melakukan pemantauan, atau menilai diri sendiri, kemajuan mereka atau menyesuaikan strategi mereka saat mereka menghadapi dan memecahkan masalah. Sebagai guru memelihara lingkungan atau suasana sangatlah penting, dimana pengembangan pemahaman secara konsisten dipantau melalui refleksi, siswa lebih cenderung untuk belajar untuk mengambil tanggung jawab untuk merenungkan pekerjaan mereka dan membuat penyesuaian yang diperlukan ketika memecahkan masalah, salah satunya saat melakukan pemecahan masalah pada materi matriks.
ЖАЛПЫ ОРТО БИЛИМ БЕРҮҮЧҮ МЕКТЕПТЕРДЕ ХИМИЯ ПРЕДМЕТИНЕН 8-9-КЛАССТАР ҮЧҮН ОКУУ КИТЕПТЕРИНИН КЭЭ БИР ТЕМАЛАРЫНА СУНУШТАР
Authors: Абдулазизов Тилебалды , Кайратбек кызы Диана , Гуламова Таттыбүбү
Published: January 2024

Маанилүүлүк. 8-класста “Валенттүүлүк” деген темада кычкылтектин үч валенттүү бирикмелери (H3O+ жана ис газы СО) бар экендигин ушул темага жазууну сунуштайбыз. “Кислоталар” деген темада H3PO2 бир негиздүү, H3PO3 эки негиздүү экендигин белгилеп өтүү зарыл. Суудагы эритмеде суутек иону (Н+) түрүндө жазуунун ордуна гидроксония ионун (H3O+) жазууну жана “Элементтердин кычкылдануу даражалары” деген темага атомдордун кычкылдануу даражаларынын мааниси валенттүүлүккө дал келбеген бирикмелердин химиялык формулаларын жазууну сунуштайбыз. Жогорку окуу жайлар үчүн жазылган окуу китептерде кычкылдануу даражаларынын мааниси валенттүүлүккө дал келбеген бирикмелер боюнча маалыматтар жазылган. Жогорудагы темаларга сунушталган пикирлер жалпы билим берүүчү мекемелерде химия предмети жазылган окуу китептеринде болсо, жогорку окуу жайда “жалпы химия” жана “органикалык эмес химия” предметтерди окуганда студенттерде кайчы пикир жаралбайт.
МОЛДО НИЯЗДЫН САНАТТАРЫ ЖАНА АНДАГЫ ГЕОГРАФИЯЛЫК МААЛЫМАТТАР
Authors: Эргашов Садирали , Колдошов Мисирали
Published: January 2024

Молдо Нияздын санат дигаристтарындагы адеп-ахлактык аң-сезимдин баалуулуктар тутумунун өзгөчөлүктөрү каралат. Аймактагы мурдагы реалдуулуктун азыркы кубулушу менен байланышын, Кыргызстан аймагында жаратылыш ресурсун пайдаланууну жаңы чарбалык өзгөчөлүктөрү аныкталат. Ал коомдук ишмердүүлүктүн тарыхый-географиялык, педагогикалык-социалдык формаларынын арасында алдыңкы орунду ээлеши керек. Чөлкөмдөгү табыгый-географиялык билим жана адамдын айланасындагы чарба жүргүзүү иш-аракеттерди окурмандар билим берүү менен байланыштырууга арекет кылышат. Ошондой эле практикада ийгиликтүү колдонуу зарылдыгы сунушталат. Келечекте Молдо Нияздын санаттарын улуттук нарктын негизинде жаштарга сиңдирип баруу зарыл.
САРКЕНТ МАМЛЕКЕТТИК ЖАРАТЫЛЫШ ПАРКЫНДА БАЙЫРЛАГАН ЧЫЧКАН СЫМАЛ КЕМИРҮҮЧҮЛӨРДҮН ТҮРДҮК КУРАМЫ ЖАНА САНДЫК БӨЛҮШТҮРҮЛҮШҮ
Authors: Абдыкааров Абдиманнап , Атабеков Усан , Курсанбекова Кылымбүбү
Published: January 2024

Маанилүүлүк. Бул макалада Саркент мамлекеттик жаратылыш паркында байырлаган чычкан сымал кемирүүчүлөрдүн 8 түрүнүн (Dryomys nitedula, Microtus arvalis, Ellobius tancrei, Apodemus sylvaticus, Mus musculus, Rattus turkestanicus, Rattus norvegicus, Alticola argentatus) 6 ландшафт (шагал таштуу тоо боорлору, арча токойлор, бадалдуу токойлор, табигый жээк экотондору, антропогендик селитебдик ландшафттар жана агроценоздор) боюнча сандык бөлүштүрүлүшүн изилдөө жыйынтыктары баяндалды. Изилдөө жыйынтыктары чычкан сымал кемирүүчүлөрдүн ичинен доминанттык орунду Apodemus sylvaticus (28,12±3,97%), ал эми субдоминанттык орунду Rattus turkestanicus (25,0±3,83%) жана Rattus norvegicus (15,62 ± 3,21) ээлегендиги тастыкталды. Ландшафттар боюнча кемирүүчүлөрдүн түрдүк курамы арча токойлорунда басымдуулук кылып, 6 түрдүн байырлагандыгы жана алардын пайыздык үлүшү 29,69±4,04 ди көрсөттү. Парктын аймагында байырлаган чыгыш сокур момолоюнун (Ellobius tancrei) тыгыздыгын аныктоонун жыйынтыгы орточо эсеп менен 1 га аянтка 28-30 особь туура келээрин көрсөттү. Бул түр негизинен парктын төмөнкү аймактарында гана катталды.