bluuebunny/crossref_metadata_2025 huggingface dataset:
Режимы роста пленок нитрида алюминия на гибридных подложках SiC/Si(111)
Authors: Корякин А.А. , Кукушкин С.А. , Осипов А.В. , Шарофидинов Ш.Ш.
Published: October 2021

The nucleation mechanism of aluminum nitride films grown by the method of hydride vapor phase epitaxy on hybrid substrates 3C-SiC/Si(111) is theoretically analyzed. The temperature regions and vapor pressure regions of components are determined in which the island growth mechanism and the layer-by-layer growth mechanism are realized. The theoretical conclusions are compared with the experimental data. The morphology of aluminum nitride film on 3C-SiC/Si(111) at the initial growth stage is investigated by the method of scanning electron microscopy. The methods of controlling the change of the growth mechanism from the island growth to the layer-by-layer growth are proposed.
К вопросу о влиянии неоднородного диэлектрического покрытия на характеристики металлической поверхности
Authors: Погосов В.В.
Published: October 2021

Within the framework of the quantum-statistical functional and the Ritz method, the
the problem of finding the surface energy per unit area and work function electrons of a
metal flat surface with a inhomogeneous dielectric coating, taken into account in the
approximation of a continuous medium. For a uniform coating, the calculated values are
insensitive to the selection one-parameter functions for an electronic profile, but
sensitive to the gradient series of kinetic energy non-interacting electrons. Calculations
are performed for Al, Na and the comparison with the calculations by the Kohn-Shem
method is made. Analytically the connection between the theory of the Ritz method for
inhomogeneous coatings and calculations by the Kohn-Shem method work function of
electrons for metal-dielectric nanosandwiches. As it turned out, the influence
inhomogeneous coating on the characteristics of the metal surface can be scaled down to
a uniform coverage case. The possibility of using the obtained results in various
experimental situations are discussed.
Variation in the rate of diagnosis of childhood acute lymphoblastic leukemia in about to the COVID-19 Pandemic: a single-center study
Authors: Kazancı Elif Güler , Üstündağ Yasemin , Güven Deniz
Published: October 2021

Background. Greaves delayed infection hypothesis states that acute lymphoblastic leukemia (ALL) in children develops in two critical steps, with the first step (first hit) occurring in utero and the second step (second hit) occurring in the postnatal period and involving leukemia-associated genetic changes, depending upon the timing of exposure to common childhood infections. In this study, we investigated whether isolation of children at home as part of the lockdown during the Coronavirus Disease 2019 (COVID-19) pandemic resulted in a reduction in the number of new childhood ALL cases by avoiding the second hit. Materials and metods. This retrospective study included all newly diagnosed pediatric ALL patients aged 1–18 years. The study periods were from 15 March 2020 to 31 December 2020 (COVID-19 lockdown period) and from 15 March 2019 to 31 December 2019 (control period). Results. Acute leukemia was diagnosed in 73 children between January 2019 and December 2020. Of these, there were 58 ALL cases and 15 acute myeloid leukemia cases. During the COVID-19 lockdown period, 14 of the children were diagnosed with ALL. In the control period, 21 children were diagnosed with ALL. No pediatric patients diagnosed with ALL in August, September, and October 2020. Conclusions. We observed a reduced incidence within the lockdown period, possibly related to the potential role of SARS-CoV-2 infection as a second hit in childhood ALL.
Evaluating the efficacy of preventive influence of the dietary supplement Vitaglucan with immunocorrective and antioxidant properties in children with frequent acute respiratory infections
Authors: Mitiuriaeva-Kornijko I.O. , Burlaka Ie.A. , Polukhina M.O.
Published: October 2021

Background. Acute respiratory infections (ARI) are one of the most common groups of diseases in pediatric practice. According to the latest statistics, 1/6 of the world’s population suffers from them in the inter-epidemic period. There is no specific prevention of ARI, which requires the search for effective non-toxic medicines of non-specific prevention, in particular those with immunocorrective and antioxidative effects. The purpose of the study was to evaluate the change in the number of ARI episodes in children administered Vitaglucan, a dietary supplement with immunocorrective properties, and to study the subjective indicators of the syrup intake satisfaction. Materials and methods. The study includes 943 children aged 3–18 years who had ≥ 6 episodes of ARI during the previous year (retrospective data from medical records). We have evaluated the change in the number of ARI episodes in children prescribed Vitaglucan, a syrup with immunocorrective properties containing β-glucan (from Pleurotus ostreatus) and sea buckthorn juice. Subjective indicators of syrup efficacy were assessed. Results. The results obtained indicate the presence of a pronounced preventive effect of the dietary supplement Vitaglucan on the occurrence of ARI in children both on the background of taking the syrup and during the epidemic period. Syrup tolerability, results of its administration were assessed as high, the parents also rated the effectiveness of the dietary supplement as high. Conclusions. Dietary supplement Vitaglucan can be included in the diet of children over 3 years of age as an additional source of β-glucan and biologically active substances of sea buckthorn.
Regulation of miRNA content. Part 3. Circadian mechanisms. Single nucleotide polymorphisms of microRNA genes
Authors: Abaturov A.E. , Babуch V.L.
Published: October 2021

The scientific review presents the process of regulation of miRNA content — the association of miRNA expression activity with circadian rhythms of organism functioning and the dependence on the presence of single nucleotide gene polymorphisms. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka. The article presents the characteristics of the molecular architecture of circadian clocks of mammals, which are due to the action of day and night, light and darkness. It is stated that the violation of circadian rhythms of the organism is associated with the development of obesity, diabetes, depression, cardiovascular pathology, and tumors. It is also known that the violation of the circadian rhythm of liver function leads to the development of metabolic disorders and, in particular, the emergence of non-alcoholic fatty liver disease, diabetes, and obesity. It is emphasized that microRNAs are factors that determine the functioning of circadian rhythm mechanisms, and the expression of some of them is highly dependent on the time of day. The article shows that to date, more than 240 single-nucleotide polymorphisms of genes and rare mutations in pri-, pre- and mature miRNA sequences have been identified. It is known that single nucleotide polymorphisms of genes of the first group (pri- and pre-microRNAs) interfere with the normal process of maturation of microRNAs. Single-nucleotide polymorphisms of genes of the second group (“seed” region) lead to disruption of the interaction of microRNAs with target mRNAs. An association between microRNA genetic polymorphisms and various human diseases, including diseases of the hepatobiliary system, has been established. Thus, the activity of miRNA expression determines the functioning of the mechanisms of the circadian rhythm of the mammalian organism, and the expression of some of them is highly dependent on the time of day. The normal process of maturation of miRNAs is hindered by single nucleotide polymorphisms of genes of the first group (pri- and pre-miRNAs). Single nucleotide polymorphisms of genes of the second group lead to disruption of interaction of miRNA with mRNA targets. Circadian rhythm disorders and genetic microRNA polymorphisms are associated with the development of various pathological conditions and human diseases, including diseases of the hepatobiliary system.
Brain Tumor Identification and Locating
Authors: Sriram Sanjeev
Published: October 2021

Abstract: Various poorer-grade glioblastoma subtypes related with outline attribute have been identified in a late research. poorer-grade glioblastoma can have symptoms ranging from slight seizures to extensive seizures, affecting the capability to talk or even lift your arms and legs. This poorer-grade glioblastoma is handled with a combination of surgery and examination by monitoring the tumor with brain MRI scans. The study of this project enabled us to build a completely self-working system for segmentation of tumor utilizing computer vision techniques, and deploying models that would allow high- quality LGG detection in the brain MRI would potentially be self-working to identify the genomic subtype of the tumor by quick and low-cost imaging. The methodology, procedures, pros and their boundaries and their future ultimatums are discussed in this project.
Advanced Machine Learning model for Health Monitoring in IoT System
Authors: Parbat Tanmayee Tushar
Published: October 2021

Abstract: Health issues are also concealed by a lack of health precautions on a daily basis. These issues frequently constitute a serious threat to public safety, which is frequently overlooked until it is too late. As a result, we have developed a set of principles to address and, to some extent, solve the issues outlined above. We continuously monitor the vital organs in our system; communicate data to cloud-based doctors, and alert patients to potential dangers. We designed an IoT system that connects several sensors to a microcomputer and sends collected data to a cloud server for Modified Stochastic Gradient Descent(SGD) Algorithm with a combination of deep learning. If the doctor suspects a health problem, he or she may issue a warning via our device after the examination is completed. Our proposed approach work Health Monitoring in IoT System Keywords: machine Learning, Health Monitoring, IoT System, Deep Learning
A note on Variance-Sum Third Order Slope Rotatable Designs
Authors: Shareef R. Md. Mastan
Published: October 2021

Abstract: Response Surface Methodology (RSM) is a collection of mathematical and statistical techniques useful for analyzing experiments where the yield is believed to be influenced by one or more controllable factors. Box and Hunter (1957) introduced rotatable designs in order to explore the response surfaces. The analogue of Box-Hunter rotatability criterion is a requirement that the variance of i yˆ(x)/ x be constant on circles (v=2), spheres (v=3) or hyperspheres (v 4) at the design origin. These estimates of the derivatives would then be equally reliable for all points (x , x ,...,x ) 1 2 v equidistant from the design origin. This property is called as slope rotatability (Hader and Park (1978)).Anjaneyulu et al (1995 &2000) introduced Third Order Slope Rotatable Designs. Anjaneyulu et al(2004) introduced and established that TOSRD(OAD) has the additional interesting property that the sum of the variance of estimates of slopes in all axial directions at any point is a function of the distance of the point from the design origin. In this paper we made an attempt to construct Variance-Sum Third Order Slope Rotatable in four levels. Keywords: Response Surface Methodology. Third Order Slope Rotatable Design; TOSRD (OAD), Variance-Sum Third Order Slope Rotatable Design.
How to Connect SensorTag and PC
Authors: Gupta Sudhanshu
Published: October 2021

Abstract: Connecting SensorTag to your PC is itself a difficult task. In this paper we will discuss how to connect SensorTag to Pc? Which version you should specifically download according to your windows requirement? What all we should download in CCS to connect to your SensorTag? Which project we should import to run your first program? Keywords: CCS, TI.
The herd immunity to SARS-CoV-2 among the population of the Nizhny Novgorod region amid the COVID-19 epidemic
Authors: Popova A. Yu. , Ezhlova E. B. , Melnikova A. A. , Smirnov V. S. , Lyalina L. V. , Efimov E. I. , Kucherenko N. S. , Zaitseva N. N. , Sadykova N. A. , Sarskov S. A. , Chekhova G. A. , Arbuzova T. V. , Vetrov V. V. , Totolian A. A.
Published: October 2021

The aim of the study was to assess the seroprevalence to the SARS-CoV-2 nucleocapsid in the population of the Nizhny Novgorod region against the background of COVID-19.Materials and methods. The work was carried out according to a unified methodology developed by Rospotrebnadzor with the participation of the St. Pasteur. The selection of volunteers for the study was carried out by the method of questioning and randomization. The exclusion criterion was active COVID-19 infection at the time of the survey. A total of 2829 volunteers were surveyed, divided into seven age groups. Venous blood samples were taken from all volunteers from EDTA vacutainers. In the blood plasma, the content of specific IgG to the SARS-CoV-2 nucleocapsid was determined by the enzyme immunoassay.Results. The population level of immunity to SARS-CoV-2 among the surveyed volunteers was 8,4% (95% CI 7,4–9,5). The largest proportion of seroprevalent persons was found among children aged 1–6 years — 15,9% (95% CI 8,2–26,7), the smallest in the group of volunteers aged 18–29 years — 6,0% (95% CI 3,8–8,9). During 3-stage serological monitoring, the proportion of seroprevalent volunteers increased to 22,5% (95% CI 20,3–24,9)%, or almost 2 times from the initial level (p<0,05). of the population of the Semenovsky district (22,7% (95% CI 10,9–41,8)), the smallest — in the city of Dzerzhinsk (2,4% (95% CI 0,5–7,1)%) Among convalescents after COVID-19, specific antibodies were detected in 47,2% (95% CI 30,5–69,6), which is 5,6 times higher than the average for the population. Among those who had verified contact with patients, specific IgG were detected in 17,6% (95% CI 12,9–23,5), which is 2,1 times higher than the average for the population. Among asymptomatic persons who had a positive PCR result, 53,3% (95% CI 30,5–86,6) were seropositive, which is 6,3 times higher than the average for the population. Of 225 seropositive people, 188 (88,4% (95% CI 76,6–101,6)) had the disease asymptomatic.Conclusion. The relatively low proportion of seroprevalent persons among the population may indicate a significant risk of further development of the epidemic process caused by COVID-19 in the territory of the Nizhny Novgorod region.
Hematological disorders in HIV-infected children on the background of antiretroviral therapy
Authors: Daminov T. A. , Tuychiev L. N. , Khudaykulova G. K. , Rakhmatullaeva Sh. B. , Muminva M. T.
Published: October 2021

Introduction. In most cases, HIV infection in children is accompanied by the development of anemia.Objective: to study the nature of the disturbance of the cellular composition of blood in HIV-infected children on the background of antiretroviral therapy.Materials and methods. In the period from September 2015 to January 2017, 124 patients aged from 0 to 18 years old were examined with a diagnosis of HIV infection at various stages of its development. In all patients in the peripheral blood, the hemoglobin concentration, the absolute number of red blood cells, leukocytes and their varieties in a blood volume unit were determined, the hematocrit value was calculated.Results and discussion. Against the background of ongoing antiretroviral therapy, the formation of hypochromic anemia is associated with a consistent decrease in hemoglobin concentration and the number of circulating red blood cells to 104,86±2,80 g/l and to 3,81–3,67×1012/l, which may be accompanied by a decrease in their content in each erythrocyte and the appearance of macrocytic erythroid forms in circulating blood. Leukopenia develops due to the formation of an absolute deficiency of circulating lymphocytes and neutrophilic granulocytes.Conclusion. The specific assessment of cytopenia depends on the type of primary damage to the blood cells, and the choice of specific treatment depends on the type of disorder. Therefore, timely correction of these disorders could possibly reduce the development of the immunodeficiency state.
Broadly neutralizing antibodies for the treatment of HIV infection
Authors: Glazkova D. V. , Bogoslovskaya E. V. , Shipulin G. A. , Yudin S. M.
Published: October 2021

Antibodies with neutralizing activity against a wide range of human immunodeficiency virus 1 subtypes (known as broadly neutralizing antibodies — bNAb) are of great interest as a therapeutic agent for the treatment of HIV infection, because they are able to provide natural protection against most HIV-1 strains. The review discusses the mechanisms of formation of bNAbs, their classification by binding to conservative regions of the envelope protein, as well as their intrinsic features. Description of the most promising bNAbs and their combinations is presented.In the last section the results of clinical trials of 3BNC117, VRC01 and 10-1074 bNAbs available to date are reviewed in detail. An important finding of these studies was that the introduction of a single antibody is followed by the appearance of resistant viral variants. The investigation of the only combination of 3BNC117 and 10-1074 completed so far indicates that combined therapy is more effective and allows to achieve long-term viral suppression in some patients. The promise of combined HIV immunotherapy is evidenced by the initiation of a large number of clinical trials evaluating the efficacy of two or more different bNAbs.
Amino acid substitutions in core and HBsAg regions of hepatitis B virus in patients with monoinfection and HBV/HIV-coinfection in the Republic of Guinea
Authors: Boumbaly S. , Serikova E. , Balde Th. A. L. , Ostankova Yu. V. , Schemelev A. N. , Valutite D. Е. , Zueva E. В. , Semenov A. V. , Totolian A. A.
Published: October 2021

The aim of this study was to characterize the genetic variants of HBV currently circulating in the Republic of Guinea, based on the nucleotide sequences of the complete virus genome, and to analyze clinically significant mutations in the Core and HBsAg regions during HBV monoinfection and HBV/HIV coinfection.Materials and methods. The study material was represented by 2616 blood serum samples collected from residents of the Republic of Guinea. The subjects were examined for the presence of HBV markers with a qualitative detection of HBsAg, HBs IgG, and HBCore IgG. HBV complete genome nucleotide sequences were obtained for 298 samples including HIV/HBV coinfected patients. Amplification and subsequent sequencing of HBV were performed using nested PCR with pair’s overlapping primers jointly flanking the complete HBV genome (S, P, C, X genes).Results. HBV serological markers were detected in 80.77% samples, while HBsAg was detected in 16.01% of the examined group. HBV DNA we detected in 22.36%. The prevalence of HBsAg-negative HBV in patients with HIV RNA is 45.16%, which is significantly higher than 6.07% found in the group without HIV infection. Phylogenetic analysis of HBV in the examined samples showed that HBV genotype E (75.5%) predominates in the group compared to HBV genotype D1 (9.39%), D2 (4.02%), D3 (6.37%), and A2 (4.7%). In the tested group, the variability of amino acids among the HBV samples was higher in the PreCore/Core region than in the PreS1/PreS2/S region. SHB mutations were detected in 83,89%, Core mutations in 94.29%, PreCore amino acid substitutions in 16.77% of the patients, respectively.The results obtained in this work demonstrate a high prevalence of HBV in the region and indicate the need for further largescale studies of HBV mutations in order to improve strategies for disease control and prevention in the Republic of Guinea.
Vortex Layer on the β-Plane in the Miles – Ribner Formulation. Pole on the Real Axis
Authors: Gnevyshev V. G. ,   Shirshov Institute of Oceanology, Russian Academy of Sciences, Moscow, Russia, Belonenko T. V. ,   Saint Petersburg State University, St. Petersburg, Russia
Published: October 2021

Purpose. The problem of a non-zonal vortex layer on the β-plane in the Miles – Ribner formulation is considered. It is known that in the absence of the β-effect, the vortex layer has no neutral eigenmodes, and the available two ones (varicose and sinusoidal) are unstable. Initially, generalization of the problem to the β-plane concerned only the zonal case. The problem for a non-zonal vortex layer is examined for the first time in the paper. It is known that in the WKB approximation for the linear wave disturbances (regardless of whether a zonal or non-zonal background flow is considered), there is an adiabatic invariant in the form of the law of the enstrophy flow (vorticity) conservation. For the zonal vortex layer, the enstrophy conservation law also holds, and no vorticity exchange occurs between the waves and the flow in the zonal case. The non-zonal vortex layer has qualitatively different features; particularly, it does not retain enstrophy. Thus, as a result, there appears a new class of solutions which can be interpreted as pure radiation of the Rossby waves by a non-zonal flow. Generalizing the vortex layer problem on the β-plane to the non-zonal case constitutes the basic aim of the present study. Methods and Results. A new class of linear stationary wave solutions, namely the Rossby waves, is found. It is shown a non-zonal flow can be directed in one way, whereas the stationary wave disturbances can move in the opposite (contrary) direction. The coexistence of such solutions for the shear non-zonal flow and stationary wave disturbances takes place due to the influence of the external force and mathematically comes from a non-self-adjoint character of the linear operator for a non-zonal background flow. Conclusion. There exists a new class of solutions that can be interpreted as pure radiation of the Rossby waves by a non-zonal flow. There is no such solution for a zonal flow. It is just non-zoning that gives the effect of pure radiation and corresponds to the classical definition of radiation. This approach makes it possible to eliminate inconsistency in terminology, when instabilities are mistakenly called radiation, and radiation – pure radiation.
Correlations between the Parameters of the Light Volume Scattering Functions in the Mediterranean Sea Surface Waters
Authors: Mankovsky V. I. ,   Marine Hydrophysical Institute, Russian Academy of Sciences, Sevastopol, Russian Federation, Mankovskaya E. V. ,   Marine Hydrophysical Institute, Russian Academy of Sciences, Sevastopol, Russian Federation
Published: October 2021

Purpose. The aim of the work is to study relationships between the parameters of the light volume scattering functions based on the data of their measurements in the Mediterranean Sea surface waters. Methods and Results. The data of measurements of the light volume scattering functions in the water samples taken in a few regions of the southern Mediterranean Sea, namely from the Strait of Gibraltar to the Levant Sea, as well as in the central part of the Aegean Sea and near the Dardanelles Strait (May, 1998) were used. The following parameters of the volume scattering functions were calculated: total scattering coefficient, and asymmetry and variation coefficients. The maximum and minimum values of the scattering coefficient were 0.21 and 0.09 m–1, respectively; and those for the asymmetry coefficient – 77.8 and 33.9. The variation coefficient of the angle scattering coefficients changed within 35– 79 %, its maximum and minimum values fell on the angles 7.5° and 162.5°, respectively. Obtained were the relations between the variation coefficient and the scattering angle, the asymmetry coefficient and the scattering coefficient, and the angle scattering coefficients and the total scattering coefficient. All of them possess high (more than 0.9) correlation coefficients. The coefficient value (51.7 %) at the angle 2° does not correspond to general relation of the variation coefficient to the scattering angle. This fact is explained by different contributions of coarse and fine suspended matter to the light volume scattering function. At the angle 2°, the main contribution is made by a coarse (organic) suspended matter, whereas at the angles exceeding 7.5° – by a fine (mineral) suspension. Conclusions. The values of the variation coefficient of the angle scattering coefficient at the angles equal to 2° and exceeding 7.5° demonstrate variability of the coarse and fine suspended matter in the Mediterranean Sea, respectively. The equation for the relation between the asymmetry coefficient of the light volume scattering functions and the total scattering coefficient obtained for the Mediterranean Sea waters is close to the analogous one obtained for the Atlantic Ocean tropical waters. The angle 3.5° is optimal for determining the total scattering coefficient using the angle scattering coefficient for the Mediterranean Sea functions.
Quantitative Approach to Studying Film Pollution of the Sea Surface Using Satellite Imagery
Authors: Zamshin V. V. ,   AEROCOSMOS Research Institute for Aerospace Monitoring, Moscow, Russia, Matrosova E. R. ,   AEROCOSMOS Research Institute for Aerospace Monitoring, Moscow, Russia, Khodaeva V. N. ,   AEROCOSMOS Research Institute for Aerospace Monitoring, Moscow, Russia, Chvertkova O. I. Chvertkova ,   AEROCOSMOS Research Institute for Aerospace Monitoring, Moscow, Russia
Published: October 2021

Purpose. Numerous studies of various film pollutions (oil spills, surfactants etc.) are performed by means of satellite monitoring of seas and oceans. However, the problem of formal ranking the water areas of the regions under study by frequency and intensity of pollution is still unsolved. The conditions and periodicity of satellite survey can differ greatly depending on the monitoring region that determines both spatial variability of the probability of film pollution detection and the need to take this feature into consideration. Here we attempt to develop a quantitative approach to studying the sea surface film pollutions based on processing of large volumes of satellite optical and radar imagery. Methods and Results. The concept “index of sea surface exposure to film pollutions”, dfpMON, and the method for calculating its quantitative value on a regular spatial grid are proposed. The value of dfpMON is defined as a ratio of the pollution area observed at the site to the area of the analyzed resolution elements (where detection of film pollution is theoretically possible). Within the framework of this approach, the already existing methods for analyzing the results of long-term satellite seawater pollution monitoring were improved due to taking into account the meteorological conditions and the spatial distribution of the observation amount. Having been applied, the proposed approach permitted to study spatial distribution of the non-biogenic film pollutions in the northern part of the Black Sea; they were detected resulting from interpretation of 4428 satellite images obtained in 2019 by the Landsat-8, Sentinel-2A/B and Sentinel-1A/B satellites (2499 cases of pollution processed). The average value of the dfpMON index was 0.012 %. Three regions, where the dfpMON values exceeded the average one by more than 30 times were identified. Conclusions. The example of a site in the northern Black Sea has shown the possibility of obtaining representative information products of satellite oceanography, which quantitatively characterize spatial variability of the sea surface film pollution recorded during the long-term episodes of space monitoring.
Exploring the Relationship between Socioemotional Skills and Decision-Making Styles in Health Students
Authors: Silva Cândida G. , Gordo Sara , Rodrigues Ana Cristina , Henriques Carolina , Rosa Marlene
Published: October 2021

Higher education in health study programs is particularly focused on the development of technical skills, despite there being a consensus on the importance of training students regarding socioemotional and life skills. The aim of this study was to characterize and explore correlations between socioemotional skills and decision-making styles in undergraduate health students. Undergraduate students (18–25 years old) were recruited at a School of Health Sciences in Portugal. Participants were characterized in terms of sociodemographic data, socioemotional skills (Study on Social and Emotional Skills questionnaire) and decision-making styles (Melbourne Decision Making questionnaire). Descriptive statistics and correlations between questionnaires´ subscales were calculated. Students presented higher scores in tolerance (34.8±3.4), cooperation (34.7±2.4), empathy (31.1±3.2), vigilance (16.0±1.9), and procrastination (9.9±2.1). Assertiveness presented negative correlations with buck-passing (rho=-0.43, p<0.01) and procrastination (rho=-0.38, p<0.01) and positive correlation with vigilance (rho=0.22, p=0.03). Students demonstrated higher values in empathy, cooperation, and tolerance skills, meaning they tend to be kind and care for others’ well-being. Vigilance style is related to assertiveness characterizing hard working leaders able to pay attention to others’ needs. Training that involves socioemotional skills might be crucial for the style of decision-making in future health professionals.
The Code-Switching Phenomenon during Oral Presentations among the Business Programme Students
Authors: Subon Frankie , Tarmim Siti Sarah Mohd
Published: October 2021

In Malaysia, English as a second language is used as a medium of instruction in most institutions of higher learning. Although it is compulsory to use English as a medium of instruction for all academic programmes, code-switching is still prevalent in the classroom for instance during an oral presentation. This phenomenon is also common among the students in the bachelor’s degree in International Business (BIB) at a private university in Selangor, Malaysia that became the context of this study. Hence, this research aimed to explore the BIB students’ perceptions on the utilisation of code-switching during oral presentations, and to identify the frequency of its usage in their speech. The participants of this study were 203 students from the Faculty of Business Management and Professional Studies (FBMP) of a private university in Selangor, Malaysia, who are currently doing their bachelor’s degree in International Business. The research instrument employed was a questionnaire that was accessible through a google form link by all the 203 students. Descriptive statistics were run to analyse the data collected. The findings of this study revealed that the students perceived positively the use of code-switching during oral presentations. Majority of them agreed that they code-switched to overcome their lack of proficiency in English such as limited vocabulary, and to ease their oral presentations. Most of the students admitted they frequently code-switched during oral presentations. From these findings, important implications and recommendations for future research were elucidated.
The Crimean-Congo haemorrhagic fever tick vector Hyalomma marginatum in south of France: Modelling its distribution and determination of factors influencing its establishment in a newly invaded area
Authors: Bah Madiou Thierno , Grobois Vladimir , Stachurski Frédéric , munoz facundo , Duhayon Maxime , rakotoarivony Ignace , Appelgren Anaïs , Calloix Clément , Zayas Liz Noguera , Mouillaud Théo , Andary Charlotte , Lancelot Renaud , Huber Karine , Garros Claire , Leblond Agnes , vial laurence
Published: October 2021

For the first time we built a correlative model for predicting the
distribution of H. marginatum, one of the main vector of Crimean-Congo
Haemorrhagic fever virus (CCHFV), at high resolution in a recently
colonized area, namely south of France. Field tick collections were
conducted on horses from 2016 to 2021 in 14 French southern departments,
which resulted in a first map of H. marginatum on the national
territory. Such updated presence/absence data, as well as the mean
number of H. marginatum per examined animal (mean parasitic load) as a
proxy of the tick abundance, were correlated to multiple parameters that
described the climate and habitats characterizing each collection site,
as well as movements of horses as a possible source of tick diffusion
and new establishment. Our model highlighted the importance of warm
temperatures all along the year, as well as dry conditions during summer
and moderate annual humidity for the establishment of H. marginatum. A
predominance of open natural habitats in the environment was also
identified as a supporting factor, in opposition to artificial and humid
habitats that were determined as unsuitable. Based on this model, we
predicted the current suitable areas for the establishment of the tick
H. marginatum in South of France, with a relatively good accuracy using
internal and external validation methods. Concerning tick abundance,
some correlative relationships were similar than in the occurrence model
but the type of horse movements were also pointed out as an important
factor explaining the mean parasitic load, leading to differential
exposure to ticks. The limitations of estimating and modelling H.
marginatum abundance in a correlative model are discussed.
Fixed-time projective synchronization of delayed memristive neural networks via aperiodically intermittent switching control
Authors: Pu Hao , Li Fenjun
Published: October 2021

In this paper, the fixed-time projective synchronization issue for a
class of delayed memristive neural networks is studied via aperiodically
intermittent switching control. Firstly, according to the existing
aperiodically intermittent switching strategy, a novel theorem for
aperiodically intermittent switching fixed-time stability is proposed
and proved through mathematical induction. Subsequently, an
aperiodically intermittent switching controller is designed to reach
fixed-time projective synchronization for drive-response systems. The
power exponent is a function of error system state rather than one or
two fixed constants. With the help of the extended differential
inclusion framework, the inequality technique and the analysis method,
some novel sufficient conditions are derived to ensure fixed-time
projective synchronization for the considered systems. The settling time
is closely related to the number of neurons and the maximum ratio of the
rest width to the aperiodic time span, but independent of the initial
value conditions. Furthermore, the fixed-time complete synchronization,
fixed-time anti-synchronization and fixed-time stability obtained are
special cases of the main theorem. Meanwhile, the conclusions of this
paper improve some previous relevant works. Finally, a numerical example
is given to verify the effectiveness and feasibility of the obtained
results
Role of AScorbic acid Infusion in critically ill patients with Transfusion Related Acute Lung Injury (ASTRALI)
Authors: kassem Amira , Ahmed Islam , Omran Gamal , Megahed Mohamed , Habib Tamer
Published: October 2021

Introduction: In critically ill patients, Transfusion Related Acute Lung
Injury (TRALI) remains the leading cause of transfusion-related
fatalities in critical care setting and associated with inflammation and
oxidative stress state. Recent research raised the potential efficacy of
high dose intravenous ascorbic acid in critically ill patients.
Objective: The aim of this trial was to investigate the effect of high
dose intravenous ascorbic acid (VC) as a targeted therapy for TRALI in
terms of serum proinflammatory (interleukin-8, interleukin-1β,
C-reactive protein), anti-inflammatory (interleukin-10), oxidative
stress (superoxide dismutase, malondialdehyde) markers, and plasma VC
levels. Secondary outcomes were oxygenation (PaO2/FiO2 ratio),
vasopressor use, duration of mechanical ventilation, ICU length of stay,
7-days mortality and 28-days mortality. Methods: Eighty critically ill
patients with TRALI (n=80) were randomized to receive 2.5gm/6hr
intravenous vitamin C for 96 hours (ASTRALI group) or placebo. Patients
were followed-up to measure the outcomes initially (T0) and at the end
of treatment (T96). Results: When compared to control group, ASTRALI
group at T96, showed significantly higher median of interleukin-10 (31.6
± 25.8 Vs. 17.7 ± 12.0 pg/mL, p<0.0001) levels and superoxide
dismutase (12876 ± 4627 U/L Vs. 5895 ± 6632 U/L, p<0.0001)
activities, lower median C-reactive protein (76 ± 50 Vs. 89 ± 56 mg/L,
p=0.033), interleukin-8 (11.8 ± 7.3, 35.5 ± 19.8 pg/mL,
p<0.0001), and malondialdehyde (0.197 ± 0.034 Vs. 0.234 ±
0.074 µM/L, p=0.002) levels. Conclusion: High dose ascorbic acid was
associated with significantly reduced oxidative stress, reduced
pro-inflammatory markers except IL-1β, elevated anti-inflammatory
marker, and elevated plasma VC levels
ON ABBREVIATION IN GERMAN TEXTS BY M. LOMONOSOV
Authors: FILIPPOV ANDREI K. , FILIPPOV KONSTANTIN A.
Published: October 2021

The article studies cases of abbreviation in German texts by M. Lomonosov, including initials, etiquette title names, and contractions of dates, city names, measures and currency. The authors propose a lexicographic description model for presenting contracted words and phrases in the upcoming dictionary of Lomonosov’s German vocabulary. The study also focuses on methodological issues such as borders of Lomonosov’s German idiolect.
Imprisonment during COVID-19 in Brazil: A Brief Review on the Prison Situation during the Pandemic
Authors: Maduro Flávio Mirza
Published: October 2021

This mini-review aims to reflect upon the conditions of penitentiaries in Brazil during times of the pandemic; it also brings to discussion the recent decision by the Supreme Court of Brazil which allowed for certain detainees to carry out their sentences under house arrest; in addition, it aims to discuss how the judges on lower courts have decided in light of the aforementioned Supreme Court ruling. By outlining the conditions of imprisonment that can be observed in the jailing system, the authors seek to critically reflect upon the role of justice in the society during times of hardship. The authors begin by tracing a historical background in a concise way, in order to elucidate how situations of illnesses and bereavement have developed during the years. After that, the authors compare judicial rulings involving the current prison status quo. To conclude, the authors seek to add to the debate joining the voices who cry out for more assertive measures in the preservation of life and health of detainees and prison workers.
How can Clinical Research Trials Conducted in Developing Countries Minimize Exploitation?
Authors: Mukherjee Gia
Published: October 2021

Western scholars, pharmaceutical companies, and academic institutions are and have been conducting research in developing countries for many years. These locations boast substantial cost savings, expedited timelines, and little to no regulatory oversight, making them attractive to developed-world researchers. Residents of these communities are impoverished, often illiterate, unemployed, and with untreated health conditions. Because established ethical protocols for international research are often compromised or misconstrued by researchers and/or their sponsors, these individuals are left vulnerable to exploitation and abuse. In this paper, I explore how current utilization of ethical guidelines is enabling exploitation. I identify ethical questions regarding subject recruitment, informed consent, standard of care, and the post-trial obligations of researchers. I then examine specific situations in which exploitation occurred because of drug, vaccine, or clinical trials. I conclude by offering recommendations to create a more streamlined approach to international research that takes into account the experiences and needs of vulnerable populations. This approach helps ensure that participants are fully involved in the ethical approval process; able to choose whether or not to participate without any undue influence or pressure; treated with the standard of care best suited to their context and surroundings; and reasonably given access to any interventions proven effective during the course of the trial.. A respect for beneficence, justice, and self-autonomy should guide researchers’ interactions with subjects before, during, and after the trial.
Comunicação suplementar e alternativa na população idosa e sua relação com as atividades de vida diária:
Authors: Assef Carolina Avance , Garros Danielle dos Santos Cutrim , Oliveira Jáima Pinheiro de , Rocha Aila Narene Dahwache Criado
Published: October 2021

Introdução: A população brasileira vem mantendo tendência de envelhecimento, resultando em alterações nos aspectos físicos e cognitivos do indivíduo. Algumas dessas alterações podem diminuir a perda da oralidade e levar a dificuldade de interação do indivíduo com o coletivo. Objetivo: Buscamos identificar de que maneira a Comunicação Suplementar e Alternativa (CSA) vem sendo relacionada com o público idoso em produções científicas e como objetivo específico, buscou-se relações entre o uso de recursos de CSA e as atividades de vida diária (AVD) nesta população. Método: O levantamento de artigos foi realizado em quatro bases de dados (Scielo, BDTD, BIREME e PubMed). Foram incluídos somente estudos que apresentavam intervenções com o uso de CSA que envolvessem a população idosa e as AVD. A qualidade metodológica das investigações foi avaliada por meio do check-list PRISMA, sendo registrado no PROSPERO-International Prospective Register of Systematic Reviews e para análise dos dados, foi utilizado o software Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires (IRaMuTeQ®). Resultados: Ao final das buscas foram obtidos um total de três artigos para compor o corpus de análise da revisão e todos foram avaliados com alta qualidade metodológica. As intervenções utilizadas nos estudos foram: confecções de álbuns e pranchas de CSA e livros de memória. Conclusão: Ao final da revisão ficou evidenciado que a CSA teve um impacto significativo para diferentes sujeitos, com diferentes intervenções que compuseram os estudos aqui apresentados.
Potencial evocado auditivo Mismatch Negativity em músicos adultos
Authors: Nascimento Lissandro Werlang do , Schwade Laura Flach , Didoné Dayane Domeneghini , Sleifer Pricila
Published: October 2021

Introdução: Mismatch Negativity (MMN) é um exame objetivo que não depende da realização de tarefas nem da atenção do sujeito. Tem sido utilizado para estudar o processamento auditivo relacionado à detecção automática de mudanças auditivas. Objetivo: Analisar latências e amplitudes do MMN em músicos adultos e comparar os resultados com um grupo controle de não músicos normouvintes. Método: Estudo transversal e comparativo. A amostra foi composta por 69 sujeitos, 40 sujeitos não músicos (grupo controle) e 29 sujeitos músicos (grupo estudo) todos com no mínimo três anos de experiência musical e idades superiores a 18 anos. Todos realizaram avaliação auditiva periférica e o MMN. Resultados: A média das latências e amplitudes do grupo controle foram, respectivamente, 173,61ms (±49.80) e 4,25µV (±3.60) e do grupo estudo foram, respectivamente, 144,23ms (±17.58) e 5,12µV (±2.73). Houve diferença estatisticamente significante entre os grupos por orelha (p<0,05), sendo a média das latências e amplitudes do grupo estudo de 140,08ms na orelha direita e 148,37ms na orelha esquerda, e 4,83µV na orelha direita e 5,41µV na orelha esquerda. Conclusão: O grupo de músicos apresentou melhores resultados, como menor latência e maior amplitude do MMN, evidenciando melhor processamento do estímulo acústico em nível central.
Desafios e impactos da atuação de fonoaudiólogos recém-formados no Espírito Santo durante a pandemia de COVID-19
Authors: Depolli Gabriel Trevizani , Brozzi Jéssica Nascimento , Alves Trixy Cristina Niemeyer Vilela
Published: October 2021

Introdução: Os fonoaudiólogos recém-formados podem estar passando por um momento único para sua atuação por causa da pandemia de COVID-19. Além do aprendizado da graduação, há as Resoluções do Conselho Federal de Fonoaudiologia, que têm alertado e auxiliado os profissionais nessa prática. Objetivos: verificar como fonoaudiólogos recém-formados atuam durante a pandemia de COVID-19, quais os desafios da graduação que podem refletir nessa atuação e conhecimentos sobre Resoluções do Conselho Federal de Fonoaudiologia (CFFa). Métodos: estudo observacional e transversal. Aplicou-se um questionário em graduados em Fonoaudiologia dos últimos 24 meses por uma instituição do Espírito Santo, apresentando os dados de forma descritiva. Resultados: entrevistou-se 32 fonoaudiólogos, 93,7% mulheres, média de 25 anos. Destes, 81,2% exerciam a profissão durante a pandemia, a maioria de maneira presencial, porém, houve redução do salário para ⅓. Em média 40% alegaram que a graduação ajudou na preparação para o atendimento de casos COVID-19, mas apenas 28% para telefonoaudiologia. A Resolução do CFFa mais citada foi sobre a telefonoaudiologia, por 81%. A atuação fonoaudiológica em casos de COVID-19 foi classificada por 75% como “Desafiadora”. Conclusão: a maioria dos fonoaudiólogos exerciam a profissão presencialmente, mas houve desemprego e redução do salário pela pandemia. Conheciam as Resoluções do CFFa, com destaque para a Resolução n. 580. Não houve consenso quanto à contribuição da graduação no atendimento desses casos, com desafios quanto a telefonoaudiologia e a urgência/emergência, que têm sido enfrentados pelos egressos, podendo impactar negativamente na vida profissional.
Efeitos perceptivo-auditivos de um treinamento de comunicação oral em locutores de uma rádio universitária
Authors: Batista Denis de Jesus , Conceição Aline Santos da
Published: October 2021

Introdução: os estudantes dos cursos de comunicação veem nas rádios universitárias a oportunidade do desenvolvimento das competências necessárias para o mercado de trabalho. Objetivo: descrever os efeitos perceptivo-auditivos de um treinamento de comunicação oral em locutores de uma rádio universitária. Método: aplicou-se o Programa de Desenvolvimento da Expressividade para Comunicação Oral em oito locutores. Ocorreram oito encontros de duas horas, cada. Coletou-se no primeiro e último encontro, o material para avaliação perceptivo-auditiva em que os participantes liam um texto informativo. As amostras foram aleatorizadas e dicotomizadas em Leitura A e Leitura B. Dois locutores tiveram as suas leituras duplicadas para análise da confiabilidade interna. Três fonoaudiólogas realizaram análise deste material sem conhecer o período ao qual elas pertenciam. Considerou-se apenas o julgamento daquela que mostrou maior coeficiência interna. Resultados: dos oito pares de leituras avaliados, seis foram considerados diferentes após o treinamento. Desses seis pares diferentes, quatro foram melhores após a intervenção. A associação da voz, fala e interpretação apontou-se como razão da escolha em três dessas leituras sendo a mudança mais evidente, a dicção. Os valores das notas das leituras após o treinamento mostraram-se superiores. As vozes com desvio leve tiveram uma discreta redução. A frequência vocal permaneceu inadequada, diferente dos demais recursos vocais que mostraram singela melhora: intensidade, velocidade de fala, pausas, modulação e ênfases. Conclusão: as notas das leituras, a qualidade vocal e alguns recursos vocais, exceto a frequência da fala, mostraram discreta evolução ao final do treinamento.