bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Enoxaparin Effectiveness Based on COVID-19 Severity: A Study in a Secondary Hospital in Bandung, Indonesia
Authors: Suprapti Budi , Debora Liana , Kusumawati Dewi , Dery PS Arina , T Gabriella Nathasya , Arini Mustika Novi , Aryanti Lusiana Dwi
Published: September 2022

Li Coagulopathy is a common predictor of mortality in COVID-19. Meanwhile, enoxaparin is an anticoagulant with anti-inflammatory, endothelial protection, and viral antagonist properties. Therefore, thromboprophylaxis with enoxaparin in COVID-19 is common in clinical settings. This study aims to assess enoxaparin's efficacy across different severity levels by examining its effect on primary outcomes comprising Length of stay (LOS), invasive mechanical ventilation, and mortality as well as secondary in the form of D-dimer, platelets, C-reactive protein (CRP), Neutrophil Lymphocyte Ratio (NLR), and Absolute Lymphocyte Count (ALC). During hospitalization, 269 patients received enoxaparin across varying severity levels comprising mild, moderate, and severe, while the Wilcoxon test was used to analyze the efficacy in each group. Additionally, the differences in patient characteristic profiles across the severity levels were determined using the Kruskal-Wallis test. The increase in mortality rate and the need for mechanical ventilation were directly proportional to the level of severity. D-dimer decreased from 1308.87 ng/ml to 979.83 ng/ml (p=<0,001) as well as from 1758.41 ng/ml to 1510.68 ng/ml (p=<0,001) in the mild and moderate levels respectively. The platelet increased from 225.65 to 369.39 x103/µl (p=<0,001) in mild and 256.77 to 398.97 x103/µl (p=<0,001) in moderate. Moreover, CRP improved in both mild 52.62 to 49.58 mg/l (p=0.031) and moderate 92.99 to 42.66 mg/l, (p=<0,001). Based on the results, enoxaparin effectively improves D-dimer, platelet, and CRP levels in mild and moderate but not in severe conditions, however, no effect was found on LOS, NLR, and ALC.
THE RELATIONSHIP BETWEEN NATIONAL CULTURE AND INNOVATIVE ENTREPRENEURIAL ORIENTATION: AN ANALYSIS FOR THE SOUTHEAST EUROPEAN COUNTRIES
Authors: Amidžić Renata , Leković Bojan , Fazekaš Tibor , Matić Milenko
Published: September 2022

This paper aims to examine the relationship between entrepreneurial attitudes of national culture and innovative entrepreneurial orientation (IEO). The empirical research employs multiple linear regression models, utilizing data obtained from the Global Entrepreneurship Monitor. For the purpose of empirical research, we selected samples of early-stage entrepreneurs incorporated in Bosnia & Herzegovina, Bulgaria, Croatia, Greece, and Slovenia. The main findings highlight a significant relationship between national cultural dimensions and innovation, while absorbing the knowledge value and information through media resources equally positively related to IEO, as well as the presence of high status disparity negatively related to IEO. The results can be explained by the specific entrepreneurial context of the SEE region. We also point out recommendations for future research.
EFFECTS OF ROTATION ON UNSTEADY FLUID FLOW AND FORCED CONVECTION IN THE ROTATING CURVED SQUARE DUCT WITH A SMALL CURVATURE
Authors: Hasan Mohammad Sanjeed , Chanda Ratan Kumar , Mondal Rabindra Nath , Lorenzini Giulio
Published: September 2022

In recent years, the analysis of flow disposition in a curved duct (CD) has greatly attracted researchers because it is broadly used in engineering devices. In the present paper, unsteady flow characteristics of energy transfer (HT) in a rotating curved square duct (CSD) have been presented with the aid of spectral method. The key purpose of this study is to explore rotational effects and heat transfer (HT) of the duct. For this purpose, time-evolution calculation is performed over the Taylor number (-1500 ≤ Tr ≤ 1500) and other parameters are fixed; e.g., Dean number (Dn = 1000), Curvature (δ = 0.015) and Prandtl number (Pr = 7.0, for water). Firstly, time-dependent behavior is accomplished for both clockwise and anticlockwise rotations. It is found that the flow instabilities are certainly governed by the change of Tr that has been justified by sketching phase spaces (PS). To observe the flow features, velocities including axial flow (AF), secondary flow (SF) and temperature profiles are disclosed for both rotations; and it is elucidated that 2- to 6-vortex solutions are generated for physically realizable solutions. Axial flow (AF) shows that two maximum-velocity regimes are produced which induces secondary flow (SF), and, consequently, a strong bonding between the AF and SF has been built up. It is observed that as the rotation is increased, the fluid is mixed considerably which boosts HT in the fluid. Finally, an assessment between the numerical and experimental data has been given, and a good agreement is observed.
APPLICATION POSSIBILITIES OF THE S960 STEEL IN UNDERWATER WELDED STRUCTURES
Authors: Tomków Jacek , Landowski Michał , Rogalski Grzegorz
Published: September 2022

In this paper, the application possibilities of the ultra-high strength (UHSS) Domex 960 steel in the underwater welded structures are analyzed. In the research, the investigated material has been tested in bead-on-plate wet welding conditions with the usage of different heat input values, namely 0.63 kJ/mm, 0.72 kJ/mm and 0.93 kJ/mm. Specimens were performed by the manual metal arc (MMA) welding method with the usage of rutile covered electrodes. Firstly, the nondestructive visual testing (VT) was carried out. In the next step, the metallographic macro- and microscopic tests were performed. Finally, the hardness of the weld metal and heat-affected zone (HAZ) was measured by the Vickers HV10 method. The performed experiments allow the statement that the Domex 960 steel could be welded in a water environment. It also showed that increasing heat input leads to decreasing the hardness in HAZ by 30 HV10. It may result in decreasing the susceptibility to cold cracking during butt- and filet welding in the water environment.
ON CLASSICAL WEAKLY PRIME SUBMODULES
Authors: Jamali Marziye , Jahani-Nezhad Reza
Published: September 2022

The aim of this paper is to introduce the concept of classical weakly prime submodules which is the generalization of the notion of weakly classical prime submodules to modules over arbitrary noncommutative rings. We study some properties of classical weakly prime submodules and investigate their structure in different classes of modules. Also, the structure of such submodules of modules over duo rings is completely described. We investigate some properties of classical weakly prime submodules of multiplication modules.
EXISTENCE AND UNIQUENESS OF SOLUTIONS FOR FRACTIONAL RELAXATION INTEGRO-DIFFERENTIAL EQUATIONS WITH BOUNDARY CONDITIONS
Authors: Lachouri Adel , Ardjouni Abdelouaheb , Djoudi Ahcene
Published: September 2022

The aim of this paper is to study the existence and uniqueness of solutions for nonlinear fractional relaxation integro-differential equations with boundary conditions. Some results about the existence and uniqueness of solutions are established by using the Banach contraction mapping principle and the Schauder fixed point theorem. An example is provided which illustrates the theoretical results.
NEW HERMITE-HADAMARD TYPE INEQUALITIES FOR $k$-$\beta $-CONVEX FUNCTIONS VIA GENERALIZED $k$-FRACTIONAL CONFORMABLE INTEGRAL OPERATORS
Authors: Lakhal Fahim , Badreddine Meftah
Published: September 2022

In this paper, we introduce a new concept $k$-$\beta $-convex functions and establish some new Hermite-Hadamard type inequalities for functions whose derivative modulus is $k$-$\beta $-convex via $k$-fractional conformable integral operators.
STEPANOV $\rho$-ALMOST PERIODIC FUNCTIONS IN GENERAL METRIC
Authors: Kostić Marko
Published: September 2022

In this paper, we analyze various classes of multi-dimensional Stepanov $\rho$-almost periodic functions in general metric. The main structural properties for the introduced classes of Stepanov almost periodic type functions are established. We also provide an illustrative application to the abstract degenerate semilinear fractional differential equations.
ON CUBIC (\alpha, \beta)-METRICS IN FINSLER GEOMETRY
Authors: Tondro Vishkaei Hosein , Tayebi Akbar
Published: September 2022

In this paper, we study the class of  cubic (\alpha, \beta)-metrics.  We show that every  weakly Landsberg cubic (\alpha, \beta)-metric has vanishing S-curvature. Using it, we prove that  cubic (\alpha, \beta)-metric is a weakly Landsberg metric if and only if it is a Berwald metric. This yields an extension of the  Matsumoto's result for Landsberg cubic metric.
VALIDNOST I POUZDANOST TESTA ZA PROCENU VREMENA REAKCIJE I BRZINE KRETANJA U ODBRAMBENOM KOŠARKAŠKOM STAVU
Authors: Vučković Igor , Gadžić Aleksandar , Sekulić Željko , Marković Saša
Published: September 2022

The aim of the present study was to examine the content validity and reliability of the newly developed Reaction Time and Defensive Slide Test (RTADST). Thirty-six female basketball players were recruited from three professional State Basketball league of Bosnia and Herzegovina clubs (age: 18.81 ± 2.58 years) who completed three separate trials of the RTADST with each trial consisting of fast shuffling movements left and right.  Each athlete performed the test 3 times in one day, and repeated testing was conducted the following day at evening basketball sessions. The RTADST relative reliability was evaluated by Cronbach’s alpha and ICC. Cronbach’s alpha coefficient was 0.81 which indicates good reliability. When recommendations from Bucheit et al. (2011) were taken into account, the value of ICC <0.69 indicated poor reliability. Absolute reliability of RTADST was assessed by CV, and its value was 5.3%, which is somewhat above the 5%, or the limit of acceptable reliability. Parameters of relative and absolute reliability after the exclusion of the first trial (familiarization with the test task), were more acceptable. Cronbach’s alpha coefficient was 0.90 and ICC = 0.82 compared to the one from all three trials. Considering absolute reliability, it could be concluded that the test is reliable since the CV value is below 5% (3.9%). Reliability between two days was assessed by ICC, and its value was 0.74, which confirms good reliability. Finally, the RTADST can be considered as a valid test that discriminates female basketball perimeter players and post players in reaction time and basketball defensive slide speed, while conditioning programs for the development of these abilities need to be carried out with a tool such is RTADST for the initial and final evaluation of these abilities.
BUILDING THE EUROPEAN MECHANISM FOR COMBATING HUMAN TRAFFICKING - A SYSTEM APPROACH
Authors: Đukić Anđelija R. , Andrejić Marko D.
Published: September 2022

The paper deals with combating human trafficking in the European area, while respecting the dialectical unity of theory and practice, applying the principles and logic of a system approach. The European mechanism for combating human trafficking, as a regional instrument, was created out of a need to combat human trafficking in an organized and multidisciplinary manner, which has become a serious problem in Europe. Building an effective, comprehensive and multidisciplinary mechanism is based on the greater application of the scientific approach, the harmonization of legal systems and concerted action of states, thereby achieving a synergistic effect. The European mechanism is seen as a complex, open, dynamic and stochastic organizational system, incorporating all European countries (except Russia) as components. Its functioning has achieved a more balanced approach of European countries to the problem and a more coherent operation of national mechanisms. The poly-centricity of the system originated as a consequence of the simultaneous action of the three governing units (the Council of Europe, the European Union, and the OSCE) on national mechanisms, and their lack of coordination complicates the position of the national mechanisms.
COMPARATIVE ANALYSIS OF ENVIRONMENTAL ATTITUDES OF YOUTH FROM EU MEMBER AND CANDIDATE STATES: CASE STUDY CENTRAL AND EASTERN EUROPE
Authors: Voza Danijela , Milošević Isidora , Vuković Milovan
Published: September 2022

Worldwide, great efforts are being made in order to establish sustainable development at all levels. European Union (EU) member states are obliged to meet the requirements in the area of environmental protection. In this paper, the authors conducted a comparative study of environmental attitudes among young people from both EU transition countries and EU candidate countries. The objective was to determine the differences in environmental attitudes, environmental awareness and self-efficacy of the youth from these two groups of countries and the EU environmental policy implementation level. Results indicated that the influence of EU membership exists when it comes to the environmental attitudes of youth from the analyzed countries. Average values showed the unsatisfactory situation regarding environmental awareness and self-efficacy of respondents. In order to define the relations among environmental attitudes, self-efficacy and environmental awareness, a structural model was created. This analysis showed that these three components work the same way in both groups of countries.
TOURISM-LED ECONOMIC GROWTH HYPOTHESIS - AN EMPIRICAL INVESTIGATION FOR SERBIA
Authors: Hristov Stančić Branislava , Đorđević Aleksandar , Kovačević Igor , Zečević Bojan
Published: September 2022

As it is commonly believed that tourism contributes positively to economic growth, many developing countries rely on tourism in their efforts to enhance their economic conditions. Serbia has also given priority to the development of tourism industry as a part of its economic growth strategy. In this paper we analyze the long-term effects of tourism on the economic growth of Serbia. More specifically, the tourism-led economic growth (TLEG) hypothesis is tested, which implies that tourism is a trigger of Serbian economic growth. This study investigates the causal relations between tourism growth and economic expansion for the Serbian economy by using cointegration analysis. The obtained results show that the hypothesis of tourism-led economic growth in the Serbian economy is confirmed.
Didática da religião
Authors: Escudero Jaime Caiceo , Vizcarra Alicia Allendes
Published: September 2022

A didática da religião é apresentada com ênfase na formação religiosa escolar, a fim de alcançar o discernimento espiritual religioso, para que o aluno dê sentido à sua vida; este fato é importante de ser abordado devido à secularização existente. É uma pesquisa-ação que utiliza os elementos próprios de planejamento do colégio Santa Isabel de Hungria com análise documental. A satisfação dos alunos tem sido detectada considerando que o religioso alia seu desenvolvimento evolutivo, psicológico e integral na sua formação de valores, no fundo, para encontrar um sentido para sua existência.
The Elon Musk effect: How community initiative spending impacts earned social media valuation
Authors: Akpan Mfon
Published: September 2022

This research study measures Uber’s community support initiatives’ return on investment (ROI). The company examined is Uber Technologies Inc. (Uber), which donates time and resources to support communities in need after natural disasters or lack social support. This study will take a quantitative approach by measuring the value of Uber’s community support initiatives’ earned media. The research will use a case study analysis to investigate how companies like Uber generate and assess the ROI of their social enterprise investments. This research is timely as it speaks to the current discourse on practical ways for businesses to create social impact and how to measure that impact. In addition, the research will use a combination of primary and secondary sources. This study will collect primary data through social media, and the secondary data will come from media valuation indices and sentiment analysis. The findings of this study will have implications for both Uber and other companies that engage in community support initiatives. For Uber, this study will provide insights into how the company can optimize its community support initiatives to generate the most significant ROI. For other companies, this study will serve as a case study for effectively measuring the ROI of community support initiatives.
Responsibility towards the Void
Authors: Mike Croft
Published: September 2022

The question of responsibility is explored through drawing, specifically relating to a so-termed void space that ranges over a builder's yard and its immediate environment. The research is formatted as dated journal entries to show its chronological development, with the proviso that later stages may eclipse earlier stages, depending on their relevance. This looping, as it were, mimics the fact that the void space is best defined by the occasional circling of swifts, an observation that becomes a metaphor for how to try to articulate the space pictorially. Responsibility is referenced through theories of each of Levinas, Lacan and Foucault in relation to the Other, the latter of which is taken as the theoretical equivalent of void, but no less concerning responsibility. The author has drawn the site in such terms as locate the void in both the space that the site defines and a gap in the drawing process. This artistic effort is analogous demonstration of responsibility to that which is suggested by the theory. Responsibility is considered from the perspective of the personal and individual, automatically present in artistic commitment, in this case finding some explanation in theoretical thinking of the abstract notion of Other. The formatting of the process of attending to this theme and motif as research leads to a situation where drawing, as such, is but the predominantly visual tool alongside art writing, academic research, and graphic layout that provides live links to video clips and two explanatory texts.
Feeding substrate selection is not affected by the soil and environment temperature during the foraging of Constrictotermes cyphergaster
Authors: Oliveira Mário Herculano de , Rolim Maria do Socorro Lacerda , Lira Derick , Bezerra-Gusmão Maria Avany
Published: September 2022

Termites are known as wood consumers, although some species eat other substrates. Assessing resource selection is important to understanding their biology. The present study provides information on the foraging behavior of Constrictotermes cyphergaster (Blattaria, Termitidae) in a dry forest area of Caatinga in Brazil. We aimed to verify the frequency of resource exploitation by termites as a function of environmental and soil temperatures. We found no significant differences in resource exploitation as a function of temperature, which is interesting because this variable is often reported as modulating foraging activity in some other termite species. This species forages on open trails at high temperatures in the Brazilian semi-arid zone. Environmental changes may affect the dynamics of their behavior and, consequently, the ecosystem, since C. cyphergaster influences the carbon cycle and can modify the soil. Our study provides a basis for future research intending to understand the adaptations of this termite to live in the drylands.
Evaluation of the toxicity, cytotoxicity and antibacterial activity of Tibouchina papyrus (Pohl) Toledo (Melastomataceae)
Authors: Da Cruz Danielle Coelho , Severo Menezes Antônio Carlos , Sabbag Cunha Gracielle Oliveira
Published: September 2022

The objective of this research was to perform a preliminary phytochemical study and investigate the toxicity, cytotoxicity and antibacterial activity of the species Tibouchina papyrus (Melastomataceae). The toxicity test was performed with the extracts against Artemia salina. The cytotoxic study was also performed against the following cell lines: promyelocytic leukemia (HL60), human colon carcinoma (HCT-116), breast carcinoma (MCF-7), prostate carcinoma (PC3), astrocytoma (SNB-19) and non-tumor cells (L929). Last, antibacterial activity was assessed through against Staphylococcus epidermidis (25923), Staphylococcus aureus (12228), Escherichia coli (25312) and Pseudomonas aeruginosa (27853). The phytochemical investigation indicated the presence of these metabolite groups: flavonoids, triterpenes, steroids and tannins. The methanolic extracts showed moderate antibacterial activity against S. aureus, S. epidermidis and P. aeruginosa. T. papyrus extracts showed high cytotoxic activity against promyelocytic leukemia cell lines (80.43 to 93.31%). The other lines did not reveal good activity against the extracts tested.
A Bibliometric Analysis of The Impact of COVID-19 on Maritime Logistics and Ports
Authors: Ardıç Saral Gülşah , Sanrı Özlem
Published: September 2022

Starting from the city of Wuhan in China in March 2020, the Covid-19 virus, which spread all over the world in a short time, affected many areas globally. With the declaration of the epidemic worldwide, a red alert was issued in the national and international community. The significant impact of the restrictions applied to slow the spread of the Covid-19 epidemic, as in many other sectors, has also manifested itself in the economy sector. The maritime industry, which constitutes the most important part of international trade, was caught unprepared for this unexpected epidemic. The purpose of this study is to bibliometrically analyze the articles written on the impact of the Covid-19 pandemic on maritime logistics and ports. Web of Science database was used to conduct the study and 29 articles were reached. The articles were examined in detail in terms of number of publications, keyword analysis, author and journal information, and citation analysis. It is aimed that the results of the bibliometric study will guide future studies in this field.
Fiziksel Algının Mekan Değerlendirmesi Üzerindeki Etkisi: Kapalı Kayak Merkezleri ve Türk Milli Takımı Sporcuları
Authors: Demirci Gamze , Arabacıoğlu Burçin Cem
Published: September 2022

Kullanıcılarına iç mekanda kayak yapma fırsatı sunan kapalı kayak merkezleri, ülkemiz için yeni bir kavram olsa da aslında dünya çapında bir süredir adından bahsettirmektedir. Ülkemizdeki gelişim uygulamaları için bu merkezlerin belirli parametrelere göre değerlendirilmesi ve bu değerlendirmelerin sonucunda kullanılabilecek verilere ulaşılması araştırmanın konusunu oluşturmaktadır.
Yılın büyük bir kısmını antrenman için kar üzerinde geçiren, kapalı kayak merkezlerinin aktif kullanıcıları olan sporcuların iklimin, eğimin, ışığın, sıcaklığın, manzaranın, malzemenin ve yönelimin yapay olduğu bu mekanlarda performanslarını ve öne çıkmalarını sağlayan belirleyici noktalarını nasıl etkilediği çalışmaları ise henüz değinilmemiş bir araştırma konusu. Bu bağlamda; bu çalışma, yapay çevre koşullarının profesyonel kullanıcı algısındaki etkin rolünü araştırmayı amaçlamıştır.
Kanunilik İlkesi Kapsamında Ek Mali Yükümlülüklerin Değerlendirilmesi
Authors: Karaş Göksel
Published: September 2022

Vergilerin kanuniliği ilkesi kapsamında vergilendirme yetkisi yasama organına aittir. Vergiler konulurken, değiştirilirken ve kaldırılırken kanuna dayalı olarak yapılması gerekmektedir. Ancak ekonomik ve sosyal bir takım nedenlerden dolayı bazı alanlarda vergilendirme yetkisi yürütme organına devredilebilmektedir. Bu alanlardan birisi dış ticaret alanıdır. Dış ticaretin ülke ekonomisi yararına düzenlenmesi amacıyla vergi ve benzeri mali yükümlülükler dışında ek mali yükümlülük koyma yetkisi Anayasa 167. madde kapsamında yürütme organına devredilmiştir. Ek mali yükümlülüklerin yürütme organı tarafından konulup kaldırılması, vergilemenin kanunilik ilkesine aykırılık oluşturup oluşturmadığı sorusunu akla getirmektedir. Buradan hareketle çalışmanın amacı dış ticaret işlemleri üzerinden alınan ek mali yükümlülüklerin anayasada yer alan kanunilik ilkesi kapsamında değerlendirilmesidir. Bu açıdan bakıldığında gerek Anayasa Mahkemesi kararları gerekse dış ticaretin sahip olduğu nitelikler açısından ek mali yükümlülük koyma yetkisinin yürütme organına devri vergilemenin kanunilik ilkesine aykırılık oluşturmamaktadır.
Leder
Authors: Husted Mia , Borup Jensen Julie , Harju Anne
Published: September 2022

Dette temanummer sætter fokus på forskningens engagement i marginaliserede, udsatte, udgrænsede eller usynlige former for liv og viden og på forskningens bidrag til, at sådanne former for viden og liv kan bidrage til udvikling af egne livsforhold. Artiklerne i dette nummer bibringer viden og metoder til at understøtte marginaliserede former for videns bidrag til forandring og belyser samtidig muligheder, dilemmaer og spændinger i forskningens engagement i social ulighed, sociale reformer og forandring.
Diabetic kidney disease treatment: new perspectives
Authors: Tong Li-Li , Adler Sharon G.
Published: September 2022

Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-stage kidney disease worldwide, as the obesity epidemic and the burden of diabetes continue to rise globally. In general, guideline management of patients with DKD recommends lifestyle modifications, blood pressure and glycemic control, and dyslipidemia treatment along with other cardiovascular disease risk reduction measures. The inhibition of the renin-angiotensin system (RAS) using an angiotensin-converting enzyme inhibitor or an angiotensin II receptor blocker remains the foundational therapy for DKD. In type 2 diabetes (T2D), significant advances in therapeutics, including the sodium-glucose cotransporter-2 inhibitors (SGLT2i), the glucagon-like peptide-1 receptor agonists (GLP-1 RA), and the nonsteroidal mineralocorticoid receptor agonist (MRA) finerenone, have dramatically expanded the armamentarium for treating DKD and its cardiovascular complications. Initiating, optimizing, and sustaining evidence-based pharmacological therapy using a therapeutic combination of RAS inhibitor + SGLT2i/GLP-1 RA + nonsteroidal MRA + statin is likely to significantly improve outcomes for T2D with DKD. Research into potential novel therapeutic targets for DKD remains particularly active and brings much anticipation and optimism to this field.
Novel biomarkers for diabetic kidney disease
Authors: Jung Chan-Young , Yoo Tae-Hyun
Published: September 2022

Although diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in patients with diabetes mellitus; its prevalence has failed to decline over the past 30 years. To identify those at high risk of developing DKD and disease progression at an early stage, extensive research has been ongoing in the search for prognostic and surrogate endpoint biomarkers for DKD. Although biomarkers are not used routinely in clinical practice or prospective clinical trials, many biomarkers have been developed to improve the early identification and prognostication of patients with DKD. Novel biomarkers that capture one specific mechanism of the DKD disease process have been developed, and studies have evaluated the prognostic value of assay-based biomarkers either in small sets or in combinations involving multiple biomarkers. More recently, several studies have assessed the prognostic value of omics- based biomarkers that include proteomics, metabolomics, and transcriptomics. This review will first describe the biomarkers used in current practice and their limitations, and then summarize the current status of novel biomarkers for DKD with respect to assay- based protein biomarkers, proteomics, metabolomics, and transcriptomics.
Pathological validation of the Japanese Renal Pathology Society classification and challenges in predicting renal
prognosis in patients with diabetic nephropathy
Authors: Kim Taeyeong , Kwak Yooujin , Lee Jun Young , Shin Hanwul , Kim Jae Seok , Yang Jae Won , Eom Minseob
Published: September 2022

Background: Diabetic nephropathy (DN) accounts for approximately half of all cases of chronic kidney disease (CKD) and end-stage kidney disease worldwide. The Renal Pathology Society (RPS) classification has been used to predict the renal prognosis in DN. In 2018, the Japanese Renal Pathology Society (JRPS) proposed a comprehensive classification system that included pathological changes in the kidney. The clinical significance of the JRPS classification system was comparatively evaluated in the present study. Methods: A total of 93 cases diagnosed with DN from 2009 to 2019 were enrolled. JRPS scores (J-scores) were calculated by scoring the pathological factors in the JRPS classification system and comparing them with clinical parameters. Results: Most pathological factors constituting the J-score were significantly correlated with clinical factors. Laminated nodules were inversely correlated with estimated glomerular filtration rate. After adjusting for age, sex, body mass index, hemoglobin A1c, diabetes duration, and hypertension, CKD stage was significantly correlated with JRPS grade, nodular lesions, and exudative lesions in the multivariate logistic regression analysis. However, receiver operating characteristic curve analysis revealed that the J-score (area under the curve [AUC] = 0.639) had lower clinical significance than the traditional RPS classification system (AUC = 0.675). Conclusion: The JRPS classification can more comprehensively reflect renal changes than the RPS classification and is correlated with renal survival. When creating a new pathological classification, arteriolar hyalinosis should not be included, whereas laminated nodules should be included.
Replacing Methotrexate with Letrozole in Cases of Early Ectopic Pregnancy as an Innovative Therapy - A Short Communication
Authors: Kulvinder Kochar Kaur
Published: September 2022

In cases of early ectopic pregnancy the only medical therapy advocated till now has been single or multiple dose methotrexates with some preconditions. Here the role of an aromatase inhibitor, letrozole is discussed as a novel drug that possibly can be considered for replacement of methotrexate in view of its simplicity of use, cheap, relatively free of side effects associated with methotrexate, not having many contraindications other than the haemodynamic stability, size of mass, ruptured ectopic pregnancy. Currently letrozole is being utilized commonly for the treatment of hormone sensitive breast cancer, besides as a drug for ovulation induction in cases of poly cystic ovarian syndrome (PCOS). Only more randomized controlled trials (RCTs) are needed before one can safely utilize it in routine clinical practice without fear of any haematological side effects of methotrexate.
Penerapan Model Pembelajaran Kooperatif Tipe TGT (Teams Games Tournament) untuk Meningkatkan Motivasi Belajar Siswa pada Pembelajaran Sosiologi Kelas Xl IPS 1 SMAN 1 Lubuk Basung
Authors: Handayani Lidiya Putri , Nurlizawati Nurlizawati
Published: September 2022

This study aims to analyze the increase in learning motivation of students class XI IPS 1 SMAN 1 Lubuk Basung in sociology learning, by applying the Team Games Tournament (TGT) type cooperative model for the 2021/2022 academic year. To analyze the problems in this study, the researcher uses the learning theory by Thorndike which says that a response or learning process followed by pleasant conditions by giving gifts or praise will strengthen the learning process. This type of research is Classroom Action Research (CAR) with 26 research subjects in class XI IPS 1. The approach model used by Kemmis and Mc. Taggart which consists of four components: planning (planning), action (acting), observation (observation), reflection (reflecting). The data collection technique used is observation and interviews. The research instrument used in this research is an observation sheet. Analysis Techniques Observational data used quantitative descriptive data analysis techniques.The results showed that from the analysis of observational data in the study of increasing learning motivation with the application of the Team Games Tournament learning model, the students of class XI IPS 1 SMAN 1 Lubuk Basung experienced an increase. The highest increase is that it is not easy to let go of things that are believed from 50% in the first cycle to 90.38% in the second cycle, this is because. Can maintain the opinion of 55.76% to 88.45% in the second cycle. This can be seen from the activeness of students in expressing opinions in class or students who ask and provide questions about the material being studied, these active students are also influenced by the additional value given by the teacher if they are active in the learning process. The difference in the average increase from the first cycle to the second cycle is 26.51%. The average in the first cycle from 58.40% to 73.89% in the second cycle. The conclusion that can be drawn from this discussion is that by applying the Team Games Tournament (TGT) type of cooperative learning model, it can increase students' motivation to learn sociology in class XI IPS 1 SMAN 1 Lubuk Basung.
ANALISIS PERENCANAAN DAN PENGANGGARAN PENDIDIKAN DI KABUPATEN SOLOK SELATAN
Authors: Sugiarto Toto
Published: September 2022

This research is aim to identify and also evaluate document about planning and budgeting of educational in regancy South of Solok and also formulate policy, program, activity of relevant educational so that can finish problems of education in regancy South of Solok. Data is used in this research is primary data and data of sekunder. Method analysis that is: method analyze classification of problem of educational, Analyze SWOT, and Analysis Planning and Budgeting of Education in the regancy South of Solok. Result of planning document analysis (educational RPJPD, education RPJMD, RKPD, Renstra and  Renja of duty Education) and analysis budgeting document (KUA and APBD) in middle and elementary educational in regancy South of Solok, not yet followed compilation order pursuant with Law number 25/ 2004, about Systems Planning of National Development.
MERANCANG PROSES PEMBELAJARAN PKN YANG MENYENANGKAN DI SMP N 4 PELEPAT ILIR
Authors: Sukarno Sukarno
Published: September 2022

PKn  Subject  is  the  cultivication concept  subject  of  national  awareness, Pancasila, hard working attitude and responsiblity. Most of its material are concept. For giving the materials of learning, teacher have to have their own trick, so that the materials can be planned in easy by  student. This research design study process which is  fun  for student at  PKn  subject. Interlude technique at learning is designed in order to support learning in the class. As a result, this research can increase the student study report.
PENERAPAN PEMBELAJARAN MATEMATIKA DENGAN PENDEKATAN KONTEKSTUAL DI KELAS X.B SMA NEGERI 1 INDRALAYA SELATAN
Authors: Wibowo Wahyu , Hartono Yusuf , Saleh Trimurti
Published: September 2022

This research is a descriptive research that have a purpose to know description of learning math application by contextual learning approachment which is evaluated from student activity and the student study result after following math learning with contextual approachment in the X.B SMA Negeri 1 Inderalaya Selatan class. These research subjects number 25 student of X.B SMA Negeri 1 Indralaya Selatan school year 2013/2014 class. Technique of data accumulation that was done are by observation and test. The carried out data of student learning activity is collected with observation. While the test is used for knowing the student learning result after studying math by contextual approachment. As for carried out percentages of student learning activity at learning application by contextual approachment is equal to 72% that include in good category. While the percentages of efficacy student studying result mean equal to 75,48 that are categorized as a good one. So that from that assessment can be concluded that learning math application by  contextual learning approachment which is  evaluated from student activity and the student study result can be categorised as a good one.
TOMPEL (TONG SAMPAH PENGHASIL ENERGI LISTRIK)
Authors: Mayolan Bingesti Vegi , Chandra Ade , Azhar Willy , Rahmatesa Fitri , Handessa Vebby Ola , Hamid Muhammad Imran
Published: September 2022

Plastic waste is the main problem that we face in Indonesia and still there is no appropriate way to solve it. Indonesia is ranked in number two as the country that throwing plastic waste to the sea. The common solution that mostly developed is by using recovery method, which is recycling the materials or compounds that exist in trash even it is physically, chemically, biologically or thermally. In this case it is needed a prototype for recovery system in changing trash into electrical energy. A prototype named TOMPEL (basket case generating electrical energy) has its function besides the place to put trashes but also has its function as converting tools to convert energy from plastic combustion into electrical energy with thermoelectricity system. The output is DC electricity that converts into AC electricity so it can be used after that. Based on experiment that has been done, the conclusion is effective plastic mass is 200 gram with outer voltage 10 volt by using glass wool as isolator. The voltage can recharge power in mobile phone. Moreover, solid waste is transformed into bricket.
PENTINGKAH ADVERSITY QUETIENT DALAM PENCAPAIAN PRESTASI AKADEMIK DI PERGURUAN TINGGI?
Authors: Cerya Efni
Published: September 2022

The quality of education remains a central issue amidst the polemic of the education system in Indonesia. Educational goals that initially emphasize changes in behavior and mindset shift to value-oriented, graduation and even prestige. This has implications for graduates who are weak in self character, not ready to plunge into society and easily fragile to accept failure. Many individuals have high intelligence, but low in emotional and adversity quotient. For that, it is very important for students in improving and managing adversity quotient so that students will be more resilient in facing the problem and academic achievement.
Pelaksanaan Olahraga Bulu Tangkis Siswa Tunagrahita
Authors: Fahmi Nur , Efendi Jon
Published: September 2022

This study aims to describe the implementation of badminton for intelectuall disability students in SLBN 1 Bukittinggi which includes implementation, obstacles, and solutions. The subjects in this study were sports counseling teachers. Supporting information was obtained from school principals, student representatives, and students participating in badminton sports activities. Data collection techniques used are observation, interviews, and documentation. The results showed that the implementation of tagging feathers was carried out with warm-up preparation before the exercise in the form of running around the field, training activities carried out three times a week, namely on Monday, Wednesday, and Friday starting from 13.00 - 16.00. The exercise is carried out using demonstration methods and training methods. Obstacles encountered in the implementation of badminton sport are students more often following moods, lack of motivation, for the beginner giving material requires considerable time and the solutions taken are giving direction and support to students and fostering students since elementary school as the next generation.
Pendidikan Karakter Melalui Islamic Boarding School di SMP Plus Ar-Rahmat Bojonegoro
Authors: Ihsani A. Fikri Amiruddin , Febriyanti Novi
Published: September 2022

This research discusses character education in the Middle School Plus Ar-Rahmat Bojonegoro. There are two issues to be discussed, how the character education process through Islamic Boarding School and how the role of each school member in character education through Islamic Boarding School. This research uses qualitative methods with descriptive analysis through observation, interview and documentation. The research showed; (1) the process of character education from within the classroom adopts the values of character education from the Ministry of Education and Culture. From outside the classroom, students are provided with religious values, good social environment, instilling disciplined and independent values, maximizing communication among students, caring for friday activities, helping fellow students, and establishing friendships. (2) the role of each school member in character education consists of; the principal acts as a role model, social control, and mobilizer. The curriculum has the role of integrating religious science and general science. The chaplain/teacher acts as a companion and an example. And students play a role in the success of character education by actively participating and raising awareness. Islamic Boarding School is present as a solution to the many new cultures that enter the era of digitalization.
PEER AND AUTOMATED WRITING EVALUATION (AWE): INDONESIAN EFL COLLEGE STUDENTS’ PREFERENCE FOR ESSAY EVALUATION
Authors: Ginting Rita Seroja , Fithriani Rahmah
Published: September 2022

A plethora of studies have investigated the effects of peer evaluation (PE) and automated writing evaluation (AWE) on the writing products and perspectives of English as a foreign language (EFL) students. However, few studies compare students' preferences regarding its utilization to evaluate their essays. This study aimed to determine which method EFL college students prefer for evaluating the quality of their English academic writing. For data collection, a questionnaire was distributed to determine the frequency with which students utilize feedback. Twenty students enrolled in English Education completed the questionnaire. The open-ended interview was then administered to three students in order to gain a deeper understanding of their perspectives on these two modes of evaluation. Frequency count and thematic analysis were utilized to analyze the data. The results indicate that students favor using peer feedback over Grammarly, the AWE software used in this study, for two reasons. First, they view their peers as their real audience, and second, they value their peers' comments more than Grammarly's. However, Grammarly also received positive point as the students enjoys writing with this tool. Therefore, it is believed that the combination of these two s will result in the most essay writing progress.
Risâle-i Merâsim-i Bektaşi Adlı Esere Göre Bektaşi Nasıl İkrar Verir?
Authors: ÖĞE Mustafa
Published: September 2022

Bektaşiliğin Babagân kolundaki en önemli törenlerden biri, kişinin miracı olarak kabul edilen ikrar erkânıdır. Bektaşi inancına göre ikrar veren nasip alır. Yani manevi sırlara vakıf olmaya başlar ve kişisel olarak olgunluğa erişinceye kadar bu içsel yolculuk devam eder.

Babagân Bektaşiliğine ait ikrar erkânlarını anlatan eserler vardır ve bunlara çatı bir isim olarak erkânnâme denir. Bu eserlerin büyük kısmı, Osmanlı döneminde Arap harfleriyle ve Türkçe kaleme alınmıştır. Çalışmanın konusu da Milli Kütüphane Yazmalar Koleksiyonunda 06 Mil Yz A 2714 yer numarasıyla kaydedilen ve ikrar erkânını anlatan Risâle-i Merâsim-i Bektâşi adlı erkânnâmedir. Tamamen İslami referanslarla kaleme alınan Risâle’-i Merâsim-i Bektâşi, mensur ağırlıklı olmak üzere mensur-manzum karışık bir eserdir.

Bu çalışmada öncelikle erkân ve erkânnâmeler hakkında kısa bilgi verilmiş ve Risâle-i Merâsim-i Bektâşi adlı eserin tanıtımı yapılmıştır. Bundan sonra Risâle-i Merâsim-i Bektâşi adlı eserin içerik analizi yapılmış ve özellikle Bektaşilik inançları açısından metin değerlendirilmiştir. Daha sonra eserin çeviri yazısı yapılmış ve en sonda da eserin orijinal metnine yer verilmiştir.
The quality of television news in Indonesia
Authors: Putri Vinanda Cinta Cendekia , Sonni Alem Febri
Published: September 2022

This research aims to explore the watching patterns of the people of Indonesia with a specific focus on how they consume news programs on television. Indonesian democracy condition is draining much information energy every year. The war for information among broadcasting institutions has stirred worry among the general public regarding the quality of the content broadcast by national television stations. Virtually no medium is safe from the touch of politics, and news programs, in particular, are often highly political. Due to the urgency of this research to measure the quality of programs, not the number of viewers, the informants of this study are industry experts and academics. Their knowledge, experience, and insight into the television industry make them exceptionally qualified to assess television programs' quality critically. The results of the evaluation and deepening of the experts can be concluded by several aspects of the quality of news programs: The intervention of media owners is still evident and even conspicuous in the balance of news in an industry where broadcasting institutions are explicitly manipulating news content, especially when it concerns political issues. Concerning critical power, several news programs fail to arouse a critical rationale. News is delivered from one perspective only. The supervision aspect is still deficient because the shocking and horrible are intrinsically appealing. Subjectiveness in the news is widespread, especially in the selection of titles and narratives that simply justify the reporters' words.
Clave para la identificación de Chironomidae (Diptera) de la ecorregión Tributarios del río Paraná y Río de la Plata mediante la utilización de exuvias pupales
Authors: Zanotto Arpellino Juan Pablo , Montalto Luciana , Donato Mariano
Published: September 2022

Chironomidae es uno de los taxones más importantes de los ecosistemas de agua dulce. Las exuvias pupales se utilizan como una forma simple y rápida de obtener información ecológica sobre hábitats acuáticos y autoecología y distribución geográfica de las especies. El objetivo de este estudio fue elaborar una clave de identificación de pupas de Chironomidae presentes en los arroyos de la ecorregión Tributarios del río Paraná y Río de la Plata, integrando información relevada en estudios recientes, con el conocimiento disponible en publicaciones previas. El estudio de las exuvias pupales permitió ampliar el conocimiento de la riqueza taxonómica y la distribución de géneros y especies previamente registrados para la región. Por otro lado, la aplicación de la Técnica de Exuvias Pupales de Chironomidae posibilita identificaciones precisas a nivel de especie/morfoespecie y una reducción del tiempo de muestreo y procesamiento de las muestras resultando eficiente y menos costosa. Esta clave es el resultado del conocimiento de la familia en la ecoregión desde hace varias décadas y constituye un primer aporte al conocimiento taxonómico de Chironomidae a nivel de especie.
Utilization of Unconventional Water Resources (UWRs) for Aquaculture Development in Arid and Semi-Arid Regions – A Review
Authors: Soleimani-Sardo Mojtaba , Khanjani Mohammad Hossein
Published: September 2022

Today, the increase of the world’s population and climate change has resulted in the reduction of fresh water resources and the increase of arid and semi-arid areas, and thus, it is necessary to find a new solution to increase the production of food resources. Aquaculture is one of the sources of food production, which can play a key role in fighting poverty and hunger. Sustainable aquaculture is strongly dependent on water quantity and quality, and also, optimal fish production can be determined by the physical, chemical and biological quality of water. Due to the current restrictions and the global increase in demand for aquatic products, unconventional waters (UWs) have been used in aquaculture. UWs include: recycled water, sewage, saline water, agricultural drains and water resulting from the process of sweetening and desalination of salty water. Today, these water resources have been used to grow all kinds of aquatic animals to provide food and protein. Considering the limited water resources in the world, the use of UWs is very effective and efficient in managing drought, and is considered as one of the ways to develop food production for humans. Due to its importance in areas facing water scarcity, the use of unconventional water resources (UWRs) to supplement or replace the use of conventional fresh water sources has been considered. In this review study, the importance of UWs and their sources, aquaculture products and aquatics that can be cultivated with the help of UWs are discussed.