bluuebunny/crossref_metadata_2025 huggingface dataset:
Responses of avocado (Persea americana) to various doses of compost fertilizer and watering interval
Authors: Kansih Sri Hartini  , Afifuddin Dalimunthe  , Vinny Alvionita Br Tarigan  , Aqilah Insani
Published: January 2024

Avocado is a multifunctional plant that can be utilized in all parts. The growth of avocado and its yield can be achieved by fulfilling requirements for the growth and maintenance of the plant well. Planting on dry land requires the addition of organic fertilizer and optimal water requirements to increase organic matter content and plant fertility. This research aims to obtain the optimal dosage of compost and watering intervals for the growth of avocado (Persea americana). The research was carried out in the Greenhouse Faculty of Agriculture, Universitas Sumatera Utara. This research used a factorial completely randomized design (F-CRD) with the addition of compost fertilizer doses (K0:0 kg, K1:0.5kg. K2: 1 kg. K3: 1.5 kg and K4: 2 kg) and watering intervals (A1: once a day. A2: once every three days. A3: once every five days and A4: once every seven days) with parameters of observation of height, diameter, top fresh weight, root fresh weight, top dry weight and root dry weight. The results showed that the interaction of compost and watering intervals significantly affected the height and diameter increase, root fresh weight, and root dry weight of avocado plants. The interaction of giving 1.5 kg of compost and watering intervals every day had the best effect on the growth and quality of avocado seedlings
METHODICAL APPROACH TO THE COMPLEX ASSESSMENT OF THE DEVELOPMENT OF THE INVESTMENT POTENTIAL OF THE TOURISM INDUSTRY
Authors:   National University ", Tsviliy Sergiy ,   Zaporizhzhia Polytechnic"
Published: January 2024

The relevance of the topic lies in the existence of an urgent need for scientific improvements and taking into account the conditions of conflict and post-conflict recovery of the tourism economy based on the analysis of investment potential. The purpose of the study is to substantiate the introduction of a methodical approach to the comprehensive assessment of the development of the investment potential of the tourism industry on the basis of the sustainable and purposeful application of budget stimulation tools. Research methods: descriptive, analytical, weighted assessments, rating ranking, forecasting, integral indices, scenarios, generalization. The functional structure of the tourism industry is presented. The system of synthetic indicators of the development of the investment potential of the tourism industry by the level of targeted use of budgetary stimulation tools is summarized. It is proposed to carry out an assessment of the development of the investment potential of the tourism industry by stages, taking into account the peculiarities of business in the regions of the country. A methodical approach to the assessment of the development of the investment potential of the country's tourism industry based on the level of targeted use of budget incentives has been developed, which is based on basic methodological principles that are extended from the approach of individual assessment of synthetic indicators and have a significant impact on the level of development of the investment potential of the tourism industry in the regions of the country. The calculation apparatus for the application of the methodical approach is grouped. The distribution of tourist sub-complexes in the regions of Ukraine in different geographically located territories according to the quantitative value of budgetary stimulation of investments in the material and technical support of the subjects of the tourism industry is presented. Hierarchical clustering of tourism sub-complexes of Ukraine was visualized and the ranking of the parameters of development of the investment potential of the tourism industry of Ukraine according to the quantitative criteria of budgetary stimulation of investments in the material and technical support of tourist sub-complexes in different territories of their geographical location was carried out.
COMMON AGRICULTURAL POLICY OF THE EUROPEAN UNION: EXPERIENCE AND PROSPECTS FOR UKRAINE
Authors:   The National Academy of Agrarian Sciences of Ukraine, Kvasha Serhii ,   National University of Life and Environmental Sciences of Ukraine, Vakulenko Vitalii ,   National University of Life and Environmental Sciences of Ukraine
Published: January 2024

The article is devoted to defining the features of the Common Agricultural Policy of the European Union as an important direction of the EU policy at the present stage. The purpose of this article is to identify the main features of the Common Agricultural Policy of the European Union and the possibilities of their application in Ukraine at the present stage. The agrarian sector is the main sector of Ukraine's economy, which is currently in a negative state in the context of war, which necessitates its improvement. Among the possible steps is the introduction of the EU Common Agricultural Policy experience. Thus, the article analyses the features of the EU's Common Agricultural Policy and identifies the possibilities of its application in Ukraine. The main features of the EU's Common Agricultural Policy are investigated, and the basic definitions of this concept are provided. The peculiarities of historical development are clarified and the main stages of evolution of the Common Agricultural Policy are defined. The structure of the Common Agricultural Policy of the European Union is defined. The main directions of the EU's Common Agricultural Policy are analysed and the general features of the current "pillars" of the Common Agricultural Policy are identified. of the Common Agricultural Policy. The basic principles of implementation of the Common Agricultural Policy at the present stage and the measures envisaged by it are determined. Particular attention is paid to the issue of cooperation between Ukraine and the EU in agriculture. The main features of Ukraine's agrarian policy are investigated, and existing shortcomings are identified. On this basis, the author outlines the possibilities of implementing the Common Agricultural Policy in Ukraine. The results of the study emphasise the possibility of introducing the EU experience in agricultural policy and the strategic importance of introducing this experience for the Ukrainian economy in the post-war period. The findings have possible scientific implications and confirm the need to use EU experience for the development of the Ukrainian agricultural sector after the war.
FISCAL SUSTAINABILITY AS AN ELEMENT OF NATIONAL ECONOMIC SECURITY IN THE CONTEXT OF GEOPOLITICAL RISKS
Authors:   SHEI ", Tymoshenko Maryna ,   Pryazovskyi State Technical University"
Published: January 2024

Fiscal sustainability is crucial for the overall economic security of a country. It means the ability of the government to meet its financial obligations in the long run without relying on excessive borrowing and without resorting to inflationary policies. The purpose is to explore the key challenges to strengthening fiscal sustainability as an element of national economic security in the face of new geopolitical risks. Global economic crises, such as the 2008 financial crisis, the coronavirus pandemic, the war in Ukraine, crisis events in the banking sector in March 2023 can also affect fiscal sustainability. Economic crises can lead to a decline in demand for goods and services, lower tax revenues, and increased government spending on social programs such as unemployment benefits. This can lead to an increase in public debt and budget deficits. High levels of public debt also increase the risk that the government will default on its obligations, which could undermine investor confidence and increase borrowing costs. This can further exacerbate the problem of high public debt, as the government may have to devote even more resources to servicing this debt. According to the concept of "debt rejection" for developing countries, as a rule, there is a "lack of freedom" regarding the regulation of the debt level, although it is managed using the most modern methods. Identifying the determining factors for a specific country, highlighting the threshold of "rejection" of debt is a basic approach to debt management, in particular, its restructuring, determining an acceptable level of debt, using international lending to mitigate fiscal shocks and accelerate growth. To address the problem of high public debt, governments can implement measures such as spending cuts, raising revenues through taxation, or implementing structural reforms to improve economic growth. However, these measures can be difficult to implement as they may require difficult choices and sacrifices. Nevertheless, addressing high public debt is important for achieving fiscal sustainability and promoting national economic security.
МЕДИЧНИЙ СПА- ТА САНАТОРНО-КУРОРТНИЙ ТУРИЗМ: ВІДМІННІСТЬ КОНЦЕПЦІЙ
Authors: Щука Галина Петрівна , Лемко Іван Степанович , Шейко Віталій Ілліч
Published: January 2024

Санаторно-курортний туризм переживає кризу, яку намагається подолати шляхом диверсифікації та комерціалізації послуг, що поступово перетворює його у медичний спа-туризм. Мета дослідження – визначити наслідки цього процесу, встановивши спільне та відмінне у концепціях санаторно-курортного та медичного спа-туризму. Методологія дослідження: системно-структурний підхід, методи аналізу та синтезу, індукції та дедукції, прогнозування, аналогії, наукового узагальнення, співставлення та порівняння. Результати дослідження: визначено спільне, відмінне та індивідуальне у концепціях цих видів туризму. Практичне значення: виокремлено характерні риси, які відрізняють санаторно-курортний туризм від медичного спа-туризму, і можуть бути втрачені внаслідок злиття цих сегментів.
Multi-Class Multi-Level Classification of Mental Health Disorders Based on Textual Data from Social Media
Authors: Sutranggono Abi Nizar , Riyanarto Sarno  , Imam Ghozali
Published: January 2024

Mental health disorders pose a significant global public health challenge. Social media data provides insights into these conditions.Analysing text can help identify indications of mental health disorders through text-based analysis. However, despite the largenumber of studies on the analysis of mental health disorders, the predominant algorithm in the existing literature is the Multi-ClassSingle-Level (MCSL) classification algorithm, which is often used for simple classification tasks involving a limited number of classes.Typically, these classes are binary, representing either an unhealthy or a healthy mental state. This paper uses English text data from Reddit to classify mental health disorders. The Multi-Class Multi-Level (MCML) classification algorithm was applied to perform detailedclassification and address the limitations of the research scope using several approaches, including machine learning, deep learning, and transfer learning approaches. Two different pre-processing scenarios were proposed to handle unstructured text data, one of the most challenging aspects of classifying text from social media. The results of the experiments show that the MCML classification algorithm successfully performs detailed classification and produces promising results for each classification level. The proposed pre-processing scenario influences the performance of each classifier and improves classification accuracy. The best accuracy results were obtained for the Robustly Optimised BERT Pre-training Approach (RoBERTa) classifier at level 1 and level 2 classifications, namely 0.98 and 0.85, respectively. Overall, the MCML classification algorithm is proven to be used as a benchmark for early detection of text-based mental health disorders.
A non-invasive approach to measuring body dimensions of wildlife with camera-traps: a felid field trial
Authors: Paton Alexandra , Brook Barry , Buettel Jessie
Published: January 2024

Dimensions of body size are an important measurement in animal ecology that can provide information on species, sex, diet, and body condition. However, these measurements are difficult to obtain as most methodologies require the capturing and handling live animals. These invasive approaches result in logistical challenges, particularly when studying dangerous or difficult to trap species. We present a novel approach to measuring body dimesons utilising camera-trap images. Unlike prior methodologies, our technique allows for retrospective analysis with existing datasets and eliminates the need for permanent distance markers. We apply our method utilizing feral cats as our study species. The precision of our methodology was evaluated by comparing size estimates across individual cats. Average cat height was 27.4 cm (SE = 0.002 cm) and average length was 52.6 cm (SE = 0.003), with individuals showing consistent measurements across images (average standard error of 0.95 cm for height and 1.9 cm for length). Our method provided precise estimates of body size, highlighting the potential for camera-traps to supplement morphological information in trap-shy populations. We call for further trials of this method, preferably with individuals of known size, to better assess its accuracy.
Positive Psychology in International Student Development: What Makes Chinese Students Successful?
Authors: Liu Wei , Yu Cheryl , McClean Heather
Published: January 2024

Most of the current literature on the experiences of Chinese international students tends to adopt a deficit-based approach, focusing on the weaknesses, problems, and challenges Chinese students face while studying overseas. In other words, they tend to focus on struggling Chinese students, “problem” Chinese students, and Chinese students who are failing their overseas studies. Though the intention may be good, these studies may strengthen a negative stereotypical image of Chinese international students that is problem ridden. This study aims to introduce some positive psychology in international student development by focusing on successful Chinese students, their success stories, and what success secrets they can share with future Chinese students studying abroad. With the completion of an undergraduate program adopted as a minimum threshold of student success, this study aims to glean the experiences of successful Chinese students in the United Kingdom and disseminate them as lessons for future students. The study finds that proactiveness in networking and seeking support, open and adaptive attitude toward learning and life, and metacognitive skills in self-management are the most important factors contributing to Chinese students’ success in overseas studies.
VIRTUAL OUTCROP MODELS OF GEOLOGICAL STRUCTURES
Authors: Tavani Stefano , Corradetti Amerigo , Mercuri Marco , Seers Thomas
Published: January 2024

This textbook aims to introduce the reader to the basic principles and methods of virtual outcrop models and their applications within structural geology. We first provide the reader with the basic concepts of virtual outcrop models and an overview of methods commonly employed for digitally scanning outcrop surfaces: lidar and Structure from Motion - Multi-VIew Stereo (SfM-MVS) photogrammetry. We then focus upon SfM-MVS photogrammetry, illustrating its fundamental concepts. Finally, we illustrate key applications of virtual outcrop models in the field of structural geology. In addition, the book features six training exercises that serve to illustrate the fundamental steps and issues related to the creation and interpretation of models.
Analysis of Improving Business Performance in the Creative Industry Through Management of Human Capital, Social Capital, and Innovation Capability in the Era of Society 5.0
Authors: Halim Fitria , Kusuma Rr. Chusnu Syarifa Diah , Sherly Sherly , Panggabean Esther Praja Anggriany , Sudirman Acai
Published: January 2024

In the era of Society 5.0, creative industry businesses must be able to optimize human capital, social capital, and innovation capability to improve business performance so that it is more optimal. This study aims to analyze the increase in creative industry business performance through managing human capital, social capital, and innovation capability in society 5.0. This study used a library and field research design with a causal associative approach. This study used a total sample of 150 samples. Data analysis confirms that human capital, social capital, and innovation capability significantly affect business performance. The implications of this research highlight the importance of organizations in the creative industries having to invest more in developing their human resources. This can be done through appropriate training, further education, skills development, and hiring. Focus on developing human resources will help improve the quality of the workforce and produce better innovation. Organizations must build and strengthen social relationships with business partners, customers, educational institutions, and related communities. Collaboration and knowledge exchange with relevant parties can help improve access to resources, market opportunities, and new ideas. Further, organizations must prioritize innovation efforts and create an environment encouraging creativity and experimentation. It is essential to develop a culture of innovation throughout the organization, encourage employees to share ideas, provide adequate support and resources, and adopt a flexible and adaptive management approach.
BUSINESS FEASIBILITY ANALYSIS OF D’SWEETY LAYERS DESSERT CAKE
Authors: Putri Berliana , Sonny Sonny
Published: January 2024

Dessert is a food served as a cover after the main food that is often found in various countries, including Indonesia. In Indonesia, dessert is usually called "makanan pencuci mulut". Dessert is identical with a sweet taste that is able to arouse the appetite of those who see it because of its attractive appearance. Therefore, an analysis will be carried out regarding the feasibility of the business in the dessert industry to be able to determine the sustainability of the business. In this business plan, a name will be given according to the dessert product that will be launched later, namely D'Sweety Layers which can describe a layered dessert cake with a sweet taste, which is called layers crepes cake. The target audience segmentation is the millennial generation and Z generation, who have so far been accustomed to following trends. Then expand the range not only offline stores but can be ordered online through the food delivery platform.
Policy Discourse on Restructuring Work Entry and Return Hours Based on Indicative Inquiry of the Jakarta Transportation Council
Authors: Hanafiah Hally , Hadiansah Ihsan , Yulian Karina
Published: January 2024

Recent data, observations and research show that the level of congestion at peak hours in Jakarta from mid-2022 to throughout 2023 has matched or even exceeded the level of congestion in 2019, or the time before the COVID-19 pandemic. One discourse to reduce the high level of congestion in DKI is the implementation of a policy to rearrange office hours in DKI and between May 22, 2023 and June 2, 2023 DTKJ conducted an indicative online questionnaire entitled "Survey on Rearrangement of Working Hours in DKI Jakarta" which covered 881 respondents. Based on the results of the indicative questionnaire, DTKJ recommended improvements to the public transport sector to be made by the DKI Jakarta Provincial Government, primarily by (i) increasing the public transport fleet, especially to operate during peak hours to reduce waiting time for users at public transport stops, terminals and stations, (ii) increasing the level of safety and comfort in the use of public transport, (iii) expanding service coverage areas to increasingly reach residential areas and suburban areas of DKI Jakarta, and (iv) increasing public transport service routes. The questionnaire results show that the majority, or more than 80 percent, of Jakarta transportation users approve of the implementation of rearranging work entry and return hours as a policy to reduce congestion levels, especially at peak hours. However, based on the results of the same online survey, DTJK concluded that the policy of rearranging work hours is not the main or only policy that can be carried out by the DKI Jakarta Provincial Government because improvements to the public transportation sector are the main steps that must be taken. In addition, the Jakarta Provincial Government is expected to ensure that the various policies that have been implemented can be enforced in the field and even expanded by continuing to review various policies that have the potential to reduce travel demand.
Ocalić od zapomnienia. Z dziejów Towarzystwa Wydawniczego „Ignis” (1920–1925)
Authors: Bańkowska Małgorzata
Published: January 2024

The article presents the results of historical and bibliological research, which objective is to reconstruct the history of the Ignis publishing society established by the Polish Socialist Party (PPS). The first part of the study presents the history of the publishing house reconstructed on the basis of scientific studies, memoirs, and archival materials, as well as the compactness of the bookselling and socio-cultural press in the interwar period. The second part contains the results of quantitative and qualitative (structural) analysis of the publishing repertoire. This study is the first in a series devoted to the activities of the PPS publishing house.
Steam Boilers in Ready-Made Garments Industry in Bangladesh: Existing Scenario and Scope for Development
Authors: Siraj Md Tanvir , Hasan Md Mehedi , Ahmed A N Faisal , Faruk Faisal Bin , Ahmed Md Foysal , Chowdhury Md Kamrul Hasan , Ahmed S M Faysal , Islam Md Sohidul , Sefat E Nur Kazi , Saeed Syed Salman
Published: January 2024

Bangladesh's Ready-Made Garments (RMG) industry, historically prone to hazards including boiler explosions with numerous fatalities, has prompted the RMG Sustainability Council (RSC) to initiate boiler safety inspections. This study addresses the lack of empirical data on boiler operations in RMG factories, focusing on operational scenarios, risk factors, and remediation strategies. Conducted from March 2021 to March 2023, structured visual inspections across 1386 RMG factories assessed 2204 boilers. Key findings reveal that 34.99% of factories predominantly use a single boiler, 91.24% of boilers are government-registered, and the majority are imported (63.29%) with a steam generation capacity below 1,000 kg/hr (59.75%). Additionally, 63.11% were manufactured between 2010 and 2019, 79.63% burn fossil fuels, 54.60% are vertically oriented, and 82% use softened feedwater. The study also identifies 32 external risk factors across 11 categories, providing insights for decision-makers to enhance boiler operation safety and sustainability. By leveraging this inspection data, the research aims to bridge the empirical gap and offer a comprehensive understanding of the existing challenges in RMG boiler operations.
Journal of Engineering Science 14(2), 2023, 89-105
Pendampingan Masyarakat Nelayan Marunda Pasca Pandemi Covid-19
Authors: Herindrasti V.L. Sinta , Oktavian Riskey
Published: January 2024

Sektor kelautan dan perikanan merupakan sektor yang tidak lepas dalam membantu meningkatnya perekonomian Negara. Sektor ini pula menjadi salah satu sektor yang terkena dampak saat pandemi Covid-19. Salah satu daerah yang masih terkena dampak pasca pandemi Covid-19 adalah masyarakat nelayan Marunda sebagai salah satu daerah pesisir laut di Kecamatan Cilincing, Jakarta Utara. Munculnya beberapa kendala di sektor ini memunculkan upaya pendampingan dari Tim Abdimas Task Force 13 Revengers untuk mengatasi kendala-kendala tersebut, melalui observasi berkala, pendekatan berlanjut dengan masyarakat setempat hingga interview untuk menganalisa situasi dan mengidentifikasi masalah yang muncul mengawali pendampingan yang dilakukan mulai dari pembuatan alat tangkap ikan sederhana berupa jaring gillnet, pemasaran dan penjualan hingga pengelolaan ikan mulai dari pembukaan tempat pelelangan ikan yang dapat dihadiri oleh seluruh nelayan hingga pengelolaan ikan asap dengan harga jual yang lebih tinggi, peningkatan potensi wisata pemancingan Marunda dengan cara promotion mix baik secara online maupun offline, serta mengoptimalkan koperasi nelayan melalui sosialisasi kepada para nelayan dan mencanangkan beberapa kegiatan di bawah naungan koperasi nelayan untuk masyarakat di dalam maupun di luar wilayah Marunda dengan harapan dapat meningkatkan potensi nelayan di sektor perikanan pasca pandemi dan seterusnya.
Milli Takım Düzeyindeki Bedensel Engelli Para-Karate Sporcularının Spora Katılım Motivasyonları ile Yaşam Kalite ve Yaşam Doyum Düzeyleri Arasındaki İlişkinin İncelenmesi
Authors: Boz Emre , Kul Murat , Çetintaş Yasin
Published: January 2024

Para-Karate sporcularının spora katılım motivasyonları ile yaşam kaliteleri ve yaşam doyumları arasındaki ilişkinin incelenmesi bu araştırmanın temel amacıdır. Bu amaç doğrultusunda milli takım seçmelerine katılan 24 para-karate sporcusu (n=11kadın-13erkek) çalışmaya dâhil edilmiştir. İlişkisel tarama modelinde gerçekleştirilen bu araştırmada verilerin toplanması adına 4 ayrı form kullanılmıştır. Bunlar; “Kişisel Bilgi Formu”, “Engelli Bireylerde Spora Katılım Motivasyonu Ölçeği”, “Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği” ve “Yaşam Doyum Ölçeği”. Dijital ortamda toplanan bu verilerin analiz sürecinde ise SPSS (26. Versiyon) paket programının tanımlayıcı analizlerinin yanı sıra Spearman Korelasyon Katsayısı testi ve regresyon analizi kullanılmıştır. Veri analizinin neticesinde para-karate sporcularının spora katılım motivasyonları ile yaşam kalite ve yaşam doyum düzeyleri arasında ilişki olduğu tespit edilmiştir. Aynı zamanda içsel motivasyon ve dışsal motivasyon alt boyutlarının hem yaşam doyumunun hem de yaşam kalitesinin yordayıcısı olduğu sonucuna ulaşılmıştır.
4-12 YAŞ ARASI ÇOCUKLARIN PANORAMİK RADYOGRAFİLERİNDE GÖRÜLEN DENTAL ANOMALİLER VE PATOLOJİK LEZYONLAR: BİR RETROSPEKTİF ÇALIŞMA
Authors: KAPLAN Ceren , ATAŞ Cafer , KARABULUT Barış
Published: January 2024

Bu çalışmanın amacı, çocuk diş kliniğine başvuran 4-12 yaş aralığındaki çocuklarda tespit edilen dental anomalilerin ve patolojilerin sıklığını, cinsiyete ve yerlerine göre dağılımlarını belirlemektir. 1 yıl içinde pedodonti kliniğine başvuran 4-12 yaş aralığında 3112 hastanın panoramik radyografileri, dental anomali ve patolojik lezyon açısından retrospektif olarak incelenmiştir. Dental anomaliler; sayı, boyut, biçim ve durum anomalilerinin alt başlıklarına göre sınıflandırılmıştır. Elde edilen veriler; cinsiyet, yaş grupları ve çenelere göre sınıflandırılarak ilişkileri istatiksel olarak değerlendirilmiştir. Çalışmaya dahil olan 4-12 yaşları arasındaki hastaların; 1504'ü kız (%48.3) ve 1608'i erkektir (%51.7). Dental anomali ve patolojik lezyon prevalansı; erkek çocuklarında daha yüksektir. En yüksek vaka prevalansı 10 yaş erkek çocuklarında (%1.24) görülürken; en düşük vaka prevalansı 4 yaş kız çocuklarında (%0.20) tespit edilmiştir. Kız çocuklarında; maksilladaki mikrodonti ve mandibuladaki hipodonti bulguları istatistiksel olarak anlamlı derecede yüksek bulunmuştur. Erkek çocuklarda ise; maksillada hiperdonti, mandibulada patolojik lezyon bulguları anlamlı şekilde yüksek tespit edilmiştir. 10 yaş grubunda erkek çocuklarda görülen hipodonti, dental anomali ve patolojik lezyonlar kız çocuklarına göre istatiksel olarak yüksek bulunmuştur (p
EDUKASI DAN SKRINING DIABETES MELITUS PADA REMAJA DI RONGTENGAH SAMPANG MADURA
Authors: Purwaningsih Nur Vita , Kunsah Baterun , Maulidiyanti Ellies Tunjung Sari , Widyastuti Rahma , Saputro Tri Ade , Rahmawati Rinza , Nuzula Firdausi Nuzula
Published: January 2024

Diabetes mellitus is a heterogeneous group of disorders characterized by hyperglycemia resulting from absolute or relative deficits in insulin production or action. The increase in non-communicable diseases, one of which is diabetes mellitus. Diabetes mellitus in adolescents occurs at age ≥ 15 years. So to reduce the risk of early non-communicable diseases in adolescents, pro-health behavior is needed from adolescence through early detection. The aim of this activity is to increase understanding among teenagers about the dangers of diabetes mellitus so that they can adopt a healthy lifestyle and recognize early detection methods that can be used to prevent the disease. The method used in this community service activity is a presentation and discussion about the dangers of diabetes mellitus. To measure the level of participants' understanding regarding the dangers of diabetes mellitus, a pretest and posttest were carried out at the end of the activity. This activity was attended by 35 participants, namely teenagers aged 17-20 years in Rongtengah Sampang Madura. The average pretest score was 53.7 points, while the average posttest score was 72.3 points. These results indicate that there has been an increase in public knowledge about the meaning, risk factors, symptoms and ways to prevent diabetes mellitus. It is hoped that educational activities can be sustainable so that teenagers can apply ways to prevent diabetes mellitus
EFEKTIVITAS EDUKASI DAN PELATIHAN SENAM KAKI PADA IBU HAMIL DENGAN DIABETES MELITUS
Authors: Listiana Eka , Fahmi Faradisa Yuanita , Munawaroh Siti , Rini Sri Hesthi Sonyo
Published: January 2024

Abstract: Gestational diabetes mellitus (GDM) is a condition of glucose intolerance in pregnant women who have not previously been diagnosed with diabetes mellitus, resulting in an increase in blood sugar levels during pregnancy (Allehdan, 2019). Gestational diabetes mellitus is a common pregnancy complication and can only be diagnosed at a gestational age of more than 20 weeks. Pregnant women with Miletus diabetes are at risk of gaining weight rapidly and generally also experience complications during the delivery process and are at risk of giving birth to babies with excess weight (macrosomia), giving birth to premature babies or physical disabilities. The American College of Obstetricians and Gynecologists (ACOG) stated that in 2019 it was reported that 86% of pregnancies had diabetes complications, of which 7% were gestational diabetes mellitus (Ningsih, 2019). Efforts can be made to overcome this problem through education and training pregnant women to do diabetes foot exercises. This education aims to increase knowledge and awareness of pregnant women and help pregnant women do exercise, especially gymnastics, to prevent complications of diabetic feet (Amiri, 2021). This community service was carried out at Puri Jatisari Permai Kaliwungu by 15 pregnant women at Puri Jatisari Permai Kaliwungu. This service activity was carried out by 4 lecturers and 5 students. The results show that there are differences in pregnant women's knowledge before and after education. In addition, there is an increase in skills both during training and after training. The need for monitoring and follow-up on activities in the community.
THE GRADIENT AND PARTIAL DERIVATIVES OF BICOMPLEX NUMBERS: A COMMUTATIVE-QUATERNION APPROACH
Authors: ATASOY Ali
Published: January 2024

The study of bicomplex numbers, specifically commutative-quaternions, offers a fascinating exploration into the properties of complexified quaternions with commutative multiplication. Understanding the gradient and partial derivatives within this mathematical framework is crucial for analyzing the behavior of bicomplex functions. Real quaternions are not commutative but bicomplex numbers are commutative by multiplication. Bicomplex numbers are the special case of real quaternions. In this study, gradient and partial derivatives are obtained for bicomplex number valued functions.
En el club Silencio
Authors: Ferrer Roger
Published: January 2024

Una de las secuencias más características de David Lynch retrata a algún personaje observando o actuando en un escenario, o algo similar a uno. La secuencia se repite en casi todas sus películas. Tanta reiteración con el motivo predilecto de Lynch, ese escenario al que eternamente retorna, invita al analista a interrogase por las razones de tal obstinación. El artículo ofrece respuestas a ese interés del cineasta, basado en cuatro razones: como recuperación de la idea barroca del teatro del mundo, como lugar de satisfacción de los deseos, como autorreflexión sobre los dispositivos cinematográficos y como reflexión metafísica. En este último sentido, se expondrá el tipo de mentalidad o el horizonte cultural que ha influido en Lynch y cómo puede haberle dejado tal huella, basado en su práctica de Meditación Trascendental
Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma
Authors: Scadding G. K. , McDonald M. , Backer V. , Scadding G. , Bernal-Sprekelsen M. , Conti D. M. , De Corso E. , Diamant Z. , Gray C. , Hopkins C. , Jesenak M. , Johansen P. , Kappen J. , Mullol J. , Price D. , Quirce S. , Reitsma S. , Salmi S. , Senior B. , Thyssen J. P. , Wahn U. , Hellings P. W.
Published: January 2024

Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.
Post-transplant diabetes mellitus: risk factors and outcomes in a 5-year follow-up
Authors: Rossi Matheus Rizzato , Mazzali Marilda , de Sousa Marcos Vinicius
Published: January 2024

Introduction

Kidney transplantation is associated with an increased risk of posttransplant diabetes mellitus (PTDM), impacting recipient and graft survivals. The incidence of PTDM ranges from 15% to 30%, with most cases occurring in the first year post-transplant. Some clinical and laboratory characteristics pre- and post-transplant may be associated with a higher PTDM incidence in a more extended follow-up period. This study aimed to analyze the prevalence of PTDM among renal transplant recipients without previous DM diagnosis during a five-year post-transplant follow-up, as well as clinical and laboratory characteristics associated with a higher incidence of PTDM during this period.

Material and methods

Single-center retrospective cohort including kidney transplant recipients older than 18 years with a functioning graft over six months of follow-up between January and December 2018. Exclusion criteria were recipients younger than 18 years at kidney transplantation, previous diabetes mellitus diagnosis, and death with a functioning graft or graft failure within six months post-transplant.

Results

From 117 kidney transplants performed during the period, 71 (60.7%) fulfilled the inclusion criteria, 18 (25.3%) had PTDM diagnosis, and most (n=16, 88.9%) during the 1st year post-transplant. The need for insulin therapy during the hospital stay was significantly higher in the PTDM group (n=11, 61.1% vs. n=14, 26.4%, PTDM vs. non-PTDM). Other PTDM risk factors, such as older age, high body mass index, HLA mismatches, and cytomegalovirus or hepatitis C virus infections, were not associated with PTDM occurrence in this series. During 5-year post-transplant follow-up, the graft function remained stable in both groups.

Conclusion

The accumulated incidence of PTDM in this series was similar to the reported in other studies. The perioperative hyperglycemia with the need for treatment with insulin before hospital discharge was associated with PTDM.
Advances, gaps and way forward in provision of climate services over the Greater Horn of Africa
Authors: Gudoshava Masilin , Otieno George , Koech Eunice , Misiani Herbert , Ongoma Jemimah Gacheru , Heinrich-Mertsching Claudio , Wachana Calistus , Endris Hussen Seid , Mwanthi Anthony , Kilavi Mary , Mwangi Emmah , Colman Andrew , Parker Douglas , Mutemi Joseph Nzau , Machio Paula , Omay Paulino Omoj , Ombai Paul , Anande Doreen , Kondowe Alfred , Mugume Isaac , Ayabagabo Prosper , Houssein Houda Youssouf , Waiss Mahado Salah , Abeshu Bekele , Kayoya Ezechiel , Sharawe Mohamud Nor , Bahaga Titike , Todd Martin , Segele Zewdu , Atheru Zachary , Artan Guleid
Published: January 2024

The Greater Horn of Africa is prone to extreme climatic conditions, thus, making climate services increasingly important in supporting decision-making processes across a range of climate sensitive sectors. This study aims to provide a comprehensive review of the recent advances, gaps and challenges in the provision of climate services over the region, for each of the components of the Global Framework for Climate Services. The study explores various milestones that have been achieved toward climate service delivery. The achievements include improvement of station network coverage, and enhancing the capacity of member states to utilize various tools in data analysis and generate routine climate products. The advancement in science, and availability of High-Performance Computing has made it possible for forecast information to be provided from nowcasting to seasonal timescales. Moreover, operationalizing of the objective forecasting method for monthly and seasonal forecasts has made it possible to translate tercile forecasts for applications models. Additionally, innovative approaches to user engagement through co-production, communication channels, user-friendly interfaces, and dissemination of climate information have also been developed. Despite the significant progress that has been made in the provision of climate services, there are still many challenges and gaps that need to be overcome in order to ensure that these services are effectively meeting the needs of users. The research of the science underpinning climate variability, capacity building and stakeholder engagement, as well as improved data management and quality control processes are some of the gaps that exist over the region. Additionally, communication and dissemination of climate information, including timely warnings and risk communication, require improvement to reach diverse user groups effectively. Addressing these challenges will require strengthened partnerships, increased investment in capacity building, enhanced collaboration between the climate information producers and stakeholders, and the development of user-friendly climate products. Bridging these gaps will foster greater resilience to climate-related hazards and disasters in the Greater Horn of Africa and support sustainable development in the region.
Incomplete lineage sorting and long-branch attraction confound phylogenomic inference of Pancrustacea
Authors: Yu Hiu Yan , Chu Ka Hou , Tsang Ling Ming , Ma Ka Yan
Published: January 2024

Introduction

The phylogenetic relationships within Pancrustacea (including Crustacea and Hexapoda) remain elusive despite analyses using various molecular data sets and analytical approaches over the past decade. The relationship between the major lineages of Allotriocarida, which includes Hexapoda, the most species-rich animal taxon, is particularly recalcitrant.

Methods

To investigate and resolve the root of phylogenetic ambiguity in Pancrustacea, we re-evaluated the evolutionary relationships of major pancrustacean clades using a phylogenetically informed orthology approach and assessed the effect of systematic errors, with a major focus on long branch attraction (LBA) and incomplete lineage sorting (ILS). A data set comprising 1086 orthologs from 106 species representing all major extant classes of pancrustaceans was assembled and used in gene tree and species tree construction after various filtering processes.

Results and discussion

Regardless of the filtering criteria and phylogenetic analyses, the resulting trees consistently supported (1) a sister relationship of Remipedia and Hexapoda (hence rejecting the monophyly of Xenocarida, i.e. Remipedia + Cephalocarida), and (2) refuted the monophyly of Multicrustacea, as Copepoda is either sister to or nested within Allotriocarida. Examination of gene trees reveals that the grouping of Multicrustacea and Xenocarida in previous phylogenetic studies may represent LBA artefacts. Phylogenetic signal analyses suggest a low resolution and an incidence of strong conflicting signals at the deep splits. Further analyses indicate a partial contribution of incomplete lineage sorting (ILS) to the contradictory signal in the allotriocaridan phylogeny, leading to limited support for any potential relationships between Branchiopoda, Cephalocarida and Copepoda. This study suggests the need for further examination of other potential sources of signal discordance, such as introgression and gene tree estimation error to fully understand the evolutionary history of Pancrustacea.
Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma
Authors: Rezagholizadeh Fereshteh , Tajik Fatemeh , Talebi Morteza , Taha Seyed Reza , Shariat Zadeh Mahdieh , Farhangnia Pooya , Hosseini Hamideh Sadat , Nazari Aram , Mollazadeh Ghomi Shabnam , Kamrani Mousavi Seyede Mahtab , Haeri Moghaddam Niloofar , Khorramdelazad Hossein , Joghataei Mohammad Taghi , Safari Elahe
Published: January 2024

Introduction

Pancreatic cancer is a truculent disease with limited treatment options and a grim prognosis. Immunotherapy has shown promise in treating various types of cancer, but its effectiveness in pancreatic cancer has been lacking. As a result, it is crucial to identify markers associated with immunological pathways in order to improve the treatment outcomes for this deadly cancer. The purpose of this study was to investigate the diagnostic and prognostic significance of three markers, CD8, CD68, and VISTA, in pancreatic ductal adenocarcinoma (PDAC), the most common subtype of pancreatic cancer.

Methods

We analyzed gene expression data from Gene Expression Omnibus (GEO) database using bioinformatics tools. We also utilized the STRING online tool and Funrich software to study the protein-protein interactions and transcription factors associated with CD8, CD68, and VISTA. In addition, tissue microarray (TMA) and immunohistochemistry (IHC) staining were performed on 228 samples of PDAC tissue and 10 samples of normal pancreatic tissue to assess the expression levels of the markers. We then correlated these expression levels with the clinicopathological characteristics of the patients and evaluated their survival rates.

Results

The analysis of the GEO data revealed slightly elevated levels of VISTA in PDAC samples compared to normal tissues. However, there was a significant increase in CD68 expression and a notable reduction in CD8A expression in pancreatic cancer. Further investigation identified potential protein-protein interactions and transcription factors associated with these markers. The IHC staining of PDAC tissue samples showed an increased expression of VISTA, CD68, and CD8A in pancreatic cancer tissues. Moreover, we found correlations between the expression levels of these markers and certain clinicopathological features of the patients. Additionally, the survival analysis revealed that high expression of CD8 was associated with better disease-specific survival and progression-free survival in PDAC patients.

Conclusion

These findings highlight the potential of CD8, CD68, and VISTA as diagnostic and prognostic indicators in PDAC.
The effects of NDM-5 on Escherichia coli and the screening of interacting proteins
Authors: Li Lin , Gao Yiming , Wang Longbo , Lu Fang , Ji Qianyu , Zhang Yanfang , Yang Shuo , Cheng Ping , Sun Feifei , Qu Shaoqi
Published: January 2024

Carbapenem-resistant Escherichia coli (E. coli) strains are widely distributed and spreading rapidly, creating significant challenges for clinical therapeutics. NDM-5, a novel mutant of New Delhi Metallo-β-Lactamase-1 (NDM-1), exhibits high hydrolase activity toward carbapenems. Since the genetic backgrounds of clinically isolated carbapenem-resistant E. coli are heterogeneous, it is difficult to accurately evaluate the impact of blaNDM–5 on antibiotic resistance. Herein, E. coli BL21 was transformed with a plasmid harboring blaNDM–5, and the resultant strain was named BL21 (pET-28a-blaNDM–5). Consistent with the findings of previous studies, the introduction of exogenous blaNDM–5 resulted in markedly greater resistance of E. coli to multiple β-lactam antibiotics. Compared with BL21 (pET-28a), BL21 (pET-28a-blaNDM–5) exhibited reduced motility but a significant increase in biofilm formation capacity. Furthermore, transcriptome sequencing was conducted to compare the transcriptional differences between BL21 (pET-28a) and BL21 (pET-28a-blaNDM–5). A total of 461 differentially expressed genes were identified, including those related to antibiotic resistance, such as genes associated with the active efflux system (yddA, mcbR and emrY), pili (csgC, csgF and fimD), biofilm formation (csgD, csgB and ecpR) and antioxidant processes (nuoG). Finally, the pGS21a plasmid harboring blaNDM–5 was transformed into E. coli Rosetta2, after which the expression of the NDM-5 protein was induced using isopropyl-β-D-thiogalactoside (IPTG). Using glutathione-S-transferase (GST) pull-down assays, total proteins from E. coli were scanned to screen out 82 proteins that potentially interacted with NDM-5. Our findings provide new insight into the identified proteins to identify potential antibiotic targets and design novel inhibitors of carbapenem-resistant bacteria.