bluuebunny/crossref_metadata_2025 huggingface dataset:
Co-Working Spaces in Greece During the COVID-19 Era
Authors: Papavasileiou Angelos , Mitoula Roido , Kaldis Panagiotis E. , Papagrigoriou Aristidis
Published: October 2022

The organization of space and working time, especially their location and geography, is a significant concern to researchers and politicians. However, in today's globalized economy and online age, the way we work and the workplace's whole location and geography are being redefined and researched. This paper investigates the current situation of co-working spaces in Greece, and the authors further analyse the case study of the Athens municipality. They examined views on new workplaces satisfaction and the benefits of the location. The research also explored the factors influencing ‘co-working spaces' satisfaction and views on the location's benefits. Finally, there is a detailed record of the areas in question throughout the territory, and they are scattered and concentrated in certain areas. Their characteristics are then explored, and policies and actions are proposed for their operation and development in the post-COVID-19 era.
Modify Symmetric Fuzzy Approach to Solve the Multi-Objective Linear Fractional Programming Problem
Authors: Nawkhass Maher Ali , Sulaiman Nejmaddin Ali
Published: October 2022

The property of fuzzy sets is approached as an instrument for the construction and finding of the value of the multi-objective linear fractional programming problem (MOLFPP), which is one of the systems of decision problems that are covered by fuzzy dealings. The paper introduces an approach to convert and solve such a problem by modifying the symmetric fuzzy approach, suggesting an algorithm, and demonstrating how the fuzzy linear fractional programming problem (FLFPP) can be answered without raising the arithmetic potency. Also, it introduces a technique that uses an optimal mean to convert MOLFPP to a single LFPP by modifying the symmetric fuzzy approach. A numeric sample is provided to clarify the qualification of the suggested approach and compare the results with other techniques, which are solved by using a computer application to test the algorithm of the above method, indicating that the results obtained by the fuzzy environment are promising.
Influence of Load and Speed on Tribological Performance of A390 and A515 Alloys in Dry Sliding Behavior A Comparative Study
Authors: Lal Basant , Dey Abhijit , Anwar Mufti Taseer
Published: October 2022

In this study, tribological characteristics and wear debris morphology of A390 and A515 alloys are evaluated and compared. Components with a high wear resistance slide are typically made with alloys are A390 and A515, while components with high hardness requirements are usually made up with SS410. Those alloys were used in brake pads, and SS410 steel is used for the brake disc. Speed and pad force are the two factors that affect tribological characteristics such as friction coefficient and wear rate. Wear debris and wear track were examined by scanning election microscopy and optical microscope, respectively. The effect of sliding speed variations on wear and friction coefficient at various load conditions was also evaluated, and a comparative analysis was reported based on wear rates, coefficient of friction, and debris morphology for both materials. The A515 alloys shows higher friction coefficient under all the process conditions except at very low loads and high speeds due to increased superficial hardness and the composition of the case layer (oxygen-diffused/oxide formed).
Home Automation and Application With Bolt IoT
Authors: Kakne Ashish Sudhir , Chouragade P. M.
Published: October 2022

Even with advancement of communications technologies, home automation and application have received major attention. Today's digital world is mostly reliant on the internet so that there is a need to design such a solution to make more efficient from unauthorized components to safeguard the data that may work in wireless mode alone. This system provides guidance towards operational operations specifically surveillance on the areas and its structure and managing assets over the internet utilizing web applications employing IoT techniques. Home automation is a vital unit which must meet the main criteria like user interface and safety. In the current situation, the complete process depends on the Bolt IoT platform, a home automation system where it can access and manage house devices remotely from anywhere. The user may use this system to operate different equipment like LEDs, fans, or DC motors as well as to keep an eye on the environment's temperature. In addition, the Bolt IoT module enables cloud connectivity to the system, and sensor data is communicated to the cloud.
Development and Evaluation of Two 3D-Simulated Practice Learning Environments
Authors: Farrier Stephen , Connolly Thomas M. , Tsvetkova Nikolina , Soflano Mario , Papadopoulos Petros
Published: October 2022

This paper discusses the evaluation of two 3D simulated practice learning environments, Tiny Oaks and Play2Do, focused on supporting people working with children, families, and vulnerable people in special educational settings. Pre-test/post-test evaluation methodology was employed consisting of a questionnaire with 16 questions covering knowledge and understanding, professional practice, and transferable skills. Tiny Oaks had 530 participants pre-test and 423 post-test from six European countries, and results show a significant increase in learning across all questions. Play2Do had 318 participants pre-test and 301 participants post-test from the UK and Bulgaria, and again results show a significant increase in learning across all questions. The system usability scale (SUS) questionnaire was also used to measure the usability of the two environments, and usability was found to be excellent. Findings suggest that 3D simulated practice environments can provide a valuable learning experience and can provide practice learning scenarios that may be difficult to encounter in real-life.
Aspects of the biology of Phlebotomus argentipes (Diptera: Psychodidae) in Kurunegala district
Authors: Nayakarathna N.M.N.G. , Gunathilaka R.A.K.M. , Ganehiarachchi G.A.S.M.
Published: October 2022

The sand fly species Phlebotomus argentipes is reported to be the suspected primary vector of leishmaniasis in Sri Lanka transmitting Leishmania donovani which causes visceral leishmaniasis. Thus, studies about some aspects of the reproductive biology of P. argentipes and the performances of immature stages are highly important for adopting control measures. Accordingly, sand flies were captured from the wild using five CDC light traps set in pre-identified places in the Kurunegala district. Gravid and fully engorged females were sorted out and they were directly placed for oviposition in plaster of Paris lined pots. The unengorged ones were allowed to feed on a mouse and placed for oviposition in similar pots. The rate of oviposition, egg hatching, and adult emergence was determined by making daily observations. Moreover, the duration of eggs, each larval instar, pupae, and adult longevity were recorded. According to the observations the life cycle of P. argentipes lasted about 3 to 4 months. The eggs were laid 10-13 days after the blood meal, and they hatched after 12-16 days. Similarly, each second instar, third instar, fourth instar and pupae spent 12-16 days for the emergence. However, the pupal duration was 8-10 days. Furthermore, the rate of oviposition was 15.8 per female and egg hatching and adult emergence was 62.52% and 52.32% respectively. The longevity of the emerged adults was 8-15 days. The information presented on P. argentipes in this study is highly important to initiate and maintain a sand fly colony under laboratory conditions for the implementation of successful control measures.
Microbiology and infectious diseases in times of crisis
Authors: Liyanapathirana Veranja
Published: October 2022

No abstract available
Review of Internet of Things-Based Artificial Intelligence Analysis Method through Real-Time Indoor Air Quality and Health Effect Monitoring: Focusing on Indoor Air Pollution That Are Harmful to the Respiratory Organ
Authors: Mun EunMi , Cho Jaehyuk
Published: October 2022

Everyone is aware that air and environmental pollutants are harmful to health. Among them, indoor air quality directly affects physical health, such as respiratory rather than outdoor air. However, studies that have examined the correlation between environmental and health information have been conducted with public data targeting large cohorts, and studies with real-time data analysis are insufficient. Therefore, this research explores the research with an indoor air quality monitoring (AQM) system based on developing environmental detection sensors and the internet of things to collect, monitor, and analyze environmental and health data from various data sources in real-time. It explores the usage of wearable devices for health monitoring systems. In addition, the availability of big data and artificial intelligence analysis and prediction has increased, investigating algorithmic studies for accurate prediction of hazardous environments and health impacts. Regarding health effects, techniques to prevent respiratory and related diseases were reviewed.
Scientific basis of Canada's first public national seismic risk model
Authors: Hobbs T E , Journeay J M , Rao A S , Martins L , LeSueur P , Kolaj M , Simionato M , Silva V , Pagani M , Johnson K , Rotheram D
Published: October 2022

Natural Resources Canada, in partnership with the Global Earthquake Model Foundation, has prepared a public Canadian Seismic Risk Model to support disaster risk reduction efforts across industry and all levels of government, and to aid in Canada's adoption of the
Sendai Framework for Disaster Risk Reduction. Developing this model has involved the creation of a national exposure inventory, Canadian specific fragility and vulnerability curves, and adjustment of the Canadian Seismic Hazard Model which forms the basis for the seismic provisions of the National
Building Code of Canada. Using the Global Earthquake Model Foundation's OpenQuake Engine (OQ), risk modelling is completed using both deterministic and probabilistic risk calculations, under baseline and simulated retrofit conditions. Output results are available in all settled regions of Canada, at
the scale of a neighbourhood or smaller. We report on expected shaking damage to buildings, financial losses, fatalities, and other impacts such as housing disruption and the generation of debris. This paper documents the technical details of the modelling approach including a description of novel
datasets in use, as well as preliminary results for a magnitude 9.0 earthquake on the Cascadia megathrust and nation-wide 500 year expected probabilistic losses. These kinds of results, such as earthquake scenario impacts, loss exceedance curves, and annual average losses, provide a quantitative
base of evidence for decision making at local, regional, and national levels.
Dermoscopy of Cutaneous and Palmar Lichen Nitidus
Authors: Dave Jayati Shailesh , Mahajan Sunanda Arun , Oswal Prateek
Published: October 2022

Lichen nitidus (LN) is a relatively uncommon chronic cutaneous lichenoid group of disease characterized by tiny quintessentially discrete hypopigmented to skin coloured papules commonly seen over dorsa of hands/forearms, lower abdomen, penis, and buttocks. The cutaneous manifestation of a disease on palms/soles varies from their presentation on body, which makes it difficult to diagnose at times. A 23-year-old healthy female presented with mildly itchy lesions on bilateral wrist, fingers, elbows, peri-umbilical area, and left palm since 6 months. On dermoscopy, we could appreciate the classical described findings of LN which were confirmed on histopathology. LN has a characteristic dermoscopic features, which come to rescue for diagnosis and also avoid a biopsy. We describe a rare presentation of palmar LN with two different morphologies along with classical cutaneous distribution of LN and their dermoscopy.
Graham-Little-Piccardi-Lassueur Syndrome—A Rare Case Report with Concomitant Lichen Planus Pigmentosus and Oral Lichen Planus in a Pregnant Female
Authors: Patokar Abhishek S. , Khandait Gaurav H. , Chaudhari Nitin , Khatu Swapna S.
Published: October 2022

Graham-Little-Piccardi-Lassueur syndrome is a rare variant of lichen planopilaris. It is characterized by multifocal, patchy, cicatricial alopecia of the scalp, noncicatricial alopecia of axilla and pubic region, and keratotic follicular papules involving the trunk and extremities. Trichoscopy shows perifollicular erythema, tubular perifollicular scales, fibrotic white dots, and hair casts along the hair shafts. We are reporting this rare syndrome in a 26-year-old pregnant woman with concomitant oral lichen planus and lichen planus pigmentosus. This case is unique as no previous report of coexistence of these variants of lichen planus has been published.
Linear Porokeratotic Adnexal Ostial Nevus with Dermoscopic Features
Authors: Mahajan Sunanda Arun , Kabbannavar Yallappa Ramachandrappa , Singh Surender
Published: October 2022

Porokeratotic adnexal ostial nevus is a rare nevoid condition, with a characteristic histological feature of coronoid lamella involving the acrosyringium and the hair follicle. Here we report a case of an 11-year-old female child presented with multiple hyperpigmented and hyperkeratotic papules present over the posterior aspect of right lower extremities along Blaschko’s lines.
Histopathological Aneurysmal Variant of Dermatofibroma—A Rare Entity Known for Malignant Appearance and Recurrence
Authors: Gitte Dhanraj V. , Ghate Smita S. , Dhurat Rachita S. , Pai Suraj U.
Published: October 2022

Dermatofibroma is one of the most common dermal dermatologic tumors. In its classic variant, a dermatofibroma is easily recognized by dermatologists; however, studies have identified numerous variants of the dermatofibroma that do not present with a classic clinical picture. Aneurysmal fibrous histiocytoma, one of these variants, is not easily recognized because of its rarity and potentially malignant appearance. Microscopically, aneurysmal fibrous histiocytoma displays some similarities to a classic dermatofibroma along with distinguishing characteristics, such as blood-filled pseudovascular spaces. Aneurysmal fibrous histiocytoma is a benign lesion with a risk for recurrence if not adequately excised. In this case, we present this rare histological variant of dermatofibroma that stimulates clinically other malignant lesions.
Usefulness of BRAF VE1 immunohistochemistry in non–small cell lung cancers: a multi-institutional study by 15 pathologists in Korea
Authors: Chang Sunhee , Choi Yoon-La , Shim Hyo Sup , Lee Geon Kook , Ha Seung Yeon ,   Korean Cardiopulmonary Pathology Study Group
Published: October 2022

Background: Next-generation sequencing (NGS) is an approved test to select patients for BRAF V600E targeted therapy in Korea. However, the high cost, long turnaround times, and the need for sophisticated equipment and skilled personnel limit the use of NGS in daily practice. Immunohistochemistry (IHC) is a rapid and relatively inexpensive assay available in most laboratories. Therefore, in this study, we evaluate the usefulness of BRAF VE1 IHC in terms of predictive value and interobserver agreement in non–small cell lung cancers (NSCLCs). Methods: A total of 30 cases with known BRAF mutation status were selected, including 20 cases of lung adenocarcinomas, six cases of colorectal adenocarcinomas, and four cases of papillary thyroid carcinomas. IHC for BRAF V600E was carried out using the VE1 antibody. Fifteen pathologists independently scored both the staining intensity and the percentage of tumor cell staining on whole slide images. Results: In the lung adenocarcinoma subset, interobserver agreement for the percentage of tumor cell staining and staining intensity was good (percentage of tumor cell staining, intraclass correlation coefficient = 0.869; staining intensity, kappa = 0.849). The interobserver agreement for the interpretation using the cutoff of 40% was almost perfect in the entire study group and the lung adenocarcinoma subset (kappa = 0.815). Sensitivity, specificity, positive predictive value, and negative predictive value of BRAF VE1 IHC were 80.0%, 90.0%, 88.9%, and 81.8%, respectively. Conclusions: BRAF VE1 IHC could be a screening test for the detection of BRAF V600E mutation in NSCLC. However, further studies are needed to optimize the protocol and to establish and validate interpretation criteria for BRAF VE1 IHC.
A clinicopathologic and immunohistochemical study of primary and secondary breast angiosarcoma
Authors: Abada Evi , Jang Hyejeong , Kim Seongho , Ali-Fehmi Rouba , Bandyopadhyay Sudeshna
Published: October 2022

Background: We aimed to study the clinicopathologic and immunohistochemical (IHC) (CD117, c-Myc, and p53) characteristics, and overall survival of primary and secondary breast angiosarcoma (BAS). Methods: This was a retrospective study of BAS cases diagnosed between 1997 and 2020 at our institution. Hematoxylin and eosin-stained slides were reviewed for tumor morphology, margin status, and lymph node metastasis. CD117, p53, D2-40, CD31, and c-Myc IHC stains were performed on 11 viable tissue blocks. Additional clinical information was obtained from the electronic medical records. Results: Seventeen patients with BAS were identified. Of these, five (29%) were primary and 12 (71%) were secondary BAS, respectively. The median age at diagnosis for primary BAS was 36 years. The median age at diagnosis for secondary BAS was 67 years. The median time to secondary BAS development following radiotherapy was 6.5 years (range, 2 to 12 years). There was no significant difference between primary and secondary BAS in several histopathologic parameters examined, including histologic grade, necrosis, mitotic count, lymph node metastasis, and positive tumor margins. There was also no difference in CD117, p53, D2-40, CD31, and c-Myc expression by IHC between primary and secondary BAS. During a median followup of 21 months, primary BAS had two (40%) reported deaths and secondary BAS had three (25%) reported deaths. However, this difference in survival between both groups was not statistically significant (hazard ratio, 0.51; 95% confidence interval, 0.09 to 3.28; p = .450). Conclusions: BAS is a rare and aggressive disease. No histologic, IHC (CD117, c-Myc, and p53), or survival differences were identified between primary and secondary BAS in this study.
Current status of cytopathology practice in Korea: impact of the coronavirus pandemic on cytopathology practice
Authors: Hong Soon Auck , Jung Haeyoen , Kim Sung Sun , Jin Min-Sun , Pyo Jung-Soo , Jeong Ji Yun , Choi Younghee , Gong Gyungyub , Chong Yosep ,   The Committee of Quality Improvement of Korean Society for Cytopathology
Published: October 2022

Background: The Continuous Quality Improvement program for cytopathology in 2020 was completed during the coronavirus pandemic. In this study, we report the result of the quality improvement program. Methods: Data related to cytopathology practice from each institute were collected and processed at the web-based portal. The proficiency test was conducted using glass slides and whole-slide images (WSIs). Evaluation of the adequacy of gynecology (GYN) slides from each institution and submission of case glass slides and WSIs for the next quality improvement program were performed. Results: A total of 214 institutions participated in the annual cytopathology survey in 2020. The number of entire cytopathology specimens was 8,220,650, a reduction of 19.0% from the 10,111,755 specimens evaluated in 2019. Notably, the number of respiratory cytopathology specimens, including sputum and bronchial washing/ brushing significantly decreased by 86.9% from 2019, which could be attributed to the global pandemic of coronavirus disease. The ratio of cases with atypical squamous cells to squamous intraepithelial lesions was 4.10. All participating institutions passed the proficiency test and the evaluation of adequacy of GYN slides. Conclusions: Through the Continuous Quality Improvement program, the effect of coronavirus disease 2019 pandemic, manifesting with a reduction in the number of cytologic examinations, especially in respiratory-related specimen has been identified. The Continuous Quality Improvement Program of the Korean Society for Cytopathology can serve as the gold standard to evaluate the current status of cytopathology practice in Korea.
Vulnerability methods in hard rock formation as a basis for groundwater risk assessment – from resource to source
Authors:   Faculty of Mining and Geology, University of Belgrade, Serbia, Živanović Vladimir , Jemcov Igor ,   Faculty of Mining and Geology, University of Belgrade, Serbia, Dragišić Veselin ,   Faculty of Mining and Geology, University of Belgrade, Serbia
Published: October 2022

Groundwater in a hard rock formation is most endangered at places where a potential source can discharge contaminants that can reach the saturated zone of an aquifer. In these circumstances, an essential tool for groundwater protection is the contamination risk map. This map is based on the integration of two maps: a hazards map, i.e., map of potential sources of contamination and a vulnerability map. The selection of a proper vulnerability method is an important task since the resulting vulnerability map can significantly impact the final risk of contamination map. The most appropriate method for groundwater vulnerability assessment was considered in the case study of Tara National park, in Western Serbia. The four commonly used methods were applied to assess the intrinsic vulnerability maps: DRASTIC, EPIK, PI and COP. All the applied methods resulted in different vulnerability maps in assessing the degree of vulnerability, consequently influencing the groundwater contamination risk maps. The applied research presents an example of how contamination risk should be assessed in a specific area. Comparison of the results obtained for the area of Tara National Park indicates the preference of the PI method as a well-balanced method, taking into account all the specifics of the study area. A detailed analysis of the assessed risks in the catchments of the existing sources was also conducted to indicate probable sources of contamination and confirm the degree of accuracy of the created vulnerability and risk maps. The conducted research emphasizes the necessity to adopt a clear conceptual hydrogeological model and to apply several methods simultaneously to determine the optimal one for each individual area.
The calcareous nannofossil record of the uppermost Maastrichtian-lower Palaeocene in the Kırıkkale Basin, in the Central Anatolian Region (Turkey)
Authors:   Yozgat Bozok University, Faculty of Engineering-Architecture, Geological Engineering Department, Turkey, Kaya Ozer Caner , Kilic Yakup ,   Yozgat Bozok University, Graduate Education Institute, Divanlı Road, Yozgat, Turkey
Published: October 2022

The Late Cretaceous–Early Paleogene (K–Pg) was a critical period of transition in geological time. This period encompassed short-term climatic fluctuations on a global scale, changes in ocean circulation, and sudden and large extinctions of marine and terrestrial organisms. In the study area, located in the mid to low latitudes, the Late Cretaceous and Early Paleogene were very tectonically active due to the positioning of the site close to the collision zone of two large continents. The impacts of the global K–Pg crisis can be observed in the study area. In this study, the calcareous nannofossil contents of late Maastrichtian–Danian sediments were studied, and the nannofossil biostratigraphy determined, from samples from the Samanlık and Dizilitaşlar Formations, deposited in the Kırıkkale Basin. From three stratigraphic sections, 26 nannofossil genera and 36 nannofossil species were identified from the Late Maastrichtian UC20aTP and UC20bTP biozones and the NP1 and NP2 biozones of the Danian. Additionally, it was determined that the K–Pg boundary was not continuous in the study area. In the Kırıkkale Basin, relatively low abundances of Micula decussate Vekshina, 1959 signals a diagenetic effect and stressful environment in the Late Maastrichtian, whereas the relatively low abundances of Thoracosphaera operculata Bramlette & Martini, 1964, Braarudosphaera bigelowii (Gran & Braarud, 1935) Deflandre, 1947 and Futyania petalosa (Ellis & Lohmann, 1973) Varol, 1989 in the Danian assemblages indicate unstable environmental conditions and major environmental perturbations that reflect tectonic activity in the region. No nannofossils were encountered in those samples taken from turbiditic levels, which contained high proportions of sand.
Experimental demonstration of uncompressed 4K video transmission over directly modulated distributed feedback laser‐based terahertz wireless link
Authors: Kim Eon‐Sang , Moon Sang‐Rok , Sung Minkyu , Lee Joon Ki , Cho Seung‐Hyun
Published: October 2022

We demonstrate the transmission of uncompressed 4K videos over the photonics‐based terahertz (THz) wireless link using a directly modulated distributed feedback laser diode (DFB‐LD). For optical heterodyne mixing and data modulation, a DFB‐LD was employed and directly modulated with a 5.94‐Gb/s non‐return‐to‐zero signal, which is related to a 6G‐serial digital interface standard to support ultra‐high‐definition video resolution. We derived the optimal frequency of the THz carrier by varying the wavelength difference between DFB‐LD output and Tunable LD output in the THz signal transmitter to obtain the best transmission performances of the uncompressed 4K video signals. Furthermore, we exploited the negative laser‐to‐filter detuning for the adiabatic chirp management of the DFB‐LD by the intentional discrepancy between the center wavelength of the optical band‐pass filter and the output wavelength of the DFB‐LD. With the help of the abovementioned methods, we successfully transmitted uncompressed 4K video signals over the 2.3‐m wireless transmission distance without black frames induced by time synchronization error.
Diet-related complications according to the timing of enteral nutrition support in patients who recovered from out-of-hospital cardiac arrest: a propensity score matched analysis
Authors: Kim Gun Woo , Roh Young-Il , Cha Kyoung-Chul , Hwang Sung Oh , Han Jae Hun , Jung Woo Jin
Published: October 2022

Background: A proper nutritional plan for resuscitated patients is important in intensive care; however, specific nutritional guidelines have not yet been established. This study aimed to determine the incidence of diet-related complications that were affected by the timing of enteral nutrition in resuscitated patients after cardiac arrest.Methods: This retrospective and 1:1 propensity score matching study involved patients who recovered after nontraumatic, out-of-hospital cardiac arrest at a tertiary hospital. Patients were divided into an early enteral nutrition support (ENS) group and a delayed enteral nutrition support (DNS) group according to the nutritional support time within 48 hours after admission. The incidence of major clinical complications was compared between the groups.Results: A total of 46 patients (ENS, 23; DNS, 23) were enrolled in the study. There were no differences in body mass index, comorbidity, and time of cardiopulmonary resuscitation between the two groups. There were 9 patients (ENS: 4, DNS: 5) with aspiration pneumonia; 4 patients (ENS: 2, DNS: 2) with regurgitation; one patient (ENS: 0, DNS: 1) with ileus; 21 patients (ENS: 10, DNS: 11) with fever; 13 patients (ENS: 8, DNS: 5) with hypoglycemia; and 20 patients (ENS: 11, DNS: 9) with hyperglycemia. The relative risk of each complication during post-resuscitation care was no different between groups.Conclusions: There was a similar incidence of diet-related complications during post cardiac arrest care according to the timing of enteral nutrition.
‘I don’t command the equal respect as my peers’: Middle-class disability, stigma and social expectation in Ghana
Authors: Ocran Joseph
Published: October 2022

Disability spoils the identities of persons with disability and exposes them to stigma. Contrary to the belief that disability stigma is associated with the low social class position, middle-class persons with disability also experience stigma. Experiences of poor and underprivileged persons with disability are well documented but the experiences of middle-class persons with disability are often unnoticed. This study explored how middle-class persons with disability experience lowered social expectations because of their assumed vulnerability and supposed functional incompetence. Using the hermeneutic phenomenology approach, the study explored the lived experiences of 16 middle-class persons with disability who were purposively selected. Data was collected through in-depth interviews and analysed using the Interpretative Phenomenological Analysis approach. The participants shared experiences from various parts of Ghana. Middle-class persons with disability are assumed to lack physical strength, intellectual abilities, financial capacities, and relational abilities. They are, therefore, often treated with contempt. These experiences are influenced by nuances in social norms, relational factors, and personal characteristics such as social class, age, gender, type of impairment, and time of acquisition of impairment. Persons with disability are not a homogenous category of people. They are as diverse as non-disabled people are. The differences in their individual identities and social statuses must be considered in the design and implementation of social inclusion interventions and welfare policies meant to eliminate disability stigma and discrimination.
Marsyas of Pella and Phrygia
Authors: Müller Sabine
Published: October 2022

There is a lot of uncertainty about the attribution of fragments to either Marsyas of Pella or Marsyas of Philippi. This paper challenges the traditional attribution of BNJ 135–136 F 4 (mentioning Midas’chariot with the Gordian knot) to Marsyas of Philippi and argues in favor of the identification of Marsyas of Pella as the author. For ideological and propagandistic reasons, it would fit well into Marysas of Pella’s account of the roots of Argead rule in his first book. By referring to Midas, Marsyas would have been able to link his half-brother Antigonus as the contemporary governor of Phrygia not only with the legendary Phrygian king and his legacy, but also with a Macedonian logos attested by Herodotus, creating a connection between Midas and the foundation of Argead rule. According to this logos, there existed old kinship relations between Macedonians and Phrygians who used to dwell at the foot of Mt. Bermium and were called Briges. This tradition was of propagandistic value and could have served to increase the ideological value of Antigonus’satrapy and main base in the rivalry with the other Diadochs.
Again on “Heraios” Being Kujula and Some Related Problems
Authors: Sinisi Fabrizio
Published: October 2022

The question of the identity of the issuer of the so-called “Heraios”coinage is analysed, and it is proposed that these series be ascribed to Kujula Kadphises, as already suggested by some scholars. In this regard, the circulation of these coins and the connections established by their imagery are focused upon. Some possible inferences on the original location of Kujula Kadphises are discussed in the concluding part, hypothesizing a southern context different from the northern one commonly ascribed to the founder of the Kushan dynasty.
The God Pakeidas in Jerash – His Worship through Archaeological and Epgraphical Sources
Authors: Kubiak-Schneider Aleksandra , Lichtenberger Achim
Published: October 2022

The finds from the ancient city of Gerasa brought in 1930’two inscriptions dated to the second half of the 1st century CE which mention the deity called Pakeidas. The aim of this paper is to discuss Pakeidas and his relation to another god labelled Theos Arabikos worshipped in the same city. The authors make a broad Semitic overview on the etymology of the name Pakeidas looking at the West and East (Akkadian) Semitic evidence. The authors discuss the possible location of the temple dedicated to this god beneath the Cathedral. They also reexamine in the light of epigraphic sources in comparison to the Aramaic material from the Near East the function of archibomistai, cultic agents who served to this local god.
Strange Meeting at Salihiyeh: Who Discovered (or Encountered, or Identified, or Invented) Dura-Europos, and When?
Authors: James Simon
Published: October 2022

The centenary of the establishment of the Department of Classics at the University of Kraków coincides with that of the beginnings of the study of the ‘Pompeii of the Syrian Desert.’In spring 1920, British Indian soldiers digging in the ruins known as Salihiyeh overlooking the Euphrates accidentally revealed ancient paintings. Recorded by archaeologist James Henry Breasted, these discoveries would soon lead to further excavations by Franz Cumont (1922–1923), and eventually to the great Yale-French Academy expedition under Mikhail Rostovtzeff (1928–1937). By then the site was famous as ‘Dura-Europos,’giving us remarkable insights into Hellenistic Greek, Parthian, Roman, early Christian and Jewish life in the Middle East. Not the least of the discoveries related to the soldiers of Dura’s Roman garrison. This paper traces the history of the revelation—and, in part, invention—of Dura-Europos in the 1920s. It is a story of eminent scholars, but also of others who actually revealed the evidence: soldiers, both officers and men, of the armies of the British and French empires which dominated the region at the time. Today, at a time of ‘decolonisation’of scholarship, the very formulation ‘Dura-Europos’itself is a subject of contention.
NEIMARK-SACKER BIFURCATION AND CONTROL OF CHAOTIC BEHAVIOR IN A DISCRETE-TIME PLANT-HERBIVORE SYSTEM
Authors: GÜMÜŞ ÖZLEM AK , SELVAM A. GEORGE MARIA , JANAGARAJ RAJENDRAN
Published: October 2022

In this study, the dynamics of a discrete-time plant-herbivore model obtained using the forward Euler method are discussed. The existence of fixed points is investigated. A topological classification is made to examine the behavior of the positive fixed point where the plant and the herbivore coexist. In addition, the existence conditions and direction of Neimark-Sacker bifurcation of the model are investigated using bifurcation theory. Hybrid control method is applied to control the chaos caused by Neimark-Sacker bifurcation. Examples including time series figures, bifurcation figures, phase portraits and maximum Lyapunov exponent are provided to support our theoretical results.
A MATHEMATICAL MODEL TO ADDRESS OUT-OF-SCHOOL CHILDREN MENACE FOR ACTUALIZATION OF SUSTAINABLE DEVELOPMENT IN NIGERIA
Authors: AYOADE ABAYOMI AYOTUNDE , FARAYOLA PHILIP IYIOLA
Published: October 2022

The rising number of out-of-school children (OOSC) constitutes a major obstacle to growth and development in Nigeria. Despite various institutional frameworks and policy initiatives, Nigeria accounts for the highest number of OOSC worldwide with one out of every five OOSC globally residing in Nigeria. In an attempt to characterize dynamics of OOSC and how it could be tackled to fount sustainable development in Nigeria, a new mathematical model was formulated. The validity of the model was examined using some mathematical theorems and the model equilibria were derived. The inclusive schooling ratio, an analytic parameter that quantified the extent to which the rising OOSC was being tackled to fount development, was computed. The stability properties of the model were studied via stability theory of differential equations based on the derived inclusive schooling ratio. Sensitivity analysis was conducted for some major parameters following the normalized forward sensitivity index approach to examine the relative importance of the model parameters to OOSC expansion and contraction. Numerical simulation was later conducted to justify the theoretical results and the results of the simulation showed that efforts to fount development through minimization of OOSC were fruitful if the inclusive schooling ratio was greater than one otherwise the menace of OOSC persisted. The policy implication of the result is that tackling the menace of OOSC to fount sustainable development in Nigeria is a long-term process and any policies designed to pursue the course must be sustained.
MYOGLOBIN vs. HEMOGLOBIN BLOCKADE MODEL RELATED SMOKE GAS INHALATION - A COMPUTATIONAL ANALYSIS
Authors: ROTARU LUCIANA TEODORA , VARUT RENATA MARIA , TRUICU FLAVIUS , GIRNICEANU ALINA , FORTOFOIU MARIA , CONSTANTIN CRISTIAN
Published: October 2022

To identify the pattern of myoglobin compared to hemoglobin blockade by the combustion products contained in the fire smoke using computational chemistry tools. The myoglobin unavailability can be a determining factor of the severity and consequences of smoke poisoning, generating the inability of patients to attempt evacuate themselves, compromising myocardial function, leading to crush syndrome-like effects and increasing of multi-organ failure to the victims of mass burn casualties event. In this study, it was used quantum chemical calculations performed with the Gaussian program suite using DFT/B3LYP/6-311G level of theory to optimize molecular geometries, calculate the molecular electrostatic potential, and obtain the vibrational spectrum. These calculations were applied to the myoglobin and hemoglobin model, thus studying their binding to the essential components of toxic fire smoke. Comparing the structural descriptors – frontier molecular orbitals, energy difference, electric dipole moment (μ), was obtained the highest values as belonging to hydrogen cyanide (2.9), which may explain its increased reactivity, meaning strong interaction with both myoglobin and hemoglobin, followed by hydrochloric acid (1.03) and carbon monoxide (0.122). Within the framework of complex intoxication generated by the inhalation of fire smoke, myoglobin is blocked in a temporal manner and according to a very similar pattern to hemoglobin. It follows that the significant rhabdomyolysis found in these patients is due not only to hypoxemia but also to the primary unavailability of myoglobin, and myocardial damage is also multifactorial. Although slightly discussed, the calculation of different structural and geometric descriptors for hydrochloric acid reveals for hydrochloric acid high values, suggesting binding affinities comparable to those of carbon monoxide. Molecular modeling programs allow for new approaches and can identify parameters or areas of their reference that influence the management of patients intoxicated with fire smoke components.
E-Ticaretin Vergilendirilmesi Sorunsalının Vergi Mevzuatı Açısından Analizi
Authors: ÇINAR Saliha , ORGAN İbrahim
Published: October 2022

Son yıllarda yaşanan teknolojik gelişmeler, beraberinde birçok alanda yeni hizmet kollarını ortaya çıkarmıştır. Bununla birlikte ihtiyaçlar değişmiş ve “dijital çağ” olarak adlandırılan yeni döneme girilmiştir. Hızla değişen koşullara bağlı olarak ortaya çıkan, en önemli gelişmelerden biri de internet üzerinden, farklı yazılım araçları kullanılarak gerçekleştirilen elektronik ticarettir. Her yerden bir tıklama hareketiyle alışveriş yapabilme imkânı yaratan bu teknolojik yapı, insanoğluna boş zaman yaratma fırsatı sağlamaktadır.

E-ticaret ile internet aracılığıyla gerçekleştirilen alışverişlerin vergilendirilme boyutunda, yürürlükte olan yasalar açısından bakıldığında, birtakım yasal eksiklerin olduğu ve bu eksiklerin önemli problemlere yol açtığı görülmektedir. Bu problemlerin bazıları; işyeri kavramı, mükellefiyetin belirlenmesi, elde edilen kazançların niteliği gibi konulardır. Bu çalışmanın amacı; e-ticaretin vergilendirme boyutunun yürürlükte bulunan vergi kanunları açısından değerlendirilmesidir. Yapılan vergisel düzenlemelerin dijital ortamda gerçekleştirilen faaliyetler açısından yetersiz kaldığı görülmüştür.
Geographic-Time Distribution of Ambulance Calls in Singapore: Utility of Geographic Information System in Ambulance Deployment (CARE 3)
Authors: Ong Marcus EH , Ng Faith SP , Overton Jerry , Yap Susan , Andresen Derek , Yong David KL , Lim Swee Han , Anantharaman V
Published: October 2022

Introduction: Pre-hospital ambulance calls are not random events, but occur in patterns and trends that are related to movement patterns of people, as well as the geographical epidemiology of the population. This study describes the geographic-time epidemiology of ambulance calls in a large urban city and conducts a time demand analysis. This will facilitate a Systems Status Plan for the deployment of ambulances based on the most cost-effective deployment strategy.

Materials and Methods: An observational prospective study looking at the geographic-time epidemiology of all ambulance calls in Singapore. Locations of ambulance calls were spot-mapped using Geographic Information Systems (GIS) technology. Ambulance response times were mapped and a demand analysis conducted by postal districts.

Results: Between 1 January 2006 and 31 May 2006, 31,896 patients were enrolled into the study. Mean age of patients was 51.6 years (S.D. 23.0) with 60.0% male. Race distribution was 62.5% Chinese, 19.4% Malay, 12.9% Indian and 5.2% others. Trauma consisted 31.2% of calls and medical 68.8%. 9.7% of cases were priority 1 (most severe) and 70.1% priority 2 (moderate severity). Mean call receipt to arrival at scene was 8.0 min (S.D. 4.8). Call volumes in the day were almost twice those at night, with the most calls on Mondays. We found a definite geographical distribution pattern with heavier call volumes in the suburban town centres in the Eastern and Southern part of the country. We characterised the top 35 districts with the highest call volumes by time periods, which will form the basis for ambulance deployment plans.

Conclusion: We found a definite geographical distribution pattern of ambulance calls. This study demonstrates the utility of GIS with despatch demand analysis and has implications for maximising the effectiveness of ambulance deployment.

Keywords: Demand analysis, Despatch, Emergency Medical Services
Functional Outcome Study of Mega-Endoprosthetic Reconstruction in Limbs With Bone Tumour Surgery
Authors: Tan Peh Khee , Tan Mann Hong
Published: October 2022

Introduction: Amputation is no longer the sole contribution of the orthopaedic surgeon to the management of primary bone tumours. Improvements in the design of endoprostheses and surgical reconstructive techniques have combined with advances in chemotherapeutic regimens to result in surgical procedures for salvaging limbs with aggressive sarcomas and in limb reconstruction. This has made limb salvage a viable alternative to amputation in many cases. The aim of this study was to evaluate functional outcome and complications of patients with primary bone tumours who were treated with re-section and mega-endoprosthetic replacement.

Materials and Methods: Nineteen patients with bone tumours were retrospectively reviewed. These patients had wide local re-section and mega-endoprosthetic reconstruction performed between 1999 and 2006 in a tertiary hospital. Functional evaluation was performed based on the Musculoskeletal Tumour Society (MSTS) scoring system, with numerical values from 0 to 5 points assigned for each of the following 6 categories: pain, function, emotional acceptance, use of supports, walking ability and gait. These values were added, and the functional score was presented as a percentage of the maximum possible score. Complications were also analysed.

Results: The final mean functional score was 78.3% ± 16.6%. Eight patients had complications related to surgery, including infection and subluxation of hip implant. Six patients had infection, while 2 had subluxation of hip implants. Infection was a common complication in our study. None had implant breakage, loosening or fracture. We found no statistical difference in the functional outcome between upper limb and lower limb procedures, and between hip and knee procedures. T-test also showed no evidence of gender differences in functional outcome. Kaplan-Meier survival analysis revealed the mean survival duration of megaprosthesis to be 75.6 months.

Conclusion: Mega-endoprosthetic reconstruction in limb salvage provides good functional outcome in patients with bone tumours. The early results from patients treated with mega- endoprosthesis have been encouraging.

Keywords: Limb salvage, Megaprosthesis
Intramuscular Gentamicin Improves the Efficacy of Ciprofloxacin as an Antibiotic Prophylaxis for Transrectal Prostate Biopsy
Authors: Ho Henry SS , Ng Lay Guat , Tan Yeh Hong , Yeo Mavis , Cheng Christopher WS
Published: October 2022

Introduction: Infection-related complications after transrectal ultrasound guided prostatic biopsy (TRPB) could be life threatening. Our centre observed sepsis after TRPB despite prophylactic oral ciprofloxacin. We reviewed all cases of post-TRPB sepsis with their bacteriology and evaluated if the addition of intramuscular (I/M) gentamicin to standard prophylaxis before TRPB could reduce its incidence.

Materials and Methods: In a single urological centre, we performed an interventional study that compared a prospective group with retrospective control. The latter is known as the “cipro-only” group included consecutive patients who underwent TRPB between 1 September 2003 and 31 August 2004. The addition of I/M gentamicin 80mg half an hour before TRPB started on 1 September 2004. All subsequent patients who underwent TRPB until 31 August 2005 were included in the “cipro+genta” group. Patients who did not receive the studied antibiotics were excluded.

Results: There were 374 patients in the “cipro+genta” group and 367 patients in the “cipro-only” group with comparable profiles. There were 12 cases of post-TRPB sepsis in the “cipro-only” group and 5 cases in the “cipro+genta” group. Ciprofloxacin-resistant Escherichia coli (E. coli) was the only pathogen isolated in both groups. In the “cipro-only” group, 9 patients had positive blood cultures and 8 were sensitive to gentamicin. In the “cipro+genta” group, the only positive E. coli was gentamicin-resistant. One patient in the “cipro+genta” group was admitted to the intensive care unit with septicaemia.

Conclusion: The addition of I/M gentamicin to oral ciprofloxacin is a safe and effective prophylactic antibiotic regime in reducing the incidence of post-TRPB sepsis.

Key words: Antibiotics, Infection, Prophylaxis, Prostate Biopsy