bluuebunny/crossref_metadata_2025 huggingface dataset:
A Redesigned Order Entry System for Reducing Low-Value Preprocedural Cardiology Consultations: Quality-Improvement Cohort Study
Authors: Winchester David E , Cagino Leigh
Published: May 2020

Background

Preprocedural cardiac evaluation is a common reason for outpatient cardiology visits. Many patients who are referred to cardiology clinics for preprocedural evaluation are at low risk of perioperative events and do not require any further management. Our facility treats patients over a large geographic area; avoiding low-value consultations reduces time and travel burdens for patients.

Objective

Our study objective was to assess the impact of a novel algorithm in the electronic order entry system aimed to guide clinicians toward patients who may benefit from cardiovascular referral.

Methods

We retrospectively reviewed in-person consultations and electronic consultations (e-consults) to our cardiology service before and after implementation of the novel algorithm to assess changes in patterns of care. Data were stored in a custom electronic database on internal servers.

Results

We reviewed 603 consultations to our cardiology clinic and found that 89 (14.7%) were sent for preprocedural evaluation. Of these, 39 (43.8% of preprocedural consultations) were e-consults. After implementation, we reviewed 360 consultations. The proportion of consultations for preprocedural evaluation did not decrease (n=47, 13.0%; P=.39). We observed an absolute increase of 13.6% in the proportion of consultations ordered as e-consults (27/47, 57.4%). During the postintervention period, we received no remarks, concerns, or criticisms from ordering clinicians about the process change and no reports of adverse events.

Conclusions

Implementation of an ordering algorithm to reduce low-value preprocedural cardiology evaluations did not lead to a reduction in the number of overall preprocedural cardiology consultations. The number of patients seen electronically increased, potentially improving clinic access and reducing travel burden for patients.
Exploring the Health-Related Quality of Life of Patients Treated With Immune Checkpoint Inhibitors: Social Media Study (Preprint)
Authors: Cotté François-Emery , Voillot Paméla , Bennett Bryan , Falissard Bruno , Tzourio Christophe , Foulquié Pierre , Gaudin Anne-Françoise , Lemasson Hervé , Grumberg Valentine , McDonald Laura , Faviez Carole , Schück Stéphane
Published: May 2020

BACKGROUND

Immune checkpoint inhibitors (ICIs) are increasingly used to treat several types of tumors. Impact of this emerging therapy on patients’ health-related quality of life (HRQoL) is usually collected in clinical trials through standard questionnaires. However, this might not fully reflect HRQoL of patients under real-world conditions. In parallel, users’ narratives from social media represent a potential new source of research concerning HRQoL.

OBJECTIVE

The aim of this study is to assess and compare coverage of ICI-treated patients’ HRQoL domains and subdomains in standard questionnaires from clinical trials and in real-world setting from social media posts.

METHODS

A retrospective study was carried out by collecting social media posts in French language written by internet users mentioning their experiences with ICIs between January 2011 and August 2018. Automatic and manual extractions were implemented to create a corpus where domains and subdomains of HRQoL were classified. These annotations were compared with domains covered by 2 standard HRQoL questionnaires, the EORTC QLQ-C30 and the FACT-G.

RESULTS

We identified 150 users who described their own experience with ICI (89/150, 59.3%) or that of their relative (61/150, 40.7%), with 137 users (91.3%) reporting at least one HRQoL domain in their social media posts. A total of 8 domains and 42 subdomains of HRQoL were identified: Global health (1 subdomain; 115 patients), Symptoms (13; 76), Emotional state (10; 49), Role (7; 22), Physical activity (4; 13), Professional situation (3; 9), Cognitive state (2; 2), and Social state (2; 2). The QLQ-C30 showed a wider global coverage of social media HRQoL subdomains than the FACT-G, 45% (19/42) and 29% (12/42), respectively. For both QLQ-C30 and FACT-G questionnaires, coverage rates were particularly suboptimal for Symptoms (68/123, 55.3% and 72/123, 58.5%, respectively), Emotional state (7/49, 14% and 24/49, 49%, respectively), and Role (17/22, 77% and 15/22, 68%, respectively).

CONCLUSIONS

Many patients with cancer are using social media to share their experiences with immunotherapy. Collecting and analyzing their spontaneous narratives are helpful to capture and understand their HRQoL in real-world setting. New measures of HRQoL are needed to provide more in-depth evaluation of Symptoms, Emotional state, and Role among patients with cancer treated with immunotherapy.
A Review on Signal in Pharmacovigilance
Authors: Rani Ritu , Chand Subhash , Singh Arjun , Kumar Deovrat , Devi Meena
Published: May 2020

A safety signal is data or information that may suggest a new causal association, or contribute new information about a known association, between a medicine and an adverse event that justifies further investigation. Signals are generated from several sources such as spontaneous reports, clinical studies and the scientific literature. Signal is a potential medicine safety issues, which are derived from individual case safety reports in vigiBase. Signal detection is a cornerstone of drug development process ensuring drug safety. The early detection of Signals helps to improve patient safety and reduce economic burden due to escalating cost of medications and unwanted adverse effects associated with it. The present study is an initiative to make significant contribution towards health-care system by generating evidence based data to benefit health care professionals, consumers, pharmaceutical companies and regulatory authorities.Signal detection and signal strengthening is the most important aspect in Pharmacovigilance which plays an important role in ensuring that patients receive safe drugs. For detection of adverse drug reactions, clinical trials usually provide limited information as they are conducted under strictly controlled conditions. Some of the adverse drug reaction can be detected only after long term use in larger population and in specific patient groups due to specific concomitant medications or disease.
Assessment of In-Vivo Antioxidant Potential of Hydro-Alcoholic Extract and Ethyl Acetate Fraction of Aerva Javanica Linn. Flowering Tops
Authors: Khunteta Alok , Swarnkar Surendra K , Gupta Manish Kumar , Swarnkar Aruna , Sharma Swapnil , Paliwal Sarvesh
Published: May 2020

Aerva javanica (Amaranthaceae) is a grey coloured woolly perennial tomentose shrub. Its traditional and folklore usage motivates further investigation on its pharmacognostic parameters and pharmacological potential. Hydro-alcoholic extract (AJCE) was prepared from flowering tops of A. javanica. In order to work further on activity guided fractions, ethyl acetate (AJEAF) fraction was prepared.  Therefore, in order to establish its antioxidant potential, in-vivo effect on LPO, GSH, SOD and catalase activity was determined. For comparison, silymarin and Centella asiatica extract (CAE) were used as standard antioxidant compound/extract. Lipid peroxidation in term of MDA content expressed as nM/mg, which was 82.18 and 67.39 for AJCE with increasing doses of complete hydro-alcoholic extract (AJCE represented as AJCE-1 and AJCE-2) and 51.65 for AJEAF in contrast to 40.64 nM/mg for standard silymarin and 46.81 nM/mg for standard CAE. GSH content was determined as 3.12, 3.82 and 4.56 μg/mg wet tissue in contrast to 5.59 for standard silymarin and 4.42 for standard CAE. Superoxide scavenging was expressed as SOD U/mg wet tissue, determined as 7.26, 9.16 and 9.91 U/mg wet tissue for AJCE-1 (250 mg/kg i.p. b.w), AJCE-2 (500 mg/kg i.p. b.w), and AJEAF respectively in comparison to silymarin (10.11) and CAE (46.81 U/mg wet tissue). Catalase activity expressed as μM of H2O2 decomposed / min / mg wet tissue was determined as 0.61, 0.72 and 0.78 repectively for AJCE-1 (250 mg/kg i.p. b.w), AJCE-2 (500 mg/kg i.p. b.w), and AJEAF. Results indicated the SOD values and total antioxidant power of DEE and EAF fractions even better than standard ascorbic acid which expressed the prospective potential of fractions (DEE and EAF) against metabolic disorders.
Anti-Inflammatory Potential of Some Essential Oils: A Review
Authors: Kushwah Ritika , Gupta M K
Published: May 2020

Inflammation and pain are common phenomena associated with a number of diseases. Inflammatory diseases result from the body’s response to tissue damage, and if the resolution is not adequate or the stimulus persists, there will be progression from acute inflammation to chronic inflammation, leading to the development of cancer and neurodegenerative and autoimmune diseases.  It is necessary to search for new biologically active compounds with anti-inflammatory activity. Essential oils are complex mixtures isolated from aromatic plants which may possess antioxidant and anti-inflammatory activities. This article briefly summarizes the potential of essential oils and their compounds for the treatment of inflammatory diseases.
Assessment of Drug Related Problems among Type 2 Diabetes Mellitus Patients with Hypertension in Doloksanggul Hospital, North Sumatera: A Retro prospective Study
Authors: Purba Eva Dewi , M Khairunnisa , Anjelisa Hasibuan Poppy
Published: May 2020

Objective: The aim of this study was to assess the drug-related problems (DRPs) in Type 2 diabetes mellitus(T2DM) patients whom also diagnosed with hypertension. Methods: The retrospective study was conducted from October to December 2018 at Doloksanggul Hospital in North Sumatera, Indonesia involving 42 T2DM with hypertension patients according to research inclusion criteria. The assessment of DRPs was based on the Pharmaceutical Care Network Europe (PCNE) tools version 8.01. Results: This study identified 41 DRPs, averaging 0.98±0.24 DRPs per patient. The majority of problems were treatment effectiveness problems 97.62% (41 patients) while the patient related was the main causes (47.24%). The most intervention was conducted at patient level (71.62%).Conclusion: Early detection of DRPs by pharmacist are essential to prevent DRPs and to ensure the effectiveness of drug therapy.
Evaluation of Drug Management For Tuberculosis (TB) Program At Pharmaceutical Installation Public Health Department of North Sumatra Province
Authors: Sabri April , S Wiryanto M , M Khairunnisa
Published: May 2020

Objective: Drug management consists of planning, storing and distribution. It is one of the important duty of Public Health Department of North Sumatra Province. Poor drug management will give a negative impact on service quality. This research aimed to evaluate the management of drug programs for tuberculosis (TB) in 2017, 2018 and 2019 in the Public Health Department of North Sumatra Province. The research was conducted in July - September 2019.

Method: This research was descriptive with quantitative data obtained retrospectively and concurrently. Qualitative data were obtained through observations and interviews with informants. The data obtained were analyzed using indicators and compared with the results of the research.

Result: The result of the research showed that planning, storing and distributing drug for the TB program in the Public Health Department of North Sumatra Province had not fully met the indicator standards. This was indicated by the 6 indicators which had not met the standard, that were the accuracy of planning; planning deviations; level of drug supply; percentage of expired drug; Inventory Turn Over Ratio (ITOR); the average time of drug vacancies and the percentage of dead drug stock and 3 indicators had met the standards, which were the percentage of expired drugs, the structuring system of drugs and the matching of the number of real goods with stock.

Conclusion: the conclusion of this research is drug planning of Public Health Department of North Sumatra Province uses consumption method of previous period. Storage of drugs uses the FIFO/FEFO system. Drug distribution in the North Sumatra Provincial Health Office is based on requests from the District/City.
The Potency of Artocarpus Heterophyllus Leaf as a Facial Skin Care Ingredient in Clay Mask Formulation
Authors: Widyawati Tri , Syarifah Siti , Daulay Milahayati , Lolyta Fitri Mustanti
Published: May 2020

Artocarpus heterophyllus (Ah), common name as nangka,  has been reported to have antidiabetic, antihyperlipidemia, antimicrobial and antioxidant activity. Balinese women used its leaves for facial treatment. This study aims to evaluate its leaf potency for facial skin care. Ethanol extract of Ah (EEAh) that obtained by maceration was prepared into 3 clay mask formulations (FI: 1%, FII:3% and FIII:5%). F0 was used as control group. A total of 12 volunteers were treated with clay mask to evaluate its effect on moisture and pores size after intervention. The data were analysed using Kruskall Wallis and Mann Whitney test. The results showed that skin moisture increased after intervention (FI:3.7%; FII:4.7%;FIII:7.3%). Pores size decreased in FI (6.3%) and FII (13.4%). Statistically, there were significant different between F0-F1 (p=0.043), F0-F2 and F0-F3 (p=0.046 of each). The present study conclude that clay mask containing A. heterophyllus leaf ethanol extract have potency to be used as facial skin care.
Estimativa do aproveitamento energético de resíduos sólidos urbanos com o auxílio de processos biológicos
Authors: Drudi Ricardo , Martins Gilberto , Toneli Juliana Tófano de Campos Leite , Antonio Graziella Colato , Drudi Kelly Cristina Rosa
Published: May 2020

O crescente número de resíduos sólidos urbanos nas cidades, estão resultando em grandes problemas para as administrações públicas. Atualmente cerca de 58% dos resíduos coletados no Brasil são enviados para aterros sanitários, e 42% são destinados a locais inadequados. O problema não está relacionado somente com área apropriada para o depósito desses resíduos, mas com a produção natural de metano, gás muito mais prejudicial ao meio ambiente do que o próprio dióxido de carbono, porém com alto poder calorífico. Este trabalho buscou construir, através de métodos de análise estatística, um modelo que possibilite prever a produção de biogás em um aterro sanitário. Foram realizadas simulações, utilizando-se de parâmetros da literatura, que possuem características de distribuições gaussianas. De acordo com as simulações, foi possível projetar um modelo hipotético que leva em consideração as variabilidades que ocorrem com os resíduos depositado em um aterro sanitário.
Avaliação Institucional: O Modelo Brasileiro e Seu Potencial de Mensuração das Metodologias Ativas
Authors: Costa Neto Arlindo Menezes da , Moura Angélica Maria Constantino de , Oliveira Edna Maria da Silva medeiros de , Araújo Aneide Oliveira de
Published: May 2020

O presente trabalho se propôs a elaborar uma revisão bibliográfica sobre como o modelo brasileiro de avaliação institucional consegue lidar com as metodologias ativas, para tal, foi comparado aos modelos norte-americano e europeu de avaliação institucional, expondo os pontos similares entre eles e suas divergências. Partindo da formação, também foi observado como se dá a avaliação do profissional contábil, através das certificações que permitem o exercício da profissão do contador(a), buscando em tal observação reconhecer se as metodologias ativas poderiam refletir habilidades desejadas pelos participantes do mercado, podendo, portanto, servir como um indicador positivo para seu uso, enquanto que ao se observar como se dá o credenciamento também nos tornamos capazes de observar se os métodos avaliativos conseguem servir como indicadores das habilidades e competências resultantes das ações e métodos empregados pelas IES. Quanto à avaliação institucional, observa-se que o modelo brasileiro acaba por compartilhar similaridades com o modelo europeu e norte-americano. Já quanto ao credenciamento do profissional contábil, o modelo brasileiro, quando comparado ao norte-americano apresenta uma menor aderência às avaliações das habilidades desenvolvidas através do uso de metodologias ativas, o que acaba por gerar questões sobre as expectativas do mercado sobre o profissional contábil.
Sanciones penales más recurrentes de los contadores públicos en Colombia: un desafío para la ética profesional
Authors: Rubio-Rodríguez Gustavo Adolfo , Susunaga Rodríguez José Alfredo , Solano De La Oz Julio León , Guzmán García Leidy Milena , Gordo Vargas María Angélica
Published: May 2020

Este manuscrito tiene la intención de profundizar la responsabilidad que el Contador Público adquiere frente a su trabajo, que está inmerso en el cumplimiento de normas, principios legales y técnicas aplicables, que deben cumplir para garantizar que el trabajo se cumpla. Por esta razón, en el gremio de Contadores Públicos desde su graduación de la academia, surge la necesidad de abogar por la importancia de la ética profesional, ya que existe una falta de compromiso con la profesión de esta profesión. El objetivo que guía la presente investigación es analizar las causas contempladas en el Capítulo IV de la Ley 43 de 1990 - Código de Ética Profesional - a partir de los casos penalizados de los profesionales de la profesión que fueron sancionados por la Junta Central de Contadores durante el período que abarca 2014-2016, en Colombia. Se tomará como base para la construcción metodológica, la información proporcionada por la Junta Central de Contadores, ya que se espera que construya la matriz que guiará el desarrollo metodológico mixto de la investigación, donde se pueden contemplar todos los principios éticos vulnerables de los contadores. público, y por falta de conocimiento, omisión, dudas en el desarrollo adecuado de las profesiones o las presiones externas. A lo largo de la investigación se evidenciaron las debilidades en lo que se refiere a los deberes que el Contador Público debe asumir. la información proporcionada por la Junta Central de Contadores, ya que se espera que construya la matriz que guiará el desarrollo metodológico mixto de la investigación, donde se pueden contemplar todos los principios éticos vulnerables de los contadores públicos, incluida la falta de conciencia, la omisión, dudas sobre el correcto desarrollo de la profesión o las presiones externas. A lo largo de la investigación se evidenciaron las debilidades en lo que se refiere a los deberes que el Contador Público debe asumir. la información proporcionada por la Junta Central de Contadores, ya que se espera que construya la matriz que guiará el desarrollo metodológico mixto de la investigación, donde se pueden contemplar todos los principios éticos vulnerables de los contadores públicos, incluida la falta de conciencia, la omisión, dudas sobre el correcto desarrollo de la profesión o las presiones externas. A lo largo de la investigación se evidenciaron las debilidades en lo que se refiere a los deberes que el Contador Público debe asumir.
O CONCEITO DE ENERGIA EM PERIÓDICOS DA ÁREA DE EDUCAÇÃO EM CIÊNCIAS: A DISCUSSÃO DA CONSERVAÇÃO/DEGRADAÇÃO DE ENERGIA EM PRÁTICAS EDUCATIVAS DE PERSPECTIVAS FREIRE-CTS
Authors: Hansen Taís Regina , Marsango Daniel , Brum Débora Larissa , Clerici Kátia Slodkowski , Santos Rosemar Ayres dos
Published: May 2020

O conceito de energia é amplamente utilizado no cotidiano para descrever e explicar vários fenômenos presentes na natureza. Desse modo, permite abordagem interdisciplinar e unificadora para o currículo escolar, levando à compreensão de várias relações da nossa sociedade com o ambiente, nas quais muitas mudanças do ecossistema envolvem as transformações de energia em processos biológicos, físicos e químicos. Por exemplo, os processos de transformação de energia estão presentes em praticamente todas as máquinas construídas pela sociedade e, por vezes, constitui o pano de fundo de muitos problemas socioambientais como as mudanças climáticas. Assim, para a compreensão e enfrentamento desses, considera-se fundamental o entendimento do conceito de Energia. Nesse sentido, investigamos: como o tema energia (conservação/degradação) tem sido trabalhado no currículo da Educação Básica? Objetivando, por meio de pesquisa bibliográfica, compreender quais têm sido os encaminhamentos, no campo curricular, dados a esse conceito. Metodologicamente seguimos a Análise de Conteúdo, fundamentada em Bardin, sendo o corpus composto por seis periódicos considerando sua representatividade, conforme Educação em Ciências. Os resultados são discutidos a partir de cinco categorias a priori, obtidas de Auler, Dalmolin e Fenalti (2009): Abrangência dos temas; Surgimento dos temas; Disciplinas envolvidas na estruturação dos temas; Relação tema/conteúdo; Conteúdo tradicional designado de tema. Por meio das quais, verificamos a importância da abordagem temática freireana e CTS para o entendimento do conceito de Energia em suas diversas áreas do saber do currículo escolar. Assim, por meio da investigação compreendemos que o conceito de energia diferencia-se em diferentes áreas; entretanto, nas práticas efetivas em que ele foi trabalhado, houve dificuldades dos professores na abordagem do conceito, bem como no reconhecimento da energia como sendo estruturadora para os componentes curriculares que ministram. Desse modo, em parcela das abordagens o mesmo continuou muito ligado às concepções tradicionais. Entretanto, constatamos que a maioria das práticas foram capazes de propiciar mais participação dos estudantes no processo educacional. Também, o conceito pode ser considerado como chave para abordagem de temas universais e da promoção da interdisciplinaridade na Educação Básica, rompendo a visão de estar restrito a um conteúdo de determinado componente curricular. Desta forma, a temática pode possibilitar a ampliação de trabalhos e aplicações na área da educação formal, que levem em conta o caráter de formação social e cidadã, de sujeitos crítico-reflexivos e participativos, aptos a intervirem e apontarem solução de problemas de sua comunidade, de seu mundo vivido.
MODELO DE RECONSTRUÇÃO EDUCACIONAL COMO UM APORTE TEÓRICO E METODOLÓGICO PARA O DESIGN DE AMBIENTES DE ENSINO E APRENDIZAGEM DA CIÊNCIA
Authors: Silva Michelle Garcia da , Ferreira Helaine Sivini
Published: May 2020

Neste artigo o Modelo de Reconstrução Educacional (MRE) foi apresentado como um aporte teórico e metodológico para o design de ambientes de ensino e aprendizagem da ciência. Para isso, foi necessário elucidar o entendimento sobre as grandes teorias, os quadros intermediários e as ferramentas de design no processo de design de intervenções educacionais. A partir deste entendimento foi feito o aprofundamento teórico do MRE, que resultou na clarificação do seu quadro intermediário. Além disso, o aprofundamento da discussão metodológica do MRE permitiu um entendimento mais claro das relações entre seus três componentes: análise da estrutura do conteúdo, investigações sobre as perspectivas dos estudantes e design e avaliação de ambientes de ensino e aprendizagem. Todas essas discussões contribuíram para que o MRE fosse defendido neste trabalho como um modelo teórico e metodológico frutífero para auxiliar professores e pesquisadores do ensino de ciências no processo de design de intervenções educacionais que tratem de conteúdos científicos.
USO DE ANIMAIS NO ENSINO: UM ESTUDO DE CASO EM CURSOS DE CIÊNCIAS BIOLÓGICAS
Authors: Costa Desirrèe Farias , Valle Mariana Guelero do
Published: May 2020

Este artigo teve como objetivo investigar o uso de animais no ensino em Cursos de Ciências Biológicas de uma Instituição de Ensino Superior (IES). Utilizou-se abordagem qualitativa de pesquisa e tipologia de estudo de caso. Foram analisados os Projetos Pedagógicos dos Cursos (PPC), os programas das disciplinas e a percepção de docentes e discentes. Verificou-se que o registro do uso de animais no ensino ainda é pouco contemplado nos documentos relacionados aos Cursos de Ciências Biológicas da instituição. Faz-se necessário que os documentos detalhem com maior clareza as metodologias a serem utilizadas, suas finalidades e os recursos didáticos que serão efetivamente empregados, em consonância com as diretrizes previstas pelo Conselho Nacional de Controle e Experimentação Animal (CONCEA). Em relação à percepção de docentes e discentes, identificou-se que parte caracteriza essa prática como sendo imprescindível para o aprendizado do conteúdo biológico teórico, enquanto outros defendem o uso de recursos alternativos.É importante que, no contexto do ensino, o uso de animais seja ponderado, especialmente levando-se em conta sua real necessidade para atingir os objetivos didáticos, os impactos que esse uso pode causar, bem como a questão da valorização e do respeito à vida.
Central KATP channels modulate glucose effectiveness in humans and rodents
Authors: Admin Ada , Carey Michelle , Lontchi-Yimagou Eric , Mitchell William , Reda Sarah , Zhang Kehao , Kehlenbrink Sylvia , Koppaka Sudha , Maginley Sylvan Roger , Aleksic Sandra , Bhansali Shobhit , Huffman Derek M. , Hawkins Meredith
Published: May 2020

Hyperglycemia
is a potent regulator of endogenous glucose production (EGP). Loss of this
‘glucose effectiveness’ is a major contributor to elevated plasma glucose
concentrations in type 2 diabetes (T2D). ATP-sensitive potassium channels (KATP
channels) in the central nervous system (CNS) have been shown to regulate EGP
in humans and rodents. We examined the contribution of central KATP
channels to glucose effectiveness. Under fixed hormonal conditions (‘pancreatic
clamp’ studies), hyperglycemia suppressed EGP by ~50% in both non-diabetic
humans and normal Sprague Dawley rats. By contrast, antagonism of KATP
channels with glyburide significantly reduced the EGP-lowering effect of
hyperglycemia in both humans and rats. Furthermore, the effects of glyburide on
EGP and gluconeogenic enzymes in rats were abolished by intracerebroventricular
(ICV) administration of the KATP channel agonist diazoxide. These findings
indicate that about half of EGP suppression by hyperglycemia is mediated by
central KATP channels. These central mechanisms may offer a novel
therapeutic target for improving glycemic control in T2D.
O DESENVOLVIMENTO DO PENSAMENTO CRÍTICO SOBRE EDUCAÇÃO AMBIENTAL E MEIO AMBIENTE: CONCEPÇÃO DOS ALUNOS DO ENSINO MÉDIO DO MUNICÍPIO DE UNIFLOR - PR
Authors: Fernandes Guimarães Severo dos Santos Bianca , Regina Royer Marcia
Published: May 2020

Discussões a respeito de questões ambientais têm conquistado espaço na sociedade e a escola como uma das principais instituições de socialização do ser humano possui um papel fundamental no desenvolvimento de uma Educação Ambiental emancipatória, capacitando o indivíduo para viver harmonicamente com o Meio Ambiente. O objetivo da pesquisa foi analisar a concepção dos alunos do Ensino Médio de uma instituição pública do município de Uniflor sobre Educação Ambiental, além de buscar compreender a percepção sobre Meio Ambiente como participantes das ações humanas na natureza. Os dados foram coletados por meio de questionários e os resultados indicaram uma concepção totalmente conservacionista de Meio Ambiente. Logo, os professores desses alunos, ao planejarem atividades em Educação Ambiental, devem considerar esses resultados a fim de construir, coletivamente com toda a comunidade escolar, um conceito de Meio Ambiente mais amplo e crítico.
RANCANG BANGUN KULKAS MINI PORTABLE MENGGUNAKAN PELTIER
Authors: Suryadi Aris , Firmansyah Achmad
Published: May 2020

Pendinginan dengan peltier thermo electric cooler menggunakan modul TEC-12706 untuk mengetahui temperatur yang dicapai pada media dan memberikan inovasi baru dari modul peltier guna mengurangi komponen pada pendinginan konvensial pada umumnya. Dengan memanfaatkan proses kalor pada saat modul peltier dilewati arus maka alat ini akan memindahkan panas dari satu sisi ke sisi lain, biasanya menghasilkan perbedaan panas sekitar 30°C. Pengujian dilakukan tiga kali, untuk volume air yang berbeda dalam 20 menit pada setiap pengujian hasil data yang diperoleh bahwa pada penurunan temperatur, untuk pengujian pertama dengan volume 100 mL air yaitu 1,6°C dan 3°C pada 200 mL air dan dengan persentase penurunan suhu mencapai 5,07% pada 100 mL air dan 9,43% volume 200 mL air, pada pengujian kedua dengan volume 100 mL air yaitu 3,5°C dan 3,6°C pada 200 mL air dan dengan persentase penurunan suhu mencapai 10,67% pada 100 mL air dan 11,28% volume 200 mL air, pada pengujian ketiga dengan volume 100 mL air yaitu 1,8°C dan 1,9°C pada 200 mL air dan dengan persentase penurunan suhu mencapai 5,84% pada 100 mL air dan 6,10% pada 200 mL air.
DESAIN CETAKAN PLASTIK MULTI CAVITY DENGAN SISTEM INTERCANGEABLE MOLD INSERT
Authors: Hakim Rahman , Pratama Putra Vicqi , Maskarai Abulija , Priyanto Hasan
Published: May 2020

Berdasarkan data dari Survey Industri BP Batam tahun 2017, peningkatan kapasitas produksi produk plastik semakin signifikan. Hal ini ditunjukkan dengan banyaknya perusahaan dari China yang datang ke Batam untuk mengembangkan usaha plastik mereka. PT. Schneider Electric Batam, salah satunya yang mengalami peningkatan kapasitas produksi. Return pin merupakan salah satu produk yang akan dikembangkan, melalui penambahan jumlah core dan cavity nya. Jenis bahan baku plastik yang digunakan, yaitu POM (Polyoxymethylene), serta Stavax ESR sebagai bahan baku mold insert yang digunakan. Penelitian ini bertujuan untuk peningkatan kapasitas produksi cetakan plastik, dengan usulan perancangan baru untuk merubah mold insert dan tetap mempertahankan mold based yang telah ada. Perancangan dilakukan dengan metode VDI (Verein Deutsche Inginieuer) 2222 yang merupakan standar perancangan dalam membuat desain Mold. Software CAD yang digunakan adalah Siemens NX 9.0 dan Software CAE yang digunakan adalah Moldex 3D Flow Mold. Dari perancangan ini, didapatkan hasil cycle-time sebesar 11.5 detik dengan penghematan anggaran sebesar 46.7%.
PROTOTIPE PENGAWAS SISTEM PROTEKSI ARUS LEBIH ELEKTRONIK SECARA NIRKABEL
Authors: Anwar Arif Rahmadi , Siswanto Diky
Published: May 2020

Relay arus lebih adalah peralatan yang sangat penting dalam sistem kelistrikan. Alat ini digunakan sebagai proteksi dari anomali atau gangguan yang dapat menimbulkan lonjakan arus dalam waktu singkat seperti ketika terjadi hubung singkat. Besarnya arus dapat merusak peralatan karena melebihi kemampuan hantar arus dari peralatan tersebut. Oleh sebab itu sistem proteksi menjadi peralatan yang wajib digunakan dalam sistem kelistrikan. Sistem proteksi ini terdiri dari beberapa peralatan  seperti relay arus lebih, catu daya, baterai dan circuit breaker. Peralatan tersebut dirangkai menjadi satu sistem dengan menggunakan kabel yang rawan kendur, terlepas dan lain sebagainya yang masih belum terpantau kesiapannya setiap saat sehingga dapat berpotensi menyebabkan kegagalan sistem proteksi. Arduino uno merupakan perangkat mikrokontroler yang memiliki desain open source sehingga dapat diaplikasikan di semua peralatan elektronik. Alat ini dapat diterapkan dalam sistem proteksi untuk memantau tegangan catu daya dan baterai dengan menggunakan port analog input serta mengawasi rangkaian kabel trip coil dengan komponen optocoupler PC017 sebagai sensor input digital pada Arduino. Data yang diterima oleh Arduino uno akan dikirimkan ke online database dengan menggunakan wifi shield ESP8266, kemudian data tersebut akan ditampilkan pada aplikasi dalam ponsel Android. Dengan demikian, jika terdapat kerusakan pada salah satu peralatan tersebut maka petugas dapat segera melakukan perbaikan sebelum terjadi kegagalan sistem proteksi.
PENENTUAN PENYAKIT PARU DENGAN MENGGUNAKAN JARINGAN SARAF TIRUAN
Authors: Listyalina Latifah , Utari Evrita Lusiana , Puspaningtyas Desty Ervira
Published: May 2020

Organisasi Kesehatan Dunia (WHO) dan Organisasi Penanggulangan Kanker Dunia (UICC) memprediksikan terjadinya peningkatan kejadian kanker sebesar 300% pada tahun 2030. Salah satu jenis kanker ialah kanker paru. Deteksi kanker paru dapat dilakukan menggunakan rontgen. Diagnosis kanker paru dapat dilakukan melalui pengamatan hasil dari citra foto rontgen secara teliti. Otomasi dari hasil citra X-Ray dapat digunakan oleh praktisi kesehatan dalam pendeteksian kanker paru. Perancangan perangkat lunak jaringan saraf tiruan dari citra foto rontgen dilakukan melalui beberapa langkah yaitu pengolahan citra, seperti median filter, ekualisasi histogram adaptif, dan transformasi kosinus diskrit sebagai ekstraksi fitur citra yang selanjutnya dijadikan masukan jaringan saraf tiruan serta dengan didahului oleh proses pra pengolahan citra. Tingkat akurasi pendeteksian kanker paru melalui citra foto rontgen paru sebesar 72,97%.
KENDALI ROBOT LENGAN 4 DOF BERBASIS ARDUINO UNO DAN SENSOR MPU-6050
Authors: Utomo Bagus , Dwi Setyaningsih Noor Yulita , Iqbal Mohammad
Published: May 2020

Dimasa sekarang ini robot banyak digunakan dalam berbagai bidang kehidupan, terdapat berbagai jenis robot yang dikembangkan salah satunya adalah robot lengan karena memiliki fungsi yang sama dengan lengan manusia. Salah satu kendala dalam pengoperasian robot adalah karena kebanyakan robot memerlukan pemrograman terlebih dahulu untuk mengoperasikan sehingga sulit bagi orang awam. Tujuan dari penelitian ini adalah membuat sistem kendali lengan robot yang dapat mengendalikan lengan robot hanya dengan menggerakan tangan dan menekan tombol. Penelitian ini menggunakan sensor MPU-6050 sebagai sensor sudut dan potensiometer sebagai pengatur gerakan robot, selain itu juga menggunakan Arduino Uno sebagai pengolah masukan sensor agar dapat mengendalikan lengan robot. Adapun robot yang digunakan adalah robot lengan 4 DOF (Degree Of Freedom) dengan penggerak motor servo. Penelitian ini menggunakan metode research and development yaitu dengan mempelajari dan mengembangkan penelitian sebelumnya. Pengujian sensor MPU-6050 mendapatkan hasil dengan nilai error pembacaan sebesar 0,72% pada sumbu X dan 0,68% pada sumbu Y. Waktu yang dibutuhkan untuk sekali proses pemindahan barang adalah selama 3 detik. Hasil dari sistem yang telah dibuat, robot mampu memindahkan barang ketempat yang diinginkan. Tingkat keberhasilan proses pindah barang menggunakan robot lengan 4 DOF adalah 100%.
PENERAPAN MODEL DELONE DAN MCLEAN PADA SI-PMB ONLINE DARI PERSPEKTIF PENGGUNA UNTUK MENINGKATKAN KUALITAS LAYANAN
Authors: Suradi Agustinus , Windarti Mariana Windarti
Published: May 2020

Inovasi strategi pengembangan sistem informasi perlu dikembangkan untuk mendukung kesuksesan dan kualitas layanan sistem penerimaan mahasiswa baru. Masyarakat pengguna sistem informasi penerimaan mahasiswa baru sering mengalami kesulitan ketika mencari informasi yang mereka butuhkan. Tujuan penelitian ini untuk mengidentifikasikan kesuksesan sistem informasi penerimaan mahasiswa baru (SI-PMB) online dan variabel-variabel yang mempengaruhinya. Model DeLone McLean IS Success model digunakan dalam penelitian ini, dengan komponen variabel seperti: information quality, system quality dan service quality. Analisis data yang digunakan adalah model struktural dengan alat analisis Partial Least Square (PLS)  menggunakan software Smart PLS. Hasil dari penelitian diperoleh hubungan variabel Information Quality à User Satisfaction, dengan nilai t statistik 0,324, hubungan variabel Service Quality àUser Satisfaction, nilai t statistic 2,530, dan hubungan variabel System Quality à User Satisfaction, nilai t statistik 3,107, sehingga dapat disimpulkan bahwa terdapat hubungan positif dan siginifikan antara variabel system quality dan user satisfaction, terdapat hubungan positif dan siginifikan antara variabel service quality dan user satisfaction.  Hubungan variabel User Satisfaction à Net Benefits, nilai t statistik 8,708 menyatakan bahwa ada hubungan positif dan siginifikan antara variabel kepuasan pengguna (user satisfaction) dengan manfaat-manfaat bersih (net benefit).
Perancangan Jaringan Femtocell Pada Jaringan 4G LTE Di Gedung Rektorat Universitas Riau
Authors: Syam Ahmad Mudhhirulhaq , Junianto Daniel , Anggreani Dyan , Suganda Ilham Ferdian , Rahayu Yusnita
Published: May 2020

Makalah ini membahas perancangan jaringan indoor 4G LTE pada Gedung Rektor Universitas Riau menggunakan software aplikasi desktop Radiowave Propagation Simulator (RPS) 5.4. Perancangan jaringan indoor menggunakan model propagasi COST 231 Multi-Walls. Berdasarkan perhitungan area cakupan menggunakan model propagasi COST 231 Mulit-Wall yang telah dilakukan, dibutuhkan sebanyak 6 Femtocell Access Point (FAP) di setiap lantai. Analisis yang berhasil diperoleh dalam desain skenario posisi FAP pada tengah ruangan secara sejajar pada setiap lantai dengan level daya rata-rata -64,93 dBm dan SIR 6,72 dBm. Perancangan jaringan Femctocell 4G LTE menggunakan software RPS 5.4 dan model propagasi COST 231 Multi-Walls Mode dapat diterapkan ke Gedung Rektorat Universitas Riau.
Antibacterial effect of cinnamon essential oil (Cinnamon cassia) in different concentration towards Streptococcus sanguis
Authors: Hajanajumudin Hanizul , Satari Mieke Hemiawati , Setiawan Ame Suciati
Published: May 2020

Introduction: Streptococcus sanguis is a type of normal bacteria found in the oral cavity, particularly in plaque on tooth surfaces and can also be found in saliva, buccal mucosa, tongue and gingival sulcus. At present, the usage of herbal remedy for reducing plaque in oral cavity has been implemented widely and one of the herbal remedy used is cinnamon essential oil. The purpose of this study is to prove that there are differences in the antibacterial activity of cinnamon essential oil with different concentrations against Streptococcus sanguis. Methods: The study was performed using laboratory experiments, in which the sensitivity of the Streptococcus sanguis bacteria from the saliva of 10 KPBI batch 2006 dental students were tested in vitro against cinnamon essential oil by using Kirby-Bauer method. Results: The study shows that the cinnamon essential oil has different antibacterial abilities in inhibiting the growth of Streptococcus sanguis in different concentrations. This is due to the element cinnamaldehyde and eugenol that they posses as their main constituent. There is a significant difference between the antibacterial effects of Cinnamon cassia essential oil in different concentrations towards Streptococcus sanguis. Conclusion: Cinnamaldehyde and eugenol has been proved to have antibacterial effect towards wide variety of bacteria including Streptococcus sanguis.
Difference in the salivary pH before and after consumption of vitamin C lozenge on preclinical student of Faculty of Dentistry Universitas Padjadjaran
Authors: Sopannata Nirmala Trihasmana , Haroen Edeh Roletta , Richata Tuty Sutini
Published: May 2020

Introduction: Vitamin C lozenge can increase pH saliva. Increasing saliva pH is cause saliva works as a buffer that can neutralize the acidity of vitamin C. The purpose of this research was to find  the difference saliva pH before and after sucking vitamin C tablet. Methods: The research was carried out with quasi-experiment, using purposive sampling method and Paired t Test. This research was conducted on 30 students of the Faculty of Dentistry of Padjadjaran University, ranging 18-23 years of age. The research was carried out by measuring salivary pH before and after sucking vitamin C tablet. Results: Research result indicates that the average difference of salivary pH after sucking vitamin C tablet is 0.42 with standard deviation ±0,189. From statistic results   T calc 12,282 > T table 2,05  Ho is rejected, H1 is accepted. Conclusion: The research conclusion shows that there is a significant difference on saliva pH before and after sucking  vitamin C tablet lozenge on preclinical student of Faculty of Dentistry Padjadjaran University.
The difference of sweet taste threshold before and after using mouthwash containing zinc sulfate
Authors: Janarikamain Agung Ayu Dewi , Haroen Edeh Roletta , Dardjan Murnisari
Published: May 2020

Introduction: Mouthwash containing zinc sulfate could reduce the ability of tasting sweetness temporarily. Zinc sulfate is an example of a zinc compound which is the active ingredient in mouthwash. Zinc sulfate is added in mouthwash as an antiplaque and astringent material that gives a cleaning on the mouth. This study aimed is to analized differences of sweet taste threshold changes data before and after using mouthwash containing zinc sulfate. Methods: The study was using quasi experimental study. Study sample was collage students of Dentistry Faculty of Padjadjaran University totally 30 sample ages between 18-25 years old men and women took based on purposive sampling. Murphy method was applied to measure the threshold of sweet taste perception and identification before and after using mouthwash containing zinc sulfate. Results: The result of statistically shows the average value of sweet perception threshold before and after using mouthwash containing zinc sulfate are 0.0046 M and 0.0128 M with standard deviation 0.0047 and 0.0084. Sweet identification threshold before and after using mouthwash containing zinc sulfate are 0.0164 M and 0.0248 M with standard deviation 0.0089 and 0.0082. Conclusion: There is difference of sweet taste threshold  before and after using mouthwash containing zinc sulfate.
Differences in blood pressure before and after consuming cucumber juice (Cucumis sativus) in women aged 30-40 years
Authors: Franklin Martin , Haroen Edeh Roletta , Tjahajawati Sri
Published: May 2020

Introduction: Cucumber contains pottasium that can decrease blood pressure. This study was implemented to obtain data about the difference in blood pressure before and after consuming cucumber essence (Cucumis sativus) at women aged 30-40 years. Aim of this research is to analyzed difference s of blood pressure between before and after consuming cucumber essence (Cucumis sativus) at women aged 30-40 years. Methods: This study was a quasi-experimental with pair measurement statistic data test. Total samples of this study were 30 women at RW 02, Sukawarna district, Sukajadi, house of the village-head. Results: the average of systole before consume cucumber essence was 119,29 mmHg and after to be 115,09 mmHg. The average of diastole before consume cucumber essence was 80,91 mmHg and after to be 78,16 mmHg. Statsitic analysis showed if α = 0,05 (t0,975) value of tcalc both systolic and diastolic blood pressure > ttable so that H0 rejected and H1 accepted. Conclusion: this study showed a difference in blood pressure between before and after consuming cucumber essence (Cucumis sativus) at women aged 30-40 years.
The comparison of secondary caries between class I amalgam and class I composite restoration
Authors: Zubair Nur Hafizah Hanem , Sukartini Endang , Hayati Ayu Trisna
Published: May 2020

Introducion: Secondary caries or recurrent caries is a lesion which is observed under or around the margins or surrounding walls of an existing restoration. Amalgam has been the restorative method of choice for many years due to its low cost, easy application, strength, durability, and bacteriostatic effects. he need for restorative materials that bear similarity with natural tooth tissue such as composite resins, has increased.The aim of this study is to comparison the occurrence of secondary caries on class I amalgam and class I composite restoration. Methods: The type of research was descriptive study in which 100 samples of each class I amalgam and class I composite from department of conservative dentistry, faculty of dentistry, Rumah Sakit Gigi dan Mulut were taken. The proportion of secondary caries in both amalgam and composite restorations was analysed. Results: The result showed that the proportion of secondary caries on amalgam was 0,38 and composite was 0,19, and then was analysed with two-sample z test. There were significant differences between proportions of secondary caries on class I amalgam and the proportion of secondary caries on class I composite restorations. Conclusion: There is a difference between the proportions of secondary caries on class I amalgam and class I composite restorations where the proportion is higher in amalgam restorations compared to composite.
Comparison of the upper, middle, and lower vertical facial height between Down syndrome and normal children
Authors: Mohammad Ali Nor Dayana , Hartanto Rudy , Gartika Meirina
Published: May 2020

Introduction: Down syndrome (DS) is a common genetic disorder also known as Trisomy 21.DS individuals have specific physical dysmorphism especially the face. The most common features and problems associated with Down’s syndrome  are characteristic facial features, cognitive problems, congenital heart disease, hearing problems, short stature, thyroid problems and Alzheimer’s disease. This study aims to determine the differences of the vertical facial height measurement (UFH, MFH and LFH) between DS and regular (R) children. Methods: The study is a Cross-sectional analytical. Subjects are 6-13 years of age, with a total of 20 DS children (10 males; 10 females) of selected Sekolah Luar Biasa-C (SLB- Cs) and 160 R school children (80 males; 80 females) from selected Sekolah Dasar Negeri (SDNs) in Kota Bandung. Subjects selected using the three levels Multi stage cluster sampling. Measurements taken were upper, middle and lower facial height with each measurement taken three times. Data was analysed using the t-test and p-value. Results: UFH in DS males are 5.623, 5.986, 6.352, 6.396, 6.585, 6.747,7.109; MFH 3.325, 3.456, 3.457, 3.646, 3.611, 3.720, 3.716 and LFH are 4.163, 4.283, 4.235, 4.771, 4.850, 4.979, 5.132. UFH in R males are 5.924, 6.029, 6.223, 6.362, 6.476, 6.725, 6.903, 7.366; MFH 3.942, 3.998, 4.103, 4.148, 4.175, 4.247, 4.463, 4.534 and LFH 4.509, 4.658, 4.882, 5.058, 5.167, 5.450, 5.532, 5.606. In DS females UFH are 5.745, 5.912, 5.986, 6.394, 6.339, 6.778; MFH 3.575, 3.704, 3.711, 3.768, 3.749, 3.865 and LFH 4.49, 4.552, 4.646, 4.909, 5.034, 5.039. UFH for R females 6.062, 6.167, 6.243, 6.308, 6.476, 6.515, 6.799, 6.965; MFH 3.700, 3.863, 3.981, 4.084,4.091, 4.116, 4.191, 4.221 and LFH 4.576, 4.702, 3.764, 4.998, 5.156, 5.326, 5.374, 5.552 (in cm). Conclusion: There are significant differences with the MFH and LFH between DS and R children and UFH differences is non significant between these two populations.
Complication occurs after odontectomy of mandibular third molar
Authors: Busra Dicca Neldi , Karasutisna Tis , Yuza Abel Tasman
Published: May 2020

Introduction: The average age for completely eruption of the mandibular third molar is age 20-25. The eruption of mandibular third molar sometimes prevented by several factors, caused this tooth becomes impacted. All impacted third molar should be removed with minor surgery, which called odontectomy. Several complications and complaint are accompanied with extraction of impacted third molar. The purpose of this study was to determine the prevalence rate of complications post-odontectomy of mandibular third molar, based on genders, age of the patients, the classification of impactions, and the day of postoperative control. Methods: The characteristics of this study was a descriptive survey that collected the secondary data from the medical records, which used the research papers to collect the data. Results: The results of this study show that there are 545 medical records of the patient included to the study, 62.7% complications occur in women. Complications often occur in age groups over 30 years (56.3%). Conclusion: Most of complications occur in C position in class I, II, and III of Pell and Gregory classification. The most complications is oedem on the first day after surgery (43.1%) and on the day of sutures opened (12.3%).