bluuebunny/crossref_metadata_2025 huggingface dataset:
Vivências e reflexões: Fluxo e contrafluxo na inclusão de estudantes TEA em uma escola do Distrito Federal
Authors: Pinto Patricia de Siqueira , Schlünzen Junior Klaus
Published: January 2025

O presente artigo analisa os fluxos e contrafluxos no processo de inclusão de estudantes com Transtorno do Espectro Autista (TEA), com ênfase naqueles de nível 3 de apoio, em uma escola pública do Distrito Federal, com base em vivências e observações realizadas pela autora no contexto escolar. Esta pesquisa integra uma dissertação de mestrado em andamento, intitulada Trajetória da Inclusão de Estudantes com Transtorno do Espectro Autista (TEA): Experiências na Transição entre Classes Inclusivas e Especiais, que busca aprofundar a compreensão sobre os desafios, as práticas e os movimentos entre classes inclusivas e especiais, contribuindo para reflexões acerca da efetividade do processo inclusivo.A pesquisa destaca os desafios enfrentados no percurso de inclusão, evidenciando fatores que contribuem para movimentos de avanço (fluxos) e retrocesso (contrafluxos), como a falta de professores capacitados, de formação continuada, de monitores em número suficiente e de uma infraestrutura adequada. Por outro lado, propõe a adoção de metodologias inclusivas, como o Desenho Universal para a Aprendizagem (DUA), e práticas humanizadas para minimizar barreiras e favorecer a permanência dos estudantes na Classe Comum. O estudo reflete sobre a necessidade de compreender as razões que levam ao contrafluxo, buscando estratégias para evitá-lo e promover uma inclusão mais eficaz e equitativa. Reconhece, ainda, a importância de ajustes sensíveis e individualizados, considerando, em alguns casos, a Classe Especial como alternativa quando os recursos da Classe Comum se mostram insuficientes para garantir o bem-estar e o desenvolvimento do aluno.
ESTIMATIVAS DE FREQUÊNCIA DE TUBERCULOSE LATENTE E DOENÇA EM PESSOAS VIVENDO COM HIV, ATENDIDAS EM SERVIÇO DE REFERÊNCIA, EM GOIÁS
Authors: Rodrigues Bruna Sousa , Goerck Débora , Silva Flávio Henrique Rodrigues da , Souza Eric Mendes de , Cardoso Késia Priscila Omena , Pereira Henrique de Lacerda , Pires Telma Sousa , Turchi Marília Dalva , Amaral Waldemar Naves do
Published: January 2025

OBJETIVO: o objetivo deste estudo é estimar a frequência de infecção por M. tuberculosis latente e o risco de adoecimento em pessoas vivendo com HIV, acompanhadas em serviço especializado, em Goiás, além de avaliar o risco de evolução da forma latente para a forma ativa da doença nessa população. METODOLOGIA: neste estudo de coorte retrospectiva, a população foi composta por indivíduos HIV positivos acompanhados em serviço especializado. Foi realizada revisão de prontuários médicos e posterior análise dos dados obtidos, avaliando-se a prevalência e incidência de Tuberculose com intervalo de confiança (IC) de 95% p<5%. O projeto foi submetido e aprovado pelo Comitê de Ética em Pesquisa do Hospital das Clínicas da Universidade Federal de Goiás.  RESULTADOS: Dentre uma população de 85 pessoas, foram identificados dois casos de Tuberculose ativa, determinando uma prevalência de 2,4% (IC95% 0,4 a 7,6%) e dois casos de Tuberculose latente, apontando também uma prevalência de 2,4% (IC95% 0,1 a 5,8%). Não houve casos incidentes. CONCLUSÃO: A frequência de infecção por M. tuberculosis latente em PVHA observada foi menor do que a esperada.
IMPLEMENTASI PROGRAM PENGEMBANGAN SDM UNTUK MENINGKATKAN EFEKTIVITAS PENGELOLAAN ASET DAN TANGGUNG JAWAB KARYAWAN SMA NEGERI 2 MUARA BELITI
Authors: Leo Tarnando  , Rusdiyanto  , Sriekowati
Published: January 2025

Manajemen aset sekolah yang efektif merupakan aspek krusial dalam mendukung mutu pendidikan. Penelitian ini bertujuan untuk menganalisis pelaksanaan program pengembangan sumber daya manusia (SDM) dalam meningkatkan efektivitas pengelolaan aset dan tanggung jawab pegawai di SMA Negeri 2 Muara Beliti. Penelitian ini dilatarbelakangi oleh permasalahan rendahnya kesadaran dan tanggung jawab pegawai dalam memelihara aset sekolah, dimana sekitar 65% aset sekolah tidak mendapatkan perawatan dan pemeliharaan yang memadai. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Pengumpulan data dilakukan melalui observasi partisipatif, wawancara mendalam dengan informan kunci (kepala sekolah, wakil kepala sekolah, kepala tata usaha, guru, dan staf), dan studi dokumentasi. Analisis data menggunakan model interaktif Miles dan Huberman yang meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Keabsahan data dipastikan melalui triangulasi sumber, metode, dan waktu, serta member checking dan audit trail. Hasil penelitian menunjukkan bahwa pelaksanaan program SDM memegang peranan krusial dalam meningkatkan efektivitas pengelolaan aset sekolah. Program SDM yang sistematis dan berkelanjutan terbukti efektif dalam meningkatkan kesadaran dan kompetensi pegawai dalam pengelolaan aset. Temuan utama penelitian ini mengidentifikasi tiga area penting: (1) perlunya program pelatihan terstruktur, (2) pentingnya membangun kesadaran kolektif, dan (3) urgensi mengembangkan sistem dokumentasi dan pemantauan yang efektif. Penelitian ini menyimpulkan bahwa keberhasilan program HRD sangat bergantung pada dukungan dan komitmen semua pemangku kepentingan sekolah. Penelitian ini merekomendasikan pengembangan program pelatihan berkala, pembentukan sistem pemantauan yang efektif, dan alokasi anggaran khusus untuk pengembangan sumber daya manusia yang berkelanjutan.
DAMPAK RASIO KEUANGAN DAN KENAIKAN TARAF HIDUP TERHADAP KINERJA KEUANGAN PERUSAHAAN SEKTOR KONSUMSI DI INDONESIA
Authors: Wiarsih Febriani  , Dadi Kuswandi
Published: January 2025

Penelitian ini bertujuan untuk menganalisis dampak rasio keuangan dan kenaikan taraf hidup terhadap kinerja keuangan perusahaan di sektor konsumsi. Rasio keuangan yang dianalisis meliputi rasio lancar (current ratio), rasio cepat (quick ratio), dan rasio hutang terhadap aset (debt-to-assets ratio), sementara kenaikan taraf hidup diukur melalui pendapatan per kapita. Data diperoleh dari laporan keuangan perusahaan dan indikator ekonomi selama lima tahun terakhir. Hasil analisis menunjukkan bahwa rasio lancar memiliki pengaruh positif signifikan terhadap return on assets (ROA), sedangkan rasio cepat menunjukkan pengaruh negatif signifikan. Rasio hutang terhadap aset tidak menunjukkan pengaruh signifikan terhadap ROA. Pendapatan per kapita berpengaruh positif signifikan, menunjukkan bahwa daya beli masyarakat memperkuat kinerja keuangan perusahaan. Penelitian ini memberikan wawasan tentang pentingnya pengelolaan rasio keuangan yang seimbang dan strategi yang adaptif terhadap dinamika sosial-ekonomi.
PELATIHAN STRATEGI BRANDING UNTUK PENGEMBANGAN EKONOMI KREATIF BERBASIS KEARIFAN LOKAL
Authors: Abednego Priyatama  , Supiani  , Ardhy Lazuardi  , Abdul Rahman Agung Ramadhan  , Nugroho Eko Aprianto , Natallios Peter Sipasulta
Published: January 2025

This Community Service Program aims to provide training on branding strategies for developing creative economies based on local wisdom. Conducted by Universitas Gunadarma in collaboration with the Young Indonesian Lecturers Association (ADMI), the program utilizes a multidisciplinary approach encompassing 10 fields of study, such as management, engineering, and communication. The training integrates theory and practice, leveraging information and communication technology (ICT) to support local entrepreneurs in maximizing their cultural and local potential. The program enhances the competitiveness of local products through strong brand identities, digital marketing strategies, and the development of soft skills such as creativity, adaptability, and collaboration. Through simulations and real-world case studies, participants are guided to design, test, and evaluate their branding strategies. The expected outcomes include improved local brand quality, growth of the creative economy, and strengthened cultural identity, which positively impact the sustainability of regional economies.
PENGARUH HARGA DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN MASKER SENSI DUCKBILL
Authors: Nonik
Published: January 2025

Tujuan penelitian ini adalah untuk mengetahui pengaruh harga dan kualitas produk terhadap keputusan pembelian pada PT . Arista Latindo  yang memproduksi Masker Sensi dengan seri Duckbil. Metode penelitian menggunakan data primer kuantitatif dengan tahap uji yang dilakukan adalah uji instrumen, uji asumsi klasik, regresi, koefisien determinasu dan uji hipotesis. Hasil Penelitian ini berpengaruh signifikan variabel Harga (X1) dan kualitas produk (x2) terhadap keputusan pembelian dengan Harga(X1) memperoleh nilai 2,642 dengan nilai signifikan 0,010 dan kualitas produk(X2) memperoleh 5,376 dengan nilian signifikan 0,000 yang artinya Harga (X1) dan Kualitas Produk (X2) secara bersama-sama mempunyai pengaruh yang signifikan terhadap keputusan pembelian produk Masker Sensi Duckbill karena diperoleh nilai f hitung 33,550 > f tabel 3,09 dan nilai signifikasi adalah sebesar 0,000 < 0,05.
PENGARUH BAURAN PEMASARAN TERHADAP LOYALITAS PELANGGAN CHICAGO FRIED CHICKEN, PERUMNAS 1 BEKASI
Authors: Sri Rahayu Puspita Sari  , Ratih Fitri Yatun
Published: January 2025

Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh promosi, harga, produk dan lokasi terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Data yang digunakan adalah data primer, dengan menggunakan kuesioner yang disebar kepada 120 pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Teknik pengambilan sampel menggunakan purposive sampling. Alat analisis yang digunakan adalah uji validitas, uji reliabilitas, uji normalitas, analisis regresi linear berganda, uji determinan, uji f dan uji t. Hasil penelitian menunjukkan Produk tidak berpengaruh terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Harga berpengaruh terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Promosi berpengaruh terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Tempat tidak berpengaruh terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi. Produk, harga, promosi dan tempat secara Bersama-sama terhadap loyalitas pelanggan Chicago Fried Chicken, Perumnas 1 Bekasi
EPIGENÉTICA DO DESEMPENHO COGNITIVO HUMANO
Authors: Neto Oriel Pereira dos Santos , Umeno Guilherme Minaro Costa , Santos Kayo Phelipe de Melo , Martins Júlio Carneiro Vieira , Reis Miguel Ferro , Tavares Alessandra de Castro , Silva Antonio Márcio Teodoro Cordeiro
Published: January 2025

Este artigo tem como seus objetos de estudo os fatores epigenéticos envolvidos na expressão da cognição humana e busca oferecer uma compilação do conhecimento científico acerca dos aspectos epigenéticos associados à manifestação cognitiva. Nesse ínterim, foi realizada uma revisão de literatura com a coleta de 21 artigos produzidos entre 2018 e 2024, que apresentam como constatações principais os fatos de que, a partir de modificações epigenéticas, provocadas por fatores ambientais, nos padrões de metilação, de acetilação, de histonas e de expressão dos miRNAs, observam-se impactos na expressão intelectual individual que podem se relacionar direta ou indiretamente a estes mecanismos epigenéticos ou então a patologias neurológicas como o Alzheimer. Logo, com a compreensão destes fatores cognitivos, tem-se o cerne para pesquisas de terapias que visem a manutenção cognitiva com o envelhecimento.
Analysis Of Solitary Confinement In Detention Centers In Ecuador
Authors: Granja Z Diego Francisco , Villacrés Hernández Carlos Israel , Montenegro Bósquez Israel Emiliano , Espín Meléndez María Cristina
Published: January 2025

This study addresses the issue of the use of solitary confinement as a disciplinary sanction in detention centers in Ecuador, a practice that, despite being regulated by national and international norms, continues to result in serious human rights violations. The objective of the study was to analyze solitary confinement in Ecuadorian penitentiaries, evaluating its impact on inmates and the legal provisions that regulate it. To achieve this, inductive and critical-analytical methods were used, examining specific cases and applying a socio-legal approach based on constitutional regulations and international human rights instruments. The results revealed that, in practice, solitary confinement is frequently and abusively employed, without proper judicial control or medical supervision, which severely affects the physical, psychological, and moral integrity of inmates. Additionally, a disconnect was identified between the normative provisions that prohibit prolonged solitary confinement and their effective implementation in penitentiaries. In conclusion, the study determined that it is necessary to reform the Ecuadorian penitentiary system to ensure respect for the human rights of inmates, improve judicial oversight, train prison staff in non-coercive techniques, and strengthen rehabilitation programs, with the aim of reducing the use of solitary confinement and promoting the social reintegration of inmates
Environmental Protection: A Fundamental Right or a Social Objective? Comparative Constitutional Overview
Authors: Gera Anton
Published: January 2025

The protection of the environment is at the center of the current political debate in Europe and more widely, since the protection of human health is inevitably linked to the health of the environment. The relationship between environmental pollution and human health has been scientifically proven. The inclusion of environmental protection as a fundamental right in the Constitution on the one hand is very important because it affects the orientation and direction of the work of the parliament in relation to environmental policies in the future, while on the other hand it prevents the hegemony of the parliamentary majority in the implementation of some production policies to the detriment of the environment and therefore to the detriment of the health of the country's citizens. Initially, in this paper, the author will focus on the concept and importance of environmental protection, to continue later with the sources of environmental law at the international and national level. In this work, the question that was asked at the beginning of the time will be answered, that is, if the protection of the environment is a right that we can demand its respect in court or simply a social objective that the state wants to realize within its possibilities. I am sure that in the time of globalization, the modern lawyer cannot ignore the comparative analysis, since it now constitutes an essential analytical point of view for it. For this reason, the author will analyze environmental law in the comparative dimension, based mainly on the Constitutions of the countries of the European Union, an organization in which Albania wants to join in the not too distant future. The comparative method is a necessary tool to better understand the complexities arising from the globalization of law, which is characterized by the intermingling of different social, political and economic interests.
 
 
Received: 29 June 2024 / Accepted: 21 July 2024 / Published: 29 July 2024
Comparative Pathogenicity of Meloidogyne enterolobii and Meloidogyne incognita in Cotton Cultivars
Authors: Asmus Guilherme , Galbieri Rafael , de Araujo Andre Luiz Xavier , Belot Jean-Louis
Published: January 2025

Meloidogyne enterolobii (Me) is a nematode that has recently been observed in cotton. Initial observations indicate that cotton cultivars resistant to Meloidogyne incognita (Mi) are susceptible to Me, but the reproductive capacity and ability to cause damage by Me compared to Mi is unknown. The objective of this study was to assess the reproductive capacity and ability to cause damage by Mi and Me at different population densities in two cotton cultivars. The study included two greenhouse experiments in which two cotton cultivars, resistant and susceptible to Mi, were inoculated with six increasing population densities of Me and Mi. The genetic resistance of cotton to Mi given by quantitative trait loci of the q-Mi11 and q-Mi14 genes is ineffective against Me. The Mi-resistant cotton cultivar showed a similar gall index to the Mi-susceptible cultivar when inoculated with Me. The mean gall index with Me was significantly higher than that with Mi on the Mi-resistant cotton cultivar. Based on the number of nematodes per root mass and the reproductive factor, Me showed a higher reproductive capacity than Mi on cotton. Increasing Me population densities linearly reduced the height and dry matter production of aboveground biomass in the Mi-resistant cotton cultivar. However, neither Meloidogyne species affected leaf chlorophyll content and photosynthetic rate of the cotton plants.
projektpedagógia és a Digitális Témahét
Authors: Főző Attila László
Published: January 2025

A projektmódszer számos változáson esett át az évszázadok alatt, mire a mai értelemben vett projektpedagógiáról beszélhetünk. A projektoktatásban több modell, megközelítés és definíció látott napvilágot, amelyek ma is sokatmondóak. Az időről időre megugró népszerűségű projektoktatás látszólag sokat megtartott a XX. század eleji gyökereiből, de a társadalmi, technológiai változások miatt a fogalmak, a célok jelentése is megváltozott. A Digitális Témahét, mint a legnagyobb magyarországi, a tanév rendjében szereplő digitális pedagógiai program, immár egy évtizede a projektpedagógia eszközeivel segíti elő a tanulók és a pedagógusok digitális kompetenciájának fejlesztését. A projektpedagógia fejlődésének néhány állomását ismertetve, a tanulmány bemutatja a Digitális Témahetet és annak projektoktatási modelljét, miközben kitér a digitalizáció világában kiemelt fontosságú készségek fejlesztésére is.
Digitális Témahét (M)ai világunk
Authors: Tuboly Rita
Published: January 2025

A Rábapatonai Petőfi Sándor Általános Iskola pedagógusai és tanulói kilencedik alkalommal csatlakozott a Digitális Témahéthez. A projekt célja a környezeti nevelés és a környezettudatosság erősítése volt, különböző korosztályok számára kidolgozott tevékenységekkel. Az 1-2. osztályosok Hany Istók legendájával ismerkedtek meg, míg a 3-4. osztályosok újrahasznosított anyagokból padlórobotpályát építettek. Az 5-6. osztályosok a mesterséges intelligencia szerepét vizsgálták a biodiverzitás megőrzésében, a 7-8. osztályosok pedig a fenntartható horgászat és a védett halak témakörével foglalkoztak. A projekt során a digitális és szociális kompetenciák, a kreativitás és a kritikai gondolkodás fejlesztésére helyeztük a hangsúlyt. A jógyakorlat bemutatásának célja, hogy megmutassuk, hogyan lehet egy egész intézményen átívelő témahetet végrehajtani.
Felsőoktatás és óvoda együttműködése a Digitális Témahéten
Authors: Kubinger-Pillmann Judit
Published: January 2025

Egy különleges projekt egyetem és óvoda között, ahol célul tűztük ki, hogy az óvodás korosztály számára érthetővé tegyük a mesterséges intelligencia fogalmát. Ehhez egy saját készítésű robot volt segítségünkre. A robot tudásának formálódását az óvodások napról napra követhették, hiszen ők tanították az eszközt. Játékos formában komplex módon fejlesztettük az óvodások digitális kompetenciáját, miközben többek között a matematikai, a környezeti, az anyanyelvi kompetenciaterületeket is alakítottuk. A projekt során együtt dolgozott egyetemi mentor, óvodapedagógus és óvodapedagógus hallgató.
PENGARUH KEPERCAYAAN, KEMUDAHAN DAN KUALITAS INFORMASI TERHADAP KEPUTUSAN PEMBELIAN SECARA ONLINE DI APLIKASI SHOPEE MAHASISWA FAKULTAS ADMINISTRASI IAKSS MUARA BUNGO
Authors: Baqiyah Sakinah Nurul , Jesika Silvia , Juniarsih Delvita , Nasir M
Published: January 2025

Salah satu faktor pendukung seseorang melakukan keputusan pembelian adalah dengan mengedepankan rasa kepercayaan, karena kepercayaan merupakan faktor utama membeli sebuah produk. Kemudahan juga tidak kalah pentingnya karena mampu menjadikan konsumen lebih mudah memilih produk. Selain itu, kualitas informasi merupakan bagian dan peran yang sangat penting didunia perbelanjaan online dan juga mampu mempengaruhi pada keputusan pembelian konsumen. Penlitian ini bertujuan untuk mengetahui pengaruh kepercayaan, kemudahan dan kualitas informasi terhadap keputusan pembelian secara online di aplikasi shopee (studi pada Mahasiswa Institut Administrasi dan Kesehatan Setih Setio Muara Bungo).????????? Metode yang digunakan dalam penelitian ini adalah metode asosiatif dengan pendekatan kuantitatif dan teknik pengumpulan data dalam penelitian ini menggunakan kuesioner. Populasi pada penelitian ini adalah mahasiswa Fakultas Administrasi angkatan 2019 Institut Administrasi dan Kesehatan Setih Setio Muara Bungo yaitu sebanyak 182 Mahasiswa dan sampel dalam penelitian ini sebanyak 108 responden menggunakan teknik probability sampling dengan mettode simple random sampling.??????????? Berdasarkan hasil penelitian yang dilakukan menunjukkan bahwa terdapat pengaruh kepercayaan terhadap keputusan pembelian, yang memperoleh dari nilai t hitung (3,410) > t tabel (1,98304) dan nilai signifikan (0,001) < 0,05 maka keputusannya H1 diterima. Pengaruh kemudahan terhadap keputusan pembelian, yang memperoleh dari nilai t hitung (2,039) > t tabel (1,98304) dan nilai signifikan (0.044) < 0,05 maka keputusannya H2 diterima. Pengaruh kualitas informasi terhadap keputusan pembelian, yang memperoleh dari nilai t hitung (5,387) > t tabel (1,98304) dan nilai signifikan (0,000) < 0,05 maka keputusannya H3 diterima. Hasil uji koefisien determinasi (R2) memiliki pengaruh sebesar 0,765, hal ini menyatakan bahwa kepercayaan, kemudahan dan kualitas informasi mempengaruhi keputusan pembelian sebesar 76,5%. Maka diartikan bahwa variabel kepercayaan, kemudahan dan kualitas informasi berpengaruh terhadap variabel keputusan pembelian sebesar 76,5%, sedangkan sisanya sebesar 23,5% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
PENGARUH KEAMANAN DAN KEPERCAYAAN TERHADAP KEPUTUSAN PEMBELIAN SECARA ONLINE DI LAZADA
Authors: Antoni Feri , Ulum Panji , Burhanuddin Burhanuddin , Nasir M , Amili Zulfa Rojana
Published: January 2025

Perkembangan e-commerce saat sudah ini dapat digunakan sebagai media berbelanja, bahkan sudah semakin banyaknya keberadaan situs jual beli online? seperti Lazada. Namun belanja secara online dihadaakan pada permasalahan keamanan dan kepercayaan yang diberikan oleh online shop pada calon pembeli, sehingga memutuskan untuk melakukan pembelian secara online.?Tujuan penelitian ini untuk mengetahui pengaruh keamanan dan kepercayaan terhadap keputusan pembelian secara online di Lazada pada mahasiswa mahasiswa Institut Administrasi dan Kesehatan Setih Setio Muara Bungo. Penelitian Ini menggunakan metode analisis kuantitatif. Populasi dalam penelitian ini adalah mahasiswa Institut Administrasi dan Kesehatan Setih Setio Muara Bungo. Jumlah sampal dari 93 orang responden. Teknik pengumpulan data yang digunakan adalah observasi kuesioner, studi pustaka. Teknik analisis data yang digunakan adalah statistik deskriptif, uji instrumen berupa, uji asumsi klasik, uji regresi linier berganda dan serta uji hipotesis menggunakan analisis regresi linear berganda, uji T, uji F dan uji Determinan (r?)Hasil peneltian ini menunjukkan bahwa secara parsial terdapat pengaruh keamanan terhadap keputusan pembelian (H₁), terdapat kepercayaan terhadap keputusan pembelian (H₂), dan secara simultan terdapat pengaruh keamanan dan kepercayaan terhadap keputusan pembelian secara online di Lazada pada ?mahasiswa IAK Setih Setio Muara Bungo (H₃).
IMPLEMENTASI PROGRAM SUSTAINABLE DEVELOPMENT GOALS (SDGS) DESA DALAM MENANGGULANGI KEMISKINAN DI DESA SUNGAI LIMAU, KECAMATAN TABIR TIMUR, KABUPATEN MERANGIN
Authors: Al Afgani Usamah Izzah , Maros Asra'I , Dolly Fajar Ifan
Published: January 2025

This research aims to find out how the implementation and what are the obstacles in the SDGs Desa no poverty program in Tackling Poverty in Sungai Limau Village, Tabir Timur District, Merangin Regency. This research was uses descriptive research methods with a qualitative approach. The results showed that the Implementation of the Sustainable Development Goals (SDGs) Desa Program in reducily Poverty in Sungai Limau Village, Tabir Timur District, Merangin Regency has not been implemented properly. This would be seen from the 7 indicators of poverty, there were 4 indicators that have not been implemented properly and 3 indicator is well implemented. Next to the Sungai Limau Village Government in order to be able to make a RPJM Desa based on SDGs data and conduct socialization and data collection that is evenly distributed to each community.
PENGARUH KUALITAS PELAYANAN DAN CITRA PERUSAHAAN TERHADAP KEPUASAN KONSUMEN (Studi Pada Ekspedisi Sicepat Express Cabang Muara Bungo)
Authors: Andriani Popi , Tarjo Tarjo , Rusnaini Sasmita
Published: January 2025

Bisnis yang bekembang pesat saat ini salah satunya yaitu bisnis pengiriman barang. Oleh karena itu banyak perusahaan jasa pengiriman barang beroperasi yang menyebabkan perusahaan harus berkompetisi. Penelitian ini bertujuan untuk menguji adakah pengaruh kualitas pelayanan dan citra perusahaan terhadap kepuasan konsumen (Studi pada Ekspedisi Sicepat Express Cabang Muara Bungo).Metode penelitian yang digunakan adalah pendekatan kuantitatif dengan jenis penelitian deskriptif, teknik pengumpulan data menggunakan kuesioner, Populasi dalam penelitian ini yaitu seluruh konsumen Ekspedisi Sicepat Express Cabang Muara Bungo yang berjumlah 150 konsumen. Teknik pengambilan sampel penelitian menggunakan teknik random sampling dengan rumus yang direkomendasikan oleh hair et al. Analisis data yang digunakan analisis regresi linear berganda menggunakan aplikasi SPSS versi 20.Hasil penelitian menunjukan bahwa kualitas pelayanan (X1) memiliki nilai t hitung 9,240 > t tabel 1.976, dengan tingkat signifikansi sebesar 0.000 ≤ 0.05 maka kualitas pelayanan berpengaruh signifikan terhadap kepuasan konsumen di Ekspedisi Sicepat Express Cabang Muara Bungo. Citra perusahaan (X2) memiliki nilai t hitung 1,508 < t tabel 1.976, dengan tingkat signifikansi sebesar 0.134 > 0.05 maka citra perusahaan tidak berpengaruh signifikan terhadap kepuasan konsumen di Ekspedisi Sicepat Express Cabang Muara Bungo. Kualitas pelayan dan citra perusahaan berpengaruh signifikan terhadap kepuasan konsumen di Ekspedisi Sicepat Express Cabang Muara Bungo. Hal ini dapat dilihat dari nilai f hitung188,083 ≥ f tabel 3,06, dengan tingkat signifikansi sebesar 0.000 ≤ 0.05, maka dapat disimpulkan H4 diterima.
Reclamation and Post-Mining Management at PT. XYZ East Kalimantan Province
Authors: Vico Julyas , Sibarani Mentiana
Published: January 2025

East Kalimantan Province is one of the largest coal producers in Indonesia. Mining activities often have a negative impact on the environment, making it important to manage reclamation effectively. The purpose of this study is to understand and analyze the management of reclamation and post-mining at PT XYZ to minimize the negative impacts of mining activities. This research uses a case study method with a qualitative descriptive approach. Data was collected through interviews, observation and documentation. The informants involved were purposively selected to gain an in-depth understanding of reclamation practices. The results show that PT XYZ routinely conducts reclamation and post-mining activities. However, the implementation has not been fully optimized due to various constraints, including the lack of a good reclamation plan, adequate funding and the involvement of all relevant parties. To minimize the negative impacts of mining activities, a strong commitment from the company, community and government is needed to create sustainable and environmentally friendly mining operations. This study provides important insights into reclamation practices and managerial approaches that can be adopted by other companies.
Editorial
Authors: De Santis Lucia
Published: January 2025

Through basic research, it is possible to obtain information with important clinical and therapeutic implications. The application of assisted reproduction techniques has clearly benefited the treatment of infertility, but many aspects that regulate the biology of reproduction remain totally unknown or still little investigated. The most important characteristic of research in modern medicine is precisely its translational nature and its ability to discover molecular mechanisms and scientific approaches that can be used in fields other than those for which they were initially studied. A striking example is the birth, in virology, of m-RNA vaccines, whose use has paved the way for applications in the field of oncology.
The therapeutic promise of mesenchymal stem cells and their exosomes in treating polycystic ovary syndrome
Authors: Casoli Giovanni , Bevilacqua Arturo
Published: January 2025

Polycystic ovary syndrome (PCOS) is a common disorder of the female reproductive system. It is significantly associated with decreased fertility, and characterized by metabolic abnormalities such as hyperinsulinemia, insulin resistance, obesity, and hyperandrogenism. It is also associated with increased risk of type 2 diabetes, hypertension, and cardiovascular disease. Current therapies have limitations and are often ineffective, making it essential to explore new therapeutic approaches. Exosomes are extracellular membrane vesicles, released by cells, which play crucial roles in cell-to-cell communication. They transport various types of cargo, including lipids, proteins, mRNAs, miRNAs, and other noncoding RNAs. Since the cytokine effects of stem cells and their derived exosomes can offer protection against metabolic diseases, in this review we evaluate their potential use in the treatment of PCOS. KEY WORDS: PCOS, exosomes, infertility, mesenchymal stem cells.
Développement académique de médicaments de thérapie innovante (ATMP) en Belgique
Authors: Pouppez Céline , Bourgeois Jolyce , Hulstaert Frank , Vinck Imgard
Published: January 2025

Les médicaments de thérapie avancée (ATMP, Advanced Therapy Medicinal Products) sont des thérapies complexes basées sur des cellules, des gènes ou des tissus. À l’heure actuelle, ils sont surtout développés et utilisés pour le traitement de certaines formes de cancer ou de maladies génétiques. Les ATMP actuellement commercialisés par l’industrie sont peu nombreux et souvent proposés à un coût élevé, pouvant atteindre plusieurs millions d’euros par traitement. À la demande de plusieurs associations belges de lutte contre le cancer, le Centre Fédéral d’Expertise des Soins de Santé (KCE) a examiné comment optimiser le rôle des universités belges dans ce domaine, dans le but d’améliorer l’accès à ces médicaments pour les patients. Pour atteindre cet objectif, il sera indispensable que les acteurs académiques et les autorités disposent d’une expertise de pointe et collaborent de façon plus étroite. Par ailleurs, sachant que le développement de tels produits peut s’étendre sur de nombreuses années, il faut que le financement couvre une période suffisamment longue et soit moins fragmenté.
Digital Transformation Design
Authors: Lotter Dennis
Published: January 2025

Die Digitalisierung hat schon viele Branchen umgekrempelt, manche sogar vernichtet. Und sie wird nicht als Hype vorüberziehen. Vielmehr wird sie eher noch schneller, noch radikaler unser Leben verändern. Denn das, was wir bisher erlebt haben, war erst der Anfang. Aber wie bereitet man sich auf die bevorstehenden Umbrüche vor? Wie setzt man die digitale Transformation im Unternehmen in Gang? Welche Werkzeuge sind für die digitale Transformation hilfreich? Wie steuert man diese Transformation? Und vor allem: Was bedeutet digitale Transformation wirklich? Das neue Buch von Prof. Lotter gibt Antworten auf genau diese Fragen. Es liefert 33 fundamentale Prinzipien und Tools, mit denen sich die digitale Transformation gestalten lässt. Mit diesem Playbook lassen sich zukunftsrelevante Fähigkeiten identifizieren und die eigene Roadmap zur digitalen Transformation entwickeln. Denn erst wer die Mechanismen der digitalen Transformation verstanden hat, kann sie gestalten.
Der Code agiler Organisationen
Authors: Puckett Stefanie
Published: January 2025

Die Unternehmenskultur ist die größte Herausforderung und größter Stellhebel zugleich, wenn es darum geht, eine agile Organisation zu formen. Wie aber lässt sich das Konzept Organisationskultur auf handlungsrelevanter Ebene greifbar machen? Was macht eine agile Kultur aus? Was sind ihre Elemente? Wie formt und entwickelt sich diese Kultur? Wo sind die Ansatzpunkte und wo liegen Fallstricke? Was funktioniert in der Praxis wirklich? Pucketts Buch liefert Antworten auf diese Fragen und zeigt, wie sich die Unternehmenskultur gestalten und formen lässt. Dabei taucht es in die Organisationspsychologie ein und übersetzt die Erkenntnisse in praktische Handlungsempfehlungen. Auf Basis von Analysen agiler Organisationen und solcher in Transformation, wird der Code agiler Unternehmenskultur entschlüsselt. Die Kernelemente agiler Organisationskulturen werden definiert und anhand von Beispielen anschaulich beschrieben. Das Buch ist gefüllt mit Kultur-Hacks, praxiserprobten Tipps, Werkzeugen und Methoden. Puckett gelingt ein völlig neuer Blick auf den Begriff Organisationskultur. Denn es liegt in unseren Händen, die Kultur zu formen: Als Einzelne, als Team, als Führungskraft. Wir sind Unternehmenskultur! Dieses Playbook lädt zum Experimentieren und Gestalten ein und zeigt anschaulich, wie Organisationen der agile Wandel gelingt. „Ein äußerst nützliches Werkzeug für jeden, der sich in der kniffligen Welt des Kulturwandels in Organisationen besser zurechtfinden will.“ (Michael Wade, Professor bei IMD, Direktor des Global Center for Digital Business Transformation)
Clever visualisieren
Authors: Bütefisch Siegfried (Sigi)
Published: January 2025

Das Sketchnoting Workbook – von ganz einfach bis einfach genial Kann man Gedanken und Zusammenhänge einfach sichtbar machen? Ja, durchs Visualisieren mit sketch4effects. Clevere Visualisierungen »schießen« selbst Zahlen, Daten und Fakten durchs Herz ins Hirn! Das bringt mehr als nur als Flippcharts aufzuhübschen und dekorative Bildchen zu malen. Sketch4effects hilft dir beim Lernen, Erklären, Strukturieren, Inspirieren, Lenken, Präsentieren, Moderieren. Sigi Bütefisch zeigt dir in diesem Workbook, wie du Menschen visuell bewegst. Egal, ob du bis jetzt nur Mausbediener oder schon leidenschaftlicher Visualisierer bist. Schon die ersten Impulse und Übungen nutzen dir bei deinen täglichen Aufgaben. Alle Impulse bauen aufeinander auf und machen jede Zeichenfläche zur Bühne fesselnder visueller Storys rund um deine Themen. Storys, die helfen, mehr zu verstehen und besser verstanden zu werden. Am Ende dieses Buches wird »der Stift in der Hand«, egal, ob klassisch oder digital, für dich dein unverzichtbarer Zauberstab für bessere Ergebnisse sein. Mein Tipp: Hebe deine Visualisierungen, die im Laufe dieses Buches entstehen, auf. Du wirst dich beim Blick zurück über deine Visualisierungsfortschritte freuen – garantiert.
The European Union’s Push for Equality, Diversity and Inclusion (EDI) and Its Implications for Career Development: A Perspective on Skills and Competences
Authors: Bencivenga Rita , Campanini Vilhena Fernanda , Celeste Taramasso Angela
Published: January 2025

In today’s evolving labour market, career development requires a nuanced understanding of equality, diversity, and inclusion (EDI). This chapter examines how the European Union’s emphasis on EDI through gender equality plans (GEPs) and other policies necessitates a shift in the competencies required for career progression, particularly within the academic sector. It argues that individuals at all levels and roles in academic institutions must develop both formal and non-formal EDI competencies to remain competitive in their careers. To achieve this, we underscore the need for structured training and resources to equip all individuals in academia with the skills to promote EDI in the workplace, not just those in human resources or dedicated EDI offices. We do so by suggesting two main strategies: (i) developing EDI competencies at the individual level and (ii) creating or joining communities of practice to structure and operationalise knowledge and skill acquisition. These strategies are powerful tools to engage the broader academic community in EDI issues, providing individuals with the necessary resources and structure to develop essential competences, fostering personal and professional growth, and contributing to a more inclusive academic environment.
Perspective Chapter: Supporting Newly Graduated Nurses Transition to Practice
Authors: D. Kret Diane
Published: January 2025

Newly graduated nurses (NGN)s experience the Duchscher’s Stages of Transition and experience shock throughout these stages. Understanding the doing, knowing and being stages, allows key stake holders, like NPD specialists, preceptors, and nursing leadership have the knowledge they need to provide the proper support as the NGNs’ needs change with each stage. Simulation and standardized checklists provide preceptors and NPD specialists documentation and tracking of the NGNs progress and provides maintenance of these skills off orientation. A good mentorship that is fully supported by the organizations, provides emotional and clinical support to NGNs when needed to help them gain confidence as independent practitioners. The NPD specialist’s value extends beyond orientation with the support they provide in education of quality indicators that improve patient outcomes and thereby help to maintain the excellent practice of NGNs and current staff. Providing these resources to the NGNs, help them transition into independent practitioners.
Ovarian Cancer Screening
Authors: Mohamed Ali Nasr Abubakr
Published: January 2025

Ovarian cancer screening remains elusive in spite of the tireless efforts. The challenges faced include the prevalence of ovarian cancer and its impact on the positive predictive value of screening tests. Effective screening is highly needed in view of being the deadliest gynecological cancer with late presentation. The diversity of targeted population, low and high risk as well as the ambiguity in oncogenesis and shared origin by fallopian tubes and peritoneum are genuine obstacles in unifying a screening program for the heterogenous disease. The consensus does not recommend screening in low-risk populations. Evaluation of available screening tests in multiple trials did not prove reduction in mortality. There may be an increase in detection of early disease. However, the impact on mortality and quality of life is questionable. The screening tests including pelvic sonography, tumor markers, proteoms, mRNA, free DNA and symptom-based screening did not prove significant statistical power in view of the risky diagnostic testing with laparoscopy and significant possibility of false positive results. There is potential role for developments in the available tests and future developments including AI.
Approach to Peripheral Neuropathy
Authors: Shin Yong Chee , Alexander Mathew
Published: January 2025

Peripheral neuropathy is frequently encountered in the clinical setting by doctors of various specialties. Neuropathies can be approached based on the temporal profile, spatial pattern and pathology. There is a need for eliciting a focused history, co-morbidities, exposure to medications and toxins, family history and examination, electrodiagnostic testing and laboratory testing. The prevalence of neuropathy is based on epidemiological studies, and it is important to know the yield of etiological diagnosis, even after extensive investigations. Acute neuropathies include Guillain-Barre syndrome, porphyria, ICU-acquired paresis, neuropathies associated with systemic diseases, autoimmune diseases, nutritional, toxic and genetic disorders. It’s important to have knowledge about electro-diagnostic characteristics, the role of nerve biopsy in select cases, treatment, both disease-modifying and symptomatic and outcome.
Perspective Chapter: The Role of Human Resources Management in Employee Well-Being
Authors: Öngel Gökten , Taşkıran Erkan , Gençer Çelik Gülşah
Published: January 2025

The rules of the game have been changed for actors of business life due to the unpredictable and unforeseen impacts of COVID-19 pandemic. These changing conditions have reshaped the fierce competition and challenges among business establishments. The key to success in such an environment is attributed to the qualified labor force. However, the impact of difficult conditions has created significant and important effects not only on organizations but also on employees. Therefore, organizations need to focus on the well-being of their employees and ensure their health and increase their performance. Well-being refers to the totality of both mental and physical health of an employee. The main purpose of this chapter is to conceptually discuss the role of human resource management in ensuring employee well-being. Within the scope of the main purpose, the importance and necessity of the human resource department for the well-being of employees has been underlined.
The Optimal Cut-Points of Alanine Aminotransferase for Screening Metabolic Syndrome in Iranian Adults
Authors: Asgari Samaneh , Azizi Fereidoun , Hadaegh Farzad
Published: January 2025

Background: Studies have reported that the activity of alanine aminotransferase (ALT) is a key biomarker for screening liver cell damage, such as non-alcoholic fatty liver disease (NAFLD). Objectives: Since individuals with metabolic syndrome (MetS) are at high risk for NAFLD, we aimed to determine gender-specific ALT thresholds for screening MetS in the Tehranian population. Methods: We conducted a cross-sectional study from 2018 to 2022, involving 4,968 adults aged 20 - 70 years (2,732 females). Multivariable logistic regression analysis was performed to assess the association between ALT levels and the prevalence of MetS, as well as its individual components. Additionally, gender-specific ALT cut-off points were determined using the maximum Youden's Index. The area under the receiver operating characteristic curve (AUC) was calculated to derive thresholds and compare them with the previously introduced cut-off points for liver-related mortality in the U.S. population (US-LRM) (ALT > 19 U/L for females, > 29 U/L for males). We also examined the diagnostic performance of the derived cut-off points in 11 147 individuals (7,154 women) from the atherosclerosis risk in communities (ARIC) study as an external validation. Results: The odds ratio (OR) from the logistic regression analysis showed that each 5 U/L increase in ALT level was associated with an increased prevalence of MetS [19% for females and 8% for males] and its components (ranging from 7 - 19% in females and 3-10% in males; all P-values < 0.05). The suggested cut-off point for ALT in males was 21 U/L, with a sensitivity of 72.1% and specificity of 47.1%. For females, with a threshold of 18 U/L, the corresponding values were 57.9% sensitivity and 66.5% specificity. Compared to the US-LRM suggested cut-off points in the US population, the AUC of our suggested threshold increased in males (60% vs. 56%, respectively), while for females, it remained the same as in the pretest (≈ 62%). Using ARIC data, our suggested threshold showed nearly identical AUC values to the US-LRM threshold in females (58% vs. 57%, respectively), whereas for males, the highest AUC was observed for our suggested cut-off points (56%), followed by the mortality-related threshold (53%). Conclusions: The cut-off point for screening MetS among Iranian women was almost identical to the lower suggested threshold in American guidelines but was notably lower for defining abnormal ALT levels in males.
Umbilical Cord Zinc Levels and Neonatal Anthropometric Measures: A Cross-Sectional Study in Iran
Authors: Kaveh Mahbod , Darabi Marzieh , Sangsari Razieh , Moeini Roksana , Veysizadeh Maryam , Zarkesh Mohammad Reza , Shariat Mamak
Published: January 2025

Background: Zinc (Zn) is one of the trace elements in the body that, despite its low level, plays important roles in molecular and cellular activities. A few investigations have assessed the correlations between cord blood Zn levels and neonatal anthropometric measures; however, the results are conflicting. Objectives: The purpose of the present study was to investigate the relationships between the Zn level in the umbilical cord blood and the birth weight, height, and head circumference of term newborns. Methods: A cross-sectional study was conducted on full-term newborns in Tehran, Iran, in 2021. Neonates’ Zn levels in umbilical cord blood were evaluated. Data related to perinatal and neonatal variables such as the number of pregnancies (gravida), birth height, weight, and head circumference were recorded, and their relationships with umbilical cord Zn levels were assessed. P-values < 0.05 were considered statistically significant. Results: One hundred mothers with a mean age of 30.792 ± 5.908 years and a parity of 2.693 ± 1.181 were included. Of all the newborns, 68% were boys, and 2% had low birth weight. The mean level of cord blood Zn was 107.703 ± 27.843 µg/dL. Evaluating the correlations between cord blood Zn levels and maternal and neonatal qualitative variables, data analysis showed no relationships between Zn levels and neonatal sex (P = 0.70), low birth weight (P = 0.87), and maternal underlying disease (P = 0.49). Data analysis regarding correlations between quantitative variables also showed no significant correlations between cord blood Zn levels and birth weight (P = 0.466), height (P = 0.466), and head circumference (P = 0.925). Conclusions: Although adequate Zn levels were observed in all neonates, these levels did not significantly influence neonatal anthropometric measures or immediate health indicators. Further studies with larger sample sizes are recommended to provide more comparative data, particularly in relation to long-term growth outcomes.
COLORINDO E ASSEGURANDO O HABITAR
Authors: Alves Pereira Maria Cristina , Romano Daibert Júlia , Nascimento Adriana
Published: January 2025

Na contemporaneidade, a condição urbana está repleta de disputas, conflitos e violência urbana relacionados à estrutura político-econômica, à distribuição de renda e às históricas desigualdades socioespaciais. Gerados pela urbanização desordenada e carente de urbanidade, são visíveis impactos que evidenciam a concentração de problemas sociais em territórios específicos. O artigo tem como objetivo discutir e apresentar os resultados de uma transformação socioespacial ocorrida por meio da intervenção artística participativa na paisagem urbana. As transformações socioespaciais e culturais têm gerado impactos territoriais positivos, fortalecendo vínculos, inibindo a violência e fomentando a economia e a cultura locais. Ancorado na metodologia de estudo de caso exploratório qualitativo, o trabalho traz observações das etapas da coleta de dados da área estudada, com análise crítica. O estudo busca compreender os desdobramentos e consequências relacionados às melhorias urbanas e sociais sobre a redução da desigualdade social e a valorização da participação popular em suas etapas.

Na contemporaneidade, a condição urbana está repleta de disputas, conflitos, violência urbana relacionadas à estrutura político-econômica, à distribuição de renda e históricas desigualdades socioespaciais. Gerada por urbanização desordenada e sem urbanidade, há impactos visíveis evidenciando a concentração de problemas sociais em territórios específicos. O artigo visa debater e apresentar resultados a respeito de transformação socioespacial ocorrida via intervenção artística participativa na paisagem urbana. As transformações socioespaciais e culturais vêm gerando impactos territoriais positivos, fortalecendo vínculos, inibindo violências e fomentando a economia e cultura local. Ancorada na metodologia de estudo de caso, de caráter exploratório qualitativo, o trabalho reúne observações das etapas do projeto e coleta de dados da área estudada, com análise crítica. Com o estudo busca-se compreender os desdobramentos e as consequências positivas relacionadas à melhorias urbanas e sociais que culminam na redução da desigualdade social e na valorização da participação popular em suas etapas.