bluuebunny/crossref_metadata_2025 huggingface dataset:
PROFIL ASAM AMINO DAN ASAM LEMAK KERANG BULU (Anadara antiquata)
Authors: Abdullah Assadatun - , Nurjanah - - , Hidayat Taufik - , Yusefi Vitriyone -
Published: May 2024

Kerang bulu (Anadara antiquata) merupakan salah satu biota laut yang sampai saat ini keberadaannyabelum dimanfaatkan secara optimal. Penelitian ini bertujuan menentukan jenis dan jumlah asam amino danasam lemak kerang bulu. Komposisi kimia kerang bulu diuji dengan analisis proksimat. Kandungan asamamino pada daging dan jeroan kerang bulu dapat diuji menggunakan High Performanced Liquid Chromatografy(HPLC). Komposisi kimia daging kerang bulu terdiri atas kadar air 79,69%, abu 1,57%, lemak 2,29%, protein12,89%, dan karbohidrat 3,56%. Komposisi kimia jeroan kerang bulu terdiri dari kadar air 81,50%, abu 1,99%,lemak 4,60%, protein 10,13%, dan karbohidrat 1,78%. Kandungan asam amino yang paling tinggi pada dagingdan jeroan kerang bulu adalah asam glutamat dengan nilai 1,74% dan 1,22%. Asam amino yang terdapatdalam jumlah paling sedikit pada daging dan jeroan kerang bulu adalah histidin dengan nilai 0,15%. Asamlemak jenuh tertinggi yang terdapat pada daging utuh dan tanpa jeroan kerang bulu adalah asam palmitatdengan nilai 5,82% dan 5,67%. Asam palmitoleat adalah asam lemak tak jenuh tunggal tertinggi dengan nilai2,42% dan 2,36%. Asam lemak tak jenuh majemuk tertinggi pada kerang bulu adalah EPA dengan nilai 5,25%dan 4,06%.Kata kunci: asam amino esensial, asam amino non esensial, asam lemak, kerang bulu (Anadara antiquata)
AKTIVITAS ANTIBAKTERI EKSTRAK DAUN BAKAU HITAM (Rhizophora mucronata) TERHADAP BAKTERI PENYEBAB DIARE
Authors: Tarman Kustiariyah - , Purwaningsih Sri - , Negara Anak agung putu ayu puspita
Published: May 2024

Daun Rhizophora mucronata dimanfaatkan masyarakat pesisir sebagai obat tradisional untuk mengobatidiare. Tujuan penelitian ini adalah mendapatkan ekstrak daun R. mucronata dan potensinya untuk dijadikansediaan obat baru yang alami, khususnya untuk mengobati diare. Metode penelitian yang dilakukanmenggunakan uji sensitivitas antibakteri dengan metode sumur agar. Ekstrak metanol daun bakau hitammemiliki rendemen tertinggi sebesar 21,47%. Komponen aktif yang terkandung dalam ekstrak metanol danair daun R. mucronata meliputi tanin, saponin, fl avonoid, fenol hidrokuinon, dan triterpenoid, sementaraalkaloid hanya terdapat pada ekstrak metanol. Ekstrak metanol memiliki aktivitas antibakteri terbesardengan zona hambat berkisar 3-12 mm. Konsentrasi hambat minimum (KHM) ekstrak metanol daun R.mucronata sebesar 0,4 mg/mL (terhadap Escherichia coli dan Pseudomonas aeruginosa), 0,2 mg/mL (terhadapStaphylococcus aureus). Bioautografi aktivitas antibakteri terhadap bakteri uji E. coli menghasilkan fraksiaktif pada nilai Rf 0,11 dan 0,72. Hasil identifi kasi dengan pereaksi Dragendorff menunjukkan senyawatersebut termasuk senyawa alkaloid.Kata kunci: antibakteri, diare, ekstrak daun R. mucronata, KHM, komponen aktif
Total neoadjuvant therapy: A new standard of care for locally advanced rectal cancer?
Authors: Leite Julio , Martins Sheila
Published: May 2024

Delivering chemotherapy before surgery is a newer treatment approach called total neoadjuvant therapy (TNT), and the National Comprehensive Cancer Network guidelines recommend it for locally advanced rectal cancer (LARC) with cT3 / cN+ / cT4, in contrast with the European Society for Medical Oncology guidelines, in which most rectal cancers can be treated with surgery alone if good quality mesorectal resection is assured. Neoadjuvant or adjuvant treatments are reserved for patients with high-risk tumours, including cT3c/d or cT4, or that threaten the mesorectal fascia. The favourable outcomes in the RAPIDO trial for high-risk rectal cancers with a lower incidence of distant metastasis in the TNT group were observed but with an unexpected increase in the local recurrence with more extended follow-up. This suggests early surgery for nonresponding tumours. The TNT approach was also evaluated in the OPRA trial with long-course chemoradiotherapy and induction versus consolidation chemotherapy. Half the patients presented complete clinical responses and were enrolled in the watch-and-wait (WW) approach. Given the high number of trials and guidelines in this subject, the multidisciplinary team's decision-making process in rectal cancer management is complex. Looking at the actual data, it was concluded that TNT is not for all patients with LARC and is an option if organ preservation is a priority, although with a high regrowth rate in a WW strategy and increasing risk of distant metastasis, questioning the deleterious effect of deferral of surgery.
An Experimental Comparison between Online and Offline Seminar for Junior Students in University—OBE-Based Perspective
Authors: Zhou Yun , Ji Yifan
Published: May 2024

Seminar is a student-led teaching mode with student-teacher interaction. The seminars for juniors are more fully infiltrated by the concept of OBE (Outcome-Based Education). After the outbreak of the COVID-19 epidemic, online teaching became widely used and entered a new stage of its own development, which both challenged and facilitated the development of traditional offline seminar courses. Our team encountered the real dilemma of Wuhan’s closure of the city in the process of offering the seminar “Social Security System Reformation in China” for juniors, and experienced an unusual process from online teaching to offline teaching. This paper hopes to explore the path of effective integration of OTO (Online to Offline) seminars by reflecting on the two rounds of OTO course experience.
The Dynamics of Triangulation in Cervantes’s El amante liberal
Authors: Collins Marsha S.
Published: May 2024

This essay analyzes Miguel de Cervantes’s El amante liberal as a type of psychomachia that dramatizes the battle between two systems of interpersonal triangulation that change and mold the conduct and character of the protagonist Ricardo, and to a degree, of the other protagonist Leonisa. René Girard’s mimetic desire, which degrades and dehumanizes individuals, and St. Thomas Aquinas’s Christian friendship, which foments love and generosity, are inscribed in the story to explore the theme of identity and offer a Cervantine paradigm of reading and interpretation. This paradigm allows for ambiguity, hybridity, and changing interpretations.
New Liberalisms for the Masses: Ontological Aristocratism and Equal Rights in José Ortega y Gasset’s La rebelión de las masas (1930) and María Zambrano’s Horizonte del liberalismo (1930)
Authors: Ryan William J.
Published: May 2024

In view of the importance of mass movements and the sociopolitical crises in the early twentieth century, this article offers close readings of the liberalisms proposed in La rebelión de las masas and Horizonte del liberalismo. Ortega posits an ontological differentiation between masas and minorías excelentes based on the notion of “effort,” allowing individuals not belonging to hereditary aristocracies to ideologically appropriate aristocratic prestige. By contrast, Zambrano emphasizes the power of reform invested in the liberal subject. Although they assess the equality of rights divergently, both philosophers coincide in situating aristocratism at the core of liberalism.
Affect and Emotions in Two Chilean Postmemory Narratives: La dimensión desconocida by Nona Fernández and La resta by Alia Trabucco Zerán
Authors: Weldt-Basson Helene C.
Published: May 2024

La dimensión desconocida (2016) by Nona Fernández and La resta (2014) by Alia Trabucco Zerán are recent novels about the memory of the Augusto Pinochet dictatorship (1973-1990) in Chile that use emotions to reconstruct a historical era through memory. The two novels share an emphasis on the affect and emotions of both readers and characters. While La dimensión desconocida is a historical novel that invites the reader to identify and empathize with the protagonists, La resta is an allegorical novel that provokes the reader to think about history by startling him or her through the narration of the protagonists' violent games.
Prototipe Lung Tumor e-mannequin untuk Pelatihan Keterampilan Fine Needle Aspiration Biopsy
Authors: Retnani Diah Prabawati , Anita Kenty Wantri , Sulistyarini Dwi Hadi , Barasabha Thareq , Nurasih Amelinda Natania , Putra Yudha Muhammad Agung , Diputra Ariyanta Dafa , Christiawan Purba Andreas Putra
Published: May 2024

Kanker paru merupakan penyebab kematian nomer 2 setelah kanker payudara dengan insiden 11,4% dari penyakit keganasan. Pengambilan spesimen untuk menegakkan diagnosis kanker paru oleh dokter spesialis Patologi Anatomik dapat dilakukan melalui prosedur Fine Needle Aspiration Biopsy (FNAB) menggunakan jarum halus melalui tuntunan imaging dari USG atau CT scan. Berbasis integrasi teknologi 3D Printer dengan manekin berbasis elektronik peneliti melakukan penelitian eksperimental dengan tujuan membuat e-mannequin yang  dilengkapi dengan tumor  paru untuk pelatihan keterampilan prosedur FNAB oleh  mahasiswa Pendidikan Dokter Spesialis Patologi Anatomik sebelum melakukan tindakan pada pasien. Pembuatan e-mannequin menggunakan bahan filamen,  tumor berbahan Thermoplastic Polyurethane (TPU) diletakkan pada  lokasi paru kiri dan kanan dengan konsistensi kenyal yang dapat dimasukkan jarum halus dan dipasang  sensor lampu sebagai validator ketepatan tindakan FNAB pada tumor paru.
A heterotopic pregnancy at 12 weeks pregnancy
Authors: Suhandri Wiwin , Riandi Diki
Published: May 2024

Heterotopic pregnancy (HP) represents a rare and complex condition where simultaneous pregnancies occur at different implantation sites, with only one located within the uterine cavity. Typically diagnosed in the first trimester, HP presents diagnostic challenges due to its rarity and varying clinical presentations. Here, we present a unique case of HP diagnosed at Bengkalis Hospital involving a 42-year-old multipara at 12 weeks of gestation. The patient's presentation included regular uterine contractions and upper abdominal pain, with a positive Plano test upon admission. Despite experiencing vaginal bleeding two days prior and an initial refusal of care, further examination revealed a 2.13 cm gestational sac in the intrauterine cavity, consistent with the gestational age. Additionally, free intra-abdominal fluid was observed in the Douglas cavity. Haematological examination indicated a low haemoglobin level of 7.2 g/dl and elevated leukocytes at 16,000. An emergency laparotomy revealed a ruptured right ovarian tube containing a gestational sac, which was managed with hemostasis and a subsequent salpingectomy. The left ovarian tube underwent a tubectomy as a preventive measure. The patient received multiple blood transfusions, leading to an improvement in haemoglobin levels to 10.2 g/dl postoperatively. Following a two-day hospitalisation, the patient was discharged in good general condition. HP cases often necessitate laparotomies for tubal pregnancies, and ultrasound plays a crucial role in diagnosis, especially given its prevalence of 1 in 7000 due to assisted reproduction. Treatment typically involves laparoscopic or laparotomic intervention, highlighting the multidisciplinary approach required for managing this rare condition.
On ideal convergence of sequences via Catalan matrix operator
Authors: Khan Vakeel Ahmad , Et Mikail , Tuba Umme
Published: May 2024

Catalan sequence initially introduced by Euler but named after Eugene Catalan has found abundant applications in the fields of probability theory, number theory, analysis, combinatorics etc. Recently İlkhan formulated the matrix associated with Catalan numbers and studied its domain in c0(C~) and c(C~). In this paper, by employing Catalan matrix defined by Catalan sequence and convergence via ideal, we establish Catalan sequence spaces c0I(C~),cI(C~) and ℓ∞I(C~), study the properties of these corresponding spaces and establish inclusion relations.
ANÁLISE IN SILICO DA BETA-CASEÍNA DE BOS TAURUS
Authors: Santos Sarah Pereira dos , Cruz Aline Helena da Silva
Published: May 2024

A Beta-caseína é uma proteína presente no leite bovino codificada pelo gene CSN2, das suas 13 variantes, entre elas A1 e A2 apresentam maior enfoque em pesquisas, pois o alelo A1 está associado ao desenvolvimento de patologias em seres humanos. A diferença entre os alelos A1 e A2 está na mutação de um par de bases que resulta na substituição de uma prolina por uma histidina. Essa mutação favorece a clivagem enzimática e ocorre a liberação do peptídeo bioativo BCM-7. A Bioinformática é a metodologia que utiliza meios computacionais para explorar e realizar experimentos científicos utilizando dados de plataformas de biotecnologia. O presente estudo utilizou ferramentas de bioinformática na análise da proteína codificada pelo gene CSN2 de Bos taurus, correlacionando proteína precursora; proteína secretada, e as variantes A1 e A2. As análises foram realizadas através da utilização de diferentes programas de bioinformática como Blastp, UniProt, Gene Runner e STRING. As análises possibilitaram a predição de peptídeos, sítios de modificações pós-traducionais e caracterização de similaridade e identidade com a Beta-caseína de outros mamíferos. Por meio do software STRING identificou-se a interação proteica da Beta-caseína com proteínas do leite. Por meio deste estudo foi possível verificar a importância e aplicabilidade da bioinformática e da internet no processamento de dados de forma mais rápida e eficiente, contribuindo para a inferência de funções de proteínas caseínas de sequência conhecida, ou mesmo preditas, a partir de sequência de gênicas disponibilizadas em bancos de dados.
INSETOS NA ALIMENTAÇÃO HUMANA: AVALIAÇÃO SENSORIAL DE BARRAS DE CEREAIS COM Tenebrio molitor Linnaeus, 1758
Authors: Macedo Ramon Marques , Neves Nataly Mendes , Sabino Rubia Marques , Pelli Afonso
Published: May 2024

Parte significativa da população global enfrenta desafios de nutrição e restrição no acesso a proteínas de origem animal. Diante desse cenário, a alimentação humana com insetos emerge como uma alternativa promissora para atender às demandas nutricionais, oferecendo uma fonte sustentável e rica em nutrientes para as populações em crescimento. Nesse contexto, esse estudo propôs testar a aceitação de barras de cereais contendo larvas do inseto Tenebrio molitor Linnaeus, 1758 por universitários em Uberaba, utilizando uma degustação em um painel sensorial como método de avaliação. Barras de cereais foram distribuídas de forma duplo cega aos universitários da Universidade Federal do Triângulo Mineiro. Após a degustação, os participantes preencheram um questionário de Perfil de Características Quantitativas, avaliando subjetivamente o Aroma, Sabor, Textura, Impressão Global e a Intenção de Compra das barras de cereais. Não foram identificadas diferenças significativas entre as barras de cereais com e sem insetos em relação ao Aroma, Sabor, Textura e Impressão Global. No entanto, foi notável um aumento significativo na intenção de compra das barras de cereais que continham a larva do Tenebrio molitor em comparação com aquelas sem a presença do inseto. Esses resultados sugerem potencial aceitação e atratividade das barras de cereais com Tenebrio molitor, indicando que pode existir uma parcela do mercado disposta a adquirir alimentos contendo insetos.
FATOR DE CONDIÇÃO DE Melanoides tuberculata (Otto Friedrich Müller, 1774), EM UM TRECHO DO BAIXO RIO GRANDE
Authors: De Paiva Luciano Henrique , Martins João Vitor Sicari , Lages Leonardo Ceccacci , Leal Álisson Borges , Lucas Bárbara Cristina Lemos , Rezende Caroline Reis RezendeCaroline Reis , Batoni Ana Giulia , Abrão Sueli Aparecida dos Santos , Pelli Afonso
Published: May 2024

Atualmente, uma das principais causas de extinção de espécies é a introdução de espécies exóticas. Melanoides tuberculata é uma espécie de molusco gastrópode tropical e subtropical de água doce, de origem africano-asiática. São prolíficas e generalistas. As populações adaptam-se bem em diversos ambientes aquáticos interiores, incluindo antrópicos. Apresentam distintos atributos, incluindo o fator de condição, que expressa a relação entre uma variável bidimensional e outra tridimensional dos organismos. O fator de condição pode ser utilizado em vários organismos diferentes, como crustáceos, moluscos, peixes, anuros ou mamíferos. O objetivo deste trabalho foi descrever a relação alométrica em Melanoides tuberculata. Foram coletados 90 indivíduos de Melanoides tuberculata. A função que melhor descreveu o fator de condição para Melanoides tuberculata foi a relação da largura das conchas de com seu volume, na função de potência.
PERLIDAE (PLECOPTERA) DO ESTADO DE SÃO PAULO, BRASIL: LISTA DE ESPÉCIES, PROBLEMAS TAXONÔMICOS E AMOSTRAGEM
Authors: Taniguti Paulo Naoto , Sarmento Felipe Ribeiro Pereira , Lopez Vinicius Marques , Kobal Renan Oliveira Alves Cardoso , Almeida Lucas Henrique de
Published: May 2024

Os plecópteros são insetos aquáticos que habitam ambientes lóticos, especialmente os de baixas e médias ordens. Por este fator, são insetos amplamente utilizados como indicadores de qualidade ambiental. De acordo com os últimos levantamentos, são conhecidas ao menos 150 espécies de Perlidae no Brasil distribuídas nos gêneros Anacroneuria Klapálek, 1909, Enderleina Jewett, 1960, Kempnyia Klapálek, 1914 e Macrogynoplax Enderleina, 1909. Apesar do bom conhecimento sobre os perlídeos brasileiros, principalmente no sudeste brasileiro, ainda são poucos os estudos que buscam organizar sistematicamente o conhecimento existente e mapear os principais problemas taxonômicos acerca do grupo. Aqui, nós apresentamos uma atualização da lista de espécies de Perlidae no Estado de São Paulo, abordando ruídos e lacunas taxonômicas e geográficas do grupo, com informações obtidas na literatura. Obtivemos uma lista totalizando 35 espécies, das quais 19, 15 e 1 pertencem respectivamente aos gêneros Anacroneuria, Kempnyia e Macrogynoplax. Das 35 espécies registradas, 10 são exclusivas do Estado de São Paulo e pelo menos 25 apresentam algum ruído ou lacuna taxonômicos, como o déficit acerca do conhecimento dos estágios de vida, com apenas 10 espécies tendo suas ninfas descritas. Finalmente, sugerimos que os futuros esforços de coleta devem se concentrar nas áreas interiores, especialmente no extremo oeste do estado.
NOVA ESPÉCIE DE Aquastroma (PLEOSPORALES, DOTHIDEOMYCETES) DE ASCOMICETOS AQUÁTICOS DAS PRAIAS ESTUARINAS DA AMAZÔNIA BRASILEIRA
Authors: Silva Carolina Ribeiro
Published: May 2024

Aquastroma aquaticum sp. nov., é um sapróbio de madeira em decomposição coletada na zona entremarés em praias fluviais da Ilha do Mosqueiro, Pará, Brasil. O táxon encontrado apresenta as principais características do gênero monotípico Aquastroma, mas difere da espécie tipo do gênero pela dimensão e morfologia do asco. Descrições morfológicas e ilustrações são apresentadas para  a espécie nova.
Acessibilidade e inclusão social no ensino superior: a importância de cursos de capacitação exercidos pelo Núcleo de Acessibilidade no interior do Amazonas
Authors: Rodrigues Cristiana Nunes , Almeida Lucas Martins , Almeida Alessandra Souza , Yamaguchi Klenicy Kazumy de Lima
Published: May 2024

O aumento de pessoas com deficiências ingressando nas escolas e universidades públicas vem crescendo ao longo dos anos. Paralelamente, as instituições de ensino superior têm buscado aperfeiçoar-se para receber tais pessoas de forma que elas possam se sentir acolhidas e importantes no convívio social educacional.  O presente artigo tem como objetivo apresentar a importância de cursos de inclusão e acessibilidade para a comunidade acadêmica e investigar as motivações da procura pelos participantes. Esta pesquisa foi elaborada com base em um curso de capacitação, oferecido pelo núcleo de acessibilidade EUAPOIO da Universidade Federal do Amazonas, Instituto de Saúde e Biotecnologia. Foi elaborado um questionário e aplicado após o curso. Como resultado, verificou-se que houve uma maior participação de graduandos do curso de licenciatura em Ciências, seguido de enfermagem. Entre as motivações, a necessidade dos conhecimentos sobre essa temática nos estágios supervisionados e a capacitação profissional foram os principais. Após o curso, os participantes sentiram-se mais preparados para lidar com situações que envolvem pessoas com deficiências, e 100% demonstraram interesse em participar de outros cursos de formação. Ainda há muitos desafios a serem enfrentados, mas o esclarecimento é uma das estratégias que oportunizam atender essa realidade, sensibilizando todo o corpo educacional e contribuindo para garantir o bem-estar físico e social de todos, de forma indiscriminada.
Jovens-estudantes do ensino médio e o uso do smartphone no mundo escolar público: práticas astuciosas, causações e tensões
Authors: Alves Guilherme Wilson Furlan Matos , Almeida Elmir de , Fonseca Sérgio César da
Published: May 2024

Este artigo apoia-se em resultados de pesquisa realizada em Programa de Pós-graduação em Educação, desenvolvida com jovens-estudantes de ensino médio de uma escola pública do interior paulista entre 2019 e 2022. Seu principal objetivo foi apreender e interpretar como a utilização do smatphone, uma  mediação cultural, por jovens-estudantes ocorria nas interações e relações que eles estabeleciam com os pares e os seus docentes–adultos no interior do mundo escolar e fora dele. De abordagem qualitativa, nas atividades de campo usou-se o levantamento bibliográfico, a observação, o registro em caderno de campo e a realização de grupos de discussão com trinta e oito (38) estudantes: dezesseis (16) do 1º ano, vinte e dois (22) do 3º ano, posicionados naquela etapa da escolarização básica. Neste texto, serão destacadas e analisadas as práticas astuciosas, as causações e as tensões que os jovens-estudantes conformaram em diferentes espaços-tempos do mundo escolar em que eles construíam interações sociais mediante o acesso e uso do smartphone.
Hepatic Expression of Genes Related to Fatty Acid Biosynthesis during Tropical Summer in Broilers: Effect of Organic Selenium Supplementation
Authors: Kantheti Jayasri , Kondeti Padmaja , Pagadala Eswara Prasad , Kaliki Adilaxmamma , Ravi Arunachalam , Bhupati Punyakumari , Kumar A.V. Siva
Published: May 2024

Background: The physiological responses during adaptation to summer in poultry could be related to modulation of energy metabolism. Enhanced deposition of fat in spite of reduced feed intake seems to have an advantage under hot conditions. Thus, the present study was conducted to investigate the seasonal status of de novo synthesis of fatty acids in broiler chicken (Gallus gallus) and its response to organic selenium supplementation. Methods: The study was conducted in two phases, one during autumn and the other during summer, with a total of 300 birds as autumn control, summer control, group-I (0.3 ppm SeMet), group-II (0.6 ppm SeMet) and group-III (0.9 ppm SeMet) groups. Blood samples and hepatic tissues were collected at 21 and 42 d for further analysis. Result: An elevation in serum lipid profile, glucose, cortisol and T4 levels was observed during the summer while the T3 concentration decreased compared to the autumn. The hepatic expression of Acetyl Co. A carboxylase α (ACCα) and Fatty acid synthase (FASN) was increased at 21 d, while it was decreased at 42 d during summer in broilers. Serum total cholesterol levels and LDL levels decreased with SeMet at 0.6 and 0.9 ppm levels. The expression of hepatic ACCá and FASN genes was decreased with selenium supplementation at higher levels. Increased serum total cholesterol levels were associated with lower de novo fatty acid synthesis at 42d during summer in broilers.
Beyond Functionality: Morphological Design Tools for Users’ Satisfaction in Housing
Authors: Bulut Halise Betül , Akbar Jamel
Published: May 2024

Various factors can affect an individual’s satisfaction level. While studying residential satisfaction and assessing it, subjective perceptions have the most significant influence. An essential element in ensuring satisfaction in housing is to consider the design of spaces that cater to individuals’ specific desires and needs that change over time.
Housing was frequently constructed considering the specific subjective needs of individuals, before the era of industrialization. As industrialization rises, housing gradually transformed into a commodity. Certain researchers propose that studying traditional built environments and harnessing the data gained from such analyses can be advantageous for contemporary housing production. Notably, Habraken is a prominent researcher who sought to ensure users’ satisfaction in housing by devising the “Support System” rooted in his analysis of Dutch houses. Traditional house plans in Türkiye exhibit resemblances to the morphological arrangements observed by Habraken in Dutch houses, yet with some distinctive characteristics.
In modern times, designers often prioritize function as the primary consideration. However, there have been attempts, such as Habraken’s, to shift towards prioritizing morphology instead. This paper will explain links between users’ satisfaction and their ability to change their immediate environments through morphologies that accommodate diverse functions.
OPTIMALISASI PEMILIHAN RUTE DAN MODA PADA PROSES DISTRIBUSI PRODUK YANG KAITANNYA DENGAN BIAYA LOGISTIK
Authors: Rafi Muhammad , Angkat Futri Okana , Alethea Gress , Dwipayana Arif Devi
Published: May 2024

Agriculture is sector Which source nature for various human needs. Jatiluwih is red rice planting and production area in the Province of Bali. Distribution is the activity of distributing products from producers to consumers. The purpose this study is determine the routes and modes used transport red rice from five regions to Denpasar with more economical logistics costs using the Saving Matrix method and the QGIS Application, because the previous goods distribution channel was less effective and resulted in large logistics costs. So this research is useful for brown rice business actors in the Jatiluwih Region to distribute their processed products. After method saving matrix and the use of the QGIS application was successful in processing data, it can be concluded that this method resulted savings in terms of routes, time and logistics costs incurred in the goods distribution process carried out by business actors in the Jatiluwih Area.
ABSTRAK
Pertanian merupakan sektor yang digunakan sumber daya alamnya untuk berbagai keperluan manusia. Jatiluwih merupakan kawasan penanaman dan produksi beras merah yang terkenal di Provinsi Bali. Distribusi adalah aktivitas menyalurkan produk dari produsen sampai ke tangan konsumen. Tujuan dari penelitian ini yaitu menentukan rute dan moda yang digunakan untuk mengangkut beras merah dari lima Kawasan ke Denpasar dengan biaya logistik yang lebih hemat menggunakan metode Saving Matrix dan Aplikasi QGIS, dikarenakan jalur distribusi barang sebelumnya kurang efektif dan menimbulkan biaya logistik yang besar. Sehingga penelitian ini bermanfaat bagi pelaku usaha beras merah di Kawasan Jatiluwih untuk mendistribusikan produk olahannya. Setelah metode saving matrix dan penggunaan aplikasi QGIS berhasil dijalankan dalam mengolah data, maka dapat disimpulkan bahwa cara tersebut menghasilkan  penghematan dari segi  rute, waktu dan biaya logistik yang ditimbulkan dalam proses distribusi barang yang dilakukan oleh pelaku usaha di  Kawasan Jatiluwih.
Flowering Plants and Ferns of North Garhwal, Uttar Pradesh, India
Authors: Rau M. A.
Published: May 2024

The paper gives an account of the recent collection of flowering plants and ferns from the Garhwal Himalayas, made by the author during the years 1957 to 1959 in which nearly 1500 gatherings were made which on study yielded 738 species. The area covered by this study lies between 30Â° and 31Â° N., and 79Â° and 80Â° E., and includes the Alaknanda, Arwa, Bhyundar, Khiraun, Mandakini and Nandakini river valleys and their neighbouring glacial beds, mountain slopes and meadows ranging in altitude between 2000 and 4500 metres. Cypripedium elegans Reichb. f., a rare terrestrial orchid was collected for the first time in Western Himalayas.
The Genus Nechamandra in India
Authors: Subramanyam K. , Balakrishnan N. P.
Published: May 2024

In all Indian floras Necharnandra alternifolia, a common aquatic herb of Hydrocharitaceae, is described under the genus Lagarosiphon. Some authors use the name Lagarosiphon roxburghii; others place it under Lagorosiphon alternifolia. The correct name of this plant is Nechamandra alternifolia (Roxb.) Thw. This note presents complete synonymy, detailed description and distribution in India.
Notes on Systematics, Cytology and Culture of Paphiopedilum venustum (Lindl.) Pfitz.
Authors: Kataki S. K.
Published: May 2024

This paper presents a short note on systematics and cytology on Paphiopedilum venustum (Lindl.) Pfitz. (= Cypripedium venustum Lindl.) where the chromosomes are found to be 2n = 40 in the tapetal cells. The cultural notes are also given based on the observation made on the plants growing in the National Orchidarium, Shillong.
Melanoma of the Nail Unit
Authors: Catizani Lopes Laís , Castro Guimarães Mariana , Pimenta Marques Joana , Lencastre André
Published: May 2024

N/a.
MUJTAHID, AKHBARI DAN USHULI METODE ISTINBATH HUKUM DALAM TRADISI MAZHAB SYI’AH
Authors: Musawar Musawar , Zuhdi Muhammad Harfin
Published: May 2024

Otoritas keagamaan dalam tradisi mazhab Syi’ah diyakini beradadi tangan para imam. Dengan atribut kemaksumannya, imam diklaimmemiliki otoritas sebagai penafsir firman Allah. Setelah era para imamberlalu, maka estafeta kepemimpinan berada di pundak para ulama. Atasdasar inilah segala urusan berkaitan dengan pemerintahan dan keagamaanberada di tangan seorang atau sejumlah faqih yang tergabung dalam instutusiwilayat al-faqih. etting sosial munculnya marja’ al-taqlid ditengarai olehperbedaan dua faksi dalam dalam mazhab syi’ah, Akhbari dan Ushuli. Akhbaridiindentifikasi sebagaikelompok tekstualis dan skripturalis yang menolakprinsip-prinsip rasional dalam memahami nash al-Qur’an dan Sunnah. Merekamenolak metode qiyas, ijtihad dan khabar wahid. Sedangkan Ushuli adalahkelompok yang mengakomodir prinsip rasional dalam memahami nash danmenyimpulkan hukum-hukum berbasis ijtihad (penalaran sungguh-sungguhberdasarkan syariat) bagi yang memiliki kompetensi dan memenuhi berbagaipersyaratan kualifikasi untuk itu. Namun bagi mereka yang tidak memilikikualifikasi ijtihad diwajibkan untuk mengikuti para mujtahid. Proses inilahyang disebut sebagai taqlid dan ulama yang mempraktikkan ijtihad yangdipilih untuk diikuti disebut sebagai marja’al-taqlid.
An intellectual property analysis: advances and commercialization of low-dimensional carbon materials in batteries
Authors: Su Chang , Gao Xuan , Liu Kejiang , Wang Shudi , Dai Yuhang , Dong Haobo , Liu Yiyang , Zhu Jiayan , Zhang Qiuxia , He Guanjie
Published: May 2024

There is a growing demand for energy consumption in society due to the increasing application of emerging technologies. Therefore, the need for the development of advanced energy storage technologies to cope with the rising energy demand is rising. Carbon materials play significant roles in energy storage technologies. In this review, the research progress and applications of low-dimensional carbon materials in batteries, including carbon quantum dots, carbon nanotubes, and graphene, are summarized. The performance of these materials is compared against traditional lithium-ion batteries with graphite, which has limitations in its bandgap and reversible capacity. A mini-intellectual property analysis and the advances and commercialization of low-dimensional carbon materials in batteries were provided. The challenges and limitations associated with using these materials as electrode materials were discussed, and a market overview of their commercialization was provided. Finally, future directions for research and development in this field were concluded. Overall, this review provides a comprehensive overview of low-dimensional carbon materials as a promising research area for developing advanced batteries to meet the growing demand for energy consumption.
To what extent can a phase-out of pesticides in viticulture be achieved? Learning from the efforts of a large farm network after 10 years
Authors: Nefti Olivier , Chartier Nicolas , Merot Anne , Peyrard Thibault , Delière Laurent
Published: May 2024

In accordance with European Directive 2009/128/CE, France has set up national policies to curb the reliance of agriculture on phytosanitary inputs. The DEPHY network is one such initiative;, which has been designed to drive, support and document the fieldwork of 3,000 farms voluntarily taking part in a collective input reduction programme. This study aimed to describe the achievements of the network’s viticultural sector, as its perennial crop is heavily reliant on pesticide applications. We chose a sample of 343 wine-growing systems across mainland France,  analysed records of their vineyard operations from before they joined the network, and compared them to those from the 2017-2020 period. We used the Treatment Frequency Index (TFI) to assess pesticide reliance together with other techno-economical parameters: production costs, workloads, greenhouse gas emissions and disease control. A significant decrease in pesticide use was found over the whole study period, with, for instance, an average TFI reduction of 24 %, which is consistent with national objectives but unmatched outside of the network. We observed an overall shift towards pesticide inputs with lower repercussions on health or the environment, as well as different TFI reduction trajectories based on initial pesticide dependency. We described the alternative practices introduced to the systems, and our results suggest that reductions in pesticide use stem from quite small and minor changes made to the cropping systems. These new practices only slightly lowered the vineyards’ technical and economical performances in specific situations involving an indepth revamping of the systems; e.g., conversion to organic viticulture. To increase pesticide phase-out, further research is needed on redesigning cropping systems, and on how to scale up the network’s results to the national level.
Evaluating Performance of the US Surveillance Systems for Monitoring Antimicrobial-Resistant Gonorrhea: An Agent-Based Modelling Study
Authors: Prakhova Sofya
Published: May 2024

In this study we evaluate performance of two American surveillance systems for monitoring the spread of antimicrobial-resistant (AMR) gonorrhea: the Gonococcal Isolate Surveillance Project (GISP) and the enhanced Gonococcal Isolate Surveillance Project (eGISP) which includes the non-urethral isolates in addition to the urethral ones utilized in the original surveillance system. A continuous-time agent-based model of gonorrhea transmission among the US men who have sex with men (MSM) population was developed and used for this purpose. Our results show that the accuracy of eGISP was nearly 10% higher than the accuracy of GISP (97.8% (95% uncertainty interval: 83.5%, 100%) vs. 87.9% (55%, 100%)). Most of time, GISP detects the moment when the resistance to the first-line antibiotic reaches the switch threshold recommended by the WHO later than when it was actually reached. This leads to the additional spread of AMR gonorrhea. We also found that including the extragenital isolates in the surveillance is more important for the accurate monitoring than increasing the number of isolates. Finally, our results demonstrate that rectum and pharynx can serve as a niche for fostering antimicrobial resistance. These findings provide a scientific basis which can be used to inform the decision made by the policymakers on how many GISP and eGISP sites to establish each year.
The Fine Thread between Stability and Randomness of the Non-stationary D/M/1 Queue’s GI/M/1 Pointwise of Stationary Fluid Flow Approximation Model with Application Ultra-Low Latency of Autonomous Driving Service
Authors: A Mageed Ismail , Becheroul Amina
Published: May 2024

The current work reveals the fine tuning between stability zones and randomness of GI/M/1 Pointwise Stationary Fluid Flow Approximation (PSFFA) model of the non-stationary D/M/1 queueing system. More specifically, this clearly provides more insights into developing a contemporary PSFFA theory that unifies non-stationary queueing theory with chaos theory and fields in both theoretical physics and chaotic systems. This opens new grounds for stability analysis of non-stationary queueing systems. A notable application of GI/M/1 queueing model to achieve ultra-low latency of autonomous driving service is highlighted. Concluding remarks associated with future avenues of research are given.
Cognitive Strategy Instruction in Vocabulary Learning Task: the Role of Intelligence
Authors: Izmalkova Anna
Published: May 2024

In paired-associate vocabulary learning task, second language learners employ different cognitive strategies, associated with either elaborative or rote rehearsal, resulting in different recall performance. The current study investigated the role of intelligence, measured with Raven’s Advanced Progressive Matrices, in strategy effects on performance and eye movement parameters. The Keyword method, which is regarded as a more effective cognitive strategy in paired-associate task, was induced on a sample of 32 healthy participants with normal or corrected to normal vision. Effective cognitive strategy use, mentioned in a structured post-hoc report, was found to improve performance after strategy induction. Higher intelligence score was associated with higher recall performance in case the Keyword method was reported, but not in the cases when no rote rehearsal was reported. No effect of cognitive strategy use on eye movement measures after explicit cognitive strategy instruction was revealed, which is supposed to be connected with lack of self-sustained strategy use immediately after strategy instruction. The findings emphasize the role of intelligence in cognitive strategy instruction.
Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population
Authors: Maeso Mendez Sandra , Gago Martin Ruth , Jauregui Benito Eider , Costa Serra Laura , Gainzarain Serna Andrea , Prigent Diaz Annabel , Sola Sarabia Carlos , Ogueta Lana Mikel , Diez Lopez Ignacio
Published: May 2024

Introduction: Type 1 diabetes mellitus is a chronic disease of autoimmune etiology that is highly prevalent in childhood. In the last decade, the possibility of using the Bacillus Calmette-Guérin vaccine for the treatment of this disease has been studied thanks to its immunomodulatory action .
Objectives: The objective of this work is to carry out a systematic review of the available scientific evidence on the relationship between the tuberculosis vaccine and the treatment of diabetes in childhood. Secondarily, the aim is to study the incidence of Type 1 Diabetes Mellitus in a cohort of children from the Basque Country according to whether or not they have received the vaccine.
Methods: An exhaustive bibliographic search has been carried out on the evidence available to date. For the epidemiological study in Euskadi, a comparison of accumulated incidences between vaccinated and unvaccinated population groups was made.
Results: According to the literature analyzed, There is more and more evidence about the possible use of the tuberculosis vaccine in Type 1 Diabetes Mellitus. The results of our study were not conclusive, but we believe that it is necessary to continue with long-term studies to eliminate biases.
Conclusions: The Bacillus Calmette-Guérin vaccine could be used for the treatment of autoimmune, allergic, infectious or oncological processes, although more studies are still necessary in this regard.
Digital Transformation, Absorptive Capacity and Enterprise Esg Performance: A Case Study of Strategic Emerging Industries
Authors: Li Wenjun , Zhang Mu
Published: May 2024

Digital transformation provides new drivers for economic performance growth in enterprises, but can it further improve ESG performance and support sustainable development? Based on the perspective of resources and capabilities, this paper uses the relevant data of 1588 listed companies in strategic emerging industries from 2011 to 2021 to study the differential impact of digital transformation on enterprise ESG performance, and further tests the mediating role of absorptive capacity and the moderating role of regional digital level. The research results indicate that: firstly, digital transformation of enterprises can positively promote the improvement of ESG performance; Secondly, there are significant differences in the impact of digital transformation on the ESG performance of enterprises in terms of property rights and industry characteristics. The ESG performance of state-owned enterprises and high-end equipment manufacturing enterprises is more sensitive to digital transformation; Thirdly, absorptive capacity plays a mediating role between digital transformation and corporate ESG performance; Fourthly, the positive regulation of regional digital level promotes the ESG performance of enterprises through digital transformation. The research conclusion is based on a digital perspective, providing relevant insights for improving the ESG performance of strategic emerging industry enterprises and expanding their ESG development paths.
A Qualitative Investigation of Parent Perceptions of Home Exercises for Congenital Muscular Torticollis
Authors: Stitt Audrey , Operacz Rebecca
Published: May 2024

The purpose of this qualitative study was to describe parent perceptions of the home exercise pro-gram (HEP) for their infant with congenital muscular torticollis (CMT), and how these perceptions evolved over a physical therapy (PT) plan of care. Twelve participants were recruited from a pediatric PT clinic, and nine completed interviews at three time points. Qualitative description and an iterative approach for thematic analysis of 27 interviews yielded three themes that corresponded to the research questions. The participants’ responses were categorized into three main themes: 1) parents’ perceptions of three key exercises within the HEP; 2) internal and external sources of stress; and 3) sources of empowerment and disempowerment. Regarding the HEP, parents articulated common sentiments for three frequently prescribed exercises for the management of CMT: 1) Tummy time was the fast favorite, 2) ipsilateral cervical rotation was perceived as stressful, and 3) contralateral cervical lateral flexion felt uncomfortable. Additionally, participants disclosed internal and external sources of stress (guilt, uncertainty, and the demands of returning to work) and sources of disempowerment (inconsistent messaging from providers, feeling overwhelmed) and empowerment (being able to see the bigger picture and clear communication and education about the diagnosis) with respect to managing their infant’s CMT. These themes provide insight into the evolution of parent perceptions over a PT plan of care for CMT. Participants’ insights suggest a need for consistent messaging regarding the diagnosis and evidence-based management of CMT, addressing parent stress, and modifying how exercises are taught. This study contributes updated research on parents’ experience with physical therapy and the HEP for their infant’s CMT.
Energy Metabolism Pathways in Stem Cell Fate Regulation
Authors: Wang Mingyue , Yang Xiaoguang , Cao Hongguo
Published: May 2024

Energy metabolism regulates the proliferation of stem cells by regulating energy production and the production of substrates through biosynthetic pathways. It is an important target for cell regulation and stem cell applications, and is crucial for determining the pluripotency and cell fate of stem cells. In this context, this article focuses on reviewing the latest research progress on the association between glucose metabolism, amino acid metabolism, fatty acid metabolism, and mitophagy with stem cell function, elucidating how key energy metabolism pathways affect stem cell function by regulating signal transduction and epigenetic modifications. In this review, we discuss the key factors affecting energy metabolism and their association with stem cell function. The integration of energy metabolism and stem cell fate regulation will open up a new path for future regenerative medicine practices.
Sustainable Sensing with Paper Microfluidics: Applications in Health, Environment, and Food Safety
Authors: Kumar Sanjay , Kaushal Jyoti Bala , Lee Heow Pueh
Published: May 2024

This manuscript offers a concise overview of paper microfluidics, emphasizing its sustainable sensing applications in healthcare, environmental monitoring, and food safety. Researchers have developed innovative sensing platforms for detecting pathogens, pollutants, and contaminants by leveraging the paper’s unique properties, such as biodegradability and affordability. These portable, low-cost sensors facilitate rapid diagnostics and on-site analysis, making them invaluable tools for resource-limited settings. The review discusses fabrication techniques, principles, and applications of paper microfluidics, showcasing its potential to address pressing challenges and enhance human health and environmental sustainability.
Brake Wear and Airborne Particle Mass Emissions from Passenger Car Brakes in Dynamometer Experiments based on Worldwide Harmonized Light-Duty Vehicles Test Procedure Brake Cycle
Authors: Hagino Hiroyuki
Published: May 2024

Brake wear particles, as the major component of non-exhaust particulate matter, are known to have different emissions, depending on the type of brake assembly and the specifications of the vehicle. In this study, brake wear and wear particle mass emissions were measured under realistic vehicle driving and full friction braking conditions using current commercial genuine brake assemblies. Although there were no significant differences in either PM10 or PM2.5 emissions between the different cooling air flow rates, brake wear decreased and ultrafine particle (PM0.12) emissions increased with increasing cooling air flow rate. Particle mass measurements were collected on filter media, allowing chemical composition analysis to identify the source of brake wear particle mass emissions. The iron concentration in the brake wear particles indicated that the main contribution was derived from disc wear. Using a systematic approach that measured brake wear and wear particle emissions, this study was able to characterize correlations with elemental compositions in brake friction materials, adding to our understanding of the mechanical phenomena of brake wear and wear particle emissions.
In Vitro Hemostatic Activity of Novel Fish Gelatin- Alginate Sponge (FGAS) Prototype
Authors: Herliana Heri , Yusuf Harmas Yazid , Laviana Avi , Wandawa Ganesha , Abbas Basril
Published: May 2024

A hemostatic sponge prototype was successfully synthesized from fish gelatin as an alternative to mammalian gelatin, which was mixed with alginate in certain combinations and double cross-linking of calcium ions and gamma irradiation at a dose of 20 kGy to improve the characteristics and effectiveness of its function as a local hemostatic agent. There was an improvement in the physicochemical and mechanical properties, porosity index, absorption capacity, biodegradation properties, biocompatibility, and hemocompatibility of the FGAS prototypes compared with the pure fish gelatin sponge. Hemostatic activity tests showed that the means of clotting time, prothrombin time, and activated partial thromboplastin time were shorter in the FGAS prototype than in the negative control, and there was no significant difference compared with the commercial gelatin sponge. The hemostatic mechanism of the FGAS prototype combined a passive mechanism as a concentrator factor and an active mechanism through the release of calcium ions as a coagulation factor in the coagulation cascade process.