bluuebunny/crossref_metadata_2025 huggingface dataset:
Sahih Kırâatlerin Tespit Kriterlerinde Gelişme ve Genişleme
Authors: Uzun Yakup
Published: June 2023

Kur’ân-ı Kerîm, edebiyatın ve belâgatın zirve olduğu bir dönemde inmiştir. O günlere tanık olan insanlar, Kur’ân’ın sûre ve âyetlerinin eşsiz nazmı ve güzelliği karşısında aciz kalmışlar, edipler ve muallaka şairleri bile hayranlıklarını dile getirmekten kendilerini alamamışlardır. Bu eşsiz eser, Hz. Peygamber (s.a.s.) vesilesiyle hem okunmuş hem okutulmuş hem de vahiy kâtipleri vasıtasıyla kayıt altına alınarak kuşaktan kuşağa aktarılmak suretiyle bizlere ulaşmıştır. Bu kuşakların en önemli halkalarını ashâb-ı kirâm, tâbiîn ve etbâu’t-tâbiîn dönemleri oluşturmuştur. Özellikle bu kuşaklardan sahâbe, Hz. Peygamber’den işittiği ve öğrendiği kırâatleri şifahi hem de yazılı olarak aktarmada ilk halkayı teşkil etmişlerdir. Öyle ki bunlar, bizzat Hz. Peygamberden öğrendikleri kırâatleri bu şekilde aktarmanın yanı sıra Kur’ân kırâatlerine göre imlâ ve istinsah etmiş, arza-i ahîreye uygun kırâatleri iki şahit şartı ile titizlikle kaydetmişlerdir. Bu uygulamadan sonra kırâatlerin tespit kriterleri temayüz etmeye başlamış, bu kriterlerden isnat ve Mushaf imlâsı konusunda Müslümanlar arasında pek ihtilaf oluşmamasına karşın; icma, tevatür şartı gibi kriterler üzerinde birtakım farklı görüş ve yorumlar zuhur etmiştir. Arap olmayanların İslâm’a girmesiyle birlikte dildeki lahnın (hatanın) yaygınlaşması bariz bir şekilde görülür olmuştur. Bu da Kur’ân’ın doğru okunabilmesi için Arapça gramerine uygunluk, harekeleme vb. birtakım çalışmaların yapılmasını gündeme getirmiştir. Söz konusu çalışmalar ise sonraki dönemlerde belirlenen kırâatlerin sıhhat kriterlerini çeşitlendirerek ziyadeleştirmiştir. Bu bağlamda söz konusu çalışmayla kırâat ilminin tanımı kısa bir şekilde verilmiş, ardından sahih kırâatlerin tespit kriterleri Hz. Peygamber döneminden başlatılmak suretiyle sahâbe, tâbiîn ve tedvîn dönemlerini kapsayacak şekilde araştırılmış, bu kriterlerde gelişme ve genişleme olup olmadığı ortaya konmuştur. Neticede Hz. Peygamber ile başlayan bu uygulama, sahâbe ve tâbiîn dönemlerinde merhale merhale gelişip genişleyerek tedvîn dönemine girildiği görülmüş, tedvîn döneminde ise tekâmül noktasına ulaştığı anlaşılmıştır.
Provocaciones sentipensadas desde Colombia para cuestionar el ‘enfoque diferencial’
Authors: Munévar Munévar Dora Inés , Torres Rodríguez Nicolás , Martínez Sánchez Ángela Patricia
Published: June 2023

El presente artículo tiene dos objetivos fundamentales: cuestionar el discurso institucional del ‘enfoque diferencial’ y a las formas que este ha tomado en el campo de las políticas públicas en Colombia; y plantear alternativas que permitan repensar y resentir otros panoramas para dicho campo, especialmente desde perspectivas interseccionales. En el texto se explora de manera crítica cómo y por qué esta estrategia particular de gestión de la diferencia reproduce binarismos y esencialismos espurios y, sobre esa base, exponemos sus maneras de producir cercos en la esfera institucional. Finalmente, presentamos algunas reflexiones en favor de alternativas interseccionales sobre las que, consideramos, se pueden establecer agendas públicas mucho más plurales y expansivas en Colombia.
¿Interculturalidad o ‘cultura’ a lo occidental? El rechazo indígena hacia la educación intercultural bilingüe
Authors: Tym Christian
Published: June 2023

A pesar de ser un principio constitucional, la interculturalidad se encuentra en crisis en Ecuador. Un síntoma de esta crisis es el rechazo o indiferencia hacia la educación intercultural bilingüe (EIB) por parte de varios pueblos indígenas. A través de un estudio de caso de esta actitud por parte del pueblo shuar que reside en la provincia Zamora Chinchipe, Ecuador, propongo que esta tiene sus orígenes en las políticas eurocéntricas de interculturalidad, en las que presumen en qué consiste la diferencia cultural y a qué aspira la familia indígena en cuanto educación, desatendiendo la lucha para la movilidad social en contextos de desigualdad material como parte central de las culturas actuales. Concluyo que resulta indispensable llevar a cabo una descentralización de las políticas públicas para lograr una verdadera interculturalización del Estado desde las experiencias contemporáneas y a partir de las necesidades reales de las comunidades indígenas.
Cambio de identidad y uso de Facebook en adolescentes y jóvenes indígenas de la Sierra central ecuatoriana
Authors: Waters William F. , Baca Martin , Tipanquiza Shirley , McGrath Emily
Published: June 2023

El uso de las redes sociales brinda nuevas oportunidades para expresar nuestra identidad al mundo. La presentación de las personas en las plataformas de internet está extendida incluso entre los adolescentes y jóvenes indígenas que viven en comunidades rurales de la Sierra ecuatoriana. Sus representaciones informan no solo sobre su autodefinición, sino también sobre las aspiraciones futuras. Para las comunidades caracterizadas por la pobreza y la agricultura de pequeña escala, el acceso a internet les permite aprovechar las redes sociales y así mostrar su propia identidad al mundo a través de imágenes fotográficas en Facebook. A través de un análisis de contenido de las imágenes de los perfiles de Facebook y entrevistas cara a cara se realizó un estudio de cómo las representaciones de identidad reveladas en las fotografías de perfil de dicha red social se relacionan con la educación, la ocupación actual y las proyecciones para el futuro de adolescentes y jóvenes indígenas de la parroquia de Guangaje, Ecuador. Se encontró que si bien las representaciones de la identidad difieren según el género, reflejan aspiraciones de educación superior y ocupaciones profesionales o técnicas no agrícolas, lo cual representa un desafío para la política pública.
Catalepsy test (Bar test) v1
Authors: Chen Chuyu
Published: June 2023

The catalepsy test (bar test) was developed to test motor coordination and motor impairments.
Sectioning of Mouse Brain by Cryostat v1
Authors: not provided maryana.nissan
Published: June 2023

This protocol describes how to use the cryostat to prepare and slice mouse brain sections for Immunohistochemistry
Systematic review of user experience and trust improvement evaluations on healthcare oriented explainable artificial intelligence v1
Authors: Soto-Rey Iñaki
Published: June 2023

Many different AI systems have been developed in recent years. The field of explainable AI is designed to shed light on the black box modles of the various AIs. However, the explainable AI is rarely developed in relation to the needs of the users, but is based on the technical side that the AI structure provides. Our goal is to explore the various scientific researches that have been conducted on explainable AI in terms of user satisfaction. This goal is to be achieved through a systematic review based on the PRISMA guidelines.
Cidades Inteligentes sob a ótica da Motivação Humana: um constructo baseado nas Necessidades de Maslow.
Authors: Andrade Murilo Fonseca , Coutinho Mauro Margalho , Mendonça Junior João Paulo Vasconcelos
Published: June 2023

As Cidades Inteligentes objetiva melhorar a vida urbana, tornando-as cidades mais eficientes, ecológicas, inclusivas e com maior qualidade de vida para todos os cidadãos. A aplicação da teoria de Maslow no planejamento urbano pode atender às necessidades fundamentais dos cidadãos A relação entre as necessidades de Maslow e a construção das Cidades Inteligentes é um tema interessante que tem sido explorado em alguns estudos. Embora a teoria de Maslow não tenha sido especificamente formulada com foco nas Cidades Inteligentes, é possível fazer algumas conexões e extrair insights relevantes. Neste sentido, busca-se encontrar trabalhos associados a Cidades Inteligentes e as Necessidades de Maslow e suas relações e contribuições para a construção das Cidades Inteligentes. Foi realizado uma pequena revisão sistemática da literatura para reunir e analisar de forma sistemática e imparcial os documentos científicos disponíveis sobre as Cidades Inteligentes e as Necessidades de Maslow. Os estudos que exploram a relação entre as necessidades de Maslow e as Cidades Inteligentes podem abordar diferentes aspectos, como a análise das necessidades específicas dos cidadãos em diferentes níveis da pirâmide de Maslow em contextos urbanos inteligentes, a identificação de como as cidades inteligentes podem melhorar a satisfação das necessidades humanas, ou mesmo o desenvolvimento.
Emlékezés Isépy István flóra- és vegetációkutatóra (1942-2022)
Authors: Csontos Péter , Kalapos Tibor , Orlóci László , Papp László
Published: June 2023

Isépy István (1942-2022), magyar botanikus, flóra- és vegetációkutatóra emlékezünk. Már fiatal korától a növényvilág megismerése érdekelte, ezért a gimnázium elvégzése után az ELTE biológia-kémia tanári szakára jelentkezett, ahol 1966-ban szerzett diplomát. Az egyetem elvégzése után az ELTE Botanikus Kertben működő MTA kutatócsoportban kapott állást, majd 1982-től 2005-ig, nyugdíjazásáig az ELTE Füvészkert igazgatójaként dolgozott. Kutatómunkája során vizsgálta a Vértes hegység erdőtársulásait, a gyertyános-tölgyesek anyagforgalmát, a Pannonicum szárazgyepeit és a védett növényfajok ex situ megőrzésének és szaporításának lehetőségeit. Emellett részt vett a flóra- és vegetációtérképezés országos mozgalmában, valamint aktív szerepe volt természetvédelmi területek létrehozásában. Mint egyetemi oktató elsősorban növényrendszertant és biogeográfiát oktatott. Emellett népszerűek voltak a hallgatóság körében a szorgalmi időszakban tartott botanikus kerti növényismeret, illetve magashegységek növényvilága speciális kollégiumai, valamint a nyári vakáció idejére szervezett, fakultatív részvételű, magashegységi terepgyakorlatai. Botanikai expedíciókat és hallgatói terepgyakorlatokat vezetett Üzbegisztánba, Grúziába, Ausztriába, Szlovéniába, Olaszországba és Erdélybe. Munkásságáért több elismerésben részesült, többek között a Magyar Érdemrend lovagkeresztje polgári tagozata kitüntetést is elnyerte, a Magyar Biológia Társaság pedig sokoldalú tevékenységéért, de különösen a kiemelkedően hosszú lapszerkesztői munkájáért Gelei József életműdíjban részesítette. A botanika tudományáért és annak népszerűsítéséért tenni akaró, kedves és segítőkész személye mindig hiányozni fog. Emlékét méltón őrizzük a hazai botanikusok és az ELTE Füvészkert vezetőinek panteonjában.
Problem laboratory of physical and chemical research of rocks of Taras Shevchenko National University of Kyiv. 50 years of university science
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Shabatura O.
Published: June 2023

The formation of the Problem laboratory of physical and chemical research of rocks of the Geological faculty (Institute of Geology) of Taras Shevchenko National University of Kyiv is closely related to the development of the geological branch of Ukraine. Many years of geochemical and petrophysical research on numerous and diverse geological objects laid the foundation for the formation of the scientific school "Applied petrogeochemistry and petrophysics of igneous rocks", under the leadership of prof. M.I.Tolstoy. The short article provides the main development milestones, the scientific and applied phasing of the Problem Laboratory, as well as an incomplete list of the achievements of the laboratory's employees and people related to it.
On the 111th CAA Annual Conference of the Art Historians
Authors:   The Ethnology Institute UNAS (Lviv, Ukraine), Levytska Mariana
Published: June 2023

The review is dedicated to covering the program and topics of the Annual scientific conference of the College Art Association (САА), which took place in New York in February 2023. This conference is one of the most important scientific events in the fields of academic art history, history and theory of design, visual culture studies, museology, and curatorial practices. The program of the 2023 conference demonstrated that art historians strive to expand methodological approaches and build research in intermedial and transcultural perspectives, while artists and designers aim to meet the current challenges of the epoch and the needs of society.
Empowerment Respect: A Conception of Respect Suitable for People with Severe and Profound Intellectual Disabilities
Authors: O'Connor Cara
Published: June 2023

No abstract available.
Disability Identity in Older Age? - Exploring Social Processes that Influence Disability Identification with Ageing
Authors: Leahy Ann
Published: June 2023

While there is much debate about a disability identity, this does not apply to the identification processes of people experiencing impairment or disability first in older age, who are often assumed not to identify with a disability identity. This article aims to deepen understanding of the elements affecting identification with disability when impairment is experienced first in older age and their interplay. It does so by discussing findings from a new empirical study drawing on data from interviews with people first experiencing impairment with ageing and by engaging with scholarship from both critical studies on ageing and on disability. The findings discussed show that the issue of a disability identity in older age is more complex and fluid than has heretofore been assumed and that identity is always subject to renegotiation. It points to the role of dominant and binary discourses of ageing, and separate policy frameworks and approaches to activism on ageing and on disability, in constructing (or failing to construct) a ‘disability’ identity in older age. The article argues for greater linkages between the fields of ageing and disability in scholarship and advocacy and suggests that this offers potential to make the issue of ableism more broadly understood and resisted. It calls for more engagement by disability scholars with what disability experienced in older age illuminates about culture and with the implications of disability becoming a more widespread phenomenon due to population ageing.
Patient Resistance to Psychiatric Discourse and Power
Authors: Johnston Matthew S. , Sanscartier Matthew D. , Steckle Rhys
Published: June 2023

Drawing on 5090 English reviews of 486 psychiatrists working in Canada posted on ratemds.com, this study explores how mental health service users refuse to become subjectivized by psychiatric discourse and power. We interrogate how digital mediums provide mental health service users with a community of critique to regain control over settings where there are many power imbalances. We argue that websites like ratemds.com act as a digital agora in which people are afforded the ability to make the personal political. Through critiquing their own doctors, mental health service users invert the question of what is “wrong” with them to what is “wrong” with agents of the psychiatric apparatus. By regaining a say over their treatment/conditions and insisting doctors are asking the wrong questions to better control their identities, service users refuse to accept the diagnoses, pathologies, and practices imposed on them. We discuss how their transgression in this forum provides new insights into psychiatric resistance that is of special interest to scholars and service users positioned in the Mad Studies movement.
“Checking a Box Isn’t Exactly Helpful”: Interpretations of the Voluntary Self-Identification of Disability Form During the Job Application Process
Authors: Duncan Kaylin , Sias Patricia M.
Published: June 2023

The United States Department of Labor created the Voluntary Self-Identification of Disability (VSD) form in 2014 to improve the employment rate for people with disabilities. As part of this initiative, federal contractors with 50 or more employees are expected to have at least 7% of their workforce identify as having a disability. Unfortunately, only 13% of organizations met this goal in 2015. By conducting a survey of 472 individuals, the present study examined how people with and without disabilities interpret the Voluntary Self-Identification of Disability (VSD) form during the job application process. Specifically, respondents inferred positive (e.g., accommodations), negative (e.g., discrimination), neutral (e.g., person-job fit), and conflicting interpretations (e.g., a mix of positive and negative interpretations) of the VSD form.
Further, nearly 60 percent of applicants perceived the VSD form as a strategy to decrease the number of people with disabilities rather than increase. With insight on organizational signals, employers and policymakers can better design and develop recruitment materials to improve the application process for people with disabilities.
‘A consciousness of unknown things – of reason overthrown’: Epilepsy and the Unreasoning Body in Edward Lear’s Nonsense Poetry
Authors: Mackenzie Hazel
Published: June 2023

No abstract available.
Against Productivity & Liberal Pity: A Case Study in Prison Abolition & Disability Justice
Authors: Miller Autumn
Published: June 2023

No abstract available.
Evaluation of the performance of an unmanned aerial vehicle with artificial intelligence support and Mavlink protocol designed for response to social incidents response
Authors: Toren Murat , Mollahasanoğlu Hakkı , Çepni Mehmet , Kına Mücahit
Published: June 2023

The unmanned aerial vehicle name is TOMHA, which was developed to be used in the response of social incidents, aims to support the operational activities of security forces in response to social incidents, to expand their domination areas, to detect incidents that may disturb social peace in advance and to provide rapid intervention with the new unmanned aerial vehicle technologies developed. The scope of the TOMHA system designed was kept comprehensive compared to other unmanned aerial vehicles and the scope includes intervention to social events, ordering in local administrations, defense, reconnaissance and attack activities in military operations, inspections arranged for public interest, AFAD and service areas, forest fires detection and intervention, and public order operations. This TOMHA is being developed using the Pixhawk flight control card and the jetson nano artificial intelligence card. In addition to these cards, it has the feature of manual or artificial intelligence supported autonomous flight thanks to GPS, telemetry, FPV transceiver module, camera systems and national software to be used. It is controlled through the controller using RC communication channel for manual use. TOMHA has a flight time of 13.6 minutes, a thrust of 4.45G and a speed of 78 km and a mileage of 4993 meters in optimum conditions. The findings obtained by the tests performed with the designed TOMHA prototype show similar results with the literature. Thanks to the national design, TOMHA stands out when it encounters other unmanned aerial vehicles. It is seen that the response of the system to the sudden changes caused by the maneuver movements in the simulation environment is very fast and it follows the changes.
Design and Analysis of a Four DoF Robotic Arm with Two Grippers Used in Agricultural Operations
Authors: Altawil Basheer , Can Fatih Cemal
Published: June 2023

Both academic and commercial interest in agricultural robots has increased recently. This is due to the fact that agricultural robots address significant issues such as seasonal labor shortages during harvest and the rising concern over environmentally friendly practices. Because of these, several distinct agricultural robots have already been created for a variety of purposes, with varying degrees of success, including monitoring, spraying, harvesting, transport, etc. As a result, agriculture automation became unfeasible and unprofitable. The purpose of this study is to provide a new methodology for multitasking in performing agriculture operations by designing a 4 Degrees of freedom (4DoF) robotic arm with a new mechanism that has a different configuration with 2 grippers. We did kinematics and kinetics calculations using Denavit-Hardenberg (D-H) method with Lagrangian mechanics, and with the help of Christoffel Symbols of the First Kind, also We used Robot Operating System (ROS) to provide potential solutions using it. It is easy to be paired with other open-source technologies, such as android or IoT technologies. The robot arm can work synchronously with other hardware, sensors, cameras, and agricultural machines concerning farming operations. In conclusion, we believe that this new configuration will open a door for agricultural tasks to be easily automated and achieved using robotic technologies.
CyLearn: An Assistive Web-Based e-Learning System for Cybersecurity Skills Course
Authors:   School of Information Technology, Mapua University, Philippines, Samonte Mary Jane C. , Banganay Kevin Nicholas U. , Fernandez Karen E. , Jamena Jameela Nadine D.
Published: June 2023

Distance learning has become common in Philippines as schools have started to cater to online education due to the outbreak of COVID-19. E-learning has been adapted to provide learning materials and train students over the Internet. However, for people with impairments such as hearing and vision, this can be a problem. With this situation, the study developed an e-learning application with an assistive laboratory for assessments, specifically for college students. The subject matter used for the developed system is cybersecurity. cybersecurity is now one of the most in-demand courses due to the rising cases of cyberattacks. The developed system allows students to learn cybersecurity and conduct laboratory exercises in a virtual machine with text-to-speech and closed-caption technology. The study used two post-tests in a controlled group of respondents to determine if the developed system accommodates online cybersecurity learning compared to the traditional learning methods available. Comparing scores from the first group who used the developed system to the second group who used the current learning methods shows that the former received higher scores and has deemed the developed system. The developed system that has presented a guided cybersecurity learning scenario is more effective than current learning methods. Security testing was applied in this study to identify potential vulnerabilities and possible security risks in e-learning systems like this.
A Study on the Correlations between English Speaking Self-Concept and English Classroom Speaking Anxiety of Non-English Major Freshmen
Authors: Yang Tianyun , Liu Fei
Published: June 2023

English speaking self-concept and English classroom speaking anxiety are two important factors impacting learners’ English acquisition. This research investigates the relationship between English speaking self-concept and English classroom speaking anxiety on non-English first-year students. Questionnaires were adopted as the main instruments. The results show that there does exist a negative correlation between English classroom speaking anxiety and English speaking self-concept among non-English first-year students, while such kind of relation is not strong.
Unlocking Green and Just Hydrogen in Latin America and the Caribbean
Authors: Gischler Christiaan , Boeck Daza Eric Fernando , Galeano Paola , Ramírez Michelle , Gonzalez Julian , Cubillos Fernando , Hartmann Nuria , Pradelli Valentina , Márquez Juan Sebastián , Gutiérrez Juan Antonio , Juarez Hermosillo Juan Gerardo , Alonso Rodriguez Carolina , Souilla Laura , Rabinovich Julieta
Published: June 2023

This study provides an overview of the key findings and recommendations from a comprehensive document on the deployment of low-carbon hydrogen (GLCH) in Latin America and the Caribbean (LAC). It highlights the potential of LAC to become a global leader in GLCH production, leveraging its abundant renewable energy resources and existing infrastructure. The document emphasizes the importance of national strategies, supportive policies, and investments in infrastructure and research to unlock this potential. It also explores the challenges and opportunities associated with GLCH production, including electrolyzers, renewable energy integration, and the development of value chains for GH2 derivatives. The Inter-American Development Bank's (IDB) efforts in providing technical and financial assistance, promoting GLCH adoption, and establishing a regional certification scheme are discussed. The final considerations emphasize regional cooperation, social and environmental considerations, cost reduction through renewable energy development, streamlined environmental permitting processes, prioritization of GLCH derivatives, and partnerships across the GLCH value chain. Overall, the document aims to guide LAC in realizing its potential as a global player in the GLCH market while ensuring a just and sustainable energy transition.
Modeling canopy cover and aboveground net primary production using soil factors in rangelands of Ardabil province, Iran
Authors: Dadjou Farid , Ghorbani Ardavan , Moameri Mehdi , Arzani Hosein , Andalibi Lida , Mostafazadeh Raoof , Hazbavi Zeinab
Published: June 2023

Canopy cover (CC) and the aboveground net primary production (ANPP) vary under the influence of various environmental factors. They underscore ecological sustainability under different environment-human interactions. Towards this, the present study aimed to model the CC and ANPP of different plant functional types (PFTs) and their total using the soil attributes in the northwest (Ardabil province) rangelands of Iran. According to ecoregions and plant types and environmental factors, sampling was taken at the peak stage of plant growth from 2016 to 2020 using 1-m2 plots. For each transect, a soil sample was taken and transferred to the soil laboratory and the various attributes were measured. Maps of soil attributes were prepared using the inverse distance weighting (IDW) method. Differences in CC and ANPP of PFTs among soil attributes were analyzed using the paired sample t-test. Linear multiple regression was used for modeling the soil attributes. Total CC and ANPP were prepared in two ways (i.e., regression and PFTs maps summing). The accuracy assessment of the maps was calculated by using the criteria of mean absolute error (MAE), mean deviation error (MDE), and root mean squared error (RMSE). The obtained results were acceptable (value < 7). The difference between the modeled and measured mean values of CC was equal to –0.03% for grasses, –0.01% for forbs, +0.03% for shrubs, 0% for totalregression model, and +0.06 for totalPFTs maps summing. Additionally, this difference in terms of the ANPP was equal to 0 kg/ha for grasses, +0.02 kg/ha for forbs, –0.09 kg/ha for shrubs, –0.02 for totalregression model, and +0.02 kg/ha for totalPFTs maps summing. The present results are applicable to managing the balance between supply and demand of rangeland products and they can be used from carbon management perspectives.
Involvement of Rictor/mTORC2/Akt/GLUT4 pathway in the regulation of energy metabolism in the gastric smooth muscle of diabetic rats
Authors: Yan Sun , Zheng Yu-Rong , Jin Zheng , Zhang Mo-Han , Cui Xiang-Shu
Published: June 2023

Diabetes mellitus can be accompanied by a variety of complications. The purpose of the present study was to characterize the Rictor/mTOR complex 2 (mTORC2)/Akt/glucose transporter 4 (GLUT4) pathway and its effects on energy metabolism in the gastric smooth muscle of diabetic rats. Diabetes was induced in rats using streptozotocin and their phenotype was compared with untreated rats. The relationship between gastric motility and energy metabolism was analyzed by comparing the contraction and ATP metabolism of muscle strips. Western blotting was used to detect the expression of key proteins in the pathway. The diabetic rats demonstrated less frequent and less powerful gastric smooth muscle contractions. The concentrations of ADP, AMP, and ATP, and the energy charge in gastric smooth muscle changed in different periods of diabetes, and these changes were consistent with changes in mechanistic target of rapamycin (mTOR) protein content. The expression of the key intermediates in signal transduction in the Rictor/mTORC2/Akt/GLUT4 pathway also underwent significant changes. Rictor protein expression increased during the development of diabetes, but the activation of mTORC2 did not increase with the increase in Rictor expression. GLUT4 translocation is regulated by Akt and its expression change during the development of diabetes. These findings suggest that altered energy metabolism is present in gastric smooth muscle that is associated with changes in the Rictor/mTORC2/Akt/GLUT4 pathway. Rictor/mTORC2/Akt/GLUT4 pathway may be involved in the regulation of energy metabolism in the gastric smooth muscle of diabetic rats and the development of diabetic gastroparesis.
The role of USP1 deubiquitinase in the pathogenesis and therapy of cancer
Authors: Antonenko Svitlana , Zavelevich Michael , Telegeev Gennady
Published: June 2023

Ubiquitin-specific protease 1 (USP1) is an important deubiquitinating enzyme (DUB) involved in the maintenance of genome integrity, cell cycle, and cell homeostasis. USP1 overexpression is a characteristic feature of various cancers, correlating with a poor prognosis. The review summarizes the recent knowledge in understanding the role of deubiquitinase USP1 in the stabilization of oncoproteins and tumor suppressors, as a critical event in cancer development and progression. The putative mechanisms of USP1 involvement in some prevalent human cancers are discussed. The numerous data demonstrate that inhibition of USP1 suppresses the proliferation and viability of malignant cells, sensitizes them to radiation and increases their sensitivity to various chemo-therapeutic agents, which opens up new opportunities for combined therapy of malignant neoplasms.
ANTIQUE CERAMICS FROM THE BURIALS OF THE SINDIAN BURIAL GROUND AT ART. ANAPA (ON THE QUESTION OF THE INITIAL STAGE OF GREEK-BARBARIAN CONTACTS IN THE KUBAN AND EAST AZOV REGION)
Authors:   Institute of Archaeology of the Russian Academy of Sciences, Malyshev A.A. , Novichikhin A.M. ,   Institute of Archaeology of the Russian Academy of Sciences
Published: June 2023

the article is devoted to the analysis of objects of antique ceramic imports from the burials of the early group (late VII – first half of the VI century BC) of the Sindian burial ground near the experimental farm «Anapa»: the Theos amphora and the Ionian cup. Special attention is paid to the amphora of the Theos (or the «circle of Clazomen»). The finds of similar amphorae in the burials of the Kuban and the East Azov region give reason to believe that one of the Greek emporiums through which the product contained in these amphorae got to the barbarians was the Alekseevka settlement located near Anapa. The topography of these finds outlines the direction of a stable route of movement of the nomadic population of the Early Scythian period, the final points of which were Greek settlements known as Alekseevka and Taganrog settlements.
CERAMIC STAMPS OF KNIDOS WITH THE SYMBOL «SHIP᾽S PROW» (CHRONOLOGICAL GROUP Ib)
Authors:   The Institute of Archaeology of the Russian Academy of Sciences, Jefremow N.W. , Kolesnikov A.B. ,   East Crimean Historical and Cultural Museum-Reserve, Bolonkina E.V. ,   East Crimean Historical and Cultural Museum-Reserve
Published: June 2023

in the article are collected in the form of a corpus the stamps of the initial period of the systematic marking of amphorae in Knidos - stamps with a “prora” or “ship bow” (chronological group Ib). A total of 323 stamps originating from the territory of the Bosporus, Chersonese and Olbia were taken into account. They are distributed unevenly. The main reason ist, that not all museum collections are available and processed. More than half of the stamps of our corpus have been checked against the originals and the rest are taken from IOSPE III and publications. Unfortunately, most of the IOSPE III stamps are not illustrated, moreover in many cases due to the absence of indications of museum numbers, or re-inventorying, certain difficulties arise, during comparing with items stored in museum collections. Most of the studied stamps are stored in the Kerch Museum. Additionally are also involved stamps from other regions of the Northern Black Sea and the Mediterranean areas. In general, the material presented below is the first attempt at a wide coverage of the stamps of this group, which, we hope, will simplify the cameral processing of poorly preserved specimens, and will help, by attracting additional materials, to take a fresh look at the trading activity of Cnidus in the early Hellenistic period.
PALEOGRAPHY, DATING, TEXT CRITICISM OF DOZEN CURSE INSCRIPTIONS FROM ANCIENT OLBIA PONTICA
Authors: Yailenko V.P.
Published: June 2023

at the last 25 years there are published 14 new curse inscriptions from Olbia, all with dating 4th BC. Meanwhile their majority has clear paleography of 3rd and even 2nd centuries BC. The author studies here paleography of 11 inscriptions and finds, that 4 pertains to 4th century, 3 to the end of 4th–3rd century, 3 to 3rd century and 2 to 3rd–2nd centuries BC.
Circulating serum preptin levels in women with polycystic ovary syndrome: A systematic review and meta-analysis
Authors: Bahreiny Seyed Sobhan , Harooni Elnaz , Dabbagh Mohammad Reza , Ebrahimi Reza
Published: June 2023

Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder with complex pathogenesis and metabolic complications, such as insulin resistance. Among the new markers, preptin seems to play a significant role in metabolic disorders.
Objective: This meta-analysis was conducted to determine the relationship between circulating preptin levels and PCOS.
Materials and Methods: A systematic review and meta-analysis was performed to identify relevant articles in electronic databases such as PubMed, Web of Science, Scopus, Cochrane, EMBASE, and the Google Scholar search engine, using a predefined search strategy. A random-effects model was used to combine standard mean difference (SMD) and 95% CI to compare results between groups. Metaregression and subgroup analysis were also performed to reveal the sources of heterogeneity.
Results: The meta-analysis encompassed a total of 8 studies and 582 participants. The results indicate a statistically significant association between PCOS and serum preptin levels, with a pooled standardized mean difference (SMD = 1.35; 95% CI: 0.63- 2.08; p < 0.001). Further analysis suggested a significant difference in serum preptin levels between women with PCOS and higher homeostatic model assessment for insulin resistance ratio (SMD = 2.40; 95% [CI]: 1.17-3.63; p < 0.001) within the subgroup.
Conclusion: Our meta-analysis shows that increased serum preptin levels are associated with PCOS, suggesting that preptin may be related to the pathogenesis of PCOS and may be recognized as a novel diagnostic biomarker for PCOS. However, further studies are needed to confirm our results.
Key words: Polycystic ovary syndrome, Proinsulin-like growth factor II, Preptin, Meta-analysis.
Does dual trigger improve euploidy rate in normoresponder? A cross-sectional study
Authors: Kopuk Sule Yildirim , Korun Zeynep Ece Utkan , Yuceturk Aysen , Karaosmanoglu Ozge , Yazicioglu Caglar , Tiras Bulent , Cakiroglu Yigit
Published: June 2023

Background: With the introduction of the dual triggering-gonadotropin-releasing hormone (GnRH) analog and recombinant human chorionic gonadotropin (hCG) combination, women with a history of low mature oocyte proportion and empty follicle syndrome were shown to benefit from the dual trigger.
Objective: To investigate whether dual triggering of oocyte maturation with a GnRH agonist (GnRHa) combined with hCG can affect the euploidy rate and improve in vitro fertilization outcomes for normoresponder women.
Materials and Methods: In this cross-sectional study, 494 women who underwent controlled ovarian stimulation with hCG (n = 274) or dual triggering (hCG+GnRHa, n = 220) at Acibadem Maslak hospital, Assisted Reproductive Unit, from January 2019- 2022 were enrolled in this study. Preimplantation genetic testing for aneuploidy was performed on all participants.
Results: Both groups had similar baseline and clinical characteristics. Of the 881 embryos biopsied, 312 (35.4%) were reported as euploid in the hCG trigger group; in the dual trigger group, 186 (29.8%) of 623 screening embryos were reported as euploid. The hCG group had a higher euploidy rate per biopsied embryo, although the difference was not statistically significant (31.4 ± 26.5 vs. 26.5 ± 33.3, p > 0.05).
Conclusion: In normoresponders, adding GnRHa for final follicular maturation to hCG did not improve the euploidy rate.
Key words: Gonadotropin-releasing hormone, Chorionic gonadotropin, Preimplantation screening, Aneuploidy.
Assessing the risk factors and management outcomes of ectopic pregnancy: A retrospective case-control study
Authors: Tarafdari Azadeh , Bandarian Mahin , Hantoushzadeh Sedigheh , Hadizadeh Alireza , Shahsavari Saeedeh , Razavi Maryam alsadat
Published: June 2023

Background: Ectopic pregnancy (EP) is the implantation of a fertilized egg outside the uterine cavity or in an unusual location. According to the clinical case reports, hormonal contraceptive failures may be related to emergency contraceptives and EP. EP may be treated medically, surgically, or expectantly. Currently, there is no consensus regarding whether a multiple- or double-dose regimen with methotrexate (MTX) or an additional dose could be more effective than a single-dose regimen.
Objective: This study aimed to assess risk factors and treatment outcomes for EP.
Materials and Methods: This case-control study was conducted in Tehran, Iran from March 2020 to March 2021. The case group was comprised of all EP-diagnosed cases (n = 191). Based on the levels of β-human chorionic gonadotropin, MTX was administered to stable individuals with no surgical indications. Risk factors were assessed through 2 control groups: intrauterine pregnancy (n = 190) and nonpregnant groups (n = 180).
Results: The medical treatment significantly improved with an extra dose of MTX, especially in individuals with higher β-human chorionic gonadotropin concentrations and gestational age > 7.5 wk (p = 0.002). Considering risk factors, it is assumed that hormonal contraceptive failures, including both oral and emergency contraceptives, may increase the EP likelihood (p < 0.001).
Conclusion: Based on our findings, we recommended an additional dose of MTX for subjects who are further along in their pregnancy. It is also concluded that failure of contraceptive pills increases the chances of EP.
Key words: Contraception, Ectopic pregnancy, Intrauterine device, Levonorgestrel.
Effect of dietary approaches to stop hypertension, and standard diets with and without curcumin on interleukin-1 alpha, 5-alpha reductase gene expressions, and androgenic and glycemic profile in polycystic ovary syndrome women undergoing IVF
Authors: Zohrabi Tayebeh , Sheikhha Mohammad Hasan , Jambarsang Sara , Nadjarzadeh Azadeh , Aflatoonian Abbas , Mozaffari-Khosravi Hassan
Published: June 2023

Full Title: Effect of dietary approaches to stop hypertension, and standard diets with and without curcumin on interleukin-1 alpha, 5-alpha reductase gene expressions, and androgenic and glycemic profile in polycystic ovary syndrome women undergoing in vitro fertilization treatment: A study protocol
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases with major reproductive and metabolic complications with an impact on public health. Hyperandrogenism and chronic inflammation have been suggested as the leading cause of pathophysiology and clinical manifestations associated with PCOS. It seems that the altered expression of genes involved in the synthesis of proinflammatory cytokine and androgens contribute to the promotion of PCOS.
Objective: This trial aims to determine the effects of dietary approaches to stop hypertension (DASH) and standard diets with and without curcumin supplementation on the gene expression of interleukin (IL)-1α alpha, IL-5α reductase and androgenic and glycemic profile among PCOS patients, who are candidates for in vitro fertilization.
Materials and Methods: 96 infertile women with PCOS, aged 18-40 yr, will participate in this randomized, placebo-controlled clinical trial. Based on treatment conditions and body mass index, the participants will be randomly divided into 4 equal groups using a randomized block design. They will receive a DASH or standard diet containing 52% carbohydrate, 18% protein, and 30% total fat, with the same prescribed sodium, plus 500 mg twice daily curcumin or placebo for 12 wk. The mRNA expression of IL-1α, 5α reductase, and androgenic and glycemic profiles will be measured at baseline and at the end of the study.
Conclusion: Concomitant administration of DASH diet and curcumin supplementation may reduce IL-1α, 5α reductase gene expressions, and improve glycemic and androgenic profiles.
Key words: Polycystic ovary syndrome, Dietary approaches to stop hypertension, Curcumin, Fertilization in vitro, Gene expression.
Ubezpieczeniowe metody finansowania realizacji ryzyka środowiskowego przedsiębiorstw w Polsce
Authors: Hęćka-Sadowska Aleksandra
Published: June 2023

Zaostrzone regulacje prawne (zasada „zanieczyszczający płaci”) i rosnące standardy odpowiedzialności biznesu powodują, że problematyka zapobiegania szkodom w środowisku i ich finansowania przez przedsiębiorstwa jest wciąż niewystarczająco rozpoznana. Monografia stanowi teoretyczno-empiryczne studium w nowatorski sposób rozwijające dyskusję nad trudnym i złożonym zagadnieniem ryzyka środowiskowego oraz metod jego kontroli w przedsiębiorstwach. O oryginalności opracowania przesądza konstruktywistyczne podejście do pojęcia ryzyka służące wypracowaniu nowych praktyk w zakresie środowiska jako dobra wspólnego, jak również badanie empiryczne dotyczące postrzegania ryzyka i wykorzystania ubezpieczeń środowiskowych przez duże przedsiębiorstwa prowadzące działalność w Polsce. W szerszym zakresie tematem monografii jest coraz istotniejsza problematyka ochrony środowiska i odpowiedzialności za jego zanieczyszczenie, a zwłaszcza ubezpieczeniowych metod finansowania realizacji ryzyka środowiskowego wykorzystywanych przez przedsiębiorstwa obok stosowania fizycznych środków jego kontroli. Autorka rozpoznaje nie tylko stan prawny czy politykę ekologiczną państwa, ale także determinanty postrzegania ryzyka środowiskowego przedsiębiorstwa, wśród których wymienia m.in. wiedzę, posiadane systemy, prezentowane wartości i doświadczenie. Ponadto bada rynek ubezpieczeń, porównując dostępne instrumenty, a także zarysowuje pożądane kierunki edukacji i polityki w tym zakresie. Wnioski mogą pomóc przedsiębiorcom sprostać wymogom odpowiedzialności finansowej za szkody w środowisku i uratować wizerunek, a także wesprzeć na różnych poziomach strategię zrównoważonego rozwoju. Publikacja jest skierowana głównie do akademickich badaczy problematyki zarządzania ryzykiem i ubezpieczeń, dydaktyków, ekspertów i konsultantów, ubezpieczycieli, przedsiębiorców i polityków mających wpływ na gospodarkę, zwłaszcza zainteresowanych wspieraniem zrównoważonego rozwoju. Wydanie dofinansowane ze środków Ministerstwa Edukacji i Nauki w ramach programu Doskonała nauka.
A SALVAGUARDA DO PATRIMÔNIO ARQUEOLÓGICO E POSSÍVEIS CAMINHOS PARA UM OUTRO TURISMO PEDAGÓGICO
Authors: Oliveira Wagner Araújo , Santos Rafaela Cláudia dos
Published: June 2023

O presente trabalho tem como objetivo central apresentar as principais ações contributivas do Museu Histórico de São Vicente (MHSV) para a salvaguarda do patrimônio arqueológico, contribuindo para o fomento de um outro turismo pedagógico. A pesquisa possui uma abordagem qualitativa e de caráter exploratório e descritiva. Quanto ao plano de coleta de dados, foi realizada a pesquisa bibliográfica, bem como visita in loco, realização de entrevistas com gestores e a técnica de análise utilizada foi a descritiva. O MHSV tem como propósito contribuir com a salvaguarda da memória e história oral, a valorização da arte e da cultura e a difusão do patrimônio cultural, material e imaterial do município, além disso, tem associado suas atividades com a prática do turismo pedagógico promovendo ações educativas elucidando a importância do fortalecimento da salvaguarda do patrimônio arqueológico.
Los tránsitos migratorios de las travestis/trans peruanas hacia Europa
Authors: Pérez Ripossio Ramiro N.
Published: June 2023

El artículo analiza los tránsitos migratorios que las travestis/trans peruanas llevan cabo luego de abandonar sus contextos de origen. Al experimentar diferentes discriminaciones, vulnerabilidades y violencias en el Perú, deciden desplazarse para vivir en mejores condiciones. Por eso, migran al Área Metropolitana de Buenos Aires (AMBA), Argentina, y luego de un tiempo se desplazan a Europa, donde transitan experiencias de diverso carácter. La migración de las travestis/trans peruanas es inestable como consecuencia de las hostilidades que experimentan en los destinos receptores. En consecuencia, deben ir a buscar escenarios menos hostiles, por lo que la movilidad representa una de las principales características de sus trayectorias biográficas. Se emplea una metodología cualitativa que utiliza la entrevista en profundidad y, de manera complementaria, la observación participante. Se confeccionó un muestreo teórico y se empleó el software ATLAS.ti para procesar y analizar la información mediante el método de la comparación constante. Se halló que para algunas entrevistadas migrar al AMBA representa un trampolín hacia Europa, dado que les permite mejorar la posición en el espacio social y acceder a capitales. Sin embargo, se descubrió que otras travestis/trans tuvieron experiencias negativas. En conclusión, Europa representa un claroscuro que articula vivencias de diferente carácter, vinculando anhelos, oportunidades y desilusiones.
La semántica de la sociedad regional y el problema del dualismo interno/externo en los análisis de América Latina
Authors: Gonnet Juan Pablo
Published: June 2023

En este artículo proponemos que la semántica de sociedad regional se ha establecido en un supuesto ampliamente difundido para la conceptualización de América Latina. Esta semántica considera que los límites geográficos y espaciales son significativos para la delimitación de las realidades sociales. De esta manera, permite distinguir entre realidades internas y externas, reconociendo su valor simultáneo para la comprensión de las dinámicas sociales que se despliegan en la región. En efecto, es posible reconstruir la diversidad de teorizaciones sobre América Latina como formas alternativas en que se han concebido los vínculos entre lo interno y lo externo. El trabajo busca desarrollar estas hipótesis, al tiempo que avanza en la evaluación de los límites teóricos y empíricos de la semántica. Se concluye acerca de la necesidad de avanzar hacia una concepción no regionalista de la sociedad para aproximarse a América Latina.
Violent Victimization During Childhood in the United States: Associations With Revictimization and Health
Authors: Basile Kathleen C. , Chen Jieru , Smith Sharon G. , Clayton Heather B. , Simon Thomas R. , Mercy James A.
Published: June 2023

Childhood violence victimization is a serious adverse childhood experience with lasting health impacts. This study examined the prevalence and characteristics of five forms of childhood violence victimization and their association with revictimization and negative health conditions among adults. Data are from the 2010–2012 National Intimate Partner and Sexual Violence Survey. Age at first victimization and perpetrator sex were assessed; adjusted odds ratios assessed associations with revictimization and health. Ages 14–17 were the most common age at first victimization for most violence types; almost half of male (46.7%) and a quarter of female (27.0%) rape victims reported first victimization before age 10. Most victimization was associated with revictimization and negative health, controlling for adult victimization. Primary prevention of childhood violence may reduce later health risks.