bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of the Earth’s structure based on intermediate-period surface wave recordings of tidal gravimeters: a case study
Authors: Karkowska Kamila , Wilde-Piórko Monika
Published: October 2022

Tidal gravimeters can detect intermediate-period surface waves with high accuracy. Three gravimetric stations with estimated transfer functions and co-located with seismic stations were selected: two in Belgium (Membach and Rochefort, in Western Europe) and one in Germany (Black Forest, in Central Europe). The compatibility of gravimetric and seismic recordings of earthquakes in the period range of 10-180 s has been presented. The series of monochromatic signals separated from surface waves for selected events have been calculated using the multiple-filtering procedure, and averaged fundamental-mode Rayleigh wave group-velocity curves have been estimated on a regional scale. Next, averaged dispersion curves for three regions (Italy, Greece, and Western Turkey) were inverted by weighted linear inversion methods. Additionally, a quantitative analysis of resolution tests of inverted models was presented to show the capabilities of the gravimetric data to retrieve a shear-wave velocity distribution with a depth. In particular, a method for determining the depth range of the inverted model has been proposed. Results obtained based on gravimetric data were verified by results from seismic data obtained by applying the same procedure. This study shows the novel application of tidal gravimetric data in the determination of the regional Earth’s structure based on intermediate-period surface waves recordings, as well as a comprehensive approach to the quantitative estimation of a final model resolution.

Graphical Abstract
Alcohol consumption and health-related quality of life in the US during the COVID-19 pandemic: a US national survey
Authors: Wittenberg Eve , Labutte Collin , Thornburg Benjamin , Gebreselassie Abraham , Barbosa Carolina , Bray Jeremy W.
Published: October 2022

Background

Alcohol consumption has changed during the COVID-19 pandemic yet the impacts on alcohol-related outcomes, and specifically health-related quality of life, are not completely known. Our objective was to assess the association between alcohol consumption and health-related quality of life (HRQOL) during the COVID-19 pandemic.

Method

We conducted an on-line/telephone survey of three cross-sectional samples of US adults during a nine-month stretch of the pandemic, from August 2020 through April 2021, collecting data on drinking—current quantity/frequency and change since prior to pandemic, HRQOL (using the SF-6D), and perceived impact of the pandemic on respondents’ lives—overall impact and disruptions across various dimensions (job loss, school closures, social isolation, loss of income). We pooled the data from the three administrations and applied survey weights to reflect the US population. We described drinking behavior and pandemic impact, and regressed HRQOL on alcohol consumption risk level (per World Health Organization categories), change in drinking since pre-pandemic, and pandemic impact using weighted least squares, controlling for respondents’ demographic characteristics. We tested the significance of categorical variables using Wald tests at a p-value of 0.05.

Results

Among 3,125 respondents, weighted to reflect the US population, 68% reported drinking during the pandemic and 40% reported a change in drinking from pre-pandemic level (either increased or decreased). Mean HRQOL among our sample was 0.721 (SD 0.003). Any change in drinking from pre-pandemic level was independently associated with significantly lower HRQOL compared to never drinking (pre or during pandemic), from − 0.0251 points for decreased/stopped drinking to -0.0406 points for increased drinking (combined levels’ Wald test F = 10.62, p < 0.0000). COVID-19 pandemic related impacts/disruptions were associated with HRQOL decrements ranging from − 0.0834 to -0.1340 (Wald test F = 64.34, p < 0.0000).

Conclusion

The US population HRQOL was substantially lower during the pandemic than reported a decade earlier (mean = 0.79 in 2012-13). While pandemic-related impacts and disruptions may explain a large part of this decrement, changes in drinking—and the associated implications of such changes–might also play a role. Both individuals who reduced their drinking during the pandemic and those who increased consumption may be at risk of poor HRQOL.
Wearing a KN95/FFP2 facemask induces subtle yet significant brain functional connectivity modifications restricted to the salience network
Authors: Haller Sven , Montandon Marie-Louise , Rodriguez Cristelle , Giannakopoulos Panteleimon
Published: October 2022

Background

The use of facemasks is one of the consequences of the coronavirus disease 2019 (COVID-19) pandemic. We used resting-state functional magnetic resonance imaging (fMRI) to search for subtle changes in brain functional connectivity, expected notably related to the high-level salience network (SN) and default mode network (DMN).

Methods

Prospective crossover design resting 3-T fMRI study with/without wearing a tight FFP2/KN95 facemask, including 23 community-dwelling male healthy controls aged 29.9 ± 6.9 years (mean ± standard deviation). Physiological parameters, respiration frequency, and heart rate were monitored. The data analysis was performed using the CONN toolbox.

Results

Wearing an FFP2/KN95 facemask did not impact respiration or heart rate but resulted in a significant reduction in functional connectivity between the SN as the seed region and the left middle frontal and precentral gyrus. No difference was found when the DMN, sensorimotor, visual, dorsal attention, or language networks were used as seed regions. In the absence of significant changes of physiological parameter respiration and heart rate, and in the absence of changes in lower-level functional networks, we assume that those subtle modifications are cognitive consequence of wearing facemasks.

Conclusions

The effect of wearing a tight FFP2/KN95 facemask in men is limited to high-level functional networks. Using the SN as seed network, we observed subtle yet significant decreases between the SN and the left middle frontal and precentral gyrus. Our observations suggest that wearing a facemask may change the patterns of functional connectivity with the SN known to be involved in communication, social behavior, and self-awareness.
Penicillium simplicissimum and Trichoderma asperellum counteract the challenge of Puccinia striiformis f. sp. tritici in wheat plants
Authors: Esmail Samar Mohamed , Draz Ibrahim Sobhy , Saleem Muhammad Hamzah , Mumtaz Sahar , Elsharkawy Mohsen Mohamed
Published: October 2022

Background

Yellow (stripe) rust, caused by Puccinia striiformis f. sp. tritici (Pst), is an economic disease of wheat. Growth-promoting fungi (GPF) such as Trichoderma asperellum and Penicillium simplicissimum have been investigated for their potential to control yellow rust and their involvement in gene expression of four PR proteins for all-stage resistance.

Results

Wheat plants (cv. Sids-12) treated individually with each of the biocontrol agents, P. simplicissimum and T. asperellum, at 24 and 48 hpi showed a resistance response (infection type = 2) to yellow rust, compared to the non-treated plants, which showed highly susceptible response (infection type = 9). Both biocontrol agents induced resistance against yellow rust on wheat plants, exhibiting a moderate resistance (10 MR) and reduced the colony size of Pst (0.6 mm2). Moreover, P. simplicissimum and T. asperellum increased (P ≤ 0.05) the grain yields of wheat plants infected with Pst. Scanning electron microscope (SEM) of yellow rust infected wheat leaves treated with P. simplicissimum and T. asperellum at 24 and 48 hpi showed hyperparasitism on Pst urediniospores and inhibition of the spore germination. Expressions of pathogenesis-related (PR) protein genes, PR1, PR2, PR3 and PR4 were higher in wheat plants treated with both biocontrol agents than the non-treated checks.

Conclusion

P. simplicissimum and T. asperellum exhibited biocontrol potential against yellow rust disease caused by P. striiformis f. sp. tritici (Pst) on wheat plants. It was found that wheat defence mechanism against Pst was activated by a high expression of PR protein genes induced by both biocontrol agents.
Fluoroscopy-assisted epidural catheter placement: the effect of dye distribution in preoperative epidurograms on postoperative analgesia
Authors: Abdel-Moneem Mohamed Sobhy , Seam Elham Abdel Latif Hussein , Eskander Fahmy Saad Latif , Hamza Amr Hosny , El-Fawal Sanaa M.
Published: October 2022

Background

Postoperative epidural analgesia provides superior postoperative analgesia at rest and with activity, compared with systemic opioids. However, the impact of postoperative epidural analgesia on postoperative morbidity and/or mortality remains controversial, because of the sub-optimal reliability of epidural catheters that are placed preoperatively and used for postoperative pain control. The present study used the technique of lumbar epidurography. The study aims to better understand the possible correlation between the fluoroscopic characteristics of epidural catheters following injection of contrast medium and the postoperative functional characteristics regarding analgesia. In this single-arm clinical trial, 70 patients, aged 50 to 75 years old, underwent surgical urological procedures, involving incisions up to T8 dermatome, under combined general and epidural anesthesia. At the L2-L3 level, the epidural space was reached using the loss of resistance technique before general anesthesia was induced. The catheters were threaded upwards for 4–6 cm. Preoperative epidurograms were then done by injecting a 3-ml contrast medium OmnipaqueTM (240 mg I/ml) in the epidural catheters. The epidurograms were investigated for the location of the catheter tip in relation to the vertebral body, the extent of dye spread, laterality of dye spread (midline, right, or left), and the presence or absence of dye spread anterior to the spinal cord on the lateral image. The patients were followed postoperatively while epidural analgesia was infused.

Results

Both the postoperative epidural infusion and postoperative visual analog scale (VAS) scores were lower when catheter tips ended at L1 than when they ended at L2. As the contrast’s vertical spread increases in preoperative epidurograms, the analgesic infusion rate and VAS score decrease, and the number of dermatomes insensitive to cold increases. Epidurographically right-sided catheters showed more dermatomes deficient to cold sensations on the right side, compared with mid-line and left-sided catheters. Restriction of contrast to the posterior epidural space was associated with lower VAS scores and wider anesthesia to cold.

Conclusions

The use of epidurography to study epidural catheters may have the potential advantage of predicting the functionality of catheters and improving the reliability of postoperative epidural analgesia.
In silico detection of Cucurbitacin-E on antioxidant enzymes of model organism Galleria mellonella L. (Lepidoptera: Pyralidae) and variation of antioxidant enzyme activities and lipid peroxidation in treated larvae
Authors: Ercan Fahriye Sümer , Baş Hatice , Azarkan Serap Yalçın
Published: October 2022

Background

In silico studies further provided predictive binding properties of selected ligands for inhibition of target protein. In the study, molecular binding poses of Cucurbitacin-E and antioxidant enzymes (glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx) and acetylcholinesterase (AChE) ofGalleria mellonellawere determined in silico. Cucurbitacins are the most important components ofEcballium elaterium. The first cucurbitacin isolated from the plant was Cucurbitacin-E. In this study, the toxic effect ofE. elaterium(L.) A. Rich. (Cucurbitaceae) fruit juice onG. mellonella(Lepidoptera: Pyralidae) larvae, which is known as a good model insect, was also detected, and its effect on antioxidant enzyme activities and lipid peroxidation was revealed.

Results

The plant fruit juice was tested on the target larvae ofG. mellonellawith different doses for 24 h. After the application, mortality rate, LC50, LC90and LC99values, the malondialdehyde (MDA) level and the activity changes of antioxidant enzymes were determined. Mortality increased with the increasing concentration of fruit juice. Also, increasing doses of essential oil caused decreasing in SOD, CAT, GST GPx, GR and AChE activities and increasing in MDA levels. As a result of in silico studies, maximum binding energy was obtained fromG. mellonellaCAT enzyme with Cucurbitacin E as a ligand.

Conclusions

This is the first study to demonstrate the in silico binding potential of Cucurbitacin E onG. mellonellaenzymes. The results indicate thatE. elateriumcan be used againstG. mellonellain a pest control program.

Graphical Abstract
Pharmacognostic evaluation of Eranthemum indicum extracts for its in-vitro antioxidant activity, acute toxicology, and investigation of potent bioactive phytocompounds using HPTLC and GCMS
Authors: Nonglang Flavius Phrangsngi , Khale Abhijeet , Wankhar Wankupar , Bhan Surya
Published: October 2022

Background

Northeast India has a rich resource of herbal plants, and it is essential to validate their therapeutic activity with proper scientific evidence. This study aims to identify active phytocompounds found in the extracts ofEranthemum indicum(E. indicum) and to determine its antioxidative activities and toxicity.

Results

In vitrofree radical scavenging activity of the aqueous extract (AE) and methanol extract (ME) ofE. indicum(leaves) was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic-acid (ABTS), ferric reducing antioxidant power (FRAP), and total antioxidant activity (TAC). ME depicted better inhibitory concentration when compared to AE. This indicates the effective extraction capacity of methanol, which is consistent with the fact that ME had a higher polyphenol and flavonoid, resulting in their antioxidative activity. HPTLC analysis using the solvent system of ethyl acetate/methanol/ammonia 28–30% (40:10:10) showed better fingerprinting separation, especially in the ME. Furthermore, DPPH radical solution, when used as a derivatizing agent in HPTLC analysis, confirmed that ME has betterin vitroantioxidant activities than AE. GCMS analysis of AE identified 3-beta-hydroxy-5-cholen-24-oic-acid as active compound, while in ME Beta.-l-arabinopyranoside and 2-methyl-3-(3-methyl-but-2-enyl)-2-(4-methyl-pent-3-enyl)-oxetane were identified as the major bioactive compound. Acute toxicological investigations have shown that bothE. indicumextracts have a high L.D. 50 value of 1533 mg/kg b.w for AE and 1567 mg/kg b.w for ME making them safe and non-toxic.

Conclusions

Extraction and identification of these phytocompounds in the extracts ofE. indicumcan help us scientifically document its medicinal importance, and its benefit in pharmaceutical industries. Since it showed promising free radical scavenging activity, it can also be a potent antioxidant source.
Graded Cardiac Response Criteria for Patients With Systemic Light Chain Amyloidosis
Authors: Muchtar Eli , Dispenzieri Angela , Wisniowski Brendan , Palladini Giovanni , Milani Paolo , Merlini Giampaolo , Schönland Stefan , Veelken Kaya , Hegenbart Ute , Geyer Susan M. , Kumar Shaji K. , Kastritis Efstathios , Dimopoulos Meletios A. , Liedtke Michaela , Witteles Ronald , Sanchorawala Vaishali , Szalat Raphael , Landau Heather , Petrlik Erica , Lentzsch Suzanne , Coltoff Alexander , Bladé Joan , Cibeira Maria Teresa , Cohen Oliver , Foard Darren , Wechalekar Ashutosh , Gertz Morie A.
Published: October 2022

PURPOSE

Binary cardiac response assessment using cardiac biomarkers is prognostic in light chain amyloidosis. Previous studies suggested four-level cardiac responses using N-terminal prohormone of brain natiuretic peptide improves prognostic prediction. This study was designed to validate graded cardiac response criteria using N-terminal prohormone of brain natiuretic peptide/brain natiuretic peptide.

PATIENTS AND METHODS

This retrospective, multicenter study included patients with light chain amyloidosis who achieved at least a hematologic partial response (PR) and were evaluable for cardiac response. Four response criteria were tested on the basis of natriuretic peptide response depth: cardiac complete response (CarCR), cardiac very good partial response (CarVGPR), cardiac PR (CarPR), and cardiac no response (CarNR). Response was classified as best response and at fixed time points (6, 12, and 24 months from therapy initiation). The study primary outcome was overall survival.

RESULTS

651 patients were included. Best CarCR, CarVGPR, CarPR, and CarNR were achieved in 16%, 26.4%, 22.9%, and 34.7% of patients, respectively. Patients in cardiac stage II were more likely to achieve CarCR than patients in cardiac stage IIIA and IIIB (22% v 13.5% v 3.2%; P < .001). A deeper cardiac response was associated with a longer survival (5-year overall survival 93%, 79%, 65%, and 33% for CarCR, CarVGPR, CarPR, and CarNR, respectively; P < .001). Fixed time-point analyses and time-varying covariates Cox regression analysis, to minimize survivorship bias, affirmed the independent survival advantage of deeper cardiac responses. Four-level response performed better than two-level response as early as 12 months from therapy initiation.

CONCLUSION

Graded cardiac response criteria allow better assessment of cardiac improvement compared with the traditional binary response system. The study re-emphasizes the importance of early diagnosis, which increases the likelihood of deep cardiac responses.
Pornoterrorism
Authors: Tyburczy Jennifer
Published: October 2022

Pornoterrorism is a form of mixed-media performance art in the Americas that combines postpornographic and transfeminist practices with political commentary often directed at the intersection of sex and terror. Through interviews with artists in Mexico City and visual and performance analysis, this article explores the short but potent history of pornoterrorism in Mexico, unpacking the genre and specifically examining why underground artists, formerly known as pornoterrorists, decided to relinquish certain aesthetic choices when confronted with the increasing violence and precarity of visual culture and everyday life throughout Mexico. Thus, while focused on Mexico and more specifically Mexico City, this article poses and seeks to answer a larger question on queer and transfeminist aesthetics and world making, namely, whether dissident art forms can lose their ability to subvert in the contexts of their changing geopolitical milieus.
Το δικαίωμα υπαναχώρησης στην πνευματική ιδιοκτησία
Authors: Τσίγκου Χρυσούλα
Published: October 2022

Η μελέτη εξετάζει υπό συγκριτικό πρίσμα τη λειτουργία της εξουσίας υπαναχώρησης σε όλες τις συμβάσεις πνευματικής ιδιοκτησίας στο αναλογικό και το ψηφιακό περιβάλλον. Εξετάζονται οι διάφορες μορφές έργων του λόγου και ιδιαίτερα οι νέες κατηγορίες ψηφιακών έργων (ιστοσελίδες, ιστολόγια, ηλεκτρονική λογοτεχνία, έργα παραγόμενα από τους χρήστες, έργα τεχνητής νοημοσύνης). Αναλύονται επίσης όλες οι συμβατικές μορφές εκμετάλλευσης με έμφαση στην εξέταση των διαφόρων μορφών ψηφιακής εκμετάλλευσης, περιλαμβανομένων των αναρτήσεων σε επιγραμμικές πλατφόρμες. Οι όροι και οι συνέπειες άσκησης της εξουσίας υπαναχώρησης ερευνώνται σε συνάρτηση με τον τρόπο εκμετάλλευσης και διατυπώνονται de lege ferenda προτάσεις για το σύστημα αποζημίωσης. Ιδιαίτερη μνεία γίνεται στα ζητήματα άσκησης της εξουσίας υπαναχώρησης στη σύμβαση εργασίας και την κληρονομική διαδοχή με αναφορά στα ειδικά καθεστώτα τα οποία τις διέπουν.
Η σημασία της έκφρασης του προσδέτη της πρωτεΐνης 1 προγραμματισμένου κυτταρικού θανάτου (PD-L1) και των κυτταροτοξικών CD8 λεμφοκυττάρων σε χαμηλής διαφοροποίησης αδενοκαρκινώματα του ενδομητρίου
Authors: Βαγιός Στυλιανός
Published: October 2022

Εισαγωγή: Η χρησιμοποίηση της ανοσοθεραπείας στη γυναικολογική ογκολογία κερδίζει σημαντικό έδαφος και είναι επιτακτική ανάγκη η αναγνώριση βιοδεικτών που θα συμβάλλουν στην αποτελεσματικότερη εφαρμογή της. Σκοπός της Μελέτης: Η αξιολόγηση της έκφρασης του PD-L1 και των CD8 λεμφοκυττάρων σε καρκινώματα ενδομητρίου χαμηλής διαφοροποίησης καθώς και η συσχέτιση των αποτελεσμάτων με κλινικοπαθολογοανατομικά χαρακτηριστικά. Μέθοδοι: Στη μελέτη συμπεριλήφθηκαν 101 ασθενείς με χαμηλής διαφοροποίησης ενδομητρικό καρκίνο που αντιμετωπίστηκε με πλήρη χειρουργική σταδιοποίηση. Η έκφραση των PD-L1 και CD8 εκτιμήθηκε με ανοσοϊστοχημεία. Αποτελέσματα: Το 46.5% αφορούσε σε ενδομητριοειδή, ενώ το 53.5% σε μη- ενδομητριοειδή καρκινώματα. Στα ενδομητριοειδή καρκινώματα παρατηρήθηκε σημαντικά υψηλότερη έκφραση τόσο του PD-L1 (p=0.042) όσο και των ενδοεπιθηλιακών CD8 κυττάρων (p=0.004) σε σχέση με τους άλλους ιστολογικούς τύπους. Δεν παρατηρήθηκαν στατιστικά σημαντικές σχέσεις μεταξύ των PD-L1 και CD8 και των υπόλοιπων υπό μελέτη κλινικοπαθολογικών χαρακτηριστικών. Η αυξημένη διήθηση με ενδο-ογκικά CD8 λεμφοκύτταρα συσχετίστηκε με μεγαλύτερη ελεύθερης νόσου επιβίωση, τόσο σε μονοπαραγοντική όσο και σε πολυπαραγοντική ανάλυση (p=0.001). Καρκινώματα αρνητικά για το PD-L1 και με αυξημένη διήθηση από CD8 λεμφοκύτταρα είχαν τη μεγαλύτερη ελεύθερης νόσου επιβίωση (p=0.032). Συμπεράσματα: Σε χαμηλής διαφοροποίησης καρκινώματα ενδομητρίου, ανεξαρτήτως του ιστολογικού τύπου, η αυξημένη διήθηση από ενδοεπιθηλιακά CD8 κύτταρα αποτελεί έναν ανεξάρτητο θετικό προγνωστικό δείκτη, και όταν συνδυάζεται με αρνητική έκφραση για το PD-L1 τότε προβλέπεται μεγαλύτερη επιβίωση ελεύθερη νόσου. Μεταστατικά καρκινώματα θετικά για το PD-L1 και με υψηλή διήθηση από CD8 λεμφοκύτταρα, τα οποία είναι κυρίως ενδομητριοειδούς ιστολογίας και εμφανίζουν μεγάλο φορτίο νέο-αντιγόνων, θα μπορούσαν να ωφεληθούν από την ανοσοθεραπεία.
Ο κοινωνικός μετασχηματισμός στην εποχή της "γενικής διάνοιας"
Authors: Παπαδόπουλος Ραφαήλ
Published: October 2022

Σημείο εκκίνησης της διατριβής είναι η διαπίστωση ότι η παρούσα παγκόσμια κρίση έχει οξύνει την εγγενή ένταση μεταξύ των δύο θεμελιακών αρχών της φιλελεύθερης δημοκρατίας, της ελευθερίας και της ισότητας, και ότι η νεοφιλελεύθερη ηγεμονία σηματοδοτεί την αποφασιστική κυριαρχία της πρώτης επί της δεύτερης. Επίσης, διαπιστώνεται ότι η κρίση της παραδοσιακής σοσιαλδημοκρατίας και η κατάρρευση του σοβιετικού κομμουνισμού έχει οδηγήσει το μεγαλύτερο μέρος της Αριστεράς διεθνώς στην αποκήρυξη βασικών παραδοχών της μαρξιστικής παράδοσης (υλιστική ανάλυση της κοινωνίας, πρωταγωνιστικός ρόλος της ταξικής πάλης και του προλεταριάτου στην κοινωνική αλλαγή με στόχο το σοσιαλιστικό μετασχηματισμό) και στην υιοθέτηση της μεταμοντέρνας-κοντρουξιονιστικής παράδοσης, με έμφαση στις μεταυλιστικές αξίες και στην πολλαπλότητα και την ενδεχομενικότητα των κοινωνικοπολιτικών αγώνων και ταυτοτήτων. Κεντρική θέση της μελέτης, που τεκμηριώνεται μέσα από την κριτική προσέγγιση δύο σύγχρονων μεταμοντέρνων ρευμάτων σκέψης, του μετα-μαρξισμού των Λακλάου-Μουφ και της «Αυτοκρατορίας» των Χαρντ-Νέγκρι, είναι ότι αυτή η μεταυλιστική στροφή, παρά τις σημαντικές προοδευτικές όψεις της, δεν παρέχει στην Αριστερά τα κατάλληλα εργαλεία θεωρητικής και πρακτικής αμφισβήτησης του καπιταλισμού και υπέρβασης της κρίσης προς όφελος της κοινωνικής πλειοψηφίας, και ότι αυτά τα εργαλεία μπορούν να εξευρεθούν στη μαρξιστική παράδοση και συγκεκριμένα στη λενινιστική θεώρηση του ιμπεριαλισμού και στη γκραμσιανή ηγεμονία, που στη σημερινή εποχή της «γενικής διανοίας» στοιχειοθετούν τη συγκρότηση του επαναστατικού υποκειμένου ως διαλεκτικής σύνθεσης του «προοδευτικού λαϊκισμού» των Λακλάου-Μουφ και του «πλήθους» των Χαρντ-Νέγκρι.
Case Report: Visualization for treatment of insomnia, anxiety, and depression caused by PTSD
Authors: Aldahadha Basim , Bani Mustafa Manar
Published: October 2022

Background: Depression and anxiety are disorders related to insomnia that generally affect quality of life, especially if they are related to traumatic events. One of the therapeutic methods that has shown effectiveness in treating depression, anxiety and insomnia associated with posttraumatic stress disorder (PTSD) is the visualization method, which is a cognitive behavioral method. The aim of this case study is to investigate the effectiveness of visualization in treating symptoms of depression, anxiety and insomnia associated with posttraumatic experiences.

Methods: Sulaiman is a university student who suffered with his family a painful traffic accident, and he has become unable to slee p. This affected his general life, so he became anxious and depressed and had nightmares when sleeping, which lasted for more than a year. He was trained on visualization exercises, including laughter, music, directed visualization, receptive visualization, programmed visualization, and others, which lasted for 17 sessions.

Results: The results showed an average improvement of 77.8% for each of the symptoms of anxiety, depression, insomnia, and the number of minutes it takes to fall asleep. The results of the nonparametric test also showed that there were statistically significant differences in the ranks of measures, as it showed z-values for each of insomnia (z= -2.32, p=0.008), depression (z= -2.54, p=0.04), anxiety (z= -3.08, p=0.03), the time taken to enter sleep (z= -2.64, p=0.04), and the time spent asleep (z= -2.44, p=0.02).

Conclusions: Sulaiman reported that he became more effective and said that depression, rumination, symptoms of anxiety and stressful thoughts had been reduced to a minimum due to learning more positive alternatives and effective and healthy fantasies.
DESIGN OF A ROBOTIC TAPING MECHANISM FOR UAV-BASED WIND TURBINE BLADE MAINTENANCE
Authors: GENOVA JOSHUA , GUPTA LAKSHAY , HOSKERE VEDHUS
Published: October 2022

Wind energy generated through wind turbines is a critical contributor towards realizing a renewable energy economy. Maximizing the efficiency of power generation from wind turbines is required to meet target generation capacities. The leading edge of wind turbine’s blade is designed such that its smooth, aerodynamic surface will produce maximum power given the size specification of the turbine. As these blades age, they typically suffer from leading edge erosion, or LEE, which is the gradual erosion of the blade’s leading edge. Not only does LEE shorten a blade’s lifespan, but it also negatively affects performance, reducing annual energy production. Application of wind blade protection tape is a frequently used solution for LEE on the damaged area. Tape application requires a crew of technicians with a lift and is considered high-risk where one mistake can lead to fatal injury. The focus of this paper is to present a method of automating the wind blade protection tape application by using a UAV with an endeffector. Specifically, the end-effector is an automatic taping mechanism that will apply wind blade protection tape to the damaged area. The paper discusses the overall robotic arm design, topology optimization, and hardware components used to create the operation for the automatic taping mechanism. The end-effector is designed to dispense tape, extend to create contact to the surface, and cut to finish the application. The rest of the arm is used for the motion of tape application vertically starting from the bottom of the damaged region. The process is completed once the damaged area has been covered with protection tape and tape has been cut. The developed end-effector demonstrates the effectiveness of the taping operation, ultimately conserving the wind blade’s lifespan and decreasing the risk of human injury.
NEW EXCITATION (MULTIPLE WIDTH PULSE EXCITATION (MWPE)) METHOD FOR SHM SYSTEMS—PART 1: VISUALIZATION OF TIME- FREQUENCY DOMAIN CHARACTERISTICS
Authors: TANSEL IBRAHIM , MODIR ALIREZA
Published: October 2022

Structural health monitoring (SHM) of additively manufactured polymer parts is challenging due to the very strong attenuation of the surface waves. To excite the part surface at a very wide frequency band in a very short time, Multiple Width Pulse Excitation (MWPE) signal was introduced. MPWE was used to excite the surface of the structure for the implementation of the Surface Response to Excitation (SuRE) method. A cross-shaped polymer part was fabricated additively for the identification of the hidden geometry of the infill. The part had four extensions with identical geometry but different internal designs. Two of the extensions had cross infills and the other two had square infills. For each type of infill, one extension had 1 mm and the other extension had 2 mm thick skin. The part was excited at the middle with WMPE excitation and the dynamic response was monitored at the end of each extension. The Short-Time Fast Fourier Transform (STFFT) was used for the analysis of the signal in the time-frequency domain. The two dimentional sum of the squares of the differences (2DSSD) was used for the classification of the signal. Compressive force and type of infill was identified accurately for all the test cases.
NEW EXCITATION (MULTIPLE WIDTH PULSE EXCITATION (MWPE)) METHOD FOR SHM SYSTEMS—PART 2: CLASSIFICATION OF TIME- FREQUENCY DOMAIN CHARACTERISTICS WITH 2DSSD AND CNN
Authors: MODIR ALIREZA , TANSEL IBRAHIM
Published: October 2022

Surface response to excitation (SuRE) and electromechanical impedance methods quantify the difference between the reference and any given spectrums by calculating the sum of the squares of differences (SSD). In part one of this study, twodimensional SSD (2D-SSD) was proposed to quantify the difference of timefrequency plots when the part was excited with the Multiple Width Pulse Excitation (MWPE) signal. In this study, neural networks and deep learning were used for the classification of structural health monitoring (SHM) signals. Since manual encoding of the 2D spectrograms is very complicated to prepare them for classification by using neural networks, deep learning has been used. In this study, the performance of deep learning was evaluated for the classification of sensory data. A cross-shaped part made of PLA was manufactured additively and the center of the part was excited with MWPE and the surface waves were monitored at the end of each extension. Tests were repeated without and with a compressive force at each extension. The recorded time-domain sensory data was converted to spectrogram images using Short-Time Fourier Transform (STFT). The spectrograms were classified with the Convolutional Neural Network (CNN) after proper training. The results showed that the hidden geometry of each extension had a distinctive effect on the characteristics of the monitored signals. CNN could classify the infill type, skin thickness, and loading conditions with better than 92 % accuracy when the responses of the 20 pulses in the MWPE signal were considered.
RESEARCH ON STRUCTURAL HEALTH DIAGNOSIS TECHNOLOGY OF COKE DRUM BASED ON MONITORING DATA
Authors: TANG FANGXIONG , YANG DONGMING , DING KEQIN , CHEN LI
Published: October 2022

The coke drum, work under high temperature, coke in and out with hot and cold distress through the cycle of 500℃ to 50℃, is the core reactor of the delayed coking device. Typical failure modes of bulge deformation of tower, low cycle fatigue crack of weld, material aging, the tower body bending and inclining is easy to be caused under the comprehensive impact of complex load condition, temperature stress and mechanical stress of coke drums, which is a serious threat to safety production. The development and application of coke drum structural health monitoring system ensures the healthy operation of the equipment, and will effectively cope with the increasing long-term operation requirements of refining and chemical enterprises. Based on the stress monitoring data of the key parts of the coke drum, as well as the operating pressure and temperature data, this paper analyzes the characteristics of coke drum structure monitoring data and the causes of circumferential weld cracking of coke drum structure. The residual life of the monitored structure is evaluated by using the improved rain flow counting statistical method and miner fatigue cumulative damage theory. Finally, the contribution rate of different process sections of coke drum to its structural damage is analyzed. This study provides a reference for structural health monitoring and operation process optimization of coke drum.
EXPERIMENTAL INVESTIGATION ON A NOVEL OSSEOINTEGRATED IMPLANT STABILITY ASSESSMENT USING ON VIBRATION ANALYSIS
Authors: LU SHOUXUN , VIEN BENJAMIN STEVEN , RUSS MATTHIAS , FITZGERALD MARK , CHIU WING KONG
Published: October 2022

Osseointegrated prostheses are widely used as the treatment for femur amputation. However, this technique requires sufficient implant stability before and during the rehabilitation period to mitigate the risk of implant breakage and loosening. Hence, reliable assessment methods for the osseointegration process are essential to ensure initial and long-term implant stability. This paper aims to investigate a vibration analysis method with a novel implant design, which focuses on the analysis of the dynamic response of the femur-implant system during the simulated osseointegration process. The paper also proposes a concept of using normalized energy difference to formulate an energy index (E-index). A 133mm-long amputated artificial femur model was constrained at the proximal end with a customized clamp. The epoxy adhesives were applied at the interface between the aforementioned femur and implant to simulate the change in stiffness in mimicking the osseointegration process. A two-unidirectionalsensor setup attached to the bottom of the implant was used to record the dynamic response stimulated by an impact hammer. The results show a significant change in magnitude of the cross-spectrum during the osseointegration processes. The resonance modes in cross-spectrum for the frequency above 1000Hz are hard to distinguish suggested that the vibration of the system being hindered by the high dampening effect of the adhesive before the initial bonding of the adhesive at 300s. The plot of E-index shows a clear correlation that the E-index provided a potential quantitative approach for monitoring the stages of osseointegration. These findings highlight the feasibility of using the vibration analysis technique and E-index to quantitatively monitor the osseointegration process for future improvement on the efficiency of human health monitoring and patient rehabilitation.
DETECTING BENDING AND IMPACT EVENTS IN A FIBER OPTIC CABLE USING DISTRIBUTED ACOUSTIC SENSING TO ASSESS POTENTIAL OFFSHORE POWER CABLE DAMGES
Authors: RYVERS JASPER , CALLEWAERT MANLY , LOCCUFIER MIA , WAELE WIM DE
Published: October 2022

A key vulnerability of offshore energy production facilities are submarine power cables. Monitoring a power cable during its entire lifetime is a strategy to minimize critical damages. Submarine power cables contain fiber optic cables that can be used for monitoring purposes. In this paper we show that a recent fiber optic sensing technique (CP-ΦOTDR) [11] is capable of detecting bending and impact events in a fiber optic cable. It does so with a limited reproducibility however, which for impact events cannot be solely explained by the variability of the impact force. There is a slight signature present for impact events: identical impact force events correlate more than events belonging to non-identical forces. This work is a first step in developing a monitoring tool to help assess the severity of power cable damages due to incident impacts and critical bending states.
ASSESSING THE INFORMATION CONTENT OF DATASETS FOR STRUCTURAL HEALTH MONITORING
Authors: WICKRAMARACHCHI, CHANDULA T. , JIANG XIAOFEI , CROSS ELIZABETH J. , WORDEN KEITH
Published: October 2022

Data-based SHM is highly dependent on the quality of the training data needed for machine learning algorithms. In many cases of engineering interest, data can be scarce, and this is a problem. However, in some cases, data are abundant and can create a computational burden. In data-rich situations, it is often desirable to select the subset(s) of the data which are of highest value (in some sense) for the problem of interest. In this paper, ‘value’ is interpreted in terms of information content, and entropy is used a measure of that content in order to condense training data without compromising useful information. Using the minimum covariance determinant, the dataset is first separated using inclusive outlier analysis. The entropies of the separated datasets are then assessed using parametric and nonparametric density estimators to identify the subset of data carrying most information. The Z24-Bridge dataset is used here to illustrate the idea, where the entropy values indicate that the subset containing data from environmental variations and damage is most rich in information. This subset was made up of half of the entire dataset, suggesting that it is possible to significantly reduce the amount of training data for an SHM algorithm whilst retaining the required information for analysis.
Alfonso X: estudios sobre la lengua de los textos alfonsíes
Authors: Cano Aguilar Rafael
Published: October 2022

En este volumen se recogen diversos trabajos elaborados sobre la lengua utilizada en los textos alfonsíes. Se ha prestado especial atención a los aspectos sintácticos y de construcción del discurso, los menos tenidos en cuenta hasta el momento en el estudio de la obra atribuida al Rey Sabio. Entre estos aspectos destacan los que tienen que ver con la cohesión textual lograda por medio de la utilización de procedimientos de conexión explícita (nexos, marcadores, etc.), y los que se refieren a los modos de engarzar las secuencias textuales (según la terminología gramatical, parataxis vs. hipotaxis). También se analizan en el trabajo otras cuestiones. tales como la conciencia manifestada por los redactores alfonsíes sobre los modelos lingüísticos que han de tenerse en cuenta en la producción de enunciados, así como las denominaciones utilizadas para la lengua que utilizan ("castellano", "romance" y otras). Finalmente, se hace un repaso de carácter historiográfico sobre los modos en que la lengua de los textos alfonsíes, en particular la "Historia de España" ha sido analizada en la Filología y Lingüística de ámbito hispánico.
Buddyzm w Indiach. Ideowa rewolucja czy kontynuacja?
Authors: Jakubczak Krzysztof
Published: October 2022

The author intends to explicate the content of the Buddhist experience. The first part of the text discusses the cognitive and existential aspects of Buddhist experience. The second part deals with some historical issues of Indian Buddhism. In the third part the author strives to indicate this moment in Buddhist thought, embedded in the early texts of the Indian period, in which there is a fundamental split in the way of expressing the original intuition of the Buddhist experience of existence. In the author’s opinion, all subsequent Buddhist ontological disputes originated in the discrepancies already revealed in the texts of the early canons, especially in the Pāli and Sanskrit versions of the Discourse to Kātyāyana.
Nieprawda ważniejsza od prawdy – buddyzm chan w oczach jego współczesnych badaczy
Authors: Zamorski Jakub
Published: October 2022

The present paper aims to present an overview of major ideas, practices and cultural manifestations of Chinese Chan Buddhism from the perspective of contemporary academic literature on this subject. The first part describes the background of Chan’s emergence as the meditative tradition of Sinitic Buddhism in the first millennium AD and discusses some key doctrinal and practical tenets of this tradition emphasized by the pre- -modern Chan authors. The second part presents major literary genres associated with Chan and their role in creating a personal role model of an enlightened Chan master. The third and final part attempts to situate Chan Buddhism within a larger context of the intellectual history of early modern and contemporary China; it points out the impact of Chan ideas and rhetoric on various doctrines and practices of Pure Land Buddhism, Neoconfucianism and Daoism and discusses the patterns of transformation which Chan itself underwent in the 20th century.
Nuevas tendencias competenciales en el ámbito profesional del derecho: un análisis de los portales de empleo
Authors: Lasaga Millet Olga , Barraycoa Martínez Javier , Cirera Catalan Raimon
Published: October 2022

El presente estudio tiene por objeto analizar las competencias profesionales demandadas en las ofertas publicadas en los portales de trabajo en función del área de especialización legal. Para ello se ha utilizado la plataforma de big data Job Market Insights, que permite analizar el mercado de trabajo y se ha extraído una muestra de conveniencia no probabilística total de 368 ofertas, en el período comprendido entre el 1 de septiembre de 2020 y el 31 de mayo de 2021. En el proceso de tratamiento de los datos se ha categorizado las competencias demandadas y el área de especialización.
Los datos obtenidos han sido tratados mediante la versión 27 del programa SPSS Statistics de IBM. Primero, se han calculado los estadísticos descriptivos univariantes de cada una de las variables escogidas para el análisis. Seguidamente, se han definido diversos conjuntos de respuestas múltiples y codificado como variables dicotómicas para poder presentar un análisis descriptivo compacto de la muestra. Se ha realizado un análisis de correspondencias múltiples para distinguir la existencia de patrones y relaciones de interdependencia entre variables.
Los resultados del análisis permiten detectar las disonancias entre las competencias que aparecen en los planes de estudio respecto de las demandadas en las ofertas de trabajo. Asimismo se descubren nuevas perspectivas del comportamiento competencial de la profesión y se extraen conclusiones y reflexiones para mejorar la empleabilidad de estudiantes y egresados en Derecho.
La importancia de los pactos educativos. Obstáculos para su consecución
Authors: Martínez-Candado Julia
Published: October 2022

El pacto escolar alcanzado en el artículo 27 de la Constitución Española de 1978 representó un hito en el equilibrio entre dos modelos educativos claramente enfrentados. Sin embargo, la fragilidad del acuerdo se evidenció tempranamente, incluso en el mismo debate del texto constitucional, en el que se solicitaba la retirada de la primera Ley que regularía la educación conforme al marco fijado por el texto constitucional, la LOECE. Se había alcanzado el consenso básico, pero no el consenso político, y se abría paso a un desarrollo normativo que evidenciaría que el modelo educativo se balancea dependiendo del programa político. Desde entonces, y a pesar de la sucesión de leyes, la idea de un pacto educativo no ha estado ausente. Pero, su consecución se enfrenta a una serie de obstáculos que, hasta el momento, lo han hecho imposible.
En este artículo, se analiza la necesidad de un pacto en materia educativa y se revisan los principales obstáculos ideológicos que impiden su consecución.
Cumplimiento cooperativo, gobernanza fiscal y derechos y garantías de los contribuyente
Authors: Carrasco Parrilla Pedro José
Published: October 2022

Dentro del modelo de cumplimiento cooperativo de las obligaciones tributarias, se trata de determinar si en la actual configuración de la Gobernanza fiscal priman más los derechos y garantías de los contribuyentes frente a las obligaciones impuestas a los mismos, sobre todo si tenemos en cuenta las nuevas obligaciones derivadas de la transposición de la DAC6 en el ordenamiento jurídico español. En aras de intentar equilibrar los derechos y obligaciones, dentro de una relación cooperativa, basada en la transparencia y la confianza mutua, sería deseable arbitrar algún mecanismo que tenga en cuenta el esfuerzo de los obligados tributarios, introduciendo modificaciones normativas que permitan excluir el dolo, o incorporar ciertos incentivos a las entidades que implementen modelos eficientes de cumplimiento cooperativo, constituyendo una propuesta de derecho comparado la ley francesa que reconoce el derecho a la regularización “en caso de error”, junto con la propuesta en el año 2022 del Consejo para la Defensa del contribuyente sobre la incorporación del “derecho al error” en el ordenamiento tributario español. También se aboga por reforzar los instrumentos de información y asistencia a los obligados a comunicar los mecanismos transfronterizos sujetos a comunicación, sobre todo en el caso de las respuestas a consultas tributarias, acuerdos previos de valoración o la necesaria publicación de guías interpretativas, que otorgarán sin duda una mayor seguridad jurídica al dotar de una mayor uniformidad y transparencia a los criterios de interpretación y aplicación de la norma.
Máxime cuando, en un contexto en el que la relación cooperativa no está basada en la idea de relación de poder entre Administración y obligados tributarios sino en la confianza mutua y la transparencia, ésta debe manifestarse también por el lado de la Administración, que además de transparente, debe fomentar las actuaciones preventivas de la conflictividad, junto con labores de asistencia y colaboración.
Educación fiscal y desarrollo de una ética y cumplimiento tributario
Authors: Masbernat Patricio
Published: October 2022

El presente artículo aborda una triada de asuntos. Por una parte, la ética tributaria, que se fundamenta en la democracia deliberativa y los principios de justicia social. El cumplimiento tributario, que no solo tiene su base en la obligación legal, sino también en el compromiso de las personas con su propia comunidad y en el rol de la ciudadanía. Ambos extremos pueden ser fortalecidos por la educación en materia tributaria, cuya finalidad no es sólo el adecuado funcionamiento del sistema legal tributario sino también de las instituciones públicas en general.
Long-range interaction between solitons in strongly nonlocal nonlinear media with oscillatory response
Authors: Zhang Daoqing , Zhong Lanhua
Published: October 2022

The long-range interaction between two identical solitons in strongly nonlocal nonlinear media with the sine-oscillation response function is studied. It is found that the two solitons may attract each other, repel each other, or keep in parallel in the initial stage. The behavior of the soliton interactions depends periodically on the separation between solitons; it is essentially controlled by the superposition of the periodic light-induced nonlinear refractive index. The different versions of the soliton interactions can be interchanged by adjusting the separation between solitons.
End-to-end deep learning of geometric shaping for unamplified coherent systems
Authors: Oliveira B. M. , Neves M. S. , Guiomar F. P. , Medeiros M. C. R. , Monteiro P. P.
Published: October 2022

With the increasing data rate requirements on short-reach links, the recent standardization of unamplified coherent optical systems is paving the way for a cost and power-effective solution, targeting a massive deployment in the near future. However, unamplified systems are introducing new challenges. Particularly, the performance is highly dependent on the peak-to-average power ratio (PAPR) of the transmitted signal, which puts at question the use of the typical constellation formats. In this work, we use an end-to-end deep learning framework to optimize the geometry of different constellation sizes, ranging from 8- to 128-ary constellations. In general, it is shown that the performance of these systems is maximized with constellations whose outer symbols are disposed in a square shape, owing to the minimization of the real-valued PAPR. Following this premise, we experimentally demonstrate that odd-bit constellations can be significantly optimized for unamplified coherent links, achieving power budget gains in the range of 0.5–3 dB through the geometric optimization of 8-, 32- and 128-ary constellations.