bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrochemical Study of Bismuth Heavy Metals Using the Cyclic Voltammetry Method in Anti-Protozoal
Authors: alkhawaldeh ahmad
Published: January 2023

Bismuth oxides are well-known electro-catalysts in fuel cells systems; they are usually used as anodic materials for the oxidation of low molecular weight alcohols. The utilization of BiO2 and MnO2 as catalysts in the pharmaceutical analysis is analytical method for the determination of heavy metal antibacterial agents in Pharmaceutical Dosage form is developed. The method is based on the voltammetric determination of heavy metal using Bidified platinum electrode by Bismuth oxide. The two components are oxidized at the Bidified electrode surface with the development of current that is linearly proportional to their concentrations in the range of 7.04*10-7- 1*10-3 M heavy metal. The oxidation reaction of the two components is pH-dependent, in which the buffer used is Britton-Robinson at pH = 7.00 where maximum peak current and maximum peak separation is obtained. The regression factors obtained from the calibration curves are 0.9812. The method of analysis was validated, where the limit of detection (LOD) and the limit of quantitation (LOQ) were calculated to be 1.44*10-4 M, 4.36*10-4 M and 1.27*10-4 M, 3.84*10-4 M respectively, the percentage recovery of both components was also calculated to 77 % for heavy metal.
Partisipasi Masyarakat Dalam Manajemen Bencana Untuk Pembangunan Masyarakat Berkelanjutan
Authors: KINANTHI RESTI
Published: January 2023

Indonesia is a country that has various disaster risks, including geological, hydrometeorological, and social disasters. Community participation is very necessary in reducing disaster risk, both before a disaster occurs, during a disaster, and after a disaster occurs. The process of community development cannot be separated from the existence of various disturbances, one of which is caused by a disaster. The development achievements that have been made cannot be avoided from the risk of disaster, the loss of stability in the social system can also hinder the achievement of sustainable community development.

Community development and disaster risk reduction have in common, among others, reducing community vulnerability and empowering communities to increase capacity and disaster preparedness. Integrating community development with the active participation of the community is the same as reducing disaster risks that may be experienced by the community. Community capacities and vulnerabilities are analyzed and incorporated into project design to make them more responsive to the development context of disaster-affected communities.
The Socialization Of Perma Number 5 Of 2019 Concerning Guidelines To Address Applications For Marriage Dispensation As An Effort To Prevent Child Marriage In Boyolali
Authors: Ngazizah Inna Fauziatal
Published: January 2023

The purpose of the stipulation of Supreme Court Regulation Number 5 of 2019 concerning Guidelines for Adjudicating Applications for Marriage Dispensation is to overcome problems regarding applications for marriage dispensations in the Religious Courts. The reality that is happening in society is actually increasing. Based on this, this activity aims to determine the extent of public understanding about the impoartance of the marriage age limit, and to prevent child marriage in Boyolali through socialization of Supreme Court Regulation Number 5 concerning Guidelines for Adjudicating Applications for Marriage Dispensation. The analytical methodology used in this study is juridical-sociological with complementary data which is the distribution of information through interviews with informants through several question indicators described in the discussion. The results of this study indicate that people do not fully understand the importance of the age limit for marriage. So that the socialization of Supreme Court Regulation Number 5 of 2019 concerning Guidelines for Adjudicating Applications for Marriage Dispensation is necessary to suppress child marriage rates for Boyolali.

 
The Development and Effectiveness of Web Based Media Provider Costume by User to Improve Elementary School Students’ Understanding
Authors: Nurdyansyah Nurdyansyah , Arifin Moch. Bahak Udin By , Rosid Mochamad Alfan , Rais Pandi
Published: January 2023

The problem at elementary schools was the use of media that was not in accordance with the context and needs of teachers and students in the classroom through instructional design. The purpose of this study was to develop and evaluate the effectiveness of a web-based media provider costume by the user (Web-MPCU) to improve students’ understanding of the material and test the effectiveness of its application through instructional design at elementary schools. The development model used was Huang's instructional design development model. The results of the study show that instructional design provided information needs that were appropriate to the problems of the school context and resolves them by developing and implementing the Web-MPCU. The results of the development and evaluation of the use of the Web-MPCU show that it was valid, feasible, and effectively applied to improve understanding of the material in elementary schools. The effectiveness of the use of the Web-MPCU was also shown from the ease with which the teacher asks and analyzes the media needs of his students.
Pethik Laut Tradition as a Ritual of Repelling Bala (Study of Sociology Disaster)
Authors: Rahma Rosselina Mulya
Published: January 2023

Indonesia is an archipelagic country that is famous for its ethnic, racial, religious and cultural diversity. This diversity is widespread in every area from Sabang to Merauke. The diversity of ethnicity, race, religion, and culture is in line with the many traditions that exist in every region in Indonesia. Each region has traditions and rituals that have their own meaning and purpose. One of them is the sea picking tradition carried out by the Muncar community, Banyuwangi Regency. This tradition has its own meaning and purpose for the people around Muncar. This study uses a qualitative research method with a case study approach. This study aims to analyze the Petik Laut tradition with the perspective of the sociology of disaster. The results of this study indicate that the Picking Laut tradition carried out by the Muncar community is a ritual to ask for safety for fishermen to avoid disasters while looking for fish in the sea
Understanding Social Structure and Social Relations in Differentiated Learning in Driving School Programs
Authors: Martanti Fitria , Hardati Puji
Published: January 2023

The purpose of this study was to determine the social structure and social relations in differentiated learning and to find out the obstacles in the preparation of student learning profiles in the driving school program. This is one of the interesting things to study because the driving school program is a new program and uses the principle of differentiated learning. This study uses qualitative methods with data collection techniques using interview, documentation and observation techniques. Based on the results of the study, it can be seen that the social structure of the community is mostly underprivileged families and the education of parents is mostly elementary school graduates. The social relations of students from the research results can be seen from student relations both at school and at home. The obstacles in the implementation of the preparation of student learning profiles are the ability of teachers to identify the needs of students is limited, parents are not able to understand the condition of students such as the physical condition of students who encourage students to use aids in the learning process. Another obstacle faced is the lack of implementation of interest aptitude tests to identify problems faced by students, students' academic abilities, and students' potential in various fields. On the other hand, the student learning profile instrument demands complex identification from both teachers and parents.

Keywords: Social Structure, Social Relations, Differentiation, Sekolah Penggerak
The Effect of Trust on Organizational Citizenship Behavior (OCB) on Officers at Class IIB Kudus State Detention Center
Authors: Halilintar Ilham Saputra , Kusmiyanti Kusmiyanti
Published: January 2023

OCB is the behavior of organizational members who provide voluntary assistance outside the job description which is very beneficial for the organization because it can increase effectiveness and efficiency in the organization. Many factors can affect OCB, one of which is trust. This study aims to examine the effect of trust on Organizational Citizenship Behaviour (OCB) on officers at Class IIB Kudus State Detention Center. This study uses quantitative methods with research subjects all officers at Class IIB Kudus State Detention Center. The purpose of this study was to determine how much influence trust has on Organization Citizenship Behavior on officers. The sample in this study amounted to 46 officers obtained with the saturated sample technique. The data in this study were obtained through distributing questionnaires and using data analysis with the simple linear regression analysis method and processed in the SPSS program. The research procedures tested include validity testing, reliability testing, normality testing and research hypothesis testing. The results of the simultaneous test (f) and partial test (t) found that the value of f arithmetic was greater than f table (10.401> 4.06) and t arithmetic was greater than t table (3.225 > 2.015). This shows that there is an influence of the Trust variable on the Organizational Citizenship Behavior (OCB) variable and there is a positive and significant relationship between the two variables. This means that trust has a positive influence on OCB on officers at Class IIB Kudus State Detention Center.
Implementation of Islamic Spiritual Guidance in Growing Self-Acceptance of Cancer Patients
Authors: Kibtyah Maryatul , Nisa' Khoirun , Maulana Khabib Akbar
Published: January 2023

Cancer sufferers need Islamic spiritual guidance. Islamic spiritual guidance has received attention from religious institutions, namely the Indonesian Zakat Initiative Patient Shelter. This study aims to determine the implementation of Islamic spiritual guidance in growing self-acceptance of cancer patients. The type of this research method is using descriptive qualitative and psychological approach. Data collection techniques in this study used participant observation, unstructured interviews and documentation. The results of this study indicate that first, the implementation of Islamic spiritual guidance has been proven to provide solutions to the problems experienced by cancer sufferers in growing self-acceptance, in the form of: direct methods by listening and giving advice face to face, the material presented is related to belief in the help of Allah SWT, life motivation and wisdom behind illness. Second, cancer sufferers who have low self-acceptance are characterized by frequent crying, difficulty controlling their emotions, not accepting the situation they are suffering from. After receiving Islamic spiritual guidance, cancer sufferers are able to be positive about themselves, willing to accept their good and bad qualities, and have a positive attitude towards their past so that they can be said to experience growth in self-acceptance in an optimal direction.
Using of Speech Trainer in the Learning Guidance of Children with the Deaf in SLB Pancaran Iman
Authors: Kusnawan Aep , Muslimah Sitta Resmiati , Karmilah Riska
Published: January 2023

Every citizen has the same right to obtain education. This opportunity also includes the Deaf. Deaf are those who lose hearing where a person cannot perceive various stimuli through the sense of hearing. Due to a lack of hearing, Deaf children need special tutoring methods. This study reveals the use of one of the methods referred to as the Speech Trainer method. This research is a qualitative descriptive field research to reveal the technique of using Speech Trainer in Guidance for Deaf Children at SLB Pancaran Iman. The results showed that the use of the Speech Trainer as a tool was deliberately designed for deaf people with a high level of sensitivity. The presence of a speech trainer is assisted by animations that demonstrate the movement of breathing and pronunciation exercises. The animation movement is repeated according to the will of the deaf child. To control the words or sentences produced, use a voice recognition that can judge whether or not the sound produced by a child with hearing impairment is correct. With the use of the Speech Trainer, the deaf students are helped in the communication process of their tutoring.
The Effectiveness of Guidance and Counseling Services in Schools in the New Normal Era
Authors: Masturin Masturin , Nafi' Ahmad
Published: January 2023

The new normal era resulted in paralysis in various sectors, such as education, health, and economics. The social distancing policy has also brought about the closure of schools by implementing learning from home or online. Thus, various problems arise, experienced by teachers, students, and even guardians of students. In addition, guidance and counseling are also impacted by this policy. For this reason, this study aims to describe the application of guidance and counseling services in the new normal era and see how effective the services provided are. This type of research used descriptive qualitative research and focused on phenomenological studies. The research subjects were two guidance and counseling teachers and two students. Observation, interview, and documentation techniques were employed as data collection techniques. To determine the data validity, the researchers used technical and source triangulations. The results of this study revealed that the guidance and counseling services run were not effective. It was because several problems were experienced by schools, such as online learning policies, the lack of a ratio of the number of guidance and counseling teachers to the number of students, and the lack of socialization about the role of guidance and counseling.
Improving Self Esteem of Students of Islamic Counseling Guidance Study Program Through Training of Trainers (ToT) at IAI Darussalam Blokagung Banyuwangi
Authors: Al Musafiri M Rizqon , Muarif Ahmad Syamsul , Sa'diah Halimatus
Published: January 2023

The need for prospective graduates of Islamic guidance and counseling to work is to have an awareness of their potential, abilities and self-awareness. This can be seen from the students' self-esteem. However, the situation shows that some students show low self-esteem. Self-esteem needs to be increased through the Training of Trainers (ToT) Super Student. This training aims to motivate individuals to make dreams come true. This study measures the success of the Training of Trainer (ToT) Super Student for increasing students' Self Esteem. One Group Pretest and Posttest designs were used to measure the self-esteem of the Training of Trainer treatment students. The result is an average pretest of 97.98. The average value of the posttest score calculation is 142.68 and the standard deviation is 9,127 after receiving the Training of Trainers (ToT) Super Student. This shows that Training of Trainers (ToT) Super Student is effective in increasing the Self-esteem of Students of the Islamic Guidance and Counseling Study Program IAI Darussalam Blokagung.
Islamic Spirituality in Psychological Well-Being in Adolescents
Authors: Mashurin Mashurin , Wangid Muhammad Nur , Fadkhurosi Adnan
Published: January 2023

Islamic Spirituality in Psychological Well-Being in Adolescents. Adolescents who have psychological well-being mean that they have a prosperous soul. A prosperous soul describes how positively a teenager lives and carries out his.her psychological functions. The objective of this study was to determine Islamic spirituality in psychological well-being in adolescents. This study used a quantitative approach. The population in this study were all teenagers in Nologaten, Sleman, Yogyakarta totaling 135 people. The sampling technique used random sampling to obtain a total sample of 103 people. The data collection technique used a scale that has been tested for validity and reliability. The data analysis technique was used to answer the hypothesis is the Product Moment correlation of Karl Person. The results of this study indicate that: (1) there is a relationship between Islamic spirituality in psychological well-being in adolescents, as evidenced by the value of r count > r table (0.653> 0.195) and a significance value of 0.000 <0.05; and (2) The influence of Islamic spirituality on the psychological well-being of adolescents is 0.564%
Guidance Collaborative Study for Children with special needs
Authors: Mujahid Imam
Published: January 2023

This study aims to describe the form of collaboration between parents and counselor in learning services for children with special needs. This research is a case study on children with special needs with ADHD and Autism. The resource persons in this study were parents, counselor and peers of children with special needs. Qualitative data analysis technique was carried out inductively with Miles Huberman's interactive model analysis, which began with collecting data through observation notes, and interviews with 2 ADHD children and 2 Autism children. The results of the study indicate that the collaboration between parents and counselor can increase the enthusiasm for learning for children with special needs so that their learning development can run optimally. In this collaboration pattern, several different collaboration patterns were found in research on crew members as objects. The form of collaboration is virtual, face-to-face and carried out with both modes. This form of learning service for ABK is carried out in the form of collaborative guidance between parents and counselor internally and externally.
Fostering an Entrepreneurial Spirit Through Islamic Career Guidance Services Based on Noble Purpose
Authors: Peristiwo Hadi , Nida Fatma Laili Khairun
Published: January 2023

Islamic career guidance for students is an effort to provide assistance in preparing for the world of work, choosing jobs or certain professional positions with Islamic principles. The urgency of career guidance for students is motivated by the number of students who became unemployed after they graduated from college because they were still oriented to the ideals to find jobs, not to create jobs or entrepreneurship. Noble purpose or noble ideals in entrepreneurship will not only move students awareness to benefit themselves, but beyond the target to be able to spur on a greater benefit for many people and the surrounding environment. The purpose of this study is to find out how the implementation of Islamic career guidance in fostering the spirit of entrepreneurial spirit among students. This type of research is a field research with qualitative analysis with data collection techniques using observations, interviews and documentation. The results of this study indicate : First, the process of Islamic career guidance services is carried out comprehensively ranging from strengthening to ethics and work ethic. Second, the impact of Islamic career guidance services using noble purpose fosters spiritual values in students in entrepreneurs itself but also for others in the form of creating jobs and initiating the people around them in order to get a better life expectancy.
Reconstruction of a Chronic and Retracted Distal Adductor Longus Tear Using Achilles Allograft
Authors: Ahlquist Seth , Barnes James , Eranki Anirudh , Hame Sharon L.
Published: January 2023

Update

This article was updated on February 2, 2023, because of a previous error. One of the author's degrees was incorrect. Anirudh Eranki's degree was listed as BS, but this author did not have a degree at time of publication.

An erratum (JBJS Case Connect. 2023;13[1]:e22.00522ER) has been published for this article.

Case:

We present an active-duty male service member in his second decade of life who presented with a painful medial thigh mass and functional limitations 1 year after a football injury and was diagnosed with a chronic distal adductor longus tendon tear. He was successfully treated with a novel reconstruction technique using Achilles allograft.

Conclusion:

Chronic distal adductor longus tendon tears are a rare condition that can be successfully treated with an Achilles allograft reconstruction method in high-demand, active individuals.
THE BISON AND THE BLOW FLY: USING PUPARIA OF THE BLACK BLOW FLY (PHORMIA REGINA: DIPTERA, CALLIPHORIDAE) TO CONSTRAIN THE SEASON OF DEATH AND TAPHONOMIC HISTORY OF AN EARLY HISTORIC-AGE BISON, CARSON CITY, NEVADA, USA
Authors: ROWLAND STEPHEN M. , WHITWORTH TERRY L. , JONES MICHELE , DOOLEY JOHN , CHAMEROY ERIC , GORDON THOMAS
Published: January 2023

We report the occurrence of abundant dipteran puparia of Phormia regina, the black blow fly, in association with an early historic-age bison skeleton excavated near Carson City, Nevada. Cut marks on some of the bones indicate that the bison was butchered and probably skinned by humans. Radiocarbon dating provides two possible age intervals for the death of the bison: (1) latest seventeenth to early eighteenth century or (2) early nineteenth to early twentieth century; we consider the more recent age to be more plausible. The purpose of this study is to explore how the presence of puparia of this well-studied, necrophagous fly species can be used to help constrain the season of death and inform the interpretation of the taphonomic history of the bison.

The life cycle of P. regina requires a minimum of 8.8 days within a temperature range of 14°C to 35°C, so the bison carcass must have been exposed to the air for at least that long within that temperature range. However, of the thousands of recovered puparia, 35% remain closed and did not produce adult flies; of this cohort, only a tiny percentage exhibit small exit holes attributable to parasitoid wasps. Cold temperatures, and not parasitoid wasps, are the most probable cause of the high pupal mortality. Climate data for the region, along with P. regina temperature constraints and streamflow and flooding records for the Carson River watershed, indicate that the bison died and was colonized by black blow flies in the spring, when night-time temperatures were low. A short time later the skinned and butchered skeleton was buried by floodplain sediments. Blow fly puparia can contribute useful information for the taphonomic analysis of vertebrate fossil sites.
THE TAPHONOMIC CHARACTER, OCCURRENCE, AND PERSISTENCE OF UPPER PERMIAN–LOWER TRIASSIC PLANT ASSEMBLAGES IN THE MID-PALEOLATITUDES, BOGDA MOUNTAINS, WESTERN CHINA
Authors: GASTALDO ROBERT A. , WAN MINGLI , YANG WAN
Published: January 2023

The Bogda Mountains, Xianjiang Uygur Autonomous Region, western China, expose an uppermost Permian–Lower Triassic succession of fully continental strata deposited across three graben (half graben) structures in the mid-paleolatitudes of Pangea. A cyclostratigraphy scheme developed for the succession is subdivided into three low-order cycles (Wutonggou, Jiucaiyuan, Shaofanggou). Low-order cycles are partitioned into 1838 high-order cycles based on repetitive environmental changes, and their plant taphonomic character is assessed in > 4700 m of high-resolution, measured sections distributed across ∼ 100 km. Four taphonomic assemblages are represented by: permineralized wood (both autochthonous and allochthonous), megafloral adpressions (?parautochthonous and allochthonous) identifiable to systematic affinity, unidentifiable (allochthonous) phytoclasts concentrated or disseminated on bedding, and (autochthonous) rooting structures of various configurations (carbon films to rhizoconcretions). Their temporal and spatial occurrences vary across the study area and are dependent on the array of depositional environments exposed in any particular locality.

Similar to paleobotanical results in other fully continental basins, megafloral elements are rarely encountered. Both wood (erect permineralized stumps and prostrate logs) and adpressions are found in < 2% of meandering river and limnic cycles, where sediment accumulated under semi-arid to humid conditions. The absence of such assemblages in river-and-lake deposits is more likely related to physical or geographical factors than it is to an absence of organic-matter contribution. With such a low frequency, no predictable pattern or trend to their occurrence can be determined. This is also true for any horizon in which rooting structures are preserved, although paleosols occur in all or parts of high-order cycles developed under arid to humid conditions. Physical rooting structures are encountered in only 23% of these and are not preserved equally across space and time. Allochthonous phytoclasts are the most common taphonomic assemblage, preserved in association with micaceous minerals on bedding in fine-grained lithofacies. The consistency of phytoclast assemblages throughout the succession is empirical evidence for the presence of riparian vegetation during a time when models propose the catastrophic demise of land plants, and does not support an interpretation of vegetational demise followed by long-term recovery across the crisis interval in this basin. These mesofossil and microfossil (palynological) assemblages offer the best opportunity to understand the effects of the crisis on the base of terrestrial ecosystems.
Revisión de revisiones sobre la eficacia de los tratamientos psicológicos para adolescentes con trastorno de la personalidad límite
Authors: Navarro Haro María V.
Published: January 2023

La literatura científica señala que es importante llevar a cabo una intervención psicológica temprana en el trastorno de la personalidad límite (TPL) debido a que en la adolescencia es cuando se observa un mayor auge de los síntomas graves. Sin embargo, existe poca literatura científica sobre qué tratamientos psicológicos son más eficaces para esta población. El objetivo de este trabajo es realizar una revisión de revisiones sobre los datos de eficacia de los tratamientos psicológicos para adolescentes con rasgos o diagnóstico de TPL o desregulación emocional. Se seleccionaron revisiones que evaluaran la eficacia de tratamientos psicológicos en adolescentes (entre 12 y 19 años) con esta problemática. Se realizó una búsqueda de literatura científica en diversas bases de datos (Web of Science, PsycInfo, Pubmed, Dialnet) y se incluyeron un total de 5 revisiones. Resultados: La Terapia Dialéctica Comportamental para adolescentes (DBT-A) y la Terapia Basada en la Mentalización para adolescentes (MBT-A) han demostrado su eficacia para reducir la ideación suicida, los síntomas de TPL, los niveles de ansiedad y depresión, así como mejorar la adaptación social y la calidad de vida después de la intervención. Sin embargo, algunas revisiones sugieren que la MBT-A podría no ser tan efectiva debido a las altas tasas de abandonos. Las intervenciones psicológicas con más evidencia consiguen reducir los síntomas más graves y mejorar la calidad de vida de los adolescentes con este problema. Es fundamental intervenir lo antes posible, lo que ayudará a prevenir el desarrollo y cronicidad de un trastorno grave y difícil de tratar.
Avatar-based patient monitoring for intensive care units improves information transfer, diagnostic confidence and decreases perceived workload- a computer- based, multicentre comparison study
Authors: Bergauer Lisa , Braun Julia , Roche Tadzio Raoul , Meybohm Patrick , Hottenrott Sebastian , Zacharowski Kai , Raimann Florian Jürgen , Rivas Eva , López-Baamonde Manuel , Ganter Michael Thomas , Nöthiger Christoph Beat , Spahn Donat R. , Tscholl David Werner , Akbas Samira
Published: January 2023

Background
Patient monitoring is the foundation of intensive care. High workload and information overload can impair situation awareness of staff, thus leading to loss of important information about patient's conditions. To facilitate mental processing of patient monitoring data, we developed the Visual-Patient-avatar Intensive Care Unit (ICU), a virtual patient model animated from vital sign and patient installation data. It incorporates user-centered design principles to foster situation awareness. This study investigated the avatar's effects on information transfer measured by performance, diagnostic confidence and perceived workload.
Methods
This study compared Visual-Patient-avatar ICU and conventional monitor modality. We recruited 25 nurses and 25 physicians from five centers. The participants completed an equal number of scenarios in both modalities. Information transfer, as the primary outcome was defined as correctly assessed vital signs and installations. Secondary outcomes included diagnostic confidence and perceived workload. For analysis, we used mixed models and matched odds ratios.
Results
Comparing 250 within-subject cases revealed that Visual-Patient-avatar ICU led to a higher rate of correctly assessed vital signs and installations (rate ratio (RR), 1.25; 95% CI, 1.19–1.31; P < 0.001), strengthened diagnostic confidence (odds ratio (OR), 3.32; 95% CI, 2.15–5.11, P < 0.001) and lowered perceived workload (Coefficient, − 7.62; 95% CI, − 9.17- −6.07; P < 0.001) than conventional modality.
Conclusion
Using Visual-Patient-avatar ICU, participants retrieved more information with higher diagnostic confidence and lower perceived workload compared to the current industry standard.
Blockchain Technology in Healthcare within the Global South: Mapping the Area and Developing a Research Scenario
Authors: El-Gazzar Rania , Watat Josue Kuika , Agbozo Ebenezer
Published: January 2023

Africa's steady technological expansion, coupled with the advent of pandemics that cause severe public health challenges, underscores the critical need to build resilient healthcare systems. This article outlines the potential of blockchain within African healthcare and transformations it has triggered. This research fosters scientific and practical thinking for developing systems that respond to contextual exigencies. Furthermore, we conduct a scientific assessment to: 1) consolidate existing research on Blockchain within healthcare in Africa; 2) comprehend technology and theory commonalities within research; 3) outline use cases of this disruptive technology, 4) identify areas of consideration in the broad African healthcare sector, while identifying scientific lacunae to develop new theoretical guidelines. Our multi-method approach fulfills appeals by emerging literature regarding novel methodological framework development for interpreting phenomena, and comprehending global trends. Consequently, our research impacts academia and industry, primarily in the development of a legal and regulatory framework for the integration of blockchain technology into African healthcare.
The informal way to success or failure? Findings from a comparative case study on video consultation training and implementation in two Danish hospitals
Authors: Eriksen Susanne , Dahler Anne Marie , Øye Christine
Published: January 2023

Background This study evaluated an attempt to implement video consultations through a novel approach to telehealth training and implementation in two middle-sized hospitals in Denmark. Three units tested the novel approach along with a regional decision to strengthen multidisciplinary and cross-sectoral collaboration through technology to improve service delivery by making the process more coherent, as well as to save time and resources. This study aims to investigate what contextual factors enable workplace learning, skills acquisition, and utilization of new digital skills to use video consultations in workplace practice. Methods This comparative case study draws on the principles of realist evaluation using a qualitative approach concerned with testing and refining program theories by exploring the complex and dynamic interaction among context, mechanism, and outcome. The methods in this study included participant observations, document analysis, semi-structured individual interviews, and focus groups. We performed an interpretive analysis, which explored the context-mechanism-outcome relationship using the guiding question, “what works, for whom, under what circumstances, and why?” Results Two broad mechanisms appeared to enable skills acquisition and routinization of video consultations: informal workplace learning and adjusting the use of video consultations to professional judgment. The three units had different approaches to the implementation and training and, as such, had different outcomes. First, the skills acquired in the units differed; therefore, how and with whom they used video consultations varied. Second, video consultation use was more likely to be adjusted to workflows if unit managers were responsive to staff’s professional judgments regarding patients, as was evident in all three units. Conclusion Our study shows that a formal training course alone is insufficient to provide healthcare professionals with the skills needed to use video consultations in workplace practice. Informal workplace learning with support on the spot and continuous follow-up seems to equip healthcare professionals with the skills they need to use video consultations. Video consultations are more likely to be used confidently if novel workflows are adjusted to health care professionals' knowledge, skills, and judgment and their concerns regarding patient soundness.
Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental urticaria by regulating the functions of mast cells and T cells
Authors: Hyun Seung Yeun , Kang Minseong , Kim Eun-Young , Park Jeong Won , Hong Ki-Sung , Chung Hyung-Min , Choi Wahn Soo , Park Se-Pill , Noh Geunwoong , Kim Hyuk Soon
Published: January 2023

Background
Contact urticaria (CU) is a representative chronic inflammatory skin disease, and the symptoms progressing in stages can cause life-threatening conditions such as anaphylaxis. Mesenchymal stem cells (MSCs) are attracting attention as therapeutic agents for immune diseases. However, studies on the efficacy and mechanism of stem cell therapy for the treatment of intractable urticaria are lacking.
Methods
The regulatory role of administered embryonic-stem-cell-derived multipotent MSCs (M-MSCs) was evaluated on mice with CU. The functions of the M-MSCs on splenic T cells and mast cells were measured by flow cytometry analysis, histological analysis, RT-PCR, and other molecular biological approaches. The mechanism of action of the M-MSCs was examined using TGF-β neutralization in vitro and in vivo.
Results
The therapeutic effects of administering M-MSCs were evaluated in the developed TMA-induced urticaria model, and it was confirmed to inhibit urticarial reactions in various conditions, such as edema, itchiness, and wheal formation. In addition, M-MSC administration enabled control of the effector T cell activities in major lymphoid and peripheral tissues as well as inhibited mast-cell degranulation in the peripheral tissues. Further, the M-MSC-mediated inhibitory effects were confirmed to be dependent on TGF-β.
Conclusions
Our findings prove that M-MSCs promote alleviation of urticaria by controlling the activation of the inflammatory effector T cells and mast cells. We also confirm that the TGF-β mechanism is an important contributor to M-MSC-mediated inhibition of urticaria.
An in silico investigation and introduction of some secondary metabolites of medicinal plants with antiviral activity and effective vitamins for the treatment of MPox
Authors: Poy Donya , Tohidfar Masoud
Published: January 2023

Unfortunately, the world today is facing the dangers of bioterrorism. Bioterrorism has a long history, and contaminated and infectious materials, corpses, and animal carcasses have been used since ancient times. Therefore, we must be prepared to deal with them. After the eradication of smallpox through vaccination, vaccination was stopped worldwide, and this caused the next and enlarged generation of orthopoxviruses, including Mpox, to be of great concern. Again today, while we have very preliminary research, we are faced with a widespread outbreak of the MPox virus around the world. One of the important and available medicinal resources for the public in all countries is the native medicinal plants of each country. In addition to the independent use of medicinal plants, they can be good medicinal supplements along with the use of approved drugs. In many studies, functional compounds derived from medicinal plants called secondary metabolites have been proven to treat various chronic diseases with anti-cancer, antibacterial, antifungal, antiviral, anti-inflammatory, and allergy activities. Because smallpox and MPox have genetically similar conserved regions, this study was planned with the approach of investigating the inhibitory mechanism of drugs that are used to treat smallpox and is approved by the FDA (Tecovirimat, Brincidofovir, and Cidofovir). Additionally, to investigate the effect of plant metabolites and vitamins on the MPox virus' cell surface protein on preventing virus entry into the cell and causing infection. So far, no studies have been reported on vitamins and plant metabolites in the inhibition of the MPox virus. Some of the valuable candidate plant metabolites in this study such as gingerol in Ginger (Zingiber officinale Roscoe), Rosmarinic acid in Selfheal (Prunella vulgaris L.), Rosemary (Salvia rosmarinus), and Oregano (Origanum vulgare), Gallotannin in Aleppo oak (Quercus infectoria) and in Chinese nutgall (Rhus chinensis) can be potential inhibitors to inhibit MPox virus.
Giant energy storage ultrafast microsupercapacitors via negative capacitance superlattices
Authors: Cheema Suraj , Shanker Nirmaan , Hsu Shang-Lin , Schaadt Joseph , Ellis Nathan , Cook Matthew , Rastogi Ravi , Pilawa-Podgurski Robert , Ciston Jim , Mohamed Mohamed , Salahuddin Sayeef
Published: January 2023

Dielectric electrostatic capacitors, due to their ultrafast charge-discharge capability, are attractive for high power energy storage applications. Along with ultrafast operation, on-chip integration can enable miniaturized energy storage devices for emerging autonomous microelectronics and microsystems. Additionally, state-of-the-art electrochemical miniaturized energy storage systems – microsupercapacitors and microbatteries – currently face safety, packaging, materials, and microfabrication challenges preventing on-chip technological readiness, leaving an opportunity for electrostatic microcapacitors. Here we report record-high energy storage density (ESD) and power density (PD) across all electrostatic systems in HfO2-ZrO2 (HZO)-based thin film microcapacitors integrated directly on silicon, through a three-pronged approach. First, to increase intrinsic energy storage, atomic-layer-deposited antiferroelectric HZO films are engineered near a field-driven ferroelectric phase transition to exhibit amplified charge storage via the negative capacitance (NC) effect, which enhances volumetric-ESD beyond the best-known back-end-of-the-line (BEOL) compatible dielectrics (115 J-cm−3). Second, to increase overall stored energy, superlattice engineering of amorphous-templated HZO-Al2O3 heterostructures scales-up the high-storage antiferroelectric-NC behavior to the 100 nm regime, which overcomes the conventional thickness limitations of HZO-based (anti)ferroelectricity (10-nm regime). Third, to increase storage-per-footprint, the superlattices are conformally integrated into three-dimensional (3D) capacitors, which boosts areal-ESD (areal-PD) 9-times (170-times) the best known 3D electrostatic capacitors: 80 mJ-cm−2 (300 kW-cm−2). This simultaneous demonstration of ultrahigh ESD and PD overcomes the traditional capacity-speed trade-off across the electrostatic-electrochemical energy storage hierarchy. Furthermore, integration of ultrahigh-density and ultrafast charging thin films within a BEOL-compatible process enables monolithic integration of on-chip microsupercapacitors, which opens the door for substantial energy storage and power delivery for electronic microsystems.
Intraoral Myeloid Sarcoma as an Early Manifestation of Acute Myeloid Leukemia: Case Report and Literature Review
Authors: Grossi Letícia Dantas , França Rosimeire Plimolan , Rubira Cassia Maria Fischer , Santos Paulo Sergio Da Silva
Published: January 2023

Introduction: When acute myeloid leukemia first manifests, during treatment, or after relapsing, immature myeloid cells make up the extramedullary tumor known as oral myeloid sarcoma (AML). This article's goals are to evaluate instances that have been reported in the literature and to present the clinical characteristics of oral myeloid sarcoma.
Case presentation: This case involves a 45-year-old male patient who reported considerable pain and spontaneous bleeding in the vestibular gingiva on the left side, next to the upper premolars. The clinical findings of AML included petechiae in the area of the patient's lower limbs due to thrombocytopenia, which was confirmed in the CBC, in addition to the patient's presenting symptoms of fever, weakness, bodily aches, and diarrhea. A week before to his hospital admission, he started experiencing these symptoms. The initial lab findings showed that there were 231,410 total leukocytes/mm3, 27,000 platelets/mm3, 3.39 million mm/mm3 of red blood cells, and 222,154 circulating blasts, or 96% of total leukocytes. Myelography performed shortly after admission to the hospital showed the presence of cancerous cells, and immunohistochemistry confirmed the diagnosis of AML. Even though PAX-5, CD20, TDT, and CD3 were all negative, myeloperoxidase was positive.
Conclusion: We draw the conclusion that oral myeloid sarcoma is uncommon and that it is challenging for both doctors and dentists to diagnose and treat.
Developing of case-importing teaching module-integrated 2D pathology and 3D radiology to improve learning effect in undergraduates of stomatology
Authors: Zhang Baoping , Zhang Zhidong , Guo Dingcheng , Yan Yimin , Wang Di , Lu Lizhi , Yu Xin , Su Songhua , Zhang Kailiang , Zhang Jie , Liu Bin
Published: January 2023

Purpose The teaching concept of integrated curriculum is an important means of medical education improvement, which can arouse students' enthusiasm for learning, enhance the learning effect of basic and clinical subjects, and help students to establish interdisciplinary connection. This study aimed to combine stomatologic pathology-radiology courses with instructional media and to propose a new morphological integrated teaching mode for undergraduate stomatology education. Methods In total 84 undergraduates were divided into four teaching groups: traditional (Group T), KoPa WiFi EDU system (Group K), KoPa WiFi EDU-CBCT (Group K-C), and CBCT-KoPa WiFi EDU (Group C-K). Participants received a 2-hour lecture on periapical cysts and sat a theoretical test. Corresponding groups underwent a 4-hour experimental pathology and radiology course on periapical cysts using different teaching methods. Participants repeated the theoretical test with an experimental test. Teaching effects were assessed based on objective and subjective experimental test scores and difference in theoretical test scores. Results The results indicated no significant difference in the first theoretical outcomes among four groups (P > 0.05). The second theoretical scores, objective and subjective experimental scores of integrated teaching mode with KoPa WiFi EDU system and CBCT which scored 89.29 ± 4.55, 81.00 ± 8.15, 61.57 ± 5.52 (Group K-C) and scored 87.52 ± 3.44, 80.00 ± 9.22, 58.00 ± 4.44 (Group C-K) exhibited superior teaching effects comparing to traditional teaching mode (scored 72.57 ± 3.84, 69.38 ± 4.91, 48.67 ± 5.54) and 2D teaching mode with KoPa WiFi EDU system (scored 80.43 ± 3.41, 73.00 ± 8.01, 55.67 ± 5.66) (P < 0.05). In the integrated teaching mode, subjective scores were higher in Group K-C (pathology followed by radiology) than in Group C-K (radiology followed by pathology) (P < 0.05). Long-term teaching effect of integrated mode was better than traditional mode (P < 0.05). Conclusion The K-C group combined with 2D pathology and 3D radiology in the morphology-based integrated teaching mode was the most superior one for undergraduates’ learning effects.
Forecasting Deaths and Dalys Caused by Air Pollution for Saarc Countries Using Time Series and Neural Network Models
Authors: Amer Amna , Mushtaq Nadia
Published: January 2023

The polluted air factor is strong with the passage of time and its impact can easily be assessed by observing the related data. This research is designed to understand to what extent air pollution will contribute to deaths and DALYs in SARRC countries. Death and DALYs rates in SARRC countries due to air pollution are positively perceived. This study used time series and machine learning methods for forecasting deaths and DALYs caused by air pollution using machine learning techniques such as ARIMA, Exponential Smoothing, and Neural Network. Overall analysis shows that Ambient Particulate Matter Pollution (Ambient PM Pollution) and Ambient Ozone Pollution have an upward and Household Air Pollution (HAP) has a downward trend. The upward trend is an alarming factor for all the stakeholders. On the other, the downward trend means it is losing its intensity due to better behavior of people.
The effects of the Alexander Technique on Chronic Non-specific Neck Pain: A Systematic Review and Meta-analysis
Authors: Qin Di , Qin Ya xuan , Xue Lian , Wang Yu di , Peng Yong
Published: January 2023

Objective
To evaluate the clinical efficacy of the Alexander Technique courses compared to the conventional therapy in patients with chronic Non-specific neck pain.
Methods
According to PICO (participant, intervention, comparison, outcome) elements, the effects of Alexander Technique on chronic Non-specific neck pain were evaluated in this paper. PubMed, Web of Science, EBSCO, EMBESE, and Cochrane Library et al English databases were searched with a search time frame from databases build to December 31, 2021. Weighted mean differences (WMD), Standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated. We used a random-effects model to minimize the heterogeneity, and I2 test was used to assess heterogeneity.
Results
Three studies were included according to the predetermined eligibility criteria. Compared with the conventional therapy group, the merge of included studies showed that the Alexander Technique could significantly improve the pain for chronic neck pain patients, and the treatment effects can be maintained for 3–6 months with a very low heterogeneity (six-month follow-up pain outcome: SMD: -0.20, 95%CI: -0.38–0.01, P = 0.035, I2 = 15.7%; three-month follow-up pain outcome: -0.33, 95%CI: -0.53-0.13, P = 0.001, I2 = 0%). In addition, compared with the conventional therapy group, the Alexander Technique would not significantly increase adverse events (AE: RR = 1.690, 95% CI: 0.67–4.27, P = 0.267, I2 = 44.3%).
Conclusion
Although the number of studies and personnel involved was limited, the meta-analysis preliminarily indicated that the Alexander Technique courses is effective for chronic Non-specific neck pain, which is related to the follow-up time of the post-intervention. However, it’s necessary to interpret and apply the outcome of this research cautiously and the specific efficacy and mechanisms of Alexander Technique therapy are needed to be investigated to demonstrate further.
Systematic Review Registration:
PROSPERO, CRD420222361001.