bluuebunny/crossref_metadata_2025 huggingface dataset:
GOLPH3 predicts survival of colorectal cancer patients treated with 5-fluorouracil-based adjuvant chemotherapy
Authors: Wang Zaozao , Jiang Beihai , Chen Lei , Di Jiabo , Cui Ming , Liu Maoxing , Ma Yiyuan , Yang Hong , Xing Jiadi , Zhang Chenghai , Yao Zhendan , Zhang Nan , Dong Bin , Ji Jiafu , Su Xiangqian
Published: January 2014

Background

Golgi phosphoprotein 3 (GOLPH3) has been validated as a potent oncogene involved in the progression of many types of solid tumors, and its overexpression is associated with poor clinical outcome in many cancers. However, it is still unknown the association of GOLPH3 expression with the prognosis of colorectal cancer (CRC) patients who received 5-fluorouracil (5-FU)-based adjuvant chemotherapy.

Methods

The expression of GOLPH3 was determined by qRT-PCR and immunohistochemistry in colorectal tissues from CRC patients treated with 5-FU based adjuvant chemotherapy after surgery. The association of GOLPH3 with clinicopathologic features and prognosis was analysed. The effects of GOLPH3 on 5-FU sensitivity were examined in CRC cell lines.

Results

GOLPH3 expression was elevated in CRC tissues compared with matched adjacent noncancerous tissues. Kaplan-Meier survival curves indicated that high GOLPH3 expression was significantly associated with prolonged disease-free survival (DFS, P = 0.002) and overall survival (OS, P = 0.011) in patients who received 5-FU-based adjuvant chemotherapy. Moreover, multivariate analysis showed that GOLPH3 expression was an independent prognostic factor for DFS in CRC patients treated with 5-FU-based chemotherapy (HR, 0.468; 95%CI, 0.222-0.987; P = 0.046). In vitro, overexpression of GOLPH3 facilitated the 5-FU chemosensitivity in CRC cells; while siRNA-mediated knockdown of GOLPH3 reduced the sensitivity of CRC cells to 5-FU-induced apoptosis.

Conclusions

Our results suggest that GOLPH3 is associated with prognosis in CRC patients treated with postoperative 5-FU-based adjuvant chemotherapy, and may serve as a potential indicator to predict 5-FU chemosensitivity.
Association between Common Genetic Variants in the Opioid Pathway and Smoking Behaviors in Chinese Men
Authors: Fang Juan , Wang Xiaohong , He Bei
Published: January 2014

Background

There is biological evidence that the brain opioidergic system plays a critical role in the addictive properties of nicotine. The purpose of the present study was to examine the associations of single nucleotide polymorphisms (SNPs) in the genes encoding mu-opioid receptor (MOR) and the MOR-interacting proteins (including OPRM1, ARRB2, and HINT1) with smoking behaviors in Chinese men.

Methods

A total of 284 subjects (including current and ex-smokers) were recruited. Special questionnaires were used to assess smoking behaviors including age of smoking initiation, daily cigarette consumption, and Fagerström test for nicotine dependence (FTND) score. Participant samples were genotyped for six SNPs in the opioid pathway genes: rs1799971 in OPRM1, rs1045280, rs2036657 and rs3786047 in ARRB2, rs3852209 and rs2278060 in HINT1. Linear and logistic regression models were used to determine single-locus and haplotype-based association analyses.

Results

There was no significant association between any of SNPs analyzed and smoking behaviors. Logistic regression analyses under dominant, recessive, and additive models showed no significant associations of the six SNPs with smoking status (current vs. ex-smokers). After adjustment for age at enrollment and smoking initiation age, HINT1 rs3852209 was significantly associated with smoking status with an OR of 0.54 (95% CI, 0.31-0.95; P = 0.03) under dominant inheritance model. No haplotypes in ARRB2 or HINT1 were related to smoking status.

Conclusions

The present study indicates no significant association between common genetic variations in MOR and MOR-interacting proteins and smoking behaviors in Chinese men, and gives suggestive evidence that HINT1 rs3852209 may be related to smoking status. The findings require confirmation from further studies in additional larger samples.
Expression of serum amyloid A in uterine cervical cancer
Authors: Ren Yanjie , Wang He , Lu Donghao , Xie Xiaoyan , Chen Xinlian , Peng Jing , Hu Qian , Shi Gang , Liu Shanling
Published: January 2014

Background

As an acute-phase protein, serum amyloid A (SAA) is expressed primarily in the liver. However, its expression in extrahepatic tissues, especially in tumor tissues, was also demonstrated recently. In our study, we investigated the expression of SAA in uterine cervical carcinomas, and our results suggested its potential as a serum biomarker.

Methods

Quantitative real-time polymerase chain reaction (RT-PCR), immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) were used to evaluate the SAA gene and protein expression levels in the tissues and sera of patients with non-neoplastic lesions (NNLs), cervical intraepithelial neoplasia (CIN) and cervical carcinoma (CC).

Results

Compared with NNLs, the SAA gene (SAA1andSAA4) expression levels were significantly higher in uterine CC (mean copy numbers: 138.7 vs. 5.01, P < 0.000; and 1.8 vs. 0.079, P = 0.001, respectively) by real-time PCR. IHC revealed cytoplasmic SAA protein staining in tissues from adenocarcinoma and squamous cell carcinoma of the cervix. The median serum concentrations (μg/ml) of SAA were 6.02 in patients with NNLs and 10.98 in patients with CIN (P = 0.31). In contrast, the median serum SAA concentration was 23.7 μg/ml in uterine CC patients, which was significantly higher than the SAA concentrations of the NNL group (P = 0.002) and the CIN group (P = 0.024).

Conclusions

Our data suggested that SAA might be a uterine CC cell product. High SAA concentrations in the serum of CC patients may have a role in monitoring disease occurrence and could have therapeutic applications.

Virtual slides

The virtual slide(s) for this article can be found here:http://www.diagnosticpathology.diagnomx.eu/vs/1433263219102962
Effect of pumpkin on the quality characteristics and storage quality of aerobically packaged chicken sausages
Authors: Zargar Fayaz Ahmed , Kumar Sunil , Bhat Zuhaib Fayaz , Kumar Pavan
Published: January 2014

The present study was undertaken to evaluate the effect of different levels of pumpkin on the quality characteristics of chicken sausages. The pumpkin was incorporated at three different levels viz. 6, 12 and 18 percent replacing lean meat in the formulation. The products were analyzed for various physicochemical and sensory attributes. pH, emulsion stability, cooking yield, crude protein, ether extract and ash content of the products showed significantly (p < 0.05) decreasing trend with increasing levels of incorporation of pumpkin however, there was a significant (p < 0.05) increase in the moisture and crude fibre content. Based on various parameters, 12 percent level of incorporation was optimized as best. Chicken sausages with optimum level of pumpkin along with control were aerobically packaged in LDPE pouches and assessed for storage quality under refrigerated (4 ± 1°C) conditions. The mean values of pH and all the sensory parameters showed significantly (p < 0.05) decreasing trend for both control as well as treatment samples whereas TBARS (mg malonaldehyde/kg) value, total plate count (log cfu/g) and yeast and mould count (log cfu/g) showed significantly (p < 0.05) increasing trend with storage. Coliforms (log cfu/g) were not detected throughout the period of storage. Thus, fibre enriched chicken sausages could be successfully stored for a period of 14 days at refrigeration temperature (4 ± 1°C) without any significant loss in quality.
Theory of CBM AVO: I. Characteristics of anomaly and why it is so
Authors: Chen Xin-Ping , Huo Quanming , Lin Jiandong , Wang Yang , Sun Fenjin , Li Wuzhong , Li Guizhong
Published: January 2014

Based on the inverse correlations between methane content and elastic parameters of coalbed methane (CBM) reservoirs and on geomodulus approximation of Zoeppritz equations, we study characteristics of CBM amplitude versus offset (AVO) anomaly. Our research first suggests that CBM AVO cannot, and needs not, cling to Poisson’s Ratio as AVO for conventional gas (C-gas) does and that various approximations of Zoeppritz equations for C-gas AVO can be applied to CBM AVO though the elastic contrasts at boundaries of CBM reservoirs cannot be said to be small compared to unity. We then show that the sweet spots within a brine-saturated high- and/or medium-rank CBM reservoir can have only Class IV AVO anomaly. The reason is that all of the three elastic reflectivities, i.e., [Formula: see text] reflectivity, [Formula: see text] reflectivity, and [Formula: see text] reflectivity, at one and the same boundary of a CBM reservoir, are always of the same sign and that [Formula: see text] reflectivity or density reflectivity or both are significant in comparison with [Formula: see text] reflectivity. Finally, we propose that density reflectivity be an indicator of methane content of a CBM reservoir whereas [Formula: see text] reflectivity should be an indicator of permeability.
Two Concepts of Religious Freedom in the European Court of Human Rights
Authors: Bhuta Nehal
Published: January 2014

In this article, Bhuta revisits the jurisprudence of the European Court of Human Rights’ interpretation of religious freedom in the headscarf cases. He considers how recent historical work on the history of religious freedom and freedom of conscience opens up a new interpretation of these decisions. The court has been criticized as adopting a militantly secular approach to the presence of Islamic religious symbols in the public sphere, one seemingly inconsistent with its decision in the Lautsi case permitting the display of crucifixes in Italian classrooms. Bhuta’s essay argues that the inconsistency reflects not, or not only, a cultural hostility toward Islamic religious symbols, nor an unforgiving secularism. Rather, the cases turn on an understanding of certain religious symbols as threats to public order and harbingers of sectarian strife. This understanding evokes two different historical understandings of the concept of freedom of conscience: an early modern preoccupation with religious plurality as threatening public order, and a postwar understanding of religious freedom as the protection of secularized Christian values against the totalitarian propensities of modern politics.
From Communist to Muslim: European Human Rights, the Cold War, and Religious Liberty
Authors: Moyn Samuel
Published: January 2014

This essay contends that contemporary headscarf and related cases in the European Court of Human Rights draw not solely upon the exclusionary legacy of Western secularism but also upon the exclusionary legacy of Western hostility to secularism. One of the avatars of the contemporary Muslim, whose practices are viewed as inimical by the court to democracy’s essentials, is the communist. This argument is pursued through an examination of the history of the middle of the twentieth century, when human rights became a supranational dream and the European human rights architecture was designed.
US Evangelicals and the Politics of Slave Redemption as Religious Freedom in Sudan
Authors: McAlister Melani
Published: January 2014

In the 1990s and early 2000s, the civil war in Sudan and the fate of Christians there became the abiding international preoccupation of US evangelicals. Framing the complex issues in Sudan as straightforward matters of religious and racial oppression, the Americans became activists, determined to change US policy toward Sudan. One of the signature activities of the Sudan movement was the practice of “slave redemption,” in which activists purchased people who had been abducted by northern militias, bringing them back to their villages in southern Sudan. Overall, the conflict in Sudan was one aspect of a fundamental transformation, in which US evangelicals wove themselves into a global, self-consciously decolonizing church, built in part on a narrative of its own suffering.
A Leap of Faith: The Construction of Hindu Majoritarianism Through Secular Law
Authors: Kapur Ratna
Published: January 2014

This article describes the competing models of secularism that have been debated and contested in postcolonial India. I focus on the constitutional legal discourse and judicial pronouncements on the meaning of secularism in India and on the increasing influence of the Hindu Right—a conservative and religious political movement seeking to set up India as a Hindu state—on shaping the contours of secularism in contemporary law. The struggle over the meaning of secularism came to a head in an Indian High Court decision in 2010. The case involved a dispute over the legal title to a piece of land in the northern Indian town of Ayodhya, where a sixteenth-century mosque once stood and was destroyed by the mobs of the Hindu Right, and the Hindu Right’s claim that the site marks the spot where the Hindu god Ram was born. The case reveals how the right to freedom of religion has been used to establish and reinforce Hindu majoritarianism through secular law in India.
The Weakest Link of Managed Democracy: How the Parliament Gave Birth to Nonparliamentary Politics
Authors: Budraitskis Ilya
Published: January 2014

In his essay “The Weakest Link of Managed Democracy: How the Parliament Gave Birth to Nonparliamentary Politics,” Ilya Budraitskis reflects on the model of “managed democracy” in Russian political culture and on the specific place of the Russian Parliament. In December 2011, many cases of falsification during the Parliamentary elections triggered a grassroots protest that was unprecedented in contemporary Russian history. For many years, Putin’s model of managed democracy has ensured that the Russian Parliament was the weakest branch of the State and at the same time the most discredited in eyes of society. However, paradoxically, the desire for a return to full-fledged parliamentary politics and representative democracy proved decisive for the emergence of nonparliamentary grassroots politics. This conjuncture is very different from that which exists in Western Europe and the United States, where mass distrust targets the system of representative democracy as such, without an aspiration to “improve” its shortcomings or distortions. It also differs from the Arab Spring revolutions, which attempted to destroy the corrupted political regimes as wholes. In his essay Budraitskis briefly traces the genealogy of this particular predicament since its dark origin in the 1993 shellting of the Parliament and discusses it in connection with the strategies and tactics of current protests.
The “Two Russias” Culture War: Constructions of the “People” During the 2011-2013 Protests
Authors: Matveev Ilya
Published: January 2014

When the protests in Russia erupted in 2011-2013, they soon became encapsulated by one particular interpretation. According to the public discourse supported both by the liberal mainstream and by the Kremlin propagandists, there are two social groups in Russia, almost two distinct nations: an apathetic and conformist people and an enlightened minority (which includes the protesters). This essay proposes that the culture war waged by the liberal opposition coexists with government propaganda in a kind of symbiosis that blocks the creation of a broader popular protest movement and outlines the possibilities of unlocking this trap.
A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog
Authors: Hagelkruys Astrid , Lagger Sabine , Krahmer Julia , Leopoldi Alexandra , Artaker Matthias , Pusch Oliver , Zezula Jürgen , Weissmann Simon , Xie Yunli , Schöfer Christian , Schlederer Michaela , Brosch Gerald , Matthias Patrick , Selfridge Jim , Lassmann Hans , Knoblich Jürgen A. , Seiser Christian
Published: January 2014

The histone deacetylases HDAC1 and HDAC2 are crucial regulators of chromatin structure and gene expression, thereby controlling important developmental processes. In the mouse brain, HDAC1 and HDAC2 exhibit different developmental stage- and lineage-specific expression patterns. To examine the individual contribution of these deacetylases during brain development, we deleted different combinations of Hdac1 and Hdac2 alleles in neural cells. Ablation of Hdac1 or Hdac2 by Nestin-Cre had no obvious consequences on brain development and architecture owing to compensation by the paralog. By contrast, combined deletion of Hdac1 and Hdac2 resulted in impaired chromatin structure, DNA damage, apoptosis and embryonic lethality. To dissect the individual roles of HDAC1 and HDAC2, we expressed single alleles of either Hdac1 or Hdac2 in the absence of the respective paralog in neural cells. The DNA-damage phenotype observed in double knockout brains was prevented by expression of a single allele of either Hdac1 or Hdac2. Strikingly, Hdac1-/-Hdac2+/- brains showed normal development and no obvious phenotype, whereas Hdac1+/-Hdac2-/- mice displayed impaired brain development and perinatal lethality. Hdac1+/-Hdac2-/- neural precursor cells showed reduced proliferation and premature differentiation mediated by overexpression of protein kinase C, delta, which is a direct target of HDAC2. Importantly, chemical inhibition or knockdown of protein kinase C delta was sufficient to rescue the phenotype of neural progenitor cells in vitro. Our data indicate that HDAC1 and HDAC2 have a common function in maintaining proper chromatin structures and show that HDAC2 has a unique role by controlling the fate of neural progenitors during normal brain development.
Preparation of Nanoporous Inorganic–Organic Hybrids Containing Zirconium and Asymmetrically Linking O3P–C6H4–SiO3 Unit
Authors: Maeda Kazuyuki , Otsu Masato , Kobayashi Hiroki , Kondo Atsushi
Published: January 2014

Inorganic–organic hybrid materials composed of [O3P–C6H4–SiO3] units and zirconium hydrothermally prepared in the presence of cationic surfactant showed nanoporosity and considerably high specific surface area.
Visualizing and quantifying movement from pre-recorded videos: The spectral time-lapse (STL) algorithm
Authors: Madan Christopher R. , Spetch Marcia L
Published: January 2014

When studying animal behaviour within an open environment, movement-related data are often important for behavioural analyses. Therefore, simple and efficient techniques are needed to present and analyze the data of such movements. However, it is challenging to present both spatial and temporal information of movements within a two-dimensional image representation. To address this challenge, we developed the spectral time-lapse (STL) algorithm that re-codes an animal’s position at every time point with a time-specific color, and overlays it with a reference frame of the video, to produce a summary image. We additionally incorporated automated motion tracking, such that the animal’s position can be extracted and summary statistics such as path length and duration can be calculated, as well as instantaneous velocity and acceleration. Here we describe the STL algorithm and offer a freely available MATLAB toolbox that implements the algorithm and allows for a large degree of end-user control and flexibility.
Seed propagation of filbert
Authors: Лоай  , Loay Sahib Radi Alrmashdi
Published: January 2014

The studies found that the most promising is the autumn sowing with pre stratification within 30 days. This provides greater germination energy and output of seedlings for 1 ha and plants have maximum increase in height. In the average 3-year greatest output of standard seedlings compared with the control was in the autumn sowing after 30 days of pre-stratification of seeds and it was 377, 7 thousand units from 1 ha. Also, studies have shown that in the autumn seeds sowing output of standard seedlings is in 1.5…1.7 times higher than during the spring sowing. Obtained materials were processed statistically, which increases their reliability.
Assessing the impact of polyacrylamide on indicators of soil biological activity
Authors: Голядкина  , Golyadkina Inna
Published: January 2014

This paper examines the influence of polyacrylamide on soil biological activity. The results of the incubation experiment conducted in the laboratory are given. Carbon dioxide gas release or soil respiration is- one of the indicators of soil biological activity. Determination of the amount of released CO2 was carried out titrimetrically. Aliquots of alkali titrated continuously throughout the experiment. The graph presents the resulting effect of introducing polyacrylamide into the soil on release of total CO2. Finally the article presents conclusions and puts the problems of further study and system analysis of application of polya-crylamide in the active soil environment.
About natural regeneration of English oak growing under the canopy of maternal stand
Authors: Харченко  , Kharchenko Nikolay , Харченко  , Kharchenko Nikolay
Published: January 2014

Oak is practically not renewed naturally under the canopy of maternal tree stand under the Central forest steppe. Conversion of oak natural regeneration in knots (with its subsequent total loss) caused by the complex of reasons: From the very young age oak needs enough amount of light (70…80 %). Based on our own research and careful study of the literature on this issue, we conclude that eventually the inability of oak to renew and grow under maternal canopy, changing generations, its biological property. Thus, oak, having formed forest environment, provides the further evolution of forest ecosystems of forest steppe within it.
Adaptive structural features of mammals holes under conditions of anthropogenic landscape of Middle Reach of the Don River
Authors: Харченко  , Kharchenko Nikolay
Published: January 2014

The paper presents and proves the extended meaning of the term hole, its structural components (elements of holes), the classification of holes on complexity of their structure, functional purpose. Issues of formation and evolution of earth lifestyle under changing conditions of forest steppe are addressed. Connection of the amount of spatial structure of holes of varying complexity and function of the unit with the changed landscape, terrain, character and proximity to forage fields, peculiarities of anthropogenic factors of disturbance, etc.
Efficient and environmentally friendly technologies of stumps removal on fellings
Authors: Поздняков  , Pozdnyakov Evgeniy
Published: January 2014

Shredding of stumps below the soil surface is constrained by intense abrasion of the cutting elements as a result of their interaction with the soil particles. Therefore, to solve this problem is to remove the stump from the upper soil layer. To perform this operation as a working bodies rip-strip off elements are encouraged to use in the form of pieces of rope that will not only prepare the ground around the stump, but also clear it from adhering soil. Application of this technology will reduce the abrasion and increase grinding period of cutting elements of machines for grinding stumps, thereby increasing their productivity.
Methodical maintenance of strategic risk assessment of innovative activity of commercial bank
Authors: Ерошкин  , Eroshkin Yuriy
Published: January 2014

One of recognized competence in our country strategic management methods is balanced scorecard, by which measures aimed at achieving the strategic goals of the company are developed. In this article, based on a balanced scorecard, approach to modeling of strategic Internet banking using techniques of cognitive modeling is sugges-ted. This approach allows you to set barriers to inefficient solutions and find ways to reduce risks.
Forms of supporting the development of entrepreneurship in the forest sector of CCR
Authors: Шанянь  , Shanyan Bao , Денисова  , Denisova Yuliya , Морковина  , Morkovina Svetlana , Драпалюк  , Drapalyuk Olga
Published: January 2014

In forestry of sparsely wooded areas there are few stable and effectively working entrep-reneurs. Government business support tools can be reflected in the creation of conditions for the growth of the attractiveness of forestry, use of benefits and compensation to forest users and ensure proper communication in forestry by implementing mechanisms of outsourcing, sub-contracting and public-pri-vate partnerships.
MULTIPURPOSE HUMAN MEASURING. PART II
Authors: Леонтьев  , Leontev Boris
Published: January 2014

The most critical human mission in any country should be carried out as

a result of personality’s preliminary selection. Any target human selection

and rating are not only within the particular area of science, such as the

psychology, sociology, economics or law. Rating and assessment should

be integrated and complex. Each indicators criteria of the human resource

capacity, capital and factors should be measurable and they should be

also known to the individual. Open, massive, widespread and mandatory

human dimensions characterize the level of civilization of the relationship

in any modern state. In order to improve the economy the designee

for high and responsible positions should be more sober evaluated and

therefore, first of all, it is important to take into account what is really

done by this individual as the author and ideologist of given direction.

The author of given publication offers the comprehensive methodology

for human quality categories assessment and rating.
STATE REGULATION OF SOCIAL MOBILITY
Authors: Гендин  , Gendin G.
Published: January 2014

state in a labor market from the point of view of a problem of social mobility is considered. Vertical social mobility is an important condition of effective operation of the social elevator. The emphasis is placed on social risks which are inevitable in case operation of the social elevator is significantly broken. There are two opposite points of view on how the state has to regulate a labor market. Arguments of those who considers are analyzed that state intervention in a labor market has to be minimum, and social support has to be carried out by redistribution of the income through taxes. These arguments are compared to a position of those who considers that the help to unprotected groups, such as disabled people and youth the state has to render directly, for example, by quoting. As an example of a solution of the problem of social mobility the system of quoting of workplaces existing in Moscow for unprotected categories – youth and disabled people is analyzed.
STATE SOCIAL POLICY FOR YOUTH: ODELS, CLASSIFICATION, ACTUAL PROBLEMS
Authors: Лукьянова  , Lukyanova Tatyana , Ловчева  , Lovcheva Marina , Кибанов  , Kibanov Ardalon
Published: January 2014

Activity of the state plays the major function in development and realization

of youth policy of Russia, it is directed on creation of legal, economic

and organizational conditions and guarantees for self-realization

of the identity of the young man and development of youth associations,

movements and initiatives. The most important means of involvement

of youth in political life and the social and labor relations is formation of

system of ideas and the principles concerning a place and a role of young

generation in the society, making base for effective joint practical activities

of the state, employers, public organizations and other social institutes

on realization of these ideas and provisions for formation and development

of youth, realization of its creative potentialities in interests of society. In

article problems of distribution of responsibility between the state,

business and noncommercial sector are considered at realization of youth

policy of Russia and other countries.
Practical aspects of knowledge management in learning organization
Authors: Коробкина  , Korobkina M.
Published: January 2014

The article deals with urgent problems of knowledge management in

learning organizations; discusses the practical aspect of the company,

based on knowledge; investigates the problems and prospects of learning

organizations. The article aims to identify the mechanisms of corporate

knowledge management in the learning organization. The author

considers knowledge as a result of mental activity, there is a «people´s

minds». Considered formalized and tacit knowledge, as true learning

organization. Additionally, the article provides practical advice for learning

organizations, developing the knowledge management function. The

function of knowledge management is seen as an essential component

of organizational learning. In conclusion, disclosed the problems and

prospects of learning organizations, as well as considering the prospect

of becoming a learning organization. The article is based on an analysis

of the Russian and foreign experience.
INTELLECTUAL RESOURCES IN RUSSIA IN INCREASE OF EFFICIENCY OF PUBLIC CONTROL IN THE CONSUMER MARKET
Authors: Дроздова  , Drozdova K.
Published: January 2014

Public control is one of the main methods to protect the most wide range of consumers of our country and also an instrument of its modernization. Today there is a need to expand the coverage of public control. Only a United force of the citizens themselves and their intelligence and cohesion will be able to provide a decent level of life in our country and make it more effective any authority, forcing the authority to act in the interests of the people. In this article we consider possibilities of public control in the sphere of protection of the rights of consumers, legislation improvement in the sphere of public control, cooperation between the government and society when carrying out public control. There is also brought an example of successful collaboration when carrying out actions of public control. In this article the main problems of development of system of public control in the Russian Federation are described, the author offers solutions of these problems.
ETHICAL PROBLEMS OF MODERN BUSINESS AND PERSONNEL MANAGEMENT
Authors: Миргеева  , Mirgeeva V.
Published: January 2014

The fear expresses, that norms of morals and morals in modern cjnditions

of the Russian society as a whole? And the business world in particular,

are strongly dim. The concept “intelligence” not in a fashion and its disappearance

looks today as natural process. The question on necessity of

increase of business culture of the manager – manager rises, lack or which

absence sooner or later will be wrapped up by economic losses, and

further – crisis.

Difficult to consider an ethics role in the sphere of the economic relations

because of their nature based on utilitarian interest which absence

inevitably results in stagnation, degradation of economy and as a result

to fall of a standard of living of the population. Economy operate not

only economic laws. It is impossible to ignore a human factor that means

impossibility of an exception of freedom of a moral choice from economic

processes. Therefore, the moral principles too are economic

factor since rules of the free market are based that people adhere to

the general moral and ethical reference points in the course of labor

activity.
Development of Education in the Area of HR Management and Labor Economics in Far East Federal University
Authors: Савинкина  , Savinkina Larisa
Published: January 2014

The author describes the history of the Department of Personnel Management

and economy of labor in the Federal State Autonomous Educational

Institution of higher education «Far Eastern Feder-al University». Article describes the existing capabilities of department.
Effects of Competition in a Secretary Problem
Authors: Cownden Daniel , Steinsaltz David
Published: January 2014

In a novel multiplayer extension of the famous secretary problem, multiple players seek to employ secretaries from a common labour pool. Secretaries do not accept being put on hold, always accept job offers immediately, and leave the labour pool once rejected by a single player. All players have an identical preference for secretaries, and all players seek to optimize the probability of obtaining the best of all n secretaries. We find that in the Nash equilibrium, as the number, N, of players searching the labour pool grows, the optimal strategy converges to a simple function of N. For the two-player case we also compute how much players can gain through cooperation and how the optimal strategy changes under a payoff structure that promotes spite.
State Policies and Practices in Behavior Supports for Persons With Intellectual and Developmental Disabilities in the United States: A National Survey
Authors: Rotholz David A. , Moseley Charles R. , Carlson Kinsey B.
Published: January 2014

Providing effective behavioral supports to decrease challenging behavior and replace it with appropriate alternative skills is essential to meeting the needs of many individuals with intellectual and developmental disabilities (IDD). It is also necessary for fulfilling the requirements of Medicaid-funded individual support plans and is important for moral, ethical, and societal reasons. Unfortunately, there is no national standard for behavioral support practices or source of information on the status of behavior support policies, practices, and services for adults with IDD at either state or national levels. The collection of comprehensive data on state behavior support definitions, provider qualifications, training, and oversight requirements is a necessary starting point for the development of plans to address needed policy and practice changes. This survey is the first national assessment of state policies and practices regarding the definition and delivery of behavior support services to people with intellectual and developmental disabilities receiving publicly financed supports in the United States.
Teaching Students With Disabilities Efficacy Scale: Development and Validation
Authors: Dawson Heather , Scott LaRon
Published: January 2014

Promoting access to inclusive environments for students with disabilities is a critical issue facing schools. Feeling efficacious in teaching students with disabilities is a key aspect of enabling teachers to promote inclusion. This article reports on the development of a scale of teacher self-efficacy for teaching students with disabilities. It was examined with in-service (N = 288) and preservice (N = 143) teachers, and the results suggest it is a reliable and valid tool. The final version includes five subscales that define efficacy for teaching students with disabilities, all with strong statistical reliability and compelling conceptual meaning. They are: Instruction, Teacher Professionalism, Teacher Support, Classroom or Behavior Management, and Related Duties. Implications for future research and practice are discussed.
The Effect of “Measurable and Rigorous” State Performance Goals for Addressing “Free and Appropriate Public Education Within the Least Restrictive Environment”
Authors: Marks Susan , Kurth Jennifer , Pirtle Jody
Published: January 2014

Sections 616 and 642 of the 2004 Individuals with Disabilities Education Act (IDEA) required states to develop a State Performance Plan (SPP) to (a) evaluate their efforts in implementing the requirements of IDEA and (b) describe their plan for implementation of IDEA through determination of “measurable and rigorous” goals. In this article, we examine the performance targets proposed by states within the Southwest region of the United States to examine the impact that SPP targets have had on actual changes in practice focused on Indicator 5. Indicator 5 focuses on increasing the provision of special education services in the least restrictive environment (LRE). Our analysis found that actual changes on LRE measures were unaffected by SPP targets.
Invariant surfaces in Sol3 with constant mean curvature and their computer graphics
Authors: López Rafael
Published: January 2014

In Sol3 space there are three uniparametric groups of isometries. In this work we study constant mean curvature surfaces invariant by one of these groups. We analyze the geometric properties of these surfaces by means of their computer graphics. We construct explicit examples of minimal surfaces and we shall relate them with recent examples of spheres with constant mean curvature.
On successive radii of p-sums of convex bodies
Authors: González Bernardo , Hernández Cifre María A.
Published: January 2014

We study the behavior of the successive inner and outer radii with respect to the Firey p-sums of convex bodies, where p ≥ 1. For all p ≥ 1 we get upper and lower bounds for the radii of the p-sum of two convex bodies in terms of the radii of the sets. These results generalize the corresponding relations for the classical Minkowski addition.
Scalar and Ricci curvatures of special contact slant submanifolds in Sasakian space forms
Authors: Mihai Adela , Rădulescu Ioana N.
Published: January 2014

In this paper we prove a Chen inequality involving the scalar curvature and a Chen-Ricci inequality for special contact slant submanifolds of Sasakian space forms, as the contact versions of the inequalities obtained by the first author in [15] and by both authors in [17], respectively.
Non-factorial quartic double solids
Authors: Hong Kyusik
Published: January 2014

We study the factoriality of a double cover X4 of ℙ
3 ramified along a nodal quartic surface, and we formulate a natural conjecture which would answer this problem depending on the number r, 8 ≤ r ≤ 10, of nodes of X4. We prove this conjecture when there is a nonsingular quadric surface containing all the nodes of X4.
Characterization of isometric embeddings of Grassmann graphs
Authors: Pankov Mark
Published: January 2014

Let V be an n-dimensional left vector space over a division ring R. We write Gk(V ) for the Grassmannian formed by k-dimensional subspaces of V and denote by Γk(V ) the associated Grassmann graph. Let also V′ be an n0-dimensional left vector space over a division ring R0. Isometric embeddings of Γk(V ) in Γk′(V′) are classified in [13]. A classification of J(n; k)-subsets in Gk′(V′), i.e. the images of isometric embeddings of the Johnson graph J(n; k) in Γk′(V′), is presented in [12]. We characterize isometric embeddings of Γk(V ) in Γk′(V′) as mappings which transfer apartments of Gk(V) to J(n; k)-subsets of Gk′(V′). This is a generalization of the earlier result concerning apartment preserving mappings [11, Theorem 3.10].
Collineation groups of topological parallelisms
Authors: Betten Dieter , Riesinger Rolf
Published: January 2014

Let P be a topological parallelism of the real projective 3-space PG3ℝ. We investigate the group AutP of all collineations of PG3ℝ leaving P invariant. We prove that AutP is a Lie group whose dimension is at most 6. The main result of the article says: if the dimension equals 6, then P is a Clifford parallelism. Furthermore, we show that there are no topological parallelisms in PG3ℝ with a 5-dimensional group.
Die kaiserzeitliche Judengesetzgebung von Konstantin bis zur Veröffentlichung von Justinians Novelle 146 (553)
Authors: Lotter Friedrich
Published: January 2014

This treatise, which is less concerned with canonical as with historical questions, tries to derive the development of the relationship between the elites of society and church and Judaism from the relevant legal sources. Within this process, the changes that have evolved in the view taken by research are of particular importance. In contrast to the long-prevailing negative view of imperial and church politics, the approach which has become widely established since the 1980s examines the conflicts between the secular and clerical powers, but also those prevailing within the latter. According to this research the Christian emperors, starting with Constantine, largely continued the politics of pre-Christian emperors as far as Judaism was concerned. Despite frequent anti-Jewish encroachments on the part of clerical institutions, the Christian emperors and the official church (i. e. the bishops) followed in the Pauline and Augustine traditions and basically tolerated the Jews as the only non-Catholic religious group, even after the Edict of Thessalonica of 380 banned all pagan and non-Catholic cults. A clear restriction of the legal and, above all, societal position of Jews is, however, noticeable in the period of Justinian. The more recent research tries to overcome the rather selective and one-sided presentation of former approaches and seeks a more comprehensive and balanced interpretation by differentiating between the sources available and by allocating the sources from each period of reign to the categories »legal privileges, legal protection, approximation and preservation of laws, curtailment of laws and missionary concerns.«
Minimalphasigkeit – keine relevante Eigenschaft für die Regelungstechnik!
Authors: Zeitz Michael
Published: January 2014

Ursprünglich wurde die Minimalphasigkeit von H. W. Bode
eingeführt, um den eineindeutigen Zusammenhang zwischen Amplitude
und Phase des Frequenzgangs zu definieren. Beim Entwurf von
digitalen Filtern wird eine andere Definition der
Minimalphasigkeit verwendet und ein asymptotisch stabiles Filter
als minimalphasig bezeichnet, wenn auch das inverse Filter
asymptotisch stabil ist. Schließlich werden von C. I. Byrnes und
A. Isidori Systeme mit einer asymptotisch stabilen Nulldynamik als
minimalphasig bezeichnet. Wegen der nicht konsistenten
Definitionen wird dafür plädiert, den Minimalphasigkeits-Begriff
in der Regelungstechnik zu vermeiden und die Stabilität von
Filtern und der Nulldynamik mit den wohl definierten Kriterien von
Hurwitz oder Ljapunow zu beschreiben.
Personalentwicklung in wissenschaftlichen Bibliotheken
Authors: Kibler Simone
Published: January 2014

Die Vermittlung von Informationskompetenz spielt in wissenschaftlichen Bibliotheken eine zunehmend große Rolle. In der Universitätsbibliothek (UB) Braunschweig ist Informationskompetenz zu einem festen Bestandteil des Studienfaches Biologie geworden. Somit sind Bibliothekarinnen und Bibliothekare gefragt, einen Beitrag zu akademischer Lehre zu leisten. Doch welche Anforderungen birgt dies genau und wie werden Bibliothekarinnen und Bibliothekare auf diese anspruchsvolle Aufgabe vorbereitet? Dieser Frage wird im folgenden Artikel anhand des Beispiels der UB Braunschweig nachgegangen.
Cognitive Type and Visual Metaphorical Expression
Authors: Niño Douglas , Serventi Germán
Published: January 2014

The purpose of this paper is, first, to present a systematic cognitive type theory, which we believe can provide a better explanation of the semantic work of iconic signs than the iconic type theory proposed by Groupe μ (1992). The second objective is to present Conceptual Metaphor Theory (CMT) and to show its limitations in accounting for visual metaphoric phenomena. We suggest those constraints can be corrected with the cognitive type model. At the end, we attempt to illustrate how the cognitive type notion can explain visual metaphoric phenomena, taking into account the main aspects of CMT.
Bionanocomposites with enhanced antimicrobial activity and photodegradability based on low density polyethylene and nano TiO2/organoclay
Authors: Katbab Pouya , Alizadeh Maryam , Kaffashi Babak , Katbab Ali Asghar
Published: January 2014

Bionanocomposite materials with enhanced photodegradability and bactericidal activity, as well as improved gas barrier properties, were manufactured by incorporating silicate nanolayers into the structure of low density polyethylene (LDPE) filled with nano titanium dioxide (TiO2) via melt compounding. Effects of interfacial compatibilization upon developed microstructure were studied by incorporating maleated LDPE into the nanocomposites formulation. Field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), and rheo-mechanical spectroscopy (RMS) techniques were conducted to characterize the microstructure of the nanocomposites. Interfacially compatibilized TiO2/organoclay (OC) based nanocomposites exhibited shorter induction time for the onset of photodegradation, and an acceptable inactivation of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) microbe cells upon UV light irradiation, indicating enhanced photoactivity of the hybridized TiO2/OC nanosystem. TiO2/OC-based nanocomposites exhibited increased melt viscosity and pseudo solid like characteristics in melt linear viscoelastic behavior. Moreover, TiO2/OC-based nanocomposites presented improved barrier properties, which make such materials applicable for packaging applications.
Constrained swelling and instability of a temperature-sensitive hydrogel ring
Authors: Li Meie , Geng Jiasong , Zhou Jinxiong
Published: January 2014

We analyze the constrained swelling of a temperature-sensitive hydrogel ring, a key component of a previously developed adaptive liquid microlens. Hard constraints make the deformation and stress distribution within the gel nonuniform. The compressive stress may even cause the instability of the ring. We code a material model for poly(N-isopropylacrylamide) hydrogel and predict wrinkling instability at the inner periphery of the ring by using a commercial finite element method software. The presented model and the codes can be utilized to aid the design of soft devices based on temperature-sensitive hydrogels.
Weighted multilinear Hardy operators and commutators
Authors: Fu Zun Wei , Gong Shu Li , Lu Shan Zhen , Yuan Wen
Published: January 2014

In this paper, we introduce a type of
weighted multilinear Hardy operators
and obtain their sharp bounds on the product of Lebesgue spaces and central Morrey spaces.
In addition, we obtain sufficient and necessary conditions of the weight functions
so that the commutators of
the weighted multilinear Hardy operators (with symbols in
central BMO space) are bounded on the product of central Morrey spaces.
These results are further used to
prove sharp estimates of some inequalities due to Riemann–Liouville and Weyl.
Gender differences in early trauma and high-risk behaviors among street-entrenched youth in British Columbia
Authors: Saddichha Sahoo , Torchalla Iris , Krausz Michael Reinhardt
Published: January 2014

Objective: This work aimed to evaluate gender differences among the street-entrenched youth in British Columbia in terms of their demographics, experiences of childhood maltreatment, mental health issues, and substance use behaviors.

Materials and methods: Data were derived from the BC Health of the Homeless Study (BCHOHS), carried out in three cities in British Columbia, Canada. Measures included socio-demographic information, the Maudsley Addiction Profile (MAP), the Childhood Trauma Questionnaire (CTQ), the Mini International Neuropsychiatric Interview (MINI) Plus and the National Survey of Homeless Assistance Providers and Clients (NSHAPC)-Health Chapter.

Results: Youth constituted 16.5% (n=82) of the homeless population. Females (55%) outnumbered males and engaged in survival sex more frequently (17.8%; p=0.03). Males had greater substance abuse of alcohol (81.1%) and cannabis (89.2%). Depression (p=0.02) and psychosis (p=0.05) were more common among females, while panic disorder was more common among males (p=0.04). Rates of childhood trauma were similar across genders.

Conclusion: Our findings reflect trends among youth where illicit drug use may be similar among genders while males may report increased alcohol and cannabis use, possibly as a means to self medicate their panic-related symptoms. In any case, this population of street entrenched-youth frequently experiences several significant problems ranging from childhood abuse to high rates of substance abuse and mental illnesses.