bluuebunny/crossref_metadata_2025 huggingface dataset:
Bidding/Tendering Strategies: As Success Determinants of Construction Tenders
Authors:   Department of Quantity Surveying, Rivers State University, Port Harcourt., Dumo O. Mac-Barango
Published: October 2022

Bidding/Tendering Strategies provide the means through which contractors win jobs. This research examines tenders submitted by contractors with a view to assessing several of the factors that are critical and predominant in the success equation towards winning jobs. The Research also assesses the factors that influence contractors’ tenders as well as the challenges faced in the course of submitting tenders. Using both primary and secondary data sources, the research obtains data on several of the factors that impact on tenders. The statistical technique of central tendency was used for the analysis of the factors which impact on tenders. Research findings reveals as follows: Financial stability of contractor, availability of resources size of construction firm, work experience of construction firm, professional affiliation of contractors are significant variables that impact on tenders. The listed variables recorded values that were between 4.00 and 2.76. The research concludes that financial stability of the contractors with a mean score of 4.00 is the highest ranked factor whilst number of competitors with a mean score of 2.76 is ranked the least factor affecting contractors tender. The research recommends that contractors’ financial stability is a critical factor for consideration during the evaluation of tenders to be submitted by contractors and subsequently the award.
SYNANTHROPIC MAMMALS IN TRANSMISSION CYCLE OF TRYPANOSOMA CRUZI IN YUCATÁN, MEXICO
Authors: Alheli Cab-Romero Maria , Pereira da Costa Andrea , de Oliveira Jorge Costa Jaciara , Braz de Oliveira Manhães Ingridi , Emiliano da Silva Ryan , Ruiz-Piña Hugo Antonio , Reyes-Novelo Enrique Alberto , Escobedo-Ortegona Javier , Tonhosolo Renata , Marcili Arlei
Published: October 2022

OBJECTIVE: Trypanosoma cruzi comprises highly heterogeneus populations classified within six Discrete Typing Unit (DTU´s) named Tc-I to Tc-VI ans TcBat. Evolutionary history of T. cruzi has a very strong association with their mammal hosts and some phylogenetic and ecolobiologically studies suggest that ecotopes, hosts and vectors are factors that determine the different lineages of T. cruzi. METHODS: Herein we characterized T. cruzi isolates from synanthropic individuals of Didelphis virginiana and Rattus rattus captured in the village of Molas, Yucatan. RESULTS: Forty households were selected and traps were placed in the yard during January to May of 2014. Sixty six opossum (Didelphis virginiana) and twenty five rats (Rattus rattus) were captured and 13 were diagnosed as T. cruzi infected by microhematocrit and blood culture. Ten isolates of T. cruzi were obtained for phylogenetic analysis with SSU rDNA, gGAPDH and Cytochrome B genes to describe the relationships between them and classify them into the different DTU´s. CONCLUSION: This study demonstrated the participation of synanthropic animals D. virginiana and R. rattus as a reservoirs of T. cruzi in Yucatan_Mexico and the different isolates of the parasite belonged to Tc-I. The proximity of these species to the domestic environment favor the contact of the trypanosome with the human population in domestic environment.
ANOSMIA AND AGEUSIA IN COVID-19 PATIENTS: THE CYTOKINES PROFILE IN UPPER AIRWAYS
Authors: Lacerda Bachi Andre Luis , de Melo Batista dos Santos Juliana , Rodrigues Monteiro Fernanda , Rossi Marcelo , Bussador do Amaral Jônatas , Pereira Soares Camila , Araújo Valério Camila , Nascimento Chalup Vanessa , Fernandes Leite Gabriela , Almeida Flavia Jaqueline , Aurélio Palazzi Sáfadi Marco , Nobre Monteiro Paiatto Beatriz , Mott Barrientos Anna Carlota , Graça Fevereiro Aline , De Paulis Milena , Ferri Passadore Lilian , Ramalho Theresa , de Paula Vieira Rodolfo , Durigon Edison Luiz , Leal Oliveira Danielle Bruna , de Oliveira Penido Norma
Published: October 2022

OBJECTIVE: COVID-19 is a systemic disease affecting multiple organs, beyond the respiratory system. Although sensorineural symptoms, including anosmia and ageusia, have been frequently associated with milder forms of SARS-CoV-2 infection, the pathogenic mechanism and its relation with oromucosal immunomodulation remains poorly understood. Therefore, the main objective of this pilot study was to provide some pieces of evidence concerning the cytokines pattern in the mucosa of the upper airways in COVID-19 patients with and without anosmia and/or ageusia. METHODS: Samples of nasopharyngeal/oropharyngeal swabs were obtained from 12 patients diagnosed with COVID-19. The patients were separated into two groups: with anosmia and/or ageusia (A/A,n=4), and a control group with patients without anosmia and/or ageusia (NA/A,n=8). RESULTS: Mucosal cytokines concentration was determined by ELISA. Levels of IFN-γ, IL-6, and IL-10 in the mucosa of the upper airways were similar between the groups. In addition, no significant differences were found in the ratio of IFN-γ/IL-6, IFN-γ/IL-10, and IL-10/IL-6 between the two groups. However, using Pearson's correlation coefficient we found a significant positive correlations between IL-6 and IFN-γ, IL-10 and IFN-γ, and also IL-10 and IL-6 in the control group (NA/A), whereas a significant negative correlation between IL-10 and IFN-γ was found in A/A group. CONCLUSION: Our results suggest that patients with mild forms of COVID-19, presenting anosmia and/or ageusia, have an altered mucosal immune response in the upper airways. DESCRIPTORS: SARS-CoV-2, Sensorineural symptoms, IL-6, IL-10, IFN-gamma.
Mapping compares current biomass of agricultural areas in Brazil
Authors: Buriti Catarina de Oliveira , Barbosa Humberto Alves
Published: October 2022

The Satellite Image Analysis and Processing Laboratory ( Lapis ) has launched a new monitoring product, based on satellite data . It is the map of the difference in drought severity areas, in plantation areas, in Brazilian regions. The product is generated from the Normalized Difference Vegetation Index (NDVI). The map was processed in QGIS software , with data from the Meteosat-11 satellite , which has a spatial resolution of 3 km.
A LEGAL REVIEW OF STEREOTYPES, BIASES, AND DISCRIMINATION AGAINST MUSLIM-AMERICAN EMPLOYEES
Authors: Bahaudin G. Mujtaba  , Frank J. Cavico
Published: October 2022

Approximately fifteen million Muslims live and work in the United States of America. Most of these Muslims are American by birth; yet some confront discrimination, harassment, and retaliation in the workplace because of their religion. Religious discrimination is illegal in the workplace in the United States pursuant to civil rights laws. This article examines the most common challenges that American Muslims face in the workplace. The article then offers pertinent recommendations to organizational leaders so they not only can fulfill their legal duties, but also attract and retain the most qualified workers regardless of their religious affiliations, beliefs, observances, and practices.
Comparative Evaluation of Customers’ Satisfaction and Loyalty in Conventional and Islamic Banks of Pakistan
Authors: Muhammad Ilyas  , Kamran Ali
Published: October 2022

The intention of this paper is to examine the level of customer’s satisfaction inboth conventional and Islamic banks and to find out that the customers of which type of bank are more satisfied. A modified SERVQUAL model has been used for this purpose. Field survey was carried out through questionnaire based on modified SERVQUAL model. Data were collected from 500 walk-in customers of Islamic and conventional banks andanalysed through SPSS 16. The results show that the customers of Islamic banks are more satisfied and loyal than the customers of conventional banks.This study will help policy makers of Islamic and conventional banks understand the behavioural differences of customers and will also help them to align their service quality according to customer’s perceptions.
ARE THE TEACHERS ON TRACK?AN EVALUATION OF SECONDARY SCHOOL TEACHERS’ SUBJECT KNOWLEDGE COMPETENCY
Authors: Dr. Muhammad Shakir  , Dr. Irshad Hussain  , Jam Muhammad Zaffarc
Published: October 2022

The study was aimed to evaluate secondary school teachers’ subject knowledge competency. The main focus of this study was to develop teacher evaluation mechanism for secondary schools’ teachers. Objectives of the study were (a) to review the importance of standard (rubrics) to appraise the teachers’ performance level in Pakistan; (b) to assess the secondary school teachers’ subject knowledge competency based on national professional standard in Pakistan and (c) to propose recommendations for further improvement of the existing standards of teachers’ performance. The population of the study consisted on all the secondary school teachers of government sector including boys and girls situated at urban and rural areas of the province of Punjab. To conduct the observational survey of this research, a sample of 453 participants (teachers) from six districts of Punjab was selected to observe the teachers in field directly. An observational checklist was developed on the basis of prescribed levels of teacher accreditation by Policy and Planning wing of Ministry of Education, Pakistan. The collected data wereanalysed with the help of software SPSS version 16 by using statistical formulas of Chi-Square, simple mean and percentage. The analysis indicates that majority of the teachers are generally unaware of national curriculum framework. This analysis concluded that no teacher was found at the competent level (level 4) of understanding regarding national curriculum framework. Majority of them were not aware of any such document. A small number of teachers heard about curriculum frame work but did not go through document.
Criminal Background Checks in the American Employment Process
Authors: Frank J. Cavico  , Bahaudin G. Mujtaba  , Stephen C. Muffler
Published: October 2022

This article examines the important and controversial topic of criminal background checks in employment. The topic of criminal background checks in employment is indeed an important as well as controversial and difficult one in the world of business today, as this hiring practice addresses core values in society. Yet these values can conflict. One societal value is the belief that if a criminal ex-offender has paid his or her “debt to society’; then opportunities, such as employment, should be made available to such a person, just like everyone else. Business owners and managers today, however, are concerned about having an efficient, effective, and ethical workforce. Thus, they are confronted with this dilemma of conflicting values and duties as well as the responsibility of doing the “right thing” in utilising criminal background checks in the hiring process. This article will first provide certain background information pertinent to the subject of criminal background checks in employment, particularly criminal conviction and incarceration rates for minorities, as well as discuss the prevalence of background checks in employment from an American perspective. The authors also examine the legal and practical implications of background checks; and finally draw conclusions for management from the aforementioned analysis.
Bank-Specific and Social Factors of Non-Performing Loans of Pakistani Banking Sector: A Qualitative Study
Authors: Hisham Ul Hassan  , Sumaira Rehman  , Ch. Abdul Khaliq
Published: October 2022

Purpose: This study aims at building up a model clarifying the relationship mong bank-specific, social factors and non-performing loans on one hand and on the other hand, exploring this model in the setting of Pakistani Banking sector as limited interest has been given in existing literature in defining the relationship among bank specific, social factors and non-performing loans.

Design/ Methodology/ Approach: Based on the interpretive phenomenological approach, the study explores various influencing factors of Non-Performing Loans in unique setting of PakistaniBanking sector. The methodology helpsanalyse data about bank specific and social factors of Non-Performing Loans as well as to have an insight in examining the nature of their relationship with each other.

Findings: The results show that various bank-specific factors like lenient credit terms, monitoring, bank ownership, bank size, diversification of loans and credit assessment have significant effect on Non-Performing Loans, whereas interest has a weak significance on NPLs. Thus, banks should carefully look after these factors in order to control NPLs. The social factor like corruption has an insignificant effect on NPLs and political pressure has been an important factor in explaining the Non Performing Loans, especially in case of state owned banks. The government needs to lessen down the level of interference in the financial decisions of the state owned banks so that these banks can independently make their credit decisions without any political pressure.

Originality/value: This ground-breaking work on Non-Performing Loans and its factors may help the entire Pakistani banking sector to control NonPerforming Loans.
Historical and Modern Management Practices Applied at Disney World: Out with the Old and in with the New?
Authors: Sarah Patterson  , Bahaudin G. Mujtaba
Published: October 2022

In today’s expanding and ever-evolving global marketplace, managers are beginning to be required to work with their companies and employees in entirely different ways. Explained in-depth throughout the entirety of the article is the 20th century management techniques pioneered by Taylor, then reformed by Weber and Fayol, contrasted against the ahead-of-its-time behavioural management and the 21st century market-based management styles. Credit will, of course, be given where earned to the first style since it is focused on a centralised and bureaucratic method that worked extremely well in the Industrial Revolution time period. Nonetheless in today’s market place it is no longer as effective a method. At present, managers must learn more from what the second style emphasises, which is a more horizontal and incorporated standpoint. Conveniently,enough the company incorporated into this article is the perfect example to use when illustrating both sets of management techniques. Disney’s longest-standing CEO Michael Eisner followed the conservative administrative approach, while his successor, Robert Iger follows the behavioural method. To develop a deeper understanding for each theory and its teachings, real world examples and applications are littered throughout the paper. Implications and recommendations for managers who want to create immediate and measureable value for their firms are provided.
External Debt Sustainability Analysis: A Case of SAARC Countries
Authors: Muhammad Ramzan Sheikh  , Muhammad Nauman Abbasi  , Saliha Iqbal  , Salman Masood
Published: October 2022

This study conducts the external debt sustainability analysis for the eight SAARC economies using the data from 2000 to 2013. Three types of techniques- univariate unit root tests, panel unit root tests and the cointegration tests are applied. According to the first and second type of tests results, the external debt of SAARC economies is unsustainable individually but sustainable as a whole. The results of third type of tests reveal that the external debt of the SAARC economies is unsustainable individually and wholly with some exceptions. The study deduces that the external debt of SAARC countries is unsustainable so they should exploit their domestic resources instead of going for the foreign resources and encourage saving and investment environment in their countries.
Impact of Knowledge based HR Practices on Innovation with the Mediating Effect on Employee’s Creativity
Authors: Kashif Mahmood  , Chaudhary Abdul Rehman  , Dr. Muqqadas Rehman  , Faiza Ali
Published: October 2022

The purpose of this research is to concentrate on the mindful and orderly administrative activities for business with knowledge in firms (i.e. knowledge management (KM) practices), which aims at innovation performance improvements through proactive management of knowledge assets. The study examined the impact that the KM practices have on innovation performance. A study was conducted to obtain experiential evidence by using questionnaire. The data have been collected from 366 respondents from FMCGs within Lahore City. A structured questionnaire was framed containing 27 questions. This research is significant for practitioners, policy makers and from theoretical point of view. Quantitative data have been collected for research purpose. The results reveal that employee’s creativity plays a positive role in innovation of an organization. Therefore, all hypotheses are acknowledged. The study clarifies that the knowledge based HR practices have effect on innovation and it affects positively employee’s creativity too.
The Mediating Impact of Self-Confidence on Relationship of Perceived Formal Support and Entrepreneurial Intention in the Education Sector of Pakistan
Authors: Dr. Kashif Rathore  , Saba Shaukat  , Kashif Ali  , Arshad Haroon
Published: October 2022

The purpose of this study is to find out the mediating influence of selfconfidence level (SC) on the relationship of perceived formal support (PFS) and students‟ entrepreneurial intention (EI). There are few studies that investigated the influence of mediator (self confidence level). As a result, this study contributes to the area of entrepreneurship. The study used a crosssectional research design. The population of this study consists of final year undergraduates of University of the Punjab, Lahore. Sample consists of 250 students from three departments. Zero-order correlation, multiple regression analysis and t-test are used for data analysis. The multiple regression analysis shows that self-confidence level (SC) significantly mediates the relationship of perceived formal support (PFS) and entrepreneurial intentions (EI) of students. Furthermore, t-test shows that male and female students significantly different in terms of perceived formal support (PFS) but there is no difference between male and female students in terms of their entrepreneurial intentions (EI).
Editorial of International Journal of Pharmacy and Integrated Health Sciences
Authors: Munir Abubakar
Published: October 2022

It gives me pleasure to announce the very first edition of the ‘International Journal of pharmacy and integrated health sciences', a bi-annual journal published by the Pharmacy Department of Superior University.

Only a year ago, the honorable Rector Dr. Sumaira Rehman and Chairman of the group, Prof Dr. Chaudhry Abdul Rehman along with Directors of the Research Committee ordained a team of enthusiastic researchers to venture on publishing a new journal in the field of medicine and allied sciences.

Such an edition was dire felt need of presenting the academic quality of Pharmacy Department and Research carried under the supervision of ORIC, steering it to next level; meeting both the need of market and accepted health standards of the current time. The Journal has been carefully designed to pertain to the most substantial and valid information from the field of medicine delivered at a level capable of sustaining global standards of research, quality, and communication.

The journal is designed to be published, both in hard copy and in an electronic format with the online release of abstracts and another database. Through this platform, I invite all researchers from dedicated fields of science and medicine to join hands for presenting their work under a platform that shall reach out to many.
PREVALENCE OF OSTEOPOROSIS AND ITS IMPACT ON QUALITY OF LIFE OF PRE AND POST MENOPAUSAL WOMEN
Authors: Ishtiyaq Wajeeha , Tariq Arslan , Fatima Azka
Published: October 2022

Background: Globally, osteoporosis is one of the major health concerns as there is a drastic increase in incident of osteoporotic related fractures. It is a silent bone disease which is characterized by a progressive decrease in bone mass and density(2). In Pakistan, occurrence of osteoporosis is quite common among females and negatively affects patient’s quality of life.(6)

Aims and Objectives: The aim of current study is to associate the osteoporosis prevalence in both pre and post menopause, and also to evaluate quality of life and its awareness.

Methodology: A survey based study was conducted and data was collected from patients by using a questionnaireand analyzed by the application of statistics.

Results: The results of current study have revealed that incidence of osteoporosis is greater in post menopausal women as compared to pre menopausal women. High occurrence of disease in post menopausal is due to a direct relationship between levels of estrogen and osteoporosis. In post menopausal women decrease level of estrogen enhances bone reabsorption which causes increase bone fragility. Hence, all the post menopausal women should be evaluated for osteoporosis.

Conclusion: Lack of understanding about disease, imbalance diet, poor treatment and diagnosis increase the risk for developing osteoporosis. Furthermore severe pain, deprive of sleep and inability to do work also adds to the demotion in patient’s quality of life. So in order to reduce incidence rate and for the betterment in quality of patient’s life having osteoporosis, it is necessary to promote awareness, modification in life style, patient counseling, accessibility to treatment and prior diagnosis of disease
IMPACT OF PHARMACEUTICAL BIOTECHNOLOGY
Authors: Aslam Aysha , Ishtiyaq Wajeeha
Published: October 2022

We are living in an era of transformation and miracles happen each day. Biotechnology is the combination of two words “technology and biology”. The domain of Biotechnology is very wide in which cells or cellular parts, biological pathways and organisms are used to develop new innovative technologies. Novel procedures, tools and products are developing day by day, which are used in research, agriculture, industry and the health care system. Pharmaceutical Biotechnology is the application of biotechnology principles and procedures in the development of drugs. Pharmaceutical biotechnology is the quite innovative, dynamic and rapidly emerging field and driving a global alteration from illness to wellness. Since last few years, pharmaceutical biotechnology has played a key role in drug research and development, and innovatory changes have been happening in health care setups, especially in field of oncology, infectious diseases and metabolic disorders. Due to the Pharmaceutical Biotechnology, a groundbreaking transformation is occurred in the field of drug discovery. Various biotechnology techniques (i.e. cell culture, genetic modeling and immunochemistry) use in drug discovery and have also paved the way to explore new avenues of drug discovery that are beneficial to the mankind.
PHYTOCHEMICAL, FLUORESCENCE AND ANTIMICROBIAL EVALUATION OF POLY HERBAL EXTRACT
Authors: Manzoor Rizwana
Published: October 2022

Background and Objectives: Natural products and traditional medicines are of great importance. Such forms of medicine as traditional Chinese medicine, Ayurveda, Kampo, traditional Korean medicine, and Unani havebeen practiced in some areas of the world and have blossomed into orderly-regulated systems of medicine. Allium sativum L., crude drug (Liliaceae) used as herbal medicine to treat hyperglycemia, cancer, cardiovascular disease, hypertension, stress and infections. Malus domestica B., fruit (Rosaceae) possess antioxidant, antiproliferative, antimicrobial and anti-inflammatory activity and used for the treatment and prevention of asthma, diabetes and hyperlipidemia. Capsicum annum L., crude drug (Solanaceae) is used as anti-diabetic, anti cancer, anti-inflammatory, analgesic, hypolipidemic, hepatoprotective and antimicrobial agent. Foeniculum vulgare M., crude drug (Apiaceae) is used as antioxidant, antimicrobial, bronchodilatory, estrogenic, diuretic, hepatoprotective, gastroprotective and hypotensive agent. Curcuma longa L., crude drug (Zingiberaceae) is used various biological actions including anti-inflammatory, antioxidant, analgesic, antifertility, antidiabetic, anticoagulant, antiulcer and antimicrobial.

Methodology: In the current study these five medicinal plants were purchased, authenticated and extracted by method of maceration. In this research work phytochemical screening, fluorescence analysis, antimicrobial (disc diffusion method) for both antibacterial (gram positive bacteria such as Bacillus subtilis, Staphylococcus aureus, and Micrococcus lutes and gram-negative bacteria such as Serratia marcescens and Escherichia coli) and antifungal (Candida albican, and Aspergillus flavus), activity was performed in comparison with ciprofloxacin (standard disc for bacteria) and nystatin (standard disc for fungus).

Results: Phytochemical evaluation indicates the presence of alkaloids, glycosides, flavonoids, tannins, steroids, phenol, resin and saponins. The poly herbal extract is moderately effective against gram positive bacteria (Staphylococcus aureus and Micrococcus lutes), active against gram negative bacteria (Serratia marcescens and Escherichia coli) and is less susceptible against Bacillus subtilis. It is active against Aspergillus flavus and Candida albican.

Conclusion: The medicinal plants are effective to provide defense against microorganisms.
T CELL AGING IN RHEUMATOID ARTHRITIS
Authors: Maria Oubaid  , Bushra tahreem  , Toba Samreen  , Javeria Parveen  , Idress Khan
Published: October 2022

With the progression of aging, the immune system and the tendency for abnormal immunological changes are common. Individuals over the age of 50 years are susceptible to infectious diseases as well as inflammation and immune-mediated tissue damage. Aging is the main cause of disease pathology and death, continuously enhancing the risk of cardiovascular disease, malignancy, and infectious diseases. One of the important causes is higher susceptibility to autoimmune diseases like rheumatoid arthritis and other immunodeficiency syndromes. Inflammation is common in age-related pathologies. In immune cells, T lymphocytes have an extensive life cycle and show a robust copying force, constructing them sensitive to ageing-associated pathologies. In dysfunctional ageing of T-cells, protection of T-cell function and cells capable of promoting inflammation are abundant. Rheumatoid arthritis is a long-lasting autoimmune disease that mainly affects the joints. Though RA develops at an early age, the frequency of developing RA increases with the increase in age. It is also seen that RA may develop as a result of premature ageing (immunosenescence) of the immune system. In RA, T-cell ageing occurs prematurely, but the mechanism involved and their role in tissue damage is still uncertain. T-cell ageing and its effects on rheumatoid arthritis are discussed here, as well as how T-cells participate in tissue damage, acute and chronic inflammation, and the ageing process. Also review the DNA damage in response to T-cell aging, telomeric ends shortening during RA and immunosenescence, and Tcells in RA.
Le patient, le médecin et la confiance : traduction, adaptation culturelle et validation de l'échelle de confiance de Wake Forest
Authors: STAVILA AMARANDEI R , MAHUT S , SIXOU P , JAMI A
Published: October 2022

Introduction. La confiance est essentielle à la relation médecin-malade. Compte tenu de son impact sur la prise en charge des patients, et en l’absence d’outil validé en français pour pouvoir l’évaluer, il était justifié de traduire, d’adapter à la culture française et de valider une échelle anglo-saxonne existante. L’échelle de Wake Forest a été choisie car c’est une échelle de référence. Objectifs. Traduire et valider en français l’échelle de Wake Forest. Méthode. Pour la traduction et l’adaptation culturelle, les étapes ont été incluses : la préparation, la traduction de l’échelle en français, l’harmonisation des trois traductions par quatre traducteurs (première commission), la rétrotraduction, l’analyse de la rétrotraduction et l’harmonisation (deuxième commission), l’application du prétest, l’élaboration de la version définitive du test (troisième commission). La validation a été réalisée sur 100 patients consultant en cabinet de médecine générale : la qualité des items et l’a de Cronbach ont été analysés. Dans un second temps, l’analyse de la fidélité temporelle a été effectuée par la réalisation d’un test-retest. Résultats. Les difficultés rencontrées pour l’analyse et la traduction des différents items étaient hétérogènes et ont été résolues au cours des commissions. À la fin du processus et après relecture, la version finale de l’échelle de Wake Forest a été proposée. L’analyse de la qualité des items a été satisfaisante. Le coefficient a de Cronbach était à 0,89. Le test-retest était stable dans le temps. Conclusion. La traduction a été menée à bien. Aucun outil de mesure de la confiance n’avait encore été construit en France. La qualité de l’échelle produite était comparable aux traductions réalisées en Chine et aux Pays-Bas ainsi qu’à des travaux de traduction réalisés dans d’autres domaines. La procédure de traduction qui a été utilisée a été rigoureuse et a suivi de manière exhaustive les recommandations disponibles. Les traducteurs, même s’ils étaient bilingues, n’étaient pas des professionnels de la traduction. Ce travail permet de disposer, en France, d’un instrument pour évaluer la confiance des patients en leur médecin.
COMPETENCES ATTENDUES POUR L ACCUEIL D UN ADOLESCENT EN MEDECINE GENERALE. VALIDATION D UN REFERENTIEL FRANCOPHONE
Authors: LEPINE C , JEDAT V , DI PATRIZIO P , HALLER D-M , BINDER P
Published: October 2022

Introduction. Les médecins généralistes sont souvent mal à l’aise pour accueillir les adolescents en consultation, particulièrement ceux en difficulté psychologique. En 2020, il n’existait pas de référentiel de formation et d’évaluation spécifique concernant la consultation avec l’adolescent. Objectifs. Établir un référentiel des compétences attendues d’un médecin généraliste, pour l’accueil des adolescents en soins primaires. Méthode. Après synthèse de la littérature, une proposition de référentiel a été rédigée, présentant dix compétences, caractérisées chacune par trois capacités dont le contenu était détaillé. Cette proposition a été soumise à un panel de vingt et un experts francophones, selon la méthode Delphi. Il leur était demandé de juger chacune des trente capacités selon trois critères, sur une échelle de 1 à 9 : la compréhension, la pertinence, et l’applicabilité. Trois tours ont été réalisés, entre février et mai 2020. L’analyse des résultats a été effectuée selon les critères de la fondation RAND : la validité contextuelle était établie lorsque le score médian de l’accord était supérieur ou égal à 7, en l’absence de désaccord. Résultats. Le consensus, tel que défini, a été atteint au bout de deux tours pour les trente capacités, avec la participation explicite de tous les experts sur les deux tours. Des ajustements ont été validés lors d’un troisième tour. Les divergences relatives des experts portaient sur l’applicabilité des compétences, et non sur leur pertinence. Les trois rondes Delphi et le consensus obtenu ont permis de construire le premier référentiel francophone pour l’accueil de l’adolescent en médecine générale, présenté dans cet article. Conclusion. Ce premier référentiel francophone des « Compétences attendues pour l’accueil d’un adolescent en médecine générale » servira à enrichir les formations professionnelles et la certification des internes. L’étape suivante sera celle de sa transposition pédagogique.
ASSOCIATION ENTRE SYMPTOMES DEPRESSIFS ET SURVENUE ULTERIEURE DE BLESSURES ACCIDENTELLES CHEZ LES JEUNES ADOLESCENTS. UNE ETUDE POPULATIONNELLE
Authors: BERKHOUT C
Published: October 2022

En étant la cause de la moitié des décès chez l’adolescent, les blessures accidentelles sont fréquentes et entraînent de lourdes conséquences sur la santé et la réussite scolaire des adolescents, et des coûts économiques élevés. Les symptômes dépressifs (SD) sont également fréquents chez les enfants et les jeunes adolescents (10- 16 ans). Ils sont souvent chroniques, non repérés par les parents et les médecins, et souvent persistants malgré un traitement médical...
APPORTS DE LA THEORIE DE L ATTACHEMENT DANS L ANALYSE DE LA RELATION DE SOIN EN MEDECINE GENERALE. EXEMPLE DE PATIENTS TOXICOMANES
Authors: BAZIN-BOQUEIN E , VINAY A , GARNIER F , DE CASABIANCA C , BELLANGER W
Published: October 2022

Introduction. La relation de soins pose des questions épistémologiques à ceux qui s’y engagent. Sa construction est difficile avec les patients toxicomanes. En médecine générale (MG), comment rendre compte des processus psychodynamiques en jeu et de leur portée thérapeutique éventuelle ? Objectifs. Explorer les relations de soins de patients toxicomanes au regard des principes de la théorie de l’attachement. Méthode. Étude qualitative par entretiens semi-dirigés avec des patients toxicomanes de plus de 30 ans suivis en MG réalisée entre 2018 et 2019 en Anjou (France). Edicode a permis de déterminer le mode d’attachement des patients. Cet outil validé identifie, à partir du discours d’une personne, son mode d’attachement sécure ou insécure (détaché ou préoccupé). Une analyse inductive a permis d’étudier la qualité de la relation de soins. Résultats. Sept patients suivis par 7 médecins ont été interviewés. Edicode a identifié les trois modes d’attachement adulte : sécurisé, détaché et préoccupé. La qualité de la relation de soins a été analysée dans les trois groupes. Pour le groupe sécure, la distance affective avec le médecin permettait de pouvoir compter sur lui sans en dépendre. Pour le groupe détaché, la relation paraissait distante, émotionnellement désinvestie. Pour le groupe préoccupé, une relation peu distanciée témoignait d’une dépendance affective. Conclusion. Un attachement insécure exposait à la pérennisation de conduites addictives. La sécurité ou l’insécurité n’étaient pas des caractéristiques d’un individu ou d’un groupe mais un déterminant de la relation que peut engager une personne avec une autre. Tolérer la demande de sécurisation des patients toxicomanes favorisait une dynamique compréhensive et autorisait de nouvelles expériences intersubjectives. La théorie de l’attachement proposait un cadre d’analyse conceptuelle pertinent pour explorer les effets de la relation de soins en MG et pourrait constituer une nouvelle base de réflexion pour comprendre la clinique du lien intersubjectif au-delà des problématiques addictives.
MISE EN OEUVRE D UNE SUPERVISION PAR OBSERVATION DIRECTE AVEC ENREGISTREMENT VIDEO EN SITUATION AUTHENTIQUE DE SOINS
Authors: TOUATI Y , PHAN T-T , BROSSIER S , ADELINE-DUFLOT F , NEAGOE M , FERRAT E
Published: October 2022

Introduction. La supervision par observation directe avec enregistrement vidéo (SODEV) est peu utilisée en France. Objectif. L’objectif était d’expérimenter et d’évaluer la faisabilité et l’intérêt de l’utilisation de cette méthode pédagogique comme outil de formation et d’évaluation des apprentissages des étudiants de 3e cycle (E3C) de médecine générale au cours des stages ambulatoires. Méthode. Entre novembre 2017 et octobre 2018, les E3C de médecine générale de l’Université Paris-Est Créteil, en stage ambulatoire, ont recueilli des données quantitatives relatives aux enregistrements vidéo des consultations. Des données de satisfaction des E3C ont été recueillies par questionnaire en fin de stage. Des analyses descriptives et univariées de régression logistique ont été effectuées. Résultats. Sur 67 E3C éligibles, 43 (64,2 %) ont participé à l’étude en réalisant 607 enregistrements vidéo et 243 rétroactions avec leur maître de stage. Peu de patients (10,9 %) ont refusé d’être filmés. La plupart des E3C (72,1 %) considéraient la SODEV comme étant un outil d’apprentissage pertinent permettant de visualiser leurs difficultés et leurs progrès. La compétence « Relation, communication, approche centrée sur le patient » était la compétence la plus travaillée, en particulier la posture non verbale. Le temps était le principal facteur limitant la SODEV. Conclusion. La SODEV semble faisable mais nécessite d’être adaptée aux lieux de stage en termes de temps et de logistique. Elle semble utile au développement des habiletés communicationnelles des E3C de médecine générale. Elle pourrait renforcer le poids de la supervision directe dans la formation pédagogique et constituer un outil supplémentaire pour la certification des E3C.
ORGANISER UN CIRCUIT ECOS
Authors: MOLL-LLOBELL K , LOPEZ A , AMOUYAL M , CLARY B , CARBONNEL F
Published: October 2022

L’évaluation des étudiants en médecine est en pleine évolution, avec la réforme du 2e cycle (R2C) qui intègre désormais l’approche par compétences. L’examen clinique objectif et structuré (ECOS) est une méthode plus objective pour évaluer les performances des étudiants que les moyens traditionnels (question à choix multiple [QCM], question à réponse ouverte courte [QROC]…). Les ECOS seront proposés dans le cadre de la R2C sous deux formes : des ECOS certificatifs dans le cadre du certificat de compétences cliniques organisé en circuit ECOS et des ECOS formatifs, outils d’évaluation formative en stage et de préparation aux ECOS certificatifs (ECOS « blancs »). À travers la mise en place de circuits ECOS, l’étudiant est évalué sur la base de ses performances dans une série de mises en situation. Chaque station comprend un examinateur formé à cet effet, et parfois un patient standardisé. L’organisation d’un circuit ECOS est un processus complexe et rigoureux nécessitant la mise en place d’équipes administratives et enseignantes dédiées. Une organisation en amont est nécessaire pour en assurer la qualité. À l’approche des examens dématérialisés nationaux qui vont intégrer ce nouveau mode d’évaluation, nous proposons un guide pour accompagner les enseignants de médecine générale dans leur mise en oeuvre.
EVITER LA VISCO-SUPPLEMENTATION DANS LA GONARTHROSE
Authors: SCIENTIFIQUE C
Published: October 2022

La gonarthrose est une pathologie fréquente en population générale : 15 % des personnes de plus de 45 ans ont des symptômes (incapacité physique ou douleur) qui lui sont liés1. L’injection intra-articulaire d’acide hyaluronique est un traitement souvent proposé. Cependant, il n’est plus remboursé par l’Assurance maladie depuis 2017, car son efficacité et sa sécurité d’emploi sont controversées. Une méta-analyse ayant inclus 169 essais randomisés a évalué l’efficacité (soulagement de la douleur et amélioration de la fonction articulaire) et les risques de la visco-supplémentation d’acide hyaluronique comparativement à des injections intra-articulaires de placebo ou des soins usuels2. La visco-supplémentation a entraîné une diminution de l’intensité de la douleur de l’ordre de -2 mm en moyenne sur une échelle visuelle analogique de 100 mm (IC95 % = -3,8 ; -0,5 mm) ; et une faible amélioration de la fonction articulaire : différence moyenne standardisée = -0,11 (IC95 % = -0,18 ; -0,05). Les résultats sur ces deux critères de jugement étaient inférieurs aux seuils de pertinence clinique préétablis : -10 mm pour la douleur et -0,37 pour la fonction. De plus, la plupart de ces essais étaient à haut risque de biais. Enfin, un biais de publication a été mis en évidence, susceptible de remettre en cause la réalité de ces éventuels et faibles bénéfices, car plusieurs grands essais cliniques financés par l’industrie n’ont jamais été publiés3-5.
INTERACTIONNISME SYMBOLIQUE : QUEL IMPACT SUR LE TERRAIN COMMUN ET LA RELATION THERAPEUTIQUE ENTRE DES PATIENTS PRESENTANT UN DIABETE DE TYPE 2 ET LEUR MEDECIN TRAITANT ?
Authors: MOREAU A , ZORZI F , GUYON M , SUPPER I , PIGACHE C , DUPRAZ C , FARGE T , PERDRIX C , LAMORT-BOUCHE M
Published: October 2022

Introduction. L’approche centrée sur le patient (ACP) nécessite de créer un « terrain commun » favorable à une relation thérapeutique. Cette relation peut s’exprimer sur la forme d’un interactionnisme symbolique (IS), dans lequel chacun propose à l’autre une « façade » symbolique pour élaborer son « personnage » sur la scène d’une « dramaturgie sociale ». Ceci s’exprime particulièrement lors de la prise en charge de patients ayant une maladie chronique comme le diabète de type 2. Objectif. Décrire les interactions entre les patients vivant avec un diabète de type 2 et leur médecin généraliste (MG). Méthode. Étude phénoménologique interprétative. Entretiens semidirigés auprès de patients vivant avec un diabète de type 2 et auprès de leurs MG. Une analyse comparée et croisée des discours a été conduite. L’analyse s’intéressait aux interactions médecin-patient pour en dégager les « représentations-personnages », le « terrain commun » et son impact sur la relation. Résultats. Dix patients présentant un diabète de type 2 et leurs cinq MG ont été interrogés. Dans trois interactions, le « terrain commun » semblait concordant entre médecin et patient dans un contexte relationnel de confiance et une bonne alliance thérapeutique entre les « personnages ». Dans quatre interactions, le « terrain commun » n’était pas concordant, avec une relation thérapeutique problématique. Dans deux autres interactions, le « terrain commun » semblait moins concordant, mais avec une relation thérapeutique satisfaisante. La dernière interaction mettait en évidence un terrain commun concordant, mais une relation thérapeutique très distanciée. Conclusion. S’intéresser aux « personnages-façades symboliques » que les médecins et les patients « jouent » dans leur interaction interpelle le « terrain commun » et la relation thérapeutique, composantes essentielles de l’approche centrée patient.
Cận sai số Holder toàn cục cho các hàm nửa đại số khả vi
Authors: Hoàng Phi Dũng
Published: October 2022

Trong bài báo này, chúng tôi mở rộng một số kết quả trong [5] của H. V. Hà and P. D. Hoàng về cận sai số Holder toàn cục của tập mức dưới từ lớp hàm đa thức lên lớp hàm nửa đại số. Ngoài ra, chúng tôi đưa ra một số ví dụ cho thấy sự khác biệt về kết quả trong trường hợp hàm nửa đại số so với hàm đa thức.
Về các tập tiếp xúc của hệ ràng buộc
Authors: Nguyễn Văn Tuyên , Hoàng Ngọc Tuấn , Nguyễn Huy Hưng
Published: October 2022

Trong bài báo này, chúng tôi trình bày một số kết quả mới về công thức tính nón tiếp tuyến bậc nhất và tập tiếp xúc bậc hai của các hệ ràng buộc dưới giả thiết về tính calm của ánh xạ tập ràng buộc với nhiễu chính tắc. Các kết quả nhận được mở rộng và cải tiến kết quả tương ứng trong [3], [11] và [12]
Tính chất điểm bất động yếu* của đại số Fourier-Stieltjes trên nhóm compact
Authors: Bùi Ngọc Mười , Trần Thị Thu , Nguyễn Quốc Tuấn
Published: October 2022

Lau và Mah trong [3] đã chỉ ra rằng đại số Fourier-Stieltjes xác định trên một nhóm compact có tính chất điểm bất động yếu*. Tức là, mọi ánh xạkhông giãn trên một tập lồi và compact yếu* đều có điểm bất động. Trong bàibáo này ta trình bày một mở rộng của tính chất nêu trên. Cụ thể là, ta chỉ ra rằng một kết quả tương tự vẫn đúng cho các ánh xạ xấp xỉ không giãn và liên tục theo chuẩn.
MARKETING PLAN OF DAGO DREAMPARK, BANDUNG, WEST JAVA, INDONESIA
Authors: Azzahra Savina , Gohan Purna Wibowo Sun , Fikri Yunus Musabik Firdaus Muhammad , Puspa Ningrum Lintang , Hindun Sinta
Published: October 2022

This research aims to make a marketing plan with a period of one month with the object of observation of the Dago Dreampark destination. This research was conducted at the Dago Dream Park tourist attraction which is located in the Jalan Dago giri Km. 2. 2 Mekarwangi, Pagerwari, Lembang, Kab. West Bandung, West Java 40135. The study was conducted in September-October 2022. The study was conducted using a survey method using a questionnaire to fifty-two tourists as respondents about tourist satisfaction with the Dago Dream Park tourist attraction. in the form of a marketing plan that we designed for a period of one month for the implementation of marketing through social media at Dago Dreampark. In planning this marketing plan, we collect information and analyze business conditions through surveys that we conduct to tourists and interviews that we conduct with Dago Dreampark managers. Furthermore, from this information and data, we determine the target market, develop a marketing strategy, and prepare a detailed marketing budget. As a final step, we determine a marketing plan for one month in September for Dago Dreampark and create content to do digital marketing through social media Instagram.
WINE PRODUCTION MANAGEMENT AT SRIKANDI VINEYARD, JATI AGUNG DISTRICT, SOUTH LAMPUNG REGENCY
Authors: Sidqi Fathir
Published: October 2022

The purpose of this study is to find out an overview of the Srikandi Vineyard business and understand the management of wine production in the Srikandi Vineyard. The activity was held on February 28, 2022 to April 23, 2022 at the Srikandi Jatimulyo Vineyard, Jl. P. Senopati, Gg. Rajawali, Jatimulyo Village, Jati Agung District, South Lampung Regency, Lampung Province. The activities carried out for approximately 2 months (8 weeks) at the Srikandi Jatimulyo Vineyard are related to the management of grape crop production, the products produced are grapes and grape seedlings. However, in this paper, the author focuses on writing reports on production management, namely the preparation of grapevine planting media, replanting old plants into new seedlings, pruning vines, sanitizing the greenhouse environment, and making photosynthetic bacteria (PSB). The conclusion of this activity is that Srikandi Vineyard is a home industry whose output is grapes and grape seedlings, the type of cultivated grapes is imported types of grapes, the greenhouse area of Srikandi Vineyard is 400 m2. Srikandi Vineyard also serves the manufacture of greenhouses and their care until they bear fruit. Grape production management from initial inputs to ready-to-harvest fruits, inputs consist of land, planting media, seeds, fertilizers, and agricultural tools. The process consists of the manufacture of planting media, planting, applying fertilizers, pruning, and fruiting. Harvesting of vines can be carried out after 6 months from the beginning of the seedlings are planted, and the berries are stored in a cooling device so that the berries are kept fresh.
Relación entre patrones histopatológicos con el diagnóstico clínico en pacientes pediátricos con alteraciones renales.
Authors: Sanango Reinoso Wilmer Stalin , Gahona Villegas Junior Rafael , Pérez Galarza Jorge Manuel
Published: October 2022

Introduction: Glomerulopathies in children may not be correlated with the degree of glomerular filtration or the intensity of proteinuria as it occurs in adults. The objective of the present study was to describe the histopathological characteristics of renal biopsies performed in a pediatric population with glomerulopathies and to correlate them with the clinical presentation.
Methods: This observational study was conducted at the Baca Ortiz Pediatric Hospital (Quito) from January 2016 to July 2019. Children with glomerulopathies diagnosed with renal biopsy were included. The variables were clinical diagnosis, histological pattern, age, sex, ethnicity, urea, creatinine, proteinuria, and renal ultrasound. The sample was non-probabilistic. Descriptive statistics were used, and Cramer's V test was used to determine the degree of association.
Results: In 57 cases, 29 (50.9%) were men. The presence of azotemia occurred in 45.6% of the cases. Nephrotic range proteinuria in 47% of cases. The average glomerular filtration rate was 116 ml/min. The most prevalent glomerulonephritis was membranoproliferative (29.8%), with endocapillary and lupus glomerulonephritis accounting for 50% of the sample. Postinfectious glomerulopathy (PGIP) 29 cases (50.9%); Nonproliferative primary glomerulonephritis GMINOP 9 cases (15.8%) and secondary glomerulopathy (GPII) 18 cases (31.6%). There was no association with clinical syndromes (P>0.05).
Conclusions: No relationship exists between histopathological patterns and clinical diagnosis in the sample analyzed in pediatric patients. Primary proliferative glomerulopathies represent little more than half of the renal pathology biopsied.