bluuebunny/crossref_metadata_2025 huggingface dataset:
Surface modification and thermal performance of a graphene oxide/novolac epoxy composite
Authors: Li Shasha , Liu Xi , Fang Changqing , Liu Nailiang , Liu Donghong
Published: June 2018

Functionalized graphene oxide (GO) was successfully modified by grafting 1,3,5-triglycidylisocyanurate (TGIC) onto the surface of GO.
Plasmon-driven surface catalytic reaction of 4-ethynylaniline in a liquid environment
Authors: Liu Yu , Ma Caiqing , Yang Yanqiu , Zhao Yuanchun , Wu Shiwei , Wang Jing , Song Peng , Xia Lixin
Published: June 2018

The mechanism of Ag NP induced dimerization of PEAN was investigated by using SERS spectra. A very interesting phenomenon was discovered, that is where the relative Raman intensities of b2 modes increased either with increasing incident laser power or exposure time.
Molecular dynamic staircases: all-carbon axial chiral “Geländer” structures
Authors: Mannancherry Rajesh , Rickhaus Michel , Häussinger Daniel , Prescimone Alessandro , Mayor Marcel
Published: June 2018

Expanding on previous Geländer models, we designed and characterized two chiral all-carbon Geländer molecules with enhanced thermodynamic stabilities.
Chiral Brønsted acid-catalyzed intramolecular SN2′ reaction for enantioselective construction of a quaternary stereogenic center
Authors: Shimizu Masahiro , Kikuchi Jun , Kondoh Azusa , Terada Masahiro
Published: June 2018

Construction of a quaternary stereogenic center was accomplished through the enantioselective intramolecular allylic substitution reaction of bis-trichloroacetimidate catalyzed by a chiral phosphoramide derivative.
Recent research trends in Li–S batteries
Authors: Kumar Rudra , Liu Jie , Hwang Jang-Yeon , Sun Yang-Kook
Published: June 2018

This review provides important insight into the scientific and practical issues involved with the development of lithium–sulfur (Li–S) batteries.
Recent developments in smart antibacterial surfaces to inhibit biofilm formation and bacterial infections
Authors: Li Xi , Wu Biao , Chen Hao , Nan Kaihui , Jin Yingying , Sun Lin , Wang Bailiang
Published: June 2018

Since their development over 70 years, antibiotics are still the most effective strategy to treat bacterial biofilms and infections.
High responsivity and low dark current nonpolar GaN-based ultraviolet photo-detectors
Authors: Wang Wenliang , Yang Zhichao , Lu Zhenya , Li Guoqiang
Published: June 2018

Nonpolar a-plane GaN-based metal-semiconductor–metal UV PDs, with high responsivity and low dark current, were made from a-plane GaN epitaxial films grown on r-plane sapphire by controlling the dislocation density.
Nobiletin alleviates endometriosis via down-regulating NF-κB activity in endometriosis mouse model
Authors: Wei Xin , Shao Xu
Published: June 2018

Nobiletin exhibits protective potential on inflammation and inhibits the activation of transcription factors nuclear factor-κB (NF-κB). However, its effects on the progression of endometriosis remain unsettled. The present study aimed to explore the in vivo alleviation of nobiletin on endometriosis and its mechanism of action. The mouse model of endometriosis was established and administered with nobiletin. The ectopic lesion size was measured and the hotplate test was performed to assess the amelioration of nobiletin on endometriosis. The expression of proliferation and angiogenesis relevant genes including proliferating cell nuclear antigen (PCNA), vascular endothelial growth factor (VEGF), and E-cadherin was measured by immunostaining and the mRNA expression of proinflammatory mediators including interleukin (IL)-6, IL-1β, tumor necrosis factor (TNF)-α, matrix metalloproteinases (MMP)-1, and MMP-3 was measured by RT-PCR. The change of NF-κB activity in endometriotic cells was evaluated by Western blotting and confirmed by luciferase assay. Administration of nobiletin significantly reduced lesions size and pain in endometriosis mice. Nobiletin significantly altered the expression of PCNA, VEGF, and E-cadherin in ectopic endometrium, as well as the levels of IL-6, IL-1β, TNF-α, MMP-1, and MMP-3. Nobiletin also showed remarkably impairment on the activation of NF-κB in promoting endometriotic cells, likely targeting on the activity of IκB kinases (IKKs). The present study provides the first evidence that nobiletin exerts protection on endometriosis via inhibition the activation of NF-κB, specifically on the activity of IκB kinases.
MiR-362-3p functions as a tumor suppressor through targeting MCM5 in cervical adenocarcinoma
Authors: Wang Dan , Wang Hongyan , Li Yichun , Li Qian
Published: June 2018

Our previous study suggested that minichromosome maintenance protein 5 (MCM5) overexpression was observed in cervical adenocarcinoma and closely associated with advanced clinical stage, more metastatic lymph nodes, present distant metastasis, low histological grade, and poor prognosis. Down-regulation of MCM5 inhibited cervical adenocarcinoma cell proliferation. The purpose of the present study is to search and confirm valuable microRNAs (miRNAs), which target MCM5 to modulate cervical adenocarcinoma cell proliferation. In our results, we found that levels of miR-362-3p expression were reduced in cervical adenocarcinoma tissues and cell lines. Moreover, 3′-UTR of MCM5 had binding site of miR-362-3p through analyzing Targetscan database and miRanda database, and there were an inverse association between miR-362-3p and MCM5 in cervical adenocarcinoma tissues. Furthermore, we verified miR-362-3p directly targeted to 3′-UTR of DCLK1 by luciferase reporter assay, and negatively regulated mRNA and protein expressions of MCM5 by qPCR and Western blot. Then, we conducted gain-of-function study and rescued-function study, and found that miR-362-3p served as a tumor suppressive miRNA to modulate cervical adenocarcinoma cell proliferation through regulating the functional target MCM5. Finally, we analyzed correlations between miR-362-3p expression and clinicopathological characteristics and observed that miR-362-3p low expression was associated with advanced clinical stage and poor prognosis. In conclusion, miR-362-3p is a tumor suppressive miRNA in cervical adenocarcinoma.
Probing insulin sensitivity in diabetic kidney disease: is there a stronger role for functional imaging?
Authors: Granda Michael L. , Amarapurkar Pooja , Fornoni Alessia
Published: June 2018

Clinical and experimental evidence support a cause–effect relationship between altered insulin signaling and development of kidney disease of metabolic and non-metabolic origin. However, the current criteria to measure and/or estimate the insulin resistance (IR) are available as research tool but are very difficult to implement in the clinical practice. Therefore, a better understanding of the key players contributing to IR may lead to the development of new non-invasive tools to assess organ-specific insulin sensitivity (IS). We will therefore first introduce the concept that IR and kidney disease may be causally linked as suggested by clinical and experimental studies. We will then, expand on the potential mechanisms leading to altered renal insulin signaling. After reviewing the limitation of currently available strategies to determine IR, this review article will focus on imaging techniques that could be utilized to determine renal IR and that could be tested to predict kidney disease development and progression.
Comb waveform optimisation with low peak‐to‐average power ratio via alternating projection
Authors: Wang Yan , He Yuliang , Wang Jinjin , Shi Zhibo
Published: June 2018

The active sonar detection performance in shallow water is mainly restricted by the reverberation level. When target echoes are separable from reverberation according to Doppler shifts, comb waveforms with the bed‐of‐nails ambiguity function can achieve reverberation suppression. However, some comb waveforms present significantly low transmitting efficiency measured by the high peak‐to‐average power ratio (PAPR), which may severely affect the detection performance in a noise‐limited scenario. In order to effectively improve their transmitting efficiency, the authors propose an approach of comb waveform optimisation with low PAPR via alternating projection in this study. The main idea is based on designing projection constraint sets and corresponding projection operators to achieve the shaping of comb spectra. Hence, the approach has the capability to make a compromise between the transmitting efficiency and reverberation suppression performance. The PAPR control of geometric comb waveforms is implemented in simulations, which prove the validity of the approach.
Tunable hybrid metal–graphene frequency selective surfaces based on split‐ring resonators by leapfrog ADI‐FDTD method
Authors: Zhai Meng‐Lin , Li De‐ Min
Published: June 2018

A tunable hybrid metal–graphene frequency selective surface (FSS) based on split‐ring resonators at mid‐infrared frequencies is proposed and numerically investigated by an improved leapfrog alternating direction implicit (ADI)‐finite‐difference time‐domain (FDTD) method. The graphene conductivity described by a new closed‐form approximate expression is incorporated into the leapfrog ADI‐FDTD through the vector‐fitting technique and auxiliary differential equation approach. Numerical simulations show that the proposed method has good computational accuracy and higher efficiency compared to conventional FDTD method and analytical solutions. Besides, the transmission and reflection coefficients of the FSS can be effectively adjusted by changing the chemical potential of graphene, the layer number of graphene patch and operating temperature. This work provides a novel method for designing tunable devices for optical plasmonic applications.
Applied magnetic field effect on core mode properties of MFPCF
Authors: Coşkun Seyhan , Öztürk Yavuz , Kahraman Gokalp
Published: June 2018

The work investigates a magnetic fluid filled photonic crystal fibre (MFPCF) at 1557 nm under applied magnetic field. They computed the refractive index change of the MF due to the magnetic field and used it in simulations to find the effective refractive indices of the core and the first cladding modes of the MFPCF. Then, they analytically computed the effective mode area and the confinement loss. The effective refraction index of the core mode increasing by 0.0341% under the applied field of 0–500 Oe, increases the effective mode area by 128% and the confinement loss by 866%. Thus, a rather small change in the effective refractive index gives rise to a rather large change in confinement loss. However, this effect saturates after about 500 Oe because the MF nanoparticles no longer change their magnetic orientation. It is also noteworthy that the confinement loss changes almost linearly with the effective area as the magnetic field change. These results suggest that MFPCF are suitable for a tunable attenuator and a field sensor.
Reduction of 2‐nitrophenol using a hybrid C–Ni nanocomposite as a catalyst
Authors: Ko Jeong W. , Li Jiulong , Suzuki Akira , Takai Kazuyuki , Ko Weon B.
Published: June 2018

Synthesis of hybrid carbon–nickel (C–Ni) nanocomposite was performed with [C60] fullerene and Ni hydroxide in an electric furnace at 700°C for 2 h. The resulting product was characterised by X‐ray diffraction, Raman spectroscopy, scanning electron microscopy, transmission electron microscopy, and electron spin resonance spectroscopy. The catalytic reduction of 2‐nitrophenol using the hybrid nanocomposite was investigated by ultraviolet–visible spectroscopy. Kinetic study showed that reduction of 2‐nitrophenol in the presence of sodium borohydride with the hybrid C–Ni nanocomposite was followed a pseudo‐first‐order reaction law.
Rapid prototyping of PET microfluidic chips by laser ablation and water‐soaking bonding method
Authors: Yin Zhifu
Published: June 2018

The solution to the commercialisation of polymer microfluidic chips lies in the chosen of a low‐cost and concise method. CO2 laser is an excellent tool for ablating arbitrary‐shaped microchannels in most of thermoplastics. However, upheaval area is usually generates along the microchannel due to high temperature during laser ablation process which leads to the difficulty in fully bonding polymer microchannels. In this work, a new bonding method for fully bonding uneven substrates with homogenous surface property was developed based on water‐soaking treatment. To prevent edge separating, an extra laser welding on the lateral of the chip was conducted. The influence of laser current on the width and depth of poly(ethylene terephthalate) (PET) microchannel was investigated. The mechanism of water‐soaking bonding was explained and the parameters of this method were optimised. The experiments showed that PET chip can be fully bonded without any block or leakage and the bonding strength of PET chip can be as high as 3.4 MPa.
Absolute velocity measurements in sunspot umbrae
Authors: Löhner-Böttcher J. , Schmidt W. , Schlichenmaier R. , Doerr H.-P. , Steinmetz T. , Holzwarth R.
Published: June 2018

Context. In sunspot umbrae, convection is largely suppressed by the strong magnetic field. Previous measurements reported on negligible convective flows in umbral cores. Based on this, numerous studies have taken the umbra as zero reference to calculate Doppler velocities of the ambient active region.

Aims. We aim to clarify the amount of convective motion in the darkest part of umbrae, by directly measuring Doppler velocities with an unprecedented accuracy and precision.

Methods. We performed spectroscopic observations of sunspot umbrae with the Laser Absolute Reference Spectrograph (LARS) at the German Vacuum Tower Telescope. A laser frequency comb enabled the calibration of the high-resolution spectrograph and absolute wavelength positions for 13 observation sequences. A thorough spectral calibration, including the measurement of the reference wavelength, yielded Doppler shifts of the spectral line Ti I5713.9 Å with an uncertainty of around 5 m s−1. A bisector analysis gave the depth-dependent line asymmetry.

Results. The measured Doppler shifts are a composition of umbral convection and magneto-acoustic waves. For the analysis of convective shifts, we temporally averaged each sequence to reduce the superimposed wave signal. Compared to convective blueshifts of up to −350 m s−1in the quiet Sun, sunspot umbrae yield strongly reduced convective blueshifts around −30 m s−1. We find that the velocity in a sunspot umbra correlates significantly with the magnetic field strength, but also with the umbral temperature defining the depth of the Ti I5713.9 Å line. The vertical upward motion decreases with increasing field strength. Extrapolating the linear approximation to zero magnetic field reproduces the measured quiet Sun blueshift. In the same manner, we find that the convective blueshift decreases as a function of increasing line depth.

Conclusions. Simply taking the sunspot umbra as a zero velocity reference for the calculation of photospheric Dopplergrams can imply a systematic velocity error reaching 100 m s−1, or more. Setting up a relationship between vertical velocities and magnetic field strength provides a remedy for solar spectropolarimetry. We propose a novel approach of substantially increasing the accuracy of the Doppler velocities of a sunspot region by including the magnetic field information to define the umbral reference velocity.
Optical and UV surface brightness of translucent dark nebulae
Authors: Mattila K. , Haas M. , Haikala L. K. , Jo Y-S. , Lehtinen K. , Leinert Ch. , Väisänen P.
Published: June 2018

Context. Dark nebulae display a surface brightness because dust grains scatter light of the general interstellar radiation field (ISRF). High-galactic-latitudes dark nebulae are seen as bright nebulae when surrounded by transparent areas which have less scattered light from the general galactic dust layer.

Aims. Photometry of the bright dark nebulae LDN 1780, LDN 1642, and LBN 406 shall be used to derive scattering properties of dust and to investigate the presence of UV fluorescence emission by molecular hydrogen and the extended red emission (ERE).

Methods. We used multi-wavelength optical photometry and imaging at ground-based telescopes and archival imaging and spectroscopic UV data from the spaceborn GALEX and SPEAR/FIMS instruments. In the analysis we used Monte Carlo RT and both observational data and synthetic models for the ISRF in the solar neighbourhood. The line-of-sight extinctions through the clouds have been determined using near infrared excesses of background stars and the 200/250 μm far infrared emission by dust as measured using the ISO and Herschel space observatories.

Results. The optical surface brightness of the three target clouds can be explained in terms of scattered light. The dust albedo ranges from ~0.58 at 3500 Å to ~0.72 at 7500 Å. The spectral energy distribution of LDN 1780 is explained in terms of optical depth and background scattered light effects instead of the original published suggestion in terms of ERE. The far-ultraviolet surface brightness of LDN 1780 cannot be explained by scattered light only. In LDN 1780, H2 fluorescent emission in the wavelength range 1400–1700 Å has been detected and analysed.

Conclusions. Our albedo values are in good agreement with the predictions of the dust model of Weingartner and Draine and with the THEMIS CMM model for evolved core-mantle grains. The distribution of H2 fluorescent emission in LDN 1780 shows a pronounced dichotomy with a strong preference for its southern side where enhanced illumination is impinging from the Sco OB2 association and the O star ζ Oph. A good correlation is found between the H2 fluorescence and a previously mapped 21-cm excess emission. The H2 fluorescence emission in LDN 1780 has been modelled using a PDR code; the resulting values for H2 column density and the total gas density are consistent with the estimates derived from CO observations and optical extinction along the line of sight.
Preface
Authors: Rudskoy Andrei
Published: June 2018

Fourth International Conference «Convergence of digital and physical worlds: technological, economic and social challenges» (CC-TESC2018) was held at the St. Petersburg Polytechnic University named after Peter the Great, with the participation of the two strategic partners - the University of Applied Science Wildau (THW, Germany) and St. Petersburg State Economic University (SPSEU) with the support of the Russian Science Foundation (RSF).
On competitive potential of organization under conditions of new industrial base formation
Authors: Ablyazov Timur , Asaul Veronika
Published: June 2018

The world data volume will increase 10 times by 2025 to equal 163 ZettaByte. More than 95% of data will be transmitted in real time by the devices incorporated into network, which is the key feature of new industrial base formation [1]. Even today the information technology gap between economies of the developed and developing countries spells not only a reduction of competitiveness of organizations and individual branches of economy, but the loss of national technological sovereignties. This article considers a system of providing competitiveness of an organization, which is connected with the innovative business model of development and is supported by such a component of entrepreneurial business, as the information technology interaction of entities of social and economic relations.
Digital technologies: new forms and tools of business activity
Authors: Ablyazov Timur , Asaturova Julia , Koscheyev Vadim
Published: June 2018

The digital transformation of business activity is characterized by diffusion of innovative technologies, integration of physical and digital systems. The unprecedented digital revolution has substantially transformed forms of business activity and has given auxiliary options for implementation of new business ideas laying the groundwork for investment climate. The new forms of business activity have different propagation dynamics and they generate in most cases quite different patterns of growth and evolution. The innovative tools and operating models of business activity have got a significant effect on geography and size of prospective market, competitive environment and speed of goods substitution. Changes in global economics in the last ten years have shown that technology companies are the leaders by rates of growth and market capitalization. At the same time, their digital products and developments are key factors in the dynamic development of traditional industries of their economics. The processes of forming and development of business (entrepreneurial) initiative under conditions of introduction of digital economics’ elements in different spheres of socioeconomic interaction have been covered in the article.
Digital economy: backgrounds, main drivers and new challenges
Authors: Akaev Askar , Sarygulov Askar , Sokolov Valentin
Published: June 2018

The industry development over the last hundred years has had a huge impact on the development of technological infrastructure and life change. Three main components of this development are related to personalization: a car as a personal vehicle and greater personal freedom; a personal computer as a means of intellectual autonomy; a personal phone as a means of freedom of communication and access to information. These three development factors significantly changed the employee psychology and created the conditions for diffusion of qualitatively new, synthesized (cyber-physical) technologies that became the basis of the Industry 4.0 and the Internet of Things – two main working concepts of industrial and infrastructural development for the next 20 years. The conventional or classical industrial systems that are dominant to the present day have mainly been based on the principles of human muscle energy replacement, but the technological changes of our days raise the question of the substantial scale of displacement of the living manpower both in production and in management and services. The process of technological and industrial transformation that has already begun will inevitably lead to the transformation of social and economic systems, and here the key problem will not only be the provision of a new quality of economic growth, but also the solution of the employment problem interfacing a new technological platform, the information and social infrastructure of society.
The Analysis of industrial cooperation models in the context of forming digital economy
Authors: Babkin Aleksandr , Plotnikov Vladimir , Vertakova Yulia
Published: June 2018

Approaches which enable improving the efficiency of industrial enterprises functioning in the context of forming digital economy are discussed in the article. In contrast to the traditional analysis of this problem on macro- (national economy in general, creating a favorable institutional environment for industrial development and digitalizing of economy) or micro- (development of recommendations for implementing digital technologies in manufacturing and management subsystems of industrial enterprises) levels, the authors consider a meso-level. Studies undertaken have made it possible to come to a conclusion that current digitalization of both enterprises and industry in total determines the changes of industrial cooperation models. It has been indicated that significant opportunities for effective development of industry are connected with forming integrative groups of cooperation-interactive enterprises. Such models of interaction as outsourcing, cluster and strategic alliance have been considered and their pros and cons have been revealed. Recommendations on designing cooperation interaction between industrial enterprises have been formulated. The design is oriented on improving the effectiveness of using resources and reducing risks.
Supporting connectivity of VANET/MANET network nodes and elastic software-configurable security services using blockchain with floating genesis block
Authors: Busygin Alexey , Kalinin Maxim , Konoplev Artem
Published: June 2018

This paper considers the tasks of supporting the connectivity of nodes in communication networks of unmanned transport (VANET/MANET-networks). High dynamics, decentralization and absence of hierarchy in the networks of this type actualize the task of supporting the connectivity of nodes with software-configurable security services, providing the network protection. It is offered to use a Blockchain technology based system for VANET/MANET network topologyand authentication data distribution and storage. The issue of unlimited blockchain growth preventing this method from being implemented in VANET/MANET networks is considered. The existing solutions of this issueare analyzed and drawbacks are identified. A notion of blockchain with floating genesis block is introduced and its advantages over similar ideas are demonstrated thus allowing it to be used to resolve the issue of continuously growing blockchain within the systems with stalingtransactions as a whole and in VANET/MANET networks in particular.
Foundation architecture of telemedicine system services based on Health 4.0 concept
Authors: Dubgorn Alisa , Kalinina Olga , Lyovina Anastasia , Rotar Oksana
Published: June 2018

Telemedicine as an application area of the modern medicine is flourishing supported by the corresponding technologies development. Development of telemedicine technologies is one of the main trends in digitalization of health care service put into practice within the Health 4.0 concept. Implementation of telemedicine systems is particularly topical for countries possessing a great territory, due to which the problem occurs to provide equal access to specialized and hi-tech medical aid for all inhabitants in the country. Creation of the effective telemedicine system for rendering medical aid to patients in remote locations requires a system approach to engineering and implementation of such system. Represented in the article is a structure of the telemedicine system engineering and implementation project with the use of service-oriented approach to simulation of social-economic systems, as well as requirements to upper level services of such system within the first stage of the project.
Computer modelling of fire resistant solutions for structures in high-rise buildings with using of new fire-retardant materials
Authors: Gravit Marina , Gumerova Eliza , Lulikov Vladimir
Published: June 2018

The article describes possibilities of computer modeling of fire resistance for structures in high-rise buildings, which include new fire-resistant plaster compositions. As an example of program complex, “Sofistik” (Germany) was chosen for the calculation of reinforced concrete structures of tier buildings. The characteristics of fire protection compounds and their regulation, which are usually used, also are shown. According to the new code “Highrise buildings and complexes. Fire safety requirements”, limits of fire resistance for walls of not less than 240 minutes. Skyscraper “Lakhta center” with a height of 462 m and limits of fire resistance of load-bearing reinforced concrete structures 180 and 240 minutes is built up in Russia. The article investigates the means of fire protection in the business center. Moreover, modern form of cladding in Mada Residences building (Dubai, UAE) is concerned to make some conclusions about future fire resistant solutions.
Application of additive technologies for synthesis of titanium alloys of Ti-Al, Ti-Al-Nb systems of elemental powders
Authors: Grigoryev Alexey , Polozov Igor , Popovich Anatoliy , Sufiyarov Vadim
Published: June 2018

Additive technologies are one of the drivers for development of new industrial revolution. For developing additive production it is necessary to expand the nomenclature of materials used in the form of powders. One of the ways for synthesizing new alloys in additive technologies is applying a mixture of powders as primary components; the powders correspond in their composition to the given alloy. The technology of selective laser melting enables synthesizing the necessary alloy by means of layer by layer melting of a powder mixture. A study of the process of Ti-5Al and Ti-6Al-7Nb titanium alloys synthesis of elemental powders by means of selective laser melting was undertaken in this work. Microstructure, chemical composition, mechanical properties of the synthesized alloys were studied and also the influence of thermal processing on the microstructure of the Ti-6Al-7Nb alloy obtained of elemental powders was explored.
Smart Hospital concept and its implementation capabilities based on the incentive extension
Authors: Ilyashenko Oksana , Ilin Igor , Kurapeev Dmitry
Published: June 2018

Currently, the health care as one of the priority development areas for the state requires special attention in the transition to the innovative management models based on the use of advanced medical concepts and digital technologies. Therefore, the transition to the SmartHospital model and the formation of an appropriate architectural solution become actual for health organizations which strategic task is the transition to the digital space and strengthening their positions in the medical services market. Prior to starting the development of the Smart Hospital architectural model as applied to the specific health organization, it is advisable to use a reference model that will take into account the basic business and IT requirements of the organization, limits and used technologies. The creation of the reference SmartHospital architectural solution is preceded by a preparatory stage that allows revealing the architecture and limit requirements. The article proposes the incentive extension on the basis of which the requirements and limits are formulated for the reference model of the SmartHospital architectural solution.
Simulating combustion processes based on digital technologies
Authors: Kadyrov Marsel , Khabarova Maria , Khabarov Alexander , Trinchenko Alexei
Published: June 2018

The thermal power plants (TPP) make a basis of power-generation industry of the majority of countries. The global growth of power consumption and the policy of energy-saving demand to increase the efficiency of plants operation, which is, among others, determined by the technical level of steam-generating units. The up-to-date digital technologies make it possible to assess the efficiency of boiler furnace operation at the stage of boiler unit designing, its reconstruction or retrofitting and upgrading. Developed in the article are the algorithm, mathematic model and computer program of calculating diffusion-kinetic process of combustion of D-grade Donetsk coal in the coal-dust flame of boiler Е-230-14,0-520. The assigned tasks have been solved by using theoretical methods of analysis, the capabilities of devices of computer-aided calculations have utilized for visualization of results. The considered digital approach to solving technical tasks makes it possible to meet the current and future challenges.
Estimation of applicability of modern neural network methods for preventing cyberthreats to self-organizing network infrastructures of digital economy platforms,
Authors: Kalinin Maxim , Krundyshev Vasiliy , Zubkov Evgeny
Published: June 2018

The problems of applying neural network methods for solving problems of preventing cyberthreats to flexible self-organizing network infrastructures of digital economy platforms: vehicle adhoc networks, wireless sensor networks, industrial IoT, “smart buildings” and “smart cities” are considered. The applicability of the classic perceptron neural network, recurrent, deep, LSTM neural networks and neural networks ensembles in the restricting conditions of fast training and big data processing are estimated. The use of neural networks with a complex architecture– recurrent and LSTM neural networks – is experimentally justified for building a system of intrusion detection for self-organizing network infrastructures.
Twisted particles as a new tool to study micro world phenomena and processes
Authors: Mayorova Anna
Published: June 2018

Twisted or vortex particles are a new powerful tool to study atomic and molecular processes as well as phenomena that occur at the level of nano-objects. The main feature of such particles is that they carry a non-zero projection of orbital angular momentum along the beam propagation direction. The process of twisted electron scattering from diatomic molecule targets has been studied in this paper for the first time. The Yukawa potential is selected as a model potential. Numerical calculations are carried out for the case of scattering from a hydrogen molecule H2.
Conceptual model of information support for taking decisions
Authors: Nurulin Yury , Skvortsova Inga
Published: June 2018

The modern society is characterized by qualitative changes in the volumes, composition and significance of collected and processed data. This data reflects the condition of the real and virtual world surrounding people and it is used for respective impact on the real and virtual world. All this requires theoretical generalizations that form a single conceptual platform as for managers working with the real world and for knowledge management professionals who work with the virtual world. The traditional model of taking decisions in management indirectly reflects the significance of knowledge and other elements of the virtual world for taking effective decisions which have impact on the real world. However the process of forming knowledge is not reflected in these models. Traditional models of knowledge management mainly concentrate on the internal transformation processes “data-information-knowledge-wisdom” which further are used for taking decisions.
Architecture of homeostatic security control for digital manufacture systems based on software-defined networks
Authors: Pavlenko Evgeny , Zegzhda Dmitry
Published: June 2018

The authors have offered the homeostatic control system architecture for digital manufacture security based on the software-defined network technology. We have highlighted the development features of digital manufacture systems and defined the technology advantages of software- defined networks, which allow these networks to be successfully applied with flexible and adaptive topology for a highly efficient new generation of cyber-physical systems. We have also described the main operating principles of software-defined networks in digital manufacture systems. A description of homeostatic security control technology, which includes a combination of engines to provide stability of the system’s internal environment and structural and functional resistance to external disturbances, is provided. We have proposed and described in detail the homeostatic security control system architecture including three generalized components: monitoring unit, decision-making unit, protection and control unit.
Mathematical model for the evaluation of risk of emergency situations at a dangerous technical object based on artificial neural networks
Authors: Peganov Nikolay , Tumanov Aleksandr , Tumanov Vladimir
Published: June 2018

In the work performed adaptation of artificial neural networks in modern security systems potentially dangerous technical objects — high-rise buildings as tools for assessing and forecasting in management decision. The study obtained the main scientific results: the mathematical model of risk assessment of man-made emergencies based on artificial neural networks; the mathematical model, adapted to the cumulative model of development technogene emergency-fire; provided risk assessment technique manmade emergencies based on artificial neural networks; represented private man-made fire risk assessment methodology using artificial neural networks.
The model of system predicting with the use of dynamic arrangement schemes
Authors: Pirogova Oksana , Plotnikov Vladimir , Prolubnikov Andrey
Published: June 2018

The basic problems are considered in the paper connected with solving the problems of forecasting development of enterprises in the conditions of growth of volumes and intensity of information flows in consequence of digitalization of economic processes. The aspects of using a cost approach and also life cycle models of enterprises in the tasks of building the system of planning and predicting activity are considered. An approach to forecasting development of an enterprise on the basis of a dynamic model of the cost growth is proposed by the authors. As the main general indicator fundamental cost of an enterprise is considered, which includes four basic elements. A principle which takes into account dynamic cosubordination of basic indicators of growth of the fundamental enterprise cost is accepted as a basis for the predicting model. A variant of a structure of an adaptive model of dynamic cosubordination of basic indicators is suggested; the structure changes depending on the stage of the life cycle. The represented approach enables taking into account contradictory requirements to the choice of key indicators of development, changing at different stages of the life cycle, and also estimating and predicting the activity of an enterprise from unified positions.
Antigravity ESD – double-balloon-assisted underwater with traction hybrid technique
Authors: Sharma Sam , Hiratsuka Takahiro , Hara Hisashi , Milsom Jeffrey
Published: June 2018

Background and study aims Complex colorectal polyps or those positioned in difficult anatomic locations are an endoscopic therapeutic challenge. Underwater endoscopic submucosal dissection (UESD) is a potential technical solution to facilitate efficient polyp removal. In addition, endoscopic tissue retraction has been confined to limited methods of varying efficacy and complexity. The aim of this study was to evaluate the efficiency of a unique UESD technique for removing complex polyps using double-balloon-assisted retraction (R).

Materials and methods Using fresh ex-vivo porcine rectum, 4-cm polyps were created using electrosurgery and positioned at “6 o’clock” within an established ESD model. Six resections were performed in each group. Underwater techniques were facilitated using a novel double-balloon platform (Dilumen, Lumendi, Westport, Connecticut, United States).

Three different polypectomy methods were compared: 1. UESD with retraction (UESD-R), 2. UESD, 3. Traditional cap-assisted ESD technique.

Results UESD-R had a significantly shorter total procedural time than cap-assisted ESD and UESD alone (24 vs. 58 vs. 56 mins). UESD-R produced a dissection time on average of 5 minutes, attributed to the retraction provided. There was also a subjective significant reduction in electrosurgical smoke with the underwater techniques contributing to improved visualization.

Conclusions Here we report the first ex-vivo experience of a unique double-balloon endoscopic platform optimized for UESD with tissue traction capability. UESD-R removed complex lesions in significantly shorter time than conventional means. The combined benefits of UESD and retraction appeared to be additive when tackling complex polyps and should be studied further.
Standards in der Nachbehandlung nach vorderem Kreuzbandersatz im deutschsprachigen Raum
Authors: Valle Christina , Hirschmüller Anja , Schmitt-Sody Marcus , Haller Bernhard , Keller Matthias , Schoch Wolfgang , Hoffman Helmut , Minzlaff Philipp
Published: June 2018

Einleitung Die Nachbehandlung nach Rekonstruktion des vorderen Kreuzbandes (VKB) ist nach wie vor ein kontrovers diskutiertes Thema. Die existierenden Nachbehandlungsschemata unterscheiden sich teils erheblich, unter anderem da bei einigen Aspekten noch kein Nachweis einer optimalen Vorgehensweise existiert. Das Ziel dieser Befragung war es zu untersuchen, wie die Nachbehandlung nach VKB-Ersatz

im deutschsprachigen Raum von Ausbildern für arthroskopische Kniegelenksoperationen mit besonderer Expertise empfohlen wird und dies mit der aktuellen Literatur zu vergleichen.

Material und Methoden Es wurde eine strukturierte anonyme Online-Umfrage an Instruktoren der Gesellschaft für Arthroskopie und Gelenkchirurgie (AGA) zur Nachbehandlung nach operativer Versorgung der isolierten Ruptur des vorderen Kreuzbandes durchgeführt. Der Fragebogen enthielt 23 geschlossene Fragen mit teils mehrfacher Antwortmöglichkeit.

Ergebnisse Bei 218 befragten Operateuren konnten 117 vollständig beantwortete Fragebögen analysiert werden. 96,5 % der Operateure geben die Vollbelastung nach spätestens 4 Wochen frei, 52,6 % limitieren die Beugung und 9,7 % die Streckung des Kniegelenks nach der Operation. Eine Orthese wird von 82,8 % verordnet, überwiegend mit einem harten Rahmen. In den ersten 6 Wochen werden v. a. isometrisches Training und Übungen in geschlossener Kette empfohlen. Fahrradfahren wird von 78,5 % und Autofahren von 86,2 % der Befragten spätestens nach 6 Wochen wieder erlaubt.

Die Mehrheit der befragten Operateure erlaubt Joggen (65,5 %) und Sprungsportarten (67,0 %) nach 3 Monaten, Alpinskifahren (53,0 %) sowie Kontakt- und Mannschaftssport wird oftmals nach 12 Monaten freigegeben (55,2 % und 46,2 %). 82,6 % der Befragten wünschen sich eine praxistaugliche Return-to-sport-Testbatterie.

Schlussfolgerung Auch bei erfahrenen Kreuzbandoperateuren kommen nach wie vor viele unterschiedliche postoperative Nachbehandlungschemata und -empfehlungen zur Anwendung. Oft entspricht die gängige Praxis dabei nicht den Empfehlungen der aktuellen Literatur. Obwohl der Einsatz von Orthesen keinen nachweislichen Vorteil bringt, schützen die Mehrzahl der Operateure das von ihnen operierte Gelenk mittels Hartrahmenschiene und die Trainingsempfehlungen entsprechen oft nicht der Evidenz.
Gibt es DAS Studium für MTRA?
Authors: Piede Danny
Published: June 2018

Der Beruf des Medizinisch-technischen Radiologieassistenten (MTRA) beruht auf dem MTA-Gesetz (MTAG) aus dem Jahr 1993. Auch die Ausbildungs- und Prüfungsverordnung (MTA-APrV) ist längst überholt. Aus Ihrer beruflichen Erfahrung wissen Sie, dass die im Gesetz und der Verordnung beschriebenen Tätigkeiten und Ausbildungsinhalte längst nicht mehr mit der Arbeitsrealität einer bzw. eines MTRA von heute übereinstimmen. Durch die stetige Weiterentwicklung von radiologischen Technologien und neuesten Erkenntnissen aus Wissenschaft und Forschung kommt es zu einer Verschiebung von Aufgaben sowohl im ärztlichen Bereich als auch im Bereich des Assistenzberufes. Welche Möglichkeiten gibt es nun also für Sie, sich in Deutschland akademisch weiterzubilden?
Wearing Colored Glasses can Influence Exercise Performance and Testosterone concentration?
Authors: Londe André , Marocolo Moacir , Marocolo Isabela , Fisher James , Neto Octavio , Souza Markus , da Mota Gustavo
Published: June 2018

Perception of red color is associated with higher testosterone concentration and better human performance. Thus, we evaluated the acute effects of wearing colored-lens glasses on the YoYo intermittent endurance exercise test 2 (YoYoIE2) performance indicators and testosterone concentration. Ten soccer players performed three YoYoIE2 (counterbalanced crossover) wearing colorless (control), blue- or red-lensed glasses (2–4 days of rest in between). YoYoIE2 performance did not differ among the trials (p>0.05), but blood testosterone increased post-exercise in red compared to red baseline (red=14%, effect size=0.75). Analysis showed faster heart rate recovery (p<0.05) at 1 min post-test for blue compared to red lenses. Rating of perceived exertion and blood lactate concentration did not differ (p>0.05) among the trials. Wearing red-colored lenses during high-intensity intermittent exercise increased testosterone concentration, but do not influence performance.
The Occurrence of Repeated High Acceleration Ability (RHAA) in Elite Youth Football
Authors: Serpiello Fabio , Duthie Grant , Moran Codey , Kovacevic Damian , Selimi Erch , Varley Matthew
Published: June 2018

The aim of the present study was to investigate the occurrence of Repeated High-Acceleration Ability (RHAA) bouts in elite youth football games using 10-Hz GPS devices and two relative thresholds derived from players’ actual maximal acceleration. Thirty-six outfield soccer players (age 14.9±0.6 years) participated in the study. Players wore 10-Hz GPS units during 41 official games. High accelerations were defined as efforts commencing above a threshold corresponding to 70% (T70%) or 80% (T80%) of the average 5-m acceleration obtained during a 40-m sprint test; RHAA bouts were defined as ≥3 efforts with ≤45 s recovery between efforts. Results were analysed via generalised linear mixed model and magnitude-based inferential statistics. On average, 8.0±4.6 and 5.1±3.5 bouts were detected in an entire game using T70% and T80%, respectively. When all positions were analysed together, there was a very-likely small difference in the number of RHAA bouts between first and second half for T70% and T80%, respectively. RHAA bouts occur frequently in elite youth football, with small differences between halves and between playing positions within the first or second half in most variables assessed.
Reaction between Chalcones, 1,3-Dicarbonyl Compounds, and Elemental Sulfur: A One-Pot Three-Component Synthesis of Substituted Thiophenes
Authors: Adib Mehdi , Rajai-Daryasarei Saideh , Pashazadeh Rahim , Jahani Mehdi , Amanlou Massoud
Published: June 2018

A simple and atom-economic synthesis of highly substituted thiophenes is demonstrated. Heating a solution of a chalcone and a ­linear/cyclic 1,3-dicarbonyl compound with elemental sulfur in CH3CN in the presence of NEt3 at 80 °C afforded the corresponding substituted thiophenes in good to excellent yields.
Hepatic Dendritic Cells, the Tolerogenic Liver Environment, and Liver Disease
Authors: Dou Lei , Ono Yoshihiro , Chen Yi-fa , Chen Xiao-ping , Thomson Angus W.
Published: June 2018

The unique liver immune microenvironment favors resistance to inflammation that promotes normal physiological function. At the same time, it endows the liver with tolerogenic properties that may promote pathological processes. Hepatic dendritic cells (HDCs) initiate and orchestrate immune responses depending on signals they receive from the local environment and are thought to contribute to liver tolerance. Thus, HDCs facilitate impaired T cell responses that are observed in persistent hepatitis C virus (HCV) infection, hepatocellular carcinoma progression, and liver allograft transplantation. HDCs also participate in anti-inflammatory responses in liver ischemia–reperfusion injury (IRI). Moreover, they promote the regression of fibrosis from various fibrogenic liver injuries. These findings suggest that HDCs regulate intrahepatic immune responses, allowing the liver to maintain homeostasis and integrity even under pathological conditions. This review focuses on the tolerogenic properties of HDCs based on recent research and in relation to liver disease pathogenesis and its therapy.
Minimally Invasive Management of Abdominal Trauma
Authors: Ritter Kaitlin , Claridge Jeffrey , El-Hayek Kevin
Published: June 2018

Management of traumatic abdominal injuries has traditionally relied upon a combination of systematic physical examination, image-guided evaluation, clinical judgment, and, when necessary, maximally invasive surgical intervention. Advances in the fields of interventional radiology, endoscopy, and laparoscopy have altered these traditional treatment algorithms. As growth of these techniques continues, an increasing number of minimally invasive strategies are available to clinicians for the management of abdominal trauma. Here reviewed is a brief overview of minimally invasive strategies for the management of non–solid organ abdominal trauma with a focus on new, minimally invasive diagnostic and treatment tools.
Role of Image-Guided Percutaneous Drainage in Pancreatic Collections
Authors: Samadi Katayoun , Arellano Ronald
Published: June 2018

Acute pancreatitis is one of the major gastrointestinal conditions that lead to around 300,000 hospital admissions per year in the United States. While mild inflammation of the pancreas is often managed conservatively, progression of the disease process to necrosis significantly increases the overall morbidity and mortality and often requires surgical or other interventional techniques for management. The purpose of this review is to describe the role of percutaneous drainage for the management of complicated pancreatitis.