bluuebunny/crossref_metadata_2025 huggingface dataset:
LABORATORY DIAGNOSTIC OF HUMAN BABESIOSIS
Authors: Kukina I. V. , Zelya O. P. , Karan L. S.
Published: February 2020

Human babesiosis caused by parasitic protozoan Babesia spp. is sporadic zoonotic vector-borne infection. The course of babesiosis and prognosis depend on the type of pathogen and on the patient’s immunological status. Significance this disease is a severe, often fatal course with immunocompromissed patients resembling complicated falciparum malaria. In Europe to date, more than 50 cases of confirmed human babesiosis have been reported in most cases caused by Babesia divergens. Possible there are unrecognized cases. Pathogen is an obligate intraerythrocyte parasite of vertebrate animals. The organism is transmitted from animal to man through bite of Ixodidae tick. Asexual reproduction of the parasite occurs in a vertebrate host. The pathogenesis of babesiosis is caused by the destruction of host cells. Intensive haemolysis of red blood cells leads to the development of haemolytic anemia, haematuria, jaundice, and polyorgan failure may develop. The clinical manifestations of the disease are nonspecific. Detection of intraerythrocyte parasites in blood smears stained Gimsa-Romanovsky confirms the proposed diagnosis. Blood smears and some laboratory signs from fatal cases were analyzed in the Reference-centre of E. I. Martsinovskiĭ Institute. Original microphotographs B. divergens are shown. The main morphological forms of the parasite are shown. In addition to the well-known tetrades of parasites «Maltese Cross», for the first time, the parasites dividing into 6 interconnected trophozoites - “sextet” - were found. Originally, the invasion of Babesia in a normoblast is shown. An unusually high multiple invasion (14 parasites) of erythrocytes is noted. Because the patients, initially, were incorrectly diagnosed with malaria, the differential diagnosis of Babesia with Plasmodium is described step-by-step. It is important, since the treatment with antimalarial drugs is ineffective. Deviation laboratory signs are discussed. Complex morphological characteristics allowed us to speciated the parasites as B. divergens. DNA was detected in the sample with specific primers Bab di hsp70F/Bab di hsp70R and the probe Bab di hsp70P. The sequence demonstrated 99-100% and 98% similarity to the 18S rRNA gene fragment of B. divergence and Babesia venatorum, respectively. Molecular biological and serological methods of laboratory diagnosis of babesiosis are considered.
Cited analysis of articles with keywords of ‘Instructional Design’ in DOAJ
Authors: Yaman Feriha Emel , Ozcinar Zehra
Published: February 2020

The purpose of this study was to provide 158 Open-Access Magazine Guides, 158 of which were found in the magazines covered by the Directory of Open Access Journal (DOAJ; from the beginning until the end of 2016) subjects; number of authors; number of citations; distribution of keywords; and distribution of magazines by country, author and citations. The authors of the most cited articles, the number of citations and years, the number of citations the authors have taken on a country basis, and page numbers and bibliographic numbers are examined. It is believed that in the current literature there is only one study on instructional design and it is necessary and important because of its contribution to the field. The fact that the articles published in the electronic magazines published in the DOAJ Open Access Guide used the term ‘Instructional Design’ in the keywords to reach the relevant articles constitutes the limitation of this study. This research is a quantitative study in the screening model because it is a research approach that identifies the situation that exists in the past and the present. Content analysis was done because the articles were examined in terms of content. The titles were searched, and the obtained data were uploaded to the spreadsheet program and the tables were created. The data were analysed by interpreting the tables by calculating the frequencies and percentages.
Keywords: Citation analysis, DOAJ, instructional design, open access.
Peran Guru Dalam Mendidik Akhlak Anak Usia Dini (Studi Kasus di RA Miftahul Ulum Ragang Kecamatan Waru Pamekasan)
Authors: Saedah Saedah , Masruroh Waqiatul , Aziz Thorik
Published: February 2020

Hasil penelitian menunjukkan bahwa: pertama, cara guru dalam mendidik akhlak anak di RA Miftahul Ulum Desa Ragang  Kecamatan Waru Kabupaten Pamekasan. a) memberikan contoh dan teladan yang baik kepada anak. b) memberi keteladanan sejak dini. c) mendidik melalui ucapan dan perbuatan. . Kedua, faktor- faktor pendukung dan penghambat yang di hadapi guru dalam mendidik ahkhlak anak di RA Miftahul Ulum Desa Ragang Kecamatan Waru Kabupaten Pamekasan. faktor pendukungnya adalah a) karena memang sudah kewajiban dan tanggung jawab seorang guru. b) dukungan dari keluarga. c) lingkungan sekolah. Sedangkan faktor penghambatnya adalah: a) karena kesibukan orang tua. b) lingkungan. c) media massa. Ketiga: cara mengatasi faktor penghambat yang di hadapi guru dalam mendidik akhlak anak di RA Miftahul Ulum Desa Ragang  Kecamatan Waru  Kabupaten Pamekasan. a) ketika anak kurang kasih sayag dari orang tua, guru harus memberi perhatian yang lebih kepada anak didiknya. b) orang tua haus mengawasi anak didiknya agar tidak salah dalam bergaul. c) ketika anak sedang menonton TV orang tua harus mengusahakan agar anak tidak menonton hal-hal yang berdampak negatif.
Pembubaran Korporasi yang Melakukan Tindak Pidana Pencucian Uang dan Tindak Pidana di Bidang Lingkungan Hidup
Authors: Safitri Fatimah Dwi
Published: February 2020

Indonesia menjamin setiap warga negara Indonesia memiliki hak untuk hidup sejahtera lahir dan batin, bertempat tinggal, dan mendapatkan lingkungan hidup yang baik dan sehat serta berhak memperoleh pelayanan kesehatan. Namun, jumlah kerusakan lingkungan hidup yang terjadi kian meningkat tiap tahun. Banyak kasus lingkungan hidup yang hanya menyasar pelaku fisik saja sedangkan korporasi yang mendapatkan manfaat dari kerusakan lingkungan serta merupakan intellectual actor malah lolos begitu saja. Keadaan yang demikian tersebutlah yang mendorong pentingnya upaya multi door yaitu melalui pendekatan pencucian uang supaya actor intellectual yang berada di balik layar dapat terungkap dan diadili sesuai dengan perbuatannya. Bentuk pidana tambahan yang dapat dijatuhkan berupa pembubaran korporasi menjadi faktor penting terciptanya efek jera supaya korporasi yang telah melakukan perusakan lingkungan tidak berani melakukan perusakan lingkungan kembali. Tujuan peneletian ini adalah untuk mengetahui bagaimana penjatuhan pidana tambahan berupa pembubaran terhadap korporasi yang melakukan tindak pidana pencucian uang dan tindak pidana lingkungan hidup. Untuk melakukan penelitian ini, tipe penelitian yang digunakan oleh penulis adalah tipe yuridis normatif yang nantinya akan menghasilkan sebuah penjelasan yang sistematis mengenai aturan hukum yang mengatur kategori hukum tertentu yang terdapat isu hukum di dalamnya.
Penyalahgunaan Senjata Api Pelaku Militer Dan Pelaku Sipil
Authors: Maf’ula Kansa Ahsani
Published: February 2020

Permasalahan mengenai penyalahgunaan senjata api yang kerap terjadi di tengah-tengah masyarakat. Senjata api merupakan benda penting bagi anggota kepolisian juga anggota militer yang digunakan untuk menjaga keamanan Indonesia. Namun dalam kenyataannya, senjata api tersebut disalahgunakan oleh banyak pihak, termasuk pihak militer bahkan masyarakat sipil. Masyarakat sipil memang diperbolehkan untuk memiliki senjata api, namun harus memenuhi persyaratan yang sudah ditentukan oleh undang-undang untuk mendapatkan izin kepemilikan. Dalam penelitian ini dijelaskan mengenai penyalahgunaan senjata api yang dilakukan oleh anggota militer dan masyarakat sipil dalam satu rangka kejadian. Pada umumnya, tindak pidana yang dilakukan oleh masyarakat sipil yang tunduk dengan lingkungan peradilan umum dan anggota militer yang tunduk pada peradilan militer, diperiksa secara koneksitas. Metode penelitian yang digunakan adalah doctrinal research atau normatif. Sedangkan pendekatan yang digunakan dalam penelitian ini adalah pendekatan perundang-undangan (statute approach), pendekatan kasus (case approach), dan pendekatan konseptual (conceptual approach). Dalam penelitian ini digunakan tiga putusan pengadilan dengan kasus yang sama, namun dengan pelaku yang tunduk pada lingkungan peradilan yang berbeda. Dimana salah satunya merupakan anggota militer yang tunduk pada peradilan militer, dan yang lainnya adalah masyarakat sipil yang tunduk pada peradilan umum. Penyalahgunaan senjata api oleh warga sipil terkait dengan izin kepemilikan, jadi harus lebih ketat. Kemudian untuk anggota militer, perlunya penegakan disiplin yang lebih baik lagi dan juga pemahaman bagi anggota militer. Selain itu perlunya penegakan undang-undang mengenai perkara koneksitas agar lebih efektif dan efisien.
EVALUASI PENDAPATAN MASYARAKAT UNTUK PENINGKATAN KESEJAHTERAAN MASYARAKAT PASCA BENCANA BANJIR LAHAR DI KALI PUTIH KABUPATEN MAGELANG
Authors: Kumalawati Rosalina , Prasaja Ahmad Syukron
Published: February 2020

ABSTRAK

Penelitian ini bertujuan untuk: (1) Melakukan evaluasi pendapatan masyarakat pasca kejadian bencana banjir lahar. (2) Mengetahui tingkat kesejahteraan masyarakat. (3) Mengetahui sebaran pendapatan masyarakat pasca bencana banjir lahar secara spasial Metode yang digunakan untuk mengetahui pendapatan masyarakat, dan tingkat kesejahteraan masyarakat adalah melalui Focus Group Discussion (FGD) dan survey lapangan. Hasil penelitian menunjukkan bahwa pendapatan masyarakat yang berprofesi sebagai penambang pasir, batu dan kerikil dapat diidentifikasi melalui segmentasi banjir lahar Kali Putih yang terdiri dari Zona Produksi Lahar, Zona Transportasi Lahar dan Zona Sedimentasi Lahar. Hasil penelitian menunjukkan bahwa pPenambang pasir mendapat keuntungan maksimal Rp. 2.250.000 dalam sebulan, penambang batu Rp. 7.500.000 dalam sebulan dan penambang kerikil Rp. 2.250.000 dalam sebulan. Tingkat kesejahteraan masyarakat cenderung meningkat ketika masyarakat memutuskan mengubah profesi. Masyarakat yang sebelumnya berprofesi sebagai petani dalam sebulan maksimal hanya menghasilkan Rp. 2.500.000, buruh tani, buruh serabutan, dan buruh pasir masingâ€“masing Rp. 1.000.000,-. Banjir lahar bagi para petani dan buruh tani telah merusak lahan pertanian tempat mereka menyambung hidup, sementara bagi buruh pasir dan penambang merupakan limpahan berkah karena sebagai mata pencaharian. Tidak sedikit jumlah petani, buruh tani, buruh serabutan, dan buruh pasir yang mengubah profesi mereka menjadi penambang pasir, batu dan atau kerikil. Kata Kunci: Banjir Lahar, Profesi, Evaluasi Pendapatan, Tingkat Kesejahteraan
MODEL KONSERVASI SUMBERDAYA AIR SEBAGAI UPAYA MEMPERTAHANKAN KEBERLANJUTAN AIR DI SUB DAS AEK SILANG
Authors: Sihotang Irwan Valentinus , Sudarmadji Sudarmadji , Purnama Setyawan , Baiquni Baiquni
Published: February 2020

ABSTRACT

Continuous availability of water as a basic requirement for survival and for the purposes of production so need to be maintained. The availability of water resources is strongly influenced by environmental and natural resource management is done by humans. Water resource conservation efforts through the increased role of the parties is expected sustainability of water can be maintained. The research objective is to formulate a model of conservation of water resources and efforts needed for water sustainability can be maintained. Data were collected using questionnaires and interviews, and then analyzed descriptively by using a technique AHP (Analytical Hierarchy Process). The results of the analysis with AHP technique showed that the main priority of the alternative strategy of water resources conservation activities is to preserve water (38.70%). The effort to preserve water is technically civilian conservation, forest and land rehabilitation (RHL), control the use of water, maintenance of water resources and coaching/mentoring for communitie. Keywords: Sustainable water, Water resource conservation, AHP, Preserve water
PEMETAAN BAHAYA BANJIR KABUPATEN HULU SUNGAI TENGAH PROVINSI KALIMANTAN SELATAN
Authors: Angriani Farida , Kumalawati Rosalina
Published: February 2020

ABSTRAK

Penelitian ini bertujuan untuk melakukan pemetaan daerah bahaya banjir di Kabupaten Hulu Sungai Tengah Provinsi Kalimantan Selatan. Disain penelitian menggunakan pendekatan survei pada masyarakat di daerah bahaya bencana banjir di Kabupaten Hulu Sungai Tengah Provinsi Kalimantan Selatan.Populasi penelitian adalah masyarakat di daerah bencana banjir. Pemilihan sampel dilakukan dengan metode stratified random sampling. Penelitian ini menggunakan tingkat kerawanan sebagai sampling frame, kemudian sampling frame tersebut dibagi ke dalam empat strata yakni tingkat bahaya tinggi, sedang, rendah dan tidak bahaya. Hasil Penelitian menunjukkan bahwa tingkat bahaya banjir di Kabupaten Hulu Sungai Tengah sebagian besar daerahnya masuk tidak bahaya (957.36 Km2). Bahaya rendah (243,82 Km2), bahaya sedang (455,01 Km2), dan bahaya tinggi (114,91 Km2). Daerah yang tidak bahaya dan bahaya rendah dapat dijadikan sebagai tempat pengungsian apabila terjadi bencana banjir di daerah penelitian. Kata Kunci : Pemetaan, Bahaya banjir.
ANALISA INDEKS KEKERINGAN DENGAN METODE STANDARDIZED PRECIPITATION INDEX (SPI) DAN PRODUKTIVITAS SAWAH TADAH HUJAN DI KABUPATEN INDRAMAYU
Authors: Andono Priyo Atmojo Widi , Andi Warnadi , Setianingsih Asma irma
Published: February 2020

Penelitian ini bertujuan untuk memetakan kekeringan dan menganalisis produktivitas padi sawah tadah hujan di Kabupaten Indramayu Jawa Barat. Penelitian ini menggunakan metode deskriptif. Unit analisis adalah produktivitas padi sawah tadah hujan di Kecamatan Indramayu, Kecamatan Haurgeulis, dan Kecamatan Gantar dengan satuan kw/ha. Data produktivitas padi dianalisis dengan indeks kekeringan yang didapatkan melalui metode SPI di Kabupaten Indramayu Jawa Barat. Kekeringan di Kabupaten Indramayu mengalami kekeringan yang dimulai dari Bulan Mei sampai dengan Bulan Oktober. Daerah yang rawan bencana kekeringan dalam periode 10 tahun terakhir ialah daerah Poligon Anjatan dengan 33 kali kejadian kekeringan. Bulan Agustus mengalami kejadian kekeringan paling banyak di 3 daerah poligon stasiun hujan. Kabupaten Indramayu memiliki pola tanam pada 2 kali tanam padi dan 1 palawijaya dengan jenis yang bervariasi. Musim tanam pertama padi adalah bulan November-Desember-Januari dan musim tanam kedua Mei-Juni-Juli. Pada periode musim tanam pertama menunjukkan produktivitas yang tinggi, sementara musim tanam kedua menunjukkan penurunan. Pola produktivitas dari masa tanam pertama ke masa tanam kedua rata-rata selama 10 tahun menunjukkan penurunan. Hal ini diikuti juga dengan nilai indeks kekeringan yang pada masa tanam pertama November-Desember-Januari antara norma-sangat basah lalu menjadi agak kering-sangat kering pada masa tanam kedua Mei-Juni-Juli. Kenaikan produktivitas hanya terjadi jika fenomena kemarau basah terjadi yaitu pada masa tanam 2006/2007-2007 di Kecamatan Gantar, masa tanam 2007/2008-2008 di Kecamatan Haurgeulis dan Kecamatan Indramayu, masa tanam 2010/2011-2011 di Kecamatan Indramayu, masa tanam 2012/2013-2013 di Kecamatan Haurgeulis.
PEMETAAN LORONG GUA GARUNGGANG UNTUK GEOWISATA DI DESA KARANG TENGAH, KECAMATAN BABAKAN MADANG, KABUPATEN BOGOR, JAWA BARAT
Authors: SARI GRANDIS KUMALA , MUZANI Dr , Suhardjo Drs
Published: February 2020

The purpose of this research is to map passage of Garunggang cave so that can be made a recommendation for geotourism activity. This research used the descriptive method. The population of this research are all survey station in each cave system which amount 93 stastion covering 26 station in first cave system and 67 station in second cave system. This research held on 2 â€“ 4 September 2016.

The research results show that there are two cave system is formed in the Garunggang Cave. Both of them including type of watery cave and the majority is the cave horizontal. First cave system have a distance about 95,12 meters with one entrance thatâ€™s a Entrance 1 and four aven (a hole on the top of passage cave). First cave system divided into four subsystem with classification for subsystem 1 and subsystem 2 including semi â€“ limited access and subsystem 3 and subsystem 4 including limited access. Subsystem 2 is the subsystem with most various ornament but subsystem 3 have not ornament. Second cave system have a distance about 353,65 meters. Second cave system have three entrance and one aven. Entrance 3 use for general tourist and Entrance 2 with Entrance 4 for special tourist. Second cave system divided into seven subsystem with subsystem 1 including limited access and for subsystem 2 until subsystem 7 including semi â€“ limites access. Although subsystem 1 including limited access, but have most various ornament. Followed by subsystem 2, subsystem 5, subsystem 3, and subsystem 7. Subsystem 6 only have one type of ornament and subsystem 4 have not ornament.Based on the above condition, it can be made a recommendation cave tour track for general tourist, special tourist, and educational tourist.

 

Keyword: Maping of cave, cave geotourism, ornament of cave
KAJIAN PENGGUNAAN METODE IP, STORET, dan CCME WQI DALAM MENENTUKAN STATUS KUALITAS AIR
Authors: Romdania Yuda , Herison Ahmad , Susilo Gatot Eko , Novilyansa Elza
Published: February 2020

Pemantauan kualitas air perlu dilakukan pada air sungai, laut, danau, rawa  dan tanah sehingga dapat dimanfaatkan sesuai dengan kegunaannya bagi makhluk hidup. Kajian  ini bertujuan untuk membandingkan beberapa metode perhitungan indeks kualitas air yang paling efektif, sensitif dan obyektif dalam menentukan status kualitas air permukaan. Metode perhitungan Indeks Kualitas Air (IKA) diperlukan untuk menyederhanakan banyaknya nilai dari berbagai jenis parameter menjadi sebuah angka tunggal yang mampu mendeskripsikan kualitas air, sehingga lebih mudah dipahami oleh masyarakat.  Perhitungan IKA dengan menggunakan metode Storet, IP, dan CCME WQI (Canadian Council of Ministers of The Environment) dilaksanakan di beberapa penelitian di berbagai negara.  Kajian ini akan membandingkan hasil literatur dari penelitian IKA di beberapa negara. Metode tersebut akan dibandingkan dengan beberapa indikator. Hasil kajian menunjukkan Metode IP lebih unggul jika memakai data tunggal karena memiliki kelebihan dari segi biaya dan waktu, namun hanya mempresentasikan status mutu air pada saat itu saja, tidak dalam periode tertentu. Metode Storet dan CCME menggunakan data perulangan sepanjang waktu (time series data) sehingga menggambarkan status mutu air dalam periode tertentu. CCME WQI lebih unggul dari Metode Storet dan Metode IP karena memperhitungkan besarnya selisih hasil pengujian yang melebihi baku mutu melalui F3 (Amplitude). Dari kajian di atas disimpulkan, Metode CCME merupakan metode yang paling tepat untuk menganalisis kualitas air baik pada air permukaan maupun air tanah dengan tingkat efektivitas dan sensitivitas yang lebih tinggi dibandingkan dengan metode lainnya serta penggunaan jumlah dan jenis parameter yang fleksibel.
Implementasi Penataan Ruang di Kawasan Dataran Tinggi Dieng Kabupaten Banjarnegara
Authors: Mukaromah Vina Fadhrotul , Handoyo Joni Purwo
Published: February 2020

Dataran Tinggi terletak di 6 wilayah, yaitu Banjarnegara, Wonosobo, Pekalongan, Batang, Temanggung, dan Kendal. Kawasan yang diprioritaskan berada di Kabupaten Banjarnegara. Pemrioritasan ini didasarkan pada potensi kerusakan lingkungan dan pemanfaatan ruang di dalamnya. Penelitian ini bertujuan untuk menganalisis kondisi penggunaan lahan eksisting beserta peruntukan ruang kawasan sesuai RTRW Kabupaten Banjarnegara Tahun 2011-2031. Selain itu, dianalisis juga kesesuaian antara keduanya, berpedoman pada kriteria dalam Permen ATR/BPN Nomor 6 Tahun 2017 beserta faktor-faktor yang menyebabkan. Metode yang digunakan adalah metode kualitatif. Kondisi eksisting diinterpretasi melalui Citra Quickbird dan survey lapangan. Hasil penelitian menunjukan 11 jenis penggunaan lahan eksisting yang teridentifikasi dengan luasan terbesar kebun sayur dan ada 10 jenis peruntukan ruang dengan luasan terbesar lahan pertanian hortikultura. Tingkat kesesuaian keduanya tergolong tinggi. Dari kriteria jenis dan besaran, ketidaksesuaian memiliki persentase sebesar 9,36%. Dari segi dampak, pemanfaatan ruang menimbulkan dampak lokal dan regional. Kondisi ini dipengaruhi oleh faktor alami, faktor sosial, serta faktor lainnya (faktor teknis dan faktor regulasi).

Kata-Kata Kunci : penggunaan lahan, peruntukan ruang, implementasi penataan ruang
Migration Pattern of Industrial Workers in Bekasi Regency
Authors: Sony Nugratama Hijrawadi  , Adrian
Published: February 2020

Bekasi Regency, which is located in the periphery cities of Jakarta and Bekasi, has experienced significant regional development. As an industrial area, Bekasi Regency is very attractive to prospective workers. The population problem that needs attention is the employment issue. As the population increases, the number of workers also increases. The purpose of this study is to geographically identify the area of origin of industrial labor in the Bekasi District which is the most dominant, to find out the characteristics of the industrial sector workforce based on their level of education and competence. This research used a quantitative descriptive method with a survey approach, and also conducted interviews with stakeholders, namely the local government of Bekasi Regency
Investment Analysis of New Port Development Project As a Solution to Overload Problems in Long Ports
Authors: Aditiya Pandi , Herison Ahmad , Kustiani Ika , Siregar Amril Ma’ruf
Published: February 2020

The increasing demand for port services at the Panjang port causes high levels of ship queues. The solution to overcome this problem is to build a new port. However, this new port construction project has not yet conducted a feasibility study. The purpose of this study is to assess the feasibility of port development in the Panjang district of Bandar Lampung in terms of investment or financial aspects. The methods are Benefit-Cost Ratio, Net Present Value, Payback Period, and Internal Rate of Return. The results of the feasibility study of the most profitable investment are in the seventh scenario, the Net Present Value (NPV) of Rp. 463,292,122,605.34, the BCR result of 1.2959, the IRR yield of 12.11% and the Payback Period (PP) occur in the year to thirty-seventh with an economic age of 60 years. The conclusion is that the construction of a new port can be a solution to overcome the overload of Panjang port.
Teacher Shortage and Alternative Licensure Solutions for Technical
Educators

Authors: Devier Britton H.
Published: February 2020

Career and technical education (CTE) continues to face an annual shortage of
qualified teachers in the profession. This shortage has caused an increase in the use of
alternative certification/licensure pathways across all 50 states and the District of
Columbia. These alternative pathways are highly divergent from state to state. Limited
research has investigated the alternative certification/licensure requirements that may
contribute to CTE teacher shortage. This predictive correlational study looked to
determine if CTE alternative certification/licensure requirements could predict CTE
teacher shortages. It was found that CTE alternative certification/licensure
requirements were not a good predictor of CTE teacher shortage.
MEMAHAMI PERTALIAN DESA PAKRAMAN DI BALI DENGAN KARANG AYAHAN SEBAGAI BAGIAN DARI PALEMAHAN BERDASARKAN KONSEP TRI HITA KARANA
Authors: Wiguna Made Oka Cahyadi
Published: February 2020

Desa Pakraman in Bali is included in the category of territorial customary law community and at the same time religious customary law community. On that basis, it should be understood that actually desa pakraman has autonomy in regulating the order of life and social life of its members. The existence of desa pakraman in Bali is very much needed for its members, as an institution that has the authority to regulate the life arrangements of indigenous law communities, including regulating, management, designation, maintenance and preservation of karang ayahan as the customary land of desa pakraman. The existence of karang ayahan is very dependent on the existence of a desa pakraman. Mastery of karang ayahan by krama desa who has the right, is used as a place of residence or other interests with the obligation to pay attention to certain general provisions set by desa pakraman in awig-awig and perarem. Besides that, the karang ayahan is also an integral part of the territory or wewengkon of a desa pakraman. For village people, the area is an important part of sovereignty from a desa pakraman that must be maintained.

 

Keywords: the existence of desa pakraman, the function of the karang ayahan
Penegakan Hukum Pidana Terhadap Penyebaran Berita Bohong Di Sosial Media
Authors: Dwinanda Renza Ardhita
Published: February 2020

Pesatnya Perkembangan Teknologi Informasi mempengaruhi perilaku dan gaya hidup masyarakat. Semakin banyaknya perangkat berbasis Teknologi Informasi dan akses internet berimbas kepada semakin banyaknya pengguna internet. Sebagian besar pengguna internet mengakses internet khususnya mengakses medsos, di sisi lain HOAX, ujaran kebencian, berkembang pesat melalui medsos. Efek HOAX, ujaran kebencian sangat besar di kehidupan sosial masyarakat. Media Sosial online menjadi sarana penyebaran HOAX, begitu banyak masyarakat yang terpengaruh HOAX, sehingga akhirnya dibentuklah Satgas Anti Hoax oleh pemerintah. Namun untuk menanggulangi HOAX pemerintah tidak cukup kuat untuk bekerja sendiri, masyarakat dan berbagai pihak harus ikut serta membantu melawan HOAX. berita bohong (hoax) diatur dalam Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik Pasal 28 ayat (1) dan (2). Penyebaran berita bohong () bisa menjadi perbuatan pidana bila unsur – unsur yang ada dalam Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik Pasal 28 ayat (1) dan (2) terpenuhi. Pertanggungjawaban pelaku penyebaran berita bohong (hoax) ada pada Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik juncto UndangUndang Nomor 19 Tahun 2016 tentang Perubahan atas Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik Pasal 45A ayat (1) dan (2).
Implementasi Pengawasan dan Pengendalian Minuman Beralkohol Melalui Cukai Di Kabupaten Sleman
Authors: Wicaksono Tio Tegar
Published: February 2020

Tujuan dari penelitian ini adalah untuk mengetahui upaya yang dilakukan oleh Kantor Pengawasan dan Pelayanan Bea dan Cukai Yogyakarta dalam mengawasi dan mengendalikan minuman beralkohol melalui cukai di Kabupaten Sleman, juga untuk mengetahui kendala yang ditemui dalam melakukan pengawasan serta solusi untuk mengatasi hambatan tersebut.

Metode penelitian yang digunakan dalam penulisan hukum ini adalah normatif empiris dengan sifat deskriptif. Penelitian ini diawali dengan penelitian kepustakaan untuk memperoleh data sekunder dilanjutkan dengan penelitian lapangan untuk memperoleh data primer. Data yang diperoleh dari hasil penelitian kepustakaan dan lapangan dianalisis secara kualitatif. Hasil analisis data kemudian diuraikan secara deskriptif.

Kesimpulan dari hasil penelitian penulis adalah: PERTAMA, pengawasan dan pengendalian dilakukan melalui pencegahan dan penindakanberupa kegiatan intelijen, operasi pasar dan ketiga bekerjasama dengan instansi lain. KEDUA, hambatan yang terjadi adalah belum maksimalnya peran masyarakat, kurangnya personel yang bertanggungjawab langsung terhadap pengawasan minuaman beralkohol, kurangnya koordinasi antara instansi pemerintah daerah, dan kualitas informan di tingkat penjual yang belum kuat.
PENGEMBANGAN PERANGKAT PEMBELAJARAN AKUNTANSI DENGAN MENGGUNAKAN PENDEKATAN SAINTIFIK
Authors: Widiasmara Nanditia , Hariani Lilik Sri , Afian Affan
Published: February 2020

This research is a research development of accounting learning tools in adjusting journal material to financial statements. The purpose of this study is to produce learning tools that can be used to support learning activities. The steps applied in this study include: (1) Identification of Potential and Problems; (2) Data Collection; (3) Product Design; (4) Design Validation; (5) Design Revision; (6) Product Trial; (7) Product Revision; and (8) Usage Trial. The subjects of this study were class X students at SMK PGRI 6 Malang, totaling 15 students. Data collection techniques in this study used observation, interviews, and questionnaires. The results of the validation of the learning tools that have been carried out by experts obtain feasible and effective criteria to be applied. The implication of this research development in accounting learning tools is that students become more active in learning activities because learning activities are more student-center.
PENGARUH KEMAMPUAN MANAJERIAL KEPALA SEKOLAH, DISIPLIN KERJA, DAN KOMUNIKASI INTERPERSONAL TERHADAP KINERJA GURU
Authors: Gita Nova , Kustiani Lilik , Firdaus Riril Mardiana
Published: February 2020

Objective of the research to reveal the influence of the principal managerial ability, work discipline, and interpersonal communication affects the teacher performance. The study uses a quantitative approach to the type of ex post facto research. The population is 06 teachers of SMK PGRI Malang. A sample of 58 respondents. The technique of collecting data using questionnaires and documentation. Analysis of data using multiple linear regression results show that (1) There is a significant influence managerial skills of principals, work discipline, and interpersonal communication simultaneously on teacher performance, (2) There is a significant influence managerial capability Principal partially on teacher performance (3) No effect on the performance of teachers' work discipline, (4) there is a significant influence interpersonal communication partially on teacher performance.
Augmented Reality untuk Sistem Pernafasan pada Manusia
Authors: Amalia Eka Larasati , Suryani H Dhebys
Published: February 2020

Teknologi maju dengan cepat karena banyak hal yang tidak mungkin beberapa tahun yang lalu menjadi mungkin sekarang. Augmented Reality adalah sintetis, realitas simulasi komputer atau rekreasi dari lingkungan waktu-nyata di mana pengguna dapat berinteraksi dengan lingkungan nyata yang direplikasi

Biologi hanya diajarkan dengan cara konvensional melalui buku sehingga membuat siswa hanya memperhatikan teks dan gambar. Untuk menarik minat mereka, pelajaran akan menjadi lebih menarik dan interaktif jika siswa dapat melihat proses secara langsung dalam bentuk 3D sebagai itu membuat siswa menghafalkannya dengan nyaman. Sistem pernapasan dan sirkulasi darah adalah contoh dari Biologi untuk kelas dua SMP. Dengan menerapkan Augmented Reality, mereka dapat mengambil pelajaran secara interaktif melalui objek digital dalam kenyataan.

Desain Augmented Reality dalam sistem pernapasan dan sirkulasi darah untuk siswa SMP dibuat dengan aplikasi Blender. Pembuatan aplikasi AR dengan platform android menggunakan kesatuan engine game. Berdasarkan uji fungsional yang dilakukan oleh para peneliti, dapat disimpulkan bahwa dengan menerapkan aplikasi tersebut, pengguna dapat memperoleh informasi terkait sistem pernapasan dan sirkulasi darah manusia yang dapat disampaikan secara menarik dan interaktif kepada para siswa
Implementasi Alat Pendeteksi Kadar Air pada Bahan Pangan Berbasis Internet Of Things
Authors: Prasetyo Tri Ferga , Isdiana Abghi Firas , Sujadi Harun
Published: February 2020

Kadar air adalah sejumlah air yang terkandung di dalam suatu benda, seperti tanah, bahan pertanian, dan sebagainya. Penentuan kadar air dari suatu bahan pangan sangat penting agar dalam proses pengolahan maupun pendistribusian mendapat penanganan yang tepat. Karena jika terjadi penanganan yang tidak tepat dalam pengolahan dan penentuan kadar air yang salah maka akan terjadi kerusakan pada pangan yang dapat membahayakan dalam kesehatan. Oleh karena itu pengukuran jumlah kadar air dalam bahan pangan itu penting. Alat pengukur jumlah kadar air berbasis android ini merupakan suatu alat yang memberikan informasi kadar air dalam pangan yang berbasis Internet of Things. Alat ini di kontrol oleh microcontroller Wemos D1 Mini dengan menggunakan sensor soil moisture yang outputnya ditampilkan di LCD dan aplikasi android “Blynk” Menggunakan koneksi. Jumlah kadar air akan ditampilkan dalam LCD dan aplikasi android “Blynk” dengan menghasilkan temperature dalam bentuk celcius dan kelembaban dalam bentuk angka dengan persen dari 0% sampai 100% , sehingga kita dapat melihat seberapa besar tingkat kadar airnya dengan baik.
Identification of KIF23 as a prognostic signature for ovarian cancer based on large scale samples and clinical validation
Authors: Hu Yuexin , Zheng Mingjun , Wang Caixia , Wang Shuang , Gou Rui , Liu Ouxuan , Li Xiao , Liu Juanjuan , Lin Bei
Published: February 2020

Background: Ovarian cancer is one of the common malignant tumors in gynecology. Although the treatment strategy for ovarian cancer has been greatly improved in recent years, due to the metastasis, recurrence and drug resistance, the 5-year overall survival rate of patients is still less than 47%. However, at present, there is no specific markers for clinical application. The purpose of this study is to verify the expression and clinical significance of KIF23 in ovarian cancer and identify potential targets for the clinical treatment of ovarian cancer. Methods: The expression of KIF23 in ovarian cancer tissues and its relationship between survival prognosis and clinical pathological parameters were analyzed in Oncomine, GEO, and TCGA databases. KIF23 expression was analyzed by Kaplan-Meier plotter database and its relationship with chemo-resistance was studied. The molecular mechanism involved in KIF23 was analyzed from the perspective of gene mutation, copy number variation and other genomics. Finally, immunohistochemistry experiment was used to verify the expression of KIF2, and its relationship between the clinical pathological parameters and prognosis of ovarian cancer patients was analyzed by single factor and multivariate Cox regression models. Results: Bioinformatic and experimental results have demonstrated that KIF23 is highly expressed in ovarian cancer, and its high expression is positively correlated with poor prognosis. Overexpression of KIF23 can cause chemotherapy resistance in ovarian cancer and affect the overall survival of patients. Genomics analysis showed that KIF23 expression was associated with mutations such as FLG2 and TTN, and it was significantly enriched in tumor signaling pathways such as DNA replication and cell cycle. Conclusions: KIF23 can not only be used as a biomarker of poor prognosis in patients with various stages of ovarian cancer, but also be used as a molecular targeted drug and an independent prognostic biomarker for the treatment of ovarian cancer patients.
Integrated analysis of long non-coding RNA and mRNA expression in endometrial stromal cells induced by poly (I:C) identifies immune response genes
Authors: Zhang Ming , Zhang Yan , Wu Qiuying , Xu Ling , Zeng Yutian , Lu Chuanzhi , Ren Yan , Wang Zhicheng , Zhou Guangbin , Zeng Changjun , Zuo Zhicai , Song Tianzeng
Published: February 2020

Background The uterus of an animal is relatively easily infected by pathogenic microorganisms, which can cause serious reproductive disorders and economic loss to animal husbandry. The presence of long noncoding RNA (lncRNA) is closely related to many diseases. Poly(I:C) is a synthetic double-stranded RNA that is often used as a substitute for dsRNA viral infection. In this study, we analyzed the mRNA and lncRNA expression profiles of in vitro cultured rabbit endometrial stromal cells (ESCs) after poly(I:C)-induction, to explore the role of these RNAs in the immune response. Results We identified 10,927 lncRNAs and 20,494 mRNAs, of which 291 lncRNAs and 1311 mRNAs were significantly differentially expressed (DE) between the control and poly(I:C) groups ( p <0.05). GO and KEGG analysis showed that DE genes and target genes of DE lncRNAs were enriched in relation to the occurrence of various diseases, development of tissues and organs, metabolic processes, and the immune response. Moreover, these genes were also enriched in many pathways related to immune and inflammatory responses, such as the toll-like receptor and the NF-κB and Jak-STAT signaling pathways. Co-expression analysis of lncRNA and mRNA revealed that there were significant relationships between a number of lncRNAs including MSTRG.153189.1, MSTRG.102664.8, MSTRG.39626.1, MSTRG.68469.1, MSTRG.137189.4, MSTRG.32118.5 and MSTRG.76080.1, and the immune system genes, CCL2, CCL5, IL-1, IL-6, IFN and ISG15, which suggested that lncRNAs in ESCs might be involved in regulation of the immune response to poly(I:C) through genes related to immune signaling pathways. Conclusions Our results provide both transcriptomic and epigenetic insights into the immune response of uterine cells to dsRNA virus infection. Comprehensive lncRNA and mRNA transcriptomes in rabbit ESCs exposed to poly(I:C) were profiled. Co-expression analysis identified an integrated lncRNA-mRNA interaction network, implying that key genes or lncRNAs exerted critical influences on the immune response to virus infection.
Omics-based identification of shared and gender disparity routes in Hras12V-induced hepatocarcinogenesis: an important role for Dlk1-Dio3 genomic imprinting region
Authors: Li Huiling , Zhang Jing , Dong Jianyi , Zheng Xu , Lei Chuanyi , Wang Hong , Zhang Nan , Liu Yang , Luo Xiaoqin , Chen Jun , Wang Jingyu , Wang Aiguo
Published: February 2020

Background: The phenomenon of gender disparity is very profound in hepatocellular carcinoma (HCC). Although previous research has revealed important roles of microRNA (miRNA) in HCC, there are no studies investigating the role of miRNAs in gender disparity observed hepatocarcinogenesis. Results: In the present study, we investigated the global miRNAomics changes related to Ras -induced male-prevalent hepatocarcinogenesis in a Hras12V -transgenic mouse model ( Ras -Tg) by next-generation sequencing (NGS). We identified shared by also unique changes in miRNA expression profiles in gender-dependent hepatocarcinogenesis. 264 differentially expressed miRNAs ( DEMIRs) with q value ≤ 0.05 and fold change ≥ 2 were identified. A vertical comparison revealed that the lower numbers of DEMIRs in the hepatic tumor (T) compared with the peri-tumor precancerous tissue (P) of Ras -Tg and normal liver tissue of wild-type C57BL/6J mice (W) in males indicated that males are more susceptible to develop HCC. The expression pattern analysis revealed 43 common HCC-related miRNAs and 4 Ras -positive-related miRNAs between males and females. By integrating the mRNA transcriptomic data and using 3-node FFL analysis, a group of significant components commonly contributing to HCC between sexes were filtered out. A horizontal comparison showed that the majority of DEMIRs are located in the Dlk1-Dio3 genomic imprinting region (GIR) and that they are closely related to not only hepatic tumorigenesis but also to gender disparity in hepatocarcinogenesis. This is achieved by regulating multiple metabolic pathways, including retinol, bile acid, and steroid hormones. Conclusions: In conclusion, the identification of shared and gender-dependent DEMIRs in hepatocarcinogenesis provides valuable insights into the mechanisms that contribute to male-biased Ras -induced hepatic carcinogenesis.
Large-scale integrated evaluation of salt tolerance in japonica rice at the germination stage
Authors: Jing Xiu , Mi Ping , Xie Xianzhi , Wang Baoshan
Published: February 2020

Background: Salt stress, one of the most important abiotic stresses, severely reduces crop yields. Identifying salt-tolerant rice germplasm resources at the germination stage, developing salt tolerance indicators, and cultivating salt-tolerant rice cultivars are crucial for improving rice production in saline soil.Results: We measured the germination parameters of 140 japonica rice cultivars on the 7 day after sowing (DAS) in 0 and 150 mmol L−1 NaCl. To accurately assess salt tolerance and identify reliable indicators of salt tolerance, we measured the shoot length (SL), root length (RL), root fresh weight (RFW), shoot fresh weight (SFW), total fresh weight (TFW) and salt tolerance (STI) index after 7 days of salt-stress treatment. The 140 rice cultivars were divided into four categories based on the mean MFVs: highly salt tolerant (HST: 19 cultivars), salt tolerant (ST: 74 cultivars), weakly salt tolerant (WST: 43 cultivars), and salt sensitive (SS: 4 cultivars). Based on the physiological indicators, we established a mathematical model to accurately evaluate salt tolerance in japonica rice cultivars. STI of TFW under 150 mmol L−1 NaCl treatment showed the highest correlation with salt tolerance during the germination stage.Conclusions: We determined the optimum NaCl concentration (150 mmol L−1) for evaluating salt tolerance in japonica rice at the germination stage. We identified 19 HST, 74 ST, 43 WST, and 4 SS japonica rice cultivars during the germination stage and proposed a mathematical model to evaluate salt tolerance. STI of TFW is a reliable, accurate indicator for evaluating salt tolerance in japonica rice. These findings should greatly facilitate the evaluation of japonica rice cultivars during seed germination and the breeding of salt-tolerant rice cultivars.
Three-dimensional versus two-dimensional derived strain echocardiography for assessing right ventricular myocardial deformation in patients with chronic left ventricular heart failure: A proof-of-concept study
Authors: Gao Fei , Liu Chong , Guo Qiang , Jiang Shuang-quan , Wang Zhen-zhen , Liu Li , Li Hai-Ru , Du Guo-Qing , Tian Jia-wei
Published: February 2020

Background A novel three-dimensional echocardiography (3DE)-derived strain analysis software specialized for right ventricular (RV) monitoring is emerging that could definitely evaluate RV free wall and interventricular septum longitudinal strain. The aim of this study was to compare the diagnostic performance in evaluating RV function between 3DE and two-dimensional echocardiography (2DE)-derived longitudinal strain. Methods Echocardiographic examinations were performed in 82 patients with RV dysfunction associated with chronic left-sided heart failure and 40 control subjects. RV dysfunction was defined as a 3DE-derived RV ejection fraction (EF) <45%. Both 2DE and 3DE-derived strain analyses were performed in all the patients to measure the longitudinal strain of RV. Results 3DE-derived peak systolic longitudinal strain of RV free wall (RV-fwLS) was significantly lower in patients with RV dysfunction compared to control subjects (-14.0±4.1 vs. -26.7±4.7%; p<0.001), and it correlated well with cardiac magnetic resonance-derived RVEF (r=0.74, p<0.001). On receiver operator characteristic analysis, a 3DE-derived RV-fwLS cutoff value of >-21.1% was most useful in identifying patients at higher risk of RV dysfunction (sensitivity: 90% and specificity: 85%), also higher than 2DE-derived strain parameters. Additionally, RV dysfunctional patients with pulmonary hypertension (PH) had significantly reduced 3DE-derived RV-fwLS value than the subgroup without PH (-13.1±3.8 vs. -15.0±4.2; p<0.05). Conclusion Assessment of RV myocardial function by 3DE-derived longitudinal strain is better than 2DE in identifying patients with impaired RV systolic function. 3DE-derived strain analysis for RV should be considered as a complementary tool for assessing RV systolic function in terms of accuracy.
A rare case of maxillary ameloblastoma with lung metastasis: a case report
Authors: Sohal Karpal Singh , Mlaga Salvatory M , Vuhahula Edda A
Published: February 2020

Background

Ameloblastomas are low-grade neoplasms of odontogenic epithelium that account for about 1% of all oral tumours and about 10% of odontogenic tumours. Rarely, these tumours have a potential of distance metastasis, and once they do metastasize, they are termed as metastatic ameloblastoma.

Case presentation

A 24-year-old African man presented with a massive swelling on the right side of the face for 2 years in 2018. He was previously operated for a swelling in the right side of the maxilla in 2012, which was histologically diagnosed as ameloblastoma. Clinical and radiological evaluation revealed a massive maxillary tumour that had a local extension to the brain. X-ray and CT scan of chest pointed out to metastatic mass in the lungs. Histology of the recurrent tumour mass revealed it to be follicular ameloblastoma and CT-guided fine-needle aspiration cytology of the lung mass showed microscopic features of ameloblastoma similar to primary jaw tumour.

Conclusion

A Close and long-term follow-up is mandatory in patients diagnosed with ameloblastoma even years after primary resection.
WITHDRAWN: Pharmacist-led interventions might improve quality of life among older adult patients receiving warfarin treatment in rural areas: results from a randomized controlled trial
Authors: Falamić Slaven , Hadziabdic Maja Ortner , Lucijanić Marko , Marušić Srećko , Vrca Vesna Bačić
Published: February 2020

Background: Available literature supports the role of a pharmacist in the management of patients on warfarin therapy. However, randomized controlled trials on the influence of pharmacists’ interventions on the quality of life (QoL) in elderly patients on warfarin are missing. The aim of this study was to investigate the effect of pharmacists’ interventions on QoL of older adult patients receiving warfarin therapy in rural areas. The study aimed also to explore factors influencing QoL in these patients. Methods: We conducted a prospective randomized trial in a community pharmacy setting in a rural area. Eligible patients were randomized into intervention and control groups. Repeated education and a follow up plan were provided to the participants in the intervention group, and, if needed, pharmacist intervened to optimize warfarin therapy in collaboration with GP. QoL was measured using the DASS (Duke Anticoagulation Satisfaction Scale) questionnaire in both groups after 6 months. Results: In total, 131 participants finished the study (median age 73 years; 51.1% men). Participants in the intervention group scored significantly lower in all 3 domains of the DASS questionnaire at 6 months, namely limitations, hassles and burden, and psychological impact, as well as in overall scores (median score 86.5 and 66.0 in control and intervention group, respectively; p<0.001), indicating higher QoL in the intervention group. Adverse drug reactions (ADRs) and pharmacist’s intervention were predictive of QoL (r 2 =65.5%, P<0.001). Experience of ADRs was the strongest negative predictor of QoL (P<0.001). Conclusions: The study demonstrated that pharmacist’s intervention had positive impact on the QoL among older adult patients in rural areas. ADRs and pharmacist’s intervention were identified as predictive factors for QoL, whereby experience of ADRs was the strongest negative predictor. These results suggest that older adult patients receiving warfarin in rural areas could benefit from a community pharmacist intervention.