bluuebunny/crossref_metadata_2025 huggingface dataset:
Strontium and 87Sr/86Sr isotopic ratio of ground brines in the northeastern Angara-Lena artesian basin
Authors: Alekseeva L. P. , Alekseev S. V.
Published: June 2021

The purpose of this study is to identify the major formation processes of the ionic and isotopic composition of chloride brines in the sedimentary basins of the Siberian platform. The object and subject of research are deep-seated strong, very strong and extremely saturated brines as well as their strontium content and the ratio of Sr stable isotopes. The groundwater ionic-salt composition was determined by traditional methods (titrimetric, gravimetric, flame photometry), the 87Sr/86Sr isotopic ratio was measured using mass-spectrometers (Irkutsk, Russia and Canada). The brines lying at the depth of 1500–3000 m were tapped and classified into saline and subsalt hydrogeological formations. Their feature is high salinity (385–530 g/L) and high content of strontium (2.3–7 g/L). The 87Sr/86Sr isotopic ratio ranges from 0.708 to 0.713062. By isotopic composition most of the brine samples are close to the waters of the Vendian-Cambrian paleoocean. However, some brine samples from the subsalt part of the sedimentary section of the basin are significantly enriched in the isotope 87Sr compared to the paleoocean waters and other samples. It could be due to the substantial input of 87Sr into the brines during the long-term interaction of groundwater with the host Lower Cambrian sandstones.
Performance modelling of direct contact membrane distillation using a hydrophobic/hydrophilic dual-layer membrane
Authors: Boztepe Inci , Gray Stephen , Zhang Jianhua , Li Jun-De
Published: June 2021

HFP-co-PVDF/N6 hydrophobic/hydrophilic dual-layer membrane was used to study desalination with direct contact membrane distillation (DCMD). A one-dimensional (1-D) model was proposed to predict the flux and thermal efficiency. Heat and mass transfer equations were solved numerically for the combined hydrophilic and hydrophobic layers. The membrane characteristics of the hydrophobic layer were considered for the calculation of the mass transfer coefficients, while the hydrophilic layer was ignored since it was assumed to be filled with water. However, the hydrophilic layer was taken into account during the calculations of conductive heat transfer. Therefore, the equations are different, compared to single-layer hydrophobic membranes. It was found that with the same hydrophobic membrane characteristics, the single-layer membranes performed with better flux and thermal efficiency than the dual-layer membranes. Furthermore, the improvement of flux and thermal efficiency by an addition of the hydrophilic layer has not been observed experimentally, and it is suggested that the improved performance for dual-layer membranes reported previously is due to improved permeability by using thinner and more porous hydrophobic layers that can be mechanically reinforced by the hydrophilic layer. The validation of the model was conducted by comparing the experimental results for single- and dual-layer membranes with the modelling results. The predicted flux and thermal efficiency by the modelling were within 10% error to the experimental results.
Anaerobic digestion of dried/shredded food waste in a periodic anaerobic baffled reactor
Authors: Mathioudakis D. , Michalopoulos I. , Kalogeropoulos K. , Papadopoulou K. , Lyberatos G.
Published: June 2021

The objective of the current work is to study the impact of the operational parameters' variation (HRT, OLR and T) on biomethane productivity in a periodic anaerobic baffled reactor (PABR). The feedstock used was a biomass product named food residue biomass (FORBI), which is dried and shredded source-separated household food waste. The PABR is an innovative, high-rate bioreactor. Apart from the hydraulic retention time (HRT) and the organic loading rate (OLR), an important operational parameter is the switching period (T) of the feeding compartment: when T is high, the bioreactor operation is similar to an anaerobic baffled reactor (ABR), while when it is low, the operation approaches that of an upflow anaerobic sludge blanket reactor (UASBR). Nine distinct experimental phases were conducted, during which the operational parameters of the PABR were consecutively modified: the HRT varied from 9 to 2.5 days, T between 2 days and 1 and finally the OLR from 1.24 gCOD/Lbioreactor*d to 8.08 gCOD/Lbioreactor*d. The maximum biomethane yield was 384 LCH4/kgFORBI corresponding to the operation at HRT = 5 d, OLR = 2.14 gCOD/Lbioreactor*d and T = 2 days. Similar efficiency (333 LCH4/kg­FORBI) was achieved at higher OLR (4.53 gCOD/Lbioreactor*d).
Production of Lysinibacillus sphaericus Mosquitocidal Protein Mtx2 from Bacillus subtilis as a Secretory Protein
Authors: Trakulnaleamsai Chutchanun , Promdonkoy Boonhiang , Soonsanga Sumarin
Published: June 2021

Background:

Mtx2 is a mosquitocidal toxin produced during the vegetative growth of
Lysinibacillus sphaericus. The protein shows synergism with other toxins against mosquito larvae;
hence it could be used in mosquito control formulations. The protein expression system is needed
for Mtx2 development as a biocontrol agent.

Objective:

This study aimed to set up a Bacillus subtilis system to produce Mtx2 as a secreted protein
since the protein contains a putative signal peptide.

Methods:

Initially, four different promoters (P43, Pspac, PxylA, and PyxiE) were compared for
their strength using GFP as a reporter in B. subtilis. Subsequently, six different signal peptides
(SacB, Epr, AmyE, AprE, LipA, and Vip3A) were tested in conjunction with the selected promoter
and mtx2 to evaluate levels of Mtx2 secreted by B. subtilis WB800, an extracellular protease-deficient
strain.

Results:

The promoter PyxiE showed the highest GFP intensity and was selected for further study.
Mtx2 was successfully produced as a secreted protein from signal peptides LipA and AmyE, and it
exhibited larvicidal activity against Aedes aegypti.

Conclusion:

B. subtilis was successfully developed as a host for the production of secreted Mtx2,
and the protein retained its larvicidal activity. Although the Mtx2 production level still needs improvement,
the constructed plasmids could be used to produce other soluble proteins.
Early Prediction of Malignant Mesothelioma: An Approach Towards Non-invasive Method
Authors: Shabbir Shakir , Asif Muhammad Shahzad , Alam Talha Mahboob , Ramzan Zeeshan
Published: June 2021

Background:

Malignant Mesothelioma (MM) is a rare but aggressive tumor that arises in the
lungs. Commonly, costly imaging and laboratory resources, i.e. (X-rays imaging, Magnetic Resonance
Imaging (MRI), Positron Emission Tomography (PET) scans, biopsies, and blood tests) have already
been utilized for the diagnosis of MM. Even though these diagnostic measures are expensive and unavailable
in distant areas, some of these diagnosis methods are also very painful for the patient, i.e., biopsy
and cytology of pleural fluid.

Objective:

In this study, we proposed a diagnosis model for early identification of MM via machine
learning techniques. We explored the health records of 324 Turkish patients, which show the symptoms
related to MM. The data of patients include socio-economic, geographical, and clinical features.

Methods:

Different feature selection methods have been employed for the selection of significant features.
To overcome the data imbalance problem, various data-level resampling techniques have been
utilized to obtain efficient results. The Gradient Boosted Decision Tree (GBDT) method has been used
to develop the diagnostic model. The performance of the GBDT model is also compared with traditional
machine learning algorithms.

Results :

Our model's results outperformed other models, both on balance and imbalance data. The results
clearly show that undersampling techniques outperformed by imbalanced data even without
resampling based on accuracy and Receiving Operating Characteristic (ROC) value. Conversely, it has
also been observed that oversampling techniques outperformed undersampling and imbalanced data
based on accuracy and ROC. All classifiers employed in this study achieved efficient results utilizing
feature selection-based methods (OneR, information gain, and Relief-F), but the results of the other two
methods (gain ratio and Correlation) were not entirely promising. Finally, when the combination of
Synthetic Minority Oversampling Technique (SMOTE) and OneR was applied with GBDT, it gave the
most favorable results based on accuracy, F-measure, and ROC.

Conclusion:

The diagnosis model has also been deployed to assist doctors, patients, medical practitioners,
and other healthcare professionals for early diagnosis and better treatment of MM.
Novel G6PC3 Mutations in Patients with Congenital Neutropenia: Case Reports and Review of the Literature
Authors: Maroufi Seyed F. , Shaka Zoha , Mojtabavi Helia , Sadeghalvad Mona , Rayzan Elham , Sedighi Iraj , Shahkarami Sepideh , Najafi Mehri , Rohlfs Meino , Klein Christoph , Rezaei Nima
Published: June 2021

Background:

Severe congenital neutropenia (SCN4) caused by mutations in glucose-6-
phosphatase catalytic subunit 3 (G6PC3) is characterized by recurrent infections due to severe neutropenia,
may be accompanied by other extra-hematopoietic manifestations; including structural heart
defects, urogenital abnormalities, prominent superficial venous markings, growth retention, and inflammatory
bowel diseases with rare incidence. The homozygous or compound heterozygous mutations
of G6PC3 are responsible for most cases of autosomal recessive SCN4. Herein, we present two
cases of SCN4 affected by novel mutations in the G6PC3, in addition to a summarized list of variants
in G6PC3 gene that are reported as pathogenic and related to the SCN4 phenotype.

Case presentation:

Herein, we present two cases of SCN4; the first case was a three-months old boy
with severe neutropenia and prior history of hospitalization due to umbilical separation, umbilical herniation,
omphalitis, and pyelonephritis; and the second case was an eight-year-old with a history of
neutropenia, recurrent and severe episodes of intractable diarrhea, refractory rectovaginal and rectoperineal
fistula, congenital inguinal hernia, and ASD type 2. Whole exome sequencing was performed for
both cases, which revealed two novel homozygous missense mutations in G6PC3 that were predicted
to be deleterious; c.337G>A, p. Gly113Arg in the first case and c.479C>T; P. Ser160Leu in the second
case. To our knowledge, both of these two mutations have not been reported in the G6PDC3 gene.

Conclusions:

In patients with severe neutropenia with varying extra hematopoietic syndrome, mutation
of G6PC3 should be suspected after ruling out other mutations related to neutropenia. This study
pointed toward novel G6PC3 mutations that should be considered in order to diagnose patients with
severe congenital neutropenia.
Taming the Storm in the Heart: Exploring Different Therapeutic Choices Against Myocardial Inflammation in COVID-19
Authors: Choudhury Abhigyan , Mukherjee Suprabhat
Published: June 2021

Mechanism of cardiac injury in COVID-19 is a serious problem and
plays critical role in mediating the severity of the disease. However, the mechanistic
insights of the induction of the inflammatory signal leading to cardiac injury
was poorly understood. However, few recent studies have indicated the involvement
of Toll-Like Receptors (TLRs) as the major ‘culprit’ behind eliciting
the initial signal of ‘cytokine storm’. As a result, TLRs are now considered as the
therapeutic targets to develop efficacious therapeutics. Herein, we present an
overall summary on the mechanistic insight of cardiac injury in COVID-19 patients
and the therapeutic promises of TLR-targeted therapies.
Internet-Administered Cognitive Behavioral Therapy for Common Mental Health Difficulties in Parents of Children Treated for Cancer: Intervention Development and Description Study
Authors: Woodford Joanne , Farrand Paul , Hagström Josefin , Hedenmalm Li , von Essen Louise
Published: June 2021

Background

Following the end of a child’s treatment for cancer, parents may report psychological distress. However, there is a lack of evidence-based interventions that are tailored to the population, and psychological support needs are commonly unmet. An internet-administered low-intensity cognitive behavioral therapy (LICBT)–based intervention (EJDeR [internetbaserad självhjälp för föräldrar till barn som avslutat en behandling mot cancer]) may provide a solution.

Objective

The first objective is to provide an overview of a multimethod approach that was used to inform the development of the EJDeR intervention. The second objective is to provide a detailed description of the EJDeR intervention in accordance with the Template for Intervention Description and Replication (TIDieR) checklist.

Methods

EJDeR was developed through a multimethod approach, which included the use of existing evidence, the conceptualization of distress, participatory action research, a cross-sectional survey, and professional and public involvement. Depending on the main presenting difficulty identified during assessment, LICBT behavioral activation or worry management treatment protocols are adopted for the treatment of depression or generalized anxiety disorder when experienced individually or when comorbid. EJDeR is delivered via the Uppsala University Psychosocial Care Programme (U-CARE) portal, a web-based platform that is designed to deliver internet-administered LICBT interventions and includes secure videoconferencing. To guide parents in the use of EJDeR, weekly written messages via the portal are provided by e-therapists comprising final year psychology program students with training in cognitive behavioral therapy.

Results

An overview of the development process and a description of EJDeR, which was informed by the TIDieR checklist, are presented. Adaptations that were made in response to public involvement are highlighted.

Conclusions

EJDeR represents a novel, guided, internet-administered LICBT intervention for supporting parents of children treated for cancer. Adopting the TIDieR checklist offers the potential to enhance fidelity to the intervention protocol and facilitate later implementation. The intervention is currently being tested in a feasibility study (the ENGAGE study).

International Registered Report Identifier (IRRID)

RR2-10.1136/bmjopen-2018-023708
Prevalence of Early Childhood Caries in South Africa: Protocol for a Systematic Review
Authors: Kimmie-Dhansay Faheema , Barrie Robert , Naidoo Sudeshni , Roberts Tina Sharon
Published: June 2021

Background

Young children are at the highest risk of developing dental caries as they have a lack of autonomy over their diet and oral hygiene practices. Dental caries develops over time due to demineralization of tooth substance (enamel), which results from acid production during sugar metabolism by bacteria. Early onset of dental caries often results in asymptomatic presentation, but if left untreated, it can result in severe pain, infection, and dentoalveolar abscesses. Early childhood caries (ECC) is defined as dental caries in children aged 6 years and younger and is a significant public health problem in South Africa. According to the Global Burden of Disease study, untreated dental caries of primary teeth affects 532 million children. Untreated dental caries has many detrimental effects which can affect the physical development and reduce the quality of life of affected children. Furthermore, long-term untreated dental caries can result in school absenteeism, low BMI, and poor educational outcomes.

Objective

The purpose of this study was to determine the prevalence and severity of ECC in South Africa in children under the age of 6 years.

Methods

All cross-sectional studies documenting the prevalence and severity of dental disease (decayed, missing, and filled teeth scores) will be included. Various databases will be searched for eligible studies. Only studies conducted on South African children aged 6 years and under will be included. There will be no restriction on the time or language of publication. The quality of all eligible studies will be analyzed by a risk of bias tool developed by the Joanna Briggs Institute. The results will be presented narratively, and if possible, a meta-analysis will be conducted.

Results

The protocol is registered with PROSPERO. The literature search was initially conducted in November 2018 and was repeated in November 2020.

Conclusions

The results of this study will be used to advise stakeholders of the prevalence and severity of dental disease in children under 6 years of age in South Africa.

Trial Registration

PROSPERO CRD42018112161;

International Registered Report Identifier (IRRID)

DERR1-10.2196/25795
Methods for Authenticating Participants in Fully Web-Based Mobile App Trials from the iReach Project: Cross-sectional Study
Authors: Guest Jodie L , Adam Elizabeth , Lucas Iaah L , Chandler Cristian J , Filipowicz Rebecca , Luisi Nicole , Gravens Laura , Leung Kingsley , Chavanduka Tanaka , Bonar Erin E , Bauermeister Jose A , Stephenson Rob , Sullivan Patrick S
Published: June 2021

Background

Mobile health apps are important interventions that increase the scale and reach of prevention services, including HIV testing and prevention counseling, pre-exposure prophylaxis, condom distribution, and education, of which all are required to decrease HIV incidence rates. The use of these web-based apps as well as fully web-based intervention trials can be challenged by the need to remove fraudulent or duplicate entries and authenticate unique trial participants before randomization to protect the integrity of the sample and trial results. It is critical to ensure that the data collected through this modality are valid and reliable.

Objective

The aim of this study is to discuss the electronic and manual authentication strategies for the iReach randomized controlled trial that were used to monitor and prevent fraudulent enrollment.

Methods

iReach is a randomized controlled trial that focused on same-sex attracted, cisgender males (people assigned male at birth who identify as men) aged 13-18 years in the United States and on enrolling people of color and those in rural communities. The data were evaluated by identifying possible duplications in enrollment, identifying potentially fraudulent or ineligible participants through inconsistencies in the data collected at screening and survey data, and reviewing baseline completion times to avoid enrolling bots and those who did not complete the baseline questionnaire. Electronic systems flagged questionable enrollment. Additional manual reviews included the verification of age, IP addresses, email addresses, social media accounts, and completion times for surveys.

Results

The electronic and manual strategies, including the integration of social media profiles, resulted in the identification and prevention of 624 cases of potential fraudulent, duplicative, or ineligible enrollment. A total of 79% (493/624) of the potentially fraudulent or ineligible cases were identified through electronic strategies, thereby reducing the burden of manual authentication for most cases. A case study with a scenario, resolution, and authentication strategy response was included.

Conclusions

As web-based trials are becoming more common, methods for handling suspicious enrollments that compromise data quality have become increasingly important for inclusion in protocols.

International Registered Report Identifier (IRRID)

RR2-10.2196/10174
Development, Acceptance, and Concerns Surrounding App-Based Services to Overcome the COVID-19 Outbreak in South Korea: Web-Based Survey Study
Authors: Park Jihwan , Han Jinhyun , Kim Yerin , Rho Mi Jung
Published: June 2021

Background

Since the COVID-19 outbreak, South Korea has been engaged in various efforts to overcome the pandemic. One of them is to provide app-based COVID-19–related services to the public. As the pandemic continues, a need for various apps has emerged, including COVID-19 apps that can support activities aimed at overcoming the COVID-19 pandemic.

Objective

We aimed to determine which apps were considered the most necessary according to users and evaluate the current status of the development of COVID-19–related apps in South Korea. We also aimed to determine users’ acceptance and concerns related to using apps to support activities to combat COVID-19.

Methods

We collected data from 1148 users from a web-based survey conducted between November 11 and December 6, 2020. Basic statistical analysis, multiple response analysis, and the Wilcoxon rank sum test were performed using R software. We then manually classified the current status of the development of COVID-19–related apps.

Results

In total, 68.4% (785/1148) of the respondents showed high willingness to protect themselves from COVID-19 by using related apps. Users considered the epidemiological investigation app to be the most necessary app (709/1148, 61.8%) overall, followed by the self-management app for self-isolation (613/1148, 53.4%), self-route management app (605/1148, 52.7%), COVID-19 symptom management app (483/1148, 42.1%), COVID-19–related information provision app (339/1148, 29.5%), and mental health management app (270/1148, 23.5%). Despite the high intention to use these apps, users were also concerned about privacy issues and media exposure. Those who had an underlying disease and had experience using COVID-19–related apps showed significantly higher intentions to use those apps (P=.05 and P=.01, respectively).

Conclusions

Targeting users is very important in order to design and develop the most necessary apps. Furthermore, to gain the public’s trust and make the apps available to as many people as possible, it is vital to develop diverse apps in which privacy protection is maximized.
Exploring the Utility of Google Mobility Data During the COVID-19 Pandemic in India: Digital Epidemiological Analysis
Authors: Kishore Kamal , Jaswal Vidushi , Verma Madhur , Koushal Vipin
Published: June 2021

Background

Association between human mobility and disease transmission has been established for COVID-19, but quantifying the levels of mobility over large geographical areas is difficult. Google has released Community Mobility Reports (CMRs) containing data about the movement of people, collated from mobile devices.

Objective

The aim of this study is to explore the use of CMRs to assess the role of mobility in spreading COVID-19 infection in India.

Methods

In this ecological study, we analyzed CMRs to determine human mobility between March and October 2020. The data were compared for the phases before the lockdown (between March 14 and 25, 2020), during lockdown (March 25-June 7, 2020), and after the lockdown (June 8-October 15, 2020) with the reference periods (ie, January 3-February 6, 2020). Another data set depicting the burden of COVID-19 as per various disease severity indicators was derived from a crowdsourced API. The relationship between the two data sets was investigated using the Kendall tau correlation to depict the correlation between mobility and disease severity.

Results

At the national level, mobility decreased from –38% to –77% for all areas but residential (which showed an increase of 24.6%) during the lockdown compared to the reference period. At the beginning of the unlock phase, the state of Sikkim (minimum cases: 7) with a –60% reduction in mobility depicted more mobility compared to –82% in Maharashtra (maximum cases: 1.59 million). Residential mobility was negatively correlated (–0.05 to –0.91) with all other measures of mobility. The magnitude of the correlations for intramobility indicators was comparatively low for the lockdown phase (correlation ≥0.5 for 12 indicators) compared to the other phases (correlation ≥0.5 for 45 and 18 indicators in the prelockdown and unlock phases, respectively). A high correlation coefficient between epidemiological and mobility indicators was observed for the lockdown and unlock phases compared to the prelockdown phase.

Conclusions

Mobile-based open-source mobility data can be used to assess the effectiveness of social distancing in mitigating disease spread. CMR data depicted an association between mobility and disease severity, and we suggest using this technique to supplement future COVID-19 surveillance.
Repeated Transcranial Magnetic Stimulation for Improving Cognition in Alzheimer Disease: Protocol for an Interim Analysis of a Randomized Controlled Trial
Authors: Moussavi Zahra , Koski Lisa , Fitzgerald Paul B , Millikin Colleen , Lithgow Brian , Jafari-Jozani Mohammad , Wang Xikui
Published: June 2021

Background

Many clinical trials investigating treatment efficacy require an interim analysis. Recently we have been running a large, multisite, randomized, placebo-controlled, double-blind clinical trial investigating the effect of repetitive transcranial magnetic stimulation (rTMS) treatment for improving or stabilizing the cognition of patients diagnosed with Alzheimer disease.

Objective

The objectives of this paper are to report on recruitment, adherence, and adverse events (AEs) to date, and to describe in detail the protocol for interim analysis of the clinical trial data. The protocol will investigate whether the trial is likely to reach its objectives if continued to the planned maximum sample size.

Methods

The specific requirements of the analytic protocol are to (1) ensure the double-blind nature of the data while doing the analysis, (2) estimate the predictive probabilities of success (PPoSs), (3) estimate the numbers needed to treat, (4) re-estimate the initial required sample size. The initial estimate of sample size was 208. The interim analysis will be based on 150 patients who will be enrolled in the study and finish at least 8 weeks of the study. Our protocol for interim analysis, at the very first stage, is to determine the response rate for each participant to the treatment (either sham or active), while ensuring the double-blind nature of the data. The blinded data will be analyzed by a statistician to investigate the treatment efficacy. We will use Bayesian PPoS to predict the success rate and determine whether the study should continue.

Results

The enrollment has been slowed significantly due to the COVID-19 pandemic and lockdown. Nevertheless, so far 133 participants have been enrolled, while 22 of these have been withdrawn or dropped out for various reasons. In general, rTMS has been found tolerable with no serious AE. Only 2 patients dropped out of the study due to their intolerability to rTMS pulses.

Conclusions

Overall, the study with the same protocol is going as expected with no serious AE or any major protocol deviation.

Trial Registration

ClinicalTrials.gov NCT02908815; https://clinicaltrials.gov/ct2/show/NCT02908815

International Registered Report Identifier (IRRID)

DERR1-10.2196/31183
Applicability and effectiveness of mobile health services for older adults population with diabetes: A Systematic Review and Meta-Analysis (Preprint)
Authors: Chen Yunying , Wang Xiyi , Fan Guanhua
Published: June 2021

BACKGROUND

Mobile health services educate patients with diabetes regarding their personal condition, helping them better manage the disease and mitigate complications from diabetes.

OBJECTIVE

Because mobile health services use mobile computing devices, such as smartphones, it remains unclear whether such services can meet the needs of older adult patients with diabetes with respect to health information and communication with medical groups. Thus, this study explored how effective and applicable mobile medical services are among older adult patients with diabetes.

METHODS

Adopting a systematic review approach, we searched for peer-reviewed journal articles published between 2010 and 2020. We obtained 523 potentially relevant studies but meta-analyzed the study data of nine of them after applying inclusion and exclusion criteria. Our patients were from three countries and had a mean age of 60 years.

RESULTS

The combined effects were statistically significant; they were 3-month post-intervention weighted mean difference (WMD) = −0.62 (95% CI: −1.06, −0.17) and 6-month post-intervention WMD = −0.42 (95% CI: −0.61, −0.23）.

CONCLUSIONS

Mobile health services are partially effective among older adult patients with diabetes. These services can improve blood sugar levels, depression symptoms, and health conditions. Obstacles remain, such as technical anxiety, but they can be eliminated by including technical guidance and remote supervision services.
ПРИЧИНЫ СИСТЕМНЫХ ПРОБЛЕМ В РАЗВИТИИ РАДИОЭЛЕКТРОННОЙ И ЭЛЕКТРОННОЙ ПРОМЫШЛЕННОСТИ РОССИИ Часть 2. ПЕРИОД 1945–1960 ГОДЫ
Authors: Брыкин А.
Published: June 2021

Развитие производственно-технологического комплекса электронной и радиоэлектронной отрасли связано с приоритетами в развитии промышленности и страны в целом. Анализируется ситуация, которая сегодня сложилась в отрасли, делается попытка ответить на вопрос: возможно ли переломить ситуацию, сложившуюся из-за череды стратегических просчетов прошлых периодов развития страны.
КАК ДОСТИЧЬ ВЫСОКОГО КАЧЕСТВА ПРИ СБОРКЕ, ВЛАГОЗАЩИТЕ, А ТАКЖЕ ПРИ УДАЛЕНИИ ПОКРЫТИЙ ВИЗИТ НА СБОРОЧНОЕ ПРОИЗВОДСТВО ООО НПП «ПРИМА»
Authors: Ковалевский Ю.
Published: June 2021

Нижегородская компания НПП «Прима» в прошлом году отметила 30-летний юбилей. Данное предприятие специализируется на разработке и производстве оборудования, к которому предъявляются повышенные требования в отношении качества и надежности, такого как, например, системы радиосвязи и навигации авиационного и морского применения.

Сборочное производство компании отражает ее специфику. Оно ориентировано на изготовление как опытных образцов, так и небольших партий серийных изделий. В рамках процесса организован тщательный контроль качества, включающий 100%-ную автоматическую оптическую инспекцию (АОИ) поверхностного монтажа и рентгеновский контроль скрытых паяных соединений, а также пайки компонентов, монтируемых в отверстия.

Недавно на производстве появилась новая установка – ​«Борей» от компании «Остек-­Интегра». Это оборудование предназначено для удаления с электронных сборок влагозащитного покрытия микроабразивным методом.

В начале нашего визита в компанию Максим Николаевич Клементьев, начальник производства ООО НПП «Прима», рассказал нам, в частности, какими преимуществами обладает этот метод и почему предприятие выбрало отечественное решение для данной операции.
ЭЛЕКТРОХИМИЧЕСКАЯ СИСТЕМА НАКОПЛЕНИЯ ЭНЕРГИИ НА ОСНОВЕ МНОГОСЛОЙНОГО УГЛЕРОДНО-ПОЛИМЕРНОГО ИОНИСТОРА
Authors: Рябцева А. , Петрова В. , Бельских Г. , Булатников Д. , Тетерин Д. , Попов А.
Published: June 2021

В АО «Авиаавтоматика» им. В. В. Тарасова» создана технология изготовления многослойного углеродно-полимерного ионистора с применением передовых материалов. В статье рассмотрены особенности конструктивно-технологического исполнения, характеристики, сферы применения нового устройства, проведено сравнение с импортными аналогами.
КАК ПОВЫСИТЬ ЭФФЕКТИВНОСТЬ ЭЛЕКТРОМЕХАНИЧЕСКОГО ПРОИЗВОДСТВА
Authors: Иваненко А.
Published: June 2021

Описан процесс производства статоров низковольтных и высоковольтных двигателей с использованием современной автоматизированной линии. Отмечено, что описанное решение обеспечивает высокую эффективность производства и значительно увеличивает качество выпускаемых изделий.
УСКОРЕННЫЕ ИСПЫТАНИЯ НА СОХРАНЯЕМОСТЬ ЭЛЕКТРОННОЙ КОМПОНЕНТНОЙ БАЗЫ
Authors: Кулибаба А. , Савин А. , Юшин О.
Published: June 2021

Исследуется проблема отсутствия справочных данных для расчета коэффициента ускорения испытаний на сохраняемость электронной компонентной базы. Предлагается методика, основанная на анализе результатов ускоренных испытаний в разных режимах.
Robotic Automated External Defibrillator
Authors: K. R Dinesh.
Published: June 2021

India is one of the most populous countries of the world. Due to over population, ignorance of health has been remained the major problems in India. For every one minute a death, oops in because of heart attack. Ambulance service plays an important role in saving lives. Its primary purpose is to give first aid to the sick or injured people in the emergency scene. To save a life is auspicious as well as precious. The idea here is to provide an intelligent smart health system using some sensors and microcontrollers; it will sense the body condition and send the data to the collaborated hospital’s database. This proposed idea gives us the development of a wireless-based system for pulse rate, blood pressure and temperature monitoring to be used in ambulance. By this, the real time information can be passed to nearby hospitals to alert them about the critical conditions over IOT. This hardware device is fixed inside the ambulance to sense the patient’s health, collect the info during a wireless device called node MCU and immediately pass the database to the hospital’s server by the concept of IOT. This may intimate the hospital officials and should answer the required actions to be taken to the person in emergency.
The Role of Data Analytics in Kisan Credit Card for Sustainable Development
Authors: Tanna Vrutti
Published: June 2021

Agriculture is the main occupation in India as the large population is living in rural areas and having agriculture as their livelihood. According to the United Nations Development Programme, sustainable development in agriculture means national food security, upgrading the living standard of farmers, and conservation of the natural resources. The green revolution has called for high credit requirement for the purchase of high yielding seeds, irrigation systems, fertilizers, and chemical pesticides. Along with crop yields, the cost of production has raised drastically calling huge credit requirement. This huge credit requirement was not met by the cooperatives or commercial banks for their own limitations.The introduction of Kisan Credit Card (KCC) during the budget of 1998 has played a significant role in delivering the variable credit requirements in a flexible, easy, and timely credit The plan was launched by NABARD and Reserve Bank of India. The scheme aims to reduce farmer's dependency on informal banks for credit which is often lucrative yet very expensive. The card is offered by cooperative banks, regional rural banks, and public sector banks. Although KCC was a noble idea to help needy farmers, it has become a tool that is being misused by many, including people who are financially well off, and in this paper, we will discuss the misuse of Kisan credit card. The aim of this paper is to study the impact of Kisan credit card on agriculture development and how Kisan credit card has achieved sustainable development and what are the roadblocks still prevailing in achieving sustainable development and how the use of data analytics and artificial intelligence can help banks to provide Kisan credit card to farmers after analyzing their behavior and make sure that credit is being utilized only for agriculture development that can lead to sustainable development.
Geotechnical Applications of Sewage Sludge Stabilized with Biomass Ash and its Effect on Soil Nutriential Properties: A Critical Review
Authors: Yumnam Ishowriya
Published: June 2021

In this review article the usage of waste sewage sludge and the biomass ash for improving the engineering and non-engineering properties’ of both concrete and soil are discussed in detail. Numerous past research works were studied in detail so as to predict the behavior of biomass ash and waste sewage sludge when used for the stabilization process of soil and concrete. Past studies related to the usage of stabilized sewage sludge and biomass ash were studied in a detailed manner and depending upon the past studies several conclusions has been drawn which are discussed further. Several studies related to the usage of the waste sewage sludge for improving soil physical, chemical and biological properties showed that the usage of waste sewage sludge improve the physical properties, chemical properties, macro-nutriential properties and micro-nutriential properties up to a great extent. Depending upon the results of the past studies it can be concluded that the usage of sewage sludge has positive impact over all the properties of soil and this waste should be utilized in improving the properties of soil rather than dumping. Numerous studies related to the usage of the biomass ash showed that biomass ash has positive impact over both soil as well as concrete. Studies related to the usage of the biomass ash in soil showed that there was a positive response of the stabilized soil after its stabilization with the biomass ash. Studies related to the usage of the biomass ash in concrete showed that the biomass ash can be used up to 10 percent replacement of the ordinary Portland cement so as to attain maximum strength results from it.
Fake Image Detection
Authors: Shalini S.
Published: June 2021

In this technological generation, social media plays an important role in people’s daily life. Most of them share text, images and videos on social media(Instagram, Facebook, Twitter ,etc.,). Images are one of the common types of media share among users on social media. So, there is a chance for monitoring of images contained in social media. So most of the people can fabricate these images and disseminate them widely in a very short time, which treats the creditability of the news and public confidence in the means of social communication. So here this research has attempted to propose an approach which will extract image content, classify it and verify that the image is false or true and uncovers the manipulation. There are many unwanted contents in social media such as threats and forged images, which may cause many issues to the society and also national security. This approach aims to build a model that can be used to classify social media content to detect any threats and forged images.
Gambaran Rasionalitas Penggunaan Zinc dan Probiotik Pada Pasien Diare Pediatrik
Authors: Sammulia Suci Fitriani , Suhatri Suhatri , Safitri Susi
Published: June 2021

Penyakit diare sampai saat ini masih menjadi salah satu penyebab utama kesakitan dan kematian terbesar di dunia. Diare menyerang hampir seluruh usia, dan kebanyakan dialami oleh anak berusia di bawah lima tahun atau balita. Penatalaksanaan diare akut anak menurut World Gastroenterology Organisation terdiri dari terapi rehidrasi oral, terapi suplemen zinc, diet, probiotik, dan antibiotik. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan zinc dan probiotik pada pasien diare pediatrik yang dirawat di Rumah Sakit X Kota Batam periode 2017-2018. Penelitian ini dilakukan secara deskriptif retrospektif, data diperoleh dari rekam medik pasien. Sampel diambil sebanyak 61 rekam medik dengan purposive sampling. Hasil penelitian menunjukkan bahwa penderita diare didominasi oleh jenis kelamin laki-laki (33 pasien) dibanding perempuan (28 pasien) dengan kejadian tertinggi pada rentang usia 1 bulan- 12 bulan yakni (23 pasien). Persentase rasionalitas penggunaan zinc yaitu sebesar 67,21% dan tidak rasional sebesar 32,79%. Sementara itu, persentase rasionalitas penggunaan probiotik adalah sebesar 59,01% dan tidak rasional sebesar 40,98%.
Optimasi Proses Hidrolisis Protein Dari Limbah Bulu Ayam
Authors: Bowo Pangestu , Indrawati Teti , Rahmat Deni
Published: June 2021

Limbah bulu ayam yang mengandung protein keratin telah direkomendasikan sebagai sumber nutrisi alternatif yang dapat digunakan untuk pakan ternak, industri kosmetik, dan industri pupuk. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh konsentrasi NaOH terhadap kualitas hidrolisat bulu ayam. Penelitian dilakukan dengan optimasi proses hidrolisis limbah bulu ayam dengan metode basa menggunakan NaOH (rasio 1:6) dengan variasi konsentrasi 5%, 7,5% dan 10% selama 4 jam pada suhu 80ºC. Penentuan rendemen hidrolisat bulu ayam paling optimum dilakukan dengan analisis total protein menggunakan metode Kjeldahl, analisis asam amino dengan menggunakan Amino Acid Analyzer (AAA) dan identifikasi profil protein menggunakan metode Static light scattering (SLS). Hasil optimasi proses hidrolisis dapat disimpulkan bahwa hidrolisat bulu ayam dengan konsentrasi pelarut NaOH 5% menunjukkan hasil optimum dengan  rendemen sebesar 70,24% , total protein 62,66 %, total asam amino bebas 39.126 % dan masa molekul protein dengan metode SLS menunjukkan hasil 4,31 kDa.
Four Tier Test Ecosystem: Diagnostic Test to Detect Misconception on Ecosystem Concepts
Authors: Lintang  , Purwati Kuswarini Suprapto  , Ryan Ardiansyah
Published: June 2021

Background: This study aims to develop and produce a diagnostic tool capable of detecting student misconceptions on the concept of ecosystems. Methods: This study used a research and development method with a modified 4D design (Define, Design, Develop and Disseminate) without disseminating or spreading. Data collection methods used in this research and development are observation, literature review, documentation, questionnaires, interviews and tests. Results: The results showed that the instruments developed were valid by validating 3 experts, namely material experts, evaluation and assessment experts, and linguists with an average percentage of each feasibility of 90% material expert judgment, 82% assessment expert assessment and evaluation. and 80% linguist assessment. Meanwhile, the instrument readability test showed a percentage of 63% in good category. The validity value of the instrument in general was 0.70 with the valid or high validity category, while the instrument reliability value was 0.82 with the very high category of reliability. The overall results of students' misconceptions on ecosystem material showed 23% of students experienced low-category miconceptions, 8% of students experienced no conceptual understanding, 17% of students experienced conceptual understanding, and 52% of students experienced partial understanding. Conclusion: Based on these results it can be said that the four-tier test instrument developed is feasible and can diagnose misconceptions in students
Status, Conservation Efforts and Rare Ornamental Plants in Kota Banda Aceh and Aceh Besar District
Authors: Kiki Monita  , Ismul Huda  , Hasanuddin  , Fatilah Erni
Published: June 2021

Background: Ornamental plants have their charm and high economic value, but their population in nature is decreasing. This study aims to determine the types of rare ornamental plants, conservation status and conservation efforts. Methods: The methods used in this research are qualitative methods and exploratory surveys. The population in this study were all sellers/entrepreneurs of Decorative Garden Plants in Banda Aceh City and Aceh Besar District. The research period was eleven months, from September 2019 to August 2020. The data was collected through an exploratory survey, using the IUCN Red List application and semi-structural interviews. Interviews were conducted using a questionnaire, and descriptive statistical analysis was carried out for conservation efforts. The questionnaire contains questions about conservation efforts with available answer options to gather information related to research. Results: The results showed that the types of rare ornamental plants consist of 32 species, the conservation status is dominated by minimal concern (56%) composed of 14 families. Conclusions: Rare ornamental plants are easily found in Kota Banda Aceh and Aceh Besar District. There is still a lack of conservation efforts such as protection, cultivation in preserving rare/endangered ornamental plants.
Pelatihan untuk Meningkatan Semangat Green Entrepreneur pada Siswa Sekolah Menengah Atas
Authors: Etni Marliana  , Gilang Puspita Rini  , Faridhatun Faidah
Published: June 2021

Background: Green entrepreneur dibutuhkan untuk menjawab tantangan bisnis yang baru di abad 21. Adanya konsep green economy menuntut adanya lebih banyak wirausahawan yang membangun bisnis secara lebih berwawasan lingkungan. Metode: Pengabdian dilakukan dengan cara penyuluhan serta simulasi. Hasil: Hasil dari pengabdian ini adalah siswa dapat mempelajari karakteristik dari green entrepreneur, meningkatkan kreativitas dengan cara memproduksi barang menggunakan barang bekas, serta mempraktekkan menghitung biaya produksi dan harga pokok. Kesimpulan: sikap kreatif siswa terasah melalui simulasi pengolahan bahan bekas menjadi sesuatu yang bernilai ekonomis. Melalui simulasi tersebut siswa juga belajar cara menghitung biaya produksi dan harga pokok penjualan.
Pencegahan Penyakit Scabies di Lembaga Pemasyarakatan Perempuan Kelas II B Yogyakarta
Authors: Ubaidillah Ubaidillah
Published: June 2021

Background: Scabies adalah infeksi kulit yang disebabkan oleh tungau Sarcoptes scabiei berukuran kecil yang hidup di dalam kulit penderita. Ciri khas dari scabies adalah gatal-gatal hebat, yang biasanya semakin memburak pada malam hari Kondisi penjara yang kurang memadai tentunya menjadi faktor risiko timbulnya berbagai penyakit menular salah satunya adalah skabies. Tujuan dari acara pengabdian masyarakat ini adalah untuk memberikan edukasi yang tepat kepada penghuni Rutan tentang penyakit scabies serta untuk memberikan edukasi kepada penghuni Rutan tentang Sanitasi lingkungan dan Higiene perseorangan sebagai faktor penghambat terjadinya penularan scabies. Metode: Metode yang dilakukan adalah dengan memberikan pendidikan dan penyuluhan dengan menggunakan slide projector serta memberikan pertanyaan untuk menilai tingkat kepahaman audiens.   Hasil: Hasil yang didapatkan ketika diberikan pertanyaan, para audiens rata-rata menjawab dengan benar yang menandakan para audiens sudah mengerti akan arti pentingnya tentang Sanitasi lingkungan dan Higiene perseorangan. Kesimpulan: Terdapat peningkatan pengetahuan tentang scabies dan higiene dan sanitasi perseorangan.
Penerapan Teknologi Kesehatan Tepat Guna di Era Industri 4.0 dalam Perlindungan Anggrek Alam Terhadap Infeksi Penyakit di Kebun Raya
Authors: Mahfut Mahfut , Heningtyas Yunda , Sukimin
Published: June 2021

Keberadaan anggrek alam di Kebun Raya Liwa merupakan salah satu kekayaan flora asli Sumatera Bagian Selatan yang perlu dijaga kelestariannya. Berdasarkan hasil identifikasi diketahui bahwa beberapa individu anggrek menunjukkan gejala terinfeksi virus. Tujuan dari kegiatan pengabdian ini adalah untuk mencari metode pengendalian penyakit virus yang tepat, efektif, dan efisien. Metode yang dilakukan melalui pendekatan beberapa bidang ilmu seperti biologi, proteksi tanaman, dan ilmu komputer. Aplikasi induksi ketahanan agensia hayati mikoriza endofit sebagai agen biokontrol yang mampu menekan replikasi penyakit pada tanaman dapat digunakan sebagai cara yang murah dan ramah lingkungan dibandingkan pestisida. Selain itu, penggunaan metode sistem pakar diagnosis penyakit tanaman dengan metode case-base reasoning berbasis web. Pelaksanaan kegiatan pengabdian ini masih dalam masa pandemi Covid-19 sehingga sebagian besar kegiatan dilakukan secara daring (online). Keseluruhan metode identifikasi penyakit berbasis ilmu biologi, penyakit tanaman, dan ilmu komputer serta upaya pengendaliannya yang merupakan hasil produk (output) kegiatan pengabdian masyarakat ini diadopsi oleh pihak Kebun Raya Liwa sebagai upaya pengembangan dan pelestarian koleksi anggrek alam di era industri 4.0. Hasil evaluasi diperoleh peningkatan pengetahuan dan pemahaman peserta pelatihan dengan peningkatan sebesar 21,64 point (34,72%). Hasil kegiatan ini diharapkan tidak hanya sebatas peningkatan pengetahuan dan pemahaman dalam peserta kegiatan, tetapi juga dapat menerapkan dan menularkan pengetahuan yang diperoleh selama pelatihan kepada komunitas pecinta anggrek dan masyarakat luas.