bluuebunny/crossref_metadata_2025 huggingface dataset:
What does mash suffer from, or fungal diseases of the Vigna radiate
Authors: Kurkina Yu. N.
Published: December 2022

Relevance. Mash (Vigna radiate (L.) R.Wilczek) is a very ancient Asian legume plant, which, thanks to a number of advantages, may become an important vegetable crop in Russia. Young fruits and seeds of Vigna radiate are rich in protein, vitamins A, B, C, PP, iron, folic acid, and taste like green peas. A lot of essential amino acids and a low glycemic index make it possible to use even mature mash seeds for the preparation of dietary food. To preserve the harvest, it is important to know the diseases of the crop.

Methods. For a number of years, a sample of the radiant vigna VR-2014 (Vietnam) has been studied on a natural infectious background in the soil and climatic conditions of the Belgorod region (Russia). Field tests and mycological studies made it possible to determine the species composition of phytopathogenic microscopic fungi, describe the symptoms and compare the main elements of accounting for mycoses.

Results. The length of the growing season of the radiant vigna did not exceed 83 days, the appearance of seedlings was noted on 10-12 days from sowing, flowers – on 68-73 days. The height of the plants did not exceed 40 cm. Ascochytosis (the causative agent of Ascochyta boltschauseri) led to losses of 82% of seed productivity, with an average prevalence of 40% and the development of the disease of 2.5 points. Ascochitosis reduced the values of all elements of seed productivity: the length and number of fruits, the mass of 1000 seeds, but most of all (by 5 times) the weight of fruits and seeds from the plant decreased. Peronosporosis (the causative agent of Peronospora fabae) led to losses of seed productivity by 16%, root rot (the causative agent of Bipolaris australensis) and fomosis (the causative agent of Phoma diversispora) – by 17% and 11%, respectively. Spotting was the leading symptom of mycoses of Vigna radiate, and the most harmful phytopathogenic fungi were representatives of the ground-air group of pathogens.
Influence of predecessors, mineral fertilizers and humate on the infestation of crops with weeds and the yield of chicory roots
Authors: Vyutnova O. M. , Smirnova I. V. , Novikova I. A. , Maksimova K. S.
Published: December 2022

Relevance. For the cultivation of environmentally friendly products, the preservation of soil fertility and environmental protection, the question of the prospects for longterm use of various fertilizer systems is very important. With an acute shortage of manure, a mineral-biological fertilizer system is promising, when an estimated dose of mineral fertilizers is applied against the background of annually sown siderates. Such a system of fertilizer application makes it possible to increase yields, product quality, significantly reduce the shortage of organic matter in the soil, improve its structure and biological activity. The inclusion of the employed steam with the most effective precursors, doses of mineral macro and micro fertilizers and humic acids in the rowed link of crop rotation can reduce the contamination of crops and significantly increase the yield of root chicory root crops.

Materials and methods. The research was carried out in 2017-2021 located in the Rostov district of the Yaroslavl region.

Results. As a result of the conducted research, it was found that on turf-podzolic medium-loamy soils of the Non-Chernozem zone of the Russian Federation, it is economically feasible to use technology for the cultivation of root chicory using an oatpea mixture as a precursor in combination with the introduction of mineral fertilizers into the soil at a dose of N60P60K120 and the treatment of vegetative plants with boron and humate. When using this technology, the contamination of crops decreases, their photosynthetic potential and the yield of root crops increases, the cost of production decreases, and the profitability exceeds 104%.
Dependence of the performance of the reclaiming sewer cleaner with rigid guides from interchangeable bucket tools capabilities
Authors: Abdulmazhidov Kh. A.
Published: December 2022

Relevance. Cleaning of reclamation channels is a very relevant event. The need to clean the canals and maintain them in working condition becomes obvious during the flood period, when it is necessary to remove excess water. The paper presents mathematical models for determining the performance of the PP-303 canal cleaner, a feature of which is the rectilinear movement of the bucket on rigid guides along the bottom along the axis of the canal to be cleaned.

Methods. The article is formed on the basis of experimental research methods. The research was carried out based on experimental and calculated data. A network of drainage canals of the drainage system was taken as the research object, and the working equipment of the canal cleaner was taken as the research subject. Performance, which is the amount of products produced by the machine per unit of time, can be of three types (theoretical, technical, and operational) and can be determined with consideration of the design parameters of the working equipment. During the operation of trench cutting machines, their performance directly depends on the main parameter, namely, the depth of the canal being built; in the case of canal cleaning with canal cleaners, this parameter cannot be considered as the main one. This is due to the fact that siltation and sediments accumulating on the bottom and slopes of the canals during the operation of the reclamation system are extremely unevenly distributed along the length of the canal. The highest concentration and amount of sediments and siltation is observed mainly at the mouth of the canals, the junctions of canals of different levels, and the junctions of the drainage with the drainage canal. In this case, the most significant parameter is the thickness of the chips removed from the bottom and slopes of the canal by the bucket.

Results. The results of the research showed that the performance of the channel cleaner, as a batch machine, is influenced by the very design of the working equipment, the main element of which is a bucket capable of moving in a straight line along rigid guides at different speeds. With obvious high values of the performance of continuous channel cleaning machines, it can be concluded that the channel cleaner RR-303 showed high values of technical and operational characteristics, mainly due to the use of a trapezoidal profile bucket.
Diversity of the VIR basil (Ocimum basilicum L.) collection by morphological and phenological features
Authors: Kurina A. B.
Published: December 2022

Relevance. Basil is one of the most popular aromatic plants grown in the world. Various species and forms of Ocimum spp. differ in the nature of growth, color and aromatic composition. The VIR basil collection is represented by 452 accessions of six species from 55 countries. The expansion of the assortment of basil, as well as the identification of competitive adaptive cultivars with high economically valuable traits, determines the need to study and identify promising species and forms of Ocimum spp. The purpose of our work was to study accessions of basil (Ocimum basilicum) from the VIR collection by morphological and phenological traits and to identify accessions that have a complex of economically valuable traits for further use in the breeding.

Materials and methods. The studies were carried out at the Federal Research Center N. I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) at the VIR Pushkin and Pavlovsk Laboratories in 2019-2021 in open ground conditions. The material of the study was 66 accessions of the VIR basil collection of various agrobiological status and ecological and geographical origin. When analyzing the material, phenological observations, biometric measurements and morphological description of plants were carried out. These measurements were carried out in the phase of mass flowering.

Results. As a result of the study, the degree of variability of the main phenological and morphological features was revealed. Accessions of basil were selected according to such traits as early maturity, plant height, weight of one plant and cold resistance, which can be used as starting material for breeding. The studied accessions are grouped into 7 varieties of two subspecies (subsp. basilicum and subsp. minimum): var. basilicum, var. glabratum, var. purpurescens, var. majus, var. diforme, var. minimum and var. chamaeleonicum, and their characteristics are given.
Selection of cucumber for parthenocarpy for spring greenhouses
Authors: Korottseva I. B. , Belov S. N.
Published: December 2022

Scientific relevance. Currently, in the protected ground, the main areas are occupied by parthenocarpic hybrids of cucumber of foreign origin. Therefore, the selection of domestic cucumber hybrids of the parthenocarpic type is very relevant.

Material and conditions. The experience was laid in 2018-2022 in the Odintsovo district of the Moscow region in the conditions of a spring film ground greenhouse of the "Block" type on the basis of the head institution of the FSBSI FSVC. Agrotechnics of cultivation is generally accepted for the conditions of spring film greenhouses. In breeding nurseries where there were no bees, the degree of parthenocarpy was determined as the ratio of the fruit set to the number of female flowers formed on the plant, as a percentage. The records were carried out from the 5th to the 20th node inclusive, only on plants of the female type of flowering. On the basis of the laboratory of breeding and seed production of pumpkin crops, 27 collectible and more than 50 breeding samples of parthenocarpic cucumber were studied.

Results. During three years of research, 7 hybrids of cucumber of the parthenocarpic type of foreign breeding were selected based on the sum of economically useful traits.These hybrids were distinguished by a high degree of parthenocarpy. With their participation, as a result of multiple selections and self-pollination, more than 50 breeding lines were created. Analysis of the obtained material showed that the degree of manifestation of parthenocarpy on the plant (the arithmetic mean between the indicators of parthenocarpy on the main and lateral shoots) in the best half of the samples in 2021 was in the range of 30-50%, whereas in 2022 it already reached 50-70%. The parthenocarpy severity coefficient above 70% was noted only in 2022 in 4% of samples. About half of the samples showed a fairly low parthenocarpy: in 2021 no more than 30%, and in 2022 no more than 50%. Most of them were rejected. The parthenocarpy of the best breeding samples in 2022, compared with 2021, increased by an average of 17.7%. Breeding lines obtained even from the same collection sample often differed greatly, sometimes by 4 times, in the degree of parthenocarpy. The families of the most stable parthenocarpy samples had differences on this basis in 2021 only 3-6%, and in 2022 – 10-11%. Families with the greatest severity of this trait were selected annually. It can be concluded that the degree of parthenocarpy in cucumber strongly depends on both the genotype of the sample and the growing conditions. 3 breeding lines were selected, characterized by high indicators of the degree of manifestation of parthenocarpy in 2021 (61.5-70.5%) and the stability of the manifestation of this trait by families and years.
Use of prolonged-acting fertilizers in growing garden strawberry seedlings
Authors: Akimova S. V. , Matsneva A. E. , Marchenko L. A. , Solovyov A. V. , Zubkov A. V. , Bulanov A. E. , Arkaev D. S.
Published: December 2022

Timeliness. Currently, the Russian Federation has a high demand in healthy planting material of garden strawberries. The benefits of using fertilizers when growing strawberry seedlings have been proven by numerous studies. However, a comparative study of the effect of new fertilizers and methods of their application is very limited. In this regard, studies aimed at identifying the effectiveness of the use of prolonged-acting fertilizers in the production of garden strawberry planting material in protected soil conditions are relevant.

Methods. Adapted to non-sterile conditions, ex vitro healthy garden strawberry plants were planted in a peat substrate of Veltorf LLC (recipe No. 5c/2) with the addition of Pg mix starter fertilizer with the structure NPK 14-16-18 + microelements (1.5 g/l of substrate). At the same time, prolonged-acting fertilizers were introduced into the substrate in the recommended concentrations: FertiPro Gran 1M (1.25 g/l of substrate), Ruscote 5-6M (3.0 g/l of substrate), Basacote Plus 6M (4.0 g/l of substrate), control peat substrate without fertilizers, PG mix standard.

Results. It has been established that for the Karmen crop with an average runner-forming ability, the effectiveness of applying FertiPro Gran 1M fertilizer to the substrate was revealed, with the use of which, on the 180th day of cultivation, the number of runners and rosettes increases by 3.5–3.8 times compared to the control. At the same time, the yield of marketable seedlings is 95% compared to 70% in the control. For the Jūnija smaids crop with a high vine-forming ability, the effectiveness of all experimental variants with the application of FertiPro Gran 1M, Ruscote and Basacote Plus fertilizers to the substrate was revealed, with the use of which, on the 180th day of cultivation, the number of runners and rosettes increases by 1,9-2,5 times compared to the control. At the same time, the yield of marketable seedlings is 94-96% compared to 65% in the control.

Conclusion. The introduction of long–acting fertilizers FertiPro Gran, Ruscote and Basacote Plus into the peat substrate with the addition of Pg mix starter fertilizer allowed a 2.3 – 3.8-fold increase in the number of runners obtained and 1.9-3.5-fold increase in the number of sockets obtained compared to the control without fertilizers.
From the GAs: Congratulations, Publications, Presentations
Authors: Creel Stacy , Welsh Teresa
Published: December 2022

Updates on USM SLIS alumni, faculty, and students.
Federal Depository Library Program (FDLP) Academic Library Websites A webometric analysis of academic libraries participating in the FDLP
Authors: Isenhower Leah
Published: December 2022

The purpose of this study is to evaluate the website content of academic libraries participating as selective depositories in the FDLP to examine legal compliance and accessibility to electronic government information.
Dimensiones del aprendizaje colaborativo docente en Comunidades Profesionales de Aprendizaje en Chile
Authors: Peña Ruz Marcela
Published: December 2022

La colaboración docente en las últimas décadas ha adquirido cada vez más importancia como estrategia para la mejora e innovación escolar (Hargreaves & O’Connor, 2020). Una Comunidad Profesional de Aprendizaje (CPA) pone énfasis en el desarrollo de culturas colaborativas que incentivan el aprendizaje, tanto en los docentes como en los estudiantes (Bolam et al., 2007; Hord et al., 2010; Hord & Hirsh, 2008). El presente estudio analiza las apreciaciones de docentes, directivos y asistentes de la educación sobre las dimensiones de colaboración que contempla una CPA. El método de investigación corresponde a un estudio mixto concurrente (Creswell, 2009) con estrategia de estudio de casos múltiples (Stake, 1998) en cinco centros educativos de Chile. Se aplicó un cuestionario a 161 informantes, junto al desarrollo de 10 grupos de discusión. Los principales hallazgos establecen que son positivas las percepciones con respecto a las relaciones entre pares al compartir sus prácticas, sin embargo, se carece de espacios de acompañamiento, observación y retroalimentación entre pares que permitan profundizar en el aprendizaje colectivo. Se observa la necesidad de avanzar en espacios de profundización especializada en la práctica docente, teniendo como base la documentación de investigaciones en materias educativas, junto con potenciar las fortalezas halladas en los centros educativos con relaciones sociales positivas para el aprendizaje.
Gamificación para captar la atención de niños aprendices en la clase de inglés
Authors: Barbosa Alfonso Luisa Fernanda , Dueñez Castro Juliana , Patiño Flórez Diana , Castellanos Jaimes Judith
Published: December 2022

En esta investigación- acción, nuestro propósito fue realizar una intervención pedagógica en la clase de inglés utilizando el método de Gamificación con niños de grado primero en un colegio bilingüe de educación privada. En el análisis de necesidades identificamos aspectos que afectan el aprendizaje como falta de motivación o desinterés y bajo desarrollo en habilidades de escucha y habla. El estudio se basa en las preguntas ¿Cómo apoya la Gamificación las habilidades de inglés de los niños? y ¿Cuál es el papel de la gamificación en el compromiso de los estudiantes? Nos centramos en tres constructos teóricos: aprendizaje significativo, niños aprendices y gamificación, teniendo en cuenta autores como Rieber (1996); Delgado y Breña, (2022), Ospina (2006), entre otros. Al analizar notas de campo y transcripciones de videos, los resultados muestran que hubo participación activa, aprendizaje continuo de los estudiantes, mayor interés por explorar, y seguridad para preguntar temas desconocidos sin temor. Se evidenció el desarrollo de las habilidades de escucha y habla al reconocer, pronunciar y asociar significados en inglés y español. Los niños expresaron sus conocimientos, trabajaron en equipo con sus compañeros y hubo compromiso por parte de los estudiantes
बेचबिखन विरूद्धका भ्रामक रणनीतिहरूबाट जोखिममा रहेका नेपाली महिलाहरू
Authors:   Institute of Development Studies, Oosterhoff Pauline , Snyder Karen , Sharma Neelam
Published: December 2022

ेपालमा अतिथि सत्कार, मनोरञ्जन र कल्याण सम्बन्धी उद्योगहरू बढ्दै गएका छन्। बेचबिखन विरूद्धका प्रयासहरूमा प्रयोग गरिएको लेबल ‘वयस्क मनोरञ्जन क्षेत्र’ (‘AES’) ले यी उद्योगहरूमा के ही व्यवसायका मालिकहरू र मुख्यतया महिला कामदारहरूको प्रतिष्ठामा दाग लगाएको छ। व्यवसायहरूलाई कर््मचारीहरू खोज्न र कामदारहरूलाई काम खोज्नमा मद्दत गर्ने श्रम मध्यस््थकर््तताहरू यी अनौपचारिक उद्योगहरूको महत्त्वपूर््ण र प्रायजसो गलत रूपमा प्रस्तुत हुने अंश हुन्। महिलाहरूसँग नेपालमा सुरक्षित रोजगारी वा वैदेशिक श्रम आप्रवासनका लागि कु नै विकल्प नरहेको अवस््थथा रहेको छ। यी व्यवसाय र सामाजिक सुरक्षाको सजिलो दर््तता तथा अनुगमनलाई सहायता गर््ननाले नेपालको अर््थतन्त्रमा सुधार आउने छ र काम गर्ने अवस््थथाहरू अझै राम्रो हुनेछन्।
The Trilogy of Linguistic Communication of the Qur’an Surah Al-Kâfirûn
Authors: Chaer Hasanuddin , Rasyad Abdul , Sirulhaq Ahmad , Malik Djamil Abdurachman
Published: December 2022

In Indonesia, the word "al-kâfir" which comes from the Arabic word "al-kâfir" (الكافر) as in the Qur'an surah al-Kâfirûn is often used to offend non-Muslim groups. This study aims to reveal the essence of the meaning of linguistic features in the form of the main word "al-kâfir" and sentence in the first verse of surah al-Kâfirûn, which is still ambiguous, as the word "kâfir" is often only interpreted to non-Muslim people. This study used Jakobson's "interlingual" linguistic translation theory with the "mutual translatability" analysis method. These methods reveal aspects of the equivalent of words and sentences from the source language of the Qur'an to the target language (Indonesian). This study found that the word al-kafir in the first verse of al-Kâfirûn does not only mean to people who are not Muslim but contains meaning to all individuals who are blind to the truth of the Qur'an. Allah taught the linguistics of the Qur'an through Muhammad to all individuals. Thus Allah teaches the meaning of effective and persuasive communication through the trilogy of linguistic communication of surah al-Kâfirûn. As an implication, this finding is expected to reduce the gap in understanding the word "al-Kâfirûn," which sometimes triggers social conflict.
The Trinity, Sexuality, and Gender In Sarah Coakley's Thought
Authors: Susanta Yohanes Krismantyo , Yordani Yeremia
Published: December 2022

This paper focuses on the thoughts of Sarah Coakley who tried to enter into dialogue with the concepts of the trinity, sexuality, and gender. According to Coakley, the root cause of sexuality and gender lies in desire (eros). Coakley made a strong critique of Sigmund Freud's thinking. If it was Freud who said the desire for God is was really about sex, on the other hand, Coakley asserted, sexual desire is was always about the desire for God. Coakley approaches the reality of the Trinity and relates it to the problem of human desire through contemplation. The practice of contemplation provides clues about how one can transcend existing gender and sexuality stereotypes. The contemplation that is at the heart of Coakley's thinking plays a very important role in approaching the Trinity, and from there he addresses issues of sexuality and gender.
Gestalt İlkeleri Bağlamında Tarihi Yapı Cephelerinin Görsel Algılanabilirliği: Tarsus Örneği
Authors: Deniz Merve , Tokman Leyla Yekdane
Published: December 2022

Tarsus kenti; çeşitli toplumların hâkimiyet kurduğu bir bölge olduğundan yerleşimin oldukça tarihi bir dokusu bulunmaktadır. Ancak birçok nitelikli yapı, zamanla çeşitli müdahaleler yaşamış ve bu yapıların cephe elemanları yenilenmiştir. Bu çalışmanın amacı müdahaleler sonrasında yenilenen tarihi yapı cephelerinin görsel algılanabilirliklerini Gestalt İlkeleri bağlamında değerlendirmektir. Öncelikle araştırmaya konu olan 10 adet tarihi yapı yerinde incelenmiş ardından cephelerin görsel algılanabilirliklerini değerlendirmek için cephe yüzeysel analizleri yapılmıştır. Yapılan çalışmalar ile Yeni Hamam’ın, güney cephesindeki kesme taşların geçirdiği müdahaleler neticesinde kapatılarak boyandığı ve bu durumun cephenin özgünlüğünü yitirmesine yol açtığından görsel algıyı zedelediği; diğer yapıların ise görsel algılanabilirliklerinin güçlü olduğu sonucuna varılmıştır. Dolayısıyla ilerleyen süreçlerde bu yapıların cephelerinde meydana gelecek herhangi bir tahribat yapıların görsel algılanmalarına zarar vereceğinden tek yapı ölçeğinde ziyade bütüncül bir koruma yaklaşımının gözetildiği kültürel rota önerisi geliştirilmiştir. Rota kapsamında yer alan Yeni Hamam’ın kapatılan kesme taşları tekrardan gün yüzüne çıkarılıp görsel algılanabilirliği devam ettirilmelidir. Öteki yapılarda ise belirli periyodlarla bakım-onarım faaliyetleri yapılmalıdır. Bu sayede yapıların hem sistemli bir biçimde ziyaret edileceğinden daha az bozulacağı hem de bakım-onarım faaliyetleri ile cephelerdeki bozulmalarının önleneceği böylelikle görsel algının sürdürülebileceği öngörülmektedir.
The Effects of BTTN, TMETN and DEGDN Molecules on the Explosion Properties of PETN Molecule
Authors: Hilal Cihat , Varış Serhat , Mert Mehmet Erman , Önal Müşerref , Sarıkaya Yüksel
Published: December 2022

Molecular modelling is an appreciated tool that brings valuable data on physical and chemical characteristics of materials that eliminates the necessity of conducting any experiment. This method allows to calculate the performance of energetic molecules to be synthesized. In the work, the detonation parameters of the energetic organic compounds Pentaerythritol tetranitrate(PETN), Butanetriol trinitrate (BTTN), Trimetylolethane trinitrate (TMETN) and Diethyleneglycol dinitrate (DEGDN) has theoretically been calculated and some values compared with the literature values. Moreover, three hypothetical molecules combining PETN with other explosive molecules have been designed. The detonation properties have been calculated using density functional theory (DFT) with B3LYP/6-31G (d,p) basis set. It has been concluded that all molecules have the effect of increasing the explosion parameters of PETN.
Prevalence of Fungal Disease Agents in Garlic Growing Areas of Gaziantep Province
Authors: Yıldızbakan Nuran , Atakan Aydin , Özgönen Özkaya Hülya
Published: December 2022

Surveys were carried out in garlic cultivation areas of Gaziantep province in April 2018 and April 2019 to determine the prevalence of fungal diseases of garlic. After the isolation process was conducted according to routine mycological methods, fungi were identified according to their cultural and morphological characteristics. Fungi belonging to genera of Fusarium, Rhizoctonia, Macrophomina and Puccinia were determined in garlic production areas. The most prevalent genus among all fungi was determined as the Fusarium isolated from all areas. The rust disease caused by Puccinia porri has not been detected in the Islahiye district and its prevalence in other areas varies between 5,1-18 %.
IPCC Tier 1 ve DEFRA Metotları ile Karbon Ayak İzinin Belirlenmesi: Erzincan Binali Yıldırım Üniversitesi’nin Yakıt ve Elektrik Tüketimi Örneği
Authors: Kurnuç Seyhan Aslıhan , Çerçi Muhammed
Published: December 2022

Bu çalışmada Erzincan Binali Yıldırım Üniversitesi (EBYÜ)’nin 2019 ve 2020 yılına ait karbon ayak izi önce Hükümetler arası İklim Değişikliği Paneli (The Intergovernmental Panel on Climate Change–IPCC) Tier 1 yaklaşımıyla sonrasında ise İngiltere Çevre, Gıda ve Köy işleri Bakanlığı (Department for Environment, Food and Rural Affairs–DEFRA) dönüşüm faktörleri kullanılarak hesaplanmıştır. EBYÜ’nün birincil karbon ayak izi IPCC Metodolojisi Tier 1 yaklaşımıyla 2019 yılı için 2753,2 tCO2e ve 2020 yılı için 2383,74 tCO2e emisyonu hesaplanmıştır.2019 yılı ile karşılaştırıldığında emisyon miktarında %13,42 azalma görülmektedir. DEFRA dönüşüm faktörleriyle ise 2019 yılı için 2314,53 tCO2e ve 2020 yılı için 1826,54 tCO2e emisyonu hesaplanmıştır. 2019 yılı ile karşılaştırıldığında emisyon miktarında %21,08 azalma görülmektedir. IPCC Tier 1 yaklaşımı ile DEFRA arasındaki bu fark IPCC Tier 1 yaklaşımı hesaplamalarında kullanılan emisyon faktörlerinin genel olması ve DEFRA’nın İngiltere’nin ulusal verilerini kullanmasından kaynaklanmaktadır. Karbondioksit emisyonundaki azalmaya 2019 yılına kıyasla 2020 yılında iklimin biraz ılımanlaşmasının yanı sıra Covid-19 pandemi süreci nedeniyle 2020 yılında eğitim-öğretime uzaktan eğitimle devam edilmesinin etki ettiği düşünülmektedir.
D/L-Homosistein Tamoksifene Dirençli MCF-7/TAMR-1 Meme Kanseri Hücrelerinin Proliferatif Özelliklerini ER Stresi Aracılı Olarak Baskılayabilir
Authors: Erzurumlu Yalçın , Doğan Hatice Kübra
Published: December 2022

Tamoksifen meme kanseri tedavisinde sıklıkla kullanılan ancak reseptör ifade profillerindeki değişimlere bağlı olarak kullanımı sınırlanan önemli bir tedavi yaklaşımıdır. Her ne kadar tamoksifen klinikte yoğun bir uygulama alanına sahip olsa da meme kanseri hastalarının %20-30'u çeşitli nedenlerle de novo veya tedavi sonrasında tamoksifene karşı direnç geliştirmektedir. Meme kanseri, dünya genelinde kadınlar arasında kansere bağlı ölümlerin ikinci nedenidir ve her yıl birçok kişi meme kanseri nedeniyle yaşamını yitirmektedir. Bu nedenle meme kanseri hücrelerinin tamoksifen duyarlılığını arttırmak üzerine çok sayıda çalışma sürdürülmektedir. Son çalışmalar, endoplazmik retikulum (ER) stresine ilişkin mekanizmaların meme kanserinin ilerlemesinde ve kazanılmış ilaç direncinde önemli anahtar düzenleyiciler olduğuna işaret etmiştir. Bu nedenle ER stresini modüle eden ajanlar meme kanserine yönelik geliştirilecek yeni tedavi yaklaşımları için yoğun olarak araştırılmaktadır. Çalışmalarımızda D/L-homosistein’in tamoksifen ile kombine uygulamasının in vitro da tamoksifene direnç gelişimini iyi mimik eden MCF-7/TAMR-1 hücrelerinde ER stresi modülasyonu yolu ile tamoksifen duyarlılığını geliştirdiği belirlenmiştir. Çalışmamızdan elde edilen bulgular meme kanserinde ER stresi ile ilişkili süreçlere etki edebilecek yeni moleküllerin tamoksifen ile kombine edilerek tamoksifen direncine karşı uygulanacak alternatif yaklaşımlar açısından umut vaat ettiğini önermektedir.
THE USE OF TRANSCUTANEOUS SUPRAORBITAL NERVE STIMULATION IN THE TREATMENT OF ASTHENIC SYNDROME AFTER COVID-19
Authors: Nedogoda S. V. , Vlasov Daniil S. , Ledyaeva Alla A. , Salasyuk Alla S. , Chumachek Elena V. , Tsoma Vera V. , Lutova Victoria O. , Popova Ekaterina A. , Bychkova Olga I. , Labaznikova Victoria A. , Evdokimov Konstantin S.
Published: December 2022

Resume. Aim: to assess the efficacy of Transcutaneous Supraorbital Nerve Stimulation (t-SNS) with the Cefaly® Device on the parameters of asthenia and anxiety, as the main components of psychosomatic changes after suffering COVID-19. Materials and methods: an open prospective study in parallel groups was conducted. 60 patients, 30 men and 30 women, average age (61,3 ± 4,1) years, after a coronavirus infection (COVID-19) more than 6 months ago, meeting the following criteria: age from 60 to 75 years old, presence of asthenic syndrome, no contraindications to supraorbital neurostimulation was included. By the envelope method, patients were randomized into two groups. In the Cefaly® group (30 people), patients underwent 10 procedures (3 times a week) of t-SNS with the Cefaly® Device (Cefaly Technology sprl, Herstal, Belgium) in combination with restorative treatment according to temporary methodological guidelines for medical rehabilitation for a new coronavirus infection (COVID-19), in the control group (30 people), patients received only rehabilitation treatment. The results were evaluated using the Multidimensional Fatigue Inventory (MFI-20) and the Hamilton Anxiety Rating Scale (HAM-A) at baseline and after 24 days of therapy. Results: Cefaly® in addition to the standard rehabilitation program effectively reduces the severity of asthenia symptoms -in the Cefaly® group it was 33,6 %, in the control group - 14,4 %. The use of Cefaly® affects all components of the asthenic syndrome (reduced activity, reduced motivation, physical and mental asthenia). The standard rehabilitation program had an effect only on physical asthenia and reduced activity, but not on parameters of reduced motivation and mental asthenia. The reduction in total score from baseline on the HAM-A anxiety scale in the Cefaly® group was 55,16%, in control group -19,74 %. Cefaly® therapy had the greatest effect on insomnia and tension. It should be noted that the standard rehabilitation program has little effect on anxiety scores. However, after treatment, both groups maintained a high mean total asthenia score (MFI-20 - 42,5 points in the Cefaly® group, 63 points in the control group), which once again confirms that post-COVID changes (Long COVID) are long-term in nature even with availability of adequate therapy. Conclusions: The use of transcutaneous supraorbital nerve stimulation can more effectively reduce the severity of symptoms of asthenia and anxiety in people who have recovered from COVID-19.
CLINICAL SURVEILLANCE AND MONITORING OF PATIENTS TREATED FOR SPONTANEOUS PNEUMOTHORAX ASSOCIATED WITH LUNG DAMAGE CAUSED BY CORONAVIRUS-RELATED INFECTION (COVID-19)
Authors: Salimov Dmitry Sh. , Vorobyov Alexander A. , Vedenin Yuri I. , Glushkov Ilya V. , Kraynyukov Pavel E.
Published: December 2022

Spontaneous pneumothorax associated with COVID-19-related lung damage can result in a more severe course of the disease with a high probability of lethal outcomes. A multicenter, retrospective study, which involved 1356 patients with COVID-19-induced pneumonia, was conducted. 17 patients (1,25%) developed pneumothorax. COVID-19-associated pneumothorax results in increased length of hospital stay, dictates the need for active surgical management and contributes to a higher mortality rate especially in elderly patients.
PROGNOSTIC SIGNIFICANCE OF COMORBIDITY IN ASSESSING THE DURATION OF INPATIENT TREATMENT IN PATIENTS WITH PERFORATED ULCER
Authors: Suvorov Vladimir A. , Panin Stanislav I. , Kovalenko Nadezhda V. , Postolov Mikhail P. , Mikhin Evgeny S. , Peshkurova Irina A.
Published: December 2022

Resume. Aim of the study. To assess the effect of perioperative factors on the duration of postoperative inpatient treatment of patients with perforated ulcers in conditions of different comorbidity. Material and methods. A study of the results of surgical treatment with a perforated ulcer was conducted in 194 patients. Group 1 included 57 patients (29 %) with a Charlson - Deyo comorbidity index of 0-2 points, group 2-77 patients (40 %) with a comorbidity index of 3-4 and group 3-60 patients (31 %). The Charlson - Deyo comorbidity index > 4 points. Paired and multiple linear regression were used to predict the duration of postoperative treatment. Results. The duration of the postoperative period in the first group was 9 [8-10] days, in the second group - 8 [7-9] days, in the third group - 10 [7-18] days (p < 0,001). Correlation between the level of comorbidity on the Charlson - Deyo scale straight, high closeness (p = 0,703), statistically significant (p < 0,001). In multivariate models for all levels of comorbidity, the significant regressor of the duration of postoperative inpatient treatment was the duration of surgery and the degree of complications according to Clavien - Dindo. In addition, in group 1, the factors were total blood bilirubin and perforation diameter, in group 3 - age, blood creatinine level and perforation diameter. Conclusion. Taking into account the comorbid status in the stratification of patients makes it possible to predict the duration of inpatient treatment of patients with perforated ulcers.
A RARE OBSERVATION OF SMALL INTESTINAL TUBULAR ADENOCARCINOMA WITH A NEUROENDOCRINE COMPONENT
Authors: Todorov Sergey S. , Todorov(Jr.) Sergey S. , Deribas Victoria Yu. , Kazmin Andrey S. , Fomchencova Yulia M.
Published: December 2022

Аbstract. Neoplasia of the small intestine are extremely rare. A special place is occupied by tubular adenocarcinomas of the small intestine with a neuroendocrine component, the intravital diagnosis of which is difficult. Materials and methods. The paper presents a clinical observation of a 61-year-old patient who after resection of the small intestine was found to have tubuLar adenocarcinoma with a neuroendocrine component. Results. Morphoimmunohistochemical examination of the tumor revealed tubular adenocarcinoma with a neuroendocrine component (chromogranin A+, NSE+, aLcian+) with invasion into the subserous base. Conclusions. Tubular adenocarcinoma of the small intestine with a neuroendocrine component is a rare neoplasm of the gastrointestinal tract. In vivo pathoanatomical diagnosis of an intestinal tumor should include morphological, histochemical, immunohistochemical studies with the detection of tumor neuroendocrine cells and assessment of malignant potential.
The Injustice Facing Latino Immigrants in Achieving The American Dream in Cristina Heriquez’s Novel The Book of Unknown
Authors: Sandjojo Cintia Aaliyah , Basuki Imam , Kusumayanti Dina Dyah
Published: December 2022

United States of America is known as a country that promises its people or immigrants who come to America to become successful by providing ‘American Dream’ as the country’s national ethos. These people are given equal chances to bring out their dreams and aspirations. However, American Dream is not always the dream for everyone as experienced by the characters in Christina Henriques’ novel The Book of Unknown Americans. Issue of injustice shadows immigrants who are in search of this dream. Facing problems of injustice such as racism, different treatment of immigrants, and sexual harassment are inevitable for these Latino people when they first come to the United States. This study is aimed at discussing the failures and injustices that Latino immigrants’ characters of the novel must face when they attempt of achieving the American Dream. The method used in this study is qualitative method. The data of this research are in the forms of language and its discourse. Stuart Hall’s Theory of Representation is used to analyze the research data.  The results of this study show that not all-American dreams can be fulfilled easily, in particular for Latino immigrant characters in the novel. What have been faced by these characters are significant experiences to learn for anyone who wants to pursue their dream in United States of America.
Análise da proteção atribuída ao complexo fepasa em Jundiaí (SP) cotejada com as diretrizes de preservação
Authors: Silva Milena Meira da , Oliveira Eduardo Romero de
Published: December 2022

Neste estudo se propôs levantar dados da condição do Complexo Fepasa em Jundiaí-SP, enquanto bem ferroviário protegido por meio de tombamento decretado pelo Instituto do Patrimônio Histórico e Artístico Nacional (Iphan), a fim de cotejar com diretrizes existentes sobre conservação do patrimônio, especificamente o da tipologia industrial. Para isso foram analisadas sete diferentes cartas patrimoniais que orientam quanto à preservação do patrimônio cultural, cotejadas com as motivações que levaram ao decreto do tombamento, justificativas do corpo técnico e valorações consideradas na proteção do bem. Realizou-se consulta a livros e documentos públicos, além do auxílio na identificação de bens por meio de Sistema de Informação Geográfica (SIG). Ao fim, identificou-se que apesar de algumas iniciativas condizentes com as recomendações de preservação ao patrimônio, ainda falta diversidade e orientação no órgão de preservação na figura de seu corpo técnico quanto à proteção, conservação e identificação de valorações especificamente voltadas ao patrimônio industrial ferroviário.
Gamificação e aprendizagem
Authors: Céfalo Matheus Luiz de Souza
Published: December 2022

COSTA, M. A. F. da. Ensino de História e Games: dimensões práticas em sala de aula. 1. ed. Curitiba: Appris, 2017. 125 p.
Evaluation of food commercialization parameters in retail stores to support interventions in the food environment
Authors: Sanches Lucas Daniel , Lopes Renata Fagundes , Oliveira Maria Aparecida de , Martins Paula Andrea
Published: December 2022

Interventions in retail food stores, focused on the consumer based on social marketing strategies and also focused on storeowners based on strategies to support establishments, have shown to be promising in changing consumer behavior and promoting healthy eating. For an appropriate intervention, a proper diagnosis of the stores is needed, identifying characteristics that may facilitate or hamper an intervention implementation. Thus, this study aims to evaluate the parameters of food commercialization in retail food stores. This is a cross-sectional study, in which 9 retail food stores of low-income regions were assessed, at Santos city. To evaluate such stores, an instrument with 48 questions was developed and validated. As a result, fruits and vegetables were more frequently acquired through the self-purchase mechanism, and whole foods were received via food distributors. Fruit acquisitions were more frequent (1-3 x/week) than wholegrain foods procurements (1-2 x/month), what can be explained by the food groups’ distinct perishability. Regarding profitability degree, fruits and vegetables had smaller scores than those of whole foods. Evaluating commercialization parameters is useful for developing interventions to make retail food stores healthier, increasing exposure to healthy foods and, from there, contribute to changing consumer behavior. In addition, it can contribute to promoting public policies to strengthen retail food stores, which are important to the habits and food consumption in Brazil.
Comida de quilombo e a desnutrição infantil na Amazônia Paraense
Authors: Corrêa Nadia Alinne Fernandes , Silva Hilton Pereira da
Published: December 2022

As comunidades quilombolas enfrentam historicamente situações de vulnerabilidade, racismo e violência, isso têm refletido na organização social desses grupos, a ponto de configurar um estado grave de insegurança alimentar e nutricional. Este artigo analisa os níveis de vulnerabilidade em desnutrição de crianças quilombolas e não quilombolas no Estado do Pará, com idade abaixo de cinco anos, incluídas no Programa Bolsa Família. Trata-se de uma pesquisa empírica, quantitativa, com dados provenientes do Mapeamento da Insegurança Alimentar e Nutricional (Mapa InSan 2018). Os resultados indicam que a desnutrição é elevada segundo estatura-por-idade (36,1%) e peso-por-idade (8,4%), o que sugere que uma criança que não pertence a nenhuma comunidade tradicional tem 85% mais chances de viver em melhores condições do que uma criança quilombola no estado do Pará. A prevalência da insegurança alimentar e nutricional é ainda maior nos territórios quilombolas, o que reforça a vulnerabilidade dessa população.
Análise macroscópica de nascentes protegidas por meio da técnica solo-cimento nos municípios de Campo Mourão e Luiziana, PR
Authors: Athaydes Tiago Vinicius Silva , Parolin Mauro , Crispim Jefferson de Queiroz
Published: December 2022

Garantir água de qualidade é tema presente na realidade brasileira, uma vez que o país carece de práticas universais para o saneamento básico, especialmente no meio rural. Portanto, o objetivo deste trabalho foi de realizar análise macroscópica em nascentes protegidas por meio da técnica do Solo-cimento que são utilizadas para o consumo humano em propriedades rurais nos municípios de Campo Mourão e Luiziana. A análise macroscópica segue a metodologia organizada por um checklist, abordando: coloração aparente da água, odor, presença de lixo, materiais flutuantes, espuma e óleos, presença de vegetação, uso por animais, uso antrópico, proteção, identificação, proximidade com a residência e tipo de inserção da nascente. A pontuação variou entre 1 a 3 para cada aspecto, com intervalo cinco intervalo de classes para a configuração de nascente: ótima, boa, razoável, ruim e péssima. Foram analisadas seis nascentes, três no município de Campo Mourão e três em Luiziana, onde quatro nascentes apresentaram-se como ótimas e duas como boas.
EFFECT OF TEPID SPONGE ON CHANGES IN BODY TEMPERATUR IN CHILDREN
Authors: Puspitasari R.A. Helda , Handayani Dwining , Nastiti Ayu Dewi , Kusuma Erik
Published: December 2022

Introduction: Fever is a state of body temperature above normal as a result of an increase in temperature control in the hypothalamus. Most children have fever due to thermoregulation in the hypothalamus. The purpose of literature review is to explore the effect of giving a water tepid sponge on reducing fever in children.
Method: This study uses the literature review with article searches conducted on the electronic databases of Science Direct, Garuda and Google Schoolar. There were 543 articles on Science Direct, Garuda and Google Schoolar but only 10 articles that met all the inclusion criteria and were reviewed
Results: There is an effect on reducing fever in children by using a water tepid sponge.
Conclusion: Based on the results of a review of 10 literatures on reviewedthe characteristics of study respondents aged 1-12 years. Respondents who experienced hyperthermia/increased body temperature there was an influence of changes/decreased body temperature by giving water tepid sponge an averagerepeatedly so that the body temperature becomes 100% normal. The average temperature of children with fever in the 10 literatures is 38.5°C, the result with p value = 0.001 on the tepid water sponge which means that there is an effect of decreasing body temperature with the action of the water tepid sponge.
Assessing the Neurotoxicological Effect of the Acute Paraquat Aerosols Exposure in Causing Parkinsonism on Mouse through Behavioral Assays
Authors: Maulana Sherlo , Kamilah Santi Nurul , Muslim Choirul , Ruyani Aceng , Astuti R. R. Sri
Published: December 2022

Background: In the scientific community, there is no consensus that paraquat, a widely used herbicide, has a strong relationship with the occurrence of Parkinson’s disease. A reliable epidemiological explanation of how paraquat can induce parkinsonism is urgently needed because it relates to the agriculture community's potential public health problem. Objective: In this study, mice exposed to aerosols of paraquat solution were assessed by behavioral assays designed to observe whether mice exposed to paraquat aerosols develop cardinal symptoms of Parkinson’s disease, such as tremor-at-rest, bradykinesia, rigidity, and postural instability. Methods: To obtain the intended information, we carried out the observation on distal extremities, catalepsy test, wire suspension test, and swimming test consisting of the head position sub-test, the involvement of limbs sub-test, and the swimming direction test, respectively, to both the group of mice exposed to paraquat aerosols and the one which is not. Results: According to the result of the independent-samples t-test calculation on the data obtained from behavioral assays, a significant difference is shown only by the wire suspension test used to assess the development of forelimb rigidity and not the others. Conclusion: Therefore, this study showed that daily exposure for a week to paraquat aerosols insignificantly causes tremor-at-rest, bradykinesia, and postural instability in studied mice but dramatically affects their forelimb performance in the form of rigidity.
Online gaming and smartphone addictions in children and adolescents with primary headaches: A prospective case-control study
Authors: YILMAZ Arzu , GÖKER Zeynep , AYDIN GÖRÜCÜ Rezzan , TAŞAR Serçin
Published: December 2022

Aim: There is a few studies examining primary headaches and online gaming or smartphone addiction in line with causality.

Material and Method: Children and adolescents, aged 11-18 years old, those diagnosed with primary headaches of tension-type headache or migrain were evaluated in terms of smartphone and online game addiction. Smartphone Addiction Scale-Short Version (SAS-SV) and Online Game Addiction Scale (OGAS) was used. SPSS 17.0 program was used for statistical analyses.

Results: Children and adolescents with or without primary headaches had similar online game and smart phone usage pattern.

Conclusion: There is a need for further studies regarding primary headaches and its underlying factors in terms of online gaming or smart phone usage.
SPACED VOCABULARY ACQUISITION WHILE INCIDENTAL LISTENING BY ESL UNIVERSITY STUDENTS
Authors: Zubenko Tetiana , Gavrylenko Anastasiia , Zhyvotovska Tetyana , Vasylieva Nadiia
Published: December 2022

Based on a prior study by Zubenko and Shwedel (2019), the present study investigated the possible effects of repetition (repeated exposure) on the incidental acquisition and retention of 120 English target words by 51 Ukrainian-speaking ESL learners at a Ukrainian university. The hypothesis was that regular repetition of vocabulary while incidental listening would have a significant and positive effect on students’ vocabulary acquisition and performance. The paper examines the results of the implementation of spaced repetition of L2 vocabulary strategy of the second-year students who were covering the same vocabulary they learned during the experiment in the previous year. 7 audio lessons were created for increasing the long-term retention of target vocabulary in the students’ memory. Participants (N=51) were second-year Ukrainian university students majoring in English as a second language (ESL) at the age of 17-19. They were assigned to three groups, one experimental and two comparison. The optimal result based on the interval of repetitions influences the vocabulary recall and retention. Students who used the spaced L2 vocabulary acquisition strategy (SVAS) outperformed on the End-of-Experiment test 84,1 versus 80,6 for the Comparison group. The results prove that spaced L2 vocabulary acquisition strategy is an efficient part of enriching new vocabulary. The findings indicate that implications of this research are connected with the spaced vocabulary acquisition strategy as an effective tool for learning new lexical units by ESL learners while incidental listening to the audio dictionary lessons. Thus, the study results open up new possibilities for the teachers and learners to consider implementing audio dictionaries and similar tools as assets for efficient vocabulary learning.