bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN ANTARA PENGETAHUAN DAN POLA ASUH DENGAN STATUS GIZI BALITA DI POSYANDU DESA SUNGAI KAKAP TAHUN 2022
Authors: Vivi Rizki Alexander,
Published: November 2022

Usia balita merupakan masa terjadinya proses pertumbuhan yang sangat cepat sehingga pemenuhan gizi harus dimulai sedini mungkin. Di Posyandu Puskesmas Kakap dari 10 orang ibu yang diwawancarai hanya 4 orang ibu yang mengetahui tentang status gizi serta bentuk pola asuh pada Balita. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dan pola asuh ibu dengan status gizi balita di posyandu desa sungai kakap diWilayah Kerja Puskesmas Sungai Kakap Tahun 2022.  Penelitian ini menggunakan metode Deskriptif Korelasi dengan pendekatan cross sectional. dengan jumlah sampel 50 orang. Hasil penelitian analisis uji chi square tidak ada hubungan antara pengetahuan dengan status gizi Balita (p value 0,0713>0,05) dan tidak ada hubungan antara pola asuh dengan status gizi balita (p value ). Perlu melakukan komunikasi informasi dan edukasi (KIE) untuk keluarga, mengadakan demonstrasi tentang pola asuh yang baik dan benar serta pentingnya selalu memantau stayus gizi pada Balita.

Kata kunci: Pengetahuan, Pola Asuh, Status Gizi Posyandu
HUBUNGAN PENGETAHUAN DENGAN KEPATUHAN IBU HAMIL DALAM MELAKUKAN VAKSINASI COVID-19 DI PUSKESMAS PAL TIGA TAHUN 2022
Authors: Yuliani Elise Putri,
Published: November 2022

Covid-19 adalah penyakit yang disebabkan oleh virus. virus ini mucul pertama kali di provinsi Wuhan, Berdasarkan data terakhir Kementrian Kesehatan tercatat 2.179 ibu hamil yang terpapar covid-19 dan 18% di antaranya menyebabkan kematian. Hasil studi pendahuluan yang dilakukan pada 8 ibu hamil 4 orang ibu hamil mengatakan belum melakukan vaksinasi dengan alasan takut dan merasa khawatir untuk kesehatan dirinya dan janinnya dan mereka mau divaksinasi setelah melahirkan sedangkan 4 orang ibu hamil sudah divaksinasi dengan alasan bahwa vaksinasi covid-19 dapat meningkatkan kekebalan tubuh dan melindungi diri dari terpapar virus dimasa kehamilan. Tujuan penelitian untuk mengetahui hubungan antara pengetahuan dengan kepatuhan ibu hamil dalam melakukan vaksinasi COVID-19 di Puskesmas Pal Tiga tahun 2022. Jenis penelitian ini kuantitatif dengan deskritif kolerasi. Dilakukan dengan pendekatan cross sectional. Populasi 350 orang dan sampel 35 orang diuji Chi square. Sebagian dari responden yaitu 20 orang (57,1%) berpengetahuan baik tentang vaksiansi COVID-19 dan sangat sedikit dari responden yaitu 6 responden (17,1%) berpengetahuan kurang. Sebagian dari responden yaitu 18 responden (51,4%) tidak patuh sebagian dari responden yaitu 17 responden (48,6%) patuh. Hasil analisis bivariat dari 35 responden yang berpengetahuan baik dengan patuh melakukan vaksinasi yaitu 9 responden (45,0%) dan tidak patuh melakukan vaksinasi yaitu 11 responden (55,0%), responden yang berpengetahuan cukup dengan patuh melakukan vaksinasi 5 responden (55,6%) dan tidak patuh 4 responden (44,4%), responden berpengetahuan kurang dengan patuh melakukan vaksinasi yaitu 3 responden (50,0%) dan tidak patuh 3 responden (50,0%). Hasil analisis Chi Square X2=0,868 <0,05 maka ho di terima yang menyatakan bahwa tidak ada hubungan antara pengetahuan dengan kepatuhan dalam melakukan vaksinasi COVID-19. Tidak ada hubungan antara pengetahuan dengan kepatuhan menerima vaksinasi COVID-19 di puskesmas pal tiga tahun 2022. Diharapkan petugas kesehatan agar dapat memberikan informasi mengenai tentang vaksinasi COVID-19 pada ibu hamil untuk dapat melakukan vaksinasi COVID-19 sebagai upaya pencegahan meningkatnya angka kematian ibu akibat komplikasi penyakit yang disebabkan oleh Virus SARS-Cov.

Kata kunci: Pengetahuan, Kepatuhan, Ibu Hamil, Vaksinasi Covid-19, Puskesmas Pal Tiga
DETERMINAN KEJADIAN BERAT BAYI LAHIR RENDAH DI RUMAH SAKIT DAERAH DOKTER SOEDARSO PONTIANAK PERIODE TAHUN 2021 (DATA REKAM MEDIK)
Authors: Harson Tinambunan Windiyati,
Published: November 2022

Berat Bayi Lahir Rendah adalah bayi yang lahir dengan berat badan kurang dari 2.500 gram tanpa memandang masa kehamilan. Penyebab kematian neonatal diperkirakan Prematur (28%), infeksi berat (26%) dan asfiksia (23%), sedangkan tetanus neonaturum mempunyai proporsi yang kecil (7%) (Lawn, Cousens and Zupan, 2005). WHO menyebutkan, dari kematian periode normal 70% terjadi pada bayi BBLR. Tujuan dari Penelitian ini untuk mengetahui determinan Faktor yang Berhubungan dengan Kejadian BBLR yang mengalami BBLR dan yang tidak mengalami BBLR pada periode 2021. Desain yang digunakan dalam penelitian ini adalah Case Control, yaitu suatu penelitian atau Survey analitik yang menyangkut Faktor Resiko dengan menggunakan pendekatan Retrospective. Hasil dari penelitian yang menunjukan jumlah terbesar dari kasus : kontrol adalah pada usia kehamilan ini dinyatakan dengan taraf signifikan 5% (0,05) di dapatkan P Value α Sebagian responden kasus  ibu dengan usia  20 - 35 tahun sebanyak (53,1%), paritas <2 dan >4 anak sebanyak (50,0%), ekonomi menengah sebanyak (50,0%). Faktor yang secara statistik memiliki hubungan bermakna dengan kejadian BBLR di RSUD Dr.Sudarso pada tahun 2021 adalah : Usia ibu,usia kehamilan,Pendidikan dan penyakit yang menyertai. Dan Faktor risiko yang secara statistik memiliki hubungan tidak bermakna dengan kejadian BBLR di RSUD Dr.Sudarso pada tahun 2021 adalah ekonomi,paritas dan indikasi. Faktor risiko yang paling berpengaruh terhadap kejadian BBLR di RSUD Dr.Sudarso pada tahun 2021 adalah Usia kehamilan. Saran diajukan kepada tenaga kesehatan untuk dapat memberikan dan meningkatkan pelayanan kesehatan yang sebaik-baiknya terutama pada maternal yang mempunyai komplikasi pada ibu yag mempunyai resiko tinggi dengan kehamilannya agar angka kematian bayi khususnya BBLR dapat dihindari.
FAKTOR YANG BERHUBUNGAN DENGAN PEMILIHAN TEMPAT PERSALINAN PADA MASA PANDEMI COVID-19 DI PUSKESMAS RASAU JAYA TAHUN 2022
Authors: Elia Yuliana,
Published: November 2022

Pandemi Covid-19 dilaporkan berdampak pada penurunan cakupan K4 dari 88,54% (2020) menjadi 84,6% (tahun 2019) karena terhambatnya pelayanan ANC di daerah seperti halnya di Puskesmas Rasau Jaya sehingga mempengaruhi ibu hamil dalam pemilihan tempat persalinan yang sesuai dengan kebijakan Pemerintah. Hasil studi pendahuluan didapatkan 5 ibu hamil memilih bersalin di Polindes hal ini bertentangan dengan Permenkes No 21 tahun 2021. Tujuan penelitian ini untuk mengetahui “ Faktor yang Berhubungan dengan  Pemilihan Tempat Persalinan pada Masa Pandemi Covid-19 di Puskesmas Rasau Jaya tahun 2022. Metode Penelitian deskriptif korelatif dan pendekatan cross secational. Populasi ibu hamil trimester III berjumlah 60 orang dan sampel dalam penelitian ini berjumlah 54 orang analisis bivariat dengan chi square. Hasil penelitian didapatkan sebanyak 41 orang ibu hamil (76%) memilih bersalin di Puskesmas/ Praktik Mandiri Bidan, 25 orang (46%) berpengetahuan baik, 23 orang (43%) memperoleh informasi dari kerabat, 26 orang (48%) berpendidikan menengah dan 47 orang (87%) berumur 20-35 tahun. Hasil uji Statistik ditemukan ada hubungan antara variabel pengetahuan (p 0,027), sumber informasi (p 0,025), pendidikan (p value 0,004) dengan tempat bersalin. Sedangkan variabel umur ibu tidak berhubungan secara statistik (p value 0,889). Kesimpulan ada hubungan antara pengetahuan, sumber informasi dan pendidikan dengan pemilihan tempat bersalin sesuai kebijakan pemerintah pada masa Pandemi Covid 19. Disarankan bagi  bidan  untuk mengsosialisasikan tempat persalinan kepada ibu hamil yang sesuai dengan PP No 21 tahun 2021 menggunakan media penyuluhan yang lebih menarik seperti video edukasi dan dishare melalui media sosial.  .
HUBUNGAN ANTARA PENGETAHUAN IBU HAMIL TRIMESTER III DENGAN SIKAP DALAM PERSIAPAN PERSALINAN PADA MASA PANDEMI COVID-19 DI RB MULIA TAHUN 2022
Authors: Elise Putri, Katarina Iit, Natasya Tanjaya Megalina Limoy,
Published: November 2022

Menurut World Health Organization lebih dari 65 negara terinfeksi virus Covid-19. Data tangal 2 Maret 2020 tercatat 90.308 orang terkena Covid-19 dengan angka kematian 3.087 orang atau 2,3%. Berdasarkan studi pendahuluan, dari 10 orang ibu hamil trimester III yang dilakukan wawancara, terdapat 6 ibu hamil trimester III (60%) tidak mengetahui pengertian Covid-19 dan 4 ibu hamil trimester III (40%) mengetahui pengertian Covid-19. Tujuan penelitian : untuk menganalisis hubungan antara pengetahuan ibu hamil trimester III dengan sikap dalam persiapan persalinan di masa pandemi Covid-19 di RB Mulia Tahun 2022. Metode penelitian ini menggunakan analitik korelasi dengan pendekatan Cross sectional. Populasi dalam penelitian ini  sebanyak 156 orang  ibu hamil trimester III RB Mulia Tahun 2022 bulan Agustus 2022. Sampel dalam sampel sebanyak 59 responden, dengan teknik pengambilan sampel i menggunakan  purposive sampling.   Hasil penelitian sebagian besar dari responden yaitu 59 responden (53%) memiliki pengetahuan baik, sedangkan sikap ibu hamil trimester III diketahui bahwa sebagian dari responden yaitu 67 responden (60%) memiliki sikap mendukung. Maka hasil penelitian ini menunjukkan adanya hubungan antara pengetahuan ibu hamil trimester III dengan sikap dalam persiapan persalinan dimasa pandemi covid-19 dilihat dari p=0,000 < α=0,05, maka hubungannya signifikan. Berdasarkan hasil  penelitian yaitu pengetahuan ibu sebagian besar baik yaitu sebanyak 59 responden (53%) dan memiliki sikap mendukung terhadap persiapan persalinan pada masa pandemi Covid-19 yaitu sebanyak 67 responden (60%). Saran : diharapkan tenaga kesehatan harus meningkatkan peran untuk memberi informasi mengenai pengetahuan dan sikap ibu hamil trimester III dalam persiapan persalinan dimasa pandemi covid-19.
A 3D-Printed Ultrasound Task Trainer for the Practice of Hip Joint Injections
Authors: Chambers Mary E. , Day Alvin Lee , Resuehr David
Published: November 2022

Ultrasonography is often the preferred method of imaging for needle-guided procedures of the hip joint, including aspirations, local anaesthetic injections, and the use of corticosteroids. Phantoms (i.e., training devices mimicking human tissue and bony structures under acoustic sonography) are used to help train medical professionals to perform these procedures accurately, emphasising the art of physical simulation in unison with didactic learning. In the authors’ study, 3D printing technology was used to simulate an anatomically accurate human hip joint, with the hopes of creating an affordable and customisable ultrasound hip trainer, allowing novice sonographers to practice guided injections to hone their skills before performing these procedures on human subjects.
António da Costa Paiva (Barão de Castelo de Paiva) (1806–1879): his malacological collection from Madeira in Universidade de Coimbra, Portugal
Authors: Breves André , Pereira Gilberto , Girão Da Cruz M. Teresa
Published: November 2022

The Museu da Ciência da Universidade de Coimbra (MCUC) (Science Museum of the University of Coimbra) hosts an important historical collection of land and freshwater snails from the Madeira Archipelago. This collection of 1,768 specimens (120 recent taxa within 20 families) was recently catalogued and digitized. Specimens in MCUC collections were recognized as being provided by António da Costa Paiva (Barão de Castelo de Paiva). This Portuguese nobleman also donated other mollusc collections to different scientific institutions and natural history museums in Portugal and abroad in the mid nineteenth-century. The study of the origin of the MCUC mollusc collection, beyond the data associated with the specimens, is important to the research on the endangered fauna of the Madeira Archipelago. This work precedes a comprehensive study ongoing in MCUC regarding the species occurrence and the systematic review on a great number of species hosted in the museum collection.
Allan Octavian Hume (1829–1912): his development as an ornithologist until his departure from Etawah district, India, in 1867
Authors: Prŷs-Jones Robert P.
Published: November 2022

The ornithological studies of Allan Octavian Hume (1829–1912), and the enormous bird collection he amassed, have been of exceptional importance to the development of knowledge of the south Asian avifauna. However, the paucity of his surviving personal correspondence and private papers has made it difficult to trace the development of his own ornithological interest. Nine field diaries of Hume’s are held by the Natural History Museum, London. This paper draws on the first three of these, each covering periods of from one to a few months between late 1859 and late 1866, in combination with information from Hume’s bird collection, also now largely held by the Natural History Museum. Together they shed light on the evolution of his ornithological knowledge and interest during his career in India up to the time of his departure from Etawah district, North-Western Provinces, where he had been Officiating Magistrate and Collector for eleven years from early 1856 to early 1867.
Dalla comprensione del testo alla risoluzione del problema: un’esperienza nella scuola secondaria di secondo grado
Authors: Dello Iacono Umberto , Ferrara Dentice Eva , Mannillo Chiara Vitina , Vitale Maria Letizia
Published: November 2022

La risoluzione dei problemi è un’attività che crea difficoltà a molti studenti, indipendentemente dall’ordine scolastico, spesso legate alla fase di comprensione del testo del problema stesso. A tal proposito, abbiamo disegnato un’attività di apprendimento che prevede che gli studenti, a partire da alcuni problemi assegnati, individualmente e poi in maniera collaborativa, ne analizzino dapprima criticamente il testo per poi affrontarne la risoluzione. Abbiamo sperimentato tale attività con studenti del primo anno di una scuola secondaria di secondo grado. L’analisi dei dati mostra che l’attività didattica progettata sembra essere efficace nel favorire l’attivazione di adeguati processi risolutivi da parte degli studenti, nonché la produzione di argomenti a sostegno delle risposte fornite. In particolare, la maggior parte degli studenti, dopo aver lavorato sulla comprensione del testo, migliora la correttezza delle risposte e/o produce argomenti a supporto delle stesse.
Relazione etica degli studenti con un documento tratto dalla storia della matematica
Authors: Demattè Adriano
Published: November 2022

Un’attività di interpretazione di un brano tratto da Introductio in analysin infinitorum di Eulero, in una classe quinta della scuola secondaria di secondo grado, consente di evidenziare varie problematiche riguardanti una relazione di responsività e responsabilità – che in questo articolo viene denominata etica – da parte degli studenti con un testo matematico e in particolare con un documento storico. L’analisi viene operata alla luce del pensiero dei filosofi Emmanuel Levinas e Hans-Georg Gadamer. L’attenzione è rivolta a come gli studenti orientino la loro interpretazione, come affrontino la situazione di alterità – di confronto con il punto di vista dell’Altro – e come seguano l’autore nei suoi ragionamenti.
THE IMPACT OF THE COVID-19 PANDEMIC ON THE MANAGEMENT OF THE SUMATRAN TIGER (panthera tigris sumatrae pocock) IN CONSERVATION INSTITUTIONS FOR THE PUBLIC INTEREST (CASE STUDY AT TAMAN SAFARI INDONESIA CISARUA BOGOR AND RAGUNAN WILDLIFE PARK JAKARTA)
Authors: Herdiana Herdiana , Rahayu Sata Yoshida Srie , Retnowati Rita
Published: November 2022

The World Health Organization (WHO) as a world health institution declared COVID-19 as a global pandemic on March 11, 2020 and Indonesia officially announced a confirmed case of COVID-19 infection on March 2, 2020. One of the tourist attractions affected by COVID-19 is the Conservation in the Public Interest such as safari parks, zoos and animal parks. This study aims to: analyze the management of the Sumatran Tiger in the Indonesian Safari Park Cisarua Bogor and the Ragunan Wildlife Park during the COVID-19 pandemic, analyze the steps to minimize the impact of the COVID-19 pandemic on the management of the Sumatran Tiger at the Indonesian Safari Park Cisarua Bogor and the Ragunan Wildlife Park. as well as formulating a strategy for managing the Sumatran Tiger in the face of a disease pandemic at the Taman Safari Indonesia Cisarua Bogor and the Ragunan Wildlife Park. The research method used is descriptive research method. The source of research data comes from primary data sources, namely the management of the Indonesian Safari Park Conservation Agency Cisarua Bogor and Ragunan Wildlife Park and secondary data sources obtained from literature studies. The data taken are the management of Sumatran tigers at the Cisarua Bogor Indonesian Safari Park and Ragunan Wildlife Park and the types of use of the Sumatran tiger in the Cisarua Bogor Indonesian Safari Park and Ragunan Wildlife Park. Field observations were carried out to photograph and directly collect data on the condition of the Indonesian Safari Park Conservation Institute, Cisarua Bogor and Ragunan Wildlife Park, as well as the management of the Sumatran Tiger which includes aspects of management, manpower handling animals, and utilization and documentation studies. Processing of data from observations, interviews and documentation studies using descriptive qualitative analysis, and SWOT analysis. Based on the results of the study, that the operational management of the Sumatran Tiger at Taman Safari Indonesia Cisarua Bogor and the Ragunan Wildlife Park runs in accordance with the rules of animal management applied at the General Conservation Institute even though the COVID-19 pandemic has affected the income generated from visitor entrance tickets, especially for the park. Safari Indonesia Cisarua Bogor. The implication of this research is to minimize the impact of the COVID-19 pandemic on the operational management and protection of Sumatran tigers in the General Conservation Institute, the government together with the Indonesian Zoo Association and the managers of the General Conservation Institute need to immediately draw up an emergency plan for animal management, especially the Sumatran tiger, while maintaining based on aspects of animal welfare and compiling Standard Operating Procedures to prevent the spread of COVID-19.
ASSOCIATIVE ANALYSIS BETWEEN BEHAVIOR AND CONSERVATION KNOWLEDGE WITH CLIMBER’S PERCEPTIONS OF EDELWEISS (anaphalis javanica) ABUNDANCE IN GUNUNG GEDE PANGRANGO NATIONAL PARK
Authors: Hasbilah Asep , Istiadi Yossa , Rahayu Sata Yoshida Srie
Published: November 2022

Edelweiss in Gunung Gede Pangrango National Park (GGPNP) is one of the flora that has its attraction in supporting natural climbing tourism activities. The existence of this climbing activity with various types of climbing goals, climber behavior, limited knowledge in conservation, and so on will provide opportunities for threats to the edelweiss biodiversity. The purpose of research are to know the relationship between climber’s behavior with perceptions of Edelweiss abundance, the relationship between conservation knowledge with perceptions of Edelweiss abundance, and the relationship togethereness climber’s behavior, and conservation knowledge with perceptions of Edelweiss abundance (Anaphalis javanica) in, GGPNP. The method of collecting data to obtain primary data in the field is a non-test technique (questionnaire) in the form of a questionnaire composed of several statements relating to each variable and indicators of research variables. Hypothesis test is used the regression and correlation analysis. The results showed that there was a positive and significant relationship between climber behavior (X1) and perceptions of Edelweiss abundance in GGPNP (Y) with a correlation coefficient (r) = 0.948. This relationship can be made by the equation = 47.809+0.338 X1. There is a positive and significant relationship between conservation knowledge (X2) and perceptions of edelweiss abundance (Y) with a correlation coefficient (r) = 0.957. This relationship can be made by the equation = 47.809 + 1.316 X2. There is a positive and significant relationship between climber behavior (X1) and conservation knowledge (X2) together with the perception of edelweiss abundance (Y) with a correlation coefficient (r) = 0.966. The relationship can be made the equation = 47.809 + 0.338X1 + 1.316X2. Implications that can be carried out as a follow-up to the results of this study include the need for continuous efforts to improve conservation behavior and knowledge of climbers, especially those who climb Mount Gede Pangrango.
THE EXISTENCE OF ALBASIA PLANTS IN CIKARAMAS VILLAGE: A CASE STUDY OF ALBASIA CULTIVATION IN CIKARAMAS VILLAGE, SUMEDANG REGENCY, WEST JAVA
Authors: Khairuzani Hamda
Published: November 2022

With forestry development, it is hoped that national development goals will be achieved, in particular the improvement of living standards and community welfare accompanied by improvement of their living environment. Wood is one of the main forest products, which is needed by the community to meet various needs of human life. Although nowadays there are many synthetic materials that can substitute the use of wood, the demand for wood for various purposes is still quite high and even shows an increasing demand. The benefits of this wood are growing, starting from the need for wood for energy, building materials, wood pulp, furniture, to the use of wood for aircraft fuselages. The planting of sengon trees by the community in Cikaramas Village is quite developed and is very suitable considering the topography and land conditions that are suitable for the place where sengon trees grow. Then it becomes a separate added value, if farmers/communities are able to optimize inputs for forest plant cultivation by knowing in advance the characteristics/characteristics of the soil. Albasia that developed in Cikaramas Village, is part of the knowledge system of Cikaramas Village residents about timber plants. The system is a legacy of knowledge about the types and uses of woody plants for subsistence needs used for building materials. Prior to the development of albasia, wood plants of the type of tissue, jackfruit wood, and the type of "swamp" wood had been developed and used for the needs of previous building materials. Then the development of albasia plant species, causing choices in developing woody plants to be utilized and to be developed in more intercropping systems. This allows farmers to choose based on their knowledge and experience, and choose based on the benefits and advantages derived from the timber plant, which will be developed in an intercropping system. This study uses descriptive qualitative research, researchers try to get a picture of the ongoing state of the object of research according to the actual situation, so that accurate data can be obtained with an actual picture from the analysis of the observed phenomena. Through this research, it is hoped that data will be obtained and presented through the use of words to obtain a more concrete, detailed and accurate description of certain phenomena.  The development and use of Albasia in Cikaramas Village is a form of adaptation carried out by the community that responds to environmental suitability and changes. Response to information or ideas that enter the social system of Cikaramas Village, which has an influence on the ecological system of Cikaramas Village. And the socio-economic activities of Albasia gave birth to the Albasia trading network. As well as the survival of Albizia as a commodity crop under the influence of the threat of crop failure due to pests, factored in by economic sector and ecological sector.
SPATIAL ANALYSIS OF ENVIRONMENTAL SENSITIVITY FOR MITIGATION OF OIL SPILL DISASTERS IN THE SERIBU ISLANDS NATIONAL PARK
Authors: Khabibi Rokhmad , Rosadi Rosadi , Rahayu Sata Yoshida Srie
Published: November 2022

The Seribu Islands National Park (Taman Nasional Kepulauan Seribu - TNKpS) which has a marine ecosystem area that has the potential to be affected by oil spills originating from oil discharges from ships passing through the Sunda Strait and ship accidents in and out of Tanjung Priuk Port. In addition, in the TNKpS area there are also oil and gas mining companies as well as oil distribution through pipelines which have the potential to cause oil pollution due to leakage of oil distribution pipelines. The availability of maps of Environmental Sensitivity Index and comprehensive environmental data is important for the government to understand the condition of sensitive areas around oil and gas mining areas to mitigate environmental pollution due to oil spills, and can then take priority actions. to protect areas deemed sensitive. The compilation of thematic maps related to environmental sensitivity to oil spills in TNKpS shows that the beach type is not sensitive to oil spills, where the dominant beach type is gently sloping sand which is a substrate that is easy to clean when an oil spill occurs. While the component of biodiversity has the highest sensitivity. The most sensitive socioeconomic components affected by the oil spill are fish farming and marine tourism (snorkeling and diving), both of which are the main livelihoods for the people in TNKpS, especially from the tourism sector. Mitigation of oil spills in TNKpS should focus on dealing with oil spills before reaching sensitive areas where oil collection with skimmers and spraying of dispersants can be carried out before entering the coral reef area. The next step is the protection of sensitive areas from oil spills where this protection can be done by dispelling using an oil boom and directing the oil spill to a less sensitive area. The final step is cleaning the beach area in accordance with oil spill emergency response procedures. Spill simulations carried out with a duration of 3 hours, 5 hours and 24 hours showed that the oil spill had not yet reached the sensitive area when it was 3 hours, so that the ideal anticipatory oil response is to have an oil control exercise with a duration of 3 hours to protect sensitive areas.
Evaluation of the breeding practices and population trend of the Fogera cattle breed in Ethiopia
Authors: Tesfa Assemu , Bimerew Tewodross , Tilahune Mekonnen , Kassahun Demelash , Kebede Adebabaye , Mengesha Wondimagegn
Published: November 2022

The study was conducted to estimate the population size, herd structure, and breeding objectives of Fogera cattle in Ethiopia. It was carried out in 23 purposively selected kebeles in five districts of three zones bordering Lake Tana. Interviewed farmers were selected based on their livestock ownership. Primary information on the general production system and trends of Fogera cattle was collected from 527 farmers, and a population count included 479 respondents. To differentiate the pure Fogera cattle from the mixed and highland zebu breeds, color photographs of the three breeds were used by each enumerator. Kebele administrators and elders as well as district and zone officials assisted in the operation to identify the true type of Fogera cattle. MS-Excel (2010) and SPSS (version 20) were used to analyze population size and production systems, respectively. The average cattle holding per household was 7.03 ± 0.2 heads. Analysis of multiple responses revealed that the dominant reasons for keeping cattle in the herd were traction power (96.67%), milk (92.76%), and manure (83.95%). More than half of the respondents (64.65%) practiced culling both male and female animals from their herds. Interviewed farmers selected bulls for mating by coat color (56.84%), body conformation (55.08%), and body size (47.46%). They also indicated that they selected the Fogera breed (48.63%), highland zebu (18.16%), and mixed (17.38%) as bulls for mating with their cattle. Based on the respondents’ information, the population trend of the Fogera breed decreases (40%), increases (13%), is stable (6%), and is not known (41%). From the total population estimated, households own the relatively pure Fogera (41%), Fogera–zebu mix (35%), and highland zebu (24%). In this study, the total estimated number of breeding Fogera cattle was 55,646 ± 16,579 heads. It was concluded that the breed has declined and is dealing with genetic deterioration as the population size decreases due to the shift of grazing lands to crop production. As population estimation was performed by morphological features, further research supported by molecular study should be conducted.
Inhibition of cellulase activity by liquid hydrolysates from hydrothermally pretreated soybean straw
Authors: Kim Daehwan , Ji Anqi , Jackson Armoni L. , Brown Bailee , Kim Youngmi , Kim Sun Min , Laufer Craig , Ferrier Drew , Yoo Chang Geun
Published: November 2022

The one-pot biomass conversion process is a promising strategy to minimize potential product loss and reduce processing costs. However, this strategy has technical limitations due to the inhibitory effects of biomass components like lignin as well as the generated inhibitors (e.g., furans, phenols) during biomass processing. In this study, the inhibitory effects of liquid hydrolysates formed by hydrothermal pretreatment of soybean straw with either sodium hydroxide (NaOH) or hydrogen peroxide (H2O2) on cellulolytic enzyme activity were investigated. Hydrothermal pretreatment of soybean straw (10% w/v) was carried out with either sodium hydroxide (1% v/v) or hydrogen peroxide (1% v/v) at 121°C for 60 min to evaluate the effect of water-soluble inhibitors released from soybean pretreatment on cellulolytic enzyme activity. The fraction of cellulose in pretreated solids (1% w/v glucan) was enzymatically hydrolyzed for 72 h with 45 IU/g glucan (corresponding to 25 mg enzyme protein/g glucan) in the presence of either buffer or liquid hydrolysate generated from the pretreatments. Hydrolysis of NaOH and H2O2 pretreated solids resulted in 57% and 39% of glucose yields in buffer, respectively. In the presence of the liquid hydrolysates, NaOH and H2O2 pretreated biomass showed 20% and 30% glucose yield, respectively, indicating the enzyme suppression by inhibitors in the liquid hydrolysates. Of the enzyme activities in hydrolysates tested, NaOH hydrolysate showed a higher inhibitory effect on enzyme activities (mainly β-glucosidase) compared to H2O2 liquid, where enzyme deactivation has a first-order correlation and the manner in which the vacuum-filtered inhibitors were generated from pretreated soybean straw.
Tuberculosis detection from raw sputum samples using Au-electroplated screen-printed electrodes as E-DNA sensor
Authors: Sharif M. N. , Taufiq S. , Sohail M. , Abbas S. R.
Published: November 2022

Tuberculosis (TB) remains a leading cause of death globally, especially in underdeveloped nations. The main impediment to TB eradication is a lack of efficient diagnostic tools for disease diagnosis. In this work, label free and ultrasensitive electrochemical DNA biosensor for detecting Mycobacterium tuberculosis has been developed based on the electrodeposition of gold nanoparticles on the surface of carbon screen-printed carbon electrode (Zensors) for signal amplification. Particularly, screen-printed electrodes were modified by electrochemical deposition of Au to enhance the conductivity and facilitate the immobilization of ssDNA probes via Au-S bonds. The electrochemically modified SPEs were characterized using Scanning electron microscopy/Energy Dispersive X-Ray Analysis (SEM/EDX) and X-Ray Diffraction (XRD). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques were used to investigate the DNA hybridization between single-stranded (ssDNA) probe and target DNA (tDNA). Under the ideal conditions, DPV exhibited a correlation coefficient R2 = 0.97, when analyzed with different tDNA concentrations. The proposed DNA biosensor exhibits a good detection range from 2 to 10 nm with a low detection limit of 1.91 nm, as well as high selectivity that, under ideal conditions, distinguishes non-complementary DNA from perfectly matched tDNA. By eliminating the need for DNA purification, this work paves the path for creating disposable biosensors capable of detecting DNA from raw sputum samples.
Progress of CT aortic angiography combined with coronary artery in the evaluation of acute aortic syndrome
Authors: An Hengbin , Xie Ruigang , Ge Yinghui , Wang Tianyun
Published: November 2022

Acute aortic syndrome (AAS) is a group of cardiovascular diseases that seriously threaten human life and health. AAS patients are often complicated with coronary artery disease and other related diseases, which require rapid and clear clinical diagnosis to avoid serious adverse events. In recent years, with the progress of science and technology, a variety of computer tomography (CT) angiography techniques have been applied in the clinic, and the diagnosis rate of AAS with coronary heart disease (CAD) has greatly increased. At the same time, the development of surgical technology and endovascular repair technology has significantly reduced the mortality and complication rate of AAS surgery. In the clinical diagnosis of AAS and related diseases, CT aortic angiography (CTA) combined with coronary CTA is increasingly applied to identify related diseases. Here, the current research progress on the technique of aortic CTA combined with coronary CTA is reviewed.
Ventricular arrhythmias originating from the basal septum of the ventricle: Clinical and electrophysiological characteristics and a systematic ablation approach
Authors: Shi Linsheng , Wang Cheng , Chen Hongwu , Yang Gang , Gu Kai , Li Mingfang , Chu Ming , Liu Hailei , Wang Zidun , Ju Weizhu , Chen Minglong
Published: November 2022

Background

There is a paucity of data about VAs clustered at the vicinity of the basal septum of the ventricle. We aimed to report and characterize the clinical and electrophysiological features of basal septum VAs and explore the systematic ablation approach.

Methods

A consecutive series of 51 patients who had their VAs successfully ablated at the basal septum of the ventricle was enrolled in this study. The basal septum was defined as the area 2 cm away from the septal annulus, the upper boundary was the site of the left or right His-Purkinje system, and the lower boundary was the borderline that separated away from the septum. RFCA was performed based on detailed activation mapping or pace mapping. Patients who underwent VA ablation from other areas of the tricuspid annulus (TA) and mitral annulus (MA) during the same period were enrolled as the control group.

Results

The patients with basal septum VAs were significantly older (p < 0.01) and had more comorbidities (hypertension and coronary artery disease) (p < 0.01). Meanwhile, the precordial R wave transition was significantly different in right side, left side and intramural foci group (p < 0.001). Acute procedural success was achieved in 44 patients (86.3%) in the study group and in 63 patients (95.5%) in the control group. After a median of 12 (6–36) months of follow-up, compared with VA recurrence in the control group (2 cases), 11 patients with basal septum VAs had recurrences (p = 0.002), while a delayed cure was observed in 3 in intramural foci group.

Conclusion

Based on the unique anatomical and electrophysiological characteristics, a systematic approach for VAs originating from the basal septal area is warranted. Moreover, the follow-up data seemed to show a relative high recurrence rate for basal septal VAs during a period of time.
Mapping urban socioeconomic inequalities in developing countries through Facebook advertising data
Authors: Piaggesi Simone , Giurgola Serena , Karsai Márton , Mejova Yelena , Panisson André , Tizzoni Michele
Published: November 2022

Ending poverty in all its forms everywhere is the number one Sustainable Development Goal of the UN 2030 Agenda. To monitor the progress toward such an ambitious target, reliable, up-to-date and fine-grained measurements of socioeconomic indicators are necessary. When it comes to socioeconomic development, novel digital traces can provide a complementary data source to overcome the limits of traditional data collection methods, which are often not regularly updated and lack adequate spatial resolution. In this study, we collect publicly available and anonymous advertising audience estimates from Facebook to predict socioeconomic conditions of urban residents, at a fine spatial granularity, in four large urban areas: Atlanta (USA), Bogotá (Colombia), Santiago (Chile), and Casablanca (Morocco). We find that behavioral attributes inferred from the Facebook marketing platform can accurately map the socioeconomic status of residential areas within cities, and that predictive performance is comparable in both high and low-resource settings. Our work provides additional evidence of the value of social advertising media data to measure human development and it also shows the limitations in generalizing the use of these data to make predictions across countries.
Digital mental health interventions for chronic serious mental illness: Findings from a qualitative study on usability and scale-up of the Life Goals app for bipolar disorder
Authors: Rusch Amy , Carley Isabel , Badola Pratiksha , Liebrecht Celeste , McInnis Melvin , Ryan Kelly A. , Smith Shawna N.
Published: November 2022

The Life Goals (LG) application is an evidence-based self-management tool intended to help individuals with bipolar disorder (BD) by aligning symptom coping strategies with personal goals. The program has traditionally been offered in-person or via the web, but has recently been translated into an individualized, customizable mobile intervention to improve access to care and reduce provider burden. The LG app previously showed acceptability with ease of use and satisfaction with user interface, but less success in encouraging self-management. To better understand patient needs, our team conducted semi-structured interviews with 18 individuals with BD who used the LG app for 6 months. These interviews also investigated participant interest in sharing LG app data with their provider through an online dashboard. Using affinity mapping, a collaborative, qualitative data analysis technique, our team identified emerging common themes in the interviews. Through this process, team members identified 494 pieces of salient information from interviews that were mapped and translated into three main findings: (1) many participants found Mood Monitoring and LG modules helpful/interesting and stated the app overall had positive impacts on their mental health, (2) some components of the app were too rudimentary or impersonal to be beneficial, and (3) feedback was mixed regarding future implementation of an LG provider dashboard, with some participants seeing potential positive impacts and others hesitating due to perceived efficacy and privacy concerns. These findings can help researchers improve app-based interventions for individuals with BD by increasing app usage and improving care overall.
Factors associated with the progression of mesangial lesions in IgA nephropathy: A comparative analysis of renal re-biopsies
Authors: Li Yetong , Jiang Shimin , Gao Hongmei , Yang Yue , Liu Xiaorong , Li Wenge
Published: November 2022

Objectives

IgA nephropathy (IgAN) is the most common primary glomerular disease, and is the leading cause of chronic renal failure. Because mesangial lesions are the main pathological changes seen in IgAN, we investigated factors associated with the progression of mesangial lesions in IgAN.

Methods

We enrolled participants with IgAN who underwent repeat renal biopsies. Based on the progression of mesangial proliferative lesions, the participants were divided into progressive and stable groups. The progression group included participants with a ratio of mesangial cell proliferation score ≥ 1.1 (i.e., proliferation of > 10%) in the second biopsy specimen compared to the first biopsy specimen. The stable group included participants who did not fulfill the aforementioned criteria. We recorded the laboratory parameters, expression of renin-angiotensin system (RAS) receptors (angiotensin II type 1 receptor [AT1R], angiotensin II type 2 receptor [AT2R], Mas receptor [MasR], and the Mas-related G protein-coupled receptor, member D [MrgD]) and mesangial matrix proteins (collagen [Col] IV, fibronectin [FN] and laminin) at the first and second renal biopsies, and the use of immunosuppressive therapy and/or RAS blockers after the first biopsy.

Results

We enrolled 24 patients with IgAN who underwent repeat renal biopsies. Half of patients showed progression of mesangial lesions on repeat renal biopsy after a median of 4.3 (1–6) years. The progression group had significantly higher expression levels of AT1R and mesangial matrix proteins (Col IV and FN), and significantly lower expression of AT2R and MasR, compared to the stable group. Multivariate analysis showed that the use of RAS blockers (hazard ratio [HR], 0.27; 95% CI, 0.08–0.97; p < 0.05) and the level of proteinuria (HR, 1.8; 95% CI, 1.04–3.12; p < 0.05) were associated with progression of mesangial lesions. Additionally, the progression group exhibited a more rapid decline of renal function compared to the stable group (0.38 and 0.012 ml/min/1.73 m2/month, respectively; p = 0.004).

Conclusions

Continuous activation of the intrarenal RAS and massive proteinuria correlate with histological progression of mesangial lesions in IgAN patients, which may further accelerate the deterioration of renal function.
Clinical, genetic, and epidemiological survey of Polish children and adolescents with severe obesity: A study protocol of the Polish–German study project on severe early-onset obesity
Authors: Mierzwa Magdalena , Bik-Multanowski Mirosław , Ranke Michael B. , Brandt Stephanie , Flehmig Bertram , Małecka-Tendera Ewa , Mazur Artur , Petriczko Elżbieta , Wabitsch Martin , Wójcik Małgorzata , Zachurzok Agnieszka
Published: November 2022

Severe early-onset obesity (SEOO) in children is a common feature of monogenic obesity. Nowadays, mutations in at least 50 genes are known to be related to monogenic obesity, and many others are tested. Part of them is involved in the leptin–proopiomelanocortin pathway. The aim of the project is to establish the Polish database of severely obese children and adolescents and to evaluate the prevalence of monogenic forms of obesity in this cohort, with a special focus on leptin–proopiomelanocortin pathway abnormalities. The secondary project aim is to identify new population-specific mutations in obesity-related genes in severely obese Polish children and adolescents. This is a prospective multi-center clinical study performed in four Polish centers. The estimated sample size is 500 patients aged 1–18 years, with severe obesity, hyperphagia, and food-seeking behaviors. In each patient, the medical history regarding the obesity duration in the patient and obesity and its complication existence in the family will be taken. Next, the questionnaire regarding the symptom characteristic of specific mutations, which we are going to test, will be performed. Hyperphagia will be assessed on the basis of age-specific questionnaires. The physical examination with anthropometric measurement, basic biochemical and hormonal tests, and leptin and biologically active leptin measurements will be performed. Finally, genetic analysis will be performed using next-generation sequencing with sequencing libraries prepared to include obesity-related genes. The genotyping findings will be confirmed with the use of classic sequencing (Sanger’s method). In the future, the pathogenicity of new mutations in obesity-related genes identified in our cohort is planned to be confirmed by functional testing in vitro. Nowadays, there are no data regarding the prevalence of severe obesity or monogenic obesity in Polish children. This project has the potential to improve understanding of obesity etiology and may contribute to implementing attribute mutation-specific treatment. Moreover, it may lead to a finding of new, population-specific mutations related to SEOO.
Muscle endurance: Is bipedalism the cause?
Authors: D’Antona Giuseppe , Burtscher Martin
Published: November 2022

One may ask if the transition to bipedalism from the condition of quadrupedalism, which occurred about 7 million years ago, has been the cause or consequence of a series of fundamental physiological muscular aspects including the cost of locomotion, a crucial determinant of endurance, which has been found to be significantly lower in humans than in apes. This issue strictly links to unsolved issues regarding the significance of several muscular structural and functional adaptations, classically attributed to bipedalism and its associated locomotions, which we cannot simply attribute to the acquisition of the upright position and which may directly or indirectly contribute to the observed changes in muscle energetics that make the modern human an exceptional endurance walker and runner compared to quadrupedals.
Cross-continental collaboration for understanding postpartum major depression with psychotic features
Authors: Kimmel Mary , Thippeswamy Harish , Kamperman Astrid , Madhuri H. N. , Putnam Karen , Schiller Crystal , Weinel Katie , Rackers Hannah , Gilden Janneke , Bergink Veerle , Meltzer-Brody Samantha , Chandra Prabha
Published: November 2022

Purpose

Assess postpartum depression and psychotic symptoms from three continents.

Methods

Compare numbers of women with depression and psychotic symptoms, mania with or without psychotic features, or transient non-affective psychosis and medication choice.

Results

The prevalence of postpartum depression and psychosis and treatment choice differed at each site.

Conclusions

Best treatment for postpartum depression with psychotic features has not been established yet. Cross-continental collaboration with similar assessments holds promise to develop best practices for these high risk mother-infant dyads.
Russian honey bee genotype identification through enhanced marker panel set
Authors: Avalos Arian , Bilodeau Lelania
Published: November 2022

Russian honey bees (RHB) are a breeding population developed by USDA-ARS as an effort to provide Varroa-resistant honey bees to beekeepers. The selection strategy for this breeding population was the first in honey bees to incorporate genetic stock identification (GSI). The original GSI approach has been in use for over a decade, and though effective, novel technologies and analytical approaches recently developed provide an opportunity for improvement. Here we outline a novel genotyping assay that capitalizes on the markers used in the GSI as well as new loci recently identified in a whole genome pooled study of commercial honey bee stocks. Our approach utilizes a microfluidic platform and machine learning analyses to arrive at an accurate, high throughput assay. This novel approach provides an improved tool that can be readily incorporated into breeding decisions towards healthier more productive bees.
None detected: What “zero” indicates in direct counts of aquatic microorganisms in treated ballast water
Authors: First Matthew R. , Robbins-Wamsley Stephanie H. , Riley Scott C. , Grant Jonathan F. , Molina Vanessa , Wier Timothy P.
Published: November 2022

International limits on the concentrations of living organisms in ballast water are now in force for commercial ships. Microscopy-based, “direct count” assays estimate the concentrations of organisms. These assays are used in performance tests of Ballast Water Management Systems (BWMSs), which are shipboard technologies designed to reduce living organisms in ballast water to below the discharge limits. Here, we examine the factors that affect the method detection limit (MDL) of direct count assays. The MDL depends upon the volumes sampled, concentrated (or diluted), and analyzed, so the MDL will vary as these volumes vary from analysis-to-analysis. Decreasing the MDL to detect exceedingly rare individuals (e.g., ~1 individual per m3 or fewer) is possible, but problematic, given the challenges in analyzing dynamic communities of living organisms: increasing sample and analysis volumes to lower the MDL will likely accelerate the loss of individuals, as organisms are concentrated to several orders of magnitude above in situ concentrations and held for extended times. Results of direct count assays may be widely disseminated as an indicator of the performance of BWMSs, and when no organisms are detected, concentrations may be shown as “0 organisms per m3 or mL” rather than “<MDL”, as appropriate. When clearly derived and reported, a numerical MDL for the direct count assay—the lowermost value distinct from “zero”—provides context to results and transparency into the sensitivity of the assay.