bluuebunny/crossref_metadata_2025 huggingface dataset:
Anisotropic Gold Nanoparticle-Cell Interactions Mediated by Collagen
Authors: Marișca Oana T. , Leopold Nicolae
Published: April 2019

Gold nanoparticles (AuNPs) are the groundwork of a large variety of applications in the biomedical field. Further development and a better understanding of this versatile platform will lead to an expansion of potential applications. In this study, we propose a facile synthesis of AuNPs using hydrogen peroxide as a reducing agent and collagen as a stabilizing agent. Our synthetic approach results in “raspberry”-like AuNPs with a mean diameter of 60 nm, as revealed by electron microscopy. The optical properties of the AuNPs were assessed by UV-Vis and surface-enhanced Raman scattering (SERS), and their stability and in vitro cytotoxicity were evaluated as well. HeLa cell viability values were only modestly affected compared to control, with the highest concentration tested displaying a 20% decrease in cellular viability. The dose-dependent cellular internalization in the 20–60 nM range indicate the highest internalization rate at 60 nM and uptake values as high as 35%. This result correlated well with the viability results. These type of anisotropic AuNPs are proposed for biomedical applications such as hyperthermia, contrast agents or imaging. Therefore, our findings offer a platform for potential biological applications such as sensing and imaging, due to their unique physico-chemical features.
Influence of Polycarboxylate Superplasticizers with Different Functional Units on the Early Hydration of C3A-Gypsum
Authors: Hu Kuangyi , Sun Zhenping
Published: April 2019

Influence of polycarboxylate superplasticizers (PCs) with different functional units on the hydration heat and hydration products of C3A-gypsum was investigated. Three kinds of PCs with different monomers were discussed. It was seen that PCs mainly shortened the induction stage of C3A-gypsum hydration, and the amount of remaining gypsum was related to the duration of the induction stage. The second heat flow peak of the sample with PCs was higher than that of the blank. Moreover, PC intercalation occurred during the hydration.
Experimental Analysis and Simulation of Novel Technical Textile Reinforced Composite of Banana Fibre
Authors: Monzón Mario D. , Paz Rubén , Verdaguer Martí , Suárez Luis , Badalló Pere , Ortega Zaida , Diaz Noelia
Published: April 2019

The use of natural fibres allows reducing environmental impact, due to their natural renewable origin and the lower energy needed for their production and processing. This work presents the mechanical characterization of a newly developed technical textile, with banana fibre treated by enzymes, comparing experimental results with numerical simulation based on the definition of the unit cell at micromechanical level. The experimental test shows that the composite with the fabric of banana fibre presents worse mechanical behaviour than the one with commercial flax fibre. The presence of wool, necessary for producing the yarn, reduces the mechanical properties of the banana textile. The numerical simulation had an acceptable error compared with the experimental results, with a global average error of 9%, showing that the predictive modelling based on the multiscale method is suitable for the design process of this kind of composite.
Zintl Phases as Reactive Precursors for Synthesis of Novel Silicon and Germanium-Based Materials
Authors: Beekman Matt , Kauzlarich Susan M. , Doherty Luke , Nolas George S.
Published: April 2019

Recent experimental and theoretical work has demonstrated significant potential to tune the properties of silicon and germanium by adjusting the mesostructure, nanostructure, and/or crystalline structure of these group 14 elements. Despite the promise to achieve enhanced functionality with these already technologically important elements, a significant challenge lies in the identification of effective synthetic approaches that can access metastable silicon and germanium-based extended solids with a particular crystal structure or specific nano/meso-structured features. In this context, the class of intermetallic compounds known as Zintl phases has provided a platform for discovery of novel silicon and germanium-based materials. This review highlights some of the ways in which silicon and germanium-based Zintl phases have been utilized as precursors in innovative approaches to synthesize new crystalline modifications, nanoparticles, nanosheets, and mesostructured and nanoporous extended solids with properties that can be very different from the ground states of the elements.
An Apparatus for Spectral Emissivity Measurements of Thermal Control Materials at Low Temperatures
Authors: Ma Jiayu , Zhang Yuzhi , Wu Lingnan , Li Haogeng , Song Lixin
Published: April 2019

Thermal control materials are employed to adjust the temperature of a spacecraft operating in deep space. The spectral emissivity is a crucial factor in evaluating the thermal radiative properties of such materials. An apparatus, composed of a Fourier transform infrared spectrometer (FTIR), a sample cooling chamber and a mechanical modulation system was demonstrated to measure low temperature infrared spectral emissivity under vacuum. The mechanical modulation system, which includes a chopper and a lock-in amplifier, is employed to reduce the interference of background radiation during measurements. The limitation of the Fourier transform frequency on the chopper frequency can be eliminated by setting the FTIR on step-scan mode. The apparatus is separated into two parts and evacuated by different pumps. In this study, a high quality emission spectrum of a sample is measured by the apparatus. The spectral emissivity of thermal control materials are obtained in the wavelength range of 8 to 14 μm at 173 and 213 K. The combined standard uncertainty of the apparatus is 3.30% at 213 K.
Graphene Oxide Oxygen Content Affects Physical and Biological Properties of Scaffolds Based on Chitosan/Graphene Oxide Conjugates
Authors: Francolini Iolanda , Perugini Elena , Silvestro Ilaria , Lopreiato Mariangela , Scotto d’Abusco Anna , Valentini Federica , Placidi Ernesto , Arciprete Fabrizio , Martinelli Andrea , Piozzi Antonella
Published: April 2019

Tissue engineering is a highly interdisciplinary field of medicine aiming at regenerating damaged tissues by combining cells with porous scaffolds materials. Scaffolds are templates for tissue regeneration and should ensure suitable cell adhesion and mechanical stability throughout the application period. Chitosan (CS) is a biocompatible polymer highly investigated for scaffold preparation but suffers from poor mechanical strength. In this study, graphene oxide (GO) was conjugated to chitosan at two weight ratios 0.3% and 1%, and the resulting conjugates were used to prepare composite scaffolds with improved mechanical strength. To study the effect of GO oxidation degree on scaffold mechanical and biological properties, GO samples at two different oxygen contents were employed. The obtained GO/CS scaffolds were highly porous and showed good swelling in water, though to a lesser extent than pure CS scaffold. In contrast, GO increased scaffold thermal stability and mechanical strength with respect to pure CS, especially when the GO at low oxygen content was used. The scaffold in vitro cytocompatibility using human primary dermal fibroblasts was also affected by the type of used GO. Specifically, the GO with less content of oxygen provided the scaffold with the best biocompatibility.
Correction: Singh, Y. Mahendra, et al. F-Convex Contraction via Admissible Mapping and Related Fixed Point Theorems with an Application. Mathematics 2018, 6, 105
Authors: Singh Y. Mahendra , Khan Mohammad Saeed , Kang Shin Min
Published: April 2019

We found some errors in Lemma 1 of our paper [...]
Observable for a Large System of Globally Coupled Excitable Units
Authors: Boari Santiago , Uribarri Gonzalo , Amador Ana , Mindlin Gabriel B.
Published: April 2019

The study of large arrays of coupled excitable systems has largely benefited from a technique proposed by Ott and Antonsen, which results in a low dimensional system of equations for the system’s order parameter. In this work, we show how to explicitly introduce a variable describing the global synaptic activation of the network into these family of models. This global variable is built by adding realistic synaptic time traces. We propose that this variable can, under certain conditions, be a good proxy for the local field potential of the network. We report experimental, in vivo, electrophysiology data supporting this claim.
Analysis of Association between Dietary Intake and Red Blood Cell Count Results in Remission Ulcerative Colitis Individuals
Authors: Głąbska Dominika , Guzek Dominika , Kanarek Barbara , Lech Gustaw
Published: April 2019

Background and objectives: The anemia is the most common extra-intestinal manifestation of the ulcerative colitis. Taking into account, that meat products are perceived as factor, that may promote relapses, the crucial is to indicate the dietary recommendations to prevent anemia development but without high animal products intake. Aim of the study was to analyze the influence of animal products intake on the red blood cell count results in remission ulcerative colitis individuals and pair-matched control group, during 6 weeks of observation. Materials and Methods: The intake of nutrients associated with anemia development (iron, vitamin B12, protein, animal protein, calcium) and the products being their sources (meat, meat products, dairy beverages, cottage cheese, rennet cheese) were analyzed. Results: In spite of the higher meat products intake in the group of ulcerative colitis individuals, the iron intake did not differ between groups. The positive correlations between intakes of meat, meat products, total protein, animal protein, iron, vitamin B12 and red blood cell count results were stated for ulcerative colitis individuals, while in control group were not observed, that may have resulted from higher susceptibility for the diet-influenced changes. Conclusions: The positive correlation between red blood cell count results and energy value of diet, and daily iron intake observed in ulcerative colitis individuals, accompanied by negative correlation for iron intake per 1000 kcal of diet, may indicate, that higher iron intake may be beneficial, but only while accompanied by high energy value of diet.
Lower Limb Maneuver Investigation of Chasse Steps Among Male Elite Table Tennis Players
Authors: Yu Changxiao , Shao Shirui , Awrejcewicz Jan , Baker Julien S. , Gu Yaodong
Published: April 2019

Background and Objectives: The popularity of table tennis has increased globally. As a result, the biomechanical movement patterns in the lower limb during table tennis have attracted extensive attention from coaches, scientists and athletes. The purpose of this study was to compare the differences between the long and short chasse steps in table tennis and evaluate risk factors related to injuries in the lower limb. Materials and Methods: Twelve male elite athletes performed forehand topspin strokes with long and short chasse steps in this study, respectively. The kinematics data of the lower-limb joints were measured by a Vicon motion analysis system. The electromyograms (EMG) of six lower-limb muscles were recorded using a myoelectricity system. Results: The key findings were that the angle change rate of the ankle in the long chasse step was faster with a larger range of motion (ROM) in the coronal and transverse planes. The hip was also faster in the sagittal and transverse planes but slower in the coronal plane compared with the short chasse step. In addition, the vastus medialis (VM) was the first activated muscle in the chasse step. Conclusions: The hip and ankle joints in the long chasse step and the knee joint in the short chasse step have higher susceptibility to injury. Moreover, tibialis anterior (TA), vastus medialis (VM) and gastrocnemius (GM) should be sufficiently stretched and warmed prior to playing table tennis. The results of this study may provide helpful guidance for teaching strategies and providing an understanding of potential sport injury mechanisms.
Residual Stress Relief for 2219 Aluminum Alloy Weldments: A Comparative Study on Three Stress Relief Methods
Authors: Chen Shu-Guang , Zhang Yi-Du , Wu Qiong , Gao Han-Jun , Yan Dong-Yang
Published: April 2019

Thermal stress relief (TSR), vibration stress relief (VSR), and thermal and vibratory Stress relief (TVSR) have all been proven to be effective for residual stress relief. So far, no comparison has been made between the effects on residual stress relief of these three stress release methods. In this study, twelve 2219 aluminum alloy welding samples were divided into four groups. One of the groups is used as a reference without any stress relief treatment. The other three groups were processed by TSR, VSR, and TVSR, respectively. The residual stresses of depths of 0–1.2 mm are measured. Results show that small and uniform stresses are observed in the 2219 aluminum alloy welding samples after TSR, VSR, and TVSR treatment. TSR treatment decreased the peak residual stress much more than VSR and TVSR treatment. The maximum reduction of the peak residual stress is 50.8% (210 °C) in the transversal direction and 42.02% (185 °C) in the longitudinal direction after TSR treatment with the temperature range 140 °C to 210 °C. In terms of residual stress homogenization, although the TSR treatment has an advantage perpendicular to the weld direction, the effect parallel to the weld direction is not ideal. The TVSR has a good effect in both directions.
Effect of the Pitot Tube on Measurements in Supersonic Axisymmetric Underexpanded Microjets
Authors: Mironov Sergey G. , Aniskin Vladimir M. , Korotaeva Tatiana A. , Tsyryulnikov Ivan S.
Published: April 2019

This paper describes the results of methodical investigations of the effect of the Pitot tube on measurements of gas-dynamic parameters of supersonic axisymmetric underexpanded real and model microjets. Particular attention is paid to distortions of Pitot pressure variations on the jet axis associated with the wave structure of the jet and to distortions of the supersonic core length. In experiments with model jets escaping from nozzles with diameters ranging from 0.52 to 1.06 mm into the low-pressure chamber, the measurements are performed by the Pitot tubes 0.05 to 2 mm in diameter. The results are analyzed together with the earlier obtained data for real microjets escaping from nozzles with diameters ranging from 10 to 340 µm where the parameters of real microjets were determined by the Pitot microtube 12 µm in diameter. Interaction of the Pitot tube with an unsteady jet in the laminar-turbulent transition region is investigated; the influence of this interaction on Pitot pressure measurements is determined, and a physical interpretation of this phenomenon is provided.
Shape Programming Using Triangular and Rectangular Soft Robot Primitives
Authors: Khin Phone , Low Jin , Ang Marcelo , Yeow Chen-Hua
Published: April 2019

This paper presents fabric-based soft robotic modules with primitive morphologies, which are analogous to basic geometrical polygons—trilateral and quadrilateral. The two modules are the inflatable beam (IB) and fabric-based rotary actuator (FRA). The FRA module is designed with origami-inspired V-shaped pleats, which creates a trilateral outline. Upon pressurization, the pleats unfold, which enables propagation of angular displacement of the FRA module. This allows the FRA module to be implemented as a mobility unit in the larger assembly of pneumatic structures. In the following, we examine various ways by which FRA modules can be connected to IB modules. We studied how different ranges of motion can be achieved by varying the design of the rotary joint of the assemblies. Using a state transition-based position control system, movement of the assembled modules could be controlled by regulating the pneumatic pressurization of the FRA module at the joint. These basic modules allow us to build different types of pneumatic structures. In this paper, using IB and FRA modules of various dimensions, we constructed a soft robotic limb with an end effector, which can be attached to wheelchairs to provide assistive grasping functions for users with disabilities.
Highly Integrated MEMS Magnetic Sensor Based on GMI Effect of Amorphous Wire
Authors: Chen Jiawen , Li Jianhua , Xu Lixin
Published: April 2019

In this paper, a highly integrated amorphous wire Giant magneto-impedance (GMI) magnetic sensor using micro electron mechanical system (MEMS) technology is designed, which is equipped with a signal conditioning circuit and uses a data acquisition card to convert the output signal of the circuit into a digital signal. The structure and package of the sensor are introduced. The sensor sensing principle and signal conditioning circuit are analyzed. The output of the sensor is tested, calibrated, and the relationship between the GMI effect of the amorphous wire and the excitation current frequency is explored. The sensor supplies voltage is ±5 V, and the excitation signal is a square wave signal with a frequency of 60 MHz and an amplitude of 1.2 V generated by the quartz crystal. The sensor has the largest GMI effect at 60 MHz with a sensitivity of 4.8 V/Oe and a resolution of 40 nT.
Mechanism of Biomineralization Induced by Bacillus subtilis J2 and Characteristics of the Biominerals
Authors: Han Zuozhen , Wang Jiajia , Zhao Hui , Tucker Maurice E. , Zhao Yanhong , Wu Guangzhen , Zhou Jingxuan , Yin Junxiao , Zhang Hucheng , Zhang Xinkang , Yan Huaxiao
Published: April 2019

Biomineralization induced by microorganisms has become a hot spot in the field of carbonate sedimentology; however, the mechanisms involved still need to be explored. In this study, the bacterium Bacillus subtilis J2 (GenBank MG575432) was used to induce the precipitation of calcium carbonate minerals at Mg/Ca molar ratios of 0, 3, 6, 9, and 12. Bacillus subtilis J2 bacteria released ammonia to increase pH, but the ammonia released only made the pH increase to 8.25. Carbonic anhydrase was also produced to catalyze the hydration of carbon dioxide, and this process released carbonate and bicarbonate ions that not only increased pH but also elevated carbonate supersaturation. The biominerals formed at a Mg/Ca molar ratio of 0 were spherulitic, elongated, dumbbell-shaped, and irregularly rhombohedral calcite; at a Mg/Ca molar ratio of 3, the biominerals were calcite and aragonite, the weight ratio of calcite decreased from 26.7% to 15.6%, and that of aragonite increased from 73.3% to 84.4% with increasing incubation time. At higher Mg/Ca molar ratios, the biominerals were aragonite, and the crystallinity and thermal stability of aragonite decreased with increasing Mg/Ca molar ratios. FTIR results showed that many organic functional groups were present on/within the biominerals, such as C–O–C, N–H, C=O, O–H, and C–H. HRTEM-SAED examination of the ultra-thin slices of B. subtilis J2 bacteria showed that nano-sized minerals with poor crystal structure had grown or been adsorbed on the EPS coating. The EPS of the B. subtilis J2 strain contained abundant glutamic acid and aspartic acid, which could be deprotonated in an alkaline condition to adsorb Ca2+ and Mg2+ ions; this made EPS act as the nucleation sites. This study may provide some references for further understanding of the mechanism of biomineralization induced by microorganisms.
Crystal Chemistry of Chlormagaluminite, Mg4Al2(OH)12Cl2(H2O)2, a Natural Layered Double Hydroxide
Authors: Zhitova Elena S. , Krivovichev Sergey V. , Pekov Igor V. , Yapaskurt Vasiliy O.
Published: April 2019

Chlormagaluminite is the only Cl-dominated hydrotalcite-supergroup mineral species with M2+:M3+ = 2:1. The holotype sample of chlormagaluminite from the Kapaevskaya volcanic pipe (Irkutsk Oblast, Siberia, Russia) has been chemically and structurally characterized. The average chemical composition of the mineral is (electron microprobe, OH content is calculated by stoichiometry and H2O from the crystal-structure data, wt. %): MgO 33.85, FeO 1.09, Al2O3 22.07, Cl 14.72, H2Otot 30.96, Cl=O −3.39, total 99.30. The empirical formula based on Mg + Al + Fe = 6 atoms per formula unit (apfu) is [Mg3.91Fe2+0.07Al2.02(OH)12]Cl2.02(H2O)2.0(2). The crystal structure has been solved from single-crystal X-ray diffraction data in the space group P63/mcm, a = 5.268(3), c = 15.297(8) Å and V = 367.6(4) Å3. The refinement converged to R1 = 0.083 on the basis of 152 unique reflections with I > 2σ(I) collected at room conditions. The powder pattern contains standard reflections of a 2H polytype and two additional reflections [(010), d010 = 4.574 Å; (110), d110 = 2.647 Å] indicative of Mg and Al ordering according to the 3 × 3 superstructure. The structure is based upon brucite-type octahedral layers with an ordered distribution of Mg and Al over octahedral sites. The Cl− anions and H2O molecules reside in the interlayer, providing a three-dimensional integrity of the structure.
Estimating Bubble Loading in Industrial Flotation Cells
Authors: Ostadrahimi Mahdi , Gharibi Khodakaram , Dehghani Ali , Farrokhpay Saeed
Published: April 2019

Bubble loading is the ratio of the weight of the solid particles to the bubble’s surface, and it has an effective role in the flotation efficiency. This paper investigates bubble loading an industrial processing circuit through considering the important role of the bubble diameter in calculating bubble loading, and the effect of the aeration rate and frother dosage on the bubble diameter. The ratio of the weight of solid particles to the bubble volume was estimated to be in the range of 8 to 24 g/L. Although increasing the aeration could result in increasing the weight of the particles attached to the bubbles, the bubble loading was reduced by increasing the aeration rate due to its impact on the bubble diameter and the percentage of bubble surface coverage. For example, when the aeration rate was increased from 45 to 146 m3/h, the bubble loading decreased from 23 to 12 g/L. By increasing the frother dosage from 70 to 150 mL/min, the bubble loading increased from 16 to 19 g/L.
Chemical Composition, Antioxidant and Antihyperglycemic Activities of the Wild Lactarius deliciosus from China
Authors: Xu Zhou , Fu Liang , Feng Shiling , Yuan Ming , Huang Yan , Liao Jinqiu , Zhou Lijun , Yang Hongyu , Ding Chunbang
Published: April 2019

The wild mushroom Lactarius deliciosus from China was studied for the first time to obtain information about its chemical composition, antioxidant, and antihyperglycemic activities. Nutritional value, dietary fiber, fatty acids, metal elements, free sugars, free amino acids, organic acids, flavor 5′-nucleotides, and volatile aroma compounds were determined. Potential antioxidant and antihyperglycemic activities were also tested by investigating 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals scavenging activities, ferric ion reducing activity, as well as α-amylase and α-glucosidase inhibitory activities using ethanol and aqueous extracts. The results showed that L. deliciosus was a good wild mushroom with high protein, carbohydrate, and dietary fiber contents, while low in fat and calorie, extensive unsaturated fatty acids contents, with negligible health risks about harmful metal elements. Twenty kinds of free amino acids were detected with a total content 3389.45 mg per 100 g dw. Flavor 5′-nucleotides including 5′-CMP, 5′-UMP, 5′-IMP, and 5′-AMP were 929.85, 45.21, 311.75, and 14.49 mg per 100 g dw, respectively. Mannitol (7825.00 mg per 100 g dw) was the main free sugar, and quininic acid (729.84 mg per 100 g dw) was the main organic acid. Twenty-five kinds of volatile aroma compounds were identified, acids (84.23%) were the most abundant compounds based on content, while aldehydes (15 of 25) were the most abundant compounds based on variety. In addition, both ethanol and aqueous extracts from L. deliciosus exhibited excellent antioxidant activity. While in antihyperglycemic activity tests, only ethanol extracts showed inhibitory effects on α-amylase and α-glucosidase.
Transparent Electrothermal Heaters Based on Vertically-Oriented Graphene Glass Hybrid Materials
Authors: Cui Lingzhi , Cui Kejian , Ci Haina , Zheng Kaiqiang , Xie Huanhuan , Gao Xuan , Zhang Yanfeng , Liu Zhongfan
Published: April 2019

Transparent heating devices are widely used in daily life-related applications that can be achieved by various heating materials with suitable resistances. Herein, high-performance vertically-oriented graphene (VG) films are directly grown on soda-lime glass by a radio-frequency (rf) plasma-enhanced chemical vapor deposition (PECVD) method, giving reasonable resistances for electrothermal heating. The optical and electrical properties of VG films are found to be tunable by optimizing the growth parameters such as growth time, carrier gas flow, etc. The electrothermal performances of the derived materials with different resistances are thus studied systematically. Specifically, the VG film on glass with a transmittance of ~73% at 550 nm and a sheet resistance of ~3.9 KΩ/□ is fabricated into a heating device, presenting a saturated temperature up to 55 °C by applying 80 V for 3 min. The VG film on the glass at a transmittance of ~43% and a sheet resistance of 0.76 KΩ/□ exhibits a highly steady temperature increase up to ~108 °C with a maximum heating rate of ~2.6 °C/s under a voltage of 60 V. Briefly, the tunable sheet resistance, good adhesion of VG to the growth substrate, relative high heating efficiency, and large heating temperature range make VG films on glass decent candidates for electrothermal related applications in defrosting and defogging devices.
Extremely Polysubstituted Magnetic Material Based on Magnetoplumbite with a Hexagonal Structure: Synthesis, Structure, Properties, Prospects
Authors: Vinnik Denis A. , Zhivulin Vladimir E. , Trofimov Evgeny A. , Starikov Andrey Y. , Zherebtsov Dmitry A. , Zaitseva Olga V. , Gudkova Svetlana A. , Taskaev Sergey V. , Klygach Denis S. , Vakhitov Maxim G. , Sander Elena E. , Sherstyuk Darya P. , Trukhanov Alexey V.
Published: April 2019

Crystalline high-entropy single-phase products with a magnetoplumbite structure with grains in the μm range were obtained using solid-state sintering. The synthesis temperature was up to 1400 °C. The morphology, chemical composition, crystal structure, magnetic, and electrodynamic properties were studied and compared with pure barium hexaferrite BaFe12O19 matrix. The polysubstituted high-entropy single-phase product contains five doping elements at a high concentration level. According to the EDX data, the new compound has a formula of Ba(Fe6Ga1.25In1.17Ti1.21Cr1.22Co1.15)O19. The calculated cell parameter values were a = 5.9253(5) Å, c = 23.5257(22) Å, and V = 715.32(9) Å3. The increase in the unit cell for the substituted sample was expected due to the different ionic radius of Ti/In/Ga/Cr/Co compared with Fe3+. The electrodynamic measurements were performed. The dielectric and magnetic permeabilities were stable in the frequency range from 2 to 12 GHz. In this frequency range, the dielectric and magnetic losses were −0.2/0.2. Due to these electrodynamic parameters, this material can be used in the design of microwave strip devices.
Growth and Functionalization of Particle-Based Mesoporous Silica Films and Their Usage in Catalysis
Authors: Wu Pei-Hsuan , Mäkie Peter , Odén Magnus , Björk Emma M.
Published: April 2019

We report the formation of mesoporous films consisting of SBA-15 particles grown directly onto substrates and their usage as catalysts in esterification of acetic acid and ethanol. The film thickness was altered between 80 nm and 750 nm by adding NH4F to the synthesis solution. The salt also affects the formation rate of the particles, and substrates must be added during the formation of the siliceous network in the solution. Various substrate functionalizations were tested and hydrophobic substrates are required for a successful film growth. We show that large surfaces (> 75 cm2), as well as 3D substrates, can be homogenously coated. Further, the films were functionalized, either with acetic acid through co-condensation, or by coating the films with a thin carbon layer through exposure to furfuryl alcohol fumes followed by carbonization and sulfonation with H2SO4. The carbon-coated film was shown to be an efficient catalyst in the esterification reaction with acetic acid and ethanol. Due to the short, accessible mesopores, chemical variability, and possibility to homogenously cover large, rough surfaces. the films have a large potential for usage in various applications such as catalysis, sensing, and drug delivery.
Direct Observation of Raman Spectra in Black Phosphorus under Uniaxial Strain Conditions
Authors: Liang Stacy , Hasan Md Nazmul , Seo Jung-Hun
Published: April 2019

In this paper, we systematically studied the Raman vibration of black phosphorus (BP) transferred onto a germanium (Ge)-coated polydimethylsiloxane (PDMS) substrate, which generates a much higher contrast in BP. This engineered flexible substrate allowed us to directly observe a much thinner BP layer on the flexible substrate at the desired location. Therefore, it enabled us to perform Raman spectroscopy immediately after exfoliation. The Raman spectra obtained from several BP layers with different thicknesses revealed that the clear peak shifting rates for the Ag1, B2g, and Ag2 modes were 0.15, 0.11, and 0.11 cm−1/nm, respectively. Using this value to identify a 2–3-layered BP, a study on the strain–Raman spectrum relationship was conducted, with a maximum uniaxial strain of 0.89%. The peak shifting of Ag1, B2g, and Ag2 caused by this uniaxial strain were measured to be 0.86, 0.63, and 0.21 cm−1/Δε, respectively.
Biofunctional Nanofibrous Substrate for Local TNF-Capturing as a Strategy to Control Inflammation in Arthritic Joints
Authors: Bacelo Elisa , Alves da Silva Marta , Cunha Cristina , Faria Susana , Carvalho Agostinho , Reis Rui L. , Martins Albino , Neves Nuno M.
Published: April 2019

Rheumatoid arthritis (RA) is an autoimmune disease that affects the synovial cavity of joints, and its pathogenesis is associated with an increased expression of pro-inflammatory cytokines, namely tumour necrosis factor-alpha (TNF-α). It has been clinically shown to have an adequate response to systemic administration of TNF-α inhibitors, although with many shortcomings. To overcome such limitations, the immobilization of a TNF-α antibody on a nanofibrous substrate to promote a localized action is herein proposed. By using this approach, the antibody has its maximum therapeutic efficacy and a prolonged therapeutic benefit, avoiding the systemic side-effects associated with conventional biological agents’ therapies. To technically achieve such a purpose, the surface of electrospun nanofibers is initially activated and functionalized, allowing TNF-α antibody immobilization at a maximum concentration of 6 µg/mL. Experimental results evidence that the biofunctionalized nanofibrous substrate is effective in achieving a sustained capture of soluble TNF-α over time. Moreover, cell biology assays demonstrate that this system has no deleterious effect over human articular chondrocytes metabolism and activity. Therefore, the developed TNF-capturing system may represent a potential therapeutic approach for the local management of severely affected joints.
Modification of Layered Graphitic Carbon Nitride by Nitrogen Plasma for Improved Electrocatalytic Hydrogen Evolution
Authors: Gao Ming , Liu Danni , Yang Huanhuan , Huang Hao , Luo Qian , Huang Yifan , Yu Xue-Feng , Chu Paul K.
Published: April 2019

As a layered nano-sheet material, layered graphitic carbon nitride (g-C3N4) has attracted attention in multifunctional photocatalytic applications. However, g-C3N4 is electrochemically inert consequently hampering electrochemical applications. In this work, low-temperature nitrogen plasma processing was conducted to modify g-C3N4 to enhance the electrocatalytic performance in the hydrogen evolution reaction (HER). The plasma produced significant morphological and chemical changes on the surface of g-C3N4 via active species, and nitrogen atoms were incorporated into the surface while the bulk properties did not change. The modification improved the surface hydrophilicity and electrocatalytic HER activity, as well as excellent stability in HER after 2000 cycles. Our results revealed that plasma treatment was a promising technique to improve the HER of carbon-based layered nano-sheet materials.
A Novel Coloration of Polyester Fabric through Green Silver Nanoparticles (G-AgNPs@PET)
Authors: Hasan K. M. Faridul , Pervez Md. Nahid , Talukder Md. Eman , Sultana Mst. Zakia , Mahmud Sakil , Meraz Md. Mostakim , Bansal Vipul , Genyang Cao
Published: April 2019

This paper reports a novel route for the coloration of polyester fabric with green synthesized silver nanoparticles (G-AgNPs@PET) using chitosan as a natural eco-friendly reductant. The formation of AgNPs was confirmed by UV-visible spectroscopy. The morphologies and average particles size of G-AgNPs was investigated by transmission electron microscope (TEM) analysis. The uniform deposition of G-AgNPs on the PET fabric surface was confirmed with scanning electron microscopy (SEM) and Fourier transform infrared (FT-IR) spectroscopy. The thermal properties were investigated using a thermogravimetric analyzer (TGA). The coloration and fastness properties of fabric were found to be significantly improved, a result related to the surface plasmon resonance of G-AgNPs. The antibacterial properties of fabric were also found to be excellent as more than 80% bacterial reduction was noticed even after 10 washing cycles. Overall, the proposed coating process using green nanoparticles can contribute to low-cost production of sustainable textiles.
Effects of Laser Plasma Formation on Quasi-Phase Matching of High-Order Harmonics from Nanoparticles and Atoms
Authors: Ganeev Rashid A. , Boltaev Ganjaboy S. , Kim Vyacheslav V. , Guo Chunlei
Published: April 2019

The application of nanoparticles (NPs) and quasi-phase matching (QPM) each play an important role in the enhancement of high-order harmonics (HHG) of ultrashort laser pulses. We analyze various regimes of nanoparticle plasma formation for the creation conditions for maximal QPM-induced enhancement of the groups of harmonics in the extreme ultraviolet (XUV). Laser plasmas were formed on the surfaces of NPs- and microparticle (MPs)-contained targets using ablation by nanosecond, picosecond, and femtosecond pulses. Different conditions of laser plasma formation (extended and perforated plasma) and variable concentrations of free electrons in these three cases of laser ablation led to modifications of QPM conditions. We demonstrate novel approaches in the optimization of QPM at the conditions of laser ablation of NPs and MPs by pulses of different durations. The formation of QPM conditions using femtosecond and picosecond heating pulses during HHG in such plasmas allowed the growth of conversion efficiency of the groups of harmonics, with the enhancement factors exceeding 25× in different ranges of XUV, contrary to less efficient QPM in the case of nanosecond pulse-induced ablation.
Fluctuation of Water Intake and of Hydration Indices during the Day in a Sample of Healthy Greek Adults
Authors: Athanasatou Adelais , Kandyliari Aikaterini , Malisova Olga , Kapsokefalou Maria
Published: April 2019

Mild dehydration may occur during specific periods of the day because of poor hydration habits and/or limited access to a variety of beverages or foods, for example, in work environments. Measurement of hydration indices in spot or in 24 h urine samples may mask mild dehydration in specific periods of the day. Healthy subjects (n = 164; 74 females; age 38 ± 12 years) living in Athens, Greece were enrolled in the study. Subjects recorded their solid food and drink intakes and recorded and collected all urinations for three consecutive days. Water intake was analyzed in 24 h and 6 h periods from wake-up time and scored for variety. Urine hydration indices (osmolality, volume, color, specific gravity) were analyzed in 24 h samples, in morning urine samples and in samples collected in 6 h periods from wake-up time. Fluctuations during the day were significant for the intake of drinking water, hot beverages, milk, fruit and vegetable juices, and alcoholic drinks and for urine osmolality, volume, color, and specific gravity. The urine volume of the first 6 h period after wake-up time (557 ± 231 mL/day) reflects by 76% the 24 h urine collection (1331 ± 144 mL/day). Water intake from all beverages, with the exception of alcoholic beverages, was greater in the first 6h period (morning period) and decreased throughout the day. Hydration indices changed accordingly. The 6 h timed urine sample collected reflects indices in samples collected over 24 h better than any spot urine sample.
Investigating Risk of Suboptimal Macro and Micronutrient Intake and Their Determinants in Older Danish Adults with Specific Focus on Protein Intake—A Cross-Sectional Study
Authors: Rønnow Schacht Simon , Vendelbo Lind Mads , Bechshøft Rasmus Leidesdorff , Højfeldt Grith , Reitelseder Søren , Jensen Tenna , Pernille Jespersen Astrid , Sandris Nielsen Dennis , Holm Lars , Tetens Inge
Published: April 2019

Suboptimal intake of nutrients is associated with adverse health outcomes. The current study investigated the risk of suboptimal macro and micronutrient intake and their potential determinants in a cross-sectional study of community-dwelling older Danish adults (65–81 years). Nutrient intake was obtained through a 3-day weighted dietary record and information on personal characteristics and attitudes towards specific foods and dietary habits and nutrition through questionnaires. Dietary Reference Values (DRV) from the Nordic Nutrition Recommendations were used for the assessment. Among 157 participants, 68% and 66% had risk of suboptimal intake of dietary fiber and saturated fatty acids (SFA). For mono-unsaturated fatty acids (MUFA) and poly-unsaturated fatty acids (PUFA), the numbers were 47% and 62%, respectively. Increased risk of suboptimal protein intake was estimated in 3 to 45% of the participants, depending on the criteria used for the DRV and of the mode of expressing protein intake. Fifty percent had intakes of alcohol above the maximum recommended intake. Risk of micronutrient inadequacy was particularly high for vitamin D and thiamine (80 and 45%, respectively). Total energy intake and attitude regarding healthy eating were associated with lower nutrient intake. The current study illustrates that there is room for improvements in the dietary quality of community dwelling older Danish adults.
A Lipophilic Fucoxanthin-Rich Phaeodactylum tricornutum Extract Ameliorates Effects of Diet-Induced Obesity in C57BL/6J Mice
Authors: Gille Andrea , Stojnic Bojan , Derwenskus Felix , Trautmann Andreas , Schmid-Staiger Ulrike , Posten Clemens , Briviba Karlis , Palou Andreu , Bonet M. Luisa , Ribot Joan
Published: April 2019

Phaeodactylum tricornutum (P. tricornutum) comprise several lipophilic constituents with proposed anti-obesity and anti-diabetic properties. We investigated the effect of an ethanolic P. tricornutum extract (PTE) on energy metabolism in obesity-prone mice fed a high fat diet (HFD). Six- to eight-week-old male C57BL/6J mice were switched to HFD and, at the same time, received orally placebo or PTE (100 mg or 300 mg/kg body weight/day). Body weight, body composition, and food intake were monitored. After 26 days, blood and tissue samples were collected for biochemical, morphological, and gene expression analyses. PTE-supplemented mice accumulated fucoxanthin metabolites in adipose tissues and attained lower body weight gain, body fat content, weight of white adipose tissue (WAT) depots, and inguinal WAT adipocyte size than controls, independent of decreased food intake. PTE supplementation was associated with lower expression of Mest (a marker of fat tissue expandability) in WAT depots, lower gene expression related to lipid uptake and turnover in visceral WAT, increased expression of genes key to fatty acid oxidation and thermogenesis (Cpt1, Ucp1) in subcutaneous WAT, and signs of thermogenic activation including enhanced UCP1 protein in interscapular brown adipose tissue. In conclusion, these data show the potential of PTE to ameliorate HFD-induced obesity in vivo.
Effectiveness of an Adult Food Literacy Program
Authors: Begley Andrea , Paynter Ellen , Butcher Lucy M. , Dhaliwal Satvinder S.
Published: April 2019

Nutrition education programs aim to improve food literacy domains covering the planning and management, selection, preparation and cooking and eating of healthy food. Reviews indicate programs are effective but acknowledge challenges with evaluation of community focused delivery. Food Sensations® for Adults (FSA) is a free four-week nutrition and cooking program targeted at low-to-middle income Western Australians who would like to improve their food literacy. The aim of this research was assess how effective FSA is in changing food literacy and selected dietary behaviours. Statistical analysis identified a significant increase in postprogram scores for domains of planning and management, selection and preparation using factor scores (n = 1092). The proportion of the score increase in the postprogram scores compared to the preprogram scores was 10–25%. There was also a significant increase in self-reported fruit and vegetable serve intake, equating to an average increase of ¼ serve/day of fruit and ½ serve/day of vegetables. Of those classified as low food literacy, 61–74% improved postprogram scores in the three domains. FSA is effective in improving food literacy and dietary behaviours and the results add to the evidence base as to how effective these programs can be and for whom they should be targeted for future success.
Fatty Acid Desaturase Involvement in Non-Alcoholic Fatty Liver Disease Rat Models: Oxidative Stress Versus Metalloproteinases
Authors: Palladini Giuseppina , Di Pasqua Laura G. , Berardo Clarissa , Siciliano Veronica , Richelmi Plinio , Mannucci Barbara , Croce Anna Cleta , Rizzo Vittoria , Perlini Stefano , Vairetti Mariapia , Ferrigno Andrea
Published: April 2019

We investigated changes in fatty acid desaturases, D5D, D6D, D9-16D and D9-18D, and their relationship with oxidative stress, matrix metalloproteinases (MMPs) and serum TNF-alpha in two rat models of non-alcoholic fatty liver disease NAFLD. Eight-week-old male Wistar rats fed for 3 weeks with methionine-choline–deficient (MCD) diet and eleven-week-old Obese male Zucker rats were used. Serum levels of hepatic enzymes and TNF-alpha were quantified. Hepatic oxidative stress (ROS, TBARS and GSH content) and MMP-2 and MMP-9 (protein expression and activity) were evaluated. Liver fatty acid profiling, performed by GC-MS, was used for the quantification of desaturase activities. Higher D5D and D9-16D were found in Obese Zucker rats as well as an increase in D9-18D in MCD rats. D6D was found only in MCD rats. A negative correlation between D5D and D9-16D versus TBARS, ROS and TNF-alpha and a positive correlation with GSH were shown in fatty livers besides a positive correlation between D9-18D versus TBARS, ROS and TNF-alpha and a negative correlation with GSH. A positive correlation between D5D or D9-16D or D9-18D versus protein expression and the activity of MMP-2 were found. NAFLD animal models showed comparable serum enzymes. These results reinforce and extend findings on the identification of therapeutic targets able to counteract NAFLD disorder.
Short Chain Fatty Acid Production from Mycoprotein and Mycoprotein Fibre in an In Vitro Fermentation Model
Authors: Harris Hannah C. , Edwards Christine A. , Morrison Douglas J.
Published: April 2019

Dietary mycoprotein (marketed as QuornTM) has many health benefits, including reductions in energy intake. The majority of studies evaluating mycoprotein focus on the protein content and very few consider the fibre content. Fibre consumption is also associated with decreased energy intake, which is partly attributed to short chain fatty acids (SCFAs) from fibre fermentation by colonic bacteria. To study the SCFA-producing capability of mycoprotein, in vitro batch fermentations were conducted, and SCFA production compared with that from extracted mycoprotein fibre, oligofructose (OF), rhamnose, and laminarin. Mycoprotein and mycoprotein fibre were both fermentable, resulting in a total SCFA production of 24.9 (1.7) and 61.2 (15.7) mmol/L, respectively. OF led to a significantly higher proportion of acetate compared to all other substrates tested (92.6 (2.8)%, p < 0.01). Rhamnose generated the highest proportion of propionate (45.3 (2.0)%, p < 0.01), although mycoprotein and mycoprotein fibre yielded a higher proportion of propionate compared with OF and laminarin. Butyrate proportion was the highest with laminarin (28.0 (10.0)% although mycoprotein fibre led to a significantly higher proportion than OF (p < 0.01). Mycoprotein is a valuable source of dietary protein, but its fibre content is also of interest. Further evaluation of the potential roles of the fibre content of mycoprotein is required.
A Scoping Review of the Validity, Reliability and Conceptual Alignment of Food Literacy Measures for Adults
Authors: Amouzandeh Claudia , Fingland Donna , Vidgen Helen Anna
Published: April 2019

The measurement of food literacy has recently gained momentum globally. The aim of this paper is to review the literature in order to describe and analyse the measurement of adult food literacy. The objectives are to i) identify tools that explicitly measure food literacy in adults; ii) summarise their psychometric properties; and iii) critique tool items against the four domains and 11 components of food literacy, as conceptualised by Vidgen and Gallegos. Using the PRISMA guidelines, a search of seven databases (PubMed, Embase, ScienceDirect, Scopus, EBSCOhost, A+ Education, and ProQuest) was undertaken. 12 studies met the inclusion criteria. Papers reported on either the development of a tool to explicitly measure food literacy or a part thereof (n = 5); food literacy strategy indicators (n = 1); tools developed to evaluate a food literacy intervention (n = 3); or tools to measure food literacy as a characteristic within a broader study (n = 3). Six tools captured all four domains. None measured all components. Items measuring the same component varied considerably. Most tools referenced a theoretical framework, were validated and reliable. This review will assist practitioners select and develop tools for the measurement of food literacy in their context.
Reworking Zubarev’s Approach to Nonequilibrium Quantum Statistical Mechanics
Authors: Becattini Francesco , Buzzegoli Matteo , Grossi Eduardo
Published: April 2019

In this work, the nonequilibrium density operator approach introduced by Zubarev more than 50 years ago to describe quantum systems at a local thermodynamic equilibrium is revisited. This method, which was used to obtain the first “Kubo” formula of shear viscosity, is especially suitable to describe quantum effects in fluids. This feature makes it a viable tool to describe the physics of Quark–Gluon Plasma in relativistic nuclear collisions.
ApiAP2 Transcription Factors in Apicomplexan Parasites
Authors: Jeninga Myriam , Quinn Jennifer , Petter Michaela
Published: April 2019

Apicomplexan parasites are protozoan organisms that are characterised by complex life cycles and they include medically important species, such as the malaria parasite Plasmodium and the causative agents of toxoplasmosis (Toxoplasma gondii) and cryptosporidiosis (Cryptosporidium spp.). Apicomplexan parasites can infect one or more hosts, in which they differentiate into several morphologically and metabolically distinct life cycle stages. These developmental transitions rely on changes in gene expression. In the last few years, the important roles of different members of the ApiAP2 transcription factor family in regulating life cycle transitions and other aspects of parasite biology have become apparent. Here, we review recent progress in our understanding of the different members of the ApiAP2 transcription factor family in apicomplexan parasites.