bluuebunny/crossref_metadata_2025 huggingface dataset:
Transient global amnesia after COVID-19: A systematic scoping review of case reports
Authors: Farjoud-Kouhanjani Mohsen , Shafie’ei Mohammad , Taghrir Mohammad Hossein , Akbari Zahra , Amir Hashemi Seyed Mohammad , Eghlidos Zahra , Borhani-Haghighi Afshin , Rahimi-Jaberi Abbas
Published: January 2023

Background: Transient global amnesia (TGA) is a sudden-onset transient memory impairment along with intact neurologic examinations. Even though it is a benign neurologic condition with many differential diagnoses, the incidence rate of TGA is reported to have increased since the onset of the pandemic. Therefore, this systematic scoping review aims to investigate TGA in that context.
Methods: MEDLINE, Scopus, and Google Scholar databases were systematically searched for relevant articles with a string of specified keywords.
Results: The primary search yielded 90 studies. After all the necessary screening rounds were carried out, we were left with six included studies. One study was also identified through a search in other relatively relevant databases. Finally, seven case reports were accepted including three TGA patients with positive and one with negative test for coronavirus disease-2019 (COVID-19), respectively. COVID-19 status was unclear in the others.
Conclusion: The reported COVID-19 positive cases had presentations similar to those with TGA before the pandemic. Therefore, we think that TGA might occur concomitantly with the COVID-19 infection or due to the psychological impact of the pandemic. In the confirmed cases of TGA and COVID-19, the abnormal findings may be due to COVID-19 infection. However, the reports were not as complete as desired. Therefore, providing the readers with more detailed reports in future cases is recommended.
Initial clinical presentation of multiple sclerosis with concurrent COVID-19 infection: Case report and literature review
Authors: Ebadi Zahra , Naser Moghadasi Abdorreza
Published: January 2023

The Article Abstract is not available.
Clinical, Laboratory, Cytometry and Cytogenetic Characteristics of a Cohort of Patients Diagnosed with Multiple Myeloma for the First Time in a Third-Level Hospital in Medellín, Colombia, Survival after 8 Years of Follow-Up
Authors: Atencia-Flórez Carlos , Quintero-Valencia Catalina , Mondragón-Arismendy María , Cardona-Arias Andrés , Regino-Agamez Carlos , Vélez-Urrego Julián
Published: January 2023

Background:  Multiple myeloma is the second most common hematologic malignancy after lymphomas. Few studies have characterized significant and full variables at the time of diagnosis of multiple myeloma in Colombia, and there is no data evaluating patients for follow-up.
Materials and Methods:  A retrospective cohort study is presented, describing the clinical, laboratory, cytometric, and cytogenetic characteristics of patients with a de novo diagnosis of multiple myeloma evaluated in a reference hematology laboratory attached to a highly complex hospital in Medellín, Colombia.  We follow them until death as a main outcome.
Results:  A total of 170 patients with a de novo diagnosis of multiple myeloma were collected from a database of 421 patients with different monoclonal gammopathies. Mainly, it was found that 50.8% of the patients were men; the median age was 62 years; 65.4% had secretion of the IgG kappa; half of the patients presented International Staging System (ISS) Stage III. The β2 macroglobulin >4 mg/L and creatinine >2 mg/dl were the main variables significantly associated with survival (Hazard Ratio (HR) 2.4 and 2, respectively). Eighty-five percent of patients presented with bone lytic lesion involvement and less than 3% with extramedullary involvement. Conventional Banding Karyotype (CBK) genetic risk assessment yield was poor, compared with although scarce data regarding Cytogenetic risk assessment based on Fluorescence in-situ Hybridization (FISH).
Conclusion:  The clinical profile of the patients with a de novo diagnosis of multiple myeloma in our cohort is similar to that described in international studies. The diagnosis of multiple myeloma was documented at younger ages, with more advanced stages, anemia, and a high percentage of bone disease. ISS provides an excellent tool for prognosis purposes. Cytogenetic risk assessment based on FISH should be done for all MM patients from therapeutic implications. We need standardized protocols for bone marrow sample manipulation and processing in order to guarantee good correlation for plasma cells count methods.
Legal aspects of fiscal enforcement in the Second Polish Republic
Authors: Nieścior Bartosz
Published: January 2023

Purpose of the study: The research goal of the article was to analyze the fiscal enforcement model in the Second Polish Republic's legal system. The research problems are: whether the enforcement activities carried out had a clear legal basis; were the enforcement actions carried out without charge at the time they were carried out?

Methodology: The article was prepared based on the literature on the legal aspects of fiscal enforcement in the Second Polish Republic. "Desk research" is the method that was used in the analysis.

Main findings: The fiscal enforcement institution in the Second Polish Republic fulfilled its role, as well as the normative acts issued by the legislator regulating its scope, also through numerous amendments, accurately adapted the enforcement provisions to the then dynamically changing legal reality.

Application of the study: The article refers to the legal aspects related to the institution of fiscal enforcement in the Second Polish Republic. The article's content may be helpful for historians and lawyers dealing with aspects of fiscal enforcement in the Second Polish Republic.

Originality/Novelty of the study: The article concerns the legal aspects of fiscal enforcement in the interwar period in Poland. The study indicates the legal basis for enforcement, the public authorities responsible for it, and its types. It should be recognized that fiscal enforcement significantly evolved in the early years of the independent Polish state. The legal regulations governing execution until the first half of the Second Polish Republic were modelled on those from the period of partitions, and numerous amendments were introduced only later.
Dynamics of structural and functional characteristics of the heart in patients after myocardial infarction with ST segment elevation as a marker of progression of chronic heart failure
Authors: Karetnikova V. N. , Berns S. A. , Shmidt E. A. , Artemova T. P. , Shepel R. N. , Barbarash O. L.
Published: January 2023

Objective. To identify the association of a number of clinical features and structural and functional characteristics of the heart with the progression of chronic heart failure (CHF) in patients one year after ST-segment elevation myocardial infarction (MI) (STEMI) with preserved and reduced left ventricular ejection fraction (EF) (LVEF).

Design and methods. 120 patients with STEMI were included in a prospective study. During the study, all patients underwent an echocardiographic study using a Sonos 2500 device (Hewlett Packard, USA) on the 1st day (point I), on the 12th day (point II) of hospitalization, and also after 1 year (point III). Depending on the parameters of EF on the 1st day of the disease, the total sample of patients was divided into two: the 1st group — with preserved LVEF was represented by 86 (71,7 %), the 2nd group — with a reduced LVEF was represented by 34 (28,3 %) patients.

Results. A total of 19 (15,8 %) adverse events were registered. In two cases, a fatal outcome (1,7 %) was recorded, the cause of which was repeated MI, in five (4,2 %) patients decompensation of СHF was noted, in eight (6,7 %) patients a clinic of progressive angina was traced, in four (3, 3 %) of patients were diagnosed recurrent MI. Deterioration of systolic and diastolic function was established one year after STEMI with preserved (≥ 50 %) LVEF: 17,6 % of patients began to correspond to the intermediate range of EF (40-49 %), the number of patients with diastolic dysfunction increased by 10 % compared to with acute study.

Conclusions. Within a year after a STEMI with initially preserved LVEF, there is a deterioration in myocardial function in the form of a decrease in myocardial contractility and an increase in the number of patients with diastolic dysfunction.
The Power of Poetic Praxis in the Literature of Pat Mora and Ana Castillo
Authors: Graf Amara
Published: January 2023

Chicana literary work is predominantly characterized by poetry. Lyrical poetic phrases are interwoven into Chicanas’ short stories, novels, theoretical, and critical essays. Why poetry? What is distinct about poetry as a literary genre or the process of writing poetry that facilitates Chicanas’ self-expression? Various Chicana writers refer to the process of writing poetry as essential to the (trans)formation of identity and society. Poetry allows Chicanas to transform their own identities and to re-define the contours of the world by creating a new or distinct reality from which to act. Collectively, Chicana writers produce a corpus of literary work that is characterized by the commingling of poetry, theory, and criticism. In this article I illustrate that these three phenomena are inextricably linked and that theoretical and critical essays written by and about Chicanas often grow out of and through their more creative, poetic literary work. My analysis focuses primarily on two Chicana authors, Pat Mora and Ana Castillo, and examines how their poetry exemplifies and contextualizes some of their abstract claims and critical theories, as well as how the blending of poetry, theory, and criticism functions as a powerful tool to create socio-political change both in the academy and beyond.
Roll a Hard Six: Losing Your Noodle in Raymond Federman’s Double or Nothing
Authors: Guenther Shawna
Published: January 2023

Raymond Federman’s Double or Nothing is a convoluted representation of the mentallyunstable mind existing as a series of six characters that are at once separate and conjoined: the horrors and traumatic events of the narrative past dismantle the unified subject into a series of schizophrenic sub-personalities, parts of the destabilized Author’s psyche, existing as separate fragments that eventually collide. Further, the imaginary room emerges as the Fifth Person, promising, but failing, to be a central stabilizer of the other fractured selves. Finally, the design of the text echoes the patterns of the traumatized mind, illustrating the inability of a narrative to construct a stable, unified subject and demonstrating the inadequacy of traditional narrative forms. The text, with its obliterations, cropped phrases, and pictorial manifestations, becomes the Sixth Person. However, in the end, the text shows that the past cannot be erased, explained, or reversed; neither can the experimental nature of the novel reach beyond the traumatized, schizoid subject to represent the horrors of the past that caused the Author’s psychotic breach. Federman has rolled a hard six that will repeatedly fragment and unite, just as the traumatic past continues to repeat itself as one that defies representation.
The use of digital tools in French as a Second Language teacher education in Ontario
Authors: Boreland Taylor , Lotherington Heather , Tomin Brittany , Thumlert Kurt
Published: January 2023

This article discusses a 2021 survey of French as a second language (FSL) teacher candidates (TCs) in Faculties of Education in Ontario whose practice teaching experiences were affected by the COVID-19 pandemic, pivoting them into remote FSL teaching and learning. The survey, which formed a component of a larger mixed method SSHRC-funded research project1, was designed to capture the varied practice teaching experiences of FSL teacher candidates in order to ascertain symmetries and asymmetries in their preferred digital practices, devices and tools for social communication, and for French language teaching and learning. Survey respondents (N=17) from different teacher education programs in universities across Ontario provided a picture of scattered and fragmented approaches to FSL digital pedagogies and hinted at a persistent reliance on traditional FSL pedagogies in the classroom. Digital preferences for teaching and learning were, interestingly, not parallel, and were anchored in common educational tools and platforms that reaffirmed teacher-centred approaches to FSL rather than more innovative, learner-centred, and agentive language teaching and learning. The survey results raise an important question: Has FSL teacher education adequately moved with the communicative changes wrought by socio-technical change and related pedagogical innovations?
Asymetric Pass-through Effects of Oil Price Shocks and Exchange Rates on Inflation in Nigeria: Evidence from a Nonlinear ARDL Model
Authors: Sa’ad Suleiman , Usman Ali Baba , Omaye Solomon Ochada , Yau Hamisu
Published: January 2023

By utilizing the non-linear ARDL (NARDL) model developed by Shin, et al (2014), we examined the asymmetric effect of oil price and exchange rates pass-through on inflation in Nigeria over a period of 1970 to 2020. Result of asymmetric test revealed the existence of asymmetries among the variables of the study, suggesting that there is a nonlinear interaction among the variables used in the study. This validates the choice of non-linear ARDL model for the study. Result of the long-run estimates show that rising (Positive) oil price shocks have a greater impact on inflation than falling (negative) oil price shock. Furthermore, ot is evident form the result that depreciation of exchange rate has much and significant effect on inflation than the appreciation of exchange rate in Nigeria. However, rising interest rate increases inflation by 0.84 per cent while falling interest rate increases inflation by 0.85 per cent. This implies that the effect of negative interest rate on inflation is higher than its positive effect on inflation, though, by a smaller amount of about 0.01 per cent. Again, the short-run dynamic model revealed a high speed of convergence of more than 90% from the short run disequilibrium. During the study period, the oil price fluctuations showed a significant and incomplete pass-through to both exchange rates and inflation in Nigeria. Based on the findings, the study recommends policies that set oil prices and exchange rate within reasonable limits in order to chack inflation in Nigeria.
ОСОБЕННОСТИ ЭЛЕМЕНТНОГО СТАТУСА ВЗРОСЛОГО НАСЕЛЕНИЯ ГОРОДА ЯРОСЛАВЛЯ
Authors:   Ярославский государственный университет им. П.Г. Демидова (ЯрГУ им. П. Г. Демидова), Мазалецкая А.Л. , Скальный А.А. ,   Российский университет дружбы народов (РУДН), Серебрянский Е.П. ,   ООО «Микронутриенты», Грабеклис А.Р. ,   Ярославский государственный университет им. П.Г. Демидова (ЯрГУ им. П. Г. Демидова), Зайцева Ю.В. ,   Ярославский государственный университет им. П.Г. Демидова (ЯрГУ им. П. Г. Демидова), Флерова Е.А. ,   Ярославский государственный университет им. П.Г. Демидова (ЯрГУ им. П. Г. Демидова), Тиньков А.А. ,   Ярославский государственный университет им. П.Г. Демидова (ЯрГУ им. П. Г. Демидова)
Published: January 2023

Цель исследования − изучение особенностей элементного статуса взрослого населения города Ярославля. Материалы и методы. Обследовано 178 взрослых жителей г. Ярославля в возрасте от 20 до 80 лет (99 мужчин и 79 женщин), не занятых в производственной сфере. Дополнительно проведено обследование 113 взрослых лиц (49 мужчин и 64 женщины), которые рассматривались в качестве группы сравнения. Определение содержания микроэлементов проводилось методом масс-спектрометрии с индуктивно-связанной плазмой. Результаты. При сравнении с референтными значениями установлено увеличение частоты избыточной кумуляции токсичных металлов в волосах жителей г. Ярославля свыше 10%, в первую очередь, кадмия, никеля, свинца и олова. В то же время частота превышения верхней границы референтных значений для содержания алюминия в волосах составила более 20%. На этом фоне обращает на себя внимание высокая частота низкого уровня кобальта, меди, ванадия и цинка. При сравнении полученных данных с группой сравнения установлено, что содержание алюминия, кадмия, никеля, а также олова у обследуемых из г. Ярославля выше на 30, 63, 34 и 28%. Уровень селена и цинка в волосах обследуемых из г. Ярославля оказался ниже такового в группе сравнения на 32 и 9% соответственно. Вместе с тем содержание ванадия в волосах жителей г. Ярославля отмечалось ниже соответствующих значений в группе сравнения в 2 раза. Уровень железа в волосах жителей г. Ярославля превышал соответствующие показатели группы сравнения на 31%. Выводы. Взрослые жители г. Ярославля характеризуются избыточной кумуляцией алюминия, кадмия, свинца, олова и железа на фоне риска развития дефицита цинка и ванадия. Выявленные нарушения элементного статуса могут вносить значительный вклад в развитие экологически-обусловленной патологии у населения.
УЛЬТРАДИСПЕРСНЫЕ ЧАСТИЦЫ ЖЕЛЕЗА В ЖИВОТНОВОДСТВЕ (обзор)
Authors:   ФГБНУ ФНЦ Биологических систем и агротехнологий РА, Гарипова Н.В, , Рязанов В.А. ,   ФГБНУ ФНЦ Биологических систем и агротехнологий РА
Published: January 2023

Нанотехнологии привлекают большой интерес исследователей. Бурное развитие нанотехнологий в последние десятилетия обусловлены тем, что ультрадисперсные частицы, в том числе металлов, обладают совершенно иными свойствами, чем традиционные формы химических элементов. В настоящее время особенно перспективным выглядит применение ультрадисперсных частиц металлов в области сельского хозяйства. Достоинство новых форм микроэлементов состоит в том, что с их помощью возможно преодолеть негативные эффекты, присущие традиционным формам. Так, традиционным формам элементов присущи невысокая усвояемость в организме и вероятность развития окислительного стресса у животных, поэтому при составлении рационов животных и птицы необходимо тщательно подбирать дозы элементов во избежание их токсического действия. Всё это послужило толчком для изучения применения ультрадисперсных частиц как источников микроэлементов в рационе сельскохозяйственных животных. Данный обзор посвящен применению ультрадисперсных частиц железа в качестве кормовой добавки в рационах сельскохозяйственных животных и птицы.
СОПРЯЖЕННОСТЬ ПАРАМЕТРОВ КОСТНОГО МЕТАБОЛИЗМА С МИНЕРАЛЬНОЙ ПЛОТНОСТЬЮ КОСТИ У ЖЕНЩИН Г. ХАНТЫ-МАНСИЙСКА В ПЕРИОДЕ ПОСТМЕНОПАУЗЫ
Authors:   Ханты-Мансийская государственная медицинская академия, Сухарева А.С. , Зиновьева А.В. ,   Ханты-Мансийская государственная медицинская академия, Корчина Т.Я. ,   Ханты-Мансийская государственная медицинская академия, Корчин В.И. ,   Ханты-Мансийская государственная медицинская академия, Угорелова Е.А. ,   Ханты-Мансийская государственная медицинская академия
Published: January 2023

Цель работы – изучение корреляционных связей между биохимическими показателями костного метаболизма и показателями минеральной плотности костной ткани у женщин северного региона в периоде постменопаузы. Материалы и методы. Обследовано 169 женщин в возрастном диапазоне 52–69 лет, проживающих в г. Ханты-Мансийске более 10 лет. Концентрацию параметров костной деструкции (паратгормон, щелочная фосфатаза, β-CrossLaps) и костеобразования (эстрогены, витамин D, Са, Mg, P, Zn, Cu, Si, Mn) определяли по общепринятым методикам. Результаты. Установлен дефицит концентрации витамина D (95,5%) и недостаточность концентраций биоэлементов, принимающих участие в формировании костной ткани (32,5–12,4%) на фоне увеличения параметров резорбции костей (26,6–3,6%). Выводы. Выявленные прямые статистически значимые взаимосвязи между показателем минеральной плотности костной ткани (МПК), обеспеченности организма женщин витамином D и биоэлементами, а также обратные взаимосвязи между МПК и параметрами костной деструкции свидетельствуют о возможности замедления развития остеопороза путем оптимизации обеспеченности женщин в период постменопаузы витамином D и биоэлементами.
ЭЛЕМЕНТНЫЙ СОСТАВ ПЛАЗМЫ И ЭРИТРОЦИТОВ КРОВИ КАК МАРКЕР ПЕРИНАТАЛЬНОЙ ПАТОЛОГИИ
Authors:   Казанский государственный медицинский университет Министерства здравоохранения РФ, Софронов В.В. , Волошин А.В. ,   Казанский (Приволжский) федеральный университет Министерства образования РФ, Скворцова Г.Ш. ,   Казанский (Приволжский) федеральный университет Министерства образования РФ
Published: January 2023

Цель исследования – выделение из группы элементов (медь, хром, марганец, селен, магний, цинк, стронций) тех, концентрация которых в компонентах крови (плазме и эритроцитах) может быть использована в качестве маркеров для прогнозирования патологии новорожденных. Материалы и методы. Под наблюдением находились 98 пар доношенных новорожденных и их матерей, из них 58 пар из отделения патологии и 40 условно здоровых пар (контрольная группа сравнения). Концентрацию химических элементов проводили методом масс-спектрометрии с индуктивно связанной аргоновой плазмой. Выполнены статистическая обработка, факторный и компонентный анализ полученных количественных значений концентраций элементов в плазме и эритроцитах периферической крови. Результаты. Выявлены группы с экстремальными значениями фактора. Для каждой из групп определены средние показатели анамнестических данных рожениц и данных клинического статуса новорожденных раннего неонатального периода. Для группы «Фактор I «−1» концентрации элементов магний и медь в крови у матери и новорожденного отмечались значительно больше физиологической нормы, что приводит к уменьшению срока гестации и массы новорожденного, увеличению степени задержки внутриутробного развития. В случае группы «Фактор II «+1», концентрации марганца и хрома оказались больше физиологической нормы, в результате чего возрастает вероятность возникновения у новорожденных патологии «Синдром вегето-висцеральных нарушений». Выводы. В качестве маркера перечисленных патологий возможно использовать совместное превышение физиологической нормы концентрации пар элементов магний/медь и марганец/хром в компонентах крови беременных.
En la soledad del taxi
Authors: Madueño Álvarez Miguel , Re Matteo
Published: January 2023

En el siguiente artículo, los autores analizan el asesinato de taxistas por parte de la banda terrorista ETA. A partir de fuentes primarias, se analiza como los atentados de los taxistas constituyeron una herramienta de control utilizada por la organización terrorista para conseguir someter a la ciudadanía a un régimen de terror. Asimismo, el acoso constante al gremio del taxi fue parte de una estrategia que tuvo como objetivo aislar a los agentes de la Policía y de la Guardia Civil, creando a su alrededor un vacío y una oposición hostil.
Franceses, ultras y moderados
Authors: Butrón Prida Gonzalo
Published: January 2023

Este trabajo analiza los pulsos y tensiones causados por la política de moderación inspirada por Francia en 1823 como alternativa al régimen constitucional español. La propuesta francesa apenas convenció a una minoría moderada, mientras que sus aliados realistas se aferraron al absolutismo y se resistieron con fuerza a las concesiones políticas, haciendo inútil en este sentido el enorme esfuerzo militar y económico realizado por Francia durante la campaña militar. A partir de octubre, una vez liberado del control constitucional, Fernando VII confirmó esa misma línea intransigente y evitó dar su visto bueno a cualquier cesión, por moderada que fuera. Promovió además una política de castigo al vencido, que trató de imponer a pesar de la presión ejercida por sus aliados para que concediera una amnistía amplia.
Alternativas y posicionamientos en torno a la guerra entre patriotas y realistas en el espacio andino
Authors: Davio Marisa
Published: January 2023

A partir del estudio de un caso judicial, relativo a un actor realista natural de Lima involucrado en el proceso de independencia y colaborador del General José de San Martín, nos preguntamos acerca de las estrategias y alternativas de los realistas -y revolucionarios- durante el conflicto que duró más de veinte años en el espacio andino, desde el largo proceso iniciado con la crisis de la monarquía española en 1808 hasta las declaraciones formales de independencia en los últimos bastiones realistas que aún quedaban en estos territorios. Pretendemos observar el panorama político que experimentaron múltiples actores contemporáneos que debieron optar por la lucha a favor de uno u otro bando en pugna, de acuerdo con sus convicciones y pretensiones políticas y económicas, a raíz de incertidumbre derivada de la crisis monárquica de 1808 y el inicio del proceso revolucionario en 1810 que derivaría en la independencia de los países en Sudamérica.
M.A. Voloshin’s works in periodicals of southern Russia between 1917 and 1922
Authors:   Lomonosov Moscow State University, Orlova Ekaterina I. ,   Gorky Institute of World Literature of the  Russian Academy of Sciences
Published: January 2023

Very few works written by Maximilian Voloshin during the Russian Civil War were published in Southern Russia’s periodicals or other printed media. Nonetheless, papers like Tavrichesky Golos (Simferopol) and Delo (Odesa), the Kamena magazine (Kharkiv), as well as a literary and political volume called Nakanune (Yekaterinodar, modern-day Krasnodar) published some of Voloshin’s poems and articles. These publications are, without a doubt, highly significant for the history of literature and journalism as Moscow and Saint Petersburg media published Voloshin’s works less often; nowadays, his publications in periodicals of Southern Russia are considered to be important textual sources. Voloshin’s attitude towards the events of the Russian Civil War in his lectures matches the understanding of those events in his poems of that period. The article called Poetry and Revolution. Alexander Blok and Ilya Erenburg, as well as Voloshin’s personal letters provide a key to his understanding of poetry and the relations between poetry, politics, and journalism. Therefore, it is fair to say that Voloshin had his own unique system of art comprehension. Analysis of its evolution, as well as studying Voloshin’s publications in the context of Southern Russia’s periodicals are yet the challenge of the future.
Literary literature in Russian provincial journalism of the early 20th century
Authors:   Russian State University for the Humanities, Orlitskiy Yuri B.
Published: January 2023

This article examines the range of real forms and genres of Russian journalism in the early 20th century, in one way or another related to literature, using newspapers from Nizhny Novgorod, Vladimir and Yaroslavl provinces as a case study; Nizhny Novgorod Leaf of 1912–1913 was chosen as the main study material. The study showed the importance of the literary component of the repertoire of a provincial newspaper, the variety of forms of presence of literature, both modern and classical, on the newspaper page. Literature itself is represented in the repertoire by poems, prose miniatures, and stories, often printed with a continuation. Humorous and satirical texts, literary parodies occupy an important place in the newspaper. The main object of critical reflection and parody in 1913 became I. Severyanin and other ego-futurists. Besides, the Leaflet regularly publishes critical and biographical articles, reviews, obituaries, retellings of book market novelties, publications of previously unknown works and memoirs, memoirs, reports on events of literary life. The main heroes of the newspaper of 1912–1913 are Turgenev, Nadson, L. Tolstoy, Gorky (as a famous countryman), Balmont. The main informational occasion for the appearance of literary materials in the newspaper are anniversaries or the publication of interesting books or publications. A significant part of literary publications are reprints from publications in the capital. The newspaper also pays a certain amount of attention to foreign literature, first of all, modern literature; O. Wilde, A. Strindberg, H. Hauptmann, and A. Frans. Particular attention is paid to the prose miniature (poem in prose), a specific newspaper genre characteristic of early twentieth-century periodicals. The large number of articles on literary themes testifies to the general literary centrism of early twentieth-century Russian culture.
“Hacked beauty”: A readerly rewriting of a text as a communicative strategy in regional avant-garde discourse
Authors:   Lomonosov Moscow State University, Shvets Anna V.
Published: January 2023

The paper focuses on a poetic discourse of the avant-garde poetic community “41º” (A. Kruchenykh, I. Terentyev, I. Zdanevich). Unlike the public actions of “classic” avant-garde (futuristic) communities, “41º” relied less on scandal as a means to attract the attention of the “newshawk”, a relay of a public action for a broader audience. Regional journalists, literary critics sympathized with the futurists and included them into their creative community. Their attention did not have to be attracted on purpose. Scandal has been replaced by cooperation. Therefore, the communicative strategy that has developed in the “41º” community is predicated on a dialogue, it implies the activity of the reader. It as a consequence, the reader parodies the poet-orator. The reader deliberately alters and then creatively twists the poet’s statement, appropriating the device and becoming the author himself, a subject expressing feelings. This strategy becomes topical in A. Kruchenykh and I. Terentyev poetic theory as part of the “readerly” program. A quest “mistakes” (textual zones subject to a parodic recoding) in someone else’s text is foregrounded. A “mistake” (“shift”) makes it possible to reimagine the text as a semiotic object and reassign its reference to a readerly intention not coinciding with the authorial one, so that the reader as a co-performer becomes a co-author. The purpose of text misreading (“hacking”) is to shift the focus from the “I” of the writing subject and from the printed statement to the context as a source of creativity and to the performer’s gesture as the referent of the statement.
“Novgorod Leaflet” (1881–1882): In search of relevant regional identity
Authors:   Yaroslav the Wise Novgorod State University, Semenova Aleksandra L.
Published: January 2023

The article is devoted to the history of the first private universal newspaper “Novgorod Leaflet” (1881–1882), which was the only edition of this kind in the 19th century Novgorod province. Several petitions for the publication of a private newspaper in Novgorod in the second half of the 19th century were rejected by the Main Directorate for Press Affairs. Yakov Eliashevich, a teacher at the Novgorod gymnasium, was the only one of the petitioners who received the right to publish this popular type of newspaper. The article analyzes the activity of this edition as a way of expressing an actual regional identity, which was especially important for a territory with a vivid medieval history, but with an ordinary provincial way of life in modern times. The identified personalities of the authors of the publications of the “Novgorod Leaflet” show that it involved representatives of the Novgorod intelligentsia not only from the provincial center, but also from the districts of the province. The topics of the newspaper reflected the professional interests of its employees, and the rubrication was characteristic of a universal newspaper. The authors study the documents from the funds of the Russian State Historical Archive, disclosing the conditions of the appearance and functioning of the first private newspaper of Novgorod, the peculiarities connected with its censorship, and the reasons for its closure. The history of this newspaper is an example of the opposition of the local intelligentsia and the government. The former needed the newspaper as a means of forming a modern Novgorod identity and discussing topical issues and problems, while the latter were interested in preserving the most positive image of the province in the eyes of the capital.
Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma
Authors: Errazquin Ricardo , Carrasco Estela , Del Marro Sonia , Suñol Anna , Peral Jorge , Ortiz Jessica , Rubio Juan C. , Segrelles Carmen , Dueñas Marta , Garrido-Aranda Alicia , Álvarez Martina , Belendez Cristina , Balmaña Judith , Garcia-Escudero Ramon
Published: January 2023

Fanconi anemia (FA) patients display an exacerbated risk of oral squamous cell carcinoma (OSCC) and precursor lesions at young ages, mainly at the oral cavity. As patients have defects in DNA repair mechanisms, standard-of-care treatments to OSCC such as radiotherapy and chemotherapy give rise to severe toxicities. New methods for early diagnosis are urgently necessary to allow treatments in early disease stages and achieve better clinical outcomes. We have conducted a prospective, longitudinal study whereby liquid biopsies from sixteen lesion/tumor-free patients were analyzed for the presence of mutations in cancer genes. DNA from saliva and plasma were sequentially collected and deep-sequenced, and the clinical evolution followed during a median time of around 2 years. In 9/16 FA patients we detected mutations in cancer genes (mainly TP53) with molecular allele frequencies (MAF) down to 0.07 %. Importantly, all patients having mutations and clinical follow-up data after mutation detection (n=6) developed oral precursor lesions or OSCC. Lead-time between mutation detection and tumor diagnosis ranged from 23 to 630 days. Strikingly, FA patients without mutations display significantly lower risk of developing precursor lesions or OSCC. Therefore, our diagnostic approach could help to stratify FA patients into risk groups, which would allow closer surveillance for OSCC or precursor lesions.
Principles of Specific Treatment and Palliative Care in Advanced Head and Neck Cancer
Authors: Rahnea-Nita Roxana-Andreea , Toma Radu Valeriu , Grigorean Valentin Titus , Anghel Rodica-Maricela , Rebegea Laura Florentina , Corobcean Nadejda , Stoian Alexandru-Rares , Ciuhu Anda-Natalia , Badiu Cristinel-Dumitru , Rahnea-Nita Gabriela , Stoleriu Gabriela
Published: January 2023

Most head and neck cancers are diagnosed in advanced stages, when the curative interventions are no longer possible. The assessment and the multidisciplinary therapeutic approach of the locally advanced cases are difficult since the onset of the disease becomes a significant challenge for the whole attending team (including both the patient and his family) because they have to deal with to an extensive symptomatology (abundant secretions, refractory pain, mutilations predominantly in the cephalic area), with the cure of stomas (tracheostomy, gastrostomy) and with various post-therapeutic sequelae. The present paper reflects the impact of late diagnosis, the complexity of the multimodal specific oncological treatment (chemotherapy, radiotherapy, immunotherapy, pal-liative and terminal treatment), the adaptation of medical care to the psycho-emotional structure, having as an example the case of 54-year old patient (with his consent) diagnosed with pharyn-golaryngeal neoplasm who presented himself to “St. Luca” Chronic Disease Hospital, the Oncol-ogy-Palliative Care Department, in September 2021. In patients with locally advanced head and neck cancers, besides the specifically oncological therapeutic decisions, the empathic-emotional connection between the medical team with the patient and his family plays a key role in the ther-apeutic conduct.
Perсhlozone Resistance in Clinical Isolates of Mycobacterium tuberculosis
Authors: Ushtanit Anastasia , Mikhailova Yulia , Krylova Ludmila , Grigorash Dmitry , Makarova Marina , Safonova Svetlana , Zimenkov Danila
Published: January 2023

The emergence of drug-resistant tuberculosis forced the development of new drugs and screnning of more effective or less toxic analogs. Mycolic acids biosynthesis is targeted by several antituberculosis drugs toped by the isoniazid being one of the most important in tuberculosis therapy. Recently, perchlozone, acting on another step in FAS-II cycle, received official approval and was included in the Russian national clinical guidelines. Using the serial dilution method on agar 7H10 plates for perchlozone and Sensititre MYCOTB microdilution plate we analyzed the phenotypic properties of primary M. tuberculosis clinical isolates and analyzed the molecular determinants of resistance to isoniazid, ethionamide and perchlozone. We found a wide variation in the MIC of perchlozone from 2 to 64 mg/L, correlating with the overall resistance profile: the MIC was higher for MDR and pre-XDR isolates. The cross-resistance between the ethionamide and the perchlozone was driven by mutations in ethA gene encoding monooxygenase responsible for activation of both drugs. Presumably susceptible to perchlozone wild-type strains had MICs ranged 2–4 mg/L, and the breakpoint estimated to be at 4 or 8 mg/L. In conclusion, susceptibility to perchlozone retained for a part of MDR strains, as does suceptibility to ethionamide, providing the possibility of therapy for such cases based on phenotypic or molecular analysis.
Towards Sustainable Virtual Reality: Gathering Design Guidelines for Intuitive Authoring Tools
Authors: Chamusca Iolanda Lima , Ferreira Cristiano Vasconcellos , Murari Thiago Barros , Apolinário Jr. Antonio Lopes , Winkler Ingrid
Published: January 2023

Virtual reality experiences are frequently created using game engines, yet they are not simple for novices and unskilled professionals who don’t have programming and 3D modeling skills. Concurrently, there is a knowledge gap in software project design for intuitive virtual reality authoring tools, which were supposed to be easier to use. This work compiles design guidelines derived from a systematic literature review to contribute in the development of more intuitive virtual reality authoring tools. We searched the Scopus and Web of Science databases for works published between 2018 and 2021 and discovered 14 papers. We compiled 14 requirement and feature design guidelines, such as Visual Programming, Immersive Authoring, Reutilization, Sharing and Collaboration, Metaphors, and Movement Freedom, among others. The collected guidelines have the potential to either guide the development of new authoring tools or to evaluate the intuitiveness of existing tools. Furthermore, they can also support the development of the metaverse, since virtual content creation is one of its bases.
Model Teori Fraud Diamond mempengaruhi Financial Statement Fraud dimoderasi oleh Innovation Strategy
Authors: Viona Angelina  , Budi Chandra
Published: January 2023

Penelitian ini bertujuan untuk meneliti pengaruh fraud diamond terhadap financial statement fraud dan peran dari innovation strategy dalam memoderasi pengaruh fraud diamond terhadap financial statement fraud. Penelitian dilakukan pada perusahaan yang terdaftar dalam Bursa Efek Indonesia menggunakan teknik purposive sampling, adapun alat analisis yang digunakan adalah analisis regresi logistik dan analisis regresi moderasi. Sampel didapatkan dari 89 perusahaan yang terdaftar pada tahun 2017-2021. Hasil penelitian menunjukkan bahwa komponen dari fraud diamond yang berpengaruh signifikan hanya pada variabel DER, adapun hasil penelitian terbukti bahwa innovation strategy memoderasi pengaruh antara fraud diamond terhadap financial statement fraud.
Categorization of the Higher Attestation Commission List and its place in the national system for evaluating the effectiveness of research and development
Authors:   Russian Research Institute of Health of the Ministry of Health of the Russian Federation, Kurakova N. G. , Tsvetkova L. A. ,   Russian Research Institute of Health of the Ministry of Health of the Russian Federation
Published: January 2023

In 2022, Western countries imposed sanctions on the Russian scientific community, giving grounds to overestimate the paradigm of building an open global scientific system, proclaimed in Europe after the end of the Cold War. The main refrain of the new stage is the strict regulation of European values and transatlantic interests in the security of communications with Russia. The growing relationship between foreign policy and security policy marks a departure from the principles of scientific internationalism, therefore, a National System for evaluating the Effectiveness of scientific research and Development is being created in the Russian Federation. The methodology of creating a sovereign system and the principles of forming a national “white list” of journals and/or scientific publishers, publications in which are taken into account when evaluating the activities of national organizations, collectives or individual scientists, are considered. In order to increase the strictness of the selection of journals of the list of Higher Attestation Commission and the transparency of its replenishment procedures, the Ministry of Education and Science of Russia has developed a Methodology for ranking journals of the list of Higher Attestation Commission. Scientometric indicators are listed, on the basis of which an integral indicator of the “quality of the journal” is calculated for each scientific specialty. The lists of peer-reviewed scientific journals are presented, in which the main scientific results of dissertations for the degree of candidate of science, for the degree of doctor of science, should be published, classified as K1, K2 and K3 in the scientific specialty 14.02.03 – Public health and healthcare (medical sciences).
Problems of medical support for persons over working age (by the example of the Republic of Tatarstan)
Authors:   N. A. Semashko National Research Institute of Public Health., Bakirova E. A.
Published: January 2023

Currently, most countries are showing a demographic trend characterized by an increase in the number of older people. In Russia, there is also a significant aging of the population, in connection with which, the number of people older than working age seeking medical care is growing every year. At the same time, the need is growing not only for treatment and rehabilitation, but also for the prevention of diseases, the implementation of active longevity programs. All this emphasizes the relevance and necessity of high-quality and sufficient medical support for this category of people. Purpose: to study the features of medical support for people older than working age on the example of the Republic of Tatarstan. Materials and methods: the data of official statistics, including those of the Ministry of Health of the Republic of Tatarstan, were used in the work. Analytical, statistical, mathematical research methods were used. Findings: To create optimal resource provision in the provision of medical care to people older than working age, it is necessary to: introduce new indicators of the state of health, increase the number of geriatricians, increase the number of geriatric beds, not reduce therapeutic beds, constantly increase the coverage of preventive medical examinations, medical examinations of people older than working age age, based on their share in the population structure (at least 25%).
Natural intelligence in a counterattack against artificial intelligence (a polemical response to “How to Create a Mind” by Ray Kurzweil)
Authors:   Lobachevsky State University of Nizhny Novgorod, Fatenkov Aleksey N.
Published: January 2023

By turning to geometric metaphors, the author defends the naturally based intelligence and – in the context of analysing Ray Kurzweil’s conception – criticises the artificial in­telligence. The focus is on the ability of man and machine to solve the so-called unsolv­able problems. This issue is discussed in conjunction with the issues of hierarchy, homo­geneity and heterogeneity, contradiction and analogy, meaning and information. Argu­ments are given to support the following ideas: 1) digital technologies do not overcome the fundamental limitations of analogue technologies, thus AI capabilities are also ir­reparably limited; 2) the natural intelligence works in an original way (not by analogy), so there can be no insoluble theoretical problems for it; 3) in a healthy human brain, there is neither excess nor deficiency, it does not need artificial improvement; 4) incomplete actualisation of the brain potential is not a weakness, but a strength and special feature of the human mind; 5) the theory of artificial intelligence is characterised by excessive re­ductionism and fetishization of speed.
FusionPDB: a knowledgebase of human Fusion Proteins
Authors: Kumar Himansu , Tang Lin-Ya , Yang Chengyuan , Kim Pora
Published: January 2023

Tumorigenic functions due to the formation of fusion genes were targeted for cancer therapeutics (i.e., kinase inhibitors). However, many fusion proteins are still awaiting being targeted for therapeutics in diverse cellular working mechanisms. Due to the lack of whole fusion protein sequences and whole 3D structures of the fusion proteins, it was hard to develop novel therapeutic approaches. To fill these critical gaps, we developed a new computational pipeline and a resource of human fusion proteins named FusionPDB, available at https://compbio.uth.edu/FusionPDB. FusionPDB provides ~ 43K fusion protein sequences (of 14.7K in-frame fusion genes, Level 1), 2300 + 1267 fusion protein 3D structures (of 2300 recurrent + 266 manually curated in-frame fusion genes, Level 2), and virtual screening results of 1267 fusion proteins (of 266 manually curated in-frame fusion genes, Level 3). FusionPDB is the only resource providing whole 3D structures of fusion proteins and comprehensive knowledge of human fusion proteins. It will be regularly updated until covering all human fusion proteins in the future.
Wave function matching for the quantum many-body problem
Authors: Lee Dean , Elhatisari Serdar , Bovermann Lukas , Epelbaum Evgeny , Frame Dillon , Hildenbrand Fabian , Kim Myungkuk , Kim Youngman , Krebs Hermann , Lähde Timo , Li Ning , Lu Bing-Nan , Ma Yuanzhuo , Meissner Ulf-G. , Rupak Gautam , Shen Shihang , Song Young-Ho , Stellin Gianluca
Published: January 2023

We introduce a new approach for solving quantum many-body systems called wave function matching. Wave function matching transforms the interaction between particles so that the wave functions at short distances match that of an easily computable interaction. This allows for calculations of systems that would otherwise be impossible due to problems such as Monte Carlo sign cancellations. We apply the method to lattice Monte Carlo simulations of light nuclei, medium-mass nuclei, neutron matter, and nuclear matter. We use interactions at next-to-next-to-next-to-leading order in the framework of chiral effective field theory and find good agreement with empirical data. These results are accompanied by new insights on the nuclear interactions that may help to resolve long-standing challenges in accurately reproducing nuclear binding energies, charge radii, and nuclear matter saturation in ab initio calculations.