bluuebunny/crossref_metadata_2025 huggingface dataset:
Retrospective Analysis of Prevalence of High-risk and Low-risk Human Papillomavirus (HPV) Genotypes in Iranian Women During 2013-2016
Authors: Chalabiani Siavash , Khodadad Nazari Mina , Shabani Mahdi , Razavi Davoodi Neda , Sarafnejad Abdolfattah , Amirzargar Ali Akbar
Published: August 2019

Background and objective: Considering the importance of HPV in cancer etiology, awareness of HPV prevalence and frequency of high-risk genotypes could help improve health care system management. We analyzed HPV prevalence in women forms different provinces of Iran that is the largest sample till now. Material and Methods: In this retrospective cross-sectional study, 2969 outpatient and suspicious women aged 17- 78 referred to Noor pathobiology laboratory from 24 provinces of Iran were studies. DNA extraction and PCR were performed on samples and then HPV genotypes were also determined using hybridization kit. Results: HPV DNA was detected in 29.3% of valid liquid-based samples. Among HPV positive cases, 67.2% and 52.0% accounted for high-risk and low-risk HPV subtypes, respectively. In patients with high-risk HPV types, HPV16 was confirmed as predominate type (30.5%) followed by HPV53 (17.3%) and HPV39 (13.3 %). HPV6 was found as the most common low-risk HPV type with 60.6% frequency rate followed by HPV11 (17.9%) and HPV81 (8.6%) in this age group. It was apparent that age group >25 years accounted the highest frequency of HPV positivity. The prevalence of HPV was significantly different among different age groups (p<0.0001). Conclusion: It can be concluded that HPV infection is currently at a considerable high level in Iran. Looking at the high risk and oncogenic HPV subtypes frequency especially in younger age groups, a concern could be noticed about HPV relevant cancers which can be prevented by commercial and approved HPV vaccines.
Cytotoxic Effect of Two Novel Platinum (II) Complexes on Breast Cancer: An in Vitro Study
Authors: Akbarzadeh Samad , Ebrahimi Fatemeh , Faghih Zeinab , Movahed Ali , Faghih Zahra
Published: August 2019

Background: With 1.36 million new cases in worldwide each year, breast cancer (BC) is the most common malignancy in the female. Among numerous chemotherapy drugs which are widely used for cancer therapy, platinum compounds are the most persuasive ones although challenges remain with the clinical use of them due to their side effects as well as intrinsic and acquired resistance. In the attempt to combat drug resistance, reduce cytotoxic side effects or find the drug for particular forms of cancer, over the years, thousands of other platinum (Pt) compounds i.e. carboplatin and oxaliplatin have been developed.Material and Methods: In this regard, we previously described the synthesis of some new platinum (II) derivatives with potential anti-cancer activities against BC. Here, we chose two of the best platinum(II) compounds, 3b and 2a, to further evaluate their cytotoxic activities against human BC cell lines, SKBR3, MCF-7, MDA-MB-231, and MBA-MB-468, with different molecular subtypes using a colorimetric MTT cytotoxic assay. Their cytotoxic activities were compared to cis-platin as a positive control. Results: Our result showed that both compounds had better cytotoxic effect against BC cell lines than cis-platin in particular in the case of triple-negative subtype.Conclusion: These results suggest these compounds as potentially valuable agents for the treatment of breast cancer patients.
Immunostimulatory and Anti-inflammatory Effect of Ganoderma Lucidum on Breast Cancer Patients
Authors: AK. Mohammed Ali Nidhal , Abdulkareem Saeed Hakar , T. Othman Ramadhan
Published: August 2019

Background: Breast cancer (BC) is the most common cancer among women. A key factor in tumour development is the evasion of immune detection, therefore; search for alternative medicines with the ability to improve the function of the immune system and targets tumours cells has received growing interest. Ganoderma lucidum (GL) has been demonstrated to possess anti-tumour and immunomodulatory activities. Little is known about the immunomodulatory effect of GL on BC patients when used with chemotherapeutic agents. We aim to investigate the level of immune biomarkers; interferon-γ (IFN-γ), tumour necrotic factor-α (TNF-α), interleukin-8 (IL-8) and adiponectin in these patients.Material and Methods: Forty female patients with BC were included and divided equally into two groups: Group 1 received chemotherapy alone and Group 2 received chemotherapy plus GL capsules (1000 mg twice daily). Blood samples were obtained from all patients before and after 4 cycles of chemotherapy. These samples were analysed to identify the levels of IFN-γ, TNF-α, IL-8, and adiponectin.Results: After the treatment period, there was the significant increase in the level of IFN-γ (P=0.0024) and a significant decrease in the mean serum levels of TNF-α (P=0.0004) and IL-8 (P=0.019) in patients treated with concurrent GL and chemotherapy. A non-significant difference was found between pre and post-treatment in the mean serum levels of TNF-α, IFN-γ, and IL-8 in patients receiving chemotherapy only. The mean serum levels of adiponectin in both groups did not show any significant difference when compared to pre-treatment levels. Conclusion: The present study showed that the use of GL in-combination with chemotherapy could have immune stimulatory, anti-inflammatory and anti-metastatic activity that can enhance the therapeutic responsiveness of BC patients to chemotherapy and improve their quality of life during treatment. More research is needed to confirm these results. In addition, clinical evaluation of benefit and outcome are ongoing
Correlation of Peritumoral Edema and Microvessel Density with Tissue Expression of VEGF, Semaphorins 3A and 3C in Patients with Meningioma
Authors: Salimi-Sotoodeh Mehdi , Saffarian Arash , Taghipour Mousa , Dehghanian Amir-Reza , Chenari Nooshafarin , Ghaderi Abbas , Razmkhah Mahboobeh
Published: August 2019

Background: Several angiogenic factors correlate with angiogenesis in meningioma while their exact role is yet to be identified. Semaphorins are described with a variety of physiological functions including angiogenesis and migration of neural crest cells. Objective: We aimed to determine the correlation of semaphorin 3A, 3C (Sema 3A and 3C) and vascular endothelial growth factor (VEGF) expression with microvessel density (MVD) and peritumoral brain edema (PTBE) in meningioma.Methods: In this study 21 patients with grade I meningioma were included. PTBE was measured on axial and coronal brain MRI. Tissue expression of semaphorin 3A, 3C and VEGF were determined using quantitative real-time PCR (qRT-PCR). Result: We found that mean vascular density and tumor edema index were negatively associated with tissue expression of semaphorin 3A and 3C, respectively (p=0.029 and p=0.048). VEGF did not show statistically significant correlation with tumor characteristics studied (p> 0.05). We also found that the mean vascular density of the menigiomas was positively associated with intra operative blood loss (r=0.503, p=0.010). Conclusion: Our data indicates an inverse correlation of Sema3A and Sema3C with vascular density and peritumoral edema, respectively, while no correlation could be shown for VEGF. Thus, Sema3A and 3C may be identified as appropriate inhibitors of pathological angiogenesis in human meningioma. However, confirmation of this finding in a larger dataset is warranted.
Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma: A Focus on Tumor-Infiltrating Lymphocytes
Authors: Norouzian Marzieh , Balouchi-Anaraki Sima
Published: August 2019

For more progress in head and neck squamous cell carcinoma (HNSCC) immuno-oncology, further understanding of interactions between tumor and immune system as well as factors in the tumor microenvironment is required. HNSCC is seriously infiltrated by lymphocytes but is known to be highly immunosuppressive. The aim of this review is to highlight the complexity of tumor microenvironment and tumor- immune cells interaction in the HNSCC, in order to improve understanding of tumorigenesis and disease progression in HNSCC patient and to provide valuable information about prognostic markers. The main goal of this review is to discuss the role of the tumor infiltrating lymphocytes in tumor progression, their cross-talk with other components of the tumor microenvironment as well as their roles in carcinogenesis, metastasis process, treatment, and prognosis in head and neck squamous cell carcinomas.
GSTM1 and GSTT1 Polymorphisms and Susceptibility to Acute Myeloid Leukemia: A Case-control Study of the Sudanese Population
Authors: Babekir Ebtihal Ahmed , Abdelateif Nour Mahmoud , Adelrahim Saadia Osman , Hassan Rosline , Ibrahim Ibrahim Khider
Published: August 2019

Background: Glutathione S-transferase (GST) enzyme levels are associated with risk of many types of cancers, including hematological malignancies. In this study we here aimed to investigate the relationship between GSTM1 and GSTT1 polymorphisms and the risk of AML. Conflicts in the published results and the absence of similar in-depth studies in Sudan prompted us to perform the present case-control study to determine the frequency of GSTM1 and GSTT1 polymorphisms in AML patients and their possible association with AML in a Sudanese population.Materials and Methods: A total of 40 patients with AML and 40 control subjects were enrolled in this study. Blood samples were collected from all patients in EDTA containing tubes. Genomic DNA was extracted from all blood samples using salting out method. Genotyping for detection of GSTM1, and GSTT1 polymorphisms was performed for both patients and controls using a multiplex PCR. Results: We reported that there is an association between the GSTM1 null genotype and AML risk (OR= 2.7, 95% CI= 1.2-6.04; P.value = 0.012), the GSTT1 null genotype appeared also to have an influence in the development of AML (OR= 4.93, 95% CI= 1.6-15.07; P.value = 0.005).Conclusion: These findings indicate that genetic variants of GSTM1 and GSTT1 genes may increase individual susceptibility to AML.
Surveying Mutation of FLT3 Genes in Children with Acute Leukemia
Authors: Sheikhi Maryam , Zaker Farhad , Javadi Gholamreza , Hashemi Mehrdad , Razmkhah Farnaz , Movafagh Abolfazl
Published: August 2019

Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrolled proliferation of leukemic cells and a bad prognosis. The present study is aimed at implementing molecular tests to diagnose and screen the mutations in acute leukemia patients. Methodology: Totally, 91 children with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) were examined as to flt3 mutation, internal tandem duplication (ITD) mutation, and point mutation in exon 17 (e17). ITD mutation in flt3 receptor was carried out in exon 12&12 and intron 11. As to point mutation in e17, PCR products of the subjects after PCR on genomic DNA of them were examined using restriction enzyme (ECORV) and restriction fragment length polymorphism (RFLP). As to ITD positive, sequencing method was used. Findings: ITD mutation was observed in seven (7.7%) of acute leukemia patients and two (2.2%) patients were diagnosed with point mutation D835. Distribution in different subgroups of FAB was not identical. Conclusion: FLT3 mutation was highly prevalent in children with acute leukemia. Therefore, molecular diagnosis of these mutation, regardless of FAB categorization and before initiation of intervention, can be used to make better decision about therapeutic protocol.
Epidemiological and Retrospective Survey of Pancreatic Cancer in Ilam City During a 10 Years Period (From 1385 Till 1394)
Authors: Zarei Hamed , Tavan Hamed
Published: August 2019

Background: one of the most killing cancers globally and the fourth most relevant cancer, the pancreatic cancer has a great numbers of victims every tear, therefore, the goal of this study was to investigate the rate of incidence among residents of ilam in time span of 10 years, from 1385 till 1394.Materials and Methods: this is a retrospective study during 1385 till 1394 in Ilam city. Our source of patients was the afflicted patients. The sample size and the statistical society of research were determined based on census. The research materials included of two types first included the demographic information of patients (age, gender, tumor type, level of education, residency, smoking and lipid profile) and the second part was some information about the pancreatic cancer (anatomical site, pathologic findings and lipid profile).using SPSS version 19, the data was analyzed. Results: the statistical society included 25 individuals afflicted with pancreatic cancer in which the most prevalent age group was men older than 70 years (60 years) (31.3%). Furthermore, as time went on, the number of new cases increased. Conclusion: the risk factors for occurring the cancer were the age group greater than 70 years, being male, lower educational situation, unemployment, living in an urban areas, smoking, hereditary, hyperlipidemia (LDL, TG, CHOL) and finding tumor in middle third of pancreatic (because of existing helicobacter pylori virus and impropriate diet). Being able to identify endangered people, one could begin treating patients and thereby, saving time, cost and increasing the rate of survivors.
mRNA Biomarkers for Detection of Oral Squamous Cell Cancer
Authors: Rashid Fatemeh , Naji Tahereh , Mohamadnia Abdolreza , Bahrami Naghmeh
Published: August 2019

Objectives: Cancer is one of the main causes of death in the world. Changes in the expression of CK19 and CEA genes in peripheral blood of OSCC patients were examined for early diagnosis. Methodology: The participants were 36 patients and 36 normal individuals. CK19 and CEA of blood serum were measured through Real-Time PCR. The relationship of the biomarkers with tumor staging and cancer development was examined. Results: Comparison of the two groups of participants using t-test indicated no significant difference in terms of mean age. CK19 marker was positive in 19 participants of the patients group (n=36), which meant the sensitivity of the marker was 53%. In addition, the marker was positive in eight participants of the normal group (n=36). CEA marker was positive in 26 participants of the patients group (n=36), which meant the sensitivity of the marker was 72%. Moreover, the marker was positive in 11 participants in the normal group (n=36). Conclusion: In general, the study introduced a screening test for early diagnosis of OSCC. To have evidences with more reliability, future studies should be carried out with larger sample groups.
Clinical Outcome and Survival of Post-molar GTN Versus Non-molar GTN Patients
Authors: Oranratanaphan Shina , Lertkhachonsuk Ruangsak
Published: August 2019

Background: Gestational trophoblastic neoplasia (GTN) can derive either from molar or non-molar pregnancy. Our primary objective is to compare clinical presentation and outcome of treatment of non-molar and post-molar GTN. Our secondary outcome is to evaluate and compare the prognostic factors of non-molar GTN compare to post-molar GTN in subgroup classification of GTN patients by stage and by low-risk and high-risk groups.Methods: Retrospective chart review of GTN patients treated from 2007 to 2016 was done. General characteristics, clinical data, treatment options and treatment outcomes were collected. The cases with missing significant data were excluded. Statistics analysis of the data was performed with SPSS version 22.0. Mean, mode, median and percent were used to present the data. Student t-test, Mann Whitney-U test and Kaplan Meier were used to analyze the data. The results were presented in Tables or graphs where appropriate. Results: Total of 71 GTN patients were recruited into the study. Fifty-one patients were post-molar GTN and 20 were non-molar GTN patients. The mean age of the patients was not different (p=0.25). Median duration from previous pregnancy and time to achieve remission were longer in non-molar GTN (292 days vs. 42 days and 163 vs. 64 days, respectively). Mortality rate of the non-molar GTN is higher that of the post-molar GTN (15% vs. 1.9%). Comparison of stage to stage showed no differences between the post-molar and the non-molar GTN. According to previous pregnancy type, post-abortion had higher resistant to treatment rate than post-term delivery.Conclusion: Non-molar GTN is different form post-molar GTN in several aspects, such as the duration from previous pregnancy, stage and score at diagnosis, treatment resistance and mortality rate. Comparison between the non-molar and post-molar GTN stage by stage and risk scores could not identify the difference between the two groups.
Knowledge, Attitudes and Practice of Cervical Cancer Prevention among Student Health Professionals in Nigeria
Authors: Anene-Okeke Chigozie Gloria , Aluh Deborah O , Okorie Uzoamaka Henrietta
Published: August 2019

Background: Cervical cancer is the second most commonly diagnosed gynecological cancer affecting women worldwide. It is a preventable disease but still remains a leading cause of cancer deaths in developing countries like Nigeria despite the availability of preventive strategies. Undergraduate pharmacy and medical students are future health care providers who can help raise awareness and improve the knowledge of the public towards cervical cancer, its screening, prevention and treatment. The study sought to assess the knowledge, attitudes and practice of cervical cancer screening and prevention.

Materials and methods: This is a cross sectional survey using questionnaire conducted in the University of Nigeria and Nnamdi Azikiwe University both in South-eastern Nigeria. Participants were conveniently sampled and the self-administered questionnaire was given to 335 consenting female pharmacy and medicine undergraduate students.

Results: 335 out of the 350 undergraduate students approached responded (95.7 % response rate). The result of the study shows that the students generally had a good level of awareness of cervical cancer. The students surveyed had a mean knowledge score of 75.9062±20.265. More than a third (36.1%, n = 214) of the students had a negative attitude towards cervical cancer. Only about one in eight students reported to have had a pap smear (12.54%, n = 42).

Conclusion: The students generally had a good awareness and knowledge of cervical cancer which was not translated into practice. There is a need to include public health principles into the curriculum of Pharmacy and Medical schools in Nigeria since they are future health advisors.
ThinPrep Pap Test for Diagnosis of Cervical Cancer in Early Stages
Authors: Sabour Siamak , Abbasnezhad Ommolbanin , Dastranj Tabrizi Ali , Vahedi Amir , Mostafidi Elmira
Published: August 2019

Background: Cervical cancer is one of the world’s deadliest forms of cancer and Pap smear is the most popular screening test for diagnosis in early stages. The aim of our study was to assess potential screening rule of ThinPrep Pap test. Methods: In this cross sectional, study Cervical samples were collected from all women who referred to a pathology center for Papanicolaou test and all samples were prepared with ThinPrep process. To assess validity, biopsy was selected as gold standard. 131 women who had ThinPrep Pap test and biopsy were considered for the analysis. The participants were selected purposeful. Three thresholds were used to define test positivity: 1) Atypical squamous cells of undetermined significance (Asc-us) 2) Low grade squamous intraepithelial lesion (LSIL) 3) High grade squamous intraepithelial lesion (HSIL) and worse. Inter and intra observer reliability were evaluated using kappa (simple and weighted) as well as Fleiss kappa and validity were assessed by the well-known validity estimates for qualitative variables. Results: Intra observer reliability was moderate for pathologists with low and moderate experience (kappa was 0.44 and 0.46 respectively) and was good for experienced pathologist [kappa (WK) = 0.64]; however, inter observer reliability was poor (Fliess kappa=0.12). For diagnosis of ASCUS and worse, the sensitivity was 96.3% and for diagnosis of HSIL and worse the sensitivity and specificity were 86.6% and 95.1%, respectively.Conclusion: ThinPrep pap is an acceptable screening test for diagnosis of cervical cancer in early stages. However, experience and specialty have effect on reliability’s results.
LAYANAN INFORMASI MENINGKATKAN PERCAYA DIRI SISWA DALAM MENGEMUKAKAN PENDAPAT DI MAN 3 BANJARMASIN
Authors: Mahdalena Mahdalena
Published: August 2019

This research is motivated by the lack of confidence of students in expressing opinions in the school environment or society. Confidence in expressing opinions makes students active in the teaching and learning process, daring to express their opinions, dare to reject something that is considered incorrect, not hesitating in attitude. By increasing students' confidence in expressing their opinions, it is expected that students can become individuals who are confident in their abilities.The method used in this study is a quantitative method using the Pre-Expansion Designs design in the form of a Pretest-Posttest group. this design to find out the results of the treatment more accurately, in this study conducted 2 observations (measurements), namely comparing the conditions before and after being treated.The results of the research obtained by the Pre-test Results of the sample showed that the average percentage of self-confidence before joining the Information Service increased students' self-confidence by 35.64% which was included in the medium category. After getting the treatment experience an increase and fall into the medium category. The post test results showed that the average percentage of self-confidence after taking treatment in the form of information services increased students' confidence in expressing opinions by 64.04%, which was included in the High category.The conclusion of this study is that there is a positive change in the form of increasing students' self-confidence after being treated with information services in expressing their opinions.
SISTEM INFORMASI DATA AKADEMIK SEKOLAH PADA MTS. AL – FURQON BANJARMASIN
Authors: Farida Muthia , Agustini Dian
Published: August 2019

Penelitian ini bertujuan untuk membuat sebuah sistem informasi data akademik yang dapat mempermudah pihak sekolah dalam mengelola data akademik sekolah serta mempermudah orang tua murid dalam memantau tumbuh kembang anak disekolah dengan tahapan metode penelitian : 1. Tahap pengumpulan data yaitu : a) wawancara dengan berkomunikasi secara langsung dengan bagian kepala Sekolah, guru serta tata usaha, b) observasi atau pengamatan langsung, c) studi literatur dengan cara mereview jurnal-jurnal ilmiah, buku atau berbagai sumber yan terkait dengan penelitian yang akan dibuat. 2. Analisi Kebutuhan Sistem. 3. Tahap desain sistem yang  menetukan proses dan data yang diperlukan oleh sistem baru. Sistem Informasi data akademik ini menggunakan metode pengujian black box dengan keberhasilan pengujian sistem yang dibuat. Kata  Kunci  :  Blackbox, Data Akademik, Sistem Informasi
ANALISIS PERANCANGAN APLIKASI PUSAT INFORMASI (E-PusIn) BERBASIS WEB : STUDI KASUS KAMPUS UNISKA BANJARMASIN
Authors: Mahalisa Galih
Published: August 2019

Sistem informasi merupakan sistem yang mencakup sejumlah komponen (manusia, komputer, teknologi informasi, dan prosedur kerja), ada sesuatu yang diproses (data menjadi informasi), dan dimaksudkan untuk mencapai suatu sasaran atau tujuan. Permasalahan yang terjadi adalah ketidaktahuan pengunjung dalam mencari lokasi ruangan atau denah kampus karena belum tersedianya  fasilitas / stand sebagai pusat informasi kampus yang terletak di tengah lobby gedung utama. Berdasarkan hasil analisa dengan melakukan observasi pada pada hari dan jam kerja sekitar 80% pengujung yang pertama kali datang ke uniska, akan bertanya kepada orang sekitar yang ada di lobby, 15% tamu menunggu di lobby yang kemudian dijemput oleh yang berkepentingan, dan sisanya mencari tahu sendiri dengan cara berkeliling kampus. Metode yang digunakan berdasarkan studi kasus, untuk pengujian perangkat lunak  menggunakan standard ISO 9126. Hasil pengujian dan analisa yang ddidapatkan dari 15 orang responden, maka hasil pengujian functionality menyatakan 88% termasuk skor baik untuk pengelolaan fungsi-fungsi pada aplikasi, hasil uji usability menyatakan 68% cukup baik untuk pengguna dalam menggunakan sistem, dan dalam hal maintainability pada pengujian aplikasi ini sangat bagus dalam hal pengembangan aplikasi yang lebih baik Kata Kunci : sistem, informasi, kampus, lobby, aplikasi, pengujung, tamu
O ESTUDO GEOGRÁFICO DO USO DO NOME SOCIAL NO EXAME NACIONAL DO ENSINO MÉDIO: A ENTRADA DA POPULAÇÃO TRANS NO ENSINO SUPERIOR
Authors: França Rebecka de , Viana João Paulo Teixeira , Gomes Jeam Claude de Souza , Pessoa Fé Maria do Socorro , Miranda Levi Rodrigues de
Published: September 2019

O presente trabalho traz à tona uma pesquisa de grande importância para o âmbito da geografia que é o estudo da diversidade social no âmbito da ciência geográfica, estudar o gênero e suas particularidades é de grande valia, pois consegue compreender as relações sociais. O objetivo central é analisar a importância da utilização do nome social no Exame Nacional do Ensino Médio (ENEM) com relação aos percentuais de adereção a essa nova conquista. O trabalho se justifica mediante a necessidade de ter estudos voltados para a área LGBT’s dentro da ciência geográfica, a mesma por ser um amplo campo de estudo multidisciplinar e que conseguem percorrer por diversos vieses. Além disso, é notório que estudo como esses são escassos na academia, sendo assim, uma maior contribuição para a temática LGBT’s no Brasil. A pesquisa faz uso de pesquisas referenciais e bibliográficas com relação a conquista por parte das travestis e transexuais no direito da utilização do nome social em diversos processos seletivos como é o caso do Enem, bem como em artigos e postulado concernentes a temática, uma vez que existe poucos estudos na área, bem como escassos artigos e resumos sobre o uso do nome social. O artigo está dividido de forma sequencial e objetiva, onde será possível entender a utilização do nome social na constituição federal, e sua alocação na atualidade, bem como o processo que se deu essa nova adequação no Exame Nacional do Ensino Médio. O uso do nome social é um importante direito que as travestis e transexuais conseguiram, um direito constitucional da cidadania.
BIÓLOGOS NA REDE: UTILIZAÇÃO DA TECNOLOGIA VIRTUAL PARA COMUNICAÇÃO E DIVULGAÇÃO DAS CIÊNCIAS BIOLÓGICAS
Authors: Braga Dan Vítor Vieira , Lima Luan Filiph Damascena , Ribeiro Ana Jessica
Published: September 2019

As estratégias de comunicação sofisticam-se e ampliam cada vez mais suas funcionalidades, desenvolvendo continuadamente novas ferramentas de compartilhamento de informação cada vez mais populares entre os adolescentes. As redes sociais podem ser consideradas grandes aliadas na produção e divulgação de conteúdo. Os grupos de debate acerca de pesquisa e ciência vêm ganhando espaço na internet, tendo como público-alvo tanto pesquisadores, como também leigos que se interessam por temas ligados à ciência. Assim, este trabalho objetivou disseminar conhecimentos e atividades desenvolvidas pelos alunos do curso de licenciatura em Ciências Biológicas da FACHUSC, bem como da profissão Biólogo, de forma a desmistificar os preconceitos sociais relacionados a estes dois temas. Foram desenvolvidas páginas no Facebook® e Instagran®, onde, semanalmente, eram postadas notícias do cotidiano da biologia e atividades desenvolvidas pelos alunos do curso. O foco das matérias de divulgação foram as atividades extracurriculares tais como: seminários; aulas práticas de laboratório ou campo; gincanas; trabalhos sociais; viagens; intercâmbios, etc. O presente trabalho obteve forte adesão do corpo discente do curso, apesar da participação ser voluntária e não contabilizar nenhuma pontuação extra em avaliações. Observou-se também uma grande aceitação do público em geral, principalmente alunos do Ensino Médio de escolas públicas. Isto se deve, provavelmente, por este público fazer uso mais intenso das redes sociais e de ambientes virtuais de aprendizagem. Isso resultou em melhoria da interatividade dos alunos do curso de Ciências Biológicas, como também na sua participação nas atividades extracurriculares. Além desta variável, foram analisadas também a participação nos debates vinculados às postagens, percebendo-se um significativo compartilhamento e interação dos usuários com as postagens. Fato corroborado ao se analisar o número de “curtidas”, compartilhamentos do conteúdo, inserção de comentários e de respostas a comentários de terceiros nos vídeos ou imagens postadas. Ao final de um ano de trabalho, houve um aumento nas inscrições para ingresso no curso Licenciatura em Ciências Biológicas da FACHUSC, podendo isto está diretamente relacionado com o marketing positivo intensamente praticado via redes sociais. Conclui-se que o investimento em divulgação de conteúdos através das redes sociais contribuiu para um aumento da produtividade dos alunos e dos professores vinculados ao curso, como também no interesse dos alunos do Ensino Médio na profissão Biólogo, desfazendo pré-conceitos locais com relação a profissão, tornando-se uma ferramenta eficaz para encurtar a distância entre a sociedade e a instituição de Ensino Superior.
A ARTE PRESENTE NA GEOGRAFIA: UM ESTUDO ACERCA DO DIÁLOGO ENTRE A CIÊNCIA E A EXPRESSÃO ARTÍSTICA NO CONTEXTO DO PROGRAMA DESPERTANDO VOCAÇÕES PARA LICENCIATURA
Authors: Bezerra Nielson da Silva , Braga Clezia Aquino de , Barbosa Jhonata Wesley Gomes
Published: September 2019

Nossa pesquisa busca compreender as relações e diálogos que existem entre a Geografia e as Artes. Acreditamos que esta busca contribua para a compreensão do fazer docente na Geografia, considerando que aproximar-se do conhecimento através do diálogo entre as artes e a ciência é uma escolha metodológica que rompe com o conceito tradicional “do científico” e convoca nossos sentimentos, nossa intuição e expressão para um diálogo com a razão. Nosso estudo se debruça sobre as relações existentes entre Geografia e Arte, de modo a produzir estratégias didáticas que fortaleçam a cooperação desenvolvida pelo PDVL e o despertar do interesse para a carreira docente em Geografia. Nossa pesquisa utiliza como referência metodológica a pesquisa qualitativa de cunho participante, apoiada no aprofundamento teórico em torno dos temas Arte, Geografia e Ensino.  Realizamos uma pesquisa-ação numa escola pública parceira. Nosso trabalho estuda as formas de diálogos entre a Expressão Artística e o ensino da Ciência Geográfica, tendo como grande desafio fazer com que o docente e os futuros docentes procurem entender e explorar as possibilidades teóricas e metodológicas presentes nesta intercessão. O diálogo de saberes entre artes e geografia ainda é um grande desafio, mas acreditamos que esse seja o caminho para despertarmos ainda mais o desejo de se aprender até chegar ao ponto de que os estudantes sejam formados para serem cidadãos críticos e atuantes em seu tempo e em sua realidade, de modo a construírem um mundo mais justo e fraterno. Diante dos estudos mobilizados até o momento, entendemos que é necessário fortalecer os instrumentos teóricos e metodológicos que propiciam o diálogo entre Geografia e Artes. Após os estudos teóricos desse primeiro momento, fica clara a importância da expressão artística no processo educacional e principalmente na relação do ensino da Geografia.
Rebleeding drives poor outcome in aneurysmal subarachnoid hemorrhage independent of delayed cerebral ischemia: a propensity-score matched cohort study
Authors: Lu Victor M. , Graffeo Christopher S. , Perry Avital , Carlstrom Lucas P. , Rangel-Castilla Leonardo , Lanzino Giuseppe , Brinjikji Waleed , Wijdicks Eelco F. M. , Rabinstein Alejandro A.
Published: August 2019

OBJECTIVE

Delayed cerebral ischemia (DCI) and aneurysm rebleeding contribute to morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH); however, the relationship between their impacts on overall functional outcome is incompletely understood.

METHODS

The authors conducted a cohort study of all aSAH during the study period from 2001 to 2016. Primary end points were overall functional outcome and ischemic aSAH sequelae, defined as delayed cerebral ischemia (DCI), DCI with infarction, symptomatic vasospasm (SV), and global cerebral edema (GCE). Outcomes were compared between the rebleed and nonrebleed cohorts overall and after propensity-score matching (PSM) for risk factors and treatment modality. Univariate and multivariate ordered logistic regression analyses for functional outcomes were performed in the PSM cohort to identify predictors of poor outcome.

RESULTS

Four hundred fifty-five aSAH cases admitted within 24 hours of aneurysm rupture were included, of which 411 (90%) experienced initial aneurysm ruptures only, while 44 (10%) had clinically confirmed rebleeding. In the overall cohort, rebleeding was associated with significantly worse functional outcome, longer intensive care unit length of stay (LOS), and GCE (all p < 0.01); treatment modality, overall LOS, DCI, DCI with infarction, and SV were nonsignificant. In the PSM analysis of 43 matched rebleed and 43 matched nonrebleed cases, only poor functional outcome and GCE remained significantly associated with rebleeding (p < 0.01 and p = 0.02, respectively). Multivariate regression identified that both rebleeding (HR 21.5, p < 0.01) and DCI (HR 10.1, p = 0.01) independently predicted poor functional outcome.

CONCLUSIONS

Rebleeding and DCI after aSAH are highly morbid and potentially deadly events after aSAH, which appear to have independent negative impacts on overall functional outcome. Early rebleeding did not significantly affect the risk of delayed ischemic complications.
Budidaya Ayam-Ikan Terintegrasi Dalam Pembangunan Ekonomi Masyarakat Desa Nyogan Kecamatan Mestong
Authors: Muhammad  , Syarifuddin Hutwan , Mairizal Mairizal
Published: August 2019

Abstract

The aim of the service activity was to develop the economy of Nyoga Community through the cultivation of integrated fish broiler.Due to the successfulness of the previous service program in year 2017 concerning the cultivation of Tilafia and catfish with farmer group (Kelompok Usaha Bersama (KUBE)) Mina Jaya dan Harapan Makmur in Nyogan village, the next program was to tried to apply the cultivation program of integrated fish and broiler by participation method from all of members of KUBE. Like previous program, the method was to involve all the group member of KUBE. Group member prepared the chicken pen above the fish pond and service team from University of Jambi granted the breed of fish and chicken. The result showed the good achievement with the increase of community interest of the KUBE to self-financingly build more unit of box fish nets

Keyword : Nyogan, catfish, tilafia, integrated system, broiler
Analisis Pengaruh Economic Value Added (EVA), Debt To Equity Ratio (DER), Return On Asset (ROA), dan Current Ratio (CR) terhadap Return Saham
Authors: Rois Muhammad , Pandiya Pandiya , Diah K.S Ni Made
Published: August 2019

This study aims to examine the significance of the effects of Economic Value Added, Debt to Equity Ratio, Return on Assets, and Current Ratio To stock againts returns in mining sector companies listed in Indonesia Stock Exchange 2013-2017. This study uses secondary data. The samples in this research are determined by purposive sampling technique. The samples used in this research are 6 (six) mining companies listed on Indonesia Stock Exchange. Testing hypothesis by using regression tool of panel data  supported by software eviews 9. Results of F test of  this research show that Economic Value Added (EVA), Debt to Equity Ratio (DER), Return on Asset (ROA), simultaneously have a significant effect against stock returns on the company. The result of t test shows that the Economic Value Added partially does not have a significant effect on stock return, while the Debt to Equity Ratio, Return on Asset, and Current Ratio have significant effect to stock return on mining companies listed in Indonesia Stock Exchange period 2013-2017.
Uji Coba Proses Pengempukan Daging dengan Ekstrak Daun Pepaya dan Ekstrak Nanas
Authors: Krisnadi Antonius Rizki
Published: September 2019

Papaya leaves and pineapple fruit help the process of natural meat refinement. The aim of the study was to determine meat deflation with papaya leaf extract and pineapple fruit with texture of meat tenderness, aroma of meat specificity after and physical quality of meat before processing. This study uses an experimental method to look for the effect of treatment on others in controlled conditions. Using a sample of 15 expert panelists for the results of meat treatment using the categorization method. The results of the study used papaya leaf extract and pineapple fruit, that soaking for 45 minutes meat (P3) caused a change in the texture of tenderness of the meat, the aroma of the peculiarities of the meat after processing changed with the aroma of papaya leaves and pineapple fruit. While the physical quality of the meat prior to processing, the panelists gave the answer P1, which was soaking for 15 minutes. P2 and P3 in physical quality look pale and not fresh before processing. Suggestions researchers conducted further research on nutrition and water content in meat.
PENGARUH KEMASAN PRODUK DAN RASA TERHADAP MINAT BELI YANG BERDAMPAK PADA KEPUTUSAN PEMBELIAN PELANGGAN MINUMAN ENERGI
Authors: Willy Willy , Nurjanah Siti
Published: August 2019

This study aims to: Know and explain and evaluatethe effect of product packaging and taste on customer buying interests that have an impact on customer buying decisions; and knowing and explaining the influence of buying interest on buying energy drink customers. The variables in this study are product packaging and taste with buying interest as intervining variables and buying decisions as the dependent variable. This study uses a type of quantitative research. The population of this study were respondents who consumed energy drinks. The sample used amounted to 137 respondents using purposive sampling. The results showed that: product packaging and taste had a positive effect on customer buying interest; product packaging forms have a positive effect on customer buying decisions; product taste does not have a positive effect on buying interest and customer buying decisions.
PENGARUH INFLASI, SUKU BUNGA, NILAI TUKAR, DAN PRODUK DOMESTIK BRUTO TERHADAP NILAI PERUSAHAAN
Authors: Dewi Sartika Umi , Siddik Sa’adah , Choiriyah Choiriyah
Published: August 2019

The problem of this study is whether there is the influence of inflation, interest rates, exchange rates and gross domestic product on the value of the company in the textile and garment sub-sector manufacturing companies listed on the Indonesia Stock Exchange. The results of the study concluded, first, inflation has a negative effect, it states that inflation is inversely related to the value of the company with inflation. Second, interest rates, exchange rates and gross domestic product have a positive influence on the value of the company. The third is an increase in the value of the company, so there is also an increase in interest rates, exchange rates and gross domestic product, and vice versa. Third, inflation, interest rates, exchange rates, and gross domestic product partially influence the value of the company in the textile and garment sub-sector manufacturing companies listed on the Indonesia Stock Exchange for the period 2012-2017 simultaneously and have a positive and significant effect on the value of companies in manufacturing companies. Textiles and Garments Registered on the Indonesia Stock Exchange. Fourth, inflation, interest rates, exchange rates, and gross domestic product jointly affect the value of the company in the Textile Subsector and Garment Manufacturing Companies Listed on the Indonesia Stock Exchange.
PENGARUH DISIPLIN, KOMPETENSI KEPRIBADIAN DAN SUPERVISI KEPALA SEKOLAH TERHADAP KINERJA GURU SMP NEGERI DI PALEMBANG
Authors: Astining Putri Nuraida , Seri Herman , Sakdiahwati Sakdiahwati
Published: August 2019

The purpose of the study was to determine the effect of discipline, personality competence and supervision of the principal on the performance of the teachers of the Public Middle School in the Seberang Ulu 1 District of Palembang.The research design uses an associative type. The population in this study were teachers of Public Middle Schools in the Seberang ULU 1 Palembang District, amounting to 305 people. The sampling technique in this study is cluster sampling. The sampling technique uses the Yamane formula to obtain 173 people, the analysis model used uses multiple linear regression methods.The results showed that: 1) There was a significant effect of discipline, personality competence and supervision of principals together on the performance of teachers in the Public Middle School in the Seberang ULU 1 Palembang District. 2) There is a significant effect of discipline, personality competence and supervision of principals partially on the performance of teachers in the Public Middle School in Seberang District ULU 1 Palembang.The implications of this study provide results that principals as leaders must be able to provide examples of discipline to teachers accompanied by communication that can lead to compliance. The principal includes his teacher for personality training to improve knowledge, skills, skills, and attitudes to be able to carry out tasks and positions based on the personality needed by a teacher. Furthermore, the principal needs to master the supervision technique so that he can find out the problems that occur in his school.
Penggunaan Tepung Limbah Roti Dalam Ransum Terhadap Performa Ayam Broiler
Authors: Triani Hera Dwi , Elisia Rini , Siddiq Ibnu Qorma
Published: August 2019

Limbah roti cukup potensial untuk digunakan dalam ransum broiler karena mengandung gross energi yang cukup tinggi (4217 Kkal/kg). Tujuan penelitian ini untuk mengetahui pengaruh pemberian tepung limbah roti sebagai pengganti jagung dalam ransum terhadap performa ayam broiler. Penelitian ini menggunakan broiler berumur sehari atau DOC sebanyak 24 ekor yang dipelihara selama 4 minggu. Pakan terdiri dari jagung, dedak, tepung limbah roti dan konsentrat. Alat yang digunakan seperti : kandang panggung sebanyak 2 petak, tiap petak berukuran 1m x 1m yang berisi 12 ekor broiler dan dilengkapi dengan tempat pakan, tempat minum dan lampu. Penelitian dilakukan secara eksperimen dengan membandingkan dua perlakuan melalui uji T yang terdiri dari 2 perlakuan dari 2 jenis ransum yaitu : ransum J : konsentrat + dedak padi + jagung dan ransum R : konsentrat + dedak padi + tepung limbah roti. Kedua jenis ransum (ransum J dan R) masing-masing diberikan kepada 2 kelompok ayam, masing-masing kelompok terdiri dari 12 ekor ayam. Parameter yang diamati adalah konsumsi ransum, pertambahan bobot badan, konversi ransum dan mortalitas. Hasil penelitian menunjukan terdapat pengaruh yang nyata lebih tinggi (P<0,05) terhadap pertambahan bobot badan pada ransum perlakuan yang menggunakan jagung. Konsumsi ransum dan konversi ransum secara rataan juga menunjukkan perlakuan menggunakan jagung menghasilkan angka konsumsi lebih tinggi dan konversi ransum lebih rendah. Penggunaan tepung limbah roti dalam ransum broiler belum mampu memberikan hasil yang sama dengan ransum yang menggunakan jagung terhadap performa broiler yang meliputi konsumsi ransum, pertambahan bobot badan dan konversi ransum.
Identifikasi Gulma Pada Kebun Singkong (Manihot Esculenta Crantz) Di Desa Nitakloang Kecamatan Nita Kabupaten Sikka Tahun 2018
Authors: Putra Sukarman Hadi Jaya , Jeclin Maryani
Published: September 2019

Penelitian tentang identifikasi gulma pada kebun singkong (Manihot esculenta Crantz) di Desa Nitakloang, Kecamatan Nita, Kabupaten Sikka bertujuan untuk mengetahui jenis-jenis gulma, kerapatan, indeks dominansi dan indeks keanekaragaman jenis. Penelitian ini telah dilaksanakan pada bulan Juli hingga Agustus 2018 dengan menggunakan metode transek garis. Jumlah stasiun yang digunakan adalah 4 stasiun yaitu dusun Baoponun, dusun Kojalaka, dusun Blatat, dusun Nitakloang. Masing-masing stasiun memiliki 3 transek garis. Setiap transek garis dibuat 10 plot pengambilan sampel. Hasil penelitian didapatkan 18 famili dan 31 spesies gulma. Nilai kerapatan gulma berkisar dari 0,008 ind/ mÂ² - 9, 116 ind/ mÂ². Nilai kerapatan gulma tertinggi yaitu 9,116 ind/ mÂ² pada spesies Ageratum conyzoides dan nilai kerapatan gulma terendah yaitu 0,008 ind/ mÂ² pada spesies Crotalaria pallida. Indeks dominansi gulma termasuk kategori dominansi rendah yaitu 0,12 dan indeks keanekaragaman jenis termasuk kategori keanekaragaman sedang yaitu H = 1,1187. Spesies gulma yang paling seringditemukan dalam setiap plot sampel adalah Ageratum conyzoides (babandotan), Euphorbia hirta (patikan), Alternanthera sessillis (rumput kremeh) dan yang paling sedikit muncul adalah Crotalaria pallida (rumput orok-orok).
Pemanfaatan Tepung Daun Pegagan (Centella asiatica) Sebagai Feed Additive Dalam Ransum Terhadap Konsumsi Ransum dan Berat Organ Fisiologis Broiler
Authors: Amir Yurni Sari , Dewi Muthia , Noor Prima Silvia , Malvin Toni , Putra Egip
Published: September 2019

Penelitian dengan memanfaatkan tepung daun pegagan sebagai feed additive dalam ransum broiler dilakukan untuk melihat pengaruhnya terhadap konsumsi ransum dan berat organ fisologis. Penelitian dilakukan di Laboratorium dan UPT Farm Politeknik Negeri Payakumbuh selama empat minggu, dengan menggunakan 100 ekor broiler yang dipelihara sejak DOC. Pakan yang diberikan berupa ransum basal dengan penambahan tepung daun pegagan. Rancangan yang digunakan adalah RAL dengan 4 perlakuan dan 5 ulangan, yaitu ransum basal 100% (A), ransum basal dengan penambahan 1,5% tepung daun pegagan (B), ransum basal dengan penambahan 3% tepung daun pegagan (C), ransum basal dengan penambahan tepung daun pegagan 4,5% (D). Variabel yang diukur adalah konsumsi ransum, persentase bobot hati dan jantung. Hasil penelitian menunjukkan bahwa pencampuran tepung daun pegagan dalam ransum sebagai feed additive tidak memberikan pengaruh yang berbeda nyata (P>0,5) terhadap konsumsi ransum, bobot hati dan jantung broiler.