bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats
Authors: Almutairi Awyed Batah , Alshammari Abdulaziz Arif A. , Rahmani Arshad Husain , Babiker Ali Yousif , Ming Long Chiau , Aldubayan Maha A. , Alhowail Ahmad H. , Mani Vasudevan
Published: October 2024

Cyclosporine A (CYP-A), a potent immunosuppressive agent, significantly impacts organ transplantation and the treatment of autoimmune disorders, and its ability to control autoimmune reactions and prevent organ rejection has made it indispensable in contemporary medicine. However, its negative effects, such as nephrotoxicity, neurotoxicity, and hepatotoxicity, limit its usefulness. The study investigated the effects of CYP-A on cognitive and neurological functions in rats over a fifteen-day period. Four groups of six rats each were treated with normal saline (control) or varying doses of CYP-A (20, 50, and 100 mg/kg). Behavioural assessments included the elevated plus maze (EPM) and novel object recognition (NOR) tests used to evaluate memory capabilities and recognition memory respectively, and the Y-maze assessed the exploration of a new environment and navigational skills. Post-experiment, brain tissues were analyzed for apoptosis, neuroinflammation, and oxidative stress markers to assess potential neurotoxicity. Histopathological analysis was also performed to provide further insights into CYP-A's effects on brain tissue. Compared to the control rats, there were significant changes in the memory parameters with two higher doses (50 and 100 mg/kg). The findings indicated that MDA, TNF-α, NF-κB, PGE2, and Caspase-3 levels increased significantly in the CYP-A 100 treatment compared to the control animals. However, a significant drop was observed in CAT, and GSH when comparing the CYP-A 100 group to the control rats. Conversely, comparable alterations were also noted in MDA, TNF-α, PGE2, Bcl-2, Bax, and Caspase-3 levels between the CYP-A 100 and other treatment groups (20 or 50 mg/kg). Moreover, the histopathological analysis revealed that as compared to the control rats, CYP-A at three different dose levels (20, 50, or 100 mg/kg, p.o.) exhibited various changes. It was noticed that as the dose levels of CYP-A increased, there was a corresponding increase in brain tissue architectural changes. Precisely, the group treated with 100 mg/kg exhibited severe haemorrhages, inflammation, necrosis, and congestion compared to the control animals. In conclusion, CYP-A induces neurotoxicity, leading to oxidative stress, neuroinflammation, apoptosis, and cognitive deficits. Understanding the underlying mechanisms of this neurotoxicity is crucial to mitigating the adverse effects of CYP-A and improving patient outcomes. Further research is needed to develop targeted therapies and enhance the safe use of CYP-A.
Uma trajetória histórica dos Poliedros da Pré-história à Antiguidade
Authors: Corrêa João Nazareno Pantoja , Pereira Ducival Carvalho
Published: October 2024

Neste artigo, considerando a relevância da história dos conteúdos matemáticos para o ensino de matemática, buscamos oferecer ao docente de matemática uma literatura que atenda à demanda relacionada ao ensino de poliedros, por meio do desenvolvimento histórico desse conceito. Apresentamos os principais estudiosos que contribuíram para o desenvolvimento dos poliedros, em ordem cronológica, destacando seus perfis biográficos e suas respectivas contribuições, desde a Pré-história até a Antiguidade Clássica. Escolhemos esse recorte temporal por ser o período em que surgiram as primeiras noções geométricas sobre formas espaciais e sólidos, como os poliedros, que mais tarde seriam formalizados e aprofundados por diversos estudiosos. Concluímos que o estudo dos poliedros se desenvolveu significativamente ao longo do tempo, e que compreender a trajetória histórica dos conteúdos matemáticos pode levar a uma compreensão mais profunda dos conceitos matemáticos para uma melhor abordagem pedagógica em sala de aula.
Proximate, Mineral, Amino Acid Composition, and Bioactive Properties of Dough Meals Supplemented with African Walnut Flour
Authors: Mayomi Peace Tumininu , Aderinola Taiwo Ayodele
Published: October 2024

This study investigated the impact of African walnut flour supplementation on the nutritional and bioactive properties of dough meals formulated with varying proportions of plantain flour. The proximate composition, mineral content, amino acid profile, color characteristics, antioxidant and anti-diabetic properties were analyzed for five different formulations: 100% plantain flour (P100), 95% plantain flour with 5% African walnut flour (PAW95), 90% plantain flour with 10% African walnut flour (PAW90), 85% plantain flour with 15% African walnut flour (PAW85), and 80% plantain flour with 20% African walnut flour (PAW80). The proximate analysis revealed significant variations, with moisture content ranging from 53.71% to 71.89%, ash content from 0.77% to 1.28%, and protein content from 3.38% to 11.14%. Notably, PAW80 showed the highest protein content. Mineral analysis showed that calcium, potassium, and magnesium levels varied significantly across the samples, with the highest calcium content observed in PAW80 (32.55 mg/kg) and the highest potassium content in PAW95 (47.80 mg/kg). Amino acid analysis indicated that essential amino acids, particularly leucine, valine, and lysine, were present in higher concentrations in the supplemented samples compared to P100. Antioxidant assays indicated that PAW80 had the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) (67.22%) and hydroxyl (73.66%) free radical scavenging activities. The in vitro anti-diabetic assays revealed that α-amylase and α-glucosidase inhibitory activities were enhanced with higher walnut flour supplementation. These findings suggest that African walnut flour can significantly enhance the nutritional quality and bioactive properties of plantain-based dough meals, and thus make it a functional food with potential health benefits.
Hematologic Predictors of Chemotherapy-Induced Neutropenia in Breast Cancer Patients Receiving Anthracycline- or Taxane-Based Chemotherapy
Authors: Muhammad Reza Fahlevi
Published: October 2024

Background: Chemotherapy-induced neutropenia (CIN) is a common and serious complication of chemotherapy in breast cancer patients, leading to increased morbidity, mortality, and treatment disruptions. This study aimed to investigate the association between hematologic profiles and the occurrence of CIN in breast cancer patients receiving anthracycline-based or taxane-based chemotherapy.
Methods: A retrospective observational analytic study with a cross-sectional design was conducted using medical records of breast cancer patients treated at the Oncology Surgery Clinic between 2022 and 2023. Sixty patients were included in the study. Hematologic profiles, including hemoglobin and leukocyte counts, were analyzed to assess their association with CIN in both anthracycline- and taxane-based chemotherapy groups.
Results: The majority of patients were aged 15-64 years (86.67%), normoweight (65%), had luminal B subtype (63.3%), and were in the locally advanced breast cancer (LABC) stage (45%). Most patients were non-anemic (Hb ≥12 mg/dL) and leukopenic (71.7% and 80%, respectively). No significant association was found between age, nutritional status, or breast cancer stage and CIN (p > 0.05). However, hemoglobin and leukocyte profiles were significantly associated with CIN in both chemotherapy groups (p < 0.05). No association was found between the type of chemotherapy (anthracycline- or taxane-based) and CIN occurrence.
Conclusion: Anemia (Hb <12 g/dL) and leukopenia are significant predictors of CIN in breast cancer patients, regardless of the chemotherapy regimen. These findings highlight the importance of monitoring hematologic profiles in these patients to identify those at higher risk of CIN and implement appropriate preventive and management strategies.
PENGARUH BRAND IMAGE DAN HARGA TERHADAP KEPUASAN KONSUMEN AQUA MELALUI KEPUTUSAN PEMBELIAN DI SUPERMARKET HARI–HARI KOTA DUMAI RIAU
Authors: Handoyo Teguh Tri
Published: October 2024

This research aims to determine the influence of brand image and price on consumer satisfaction at Hari - Hari Dumai City Riau Supermarket through intervening variables in purchasing decisions. This research uses a quantitative method with an explanatory research type. The sample in this study was taken as many as 100 people using accidental sampling technique. Hypothesis testing was carried out using a Structural Equation Model (SEM) approach based on Partial Least Square (PLS) using the SmartPLS version 3 application to test the relationship between variables. The research results show that brand image has an insignificant positive influence on Aqua purchasing decisions at the Hari - Hari Dumai City Riau Supermarket. Price and brand image have significant positive influence on Aqua purchasing decisions at the Hari - Hari Dumai City Riau Supermarket. Price does not have a significant effect on Aqua consumer satisfaction at Hari - Hari Dumai City Riau Supermarket. Purchasing decisions have a significant effect on Aqua consumer satisfaction at Hari - Hari Dumai City Riau Supermarket. Brand image has an insignificant indirect effect on Aqua consumer satisfaction through purchasing decisions at the Hari - Hari Dumai City Riau Supermarket. Price has an indirect effect on Aqua consumer satisfaction through purchasing decisions at the Hari - Hari Dumai City Riau Supermarket.
TAXONOMIC ANALYSIS OF HELMINTHS FOUND IN DOMESTIC POULTRY IN THE FERGANA VALLEY
Authors:   Researcher, Fergana State University, Uzbekistan, Abduvaliyev Baxtiyorjon Avazbekovich , Ilkhomjonovich Zokirov Islomjon ,   Professor of Department of Zoology and General Biology, DSc, Fergana State University, Uzbekistan
Published: October 2024

The modern species composition of domestic poultry helminths in the Fergana Valley was studied, and it was found to consist of 45 species. These include 12 species of cestodes, 15 species of trematodes, and 18 species of nematodes. During the research, representatives of the families Davaineidae, Ascaridiidae, Heterakidae, Strongylida, and Capillaridae (Raillietina tetragona, Skrjabinia cesticillus, Ascaridia galli, Heterakis gallinarum, Syngamus trachea) were found in almost all domestic poultry. The research on the distribution, biology, and host damage properties of these helminths is essential for developing control measures.
TECHNOLOGY FOR OBTAINING BIOCOMPONENT YARN FROM NATURAL SILK WASTE
Authors:   Tashkent Institute of Textile and Light Industry, Uzbekistan, Yusupkhodjaeva G.A. , Gulamov A.E. ,   Tashkent Institute of Textile and Light Industry, Uzbekistan, Mirzaxmedov A.S. ,   Tashkent Institute of Textile and Light Industry, Uzbekistan
Published: October 2024

The paper presents the results of a study on the development of technological parameters for the preparation of blended yarn from cotton fibers and secondary waste of natural silk. A new technological chain for the production of mixed yarns in modern cotton spinning equipment is given, taking into account their technological capabilities, as well as physical, mechanical and technological indicators of the resulting new mixed yarn. Also, the indicators of filling the loom, which received the fabric, are given. In conclusion, the physical and mechanical indicators and the results obtained in the certification laboratory of the institute are given.
THE ISSUE OF INVESTIGATING THE VOCABULARY OF WOMEN'S CLOTHING AND FASHION IN LINGUISTICS
Authors:   Lecturer At Fergana State University, Uzbekistan, Gulruh Tillaboyeva
Published: October 2024

This article explores the linguistic aspects of the vocabulary associated with women's clothing and fashion. It highlights the significance of studying how language reflects cultural, social, and gender norms through fashion-related terms. The dynamic and context-dependent nature of this vocabulary is discussed, along with its connection to historical changes, globalization, and media representations. The research emphasizes the interdisciplinary nature of this topic, intersecting with sociology, gender studies, and cultural anthropology, to uncover the socio-cultural ideologies embedded in fashion discourse. This study aims to contribute to a deeper understanding of how language shapes perceptions of identity, aesthetics, and social roles within the domain of women’s fashion.
TYPES AND FEATURES OF PRONOUNS IN THE KOREAN LANGUAGE
Authors:   ISFT Institute, Department of Social Sciences and Humanities, Assistant, Uzbekistan, Zoyirovna Yarbekova Umida
Published: October 2024

This article aims to highlight the pronouns of the Korean language and their distinctive features. In Korean, pronouns are used to indicate clarity and to indicate a person. The uniqueness of this language is that the use of pronouns varies depending on the social status and the level of respect in the sentence. The article also provides information about the grammatical functions of Korean pronouns, their place in a sentence and changes in content. This article serves as a useful resource for Korean language learners on how to use pronouns correctly and effectively.
CULTURAL GLOBALIZATION OF TOURISM AND ITS IMPACT ON THE BEHAVIOR OF THE LOCAL COMMUNITY IN KARBALA GOVERNORATE
Authors:   Al-Furat Al-Awsat Technical University, Technical Institute / Najaf, Iraq, Al Masoudi Dr. Layla Jawad Hussein
Published: October 2024

The research aims to identify the extent of the impact of cultural globalization of tourism on the behavior of the local community in Karbala Governorate. It underscores the importance of knowledge exchange as a key strategy in addressing the challenges posed by cultural globalization. The study assumed a positive and significant impact relationship of cultural globalization of tourism on the behavior of the local community. To achieve its objectives, a questionnaire was designed that included (17) paragraphs to collect data from the research sample of (75) individuals. The descriptive analytical approach was adopted when the data was collected. Hypotheses were tested using a set of statistical methods with the help of the statistical program (SPSS. V.23). After conducting the statistical analysis; the research concluded that there is a significant statistical correlation between the cognitive dimension and the behavior of the local community, and accordingly, there is an impact. The most important recommendation was to work on exchanging ideas, opinions, information, and experiences to increase knowledge of the importance of tourism and its development. This call for knowledge exchange invites the audience to be part of the solution, fostering a sense of engagement and shared responsibility.
ABNORMAL UTERINE BLEEDING AT DIFFERENT PERIODS OF A WOMAN'S LIFE
Authors:   Assistant Samarkand State Medical University, Samarkand, Uzbekistan, Samadovna Karimova Gulchekhra
Published: October 2024

Abnormal uterine bleeding (AUB) is a common gynecological problem affecting women at different stages of life: from adolescence to menopause. This article discusses statistical data and the main causes leading to AUB in different age groups. Attention is drawn to the characteristic features of menstrual disorders in adolescents, women of reproductive age and during menopause, and modern treatment, including both conservative and surgical methods, is presented. Research shows that adequate diagnostics and an individualized approach to treatment can significantly improve the quality of life of patients and prevent serious complications. The article emphasizes the importance of early medical care and regular gynecological examinations to ensure women's health at all stages of their lives.
CREATIVE ENTREPRENEURSHIP AND THE ECONOMIC CONTENT OF ADOLESCENT GIRLS' ENTREPRENEURIAL ACTIVITY
Authors:   Doctoral Candidate At The ", Nigora Tulaganova ,   Family And Gender",   Scientific Research Institute Under The Committee On Family And Women Of The Republic Of Uzbekistan
Published: October 2024

The article discusses how business ideas should be structured for adolescent girls and how, as companies grow, founders must diversify their products and services, diversify their projects, and search for directions to develop their projects.
USING ICT IN GEOGRAPHY LESSONS
Authors:   PhD, Senior Lecturer At NUUZ, Uzbekistan, Rustamjanovna Xosilova Farida
Published: October 2024

The article raises the topic of using information technology in geography lessons, which significantly improves the quality of teaching subjects and the interest of students in it. The article also discusses the advantages and types of ICT, methods and techniques, the importance of using information technology at different stages of the lesson.
АNАLYSIS ОF FОRЕIGN ЕXРЕRIЕNСЕS ОN IMРRОVING РUРILS' NАTURАL SСIЕNTIFIС LITЕRАСY BАSЕD ОN А HISTОRIСАL АРРRОАСH
Authors:   Rеsеаrсhеr оf Nаmаngаn Stаtе Рedagogy Institutе, Uzbekistan, ugli Uzоkbоеv Khоjiаkbаr Kаbiljаn
Published: October 2024

Thе study оf nаturаl sсiеnсеs рlаys а сruсiаl rоlе in shарing studеnts' intеllесtuаl аnd рrасtiсаl skills, fоstеring а bеttеr undеrstаnding оf thе wоrld. Imрrоving nаturаl sсiеntifiс litеrасy is а рriоrity in еduсаtiоnаl rеfоrms wоrldwidе, with а signifiсаnt fосus оn histоriсаl аррrоасhеs thаt trасе thе dеvеlорmеnt оf sсiеntifiс thоught. This аrtiсlе аnаlyzеs fоrеign еxреriеnсеs in еnhаnсing рuрils' nаturаl sсiеntifiс litеrасy thrоugh histоriсаl mеthоds, highlighting bеst рrасtiсеs frоm соuntriеs thаt hаvе suссеssfully intеgrаtеd histоriсаl саsе studiеs intо sсiеnсе сurriсulа. Соuntriеs suсh аs Finlаnd, Jараn, аnd thе Unitеd Stаtеs hаvе рiоnееrеd еffоrts tо intеrlink sсiеntifiс соnсерts with thеir histоriсаl dеvеlорmеnts, thеrеby dеереning studеnts' соmрrеhеnsiоn аnd соntеxtuаl undеrstаnding. By еxаmining thеsе аррrоасhеs, еduсаtоrs in vаriоus соntеxts, inсluding Uzbеkistаn, саn lеаrn hоw tо fоstеr а strоngеr соnnесtiоn bеtwееn sсiеntifiс litеrасy аnd histоriсаl undеrstаnding in studеnts. Thе аrtiсlе соnсludеs by оffеring rесоmmеndаtiоns fоr аdарting thеsе intеrnаtiоnаl рrасtiсеs tо diffеrеnt еduсаtiоnаl systеms, соnsidеring lосаl histоriсаl соntеxts аnd еduсаtiоnаl gоаls.
METHODOLOGY FOR IDENTIFYING STUDENTS' RESEARCH SKILLS THROUGH THE ORGANIZATION AND CONDUCT OF CLUB ACTIVITIES RELATED TO THE "MECHANICS" SECTION OF PHYSICS
Authors:   Lecturer At The ", Abdukarimovich Raxmonov Ikrom ,   General Physics",   Department At Termez State University, Uzbekistan
Published: October 2024

This article explores the methodology for identifying and developing students' research skills through the organization and conduct of club activities focused on the "Mechanics" section of physics. The study emphasizes the importance of integrating theoretical knowledge with practical activities to foster students' investigative abilities. The principle of gradual progression from simple to complex tasks is applied to ensure consistent skill development. Additionally, the article highlights the role of hands-on problem-solving, laboratory experiments, and the use of physics equipment in enhancing the educational process. The research demonstrates that students’ participation in structured extracurricular activities promotes not only academic growth but also contributes to their ability to apply scientific knowledge to real-world problems.
WORDS BORROWED FROM FOREIGN LANGUAGES AND THEIR INFLUENCE ON THE FORMATION AND DEVELOPMENT OF THE WORD STOCK OF THE ENGLISH LITERARY LANGUAGE
Authors:   Doctor Of Philosophy In Philology (Phd), Associate Professor, Uzbekistan State University Of World Languages, Uzbekistan, Khamzaev Sobir Amirovich
Published: October 2024

The present article is dedicated to the factors of enrichment of the English literary language through different periods of its development. As one of the most productive ways of enriching the word stock of the English language the author regards borrowings from other languages. There is made an attempt to classify languages, from which English derived words into several categories. One way to do this is done through the historicalfactor. Some linguistic and extra linguistic factors of enriching the word stock of English are also analyzed in the article. As the languages, which had greatly influenced the word stock of English the author regards Latin, French and Scandinavian languages.
IMPORTANCE OF INTERNATIONAL PRINCIPLES OF COOPERATIVE ACTIVITY IN CLUSTER ACTIVITIES
Authors:   Head Of The Department Of The Higher School Of Judges Under The Supreme Council Of Judges Of The Republic Of Uzbekistan, Associate Professor, Candidate Of Legal Sciences, Uzbekistan, Boratovich Kholbaev Sobir
Published: October 2024

This article provides scientific opinions and discussions about the types of international cooperative principles developed by the International cooperative union, their content, role in the economy, as well as their significance in conducting economic policy related to the formation and development of the newly introduced cluster model in Uzbekistan. Some of the issues in cluster activity and their legal solutions are also discussed.
Enhanced salience of edge frequencies in auditory pattern recognition
Authors: Bürgel Michel , Mares Diana , Siedenburg Kai
Published: October 2024

Within musical scenes or textures, sounds from certain instruments capture attention more prominently than others, hinting at biases in the perception of multisource mixtures. Besides musical factors, these effects might be related to frequency biases in auditory perception. Using an auditory pattern-recognition task, we studied the existence of such frequency biases. Mixtures of pure tone melodies were presented in six frequency bands. Listeners were instructed to assess whether the target melody was part of the mixture or not, with the target melody presented either before or after the mixture. In Experiment 1, the mixture always contained melodies in five out of the six bands. In Experiment 2, the mixture contained three bands that stemmed from the lower or the higher part of the range. As expected, Experiments 1 and 2 both highlighted strong effects of presentation order, with higher accuracies for the target presented before the mixture. Notably, Experiment 1 showed that edge frequencies yielded superior accuracies compared with center frequencies. Experiment 2 corroborated this finding by yielding enhanced accuracies for edge frequencies irrespective of the absolute frequency region. Our results highlight the salience of sound elements located at spectral edges within complex musical scenes. Overall, this implies that neither the high voice superiority effect nor the insensitivity to bass instruments observed by previous research can be explained by absolute frequency biases in auditory perception.
Crossmodal correspondence of elevation/pitch and size/pitch is driven by real-world features
Authors: McEwan John , Kritikos Ada , Zeljko Mick
Published: October 2024

Crossmodal correspondences are consistent associations between sensory features from different modalities, with some theories suggesting they may either reflect environmental correlations or stem from innate neural structures. This study investigates this question by examining whether retinotopic or representational features of stimuli induce crossmodal congruency effects. Participants completed an auditory pitch discrimination task paired with visual stimuli varying in their sensory (retinotopic) or representational (scene integrated) nature, for both the elevation/pitch and size/pitch correspondences. Results show that only representational visual stimuli produced crossmodal congruency effects on pitch discrimination. These results support an environmental statistics hypothesis, suggesting crossmodal correspondences rely on real-world features rather than on sensory representations.
A synopsis of Friesodielsia (Annonaceae) in New Guinea
Authors: Ezedin Z
Published: October 2024

The lianescent genus Friesodielsia has been poorly documented and studied in the New Guinea region, with only a single species, F. subaequalis, known thus far. Three species are newly described for the island and all four are illustrated here. Friesodielsia papuana
resembles other glaucous-leaved species from western Malesia, namely F. glauca, but can be distinguished through a combination of laminar and floraltraits. Friesodielsia ferralta is described from a single montane specimenat 1400m, representing the highest known collection for
the genus; it differs from the lowland F. papuana in its rusty indument, longer flowering pedicels, and smaller sepals. Frieso dielsia yelaensis is described from a single specimen from Rossel Island, representing both the southernmost and eastern mostextent for the genus. It
has adistinct morphology with its strongly acuminate to caudate leaf apex, subsessile flowers, large foliaceous medial bracts and sepals. A key to the species in New Guineais provided.
Leveraging ML for Anomaly Detection in Healthcare Data Warehouses
Authors: Devi Arun Kumar Ramachandran Sumangala
Published: October 2024

The rapid emergence of digitalisation leads to unprecedented growth in the generation of the healthcare sector-particularly EHRs and medical equipment data. This extended the way for challenges for integrity in managing data and anomaly detection, including fraudulent transactions, medication errors, and many more system failures. Modern healthcare data poses a challenge to traditional methods of anomaly detection due to high and complex dimensionality. Machine learning provides a strong solution, using algorithms such as Gaussian Mixture Models, One-Class SVM and deep learning algorithms such as Autoencoders, and Recurrent Neural Networks in the detection of anomalies in healthcare data warehouse settings [1]. This study reports how ML can help advance care for patients, enable the validity of the data and reduce costs through real-time monitoring, fraud detection, and early detection of diseases. Applying anomaly detection through ML would most likely bring better operational performance, patient safety, and decision-making in health care for organizations as issues of poor data quality, lack of interpretability of models, and real-time detection would be addressed [2].
Incidencia de la ejecución del Plan de Mantenimiento en la Satisfacción del Cliente Externo del Hotel Hilton Colon Guayaquil
Authors: Murillo Encarnacion Wilvir Gary
Published: October 2024

La investigación ha demostrado que la correcta ejecución del plan de mantenimiento en el hotel Hilton Colon Guayaquil (HHCG) incrementa la sensación de satisfacción de los clientes externos lo que causa fidelidad a la marca por la calidez de la hospitalidad que profesa como misión de la empresa esto desembocara en una mayor utilidad, además de prolongar la vida útil de la propiedad. Por ello este trabajo pretende describir las fortalezas y debilidades de la ejecución del plan de mantenimiento y la implementación de procesos de innovación y mejora. La metodología utilizada tiene finalidad aplicada, su alcance es descriptivo-estadístico, nivel de enfoque, estudio cuantitativo de tipo analítico y alcance racional, los cuales permiten sustentar los resultados. En el presente trabajo se encontró que la colaboración de los stakeholders tanto como de los shareholders resulta estratégica ya que el proceso de ejecución de un plan de mantenimiento en el HHCG depende de todos los departamentos administrativos y operativos principalmente del departamento de Ingenieria.
Eficacia de Ley 30364 y Aplicación de Medidas Económicas para las Víctimas de Violencia contra la Mujer, Los Olivos, 2022
Authors: Caballero Montero Beatriz Hortencia , Minaya Cuba Manuel
Published: October 2024

Objetivo fue determinar la correlación entre la aplicación de la Ley 30364 y la eficacia de las medidas económicas para proteger a las víctimas de violencia contra la mujer y los integrantes del grupo familiar. método de tipo aplicada, enfoque cuantitativo, hipotético-deductivo, nivel correlacional y diseño no experimental; población de 135 personas y muestra de 100p; se aplicó la técnica de la encuesta y el instrumento fue el cuestionario distribuido según las dimensiones de las variables. Los resultados confirmaron la hipótesis de investigación demostrándose que la aplicación de la Ley 30364 se relaciona significativamente con la eficacia de las medidas económicas para la protección de las víctimas de la violencia contra la mujer y los integrantes del grupo familiar. conclusión existe una correlación positiva alta entre las variables puesto que el coeficiente de correlación fue de 0.774; además, el análisis descriptivo muestra que solamente el 32% de los encuestados señalaron que la Ley 30364 es buena. Concluyendo que las medidas económicas se tienen que incorporar en las resoluciones para proteger a las víctimas de violencia contra la mujer y grupos vulnerables.
La Música y su Incidencia en la Recordación: Análisis de Canciones Propuestas por un Grupo de 87 Personas
Authors: Vallejo Bastidas James Guillermo
Published: October 2024

La presente investigación se plantea a partir de los postulados de la neuroeducación, intentando encontrar elementos que puedan permitir potenciar los procesos de aprendizaje en la escuela. En este sentido, la memoria es fundamental en el aprendizaje humano, y algunos investigadores neurocientíficos han demostrado que el elemento emocional tendría un papel fundamental tanto en la construcción de memorias, como en la recordación. Es por lo anterior, y partiendo de la capacidad que se le atribuye a la música para generar diferentes estados de emoción y activación, que se intenta establecer si existen elementos específicos de esta, que se puedan utilizar de manera intencionada para desarrollar y potenciar la recordación en espacios y procesos de enseñanza y aprendizaje. Este estudio tuvo como objetivo general establecer cuáles son algunos de los elementos musicales más recurrentes asociadas con la recordación en una muestra de 87 canciones.  Para la recolección de datos se recurrió a una encuesta en línea donde se solicitó a los participantes escoger una canción que evocara algún recuerdo personal. Posteriormente se analizaron elementos puntuales de la música propuesta como Tonalidad, Tempo, Afinación y Género, para así poder identificar las más frecuentes y las posibles asociaciones entre estos. Los resultados muestran que la tonalidad más frecuente es Sol mayor (G), el rango de tempo más usual va desde 76 BPM a 168 BPM que indican velocidades moderadas. En el caso del Género más frecuente fue el Pop y la afinación más usada es 440 Hz.
Estigmatización Social de las Estudiantes de la Facultad de Enfermería que Cursaron con Embarazo Adolescente
Authors: Carbajal Mondragón María Magdalena , Picazo Carranza Alma Rosa , González Villegas Graciela , Alcántar Zavala Lilia Alicia , Negrete Ruiz Josefina , Portillo Esquivel Andrea
Published: October 2024

Introducción. El embarazo adolescente es un problema de salud que pone en riesgo tanto la vida de la madre como del hijo ya que durante esta etapa las mujeres pueden presentar múltiples complicaciones como endometritis puerperal y eclampsia. Según la organización mundial de la salud es considera el embarazo adolescente a la mujer de los 10 años hasta los 19 años. Objetivo. Identificar el estigma social de las estudiantes de la facultad de enfermería que cursaron con embarazo adolescente. Metodología. Estudio cuantitativo, diseño no experimental, descriptivo y transversal, se utilizó el instrumento que evaluó la estigmatización de las adolescentes construido por la escala tipo Likert, donde la muestra fue 44 estudiantes de la Facultad de Enfermería que cumplieron los criterios de evaluación. Resultados. se observa que el 40% de las encuestadas fueron de un rango de edad de 19 años, el 32.5% vive en unión libre, el 35% de las encuestadas fue de séptimo semestre; en cuanto al nivel de estigmatización el 72% de las estudiantes presentaron algún tipo de estigmatización social durante el embarazo. Conclusiones. Es importante que el personal de salud realice intervenciones educativas para disminuir el embarazo adolescente y así mismo la implementación periódica para el seguimiento de las adolescentes que presentan embarazo adolescente.
Abordaje por Vía Transepto-Esfenoidal en Trauma de Hipófisis. Evolución de Tratamiento Neuroquirúrgico y la Microcirugía, Presente y Futuro
Authors: Pilalumbo Choloquinga M. Edwin Rubén , Rea Moscoso José Luis , Lema Balla José Roberto , Venegas Ortiz Yolanda Maribel , Lema Balla Juan Carlos
Published: October 2024

Los traumas hipofisarios son localizados a nivel de la silla turca, que suponen entre el 7% y el 17% de todos los tumores intracraneales. En cuanto a los adenomas asintomáticos, la prevalencia en autopsias y estudios de resonancia magnética es de alrededor del 16,7% al 20%, y muy pocos se vuelven sintomáticos. Por lo tanto, este tipo de abordaje ha sufrido importantes mejoras a lo largo de los años, convirtiéndose hoy en día en uno de los abordajes más utilizados y preferidos por los otorrinolaringólogos para el tratamiento de heridas a nivel de la silla turca, porque se considera un método seguro, inofensivo y técnicoforma un método fácil de realizar. El objetivo de esta publicación es describir las características de cada una de las variantes del abordaje transeptosfenoidal en el trauma hipofisario, revisar su evolución histórica, discutir las técnicas actuales y descubrir desarrollos futuros, se  ha aplicado una investigación con un enfoque descriptivo, para brindar un panorama detallado y rico de las experiencias y percepciones de otros investigadores que han realizado trabajos relacionados con el tema de la cirugía transesfenoidal, se utilizó una revisión de la literatura de diferentes bases de datos.
Pedagogías de la Muerte y la Conciencia en los Contextos Escolares Ecuatorianos
Authors: Fernanda Córdoba Évelyn , Lovato Alvarado Verónica Cecilia , Intriago Rengifo José Carlos , Párraga Parrales Katterine Daniela , Lutuala Faz Vilma Verónica , García-Umaña Andrés
Published: October 2024

El sistema educativo ecuatoriano establece objetivos y principios de acuerdo al marco legal y conceptual de una Educación de Calidad y por ende una búsqueda de desarrollo nacional que beneficie a los niños, niñas, jóvenes y adultos, asimismo dar solución a distintas problemáticas educativas, evitar la exclusión y alcanzar diferentes oportunidades; escenarios que pueden ser tratados en los centros escolares mediante la aplicación de diversas pedagogías. En el presente manuscrito se propone el análisis de la pedagogía de la muerte y de la conciencia como un punto clave para generar conocimiento, procedimientos y actitudes, contribuyendo a la interdisciplinariedad de la educación, acorde a las manifestaciones de los hechos educativos, a nivel analítico, comprensivo y filosófico, en el cual se tratará poder encontrar un sentido a la educación, percibido desde ciertos principios, bases, fundamentos y artículos de la constitución ecuatoriana (CRE), el Plan Nacional del Buen Vivir (PNBV), la Ley Orgánica de Educación Intercultural (LOEI) y una revisión literaria.
Craniectomía Descomprensiva para la Hipertensión Intracraneal Traumática: como una Estrategia Neuroquirúrgica Práctica. Desafios frente a Modalidades de Tratamiento Convencionales
Authors: Pilalumbo  Choloquinga Edwin Rubén , Guevara Álvarez M. Ariana Karolina , Lema Balla C. José Roberto , Venegas Ortiz M. Yolanda Maribel , Lema Balla C. Juan Carlos
Published: October 2024

Debido al cierre de las suturas y fontanelas en la infancia, el cráneo es una estructura no alargada y con un volumen constante independientemente de sus componentes. La hipertensión intracraneal se define como un aumento sostenido de la PIC por encima de 20 mmHg durante más de 10 minutos. La detección y el manejo temprano de la hipertensión intracraneal es necesario para aplicar las medidas terapéuticas necesarias para prevenir estas lesiones isquémicas. Es importante abordar a estos pacientes con un manejo completo y oportuno, siguiendo todas las recomendaciones basadas en la evidencia que se discutirán en esta revisión de la literatura; para evitar herniación de las estructuras cerebrales y daño neurológico irreversible al paciente. La craniectomía descompresiva es un procedimiento quirúrgico que consiste en la resección del hueso craneal es una abertura en la duramadre para ayudar a descomprimir el espacio intracraneal después de un traumatismo craneoencefálico. En pacientes con edema cerebral severo, este procedimiento reduce el riesgo de un mayor aumento de la presión intracraneal, promueve la descompresión venosa generalizada y previene la hernia cerebral. El objetivo de esta investigación es analizar la craniectomía descompresiva (CD) como una estrategia neuroquirúrgica práctica y compararla con modalidades de tratamiento convencionales.
Acercamiento Diagnóstico para la Virtualización de un Programa de Posgrado en la Universidad Autónoma Chapingo
Authors: Álvarez González Evelina , Barrios Puente Gerónimo , García Sánchez Roberto Carlos , Pérez Soto José Francisco
Published: October 2024

En un periodo como el momento actual, en donde el conocimiento se vuelve pilar fundamental de la sociedad, la educación adquiere un papel relevante, que implica otorgarle mayor importancia, este planteamiento asociado a las TIC (Tecnologías de la Información y la Comunicación) nos remite a la propuesta de implementación de programas en Educación a Distancia Virtual (EaDV). El Doctorado en Ciencias en Educación Agrícola Superior (DCEAS), de la Universidad Autónoma Chapingo (UACh), actualmente, proporciona educación a nivel posgrado de carácter presencial. El objetivo principal de esta investigación fue realizar un estudio diagnóstico en el programa DCEAS de la UACh para generar conclusiones y recomendaciones necesarias en la búsqueda de una propuesta para la transición del programa de educación presencial a EaDV (Educación a Distancia Virtual). La metodología empleada fue cualitativa interpretativa, bajo el paradigma de la teoría fundamentada Strauss y Corbin (2002). El enfoque metodológico correspondió a un estudio diagnóstico, en el que se retomó la propuesta generada por Castillo et al. (2007). Los resultados y conclusiones muestran que el departamento DCEAS ofrece posibilidades para un buen desarrollo de la EaDV.
CONTROL INTERNO Y SU IMPACTO EN LA SATISFACCIÓN DEL CLIENTE EN LA CAJA MUNICIPAL DE AHORRO Y CRÉDITO DE CUSCO: UN ESTUDIO EN LA REGIÓN PUNO
Authors: Lorenzo Samo Martin , Villalta Zea Alí , Condori Manzano Hugo Freddy , Quispe Gómez Fredy , Quispe Condori Jose Banyino , Perez Lima Ynes , Mamani Quispe Elena Zenaida
Published: October 2024

Objetivo: Determinar la influencia del control interno en la satisfacción de los clientes de la Caja Municipal de Ahorro y Crédito - Cusco, en la región Puno, durante los periodos 2020-2023. Métodos: La investigación se enmarco dentro del enfoque cuantitativo, diseño no experimental de corte transversal. Se utilizaron encuestas para recopilar datos sobre las percepciones de los trabajadores respecto al ambiente de control interno, la evaluación de riesgos, las actividades de control y el nivel de información y comunicación. Resultados: Mostraron que un 48% de los trabajadores están totalmente de acuerdo con la efectividad del control interno, destacando la responsabilidad administrativa y la gestión oportuna de la gerencia. En cuanto a la evaluación de riesgos, el 48.4% de los empleados coincidieron en la implementación efectiva de medidas como la planificación de contingencias y la tecnología disponible. Las actividades de control, respaldadas por un 50.4% de los trabajadores, demostraron ser efectivas, con una notable vigencia de licencias y cumplimiento de leyes. Sin embargo, el nivel de información y comunicación recibió un apoyo parcial del 43.2%, indicando áreas de mejora. Conclusão: La implementación de un control interno efectivo en la Caja Municipal de Ahorro y Crédito - Cusco tiene un impacto positivo en la satisfacción del cliente, al promover una administración responsable y orientada a los objetivos institucionales.
PORTUGAL: ESTUDO DE UMA INSTITUIÇÃO ACADÉMICA CONTÁBIL PORTUGUESA
Authors: Gonçalves Miguel
Published: October 2024

Enquadrado no estudo da história das instituições de ensino de Contabilidade em Portugal, o artigo tem por objectivo referenciar o quarto de século (1844-1869) da sucessora da Aula de Comércio – a Escola de Comércio de Lisboa. Integrada no Liceu Nacional de Lisboa, após a extinção da Aula de Comércio, em 1844, a Escola de Comércio assistiu à perda de prestígio social da Contabilidade, também para isso contribuindo a ausência de garantias dadas aos diplomados de Comércio.
PROGRAMAÇÃO FETAL EM RUMINANTES
Authors: Damiani Camila de Farias , Fluck Ana Carolina , Rizzo Fábio Antunes , de Sá Haylleen Aparecida Oliveira Menezes , da Silveira Elivelton de Salles
Published: October 2024

O objetivo dessa revisão é esclarecer o conceito de programação fetal, termo utilizado para o potencial de desenvolvimento da prole em meio intrauterino. Durante o período inicial da gestação ocorre a formação de fibras musculares, através dos processos de miogênese primária e secundária, além da formação do tecido adiposo a partir do segundo terço da gestação. Estudos realizados demonstram que os processos de miogênese e adipogênese estão diretamente ligados com a nutrição da mãe nos dois primeiros terços da gestação, porém, o cuidado direto com essa nutrição geralmente ocorre no terço final, visando o crescimento do feto e a recuperação do escore de condição corporal da mãe. O manejo e nutrição balanceada são responsáveis pelo potencial destas etapas e como resultado um animal com potencial produtivo e reprodutivo no futuro.
TEOLOGIA DA PROSPERIDADE – FUNDAMENTOS, HISTÓRICO E CRÍTICAS: UM GUIA VISUAL E MULTIDISCIPLINAR
Authors: VIANA JUNIOR Carlos José , VIANA Bruna Carla Leite
Published: October 2024

Neste capítulo, apresentamos uma visão geral dos conteúdos propostos ao longo do livro, abordando a Teologia da Prosperidade, um Movimento Religioso que inclui temas como riqueza, saúde, bem-estar, sucesso, poder e felicidade dentro do Movimento de Fé. Este movimento ganhou notoriedade significativa e tornou-se um movimento evangélico, com muitos pregadores desenvolvendo conceitos e técnicas como meios de alcançar a prosperidade e satisfação (gozo). No entanto, há também um grande grupo de teólogos que questionam a base bíblica dessa teologia e a veem como um perigo para os princípios fundamentais do cristianismo. Objetivo: fornecer um conceito geral da Teologia da Prosperidade e sua propagação pelos principais expoentes desse movimento, desde sua origem nos Estados Unidos até seu estado atual no protestantismo brasileiro. Não visamos tomar um lado – o que deixamos a encargo de você, leitor – mas sim, apresentar os pontos e contrapontos para fornecer uma base para mais pesquisas, debates, posicionamentos e desenvolvimento de melhores abordagens teórico-bíblicas. Metodologia: como ferramenta pedagógica, usamos várias ferramentas, como Mapas Mentais, Mapas Conceituais, Tabelas Comparativas e Infográficos, para facilitar o aprendizado e a compreensão. Pretendemos auxiliar no esclarecimento deste tema, tanto para leigos quanto acadêmicos, seminaristas ou universitários. Para isso, utilizamos recursos visuais ao longo do livro, com a finalidade de proporcionar um melhor nível de aprendizagem. Sonhamos com este material sendo utilizado por professores e alunos, pais e mães, jovens e anciãos. Percebemos, por meio da literatura disponível sobre os processos do conhecimento e da ciência, chamado epistemologia, que atualmente, dentro do campo teológico, poucos recursos trabalham conjuntamente o lado racional com o emocional da aprendizagem, embora seja evidente que a conurbação desses recursos afete diretamente e positivamente os aspectos comportamentais e cognitivos dos leitores. Conclusão: nota-se que Teologia da Prosperidade é um movimento religioso que vincula riqueza, saúde e sucesso à fé cristã, desde suas origens nos Estados Unidos até sua influência no protestantismo brasileiro. Apresentamos a definição e metodologia pedagógica, incluindo recursos visuais como mapas mentais e infográficos. Analisamos o conceito bíblico de prosperidade e discutimos a historicidade da Teologia da Prosperidade e seus principais pensadores, como Essek William Kenyon e Kenneth Erwin Hagin, além de abordar a Confissão Positiva e as críticas recebidas. Também exploramos as bases filosóficas e teológicas do movimento, preparando o leitor para uma análise mais profunda nos capítulos seguintes do livro do autor, que ainda está em fase de escrita e de revisão.
A PROMESSA DA PROSPERIDADE EM UMA ANÁLISE CRÍTICA DO DISCURSO LITERÁRIO E CULTURAL DO MOVIMENTO DA FÉ: UM GUIA VISUAL E MULTIDISCIPLINAR
Authors: VIANA JUNIOR Carlos José , VIANA Bruna Carla Leite
Published: October 2024

Neste capítulo, apresentamos reflexões acerca da Teologia da Prosperidade como um movimento religioso que conecta a fé cristã à obtenção de riqueza e saúde. Originado no século XX, o movimento encontrou em figuras como Essek William Kenyon e Kenneth Hagin seus principais expoentes. Ao longo das décadas, essa doutrina se infiltrou em várias vertentes do cristianismo, especialmente no neopentecostalismo, encontrando terreno fértil no Brasil. A partir de uma leitura particular das Escrituras, a Teologia da Prosperidade promete bênçãos materiais e físicas aos seus adeptos como resultado de uma fé ativa e confissões positivas. Objetivo: O objetivo deste estudo é analisar as origens históricas e filosóficas da Teologia da Prosperidade, bem como sua evolução e impacto no contexto do neopentecostalismo brasileiro. Busca-se explorar os pilares fundamentais dessa doutrina, incluindo a Confissão Positiva, a dinâmica entre fiel e líder religioso, e a premissa de que doações financeiras são necessárias para se alcançar prosperidade. A análise visa contribuir para o debate acadêmico, oferecendo uma compreensão aprofundada e crítica sobre como esse movimento tem influenciado práticas e doutrinas religiosas no Brasil. Metodologia: A pesquisa adotou uma abordagem multidisciplinar, combinando análises teológicas, sociológicas e históricas. Foram examinados textos fundamentais da Teologia da Prosperidade, discursos de seus principais líderes e práticas observadas em igrejas neopentecostais brasileiras. A análise teológica focou na interpretação das Escrituras proposta pelo movimento, enquanto a perspectiva sociológica investigou o impacto nas comunidades de fé e a relação entre líderes e seguidores. A abordagem histórica permitiu traçar a evolução do movimento e sua adaptação ao contexto brasileiro. Conclusão: Os resultados da análise revelam que a Teologia da Prosperidade, embora vista por seus defensores como uma expressão legítima da fé cristã que empodera os crentes a reivindicar promessas divinas, é criticada por distorcer as Escrituras e promover uma visão materialista da fé. O movimento tem exercido uma influência significativa no protestantismo brasileiro, moldando práticas e doutrinas de várias denominações. Contudo, levanta sérias questões éticas e teológicas, especialmente no que diz respeito à manipulação da fé para obtenção de ganhos financeiros. Este estudo contribui para a literatura acadêmica ao oferecer novas perspectivas sobre a Teologia da Prosperidade e seu florescimento em diferentes contextos culturais. Em termos práticos, os insights fornecidos podem auxiliar líderes religiosos, educadores e teólogos a enfrentarem as complexidades desse movimento, promovendo uma fé mais equilibrada e fundamentada biblicamente.