bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGELOLAAN KEUANGAN KOPERASI MENDUKUNG KEMANDIRIAN EKONOMI RAKYAT PADA PRA KOPERASI MAJU MAKMUR UNGARAN
Authors: Ratnawati Juli , Sumaryati Anna , Mardjono Enny Susilowati
Published: October 2023

In an organization, an important component in creating accountability from the organization is the financial report. The financial information presented by the organization serves as a foundation for consideration in making decisions and is an element in carrying out organizational accountability effectively. Cooperatives are the pillars of the Indonesian economy. The government strongly encourages the growth and development of cooperatives because cooperatives have a noble aim for the welfare of their members. This community service aims to assist and provide training in preparing cooperative financial reports to partners, namely Pra Koperasi Maju Makmur Semarang Regency so that they can independently manage financial documents and present their financial reports for the internal and external interests of the cooperative. The implementation method is by providing understanding to the management and members of cooperatives regarding the types of financial reports, knowledge of cooperative laws and how to prepare cooperative financial reports in a structured manner. The results of the community service show that the training participants understand the preparation of comprehensive cooperative financial reports.
PENINGKATAN STRATEGI PEMASARAN DAN BRANDING UMKM DESA PENTUR KABUPATEN BOYOLALI MELALUI DIGITAL MARKETING
Authors: Kusumaningrum Andriani , Harjanto Sri , Siswanti Sri , Setiyowati Setiyowati , Purwati Mita , Vulandari Retno Tri
Published: October 2023

Economically, most of the residents of Pentur Village are farmers, both working in paddy fields and fields, apart from that, it is also a center for the bamboo woven craft industry which is the livelihood of some of the residents. In fact, Pentur village also has a fairly well-known foundation called "Tumpi Redhouse" which was founded on July 16 2012. In this library there are 2500 book collections, hundreds of film collections, various magazines and reference books. Apart from being a place to read, this library also holds various community empowerment activities such as agricultural activities and MSME groups. Several arts live in this village, various traditional ceremonies such as cleaning the village with shadow puppet performances are still held every year, apart from that, reog art, music and painting are also the breath of artistic activities in this village. The aim of this service is to implement visuals in content and digital marketing formats to improve the economy of Pentur village. Methods for implementing the service include content creator and digital marketing workshops for MSMEs in Pentur village. The resulting output is the implementation of the workshop. At the end of this program, activities will be published via print and online media.
Exploring Gender and Leadership Trajectories in Academic Anesthesiology: Qualitative Content Analysis of Turkish Department Chairs
Authors: Adiguzel Senay Canikli , Akyurt Dilan
Published: October 2023

Background and aim: In the evolving landscape of anesthesiology, anesthesiologists play a pivotal role that extends beyond providing clinical care. Anesthesiologists exhibit adept collaboration skills, particularly in high-stress environments, showcasing their leadership and management proficiencies. While the terms "leader" and "manager" hold distinct connotations, leaders often fulfill managerial roles. Gender disparities are prevalent in anesthesiology leadership, mirroring broader trends across professions. In 2023, this study conducts a bibliometric analysis of academic professionals holding department head positions in Turkish anesthesiology and reanimation, scrutinizing gender distribution and categorizing them based on their institutions' administrative attributes to illuminate leadership patterns within the field.
Material & Methods: The hospitals in our country that offer anesthesiology and reanimation training clinics were categorized into three groups. The official websites of each hospital within the group were individually reviewed to gather information on anesthesiology specialist physicians who serve as department managers in the anesthesiology and reanimation clinics. The quantity of male and female anesthesiology department managers in each group was computed and thereafter compared between the groups.
Results: An analysis of the gender distribution among anesthesiology department managers in hospitals with training clinics revealed that 54% were male and 46% were female. There was no difference in the gender distribution between the three categories based on the analysis of data from a total of 100 institutions (p>0.05).
Conclusion: In 2023, the proportion of female anesthesiologists in leadership positions within their respective departments in our country exceeds the reported global average for female anesthesiologists.

Keywords: Gender equity; leadership; anesthesia; academia
Protection of Intellectual Property Rights (IPR) for Batik Mangrove Products in Tanjung Rejo Village, North Sumatera, Indonesia, as an Initiatives to Export Products
Authors: . Sutiarnoto , Lisa Andriati Syarifah , Panjaitan Nismah
Published: October 2023

Intellectual property rights (IPR) encompass a wide range of property rights stemming from the intellectual or creative capabilities of individuals. These rights span various domains, including knowledge, art, literature, and technology, and their creation typically demands investments in the form of effort, time, financial resources, and intellectual labor. The focal point of this research is the safeguarding of IPR pertaining to Mangrove Batik products originating from Tanjung Rejo village, with the ultimate objective of facilitating their exportation. The chosen research methodology for this study is the normative juridical approach, characterized by its descriptive-analytical nature.
The data used in this research comprises both primary and secondary sources, and the analysis primarily employs qualitative methods, given the predominantly descriptive and analytical nature of the data collected. The research findings underscore the concerted efforts aimed at preserving and upholding intellectual property rights for mangrove batik products originating from Tanjung Rejo village, driven by the goal of amplifying the export potential of these culturally significant creations.
Tanjung Rejo village has carved out a reputation as a producer of exceptionally unique and culturally valuable mangrove batik products. However, the continued success and integrity of this product line are challenged by issues such as counterfeiting and a general lack of awareness regarding intellectual property rights. To address these challenges, this study has initiated an education and training program designed to enhance the local community's comprehension of IPR intricacies and the requisite procedures for exporting these distinct products.
The study's data analysis involves pre-tests and post-tests, which serve as instruments to gauge the effectiveness of the educational program. Encouragingly, the results demonstrate a noteworthy enhancement in the local community's comprehension and awareness of intellectual property rights. This newfound knowledge and understanding can substantially fortify the protection of Mangrove Batik products while concurrently fostering their potential for export. Ultimately, safeguarding intellectual property rights stands as a pivotal instrument in preserving the authenticity and economic worth of this culturally significant product, all the while advancing cultural preservation and stimulating local economic growth.

Keywords: Intellectual Property Rights Protection, Mangrove Batik, Tanjung Rejo Village.
Ultrasound Diagnostic of Torsion of Omental Lymphangioma in a Child with Intestinal Intussusception
Authors: Olkhova E. B. , Topolnik M. V. , Allakhverdiev I. S.
Published: October 2023

Torsion of omental lymphangioma is a extremely rarity, the echographic picture is nonspecific (thin–walled cystic formation) and the diagnosis in the vast majority of cases is made only intraoperatively. It is almost never possible to reliably visualize actually torsion in the form of a whirlpool-sign. The article presents our own observation of the torsion of lymphangioma of the greater omentum in a 2-year-old girl. The onset of the disease was associated with the occurrence of intestinal intussusception, during the diagnosis of which, as a «random finding», a cystic formation of the abdominal cavity was revealed. The child underwent repeated ultrasound and CT scans, which made it possible to reliably visualize the torsion of the cystic formation. The final diagnosis was made intraoperatively. The clinical observation is illustrated by ultrasound and radiologic scans and intraoperative images. The publication is supplemented with a brief review of the literature.
In vitro Antiglycation Activity of Isorhamnetin on Bovine Serum Albumin with different sugars using Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis
Authors: A Sindhuja , R Vimalavathini , Velu V Kuzhandai , V Vickneshwaran
Published: October 2023

Advanced glycation end products (AGEs) resulting from glycation of proteins, lipids and nucleic acids has several pathophysiological manifestations by altering the structure and functions of molecular proteins. Isorhamnetin is a flavonoid with anti-inflammatory, anti-oxidant, anti-obesity, anticancer, antidiabetic and anti-atherosclerosis activity. Based on the structure activity relationship and our insilico antiglycation study of isorhamnetin, we hypothised that isorhamnetin may have antiglycation activity by inhibiting protein glycation on sugar molecules due to its antioxidant and free radical scavenging activity. Hence our aim of the study was to determine the glycation level of bovine serum albumin (BSA) with varying sugar concentration of glucose, fructose and ribose on 14th and 21st day of incubation. Our second objective of the study was to determine the antiglycation activity of isorhamnetin on BSA using all the sugars at 14th and 21st day of incubation using SDS - PAGE. Our study showed that increase in concentration of glucose, fructose and ribose (0 – 50mM) showed a dose dependent decrease in migration of protein implying increased glycation of BSA. Isorhamnetin (100µM) exhibited antiglycation activity for fructose (30mM) at 14th day onwards and for glucose (30mM) was at 21st day onwards. But isorhamnetin did not exert antiglycation activity for ribose (30mM) on both 14th and 21st day of incubation. Our study establishes the antiglycation activity of isorhamnetin however further invivo studies are necessary to warrant this activity.
Prevention of Psychological Stress Induced-Ulcer in rats Treated with Fruit Extract of Gymnospora montana
Authors: B. Kotade Kiran , N. Hiremath Shivanand , Ghule Santosh , Sharma Praveen , Rajput Tanvirsingh , B. Dhamak Kiran
Published: October 2023

Gymnosporia montana (Roth) Bemth. is a traditional herbaceous plant of Celastraceous family found in different regions of India. We have earlier reported its antiulcer activity in aspirin-induced, pylorus-ligation induced, and cysteamine-induced ulcer models. As stress-induced ulcer amount to a majority of clinically evident ulcers, it was thought worthy to investigate the effects of the ethanolic extract of Gymnosporia montana in stress-induced ulcer paradigm. Psychological stress was produced by intra-species emotional communication in a jumping box. Rats were randomly divided into two groups; one was used as the ‘sender’ group that received electrical foot shocks of 10 s duration with 50 s intervallic current for the shock was increased stepwise from 10mA to 25mA. The animals showed emotional responses such as abnormal squealing and jumping. The other group called the ‘responder’ group were able to observe the ‘sender’ group mice but were not subjected to the shocks. A separate group of sender rats was used on each day. The receiver group was exposed to sender group for three consecutive days at the end of which, they were sacrificied and were observed for the presence of gastric lesions. Separate groups of rats were treated half an hour before with Ethanolic extract (500mg/kg, p.o.) and diazepam (5mg/kg, p.o.) and the protocol was repeated. At the end the ulcer index, pH of gastric contents and gastric volume was determined. Further, hisotopathology was also performed. Results revealed a good anti-ulcer activity which was comparable to that of diazepam. In conclusion, the present study affords a significant contribution in confirmation of the forklore effects of a traditional remedy.
Understanding the Global Transmission and Demographic Distribution of Nipah Virus (NiV)
Authors: Ahmed Mahedi Md. Rezwan , Rawat Anurag , Rabbi Fazle , Babu K. Suresh , Tasayco Elias SALVADOR , Ore Areche Franklin , Pacovilca-Alejo Olga Vicentina , Corilla Flores Denis Dante , Vivanco Aguilar Salomón , L. Orosco Fredmoore , Syrmos Nikolaos , Mudhafar Mustafa , Afrin Sadia , Rahman Mst. Mahfuza
Published: October 2023

Nipah virus (NIV) infection was identified in 1998, in Malaysia. The virus belongs to the Paramyxoviridae family. In the past, the virus was spread in Bangladesh, India, as well as Singapore. It affects our nervous system and the respiratory system, which is highly dangerous for our lives. It is caused by an RNA virus and has a high mortality rate. This virus can be transmitted from bats to humans, pigs to humans, or humans to humans. It is conceptualized that fruit bats like Pteropus vampyrus and Pteropus hypomelanus are responsible for transmitting the virus. From 1999 to 2022, there is no approved vaccine and medicines for the treatment of nipah virus infection. The fatality rate of this nipah virus is 75% to 95%. Moreover, NiV B (Bangladesh) is more deathly than NiV M (Malaysia). In present, some vaccines are under trial on pigs, horses and the monkey. In this review we try to focus on the barrier of vaccine and medicine development for this nipah virus.
In vitro and In vivo Study of Gastroprotective effect of Purified Extract Andrographis paniculata
Authors: Pusmarani Jastria , Dewi Citra , Juliansyah Putri Risky , Awaliyah Halid Nur Hatidjah , Intan Febriani Sasri , Husni Febrianti , Purwono Setyo , Ikawati Zullies
Published: October 2023

Gastric ulcers are caused by excessive gastric acid secretion, alcohol, and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin is one of the NSAIDS that can induce peptic ulcers. Traditional medicines that have been proven to have gastroprotective activity is Andrographis paniculata (APAC). The purpose of this study is to assess the antioxidant activity and gastroprotective effect of purified extract of APAC. The herbal treatment was given for 7 days, and on the eighth day, all groups except the negative control (Na CMC 0.5%) were given 1000mg/kgBW of aspirin. Six hours later, the rats were sacrificed and opened for macroscopic examination, pH gastric juice value, the volume of gastric value, ulcer index, and inhibition percentage. Antioxidant studies using 2,2-diphenyl-1-picrylhydrazyl (DPPH) showed that APAC has strong antioxidant activity with IC50 value = 64.54. APAC could reduce the occurrence of gastric ulcers by decreasing gastric pH, ulcer index, and increasing inhibition percentage (P=0.000<0.05). Andrographis paniculata has gastroprotective properties associated with antioxidant activity.
Design, Synthesis and Therapeutic investigation of Tryptamine derivatives as Potential Antioxidant and Amyloid inhibitor/disaggregator
Authors: Asghar Saira , Mushtaq Nousheen , Ahmad Ahsaan , Munawwar Rabya , Ansari Sumaira , Abiha Rizvi Syeda
Published: October 2023

Oxidative stress is one of the main causative factors for pathogenesis of numerous disorders including psychological and neurodegenerative diseases (Alzheimer’s disease and Parkinsonism). Amyloid aggregates induced oxidative stress is involved in disfunction and degeneration of brain cells in Alzheimer’s disease. Antioxidants are important natural or synthetic molecules having tendency to curb free radicals and discontinuing their chain reactions prior to the damage of essential biomolecules. Drugs possessing antioxidant activity are being extensively anticipated for developing novel therapeutic agents in numerous pathological conditions accompanying oxidative stress like AD. In this study twelve tryptamine derivatives were synthesized and investigated for antioxidant, fibril inhibition and disaggregation potential. In vitro antioxidant potential of the derivatives was examined by using DPPH (2,2‑diphenyl‑1‑picrylhydrazyl) assay and revealed that SR10, SR14, SR23 and SR42 displayed better antioxidant activity (IC50 in the range of 0.75±0.05µM-14.43±0.77µM) than the standard ascorbic acid (IC50 =15.83±0.88µM). In vitro amyloid fibril inhibition and disaggregation assay was carried out by using HEWL (Hen egg white lysozyme) presenting moderate to high inhibition/disaggregation activities. Molecular dockingassessment recognized themode of bindingswithin active site of human antioxidant enzyme peroxiredoxin (PDB ID: 3MNG). These tryptamine derivatives with potential antioxidant and inhibition/disaggregation activitieswill be beneficialto develop and designdrug molecules forneurodegenerative disorders.
АЛГОРИТМ РАЗРАБОТКИ ПРОТОКОЛА ОЦЕНКИ БЛАГОПОЛУЧИЯ КОСЯЧНЫХ ЛОШАДЕЙ
Authors: Тулобаев А.
Published: October 2023

Цель исследования – определить алгоритм разработки протокола оценки благополучия косячных лошадей. Объектом исследований был косяк кыргызской аборигенной породы лошадей. Исследования были проведены в фермерских коневодческих хозяйствах Кыргызской Республики, где преимущественно применяется круглогодовое пастбищное содержание лошадей с применением косячной технологии. Методами исследований были сравнительный и системный анализы. Результаты. Для разработки протокола оценки благополучия косячных лошадей был принят алгоритм, состоящий из 6 пунктов. Выбрана и обоснована стратегия разработки протокола; определена концепция протокола оценки благополучия косячных лошадей; уточнены и адаптированы принципы, критерии и показатели протокола благополучия; определены типы измерений; разработаны системы подведения итогов; определены основные положения «Правовых аспектов и ответственности» при оценке благополучия косячных лошадей. В результате исследований выработан макет протокола, состоящий из 3-х принципов благополучия, 7-и критериев благополучия и 20-и показателей оценки благополучия.
ВЛИЯНИЕ МИНЕРАЛЬНЫХ УДОБРЕНИЙ НА СОСТАВ ПОЧВЫ СЕНОКОСА
Authors: Тебердиев Далхат , Чуйков Виктор , Родионова Анна , Запивалов Сергей
Published: October 2023

Влияние длительного применения минеральных удобрений на накопление тяжелых металлов в различных по составу почвах является актуальной проблемой в Нечерноземной зоне России. Основной задачей исследований, проводившихся в ФНЦ «ВИК им. В.Р. Вильямса», являлось определение влияния длительного использования минеральных удобрений на агрохимические показатели почвы, накопление тяжелых металлов. Систематическое применение минеральных удобрений на дерново-подзолистой суглинистой почве сенокоса в течение 74 лет не оказало отрицательного действия на ее агрохимические показатели. Напротив, возросло содержание органического вещества на 30–40 % по вариантам опыта. Снизилась кислотность почвы с рН 4,3 до 4,5–5,3. Содержание токсичных элементов (кадмия, свинца) характеризовалось равномерностью их распределения по горизонту 0–20 см.
ПРОБЛЕМА АНТИБИОТИКОРЕЗИСТЕНТНОСТИ В ЖИВОТНОВОДСТВЕ КЫРГЫЗСКОЙ РЕСПУБЛИКЕ
Authors: Джунушова А. , Темирова Д. , Мадумаров А.
Published: October 2023

Использование антимикробных препаратов в медицине показало хорошие результаты, в следствие чего их стали активно использовать в различных сферах сельского хозяйства. Одной из таких сфер стало и животноводство, используются антибиотики не только для лечения, но и для профилактики инфекционных заболеваний, а также в качестве стимулятора веса и роста. Эффективность животноводства возросла, но вопрос относительно пользы антимикробных препаратов в сельском хозяйстве остается открытым. В мировом сообществе преобладает тенденция отказа и снижения проблемы резистентности к антибиотикам, меняется структура рынка их реализации и разрабатываются новые решения на замену. Распространению резистентности способствует и то, что возросла доступность антимикробных препаратов для населения, а также все более активное перемещение животных, обмен продуктами питания, а с ними – и устойчивыми микроорганизмами. В статье поднимается актуальная тема нерационального использования антибиотиков и растущей резистентности к антибиотикам и изложен материал опроса среди ветеринарных врачей, фермеров и персонала по уходу за животными, о последствиях бесконтрольного применения антибиотиков в ветеринарной практике и животноводстве, а также формирования антибиотикорезистентности бактерий и последствиях для организма человека.
ВЛИЯНИЕ ВКЛЮЧЕНИЯ ПРЕМИКСОВ В КОМБИКОРМА ПОРОСЯТ ПРИ ДОРАЩИВАНИИ НА ИНТЕНСИВНОСТЬ ИХ РОСТА
Authors: Хайновский Александр , Сычева Лариса , Перевойко Жанна
Published: October 2023

В статье представлены результаты изучения роста и развития поросят в период доращивания при включении премиксов в рецепты стартерных и гроуэрных комбикормов. Установлено, что включение премикса KPLE (9892) в дозе 2,5 % в стартерном комбикорме и 2,0 % в гроуэрном комбикормах позволил получить высокий среднесуточный прирост живой массы 421,5 г, высокую сохранность 96,1 %, обеспечить развитие мясного типа телосложения у поросят-отъемышей.
ВЛИЯНИЕ ПОРОДНОЙ ПРИНАДЛЕЖНОСТИ БЫЧКОВ НА СОРТОВОЙ СОСТАВ МЯСНОЙ ПРОДУКЦИИ
Authors: Толочка Василий , Гармаев Баир , Гармаев Дылгыр , Косилов Владимир , Никонова Елена , Рахимжанова Ильмира
Published: October 2023

В статье представлены результаты оценки влияния генотипа бычков мясных пород на сортовой состав съедобной части туши и морфометрические показатели длиннейшей мышцы спины. Целью исследования являлось определение выхода мяса высшего, I и II сорта по колбасной классификации и промеров длиннейшего мускула спины бычков разных генотипов при выращивании в условиях Приморского края. При проведении научно-хозяйственного опыта бычки всех подопытных групп содержались в одинаковых условиях при полноценном, сбалансированном по всем питательным, минеральным веществам и энергии рационе кормления. Установлено влияние генотипа бычков на сортовой состав съедобной части туши и промеры мускула. При этом бычки калмыцкой породы уступали абердин-ангусам и герефордам по абсолютной массе мяса высшего сорта соответственно на 3,11 кг (15,84 %) и 3,31 кг (16,86 %), относительной – на 0,4 % и 0,2 %, мяса I сорта – на 6,52 кг (14,56 %) и 7,26 кг (16,21 %), 0,4 % и 0,2 %. В то же время бычки калмыцкой породы, уступая сверстникам абердин-ангусской и герефордской пород по абсолютной массе мяса II сорта, на 3,98 кг (10,98 %) и 5,21 кг (14,38 %) превосходили их по относительной массе мяса этого сорта на 0,8 % и 0,4 % соответственно. Бычки абердин – ангусской и герефордской пород превосходили калмыцких сверстников по развитию длиннейшей мышцы спины, о чем свидетельствует величина промеров ее глубины, ширины и площади на поперечном разрезе.
ГЕНЕТИЧЕСКОЕ ВЛИЯНИЕ КОРОВ-ПЕРВОТЕЛОК НА ФИЗИКО-ХИМИЧЕСКИЕ ПОКАЗАТЕЛИ МОЛОЧНОЙ ПРОДУКЦИИ
Authors: Кадралиева Бакытканым , Рахимжанова Ильмира , Миронова Ирина , Чернышенко Юлия
Published: October 2023

Анализ полученных данных свидетельствует, что уровень физико-химических показателей во многом обусловлен генотипом коров-первотелок.  Содержание жира в молоке является одним из важнейших контролируемых показателей. Полученные нами данные и их анализ свидетельствуют о генетической детерминированности этого важнейшего признака, оказывающего существенное влияние на пищевую и энергетическую ценность молока. Установлено, что максимальным содержанием жира в молоке отличались помесные животные IV и V групп, минимальным – чистопородные коровы-первотелки II и III групп, чистопородные сверстницы черно-пестрой породы I группы занимали промежуточное положение. Полученные нами экспериментальные материалы и их анализ свидетельствуют о влиянии генотипа коров-первотелок на содержание белка в молоке. молоко коров-первотелок всех генотипов отличалось высокими качественными характеристиками, пищевой и энергетической ценностью. Результаты исследования свидетельствуют о положительном влиянии скрещивания черно-пёстрого и голштинского скота на минеральный состав молока помесей. Полученные данные свидетельствуют, что при скрещивании коров черно-пестрой породы с голштинами немецкой селекции отмечалось промежуточное наследование признака (содержание лактозы в молоке). При этом скрещивание животных черно-пестрой и голштинской пород способствовало повышению физико-химических свойств молока помесных коров-первотелок IV и V групп.
БИОЭКОЛОГИЧЕСКИЕ ОСОБЕННОСТИ И РАЙОНЫ РАСПРОСТРАНЕНИЯ ПЕРСИКОВОЙ ПЛОДОЖОРКИ CARPOSINA NIPONENSIS W.1900 НА ТЕРРИТОРИИ КЫРГЫЗСТАНА
Authors: Адылмырзаева Канайым , Муратова Рахима , Эрматова Венера , Дуйшеналиев Жакшылык
Published: October 2023

В данной работе впервые описано и идентифицирован вид под карантинного вредителя персиковой плодожорки Carposina niponensis W. 1900 и предварительно прогнозирован их дальнейшее географическое распространение по другим районам республики. В условиях Кыргызстана установлено массовое вывешивания ферамонных ловушек для определение очагов и динамики лета под карантинного вида персиковой плодожорки. На основании проведенных обследований составлена карта прогноза их дальнейшего распространения вредителя.
ПРОИЗВОДСТВО И ПЕРЕРАБОТКА КОЗЬЕГО МОЛОКА ИЗ ВЫСОКОКРОВНЫХ КОЗ АЛЬПИЙСКОЙ ПОРОДЫ
Authors: Косимов Матазим , Хамзаев Ботир , Абдурахмонов Мазбут
Published: October 2023

В статье приводится производство и переработка козьего молока, технологических свойств молока и состояние молочного козоводства в Северном Таджикистане. Дается характеристика продуктивности высококровных помесей альпийского породы.
ГОРМОНАЛЬНЫЙ СТАТУС И ОСНОВНЫЕ ПОКАЗАТЕЛИ СПЕРМОПРОДУКТИВНОСТИ БЫКОВ-ПРОИЗВОДИТЕЛЕЙ ОТЕЧЕСТВЕННЫХ МОЛОЧНЫХ ПОРОД
Authors: Ушакова Светлана , Машталер Д. , Мороз Татьяна , Приданова Ирина , Ерохина Н.
Published: October 2023

Исследован гормональный статус, а также показатели спермопродуктивности быков-производителей отечественных молочных пород: костромской, ярославской, холмогорской. Определен уровень стероидных гормонов: тестостерона, эстрадиола и кортизола, а также содержание тиреоидного гормона тироксина. Кровь отбирали у здоровых быков в день взятия семени (через 30 мин). Содержание гормонов определяли в сыворотке крови. Образцы исследовали на анализаторе иммуноферментных реакций «Униплан» с помощью лабораторных реагентов (ЗАО НВО «Иммунотех», Россия). Было установлено, что имеется значительная вариабельность в содержании эндогенных гормонов в сыворотке крови у быков-производителей, что может быть обусловлено как средовыми факторами, так и индивидуальными особенностями быков.  У быков ярославской породы, в нашем исследовании, отмечен самый высокий уровень тестостерона - 38,3±11,26 нмоль/л, а также самый большой объем эякулята 3,33±0,27 мл.
Phytochemical Screening, Characterization of Bioactive Component from Plant Phragmites Karka (Retz.)Trin Ex Steud.and its Biological Evaluation with Reference to Wound Healing Activity
Authors: Shagufta khan, Harsha Parihar, Anjali Peter, Nuzhat Qureshi
Published: October 2023

Skin repair is a complex, multi-step biological process that requires close contact among several cell types in a well-synchronized system. Recent research has improved our understanding of the particular intervention of distant stem cells originating from distant tissues like bone marrow to enable cutaneous repair. This information's conclusion will focus briefly on three issues of great concern: scarring, tissue engineering for skin wound healing, and plasma application.
Cooling down the world oceans and the earth by enhancing the North Atlantic Ocean current
Authors: Hunt Julian David
Published: October 2023

The world is going through intensive changes due to global warming. It is well known that the reduction in ice cover in the Arctic Ocean further contributes to increasing the atmospheric Arctic temperature due to the reduction of the albedo effect and increase in heat absorbed by the ocean’s surface. The Arctic ice cover also works like an insulation sheet, keeping the heat in the ocean from dissipating into the cold Arctic atmosphere. Increasing the salinity of the Arctic Ocean surface would allow the warmer and less salty North Atlantic Ocean current to flow on the surface of the Arctic Ocean considerably increasing the temperature of the Arctic atmosphere and release the ocean heat trapped under the ice. This paper argues that if the North Atlantic Ocean current could maintain the Arctic Ocean ice-free during the winter, the longwave radiation heat loss into space would be larger than the increase in heat absorption due to the albedo effect. This paper presents details of the fundamentals of the Arctic Ocean circulation and presents three possible approaches for increasing the salinity of the surface water of the Arctic Ocean. It then discusses that increasing the salinity of the Arctic Ocean would warm the atmosphere of the Arctic region, but cool down the oceans and possibly the Earth. However, it might take thousands of years for the effects of cooling the oceans to cool the global average atmospheric temperature.
Biased agonism in the mu-opioid receptor
Authors: Martinez-Mayorga Karina , Madariaga-Mazon Abraham , Marmolejo-Valencia Andrés
Published: October 2023

Dr. Karina Martinez-Mayorga discuss Biased agonism in the mu-opioid receptor.
Biomimetic Structural Optimization Method: New paradigm for shape and topology optimization
Authors: Nowak Michal
Published: October 2023

The trabecular bone adapts its form to mechanical loads and is able to form lightweight but very stiff structures. In this sense, it is a problem (for the Nature) similar to the structural optimization, especially the topology optimization. The structural optimization system based on shape modification using shape derivative [1] will be presented. Structural evolution during the
structural optimization procedure is based on the adaptive remodeling of the trabecular bone and is independent of domain selection. In general the problem of stiffest design (compliance minimization) has no solution. If the volume of the object is increasing, the compliance is decreasing. Thus, in the
standard approach to the energy based topology optimization the additional constraint has to be added. Usually the volume of the material is limited. But with such an assumption the optimization procedure does not include any criteria for stress. In case of the biomimetic approach presented here, the role of the additional constraint plays the strain energy density on the structural surface (which is between two assumed levels forming the insensitivity zone) and the volume or structural mass results from the optimization procedure. The variational approach to shape optimization in linearized elasticity is used in order to improve convergence of a heuristic algorithm. The method is
enhanced to handle the problem of structural optimization under multiple loads [2]. The new approach does not require volume constraints. Instead of imposing volume constraints, shapes are parameterized by the assumed strain energy density on the structural surface.
Competitive removal of PGMs from aqueous solutions via dendrimer modified magnetic nanoparticles
Authors: Malgas-Enus Rehana
Published: October 2023

Competitive adsorption of Au(III)- Pd(II)-, and Pt(IV)-chlorido species were carried out using generation 3 diaminobutane poly(propylene) imine dendrimer micelle (G3-DM15) and palmitic acid (C15-acid) modified superparamagnetic iron oxide nanoparticles (SPIONs). The efficacy of the adsorbents in the recovery of the three metal chlorido species were tested by varying the solution pH and the contact time. SPIONs modified with both the G3-DM15 and C15-acid were not only stable in very acidic conditions (compared to the unmodified SPIONs) but also selective to Au(III)-Cl species with percentage efficiencies of more than 98%. The adsorption of the three metal chlorido species onto the four adsorbents obeyed the Langmuir isotherm. The unmodified SPIONs (ADS 1) and dendrimer modified SPIONs (ADS 2 and ADS 4) gave the highest maximum adsorption capacities for Au(III)-Cl species [17.07 mg g−1 (ADS 1), 6.48 mg g−1 (ADS 2) and 8.31 mg g−1 (ADS 4)] compared to SPIONs modified with only C15-acid (ADS 3) (1.17 mg g−1). The adsorption kinetics were evaluated using three kinetic models; pseudo-first-order, pseudo-second-order and intraparticle diffusion. The adsorption kinetics for all the three metal chlorido species best fitted the pseudo-second-order kinetics model. Desorption studies showed that all three metal chlorido species can be recovered from the adsorbents.
Classification of COVID-19 Symptoms Using Multilayer Perceptron
Authors: Azam Nurulain Nusrah Mohd , Ismail Mohd Arfian , Mohamad Mohd Saberi , Ibrahim Ashraf Osman , Jeba Shermina
Published: October 2023

The COVID-19 virus had easily affected people worldwide through direct contact. Individuals
diagnosed with positive COVID-19 virus may be affected with many symptoms, such as fever, tiredness, dry cough,
difficulty in breathing, sore throat, chest pain, nasal congestion, runny nose, and diarrhea. An individual can also
be diagnosed with COVID-19 even when he does not have any symptoms or be in contact with an infected person.
Data classification was required due to the size of COVID-19 data that will be analyzed for future countermeasures
determination. Some problems in data classification occurred due to unorganized data, such as time consumption,
human error in complexity of symptom features and the diagnosis process data needed expert knowledge. This study
aimed to use the artificial neural network (ANN) approach, which was multilayer perceptron (MLP) to classify the
COVID-19 data by using patient symptom data. The MLP process involved data collection, data normalization, MLP
design, MLP training, testing, and MLP verification. From the experiments, the MLP method was able to obtain
an accuracy rate of 77.10%. In conclusion, the MLP method could classify the COVID-19 data and achieve a high
accuracy rate
Stevens: The Unreliable Narrator in Kazuo Ishiguro’s The Remains of The Day
Authors: Deepa
Published: October 2023

Kazuo Ishiguro, an eminent figure in contemporary literature, crafts narratives distinguished by their nuanced, restrained characters. One of his most profound works, The Remains of the Day (1989), offers readers a masterclass in the art of subtle storytelling. Central to this novel is the depiction of the protagonist, Butler Stevens, an embodiment of Ishiguro’s knack for blending subtlety with complexity. Stevens stands as a hallmark of Ishiguro’s imaginative prowess, serving as an intricate reflection of an era gone by. This character’s unyielding dedication to his profession, as reflected in the ideals of “Butler’s dignity,” not only encapsulates his identity but also becomes the lens through which he views the world. Yet, as the narrative unfolds, this seemingly unshakeable commitment is juxtaposed against Stevens’ personal introspection during a brief hiatus from his professional realm. This period of introspection proves revelatory, unearthing memories, regrets, and truths previously buried beneath the veneer of his professional demeanor. The novel expertly ‘compels’ its readers to discern the actuality behind the events depicted and, simultaneously, beckons them into the emotional depths of Stevens’ responses. As Stevens delves into the annals of his past, a realization dawns upon him: there are moments of folly, instances of misled loyalty, and actions driven by misconceptions. While he had dedicated his life to the grandeur of Darlington Hall, this commitment had come at the expense of personal fulfillment and genuine human connections. Towards the novel’s denouement, a poignant sense of regret permeates Stevens’ psyche. The culmination of this sentiment is his acknowledgment of certain truths and the unreliability of his own narration. This unreliable narration isn’t just a literary device but serves as a mirror to Stevens’ internal conflict, revealing the dichotomy between his perceived duties and suppressed emotions. Thus, The Remains of the Day is not just a tale of loyalty and duty but an exploration of the human soul, its vulnerabilities, and the intricate web of memories and emotions that define us.
Distribution of the gill parasite Discocotyle sagittata (Monogenea: Polyopisthocotylea) in parr of Atlantic salmon Salmo salar and sea trout S. trutta in Norwegian rivers
Authors: Mo Tor Atle
Published: October 2023

The monogenean gill parasite Discocotyle sagittata is reported from parr of Atlantic salmon Salmo salar and sea trout S. trutta in the anadromous part of 86 out of 223 Norwegian rivers. The prevalence in each river varied from 1.5% to 88.9%. This study has significantly increased our knowledge about the occurrence of this salmonid parasite in Norway. Most likely, D. sagittata has a much wider distribution all over the country and probably also occur in numerous inland lakes, rivers and streams.
A 33 year old with 21 years psychological dependence on tracheostomy who was successfully decanulated with a simple method: A case report
Authors: Folorunso DF  , Dahilo AE  , Adeyi MO  , Damtong MF  , Oyeleye BF  , Omosule I A  , Etukumana IA  , Dauda RR  , Onoja WA  , Ochi CC  , Ibekwe TS
Published: October 2023

Background: Psychological dependence on tracheostomy is ubiquitous among children and very young. Case: We report a case of a 33year old who had tracheostomy for recurrent respiratory papillomatosis 21years ago, Efforts at decannulation through simple and surgical methods failed leaving her on a permanent tracheostomy and psychological dependency for over 2 decades The patient presented to our clinic and following evaluation, it was realize that apprehension and loss of self confidence was a major factor. she was engaged in medical,social and psychological counseling prior to this 4th trial at decannulation,when it was realized she was stable enough and psychologically ready. A simple decannulation method focusing mainly on close monitoring of vital signs, especially oxygen saturation rather than somatization features of patients due to exaggerated anxiety and fear which appears to be largely a factor in the previous failed attempt at decanulation. interestingly, the patient tolerated the decanulation trial and final decannulation. she has been stable and off tracheostomy for the past 6months
Aproveitamento da farinha de casca de mandioca na elaboração de pão de forma
Authors: Vilhalva Divina Aparecida Anunciação , Soares Júnior Manoel Soares , Moura Camila Melo Araújo de , Caliari Márcio , Souza Thaísa Anders Carvalho , Silva Flávio Alves da
Published: October 2023

Nas indústrias de mandioca são produzidos grandes volumes de resíduos sólidos (cascas e bagaço). A viabilidade de aproveitamento da farinha de casca de mandioca (FCM) para o consumo humano foi pesquisada, como substituto parcial da farinha de trigo (FT) na elaboração de pães de forma. Delineamento inteiramente aleatório foi utilizado, efetuando-se cinco tratamentos e quatro repetições originais. O tratamento com 7,5% de substituição de FT por FCM resultou em maior volume específico (4,78 cm3 /g) entre os procedimentos com FCM. A luminosidade (L*) variou de 64,92 a 11,54 e a cromaticidade (a*) entre 0,78 e 7,58, com escurecimento do miolo com o aumento do nível de substituição de FT por FCM. Todos os tratamentos apresentaram teores mais elevados de fibras e mais baixos de carboidratos do que o pão controle. A aceitação dos pães de forma com diferentes taxas de substituição de FT por FCM foi satisfatória e todos os atributos avaliados receberam escores médios acima de 6,72. Os pães com até 15% de substituição de FT por FCM não diferiram do tratamento controle quanto ao aroma, textura e sabor, que fortalecem a constituição de uma alternativa viável de inclusão de um produto contendo alto teor de fibras no Mercado.
Dinâmica microbiana em contrafilés bovinos embalados a vácuo: sistemas de terminação e tempo de estocagem
Authors: Melo Camila Silveira de , Mesquita Albenones José de , Minafra-Rezende Cíntia Silva , Seraphin José Carlos , Oliveira Marinna Barros de , Bueno Cláudia Peixoto
Published: October 2023

A qualidade da carne embalada a vácuo é de grande importância para o comércio. Neste contexto, no presente estudo foi avaliada a dinâmica microbiana de cortes cárneos bovinos Longissimus dorsi, denominado comercialmente por contrafilé, embalados a vácuo e armazenados a 0 ± 1 °C no estabelecimento de abate durante cinco períodos de estocagem. Foram analisadas amostras de cortes cárneos provenientes de bovinos anelorados, fêmeas, terminados em dois sistemas de produção, sendo 15 adultos criados a pasto, com média de 45 meses de vida e 15 bovinos jovens de 12 meses de idade em confinamento de alto desempenho. Procedeu-se a avaliação bacteriológica das carnes nos períodos de tempo correspondentes à zero, 30, 45, 60 e 75 dias após o abate e embalagem. A avaliação microbiológica foi efetuada pela contagem de aeróbios viáveis, bactérias ácido lácticas, Enterobacteriaceae, psicrotróficos, anaeróbios, determinação do Número Mais Provável (NMP) de coliformes totais, coliformes termotolerantes e Escherichia coli, análise de pH e temperaturas dos cortes. O sistema de terminação influenciou parcialmente na dinâmica microbiana. As carnes embaladas a vácuo podem apresentar micro-organismos deteriorantes e patogênicos, provenientes de contaminação ambiental ou fecal. Quanto maior o período de estocagem dos cortes cárneos, a contagem de micro-organismos avaliados foi maior.
Ocorrência de Cronobacter spp. (Enterobacter sakazakii) em alimentos infantis adquiridos em um hospital público
Authors: Freitas Luciana Giorgetti , Ristori Christiane Asturiano , Jakabi Miyoko , Paula Ana Maria Ramalho de , Rowlands Ruth Estela Gravato
Published: October 2023

Cronobater spp. (E. sakazakii) é considerada um micro-organismo oportunista que vem ganhando atenção de autoridades de Saúde Pública, pelo crescente número de surtos de infecção em recém–nascidos e lactentes. A bactéria está associada a casos raros, com alta taxa de mortalidade, podendo causar meningites, enterocolite necrosante e septicemia. Cronobacter spp. tem ampla disseminação, porém apenas as fórmulas lácteas infantis em pó foram, epidemiologicamente, associadas às doenças causadas por esse agente. No presente estudo foi avaliada a ocorrência de Cronobacter spp. em alimentos destinados às crianças de 0-36 meses de idade, adquiridos em lactário de um hospital público do município de São Paulo. Vinte e seis amostras de fórmulas reconstituídas e 24 produtos em pó foram analisados segundo a metodologia da ISO. Cronobacter spp. foi detectada em uma amostra (3,8%) reconstituída de alimento infantil à base de farinha de milho e em quatro desse produto em pó (16,7%). A bactéria não foi detectada nas fórmulas infantis destinadas às crianças de 0-6 meses, contudo sua presença em outros alimentos infantis pode contribuir para a contaminação do ambiente e dos utensílios dos lactários por meio da contaminação cruzada.
Propriedade antimicrobiana do eugenol frente às amostras de Alicyclobacillus spp. isoladas de suco de laranja
Authors: Oliveira Juliana Guerra de , Abreu Filho Benício Alves de
Published: October 2023

Foi avaliada a atividade antimicrobiana do eugenol contra Alicyclobacillus hesperidum, Alicyclobacillus cycloheptanicus, Alicyclobacillus acidiphilus, Alicyclobacillus acidoterrestris e de Alicyclobacillus spp., isolados em indústrias de sucos de laranja de várias regiões do Estado de São Paulo. O teste de suscetibilidade para o eugenol foi realizado determinando-se a concentração inibitória mínima (CIM) pela técnica de microdiluição em placas de 96 cavidades. A CIM do eugenol variou de 66,65 a >1066,4 μg/mL, evidenciando-se a atividade inibitória forte e moderada frente a todas as amostras testadas e a atividade bactericida. Este estudo demonstrou ser significativa a fonte de isolamento das linhagens de Alicyclobacillus spp. nas indústrias. Conclui-se que o eugenol possui eficaz atividade antimicrobiana contra Alicyclobacillus spp. e sugere-se o uso deste composto para prevenir a deterioração de bebidas acidificadas e para diminuir o custo do controle microbiológico mais especificamente em suco de laranja.
Influência do uso de cultura adjunta nas características físico-químicas e sensoriais do queijo tipo Camembert
Authors: Dias Geruza , Tavares Guilherme Miranda , Carvalho Antônio Fernandes de , Furtado Mauro Mansur
Published: October 2023

O presente estudo avaliou o efeito da adição do Geotrichum candidum, como cultura adjunta, na aceitação e composição do queijo tipo Camembert. O leite utilizado na fabricação dos queijos foi submetido à pasteurização e adicionado de Lactococcus lactis subsp. Lactis e Lactococcus lactis subsp. cremoris. Foram realizados quatro tratamentos: controle (T1) – sem adição de Geotrichum candidum; e T2, T3 e T4, com concentrações, respectivamente, de 0,5 U, 1 U e 1,5 U do microorganismo. Após 1, 9, 17, 25, 33 e 41 dias de fabricação, os queijos foram avaliados quanto aos parâmetros: acidez, pH, proteína, NS a pH 4,6, NS em TCA 12%, umidade, e para gordura e sal no queijo com um dia de preparação. A análise de aceitação foi realizada aos 30 dias de maturação. Os queijos com e sem adição de Geotrichum candidum não diferiram (P > 0,05) nas análises físico-químicas. Os quatros tratamentos diferiram (P < 0,05) em todas as análises no decorrer do tempo de maturação. Com o aumento na concentração do Geotrichum candidum, houve aumento na média de aceitação dos provadores. A utilização do Geotrichum candidum é uma boa alternativa para as indústrias que desejam um produto com boa aceitabilidade e características semelhantes ao tradicional queijo Camembert.
Solução alternativa coletiva de abastecimento de água (SAC): avaliação da qualidade bacteriológica e da cloração
Authors: Teixeira Inara Siqueira de Carvalho , Peresi Jacqueline Tanury Macruz , Silva Sonia Izaura de Lima e , Ribeiro Aparecida Klai , Graciano Rejane Alexandre Silva , Povinelli Rodrigo Friozi , Santos Cecília Cristina Marques dos
Published: October 2023

As águas de soluções alternativas coletivas de abastecimento (SAC) nos municípios situados no noroeste do estado de São Paulo foram avaliadas quanto à qualidade bacteriológica e ao teor de cloro residual livre (CRL), de acordo com a Portaria nº 518 do Ministério da Saúde. Entre 2004 e 2010, foram analisadas 3.564 amostras de 66 municípios da área de abrangência do Grupo de Vigilância Sanitária 29 – São José do Rio Preto (GVS 29 – SJRP-SP) e de 26 municípios do GVS 30-Jales. Das amostras em desacordo (1.775) da região de abrangência do GVS 29 – SJRP-SP, observou-se que 1.201 (67,7 %), 1.107 (62,4 %) e 256 (14,4 %) foram não conformes, respectivamente, em pelo menos um dos seguintes parâmetros: CRL, coliformes totais e C. termotolerantes/Escherichia coli. Quanto às amostras em desacordo da região do GVS 30-Jales (317), os números foram: 104 (32,8%), 257 (81,0%) e 82 (25,9%). Considerando-se a identificação de indicadores de contaminação das águas dos SAC, este estudo fornece subsídios aos serviços de abastecimento de água e de vigilância em saúde para implementar o controle e a prevenção de doenças de transmissão e de origem hídrica e para melhoria das condições e qualidade de vida das comunidades abrangidas.