bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of viral hepatitis infection in India: A systematic review and meta-analysis
Authors: Kumar Dhasarathi , Peter Roshni M. , Joseph Alex , Kosalram Kalpana , Kaur Harpreet
Published: April 2023

BACKGROUND:

Nowadays, Viral Hepatitis can be comparable to the big three communicable diseases: tuberculosis, HIV/AIDS, and malarial infections. The main purpose of this study was to summarize the prevalence of viral Hepatitis in India from peer-reviewed articles published from February 2000 to February 2021.

MATERIALS AND METHODS:

We conducted a systematic search on Science Direct, Scopus, Medline, PubMed, Web of Science, Google Scholar, and other open access journals. We evaluated all relevant papers that looked into the prevalence of viral Hepatitis systematically. Finally, 28 studies on viral Hepatitis published from February 2000 to February 2021 have been selected. These studies have been conducted across the northern, southern, central, eastern, and western regions of India.

RESULTS:

Twenty-eight full-text publications were obtained and evaluated consisting of 45,608 research participants. Hepatitis A was found to range from 2.1% to 52.5%. Hepatitis B was found in a wide range of individuals, ranging from 0.87% to 21.4% of the population. Hepatitis C was found to range from 0.57% to 53.7%. The majority of the children were affected by hepatitis A, and 47.4% of third-trimester pregnant mothers were affected by hepatitis E. Diabetes, hospital admission, history of jaundice, history of surgeries, and heterosexual contact were the leading modes of acquiring HBV and HCV infections. As a result of its great magnitude, this disease poses a severe threat to the national healthcare system.

CONCLUSION:

Effective public health measures are urgently needed to minimize the burden of viral Hepatitis and eliminate the disease.
Pemetaan Kondisi Lingkungan Tanam menggunakan K-Means Clustering sebagai Dasar Sistem Rekomendasi Tindakan Pertanian
Authors: Kholila Ni'ma
Published: April 2023

Objektif. Pemasangan alat IoT-Agri, sebagai sistem pemantauan kondisi lingkungan tanam berbasis Internet of Things, menghasilkan sejumlah besar data rekam kondisi lingkungan tanam. Melalui pendekatan data mining, data rekam yang terdiri dari waktu tanam, pH air, suhu air, suhu udara, dan nilai TDS dapat digunakan untuk memetakan kondisi lingkungan penanaman. Pemetaan selanjutnya dapat digunakan sebagai dasar sistem keputusan tindakan pertanian.

Material and Metode. Pemetaan kondisi lingkungan tanam menggunakan algoritma k-means clustering, diuji menggunakan elbow method dan dijadikan dasar sistem keputusan tindakan pertanian yang dikirimkan melalui telegram bot.

Hasil. Kondisi lingkungan tanam dipetakan dalam 3 (tiga) cluster. Masing-masing merupakan kondisi lingkungan tanam yang kurang nutrisi dan kurang air, cukup nutrisi tapi kurang air, serta cukup nutrisi dan cukup air. Pengujian clustering dengan elbow method menunjukkan bahwa pemetaan Kondisi lingkungan tanam bernilai optimal ditunjukkan dengan nilai inersia sebesar 199,065. Keputusan tindakan pertanian dikirimkan melalui telegram bot berupa instruksi penambahan unsur hara, penambahan air, dan penambahan unsur hara serta air.

Kesimpulan. Data yang diperoleh dari pemasangan alat IoT-Agri dikelola menggunakan pendekatan data mining, dipetakan berdasarkan kecukupan dan/atau kebutuhan lingkungan tanam terhadap nutrisi dan air. Secara efektif, keputusan tindakan pertanian dapat diberikan kepada petani sesuai dengan kondisi lingkungan tanam saat ini.
Researcher’s Reflexivity in a Study of Gender and Vulnerable Children in Eswatini Schools
Authors: Motsa Ncamsile Daphne
Published: April 2023

Qualitative researchers come into the research field embodied with all their background experiences and interpretations of the phenomenon they are studying. These all have a bearing on the study undertaken. Reflexivity therefore becomes imperative, not only in the knowledge and data generating process, analysis, and interpretation but also in legitimizing qualitative studies. This paper explores the significance of reflexivity as a critical and crucial strategy in qualitative studies. I do this by unpacking the partial, positioned, and effective perspectives that I brought into research that sought to explore vulnerable children’s gender constructions in three (3) rural schools in Eswatini. In this paper, I discuss my interactions with the participants – as a connected knower, as well as the emotionally charged interview spaces which might have indeed influenced data generation as well as analysis. I also detail how data generation was not only an emotionally arduous process but, reflecting on the research findings gave me space to think about my preconceived views, which led to the critique and analysis of my own beliefs, views and perceptions on vulnerability and gender. At the same time detailing how my position helped me to critically analyse the research findings from a point of reference in ways that enriched the study aimed at enhancing equitable gender experiences for the vulnerable children in these contexts.
Aksesibilitas Rekam Medis Pasien Covid-19 Pada Rumah Sakit Pemerintah Dalam Perspektif Kearsipan
Authors: Azmi Azmi
Published: April 2023

Rumah sakit pemerintah adalah institusi pelayanan kesehatan milik pemerintah yang menyelenggarakan pelayanan kesehatan perseorangan secara paripurna. Ketika Indonesia terjangkit pandemi Covid-19, rumah sakit pemerintah rujukan Covid-19 (RSPR Covid-19) menjadi institusi terdepan dalam merawat pasien korban Covid-19. Kurang efektifnya penerapan kebijakan pemerintah dalam pencegahan penyebaran Covid-19 dan rendahnya kepatuhan masyarakat mengakibatkan jumlah kasus Covid-19 terus bertambah serta korban yang perlu mendapat perawatan di rumah sakit pun meningkat. Kondisi ini berdampak terhadap meningkatnya jumlah rekam medis pasien Covid-19 (RMP Covid-19) yang harus dikelola RSPR Covid-19. Di tengah kekhawatiran masyarakat terhadap pandemi Covid-19, juga ada kekhawatiran terhadap potensi penyalahgunaan RMP Covid-19 sebagai data/informasi privasi pasien rumah sakit sangat besar. Penelitian tentang Aksesibilitas RMP Covid-19 pada Rumah Sakit Pemerintah dalam Perspektif Kearsipan ini bertujuan untuk mengkaji aksesibilitas RMP Covid-19 sebagai arsip dinamis berkategori rahasia. Penelitian ini menggunakan pendekatan kualitatif dengan metode pengumpulan data yang bersumber dari literatur (studi dokumen). Hasil penelitian menunjukkan bahwa ada keterkaitan antara sistem klasifikasi keamanan dan akses arsip sebagai pedoman akses arsip dinamis dengan pelindungan RMP Covid-19 pada RSPR Covid-19.
Covid-19 y reumatología, un eje importante de PANLAR 2021
Authors: Fajardo Estefanía
Published: April 2023

En PANLAR 2021 se revisará la situación de tres países, así como la vacunación, infección y tratamiento en pacientes con enfermedades reumatológicas.
ACR, EULAR e GRAPPA estão presentes no PANLAR 2021
Authors: Fajardo Estefanía
Published: April 2023

O programa científico inclui simpósios sobre covid-19, artrite psoriática e atualizações.
Covid-19 e reumatologia, um eixo importante do PANLAR 2021
Authors: Fajardo Estefanía
Published: April 2023

PANLAR 2021 fará uma revisão da situação em três países, bem como a vacinação, infecção e tratamento nos pacientes com doenças reumatológicas.
Global Rheumatology: A Commitment to Publish and Disseminate Science
Authors: Fajardo Estefanía
Published: April 2023

Two participations are expected to motivate the publication of research and the correct, pertinent, and adequate use of communication channels for the dissemination of information that contributes to society from the scientific point of view.
Interspecific Contact Scenes: Humans and Street Dogs in the Margins of the City
Authors: Dünne Jörg
Published: April 2023

The main subject of this paper are two recent Latin American films (La mujer de los perros by Laura Citarella and Verónica Llinás, 2015, and Los Reyes by Bettina Perut and Iván Osnovikoff, 2018) that centre on street dogs in marginal urban zones of Buenos Aires and Santiago de Chile. It will be argued that in both films exemplary forms of encounter between humans and dogs outside domestic environments can be examined, exploring the alternative ways of conviviality against the backdrop of the multiple layers of shared history between two companion species. In addition to the detailed analysis of exemplary scenes in both films, the concept of the interspecific “contact scene” (as a variation of the “contact zone”, a concept coined by Mary Louise Pratt) is proposed as a possible tool for the analysis of convivial constellations in Latin America.
“Família” e a nova gramática dos Direitos Humanos no governo de Jair Bolsonaro (2019-2021)
Authors: Moschkovich Marília
Published: April 2023

Este trabalho pretende oferecer evidências de como usos estratégicos da categoria “família” pelo Estado podem funcionar como ferramentas na construção de uma abordagem conservadora dos Direitos Humanos, redesenhando a convivialidade e ao mesmo tempo apagando discursivamente desigualdades ao tratar problemas sociais como questões meramente morais. Para fazer isso, o trabalho analisa o caso do Ministério da Mulher, da Família e dos Direitos Humanos entre os anos de 2019 e 2021, durante o governo de extrema direita de Jair Bolsonaro no Brasil, por meio de uma análise do uso do YouTube pelo ministério junto a um exame de inspiração etnográfica da documentação e legislação disponível em seus canais digitais oficiais no período. As análises são apresentadas em duas seções: (i) a primeira abre o debate teórico refletindo sobre as relações e tensões entre “família” e Estado enquanto uma disputa acerca de como a convivialidade é regulada, num sentido amplo, ressaltando algumas características da categoria “família” nas políticas públicas que podem ter contribuído com o fenômeno analisado; (ii) a segunda seção parte do exame de documentos para discutir como a inserção da categoria “família” no discurso sobre políticas públicas do dito ministério embasou uma disputa própria sobre o sentido de “Direitos Humanos”. Essa segunda seção reflete, ainda, sobre como o foco na “família” parece ser parte de uma tática efetiva para materializar a política anti-Gênero de forma a apagar institucionalmente desigualdades que as políticas públicas de Direitos Humanos buscariam, em tese, atenuar ou resolver.
“¿Cómo se vivió aquí en la pandemia?” La trama convivial de la covid-19
Authors: Pinedo Jerónimo
Published: April 2023

“¿Cómo se vivió aquí en la pandemia?” es la pregunta que organiza esta investigación sobre la convivialidad durante la crisis epidémica mundial de la enfermedad de la covid-19 provocada por el virus SARS COV 2. A partir de un enfoque cualitativo y microscópico basado en un trabajo de campo etnográfico en barrios populares de la ciudad de La Plata, Argentina, durante los años 2020 y 2021, propongo un doble movimiento. Por un lado, utilizar la perspectiva de la convivialidad para explorar la pandemia como experiencia espacial y temporalmente situada, y, en simultáneo, aprovechar esos trazos elaborados por mis anfitriones acerca de su experiencia pandémica para interrogar empírica y analíticamente el concepto de convivialidad abordado en su triple acepción: como formas sociales de procesar la vida juntos, como interacciones específicas entre entidades humanas y no humanas, y como repertorio de saberes acerca de la vida en común.
MODA GİYİM SEKTÖRÜNDE SÜRDÜRÜLEBİLİRLİK ARAYIŞLARI; YAVAŞ MODA’NIN YÜKSELİŞİ
Authors: ONAY İdris , ARSLAN İsmet Kahraman
Published: April 2023

Artan çevresel kaygılar çerçevesinde, hızlı moda iş modeline alternatif olarak yavaş moda, moda endüstrisinde sürdürülebilirliği artırmanın bir yolu olarak ortaya çıkmıştır. Ancak yavaş modanın sürdürülebilir bir kâr marjı üretip üretemeyeceği hala büyük ölçüde bilinmemektedir. Amaç : Bu çalışmanın amacı, tüketicilerin yavaş moda ürünlerini satın alma arzusuna ve bu ürünler için gerekirse daha fazla fiyat ödeme niyetlerine etki eden unsurları incelemektir. Yöntem: Bu çalışma ile algılanan müşteri değeri yaratmaya katkıda bulunan yavaş moda özelliklerini belirleyen ve daha sonra tüketicinin yavaş moda ürünleri satın alma arzusunu ve bu ürünler için daha fazla fiyat ödeme niyetlerini artıran yapısal bir model test etmiştir. Bulgular: 282 Türk tüketicisi verileri üzerinde yapılan analizler, Özgün ürün değeri sunmanın yavaş moda için algılanan müşteri değeri yaratmada önemli ölçüde kritik olduğunu ve algılanan değerin tüketicilerin satın alma arzularını olumlu etkilediğini ortaya koymaktadır. Yapılan diğer analizler, farklı yavaş moda özelliklerinin müşteri değerini belirgin şekilde etkilediğini de ortaya çıkarmaktadır. Bu sonuçlar, yavaş moda şirketlerinin ekonomik olarak sürdürülebilir bir iş modelini güvence altına almak için odaklanabilecekleri potansiyel stratejileri belirlemesinde yardımcı olabilir. Özgünlük: Literatür incelediğinde, Yavaş Moda iş modelinin Türkiye genelinde ekonomik olarak sürdürülebilir bir kar üretip üretemeyeceğine yönelik yapılan çalışmaların sınırlı olduğu görülmüştür. Anılan bu durumun araştırmayı farklı kılan özellik olduğu düşünülmektedir.
Třikrát o mnohočetné paměti
Authors: Hladík Radim
Published: April 2023

The article affirms that a reasonable number of works have been published recently in Czech language, which should theoretically underpin a wider conception of memory studies. At the same time, these studies should not be subsumed under historiography, and above all, they should not employ solely the concepts of identity and social bonds, but also of power and conflict.
Gerbertův úvod do geocentrické astronomie
Authors: Otisk Marek
Published: April 2023

This paper deals with four astronomical tools made and used by Gerbert of Aurillac, archbishop of Rheims and Ravenna, abbot of Bobbio and in 999–1003 pope (under the name Sylvester II.). Gerbert taught quadrivium mainly in Rheims and from his pupil Richer of Rheims (chronicle Historiarum libri quatuor) and from Gerbert’s letters (addresed to his friend and pupil Constantine of Fleury) we know four of his tools, which offered simple and illustrative introduction to the geocentric system of the world: 1. the globe of the world sphere with an adjustable horizon; 2. the observational hemisphere with five parallel circles of world sphere (two polar circles, two tropics and equator); 3. the planetary sphere with zodiac and orbits of planets on the inside and 4. the armillary sphere with stars and constellations on the outside.
Darwinismus a portmannismus: střetnutí nesouměřitelných biologických paradigmat?
Authors: Jaroš Filip
Published: April 2023

The article focuses on the possibility of the cultivation of biology inspired by the work of biologist A. Portmann. Insight into the problem is to some extent limited to the Czech language area, where Portmann’s ideas are relatively well established. The paper analyses the causes of latent tension between so-called Darwinists and Portmannists. There are a lot of misunderstandings at this point. First of all, it must be considered that Portmann didn’t disregard Darwin’s theory. The aim of the article is to show that Portmann’s ideas transcend a traditional Darwinian reduction of a life form to adaptive function. Divergence of these schools of thought comes from different opinions on the nature of science. The paper shows how dissimilarities of aims and means of biological exploration lead to different conclusions about living creatures. For research growing out of Portmann’s ideas, it is necessary not to consider Darwinism as a competitor, but as a thought-provoking partner for a dialogue.
Diskuse o evoluci mezi neo-lamarckismem a neo-darwinismem v českých zemích (1900–1915)
Authors: Hermann Tomáš , Šimůnek Michal
Published: April 2023

The present study focuses on the impact which the vast, fundamental changes in biology of the late 19th and early 20th century had in the Czech Lands. Until the WWI, there existed several distinct and often mutually contradictory theories of evolution of organisms. In the Czech Lands, this multitude of theoretical explanations was complemented by a multi-layered cultural and scientific environment, where Czech and German biology influenced each other and met at various autonomous institutions. One should also keep in mind the differences between Prague and Brno, each a local centre with its scientific traditions and independent links to both Vienna and other European universities. The main subject of this paper are the theoretical biologists who had long-term impact on Czech biological thought or influenced it directly by working here. In about 1900-1915, we witness the first clear and recognised peak in the Czech reception of evolutionism.
Heideggerovo pojetí fakticity řeči jako původu klamu
Authors: Holeček Tomáš
Published: April 2023

The article presents Martin Heidegger’s early conception of foundational questions of logic and science. It focuses on their treatment in the Introduction to Phenomenological Research (the lectures from 1923/1924, published as Gesamtausgabe, Bd. 17). Presenting the conception of phenomenon, perception, language/speech, noun and verb, proposition and deceit, the article shows the fundamental idea of facticity of speaking as the ground of these questions. It uses ideas of existence, fact and time to a-chieve the result. The impact on the most famous early book by Martin Heidegger is also considered.
Říká logicismus něco, co se říkat nemá?
Authors: Kolman Vojtěch
Published: April 2023

The objective of this paper is to analyze the broader significance of Frege’s logicist project against the background of Wittgenstein’s philosophy from both Tractatus and Philosophical Investigations. The article draws on two basic observations, namely (1) that  Frege’s project aims at saying something that was only implicit in everyday arithmetical practice, as the so-called recursion theorem demonstrates, and (2) that the explicitness involved in logicism does not concern the arithmetical operations themselves, but rather the way they are defined. It thus represents the attempt to make explicit not the (arithmetical) rules alone, but rather the rules governing their following, i.e. rules of second-order type. I elaborate on these remarks with short references to Brandom’s refinement of Frege’s expressivist and Wittgenstein’s pragmatist project.
Heideggerův výklad experimentálního charakteru novověké vědy
Authors: Novák Aleš
Published: April 2023

While showing the mathéma-character of modern science, Martin Heidegger (1889-1976) sharpens his analysis of its essence by interpreting the key part of its method, which he claims to consist of the “hypothesis-experiment complex”. In Heidegger’s interpretation, the experimental feature of modern science means the former metaphysical act of logical prescription for the general understanding of the meaning of “being”. Thus, Heidegger analyses the fourfold concept of “experience”, which distinguishes the modern science from all the older conceptions of “science”. Nevertheless, all what Heidegger ultimately tries to achieve, is to gain a clear insight into the essence of the temporal character of “being”.
O problémech a cílech řízení znalostí
Authors: Tondl Ladislav
Published: April 2023

The contribution presents a brief outline of possible approaches to the concept "knowledge". The main emphasis is given on the relevance of the selected and applied knowledge with regards to the given task or problem-solving situation and to the competence of the subjects of knowledge, especially concerning the selection and integration of knowledge. It includes not only the integration of various spheres of knowledge, but also the integration of knowledge and values.
Humova skepse v Masarykově pojednání o počtu pravděpodobnosti a dalších pracích
Authors: Novotný Zdeněk
Published: April 2023

It was Hume's concept of knowledge that marked Masaryk's philosophy more than influential Kant. Masaryk devoted Hume his inaugural lecture The Probability Calculus and Hume's Scepticism at Prague University in 1882. He tried to face his scepticism concerning causation and induction by a formula P = n:(n+1) or P = (n+1):(n+2) where P means the increasing probability that an event that had happened n times in the past will happen again. Hume stresses that there is an essential difference between probability and certainty, and we have no logical reason to presuppose that the past experience (however massive) is legitimate for expectation that the future will resemble to the past. Only our belief, not knowledge, leads us to that. Although Masaryk did not accept Hume's scepticism, he had deep understanding for his way of thinking. Reflection of Hume's influence on Masaryk in Czech philosophy is unsatisfactory, which is stated in this article.
„Faciamus experimentum in corpore vili“: od kritické analýzy lékařského výzkumu ke konceptu argumentační koprodukce
Authors: Durnová Anna
Published: April 2023

The book by Grgoire Chamayou, Les corps vils: Exprimenter sur les tres humains aux 18e et 19e sicles studies practices of medical research in 18th and 19th centuries. Along various stories of ignoble bodies", as he qualifies human beings that had been subjected to medical research of that time, the author shows that practicing medical research is intrinsically linked to historical and social circumstances. With this thesis, the book responds to the recent critical approaches to medical research that have emphasized that science interacts with society and vice versa. The article summarizes the existing debate in STS, medical sociology and sociology of scientific knowledge in order to present a concept of "argumentative coproduction" which enables to capture the dynamics between science and society, especially the mechanisms that medical research produces to govern societies.
David Hume a věda o člověku
Authors: Parusniková Zuzana
Published: April 2023

Hume built his philosophical system with the ambition to become a Newton of human nature. His science of man is the fulfillment of this project. Hume was inspired by the Newtonian experimental empirical method excluding hypotheses, and he applied this method to moral sciences; he took those to be the basis of all other knowledge. The observation of human cognitive faculties, however, brought him to sceptical conclusions concerning the rational justification of empirical sciences. His original ambitions are thus undermined and his scepticism leads to the loss of legitimacy of natural science. The core of Hume's science of man is twofold - it consists in the analysis of mind and of human social behaviour. Hume contributed to the development of psychology and helped to form social sciences as a specific research area. Following his empirical method based on observation, his science of man has rather a documentary role than any normative features.
O dialektice ve vědě a sociologii
Authors: Petrusek Miloslav
Published: April 2023

After the break-up of totalitarian regimes grounded in Marxist ideology, social science tended to avoid the concept of dialectics, or directly excluded it from its scientific agenda. This article tries to elaborate on three questions (concentrating on less familiar or neglected conceptions, e. g. the approaches worked out by Gurvitch, Kojève, Sartre, Stalin, etc.) relating to the development and transformations of dialectic in various sociological conceptions: a) is "dialectical sociology" possible, b) is the concept of "dialectics" redundant (radical and critical sociologies are also "dialectical", c) what are the elementary principles which could or should guide "dialectical studies" of social reality. At the end, the difference between principles of the so-called Lazarsfeldian and radically critical paradigm is demonstrated against the background of empirical research.
Historiografická metoda Thomase Kuhna a její význam z hlediska sociologie vědeckého poznání
Authors: Benda Libor
Published: April 2023

Thomas Kuhn's importance for further development of thinking about science and, in particular, for the rise of the sociology of scientific knowledge is usually associated with his The Structure of Scientific Revolutions, whereas his preceding historical works are seldom reflected in this regard. This paper analyzes the latter and attempts to describe the methodology of Kuhn's approach to the history of science applied in them. By comparing it with the tenets of the early sociology of scientific knowledge (Barry Barnes, David Bloor), the paper attempts to find out to what extent should Kuhn's historical works be recognized as influential from the perspective of sociological approach. Since these works originated at the time when historiography of science was under strong influence of Alexandre Koyré, the paper also examines the methodology of his works and evaluates how much Kuhn's approach surpasses standard post-war historiography of science in the vein of Koyré's tradition.
Humova teorie kausality: existuje více než jedna?
Authors: Hill James
Published: April 2023

It is traditionally assumed that there is only one theory of causality in Hume's writings. In this article it is shown that we can distinguish between an early and mature theory. It is argued that the mature theory, strongly influenced by Newton's physics, accords with the New Hume (sceptical realist) interpretation by asserting that real causal relations are not accessible to the human mind.
O samotné myšlence jednotné sociologie: Harvard a Columbia
Authors: Balon Jan
Published: April 2023

On the Very Idea of Unified Sociology: Harvard and ColumbiaAbstract: The article concentrates on the historical context of American sociology's development in the period between 1930 and 1965, which is here associated with a specific project of the  field's unification elaborated at Harvard University and Columbia University. It is argued that the idea of unified sociology is worked in the very project of American sociology as a science and found its genuine expression in the efforts to reach "objectivity and coherence" of sociological thought/knowledge. It also distinctly formed the professional identity of the discipline. It was expected that the scientific integrity would be achieved by means of securing the continuity of theory and practice, which was to provide a general methodological pillar for cumulative research.  The historical contextualization of this formative period studies how the very idea of unified sociology affected both theoretical and methodological perspectives within the discipline and also the possibility of its integrated research agenda.O samotné myšlence jednotné sociologie: Harvard a ColumbiaAbstrakt:  Článek se zaměřuje na historický kontext vývoje americké sociologie v období mezi lety 1930-1965, jež je spojeno se specifickým projektem sjednocení oboru rozpracovaným na Harvardské a Kolumbijské univerzitě. Samotná myšlenka jednotné sociologie je neoddělitelně vpletena do celého projektu americké sociologie jako vědy a své „čisté" vyjádření nalezla v úsilí prokázat „objektivitu a koherenci" sociologického myšlení/vědění. Zcela zřetelně také formovala profesní identitu oboru. Prostředkem zajištění vědecké integrity bylo především zajištění kontinuity teorie a praxe, ježby založilo a o něž by se mohlo opírat pevné metodologické „sebevědomí". Historická kontextualizace tohoto formativního období si klade za cíl sledovat, nakolik myšlenka sjednocené sociologie ovlivnila teoretické a metodologické perspektivy v rámci oboru i vlastní představy o možnosti jeho integrované výzkumné agendy.
RADIATION DIAGNOSIS OF SEROUS CARCIONEOMA OF THE OVARY OF ENORMOUS SIZE IN A PATIENT OF POSTMENOPAUSAL AGE (CLINICAL CASE)
Authors: Diomidova Valentina N. , Safonova Marina A. , Starostina Tatyana V. , Vazanov Andrey A. , Glyakin Dmitry S.
Published: April 2023

Topicality. Among the tumors of the female genital organs, ovarian cancer is considered one of the most common. Due to the lack of a specific clinical picture at an early stage, in more than half of cases there is a delayed detection of ovarian cancer. In view of this, an urgent problem in oncogynecology remains the timely diagnosis of ovarian cancer. The purpose of the work is to demonstrate the complexity and untimely diagnosis of ovarian cancer on the example of the presented clinical case of primary radiation diagnosis of serous ovarian carcinoma of enormous size in a postmenopausal patient. Outcomes. The article reflects some experience of domestic and foreign researchers, where the reasons that explain the late diagnosis of ovarian cancer are studied. A case from clinical practice with an analysis of the development of the clinical picture of the disease, the tactics of patient management is presented. This clinical example is an example of a belated diagnosis of ovarian cancer in a postmenopausal patient. Unfortunately, in this situation, at the time of the initial diagnosis of ovarian cancer, the tumor already had a huge size, probably because of this, the clinical picture of the disease and the objective assessment of the patient's condition were regarded erroneously. Conclusion. The analysis of this clinical example convincingly indicates that only the implementation of a complete algorithm for the complex use of anamnestic, laboratory (including tumor markers), instrumental (primarily radiation diagnostic methods, such as ultrasound, computed tomography) and other diagnostic methods is the basis for the timely diagnosis of ovarian cancer.
BIOLOGICAL ROLE OF THIOREDOXIN-MEDIATED INTRACELLULAR SIGNALING DURING PHYSIOLOGICAL AGING (LITERATURE REVIEW)
Authors: Tasakova Olga S. , Golubtsova Natalya N. , Gunin Andrei G.
Published: April 2023

Thioredoxin is a low molecular weight protein found in all organisms. It is associated with the regulation of numerous cellular processes such as gene expression, antioxidant response, apoptosis, and proliferation. In humans, thioredoxin is represented by two functionally different forms, Trx1 and Trx2. The review contains the results of studies on the biological role of thioredoxin, with special attention paid to its role in the regulation of the physiological aging process. The aim of the study was to study the available literature sources that publish materials on the biological role of thioredoxin, paying special attention to its significance in the regulation of the physiological aging process. Materials and methods. To achieve the goal of the study, methods of analysis, generalization, comparison and systematization of these publications of domestic and foreign authors were used. Results. The main function of the thioredoxin-dependent system is antioxidant activity. Trx and glutathione (GSH) play a central role in counteracting oxidative stress. In addition to its antioxidant properties, Trx, unlike other antioxidant enzymes, plays an important role in maintaining the redox state of cells and in regulating redox signaling. There is a lot of evidence in the literature that shows the stimulating effect of thioredoxin on tissue proliferation. The Trx system is hypothesized to promote the development and spread of cancer through various mechanisms, including inhibition of apoptosis, promotion of cell growth, and maintenance of angiogenesis. There is also evidence of an important role of the thioredoxin system in aging. Conclusions. Thus, there are data on the participation of the thioredoxin system in the processes of aging, carcinogenesis, regulation of proliferation, and apoptosis. However, the role of thioredoxin in age-related changes in organs has not been studied enough, so additional studies are needed.
THE ROLE OF MAST CELLS IN CARCINOGENESIS (LITERATURE REVIEW)
Authors: Timofeeva Natalya Yu. , Bubnova Natalia V. , Samakina Ekaterina S. , Stomenskaya Irina S. , Kostrova Olga Yu. , Struchko Gleb Yu. , Kotelkina Anastasiia A.
Published: April 2023

Mast cells are an important link in the immune system. They are involved in many pathological processes such as stress, inflammation, autoimmune processes and carcinogenesis. The purpose of the review is to summarize the data on the role of mast cells in carcinogenesis. Materials and methods. Review of available literature sources published in Elibrary and PubMed. Results. Tumor growth in the body is accompanied by immune system dysfunction and mast cell response. Mast cells are able to stimulate tumour growth through the secretion of proteases, angiogenic and growth factors, and at the same time have a tumour suppressive effect. The response of the mast cell population depends on the type of tissue from which the tumor is developing, the speed and stage of the process, the localization of the mast cells, and the combination of pro- and anti-tumor factors. During tumour development and growth, total degranulation of mast cells occurs. In addition, mast cells in normal and tumor tissue differ in structure. This article provides information on the role of mast cells in carcinogenesis. Conclusion. Thus, mast cells on the one hand positively affect tumor growth through the synthesis of proteases, growth and angiogenic factors, and on the other hand, act as inhibitors of malignant growth. The response of mastocytes directly depends on the tissue in which tumour develops, on its type and degree of malignancy, the stage of pathological process, localization of mast cells and the degree of their activation, as well as the total balance of pro- and antitumour effects.
CHARACTERISTICS OF THE IMMUNE STATUS IN PATIENTS WITH DECOMPENSATION OF LIVER CIRRHOSIS
Authors: Ivanova Antonina L. , Karzakova Luiza M. , Odintsova Anastasia V. , Kudryashov Sergei I. , Bagildinskaya Marina V. , Zhuravleva Nadezhda V.
Published: April 2023

Liver cirrhosis continues to be an acute problem of modern medicine due to the high rates of its prevalence and mortality. The high mortality rate is caused by the development of the number of life–threatening complications in decompensated forms of liver cirrhosis – hepatorenal syndrome, infections and varicose bleeding. Hepatorenal syndrome and infections are the result of immunological shifts occurring during decompensation of liver cirrhosis. Currently available literature data do not allow us to create a complete picture of the functional state of various links of adaptive immunity with decompensated liver cirrhosis. The aim of the research was to study the characteristic features of adaptive immunity in patients with decompensated liver cirrhosis. Material and methods. The prospective cohort study included 136 patients with decompensated liver cirrhosis, who received inpatient treatment in the hepatological department of the multidisciplinary hospital. The cohort of examined patients was divided into two groups, one of which included patients with liver cirrhosis of viral origin (n = 78), the other – patients with alcoholic liver cirrhosis (n = 58). In addition to the generally accepted standard methods, the patient examination program included immunological tests: identification of T- and B-lymphocytes, immunoregulatory and activated subpopulations of T-lymphocytes by the method of immunophenotyping peripheral blood mononuclear cells using monoclonal antibodies. The serum levels of immunoglobulins IgM, IgG, IgA, circulating immune complexes were determined by immunoturbidimetric method. Results. The study of indicators of the humoral link of adaptive immunity revealed an increase in the number of B cells, an increase in IgM, IgG, IgA and circulating immune complexes in patients with decompensated liver cirrhosis. The cellular link of adaptive immunity was characterized by an increase in the relative content of T helper cells, activated T cells against the background of a decrease in the number of immature T cells and T regulatory cells. Conclusions. The distinctive features of adaptive immunity in patients with decompensated liver cirrhosis are simultaneous activation of both humoral and cellular components, which, apparently, supports the systemic inflammatory process and the associated progressive liver fibrosis.
Sistem Informasi Simpan Pinjam Dan Pengelolaan Hasil Pertanian Bumdes Baru Kabupaten Barito Selatan Berbasis Website
Authors: Sari Nova Noor Kamala , Olpah Syahrida
Published: April 2023

BUMDes Baru is a village-owned enterprise established with the intention to improve the welfare of the people of Desa Baru through its main program, namely savings and loans, as well as additional programs in the form of management of agricultural products and village markets. Currently, all activities including savings and loans transactions, PKR levies, facility rentals and making monthly reports for BUMDes are still carried out manually. This resulted in people having to come to the BUMDes secretariat repeatedly in order to take care of loan applications. Therefore, a Website-Based Information System for Savings and Loans and Management of Agricultural Products of New Village-Owned Enterprises (BUMDes) of South Barito Regency was created..

The methodology used in the Savings and Loans Information System and Agricultural Product Management of the New BUMDes is waterfall, with stages, namely the Requirements Definition stage which is carried out in making business process designs and flowcharts, System and Software Design is carried out in making Data Flow Diagrams, Entity Relationship Diagrams, Databases and Interface Design, Implementation and Unit Testing with the programming languages ​​used, namely PHP, Javascript, PhpMyAdmin and Integration and System Testing using the Blackbox Testing method.

This website is intended to facilitate the public in seeking information about the New BUMDes, facilitating members in conducting savings and loan transactions, leasing facilities and kiosks, PKR retribution transactions, and facilitating the management of BUMDes to be more organized and detailed.
Rancang Bangun Sistem Informasi Akademik Smpn 1 Kahayan Hilir Berbasis Web
Authors: Sylviana Felicia , Lorendi Nataniel
Published: April 2023

SMPN 1 Kahayan Hilir is one of the junior high schools in Pulang Pisau. Every year the number of students at SMPN 1 Kahayan Hilir continues to increase, so student data is difficult to maintain. SMPN 1 Kahayan Hilir, still uses the manual method in data recap. Starting from the management of student data, teacher and academic data stored in hard copies or sheets of paper for data recap. Where it fills the storage space of the office and if something happens like a fire, the data will be lost. Backup data is also still using a flash, where the flash can not guarantee data security. Moreover, the size of the flash is not necessarily sufficient for all the data. So from these problems, an application was made for web-based data management on the Academic Information system of SMPN 1 Kahayan Hilir. The academic information system uses the waterfall software development method, which consists of the stages of analysis, design, implementation, testing and maintenance. At the analysis and design stage using DFD and ERD for data design. While at the testing stage the method used is the black box method. The results obtained in the study are in the form of a website with features for managing student data, identity, class, class schedule, class, attendance, grades, curriculum, subject groups, academic year and teachers who are integrated with each other. The results of the black box test have been obtained with evidence of testing the black box sheet by the teacher of SMPN 1 Kahayan Hilir.
HEMŞİRELERİN COVID-19 TANILI HASTALAR İLE ÇALIŞMAYA İLİŞKİN GÖRÜŞLERİ VE YAŞADIKLARI ZORLUKLAR
Authors: SARI Canan , ADIGÜZEL Leyla , DEMİRBAĞ Birsel Canan
Published: April 2023

Amaç: Bu calışmada, hemşirelerin pandemi sürecinde COVID-19 tanılı hastalar

ile çalışmaya ilişkin görüşleri ve yaşadıkları zorlukların belirlenmesi amaçlanmıştır.

Yöntem: Tanımlayıcı ve kesitsel tipte planlanan çalışma, 05 Mart-10 Haziran

2022 tarihleri arasında çalışmaya katılmaya gönüllü 188 hemşire ile yürütüldü. Çalışmanın verileri Sosyodemografik Özellikler ve Mesleğe İlişkin Faktörler Veri Formu kullanılarak toplandı. Veriler sayı (n), yüzde (%), ortalama ve standart sapma

ve ki kare testi kullanılarak analiz edildi.

Bulgular: Hemşirelerin %81.9’u kadın, %69.1’i önlisans/lisans mezunudur.

Hemşirelerin %88.3’ünün pandemi sürecinde aile ve sosyal yaşam düzeninin değiştiğini ve %67.6’sı sosyal yaşamını kısıtlamak zorunda kaldığını ifade etti. Katılımcılar pandemi sürecinde hemşirelerin %60.1’i hasta sayısı, %55.3’ü mesai

saatleri ve %89.9’u iş yükünün arttığını ifade etti. Hemşirelerin %28.7’si hasta/yakınları tarafından sözlü şiddete maruz kaldığı belirlendi. Hemşirelerin %47.9’unun

COVID-19 hastalarının tedavi gördüğü birimlerde, %57.8’inin gönülsüz olarak ve

%79.3’ünün oryantasyon eğitimi almadan çalıştığı saptandı. Hemşirelerin %57.4’ü

haftada 40 saat yerine 20 saat çalışılması, %54.8’i daha fazla ücret ödenmesi durumunda COVID pozitif hastalarda daha istekli çalışacaklarını ifade etti. Hemşirelerin %66’sının pandemi sürecinde maske takmayan ve sosyal mesafe kurallarına

uymayan kişileri gördüğünde sağlık personeli olarak boşuna uğraştığını düşündüğünü belirlendi. COVID pozitif hastalarla çalışan hemşirelerin hasta/yakınları

tarafından daha yüksek oranda sözlü şiddete maruz kaldığı belirlendi (p
Formação de professores para a promoção da saúde no Ensino Básico por meio de manual didático
Authors: Brito Antonia Janieiry Ribeiro da Silva , Nascimento Karla Angélica Silva do
Published: April 2023

O estudo tem como objetivo analisar as contribuições de um manual didático acerca das ações de prevenção e cuidado com a saúde na formação inicial de professores. A pesquisa foi conduzida em três fases: i) levantamento: aplicação do questionário online com os alunos do curso de Pedagogia e elaboração do manual; ii) implementação do manual mediante minicurso híbrido; iii) descrição, organização dos dados e análise sobre a validação do manual pelos acadêmicos de Pedagogia. O conhecimento dos participantes acerca da saúde na escola era mínimo antes de conhecerem o manual e vivenciarem as atividades no minicurso. Após o minicurso, os alunos reconheceram a importância do estudo sobre saúde – higiene corporal, bucal, mental e práticas corporais. Apesar disso, a maioria pensava que o tema saúde deveria ser tratado somente por especialistas, mas entendeu que os professores e as escolas desempenham um papel importante na promoção da saúde. Os resultados revelam que o manual utilizado ampliou o conhecimento e as habilidades dos alunos a respeito da saúde para sua promoção na escola. Portanto, a preocupação com o tema saúde deve superar a forma reducionista como é vista e ser incorporada no currículo dos estudantes de graduação para que, dessa forma, o tema Saúde na Educação possa ser desenvolvido de forma clara e com propriedade.
Researching Entrepreneurial Beliefs in Career Decision-making
Authors: Tampouri Sofia , Kaliris Andronikos , Kakouris Alexandros
Published: April 2023

Abstract

Entrepreneurship is suggested as a key-mechanism for endogenous growth and social cohesion in modern, knowledge-driven societies and economies. Whether the youth will develop entrepreneurial competencies and initiatives has been considered crucial for economic growth and development and a key-subject of education and career counseling. Despite an increasing body of theoretical and empirical literature which mainly emphasize the formation of entrepreneurial intention and the strengthening of entrepreneurial self-efficacy -usually as a result of some intervention-, the findings show deficiencies or relative ambiguity, in terms of explaining the complex factors (e.g. entrepreneurial mindset, dysfunctional beliefs) associated with entrepreneurial intention and behavior. The present conceptual paper presents a synthetic literature review aiming at a deeper understanding of entrepreneurial intention and behavior. Based on the emergence of new, more explanatory, models to predict entrepreneurial behavior we emphasize how relevant research could approach this topic through the lens of the Socio-Cognitive Career Theory - driven by self-efficacy, outcome expectations and goal-directed activity - given that to date few studies have used this theoretical framework. We also suggest that the traditional entrepreneurial self-efficacy concept is investigated along with a new framework (ASKO) to measure beliefs regarding success of new ventures. ASKO typology traces a variety of different entrepreneurial mindsets within the person-environment dichotomy. Moreover, the potential contribution of dysfunctional career beliefs and locus of control in the formation of entrepreneurial behavior is examined. Career decision process and entrepreneurial career choices are highly complex and entail elements of various theoretical perspectives. The present literature review sheds light to our understanding of entrepreneurial career choices and suggests holistic in-depth research that will provide rich explanatory information on a wide range of behaviors. Finally, the present review provides opportunities to get insights regarding the nature and potential influence of support interventions in the context of entrepreneurship education and career counseling.

Keywords: Entrepreneurship, career beliefs, entrepreneurial self-efficacy, ASKO typology, career counseling, entrepreneurship education.
Encompassing Embodiment in Entrepreneurial Learning
Authors: Voudda Aikaterini-Panagiota , Kakouris Alexandros
Published: April 2023

Abstract

The present conceptual article discusses non-cognitive aspects of entrepreneurial learning. Entrepreneurs are known to undergo extreme experience phases during establishing their firms where peak experience, peak performance and flow counteract. As a result, increasing anxiety and stress may hamper their performance. Non-cognitive skills that consider simultaneously mental processes, emotions and spirit in connection with the human neurophysiological system in a holistic, human learning process, could appear more efficient in describing how entrepreneurial learning occurs in stressful situations. In the present discussion somatic learning education is suggested as a possibility to enhance entrepreneurial learning, creativity and performance in stressful situations. As non-cognitive entrepreneurial skills have been overlooked in the extant literature, the present discussion initiates a discussion for further research in the field. The concepts of holistic entrepreneurial learning, embodiment and somatic learning are described while their relevance to stressful business start-upping and entrepreneurial well-being is sought. The article concludes with relevant research questions for further examination.

Keywords: Entrepreneurial education, Embodiment, Somatics, Peak performance, Peak experience, Flow, Well-being, Stress regulation, Innovation, Creativity.