bluuebunny/crossref_metadata_2025 huggingface dataset:
Reliability of Point M as landmark for analysis of sagittal relation of maxilla
Authors: Bharti Anu , Ray Saugat , Datana Sanjeev , Thapa Amrit
Published: December 2023

Most of the several cephalometric analyses used for the diagnosis of sagittal dysplasia, Point A is the most widely used indicator for ascertaining of maxillary position. By the virtue of difficulty in locating point A in many cases, alternative methods had been proposed for precise location of point A but there are only few studies on the reliability of these alternative points. Point M is one such indicator for evaluating the sagittal position of maxilla. The objective of this study is to measure and compare the reliability of point A and point M.

Lateral cephalogram of 50 subjects (11-20 years) were included in the study consisting of all types of skeletal malocclusions. Point A and point M were identified by two different group of orthodontists. Linear and angular measurements through both the points were analysed and compared between the observers using interclass correlation.

Interclass correlation coefficient of linear and angular parameters of point M was found to be higher than point A.

Point M may be considered as more reliable alternative for point A in two dimensional cephalometric analysis.
Investigation of the edge effect in composites using the ANSYS software in a two-dimensional formulation
Authors: Skvortsov Yu. V. , Evtushenko M. A.
Published: December 2023

The possibility of using the universal software ANSYS to study the concentration of interlaminar stresses near the free edges of laminated composites in a two-dimensional finite element formulation is considered. In this case, the cross-section of a rectangular four-layer composite plate of finite width with free side edges subject to uniform axial deformation is simulated. To create it, an original technique is proposed which consists in using thermal stress. The presented calculation results are in good agreement with the results of other authors.
Features of the use of directional fixed antennas of a high-speed radio link on a small spacecraft AIST-2T
Authors: Eremina V. V. , Erkov I. O. , Zhuravlev A. A. , Maslov I. V. , Pyrinov N. I.
Published: December 2023

The correct installation of antenna-feeder devices on board a small spacecraft and the choice of their parameters make it possible to ensure the solution of target problems with high quality. The main problematic issues of placement of antenna-feeder devices of the on-board equipment of the radio link for the transmission of target information on the SSC “AIST-2T” and the adopted design solutions are considered.
Method of automated arrangement of devices in a spacecraft compartment taking into account connection to interface connectors of feed-through plates of an on-board cable system
Authors: Belyakov A. A. , Prihodko V. I. , Shulepov A. I.
Published: December 2023

The article proposes a method for automated arrangement of on-board equipment in the spacecraft compartment, connected to external devices through sealed adapters by the on-board cable system routes. The purpose is to create a program that allows automated placing of a part of the on-board equipment in the compartment, taking into account the existing practical principles for developing instrument placement schemes, one of which is to minimize the mass of the on-board cable system. The mathematical model is described using the matrix-topological layout method in a procedural form, as well as in a numerical form for calculating the coordinates of the placement of devices and estimating the number of cycles to find the final solution. Recommendations are provided to ensure that the full range of technical requirements is taken into account in the future. An outline flowchart of the method algorithm is presented with support in the high-level Python programming language. The software implementation of the method was carried out with emulators. Testing was carried drawing on the example of a compartment of one of the advanced space vehicles. The effectiveness of the method is evaluated by comparing the number of cycles needed to obtain the result and the total time spent on the layout relative to the control data known from the job statistics.
Methodology of delivering space parts, tools and accessories to a near Earth orbital station on the basis of the reliability factor
Authors: Zheleznov I. V. , Uperchuk R. A. , Eroshenko V. K.
Published: December 2023

The main aspects of the deployment of multi-module orbital manned stations are considered. The methodology for planning the delivery of spare parts, tools and accessories used in planning of transport operations to the International Space Station, is analyzed. It is shown that its application is related to the problem of mathematical programming with a large number of variables, which complicates the process of finding the optimal planning option in terms of economic efficiency. Transport operations to national manned orbital stations are carried out less frequently as compared to the International Space Station due to the enormous costs of spacecraft launches taking into account possible emergency situations. An approach to improving the methodology for planning the delivery of spare parts, tools and accessories for possible use on national manned orbital stations is proposed. It consists in taking into account the reliability of on-board equipment. The advantage of the improved methodology is simplification of planning transport operations without the use of mathematical programming. In addition, the improved methodology is clear, simple and can be implemented step by step.
O fakcie wiary
Authors: Gębura Błażej
Published: December 2023

Jacek Wojtysiak twierdzi, że powołując się na zachodzenie wielkiego faktu wiary, można wykazać przewagę teizmu nad ateizmem. Wobec tego poglądu formułuję trzy zarzuty: zarzut z rocznika statystycznego, zarzut z najmniejszego faktu wiary oraz zarzut z niempirycznych racji. Zarzut z rocznika statystycznego zwraca uwagę na fakt, że wielkość faktu wiary jest zawsze zrelatywizowana do momentu w czasie, w którym jest on stwierdzany. A to rodzi pytanie, na który fakt powinien powołać się teista. Zarzut z niewielkiego faktu wiary sugeruje, że w sporze między teizmem a ateizmem nie ma znaczenia, czy fakt wiary podlega pluralizacji, a więc jak wielu podmiotów dotyczy. Zarzut z nieempirycznych racji promuje pogląd, w myśl którego ustalenie empirycznych okoliczności funkcjonowania określonych religii nie zbliża teisty i ateisty do rozstrzygnięcia prowadzonego przez nich sporu.
Biodiesel production from microalgae: a technical- financial analysis
Authors: Oliveira Lima Luana , DE PRA CARVALHO ANDRIELE , ZUBER ANDRÉ , HENRIQUE REKTENVALD JONAS
Published: December 2023

Aiming to elucidate the costs contained in the production chain of biodiesel through microalgae, this work sought to gather several variables present in the composition of a biodiesel production industry from microalgae, entering a conjuncture of hypotheses, for the realization of mass and energy balances, as well as for the elaboration of financial analysis. Mass balances were performed, considering conversion rates, yield, reaction stoichiometry, density of compounds, among others. In the end, after all calculations, an annual production of 22.872,78 m3 of biodiesel was obtained. In the energy balance phase, the equipment containing temperature changes was taken into account to define the energy expenditure of the industry, making it possible to then account for the necessary steam consumption, which was calculated as 2.765,54 kg h-1. Afterward the monetary values necessary for the company´s operation were estimated, accounting for fixed and variable costs, with subsequent evaluation of indicators, such as the discounted payback, the internal rate of return, the net present value and the break-even point, which indicate the feasibility of the project under the conditions indicated during the work.
 Na fase de balanço de energia, levou-se em consideração os equipamentos que continham alteração de temperatura, para definição do gasto energético da indústria, sendo possível então contabilizar o consumo de vapor necessário, o qual, foi calculado em 2.765,54 kg h-1.
 Após foram estimados os valores monetários necessários ao funcionamento da empresa, contabilizando-se custos fixos e variáveis, com conseguinte avaliação de indicadores financeiros, como o payback descontado, a taxa interna de retorno, o valor presente líquido e o ponto de equilíbrio, os quais, indicam a viabilidade do projeto nas condições indicadas durante o trabalho. O payback descontado retornou, nas condições propostas, o tempo de 4,15 anos para recuperação do investimento e o ponto de equilíbrio evidenciou a necessidade de produção de 5437,46 m3 de biodiesel para que a empresa passe a ter lucro.
Palavras-chave:  biodiesel; microalgas; balanço de massa; balanço de energia; payback; ponto de equilíbrio.
MATA ATLÂNTICA E RESERVAS DA BIOSFERA: entrevista com José Pedro de Oliveira Costa
Authors: Bezerra Bianca Cristina Costa , Gonçalves Hélio Inagake Toth , Paixão Ravel
Published: December 2023

José Pedro de Oliveira Costa nasceu em Taubaté, São Paulo. É graduado em Arquitetura e Urbanismo pela Universidade Mackenzie, mestre em Planejamento Ambiental pela Universidade da Califórnia e doutor em Estruturas Ambientais pela Universidade de São Paulo, onde atuou como professor por mais de quarenta anos. Hoje, atua como pesquisador doInstituto de Estudos Avançados da Universidade de São Paulo. Foi o primeiro secretário do Meio Ambiente do Estado de São Paulo e por duas vezes secretário nacional de Biodiversidade e Florestas do Ministério do Meio Ambiente, tendo sido o responsável pela criação de expressivas áreas protegidas no Brasil. É autor de Desenhos Musicados (Massao Ohno), Circumscapes & Promenades (UC Berkeley), Aiuruoca (EDUSP) e Uma História das Florestas Brasileiras (Autêntica) entre outros livros e artigos.
„Gamebook” wzbogacony literacką przeszłością – analiza gry paragrafowej „Dziady część V. Dziady, które nie spieprzają” autorstwa Mikołaja Kołyszki
Authors: Sowa Julia
Published: December 2023

Artykuł porusza zagadnienia ukazujące powiązania postmodernistycznych kategorii pastiszu i parodii w odniesieniu do gier paragrafowych. Pierwsza część tekstu stanowi przekrój najważniejszych kwestii teoretycznych dla późniejszej analizy paragrafówki, zaczynając od przedstawienia jej definicji, najpopularniejszych gatunków, a także podstawowego podziału gier. W związku z problematyką gamebooków zwracam również uwagę na zwiększającą się intermedialność współczesnych utworów, a także znaczenie drugoosobowej narracji. Wspominam również o gatunku gier artystycznych (art games) oraz krótko przytaczam twórczość jednej z ich przedstawicielek – Anny Anthropy. Następnie omawiam postmodernistyczne kategorie pastiszu i parodii wraz z ich znaczeniem w zestawieniu z relacją przeszłość-teraźniejszość. W kontekście parodii wspominam również o podziale Gérarda Genette’a na transtekstualne odniesienia między utworami. Wszystkie wymienione zagadnienia znajdą odniesienie podczas analizy gry paragrafowej stanowiącej „półoficjalną” kontynuację Mickiewiczowskich Dziadów łączących parodystycznie ujętą kulturę ludową ze współczesnymi elementami nowych mediów.
Respuesta agronómica de un híbrido de maíz (Zea mays L.) a diferentes densidades de siembra
Authors: Salazar Carranza Luis Fernando , Véliz Zamora Diana Verónica , Mestanza Uquillas Camilo Alexander , Villacís Seme Jennifer Yamali
Published: December 2023

El trabajo investigativo se desarrolló en las inmediaciones de la finca “La Victoria”, localizada en el km 32 vía al cantón Ventanas, provincia de Los Ríos y consistió en evaluar lotes experimentales de maíz, empleando un híbrido simple (Centella) a distintos distanciamientos de siembra. Se evaluaron tres tratamientos en estudio: T1 (60 x 20cm), T2 (70 x 20 cm) y T3 (80 x 20 cm), dispuestos en un DCA con cinco repeticiones. Las variables evaluadas fueron: altura de planta (cm), diámetro del tallo (cm), número de hilera de mazorcas, longitud de la mazorca (cm), diámetro de la mazorca (cm), peso de 100 semillas (g), rendimiento del grano (kg/ha), fenología y análisis económico. En cuanto a altura de planta, diámetro de tallo y numero de hileras de mazorcas, no se mostraron diferencias significativas entre tratamientos, mientras en las variables longitud y diámetro de la mazorca, peso de 100 semillas, rendimiento de grano y en los ingresos netos del análisis económico, destacó T1 por sobre los demás tratamientos. No obstante, en esta última variable, es importante destacar que T2 mostró una mejor relación beneficio/costo, llegando a registrar mayores ganancias por cada dólar de inversión. Finalmente, en cuanto a la fenología se lograron identificar seis de las etapas más relevantes estas son: VE, V2, Vn, Vt, R1 y R4.
Моделирование отклика кремниевого фотоумножителя серии EQR-15 в фреймворке Allpix
Authors: Флусова Дарья Сергеевна , Бикметов Никита Рафаэльевич , Гоголев Алексей Сергеевич
Published: December 2023

Рассматривается процесс моделирования отклика кремниевого фотоумножителя EQR-15 11-6060D-S, используемого в прототипе гиперспектрального счетчика рентгеновского излучения. Доработанный прототип предполагается к установке в дифрактометре высокого разрешения на станции 1-2 ЦКП СКИФ. Один канал детектора представляет собой кристалл сцинтиллятора LaBr3, оптически связанный с ним фотоумножитель, схему считывания и оцифровки сигнала. Модель была создана с помощью свободного программного обеспечения и представляет собой взаимосвязанные модели сцинтиллятора, матрицы фотоумножителя и системы оцифровки сигнала. Представлены первые результаты моделирования и их согласие с экспериментом. Разработанная цифровая модель позволит проводить предварительные исследования при проектировке детекторов ионизирующего излучения с использованием различных кремниевых фотоумножителей и кристаллов сцинтиллятора.
Integración tecnológica e innovación educativa en carreras STEAM: análisis multidimensional de un caso
Authors: Rodríguez Guillermo Luján , Andrés Gonzalo Darío , Gallucci Pablo Guillermo , Sklate María Florencia , Esquivel Isidro
Published: December 2023

El presente trabajo reflexiona en torno a la adaptación de un modelo comunicacional aplicado en el análisis de experiencias de aprendizaje que vincularon la construcción de conocimiento con el uso de tecnologías digitales. Particularmente se analiza un caso de estudio referido a una actividad realizada en el marco de una carrera del área de las Ciencias, Tecnologías, Ingeniería y Matemáticas, y que a su vez incluyó criterios vinculados al Arte (STEAM). Los estudiantes debieron diseñar y construir en grupo un juguete, integrando de manera explícita conceptos vinculados a las áreas citadas y concretando la materialidad del mismo. Para la observación se tomó como punto de partida las cuatro dimensiones conceptuales del modelo: Institucional, Social, Tecnológico e Intermedial, realizando los ajustes necesarios. Las primeras conclusiones dan cuenta de la riqueza analítica del modelo y los aportes propositivos en torno a repensar experiencias de características similares. Se concluye que el desarrollo de Prácticas Educativas Mediatizadas, con una propuesta pedagógica que incluya la participación-acción de docentes y estudiantes, fortalece la perspectiva transdisciplinar en las carreras STEAM, posibilitando que no sólo se contribuya al aprendizaje de tecnologías digitales, sino que también se impulse la innovación tecnológica, bajo la modalidad de FabLab físico-virtual.
Brecha digital de zonas indígenas como factor de exclusión social
Authors: Martínez Dominguez Marlen , Gómez Navarro Dulce Ángelica
Published: December 2023

La brecha digital se reconoce como una forma de exclusión social que afecta en mayor medida a los pueblos originarios. En Oaxaca, por su alta composición de población indígena se observa un continuum histórico de desigualdades que se expresan en la pobreza, la marginación, la baja escolaridad y el bajo poder adquisitivo, que actúan como barreras para el acceso y uso de las TIC y enmarcan las brechas digitales. En este estudio se analizan los factores sociodemográficos, económicos, culturales y geográficos que inciden en el acceso y uso de las TIC por parte de la población indígena del estado, así como las políticas de inclusión digital emprendidas para el cierre de la brecha digital.

Los hallazgos revelan que la educación, el poder adquisitivo y las políticas de inclusión digital son condicionantes para fomentar el acceso y uso tecnológico. Se vislumbra la necesidad de diseñar y aplicar políticas digitales con la participación de los tres niveles de gobierno (federal, estatal y municipal) y agentes sociales locales, bajo un marco del reconocimiento de la diversidad cultural y lingüística, políticas más allá del carácter instrumentalista, que promuevan la inversión pública-privada en telecomunicaciones, además de seguir avanzando en mejorar el bienestar de la población indígena.
Reflexiones sobre modalidades pedagógicas, plataformización y educación en la universidad pública pospandemia
Authors: Pagola Lila Isabel , Zanotti Agustín , Grasso Mauricio
Published: December 2023

El artículo reúne reflexiones relacionadas con procesos de plataformización social y sus consecuencias en universidades públicas de Argentina. Nos ubicamos en un escenario post pandemia, donde una “nueva normalidad” nos permite una cierta distancia sobre el período de excepcionalidad pedagógica. Al mismo tiempo, se evidencian desafíos emergentes a la hora de experimentar con modalidades pedagógicas que superan las divisiones clásicas entre lo presencial y a distancia.

Comprendemos que la pandemia de COVID-19 precipitó una serie de tendencias preexistentes en el ámbito educativo. Por ese motivo, nos interesa reconstruir procesos macro que vienen instalándose desde larga data. Para ello, hacemos foco en ciertas dinámicas informacionales, en particular aquellas relacionadas a los avances de la plataformización en la última década, junto a experiencias e impresiones sobre la implementación en instituciones de educación superior en la provincia de Córdoba.  

Nuestras indagaciones dan cuenta, salvo importantes excepciones, de una falta de problematización y planificación de las nuevas infraestructuras digitales necesarias, frente a procesos estructurales de transformación de las prácticas sociales y educativas. 

Metodológicamente el trabajo se sustenta en aportes conceptuales de diversas fuentes, así como la sistematización de experiencias docentes y de gestión educativa.
El periódico ¡Adelante!
Authors: Barandiarán Luciano , Iturralde María E. , Funaro Fernando , Silva Ana
Published: December 2023

El artículo presenta los resultados de un proceso de investigación centrado en la digitalización y puesta en disponibilidad pública del archivo de ¡Adelante! El Periódico de la Usina Popular de Tandil, un órgano de prensa editado en la localidad bonaerense de Tandil, Argentina, entre 1934 y 1942. Dicha publicación nace en el proceso de creación de la Usina Popular, una entidad que buscó brindar un servicio accesible y de calidad para llevar energía eléctrica a los tandilenses. La digitalización de estos materiales de archivo y su puesta a disposición en repositorios de acceso abierto plantea, por un lado, una serie de interrogantes acerca de las relaciones que se establecen entre los procesos comunicacionales, las tecnologías digitales y las políticas públicas que pugnan llevarla adelante, al mismo tiempo que exigió la conformación de un equipo multidisciplinario que involucró el diálogo con las investigaciones históricas que contribuyen a la construcción de una historia de los medios de prensa de ciudades medias de la provincia de Buenos Aires.
Personality adjectives in Serbian Tweets: An opening
Authors: Čolović Petar , Bojanić Marija , Žunić Anastazia , Peres Alexandre José de Souza
Published: December 2023

There has been a great interest in investigating relations between personality and language use on the web or social media. Most of the recent studies are based on mining the users’ information available online and then using machine learning algorithms to predict their personality characteristics. On the other hand, a few studies have relied on the traditional lexical hypothesis when exploring personality under the assumption that personality-related attributes could be obtained from dictionaries. However, little is known about personality structure from Twitter - do data strictly reflect personality structure as represented by personality models, or as unique personality semantic patterns. The aim of the study was to assess and interpret the personality adjective-based structure contained in tweets. The data were collected from an open-access „Tweet-sr“ Serbian Twitter linguistic corpus (Ljubešić & Klubička, 2014). Latent Dirichlet Allocation, a topic modeling technique, was conducted to extract topics and cosine similarity was used as a measure to determine topic similarities, as well as topic-personality dimensions’s similarities. The results showed that the optimal solution comprised four non-overlapping topics reflecting specific semantic structures. Topics did not replicate trait constructs but were modestly related to them. The largest similarities were found with Extraversion and Agreeableness, pointing out the conceptual importance of these traits when describing interpersonal behavior. Also, no inter-topic differences in category distributions were found, with the evaluation terms being the second most frequent in three topics. Although tweets are short-form text messages, they have the potential to communicate socially relevant information through personality descriptors.
Dekadensi Moral Terhadap Degradasi Lingkungan di Daerah Aliran Sungai Cibanten
Authors: Sumintak Sumintak , Lenwinsky Sefti Wiwin , Irfan Ade
Published: December 2023

Penelitian ini berupaya untuk mengurai bentuk kerusakan lingkungan dan faktor penyebab terjadinya kerusakan lingkungan di Daerah Aliran Sungai Cibanten, Kota Serang, Provinsi Banten. Penelitian ini menggunakan metode kualitatif deskriptif mengamati aktivitas keagamaan dengan menggunakan pendekatan Fenomenologi Interpretatif mengamati setiap aktivitas pratik kepedulian lingkungan masyarakat yang menjadi objek penelitian. Adapun teknik pengumpulan data menggunakan beberapa cara yatiu dengan melakukan pengamatan, menyebar angket, dan melakukan wawancara mendalam pada informan untuk menggali informasi seputar data yang dibutuhkan. Hasil penelitian ini menunjukkan adanya dekadensi moral dalam hal perilaku masyarakat yang tidak peduli terhadap lingkungan dengan membuang sampah ke aliran Sungai Cibanten, hal ini dikarenan lemahnya iman dan kurangnya pengetahuan akan kepedulian lingkungan yang menjadi penyebab terjadinya bencana banjir dan rusaknya ekologi Sungai Cibanten. Dari fenomena ini diperlukan penanganan secara khusus untuk mengubah perilaku masyarakat, dengan menanamkan nilai-nilai spiritualitas keagamaan lewat pemahaman dari aktifitas kajian-kajian keagamaan agar dapat menghilangkan dekadensi moral berupa perilaku merusak lingkungan agar tidak terjadi degradasi lingkungan Sungai Cibanten.
Cartographic sources of the late XVIII–XIX centuries as a material for studying the system of settlement of the population in the Komi territory
Authors: Silin V.
Published: December 2023

The paper considers cartographic sources that can be the basis for studying the settlement of residents in the Komi territory. The significance of the results of the General Land Survey of the late XVIII century and cartographic sources compiled on their basis is emphasized. To study the settlement system, the importance of maps compiled under the leadership of I. A. Strelbitsky is determined. Data on the settlement of the Russians or Zyryans in each village of the region is provided based on the results of the Ethnographic Map of European Russia, published edited by A. F. Rittich.
On the issue of resettlement policy in the European North of Russia at the beginning of the XX century (case study of Arkhangelsk Province)
Authors: Kuratov O.
Published: December 2023

The paper deals with issues related to state measures in the field of resettlement policy in the territory of the European North of Russia at the beginning of the XX century (case study of Arkhangelsk Province). Particular attention is paid to the legal framework, political and economic factors that influenced the resettlement process. The main stages of the formation of the legal foundations of the resettlement policy of the Russian government during this period are also investigated, legislative decisions of the tsarist government and their significance are analyzed. The paper demonstrates the influence of immigrants on the methods and forms of management, as well as changes in state policy in the context of the growing national crisis.
Secondary specialized educational institutions of agricultural profile in the Komi ASSR in the 1950s : gender, age and national composition of students
Authors: Macuk A.
Published: December 2023

Based on archival sources, the paper considers the problems of age, gender and national composition of students of secondary specialized educational institutions that trained agricultural specialists in the Komi ASSR in the 1950s. It is concluded that a significant proportion of students were female. In the context of the age groups of students during the study period, the proportion of representatives of the oldest group, both among female and male students, increased. It is shown that representatives of many nationalities were trained in the educational institutions under study. However, in terms of the number of students, their ratio was unequal.
Does Food Elimination Based on Immunoglobulin G Antibodies Diminish Tension-Type Headache?
Authors: DURMAZ ÇELİK Fatma Nazlı , SENER Ozden
Published: December 2023

The aim was to evaluate if foods, against which patient has IgG antibodies, trigger tension type headache (TTH). 22 patients (8 male, 14 female; 8 chronic TTH, 14 frequent episodic TTH) were recruited. The study had four periods: cooperation, provocation, free diet month and elimination were determined. At the cooperation perido patients’ cooperation abilities were checked. All patients were screened for 271 different antibodies against foods using Imupro300. Thus a list of food sensitivity was described for each patient. In provocation period,those detected foods were added to diet. In elimination period, those foods were eliminated from the diet with false foods added. In free diet month, there were no restrictions. Patients recorded the number of the days with headache as well as headache frequency, severity and duration and analgesic intake. These headache features in cooperation, provocation and elimination periods were compared. In the elimination period there was a significant decrease in the number of days with headache, headache frequency and duration in all patients. A significant increase in these three features were observed in the provocation period. In chronic TTH patients, only the number of the days with headache significantly increased in provocation period. IgG antibodies against foods may have a role in TTH. Number of days with headache, headache frequency and duration can be decreased by eliminating related foods from the diet, and this can be a part of the treatment. IgG antibodies against foods may be one of the pathophysiological mechanisms triggering TTH.
Parametric identification of system regularity
Authors: Vityaz O.A.
Published: December 2023

Analysis of complicated systems can be executed using subsystem parameters and functions. The feedback systems can be taken as an example. Such approach is valid only if the regularity property of subsystems is not violated after their connection that is not always a case. At the paper the algebraic criteria of the system regularity are developed and the regularity property can be identified on the base of the subsystem parameters.
PLANO ESTRATÉGICO COMO UM PRODUTO DE INOVAÇÃO E GOVERNANÇA INSTITUCIONAL: A EXPERIÊNCIA DA TRANSIÇÃO/IMPLANTAÇÃO DA UFNT
Authors: Medeiros Ana Lúcia , Abreu Sousa Kleber , Matos Ribeiro Mariana , De Carvalho Silva Andréia
Published: December 2023

A Universidade Federal do Norte do Tocantins (UFNT) resultou do desmembramento da Universidade Federal do Tocantins (UFT). O processo de transição UFT/UFNT buscou conceder autonomia à nova universidade, demandando a criação de um modelo de governança e gestão. Esse modelo orientou desde a implantação dos grupos de trabalho  atuantes nos níveis tático e operacional até a elaboração dos documentos essenciais. Este estudo tem como objetivo analisar a utilização do Planejamento Estratégico Situacional (PES) na elaboração do primeiro Planejamento Estratégico (PE) da UFNT, considerando-o como um produto de inovação decorrente do modelo de governança empregado durante a transição da UFNT. Realizou-se uma pesquisa qualitativa, por meio de estudo de caso e observação participante. A análise de conteúdo foi utilizada para analisar as informações coletadas. A hipótese é que a UFNT aplicou o PES como método na elaboração do PE. Embora as informações coletadas não atribuam explicitamente ao PES como o método aplicado, é possível observar uma forte influência desse método. Este estudo contribui para a compreensão do processo de construção do Planejamento Estratégico em uma instituição pública de ensino superior, destacando a vantagem metodológica do PES, especialmente em contextos acadêmicos complexos e participativos, como a transição e implantação de uma universidade.
INOVAÇÕES AMBIENTAIS NA INDÚSTRIA DE MINÉRIO DE FERRO: PERSPECTIVA DE ENERGIAS
Authors: Paiva Apolinario Raissa Helena , Saraiva de Souza Maria Tereza , Soares da Silva Luciana
Published: December 2023

Como o setor de mineração é intensivo no consumo de energia, os recursos renováveis, apresentam-se como soluções para desafios energéticos presentes na indústria de mineração. Apesar da difusão e a adoção de inovações tecnológicas serem uma alternativa para lidar com os desafios energéticos, sua aplicação ainda enfrenta dificuldades devido a complexidades e resultados a longo prazo. O objetivo do estudo é analisar a difusão e a adoção de inovações ambientais relacionadas às energias renováveis no setor de minério de ferro brasileiro. Essa pesquisa utilizou uma abordagem metodológica qualitativa, por meio do método de estudo de casos múltiplos, com instrumento de coleta de dados: entrevistas semiestruturadas e documentos públicos. Como contribuição apresentam-se: os aspectos ambientais e operacionais do setor de minério de ferro; potenciais tecnologias de energias renováveis utilizadas no setor de mineração de ferro; e orientação para gestores da área de sustentabilidade, assim como criadores de políticas públicas do tema. As principais estratégias utilizadas pelo setor são: eficiência energética e descarbonização de energia. Porém, as tecnologias de eficiência energética e iniciativas ambientais para mitigação das emissões de GEE ainda são equacionadas entre incertezas dos riscos de investimentos e benefícios ambientais diretos e indiretos.
Green Human Resource Management as a Catalyst for Sustainable Performance: Unveiling the Role of Green Innovations
Authors: Zihan Wang , Makhbul Zafir khan Mohamed
Published: December 2023

Abstruct Green Human Resource Management (GHRM) has emerged as an essential strategy for achieving environmental sustainability within organizations. However, there remains a significant gap in understanding its direct impact on sustainable performance. This study seeks to address these gaps by investigating the relationship between GHRM and sustainable performance, with a focus on the mediating role of green innovation and the moderating influence of transformational leadership. A cross-sectional study was conducted among Malaysian small and medium-sized enterprises (SMEs) to explore the interrelationships between Green HRM, green process and product innovation, sustainability, and the role of sustainable leadership. The study's findings reveal a positive and significant relationship between green HRM practices and sustainability, encompassing environmental, economic, and social aspects. The findings suggest that management support for environmental initiatives is a critical factor in enhancing the effectiveness and spread of green innovations, emphasizing the importance of GHM in the broader context of organizational change and sustainability. In addition, the study underscores the critical role of transformative leadership in fostering sustainable practices, particularly the significant moderator role of responsible leadership in driving sustainable business practices. In summary, this study provides a roadmap for businesses, particularly SMEs, to leverage HGRM as a strategic tool in their pursuit of sustainability.
Structural Characterization and Antidepressant-Like Effects of Polygonum sibiricum Polysaccharides Associated with Regulating Microglial Polarization in Cums-Induced Zebrafish
Authors: Zhang Ying yu , Wang Dan yang , Liu Jia meng , Bai Ya juan , Fan Bei , Lu Cong , Wang Feng zhong
Published: December 2023

: Background: The polysaccharides are one of the main active ingredients of Polygonum sibiricum (PSP), which is a traditional food and medicine homologues in China. The antidepressant-like effects of PSP and its underlying mechanisms remain to be studied in depth, especially the regulation of microglial polarization. Methods: The chemical composition and structural characteristics of PSP was determined firstly. The CUMS procedure was carried out to the zebrafish for 5 weeks and PSP were immersed administration for 9 days (1 h/d). The body weight of zebrafish was monitored and the behavioral tests, including the novel tank test and light and dark tank test, were performed to evaluate the antidepressant-like effects of PSP. Then the function of HPI axis, the levels of peripheral inflammation, neuronal and blood-brain barrier damage in mesencephalon and telencephalon and the mRNA expression of M1/M2 phenotype genes in brain were examined. Results: PSP samples had the typical structure characteristics of polysaccharide, consisting of glucose, mannose and galactose with the average Mw 20.48 kDa, which owned a porous and agglomerated morphology. Compared with untreated zebrafish, the depression-like behaviors of CUMS-induced zebrafish were significantly attenuated. PSP significantly decreased the levels of cortisol and the pro-inflammatory cytokines and increased the levels of the anti-inflammatory cytokines in the body of CUMS-induced depressive zebrafish. Furthermore, neuronal and blood-brain barrier damage in mesencephalon and telencephalon and the mRNA expression of M1/M2 phenotype genes in brain were remarkably reversed by PSP. Conclusion: These findings indicated that the antidepressant-like effects of PSP were related to alter the HPI axis hyperactivation, suppress peripheral inflammation, inhibit neuroinflammation induced by microglia hyperactivation, and modulate microglial M1/M2 polarization. The current study provides foundation to the future exploitation of PSP in the functional foods of emotional regulation.
The efficacy and safety of pyrotinib in treating HER2-positive metastatic breast cancer patients:A multi-center study
Authors: Gao Min , Li Yuhui , Dong Qingfen , Chen Fang , Fu Chao , Liu Shuaishuai , Liu Shuai , Ju Xiao , Zheng Xin , Lu Jie
Published: December 2023

Purpose: To investigate the efficacy and safety of pyrotinib in treating patients with HER2-positive metastatic breast cancers (MBC).
Patients and Methods: We performed a multi-center retrospective study, and the HER2-positive MBC patients were recruited. The progression-free survival (PFS), and overall survival (OS) were considered in the assessment of treatment outcomes.
Results: 275 female patients were enrolled. The objective response rate (ORR) and disease control rate (DCR) , were found in 154 of 275 (56%) and in 205 of 275 (75%), respectively. The median effective time was 45 days. The median follow-up time was 41 months.The median time for progression and OS were 16 and 35 months. The PFS of survival general population at 1-year, 2-year and 3-year was 72.7% , 40.4%, and 33.1%, respectively, whle the OS was 91.6% , 78.2%, and 63.2%, respectively. The PFS of brain metastases patients at 1-3-year was 67.3%, 25% and 13.5%, while, the OS was 84.6%, 63.5% and 46.2%.
Conclusion: Pyrotinib mono-therapy showed equivalent local control rates, PFS and OS, compared with the combined therapy of pyrotinib and chemotherapy in both the general population and patients with brain metastases, with manageable toxicity, highlighting the significance of mono-therapy of pyrotinib in treating HER-2 positive MBC.
An Inactivated Rabies-based Lassa Fever Virus Vaccine Candidate, LASSARAB, Protects Nonhuman Primates from Lethal Disease
Authors: Schnell Matthias , Scher Gabrielle , Yankowski Catherine , Kurup Drishya , Josleynl Nicole , Wilkinson Eric , Wells Jay , Steffens Jesse , Lynn Ginger , Vantongeren Sean , Zeng Xiankun (Kevin) , Twenhafel Nancy , Cashman Kathleen
Published: December 2023

Lassa fever virus (LASV), a member of the Arenavirus family, is the etiological agent of Lassa fever, a severe hemorrhagic disease that causes considerable morbidity and mortality in the endemic areas of West Africa. LASV is a rodent-borne CDC Tier One biological threat agent and is on the World Health Organization’s (WHO) Priority Pathogen list. Currently, no FDA-licensed vaccines or specific therapeutics are available. Here, we describe the efficacy of a deactivated rabies virus (RABV)-based vaccine encoding the glycoprotein precursor (GPC) of LASV (LASSARAB). Nonhuman primates (NHPs) were administered a two-dose regimen of LASSARAB or an irrelevant RABV-based vaccine to serve as a negative control. NHPs immunized with LASSARAB developed strong humoral responses to LASV-GPC. Upon challenge, NHPs vaccinated with LASSARAB survived to the study endpoint, whereas NHPs in the control group did not. This study demonstrates that LASSARAB is a worthy candidate for continued development.
Prediction and assessment of meteorological drought characteristics in China based on a future climate model
Authors: Huang Tingting , Liu Yu , Jia Zhifeng , Zhang Zengxin , Ma Xiaoyi
Published: December 2023

Under the background of a warm and humid climate, predicting and evaluating the future pattern of wet and dry change characteristics in watersheds is of great research significance. Based on the Geophysical Fluid Dynamics Laboratory earth system coupling model and GFDL‒ESM2M climate model, which is highly applicable in China, the characteristics of standardized precipitation evapotranspiration index (SPEI) variations in China at annual and monthly scales was assessed based on downscaled climate data under four typical representative concentration pathway scenarios. The results are as follows: (1) In the future, the annual scale meteorological drought trend in China will become more "aridity", and the monthly scale dry and wet changes will be non-uniform. With the increase of carbon dioxide emission concentration, the proportion of regional aridity in China will be increased in the future. (2) The proportion of wetting area will decrease, and extreme weather events are more likely to occur. In the future, the drought duration in China will mainly be 1–4 months. (3) The return period of drought in large areas of the country will be 1–50 years, and the return period in some western regions even exceed 500 years.
Promoting the implementation of a computer-tailored physical activity intervention: Development and feasibility testing of an implementation intervention
Authors: Peels Denise A. , Boekhout Janet M. , Nassau Femke Van , Lechner Lilian , Bolman Catherine A.W. , Berendsen Brenda A.J.
Published: December 2023

Background
Although there are many proven effective physical activity (PA) interventions for older adults, implementation in a real world setting is often limited. This study describes the systematic development of a multifaceted implementation intervention targeting the implementation of an evidence-based computer-tailored PA intervention and evaluates its use and feasibility.
Methods
The implementation intervention was developed following the Intervention Mapping (IM) protocol, supplemented with insights from implementation science literature. The implementation intervention targets the municipal healthcare policy advisors, as an important implementation stakeholder in Dutch healthcare system. The feasibility of the implementation intervention was studied among these stakeholders using a pretest-posttest design within 8 municipal healthcare settings. Quantitative questionnaires were used to assess task performance (i.e. achievement of performance objectives), and utilization of implementation strategies (as part of the intervention). Furthermore, changes in implementation determinants were studied by gathering quantitative data before, during and after applying the implementation intervention within a one-year period. Additionally, semi-structured interviews with stakeholders assessed their considerations regarding the feasibility of the implementation intervention.
Results
A multi-faceted implementation intervention was developed in which implementation strategies (e.g. funding, educational materials, meetings, building a coalition) were selected to target the most relevant identified implementation determinants. Most implementation strategies were used as intended. Execution of performance objectives for adoption and implementation was relatively high (75–100%). Maintenance objectives were executed to a lesser degree (13–63%). No positive changes in implementation determinants were found. None of the stakeholders decided to continue implementation of the PA intervention further, mainly due to the unforeseen amount of labour and the disappointing reach of end-users.
Conclusion
The current study highlights the importance of a thorough feasibility study in addition to the use of IM. Although feasibility results may have demonstrated that stakeholders broadly accepted the implementation intervention, implementation determinants did not change favorably, and stakeholders had no plans to continue the PA intervention. Yet, choices made during the development of the implementation intervention (i.e. the operationalization of Implementation Mapping) might not have been optimal. The current study describes important lessons learned when developing an implementation intervention, and provides recommendations for developers of future implementation interventions.
Comparison of short-term complications and long-term prognostic of pancreaticoduodenectomy with and without preoperative biliary drainage in malignant obstructive jaundice
Authors: Qu Guangzhen , Lyu Shao-Cheng , Kou Jiantao , Gao Kun , Lang Ren
Published: December 2023

Background: Malignant obstructive jaundice is a common symptom in patients with periampullary cancer. The impact of PBD on short-term complications after pancreaticoduodenectomy (PD) and the risk factors affecting long-term survival for periampullary cancer still unravel.
Methods: We retrospectively collected relevant data of patients with periampullary cancer who underwent pancreaticoduodenectomy for obstructive jaundice from 2017 to 2022. We divided them into PBD group and Non PBD group based on whether preoperative biliary drainage was performed. The postoperative complications between the PBD group and the Non-PBD group was compared. Binary logistic analysis is used to identify relevant risk factors affecting complications after PD. The differences in the incidence of postoperative complications among different biliary drainage methods and duration of biliary drainage were also analyzed. Afterwards, univariate Cox and multivariate Cox regression analyses were performed to identify risk factors associated with prognosis of pancreatic cancer, common bile duct cancer, and Vater ampullary cancer.
Results: A total of 165 patients were included in the analysis (PBD=84, Non PBD=81). There was no difference in age, gender, BMI, American Society of Anesthesiologists (ASA), and disease history between the PBD group and the Non PBD group. The incidence of postoperative complications in the PBD group was 55%, while in the Non PBD group it was 51%, with no statistical discrepancy (P = 0.10). The positive rate of postoperative drainage fluid culture in the PBD group was slightly higher than that in the Non-PBD group (19% versus 10%, P=0.095). Preoperative total bilirubin>200μmol/L (OR = 32.545, P ＜0.001) and prolonged surgical duration (OR = 1.006, P = 0.008) are independent risk factors for postoperative complications in PD. There was no discrepancy in the postoperative complications between the PBD ≤ 14 day subgroup and the PBD>14 day subgroup (P = 0.5), as well as between PTCD and ERCP drainage methods (P = 0.8). PBD and preoperative total bilirubin do not affect long-term survival after surgery for periampullary cancer.
Conclusions
Preoperative biliary drainage does not affect the incidence of postoperative complications in periampullary cancer with malignant obstructive jaundice, nor does it affect its long-term survival. Preoperative total bilirubin > 200μmol/L is an independent risk factor affecting the occurrence of complications after PD. The positive rate of postoperative drainage fluid bacterial culture in the PBD group is slightly higher than that in the Non-PBD group. Poor tumor differentiation and vein resection are common risk factors for long-term survival of pancreatic cancer and common bile duct cancer after PD.
Relationship between alveolar bone thickness, root apex position, and cephalometric skeletal indexes in the upper anterior teeth of adults with Class Ⅱ malocclusion.
Authors: Zheng Hui , Cui Shuxia
Published: December 2023

Objectives
To measure the alveolar bone thickness and root apex position in the upper anterior teeth of adults with Class Ⅱ malocclusion, and to explore the correlation with the corresponding cephalometric skeletal indexes.
Materials and Methods
Retrospective data collection was done on 90 adult patients with Class Ⅱ malocclusion. Measurement of sagittal skeletal patterns (SNA, SNB, ANB), vertical skeletal patterns (GoGn-SN), labial, lingual and total alveolar bone thickness in the root apex area (Tlabial, Tlingual, Ttotal), the labial, lingual and total rotation range of root (Rlabial, Rlingual, Rtotal), calculating root apex position (Pdistance, Pangle), and conducting correlation research.
Results
Tlabial(1.08 ± 0.96mm) and Rlabial (8.65 ± 7.33°) were significantly smaller then Tlingual(5.07 ± 1.7mm) and Rlingual(35.68 ± 14.82°) (P < 0.01) respectively; Ttotal was 6.15 ± 2.06mm, and Rtotal was 44.33 ± 14.38°; The maxillary central incisor root apex was situated at about 20% of the labial side of the alveolar bone (Pdistance: 19.04 ± 14.58%, Pangle: 21.10 ± 15.64%). Pearson correlation showed that: Ttotal, Rlingual and Rtotal were negatively correlated with GoGn-SN (r=-0.415, P < 0.01; r=-0.358, P < 0.05; r=-0.444, -0.411, P < 0.01); Ttotal, Rlingual and Rtotal were positively correlated with SNB (r = 0.316, P < 0.05; r = 0.421, P < 0.01; r = 0.476, P < 0.01).
Conclusions
In Class Ⅱ malocclusion the root apex is located on the labial side of the alveolar bone, and the thickness of the alveolar bone on the labial side is thin. The labial side of the maxillary incisor and the total alveolar bone thickness should be carefully examined in patients with high mandibular plane angle and mandibular retraction.
Clinical Relevance:
The study shows that it is important to evaluate the alveolar bone thickness and root apex position before orthodontic treatment, and to guide clinical practice from cephalometric measurement.