bluuebunny/crossref_metadata_2025 huggingface dataset:
Open eye injury. Perceived and real difficulties of surgery
Authors:   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Kaluga, Russia, Tereshchenko A.V. ,   Medical Institute of the Federal State Budgetary Educational Institution of Higher Education Kaluga State University named after K.E. Tsiolkovski, Kaluga, Russia, Shilov N.M. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Kaluga, Russia, Yudina N.N. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Kaluga, Russia, Plakhotniy M.A. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Kaluga, Russia, Buldygin A.A. ,   Kaluga branch of the S.Fyodorov Eye Microsurgery Federal State Institution, Kaluga, Russia
Published: June 2024

Purpose. To analyze two clinical cases of open eye injury after penetrating sclerocorneal injury. Material and methods. Both patients were admitted to the clinic after a penetrating sclerocorneal wound with a sharp object 2–3 hours after the injury. In both cases, primary surgical treatment and optical reconstructive surgery were performed simultaneously. On average, the duration of operations varied from 6 hours to 8 hours (total of primary surgical treatment + optical-reconstructive surgery). Results. In the first case, a complete anatomical comparison of all structures and membranes of the eye. The optimal volume of intervention was carried out, and all conditions were created for final reconstructive surgery. The rehabilitation period is 7 months. In the second case, it was possible to completely seal the eyeball, match all the ocular structures that were damaged during the injury, and achieve anatomical correspondence. Carefully performed simultaneous primary surgical treatment and optical reconstructive surgery allowed us to effectively complete silicone tamponade after 4 months, as well as lamellar keratoplasty after 7 months. The rehabilitation period is 14 months. Conclusion. An individual approach to each open eye injury with one-stage primary surgical treatment and optical-reconstructive surgery makes it possible to stabilize the pathological processes that are triggered during the injury, achieve maximum comparison of the anatomical structures and membranes of the eye, eliminate the consequences of injury with minimal surgical complications, and create favorable conditions for subsequent (if necessary) reconstructive stages, to obtain maximum functional results.
Tactics of surgical treatment of a patient with non-penetrating corneal trauma after previous FemtoLASIK
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd Branch, Volgograd, Russian Federation, Breev V.A. , Solodkova E.G. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd Branch, Volgograd, Russian Federation, Sibakin D.D. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd Branch, Volgograd, Russian Federation
Published: June 2024

Abstract Tactics of surgical treatment of a patient with non-penetrating corneal trauma after previous FemtoLASIK V.A. Breev, E.G. Solodkova, D.D. Sibakin S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd Branch, Volgograd, Russian Federation Purpose. To present the tactics of surgical treatment of the patient with non-penetrating corneal trauma after previously undergone FemtoLasik. Methods. The patient, operated by FemtoLASIK for middle degree myopia, had non-penetrating corneal trauma of the right eye. When applying to the Clinic of Volgograd branch he underwent corneal flap repositioning with removal of multiple corneal foreign bodies. Before and after the operation the patient underwent standard ophthalmologic examination. Results. According to the examination data, the uncorrected visual acuity of the right eye was reduced to 0.3 due to dislocation and linear defect of the corneal flap, multiple corneal foreign bodies, corneal opacity and mixed astigmatism. In 1 month after the surgical treatment there was noted restoration of transparency, correct position and integrity of the corneal flap, absence of corneal foreign bodies and increase of uncorrected visual acuity of the right eye up to 0.5. Conclusion. The correct sequence of surgical actions after trauma against the background of previously performed FemtolASIK provides qualitative corneal flap repositioning and restoration of visual functions. Key words: non-penetrating corneal trauma, corneal flap repositioning, FemtoLASIK For citation: Breev V.A., Solodkova E.G., Sibakin D.D. Tactics of surgical treatment of a patient with non-penetrating corneal trauma after previous FemtoLASIK.
Comparing parameterized and self-consistent approaches to ab inito CQED for electronic strong coupling
Authors: Manderna Ruby , Vu Nam , Foley Jonathan
Published: June 2024

Molecules under strong or ultra-strong light-matter coupling present an intriguing route to modify chemical structure, properties, and reactivity. A rigorous theoretical treatment of such systems requires handling matter and photon degrees of freedom on an equal quantum mechanical footing. In the regime of molecular electronic strong or ultra-strong coupling to one or a few molecules, it is desirable to treat the molecular electronic degrees of freedom using the tools of ab initio quantum chemistry, yielding an approach referred to as ab initio cavity quantum electrodynamics (ai-QED), where the photon degrees of freedom are treated at the level of cavity quantum electrodynamics. In this letter, we analyze two complementary approaches to ai-QED: (1) parameterized CQED (pQED), a two-step approach where the matter degrees of freedom are computed using existing electronic structure theories, enabling the construction of rigorous ai-QED Hamiltonians in a basis of many-electron eigenstates, and (2) self-consistent CQED (scQED), a one-step approach where electronic structure methods are generalized to include coupling between electronic and photon degrees of freedom. Although these approaches are equivalent in their exact limits, we identify a disparity between the projection of the two-body dipole self-energy operator that appears in the pQED approach and its exact counterpart in the scQED approach. We provide a theoretical argument that this disparity resolves only under the limit of a complete orbital basis and a complete many-electron basis for the projection. We present numerical results highlighting this disparity and its resolution in simple molecular systems, where it is possible to approach these two complete basis limits simultaneously. Additionally, we examine and compare the practical issue of computational cost required to converge each approach towards the complete orbital and many-electron bases.
In situ complexation of sgRNA and Cas12a improves the performance of a one-pot RPA–CRISPR-Cas12 assay
Authors: Lesinski Jake M. , Moragues Thomas , Mathur Prerit , Shen Yang , Paganini Carolina , Bezinge Léonard , Verberckmoes Bo , Van Eenooghe Bodine , Stavrakis Stavros , deMello Andrew J. , Richards Daniel A.
Published: June 2024

Due to their ability to selectively target pathogen-specific nucleic acids, CRISPR-Cas systems are increasingly being employed as diagnostic tools. “One pot” assays that combine nucleic acid amplification and CRISPR-Cas systems (NAAT–CRISPR-Cas) in a single step have emerged as one of the most popular CRISPR-Cas biosensing formats. However, operational simplicity comes at a cost, with one-pot assays typically being less sensitive than corresponding two-step NAAT–CRISPR-Cas assays and often failing to detect targets at low concentrations. It is thought that these performance reductions result from the competition between the two enzymatic processes driving the assay, namely Cas-mediated cis-cleavage and polymerase-mediated amplification of the target DNA. Herein, we describe a novel one-pot RPA–Cas12a assay that circumvents this issue by leveraging in situ complexation of the target-specific sgRNA and Cas12a to purposefully limit the concentration of active Cas12a during the early stages of the assay. Using a clinically relevant assay against a DNA target for HPV-16, we show how this in situ format reduces competition between target cleavage and amplification and engenders significant improvements in detection limit when compared to the traditional one-pot assay format, even in patient-derived samples. Finally, to gain further insight into the assay, we use experimental data to formulate a mechanistic model describing the competition between the Cas enzyme and nucleic acid amplification. These findings suggest that purposefully limiting cis-cleavage rates of Cas proteins is a viable strategy for improving the performance of one-pot NAAT–CRISPR-Cas assays.
Synthesis of high surface area Cu/SiO2 nanofiber catalysts for non-oxidative ethanol dehydrogenation
Authors: Pokorny Tomas , Kral Zdenek , Machac Petr , Moravec Zdenek , Simonikova Lucie , Kundrat Vojtech , Styskalik Ales , Pinkas Jiri
Published: June 2024

Amidst growing concerns over the environmental impact of petroleum-based industries and their contribution to global ecological challenges, there is a pressing need for sustainable alternatives in chemical synthesis. This study addresses this imperative by exploring an innovative catalytic approach for the eco-friendly production of acetaldehyde from ethanol, a crucial chemical feedstock. Catalysts utilized so far perform poorly due to their low stability. Supported copper nanoparticles at higher temperatures suffer from the rapid deactivation caused by nanoparticles sintering and reduction of active sites by coking. To address this issue, the advanced copper nanoparticle-decorated silica nanofibres (107 nm in diameter) with outstanding surface area (700 m2 g−1) were synthesized and tested, showing enhanced stability in comparison to benchmark (Aerosil 300 SiO2/Cu). Two approaches were compared for the preparation of copper catalyst, i.e., dry impregnation and one-pot synthesis. Remarkably, the dry-impregnated DI-9.4 sample at 325 °C after 100 h maintained over 66 % of ethanol conversion with 99 % selectivity to acetaldehyde (acetaldehyde productivity: 3.09 g g h–1). This stability values surpass the benchmark catalyst, which dropped to 40 % of ethanol conversion. Our findings highlight the potential of the superior morphological advantage of electrospun SiO2 nanofibers as an efficient catalyst.
Evolutionary Optimization of the Reduced Gas-phase Isoprene Oxidation Mechanism
Authors: Chakraborty Arijit , Wiser Forwood , Sen Siddhartha , McNeill V. Faye , Venkatasubramanian Venkat
Published: June 2024

Atmospheric chemistry is highly complex, and significant reductions in the size of the chemical mechanism are required to simulate the atmosphere. One of the bottlenecks in creating reduced models is identifying optimal numerical parameters. This process has been difficult to automate, and often relies on manual testing. In this work, we present the application of particle swarm optimization (PSO) towards optimizing the stoichiometric coefficients and rate constants of a reduced isoprene atmospheric oxidation mechanism. Using PSO, we are able to achieve up to 27% improvement in our accuracy metric when compared to a manually tuned reduced mechanism, leading to a significantly optimized final mechanism. This work demonstrates PSO as a promising and thus far underutilized tool for atmospheric chemical mechanism development.
Caso investigativo na formação continuada de professores: discutindo a relação da prática experimental na sala de aula
Authors: Baffa Lourenço Ariane , Abreu de Andrade Viviane , Dos Santos Moraes Sergio , Cristina da Cruz Luana , Cesar Ferreira Fernando
Published: June 2024

Este trabalho apresenta o emprego do método estudo de caso em contexto de formação continuada de professores de Física à criação de um ambiente de aprendizagem e reflexão sobre a prática experimental em sala de aula. O Estudo foi desenvolvido em uma disciplina oferecida por curso de mestrado profissional do Ensino de Física voltado à formação de professores que atuam na Educação Básica brasileira. Participaram da investigação 5 professores/mestrandos, os quais foram apresentados, durante a disciplina, a referenciais teóricos sobre prática experimental e o método de estudo de caso. Em seguida, os professores/mestrandos elaboraram, de forma individual, um caso investigativo sobre a prática experimental, considerando os referenciais previamente apresentados e os apresentaram aos colegas e a docente da disciplina, criando um espaço de discussão e reflexão da prática experimental em contexto de sala de aula. Os casos produzidos foram de natureza distinta, envolvendo as modalidades de atividades experimentais: atividades do tipo demonstração, de investigação e de verificação. A fonte de inspiração dos professores/mestrandos para o desenvolver dos casos foi sua própria experiência, ou seja, partiram de um problema real de seu contexto de formação e/ou atuação profissional. A análise dos dados revela a relevância e a consonância desses resultados com os objetivos da formação profissional continuada de professores, uma vez que esta deve promover a valorização da experiência do aluno-professor e estimular a sua profissionalização permanente de forma contextualizada. Ademais, os dados indicam a aplicação coerente, por parte dos mestrandos, de pressupostos teóricos da atividade experimental à sua prática docente.
UMA PROPOSTA DE ESTUDO COMPARATIVO ENTRE AULAS EXPOSITIVAS E ABORDAGENS INVESTIGATIVAS NO ENSINO DE FÍSICA
Authors: Nóbrega Bernardino Candice , Santos Antonio Marques dos
Published: June 2024

Este artigo apresenta uma proposta de estudo comparativo entre as abordagens expositiva e investigativa no ensino de física. O objetivo do estudo é analisar a eficácia dessas duas abordagens no processo de aprendizagem dos alunos e identificar as vantagens e desvantagens de cada uma. A metodologia proposta consiste na realização de um experimento controlado com dois grupos de alunos. Um grupo receberá uma palestra tradicional onde o professor apresenta os conceitos teóricos da física de forma linear e os alunos recebem o conhecimento de forma passiva. Outro grupo é incentivado a participar de aulas com abordagem investigativa para investigar, questionar e apurar fenômenos físicos por meio de atividades práticas, experimentos e resolução de problemas. Ao longo do estudo, dados quantitativos e qualitativos são coletados por meio de testes de conhecimento, pesquisas de satisfação do aluno e observações em sala de aula. Esses dados foram analisados usando métodos estatísticos para determinar diferenças significativas entre os dois grupos. Espera-se que os resultados deste estudo forneçam informações sobre a eficácia de uma abordagem exploratória em comparação com as aulas de física. Pretende-se ainda apurar as preferências dos alunos em relação aos métodos de ensino utilizados, e verificar se uma abordagem exploratória contribui para uma melhor compreensão dos conceitos físicos e motivação para a aprendizagem.
PENGARUH ROA, ROE, DAN NIM TERHADAP HARGA SAHAM PADA PERUSAHAAN PT BANK CENTRAL ASIA TBK. PERIODE 2012-2021
Authors: Putri Bunga Ismaya , Putri Maharani , Octavia Ayu Nurafni
Published: June 2024

Penlitian ini bertujuan untuk mengetahui pengaruh Return On asset (ROA),
Return On Equity (ROE), dan Net Interest Margin (NIM) terhadap harga

saham pada perusahaan PT. Bank Central asia, Tbk. periode 2012-2021

pertriwulan. Penelitian ini menggunakan metode kuantitatif dengan teknik

analisis data yang digunakan dalam penelitian yaitu analisis regresi linier

berganda dengan uji hipotesis menggunakan uji statistik menguji secara

parsial masing masing variabel, serta uji F untuk variabel independen

secara simultan terhadap variabel independent. Data diolah menggunakan

program SPSS. Hasil penelitian menunjukan bahwa ROA nilai

signifikansinya sebesar 0,043 < 0,05 maka secara parsial berpengaruh

signifikan terhadap harga saham, sedangkan ROE nilai signifiikansinya

0,843 >0,05 maka seacra parsial tidak ada pengaruh terhadap harga saham

dan NIM nilai signifikansinya sebesar 0,743 > 0,05 maka secara parsial

tidak ada pengaruh terhadap harga saham. Secara simultan ROA, ROE,

NIM, berpengaruh terhadap harga saham.

Kata Kunci :

ROA; ROE; NIM; Harga Saham.
Imaging Ancient Images: Challenges in Analogous and Digital Documentation of Geoglyphs on Lateritic Plateaus of Konkan, India
Authors:   Center for Heritage Conservation, CEPT Research and Development Foundation, CEPT University, Ahmedabad, Gujarat, India, Mane Mrudula M. , Garge Tejas Madan ,   Department of Archaeology and Museums, Government of Maharashtra, India, Sukumaran Prabhin ,   Dr K C Patel Research and Development Centre, Charotar University of Science and Technology (CHARUSAT), Desai Jigna ,   Center For Heritage Conservation at CEPT Research and Development Foundation, CEPT University, Ahmedabad, Gujarat, India, Chauhan Parth R. ,   Department of Humanities & Social Science, Indian Institute of Science Education and Research (IISER), Mohali, Punjab, India
Published: June 2024

In a part of western India, rock art (of unknown age) was executed on horizontal lateritic surfaces depicting abstract, human and animal figures. This paper discusses methodological and interpretative challenges confronted during manual and digital documentation attempts at the select sites of Devache Gothane, Ukshi, Devohasol and Barsu. The need for a multidisciplinary approach is highlighted to address the questions - What type of documentation is required for a truthful or accurate representation of geoglyphs for further scientific investigation? And how to integrate ethical practices for knowledge exchange between local communities and academia during documentation processes?
Reassessing the conservation and restoration activities of Champa temples in Ninh Thuan province, Vietnam | Đánh giá lại hoạt động bào tồn và trùng tu đền tháp Champa ở tỉnh Ninh Thuận, Việt Nam
Authors:   Faculty of Tourism, Nguyen Tat Thanh University, Ho Chi Minh, Vietnam, Dai Tuyen Quang
Published: June 2024

The preservation and restoration of Champa temples in Ninh Thuan Province, Vietnam, have been the subject of increasing attention from the government and conservation experts. This study aims to reevaluate the current conservation and restoration efforts and provide recommendations for ensuring the sustainable preservation of these important cultural relics. The research data were gathered between 2010 and 2019, using a combination of archival documents, site surveys, and ethnographic fieldwork. The study highlights that Champa temples are valuable national and special national heritage sites, receiving significant support from the State of Vietnam to safeguard and protect these historical structures. Despite the substantial conservation and management efforts, certain conservation methods have resulted in some limitations, such as testing directly on the body of the tower and modifying the architectural features of the sculptures and new constructions of the Champa temple, which could alter the core meaning of these sites. Therefore, this study suggests that conservationists and researchers must closely collaborate with the Cham community to understand and appreciate the significance of the Champa heritage, while also preserving its cultural and historical authenticity. Overall, this research proposes a reconsideration of the conservation approach, taking into account the cultural context, community values, and long-term sustainability of the Champa temples in Ninh Thuan Province, Vietnam. Nghiên cứu này đánh giá lại việc trùng tu và bảo tồn các đền tháp Champa ở Ninh Thuận và gợi mở một số đề xuất nhằm thực hiện công tác bảo tồn một cách đảm bảo nhất trong tương lai. Dữ liệu nghiên cứu được thực hiện từ năm 2010 đến năm 2019 bằng việc áp dụng nhiều phương pháp khác nhau bao gồm dữ liệu văn bản, khảo sát thực địa và nghiên cứu điền dã dân tộc học. Nghiên cứu này cho thấy rằng các đền tháp Champa đã nhận được sự quan tâm rất lớn của Nhà nước Việt Nam nên được công nhận là di sản quốc gia và di sản quốc gia đặc biệt. Bên cạnh đó, Việt Nam cũng đã có những biện pháp để bảo tồn và bảo vệ các di tích này. Do đó, có một số kiến trúc và nghệ thuật đã và đang dần được duy trì và bảo vệ. Tuy nhiên, những nỗ lực bảo tồn và quản lý đã có một số vấn đề giới hạn từ cách tiếp cận bảo tồn của các chuyên gia trùng tu. Cụ thể, thử nghiệm trực tiếp trên thân tháp, thay đổi nhiều đặc điểm kiến trúc điêu khắc và xây mới hướng lên tháp Champa đã làm thay đổi ý nghĩa cốt lõi của đền tháp Champa. Nghiên cứu này khẳng định rằng, các nhà nghiên cứu và trung tu đền Champa cần phải nghiên cứu một cách kỹ lượng và gắn với cộng đồng Chăm để đảm bảo được tính nguyên trạng và ý nghĩa di sản Champa.
Physical Education Teacher Perception in Conducting Online Learning Activities during Covid-19 Pandemic
Authors: Hartoto Setiyo , Nurhasan Nurhasan , Maksum Ali , Al Ardha Muchamad Arif , Hidayat Taufiq , Hamdani Hamdani , Yang Chung Bing
Published: June 2024

The first covid-19 case was founded in Indonesia on March 2020. Then, Indonesian government then announced the study from home policy a few weeks afterward. The teaching learning activity needs to be conducted by online teaching. This study aimed to evaluate the online teaching process at Physical Education subject. There were 447 physical education teachers were involved in this study. The Physical Education Online Learning Scale (PEOLS) was developed and used as research instrument in this study. The construct validity and reliability of PEOLS are 63.288 % and α = .880. The data were analyzed by independent t-tens and one-way anova based on gender (male/female), school status (public/private), and age groups. The result, there are significant different on age and teaching place. Younger teachers are facing less difficulties in online teaching (sig. >0.05). Furthermore, the teachers who teach in the public area have more beneficial in their teaching process (sig. >0.05). In Conclusion, the online teaching learning activity during covid-19 pandemic were influenced by the teachers’ capability of using internet and the accessibility of online teaching facility.
Pengembangan Tes Instrument Identifikasi Bakat BolaBasket Untuk Anak Usia Dini
Authors: Susanto Nugroho , Wiriadinata Windo , Rusdiawan Afif
Published: June 2024

Penelitian ini bertujuan untuk mengembangkan tes keterampilan bolabasket anak usia dini yang valid dan reliabel berdasarkan dalam indikator keterampilan bolabasket. Jenis penelitian ini adalah R and D ( research and development) dengan pendekatan melalui tes dan pengukuran. Populasi dalam penelitian ini adalah siswa sekolah dasar di Kota Padang. Sampel dalam penelitian ini menggunakan metode purposive sampling dengan menggunakan siswa sekolah dasar putra putri usia 6-10 tahun. Teknik analisis data menggunakan uji normalitas, uji homogenitas dengan program SPSS 21. Hasil dalam penelitian ini berupa tes keterampilan bolabasket untuk anak usia dini. Tes keterampilan bolabasket yang disusun dinyatakan layak karena data normal dan homogen. Tes keterampilan bolabasket untuk anak usia dini dapat digunakan untuk pedoman guru PJOK dalam memberi nilai pelajaran bolabasket, serta dapat menjadi pedoman dalam pembibitan atlet bolabasket.
Development of Swimming Learning Models Through Adobe Flash Application Media in High Schools
Authors: Zulkifli Zulkifli , Henjilito Raffly , Yani Ahmad , Alficandra Alficandra , Makorohim M Fransazeli , Yudho Pijar Kuncoro , Zhuo Pua Ying
Published: June 2024

This study aims to produce a product in the form of a CS 6 Flash-Based Swimming Learning Model so that students can more easily understand swimming material and also make it easier for teachers to teach swimming. This study uses the Research and Development method. The steps in this research were: field needs analysis, compiling products, validating media and material experts, small-scale trials, second stage validation, large-scale trials, and the final product. The subjects of this study were students of class XI SMA Islam Az-Zahrah Palembang. Data was collected using a questionnaire for both experts and subjects. The results of this study are in the form of swimming learning models for teachers. Material experts state that this product is included in the good category (84.6%). Application experts stated that this product was included in the good/proper category with a percentage of 90.62% while for the small group and field assessment were 87.5% and 90.90%, respectively. It can be concluded that the development of this application can be used as a reference for teachers in the process of learning swimming material and the findings in this study are the results of applying swimming material to high school students from class XI.
Development of Basic Pencak Silat Techniques for High School Students
Authors: Wiguno Lokananta Teguh Hari , Kurniawan Ari Wibowo , Wahyudi Heri , Puspitasari Dianti Fera , Salamuddin Norlena
Published: June 2024

Pencak silat is one of popular martial art originated from Indonesia that is learnt by students from various level.  The learning process of pencak silat requires innovative media to help students learn it effectively. This study aims to develop an application-based learning media as a suitable solution to overcome problems related to PSHT martial arts learning material for the Persaudaraan Setia Hati Terate (PSHT) club at high schools. This study employed a research and development (R&D) methodology. The participants were 17 pencak silat student-athletes from the PSHT club or extracurricular program. Observations and interviews were conducted to collect the data. This research completed three expert validations, which include evaluations by coaching experts with an average score of 83.0%, PSHT material experts with an average score of 83.25%, and media experts with an average score of 97.5%. The overall product trial involved 17 student-athletes and was split into two phases: a small group trial with 5 participants, which achieved an 84.58% success rate, and a large group trial with 12 participants, which yielded an 80.90% success rate. Based on these results, the learning media for basic pencak silat techniques for PSHT student-athletes met valid standards and may be used without revision.
Cultivating Entrepreneurial Skills in Organic Farming with Design Thinking and Community-Based Education
Authors: Meekaew Nattapon , Chamaratana Thanapauge
Published: June 2024

Traditional agricultural training programs often fall short in cultivating the comprehensive entrepreneurial skill set necessary for navigating the challenges of modern organic farming. Moreover, the potential synergies between community-based learning approaches and design thinking principles in agricultural education are yet to be fully explored. This study investigates the impact of a training approach integrating community-based learning and design thinking to enhance entrepreneurship competencies among organic farmers in Khon Kaen province, Thailand. Using a quasi-experimental design involving sixty participants, the study employs pre- and post-training assessments to evaluate changes in entrepreneurship competencies, including innovation, risk management, business planning, and financial literacy. Preliminary findings indicate significant improvements in all competency areas post-training, highlighting the potential of combining the two approaches in agricultural education. This research contributes to the broader goals of sustainable agriculture and rural development in Thailand, offering insights for educators, policymakers, and practitioners aiming to empower the organic farming community.
Improving industry system for compliance assessment of welding consumables in reliance on ensuring technological independence
Authors: Аралов Олег Васильевич , Вьюнов Сергей Иванович , Ишбулатов Тимур Рамилевич
Published: June 2024

В условиях санкционных ограничений остро встает вопрос обеспечения российского рынка сварочных материалов, применяемых на опасных производственных объектах, включая магистральные трубопроводы, продукцией отечественного производства, а также расширения взаимодействия с производителями из стран, поддерживающих партнерские отношения с Россией. В этой связи система оценки соответствия сварочных материалов должна, с одной стороны, обеспечивать требуемое качество данного вида продукции, с другой – стимулировать привлечение добросовестных производителей. Целью настоящей статьи является анализ системы соответствия сварочных материалов, применяемых на объектах магистральных трубопроводов ПАО «Транснефть», с учетом решения задач по импортозамещению и обеспечению требуемого качества продукции в условиях переформатирования рынка. Авторами выполнен анализ производства сварочных материалов в России, проанализированы основные проблемные вопросы, связанные с оценкой соответствия и повышением качества данного вида продукции.

In the current conditions of sanction restrictions, there is an urgent problem of providing the Russian market of welding consumables used at hazardous production facilities, including main pipelines, with domestic products, as well as expanding the cooperation with manufacturers from countries that maintain partnerships with Russia. In this context, a compliance assessment system for welding consumables should, one the one hand, ensure the required quality of this type of products and, on the other hand, promote the attraction of bona fide manufacturers into the industry. The purpose of this paper is to analyze the compliance assessment system for welding consumables used at the main pipeline facilities of Transneft, taking into account the need to solve import substitution problems and to ensure the required product quality under the market reformatting conditions. The authors analyzed the production of welding consumables in Russia, studied the key problematic issues related to compliance assessment and improving the quality of this type of product.
Scientific opinion on the tolerable upper intake level for preformed vitamin A and β‐carotene
Authors:   EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck Dominique , Bohn Torsten , Castenmiller Jacqueline , de Henauw Stefaan , Hirsch‐Ernst Karen‐Ildico , Knutsen Helle Katrine , Maciuk Alexandre , Mangelsdorf Inge , McArdle Harry J. , Pentieva Kristina , Siani Alfonso , Thies Frank , Tsabouri Sophia , Vinceti Marco , Lietz Georg , Passeri Giovanni , Craciun Ionut , Fabiani Lucia , Horvath Zsuzsanna , Valtueña Martínez Silvia , Naska Androniki
Published: June 2024

Abstract
Following two requests from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the revision of the tolerable upper intake level (UL) for preformed vitamin A and β‐carotene. Systematic reviews of the literature were conducted for priority adverse health effects of excess vitamin A intake, namely teratogenicity, hepatotoxicity and endpoints related to bone health. Available data did not allow to address whether β‐carotene could potentiate preformed vitamin A toxicity. Teratogenicity was selected as the critical effect on which to base the UL for preformed vitamin A. The Panel proposes to retain the UL for preformed vitamin A of 3000 μg RE/day for adults. This UL applies to men and women, including women of child‐bearing age, pregnant and lactating women and post‐menopausal women. This value was scaled down to other population groups using allometric scaling (body weight0.75), leading to ULs between 600 μg RE/day (infants 4–11 months) and 2600 μg RE/day (adolescents 15–17 years). Based on available intake data, European populations are unlikely to exceed the UL for preformed vitamin A if consumption of liver, offal and products thereof is limited to once per month or less. Women who are planning to become pregnant or who are pregnant are advised not to consume liver products. Lung cancer risk was selected as the critical effect of excess supplemental β‐carotene. The available data were not sufficient and suitable to characterise a dose–response relationship and identify a reference point; therefore, no UL could be established. There is no indication that β‐carotene intake from the background diet is associated with adverse health effects. Smokers should avoid consuming food supplements containing β‐carotene. The use of supplemental β‐carotene by the general population should be limited to the purpose of meeting vitamin A requirements.
WEB-SERVICES FOR MICRORNA TARGET PREDICTION USING NEURAL NETWORKS
Authors: Aristarkhov M. , Dergilev A. , Potapova A. , Ivanov-Rostovtsev P. , Orlov Yuriy
Published: June 2024

The pursuit of microRNA target genes necessitates the creation of novel software and web services. MicroRNAs, abbreviated as short non-coding RNA molecules, hold a pivotal role in metabolic regulation, plant responses to environmental stress, and gene expression. Gaining insights into microRNA functions and investigating their target genes can advance drug development and address biotechnological challenges. However, the study and identification of microRNA targets within the genome present technical obstacles. MicroRNA molecules may not exhibit complete complementarity with their mRNA targets. These molecules either contribute to mRNA degradation or inhibit translation, and this process can transpire without full target complementarity. Consequently, the delineation of targets solely based on the principle of complementarity lacks unequivocal clarity. Moreover, a single microRNA molecule can correspond to multiple target genes simultaneously. The solution entails harnessing substantial datasets, employing machine learning techniques, and leveraging neural networks. In bioinformatics, neural networks serve a variety of functions, encompassing the analysis of biomedical data, diagnostics, prediction, classification, and nucleotide sequence segmentation. The pursuit and anticipation of microRNA targets through machine learning methods are currently undergoing vigorous development. A comparative assessment of contemporary neural networks for this task has been executed. A neural network-driven web service for microRNA prediction has been created. The server aspect of the service was developed using the Python programming language and the Flask library. The Mitar neural network, founded on deep learning, was employed. This network demonstrates heightened precision in predicting microRNA targets. We deliberate on the applications of miRNA prediction in gene expression analysis. Sustained research efforts are imperative to enhance the efficiency and broaden the capabilities of the developed computer system.
SIMULATION AND COMPUTER STUDY OF THE CHIRAL PROPERTIES OF PEPTIDE NANOTUBES BASED ON DILEUCINE
Authors: Bystrov V. , Filippov S. , Likhachev I. , Ledeneva O. , Belova E.
Published: June 2024

The paper presents calculations of the dipole, polar, and electronic properties of helical nanostructures based on dileucine (LL) of different chirality (L, D) using the AM1, PM3 methods from the HyperChem software package. It has been shown that the physical properties of dileucine-based nanotubes are close to those of diphenylalanine nanotubes (FF PNT). For nanostructures based on dileucine of left chirality L-LL, the existing experimental data make it possible to isolate from crystallographic structures molecular nanostructures of helical nanotubes that have right chirality D, which corresponds to the law of chirality change upon transition to the next level of self-organization. Model helical structures of nanotubes based on dileucine of right chirality D-LL were also constructed, for which there are no experimental data. Calculations of chirality by the method of mixed vector-scalar product of dipole moments of dipeptides showed that the law of changing the type of chirality is also valid for model helical nanotubes based on the D-LL. These results can be the basis for the synthesis of new experimental nanostructures based on right-handed dipeptides.
Monitoring Study of The Seagrass Ecosystem in Panrangluhu Beach Marine Water, Bulukumba, South Sulawesi
Authors: Supardi Wahyu , Pradana Andi Rizki Adi
Published: June 2024

The lamu meadow ecosystem is spread across Panrangluhu Beach, Bulukumba Regency. This research aims to identify seagrass types, density levels and seagrass cover in the Marine Waters of Panrangluhu Beach, Bulukumba Regency. The method used is a survey method by directly observing the condition of the seagrass ecosystem. Observations of seagrass beds used quadrant transects measuring 50 x 50 cm, along a 50 meter transect line with three transect lines. The research results obtained in the sea waters of Panrangluhu Beach were E. acroides at 81.75 stands/m2, T. hemprichii seagrass at 31.5 stands/m2, and S. isotifolium seagrass had a density value of 28.5 stands/m2. The seagrass density condition is classified as dense density, with dense seagrass cover conditions. The quality of the marine water environment at Panrangluhu Beach still supports seagrass life.
ANÁLISE DO NÚMERO DE INTERNAÇÕES POR EPISÓDIOS DE DEPRESSÃO NO ANO DE 2022
Authors: Ribeiro Everson Barrozo
Published: June 2024

Este estudo investigou as internações por depressão no Brasil em 2022, evidenciando uma alta incidência entre adultos jovens e uma predominância significativa entre as mulheres. Dos 32.237 casos regis
A Cartomante
Authors: Assis Machado de
Published: June 2024

Versão bilíngue Português/Libras para download no computador.

Este material foi feito originalmente para CD-ROM.

Como agora a maioria dos computadores não possuem mais leitores para este tipo de arquivo, estamos disponibilizando desta maneira devido à alta procura e a atualidade do conteúdo que se encontra acessível para o aprendizado de todas as idades.
HİVE VE ÜRGENÇ OĞUZ AĞIZLARINDA SÖZLÜKSELLEŞMİŞ YAPILAR
Authors: Cengiz Mustafa
Published: June 2024

Gelişmiş bir söz yapımı sistemine sahip olan Türk dilinde söz teşkilleri yalnızca eklerle değil, sözlük birimlerin işlenmiş biçimleriyle de yapılmaktadır. Bu sözlük birimler, anlamı tamamlayıcı unsurlar olabileceği gibi yardımcı fiil konumunda da olabilirler. Bunlar, ses düşmesi, ses benzeşmesi gibi birtakım ses bilgisel süreçler neticesinde işlenerek sözlük birim olma özelliğini kaybedip söz yapımında etkin kullanılan unsurlar durumuna gelebilmektedir.
Sözlükselleşme, dildeki unsurların türlü sebeplere bağlı olarak sözlüğe girmiş olmasını ifade etmektedir. Bu durum, çeşitli yollarla gerçekleşmektedir. Türk dilinin bazı lehçe ve ağızlarında görülebilen bu dil olgusu, Harezm’in Hive ve Ürgenç Oğuz ağızlarında da görülmektedir. Tespit edilebildiği kadarıyla sözlükselleşme süreci bu ağızlarda görevli sözcüklerin gramerleşme sonucu esas unsurla kaynaşması, yardımcı unsurların tabanlaşma yoluyla esas unsurla birleşmesi ve -(X)p zarf-fiil ekiyle gerçekleşmektedir. Tabanlaşma, al- esas fiilinden sonra kullanılan yardımcı unsurlarla et- yardımcı fiilinin, çeşitli ses bilgisel süreçler sonucu esas unsura dahil olmasıyla gerçekleşmektedir. Buna ek olarak bu ağızlarda bilen ve +din (< dey) edatları da sözlükselleşme sürecinde etkin olan görevli sözcüklerdir.
Bu çalışmada, tarihî ve çağdaş Oğuz değişkelerinde çeşitli şekillerde ele alınan sözlükselleşmiş yapıların Harezm’de konuşulan Hive ve Ürgenç Oğuz ağızlarında ne şekilde görüldüğü incelenmiştir.
Assessment of bacteria isolated from root nodules and rhizosphere of Vicia faba L.
Authors: Ghazala Shaheen  , Anita Tudu  , Vinay Oraon  , Latika Sharan
Published: June 2024

In this present study bacteria were isolated from the root nodules and rhizosphere of Vicia faba L. A total of 23 isolates were obtained which were studied morphologically. All isolates were identified on the basis of biochemical tests performed. The isolates obtained in this study can be used to decrease the need of chemical fertilizers and helpful in the production of biofertilizers.
A review: Polyherbal hair dye
Authors: Shital S Patil  , Kaveri Kiran Korde  , Prashant Dadaji Jadhav  , Shraddha Ashokrao Gawali  , Sakshi Bapusaheb Gaikwad  , Sarthak pawar
Published: June 2024

The composition of natural hair dye consisting of amla , henna , tea powder , beet root , clove powder,meethi seed powder, curry leaves powder are blended with lemon peel powder. Conventional hair coloring techniques use chemicals , which can have unfavorable side effects such as skin discoloration ,inflammation , hair breakage, and cancer. The goal of the current study used to investigate the formulation of those plants using variousorder to improve the quality and effectiveness of the colorant activity. Graying hair is a normal occurrence linked to aging and regular use of synthetic shampoos, which is promote the use of synthetic colors due to the rise in the use of dangerous chemicals during the manufacturing process. We preferred using polyherbal hair color for that reason.
Impact of COVID-19 on sovereign risk of emerging markets and developing Economies (EMDES)
Authors: Amuzu Ferdinand  , Kpodo Julius  , Sosu Korblah Patrick
Published: June 2024

This paper examines the impact COVID-19 has on the sovereign risk of emerging and developing markets and developing economies (EMDES) in ten selected West African countries. The study revealed that the daily documented cases and credit default swap (CDS) spread had an inverse relationship. This points to the fact that governments are likely to default because the available resources will be spent on catering to patients, which would increase their tendency to default. An OLS model was used to estimate the variables; this revealed that there is a higher CDS spread among emerging economies and markets. There exists a positive correlation between the explanatory variable and the explained variable, and this is an indication that the higher the border closure restrictions, the more COVID-19 is controlled, which results in a higher CDS spread among emerging economies and markets. The result concludes that the prevalence of this in these emerging and developing markets and developing economies reduces productivity, hence increasing the danger of default.
Understanding the impact of climate change on human health: A cross-sectional study in Danao City, Cebu, Philippines
Authors: Delfa G. Castilla  , Jhean Marian P. Gutang  , Nelvie Mae C. Pareja  , Rhea Fatima E. Peñas  , Shekina Leigh M. Petersen
Published: June 2024

This cross-sectional study in Danao City investigated the impact of climate change on human health, emphasizing the urgent need to address the health risks associated with rising temperatures and shifting weather patterns. The research aimed to establish a local understanding of how climate-related factors influence human health outcomes in the city. Findings revealed a high level of awareness among residents regarding the health risks linked to climate change, highlighting the importance of proactive measures to mitigate adverse effects. Recommendations include community education and awareness programs, climate resilience planning, healthcare capacity building, and ongoing research and monitoring efforts. By following these recommendations, Danao City can enhance its resilience to climate-related health challenges and protect the well-being of its population. This study contributes valuable insights to the intersection of climate change and human health at the local level, emphasizing the importance of specific actions to address health risks in vulnerable areas like Danao City. These actions are essential for building a healthier and more resilient community in the face of climate change impacts.
SINDROMA NEFROTIK RELAPS DENGAN ANEMIA PADA ANAK
Authors: Firsiyanti Aty , Nabiila Alyaa , Millenia Hava Ayu
Published: June 2024

Introduction: Nephrotic syndrome is a kidney disease characterized by edema, hypoalbumin, hyperlipidemia, and massive proteinuria. The prevalence in children ranges from 2-7 cases per 100,000 children under 18 years of age and most experience relapse. The prognosis for nephrotic syndrome in which it relapses will increase the risk of other complications.
Case report: A 4-year-old boy was diagnosed with nephrotic syndrome characterized by anasarca edema, hypoalbumin, hypercholesterolemia, and massive proteinuria. The patient was included in the relapsed nephrotic syndrome category because he had previously been diagnosed with nephrotic syndrome and had experienced remission. Currently, the therapy that has been given consists of bed rest, fluid restriction, administration of the diuretic furosemide and administration of the oral steroid prednisone again. In addition, the patient experienced anemia due to complications from nephrotic syndrome and a PRC transfusion was planned.
Discussion: Nephrotic syndrome is a kidney disease that often occurs in children. The prevalence is 15 times more common in children than adults. As many as 60-70% will experience a relapse. Relapsing nephrotic syndrome requires longer duration of corticosteroid therapy. Anemia is one of the complications in relapsing nephrotic syndrome.
SOCIAL RESPONSE OF KALIPEPE VILLAGE COMMUNITY IN YOSOWILANGUN SUB-DISTRICT IN THE IMPLEMENTATION OF PMK NUMBER 222/PMK.07/2020 ON VILLAGE FUND MANAGEMENT
Authors: Zuhri Saefudin , Supranoto Supranoto , Sisbintari Ika
Published: June 2024

The present study is to identify and analyze the social dynamics of the Kalipepe Village community in Yosowilangun Subdistrict in the implementation of PMK Number 222 / PMK.07 / 2020 regarding Village Fund Management. This study employs a descriptive research method with a qualitative approach. Based on the results, it was found that the community's social response did not meet one of the eight dimensions or criteria as seen from Lassawell's grand theory. These dimensions include sender, encoding, message, media, decoding, response, feedback, and noise. Specifically, the response dimension was found to be either inappropriate or not fully met. To enhance the community's social response, it is essential for the village government to prioritize transparency in both communication and mechanisms in the field. This approach will help prevent potential issues that could undermine equity and justice.
THE ROLE OF COOPERATION AND SMEs DEPARTMENT IN EFFORTS TO DEVELOP MSME PRODUCTS THROUGH THE “UMKM JUARA” PROGRAM IN SUKABUMI CITY
Authors: Fithriati Nenden Tari , Sampurna Rizki Hegia , Amirulloh M. Rijal
Published: June 2024

Micro, Small and Medium Enterprises are an important sector and have a large contribution in realizing regional economic development. In this case, it contributes 60 percent to GDP and is able to absorb labor up to 97.22 percent. Therefore, the West Java Provincial government created a program "UMKM Juara" to empower MSMEs. The purpose of this study is to find out how the role of the Cooperative and SMEs Office in efforts to develop MSME products through the "UMKM Juara" program in Sukabumi City. Researchers used the theory of Gede Diva, 2009 regarding the role of government as a facilitator, regulator, and catalyst. The results showed that the local government has done its job well in terms of facilitators, regulators and catalysts, however, there are still shortcomings in terms of MSME participant targets that have not been achieved and the lack of budget for the program that will be implemented.
POLICY IMPLEMTATION “LONTONG KUPANG” ONLINE AND INTEGRATED SERVICE ONE GATE SYSTEM
Authors: Ajiputra Rendy Fadila , Handoko V. Rudy
Published: June 2024

Lontong Kupang (Online and Integrated Services Through One Gate System Between Disdukcapil Surabaya, Surabaya Religious Court and Ministry of Religion Surabaya). The purpose of this research is to analyze the successful implementation of the Lontong Kupang program based on the Theory of Program Implementation Success according to George Edward III which consists of Communication, Disposition, Resources and Bureaucracy Structure. The method used in this study is descriptive qualitative with observation and interview data collection. The research results show that the Lontong Kupang Program has been successful and the implementation is good. However, in its implementation there are still several obstacles that hinder the implementation of the program. The inhibiting factors found in this research are the lack of budget availability for program implementation, and the lack of outreach to the community regarding the Lontong Kupang service program which results in many people not understanding the requirements or documents that must be brought when registering.