bluuebunny/crossref_metadata_2025 huggingface dataset:
Preparation and characterization of drug-loaded, electrospun nanofiber mats formulated with zein or zein-based mixtures for wound healing applications.
Authors: Aljamal Salah , Sotari Shrouq , Tarawneh Ola , Al-Hashimi Nabil , Hamed Saja , Al-Hussein Mahmoud , AlKhatib Hatim S.
Published: July 2023

Electrospun zein mats are known to have poor mechanical and water uptake properties limiting their usefulness as wound dressings.

In this study, the effects of the solvent system used, the incorporation of the polymeric additives; polyethylene glycol 20000 (PEG20K) and polyvinylpyrrolidone K30 (PVPK30); and the crosslinking agent Tannic Acid (TA) on the mechanical and water uptake characteristics of zein – based nanofiber mats were investigated.

The incorporation of either PEG20K or PVPK30 resulted in an improvement in water vapor sorption and a reduction in water contact-angle of the nanofiber mats. In addition, the incorporation of PEG20K and PVPK30 reduced the ultimate tensile strength, and Young’s modulus while increasing the percent elongation of the nanofiber mats. The use of tannic acid as a crosslinking agent led to an increase in the water vapor sorption, ultimate tensile strength, and Young’s modulus of the nanofiber mats.

Mats with smaller average fiber diameter, greater ultimate tensile strength, higher Young's modulus, and greater water vapor sorption were obtained when using 80% (v/v) aqueous ethanol as a solvent system during the preparation of the nanofiber mats when compared to those produced using 60% (v/v) aqueous ethanol. In addition, using solutions with lower zein concentration resulted in mats with lower average fiber diameter, lower ultimate tensile strength and Young’s modulus, and higher percent elongation.

Selected formulations were loaded with tetracycline hydrochloride and drug release was evaluated in bulk liquid and using Franz diffusion cells. The use of Franz diffusion cells allowed the discrimination between formulation performance as a function of composition and water uptake properties. Drug release from nanofiber mats was also confirmed by observing the formation of an inhibition zone in cultures of E. coli and S. aureus using the agar diffusion assay.

Improved performance of zein nanofiber mats was achieved using polymeric modifiers and crosslinking with tannic acid improving their suitability for wound dressing applications.
Preparation, in vitro and in vivo evaluation of solid-in-oil dispersion-based formulation the anti-glaucoma drug, timolol maleate
Authors: Barakat Noor , Jaber Mai , AlKhatib Hatim S.
Published: July 2023

Lowering Intraocular pressure (IOP) is a main therapeutic objective in glaucoma patients because IOP is an important risk factor for glaucoma progression. The objective of this work was to formulate and evaluate, in vitro and in vivo, a stable and effective Solid in Oil (S/O) topical formulation of the antiglaucoma drug, timolol maleate (TM). S/O dispersions were prepared by emulsification of aqueous TM solutions in cyclohexane using different amount of the span 85 then lyophilizing the emulsion to produce TM – Span 85 complexes. The complexes were then dispersed in castor oil using tip sonicator to produce S/O nanodispersions. S/O nanodispersions were evaluated in terms of particle size, polydispersity index, encapsulation efficiency, morphology, physical stability, as well as transcorneal permeation and accumulation of TM. In addition, the in vivo tolerability and efficacy of the prepared formulation in lowering intraocular pressure were evaluated in rabbits.

Spherical nanoparticles of TM with a particle size of about 134-155 nm were successfully prepared and found to be physically stable. The encapsulation efficiency was high and was found to be dependent on the level of Span 85 used.

In comparison to TM solution, S/O nanodispersion enhanced TM permeation and decreased accumulation in transcorneal diffusion studies. In addition, application TM S/O nanodispersion onto rabbit eyes resulted in a significant reduction in IOP in comparison to TM aqueous solution.
Video-based teach-to-goal intervention on inhaler technique on adults with asthma and COPD: a randomized controlled trial
Authors: Al-Kharouf Mohammad , Abdeljalil Mariam , Obeidat Nathir , Al Oweidat Khaled , Awwad Oriana
Published: July 2023

The incorrect use of inhalers is highly associated with poor patient outcomes. This randomized controlled trial investigated the impact of a novel video-based teach-to-goal (TTG) intervention on the following outcomes; mastery of inhaler technique, disease control, medication adherence, and disease-related QoL over time among patients with asthma and COPD.

After baseline assessment, participants received either a verbal (control group) or a video-based (intervention group) TTG strategy and were assessed after three months for the impact of the intervention on the intended outcomes. At baseline, intervention (n=51) and control (n=52) groups had comparable characteristics. At follow-up, inhaler technique and medication adherence improved among the intervention group compared to control group ((93.4% vs 67%) and (88.2% to 61.5%), respectively (p<0.05)) as well as to baseline ((93.4% to 49.5%) and (88.2% to 66.7%), respectively (p<0.05)). Similarly, disease control was also ameliorated among the intervention group compared to baseline (35.3% to 54.9%) (p<0.05). QoL scores improved significantly among asthma patients (intervention group) at follow-up in comparison to baseline. Better scores were also observed for COPD patients compared to controls, (p<0.05).

Interventions using video-based TTG education are effective in enhancing and retaining the inhaler technique over time, with a positive impact on disease outcomes among patients with asthma and COPD.
Aspirin Effect on Tobacco Smoke Withdrawal-Induced Anxiety In Female Rats
Authors: Alzaghari Lujain F. , Hammad Alaa M.
Published: July 2023

Chronic exposure to cigarette smoke produces neuroinflammation and long-term changes in neurotransmitter systems, especially glutamatergic systems. We examined the effects of cigarette smoke on astroglial glutamate transporters as well as NF-κB expression in mesocorticolimbic brain regions including the prefrontal cortex (PFC) and the nucleus accumbens (NAc). The behavioral consequences of cigarette smoke exposure on withdrawal-induced anxiety-like behavior were assessed using open field (OF) and light/dark (LD) tests. Sprague-Dawley rats were randomly assigned to 5 experimental groups: a control group exposed only to standard room air, a cigarette smoke exposed group treated with saline vehicle, two cigarette smoke exposed groups treated with aspirin (15mg/kg and 30mg/kg, respectively). Lastly, a group treated only with aspirin (30 mg/kg). Cigarette smoke exposure was performed for 2hr/day, 5days/week, for 31days. Behavioral tests were conducted weekly, 24hrs after cigarette smoke exposure, during acute withdrawal. At the end of week 4, rats were given either saline or aspirin 45 min before cigarette exposure for 11 days. Cigarette smoke increased withdrawal-induced anxiety, and 30 mg/kg aspirin attenuated this effect. Cigarette smoke exposure increased the relative mRNA and the protein level for nuclear factor ĸB (NFĸB) in the PFC and the NAc, and aspirin treatment reversed this effect. In addition, cigarette smoke decreased the relative mRNA and the protein levels of glutamate transporter 1 (GLT-1) and the cystine-glutamate transporter (xCT) in the PFC and the NAc, while aspirin treatment normalized their expression. Thus, cigarette smoke caused neuroinflammation, alterations in relative mRNA glutamate transporter expression, and increased anxiety-like behavior, and these effects were attenuated by aspirin treatment.
ENCAPSULATION OF PLANT GROWTH-PROMOTING BACTERIA USING VERMICAST AND COW MANURE FOR BASIL PLANT (Ocimum basilicum) GROWTH AND PLANT NUTRIENT ENHANCEMENT
Authors: Badarudin Amzar Fahmi , Othman Nur Maizatul Idayu , Sulaiman Nazhatul Syahirah , Shaharudin Alif Farhan , Abu Sari Norazlina , Kassim Nur Qursyna Boll , Kamarulzaman Nur Badriyah
Published: July 2023

Enterobacter sp. bacteria was successfully selected from UITM Pathology lab collection with the specific characteristic which is IAA production, and phosphate solubilization, nitrogen fixation test, siderophore production, and cellulose degradation. The selection of Enterobacter sp. was referred from the potential amount of IAA production that suitable for basil plants that rich with chemical compositions. The bacteria was entrapped as a potential of plant growth-promoting bacteria that consisted with sodium alginate solution, vermicast and cow manure. The bacteria population for all encapsulation of biofertilizer is range from 10^8-10^14.Vermicast and cow manure is act as carriers for the bacteria that has potential in a long lifespan. Three treatments which are encapsulated of vermicast, encapsulated of vermicast and cow manure, and encapsulated of vermicast and cow manure with PGPB were observed for the plant growth such as plant height (shoot length),number of leaves and plant nutrient enhancement of (Ocimum basilicum). This study observed that the treated plants with encapsulated PGPR with vermicast and cow manure showed the positive impacts on the growth and plant nutrient compared to control plants. Encapsulation technique is used as the method for entrap the bacteria with the carrier.
EFFECT OF ETHANOLIC SOLVENT POLARITY ON THE PHYSIOCHEMICAL PROPERTIES OF Graptophyllum Pictum. L
Authors: Ismail Faikah , Maddiah Nurul Izzah
Published: July 2023

This study aims to compare the total phenolic content (TPC) and total flavonoid content (TFC) of Graptophyllum pictum (L.) Griff or G. pictum (L). The leaves of G. pictum (L) were dried under 50ºC in a drying oven for 24 hours and then were ground by using a grinder until a uniform fine powder was obtained. Sample extraction was done by maceration technique for 7 days with three different ethanolic percentages, 50%, 70%, and 80% to be then concentrated with a rotary evaporator under 45 ºC. Qualitative analysis of G. pictum (L) extracts was done by two tests, the Ferric Chloride test for phenolics and the Shinoda test for flavonoids. Ethanol was used as the negative control while gallic acid as the positive control for TPC and quercetin for TFC. G. pictum (L) extracts were found to have the presence of both phenolics and the flavonoids compound by the formation of bluish-black colour for the ferric chloride test and the formation of pink scarlet colour for the Shinoda test. Standard calibration curves of gallic acid and quercetin were prepared. The quantitative analysis was carried out with a phytochemical screening of G. pictum (L) extracts using a standard procedure revealing the absorbance value of TPC and TFC. Folin Ciocalteu’s method was done to identify the absorbance of TPC while the aluminum chloride method was done for determining the absorbance of TFC through a UV-VIS spectrophotometer. 50% ethanolic solvent yielded the highest TPC and TFC (84.24 ± 0.09 mg GAE/g and 19.824 ± 0.08 mg QE/g respectively). Statistical analysis was done for all results obtained through ANOVA. There is no significant difference in absorbance TPC and TFC value between the ethanolic percentages. Despite that, in conclusion, 50% ethanolic solvent came out the best in extracting the phytochemicals. G. pictum (L) has the potential to be a useful resource in the development of a drug for the treatment of PCOS.
BUILDING MAINTENANCE: DETERMINE OF FUNGAL GROWTH ON OFFICE BUILDING USING GEOGRAPHIC INFORMATION SYSTEM (GIS)
Authors: Abdul Wahab Suriani Ngah , Mokhtar Munirah Radin , Mohammad Ali Irwan , Hamid Md Yusof
Published: July 2023

This paper presents the preliminary concept using a Geographic Information System (GIS) to determine fungal growth in an office building, especially in the UiTM Perak branch. As we all know, various viruses and bacteria exist in our environment. The quality of the air affects our health throughout the day. If the quality of the air is polluted, then it is very likely that we will get sick and vice versa. In this research the methodology applied is using geocoding in GIS applications. Analysis using a GIS is used to find the contributing factors to the reproduction of fungi on the walls of the buildings being studied. Based on the obtained results it can be concluded that the proposed methodology creates a convenient, efficient, and inexpensive tool for massive inspection of building resources in large areas. There are several processes to investigate the effects of buildings factors contributing to fungal growth cases such as the creation of rooms database, temperature derivation process and lastly data analysis using the attributes spatial table. Finally, the location of the rooms where the fungal growth is determined is shown by the map results.
EDUCATION CHALLENGES IN SABAH BEFORE 1963
Authors: Sharif Adam Sharifah Darmia
Published: July 2023

Sabah is one of the states in the Federation of Malaysia that is famous not only for the natural beauty of its flora and fauna but also for the uniqueness of its community which consists of dozens of ethnic groups. Based on history, education in Sabah has existed since the administration of the Sultanate of Brunei and the Sultanate of Sulu. While under the rule of the Sultanate of Brunei, the Muslim community who mostly lived in the coastal area of Sabah had an education based on the study of the Al-Quran. During that period, education was in an informal form focused on religious book reading activities carried out in prayer hall, mosques and lodges. Meanwhile for the non-Muslim community, education is also informal through guidance from parents, certain ceremonies or celebrations. When Sabah was under the administration of foreign powers, education in the state was heavily influenced by the policies of administrators such as the British North Borneo Chartered Company (SBBUB) and British colonialism. However, it is generally found that the education of the Sabah community is not taken seriously by the SBBU administrators nor the British colonial authorities. Therefore, the discussion will be focused on the challenges faced in the field of education in Sabah before 1963. The study of this paper uses a qualitative analysis approach and uses archival and library research methods by analyzing various primary and secondary sources such as Colonial Office Files, Statements Annuals, books and articles to obtain research information sources. This study will produce an analysis that can provide a clearer understanding of the historical background of the development of education in Sabah. Identification of the challenges faced will enable the planning of strategies that can further strengthen education in Sabah.
CONTROVERSIES IN THE ROLE OF WRITTEN CORRECTIVE FEEDBACK IN L2 WRITING
Authors: Abd Rahim Sabariah
Published: July 2023

Truscott has strongly opposed the use of written corrective feedback in second-language writing classes. According to Truscott, written corrective feedback generates pseudo-learning that has a significant impact on the L2 development of learners. In response, experts in Second Language Acquisition and Second Language Writing addressed his argument. This paper examines the debates surrounding the function of written corrective feedback in L2 writing.
ACCEPTANCE AND EFFECTIVENESS OF TASAWWUR ISLAM COURSE AMONG FOUNDATION STUDENTS AT UNIVERSITI MALAYSIA SABAH
Authors: Mokhtar Saifulazry , Thia Kasoma
Published: July 2023

The offer of basic studies at Universiti Malaysia Sabah (UMS) is the same as that offered at other local universities, namely to students who are graduates of Sijil Pelajaran Malaysia (SPM). In pursuing the foundation level at Universiti Malaysia Sabah, Muslim students need to follow the subject of Tasawwur Islam as one of the compulsory subjects. The subject of Tasawwur Islam is a continuation of the application of religious knowledge to Muslim students to provide added value to their lives. The question that arises here is does this Tasawwur Islam course have an encouraging impact on the lives of students? Therefore, this study was conducted to see the level of acceptance and effectiveness of Tasawwur Islam courses among students at UMS. This study uses quantitative methodologies based on questionnaires distributed through Google Form. There were 50 respondents among the students at UMS who had taken the time to participate in their views and perceptions on the level of acceptance and effectiveness of the Tasawwur Islam course at the foundation level. The results of the Tasawwur Islam course offering at the foundation level showed that 84% of the students can increase their knowledge especially in the ins and outs of Islam, 60% of students can apply the knowledge gained in everyday life and 42% of students can transform themselves into a better person than before. Overall, the offering of Tasawwur Islam courses at this fundamental level has a positive impact on the lives of students in the coming days.
INTERACTION BETWEEN SCHOOL ORGANIZATIONAL CLIMATE AND PASSION FOR TEACHING TOWARD TEACHERS’ PSYCHOLOGICAL WELL-BEING IN SEBERANG PERAI TENGAH, PULAU PINANG
Authors: Othaman NorHasyimah , Baba Rahim Norizan , Hilmi Mohd Faiz
Published: July 2023

Psychological well-being means the individual's ability to accept themselves and others in their environment as well as knowing their own potential in addition to developing their existing potential. Teachers are one of the important elements in pedagogy to produce quality education, especially in mastering 21st century learning skills. The imperfect psychological well-being of teachers can affect their quality of life. School organizational climate is a general concept that includes the environment experienced by educators and patterns their behavior especially in the school area. Based on Social Cognitive Theory (Bandura, 1986; 1997), this study investigates the interaction between the school's organizational climates on the psychological well-being of teachers in Seberang Perai Tengah, Penang in addition to Passion for Teaching used as a mediator between the two variables. To test the suggested hypothesis, data was collected through a questionnaire. The sample of this study consists of 196 teachers who teach in the Seberang Perai Tengah district, Penang who use the rules of thumbs by Roscoe et al. (1975) This study has found that the relationship between the School Organizational Climate and the psychological well-being of teachers is related, but the passion for teaching as a mediating variable used in this study does not show a relationship between the organizational climate and the psychological well-being of teachers. Based on the findings of the study, the methodology, theoretical and practical implications of the study were discussed. Recommendations for future research are also presented.
THE LEARNING OF WOMEN'S BLOOD IN THE SCIENCE SUBJECT OF THE SECONDARY SCHOOL STANDARD CURRICULUM (KSSM): A COMPARISON OF FIQH AND SCIENTIFIC PERSPECTIVES
Authors: Tengku Kasim Tengku Sarina Aini , Yaakob Siti Falihah , Mohd Razif Nor Fahimah
Published: July 2023

Muslim men and women are required to study the corpus of knowledge known as women's blood education, which includes the science of menstruation, childbirth, and istihadah, as well as the related laws. This is due to the fact that the knowledge of women's blood is one of the sub-discussions under the chapter on worship, which contains laws pertaining to the fundamentals of Islam, such as prayer, fasting, and Hajj. At the secondary education level, this topic is introduced to 13-year-old Form 1 students through Form 1 science classes that include a subtopic on the menstrual cycle. The content analysis revealed, however, that there is a significant difference between the menstrual cycle learning content included in the Standard Document for Curriculum and Assessment (DSKP) of Form 1 science subjects and the discussion of the menstrual cycle from the perspective of jurisprudence, which has implications from the standpoint of legal determination. Therefore, the purpose of this article is to compare the discussion of menstrual blood written in the Standard Document for Curriculum and Assessment DSKP of Science KSSM Form 1 in Malaysia with the discussion of menstruation from a jurisprudential perspective in order to provide students with a correct understanding and prevent the existence of misunderstandings in determining the status of menstrual blood and istihadah in their subsequent learning. This research employs the comparative method to analyse multiple documents pertaining to the disciplines of science and fiqh. Analysed documents included the Standard Document for Curriculum and Assessment DSKP for Science subjects in the Malaysian Secondary School Standard Curriculum (KSSM), the Malaysian KSSM Form 1 Science textbook, the Syafi'i school of law, articles, and scientific studies. According to the results of the analysis, there are three differences in the input about menstrual blood that is placed in the textbook of Science subjects Form 1 with the discussion of menstruation from the perspective of the law, namely the age of puberty, the age of menopause, and the menstrual cycle. The differences in the input of menstruation learning content necessitate a clear understanding and comprehension of this subject specifically in the subject of Islamic Education under the subtopic of worship. Therefore, cooperation from all parties, including instructors, the administration, and the government, is crucial so that all students can learn about women's blood in school, thereby enabling them to worship with greater assurance.
WHOLE BRAIN TEACHING STRATEGIES PROMOTE ACTIVE LEARNING STUDENTS YEAR FOUR IN SCIENCE SUBJECT
Authors: Sudin Nurul Hakimah , Abdullah Haslinah
Published: July 2023

Active learning is an important aspect of creating a fun and achieving learning outcomes, but it is quite difficult to create in science subjects if the approach used by teachers is less appropriate. This study is an action research conducted to improve active learning among primary school students using Whole Brain Teaching Strategies (WBTS) in Science subjects. The only three types of WBT strategies used are Class-Yes, Mirror-Words and Teach-Okay. This action research was conducted among 42 students of Year 4 at a primary school in Nilai, Negeri Sembilan. Data were collected through 2 methods, which are video recording and interviews with students and Science teacher. The results of the study found that Whole Brain Teaching Strategies (WBTS) has been able to increase students' active learning during the learning process as this strategy can develop cognitive remembering. Moreover, students understand what is taught by teachers in learning process through WBTS where it affects information retention in student's long term memory. Therefore, students show positive emotional development. In addition, it can create a meaningful cooperative learning with positive social interactions between peers when students are positively interdependent in the team. Each group member strives to complete group assignments and help weaker members so that the group success is experienced together thus strengthening intrinsic motivation among students. The use of WBTS has been able to be applied effectively in enhancing a meaningful learning process in the classroom that can give ideas to other teachers to apply in other subjects as well.
EXPLORING DIGITAL ASSESSMENT LITERACY IN MALAYSIAN ESL TERTIARY INSTITUTION INSTRUCTORS’ INNOVATIVE PEDAGOGY
Authors: Suyansah Ameera Irdena , Said Noraini , Jawing Esther
Published: July 2023

This conceptual paper aims to study the digital assessment literacy of ESL instructors in Malaysia. In education, assessment is one of the most crucial components in the teaching and learning process. Assessment allows the instructors to gather information of the students to determine the students’ knowledge and to make improvements based on the data collected. With the digitalisation in education, it has propelled the relevancy of digital assessment. Despite the increasing use of digital assessments in educational settings, many educators lack the necessary digital assessment literacy skills to effectively create, administer, and interpret these assessments. Therefore, this study aims to explore the digital assessment literacy of ESL instructors. This study will use semi-constructed interview and analysis of documents. The type of sampling employed in this study is purposive sampling towards 15 ESL instructors in Malaysian Universities. The data will be analysed using thematic analysis. The expected result from this study is that ESL instructors will have knowledge of digital assessment but have areas of improvement in doing digital assessment. The researchers acknowledge that knowing how to use digital assessment tool is not sufficient, and teachers need to remain aware of how these tools are successful or unsuccessful. It is hoped that the outcome of this research will help the teachers to be knowledgeable in how they understand, conduct, and interpret digital assessments
Crise do capital e a condição periférica
Authors: Canettieri Thiago
Published: July 2023

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30 anos da luta antimanicomial
Authors: Ignatowski Thiago Salles
Published: July 2023

A loucura esteve sempre intimamente relacionada à exclusão social e à violência. O “século das luzes” trouxe, ironicamente, o obscurantismo para o tratamento do louco, tornado mero objeto de estudo das ciências emergentes, segregado e violentado em instituições asilares-manicomiais. Esse tratamento dado à loucura, adotado como paradigma durante séculos, contribuiu para construir no imaginário popular uma compreensão da pessoa em sofrimento psíquico como um sujeito sem dignidade. Nesse cenário, a Luta Antimanicomial representa uma insurgência, contra essa visão segregacionista que reproduz a violência simbólica impingida a formas de vida consideradas “anormais”. Seu desafio vai além da modificação de leis e implica, sobretudo, a desconstrução de uma barreira discursiva que impede o reconhecimento do “louco” como pessoa e o respeito a sua dignidade.
controle da violência policial na democracia brasileira
Authors: Brito Tiago de Jesus
Published: July 2023

A proposta deste artigo é entender a atuação da Justiça Militar, em relação a casos de homicídio ocorridos no estado de Minas Gerais e que tem como suspeitos de sua prática policiais militares. O estudo parte do pressuposto da importância de se controlar a violência policial em um estado democrático, o que tem se demonstrado falho no Brasil que mesmo no regime democrático continuou vinculando as forças policiais às forças armadas, marcada por um sistema diferenciado de justiça no qual são submetidos seus membros na condição de militares. Como base empírica do estudo, serão analisados os processos penais militares, disponibilizados na cidade de Belo Horizonte, referentes a casos ocorridos nos últimos dez anos. A partir do escrutínio desta fonte de informação, pretendo problematizar os limites no controle da violência policial realizado pela Justiça Militar.
Expediente v. 2, n. 1, 2023 - Edição Especial SEMUCE
Authors: Rocha Luis , Andrade dos Santos Camila , Lima Marcio Soares
Published: July 2023

A revista [re]Design é uma publicação acadêmica-científica semestral do Núcleo de Design e Tecnologias da Informação e Comunicação, vinculado a Editora IFMA e ao Instituto Federal do Maranhão, e que tem como objetivo promover, apoiar e valorizar a ciência por meio da reflexão e do diálogo sobre os estudos ligados interdisciplinarmente ao campo da Arquitetura, Artes e do Design, possibilitando a democratização do acesso ao conhecimento tecnológico de forma construtiva e inclusiva. A revista [re]Design apoia-se em princípios de produção de editorial científica de qualidade, transparente e inclusiva para oferecer um conteúdo científico que alcance públicos diversos. A revista atua na divulgação de conteúdo no qual os autores mantêm os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a Licença Creative Commons Atribuição-Não Comercial 4.0 Internacional (CC BY NC 4.0), que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista. As opiniões e conteúdos nos resumos e textos completos publicados são de responsabilidade exclusiva de seus autores e não necessariamente refletem as opiniões dos membros da revista, bem como pela devida permissão para uso das ilustrações ou tabelas publicadas de outras fontes, são de exclusiva responsabilidade dos autores. Este periódico também não aceita e tampouco tolera artigos com conteúdos de caráter discriminatório, calunioso, e/ou difamatório e/ou que viole todo e qualquer tipo de direitos privados e/ou comerciais de terceiros.
Personal dignity as an object of criminal and legal protection
Authors: Rudenko A. A. , Makromenko V. D.
Published: July 2023

The article presents the problems of the personal dignity category as an object of criminal and legal protection. The authors, based on scientific methods, attempted to consider the right to personal dignity from the standpoint of a constitutional system, that requires comprehensive protection. The fact of anticipatory decriminalization of the acts provided for by Art. 129, 130, 297 of the Criminal Code of the Russian Federation (RF CC) is recognized. The possibilities of the Constitutional Court of the Russian Federation are presented. It is stated that the criminal and legal characteristic of the category of personal dignity, having a wide range of influence, extends to all spheres of life in Russia.
National system of judicial accounting of accounting of the Republic of Kazakhstan
Authors: Kuznetsov I. I. , Kuznetsova A. A.
Published: July 2023

The article provides an in-depth analysis of the current legislation of the Republic of Kazakhstan, examines certain provisions of the Constitution of the Republic of Kazakhstan, as well as a number of other normative legal acts. Along with it the features of realization of such principle of activity as economic development for the good of the people, fixed in article 2 of the acting Constitution of the Republic of Kazakhstan, are opened. The national system of accounting regulations of the Republic of Kazakhstan is defined as a driving force of improvement of its economy. The system, characterized by a certain structure and special hierarchy, is represented by the legal mechanism of accounting regulations with unified accounting requirements. The national system of accounting regulations reflects the specifics of interaction of normative legal acts on the basis of their belonging to one of the levels of the described system. In the process of research some features of the national system of accounting regulations of the Republic of Kazakhstan were revealed. Particular attention is paid to the legal and methodological bases of accounting in relation to the economic entity. The question of the role of the President of the Republic of Kazakhstan and the Ministry of Finance of the Republic of Kazakhstan in the formation of a national system of accounting regulations is highlighted.
O Conceito de Consequência Lógica e os Problemas do Pluralismo e do Anti-Excepcionalismo
Authors: Batista Neto Alberto Leopoldo
Published: July 2023

ResumoApresentam-se alguns conceitos fundamentais e posições representativas referentes a três debates correntesna filosofia da lógica, a saber aquele acerca da natureza da relação de consequência, o que versasobre o problema do pluralismo lógico (e sua alternativa fundamental, o monismo) e o que gira em tornoda chamada proposta anti-excepcionalista, que nega o caráter excepcional da lógica e a põe numa relaçãode continuidade essencial com as demais ciências, de modo a evidenciar pontos de conexão entre as trêsdiscussões mencionadas. Levanta-se, por fim, a questão da plausibilidade da posição, presentementeminoritária, de um anti-excepcionalismo pluralista, vinculando-a, por sua vez, à aceitação de algumavariedade de pluralismo científico.Palavras-chave: consequência lógica; pluralismo lógico; anti-excepcionalismo lógico.AbstractSome fundamental concepts are presented, along with the theses relative to three current debates in thephilosophy of logic, namely the one concerning the nature of the relation of logical consequence, the oneover the problem of logical pluralism (and its fundemental alternative, monism), and the one around theso-called anti-exceptionalist proposal, which denies logic’s exceptional character and puts it in a relationof essential continuity with the remaining sciences, so as to highlight the points of connection betweenthe three aforementioned discussions. The question is raised, finally, of the plausibility of the position,presently of small currency, of a pluralist anti-exceptionalism, which is associated, in its turn, to the acceptanceof some variety of scientific pluralism.
A Música na Dissertatio de Arte Combinatoria, de Leibniz
Authors: Fortes Fabrício
Published: July 2023

ResumoO artigo apresenta um estudo sobre as aplicações feitas por Leibniz de sua arte combinatória ao campomusical. Elucidamos inicialmente alguns conceitos fundamentais, bem como alguns procedimentos dacombinatória leibniziana, e mostramos os usos musicais sugeridos por Leibniz para esses procedimentos.Em seguida, discutimos o alcance geral da abordagem combinatória em música e concluímos que Leibnizantecipa, na Dissertatio, a introdução de procedimentos vinculados à música contemporânea.Palavras-Chave: Combinatória. Música. Pensamento Simbólico. Leibniz.Abstract.The paper presents a study on Leibniz’s applications of his combinatorial art to the musical field. First, weelucidate some fundamental concepts, and some procedures of Leibnizian combinatory, and we show themusical uses suggested by Leibniz for these procedures. Then, we discuss the general scope of the combinatorialapproach in music, and we conclude that Leibniz anticipates, in Dissertatio, the introduction ofsome procedures related to contemporary music.
Nietzsche: Crítica e Desprezo
Authors: Leite Thiago Ribeiro Magalhães
Published: July 2023

ResumoAlguns leitores de Nietzsche podem admitir certa dificuldade em reconhecer os limites entre a crítica, a genealogia e o filosofar com o martelo. Tais limites existem e podem ser delineados se buscarmos o elemento no qual cada uma dessas investidas atua. Este artigo procura elaborar a ideia de que a noção nietzschiana de crítica envolve o desprezo afirmativo, o riso e a zombaria. Ligada, portanto, a uma condição valorativa, a crítica é mais ofensiva, exigente e assumidamente tendenciosa do que se poderia conceber a partir da tradição kantiana.AbstractSome readers of Nietzsche may admit some difficulty in recognizing the boundaries between criticism, genealogy, and philosophizing with the hammer. However, such limits exist if one seek the element that produces each one. This article tries to elaborate the idea that the affirmative contempt, laughter, mockery, for Nietzsche, defines the critic. Related, therefore, to an evaluative (and physiological) condition, criticism is more virulent, offensive, demanding and biased than one might think from a Kantian tradition.
The Number of Things in the World and the Autonomy of Logic
Authors: Nakano Anderson
Published: July 2023

Em seu livro recente, Engelmann (2021) avançou uma leitura do Tractatus que, a seu ver, removeria as dificuldades presentes em outras leituras (em particular, nas leituras “metafísica” e “resoluta”). Neste artigo, ocupar-me-ei da crítica de Engelmann às leituras metafísicas do Tractatus. Tal crítica baseia-se na ideia de que essas leituras estão comprometidas com algumas necessidades de re, o que violaria a autonomia da lógica e a ideia Tractariana segundo a qual só há necessidade lógica. Analisarei o caso particular de uma suposta necessidade de re, a saber, a do número de objetos no mundo. Depois de descrever alguns aspectos positivos e alguns obstáculos à interpretação de Engelmann desse caso, sugerirei que Engelmann está inconscientemente atribuindo ao Tractatus uma concepção de lógica que Wittgenstein, por sua vez, criticamente atribuiu a Russell e a Ramsey e que, portanto, não pode ser a sua. Por fim, retornarei à motivação original para a interpretação de Engelmann, que é a de salvar a autonomia da lógica, mostrando de maneira breve como conciliar a autonomia da lógica com um número fixo de objetos.AbstractIn a recent book, Engelmann (2021) has put forward a reading of the Tractatus which he maintains would remove the difficulties presented in other readings, particularly the “metaphysical” and the “resolute” readings. In this paper, my concern will be with Engelmann’s criticism of the metaphysical readings of the Tractatus. This criticism is centered on the idea that such readings are committed to some de re necessities,which violates the autonomy of logic and the Tractarian idea that there is only logical necessity. I analyze the particular case of a supposed de re necessity, namely, the number of objects in the world. After describing some positive aspects and drawbacks of Engelmann’s interpretation of this case, I suggest that Engelmann is unconsciously attributing to the Tractatus a conception of logic that Wittgenstein in turncritically attributed to Russell and Ramsey; thus, this conception cannot be his own. Finally, I return to the original motivation for Engelmann’s interpretation, which is to save the autonomy of logic, and briefly show how to conciliate the autonomy of logic with a fixed number of objects.
O Logicismo de Frege e Russell e a Rejeição Tractariana de Classes: uma tentativa de elucidação de 6.031
Authors: Ferreira Rodrigo Sabadin
Published: July 2023

Wittgenstein afirma no Tractatus que a teoria das classes é supérflua na Matemática e que isso está relacionado ao fato de que a generalidade exigida pela Matemática não é “acidental” (TLP 6.031). O objetivo deste texto é elucidar essa afirmação chamando a atenção para o que, seguindo Gregory Landini, tomaremos como uma forma de Logicismo compartilhada por Frege e Russell. Esta forma de Logicismo tem dois princípios básicos, a saber: o uso de uma teoria lógica cujas variáveis estruturadas incorporam o que hoje chamamos de teoria dos tipos simples e a análise de atribuições numéricas em termos de afirmações sobre conceitos ou atributos que empregam conceitos de ordem superior exatamente análogos aos chamados quantificadores ‘numericamente definidos’. Argumentamos que é esse arcabouço teórico que Wittgenstein está rejeitando em 6.031 e não apenas o uso da Teoria dos Conjuntos na Matemática. Também é defendido que a noção de classe ainda tem um papel essencial a desempenhar no Tractatus.AbstractWittgenstein claims in the Tractatus that the theory of classes is superfluous in Mathematics and that this is related to the fact that the generality required by Mathematics is not “accidental” (TLP 6.031). My aim in this paper is to elucidate this claim by calling attention to what, following Gregory Landini, I refer to as a form of Logicism shared by Frege and Russell. This form of Logicism has two main tenets, namely:the use of a logical theory whose structured variables embody what we nowadays call the simple theory of types and the analysis of number ascriptions in terms of assertions about concepts or attributes which employ higher-order concepts exactly analogous to so-called ‘numerically definite’ quantifiers. It is argued that it is this shared theoretical framework that Wittgenstein is rejecting in 6.031 and not just the use of Set Theory in Mathematics. It is also argued that the notion of class still has an essential role to play in the Tractatus.
From Logic Towards the Mystical: the Appearance of Mysticism in Wittgenstein’s Writings
Authors: Lima Rodrigo César Castro
Published: July 2023

Meu objetivo aqui é o de abordar os escritos iniciais de Wittgenstein com base na tradição do misticismo filosófico. O benefício de minha leitura se deve ao fato de permitir uma certa clarificação no que tange a determinadas passagens obscuras, além de trazer à tona perspectivas inexploradas concernentes ao período inicial do autor; fase esta que, em minha opinião, ainda requer um nível de escrutínio adicional.Entendo que especialmente no caso do Tractatus, Wittgenstein não incida no místico por conta de uma limitação da perquirição lógico-linguística relacionada a determinadas regiões do conhecimento, pelo contrário. Irei sugerir que a aplicação da lógica ocorre com o propósito de estabelecer o escopo do místico. Portanto, o que proporei em seguida é a tentativa de desenvolvimento de uma “interpretação mística” emrelação aos escritos iniciais do autor.AbstractMy goal here is to approach Wittgenstein’s initial writings based on the tradition of philosophical mysticism. The benefit of my reading is that it will allow some clarification in regard to obscure passages and still unexplored perspectives concerning this initial period which, in my opinion, still require additional scrutiny. As I see it, especially when it comes to the Tractatus, Wittgenstein does not “arrive” at the mystical due to the failure of a logical-linguistic inquiry/analysis related to certain realms of knowledge, on the contrary. I will make a case for supposing that the application of logic occurs with the purpose of establishing the scope of the mystical. Therefore, what I propose here is an attempt to develop a “mystical interpretation” of the initial writings of the author.
FUNDUS AUTOFLUORSECNCE IN DIABETIC MACULAR OEDEMA
Authors: Pandit Uttara , Nagpal Shubha , Muzumdar Deepa
Published: July 2023

ntroduction: Diabetic macular oedema accounts for more than half the cases of vision loss in diabetics. With a shifting
trend on early diagnosis and treatment of DME, fundus autouorescence may prove to be valuable. Traditional methods
of 90d slit lamp examination and OCT may not detect early DME. The purpose of Purpose: this study was to evaluate fundus autouorescence
patterns in diabetic macular oedema and to assess the correlation with the severity of diabetic retinopathy. In this observational study Methods:
39 diabetic patients (70 eyes)who reported to the ophthalmology OPD of a tertiary hospital in Maharashtra underwent a detailed ophthalmic
evaluation. Patients with a central macular thickness of 212+/-20µm on OCT were included. Fundus picture and fundus autouorescence images
were captured. Poor quality images were discarded, and the remaining were analyzed and classied as various patterns. A total 39 Results:
diabetic patients were studied. The total number of males in the study were 24 and females were 15.Among the 73 eyes studied 12 Eyes had mild
NPDR (16%),38 Eyes moderate NPDR (52%),15 eyes severe NPDR (21%) while 8 eyes had PDR (11%). The most common type of pattern
noticed was cystoid increase seen in 35 eyes (48%). 26 eyes had single spot increase (36%) and none of the patients in our study had an irregular
decrease pattern. 12 eyes had diabetic macular oedema clinically and on OCT but normal autouorescence. (16%). Cystoid increase and single
spot increase patterns corelated with moderate and severe forms of NPDR. Patients with mild NPDR with DME showed no autoourscence
pattern. Conclusions: Diabetes is a debilitating disorder affecting all the organs in the body. The number of individuals with the disorder is on the
rise due to sedentary lifestyle and dietary habits.The gold standard for diagnosing DME remains fundus slit lamp bio microscopy. 1 Recently
optical coherence tomography (OCT) and fundus autouorescence have proved valuable in early detection of DME. Lesions can be hyperautouorescent, hypo-autouorescent , or iso-autouorescent. FAF might reect the damage of the retina and visualize photoreceptor integrity,
which gives an insight into status of the retina in DME. Dynamic FAF monitoring helps to better evaluate the disease progression of DME as
well as visual function. Since FAF does not require mydriasis, it is a faster and relatively inexpensive method of detecting DME.
DENTAL CROWDING AS A PREDISPOSING FACTOR IN RAPID CALCULUS FORMATION
Authors: Upadhyay Aditi , Kalla Kamakshi
Published: July 2023

Background: Dental crowding makes it challenging to maintain oral hygiene since there is food debris accumulation in
the interdental area which cannot be removed by regular brushing.Objective: To determine the prevalence of calculus
deposition among a population having dental crowding in the city of Hyderabad.Materials And Methods: This study
was conducted by OroGlee Solutions Private Limited, Hyderabad. A total of 1019 subjects aged 18 to 60 years were
examined and grouped based on the presence or absence of dental crowding and calculus. Results: Percentage of
people with dental crowding having calculus deposition was 57.9% and percentage of people without dental crowding
having calculus deposition was 45.2%.Chi square test was used to determine the significance of difference between the
prevalence of calculus in subjects with crowding and in subjects without crowding, which showed a statistically
significant correlation between dental crowding and calculus deposition. Conclusion: Crowding influences the oral
hygiene condition. It is mandatory to remove this calculus contributing factor to achieve an optimum level of oral
hygiene and decrease periodontal problems.
Design of High-Frequency, High-Power Class Φ2 Inverter Through On-Resistance and Output Capacitance Loss Reduction in 650 V Parallel eGaN Transistors for Optimal Thermal Performance
Authors: Sawant Kamlesh , Zhou Yu , Palanisamy Keerti , Choi Jungwon
Published: July 2023

This paper presents a class Φ2  inverters for high-power applications using multiple enhancement-mode gallium nitride (eGaN) switching devices operating at 13.56 MHz. The eGaN devices are beneficial in high-frequency, high-power applications such as plasma processing, thanks to the low switching and conduction losses. In addition, the small size of eGaN devices increases power density while reducing the impact of parasitic package components. However, their small package size makes it challenging to manage power dissipation, particularly at higher frequencies where additional conduction losses due to dynamic RDS(on) and switching losses due to COSS can significantly increase power dissipation. To address these challenges, we investigate the individual contributions of dynamic RDS(on) and COSS to power losses at high frequencies by paralleling multiple devices. We also propose criteria for selecting the optimum number of parallel eGaN devices to decrease power dissipation per device by reducing conduction losses greater than the addition in COSS losses. This approach helps to alleviate thermal stress in the devices. Finally, we demonstrate the effectiveness of our approach by designing a 1 kW single inverter and a 2 kW push-pull inverter at 13.56 MHz, which achieve over 90% drain efficiency while reducing thermal stress in the device.
STT-MRAM Technology For Energy-Efficient Cryogenic Memory Applications
Authors: Garzon Esteban , yavits leonid , Teman Adam , Lanuzza Marco
Published: July 2023

This work explores non-volatile (NV) embedded memories implemented by spin-transfer torque magnetic random access memories (STT-MRAMs). Our designs are based on state-of-the-art perpendicular magnetic tunnel junctions (MTJs) along with a commercial 65 nm planar CMOS Bulk technology node, both operating at the liquid nitrogen temperature, 77 K. We evaluate the impact of cooling down to 77 K of the STT-MRAMs based on single- and double-barrier MTJ (SMTJ and DMTJ), and DMTJ with the relaxed non-volatility. All NV designs were benchmarked against the six-transistor SRAM (6T-SRAM) baseline. Simulation analysis relies on a 512 kB cache memory operating at 77 K. Overall, results show that the implementation of STT-MRAMs with DMTJ devices, and in particular when using the non-volatility approach by reducing the cross-section area, excel in terms of energy consumption, leading to energy savings for write/read access of about 35%/54%. This saving is obtained while also dissipating less leakage power and requiring a smaller bitcell footprint. Moreover, it presents reduced write latency overhead (as much as 1.9 × lower), at the expense of increased read latency and reduced sensing margins of about 1.8 × and 88%, respectively. The results suggest that STT-MRAM technology can be a solid alternative for energy-efficient cryogenic memory applications. 