bluuebunny/crossref_metadata_2025 huggingface dataset:
Parental Support and Gender Moderate the Relationship Between Sexual Orientation and Suicidal Behavior in Adolescents
Authors: Pérez-Albéniz Alicia , Lucas-Molina Beatriz , Fonseca-Pedrero Eduardo
Published: November 2024

Background: :
The scientific literature indicates that people from sexual minorities may be at increased risk for mental health difficulties. Moreover, parental support could play a protective role against poor mental health. The objective of this study was to examine whether a person’s sexual orientation was related to a greater risk of mental health problems in a representative sample of adolescents. In addition, the study analyzed the possible moderating effect of parental support in the relationship between sexual orientation and mental health, as also moderated by participant gender.

Method::
The sample consisted of 1790 secondary-school students. Indicators of emotional and behavioral difficulties, psychotic-like experiences, suicidal behavior, well-being, and self-esteem were assessed.

Results: :
The results indicated significant main effects of gender and sexual orientation. Having a diverse sexual orientation (i.e., lesbian/gay, bisexual and questioning) was related to increased risk of mental health difficulties. Moreover, the results showed a significant interaction effect of gender and sexual orientation on suicidal behavior. Finally, the results showed the moderating effect of parental support and gender in the relationship between sexual orientation and suicidal behavior.

Conclusions::
These findings highlight the importance of promoting sexual minority youths’ mental health and well-being.
Self-Perceived Bullying Victimization in Pre-Adolescent Schoolchildren With ADHD
Authors: Morales-Hidalgo Paula , Hernández-Martínez Carmen , Voltas Núria , Canals-Sans Josefa
Published: November 2024

Background::
Bullying is highly prevalent among children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD). This study investigates self-perceived bullying victimization and related sociodemographic, psychopathological, cognitive, and academic characteristics in pre-adolescents with ADHD compared to controls.

Method::
The participants were 424 pre-adolescents, 138 of whom had ADHD. Self-perceived bullying victimization was assessed with the Bullying and School Violence questionnaire. This study is part of a larger double-phase epidemiologic cross-sectional study.

Results::
A total of 35% of the ADHD pre-adolescents self-reported bullying victimization. ADHD-combined presentation showed the highest prevalence of co-occurring self-perceived bullying victimization. After the effects of socioeconomic level, gender, place of birth, intelligence quotient and autism had been controlled, we observed that presenting ADHD increased the likelihood of self-perceived bullying victimization almost 3-fold. Having ADHD and self-perceived bullying victimization were significantly associated with higher rates of the co-occurrence of internalizing and externalizing psychological problems. Comorbidity with ASD was higher in ADHD + bullying cases. Pre-adolescents with ADHD had lower cognitive scores and worse academic outcomes regardless of whether they were being bullied or not.

Conclusions::
In bullying prevention and intervention, special attention should be paid to ADHD as a vulnerability factor for self-perceived victimization, with negative consequences for emotional well-being and behavior.
Development and Validation of the Brief Math Anxiety Scale (BMAS) in University Students
Authors: Núñez-Peña M. Isabel , Guilera Georgina
Published: November 2024

Background::
This study developed the Brief Math Anxiety Scale (BMAS), a brief version of the Shortened Math Anxiety Rating Scale (sMARS), maintaining its original three-factor structure, by applying item response theory.

Method::
The sMARS was administered to 1,349 undergraduates, along with other questionnaires to measure their math ability, trait and test anxieties, and attitudes toward mathematics.

Results::
Results showed that the original scale could be reduced to nine items (three for each subscale). We provided evidence of good psychometric properties: strong internal consistency, adequate 7-week test-retest reliability, and good convergent/discriminant validity.

Conclusions::
In conclusion, the BMAS provides valid interpretations and reliable scores for assessing math anxiety in university students, and is especially useful in situations with time constraints where the longer form is impractical.
Changing Attitudes About a Pro-Environmental Proposal Concerning Solar Power: The Self-Validating Role of Ingroup Versus Outgroup Sources
Authors: Santos David , Horcajo Javier , Gil Rafael , Guyer Joshua J.
Published: November 2024

Background::
In this study, we examined whether a persuasive message in favor of a pro-environmental proposal could influence attitude change through a self-validation process when individuals were told that the source of the proposal belonged to their ingroup (vs. their outgroup).

Method::
Participants read a message that advocated for the use of solar power. Immediately following the message, participants were asked to list their thoughts regarding the persuasive proposal. A thought favorability index was created for each participant. Following the thought-listing task, participants received the experimental manipulation (i.e., ingroup vs. outgroup source) based on the minimal group paradigm, after which they reported their attitudes towards the proposal.

Results::
A regression analysis showed the predicted interaction between thought favorability and type of source (i.e., ingroup vs. outgroup) on attitudes towards the solar power proposal. According to our expectations, thought favorability was a better predictor of attitudes for participants in the ingroup (vs. outgroup) source condition.

Conclusions::
Attitudes can be polarized as a function of ingroup versus outgroup differentiation through a self-validation process.
Structure of human PIEZO1 and its slow inactivating channelopathy mutants
Authors: Shan Yuanyue , Guo Xinyi , Zhang Mengmeng , Chen Meiyu , Li Ying , Zhang Mingfeng , Pei Duanqing
Published: November 2024

PIEZO channels transmit mechanical force signals to cells, allowing them to make critical decisions during development and in pathophysiological conditions. Their fast/slow inactivation modes have been implicated in mechanopathologies, but remain poorly understood. Here, we report several near-atomic resolution cryo-EM structures of fast-inactivating wild-type human PIEZO1 (hPIEZO1) and its slow-inactivating channelopathy mutants with or without its auxiliary subunit MDFIC. Our results suggest that hPIEZO1 has a more flattened and extended architecture than curved mouse PIEZO1 (mPIEZO1). The multi-lipidated MDFIC subunits insert laterally into the hPIEZO1 pore module like mPIEZO1, resulting in a more curved and extended state. Interestingly, the high-resolution structures suggest that the pore lipids, which directly seal the central hydrophobic pore, may be involved in the rapid inactivation of hPIEZO1. While the severe hereditary erythrocytosis mutant R2456H significantly slows down the inactivation of hPIEZO1, the hPIEZO1-R2456H-MDFIC complex shows a more curved and contracted structure with an inner helix twist due to the broken link between the pore lipid and R2456H. These results suggest that the pore lipids may be involved in the mechanopathological rapid inactivation mechanism of PIEZO channels.
Protonation/deprotonation-driven switch for the redox stability of low-potential [4Fe-4S] ferredoxin
Authors: Wada Kei , Kobayashi Kenji , Era Iori , Isobe Yusuke , Kamimura Taigo , Marukawa Masaki , Nagae Takayuki , Honjo Kazuki , Kaseda Noriko , Motoyama Yumiko , Inoue Kengo , Sugishima Masakazu , Kusaka Katsuhiro , Yano Naomine , Fukuyama Keiichi , Mishima Masaki , Kitagawa Yasutaka , Unno Masaki
Published: November 2024

Ferredoxin is a small iron-sulfur protein and acts as an electron carrier. Low-potential ferredoxins harbor [4Fe-4S] cluster(s), which play(s) a crucial role as the redox center. Low-potential ferredoxins are able to cover a wide range of redox potentials (−700 to −200 mV); however, the mechanisms underlying the factors which control the redox potential are still enigmatic. Here, we determined the neutron structure of ferredoxin from
Bacillus thermoproteolyticus
, and experimentally revealed the exact hydrogen-bonding network involving the [4Fe-4S] cluster. The density functional theory calculations based on the hydrogen-bonding network revealed that protonation states of the sidechain of Asp64 close to the [4Fe-4S] cluster critically affected the stability of the reduced state in the cluster. These findings provide the first identification of the intrinsic control factor of redox potential for the [4Fe-4S] cluster in low-potential ferredoxins.
Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage
Authors: Krwawicz J , Sheeba CJ , Hains K , McMahon T , Zhang Y , Kriaucionis S , Sarkies P
Published: November 2024

DNA methylation at the 5 position of cytosine (5mC) is an ancient epigenetic mark in eukaryotes. The levels of total 5mC vary enormously between different species, and the DNA methyltransferases that introduce 5mC have been repeatedly lost in several independent lineages. DNA methyltransferases are a threat to genomic stability due to the increased mutagenicity of 5mC bases and the propensity of DNA methyltransferases themselves to introduce DNA alkylation damage as an off-target effect. However, whether alkylation damage explains why 5mC is frequently lost in evolution is unclear. Here we tested the fitness consequences of DNA methyltransferase-induced alkylation damage by introducing a eukaryotic-like 5mC system into
E. coli
. We showed that introducing 5mC genome-wide leads to increased sensitivity to alkylating agents, which is strongly enhanced by removal of the 3mC repair enzyme AlkB. Unexpectedly, we discovered that 5mC introduction led to increased sensitivity to oxidative stress. We showed that this is due to increased formation of reactive oxygen in the presence of 5mC. We determined that reactive oxygen species led to non-enzymatic oxidation of 5mC, producing modified cytosines such as 5fC that are recognised as DNA base damage in
E. coli
. Overall, our work identifies increased sensitivity to oxidative stress, as well as alkylating agents, as a negative consequence of genome-wide 5mC. Oxidative stress is frequently encountered by organisms in their environment, thus offering a plausible reason for total loss of 5mC in some species.
TET2 contributes to gluconeogenesis and pathology of type 2 diabetes
Authors: Zhang Xinchao , Li Hongchen , Li Shuyan , Cui Ziyi , Zhao Xinyu , Ma Haijie , Xu Ming , Xu Yanping
Published: November 2024

The control of gluconeogenesis is critical for glucose homeostasis and the pathology of type 2 diabetes (T2D). Here, we uncover a novel function of TET2 in the regulation of gluconeogenesis. In mice, both fasting and a high-fat diet (HFD) stimulate the expression of TET2, and TET2 knockout impairs glucose production. Mechanistically, FBP1, a rate-limiting enzyme in gluconeogenesis, is positively regulated by TET2 in liver cells. TET2 is recruited by HNF4α, contributing to the demethylation of FBP1 promoter and activating its expression in response to glucagon stimulation. Moreover, metformin treatment increases the phosphorylation of HNF4α on Ser313, which prevents its interaction with TET2, thereby decreasing the expression level of FBP1 and ameliorating the pathology of T2D. Collectively, we identify an HNF4α-TET2-FBP1 axis in the control of gluconeogenesis, which contributes to the therapeutic effect of metformin on T2D and provides a potential target for the clinical treatment of T2D.
Accuracy of self-reported height, weight, and waist circumference in poor, rural areas of China
Authors: Cao Hongjuan , Zhang Zhuang , Zhang Junqing , Wang Quanzhi , Yu Liang , Xie Shaoyu , Zhang Li-Bing , Fu Hao , Li Kaichun , Shen Tianyi , Li Xiude
Published: November 2024

Objectives

There are differing opinions and findings about the accuracy of self-reported data. This study sought to assess the accuracy of self-reported height, weight, and waist circumference (WC) data among adult residents in poor, rural areas of China.

Methods

Multi-stage stratified cluster random sampling was used to sample rural adult residents in Jinzhai County. Intraclass correlations (ICCs), Bland-Altman plots with limits of agreements (LOAs), and Cohen’s kappa were used to examine the accuracy of self-reported data. Multiple linear regression was used to explore the effect of demographic and socioeconomic variables.

Results

Height was over-reported by an average of 0.67 cm, weight and WC were both under-reported, by an average of 0.004 kg and 1.09 cm, respectively. The ICC for height was 0.92, the ICC for weight was 0.93, and the ICC for WC was 0.93. Bland-Altman plots showed no trend in variability with increasing height, weight, and WC, but 95% of the LOAs were wide, especially for WC. The percentage agreement (kappa) for BMI was 82.10% (0.71), and the percentage agreement for WC was 83.56% (0.66). Overall, obesity, overweight, and increased WC were underestimated by 0.56%, 2.64%, and 6.89%, respectively. Assessments of which demographic and socioeconomic factors were associated with statistically significant differences between self-reported and measured data showed that education (junior school vs. primary or below: β = −0.56, 95% CI [−1.01 to −0.11]) and occupation (others vs. professionals: β = 2.16, 95% CI [0.62–3.70]) were associated with differences between measured and self-reported height; occupation (industrial and commercial service vs. professionals: β = 1.57, 95% CI [0.52–2.61]) was associated with differences between measured and self-reported weight; and gender (women vs. men: β = −1.74, 95% CI [−2.51 to −0.97]) and age (60– vs. 18–44: β = −1.62, 95% CI [−2.88 to −0.36]) were associated with differences between measured and self-reported WC.

Conclusions

Self-reported height and weight were shown to be reliable in poor, rural areas of China, but self-reported WC should be used with caution. To improve the accuracy of self-reported data, certain subgroups should be targeted for educational interventions.
miR-101-3p suppresses proliferation of orbital fibroblasts by targeting pentraxin-3 in thyroid eye disease
Authors: Zhu Yanfei , Chen Yuqing , Shu Xingyi , Wei Ruili
Published: November 2024

Background

Excessive proliferation of orbital fibroblasts (OFs) is an essential factor in the pathogenesis of thyroid eye disease (TED). While existing evidence indicates that various microRNAs (miRNAs) significantly contribute to TED development, the precise function and targets of miR-101-3p in TED pathogenesis remain unknown. This research aims to elucidate the effects of miR-101-3p on TED-OFs and identify its potential targets.

Methods

Orbital adipose tissues were harvested from both TED patients and healthy controls to culture their fibroblasts. MiR-101-3p mimic or mimic negative control (mimic NC) was transfected into OFs from TED patients, with untreated OFs serving as an additional blank control group. Cell proliferation was assessed using cell counting kit-8 (CCK-8) assay, Ki-67 immunofluorescence staining, and the EdU assay, while apoptosis was evaluated via flow cytometry. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to measure the expression levels of miR-101-3p and pentraxin-3 (PTX3), and PTX3 protein levels were quantified using western blot. A dual-luciferase assay was conducted to ascertain how miR-101-3p and PTX3 interacted.

Results

The results demonstrated a significant downregulation of miR-101-3p in fibroblasts and TED orbital adipose tissues. Transfection with the miR-101-3p mimic upregulated miR-101-3p levels, significantly reducing OFs proliferation without affecting apoptosis. Overexpression of miR-101-3p led to the downregulation of PTX3 in OFs. The dual-luciferase assay validated miR-101-3p binding to PTX3’s 3’UTR, thereby repressing its expression. Moreover, overexpression of PTX3 partially rescued the miR-101-3p mimic’s inhibitory effect on TED-OFs proliferation.

Conclusion

Our findings illustrate miR-101-3p’s role in targeting PTX3 to regulate TED-OFs proliferation, providing novel insights into the pathological mechanisms underlying TED development.
A Narrative Review on Brain Gym Exercises: An Asset in Alleviating Insomnia and Augmenting Cognitive Functioning
Authors: Thakre Vaishnavi Mukund , Deshmukh Mitushi
Published: November 2024

Insomnia is characterised primarily by difficulties with beginning or sustaining sleep, dissatisfaction with sleep duration and quality and significant discomfort and deficits in daytime activities. Females, elderly individuals and individuals experiencing socioeconomic hardships are prone to sleeplessness. Despite its widespread incidence and burden, the pathophysiology and aetiology of insomnia remain unclear. It also impacts cognition, mood, focus, healing and exhaustion. Psychological and medical conditions can cause insomnia. Non pharmacological treatments for this condition include Cognitive Behavioural Therapy for Insomnia (CBTI), acupressure, meditation and yoga. Brain gym exercise is an evolving therapeutic approach to alleviate insomnia. By engaging in brain gym exercises, individuals may experience improvements in their sleep patterns, leading to better overall sleep quality and duration and may experience enhancements in their ability to think, learn and perform cognitive tasks effectively. The review concludes that incorporating brain gym exercises offers notable benefits for both insomnia and cognitive functioning.
Sterilisation of Dental Implant Surgical Instruments, Office Area and Implant Components: A Narrative Review
Authors: Gupta Deepesh Kumar , Seethal K , Kerketta Jenifer , Anant Mahendra Kumar , Vattigunta Sravani
Published: November 2024

Implant surgical procedures require meticulous attention to sterilisation protocols to prevent infections and ensure successful outcomes. Various sterilisation methods, such as steam sterilisation, ethylene oxide sterilisation and hydrogen peroxide plasma sterilisation, are commonly used in healthcare facilities. Each method has its advantages and limitations and the selection of a sterilisation method depends on factors such as the type of implant material, instrument design and compatibility with the sterilisation process. Proper handling, packaging and storage of implant surgical components and instruments are essential to maintain their sterility until they are used. Healthcare facilities must follow standardised protocols and guidelines to ensure the effective sterilisation of implant surgical components and instruments, ultimately reducing the risk of infections and improving patient outcomes. Controversies exist regarding the reusability of healing abutments, with some advocating for single-use only to reduce the risk of contamination, while others argue for reusability under stringent sterilisation protocols. Further research is needed to establish clear guidelines on the reuse of healing abutments in implant surgery. The sterilisation of implant surgical components and instruments is a critical aspect of implant surgery that requires careful consideration of sterilisation methods and adherence to established protocols. Addressing the controversies surrounding the reusability of certain components, such as healing abutments, is essential to ensure patient safety and improve surgical outcomes.
The Impact of Farmers' Social Lifestyles on Agricultural Sustainability in Rural Area of Turkey
Authors: Akdemir Şinasi , Koca Fatih , Baskın Sami , Miassi Yann Emmanuel , Kougnigan Elpidio , Dossa Kossivi Fabrice
Published: November 2024

This study investigates how farmers' social lifestyles influence agricultural sustainability in rural Turkey. Through data analysis from 312 producers across five provinces, we examine how participation in social activities such as religious gatherings, café meetings, and agricultural fairs shapes farming decisions and sustainability outcomes. Using logistic regression modeling, we find that social network participation significantly impacts agricultural performance and sustainability practices. Results reveal that different types of social engagement lead to distinct patterns of innovation adoption and resource management. Coffee-house and religious gatherings influence not only sales decisions but also agronomic practices, such as adopting new technologies and innovative methods. The lack of female involvement and potential pathways for their integration are also important. This research provides crucial insights for policymakers seeking to leverage existing social networks to promote sustainable agricultural practices in rural communities.
Assessment of Service Satisfaction at Amul Preferred Outlets (APOs) with Respect to Vasudhara Dairy's Staff Society Offerings
Authors: Garasia Ritik , Lad Yogesh Kumar A.
Published: November 2024

The Indian dairy industry is responsible for the world's largest milk production, with key players including Amul, Mother Dairy, and others. Amul Parlours are special establishments where the complete line of Amul goods are kept and sold. Understanding the constraints and challenges faced by Amul parlour owners is vital for the improvement of Amul. This paper examines the satisfaction of Amul Preferred Outlets (APOs) owners with the services provided by Vasudhara Dairy - Staff Society. Primary data were gathered with the help of a questionnaire. A sample size of 98 from three districts (Valsad, Navsari, and Dang) was selected for this study. The results of the study show that APO owners usually have no problems with placing orders or receiving them on time. However, there is room for improvement in terms of lowering the number of broken products delivered, ensuring accurate product lists, delivering products in case of emergency, and handling orders that are ignored. It was observed that APO owners express interest in new product categories such as ready-to-eat, ready-to-cook, non-dairy beverages, protein-enriched products, and dairy-based desserts.
O Impacto Das Tecnologias Educacionais No Ensino Básico E Médio, Uma Análise Bibliométrica Da Literatura
Authors: Santos Raphael Sapucaia Dos , Santana José Ricardo De
Published: November 2024

O uso de tecnologia na educação básica tem se mostrado crescente nos últimos anos. O presente trabalho analisa a produção bibliográfica sobre o uso de tecnologias na educação, focando nos níveis do ensino fundamental e médio, com o objetivo de identificar e compreender o debate de ideias nas publicações sobre o tema. Os dados foram coletados da base de dados Scopus. Os termos foram digitados em inglês e pesquisados nos campos de títulos, resumos e palavras-chave. O intervalo temporal estudado foi de 2010 a 2023. Realizamos três buscas, encontrando 2709 publicações na primeira, 176 na segunda e 99 na terceira, todas alinhadas ao objetivo deste artigo. Os resultados foram analisados no Excel e a nuvem de palavras foi gerada no VOSviewer. Os resultados em relação à nuvem de palavras destacam as palavras "teacher" com 54 ocorrências e "learning" com 49 registros. A análise bibliométrica indica uma tendência de crescimento em pesquisas sobre o uso de tecnologias na educação básica e no ensino médio, sendo que a maioria das publicações ocorreu no Brasil. As publicações focaram principalmente em aprendizagem, com 82 registros, representando 82,83%, e o subtema 'Percepção do Aluno' foi o mais frequente com 28 publicações
Active Methodologies In Higher Education
Authors: Cardoso Fernando Mendonça , Rosa Carlos Gustavo Sakuno , Ferreira Sara Brigida Farias , Carvalho Ricardo De Oliveira , Basniak Silvéria Aparecida
Published: November 2024

Active methodologies are the educational conception that enables the higher education student to be the protagonist of his learning. The present study aims to analyze the active methodologies that can be used in the context of higher education, aiming to facilitate and qualify the learning of students. In this sense, some of these methodologies considered innovative today are presented, as well as the flipped classroom, problem-based learning and project-based learning, through a qualitative-bibliographic-research. The work had as theoretical foundation some current and relevant books and articles, which were found in the "Google Scholar" database. The selected materials were analyzed and interpreted for the preparation of the article. With this study, it was found that active methodologies allow the teaching and learning process to be developed through significant and useful pedagogical practices for the students' lives. Thus, in this perspective, such a process can favor critical and reflective thinking, autonomy, problem-solving skills, group work and the active participation of students during classes. Therefore, it is understood that the flipped classroom, problem-based learning and project-based learning are modalities of active methodologies that can be used in Higher Education. These can promote participating, collaborative subjects and producers of their knowledge, aiming to facilitate and qualify students' learning.
Forecast Of Rainfed Agricultural Production In The State Of Pernambuco, Brazil
Authors: Paiva Elizama Cavalcante De , Sousa Erika Costa , Araujo Jair Andrade De , Lemos Jose De Jesus Sousa , Feitosa Milena Monteiro
Published: November 2024

This research assesses rainfed agricultural production in the state of Pernambuco, which has 137 of its 185 municipalities officially characterized as being part of the semi-arid climate regime. The study classified rainfall periods in Pernambuco between 1944 and 2022 and investigated rainfall instability and its impact on aggregate productivity, aggregate harvested area and production value per hectare of bean, cassava and maize crops. The Auto-Regressive Integrated Moving Average model with Exogenous Variable Inputs (ARIMAX) was used, considering rainfall as an exogenous variable. The results showed that rainfall has a direct effect on the variables investigated, especially the harvested area. It was proven that in periods classified as normal and rainy, productivity, harvested area and production value per hectare showed higher results than those observed in the dry periods of, as was the assumption of the research. The study also confirmed that the models developed were parsimonious and capable of predicting the variables investigated. The results showed that productivities, harvested areas and production values per hectare for beans, cassava and corn experienced greater instability during periods of drought. The research also shows that the aggregated production values per hectare for the three crops are very low. In dry years, they are even lower than the minimum wage. This result confirms that the rural areas of Pernambuco where these crops are mostly grown are very poor
Educação E Lei 10.639/2003: Contribuições Da Cultura Afro-Brasileira E Africana No Currículo Escolar Para O Combate Ao Racismo
Authors: Santos Anita Terezinha Scaranello Dos , Mendes Paulo César , Rodrigues Graziele Azevedo , Dani Leandro , Sousa Francisco José Lourenço De
Published: November 2024

A pesquisa teve como objetivo investigar a implementação da Lei 10.639/2003 e a inclusão da cultura afrobrasileira e africana no currículo escolar, analisando a percepção de 23 professores sobre essa temática. Utilizou uma abordagem qualitativa, por meio de uma metodologia exploratória e descritiva, com coleta de dados realizada através de entrevistas que foram analisadas por meio da análise do discurso. Os resultados revelaram que, embora haja uma conscientização crescente sobre a importância da inclusão da cultura afro-brasileira, persistem desafios significativos, como a falta de formação adequada para os educadores, resistência de alunos e colegas, e a escassez de recursos didáticos. No entanto, muitos professores estão adotando práticas pedagógicas inovadoras que promovem a valorização da cultura afro-brasileira, contribuindo para o engajamento dos alunos e para a construção de um ambiente escolar mais inclusivo. A conclusão destaca que a implementação da lei deve ser encarada como uma oportunidade de promover a equidade e a justiça social, enfatizando a importância de um compromisso coletivo para garantir que a educação antirracista se torne uma realidade efetiva nas escolas e na sociedade
The Therapeutic Approach To Complexes Created By The Primary Drive Of Intense Desire (Prospatheia): An Introduction To Neptic Psychology
Authors: Karatzas Andreas
Published: November 2024

This paper examines the concept of "prospatheia" and its relationship to the creation and management of psychological complexes, drawing on elements from both Neptic Theology and psychology. Prospatheia, as a powerful longing for connection, is considered a primary drive leading to emotional attachment and contributing to the formation of complexes. In psychology, complexes are interpreted as unconscious patterns that guide behavior, reinforcing dependence on external sources to fulfill fundamental emotional needs. The approach of Neptic Theology proposes a therapeutic process that differs from the psychological acceptance or integration of complexes. Specifically, Neptic Psychology emphasizes the prevention of complex formation from childhood through training the individual to develop a more measured relationship with the material world, avoiding excessive pleasure. In adulthood, Neptic Psychology supports controlling prospatheia through the conscious avoidance of pleasure, which sustains dependence. Thus, the treatment of complexes involves three phases: prevention, pleasure control, and gradual weakening of the complexes. Focusing on the abandonment complex, the paper illustrates how excessive reliance on security can transform into a fear of abandonment, leading to emotional insecurity and alienation from one’s spiritual nature. Neptic Theology advocates for self-control and the avoidance of pleasure that reinforces complexes, thereby fostering an inner balance. This methodology differs from modern psychological methods, as it aims at the weakening rather than the acceptance of complexes, offering a unique framework for understanding the human soul and its relationship to the material world.
Recurrent Urinary Tract Infection In A Diabetes Mellitus Patient On Dapagliflozin: A Case Report
Authors: Moloo Sakina , Lwabukuna Warles
Published: November 2024

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Multiple Compound Composite Odontomas Of The Maxilla: A Report Of Two Cases
Authors: A J Dr.Jubna. , T V Dr.Anupam Kumar. , M T Dr.Jeseem. , Nazneen Dr.Amina.H. , P T Dr.Ikram Bin Ismail
Published: November 2024

Odontomas are benign mixed odontogenic tumours, considered to be developmental anomalies resulting from the growth of differentiated epithelial and mesenchymal cells. It is the most common benign odontogenic tumour, usually asymptomatic and are often discovered during routine radiographic examinations. It can occur at any age, but are most common in the first two decades of life. It is more commonly seen in the anterior maxilla and frequently cause delayed eruption of teeth or retention of primary teeth. Morphologically odontomas are classified as compound and complex odontomas, in which the former resembles teeth whereas the latter being an irregular mass. This paper describes two cases of compound composite odontomas of anterior maxilla in 10 year old and 5 year old patients, with detailed clinical presentation, histopathological features and treatment aspects.
Aspects Epidemio-Cliniques Et Paracliniques Du Paludisme Grave Chez Les Enfants En Detresse Vitale : Une Etude Retrospective Et Multicentrique De Cas Dans La Ville De Kinshasa (RDC)
Authors: Mg Monkoti Manzi , J sibu C. || Bodi , T Lunguya O. || Mabela , A Keto , J Balekelayi , . Lembalemba , A Bikoumou
Published: November 2024

Contexte : La prise en charge précoce du paludisme grave débute par le diagnostic ou la reconnaissance précoce de la maladie surtout chez les enfants en détresse vitale. L’objectif était d’établir le lien entre les paramètres cliniques et biologiques. Méthodes : Il s’agit d’une étude quasi expérimentale, multicentrique qui a examinée 116 dossiers d’admission pédiatrique pour paludisme grave que nous avons suivie sous un protocole standardisé au cours de la période de 18 mois allant du 4 mars 2014 au 5 Aout 2015 ; dans 4 formations sanitaires de la ville province de Kinshasa, capitale de la République Démocratique du Congo, où le paludisme sévit de manière endémique. Résultats : Sur un total 67 enfants avec paludisme grave nous avons écarté 17 chez qui une bactériémie était confirmée aux hémocultures et avons donc retenu 50 enfants. Les principales manifestations cliniques à l’admission étaient : pâleur (n=38, 76%), détresse respiratoire (n=19, 38%), splénomégalie (n=17, 34%), hépatomégalie (n=15, 30%), ictère (n=6, 12%) et convulsions (n=6, 12%). La biologie était essentiellement marquée par une moyenne de GB = 10942±8082,3/ mm3, une formule leucocytaire pathologique chez 82% d’enfants. La moyenne de plaquette = 189920±100644,4 µ/l ; CRP = 44,1±15,1 mg/l ; Hb = 7,2±2,1 g/dl, Ht = 22,8±6,5% et glycémie = 71,1±48,3 mg/dl. La détresse respiratoire, la splénomégalie, l’ictère, l’anémie sévère et l’hypoglycémie étaient significativement associés à la forte parasitémie (p<0,05) avec un risque élevé. Conclusion : Ce travail a confirmé le lien entre les signes cliniques, biologie de gravité du paludisme et la forte densité parasitaire. Ces données peuvent être utilisées en milieu à faible ressources pour une prise en charge rapide en situation d’urgence.
Improving Quality Of Life Through Prosthodontic Intervention In Ectodermal Dysplasia: A Case Report
Authors: Varshney Dr. Shraddha , Sharma Dr. Sanjay Kumar , Kohli Dr. Tanya , Gupta Dr. Utkarsh
Published: November 2024

Ectodermal dysplasia (ED) is a rare inherited disorder that affects ectodermal tissues such as hair, nails, teeth, and skin. Dental symptoms often include missing (anodontia) or reduced (hypodontia) primary and permanent teeth, conical teeth, and underdeveloped alveolar ridges. These orofacial issues frequently lead to psychosocial challenges, making the restoration of appearance and function particularly demanding. Hypohidrotic (anhidrotic) ED and hidrotic ED are the two most common syndromes in this group. The most prevalent form of ectodermal dysplasia is hypohidrotic ectodermal dysplasia (HED), which occurs in approximately one in every 100,000 infants. The primary symptoms of HED include hypohidrosis (reduced ability to sweat), hypotrichosis (sparse hair), and partial anodontia (missing teeth). Common facial features of ED include frontal bossing, sunken cheeks, saddle nose, thick everted lips. Treatment options for ED include removable, fixed, or implant-supported prostheses, either alone or in combination. This report describes the prosthetic rehabilitation of a patient with ED, focusing on improving both function and aesthetics
Temporomandibular Joint Ankylosis In True Hemifacial Hyperplasia With Infiltrative Lipomatosis - A Case Report
Authors: Raj Dr.Anju S , K S Dr.Ravindran Nair , Ismail.P T Dr.Ikram Bin , P Dr.Seeja , R S Dr.Ram Mohan , O Dr.Fasalulla
Published: November 2024

Congenital infiltrative lipomatosis of the face is a benign condition in which mature adipocytes invade adjacent tissues causing diffuse fatty infiltration into the surrounding soft tissue and hyperplasia of the adjacent bone on the affected side. This case report of a 37-year-old female with congenital facial asymmetry and diffuse swelling on the right side of the face suggests true hemifacial hyperplasia, which is supported by both clinical and radiographic data which showed severe involvement of underlying bony structures of the temporomandibular joint, sphenoid, temporal, zygoma, right maxilla, mandible, associated dentition and adjacent soft tissues. It also revealed lipomatous enlargement with right temporomandibular joint ankylosis reported with multiple etiological factors and marked trismus, for which functional rehabilitation was achieved following surgical intervention
Knowledge, Attitude And Practice In Oral Cancer Among Dental Hygienists In Libya
Authors: Ateia Gamal H. , Mussa Asma M. Ali , AL-Shiky Sarah Almahdi , Badir Najwa Mustafa , AL-Kawafi Marwa Mustafa
Published: November 2024

Background: Oral cancer remains a global health problem. Lack of awareness leads to inadequate watchfulness regarding early signs/symptoms despite the ease of visual oral inspection. Dental hygienists play an important role in early detection of oral cancerous lesions. Evidence on the awareness and knowledge level of oral cancer and its associated risk factors among dental hygienists in Libya is scarce. The aim of this study was to assess knowledge, attitudes, and practice (KAP) regarding OC among dental hygienists in Libya. Materials and methods: Administered questionnaires were distributed on dental hygienists (through Google Forms). The questionnaire included four sections: sociodemographic information, oral cancer knowledge, attitudes toward oral cancer, and clinical practices related to oral cancer. Participants' responses to the questionnaire were analyzed using descriptive statistics. Results: Responses were received from 100 participants (60% women and 40% men). Overall, there is a good knowledge of the real risk factors among the participants (86%, 83%, and 71%) regarding the following risk factors smoking, alcohol, and poor diet respectively. The analyze related to the knowledge of non- risk factors, Just over half of the respondents correctly indicated that family history, poor oral hygiene, and poor fitting prosthesis are not risk factors for OC onset (57%; 55%; and 51%, respectively). The majority of respondents (80% & 77% respectively) correctly identified leukoplakia and erythroplakia as oral potentially malignant disorders. The totality 81% of DHs believed they needed continuous updates in the future. With regard to practice, high percentage of DHs stated to perform an extra/intraoral examination and carried out palpation of the lymph nodes. Conclusions: Overall, this study highlighted the importance of introducing continuous education and training courses to dental hygienists which could increase oral cancer prevention and survival rates among oral cancer patients
The Green Infrastructure Model Based On Waterlogging Mitigation In The Street Landscape Of Sungai Penuh City, Jambi Province
Authors: Hendayu Bintang Dipratama , Sulistyantara Bambang , Purwanto Yanuar Jarwadi
Published: November 2024

Background: In many cases, the planning of public and social space in Indonesia is not accompanied by the planning of green open space, which is their functions as a healthy environmental balancer. One of the public spaces is the street landscape. This results in to the impact of natural phenomena such as floods, waterlogging in the rainy season, and hot weather in summer. The purpose of this study is to provide an overview of the Green Infrastructure model of roads, can also function as a place to anticipate waterlogging, flooding, air quality improvement, and human-friendly designation. Materials and Methods: The methodology was carried out through field inventory, mapping based on Shp ArcGis data, and a modified literature study. The location of the research is on roads spread across 8 subdistricts of Sungai Penuh City, Jambi Province. Results: Based on government administration and axis content, the public roads of Sungai Penuh City are categorized into class III Provincial Roads. The number of road sections in Sungai Penuh City is 49 (forty-nine) road sections. The details are that the primary collector road landscape consists of 11 road sections, the secondary collector road landscape consists of 12 road sections, and the local road landscape is very dominant, which is as many as 26 roads. The total length of the entire Sungai Penuh City road section is 51.43 km with an average width of 6 meters. Based on the level of urgency, the results of the assessment of priority sub-districts determined 31 road sections spread across Sungai Penuh District, Sungai Bungkal District, and Pondok Tinggi District as priority sub-districts for the implementation of the Green Infrastructure system. Based on hydrological calculations of rainfall for the last 20 years (2003-2023). Conclusion: The Green Infrastructure Model is prioritized for 3 sub-districts. Based on the assessment of the Green Infrastructure Implementation Indicator, two green infrastructure concepts are applied, namely Green Stormwater Infrastructure 1 (GSI 1) and Green Stormwater Infrastructure 2 (GSI 2) which are equipped with the Complete Street concept. The GSI 1 system is applied on 24 roads in Sungai Penuh City using the Stormwater Tree Trench and planter. The GSI 2 system consisting of Stormwater Bump-Out, Stormwater Tree Trench, and Stormwater Planter and the Complete Street concept will be applied on 7 roads in Sungai Penuh City
Addressing Infrastructure Design Challenges In Constructing At-Grade Rail Crossings Near Road Intersections
Authors: Anagnostopoulos Apostolos
Published: November 2024

At-grade rail crossings, where railway tracks intersect roadways at the same level rather than being separated by bridges or tunnels, are crucial elements of transportation infrastructure. However, these crossings create significant challenges for rail operations, particularly regarding safety and efficiency. Locating an at-grade rail crossing near a road intersection is generally discouraged due to the increased risk of train delays, reduced visibility for train operators, and the potential for train-road conflicts. While these issues are undesirable, they are sometimes unavoidable when rail infrastructure must be near or across road intersections. This study examines the design challenges of constructing at-grade rail crossings near road intersections. It provides a comprehensive review of the safety and operational concerns, including delays, conflicts, and the potential for accidents. The study also discusses existing guidelines and design practices to mitigate these challenges, offering insights into improving the efficiency and safety of at-grade rail crossings near road intersections.
Hazards Analysis And Control Points In Chicken Meat
Authors: El-Sayed Jilan A. , Elsamahy Salah K. , Moussa-Ayoub Tamer E. , Gaballa Amal A.
Published: November 2024

Chicken is one of the fountain sources of amino acids, vitamins (such as vitamin A), and minerals. This study's objective was to analyze the chemical and microbiological hazards and the application of treatment methods to reduce hazards. The data showed that all samples were positive for pathogenic bacteria with counts ranging from 5.39 to 6.68, 3.26 to 4.21, 6.07, to 7.30 and 6.0 to 7.46 CFU/g of staph. aureus, salmonella spp., E. coli and psychrophilic bacteria, respectively. Lactic acid has a bactericidal effect on microorganisms. The data also reflect that all raw chicken samples contain residues of norfloxacin antibiotic with a range from 1.20 to 8.10 µg/kg and significant differences between samples, while oxytetracycline was detected in 22.2% only of tested samples. Also, all samples had residues of estradiol and estrogen residues. Boiling, grilling, and freezing can reduce antibiotic and hormone residues. The elements concentrations in the livers were higher than in muscle samples. The potential chemical risk assessment of the investigated sample may lead to severe toxicological implications.
Sustainable Rain Solutions And Microbial Safety Research For Indian Water Crisis
Authors: Qader Faisal Abdul , Khan Zainab , Baig Ahmed Mirza Zuhair , Shuttari Syed Sheham Mohiuddin , Arsal Mohammed Mudassir Hussain
Published: November 2024

Environmental Impact Awareness has always been the forefront of many surveys and solutions while trying to find the perfect know-it-all answer to the bigger question- “What do we have and What is getting depleted and finished?”. Water scarcity remains a pressing issue in arid and semi-arid regions of India, making rainwater harvesting a critical solution. This research investigates rainwater harvesting as a means to enhance water security, focusing on its benefits for water supply, flood risk reduction, and climate change mitigation. The paper outlines the stages of rainwater collection, transportation, and storage, emphasizing the technology required for active implementation while addressing sustainability concerns. Additionally, it reviews regulations such as the National Water Policy and microbial safety standards from the Bureau of Indian Standards (BIS) to ensure safe water. Findings on microbial testing, filtration technology, and community engagement for water conservation demonstrate a dual approach to water protection and public health. This study argues that rainwater harvesting not only serves as a water source but also has implications for antimicrobial resistance (AMR) in both potable and agricultural water. Ultimately, this work supports rainwater harvesting as a vital strategy for climate resilience and sustainable development in water-scarce regions
Os Impactos Das Práticas Da Governança Social, Ambiental E Corporativa (ESG) Sobre O Desempenho Empresarial
Authors: Nunes Kennya Rodrigues , Oliveira Diego Leme De , Lima José Ronyere De Freitas , Carvalho Francisco Silva Antônio De , Celuppi Fernanda Eméri Mokfa Matitz
Published: November 2024

A pesquisa teve como objetivo investigar os impactos das práticas de governança ambiental, social e corporativa (ESG) sobre o desempenho empresarial, explorando as percepções de gestores sobre o tema. Utilizou-se uma abordagem qualitativa e exploratória, com entrevistas em profundidade realizadas com quinze gestores selecionados por conveniência, cujas respostas foram analisadas por meio da técnica de análise do discurso. Os resultados mostraram que, apesar dos desafios iniciais, como os custos e a complexidade de implementação, as práticas ESG proporcionam benefícios significativos, incluindo fortalecimento da reputação, retenção de talentos e atração de investimentos. As dimensões ambiental, social e de governança foram identificadas como pilares estratégicos, contribuindo para a inovação, a eficiência e a resiliência organizacional. A pesquisa concluiu que a adoção de ESG não é apenas uma exigência externa, mas um modelo de gestão que favorece a sustentabilidade e a competitividade a longo prazo, reforçando o valor social e econômico das organizações