bluuebunny/crossref_metadata_2025 huggingface dataset:
Kontrazeptionsberatung: Die ärztliche Toolbox muss auch für Adoleszentinnen das gesamte Spektrum der reversiblen Verhütungsmethoden beinhalten
Authors: Renteria Saira-Christine
Published: March 2023

Zusammenfassung. Bei der Beratung von Jugendlichen ist Einfühlsamkeit und eine altersentsprechende Information zur ärztlichen Schweigepflicht wichtig. Das Eingehen auf die individuellen Bedürfnisse und Wünsche ermöglicht den gezielten Einsatz der notwendigen Informationen und Ressourcen und ist die beste Garantie für eine auf Zeit erfolgreiche Verhütung. Ziel ist das Treffen informierter Entscheidungen und das positive Erleben einer erfolgreich geschützten sexuellen und reproduktiven Gesundheit. Die Palette geeigneter Kontrazeptionsoptionen ist sehr breit. Um dieses Potenzial auszuschöpfen, sollten möglichst alle Methoden mit ihren Vor- und Nachteile angesprochen werden, inklusive Informationen zu sexuell übertragbaren Infektionen und Schutz davor. Bedenken und Fragen sollten umfänglich und ergebnisoffen beantwortet und den geschilderten Erfahrungen mit der Sexualität soll vorurteilsfrei begegnet werden. Nicht selten ist dies auch eine Gelegenheit, über erlebte Übergriffssituationen zu sprechen.
Verhüten bis es (fast) zu spät ist – Gründe und Konsequenzen eines Aufschubs der Elternschaft
Authors: Moffat Rebecca , Raggi Anna , Sartorius Gideon
Published: March 2023

Zusammenfassung. Die Anzahl Frauen, die gewollt oder ungewollt kinderlos bleiben, nimmt zu. Die Ursachen sind vielfältig. Das Wissen um die physiologische Abnahme der Fruchtbarkeit mit dem Alter ist begrenzt. Die Tatsache, dass die Fruchtbarkeit bereits ab dem 32. Lebensjahr signifikant abnimmt, ist vielen Frauen und auch manchen Ärztinnen und Ärzten nicht bewusst, und die Effizienz der In-vitro-Techniken wird überschätzt. Abgesehen vom Alter gibt es bisher keinen Prädiktor der zukünftigen Fekundität. Ärztinnen und Ärzte sollten sich bei der Diskussion über gesellschaftliche Einflüsse betreffend Alter der Mutter bei der ersten Geburt und den Umgang damit engagiert einbringen. Unsere Patientinnen brauchen nicht nur eine verlässliche Kontrazeptions- sondern auch eine verlässliche Fertilitätsberatung.
CME Sonografie 107: Sonografische Ellenbogenfälle CME-Fragen
Authors: Tamborrini Giorgio , Naňka Ondřej , Ricci Vincenzo
Published: March 2023

Zusammenfassung. In diesem Artikel besprechen wir exemplarische sonografische Beispielpathologien am Ellenbogen anterior, lateral, medial und posterior mit Hervorhebung wichtiger Strukturen, die im Bereich der entsprechenden Ellenbogenregion systematisch untersucht werden sollten.
CME Sonografie 108: Die Achillessehne im Ultraschall: Sonoanatomie und Pathologien CME-Fragen
Authors: Weidermann Frances , Hirschmüller Anja , Tamborrini Giorgio
Published: March 2023

Zusammenfassung. Die Achillessehne ist die dickste Sehne des menschlichen Körpers. Durch ihre oberflächliche Lage und die hohe Prävalenz von Pathologien in diesem Bereich ist sie eine der am häufigsten sonografierten Sehnen überhaupt. Als kostengünstiges und schnell verfügbares diagnostisches Tool ist die Sonografie als Untersuchungsmethode der bei Sportlern und Nicht-Sportlern gleichermassen vorkommenden «Achillodynie» nicht mehr wegzudenken. Mit den modernen, hochauflösenden Ultraschallgeräten lässt sich die Faserstruktur der Achillessehne ultrastrukturell so detailliert darstellen, dass hieraus der Begriff der «Sonohistologie» entstanden ist. Mittels Dopplersonografie und Elastografie können darüber hinaus Sehneneigenschaften visualisiert werden, die keine andere Modalität aufzeigen kann. Auch in der Therapie der verschiedenen Pathologien der Achillessehne hat sich die Sonografie zur Optimierung der Interventionen etabliert. In diesem Beitrag werden die sonografischen Aspekte der häufigsten Erkrankungen der Achillessehne – degenerativer und traumatischer Art – aufgezeigt und erörtert.
Seltene Ursache für B-Symptomatik
Authors: Rosenstock Piet , Komarek Charlotte , Rodriguez-Calero Antonio , Oestmann Andreas
Published: March 2023

Zusammenfassung. Die 78-jährige Patientin wurde nach dreimonatiger Verschlechterung ihres Allgemeinzustands bei B-Symptomatik, anhaltend erhöhten Entzündungswerten, progredienter Anämie und Niereninsuffizienz von ihrem Hausarzt zur Tumorsuche überwiesen. Angesichts der zuvor entdeckten pulmonalen Noduli und der neu diagnostizierten Mikrohämaturie vermuteten wir eine Vaskulitis, die wir serologisch (erhöhte MPO-ANCA) und bioptisch bestätigen konnten. Unter Steroidtherapie und Cyclophosphamid konnte eine Remission erzielt werden.
Differentiating Abnormal, Normal, and Ideal Personality Profiles in Multidimensional Spaces
Authors: Gutiérrez Fernando , Peri Josep Maria , Aluja Anton , Baillés Eva , Sureda Bárbara , Gutiérrez-Zotes Alfonso , Vall Gemma , Calvo Natalia , Ferrer Marc , Cavero Myriam , Mallorquí Aida , Villamón Silvia Edo , de Alba Amanda Meliá , Rodríguez M. Ángeles Ruipérez
Published: March 2023

Abstract: Current dimensional taxonomies of personality disorder (PD) establish that intense traits do not suffice to diagnose a disorder, and additional constructs reflecting dysfunction are required. However, traits appear able to predict maladaptation by themselves, which might avoid duplications and simplify diagnosis. On the other hand, if trait-based diagnoses are feasible, it is the whole personality profile that should be considered, rather than individual traits. This takes us into multidimensional spaces, which have their own particular – but poorly understood – logic. The present study examines how profile-level differences between normal and disordered subjects can be used for diagnosis. The Dimensional Assessment of Personality Pathology – Basic Questionnaire (DAPP-BQ) and the Personality Inventory for DSM-5 (PID-5) were administered to a community and a clinical sample each (total n = 1,925 and 3,543 respectively). Intense traits proved to be common in the general population, so empirically-based thresholds are indispensable not to take as abnormal what is at most unideal. Profile-level parameters such as Euclidean and Mahalanobis distances outperformed individual traits in predicting mental problems and equaled the performance of published measures of dysfunction or severity. Personality profiles can play a more central role in identifying disorders than is currently acknowledged, provided that adequate metrics are used.
Fully Controlled 6 Meters per Pixel Equatorial Mosaic of Mars From Mars Reconnaissance Orbiter Context Camera Images, Version 1
Authors: Robbins Stuart J. , Kirchoff Michelle R. , Hoover Rachael H.
Published: March 2023

NASA's Mars Reconnaissance Orbiter (MRO) spacecraft has operated around Mars since March 2006. The Context Camera (CTX) aboard MRO has returned >125,000 images of Mars, mostly at 5–6 m per pixel (mpp), providing ≈99% coverage with good‐quality images. Reconstruction of MRO's orbit and camera pointing from ground tracking are offset from the Mars global coordinate system. This work focuses on correcting those data for the more than 50,000 images in the equatorial region of Mars, between ±30° latitude, which comprises 50% of Mars' surface area. Determining and making these corrections in a relative control (image‐to‐image) and absolute or full control (image‐to‐ground reference) greatly improves the utility of the image data. Based on this work, the 95th percentile of tie points were offset from the Mars coordinate system by ≈155 m, corresponding to ≈28 CTX pixels. Controlling the more than 50,000 images was accomplished through an efficient, automated approach with additional manual input and validation, described herein. The mosaic was generated with semi‐manual image order from these controlled data and is provided at both 6 mpp and 100 mpp. The mosaic is available to the community through NASA's Planetary Data System Imaging & Cartography Annex.
New Insight Into the Transition From a SAR Arc to STEVE
Authors: Gillies D. M. , Liang J. , Gallardo‐Lacourt B. , Donovan E.
Published: March 2023

In this study, we present an analysis of the spectral transition of a Stable Auroral Red (SAR) arc to Strong Thermal Emission Velocity Enhancement (STEVE) emission observed by the Transition Region Explorer (TREx) Spectrograph on the night of 10 April 2022, recorded overhead in Lucky Lake, Saskatchewan. On this night, we see an unusually bright (∼2 kR) SAR arc with enhanced ionospheric flow channels in the conjugate southern hemisphere. Over a short time, on the order of minutes, we observe the spectra change from the typical SAR arc pure redline (630 and 636 nm) emission to the air glow continuum, a broadband enhancement across all wavelengths, characteristic of STEVE. We propose the presence of threshold conditions required for the SAR arc to evolve into STEVE. In addition, we present parameters such as transition times, luminosities, and arc motion to be applied to ionospheric models.
Spatiotemporal Drought Variation in Midlatitude East Asia Over the Past Half Millennium
Authors: Deng Yang , Gao Linlin , Gou Xiaohua
Published: March 2023

Drought is a recurring challenge, especially in the arid and semi‐arid regions. Therefore, understanding its spatial and temporal variation is important for pre‐disaster planning and sustainable water resource management during drought. However, the sparse and short length of the instrumental records in midlatitude East Asia hampered the full understanding of drought variation, especially at multidecadal and longer timescales. Here, we compiled a tree‐ring network of 364 chronologies in midlatitude East Asia and reconstructed the variation of the averaged May–August Standardized Precipitation Evapotranspiration Index at a spatial resolution of 0.5° × 0.5°, for the period 1501–2000 CE. The reconstruction captured the spatial and temporal variation of actual drought well and has a strong association with a drought atlas that was derived from historical documents. The study area has experienced an expansion of dry areas during the past decades; however, it is still within the natural variability of the past half millennium. According to drought variation during the instrumental period, the study area was divided into four subregions; however, running correlations showed that drought variation in some subregions was similar in past centuries, except in recent decades. This study provides new data for understanding the spatiotemporal variability of drought in midlatitude East Asia, and the vanished correlation between drought variation in some regions during the past decades indicates the complex forcing mechanism of regional drought variation.
Conserving Biodiversity Could Alter Crop Production
Authors: Sidik Saima
Published: March 2023

Researchers examined the land use trade-offs that could come with protecting at-risk species. But some scientists question what should be prioritized.
Successful clearance of persistent SARS-CoV-2 asymptomatic infection following a single dose of Ad5-nCoV vaccine
Authors: Qiu Shaofu , Chen Zhao , Zhu Airu , Zeng Qiuhui , Liu Hongbo , Liu Xiaoqing , Ye Feng , Jin Yingkang , Wu Jie , Yang Chaojie , Wang Qi , Chen Fangli , Chen Lan , Tian Sai , Du Xinying , Hu Qingtao , Cheng Jinling , Chen Canjie , Li Fang , Sun Jing , Wang Yanqun , Zhao Jingxian , Zhao Jincun , Song Hongbin
Published: March 2023

Persistent asymptomatic (PA) SARS-CoV-2 infections have been identified. The immune responses in these patients are unclear, and the development of effective treatments for these patients is needed. Here, we report a cohort of 23 PA cases carrying viral RNA for up to 191 days. PA cases displayed low levels of inflammatory and interferon response, weak antibody response, diminished circulating follicular helper T cells (cTfh), and inadequate specific CD4+ and CD8+ T-cell responses during infection, which is distinct from symptomatic infections and resembling impaired immune activation. Administration of a single dose of Ad5-nCoV vaccine to 10 of these PA cases elicited rapid and robust antibody responses as well as coordinated B-cell and cTfh responses, resulting in successful viral clearance. Vaccine-induced antibodies were able to neutralize various variants of concern and persisted for over 6 months, indicating long-term protection. Therefore, our study provides an insight into the immune status of PA infections and highlights vaccination as a potential treatment for prolonged SARS-CoV-2 infections.
Delayed diagnosis resulting in increased disease burden in multiple myeloma: the legacy of the COVID-19 pandemic
Authors: Carmichael Jonathan , Seymour Frances , McIlroy Graham , Tayabali Sarrah , Amerikanou Rosie , Feyler Sylvia , Popat Rakesh , Pratt Guy , Parrish Christopher , Ashcroft A. John , Jackson Graham H. , Cook Gordon
Published: March 2023

The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients who avoided severe infection, the ramifications of the pandemic have been considerable. The consequences of necessary socio-geographical behavior adaptation, including prolonged shielding and interruptions in delivery of non-pandemic medical services are yet to be fully understood. Using a real-world dataset of 323 consecutive newly diagnosed MM patients in England, we investigated the impact of the COVID-19 pandemic on routes to myeloma diagnosis, disease stage at presentation and relevant clinical outcomes. We demonstrate increasing MM presentations via emergency services and increased rates of bony and extra-medullary disease. Differences were seen in choice of induction therapy and the proportion of eligible patients undertaking autologous stem cell transplantation. Whilst survival was statistically inferior for emergency presentations, significant survival differences have yet to be demonstrated for the entire cohort diagnosed during the pandemic, making extended follow-up critical in this group. This dataset highlights wide-ranging issues facing MM patients consequent of the COVID-19 pandemic, with full impacts for clinicians and policy-makers yet to be elucidated.
Understanding opposing predictions of Prochlorococcus in a changing climate
Authors: Bian Vincent , Cai Merrick , Follett Christopher L.
Published: March 2023

Statistically derived species distribution models (SDMs) are increasingly used to predict ecological changes on a warming planet. ForProchlorococcus, the most abundant phytoplankton, an established statistical prediction conflicts with dynamical models as they predict large, opposite, changes in abundance. We probe the SDM at various spatial-temporal scales, showing that light and temperature fail to explain both temporal fluctuations and sharp spatial transitions. Strong correlations between changes in temperature and population emerge only at very large spatial scales, as transects pass through transitions between regions of high and low abundance. Furthermore, a two-state model based on a temperature threshold matches the original SDM in the surface ocean. We conclude that the original SDM has little power to predict changes whenProchlorococcusis already abundant, which resolves the conflict with dynamical models. Our conclusion suggests that SDMs should prove efficacy across multiple spatial-temporal scales before being trusted in a changing ocean.
Stereoselective C–O silylation and stannylation of alkenyl acetates
Authors: Hu Ying , Peng Jiali , Hu Binjing , Wang Jixin , Jing Jing , Lin Jie , Liu Xingchen , Qi Xiaotian , Li Jie
Published: March 2023

Facile formation of carbon-heteroatom bonds is a long-standing objective in synthetic organic chemistry. However, direct cross-coupling with readily accessible alkenyl acetates via inert C‒O bond-cleavage for the carbon-heteroatom bond construction remains challenging. Here we report a practical preparation of stereoselective tri- and tetrasubstituted alkenyl silanes and stannanes by performing cobalt-catalyzed C‒O silylation and stannylation of alkenyl acetates using silylzinc pivalate and stannylzinc chloride as the nucleophiles. This protocol features a complete control of chemoselectivity, stereoselectivity, as well as excellent functional group compatibility. The resulting alkenyl silanes and stannanes show high reactivities in arylation and alkenylation by Hiyama and Stille reactions. The synthetic utility is further illustrated by the facile late-stage modifications of natural products and drug-like molecules. Mechanistic studies suggest that the reaction might involve a chelation-assisted oxidative insertion of cobalt species to C‒O bond. We anticipate that our findings should prove instrumental for potential applications of this technology to organic syntheses and drug discoveries in medicinal chemistry.
High interspecific competitiveness of the invasive plant Xanthium italicum Moretti severely reduces the yield and quality of Carthamus tinctorius L.
Authors: Ma Xia , Hou Mingcai , Ma Miao
Published: March 2023

Safflower is an annual herb of Compositae, which has great economic value. To explore the impact of invasive weedXanthium italicumMoretti on the economic crop safflower, field experiments were conducted, the growth-related characters and the relative intensity of competition between the two species was explored. The results showed that under monoculture conditions, the stem height, crown width, stem diameter and the biomass ofX. italicumroot, stem and leaves were 1.14, 1.96, 1.82, 4.42, 4.21 and 3.99 times as high as those of safflower, respectively. When the two species coexisted, the growth related characters ofX. italicumwere further significantly improved, while the growth related characters of safflower were significantly decreased. When coexisted withX. italicum, the corolla biomass, hydroxysafflor yellow A content of corolla, seed yields, 100-seed weight, and seed oil content of safflower in the interplanted treatment 90.04%, 33.11%, 63.89%, 40.58%, and 25.61% lower than those in the monocultured treatment, respectively. Relative yield (RY) and Competitive balance index (CB) ofX. italicumand safflower showed that the interspecific competitiveness ofX. italicumwas significantly higher than that of safflower. Under the competitive inhibition ofX. italicum,not only the vegetative growth, but also the reproductive growth, yield, and quality of the economic organs of safflower were significantly negatively impacted. Together, our findings provide important scientific basis for evaluating the invasion risks and consequences of safflower’s cropland ecosystem byX. italicum.
αSiC - βSiC - graphene composites
Authors: Razmjoo Ali , Baharvandi Hamid Reza , Ehsani Nasser
Published: March 2023

In this study, the mechanical properties of the pressureless sintered samples of α-SiC based composite containing 0–3 wt.% graphene and 0–15 wt.% nano β-SiC were investigated. Simultaneous usage of nano β-SiC and graphene and transformation of β-SiC (3C) to α-SiC (6H/4H) resulted in elongation of secondary α-SiC grains, which significantly improved the mechanical properties (e.g. fracture toughness) of SiC ceramics. According to the results, the highest Relative density of 99.04%, Young’s modulus of 537.76 GPa and fracture toughness of 5.73 MPa × m1/2 were obtained in the sample containing 5 wt.% nano β-SiC and 1 wt.% graphene (5B1G). In addition, two methods of measuring bending strength including three-point bending tests and biaxial tests (piston-on-three-ball) were compared. Strip-shaped specimens were prepared for three-point bending test and disc-shaped specimens were prepared for biaxial bending test. Each bending test was evaluated using a universal testing machine. The results showed that the biaxial bending strength is less than the three-point bending strength. Also, the maximum three-point bending strength of 582.01 MPa and biaxial bending of 441.56 MPa were obtained in 5 wt.% Nano β-SiC and 1 wt.% Graphene samples (5B1G). Studies have shown that in addition to the many advantages of using the biaxial bending method, the results have a very similar trend to the three-point bending strength. Also, the most-increased hardnesses of 28.03 GPa and 29.97 GPa were seen in the sample containing 5 wt.% nano β-SiC (5B) with forces of 10 N and 1 N, respectively. One of the effective mechanisms in improving the fracture toughness of α-SiC ceramics is crack deflection/bridging. Also, the difference in thermal expansion of the α-SiC matrix and the reinforcements, leading to the creation of residual stresses between the matrix grains and the reinforcement, is effective in improving the mechanical properties (e.g. strength and fracture toughness).
Tunable growth of one-dimensional graphitic materials: graphene nanoribbons, carbon nanotubes, and nanoribbon/nanotube junctions
Authors: Lou Shuo , Lyu Bosai , Chen Jiajun , Qiu Lu , Ma Saiqun , Shen Peiyue , Zhang Zhichun , Xie Yufeng , Liang Qi , Watanabe Kenji , Taniguchi Takashi , Ding Feng , Shi Zhiwen
Published: March 2023

Graphene nanoribbons (GNRs) and carbon nanotubes (CNTs), two representative one-dimensional (1D) graphitic materials, have attracted tremendous research interests due to their promising applications for future high-performance nanoelectronics. Although various methods have been developed for fabrication of GNRs or CNTs, a unified method allowing controllable synthesis of both of them, as well as their heterojunctions, which could largely benefit their nano-electronic applications, is still lacking. Here, we report on a generic growth of 1D carbon using nanoparticles catalyzed chemical vapor deposition (CVD) on atomically flat hexagonal boron nitride (h-BN) substrates. Relative ratio of the yielded GNRs and CNTs is able to be arbitrarily tuned by varying the growth temperature or feeding gas pressures. The tunability of the generic growth is quantitatively explained by a competing nucleation theory: nucleation into either GNRs or CNTs by the catalysts is determined by the free energy of their formation, which is controlled by the growth conditions. Under the guidance of the theory, we further realized growth of GNR/CNT intramolecular junctions through changing H2 partial pressure during a single growth process. Our study provides not only a universal and controllable method for growing 1D carbon nanostructures, but also a deep understanding of their growth mechanism, which would largely benefit future carbon-based electronics and optoelectronics.
Live-cell photoactivated localization microscopy correlates nanoscale ryanodine receptor configuration to calcium sparks in cardiomyocytes
Authors: Hou Yufeng , Laasmaa Martin , Li Jia , Shen Xin , Manfra Ornella , Nordén Einar S. , Le Christopher , Zhang Lili , Sjaastad Ivar , Jones Peter P. , Soeller Christian , Louch William E.
Published: March 2023

Ca2+ sparks constitute the fundamental units of Ca2+ release in cardiomyocytes. Here we investigate how ryanodine receptors (RyRs) collectively generate these events by employing a transgenic mouse with a photoactivated label on RyR2. This allowed correlative imaging of RyR localization, by super-resolution photoactivated localization microscopy, and Ca2+ sparks, by high-speed imaging. Two populations of Ca2+ sparks were observed: stationary events and ‘traveling’ events that spread between neighboring RyR clusters. Traveling sparks exhibited up to eight distinct releases, sourced from local or distal junctional sarcoplasmic reticulum. Quantitative analyses showed that sparks may be triggered by any number of RyRs within a cluster, and that acute β-adrenergic stimulation augments intracluster RyR recruitment to generate larger events. In contrast, RyR ‘dispersion’ during heart failure facilitates the generation of traveling sparks. Thus, RyRs cooperatively generate Ca2+ sparks in a complex, malleable fashion, and channel organization regulates the propensity for local propagation of Ca2+ release.
Advances in nanomedicine for the treatment of infectious diseases caused by viruses
Authors: Dash Somya Ranjan , Kundu Chanakya Nath
Published: March 2023

An efficient anti-viral therapy strategy based on nanomedicine.
Using generative adversarial networks to match experimental and simulated inelastic neutron scattering data
Authors: Anker Andy S. , Butler Keith T. , Le Manh Duc , Perring Toby G. , Thiyagalingam Jeyan
Published: March 2023

Exp2SimGAN is an unsupervised image-to-image machine learning model that converts simulated data into experimental-like data, and vice versa.
Preparation of synbiotic milk powder and its effect on calcium absorption and the bone microstructure in calcium deficient mice
Authors: Jia Mingjie , Luo Jiayuan , Gao Bo , Huangfu Yunpeng , Bao Yihong , Li Dehai , Jiang Shilong
Published: March 2023

Synbiotic milk powder improves the bone state of calcium-deficient mice.
Antiviral activity of amide-appended α-hydroxytropolones against herpes simplex virus-1 and -2
Authors: Gazquez Casals Andreu , Berkowitz Alex J. , Yu Alice J. , Waters Hope E. , Schiavone Daniel V. , Kapkayeva Diana M. , Morrison Lynda A. , Murelli Ryan P.
Published: March 2023

Amide-appended α-hydroxytropolones from a previously described library suppressed herpes simplex virus (HSV) replication in cell culture. A targeted follow-up library led to potent analogs against HSV-1 and -2, including acyclovir-resistant mutants.
Modification of micro/nanoscaled manganese dioxide-based materials and their electrocatalytic applications toward oxygen evolution reaction
Authors: He Gaihua , Liao Ye
Published: March 2023

The MnO2 OER electrocatalysts is modified by morphology control, structure construction, facet engineering, doping and heterojunctions, whose mechanisms and practical applications are summarized to develope efficient OER electrocatalysts.
Osteogenic and long-term antibacterial properties of Sr/Ag-containing TiO2 microporous coating in vitro and in vivo
Authors: Wang Huan , Zheng Tian-Xia , Yang Nuo-Ya , Li Ying , Sun Hong , Dong Wei , Feng Li-Fang , Deng Jiu-Peng , Qi Meng-Chun
Published: March 2023

Bacterial infection and poor osseointegration are two critical issues that need to be solved for long-term use of titanium implants.
Impact of iron oxide nanoparticles on a lead-polluted water–soil–plant system under alternating periods of water stress
Authors: Mounier Léa , Pédrot Mathieu , Bouhnik-Le-Coz Martine , Cabello-Hurtado Francisco
Published: March 2023

Iron oxide nanoparticles (IONPs) are promising materials for the remediation of trace elements, which are a significant source of soil pollution.
Zn–Sr-sintered true bone ceramics enhance bone repair and regeneration
Authors: Hu Yingkun , Wang Yi , Feng Qinyu , Chen Tianhong , Hao Zhuowen , Zhang Shuwei , Cai Lin , Guo Xiaodong , Li Jingfeng
Published: March 2023

Schematic of Zn–Sr-TBC for bone repair. Zn–Sr-TBC promotes the proliferation, differentiation, and adhesion of BMSCs on the scaffold. Zn–Sr-TBC has antibacterial activity. Scaffolds promote the repair of bone defects in rats.
LiCs3AlB7O14: achieving enhanced optical anisotropyvia[AlO4] tetrahedron introduction to rearrange the anionic framework
Authors: Li Xingqi , Chu Dongdong , Qiu Haotian , Wu Yabo , Hou Xueling
Published: March 2023

Herein, by introducing [AlO4] tetrahedra, a new aluminoborate was discovered. This work confirms that the introduction of [AlO4] tetrahedra can lead to the rearrangement of anionic framework of borate system and thereby enhance the birefringence.
Mechanistic insight into Pb2+ and Hg2+ ion sensing using cobalt-based coordination polymer in aqueous phase
Authors: Nath Akashdeep , Gaikwad Diti Vikram , Mandal Sukhendu
Published: March 2023

An emissive cobalt-coordination polymer was used for highly sensitive lead(ii) ion sensing in water attributed to excited-state interaction, and comparatively lower mercury(ii) ion sensing due to both ground- and excited-state interaction.
Origin, exposure routes and xenobiotics impart nanoplastics with toxic effects on freshwater bivalves
Authors: Arini Adeline , Muller Sandra , Coma Véronique , Grau Etienne , Sandre Olivier , Baudrimont Magalie
Published: March 2023

Gene expression was more disrupted in the case of diet-borne exposure of bivalves to NP-L (from the Leyre River) compared to NP-PS, accompanied by neurotoxic effects, synergistic effects with aluminium, and this, even after 7 days of depuration.
Transcriptomics integrated with metabolomics reveals the ameliorating effect of mussel-derived plasmalogens on high-fat diet-induced hyperlipidemia in zebrafish
Authors: Feng Junli , Chen Xi , Wang Shitong , Zhang Jian , Wang Qingcheng , Guo Shunyuan , Shen Qing
Published: March 2023

Mussel-derived plasmalogens has a protective effect against HFD-induced hyperlipidemia. The gene-metabolite network related to the effects of Pls has been explored through the integrated analysis of hepatic transcriptome and metabolome.
Gold-catalyzed endo-selective cyclization of alkynylcyclobutanecarboxamides: synthesis of cyclobutane-fused dihydropyridones
Authors: Garre M. Soledad , Otárola Guillermo G. , Merino Estíbaliz , Sucunza David , Aguilar Enrique , Quirós M. Teresa , Vaquero Juan J. , García-García Patricia
Published: March 2023

Gold-catalyzed cyclizations of alkynylcyclobutanes having an amide group proceed selectively through an endo-cyclization, providing an efficient methodology for the synthesis of cyclobutane-fused dihydropyridones.
Squaramides for colorimetric and fluorescent anion sensing
Authors: Lane Jakob D. E. , Jolliffe Katrina A.
Published: March 2023

Simple squaramides bearing two fluorophores provide either colourimetric or fluorescent responses to oxoanions. Insertion of a methylene spacer between the fluorophore and squaramide leads to a ratiometirc fluorescent response to anions.
Aminophthalimide as a mimetic of purines and a fluorescent RNA base surrogate for RNA imaging
Authors: Lang Fabian , Rönicke Franziska , Wagenknecht Hans-Achim
Published: March 2023

Aminophthalimide and N,N-dimethylaminophthalimide are used as fluorescent mimetics of purines due to their similar size and their possibility for hydrogen bonding.
Fluorescent sensing of non-steroidal anti-inflammatory drugs naproxen and ketoprofen by dansylated squaramide-based receptors
Authors: Picci Giacomo , Aragoni M. Carla , Arca Massimiliano , Caltagirone Claudia , Formica Mauro , Fusi Vieri , Giorgi Luca , Ingargiola Filippo , Lippolis Vito , Macedi Eleonora , Mancini Luca , Mummolo Liviana , Prodi Luca
Published: March 2023

Bis-squaramide receptors L1–L4 bearing a dansyl moiety were considered as fluorescent probes for non steroidal antinflamatory drugs naproxene and ketoprofen.
Block–random copolymer stabilisers for semi-batch emulsion polymerisation
Authors: Werner Arthur , Sanders Connor A. , Smeltzer Sandra E. , George Sean R. , Gernandt Andreas , Reck Bernd , Cunningham Michael F.
Published: March 2023

Polystyrene-b-[polystyrene-r-poly(acrylic acid)] block–random copolymers are efficient stabilisers in semi-batch emulsion polymerisations, yielding high-solids latexes with low viscosity.
Colloidal synthesis of hexagonal CuFe(SxSe1−x)2 nanoplates with exposed highly active (220) facets for boosting overall water splitting
Authors: Huang Shoushuang , Cong Xiansheng , Ye Tong , Liu Libin , Peng Kaimei , Zhang Lingchao , Bao Jinmei , Gao Pengyan , Chen Qiaochuan , He Qingquan
Published: March 2023

CuFe(SxSe1−x)2 NPs with adjusted S/Se ratios were synthesized via a hot-injection method, which exhibited excellent electrocatalytic activities for water splitting due to the reduced band gap, regulated d-band center, and high exposure of active (220) facets.
Petal-like Mn-doped α-Ni(OH)2 nanosheets for high-performance Li–S cathode material
Authors: Zhao Changfeng , Liu Hanyang , Liu Jiawei , Shi Yanhong , Wang Shuguang , Tang Qiwei , Zhu Xiangbing , Zhang Huimin , Zhao Yan
Published: March 2023

Lithium–sulphur (Li–S) batteries are high-energy-density and cost-effective batteries.
Three new coordination geometries of homoleptic Zn complexes of curcuminoids and their high antiproliferative potential
Authors: Meza-Morales William , Alvarez-Ricardo Yair , Obregón-Mendoza Marco A. , Arenaza-Corona Antonino , Ramírez-Apan María Teresa , Toscano Rubén A. , Poveda-Jaramillo Juan Carlos , Enríquez Raúl G.
Published: March 2023

We add herein three new geometries of homoleptic type complexes i.e. octahedral, trigonal-pyramidal, and trigonal-bipyramidal. Moreover, the IC50 values for the DiMeOC-Zn complex were 8 or 22 times higher than cisplatin in the U251 and HCT15 cell lines.
Unveiling the effect of crystallinity and particle size of biogenic Ag/ZnO nanocomposites on the electrochemical sensing performance of carbaryl detection in agricultural products
Authors: Le Nhat Trang Nguyen , Thi Nguyet Nga Dao , Tufa Lemma Teshome , Tran Van Tan , Hung Thuan-Tran , Ngoc Phan Vu , Pham Tuyet Nhung , Hoang Van-Tuan , Le Anh-Tuan
Published: March 2023

We have investigated the green synthesis of Ag/ZnO nanocomposites via a microwave-assisted/biogenic electrochemical method with mangosteen peel extract. Ag/ZnO-based sensing platform has been proposed for carbaryl detection in agriculture products.
Investigating the role of phonons in the phase stability of uranium-based Laves phases
Authors: Nykwest Erik , Shields Ashley E. , Brubaker Z. E. , Niedziela J. L. , Isbill S. B. , Miskowiec Andrew
Published: March 2023

DFT investigations of the thermodynamic stability of UCo2 and UNi2 for three Laves phase structure types were extrapolated to UCo2xNi2(1−x).
Enhanced charge storage capacity and high rate capabilities of Ni2Co-layered double hydroxides/expanded-graphite composites as anodes for Li-ion batteries
Authors: Chandra Sahoo Ramesh , Moolayadukkam Sreejesh , Seok Jun Ho , Lee Sang Uck , Matte H. S. S. Ramakrishna
Published: March 2023

The expanded graphite has been used as a matrix to grow Ni2Co-LDH and this enabled to obtain stability and fast charging capabilities when used as anode for Li-ion batteries. The experimental findings are supported by DFT calculations.
Mg-Ag-Sb thin films produced by solid-state reactive diffusion
Authors: Oueldna Nouredine , Portavoce Alain , Kammouni Abdelkhalek , Hoummada Khalid
Published: March 2023

α-MgAgSb is a tellurium-free thermoelectric material that exhibits good thermoelectric properties near room temperature. Being made of relatively abundant elements compatible with the complementary metal oxide semiconductor (CMOS) technology, it is considered as a possible solution for the development of high-efficiency thermoelectric devices for heat waste harvesting in microelectronic setups. This study presents a first attempt to investigate the structural properties of MgAgSb thin films prepared by solid-state reactive diffusion. X-ray diffraction (XRD) was used to follow phase formation in thin films, first, in the case of the binary Ag3Sb and Mg3Sb2 compounds, and then, in the case of the ternary system Mg-Ag-Sb. For the later, in situ XRD was used to follow real-time phase formations during the reaction of the bilayerAg3Sb/Mg3Sb2. The results show that the phase α-MgAgSb can be produced by reactive diffusion at the interface of the bilayer. Furthermore, the three phases α, β, and γ are shown to coexist at 360 °C, which can be the result of the thin film geometry (surface and interface effects) or due to a different stoichiometry between these three phases contrasting with usual belief. At temperatures higher than 450 °C, γ-MgAgSb is the only phase stabilized in the film. This study serves as a benchmark for the production of pure α-MgAgSb thermoelectric thin films by reactive diffusion.
Laserix : Une plate-forme pour le développement large spectre d’applications de la lumière intense
Authors: Baynard Elsa , Cassou Kevin , Drobniak Pierre , Demailly Julien , Guilbaud Olivier , Kraych Adrien , Lucas Bruno , Maillet Max , Pandey Alok Kumar , Pittman Moana , Ros David , Sarazin Xavier , Sanson Fabrice , Kazamias Sophie
Published: March 2023

LASERIX est une plateforme de l’IJClab sur le campus de l’Université Paris Saclay. Le laser est une chaîne CPA de niveau 50 TW à 10 Hz. Des thématiques de recherche en rapport avec la physique des deux infinis sont menées en parallèle avec une vocation affirmée d’ouverture à la formation. Nous présentons un panorama sur les sources XUV de lumière structurée, l’accélération laser plasma et des études prospectives sur l’étude des propriétés du vide soumis à un champ électromagnétique ultra-intense.
Acheter une prestation de procédés laser
Authors: Verdier Emma , Faucon Marc
Published: March 2023

Le développement des études de l’interaction laser/matériau allié aux progrès technologiques croissants des fournisseurs de sources laser ainsi que des éléments constituant les systèmes d’usinage permettent depuis plusieurs dizaines d’années d’accompagner industriels et enseignants chercheurs dans l’intégration de procédés laser pour leurs activités de sous-traitance ou de recherche développement et innovation.
A probabilistic point of view for the Kolmogorov hypoelliptic equations
Authors: Etoré P. , León J. R. , Prieur C.
Published: March 2023

In this work, we propose a method for solving Kolmogorov hypoelliptic equations based on Fourier transform and Feynman–Kac formula. We first explain how the Feynman–Kac formula can be used to compute the fundamental solution to parabolic equations with linear or quadratic potential. Then applying these results after a Fourier transform we deduce the computation of the solution to a first class of Kolmogorov hypoelliptic equations. Then we solve partial differential equations obtained via Feynman–Kac formula from the Ornstein–Uhlenbeck generator. Also, a new small time approximation of the solution to a certain class of Kolmogorov hypoelliptic equations is provided. We finally present the results of numerical experiments to check the practical efficiency of this approximation.
Auf geht’s ins Neue Jahr!
Authors: Knabl Michaela
Published: March 2023

Die Radiopraxis hat sich als großartiges Medium für
Radiologietechnologie im deutschsprachigen Raum erwiesen. Es bietet seit 2008 viele
Möglichkeiten der nachweisbaren Fortbildung durch dieses spezielle
Literaturstudium, aber auch Austausch und Information über neueste
Entwicklungen.
Patientenkommunikation im Berufsalltag
Authors: Huber Evelyn
Published: March 2023

Dieser Artikel beleuchtet das Thema Kommunikation aus unterschiedlichen
Perspektiven, zeigt, wie wichtig neben dem gesprochenen Wort
Körpersprache und Stimme sind, welchen (kommunikativen)
Herausforderungen sich unsere Berufsgruppe alltäglich stellen muss und
wie Patientenkommunikation erfolgreich gelingen kann.
Workflow Improvement of Electronic Health Record Usage in a Tertiary Pediatric Burns Clinic
Authors: Tanny Sharman P. Tan , Hsu Rebecca P. , Teague Warwick J. , Truong Diana , Cheng Daryl R.
Published: March 2023

Background As a high patient-throughput clinic, the Royal Children's Hospital's multidisciplinary burns clinic's efficiency of clinic workflow and streamlined patient assessment is crucial. The clinic has been using a customized “burns assessment tool” (BAT) as part of its integrated electronic health record (EHR) since 2016.

Objectives The aim was to assess the usage patterns of the BAT at baseline, followed by re-evaluation following interventions to improve efficiency and utilization of the BAT.

Methods This study was a prospective observational time–motion quality improvement study. Observations of 19 clinicians in the pediatric burns clinic by five trained observers using a validated time–motion capture tool (TimeCaT 3.9) to map clinician workflow, with specific reference to time spent on a list of predetermined tasks, were conducted. Baseline data were collected for 7 weeks followed by three cycles of interventions and observations over 5 months.

Results At baseline, the median time for a patient visit was 24.56 minutes (range: 2.78–73.72 minutes, interquartile range: 14.17–27 minutes), with most of the time spent on documentation (34.6%) and patient contact tasks (26.0%). In each of the study cycles, the median time spent on documentation within the EHR was significantly reduced compared with baseline (cycle 1 29.8%, p = 0.08; cycle 2 20.4%, p ≤ 0.01; cycle 3 27.32%, p = 0.04). The time spent on patient contact increased when comparing baseline to data of cycles 1, 2, and 3 (25.96 vs. 33.27% of visit, p = 0.04). There was no significant change in absolute time spent on the BAT during the study.

Conclusion The study findings of clear, significant, and sustained improvement in documentation efficiency and the corresponding increase in patient contact time after interventions were introduced reinforce the importance of integration of an EHR with clinical workflow.
Therapeutic Potency of Mono- and Diprenylated Acetophenones: A Case Study of In-Vivo Antimalarial Evaluation
Authors: Yahya Muhammad H. , Babalola Sodeeq A. , Idris Abdullahi Y. , Hamza Asmau N. , Igie Nosakhare , Odeyemi Isaiah , Musa Aliyu M. , Olorukooba Amina B.
Published: March 2023

Malaria remains a febrile infection of public health concern in many countries especially tropical countries in Africa and certain countries in Southern and North America such as Brazil, Costa Rica, Mexico, Dominican Republic, Colombia, and Ecuador. Hence this has made research into this area paramount. Acetophenones are active fragments in many compounds with promising antimalarial activity, such as chalcones. The aim of the present study was to investigate antimalarial activity of 3,5-diprenyl acetophenone (I) and 5-diprenyl acetophenone (II) in in vivo. In this study, compounds I and II were synthesized using an aromatic substitution reaction. The in-vivo antimalarial potential of compounds I and II was analyzed in Plasmodium berghei-infected mice. Our data showed that compound I (25, 50, and 100 mg/kg) had promising antimalarial activity, with parasitemia inhibited rate being 68.03, 65.16, and 69.75%, respectively. Compound II dose-dependently inhibited parasitemia levels, it demonstrated an infinitesimally higher activity (72.12%) when compared with compound I (69.75%) at 100 mg/kg dose. The two compounds passed the rule of three, Lipinski's rule of five, predicted plausible pharmacokinetic profile (ADME), and apparent safety profile, and demonstrated drug-like fragments. The study provided guidance in exploring novel antimalarial compounds based on the scaffolds of prenylated acetophenones.
Pneumothorax after CT-Guided Lung Biopsy: What Next?
Authors: Shera Faiz Altaf , Shera Tahleel Altaf , Shah Omair Ashraf , Robbani Irfan , Choh Naseer Ahmad , Shaheen Feroze , Gojawari Tariq Ahmad
Published: March 2023

Background Pneumothorax is the most common complication of computed tomography (CT)-guided lung biopsy. The asymptomatic rate ranges from 17.5 to 72%. The symptomatic rate requiring chest tube insertion is 6 to 18%.

Aims This article studies the role of management of postbiopsy pneumothoraces by needle aspiration and pigtail catheter insertion.

Methods This was a prospective observational study conducted over 2 years. Postbiopsy and prior to withdrawing the coaxial cannula a CT data set was obtained to detect and quantify pneumothoraces as mild, moderate, and severe. In all asymptomatic cases of mild pneumothorax simple observation was done. In all asymptomatic cases of moderate pneumothorax, immediate needle aspiration was performed. In all symptomatic cases, cases with severe pneumothorax, and cases with progressively enlarging pneumothorax small caliber 6 to 8F pigtail catheters were inserted.

Results Ninety-one cases had mild pneumothorax, 42 had moderate pneumothorax, and 18 had severe pneumothorax. In the 91 patients of mild pneumothorax only 1 (1%) patient showed increase in size of pneumothorax on follow-up requiring catheter insertion. In the 42 cases of moderate pneumothorax, which were managed by simple aspiration of pneumothorax, 4 (9.5%) cases showed increase in size of pneumothorax on follow-up. A total 23 cases required pigtail catheter insertion in our study. These constituted 15.2% of pneumothorax cases. The mean duration of catheterization in our study was 3.74 ± 1.09 days.

Conclusion Majority of pneumothoraces are benign and do not require any intervention, just observation. Manual aspiration is an effective way of treating moderate pneumothoraces with success rate of 90%, thereby reducing the number of cases requiring catheter insertion; however, close observation is required as few cases may progress to severe pneumothorax and require pigtail insertion. Only a small percentage of biopsy cases (6.4%) require catheter insertion which is a safe and effective treatment.
The ion equation of state of plasmas in the warm dense matter regime
Authors: Petrov George M. , Davidson Asher D.
Published: March 2023

The existing “quotidian equation of state (QEOS)” model [More et al., Phys. Fluids 31, 3059 (1988)] has been revised, and an alternative set of formulas is provided for the Helmholtz free energy, internal energy, heat capacity, and pressure. A novel scheme for constructing the ion equation-of-state is proposed based on the additive of solid and fluid components that act throughout the temperature range, in contrast to the QEOS that matches the thermodynamic parameters at selected interfaces. These components are continuous along with their first and second derivatives and obey limiting cases and thermodynamics laws (Lindemann melting, Dulong–Petit law, Grüneisen pressure law, and ideal gas law). Thus, the new scheme eliminates discontinuities in thermodynamics parameters across interfaces and ensures that the thermodynamics parameters are consistent with each other. The Helmholtz free energy, internal energy, heat capacity, and pressure have been approximated with computationally efficient formulas that can be used as parts of other models, e.g., hydro-simulations.
Nanolamellar phase transition in an additively manufactured eutectic high-entropy alloy under high pressures
Authors: Pope Andrew D. , Iwan Seth , Clay Matthew P. , Vohra Yogesh K. , Katagiri Kento , Dresselhaus-Marais Leora , Ren Jie , Chen Wen
Published: March 2023

Much is unknown about how phase transitions link to micro-/nano-structures in high-entropy systems, especially under extreme pressure and temperature conditions. This work studies the evolution of dual-phase nanolamellar eutectic high-entropy alloy phases of AlCoCrFeNi2.1 generated by laser powder-bed fusion (L-PBF) for pressures up to 42 GPa. We compare quasi-hydrostatic high pressure synchrotron x-ray diffraction studies on L-PBF printed cylindrical samples up to 5.5 GPa (large-volume Paris–Edinburgh cell) to those carried out on an L-PBF printed foil in a diamond anvil cell where the pressure reached 42 GPa. Our results show that the initially alternating face-centered cubic (FCC) and body-centered cubic (BCC) nanolamellar structure of AlCoCrFeNi2.1 transformed into single-phase FCC nanolamellae under high pressure with BCC–FCC phase transformation completion at 21 ± 3 GPa. Our results indicate a diffusionless BCC–FCC transformation in this additively manufactured far-from-equilibrium microstructure and demonstrate that the FCC phase is stable up to very high pressures. The measured equation of state for the FCC phase of AlCoCrFeNi2.1 is presented up to 42 GPa and shows excellent agreement between the data obtained in large-volume press and diamond anvil cell experiments.
Effect of aging treatment on properties of Al–Si alloy solidified at high-pressure
Authors: Huang Haosheng , Jiang Bo , Jiang Wentao , Wang Ye , Zhu Dongdong , Hu Maoliang
Published: March 2023

The thermal conductivity and microhardness of the high-pressure solidified Al–Si-Fe-Mg alloys can be significantly improved by a large number of solute atoms precipitated and hence released the lattice distortion after aging for 12 h. And the α-Al lattice constant does not change significantly during the aging treatment from 12 h to 24 h, indicating the alloy released less lattice distortion. The interface between the precipitated phase and the α-Al matrix gradually evolved into an incoherent relationship with the extension of aging time, which has a greater hindering effect on the thermal conductivity of the alloy, and the amount of precipitated phase will be the primary factor in decreasing the thermal conductivity of the alloy at this point.