bluuebunny/crossref_metadata_2025 huggingface dataset:
EXFOLIATING THE PETALS OF OBESITY PATHOLOGY: FROM PATHOGENESIS TO EMERGING DRUG TARGETS
Authors: Nayak Nikita , Kumari Shivangi , Mukherjee Tuhin , Mohanty Satyajit
Published: June 2024

This is a comprehensive book chapter that delves into the multifaceted aspects of obesity, exploring its pathogenesis and emerging drug targets. A detail outline of the prevalence and health ramifications of obesity sets a stage for the subsequent discussions. Genetic and other factors in obesity are examined in detail, emphasizing the role of genetic predisposition and the impact of environmental factors such as diet, immobile lifestyle, and socioeconomic influences. The chapter then shifts focus to the fat tissue, highlighting its role as an endocrine organ and exploring the relationship between adipose tissue inflammation and metabolic dysfunction associated with obesity. The impact of gut microbiota on metabolism is explored, with an overview of gut dysbiosis and its association with obesity. Potential mechanisms linking gut microbiota to weight regulation are examined, shedding light on the interplay between the microbiome and obesity. The chapter delves into the central nervous system's regulation of energy homeostasis, providing an overview of the hypothalamus and its role in appetite regulation, with a specific focus on the leptin-melanocortin pathway and its implications in obesity pathogenesis. Epigenetic modifications associated with obesity and their impact on metabolic processes are explored. The role of neurotransmitters, such as dopamine and serotonin, in appetite regulation and reward pathways are discussed. The latter part of the chapter focuses on emerging drug targets for obesity treatment and it gives an overview of current pharmacological approaches and discusses recent research on novel drug targets and therapeutic strategies.
A NARRATIVE OVERVIEW ON CRUCIAL ROLE OF GUT MICROBES IN CHRONIC INFECTIOUS AND INFLAMMATORY DISEASES
Authors: Chatterjee Prity , Dey Riya , Kumari Shweta , Mukherjee Shreetama , Chowdhury Sumana Roy , Adhikary Krishnendu
Published: June 2024

Numerous microorganisms in the human gut microbiota fight pathogens in infectious diseases and suppress or induce inflammation in various immunological situations. A significant microbial community that is vital to human existence is the human gut microbiome. It promotes the proliferation, development, and differentiation of epithelial and immunological cells, which aids in maintaining intestinal homeostasis. Disorders that affect the microbiota induce an imbalance in the host’s & #39; immunological regulation. Research analysis suggests that the gut microbial ecology is linked to the onset and increment of several infectious and inflammatory disorders. Understanding the connection between gut microbiota and control of the immune system is therefore critical for understanding the mechanisms involved in various illnesses. The review focuses on the main gut bacteria capable of influencing the immune response in various pathologies, as well as a possible target for disease prevention and treatment due to the control and mechanism of GM on gastrointestinal, metabolic, and neurological diseases.
FUTURISTIC TRENDS IN BRAIN TUMOR REHABILITATION: UNLEASHING THE MULTIDISCIPLINARY APPROACHES OF PHYSIOTHERAPY
Authors: Chhabra Charu , Ahmad Khan Dr. Sohrab , Kaur Harsirjan , Aziz Rabia
Published: June 2024

Brain tumors prevalence is roughly 2% of all malignancy cases worldwide. An intracranial tumor is an anomalous proliferation of cells of the brain. Brain tumors, whether primary or metastatic, benign or malignant, have significant implications for patients, relatives, & the health-care system. They can cause a range of physical, sensory, intellectual, psychological, and social issues, which can severely affect a person's quality of life. Adaptability and regular evaluation are essential to dealing with patients' fluctuating functional alterations in neuro-oncological diagnoses. Therefore, the physical therapist should give thought to various factors while delivering rehabilitation therapy to an elderly patient with a neuro-oncological diagnosis. Evidence-based physiotherapy interventions for managing symptoms and improving the quality of life of brain tumor patients, highlights the role of exercise programs in preserving cardiovascular endurance, muscular strength, and function. Physical activity effectively addresses fatigue in cancer patients. The use of aerobic and resistance training is recommended, although specific instructions regarding timing, dose, and intensity are not provided. The management of gait impairments, cognitive impairments, depression and anxiety, social isolation, and the role of occupational therapy in brain tumor rehabilitation must be addressed for the patients with brain tumor. A multidisciplinary approach, including occupational therapy techniques, neuro-developmental therapy, proprioceptive neuromuscular facilitation techniques, and conventional therapy programs is the key. Additionally, the use of vibration therapy for patients with gliomas in the acute phase of rehabilitation. It suggests that vibration therapy, specifically applied to the cervical region, can improve functional outcomes, daily living activities, mobility, and cognition. A multidisciplinary approach and evidence-based physiotherapy interventions in the rehabilitation of brain tumor patients is of immense importance. Thorough assessment, individualized treatment plans, and regular evaluation to address the specific needs and challenges faced by these patients.
FUTURE TRENDS OF AI IN FOOD SCIENCE & TECHNOLOGY AND AGRICULTURE
Authors: Gunjal Rahul Dnyanesh , Sheetal Sonawdekar Dr.
Published: June 2024

Artificial Intelligence (AI) falls under the domain of computer science and aims to replicate human cognitive processes, learning abilities, and knowledge retention. AI can be categorized into strong AI and weak AI. Weak AI focuses on creating machines that imitate human intelligence and judgment, while strong AI asserts that machines can replicate human thought processes. A variety of sectors, including gaming, weather prediction, heavy industry, process industry, food production, medicine, data analysis, stem cell research, and knowledge representation, have adopted AI techniques for their specific purposes. AI encompasses a diverse range of algorithms like Support Vector Machine (SVM), K-nearest neighbour (KNN), Random Forest, Reinforcement Learning, and Artificial Neural Network (ANN), among others. AI's impressive performance has made it increasingly popular in various industries, particularly for decision-making and process estimation, with the main objectives of cost reduction, improved quality, and enhanced profitability.
THE BENEFICIAL ROLE OF LACTO-FERMENTED VEGETABLE FOOD KIMCHI: A REVIEW
Authors: Anar Lumsela C , Sharma Dhananjay
Published: June 2024

Kimchi is a fermented vegetable dish prepared from vegetables, usually Chinese cabbage, and a variety of seasonings. Due to its distinctive flavor, nutritional advantages, and potential health-promoting properties, it has gained worldwide acclaim. This review will highlight the beneficial role of kimchi in human health. Kimchi is a rich source of probiotics which are beneficial bacteria that promote gut health. Lactobacillus and Bifidobacterium are two kinds of lactic corrosive microorganisms that are delivered during the maturation cycle used to make kimchi. The gut microbiota's composition could be improved and digestive health could be supported by these bacteria. The probiotics are found to boost immune system function, reduce the risk of gastrointestinal tract disorders, and improve bowel movements. Kimchi is also packed with multiple types of minerals and vitamins such as vitamin C, calcium and vitamin K which are essential for overall health. As we all know vitamin C is known for its antioxidant properties which help boost the immune system and protect against oxidative stress. Calcium is necessary for healthy teeth and bones, and vitamin K is necessary for blood and bone coagulation. Additionally, carotenoids and flavonoids, phytonutrients with antioxidant and anti-inflammatory properties, can be found in kimchi. These phytonutrients have been linked with lower chances of chronic diseases such as cardiovascular due to their ability to neutralize harmful free radicals and modulate inflammation. It is low in calories and fat and the fermentation process enhances the bioavailability of nutrient-dense food. Its probiotic content supports gut health while its vitamins, minerals, and phytonutrients contribute to overall well-being. Fiber content in kimchi promotes satiety, reduces appetite, and regulates blood sugar control.
ANTIOXIDANTS AND OXIDATIVE STRESS IN DIABETES MELLITUS
Authors: Debasrita Banerjee Mr.
Published: June 2024

The frequency of diabetes mellitus, a common metabolic condition, has significantly increased among adults worldwide. Based on projections, there might be a significant increase to 30 million cases by 2025, which is a concerning rise from 135 million cases in 1995. This long-term illness, which is the fourth largest cause of death worldwide, mostly affects people between the ages of 45 and 65. One important etiological component of diabetes is revealed to be oxidative stress. Diabetes complications include vascular diseases that result in amputations of limbs, an increased risk of heart disease, and poor blood vessel development that causes ulcers on the feet that do not heal. Oxidative stress is a major factor in insulin resistance and diabetic comorbidities because it is associated with the generation of free radicals. Cellular damage is a result of an imbalance between the production of free radicals and antioxidant defense systems. Through a variety of processes, antioxidants become viable therapeutic agents to combat oxidative stress in diabetes. Research demonstrates the effectiveness of plant polyphenols and antioxidant vitamins like C and E in reducing problems associated with diabetes.
MEDICINAL USES OF SOME INVASIVE ALIEN PLANTS
Authors: Geeta Patil Dr.
Published: June 2024

Although the alien species has a tendency of invasion and has negative impact on existing biodiversity ,but these exotic species also has a medicinal uses too.In this chapter, focus is given on the various traditional medicinal uses of some of the selected alien species. Total 10 plants are selected for this study which are widely used to cure different health problems.
NUTRITIONAL TRANSITION AND POOR FOOD PREFERENCES AMONG YOUNGER GENERATION: A FORERUNNER TO CHRONIC DISEASES
Authors: Geetha N
Published: June 2024

Food being the primary source of energy and health, incorporating good eating practices in people is mandatory for which it is essential to assess the existing eating habits, dietary beliefs and food preferences. Hence the present investigation was aimed to analyze the lifestyle, eating preferences among younger generation and their basic knowledge about the food they consume. Online Questionnaire administered via google form to 100 participants reveals that dietary habits and diseases are intertwined. Late night snacking and recurrent outside dining can potentially make them susceptible to infectious disease due to lack of dietary micro and macro nutrients. Besides, visiting fancy restaurants are often correlated with high social status which squeezes more people into food trends. Interestingly, when we compare the gender and eating habits, females are more health conscious than males.
GROWTH PERFORMANCE OF POULTRY PRODUCTION AND EGGS EXPORT: A CASE OF INDIA
Authors: Atiang Lavenda A. , J. D Bhatt , N. M Thaker , S. M Trivedi
Published: June 2024

Poultry is one of the most important and fastest-growing sectors of the agricultural sectors in India. Additionally, poultry products were a key contributor towards the export income of agricultural products in India. It was arguable that India with its integration into the global markets could benefit substantially from international trade in eggs and other poultry products. To take advantage of these opportunities, it was important to analyse India’s prospects in the international market of poultry products economy by estimating the growth in production and export of poultry in India and measure the growth and instability in export of eggs. Analytical tools used to study these objectives were compound annual growth rates and instability indices. The study period was 1999-00 to 2018-19. The study revealed that that growth in India’s production and export of eggs was declining for both production and export, there was a higher growth in period I (1999-00 to 2008-09) as compared to period II (2009-10 to 2018-19). There was more instability for both production and export of eggs in period I as compared to period II, however, unit value of export was more instable in period II as compared to period I.
FUTURISTIC TRENDS IN MEDICAL SCIENCES- NEWER APPROACHES TO MANAGEMENT OF GROIN HERNIAS
Authors: Upadhyay Dr. Vivek , Preet Dr. Harsh
Published: June 2024

Hernia repair surgery is one of the most frequently performed surgeries now days and the approaches have evolved significantly in recent years. Among them are a shift from autogenous tissue repair to use of synthetic and biological meshes, as well as the minimally invasive laparoscopic surgical approach. Goals of surgery include optimal repair, reduction of pain, quick recovery, and low recurrence. Today, surgeons may choose from many prosthetic meshes, fixation techniques, and surgical approaches, each with its own advantages and disadvantages. These choices allow surgeons to select the treatment that is most appropriate and will achieve the best outcomes for each individual patient. Consequently, a blend of conventional and modern techniques is frequently employed. The overarching goal driving these advancements is an enhancement in patient care, evidenced by a reduction in postoperative complications and, critically, a quicker return to daily activities.
BIOENGINEERING STRATEGIES THAT BRIDGE MEDICINE AND TECHNOLOGY
Authors: Irene Kasi Ms. Cynthia , J Patil Dr. Sharangouda
Published: June 2024

Biomedical engineering is emerging as a unifying bridge between two evolving fields, medicine and engineering. It has been instrumental in combatting diseases and ailments by advancing tools like biosensors, biomaterials, computational imaging, and artificial intelligence. These technologies empower medical professionals in their research, diagnosis, and treatment efforts. This chapter highlights the pivotal role that technological advancements in medicine have played in shaping the modern healthcare system and underscores the contributions of biomedical engineers within the healthcare delivery system
INNOVATIVE THERAPIES IN ALZHEIMER’S DISEASE
Authors: Anania Lorenzo
Published: June 2024

Alzheimer's disease predominantly affects patients over the age of 65 with progressive loss of memory and their own independence. It is recognized by the World Health Organization (WHO) as a major health-care problem. There are currently no disease-modifying therapies despite advances in understanding the pathogenesis of the disease. In this chapter we will address the definition of the disease, its pathogenesis, and current and future therapeutic strategies.
AYURVEDIC PHARMACEUTICS AND ITS RECENT TRENDS WITH SPECIAL REFERENCE TO BHAISHAJYA KALPANA
Authors: V Dr. Bhoomika , K G Dr. Purushotham , M Dr. Harshitha , K Dr. Shruthan , N Nayak Dr. Gopalakrishna
Published: June 2024

Bhaishajya Kalpana (Ayurvedic pharmaceutics) deals with processing methods for drug manufacturing and principles of drug collection, synthesis and proper usage of medicines. Over the times drug manufacturing industry has grown replacing classical Ayurvedic small scale drug manufacturing, also there is a need for modification of classical dosage form to improve patient compliance, palatability, enhancement of shelf life etc., This paper outlines the short comings of classical ayurveda dosage forms and their modifications made to overcome those short comings. The primary preparations (Pancha Vidha Kashaya Kalpana) and their modifications like Tetra Pak, Syrups, Dry powder, Ghanavati, etc. To overcome its least shelf life and other disadvantages similarly other dosage forms like Gutika, Avaleha, Satva, Sandhana Kalpana, Sneha Kalpana, Bahya Kalpana etc., can be modified into various advanced dosage forms to overcome short comings of classical dosage forms. Modified and advanced dosage forms will help to popularize Ayurvedic medicines, however classical basic principles of medicine making should not be compromised but can be effectively and judiciously modified and implemented.
AN INSIGHT INTO FOWL ADENOVIRUS INFECTION IN POULTRY
Authors: Abrol Riya , Rahman Dr. Shafiqur
Published: June 2024

Fowl adenoviruses (FAdV) are significant infectious agents infecting wide range of poultry host including parrots, falcons and ostrich having a significant negative economic impact on the global poultry industry. Because FAdV strains are so widely dispersed, the majority of avian species are susceptible to infection. Five species and 12 serotypes (A–E; 1–8a and 8b–11) make up the FAdV classification. As FAdV strains are so widely dispersed, the majority of avian species are susceptible to infection. Chicken production can be affected by a number of syndromes brought on by fowl adenoviruses (FAdVs), including Inclusion Body Hepatitis (IBH), Hepatitis-Hydropericardium Syndrome (HHS) and others which can result in significant financial losses across the world. Because fowl adenoviruses (FAdVs) are more common than occasional outbreaks and there are differences across experimental studies, the stand-alone pathogenicity of FAdVs has been a topic of discussion for a while. However, during the past 20 years, a global pattern of FAdV-associated disorders has emerged, with epidemics of inclusion body hepatitis that are more widely dispersed geographically and hepatitis-hydropericardium syndrome occurring more in Asia. When Adenoviral Gizzard Erosion (AGE) first appeared in Asian and European countries, the spectrum of disorders was fully completed. Poultry industry's shift to highly specialised genetic breeds and strict biosecurity measures also contributes to the rising prevalence of diseases linked to FAdV. Additionally, increased biosecurity regulations have resulted in breeding stocks with weak immune systems, putting broilers at danger from vertical FAdV transmission. Therefore, in the future, breeders should have appropriate antibodies before production, and vaccination should be employed as a part of prophylactic efforts to safeguard progeny.
ADVANCEMENTS IN MAXILLOFACIAL PROSTHETIC MATERIALS
Authors: Sinha Dr. Divyansh , Maiti Dr. Subhabrata
Published: June 2024

Maxillofacial prosthetics is a subspecialty of Prosthodontics that involves rehabilitating patients with defects or disabilities that are congenital or acquired due to trauma, violence, and gunshot injuries in the head and neck region. Such prostheses replace soft and/or hard tissues and restore aesthetics as well as oral functions. The prostheses can be made from a variety of materials. This chapter elucidates the past, present and future in the scope of materials in maxillofacial prosthetics. From acrylic resins, silicones and its modifications to bioprinting and functional maxillofacial prosthetics, this chapter discusses the current state of the art in this field.
SCOPE OF PHARMACOVIGILANCE IN HOMOEOPATHY
Authors: Chandran K Dr. Swetha
Published: June 2024

Pharmacovigilance plays a crucial role in monitoring and ensuring the safety of pharmaceutical products. While traditionally associated with conventional medicine, the scope of pharmacovigilance has expanded to encompass various alternative systems of medicine, including homoeopathy. Homoeopathy is a holistic medical system that utilizes highly diluted substances to stimulate the body's natural healing processes. With the growing popularity and use of homoeopathic remedies worldwide, it is essential to establish a robust pharmacovigilance framework to monitor and assess their safety and efficacy. This article explores the scope of pharmacovigilance in homoeopathy, highlighting its significance, challenges, and potential benefits for patients, healthcare professionals, and regulatory authorities.
ARTIFICIAL INTELLIGENCE IN MEDICAL EDUCATION
Authors: Nair Dr. Arun R
Published: June 2024

This book chapter explores the transformative effect of synthetic intelligence (AI) on medical education, a area at the intersection of cutting-edge era and healthcare pedagogy. As advancements in AI preserve to reshape diverse industries, the world of clinical education is witnessing a paradigm shift, leveraging AI gear to beautify learning outcomes, enhance medical abilities, and put together the subsequent generation of healthcare specialists. The bankruptcy gives an in-depth examination of the contemporary state of AI integration in clinical training, encompassing shrewd tutoring systems, digital affected person simulations, adaptive getting to know systems, and facts-pushed insights. Furthermore, it delves into the demanding situations and possibilities presented through AI, addressing issues related to ethics, records privacy, and the evolving function of educators on this technologically enriched landscape. Through a complete evaluation of existing literature, case research, and emerging trends, this bankruptcy aims to offer treasured insights for educators, healthcare experts, and policymakers navigating the dynamic panorama of AI in medical training. The synthesis of theoretical frameworks and realistic packages on this chapter contributes to a nuanced knowledge of the role AI plays in shaping the future of clinical training, in the long run fostering more talented and adaptive healthcare professionals.
ADVANCEMENTS IN NON-INVASIVE ORAL CANCER DETECTION: UNVEILING INSIGHTS FROM CIRCULATING MIRNA PROFILING
Authors: Poongodi Dr. R. , Arundhathi Dr. S. , Sudhakar Dr. R.
Published: June 2024

Within the pages of this book chapter lies an in-depth exploration of the present status of circulating miRNAs, illuminating their promising role in the realm of oral cancer detection. These microRNAs (miRNAs), small yet powerful non-coding RNA molecules, are pivotal in orchestrating gene expression regulation. Recent research breakthroughs have unwrapped their potential as biomarkers across various diseases, with oral cancer being no exception. This chapter delves into the profound significance of miRNAs, unraveling the methodologies employed in their detection, and shedding light on their distinct expression profiles as they relate to oral cancer. Moreover, this chapter embarks on an insightful journey through the potential diagnostic and prognostic value held by miRNAs in the context of oral cancer. Beyond the promising aspects, the challenges entwined with integrating circulating miRNAs into clinical practice find their place in these discussions. Looking forward, the book chapter aims to guide the reader through the potential pathways that the utilization of circulating miRNAs might follow, thus shaping the future landscape of oral cancer detection and patient care.
DESIGNING AND DOCKING STUDIES OF ARYL BIOISOSTERES OF ENZALUTAMIDE FOR PROSTATE CANCER THERAPY
Authors: Kumar Gupta Ajay , Kumar Jain Sanmati
Published: June 2024

Cancer is a major health problem throughout the world. Androgens like testosterone and dihydrotestosterone are essential for the growth and development of the prostate gland. Androgenic receptors are overexpressed, which promotes the progression of prostate cancer (PC) therefore, androgenic receptors are a key target in the therapy of PC. A non-steroidal antiandrogen drug called enzalutamide (ENZ) is used to treat PC; however, it also causes toxicities such as cardiovascular toxicity, acute myocarditis, hypertension, and seizures. The study's goal is to use a bioisosteric approach to replace the aryl group in the ENZ molecule in order to generate a less toxic analogues with improve pharmacokinetic properties and reduce toxicity. The physicochemical, medicinal, pharmacokinetic, and toxicological characteristics of the designed analogues were calculated using ADMETlab 2.0. Drug likeness (DL) and drug score (DS) of analogues were calculated using OSIRIS property explorer (PEO). The docking analysis of designed ENZ analogues was carried out with the help of AutoDock Vina (ADV). Designed analogues met the requirements for acceptability and followed the Lipinski rule of five. The ADMET profile of designed analogues was found to be optimal to good. However, no hydrogen bond was found in docking interactions between ligands and protein. Based on their QED score, ADMET properties, toxicity score, DL, DS and docking interactions, ligands E6 and E20 may be used for further screening as androgen receptor (AR) antagonists in management of PC.
SOLUTION OF SINGULAR PERTURBATION PROBLEMS USING FOURTH ORDER ADAPTIVE CUBIC SPLINE
Authors: Kodipaka Mamatha
Published: June 2024

In this paper, using adaptive cubic spline, we have suggested a numerical scheme for solving a convection-diffusion problem having layer structure. The numerical scheme is derived with this spline and non-standard finite differences of the first derivative. The tridiagonal solver is used to solve the system of the numerical method. The analysis of convergence of the method is briefly discussed and the fourth order is shown. The numerical results of the examples were tabulated and compared to the existing computational results in order to support the higher accuracy of the proposed numerical scheme.
HARNESSING THE POWER OF SURFACE-MODIFIED NANOPARTICLES FOR SUSTAINABLE WASTEWATER REMEDIATION
Authors: Karki Archana , Kumar Verma Deepak , Sarkar Anjana , Kashyap Shivam
Published: June 2024

Wastewaters refer to the combination of solid and liquid substances that are released into water bodies, encompassing the byproducts generated from both community activities and industrial processes. The treatment of wastewater has become a significant concern in relation to its impact on the environment and the organisms that inhabit it. Typically, the process of wastewater treatment involves the integration of several physical, chemical, and biological procedures and activities aimed at eliminating insoluble particulates and soluble pollutants from effluent streams. In order to enhance the efficacy of the materials and procedures employed in various waste water treatment systems, it is advisable to consider certain measures. These measures may include the utilization of non-toxic chemicals for the eradication of hazardous microorganisms, as well as the optimization of disinfectant concentrations, among others. This chapter focuses on the utilization of surface modified nanoparticles for the purpose of wastewater cleanup. Surface-modified nanoparticles refer to nanoparticles or nanoscale materials that have undergone modifications to their surface properties. These alterations serve various purposes, including enhancing stability, functionalizing the nanoparticles, improving biocompatibility, or augmenting barrier capabilities. Different types of nanoparticles can be employed in the treatment of wastewater, including iron oxide nanoparticles, carbon nanotubes, titanium dioxide nanoparticles, zinc oxide nanoparticles, aluminium oxide nanoparticles, and polymeric nanoparticles. The selection of these nanoparticles is based on their unique characteristics and significant surface area. In this context, the focus is on the investigation of the role of TiO2 nanoparticles due to its positive properties such as photocatalytic activity, high surface area, and chemical stability, among others, which have been extensively covered in the preceding chapter. The objective is to assess their effectiveness in alleviating the issue of wastewater pollution. This chapter provides a concise overview of the overall framework of wastewater treatment, while also examining the merits and drawbacks of various methods applicable to diverse contexts.
A STUDY ON TECHNO-ECONOMICFEASIBILITY OF LOW SALINITY WATER FLOODING FOR ENHANCING CRUDE OIL RECOVERY
Authors: Borah Rishikesh , Dutta Ananya , Deori Leema , Neog Dhrubajyoti
Published: June 2024

This study presents a techno economic analysis of low-salinity water flooding for enhancing crude oil recovery from brown oil fields. The objective of the current work is to assess the feasibility, economic viability, and potential benefits of implementing low-salinity water flooding techniques in petroleum reservoirs. The present work presents an overview of importance of water flooding in enhancing crude oil recovery. It introduces low-salinity water flooding as an emerging technique for improving oil recovery. The current work reviews previous research to highlight the mechanisms behind improved oil recovery and also refers to some of the laboratory results from experiments and field-scale applications. The analysis evaluates the impact of low-salinity water flooding on oil recovery, considers associated reservoir parameters, and identifies potential implementation challenges. The results indicate the potential advantages of low-salinity water flooding, including increased oil recovery and cost-effectiveness. The study concludes that low-salinity water flooding holds promise as an effective EOR technique and recommends further research and field applications to explore its full potential. This techno-economic analysis contributes to understanding low-salinity water flooding and provides valuable insights for decision-makers in the petroleum industry.
IMPORTANCE OF MENTAL HEALTH AT THE WORKPLACE
Authors: Sharma Dr. Meenu
Published: June 2024

Over the last two decades, there has been an increasing issue of mental health in all spheres of individual life. In the contemporary scenario, workplace stress found one of the significant factors of poor mental health. As per World Health Organization report more than half the world’s population are currently in work and 15% of working-age adults live with a mental disorder. Without effective support, mental disorders and other mental health conditions can affect a person’s confidence and identity at work, capacity to work productively, absences and the ease with which to retain or gain work. At the same time, work can be a protective factor if it is constructive and balanced with life, suggested by recent studies. Also work-related mental health issues are preventable. This paper highlights the importance of mental health in the workplace and its multifaceted impact. Moreover, it also discusses ways of handling work stress and various means and strategies to overcome stress to improve mental health and well-being. Last part of this paper also suggests fostering a mentally healthy workplace culture by addressing its associated stigma, legal policies and employee support programs etc. Indeed, a culture of understanding and empathy is a fundamental aspect of promoting mental health and it can be attained by implementing support mechanisms at the workplace.
SUSRUTA SAYS ON DIET, REGIMEN AND HEALTH
Authors: Goswami Prof. (Dr.) Dilip Kr.
Published: June 2024

Health is the status of absolute equilibrium of the body, mind and soul . All the structural and functional components of the body, the mental faculties, when remain in balance qualitatively and quantitatively and the spiritual peace is also maintained then the individual can work smoothly . Diet and regimen have an important role in maintaining the physical and mental health. Every living needs diet to maintain the body integrity. The natural demand of diet is expressed by hunger. For the other living organisms nature has fixed a class of diet and they take accordingly by searching and collecting from the surroundings. But the human beings, due to intelligence, take a wide range of diet some are collected from the nature directly and some are also prepared artificially according to their choice and availability. In most of the situations diet is prepared by combining more than one ingredient by mixing some additives to make it tasty and assimilable by the body .But , during the process of making the combinations and preparations sometimes some faults are made and it may cause some suffering to the user . Hence the Ayurvedic authors give importance on the process of selection, preparation and use etc. of the food. An effort to discuss on the concepts of Susruta , the father of Indian Surgery, on the topic is considered eye opening .
NEED OF THE HOUR-MANDATING COVID-19 VACCINATION: ETHICAL OR NON-ETHICAL?
Authors: Naik Dr. Shweta Sagar , Maheswary Dr. D. , Gopinathan Dr. Anusha , Leela Dr. K. V
Published: June 2024

The world has been battling with COVID-19 pandemic for almost two years now. Despite intensive research in treatment, none of the currently licensed therapeutic options are completely effective in all patients. This leaves vaccines as the one of the most effective tools for protection against COVID-19. Since the deadliest modern-day pandemic the world has seen has multifactorial impact on the healthcare, economy and welfare of society, Government authorities have been pushed to consider mandatory vaccination. Contemporary forms of “mandatory vaccination” compel vaccination by direct or indirect threats of imposing restrictions in cases of non-compliance.It is a matter of public debate whether such policies can be ethically justified. On one hand they may be crucial to protect the health and well-being of the public while on the other,the policies that mandate vaccination restrict individual liberty and autonomy. The nature of the COVID-19 pandemic and evidence on vaccine safety and effectiveness continue to evolve. Given the lacunae of data on the long term safety and efficacy of COVID-19 vaccines, the future consequences of vaccination and who will take the onus for them remains questionable. Indirect “mandatory vaccination” policies limit individual choice by constraining the options for education, work and travel. The absence of a free and sufficient supply to vaccination creates an unfair demand on those who are required to be vaccinated but are unable to access the vaccine. This chapter discusses significant ethical considerations and stipulations that should be explicitly evaluated while implementing mandatory COVID vaccination without taking a stand that endorses or opposes mandatory COVID-19 vaccination.
ADVANCEMENT IN DENTISTRY
Authors: Paul Dr. Abonish
Published: June 2024

This article explores the profound impact of digital technology on patient care, with a focus on dentistry and its global significance outlined by the WHO's Global Strategy on Digital Health. Highlighting technological advancements, including virtual reality, artificial intelligence, and CRISPR, the article discusses their contribution to alternative treatments and enhanced oral healthcare. Wearable biosensors, intelligent toothbrushes, and augmented reality are dissected as integral components of this transformative journey. The future of dentistry is envisioned through the lens of artificial intelligence, exploring personalized diagnostics, intelligent toothbrush monitoring, and immersive virtual reality experiences for students and patients. The concept of "phone dentistry" and tele-dentistry is introduced, providing convenient access to oral care, especially for remote populations. The integration of microchips, known as "intelligent teeth," is discussed for continuous monitoring, alongside the impact of computer-assisted design and 3D printing on dental solutions. The article envisions a future where digital health technologies revolutionize patient care and education globally, transcending geographical barriers.
ROLE OF CANCER STEM CELLS IN RADIORESISTANCE OF HEAD AND NECK SQUAMOUS CELL CARCINOMA
Authors: Devi Dr. Priya , John Dr. Sharon , Jain Dr. Ayushi , Gupta Dr. Shalini
Published: June 2024

Cancer stem cells (CSCs) are incredibly uncommon immortal cells that can be self-renewed by dividing and give rise to a wide variety of tumor-initiating cell types. Additionally, it is demonstrated that CSCs play a crucial role in metastatic spread and cell proliferation. Indisputable data reveals that cancer stem cells (CSCs) may be responsible for tumour recurrence if they are not eliminated by radiotherapy or radio-chemotherapy, two common modern treatments. Locally advanced head and neck squamous cell carcinoma (HNSCC), Despite recently made improvements in therapeutic methods and understanding of the molecular pathophysiology, continues to have a poor prognosis. Typically, CSCs are resistant to chemotherapy and radiation treatment, remaining CSCs that are still present after treatment may be able to survive and encourage cancer recurrence and resistance to treatments. In this review we address the role of CSCs and its mechanism in the resistance to therapy.
FORENSIC ODONTOLOGY: THE NEW DIMENSION IN DENTAL ANALYSIS
Authors: Gupta Dr Shikha , Yadav Dr Indu , Nidhi Dr , Gupta Dr Shailesh
Published: June 2024

Forensic odontology a branch of Forensic sciences uses the skill of the dentist in identification during mass calamities ,sexual assault and child abuse1 .Identification of human remains is essential for various section as including legal, criminal, humanitarian and social grounds.1 Dental remains used for identification as it is cost effective, reliable and fast. Forensic odontology is a branch of dentistry that analyses dental evidence to overlap the dental and legal profession. Forensic information from soft tissues of the oral cavity, forensic methods of age estimation, therapeutic and molecular aspects of Forensic odontology have been elaborated.
COMPARISON OF INKJET PRINTED, LASER PRINTED AND PHOTOCOPIED DOCUMENTS
Authors: P Gomathi.
Published: June 2024

In recent years, forensic document technology which primarily focuses on tracing a document's origin or identifying forgeries has advanced quickly. Commodity scanners and a computer are used in this technology to carry out the required evaluations. Printer, forgery, and scanner identification have been the main topics of recent document forensics research.The requirement for printer inspection in questioned document examination has arisen in the modern period as a result of the growing use of printers in document generation as opposed to handwritten documents and the counterfeiting of documents produced by different printers.Inkjet printers, laser printers, and photocopiers—three frequently used document creation devices were studied under a microscope to determine how they differ from one another. Based on characteristics seen in the characters in the papers, the suggested approach can distinguish between documents created by various sources. Thus, it can also be used to identify documents that have been altered and come from a combination of various sources.
ASPROSIN IN METABOLIC SYNDROME
Authors: Ashem Florida , Hijam Davina
Published: June 2024

Metabolic Syndrome (MetS) is a group of clinical features that include insulin resistance, obesity, impaired fasting glucose and elevated blood pressure. Asprosin is an adipokine having 140 amino acid C-terminal profibrillin (encoded by FBN1) which was discovered recently. It is mainly synthesised and released by white adipose tissue during fasting state. Regulation of both glucose and lipid metabolism, and insulin resistance is associated with asprosin. It is considered to play a complex role in metabolic diseases. In recent studies, it is found that serum asprosin levels are increased in T2DM, obesity and polycystic ovary syndrome, which are associated with elevated fasting glucose and triglyceride. As MetS is strongly associated with lipid homeostasis, glucose and insulin resistance, serum asprosin levels are found to be altered in MetS.
BASIC CONCEPTS OF SJOGREN'S SYNDROME (SS)
Authors: K Dr. Nivedha. , G Dr. Savitha.
Published: June 2024

Sjogren's syndrome (SS) is an autoimmune disease characterized by Sicca syndrome, dry skin, vaginal dryness, and also associated with other autoimmune disorders like Rheumatoid arthritis, Systemic lupus erythematous due to lymphoproliferation. It is classified into Primary & Secondary Sjögren's syndrome (SS)& the current European-American Criteria have been given and validated for the Primary Sjögren's syndrome (SS). It is multifactorial disorder& affects the age group of 40-50 years. Investigation is based upon imaging technology, schimmer’stest, Rose Bengal test& the treatment is given by the interdisciplinary team & immunosuppressive drugs.
DYNAMIC PLAIN CIPHER ALGORITHM
Authors: Raja J. Karthik
Published: June 2024

This paper aims to review Dynamic Plain Cipher Algorithm .Developed to overcome the disadvantage of RSA, examine its different versions to overcome the weakness of RSA (Rivest Shamir Adleman ).RSA is one of the best cryptographic algorithms in use today that ensures secure communication over networks .The Dynamic Plain Cipher Algorithm is developed by Karthik Raja J (3BCA) from SRMArts & ScienceCollege Department of Computer Applications and Technology in 2023 .
BLOCKCHAIN AND AI FOR AGRICULTURE
Authors: Mishra Anand Kumar , Raghuvanshi C. S.
Published: June 2024

This abstract delves into the potential of merging Blockchain and AI in agriculture, exploring how these technologies can shape the future of the industry. Blockchain offers transparency and trust in the supply chain, empowering consumers and automating transactions through smart contracts. AI enhances farming with data analytics and robotics, optimizing yields and resource usage. The synergy of Blockchain and AI ensures secure and automated processes, reducing fraud and offering insights from agricultural data. Predictive analytics from AI enable adaptive farming, efficient supply chains, and fair compensation. Decentralized marketplaces on Blockchain connect farmers directly with consumers, promoting equity. Furthermore, these technologies support sustainability by monitoring and verifying eco-friendly practices. In conclusion, this convergence holds the potential to revolutionize agriculture, fostering transparency, efficiency, and sustainability in a technologically transformed food ecosystem.
BLOCKCHAIN TUNING IN THE BANKING SECTOR: IMPROVING SECURITY, EFFICIENCY, AND TRUST
Authors: Kulhari Vivek , Banerjee Minali
Published: June 2024

This research paper comprehensively expands on the importance of the applications of blockchain technology in the banking industry and its implications for security enhancement, efficiency, and building trust. By leveraging its decentralized and immutable nature, block chain technology can address longstanding challenges in traditional banking systems, offering enhanced security, transparent border transactions, streamlined internal processes, and improved customer experiences. In addition to the advancement and transformation of financial and banking systems, this article is particularly interested in the eco-sociological and organizational changes brought about by the adoption of block chain-based information systems as an alternative to current legacy systems, particularly in the financial services sector. However, the literature in this field is still in its infancy, and we do not yet have a comprehensive understanding of the possible consequences of block chain technology due to regulatory concerns for banks. International banks have already started on project-based enhancement in their systems using the blockchain infrastructure. Regulators are in transit of creating proposals to financial institutions based on the historical performance of the technology. The paper reviews prior research on the topic, outlines the research methodology, presents the objectives, analyses the key findings, and concludes with insights on the future of blockchain in the banking sector. Additionally, it gives a general overview of the possible benefits and challenges of blockchain technology in the banking/ financial industry.
RESIDUAL MULTI-LAYERED PERCEPTRON DESIGN AND ANALYSIS
Authors: Kiruthiga C. , K. Dharmarajan Dr.
Published: June 2024

The latest advances in technology have made it possible for the food sector to create more food in less time, which has a multiplicative impact on the ability of the business to make a profit. In this study, all pertinent context is included in a thorough literature analysis of prior studies on the use of machine learning and AI in the food business. To adequately depict the distinctive qualities connected to each eating place, we use nested feature groups. For every order that has the current dish listed among the dish- and restaurant-related variables, we compute the forecast. The outcomes demonstrate the efficacy of our method and the potential for further improvement by adjusting the MLP model utilising residual model precision.
DEEP LEARNING APPROACHES FOR IDENTIFYING CYBER ATTACKS IN DATA SCIENCE
Authors: Ratna Dr. S. Raja , Gangadevi Dr. G. , Jeya Dr. J. Jospin
Published: June 2024

Cyber-attacks are a growing hazard to cyber- physical systems, and firms that handle sensitive data must be able to identify and anticipate these attacks. Because the types of Cyber Attacks are becoming more diverse, anti-virus scanners alone are no longer adequate to offer protection. The growth of Internet of Things (IoT) devices has led to significant increases in cyber security vulnerabilities, and the market for software is growing as more software is used in more aspects of daily life. Hackers launch cyber-attacks in a variety of ways, including Phishing, Dos, R2L, Probing, Malware, and U2R. Large data sets can occasionally be compromised without the affected parties' knowledge, which can cause serious interruptions to business continuity and large financial losses. By examining security data, Machine Learning technology is essential for providing an automated, dynamically improved, and up to security system. Large datasets may be handled by Machine Learning technology, which also provides greater visualization capabilities. Due to built-in weaknesses and threats that can be used at any stage in the system, supply chain security is difficult. Our study's findings demonstrate that the majority of rules exhibit steady support and confidence values, enabling the prediction of Cyber Attacks over a period of days without the need for daily rule updates.
A SURVEY ON TEXT CLASSIFICATION USING DIFFERENT MACHINE LEARNING APPROACHES
Authors: Sekharreddy B. Veera , Thatha Venkata Nagaraju , Kiran G. Uday , Srilakshmi V. , Sanapala Srinuvasarao
Published: June 2024

Since machine learning-based text categorization has so many practical applications, such as spam detection, hate speech identification, review summarization, rating analysis, sentiment modelling, and topic modelling, it is one of the most actively researched fields. Many different datasets, training methods, performance metrics, and comparison methods are used in popular machine learning studies. This paper's systematic review followed the guidelines laid out in the Preferred Reporting Items for Systematic Reviews (PRISMA) statement. Datasets, ML models, best accuracy, performance evaluation metrics, MT model comparisons, MT model splitting techniques, and MT model comparisons are all explored and analysed in the literature. We also point out omissions and make recommendations for further research in the field. While the reviewed works do a good job at classifying texts, there is room for improvement. We want for this literature review to serve as a resource for scholars and professionals in the field of text categorization.