bluuebunny/crossref_metadata_2025 huggingface dataset:
Near telomere-to-telomere genome assemblies of Silkie Gallus gallus and Mallard Anas platyrhynchos restored the structure of chromosomes and “missing” genes in birds
Authors: Zhao Qiangsen , Yin Zhongtao , Hou Zhuocheng
Published: January 2025

Background

Chickens and ducks are vital sources of animal protein for humans. Recent pangenome studies suggest that a single genome is insufficient to represent the genetic information of a species, highlighting the need for more comprehensive genomes. The bird genome has more than tens of microchromosomes, but comparative genomics, annotations, and the discovery of variations are hindered by inadequate telomere-to-telomere level assemblies. We aim to complete the chicken and duck genomes, recover missing genes, and reveal common and unique chromosomal features between birds.

Results

The near telomere-to-telomere genomes of Silkie Gallus gallus and Mallard Anas platyrhynchos were successfully assembled via multiple high-coverage complementary technologies, with quality values of 36.65 and 44.17 for Silkie and Mallard, respectively; and BUSCO scores of 96.55% and 96.97% for Silkie and Mallard, respectively; the mapping rates reached over 99.52% for both assembled genomes, these evaluation results ensured high completeness and accuracy. We successfully annotated 20,253 and 19,621 protein-coding genes for Silkie and Mallard, respectively, and assembled gap-free sex chromosomes in Mallard for the first time. Comparative analysis revealed that microchromosomes differ from macrochromosomes in terms of GC content, repetitive sequence abundance, gene density, and levels of 5mC methylation. Different types of arrangements of centromeric repeat sequence centromeres exist in both Silkie and the Mallard genomes, with Mallard centromeres being invaded by CR1. The highly heterochromatic W chromosome, which serves as a refuge for ERVs, contains disproportionately long ERVs. Both Silkie and the Mallard genomes presented relatively high 5mC methylation levels on sex chromosomes and microchromosomes, and the telomeres and centromeres presented significantly higher 5mC methylation levels than the whole genome. Finally, we recovered 325 missing genes via our new genomes and annotated TNFA in Mallard for the first time, revealing conserved protein structures and tissue-specific expression.

Conclusions

The near telomere-to-telomere assemblies in Mallard and Silkie, with the first gap-free sex chromosomes in ducks, significantly enhanced our understanding of genetic structures in birds, specifically highlighting the distinctive chromosome features between the chicken and duck genomes. This foundational work also provides a series of newly identified missing genes for further investigation.
Evaluation of EGFR-TKIs and ICIs treatment stratification in non-small cell lung cancer using an encrypted multidimensional radiomics approach
Authors: Zhang Xingping , Qiu Xingting , Zhang Yue , Lai Qingwen , Zhang Yanchun , Zhang Guijuan
Published: January 2025

Background

Radiomics holds great potential for the noninvasive evaluation of EGFR-TKIs and ICIs responses, but data privacy and model robustness challenges limit its current efficacy and safety. This study aims to develop and validate an encrypted multidimensional radiomics approach to enhance the stratification and analysis of therapeutic responses.

Materials and methods

This multicenter study incorporated various data types from 506 NSCLC patients, which underwent preprocessing through anonymization methods and were securely encrypted using the AES-CBC algorithm. We developed one clinical model and three radiomics models based on clinical factors and radiomics scores (RadScore) of three distinct regions to evaluate treatment response. Additionally, an integrated radiomics-clinical model was created by combining clinical factors with RadScore. The study also explored the association between different EGFR mutations and PD-1/PD-L1 expression in radiomics biomarkers.

Findings

The radiomics-clinical model demonstrated high performance, with AUC values as follows: EGFR (0.884), 19Del (0.894), L858R (0.881), T790M (0.900), and PD-1/PD-L1 expression (0.893) in the test set. This model outperformed both clinical and single radiomics models. Decision curve analysis further supported its superior clinical utility. Additionally, our findings suggest that the efficacy of EGFR-TKIs and ICIs therapy may not depend on detecting a singular tumor feature or cell type.

Conclusion

The proposed method effectively balances the level of evidence with privacy protection, enhancing the study’s validity and security. Therefore, radiomics biomarkers are expected to complement molecular biology analyses and guide therapeutic strategies for EGFR-TKIs, ICIs, and their combinations.
Dual-modal radiomics ultrasound model to diagnose cervical lymph node metastases of differentiated thyroid carcinoma: a two-center study
Authors: Tang Jiajia , Tian Yan , Ma Jiaojiao , Xi Xuehua , Wang Liangkai , Sun Zhe , Liu Xinyi , Yu Xuejiao , Zhang Bo
Published: January 2025

Objectives

To establish and validate a dual-modal radiomics nomogram from grayscale ultrasound and color doppler flow imaging (CDFI) of cervical lymph nodes (LNs), aiming to improve the diagnostic accuracy of metastatic LNs in differentiated thyroid carcinoma (DTC).

Methods

DTC patients with suspected cervical LNs in two medical centers were retrospectively enrolled. Pathological results were set as gold standard. We extracted radiomic characteristics from grayscale ultrasound and CDFI images, then applied lasso (least absolute shrinkage and selection operator) regression analysis to analyze radiomics features and calculate the rad-score. A nomogram based on rad-score, clinical data, and ultrasound signs was developed. The performance of the model was evaluated using AUC and calibration curve. We also assessed the model’s diagnostic ability in European Thyroid Association (ETA) indeterminate LNs.

Results

377 DTC patients and 726 LNs were enrolled. 37 radiomics features were determined and calculated as rad-score. The dual-modal radiomics model showed good calibration capabilities. The radiomics model displayed higher diagnostic ability than the traditional ultrasound model in the training set [0.871 (95% CI: 0.839–0.904) vs. 0.848 (95% CI: 0.812–0.884), p<0.01], internal test set [0.804 (95% CI: 0.741–0.867) vs. 0.803 (95% CI: 0.74–0.866), p = 0.696], and external validation cohort [0.939 (95% CI: 0.893–0.984) vs. 0.921 (95% CI: 0.857–0.985), p = 0.026]. The radiomics model could also significantly improve the detection rate of metastatic LNs in the ETA indeterminate LN category.

Conclusions

The dual-modal radiomics nomogram can improve the diagnostic accuracy of metastatic LNs of DTC, especially for LNs in ETA indeterminate classification.
Effect of doping Mn ion on the crystal structure and cation distribution in Co1-xMnxFe2O4 compounds
Authors: Tran T. A. , Tran H. C. , Nghiem N. T. , Truong-Son L. V. , Imanova G. T. , Jabarov S. H.
Published: January 2025

In this study, we investigated the effect of Mn doping on the crystal structure and the distribution of cations at tetrahedral and octahedral sites in Co1-x
Mn
x
Fe2O4 compounds (0 ≤ x ≤ 0.4), synthesized utilizing a solid phase reaction method, utilizing X-ray diffraction (XRD) and Raman spectroscopy measurements. The surface morphology and chemical composition of the compounds were studied using scanning electron microscope and X-ray energy dispersive spectroscopy. The Rietveld refinement of XRD data using the Fullprof package demonstrate that all studied samples are single phase spinels with no other detectable phases and have a cubic structure with the space group of Fd-3 m. The lattice constant and unit-cell volume increased with increased Mn doping concentration, which are attributed to the larger ionic radius of Mn in comparison with Co. Both the X-ray diffraction and Raman spectroscopy results demonstrated that doping Mn at the Co-site leads to the movement of Fe cations from the tetrahedral sites to the octahedral ones.
Developing a data pricing framework for data exchange
Authors: Majumdar Rupsa , Gurtoo Anjula , Maileckal Minnu
Published: January 2025

Despite emergence of data markets such as Windows Azure Marketplace and India Urban Data Exchange (IUDX), comprehensive frameworks to determine data pricing and/or determine parameters for profit maximization remain a gap. Data valuation often gets guided by the sellers, ignoring the interests of the buyers. The information asymmetry results in lopsided pricing. The data sellers fail to price optimally, and the buyers are unable to optimize their purchasing decisions, thus, reinforcing the need for a structured data pricing framework. The paper reviews literature and applies the stages as reported by Ritchie and Spencer (in: Bryman, Burgess (eds) Analysing qualitative data, Routledge, London, 1994) for applied policy research to determine the main approaches of data pricing and develop a comprehensive pricing framework. Literature selection on pricing attributes and content analysis classifies data pricing models into five broad but distinct themes, based on the data pricing method, namely data characteristics-based pricing, quality-based pricing, query-based pricing, privacy-based pricing, and organizational value-based pricing. Application of the Ritchie and Spencer stages identifies eight factors, namely customer need, customer assigned value, market maturity, market structure, usable data, data quality, seller reputation and seller objectives as defining and intersecting with the five pricing models. A framework is hence developed to guide data pricing. Thereby, the paper creates a platform for prescribing data pricing formulas.
Posterior reversible encephalopathy syndrome in a young male with IgA nephropathy and chronic kidney disease: a case report from the Maldives
Authors: Dey Rajib Kumar , Khadka Gunjan , Ishaq Shifa , Jaleel Aishath Zeena Abdul , Moosa Aminath Shafeenaz , Muslim Saifullah , Nazeem Ali
Published: January 2025

Background

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological condition which is commonly associated with chronic kidney disease (CKD), hypertensive encephalopathy, eclampsia, and the use of cytotoxic drugs. It can cause vasogenic edema of the brain and is characterized by nausea, vomiting, headache, seizures, visual changes, and other focal neurological deficits. Acute hypertension is a predisposing factor for PRES which can occur in CKD patients due to fluid overload. Uremia in CKD patients is also one of the factors for developing PRES. Neuroimaging findings involve posterior white matter edema commonly affecting the parietal and occipital lobes. However, involvement of a non-posterior distribution, mainly in watershed areas, including within the frontal, inferior temporal, cerebellar, and brainstem regions, has been reported.

Case presentation

This case report discusses a case of a 27-year-old male with underlying IgA nephropathy, who presented with generalized throbbing headache, along with 1-day history of nausea and vomiting. This was followed by blurring of vision and 2 episodes of abnormal jerky movements of the body on the first day of admission. On examination, he was found to be hypertensive with no focal neurological deficits. Magnetic resonance imaging (MRI) T2/fluid-attenuated inversion recovery (FLAIR) findings showed hyperintense areas on the right frontal periventricular and right parietal and bilateral occipitotemporal lobes which was suggestive of PRES. The patient was treated with antiepileptics and antihypertensives and was started on dialysis following which his condition improved, and he was discharged in stable condition.

Conclusion

Symptoms of PRES are usually reversible unless cerebral hemorrhage or ischemia has occurred which can result in irreversible neurological deficit or death. Hence, it is crucial to identify and manage PRES promptly. Clinical suspicion and radiological findings aid in early diagnosis. It is also important to be aware of uncommon radiological findings (involvement of the right frontal periventricular area) as in our case.
Allelic variation in an expansin, MdEXP-A1, contributes to flesh firmness at harvest in apples
Authors: Su Qiufang , Feng Yifeng , Li Xianglu , Wang Zidun , Zhong Yuanwen , Zhao Zhengyang , Yang Huijuan
Published: January 2025

Flesh firmness is a core quality trait in apple breeding because of its correlation with ripening and storage. Quantitative trait loci (QTLs) were analyzed through bulked segregant analysis sequence (BSA-seq) and comparative transcriptome analysis (RNA-seq) to explore the genetic basis of firmness formation. In this study, phenotypic data were collected at harvest from 251 F1 hybrids derived from ‘Ruiyang’ and ‘Scilate’, the phenotype values of flesh firmness at harvest were extensively segregated for two consecutive years. A total of 11 candidate intervals were identified on chromosomes 03, 05, 06, 07, 13, and 16 via BSA-seq analysis. We characterized a major QTL on chromosome 16 and selected a candidate gene encoding expansin MdEXP-A1 by combining RNA-seq analysis. Furthermore, the genotype of Del-1166 (homozygous deletion) in the MdEXP-A1 promoter was closely associated with the super-hard phenotype of F1 hybrids, which could be used as a functional marker for marker-assisted selection (MAS) in apple. Functional identification revealed that MdEXP-A1 positively expedited fruit softening in both apple fruits and tomatoes that overexpressed MdEXP-A1. Moreover, the promoter sequence of TE-1166 was experimentally validated containing two binding motifs of MdNAC1, and the absence of the MdEXP-A1 promoter fragment reduced its transcription activity. MdNAC1 also promotes the expression of MdEXP-A1, indicating its potential modulatory role in quality breeding. These findings provide novel insight into the genetic control of flesh firmness by MdEXP-A1.
The Bell Jar: allow the humanities to humanise
Authors: Pushkar Piyush
Published: January 2025

This commentary responds to Carona & Atanázio's discussion of Sylvia Plath's novel The Bell Jar in this issue of BJPsych Advances. Although I agree with their emphasis on empathy and sensitivity in medical practice, I argue that they overlook the broader insights of the medical humanities. By examining themes of suicide and patriarchy in The Bell Jar, I highlight how the novel itself, and the humanities scholars who have studied it, provide a counternarrative to the biomedical model, urging a more holistic understanding of psychological distress. I advocate engaging with Plath's work beyond diagnostic criteria, appreciating its cultural and structural dimensions.
Financial literacy among young college students: Advancements and future directions
Authors: Rodríguez-Correa Paula Andrea , Arias García Sebastián , Bermeo-Giraldo María Camila , Valencia-Arias Alejandro , Martínez Rojas Ezequiel , Aurora Vigo Edward Florencio , Gallegos Ada
Published: January 2025

Abstract* Financial literacy is one of the most important skills that people need in the 21st century, especially the youngest, as is the case with college students and mastering personal finance skills. This topic has gained importance in recent years in the field of scientific research. The objective of this study was to identify the most relevant factors related to financial education among young university students. A systematic literature review was developed based on the parameters established by the PRISMA statement. A total of 44 datasets were analyzed to identify the most recurring factors in the literature. Finally, the validity of the most relevant issues pertaining to the subject of study were identified. Thus, two themes were evident that are still valid and the most frequent in the literature on financial literacy among university students: financial behavior and financial knowledge. It is concluded that financial Inclusion, Budgeting, Financial Attitude, and Adolescents are other topics with a promising future in future research. The results of this study provide a structured guide for future research and help to identify research gaps that can be addressed in future studies.
Transformative social innovation and rural collaborative workspaces: assembling community economies in Austria and Greece
Authors: Stockdale Colm , Avdikos Vasilis
Published: January 2025

Background Collaborative Workspaces are rapidly growing and evolving across the world. Traditionally understood as an urban phenomenon, most research understands them as either ‘entrepreneurial-led’, as profit-driven and commercial spaces such as business incubators and accelerators, or ‘community-led’ as being bottom-up, not-for-profit ventures aimed at catering for the needs of their community. Recent years however have seen their diffusion beyond large urban agglomerations to small towns and villages, with their functions assumed to be more community-orientated. At the same time, social innovation, or social innovation processes have been gaining prominence in academia, policy, and practice, as they address societal problems and hold potential for new forms of social relations. This paper attempts to provide a novel framework towards understanding the transformative potential of rural collaborative workspaces, as they engage in processes of social innovation, by drawing from diverse and community economies literature and assemblage thinking. Methods The paper uses international case study comparison between rural Austria and Greece (One case from each country). Methods applied were: semi-structured interviews (N=28), participant observation and focus groups (2). Results Community-led rural collaborative workspaces hold transformative potential from i) their ability to assist rural actors with their capacities and realizing their desires and ii) changing individual subjectivities towards collective. Through changing social relations in praxis and perceptions, we examine how social innovation processes through collaborative workspaces can be understood as a means of opening new economic subjectivities towards creating community economies as their transformative potential. Conclusions Although rural collaborative workspaces hold potential for societal transformation, they require further institutionalization and support to move beyond the interstitial and symbiotic stages of transformation.
Macroeconomics. Country analysis workshop
Authors: Bazhenov Grigoriy , Belyakov Igor' , Biryukova Ol'ga , Bol'shakov Aleksandr , Bondarenko Kseniya , Gal'chenko Evgeniy , Gerasimova Yuliya , Gulenkov Il'ya , D'yachkova Dar'ya , Ivanova Mariya , Koptyaeva Ekaterina , Kupriyanov Aleksey , Lysenko Kirill , Makarova Ekaterina , Muhametov Oskar , Pil'nik Nikolay , Kamenchenko Kristina , Rudakov Maksim , Smolovik Elizaveta , Scherbakova Alina
Published: January 2025

The textbook is a collection of country examples illustrating macroeconomic models, as well as the conditions and practice of applying macroeconomic policy measures. Examples are provided on all key topics, from basic macroeconomic concepts to the current sustainable development agenda. At the end of each chapter, there is a list of questions for discussion in the seminar sessions, and at the end of the book there are sample test tasks for control.
The authors of the manual include staff from the National Research University Higher School of Economics and other universities, researchers from the Russian Academy of Sciences, as well as practitioners, including experts from the Central Bank of the Russian Federation, Bank Saint Petersburg, the Eurasian Fund for Stabilization and Development, the Center for Strategic Research, and others.
Meets the requirements of the latest generation of federal state educational standards for higher education.
For university students of economic specialties, as well as students of economic theory in non-economic specialties.
Spatial codes of key texts of Russian culture
Authors: Hayrullin Vladimir
Published: January 2025

The monograph examines the ways of representing open and closed spaces in such key texts of Russian classics as Leo Tolstoy's novel "Anna Karenina" and F.M. Dostoevsky's novel "The Idiot", and in the translations of these works into English. It is suggested that the spaces described using features encoding certain information about these spaces are presented differently by writers, and these differences become more pronounced when considering works translated into English, which allows us to talk about translation spatial codes. Much attention in the information field of the monograph is paid to the ways of representing the interior space of the "house" through a number of significant features. The study showed not only differences in the ways spaces are described, but also significant differences in attitudes towards open and sometimes stably enclosed spaces perceived as friendly or hostile.
It is intended for specialists in the field of theory and practice of translation and cultural studies, as well as undergraduates and postgraduates conducting research in these areas.
The history of veterinary legislation in Russia in the XVIII - early XX century.
Authors: Kolesnikov Vladimir , Svechnikova Larisa , Kolesnikova Viktoriya
Published: January 2025

For the first time in veterinary science, the monograph examines the history of veterinary medicine through its reflection in the legislation of the Russian state. Based on an extensive range of regulatory legal acts, many of which were first introduced into scientific circulation, the analysis of Russian legislation from the 18th century to the beginning of the 20th century was carried out, which allowed us to conclude about the role of the state and its legal institutions for veterinary medicine, veterinary education and veterinary science. For the first time, a systematic analysis of the sources of veterinary legislation has been carried out, and patterns of its formation and development have been identified. A number of new conclusions have been drawn about the fight against epizootics, sanitary and quarantine measures in Russia within the specified chronological framework.
For students, postgraduates and teachers of veterinary universities and faculties, specialists in the history of veterinary medicine and veterinary legislation, historians of law.
Investigative work of criminal investigation units (situational approach)
Authors: Glubokovskih Roman
Published: January 2025

The monograph examines the issues of the concept, content, and classification of investigative situations as one of the important categories of operational investigative science. The role of investigative situations in decision-making and in the development of problems of algorithmization of the investigative work of criminal investigation units is revealed.
It offers a description and solutions to situations that arise in the process of searching for persons who have fled from the bodies of inquiry, investigation and court, and missing persons.
It is intended for specialists in the field of operational investigative activities, criminology, law enforcement practitioners, teachers, graduate students (adjuncts), students (cadets).
First-episode psychosis requiring electroconvulsive therapy following SARS-CoV-2 infection – Description of two cases
Authors: Rodek Patryk , Alli-Balogun Barbara , Kucia Krzysztof
Published: January 2025

COVID-19 jest chorobą ogólnoustrojową. Od początku pandemii pojawiają się coraz liczniejsze doniesienia o neuropsychiatrycznych powikłaniach infekcji. Nadmierna odpowiedź zapalna w przebiegu infekcji powoduje zmiany w neuroprzekaźnictwie, które mogą skutkować między innymi niespecyficznym przebiegiem zaburzeń afektywnych i psychotycznych. Przedstawiamy opis dwóch przypadków dotychczas nieleczonych psychiatrycznie pacjentów, u których pierwszorazowy epizod psychotyczny wystąpił bezpośrednio po infekcji SARS-CoV-2. Elementem łączącym oba przypadki, oprócz poprzedzającej infekcji SARS-CoV-2, był niespecyficzny i niezwykle zmienny przebieg epizodu zaburzenia psychotycznego. Spowodowało to liczne trudności diagnostyczne oraz konieczność zmiany diagnozy w trakcie leczenia u obu pacjentów. U 58-letniej chorej początkowo rozpoznano uporczywe zaburzenia urojeniowe, a następnie organiczne zaburzenia afektywne, jednak ewolucja objawów spowodowała ostatecznie rozpoznanie ciężkiego epizodu psychotycznej depresji. W przypadku 68-letniego mężczyzny pierwotnie stwierdzona depresja psychotyczna okazała się pierwszorazowym epizodem schizofrenii o późnym początku. Z powodu znacznego nasilenia objawów oraz wyraźnej lekooporności wdrożono terapię elektrowstrząsową, po której uzyskano pełną remisję objawową i funkcjonalną. Pierwszorazowy epizod psychotyczny po COVID-19 to nowe, pojawiające się coraz częściej powikłanie infekcji, które pozostaje wciąż słabo zdefiniowane i opisane w literaturze. Wydaje się, że cechuje się istotnymi odmiennościami od dotychczas spotykanych jednostek chorobowych. Opisane przypadki podkreślają nieustanną potrzebę uwzględniania przebycia infekcji SARS-CoV-2 jako czynnika spustowego pierwszorazowych psychoz, gdyż może wpływać to zarówno na przebieg choroby, jak też na decyzje diagnostyczne i terapeutyczne.
Emotional and sleep disturbances among patients previously hospitalized due to COVID-19
Authors: Chatys-Bogacka Żaneta , Mazurkiewicz Iwona , Słowik Joanna , Słowik Agnieszka , Drabik Leszek , Wnuk Marcin
Published: January 2025

Cel pracy

Ocena częstości występowania zaburzenia emocjonalnych i snu (ESD) wśród pacjentów po COVID-19 wymagającym hospitalizacji, identyfikacja czynników predykcyjnych i poznanie ich wpływu na symptomy mgły mózgowej (BFS) oraz jakość życia w pracy (QWL).

Metoda

Pacjenci ≥18 lat retrospektywnie raportowali obecność objawów z zakresu ESD (smutek, lęk, niepokój, bezsenność, nadmierna senność w ciągu dnia, koszmary senne) i BFS oraz oceniali QWL przed COVID-19 i w ciągu 0-4, 4-12 i >12 tygodni po infekcji za pomocą poddanego walidacji kwestionariusza w wersji papierowej lub internetowej. Zebrano dane dotyczące wieku, płci, chorób współistniejących, leczenia przed przyjęciem oraz wyników badań laboratoryjnych. Do badania ostatecznie włączono 181 pacjentów (średni wiek 56,02+-13,02 lat, kobiety 37,02%).

Wyniki

COVID-19 zwiększał 1,6 do 2,2-krotnie zapadalność na ESD w ciągu 0-4, 4-12 i >12 tygodni od infekcji (odpowiednio 66,85%, 60,77% i 50,28%). W analizie wieloczynnikowej, predyktorem nowo powstałych ESD po COVID-19 było stężenie hemoglobiny w ostrej fazie infekcji (OR 0,64, 95%CI: 0,50-0,80 na 1g/L, p=0.001). U pacjentów z istniejącymi wcześniej i nowopowstałymi ESD, COVID-19 zwiększał ryzyko występowania BFS odpowiednio 1,9 i 3,9-krotnie >12 tygodni od infekcji. Pogorszenie QWL >12 tygodni po COVID-19 było związane z wiekiem (OR 0,62, 95%CI:0,37-0,73 na 10 lat, p<0,001), płcią żeńską (OR 3,47, 95%CI:1,40-8,56, p=0,007), występującymi wcześniej (OR 21,58, 95%CI:2,57-181,30, p=0,005) i nowopowstałymi ESD (OR 30,88, 95%CI:3,85-247,90, p=0,001).

Wnioski

Większość pacjentów po COVID-19 cierpi na objawy z kręgu ESD, których predyktorem jest stężenie hemoglobiny. ESD zwiększają ryzyko współistnienia BFS. ESD, szczególnie smutek, niepokój, bezsenność i nadmierna senność w ciągu dnia, silnie wpływają na QWL >12 tygodni po COVID-19.
Uso de Edpuzzle en la enseñanza y aprendizaje de costos.
Authors: Ortiz-Cea Vesnia , Colmenárez Mendoza Alexis
Published: January 2025

Uno de los grandes desafíos de los docentes universitarios al adaptar sus clases
presenciales a virtuales es la creación de recursos multimedia para aprendizajes online que
permitan continuar con el proceso de formación profesional del alumnado. La creación de videos
para las clases asincrónicas es una opción que muchos escogen, sin embargo, esta herramienta
puede ser aún más eficaz si se agrega la interactividad, es aquí donde aplicaciones como
Edpuzzle se convierten en una alternativa considerable pues permite añadir preguntas a videos
para hacerlos interactivos. En el presente trabajo se da a conocer el proceso de implementación
de Edpuzzle, para la enseñanza de contabilidad de costes (c-costes) en la formación de
estudiantes de la carrera de Ingeniería Comercial (IComer) en una universidad estatal. El estudio
de diseño descriptivo, permitió obtener la opinión de 72 estudiantes frente a la metodología de
clase empleada. Tras la experiencia, se concluye que es una estrategia útil y eficaz para emplear
en clases asincrónicas y presenciales, ya que permite al estudiante interiorizar y comprender mejor
los contenidos, participar activamente de las clases y recibir la retroalimentación inmediata por
parte del docente.
EL HIMNO DE ANDALUCÍA COMO SÍMBOLO DE UNIÓN DESDE LA TRANSICIÓN HASTA NUESTROS DÍAS.
Authors: Diéguez García José María
Published: January 2025

El Himno de Andalucía es uno de los símbolos más representativos de la identidad
cultural y sociopolítica de la comunidad autónoma de Andalucía. Su relevancia en la
sociedad andaluza ha crecido desde su presentación en el mitin del PSA-PSP celebrado
en el año 1977. Su posterior adopción oficial en 1981, tras la aprobación del Estatuto de
Autonomía, supuso la oficialidad de un símbolo que proporcionó cohesión tanto social
como cultural. Aunque su historia y significación se remontan a las primeras décadas
del siglo XX, en el contexto de los movimientos regionalistas y nacionalistas en España,
mantiene hoy día un importante lugar dentro de la sociedad andaluza. Este artículo
explora la importancia del Himno de Andalucía en la configuración de la identidad
andaluza, su simbolismo, y su papel en la cohesión social y política de la región.
Teoría de las ideas según G.B. Vico.
Authors: Acri Francesco
Published: January 2025

En este discurso, F. Acri, con un estilo claro, didáctico y personal, comenta los textos de Vico
en los que se fundamentan sus tres teorías sobre las ideas: una que las presenta como paradigmas o arquetipos, otra como asociaciones de elementos, y otra, la de la Idea única en forma teológica, la más “viquiana”
según el autor, por ser la mejor explicada y aplicada. Las tres surgen y se mantienen en paralelo a lo largo
de toda la obra del napolitano, reflejando su ideología, sus dudas, sus contradicciones, y las posibles conciliaciones entre ellas para comprender las sabidurías divina, heroica y humana.
Understanding Users’ Content Contribution Behavior When Knowledge Can Be Priced
Authors: Cong Ziwei , Zhao Ying , Zhang Zilei
Published: January 2025

We find that allowing creators to produce paid content (e.g., paid live sessions) rekindles their declining motivation to contribute free content in specialized domains.
Cultural Homophily and Collaboration in Superstar Teams
Authors: Békés Gábor , Ottaviano Gianmarco I. P.
Published: January 2025

One may reasonably think that cultural homophily, defined as the tendency to associate with others of similar culture, affects collaboration in multinational teams in general but not in superstar teams of professionals at the top of their industry. The analysis of an exhaustive data set on the passes made by professional European football players in the top five men’s leagues reveals that on the contrary, cultural homophily is persistent, pervasive, and consequential, even in superstar multinational teams of very-high-skill individuals with clear common objectives and aligned incentives who are involved in interactive tasks that are well defined and not particularly culture intensive.

This paper was accepted by Olav Sorenson, organizations.

Funding: G. Békés thanks the Hungarian Academy of Sciences [Grant “Firms, Strategy and Performance” Lendület] for support.

Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.01799 .
Revealed Wisdom of the Crowd: Bids Predict Loan Quality
Authors: Yao Jiayu , Lin Mingfeng , Wu D. J.
Published: January 2025

Despite the popularity of the phrase “wisdom of the crowd,” not all crowds are wise because not everyone in them acts in an informed, rational manner. Identifying informative actions, therefore, can help to isolate the truly wise part of a crowd. Motivated by this idea, we evaluate the informational value of investors’ bids using data from online, debt-based crowdfunding, in which we were able to track both investment decisions and ultimate repayment statuses for individual loans. We propose several easily scalable variables derived from the heterogeneity of investors’ bids in terms of size and timing. We first show that loans funded with larger bids relative to the typical bid amount in the market or to the bidder’s historical baseline, particularly early in the bidding period, are less likely to default. More importantly, we perform theory-driven feature engineering and find that these variables improve the predictive performance of state-of-the-art models that have been proposed in this context. Even during the fundraising process, these variables improve predictions of both funding likelihood and loan quality. We discuss the implications of these variables, including loan pricing in secondary markets, crowd wisdom in different market mechanisms, and financial inclusion. Crowdfunding platforms can easily implement these variables to improve market efficiency without compromising investor privacy.

This paper was accepted by David Simchi-Levi, information systems.

Funding: We gratefully acknowledge the financial support of the Business Analytics Center in the Scheller College of Business and the Ewing Marion Kauffman Foundation.

Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.02575 .
Can Socially Minded Governance Control the Artificial General Intelligence Beast?
Authors: Gans Joshua S.
Published: January 2025

This paper robustly concludes that it cannot. A model is constructed under idealized conditions that presume that the risks associated with artificial general intelligence (AGI) are real, that safe AGI products are possible, and that there exist socially minded funders who are interested in funding safe AGI, even if this does not maximize profits. It is demonstrated that a socially minded entity formed by such funders would not be able to minimize harm from AGI that unrestricted products released by for-profit firms might create. The reason is that a socially minded entity can only minimize the use of unrestricted AGI products in ex post competition with for-profit firms at a prohibitive financial cost and so, does not preempt the AGI developed by for-profit firms ex ante.

This paper was accepted by Maria Guadalupe, business strategy.
Grey areas in restorative dentistry: Part 3. clinical decision making and care planning
Authors: Caplin Robert L
Published: January 2025

Much of clinical dentistry is subjective rather than objective, and every dental practitioner must make decisions about how to manage the various clinical and ethical challenges that patients present. These clinical decisions are ultimately idiosyncratic and are, therefore, the reason that there can be wide variation between dentists as to how each would manage a particular situation. There is a need to balance the demands of the patient with the ethical requirements of the profession and the moral position of the practitioner.

CPD/Clinical Relevance: Whereas some aspects of dentistry are supported by science and the evidence base, many are not, especially in the realm of clinical decision making.
Phase Change Materials Promise Boost for Decarbonised Heat
Authors: Ford Jason
Published: January 2025

Water-based heat storage improved with addition of PCMs
John Fowler: Mastermind of The London Underground
Authors: Smith Nick
Published: January 2025

One of the great Victorians, Sir John Fowler is best remembered for two feats of engineering separated by a quarter of a century: London’s Metropolitan Railway and the Forth Bridge.
Learned Volterra models for nonlinearity equalization in wavelength-division multiplexed systems
Authors: Salgado Nelson Castro , Boscolo Sonia , Ellis Andrew , Sygletos Stylianos
Published: January 2025

Multichannel digital equalization has proved capable of mitigating fiber-induced inter-channel impairments which constitute a main limitation in wavelength-division multiplexed systems. In this paper, we present three multiple-input-multiple-output learned equalization architectures based on the inverse Volterra series transfer function (IVSTF): a fully parallel frequency-domain approach (L-IVSTF), a field-enhanced version with improved adaptability (FE L-IVSTF), and a time-domain implementation (L-simIVSTF). We demonstrate that machine-learning optimization enables efficient multichannel equalization for all the structures, with the 9 x 9 L-simIVSTF and FE L-IVSTF equalizers achieving an average signal-to-noise ratio improvement of 2.2 dB over chromatic dispersion compensation. The three models are thoroughly characterized and compared in terms of performance and computational cost, pinpointing the FE L-IVSTF as the model with the best trade-off.
Chega, racism and nativism in Portugal: An interview with Isabel David and Samuel de Paiva Pires
Authors: Kelly Deirdre
Published: January 2025

Chega, a populist radical-right political party founded in 2019, has swiftly gained prominence in Portugal, challenging the notion of Portuguese exceptionalism in resisting populist radical-right ideologies. In this interview, political scientists Isabel David, an associate professor at the University of Lisbon specializing in populism and Turkish politics, and Samuel de Paiva Pires, a visiting assistant professor at the same institution with expertise in political theory, especially liberalism and conservatism, discuss the rise of the populist radical-right in Portugal, focusing on Chega’s discursive strategies. Drawing on their co-authored article ‘Racism and nativism in the discourse of Chega party in Portugal’ (co-authored with Pedro Moreira da Fonseca), they explore how Chega has instrumentalized racism and nativism to build its voter base in a country long considered resistant to the populist radical-right trend seen across Europe. The scholars analyse Chega’s strategic framing in relation to three key cognitive mechanisms: the opposition between in-group and out-groups, blame attribution and emotional triggers. They argue that the Roma community is a primary target of Chega’s specific brand of racism and nativism, with the party positioning this group as a central out-group in its rhetoric. David and de Paiva Pires reflect on the role of identity politics and the broader implications of Chega’s rise for Portugal’s political landscape and in relation to other populist radical-right movements in Europe and internationally. David and de Paiva Pires were interviewed by Deirdre Kelly, a lecturer at Technological University Dublin, on 26 August 2024. This interview has been edited for length and clarity.
Football and Fascism: The Politics of Popular Culture in Portugal, Rahul Kumar (2023)
Authors: Serapiglia Daniele
Published: January 2025

Review of: Football and Fascism: The Politics of Popular Culture in Portugal, Rahul Kumar (2023)

Berlin and Boston, MA: De Gruyter, 265 pp.,

ISBN 978-3-11072-122-5, h/bk, €129.00

ISBN 978-3-11072-150-8, e-book, €129.00
Encounters with Jazz on Television in Cold War Era Portugal, Pedro Cravinho (2022)
Authors: Lopes Sofia Vieira
Published: January 2025

Review of: Encounters with Jazz on Television in Cold War Era Portugal, Pedro Cravinho (2022)

New York and Milton Park: Routledge, 202 pp.,

ISBN 978-0-36748-904-5, p/bk, £39.99

ISBN 978-0-36748-904-5, h/bk, £135.00

ISBN 978-0-36748-904-5, e-book, £35.99
Introduction: ‘The Rise of the Far Right in Spain and Portugal’: A new chapter in Iberian politics?
Authors: Kelly Deirdre , Pujol Anton
Published: January 2025

This introductory article to the Special Issue on ‘The Rise of the Far Right in Spain and Portugal’, explores the far right’s ascent in the two countries within a broader European and global context, where nationalist and populist movements have gained significant momentum. It provides a brief overview of far-right politics in both countries and traces the legacy of authoritarian regimes under Franco in Spain and Salazar in Portugal. It examines the contemporary resurgence of far-right parties, such as Vox and Se Acabó la Fiesta (SALF) (‘The party is over’) in Spain and Chega in Portugal. The analysis explores the sociopolitical factors driving this phenomenon, including economic anxiety, national identity concerns, and reactions against globalization and immigration, and compares the factors driving the emergence of these parties in the two countries. The article introduces the chapters and interviews that follow. The introduction concludes by considering the implications of this far-right ascendancy for the future of democracy and political stability in the Iberian peninsula and beyond.
Mohssine, A. y Rodríguez, S. (ed.) (2023). "Figuraciones del mal en las creadoras hispánicas contemporáneas", Sevilla, Editorial Álfar.
Authors: Loeza Zaldivar Alejandro
Published: January 2025

Reseña del libro Mohssine, A. y Rodríguez, S. (ed.) (2023). Figuraciones del mal en las creadoras hispánicas contemporáneas, Sevilla, Editorial Álfar, 296 pp, ISBN: 9788478989508.
Ilian, I. y Šabec, M. (2024). "Pablo Neruda en el espejo del socialismo". Bruselas: Peter Lang Verlag.
Authors: Sánchez Pablo
Published: January 2025

Reseña del libro Ilian, I. y  Šabec, M. (2024). Pablo Neruda en el espejo del socialismo. Bruselas: Peter Lang Verlag, 432 pp, ISBN: 9783034349055
Bone remodeling parameters in patients with type 1 diabetes mellitus and diabetic peripheral polyneuropathy of varying severity
Authors: Timkina N. V. , Murasheva A. V. , Ustyuzhanina A. O. , Radugin F. M. , Chernikova A. T. , Vasilieva E. Yu. , Karonova T. L.
Published: January 2025

BACKGROUND: Diabetic peripheral polyneuropathy (DPPN) is a common and early chronic complication of diabetes mellitus (DM). This complication can be associated with bone tissue damage and low-trauma fractures, particularly in type 1 DM. Therefore, evaluating the relationship between DPPN and bone metabolism parameters is crucial for clinical practice.

AIM: To assess bone remodeling parameters in patients with type 1 DM with varying degrees of DPPN.

MATERIALS AND METHODS: The study included 90 patients with type 1 DM and DPPN aged 18 to 55 years on stable insulin therapy for the past 3 months. Assessment was conducted for levels of HbA1c, 25(OH)D, total calcium (Ca), phosphorus (P), parathyroid hormone (PTH), osteocalcin (OC), C-terminal telopeptide of type I collagen (CTX), fibroblast growth factor 23 (FGF-23) in serum. The degree of neurological deficit was determined using the Neuropathy Disability Score (NDS), Neuropathy Symptoms Score (NSS), and Michigan Neuropathy Screening Instrument (MNSI). Dual-energy X-ray absorptiometry (DXA) was performed to determine bone mineral density (BMD) and trabecular bone score (TBS).

RESULTS: Regardless of the degree of DPPN severity, patients with type 1 DM were comparable in HbA1c and 25(OH)D levels. A direct correlation was found between the severity of neurological disorders and BMI (r=0.214; p=0.044) and duration of DM (r=0.246, p=0.019). Vitamin D insufficiency and deficiency were diagnosed in 79% of examined patients with type 1 DM, but the level of 25(OH)D in serum did not depend on the degree of DPPN severity, HbA1c level, duration of DM, and daily insulin dose (p>0.05). A positive correlation was established between PTH level and severity of neurological symptoms, and a ­negative one with HbA1c level. Patients with type 1 DM and varying degrees of DPPN did not differ in BMD and TBS. A Z-score of less than -2.0 SD was only recorded in six patients, and partially degraded microarchitecture of bone tissue was observed in 8 patients.

CONCLUSION: Therefore, BMD, TBS, and bone remodeling markers in patients with type 1 DM and DPPN were independent of the degree of neurological deficit, degree of compensation, and duration of DM. Vitamin D deficiency is common in most patients with type 1 DM, but the 25(OH)D level is not influenced by HbA1c level, duration of the disease, and daily insulin dose.
AUTENTIKASI ALAT BUKTI ELEKTRONIK DALAM MEMPERLANCAR PEMBUKTIAN DI PERSIDANGAN PADA ERA DISRUPSI
Authors: Dewantoro Dewantoro
Published: January 2025

Pembuktian di persidangan untuk mencari kebenaran baik materil dan formil tidak sesederhana seperti dahulu lagi. Penggunaan alat bukti elektronik mulai dipergunakan untuk membuktikan fakta-fakta yang rumit, hal ini menjadi dilema bagaimana caranya agar hakim yakin bahwa alat bukti elektronik dapat menjelaskan tentang peristiwa apa yang terjadi sebenarnya, olehkarena itu diperlukan rambu-rambu aturan atau petunjuk teknis agar alat bukti elektronik dapat digunakan dan meyakinkan hakim akan kebenaran suatu peristiwa. Kesimpulan dari penulisan ini pemerintah sudah menyediakan rambu-rambu teknis dan sekarang perlu pengetahuan dan keterampilan masyarakat atau penegak hukum agar dapat mengoperasionalkannya di persidangan dan menghasilkan hasil pembuktian yang autentik dan dapat diterima oleh hakim sebagai bahan pertimbangan pengambilan putusan pengadilan atau penetapan hakim.
Memperkuat Pertahanan Laut Indonesia: Belajar dari Strategi Pertempuran Laut Rusia-Jepang, 1904-1905
Authors: Hidayat Cecep
Published: January 2025

The Russo-Japanese War (1904-1905) was a significant event in the early 20th century that saw the two nations clash on various battlefields, both on land and at sea. This article aims to analyze the naval combat strategies employed during the Russo-Japanese War, with the objective of providing relevant insights for the Indonesian Navy (TNI AL). The primary focus of this analysis is the effectiveness of strategies such as naval blockades, visionary leadership, and the optimization of fleets and logistics, factors that are highly relevant for strengthening Indonesia’s maritime defense as an archipelagic nation. This article is based on a historical research approach, utilizing a variety of sources, including archives, books, magazines, journal articles, and other documents that contain pertinent information on the topic. The analysis reveals that six naval battles took place during the Russo-Japanese War, with Japan emerging victorious in five of them. In these battles, Japan implemented an aggressive naval blockade strategy, supported by effective leadership, a superior fleet and armament, as well as a well-organized logistics system. Based on these findings, the researcher recommends that the TNI AL develop a naval combat operation plan tailored to Indonesia’s specific maritime conditions, in order to strengthen its deterrent capabilities and national maritime defense.