bluuebunny/crossref_metadata_2025 huggingface dataset:
Reducing Clinical Trial Monitoring Resources and Costs With Remote Monitoring: Retrospective Study Comparing On-Site Versus Hybrid Monitoring
Authors: Fu Zhiying , Liu Xiaohong , Zhao Shuhua , Yuan Yannan , Jiang Min
Published: June 2023

Background

Clinical research associates (CRAs) monitor the progress of a trial, verify the data collected, and ensure that the trial is carried out and reported in accordance with the trial protocol, standard operating procedures, and relevant laws and regulations. In response to monitoring challenges during the COVID-19 pandemic, Peking University Cancer Hospital launched a remote monitoring system and established a monitoring model, combining on-site and remote monitoring of clinical trials. Considering the increasing digitization of clinical trials, it is important to determine the optimal monitoring model for the general benefit of centers conducting clinical trials worldwide.

Objective

We sought to summarize our practical experience of a hybrid model of remote and on-site monitoring of clinical trials and provide guidance for clinical trial monitoring management.

Methods

We evaluated 201 trials conducted by our hospital that used on-site monitoring alone or a hybrid monitoring model, of which 91 trials used on-site monitoring alone (arm A) and 110 used a hybrid model of remote and on-site monitoring (arm B). We reviewed trial monitoring reports from June 20, 2021, to June 20, 2022, and used a customized questionnaire to collect and compare the following information: monitoring cost of trials in the 2 models as a sum of the CRAs’ transportation (eg, taxi fare and air fare), accommodation, and meal costs; differences in monitoring frequency; the number of monitored documents; and monitoring duration.

Results

From June 20, 2021, to June 20, 2022, a total of 320 CRAs representing 201 sponsors used the remote monitoring system for source data review and the verification of data from 3299 patients in 320 trials. Arm A trials were monitored 728 times and arm B trials were monitored 849 times. The hybrid model in arm B had 52.9% (449/849) remote visits and 48.1% (409/849) on-site visits. The number of patients’ visits that could be reviewed in the hybrid monitoring model increased by 34% (4.70/13.80; P=.004) compared with that in the traditional model, whereas the duration of monitoring decreased by 13.8% (3.96/28.61; P=.03) and the total cost of monitoring decreased by 46.2% (CNY ¥188.74/408.80; P<.001). These differences were shown by nonparametric testing to be statistically significant (P<.05).

Conclusions

The hybrid monitoring model can ensure timely detection of monitoring issues, improve monitoring efficiency, and reduce the cost of clinical trials and should therefore be applied more broadly in future clinical studies.
The Importance of Gender-Neutral Terminology in Risk Evaluation and Mitigation Strategy Programs: A Call to Action
Authors: Burnette Colin , Smithy William , Strock Daniel , Sivesind Torunn E , Dellavalle Robert
Published: June 2023

The use of risk evaluation and mitigation strategy (REMS) programs is frequently required for prescriptions with potentially teratogenic effects, especially in the field of dermatology. Among these REMS programs, the most well-known example is isotretinoin, an oral retinoid that uses the iPLEDGE system. iPLEDGE has strict regulations and a lengthy approval process, and until recently, patients were grouped into 3 categories: male, female, or female of reproductive potential. This strict grouping has posed problems in the medical community, especially for gender-diverse individuals where their perceived gender conflates with their assigned grouping causing patient-specific distress. The distinction between gender—a multifactorial perception of identity—and biological sex is addressed under new iPLEDGE guidelines. Dermatologists now register patients under one of 2 categories: patients who can become pregnant and those who cannot become pregnant. This change simultaneously improves the accessibility to isotretinoin among gender-diverse individuals, while limiting prescription barriers. Despite initial success being limited due to lengthy system conversions, a registration process based on reproductive potential ultimately enhances iPLEDGE’s goal to prevent potential birth defects. We propose that other REMS programs follow the standard set by the iPLEDGE system, including those for the medications thalidomide, acitretin, and mycophenolate mofetil, all of which currently have a similar taxonomy to that of the old iPLEDGE system. Implementing the standardization of gender-neutral terminology can maximize enrollment and minimize distress. Current and ongoing refinement of iPLEDGE and other REMS is needed to build protocols solely around the prevention of birth defects without regard to sex or gender.
Clinical Accuracy of Large Language Models and Google Search Responses to Postpartum Depression Questions: Cross-Sectional Study (Preprint)
Authors: Sezgin Emre , Chekeni Faraaz , Lee Jennifer , Keim Sarah
Published: June 2023

UNSTRUCTURED

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Designing and Validating a Survey for National-Level Data During the COVID-19 Pandemic in Sri Lanka: Cross-Sectional Mobile Phone Surveys (Preprint)
Authors: Phadnis Rachael , Perera Udara , Lea Veronica , Davlin Stacy , Lee Juliette , Siesel Casey , Abeygunathilaka Dhanushka , Wickramasinghe S C
Published: June 2023

BACKGROUND

The COVID-19 pandemic has generated a demand for timely data, resulting in a surge of mobile phone surveys for tracking the impacts of and responses to the pandemic. Mobile phone surveys have become a preferred mode of data collection across low- and middle-income countries.

OBJECTIVE

This study piloted 2 population-based, cross-sectional mobile phone surveys among Sri Lankan residents in 2020 and 2021 during the COVID-19 pandemic. The surveys aimed to gather data on knowledge, attitudes, and practices, vaccine acceptability, availability, and barriers to COVID-19 testing, and use of a medicine distribution service.

METHODS

The study used Surveda, an open-source survey tool developed by the NCD (noncommunicable disease) Mobile Phone Survey Data 4 Health Initiative, for data collection and management. The surveys were conducted through interactive voice response using automated, prerecorded messages in Sinhala, Tamil, and English. The sample design involved random sampling of mobile phone numbers, stratified by sex, proportional to the general population. Eligibility criteria varied between surveys, targeting adults aged 35 years and older with any noncommunicable disease for the first survey and all adults for the second survey. The data were adjusted to population estimates, and statistical analysis was conducted using SAS (SAS Institute) and R software (R Core Team). Descriptive statistics, Rao-Scott chi-square tests, and z tests were used to analyze the data. Response rates, cooperation rates, and productivity of the sampling approach were calculated.

RESULTS

In the first survey, n=5001, the overall response rate was 7.5%, with a completion rate of 85.6%. In the second survey, n=1250, the overall response rate was 10.9%, with a completion rate of 61.9%. Approximately 3 out of 4 adults reported that they avoided public places (888/1175, 75.6%), more than two-thirds avoided public transportation (808/1173, 68.9%), and 9 out of 10 practiced physical distancing (1046/1167, 89.7%). Approximately 1 out of 10 Sri Lankan persons reported being tested for COVID-19, and the majority of those received a polymerase chain reaction test (112/161, 70%). Significantly more males than females reported being tested for COVID-19 (98/554, 17.8% vs 61/578, 10.6%, respectively; P<.001). Finally, the majority of adult Sri Lankan people reported that they definitely or probably would get the COVID-19 vaccination (781/1190, 65.7%).

CONCLUSIONS

The surveys revealed that, overall, the adult Sri Lankan population adhered to COVID-19 mitigation strategies. These findings underscore the use of mobile phone surveys in swiftly and easily providing essential data to inform a country’s response during the COVID-19 pandemic, obviating the need for face-to-face data collection.
A Research on Identity Negotiation of Chinese Overseas Students
Authors: Bi Wentong
Published: June 2023

In the interpretative paradigm, it’s believed that culture can be reflected in people’s behaviors in their identity negotiation processes. In this course paper, the identity negotiation processes of three Chinese overseas students are analyzed with the guidance of Identity Negotiation Theory. Based on the five themes of identity dialectics, the researcher designed semi-structured interviews and collected data from the three interviewees. And the analysis is also carried out from the five themes in identity dialectics. But there are also some limitations in this paper as well to be further improved.
Time Series Analysis of Philippine Agricultural Rice Productivity using Cobb-Douglas Production Function from 2017 To 2022
Authors: H. Daproza Giselle , M. Dominguez Maria Lourdes , C. Esguerra Myrell Ann , E. Gonzales Jocelyn , B. Cruz Jocelyn
Published: June 2023

One of the main agricultural industries in the Philippines, particularly in Central Luzon, has been rice production. This study investigated the influences and determinants on national rice production. Labor, capital, credit to agriculture, spending, irrigated areas, land, and fertilizer are the relevant factors. The Cobb-Douglas Production Function was used in the study. The relationship between production output and production inputs (factors) is modeled by the Cobb-Douglas Production Function. It is used to calculate ratios of inputs to one another for efficient production and to estimate the technological change in production methods. It measured the elasticity, marginal rate of contribution, and marginal returns of capital, labor, fertilizer, irrigation, production loan, farm area, and government spending to the total agricultural rice productivity of the Philippines. This paper also analyzed the production in terms of its input and output and estimated the relationship between each input and output. The results of this study showed that capital, expenditure, and land do not significantly affect the volumes of production of rice. While labor, credit to agriculture, irrigated areas, and fertilizer significantly affect the volume of production of rice.
Exploring the Influence of Absorptive Capacity on Innovation: An Empirical Study of Large Industrial Companies in Syria
Authors: Bahlawan Abd Al Azez Al
Published: June 2023

This paper investigates the impact of absorptive capacity on exploratory innovation in large industrial companies in Syria. The study employs a sample of 278 managers, and utilizes multiple regression analysis for the investigation. The results reveal a significant positive relationship between absorptive capacity and exploratory innovation. These findings highlight the importance of absorptive capacity as a strategic tool for enhancing exploratory innovation, and offer valuable insights for managers and policy-makers in industries facing dynamic and complex environments.
The Influence of Capability-Supportive Culture on Alliance Performance: A Study of Small Industrial Sector Managers in Syria
Authors: Bahlawan Abd Al Azez Al
Published: June 2023

This study explores the impact of Capability-Supportive Culture (CSC) on alliance performance among small industrial sector managers in Syria. Employing a sample of 189 managers, the study uses a quantitative approach, leveraging a survey methodology and regression analysis to assess the relationship. The findings indicate a significant positive relationship between a capability-supportive culture and alliance performance. These insights contribute to the understanding of cultural determinants of alliance performance and have practical implications for managerial practice in the small industrial sector.
Adoptive Motherhood in India: An Analysis Through Myths and Critical Theories
Authors: Dey Dr. Arpita
Published: June 2023

Motherhood, biological or otherwise, is exclusively dedicated to the nurturance of children. The experience of motherhood, institutionalized and ghettoized under patriarchy, has often been subjected to the systematic massacring of female potentialities (Rich 13). History has been a witness to the making of biological mothers—sometimes without a choice of their own and the mothering capacities of women are often applauded based on their birthing capacities. What, therefore, becomes unnoticed in the array of societal expectations, is the trials and tribulations of the women in general, to fulfil the normative criteria of biological motherhood. As motherhood becomes a sacred calling for most women, the desire for a genetic child gets strengthened in the maternal psyche. And the (in)capability to further the species through biological reproduction makes the women discover other avenues for fulfilling this prefixed maternal capacity. This paper is an attempt to explore the various mythologies surrounding adoptive motherhood and mothering in India while deciphering the feminist analysis of the practice of adoptive mothering and its importance for maintaining the sanctity of motherhood in general.
The Impact of English Movies with Standard Subtitles on Enhancing the Writing Skills of EFL Students at Cihan University – Duhok
Authors: Omar Khadija Saleem , Salman Nahida Mohammed , Vadivel Balachandran
Published: June 2023

This research paper aims to comprehensively investigate the effects of English movies accompanied by standard English subtitles on the writing skills of English as a second language (ESL) learners. Writing, considered a particularly challenging language skill, presents unique difficulties for ESL learners. Moreover, understanding English movies without subtitles poses further challenges. To address these issues, integrating media and movies into language learning practices has been recognized as highly effective. This study employs a meticulously designed questionnaire as the primary research instrument to collect data from a sample size of 30 participants aged 19-24 enrolled at Cihan University- Duhok. A combination of qualitative and quantitative methodologies is utilized to thoroughly examine the impact of watching English movies with English subtitles on the development of writing skills. Participants provide valuable insights into the effects they experience when utilizing subtitles, including improvements in expressive abilities, as well as the formation of more coherent and sophisticated sentences and phrases. The findings unequivocally demonstrate that a significant majority of participants attribute their enhanced writing skills to the use of English movies with subtitles as a powerful learning tool.
Investigating the Effectiveness of ESL Games and Activities in Developing Listening Skills among ESL Learners
Authors: Abdulateef Yousif Raed , Mustafa Abdulrzaq Nizar , Haji Ahmed Ali , Abdullah Ari Khalid , Vadivel Balachandran
Published: June 2023

This study aimed to examine the efficacy of using ESL games and activities to enhance ESL learners' listening skills. The study was conducted with participants of 75 from various universities in Kurdistan Region, selected using a stratified random sampling method. The pretest-posttest control group design was employed in this study, in which the experimental group received ESL games and activities, while the control group received traditional listening instruction. Data analysis was performed using descriptive statistics, independent t-tests, and ANCOVA. The findings of the study revealed that the experimental group outperformed the control group on the post-test, indicating that ESL games and activities had a significant impact on the development of listening skills among ESL learners. This study’s outcomes have several implications for teaching and learning practices. Instructors and curriculum designers could integrate ESL games and activities into their teaching methodologies to make language learning more engaging and interactive. Furthermore, learners could benefit from a more enjoyable and dynamic learning experience. The study’s limitations were that it was conducted in a specific cultural and educational context, which may limit its generalizability. Additionally, the study did not consider individual differences among participants, such as prior language proficiency or motivation levels, which may have influenced the results. In conclusion, this study indicates that ESL games and activities can enhance listening skills among ESL learners. Future research could explore the effectiveness of these methods in different educational settings and with different populations of ESL learners.
Composición corporal y su percentil: una pequeña historia del uso de la fórmula de Quételèt en antropometría
Authors: Badillo Muñoz Martha Ivonne
Published: June 2023

La evaluación del crecimiento y del desarrollo físico es uno de los aspectos que conforma la práctica clínica en la atención a pacientes, por la relación existente entre el crecimiento y el estado de salud en un individuo. Con la finalidad de tener datos confíales, la antropometría es un indicador que tiene como propósito la cuantificación de las variaciones en las dimensiones físicas y de la composición del cuerpo humano en diferentes edades incluyendo el estado de nutrición. Con ese propósito y como parte de las propuestas para la medición se realiza en este artículo un breve recorrido histórico de la conformación de la fórmula de Quételèt y su uso en el ámbito clínico. Aunque muchos autores mencionan que el IMC no mide la grasa corporal directamente, si encuentran la correlación moderadamente con medidas más directas de la grasa corporal. Además, de que el IMC parece estar correlacionado con diferentes resultados metabólicos y de enfermedades no trasmisibles.
Catalog and distribution atlas of the Scarabaeoidea (Insecta: Coleoptera) of El Salvador
Authors: Pablo-Cea José D. , Cave Ronald D. , Serrano-Peraza Francisco A. , Alvarado-Larios Raquel , Deloya Cuauhtémoc , Serrano-Chicas Katerin A. , Alfaro Elizabeth , Chinchilla-Rodríguez Abizai C. , Girón-Segovia Daniel , Noriega Jorge Ari
Published: June 2023

Less than 1% of the literature on El Salvador’s biodiversity is about terrestrial invertebrates, which limits our knowledge of this group’s diversity, richness, and distribution in the territory. Scarabaeoidea are megadiverse in multiple ecosystems and perform many functions. This work aims to catalog the Scarabaeoidea in El Salvador. We conducted an exhaustive review of published literature and reviewed numerous entomological collections with relevant material. Maps were constructed to visualize the known distribution of each species in the country. There are 295 scarab beetle species (including 19 new country records) representing 106 genera in 7 families in El Salvador. Six precinctive species are known. Twenty-two species are discarded as occurring in El Salvador, either because they are not valid species or because of misidentifications or dubious records. This work is the first approach to knowing the Scarabaeoidea in El Salvador, a territory that is usually considered of no importance for the conservation of regional biodiversity due to its small area, high rate of deforestation, and overpopulation. The results of this work reinforce the need for biological prospecting in the territory to know, conserve, and protect the remaining biodiversity.
Accident/RTO/Abandoned Vehicle Investigation Using QR Code on Vehicle
Authors: Agawane Pratik
Published: June 2023

Abstract: In India fatal road traffic accidents constitute a significant public health problem in many countries around the world. In Saudi Arabia, road accidents are one of the leading causes of death. The delay in detecting and caring for people who have been exposed to traffic accidents increases the risk of injuries. Injury care after the accident is severely affected by time; a few minutes may separate life from death. Several solutions have been proposed to reduce the incidence of accidents or to reduce the mortality rate at a high financial cost. Recent approaches are using built-in vehicle accident notification system. While these approaches work in pleasing manner, they are expensive, maintenance complex task, and are not available in all cars. However, there is a lack of methods and solutions used to detect the rapid occurrence of accidents and thus speed in transfer of patients to medical centres. In this project we are providing solution for betterment of traffic accident management The various uses we are providing are vehicle identification, in case of accident to identify the victim in case of vehicle stolen-using chasse number, etc. we are using QR code to make the users documents secure. QR Codes have fast response time and have large storage capacity, QR Codes can be used perfectly to send encrypted data (messages) to the receiver. In user panel, user will upload documents after submission the verification takes place in verification panel then the verified user will be given the unique QR code. At the signal, traffic police will scan the QR code and get all the documents of the respective user. So this system will provide a smart and easy way of verification of documents and identifying the user in accident management system
Dynamic Resource Allocation in Cloud Environments
Authors: Nair Rohith Sunilkumar
Published: June 2023

Abstract: The provisioning and use of computing resources has been completely transformed by cloud computing, which provides previously unheard-of levels of scalability, flexibility, and cost-effectiveness. In order to maximize resource utilizatio and guarantee peak performance in cloud settings, dynamic resource allocation is essential. In order to provide a thorough grasp of the most recent developments in this subject, this survey paper offers an in-depth review of dynamic resource allocation methods in cloud computing. The survey includes a wide range of dynamic resource allocation techniques, including as cost-optimization methods, resource provisioning and scheduling techniques, and load-balancing algorithms. Each method is examined in terms of its advantages, drawbacks, and applicability to particular cloud deployment scenarios. The research also investigates evaluation approaches and performance indicators for evaluating the efficacy of dynamic resource allocation systems. It emphasizes the need for continued research and innovation to address the evolving demands of cloud computing environments.
Combined Grade Concrete Mix Design
Authors: Kamble Rutika
Published: June 2023

Abstract: The process of selecting suitable ingredients of concrete and determining their relative amounts with an objective of producing a concrete of required strength, durability, and workability as economically as possible is termed as concrete mix design. Here we are doing concrete mix design of M240, M40PT, M50 grade by adding various types of admixtures and get more strength as well as it’s become less time consuming mix design as far as time is concern. Concrete mix design is a wellestablished practice around the world. All developed countries, as well as many developing countries, have standardized their concrete mix design methods. These methods are mostly based on empirical relations, charts, graphs, and tables developed as outcomes of extensive experiments and investigations of locally available materials. All of those standards and methods follow the same basic trial and error principles. The process of selecting suitable ingredients of concrete and determining their relative amount with the objective of producing a concrete of required strength durability and workability as economically as possible is termed the mix design. Some of the prevalent concrete mix design methods are: a) IS method b) ACI Mix Design Method, c) British Mix Design Method The concrete mix produced under quality control keeping in view the strength, durability, and workability is called the design Mix. Others factors like compaction equipment's available, curing method adopted, type of cement, quality of fine and coarse aggregate etc. have to be kept in mind before arriving at the mix proportion. The design mix or controlled mix is being used more and more in variety of important structures, because of better strength, reduced variability, leaner mixed with consequent economy, as well as greater assurance of the resultant quality.
Flexural Behaviour of SCC Beams Incorporating Industrial Wastes
Authors: N Sharankumar
Published: June 2023

Abstract: Self-Compacting Concrete (SCC) is a concrete form developed in Japan. Because of its novelty, this form of concrete differs from traditional concrete. Compaction is required for conventional concrete, but not for SCC which is utilized in substantially reinforced constructions where it is challenging to compact concrete. Industrial wastes such as Fly Ash (FA) and Cement Kiln Dust (CKD) [which contaminate the environment] are used as partial replacements for cement, and, Granite Powder (GP) and Eco Sand (EC) are used as partial replacements for M-sand. The optimum mix proportions of casted beams obtained by Taguchi method are SCC1 (FA30%), SCC2 (FA25%+CKD5%), SCC3 (FA30%+GP20%), SCC4 (FA25%+CKD5%+GP20%), SCC5 (FA30%+EC10%), and SCC6 (FA25%+CKD5%+EC10%). For each composition, the flexural behavior of SCC beams is experimentally investigated. Experimental work is verified by FEM analysis using the ABAQUS software. When the outcomes from the experimental and numerical analysis are compared, it is evident that SCC6 outperformed other mixes in terms of flexure
Fingerprint Based Attendance System Using Atmega328P
Authors: Jamadade Sujit , Mule Siddheshwar , Lambe Somnath
Published: June 2023

Abstract: In most schools and institutions, pupils' attendance is formally noted in duplicate on a piece of paper.They mark phoney student attendance using prohibited methods. The accuracy of the attendance is improved by fingerprint-based systems. The marking of attendance typically takes five minutes. The participation indicated following student identity. A fingerprintbased identification method is utilised to identify students. It is thought to be the quickest technique for biometric identification. Additionally, attendance rates are computed to create a distinct defaulter list, which is then periodically sent to students. The gadget differs from the others in that it is brief
Vision and Voice Based Hand Gesture Recognition
Authors: Raheem S. Abdul , Sai A. Shiva , Keerthana B. , Amulya Asst. Prof. Mrs. A.
Published: June 2023

Abstract: The development of sign language over time has been astounding. It's unfortunate that this language has some unpleasant side effects. Not everyone can understand spoken sign language when using sign language among a mute or deaf person. For deaf-dumb people, hand gestures and sign language are important forms of communication. Communication is difficult without an interpreter, hence it is necessary to translate sign language so that it is understandable to the general public. The goal is to increase the participation of the deaf and the mute in communication. In order to incorporate colour, depth, and trajectory information to increase performance, the CNN is fed numerous channels of video streams that include body joint locations in addition to depth cues and colour information. We demonstrate how the proposed model outperforms conventional approaches based on hand-crafted features by testing it on a real dataset gathered using Microsoft Kinect.
Trends in Research on Language of Infants
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Hwewon , Kwon Eunjin
Published: June 2023

Objectives The purpose of this study was to examine research trends related to infant language published in Korea from 2007 to 2020, in order to suggest directions and implications for research in the field of infant language. Methods A total of 165 studies related to infant language were analyzed for trends by research period, research subject, research method, and research topic. Results As a result of this study, by research period, it was published at a similar level from 2007 to 2011, then increased from 2012 to 2015, and then gradually decreased. By research subject, studies targeting infants were the most common, followed by mixed studies involving infants and adults, literature studies, and studies involving adults. By research method, quantitative research was the most common, followed by qualitative research, literature research, and mixed research. By research subject, language development was the most common, followed by vocabulary development, communication, instructional media, parental environment, developmental factors, reading, program, physical environment, teaching method, and teacher environment. Conclusions Based on these results, the research direction and educational implications for the future research and development in the field of language of infants were presented.
A Study on Differences in Burnout according to the Types of Counselor Work-Life Balance
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee So-Lib , Choi Hanna
Published: June 2023

Objectives The purpose of this study is to categorize counselor’s work-life balance types according to their levels of three sub-factors of work-life balance (work-family balance, work-leisure balance, work-growth balance) and to examine the differences in psychological burnout among these types. Methods A survey was conducted on 315 counselors working in Seoul and Gyeonggi regions, and a correlation analysis was performed between work-life Balance and psychological burnout. Hierarchical cluster analysis was conducted on the three variables of sub-factors of work-life balance, and one-way ANOVA and MANOVA were performed to confirm differences in psychological burnout by type. Results A significant negative correlation between work-life balance and psychological burnout was found. Counselors’ work-life balance types were best divided into four clusters: “satisfied counselors”, “average counselors”, “overly growth-focused counselors”, and “overloaded counselors”. There were differences in the overall mean and all sub-factors of psychological burnout by type. Conclusions “Overly growth-focused counselors” showed more emotional exhaustion than “average counselors”, indicating that even if counselors are content with their work-growth balance, they may experience emotional exhaustion if their work-leisure balance is inadequate. This finding underscores the importance of effective time and energy management between work and non-work activities to prevent and recover from psychological burnout. It also suggests that counselors need to balance their lives by engaging in activities that enjoy and care for themselves as individuals, as well as striving for self-development in their non-work lives.
Analysis of awareness, satisfaction and support needs for intellectual property education (IPA) for teachers in charge of IPA
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Nuri , Park Sujin , Mun Kongju
Published: June 2023

Objectives The purpose of this study is to analyze the perception, satisfaction, and support demand of intellectual property education teachers in charge of intellectual property education, and to provide implications for the future intellectual property education teacher education. Methods In Korea, 203 (92.3%) copies were extracted through an online survey targeting teachers in charge of intellectual property education at invention education centers designated by the Korean Intellectual Property Office, specialized high schools, and education offices, etc. The trend was identified. Through group comparison, differences in response results according to teaching career, training participation, class experience, etc. were statistically verified using the t-test and one-way analysis of variance (ANOVA). Results Result As a result of analyzing the understanding of intellectual property education, about 18.37% of the teachers responded that they did not know well, and there was a significant difference in understanding according to teaching experience, training, and class experience. Awareness was high. Regarding the content to be included in intellectual property education, teachers at all school levels recognized that intellectual property protection should be dealt with most importantly, and there was a difference in perception of the part to be treated as important by school level. Teachers' satisfaction with intellectual property education was low at 2.85 points, and as a result of an analysis of current state awareness on school or education office support, 47.41% of respondents recognized that it was not sufficient. Conclusions It is necessary to organize the scope and contents of intellectual property education according to the school level, and it is necessary to establish support measures in terms of supporting learning and experience programs, utilizing assistant instructors and external human resources, and developing and distributing textbooks and tutorials.
Cooking the Course from Scratch
Authors: Petrovic-Dzerdz Maristela , Marini Anthony
Published: June 2023

Applying course design fundamentals grounded in sound pedagogy is a critical first step when creating outcome-based, student-centred learning experiences. In the described three-hour workshop, the participants worked collaboratively to design a learning activity that included recognition of prerequisite skills and learning outcomes aligned with both instructional strategies and assessment processes. On completion of the activity, each group presented to all participants who, along with facilitators, provided constructive feedback on all components of the designed activity. Workshop satisfaction feedback from seven sessions (four in-class and three online) indicates that the participants were highly satisfied and felt more confident in applying the fundamentals when designing learning activities for their courses.

Keywords: course design, learning experience, teaching, educational development.
An Open Education Journey: Connecting Student Affordability with Pedagogical Enhancement
Authors: Smith Clayton , Babich Carson , Lubrick Mark
Published: June 2023

Providing educational resources without burdening students financially is considered higher education’s moral and sensible mission (Farrow, 2016). The financial burden of one or multiple textbooks can produce a great deal of stress on students, especially if the textbooks do not fulfill students’ needs in satisfying learning objectives. We attempted to bridge this digital divide by connecting student affordability with pedagogical enhancement to increase teaching impact on students’ learning. This essay will discuss the experiential understanding of student affordability, how teaching and learning can be improved by using Open Educational Resources (OER), and the team dynamic that developed while creating an OER for an undergraduate education course.
Estrategias de enseñanza para el compromiso y su influencia en el repertorio de los profesores
Authors: Fuenmayor Moncada Jose Humberto , Villalobos De León Vanessa Paola , Duque Olayo Kevin Stiven , Marín Ruiz Johanna
Published: June 2023

Este estudio de caso trata sobre un profesor de inglés como lengua extranjera (EFL) en pre-servicio, de sexo masculino, que se enfrenta a estudiantes adultos en una Universidad Privada en Medellín, Colombia, y que dio forma a su experiencia a través de la implementación de algunas estrategias de enseñanza de compromiso para construir un ambiente de aprendizaje positivo y contribuir a su repertorio como profesional en el campo de la educación. Los datos recogidos a través de la entrevista al profesor, el formato de observación de los investigadores y los cuestionarios de los estudiantes fueron analizados utilizando códigos y matrices. Los hallazgos identificaron tres estrategias de enseñanza de compromiso que el profesor en formación aplicó conscientemente dentro del aula, evidenciando que éstas forman parte de su repertorio. Los hallazgos también revelaron que cuando el profesor en formación utiliza sus estrategias en clase: establecimiento de relaciones, control del profesor y trabajo colaborativo, éstas son reconocidas por sus alumnos. El estudio podría reforzar el papel significativo del profesor y la importancia de la autoconciencia del profesor para pensar en cómo construir constantemente su repertorio y mejorar su práctica.
Media Literacy on Prevention of Pornography Effects through Personal Social Responsibility at Gerendong Village Pandeglang-Banten
Authors: Kholisoh Nur , Ganiem Leila Mona , Mijan Rohana
Published: June 2023

The social problem that is rife today is related to the impact of pornography on social media among children and adolescents. Pornography has a very big danger, especially teenagers. Adolescent psychology is still unstable and the growth of sexual hormones in adolescents, making pornography has a danger (negative impact) is very large on adolescents. Not only drugs that contain addictions, pornography also makes viewers addicted / addicted. For teens, addicted to porn sites (cybersex) will make learning rhythm become chaotic. In general, addiction to porn sites will have a negative impact on one's character. Based on research by Bingham and Piotrowski in the Psychological Report entitled On-line Sexual Addiction, the character of people who are addicted to cybersex are: Inadequate social skills, preferring to wrestle with sexual fantasy, engrossed in communication with the characters created by him. own imagination, and unable to control themselves not to access porn sites and forget time. The results of a Child Protection Commission (KPA) survey of 4,500 teenagers revealed, 97 percent of teens had watched or accessed pornography and 93 percent kissed their lips. Like chemical addiction, pornography addicts tend to replace something important with sex or other forms of pornography. People who are addicted to pornography usually use media such as magazines, porn videos or most often is the internet. Adolescents who generally still live with parents, therefore the role of supervision from parents is needed to provide an understanding of the use of social media wisely and directed to use social media positively. Parents can only provide gadgets as an easy access for their children to explore YouTube social media, but basically they also lack understanding about the media so there is still a lack of awareness for parents to control the content that their children see and consume on social media YouTube. Therefore, the need for media literacy training among adolescents is a form of prevention of the impact of pornography on YouTube social media in Gerendong Village, Pandeglang - Banten
Event-triggered state feedback control for nonlinear fractional-order interconnected systems
Authors: Cong Dinh
Published: June 2023

A new method for the design of event-triggered stabilizing state
feedback controllers for nonlinear fractional-order interconnected
systems is proposed in this paper. A new condition for the existence of
state feedback controllers ensuring the closed-loop system is
asymptotically stable is established based on fundamental mathematical
transformations and linear matrix inequalities. A numerical example with
simulation results is provided to demonstrate the effectiveness of the
proposed design method.
Distinct impacts of food restriction and warming on life history traits affect population fitness in vertebrate ectotherms
Authors: Bazin Simon , Hemmer-Brepson Claire , Logez Maxime , Sentis Arnaud , Daufresne Martin
Published: June 2023

Observed body size shifts in ectotherms are mostly attributed to the
temperature size rule (TSR) stating that warming speeds up initial
growth rate but leads to smaller size when food availability does not
limit growth. However, climate warming can decrease food availability
and we have limited information on how temperature and food jointly
influence life history traits and population fitness. We investigated
under laboratory conditions the independent and interactive effects of
temperature (20 °C and 30 °C) and food availability (restricted or ad
libitum) on the growth, fecundity and survival of the medaka fish
Oryzias latipes. We next used our empirical estimates of vital rates as
input parameters of an Integral Projection model (IPM) to predict how
modifications in vital rates translate into population demographic
parameters. Warming leads to a higher initial growth rate and lower size
leading to crossed growth curves between the two temperatures.
Food-restricted fish were smaller than ad libitum fed fish throughout
the experiment, leading to nested growth curves. Fish reared at 30 °C
matured younger, had smaller size at maturity, had a higher fecundity
but had a shorter life span than fish reared at 20 °C. Food restriction
increased survival probabilities under both temperature conditions.
According to the IPM, warming reduces generation time and increases mean
fitness in comparison to the cold treatments. Food restriction increased
generation time and fitness in the cold treatment but had no effect in
the warm treatment. Our results show that temperature and food interact
on vital rates and population demographics. This is important in the
context of global warming, as resources are expected to change with
increasing temperatures.
Lameness associated with mixed pastern pathology in a Thoroughbred yearling
Authors: Vermeulen Ashley , Booth Todd
Published: June 2023

A yearling Thoroughbred filly presented to a yearling sale with right
front lameness and radiographs demonstrating a large axial palmar OCF
(osteochondral fragment) of the proximal P2 associated with the PIP
(proximal interphalangeal) joint and no evidence of secondary
osteoarthritis. A follow up lameness examination included diagnostic
anesthesia, radiography and ultrasonography. The filly was 3 out of 10
lame right forelimb. There was pain on flexion of the distal limb and a
positive distal limb flexion test. Lameness was localised to the pastern
region. Radiography confirmed the OCF and an ultrasound examination
revealed the large OCF with small hyperechoic fragments of bone evident
in the middle scutum associated with the insertion of the axial palmar
ligament of the PIP joint and SSL (straight sesamoidian ligament). More
proximally there was a core lesion to the body of the SSL. Such large
axial palmar OCF with a comprehensive lameness examination have not been
reported yet. This provides the veterinarian information to give a
balanced opinion for risk for sale and future athletic performance.
The role of bronchial challenge test in guiding therapy in preschool children with atypical recurrent respiratory symptoms
Authors: Wolfson Yonatan , Mandelberg Avigdor , Golan-Lagziel Tal , Sosnovsky Suzanne , Ater Dorit , Domany Keren Armoni
Published: June 2023

Objective: This retrospective observational cohort study aimed
to assess the real-life application of bronchial challenge test (BCT) in
the management of preschool children presenting with atypical recurrent
respiratory symptoms (ARRS). Methods: We included children,
aged 0.5-6 years referred to a pediatric-pulmonology clinic, who
underwent BCT using methacholine or adenosine between 2012-2018 due to
ARRS including uncertain severity of airway hyperactivity. BCT was
considered positive based on spirometry results and/or wheezing,
desaturation, and tachypnea reactions. We collected data on
demographics, BCT results, pre-BCT treatment, post-BCT treatment change
and post-BCT symptoms control. The primary outcome measure was the
change in treatment post-BCT (step-up or step-down). Secondary outcome
included clinical improvement observed 3-6 months after BCT.
Results: A total of 228 children (55% males) with a mean age
of 4.2±0.6 years underwent BCT (52% adenosine-BCT, 48%
methacholine-BCT). Children referred for methacholine were significantly
younger compared to adenosine (3.6±1.2 vs. 4.2±1.2 years,
P<0.01). Methacholine and adenosine BCTs were positive in 95%
and 61%, respectively. Overall, changes in management were observed in
122(53.5%) children following BCT, with 83(36.4%) being stepped up and
37(17%) being stepped down. Significantly more children in the
methacholine group were stepped up compared to the adenosine (46% vs
28%, p=0.004). During the follow-up assessment, we observed a clinical
improvement in 119/162 (73.4%) of the children. Conclusion:
This study demonstrates the importance of BCT in the management of
preschool children presenting to pediatric pulmonary-units with ARRS.
The change in treatment and subsequent clinical improvement observed,
highlight the added-value of BCT in this populations.
Hyperbaric oxygen therapy for carbon monoxide poisoning in an adolescent with Pneumomediastinum after COVID-19 pneumonia : a case report
Authors: Zhou Hang , Haiming Wang , Yiying Liu , Yanru Chen , Haowei Zhang , Xiangyang Wei
Published: June 2023

Little is known about the complications of COVID-19. What happens when a
patient with carbon monoxide poisoning has complications from COVID-19
pneumonia (a disease that has emerged since 2019 and quickly caused a
pandemic around the world)? We report a case of carbon monoxide
poisoning with COVID-19 pneumonia resulting in secondary
pneumomediastinum. The patient underwent systemic hyperbaric oxygen
therapy for two weeks and most of his symptoms improved. This case
illustrates the success of hyperbaric oxygen in the simultaneous
treatment of COVID-19 pneumonia, pneumomediastinum, and carbon monoxide
poisoning.
The Changing Virology and Trends in Resource Utilization for Bronchiolitis since COVID-19
Authors: Orr Mary , Burks Allison , King William
Published: June 2023

Background: Bronchiolitis is a viral respiratory illness most commonly
caused by respiratory syncytial virus (RSV). COVID-19 disrupted typical
patterns of viral transmission. Our study aimed to compare low value
care for bronchiolitis in a tertiary emergency department (ED) in the
United States over the previous five years. Methods: This was a
descriptive cohort study through a retrospective chart review from
2017-2022 analyzing ED visits for bronchiolitis including disposition,
disease severity, chest radiographs, albuterol, and high flow nasal
cannula. A year was a 12 month period from March to February. Results:
In the three years prior to the pandemic, there were over 2000 ED visits
for bronchiolitis per year (3.1% of all ED visits), which decreased to
450 visits for bronchiolitis (1% of all visits) in 2020. Human
rhino/enterovirus was the most common virus detected (92%). Admission
rates, albuterol use, high flow nasal cannula use, and chest radiographs
were all higher during the first year of the pandemic. The summer of
2021 had the highest visits across the 5 study years (2743, 4.0% of all
visits) with a return to previous rates of resource utilization.
Conclusions: During the early pandemic, measures to halt the spread of
COVID-19 also altered the transmission of RSV and emergency visits for
bronchiolitis. There was an increase in lower value care while the
volume was low and rhinovirus was the dominant virus detected. As
restrictions lifted in 2021, there was a large resurgence of RSV in the
atypical summer months with a return of previous rates of resource
utilization.