bluuebunny/crossref_metadata_2025 huggingface dataset:
Robot Grasping in Random Scenarios Based on hybrid optimization algorithm (MR-GPD)
Authors: Zhnag Songsong , huang Haisong , Huang Dong , Wei Jianan
Published: April 2022

Robot grasping technology is favored by scientific researchers because of its importance in the field of robotics and its prospects. The main challenge of robotic grasping is to design an effective grasping detection algorithm for accurate grasping of the robot. Recently, various robotic grasping techniques have been proposed to improve the grasping performance of the robot. However, for random objects in an unstructured environment, even if accurate target classification is performed, multiple targets may overlap, which leads to a decline in the grasping performance of many robot grasping methods and cannot meet the accuracy requirements. To solve this problem, we propose an innovative grasping detection algorithm, which we call MR-GPD. MR-GPD is based on the robot grasping gesture detection algorithm (GPD), embeds the Mask-RCNN deep learning model to classify and segment the grasped target, then combine the results of target segmentation to construct a grasping candidate screening mechanism to evaluate and filter the outputted grasping candidates, and retain the best grasping candidate plan in the planned grasping task. To meet the requirements of the robot's actual grasping task, an improved Mask-RCNN neural network model is proposed, the speed and accuracy of target segmentation in the actual grasping process of the robot are improved, and the accuracy of the model reaches 97.5%. In this article, we conducted experimental evaluations through experimental tests and Baxter robots. The experimental results show that the method has a good grasp effect on randomly placed objects in unstructured environment, and the average success rate is about 91.2%, it reveals the feasibility of our proposed MR-GPD method, which is expected to provide important information for robot grasping in unstructured environment.
Centrosomal Protein 55 increases chromosomal instability in ovarian cancer cells by controlling microtubule dynamics
Authors: Muhs Stefanie , Joosse Simon , Paraschiakos Themistoklis , Schaefer Paula , Windhorst Sabine
Published: April 2022

Background: Centrosomal Protein 55 (CEP55) exhibits different oncogenic activities; it regulates the PI3K-Akt-pathway, cellular abscission and chromosomal instability (CIN) in different types of cancer cells. While the mechanism of CEP55-controlled PI3K-Akt signaling and cellular abscission are well-understood, its role in CIN has not been elucidated yet. Thus, the focus of this study was to address this issue.Methods: PI3K-Akt signaling was analyzed by Western blotting and cellular abscission by microtubule (MT)-life cell imaging. CIN was investigated by analyzing chromosomal alignment as well as chromosome and micronuclei number. In addition, next generation sequencing was performed. CEP55 was down- and up-regulated by lentiviral approaches and recombinantly expressed in bacteria. MT-dynamics were analyzed by turbidity and pull down assays as well as by fluorescence microscopy. Results: Depletion of CEP55 in ovarian cancer cells decreased the CIN rate, increased spindle MT-dynamics and decreased spindle MT-stability. In addition, recombinant CEP55 accelerated MT-polymerization and attenuated cold-induced MT-depolymerization. To analyze a potential relationship between CEP55 controlled CIN and its impact on MT-dynamics, the CEP55 MT-binding peptides were identified and a mutant with deficient MT-binding activity re-expressed in CEP55 depleted cells. This mutant did not restore decreased CIN in CEP55 depleted cells.Conclusion: Our data, showing that re-expression of a CEP55 mutant with deficient MT-binding activity in CEP55-depleted cells did not restore the high CIN rate of control cells, indicate that CEP55 controls CIN by binding to MTs. This knowledge now provides the possibility to selectively interfere with CEP55 controlled CIN in cancer cells.
Preoperative aminotransferase to albumin ratio correlates with tumor characteristics and predicts outcome of hepatocellular carcinoma patients after curative hepatectomy: A multicenter study
Authors: Peng Wei , Shen Junyi , Dai Junlong , Leng Shusheng , Xie Fei , Zhang Yu , Ran Shun , Sun Xin , Wen Tianfu
Published: April 2022

Aims: This study aimed to evaluate the clinical significance of the preoperative aminotransferase to albumin ratio (AAR) in patients with hepatocellular carcinoma (HCC) after hepatectomy.Methods: From five hospitals, a total of 991 patients with HCC admitted between December 2014 and December 2019 were included as the primary cohort and 883 patients with HCC admitted between December 2010 and December 2014 were included as the validation cohort. The X-tile software was conducted to identify the optimal cut-off value of AAR.Results: In the primary cohort, the optimal cut-off value of the AAR was defined as 0.7 and 1.6, respectively. Compared to patients with AAR 0.7-1.6, those with AAR >1.6 showed significantly worse overall survival (OS) and RFS, whereas those with AAR <0.7 showed significantly better OS and RFS (all p<0.001). Pathologically, patients with AAR >1.6 had more aggressive tumour characteristics, such as larger tumour size, higher incidence of microvascular invasion, and severe histologic activity, and higher AFP level than patients with AAR <0.7. Consistently, the abovementioned clinical significance of AAR was confirmed in the validation cohort. Conclusions: A high AAR was significantly correlated with advanced tumours and severe hepatic inflammation, and a worse prognosis of HCC.
Fitness consequences of chronic exposure to different light pollution wavelengths in nocturnal and diurnal rodents
Authors: Vardi-Naim Hagar , Benjamin Ava , Sagiv Tali , Kronfeld-Schor Noga
Published: April 2022

Use of artificial at night (ALAN) exposes the world to continuously increasing levels and distribution of light pollution. Our understanding of the adverse effects of ALAN is based on observational or laboratory studies, and its effects are probably underestimated. Demonstration of direct experimental fitness consequences of ALAN is missing. We studied the effects of chronic light pollution at different wavelengths on fitness and stress hormone levels under semi-natural conditions in two closely related species: the nocturnal common spiny mouse (Acomys cahirinus) and the diurnal golden spiny mouse (Acomys russatus). Our results clearly demonstrate the adverse effects of ALAN exposure on fitness of both nocturnal and diurnal species, manifested by changes in cortisol levels and reproductive timing, reduced reproductive output and reduced survival, which differed between species and wavelengths. In A. russatus exposure to blue ALAN had the strongest effect on fitness, followed by white and yellow ALAN exposure. In A. cahirinus results are more complex and suggest it suffered from combined effect of ALAN and competition. Our research shows that light pollution presents a real threat to both nocturnal and diurnal species, affecting the species fitness directly and through its interspecific interactions. Worryingly, these effects are probably not specific to spiny mice. The clear adverse effects we documented, as well as the differences between wave lengths, contribute to our ability present science-based recommendations to decision makers regarding the use of artificial light at night. Such information and guidelines are highly important nowadays when lighting systems are being replaced to promote energy efficiency.
Scabies Outbreak Investigation and Its Risk Factors in Gumbichu District, East Shewa Zone, Central Ethiopia: Unmatched Case-Control Study
Authors: Balcha Fufa , Bizuneh Hailemichael , Hunduma Fufa
Published: April 2022

Introduction: Scabies is one of the common public health problems but neglected parasitic diseases caused by Sarcoptes scabiei var hominis. Global scabies prevalence was about a 204million cases with 0.21% of total disability-adjusted life years lost. In Ethiopia, scabies is common, especially during natural or man-made disasters. This study was aimed to investigate scabies suspected outbreak and risk factors in Gumbichu District, Central Ethiopia, 2021.Methods: A community-based unmatched case-control study among 96 participants (32 cases and 64 controls) was conducted in the Gumbichu district from July 1-20/2021. Data were collected using a structured questionnaire. Line-listed data were entered into Microsoft Excel for descriptive analyses. Multivariable logistic regression analysis was computed using SPSS version 25 to identify factors associated with scabies. The odds ratio of 95% CI and a p-value less than 0.05 were used to describe the strength of the association and statistical significance.Results: A total of 1231 scabies cases line listed with overall attack rate of 16/1,000 population. The mean age was 14 years, and most affected age group was 5–14 years. Frequency of shower per month [AOR (95% CI) = 6.51(1.26-33.54)], sleeping with scabies patient [AOR (95% CI) = 10.52(3.75-29.53)], contact history [AOR (95%) = 11.44(1.72-76.22)],family size ≥5 [AOR (95% CI) = 8.63(2.42-30.84)], and sharing clothes with scabies cases [AOR (95% CI) = 14.31(3.04-67.35)] were found to be determinant factors of scabies outbreak. Conclusion: Frequency of shower per month, contact history, sleeping with scabies case, family size ≥5, and sharing clothes with scabies case were associated with a high frequency of scabies. Therefore, it is recommended to raise awareness about the transmission, prevention, and control of scabies disease.
Finite element simulation of treatment with locking platefor distal fibula fractures
Authors: Li Yafeng , Yang Wei , Zhang Xi , Yu Cheng , Ji Zhengzhao , Sun Jie , Zhang Jing
Published: April 2022

In this study, an improved finite element model is applied to compare the biomechanical stability of plates with three different options in the treatment of distal fibula fractures. A CT scan of the knee to ankle segment of a volunteer was performed. A three-dimensional finite element model of the fibula was reconstructed based on the CT data. Three different loads (uni-pedal standing, torsion, and twisting) were applied, the same as in the experiments in the literature. The stresses and strains of the three options were compared under the same loads, using a 4-hole locking plate (Option A), a 5-hole locking plate (Option B), and a 6-hole locking plate (Option C) in a standard plate for lateral internal fixation. The simulation results show that all three options showed a stress masking effect. Option C had the best overall biomechanical performance and could effectively distribute the transferred weight. This is because option C has greater torsional stiffness and better biomechanical stability than options A and B, and therefore, option C is the recommended internal fixation method for distal fibula fractures. The finite element analysis method developed in this work is applicable to the stress analysis of fracture treatment options in other body parts.
A Review of Health Related Quality of Life in Pediatric Inflammatory Bowel Disease Patients
Authors: Ahmed Saad , Alam Sadia , Alsabri Mohammed
Published: April 2022

Background:Inflammatory bowel disease (IBD) is a chronic autoimmune condition that can have a wide range of symptoms and a taxing clinical course for pediatric patients. Although clinical symptoms like hematochezia, diarrhea, and abdominal pain are commonly addressed, health related quality of life (HRQOL) is often overlooked in patients with IBD and pediatric patients with chronic disease in general.Methods:We searched through peer-reviewed primary literature related to IBD and health related quality of life, and selected 11 articles from the PubMed database to be reviewed.Results: We found patients with IBD reported worse overall HRQOL than their healthy counterparts, but greater or comparable HRQOL relative to other sick pediatric patients, including those with gastroesophageal reflux disease and chronic constipation. Some factors associated with a reduced HRQOL include disease activity, age, fatigue, gender, psychological variables, and associated symptoms.Conclusion: Examining HRQOL can improve symptoms for these patients and chart better outcomes. Thus, HRQOL should be considered by practitioners when caring for pediatric IBD patients in a clinical setting. Further, more studies, particularly prospective cohort studies and those with large and diverse samples, should be conducted to examine HRQOL in pediatric patients with chronic disease. Findings from these studies can help elucidate clinical management and early psychosocial interventions in children to reduce disease burden.
Multi-layer silicon nanoparticle solar cells: Conceptual design and performance analysis
Authors: Mirnaziry Sayyed Reza , Shameli Mohammad Ali , Yousefi Leila
Published: April 2022

We investigate the concept of nanoparticle-based solar cells composed of a silicon nanoparticle stack acting as efficient light trapping absorbers to achieve novel inorganic configurations for ultrathin photovoltaics. We study the potential of using these inherently nanotextured structures in enhancing the light absorption. For this, a detailed optical analysis is performed to demonstrate the dependency of the typical structure to physical parameters including the number of particle layers, lattice structure and angle of incidence; these behavior are then compared with conventional silicon solar cells. We propose various configurations to apply these sub-micron particles as a p-n junction solar cell. We also compute the electrical performance of selected configurations. In doing so, key issues including the effect of contact points between nanoparticles and impact of loss are addressed. In the end, we show how SiO2 nanoparticles on top of the cell structure can enhance the photocurrent. The appropriate range of SiO2 particle size is also obtained for the typical cell structures.
Estimation of Runoff Using NRCS-CN Method: A Study from South India
Authors: Mohanan Sreelakshmy , Mohanan Dhanusree , Gogoi Dipjyoti , V Thangamani
Published: April 2022

The water resource on earth surface is circulated and attains different forms; of which runoff is a major component. The runoff in any area depends on the amount of precipitation, terrain, soil type and characteristic, slope, land use activity in that region and many other location specific factors. There are several methodologies adopted world wide to estimate the runoff; one important and widely used techniques is the NRCS-CN method. This method uses precipitation, soil group and land use as the major input factors. The present study is carried out in a watershed, named the Vannathangarai watershed, a part of Noyyal river basin, which is a tributary of River Cauvery, a major river draining through southern India. The study reveals that runoff is positively correlated with precipitation and is very high in areas with slope
Canonical General Relativity and Emergent Geometry
Authors: Tee Philip
Published: April 2022

Ising models of emergent geometry are well known to possess ground states with many of the desired features of a low dimensional, Ricci flat vacuum. Further, excitations of these ground states can be shown to replicate the quantum dynamics of a free particle in the continuum limit. It would be a significant next step in the development of emergent Ising models to link them to an underlying physical theory that has General Relativity as its continuum limit. In this work we investigate how the canonical formulation of General Relativity can be used to construct such a discrete Hamiltonian using recent results in discrete differential geometry. We are able to demonstrate that the Ising models of emergent geometry are closely related to the model we propose, which we term the Canonical Ising Model, and may be interpreted as an approximation of discretized canonical general relativity.
Automatic Landmark Detection of Human Back Surface from Depth Images via Deep Learning
Authors: Delgarmi Masumeh , Heravi Hamed , Jounghani Ali Rahimpour , Darabi Mobin , Ebrahimi Afshin , Shamsi Mousa
Published: April 2022

Studying human postural structure is one of the challenging issues among scholars and physicians. The spine is known as the central axis of the body, and due to various genetic and environmental reasons, it could suffer from deformities leading to physical dysfunction and correspondingly affecting people's quality of life. Radiography is the most common method for detecting these deformities; however, it frequently exposes the patient to X-rays and ionization and consequently increases cancer risk in patients particularly children and pregnant women.The purpose of this research is to provide an entirely safe and non-invasive method to examine the spiral structure and its deformities. Hence, it is attempted to find the exact location of anatomical landmarks on the human back surface, which provides useful and functional information about the status of the human postural structure to the physician. In this study, using Microsoft Kinect sensor, the depth images from the human back surface of 105 people were recorded and, our proposed approach – a deep convolution neural network- was used as a model to estimate the locations of anatomical landmarks. In network architecture, two learning processes, including landmark position and affinity between the two associated landmarks, are successively performed in two separate branches. This is a bottom-up approach; thus, the runtime complexity is considerably reduced, and then the resulting anatomical points are evaluated concerning manual landmarks marked by the operator as the benchmark. Our results showed 86.9% of PDJ and 80% of PCK that demonstrate more effectiveness compared to other methods.
Voluntary exercise attenuates mice anxiety after traumatic brain injury via inhibiting NLRP3 inflammasome activation
Authors: Hu Xiaoxuan , Ou Yuhang , Li Jiashuo , Sun Meiqi , Ge Qian , Pan Yongqi , Cai Zhenlu , Tan Ruolan , Wang Wenyu , An Jing , Lu Haixia , Wu Gang
Published: April 2022

Background: Psychological disorders, particularly the anxiety after traumatic brain injury (TBI) have received great attention both in clinical practice and experimental investigation. New therapeutic strategies are urgently required nowadays to improve mental condition of TBI patients. Neuroinflammation is the typical adaptive response that played important roles in psychiatric illness after brain tissue damage. Therefore, the immune-targeted therapies has aroused attention. Voluntary exercise has been considered as the most essential rehabilitative intervention following TBI. However, there were some experiments showed opposite effects, which varies with different time windows. Whether and when the voluntary exercise should be taken after TBI remain to be defined. The aim of the current study was to elucidate whether in-time voluntary exercise could improve the neurological recovery and reduce the anxiety of TBI mice by inhibiting the neuroinflammation via attenuating the activation of NLRP3 inflammasome.Methods: Kunming mice (8 weeks) were subjected to TBI and randomly divided into 4 groups One week voluntary wheel running (VWR) was applied to TBI mice soon after trauma - at 2nd day after injury. The neurofunction of TBI mice was detected by neurological severity score (NSS) and beam walking assay. Anxiety behavior was evaluated by open-field (OF) test and elevated plus maze (EPM) test. The cellular inflammatory signal, including IL-12, IFN-γ, CCL2, IL-10 and TGF-β, as well as the activation of microglia and NLRP3 inflammasome in the perilesional cortex were investigated.Results: After one week VWR, neurological function recovery was enhanced while the anxiety behavior of TBI mice was significantly eased. Accompanied with this, anti-inflammatory signaling, IL-10 in particular, greatly elevated. NLRP3 expression, caspase-1 activation and pro-inflammatory cytokines IL-1β/ IL-18 secretion were significantly inhibited. All these alterations were consistent with reduced microglia activation in the perilesional site and positively correlated with the weaken of anxiety behavior.Conclusion: In-time VWR could be a high potential therapeutic strategy for neuropsychiatric disorders following TBI by targeting neuroinflammation.
Two-part intertrochanteric femur fractures with bisection of the lesser trochanter: an irreducible fracture pattern
Authors: Hu Sun-jun , Chang Shi-Min , Du Shou-chao , Zhang Li-zhi , Xiong Wen-feng
Published: April 2022

Objective To introduce the clinical features of and surgical techniques for a rare type of irreducible pertrochanteric femur fracture pattern with bisection of the lesser trochanter. Methods From Jan 2017 to Dec 2019, 357 patients with per/intertrochanteric femur fractures underwent surgery by closed reduction and internal fixation, of whom 12 patients were indentified with rare preoperative imaging features, the lesser trochanter was almost equally bisected. The main fracture pathoanatomy of these cases included: The anterior fracture line passed along the intertrochanteric line to the medial lesser trochanter and bisected it into two equal parts from mid-level of the lesser trochanteric protrusion. The proximal part of the lesser trochanter connected to the head-neck fragment and attached by the psoas major tendon, while the distal part of the lesser trochanter connected to the femoral shaft and attached by the tendon of the iliac muscle.These fractures were irreducible by a closed maneuver and were reduced with limited assistance by some devices, and short intramedullary nails were used for fixation of these fractures. The characteristics of these fracture pathoanatomy, causes of irreducibility, intraoperative techniques and clinical outcomes were summarized. Function was evaluated clinically and radiographically after a minimum of 12 months of follow-up. Results All patients were followed up for an average of 14.2 ± 2.1 months. Clinical fracture union occurred at an average of 10.8 ± 1.5 weeks, while radiographic union occurred at an average of 12.7±1.2 weeks. No cut out of the helical blade was visible on radiographs. The average Parker-Palmer score was 6.9±1.3 (range, 5–9) at the last follow up, including 8 cases rated as excellent, 2 as good and 2 as fair. Conclusion Two-part pertrochanteric femur fractures with bisection of the lesser trochanter have an irreducible fracture pattern with cortical locking and soft tissue incarceration. Soft tissue release and short cephalomedullary nail fixation for this fracture pattern provide stable fixation and allow early exercise. This treatment appears to have excellent outcomes in the short and medium terms.
Bergenin exerts antitumor effects by promoting survivin degradation
Authors: Li Xiaoying , Gan Yu , Han Shuangze , Liao Jinzhuang , Zhou Li , Li Wei
Published: April 2022

Survivin is overexpressed in multiple human malignancies and correlated with poor prognosis. In this study, we found that survivin is highly expressed in non-small cell lung cancer (NSCLC) tissues, and depletion of survivin inhibits tumorigenesis of NSCLC cells. Moreover, our results showed that bergenin, a natural product, exhibits antitumor activity against NSCLC cells. Bergenin suppresses cell viability and colony formation in A549, H1299 and H460 cells, and reduces the protein level of survivin dose-dependently. The mechanism study revealed that bergenin inhibits the phosphorylation of survivin by regulating Akt/Wee1/CDK1 signaling pathway, thereby enhancing the interaction between survivin and E3 ligase Fbxl7. In addition, bergenin enhances the expression of cleaved-PARP and -caspase 3, which promotes apoptosis of NSCLC cells. The in vivo study showed that the tumor volume, weight, and the expression of Ki67 and survivin were decreased obviously in bergenin treated group. Overall, our data indicate that bergenin has a significant antitumor activity and is a promising agent with therapeutic potential for NSCLC.
Supportive care interventions for cancer patients in low- and middle-income countries (LMICs): a scoping review
Authors: Cabanes Ana , Taylor Carolyn , Malburg Carly , Le Phuong Thao D.
Published: April 2022

PurposeIn high-income countries (HICs), supportive care is often implemented to assist cancer patients as they seek treatment and beyond. However, in low-and middle-income countries (LMICs), where more than 70% of all cancer-related deaths occur [1], the provision of supportive care has not been assessed. The purpose of this scoping review is to assess the type of supportive care interventions for cancer patients that are being implemented into practice across the cancer care continuum in LMICs.MethodsWe examined published articles reporting on supportive care interventions in LMICs. Following PRISMA guidelines, we performed a systematic search of PubMed, ERIC, CINAHL, and PsychInfo. We limited the scope to original research studies focused on LMICs, studies that implemented any type of supportive care intervention for adult cancer patients, from diagnosis, treatment, and through survivorship.ResultsThirty-five studies met the criteria for inclusion in the scoping review. The majority were randomized clinical trials (RCT) or used a quasi-experimental design. The highest number of studies (n=23) were implemented in the WHO Eastern-Mediterranean region, followed by South-East Asia (n=6), Africa (n=4) and Western-Pacific Regions (n=2). Most studies focused on women’s cancers and included interventions for psychosocial support, symptom management, health literacy/education, and patient navigation.ConclusionsAlthough only a small number of interventions are being implemented in these settings, our results suggest that providing different types of supportive services in less-resourced settings, even when health systems are fragmented and fragile, can improve mental health, physical health, and the quality of life (QoL) of cancer patients.
Error related fNIRS-EEG microstate analysis during a complex surgical motor task
Authors: Walia Pushpinder , Fu Yaoyu , Norfleet Jack , Schwaitzberg Steven D. , Intes Xavier , De Suvranu , Cavuoto Lora , Dutta Anirban
Published: April 2022

Fundamentals of Laparoscopic Surgery (FLS) is a standard education and training module with a set of basic surgical skills. During surgical skill acquisition, novices need to learn from errors due to perturbations in their performance which is one of the basic principles of motor skill acquisition. This study on thirteen healthy novice medical students and nine expert surgeons aimed to capture the brain state during error epochs using multimodal brain imaging by combining functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG). We performed error-related microstate analysis in the latent space that was found using regularized temporally embedded Canonical Correlation Analysis from fNIRS-EEG recordings during the performance of FLS "suturing and intracorporeal knot-tying" task – the most difficult among the five psychomotor FLS tasks. We found from two-way analysis of variance (ANOVA) with factors, skill level (expert, novice), and microstate type (1-6) that the proportion of the total time spent in microstates in the error epochs was significantly affected by the skill level (p<0.01), microstate type (p<0.01), and the interaction between the skill level and the microstate type (p<0.01). Therefore, our study highlighted the relevance of portable brain imaging to capture error behavior when comparing the skill level during a complex surgical task.
Real-Time Course: Reconstruction of cellular diversity and lineage trajectory based on somatic mutational patterns detected from low-pass single-cell transcriptome data
Authors: Oota Satoshi , Abe Kuniya , Yokota Hideo , Ikeo Kazuho
Published: April 2022

Single-cell RNA-seq (scRNA-seq) analysis can describe the states of individual cells but cannot clarify direct relationships between cells. Therefore, we developed a method to trace the progenitor cells of cell differentiation pathways through the cell lineage using somatic mutations detected in low-pass scRNA sequences. Using two human placental tissue datasets, we detected 2,172 and 627 somatic mutation candidates. We used only somatic mutation data to classify placental cells and construct a phylogenetic tree; the results were consistent with those of cell classification by expression profiling and estimation of the differentiation process by pseudotime course analysis. Somatic-mutation-based analysis can determine the temporal order of individual cells in the cell lineage, which is not possible with pseudotime analysis. Therefore, somatic mutation signatures in scRNA-seq data are informative for constructing cell lineages, and in combination with expression data obtained simultaneously, they are extremely useful for delineating the processes of human development and pathogenesis.
METHODOLOGY OF QUANTITATIVE ASSESSMENT OF THE ECONOMIC POTENTIAL OF INVESTMENT POLICY ON THE BASIS OF A MACHINE-BUILDING ENTERPRISE
Authors:   Irkutsk National Research Technical University, Irkutsk, Wenfu Zhao , Beregova G. ,   Irkutsk National Research Technical University, Irkutsk
Published: April 2022

This article proves that investment policy plays an important role in achieving the vision and mission of the organization, and in order for it to be effective, it must be coordinated with the investment strategy, i.e. a high-level strategic plan to achieve your investment goals. It is revealed that the revision of the policy makes it possible to identify the main problems in the company that affect the investment process as a whole, as well as to identify the compliance of the skill sets and capabilities of the participants involved in the implementation of the policy and the general direction in which improvement work can be carried out. The article provides an overview of the processes that need to be taken into account in the process of reviewing and developing investment policy. This assumes that the organization has already revised its investment strategy and all significant long-term factors within it. The stages of investment policy formation are structured, reflected in the review of existing investment strategies; coordination of stakeholders; review of relevant legislation; familiarization of management with internal and external factors; expert evaluation. The article presents a methodology based on the mathematical method of constructing investment strategies. The construction of an economic and mathematical model has helped to establish a link between investment strategies within the framework of the investment policy implementation and the economic effect obtained from them
TRANSPORT COMMUNICATIONS AS A TOOL FOR THE IMPLEMENTATION OF MONGOLIAJS DOMESTIC AND FOREIGN POLICY
Authors:   Transbaikal State University, Chita, Beydina T. , Litovchenko A. ,   Transbaikal State University, Chita, Novikova A. ,   Transbaikal State University, Chita
Published: April 2022

The article examines Mongolia - a landlocked country located between its neighbors, the Russian Federation and the PRC. Due to the lack of direct access to the sea, limited geographical opportunities, as well as due to certain historical aspects, Mongolia faces challenges that are directly related to its foreign and domestic policy initiatives. These include the need to diversify natural resources to accelerate the country's socio-economic development and increase its influence on the world stage. During its socialist existence, Mongolia was oriented towards the Union of Soviet Socialist Republics. After the collapse of the socialist bloc, Mongolia followed the path of democratic transformations, defining integration with Northeast Asia as a foreign policy priority. The geographical location of Mongolia, the remote distance from the seas and the location between two large neighbors make its external transport links very important from the point of view of international trade for the country. In this regard, the development of transport infrastructure will help economic diversification and sustainable development of Mongolia. The regional cooperation and integration are Mongolia's main goals to maximize the benefits of its geographic location. Mongolia currently uses Chinese ports for almost all its imports and exports and has a small volume of freight traffic through Russian Pacific ports to ship goods to and from North America. In this regard, to reduce economic dependence on China, the Mongolian side interested in expanding cooperation with Russia in the development of transport communications to create a competitive pricing of exported products. At the same time, the implementation of a successful foreign policy is hampered by the country's internal political processes associated with an unfair distribution of power, government instability, high level of corruption, and the absence of a unified and consistent resource policy■丨n addition, as noted by Mongolian experts, to solve the problem of diversifying the economy it is necessary to improve the legal environment for investment, and to increase the transparency of the work of foreign mining companies
DEVELOPMENT AND COMPARISON OF THE REGRESSION MODELS OF GOLD-BEARING MATERIAL SEPARATION USING A CENTRIFUGAL JIGGING MACHINE
Authors:   JSC «Irgiredmet»， Irkutsk, Luchko М. , Fedotov Р. ,   Irkutsk National Research Technical University，Irkutsk, Lukyanov N. ,   Irkutsk National Research Technical University，Irkutsk
Published: April 2022

Decreasing ore grades is a common challenge for every gold mining country in the world. Deposits of low-grade and complex ores are increasingly brought into production. These ores are typically treated by hydrometallurgical methods, for example, heap leaching. Meanwhile, the use of cyanide and its alternatives poses a risk for the environment. Thus, the development of gravity methods including jigging in a centrifugal-field is becoming an attractive option of low-grade and complex ore processing. Two mathematical models have been developed using the regression method to predict grade and recovery characteristics of the products of a centrifugal jigging machine (CJM) with variable process parameters including jig chamber rotational speed, pulsation frequency and vibration amplitude of a movable cone, underscreen-water flow rate. The models are based on the results of the field trials of a pilot centrifugal jigging machine designed by JSC Irgiredmet at existing gold-processing plants. Mathematical modelling provided a means of the process parameters ranking according to their impact on the separation process. A model has been identified that ensures a more accurate prediction of the separation process variables (metal recovery in concentrate) when the CJM's adjustable parameters are changed. The object of the study is the centrifugal jigging method of gold-bearing ore separation. The scope of the study is mathematical modelling of gold-bearing ore separation using CJM. The objective of the study is the determination and ranking of the CJM's process parameters according to their impact on the separation process, identification of a model that ensures a more accurate prediction of the separation process variables. The methodology of the study involves finding the correlation between gold grade/gold recovery into the separation products and the CJM's adjustable parameters. The method of the study is regression analysis
SEPARATION OF RUSSIAN BOLSHEVIKS AND RUSSIAN EMIGRANTS IN NORTHEAST CHINA
Authors:   Heilongjiang University,   Harbin, China
Published: April 2022

During the construction of the Middle East Railway in 1897-1903, the railway administration employed almost 200,000 Russian workers, including some Bo丨sheviks. They have a丨ready conducted propaganda and revolutionary activities in Harbin and other areas of the Middle Eastern Railway. With the opening of the Middle East Railway in 1903, revolutionary thoughts and Bolsheviks in Russia also came to Northeast China. The Bolsheviks actively led the Workers’ movement, created Bolshevik organizations and founded propaganda publications in Northeast China. During this period, Marxism became widespread in Northeast China. In fact, even before the appearance of the Russian Bo丨sheviks, the ear丨y spread of Marxism in the northeast of China had a丨ready begun, but the effect of the spread was not obvious. With the deve丨opment of Bo丨shevik revo丨utionary propaganda and the spread of Marxist ideas, the number of Marxist believers among Russian workers in the Middle East has increased
MODEL OF EFFECTIVE INFORMATION SECURITY POLICY IN THE CONTEXT OF MANAGEMENT PRACTICE
Authors:   Transbaikal State University, Chita, Beydina T. , Kukharsky A. ,   Transbaikal State University, Chita, Novikova A. ,   Transbaikal State University, Chita
Published: April 2022

The article is devoted to the study of policy in the field of information security management and is relevant, since it contains an assessment of the effectiveness of the information security management model. However, our review of the information security management literature has identified four major weaknesses that reduce the usefulness of recommendation characteristics for state and municipal governments implementing information policy management practices. The aim of this article is to provide a comprehensive overview of information security policy management and to develop a model based on the generalization of practice. Our review of foreign literature shows that it is advisable to characterize an effective model of information policy management for government bodies. However, there is a number of shortcomings that reduce the usefulness and effectiveness of the information policy model for authorities in the implementation of security policy. In the literature, in our opinion: there is no holistic view of the information policy model (deficiency 1); there is no uniformity in terminology and semantics (flaw 2); different levels of detail are used when describing policy management actions (flaw 3); and it is difficult to use information policy management guidance from other practice areas such as risk management, information practice training and security awareness (Gap 4). The authors structure the article as follows. Firstly, it examines the existing lifecycles of information security policy management. Secondly, the authors explain the research methodology used to review and analyze the literature. Thirdly, the authors propose a model of management practices related to information security policy. Fourthly, the authors explain how the proposed model eliminates the identified shortcomings. Two conclusions can be drawn from the study: 1) the model of information security policy management involves the enforcement of power aimed at managing risks; 2) the model is focused on identifying 3 stages of institutionalization - the development, implementation and assessment of management activities
INVESTMENT POLICY OF THE STATE AS AN INSTRUMENT OF ECONOMIC GROWTH
Authors:   Transbaikal State University, Chita, Burov V.
Published: April 2022

The article defines the role of the state's investment policy as an instrument for the effective development of the leading sectors of the economy, the stable functioning of the basic infrastructure, achieving macroeconomic stability and stimulating economic growth. The object of the study is the investment policy of states. The subject of the study is the mechanisms of economic growth of the country. The purpose of the study is to identify and scientifically substantiate the role of investment policy in the economic growth of the country. A detailed analysis of the share of capital investments in GDP, the index of investments in fixed assets for 2017-2021 is presented, and the investment policy determining the state of developed countries and developing countries is also evaluated. The methods of correlation and regression analysis used made it possible to determine the relationship between real GDP, the share of industrial production in GDP and the index of investment in fixed assets in countries with a transforming economy. It is established that in the vast majority of countries, an increase in investments in fixed assets contributes to the acceleration of economic growth, and the level of economic growth determines the investment potential of countries. It is determined that the heterogeneity of the impact of investments on the level of economic growth in countries with transformational economies is due to their raw orientation, insufficient level of validity and predictability of the implemented investment policy of the state. It is proved that the investment policy of the state is an important tool for ensuring macroeconomic stability and stimulating economic growth in a recession. It is proposed to create conditions for the macroeconomic balance that contribute to the increase of business activity of enterprises due to the purposeful influence of state investment policy on economic processes by ensuring qualitative transformation and innovation of the national economy. The results obtained show that the level of influence of public investment in relation to the level of economic growth varies significantly depending on the level of development of financial institutions in the country and the infrastructure of the financial market
Mobile Application Characteristics and User Perspective in Smart Healthcare Service Applications
Authors: Jayanti Ni Ketut Dewi Ari , Triandini Evi , Sastrawangsa Gde , Deriani Ni Wayan
Published: April 2022

The current COVID-19 pandemic has an impact on accelerating the digital transformation of various sectors in Indonesia, one of which is the health sector. Hence, many mobile applications of smart healthcare service have been developed, which can be a solution for people to get better health services. The aim of the research is to evaluate the mobile application (SpeedId and SpeedQ) for smart healthcare service based on the user perspective and the characteristics of the mobile application. The research is an analytic observational study that contains five stages of research. There are 64 respondents in the research using a questionnaire as data collection tool. Then, through a literature review, seven variables are determined, and a research model is proposed. The evaluation of the mobile application characteristics includes the operating system and network availability as independent variables and response time, responsiveness, and interface accessibility as dependent variables. Meanwhile, evaluating user perspective consists of respondents’ gender and education as independent variables and duration and ease of use as dependent variables. From the mobile application characteristics, the results show that operating system and network availability do not significantly affect all dependent variables. From the user perspective, gender only significantly affects the duration variable. Meanwhile, education significantly impacts the duration and the ease of use.
Status of Intervocalic [kː] and [tː] in the Phonological System of the Teleut Language
Authors: Tokmashev D. M.
Published: April 2022

This article deals with the consonant phonemes /kː/~/k/ and /tː/~/t/ of the Teleut language in the intervocalic position. These sounds were contrasted as long and short ones in the previous studies. The paper offers a brief review of works on the formation and development of the Turkic consonantism and the problem of long consonants in the ancient and modern Turkic languages. The author focuses on the relevance of the short – long opposition for the Teleut stop consonants in the intervocalic position and makes an assumption that their length depends on their position and morphonology. The Turkic languages have two non-mutually exclusive types of consonant length: the qualitative length of voiceless consonants caused by aspiration and the quantitative length of the geminates caused by the extended closure. The research involved a Praat comparative analysis of sonograms of lexical stimuli that illustrated the length of [k] and [t] in intervocalic positions. The preliminary conclusion is that Teleut stops [k] and [t] are contrasted according to their voicing, while the length opposition seems to be a less significant discriminating feature. The sonogram also proved their voicing.
Representations of continuous piecewise affine functions
Authors:   St. Petersburg State University, Malozemov Vassili N. , Tamasyan Grigoriy Sh. ,   St. Petersburg State University,   Institute of Problems of Mechanical Engineering of the Russian Academy of Sciences
Published: April 2022

Continuous piecewise affine functions are widely used in computational mathematics. In one-dimensional case such functions are called broken lines. The article analyzes the analytical representations of broken lines in the forms accepted in the theory of polynomial splines as well as in the form of the difference of the maxima of two finite families of affine functions. The connection between these representation is being determined.
Stability of a vertical descent of a heavy finned body in resisting medium
Authors:   Institute of Mechanics of Lomonosov Moscow State University, Samsonov Vitaliy A. , Privalova Olga G. ,   Institute of Mechanics of Lomonosov Moscow State University, Okunev Yuriy M. ,   Institute of Mechanics of Lomonosov Moscow State University
Published: April 2022

A free descent of a finned body in resisting medium is studied. Fins are installed in such a way that there is a regime of a translational descent with a constant speed. Beforehand, a descent of a heavy body in an autorotation mode was studied. It exists when pitch angles of all fins are equal to each other. For a descent with autorotation, general properties and tendencies of motion were described depending on initial conditions and parameters. In the current paper, the descent of a body is discussed for the case when fins have equal absolute values of pitch angles, but signs of these angles alternate. Asymptotic stability of a translational descent with a constant speed is studied for such orientation of fins. Domains of stability are constructed in the plane of the following parameters: pitch angle of fins and displacement of the center of mass. Fins represented either by circle or rectangular blades are discussed. Domains of stability are compared with that for the autorotation mode descent. Trajectories of the center of mass are constructed. Varied types of such trajectories are obtained when parameters of the model correspond to the case of unstable translational descents with a constant speed.