bluuebunny/crossref_metadata_2025 huggingface dataset:
Circular RNA hsa_circ_0006848 Related to Ribosomal Protein L6 Acts as a Novel Biomarker for Early Gastric Cancer
Authors: Lu Jun , Zhang Peng-yang , Xie Jian-wei , Wang Jia-bin , Lin Jian-xian , Chen Qi-yue , Cao Long-long , Li Ping , Zheng Chao-hui , Huang Chang-ming
Published: September 2019

Objective. Circular RNAs (circRNAs) have been reported to be widely involved in pathological processes of various cancers. However, little is known about their diagnostic values in early gastric cancer (EGC). This study is aimed at exploring whether circulating circRNAs in plasma could act as biomarkers for EGC diagnosis. Materials and Methods. Mass spectrometry (MS) was performed to identify the proteins that at significantly aberrantly levels in gastric cancer (GC) tissues. The target circRNA was identified by bioinformatics analysis. A receiver operating characteristic (ROC) curve was generated to evaluate the diagnostic utility. Results. MS revealed that the ribosomal protein L6 (RPL6) expression was significantly downregulated only in EGC tissues vs. nontumorous tissues; this was validated by western blotting (n=30, p=0.0094). Bioinformatics analysis predicted that there is a hsa_circ_0006848/hsa_miR-329-5p/RPL6 axis in GC progression. The hsa_circ_0006848 expression was significantly downregulated in EGC tissues (vs. nontumorous tissues, n=30, p=0.0073) and plasma samples from EGC patients (vs. paired healthy volunteers, n=30, p=0.0089). In addition, the hsa_circ_0006848 plasma level in postoperative patients was significantly higher than that of preoperative patients (n=30, p=0.047). Furthermore, the decreased hsa_circ_0006848 expression in plasma was negatively correlated with poor differentiation (p=0.037) and tumor size (p=0.046). The area under the ROC curve (AUC) of hsa_circ_0006848 in plasma was 0.733, suggesting a good diagnostic value. The plasma hsa_circ_0006848 level combined with the carcinoembryonic antigen (CEA), carbohydrate-associated antigen 19-9 (CA19-9), and carbohydrate-associated antigen 72-4 (CA72-4) level increased the AUC to 0.825. Conclusion. Our results indicated that plasma hsa_circ_0006848 may be a novel noninvasive biomarker in EGC diagnosis.
Effects of MRgFUS Treatment on Musculoskeletal Pain: Comparison between Bone Metastasis and Chronic Knee/Lumbar Osteoarthritis
Authors: Namba Hirofumi , Kawasaki Motohiro , Izumi Masashi , Ushida Takahiro , Takemasa Ryuichi , Ikeuchi Masahiko
Published: September 2019

Local bone denervation by magnetic resonance-guided focused ultrasound (MRgFUS) is a promising tool for alleviation of pain in patients with painful bone metastasis (BM). Considering the underlying mechanism of pain alleviation, MRgFUS might be effective for various bone and joint diseases associated with local tenderness. This study was conducted to clarify the therapeutic effect of focused ultrasound in patients with various painful bone and joint diseases that are associated with local tenderness. Ten patients with BM, 11 patients with lumbar facet joint osteoarthritis (L-OA), and 19 patients with knee osteoarthritis (K-OA) were included. MRgFUS treatment was applied to the bone surface with real-time temperature monitoring at the target sites. Pain intensity was assessed using a 100 mm numerical rating scale (NRS) at various time points. Pressure pain threshold (PPT) was evaluated on the sonication area and control sites. Compared to baseline, the pain NRS scores significantly decreased in all groups 1 month after treatment, and PPT at the treated sites significantly increased in all groups 3 months after treatment. The percentage of patients who showed a ≥ 50% decrease in pain NRS scores at 1 month after treatment was 80% in BM, 64% in L-OA, and 78% in K-OA groups. PPTs were significantly higher after treatment at all evaluation time points. This study indicated that MRgFUS is effective in reducing pressure pain at the site of most severe tenderness in patients with painful bone and joint diseases. Treatment response was comparable between patients with BM, L-OA, and K-OA.
Suppression of Current Fluctuations and the Brake Torque for PMSM Shutoff in Electric Vehicles
Authors: Lu Ke , Zhu Yuan , Wu Zhihong , Xiao Mingkang
Published: September 2019

When a safety‐related fault in the motor controller is detected, the torque output of the motor cannot be effectively shut off in time and an overcurrent occurs at the moment of switching. The advantages and disadvantages of the open circuit and active short‐circuit methods are analyzed. Combining the advantages of these two operations, this paper proposes a new mixed voltage modulation method. It introduces a voltage modulation ratio that represents the duty cycle of the open circuit operation during a PWM period. This ratio is first set to a fixed value and gradually reduced to zero. The inverter is switched at a mixed operation and finally remains in the active short‐circuit mode. The current can be quickly converged by a freewheeling diode of open circuit. After switching to active circuit, the brake torque is safety. The effectiveness of this shutoff method was verified by simulations and experiments. It shows that current fluctuations are suppressed and the torque output is also within a safety range. In addition, this shutoff method does not require any additional sensor information and is simple to implement.
Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results
Authors: Walkiewicz Katarzyna , Strzelczyk Joanna , Waniczek Dariusz , Biernacki Krzysztof , Muc-Wierzgoń Małgorzata , Copija Angelika , Nowakowska-Zajdel Ewa
Published: September 2019

Colorectal cancer is one of the most common cancers in the world. Due to its still undetermined pathogenesis, we are searching for signaling pathways that are important in the development of colorectal cancer. In this article, we present results of study on the role of ADAM proteins in colorectal cancer. The study included 85 adult colorectal cancer patients (48 men, 37 women) and 25 patients in the control group (after diagnostic colonoscopy—without cancer). During hospitalization, a serum sample (3 cm3) was collected from the study and control group, anthropometric measurements were conducted and others clinical data were analyzed. In the serum ADAM10, 12, 17, and 28, protein concentrations were determined and, in the next step, examined the relationship between ADAMs concentrations and selected clinical parameters in both groups. The analysis showed that serum levels of ADAM10 and ADAM28 are significantly higher in patients with colorectal cancer and correlate with histopathological grading and with presence of distant metastases. Moreover, noticed the trend to correlate concentrations of adamalysines with higher BMI score. One of the functions of adamalysines is the activation of growth factors involved in cancer, including IGF and TNFα. The increased activity of adamalysines in patients may play a role in the pathogenesis of colorectal cancer. Our study highlights the prevalence of metabolic disorders in the group of patients with diagnosed CRC, and this cancer seems to be a further complication of obesity.
Evaluation of a 38 L Explosive Chamber for Testing Coal Dust Explosibility
Authors: Eades Robert , Perry Kyle
Published: September 2019

Coal dust explosions are the deadliest disasters facing the coal mining industry. Research has been conducted globally on this topic for decades. The first explosibility tests in the United States were performed by the Bureau of Mines using a 20 L chamber. This serves as the basis for all standardized tests used for combustible dusts. The purpose of this paper is to investigate the use of a new 38 L chamber for testing coal dust explosions. The 38 L chamber features design modifications to model the unique conditions present in an underground coal mine when compared to other industries where combustible dust hazards are present. A series of explosibility tests were conducted within the explosive chamber using a sample of Pittsburgh pulverized coal dust and a five kJ Sobbe igniter. Analysis to find the maximum pressure ratio and Kst combustible dust parameter was performed for each trial. Based upon this analysis, observations are made for each concentration regarding whether the explosibility test was under-fueled or over-fueled. Based upon this analysis, a recommendation for future explosibility testing concentrations is made.
Utilization of an Optimized Radiation Strategy in Primary Percutaneous Coronary Intervention for Patients with ST-Segment-Elevation Myocardial Infarction
Authors: Zhong Xin , Gao Wei , Huang Dong , Ge Lei , Qian Juying , Ge Junbo
Published: September 2019

Background. Recent reports about radiation risk gradually raised the safety concerns for interventional therapy. However, limited data exist on the optimized radiation strategy in primary percutaneous coronary intervention (P-PCI) for patients with ST-segment-elevation myocardial infarction (STEMI). Methods. A total of 214 STEMI patients undergoing P-PCI were retrospectively analyzed. Patients were divided into the optimized radiation strategy (ORS) group (N = 151) and normal radiation strategy (NRS) group (N = 63) according to the radiation protocol utilized. The primary endpoint was the relative dose reduction of total air kerma. The secondary endpoint was 30-day major adverse cardiac and cerebrovascular events (MACCE), as a composite of all-cause death, reinfarction, ischemia-driven target vessel revascularization, and stroke. Results. Patient groups were well matched for baseline characteristics. There were no differences in terms of age, body mass index, radial artery access, nonculprit vessel PCI, and fluoroscopy time between 2 groups. With optimized radiation strategy, a 40.9% radiation dose reduction (901.2 ± 628.7 mGy versus 1524.0 ± 866.6 mGy, p<0.001) was obtained for total air kerma. No significant differences were found for 30-day MACCE between 2 groups (2.0% versus 1.6%, adjusted hazard ratio: 0.7, 95% confidence interval: 0.1 to 8.6, p=0.772). Conclusion. With optimized radiation strategy, significant radiation dose reduction could be achieved in P-PCI for STEMI patients. It appears to be feasible and safe to carry out the optimized radiation strategy in P-PCI for STEMI patients.
Variational and Numerical Analysis for Frictional Contact Problem with Normal Compliance in Thermo-Electro-Viscoelasticity
Authors: Bouallala Mustapha , Essoufi El Hassan , Alaoui Mohamed
Published: September 2019

In this paper, we consider a mathematical model of a contact problem in thermo-electro-viscoelasticity with the normal compliance conditions and Tresca’s friction law. We present a variational formulation of the problem, and we prove the existence and uniqueness of the weak solution. We also study the numerical approach using spatially semidiscrete and fully discrete finite element schemes with Euler’s backward scheme. Finally, we derive error estimates on the approximate solutions.
Needle Licker’s Osteomyelitis Revisited: An Unusual Case of Vertebral Osteomyelitis withEikenella corrodensin a Diabetic Patient
Authors: Roth Bianca , Schimke Katrin-Elisabeth , Ruckstuhl Agnes , Külling Fabrice , Dietrich Tobias , Strahm Carol
Published: September 2019

Vertebral osteomyelitis due toEikenella corrodensis extremely rare. We report an unusual case of an infection caused byE. corrodensin a self-insulin-administering patient with diabetes. Similar to needle licker’s osteomyelitis, our case shows most likely the same pathomechanism and stresses the importance of correct insulin application.
Research on Association of the Diameter of the Internal Carotid Artery Siphon and Nonarteritic Anterior Ischaemic Optic Neuropathy
Authors: Fu Zhiyong , Li Hongyang , Wang Wei , Wang Yanling
Published: September 2019

Objective. To investigate the association of the diameter of the internal carotid artery siphon (ICAS) and nonarteritic anterior ischaemic optic neuropathy (NAION).Methods. Thirty patients clinically diagnosed with NAION (unilateral affected) who presented to Beijing Friendship Hospital from January 2017 to October 2018 were selected. The eyes suffered from NAION were enrolled as the observation group, and the fellow healthy eyes were enrolled as the control group. The following indexes were measured: diameter of the ICAS and the ophthalmic artery (OA), intima-media thickness (IMT) of the internal carotid artery (ICA), degree of stenosis of the ICA and plaque formation, and hemodynamic parameters of the ICA and the short posterior ciliary arteries (SPCAs). All the values were compared between the two groups.Results. The diameter of the ICAS in the observation group (0.30 ± 0.07 cm) significantly narrowed compared with that of the control group (0.32 ± 0.06 cm) (P<0.05), but the diameter of the OA of the two groups had no significant difference. The detection rate of carotid atherosclerosis plaque, the average blood flow velocity (Vm), and the resistance index (RI) of the ICA in the observation group (46.67%, 26.81 ± 1.78 cm/s, and 0.72 ± 0.06) had significant differences compared with those of the control group (16.67%, 28.19 ± 2.75 cm/s, and 0.70 ± 0.05) (P<0.05), but the gradings of ICA stenosis and IMT between the two groups had no significant differences. The peak systolic velocity (PSV) and the end diastolic velocity (EDV) of the SPCAs in the observation group (10.72 ± 2.88 cm/s and 3.43 ± 1.01 cm/s) were significantly lower than those of the control group (13.62 ± 3.93 cm/s and 4.59 ± 1.71 cm/s) (P<0.05), but the RI of the SPCAs of the two groups had no significant differences.Conclusion. The diameter of the ICAS has a close relationship with NAION.
Enhancing the Solubility of Curcumin Metal Complexes and Investigating Some of Their Biological Activities
Authors: Hieu Tran Quang , Thao Doan Thi Thanh
Published: September 2019

This article describes the synthesis of curcumin complexes with metal ions. Properties of these complexes such as spectra IR and UV-Vis and solubility were investigated. The optimum parameters of ultrasound to enhance the solubility was figured out as follows: the capacity of ultrasound: 750 W/g; the time of ultrasound: 7 min; the concentration of the surfactant Tween 80 : 2%. The maximum solubility (mg/ml) of complexes was as follows: Cur-Fe(III): 0.162 ± 0.01; Cur-Zn(II): 0.267 ± 0.02; and Cur-Ca(II): 0.417 ± 0.05. Antioxidant capacity (DPPH, %I) of curcumin complexes was higher than that of curcumin-free complexes. All of these curcumin complexes revealed antimicrobial activities, in which calcium complex had the best resistance against Salmonella, followed by Fe(III) complexes. Meanwhile, the zinc complex was not resistant to this bacterium. These complexes showed antibacterial activity on Staphylococcus aureus, in which Cur-Ca (II) complexes had the highest antibacterial activity. For Escherichia coli, the Cur-Zn (II) complex had no resistance, while the Cur-Ca (II) complex showed the highest antibacterial activity.
Comparison of Statistical Methods to Graphical Methods in Rainfall Trend Analysis: Case Studies from Tropical Catchments
Authors: Rathnayake Upaka
Published: September 2019

Time series analyses for climatic factors are important in climate predictions. Rainfall is being one of the most important climatic factors in today’s concern for future predictions; thus, many researchers analyze the data series for identifying potential rainfall trends. The literature shows several methods in identifying rainfall trends. However, statistical trend analysis using Mann–Kendall equation and graphical trend analysis are the two widely used and simplest tests in trend analysis. Nevertheless, there are few studies in comparing various methods in the trend analysis to suggest the simplest methods in analyzing rainfall trends. Therefore, this paper presents a comparison analysis of statistical and graphical trend analysis techniques for two tropical catchments in Sri Lanka. Results reveal that, in general, both trend analysis techniques produce comparable results in identifying rainfall trends for different time steps including annual, seasonal, and monthly rainfalls.
Identification of Aberrantly Expressed lncRNAs Involved in Orthodontic Force Using a Subpathway Strategy
Authors: Guo Xinxing , Wang Jianning , Chen Jing
Published: September 2019

Background. The aim of the study was to identify key long noncoding RNAs (lncRNA) and related subpathways in the periodontal ligament tissue following orthodontic force.Methods. We adopt a novelty subpathway strategy to identify lncRNAs competitively regulated functions and the key competitive lncRNAs in periodontal ligament disorders after undergoing orthodontic force. To begin with, patients with orthodontics in our hospital were enrolled in our research. The relationship of lncRNA-mRNA was established through shared predicted miRNA by using the hypergeometric test, Jaccard coefficient standardization, and the Pearson coefficient to determine the valid interaction relationship. After embedding screened lncRNA interactions to pathways, the significant subpathways were recognized by lenient distance and Wallenius approximation methods to calculate the false discovery rate value of each subpathway.Results. The lncRNA-mRNA intersections including 263 lncRNAs, 1,599 mRNAs, and 3,762 interacting pairs were obtained. The enriched mRNAs were further enriched into various candidate pathways such as the PI3K-Akt signaling pathway. Several subpathways were screened, including the PI3K-Akt signaling pathway, 04510_1 focal adhesion, and p53 signaling pathway, respectively. The network of pathway-lncRNA-mRNA was constructed. Several key lncRNAs includingDNAJC3-AS1,WDFY3-AS2,LINC00482, andDLEU2were screened.Conclusions.DNAJC3-AS1,WDFY3-AS2,LINC00482, andDLEU2as aberrantly expressed lncRNAs involved in orthodontic force might play crucial roles in periodontal ligament disease pathogenesis.
Pharmacokinetic Interactions between Cardiovascular Medicines and Plant Products
Authors: Costache Irina-Iuliana , Miron Anca , Hăncianu Monica , Aursulesei Viviana , Costache Alexandru Dan , Aprotosoaie Ana Clara
Published: September 2019

The growing use of plant products among patients with cardiovascular pharmacotherapy raises the concerns about their potential interactions with conventional cardiovascular medicines. Plant products can influence pharmacokinetics or/and pharmacological activity of coadministered drugs and some of these interactions may lead to unexpected clinical outcomes. Numerous studies and case reports showed various pharmacokinetic interactions that are characterized by a high degree of unpredictability. This review highlights the pharmacokinetic clinically relevant interactions between major conventional cardiovascular medicines and plant products with an emphasis on their putative mechanisms, drawbacks of herbal products use, and the perspectives for further well-designed studies.
High-Dose Neural Stem/Progenitor Cell Transplantation Increases Engraftment and Neuronal Distribution and Promotes Functional Recovery in Rats after Acutely Severe Spinal Cord Injury
Authors: Yuan Taoyang , Liu Qian , Kang Jie , Gao Hua , Gui Songbai
Published: September 2019

Severe spinal cord injury (SCI) leads to permanent, complete paraplegia and places considerable mental and economic burdens on patients, compared with mild to moderate SCI. However, the dose-related effects of the neural stem/precursor cell (NSPC) transplantation on the injury microenvironment, NSPC survival, axonal growth, neuronal distribution, the composition of neurons, oligodendrocytes, and astrocytes in the lesion area and functional recovery have not yet been quantitatively evaluated in the context of severe SCI. In our study, we acutely transplanted 2.5×104 or 1.5×105 NSPCs/μl into the site of transection SCI. We found that high-dose NSPC transplantation exerted immunomodulatory and neuroprotective effects in the acute phase of severe SCI. In addition, one week later, a remarkable positive relationship was observed between the transplantation dose and the number of surviving NSPCs in severe SCI. At 8 weeks postgrafting, subjects that received the higher cell dose exhibited abundant nerve regeneration, extensive neuronal distribution, increased proportions of neurons and oligodendrocytes, and nascent functional neural network formation in the lesion area. Notably, a significant functional recovery was also observed. Our data suggest that it is important to consider potential dose-related effects on donor cell survival, neuronal distribution, and locomotor recovery in the development of preclinical NSPC transplantation therapy for severe SCI.
Association of Chronic Kidney Disease with Preserved Ejection Fraction Heart Failure Is Independent of Baseline Cardiac Function
Authors: Mavrakanas Thomas A. , Khattak Aisha , Wang Wei , Singh Karandeep , Charytan David M.
Published: September 2019

Background/Aims: Chronic kidney disease (CKD) is common among patients with heart failure with preserved ejection fraction (HFpEF) and is associated with worse clinical outcomes. This study aims to identify whether the association of CKD with HFpEF is independent of underlying echocardiographic abnormalities. Materials: We conducted a retrospective cohort study including patients without prevalent heart failure referred for echocardiography. Patients with serial echocardiograms, baseline left ventricular ejection fraction (LVEF) ≥50% and estimated glomerular filtration rate (eGFR) ≥90 mL/min/1.73 m2 were matched 1:1 with patients with eGFR <60 mL/min/1.73 m2 for age (±5 years), sex, history of hypertension or diabetes, use of renin-angiotensin inhibitors, and LVEF (±5%). A secondary analysis included patients with preserved LVEF and normal left ventricular mass index matched for the same parameters except use of renin-angiotensin inhibitors. Results: Patients with CKD were at increased risk for HFpEF admission: crude hazard ratio (HR) 1.79 (95% confidence interval [CI] 1.38–2.32, p < 0.001) and adjusted HR (for coronary disease, loop diuretics, left atrial diameter) 1.64 (95% CI 1.22–2.21, p = 0.001). LVEF and left ventricular diameter decreased over time in both groups but no difference was observed in rate of dropping. Results were similar in the secondary analysis (crude HR 1.99, 95% CI 1.07–3.71, p = 0.03 and HR adjusted for left atrial diameter 1.98, 95% CI 1.05–3.75, p = 0.04). Rate of change was similar for LVEF, pulmonary artery pressure, and left ventricular mass index in both groups. Conclusion: CKD is independently associated with incident HFpEF despite a similar change in relevant echocardiographic parameters in patients with or without CKD.
Lectotypification of the name Carex polycephala (Cyperaceae): an Eastern Himalayan endemic species

Authors: GHOSH ASOK , MALLICK TANMOY
Published: September 2019

The largest sedge (Cyperaceae) genus Carex Linnaeus (1753: 972) consists of ca. 2000 species worldwide (Reznicek 1990; Global Carex Group 2016). In India, 142 species of the genus were reported by Clarke (1894) and ca. 73 species are restricted to the North-Eastern part of India and Bhutan (Noltie 1993, 1994). The most recent estimate of the genus Carex of the Indian subcontinent, given by Govaerts et al. (2019+), is 219, however, in the Eastern Himalaya (EHM abbreviation according to Brummitt, 2001) the number of species is 122; 23 of which are endemic (Govaerts et al. 2019+). The name Carex polycephala Boott (1858: 4) has been applied to the species initially placed within the section or subgenus Carices Hymenochlaenae (Drejer 1844: 10) and subsequently in the subgenus Carex sect. Hymenochlaenae (Drejer) L. H. Bailey in Coulter (1885: 379); subgenus Carex sect. Hymenochlaenae subs. Longirostres Kükenthal (1909: 604). Mackenzie (1935: 297) raised its rank from subsection to sect. Longirostres and subsequently accepted by Hermann (1944: 148). The species is endemic to the Eastern Himalayas (Noltie 1993, 1994) and Sikkim and Assam (Kükenthal 1909). On the basis of previous morphological studies, the section Hymenochlaenae Drejer (1844) was considered as heterogeneous as was projected earlier by Ascherson & Graebner (1902-1904) and Mackenzie (1935). Members of the section are nested within multiple clades and considered as taxonomic dumping ground for “orphan” species (Global Carex Group 2016). Liang et al. (2010) considered the species as unranked “Taxa incertae sedis”. The species has not yet been evaluated in phylogenetic studies.
A new species of Heimioporus (Boletaceae) from southern China

Authors: CHEN XIANG-NYU , ZHANG MING , LI TAI-HUI , ZENG NIAN-KAI
Published: September 2019

Heimioporus sinensis, collected from tropical and subtropical areas of China, is introduced as a new species based on both morphological characters and molecular data. The species is characterized by the purplish red to deep magenta pileus, the reticulated stipe, the irregularly reticulate to reticulate-alveolate basidiospores 11.5–13.5 × 8–9.5 μm, and a trichodermal to intricately trichodermal pileipellis. Phylogenetic analyses based on the nuc 28S rDNA D1-D2 domains (28S) and the translation elongation factor 1-α gene (tef1-α) showed that H. sinensis is a distinct member of the genus Heimioporus in the subfamily Xerocomoideae.
Lectotypifications, new synonyms and new occurrences of Dalechampia L. (Euphorbiaceae) in Brazil

Authors: MENDES JONE CLEBSON RIBEIRO , SECCO RICARDO DE S. , BIGIO NARCISIO C. , ROSÁRIO ALESSANDRO S.
Published: September 2019

Three new occurrences of Dalechampia are reported, D. brownsbergensis, D. attenuistylus and D. heterobractea, of which one is a new record for Brazil. Dalechampia uleana and D. brevipedunculata are synonymized. The holotype of D. hastata is updated and lectotypes are designated for D. juruana. For the names D. cujabensis and D. magnoliifolia, a second-step lectotype are respectively designated. Morphologically similar taxa and the geographic distribution of each species are discussed. Recommendations for updating the list of Euphorbiaceae species for the Flora of Brazil 2020 project are also provided.
Notes on morphology and distribution of Acmanthera (A. Juss.) Griseb. (Malpighiaceae), an endemic genus from Brazil

Authors: FARROÑAY FRANCISCO , PERDIZ RICARDO DE OLIVEIRA , PRATA EDUARDO MAGALHÃES BORGES , VICENTINI ALBERTO
Published: September 2019

We present the amended description of the species Acmanthera minima and A. parviflora based on specimens collected in the Lower Negro River basin and the Serra do Aracá National Park, respectively, in the Amazonas State, Brazil. We also provide photographs, a distribution map, notes on conservation status and a key to all species of the genus Acmanthera. We report new records and range extension for Acmanthera latifolia and A. minima, previously known only for the Negro and Madeira River basins, respectively.
First record of Undabracon Quicke, 1986 (Hymenoptera: Braconidae, Braconinae) from the Indian subcontinent with the description of a new species
Authors: RANJITH A.P. , BELOKOBYLSKIJ SERGEY A. , NASSER M.
Published: September 2019

The Australasian braconine genus Undabracon Quicke, 1986 is recorded from the Indian subcontinent for the first time and we describe a new species, U. binduae Ranjith sp. nov. An illustrated key is provided for all the extant species together with the re-illustration of the species U. jacundus (Enderlein, 1920).
The ‘Logos’ of Faith in the Era of Pope Francis
Authors: Gamberini Paolo
Published: September 2019

Through globalization and greater exchange, religious identities are meeting and facing each other on a regular basis and in a very rapid way. As intercultural and religious plurality made possible the rise of Christianity, so in our age Christians must continue to be in dialogue with the secular world and other faith traditions, and be ready to move beyond an apologetic and exclusive form of self-understanding. Pope Francis’s magisterium is challenging the Catholic church to ‘reform’ its identity, envisioning the logos for Christian faith in discernment, reconciliation, and transformation, so that through a theology of encounter Christians will better understand their faith, redefine their confessional boundaries in a dialogical way, and become bridge-builders in our contemporary pluralistic society.
Not So Radical After All: Ideological Diversity Among Radical Right Supporters and Its Implications
Authors: Lancaster Caroline Marie
Published: September 2019

Radical right voters and parties are often characterized as conservative and traditionalist on issues of gender, sexuality, and morality. Common wisdom is that they reject the progressive sociopolitical shifts that began in the 1970s and early 1980s. However, some radical right parties, such as the Dutch Party for Freedom, maintain moderate positions on morality issues. Are radical right supporters still traditionalist? Latent class analysis applied to European Social Survey data from 10 West European countries reveals that radical right supporters belong to three ideologically distinct classes. The fastest growing group is the sexually-modern nativists, who make up about 45% by 2016. Contrary to extant literature, traditionalism no longer appears to be a major motivation for today’s radical right. Instead, immigration and nationalism are now the core common concerns for radical right supporters in Western Europe. This development may be due to the Euro crisis and the migration crisis, which have increased the salience of national borders.
Thermodynamic and kinetic parameters of polyester dyeing with Disperse Blue 56 using bio-based auxiliaries and co-solvent microemulsion
Authors: Radei Shahram , Carrión-Fité Francisco Javier , Ardanuy Mònica , Canal José María
Published: September 2019

The aim of the study was to dye polyester fabric with a low molecular weight anthraquinone type disperse dye (C.I. Disperse Blue 56), with n-butylacetate as co-solvent in the microemulsion system and the presence of two bio-based auxiliaries (ortho-vanillin and coumarin), at temperatures lower than 100℃. In order to investigate the influence of temperature and auxiliaries on the kinetic dyeing process, the energy of the activation was determined by the kinetic rates constants. The activated entropy values were obtained by the theory of absolute rates of dyeing and diffusion of the activated state of the dye for the disorder state of the dyeing system. Higher activated energies were found, as well as higher activated entropy, meaning higher dye absorption, for polyester samples dyed with ortho-vanillin/n-butylacetate compared with polyester samples dyed with coumarin/n-butylacetate. Color strength values of the polyester fabric dyed using the proposed microemulsion dyeing system at low temperature (95℃) were similar to polyester fabric dyed with a conventional dyeing system at high temperature (135℃). Regarding color fastness to washing and ironing, it was found that the use of the auxiliaries did not significantly modify the fastness values of the dyed samples.
Characteristics of the mud shale reservoirs in coal-bearing strata and resources evaluation in the eastern margin of the Ordos Basin, China
Authors: Chen Yue , Ma Dongmin , Xia Yucheng , Guo Chen , Yang Fu , Shao Kai
Published: September 2019

As the co-exploration and co-production of unconventional gas have become a new trend of the unconventional gas exploration and development in the eastern margin of the Ordos Basin, this study focuses on the distribution, pore characteristics, geochemical properties, and mineral composition of the mud shale in the coal-bearing strata. The results show that the mud shale in the coal-bearing strata is distributed relatively stably with an average cumulative thickness of 77.60 m and a buried depth of 200–2400 m, increasing from east to west. The total organic carbon content of mud shale is relatively high, ranging from 0.14% to 39.9%, and the thermal maturity ranges from 0.23% to 2.49%, affected by both buried depth and magmatic intrusion. The organic matter type of the mud shale is dominated by type III, favorable for gas generation. The mineral composition of mud shale is mainly clay minerals and quartz, with low brittle minerals content (averaging 30.34%) and high kaolinite content (averaging 59.23%). Pores and micro-fissures are relatively developed in the mud shale, dominated by intergranular pores, organic pores, and the micro-fissures developed between brittle mineral crystals, within crystals and between clay mineral particles, with a porosity of 1.05%–1.59% and a permeability of 0.001–0.142 (×10−3µm2). The specific surface area of pores in mud shale is 12.31–28.99 m2/g, and the total pore volume is 0.0146–0.0483 cm3/g. Mesopores and micropores (mainly slit shaped pores) provide the main pore volume of mud shale, and micropores contribute most of the specific surface area. The controlling factors on pore development include the total organic carbon, thermal maturity, and inorganic minerals composition. The total amount of shale gas resources is 2.49 × 1012 m3, and the Linxian-Xingxian area and Shilou-Daning area are the potential favorable zones for shale gas exploration and development.
Intravoxel incoherent motion magnetic resonance imaging for assessment of chronic pancreatitis with special focus on its early stage
Authors: Fujita Nobuhiro , Nishie Akihiro , Asayama Yoshiki , Ishigami Kousei , Fujimori Nao , Ito Tetsuhide , Honda Hiroshi
Published: September 2019

Background

It is clinically necessary to validate a new non-invasive and reliable imaging method to detect early chronic pancreatitis. Intravoxel incoherent motion magnetic resonance imaging (MRI) is useful for quantitative assessment in abdominal solid organs.

Purpose

To investigate the usefulness of intravoxel incoherent motion MRI parameters in the diagnosis of chronic pancreatitis.

Material and Methods

Sixty patients with early chronic pancreatitis (n = 44) and chronic pancreatitis (n = 16) were assessed with intravoxel incoherent motion imaging. For comparison, a control group of 71 individuals without chronic pancreatitis was also enrolled. The perfusion fraction (f), pseudo-diffusion coefficient (D*), true diffusion coefficient (D), and apparent diffusion coefficient of pancreatic parenchyma were calculated. These measurements were compared between the three groups. The diagnostic accuracy of imaging parameters was assessed.

Results

The f values of the early chronic pancreatitis group and the chronic pancreatitis group were significantly lower than those of the control group ( P < 0.001 and P < 0.001, respectively). The D* value of the chronic pancreatitis group was significantly lower than that of the early chronic pancreatitis group ( P = 0.0025). The D values of the early chronic pancreatitis group and the chronic pancreatitis group were significantly higher than those of the control group ( P = 0.001 and P = 0.001, respectively). The perfusion fraction showed the highest diagnostic performance with an Az value of 0.76 for discriminating the control group from the early chronic pancreatitis and chronic pancreatitis groups.

Conclusion

Intravoxel incoherent motion MRI parameters may reflect the minimal histological changes in early chronic pancreatitis.
Perception of task realism in mirror therapy activities for the upper extremity
Authors: Rowe Veronica T , Halverson Mallory , Wilbanks Laiken , Perry Shannon
Published: September 2019

Introduction

Mirror therapy is an effective stroke rehabilitation intervention for upper extremity hemiparesis; however, there are no established protocols of specific tasks for use during mirror therapy. Identifying the most realistic tasks would help establish a protocol for replicable research studies. The aim of this study is to describe characteristics of mirror therapy tasks that appear to be most realistic to healthy individuals.

Method

Ninety-two healthy individuals completed 25 tasks and movements with their dominant upper extremity reflected in a mirror. Participants rated each task for its perceived level of reality, or naturalistic appearance of a bilateral task as reflected in the mirror, by completing a task realism scale. Nonparametric analyses were used to compare tasks/movements designated as simple vs complex, functional vs range of motion/exercise, and performed parallel vs perpendicular to the mirror.

Results

Tasks categorized as simple and range of motion/exercise movements performed parallel to the mirror were rated as more realistic than tasks categorized as complex, involving functional tasks, or performed perpendicular to the mirror.

Conclusions

The findings of this study could potentially increase the efficacy of mirror therapy. Further research of this precursory assumption is needed in developing a standardized mirror therapy treatment protocol.
Reliability and validity of the Pediatric Clinical Assessment of Modes in outpatient pediatric rehabilitation
Authors: Popova Evguenia S , Ostrowski Rikki K , Wong Su Ren , Taylor Renee R
Published: September 2019

Introduction

Therapists’ interpersonal skills are important contributors to client participation. Providing therapists with opportunities to self-reflect on their approach to therapeutic communication can support occupational therapy best practice. The aim of this study was to evaluate the reliability and validity of the observer version of the Pediatric Clinical Assessment of Modes.

Method

The Pediatric Clinical Assessment of Modes was used to rate therapists’ overall and individual communication mode use according to the Intentional Relationship Model. Successful and unsuccessful attempts were rated separately.

Results

The observers rated 125 therapist–child interactions. The successful and unsuccessful domains of the Pediatric Clinical Assessment of Modes demonstrated appropriate internal consistency, inter-rater reliability, and structural validity for evaluating the therapist’s overall communication and individual use of the collaborating, empathizing, encouraging, instructing, and problem-solving modes. The empathizing, encouraging, and problem-solving subscales demonstrated greater than expected floor effects and could not effectively separate therapists into high and low performance groups for the unsuccessful domain. The observers reported low frequency of successful and unsuccessful communication attempts for the advocating subscale, raising concerns related to the reliability of this subscale for evaluating therapist–child interactions.

Conclusion

Study findings support the reliability and validity of the Pediatric Clinical Assessment of Modes for use in pediatric outpatient rehabilitation.
Preparation and in vivo evaluation of surface heparinized small diameter tissue engineered vascular scaffolds of poly(ε-caprolactone) embedded with collagen suture
Authors: Hui Xin , Geng Xue , Jia Liujun , Xu Zeqin , Ye Lin , Gu Yongquan , Zhang Ai-Ying , Feng Zeng-Guo
Published: September 2019

Herein biodegradable poly(ε-caprolactone) was electrospun into tubular microfibrous scaffolds and modified by the surface heparinization and wrapping of Type I collagen suture for enhancing anticoagulation activity and mechanical properties. The resulting scaffolds were featured by a double distribution of microfiber diameters ranged in 2.74 ± 0.44 and 5.15 ± 0.63 µm on the outer surface with tensile strength of 1.36 ± 0.37 MPa and Young’s modulus of 8.31 ± 1.87 MPa. The burst pressure after embedded with collagen suture was increased to 2419 ± 121 mmHg, remarkably higher than that of the poly(ε-caprolactone)-only scaffolds (1500 ± 136 mmHg) and native vessels. The scaffolds were evaluated in six rabbits for 20 weeks via a carotid artery interpositional model demonstrating a good patency. The effective cell infiltration, and rapid endothelialization and smooth muscle cell maturation were observed. There was no calcification in 20 weeks, and only one developed the aneurysm dilation after 16 weeks. It suggested that the surface heparinization is beneficial to improve the hydrophilicity and anticoagulation property of scaffolds, and embedment of collagen suture is useful to reinforce the mechanical properties and burst pressure.
Fabrication of carboxymethylcellulose hydrogel containing β-cyclodextrin–eugenol inclusion complexes for promoting diabetic wound healing
Authors: Li Mengdie , Li Fang , Wang Tao , Zhao Liang , Shi Yijie
Published: September 2019

The difficult healing of wounds caused by diabetes remains a challenging clinical problem. The activation of nuclear factor kappa-B as a key factor contributes to prolonged inflammation and inhibition of angiogenesis. As a natural antioxidant, eugenol may downregulate the lectin-like oxidized low-density lipoprotein receptor-1 and inhibit the activation of nuclear factor kappa-B in endothelial cells. However, eugenol shows poor solubility, pungent odor, and volatility, thus impeding its clinical application as a potential therapeutic agent. This study developed a novel bioactive carboxymethylcellulose hydrogel loaded with inclusion complexes of eugenol with β-cyclodextrin (eugenol–β-cyclodextrin/carboxymethylcellulose hydrogel) to regulate lectin-like oxidized low-density lipoprotein receptor-1-induced activation of nuclear factor kappa-B to enhance angiogenesis and inhibit inflammation for accelerating diabetic wound healing in vivo. It was found that eugenol–β-cyclodextrin/carboxymethylcellulose hydrogel exhibited remarkable antibacterial activity in vivo and in vitro. Furthermore, it accelerated diabetic wound healing by reducing the lectin-like oxidized low-density lipoprotein receptor-1/nuclear factor kappa-B-induced dysfunction in endothelial cells and promoting angiogenesis.
Sir William Osler (1849–1919) and God’s House in Ewelme
Authors: Connor Henry
Published: September 2019

When William Osler was appointed Regius Professor of Medicine in Oxford he also became, ex officio, Master of the Almshouse at Ewelme in Oxfordshire. The link with the Almshouse, its inmates and the villagers of Ewelme gave great pleasure to both Osler and his wife, who spent much time there. This paper explores reasons why Osler found the position so attractive and rewarding.
Book review: Chandra Sekharan, Assessment Centres for Talent Management: A Handbook for Identifying and Assessing Competencies and Developing Potential
Authors: Naib Sudhir
Published: September 2019

Chandra Sekharan, Assessment Centres for Talent Management: A Handbook for Identifying and Assessing Competencies and Developing Potential, 2018, New Delhi: Global Research Publications, 374 pp., ₹695. ISBN: 9788193342015.
Asiasiga i A’oga ma Nu’u: a child and adolescent post-tsunami intervention based on Indigenous Samoan values
Authors: Tamasese Taimalieutu Kiwi , Bush Allister , Parsons Tafaoimalo Loudeen , Sawrey Richard , Waldegrave Charles
Published: September 2019

Objective:

To describe a community-based single-session group intervention designed to address psychosocial needs of Samoan young people following a tsunami.

Method:

This programme resulted from collaboration between Samoan therapists, Samoan Catholic pastoral care workers and non-Samoan mental health clinicians. Informed by Samoan concepts of self and wellbeing, it incorporated cultural and spiritual practices familiar to Samoan young people and their families as well as body-centred therapeutic techniques, the ‘Tree of life’ exercise and provision of a cooked meal.

Results:

Following household visits to affected families in villages throughout southern and eastern Upolu and the island of Manono, the programme was devised and carried out in 11 villages with 1295 children participating. There was a high degree of acceptance of the programme by Pulenu’u (village governance leaders), young people, their families and community members.

Conclusions:

Interventions to address the psychological needs of Indigenous Pacific children and adolescents following a major disaster need to be embedded in the values of their communities. This paper describes an innovative programme based on Samoan values that was consistent with evidence-informed principles used to guide post-disaster responses.
Surface engineering analysis of plasma-nitrided die steels
Authors: Kumar Ashish , Kaur Manpreet , Joseph Alphonsa , Jhala Ghanshyam
Published: September 2019

In the current investigation, an effort was made to analyze the sliding wear and friction characteristics of the surface engineered hot forming tool steel. A surface treatment technique plasma nitriding was developed onto the surface of the hot forming tool steel namely AISI H13 with a view to reduce the friction coefficients and minimize wear. The treatment was done in various N2/H2 gas mixtures for the fixed time of 24 h and at a fixed temperature of 500 ℃. The phases formed on the plasma-nitrided surface have been identified by the X-ray diffraction technique. The surface morphology of nitrided specimens and the composition of the nitride particles have been analyzed using scanning electron microscopy/energy-dispersive spectroscopy techniques. Thereafter, the untreated and treated steel specimens were chosen to slide against high strength low alloy steel (actual workpiece material) at elevated temperatures. The tests were conducted on high-temperature tribometer under the constant load of 25 N at room temperature, 200 ℃, 400 ℃, and 600 ℃. The results have shown that the average friction coefficients and specific wear rate values decrease from room temperature to 400 ℃ and again increase at 600 ℃.
The use of cognitive screens within major trauma centres in England: A survey of current practice
Authors: Teager AJ , Methley A , Dawson B , Wilson H
Published: September 2019

Introduction

Major trauma centres are effective in reducing morbidity and mortality rates following serious injury. Many patients attending major trauma centres present with traumatic brain injuries, requiring specialist assessment in screening for potential cognitive deficits. Numerous cognitive screens exist but it is currently unclear which are used most frequently within major trauma centres. This study aimed to identify which screening tools are used most frequently in major trauma centres in England to enable discussion around their suitability for this clinical population.

Method

Electronic surveys were distributed via a mailing list to Clinical Psychologists and Clinical Neuropsychologists in major trauma centres across England to gather data on the use of cognitive screens.

Results

Fourteen Clinical Psychologists in Neuropsychology participated. Results suggest major trauma centres in England are currently using the ACE-III (50%) or MoCA (42%) as the most frequently used screens for cognitive difficulties following traumatic brain injury. Cognitive screening pathways are multi-disciplinary involving OTs (86%), psychologists (qualified 79%; assistant 57%) psychiatrists (36%), mental health nurses (7%) and therapy assistants (7%).

Conclusions

Major trauma centres are using evidence-based cognitive screens at present, but further work is needed to develop more effective, better validated cognitive screens for traumatic brain injury populations. Increased inter-professional discussion on the practice of cognitive screening would be beneficial for patients seen within major trauma centres.