bluuebunny/crossref_metadata_2025 huggingface dataset:
Farmyard Manure and Gypsum Effects on Soil pH and EC in a Semi-Arid Region of Kandahar, Afghanistan
Authors: Fazil Karamatullah , Seerat Wakil Ahmad , Nimgarai Hekmatullah , Haqmal Mohmmad Hanif
Published: November 2024

Soil alkalinity and salinity are the two main problems in Kandahar province, which cause poor crop growth and yield losses. FYM and gypsum can reduce soil alkalinity and salinity and gradually fix the mentioned problems. The application effects of these amendments have not been investigated before in this area. Therefore, a field experiment was conducted in the old city of Kandahar province in 2023 to assess the impacts of FYM and gypsum on soil pH and EC in the common bean field. The study utilized a split-plot design, with three main plots varying FYM application rates (0, 5, and 10 t ha-1) and three subplots representing different gypsum levels (0, 2, and 4 t ha-1). Results indicated that soil pH and EC were significantly decreased with the increasing addition of FYM and gypsum at all crop growth stages. The significantly lowest pH and EC values were recorded at the harvest stage with the addition of 10-ton FYM and 4.0-ton gypsum per hectare. Except for soil EC at 30 DAS, other interaction effects between FYM and gypsum on soil pH and EC were significant at all crop growth stages. The best treatment was a combination of 10 t ha-1 FYM and 4.0 t ha-1 gypsum, followed by 5.0 t ha-1 FYM and 4.0 t ha-1 gypsum, where the lowest pH and EC values were recorded. However, these results were found from a year-long experiment conducted in the old city of Kandahar province and may be recommended.
Performance of Agriculture Export Commodities from Afghanistan to World
Authors: Nasiri Ayaz Khan , Ahmadzai Khan Mohammad , Honaryar G
Published: November 2024

This study delves into the symmetric comparative advantage of agricultural products in Afghanistan using the Balassa index from 2011 to 2021 and Cuddy-Della Valle's formula to measure instability in time series data from 2008 to 2022. The study focuses on eight agricultural product groups, with cereals, dairy products, and tobacco having a negative comparative advantage. However, the study finds that Afghanistan can focus on producing fruits, pulses, nuts, and textiles due to their positive symmetric comparative advantage over time. The study also finds that India, Iran, and other countries have a higher instability index than Pakistan in terms of agricultural export commodities from Afghanistan. The findings suggest that Afghanistan should accelerate export promotion policies, increase participation in regional trade, and improve product quality to be competitive in regional and international markets. Additionally, there is high instability in agricultural exports to India, Iran, and other countries, urging Afghanistan to take steps for smoother agricultural exports to improve its economic position.
Constraints of Livestock Sector Development and Low Economic Contribution to The Economy of Afghanistan
Authors: Azizi Mohammad Naeem
Published: November 2024

This manuscript explores issues related to constraints of livestock sector development and low economic contribution to the economy of Afghanistan. Livestock is a fundamental part of agriculture with the contribution of live animals and their products. In Afghanistan, most of the country's poor people are living in rural areas that are primarily dependent on this sector. Meanwhile, food costs, in general, and livestock product prices determine the cost of living for the urban poor. The agriculture and livestock sector employs about 80% of the population in Afghanistan; therefore, the income per capita must be strongly influenced by the income levels of this sector. Animals are a source of human diets, income, and employment. Considering the large livestock population of Afghanistan, its contribution to the country's economy is still low. In contrast, the country has no clear, applicable policies and strategies for livestock development. The traditional methods of livestock management and production, poor feeding, minor health care, poor breeds, lack of suitable institutions and technologies, poor services and low capital investment in humans, and lack of development policies are becoming major factors in the poor performance of the livestock sector in Afghanistan. Despite some improvements in the livestock sector in recent years, the sector remains regressive. Thus, continuous assurance is needed to reduce the limitations and increase the sector's economic contribution. Afghanistan's development depends on rural residents’ financial self-sufficiency and high income.
Pentecostalism and Political Engagement in Ghana’s Fourth Republic
Authors: Kudadjie Patrick Tetteh
Published: November 2024

This paper analyses the nature of Pentecostal political engagement within Ghana’s Fourth Republic. It highlights the extent to which Pentecostal churches are fulfilling their divine mandate toward the state. Studies indicate that these churches are actively involved in the political sphere in this context. Methodologically, the study relies on a combination of secondary data, media reports, biblical texts, and personal observations, which are analysed qualitatively through a thematic lens. The findings reveal that their involvement takes shape in three primary forms: participation in the democratic process, socio-economic initiatives, and prophetic politicking. These aspects are assessed against the divine mandate concerning the church’s responsibilities to the state as articulated in Scripture. Overall, the study concludes that Pentecostal political engagement in Ghana’s Fourth Republic largely reflects their divine mandate. Additionally, the analysis underscores certain nuances and offers recommendations for enhancing their engagement.
Engaging Learners: Teaching English Through Interactive Games
Authors: Mammadova Rubaba
Published: November 2024

This study explores the integration of games as an effective strategy for teaching English as a second or foreign language. It focuses on three key activities—jigsaw puzzles, role-playing, and board games—and evaluates their impact on student engagement, language skills development, and knowledge retention. The findings reveal that games significantly enhance critical thinking, teamwork, speaking fluency, and vocabulary acquisition while creating an interactive and enjoyable learning environment. Although challenges such as ensuring equitable participation and providing clear instructions were identified, these can be addressed through careful planning and teacher training. The study also highlights the potential of digital game-based learning in expanding access to interactive education, particularly in remote and hybrid settings. This research emphasizes the transformative power of games in fostering not only linguistic proficiency but also a lifelong love for learning among students.
Housing project management by using fully fuzzy critical path problem
Authors: Ouda Eman , Hussein Iden
Published: November 2024

The pentagonal ranking function is one of the distinctive methods to solve fuzzy problems. The pentagonal membership function for the fuzzy number has been derived and laws have been obtained. The novel ranking pentagonal membership is utilized to solve the fully fuzzy critical path problem. The main aim of the research was to study the Al-Suwayra residential project in Iraq including studying the actual costs of the project and determining the minimum time period to complete it. The fully fuzzy critical path problem was implemented to find the minimum cost and time period to complete the project using the proposed ranking function. The paper includes practical example to find the minimum cost of residential building in the Al-Suwayra area in Iraq, as well as determining the optimal completion time for the project. The proposed technique was applied to the given example with accompanying tables to authenticate the precision of this approach, underscoring the efficiency and dependability of the proposed method. Over and above that, the results obtained were compared with the results of previous research in the literature.
UMA ANÁLISE DOS PRINCIPAIS EFEITOS JURÍDICOS DA ALIENAÇÃO PARENTAL NA LEGISLAÇÃO CIVIL BRASILEIRA
Authors: Lins Deborah Ben Accon Menezes
Published: November 2024

O ato proveniente praticado por um dos genitores ou por àqueles que tenham  autoridade sobre a criança ou o adolescente de modo a realizar interferência na  formação psicológica destes, levando-os a repudiar o outro genitor e gerando o  rompimento dos laços afetivos é definido como Alienação Parental. O objetivo geral  deste estudo foi conhecer a alienação parental e os aspectos que a cercam. A  metodologia utilizada neste estudo é a de revisão de literatura, do tipo narrativa. A  violação dos princípios garantidos para a criança e o adolescente como o direito à  dignidade, à convivência familiar, o princípio do melhor interesse, através da prática de  Alienação Parental acarreta sérios problemas psicológicos e sociais que muitas vezes  são irreversíveis. Dessa forma, nota-se que há dificuldade na aplicação da Lei pela  falta de conhecimento específico na psicologia para reconhecimento da existência ou  não de atos da alienação parental, podendo acarretar injustiças, tendo em vista que  muitas vezes o alienador utiliza o próprio Poder Judiciário para afastar o menor da  parte alienada.
FISIOTERAPIA PÉLVICA NA MULHER: AVALIAÇÃO E TRATAMENTO DA INCONTINÊNCIA URINÁRIA
Authors: Ramos Gisele Rodrigues , Silva Jenifer Farias Aristides da , Almeida Lorena de Oliveira , Campos Maria Eduarda Braine de , Gomes Mayara Gabriela Rosa , Rodrigues Renata , Martins Sandryelle , Rodrigues Laura de Moura , Cavalcante Fabrício Vieira
Published: November 2024

A fisioterapia na saúde da mulher é fundamental na prevenção e no tratamento da  diminuição da força do assoalho pélvico. Com o enfraquecimento dessa musculatura,  a mulher pode desenvolver disfunções sexuais, incontinência urinária, prolapso genital  e flacidez vaginal. O fisioterapeuta, com seu vasto conhecimento em fisiologia e  movimento, possui a capacidade de auxiliar na resolução dessas condições. Esta  pesquisa, uma revisão de literatura, tem como principal objetivo destacar a relevância  do tratamento e a importância do fisioterapeuta no manejo da incontinência urinária,  desde a percepção corporal até o tratamento propriamente dito. Os resultados  evidenciaram ampla concordância entre autores, destacando técnicas diversas para  o fortalecimento da musculatura do assoalho pélvico. Concluiu-se que a prevenção e  a aplicação da fisioterapia uroginecológica alcançam bons resultados na saúde e  qualidade de vida da mulher.
TÉCNICAS DE DESOBSTRUÇÃO DAS VIAS AÉREAS NA UNIDADE DE TERAPIA INTENSIVA NEONATAL: REVISÃO BIBLIOGRÁFICA
Authors: Castelhano Ana Dos Santos , Silva Tricia Marcela Cruz Da , Silva Maristela Prado e
Published: November 2024

A Fisioterapia Respiratória dentro das Unidades de Terapia Intensiva tem se  mostrado uma grande aliada na diminuição da morbimortalidade dos pacientes  submetidos a essa terapia. Esta revisão tem como objetivos mostrar a importância  das técnicas de desobstrução das vias aéreas realizada por fisioterapeuta, bem  como suas indicações e precauções em pacientes recém-nascidos internados  nessas unidades e em contrapartida descrever os procedimentos da fisioterapia  respiratória empregados na rotina hospitalar com esses pacientes neonatos. Essa  descrição foi embasada em artigos científicos e livros, os quais revelaram uma  diversidade de pesquisas sobre as intervenções desses profissionais dentro das  UTIs neonatal.
UMA ANÁLISE DO CONCEITO E DOS EFEITOS DO POLIAMOR NO DIREITO BRASILEIRO
Authors: Fialho Wener da Silva Ferreira
Published: November 2024

The research will analyze the concept and effects of polyamory in Brazilian law. The general objective is to analyze the legal challenges related to the institution of polyamory within the Brazilian legal system. The research problem is: How does Brazilian law recognize, protect and honor the diversity of family entities, beyond those based on monogamy, that are based on the sharing of affection and love? Polyamory is a form of romantic relationship in which individuals maintain multiple consensual romantic relationships simultaneously. This practice challenges traditional norms of monogamy and raises legal issues that need to be discussed in light of Brazilian law. In Brazil, the 1988 Federal Constitution guarantees all citizens the freedom to have relationships as they wish, as long as there is mutual respect and the rights of others are not violated. It is essential to promote a dialogue between the legislature, academia and civil society so that a regulatory framework can be built that encompasses the different ways of loving and forming a family. The recognition of polyamory in Brazilian law, therefore, is an essential step towards building a legal system that respects the diversity of human experiences and promotes social justice.
ERROS NO MANEJO NUTRICIONAL DE PSITACÍDEOS CRIADOS EM CATIVEIRO
Authors: Costa Yasmin Oliveira Da , Barbosa Fernanda Borges
Published: November 2024

Inadequate nutrition of captive psittacines is a frequent problem and is associated with several errors, such as diets rich in oilseeds and the lack of adequate supplementation. These errors can result in serious health conditions, including hepatic lipidosis, hypovitaminosis A, and hypocalcemia, affecting the well-being and longevity of these birds. The objective of this study is to evaluate, through field research, the knowledge of guardians about nutrition, identifying failures in feeding management and the risks associated with the provision of inadequate or toxic foods. In addition, this study also discusses the main errors in the nutritional management of psittacines, the specific needs of macronutrients and micronutrients, and the risks associated with the provision of inadequate or toxic foods. It also addresses the biological, feeding, and conservation characteristics of the order Psittaciformes, composed of parrots, macaws, and parakeets, and how inadequate management practices affect the behavior and health of these birds. Most participants reported feeding commercial feed to their birds, with 33% also feeding seed mixes, which are rich in oils and can cause liver disease. The results emphasize that the use of formulated feeds and the controlled supply of fruits, vegetables, and adequate supplementation can prevent nutritional problems and ensure the long-term health of captive parrots.
TÉCNICAS DE REPRODUÇÃO ASSISTIDA: ÊNFASE EM FERTILIZAÇÃO IN VITRO E INJEÇÃO INTRACITOPLASMÁTICA DE ESPERMATOZOIDES
Authors: Rocha Carolina , Favere Eduarda De , Neri Mariana da Silva
Published: November 2024

This work sought to study the main aspects of human reproduction, addressing questions, methods and analyzing its technical processes, its indications, and the expected results in cases of severe infertility. The research includes an analysis of the stages of fertilization, and current reproductive technologies, such as in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI) and used a literature review to demonstrate the advantages and disadvantages of each method and how Health conditions can affect reproductive capacity. It was also observed the biological processes involved, as well as the social and ethical implications. Thus, through a literature review, the work aimed to offer a comprehensive view of human reproduction, highlighting the importance of understanding the factors that affect fertility. It also sought to highlight how reproduction methods can help couples who face difficulties in searching for appropriate treatments to expand the possibilities of conception based on the various reproductive options, considering their limitations and factors such as age, health and personal circumstances.
APLICAÇÃO DA METODOLOGIA LEAN CONSTRUCTION NO PROCESSO EXECUTIVO DOS KITS ELÉTRICOS DE UMA EDIFICAÇÃO RESIDENCIAL DE ESTRUTURA MONOLÍTICA MOLDADA IN-LOCO LOCALIZADA NA CIDADE DE MANAUS ESTADO DO AMAZONAS
Authors: Pereira Adriano Gomes , Miranda Walzenira Parente
Published: November 2024

Lean Construction, a methodology that has gained prominence in civil construction for its potential to optimize processes and increase productivity. By focusing on reducing waste and maximizing efficiency, Lean seeks to improve the workflow in construction activities, avoiding interruptions and unnecessary rework. This approach has been continuously studied, as its adaptation to the construction context is relatively recent, requiring analyzes on how its techniques can be implemented effectively at each stage of the construction process. This work aims to show the executive process of installing electrical kits through the applicability of the Lean tool. The analysis will be applied to a five-story residential building, with a self-supporting structure and cast in situ. The focus will be on the installation of electrical kits, examining each phase of the executive process and highlighting how Lean better structures the steps and workflows, speeds up execution and makes the work more productive. The analysis will demonstrate that, with the Lean methodology, it is possible to significantly increase the pace of activities, providing a more fluid and organized execution, reinforcing the importance of this method as a valuable tool for advancing productivity in construction.
CRIMINALIDADE EM RONDÔNIA: UMA ANÁLISE ACERCA DA RELAÇÃO ENTRE EDUCAÇÃO E CRIMINALIDADE NO ESTADO DE RONDÔNIA E A LEI DE EXECUÇÃO PENAL
Authors: Souza Gabriele Pereira de , Ugalde Júlio César Rodrigues
Published: November 2024

The main goal of the present article is to analyze the relationship between education and crime in the state of Rondônia, once crime is about a socioeconomic and educational question. The main goal of the present article is to analyze the relationship between education and crime in the state of Rondonia, once crime is about a socioeconomic and educational question. In addition, this article is to demonstrate the importance of education in the Rondonia state prison system as one of the scientific tools to the crime crime, for both here will also be examined the state of Education for Private people and Egresses of the Private State State and Egress of the Rondonia State State of the State State of the State of the Rondonia State System of the State State and Egresses of the Rondonia State State. That way, the present used the descriptive and exploratory method.
The Role of Green Technologies in Mitigating Carbon Footprints in Industrial Sectors
Authors: Al Barazanchi Israa Ibraheem , Rasheed Dima Haider
Published: November 2024

Due to energy-intensive processes, dependence on fossil fuels and poor waste management, industry is among the largest contributors to global carbon emissions This environment this growing environmental problem highlights the urgent need for sustainable solutions to reduce carbon emissions. This study examines the role of green technologies in addressing these challenges, focusing on renewable energy systems, carbon capture and storage (CCS), circular economic practices, and digital products on the other hand. The main objective is to assess how these technologies can reduce greenhouse gas emissions and increase energy efficiency and potentially increase the industrial sustainability of resources activities in the field. Findings show that integrating green technologies can lead to a 25% reduction in energy consumption, 85% efficiency in carbon capture, and greenhouse gas emissions has decreased by 50% in a decade Furthermore, sustainable materials and energy efficiency solutions promise to reduce waste and improve the relative quality of infrastructure use Display results. Despite constraints such as high start-up costs and technical barriers, the study highlights the significant potential of green innovation to transform technology It provides a call to action for businesses , policy makers and consumers to embrace this technology as a means to achieve global sustainability goals ends.
GESTÃO DE RISCOS EM FATORES HUMANOS: FADIGA, DESEMPENHO E SEGURANÇA EM OPERAÇÕES ESPACIAIS
Authors: Valente Bruno Torido Serra , Pereira Ísis Beltrão
Published: November 2024

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MURAKKAB TUZILMALI KALIY QATLAMLARINI FIZIK VA MEXANIK XUSUSIYATLARNI HISOBGA OLGAN HOLDA BUZILISH REJIMLARI
Authors:   Qarshi muhandislik-iqtisodiyot instituti dotsenti, Qarshi, O‘zbekiston, Xujakulov Amirjon Murodovich , Olimov Farusxon Muzaffar o‘g‘li ,   Qarshi muhandislik-iqtisodiyot instituti dotsenti, Qarshi, O‘zbekiston, Nomdorov Rustam Uralovich ,   Qarshi muhandislik-iqtisodiyot instituti dotsenti, Qarshi, O‘zbekiston, Haqberdiyev Dilshod Qodir o‘g‘li ,   Qarshi muhandislik-iqtisodiyot instituti assistenti,  Qarshi, O‘zbekiston
Published: November 2024

Tepaqo‘ton tog‘-kon majmuasidan qazib olingan foydali qazilmaning fizik, maxanik, kon-texnik va kon-texnologik xossalari aniqlangan. Shu bilan bir qatorda lahimlarning xizmat muddatini va turg‘unligini oshirish bo‘yicha asoslangan takliflar ishlab chiqilgan.
Kon lahimlarida kuzatilayotgan buzilishlarni kelib chiqish sabablari aniqlangan. Qazib olingan silvinit qatlamlaridagi buzilishlar strukturasi qazilgan qatlamning gipsometriyasiga, asosiy jinslarning qazish oʻlchamiga, qatlam qalinligiga, qatlamning yotish chuqurligiga bogʻliq boʻlib, bu parametrlarni aniqlash natijalari asosida buzilish rejimlarini aniqlash imkonini beradi.
Kon lahimlarining chegarasidagi buzilishlarga ta’sir qiluvchi omillar quyidagilardan iboratdir: tog‘ jinslarining grаvitаtsiоn хususiyatlаri, lahim shifti va ostidagi tog‘ jinslarining gidravlik, fizik, mexanik, kon-texnik, kon-texnologik xossalari va kristall pаnjаrаgа kiruvchi zаrrаchаlаr оrаsidаgi bоg’liqlik kuchi hamda kimyoviy tаrkibi.
QISHLОQ ХО‘JАLIGI TЕХNIKАLАRIDАN FОYDАLАNISH ХАVFSIZLIGINI TIZIMLI BОSHQАRISH TАLАBLАRI
Authors:   Mustаqil tаdqiqоtсhi, Qаrshi muhаndislik-iqtisоdiуоt instituti, Qаrshi, Оʻzbеkistоn, Kаrimоv Bаhоdir О‘ktаmо‘g‘li
Published: November 2024

Mаqоlаdа qishlоq хо‘jаligi tехnikаlаridаn fоуdаlаnish хаvfsizligini tizimli bоshqаrishning аsоsiу vаzifаsi, mаqsаdi tаhlil qilingаn, qishlоq хо‘jаligi tехnikаlаridаn fоуdаlаnishdаgi хаvfsizlik tаlаblаrini tаsnifi vа “Insоn-mаshinа-muhit” tizimidа qishlоq хо‘jаlik mаshinаlаri хаvfsizligini tа’minlоvсhi аsоsiу kоmpоnеntlаr tа’siridа bахtsiz hоdisаlаrni kеlib сhiqish еhtimоlligi аlgоritmi ishlаb сhiqilgаn. “Insоn-mаshinа-muhit” tizimidаgi bахtsiz hоdisаlаrgа оlib kеluvсhi sаbаblаrni (insоn оmili, qishlоq хо‘jаlik tехnikаlаri kоnstruksiуаsi vа ulаrdаn fоуdаlаnishgа qо‘уilgаn хаvfsizlik tаlаblаri, ishlаb сhiqаrish muhitit оmillаri) bittа tizim sifаtidа qаbul qilish tаvsiуа еtildi.
Standardizing and Enhancing the Tracking of Continuing Medical Education (CME) within Graduate Medical Education (GME) Programs: A Comprehensive Analysis
Authors: Miller, C-TAGME, CHPM Dora
Published: November 2024

Continuing Medical Education (CME) is crucial for the professional development of physicians and allied healthcare professionals, ensuring they maintain and update their skills to provide high-quality patient care. In Graduate Medical Education (GME) programs, CME supports the training of medical residents and fellows as they transition to independent practice. However, challenges in tracking, documenting, and verifying CME activities persist, hindering the assessment of trainees’ progress and the identification of learning gaps. This study analyzes the current state of CME tracking in GME programs, exploring the challenges faced by program directors, educators, and trainees. It aims to identify strategies for standardizing and improving CME tracking, including digital platforms, centralized databases, and needs assessments. By reviewing literature, case studies, and real-world experiences, the study provides insights and recommendations for optimizing CME management.

The search yielded a diverse range of research approaches, encompassing commentary/opinion articles, conference reports, literature reviews, and tracking in GME. Ensuring activities are relevant, engaging, and effective in enhancing the overall educational experience of medical trainees.

However, tracking, and documenting CME activities for trainees pose significant challenges due to the lack of a standardized system. This study aims to analyze the current state of CME tracking within GME programs, identify challenges, and propose strategies for improvement. By reviewing literature, case studies, and real-world experiences, the study will explore methods such as digital platforms and centralized databases to enhance CME tracking, ultimately improving medical education and patient care.
Creation of the "Forum for United Leaders in Graduate Medical Education" (FULGME)
Authors: Furneaux, MHA Pamela , Gohre, BSHA, CHPM, CLSSBB Barbara
Published: November 2024

The Forum for United Leaders in Graduate Medical Education (FULGME) is an innovative initiative designed to bring together a diverse array of professionals within the medical education sector. This forum aims to create a collaborative environment where Program Administrators, Program Managers, and GME Leaders can share their insights, best practices, and research. By fostering a community dedicated to high- quality research dissemination, critical inquiry, and peer-review, FULGME seeks to elevate the standards of graduate medical education. The establishment of this forum is driven by the need for a centralized platform that promotes professional development, leadership, and the continuous improvement of medical education. Through a national survey conducted in December 2023, it was evident that there is a strong demand for such a platform, with over 95% of respondents supporting the creation of FULGME. This initiative marks a significant step towards enhancing the quality and inclusivity of medical education, ensuring that all voices within the community are heard and valued.
Expanding the Connection Between Cognition and Illness Intrusiveness in Multiple Sclerosis
Authors: Gangi Aprille , Raskin Sarah A. , Turner Aaron P. , Foley Frederick W. , Neto Lindsay O. , Gromisch Elizabeth S.
Published: November 2024

BACKGROUND:

Multiple sclerosis (MS) disease factors, such as cognitive impairment, can cause disruptions in meaningful activities, also known as illness intrusiveness. Although the association between specific objective measures of cognition and illness intrusiveness has been documented in MS, the contributions of individuals’ perceptions of their cognition or whether any psychological factors can buffer the relationship have yet to be explored. This study aimed to (1) simultaneously examine objective processing speed and subjective cognition as disease factors contributing to illness intrusiveness and (2) explore whether resilience moderates the relationship between cognition and illness intrusiveness.

METHODS:

Participants (N = 112) were individuals with MS who completed the Illness Intrusiveness Ratings Scale (IIRS), Symbol Digit Modalities Test (SDMT), Perceived Deficits Questionnaire (PDQ), and MS Resiliency Scale (MSRS) as part of a larger cross-sectional study. A hierarchical linear regression was done, followed by individual moderation analyses.

RESULTS:

Both the PDQ (b = .43, P = .001) and SDMT (b = −4.17, P = .003) were independent predictors of the IIRS. There was no evidence of moderation in either model, although the MSRS independently contributed to the IIRS.

CONCLUSIONS:

Among individuals with MS, objective processing speed and subjective cognition were independently associated with illness intrusiveness, highlighting the importance of considering both cognitive performance and perceptions as contributing factors to life disruptions.
La mujer bajo la violencia simbólica en Las polacas de Patricia Suárez
Authors: Capała Bartłomiej
Published: November 2024

El presente trabajo propone un acercamiento al ciclo dramático Las polacas de Patri-cia Suárez desde la perspectiva de la violencia simbólica, un concepto acuñado por Pierre Bourdieu, y su presencia en la red de operaciones propias de la trata de blancas. Con apoyo en los estudios de Eva Illouz y Sara Ahmed, se examina el aspecto seduc-tivo del matrimonio y la promesa de una vida feliz que despliega el discurso social ante las mujeres con el objetivo de controlar sus cuerpos. En esta misma línea y recu-rriendo a la teoría de Bourdieu, se analiza el proceso de mercantilización del cuerpo femenino y su circulación en el mercado matrimonial y simbólico. Se resalta espe-cialmente cómo se manifiesta la violencia simbólica en el contexto de la trata de blancas, tanto en la línea hombre-mujer como mujer-mujer. Finalmente, se pone un acento especial en la pobreza como un factor clave de la violencia simbólica.
Stosunki chińsko-wenezuelskie w okresie prezydentury Cháveza i Maduro
Authors: Bonder Weronika
Published: November 2024

Niniejszy artykuł poddaje analizie politykę zagraniczną Wenezueli od roku 1999 oraz odzwierciedla charakter chińskiej polityki zagranicznej. Ma on na celu scharakteryzowanie stosunków chińsko-wenezuelskich, szczególnie uwzględniając wzajemne znaczenie tych państw, a także ukazując stosunki Chin z Ameryką Łacińską przez pryzmat relacji prowadzącej od przyjaźni do uzależnienia. Kluczowe znaczenie mają również podobne wartości wyznawane zarówno przez Chiny, jak i kraje Ameryki Łacińskiej. Wykorzystując możliwość prześledzenia łańcucha przyczynowo-skutkowego między zmiennymi zależnymi a zmiennymi niezależnymi autorka twier-dzi, że znaczący wpływ na wzajemne stosunki miała nie tylko specyfika rządów Hu-gona Chaveza i Nicolasa Maduro, ale również zastosowanie konkretnych narzędzi dyplomatycznych przez Chiny.
Power spectrum based early warning signal of neuronal firing
Authors: LI Songwei , XIE yong ,   Shaanxi Engineering Research Center of Nondestructive Testing and Structural Integrity Evaluation, State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi’an Jiaotong University, Xi’an 710049, China
Published: November 2024

Brain diseases often occur simultaneously with critical changes in neural system and abnormal neuronal firing. Studying the early warning signals (EWSs) of critical changes can provide a promising approach for predicting neuronal firing behaviors, which is conducible to the early diagnosis and prevention of brain diseases. Traditional EWSs, such as autocorrelation and variance, have been widely used to detect the critical transitions in various dynamical systems. However, these methods have limitations in distinguishing different types of bifurcations. In contrast, the EWSs with power spectrum have shown a significant advantage in not only predicting bifurcation points but also distinguishing the types of bifurcations involved. Previous studies have demonstrated its predictive capability in climate and ecological models. Based on this, this study applies the EWS with power spectrum to neuronal systems in order to predict the neuronal firing behaviors and distinguish different classes of neuronal excitability. Specifically, we compute the EWSs before the occurrence of saddle-node bifurcation on the invariant circle and subcritical Hopf bifurcation in the Morris-Lecar neuron model. Additionally, we extend the analysis to the Hindmarsh-Rose model, calculating the EWSs before both saddle-node bifurcation and supercritical Hopf bifurcation. This study contains the four types of codimension-1 bifurcations corresponding to the neuronal firing. For comparison, we also calculate two types of conventional EWSs: lag-1 autocorrelation and variance. In numerical simulations, the stochastic differential equations are simulated by the Euler-Maruyama method. Then, the simulated responses are detrended by the Lowess filter. Finally, the EWSs are calculated by using the rolling window method to ensure the detection of EWS before bifurcation points. Our results show that the EWS with power spectrum can effectively predict the bifurcation points, which means that it can predict neuronal firing activities. Compared with the lag-1 autocorrelation and the variance, the EWSs with power spectrum not only accurately predict the neuronal firing, but also distinguish the classes of excitability in neurons. That is, according to the different characteristics of the power spectrum frequencies, the EWS with power spectrum can effectively distinguish between saddle-node bifurcations and Hopf bifurcations during neuronal firing. This work provides a novel approach for predicting the critical transitions in neural system, with potential applications in diagnosing and treating brain diseases.
Monophonic domination polynomial of the path graph
Authors: Arul Paul Sudhahar P. , Jebi W.
Published: November 2024

Let $MD(G, i)$ be the family of monophonic dominating sets of a graph $G$ with cardinality $i$ and let $\md(G, i) = |MD(G, i)|$. Then the monophonic domination polynomial $MD(G, x)$ of $G$ is defined as $MD(G, x) = \sum_{i = \gamma_m(G)}^{p}  \md(G, i) x^i$, where $\gamma_m(G)$ is the monophonic domination number of $G$. In this paper we have determined the family of monophonic dominating sets of the path graph $P_n$ with cardinality $i$. Also, the monophonic domination polynomial of the path graph is calculated and some properties of the coefficient $\md(P_n, i)$ is discussed.
Integrated Analysis of Single-Cell and Bulk RNA-Seq Data reveals that Ferroptosis-Related Genes Mediated the Tumor Microenvironment predicts Prognosis, and guides Drug Selection in Triple-Negative Breast Cancer
Authors: Gong Xuantong , Gu Lishuang , Yang Di , He Yu , Li Qian , Qin Hao , Wang Yong
Published: November 2024

TNBC is aggressive, lacking methods to predict recurrence and drug sensitivity. Ferroptotic heterogeneity varies in TNBC subtypes. However, the TME mediated by ferroptosis genes is unclear. Our study aims to integrate single-cell and bulk RNA-seq data to reveal the ferroptosis-mediated TME in TNBC, predicting prognosis and guiding treatment.The single-cell RNA-seq (scRNA-seq) and bulk RNA-seq data of TNBC were sourced from the Gene Expression Omnibus (GEO) database. Using these data, a machine learning algorithm was employed to integrate and analyze the characteristics of the TME mediated by ferroptosis-related genes in TNBC. Prediction models for TNBC survival prognosis and drug treatment response were established and then validated in an independent set.At the individual cell level, T cells were categorized into three distinct subpopulations, and local macrophages into two subpopulations. The infiltration degree of these different cell subpopulations was closely associated with prognosis and treatment outcomes. Based on this, the risk score model we developed effectively predicted recurrence-free survival in TNBC patients, with independently validated pooled predicted 3-, 4-, and 5-year Area Under the Curves(AUCs) of 0.65, 0.67, and 0.71, respectively. Additionally, we found that patients in the high-risk group may be more responsive to 27 drugs.We have uncovered the tumor immune cell clusters in TNBC mediated by ferroptosis. A risk score model was constructed to identify high-risk TNBC patients, which can assist physicians in disease monitoring and precision therapy. The genes identified hold significant potential as therapeutic targets for TNBC patients.This project is funded by the National Natural Science Foundation of China (81974268, 82304151), the Talent Incentive Program of Cancer Hospital Chinese, Academy of Medical Sciences (801032247), the Cancer Hospital of Chinese Academy of Medical Sciences-Shenzhen Hospital Cooperation Fund (CFA202202023), and the open project of Beijing Key Laboratory of Tumor Invasion and Metastasis Mechanism, Capital Medical University(2023ZLKF03).
GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine
Authors: Yamamoto Takashi , Ueji Kayoko , Mizuta Haruno , Inui-Yamamoto Chizuko , Kumamoto Natsuko , Shibata Yasuhiro , Ugawa Shinya
Published: November 2024

The concept of kokumi, which refers to an enhanced and more delicious flavor of food, has recently generated considerable interest in food science. However, kokumi has not been well studied in gustatory physiology, and the underlying neuroscientific mechanisms remain largely unexplored. Our previous research demonstrated that ornithine (L-ornithine), which is abundant in shijimi clams, enhanced taste preferences in mice. The present study aimed to build on these findings and investigate the mechanisms responsible for kokumi in rats. In two-bottle preference tests, the addition of ornithine, at a low concentration that did not increase the favorability of this substance alone, enhanced the preferences of animals for umami, sweet, fatty, salty, and bitter solutions, with the intake of monosodium glutamate showing the most significant increase. Additionally, a mixture of umami and ornithine synergistically induced significant responses in the chorda tympani nerve, which transmits taste information to the brain from the anterior part of the tongue. The observed preference enhancement and increase in taste-nerve response were abolished by antagonists of the G-protein-coupled receptor family C group 6 subtype A (GPRC6A). Furthermore, immunohistochemical analysis indicated that GPRC6A was expressed in a subset of type II taste cells in rat fungiform papillae. These results provide new insights into flavor-enhancement mechanisms, confirming that ornithine is a kokumi substance and GPRC6A is a novel kokumi receptor.
Primosomal protein PriC rescues replication initiation stress by bypassing the DnaA-DnaB interaction step for DnaB helicase loading at oriC
Authors: Yoshida Ryusei , Korogi Kazuma , Wu Qinfei , Ozaki Shogo , Katayama Tsutomu
Published: November 2024

In
Escherichia coli
, replisome and replication fork assembly are initiated by DnaB helicase loading at the chromosomal origin
oriC
via its interactions with the DnaA initiator and the DnaC helicase loader. Upon replication fork arrest, the replisome including DnaB dissociates from the stalled fork. Replication fork progression is rescued by primosomal protein PriA- or PriC-dependent pathway in which PriA and PriC promote reloading of DnaB in different mechanisms. However, the mechanism responsible for rescue of blocked replication initiation at
oriC
remains unclear. Here, we found that PriC rescued blocked replication initiation in cells expressing an initiation-specific DnaC mutant, in mutant cells defective in DnaA-DnaB interactions, and in cells containing truncated
oriC
sequence variants. PriC rescued DnaB loading at
oriC
even in the absence of Rep helicase, a stimulator of the PriC-dependent replication fork restart pathway. These and results of
in vitro
reconstituted assays concordantly suggest that this initiation-specific rescue mechanism provides a bypass of the DnaA-DnaB interaction for DnaB loading by PriC-promoted loading of DnaB to the unwound
oriC
region. These findings expand understanding of mechanisms sustaining the robustness of replication initiation and specific roles for PriC in the genome maintenance.
Annihilation of action potentials induces electrical coupling between neurons
Authors: Schlötter Moritz , Maret Georg , Kleineidam Christoph J
Published: November 2024

Neurons generate and propagate electrical pulses called action potentials which annihilate on arrival at the axon terminal. We measure the extracellular electric field generated by propagating and annihilating action potentials and find that on annihilation, action potentials expel a local discharge. The discharge at the axon terminal generates an inhomogeneous electric field that immediately influences target neurons and thus provokes ephaptic coupling. Our measurements are quantitatively verified by a powerful analytical model which reveals excitation and inhibition in target neurons, depending on position and morphology of the source-target arrangement. Our model is in full agreement with experimental findings on ephaptic coupling at the well-studied Basket cell - Purkinje cell synapse. It is able to predict ephaptic coupling for any other synaptic geometry as illustrated by a few examples.
Unraveling Aircraft Flutter: The Role of Structural Actuator Saturation in Aeroelastic Instabilities
Authors: Sousa Marcelo Santiago de , Siqueira Luiz Felipi Ribeiro , Rodrigues José Junior Leão , Cardoso-Ribeiro Flávio Luiz
Published: November 2024

This article presents a new concept that can be used to explain the physical mechanism that causes flutter: the concept of the structural actuator and the effects of its saturation on the aeroelastic stability of an aircraft. One detailed physical mechanism that could be the cause of a flutter, that occurred during the numerical simulation of an aircraft, is presented. Each aeroelastic mode consists of torsional and rotational movements. These two movements in each mode were dissociated and the amplitude and phase of each movement were analyzed along with the damping and frequency of the mode. The structural resistances of torsion and bending, as well as the bending movement itself, have a damping effect and torsion has an destabilizing effect on the oscillations (if the centre of pressure is ahead of the flexural axis). After a certain speed, bending becomes out of phase with the applied forces. At this point, the bending has an amplifying effect on the oscillations and only the structural stiffness dampens the movement. From the speed at which the bending movement is out of phase with the applied aerodynamic loads, the damping of the mode decreases with speed, until flutter occurs. One possible physical explanation for this sudden change of phase in bending can be attributed to the structural uncapacity to follow the higher frequency movements demanded on the structure. The real movement has an rate lower than the commanded. This difference can cause an gain and phase variation, similar to ones that occurs in actuators of flight control surfaces when they arrive on the onset frequency. Considering the structural wings are seen as physical actuators that moves the aerodynamic surfaces, if the phase difference comes close to 180 deg, the bending becomes one destabilizing movement, that is amplified with the airspeed. This causes a decreasing on the damping ratio until the flutter occurs. This idea is detailed presented in this paper.
Impact on farm Income by Jalasamrudhi Project, Thiruvananthapuram, India
Authors: Anjana P. M. , T. P. Lazarus, , A. Vijayan, , S. K. Raj, , P. P. Gopinath,
Published: November 2024

The study analysed the impact of the Jalasamrudhi watershed development programme on farm income. The data regarding the crops and income were collected from the Kattakada legislative constituency of the Jalasamrudhi Project, Thiruvananthapuram. A systematic sampling technique was adopted for the data collection and information was collected from 80 beneficiaries and 80 non-beneficiaries of the project, thus bringing the total sample size to 160. In addition to the watershed development programme implemented by Jalasamrudhi project, the beneficiaries of the project received one cattle per person and five poultry birds per person, enhancing their livelihoods and agricultural capabilities in the Kattakada constituency of the Jalasamrudhi Project in Thiruvananthapuram. Thus, the beneficiaries benefited from increase in an adoption of the water conservation measures and net farm income.
Ecological Study and Phytochemical Analysis of Ageratum conyzoides in Three Selected States of South-East Nigeria
Authors: Chibuzo Anyanele Wisdom , Ikechukwu Izundu Alexander , Sussan Ezenwata Ifeoma , Anthonia Ezeabara Chinelo , Sylvalyn Anyanele Ijeoma , Ann Mbaukwu Onyinye , Amaka Egbe Patricia , Patrick Nwaogaranya Uche
Published: November 2024

Ageratum conyzoides is an annual herbaceous plant of American origin with a pantropical distribution. It belongs to the Asteraceae family. It owns a reputed history of indigenous remedial uses, including as a wound dressing, an antimicrobial, and mouthwash as well as in treatment of dysentery, diarrhea, skin diseases, etc. The plant has unique biological attributes and a raft of miscellaneous chemical compounds that render it a pharmacologically important herb. Ageratum conyzoides was gotten from three different states namely: Anambra, Enugu, and Imo state. They were air dried for seven days and taken to the laboratory for proper phytochemical screening. Ecological study on Ageratum conyzoides was also carried out. When the test for phytochemical constituent was carried out, the result of preliminary phytochemical analysis of Ageratum conyzoides showed that saponin, flavonoid, alkaloid, tannin, terpenoids, glycosides, carbohydrates, anthraquinones, and phenol were present in the three states while steroids, proteins, oil and resin, and reducing sugar were absent in the three states. The result for the ecological study of A. conyzoides in the three states showed that A. conyzoides has the highest species diversity, followed by Enugu, and then Imo state. The mean value of the species diversity is 2.09. The analysis of variance from the photochemical screening showed a significant difference in the percentage quantitative phytochemical composition between states and between extracts (p<0.05), while the species diversities are not significantly different from one another which show the homogeneity of the three states.
The Role of Artificial Intelligence (AI) in Enhancing Cybersecurity for Educational Technologies in US Public Schools
Authors: Obioha-Val Onyinye
Published: November 2024

This study investigates the role of Artificial Intelligence (AI) in enhancing cybersecurity for U.S. public schools, with the primary objective of evaluating AI's effectiveness in reducing cyber threats and safeguarding student privacy. Specifically, the study assesses AI-driven security systems such as threat detection and anomaly detection algorithms, which help schools monitor network traffic and identify potential breaches in real-time. Using logistic regression on data from the K-12 Cybersecurity Resource Center, findings reveal that schools implementing AI solutions are 75% less likely to experience cyber breaches (p < 0.001), highlighting AI's protective impact. Furthermore, a comparative analysis of FERPA and COPPA compliance reports highlights a substantial reduction in privacy violations among AI-using schools, with an average of 0.57 violations per school, compared to 1.50 in schools without AI. A K-means cluster analysis identified budget constraints (65.75%) and IT staff shortages (55.25%) as primary barriers to AI adoption. To address these obstacles, the study recommends phased technology upgrades and increased funding for workforce training as critical strategies to facilitate AI integration and enhance cybersecurity across educational institutions. These strategic interventions are essential for optimizing the effectiveness of AI-driven security systems, making it feasible for resource-constrained schools to adopt and maintain advanced cybersecurity measures. The study’s findings contribute to the growing body of knowledge on educational cybersecurity and provide actionable insights for policymakers and administrators seeking to strengthen data protection and privacy in school environments.