bluuebunny/crossref_metadata_2025 huggingface dataset:
Imagens do corpo: superfícies reversíveis e marcas de resistências no brinquedo de miriti
Authors: Seixas Ribeiro Joyce Otânia , De Brício Vilma Nonato
Published: August 2020

O objetivo é refletir sobre as representações do corpo nas imagens do brinquedo de miriti, um bem cultural da cidade de Abaetetuba/Pará. Neste sentido, buscamos apoio no Estudos Culturais pós-críticos, contando, entre outros, com Hall (2016), Kellner (1995), Foucault (1987) e Silva (1999). A decisão metodológica é pelo alfabetismo crítico, um procedimento emergente para a análise de imagens. Ao ser intensamente disseminada em blogs, livros, camisetas e bolsas, as imagens da peça casal de namorados representam o corpo e o casal ideal e afetam a todos, particularmente jovens do ensino médio. Por constituir não apenas a cultura contemporânea, mas as subjetividades juvenis no cotidiano escolar, as imagens merecem a atenção, pois mesmo representando corpos, gêneros e sexualidades hegemônicas, sendo a representação reversível, é capaz de constituir outros modos de ser e de viver.
Quem nasce em Bacurau é gente? Gênero e precariedade de vida no filme “Bacurau”
Authors: Bastos Felipe , Gonçalves Eduardo
Published: August 2020

Este artigo toma o filme “Bacurau” como objeto de reflexão para debater o conceito de sujeito a partir de duas noções de Judith Butler: a performatividade de gênero, a partir do personagem Lunga, e a distribuição desigual de condições precárias de vida, através das relações de reconhecimento entre moradores e estrangeiros do povoado fictício. Tomamos a narrativa cinematográfica como um documento cultural que, em uma perspectiva pedagógica, nos ensina e problematiza sujeitos, enquadramentos e identidades.
Encontros com o cinema de animação e com crianças na produção de filmes sobre direitos humanos
Authors: Filha Constantina Xavier
Published: August 2020

O artigo faz parte de pesquisa mais ampla realizada no estágio de pós-doutorado na Pós-Graduação em Educação da Unirio (2019-2020). Tem por propósito descrever o conceito de encontros com o cinema de Bergala (2008), traçar parte de minha trajetória como pesquisadora até os encontros com as crianças, nas experiências de produção de filmes de animação, em projeto de pesquisa e de extensão. Os filmes produzidos, doze, ao total, feitos com estudantes do 3º ao 5º ano do ensino fundamental, têm como temas-argumentos: infâncias; gênero; direitos humanos; violência contra crianças; fazer cinema; corpo/autocuidado/autoproteção. Todos os temas têm relação direta com a defesa dos direitos humanos das crianças. Ao discutir sobre eles, recorro a alguns dos filmes produzidos, assim como a informações de pesquisas realizadas com as crianças, para saber como elas pensam sobre este e outros temas, como dignidade humana, direitos e deveres, redes de proteção.
Anti-biofilm property of essential oils from Cymbopogon sp. against pathogenic bacteria in single-culture and co-culture
Authors: Millezi Alessandra Farias , Schuh Vanessa , Schuh Janaina , Amaral Taciara Penno do
Published: August 2020

In this study, we evaluated whether the essential oils (EOs) from Cymbopogon flexuosus and Cymbopogon martinii can prevent production of biofilms either in single or combined culture of Staphylococcus aureus and Pseudomonas aeruginosa. Biofilm formation was assessed by microtiter-plate test with further quantification of viable cells and biofilm biomass. The evaluated EOs at 0.78 % significantly (P 0.05) reduced only the viable cells of S. aureus that inhabited biofilm. However, in single-and co-culture assays, both oils significantly (P 0.05) decreased the amount of biofilm biomass. Biofilm reductions between 52-83% and 60-93% were achieved for the treatments with EOs from C. flexuosus and C. martinii, respectively. Although the biomass reductions of simgle and co-cultivated biofilms were significant, the same was not true for viable cells, except for S. aureus. Considering that the remaining colony forming units can reconstitute the EPS matrix, studies with higher concentrations than those used in this research are suggested in order to obtain greater logarithmic reductions of viable bacterial cells.
Optimization of production and partial characterization of xylanase from a newly isolated Bacillus amyloliquefaciens
Authors: Chaves Bruno Las-Casas , Martinazzo Ana Paula , Coca Brisabella , De Souza Adriane Nunes , Teodoro Carlos Eduardo
Published: August 2020

This paper reports the process of production optimization and partial characterization of xylanase from a newly isolated Bacillus amyloliquefacies VR002, isolated from local soil. The microorganism exhibited maximum xylanase production when 1.0% (v/v) of inoculum size was added to culture medium with initial pH 6, 1.0% (w/v) birchwood xylan, at 35 °C after 48h of incubation. Xylanase production in different carbon sources apart from birchwood xylan and xylose did not show high production levels. Optimum pH for xylanase activity was 6.0. The enzyme was alkali-stable and retained 100% of residual activity over the pH range from 6.0 to 10.0 for 24 h at 25°C. Optimum temperature for enzyme activity was 55°C. Xylanase was 100% stable at 4°C and 25°C even after 24h of incubation, a desirable characteristic for enzyme storage. Moreover, best crude extract volume and time reaction were found to be 10 µL and 5 min, respectively. After optimization of production and activity parameters, an increase of nearly 60-fold in xylanase activity (44.12 ± 4.36 U/mL) was achieved. Characteristics of B. amyloliquefaciens VR002 xylanase are particularly desirable for biotechnological applications
A cinematografia no ensino de filosofia
Authors: Machado Marcos
Published: August 2020

O propósito desse artigo é sugerir algumas pistas para explorar, no âmbito do ensino de filosofia, a dimensão de longas-metragens, sobretudo os que expõem conteúdo de caráter filosófico. Além disso, esperamos evitar algumas práticas que limitam a sua potencialidade, principalmente quando apenas são transpostos de modo didático as ideias, as situações ou os conceitos presentes em determinado filme como artifício atenuador da complexa relação ensino-aprendizagem ou, ainda, quando a obra cinematográfica é utilizada como um dispositivo que busca tão somente sensibilizar os estudantes para o assunto abordado em certo texto filosófico. Trata-se, então, de seguir os passos de alguns filósofos que analisaram a arte de reproduzir imagem em movimento e que insinuaram que determinada linguagem e estética cinematográfica possui aspecto filosófico, a saber: Theodor Adorno e Max Horkheimer (1985); Walter Benjamin (1987); Gilles Deleuze (1985); Jacques Rancière (2012); João Maria Mendes (2013); Julio Cabrera (2006).
Coat of arms and the flag of municipality Kosovska Mitrovica
Authors: Obradović Filip
Published: August 2020

Heraldic is the auxiliary science of history that deals with the research of coat of arms and vexillology is the science that emerged from heraldic and deals with the study of flags. The first town coats of arms in the South-Slavic area appeared in 13th century and some much later. Kosovska Mitrovica is a city in the North of Kosovo and Metohija in the Republic of Serbia and it got its first real coat of arms-emblem after World War Two. The municipal authorities announced the competition for the new coat of arms that was published in "Vecernje Novosti" in 2011. Nine works participated in the competition. The five-member panel that was supposed to chose the ideal solution suggested the municipal authorities to annul the competition since no option was appropriate for them. The municipal authority annulled the competition but they noticed the its mistake soon and corrected it very quickly after that. In that way municipality Kosovska Mitrovica got its coat of arms and a flag as well. The coat of arms of Kosovska Mitrovica municipality fully reflects its historical, cultural, religious, geographic and economic features but also the natural elements of the Kosovska Mitrovica municipality with its distinctive features. The coat of arms exists in three forms: small, medium and large depending of municipality's need and in accordance with the unwritten heraldic practice regarding the use of coat of arms of cities and municipalities in the Republic of Serbia. The municipal flag is represented on the large coat of arms of the municipality but it is also used as a separate symbol of the municipality.
Priority Rankings of Patient-Reported Outcomes for Pancreatic Ductal Adenocarcinoma: A Comparison of Patient and Physician Perspectives
Authors: Guan Michelle , Gresham Gillian , Shinde Arvind , Lapite Isaac , Gong Jun , Placencio-Hickok Veronica R. , Forrest Christopher B. , Hendifar Andrew E.
Published: August 2020

Background: Pancreatic ductal adenocarcinoma (PDAC) is associated with high symptom burden. However, treatment decisions currently depend heavily on physician interpretation of clinical parameters and may not consider patients’ health preferences. The NIH Patient-Reported Outcomes Measurement Information System (PROMIS) initiative standardized a set of patient-reported outcomes for use in chronic diseases. This study identifies preference rankings among patients with PDAC and physicians for PROMIS domains and compares the priorities of patients and their providers. Methods: We condensed the 96 NIH PROMIS adult domains into 31 domains and created a Maximum Difference Scaling questionnaire. Domain preference scores were generated from the responses of patients with PDAC and physicians, which were compared using Maximum Difference Scaling software across demographic and clinical variables. Results: Participants included 135 patients with PDAC (53% male; median age, 68 years) and 54 physicians (76% male; median years of experience, 10). Patients selected physical functioning (PF) as their top priority, whereas physicians identified pain as most important. PF, ability to perform activities of daily living, and symptom management were within the top 5 domains for both patients and physicians, and varied only slightly across age, sex, and ethnicity. However, several domains were ranked significantly higher by patients than by physicians, including but not limited to PF; ability to do things for yourself, family, and friends; ability to interact with others to obtain help; and sleep quality. Physicians ranked pain, anxiety, and depression higher than patients did. Conclusions: Our findings suggest that patients with PDAC value PF and engaging in daily and social activities the most, whereas physicians prioritize symptoms such as pain. Patient-reported outcomes need to become more integrated into PDAC care and research to better identify unmet patient needs, inform treatment decisions, and develop therapies that address outcomes valued by patients.
Cross-Sectional Analysis of the Associations Between Four Common Cancers and Disability
Authors: Iezzoni Lisa I. , Rao Sowmya R. , Agaronnik Nicole D. , El-Jawahri Areej
Published: August 2020

Background: Approximately 61 million Americans have a disability. Little research has explored whether disability is associated with subsequent diagnosis of cancer, the second-leading cause of death in the United States. The objective of this study was to explore associations between cancer and disability, focusing on 4 cancers that may present with nonspecific symptoms that could be conflated with aspects of disability, thus delaying cancer diagnoses. An analysis of a nationally representative survey using sampling weights to produce national estimates was performed. Methods: Civilian, noninstitutionalized US residents responding to the 2010–2017 National Health Interview Surveys totaling 259,392 Sample Adult Core survey respondents were included. We used self-reported functional status limitations to identify persons with movement difficulties (MD), complex activity limitations (CAL), and no disability. Multivariable regressions predicting cancer diagnosis included sociodemographic characteristics, tobacco use, body mass index, access to care indicators, and disability status. Results: Persons with preexisting disability had significantly higher rates of cancer (ranging from 0.40 [SE, 0.05] for ovarian to 3.38 [0.14] for prostate) than did those without disability (0.20 [0.02] and 1.26 [0.04] for the same cancers; all P<.0001). Multivariable analyses found strong associations of preexisting MD and CAL with colorectal cancer, with adjusted odds ratios (aORs) of 1.5 (95% CI, 1.2–1.9) and 1.9 (1.5–2.4), respectively. For non-Hodgkin’s lymphoma, the aOR for CAL was 1.5 (1.1–2.1). For prostate cancer, aORs for MD were 1.2 (1.0–1.3) and 1.1 (1.0–1.3) for CAL. Using cross-sectional survey data, we could only identify statistical associations, not causality. Conclusions: Our population-based analyses suggest that persons with disability may constitute a high-risk population, with higher cancer incidence. Optimizing appropriate screening and fully investigating new signs and symptoms are therefore critical for patients with disability.
Before and After The Network
Authors: Andersen Christian Ulrik , Cox Geoff
Published: August 2020

How do we think about networks under post- digital conditions? What does this imply for research? 

This journal issue takes as its outset, the call of the transmediale festival to “[leave] be- hind a decade marked by a backlash against the Internet and the network society” in order to re-evaluate the limits of ‘networks’. It refers to Robert Filliou’s “The Eternal Network,” an idealistic notion from the 1960s, pointing to the interconnectedness of everyday-life actions across an emerging global world at that time. This is a good reminder that network cultures exist beyond the technical reality of network culture as we now know it despite our primary identification of networks with social media and planetary computation. By drawing on the legacies of critical and autonomous network cultures, the aim was to make the limits of Internet-based networks visible but also highlight alternatives. Is there a conceivable counter-power to networks? Which alternative technological models and cultural narratives are needed to construct the principles of end-to-end communication anew? How might the critique of networks extend to non-western contexts and reflect the limits in a global perspective?

To answer such complex questions, this editorial begins by reflecting on the periodizing logic that invites us to leave behind “the backlash against the Internet.” What comes before and after the network?
Tagging Aesthetics
Authors: Bozzi Nicola
Published: August 2020

Social media have given social movements unprecedented tools for self-representation, however emancipatory identity politics are drowned out by the white noise of neoliberal self-branding practices. In response to this highly- aestheticised, de-politicised environment, we need a cultural re-negotiation of online categorisation. Rather than focusing on networks, this essay frames tagging as an everyday gesture of social media users that participates in the collective performance of identity. I argue this performance gives way to the materialisation of 'cultural avatars' – collective identity figures that lie beyond coherent representation and can reinforce reductive social stereotypes or inspire politically critical figurations. Apart from offering a cultural critique of tagging itself, the essay discusses a range of creative approaches to tagging that de-naturalise processes of online categorisation by drawing critical attention towards them.
Introduktion
Authors: K&K Redaktionen
Published: August 2020

Introduktion til oversættelse af Amy Riddle: ”Petrofiktion og politisk økonomi i den sene fossile kapitals tidsalder”
“Die Buchwelt zu Gast in Frankfurt”1
Authors: Norrick-Rühl Corinna
Published: August 2020

Since 1976, Frankfurt Book Fair (FBF) management has pinpointed a focus theme for
the fair, starting out with a focus on Latin America. From 1988 onwards, FBF has annually
invited one country/region to present itself and its authors, literature and culture at the
fair as “Guest of Honour.” This paper will discuss the effects of the Guest of Honour
presentation, using as its basis a dataset that compares number of fiction translations into
German from the source languages of the Guests of Honour. Overall, the contribution
will consider the way the Guest of Honour status shapes the literary field in Germany in the
year of the presentation and in the years following the presentation. It is also meant as an
impulse for further research on the Guest of Honour presentations at FBF.
Negotiating Value
Authors: Lenemark Christian
Published: August 2020

The Gothenburg Book Fair is one of the most important cultural events in Scandinavia today. Since 1985, it has grown into a meeting place for book lovers, librarians, and people in the book industry. However, it has also been surrounded by scandals and controversies. Inspired by Brian Moeran’s notion of the book fair as “a tournament of values,” and Barbara Herrnstein Smith’s constructivist approach to value, this article analyzes the Gothenburg Book Fair as an arena for negotiating value. The article first discusses how the value of the Gothenburg Book Fair has been under constant negotiation since its inception, and then examines how different actors participated in consolidating the fair’s value and function at the beginning of the 2010s. Finally, it considers the intensive debate about the Gothenburg Book Fair in 2016–2017, due to the decision to allow the extreme-right newspaperNya Tiderto have a stand in the exhibition halls, which above all resulted in a renegotiation of the book fair’s social and economic value. Through this diachronic and historical perspective, the article shows how a more pronounced theoretical value perspective in relation to book fairs and literary festivals provides new knowledge about these types of literary events and their role in literary culture as a whole.
Jaipur Literature Festival, the Gendered Literary Field, and the MeToo Movement in India
Authors: Das Arpita
Published: August 2020

As the literary field in India begins to become more complex, layered and diverse in terms of its gender representation despite the stubborn persistence of many aspects of its “tradition” male bastion character, the most celebrated and successful literary festival in the country emerges as a microcosmic manifestation of this tussle for power. Based on an autoethnographic account of the literary festival over eight editions and a close narrative of the sessions in its 2018 and 2019 editions along with a look at how these editions were reported in the media, and placing them within the frame of scholarship researching literary festivals as representations or fragments of “public culture”, this article looks at gender representation at the Jaipur Literature Festival in the immediate aftermath of the two waves of the MeToo Movement in India.
Cultural Capital as Performance
Authors: Dane Alexandra
Published: August 2020

The canvas tote bag, often branded with the name and logo of a popular cultural
institution or bookstore, has become a shorthand for an individual’s accumulated cultural
capital; this seemingly innocuous accessory has the power to signal to one’s peers the level
of their engagement with the cultural and creative industries in a seemingly casual but
deeply coded manner. The literary festival presents the perfect opportunity for individuals
to signal to those around them that they, for example, subscribe to the New Yorker
or donate money to the V&A museum. This article presents the findings of an
observational study conducted at four literary festivals in Australia, the United Kingdom
and the United States. Four distinct categories emerged from this analysis of tote bags
carried at literary festivals: the festival tote that is sold at the festival; totes
associated with cultural institutions; totes with political, satirical or ironic slogans;
totes that are not associated with any particular arts or cultural brand or institution. I
argue that, especially where the first three categories are concerned, the tote bags carried
at literary festivals are consciously chosen for the purpose of signalling one’s cultural
capital.
Shifting Interiority: Changing Encounters With Our Environment
Authors: Atmodiwirjo Paramita , Yatmo Yandi Andri
Published: August 2020

During COVID-19 pandemic, the whole world has witnessed and experienced dramatic changes in all aspects of life. As we adapt our everyday lives to restrictions and limitations to fight the pandemic, it also has become a trigger for us to rethink and re-position knowledge on spatial design disciplines. This Interiority issue compiles contributions that respond to a special call for papers that address these questions: How does the pandemic, including its impacts from lockdowns and physical distancing, affect how we think about interior and architecture? What lessons can we learn from this situation that we can use in future interior and architectural spaces and practices? How does the idea of interiority shift in this challenging situation?
The Charms of an American Queen Anne: Rediscovered a-lá COVID-19
Authors: De Celis David T.
Published: August 2020

This moment, the 2020 COVID-19 pandemic, has provided an opportunity—sometimes forced via crisis, or via moments of quiet reflection—to consider the inside, interior time and space, in new ways. In America, like other countries, architectural styles have come to us from foreign lands. Numerous domestic structures were influenced by British events from the 1700s–1800s. These styles—these architectures—were transformed by local/regional/national influences and events—events like this current international pandemic—that push the proverbial pause button, and cause us to re-think design. The author, who now resides and works (along with his family) in an 1886 Queen Anne style home, contemplates the various attributes and transformations of domestic architectures and the influences that shape them over time, asking: Why Queen Anne in America? How was it Victorian? And why is it relevant today? Empirical methods include observations and precedents-analysis, design work, the study of technological advances and interior-architecture history of the Victorian era. Emphasis on domesticity acknowledges both past and present by recognizing the importance of domestic architecture from the late 1700s through the 1800s, and into the present. Thus, we better understand how/why the Queen Anne style became ubiquitous in New England, and how its attributes of innate flexibility may help us today.
Slumber in a cell: honeycomb used by honey bees for food, brood, heating… and sleeping
Authors: Klein Barrett A. , Busby M. Kathryn
Published: August 2020

Sleep appears to play an important role in the lives of honey bees, but to understand how and why, it is essential to accurately identify sleep, and to know when and where it occurs. Viewing normally obscured honey bees in their nests would be necessary to calculate the total quantity and quality of sleep and sleep’s relevance to the health and dynamics of a honey bee and its colony. Western honey bees (Apis mellifera) spend much of their time inside cells, and are visible only by the tips of their abdomens when viewed through the walls of an observation hive, or on frames pulled from a typical beehive. Prior studies have suggested that honey bees spend some of their time inside cells resting or sleeping, with ventilatory movements of the abdomen serving as a telltale sign distinguishing sleep from other behaviors. Bouts of abdominal pulses broken by extended pauses (discontinuous ventilation) in an otherwise relatively immobile bee appears to indicate sleep. Can viewing the tips of abdomens consistently and predictably indicate what is happening with the rest of a bee’s body when inserted deep inside a honeycomb cell? To distinguish a sleeping bee from a bee maintaining cells, eating, or heating developing brood, we used a miniature observation hive with slices of honeycomb turned in cross-section, and filmed the exposed cells with an infrared-sensitive video camera and a thermal camera. Thermal imaging helped us identify heating bees, but simply observing ventilatory movements, as well as larger motions of the posterior tip of a bee’s abdomen was sufficient to noninvasively and predictably distinguish heating and sleeping inside comb cells. Neither behavior is associated with large motions of the abdomen, but heating demands continuous (vs. discontinuous) ventilatory pulsing. Among the four behaviors observed inside cells, sleeping constituted 16.9% of observations. Accuracy of identifying sleep when restricted to viewing only the tip of an abdomen was 86.6%, and heating was 73.0%. Monitoring abdominal movements of honey bees offers anyone with a view of honeycomb the ability to more fully monitor when and where behaviors of interest are exhibited in a bustling nest.
Empreendedorismo e secretariado executivo: uma proposição de reflexões críticas e de ações a partir de alunos estagiários e de organizações concedentes de estágios na área
Authors: Marçal Maria Christianni Coutinho , Barbosa Jessica Melo
Published: August 2020

A pesquisa propõe explorar como o empreendedorismo constitui-se na formação do futuro secretário executivo a partir de alunos estagiários e dos seus supervisores de campo. Os conteúdos presentes no discurso empreendedor vêm se significando na área de secretariado executivo com o sentido de ampliar o perfil profissional do secretário, reposicionando-o como um profissional mais estratégico do que operacional na organização, entre outros aspectos que o artigo investigou. A pesquisa justifica-se devido às lacunas existentes entre a proposição teórica referente ao tema constante na formação acadêmica e a práxis relatada pelos estagiários no campo empírico em orientações de estágio. Diante disso, o pressuposto que embasa este artigo é o de que há a necessidade de se refletir criticamente a competência empreendedora na formação do futuro profissional de secretariado. Em termos metodológicos, trata-se de uma pesquisa qualitativa de cunho interpretativista que, ao final, propõe ações de intervenção para  ampliar os sentidos do termo tanto na teoria quanto na prática. O corpus foi construído através de normatizações legais, literatura da área e entrevistas semiestruturadas com supervisores de campo de estágio e estagiários. Como resultado, obteve-se, entre outros aspectos, que os sentidos atribuídos à relevância do empreendedorismo na formação profissional foram convergentes tanto na literatura quanto no mercado e também no discurso do futuro profissional. Entretanto, na prática, os estagiários não perceberam as organizações concedentes de estágio como ambientes incentivadores na formação dessa competência.
Mapas cognitivos de identidade da experiência de declínio organizacional
Authors: De Vasconcelos Eveli Freire , Bastos Antonio Virgilio Bittencourt , Casali Maria Eduarda Avancini
Published: August 2020

O texto a seguir, elege como foco de interesse central o mapeamento dos elementos constituintes do esquema cognitivo de trabalhadores sobre o fenômeno de declínio organizacional vivido em um projeto organizacional de grande porte. A área teórica deste estudo delineou-se pela Ciência Cognitiva, apresentando como conceito operacional principal a teoria do esquema cognitivo, permitindo, assim, discutir as estruturas de conhecimento dos trabalhadores em relação a um elemento de sua realidade. Dessa forma, explorar por meio de entrevista, realizar a análise de conteúdo e descrever a maneira como esses sujeitos concebem e explicam a experiência de declínio organizacional é o que nos remete à investigação da complexidade que pode existir entre as perspectivas individuais e grupais, interfaceadas pela perspectiva organizacional. Os relatos revelam que o insucesso (declínio) do projeto organizacional vai além da dimensão financeira e integra questões políticas, sociais e morais, relacionando o fenômeno predominantemente aos fatores macroambientais. Foi possível, identificar que os esquemas explorados se mostraram úteis para a compreensão do significado da experiência em uma organização que entrou em declínio A título de conclusão, permite-se pensar o trabalhador em tempos de crise, a possibilidade de observação de diferentes articulações contextuais, que podem fortalecer ou fragilizar a saúde psicossocial dos atores e das organizações de trabalho especialmente frente à real ameaça de desemprego presente durante a ocorrência de declínio.
Status, Prospects and Market Potentials of the Sea Cucumber Fisheries with Special Reference on Their Proper Utilization and Trade
Authors: Rahman M. Aminur , Chowdhury Saddam Hossain , Hasan Md. Jahidul , Rahman Md. Habibur , Yeasmin Syeda Maksuda , Farjana Nawshin , Molla Md. Habibur Rahman , Parvez Md. Shamim
Published: August 2020

Sea cucumbers belonging to the phylum Echinodermata are important marine invertebrates, generally occur in the sandy substrates and rocky shores near the bottom of sea. This review work has been attempted to make an interlink between biological and socio-economical perspectives of sea cucumber because of the high demand in the present world. The outer body part of sea cucumber (bêche-de-mer) has been recognized for producing secondary metabolites including vitamins and triterpenoid glycoside saponins that have profound ecological and bio-medicinal significance. Sea cucumbers are also used to remove arthritis pain, exert wound healing, and nowadays, are utilized in human health therapeutics and Asian folk medicine. Due to higher pharmaceutical, cosmeceutical and nutraceutical values, sea cucumber has become one of the most essential products, and fetched higher market prices and therefore, provide a significant earning source and employment opportunity to the coastal communities in many countries. The sea cucumber and its product have been considered to be the excellent bioresource in the invertebrate fishery, whose harvestings, transporting, handlings, processing and maintenance are easy, convenient and cost-effective. Historically, bêche-de-mer were harvested from the multi-species capture fishery and stored for long times for selling to the businessmen and traders directly on the site. As like other lucrative and expensive food items viz., fish-maws, shark-fins and abalones, sea cucumbers are taken into the account as the high-valued products in the world seafood markets. Nevertheless, bêche-de-mer product supply in the South-East Asian countries has been decreasing day by day because of unstrained harvesting and overexploitation. On the other hand, the marketing structure in these countries is typically ineffective and the trading networks are multifaceted. Due to the lack of proper information, fishermen are not usually getting proper values and actual prices from the sea cucumber products, whereas other distributors and value-chain members have made complex systems, which have led to high cost of the products. The sea cucumber products will still have higher possibility of trading throughout the world markets, that might eventually contribute to the global economy in a very worthwhile, significant and sustainable manner.
Genetic Divergence Studies for Gall Midge Incidence, Earliness, Yield and Yield Components in Rice (Oryza sativa L.) Genotypes in Telangana State
Authors: Siddi Sreedhar
Published: August 2020

The study was carried out with 32 genotypes of rice (Oryza sativa L.) under irrigated system in RBD design with three replications at Agricultural Research Station, Kunaram in Telangana State during the rainy season of 2017. In general, major problem is high incidence of gall midge (Biotype 3) in rainy season under early as well as late planting conditions in Northern Zone of Telangana State. Hence, all the 32 genotypes were evaluated with an aim to know the divergence among them for gall midge incidence, earliness, yield and yield components. Based on D2 analysis, 32 genotypes were distributed into twelve clusters with the cluster I (12) containing maximum number of genotypes followed by cluster II (9). Highest inter cluster distances were observed between the clusters X and XII (2469.5) followed by III and XII (2283.3), and VII and XII (2173.6) suggesting wide diversity between the traits. Cluster mean analysis revealed that genotype, WGL 1119 from the cluster V would be used in breeding programme to develop gall midge resistant, high yielding, early duration, non lodging, medium slender grain genotypes as it recorded very low incidence of galls (0.9%) with high yield (4869.7 kg/ha), early duration (84.7 days), short stature (93.7 cm) and less 1000-grain weight (14.8 g). The genotypes, KNM 2305 and MTU 1001 from the clusters viz., VIII and X, respectively were identified as potential lines for developing high yielding, early and medium duration, long bold or long slender grain varieties. Among the traits studied, days to 50% flowering (55.8%) and 1000-grain weight (31.9%) manifested highest contribution towards total divergence, thus, these traits could be given due importance by the breeders for development of superior rice genotypes under crop improvement programme.
Immunomodulatory Effects of Zinc as a Supportive Strategies for COVID-19
Authors: Tayyib Nahla A. , Ramaiah Pushpamala , Alsolami Fatmah J. , Alshmemri Mohammed S.
Published: August 2020

Coronaviruses 2019 (Covid-19) is a massive family of viruses that causes respiratory illnesses ranging from the common cold to the most severe conditions such as Middle East Respiratory Syndrome and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that represents the humanitarian crisis on a global scale. Currently, there are no therapeutic strategies approved by the U.S.Food and Drug Administration (FDA) to cure or prevent COVID-19. Global research efforts from around the world extrapolate the updates focusing specifically on the biphasic nature of Covid-19 that involve both innate and acquired immunity. Even though researchers around the globe are racing to invent a life-saving therapeutics and vaccines to tackle COVID-19, the only available venture is a supportive approach in rendering treatment to patients with severe and non-severe cases of COVID-19. Supplementation of several vitamins and trace elements showed the expected favorable impact on enhancing immunity in viral infection. Numerous studies prompted the value of zinc (Zn) supplementation that prevents the virus from entering cells by binding with protein in potentiating antiviral immunity, which is realized through different mechanisms, including the improvement in markers of immune function. Zinc is also an associated factor for several enzymes (needed for the activity for over 300 enzymes), transcription factors, and replication factors. Interestingly, low-level zinc results in dysfunction of all immune cells, subjects with altered zinc state have a high risk for infectious disorders, autoimmune disorders, and cancer. Several assumptions regarding immunomodulators of zinc remain unresolved. This review aimed to explore the hypothetical association of Zinc supplementation (the key immunomodulator) in association with a preventive and therapeutic role of treating patients with COVID-19.
The Relationship between Financial Distress and Financial Health Prediction Model: A Study in Public Manufacturing Companies Listed on Indonesia Stock Exchange (IDX)
Authors: Fachrudin Khaira Amalia
Published: August 2020

Financial distress prediction models of Altman, Springate, Zmijewski, Grover, and Khaira have been widely applied to predict financial distress and financial health. This study aims to analyze score correlations within the prediction results of the mentioned models applied in manufacture companies listed in the Indonesian Stock Exchange. The sample includes 30 companies which faced financial distress during economic crisis in 1997–1998 and, as comparison, incorporates 28 financially healthy companies. Observations were made during one and two years before the financial distress occurred, i.e. between 1995 until 1999, as well as from 2015 until 2018 to measure the financial health level in the companies. In this study, we use the correlation analysis. The results showed that  models which have a strong and significant relationship at alpha 5% are models from Altman - Springate, Altman - Khaira, Springate - Khaira, and Zmijewski - Khaira. Grover model which does not have the predictor in the form of leverage, however has a weak correlation with other model as well as the actual condition
Which Retail Firm Characteristics Impact On Financial Distress?
Authors: Heniwati Elok , Essen Erlina
Published: August 2020

This study is to examine whether liquidity, profitability, leverage, sales growth, operating capacity, and size have influenced on financial distress by using retail industry that listed in the Indonesia Capital Market. Sample determination basing on purposive sampling results 19 companies with complete data over the observation period (2014-2018). Data was manually collected from the website, www.idx.com. By using logistic regression, the findings show that profitability and leverage have significant influenced on financial distress. Moreover, predictor liquidity, sales growth, operating capacityand firm’s size have no relationship with financial distress.
Application of Ensemble Empirical Mode Decomposition based Support Vector Regression Model for Wind Power Prediction
Authors: Karijadi Irene , Mulyana Ig. Jaka
Published: August 2020

Improving accuracy of wind power prediction is important to maintain power system stability. However, wind power prediction is difficult due to randomness and high volatility characteristics. This study applies a hybrid algorithm that combines ensemble empirical mode decomposition (EEMD) and support vector regression (SVR) to develop a prediction model for wind power prediction. Ensemble empirical mode decomposition is employed to decompose original data into several Intrinsic Mode Functions (IMF). Finally, a prediction model using support vector regression is built for each IMF individually, and the prediction result of all IMFs is combined to obtain an aggregated output of wind power Numerical testing demonstrated that the proposed method can accurately predict the wind power in Belgian.
Ergo-Biopsychosocial Approach to Support the Quality of Life of Small Housing Inhabitants
Authors: Hartono Markus , Tjahjoanggoro Antonius Johanes , Tondok Marselius Sampe , Hapsari Indri
Published: August 2020

A study on the intervention of human factors engineering (known as ergonomics) on sustainable living based on biopsychological needs was conducted, taking samples of small housing inhabitants. In total, 90 participants were involved. Those who were living in small housings have a significant challenge of how to live comfortably given very limited space. The measurement of the quality of human life through WHOQOL-BREF (World Health Organization Quality of Life-BREF) and ergonomics-based usability were used to describe the current human well-being satisfaction, to propose the modified physical facilities, and to validate the proposed design and improvement. The findings showed that all implemented improvements have supported the inhabitant’s quality of life.
Familial Wilms' Tumor with Neural Elements: Characterization by Histology, Immunohistochemistry, and Genetic Analysis
Authors: Hussong Jerry W. , Perkins Sherrie L. , Huff Vicki , McDonald J. Matthew , Pysher Theodore J. , Beckwith J. Bruce , Coffin Cheryl M.
Published: July 2002

Wilms' tumor (WT) is the most common renal malignancy of children. While most occur sporadically, a small percentage are familial or occur as part of a developmental syndrome. Classic WTs exhibit a triphasic histologic pattern composed of blastema, epithelium, and stroma. Occasionally, heterologous elements may also be observed. In this study we investigated a series of four WTs that occurred within a single familial aggregate and contained focal areas of neural differentiation. The tumors were evaluated histologically for the presence of neural elements and immunohistochemically for expression of neural-related markers. Genetic linkage analysis was performed on 3 of the 4 WTs. In addition to the classic triphasic histology, the WTs contained tumor rosettes (4/4), ganglion cells (2/4), foci of ganglioneuromatous differentiation (2/4), and anaplasia (1/4). Staining for chromogranin, S-100, synaptophysin, vimentin, and neuron-specific enolase was positive in all 4 tumors within the areas of neural differentiation whereas staining for CD99 (013) and glial fibrillary acidic protein was negative. Linkage analysis studies suggest that the familial predisposition gene segregating in this family is at 19q13.4. To our knowledge, this is the first reported series of WTs with neural differentiation that occurred within a single family aggregate. Genetic linkage analysis of this family is consistent with linkage to the FWT2 WT predisposition gene at 19q13.4. We propose that these tumors may represent a unique manifestation of tumor susceptibility in this family.
Gonadal Pathology in Triploidy
Authors: McFadden Deborah E. , Pantzar J. Tapio , Jevon Gareth P.
Published: July 2002

There are numerous reports describing the pathology of the fetus and placenta in triploidy. Although gonadal pathology is described in many of these reports, consistent changes have not been noted nor is it clear whether genital ambiguity can be considered part of the triploid phenotype. We present a case of triploidy of probable diandric origin, in which there were dysgenetic gonads with abnormal seminiferous tubules, nodules of undifferentiated stroma, and focal absence of the tunica albuginea. As this finding was distinctly unusual in our experience of triploid gonadal pathology, we reviewed the gonadal histology in 51 fetal and infant triploids examined in our autopsy/embryopathology laboratory. The gonads were compared to age-matched normal controls to determine if there was a specific gonadal pathology associated with triploidy and if there was any correlation of this pathology with parental origin of the triploidy. Our review of the triploid gonads indicated that while minor, nonspecific changes were not uncommon, overtly dysgenetic gonads, as observed in the index case, are rare.
Sacral Chordoma in Early Childhood: Clinicopathological and Immunohistochemical Study
Authors: Iwasa Yoko , Nakashima Yasuaki , Okajima Hideaki , Morishita Shinobu
Published: July 2002

Two cases of sacral chordoma in a 7-year, 9-month-old boy and a 3-year, 4-month-old boy are presented. In addition to the typical histology of conventional chordoma, both tumors showed the less differentiated sarcomatoid appearance of atypical chordoma in the major portion. Immunohistochemically, in both cases neoplastic cells in areas of conventional as well as atypical chordoma were positive for keratins (CAM 5.2, AE1 and AE3), epithelial membrane antigen, vimentin, S-100 protein, carcinoembryonic antigen, and glial fibrillary acidic protein. Both patients underwent resection of the tumor and chemotherapy. In comparison with conventional chordomas in adults, however, these two tumors showed more aggressive clinical course and were less amenable to therapeutic control. The older boy died of multiple metastasis 1 year after initial diagnosis. At the last follow-up, 15 months after initial diagnosis, the younger boy was alive, but with recurrent and metastatic disease of the left parasacral area and chest wall. Our studies of these two cases and the reported cases suggest that sacral chordoma in children has distinctive clinico-pathologic features denoting a highly aggressive tumor and that it should be treated as such.
Endocardial Fibroelastosis in L-Transposition of the Great Arteries with Ebstein's Anomaly: Revisited
Authors: Dahdah Nagib S. , van Doesburg Nicolaas H. , Russo Pierre
Published: July 2002

Ebstein's anomaly is a congenital deformity of the tricus-pid valve consisting mainly of leaflet malinsertion. Clinical presentation varies from asymptomatic patients to those with congestive heart failure secondary to significant valvular regurgitation and low right ventricular output. We report here the case of an infant with a diagnosis of corrected transposition of the great arteries and Ebstein's deformity of the left-sided tricuspid valve who developed pulmonary hypertension and endocardial fibroelastosis, two unusual associations with this lesion. We also discuss the pathophysiology of this association and related literature.
Neonatal Hemochromatosis, Renal Tubular Dysgenesis, and Hypocalvaria in a Neonate
Authors: Johal Jasbir S. , Thorp James W. , Oyer Calvin E.
Published: July 2002

We report a neonate with neonatal hemochromatosis (NH), renal tubular dysgenesis (RTD), and hypocalvaria. NH is a fatal condition of the newborn, characterized by severe idiopathic liver failure of intrauterine onset and siderosis, intra- and extrahepatic, with sparing of the reticuloendothelial system. RTD is characterized by short, abnormally developed cortical tubules that lack proximal tubule differentiation. Although both NH and RTD have been reported as entities with a genetic component, similar findings can be secondary to in utero insults. Hypocalvaria has been reported in association with fetal hypoxia including that secondary to angiotensin converting enzyme inhibitors. This 38-week-old infant died at 8.5 h. The small nodular liver weighed 44 g. Grossly, the kidneys were normal. Hypocalvaria was present. Microscopically, the hepatic parenchyma was distorted by fibrous tracts, proliferation of bile ducts, and abundant iron deposition in hepatocytes. Extrahepatic siderosis in the pancreas, myocardium, and other organs was consistent with NH. Proximal convoluted tubules were not seen on routine stains and markers for proximal tubules were negative. Previous reports have linked NH with RTD and RTD with hypocalvaria. This infant had all three of these rare conditions, which have been hypothesized or shown to be due to genetic factors, hypoxia, or drugs. The etiology in this case is unknown.
Practical Approach to Processing Osteosarcomas in the Surgical Pathology Laboratory
Authors: Wold Lester E.
Published: July 2002

The pathologic assessment of definitive surgical specimens in patients treated for osteosarcoma can be rapidly accomplished using a few pieces of special equipment. Rapid decalcification with formic acid–formalin and routine tissue processing allow the histology laboratory to rapidly prepare histologic slides for pathologic evaluation. A simple qualitative assessment of tumor response to chemotherapy allows the pathologist to classify the tumor response rapidly and reproducibly, and a simple report format allows for unambiguous communication with the patient and physician.
X-Linked Lymphoproliferative Disease: Pathology and Diagnosis
Authors: Maia Diane M. , Garwacki Christopher P.
Published: July 2002

X-linked lymphoproliferative disease (XLP) is a rare familial disorder resulting in selective immunodeficiency to the Epstein-Barr virus (EBV), characterized by uncontrolled proliferation of EBV-infected lymphocytes. Phenotypes of this disease are variable and include fulminant infectious mononucleosis, hypogammaglobulinemia, and malignant lymphoma. In this article, we describe a case of a previously healthy 4-year-old boy with serologic evidence of acute EBV infection who died of fulminant hepatic failure. Histopathological examination of tissue obtained postmortem showed hemophagocytosis and prominent polymorphous infiltrates associated with necrosis in the liver, spleen, and lymph nodes. Semiquantitative polymerase chain reaction (PCR) utilizing primers complementary to the EBV gene LMP2a performed on samples of liver tissue demonstrated approximately 0.6 copies of the EBV gene per cell. Immunohistochemistry demonstrated light chain restriction and PCR studies of the immunoglobulin V-D-J region revealed two strong bands, consistent with a clonal B cell proliferation. Extended family history revealed that the boy's family was followed by the XLP Registry, which was established in 1978 to follow kindreds with XLP. The genetic abnormality associated with XLP has been localized to the Xq25, allowing RFLP analysis to identify female carriers and affected boys.