bluuebunny/crossref_metadata_2025 huggingface dataset:
Lipase-mediated selective hydrolysis of lipid droplets in phase separated-liposomes
Authors: Papadopoulou Panagiota , van der Pol Rianne , van Hilten Niek , Moradi Mohammad-Amin , Ferraz Maria , aerts Johannes , Risselada Jelger , sevink agur , kros alexander
Published: January 2023

The membrane-protein interface in lipid nanoparticles (LNPs) is important for their in vivo behavior. Better understanding may assist to evolve current drug delivery methods to more precise, cell- or tissue-specific nanomedicine. Previously, we demonstrated how phase separation can drive liposomes to cell specific accumulation in vivo, through the selective recognition of phase-separated liposomes by triacylglycerol lipases (TGLs). This exemplified how liposome morphology can determine the preferential interaction of nanoparticles with biologically relevant proteins. Here, we investigate in detail the lipase-induced morphological changes of phase separated liposomes - which bear a lipid droplet in their bilayer - and unravel how lipase recognizes and binds to the particles at a molecular level. We find that phase separated liposomes undergo selective lipolytic degradation of their lipid droplet while overall nanoparticle integrity remains intact. Next, we combined MD simulations and in vitro experiments to identify the Tryptophan-rich loop of the lipase – a region which is involved endogenously in lipoprotein binding – as the region through which the enzyme binds to the particle. We demonstrate that this preferential binding is due to the lipid packing defects induced on the membrane by phase separation. These findings are a significant example of selective LNP – protein communication and interaction, aspects that may further the control of the in vivo behavior of lipid nanoparticles.
Time-Resolved Electron Paramagnetic Resonance Spectrometer Based on Ultrawide Single-Sideband Phase-Sensitive Detection
Authors: Zhang Shixue , Zhou Shengqi , Jiao Lei , Guo Xingwei
Published: January 2023

A time-resolved electron paramagnetic resonance (TREPR) method with 40 ns time resolution and a high sensitivity suitable for the detection of short-lived radicals under thermal equilibrium is developed. The key is the introduction of a new detection technique named ultrawide single sideband phase sensitive detection (UWSSB-PSD) to the conventional continuous wave EPR, which remarkably enhanced the sensitivity for the detection of broadband transient signals compared with the direct detection protocol. By repeatedly triggering a transient kinetic event f(t) (e.g., by laser flash photolysis) under a 100 kHz magnetic field modulation with precise phase control, this technique can build an ultrawide single sideband modulated signal. After single sideband demodulation, the flicker noise-suppressed signal f(t) with an ultrawide bandwidth is recovered. An UWSSB-PSD TREPR spectrometer prototype has been built in our laboratory, which integrated timing sequence control, laser flash excitation, and data acquisition systems as well as the UWSSB-PSD algorithm with a conventional CW-EPR. It exhibited excellent performance in monitoring a model transient radical system, laser flash photolysis of benzophenone in isopropanol. Both the intense chemically induced dynamic electron polarization (CIDEP) signals and the much weaker thermal equilibrium EPR signals of the generated acetone ketyl radical and benzophenone ketyl radical were clearly observed within a wide timescale (ranging from sub-microsecond to milliseconds). This prototype validated the feasibility of the UWSSB-PSD technique and demonstrated its superior performance in studying complex photochemical systems containing various transient radicals, which complements the established TREPR techniques and provides a powerful tool for deep mechanistic understandings, such as in photoredox catalysis and artificial photosynthesis.
Flow-based approach for scalable fabrication of Ag nanostructured substrate as a platform for surface-enhanced Raman scattering
Authors: Kanike Chiranjeevi , Wu Hongyan , A.W. Zaibudeen , Li Yanan , Wei Zixiang , Unsworth Larry D. , Atta Arnab , Zhang Xuehua
Published: January 2023

The droplet-based biphasic reaction is an efficient strategy for the fabrication of surface-bound nanostructures. Here, we developed a process of fabricating ordered micro-ring arrays of silver (Ag) nanostructures from surface nanodroplet reaction on a micro-patterned hydrophobic substrate for reproducible detection by surface-enhanced Raman spectroscopy (SERS). Our process consisted of the generation of surface nanodroplet arrays, followed by a biphasic chemical reaction between droplets and the continuous flow of silver nitrate (AgNO3) precursor solution. The parameters in the formation and reaction of the droplet array were well controlled to maintain the uniformity of Ag nanostructures throughout the substrate. By scaling up the process parameters and the size of the microchamber, we were able to produce a SERS substrate with a surface area of > 60 cm^2 in a single run. Such a large area could be sufficient for analyzing more than a thousand samples. We demonstrated the repeatability of SERS measurements using Ag nanostructures by analyzing three environmental (rhodamine 6G, chlorpyrifos, triclosan), a biological (indoxyl sulfate), and a psychoactive drug (tetrahydrocannabinol) compounds. 2D mapping of SERS intensities was also performed for both small and large-scale substrates by collecting data from more than 100 locations on the substrate. Our work demonstrated droplet-based biphasic reaction as a simple approach for the fabrication of SERS substrate with a large area. The technique may help to eliminate the requirement for sophisticated equipment for the fabrication of SERS active substrate.
How beam damage can skew synchrotron operando studies of batteries
Authors: Jousseaume Thibaut , Colin Jean-François , Chandesris Marion , Lyonnard Sandrine , Tardif Samuel
Published: January 2023

With the advent of high brilliance 4th generation synchrotron sources, the issue of beam damage on the samples cannot be ignored and deserves a wide attention. It is especially true for operando studies in batteries, since the intense photon fluxes are commonly used to probe ever finer effects. Here we report on a quantitative study on the causes and consequences of synchrotron X-ray beam damage in batteries, based on the case study of operando X-ray diffraction. We show that beam damage is caused by the mingled action of dose and dose rate. The after-effects can lie in a broad range, from mild modifications of the crystalline structure to artificial phase transitions, and can thus impede or bias the understanding of the mechanisms at play. From our results, we estimate the doses at which the different effects appear, and provide recommendations for the design of operando synchrotron experiments.
Solar driven in-air plasma discharge for effective activation of water flow through self-suction mechanism
Authors: Gao Yawen , Shi Hongbo , Saedi Ziya , Zeng Binglin , Zhang Xuehua
Published: January 2023

Plasma activated water(PAW) is water that is treated with cold plasma discharge. The dissolved reactive oxygen and nitrogen species in PAW are desirable for wastewater treatment, environment remediation, food processing and storage, enhanced plant growth in agriculture and many other applications. In this work, we develop microbubble-enhanced PAW production through a self-suction mechanism. Microbubbles form under the strong turbulence effect at the throat of a cavitation tube, transferring active species into a stream of water. As demonstrated by degradation rate of sulfathiazole, a model antibiotic compound in water, the main parameters identified from our experiments to be essential for the activation efficiency are the design of the cavitation tube, the flow rate of the water stream, and the distance from the discharge to the flow. Our three-dimensional numerical simulations reveal the impact of the tube dimensions on the multiphase flow characteristics. The simplicity of self-suction mechanism allowed us to set up a solar-driven, stand-alone cold plasma system to generate PAW outdoor. The as-prepared PAW can boost the growth rate of bean and peanut sprouts in hydroponics about 80% and 66%, respectively. The portable PAW production may open the door to even broader applications of field activated water for applications in sustainable agriculture and in environment remediation.
Comparative Analyses of Data Driven Machine Learning Models for TADF Emitters
Authors: Bhattacharyya Kalishankar
Published: January 2023

Thermally activated delayed fluorescence (TADF) chromophores have attracted significant attention because they can harvest singlets and triplets in organic light-emitting diodes (OLEDs), resulting in high external quantum efficiency (EQE). This work aims to use a data-driven machine-learning model to predict the relationship between EQE and essential features of TADF-based OLEDs. The study uses a set of experimental data and applies various machine-learning models to analyze the relationship between EQE and the features of the device. The Random Forest model is found to have the highest accuracy for predicting EQE for non-doped TADF emitters. The importance of feature selection and its correlation with EQE is also analyzed, providing insight into how to select the best machine-learning model for rapid material screening and device optimization for non-doped TADF materials.
Métodos de comunicación industrial inteligente aplicado a un módulo didáctico de los laboratorios de docencia del ITM
Authors: Sepúlveda Balbin Juan Camilo , Botero Gómez Vanessa , Isaza Hurtado Jhon
Published: January 2023

Las comunicaciones industriales, a diferencia de los dispositivos y procesos que utilizamos diariamente, tienen requerimientos especiales para el almacenamiento y gestión de información. Aquí es donde toman relevancia los conceptos asociados al Internet Industrial de las Cosas (IIOT por sus siglas en ingles) y la computación en el borde. A nivel industrial se manipulan y controlan procesos donde es necesario asegurar la sincronía, evitar la pérdida de información y la latencia asociados a la comunicación, por esta razón, se utilizan controladores industriales tipo PLC o diferentes tipos de sistemas embebidos. Estos dispositivos de control además requieren de una Interfaz de Programación de Aplicaciones (API por sus siglas en ingles), que asumen el papel de puente para comunicarse con un servidor externo, ya sea local (borde) o en la nube. Este trabajo propone una taxonomía del hardware y software utilizado para llevar a cabo una conexión exitosa entre un controlador (puede ser un PLC o sistema embebido) y una base de datos alojada en la nube, finalmente la información es transmitida bidireccionalmente a través de una interfaz de usuario desplegada con una dirección IP pública. Además, en este trabajo se presenta un procedimiento de configuración y conexión genérico para la adquisición y alojamiento de datos en la nube, de acuerdo con los dispositivos y herramientas presentadas en la taxonomía propuesta. Finalmente, el procedimiento es aplicado a un módulo ubicado en el laboratorio de Automatización del Instituto Tecnológico Metropolitano de Medellín.
Grupo estudiantil de mujeres en ingeniería: un espacio para aprender, compartir y ayudar en comunidad
Authors: Hurtado Jairo , Cano Morales Martha Lucía , Rodríguez Mejía Eduardo
Published: January 2023

En algunas carreras de ingeniería la proporción de hombres y mujeres es bastante desbalanceada. En algunos casos este desbalance, que puede llegar a ser incluso superior de 10 a 1, puede generar en las estudiantes incomodidades, falta de empatía por parte de sus compañeros e incluso ser objeto de algún tipo de discriminación. La Comisión Internacional de Futuros de la Educación liderada por la UNESCO, ha hecho un llamado de esperanza para trabajar en la pluralidad de futuros posibles más justos y sostenibles para todos. En línea con este llamado, se desea promover desde las facultades de ingeniería, espacios de aprendizaje, visibilidad y promoción de las mujeres en el estudio de las ingenierías. Debido a la pandemia el grupo estudiantil de Mujeres en Ingeniería (WIE) se vio bastante afectado, dado que las personas que lo integraban empezaron prácticas profesionales o se graduaron y debido a la situación coyuntural de las clases remotas, no se promovió una adecuada renovación para así garantizar su continuidad. A partir de las experiencias y los aprendizajes obtenidos en el EIEI 2021, de la ponencia realizada en este mismo evento y de una encuesta realizada a más de 300 egresadas de la Facultad y estudiantes de último año, en la cual ellas nos compartieron, sus vivencias dentro de su pregrado y su vida laboral, así como sugerencias, recomendaciones y su completa disponibilidad de colaboración, se promovió el resurgimiento de este grupo estudiantil, el cual ha crecido y se ha fortalecido con estudiantes de todos los semestres, desde primero hasta último año, de más de cinco ingenierías y con el apoyo de profesores tanto de cátedra como de tiempo completo. En el documento se describirán los pasos seguidos para la reactivación del grupo, la agenda que se ha manejado, la colaboración con otras universidades, la colaboración de egresadas de la Facultad y egresadas de otras Facultades, la creación de identidad, fortalecimiento de la red, las tareas realizadas, las discusiones planteadas, el registro de las actividades, el desarrollo personal y empoderamiento que se ha tenido por parte de las integrantes y los resultados obtenidos hasta el momento. Finalmente se mostrará qué, aunque el grupo se llama Mujeres en Ingeniería y el nombre puede parecer excluyente, se tiene la participación y el interés de estudiantes y profesores hombres, de conocer, aprender y aportar en las temáticas manejadas al interior del grupo.
Enseñar ingeniería a quien no quiere ser ingeniero
Authors: Vivas Ricardo Jaime
Published: January 2023

¿Por qué razón alguien se sometería a la situación de enseñar algo que no es lo que quienes toman la clase quieren aprender? ¿Y si no se equivocaron de aula, por qué estarían ahí los estudiantes? Sucede a diario. Dichos estudiantes en general son conscientes de haberse matriculado en un programa universitario de pregrado en Ingeniería de Sistemas. No suelen llegar motivados por la forma en que la Ingeniería contribuye a la solución de diversos problemas de la sociedad, con fundamento en las matemáticas y las ciencias, y mediante un proceso riguroso mejorado a lo largo de ocho mil años. Más bien parecen seguros de saber ya lo suficiente; de tan solo necesitar que en su formación universitaria les entreguen en la mano nuevas sentencias de algún lenguaje de programación, quizás aprender algún lenguaje nuevo, o mejor, una herramienta en la que no haya que programar mucho, sino ensamblar y publicar en alguna app store. Haber conseguido buenos resultados en el curso o en alguna maratón de programación en el colegio, o tener experiencia en desarrollo de sitios web, son respaldo suficiente para sus expectativas y su nivel de confianza. Los problemas surgen muy pronto: apenas se introduce el método. La sorpresa viene por cuenta de que el término Ingeniería no es tan solo una muletilla, que durante poco más de cincuenta años ha estado acompañada del apellido de Sistemas, para denominar de forma elegante a lo que simple y llanamente es programación de computadores, de acuerdo con los supuestos de los novatos del programa. ¿Cómo así que las líneas de código no se inventan en simultaneidad con la manipulación del teclado, sino que obedecen a un análisis previo, a un diseño expresado en múltiples diagramas, a la selección de las técnicas y herramientas más convenientes para el proyecto? ¿Cómo es eso de que el resultado no solo debe funcionar a satisfacción del usuario, sino que además debe superar pruebas para asegurar el cumplimiento de estándares de calidad? Con esa sorpresa se encuentran los estudiantes, y con frecuencia es una fuente de frustración que dificulta el abordaje del rigor de la Ingeniería del Software, que es como la Association for Computer Machinery (ACM) y el Institute of Electric and Electronic Engineers (IEEE), los mayores referentes curriculares de talla mundial definen a una de las cinco disciplinas que conforman el campo de la computación, el mismo que con frecuencia se ve reducido a la programación, y que es una de las líneas de acción de la Ingeniería de Sistemas en Colombia. Esta ponencia muestra la experiencia de un programa de Ingeniería de Sistemas, soportada en investigación aplicada, discusión curricular y crítica de la interacción entre la academia y la industria. El proyecto busca formular métodos de enseñanza en Ingeniería de Sistemas que motiven a los estudiantes a superar sus expectativas iniciales y adherir a una visión más ambiciosa de su futura profesión sin desertar en el intento.
Evaluación del suministro de agua potable en las zonas rurales frente a la Resolución 844, caso Cogua – Cundinamarca
Authors: Ayala Rojas Luis Efrén
Published: January 2023

La presente investigación, tiene como fin evaluar el abastecimiento y saneamiento de agua en el municipio de Cogua en zonas rurales, recopilando diferentes fuentes de información, esto con el fin de dar una evaluación de municipio de Cogua a nivel rural. Además, se hará una revisión teórica con respecto a la resolución 844 que rige las zonas rurales de Colombia, para así determinar la situación en la que se encuentra el municipio frente al abastecimiento de agua potable de calidad. Sin embargo, se hará énfasis en el desarrollo sostenible, dado que en las leyes de Colombia (Art. 3 Ley 99 de 1993 - 2000), se enuncia que el desarrollo sostenible es una forma de lograr crecimiento económico disminuyendo la utilización de recursos naturales e impactos perjudiciales sobre estos, llevando así a cabo un aumento del ingreso per cápita en la formulación y desarrollo de proyectos. Así pues, de manera pertinente, entendiendo el contexto social y ambiental del municipio de Cogua, se realiza una serie de propuestas que cumplan con las reglamentaciones nacionales y estén en armonía con el desarrollo sustentable, este permite que el buen uso de los recursos naturales continúe en el tiempo y conduce al desarrollo de la zona.
¿Qué resulta de los resultados de aprendizaje?
Authors: Trefftz Helmuth , Peláez Valencia Luis Eduardo
Published: January 2023

Diferentes organismos relacionados con procesos de evaluación y acreditación de la educación superior en el mundo han involucrado desde hace varias décadas, como una parte muy importante del proceso de acreditación, los Resultados de Aprendizaje (RA). La normatividad de la evaluación de la calidad en Colombia introdujo el tema en el país en el año 2019 con el decreto 1330 del Ministerio de Educación y en el 2020 con el acuerdo 02 del CESU. La aproximación a los RA, definida en la norma colombiana, pone en el centro de la propuesta el proceso de mejoramiento de los programas de educación superior basado en valorar el grado en que los estudiantes van logrando los resultados de aprendizaje durante el proceso de formación. Cumpliendo con la norma, todas las instituciones de educación superior del país están estableciendo y consolidando políticas para la definición de los resultados de aprendizaje. De manera similar los programas, para sus procesos de registro calificado y acreditación, han definido procesos para valorar los RA y para definir y hacer seguimiento a las acciones de mejora relacionadas. Los autores han conocido, de primera mano, procesos de varias instituciones que las han llevado a reflexiones académicas profundas como resultado de la definición e implementación de los RA. Sin embargo, las instituciones, con frecuencia, se preguntan cuáles transformaciones se pueden esperar cuando se hace una implementación adecuada de los RA. Este trabajo reporta la sistematización de los resultados de conversaciones de los autores con diversas agencias de aseguramiento de calidad internacionales que han implementado RA como parte sus procesos de evaluación y acreditación; indagando acerca de las transformaciones que se dan típicamente como resultado de implementar los RA. Estas transformaciones estarán agrupadas en los efectos sobre los diferentes actores del proceso de educación, esto es: estudiantes, profesores, egresados y empleadores.
Uso de la gamificación en la concientización de los habitantes aledaños al parque ecológico la Nitrera sobre el impacto que generan sobre él, las tareas domésticas y agrícolas
Authors: López Herrera Diana , Hernández Atilano Esnedy
Published: January 2023

El parque natural la Nitrera es una reserva natural de tipo bosque húmedo de montaña baja, se encuentra en el municipio de Concordia, al suroeste del departamento de Antioquia, posee un embalse que es la única fuente de abastecimiento de agua del municipio. El crecimiento de la población, la deforestación, la introducción de animales y plantas no endémicas de la zona, el incremento de los cultivos, el mal manejo de los residuos domésticos y agrícolas, entre otros factores han generado una transformación radical en el ecosistema, amenazando tanto el parque como el abastecimiento de agua al municipio. Los grupos de investigación GEOLIMNIA y GEPAR de la Facultad de Ingeniería de la Universidad de Antioquia, han realizado investigaciones sobre el ecosistema del parque y sus afectaciones. La socialización de los resultados a la comunidad requería de herramientas innovadoras, lo que dio vía a este trabajo, en el cual se diseñaron una serie de herramientas gamificadas que ayuden a los estudiantes e investigadores de la universidad a realizar procesos de sensibilización con la comunidad sobre cuidado del embalse y la apropiación de este por parte de la misma. Se desarrolló una la Cartilla Aumentada aplicando los conceptos de la estrategia didáctica Praccis es un estilo de enseñanza basado en los procesos hermenéuticos que guían una conversación para facilitar la circulación de los conocimientos desde el mundo de las ciencias hacia el mundo de la vida. Se desarrollo un videojuego para móviles y una hipermedia para la web bajo una metodología SUM adaptación de la metodología SCRUM. Logrando con estos 3 elementos una transmedia que va desde el papel hasta la realidad aumentada, con el fin de llegar a personas con diferentes niveles de escolaridad o nivel de alfabetización digital.
Marketplace de comercialización en la nube para el fortalecimiento de emprendimientos de excombatientes
Authors: Bonfante María , Blanquicett Benavides Luis Alfredo , Moscote Casseres Wilson
Published: January 2023

La Internet ofrece oportunidades para que las empresas de cualquier tamaño utilicen las aplicaciones de mercado electrónico soportadas en la nube con el fin de gestionar las interacciones empresa-consumidor de manera eficaz. Con el objeto de aprovechar esta tendencia, existe la oportunidad de crear nuevos nichos de mercados y fidelizarlos, por lo que se propone un proyecto de investigación cuyo objetivo es la construcción de una plataforma marketplace que permita transformar procesos de compra y venta de productos de 19 cooperativas beneficiarias de la Fundación Evolución Caribe que atiende población en posconflicto de los departamentos de Bolívar, Sucre, Cesar y Guajira. Inicialmente se realiza una revisión de los trabajos relacionados con la comercialización de diferentes productos, las tendencias y tecnologías utilizadas para la construcción de marketplace. La metodología utilizada corresponde al ciclo de vida de desarrollo de sistemas, el cual propone las fases de análisis de requerimientos, diseño, desarrollo y pruebas del sistema. Los resultados describen el prototipo construido integrando una arquitectura soportada en capas, con componentes y tecnologías que posibilitan las funcionalidades identificadas en la fase de análisis de requerimientos y que permiten hacer negocios con clientes y entre las mismas cooperativas de forma confiable. El frontend del sistema se construyó en el CMS WordPress y está disponible en: https://cloud-webservice.com/evolucioncaribe/marketplace/. En cuanto al backend, la capa de presentación Integra la vista del comprador, en la cual puede seleccionar un catálogo diversificado de productos, ver el detalle, seleccionar la cantidad y puede efectuar la compra y pago a través de los medios que la cooperativa tenga disponibles. Por otra parte, la vista del vendedor permite crear el catálogo de sus propios productos, realizar ofertas y revisar el historial de sus pedidos. La vista del administrador del sistema permite configurar los parámetros y generar los reportes estadísticos requeridos para el análisis y toma de decisiones a partir de indicadores. Finalmente se concluye que este proyecto es un esfuerzo de la academia para posibilitar el cierre de la brecha digital, apostarle a la sostenibilidad de emprendimientos de comunidades en posconflicto y salir de sus condiciones de vulnerabilidad.
Fictional Modality and the Intensionality of Fictional Contexts
Authors: Uckelman Sara L.
Published: January 2023

In (Kosterec 2021), Kosterec attempts to provide ``model-theoretic proofs'' of certain theses involving the normal modal operators $\Diamond$ and $\square$ and the truth-in-fiction (`a la Lewis) operator $F$ which he then goes on to show have counterexamples in Kripke models. He concludes from this that the embedding of modal logic under the truth-in-fiction operator is unsound. We show instead that it is the ``model-theoretic proofs'' that are themselves unsound, involving illicit substitution, a subtle error that nevertheless allows us to draw an important conclusion about intensional contexts (such as fictional contexts) and semantic equivalences.
Pure Refined Variable Inclusion Logics
Authors: Szmuc Damian , Rubin Mariela
Published: January 2023

In this article, we explore the semantic characterization of the (right) pure refined variable inclusion companion of all logics, which is a further refinement of the nowadays well-studied pure right variable inclusion logics. In particular, we will focus on giving a characterization of these fragments via a single logical matrix, when possible, and via a class of finite matrices, otherwise. In order to achieve this, we will rely on extending the semantics of the logics whose companions we will be discussing with infectious values in direct and in more subtle ways. This further establishes the connection between infectious logics and variable inclusion logics.
Assessement Methods of an Entity’s Economic Risks in Compiling the Accounting Policy
Authors: Kasyanova S. A.
Published: January 2023

The accounting policy of any economic entity is a strategically important tool for organizing accounting processes. Obviously, the assessment of economic activity risks affecting the choice of the most optimal accounting method allows it to identify the degree of impact of an event on the formation of accounting (financial) reporting indicators and prevent its material misstatements. Currently, in the Russian Federation, there is no methodology for assessing the risks of economic activity conducted at the legislative level for commercial organizations. The author’s working out presented in the paper fills the gap. This development is necessary in preparing the organizational, technical and methodological sections of the accounting policy of a commercial organization. It is based on the link between control procedures and risk assessment. The latter is stated in points, based on administrative responsibility for violation of the requirements for accounting and compiling of financial statements in Articles 15.11, 15.15.6 of the Code of Administrative Offenses. Also, it reflects the results of the audit, the nature of violations, and recommendations for their elimination. The study’s purpose works out a methodology for assessing the organization’s internal control system based on the development of methodological tools for identifying the consequences of the risk of economic activity at the stage of compiling the accounting policy of the commercial entity. The author used logical methods of cognition, system analysis and synthesis, modeling in practice. The significance of the results lies in deepening knowledge about the risk of economic activity, ways and methods of its assessment. The research gives a possibility to apply such tools and mechanisms in the organization’s internal control system.
Accounting and Statistics in China Under the Qing Dynasty
Authors: Amurskaya M. A.
Published: January 2023

The Chinese economy has been steadily showing growth and development for decades, which attracts the attention of the largest scientists around the world to the economic model of this country, business practices, accounting and statistics. The author conducted this study using the historical observation methods, comparison, sampling, systematization and generalization. Also, the author studied sources mainly in Chinese and analyzed publicly available publications in Russian and English. The research divided the features of the national economy growth during the Qing Dynasty into two historical periods: before the opium wars and in the post-opium period until the fall of the dynasty itself. The paper has given the main regulations governing the accounting and statistics of economic management, including the Laws of the Qing Dynasty and Regulations on the registration of households. The research has considered the basics of organizing statistics and accounting at the national level during the early and late Qing Dynasty, including the activities of the Ministry of Households, the Bureau of Statistics, the Bureau of Investigation, the Customs Administration and the China Post. The practical significance of the work for Russian specialists lies in the detailed coverage of national methods of accounting and statistics, such as the household registration Qianlong baojia, the system of tax books and acres segmentation, three-legged accounting, four-legged methods and Dragon Doors. The paper presents the main ideas and research results of such prominent Chinese thinkers in accounting and statistics as Gu Yanwu, Hong Liangji, Wei Yuan Wang Shiduo and Peng Zuzhi.
Ibiza and the introduction of capitalism in the Mediterranean: from agrarian self-consumption to full market dependence, 1857–1935
Authors: Cirer-Costa Joan Carles
Published: January 2023

In the second half of the nineteenth century, the primary sector expanded in Ibiza as in other Mediterranean regions. However, it also overcame the protectionist crisis at the end of that century and fully integrated into the international trade channels that emerged in the twentieth century. Within a few years, the island’s economy became fully dependent on foreign markets, as feeding the population and generating agricultural products overwhelmingly required external foodstuffs and inputs. The growth of the primary sector substantially improved the living conditions of Ibiza residents and incentivized the growth of associated sectors, including commerce and a merchant navy. It also permitted the accumulation of financial, human, and social capital that paved the way for Ibiza to become a leading international tourism destination in the 1930s.
Computational Approach for a Singularly Perturbed Differential Equations With Mixed Shifts Using a Non-Polynomial Spline
Authors: Ragula Kumar , Soujanya G. BSL , Swarnakar D.
Published: January 2023

In this paper, a second order singularly perturbed differential difference equation with both the negative and positive shifts is considered. A fitted non-polynomial spline approach is applied to solve the problem. Taylor series expansion process is being used to produce an approximated form of the considered problem, and then a fitted non-polynomial spline approach is devised in the form of a three-term recurrence relation. The convergence of the method is examined, and a quadratic rate of convergence is achieved. The maximum absolute error with quadratic rate of convergence of the solution is recorded. Layer profile is examined using the graphs.
Respiratory viral infections and their role in human cardiovascular diseases
Authors: Ilyicheva T. N. , Netesov S. V. , Abubakirova O. A. , Gureyev V. N.
Published: January 2023

Acute respiratory viral infections are the most common human diseases. Symptoms of the infection vary from a slight cold to critical condition requiring artificial lung ventilation and support of cardiovascular system. Main risk factors of severe disease include high viral load, co-infection with other pathogens, age from 0 to 2 years and older than 65 years, and immunodeficiency. Cardiac manifestations of the infection are usually caused by indirect effects due to inflammatory reaction resulting in systemic increase in proinflammatory cytokines, so called cytokine storm. However, there have been reports on the identification of respiratory viruses isolated directly from the myocardial tissue, or testing of viral RNA in the myocardium using real-time polymerase chain reaction. This review discusses the direct and indirect effects of respiratory viral infections on causing cardiovascular complications. The authors discuss the similarities and differences of the immunopathogenic mechanisms associated with COVID-19, influenza infection, as well as diseases caused by enteroviruses, respiratory syncytial viruses, metapneumoviruses, and parainfluenza viruses.
A case of clinical manifestation of unclassified cardiomyopathy during the new coronavirus pandemic
Authors: Barsukov A. V. , Borisova E. V. , Kozlov P. S. , Rud S. D. , Yasenovets M. V. , Akhmetshin I. M.
Published: January 2023

Isolated left ventricular non-compaction (LVNC) is a rare variant of unclassifiable cardiomyopathy (CMP). The basis of the clinical picture of non-compaction CMP is heart failure, arrhythmias, and thromboembolism. Acute cardiac and extracardiac diseases can act as a trigger for the LVNC manifestation. The paper provides an example of diagnosing LVNC in an adult patient after acute myocarditis against the background of vaccination against a new coronavirus infection COVID-19. The characteristics of the ongoing therapy are given and the dynamics of the course of the disease over a period of five months of observation is reflected.
A clinical case of SARS-CoV-2 infection complicated by acute respiratory distress syndrome, pulmonary edema, and heart failure in the presence of chronic venous congestion in a patient with chronic rheumatic heart disease
Authors: Vorobeva O. V.
Published: January 2023

The article presents a clinical case of SARS-CoV-2 infection complicated by acute respiratory distress syndrome, pulmonary edema, and heart failure in the presence of chronic venous congestion in a patient with chronic rheumatic heart disease. A female patient R., 65 years old, was hospitalized at the Republican Cardiological Dispensary with a diagnosis of novel coronavirus infection COVID-19 (severe course); the virus was identified. Competing diagnosis: (1) acute viral myocarditis;

(2) chronic rheumatic heart disease with combined mitral-aortic disease. Complications of the underlying disease included viral interstitial pneumonia (75%) and pulmonary edema. The patient was admitted at day 8 from the onset of the disease with complaints of increase in body temperature up to 38.5 °C, chest pain, and shortness of breath. She was treated in the outpatient setting without visible improvement. The patient had a history of chronic rheumatic heart disease. Due to persistent fever, patient received computed tomography showing interstitial pneumonia of viral etiology. The diagnosis of COVID-19 was based on a typical clinical presentation and a positive PCR test in nasopharyngeal swabs. Nonspecific changes were observed in the electrocardiogram. Treatment was initiated without positive dynamics, and a fatal outcome occurred. According to the autopsy data, the organs showed signs of chronic venous congestion (brown induration of the lungs, nutmeg fibrosis, cyanotic induration of the spleen and kidneys). The infiltrates consisting of lymphocytes and eosinophils were detected in the myocardium. Also, edema of the intercellular space, plethora of microvasculature vessels, and dystrophic changes in cardiomyocytes were detected. The presence of Aschoff-Talalaev granulomas with fibrinoid necrosis and avulsion of the chorda of the mitral valve leaflet was observed. Morphologically, there were signs of pulmonary infarction with a polysegmental character. Thus, in the presented case, the scientific novelty was the extremely rare development of mitral valve chord avulsion in aortic-mitral disease after infection with SARS-CoV-2, which was the cause of acute heart failure. It is likely that the process was aggravated by concomitant diffuse interstitial serous myocarditis and fibrinoid necrosis in granulomas.
Cardiovascular complications of respiratory viral infections
Authors: Ishmurzin G. P. , Serebryakova O. A. , Syuzev K. N. , Dolganova D. A. , Gainullina A. Kh.
Published: January 2023

Despite significant progress in understanding the pathogenesis and treatment of viral diseases, the influenza virus alone causes up to three to five million severe cases and 250-500 thousand deaths annually. However, respiratory viruses can affect not only the respiratory system, but also cause complications in the cardiovascular system. For example, acute coronary syndrome, myocarditis, pericarditis, exacerbation of chronic heart failure, acute heart failure, pulmonary embolism, and arrhythmias. This review provides information on the incidence of cardiovascular complications that occurred in association with acute respiratory viral infections (COVID-19, influenza, respiratory syncytial virus infection, adenovirus, and rhinovirus infections), and the mechanisms of respiratory virus impact on the cardiovascular system. Understanding these mechanisms may allow to predict the potential cardiovascular complications in patients with respiratory infections and take prompt measures to prevent them as soon as possible especially in case of life-threatening events.
SİCİLL-İ AHVAL KAYITLARINA GÖRE ANTALYALI MEMURLAR TARAFINDAN İŞLENEN SUÇLAR
Authors: AKPINAR Ozan Can
Published: January 2023

Osmanlı Devleti’nde, 19. yüzyılda bürokrasi ve memuriyet özelinde birtakım düzenlemeler yapılmıştır. Bu düzenlemeler özellikle Tanzimat döneminden itibaren hız kazanmış, memurluk mesleği modern ve rasyonel bir sisteme oturtulmaya çalışılmıştır. Ayrıca memurların işledikleri suçlara karşı uygulanacak yasal yaptırımlar da dönemin idarecilerinin gündeminde yer almıştır. Memurlarla ilgili rahatsız olunan hususların temelini ise rüşvet, yolsuzluk, hakaret, zimmetine para geçirme, görevi kötüye kullanma, izinsiz görev yerinden ayrılma, görevi yerine getirmeme ve ahlaksız bazı hareketlerde bulunma gibi müzmin suçlar oluşturmuştur. Sözü edilen suçlarının önüne geçilmesi ve yargılama sürecinin belli ilkelere göre yapılması amacıyla çeşitli kanun ve nizamnameler yayımlanmıştır. Ayrıca II. Abdülhamid dönemine gelindiğinde, denetimsizliğin önüne geçmek ve memur atamalarını düzenli bir şekilde yapabilmek amacıyla memurların biyografilerini kaydetmekle yükümlü olan Sicill-i Ahval Komisyonu kurulmuştur. Bu komisyon bünyesinde tutulmaya başlanan sicill-i ahval kayıtları ise 1879’dan itibaren sicill-i umûmî adı verilen defterlere kaydedilmiştir. Buradan hareketle çalışmada, sicill-i ahval kayıtlarından faydalanılarak Antalya merkez kazasında doğan Müslüman ve gayrimüslim memurların işledikleri suçlar ele alınacak, işlenen suçun niteliği ve suçu işleyen memurun akıbeti hakkında merkez-taşra ilişkisi bağlamında değerlendirmelerde bulunulacaktır.
STRUCTURAL AND DERIVATIONAL PARAMETERS OF THE SPORTS TERMINOLOGY
Authors: Pavliuk Alla , Rohach Oksana , Sheludchenko Svitlana , Yefremova Nataliia , Boichuk Valentyna
Published: January 2023

The paper is grounded upon the fact that the amount of vocabulary in the English language is expending and growing quickly, as its constant development and enrichment are both an obligatory condition and a direct consequence of the progress in the particular branches of human activity. It has been accentuated that all terms, fulfilling the applied function of the tools of cognition and means of fixing scientific and technological progress, are unified and fixed in the language. Based on this, the classification of terms has been done according to normativity – non-normativity.

Grounding on the number of already existing definitions, we understand a terminological phrase as a semantically integral word combination of two and more words connected by prepositions, or asyndetically. The correlation concerning the morphological structure of terms demonstrates a clearly expressed tendency of derivation being used as the main way of word-building in the development of sports terminological units. The conducted analysis of the studied mono- and multi-component terminological units showed that derivation is one of the most powerful sources of development of sport terminology. The corpus of sports terms can be described in accordance with the specialized spheres of use.

The amount of vocabulary in the English language is expending and growing quickly, as its constant development and enrichment are both an obligatory condition and a direct consequence of the progress in the particular branches of human activity. The dynamic development of sports contributes to its belonging to the social area and gains a global meaning. Sport is not only a purely professional activity of a person, but also a part of the cultural, political and economic life of the country, an integral segment of traditions and self-consciousness of the people. Sport draws attention of lots of specialists and scholars, in particular linguists, who study its verbal representation and treat sports terminology as a prior one.
THE OUTLINE OF CONTEMPORARY ENGLISH AND UKRAINIAN СOMPUTER SLANG LEXICON
Authors: Lynnyk Yurii , Navrotska Iryna
Published: January 2023

This article addresses computer English and Ukrainian computer slang as a lexical subsystem evoked to provide the Internet community with effective communication means. Slang lexicon fulfills a number of functions depending on the contextual features, level of professionalism of language users and their interest. Although it is argued by some scholars that slang words rarely undergo semantic changes, it has been revealed that in the process of adaptation in the target language lexical and grammatical transformations typically occur in computer slang. In particular, English computer slang words are adapted to the Ukrainian reality through the process of clipping, blending, adding inflections, conceptual metaphor and other figurative transfers of meaning. Interestingly, it is common for new forms to acquire connotations which are not found in the original language. Ridiculous associations help users to quickly connect the form and denotative meaning of a slang lexeme in question. The sources of computer slang formation include calque, telescopy, phonetic mimicry and translation. The knowledge of language community can significantly simplify the identification of hidden senses and related connotations in other similar words. Stratification of slang is a difficult task as well as its software implementation in online dictionary developments. The limitations of this research are related to complexity of establishing concise etymology and trace all relevant contextual features of slang units in the process of quickly evolving computer mediated communication.
UNWINDING THE SEMIOTICS IN SUSHEEL KUMAR SHARMA'S “UNWINDING SELF”
Authors: Yadav Dr. Nancy , Yadav Dr. Ramji
Published: January 2023

If direct observation can result in a literary genre of poetic art, analysis of selected poems in “Unwinding Self” becomes inevitable for the evaluation of diverse levels of poetic style, such as Japanese three-line haiku in mini-cantos of the Mahabharta, suggestive iconic-flashes on variable images and events in “Snapshots”, gender performitivity in “Bubli Poems” to gratify femininity with undertones of irony and many more which the poet experiments to prove his poetic mettle. The study attempts to find a formidable ground into the latencies of ‘empirical imagery’, which refer to the poet’s empirical mind that pervades into more than one iconic imagery or event at a time. The Poet’s multiple reflections which remain explicit or manifest in a chain of life-like sequences of variable structures with variable styles are concatenated dexterously in such a way that each poem invites the readers to dive into the poet’s wordplay, drawn on religions, contemporary events, relationships and allusions which the traditions tell in words and numbers. One becomes fanciful to decode the suggestive significance of “The New Year Dawn” with the appearance of ‘three stars’ representing “Orion’s Belt” for the new hunter in the imagery of Magi. The poet’s suggestive line – “Five times a day, my father’s/ Hands go up in the sky” - makes him agnostic and empirical about his Muslim father’s hands that can create colourful designs and build houses instead of knowing the unknowable Supreme. His poems can be approached with the term ‘suggestive objective correlative’ as the poet’s self-soul manifests in different identities, and each poem moves around the central metaphor, which sometimes becomes subtle due to the latent association with the places of visits, dates and years of events and the wordplay in numbers drawn from myths and legends, news, including literature; even the glossary in the collection sheds light on suggestive latencies.
Prototype Monitoring Kantung Cairan Infus Berbasis Internet Of Things (IOT)
Authors:   Universitas Hamzanwadi, Mahpuz Mahpuz , Bahtiar Hariman ,   Universitas Hamzanwadi, Sadali Muhamad ,   Universitas Hamzanwadi, Kurniawan Feni ,   Universitas Hamzanwadi
Published: January 2023

Infusion or intravenous therapy is the introduction of a fluid or drug into the body through the intravenous route at a constant rate over a certain period of time and is carried out continuously as a treatment measure. The extensive hospital conditions, coupled with the condition of different patients, infusion changes are often a common problem, such as infusion fluids that have run out but have not been replaced, which is a problem when patients have to be hospitalized. To overcome this problem, the Internet of Things (IoT)-Based Infusion Bag Monitoring Prototype is a prototype to assist medical personnel in monitoring the volume of fluid in the infusion bag remotely so as not to constantly check the patient's infusion in each room. The purpose of this study is to create an infusion bag weight monitoring device to monitor the volume of infusion fluid for each inpatient based on the internet of things (IoT) by utilizing the workings of a load cell sensor that functions to read infusion weight. As a microcontroller unit, it uses ESP8266 as a data uploader to the internet so that medical personnel can monitor the condition of the infusion bag for each patient through hospital devices, both computers and smartphones with the Blynk application.