bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case Study: Investigating High School English Student Engagement in Language Learning Through YouTube Music Videos
Authors: Feng Qiuhua , Guo Ziyue
Published: December 2024

This case study investigated high school student engagement in acquiring second language knowledge through YouTube music videos. A Chinese English learner who had lived in the United States for a year developed fundamental language skills but was hesitant to engage in language learning at the start of the project. Data collection was conducted over 10 weeks and involved semi-structured interviews, classroom observations, and in-class artifacts related to YouTube music learning activities. The findings indicated that the learner engaged with YouTube music videos from four perspectives: behavioral, emotional, social, and cognitive. From a behavioral perspective, singing recurring routines continuously engages the learner by promoting participation in language development. From an emotional and social perspective, music genres engage the learner through high affective input and peer interaction, facilitating the acquisition of cultural knowledge and daily communicative skill. From a cognitive perspective, multimodal features (e.g., lyrics and rhythm) stimulate the learner’s cognition by providing mnemonic aids that enhance memory for vocabulary and pronunciation competencies. Theoretical and pedagogical implications are provided for English language learning contexts, shedding light on the conceptual development of student engagement, multilingual teacher education, and multimodal learning. This study identifies future research trends in the instructional use of YouTube videos from multiple perspectives, including the transfer of working memory to long-term memory, digital multimodal composing (DMC), and generative AI.
Decision trees' viability and efficiency in forecasting coronary heart disease
Authors: M Jawahar  , S Monika
Published: December 2024

Cardiovascular disease is one of the most prevalent disease categories and a major global health concern. For therapy to be effective and survival chances to increase, early identification is essential. A decision tree in this instance is a trustworthy Classification technique for calculating cardiovascular disease hazard as well as gathering data for the clinical decision-making process. However, it may be difficult to find a more accurate simulation of cardiovascular illness due to scalability issues. Therefore, the performance and scalability of decision trees for the prediction of cardiovascular illness are investigated in this study. The study assessed a decision tree's ability to predict cardiovascular disease. The model complexity, cross-validation score, ratings of training result from augmented training samples, and error matrix were castoff to measure the enactment. The proceeding claims that model of decision tree had an accuracy with 89.8% in predicting the occurrence of cardiovascular disease. As a result, decision trees are useful for predicting and identifying cardiovascular disease incidents among patients early on.
Pemberdayaan Masyarakat dalam Menurunkan Kadar Gula Darah dengan Buerger Allen Exercise pada Pasien Diabetes Melitus
Authors: Nurjanah Candrawati Al , Aini Nurul , Herliyanti Dita Rizky , Nuradini Nuradini , Diel M. Martono , Haeriyah Siti , Kusumastuti Nurry Ayuningtyas , Marsepa Eva , Imanuddin Bayu
Published: December 2024

Diabetes Melitus (DM) adalah kumpulan beberapa gejala pada seseorang yang disebabkan adanya peningkatan kadar glukosa darah akibat penurunan sekresi insulin. Untuk mengatasi ketidakstabilan kadar glukosa darah dapat melalui dua cara yaitu cara farmakologi dan non farmakologi. Salah satu cara non farmakologi yang dapat digunakanan untuk menurunkan kadar glulosa darah adalah Terapi Buerger Allen. Kegiatan ini dilakukan dengan metode ceramah dan demontrasi. Populasi adalah responden dengan diagnosa medis DM di RW 01 dan RW 03 Kelurahan Koang Jaya. Pengumpulan data dengan menggunakan metode data sekunder dan observasi pada pasien DM yang dilakuan pemeriksaan kadar gula darah. Hasil dari pemberdayaan masyarakat inj dapat meningkatkan pengetahuan dan keterampilan pasien dalam penerapan terapi Buerger Allen untuk menurunkan kadar gula darah pada pasien DM.
Putusan Pengadilan Hubungan Industrial pada Pengadilan Negeri Jakarta Pusat di Masa Pandemi COVID-19
Authors: Sinaga Haposan Sahala Raja , Tobing Gindo L
Published: December 2024

This research legally analyzes the Industrial Relations Court Decision at the Central Jakarta District Court in Central Jakarta during the COVID-19 Pandemic. The issues that will be examined are reasons for filing a lawsuit for an industrial relations dispute that occurred during the COVID-19 pandemic and the judge's legal considerations in the Industrial Relations Court Decision at the Central Jakarta District Court Number 220/Pdt.Sus-PHI/2021/PN. Jkt.Pst. The research method is based on normative juridical legal research methods with a case approach of the Industrial Relations Court Decision at the Central Jakarta District Court Number 220/Pdt.Sus-PHI/2021/PN. Jkt.Pst Results of the Research: First, the reason for filing a lawsuit for an industrial relations dispute that occurred during the COVID-19 pandemic is seen from the Decision of the Industrial Relations Court at the Central Jakarta District Court with case number 220/Pdt.Sus-PHI/2021/PN.Jkt.Pst dated December 6 2021 is the occurrence of rights disputes and termination of employment due to force majeure conditions, namely the COVID-19 pandemic situation which is based on the issuance of Presidential Decree Number 12 of 2020 concerning the Determination of Non-natural Disasters. The Spread of Corona Virus Disease 2019 as a National Disaster. limiting business activities results in losses for business actors. Second, legal considerations in granting termination of employment based on the efficiency of the COVID-19 Pandemic (force majeure), based on the arguments of the Plaintiff's lawsuit along with evidence and witnesses of the Parties linked to the provisions of Article 45 paragraph (2) of Government Regulation Number 35 of 2021, so that the Panel of Judges assessed is legally grounded, therefore, based on justice and propriety, it is stated that the working relationship between the Plaintiff and the Defendant is terminated due to the efficiency reasons of the COVID-19 Pandemic (Force Majeure).
O SOCIALISMO ENQUANTO CONDIÇÃO POSSÍVEL PARA UMA FORMA DE VIDA (LEBENSFORM) DEMOCRÁTICA? UMA ABORDAGEM HONNETHIANA
Authors: Assai José Henrique Sousa
Published: December 2024

O debate a respeito do modelo socioeconômico capitalista e socialista permanece ativo nas sociedades atuais. Os pressupostos de ambos se estabelecem como irreconciliáveis entre si. Tentativas de diálogo, entretanto, para efeito de orientação à vida política e social têm sido feitos. No interior dessa querela reside um ponto de investigação – estudo e pesquisa – para a filosofia social e filosofia política: em um cenário capitalista de forma de vida organizacional, de que modo o socialismo ainda pode responder satisfatoriamente aos ditames da razão capitalista bem como aos seus desdobramentos que causam tanto sofrimento social?
Levando em consideração as assertivas supracitas, pretendo, neste artigo, explicitar, sob a perspectiva da pesquisa crítica (teoria crítica e filosofia social) o argumento honnethiano acerca do socialismo enquanto condição possível de se estabelecer como uma forma de vida democrática cujo fundamento se situa na efetividade da liberdade social (Soziale Freiheit).
A TRÍPLICE LIBERDADE NO PENSAMENTO DE AXEL HONNETH: JURÍDICA, MORAL E SOCIAL
Authors: Santos Luciano Gomes dos
Published: December 2024

O presente artigo tem por objetivo apresentar a tríplice liberdade no pensamento do filósofo social Axel Honneth: jurídica, moral e social. O método investigativo pauta-se na pesquisa bibliográfica. O pensador alemão desenvolve uma teoria da justiça que centra a liberdade na dimensão do reconhecimento. Para ele, a liberdade não se limita à esfera jurídica, mas se manifesta em três dimensões interligadas: a jurídica, a moral e a social. A liberdade jurídica está ancorada nos direitos individuais e na proteção estatal, enquanto a liberdade moral se relaciona com a autonomia individual e a capacidade de agir de acordo com princípios éticos. A liberdade social, por sua vez, está ligada à participação em comunidades e à construção de identidades coletivas. A realização plena da liberdade depende do equilíbrio entre essas três dimensões, e que as patologias sociais surgem quando o reconhecimento é negado em alguma dessas esferas.
ULTRALIBERALISMO NO BRASIL: UM BALANÇO CRÍTICO
Authors: Medeiros Richelly Barbosa de , Rech Hildemar Luiz
Published: December 2024

Este estudo investiga as dimensões da crise econômica, política e cultural que culminaram na ascensão da extrema direita reacionária e na implementação de uma agenda ultraliberal regressiva no Brasil (2014-2022), alicerçada no ajuste fiscal permanente, nas contrarreformas, na superexploração do trabalho e no contracionismo em relação aos gastos sociais com políticas públicas. Para tanto, avaliou-se a crise estrutural do capitalismo contemporâneo, de 2007/2008, e suas repercussões de longo prazo no Brasil, ressaltando a conjuntura na qual emergiu o recente projeto de aprofundamento da estratégia neoliberal, que ampliou a disputa pelo fundo público e, como será demonstrado, o desfinanciamento da política de Educação Superior e de Ciência & Tecnologia no país. Este estudo apresenta resultados parciais de tese de doutorado, submetida ao Programa de Pós-Graduação em Educação da UFC. O levantamento de dados ocorreu em parceria com o Centro de Estudos do Trabalho e Ontologia do Ser Social da UECE. A metodologia consistiu em uma revisão de literatura, acompanhada de levantamento de dados em fontes primárias e secundárias. Em síntese, foi possível identificar três fases do ultraliberalismo no Brasil: no final do primeiro mandato de Dilma Rousseff (esquerda), na gestão de Michel Temer (direita) e no governo de Jair Bolsonaro (extrema direita reacionária). Resguardadas todas as suas particularidades, o ultraliberalismo pôs em prática uma agenda draconiana de espoliação das rendas do trabalho e de rebaixamento das condições de vida da população.
Karyology of Prunella grandiflora and Prunella vulgaris from Turkey
Authors: Martin Esra , Dirmenci Tuncay , Satıl Fatih , Eroğlu Halil Erhan
Published: December 2024

Prunella L. species are distributed in very different habitats since they can adapt to variable ecological conditions. These conditions cause variations in morphological characters. It is very important to support morphological and taxonomic characters with genetic data. So far, various diploid numbers have been reported in the chromosomal records of Turkish Prunella species. The situation is particularly complex in P. vulgaris L. and P. grandiflora (L.) Turra species. The aim of this study is to eliminate the complexity by presenting karyological data of these species. The chromosome number and chromosome lengths of P. grandiflora and P. vulgaris were reported for the first time from Turkey. The diploid and basic numbers were detected as 2n = 28 and x =7 by ploidy levels of 4x in P. grandiflora and P. vulgaris. As a result, the karyology of the genus Prunella was evaluated by comparing previous and present results. The listed data provided important contributions to the cytotaxonomy of the genus Prunella: (i) the basic number was x = 7, (ii) the most common diploid number was 2n = 28, and (iii) high polyploidy rates. The polyploidy probably played an important role in the speciation of the genus.
Pengaruh Kerja Tim, Kepuasan Kerja, Niat Untuk Berhenti Terhadap Kinerja Karyawan
Authors: Nurdiannova Arief , Handu Atanasius
Published: December 2024

Every company needs quality employee performance to achieve company goals. This study aims to determine the effect of teamwork, job satisfaction, and intention to quit on employee performance. Teamwork is the implementation of work in groups in a company. Job satisfaction is a feeling of satisfaction with the work that has been done. Intention to quit is a feeling of wanting and trying to leave the current workplace according to the employee's wishes. Meanwhile, employee performance is the quality and quantity of employee work according to their responsibilities. The population used in this study were employees of PT. Multi Energy Nusantara as many as 75 respondents with census techniques, so that the sample obtained was also 75 respondents. Data were collected through a questionnaire survey and analyzed using multiple linear regression analysis. Based on the test results, it shows several conclusions that partially, teamwork does not affect employee performance, job satisfaction has a positive effect on employee performance, and employee intention to quit has an effect on employee performance at PT. Multi Energy Nusantara. Meanwhile, simultaneously teamwork, job satisfaction, and intention to quit have an effect on employee performance at PT. Multi Energy Nusantara.
Analisis Uji Pengaruh Karakteristik Pekerjaan, Kepuasan Kerja Karyawan dan Budaya Organisasi Terhadap Komitmen Organisasi pada Perusahaan Logistik Pelabuhan
Authors: Devi Yesica N , Akseptori Ristanti , Hardiyanti Fitri
Published: December 2024

Getting skilled human resources is not easy because of the increasingly tight competition, so it requires commitment for the company. In a port logistics company in Surabaya, there was a decrease in the number of employees due to early retirement. In addition, the increase in the number of management work plans caused an unbalanced workload. So that it causes work stress in employees. This study aims to analyze the influence of job characteristics, employee job satisfaction, and organizational culture on organizational commitment in a port logistics company in Surabaya. This study used a multiple linear regression analysis method with the help of SPSS 26. The number of respondents was 81 company employees. The results of this study indicate that job characteristics, job satisfaction, and organizational culture have a positive and significant effect on organizational commitment both partially and simultaneously. The coefficient of determination (R2) produced is 0.521, which means that the independent variable explains 52.1% of the variability of organizational commitment, while the remaining 47.9% is influenced by other variables outside this study. So it can be concluded that in this study there is an increase in job characteristics that are in accordance with employee abilities, high job satisfaction, and a supportive organizational culture can increase organizational commitment.
A Facile Review on the Legal Issues concerning the Implementation of the Administration of Criminal Justice Act of Nigeria
Authors: Aidonojie Paul Atagamen
Published: December 2024

No doubt that the Administration of Criminal Justice Act of Nigeria 2015 brought innovative provisions in ensuring justice is served to the society. However, despite the innovative provision of the Act, there seem to be a high level of maladministration of justice. Given this, the study undertook doctrinal and non-doctrinal research on how effective the police, the prison officers, the office of the Attorney-General of Nigeria, and the court have been able to enforce their functions as provided by the ACJA of Nigeria. The study used online survey questionnaires sent to 302 legal practitioners (randomly selected) in Nigeria, given their pragmatic knowledge of ACJA of Nigeria. A descriptive and analytical statistic was used to analyse the respondentsâ€™ response in ascertaining if the above ministers of justice have been effective in enforcing their roles as specified by ACJA of Nigeria. Given the data generated, the study found that there has been a lapse in the effective implementation of ACJA in Nigeria. It was therefore concluded and recommended that the Administration of Criminal Justice Monitoring Committee set up by the ACJA of Nigeria need to exact their duties in check-mating the police, the office of AG of Nigeria, and the courts to ensure the maximum enforcement of their functions.
Legal Problems of Cancellation of Deed of Sale and Purchase of Land Rights Due to One of the Parties Committing Default
Authors: Kholid Muhammad Idham
Published: December 2024

This study aims to analyze: 1) Legal problems of land rights sale and purchase because one party is in default. 2). Legal protection for the injured party due to the cancellation of the land rights sale and purchase deed because one party is in default. This type of research is included in the scope of normative legal research. The approach method in this study is the statute approach. The type and source of data in this study are secondary data. obtained from literature studies. The analysis in this study is descriptive analytical. The results of the study concluded: 1). Legal problems of land rights sale and purchase because one party is in default, namely the party who feels aggrieved has the right to sue the Court to claim compensation, in the form of compensation for costs, losses and interest. Default causes legal certainty to be disturbed because the other party becomes uncertain about their rights and obligations. 2) Legal protection for the injured party due to the cancellation of the land rights sale and purchase deed because one party is in default, namely must include preventive and repressive measures. With preventive measures, such as making clear deeds and checking the legality of the land, as well as repressive measures, such as lawsuits and enforcement of sanctions, the legal system can provide comprehensive and effective protection for the injured party. This approach ensures that the law not only functions as a dispute resolution tool but also as a preventive mechanism that maintains justice and legal certainty in land sale and purchase transactions. However, legal protection does not apply to all buyers but only applies to certain buyer criteria. The criteria for buyers who are protected are those who have good intentions.
Islamic Law in National Legal System (Theory of Applicability, Development and Implementation in Indonesia)
Authors: Wahyudi Trubus
Published: December 2024

Indonesia is a country of law based on Pancasila and the 1945 Constitution of the Republic of Indonesia, upholding ethical values and moral values, as well as the noble personality of the nation, believing in and being devoted to God Almighty, and respecting diversity in social, national and state life, and protecting the dignity and honor of every citizen. The Unitary State of the Republic of Indonesia also aims to realize an orderly, clean, prosperous and orderly life in the life of the nation, state and society. ExistenceIslamic law is closely related to the Islamic religion which is always interesting to study and discuss, because the majority of the population of Indonesia is Muslim. Because Islamic law always follows and cannot be separated at all from the "Principle of Islamic Personality" where people who adhere to Islam are located. The existence of Islamic law has long been understood as an inseparable part of the awareness of Indonesian society regarding law and justice, the existence of which is clear within the framework of contribution as raw material for national law, even as a form of transformation of Islamic law into the national legal system.
An innovative evaluation of microstructure and tribological behavior of AISI 1060 and CuZn37Pb2 under laboratory and complex working conditions
Authors: Bougoffa Mohammed seyf eddine , Benchaa Sayhia , Abdelhak Hadibi , Ouissem Benmesbah , Sihem Benkhaled , Yasmine Labiod
Published: December 2024

Wear is a significant industrial issue caused by the interaction of multiple complex factors rather than solely by material properties. CuZn37Pb2 and AISI 1060 steel are particularly susceptible to wear due to extensive industrial applications. This study developed a wear test tool, machined on a horizontal lathe, for testing under dry and lubricated conditions. A tribological comparison was conducted between the lathe test and a tribometer, examining factors like surface roughness, load, sliding speed, wear track diameter, track width, contact temperature, wear loss, and wear rate relative to the friction coefficient. Experiments were performed with torques ranging from 25 to 100 N, speeds of 0.30, 0.40, and 0.50 m/s, and wear track diameters of 4, 6, 8, and 10 mm. Worn surfaces and wear tracks were analyzed using optical microscopy and SEM-EDS. The influence of temperature (50 °C to 200 °C) on friction properties was studied, showing that sample morphology and test type greatly affect tribological response. Despite a wear rate calculation error below 8.12%, results indicated differences between laboratory and real-world tribological responses. This study enhances wear understanding by examining numerous previously unstudied characteristics and shows that, although wear cannot be entirely eliminated, it can be significantly minimized. Laboratory testing provides prototypes for industrial challenges, effectively linking academic research with industry needs.
Urinary incontinence due to estrogen deficiency in dogs
Authors: Gök Çağla
Published: December 2024

Nowadays, various methods are used to control reproduction in domestic animals. The most commonly used method is ovariohysterectomy, in which the ovaries and uterus are removed together. In this review, an overview will be made of urinary incontinence due to estrogen deficiency, which is one of the complications that may occur after this operation, which is performed in almost every clinic, and which can negatively affect the life of the patient and the patient's relative. The exact mechanism involved with this condition is not yet fully understood but estrogen deficiency with a subsequent loss of urethral tonus is believed to trigger clinical signs. Also, information about the risk of urinary incontinence in animals that have undergone early ovariohysterectomy will be given.
Hematological and blood biochemical differences in dogs with mammary dysplasia/ hyperplasia, bening or malignant mammary tumors
Authors: Hacıoğlu Orkun , Aksu Rabia Buse , Akgül Sinem Yaren , Toydemir Karabulut Tuğba Seval Fatma
Published: December 2024

Mammary tumors are the most common neoplasms in female dogs. There are many factors involved in the development of mammary tumors. Recently, there is an increasing need for cost-effective prognostic markers derived from hematological parameters in dogs and cats with cancer. Our study was designed as a retrospective study to determine the significance of hematologic parameters in female dogs bearing with mammary tumors. For this, hematocrit (HCT), blood biochemistry, and some clinical and histopathological findings of female dogs with mammary gland masses that had undergone mastectomy (n = 100) were included in our study. Mammary masses in female dogs are divided into five histopathological groups: Group 1 (malignant epithelial tumors), Group 2 (malignant mesenchymal tumors), Group 3 (malignant mixed tumors), Group 4 (benign tumors) and Group 5 (hyperplasia/dysplasia). The following hematologic parameters were evaluated: leukocytes (WBC), neutrophils (NEU), lymphocytes (LYM), monocytes (MON), eosinophils (EOS), basophils (BAS), erythrocytes (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), platelets (PLT),mean platelet volume (MPV), and neutrophil to lymphocyte ratio (NLR). Biochemical analysis included blood urea nitrogen (BUN), creatinine (CRE), alanine aminotransferase (ALT), glucose (GLU), total protein (TP), alkaline phosphatase (ALP), and albumin/globulin ratio (AGR). Comparisons were made between the groups according to histopathological tumor types. The most common histopathological type after mastectomy is malignant epithelial tumors (72%). For TP, a difference was found between G1 and G5 (p 0.05). For MON, a difference was found between G1 and G5, between G2 and G5, between G3 and G5, between G1 and G4, between G3 and G4 (p 0.05). For PLT, a difference was found between G2-G3 and G3-G4 (p 0.05). Although NLR was different between the groups and gets higher values with malignancy no statistical significance was found between the groups (p 0.05). While our study revealed some potential associations between hematologic parameters and histopathological tumor types, further studies with a larger and more diverse canine population are needed before these parameters can be reliably used as prognostic markers in female dogs with mammary masses.
Organic and inorganic minerals in Sonali chicken diets: Effect on growth performance and meat quality
Authors: Jaman Md. Arafat
Published: December 2024

Background: This study investigated the effects of inorganic minerals and organic trace minerals supplementation on the production and carcass characteristics of Sonali chickens. Materials and methods: A total of 180 Sonali chicks (RIR and Fayoumi cross) were randomly divided into 4 experimental groups, each group occupying 3 replications. Dietary groups were considered as control (T0), organic trace minerals at 100 g/100 kg feed (T1), inorganic minerals at 250 g/100 kg feed (T2), and organic trace minerals at 100 g/100 kg feed + inorganic minerals at 250 g/100 kg feed (T3), respectively. Weekly body weight and feed intake data were taken to 60 days. Results: Initial body weight was not significantly different among the experimental groups (P 0.05). But the final body weight was significantly different among the experimental groups (P 0.05), with the highest value recorded at T3 (857.67 g). Total body weight gain was significantly different among the experimental groups (P<0.05) and was the highest value recorded in the T3 group (833.99 g). Total feed intake was non-significant among the experimental groups. Feed conversion ratios differed significantly among the experimental groups (P 0.05), with the lowest but best FCR found in the T3 group (1.96). Daily live weight gain was significantly different among experimental groups (P 0.05). Carcass weight, breast, thigh, and drumstick weights were significantly different among the dietary groups (P 0.01). Faecal ash (17.33%) and calcium (2.10%) secretion was lower in the organic trace minerals(T1) group than in the inorganic minerals(T2) group as well as the combined group, but phosphorus secretion (2.65%) was lower in the combined(T3) group than in the organic trace minerals group and the inorganic minerals group. The experimental groups differed considerably (P 0.01) in net profit, with T3 having the highest value (39.47 Bangladeshi taka) and T0 having the lowest (17.04 BDT). The benefit over control differed considerably (P< 0.01) among the experimental groups, with the highest value in the T3 group (22.43 BDT) and the lowest in the T2 group (6.89 BDT). Conclusion: So, Sonali commercial farmers may combine organic trace minerals and inorganic minerals with basal feeds to increase Sonali chicken production efficiency and profit.
Gamification in a Flipped Classroom Using Articulate Storyline for Junior High School Students’ Vocabulary Mastery
Authors: Putri Intan Permata Agustin , Arifani Yudhi , Asari Slamet
Published: December 2024

This study aims to design gamification-based- instructions using articulate storyline in a flipped classroom setting to improve vocabulary mastery of junior high school students and to examine how students’ perspective on this approach compared to traditional methods. The study employs a Research and Development (R&D) methodology, guided by the ADDIE model (Analysis, Design, Development, Implementation, Evaluation). The results show that there is a significant improvement in students’ vocabulary mastery, with an average gain of 30%, and over 85% of students found the gamified activities significantly more engaging and motivating. The study concludes that using the Articulate Storyline in conjunction with gamification in a flipped classroom environment significantly improves both student engagement and vocabulary mastery. These findings provide not only insightful information that positions gamified learning as a strong substitute for conventional pedagogy but also further advancements in instructional design.
Ameliorative Effect of Topical Clinoptilolite on 2,4- Dinitrof luorobenzene Induced Atopic Dermatitis Model in Mice
Authors: Gülbenli Türkoğlu Büşra , Albay Metin Koray , İpek Volkan
Published: December 2024

Atopic dermatitis is a multifactorial disease process. It is defined as "a genetically predisposed inflammatory and itchy allergic skin disease associated with the production of immunoglobulin E against environmental allergens". Experimental models are considered important in the evaluation of therapeutic agents for the treatment of atopic dermatitis. This study aimed to reveal the effects of clinoptilolite and tacrolimus on atopic
dermatitis lesions in the atopic dermatitis model in mice induced with 2,4-dinitrofluorobenzene. For inducing the atopic dermatitis model, mice were administered topically on the back with 0.15% 2,4-dinitrofluorobenzene twice a week for 5 weeks. For the next 4 weeks, 0.15% 2,4-dinitrofluorobenzene was applied once a week to maintain inflammation. Afterward, topical tacrolimus cream (0.1%) and topical clinoptilolite powder
were used for 4 weeks. Clinical score, serum thymus and activation-regulated chemokine, histopathology, and thymic stromal lymphopoietin (TSLP) immunostainings were evaluated between groups. While clinoptilolite treatment was found to be effective in the normalization of clinical scores, serum thymus and activation regulated chemokine levels were found to be variable and insignificant. Histopathologically, clinoptilolite
had an ameliorative effect on epidermal thickness and inflammation yet there was no significant difference of mast cells and fibrosis between groups. Furthermore, clinoptilolite had an inhibitory effect of TSLP immunostaining on epidermal tissue. In conclusion, clinoptilolite could be an alternative treatment of atopic dermatitis with its effects similar to tacrolimus.
Investigating the Perception of Internal Audit in Women's Cooperatives: The Case of Isparta Province
Authors: Gök Ayşe Gül , Öztürk Mahmut Sami
Published: December 2024

Today, women's cooperatives, whose numbers are increasing, are among the organizations whose establishments are supported in Turkey. The main subject of our study is to investigate the internal audit perceptions of the partners of women's cooperatives, which have encountered various problems in their operation after their establishment. The study covers women's cooperatives in Isparta center and its surroundings. In this regard, a qualitative research was conducted with women's cooperatives that agreed to participate in the study. Qualitative data obtained with the semi-structured interview form were analyzed with the MAXQDA 2020 program and code schemes were created and interpreted. As a result of the study, it was concluded that the concept and mechanisms of internal audit are not fully known and are not carried out effectively. In addition, it has been concluded that the members do not have full information about the main organs of the cooperative, that cooperatives are generally reluctant to recruit partners, that organ activities generally remain on paper, that risk management is weak, and that there may be erroneous or fraudulent behavior in some cooperatives.
Analisis Dan Perancangan Manajemen Proyek Sistem Informasi Layanan Jasa Menjahit
Authors: Ardila Desi , Yahfizham
Published: December 2024

Make a venture administration data framework for customized administration. Based on the desires investigation gathered through perceptions and interviews, the framework plan was executed utilizing the waterfall method. These steps include modeling, needs investigation, plan, coding, testing, and upkeep. Plan outcomes incorporate client graphs and course graphs, and client interfaces that encourage information administration. The expanded data administration framework should advance venture administration efficiency, timeliness and quality of benefits in the sewing benefits trade, which can benefit trade proprietors and clients.
 
Penelitian ini bertujuan untuk mengembangkan sistem informasi manajemen proyek untuk layanan jasa menjahit. Berdasarkan investigasi keinginan yang dikumpulkan melalui observasi dan wawancara, rencana kerangka kerja dijalankan dengan menggunakan metode waterfall. Langkah-langkah ini mencakup pemodelan, investigasi kebutuhan, rencana, pengkodean, pengujian, dan pemeliharaan. Hasil rencana menggabungkan use case diagram, class diagram dan antarmuka pengguna yang memudahkan administrasi informasi. Kerangka kerja data administrasi yang diperluas harus memajukan efisiensi administrasi usaha, ketepatan waktu dan kualitas manfaat dalam perdagangan manfaat jahit, yang dapat menguntungkan pemilik perdagangan dan klien.
Analisis Sentimen Twitter Ibu Kota Negara Nusantara Menggunakan Algoritma Naive Bayes, Logistic Regression dan K-Nearest Neighbors
Authors: Sativa Alisya Nisrina , Rizky Avinka , Imelda Putri  , Putri Juventia Adelia , Akhmad Irsyad  , Islamiyah
Published: December 2024

Indonesia plans to move its capital from Jakarta to eastern Kalimantan under the name Nusantara. On the other hand, the new capital-building plan of Nusantara in eastern Kalimantan is called a public policy expert that will squeeze the state's incomes and expenditure (APBN) budget post in the midst of massive spending on health care and economic recovery from the Covid-19 pandemic. The relocation plan harvested a number of citizens' opinions on Twitter. The sentiment analysis research was conducted to find out the response of tweets related to the transfer of the Indonesian capital after the passing of the ICT Act as well as the comparison of the number of positive and negative tweets. The analysis process involves processing text data, creating a word cloud, and applying regression algorithms like Logistic Regression, classifications like Naive Bayes and K-Nearest Neighbors to predict sentiment. The Naive Bayes model's accuracy is the best algorithm model achieving a precision of 0.9480, with precision 0.9399, recall 0.9609, and f1-score 0.9503. This research provides in-depth insight into public opinion related to the transfer of the state capital of Nusantara.
Cerium Oxide Blended Biodiesel: Machine Learning and Response Surface Methodology for Prediction of Responses
Authors: Kabudake Padmakar , Kharade Y. R. , Gavahane R. S. , Mhaske M. S.
Published: December 2024

Because of the rising demand for diesel, researchers are looking into finding a new alternative fuel. Biodiesel is an excellent alternative to neat diesel due to its renewable, biodegradable, and non-toxic nature. However, its response characteristics, such as brake thermal efficiency (BTE) and brake-specific fuel consumption (BSFC) should be predicted correctly. Thus, the present work includes the production of biodiesel from cottonseed oil with two-step transesterification and the investigation of response characteristics for a single-cylinder diesel engine fueled with Cerium oxide, i.e. nanoparticle additive (NA), which is blended cottonseed oil biodiesel. Compression ratio (CR) and NA levels have varied from 16 to 18 and 50 to 100 ppm, respectively. Input parameters, namely CR and NA levels are considered for the present investigation. The present study presents a novel method that uses deep learning-based surrogate modelling, a machine learning (ML) technique to forecast the responses. The optimum operating conditions are a CR of 18 and an NA level of 83.877 ppm. The study results demonstrate that the deep learning model provides a convincing substitute for classical regression models such as Random Forest, Decision Tree, Support Vector Machines, Gradient Boosting, and K-Nearest Neighbor Regressor. Further, multi-objective optimization of input parameters is performed using the desirability function approach. The optimized parameters were attained at a composite desirability of 0.847. Lastly, confirmation experiments are performed to validate the results of non-linear regression models and found satisfactory with an error percentage of less than five.
Possibilities of immunohistochemical markers HBME-1, TROP-2, Galectin-3 and Ki-67 to optimize the diagnosis of follicular carcinomas
Authors: Nechai O. P. , Belemets N. I. , Huz O. O. , Kvitka D. M. , Tovkai O. A.
Published: December 2024

In clinical practice, there is a diagnostic dilemma in the morphological examination in the verification of follicular carcinomas of the thyroid gland (FTC) and follicular adenoma (FA) among patients who were operated on for a nodular goiter with Bethesda III, IV and V cytological findings.
Objective — To study the effectiveness of the use of immunohistochemical (IGH) markers HBME‑1, TROP‑2, Galectin‑3 and Ki‑67 in the diagnosis of FA and FTC on the histological material of patients who were operated on for nodular goiter with a cytological conclusion according to the Bethesda classification III, IV and V.
Materials and methods. 124 patients operated on for follicular nodular neoplasms with a cytological conclusion according to Bethesda «Gray zone» were studied, as a result of the pathohistological examination, it was established: FTC — 26 (20.97%), FA — 98 (79.03%). IGH was performed using monoclonal antibodies against human HBME‑1, TROP‑2, Galectin‑3 and Ki‑67 («Bio SB», USA). Evaluation criteria were based on the intensity of staining (scale of 0 to 3)
Results. TROP‑2 and Ki‑67 markers provide the highest overall diagnostic efficiency due to high specificity (93.9% and 96.9%, respectively). However, their sensitivity is extremely low (11.5% — Ki‑67, 0% — TROP‑2). That is, these tests have practically no diagnostic utility. From the point of view of detecting the disease, the test based on HBME‑1 is the most useful (sensitivity — 88.5%): only 3 cases out of 26 were missed, but it gives a lot of false positives: 74 out of 98. The test based on Galectin‑3 relatively accurately determines the absence of the disease — correctly identified 78 out of 98 such cases (specificity — 79.6%), but at the same time it is practically ineffective in finding the disease — 9 «triggers» out of 26 cases of FTC. If there is a simultaneous absence of the reaction of the HBME‑1 and Galectin‑3 markers, with a probability of approximately 0.9, it can be expected that the patient does not have FTC. On the other hand, with the maximum strength of the reaction, the probability of detecting FTC reaches 0.667.
Conclusions. HBME‑1 (sensitivity 88.5%) turned out to be the most significant IGH marker in the differential diagnosis between FA and FTC. Markers TROP‑2 and Ki‑67 on the IGH study were practically not useful in the detection of FTC (sensitivity 0 and 11.5% respectively). The combined use of HBME‑1 and Galectin‑3 markers proved that the absence of an IGH reaction can be interpreted in favor of the presence of FA in the patient, and the simultaneous positive reaction of both markers is a warning regarding the diagnosis of FTC.
10 years of experience in providing surgical care to children with nodular and diffuse toxic goiter
Authors: Globa E. V. , Tovkai O. A. , Palamarchuk V. O. , Nechai O. P.
Published: December 2024

Objective — to study the structure of thyroid diseases in children who required surgical treatment, analyze their gender and age distribution, and assess preoperative, intraoperative, and postoperative courses for thyroid nodules (TN) and diffuse toxic goiter (DTG). The study also aimed to evaluate the frequency of early and late complications, disease recurrences, and further treatment approaches.
Materials and methods. This retrospective cohort study included 456 children (under 18 years of age) who underwent thyroidectomy at the Center between 2013—2022. According to the results of clinical and laboratory data and final pathohistological examination, all patients were divided into 3 groups: thyroid cancer (n=241), TN (n=151) and DTG (n=64). In the preoperative period, the duration of the disease, patients’ age, sex distribution, thyroid function, the results of instrumental examinations (thyroid ultrasound, FNAB with cytological assessment according to Bethesda) were investigated in patients with TN and DTG. In patients with TN and DTG, available for further postoperative follow up, the postoperative thyroid function, frequency of early and late complications and further treatment were studied.
Results. Among all thyroid diseases that required surgical intervention, thyroid cancer (52.8%) and female gender (75%) prevailed. The mean age of the operated children was 14.4±2.5 years. TN were significantly more frequent in pubertal age group (p <0.05). The mean duration of the disease before surgery in case of TN was shorter than in DTG (p <0.001). Thyroidectomy was most often done in DTG, and hemithyroidectomy (HT) and/or HT + lymphadenectomy (LD) in case of TN. In 21.3% of patients with TN after HT/HT + LD, euthyroidism was acheived. In patients with DTG in the late postoperative period, persistent hypoparathyroidism was the only and most frequent complication (n=2, 12.5%). In contrast, in TN in the late postoperative period, 7 patients (10%) were diagnosed with a relapse of the disease, which occurred more often in younger children (13.0 [13.0; 14.0] years) compared to the group without relapse (p=0.01). Treatment of relapse included follow‑up in the majority of patients with TN (71.4%).
Conclusions. Thyroid cancer predominated among thyroid diseases requiring surgical intervention. Persistent hypoparathyroidism was the only late complication in DTG cases. Considering the preservation of euthyroidism in 21.3% of patients with TN after HT/HT+LD, broader use of organ‑preserving surgeries should be considered, with further evaluation of postoperative hormone replacement therapy.
Influence of comorbidity on infectious complications and antibiotic resistance of pathogens following major liver resections in the setting of biliary obstruction
Authors: Romaniuk V. P. , Solovyova G. A.
Published: December 2024

Objective — to assess the impact of comorbidity on the incidence of postoperative infectious complications after major liver resections in patients with biliary obstruction
Materials and methods. The study included 105 patients who were divided into two groups: Group 1 — 53 patients with biliary obstruction (7 with hepatocellular carcinoma (HCC), 28 with cholangiocarcinoma (CC), 18 with colorectal cancer metastases), Group 2 — 52 patients without biliary obstruction (25 with HCC, 10 with CC, and 17 with colorectal cancer metastases). The patients were statistically homogeneous in terms of age and gender. The age of patients in group 1 was on average 60.2±10.7 years, group 2 — 63.5±11.4 years. A microbiological study of 632 isolates of bile (before and after extensive resection), urine, blood, sputum, pharyngeal and wound samples (once) was performed. The bacterial cultures were identified using a Vitek MS mass spectrometry Aanalyser with MALDI‑TOF technology.
Results. Patients with primary malignant and metastatic liver tumours and biliary obstruction have the following comorbidity associations: hypertension + heart failure, hypertension + heart failure + diabetes mellitus, hypertension + venous disease of the lower extremities + thrombophlebitis, hypertension + gastroesophageal reflux disease + chronic hepatitis, hypertension + hypothyroidism + metabolic‑associated steatotic liver disease; for patients with primary malignant and metastatic liver tumours without biliary obstruction — arterial hypertension + heart failure, arterial hypertension + heart failure + diabetes mellitus, arterial hypertension + gallstone disease, arterial hypertension + venous disease of the lower extremities + thrombophlebitis, arterial hypertension + bronchial asthma/chronic obstructive pulmonary disease, arterial hypertension + gastroesophageal reflux disease + chronic hepatitis.
Conclusions. Biliary obstruction in the setting of comorbidity statistically significantly increases the resistance of Enterococcus faecium strains to cefuroxime, levofloxacin, Staphylococcus aureus — to meropenem, levofloxacin, Klebsiella pneumoniae — to meropenem, cefuroxime, rifaximin, Acinetobacter baumannii — to meropenem, cefuroxime, levofloxacin, rifaximin, Pseudomonas aeruginosa — to cefuroxime, levofloxacin, rifaximin, Enterobacter spp — to meropenem, levofloxacin, rifaximin.
Karakteristik sensori dan aktivitas antioksidan snack bar berbahan dasar tepung sorgum dan labu kuning dengan penambahan ekstrak cassiavera (cassia bar)
Authors: Sudrajat Fathira Sakinah Anugrawati , Fauzi Muhamad Rizki , Qodariah Siti Nurlailatul , Sobarudin Muhammad Fahmi , Cahyasiam Riski , Aminullah Aminullah
Published: December 2024

Potensi kayu manis atau cassiavera dalam meningkatkan aktivitas antioksidan dalam suatu produk makanan sangat menjanjikan. Penelitian ini bertujuan untuk mempelajari penambahan ekstrak cassiavera terhadap karakteristik sensori dan aktivitas antioksidan produk snack bar yang berbahan dasar tepung sorgum dan labu kuning. Metode penelitian ini menggunakan rancangan acak lengkap (RAL) 1 faktor dengan 3 taraf perlakuan, yaitu penambahan cassiavera 5%, 7,5%, dan 10% dari bobot tepung sorgum dan labu kuningnya. Parameter yang diuji meliputi mutu sensori, hedonik, dan aktivitas antioksidan metode DPPH dan analisis data menggunakan ANOVA dan uji lanjut Duncan. Analisis statistik menunjukkan bahwa penambahan ekstrak cassiavera dalam produk snack bar meningkatkan aktivitas antioksidan yang terkandung dalam produk, namun cenderung menurunkan tingkat kesukaan produk snack bar pada beberapa parameter seperti rasa dan warna. Produk snack bar terpilih dengan metode De Garmo adalah snack bar dengan penambahan ekstrk cassiavera sebanyak 7.5%. Snack bar tersebut memiliki karakteristik warna coklat yang pekat, aroma cassiavera yang kuat, tekstur yang renyah, dan rasa pahit yang lemah dengan aktifitas antioksidan (IC50) sebesar 165.909 ppm.
Pengaruh Penambahan Stroberi (Fragaria Sp.) terhadap Karakteristik Fisik dan Kimia Velva Pisang Susu (Musa acuminata var. silk)
Authors: Lim Intan Junita , Maria Marina Herawati
Published: December 2024

Pisang adalah komoditi yang menarik untuk dikembangkan dan ditingkatkan produksinya. Tingginya tingkat produksi pisang di Indonesia tidak sebanding dengan tingkat konsumsi masyarakat hal ini mengakibatkan banyaknya pisang yang kurang dimanfaatkan dengan baik. Namun perlu adanya diversifikasi pangan, yaitu dengan cara membuat olahan pangan berupa velva. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan nanas madu terhadap karakteristik fisik yaitu overrun, daya leleh, total padatan terlarut dan karakteristik kimia yaitu total antosianin dan vitamin C serta memperoleh perlakuan yang terbaik. Penelitian ini, menggunakan metode Rancangan Acak Kelompok (RAK) dengan 4 perlakuan dan 1 kontrol, setiap perlakuan dilakukan 5 kali pengulangan sehingga diperoleh 25 sampel. Adapun perlakuannya terdiri dari K0 Kontrol buah pisang susu 200 g tanpa penambahan stroberi, K1 (Buah pisang susu 175 g + buah stroberi 25 g), K2 (Buah pisang susu 150 g + dengan stroberi 50 g), K3 (Buah pisang susu 125 g + dengan stroberi 75 g), K4 (Buah pisang susu 100 g + dengan stroberi 100 g). Hasil dari penelitian ini semakin banyak penambahan buah stroberi berpengaruh terhadap hasil velva pisang susu dan stroberi pada overrun yang semakin rendah dan daya leleh semakin tinggi, dengan total padatan terlarut , total antosianin dan vitamin C menurun.