bluuebunny/crossref_metadata_2025 huggingface dataset:
Managerial activity of future physical education teachers aimed at building a positive image using visual technologies
Authors: Ryskaliyev Sayat , Tuyakbayeva Meruyert , Kokebayeva Rysgul , Kazakhbayeva Gulnur , Gabitov Aidarbek , Kuderiev Janibek
Published: March 2024

With the integration of technology and social media in education, there is increasing interest in innovative approaches to enhance managerial skills among prospective physical education and sports teachers. The integration of technology and social media into education has prompted interest in exploring innovative methods to enhance the managerial skills of prospective physical education and sports teachers. This study investigates the impact of an intervention on the managerial skills of fourth-year students majoring in Physical Culture and Sports across three educational institutions in Kazakhstan. Out of 564 participants, 355 were eligible for analysis: 167 used chatbots and 188 followed conventional classroom methods. The intervention included a 4-week team management course starting in January 2022. Chatbot users accessed various materials such as short lecture videos, stories, assignments, infographics, and audio sequences, while conventional learners attended standard lectures and practical sessions. Following the course, participants undertook a 12-week teaching practice, with chatbot users also maintaining an active Twitter presence to build a positive image as future physical education teachers. Managerial skills were assessed using a 44-item questionnaire, covering Conceptual, Human, and Technical skills. Additionally, social media popularity was measured based on Twitter activity. Results showed that both groups significantly improved their Conceptual, Human, and Technical skills after the course. Chatbot users demonstrated greater improvement in Technical skills (p = 0.003, d = 1.139), while conventional learners showed stronger Human skills (p = 0.021, d = 1.32). Specifically, the mean score for Technical skills increased from 2.71 to 3.76 for chatbot users and from 2.65 to 3.20 for conventional learners. Moreover, chatbot-aided learners further enhanced their Conceptual and Human skills through social media engagement. Correlation analysis indicated a close relationship between managerial skills and social media popularity. These findings have significant practical implications for the education and development of prospective physical education and sports teachers. Integrating chatbots and social media into educational settings offers innovative approaches to enhancing managerial skills.
“R” U ready?: a case study using R to analyze changes in gene expression during evolution
Authors: Pomeroy Amy E. , Bixler Andrea , Chen Stefanie H. , Kerr Jennifer E. , Levine Todd D. , Ryder Elizabeth F.
Published: March 2024

As high-throughput methods become more common, training undergraduates to analyze data must include having them generate informative summaries of large datasets. This flexible case study provides an opportunity for undergraduate students to become familiar with the capabilities of R programming in the context of high-throughput evolutionary data collected using macroarrays. The story line introduces a recent graduate hired at a biotech firm and tasked with analysis and visualization of changes in gene expression from 20,000 generations of the Lenski Lab’s Long-Term Evolution Experiment (LTEE). Our main character is not familiar with R and is guided by a coworker to learn about this platform. Initially this involves a step-by-step analysis of the small Iris dataset built into R which includes sepal and petal length of three species of irises. Practice calculating summary statistics and correlations, and making histograms and scatter plots, prepares the protagonist to perform similar analyses with the LTEE dataset. In the LTEE module, students analyze gene expression data from the long-term evolutionary experiments, developing their skills in manipulating and interpreting large scientific datasets through visualizations and statistical analysis. Prerequisite knowledge is basic statistics, the Central Dogma, and basic evolutionary principles. The Iris module provides hands-on experience using R programming to explore and visualize a simple dataset; it can be used independently as an introduction to R for biological data or skipped if students already have some experience with R. Both modules emphasize understanding the utility of R, rather than creation of original code. Pilot testing showed the case study was well-received by students and faculty, who described it as a clear introduction to R and appreciated the value of R for visualizing and analyzing large datasets.
External validation of a minimal-resource model to predict reduced estimated glomerular filtration rate in people with type 2 diabetes without diagnosis of chronic kidney disease in Mexico: a comparison between country-level and regional performance
Authors: Sammut-Powell Camilla , Sisk Rose , Silva-Tinoco Ruben , de la Pena Gustavo , Almeda-Valdes Paloma , Juarez Comboni Sonia Citlali , Goncalves Susana , Cameron Rory
Published: March 2024

Background

Patients with type 2 diabetes are at an increased risk of chronic kidney disease (CKD) hence it is recommended that they receive annual CKD screening. The huge burden of diabetes in Mexico and limited screening resource mean that CKD screening is underperformed. Consequently, patients often have a late diagnosis of CKD. A regional minimal-resource model to support risk-tailored CKD screening in patients with type 2 diabetes has been developed and globally validated. However, population heath and care services between countries within a region are expected to differ. The aim of this study was to evaluate the performance of the model within Mexico and compare this with the performance demonstrated within the Americas in the global validation.

Methods

We performed a retrospective observational study with data from primary care (Clinic Specialized in Diabetes Management in Mexico City), tertiary care (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) and the Mexican national survey of health and nutrition (ENSANUT-MC 2016). We applied the minimal-resource model across the datasets and evaluated model performance metrics, with the primary interest in the sensitivity and increase in the positive predictive value (PPV) compared to a screen-everyone approach.

Results

The model was evaluated on 2510 patients from Mexico (primary care: 1358, tertiary care: 735, ENSANUT-MC: 417). Across the Mexico data, the sensitivity was 0.730 (95% CI: 0.689 – 0.779) and the relative increase in PPV was 61.0% (95% CI: 52.1% - 70.8%). These were not statistically different to the regional performance metrics for the Americas (sensitivity: p=0.964; relative improvement: p=0.132), however considerable variability was observed across the data sources.

Conclusion

The minimal-resource model performs consistently in a representative Mexican population sample compared with the Americas regional performance. In primary care settings where screening is underperformed and access to laboratory testing is limited, the model can act as a risk-tailored CKD screening solution, directing screening resources to patients who are at highest risk.
Sustainable forest management for nut and fuelwood production in the Jalalabad region, Kyrgyzstan: insights from local communities
Authors: Zhumasheva Aidai , Han Hee , You Joung Won , Park Pil Sun , Kang Kyu-Suk
Published: March 2024

Jalalabad region in the Kyrgyz Republic is home to the world’s largest natural walnut (Juglans regia L.) forests and pistachio (Pistacia vera L.) forests. These nut-fruit forests serve as the primary source of income for local people; however, deforestation has led to a decline in the availability of these resources. Wood from the forest is also used as a crucial energy source for cooking and heating in this region, despite state protection of the walnut forest due to a lack of alternative energy sources. This study aimed to explore solutions to restore nut-fruit forests while providing a fuelwood source and improving the income of local people. Qualitative research methods were employed, including semi-structured interviews and survey questionnaires with farmers and central and local government officials. The study investigated the main environmental problem of forest degradation and the challenges of forest management, such as livestock and complicated lease arrangements, and determined possible government support and incentives for local communities to participate in forest rehabilitation, such as planting instead of paying lease fees. The findings indicated that a tree-based farming approach can be a promising alternative land-use solution. Seventy-four percent of local farmers expressed their readiness to plant fruit trees and fast-growing tree species to meet their demand for fuelwood and improve their livelihoods if the government can provide temporary fencing support. The study also highlighted the need for capacity building for farmers to learn proper planting, managing, and harvesting for more sustainable practices. Policymakers need to modify legislation through simplified and incentive-based forest lease arrangements.
Prolonged dialysis during ex vivo lung perfusion promotes inflammatory responses
Authors: De Wolf Julien , Gouin Carla , Jouneau Luc , Glorion Matthieu , Premachandra Antoine , Pascale Florentina , Huriet Maxime , Estephan Jérôme , Leplat Jean-Jacques , Egidy Giorgia , Richard Christophe , Gelin Valérie , Urien Céline , Roux Antoine , Le Guen Morgan , Schwartz-Cornil Isabelle , Sage Edouard
Published: March 2024

Ex-vivo lung perfusion (EVLP) has extended the number of transplantable lungs by reconditioning marginal organs. However, EVLP is performed at 37°C without homeostatic regulation leading to metabolic wastes’ accumulation in the perfusate and, as a corrective measure, the costly perfusate is repeatedly replaced during the standard of care procedure. As an interesting alternative, a hemodialyzer could be placed on the EVLP circuit, which was previously shown to rebalance the perfusate composition and to maintain lung function and viability without appearing to impact the global gene expression in the lung. Here, we assessed the biological effects of a hemodialyzer during EVLP by performing biochemical and refined functional genomic analyses over a 12h procedure in a pig model. We found that dialysis stabilized electrolytic and metabolic parameters of the perfusate but enhanced the gene expression and protein accumulation of several inflammatory cytokines and promoted a genomic profile predicting higher endothelial activation already at 6h and higher immune cytokine signaling at 12h. Therefore, epuration of EVLP with a dialyzer, while correcting features of the perfusate composition and maintaining the respiratory function, promotes inflammatory responses in the tissue. This finding suggests that modifying the metabolite composition of the perfusate by dialysis during EVLP can have detrimental effects on the tissue response and that this strategy should not be transferred as such to the clinic.
Advancing kidney xenotransplantation with anesthesia and surgery - bridging preclinical and clinical frontiers challenges and prospects
Authors: Zhang Xiaojian , Wang Hailian , Xie Qin , Zhang Yang , Yang Yixin , Yuan Man , Cui Yuqi , Song Si-Yuan , Lv Jianzhen , Wang Yi
Published: March 2024

Xenotransplantation is emerging as a vital solution to the critical shortage of organs available for transplantation, significantly propelled by advancements in genetic engineering and the development of sophisticated immunosuppressive treatments. Specifically, the transplantation of kidneys from genetically engineered pigs into human patients has made significant progress, offering a potential clinical solution to the shortage of human kidney supply. Recent trials involving the transplantation of these modified porcine kidneys into deceased human bodies have underscored the practicality of this approach, advancing the field towards potential clinical applications. However, numerous challenges remain, especially in the domains of identifying suitable donor-recipient matches and formulating effective immunosuppressive protocols crucial for transplant success. Critical to advancing xenotransplantation into clinical settings are the nuanced considerations of anesthesia and surgical practices required for these complex procedures. The precise genetic modification of porcine kidneys marks a significant leap in addressing the biological and immunological hurdles that have traditionally challenged xenotransplantation. Yet, the success of these transplants hinges on the process of meticulously matching these organs with human recipients, which demands thorough understanding of immunological compatibility, the risk of organ rejection, and the prevention of zoonotic disease transmission. In parallel, the development and optimization of immunosuppressive protocols are imperative to mitigate rejection risks while minimizing side effects, necessitating innovative approaches in both pharmacology and clinical practices. Furthermore, the post-operative care of recipients, encompassing vigilant monitoring for signs of organ rejection, infectious disease surveillance, and psychological support, is crucial for ensuring post-transplant life quality. This comprehensive care highlights the importance of a multidisciplinary approach involving transplant surgeons, anesthesiologists, immunologists, infectiologists and psychiatrists. The integration of anesthesia and surgical expertise is particularly vital, ensuring the best possible outcomes of those patients undergoing these novel transplants, through safe procedural practices. As xenotransplantation moving closer to clinical reality, establishing consensus guidelines on various aspects, including donor-recipient selection, immunosuppression, as well as surgical and anesthetic management of these transplants, is essential. Addressing these challenges through rigorous research and collective collaboration will be the key, not only to navigate the ethical, medical, and logistical complexities of introducing kidney xenotransplantation into mainstream clinical practice, but also itself marks a new era in organ transplantation.
Serum phosphate levels and the development of sepsis associated acute kidney injury: evidence from two independent databases
Authors: Fang Yipeng , Zhang Yuan , Zhang Xin
Published: March 2024

Objective

We aimed to investigate the association between serum phosphate levels and the risk for developing sepsis associated acute kidney injury (SAKI).

Methods

Septic patients from the Medical Information Mart for Intensive Care IV (MIMIC IV) and the eICU Collaborative Research Database (eICU-CRD) were enrolled. Restricted cubic spline (RCS) was used to visualize the relationship between phosphate levels and the risk of SAKI. Patients were divided into four categories based on their serum phosphate levels. Logistic regression analysis, receiver operating characteristic (ROC) curve and subgroup analysis were performed to evaluate the predictive value of serum phosphate for SAKI.

Results

A total of 9,244 and 2,124 patients from the MIMIC IV and eICU-CRD database were included in the final analysis. RCS curve revealed a non-linear correlation between phosphate levels and the risk of SAKI (p for non-linearity <0.05). Each 1 mg/dL increase in phosphate levels was associated with a 1.51 to 1.64-fold increased risk of SAKI (OR 2.51–2.64, p < 0.001) in the MIMIC IV cohort and a 0.29 to 0.38-fold increased risk (OR 1.29–1.38, p < 0.001) in the eICU-CRD cohort. Compared to the normal-low category, hyperphosphatemia and normal-high category were independently associated with an increased risk of SAKI, while hypophosphatemia was independently associated with a decreased risk in the MIMIC IV cohort. A similar trend was observed in the eICU-CRD cohort, but statistical significance disappeared in the hypophosphatemia category and the adjusted model of normal high category. These finding was consistent in subgroup analysis.

Conclusion

Elevated serum phosphate, even within the normal range, is an independent risk factor for developing SAKI in septic patients. Abnormal change in serum phosphate levels may be a novel biomarker for early prediction of SAKI occurrence.
Insights into the defensive roles of lncRNAs during Mycoplasma pneumoniae infection
Authors: Yang Zhujun , Zhou Junjun , Su Nana , Zhang Zifan , Chen Jiaxin , Liu Peng , Ling Peng
Published: March 2024

Mycoplasma pneumoniae causes respiratory tract infections, affecting both children and adults, with varying degrees of severity ranging from mild to life-threatening. In recent years, a new class of regulatory RNAs called long non-coding RNAs (lncRNAs) has been discovered to play crucial roles in regulating gene expression in the host. Research on lncRNAs has greatly expanded our understanding of cellular functions involving RNAs, and it has significantly increased the range of functions of lncRNAs. In lung cancer, transcripts associated with lncRNAs have been identified as regulators of airway and lung inflammation in a process involving protein complexes. An excessive immune response and antibacterial immunity are closely linked to the pathogenesis of M. pneumoniae. The relationship between lncRNAs and M. pneumoniae infection largely involves lncRNAs that participate in antibacterial immunity. This comprehensive review aimed to examine the dysregulation of lncRNAs during M. pneumoniae infection, highlighting the latest advancements in our understanding of the biological functions and molecular mechanisms of lncRNAs in the context of M. pneumoniae infection and indicating avenues for investigating lncRNAs-related therapeutic targets.
Comparison of the gastrointestinal bacterial microbiota between dairy cows with and without mastitis
Authors: Guo Chunyan , Liu Jingjing , Wei Yong , Du Wen , Li Shengli
Published: March 2024

Mastitis causes significant losses in the global dairy industry, and the health of animals has been linked to their intestinal microbiota. To better understand the relationship between gastrointestinal microbiota and mastitis in dairy cows, we collected blood, rumen fluid, and fecal samples from 23 dairy cows, including 13 cows with mastitis and 10 healthy cows. Using ELISA kit and high-throughput sequencing, we found that cows with mastitis had higher concentrations of TNF-α, IL-1, and LPS than healthy cows (p < 0.05), but no significant differences in microbiota abundance or diversity (p > 0.05). Principal coordinate analysis (PCOA) revealed significant differences in rumen microbial structure between the two groups (p < 0.05), with Moryella as the signature for rumen in cows with mastitis. In contrast, fecal microbial structure showed no significant differences (p > 0.05), with Aeriscardovia, Lactococcus, and Bacillus as the signature for feces in healthy cows. Furthermore, the results showed distinct microbial interaction patterns in the rumen and feces of cows with mastitis compared to healthy cows. Additionally, we observed correlations between the microbiota in both the rumen and feces of cows and blood inflammatory indicators. Our study sheds new light on the prevention of mastitis in dairy cows by highlighting the relationship between gastrointestinal microbiota and mastitis.
Simple Scattering: Lipid nanoparticle structural data repository
Authors: Kim Lee Joon , Shin David , Leite Wellington C. , O’Neill Hugh , Ruebel Oliver , Tritt Andrew , Hura Greg L.
Published: March 2024

Lipid nanoparticles (LNPs) are being intensively researched and developed to leverage their ability to safely and effectively deliver therapeutics. To achieve optimal therapeutic delivery, a comprehensive understanding of the relationship between formulation, structure, and efficacy is critical. However, the vast chemical space involved in the production of LNPs and the resulting structural complexity make the structure to function relationship challenging to assess and predict. New components and formulation procedures, which provide new opportunities for the use of LNPs, would be best identified and optimized using high-throughput characterization methods. Recently, a high-throughput workflow, consisting of automated mixing, small-angle X-ray scattering (SAXS), and cellular assays, demonstrated a link between formulation, internal structure, and efficacy for a library of LNPs. As SAXS data can be rapidly collected, the stage is set for the collection of thousands of SAXS profiles from a myriad of LNP formulations. In addition, correlated LNP small-angle neutron scattering (SANS) datasets, where components are systematically deuterated for additional contrast inside, provide complementary structural information. The centralization of SAXS and SANS datasets from LNPs, with appropriate, standardized metadata describing formulation parameters, into a data repository will provide valuable guidance for the formulation of LNPs with desired properties. To this end, we introduce Simple Scattering, an easy-to-use, open data repository for storing and sharing groups of correlated scattering profiles obtained from LNP screening experiments. Here, we discuss the current state of the repository, including limitations and upcoming changes, and our vision towards future usage in developing our collective knowledge base of LNPs.
Artificial cognition vs. artificial intelligence for next-generation autonomous robotic agents
Authors: Sandini Giulio , Sciutti Alessandra , Morasso Pietro
Published: March 2024

The trend in industrial/service robotics is to develop robots that can cooperate with people, interacting with them in an autonomous, safe and purposive way. These are the fundamental elements characterizing the fourth and the fifth industrial revolutions (4IR, 5IR): the crucial innovation is the adoption of intelligent technologies that can allow the development of cyber-physical systems, similar if not superior to humans. The common wisdom is that intelligence might be provided by AI (Artificial Intelligence), a claim that is supported more by media coverage and commercial interests than by solid scientific evidence. AI is currently conceived in a quite broad sense, encompassing LLMs and a lot of other things, without any unifying principle, but self-motivating for the success in various areas. The current view of AI robotics mostly follows a purely disembodied approach that is consistent with the old-fashioned, Cartesian mind-body dualism, reflected in the software-hardware distinction inherent to the von Neumann computing architecture. The working hypothesis of this position paper is that the road to the next generation of autonomous robotic agents with cognitive capabilities requires a fully brain-inspired, embodied cognitive approach that avoids the trap of mind-body dualism and aims at the full integration of Bodyware and Cogniware. We name this approach Artificial Cognition (ACo) and ground it in Cognitive Neuroscience. It is specifically focused on proactive knowledge acquisition based on bidirectional human-robot interaction: the practical advantage is to enhance generalization and explainability. Moreover, we believe that a brain-inspired network of interactions is necessary for allowing humans to cooperate with artificial cognitive agents, building a growing level of personal trust and reciprocal accountability: this is clearly missing, although actively sought, in current AI. The ACo approach is a work in progress that can take advantage of a number of research threads, some of them antecedent the early attempts to define AI concepts and methods. In the rest of the paper we will consider some of the building blocks that need to be re-visited in a unitary framework: the principles of developmental robotics, the methods of action representation with prospection capabilities, and the crucial role of social interaction.
Pre-hospital stroke monitoring past, present, and future: a perspective
Authors: Ben Pazi Hilla , Jahashan Shady , Har Nof Sagi , Zibman Samuel , Yanai-Kohelet Ornit , Prigan Limor , Intrator Nathan , Bornstein Natan M. , Ribo Marc
Published: March 2024

Integrated brain-machine interface signifies a transformative advancement in neurological monitoring and intervention modalities for events such as stroke, the leading cause of disability. Historically, stroke management relied on clinical evaluation and imaging. While today’s stroke landscape integrates artificial intelligence for proactive clinical decision-making, mainly in imaging and stroke detection, it depends on clinical observation for early detection. Cardiovascular monitoring and detection systems, which have become standard throughout healthcare and wellness settings, provide a model for future cerebrovascular monitoring and detection. This commentary reviews the progression of continuous stroke monitoring, spotlighting contemporary innovations and prospective avenues, and emphasizes the influential roles of cutting-edge technologies in shaping stroke care.
Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage
Authors: Jamet Marguerite , Dupuis Luc , Gonzalez De Aguilar Jose-Luis
Published: March 2024

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal adult-onset neurodegenerative disorders that share clinical, neuropathological and genetic features, which forms part of a multi-system disease spectrum. The pathological process leading to ALS and FTD is the result of the combination of multiple mechanisms that operate within specific populations of neurons and glial cells. The implication of oligodendrocytes has been the subject of a number of studies conducted on patients and related animal models. In this review we summarize our current knowledge on the alterations specific to myelin and the oligodendrocyte lineage occurring in ALS and FTD. We also consider different ways by which specific oligodendroglial alterations influence neurodegeneration and highlight the important role of oligodendrocytes in these two intrinsically associated neurodegenerative diseases.
Efficacy of chronic neck pain self-treatment using press needles: a randomized controlled clinical trial
Authors: Horike Kaori , Ukezono Masatoshi
Published: March 2024

Background

Chronic neck pain is common among Japanese individuals, but few receive treatment. This randomized controlled trial aimed to evaluate the efficacy of acupuncture using press needles in the self-treatment of chronic neck pain and preliminarily identify the characteristics of patients likely to benefit from this treatment.

Methods

Fifty participants with chronic neck pain were allocated to receive either press needle or placebo treatment for 3 weeks. The visual analogue scale (VAS) and motion-related VAS (M-VAS) scores for neck pain, Neck Disability Index score, and pressure pain threshold were measured at baseline, after the first session, at the end of the last session, and 1 week after the last session. Changes in the outcomes were analyzed using analysis of variance, and the relationships between the variables were evaluated using structural equation modeling.

Results

Intervention results as assessed by VAS score revealed no significant differences in the ANOVA. A between-groups comparison of M-VAS scores at the end of the last session and baseline showed a significant difference (press needle: −21.64 ± 4.47, placebo: −8.09 ± 3.81, p = 0.025, d = −0.65). Structural equation modeling revealed a significant pain-reducing effect of press needle treatment (β = −0.228, p = 0.049). Severity directly affected efficacy (β = −0.881, p < 0.001). Pain duration, baseline VAS and Neck Disability Index scores were variables explaining severity, while age and occupational computer use were factors affecting severity.

Conclusion

Self-treatment with press needles for chronic neck pain did not significantly reduce the VAS score compared to placebo but reduced the motion-related pain as assessed by M-VAS score. A direct association was observed between pain severity and the effectiveness of press needles, and the impact of age and computer were indirectly linked by pain severity.

Clinical Trial Registration

Identifier UMIN-CTR, UMIN000044078.
QTL identified that influence tuber length–width ratio, degree of flatness, tuber size, and specific gravity in a russet-skinned, tetraploid mapping population
Authors: Park Jaebum , Whitworth Jonathan , Novy Richard G.
Published: March 2024

Potato tuber shape, size, and specific gravity are important agronomic traits in the russet market class of potatoes with an impact on quality, consistency, and product recovery of processed foods such as French fries. Therefore, identifying genetic regions associated with the three traits through quantitative trait locus/loci (QTL) analysis is a crucial process in the subsequent development of marker-assisted selection for use in potato breeding programs. QTL analysis was conducted on a tetraploid mapping population consisting of 190 individuals derived from the cross between two russet-skinned parents, Palisade Russet and the breeding clone ND028673B-2Russ. Field data collected over a 2-year period and used in the QTL analyses included tuber length–width and width–depth ratios that were obtained using a digital caliper. The width–depth ratio provided an assessment of the “flatness” of a tuber, which is of importance in potato processing. To cross-validate the accuracy and differences among tuber shape measurement methods, a trained evaluator also assessed the identical tubers based on 1–5 scale (compressed to long) visual assessment method. Furthermore, the weights of analyzed tubers and specific gravities were also collected during the phenotyping process for each mapping clone. A major tuber shape QTL was consistently observed on chromosome 10 with both the length–width ratio and visual assessments. On chromosome 4, a significant QTL for tuber shape from the visual assessment phenotypic data was also detected. Additionally, a tuber shape-related QTL on chromosome 6 was also detected from the length–width ratio data from 2020. Chromosome 2 was also identified as having a significant QTL for the width–depth ratio, which is of importance in influencing the flatness of a tuber. One significant QTL for tuber weight (i.e., tuber size) was observed on chromosome 5, and a significant QTL for specific gravity was found on chromosome 3. These significant and major QTL should be useful for developing marker-assisted selection for more efficient potato breeding.
How training quality, trainer competence, and satisfaction with training affect vocational identification of apprentices in vocational education programs
Authors: Wuttke Eveline , Heinrichs Karin , Koegler Kristina , Just Andreas
Published: March 2024

Vocational identification means being identified with an organization and with one’s career. Both are key objectives of vocational education and training (VET) programs and advantageous for employees and employers. For employees, vocational identification is often associated with positive work-related emotions and job satisfaction; for employers, workers’ identification with the organization and the career enhances their performance and reduces turnover. Thus, investment in employees’ professional development that has the potential to support vocational identification is advantageous for all involved. In light of current demographic changes and a decreasing demand for full-time work, which are leading to a shortage of skilled workers and lower enrolment in apprenticeship programs, it is essential to bind young talents to companies at an early stage and avoid resignations during or after training. Findings from various empirical studies confirm that those who identify with their chosen career and the organization for which they work are more satisfied, think less about quitting, and perform better. Little empirical research has been conducted on how apprentices in VET programs identify with their career or organization or the extent to which such identification enhances their job satisfaction. In this study, we therefore investigate factors that influence apprentices’ identification with their career and organization, in particular, the effects of training quality and trainer competence. Our results indicate that apprentices identify strongly with their career and with the organization where they are doing their training and are mostly satisfied with the quality of their training. Structural equation modeling reveals the relevance of career choice, training quality, and job satisfaction for identification with an organization and (less) with a career. The learning and working conditions in the organization, and more specifically, the variety of tasks offered to the apprentices and the trainer’s pedagogical aptitude explain satisfaction with the training and career identification; the trainer’s presence and the apprentices’ satisfaction with training explain, to some degree, variance in organizational identification.
The mediating role of social media addiction and phubbing in basic psychological needs in relationships and relationship satisfaction
Authors: Karaman Hüseyin Buğra , Arslan Coşkun
Published: March 2024

This study aimed to examine the mediating role of phubbing and social media addiction in the correlation between satisfaction levels of basic psychological needs in romantic relationships and relationship satisfaction. The participants were 958 students from various universities in Türkiye. The research utilized demographic information form for personal information of the participants, the Satisfaction of Basic Psychological Needs in Romantic Relationships Scale, the Generic Scale of Phubbing, the Social Media Addiction Scale-Adult Form, and the Relationship Satisfaction Scale. It was concluded in the research that social media addiction and phubbing had a mediating role in the correlation between the needs for love/belonging β = 0.05, power β = 0.03, and freedom β = −0.08 and the relationship satisfaction. The bootstrapping method performed in the study showed that indirect effect of the need for fun on the relationship satisfaction was significant, but in the Sobel test, social media addiction and phubbing was not found to have a mediating role in this correlation (p > 0.05). It was concluded that phubbing had a mediating role for all needs other than the need for fun in the correlation between satisfaction of basic psychological needs in romantic relationships and social media addiction. Finally, social media addiction was found to have a mediating role in the correlation between phubbing and relationship satisfaction. These findings were discussed in line with the literature. As shown by the findings, it was observed that satisfaction of basic psychological needs in romantic relationships affected the relationship satisfaction, and social media addiction and phubbing had a mediating role in that correlation.
Persisting inhibition biases efficient rule inference under uncertainty
Authors: Zivi Pierpaolo , Zigrino Anna , Couyoumdjian Alessandro , Ferlazzo Fabio , Sdoia Stefano
Published: March 2024

Introduction

Task set inhibition supports optimal switching among tasks by actively suppressing the interference from recently executed competing task sets. It is typically studied in cued task-switching paradigms where there is no uncertainty about the task set or rule to prepare for on each trial. While inhibition has been shown to influence the speed and the accuracy of task execution, affecting task set retrieval, preparation, or implementation in conditions of task set switching, it remains uninvestigated whether it also affects rule selection under uncertainty.

Methods

We implemented an ad-hoc four-rule card sorting task and categorized the rules selected by participants after a rule shift according to the recency of their last usage. We included a measure of working memory capacity (WMC) to control for its involvement in the rule selection process.

Results

Participants exhibited a reduced preference for recently abandoned rules than less recently abandoned ones. Furthermore, we found that such a preference was not associated with WMC.

Discussion

The results suggest that decision-making processes underlying rule inference and selection may be influenced by task-set inhibition, configuring as a conflict adjustment mechanism to the sequential history of rules application.
Hypnosis in psychotherapy, psychosomatics and medicine. A brief overview
Authors: Peter Burkhard
Published: March 2024

Aspects of hypnosis and its application in psychotherapy, psychosomatics and medicine are examined and contextualized in the 250-year history of hypnosis. Imagination as an essential element of hypnotic treatments appeared as early as 1784 as an argument rejecting the theory of animal magnetism of Franz Anton Mesmer. In somnambulism of German romanticism, another proto-form of hypnosis after 1800, concepts of the mind–body problem were dealt with, which still characterize the understanding of unconscious mental processes today. Hypnosis was at the beginning of psychoanalysis, but was not pursued further by Sigmund Freud from 1900 onwards. Nevertheless, there were some hypnoanalytical approaches in the 20th century, as well as attempts to integrate hypnosis into behavior therapy. Techniques of imagination and relaxation combine both; in particular findings from cognitive psychology explain processes of both hypnosis and cognitive behavioral therapy. The influence of social psychology brought a new perspective to the debate about the nature of hypnosis, which continues to this day: is hypnosis to be understood as a special state of consciousness or is it a completely normal, mundane interaction? The experiments that were carried out to support one side or the other were also dependent on the hypnotizability of the subjects involved, as the more difficult hypnotic phenomena such as paralysis, hallucinations or identity delusions can only be demonstrated by highly hypnotizable subjects. The fact that these are not mere compliance reactions has now been proven by many studies using imaging techniques. But even those who are moderately hypnotizable benefit from hypnosis rituals. Variables postulated by socio-cognitive hypnosis researchers, such as motivation and expectation, are relevant, as is a good “hypnotic rapport.” Practical application of hypnotherapy today is characterized by the innovative techniques and strategies developed by Milton H. Erickson. Research into the effectiveness of hypnosis in the field of psychotherapy and psychosomatics still leaves much to be done. The situation is different in the field of medical hypnosis, where there are considerably more studies with a satisfactory design and verifiable effects. However, the impact in practical application in everyday medical practice is still low. Newer developments such as virtual reality and artificial intelligence are being looked at with critical interest.
Does coping style mediate the relationship between knowledge and psychosocial outcomes in women with atrial fibrillation?
Authors: Le Grande Michael R. , Salvacion Marielle , Shwaita Lubab , Murphy Barbara M. , Jackson Alun C. , Alvarenga Marlies E.
Published: March 2024

Introduction

In patients affected by atrial fibrillation (AF) disease-specific knowledge and coping style may be associated with psychosocial well-being. This study aimed to determine if coping style (problem-focused, emotion-focused, avoidance-focused) mediated the relationship between patient knowledge and three psychosocial outcomes (anxiety, depression and life satisfaction).

Methods

In 2021 a total of 188 women with reported AF, and ages ranging from 18 to 83 years (mean 48.7, sd 15.5 years), completed an online questionnaire consisting of sociodemographic, clinical and AF knowledge questions and psychosocial instruments (Anxiety and depression, the Hospital Anxiety and Depression (HADS) scale; life satisfaction, Satisfaction With Life Scale (SWLS); and coping style (Brief COPE). Using Jamovi statistical software three individual mediational models (for anxiety, depression and life satisfaction) were constructed assessing the direct and indirect relationships between knowledge, coping style and each psychosocial outcome. Age was a covariate in each model.

Results

The mediation analyses demonstrated significant direct negative associations between AF knowledge and HADS anxiety and depression and positive associations with SWLS. There were also direct associations between each of the three coping styles and the three psychosocial outcomes. There were significant indirect effects of coping style between AF knowledge and each of the three outcomes confirming partial mediation effects.

Discussion

These findings highlight the crucial role of coping style in mediating the association between AF knowledge and psychosocial outcomes. As such, interventions aimed at increasing patient knowledge of AF may be more effective if adaptive problem-solving coping strategies are also demonstrated to these patients. Additionally, modification of maladaptive coping strategies as part of the psychological management of patients with AF is highly recommended.
Caregiving consequences in cancer family caregivers: a narrative review of qualitative studies
Authors: Rezaei Masoud , Keyvanloo Shahrestanaki Sahar , Mohammadzadeh Razieh , Aghili Mohammad Sadegh , Rajabi MohammadReza , Abbasi Mohammad , Khachian Alice , Momen Reza , Khavassi Mohammad , Aghaei Simin
Published: March 2024

Background

Cancer is a significant public health issue, causing various challenges for individuals affected by it. As cancer progresses, patients often become dependent on others for support. Family caregivers and members play a crucial role in the recovery and rehabilitation of these patients. However, caregivers themselves face numerous challenges throughout the course of their family member’s illness. Exploring the experiences of family caregivers can inform long-term planning and supportive interventions to address their caregiving difficulties. This study reviews previous literature on caregiving outcomes.

Method

This study presents a narrative review of qualitative studies, analyzing a total of 23 articles. The results were extracted and organized into subcategories. After revision by the research team, main categories were identified. These categories encompass both positive and negative outcomes of caregiving.

Results

The findings of this review demonstrate that caring for a family member with cancer has significant implications for caregivers. These implications include: (A) Positive outcomes of caregiving (such as achieving self-management and balance, promoting kinship intimacy, finding meaning and purpose, and experiencing spiritual growth) and (B) Negative outcomes of caregiving (including care-related physical exhaustion, disruption of personal life plans, psycho-emotional consequences, and socio-economic burden).

Conclusion

The results of this study highlight the challenges faced by family caregivers and emphasize the importance of addressing their needs within the healthcare system. By providing support and attention to their well-being, caregivers can enhance their resilience and adaptability in managing caregiving difficulties.
Endocrine disrupting chemical Bisphenol A and its association with cancer mortality: a prospective cohort study of NHANES
Authors: Yuan Ying , Chen Qian , Ding Xiaorong , Zhong Qin , Zhong Xiaomin
Published: March 2024

Introduction

There is evidence suggesting that Bisphenol A (BPA) is associated with increased all-cause mortality in adults. However, the specific nature of the relationship between BPA exposure and cancer mortality remains relatively unexplored.

Methods

The National Health and Nutrition Examination Survey (NHANES) dataset was used to recruit participants. Urinary BPA was assessed using liquid chromatography-mass spectrum (LC–MS). Through the use of multivariable Cox proportional hazard regressions and constrained cubic splines, the relationships between urine BPA and death from all causes and cancer were investigated.

Results

This study has a total of 8,035 participants, and 137 died from cancers after a 7.5-year follow-up. The median level of BPA was 2.0 g/mL. Urinary BPA levels were not independently associated with all-cause mortality. For cancer mortality, the second quartile’s multivariable-adjusted hazard ratio was 0.51 (95% confidence interval: 0.30 to 0.86; p = 0.011) compared to the lowest quartile. The restricted cubic splines showed that the association was nonlinear (p for nonlinearity = 0.028) and the inflection point was 1.99 ng/mL.

Conclusion

Urinary BPA exposure was U-shaped associated with the risk of cancer mortality, and a lower level of BPA less than 1.99 ng/mL was associated with a higher risk of cancer mortality.
Development and experiences of an internet-based acceptance and commitment training (I-ACT) intervention in ice hockey players: a qualitative feasibility study
Authors: Reinebo Gustaf , Björverud Linda G. , Parling Thomas , Andersson Gerhard , Jansson-Fröjmark Markus , Lundgren Tobias
Published: March 2024

Internet-based psychological interventions have increased the accessibility of evidence-based treatments in clinical psychology but are still an unexplored delivery format in sport psychology research. This study describes the development and evaluates the experiences of an internet-based acceptance and commitment therapy/training (I-ACT) intervention in ice hockey players focusing on performance enhancement and a sustainable sport participation. I-ACT consisted of seven weekly modules and the feasibility of the intervention was investigated using a qualitative research design. Four national level ice hockey players took part of I-ACT and were interviewed about their experiences using a semi-structured protocol. Interview transcripts were analyzed using qualitative content analysis. Findings suggest that the content of I-ACT was comprehensible, relevant, and that it was possible to put the psychological skills into practice. I-ACT was described as helpful to the ice hockey players either in their sport performance or in their life outside of sport. The internet-format was generally perceived as positive, flexible, and a feasible option for delivering psychological interventions in an elite sport context. Some concerns were raised regarding the timing of the intervention at the end of the season, and some players also wished for more time to complete I-ACT. It was also expressed that some of the exercises could have been better adapted for goaltenders. Further trials are needed to evaluate the effects of I-ACT on performance and mental health outcomes in various sport populations using robust quantitative research methodology. Internet-based psychological interventions are a potential future opportunity to make evidence-based practices more accessible for athletes.