bluuebunny/crossref_metadata_2025 huggingface dataset:
PRÁTICAS INTEGRATIVAS E COMPLEMENTARES PARA REALIZAÇÃO DA CITOLOGIA ONCÓTICA NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Silva Maiara Fabiany Dantas , Silva de Araújo Maria Eduarda , Araújo Juliana Iscarlaty Freire de , Oliveira Renata Cardoso , Araújo Mércio Gabriel de , Bezerra Héllyda de Souza
Published: January 2025

O câncer de colo uterino apresenta elevados índices de morbidade e mortalidade em todo o mundo. O exame Papanicolau é responsável por cerca de 80% da detecção precoce do câncer, porém existe uma baixa adesão ao exame, relacionada a fatores culturais, sociais, psicológicos e econômicos que afetam a detecção em tempo oportuno e a redução da mortalidade por esse câncer. O objetivo deste estudo é analisar o uso da musicoterapia e aromaterapia na realização da citologia oncótica para as mulheres. Trata-se de um estudo descritivo, de caráter exploratório e abordagem qualitativa, realizado em um município do interior do Rio Grande do Norte, entre os meses de julho e outubro de 2023. A faixa etária incluída foram mulheres de 18 a 64 anos, sendo a amostra constituída por 15 mulheres. A coleta de dados se deu pela técnica de questionário semiestruturado. As informações obtidas foram analisadas por conteúdo, segundo Bardin. Participaram do estudo 15 mulheres, com idades entre 21 e 63 anos. Os resultados da pesquisa estão dispostos em duas categorias: sentimentos das mulheres relacionados à realização do exame preventivo; percepção das participantes sobre a coleta com utilização das Práticas Integrativas e Complementares utilizadas no estudo. As participantes, mesmo sabendo da importância de realizar o exame periodicamente, por diversos fatores, não realizam conforme preconizado. Sentimentos como vergonha e tensão são fatores que influenciam na adesão ao exame preventivo e interferem na procura pelos serviços. Portanto, a utilização das Práticas Integrativas e Complementares são eficazes quando objetivam construir um atendimento humanizado e formação de vínculo entre profissional e paciente.
MÉTODOS, FERRAMENTAS E APLICAÇÕES DA METANÁLISE EM REVISÕES
Authors: Sales Weslley Barbosa , Costa Laura Beatriz Alves , Guilherme Mateus dos Santos de Albuquerque , França Dimas Cícero Martins de , Silveira Francisco Romário , Silva Mateus Osório da
Published: January 2025

Este estudo tem como objetivo investigar e elucidar os métodos, técnicas e aplicações da meta-análise em revisões sistemáticas, fornecendo uma compreensão abrangente do processo de seleção de estudos, extração de dados, cálculo de tamanhos de efeito, estimativa de modelos e exploração de viés de publicação. Trata-se de uma revisão sistemática, orientada pelas diretrizes do PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis). As bases de dados utilizadas incluem PubMed/MEDLINE, Scopus, Web of Science, PsycINFO, Google Scholar e LILACS (Literatura Latino-Americana e do Caribe em Ciências da Saúde). As palavras-chave foram selecionadas a partir do DeCS (Descritores em Ciências da Saúde), sendo "Revisão Sistemática" e "Meta-Análise." Foram incluídas revisões de qualquer tipo (narrativas, integrativas, sistemáticas com ou sem metanálise) e estudos publicados na íntegra, sem restrições de data ou idioma, que explorassem as diversas aplicações da metanálise e fornecessem orientações para interpretar e apresentar seus resultados com precisão. Excluíram-se artigos experimentais, estudos observacionais, cartas editoriais, preprints, artigos publicados apenas em anais de congressos e artigos sem resumos ou indisponíveis online. As buscas nas bases de dados selecionadas ocorreram entre janeiro e junho de 2024, identificando um total de 130.588 artigos. Após a etapa de identificação, foi realizada a análise de duplicatas, resultando na exclusão de 45.856 artigos duplicados. Após essa triagem, 84.732 foram elegíveis para leitura de títulos e resumos. Nessa etapa, se excluiu 65.126 ensaios clínicos e estudos experimentais, além de 19.400 estudos observacionais, restando um total de 206 artigos para leitura do material na íntegra. Destes, apenas 10 foram considerados elegíveis para a amostragem final do artigo. A metanálise surge como uma ferramenta essencial para a síntese de dados em revisões sistemáticas, oferecendo uma visão abrangente e robusta dos resultados.
In vivo reparative regeneration of skin using a cream based on silk proteins: spidroin, fibroin, and sericin
Authors: Sorochanu Irina P. , Blitzine Kristina S. , Daudi Dauddin I. , Zhemkov Nikita I. , Pechenina Alina A. , Dmitrieva Maria A. , Grin Nikita A. , Asatryan Tatevik T. , Tatarkin Vladislav V. , Trunin Evgeniy M. , Deev Roman V.
Published: January 2025

BACKGROUND: Disruption of the stages of reparative regeneration leads to insufficient formation of the extracellular matrix and the development of chronic wounds, which require a personalized therapeutic approach. Modern regenerative medicine utilizes biopolymers, such as silk proteins, as the basis for wound dressings and drug delivery systems, which possess a number of unique properties. The biocompatibility, influence on intracellular signaling pathways, and antibacterial activity of spidroin (spider silk protein), fibroin, and sericin (the basis of insect silk) make them potentially applicable as wound healing agents.
AIM: The aim of the study is to characterize the effect of a cream based on a solution of silk spidroin, fibroin, and sericin proteins on skin regeneration in a comparative experiment.
MATERIALS AND METHODS: The study was conducted on 30 male rats with surgically created full-thickness excisional skin defects measuring 20 mm in diameter on their backs. The rats were then divided into three groups: group 1 received daily topical application of the investigated cream, group 2 received a commercial panthenol product, group 3 served as the control group, with wounds left to heal spontaneously. The process of reparative regeneration and reactive changes were assessed through clinical blood analysis, planimetric measurements of wound closure, and histomorphometric analysis of tissue samples.
RESULTS: The treatment group exhibited a positive trend in wound healing (p=0.010) with faster complete skin closure (by day 14) compared to the control group. Evaluation of the inflammatory response revealed no significant changes in blood parameters (moderate granulocytosis and signs of acute posthemorrhagic anemia) and reduced immune cell infiltration compared to the control group.
CONCLUSION: The combination of spider silk proteins (spidroin) and insect silk proteins (fibroin and sericin) has the potential to enhance cell migration, proliferation, and differentiation, as well as extracellular matrix production. They also exhibit anti-inflammatory activity without possessing immunogenic properties. These characteristics provide a basis for the potential use of these proteins as standalone therapeutic agents, including in the clinical management of wounds with impaired healing.
Indication of Fluid-Driven Seismicity in the Palghar Region, India, from Local Earthquake Tomography
Authors: Kanaujia Jyotima , Kumar Mangalampally Ravi , Vengala Pavan Kumar , Shekar Mandadi
Published: January 2025

The Palghar region in western India has recently witnessed intense seismicity, categorized as swarm activity in an intraplate setting. Numerous studies have been hitherto conducted to interrogate the causative mechanisms for this nonvolcanic tremor. In this study, we present the seismic crustal velocity structure of the source region using travel times of 32,921 P and 31,452 S phases picked from waveforms of 8359 events recorded by a six-station seismological network of the Council of Scientific and Industrial Research-National Geophysical Research Institute, installed to closely monitor this activity. The tomographic sections reveal presence of low shear velocity and high VP/VS anomalies in the swarm area, indicative of fluids in the upper crust down to 15 km. Drawing support from the low-resistive zone inferred from inversion of magnetotelluric data, we emphasize the role of crustal fluids in the genesis of such swarms.
Importance of Considering Near-Surface Attenuation in Earthquake Source Parameter Estimation: Insights from Kappa at a Dense Array in Oklahoma
Authors: Chang Hilary , Abercrombie Rachel E. , Nakata Nori
Published: January 2025

Separating earthquake source spectra from propagation effects is challenging. The propagation effect contains a site-dependent term related to the high attenuation of shallow sediments. Neglecting the site-dependent attenuation can cause large biases and scattering in the corner-frequency (fc) estimates, resulting in significant stress-drop deviations. In this study, we investigate shallow attenuation at the LArge-n Seismic Survey in Oklahoma (LASSO) and site-related biases and scattering in source parameter measurements due to simplified attenuation models. We measure the high-frequency spectral decay parameter kappa on the vertical acceleration spectra of regional earthquakes (125 km away). The site-dependent kappa (κ0,acc) suggests that attenuation increases rapidly at shallow depth and is highly site-dependent. 10%–75% of the attenuation is site-dependent for S waves and even larger for P waves. The quality factor for S waves (QS) ranges from 10 to 100 in the upper 400 m. QP for P waves is mostly below 10 within the same depth. The Quaternary sediments tend to be more attenuating (QS<30), but the Permian rocks also can have high attenuation. We demonstrate that using a non-site-dependent attenuation model in single-spectra fitting leads to large scattering in fc estimates among stations with apparent good fits. The apparent fc can significantly deviate when the range of site-dependent kappa is large or with a higher assumed source spectral fall-off rate n. The biases in apparent fc depend on site condition and distance; however, the correlation between fc and these factors might not be obvious, depending on model assumptions. An apparent increase of stress drop with magnitude in a previous study for local microearthquakes (1.3<Mw<3.0) can be largely negated by including a site term, restricting to sites on the higher Q formations, and fixing n. This study highlights the importance of considering near-surface attenuation when modeling source parameters.
Does Subsurface Fault Geometry Affect Aleatory Variability in Modeled Strike-Slip Fault Behavior?
Authors: Zielke Olaf , Mai P. Martin
Published: January 2025

The nonplanar geometry of faults influences their seismotectonic behavior, affecting the initiation, propagation, and termination of individual earthquakes as well as the stress–slip relationship and probability of multisegment rupture. Consequently, computer simulations that aim to resolve the earthquake rupture process and make predictions about a fault’s future behavior should incorporate nonplanar fault geometries. Although surface traces of faults can be mapped with high accuracy, a key challenge is to define a fault’s detailed subsurface geometry due to a general lack of data. This raises the question of which geometry to use. Does it matter which subsurface geometry is utilized in earthquake rupture simulations, as long as at least the fault trace is considered? How different is the simulated fault behavior for faults that share the same surface trace but different subsurface geometries? Using the physics-based earthquake-cycle simulator MCQsim, we generate seismic catalogs for 100 × 20 km strike-slip faults, assuming variations in fault surface trace, subsurface geometry, and strength distribution. We investigate how the long-term fault behavior—in the form of magnitude–frequency distribution, earthquake interevent time, and maximum earthquake size—is affected by fault geometry and strength distribution. We find that the simulated behavior of strike-slip faults with identical fault traces is interchangeable—even if their subsurface fault geometries differ. Implementing the fault trace constrains possible fault geometries to a level that makes the long-term behavior indistinguishable—at least for strike-slip faults with “known” strength distribution and length-to-width aspect ratios that are equal or larger than what we used here. The fault trace can provide a satisfactory representation of subsurface geometry for assessing long-term fault behavior.
Barriers to Innovation Activity of Enterprises and Their Determinants
Authors: Podstawka Beata , Kijek Tomasz , Matras-Bolibok Anna
Published: January 2025

Theoretical background: Innovation is essential for enterprise development and economic growth. Therefore, knowing and characterising the determinants of innovation activity in enterprises is crucial. Determining the factors that shape the innovativeness of enterprises will enable entrepreneurs to skillfully and flexibly adapt to both the current and future market situation. Innovation is a process that involves significant expenses, a long payback period, specific risks and uncertainty, as companies are exposed to various obstacles, both internal and external, throughout the innovation process. Factors limiting innovation implementation are perceived differently by companies of different sizes, ages or depending on the scale of their operations. The literature provides many classifications and divisions of barriers to innovation activity, butthere is still little research on the factors influencing their perception.

Purpose of the article: The study aims to identify the factors hindering the decision to start or carry out innovative activity and the determinants of a firms’ perception of barriers to innovation activity in enterprises from the Lubelskie Voivodship in 2017–2019.

Research methods: A questionnaire survey on a research sample of 104 enterprises from the Lubelskie Voivodship was conducted, and exploratory factor analysis was employed.

Main findings: The paper identifies the most important factors hindering the decision to start or carry out innovative activity in enterprises from the Lubelskie Voivodship in 2017–2019. On the basis of the results of surveys and exploratory factor analysis, it was found that an important barrier to carrying out innovative activity of entities in the Lubelskie Voivodship is the financial barrier related to the lack of capital, difficult access to it and high cost of its service, as well as high costs of innovative activity. In the opinion of entrepreneurs, the market situation, i.e. uncertain demand for new ideas and too much competition in the market and internal processes, are important factors for the development of innovation. The analysis also demonstrates that the sector and scale of activity impact the perception of barriers to innovation. For companies operating in the service sector, the constraints to innovation processes related to the financial, market and internal processes are lower than in the group of industrial and construction companies. The results also indicate a negative relation between the scale of activity and innovation obstacles related to internal processes.
Work-Life Balance and the Individuals’ Labour Supply
Authors: Stepanok Nina
Published: January 2025

Theoretical background: In the turbulent conditions of today’s world, individuals seek stability and harmony, making the problem of work-life balance particularly vital. The issue of work-life balance is at the intersection of economic behaviour and the emotional state of the individual. Each component of the work-life system is fundamentally important for individuals, but the desire for a high level of consumption and ensuring financial security may push them to skew the balance in favour of work. However, a higher level of wages could provide sufficient levels of consumption for individuals and return to the desired work-life balance through the choice of free time for non-work activities.

Purpose of the article: The purpose of this article is to investigate the labour supply of individuals that seek to maintain a life-work balance.

Research methods: A model was constructed and analyzed in order to find the optimal labor supply of an individual, taking into account time free from work. As part of the study, a survey was also conducted among 200 individuals in Poland in 2024, which revealed some personal and psychological aspects regarding work-life balance among the respondents.

Main findings: The analysis of the constructed model, as well as the survey conducted among individuals, proves that the higher the wage level, the more individuals are willing to supply their labour. With the need to maintain individuals’ work-life balance, the motivational function of wages remains crucial. The results also show that individuals with alternative sources of income have more opportunities to maintain a work-life balance.
Financing Family Businesses Through Private Equity
Authors: Węcławski Jerzy
Published: January 2025

Research background: Private equity is used to finance family businesses in different forms and stages of the development cycle. The immanent characteristics of family businesses, which are the desire to maintain economic independence and to carry out succession, are at odds with the nature of private equity investment, which involves taking equity stakes and controlling the business.

Purpose of the article: The study aims to identify the adaptation of private equity financing to the nature of family businesses and to indicate in which situations it can be used.

Research methods: The paper draws on research results presented in the literature, reports, and results from the author’s own research.

Main findings: The results of the analyses carried out indicate that financing by means of private equity is relatively rarely used by family businesses in both the European market and in Poland, but at the same time, they indicate situations where it is appropriate or necessary.
How Much Is WIRON Better Than WIBOR?
Authors: Karwowski Jacek
Published: January 2025

Theoretical background: The transition from traditional interbank offered rates (IBORs) to more stable and reliable benchmark rates has become a focal point in the financial industry, particularly in the aftermath of the LIBOR scandal. We endeavour to apply theoretical considerations regarding proper benchmark rates within the context of WIBOR and WIRON rates on the Polish financial market. This study delves into the characteristics and effectiveness of both rates.

Purpose of the article: The purpose of this research is to evaluate WIRON against WIBOR across several key dimensions to determine which rate serves as a better benchmark for financial instruments in Poland. This com-parison is pivotal, as the chosen benchmark rate significantly impacts the valuation, risk, and performance of a wide array of financial products and contracts. It is hypothesized that WIRON fulfils more criteria of ideal refer-ence rate than WIBOR.

Research methods: Our methodology integrates a comprehensive qualitative and quantitative analysis, comparing WIBOR and WIRON against established criteria for a proper reference rate. This includes an examination of their verifiability, susceptibility to manipulation, daily calculation, independence from policy rates, resilience to market stress, avoidance of calendar effects, and representativeness of the underlying market. To delve deeper into the quantitative aspect, we will conduct numerical analysis and a comparison of quotations employing standard statistical indicators, as well as utilizing the Generalized Autoregressive Conditional Heteroskedasticity (GARCH) model.

Main findings: The findings indicate that WIRON potentially offers a more robust alternative to WIBOR, par-ticularly for overnight (ON) tenors. WIRON demonstrates a slightly better alignment with the principles of veri-fiability, resilience, and representativeness, attributed to its design that leverages actual transaction data. How-ever, both rates adequately meet the majority of the proper reference rate criteria, with unique advantages in different contexts. The study also observes that WIRON, while advantageous in specific aspects, does not deci-sively outperform WIBOR across all tenors and criteria. It particularly concerns the fact that WIBOR rates are an outcome of a market-based price formation process; they embed market participants’ expectations about future interest rates and market conditions. This nuanced evaluation underscores the complexity of selecting a singular benchmark rate that can effectively cater to the diverse needs of the financial market.
Price Information Overload as an Indirect Consequence of Omnibus Directive Implementation – a Theoretical Approach to PIO
Authors: Lipowska Ilona
Published: January 2025

Theoretical background: Information overload (IO) occurs when information flow exceeds the information needs. Nowadays IO is perceived as a permanent feature of modern society. Undoubtedly, IO is a negative phenomenon due to its negative impact on consumer behaviour. Price information overload (PIO) is a specific type of IO. PIO is a phenomenon that can arise due to a change in EU law. The Omnibus Directive, implemented in Poland as an EU member state, has created a new requirement for sellers to communicate promotional prices. This requirement includes the lowest price in force 30 days before introducing the price reduction (known as the omnibus price). PIO occurs when there is an excess of mandatory promotional price information provided to the buyer.

Purpose of the article: This article attempts to introduce the concept of price information overload, which has not been previously discussed in the marketing literature to the best of the author’s knowledge. The paper also highlights the indirect consequences of implementing the Omnibus Directive in an EU member state.

Research methods: This article introduces a new type of information overload called “price information overload” (PIO) and extends the concept of information overload (IO). The article is a theoretical paper that presents PIO’s essence and some graphical representations. The author, who specializes in pricing, developed the PIO concept by starting with the scientific literature on IO.

Main findings: The author posits that the Omnibus Directive does not inherently pose a risk of PIO, but rather that sellers may inadvertently contribute to it through their pricing practices. The PIO concept highlights the relevance and actuality of the IO issue in communicating promotional prices. The idea of being overwhelmed with too much price information is a practical concern. Consequently, the author suggests that a potential deluge of price information be regarded as an element of a nuanced system of price communication.
Main Directions of Changes in Road Transport of Goods in Poland
Authors: Gajewski Radosław
Published: January 2025

Theoretical background: Road transport is the key type of transport in Poland in terms of servicing the domestic and international market. Since Poland entered the European Union, there has been a systematic, spatially diverse increase in the number of transport companies.

Purpose of the article: The aim of the article is to analyze the main changes that are occurring in Polish road transport based on the data of the Central Statistical Office in Warsaw from 2004–2023. Particular emphasis has been placed on the comprehensive coverage of the changes that have occurred in the recent period in the road transport sector in Poland. Attention was paid to the issue of green transformation of the road transport sector and the use of alternative fuels.

Research methods: The study used basic statistical methods to analyze the structure and dynamics of changes that occurred in the road transport sector in Poland during the period under study. Regression analysis was carried out to determine the directions of the changes taking place. The analyses were based on official databases and data published by the Central Statistical Office. The comprehensive scope of the analysis included the use of data covering trucks by load capacity, vehicle age, type of fuel used, cargo transport, number of employees and turnover. The study also used data on transportation in export and import operations.

Main findings: The results of the study demonstrate that road transport in Poland is strongly dependent on international export and import operations directed primarily towards Germany. The existing fleet of trucks uses primarily diesel fuel, which indicates a huge potential for investment in alternative fuel sources. Mazovian and Greater Poland voivodeships (provinces) play a leading role in road transport in terms of the number of tractor units, as their territories are intersected by Pan-European Corridor II.
Model Project Based Learning dalam Pembelajaran Seni Rupa untuk Meningkatkan Kreativitas Siswa Kelas VIII SMP
Authors: Gusti Getar Pramustya , Rahayuningtyas Wida
Published: January 2025

Kreativitas adalah membuat suatu hal unik yang belum pernah terpikirkan oleh orang lain. Penyebab kurangnya kreativitas pada peserta didik yaitu rendahnya kepercayaan diri mempresentasikan ide saat pembelajaran belangsung. Model Project Based Learning (PjBl) adalah suatu bentuk pembelajaran yang tidak hanya menekankan pada penguasaan konsep materi saja, tetapi juga melaksanakan pada peran pengetahuan dan teknologi di dalam berbagai kehidupan masyarakat dan menumbuhkan rasa tanggung jawab sosial terhadap dampak sains yang terjadi di masyarakat. Penelitian ini bertujuan meningkakan kualitivitas peserta didik dalam pembelajaran seni budaya mater seni rupa apresiasi ragam hias tradisional nusantara di kelas VIII E SMPN 9 Malang. Jenis penelitian yang dilakukan adalah Penelitian Tindakan kelas (PTK) mengacu model Kemmis & Mc Taggart dengan dua siklus, setiap siklus memiliki empat tahapan yaitu perencanaan, pengamatan, pelaksanaan dan refleksi. Hasil dari dua siklus yang telah dilaksanakan, penerapan pendekatan model pembelajaran Project based learning pada mata pelajaran seni budaya (seni rupa) berhasil meningkatkan kreatifitas peserta didik dalam berproses menggambar ragam hias tradisional nusantara dengan menggunakan stimulus yang telah dikembangkan.
Pengembangan Media Ular Tangga untuk Meningkatkan Motivasi Belajar Siswa Kelas VIII SMP
Authors: Safitri Ananda Putri , Soelistijo Djoko
Published: January 2025

Pemanfaaatan media pembelajaran yang kurang variatif akan menyebabkan penurunan motivasi belajar siswa. Jika diabaikan, hal ini akan berpengaruh terhadap kurangnya pemahaman siswa terhadap materi yang dipelajari. Tujuan penelitian ini yakni untuk mengembangkan media ular tangga guna meningkatkan motivasi belajar siswa kelas VIII. Metode yang dipakai untuk mencari jawaban dari tujuan penelitian yakni penelitian pengembangan model ADDIE meliputi analysis, design, development, implementation, dan evaluation. Data penelitian mencakup lembar observasi dan angket dengan analisis deskriptif. Implementasi media ular tangga diterapkan sekali pada subjek penelitian kelas VIII SMP Negeri 28 Malang dengan melibatkan 20 siswa. Hasil penelitian menunjukkan bahwa media ular tangga layak untuk dimanfaatkan guru sebagai media pembelajaran karena dapat meningkatkan motivasi belajar siswa baik pada indikator semangat belajar, keaktifan, maupun ketertarikan. Peneliti selanjutnya direkomendasikan untuk mengembangkan pertanyaan dan jawaban yang dekat dengan lingkungan siswa sesuai dengan materi ajar sehingga dapat dipakai untuk kelengkapan kartu soal dan jawaban pada komponen media ular tangga.
Implementasi Model Pembelajaran Project Based Learning dalam Meningkatkan Hasil Belajar Bahasa Indonesia pada Siswa Kelas 1 SD
Authors: Rofiqoh Hefi Yuli Aida Nur , Winahyu Sri Estu
Published: January 2025

Penelitian ini bertujuan untuk mengkaji implementasi Model Pembelajaran Project Based Learning (PBL) dalam meningkatkan hasil belajar Bahasa Indonesia pada siswa kelas 1 di SDN Kiduldalem 2 Kota Malang. Fokus utama dari penelitian ini adalah untuk mengetahui sejauh mana penerapan PBL dapat meningkatkan keaktifan, semangat, dan partisipasi siswa dalam pembelajaran Bahasa Indonesia. Dengan menggunakan pendekatan kualitatif, penelitian ini mengamati bagaimana PBL dapat merangsang keterlibatan aktif siswa dalam proses belajar, serta pengaruhnya terhadap peningkatan pemahaman mereka dalam aspek linguistik, seperti membaca dan menulis. Melalui pengamatan langsung, wawancara, dan pengumpulan data dari kuesioner, peneliti mengevaluasi perkembangan siswa dalam mencapai kompetensi bahasa yang telah ditentukan dalam kurikulum. Hasil penelitian diharapkan memberikan wawasan yang mendalam mengenai manfaat konkret penerapan PBL, khususnya dalam meningkatkan hasil belajar Bahasa Indonesia siswa kelas 1. Selain itu, penelitian ini juga diharapkan dapat memberikan dasar yang kuat bagi pengembangan metode pembelajaran inovatif yang dapat diterapkan di sekolah dasar, untuk menciptakan lingkungan belajar yang lebih aktif, kreatif, dan menyenangkan bagi siswa.
Endocarditis Bacteriana Aguda a S. gallolyticus asociada a neoplasia colónica
Authors: Escobar-Salinas Jorge Sebastián , Ferreira-Samudio Maria Leticia , Ortega-Filártiga Edgar Augusto
Published: January 2025

La endocarditis bacteriana por Streptococcus gallolyticus representa el 6% de los casos y se describe una asociación entre la bacteriemia a este germen y patologías colónicas, siendo el riesgo de portar una neoplasia de colón en pacientes con bacteriemia a este germen cinco veces mayor. Presentamos el caso de una mujer de 35 años, cardiópata y portadora de prótesis valvular aortica mecánica, anticoagulada, acude por un cuadro de 8 días de evolución de tos seca, pérdida de apetito y palidez de piel. 3 días antes del ingreso se agrega fiebre de 38,5° sin predominio de horario, acompañado de escalofríos que cedía parcialmente con antipiréticos y medios físicos. Acompaña al cuadro debilidad generalizada y dificultad respiratoria a moderados esfuerzos. Refiere cuadro similar hace 17 meses, con diagnóstico de endocarditis bacteriana aórtica a Streptococcus gallolyticus spp, que requirió reemplazo valvular aórtica con prótesis mecánica Se realiza una videocolonoscopia donde se observa un tumor vegetante a nivel del colon ascendente y cuya anatomía patológica informa un adenoma velloso con focos de adenocarcinoma intramucoso con márgenes libres. Conclusión: ante un caso de endocarditis a Streptococcus gallolyticus se sugiere realizar una colonoscopía a fin de descartar patología colónica por la asociación existente, y para los costos en salud por neoplasia colónica.
¿Qué percepción tiene el profesorado de la República Dominicana sobre las medidas de atención a la diversidad de su centro educativo? Un estudio de caso
Authors: Saviñón-Rodríguez Frank Dilio
Published: January 2025

La atención a la diversidad se refiere a la necesidad de adaptar la enseñanza y los recursos educativos para garantizar que todos los estudiantes, independientemente de sus diferencias en términos de habilidades, necesidades especiales, antecedentes culturales, género o cualquier otra característica, tengan igualdad de oportunidades para aprender y desarrollarse. El objetivo general del presente estudio es analizar la percepción del profesorado del Centro Educativo Federico García Godoy de la República Dominicana sobre la aplicación de las medidas de atención a la diversidad que se implementan en éste. Para ello, se recurrió a un diseño de investigación de corte cuantitativo y descriptivo tipo encuesta en el que participaron 40 docentes del centro educativo. Como técnicas de recogida de información se utilizó un cuestionario diseñado ad hoc, diseñado con cuatro valores de respuesta tipo Likert. Para el análisis de datos se recurrió a la estadística descriptiva obteniendo porcentajes y frecuencias. Los resultados muestran que las medidas de atención a la diversidad no solo se centran en aspectos académicos, sino que también incorporan el desarrollo de habilidades de vida, como la autonomía, la comunicación, la resolución de problemas y la toma de decisiones, que son esenciales para la vida cotidiana y la transición a la edad adulta. Se concluye que estas medidas no solo mejoran su rendimiento académico, sino que también los empoderan, fomentan la inclusión, preparando al alumnado para una vida plena y exitosa.
Age Differences in Mobile Technology Use Behavior and Perception During COVID-19
Authors: Lin Yi , Stromberg Arnold , Mankowski Robert , Smail Emily , Rowles Graham
Published: January 2025

Background and Objectives: COVID-19 led to quarantine and mandatory spatial distancing, making mobile technology critical in receiving information and services. Age differences were discovered in many aspects of mobile technology use; however, we lack knowledge about age differences in mobile technology use under the impact of COVID-19. Thus, this cross-sectional study investigated age differences in mobile technology use behavior and perceptions during COVID-19.

Research Design and Methods: We distributed a pilot-tested survey online. Participants were ≥35 years old, English speakers, and mobile technology users who lived in the United States. Data analysis involved descriptive statistics, Wilcoxon signed-rank test, and the Kruskal-Wallis test.

Results: Participants were categorized into three age groups, 35-49 (n=391, 45% female), 50-64 (n=435, 62% female), and ≥65 (n=386, 59% female). Each group significantly increased use frequency and perceived necessity to use mobile technology during COVID-19. People aged 35-49 reported using video/music entertainment more commonly than others, and people aged ≥65 reported more commonly using mobile technology for navigation and ordering taxi/car services during COVID-19 than those aged 35-49. We found no significant difference among groups regarding valuing social and emotional benefits and ease of use in deciding to use mobile technology during COVID-19.

Discussion and Implications: COVID-19 impacted mobile technology use in all ages, but age groups were found to use mobile technology for different purposes. Still, people of all ages increased their interest in the benefits of using mobile technology and decreased their focus on ease of use. COVID-19 coincidentally created a suitable environment to introduce mobile technology remote services widely to an aging population.
Dilated Cardiomyopathy – Exploring the Underlying Causes
Authors: Wieczorek David
Published: January 2025

Cardiovascular disease is one of the world’s leading causes of natural mortality, taking approximately 18 million lives each year. Dilated cardiomyopathy, a subgroup of cardiac diseases, has an annual incidence of 5 – 8 cases per 100,000 for European and North American populations. Common features of dilated cardiomyopathy include cardiac chamber enlargement, impaired systolic function, reduced ejection fraction, and arrhythmias, with an endpoint of ventricular dilation and heart failure. The focus of this paper is to review the non-genetic and genetic etiologies that lead to dilated cardiomyopathy. The non-genetic causes of dilated cardiomyopathy that are discussed include viruses, cardiotoxicity, recreational drugs, and chemotherapeutic medications. For the genes that lead to dilated cardiomyopathy, the focus of this paper is on cytoskeletal and sarcomeric protein genes. Our scope in defining this area will be to explore numerous mouse models that incorporate mutations found in humans that lead to dilated cardiomyopathy. The purpose of the paper is to define the morphological and physiological consequences of these mutations and how this information has furthered our understanding of the disease. Having gained invaluable knowledge from these animal models, it is hoped that new and improved therapeutic approaches can be developed for the treatment and prevention of dilated cardiomyopathy.
Framework for strategic foresight in dementia care in Portugal
Authors: Valverde Ana , Albuquerque Ana , Pavão José , Barros Raquel , Meira Bruna , Lopes Henrique
Published: January 2025

Introduction: Neurological disorders have become the leading cause of global disease burden, posing a significant public health challenge. With an aging global population, conditions like Alzheimer's disease and other dementias are expected to increase demands on healthcare services. Variations in risk factors and healthcare services across the country are impacting the diagnosis, treatment, care, and support, with many regions lacking sufficient resources. Additionally, there is a need to improve monitoring of dementia-related metrics and advance research, particularly regarding treatment and access to clinical trials. This study provides an overview of the current care landscape for dementia patients by analyzing real-world-based data. Gaps and challenges in dementia care, as well as suggestions for optimal care, are discussed.

Methods: Three plenary sessions were held, gathering healthcare professionals experienced in dementia care, along with representatives from patient associations. During these virtual meetings, participants shared their insights and discussed the current state of dementia care and treatment in Portugal. Key factors were proposed to guide a roadmap for transitioning from scenario planning to concrete strategic actions.

Results: National dementia care initiatives with implications for care quality were analyzed. The incidence of dementia continues to rise, including in Portugal, although comprehensive data remains limited. Dementia poses a significant healthcare challenge, necessitating a multidisciplinary approach at every stage of the disease.

Conclusion: Countries need detailed national plans that outline how resources will be allocated to enhance dementia awareness, train and support caregivers, and mobilize efforts to reduce risk factors and strengthen research capabilities. These plans should be shaped by input from consumers and adapted to local contexts, aiming to create an inclusive society for individuals living with dementia and their families.
Role of IL-18 in Asthma
Authors: Wang Junling , Zhan Mengmeng , Liu Shihao , Wang Siqin , He Shaoheng
Published: January 2025

Asthma is a common heterogeneous disorder characterized by chronic airway inflammation, remolding and hyperresponsiveness. Although substantial advance has been achieved in understanding its complex pathogenesis, which involves genetic factors, environmental exposures, and immune system imbalances, the effective clinical therapeutics of asthma remains challenging. IL-18, a pleiotropic cytokine of IL-1 superfamily produced mainly by monocyte-macrophage system, is an imperative participant in the pathology of asthma through interacting with IL-18R, and is likely to be the potential targets for the diagnosis and therapeutics of asthma. In this review, we addressed briefly the phenotypes and endotypes of asthma. Then we introduced the regulation mechanisms of the IL-18 production, and summarized the roles of IL-18 in the pathogenesis of different asthma endotypes, in particular emphasizing the roles of IL-18 alone and IL-18 in synergy with other cytokines. Furthermore, we highlighted the effects of IL-18 on airway pathological characteristics and disorder severity of asthma. Finally, we discussed the future research directions and challenges based on IL-18 therapy, which is expected to provide novel ideas for the precise treatment of asthma.
Due Diligence for Theft and Control of Tractions in Mines
Authors: Pandiyan V. , Rajeev P. R. , Seenivasan M. , Archana A.
Published: January 2025

These days’ security system for a vehicle is mandatory preferably in mines because to avoid unauthorized operation of traction vehicles and automobiles which is available because it is essential. When the burglar steals the vehicle, locating of the lost vehicle is not possible and identifying the thief is also not easy. So, in this article by introducing a security system which can locate and identify the thief by proposing face recognition technique for an auto safety system is used to recognize the true motivation face and compare it to a predefined face using face detection and identification technique. The suggested vehicle safety system performs real-time user authentication with computational assistance. Once the image from the activated camera becomes available, the person's face is recognized using the HAAR cascade method, and the extracted face is compared to the trained image. If someone's visage is recognized as an unknown individual this integrated. The system will send a picture of the individual to the driver via email utilizing the Internet Message Access connection and also, the mechanism remains lock by using electromechanical relay.
Electrochemical Synthesis of ZnO:CuO Nanocomposites for Photodegradation Studies of Cibacran Brilliant Yellow Dye and Textile Dyeing Industry Effluent
Authors: Chaitanya Lakshmi G.
Published: January 2025

Zno:Cuo nanoparticles are synthesised by electrochemical method and were characterised by UV-visible spectroscopy, infrared- spectroscopy, scanning electron microscopy, X-ray diffraction, positron annihilation lifetime spectroscopy and density measurements. The band gap energy of ZnO:CuO nanocomposite was 3.05 eV. The size was found to be 9.9nm by XRD studies. The nanocomposites consist of more defects and vacancies than ZnO. The photocatalytic efficiency of the sample was investigated systematically on Cibacran brilliant yellow 3G-P dye and a textile dyeing industrial effluent.
Development of Pulse/Direct Electrodeposition, Characterisation and Mineralised Antibacterial Activity of Platinum Coatings on SS304
Authors: Devendra Bharath K. , Praveen B. M. , Tripathi V. S. , Kumar H. P. Prashanth , Rajappa S. K. , Smrithi S. P.
Published: January 2025

The current investigation meticulously tracks the advancement, metallurgical delineation and deployment of Platinum 5Q solution onto the SS304 matrix, harnessing its mineralised prowess as a potent antibacterial agent. Pulsed Electrodeposition (PC) with platinum bath solution was used to develop coatings on a substrate with different duty cycle PC 25%, 50% and 75% and Direct Current (DC) source as a comparative study for the electrodeposition performance against the bacterial activities. Scanning Electron Microscope (SEM) and Atomic Force Microscope (AFM) were used to observe the newly developed platinum on the substrate. Utilising the broth culture and agar petri plate technique, the antibacterial activity of Pt using DC and PC methods was tested against Gram-negative E. coli and Gram-positive bacteria such as Staphylococcus saprophytieus, Bacillus stilis and Enterococcus faecalis. Platinum metal ions activity was compared to platinum solution and platinum-coated samples in terms of mineralised efficacy. The platinum coating obtained from PC 75% has significant antimicrobial activity against Enterococcus faecalis microorganisms experienced, according to the findings. As the concentration of platinum metal ions increased, so did the antibacterial activity. The study’s discoveries indicate that electrodeposited platinum metal ions hold promise as prospective mineralised antibacterial defenders in the times ahead.
Stability of antioxidative, peroxidative, and stress genes of food materials in different packaging materials at refrigerated condition
Authors: Mankal Nitya , Mandal Nabanita , Rajagopal Senthilkumar
Published: January 2025

Traditional food packaging materials include glass, metals, paper and paperboard, and plastics. The stability of antioxidants depends on storage temperature, storage time, and type of packaging material. After stress exposure, gene expression is tightly controlled and reversible. Various molecular pathways that are very dependent on the specific stress and organism type are used to do this. The current study intends to examine the stability of lipid peroxidative, stress genes, and antioxidants in fruits and vegetables stored in various packaging materials under refrigeration at specified time intervals. The stability of antioxidants, lipid peroxidative, and stress genes in various packaging materials, including plastic containers, brown paper covers, and zip lock covers, under refrigeration conditions (5 ℃–6 ℃) at control, 1st day, and 15th day, was investigated in this study using fruits and vegetable such as tomato and lemon. Parameters were estimated in various technical methods and expressions of genes were done by PCR and visualized by agarose gel electrophoresis. The stability of antioxidants, lipid peroxidative, and electrolytes status was significantly altered while keeping the food materials in various packaging materials at specified time intervals. In addition, the expressions of stress genes were significantly downregulated by storing the food material in various packaging materials, especially plastic containers at specified time intervals. In conclusion, no packaging materials are suitable for retaining antioxidants, lipid peroxidative, and stress genes of food materials under refrigerated conditions.
O discurso neoliberal no Ensino Médio: o Projeto de Vida e a construção do empreendedor de si
Authors: Rodrigues Adriege Matias , Rodrigues Ana Cláudia da Silva
Published: January 2025

Este artigo aborda o Projeto de Vida (PV), componente curricular que ganhou centralidade na Reforma do Ensino Médio. Com o objetivo de entender os efeitos do discurso neoliberal, do empreendedor de si, no componente curricular Projeto de Vida, neste artigo são analisadas as respectivas políticas de orientações curriculares – Lei nº 13.415/2017; BNCC (2018) e Diretrizes Operacionais da Paraíba (2024) – que apresentam os principais elementos para orientar as discussões em torno do PV nas escolas, além da entrevista realizada com jovens de João Pessoa – PB. Metodologicamente, operamos com a abordagem qualitativa e, para a análise dos achados, dialogamos a partir da Análise do Discurso com base em Foucault (1986). Evidenciamos que o componente curricular Projeto de Vida se caracteriza como um instrumento de poder do Estado que busca moldar e governar os/as estudantes, prescrevendo um perfil de sujeito para atender às demandas econômicas de uma política neoliberal que tem como alicerces a eficiência, o desempenho e a rentabilidade, além de promover a noção do indivíduo como empreendedor de si mesmo.
Um olhar sobre a BNCC: reflexões acerca do novo currículo do ensino médio no estado do Piauí
Authors: Guedes Neide Cavalcante , Ferreira Maria Núbia da Silva
Published: January 2025

Considerando que os debates em torno do Novo Ensino Médio se constituem em elementos para avaliar como esse processo vem ocorrendo nos estados, o artigo tem como objetivo compreender o processo de implementação da Base Nacional Comum Curricular e a implantação do Novo Currículo do Ensino Médio do estado do Piauí a partir da organização prevista no documento. Nesse sentido, este artigo se debruça sobre a arquitetura geral do currículo constante no documento denominado “currículo do Piauí novo ensino médio” no sentido de identificar as competências gerais para a formação nesta etapa da educação básica considerando a expectativa dessa clientela. Para tanto, utilizamos uma abordagem qualitativa, que contou com uma pesquisa bibliográfica-documental. Adotamos como método a análise documental e a pesquisa bibliográfica com revisão de literatura sobre a nova Proposta Curricular e políticas públicas educacionais piauienses.