bluuebunny/crossref_metadata_2025 huggingface dataset:
“Seja feita a sua imagem e semelhança”: Os filmes estadunidenses da aids (anos 80)
Authors: Araujo Anderson Cunha de , Silva Renato Izidoro da
Published: June 2023

Trata-se de uma pequena exposição do levantamento e da categorização dos filmes lançados pelo cinema Estadunidense no período inicial da pandemia da AIDS nos Estados Unidos nas décadas de 1980 e 1990. Realizamos uma pesquisa exploratória que resultou no mapeamento e no resgate de obras cuja distribuição e o potencial comercial foram negligenciados pelo interesse das distribuidoras; muitas dessas obras sequer tiveram lançamento em DVD no Brasil. O interesse na pandemia de AIDS e a eventual divulgação dessas obras em cinema e locadoras de VHS e DVD da época foi um fenômeno restrito ao período estudado, apesar da pandemia ter se mantido até dos dias atuais. O interesse atual do cinema estadunidense parece ser o de resgatar esses primeiros anos numa revisão crítica contemporânea. Como nossa análise dissertativa foca no período estabelecido entre as décadas já citadas, de imediato percebemos uma relevante sequência de mudanças no perfil sociológico dos protagonistas das tramas fílmicas. Ressaltou aos olhos também as transformações narrativas acerca das dificuldades de tratamento e da luta dos movimentos sociais organizados LGBTS neste artigo iremos apresentar brevemente alguns aspectos centrais dessa nossa percepção em duas obras cinematográficas emblemáticas do período.
Parceiros, trabalhadores, quilombolas: narrativas e trajetórias de acesso à terra nos Quilombos do Imbé/RJ
Authors: Ribeiro Yolanda Gaffrée
Published: June 2023

Este artigo é parte da etnografia sobre o processo de reconhecimento das comunidades quilombolas em uma área rural da cidade de Campos do Goytacazes, região norte do Estado do Rio de Janeiro. Proponho analisar, então, o modo como os moradores afirmam vínculos de pertencimento ao território e sustentam suas demandas de direitos, a partir de um vir a ser quilombola nas arenas públicas. Para isso, mobilizo as narrativas que assumem centralidade e sustentam demandas de direitos, relacionadas à trajetória histórica local. Essas narrativas são elaboradoras face às diferentes dinâmicas de controle e subordinação, lembradas e vividas ao longo de gerações, bem como falam das condições para a sua superação. O programa de reforma agrária, por exemplo, pode ser pensado como um momento de ruptura com os modos de vida e relações de trabalho anteriores, sendo qualificado pelos moradores como parte das “conquistas” e “vitórias” alcançadas, ainda que se possa falar das ambiguidades em torno das condições de acesso à terra e das possibilidades de produção e comercialização dos alimentos.
Prevalência de hipertensão arterial e diabetes mellitus no Estado de Goiás: há uniformidade entre as fontes de informação?
Authors: Isaac Isabela Ghetti Macedo , Sardinha Andréia de Souza Franco , Carvalho Magna Maria de , Rebouças Alessandra Chrystina Ramos , Oliveira Sandra Pires de , Tavares Selma Alves de Oliveira
Published: June 2023

INTRODUÇÃO: Conformidadeentre asfontes de dados sobre diabetes mellitus(DM) e hipertensão arterial (HA) é fundamental para medidas de vigilância.OBJETIVO:Avaliar se há uniformidade entre os dadosde prevalência deDM e HAno Estado de Goiása partir deduas diferentesfontesde acesso a esses dados.CASUÍSTICA EMÉTODOS: Comparaçãoentre os dados do Levantamento de Hipertensão e Diabetes do estado de Goiás 2021 (LHD) e do banco de dados da Estratégia e-SUS Atenção Básica (e-SUS AB) com relação ao número de indivíduos cadastrados na rede de atenção primária à saúde com os diagnósticos de DM e HA. RESULTADOS: Em Goiás, a diferença entreo número absoluto de indivíduos com diagnóstico de DM e HA pelo LHD e pelo e-SUS ABfoi de 46,56% e de 27%, respectivamente (p <0,001). A diferença entre os dados foi maior que 50% para o diagnóstico de DMem 104 municípios e para HA em94 municípios. DISCUSSÃO: As divergências encontradas podem estar relacionadasa fatores como aqualidade dos dados fornecidospela população, duplicidade de registros, problemas técnicosrelacionados à interneteao software e dificuldades na integração entre os sistemas de informação. Demonstra-sea necessidade de padronização de registros e uniformização dos dados para o fortalecimento de ações de vigilância. CONCLUSÃO:Há inconsistências entre os dados sobre o número de indivíduos cadastrados com os diagnósticosde DM e HA a partir do LHD e e-SUS AB em grande parte dos municípios do Estado de Goiás.
Germination patterns and seedling growth of congeneric native and invasive Mimosa species: implications for risk assessment
Authors: Kharel Nisha , Dangol Anuj , Shrestha Ashmita , Airi Hemanti , Devkota Anjana , Thapa Lal , Shrestha Bharat
Published: June 2023

Comparisons of plant traits between native and invasive congeners are
useful approaches for identifying characteristics that promote
invasiveness. We compared germination patterns and seedling growth of
locally sympatric populations of native Mimosa himalayana and two
varieties of invasive M. diplotricha (var. diplotricha and var. inermis)
growing in south-eastern Nepal. Seeds were germinated under 12h
photoperiod or complete dark, low (25/15°C day/night) and (30/20°C) high
temperatures, different water stress levels, and soil depths. Plant
height, biomass allocations, and relative growth rate (RGR) of seedlings
were measured. Invasive M. diplotricha had higher germination
percentage, rate, and shorter germination time than native species.
Germination of both congeners declined as water stress increased, but
the decline was more pronounced in native species. Seedling emergence
declined with increasing depth in all taxa. The seedlings of invasive
species were taller with higher leaf number and allocated greater
proportion of biomass to shoot, while the native congener allocated
greater biomass to root. The RGR was nearly twice as high in invasive
species as it was in native congener. Seedling height and number of
leaves were always higher in invasive than in native and the
native-invasive differences increased over time. Better germination and
higher growth performance of invasive species than congeneric native one
suggests that seed germination and seedling growth can be useful traits
for the prediction of species’ invasiveness in their introduced range
during risk assessment process.
PCBDet: An Efficient Deep Neural Network Object Detection Architecture for Automatic PCB Component Detection on the Edge
Authors: Li Brian , Palayew Steven , Li Francis , Abbasi Saad , Nair Saeejith , Wong Alexander
Published: June 2023

There can be numerous electronic components on a given PCB, making the
task of visual inspection to detect defects very time-consuming and
prone to error, especially at scale. There has thus been significant
interest in automatic PCB component detection, particularly leveraging
deep learning. However, deep neural networks typically require high
computational resources, possibly limiting their feasibility in
real-world use cases in manufacturing, which often involve high-volume
and high-throughput detection with constrained edge computing resource
availability. As a result of an exploration of efficient deep neural
network architectures for this use case, we introduce PCBDet, an
attention condenser network design that provides state-of-the-art
inference throughput while achieving superior PCB component detection
performance compared to other state-of-the-art efficient architecture
designs. Experimental results show that PCBDet can achieve up to 2×
inference speed-up on an ARM Cortex A72 processor when compared to an
EfficientNet-based design while achieving ∼2-4% higher mAP on the
FICS-PCB benchmark dataset.
A SWOT Analysis of Software Development Life Cycle Security Metrics
Authors: Khan Rafiq Ahmad , Khalid Ayesha , Raza Mushtaq , Afsar Palwasha , Rehman Hanif Ur
Published: June 2023

Cybersecurity is an ongoing and critical concern because of the constant
and persistent threats from malicious actors such as hackers and
crackers. The widespread use of software systems has revolutionized
modern society in various aspects, but it has also brought forth new
challenges in safeguarding sensitive and confidential information with
the evolution of information and communication technology (ICT).
Quantifying security measures can provide evidence to support
decision-making in software security, especially when it comes to
evaluating the security performance of software systems. This involves
understanding the main quality criteria of security metrics, which can
aid in building security metrology models based on practical
requirements. To further explore this topic, this study conducted a
systematic literature review of security metrics and measures in the
context of Secure Software Development (SSD). The study selected 61
research studies based on specific inclusion and exclusion criteria and
extracted data from the selected articles. The study identified 215
software security metrics, which were then categorized based on Software
Development Life Cycle (SDLC) phases. To evaluate the effectiveness of
the most commonly cited metrics in each phase, the study applied a SWOT
analysis to highlight their strengths, weaknesses, opportunities, and
threats. The findings of this study offer valuable guidance to diligent
and motivated researchers to investigate emerging research trends and
address existing gaps in Secure Software Development. Furthermore, this
investigation provides software professionals with a more comprehensive
understanding of security measurements, constraints, and open-ended
specific and general issues.
Molecular characterisation and in silico analysis of the gene encoding 14-3-3 tegumental protein of Schistosoma spindale
Authors: Syriac Modi , Lakshmanan Bindu , Narayanan Priya Manakkulamparambil , Radhakrishnan Uma
Published: June 2023

BackgroundSchistosoma spindale is a highly prevalent and
pathogenic snail borne trematode of ruminants in the Indian
subcontinent. The zoonotic significance of this parasite is associated
with cercarial dermatitis in man. Human schistosome infection is
infamous for its high morbidity and mortality rates and, animal
schistosomosis adversely affects the livestock sector in endemic areas.
Several protein candidates of schistosomes have been characterised to
exploit the diagnostic and vaccine potential for the control of
infection in man and animals, amongst which tegumental proteins have
been found quite promising. However, such proteins of Indian
schistsosome species have not been yet studied systematically.
Objectives In this study, molecular characterisation of 14-3-3
tegumental protein encoding gene of S. spindale and in
silico analysis of the predicted protein structure were done to assess
its immunogenicity. Methods Kerala isolates of adult S.
spindale worms were collected from mesentery samples, Total RNA was
isolated and cDNA was synthesised from it. The synthesised cDNA was used
as a template for the PCR amplification of the Ss14-3-3 gene and the
confirmed amplicons were then column purified and bidirectionally
sequenced using Sanger’s di-deoxynucleotide chain termination method.
The sequences obtained were merged and subjected to further analysis
using bioinformatic tools. Results A 759 bp amplicon of 14-3-3
tegumental protein encoding gene of S. spindale was translated
into a protein sequence having 252 amino acids. The Ss14-3-3 nucleotide
sequence showed the highest similarity of 94.99 per cent with S.
bovis 14-3-3 zeta isoform mRNA. However, Ss14-3-3 protein sequence had
the highest similarity with the 14-3-3 putative protein of S.
mansoni (99.21 per cent). With the help of bioinformatic tools, it was
concluded that the secondary and tertiary structures of this protein
were stable and three potential B cell epitopes exists within the
translated protein sequence. The protein was shown to possess structural
stability and immunogenicity which makes it a potential immunogenic
candidate against schistosomosis. Conclusions A 14-3-3 tegumental
protein encoding gene of S. spindale was characterized for the
first time. Sequence data was generated and in silico analysis
revealed structural stability and possible immunogenicity. The study
would serve as a platform to unravel the characteristics of tegumental
proteins of animal schistosomes to be used in diagnostics and vaccines.
However, further wet lab experiments including expression studies are
necessary to validate these findings.
Priming of human bone marrow-derived mesenchymal stromal cells with various down-stream effectors of the Transforming Growth Factor 1 pathway boosts their hematopoiesis-supportive ability.
Authors: Kale Vaijayanti
Published: June 2023

Mesenchymal stromal cells (MSCs) isolated from various tissues are
frequently used to expand hematopoietic stem/ progenitor cells
(HSCs/HSPCs) in vitro. They are also co-infused with the HSCs to improve
the HSC engraftment. However, the MSCs sourced from non-hematopoietic
tissues could be less efficient in their hematopoiesis-supportive
ability. Likewise, the hematopoiesis-supportive ability of the MSCs is
known to decline after continuous in vitro culture – an unavoidable
manipulation to get clinically relevant cell numbers. Hence, it may be
necessary to boost the hematopoietic-supportive ability of the long-time
cultured MSCs before their clinical applications in hematological
disorders. In my earlier work, I showed that priming of MSCs isolated
from human bone marrow (BMSC) with Transforming Growth Factor β1 (TGFβ1)
boosts their hematopoiesis-supportive ability via activation of AKT-eNOS
pathway. Accordingly, I also demonstrated that priming the BMSCs with
nitric oxide (NO) donors mimics the effect of TGFβ1. Here I show that
brief exposure of human BMSCs to pharmacological modulators of PKC and
intracellular calcium – two downstream participants in the TGFβ1-eNOS
signaling pathway – also boosts their hematopoiesis-supportive ability.
Such an approach comprising priming the BMSCs with pharmacological
compounds for a short duration and briefly exposing the HSCs to them can
be used in clinical settings to improve the efficacy of stem cell
transplantations. This concept would be helpful in other regenerative
medicine protocols after identifying suitable pharmacological modulators
giving desired effects on the target cells.
Evaluation of the Application of Soil and Water Conservation Practices: A Case Study in Changting County, southeast China
Authors: 李 怡凤 , Ma Lihui , wang jijun , lian po , Ma lingna , Wen xin , Yue Hui
Published: June 2023

Soil and water conservation practices, governance processes, and
governance effects can be regarded as elements that constitute a unique
coupling system. In order to understand the operation of this coupling
system, a structural equation model was used to determine the coupling
paths and intensities based on field research data collected from 193
local households in Changting County, China during 2021. The results
showed that the elements within the coupling system remained unchanged
and the coupling state was steady, with the same coupling path
directions in 2010 and 2020. However, the intensities of the coupling
paths varied with different path coefficients, where they followed the
order of: governance process (0.99) > governance effect
(0.57) > coupling state (–0.39) in 2010; and governance
process (0.94) > coupling state (0.92) >
governance effect (0.17) in 2020. We conclude that although the elements
were optimized to a certain extent during the evolution of the coupling
system, the lack of harmony among ecological resources and industries
detrimentally affected the dynamics of the coupling system. Thus, the
government should focus on the harmonious development of ecological
resources and the integration of industries to facilitate the
high-quality development of ecological civilization.
Stratified management of cervical intraepithelial neoplasia grade 2 in women over 25 years old based on conization findings:A retrospective study
Authors: Jin Ping , Wang Huanhua , Jin Ling , Lin Qing , Kong Yanqing , Liu Peiyi
Published: June 2023

Objective: Partial patients diagnosed with CIN2 on biopsy
include CIN3 .To compare the histopathological
results before and after conization of CIN2 for exploring stratified
management for CIN2 in women aged ≥25 years. Design: A
observational retrospective study. Setting: China.
Population: 307 women aged 19~40 years
diagnosed as CIN2 on biopsy with cervical squamocolumnar junction
visible. Methods: Compared immediate conization specimen
histopathology with the biopsy histopathology,and explored the risk
factors to predict CIN3 in cone histopathology.
Main outcome measures: Cone-histopathology-grading rate of
CIN2. Risk factors predicting cone histopathology upgrading.
Constructing an individualized algorithm for CIN2 stratified management
using risk factors. Results: the cone-histopathology-upgrading
rate of CIN2 was 22.5%(including one case of cervical microinvasive
squamous cell carcinoma).In univariable analysis: age, HPV16/18, HSIL
cytology were high-risk factors of cone histopathology upgrading(CIN3
)(P<0.05). In multivariable analysis:
HPV16/18(OR 2.399,[95%CI 1.326-4.338]) and HSIL cytology(OR
3.295,[95%CI 1.622-6.692]) were independently risk factors.
Conclusion: CIN2 patients aged ≥25 years were with a higher
proportion of CIN3 and stratified treatment should
be considered.Patients with HPV16/18 infection and HSIL cytology owned
the highest rate of CIN3 in the rest cervix,surgical
treatment should be taken. For those with HPV16/18 infecton and
ASCUS/LSIL cytology, or other high-risk HPV infection and HSIL cytology
were with a relatively higher proportion of CIN3 ,
treatment should be individualized. However, for patients with HPV16/18
infection and NILM cytology or other high-risk HPV infection and
ASCUS/LSIL cytology, the risk of CIN3 was relatively
low,conservative treatment should be taken.
UV-C light: the future of disinfection of flexible endoscopes without a working channel?
Authors: Halmans Yana , Wellenstein David , Romijn Michael , Cremers Suzan , Smit Jannie J. , Hopman Joost , Takes Robert , Broek Guido van den
Published: June 2023

Objective: To investigate Colony-Forming Unit (CFU) reduction
on contaminated flexible endoscopes without a working channel after UV-C
light disinfection compared to the current disinfection method with the
Endoscope Washer Disinfector. Design, setting: After
pharyngolaryngoscopy, a manual pre-cleaning with tap water was
performed. A culture was then collected by rolling the distal 8-10 cm of
the flexible endoscope over an Agar plate. The flexible endoscope was
disinfected using the D60 (60-second disinfection process with UV-C
light) or the Endoscope Washer Disinfector (golden standard reprocessing
process with water and chemicals). Another culture was then taken. After
incubation, a CFU count was performed. Results: Two hundred
flexible endoscopes without a working channel were divided equally
between the two disinfection groups. After clinical use and manual
pre-cleaning, 84 of the 100 (84.0%) (UV-C light group) and 79 of the
100 (79.0%) (EWD) flexible endoscopes were contaminated with at least 1
CFU. Flexible endoscopes that showed no contamination after use were
excluded from further analysis. After disinfection with UV-C light, 72
(85.7%) flexible endoscopes showed no contamination (i.e. 0 CFUs)
versus 66 (83.5%) flexible endoscopes after reprocessing with the
Endoscope Washer Disinfector. Conclusion: There is no
difference in CFUs reduction on contaminated flexible endoscopes without
a working channel between UV-C light disinfection and the current gold
standard, the Endoscope Washer Disinfector.
Natural history of uterine fibroids during perimenopause and menopause
Authors: Louie Michelle , Kosiorek Heidi E. , Alsibai Reem A. , Browne Cherie-Akilah , Rassier Sarah , Laughlin-Tommaso Shannon
Published: June 2023

Since fibroids are known to be hormonally receptive tumors, it is
biologically plausible that fibroids decrease in size after menopause.
Patients may opt for more conservative therapy or expectant management
if fibroid growth could be predicted[1](#ref-0001). Studies
assessing fibroid growth in premenopausal patients have shown that
individual tumors in a single uterus grow at different rates and can
grow consistently or in short bursts . These
variations and the unknown effect of natural menopause make patient
counseling difficult. Studies that include only symptomatic menopausal
patients or those undergoing treatment can result in selection bias
towards fibroids that are increasing in size . The
objective of our study was to estimate fibroid growth course before and
after menopause among women not specifically seeking fibroid treatment.
Our hypothesis was that fibroid growth would decline after menopause.
Do Women Receive Worse Financial Advice? An Audit Study in Hong Kong, China
Authors: Bhattacharya Utpal , Kumar Amit , Visaria Sujata , Zhao Jing
Published: June 2023

This audit study examines whether financial advisors’ recommendations vary by client gender. It provides evidence that women are more likely than men to receive low-quality financial advice from some types of advisory firms. We explain this as the result of firms’ incentives and advisors’ beliefs about gender differences in financial knowledge.
Correlation analysis based on neural network copula function
Authors: Li Haibin , Sun Lijun , Yao Qinghu
Published: June 2023

The joint-distribution function between variables plays an important role in
reliability analysis. A method is proposed for constructing the function
using a neural network, which is used to construct a copula model under
arbitrarily measured data, including the input and output values of the
neural network using an empirical cumulative distribution. Three traditional
copula function models are constructed based on the Kendall rank-correlation
coefficients. Based on the Euclidean distance method, the neural network
copula and three copula function models are compared.
Bayesian inference for a simple step-stress accelerated dependent competing failure model
Authors: Wang Ying , Yan Zai-Zai
Published: June 2023

The Copula approach can be used to describe the dependence structure between
variables. In this paper, by using a Bivariate Clayton copula, we discuss
the statistical analysis of a simple step-stress accelerated dependent
competing failure model under progressively Type-II censoring sample. With
the assumption of cumulative exposure, the Bayesian estimations of the
model parameters are derived. Based on Monte-Carlo simulation, the
precision of the estimates is assessed. Finally, the statistical analysis
of an actual data set of a solar lighting insulation system has been
presented for illustrative purposes.
An on-line detection method for conveyor belt deviation faults
Authors: Liu Mingsheng , Mei Xiuzhuang , Sun Dongming , Zhang Jian , Chen Zelin
Published: June 2023

The conveyor belt deviation occurs frequently, and it will finally lead to an
accident, so its detection has triggered skyrocketing attention from both
industry and academia. In this paper, an adaptive segmentation model and a
belt offset quantification model are established for continuous online
detection of the conveyor belt deviation status. The results show that the
degree of the conveyor belt deviation can be quantitatively calculated and
its deviation status can be objectively evaluated. This technology has
opened the path for a new way to on-line continuously detect the conveyor
belt deviation.
Estimation of reliability in multicomponent stress-strength based on exponential Frechet distributions
Authors: Shang Li-Feng , Yan Zai-Zai
Published: June 2023

When strength and stress variables follow the exponential Frechet
distribution with different shape parameters and common scale parameters,
the multicomponent stress-strength reliability model of an s-out-of-k
system is studied in this paper. Based on samples from stress and strength
distributions, the maximum likelihood estimation of the model parameters is
obtained. The asymptotic confidence interval for the system reliability is
also calculated. The comparison of the reliability estimates based on small
sample is given by Monte-Carlo simulation.
Numerical analysis of space-time fractional Benjamin-Bona-Mahony equation
Authors: Lu Jun-Feng , Ma Li
Published: June 2023

This paper proposes a numerical approach based on the fractional complex
transform and the homotopy perturbation method to solving the space-time
fractional Benjamin-Bona-Mahony (mBBM) equation with Caputo fractional
derivative. Approximated solutions with high accuracy are provided without
linearization or complicated computation. Numerical examples are given to
illustrate the efficiency of this method.
Some notes on the maximum principle of semi-linear dynamical system
Authors: Deng Shuxian , Qi Lei , Li Ming
Published: June 2023

The maximum value principle plays an important role in the study of a
semi-linear system within a time domain, and it uses in this paper to study
the existence of solutions for systems with general non-linear terms.
Effect of louver angle on performance of parallel flow heat exchanger
Authors: Yang Fengye , Zhao Pengfei , Li Haijun , Kou Jingkang , Zhai Junjie , Wu Xiuqing
Published: June 2023

In order to study the influence of the louver angle on the heat transfer and
flow resistance characteristics of a parallel flow heat exchanger, this
paper establishes five calculation models including a uniform angle model
and four variable angle models for comparing and analyzing the temperature,
velocity, and pressure fields, and evaluates their comprehensive
performance. The results show that the suitable choice of the v louver angle
can lead to an optimal heat transfer effect and a best comprehensive
performance.
Energy performance assessment of virtually non-flammable mixtures for R134A applications
Authors: Qiu Fuqiang , Xu Taoping , Li Baoguo
Published: June 2023

In this study, three new mixed refrigerants with low GWP values,
R1234yf/R134a, R1234yf/R125, and R1234yf/R13I1, were evaluated as
replacements for R134a refrigerant using two vapor compression
configurations. The experiment revealed that these mixtures can be used as
environmentally friendly alternatives for this configuration.
Internal Control and the Insider versus Outsider CEO Choice
Authors: Baer Leah M. , Khurana Inder K. , Kyung Hoyoun
Published: June 2023

We examine whether the quality of a firm’s internal controls affects a board’s decision to hire an insider as CEO. We find that the board is less likely to select an insider as CEO following an internal control material weakness (ICMW) disclosure. In cross-sectional analyses, we find that the adverse effect of weak internal controls on the likelihood of hiring an insider CEO is attenuated for firms that restate past misstatements and is pronounced when boards are more independent. We also find that audit fees are lower for ICMW firms when an outsider CEO is appointed, indicating that external auditors perceive lower audit risk. Taken together, our findings suggest that in the presence of a weak internal control environment, the board prefers an outsider CEO over an insider who may have been a part of the internal control issues, notwithstanding the fact that evaluating the outsider CEO can be challenging.
Association of COVID-19 and Development of Type 1 Diabetes: A Danish Nationwide Register Study
Authors: Zareini Bochra , Sørensen Kathrine Kold , Eiken Pia A. , Fischer Thea K. , Kristensen Peter Lommer , Lendorf Maria Elisabeth , Pedersen-Bjergaard Ulrik , Torp-Pedersen Christian , Nolsoe Rúna L.M.
Published: June 2023

OBJECTIVE

To compare the incidence of type 1 diabetes (T1D) before and during the coronavirus disease 2019 (COVID-19) pandemic and determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with T1D development.

RESEARCH DESIGN AND METHODS

All Danish residents aged <30 years free of diabetes from 2015 to 2021 were included. Individuals were followed from 1 January 2015 or birth until the development of T1D, the age of 30, the end of the study (31 December 2021), emigration, development of type 2 diabetes, onset of any cancer, initiation of immunomodulating therapy, or development of any autoimmune disease. We compared the incidence rate ratio (IRR) of T1D using Poisson regression models. We matched each person with a SARS-CoV-2 infection with three control individuals and used a cause-specific Cox regression model to estimate the hazard ratio (HR).

RESULTS

Among 2,381,348 individuals, 3,579 cases of T1D occurred. The adjusted IRRs for T1D in each quarter of 2020 and 2021 compared with 2015–2019 were as follows: January–March 2020, 1.03 (95% CI 0.86; 1.23); January–March 2021, 1.01 (0.84; 1.22), April–June 2020, 0.98 (0.80; 1.20); April–June 2021, 1.34 (1.12; 1.61); July–September 2020, 1.13 (0.94; 1.35); July–September 2021, 1.21 (1.01; 1.45); October–December 2020, 1.09 (0.91; 1.31); and October–December 2021, 1.18 (0.99; 1.41). We identified 338,670 individuals with a positive SARS-CoV-2 test result and matched them with 1,004,688 control individuals. A SARS-2-CoV infection was not significantly associated with the risk of T1D development (HR 0.90 [95% CI 0.60; 1.35]).

CONCLUSIONS

There was an increase in T1D incidence during April–June 2021 compared with April–June 2015–2019, but this could not be attributed to SARS-CoV-2 infection.
Media Video Blogging pada Microlearning Materi Mitigasi Bencana
Authors: Susantyo Muhammad Ilham Athalla Naufal , Sahrina Alfi , Soekamto Hadi , Bachri Syamsul
Published: June 2023

Penelitian ini didasari atas materi mitigasi bencana yang perlu pemahaman nyata, namun ditemukan kendala berupa keterbatasan ruang dan waktu. Penelitian ini bertujuan untuk menciptakan media vlog (video blogging) pada microlearning materi mitigasi bencana. Penelitian dilakukan dengan inovasi teknologi dan microlearning berupa vlog. Media seharusnya disesuaikan dengan kebutuhan dan karakter siswa. Pengembangan dilakukan dengan model ADDIE. Subjek penelitian terdiri dari siswa-siswi pada kelas XI IPS 4 dan satu guru Geografi. Metode pengumpulan data dengan angket. Analisis data dilakukan pada hasil validasi berupa kritik serta saran dengan angket terbuka dan data tanggapan oleh guru dan siswa dengan angket semi terbuka sebagai bentuk data kualitatif dan kuantitatif. Validasi memperoleh rekomendasi “sangat layak” oleh ahli media dan “layak dengan revisi kecil” oleh ahli materi dan dilakukan revisi. Tanggapan pada tahap implementasi diperoleh skor rata-rata 89% oleh siswa dan 95% oleh guru yang keduanya termasuk dalam kualifikasi “sangat baik” atau sesuai dengan kebutuhan, yang mana media dapat menjadi alat bantu pembelajaran dan acuan penelitian lanjutan terkait kekurangan. Implikasi penelitian ini diharapkan dapat memberikan tools tambahan sebagai wadah untuk peserta didik jika ingin mempelajari materi yang lebih dalam.
Relações entre Tecnologias e História nos Anais do Seminário Nacional de História da Matemática
Authors: Castillo Bracho Luis Andres , Sánchez Ivonne Coromoto Sánchez , Mendes Iran Abreu
Published: June 2023

Este artigo é resultado de um estudo que teve como fontes de pesquisa os trabalhos publicados nos Anais do Seminário Nacional de História da Matemática entre 1995–2021. Fazendo um recorte deste estudo, foram selecionados trabalhos que tivessem possibilidades de conexões entre Tecnologias Digitais e a História da Matemática para o ensino analisados para compor o corpus deste texto. Estabelecemos como objetivo analisar quais abordagens metodológicas-didáticas. Para isto, foi necessário realizar um levantamento e revisão de literatura das produções a fim de operacionalizar uma análise preliminar nesses trabalhos. Os resultados apontam a tecnologia digital com predomínio dos softwares de Geometria Dinâmica, em particular Cabri II e GeoGebra, utilizados na maioria das produções para representação e exploração gráfica de problema e teoremas de tratados matemáticos antigos.
Philosophical Horizonts of Virtual Reality. Review of: Chalmers, D. (2022). Reality +: Virtual Words and the Problems of Philosophy. New York: W. W. Norton & Company. pp. 503
Authors: Holomsha Oksana , Minkovets Liudmyla
Published: June 2023

The review is devoted to the new monograph "Reality +: virtual worlds and problems of philosophy" by the famous philosopher David Chalmers. As can be seen from the title of the book, in it the author examines the philosophical potential of virtual reality for the possible solution of philosophical problems, namely: from ontology (problems of reality and hypotheses about simulation) to values (a good and happy life in virtual reality).
Wilderness as Challenge for Moral and Valuable Representations of a Human Being. Review of: Duclos, J. S. (2022). Wilderness, Morality, and Value. Lanham: Lexington Books. pp.141.
Authors: Karivets Ihor
Published: June 2023

A reviewed monograph considers the problem of wilderness. According to the author, wilderness should be considered as wilderness. Wilderness as wilderness overcomes the anthropocentric and non-anthropocentric limitations of all attempts to theoretically justify the need to protect wilderness, including environmental philosophy, bioethics, religious concepts of the environment, etc. Therefore, the author of the monograph offers a "nobody's and nowhere" view of wilderness and only it can reveal the true value of wilderness as such.
The effect of biochemical oxidation on the hydrometallurgical production of copper
Authors: Koizhanova Aigul , Magomedov David , Abdyldayev Nurgali , Yerdenova Maria , Bakrayeva Akbota
Published: June 2023

The article presents the results of the use of the biochemical leaching method for copper-bearing non-commercial ore in a full hydrometallurgical cycle. The object of the study was the average copper-bearing ore of the Satbayev deposit, with an initial copper content of 0.26%. The experimental part of the full hydrometallurgical cycle included percolation leaching, extraction, and re-extraction tests, as well as electrodeposition tests and the production of finished cathode copper. Two variants of percolation leaching were performed as a comparison: a standard method using only sulfuric acid and a preliminary bacterial oxidation method for mineral raw materials with an adapted bacterial strain, Acidithiobacillus ferrooxidans. Percolation leaching experiments showed a significant reduction in sulfuric acid consumption when preliminary bacterial oxidation was used. Upon reaching the level of copper extraction from the ore of 86–87%, the final consumption of sulfuric acid for the standard leaching method was 15.5 kg per ton, while 9.4 kg per ton was required for the biochemical method. The productive solution obtained in the biochemical leaching process showed full suitability for all technological stages of hydrometallurgical copper production.
Lifestyle-associated risk factors affecting young people
Authors: Aminova OS
Published: June 2023

The lack of a well-defined healthy lifestyle culture adopted by young people is one of the reasons behind them developing chronic non-communicable diseases. The review summarizes the results of a number of scientific investigations of the relationship between behavioral risk factors and health indicators as registered in the working and studying youth; we present the values reflecting the relative link between onset of chronic diseases and alcohol consumption, smoking, low physical activity, sleep disturbance, nutritional habits and use of gadgets, and highlight the specific aspects of how the risk factors associated with the lifestyle of youth are perceived.
The Relationship Between Intrapersonal Intelligence and Learning Independence of Students
Authors: Jannah Misbakhul
Published: June 2023

This study aims to determine the level of intrapersonal intelligence, independence of learning, and the relationship between intrapersonal intelligence and learning independence of students. The approach in this study uses a quantitative approach with descriptive and correlational research types. The object of the research is 144 students of class XI, determined by the Slovin formula from a population of 223 students. The instrument used is intrapersonal intelligence scale and independence of learning scale. This study uses descriptive statistical analysis techniques and correlational analysis. The results showed that the dominant student's intrapersonal intelligence was in the high category with a percentage of 72%, and the student's learning independence was relatively in the medium category with a percentage of 56.25%. While the relationship between intrapersonal intelligence and learning independence of students shows a correlation value of 0.062, meaning that there is no relationship between intrapersonal intelligence and independence of learning.
Critical Review of Substantive Due Process of Law: Discussion on the Necessity of Substantive Due Process of Law in the Korean Constitution
Authors:   Korean Association of International Association of Constitutional Law, Kim Jong-Hyun
Published: June 2023

The origin of the due process of law goes back to the Constitution, and it was stipulated in the Amendments to the United States Constitution and established as a principle governing the procedural and substantive aspects of governmental actions that deprive life, liberty, and property. The substantive due process was accepted as a criterion for judicial review after the 1880s, and became the basis for invalidating various economic regulatory legislation in the Lochner era. Since the 1960s, the U.S. Supreme Court has derived several fundamental rights not enumerated in the Constitution based on the substantive due process doctrine. The due process of law was first introduced into Korean legal order during the period of the U.S. Military Government in Korea. Article 12 of the current Constitution stipulates due procedures. The Constitutional Court and mainstream theories acknowledge that the provision is an adaptation of the Anglo-American due process of law. However, opinions differ as to whether the substantive due process is necessary in the Korean Constitution. In the United States, the substantive due process is criticized as a conceptual contradiction and that the courts take the place of other institutions. Some argue that the due process of law was procedural in its history, and that fundamental rights should be derived from other constitutional provisions. It is also pointed out that there is inconsistency in the specific application of the due process principle, and that there are limitations in determining fundamental rights based on historical and traditional standards. The practical significance of the substantive due process principle cannot be overlooked. However, in order for the substantive due process principle to be recognized in the Korean Constitution, it needs to be supported by convincing arguments. Korea is a single country, has a general provision on the limit of restriction of constitutional rights, and has a detailed list of fundamental rights, leaving less room for the substantive due process to operate than the United States. However, the arguments presented from the standpoint of affirming the necessity of the substantive due process of law are insufficient. In addition, it is judged that the substantive due process of law has not established itself as an independent judicial review standard in the Korean Constitutional Court, at least until now.
The Prohibition of Constitutional Complaint against a Trial and the Scope of the decision to cancel by the Constitutional Court
Authors:   Korean Association of International Association of Constitutional Law, Son Sangsik
Published: June 2023

Even if the Constitutional Complaint for a trial is exceptionally possible, it is necessary to distinguish whether the subject of the Constitutional Complaint is a “judgment subject to retrial” or a “judgment to dismiss a retrial.” According to the Constitutional Court, even if it cancels the “judgment to dismiss the retrial,” it cannot cancel the “judgment subject to retrial.” However, as long as the court's judgment is contrary to the effect of the Constitutional Court's unconstitutional decision, the scope of a trial subject to a Constitutional Complaint cannot be changed by the accidental factor of whether the Constitutional Court's unconstitutional decision is sentenced before or after the “court's judgment.” In order to control the case that provided the cause of the retrial request, at least the retroactive effect of the unconstitutional decision should be recognized in the case where a limited unconstitutional decision is sentenced after a trial applying the law before the Constitutional Court decides it is unconstitutional. This is because the scope of recognition of the trial court is in line with the scope of the retroactive effect of the unconstitutional decision. Therefore, at least the final judgment that provided the cause of the request for retrial, the court's judgment to dismiss the request for retrial, and the Constitutional Court's decision to cancel all of them are on the same line, so it would be reasonable to cancel not only the “judgment of dismissal of retrial” but also the “judgment subject to retrial” through the Constitutional Complaint against a trial, and to sentence the decision to confirm unconstitutionality for the legal provisions on the basis of the “judgment subject to retrial.”
Correlation of lactulose-to-mannitol ratios in plasma and urine for intestinal permeability assessment in pigs
Authors: Hu Steven X. , Benner Charles P. , Fuller Troy E.
Published: June 2023

OBJECTIVE

The lactulose-to-mannitol ratio test is a test to assess the disorders associated with gut permeability. The test requires an oral administration of the mixture of lactulose and mannitol and urine collection. The urinary ratio of lactulose to mannitol is an indicator of intestinal permeability. Due to the complexity of urine collection in animal studies, plasma exposure ratios of lactulose to mannitol compared to their urinary concentration ratios were evaluated following an oral administration of the sugar mixture in pigs.

ANIMALS

10 pigs were orally dosed with a solution of lactulose and mannitol mixture.

PROCEDURES

Plasma samples were collected at predose, 10 and 30 minutes and 2, 4, and 6 hours postdosing, and cumulated urinary samples were collected at 6 hours for liquid chromatography–mass spectrometry analysis. The ratios of pharmacokinetic parameters of lactulose to mannitol and the plasma sugar ratios at a single time point or the mean values of several time points were compared to their urinary sugar ratios.

RESULTS

The results revealed that the lactulose-to-mannitol ratios of AUC0–6h, AUCextrap, and Cmax were correlated to the urinary sugar ratios, and the plasma sugar ratios of a single time point at 2, 4, or 6 hours and the mean values of those time points were also appropriate to replace their urinary ratios in pigs.

CLINICAL RELEVANCE

Following an oral administration of lactulose and mannitol mixture, blood collection, and assay can be an option for assessing intestinal permeability, especially in animal studies.
STUDY ETNOGRAFI PEMBAYARAN OMPANGAN HAJATAN PERNIKAHAN DI DESA BATUKERBUY PAMEKASAN
Authors: Hotimah Hosnol , Baihaki Ach. , Zakhra Aminatus
Published: June 2023

Penelitian ini bertujuan untuk menganalisa pola transaksi keuangan atas pembayaran ompangan hajatan pernikahan di desa Batu Kerbuy Pamekasan dalam perspektif study etnografi, dengan jenis penelitian kualitatif deskriftif model Spradley. Hasil penelitian ini menunjukkan bahwa pembayaran ompangan atas sumbangan yang pernah diberikan sebelumnya, akan sangat bergantung kepada dua jenis alat pembayarannya, bisa terdiri dari uang ataupun barang. Nominal ataupun kuantitas yang harus dikembalikan akan sama-sama disadari oleh kreditur ataupun debitur berdasarkan instrumen budaya pendukung yang menyertai pelaksanaan remoh tersebut. Selain itu bisa bergantung pula kepada perakadannya, para pihak yang diundang, dan jenis undangan yang disebarkan. Pola pencatatannya juga menjadi unik, karena menggunakan organisasi sederhana kelompok remoh yang juga menyiapkan juru tulis sebagai bagian dari proses pencatatannya.
SISTEM INFORMASI AKUNTANSI ATAS PENGENDALIAN PERSEDIAAN PADA REJEKI 2 SWALAYAN DI OMBEN SAMPANG
Authors: Mafrudah Ana , Sakdiyah Halimatus
Published: June 2023

Penelitian ini bertujuan untuk mengetahui sistem informasi akuntansi atas pengendalian persediaan pada Rejeki 2 Swalayan di Omben Sampang. Jenis penelitian yang digunakan kualitatif deskriptif dimana tujuannya adalah menggambarkan secara sistematis tentang sistem informasi akuntansi atas pengendalian persediaan barang dagang. Data dikumpulkan dengan cara observasi,interview,dokumentasi. Hasil penelitian menunjukkan bahwa sistem informasi akuntansi atas pengendalian persediaan yang dimiliki oleh Rejeki 2 swalayan di Omben Sampang sudah baik. Namun masih ada kekurangan juga di dalam sistemnya yaitu tidak menggunakan buku besar dan buku pembantu. menggunakan buku besar dan buku pembantu untuk mempermudah transaksi.
Gemeinschaft im Wandel: Die deutsche Minderheit in Dänemark
Authors: Thaler Peter
Published: June 2023

Dieser Aufsatz zeichnet die Geschichte der deutschen Nordschleswiger von der Herausbildung einer eigenen Identität zu Beginn des 19. Jahrhunderts über die langanhaltenden Wirren des nationalen Konflikts bis hin zu den Herausforderungen einer zunehmend globalisierten und individualisierten Gesellschaft heute nach. In dieser Zeit waren sie Bürger in der dänischen Doppelmonarchie, in Preußen und im Deutschen Reich sowie in dem kleinen dänischen Nationalstaat, der sich nach 1864 entwickelt hatte. Ihr Selbstverständnis war immer wieder Prüfungen und Anpassungen unterworfen. Doch auch zu Beginn des einundzwanzigsten Jahrhunderts sind die deutschen Nordschleswiger ein fester Bestandteil der dänischen Gesellschaft.
Yavru gökkuşağı alabalıkların beslenmesinde fındık küspesi ve zeolit kullanımının büyüme performansı, sindirim oranı ve besin kalitesi üzerine etkilerinin araştırılması
Authors: ÖZPOLAT Emine , TUNA KELEŞTEMUR Gülüzar , ÖRNEKÇİ Gürel , USLU Ali Atilla , KARAKAYA Gökhan , DEMİR Timur , CELAYİR Yasin , DANABAŞ Durali , USLU ŞENEL Gülşad
Published: June 2023

Bu araştırmada yavru alabalık yemlerinde protein kaynağı olarak farklı oranlarda fındık küspesi ve zeolitin kullanımının balıkların büyüme performansları, yem değerlendirme ve sindirilebilme oranları üzerine olan etkileri araştırılmıştır. Bu amaçla; 9 farklı diyet ile 90 gün boyunca beslenen yavru alabalıkların (ortalama 13,35 gr) canlı ağırlık artışları belirlenmiştir. Sonuçlara göre, fındık küspesinin % 25 ve zeolitin % 6 oranında kullanıldığı rasyon ile beslenen yavru balıkların kontrol grubuna göre daha iyi büyüme gösterdikleri belirlenmiştir Yavru Gökkuşağı alabalıklarının diyetlerinde balık unu yerine fındık küspesi ve zeolit kullanımının büyüme, yem değerlendirme ve sindirilebilme oranları üzerine olumsuz bir etkisinin olmadığı ve bu oranlarda kullanılabileceği tespit edilmiştir.