bluuebunny/crossref_metadata_2025 huggingface dataset:
Variable Strength in Thoron Interference for a Diffusion-Type Radon Monitor Depending on Ventilation of the Outer Air
Authors: Omori Yasutaka , Shimo Michikuni , Janik Miroslaw , Ishikawa Tetsuo , Yonehara Hidenori
Published: February 2020

Thoron interference in radon measurements using passive diffusion radon detectors/monitors is a crucial problem when it comes to assessing the internal exposure to radon precisely. The present study reported, as one of the potential factors, the effects of air flow conditions on changes in thoron interference. Rates of thoron infiltration (as thoron interference) into the diffusion chamber of the monitor were evaluated. The temporal variation was obtained based on measurements of the underfloor space of a Japanese wooden dwelling using a diffusion-type radon monitor, a reference radon monitor which was not affected by thoron interference, and a thoron monitor. The thoron infiltration rate for the diffusion-type monitor varied from 0% to 20%. In particular, it appeared to increase when ventilation of the underfloor space air was forced. The variable thoron infiltration rate, with respect to ventilation strength, implied that not only a diffusive process, but also an advective process, played a major role in air exchange between the diffusion chamber of the monitor and the outer air. When an exposure room is characterized by the frequent variation in air ventilation, a variable thoron response is considered to occur in radon–thoron discriminative detectors, in which only diffusive entry is employed as a mechanism for the discrimination of radon and thoron.
Evaluation of the Pre-Planned and Non-Planed Agility Performance: Comparison between Individual and Team Sports
Authors: Mackala Krzysztof , Vodičar Janez , Žvan Milan , Križaj Jožef , Stodolka Jacek , Rauter Samo , Šimenko Jožef , Čoh Milan
Published: February 2020

This study assessed differences in agility performance between athletes of team and individual sports by assessing change-of-direction speed (CODS) as pre-planned agility and reactive agility (RA) as non-planed in different spatial configurations. The study involved 36 individual (sprint, hurdles, jumping, tennis, and judo) and 34 team (soccer, basketball, and handball) athletes. CODS and RA were measured with a light-based reactive training system in a frontal (FR), universal (UN), semicircular (SC), and lateral (LA) design. Lower limb power and sprint performance were also measured in a 10 m single leg jump test and 15 m sprint. Individual athletes showed significantly better performance in three of the eight agility tests: LA-RA, UN-RA, and SC-CODS (p < 0.008, p < 0.036, and p < 0.027, respectively) and were found to present stronger correlations (p < 0.01) between jump test performance and the CODS condition. Team athletes showed stronger associations between sprint performance and the CODS condition. In the RA condition both jump and sprint performance showed stronger correlations in the group of individual athletes. Agility performance as measured by CODS and RA should improve with enhanced of motor proficiency. Finally, the tests applied in this experiment seem to be multidimensional, but require spatio-temporal adjustment for their implementation, so that they meet the requirements of the particular sport.
Ethical Leadership as the Reliever of Frontline Service Employees’ Emotional Exhaustion: A Moderated Mediation Model
Authors: Zhou Hao , Sheng Xinyi , He Yulin , Qian Xiaoye
Published: February 2020

Based on the conservation of resources theory, this study aims to create new knowledge on the antecedents of emotional exhaustion. We explore the internal mechanism and boundary conditions of the impact of ethical leadership on emotional exhaustion, using data gathered from 460 frontline service employees at an airport in China. Employees completed questionnaires regarding ethical leadership, emotional exhaustion, organizational embeddedness, job satisfaction, and demographic variables. After controlling for the effects of demographic variables and company tenure, ethical leadership was found to have a negative impact on emotional exhaustion (β = −0.128, p < 0.01), and to be positively related to organizational embeddedness (β = 0.518, p < 0.01). After adding in the mediating variable (organizational embeddedness), the effect of ethical leadership on emotional exhaustion was no longer significant (β = 0.012, ns), while organizational embeddedness emerged as significantly related to emotional exhaustion (β = −0.269, p < 0.01), implying that the effect of ethical leadership on emotional exhaustion was completely mediated by organizational embeddedness. Simultaneously, the results suggested that job satisfaction could strengthen the mediating effect of organizational embeddedness on emotional exhaustion (the difference in the mediating effect between the groups with respective high and low job satisfaction was −0.096, p < 0.05). This study proposed and validated a moderated mediation model, the implications of which are that ethical leadership is an effective way to alleviate frontline service employees’ emotional exhaustion.
Use of Electronic Cigarettes in Smoke-Free Spaces by Smokers: Results from the 2014–2015 Population Assessment on Tobacco and Health Study
Authors: Dunbar Zachary R. , Giovino Gary , Wei Binnian , O’Connor Richard J. , Goniewicz Maciej L. , Travers Mark J.
Published: February 2020

Background: Smoke-free air policies exist to protect users and nonusers from exposure to tobacco smoke. Although electronic nicotine delivery systems (ENDS) may expose passerby to nicotine and particulate matter, few US states regulate indoor use of ENDS. The purpose of this study was to investigate reported rationales for ENDS use and reported ENDS use in public smoke-free places by dual cigarette/ENDS users. Methods: A population of ENDS/cigarette co-users (n = 2051) was drawn from Wave 2 of the Population Assessment of Tobacco and Health (PATH) dataset (2014–2015). Harm reduction beliefs and cessation behavior of co-users were investigated as predictors of ENDS use in public smoke-free places using logistic regression. Results: Fifty-eight percent of dual users reported past 30-day ENDS use in public smoke-free places. Reported use of ENDS to cut down on cigarette smoking (OR: 2.38, 95% CI: 1.86, 3.05), as an alternative to quitting tobacco (OR: 1.71, 95% CI: 1.37, 2.13), or because of belief that ENDS help people to quit cigarettes (OR: 1.52, 95% CI: 1.20, 1.92) were significantly associated with increased odds of ENDS use in smoke-free places. Conclusions: Beliefs that ENDS were useful as cessation tools or posed modified risk to users and nonusers were associated with elevated odds of use ENDS in locations where conventional tobacco is prohibited. Due to limitations in the survey instrument, in-home ENDS use could not be directly assessed in this analysis. However, these self-reported findings suggest that use of ENDS in public places where cigarette use is prohibited is prevalent enough to be of concern for future regulation and enforcement efforts.
Towards Detecting Building Facades with Graffiti Artwork Based on Street View Images
Authors: Novack Tessio , Vorbeck Leonard , Lorei Heinrich , Zipf Alexander
Published: February 2020

As a recognized type of art, graffiti is a cultural asset and an important aspect of a city’s aesthetics. As such, graffiti is associated with social and commercial vibrancy and is known to attract tourists. However, positional uncertainty and incompleteness are current issues of open geo-datasets containing graffiti data. In this paper, we present an approach towards detecting building facades with graffiti artwork based on the automatic interpretation of images from Google Street View (GSV). It starts with the identification of geo-tagged photos of graffiti artwork posted on the photo sharing media Flickr. GSV images are then extracted from the surroundings of these photos and interpreted by a customized, i.e., transfer learned, convolutional neural network. The compass heading of the GSV images classified as containing graffiti artwork and the possible positions of their acquisition are considered for scoring building facades according to their potential of containing the artwork observable in the GSV images. More than 36,000 GSV images and 5000 facades from buildings represented in OpenStreetMap were processed and evaluated. Precision and recall rates were computed for different facade score thresholds. False-positive errors are caused mostly by advertisements and scribblings on the building facades as well as by movable objects containing graffiti artwork and obstructing the facades. However, considering higher scores as threshold for detecting facades containing graffiti leads to the perfect precision rate. Our approach can be applied for identifying previously unmapped graffiti artwork and for assisting map contributors interested in the topic. Furthermore, researchers interested on the spatial correlations between graffiti artwork and socio-economic factors can profit from our open-access code and results.
IL-20 in Acute Kidney Injury: Role in Pathogenesis and Potential as a Therapeutic Target
Authors: Lin Tian-Yu , Hsu Yu-Hsiang
Published: February 2020

Acute kidney injury (AKI) causes over 1 million deaths worldwide every year. AKI is now recognized as a major risk factor in the development and progression of chronic kidney disease (CKD). Diabetes is the main cause of CKD as well. Renal fibrosis and inflammation are hallmarks in kidney diseases. Various cytokines contribute to the progression of renal diseases; thus, many drugs that specifically block cytokine function are designed for disease amelioration. Numerous studies showed IL-20 functions as a pro-inflammatory mediator to regulate cytokine expression in several inflammation-mediated diseases. In this review, we will outline the effects of pro-inflammatory cytokines in the pathogenesis of AKI and CKD. We also discuss the role of IL-20 in kidney diseases and provide a potential therapeutic approach of IL-20 blockade for treating renal diseases.
Targeting Age-Dependent Functional and Metabolic Decline of Human Skeletal Muscle: The Geroprotective Role of Exercise, Myokine IL-6, and Vitamin D
Authors: Crescioli Clara
Published: February 2020

In the elderly, whole-body health largely relies on healthy skeletal muscle, which controls body stability, locomotion, and metabolic homeostasis. Age-related skeletal muscle structural/functional deterioration is associated with a higher risk of severe comorbid conditions and poorer outcomes, demanding major socioeconomic costs. Thus, the need for efficient so-called geroprotective strategies to improve resilience and ensure a good quality of life in older subjects is urgent. Skeletal muscle senescence and metabolic dysregulation share common cellular/intracellular mechanisms, potentially representing targets for intervention to preserve muscle integrity. Many factors converge in aging, and multifaceted approaches have been proposed as interventions, although they have often been inconclusive. Physical exercise can counteract aging and metabolic deficits, not only in maintaining tissue mass, but also by preserving tissue secretory function. Indeed, skeletal muscle is currently considered a proper secretory organ controlling distant organ functions through immunoactive regulatory small peptides called myokines. This review provides a current perspective on the main biomolecular mechanisms underlying age-dependent and metabolic deterioration of skeletal muscle, herein discussed as a secretory organ, the functional integrity of which largely depends on exercise and myokine release. In particular, muscle-derived interleukin (IL)-6 is discussed as a nutrient-level biosensor. Overall, exercise and vitamin D are addressed as optimal geroprotective strategies in view of their multi-target effects.
Calmodulin-Binding Proteins in Muscle: A Minireview on Nuclear Receptor Interacting Protein, Neurogranin, and Growth-Associated Protein 43
Authors: Moradi Fereshteh , Copeland Emily N. , Baranowski Ryan W. , Scholey Aiden E. , Stuart Jeffrey A. , Fajardo Val A.
Published: February 2020

Calmodulin (CaM) is an important Ca2+-sensing protein with numerous downstream targets that are either CaM-dependant or CaM-regulated. In muscle, CaM-dependent proteins, which are critical regulators of dynamic Ca2+ handling and contractility, include calcineurin (CaN), CaM-dependant kinase II (CaMKII), ryanodine receptor (RyR), and dihydropyridine receptor (DHPR). CaM-regulated targets include genes associated with oxidative metabolism, muscle plasticity, and repair. Despite its importance in muscle, the regulation of CaM—particularly its availability to bind to and activate downstream targets—is an emerging area of research. In this minireview, we discuss recent studies revealing the importance of small IQ motif proteins that bind to CaM to either facilitate (nuclear receptor interacting protein; NRIP) its activation of downstream targets, or sequester (neurogranin, Ng; and growth-associated protein 43, GAP43) CaM away from their downstream targets. Specifically, we discuss recent studies that have begun uncovering the physiological roles of NRIP, Ng, and GAP43 in skeletal and cardiac muscle, thereby highlighting the importance of endogenously expressed CaM-binding proteins and their regulation of CaM in muscle.
Isolation and Identification of Ipomoea cairica (L.) Sweet Gene IcSRO1 Encoding a SIMILAR TO RCD-ONE Protein, Which Improves Salt and Drought Tolerance in Transgenic Arabidopsis
Authors: Yuan Benqi , Chen Minghao , Li Shaoshan
Published: February 2020

Ipomoea cairica is a tropical plant and a wild relative of the food plant sweet potato (Ipomoea batatas), listed as one of the most invasive alien species in China. Recently, it has been reported that I. cairica had successfully invaded mangrove wetlands, indicating its high salt tolerance. Based on previous genetic studies, I. cairica offers a good model for characterizing stress-resistant genes. It has recently been identified that the SRO proteins (SIMILAR TO RCD-ONE) play important roles in a variety of stress and developmental responses. Radical-Induced Cell Death1 (RCD1) was the first identified plant SRO protein from Arabidopsis thaliana. As a typical SRO protein, IcSRO1 had a highly conservative WWE domain, a conserved PARP fold and protein C in the RST function area. The expression of IcSRO1 was induced by salt, drought, and the plant hormone ABA. The transgenic Arabidopsis overexpressing IcSRO1 showed higher tolerance against salt and drought stress along with lower accumulation of hydrogen peroxide (H2O2) and superoxide (O2−) than the wild type. The IcSRO1 protein was localized in the nucleus after cultivation in the buffer. Our results indicated it could interact with Arabidopsis SALT OVERLY SENSITIVE 1 (AtSOS1), suggesting IcSRO1 may have similar functions. The pleiotropic effect of IcSRO1 on physiological processes contributes to the improvement of plant tolerance against diverse abiotic stresses, and may be associated with the adaptation of I. cairica to those environments with extreme saline and drought conditions. It therefore provides valuable gene resources for crop breeding enhancement.
Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation
Authors: Choi Eun-Jeong , Kil In Sup , Cho Eun-Gyung
Published: February 2020

The skin is a multilayered and primary defensive organ. Intimate intercellular communication in the skin is necessary to ensure effective surveillance. Extracellular vesicles (EVs) are being explored for their involvement in intercellular skin communication. The aim of this study was to evaluate how human dermal fibroblasts (HDFs) accelerate EV production during senescence and the effects of senescence-associated EVs on epidermal homeostasis. Replicative senescent HDFs were assessed with senescence-associated β-galactosidase staining and the expression of senescence-related markers. Isolated EVs were characterized by dynamic light scattering and EV marker expression. EVs secreted from untreated young or senescent HDFs, or from those treated with a nSMase inhibitor, antioxidant, and lysosomal activity regulators, were determined by sandwich ELISA for CD81. Human epidermal keratinocytes were treated with young- and senescent HDF-derived EVs. Compared to young HDFs, senescent HDFs produced relatively high levels of EVs due to the increased nSMase activity, oxidative stress, and altered lysosomal activity. The nSMase inhibitor, antioxidant, and agents that recovered lysosomal activity reduced EV secretion in senescent HDFs. Relative to young HDF-derived EVs, senescent HDF-derived EVs were less supportive in keratinocyte differentiation and barrier function but increased proinflammatory cytokine IL-6 levels. Our study suggests that dermis-derived EVs may regulate epidermal homeostasis by reflecting cellular status, which provides insight as to how the dermis communicates with the epidermis and influences skin senescence.
Ectopic Expression of Gs5PTase8, a Soybean Inositol Polyphosphate 5-Phosphatase, Enhances Salt Tolerance in Plants
Authors: Jia Qi , Sun Song , Kong Defeng , Song Junliang , Wu Lumei , Yan Zhen , Zuo Lin , Yang Yingjie , Liang Kangjing , Lin Wenxiong , Huang Jinwen
Published: February 2020

Inositol polyphosphate 5-phosphatases (5PTases) function in inositol signaling by regulating the catabolism of phosphoinositol derivatives. Previous reports showed that 5PTases play a critical role in plant development and stress responses. In this study, we identified a novel 5PTase gene, Gs5PTase8, from the salt-tolerance locus of chromosome 3 in wild soybean (Glycine soja). Gs5PTase8 is highly up-regulated under salt treatment. It is localized in the nucleus and plasma membrane with a strong signal in the apoplast. Ectopic expression of Gs5PTase8 significantly increased salt tolerance in transgenic BY-2 cells, soybean hairy roots and Arabidopsis, suggesting Gs5PTase8 could increase salt tolerance in plants. The overexpression of Gs5PTase8 significantly enhanced the activities of catalase and ascorbate peroxidase under salt stress. The seeds of Gs5PTase8-transgenic Arabidopsis germinated earlier than the wild type under abscisic acid treatment, indicating Gs5PTase8 would alter ABA sensitivity. Besides, transcriptional analyses showed that the stress-responsive genes, AtRD22, AtRD29A and AtRD29B, were induced with a higher level in the Gs5PTase8-transgenic Arabidopsis plants than in the wild type under salt stress. These results reveal that Gs5PTase8 play a positive role in salt tolerance and might be a candidate gene for improving soybean adaptation to salt stress.
Human Long Noncoding RNA Interactome: Detection, Characterization and Function
Authors: Kazimierczyk Marek , Kasprowicz Marta K. , Kasprzyk Marta E. , Wrzesinski Jan
Published: February 2020

The application of a new generation of sequencing techniques has revealed that most of the genome has already been transcribed. However, only a small part of the genome codes proteins. The rest of the genome "dark matter” belongs to divergent groups of non-coding RNA (ncRNA), that is not translated into proteins. There are two groups of ncRNAs, which include small and long non-coding RNAs (sncRNA and lncRNA respectively). Over the last decade, there has been an increased interest in lncRNAs and their interaction with cellular components. In this review, we presented the newest information about the human lncRNA interactome. The term lncRNA interactome refers to cellular biomolecules, such as nucleic acids, proteins, and peptides that interact with lncRNA. The lncRNA interactome was characterized in the last decade, however, understanding what role the biomolecules associated with lncRNA play and the nature of these interactions will allow us to better understand lncRNA's biological functions in the cell. We also describe a set of methods currently used for the detection of lncRNA interactome components and the analysis of their interactions. We think that such a holistic and integrated analysis of the lncRNA interactome will help to better understand its potential role in the development of organisms and cancers.
Human Pluripotent Stem Cells in Reproductive Science—A Comparison of Protocols Used to Generate and Define Male Germ Cells from Pluripotent Stem Cells
Authors: Kurek Magdalena , Albalushi Halima , Hovatta Outi , Stukenborg Jan-Bernd
Published: February 2020

Globally, fertility-related issues affect around 15% of couples. In 20%–30% of cases men are solely responsible, and they contribute in around 50% of all cases. Hence, understanding of in vivo germ-cell specification and exploring different angles of fertility preservation and infertility intervention are considered hot topics nowadays, with special focus on the use of human pluripotent stem cells (hPSCs) as a source of in vitro germ-cell generation. However, the generation of male germ cells from hPSCs can currently be considered challenging, making a judgment on the real perspective of these innovative approaches difficult. Ever since the first spontaneous germ-cell differentiation studies, using human embryonic stem cells, various strategies, including specific co-cultures, gene over-expression, and addition of growth factors, have been applied for human germ-cell derivation. In line with the variety of differentiation methods, the outcomes have ranged from early and migratory primordial germ cells up to post-meiotic spermatids. This variety of culture approaches and cell lines makes comparisons between protocols difficult. Considering the diverse strategies and outcomes, we aim in this mini-review to summarize the literature regarding in vitro derivation of human male germ cells from hPSCs, while keeping a particular focus on the culture methods, growth factors, and cell lines used.
Molecular Characterization and Disease Control of Stem Canker on Royal Poinciana (Delonix regia) Caused by Neoscytalidium dimidiatum in the United Arab Emirates
Authors: Al Raish Seham M. , Saeed Esam Eldin , Sham Arjun , Alblooshi Khulood , El-Tarabily Khaled A. , AbuQamar Synan F.
Published: February 2020

In the United Arab Emirates (UAE), royal poinciana (Delonix regia) trees suffer from stem canker disease. Symptoms of stem canker can be characterized by branch and leaf dryness, bark lesions, discoloration of xylem tissues, longitudinal wood necrosis and extensive gumming. General dieback signs were also observed leading to complete defoliation of leaves and ultimately death of trees in advanced stages. The fungus, Neoscytalidium dimidiatum DSM 109897, was consistently recovered from diseased royal poinciana tissues; this was confirmed by the molecular, structural and morphological studies. Phylogenetic analyses of the translation elongation factor 1-a (TEF1-α) of N. dimidiatum from the UAE with reference specimens of Botryosphaeriaceae family validated the identity of the pathogen. To manage the disease, the chemical fungicides, Protifert®, Cidely® Top and Amistrar® Top, significantly inhibited mycelial growth and reduced conidial numbers of N. dimidiatum in laboratory and greenhouse experiments. The described “apple bioassay” is an innovative approach that can be useful when performing fungicide treatment studies. Under field conditions, Cidely® Top proved to be the most effective fungicide against N. dimidiatum among all tested treatments. Our data suggest that the causal agent of stem canker disease on royal poinciana in the UAE is N. dimidiatum.
The Amuvatinib Derivative, N-(2H-1,3-Benzodioxol-5-yl)-4-{thieno[3,2-d]pyrimidin-4-yl}piperazine-1-carboxamide, Inhibits Mitochondria and Kills Tumor Cells under Glucose Starvation
Authors: Marciano Ran , David Hila Ben , Akabayov Barak , Rotblat Barak
Published: February 2020

Glucose levels inside solid tumors are low as compared with normal surrounding tissue, forcing tumor cells to reprogram their metabolism to adapt to such low glucose conditions. Unlike normal tissue, tumor cells experience glucose starvation, making the targeting of pathways supporting survival during glucose starvation an interesting therapeutic strategy in oncology. Using high-throughput screening, we previously identified small molecules that selectively kill cells exposed to glucose starvation. One of the identified compounds was the kinase inhibitor amuvatinib. To identify new molecules with potential antineoplastic activity, we procured 12 amuvatinib derivatives and tested their selective toxicity towards glucose-starved tumor cells. One of the amuvatinib derivatives, N-(2H-1,3-benzodioxol-5-yl)-4-{thieno[3,2-d]pyrimidin-4-yl}piperazine-1-carboxamide, termed compound 6, was found to be efficacious in tumor cells experiencing glucose starvation. In line with the known dependence of glucose-starved cells on the mitochondria, compound 6 inhibits mitochondrial membrane potential. These findings support the concept that tumor cells are dependent on mitochondria under glucose starvation, and bring forth compound 6 as a new molecule with potential antitumor activity for the treatment of glucose-starved tumors.
Evaluating Face2Gene as a Tool to Identify Cornelia de Lange Syndrome by Facial Phenotypes
Authors: Latorre-Pellicer Ana , Ascaso Ángela , Trujillano Laura , Gil-Salvador Marta , Arnedo Maria , Lucia-Campos Cristina , Antoñanzas-Pérez Rebeca , Marcos-Alcalde Iñigo , Parenti Ilaria , Bueno-Lozano Gloria , Musio Antonio , Puisac Beatriz , Kaiser Frank J. , Ramos Feliciano J. , Gómez-Puertas Paulino , Pié Juan
Published: February 2020

Characteristic or classic phenotype of Cornelia de Lange syndrome (CdLS) is associated with a recognisable facial pattern. However, the heterogeneity in causal genes and the presence of overlapping syndromes have made it increasingly difficult to diagnose only by clinical features. DeepGestalt technology, and its app Face2Gene, is having a growing impact on the diagnosis and management of genetic diseases by analysing the features of affected individuals. Here, we performed a phenotypic study on a cohort of 49 individuals harbouring causative variants in known CdLS genes in order to evaluate Face2Gene utility and sensitivity in the clinical diagnosis of CdLS. Based on the profile images of patients, a diagnosis of CdLS was within the top five predicted syndromes for 97.9% of our cases and even listed as first prediction for 83.7%. The age of patients did not seem to affect the prediction accuracy, whereas our results indicate a correlation between the clinical score and affected genes. Furthermore, each gene presents a different pattern recognition that may be used to develop new neural networks with the goal of separating different genetic subtypes in CdLS. Overall, we conclude that computer-assisted image analysis based on deep learning could support the clinical diagnosis of CdLS.
Stateless IoT
Authors: Ciuffoletti Augusto
Published: February 2020

Energy consumption is a relevant matter in the design of IoT applications. Edge units—sensors and actuators—save energy by operating intermittently. When idle, they suspend their operation, losing the content of the onboard memory. Their internal state, needed to resume their work, is recorded on external storage: in the end, their internal operation is stateless. The backend infrastructure does not follow the same design principle: concentrators, routers, and servers are always-on devices that frustrate the energy-saving operation of edge devices. In this paper, we show how serverless functions, asynchronously invoked by the stateless edge devices, are an energy-saving option. We introduce a basic model for system operation and energy footprint evaluation. To demonstrate its soundness, we study a simple use case, from the design to a prototype.
Sub-Antarctic Freshwater Invertebrate Thermal Tolerances: An Assessment of Critical Thermal Limits and Behavioral Responses
Authors: Rendoll-Cárcamo Javier , Contador Tamara , Convey Peter , Kennedy James
Published: February 2020

Physiological thermal limits of organisms are linked to their geographic distribution. The assessment of such limits can provide valuable insights when monitoring for environmental thermal alterations. Using the dynamic critical thermal method (CTM), we assessed the upper (CTmax) and lower (CTmin) thermal limits of three freshwater macroinvertebrate taxa with restricted low elevation distribution (20 m a.s.l.) and three taxa restricted to upper elevations (480 and 700 m a.s.l.) in the Magellanic sub-Antarctic ecoregion of southern Chile. In general terms, macroinvertebrates restricted to lower altitudinal ranges possess a broader thermal tolerance than those restricted to higher elevations. Upper and lower thermal limits are significantly different between taxa throughout the altitudinal gradient. Data presented here suggest that freshwater macroinvertebrates restricted to upper altitudinal ranges may be useful indicators of thermal alteration in their habitats, due to their relatively low tolerance to increasing temperatures and the ease with which behavioral responses can be detected.
Behavioral and Electrophysiological Effects of Ajowan (Trachyspermum ammi Sprague) (Apiales: Apiaceae) Essential Oil and Its Constituents on Nymphal and Adult Bean Bugs, Riptortus clavatus (Thunberg) (Hemiptera: Alydidae)
Authors: Lee Sung-Chan , Seo Seon-Mi , Huh Min-Jung , Kwon Jun-Hyeong , Nam Il , Park Ji-Hong , Park Il-Kwon
Published: February 2020

We investigated the repellent effect of 12 Apiaceae plant essential oils on nymphal and adult (male and female) forms of the bean bug, Riptortus clavatus (Thunberg) (Hemiptera: Alydidae), using a four-arm olfactometer. Among the essential oils tested, ajowan (Trachyspermum ammi Sprague) essential oil showed the strongest repellent activity against the nymphal and adult bean bugs. For female adults, the repellent activity was significantly different between an ajowan oil-treated chamber and an untreated chamber down to a concentration of 14.15 μg/cm2. We also investigated the repellent activity of individual ajowan essential oil constituents. Of the compounds examined, carvacrol and thymol showed the most potent repellent activity against the nymphal and adult bean bugs. Carvacrol and thymol exhibited 73.08% and 70.0% repellent activity for the bean bug nymph at 0.71 and 2.83 μg/cm2, respectively, and 82.6% and 80.7% at 5.66 and 11.32 μg/cm2, respectively, for male adults. Carvacrol and thymol exhibited strong repellent activity against female adult bean bugs down to a concentration of 2.83 μg/cm2. Ajowan essential oil, thymol and carvacrol elicited a negative electroantennogram (EAG) response from adult bean bugs. This could explain the repellent activity of ajowan essential oil and its constituents. Our results indicate that ajowan essential oil and its constituents carvacrol and thymol can be potential candidates as the ‘push’ component in a ‘push-pull’ strategy for bean bug control.
Thread Quality Control in High-Speed Tapping Cycles
Authors: Gil Del Val Alain , Veiga Fernando , Suárez Alfredo , Arizmendi Mikel
Published: February 2020

Thread quality control is becoming a widespread necessity in manufacturing to guarantee the geometry of the resulting screws on the workpiece due to the high industrial costs. Besides, the industrial inspection is manual provoking high rates of manufacturing delays. Therefore, the aim of this paper consists of developing a statistical quality control approach acquiring the data (torque signal) coming from the spindle drive for assessing thread quality using different coatings. The system shows a red light when the tap wear is critical before machining in unacceptable screw threads. Therefore, the application could reduce these high industrial costs because it can work self-governance.
A Method for Heterogeneous Spatio-Temporal Data Integration in Support of Marine Aquaculture Site Selection
Authors: Beard Kate , Kimble Melissa , Yuan Jing , Evans Keith S. , Liu Wei , Brady Damian , Moore Stephen
Published: February 2020

Aquaculture site selection, like most site suitability analyses, requires the assembly and combination of multiple variables. Geographic information systems GIS and multi-criteria evaluation (MCE) based approaches are commonly used for aquaculture site selection and demonstrate the integration of various information sources relevant for siting aquaculture. These analyses, however, tend to be one-time and result in a fixed site suitability plan. Within a dynamic marine environment experiencing potential regime shifts, a siting support tool that integrates new and evolving spatio-temporal data has benefits. This paper presents a flexible Voronoi cell-based GIS model for marine aquaculture siting. Rather than a one-time specification of suitable locations, the approach uses similarity measures on the characteristics of Voronoi cells to find cells with similar characteristics. We calculate a weighted aquaculture site tenure value for Voronoi cells that have been or are occupied by aquaculture farm sites. High scoring cells suggest suitable sites and serve as targets for similarity queries. We apply the approach to a case study on the coast of Maine using an R Shiny application to demonstrate the use of the framework for finding sites with similar characteristics.
First-Principles Study on Structural, Mechanical, Anisotropic, Electronic and Thermal Properties of III-Phosphides: XP (X = Al, Ga, or In) in the P6422 Phase
Authors: Miao Junjie , Chai Changchun , Zhang Wei , Song Yanxing , Yang Yintang
Published: February 2020

The structural, mechanical, electronic, and thermal properties, as well as the stability and elastic anisotropy, of XP (X = Al, Ga, or In) in the P6422 phase were studied via density functional theory (DFT) in this work. P6422-XP (X = Al, Ga, or In) are dynamically and thermodynamically stable via phonon spectra and enthalpy. At 0 GPa, P6422-XP (X = Al, Ga, or In) are more rigid than F 4 ¯ 3 m-XP (X = Al, Ga, or In), of which P6422-XP (X = Al or Ga) are brittle and P6422-InP is ductile. In the same plane (except for (001)-plane), P6422-AlP and P6422-InP exhibit the smallest and the largest anisotropy, respectively, and P6422-XP (X = Al, Ga, or In) is isotropic in the (001)-plane. In addition, Al, Ga, In, and P bonds bring different electrical properties: P6422-InP exhibits a direct band gap (0.42 eV) with potential application for an infrared detector, whereas P6422-XP (X = Al or Ga) exhibit indirect band gap (1.55 eV and 0.86 eV). At high temperature (approaching the melting point), the theoretical minimum thermal conductivities of P6422-XP (X = Al, Ga, or In) are AlP (1.338 W∙m−1∙K−1) > GaP (1.058 W∙m−1∙K−1) > InP (0.669 W∙m−1∙K−1), and are larger than those of F 4 ¯ 3 m-XP (X = Al, Ga, or In). Thus, P6422-XP (X = Al, Ga, or In) have high potential application at high temperature.
Comparative Study on Mechanical Properties of Sealing Grease Composed of Different Base Oils for Shield Tunnel
Authors: Li Xiangqian , Yang Yuyou , Li Fan
Published: February 2020

This study proposes a novel sealing grease with improved mechanical properties and environmental performance. A series of sealing grease samples were made with different base oils, including mineral oil and renewable oil (vegetable oil and lard). In this study, thermogravimetric analysis (TGA) was conducted to study the adsorption capacity of the thickener to the base oil. The fluidity of the sealing grease was also tested at different temperatures. Furthermore, an exponential function was proposed for the flow rate of the sealing grease and the temperature. Moreover, a cone penetration test was conducted to study the consistency of the sealing grease. The results indicated that the capacity of the thickener to adsorb vegetable oil was greater than that of mineral oil, but less than that of lard. Additionally, the flow rate of the sealing grease increased with an increase in temperature. At a fixed temperature, the flow rate of the sealing grease increased with the base oil content. According to the exponential function, the composition of the base oil is the key factor that determines the temperature sensitivity of the sealing grease. In addition, the sealing grease made of vegetable oil has the minimum temperature sensitivity coefficient.
Contacts for Molybdenum Disulfide: Interface Chemistry and Thermal Stability
Authors: Freedy Keren M. , McDonnell Stephen J.
Published: February 2020

In this review on contacts with MoS2, we consider reports on both interface chemistry and device characteristics. We show that there is considerable disagreement between reported properties, at least some of which may be explained by variability in the properties of geological MoS2. Furthermore, we highlight that while early experiments using photoemission to study the interface behavior of metal-MoS2 showed a lack of Fermi-level pinning, device measurements repeatedly confirm that the interface is indeed pinned. Here we suggest that a parallel conduction mechanism enabled by metallic defects in the MoS2 materials may explain both results. We note that processing conditions during metal depositions on MoS2 can play a critical role in the interface chemistry, with differences between high vacuum and ultra-high vacuum being particularly important for low work function metals. This can be used to engineer the interfaces by using thin metal-oxide interlayers to protect the MoS2 from reactions with the metals. We also report on the changes in the interfaces that can occur at high temperature which include enhanced reactions between Ti or Cr and MoS2, diffusion of Ag into MoS2, and delamination of Fe. What is clear is that there is a dearth of experimental work that investigates both the interface chemistry and device properties in parallel.
Evaluation of the Use of an Inorganic Bone Matrix in the Repair of Bone Defects in Rats Submitted to Experimental Alcoholism
Authors: Santos German Iris Jasmin , Pomini Karina Torres , Bighetti Ana Carolina Cestari , Andreo Jesus Carlos , Reis Carlos Henrique Bertoni , Shinohara André Luis , Rosa Júnior Geraldo Marco , Teixeira Daniel de Bortoli , Rosso Marcelie Priscila de Oliveira , Buchaim Daniela Vieira , Buchaim Rogério Leone
Published: February 2020

To assess the effects of chronic alcoholism on the repair of bone defects associated with xenograft. Forty male rats were distributed in: control group (CG, n = 20) and experimental group (EG, n = 20), which received 25% ethanol ad libitum after a period of adaptation. After 90 days of liquid diet, the rats were submitted to 5.0-mm bilateral craniotomy on the parietal bones, subdividing into groups: CCG (control group that received only water with liquid diet and the defect was filled with blood clot), BCG (control group that received only water with liquid diet and the defect was filled with biomaterial), CEG (alcoholic group that received only ethanol solution 25% v/v with liquid diet and the defect was filled with blood clot), and BEG (alcoholic group that received only ethanol solution 25% v/v with liquid diet and the defect was filled with biomaterial). In the analysis of body mass, the drunk animals presented the lowest averages in relation to non-drunk animals during the experimental period. Histomorphologically all groups presented bone formation restricted to the defect margins at 60 days, with bone islets adjacent to the BCG biomaterial particles. CEG showed significant difference compared to BEG only at 40 days (17.42 ± 2.78 vs. 9.59 ± 4.59, respectively). In the birefringence analysis, in early periods all groups showed red-orange birefringence turning greenish-yellow at the end of the experiment. The results provided that, regardless of clinical condition, i.e., alcoholic or non-alcoholic, in the final period of the experiment, the process of bone defect recomposition was similar with the use of xenograft or only clot.
Application of Sustainable Bamboo-Based Composite Reinforcement in Structural-Concrete Beams: Design and Evaluation
Authors: Javadian Alireza , Smith Ian F. C. , Hebel Dirk E.
Published: February 2020

Reinforced concrete is the most widely used building material in history. However, alternative natural and synthetic materials are being investigated for reinforcing concrete structures, given the limited availability of steel in developing countries, the rising costs of steel as the main reinforcement material, the amount of energy required by the production of steel, and the sensitivity of steel to corrosion. This paper reports on a unique use of bamboo as a sustainable alternative to synthetic fibers for production of bamboo fiber-reinforced polymer composite as reinforcement for structural-concrete beams. The aim of this study is to evaluate the feasibility of using this novel bamboo composite reinforcement system for reinforced structural-concrete beams. The bond strength with concrete matrix, as well as durability properties, including the water absorption and alkali resistance of the bamboo composite reinforcement, are also investigated in this study. The results of this study indicate that bamboo composite reinforced concrete beams show comparable ultimate loads with regards to fiber reinforced polymer (FRP) reinforced concrete beams according to the ACI standard. Furthermore, the results demonstrate the potential of the newly developed bamboo composite material for use as a new type of element for non-deflection-critical applications of reinforced structural-concrete members. The design guidelines that are stated in ACI 440.1R-15 for fiber reinforced polymer (FRP) reinforcement bars are also compared with the experimental results that were obtained in this study. The American Concrete Institute (ACI) design guidelines are suitable for non-deflection-critical design and construction of bamboo-composite reinforced-concrete members. This study demonstrates that there is significant potential for practical implementation of the bamboo-composite reinforcement described in this paper. The results of this study can be utilized for construction of low-cost and low-rise housing units where the need for ductility is low and where secondary-element failure provides adequate warning of collapse.
Repeated Exposure of Nanostructured Titanium to Osteoblasts with Respect to Peri-Implantitis
Authors: Babuska Vaclav , Kolaja Dobra Jana , Dluhos Ludek , Dvorakova Jana , Moztarzadeh Jana , Hrusak Daniel , Kulda Vlastimil
Published: February 2020

Titanium offers excellent biocompatibility and extraordinary mechanical properties. As a result, it is used as a material for dental implants. Implants infected by peri-implantitis can be cleaned for successful re-osseointegration. Optimal surface properties, such as roughness and wettability, have a significant impact on cell adhesion. The aim of this study was to evaluate the adhesion and proliferation of osteoblasts on the surface of repeatedly cleaned nanostructured titanium samples. Human osteoblast-like cells MG-63 were seeded on nanostructured titanium specimens manufactured from rods produced by the equal channel angular pressing. For surface characterization, roughness and wettability were measured. Cell adhesion after 2 h as well as cell proliferation after 48 h from plating was assessed. We have found that this repeated cleaning of titanium surface reduced cell adhesion as well as proliferation. These events depend on interplay of surface properties, such as wettability, roughness and topography. It is difficult to distinguish which factors are responsible for these events and further investigations will be required. However, even after the several rounds of repeated cleaning, there was a certain rate of adhesion and proliferation recorded. Therefore the attempts to save failing implants by using in situ cleaning are promising.
Numerical Testing of Switch Point Dynamics—A Curved Beam with a Variable Cross-Section
Authors: Kisilowski Jerzy , Kowalik Rafał
Published: February 2020

The article presents mathematical considerations on the dynamics of the springing switch point being an element of the railway junction. Due to the structure of the switch point, mathematical analysis was divided into two stages: The first stage refers to the analysis of the dynamics of the switch point as a beam of variable rectilinear stiffness to which three forces (coming from three closures of switch drives) placed in the initial section of the switch point are applied. The next stage of the analysis concerns an identical beam, but curved, with a variable cross-section. In both cases, the beam is subjected to a vertical force resulting from forces from the rail vehicle. The calculations refer to a switch point of 23 m length and a curvature radius R = 1200 m. The first stage of the switch point analysis refers to the movement of a rail vehicle on a straight track, and the second stage concerns the rail vehicle movement on a reverse path. This article also provides an analysis of mode vibrations of a curved beam with a variable cross-section, and variable inertia and stiffness moments (further in the article the changes will be referred to as beam parameter changes). It is assumed that the beam is loaded with vertical forces (coming) from a rail vehicle. The solution was found by applying the Ritz method, which served to present the fourth-order partial equations as ordinary differential ones. The numerical research whose results are given aimed to define how the changes in beam parameters and vertical load affect mode vibrations of the beam.
The Interfacial Characteristics of Graphene/Al4C3 in Graphene/AlSi10Mg Composites Prepared by Selective Laser Melting: First Principles and Experimental Results
Authors: Zhao Wenjie , Zhao Zhanyong , Bai Peikang , Zhang Lizheng , Han Bing , Du Wenbo
Published: February 2020

The Al4C3 phase was precipitated via a reaction of graphene (Gr) with Al during selective laser melting (SLM). The interfacial nature of the Gr (0001)/Al4C3 (0001) interface was determined using the first-principle calculation. The simulation results showed that the influence of the stacking site on the interfacial structure was limited and the Al-termination interface presented a more stable structure than the C-termination interface. The Al-termination-CH site interface had the largest work of adhesion (6.28 J/m2) and the smallest interfacial distance (2.02 Å) among the four interfacial structures. Mulliken bond population analysis showed that the bonding of the Al-termination interface was a mixture of covalent and ionic bonds and there was no chemical bonding in the C-termination interface.
The Effect of a Positive Cosmological Constant on the Bounce of Loop Quantum Cosmology
Authors: Martín-Benito Mercedes , Neves Rita B.
Published: February 2020

We provide an analytical solution to the quantum dynamics of a flat Friedmann-Lemaître- Robertson-Walker model with a massless scalar field in the presence of a small and positive cosmological constant, in the context of Loop Quantum Cosmology. We use a perturbative treatment with respect to the model without a cosmological constant, which is exactly solvable. Our solution is approximate, but it is precisely valid at the high curvature regime where quantum gravity corrections are important. We compute explicitly the evolution of the expectation value of the volume. For semiclassical states characterized by a Gaussian spectral profile, the introduction of a positive cosmological constant displaces the bounce of the solvable model to lower volumes and to higher values of the scalar field. These displacements are state dependent, and in particular, they depend on the peak of the Gaussian profile, which measures the momentum of the scalar field. Moreover, for those semiclassical states, the bounce remains symmetric, as in the vanishing cosmological constant case. However, we show that the behavior of the volume is more intricate for generic states, leading in general to a non-symmetric bounce.