bluuebunny/crossref_metadata_2025 huggingface dataset:
Strigolactones promote plant freezing tolerance by releasing the WRKY41‐mediated inhibition of CBF/DREB1 expression
Authors: Wang Xi , Li Zhuoyang , Shi Yiting , Liu Ziyan , Zhang Xiaoyan , Gong Zhizhong , Yang Shuhua
Published: August 2023

Cold stress is a major abiotic stress that adversely affects plant growth and crop productivity. The C‐REPEAT BINDING FACTOR/DRE BINDING FACTOR 1 (CBF/DREB1) transcriptional regulatory cascade plays a key role in regulating cold acclimation and freezing tolerance in Arabidopsis (Arabidopsis thaliana). Here, we show that max (more axillary growth) mutants deficient in strigolactone biosynthesis and signaling display hypersensitivity to freezing stress. Exogenous application of GR245DS, a strigolactone analog, enhances freezing tolerance in wild‐type plants and strigolactone‐deficient mutants and promotes the cold‐induced expression of CBF genes. Biochemical analysis showed that the transcription factor WRKY41 serves as a substrate for the F‐box E3 ligase MAX2. WRKY41 directly binds to the W‐box in the promoters of CBF genes and represses their expression, negatively regulating cold acclimation and freezing tolerance. MAX2 ubiquitinates WRKY41, thus marking it for cold‐induced degradation and thereby alleviating the repression of CBF expression. In addition, SL‐mediated degradation of SMXLs also contributes to enhanced plant freezing tolerance by promoting anthocyanin biosynthesis. Taken together, our study reveals the molecular mechanism underlying strigolactones promote the cold stress response in Arabidopsis.
Mefloquine targets NLRP3 to reduce lipopolysaccharide‐induced systemic inflammation and neural injury
Authors: Jiang Si‐Yuan , Tian Tian , Li Wen‐Jie , Liu Ting , Wang Cong , Hu Gang , Du Ren‐Hong , Liu Yang , Lu Ming
Published: August 2023

The NLR family pyrin domain containing 3 (NLRP3) inflammasome plays an important role in the pathogenesis of a wide variety of human diseases. So far, drugs directly and specifically targeting the NLRP3 inflammasome are not available for clinical use since the safety and efficacy of new compounds are often unclear. A promising approach is thus to identify NLRP3 inhibitors from existing drugs that are already in clinical use. Here, we show that mefloquine, a well‐known antimalarial drug, is a highly selective and potent NLRP3 inhibitor by screening a FDA‐approved drug library. Mechanistically, mefloquine directly binds to the NLRP3 NACHT and LRR domains to prevent NLRP3 inflammasome activation. More importantly, mefloquine treatment attenuates the symptoms of lipopolysaccharide‐induced systemic inflammation and Parkinson's disease‐like neural damage in mice. Our findings identify mefloquine as a potential therapeutic agent for NLRP3‐driven diseases and migth expand its clinical use considerably.
Discerning the supply chain of Bumiputera entrepreneurs in the Malaysian wood products and furniture industry: Status, challenges, and remedial measures
Authors: Amir Mohd. Afthar , Othman Kamaruzaman , Ratnasingam Jegatheswaran , Latib Hazirah Ab , Jegatheswaran Natkuncaran , Lim Choon Liat
Published: August 2023

Supply chain management has been identified as the major constraint on the growth of Bumiputera entrepreneurs in the Malaysian wood products and furniture sector. Therefore, a study to examine the characteristics of supply chain among Bumiputera entrepreneurs in the wood industry registered with the Malaysian Timber Industry Board was conducted. The results revealed that most of the respondents were micro- and small-sized enterprises, with a sales focus on the domestic and contract-market. They were predominantly wooden furniture manufacturers, who had a relatively low level of knowledge about supply chain management. The respondents also indicated that their major challenges include lack of finances, small volume of production, and the lack of government support. The factor analysis and regression analysis conducted revealed that for Bumiputera entrepreneurs to gain better supply chain management they need to improve their frequency of engagement, trust, culture, and maturity with their supply chain actors and partners. The results of this study are unique, as it implies that policymakers should take heed of improving supply chain management, to reverse the flagging fortune of Bumiputera entrepreneurs in the Malaysian wood products and furniture sector.
Cosmotécnicas para sair da crise contemporânea
Authors: Silva Maia Francisco Jadson , Lopes Almeida Luzia Cristina
Published: August 2023

Resenha do livro Tecnodiversidade (2020), de Yuk Hui. A obra apresenta os conceitos de tecnodiversidade e cosmotécnica que forjam saídas para a crise simultaneamente ecológica, política e social cristalizada hoje. A partir deles, a tecnologia como uma ideia universal é rejeitada. O intuito é desvelar que nenhuma tecnologia é neutra, mas sim intrinsicamente política, já que carrega consigo pressupostos epistemológicos e ontológicos que submete seus usuários. Em última instância, a crítica decolonial visa fomentar localmente a investigação de uma gama variada de tecnologias, que foram sendo retiradas de circulação pela universalização da técnica, imposta unilateralmente pelo Ocidente há um grande número de territórios com a modernidade e a globalização. Yuk Hui oferece às tecnologias modernas um novo marco filosófico, que enxerga na diversidade um futuro plural, inclusivo e diverso.
Limitações do uso da base de dados DATASUS como fonte primária de dados em pesquisas em cirurgia: uma revisão de escopo
Authors: VIANA SOFIA WAGEMAKER , FALEIRO MATHEUS DANIEL , MENDES ANNA LUIZA FONTES , TORQUATO AMANDA CIPRIANO , TAVARES CLARA PEREIRA OLIVEIRA , FERES BRENDA , FERNANDEZ MIGUEL GODEIRO , SOBREIRA ITALLO ROMERO MARQUES , AQUINO CAROLINE MARQUES DE , ABIB SIMONE DE CAMPOS VIEIRA , BOTELHO FABIO
Published: August 2023

RESUMO Objetivo: o DATASUS é o departamento do SUS responsável por disponibilizar dados de saúde que são empregados como fonte primária de dados em diversos estudos sobre cirurgia e especialidades cirúrgicas, embora principais limitações não tenham sido revisadas anteriormente. O objetivo deste trabalho é sintetizar as informações de estudos sobre cirurgia que utilizaram sistemas do DATASUS como fonte de dados, identificando as principais lacunas. Métodos: uma revisão de escopo foi conduzida de acordo com o método PRISMA-ScR para a identificação de trabalhos sobre cirurgia, e outras especialidade cirúrgicas, que utilizaram a plataforma DATASUS como fonte primária de dados. Nenhuma restrição foi imposta em relação ao tipo de estudo ou ano de publicação. A Teoria Fundamentada em Dados foi utilizada para a análise do conteúdo dos artigos. Resultados: 248 trabalhos foram inicialmente analisados e 47 foram incluídos na análise final deste estudo. Os artigos originais incluídos foram publicados entre 2009 e 2022, maioria (12,76%, n=6) foi publicada na Revista do Colégio Brasileiro de Cirurgiões. Estudos retrospectivos (40,43%, n=19) foram o tipo de estudo mais comum encontrado. A análise dos artigos identificou quatro domínios predominantes na literatura científica acerca das limitações do uso de DATASUS em pesquisas em cirurgia: falta de dados, confiabilidade, precisão e integralização dos dados. Conclusão: os sistemas de informação dispostos no DATASUS constituem a maior fonte de informações sobre o SUS, porém a literatura científica sobre a qualidade dos dados dispostos nestes sistemas permanece escassa e trabalhos direcionados a mensurar essa métrica são necessários.
Abdômen agudo em pacientes com covid-19: uma revisão integrativa
Authors: LIMA MANUELA IZIDIO DE , FONSECA NETO OLIVAL CIRILO LUCENA DA
Published: August 2023

RESUMO Introdução: a partir da infecção com o SARS-CoV-2, os pacientes apresentaram sintomas não clássicos, como fenômenos gastrointestinais que incluem perda de apetite, náuseas, vômitos, diarréia e dores abdominais. Essas ocorrências, normalmente, foram encontradas em pacientes gravemente afetados pelo COVID-19. Com isso, o objetivo deste trabalho é analisar o conhecimento disponível sobre o desenvolvimento do abdome agudo em pacientes infectados pelo SARS-CoV-2. Metodologia: trata-se de uma Revisão Integrativa na base de dados PubMed, Web of Science e BVS. Foi utilizado os descritores: “Acute abdomen”, “COVID-19”, “Abdominal pain” e “SARS-CoV-2” com o operador booleano “AND”, e selecionados artigos de relevância para o tema. Inicialmente, foram selecionados 331 artigos, todos publicados entre 2020 e 2023, em português e/ou inglês. Após análise, 11 artigos corresponderam ao objetivo proposto. Resultados: a relação entre a sensibilidade na região superior direita ou a presença do sinal de Murphy contribuiu na associação entre dor abdominal e as formas mais graves do COVID-19 em pacientes infectados. O número de diagnósticos para quadros agudos como colecistite, apendicite, diverticulite e pancreatite tiveram diminuição com a pandemia, mas ao mesmo tempo houve aumento na duração dos procedimentos cirúrgicos e nos períodos de internações. Esses quadros de abdome agudo foram resultados da procura tardia de assistência hospitalar que colaborou, inclusive no aumento da taxa de conversão para a cirurgia aberta e no número de quadros perfurativos. Conclusão: o desenvolvimento do abdome agudo em pacientes infectados pelo SARS-CoV-2 foi preditor de um prognóstico desfavorável.
Letramento digital e participação docente no Ensino Básico: uma discussão sobre relações com a extensão universitária
Authors: Santos Michelle Regina Alves dos , Amaral Marília Abrahão , Sales Márcia Barros de , Almeida Leonelo Dell Anhol
Published: August 2023

Resumo Ao compreender a participação enquanto processo de envolvimento e engajamento das pessoas em projetos com a comunidade, de maneira situada, compartilhando objetivos e ao entender a extensão universitária como troca de saberes, propomos neste artigo uma análise acerca do letramento digital docente. Para tanto, discutimos a participação de professoras em um projeto de extensão por meio dos marcadores extensão universitária e participação docente, provenientes de uma codificação temática, observando o pano de fundo, as interações entre as pessoas, as estratégias utilizadas e as consequências e resultados no projeto. O que foi constatado após a análise foi que a extensão universitária é um dos caminhos que promovem o letramento digital docente, por meio de projetos; que práticas participativas em projetos de extensão permitem que as pessoas sejam parte dos processos de desenvolvimento; e que nem sempre os projetos de extensão envolvem os professores e professoras no projeto como um todo.
Breast cancer and covid-19: reduction in diagnosis and treatment in a Hospital Unit in Pernambuco
Authors: Silva Rosalva Raimundo da , Lyra Tereza Maciel , Luna Carlos Feitosa , Pedroza Robervam de Moura , Albuquerque Emídio Cavalcanti de , Brito Ana Maria de
Published: August 2023

Abstract Objectives: to analyze the impact of the covid-19 pandemic on screening, diagnosis and treatment of breast cancer in Pernambuco, Northeastern Brazil. Method: cross-sectional study, based on secondary data from consultations with a mastologist, ultrasound, mammogram, biopsies, new cases, chemotherapy, radiotherapy and surgery, carried out in women for the screening, diagnosis and treatment of breast cancer, from January to December of the years 2019 to 2021. Results: the covid-19 pandemic reduced consultations with mastology (46.3%), ultrasounds (34.8%), mammogram (41.5%), biopsy (49.6%), new cases 45.7 % and surgery 34.6% in 2020 compared to 2019. On the other hand, with the exception of consultations with a mastologist and surgeries, all services where a significant reduction was observed in 2020, increased significantly in 2021 and returned to the same level of production in the pre-pandemic period. The pandemic did not negatively affect the supply of chemotherapy and radiotherapy. Conclusions: the findings of this study indicate negative impacts on breast cancer care, due to covid-19, during the first year of the pandemic, especially in consultations with a mastologist and surgery, which continued with low production in 2021. It is reasonable to assume that the reduction observed in procedures may reflect an increase in late diagnoses and a higher mortality rate in the coming years
Morphophysiology of soursop under salt stress and H2O2 application in the pre-flowering phase
Authors: Capitulino Jessica D. , Lima Geovani S. de , Azevedo Carlos A. V. de , Silva André A. R. da , Soares Lauriane A. dos A. , Arruda Thiago F. de L. , Sousa Vitória D. de , Gheyi Hans R.
Published: August 2023

ABSTRACT In the semi-arid region of the Brazilian Northeast, water sources generally have high levels of salts, standing out as one of the abiotic stresses that restrict the growth and development of plants. In this context, the objective of the present study was to evaluate the effects of foliar applications of hydrogen peroxide on the morphophysiology of soursop under salt stress in the pre-flowering phase. The experiment was carried out in a greenhouse, using a randomized block design and a 4 × 4 factorial arrangement, with four values of electrical conductivity of the irrigation water - ECw (0.8, 1.6, 2.4, and 3.2 dS m-1) and four concentrations of hydrogen peroxide - H2O2 (0, 10, 20, and 30 μM), with three replicates. An increase in water electrical conductivity from 0.8 dS m-1 reduced stomatal conductance, CO2 assimilation rate, instantaneous carboxylation efficiency, and leaf water saturation deficit. It inhibited the growth of soursop plants at 370 days after transplanting. Hydrogen peroxide at concentrations of up to 10 μM increased leaf transpiration and water use efficiency of soursop plants irrigated with 1.8 dS m-1 water in the pre-flowering phase.
Environmental, social and governance e o ciclo de vida das firmas: evidências no mercado brasileiro
Authors: Moreira Caritsa Scartaty , Araújo Jaqueline G. R. de , Silva Gilson Rodrigues da , Lucena Wenner Glaucio Lopes
Published: August 2023

RESUMO O estudo analisou a associação entre o environmental, social and governance (ESG) e os estágios de ciclo de vida das empresas brasileiras de capital aberto listadas na B3 S.A. - Brasil, Bolsa, Balcão (B3) no período de 2010 a 2020. Explora-se uma lacuna teórica sobre a relação dos estágios de ciclo de vida das empresas com iniciativas ESG no Brasil, um país emergente. As evidências são relevantes para a compreensão de como os estágios do ciclo de vida funcionam como sinalizadores do nível de ações ESG das companhias e para demonstrar como o mercado percebe essas ações e sua capacidade de geração de valor. A pesquisa traz insights de que os fundamentos da teoria dos estágios de ciclo de vida da firma funcionam como indicadores para diversas perspectivas organizacionais, até mesmo para as práticas ESG. A amostra foi composta por 109 empresas cujos dados foram coletados na Thomson Reuters® e analisados por meio de regressão múltipla. Para análise dos ciclos de vida, utilizou-se o modelo proposto por Dickinson (2011). Cabe destacar que os dados também foram analisados utilizando o efeito fixo como estimação do modelo econométrico, porém houve perda da significância estatística na relação encontrada, possivelmente devido à seleção da amostra realizada no painel desbalanceado. A partir da amostra analisada e dos modelos econométricos utilizados, os resultados indicam que as empresas em estágio de nascimento e turbulência apresentam menores níveis de práticas ESG, notadamente nos pilares ambiental e social, se comparadas às empresas em estágio de maturidade. Os achados também evidenciaram que as iniciativas ESG no mercado de capitais brasileiro estão associadas com medidas de rentabilidade, liquidez, endividamento, valor de mercado e número de analistas das organizações. A pesquisa contribui para a análise da associação entre a adoção de práticas ESG e os estágios de ciclo de vida das empresas em um mercado emergente, com reflexões aos stakeholders a respeito do direcionamento de recursos em ações sustentáveis.
Inspiratory muscle training in people with chronic obstructive pulmonary disease (COPD): a systematic review
Authors: Mota Jennyfer Correa , Santos Marcilene Rodrigues dos , Sousa Luane Rodrigues de , Abdoral Patrick Roberto Gomes , Abdoral Larissa Siqueira Rodrigues , Miranda Cláudia Jeane Claudino de Pontes
Published: August 2023

ABSTRACT This systematic review aimed to demonstrate the effectiveness of inspiratory muscle training (IMT) in people with chronic obstructive pulmonary disease (COPD), analyzing the effects of IMT on inspiratory muscle strength and endurance, exercise tolerance and reduction of dyspnea. A systematic search was carried out in the PubMed, Cochrane and Lilacs databases, from August 2021 to February 2023, searching for studies published from 2016. The descriptors used for the search followed the description of the MeSH/DeCS terms, namely: “Pulmonary Disease, Chronic Obstructive,” “Breathing Exercises,” “Exercise Tolerance,” “Dyspnea,” and “Muscle strength,” with the languages: English and Portuguese, using the Boolean operators “AND” and “OR.” Ten studies met the inclusion criteria, including 733 patients. In all examined studies, there was a significant increase in inspiratory muscle strength and endurance compared to the control group; of the ten studies analyzed, four showed advances in reducing dyspnea and exercise tolerance. Notably, inspiratory muscle training is effective in improving dyspnea, exercise tolerance, and in increasing inspiratory muscle strength and endurance in people with moderate to severe COPD.
Fatores associados ao tempo de decisão para procurar atendimento em face ao acidente vascular cerebral isquêmico
Authors: Muniz Ludimila Santos , Moraes Mariana de Almeida , Sales Rilary Silva , Ribeiro Laís Silva , Cunha Brenda Silva , Jesus Pedro Antônio Pereira de , Sampaio Elieusa e Silva , Baccin Camila Rosalia Antunes , Teles Carlos Antônio de Souza , Mussi Fernanda Carneiro
Published: August 2023

RESUMO Objetivo: Verificar a associação entre fatores sociodemográficos, clínicos, ambientais, cognitivos e emocionais e o tempo de decisão de pessoas com acidente vascular cerebral isquêmico para procurar um serviço de saúde após o início dos sintomas ou Wake up stroke Método: Estudo transversal realizado de março a outubro de 2019, com 304 pacientes, em hospital público, referência em neurologia. Dados obtidos por entrevista e no prontuário. O tempo de decisão foi analisado em média geométrica. Nas análises bivariadas e multivariada foi usada a regressão linear e o Critério de Informação de Akaike foi usado na seleção do melhor modelo. Adotou- se significância estatística de 5% Resultados: A média geométrica do tempo de decisão foi de 0,30h (IC 95% 0,23-0,39). O modelo final explicou em 41% esse tempo, mostrando aumento de 0,5 min para pessoas com hipertensão arterial; 10,8 min para quem esperou os sintomas melhorarem; 1,4 min para quem estava sozinho no início dos sintomas; 3,9 min para quem estava em casa; 3,2 min no trabalho e 2,1 na rua/via pública Conclusão: A média do tempo de decisão para procura de serviço de saúde foi alta e influenciada por variáveis clínicas, ambientais, cognitivas e emocionais. Os resultados orientam enfermeiros para a educação em saúde.
Da teoria à prática: a inclusão da família de crianças hospitalizadas nos procedimentos dolorosos
Authors: Souza Danton Matheus de , Fernandes Rafaela de Fátima , Costa Cibelle Tiphane de Sousa , Borghi Camila Amaral , Rossato Lisabelle Mariano
Published: August 2023

RESUMO Objetivo: Compreender as estratégias dos profissionais da equipe de enfermagem para a inclusão da família nos procedimentos dolorosos realizados em crianças hospitalizadas. Método: Estudo exploratório-descritivo, qualitativo, realizado com profissionais de enfermagem. Os dados foram coletados por meio de entrevistas semiestruturadas, guiadas por um roteiro de tópicos, transcritas e submetidas à análise temática de conteúdo, à luz do Interacionismo Simbólico, discutidas frente aos pressupostos da filosofia do Cuidado Centrado na Família. Resultados: Emergiram-se duas categorias centrais, “Perspectiva teórica: a família como agente de cuidado nos procedimentos dolorosos” e “Perspectiva prática: vivências, desafios e estratégias nos procedimentos dolorosos para inserção da família”, com suas respectivas subcategorias. Conclusão: Os profissionais de enfermagem possuem conhecimento teórico sobre a inclusão da família no procedimento doloroso com base nos pressupostos: Cuidado Centrado na Família: dignidade e respeito; compartilhamento de informações; participação conjunta; e colaboração da família. No entanto, os conhecimentos não são aplicados na prática clínica; consequência da interação entre as crenças e atitudes desfavoráveis à presença da família.
Parental educational practices, emotional health and maternal sociodemographic variables: Nuclear and non-nuclear families
Authors: Nogueira Sária Cristina , Rodrigues Olga Maria Piazentin Rolim , Pereira Veronica Aparecida
Published: August 2023

Abstract Objective We compared parental educational practices and emotional health of 62 mothers of students from nuclear (G1) and non-nuclear families (G2). Method We used an inventory of parenting practices and scales for assessment of anxiety, stress and depression. Results G1 showed significantly higher means for Moral Behavior. Positive correlations between negative parenting educational practices and clinical indicators for maternal emotional health were perceived in both groups and more significantly for G2. Younger mothers in G1 indicated more signs of state anxiety and for G2 the lower socioeconomic level indicated more signs of stress and trait anxiety and less depression. Conclusion The data can contribute to the planning of interventions.
Burnout at the hospital: Healthcare workers coping with COVID-19 stress
Authors: Freitas Maria Fernanda Marciano Barros de , Enumo Sônia Regina Fiorim , Machado Wagner de Lara , Messias João Carlos Caselli , Mendes Elisa Donalísio Teixeira
Published: August 2023

Abstract Objective The first wave of COVID-19 was challenging for healthcare workers. This study analyzed the ways of coping with stress at a university hospital. Method A Sociodemographic Characterization, Risk and Exposure Assessment, Burnout Assessment Tool (BAT-23), and COVID-19 Coping Scale were responded online by 181 professionals. Results The sample was composed mainly of women, white, married, physicians, with one job. Over 80% of the sample were at high exposure and risk for infection, with 17.1% having tested positive. The most reported stressors were risks of transmitting the disease, being hospitalized, and being separated from loved ones; 11% presented the risk of/probable burnout, with exhaustion and emotional impairment. They presented adaptive coping strategies, such as problem-solving and information-seeking, with a negative correlation between adaptive coping and burnout. Being a physician with maladaptive coping, in psychiatric care, and having religious beliefs were predictors of burnout. Conclusion Promoting adaptive coping may improve the mental health of these workers.
Multivariate analysis as a tool in the selection of sustainable melon agroecosystems in the semi-arid region
Authors: Salviano Alessandra M. , Castro José M. da C. , Melo Stefeson B. de , Macedo Márcia V. de , Oliveira Vitória R. , Giongo Vanderlise
Published: August 2023

ABSTRACT Soil management systems, including tillage and green manuring, are important for the control of nematodes and for the sustainable production. The objective was to select, through multivariate analysis, sustainable agroecosystems for yellow melon cultivated under irrigated conditions in the Brazilian semi-arid region. The long-term experiment is set up in Argissolo Vermelho- Amarelo (Ultisol) with six multifunctional agroecosystems, composed of the combination of three mixtures of cover crops (1 - 75% legumes + 25% grasses and oilseeds; 2 - 25% legumes + 75% grasses and oilseeds and 3 - spontaneous vegetation) and two types of soil management (no tillage-NT and tillage-T). The purpose was to evaluate the nutritional status of plants, soil fertility, nematode population in roots and soil, and the yield. Data were analyzed with multivariate techniques, allowing the grouping of the agroecosystems based on their similarities and complexity of functions. The incorporation of plant residues to the soil reduces nematode population, but their maintenance on the surface allows the improvement of fertility and yield, even under larger nematode populations. The agroecosystems that associate the nonincorporation of residues from cover crops with larger species diversity in composition constitute the most complex model, allowing different environmental functionalities. Thus, it is recommended not to incorporate the plant residues, planting the melon seedlings directly in the straw. However, considering that the results obtained with the non-incorporation of spontaneous vegetation were similar to those obtained with the incorporation of commercial cover crops, it is concluded that this practice is also viable and adapted to the semi-arid conditions.
Spatial variability of water electrical conductivity in underground dam areas in the semi-arid region of Rio Grande do Norte, Brazil
Authors: Chianca Cibele G. C. , Batista Rafael O. , Melo Stefeson B. de , Dias Nildo da S. , Matos Maria de F. A. de
Published: August 2023

ABSTRACT Underground dams have been widely deployed in the semi-arid region of Rio Grande do Norte, a state in the Brazilian Northeast, aiming to mitigate the effects caused by water scarcity. In this study, the geographic distribution of the electrical conductivity of water of underground dams was evaluated at the end of the dry season of 2018 and at the end of the rainy season of 2019. Maps were created in ArcGIS 10.4.1 software using the Inverse Distance Weighted interpolator. The results indicated high electrical conductivity variability in the evaluated underground dams. The highest values were obtained in the eastern portion of the Rio Grande do Norte state, except for two dams, located in the municipalities of Apodi and Severiano Melo. In most of the underground dams (64%), the water has an electrical conductivity with low soil salinization potential (EC < 0.7 dS m-1). It was observed that the salinity of the underground dams is influenced by several factors, such as climate, relief, land use and occupation due to rural agglomerations and animal husbandry in the dam hydrographic basin, and intensive nutritional management with fertilizers in the dam area.
Formation of guava seedlings under irrigation with water of different cationic natures and salicylic acid
Authors: Queiroga Claudiene M. de , Lima Geovani S. de , Torres Rafaela A. F. , Paiva Francisco J. da S. , Soares Lauriane A. dos A. , Gheyi Hans R.
Published: August 2023

ABSTRACT The objective of this study was to evaluate gas exchange, biomass, and quality of guava seedlings as a function of the cationic nature of the water used in irrigation and foliar application of salicylic acid. The experiment was carried out in a greenhouse in Pombal, PB, Brazil, using a randomized block design, in a 6 × 4 factorial scheme with six cationic compositions of irrigation water [S1 - Control (supply water); S2 - Na+; S3 - Ca2+; S4 - Na++Ca2+; S5 - Mg2+, and S6 - Na++Ca2++Mg2+], associated with four concentrations of salicylic acid (0, 1.3, 2.6, and 3.9 mM), with 3 replicates. Plants in control (S1) were irrigated with water of electrical conductivity (ECw) of 0.3 dS m-1, while in the other treatments were irrigated with different types of water and had an ECw of 4.3 dS m-1, consisting of different cations, in the form of chloride. In the seedling formation phase, guava plants were sensitive to calcic water, which resulted in a marked decrease in their growth. Stomatal conductance, transpiration, and biomass accumulation of guava seedlings were more affected by variation in electrical conductivity than by cationic nature of the water. Salicylic acid at concentrations of 2.9 and 1.9 mM increased stomatal conductance and stem dry biomass, respectively, of guava seedlings. Water with ECw of 4.3 dS m-1 allowed the formation of guava seedlings with acceptable quality for transplanting to the field, regardless of the cationic nature of the water.
Interactions between ants and mealybugs in sugarcane: species and effects on insect pests
Authors: Marchiori Johnatan J. de P. , Almeida Fábio S. de , Mayhé-Nunes Antônio J. , Nobre Rafael V. L. , Paulo Hágabo H. de
Published: August 2023

ABSTRACT The objective of this work was to evaluate ant species interacting with mealybugs in sugarcane plantations, the frequency of occurrence, and the effects of the interaction with ants on mealybug population size. The data was collected in a sugarcane plantation area in Seropedica, Rio de Janeiro, Brazil. The insect species were collected from 70 thoroughly inspected sugarcane plants and the nature and frequency of the interactions were evaluated. The effect of the interaction with ants on mealybug abundance was evaluated by counting the number of adult females of each mealybug species on ten plants isolated and ten plants not isolated from ants. Two mealybug species were collected: Aclerda takahashii (Kuwana, 1932) and Saccharicoccus sacchari (Cockerell, 1895). Ten and seven ant species were found interacting with A. takahashii and S. sacchari, respectively, which were distributed among six genera; the most frequent genera were Crematogaster and Camponotus. Three ant species interacted exclusively with A. takahashii, whereas the others interacted with both mealybug species. The abundance of A. takahashii females was significantly higher on non-isolated than on isolated plants (Paired t-test; t = 2.34; p = 0.04). However, no significant difference in S. sacchari abundance was found between isolated and non-isolated plants (t = 0.27; p = 0.8), nor for the two species combined (t = 1.9; p = 0.09). Thus, ant species that interact with mealybugs in sugarcane plantations cause increases in A. takahashii populations which, at a larger scale, can reduce crop yield.
Evaluation of newborn screening in the state of Mato Grosso from 2005 to 2019
Authors: Costa Roseli Divino , Ferreira Maria de Fátima de Carvalho , Rocha Thaís de Almeida , Galera Marcial Francis
Published: August 2023

ABSTRACT Objective: To evaluate quality indicators of the Neonatal Screening Referral Service of the state of Mato Grosso (NSRS-MT) from 2005 to 2019. Methods: Cross-sectional, retrospective, exploratory, descriptive, and observational study from 2005 to 2019. The following parameters were analyzed: age of newborns at the first collection, time between sample collection and arrival at the laboratory, time between the arrival and release of results and time between requesting the second sample and arrival at the NSRS. The population coverage of the program and the incidence of each clinical situation screened were also analyzed. Results: NSRS-MT coverage was analyzed and recorded as 76%. The incidence was analyzed for congenital hypothyroidism (CH) 1:1867, phenylketonuria (PKU) 1:33,311, sickle cell disease (SCD) 1:2004, cystic fibrosis (CF) 1:12,663, congenital adrenal hyperplasia (CAH) 1:15,843, and biotinidase deficiency (DB) 1:25,349. The median age (days) at the first consultation was: 44 for HC, 22 for PKU, 60 for DF, 52 for FC, 79 for HAC and 79 for DB. The mean time between exam collection and delivery to the NSRS was 8.4 days; between the arrival and release of results, 9 days; and for the return of recalls, 59 days. Conclusions: Regarding the coverage of the target population and collection at the ideal age, the NSRS-MT presents values below the national average. However, regarding the mean age at the time of the first consultation, the state's performance is better than the national.
Prenatal, neonatal and postnatal factors and the developmental defects of dental enamel
Authors: Lunardelli Sandra Espíndola , Lunardelli Abelardo Nunes , Martins Luiz Gustavo Teixeira , Traebert Eliane , Traebert Jefferson
Published: August 2023

ABSTRACT Objective: To estimate the prevalence of developmental defects in dental enamel and its possible association with prenatal, neonatal and postnatal conditions in six-year-old schoolchildren in a southern Brazilian municipality. Methods: A cross-sectional study was conducted involving 655 six-year-old schoolchildren. Sociodemographic and health data were collected through interviews with mothers and children’s oral examinations at schools. Multivariate analyses were performed using Poisson regression with robust estimator. Results: The prevalence of developmental defects of enamel was 44.0%. Demarcated opacities were the most prevalent, followed by diffuse opacities. Late pregnancy, maternal schooling less than eight years, female gender and child’s white skin color were independently associated with the prevalence of demarcated opacities. Conclusions: The prevalence of developmental defects in dental enamel was 44.0%. Late pregnancy, maternal schooling less than eight years, female gender and child’s white skin color were associated with the prevalences.
Los philosophes, los antiphilosophes y la opinión pública en Francia hacia 1760
Authors: Martínez Víctor Cases
Published: August 2023

RESUMEN En 1760 Palissot estrena Les philosophes, una comedia que expone dos problemas que preocupan a los antiphilosophes y a los enciclopedistas: está muy de moda hacerse llamar philosophe, aunque no se merezca tal denominación; quienes se jactan de entregarse de manera altruista a la batalla contra los prejuicios de la época emplean las artimañas más viles contra sus semejantes para lograr la codiciada plaza o el aplauso del público al que creen poder manipular a su antojo. Mediante el análisis de los textos en torno a la figura del philosophe en la Francia del siglo XVIII, y en particular los que alertan contra el deterioro de su imagen pública motivado por las querellas literarias, el artículo rescata fuentes que apenas han sido estudiadas, que resultan decisivas para comprender cómo los hombres de letras se perciben a sí mismos y valoran su ascendencia social sobre la multitud iletrada, despreciada tan a menudo. Desde esta perspectiva, el philosophe aparece como una figura polémica que se postula como el director de la opinión pública.
Harlequin Companies: the retrieval of a forgotten popular tradition in the fairs of Lisbon
Authors: Magalhães Paula Gomes
Published: August 2023

ABSTRACT In Lisbon, the fairs and their amusements were one of the most popular manifestations of popular culture during the second half of the 19th century and the beginning of the 20th century. Among the entertainment on offer, theater was one of the most appreciated, but history has only kept the memory of the shacks that, in the fairs, began to feature a recited repertoire (comedies, parodies, magic and revues). The tents of harlequins and saltimbancos, itinerant troupes that went from place-toplace performing acrobatics, pantomimes, and comic sketches, were forgotten. This article aims to highlight popular theater practices that were once ‘forgotten’, such as the troupes of harlequins and their shows, redefining their importance in the context of the time and the history of theater in Portugal.
Flavor and color: ‘IAC 134 AL01’, the Campinas Agronomic Institute’s first orange-colored pulp sweet potato cultivar
Authors: Peressin Valdemir Antonio , Feltran José Carlos , Rós Amarílis B , Bernacci Luís Carlos , Piotto Fernando Angelo , Factor Thiago Leandro , Lima Junior Sebastião de , Fabri Eliane G
Published: August 2023

ABSTRACT The sweet potato cultivar ‘IAC 134 AL01’ has tuberous roots with high β-carotene content, with the fresh pulp having an intermediate orange colour (based on international descriptors for the crop), which turns bright orange after cooking, and a mildly sweet taste. These roots have a long-irregular shape, red skin and are of medium size, weighing, on average, 300 g and measuring 14 x 6 cm. The first biofortified sweet potato cultivar of the Campinas Agronomic Institute reaches an average yield of 43.9 t/ha and is recommended for planting in the state of São Paulo to supply the domestic market and for export.
Morphological characters contributing to yield increase of potato cultivars in Brazil
Authors: Kawakami Jackson , Eschemback Vlandiney , Matos Cinthia K de , Melo Paulo Eduardo de
Published: August 2023

ABSTRACT A previous study revealed that modern potato cultivars used in Brazil have higher commercial tuber yield than old cultivars. The objective of the present study was to clarify which morphological characters influence the yield gain of modern cultivars. Two field experiments were performed in Brazil: in Guarapuava-PR and Brasilia-DF. The treatments consisted of six cultivars, classified according to origin and year of release: Bintje (European, 1910), Baronesa (Brazilian, 1955), Monalisa (European, 1982), Agata (European, 1990), Catucha (Brazilian, 1995) and BRS Clara (Brazilian, 2010). These were the main cultivars used in southern Brazil in the last 65 years and represent 100 years of breeding. A randomized complete block design with six treatments and four replications was used. The following plant morphological characters were evaluated at four growth stages (the beginning of plant development, the beginning of tuberization, maximum shoot growth and tuber bulking stages): leaf area index, specific leaf area, number of main stems, initiated and bulked tubers. At 15 days after emergence, modern cultivars have higher leaf area index and bulked tubers compared to older cultivars. Also, a larger number of mainstems and smaller specific leaf area were observed in modern cultivars. A high leaf area index at the beginning of the growing development combined with a large number of bulked tubers contributed to the increase of the yield potential of modern cultivars.
Hydraulic behavior of valves used in building water supply systems
Authors: Nhamussua Sheilla Maida Sergio , Thebaldi Michael Silveira , Lima Elvis Marcio de Castro , Fiais Pâmela Rodrigues , Silva Mateus Alexandre da , Deus Fábio Ponciano de
Published: August 2023

ABSTRACT This study was developed with the objective of evaluating the steady-state hydraulic behavior of gate, ball, and pressure valves with nominal diameters of ½” and ¾”, which are widely used in building water supply networks in Brazil. For this purpose, tests were performed to determine the head loss in ten different valves in four openings with five replicates. A hydraulic head loss testing apparatus was set up in a pipeline network that allowed for the control, monitoring, and acquisition of data. Mean values of the K coefficient of the minor head loss and the equivalent length were estimated for the conditions evaluated. The results were analyzed using box plots, correlation, principal components analysis, and hierarchical clustering. In general, the gate valves showed lower head loss for all the relative openings considered, while the pressure valves showed the greatest head loss. Of the clusters formed, for the second group, there was a predominance of treatments with pressure valves, which showed similarity in terms of the values of the hydraulic variables due to the geometry and construction of the valves.
Segurança hídrica para abastecimento urbano perante condições ambientais e qualidade da água do manancial: o caso da ETA Guandu, RMRJ
Authors: Paula Iero Xavier de , Formiga-Johnsson Rosa Maria
Published: August 2023

RESUMO Este trabalho avalia o nível de segurança hídrica quanto ao abastecimento de água da região oeste metropolitana do Rio de Janeiro, em termos de qualidade dos recursos hídricos no ponto de captação da estação de tratamento de água (ETA) Guandu, perante estressores envolvendo as condições ambientais e a qualidade das águas do manancial. Buscou-se ressaltar, de forma sistêmica, as principais questões de segurança hídrica, no que tange à qualidade de água bruta, na bacia drenante à ETA Guandu, responsável pelo atendimento de 75% da população metropolitana (8,5 milhões de pessoas). A área de estudo compreende essencialmente a bacia do rio Guandu a montante do ponto de captação da ETA. Foi aplicado um modelo analítico de avaliação qualitativa de segurança hídrica, adaptado ao caso da ETA Guandu, associado aos estressores: uso e cobertura da terra, degradação de área de preservação permanente, processos erosivos, acidentes ambientais e carga poluidora. Na sequência, os impactos foram caracterizados por meio dos indicadores de comprometimento da qualidade das águas do Rio Guandu: índice de qualidade de água; percentual de amostras em desconformidade com enquadramento; e registro de poluentes emergentes. Com resultados apontando alto risco para a maior parte dos estressores, concluiu-se ser baixo o nível global de segurança hídrica da ETA Guandu, em termos de qualidade de água bruta. Os problemas relacionados à Lagoa do Guandu são particularmente os mais graves, não somente pela poluição crônica agravada ao longo das décadas, mas sobretudo pela intensa poluição aguda que provocou crises hídricas sem precedentes em 2020 e 2021.
THE EFFECT OF LIQUID PROPERTIES ON HEAT TRANSFER AND EVAPORATION CHARACTERISTICS OF THE LIQUID FILMS FORMED BY UNSTEADY SPRAY-WALL IMPACTS
Authors: Jowkar Saeed , Shen Xing , Morad Mohammad Reza , Zeraatkardevin Amirhooshang
Published: August 2023

For intermittent spray-cooling purpose, it is essential to study the unsteady aspects of film evaporation and heat-transfer characteristics. In the present study, total evaporation time and surface temperature variations are investigated for four different liquid films (water, ethanol, n-octane, and n-hexane). The evaporation process is analyzed using a three-dimensional spray-wall impact with
Lagrangian wall-film model. The evaporation process occurs in three stages; at the initial moments, most of the heat is used to raise the film temperature, and slight evaporation also exists. The film temperature rises until it reaches the liquid saturation point to evaporate at a constant rate. In the last stage, the evaporation rate decreases with time due to the accumulation of vapor in the bulk flow. The
effect of heat flux and initial film thickness on the total evaporation time and the slope of its changes are investigated. The results show that the total evaporation time increases linearly with the initial thickness. Also, the molecular weight and saturation point of liquids are influential parameters after the enthalpy of evaporation. The surface temperature rises to a maximum value before reducing by the film evaporation. The maximum amount of the wall temperature depends on the liquid thermal
conductivity and the evaporation rate. Finally, the effect of the initial value of the film temperature is investigated, and a correlation for estimating the total evaporation time is extracted.
Three-Dimensional Printing as a Progressive Innovative Tool for Customized and Precise Drug Delivery
Authors: Aggarwal Kirti , Nagpal Kalpana
Published: August 2023

While using three-dimensional printing, materials are deposited layer by layer in accordance with the digital model created by computer-aided design software. Numerous research teams have shown interest in this technology throughout the last few decades to produce various dosage forms in the pharmaceutical industry. The number of publications has increased since the first printed medicine was approved in 2015 by Food and Drug Administration. Considering this, the idea of creating complex, custom-made structures that are loaded with pharmaceuticals for tissue engineering and dose optimization is particularly intriguing. New approaches and techniques for creating unique medication delivery systems are made possible by the development of additive manufacturing keeping in mind the comparative advantages it has over conventional methods of manufacturing medicaments. This review focuses on three-dimensional printed formulations grouped in orally disintegrated tablets, buccal films, implants, suppositories, and microneedles. The various types of techniques that are involved in it are summarized. Additionally, challenges and applications related to three-dimensional printing of pharmaceuticals are also being discussed.
Impact of Teaching Environmental Science (ES) On the Knowledge and Attitude Of Bhutanese Higher Secondary Students Towards the Environment
Authors: Tshewang Kinzang
Published: August 2023

Providing individuals with environmental awareness from a young age is important for a liveable and sustainable world. The aim of this study was to investigate the effect of teaching Environmental Science (ES) to classes IX-XII students. A convergent mixed method design guided by the pragmatism worldview was adopted for the study. Quantitative data were gathered from 130 participants and qualitative data from 5 students and 5 teachers from a higher secondary school. A descriptive and inferential statistics were used for quantitative data and the qualitative data were analysed through identification of themes. The results showed that students had a high degree of understanding and a positive attitude in environmental science and environment. Additionally, it was noted that there is little to no correlation between their knowledge and attitude about the environment. Thus, it was determined that students, particularly those in high schools, are being encouraged to develop their environmental literacy in order to promote the study of Environmental Science. Therefore, more efforts need be made to encourage ES at all levels of the schools to ensure effective implementation of the curriculum in the nation's sustainable development goals.
Benthic Macro-invertebrate Community Diversity of Orhuwhorun River in Udu Wetlands.
Authors: OSUINDE Gloria  Akohame , OLOMUKORO John Ovie
Published: August 2023

Benthic macro-invertebrate studies were done on Orhuwhorun River in Udu wetlands in Delta State, Southern Nigeria from March to December, 2011 in three selected stations. Sampling was done using a hand modified Eckman grab for sand and silt, the kick sampling technique and floatation method. They were sorted and identified using identification keys. A total of 2466 individuals were recorded in 66 taxa species belonging to thirteen (13) groups. Crustacean was the dominant group (36.29%) closely followed by gastropoda (35.60%) and diptera (21.04%). Significant similarity in fauna composition was observed. Station 3 had the highest population density with a relative abundance of 58.19% followed by station 2 (32.03%) and station 1 (9.77%). Diptera had the highest species diversity while nematode and lepidoptera had the least amongst the groups. Station 1 had the highest species richness (d) followed by station 3 and least in station 2. Species diversity showed no significant difference between the stations. Values for pollution tolerance index ranged between 13 and 15 at the stations. The highest value for pollution tolerance (PTI) was recorded in station 2 and the least in station 1. Positive significant correlations existed between most benthic organisms. The water quality is described as “fair”.
Effects of Cyanide on Some Histological and Immunohistochemical Parameters of Common Carp (Cyprinus carpio)
Authors: KAVASOGLU Mustafa , UYSAL Kazım , DEĞER Ayşenur
Published: August 2023

In this study, Bcl 2 and Caspase 3 expressions and histomorphological changes were investigated in the liver, gill and skin tissues of carp (Cyprinus carpio) in which 0,1 mg/L and 0,2 mg/L concentrations of cyanide were added to their environment. It was determined that the lipid accumulation, lymphocyte infiltration, fibrosis and regeneration in the liver tissues; hyperplasia, cell aggregates and goblet cells in the skin epithelium and gill filaments of fish exposed to cyanide. As a result of the study, it was observed that Bcl-2 expressions decreased and caspase-3 expressions increased in all tissues of fish exposed to cyanide at concentrations of 0,1 mg/L and 0,2 mg/L. Changes in Bcl-2 and caspase-3 expression levels result in disruption of the apoptosis mechanism in the liver, gill and skin tissues. At the end of the study, it was concluded that the examined parameters were a good indicator for cyanide intoxication.