bluuebunny/crossref_metadata_2025 huggingface dataset:
Formulasi Sediaan Krim Anti-aging dari Ekstrak Kolagen Limbah Sisik Ikan Bandeng (Chanos chanos)
Authors: Wahid Hilmiati , Karim Suhra Febrina , Sari Nurhikma
Published: September 2022

Penuaan dini merupakan kerusakan yang terjadi pada kulit akibat radikal bebas yang terbentuk melalui proses metabolisme dan dampak negatif lingkungan. Sisik ikan bandeng dipercaya mengandung kolagen yang dapat menghambat proses penuaan dini pada kulit. Penelitian ini bertujuan untuk mengetahui apakah formulasi krim anti-aging dari kolagen limbah sisik ikan bandeng (Chanos chanos) dapat memenuhi syarat mutu stabilitas sediaan dan untuk mengetahui konsentrasi efektif pada krim anti-aging. Sisik ikan bandeng diekstraksi dengan metode maserasi dan dikeringkan kemudian diformulasikan dalam bentuk sediaan krim dengan konsentrasi 5%, 6% dan 7% dan dilanjutkan dengan evaluasi sediaan meliputi uji organoleptik, homogenitas, pH, daya sebar, viskositas, uji iritasi dan uji aktivitas yang dilakukan kepada 16 orang sukarelawan dengan pengujian pada kulit punggung tangan selama empat minggu. Hasil penelitian krim anti-aging dari hasil uji stabilitas krim anti-aging ekstrak kolagen sisik ikan bandeng (Chanos chanos) dengan konsentrasi 5%, 6% dan 7% sudah memenuhi syarat mutu stabilitas sediaan krim dan dari hasil uji  aktivitas kadar air (moist) dan kadar minyak sediaan krim anti-aging dengan konsentrasi 5%, 6% dan 7% sudah memberikan efek anti-aging dalam memperbaiki kondisi kulit dengan nilai signifikansi pada tiap konsentrasi diperoleh nilai (P>0,05) menunjukkan tidak ada perbedaan bermakna pada tiap konsentrasi. Dapat di simpulkan bahwa krim anti-aging konsentrasi 5% sudah memberikan efek anti-aging dalam memperbaiki kondisi kulit punggung tangan.
Faktor-Faktor yang Berpengaruh terhadap Kejadian Infeksi Saluran Pernafasan Akut (ISPA) pada Balita di Puskesmas Karubaga Kabupaten Tolikara
Authors: Togodly Arius
Published: September 2022

Infeksi Saluran Pernafasan Akut (ISPA) masih menjadi masalah kesehatan masyarakat yang utama. Hal ini karena angka kematian yang signifikan terkait dengan Infeksi Saluran Pernafasan Akut, terutama pada bayi dan balita. Diharapkan setiap anak akan mengalami 3-6 episode Infeksi Saluran Pernafasan Akut. Infeksi Saluran Pernafasan Akut menyumbang 40-60% dari semua kunjungan ke Puskesmas setiap tahun. Proporsi kematian akibat ISPA mendekati 20-30% pneumonia pada semua kematian balita. Menurut data Dinas Kesehatan Provinsi Papua, lima kabupaten dengan tingkat Infeksi Saluran Pernafasan Akut (ISPA) tertinggi adalah Kabupaten Lanny Jaya (88,9%), Kabupaten Tolikara (69,5%), Kabupaten Jayapura (17,9%), Kabupaten Merauke ( 17,6%), dan Kabupaten Mappi (13,3%). Melihat tingginya prevalensi Infeksi Saluran Pernafasan Akut (ISPA) di Kabupaten Tolikara yang menempati urutan kedua sebesar 69,5 persen, setelah Kabupaten Lanny Jaya yang menempati urutan pertama sebesar 88,9 persen. Tujuan penelitian ini adalah menganalisis faktor-faktor yang berhubungan dengan kejadian infeksi saluran pernapasan akut (ISPA) di Puskesmas Karubaga Kabupaten Tolikara. Penelitian ini dilaksanakan di Wilayah Kerja Puskesmas Karubaga Kabupaten Tolikara pada bulan Juni – Agustus 2021. Populasi dalam penelitian ini adalah seluruh balita yang berkunjung ke Puskesmas Karubaga Kabupaten Tolikara pada tahun 2021. Sampel sebanyak 66 balita dipilih secara purposive sampling . Analisis data menggunakan statistik chi-square dengan taraf signifikansi 5%. Hasil penelitian menemukan bahwa kelima faktor yang diteliti adalah status imunisasi (p-value = 0,608 > 0,05), riwayat pemberian ASI eksklusif (p-value = 0,059 > 0,05), status gizi balita (p-value = 0,271 > 0,05), kebiasaan merokok pada keluarga balita (p-value = 0,775 > 0,05), dan penggunaan obat nyamuk bakar (p-value = 1.000 > 0,05) semuanya tidak berhubungan bermakna dengan Penyakit Infeksi Saluran Pernafasan Akut (ISPA) di Puskesmas Karubaga Kabupaten Tolikara.
Uji Daya Hambat Ekstrak Etanol Daun Gedi Hijau (Abelmoschus manihot L.) Terhadap Pertumbuhan Streptococcus mutans
Authors: Paerah Indah Pratiwi Astuti , Hashary A. Rufaidah , Asri Nur
Published: September 2022

Tumbuhan Gedi Hijau (Abelmoschus manihot L.) mengandung saponin, kuinon, tanin, dan flavonoid yang memiliki sifat antibakteri. Menggunakan antibiotik yang tidak tepat memungkinkan terjadi resistensi. Penelitian ini bersifat eksperimental dengan tujuan mengetahui aktivitas ekstrak etanol Daun Gedi Hijau (Abelmoschus manihot L.) terhadap Streptococcus mutans yang merupakan bakteri penyebab kerusakan gigi. Metode pengujian dilakukan dengan metode difusi paper disc. Sampel yang digunakan adalah Ekstrak Etanol Daun Gedi Hijau (Abelmoschus manihot L.) dengan konsentrasi 2%, 4%, dan 8% serta kontrol positif Amoksisilin dan kontrol negatif Aquadest. Hasil penelitian ini menunjukkan Ekstrak Etanol Daun Gedi Hijau (Abelmoschus manihot L.) memiliki aktivitas menghambat pertumbuhan Streptococcus mutans.
Hubungan antara Tingkat Pengetahuan dengan Kesediaan Vaksinasi Covid-19 pada Masyarakat di Kabupaten Kutai Kartanegara
Authors: Apriani Welin Devsi , Dewi Sinta Ratna
Published: September 2022

Virus SARS coronavirus-2 dapat menyebabkan penyakit infeksi COVID-19. Ketika jumlah kasus COVID-19 melonjak, penularan virus corona harus dikendalikan dengan mengikuti berbagai program pemerintah salah satunya vaksin. Adanya pengembangan vaksin COVID-19 ini menimbulkan banyak permasalahan penolakan vaksinasi dikarenakan banyaknya isu hoax mengenai vaksin. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat pengetahuan dengan kesediaan vaksinasi COVID-19 di Kabupaten Kutai Kartanegara karena kurangnya pengetahuan dapat mempengaruhi berbagai prilaku masyarakat. Jenis penelitian ini adalah kuantitatif dengan metode cross sectional. Pengambilan sampel menggunakan data kuesioner yang berisi 20 pertanyaan, 10 pertanyaan variabel pengetahuan dan 10 pertanyaan variabel kesediaan yang di sebar secara offline di 4 puskesmas Kecamatan di Kabupaten Kutai Kartanegara dengan cara random sampling. Sampel yang digunakan pada penelitian ini sebanyak 117 responden yang kemudian dicari hubungan kedua variabel dengan korelasi spearman’s rho. Hasil penelitian menunjukkan mayoritas responden mengetahui mengenai vaksinasi COVID-19 (90%) dan tidak mengetahui (10%) sedangkan responden menyatakan bersedia di vaksinasi (92%) dan tidak bersedia (8%). Dari hasil uji korelasi spearman’s rho penelitian ini didapatkan nilai signifikan 0,000 <0,05 dengan nilai koefisien korelasi 0,436. Kesimpulannya terdapat hubungan antara tingkat pengetahuan dengan kesediaan vaksinasi COVID-19 pada masyarakat di Kabupaten Kutai Kartanegara, oleh karena itu semakin tinggi ilmu pengetahuan semakin besar pula ketersediaan untuk di vaksinasi.
Determinación de la dosis óptima de policloruro de aluminio en una PTAP del Pacifico colombiano
Authors: Correa-Turizo Rafael , Mestre-Martínez Ruby , Baldiris-Navarro Ildefonso , Sánchez-Aponte Jorge , Martínez-Pájaro Cesar
Published: September 2022

Se determinó la dosis óptima de policlorurode aluminio aemplear en la planta de tratamiento de Aguas del Atrato. La recolección de muestras fue de manera compuestas, tomadas directamente del pozo de entrada del agua en la plata Loma de Cabi, mediante testde jarra a diferentes revoluciones por minutos, adición de PACa diferentes concentraciones, cantidades y el diseñó un formulario para la recolección de los datos, se determinaron las dosis óptimas y condiciones necesarias para la floculación y coagulación de las aguas tratadas en la planta. La concentración óptima para el tratamiento del agua cruda es de PAC al 1.5%V/V, con variación en la dosificación por los constantes cambios en la turbidez del recurso hídrico debido a la frecuente variabilidad del clima en la zona.
L'utilisation de la pleine conscience pour la santé mentale: apport des neurosciences et développements récents
Authors: MARTIN SOELCH Chantal
Published: September 2022

pas de résumé pour l'éditorial
Learning and memory : neurosciences perspectives
Authors: Poiintet Julia , Fahim Fahmy Cherine
Published: September 2022

Learning is the process of acquiring new or modifyingexisting knowledge, skills, behaviors or preferences (Schachter et al., 2010)

 

Memory is the faculty of encoding, storing and retreiving information (Squire, 2009)

 

Basic forms of learning were demonstrated at earlier and earlier stages of development, including in utero (Blumberg et al., 2010, Kail and Spear, 1984)

 

There are multiple brain learning/memory systems, age-specific ecological adaptions, and acquisition-vs.-expression of learning  (Krasnegor et al., 1986, Shair et al., 1991, Spear and Campbell, 1979). 

 

Rats show “infantile amnesia” (Campbell and Campbell, 1962, Campbell and Spear, 1972). The discovery that rodents show poor long-term memory for experiences occurring in infancy suggested that the human phenomenon has a biological basis. 

 

The neurobiology of learning and memory during adolescence showed specific sex/gender effects (Spear, 2009, Raznahan 2019).

 

There is a strong relationship between neurobiological and behavioral changes specifically during the adolescent period: alterations in fronto-striatal systems during adolescence impact risky decision making and vulnerability to social pressures, which may ultimately provide a framework for the development of reward-related learning abilities (DePasque & Galvan 2017).

 

Involvement of NMDA glutamate receptors in impairments in fearextinction during adolescence, and how the role of NMDA receptorsmay differ during this stage of development compared to adults and juveniles (Baker and Richardson 2017). 

 

The maturation of cortical noradrenergic systems contributes to executive function (Mokler and colleagues 2017).
Unlocking record capacity and rate capability of HxCrS2 by proton-exchange pretreatment
Authors: Stiles Joseph , Soltys Anna , Song Xiaoyu , Lapidus Saul , Arnold Craig , Schoop Leslie
Published: September 2022

Unsustainable mining and limited availability of lithium-ion battery materials have created a driving need to develop alternatives such as sodium hosts.[1–4] The development of suitable anode materials remains a major challenge facing sodium-ion battery development. Efforts into studying the charge storage of sodium in transition metal sulfides have gained traction due to improved kinetics compared with oxides.[5] Van der Waals CrS2 has been predicted to be a good intercalation host for Na but has not been isolated as a bulk phase. Rather, [CrS2 ]− layers exist in delafossite-related materials such as NaCrS2 , which has only a moderate reversible capacity of about 100 mAh/g.[6] Here we present a new material, “HxCrS2” (denotes approximate composition) formed by proton-exchange of NaCrS2 which has a measured capacity of 728 mAh/g with significant improvements to capacity retention, sustaining over 700 mAh/g during cycling experiments. This is the highest reported capacity for a sulfide electrode and is higher than the capacity of antimony (576 mAh/g) which has been the most promising anode to date, pairing high capacity with high rates.[7] Pretreatment by proton-exchange offers a route to materials such as HxCrS2 which provide fast diffusion and high capacities for sodium-ion batteries.
A modular click ligand-directed approach to label endogenous aminergic GPCRs in live cells
Authors: Gómez-Santacana Xavier , Boutonnet Marin , Martínez-Juvés Carles , Catena Juan Lorenzo , Moutin Enora , Roux Thomas , Trinquet Eric , Lamarque Laurent , Perroy Julie , Prézeau Laurent , Zwier Jurriaan M. , Pin Jean-Philippe , Llebaria Amadeu
Published: September 2022

New technologies based on luminescence have been essential to monitor the organization, signaling, trafficking or ligand binding of G Protein-Coupled Receptors (GPCRs), but they rely on the overexpression of genetically modified receptors. As more and more studies indicate the importance of studying native receptors in their natural environment, it is essential to develop approaches allowing the specific labeling of native receptors. Here we report an innovative ligand directed approach to specifically label residues of native GPCRs upon ligand binding. To this end, we developed a ligand-directed toolbox based on a novel approach that uses molecular modules to build fluorescent ligand-directed probes that can label an archetypical aminergic GPCR (D1R). Our probes can be readily prepared before the labeling reaction from two molecular modules: an activated electrophilic linker which includes a fluorescent dye and a GPCR ligand that may include nucleophilic groups. Thanks to a fast and specific click reaction, the nucleophilic ligand can barely react with the activated linker before it is bound to the native target GPCR and the labeling reaction occurs. Subsequently, the ligand unbinds the GPCR pocket, leaving the receptor fluorescently labeled and fully functional. This novel labeling approach allowed us to label both D1 receptor in transfected cells and native receptors in neuronal cell lines. This approach will pave the way to develop new reagents and assays to monitor endogenous GPCRs distribution, trafficking, activity or binding properties in their native environment.
Level Structure of 58Cu Within Modified Surface Delta-Interaction
Authors: Hameed Dalal N. , Hasan Ali K.
Published: September 2022

The nuclear shell model with modified surface delta interaction MSDI was used to calculate the values of energy levels of the copper nucleus 58Cu. The neutron and proton in the model space 1p3/2 0f5/2 1p1/2 of the copper nucleus occur outside the closed core 56Ni. This research investigates the excitation energy and angular momentum. As a consequence, theoretical approaches are used to uncover a collection between excitation energies and classical coupling angles θa,b at various orbitals. Finally, we demonstrate that our results are supported by experimental evidence: Excitation energies have two major functions, both of which are influenced by classical coupling angles but are unaffected by angular momentum I.
RESOLUÇÃO DE PROBLEMAS EM FÍSICA POR MEIO DE ESTRATÉGIAS METACOGNITIVAS: PERCEPÇÕES DE UMA PROFESSORA
Authors: Biazus Marivane de Oliveira , Rosa Cleci Teresinha Werner da , Darroz Luiz Marcelo
Published: September 2022

O presente estudo propõe o uso de estratégias metacognitivas como possibilidade para resolução de problemas em Física, tomando como referência estudos desenvolvidos na área de modo a proceder ajustes e adaptações pertinentes. Nesse contexto, surge a problemática vinculada a operacionalização dessas estratégias em sala de aula, particularmente relacionada ao professor, que necessita se organizar para implementar um novo modelo didático. O problema de investigação é dado pela seguinte pergunta: Como os professores percebem a implementação de práticas pedagógicas distintas da que habitualmente utilizam? Em outras palavras, o estudo busca compreender os limites e possibilidades da inserção de estratégias metacognitivas para resolução de problemas em Física, a partir de aspectos inerentes ao professor. Para tanto, tomamos como sujeito do estudo uma professora de Física que foi preparada para utilizar estratégias metacognitivas na resolução de problemas em Física e analisamos seus registros em um diário de aula. Como resultados, o estudo identifica a importância de o professor reconhecer a sua capacidade de iniciativa e de desenvolvimento profissional, buscando alternativas para mudar as suas concepções e adotar novas perspectivas didáticas; ter consciência do seu papel como agente de transposição didática, procedendo às adaptações necessárias dos conhecimentos pedagógicos produzidos na academia conforme sua realidade e contexto; e estar ciente de que poderá encontrar resistência por parte dos alunos.
LITERATURA DE CORDEL E EDUCAÇÃO EM CIÊNCIAS: UMA ANÁLISE A PARTIR DE PERIÓDICOS E DO ENPEC
Authors: Francisco Junior Wilmo Ernesto , Araújo Paula Dayane Silva , Santos Edjames Alves , Yamashita Miyuki
Published: September 2022

Este estudo buscou compreender o papel e as possibilidades de interrelação entre o cordel e a educação em ciências a partir do mapeamento e caracterização de estudos publicados em periódicos nacionais e no Encontro Nacional de Pesquisa em Educação em Ciências entre 2010 e 2020. Os resultados apontam que os estudos são relativamente incipientes com tendência de crescimento nos últimos anos, sobretudo a partir de 2018. Há uma concentração na região Nordeste (13 dos 15 trabalhos), embora tenha se verificado uma dispersão institucional e a não consolidação de grupos de pesquisa/pesquisadores que tenham o cordel como foco de pesquisa. A análise qualitativa dos trabalhos permitiu elencar três principais funcionalidades do cordel: i) recurso de ensino (material de leitura); ii) objeto de análise (conceitual ou imagem da ciência) e; iii) recurso avaliativo (escrita de cordéis). Os resultados da análise qualitativa revelam, no geral, que ainda não há uma robustez teórico-metodológica na consecução dos trabalhos, bem como centralidade em aspectos conceituais. A dispersão da produção e o foco central em aspectos conceituais sugerem que a literatura de cordel tem elevado potencial para exploração, bem como a necessidade de novos estudos que aprofundem questões epistemológicas, permitindo assim novos olhares e perspectivas.
EL-İ‘CÂZÜ’L-BELÂGÎ EL-KİTÂBÜ’S-SÂNÎ:EL-BÂKILLÂNÎ-ABDÜLKÂHİR ES-SÜYÛTÎ-ER-RÂFİÎ
Authors: ARAZ İsmail
Published: September 2022

Bu çalışma, Muhammed Muhammed Ebû Mûsâ’nın el-İ‘câzü’l-belâgî el-kitâbü’s-sânî:el-Bâkıllânî-Abdülkâhir-es-Süyûtî-er-Râfiî adlı eserinin değerlendirmesinden oluşmaktadır. Kur’an’ın i‘câzını ele alan temel eserlerden dört tanesini mercek altına alan bu eser, alimlerin konuya yaklaşımını farklı bir okuma perspektifiyle kritik etmektedir. Eserlerde geçen açıklamalar, yazarın kendine özgü üslubuyla tetkik edilmekte; ilk bakışta muğlak ve girift görülen cümleler ayrıntılı bir şekilde çözümlenmektedir. Yazar kitap boyunca etkili düşünme, derin okuma ve metinlere nüfuz etme problemleri üzerinde durmaktadır. Kitabın temel iddiasına göre retorik anlamda sağlanan üstünlük, ancak aynı dilde yazılmış iki söz arasındaki seçkinliği saptayan derin okumayla idrak edilebilir. Kitabın birçok yerinde bu okumanın gerekliliğine atıf yapılmakta; ayet, hadis ve şiir örnekleri üzerinden teorik ve pratik boyutuna değinilmektedir. Çalışmamızda yazarın söz konusu metinlere yaklaşımı ele alınmış ve yazara göre metinlerin tahlil edilmesinde hangi unsurların zaruri olduğu değerlendirilmiştir. Yazarın i‘câz meselesini irdeleyen kitapları nasıl okuduğuna da ayrıca yer verilmiştir. Sonuç bölümünde ise kitabın misyon ve vizyonuna atıf yapılarak literatüre katkıları ele alınmıştır.
“PASSIO PERPETUAE ET FELICITATIS” AS A HISTORICAL SOURCE ON THE HISTORY OF EARLY CHRISTIANITY
Authors:   Russian State University for the Humanities, Lebedev Pavel N.
Published: September 2022

“The Passion of Saints Perpetua and Felicity” is in many ways a unique source on the history of early Christianity and the Roman Empire. Its uniqueness is evident not only in the structure of the text or its content but also in the complexity of issues related to its main characteristics as a historical source. The issues of dating, the interrelation of different versions of the text, original language, authorship and many others for a long time remain a matter of debate in foreign historiography. But in Russian historiography that martyrdom is still on the periphery of attention, and its scientific potential remains not fully disclosed. The paper provides an overview of the existing discussions about the nature of that early Christian text and solutions to the source issues associated with its study. The author proves that the “The Passion of Saints Perpetua and Felicity” has a quadripartite structure: authentic records of the martyrs Perpetua and Saturus, who died together with their comrades in Carthage at the beginning of the 3rd century, the eyewitness testimony of their execution, as well as a prologue and epilogue written by the unknown compiler. The paper also considers the perspectives for studying the text in the context of the relationship between the Christianity and the Roman Empire, in the course of the evolution of Christian thought, and through the prism of gender studies.
REGIONAL ASPECTS OF THE DEVELOPMENT OF THE CENTRAL ASIAN REGION
Authors:   Russian-Tajik (Slavic) University, Negmatova Shakhnoza R.
Published: September 2022

The article considers the regional aspects of the present development of the Central Asian region. The article analyzes why and how the attitude of the world’s leading centers towards Central Asia has changed, what significance the region is acquiring today in international politics. The article studies tendencies in multidirectional aspirations of external players, elements of possible cooperation and rivalry between them. In addition, the article touches upon the internal conflict potential of countries and its influence on the formation of a new regional political environment. The article also considers some security issues, in particular, the impact of the current situation in Afghanistan in connection with the seizure of power by the Taliban, on the already difficult regional political environment of Central Asia. Understanding the specifics of the regional political environment of Central Asia is necessary, first of all, for the states of the region themselves, to take constructive actions to maintain the stability of the region, by creating mechanisms for coordinating collective decisions, deepening mutual cooperation in practical terms, finding compromise solutions to resolve existing disputes and disagreements in order to ensure a more effective implementation of their national interests.
STATE POLICY FOR THE DEVELOPMENT OF THE MARITIME SILK ROAD. OPPORTUNITIES FOR RUSSIA (EXAMPLE OF THE NORTHERN SEA ROUTE)
Authors:   University of Mumbai, Bhagwat Jawahar V. ,   Lomonosov Nothern (Arctic) Federal University
Published: September 2022

The development of the Maritime Silk Road (MSR) of the 21st century is important in order to use the positive aspects of that policy in Russia for the development of the Northern Sea Route (NSR). The global nature of the Chinese Maritime Silk Road initiative and, in general, “One Belt, One Road” is emphasized by the growing participation of interested countries in their development. The positive aspects of the MSR development policy are important for the development of the NSR. As part of the study in the specifics of the MSR, development policy a number of works by international and Russian authors, as well as official data on the development and implementation of the Chinese transport policy, were analyzed. At the same time, tools of discursive and political analysis, methods of abstracting, data collection, systematization of research positions, strategies, official data, as well as the use of an institutional approach were used. Analyzing the features of the China transport policy showed some possibilities of their application in Russia for the development of the NSR. The paper summarizes recommendations on the development of the transport policy of the Russian Federation in relation to the NSR: the need to develop a set of measures to enhance international interest; the importance of conducting a comparative analysis with the Chinese policy of promoting the MSR.
ON THE RELATIONSHIP OF GEOELECTROCHEMICAL ANOMALIES WITH JOINTING (VOL’NOVSKOYE OIL FIELD, RYAZAN-SARATOV TROUGH)
Authors: Shigaev Vitaly , Sheshnev Aleksandr , Ivanov Aleksey
Published: September 2022

The issues of oil and gas deposits being confined to zones of jointing are considered in the paper. Based on the results of our field observations, the stages of formation and external manifestation of fracture zones in the geological environment were traced. Using the example of the Vol’novskoye oil field (the Saratov part of the Ryazan-Saratov trough), the tectonic confinement of the centrifugal erosion network to the anticlinal uplift under study has been established. The distribution of the total-rock content of Zn, Si, Cr, and Ni before and after the electrical treatment of the samples of the subsurface layer was compared on the studied area. A mosaic distribution of the whole concentration of these metals according to the initial data and a ring-shaped anomaly of increased values of the geoelectrochemical coefficient of activation of geochemical processes by direct electric current have been established. The interrelation of the distribution of abnormally high values of the coefficient of activation of geochemical processes by direct electric current with a probable nature of the propagation of stress-strain zones on the Vol’nov anticline was determined
SUBSTANTIATION OF THE LATE CRETACEOUS AGE OF THE ANDRIANOVKA SUITE (SREDINNY RIDGE, KAMCHATKA)
Authors: Soloviev Aleksey , Palechek Tatyana
Published: September 2022

The Andrianovka Formation exposed in the Sredinny Ridge (Kamchatka) is represented by green shales, quartzites, and amphibolites. Conclusions about the age of the deposits of the Andrianovka Formation were made on the basis of data on the ages of the underlying and/or overlying strata, and correlations with other structural units. For the first time, radiolarians of the Santonian-Early Campanian age were extracted from the least metamorphosed siliceous rocks of the Andrianovka Formation. The rocks of the Andrianovka Formation can be considered as a metamorphic analogue of the deposits of the Iruney Formation, which Santonian-Early Campanian radiolarians were also isolated from.
EXPOSITION IN THE PEAT MUSEUM OF TOMSK STATE PEDAGOGICAL UNIVERSITY DEDICATED TO PROFESSOR G.N. BLINKOV
Authors: Inisheva Lidia , Porokhina Ekaterina
Published: September 2022

The paper describes the exposition dedicated to the 125th anniversary of the birth of Professor G. N. Blinkov, which was opened in the Peat Museum of Tomsk State Pedagogical University in the spring of 2022. Professor G. N. Blinkov’s long-term work to study the peat resources of the Tomsk region and the materials about this period of his life collected in the Peat Museum are analyzed.
PCA REDUCTION IN NAPHTHENIC BASE OILS BY OPTIMIZING HDT CONDITIONS
Authors: Gómez Maria Elizabeth , Santos Liliana , Tapias Néstor , Vargas Clemencia , Lizcano Javier
Published: September 2022

Polycyclic Aromatics (PCA) are aromatic hydrocarbons and related sulphur and nitrogen compounds, containing three or more fused aromatic rings, which are considered as toxic compounds. PCA control is a complex task because the Base Oil production involves different processes with many variables such as pressure, temperature, feedstock quality, catalyst, etc. This study focuses on controlling the hydrotreating temperature as main variable in the reduction of PCA in Naphthenic Bases. Two Naphthenic distillate fractions taken from an industrial plant were hydrotreated in pilot plant at different temperatures. The results show that PCA are reduced as hydrotreating temperature increases; however there is an optimum temperature above it, the thermodynamic equilibrium of aromatic hydrogenation reverses, increasing as a result, the PCA content. These results were implemented in the industrial Unit by installing a hydrogen quench between the two industrial reactors to guarantee that the profile of temperature, due to exothermic character of some reactions, be always in the optimun operating range.
DEVELOPMENT OF AN ANALYTICAL MODEL FOR STEAMFLOOD IN STRATIFIED RESERVOIRS OF HEAVY OIL
Authors: Mercado Sierra Diana Patricia , Muñoz Navarro Samuel Fernando , Ordóñez Rodríguez Aníbal
Published: September 2022

The use of analytical models to predict reservoir behavior depends on the similarity between the mathematically modeled system and the reservoir. Currently, there are not any models available for the prediction of steamflood behavior in stratified reservoirs based on the characteristics of reservoirs found in the Colombian Middle Magdalena valley, because the existing analytical models describe homogenous or idealized reservoirs. Therefore, it is necessary to propose a new model that includes the presence of clay intercalation in zones submitted to steamflood. The new analytical model is founded on the principles describing heat flow in porous media presented in the models proposed by Marx and Langenheim (1959); Mandl and Volek (1967), and Closmann (1967). Then, a series of assumptions related to the producing and non-producing zones and steamflood were determined, thus defining the system to be modeled. Once the system is defined, the initial and boundary conditions were established to contribute to find specific solutions for the case described. A set of heat balancing procedures were proposed from which a series of integro-differential equations were found. These equations were solved by using the Laplace transform method. The mathematical expressions were defined for the calculation of parameters such as volume of the heated zone, the rate of instantaneous and cumulative heat losses, and the oil rate and recovery factor. We can find differences when comparing the model response with the simulation, because in the mathematical model, we cannot include phenomena such as drop pressure, relative permeability and the change of oil viscosity with temperature. However, the new analytical model describes approximately the steam zone behavior, when the heat flow in the clay intercalations is not in stationary state.
GEOMECHANICAL WELLBORE STABILITY MODELING OF EXPLORATORY WELLS – STUDY CASE AT MIDDLE MAGDALENA BASIN
Authors: Carvajal Jiménez Jenny Mabel , Valera Lara Luz Carime , Rueda Alexander , Saavedra Trujillo Néstor Fernando
Published: September 2022

This paper presents the geomechanical wellbore stability model of an exploratory well sited at Middle Magdalena Basin (MMB), which is based on the validity of linear elastic deformational theory for porous media; the use of correlations and field tools such as well and image logs to indirect determination of mechanical properties and stress state. Additionally, it is shown the model calibration and validation using drilling events which occurred at other previously drilled wells in the study area, at the exploratory well itself and experimentally evaluated mechanical properties on outcrop and core samples from the basin formations. This application allowed the Instituto Colombiano del Petróleo (ICP) at Ecopetrol S.A. to formally perform the geomechanical modeling of Colombian formations and to accomplish a complete and appropriate methodology to do so; such methodology has been standardized as part of the drilling support process at Ecopetrol S.A., supplying the possibility for taking decisions that contribute to reduce drilling costs and risks during operations.
Atypical presentation of Morgagni hernia: Bowel loops in the neck
Authors: Akkaya Hüseyin , Dilek Okan , Sert Mustafa , Parlatan Cenk , Gülek Bozkurt
Published: September 2022

Introduction

Morgagni hernia is a rare congenital anomaly caused by the fusion defect between the septum transversum and the sternum. Patients may be asymptomatic or present with respiratory symptoms, abdominal pain, retrosternal pain, abdominal fullness, or gastrointestinal obstruction. Chest X-ray and thoracic computed tomography (CT) are the most commonly used modalities in imaging.

Aim

We describe an adult case in which the transverse colon was herniated from the retrosternal area to the thyroid gland without a history of trauma or surgery.

Case study

A 24-year-old female patient living in the countryside presented to our hospital with the complaints of indigestion and chest pain persisting for 2 years. In the thorax CT examination of the patient, it was observed that the transverse colon had herniated to the retrosternal region and then to the neck.

Results and discussion

Most acquired anterior diaphragmatic hernias are due to blunt or penetrating traumatic injury. However, there are also case reports describing iatrogenic diaphragmatic hernias following a sternotomy performed during thoracic or cardiac surgery. In Morgagni hernia, the most frequently herniated organs are the greater omentum and transverse colon. There are also reports, albeit rarer, describing the herniation of the stomach, liver and small intestines.

Conclusions

Morgagni hernia is a very rare type of hernia, especially in adult patients. The diagnosis of these patients can be easily made based on thoracic CT findings.
Oscillation Control of Two-Wheeled Robot using a Gyrostabilizer
Authors: ÜNKER Faruk
Published: September 2022

Two-wheeled robots are popular in transportation applications because of their high maneuverability. In this research, the oscillation attenuation performance of the control moment gyroscope (CMG) for the two-wheeled robot was studied. The stored kinetic energy of a CMG can offer a weight and volume saving compared to conventional vibration absorbers. This CMG is also more reactionless than other conventional absorbers by transforming the impact of angular momentum to unidirectional thrust along the center of gravity. The gimbals can precess while providing the angular momentum under the gravitational force. This study indicated that the CMG can operate in a wide range of excitation frequencies to balance the robot in a stable period. Because the flywheel speed is much easier changed to thrust against the unwanted oscillations disturbing the robot stability. There is a relation between the gimbal amplitude and the flywheel speed of CMG, in which the required flywheel speed can be reduced if the higher gimbal amplitude is chosen. It can be also concluded from the study that the oscillation amplitudes at the target frequency can decrease as much as flywheel speed increases. There was also a mathematical model using ANSYS software. The simulation results using ANSYS matched well with the theoretical results of the Lagrangian model.
Kullanılamayan Zaman Dilimlerinin ve Sıra Bağımlı Hazırlık Sürelerinin Olduğu Paralel Makina Çizelgeleme Problemi
Authors: ÖZÇELİK Feriştah , SARAÇ Tuğba
Published: September 2022

Makine çizelgeleme problemlerinde tüm makineler daima kullanılabilir durumda değildirler. Planlı bakım, öğle yemeği ve dinlenme molaları gibi nedenlerle periyodik olarak kesintilere uğrayabilmektedirler. Ancak literatürde genellikle bu durum göz ardı edilmektedir. Bu çalışmada kullanılamayan zaman dilimlerinin ve sıra bağımlı hazırlık sürelerinin olduğu ilişkisiz paralel makine çizelgeleme problemi ele alınmıştır. Ele alınan problem için bir matematiksel model geliştirilmiştir. Önerilen matematiksel modelin performansı rassal türetilen test problemleri kullanılarak gösterilmiştir. Kullanılamayan zaman dilimlerinin dikkate alınmasıyla son için tamamlanma zamanlarında ortalama %5,29’luk bir azalma sağlanmıştır.
Impactor Diameter and Ply Number Effects on the Impact Behavior of Carbon Fiber Composite Laminates
Authors: ÖZSOY Mehmet İskender
Published: September 2022

As it is known, impact damage is a major mechanical phenomena for composite materials especially used in the aerospace structures. The factors affecting the impact behaviour of the composites depend on the impactor systems as well as the target material. In this study ply number and impactor geometry effects of carbon fiber reinforced epoxy composites were investigated by impact tests. In this context, drop weight impact tests were carried out at 6J, 12J and 24J energy levels by using hemispherical impactors with 10 mm and 20 mm diameters. Laminated composites were manufactured in 6, 10 and 14 plies with vacuum infusion method. The effects of laminate thickness, impactor diameter and impact energy effects on the force, velocity, absorbed energy and damage surfaces were investigated. It is observed that impactor geometries and velocities caused the different damage mechanisms in composites and impactors played an important role in determining the penetration and perforation behaviours of composites.
Improved Knowledge Distillationwith Dynamic Network Pruning
Authors: ŞENER Eren , AKBAŞ Emre
Published: September 2022

Deploying convolutional neural networks to mobile or embedded devices is often prohibited by limited memory and computational resources. This is particularly problematic for the most successful networks, which tend to be very large and require long inference times. Many alternative approaches have been developed for compressing neural networks based on pruning, regularization, quantization or distillation. In this paper, we propose the “Knowledge Distillation with Dynamic Pruning” (KDDP), which trains a dynamically pruned compact student network under the guidance of a large teacher network. In KDDP, we train the student network with supervision from the teacher network, while applying L1 regularization on the neuron activations in a fully-connected layer. Subsequently, we prune inactive neurons. Our method automatically determines the final size of the student model. We evaluate the compression rate and accuracy of the resulting networks on an image classification dataset, and compare them to results obtained by Knowledge Distillation (KD). Compared to KD, our method produces better accuracy and more compact models.
PENCEGAHAN TERJADINYA GANGGUAN MENTAL SERIUS PADA MASA PANDEMI COVID-19 MELALUI PENINGKATAN KEMAMPUAN SELF HELP PADA REMAJA
Authors: Cahyanti Ika Yuniar , Ambarini Tri Kurniati , Kusumastuti Dhian , Abdillah Anang Arief , Baswara Theodore
Published: September 2022

Pandemi COVID-19 berdampak terhadap berbagai aspek kehidupan manusia termasuk masalah kesehatan mental. Remaja menjadi kelompok yang juga merasakan dampak dari kondisi pandemic COVID-19 ini seperti perubahan lingkungan belajar yang memicu rasa malas kegagalan dalam belajar, kecanduan game online, hingga permasalahan pada interaksi sosial. Karakteristik remaja yang tertutup membuat permasalahan yang dihadapi oleh remaja kerap tidak diketahui oleh guru maupun orangtua. Maka dibutuhkan kemampuan self-help guna mencegah gangguan mental pada remaja. Penelitian ini bertujuan untuk membekali remaja dengan pengetahuan mengenai kemampuan self-help. Kemampuan self-help merupakan kemampuan menolong diri sendiri dalam keadaan tidak meyenangkan yang diharapkan dapat mencegah gangguan mental pada remaja. Pengetahuan yang diberikan pada kegiatan ini adalah pengetahuan gaya belajar, asertivitas, dan manajemen diri. Kegiatan dilakukan kepada para siswa MAN 2 Pontianak dengan metode webinar dan diskusi melalui whatsapp grup. Terdapat total 15 data pre-test dan post-test pada kegiatan ini. Terdapat perbedaan rata-rata skor pada seluruh variabel yang diukur pada kegiatan ini yaitu pengetahui tentang gaya belajar, pengetahuan tentang asertivitas, pengetahuan tentang manajemen diri, tingkat asertivitas dan tingkat manajemen diri. Analisis uji beda paired sample t-test menunjukkan bahwa nilai p < 0,05. Hal ini menunjukkan terdapat perbedaan signifikan antara pengetahuan gaya belajar serta tingkat keterampilan manajemen diri antara sesi pre-test dan post-test. Selain itu nilai p > 0,05 menunjukkan bahwa tidak terdapat perbedaan signifikan antara pengetahuan asertivitas, tingkat asertivitas dan pengetahuan mengenai manajemen diri sebelum dan setelah kegiatan intervensi diberikan. Terjadi kenaikan skor pengetahuan para remaja mengenai cara melakukan self-help. Maka dapat disimpulkan bahwa tujuan dari kegiatan ini berhasil tercapai.
Determination of erythrocyte Glutathione S-Transferase activity in individuals with gastric and colon cancer
Authors: GÖKCE Kemal  , DAG Seker  , ÖZPINAR Hülya
Published: September 2022

Glutathione-S-Transferase (GST) in human cells has great importance in the detoxification mechanism of carcinogenic chemicals. Therefore, (GST) may be a useful tumor marker. This study examines whether GST activity in Gastric cancer (GC) and Colon Cancer (CC) is a helpful marker in diagnosing and monitoring the disease course. GST activity was investigated in patients with CC and GC and healthy individuals. Erythrocyte isolation was performed in 3 ml blood samples from volunteers aged 18-75 years. Hemoglobin amounts were determined from the standard graph drawn by monitoring the conversion of methemoglobin to cyanmethemoglobin in the presence of cyanide at 540 nm. Glutathione S-transferase activity was determined by measuring the amount of enzyme that catalyzes 1 µmol of S-(2,4-dinitrophenyl) glutathione formed per minute using 1-Chloro-2,4-Dinitrobenzene. The mean values of GST activities of patients with CC and GC, respectively; (1.28 ± 0.23 U/gHb; 1.20 ± 0.30 U/gHb), were significantly higher when compared to the mean values of healthy individuals with GST activity (0.59 ± 0.13 U/gHb) (p < 0.05). The GST activity of patients with colon cancer, measured as (1.56 ± 0.13 U/gHb) after chemotherapy, was significantly higher than before (1.09 ± 0.12 U/gHb) (p < 0.05). GST activity measured as (1.53± 0.24 U/gHb) after chemotherapy in gastric cancer patients was significantly higher when compared to the value measured before chemotherapy (0.97± 0.12 U/gHb) (p < 0.05). Our results show that the change in GST activity in CC and GC can be used as a biomarker to monitor the disease course and response to chemotherapy.
Predikisi Rata-Rata Curah Hujan Bulanan di Pasuruan Menggunakan Metode Holt-Winters Exponential Smoothing
Authors: Aini Afifah Nur , Intan Putroue Keumala , Ulinnuha Nurissaidah
Published: September 2022

Curah hujan merupakan butiran – butiran air yang keluar dari gumpalan awan. Curah hujan sangat penting dalam berlangsung nya kehidupan sehari – hari. Penelitian ini bertujuan untuk meramalkan  rata – rata curah hujan bulanan di Pasuruan dengan menggunakan Metode Holt- Winters Exponential Smoothing. Dimana Metode Holt- Winters Exponential Smoothing merupakan salah satu metode yang dapat digunakan untuk melakukan perhitungan prediksi untuk kedepan nya dengan menggunakan data pada tahun sebelumnya dimana pola data yang digunakan merupakan pola data trend dan pola data musiman. Data yang digunakan untuk penelitian  ini adalah data rata – rata curah hujan bulanan di Pasuruan  pada tahun 2015 – 2019. Data yang didapat merupakan hasil dari Badan Pusat Statistik Pasuruan. Hasil dari penelitian yang dilakukan ini didapat nilai  α=0,024281 ,β=0 ,dan  γ=0,084768 dengan MAPE yang didapat adalah 41% dimana dapat dikatakan bahwa pada metode Holt – Winters Exponential Smoothing menggunakan Model Multiplicative cukup baik dalam melakukan prediksi rata – rata curah hujan di Pasuruan.
Kesesuaian Penggunaan obat Golongan Analgetik terhadap Formularium Nasional dan Formularium Rumah Sakit di RS Akademik UGM Yogyakarta
Authors: Azis Muhammad Israwan , Endarti Dwi , Satibi Satibi , Taufiqurohman Taufiqurohman
Published: September 2022

Peraturan Menteri Kesehatan Nomor 72 Tahun 2016 mengatur bahwa setiap tenaga farmasi rumah sakit yang memberikan pelayanan kefarmasian harus memenuhi standar pelayanan. Berdasarkan Standar Pelayanan Minimal Rumah Sakit, penulisan resep seluruhnya harus mengacu pada formularium dengan standar 100%. Jika resep tidak sesuai dengan formularium maka akan mempengaruhi mutu pelayanan obat serta mampu meningkatkan biaya penggunaan obat di instalasi farmasi. Penelitian ini bertujuan untuk mengetahui kesesuaian penggunaan obat golongan analgetik dengan formularium nasional dan formularium rumah sakit di Rumah Sakit Akademik UGM Yogyakarta. Jenis penelitian ini merupakan penelitian deskriptif dengan rancangan penelitian cross sectional dan pengumpulan data secara retrospektif. Data penggunaan obat golongan analgetik yang telah diperoleh dari sistem informasi manajemen rumah sakit pada periode tahun 2013, 2016, dan 2019 kemudian diolah dan dianalisis menggunakan microsoft excel. Hasil penelitian menunjukkan kesesuaian penggunaan obat golongan analgetik terhadap formularium rumah sakit untuk tahun 2013 dan 2016 sebesar 100%, sedangkan untuk tahun 2019 yakni sebesar 98,84% dengan rata-rata sebesar 99,6%.  Sementara untuk persentase kesesuain penggunaan obat terhadap formularium nasional untuk tahun 2016 dan 2019 yakni sebesar 64,57% dan 86,25% dengan rata-rata sebesar 74,41%.  kesesuaian penggunaan obat terhadap formularium nasional dan formularium rumah sakit belum memenuhi standar yang ditetapkan yakni 100%, sehingga rumah sakit masih perlu melakukan upaya untuk meningkatkan persentase kesesuaian penggunaan obat di Rumah Sakit Akademik UGM Yogyakarta.
The Effect of Black Cumin Seed Oil on Alanine Aminotransferase Levels which are Influenced by Nutritional Status in Active Smokers
Authors: Santoso Arif , Hidayati Titiek , Akrom Akrom , Nurani Laela Hayu
Published: September 2022

Black cumin seed oil (BCSO) has the main compound thymoquinone which is thought to have hepatoprotective activity through an antioxidant mechanism. Exposure to cigarette smoke can cause cellular oxidative stress which is the key to the inflammatory process of liver cells and an increase in the activity of the Alanine aminotransferase (ALT) enzyme. Vitamin C and folic acid are nutrients that affect ALT levels through antioxidant activity. The main objective of this study was to see the effect of BCSO administration on ALT levels which were influenced by the intake of vitamin C and folic acid in healthy respondents who were active smokers for 30 days. This study used a single-blind Randomized Controlled Trial (RCT) method, with a total of 39 test subjects divided into four groups. Group 1 received 3x1 placebo, group 2 received BCSO 3x1, group 3 received BCSO 3x2, group 4 received BCSO 3x3. Investigation based on the ANOVA test, it turned out that there was no significant difference in the mean ALT levels in both the placebo group and the treatment group with p value = 0.452. For the p value of the intake of vitamin C and folic acid were 0.359 and 0.669, respectively. Based on the results of the study showed that the administration of BCSO for 30 days had no significant effect on the average activity of ALT in healthy active smokers and there was no significant difference in the intake of vitamin C and folic acid.
Phenomenological Study of Hemodialysis Therapy Compliance in Chronic Renal Failure Patients at El Syifa Hospital (Fresenius Kidney Care) Kuningan West Java
Authors: Taufik Ganjar , Sari Ika Puspita , Astuti Ika Yuni
Published: September 2022

The problem of kidney failure patients in El Syifa Hospital (Fresenius Kidney Care) In Kuningan, West Java continues to increase year on year and in 2019 by 140. By 2020 it will increase to 155 sufferers. The data of patients undergoing hemodialysis therapy. The purpose of knowing the cause of the phenomenon of renal failure and along with factors that affect the non-compliance of kidney failure patients to perform hemodialysis therapy El Syifa Hospital (Fresenius Kidney Care) Kuningan West Java. The research design method used is descriptive with purpusive sampling. Research instruments in the form of interviews, data in Analysis by Colaizzi method, the results of the study data on the type of kemalin men 60% and women 40% Due to the habits of smoking, drinking fizzy drinks, and alcoholic beverages. The result data was obtained, irregular participants (70%), and the tertur (30%) irregularities include economic factors (44%), health (4%), support (10%), employment (4%). No symptoms (6%), personal agitation (2%), duration 5 hours, and with a duration of 2 x in 1 week.