bluuebunny/crossref_metadata_2025 huggingface dataset:
Polycystic ovary syndrome: approach to correction of metabolic disorders
Authors: Л. В. Калугіна  , Т. Ф. Татарчук
Published: September 2020

Objective: to study the reliability of working hypothesis about positive effect of plant adaptogens with hepatoprotective and anti-inflammatory activity in correction of metabolic complications of polycystic ovary syndrome (PCOS) and to study the possibility of including schisandrin into treatment, choice of which is due to its properties to improve tissue sensitivity to insulin, hepatoprotective, hypolipidemic, anti-inflammatory and antioxidant effects.Materials and methods. A comparative prospective study of 60 patients aged 18–38 years with PCOS (phenotype A) was carried out. Criteria for inclusion in the study were: a confirmed diagnosis with increased ovaries and oligo-/anovulation, increased level of ovarian androgens; body mass index (BMI) from 25 to 30.1 kg/m2. All women underwent a general clinical examination evaluating anthropometric parameters and BMI, the presence of clinical manifestations of hyperandrogenism (hirsutism and androgenic dermatopathy) on a Ferriman-Gallwey scale, ultrasound of the genital organs, assessment of progesterone and insulin resistance based on the NOMA index on the 22–24th day of the menstrual cycle. Рatients were divided into 2 equal groups depending on the therapy: women in the main group were prescribed schisandrin 1 tablet (250 mg) three times a day for 12 weeks, patients in the control group received recommendations on diet and physical load.Results. The resulting course of treatment with schisandrin showed restoration of regular menstrual cycles in 40% of patients (versus 16.6% at the beginning of the study) due to a 1.4-fold increase in progesterone level, improvement of skin condition, BMI normalization. A positive effect of treatment on the metabolic status was also noted: a significant decrease in HOMA indices was observed, and transaminases levels were normalized.Conclusions. For a comprehensive examination of patients with PCOS, especially those who are overweight and obese, it is necessary to include a HOMA index assessment, functional liver tests, ultrasound of the hepatobiliary system with elastography. Complex therapy regimen should include schisandrin for prevention of metabolic disorders in women with PCOS and overweight.
Prevention of postpartum infectious and inflammatory complications in women with injuries of the lower parts of genital tract
Authors: Л. Б. Маркін  , Г. Б. Семенина  , К. Л. Шатилович  , Г. Я. Кунинець  , О. В. Шахова
Published: September 2020

Objective of the study: evaluation of the effectiveness of antimicrobial antiseptic drug Femiclean for prevention of wound infection in postpartum women with injuries of the lower parts of genital tract.Materials and methods. A clinical and laboratory examination of 65 postpartum women was carried out. I observation group consisted of 33 women who underwent surgical treatment for perineal rupture of the II degree or episiotomy. Processing of external genitalia with disinfectant solutions (potassium permanganate, chlorhexidine) three times a day for the first 2–3 days, dry treatment of the perineum sutures with iodine solution for 5 days was performed to these patients. II observation group consisted of 32 women with a perineal rupture of II degree or episiotomy, who in addition to the above-indicated preventive and therapeutic measures were prescribed vaginal Femiclean tablets for 5 days.Effectiveness of these measures was determined by presence of the postpartum complications (infiltration and suppuration in vaginal and perineum sutures), results of vaginal discharge microscopy (before and after treatment) and cytological smears from perineum sutures region (on the 5th day of the postpartum period).Results. A more significant improvement of the vaginal bacteriological status following the treatment with Femiclean was in II group patients as compared with women in group I. The favorable course of tissue regeneration in all patients of group II, which was clinically confirmed by the absence of suppuration and dehiscence of perineal wound edges, proves the effectiveness of the dequalinium chloride drug for prevention of wound infection. One of the advantages of local drug administration is the lack of significant adverse effects on the lactobacilli pool, that is important for restoration of vaginal normocenosis in the puerperal period.Conclusion. Topical application of the antiseptic drug Femiclean provides a 3-fold reduction in infectious and inflammatory complications incidence at trauma of the lower parts of genital tract.
The role of relative hyperprolactinemia in the genesis of the оvarian follicular cysts development
Authors: Т. Ф Татарчук  , Н. В. Косей  , О. В. Занько  , О. Г. Околох
Published: September 2020

Follicular ovarian cysts (FOC) today occur in 25–30% in the structure of all tumors and tumor-like formations in gynecological practice and tend to increase. The study presents the results of using four different treatment regimens for FOC treatment in patients aged 18 to 42 years. Group I (n = 46) consisted of women with uncomplicated course of FOC who received complex hormonal therapy for 3 months. Group II (n = 49) patients who received monotherapy with a special extract of the Vitex Agnus Castus BNO 1095 (Cyclodynon®) for 6 months. Group III (n = 47) – patients who received a combination of hormone therapy (3 months) and BNO 1095 (6 months). Group IV (n = 35) – patients who did not receive drug therapy (expectant tactics + lifestyle modification).The highest efficacy in relation to the elimination of FOC and the stability of the result during the year was observed in patients of group III who received complex hormone therapy + BNO 1095 extract. Elimination of FOC in 100% of patients within 3 months with a result of more than 95% of patients during the year. Complex hormonal therapy without the use of BNO 1095 (group I) also showed a rather high efficiency with respect to the regression of FOC, but the result was not stable. During the year, relapses in the formation of FOC were observed in 37% of patients. Monotherapy BNO 1095 (group II) demonstrated the efficacy of resorption of the cyst for 6 months in 87% of cases, with the result being preserved for over a year in almost 80% of patients. Active observation (group IV) showed fairly low efficacy: after a year of observation FOC had more of 63% of patients.The average prolactin level in the study groups was higher than the reference values. During the observation period, prolactin levels in all groups except the control group decreased statistically. After 12 months of follow-up, in the group of women who received a combination of hormone therapy with Cyclodynon®, steady normalization of steroid hormones, estradiol and progesterone, was observed, which is explained by the restoration of the biphasic menstrual cycle in most women of this group.The study confirms the role of functional hyperprolactinemia in the development of FOC and the advisability of prescribing Cyclodynon® in their treatment regimen both in combination with hormone therapy and monotherapy (if there are have contraindications to hormone therapy or reproductive plans).
Effect of endometrial injection scratching in cycles of treatment by assisted reproductive technology methods
Authors: Suslikova L. V. , Kaminskyi V. V. , Chayka K. V. , Kaminskyi A. V. , Serbeniuk A. V. , Zhykharskyi R. V. , Bondaruk O. Y.
Published: September 2020

Objective: optimization of pregravid (pre-pregnancy) preparation in patients with tubal-peritoneal infertility factor and marked delay in endometrial development after unsuccessful assisted reproductive technology (ART) treatment by the use of endometrium injection scratching technology with autoplasma.Material and methods. Study included 40 cases of unsuccessful treatment attempts for tubal-peritoneal factor infertility with severe delay of endometrial development and 10 patients with tubal-peritoneal factor infertility with normal endometrium with one or more unsuccessful ART attempts on history and the existence of cryopreserved embryos of satisfactory quality from previous cycles of assisted reproductive technology. The average age was 39.5 ± 3.1 years. Patients were divided into groups: I – 21 patients who underwent endometrial injection scratching and hormonе replacement therapy (HRT) with a standard (4/6 mg) dose of estradiol; II – 19 patients who were prescribed HRT with a standard (4/6 mg) dose of estradiol; control – 10 patients with normal endometrium who underwent cryo-ET with standard (4/6 mg) dose of estradiol.Clinical results were evaluated and compared in terms of pregnancy rate per embryo transfer and pregnancy loss rate in the first trimester. The correspondence of the morphofunctional structure of the endometrium was evaluated by ultrasound, cytologically, Doppler measurements, histologically, immunohistochemically and via selective electron microscopy. Endometrium was 8.9 ± 1.1 mm during the period of progesterone prescription in the cryoembryo transfer cycle. All participants were transferred day 5 embryos. Results. In the cryo-ET program autoplasma injection scratching in patients with marked delay of endometrial development after the first seven days of monotherapy with a starting dose of estradiol was accompanied by a significant improvement in clinical outcomes in terms of pregnancy rate (25%) and definite decrease of early reproductive losses (25%).Conclusions. After pre-pregnancy preparation according to our method, it is quite sufficient to perform HRT with a standard dose of estradiol (4/6 mg/day) before starting progesterone irrespective of the endometrial development degree. Meanwhile, injection scratching is advisable to be prescribed in cases of marked delay in the endometrium development and it should be combined with physiotherapy methods.
Mastоpathy is a biomarker of hormonal distress. Literature review
Authors: Т. А. Ермоленко  , Т. Л. Прутиян
Published: September 2020

Mastopathy is an extensive heterogeneous group of the mammary glands pathologies, varying in its manifestations and in degree of breast cancer risk. The prevalence of mastopathy in female population is 60–80%, and this pathology has an age-related epidemiological features. On the background of gynecological diseases benign breast diseases occur in 76–97.8% of women. Frequency of mastopathy is reduced with the onset of menopause, while the risk of malignant transformation increases. Breast tissue has a high concentration of cytosolic tissue receptors to steroid compounds, so like other organs of women’s reproductive system it is susceptible to 15 hormones. Estrogen concentration in the breast connective tissue in 2–20 times higher than in blood plasma. Decisive role in the emergence of breast pathology belongs not to the absolute concentrations of hormones in blood plasma, but condition of sex steroids receptors in breast tissue. Mastodynia is a reflection of functional changes and response of breast tissue to hormonal imbalance. Proliferative mastopathy without atypia and with atypia significantly increase the risk of breast cancer. Progesterone deficiency is a key factor in the pathogenesis of dishormonal breast diseases.For timely prevention, early diagnosis of breast diseases and breast cancer, prognosis and treatment tactics, mammography, MRI and ultrasound of the gland are used, as well as various biological markers (tissue, cellular and molecular) determination, steroid hormone receptors, various growth factors and their receptors are evaluated.The timely appointment of transdermal gel Progestogel® eliminates mastodynia and other symptoms of mastopathy, and is pathogenetic treatment, which prevents the transition of functional disorders into morphological in mammary glands, reduces mammographic breast density, and thus reduces oncology risk.Thus, prevention, early diagnosis, timely pathogenetic treatment of dishormonal breast diseases reduces the risk of breast cancer.
Delayed neurological maturation is a cause for distress during fetal growth restriction
Authors: Lakhno I. V. , Malikova S. E.
Published: September 2020

Theory of fetal programming contributes to a better understanding of the relationship of many human diseases with antenatal period pathology. Regulatory impact of nervous system is of great importance. Fetal growth restriction (FGR) is a convenient model for investigation of the abnormalities of fetal neurodevelopment. Fetal heart rate variability is a well-known approach for fetal autonomic function detection.The aim of the study was to detect several patterns of autonomic nervous regulation in FGR complicated by fetal distress or without fetal distress.Materials and methods. Totally 64 patients at 26–28 weeks of gestation were enrolled. 23 patients had normal fetal growth and were included in the Group I (control). 20 pregnant women with FGR without fetal distress were observed in Group II. 21 patients with FGR and fetal distress were included in Group III. Fetal heart rate variability and conventional cardiotocographic patterns were obtained from the RR-interval time series registered from the maternal abdominal wall via non-invasive fetal electrocardiography.Results. Suppression of the total level of heart rate variability with sympathetic overactivity was found in FGR. The maximal growth of sympathovagal balance was found in GroupIII. Fetal deterioration was associated with an increased quantity of decelerations, reduced level of accelerations, and decreased of short term variations and low term variations. But a decelerative pattern before 26 weeks of gestation was normal. Therefore fetal autonomic malfunction could be a result of persistent neurological immaturity in FGR. The approach based on the monitoring of fetal autonomic maturity in the diagnosing of its well-being should be tested in further studies.Conclusion. Fetal heart rate variability variables and beat-to-beat variations parameters could be the sensitive markers of neurological maturation and good predictors for fetal deterioration.
Current state of reproductive potential of Ukrainian women
Authors: Ю. Г. Антипкін  , В. Ф. Лапшин  , Р. В. Марушко  , О. О. Дудіна  , Н. Ю. Бондаренко
Published: September 2020

Objective of the study: to assess the main indicators of the reproductive potential of women in Ukraine in dynamics over the period 2000-2018.Materials and methods. Analysis was performed using the data of the State Statistics Service of Ukraine and the State Institution “Center for Medical Statistics of the Ministry of Health of Ukraine” for the period 2000–2018. The methods of a systematic approach, structural-logical, epidemiological analysis were used.Results. Reproductive process dynamic in Ukraine in the XXI century had nonlinear character – increase in the general fertility rate from 7.7 per 1000 population in 2000 to 11.4 in 2012 and the total fertility rate from 1.11 to 1.6, respectively with further deterioration trend – 8.7 and 1.3 in 2018, respectively. Low rates of population reproduction in Ukraine in the XXI century were kept on the background of insufficient resources to ensure the reproduction of the country's population – decrease of the number of women of childbearing age from 12,582.7 thousand in 2000 to 9,998.6 thousand in 2018 with adverse changes in the age profile towards older age groups, high level incidence of reproductive system in women.In 2000–2018 years there is a high level with a negative trend in the prevalence of menstrual disorders (increase by 38.5%), cervical inflammatory diseases (increase by 82.5%), malignant neoplasms of uterine body (increase by 39,9%), mammary glands (increase by 11.99%), cervix (increase by 5.06%), high frequency, with a negative trend, in the incidence of diabetes in pregnant (increase by 662.5%), thyroid disease (increase by 17.3%), circulatory system diseases (increase by 34.4%), urogenital system (increase by 8.7%). In the same time it was achieved a reduction of reproductive losses due to forced abortions by 1.75 times, decrease of mortality during first year of life by 1.7 times and feto-infantile losses of 1.4 times. Conclusion. In recent decades, in Ukraine kept unfavorable demographic situation - decrease in population due to extremely high mortality with low birth rates and low life expectancy.
Turismo no estado do Rio de Janeiro: o hiato entre a mobilidade e o desenvolvimento
Authors: Edra Fátima Priscila Morela , Dantas José Carlos De Souza
Published: September 2020

O texto apresenta a relação entre a cidade do Rio de Janeiro e o turismo no estado de mesmo nome e no país ao longo do século XX: projetos imaginados e inviabilizados por ações políticas não previstas. Dando prosseguimento, mostra-se a possibilidade de reviravolta deste cenário na primeira década do século XXI com políticas mais efetivas no âmbito do turismo com base em planejamentos para o sistema de transportes focado, essencialmente, nas mobilidades horizontal e vertical entre o sistema aéreo e deste com o rodoviário, respectivamente, visando interiorização do turismo como proposta pelo Ministério do Turismo por meio da Regionalização. A pesquisa foi bibliográfica em artigos, livros e documentos públicos com acesso livre e estudos de campo realizados durante a inventariação da oferta turística do estado do Rio de Janeiro ao longo do ano de 2016. O objetivo principal foi identificar a distância turística existente no estado do Rio de Janeiro entre os subpolos do IOT RJ e fomentar a reflexão sobre a interface entre mobilidade e turismo. Os resultados mostraram a urgente necessidade de um gerenciamento da mobilidade que atue como indutor do turismo no Estado.Palavras chave: Turismo; Mobilidade; Rio de Janeiro; IOT-RJ.
EMPLOYERS PERCEPTION ON GRADUATE SKILL DEFICIENCY TO SUIT PRODUCTIVITY
Authors: Soundararajan Gopalakrishnan , Ravikumar Anitha , Aro-Gordon Stephen
Published: September 2020

Purpose of the study: This study aims to investigate the perception of employers on the skill deficiency of graduates. The study also attempts to explore the nature and importance of employability skills with emphasis on the areas of deficiency that could be addressed by higher education institutions (H.E.I.s) to make their graduates more employable.
Methodology: This paper is a theoretical exploration based on existing literature. Relevant research papers were sourced from prominent online databases, notably Emerald and Elsevier, including journals, articles, and scholarly conference proceedings. and carefully analyzed. These studies provided an insight for the researchers to understand employability skills and also it helped to suggest the steps to be taken by the H.E.I.s to address the lack of employability skills and make the students ready to face the job market.
Main Findings: The results of the study suggest that a lack of employability skills is a major cause of unemployment among graduates of universities, colleges, and other H.E.I.s.The findings reflect the increasing desire of employers for graduates to possess soft skills such as critical thinking, problem-solving and effective communication, and collaboration. It also underscores the critical role of H.E.I.s in addressing graduate skill deficiencies.
Applications of this study: The study shows that employability skills are the foremost skills graduates require to successfully compete in the job market. The research encourages graduates to understand the skills deficiencies from the employers' perspectives and to discover some bespoke methods or ways of addressing their competency gaps, thereby enhancing their effectiveness and innovativeness. The study further offers a clear roadmap for H.E.I.s to enrich the quality of teaching and learning, thereby enhancing graduate employability. Thus, the outcome of this study will help not only the students but also the H.E.I.s and employers.
Novelty/Originality of this study: The study extends the current literature on graduate employability by integrating the three pivotal dimensions of the problem – the students, the H.E.I.s, and the employers. Previous studies have focused more on some specific aspects such as employability skills needed or expectations of the employers or stressed on H.E.I.s to create employability skills. Students are dependent on H.E.I.s for their studies while they are also dependent on employers for getting jobs; similarly, the H.E.I.s cannot function without the students, while the employers also cannot function without the human resource provided by the H.E.I.s.
CLARIFICAÇÃO DO CALDO DE CANA-DE-AÇÚCAR UTILIZANDO A REAÇÃO DE PEROXIDAÇÃO COM INCIDÊNCIA DE LUZ ULTRAVIOLETA
Authors: DE OLIVEIRA SAMPAIO DANTAS ÁDILA , COIMBRA DA SILVA CAVALCANTE LORENA , EMANUELLA DE SOUZA DOS SANTOS GRAZIELLE , LÚCIA DE PAIVA E SILVA ZANTA CARMEM , HELENA VIEIRA DE CARVALHO SANDRA
Published: September 2020

Atualmente, para clarificação e fabricação do açúcar comercial, utiliza-se o processo de sulfitação, que tem gerado controvérsias com relação ao impacto na saúde dos consumidores. Métodos alternativos são estudados no intuído de substituir os compostos à base de enxofre. A reação do peróxido de hidrogênio sob a presença de luz ultravioleta é um dos processos oxidativos avançados promissores, e comprovadamente eficaz. O presente trabalho avaliou este processo para o caldo de cana-de-açúcar com o objetivo de produzir um açúcar de maior valor agregado, utilizando duas concentrações (0,5 e 1,0 mol/L) de H2O2 e considerando os efeitos da luz ultra-violeta. De acordo com os resultados, pôde-se obter uma clarificação de até 55%, quando se utiliza concentrações de 0,5 mol/L de peróxido de hidrogênio sob o efeito da luz UV, mostrando assim, que há viabilidade nesse método alternativo.
PCP: ANÁLISE NO SETOR DE USINAGEM DE UM FABRICANTE DE EQUIPAMENTOS MÉDICOS EM SÃO CARLOS INTERIOR DE SÃO PAULO
Authors: Avelina Bataghin Costa Marcela , Rodrigues Alison Lopes , Sulino Gustavo
Published: September 2020

O Planejamento e Controle da Produção (PCP) da empresa, responsável por programar e controlar a produção além de coordenar as atividades de vários departamentos como vendas, produção, compras, entre outros. O artigo identificou gargalos no PCP e no setor de usinagem de uma fresa cirúrgica BRD em uma empresa do setor de ortopedia na cidade de São Carlos, SP. - Brasil. Realizou-se uma revisão bibliográfica e documental, seguida de um estudo de caso. O estudo de caso foi conduzido por meio de uma entrevista semiestruturada a um gerente da empresa. Os dados levantados possibilitaram caracterizar a empresa e o processo de fabricação da fresa BRD. O resultado apontou que a comunicação entre o setor de PCP e de usinagem carece de melhor estruturação. Observou-se que PCP da empresa não possui um desempenho satisfatório no que se refere a programar e controlar a produção
Investigating the Process of Producing Composite Hydrogel Particle Slurry
Authors: Makarenkov D.A. , Fedorova E.M. , Buchryakova V.A. , Lobastov S.L. , Nazarov V.I. , Boldyrev V.S.
Published: September 2020

The paper presents comprehensive investigation results concerning obtaining a composite hydrogel material in the form of an aqueous slurry. We considered the issue of grinding hydrogel in water so as to obtain an aqueous slurry of hydrogel particles featuring the desired particle size distribution. We selected polyacrylamide to be the composite hydrogel material and used an anti-Stokes phosphor as a filler. We describe a multi-stage method for producing hydrogel, a coarse grinding process for hydrogel blocks, and a fine grinding technology employing an immersion disperser. We obtained slurries featuring a narrow particle size distribution (160--1000 µm). We provide data on investigating how the manufacturing process parameters and modal parameters of the equipment used affect the particle size distribution in the resulting hydrogel material. We propose a technology for producing composite hydrogel particle slurry in a single process cycle
The Initial Surface Structure of Co3O4 as a Factor of Influence on Kinetic Features of the Dissolution of the Solid Phase
Authors: Eliseeva E.A. , Berezina S.L. , Gorichev I.G. , Slynko L.E. , Goryacheva V.N.
Published: September 2020

Due to the depletion of natural reserves of cobalt-containing ores, it is urgent to optimize the processes of cobalt replenishment, based on the leaching of its compounds, processing of industrial waste, regeneration of cobalt compounds from catalysts. The kinetic characteristics of the dissolution of metal oxides are influenced by the initial state of their surface structure, which requires the accumulation of experimental material and individual targeted studies. The paper presents the results of an experimental study of the surface structure of industrial Co3O4 cobalt oxide samples. The studies were carried out by electron microscopy and X-ray phase analysis and revealed the size and shape of the Co3O4 particles and the nature of their surface distribution. The correspondence of experimental and theoretical data has been established, Co3O4 cobalt oxide has been identified as an α-form of the cubic crystal system. The data obtained are of interest in the study of the effect of the surface characteristics of the solid phase of Co3O4 cobalt oxide on the dissolution kinetics under the chemical and electrochemical influence
Dimensions of the Political in Adjudication: A Case Study
Authors: Mańko Rafał
Published: September 2020

Contrary to traditional accounts, which treat adjudication as the application of legal norms to the facts of a case, without any creative activity, the present paper assumes, following crtitical legal theory, that adjudication as a social practice belongs to the sphere of the political and involves judicial decision-making. The concept of the political is understood, following Chantal Mouffe, as the dimension of unalienable and inherent antagonism underlying any society. Any judicial decision, and especially one taken in a case where the court enjoyed a broad scope of discretion, influences a given social antagonism. However, as a prerequisite of a critical analysis of case-law it is necessary to identify the social antagonisms in question. To this end, the paper first analyses the very concept of an antagonism, highlighting its collective character, and then makes a tentative application of the concept to the European Court of Justice, attempting to identify the main types of social antagonisms which are subject to the Court’s jurisdiction.
Konflikt norm pomiędzy maoryskim zwyczajem pochówku a nowozelandzkim prawem ustawowym
Authors: Siekiera Joanna
Published: September 2020

Celem artykułu jest przedstawienie konfliktu norm w porządku prawnym Nowej Zelandii na podstawie zwyczajowego pochówku Maorysów (tangihanga). Konflikt pozostaje nierozwiązany, a dotyczy wielu obywateli. Prawo nowozelandzkie to hybryda zwyczajowych i religijnych norm pochodzących od rdzennej mniejszości maoryskiej i brytyjskiego systemu prawa precedensowego. Należy podkreślić, że zwyczajowe prawo Maorysów (tikanga) posiada de iure pozycję normy o charakterze ius cogens. Wszelkie orzeczenia sądów i trybunałów czy akty parlamentu w Wellington lub czynności administracyjne powinny być podejmowane zgodnie z tikanga. Dotyczy to również prawa cywilnego, w tym pochówku. W ostatnich latach toczyło się kilka postępowań cywilnych między osobami pochodzenia maoryskiego. Ustawa o pochówku i kremacji z 1964 roku była sprzeczna z wolą rdzennych testatorów. Jednak bardzo często te tradycyjne rytuały pogrzebowe są niezgodne ze standardami prawa stanowionego. Niniejszy artykuł jest zatem próbą wykazania trudności w prawie cywilnym Nowej Zelandii. Temat ten zyskał na znaczeniu wraz z większą świadomością społeczeństwa obywatelskiego i szerszymi możliwościami kontaktu (zarówno prawnego, jak i pozasądowego) z państwem.
Rozważania nad zrównaniem pozycji prawnej kościołów i innych związków wyznaniowych oraz niereligijnych organizacji światopoglądowych
Authors: Bernaciński Łukasz
Published: September 2020

Niniejszy artykuł stanowi próbę odpowiedzi na pytanie o istnienie przesłanek przemawiających za obligatoryjnym zrównaniem pozycji prawnej kościołów i innych związków wyznaniowych oraz niereligijnych organizacji światopoglądowych. W tym celu przeanalizowany zostanie status prawny badanych podmiotów w prawie polskim, stosunek Unii Europejskiej do rozbieżności występujących w tym zakresie oraz funkcje, jakie badane podmioty wypełniają wobec swych członków. Kontekst dla rozważań stanowią projekty ustaw powstałe w latach 2013–2019 dotyczące zastąpienia Funduszu Kościelnego obywatelskim odpisem podatkowym na rzecz kościołów i innych związków wyznaniowych oraz przyznania niereligijnym organizacjom światopoglądowym prawa do stałego, instytucjonalnego dialogu z państwem.
Cognição e relevância: uma análise pragmática da loucura quijotesca
Authors: Dos Santos Sebastião Lourenço , Caminha Letícia Dos Santos
Published: September 2020

Analisamos o comportamento patológico do personagem cervantino, Don Quijote, a partir da perspectiva da Teoria da Relevância (SPERBER; WILSON, 2001). Abordamos a loucura quijotesca como consequência de um enviesamento cognitivo decorrente da relação “custo-benefício” sob a qual trabalha a mente humana na interpretação do significado de novas informações. A análise parte das situações comunicativas narradas nos capítulos IV, VIII, XVIII, XXI e XXII da primeira parte do romance El Ingenioso Hidalgo Don Quijote de la Mancha, cujo protagonista desenvolve uma patologia mental após a intensa e contínua leitura de novelas de cavalaria, a mudança de sua conduta é evidenciada na restrição dos contextos aos quais ele recorre para interpretar o significado das informações que processa em suas interações. Assim sendo, os delírios de Don Quijote apresentam-se como disfunções pragmáticas, que podem ser explicadas pelo Princípio de Relevância que orienta a mente humana a processar apenas as informações mais relevantes.
Infodemia em tempos de pandemia: batalhas invisíveis com baixas imensuráveis
Authors: Andersen Angélica , Godoy Elena
Published: September 2020

: Este artigo trata do fenômeno mundial da desinformação que inspirou a expressão “infodemia” durante a pandemia mundial de COVID-19; enquanto um contamina o corpo, o outro contamina as ideias. A ascensão da internet e a popularização das plataformas de mídia social mudaram o ecossistema da informação. O acesso direto a um volume exponencial de conteúdo torna difícil distinguir informações precisas de conteúdos de baixa qualidade, falsos, editoriais e sátiras. Analisamos a aderência à desinformação levando em conta a Teoria da Relevância (SPERBER e WILSON, 1986/1995), Vigilância Epistêmica (SPERBER et al., 2010), estudos sobre Racionalidade (MERCIER, 2020), conceitos de Base Comum (CLARK, 1996, 1998), estudos em economia e psicologia comportamental de Tversky (1973) e Kahneman (2002/2011), bem como estudos sobre desinformação de McIntyre (2018), Rand (2020) e Wardle (2018, 2019).
Patrimônio histórico edificado dos caminhos das tropas na região do Extremo Sul catarinense
Authors: Campos Juliano Bittencourt , Zilli Edson , Paulo Matias Carlos Dos Passos , Santos Marcos César Pereira , Da Silveira Paola Vieira , Ladwig Nilzo Ivo
Published: September 2020

O artigo busca evidenciar os caminhos utilizados pelos tropeiros entre os séculos XVII e XX em 25 municípios localizados na região do extremo sul catarinense, por meio do registro de bens materiais relacionados à atividade tropeirista. Foi utilizado levantamento documental e bibliográfico pertinente ao tema bem como entrevistas e visita na área de estudo no intuito de coletar e registrar informações nas instituições municipais. Elementos do patrimônio construído foram registrados em 6 municípios, além de relatos de rotas de passagem no território. Os resultados possibilitaram perceber que o movimento tropeirista foi importante para o povoamento da região sul, além de contribuir para a integração entre as regiões
Trança de gente: os desdobramentos da memória em Bisa Bia, Bisa Bel, de Ana Maria Machado
Authors: De Freitas Beatris Pizzoni , Oliveira Eloisa Da Rosa
Published: September 2020

O presente trabalho realizou uma análise do livro Bisa Bia, Bisa Bel (2001), da autora Ana Maria Machado, por meio dos desdobramentos da memória, tendo como foco a construção de identidade e o movimento de rememoração presentes na obra. Para isso, utilizou-se como principal suporte teórico os autores Stuart Hall (2003; 2014; 2019) no que diz respeito aos estudos identitários e Walter Benjamin (2019) no que tange os estudos da rememoração, abrindo espaço para os lampejos de perigo e a ideia de progresso que se encontram na narrativa, entre outros autores. A metodologia da pesquisa foi de cunho bibliográfico e a análise do corpus qualitativa, construída na concomitância entre a revisão teórica e a análise da obra. Por meio deste estudo, buscou-se compreender a memória não só como imagem fragmentada, mas sim, como espaço de rememoração, de ação e de construção identitária.
(Des)entedimentos e integração: o acesso à língua pelo imigrante forçado
Authors: Borba Correio Carla Aparecida Marinho
Published: September 2020

A partir das discussões sobre língua, discurso e ideologia oriundas do dispositivo teórico-analítico da Análise do Discurso de linha francesa (AD), este estudo objetiva investigar a relação entre a língua e o processo de integração de imigrantes forçados no país de destino. Baseados na análise dos relatos de uma família síria, pretendemos problematizar a questão imigratória, que ganhou destaque na agenda global na última década, em uma perspectiva que leva em consideração as dificuldades enfrentadas pelo sujeito imigrante para acessar a(s) língua(s) que constitue(m) o desafio de pertencer a um novo lugar
Unusual Skin Metastasis from Gastric Cancer: A Case Report
Authors: Budipramana Vicky Sumarki
Published: September 2020

Background: Skin metastasis from gastric cancer are relatively rare, but they have important clinical significance because they usually indicate a worse prognosis. Skin metastasis from gastric cancer may spread through lymphatic ducts, blood vessels in the ligamentum teres, contiguous extension, or embryologic remnants of the umbilicus. Purpose: To report an unusual skin metastasis from gastric cancer that clinically resembles as a benign lesion of skin papules. Case: A rare metastasis from gastric cancer origin in a 61-year-old male in the abdominal skin. Gastric cancer metastasis in an unusual site such as the abdominal skin often resembles as dermatitis, especially in the early course of metastatic spreading, which looked like common papules on the skin. Discussion: In the beginning, the skin papules were not suspected to be a metastatic process because there was no palpable or no tenderness in the subcutan or fascia underneath. The appearance resembled common dermatitis. However, as papules rapidly spread to the surrounding skin, the malignancy was then suspected. The incisional biopsy from the papules was performed and showed that it was metastatic diffuse-type gastric adenocarcinoma. Conclusion:  The skin metastasis was different from general nodules, but rather as skin papules of general dermatitis in initial appearance. The surgeon and dermatologist should be alert if they find any benign appearance of a skin lesion on the abdominal wall in a patient with a history of gastric cancer surgery.
PROFILE OF EPILEPSY PATIENTS IN THE PEDIATRIC WARD AT DR. SOETOMO GENERAL HOSPITAL, SURABAYA IN THE PERIOD OF JANUARY-DECEMBER 2017
Authors: Sekarsari Dewi , Kalanjati Viskasari P. , Machin Abdulloh , Gunawan Prastiya I.
Published: September 2020

Background: Various risk factors of epilepsy in children had been reported although differences were found amongst regions. Objective: To determine the differences in risk factors and type of epilepsy patients with febrile seizure history in children aged 0-17 years old at the Pediatric Ward, Dr. Soetomo General Hospital, Surabaya in 2017. Material and method: This is a cross sectional retrospective study, using secondary data from medical records of epilepsy patients with febrile seizure history in children aged 0-17 years old at Pedicatric Ward, Dr. Soetomo General Hospital, Surabaya in the period of January-December 2017. Data analysis was done using t-test and the Chi-Square test (Microsoft Excel 2007 and SPSS 22); level of significance was p<0.05. Result: Seventy-four male and 38 female patients were included. Febrile seizure history is observed in 42 patients and there was no significant difference between febrile seizure history and prevalence of epilepsy. The general type of seizure was found in 79 patients; mostly from Surabaya and the parents’ occupation is private employee. The most observed type of seizure is general type. Conclusion: In this study, epilepsy was predominance in males than females; and significantly more patients without febrile seizure history. General type of seizure is the most common type amongst others. These patients were mostly from Surabaya, with parents' occupation was private employees.
Culinary Identification in the Banua Anyar Culinary Tourism Area; a Contribution for Tourism in Banjarmasin City
Authors: Abbas Ersis Warmansyah , Jumriani Jumriani
Published: September 2020

Wisata kuliner merupakan satu bagian dari pariwisata. Beragam kuliner yang tersedia disetiap daerah dapat dikembangkan sebagai daya tarik wisata. Berbeda dengan jenis wisata lainnya, wisata kuliner mengunggulkan makanan, kepuasan rasa dan kekhasan suatu makanan maupun sajian. Di Kota Banjarmasin tersedia satu kawasan kuliner yang dikenal dengan sebutan kawasan kuliner Banua Anyar. Kawasan kuliner tersebut dikembangkan untuk mendukung pariwisata di Kota Banjarmasin. Penulisan artikel ini bertujuan untuk mengidentifikasi jenis kuliner yang tersedia di Kawasan Kuliner Banua Anyar. Pendekatan kualitatif dengan metode deskripstif digunakan pada penelitian. Pengumpulan data dilakukan dengan wawancara, observasi dan dokumentasi. Analisis data dilakukan dengan mereduksi data, penyajian data dan verifikasi. Hasil penelitian mengidentifikasi bahwa jenis kuliner di kawasan kuliner Banua Anyar terdiri dari makanan pokok, lauk pauk dan kue tradisioanal. Beragam jenis kuliner tersebut tersedia di 14 stand usaha kuliner di kawasan kuliner Banua Anyar untuk mendukung pengembangan pariwisata di Kota Banjarmasin.
The Strengthening of Discipline Value in Education Training Activities in Rindam VI/Mulawarman as a Learning Resources on Social Studies
Authors: Hermansyah Hermansyah , Syaharuddin Syaharuddin , Mutiani Mutiani
Published: September 2020

Penelitian ini bertujuan untuk mendeskripsikan nilai disiplin pada aktivitas pelatihan pendidikan di Rindam VI/Mulawarman dan signifikansinya dalam pembelajaran IPS di sekolah sebagai sumber belajar. Pendekatan kualitatif dan metode deskriptif digunakan dalam penelitian. Adapun teknik pengumpulan data melalui tiga langkah, yaitu; observasi partisipatif, wawancara, dan studi dokumentasi. Model Miles dan Hubermen dipilih untuk menganalisis data dengan tahapan; reduksi data, penyajian data, dan verifikasi data sebagai penarikan kesimpulan. Keabsahan data melalui perpanjangan waktu pengamatan, triangulasi, member check sehingga menghasilkan data jenuh. Hasil penelitian mendeskripsikan bahwa nilai disiplin pada aktivitas pelatihan pendidikan di Rindam VI/Mulawarman dapat dilihat bahwa peserta didik mematuhi aturan dan tata tertib, ketepatan waktu, menjaga kebersihan, dan berpakaian rapi. Nilai disiplin tersebut memiliki signifikansi dalam pendidikan IPS dalam menjadikan warga negara yang baik dengan diintegrasikan ke dalam pembelajaran IPS di sekolah.
The Influence of Social Capital on Skills Social Cooperation (Study on the Organization of Santri Darul Hijrah Putri Cindai Alus)
Authors: Olfah Rasyidah , Syaharuddin Syaharuddin , Hasanah Mahmudah
Published: September 2020

Persaingan dalam lingkup global semakin ketat sehingga setiap orang dituntut untuk mempunyai keterampilan agar mampu terjun ke dunia pekerjaan. Keterampilan yang harus dimiliki yaitu keterampilan hard skilll dan soft skill salah satunya adalah kerjasama. Kerjasama dapat dilakukan melalui sebuah organisasi, serta dianggap sebagai wadah untuk mendapat sumber daya yang baru.  Penelitian kuantitatif dengan metode analisis deskriptif kuantitatif persentase digunakan dalam penelitian ini untuk menggambarkan pengaruh modal sosial terhadap kerjasama dalam organisasi Santri Darul Hijrah Putri Cindai Alus. Teknik pengumpulan data dilakukan dengan pembagian angket kepada sampel penelitian yaitu anggota pengurus OSDA sejumlah 156 orang, dokumentasi serta wawancara dan melihat secara langsung proses kerjasama pada OSDA. Selanjutnya dilakukan uji instrumen melalui uji validitas dan reliabilitas. Setelah itu pada tahap uji prasyarat analisis penelitian dilakukan uji normalitas dan uji linearitas. Teknis analisis data yang digunakan pada penelitian ini yaitu uji distribusi persentase dan uji regresi linear sederhana. Hasil penelitian menunjukkan bahwa Kriteria pengujian HO diterima apabila r hitung < r tabel, karena analisis r hitung  > r tabel = 0,676 > 0,157 sehingga hipotesis ditolak (Ho) dan hipotesis diterima (Ha). Adapun untuk signifikan 0,000 < 0,005 jadi dapat disimpulkan bahwa modal sosial berpengaruh secara signifikan terhadap kerjasama santriwati dalam organisasi santri Darul Hijrah putri Cindai Alus.
Manajemen Pembelajaran Musik Siswa MIS (Manado Internasional School) secara virtual di Era Kenormalan Baru
Authors: Kaunang Meyny S. C.
Published: September 2020

IntisariPenelitian ini di lakukan pada sekolah MIS (Manado Internasional School), yang memiliki latarbelakang budaya yang berbeda sehing-ga menjadikan pembelajaran dalam kelas menjadi saling mengisi. Manajemen pembelajaran yang diterapkan pada masa pandemik Covid-19 lebih pada bentuk virtual, atau jaga jarak apabila ber-tatap muka. Manajemen yang dilaksanakan pada pembelajaran ini bertujuan agar siswa lebih cepat dalam menerima pembelajaran musik. Metode yang digunakan dalam penelitian ini adalah metode diskriptif-kualitatif. Pengumpulan data menggunakan trigulasi. Ob-servasi dilakukan sesuai dengan protokol kesehatan, wawancara dilakukan dengan jaga jarak dan secara virtual, melalui aplikasi Zoom Cloud Meetings atau video call. Hasil penelitian ini menun-jukkan bahwa manajemen pembelajaran musik  di MIS dalam masa pandemik Covid-19 atau Era Kenormalan Baru dilaksanakan dalam bentuk virtual. Media pembelajaran yang digunakan untuk penun-jang siswa dalam berlatih mandiri adalah media youtube. Hasil pembelajaran ini diketahui lebih efektif dalam hal melatih kepekaan siswa bisa, dan mereka pun dapat dikontrol secara ber-ulang-ulang.Kata kunci:  pembelajaran musik, permbelajaran virtual, era kenormalan baru, manado internasional school AbstractThis research was conducted at the MIS (Manado International School) school, which has different cultural backgrounds so that learning in the classroom is complementary. Learning management that was applied during the Covid-19 pandemic was more in a vir-tual form, or maintaining a distance when face to face. Manage-ment carried out in this learning aims to make students accept music learning more quickly. The method used in this research is descriptive-qualitative method. Data collection using trigulation. Ob-servers were carried out in accordance with health protocols, interviews were conducted in a distance and virtually, via the Zoom Cloud Meetings application or video call. The results of this study indicate that the management of music learning in MIS during the Covid-19 pandemic or the New Normal Era was implemented in vir-tual form. The learning media used to support students in prac-ticing independently is the youtube media. The learning outcomes are known to be more effective in terms of training students' sensi-tivity, and they can be controlled repeatedly.Keywords: music learning, virtual learning, new normal era, manado international school
DIAGNÓSTICO DE ENFERMAGEM TENSÃO DO PAPEL DE CUIDADOR EM FAMILIARES DE PESSOAS COM FERIDAS CRÔNICAS
Authors: Da Silva Kezia Juliana , Lopes Dias Julliany , Gomes da Silva Neto Maurício , Da Silva Oliveira Araújo Henrique , Martins Bastos Amanda , Andrade Martins Marlene , Rodrigues Alves Montefusco Selma , Pereira Ângela Lima
Published: September 2020

O cuidado da pessoa com ferida crônica é complexo, e sob responsabilidade da família gera demandas que podem resultar em cansaço e desgaste do cuidador, que é apresentado na NANDA-I como tensão no papel de cuidador. O objetivo foi analisar a ocorrência do diagnóstico de enfermagem (DE) tensão do papel de cuidador em familiares de pessoas com feridas crônicas. Trata-se de um estudo descritivo exploratório, realizado em 2019, por meio de entrevista semiestruturada com pessoas que cuidam de um familiar com ferida crônica em Palmas-Tocantins. Análise de variáveis quantitativas realizada por estatística descritiva, e de variáveis subjetivas por “agrupamento de dados” e “interpretação do agrupamento”. Identificados 6 cuidadores com DE tensão no papel de cuidador, com predomínio do sexo feminino, grau de parentesco de filhos e cônjuges. Os principais fatores relacionados foram: excesso de atividades de cuidado, crise financeira e o prejuízo à saúde. A principal característica definidora foi a falta de tempo para atender às necessidades pessoais. Tensão no papel de cuidador em familiares de pessoas com feridas crônicas gera implicações significativas na saúde e dinâmica de vida dos cuidadores. Assim, tornam-se necessárias políticas de saúde que atendam não apenas a população com ferida crônica, mas também a família.

Palavras-chave: Relações familiares; Diagnóstico de Enfermagem; Ferimentos e lesões.
COMPARAÇÃO DE MÉTODOS DE EXTRAÇÃO DE RNA APLICADOS A CULTURAS AMILÁCEAS UTILIZADAS NA PRODUÇÃO DE ETANOL
Authors: Rodrigues de Soouza Micaele , Duarte de Oliveira Gabriel , Esteves dos Santos Ana Elisa , Aparecida Ságio Solange
Published: September 2020

A crescente preocupação com os efeitos provenientes do uso de combustíveis fosseis, devido à grande dependência dos mesmos, tem proporcionado nas últimas décadas estudos mais intensos sobre biocombustíveis, bem como a diversificação de matérias primas. Atualmente o maior produtor mundial de etanol é os Estados unidos e a matéria prima majoritária utilizada para este fim é a cultura do milho. Entretanto, tem se buscado uma maior diversificação de matérias primas, intensificando-se os estudos voltados para culturas como a mandioca e a batata-doce. Visando a obtenção de cultivares com alto potencial energético, a engenharia genética é considerada uma ferramenta indispensável, já que o melhoramento tradicional tem sido um desafio para diversas culturas. Entre as várias técnicas aplicadas, estão os estudos moleculares transcricionais, que possuem como a primeira etapa a extração do RNA, sendo este um fator limitante em análises moleculares, por ser a base para estudos posteriores. Nesta revisão consta um levantamento dos métodos mais empregados para o isolamento do RNA das culturas do milho, mandioca e batata-doce e uma análise de custo/benefício. Concluindo-se que o método menos dispendioso e que mantem qualidade e quantidade de RNA são os protocolos que tiveram suas adaptações a partir do método de CTAB.