bluuebunny/crossref_metadata_2025 huggingface dataset:
Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice
Authors: Evert K. , Kocher T. , Schindler A. , Müller M. , Müller K. , Pink C. , Holtfreter B. , Schmidt A. , Dombrowski F. , Schubert A. , von Woedtke T. , Rupf S. , Calvisi D. F. , Bekeschus S. , Jablonowski L.
Published: October 2021

Peri-implantitis may result in the loss of dental implants. Cold atmospheric pressure plasma (CAP) was suggested to promote re-osseointegration, decrease antimicrobial burden, and support wound healing. However, the long-term risk assessment of CAP treatment in the oral cavity has not been addressed. Treatment with two different CAP devices was compared against UV radiation, carcinogen administration, and untreated conditions over 12 months. Histological analysis of 406 animals revealed that repeated CAP exposure did not foster non-invasive lesions or squamous cell carcinoma (SCCs). Carcinogen administration promoted non-invasive lesions and SCCs. Molecular analysis by a qPCR screening of 144 transcripts revealed distinct inflammatory profiles associated with each treatment regimen. Interestingly, CAP treatment of carcinogen-challenged mucosa did not promote but instead left unchanged or reduced the proportion of non-invasive lesions and SCC formation. In conclusion, repeated CAP exposure of murine oral mucosa was well tolerated, and carcinogenic effects did not occur, motivating CAP applications in patients for dental and implant treatments in the future.
Radiologic-pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose
Authors: Chelales Erika , Morhard Robert , Nief Corrine , Crouch Brian , Everitt Jeffrey I. , Sag Alan Alper , Ramanujam Nirmala
Published: October 2021

Ethanol provides a rapid, low-cost ablative solution for liver tumors with a small technological footprint but suffers from uncontrolled diffusion in target tissue, limiting treatment precision and accuracy. Incorporating the gel-forming polymer ethyl cellulose to ethanol localizes the distribution. The purpose of this study was to establish a non-invasive methodology based on CT imaging to quantitatively determine the relationship between the delivery parameters of the EC-ethanol formulation, its distribution, and the corresponding necrotic volume. The relationship of radiodensity to ethanol concentration was characterized with water–ethanol surrogates. Ex vivo EC-ethanol ablations were performed to optimize the formulation (n = 6). In vivo ablations were performed to compare the optimal EC-ethanol formulation to pure ethanol (n = 6). Ablations were monitored with CT and ethanol distribution volume was quantified. Livers were removed, sectioned and stained with NADH-diaphorase to determine the ablative extent, and a detailed time-course histological study was performed to assess the wound healing process. CT imaging of ethanol–water surrogates demonstrated the ethanol concentration-radiodensity relationship is approximately linear. A concentration of 12% EC in ethanol created the largest distribution volume, more than eight-fold that of pure ethanol, ex vivo. In vivo, 12% EC-ethanol was superior to pure ethanol, yielding a distribution volume three-fold greater and an ablation zone six-fold greater than pure ethanol. Finally, a time course histological evaluation of the liver post-ablation with 12% EC-ethanol and pure ethanol revealed that while both induce coagulative necrosis and similar tissue responses at 1–4 weeks post-ablation, 12% EC-ethanol yielded a larger ablation zone. The current study demonstrates the suitability of CT imaging to determine distribution volume and concentration of ethanol in tissue. The distribution volume of EC-ethanol is nearly equivalent to the resultant necrotic volume and increases distribution and necrosis compared to pure ethanol.
Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2
Authors: Takahata Yoshifumi , Hagino Hiromasa , Kimura Ayaka , Urushizaki Mitsuki , Kobayashi Sachi , Wakamori Kanta , Fujiwara Chika , Nakamura Eriko , Yu Kayon , Kiyonari Hiroshi , Bando Kana , Murakami Tomohiko , Komori Toshihisa , Hata Kenji , Nishimura Riko
Published: October 2021

Runx2 is an essential transcription factor for bone formation. Although osteocalcin, osteopontin, and bone sialoprotein are well-known Runx2-regulated bone-specific genes, the skeletal phenotypes of knockout (KO) mice for these genes are marginal compared with those of Runx2 KO mice. These inconsistencies suggest that unknown Runx2-regulated genes play important roles in bone formation. To address this, we attempted to identify the Runx2 targets by performing RNA-sequencing and found Smoc1 and Smoc2 upregulation by Runx2. Smoc1 or Smoc2 knockdown inhibited osteoblastogenesis. Smoc1 KO mice displayed no fibula formation, while Smoc2 KO mice had mild craniofacial phenotypes. Surprisingly, Smoc1 and Smoc2 double KO (DKO) mice manifested no skull, shortened tibiae, and no fibulae. Endochondral bone formation was also impaired at the late stage in the DKO mice. Collectively, these results suggest that Smoc1 and Smoc2 function as novel targets for Runx2, and play important roles in intramembranous and endochondral bone formation.
Delivery of gefitinib in synergism with thymoquinone via transferrin-conjugated nanoparticle sensitizes gefitinib-resistant non-small cell lung carcinoma to control metastasis and stemness
Authors: Upadhyay Priyanka , Ghosh Avijit , Basu Arijita , Pranati P. A. , Gupta Payal , Das Shaswati , Sarker Sushmita , Bhattacharjee Mousumi , Bhattacharya Saurav , Ghosh Swatilekha , Chattopadhyay Sreya , Adhikary Arghya
Published: October 2021

The NP-Dual-3 causes the pH-dependent release of gefitinib and thymoquinone, which breaks the shield of the CSC niches, reduce cell migration and stemness in A549/GR cells by degradation of HIF1-α and downregulation of miR-21.
Differences in the torsional anharmonicity between reactant and transition state: the case of 3-butenal + H abstraction reactions
Authors: Passos Maiara Oliveira , Lins Igor Araujo , Venâncio Mateus Fernandes , Alves Tiago Vinicius
Published: October 2021

Thermal rate coefficients for the hydrogen-abstraction reactions of 3-butenal by a hydrogen atom were obtained by applying multipath canonical variational theory with small-curvature tunneling (MP-CVT/SCT).
Pivotal role of H2 in the isomerisation of isosorbide over a Ru/C catalyst
Authors: Hu H. , Ramzan A. , Wischert R. , Jerôme F. , Michel C. , de Olivera Vigier K. , Pera-Titus M.
Published: October 2021

DFT calculations combined with experiments unveil the key role of the H2 coverage on Ru/C catalyst in the isomerization of isosorbide.
Synthesis and biological evaluation of mixed-ligand cyclometalated iridium(iii)–quinoline complexes
Authors: Yang Yan , Wang Cheng-Ming , Pan Feng-Hua , Qin Qi-Pin , Xie Qiu-Ji , Chen Qing , Liang Hong
Published: October 2021

Cyclometalated Ir(iii)–quinoline complexes 2a–2f induce A549/DDP cell apoptosis. In addition, 2e showed remarkable tumour growth suppression (ca.64.1%).
Dual-phase glass ceramics for dual-modal optical thermometry through a spatial isolation strategy
Authors: Li Xinyue , Chen Youli , Yang Tao , Zhu Yiwen , Mao Qinan , Zhong Jiasong , Li Shichen
Published: October 2021

Remarkable dual-modal luminescence is realized by dual-phase glass ceramics through a spatial isolation strategy.
Ionic indium(iii) chloride hybrids incorporating a 2,2′-bipyrimidine ligand: studies on photoluminescence and structural transformation
Authors: Jin Jian-Ce , Zhuang Ting-Hui , Lin Yang-Peng , Lin Bing-Ye , Jiang Jiang , Du Ke-Zhao , Huang Xiao-Ying
Published: October 2021

The first three indium(iii) chloride hybrids composed of a 2,2′-bipyrimidine-incorporating haloindium(iii) anion and ionic liquid cations were synthesized and structurally studied, which show structural transformation and photoluminescence switching.
Biomimetically synthesized luminescent Tb3+-doped fluorapatite/agar nanocomposite for detecting UO22+, Cu2+, and Cr3+ions
Authors: Liu Hongjuan , Wang Xianli , Abeywickrama Thulitha , Jahanbazi Forough , Min Zefu , Lee ZhengRong , Terry Jeff , Mao Yuanbing
Published: October 2021

Biodegradable rare earth doped fluorapatite has been developed as a luminescence probe for the detection of both radioactive and nonradioactive ions.
Prediction of NDMA formation potential using non-target analysis data: a proof of concept
Authors: Sanchís Josep , Petrović Mira , Farré Maria José
Published: October 2021

In the present study we coupled nontarget analyses data and predictive models in order to estimate the formation potential of NDMA, a nitrogenous disinfection by-product that has been included in drinking water regulations worldwide.
Cardamonin inhibits osteogenic differentiation of human valve interstitial cells and ameliorates aortic valve calcification via interfering in the NF-κB/NLRP3 inflammasome pathway
Authors: Wang Chunli , Xia Yi , Qu Linghang , Liu Yanju , Liu Xianqiong , Xu Kang
Published: October 2021

Cardamonin (CDM) is a natural chalcone with strong anti-inflammatory properties. CDM ameliorates aortic valve calcification by inhibiting the phenotypical calcific transformation of hVICs via mediating the inactivation of the NF-κB/NLRP3 inflammasome.
Structural characterization of polysaccharide purified from Amanita caesarea and its pharmacological basis for application in Alzheimer's disease: endoplasmic reticulum stress
Authors: Hu Wenji , Li Zhiping , Wang Wenqi , Song Minkai , Dong Ruitao , Zhou Yulin , Li Yu , Wang Di
Published: October 2021

The structural characterization and the anti-AD activities via regulation on oxidative stress-mediated endoplasmic reticulum stress of the polysaccharide purified from Amanita caesarea.
Bread breakdown pathways during mastication: impact of wheat bran fortification
Authors: Lin Suyun , Jin Xiaoxuan , Gao Jing , Kim Esther H.-J. , Morgenstern Marco P. , Dong Zhizhong , Ying Jian , Shao Danqing , Zhao Qian , Song Xiaoming , Zhou Weibiao
Published: October 2021

Wheat bran fortification changed the bread breakdown pathways during mastication.
The mechanism of delaying starch digestion by luteolin
Authors: Zhao Yiling , Wang Ming , Zhang Jinsheng , Xiong Chunhong , Huang Ganhui
Published: October 2021

The mechanisms of luteolin delaying starch digestion by two methods, inhibiting α-amylase and binding with starch directly, were studied.
circ01592 regulates unsaturated fatty acid metabolism through adsorbing miR-218 in bovine mammary epithelial cells
Authors: Chen Zhi , Cao Xiang , Lu Qinyue , Zhou Jingpeng , Wang Yuhao , Wu Yanni , Mao Yongjiang , Xu Huifen , Yang Zhangping
Published: October 2021

The present study analyzed the effect and regulatory mechanism of circ01592/miR-218/ELOVL5 on fatty acid synthesis, clarified the molecular regulatory mechanism of milk fatty acid synthesis.
Visible LED-based photo-redox properties of sulfur and nitrogen-doped carbon dots designed by solid-state synthesis
Authors: Kaushal Neha , Sharma Amit L. , Saha Avishek
Published: October 2021

Carbon dots were synthesized using solvent-free, microwave synthesis and photoreduction of methyl viologen was studied under visible wavelength light irradiation.
Scattering versus fluorescence self-quenching: more than a question of faith for the quantification of water flux in large unilamellar vesicles?
Authors: Wachlmayr Johann , Hannesschlaeger Christof , Speletz Armin , Barta Thomas , Eckerstorfer Anna , Siligan Christine , Horner Andreas
Published: October 2021

Accurate pf values are of utmost importance to understand the structure–function relationship of water permeation through membrane channels, guiding the design of artificial or biological water channels for separation applications.
Design principles of noble metal-free electrocatalysts for hydrogen production in alkaline media: combining theory and experiment
Authors: Jung Hyeonjung , Choung Seokhyun , Han Jeong Woo
Published: October 2021

This review discusses the rational design of efficient electrocatalysts by understanding alkaline hydrogen evolution reaction and oxygen evolution reaction mechanisms, as achieved by combining experimental and computational approaches.
Investigation of ZIF-derived Co, N co-doped porous carbon-supported Au nanoparticles as an effective catalyst for borohydride electrooxidation
Authors: Yi Lanhua , Peng Xiaoqin , Ma Xiao , Gao Yan , Wang Xianyou , Lu Yebo
Published: October 2021

An Au/CoNPC nanoparticle composite electrocatalyst with lower cost and higher catalytic activity would be a promising anode for direct borohydride fuel cells.
Sulfate-functionalized metal–organic frameworks supporting Pd nanoparticles for the hydrogenolysis of glycerol to 1,2-propanediol
Authors: Zhang Jingzheng , Li Zhe , He Xuefeng , Cao Yonghua , Wang Cheng
Published: October 2021

Installing sulfate and Pd in MOF-808 achieved glycerol conversion to 1,2-PDO via selective hydrogenolysis.
Room temperature ethanol gas-sensing properties based on Ag-doped MoSe2 nanoflowers: experimental and DFT investigation
Authors: Li Tingting , Yu Sujing , Li Qi , Chi Minghe , Li Peng
Published: October 2021

Nanoflower-like Ag-doped MoSe2 nanocomposites were prepared by a simple hydrothermal method for room-temperature ethanol detection with enhanced sensing performance.
Surface band bending and carrier dynamics in colloidal quantum dot solids
Authors: Clark Pip C. J. , Lewis Nathan K. , Ke Jack Chun-Ren , Ahumada-Lazo Ruben , Chen Qian , Neo Darren C. J. , Gaulding E. Ashley , Pach Gregory F. , Pis Igor , Silly Mathieu G. , Flavell Wendy R.
Published: October 2021

Evidence for band bending in colloidal quantum dot (CQD) solids is shown using photoemission surface photovoltage measurements, and carrier dynamics for a range of CQD solids are measured, correlating the results to surface chemistry.
Oxidative electro-organic synthesis of dimeric hexahydropyrrolo-[2,3-b]indole alkaloids involving PCET: total synthesis of (±)-folicanthine
Authors: Shaw Kundan , Sharma Sulekha , Khatua Arindam , Paul Amit , Bisai Alakesh
Published: October 2021

An efficient electrochemical oxidation strategy for the total synthesis of (±)-folicanthine (1b), has been envisioned. Control experiments suggest that a PCET pathway involving stepwise ET-PT was involved in the key oxidative dimerization process.
An expeditious and highly efficient synthesis of substituted pyrroles using a low melting deep eutectic mixture
Authors: Alvi Shakeel , Ali Rashid
Published: October 2021

An expeditious green method for the synthesis of diverse valued substituted pyrroles through a Paal–Knorr condensation reaction has fruitfully been revealed.
Hydrogen bonding interactions can decrease clar sextet character in acridone pigments
Authors: Wen Zhili , Karas Lucas José , Wu Judy I-Chia
Published: October 2021

Magnetic evaluations of aromaticity suggest that hydrogen bonding interactions can perturb the Clar sextet characters of acridones, which have implications for their electronic properties.
Polymer based nanoparticles for biomedical applications by microfluidic techniques: from design to biological evaluation
Authors: Fabozzi Antonio , Della Sala Francesca , di Gennaro Mario , Solimando Nicola , Pagliuca Maurizio , Borzacchiello Assunta
Published: October 2021

The development of microfluidic technologies represents a new strategy to produce and test drug delivery systems.
High electron mobility and transverse negative magnetoresistance in van der Waals material Nb2GeTe4
Authors: Han Xue , Guo Zhongnan , Chen Long , Cao Cheng , Sun Fan , Wang Gang , Yuan Wenxia
Published: October 2021

Chemical vapor transport method was used to grow high quality Nb2GeTe4 single-crystals, which shows remarkably high electron mobility, 424.37 cm2 V−1 s−1, at room temperature and an unusual large unsaturated negative magnetoresistance below 10K.
A low-cost 2D WO3/Ni3S2 heterojunction for highly stable hydrogen evolution
Authors: Sun Tongming , Zhong Weiting , Zhang Mengke , Tang Yanfeng , Wang Jin , Xu Chen , Hu Lanping , Wang Minmin
Published: October 2021

A WO3/Ni3S2 heterojunction electrode is developed, which exhibits higher electrical/ionic conductivity and catalytic activity and stability due to the specific cooperativity. It also shows high hydrogen evolution performance both at low and high current densities.
Ring-closing metathesis of N-alkenyl-cyanamides
Authors: Dewez Damien F. , Diacofotaki Christina , Evano Gwilherm
Published: October 2021

An entry to new classes of nitrogen-containing heterocycles featuring both a cyanamide and an unsaturated 5-, 6- or 7-membered ring is reported by RCM of the corresponding N-alkenyl-cyanamides, new partners for olefin metathesis.
Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface
Authors: Wang Liyong , Wang Zhenghao , Wang Zhiwen , Zhang Chunyang , Wu Yongling , Zheng Hongyu
Published: October 2021

Ag-doped ZnO nanocrystals are incorporated into LIG for enhancing the antibacterial effect. The formulated nanocrystals act as an effective and biocompatible antibacterial agent and yet have a much reduced and acceptable level of Ag concentration.
Antioxidant activity of SSeCAHK in HepG2 cells: a selenopeptide identified from selenium-enriched soybean protein hydrolysates
Authors: Zhang Jian , Zhang Qiyue , Li He , Chen Xinwei , Liu Wanlu , Liu Xinqi
Published: October 2021

Se-containing antioxidative soybean peptides were isolated and identified as SSeCAHK. The SSeCAHK had protective effects against H2O2-induced oxidative stress in HepG2 cells and could be used as a natural food-born antioxidant.
A highly conductive quasi-solid-state electrolyte based on helical silica nanofibers for lithium batteries
Authors: Hu Jiemei , Wang Haoran , Yang Yonggang , Li Yi , Wu Qi-hui
Published: October 2021

A quasi-solid-state electrolyte of high-ionic conductivity is constructed from an inorganic matrix composed of helical silica nanofibers (HSNFs) derived from the self-assembly of chiral gelators.
The Monte Carlo approach to model and predict the melting point of imidazolium ionic liquids using hybrid optimal descriptors
Authors: Lotfi Shahram , Ahmadi Shahin , Kumar Parvin
Published: October 2021

The melting points of imidazolium ILs are studied employing a quantitative structure–property relationship (QSPR) approach to develop a model for predicting the melting points of a data set of imidazolium ILs.
N and S co-doped graphene enfolded Ni–Co-layered double hydroxides: an excellent electrode material for high-performance energy storage devices
Authors: Khan Firoz
Published: October 2021

A novel graphene embedded Ni–Co-LDH electrode was developed. The charge transportation rate was enhancedviaN and S heteroatom doping, which results in an excellent discharge capacitance of 2193 F g−1at 5 A g−1.
Facile synthesis of novel NH2-MIL-53(Fe)/AgSCN heterojunction composites as a highly efficient photocatalyst for ciprofloxacin degradation and H2 production under visible-light irradiation
Authors: Yi Jungang , Wu Xianghui , Wu Huadong , Guo Jia , Wu Kun , Zhang Linfeng
Published: October 2021

A novel NH2-MIL-53(Fe)/AgSCN composite photocatalyst was successfully prepared by a one-step chemical precipitation method, the composite show high photocatalytic activity for antibiotics degradation and H2 evolution under visible light irradiation.
Improvement of the antimicrobial potency, pharmacokinetic and pharmacodynamic properties of albicidin by incorporation of nitrogen atoms
Authors: Zborovsky Lieby , Kleebauer Leonardo , Seidel Maria , Kostenko Arseni , von Eckardstein Leonard , Gombert Frank Otto , Weston John , Süssmuth Roderich D.
Published: October 2021

A systematic pyridine-scan of the albicidin molecule provides a new lead structure with improved antimicrobial properties.
Correlative 3D cryo X-ray imaging reveals intracellular location and effect of designed antifibrotic protein–nanomaterial hybrids
Authors: Groen J. , Palanca A. , Aires A. , Conesa J. J. , Maestro D. , Rehbein S. , Harkiolaki M. , Villar A. V. , Cortajarena A. L. , Pereiro E.
Published: October 2021

A novel 3D cryo correlative approach locates designed therapeutic protein–nanomaterial hybrids in whole cells with high specificity and resolution. Detection of treatment-induced morphological changes, crucial for pre-clinical studies, are revealed.
Decreasing the coordinated N atoms in a single-atom Cu catalyst to achieve selective transfer hydrogenation of alkynes
Authors: Zhang Xuge , Lin He , Zhang Jian , Qiu Yajun , Zhang Zedong , Xu Qi , Meng Ge , Yan Wensheng , Gu Lin , Zheng Lirong , Wang Dingsheng , Li Yadong
Published: October 2021

We report that the decrease of coordinated N atoms in single-Atom Cu catalyst through an oxide compounding strategy can succeed in realizing the transfer hydrogenation of alkynes with great activity and selectivity.
Jet fuel range hydrocarbon production by co-pyrolysis of low density polyethylene and wheat straw over an activated carbon catalyst
Authors: Huo Erguang , Liu Chao , Xin Liyong , Zhang Yayun , Zhao Yunfeng , Qian Moriko , Lin Xiaona , Lei Hanwu
Published: October 2021

High-efficiency and low-cost catalysts matter a great deal to convert solid wastes into high-value chemicals and biofuels.
Current progressions in transition metal based hydroxides as bi-functional catalysts towards electrocatalytic total water splitting
Authors: Kumaravel Sangeetha , Karthick Kannimuthu , Sankar Selvasundarasekar Sam , Karmakar Arun , Madhu Ragunath , Bera Krishnendu , Kundu Subrata
Published: October 2021

This review highlights the advantages of transition metal based hydroxides (TMOHs) as a better and cheaper alternative electrocatalyst materials in the total water splitting (TWS) application in terms of their activity, durability and stability.
The impact of ligands on the synthesis and application of metal halide perovskite nanocrystals
Authors: Haydous Fatima , Gardner James M. , Cappel Ute B.
Published: October 2021

The surface ligation of metal halide perovskite nanocrystals (NC) influences the size/dimensionality, optoelectronic properties, chemical stability, and use of the NCs.
Electrochemical reduction of carbon dioxide with nearly 100% carbon monoxide faradaic efficiency from vacancy-stabilized single-atom active sites
Authors: Lu Chenbao , Jiang Kaiyue , Tranca Diana , Wang Ning , Zhu Hui , Rodríguez-Hernández Fermín , Chen Zhenying , Yang Chongqing , Zhang Fan , Su Yuezeng , Ke Changchun , Zhang Jichao , Han Yu , Zhuang Xiaodong
Published: October 2021

Unsaturated Ni centers are prepared through a CO2-to-carbon process and exhibit promising performance for electrochemical CO2 reduction. As cathodes in flow cells, the catalysts exhibit nearly 100% selectivity for CO formation under a high current density of 51 mA cm−2.
Operando video microscopy of Li plating and re-intercalation on graphite anodes during fast charging
Authors: Chen Yuxin , Chen Kuan-Hung , Sanchez Adrian J. , Kazyak Eric , Goel Vishwas , Gorlin Yelena , Christensen Jake , Thornton Katsuyo , Dasgupta Neil P.
Published: October 2021

Operando video microscopy on calendared graphite electrodes presents the dynamic evolution of Li plating and re-intercalation during fast charging.
A mechanically robust all-solid-state supercapacitor based on a highly conductive double-network hydrogel electrolyte and Ti3C2Tx MXene electrode with anti-freezing property
Authors: Peng Junbo , Zhou Manhua , Gao Yafei , Wang Jianfeng , Cao Yanxia , Wang Wanjie , Wu Decheng , Yang Yanyu
Published: October 2021

A flexible all-solid-state supercapacitor based on a highly ionic conductive double-network hydrogel electrolyte and intrinsically powerful MXene film electrode revealed remarkable mechanical reliability, exceptional performance and cold tolerance.
Supported ultrafine NiPt–MoOxnanocomposites as highly efficient catalysts for complete dehydrogenation of hydrazine borane
Authors: Kang Xia , Yao Jia-Xin , Duan Yan-Xin , Chen Ze-Yu , Yan Jun-Min , Jiang Qing
Published: October 2021

A NiPt–MoOx/NH2–N-rGO nanocomposite is developed at room temperature, and it has a high dehydrogenation efficiency for hydrazine borane at 323 K.
9.63% efficient flexible Cu2ZnSn(S,Se)4 solar cells fabricated via scalable doctor-blading under ambient conditions
Authors: Xu Han , Ge Sijie , Yang Wentao , Khan Saqib Nawaz , Huang Yuxiang , Mai Yaohua , Gu Ening , Lin Xianzhong , Yang Guowei
Published: October 2021

An alternative printing via blading molecular inks with/without Na by turns in air is developed to solve the issues of Na shortage and cracks in the absorbers on Mo foil, enabling a 9.63% efficient Cu2ZnSn(S,Se)4 flexible solar cell.
Triple-cation perovskite solar cells fabricated by a hybrid PVD/blade coating process using green solvents
Authors: Siegrist Severin , Yang Shih-Chi , Gilshtein Evgeniia , Sun Xiaoxiao , Tiwari Ayodhya N. , Fu Fan
Published: October 2021

A novel and scalable PVD/blade coating method of the perovskite absorber is presented. In conjunction with charge transporting layers blade coated in ambient air using non-toxic solvents, these perovskite solar cells achieved 18.7% efficiency.
Efficient lanthanide Gd doping promoting the thermoelectric performance of Mg3Sb2-based materials
Authors: Lei Jingdan , Wuliji Hexige , Zhao Kunpeng , Wei Tian-Ran , Xu Qing , Li Peng , Qiu Pengfei , Shi Xun
Published: October 2021

By considering the electronegativity difference and mass difference between dopant and host elements, we theoretically and experimentally demonstrated Gd as an effective dopant to promote thermoelectric performance of Mg3Sb2-based materials.
Cell membrane camouflaged cerium oxide nanocubes for targeting enhanced tumor-selective therapy
Authors: Liu Zongjun , Wan Peng , Yang Mingxin , Han Fang , Wang Tianran , Wang You , Li Yu
Published: October 2021

Anticancer therapies with profound efficacy but negligible toxicity are realized via the combination of targeting and tumor-selective strategy based on cancer cell membrane-coated cerium oxide nanocubes.
Ultrafine rhenium–ruthenium nanoparticles decorated on functionalized carbon nanotubes for the simultaneous determination of antibiotic (nitrofurantoin) and anti-testosterone (flutamide) drugs
Authors: Veerakumar Pitchaimani , Vinothkumar Venkatachalam , Chen Shen-Ming , Sangili Arumugam , Lin King-Chuen
Published: October 2021

In this work, Re–Ru@f-MWCNT nanocomposite used as a new electrode platform for simultaneous electrochemical detection of nitrofurantoin (NFT) and flutamide (FLT) drugs.
Doping of a Zn-MOF with Eu3+ and Tb3+ for application in the manufacture of a WLED
Authors: Peña-Rodríguez Rodolfo , Molina-González Jorge A. , Desirena-Enrriquez Haggeo , Armenta-Jaime Erika , Rivera José María , Castillo-Blum Silvia E.
Published: October 2021

A new blue light-emitting molecular–organic framework namely FQUNAM-MOF (1) was synthesized in a simple way using formic acid and zinc nitrate as precursors.
Directly written DPP-DTT/SrTiO3organic/inorganic heterojunctions for anisotropic self-powered photodetectors
Authors: Zhang Yong , Liu Weilin , Liu Yushen , Wang Conghuan , Zhu Guodong , Song Weidong
Published: October 2021

Direct writing technique was developed to fabricate DPP-DTT/SrTiO3 photodetectors with parallel and perpendicular configurations, showing identical self-powered but anisotropic photoresponse, which exhibits great potential for broad applications.
Finely modulated asymmetric nonfullerene acceptors enabling simultaneously improved voltage and current for efficient organic solar cells
Authors: Gao Huanhuan , Wan Xiangjian , Xuan Ziyi , Ma Wei , Xin Jingming , Li Chenxi , Chen Yongsheng
Published: October 2021

An asymmetric acceptor 5T-2C8-2Cl has been designed and an efficiency of 13.02% with simultaneously improved Jsc and Voc has been achieved.
Organic-semiconductor nanoarchitectonics for multi-valued logic circuits with ideal transfer characteristics
Authors: Jo Sun-Woo , Choi Jungsoo , Hayakawa Ryoma , Wakayama Yutaka , Jung Sungyeop , Kim Chang-Hyun
Published: October 2021

A nanoarchitectonics approach to high-performance organic multi-valued logic circuits is proposed.
Toward Preventing Speech and Language Disorders of Known Genetic Origin: First Post-Intervention Results of Babble Boot Camp in Children With Classic Galactosemia
Authors: Peter Beate , Davis Jennifer , Cotter Sarah , Belter Alicia , Williams Emma , Stumpf Melissa , Bruce Laurel , Eng Linda , Kim Yookyung , Finestack Lizbeth , Stoel-Gammon Carol , Williams Delaney , Scherer Nancy , VanDam Mark , Potter Nancy
Published: October 2021

Purpose

Babble Boot Camp (BBC) is a package of proactive activities and routines designed to prevent speech and language disorders in infants at predictable risk. It is implemented via parent training and currently undergoing clinical trial in children with a newborn diagnosis of classic galactosemia (CG), a metabolic disease with high risk of speech and language disorders. The purpose of this study is to provide updates to a previous pilot study and to present the first set of post-intervention results.

Method

The intervention and data collection occurred during child ages < 6–24 months, with follow-up assessments of speech and language at ages 2.5 and 3.5 years. Treatment targets included earliest vocalization rates, babble complexity, speech production accuracy, and vocabulary and syntactic growth. The oldest 15 children with CG (including three untreated controls) completed the first set of follow-up assessments. Aggregate data up to 10 months were available for 17 treated children with CG, six untreated children with CG, and six typical controls.

Results

At ages 7–9 months, babbling complexity, as measured with mean babbling level, was higher in the treated children with CG than in the untreated children with CG and the typical controls. Prior to 24 months of age, the treated children with CG had greater expressive but not receptive vocabulary sizes than an untreated control. Follow-up testing showed typical language scores for all 12 treated children with CG and typical articulation scores for 11 of these, whereas one of three untreated children with CG had low articulation and expressive language scores.

Conclusions

The BBC appears to be a viable intervention to support the speech and expressive language development of children with GC. Future studies will evaluate the relative contributions of the earliest and later BBC components to outcomes.
Orbital obliquity sampling in the Kepler-20 system using the 3D animation software Blender
Authors: Müller H. M. , Ioannidis P. , Schmitt J. H. M. M.
Published: October 2021

Context.The mutual orbital alignment in multiple planetary systems is an important parameter for understanding their formation. There are a number of elaborate techniques to determine the alignment parameters using photometric or spectroscopic data. Planet–planet occultations (PPOs), which can occur in multiple transiting systems, are one intuitive example. While the presence of PPOs constrains the orbital alignment, the absence at first glance does not.

Aims.Planetary systems, for which the measurement of orbital obliquities with conventional techniques remains elusive, call for new methods whereby at least some information on the alignments can be obtained. Here we develop a method that uses photometric data to gain this kind of information from multi-transit events.

Methods.In our approach we synthesize multi-transit light curves of the exoplanets in question via the construction of a grid of projected orbital tilt anglesα, while keeping all transit parameters constant. These model light curves contain PPOs for some values ofα. To compute the model light curves, we use the 3D animation software Blender for our transit simulations, which allows the use of arbitrary surface brightness distributions of the star, such as limb darkening from model atmospheres. The resulting model light curves are then compared to actual measurements.

Results.We present a detailed study of the multi-transiting planetary system Kepler-20, including parameter fits of the transiting planets and an analysis of the stellar activity. We apply our method to Kepler-20 b and c, where we are able to exclude some orbital geometries, and find a tendency of these planets to eclipse in front of different stellar hemispheres in a prograde direction.

Conclusions.Despite the low statistical significance of our results in the case of Kepler-20, we argue that our method is valuable for systems where PPO signals larger than the noise can occur. According to our analysis, noise ≤ 2 × 10−4for planets like Kepler-20 b, or a planet radius ≥ 3REarthfor the smaller component and Kepler-20-like photometry, would be sufficient to achieve significant results.
X-ray spectroscopic survey of highly accreting AGN
Authors: Laurenti M. , Piconcelli E. , Zappacosta L. , Tombesi F. , Vignali C. , Bianchi S. , Marziani P. , Vagnetti F. , Bongiorno A. , Bischetti M. , del Olmo A. , Lanzuisi G. , Luminari A. , Middei R. , Perri M. , Ricci C. , Vietri G.
Published: October 2021

Improving our understanding of the nuclear properties of high-Eddington-ratio (λEdd) active galactic nuclei (AGN) is necessary since at this regime the radiation pressure is expected to affect the structure and efficiency of the accretion disc-corona system. This may cause departures from the typical nuclear properties of low-λEdd AGN, which have been largely studied so far. We present here the X-ray spectral analysis of 14 radio-quiet, λEdd ≳ 1 AGN at 0.4 ≤ z ≤ 0.75, observed with XMM-Newton. Optical/UV data from simultaneous Optical Monitor observations have also been considered. These quasars were selected to have relatively high values of black hole mass (MBH ∼ 108 − 8.5 M⊙) and bolometric luminosity (Lbol ∼ 1046 erg s−1) in order to complement previous studies of high-λEdd AGN at lower MBH and Lbol. We studied the relation between λEdd and other key X-ray spectral parameters, such as the photon index (Γ) of the power-law continuum, the X-ray bolometric correction (kbol, X), and the optical/UV-to-X-ray spectral index (αox). Our analysis reveals that, despite the homogeneous optical and supermassive black hole accretion properties, the X-ray properties of these high-λEdd AGN are quite heterogeneous. We indeed measured values of Γ between 1.3 and 2.5, at odds with the expectations based on previously reported Γ − λEdd relations, for which Γ ≥ 2 would be a ubiquitous hallmark of AGN with λEdd ∼ 1. Interestingly, we found that ∼30% of the sources are X-ray weak, with an X-ray emission about a factor of ∼10 − 80 fainter than that of typical AGN at similar UV luminosities. The X-ray weakness seems to be intrinsic and not due to the presence of absorption along the line of sight to the nucleus. This result may indicate that high-λEdd AGN commonly undergo periods of intrinsic X-ray weakness. Furthermore, results from follow-up monitoring with Swift of one of these X-ray weak sources suggest that these periods can last for several years.
Expanding one-zone model for blazar emission
Authors: Boula S. , Mastichiadis A.
Published: October 2021

Context. As a subcategory of active galactic nuclei, blazars are distinguished by their non-thermal variable emission. This emission extends over the whole electromagnetic spectrum and is a consequence of particle acceleration inside their relativistic jets. However, an open question remains regarding the relation of radio emission compared to that of higher frequencies.

Aims. Observations of blazar emission show that the location of radio might be very different from the one where the rest of the spectrum is produced and, thus, often requires separate modeling. We aim to produce both types of emission within the context of a single model.

Methods. We constructed a self-consistent one-zone expanding leptonic model for studying the connection between the radio emission and the emission at higher frequencies. We then applied it to the flaring states of blazars. Assuming an accelerating episode as the source moves down the jet and expands, we numerically studied the electron evolution as they lose energy due to adiabatic expansion and synchrotron or inverse Compton radiation.

Results. We find that high-frequency radiation mimics the electron injection and is mainly produced close to the acceleration site where cooling is strong. In contrast, the radio emission is produced further down the jet when the emitting region has become optically thin with regard to synchrotron self-absorption due to expansion. We briefly present the role of the initial parameters, such as the magnetic field strength, the electron luminosity, and expansion velocity, on the localization of the radio emission site. We show that the expanding one-zone model is inherently different from the non-expanding one and, in addition, it requires more parameters. For example, we apply our approach to the observational data of a Mrk 421 γ-ray and radio flare observed in 2013.
Philosophy of ecologized economics
Authors: Privalov Nikolay , Fursova Elena
Published: October 2021

The ecological crisis goes a long way back and has been brewing for centuries. The main factors of human alienation from nature: technical progress; suppression of pagan culture, that used to be tied to nature, world religions; spread of atheism; consolidation of the positivism paradigm in scientific methodology; triumph of the market economy model. As a result, humans were pulled out of their natural environment. They live and work by rhythms and rules contradicting natural laws. The result is the growing global crisis of industrial civilization.
Psychological factors of environmental responsibility of student youth
Authors: Mititsina Elena , Parfenova Nadezhda , Bizaeva Anna , Kovalevskaya Ekaterina , Guchkova Tatiana
Published: October 2021

The study addresses the current social problem of psychological determinants of environmentally responsible behavior. Environmental responsibility acts as a mediating link between the cognitive, values, and emotional components of ecological consciousness and the predisposition of young people to pro-ecological actions. The empirical material was collected using a questionnaire method followed by factor and cluster analysis. It was found that the motivation of environmental activity is most associated with the social and territorial identity of young people, in the least with the declared ecological values. Identity with interest groups determines the readiness to volunteer in environmental organizations. A sense of connection with large social communities increases the desire of young people for socio-political activity. Three equal in number groups of students were identified, who attribute responsibility for the natural environment to one of three factors: personal behavior, environmental organizations of various scales, as well as economic conditions, and state policy.
Infrastructure road construction environmental risks minimization
Authors: Sukhadolets Tatyana , Stupnikova Elena , Olenina Olga
Published: October 2021

Measures to reduce environmental risks within the infrastructure construction are mainly reduced to recommendations on use of renewable energy sources, and use of vehicles with hybrid and electric motors. The article shows that the predominant factor in reducing environmental risks is investment in fixed assets for environmental protection. The analysis performed using OLS confirmed that the degree of P-value dependence in all three constructed models was obtained for the Investments variable.
On the comprehensive indicator of the effectiveness of programs in the field of environmental safety and environmental development
Authors: Rybakov Anatoly , Ivanov Evgeniy , Kuzmin Alexander , Gorina Larisa
Published: October 2021

The paper offers a comprehensive indicator for evaluating the effectiveness of the implementation of state policy in the field of environmental safety and environmental development. The indicator under consideration can be a flexible tool for justifying the effectiveness of strategic planning measures in the field of environmental development, taking into account current development trends. The idea of solving the optimization problem (bringing the values of the complex indicator to the maximum) of forming a rational action plan for the implementation of state policy in the field of environmental safety and environmental development is proposed.
Ecological dimension of conflict in Nagorno-Karabakh
Authors: Basharov G. R. , Shedko F. S. , Okolota D. P. , Kotova A. L. , Volkova A. A.
Published: October 2021

This article examines the conflict in Nagorno-Karabakh not only from the point of the usual historical, ethnic and religious context, but also from the point of the environmental and resource dimensions, which are often ignored by researchers and practitioners of conflict resolution. The so called Six Weeks War significantly changed the current state of the conflict, and through focus group interviews and scientific analysis, the authors try to assess the impact of the environmental aspect on this conflict and substantiate its importance. The authors also hypothesize that the importance of environmental and resource factors is ignored by researchers and local residents, although these factors could become one of the foundations for building relationships, building trust and long-term conflict resolution.
Digital innovations as a development driver for regional management and consumer interaction in the post-pandemic period
Authors: Yampolskaya Diana , Chernikov Sergey U.
Published: October 2021

The development of enterprises and organizations in the new conditions created by the COVID-19 pandemic raises many problems and sets new challenges. This article examines issues related to the changing operating conditions of regional companies, their use of digital technologies and the development of e-commerce. The relevance of the work is dictated by extensive discussion of these issues in the media and field research to determine the readiness of companies to transition to digital technologies. The need for this transition is apparent. Both positive and negative aspects of the transition to new working conditions have been identified based on the results of a content analysis of open sources of information. Digital technologies enable more flexible and dynamic development of companies, comprehensive services to their customers through the creation of service ecosystems. Electronic commerce is developing rapidly. At the same time, digitalization can divide the team, increase control (and therefore pressure) on personnel, and cause emotional burnout of employees. Consideration of these areas and a set of digitalization tasks is the main topic of this publication.
“Green infrastructure” of urbanized territories
Authors: Maksimenko Ljubov , Dudinova Olga , Korobova Olga
Published: October 2021

Currently, there is a process of spatial concentration of the population and the spread of urban lifestyle, which inevitably leads to the expansion of the boundaries of cities and their sphere of influence, an increase in the diversity of activities. In this regard, the creation and maintenance of a comfortable urban environment of a megalopolis is becoming an increasingly urgent managerial task. The decisive factors in supporting urbanized territories in a comfortable state for living are the objects of” green “ infrastructure. One of the important issues, at the same time, is the information support of the management system for the territories of land plots with green spaces.
Improving energy efficiency through the use of waste heat products in the production of building materials
Authors: Medvedeva Galina , Giniyatova Kamilla , Minikaeva Kamilia
Published: October 2021

Concern for the sustainable management and recycling of solid waste is becoming more visible in all sectors of the economy. This study explores the possibility of using coal ash residue (waste from Kazan CHPP-2) as a substitute for fine-grained aggregate in sulfur concrete. The trend towards an increase in the level of utilization of waste heat power engineering is an important task. The chemical composition, microstructure and mechanical properties, including density, water absorption, compressive strength and thermal conductivity of sulfur concrete, including coal ash with partial and complete sand replacement, were investigated and the results were compared with those for standard cellular concrete. The authors studied modern heat-insulating materials and materials from industrial waste products. The article analyzes the estimated thickness of the insulating material depending on the type of structure. Outside walls made of sulfur concrete, in addition to high strength properties, have high thermal and economic performance.
Labor intensity in context of information and communication technologies sustainable development
Authors: Krasova Elena
Published: October 2021

The information and communication technologies (ICT) impact on labor intensity is one of the actual, but understudied interdisciplinary issues of modern science and practice. Observations and analysis of labor processes in context of the ICT use point out the increase in labor intensity. The purpose of the research is to identify key sources of workers’ labor intensity growth under the ICT development, regardless of the field of professional activity. The article highlights such sources as increase in work strenuousness, growth of number of labor functions and operations, lengthening working day, and also change in work and rest regime. A special focus is on the problem of «leisure time colonization». An ∩-shaped correlation between labor intensity and productivity is presented. The general conclusion that unlimited growth of labor intensity is inconsistent with the sustainable development and effective development of human capital is made.
Labour market under economy digitalization
Authors: Kenzhin Z. B. , Tulegenova A.U. , Zolkin A. L. , Kosnikova O. V. , Shichkin I.A.
Published: October 2021

The main problems of current labour market under economy digitalization caused by COVID-19 pandemic are reviewed in this article. Current economy system is based on factors of innovative development that effects on labour market and, therewith, reducing employment of population and increasing of structural unemployment. Therefore, the problems of labour market studies are becoming actual according to structural development of economy system itself in the age of economy globalization. Methodological framework has defined against the background of developed procedures and regulatory settings for regulation of labour market and labour power in Kazakhstan. The assessment, composition and statistical analysis methods were used for studies.
Sociocultural anthropoecology as an element of human resources management policy in the context of sustainable development
Authors: Kruglova Larisa Konstantinovna
Published: October 2021

The article examines the heuristic and methodological potential of socio-cultural anthropoecology as an element of human resources management policy in the context of sustainable development. The author defines socio-cultural anthropology ecology as the science of the laws of structure, functioning and development of the ecosystem “man - nature - society - culture”. The article shows that the development of socio-cultural anthropoecology as a scientific discipline makes it possible to get new knowledge in such spheres as general principles of human interaction with the living environment and its individual components; favorable and unfavorable living conditions (natural, social, cultural) typology of personality, the criterion of which construction is the nature of the interaction of the individual with the environment of life. The article concludes that the institutionalization of socio-cultural anthropoecology and its development as a scientific and educational discipline are necessary for strengthen of theoretical base and increasing of effectiveness of human resource management policy in the context of sustainable development