bluuebunny/crossref_metadata_2025 huggingface dataset:
Papel del contexto urbano en la relación entre los síntomas ansiosos y el trastorno del espectro del autismo
Authors: Sáez Suanes Gema P. , García-Villamisar Domingo , Del Pozo Armentia Araceli
Published: September 2023

Diversas investigaciones demostraron una notable prevalencia de la sintomatología ansiosa comórbida en personas afectadas por un trastorno del espectro del autismo (TEA). Esta prevalencia es muy superior a la que se observa en población normotípica. Esta investigación tiene por objetivo esclarecer si el contexto modera esta asociación entre ansiedad y autismo. En este estudio participaron ciento veintiún adultos (M = 35.46 años¸ SD = 9.46) con TEA y discapacidad intelectual (DI). Se realizó un análisis de moderación para conocer el papel del contexto – rural o urbano – en el desarrollo de síntomas ansiosos en personas con TEA. Los resultados alcanzados permiten concluir que el contexto urbano moderó de forma significativa la relación entre el TEA y los síntomas ansiosos. Estos resultados sugieren implicaciones para prevenir o reducir los síntomas ansiosos en las personas con TEA y DI relacionadas con las características del contexto en el que se desarrollan.
Role of DNA Repair Pathways in Response to Zidovudine-induced DNA Damage in Immortalized Human Liver THLE2 Cells
Authors:   Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA, Fang Jia-Long , Beland Frederick A. ,   Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA, Chang Ching-Wei ,   Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA, Wu Qiangen ,   Department of Environmental Health, Indiana University, Bloomington, IN 47405, USA
Published: September 2023

The nucleoside reverse transcriptase inhibitor zidovudine (3'-azido-3'-dexoythymidine, AZT) can be incorporated into DNA and cause DNA damage. Previously, we determined that the human hepatocellular carcinoma HepG2 cells are more susceptible to AZT-induced toxicities than the immortalized normal human liver THLE2 cells and the nucleotide excision repair (NER) pathway plays an essential role in the response to AZT-induced DNA damage. We have now investigated if the effects of AZT treatment on the expression levels of genes related to DNA damage and repair pathways contribute to the differences in sensitivity to AZT treatment between HepG2 cells and THLE2 cells. Of total 84 genes related to DNA damage and repair, two, five, and six genes were up-regulated more than 1.5-fold at 50, 500, and 2,500 µM AZT groups compared with that of control THLE2 cells. Seven genes showed a decreased expression of more than 1.5-fold following the 2,500 µM AZT treatment. Two-sided multivariate analysis of variance indicated that the change in expression of genes involved in apoptosis, cell cycle, and DNA repair pathways was significant only at 2,500 µM AZT. Statistically significant dose-related increases were identified in XPC gene expression and GTF2H1 protein level after the AZT treatments, which implicated the NER pathway in response to the DNA damage induced by AZT. In contrast, AZT treatment did not alter significantly the expression of the APE1 gene or the levels of APE1 protein. These results indicate that the NER repair pathway is involved in AZT-induced DNA damage response in immortalized human hepatic THLE2 cells.
The Ethnobotanical, Phytochemical and Mineral Analyses of Phragmanthera Incana (Klotzsch), A Species of Mistletoe Growing on Three Plant Hosts in South-Western Nigeria
Authors:   Department of Biological Sciences, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria, Ogunmefun O. T. , Fasola T. R. ,   Department of Botany, Faculty of Science, University of Ibadan, Ibadan, Nigeria, Saba A. B. , Oridupa O. A. ,   Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria
Published: September 2023

Mistletoe is collected wildly on various plants and Phragmanthera incana is noted to grow on different plant hosts. This study was designed to carry out the ethnobotanical survey, phytochemical and mineral analyses of Phragmanthera incana, a species of mistletoe growing on three plant hosts namely Cocoa (Theobroma cacao), Kolanut (Cola nitida) and Bush mango (Irvingia gabonensis). Mistletoe samples were identified at the Forestry Research Institute of Nigeria Herbarium. Phragmanthera incana was screened for its phytochemical constituents and mineral cations along its hosts following standard methods and to confirm if the mistletoe species is host specific. The powdered samples of the mistletoe species (Phragmanthera incana) was used for both the phytochemical screening and the cation mineral analysis. The uses and the harvesting methods of mistletoe were also reviewed extensively in this paper.
Predictive Value of Pretreatment BCR-ABLIS Transcript level on Response to Imatinib Therapy in Egyptian Patients with Chronic Phase Chronic Myeloid Leukemia (CPCML)
Authors:   Clinical Oncology Center, School of Medicine, Cairo University, Egypt, El-Metnawy Wafaa H. , Mattar Mervat M. , Abdelhamid Hala M. ,   Department of Hematology, School of Medicine, Cairo University, Egypt, El-Nahass Yasser H. ,   Department of Clinical Pathology, National Cancer Institute, Cairo University, Egypt, Samra Mohamed A. , AbdlFattah Raafat M. ,   Department of Medical Oncology, National Cancer Institute, Cairo University, Egypt, Hamed Ahmad R. ,   Pharmaceutical Research Group, National Research Center, Cairo, Egypt
Published: September 2023

Background: A wide range of responses of patients with CPCML to IM has been reported. Several factors were proposed to predict response including molecular response at 3 and 6 months. Purpose: To study the impact of pretreatment BCR-ABL transcript level on molecular response to IM, and to assess the value of the milestone; ≤10% transcript at 3 months on PFS and OS. Patients and Methods:Fifty five adult CP-CML patients receiving daily dose of 400 mg IM were subjected to molecular and cytogenetic analysis at diagnosis and at regular time intervals. Median follow up period was 36 months (15-48). Hematologic, cytogenetic, and molecular responses were rated according to ELN. Results: Two Patient groups were distinguished regarding response to IM therapy. A group of 22/55 patients (40%) having pretreatment BCR-ABLIS level ≤200% and a second patient group 33/55 (60%) having transcript level >200%. The ≤10% milestone was achieved by 15/22 patients (68%) versus 7/33 patients (21%), p=0.04 in favor of the first group. Optimal responders in first group were 14/22 (64%) compared to 13/33 (39%) in second group, p=0.02. Achievement of 10% transcript level significantly correlated with longer PFS. The median BCR-ABLIS transcripts levels in optimal responders at 3, 6 and 18 months was 10%, 2% and 0.1%, respectively compared to 100%, 65% and 10%, in suboptimal/resistant patients p=0.001. Resistance in 11 patients was correlated with identifiable ABL Kinase mutations. Conclusion: The Pretreatment 200% cutoff and the 3 month BCR-ABLIS ≤10% transcript levels proved strong predictors of response to IM and significantly correlated with probability of CCyR, MMR and PFS.
Inhibitory Effect of Phenolic Extract from Garlic on Angiotensin-1 Converting Enzyme and Cisplatin induced Lipid Peroxidation - In Vitro
Authors:   Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria, P.M.B. 704, Akure 340001, Nigeria, oboh Ganiyu , Ademiluyi Adedayo O. ,   Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, Akure, Nigeria, P.M.B. 704, Akure 340001, Nigeria, Akinyemi Ayodele J. ,   Department of Biochemistry, Afe Babalola University, Ado-Ekiti, Nigeria, P.M.B. 5454, Nigeria
Published: September 2023

Allium sativum have been an important food ingredient in the management or treatment of renal disease. Therefore, this study sought to determine the inhibitory effect of phenolic-rich extract from A. sativum on angiotensin 1 converting enzyme (ACE) activity (key enzyme linked to renal dysfunction) and cisplatin-induced lipid peroxidation in rat kidney in vitro. The free phenolics were extracted with 80% acetone, while the bound phenolics were extracted from the alkaline and acid hydrolyzed residue with ethyl acetate. Thereafter, their inhibitory effect on angiotensin 1 converting enzyme (ACE) activity and cisplatin-induced lipid peroxidation in rat kidney were determined-in vitro. The results revealed that the free phenolics had significantly higher (P<0.05) inhibitory effect on ACE activity than the bound phenolics. Furthermore, incubation of rat kidney in presence of 1 mM cisplatin caused a significant increase (P<0.05) in the malondialdehyde (MDA) content, however, both extracts inhibited MDA produced in a dose dependent manner. The additive and/or synergistic action of the free and bound phenolics could have contributed to the observed medicinal properties of the spice. Therefore, inhibition of ACE activity and prevention of oxidative stress in the kidney could be some of the possible mechanism by which they exert nephroprotective properties. However, the bound phenolic extracts showed stronger inhibition on ACE activity in vitro.
Conservative Treatment in Early Cervical Cancer
Authors:   Associate Prof, Gynecologist Oncologist, Shahid Sadoughi University of Medical Science, Yazd, Iran, Karimi-Zarchi Mojgan , Mousavi Azamsadat , Gilani Mitra Modares ,   Prof, Gynecologist Oncologist, Tehran University of Medical Science, Tehran, Iran, Barooti Esmat ,   Associate Prof, Functional Gynecology, Taleghani Hospital, Velenjak Avenue, Tehran, Iran, Miratashi-Yazdi Ashrafosadat ,   Assistant Prof, Internal medicine, Yazd Branch, Islamic Azad University, Yazd , Iran, Dehghani Atefe ,   M.D, Shahid Sadoughi University of Medical Science, Yazd, Iran
Published: September 2023

Purpose of review: The aim of this study was to describe fertility preservation methods to improve quality of life of early stages of cervical cancer. Recent finding: Although definite treatment of early stages of cervical cancer including stages IA,IB1 and IIA non-bulky is radial hysterectomy, this method is used in perimenopousal period in which fertility preservation is not important. Whenever fertility preservation is so important, some methods like radical trachelectomy and laparoscopic lymphadenectomy are used to rule out lymphatic metastases. Summary: If any visible lesion on cervix is found, pelvic MRI is helpful and during operation, trachelectomy samples are sent for frozen section and margin study. Radical trachelectomy is done vaginal or abdominal. Overall relapse rate of cervical cancer in radical trachelectomy and radical hysterectomy is the same. Complications of radical trachelectomy include chronic vaginal discharge, abnormal uterine bleeding, dysmenorrhea, inflammation and ulcer due to cercelage, amenorrhea, cervical stenosis and pregnancy complications following trachelectomy including 2nd trimester abortion and premature labor following cervical prematurity.The best and preferred method of labor is cesarean section. Neoadjuant chemotherapy followed by radical trachelectomy in large cervical lesions is a suitable treatment. Ultraconservative operations like large cold knife conization, simple trachelectomy with laparoscopic lymphadenectomy and sentinel lymph node mapping are suitable for very small lesions.
Development of Stability-Indicating Methods for Cefquinome Sulphate
Authors:   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Sudan, Shantier Shaza W. , Gadkariem Elrasheed A. , Adam Mohamed O. , Mohamed Magdi A.
Published: September 2023

The degradation behavior of cefquinome sulphate in alkaline medium at different temperatures was investigated using both first derivative spectrophotometric and HPLC methods. The drug degradation was found to be pH and temperature dependant. The pH-rate profile indicated a first order dependence of Kobs on [OH-] at pHs ranging between 9 and 11. Arrhenius plot obtained at pH 10 was linear between 65° and 100°C. The estimated activation energy of the hydrolysis was found to be 21.1 kcal mol-1. Stability-indicating thin-layer chromatographic method for the separation of the drug and its alkaline hydrolysis product has been developed.
Seroepidemiology of Helicobacter Pylori Infection in Pregnant Women in Rural Durango, Mexico
Authors:   Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Juarez University of Durango State, Avenida Universidad S/N. 34000 Durango, Dgo, Mexico, Alvarado-Esquivel Cosme
Published: September 2023

The seroepidemiology of Helicobacter pylori infection in pregnant women in Durango, Mexico is largely unknown. The prevalence of anti-H. pylori IgG antibodies was examined in 343 pregnant women living in rural areas in 7 municipalities in Durango State, Mexico, using enzyme-linked immunosorbent assays (ELISA). A correlation of H. pylori seropositivity with socio-demographic, obstetric and behavioral characteristics of pregnant women was also assessed. In total, 179 (52.2%) of the 343 pregnant women (mean age, 24.2 ± 5.9 years) had H. pylori IgG antibodies, 75 (41.9%) of whom had H. pylori IgG antibody levels higher than 100 U/mL. The seroprevalence of H. pylori infection varied from 33.3% to 65% among municipalities. In contrast, the seroprevalence was comparable among women regardless their age, educational level, occupation, socioeconomic status, animal contacts, foreign travel, eating habits, contact with soil, crowding, sanitary conditions at home and educational level of the head of their families. Multivariant analysis of socio-demographic and behavioral variables showed that H. pylori seropositivity was associated with municipality (OR=1.12; 95% CI: 1.01–1.24; P=0.02). Of the obstetric characteristics, the seroprevalence of H. pylori infection increased significantly with the number of pregnancies and deliveries but not with the number of cesarean sections or miscarriages. Rural pregnant women in Durango had a lower seroprevalence of H. pylori infection than those from populations in developing countries. Results support a variability of H. pylori seroprevalence within a region. Further research at a municipal level might help to understand the epidemiology of H. pylori infection.
Presentation of Preauricular Sinus and Preauricular Sinus Abscess in Southwest Nigeria
Authors:   Department of ENT, University of Ilorin teaching hospital, Nigeria, Alabi B. S. , Nwawolo C. C. ,   Department of ENT, Lagos University teaching hospital, Lagos, Nigeria, Adegbiji W. A. , Olajuyin O. A. ,   Department of ENT, University of Ado-Ekiti teaching hospital, Nigeria
Published: September 2023

Background and Aim: Preauricular sinus abscess is a common congenital external ear disease. This abscess is usually misdiagnosed because it is commonly overlooked during physical examination. In Nigeria, the prevalence was 9.3% in Ilorin, north central Nigeria This study is to determine the distribution and clinical presentation of the preauricular sinus abscess in Ekiti, south west Nigeria. MATERIALS and methods: This is a prospective hospital based study of all patients with diagnosis of preauricular sinus abscess seen in our clinic carried out between April 2008 to March 2010. Detailed clinical history, administered interviewer's assisted questionnaires full examination and. Data obtained were collated and analysed. RESULTS: Preauricular sinus were noticed in 184 (4.4%) out of 4170 patients seen during the study period. Preauricular sinus abscess were noticed in 21 (11.4%) of the preauricular sinuses especially in children. Unilateral preauricular sinus abscess accounted for 90.5%. Common presenting complaints were preauricular swelling (81.0%), 90.5% with recurrent earaches, 76.2% with ear discharges. All patients had antibiotic / analgesic while 17 out of 21 (81.0%) had surgical excisions. CONCLUSION: Preauricular sinus abscess were noticed among 11.4% of the preauricular sinuses especially in children, unilateral preauricular sinus abscess accounted for 90.5%. Common complaints were otorrhoea, earaches, and swelling and they were mostly managed surgically.
Synergize Business With Artificial Intelligence
Authors:   Principal, Government Arts and Science College, Avinashi-641654, Tirupur Dt. Tamil Nadu, India., J. Nalatham
Published: September 2023

Synergize Business With Artificial Intelligence Author: Dr. J. Nalatham, Principal, Government Arts and Science College, Avinashi-641654, Tirupur Dt. Tamil Nadu, India. DOI: https://doi.org/10.59646/synergizebusiness/044 ISBN: 978-81-965552-5-2 Date of Publication: September 19, 2023 About the Book: Artificial intelligence presents both the greatest potential and the greatest danger to small enterprises in the modern era. Now more than ever, artificial intelligence technologies are within reach of even the smallest of organisations. There is a significant influx of new low-cost AI apps reaching the market, and these tools may assist small businesses in swiftly expanding their earnings. These newly developed AI tools are simple to implement, do not call for specialised expertise such as that of software engineers or data scientists, and may be realised using no-code or low-code solutions. The author of this book breaks down the cognitive process into easy stages that the reader may instantly put into practise. You will find more deep methods to apply AI as you develop and expand, which will drive your new growth in a manner that has never been possible before.
"Nordeste é uma ficção. Nordeste nunca houve": o migrante nordestino e a experiência da diáspora nas canções de Belchior
Authors: Caviola André Luiz Rocha Mattos
Published: September 2023

O objetivo desse artigo é explorar a narrativa do migrante nordestino nas canções de Antônio Carlos Belchior e como a perspectiva diaspórica da trajetória do artista expressa-se de maneira sensível na sua forma de criar e representar o mundo enquanto sujeito migrante. Para isso, serão analisadas as canções Passeio (1974), Fotografia 3x4 (1976) e Conheço o Meu Lugar (1979), a partir de uma apreensão empírica da canção (TATIT, 2003) e de uma interpretação balizada na perspectiva de uma antropologia literária (ISER, 2013).
A pedra de uma tonelada: como o rock ‘n’ roll ficou pesado
Authors: Passos Leonardo Porto , Falleiros Manuel Silveira
Published: September 2023

O presente artigo apresenta pesquisa bibliográfica, dentro do campo de estudo de gêneros musicais, acerca do desenvolvimento do que convencionou-se chamar de som “pesado” (heaviness) ao longo de aproximadamente sete décadas da história do rock. Embora em sua origem essa característica da estética sonora ainda não fosse determinante, o artigo mostra como ela foi se evidenciando progressivamente com o passar do tempo, tornando-se uma preocupação constante de muitos músicos e até mesmo uma característica definidora de diversos subgêneros do rock.
The Concept Of Legal Regulation Of Soe Restructuring Through Holding Mechanism
Authors: Kartiadi Prasetyo , Kusbianto Kusbianto , Sahputra Rilawadi
Published: September 2023

Given the contribution of state-owned enterprises that need to be increased enough, to improve and empower massively several sectors in the state-owned companies, restructuring must be accommodated. Thus, the restructuring of state-owned enterprises with formation of holding companies for each sector has been planned by the government, which is the Ministry of SOEs. The purpose of the initial idea of restructuring and establishing a state-owned holding company is to optimize its management. However, while its main objective is to gradually intensify its management and profitability, the government plans to restructuring SOEs must face several obstacles, one of which is related to anti-competitive law. In an Operating Holding Company, the parent company carries out business activities and controls subsidiaries. The form of Operating Holding Company run by PTPN III (Persero) as the parent company is not only to carry out its business activities but also control and supervise subsidiaries.
Structuralization and comparison of electoral formulas for the election of collegial representative bodies of local government in the Visegrad Group countries (as of 2018)
Authors: Cholovska Oleksandra
Published: September 2023

The notion of an electoral system has a broad meaning and includes a number of elements. Among them are an electoral formula, the number of mandates for a constituency, an electoral threshold, a structure of the ballot, an effective number of parties, an electoral variability, indicators of proportionality or disproportionality, attractiveness and substitution of electoral systems. At the same time, the article focuses on the concept of an electoral formula. Since it analyzes the electoral formulas used at local elections in the countries of the Visegrad Group. In particular, the author, in the context of comparing the electoral formulas, took into account such criteria as the ways of distribution of deputy mandates, the size/magnitude of electoral districts, the electoral threshold and the structure of the ballot.As a result, the researcher analyzed the electoral formulas for the election of collegial representative bodies of local government in the countries of the Visegrad Group.
Corruption counteraction by the civil society: comparative analysis of the experience of Romania, Hungary and Poland
Authors: Kabantseva Iryna
Published: September 2023

The article examines the evolution of the civil society in Romania, Hungary, and Poland. A projection is made on one of the spheres of the “third sector” activity – prevention of corruption in politics and other spheres. The author analyzes the experience of the civil society of each of the countries regarding the supervision of policy makers in terms of their compliance with the requirements of transparent activity, prevention of conflicts of interest, and prevention of different manifestations of informal institutionalization. The study focuses on the peculiarities of the forms of corruption counteraction by the civil society in Romania, Hungary, and Poland, and identifies the obstacles that hinder the anticorruption activity of the civil society actors.
Claim as a means of protection of rights, freedoms and interests
Authors: Butyrskaya Iryna A.
Published: September 2023

The article deals with the concept and features of the claim. The existing approaches in the legal science to the definition of “claim” are analyzed. The correlation between the claim and the statement of claim is disclosed. Characteristic features of the claim are established. The classification of claims according to different criteria is carried out. The author comes to the conclusion that the claim is expressed in the statement of claim and appealed to the court re- quest of the plaintiff to provide him with state assistance in the implementation of his violated or disputed rights, freedoms and interests.
The Social and Economic Problems of Cross-border Affairs in Central and East Europe: Case Study of the Polish-Ukrainian Cooperation
Authors:   Akademia Nauk Stosowanych Gospodarki Krajowej, Hrabynskyy Ihor
Published: September 2023

The development of cross-border cooperation is an effective factor in overcoming of the social and economic problems caused by the presence of the Polish-Ukrainian border. Regardless of the level of economic development, the border areas and frontier territories of any state remain at the periphery of its economic priorities. Business tends to the capital, large economic and logistic centers, while in the peripheral regions, the structure of the economy is objectively deformed with depressive trends, which is the result of objective processes in a competitive market economy. The Polish-Ukrainian border has a number of specific features that are not inherent in other regions. Existing borders were formed only in the middle of the 20th century and cross-border cooperation aimed at preserving and restoring Ukrainian and Polish cultural heritage and supporting the development of transboundary economic forms would help to overcome the existing problems of the border areas.
Populism as a theoretical framework: modern aspect for political system
Authors: Kiyanka Iryna
Published: September 2023

In the article considered the common and special approach in different European countries to the definition of populism, traced the evolution of the concept from the ancient period. Thus, we can state that the concept of populism is a multifaceted political construct that performs the integrative-cognitive function of structuring and constructing a complex and controversial political reality with elements of social, discursive and praxeological eclecticism. A characteristic feature of the actualization of populism is the extreme parameters of the functioning of the state-political organism of society and the value projections of its existence. The crisis of society, which generates a conceptual platform of populism, reflects the objective need for democratization of the foundations of social order and social life. In particular, the anti-elite orientation of populism is due to the need to expand the influence of the subject field and instruments of direct democracy and direct democracy. The anthropological optimism of populism contrasts with the static-consensual metaphysics of the elitis.
Emotion Dysregulation Linked to Depression Symptoms in a Sub-Saharan Sample of Adolescent University Students
Authors: Nderitu Bernice , Kihara Michael , Basnight-Brown Dana
Published: September 2023

Emotions are fundamental to human development and survival across the lifespan. Adolescence is a volatile and critical developmental period characterized by frequent high-intensity positive and negative emotions. Emotion dysregulation and depression symptoms are common occurrences in adolescence. This study explored the association between emotion regulation difficulties and depressive symptoms in adolescents. The study was anchored on the extended process model of emotion regulation. The study employed a descriptive-analytical design and sampled 352 adolescents, ages 18-19, from the United States International University-Africa, Kenya. SPSS® v28 was used to analyze data and apply descriptive and inferential statistics. The study found no gender or ethnic differences in emotion regulation. However, there was a significant association between emotion regulation difficulties and depression, χ2 (3) = 12.133, p = 0.007, V = 0.186, and a positive and significant linear relationship between the variables, r (352) = 0.229, p < 0.001, r2 = 0.052. Notably, the higher the emotion regulation difficulties, the higher the depression levels. The study concluded that emotionally dysregulated adolescent university students are particularly vulnerable to developing psychological symptoms of depression.
Implication of Renewable Heat Policy on Reducing Carbon Emissions in China: A Dynamic CGE Simulation
Authors: Xiong Chengcheng , Hassan Mohd Sayuti
Published: September 2023

In 2020, China pledged to achieve carbon emission peaking before 2030 and carbon emission neutrality before 2060. Renewable heat is a key solution for decarbonizing the heating sector, which is responsible for more than 40% of global CO2 emissions. Policy interventions are necessary for scaling up renewable heat deployment due to both economic and non-economic barriers faced, while the instrument selection should be taken into account carefully. Thus, a dynamic computable general equilibrium (CGE) model was built to evaluate and compare the effects with different renewable heat policy shocks. The scenario analysis method is applied to compare two types of policies relative to baseline scenarios, subsidy, and energy tax. The findings indicate that: first, both subsidy and energy tax have positive effects on CO2 emission reductions while economic factors should also be accounted for. Secondly, the selection of subsidy and energy tax should seek a balance between economic factors and environmental factors as they may also affect economic growth or sectoral output to some degree. The energy tax rate should be moderate to avoid high economic impact. Thirdly, energy tax levying in the medium-long term has a beneficial impact on GHG emissions, while the instruments should be adopted with a careful rate chosen to avoid unnecessary tax burden on sectors that impede the orderly transition of relevant industries. Fourthly, it's reasonable to set a relatively high subsidy rate in the initial stage and gradually reduce the intensity of the renewable heating subsidy rate. For the energy tax rate, it is necessary to connect with the carbon trading market to set a relatively reasonable rate-setting mechanism to meet the dynamic needs of different stages.
Unveiling the Dynamics of the Omicron Variant: Prevalence, Risk Factors, and Vaccination Efficacy during the Third Wave of Covid-19 in Indonesia's Gowa Regency
Authors: Amiruddin Ridwan , Dwinata Indra , Ayu Rosa Devitha , Jafar Nurhaedar , Gaffar Gaffar , Kasim Syaharuddin , Kasim Muh Firdaus , Syarifah Adriana
Published: September 2023

Introduction: In February-March 2022, the B.1.1.529 (Omicron) variant of SARS-CoV-2 became the cause of the third wave of COVID-19 in Indonesia. However, data on the prevalence of the effects of the third wave of the COVID-19 pandemic are still limited, especially in regencies/cities in Indonesia. Gowa Regency is one of the most affected areas by COVID-19 in South Sulawesi.

Objective: Ascertaining risk factors associated with infection and evaluating the effectiveness of vaccination programs in Gowa Regency.

Methods: In March 2022, venous blood specimens were taken from 859 randomly selected samples in Gowa Regency to determine the presence of antibodies to SARS-CoV-2 by examining chemiluminescent microparticle immunoassay (CMIA) specimens. Information on demographics, previous infection history, symptoms, comorbid diseases, and vacancy status was collected through interviews. Data analysis was conducted using descriptive, bivariate tests with chi-square and One-way ANOVA, and multivariate tests using logistic regression.

Results: The overall prevalence of anti-SARS-CoV-2-IgG was 98.7%. The results showed that the prevalence of SARS-CoV-2 antibodies was not significantly different in terms of sex (P=0.306), age group (P=0.190), education (P=0.749), and occupation (P=0.685), history of COVID-19 symptoms (P=0.108), history of confirmation of COVID-19 (P=0.352), and history of comorbid diseases (P=0.477). However, this study showed that the prevalence of SARS-CoV-2 antibodies differed significantly among the fully vaccinated and incomplete groups (P <0.001).

Conclusion: There was a significant difference between the antibody status of respondents who had been fully vaccinated (at least two doses) and respondents who had not completed the vaccination.
Performance of crossbred dairy cattle under commercial farming conditions in the Chattogram district, Bangladesh
Authors: Adhikary Kona , Roy Kamol , Barua Karabi , Akter Nasima , Bhowmik Priunka , Sultan Nahid , Emran Hossain Md.
Published: September 2023

The study was conducted in 10 different farms under 6 upazilas, i.e., Hathazari, Patiya, Anwara, Boalkhali, Bakalia and Patenga of Chattogram district. The records of 50 crossbred dairy cattle (CDC) were collected for two crossbred dairy breeds, i.e., Holstein Friesian × Jersey (HF × J) and Holstein Friesian × Local (HF × L) from March to June 2019. Farms having ≥50 CDC with complete records of each cattle were selected for the study purpose. Results indicated that the genotype, supply of green roughage and concentrate, and feeding of CDC immediate before milking had significant (p<0.001) positive linear effect on average daily milk yield (ADMY). Supply of green roughage and concentrate had further positive quadratic and cubic effects (p<0.001) on ADMY. Postpartum period quadratically influenced the ADMY (p<0.05) although linear and cubic effects were nil (p>0.05). Parity and genotype had significant (p<0.05) positive effect on lactation period of the CDC. Among the HF × J crossbreds, 75%+25% genotypes resulted in greater milk yield than the others. Similarly, the 87.5% + 12.5% HF × L produced more milk than the other genotypes. However, the farm type, housing systems, grass type, milking system, parity, service per conception, lactation period, age at puberty, age at first calving, and the dry period had no effect (p>0.05) on ADMY in the CDC. Overall, HF × J performed better than the HF × L. It was concluded that both HF × J and HF × L crossbreds were well adapted under medium-scale commercial farming conditions of Bangladesh.
Prevalence of dog bite in animals, and humans’ perception of rabies in southeastern part of Bangladesh: a veterinary public concern
Authors: Das Tridip , Ahmed Rana Eaftekhar , Rahman Mizanur , Bayazid Bostami Mohammad , Md. Rakib Tofazzal , Inkeyas Uddin Mohammad , Das Shubhagata , Rashedul Alam Mohammad
Published: September 2023

Dog bite is one of the most common and significant predisposing factors for transmission of rabies from reservoir to other hosts including human. Human perception about infectious diseases like rabies is arguably the most deciding factor in controlling epidemics. A cross sectional study was conducted on dog bite cases in domestic and pet animals of 17veterinary hospital entrants in southeastern part of Bangladesh from January to December 2018 and the respondent perception regarding rabies, dog bite management and post exposure vaccination (PEV) information was also collected by using a pre-structured questionnaire. All the dog bite cases were confirmed based on patient history, clinical signs and physical examination. Finally, all data were summarized using Stata 13 programme. A total of 895 dog bite cases (11.9%; 95% CI 11.1-12.6) were confirmed from 7538 outpatients. Of them, highest prevalence was found in dog (33.3%; 95% CI23.3-45.1) followed by goat (12.6%; 95% CI 12.1-13.8) and cattle (6.9%, 95% CI 5.7-8.2). Among the body sites, thigh region was found to be the most vulnerable region for dog bite (50 to 73.9%) in all species. However, female (13.3%) and younger (11.6%) animals were frequently affected by dog bite in all cases. Out of 327 respondents, about 59% animal owners had preliminary knowledge about rabies and they were concerned about fatality and consequences of this disease. Perception regarding post exposure vaccination (PEV) was quite variable among dog owners (65.8%) and farmers (34.2%), where most farmers (82.9%) perceived that government veterinary hospitals are the only center for PEVs. This study reveals a high proportion of dog bite patients in veterinary hospitals in Bangladesh and the majority of animal owners do not have appropriate perception on post exposure prophylaxis (PEP) in dog bite cases.
Evaluation of bilateral tibial fracture management by external and internal fixation technique in a calf
Authors: Chandra Das Bhajan , Tasnim Brist Sabiha Zarin , Kumar Yadav Saroj , Chandra Sutradhar Bibek
Published: September 2023

Unilateral diaphyseal tibial fractures are very common in different species of animals but the occurrence and repair of bilateral diaphyseal tibial fractures are very rare. The aim of the present study is to evaluate the efficacy of bilateral tibial fracture management in a calf. The study was performed in a 75 days old cross-bred calf weighing 42 kgs which was suffering from bilateral tibial fracture and treated by external coaptation technique on left tibia and internal fixation by retrograde intramedullary pinning on the right tibia. The patient was evaluated after treatment at different intervals by recording the lameness grade, functional limb outcome, fracture healing. Satisfactory posture (weight bearing), gait and secondary bone healing in both left and right tibia were noticed up to 93 day of post-treatment with the minor complications of swelling and stiffness of the right hock joint and hyperextension of fetlock joint of left hind limb. This technique can be used in bilateral tibial fracture management in calf in field condition with reasonable cost
Surgical management of preputial prolapse in a bull- a case report
Authors: Chandra Sutradhar Bibek , Tasnim Bristi, Sabiha Zarin , Biswas Sreekanta , Chowdhury Joya
Published: September 2023

A 3-year-old male 400kg cross-breed bull was referred to the ambulatory service of Shahedul Alam Quadary Teaching Veterinary Hospital, Chattogram Veterinary and Animal Sciences University (CVASU) with the history of wound and laceration of the preputial region. Physical examination revealed oedema, laceration and necrosis of tissue at the prolapsed preputial sheath. Surgical removal of the affected part of the prepuce was considered as the treatment option. Standing sedation was achieved by injecting xylazine intravenously and 2% lidocaine infiltrated at the site of the incision. Following standing sedation, the affected portion of the prepuce was amputated and sutured. A polyvinyl chloride plastic pipe (PVC pipe) was placed at the preputial orifice to facilitate urination and wound healing. After placing the tube, a pressure bandage was given to stabilize the tube in the preputial orifice. In addition, antibiotic, antihistaminic and Nonsteroidal anti-inflammatory drug were prescribed. The pressure bandage and PVC pipe were removed after 3 days and dressing of the affected area by povidone-iodine was suggested. The bull was completely recovered within 21 days of treatment. The study indicated a cost-effective and simple surgical intervention to treat preputial prolapsed in bull with minium complications and postoperative care.
Correlation Study between Debt-Equity Ratio and Asset Returns with Relative Market Value to Book Value in the Indonesian Mining Industry (2020-2022)
Authors: Rahman Moch Ridho Ghazali
Published: September 2023

This research aims to analyze the influence of Debt to Equity Ratio and Return on Asset on Price to Book Value within the Indonesian mining industry for the years 2020-2022. Utilizing a quantitative methodology and an associative approach, the study was carried out from April to June 2023. From a population of 80 mining companies listed on the Indonesia Stock Exchange, 25 were selected as samples through purposive sampling Findings suggest that the Debt to Equity Ratio does not significantly impact Price to Book Value. However, Return on Asset has a notable influence. Additionally, both variables collectively have an effect on Price to Book Value.
Dampak Tingkat Pendidikan Teologi Pelayanan di GKII Daerah Kayan
Authors: Welikinsi
Published: September 2023

Tujuan penelitian yang terkait dengan tingkat pendidikan tergambarnya paradigma umum tentang tugas dan fungsi  Pekerja Gereja dalam meningkatkan kualitas dan kuantitas penatalayan gereja. Terpetanya kemampuan pekerja gereja menerjemahkan ilmu pengetahuan teologis dan praktis, serta keterampilan melayani dengan baik. Tergambarnya kemampuan pekerja gereja dalam menanggapi dan menyelesaikan persoalan dalam pelayanan gerejawi. Menemukan adanya gambaran tentang kemampuan pekerja gereja dalam upaya mengarahkan atau mempengaruhi orang untuk mencapai tujuan bersama. Menemukan haln ihwal mengenai kemampuan pekerja gereja dalam membangun dan mengembangkan hubungan-hubungan internal dan eksternal yang terikat pada pelayanan gereja.  Manfaat penenlitian:  bagi peneliti yakni penelitian ini merupakan sarana bagi upaya berkesinambungan dalam mengaplikasikan ilmu pengetahuan di bidang penelitian yang telah didapati selama proses studi, bagi Gereja, yaitu tersedianya analisis tentang dampak atau pengaruh tingkat pendidikan pekerja gereja di lingkungan Gereja Kemah Injil Indonesia Daerah Kayan, khususnya bagi jemaat lokal dalam rangka meningkatkan kualitas dan kuantitas pelayanan, bagi pekerja gereja, yaitu sebagai bentuk motivasi dan introspeksi diri terhadap upaya meningkatkan pelayanan gereja yang berkaitan dengan mendewasakan jemaat di dalam Kristus. Metode Penelitian yang dipergunakan dalam penelitian ini adalah metode penelitian kualitatif.  Bentuk penelitian ini memiliki sifat deskriptif. Hasil penelitian: paradigma umum tentang tugas atau fungsi Pekerja Gereja terkait dengan pengaruh terhadap kemampuan meningkatkan kualitas dan kuantitas penatalayan gereja; tingkat pendidikan teologi Pekerja Gereja berkaitan langsung dengan kemampuan menerjemahkan ilmu pengetahuan teologis dan praktis, serta keterampilan melayani dengan bai; tingkat Pendidikan teologi Pekerja Gereja yang berkaitan dengan kemampuan menanggapi dan menyelesaikan persoalan dalam pelayanan gerejawi; tingkat pendidikan teologi Pekerja Gereja yang berhubungan dengan kemampuan mengarahkan atau mempengaruhi orang untuk mencapai tujuan bersama; tingkat pendidikan teologi Pekerja Gereja berkaitan dengan kemampuan membangun hubungan-hubungan internal dan eksternal yang terikat pada pelayanan gereja.
Desarrollo de tareas de Matemáticas de alta demanda cognitiva con simuladores robóticos
Authors: Homa Agostinho Iaqchan Ryokiti
Published: September 2023

Se considera que las tecnologías potencian el aprendizaje matemático, pero la constan- te actualización de las tecnologías dificulta que los docentes actualicen sus conocimientos. El grupo de Estudios Curriculares en Educación Matemática (GECEM), vinculado al Programa de Posgrado en Enseñanza de Ciencias y Matemáticas (PPGECIM), de la Universidad Luterana de Brasil (ULBRA), en Canoas, en el estado de Rio Grande do Sul, Brasil, desarrolla simuladores de aprendizaje para ayudar a los profesores en su práctica en el aula con tareas de matemáticas de alto nivel de demanda cognitiva. Los simuladores de brazos robóticos se presentan como objetos de aprendizaje con ventajas sobre los reales porque son menos costosos, no requieren ajustes mecánicos, no se rompen, no necesitan ser transportados, siendo excelentes para actividades en el aula o en línea.
Potensi Interaksi Obat Antihipertensi Pada Pasien Penyakit Ginjal Kronik di Rumah Sakit Khusus Ginjal Bandung
Authors: Hardianti Hardianti , Herliany Yane Srie
Published: September 2023

Hipertensi merupakan salah satu faktor pemicu timbulnya penyakit ginjal kronik. Adanya kerusakan pembuluh darah dalam ginjal menyebabkan terjadinya penurunan kemampuan fungsi ginjal untuk menyaring (filtrasi) darah dengan baik. Penelitian ini bertujuan untuk mengevaluasi potensi interaksi obat antihipertensi yang digunakan pasien penyakit ginjal kronik di poliklinik penyakit dalam salah satu rumah sakit khusus ginjal di Bandung. Penelitian ini merupakan jenis penelitian non eksperimental bersifat deskriptif  kuantitatif dengan pengambilan data secara observasional mengambil data pada periode Juli - September 2019. Teknik pengambilan sampel diambil dari data rekam medis pasien sesuai kriteria inklusi dan ekslusi, didapatkan sampel sebanyak 225 rekam medis pasien. Hasil penelitian menunjukkan potensi interaksi obat antara antihipertensi yang digunakan, terdapat 172 kasus dengan persentase paling banyak pada tingkat keparahan moderate sebanyak 128 kasus (74,42 %), minor 30 kasus (17,44 %) dan major 14 kasus (8,14 %) dengan obat yang paling banyak menimbulkan interaksi adalah amlodipin dengan bisoprolol sebanyak 64 kasus. Potensi interaksi obat antihipertensi dengan obat golongan lain terdapat 279 kasus dengan nilai persentase paling banyak pada tingkat keparahan moderat (88,53%) dan kombinasi interaksi yang terbanyak adalah amlodipine + kalsium karbonat sebanyak 168 kasus.
Light pollution causes object collisions during local nocturnal manoeuvring flight by adult Manx Shearwaters Puffinus puffinus
Authors: Guilford Tim , Padget Oliver , Bond Sarah , Syposz Martyna
Published: September 2023

Understanding the detrimental effects of anthropogenic light on nocturnally mobile animals is a long-standing problem in conservation biology. Seabirds such as shearwaters and petrels can be especially affected, perhaps because of their propensity to fly close to the surface, making them vulnerable to encountering anthropogenic light sources. We investigated the influence of light pollution on adult Manx Shearwaters Puffinus puffinus at close range in foggy conditions. We recorded collisions with a building at a breeding colony for six consecutive pairs of intervals in which the house lights were left on as normal for 135 seconds, then turned off for 135 seconds. The relationship between lighting condition and collision frequency was highly significant, with a collision rate in the presence of lighting around 25 times that in its absence. Our results show that birds were clearly affected by the lights, by being either directly attracted, or disorientated during flight close to the structure. This could have been due to the light source itself, or an indirect effect of the all-round reflective glow in the fog perhaps interfering with visual or magnetic control inputs on both sides of the bird simultaneously. Our results suggest a mechanism by which the screening of artificial lights close to shearwater breeding areas, at least during foggy nights, could lead to improved welfare and survival at breeding colonies.
COVID-19 Sürecinde Bir Devlet Üniversitesindeki Sağlık Bilimleri Fakültesi Öğrencilerinin Uzaktan Eğitim Algıları
Authors: TUNA Rujnan , ŞAHİN Safiye
Published: September 2023

Amaç: COVID-19 virüsünün bulaşmasını engellemek amacıyla alınan önlemler neticesinde zorunlu olarak uzaktan eğitime geçilmiş ve üniversite öğrencileri bu durumdan etkilenmiştir. Bu çalışma ile sağlık bilimleri fakültesinde öğrenim gören üniversite öğrencilerinin COVID-19 pandemi sürecinde uygulanan uzaktan eğitime ilişkin algılarının belirlenmesi amaçlanmıştır.

Gereç ve Yöntem: Bu çalışma tanımlayıcı ve kesitsel olarak tasarlanmıştır. Araştırma verisi kapsam geçerliği yapılan yedi önermelik çevrimiçi anket yöntemi ile toplanmıştır. Araştırma İstanbul’daki bir devlet üniversitesinin sağlık bilimleri fakültesinde Aralık 2020-Ocak 2021 tarihleri arasında toplanmıştır. Araştırmanın örneklemini 261 öğrenci (hemşirelik, sağlık yönetimi ve sosyal hizmet) oluşturmuştur. Veriler SPSS 22 istatistik programında betimleyici (sayı, yüzde, ortalama ve standart sapma) yöntemlerle analiz edilmiştir.

Bulgular: Araştırmaya katılan öğrencilerin çoğunluğunun uzaktan eğitimi gelecekte tercih etmemesi (%44,8), geleneksel eğitimi uzaktan eğitime tercih etmesi (%76,6), uzaktan eğitim kalitesini tatmin edici bulmaması (%61,3), sınıf içi etkileşimin öğrenme üzerinde etkili olduğuna inanması (%85,8), ve uzaktan eğitimi mesleki uygulama derslerinin verilmesinde yetersiz kaldığına inanması (%88,9) nedenleriyle uzaktan eğitimi olumlu algılamadıkları (%46,4) bulunmuştur.

Sonuç: Sağlık bilimleri fakültesi öğrencileri tarafından uzaktan eğitimin etkin bir öğrenme aracı olarak görülmediği ve benimsenmediği söylenebilir.
Hipertansiyon Tanısı Almış 65 Yaş Üzeri Bireylerin İlaç Kullanımına İlişkin Sağlık İnançlarının Belirlenmesi
Authors: EFE Esra , DOĞAN Nurhan
Published: September 2023

Amaç: Bu çalışma hipertansiyon tanısı almış 65 yaş üzeri bireylerin ilaç kullanımına ilişkin sağlık inançlarını belirlemek amacıyla yapılmıştır.

Gereç ve Yöntem: Tanımlayıcı ve kesitsel türdeki bu çalışma, Ekim 2021-Ocak 2022 tarihleri arasında 65 yaş üzeri, hipertansiyon tanısı almış ve hipertansiyon ilacı reçete edilmiş 444 geriatrik bireyle yürütülmüştür. Araştırmada veriler, Kişisel Bilgi Formu ve İlaç Kullanmaya İlişkin Sağlık İnanç Ölçeği kullanılarak toplanmıştır.

Bulgular: Çalışmaya katılan 444 bireyin %55,2’si 65-69 yaş grubunda, %64,9’u kadın, %29,5’inin 6-10 yıldır hipertansiyon hastası ve %61,3’ünün ailesinde hipertansiyon öyküsü olduğu belirlenmiştir. Bireylerin %19,8’i ilaç alma zamanı için bir hatırlatıcı kullandığını, %76,8’i ilaçlarını düzenli kullandığını ve %42,1’i ise yan etkilerini bildiğini belirtmiştir. İlaç Kullanmaya İlişkin Sağlık İnanç Ölçeği’nin toplam puan ortalaması 148,15±12,36’dır. Yaş, cinsiyet, taburcu olurken eğitim alma, ilaçlar için hatırlatıcı kullanma, ilaçlarını düzenli kullanma, kullandıkları ilacın yan etkisini ve ne kadar süre ile kullanılması gerektiğini bilme gibi faktörlerin sağlık inanç ölçeği toplam puanlarını anlamlı düzeyde etkilediği saptanmıştır (p