bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating Contrastive Grammar Problems Iraqi EFL Learners Face in English-Arabic Translation
Authors: Bashara Amenah , Betti Mohammed
Published: September 2023

English and Arabic have many similarities and differences with regard to grammar. Consequently, the current paper is designed to investigate the grammatical problems that Iraqi EFL learners suffer from through the process of translation from English to Arabic. It draws upon contrastive analysis (CA) to help in solving the problems which encounter Iraqi EFL morning and evening learners. It aims at examining the contrastive grammatical difficulties and problems that Iraqi EFL learners encounter in English-Arabic translation; presenting a test for identifying the grammatical problems that EFL learners face in English-Arabic translation; providing solutions for such problems.  It uses a translation test that consists of 20 items for testing one hundred EFL learners of English department for morning studies and another one hundred for evening studies, college of Education, University of Thi-Qar for the academic year 2022-2023. The test is analysed and discussed. After implementing and discussing the test, the study concluded that hypothesis (1) is verified that the errors students committed are classified as being interlingual or intralingual; hypothesis (2) also verified that here are some aspects in English have no equivalents in Arabic; hypothesis (3) is refuted since tenses and the emphatic do take the highest number of errors that EFL learners (morning and evening participants) commit in English-Arabic translations; hypothesis (4) is partially accepted is partially accepted because of the other simple problems in Arabic-English translation. It is concluded that the majority of Iraqi EFL learners suffer from the tenses, emphatic do, word order, and sentence connectors in English-Arabic translation and both morning and evening students do not suffer from big problems in translating the gerund, Od and Oi, conditional sentences, negation, adjectives, medal auxiliaries, prepositions, and articles in English-Arabic translation
Legal Reconstruction of Standard Agreements with Exoneration Clauses on Peer-To-Peer Financial Technology Based on Justice Values
Authors: Maileni Dwi Afni , Sulistiyono Adi , Mashdurohatun Anis
Published: September 2023

This research aims to examine and analyze standard peer-to-peer lending contract agreements with exoneration clauses that are not based on the value of justice. To study and analyze the weaknesses that arise in implementing peer-to-peer lending Financial Technology agreements at this time. To study and analyze the reconstruction of standard agreements with exoneration clauses on peer-to-peer lending Financial Technology based on the value of justice. The method used in this research is sociological juridical. The paradigm in this research is constructivism. The theory used in this study is the Pancasila legal theory of justice as a grand theory, the working theory of law as a middle ranged theory, and the progressive theory as an applied theory. Based on the research conducted, it was found that standard peer-to-peer lending contract agreements with exoneration clauses that are not based on the value of justice are due to overlapping rules, the lack of reach of law enforcement in standard contracts made by Financial Technology institutions, and the influence of globalization which has resulted in the growth of financial institutions. technology is getting out of control. So it is necessary to amend the provisions of the Financial Services Authority Circular Letter Number 13/Seojk.07/2014 in which the financial services business actors are not only entitled to make procedures regarding standard agreements, but it is necessary to regulate the position of Financial Technology institutions in the Republic of Indonesia Financial Services Authority Regulation Indonesia Number 10/Pojk.05/2022 concerning Information Technology-Based Joint Funding Services is clear. It is necessary to regulate information on the process of public complaints against the OJK, especially in the case of Financial Technology institutions. It is also necessary to control sanctions related to Financial Technology that violates the law, especially in standard agreements with exoneration clauses.
Inflation Targeting, Exchange Rate Distortion and Output Stabilisation A Case of Zimbabwe Disinflation
Authors: Makoto Richard , Ngendakumana Leonidas
Published: September 2023

Inflation targeting (IT) is practised in many countries and the real effects of strict inflation targeting were investigated on several occasions and less on other variants of IT. The study investigates the effects of inflation targeting lite on output. In particular, the compatibility of inflation targeting lite with managed exchange rate regime on output stabilization. The inflation targeting regime, the operating environment and exchange rate regimes were reviewed for Zimbabwe. An ARDL model was adopted as the empirical strategy to investigate the compatibility problem and the real effects of IT lite. Modelling output as output gap, inflation targeting lite and the exchange rate regimes were found to be inconsistent with output stabilization. IT lite and exchange rate premium increased the output gap, however the interaction between IT lite and exchange rate premium had negative effects on output. These results hold for both the short run and long run. However, considering the official rate and parallel rate separately, parallel rate has a negative effect but its interaction with IT has positive effects. The study recommends that developing countries should consider the exchange rate systems before the adoption of IT as a monetary policy framework. A floating exchange rate seemed to be compatible with IT lite.
The Role of Corporate Image as Mediating the Marketing Mix for Treatment Decisions in Private Hospitals, Indonesia
Authors: Cristinawati Fransiska Maylina , Respati Harianto , Hariyanto Sugeng
Published: September 2023

The hospital is a place to obtain services that depend on the level of patient visits. The indicator for improving hospital services is determined by the utilization of health services through increasing the number of patient visits in selecting health services at the hospital. A good corporate image has an important role for the continuity of a business organization. A good corporate image will shape a decision to buy a product or service. Currently, there is not many certain study on marketing mix and the treatment decision as an marketing strategy for healthcare management system. The study to determine the relationship between the marketing mix and the treatment decision through corporate image by the researcher as a preliminary study that could open the horizons for future studies. This type of research used is quantitative research. The sample used was outpatients at a private hospital that met the inclusion criteria. The research instrument uses a questionnaire that will be distributed to patients or families of patients who have undergone examination and treatment at the hospital. This study conducted sampling outpatient polyclinic at Private Hospital with a total of 154 samples.The results were measured using a Likert scale. Data on marketing mix and the treatment decision through corporate image were analyzed by descriptive and linier regression statistics. According to the data analysis, the results show that all of marketing mix elements have a significant impact influences outpatient treatment decisions through corporate image (p value for all marketing mix elements is less than α = .05). There is a significant relationship between the marketing mix and the outpatient treatment decision through corporate image.
ANALISIS EFEKTIVITAS BIAYA TERAPI ANTIDIABETES PASIEN NEFROPATI DIABETES DI RUMAH SAKIT UMUM PUSAT (RSUP) FATMAWATI
Authors: Ema Nillafita Putri Kusuma
Published: September 2023

Diabetes Mellitus (DM) merupakan gangguan kesehatan yang menjadi salah satu penyebab kondisi darurat kesehatan global dengan progresitas penyakit yang sangat cepat di abad 21. Prevalensi diabetes melitus diprediksi akan terus meningkat setiap tahunnya, hingga mencapai 643 juta orang pada tahun 2030. Kondisi DM akan memunculkan sebuah risiko komplikasi baik komplikasi mikrovaskular ataupun makrovaskular, serta akan berdampak pada besaran biaya yang diperlukan untuk sebuah proses terapi medis yang berkelanjutan. Pertimbangan kondisi komplikasi pasien, efektivitas, risiko efek samping, dan harga obat akan sangat menentukan pilihan terapi dan keberhasilan proses terapi pasien. Tujuan dari penelitian ini adalah menentukan terapi antidiabetika yang lebih cost effective untuk pasien nefropati diabetik. Penelitian ini merupakan penelitian deskriptif non eksperimental dengan menggunakan data rekam medis pasien rawat jalan di Rumah Sakit Umum Pusat Fatmawati dalam jangka waktu 1 (satu) tahun. Berdasarkan perhitungan secara ACER penggunaan Glimepiride lebih cost effective, namun secara ICER penggunaan Gliquidone lebih cost effective dibandingkan dengan pilihan terapi yang lain.
PRINCIPAIS SEQUELAS RELACIONADAS À COVID-19: UMA REVISÃO DE LITERATURA
Authors: Barros José Paulo Ribeiro Alves de , Cardoso Maria do Socorro Orestes , Paz ElianaSantos Lyra da , Júnior Francisco Braga da Paz , Santana Kássia Regina de , Cruz Andreia Pereira da , Silva Lívian Nayane da Costa e , Guaraná Carlos Fernando Rodrigues
Published: September 2023

Objetivo: Este estudo buscou analisar as principais sequelas e complicações relacionadas à Covid-19, bem como descrever como impactam na qualidade de vida dos indivíduos. Metodologia: Para constituir esta revisão integrativa, foram selecionados entre os trabalhos consultados nos bancos de dados pesquisados 20 artigos que atenderam aos seguintes critérios: textos na forma de artigos, teses ou dissertações disponíveis na íntegra, que abordaram a temática, no idioma português ou inglês, publicado nos últimos quatro anos. Resultados e discussão: Foi possível evidenciar que os avanços do conhecimento acerca da Covid-19 e das sequelas que o acometimento pela fase aguda pode deixar na vida dos indivíduos estão sendo pesquisados. A síndrome pós-Covid-19 se caracteriza por sequelas deixadas após a fase aguda e que minimizam a qualidade de vida dos indivíduos.  Muitos são os sintomas persistentes nessa síndrome, como: cefaleia, tosse persistente, dispneia pós-esforço, distúrbios relacionados ao sono, anosmia e vertigem. Como a doença surgiu a poucos anos, suas sequelas ainda estão sendo pesquisadas, por isso há grande possibilidade da existência de outras manifestações clínicas pós-Covid que irão ser estudadas e listadas conforme novos estudos sobre essa temática forem surgindo. As sequelas da Covid-19 podem impactar na saúde do acometido pela doença, tanto na fase aguda quanto após semanas. Conclusão: As manifestações em longo prazo são diversas e que os sintomas variam desde respiratórios até neurológicos, bem como alterações na saúde mental.  As sequelas da Covid-19 interferem na qualidade de vida e tornam difícil a realização das atividades diárias e consequentemente afeta as dimensões da saúde geral, emocional e social dos indivíduos acometidos pela doença.
Traumatismo orofacial e a qualidade de vida relacionada à saúde bucal
Authors: Duarte Ana Vitória  Machado , Lourenço Calebe Carvalhêdo , Pessoa Camilla Lucena , Bezerra Cristina do Nascimento , Oliveira Giovana Gisele Costa , Costa Hillary Kananda da Silva , Lima Iasmym Andrade , Oliveira João Pedro da Costa , Monteles Karine Martins , Amarante Luana Oliveira , Rodrigues Rubens de Macedo , Santos Wharlley Silva , Santos Stanley Keynes Duarte dos
Published: September 2023

A região orofacial é uma das regiões corporais que mais são acometidas com danos traumáticos, em especial na dentição e nos tecidos moles adjacentes. A análise dos diferentes aspectos da saúde bucal relatadas pelo paciente faz parte da pesquisa sobre qualidade de vida relacionada à saúde bucal (QVRSB), que ajuda a melhorar a prestação de tratamento odontológico. Esta revisão sistemática objetiva analisar os impactos do trauma orofacial sobre a qualidade de vida relacionada à saúde bucal (QVRSB). Foi realizada busca nos bancos de dados PubMed, ScienceDirect, Scopus, Google Scholar e Scielo e com base na ferramenta PRISMA e na aplicação dos critérios de inclusão e exclusão foram selecionados 5 artigos para análise e discussão. Infere-se que a QVRSB dos pacientes é impactada pelas lesões traumáticas orofaciais, tendo relação diretamente proporcional, maior impacto imediatamente após o diagnóstico e de acordo com a gravidade do trauma. A maioria dos estudos limita-se a crianças e adolescentes, contudo, o traumatismo orofacial ocorre em qualquer idade. O questionário “condensed oral health impact profile – 14 (OHIP-14)” e suas adaptações são ferramentas importantes para os estudos sobre a QVRSB. Por fim, os estudos que relacionam a QVRSB e o trauma orofacial são importantes para retirar ensinamentos para a prática clínica dos atendimentos odontológicos.
Manejo e complicações relacionadas a corpos estranhos em otorrinolaringologia
Authors: Araújo Lívia Maria Figueiredo Teles de , Neto Edmundo Machado Ferraz Neto , Diniz Maria Clara Oliveira Padilha , Endo Amanda Hatsue Santana , Nóbrega Rafaela Germana Cavalcanti da , Rangel Ana Lívia de Andrade , Costa Lívia Gonçalves Santos , Ribeiro Renata Antonia Aguiar , Tenório Clara Maria Pinto , Pessoa Raissa Margarida de Araújo , Dantas Júnior Janeilson Jânio , Melo Brena Nunes
Published: September 2023

Este artigo busca apresentar o manejo e complicações relacionadas a corpos estranhos em otorrinolaringologia. O estudo trata-se de uma revisão integrativa da literatura. Foi possível assim estruturar a seguinte pergunta norteadora: “Quais as complicações e manejo relacionado a pacientes com corpos estranhos em otorrinolaringologia?”. Foi feito um levantamento através da biblioteca eletrônica sendo a Biblioteca Virtual em Saúde (BVS), sendo selecionada as seguintes bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medical Literatures Analysis and Retrieval System Online (MEDLINE). Com isso, foi utilizado os descritores consultados nos Descritores em Ciência e Saúde (DeCS), no mês de agosto de 2023, sendo: “Corpos estranhos”, “Otorrinolaringologia” e “Medicina Hospitalar”, utilizando o operador booleando AND entre os descritores quando combinados. Após a aplicação dos critérios de elegibilidade foram utilizados 7 artigos selecionados ao total. As complicações graves foram definidas como as que possuíam uma infecção profunda do pescoço, perfuração esofágica e mediastinite que necessitavam de hospitalização. Em torno de 80 a 90% dos CE ingeridos passam de forma espontânea e a taxa de complicações envolvem perfuração, laceração da mucosa e infecção, embora algumas sejam incomuns a morbidade associada pode causa internação hospitalar de até seis vezes mais longa do que a de pacientes sem complicações. A maioria das situações que levam a acidentes a CE são evitáveis, sendo necessário que se tenha melhorias na questão da formação dos otorrinolaringologistas a fim de evitar sérias complicações.
STRATEGI PENGEMBANGAN USAHA JAMU DALAM MEMPERTAHANKAN EKSISTENSI JAMU TRADISIONAL MBAH GEDONG DI REJOTANGAN TULUNGAGUNG
Authors: Bondan Subagyo  , Sawal Sartono  , Keny Deva Lagasa
Published: September 2023

Abstract

This research is motivated by the increasingly fierce competition in the business world, requiring business runners to develop a traditional herbal medicine business. Bydesigning an appropriate strategy, it is important for the survival of a business to maintainits existence. The aims of this research are: (1) to find out and analyze how the developmentstrategy in the marketing aspect of Mbah Gedong's traditional herbal medicine business (2)to find out things that can affect the development strategy of Mbah Gedong's traditionalherbal medicine business through SWOT analysis. This research is a qualitative descriptive.Data collection techniques used are interviews, observation, literature review, anddocumentation. Then the data analysis technique used SWOT analysis to find alternativestrategies used by Mbah Gedong's herbal medicine business. The results of the researchconducted indicate that the strategy used by Mbah Gedong's herbal medicine business is touse the marketing mix. Based on the SWOT analysis, the business position is in quadrant I.The strategy that needs to be implemented is a growth oriented strategy with strengths andthe availability of profitable opportunities.

Abstrak

Penelitian ini dilatarbelakangi oleh persaingan dunia bisnis yang semakin ketat, menuntut pelaku usaha untuk mengembangkan usaha produksi peracikan jamu tradisional.Dengan perancangan strategi yang sesuai penting untuk keberlangsungan hidup suatu usahadalam mempertahankan eksistensinya. Tujuan penelitian ini adalah: (1) untuk mengetahuidan menganalisis bagaimana strategi pengembangan pada aspek pemasaran usaha jamutradisional Mbah Gedong (2) untuk mengetahui hal – hal yang dapat mempengaruhi strategipengembangan pada usaha jamu tradisional Mbah Gedong melalui analisis SWOT.Penelitian ini merupakan deskriptif kualitatif. Teknik pengumpulan data yang digunakanyaitu wawancara, observasi, kajian pustaka, dan dokumentasi. Kemudian teknik analisis datamenggunakan analisis SWOT untuk mencari alternative strategy yang digunakan usahajamu Mbah Gedong. Hasil Penelitian yang dilakukan menunjukkan bahwa strategi yangdilakukan usaha jamu Mbah Gedong dengan menggunakan bauran pemasaran. Berdasarkananalisis SWOT posisi usaha pada kuadran I. Strategi yang perlu diterapkan yaitu growthoriented strategy dengan memiliki kekuatan dan tersedianya peluang yang dapatmenguntungkan.
Fat Intake, Fiber, Sodium and Sleep Quality with Hypertension in Pra Lansia
Authors: Rahayu Sina Dwi , Putriningtyas Natalia Desy
Published: September 2023

Hypertension is a disease when a person's blood pressure exceeds normal limits. Hypertension can be caused by controllable and uncontrollable factors. Consumption of foods low in fiber, high in fat and sodium is one of the causes factors that can be controlled. This research was to analyze the relationship between intake of fat, fiber, sodium and sleep quality to hypertension in the Central Magelang Health Center area. This case control study used purposive sampling technique with a minimum number of cases and controls for each group of 47 subjects. The inclusion criteria for case subjects were grade 1 and 2 hypertension patients aged 45-59 years and had taken hypertension medication for the last 6 months. The inclusion criteria for the control group were men or women aged 45-59 years who did not had hypertension. Data was obtained by interviews using the SQ-FFQ and PSQI questionnaires. Data  was performed using univariate analysis, bivariate analysis with the Spearman test and multivariate analysis with a linear regression test. The results obtained were fat and fiber intake had significant relationship (p-value=0,000) and (p-value=0,014) to systolic blood pressure. Sodium intake and sleep quality had significant relationship ??(p-value=0,000) and (p-value=0,000) to systolic blood pressure and diastolic blood pressure (p-value=0,047) and (p-value=0,003). Fat and fiber intake were related to systolic blood pressure, and sodium intake and sleep quality were related to systolic and diastolic blood pressure in hypertensive patients.
REFLECTION ON MINING EXTRACTION-Depredation and Appropriation of Natural Resources by Multinational Companies
Authors: Imelda Ortiz Medina  , Jorge Martinez Perez  , Tania Indira Arreola Medina
Published: September 2023

Mining activity, particularly mega-mining, is an economic activity that has boomed in recent decades. This activity is carried out by multinational companies, who have appropriated natural resources, particularly metals and minerals, which, after carrying out the extraction, ghost towns are left, impoverished regions where agricultural activity is no longer possible. Therefore, the central reflection of this research is: What does mining contribute? The main contribution of mining is the depredation of the planet and the impoverishment of the towns from which the resource is extracted. This is descriptive exploratory research, whose objective is to motivate a reflection on the depredation, appropriation, and dispossession of resources by a small group of companies.
KEYWORDS: natural resources, depredation of the ecosystem, dispossession of resources, mega-mining, economic growth.
INSOLVENCY AND BANKRUPTCY CODE: A STUDY OF INDIAN BANKS WITH REFERENCE TO ALTMAN Z SCORE
Authors: Dr. Lokeshnath B  , Sandhya M
Published: September 2023

The implementation of the Insolvency and Bankruptcy Code 2016, which has been carried out in phases since August 5, 2016, was instituted with the aim of revamping the antiquated and intricate corporate insolvency regulations in India. This legislative measure was designed to tackle the pervasive issue of non-performing loans, which has had far-reaching consequences for the banking industry and the availability of credit within the broader economy. However, the unusual and surprising actions taken by the Reserve Bank of India, the central bank of India, to list delinquent borrowers and instruct banks to commence insolvency procedures against them, demonstrate a remarkable level of speed and determination. One notable illustration is the case of Essar Steel, which has encountered a default on loans amounting to around $6.9 billion and is presently undergoing a distressed sale in accordance with the Code. In light of the proactive implementation of the Code by Indian banks, as mandated by the Reserve Bank, and the commendable quality of available assets, it becomes imperative for foreign debt and equity investors to have a comprehensive understanding of the Code, along with the attendant obstacles and prospects it presents. The current investigation employed the Altman-Z score model to forecast the level of safety exhibited by banks in India with respect to potential insolvency and bankruptcy. The banks that were chosen for this study were picked based on specific criteria. The analysis conducted to assess the safety of these banks relied on information that was published in their respective Annual Reports. The research indicates that a significant proportion of Indian banks exhibit a higher level of safety in relation to insolvency and bankruptcy. The Altman-Z score analysis revealed that the performance of banks in India was strong during the first eight years of the study period. However, notable variations were observed during the latter two years of the study period. It is recommended that bank management proactively address these substantial disparities to minimise the risk of insolvency and bankruptcy.
KEY WORDS: Banking Governance, Banking Regulation, Banking Sustainability
Kajian Komoditas Unggulan Perikanan Tangkap Kabupaten Situbondo Berdasarkan Data Penangkapan Ikan
Authors: Pahlewi Anita Diah , Handayani Creani
Published: September 2023

The capture fisheries sector is one of the sectors that play an important role in national economic development, provision of protein food, foreign exchange capture, and employment opportunities. The capture fisheries sector makes a major contribution as a leading commodity in Situbondo Regency with the longest coastline in East Java. Leading commodities are needed as an effort to determine development in the fisheries sector and can improve the regional economy. The purpose of this study is to discuss the calculation of superior fisheries commodities in 4 Districts of Situbondo Regency that have the greatest catch potential using the Location Quotient (LQ) method. LQ measures the specialization of economic activity through a comparative approach to get an overview in determining the leading sector as the leading sector of industrial economic activity. Based on the Location Quotient (LQ) method, the leading capture fisheries commodities in Besuki District are Layang, Teri, and Tongkol; Panarukan District, namely Kakap, Pari, Teri, Rajungan, Crab, shrimp, and other fish; Jangkar District, namely Petek, Beloso, Bambang, Kakap, Kurisi, Cucut, Bawal, Selar, Belanak, Teri, Crab, Layur fish; Banyuputih District, namely Petek, Beloso, Belanak, Teri, and Layur fish.
Perbandingan Desalinasi Air Laut Berbasis Metode Evaporasi Dengan Tenaga Panas Api Dan Matahari
Authors: Silviyanti Nurul Amalia , Putri Helmilia , Ramadhan Alfarish
Published: September 2023

Our Earth is a blue planet, two-thirds of which is water. However, 20% of the earth's human population suffers from a lack of clean water. Desalination is the process of converting seawater into fresh water. This research aims to convert seawater into potable fresh water by evaporation using heat energy. The heat energy used is heat from burning fire and heat from sunray. These two energy sources will be compared and analyzed for their efficiency in desalinating seawater into fresh water. Heating using fire is done by burning twigs and dry leaves, and then two glass bottles are connected to the mouth of the bottle so that there is no air in or out. The collected water vapor will flow into the empty bottle. The second method uses sunray for heating. The two clear bottles are connected with a small pipe at the mouths of the bottles. Seawater is collected in the bottle and then dried under direct sunlight. The evaporated water will pass through the connecting pipe and gather in the empty bottle above. Fresh water produced from heating using fire was collected as much as ±7 ml in a span of 20 minutes, while heating using sunray can produce ±2 ml of fresh water in a span of 70 minutes or 1 hour 10 minutes.
Studi Eksperimental Laju Pertumbuhan Fouling Pada Pelat Besi Dan Alumunium Dengan Metode Pelapisan Cat Dan Lilin
Authors: Setiawan Mohammad Wahyu Dwi , Fadlurrohman Amjad Mulkus , Prameswari Grandys , Sakinah Wazirotus
Published: September 2023

The majority of offshore buildings are made of metal materials such as steel, aluminum, and so on. Metallic materials have the potential for damage due to corrosion and fouling growth. This requires regular maintenance and repair to prevent damage to an offshore building structure. Therefore, research was conducted on the rate of fouling growth through the mechanism of testing steel and aluminum materials using the iron paint coating method and wax as an inhibitor with the immersion method in marine waters in the Marina Boom beach area of Banyuwangi Regency. The results obtained in this study are the Daily Growth Rate (DGR) value. The highest DGR value is on steel material using iron paint coating with a value of 0.1828 grams. The lowest DGR value is in aluminum material using wax coating with a value of 0.0744 grams. So it can be concluded that aluminum material has better resistance to fouling growth compared to steel material and the coating method using wax is more effective for inhibiting or as an inhibitor of fouling growth compared to iron paint.
OTONOMI DESA ADAT: SEBUAH FATAMORGANA? KASUS DARI DESA ADAT INTARAN, BALI, INDONESIA
Authors: Rahmatunnisa Mudiyati , Ramaditya Fauzan , Putra Haelvyn Pratagrahana , Khairunnisa Anandya
Published: September 2023

This study examines the empirical experience of indigenous village autonomy in Indonesia as normatively regulated in the 1945 Constitution and the recent 2014 Law on Regional Government. The prolonged debate by many on the issue has mainly focused on how autonomous indigenous villages have actually been due to various forms of state intervention (also referred to as "stateization"). This study specifically identifies a number of empirical practices of autonomy in the Desa Adat Intaran of Bali Province. The case study provides a fertile ground for a variety of information related to the subject matter amidst the recent developments in the COVID-19 pandemic recovery efforts and the strong resistance of village communities to the LNG Terminal development project on Mertasari Beach by the Central Government and Bali Province in 2022 within the territory of Desa Adat Intaran. This study is particularly important in terms of adding current data and information to the current debate on the practice of indigenous village autonomy in Indonesia. This research utilizes qualitative research methods with a series of interviews, Focus Group Discussions as well as literature studies as data collection techniques. Triangulation techniques were also used to validate the qualitative data. The study argues that there has been noticeable state intervention in the implementation of autonomy of Desa Adat Intaran both in terms of institutions, programs and the allocated village budget. This finding confirms that there is a large gap between normative indigenous village autonomy and actual practice.
Wpływ herbicydów na zachwaszczenie łanu pszenicy ozimej i jarej
Authors: Klimont Krzysztof
Published: September 2023

Badano wpływ herbicydów: Aminopielik D — 3 l·ha-1, Chwastox D — 5 l·ha-1, Granstar 75DF — 30 g·ha-1 na zachwaszczenie łanu pszenicy ozimej odm. Elena i pszenicy jarej odm. Torka.W doświadczeniu zastosowano obiekt kontrolny nieopryskiwany i nieodchwaszczany. Eksperyment przeprowadzono metodą bloków losowanych w czterech powtórzeniach na czarnoziemie zdegradowanym wytworzonym z lessu, kompleks pszenny bardzo dobry.W badaniach oceniano: skład gatunkowy, liczbę oraz powietrznie suchą masę chwastów na m2. Stwierdzono, że zastosowane herbicydy znacznie modyfikowały i ograniczały skład gatunkowy i liczbę chwastów oraz obniżały ich powietrznie suchą masę. Najbardziej aktywny w zwalczaniu chwastów w łanie pszenic okazał się Granstar 75DF, Chwastox D działał pośrednio, a najmniej skuteczny był Aminopielik D.
An overview of current advances and pharmaceutical uses of 3D and 4D printing
Authors: Sharma Pankaj , Jain Vinay
Published: September 2023

The development of patient-specific prosthetics, medication administration, the manufacture of tissues and organs, and surgical planning have all benefited significantly from the use of three-dimensional (3D) printing during the past few decades. The enthusiasm for customized healthcare has increased because the United States of America launched its Precision Medicine Initiative in 2015. In a nutshell, the phrase “personalized medicine” refers to medical care that is tailored to the patient. Nevertheless, the biomedical materials utilized in 3D printing are often stable and can’t react or be adaptive and intelligent in the body’s interior environment. Ex-situ fabrication of these substances, which includes printing on a flat substrate before releasing it onto the target surface, may cause a discrepancy between the printed portion and the target areas. The 3D printing is one method that might be used to provide customized treatment. The four-dimensional (4D) printing is developed while employing components that can be tweaked with stimulation. Several researchers have been looking at a new area recently that blends medicines with 3D and 4D printing. The development of 4D printing overcomes a number of these issues and creates a promising future for the biomedical industry. Smart materials that have been pre-programmed can be used in 4D printing to create structures that react interactively to outside stimuli. Despite these benefits, dynamic materials created using 4D technology remain in their development. As a result, several ideas for pharmaceutical products and formulas that may be customized and printed have emerged. Furthermore, Spritam®, the first medicine produced by 3D printing, has indeed reached a medical facility. This paper offers a summary of several 3D and 4D printing technologies and how they are used in the pharmaceutical industry for customized medicine and drug delivery systems.
Retrospective immunophenotypical evaluation of MET, PD-1/PD-L1, and mTOR pathways in primary tumors and pulmonary metastases of renal cell carcinoma: the RIVELATOR study addresses the issue of biomarkers heterogeneity
Authors: Bersanelli Melissa , Gnetti Letizia , Pilato Francesco Paolo , Varotti Elena , Quaini Federico , Campanini Nicoletta , Rapacchi Elena , Camisa Roberta , Carbognani Paolo , Silini Enrico Maria , Rusca Michele , Leonardi Francesco , Maestroni Umberto , Rizzo Mimma , Brunelli Matteo , Buti Sebastiano , Ampollini Luca
Published: September 2023

Aim: In renal cell carcinoma (RCC), tumor heterogeneity generated challenges to biomarker development and therapeutic management, often becoming responsible for primary and acquired drug resistance. This study aimed to assess the inter-tumoral, intra-tumoral, and intra-lesional heterogeneity of known druggable targets in metastatic RCC (mRCC).
Methods: The RIVELATOR study was a monocenter retrospective analysis of biological samples from 25 cases of primary RCC and their paired pulmonary metastases. The biomarkers analyzed included MET, mTOR, PD-1/PD-L1 pathways and the immune context.
Results: High multi-level heterogeneity was demonstrated. MET was the most reliable biomarker, with the lowest intratumor heterogeneity: the positive mutual correlation between MET expression in primary tumors and their metastases had a significantly proportional intensity (P = 0.038). The intratumor heterogeneity grade was significantly higher for the mTOR pathway proteins. Combined immunophenotypical expression patterns and their correlations with the immune context were uncovered [i.e., mTOR expression in the metastases positively correlated with PD-L1 expression in tumor-infiltrating lymphocytes (TILs), P = 0.019; MET expression was related to PD-1 expression on TILs (P = 0.041, ρ = 0.41) and peritumoral lymphocytes (RILs; P = 0.013, ρ = 0.49)], suggesting the possibility of predicting drug response or resistance to tyrosine kinase, mTOR, or immune checkpoint inhibitors.
Conclusions: In mRCC, multiple and multi-level assays of potentially predictive biomarkers are needed for their reliable translation into clinical practice. The easy-to-use immunohistochemical method of the present study allowed the identification of different combined expression patterns, providing cues for planning the management of systemic treatment combinations and sequences in an mRCC patient population. The quantitative heterogeneity of the investigated biomarkers suggests that multiple intralesional assays are needed to consider the assessment reliable for clinical considerations.
Síndrome de Flood, una rara complicación en el paciente cirrótico con ascitis
Authors: Fernández García R , Lecuona Muñoz M , Lancho Muñoz A , Redondo Cerezo E , López Garrido MÁ
Published: September 2023

El síndrome de Flood es una patología infrecuente, sin prevalencia claramente descrita, que se produce por complicación de una hernia umbilical en pacientes cirróticos con ascitis. Consiste en la ruptura del saco herniario hacia la piel y la salida de líquido ascítico a través del mismo. Habitualmente se relaciona con el grado de hepatopatía, siendo más frecuente en aquellos pacientes con ascitis refractaria y hepatopatía avanzada. Su importancia radica en su elevada mortalidad, cercana al 50%, el riesgo de complicaciones, como la peritonitis bacteriana secundaria, y a la ausencia de un algoritmo de manejo establecido. Presentamos el caso de un paciente cirrótico con ascitis refractaria y hernia umbilical, con salida espontánea de líquido ascítico a través de la misma. Pese a la buena respuesta inicial al tratamiento conservador y a la reducción de la presión intraabdominal, se produjo un deterioro progresivo del estado del paciente, con fallecimiento del mismo, que expone la gravedad de este cuadro.
Edukasi Kesehatan Reproduksi Pencegahan dan Penanggulangan Penyakit Infeksi Menular Seksual pada Ibu-Ibu Pasca Gempa di Cianjur
Authors: Mudarris Nelil , Oktaviany Dyan , Khoiriyah Siti , Dwiyani Tatik , Kumalasari Umaya , Marliyani Rinasari , Erin Riani Frina
Published: September 2023

There was a 5.6 earthquake in the Cianjur area of West Java. This earthquake caused 327 fatalities, 13 people missing, more than 700 people injured and more than 2,000 houses damaged. In addition to causing casualties and material losses, this disaster also caused reproductive health problems. The most prominent problem occurred in mothers who complained of itching in the female area due to the lack of clean water supply after the earthquake. The purpose of this study was to improve reproductive health knowledge about the prevention and control of STIs in post-earthquake mothers in Cibulakan Village, Cugenang District, Cianjur. The method used by providing education using leaflet media related to reproductive health about the prevention and control of STIs in post-earthquake mothers. Education is given directly, the evaluation design of providing education is carried out by providing (pretest) and final evaluation (posttest) with the target, namely post-earthquake mothers in Cibulakan Village, Cugenang District, Cianjur. The statistical test is Paired sample T-test. The result was an increase in the knowledge of post-earthquake mothers after being given education by 48.7% so that at the end of the provision of education all post-earthquake mothers had high knowledge about reproductive health and prevention of sexually transmitted infections. The conclusion obtained is that there is an effectiveness of providing education using leaflet media in increasing knowledge.
Non-coding RNAs: The potential biomarker or therapeutic target in hepatic ischemia-reperfusion injury
Authors: Shao Jia-Li , Wang Li-Juan , Xiao Ji , Yang Jin-Feng
Published: September 2023

Delayed passage of meconium or constipation during the perinatal period is traditionally regarded as a signal to initiate further work up to evaluate for serious diagnoses such as Hirschsprung’s disease (HD), meconium ileus due to Cystic Fibrosis, etc. The diagnosis of HD particularly warrants invasive testing to confirm the diagnosis, such as anorectal manometry or rectal suction biopsy. What if there was another etiology of perinatal constipation, that is far lesser known? Cow’s milk protein allergy (CMPA) is often diagnosed in infants within the first few weeks of life, however, there are studies that show that the CMPA allergen can be passed from mother to an infant in-utero, therefore allowing symptoms to show as early as day one of life. The presentation is more atypical, with perinatal constipation rather than with bloody stools, diarrhea, and vomiting. The diagnosis and management would be avoidance of cow's milk protein within the diet, with results and symptom improvement in patients immediately. Therefore, we discuss whether an alternative pathway to address perinatal constipation should be further discussed and implemented to potentially avoid invasive techniques in patients. This entails first ruling out CMPA with safe, noninvasive techniques with diet modification, and if unsuccessful, then moving forward with further diagnostic modalities.
Diabetes exacerbates inflammatory bowel disease in mice with diet-induced obesity
Authors: Francis Kendra L , Alonge Kimberly M , Pacheco Maria Cristina , Hu Shannon J , Krutzsch Cody A , Morton Gregory J , Schwartz Michael W , Scarlett Jarrad M
Published: September 2023

Delayed passage of meconium or constipation during the perinatal period is traditionally regarded as a signal to initiate further work up to evaluate for serious diagnoses such as Hirschsprung’s disease (HD), meconium ileus due to Cystic Fibrosis, etc. The diagnosis of HD particularly warrants invasive testing to confirm the diagnosis, such as anorectal manometry or rectal suction biopsy. What if there was another etiology of perinatal constipation, that is far lesser known? Cow’s milk protein allergy (CMPA) is often diagnosed in infants within the first few weeks of life, however, there are studies that show that the CMPA allergen can be passed from mother to an infant in-utero, therefore allowing symptoms to show as early as day one of life. The presentation is more atypical, with perinatal constipation rather than with bloody stools, diarrhea, and vomiting. The diagnosis and management would be avoidance of cow's milk protein within the diet, with results and symptom improvement in patients immediately. Therefore, we discuss whether an alternative pathway to address perinatal constipation should be further discussed and implemented to potentially avoid invasive techniques in patients. This entails first ruling out CMPA with safe, noninvasive techniques with diet modification, and if unsuccessful, then moving forward with further diagnostic modalities.
Novel deformable self-assembled magnetic anastomosis ring for endoscopic treatment of colonic stenosis via natural orifice
Authors: Zhang Miao-Miao , Zhao Guang-Bin , Zhang Han-Zhi , Xu Shu-Qin , Shi Ai-Hua , Mao Jian-Qi , Gai Jing-Ci , Zhang Yu-Han , Ma Jia , Li Yun , Lyu Yi , Yan Xiao-Peng
Published: September 2023

Delayed passage of meconium or constipation during the perinatal period is traditionally regarded as a signal to initiate further work up to evaluate for serious diagnoses such as Hirschsprung’s disease (HD), meconium ileus due to Cystic Fibrosis, etc. The diagnosis of HD particularly warrants invasive testing to confirm the diagnosis, such as anorectal manometry or rectal suction biopsy. What if there was another etiology of perinatal constipation, that is far lesser known? Cow’s milk protein allergy (CMPA) is often diagnosed in infants within the first few weeks of life, however, there are studies that show that the CMPA allergen can be passed from mother to an infant in-utero, therefore allowing symptoms to show as early as day one of life. The presentation is more atypical, with perinatal constipation rather than with bloody stools, diarrhea, and vomiting. The diagnosis and management would be avoidance of cow's milk protein within the diet, with results and symptom improvement in patients immediately. Therefore, we discuss whether an alternative pathway to address perinatal constipation should be further discussed and implemented to potentially avoid invasive techniques in patients. This entails first ruling out CMPA with safe, noninvasive techniques with diet modification, and if unsuccessful, then moving forward with further diagnostic modalities.
Pelatihan Pembuatan Sabun dari Ecoenzym dan Limbah Minyak Goreng sebagai Rintisan Sosiopreneur di Kalangan Ibu-Ibu Graha Aradea Rt. 04 Rw. 12 Desa Ciherang Bogor
Authors: Kusumayanti Diah
Published: September 2023

Indonesia merupakan Negara yang memiliki kekayaan dari unsur bio yang melimpah. Indonesia juga memiliki jumlah penduduk yang besar. Potensi ini memicu adanya peningkatan pembuangan sampah yang banyak dan penyerapan penggunaan sumberdaya yang banyak dalam aktifitas sehari-hari. Sabun merupakan kebutuhan pokok yang digunakan setiap hari. Potensi pengelolaan limbah dari kegiatan rumah tangga untuk dijadikan sabun merupakan salah satu solusi untuk mengurangi pembuangan sampah yang dapat mencemari lingkungan. Pelatihan pembuatan sabun dari minyak jelantah merupakan salah satu kegiatan yang dapat memberikan wawasan kepada masyarakat mengenai pengelolaan limbah rumah tangga yang dapat meningkatkan nilai guna dan nilai tambah. Kegiatan pelatihan ini memberikan wawasan untuk membuat produk yang memiliki nilai jual dan wawasan dalam pemasaran produk. Kegiatan pelatihan ini juga memberikan wawasan mengenai bagaimana membuat kemasan, membentuk produk menarik dan potensi penjualan untuk produk sabun dari minyak jelantah ini. Minyak jelantah juga dapat dimanfaatkan untuk pembuatan lilin aroma terapi. Kegiatan ini tidak hanya membuat sabun dari minyak bekas tapi juga menggunakan minyak nabati untuk keperluan mandi dengan menggunakan ecoenzym. Ecoenzym merukan produk dari pemanfaatan limbah kulit buah yang difermentasikan. Pembuatan sabun dari ecoenzym ini dapat meningkatkan pemberdayaan masyarakat mengenai nilai tambah ekonomi dari pembuatan sabun. Kegiatan ini dirancang agar masyarakat dapat mengembangkan potensi diri dan lingkungannya untuk mencintai lingkungan dengan mengelola sampah dengan baik, sehingga menciptakan lingkungan yang bersih dan sehat serta dapat meningkatkan pendapatan keluarga. Kegiatan ini juga dapat mendukung kegiatan untuk membentuk sociopreneur di lingkungan perumahan graha aradea.
SÍNDROME DE BURNOUT ENTRE SOCORRISTAS DO ATENDIMENTO MÓVEL PRÉ-HOSPITALAR DE GUARAPUAVA-PR
Authors: Oliveira LK , Araújo ART , Malaquias TSM , Pitilin ÉB , Trincaus MR , Pinheiro RHP , Jerônimo DVZ , Pelazza BB , Soares LG , Lentsck MH
Published: September 2023

Objetivo: Verificar a ocorrência da Síndrome de burnout entre socorristas que atuam no atendimento pré-hospitalar de Guarapuava, Paraná. Métodos: Trata-se de uma pesquisa transversal quantitativa, realizada com profissionais que atuam no atendimento pré-hospitalar de uma cidade do interior do Paraná. Foram coletados os dados através do questionário de dados sociodemográficos (QSETS) e Copenhague Burnout Inventory (CBI). Participaram da pesquisa 43 sujeitos, sendo composta por socorristas do SAMU (serviço de atendimento móvel de urgência) e bombeiros militares. Resultados: No presente estudo, pode-se observar escore geral para Burnout apresentaram-se baixos quando observados de forma ampla. Quando visto de modo individual foi possível identificar que 20,9% dos profissionais possui a síndrome, destaque também para os domínios pessoal e trabalho representando 46,5%. Conclusão: Foi possível identificar a presença da Síndrome nessa população, além de sinais sugestivos de vulnerabilidades ao surgimento dela nesta população, principalmente nos militares, devido aos altos níveis de estresse enfrentados por tais socorristas, na atuação da sua profissão.
A PERFORMANCE ANALYSIS OF TRANSMISSION LINE DIFFERENTIAL PROTECTION
Authors: Prado Igor Ferreira , MEDEIROS R. P. , COSTA F. B. , SILVA K. M.
Published: September 2023

This work accomplishes a comparative analysis between two transmission line differential protection methodologies available in commercial relays: percentage and alpha-plane differential protections. In order to verify the operation limits of the protections, several internal and external faults were simulated considering variations of the fault location, fault inception angle, fault impedance, and TC saturation. The alpha-plane method presented was the most accurate and fastest since the sequence units were not influenced by the fault impedance.
GRUPOTERAPIA NO CONTEXTO HOSPITALAR: UM RELATO DE EXPERIÊNCIA
Authors: Bender Mariluza Sott , Freitas Suelen Machado de , Etges Bárbara Suzanne , Silva Caroline Plates da , Pfeifer Ariela Mazuim , Rodrigues Luana Molz , Garcia Edna Linhares
Published: September 2023

OBJETIVO: Discutir as possibilidades de trabalho do psicólogo hospitalar sob a ótica de intervenções grupais, a partir de um relato de experiência. MÉTODOS: Trata-se de uma pesquisa de cunho qualitativo, que se pauta no relato de experiência das atividades grupais de educação em saúde, atenção à gestação de alto risco, atenção ao puerpério e grupo aconchego, realizadas entre outubro de 2021 a junho de 2023. RESULTADOS: foram realizados 42 encontros grupais, com alcance de 339 participantes, entre pacientes, familiares e/ou acompanhantes. CONCLUSÃO: Os grupos permitiram a troca de experiências de vida, produzir sentidos a partir das temáticas abordadas e ampliar o conhecimento acerca dos conteúdos presentes cotidianamente em suas vidas, mas sobre os quais não se permitiam refletir.