bluuebunny/crossref_metadata_2025 huggingface dataset:
‘Pioneer’ Elm
Authors: Townsend A. M. , Masters W. O.
Published: October 2022

The American elm, Ulmus americana L., has proven itself to be particularly well adapted to urban environments. Unfortunately, Dutch elm disease, caused by the fungus Ceratocystis ulmi (Buism.) C. Moreau, has limited use of this species. The ‘Pioneer’ hybrid elm is a product of a USDA program to develop disease resistant elm clones which can be planted as substitutes for American elm.
‘Columbia’ and ‘Liberty’ Planetrees
Authors: Santamour Frank S.
Published: October 2022

‘Columbia’ and ‘Liberty’ planetrees (Platanus) are the 1st cultivars to be developed by controlled crossing between the American sycamore (P. occidentalis L.) and the Oriental plane (P. orientalis L.). They are outstanding in their high degree of resistance to sycamore anthracnose disease caused by the native North American fungus Gnomonia platani Kleb. to which the American species generally is susceptible. Both cultivars exhibit the inherent ability to compartmentalize trunk wounds and are reasonably resistant to powdery mildew pathogens. The common name “planetree” is used here to denote species and hybrids of Platanus because it is acceptable at the international level. Although “sycamore” is used extensively in the United States, that term in England and much of Europe refers to Acer pseudoplatanus L., the sycamore maple.
‘Centennial’ Baccharis Interspecific Hybrid
Authors: Won Lee Chi , Thompson Anson E. , Jones Warren D. , Hogan LeMoyne
Published: October 2022

The interspecific baccharis hybrid ‘Centennial’ has been released by the Univ. of Arizona Agricultural Experiment Station as a landscape plant suited for arid regions. The name ‘Centennial’ was given to commemorate the 100th year of the opening of the Univ. of Arizona as a land grant college.
Effects of Tree Vigor and Bloom Delay by Evaporative Cooling on Frost Hardiness of ‘Bartlett’ Pear Buds, Flowers, and Small Fruit1
Authors: Strang John G. , Lombard Porter B. , Westwood M. N.
Published: October 2022

Controlled freezing tests showed no hardiness differences between comparable floral developmental stages on weak and vigorous ‘Bartlett’ (Pyrus communis L.) pear trees. Bloom delay through evaporative cooling resulted in a loss of hardiness beyond that found earlier in the season on non-misted trees for similar stages of development, although a certain degree of frost protection was gained through bloom delay.
Analysis of Indoleacetic Acid by the Nitrogen-Phosphorus Detector Gas Chromatograph1
Authors: Martin George C. , Nishijima Chic , Labavitch John M.
Published: October 2022

A method was devised for quantitation of methylated indoleacetic (MeIAA) using a nitrogen-phosphorus (N-P) detector gas chromatograph with sensitivity greater than 5 pg MeIAA. Parameters are described for use conditions of the N-P detector.
Detection of Cytokinins Using a Gas Chromatograph Equipped with a Sensitive Nitrogen-Phosphorus Detector1
Authors: Zelleke Asfaw , Martin George C. , Labavitch John M.
Published: October 2022

A gas chromatograph equipped with a nitrogen-phosphorus detector was used for quantitation of cytokinins. The described system, utilizing permethylated derivatives, will detect as little as 0.1 pg adenine, isopentenyl adenine, benzylamino purine, and kinetin, and 10 pg zeatin. As with all highly sensitive instrumentation, scrupulous procedures for sample preparation are essential.
Onion Plant Size and Timing for Ethephon-induced Inhibition of Bolting1
Authors: Izquierdo Juan , Corgan J. N.
Published: October 2022

Late-winter application of 5000 ppm (2-chloroethyl)phosphonic acid (ethephon) to fall-seeded short- day onions (Allium cepa L.) retarded leaf growth and inhibited bolting. Bolting inhibition was significantly correlated with bulb diameter at time of treatment. Bolting inhibition was greatest when bulb diameter was 0.9 to 1.6 cm at time of treatment. Bulb diameter in late February or early March was an effective criterion for the effectiveness of ethephon treatment to reduce bolting. When ethephon treatments greatly reduced bolting, the number of harvestable bulbs and yields were increased, but when bolting percentage in control plots was low, ethephon reduced yield by decreasing average bulb weight at harvest.
An Influence of Water Stress at Different Growth Stages on Yield and Quality of Lettuce Seed1
Authors: Izzeldin Hassan , Lippert L. F. , Takatori F. H.
Published: October 2022

The effects of soil moisture deficit on yield and quality of head lettuce seed (Lactuca sativa L.) were studied. Three moisture levels (−0.3, −0.8 and −5.0 bars) were imposed upon lettuce plants continuously or in various combinations during vegetative and reproductive growth. Highest seed yields were obtained from treatments of intermediate water deficit during vegetative growth. Severe stress significantly reduced seed yields when introduced during either vegetative or reproductive growth. These treatments resulted in the lowest average number of seeds/seed head and seed heads/plant. Average seed weights were highest from plants exposed to severe stress for extended periods. Lowest average seed weights were produced on plants grown in adequate moisture treatments. Seed length, width, thickness and volume correlated with seed weight in response to soil moisture deficits. Germination was high in all treatments (97-100%). The lowest percentage abnormal seedlings observed during germination were obtained from seed developed on plants in severe and intermediate water deficit treatments. Seeds from these same treatments also produced the most vigorous seedlings, based on radicle length. Moisture levels conducive to highest seed yield generally produced lower quality seeds. Intermediate water deficits during vegetative and reproductive growth of lettuce plants appear to produce highest seed yields together with adequate seed quality.
Influence of Hand Picking Prior to Optimum and Late Timing of Machine Harvesting on Yield and Quality of A-5344 Strawberries1
Authors: Morris J. R. , Spayd S. E. , Cawthon D. L. , Kattan A. A. , Nelson G. S.
Published: October 2022

The response of an Arkansas breeding-line 5344 of strawberry (Fragaria X ananassa Duch.) to 0, 1 or 2 hand pickings prior to once-over machine harvest and to the timing of the machine harvest was examined for 3 years on the same planting. Increased yields from 1 or 2 hand pickings prior to machine harvest were lost by delaying machine harvest past the estimated optimum time (80 to 85% ripe fruit). Machine-harvested yield was reduced by hand picking and/or by delaying the time of machine harvest past the optimum period. Machine- harvested fruit quality was reduced in % soluble solids, acidity and color compared to the quality of hand-picked fruit but tended to improve as the number of hand pickings prior to machine harvest increased. Organoleptic evaluations of fruit puree from all harvesting treatments were rated acceptable.
Growth and Potassium Partitioning in Tomato1
Authors: Maynard D. N. , Lorenz O. A. , Magnifico V.
Published: October 2022

Solution and sand culture experiments were conducted with ‘Early Pak’, ‘VF 145’, and ‘UC 82’ tomatoes (Lycopersicon esculentum Mill.) to study the propensity for K stress shown by ‘VF 145’ plants. The measured parameters that may contribute to the expression of K stress in ‘VF 145’ are low root weight and K content, high shoot:root ratios, high fruit K content, and a low K efficiency ratio.
Growth Regulator Effects on Adventitious Root Formation in Leaf Bud Cuttings of Juvenile and Mature Ficus pumila1
Authors: Davies F. T. , Joiner J. N.
Published: October 2022

Adventitious root formation was stimulated with foliar application of indolebutyric acid (IBA) from 1000 to 1500 mg/liter for juvenile and 2000 to 3000 mg/liter for mature leaf bud cuttings of Ficus pumila L. IBA increased cambial activity, root initial formation, and primordia differentiation and elongation. IBA stimulated rooting when applied to juvenile cuttings at 3, 5, or 7 days after experiment initiation, but had no effect on mature cuttings when applied at day 15, the final treatment period. The interaction of IBA/gibberellic acid (GA3) did not affect early root development stages, but reduced root elongation and quality once primorida had differentiated. IBA/6-(benzylamino)-9-(2-tetrahydropyranyl)-9H-purine (PBA) inhibited rooting at early initiation stages.
Egy integratív tudományközi kutatás
Authors: Réthy Endréné
Published: October 2022

Gerebenné Várbíró Katalin, Reményi Tamás és Rosta Katalin (2021). Szenzoros információfeldolgozás, mozgás, nyelvi képesség. A Frostig-elven alapuló nevelési terápia elmélete és gyakorlata. Budapest: Gondolat Kiadó.
Imre Sándor alelnöksége az Országos Közoktatási Tanácsban II.
Authors: Donáth Péter
Published: October 2022

A Neveléstudomány két egymást követő számában megjelenő dokumentatív elbeszélő tanulmányunk az Országos Közoktatási Tanácsnak (OKT) egy a neveléstudományban, neveléstörténetben alig ismert időszakáról szolgál nagyrészt eddig ismeretlen vagy feledésbe merült forrásokkal. A második részben betekintést nyújtunk az OKT mindennapjaiba, azokba a témákba, melyekkel az utolsó háborús évek folyamán foglalkoztak: a polgári iskola új tantervével, a műszaki pályákra készülők gimnáziumi felkészítésével, az ötéves tanítóképzés kényszerű visszaállításának tervével, az óvodai neveléssel, a pedagógusok háborús helyzetről való tájékoztatásával, a leánylevente-vezetőképzéssel s a nemzetiségi oktatással. Képet kaphatunk az OKT tényleges pedagógiai vezetőjének, Imre Sándornak, valamint munkatársainak, Alszeghy Zsoltnak és Kovács Máténak erőfeszítéseiről az oktatás-nevelés körülményeinek védelme s az iskolák militarizálásának elhárítása érdekében.
A practical method for rehabilitation of stormwater collecting system by node flooding detection and regional hydraulic redesign: a case study of eastern Tehran metropolis
Authors: Barkhordari Soroush , Hamze Ghasabsarai Mojtaba , Garshasbi Meysam , Movahedinia Maryam , Hashemy Shahdany Seied Mehdy
Published: October 2022

This study investigates the effect of structural modification actions on the existing stormwater collecting system in Eastern Tehran to increase the hydraulic capacity and create suitable conditions for the passage of runoff in the critical points of the canal. First, the hydraulic conditions within the stormwater collecting system were simulated using the Stormwater Management Model (SWMM) model before/after the modification to investigate the rehabilitation results. Three critical locations along the main canal were recognized as the most vulnerable points. Then, based on field visits and brainstorming sessions, rehabilitation methods were presented, and three practical solutions, including canal deepening, canal widening, and their combination, were investigated for each. Then, local investigating based on the rehabilitation alternatives for each critical location was conducted using the HEC-RAS. Finally, the SWMM model was used again to evaluate the overall operational performance of the stormwater collecting system after the rehabilitation. The results revealed that it is necessary to implement two alternatives of deepening and widening to provide adequate transmission runoff capacity during rainfalls with various return periods. More specifically, the localized redesign of the eastern flood diversion canal had an acceptable improvement in reducing flooding problems so that for floods with a return period of 10 years, the number of node flooding dropped from 4 to 0, inundated areas from 17% to 0, and the overflow volume from (10–45) to 0. Moreover, the proposed local rehabilitation reduced the overflow volume from (30–65), (43–74), and (70–92) in the status quo to (4–12), (11–27), and (24–36) for rainfall with 25, 50, and 100-year return periods.
Inclusão de acadêmicos com deficiência na educação superior
Authors: Evêncio Kátia Maria de Moura , Falcão Giovana Maria Belém
Published: October 2022

Este escrito se refere a um recorte referente ao Estado da Questão desenvolvido entre setembro de 2020 a março de 2021, que compõe a pesquisa de doutoramento em educação, ainda em andamento, a qual investiga sobre os sentidos de inclusão produzidos por acadêmicos com autismo na educação superior. O objetivo deste artigo é mapear as pesquisas sobre inclusão de acadêmicos com deficiência na educação superior desenvolvidas no Brasil entre 2012 e 2020, à luz da teoria histórico-cultural. Por darmos ênfase às pesquisas de pós-graduação stricto sensu (mestrado e doutorado), a principal base de dados consultada foi a Biblioteca de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). O resultado do levantamento identificou um número reduzido de pesquisas que tiveram como base epistemológica a Psicologia Histórico-Cultural de Vigotski, o que reverbera na compreensão da inclusão enquanto fenômeno dialético histórico, social e culturalmente construído e, portanto, nos modos de pensar e fazer inclusivos.
Experiences of Primary Health Care Clients in Jordan: Qualitative Study
Authors: Alnawafleh Ahmad H. , Abu-Helalah Munir , Kayyali Ghadah
Published: October 2022

Objective:

This paper aims to understand the experiences of clients in utilising primary health care services in Jordan.

Design:

A qualitative study.

Methods:

Three focus group interviews with 22 clients who sought medical advice at primary health care clinics. The data were analysed thematically.

Results:

Findings were summarized in three main themes: 1) Clients’ experiences with general practitioners; 2) Causes of not seeking advice at clinics; 3) Clients’ perceptions of the physicians’ capabilities and professionalism. There was comfort and full access to primary health care (PHC) service, although clients were not satisfied sometimes. This is due to the absence, inadequate, and poor quality of the service. This may lead to several visits without getting the service required.

Conclusion:

Listening to the experiences of the clients and users of PHC identifies what works and what does not work in the service and improves the quality. Measuring the experiences of the users and the satisfaction of the clients is an important aspect of quality.
SELF-MANAGEMENT FOR SHAPING SLEEP BEHAVIOR AT NIGHT IN SCHIZOPHRENIA PATIENTS
Authors:   Psychology Bureau of Rumah Tabinda, Malang, Indonesia, Purnama Baiq
Published: October 2022

Background: Sleep disturbances in schizophrenia can be caused by abnormalities of the biological clock which are shown to be imbalanced in the sleep-wake cycle. In this case report, we report one of the patients with schizophrenia which already been hospitalized often. Objective: The purpose of this intervention is to improve the subject's adaptive behavior in the form of sleeping at night in a schizophrenia patient. Methods: This paper is a case report, which is already given applied therapy in self-management for shaping his sleep behavior at night which hopefully can help a patient with his problems. Assessments were carried out on the subject in the form of observation, interviews, giving Graphic tests, TAT, and WAIS. The results of the assessment stated that the subject could not manage his sleep schedule which interfered with his daily activities. The intervention given is using a behavioral approach with self-management methods which are arranged in 7 therapy sessions. Results: The patient can fulfill the target to be able to fall asleep well, this condition positively reduces his symptoms and agitative condition due to sleep problems. Conclusion: Self-management for shaping sleep behavior which combines psychodynamics and form of habitual condition from the patient can help to reduce their complaints and fulfill the target of remission. Keywords: self-management, sleep, behavior, schizophrenia.
Towards a Workshop Methodology for Involving Non-Expert Stakeholders in the Interactive Sound Design Process: Connecting Household Sounds and Energy Consumption Data
Authors: Seznec Yann , Pauletto Sandra
Published: October 2022

Sonic interaction design and sonification have the potential to provide new ways to display and interpret data and information. Data from a number of domains have been sonified: astronomy, finance, health, security, and many more. However in recent years, research in auditory displays has highlighted the importance of using participatory methods to include stakeholders, often users who are not experts in sound, in the design loop. This raises the question of how to discuss sound with participants who may not be familiar with it, and how to discuss links and relationships between sound and the specific domain which is the focus of the design. In this paper we propose a methodology for a participatory workshop with stakeholders that could be applied to a variety of domains. We describe how we have deployed this methodology in a workshop that aimed to explore attitudes to both sound and energy usage in the home environment, and discuss what can be gained from such an approach.
Investigating Real-Time Feedback of Energy Consumption and Emission Data Through Sonic Interaction Design
Authors: Madaghiele Vincenzo , Pauletto Sandra
Published: October 2022

As buildings become increasingly automated and energy efficient, the relative impact of occupants on the overall building carbon footprint is expected to increase. Research shows that by changing occupant behaviour energy savings between 5 and 15 % could be achieved. A commonly used device for energy-related behaviour change is the smart meter, a visual-based interface which provides users with data about energy consumption and emissions of their household. This paper approaches the problem from a Sonic Interaction Design point of view, with the aim of developing an alternative, sound-based design to provide feedback about some of the data usually accessed through smart meters. In this work, we experimented with sonic augmentation of a common household object, a door mat, in order to provide a non-intrusive everyday sonic interaction. The prototype that we built is an energy-aware sonic carpet that provides real-time feedback on home electricity consumption and emissions through sound. An experiment has been designed to evaluate the prototype from a user experience perspective, and to assess how users understand the chosen sonifications.
Sonification of TESS Data Validation Timeseries Files
Authors: Riber Adrian Garcia , Garcia Francisco Serradilla
Published: October 2022

In August 2022, the Transiting Exoplanet Survey Satelite (TESS) will start its fifth year of exploration having observed and analyzed more than a million stars in the search of extrasolar planets around both celestial hemispheres. At this time, with 5,767 declared TESS objects of interest (TOI), the total number of confrmed planets that appear in peer-reviewed journals exceeds 220. This article describes the prototype design and domain conversion strategies used for the sonification of Data Validation Time-series (DVT) fles from TESS mission. Focused on 132 examples of publicly available lightcurves from stars hosting at least one planet confrmed during the first four years of TESS observations, the resulting proposal allows the multi-modal and multi-channel automatic interactive aural exploration of astronomical variables, generating sequences of complete soundscapes from target variables stored in each DVT file, which can be controlled in terms of complexity and balance. Aesthetics and inspiring aspects of Sonification are also open for discussion.
Tōkyō Kion-on: Query-Based Generative Sonification of Atmospheric Data
Authors: Kalonaris Stefano
Published: October 2022

Amid growing environmental concerns, interactive displays of data constitute an important tool for exploring and understanding the impact of climate change on the planet’s ecosystemic integrity. This paper presents Tōkyō kion-on, a query-based sonification model of Tokyo’s air temperature from 1876 to 2021. The system uses a recurrent neural network architecture known as LSTM with attention trained on a small dataset of Japanese melodies and conditioned upon said atmospheric data. After describing the model’s implementation, a brief comparative illustration of the musical results is presented, along with a discussion on how the exposed hyper-parameters can promote active and non-linear exploration of the data.
Determinan Nilai Perusahaan pada Sektor Perusahaan Properti dan Real Estate di Indeks Saham Syariah Indonesia
Authors: Mahendra Weri , Sahibuddin Siti Ainunnisa
Published: October 2022

Abstrak: Determinan Nilai Perusahaan pada Sektor Perusahaan Properti dan Real Estate di Indeks Saham Syariah Indonesia. Studi ini memiliki tujuan untuk mengetahui pengaruh dari profitabilitas, leverage, dan likuiditas terhadap nilai dari sebuah perusahaan. Studi ini dilaksanakan pada perusahaan properti dan real estate yang terdaftar di Indeks Saham Syariah Indonesia (ISSI) tahun 2016-2020. Data yang digunakan pada studi ini yaitu data sekunder yang berasal dari laporan tahunan dan laporan berkelanjutan perusahaan dari situs resmi BEI (Bursa Efek Indonesia) dan dari situs perusahaan. Metode penelitian yang dipakai menggunakan teknik analisis regresi logit. Sampel yang diperoleh sebanyak 105 observasi penelitian dengan menggunakan metode purposive sampling. Hasil penelitian ini dapat disimpulkan bahwa dengan memasukkan nilai rata-rata dari masing-masing variabel bebas maka dimungkinkan perusahaan dapat dikatakan baik, dengan persentase 38%. Pada pengujian simultan variabel dari leverage, likuiditas dan profitabilitas mempunyai pengaruh yang signifikan terhadap nilai suatu perusahaan. Hasil pengujian pada uji parsial, profitabilitas dan leverage mempunyai pengaruh secara positif signifikan terhadap nilai suatu perusahaan, sedangkan likuiditas tidak memiliki pengaruh signifikan terhadap nilai perusahaan.Kata kunci: Economic Value Added, Profitabilitas, Likuiditas, LeverageAbstract: Determinants of Company Value in Property and Real Estate Sector Companies at Indonesian Sharia Stock Index. This study aims to determine the effect of profitability, leverage, and liquidity on the value of a company. This research was conducted on property and real estate companies listed on the Indonesian Sharia Stock Index (ISSI) in 2016-2020. The data used in this study is secondary data derived from the annual report and company sustainability report from the official website of the IDX (Indonesian Stock Exchange) and from the company's website. The research method used is logit regression analysis technique. The sample obtained is 105 research observations using purposive sampling method. The results of this study can be concluded that by including the average value of each independent variable then the possibility of the company can be said to be good, with a percentage of 38%. In simultaneous testing, the variables of leverage, liquidity and profitability have a significant effect on firm value. The test results on the partial test, profitability and leverage have a significant positive effect on firm value, while liquidity has no significant effect on firm value.Keywords: Economic Value Added, Profitability, Liquidity, Leverage
The Value of Financial and Non-Financial Information towards Non-profit Organisations
Authors: Abdullah Hadi Hasnatulsyakhira , Bakar Ahmad Naqiyuddin , Mohd Noor Nurul Hidayana , Ashfahany Afief El
Published: October 2022

The role of nonprofit organizations has been acknowledged.  They are the providers of services that the government cannot handle alone. Accountability is an obligation to conduct and account for the company's performance. Information disclosure is one of the mechanisms used to be accountable to their stakeholders, which are financial and non-financial information. This study explored the importance of financial and non-financial information in NPOs and the Internet as the medium for disclosing information to stakeholders. This study applied a qualitative research design using content analysis. This research found that both types of information are crucial to NPOs.
Keywords: Information disclosure; Nonprofit organization; Financial information; Non-financial information
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under the responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians), and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i21.3693
Digitalisation of Heritage Conservation Documents of Rumah Uda Manap
Authors: Hamzah Nur Rafida , Mat So'od Noor Fatehah , Abdul Aziz Zirwatul Amani , Hinchman Mark
Published: October 2022

Pure's aspiration to preserve traditional Malay legacy deserves respect. However, heritage preservation and conservation are complex and costly. Reconstructing buildings through digitalization to document the heritage conservation virtually would be the solution to save costs and time. The study was conducted on Rumah Uda Manap (RUM) in Kuang, Selangor. This research aim to digitalize the documents of RUM as part of conservation effort of traditional houses. The onsite observation and virtual measurement is applied as the data collection method. This study has demonstrated that digital measured drawing has opportunities that can be explored as part of the future conservation effort.
Traditional Malay House in Negeri Sembilan: Cultural influence in design and construction
Authors: Azman Nor Syawallina , Mazlan Ida Marlina , Sujak Ilyana , Mat So'od Noor Fatehah , Wallen Lawrence
Published: October 2022

The architecture of the Traditional Malay houses reflects the physical environment to portray the family and community manifestation of the cultures and behaviours. This research attempts to discover the cultural manifestation that has affected the design and construction. The case study method is applied, specifically focusing on a case study of Rumah Telapak Ibu Soko, Tanah Datar 48, located in Kuala Pilah, Malaysia, consisting of on-site physical measurement and observation and an interview with the owner. The findings are part of explored social values and the impact of cultural influence on design and construction.
Climate-induced migrations in Mesoamerica with a gender perspective
Authors: Oswald Spring Ursula
Published: October 2022

El objetivo es analizar la migración climática desde Mesoamérica, integrando factores sistémicos de pobreza, pandemia, desastres ambientales, dilema de supervivencia, inseguridad y violencia dentro de una perspectiva de género. Desastres climáticos han aumentado los riesgos sistémicos y generado procesos en cascada por insuficientes políticas gubernamentales de prevención, mitigación y adaptación. Adicionalmente, políticas norteamericanas anti-migrantes, una militarización de las fronteras y el crimen organizado han aumentado la violencia regional, forzando a personas pobres a emigrar dentro de caravanas. Durante estos trayectos, las mujeres, por sus apoyos, han alcanzado mayor equidad, justicia y capacitación en condiciones altamente adversas. Estos aprendizajes han generado reconocimiento y normas culturales más incluyentes, que fueron aplicados aun cuando los migrantes fueron repatriados hacia sus países, donde han promovido una economía del cuidado. Esta permitió adaptarse a desastres climáticos y participar en la política local, donde se han promovido prácticas productivas sustentables que han mejorado la economía e igualdad en la sociedad. Están superado pobreza extrema y patrones patriarcales violento-discriminatorios al mejorar la economía familiar y proteger a la comunidad ante impactos climáticos crecientemente más severos.
Fast Healthcare Interoperability Resources for Inpatient Deterioration Detection With Time-Series Vital Signs: Design and Implementation Study
Authors: Tseng Tzu-Wei , Su Chang-Fu , Lai Feipei
Published: October 2022

Background

Vital signs have been widely adopted in in-hospital cardiac arrest (IHCA) assessment, which plays an important role in inpatient deterioration detection. As the number of early warning systems and artificial intelligence applications increases, health care information exchange and interoperability are becoming more complex and difficult. Although Health Level 7 Fast Healthcare Interoperability Resources (FHIR) have already developed a vital signs profile, it is not sufficient to support IHCA applications or machine learning–based models.

Objective

In this paper, for IHCA instances with vital signs, we define a new implementation guide that includes data mapping, a system architecture, a workflow, and FHIR applications.

Methods

We interviewed 10 experts regarding health care system integration and defined an implementation guide. We then developed the FHIR Extract Transform Load to map data to FHIR resources. We also integrated an early warning system and machine learning pipeline.

Results

The study data set includes electronic health records of adult inpatients who visited the En-Chu-Kong hospital. Medical staff regularly measured these vital signs at least 2 to 3 times per day during the day, night, and early morning. We used pseudonymization to protect patient privacy. Then, we converted the vital signs to FHIR observations in the JSON format using the FHIR Extract Transform Load application. The measured vital signs include systolic blood pressure, diastolic blood pressure, heart rate, respiratory rate, and body temperature. According to clinical requirements, we also extracted the electronic health record information to the FHIR server. Finally, we integrated an early warning system and machine learning pipeline using the FHIR RESTful application programming interface.

Conclusions

We successfully demonstrated a process that standardizes health care information for inpatient deterioration detection using vital signs. Based on the FHIR definition, we also provided an implementation guide that includes data mapping, an integration process, and IHCA assessment using vital signs. We also proposed a clarifying system architecture and possible workflows. Based on FHIR, we integrated the 3 different systems in 1 dashboard system, which can effectively solve the complexity of the system in the medical staff workflow.
Perception of People With Diabetes Regarding Blood Glucose Meters That Support Achievement of Self-Management Goals: Online evaluation in United States, Canada, France, and Germany. (Preprint)
Authors: Beatson Christie , Hurrell Graham , Holt Elizabeth
Published: October 2022

BACKGROUND

Blood glucose meters remain an effective tool for glucose monitoring, but not all meters provide the same level of insight beyond numerical glucose results.

OBJECTIVE

To investigate the perceptions of people with diabetes (PWDs) of four meters and how they support the achievement of self-management goals recommended by diabetes clinical practice guidelines.

METHODS

1192 PWDs from four countries reviewed features of four meters using unbranded interactive webpages and determined which meter ranked highest in terms of meeting glucose management goals in various clinical scenarios.

RESULTS

Meter A (OneTouch Reflect) ranked highest (p=<0.05) in all scenarios vs. meters B, C, or D. Participants with type 2 diabetes ranked meter A slightly higher than participants with type 1 diabetes. Results were not statistically different among participants from the 4 countries.

CONCLUSIONS

PWDs had the strongest preference for a meter providing insights, encouragement, and guidance to support achievement of glucose self-management goals.
A protocol to evaluate a clinical decision support tool using natural language processing to screen hospitalized adults for unhealthy substance use in a quasi-experimental design (Preprint)
Authors: Joyce Cara , Markossian Talar W. , Nikolaides Jenna , Ramsey Elisabeth , Thompson Hale M. , Rojas Juan C. , Sharma Brihat , Dligach Dmitriy , Oguss Madeline K. , Cooper Richard S. , Afshar Majid
Published: October 2022

BACKGROUND

Automated and data-driven methods for screening using natural language processing (NLP) and machine learning may replace resource-intensive manual approaches in usual care of patients hospitalized with conditions related to unhealthy substance use. Rigorous evaluation of tools that use artificial intelligence (AI) is necessary to demonstrate effectiveness before system-wide implementation.

OBJECTIVE

To provide a study protocol to evaluate health outcomes and cost-benefit of an AI-driven automated screener compared to manual human screening for unhealthy substance use.

METHODS

A pre-post design to evaluate 12 months of manual screening followed by 12 months of automated screening across surgical and medical wards in a single medical center. Effectiveness in terms of patient outcomes will be determined by non-inferior rates of interventions (brief intervention/motivational interviewing, medication assisted treatment, naloxone dispensing, referral to outpatient care) in the post-period by a substance use intervention team compared to pre-period. A separate analysis will be performed to assess the cost-benefit to the health system of using automated screening.

RESULTS

A natural language processing tool to use routinely collected data in the electronic health record was previously validated for diagnostic accuracy in a retrospective study for screening unhealthy substance use. Our next step is a non-inferiority design incorporated into a research protocol for clinical implementation with prospective evaluation of clinical effectiveness in a large health system. The study is approved by the Institutional Review Board and registered at clinicaltrials.gov with a plan for implementation beginning in September 2022.

CONCLUSIONS

The use of augmented intelligence for clinical decision support is growing with an increasing number of artificial intelligence tools. We provide a research protocol for prospective evaluation of an automated NLP system for screening unhealthy substance use using a non-inferiority design to demonstrate comprehensive screening that may be as effective as manual screening but less costly via automated solutions.

CLINICALTRIAL

ClinicalTrials.gov NCT03833804
Potential of marine sponge Jaspis sp.‐associated bacteria as an antimicrobial producer in Enggano Island
Authors: Sipriyadi Sipriyadi , Nurfahmi Riziq Ilham , Cahlia Uci , Wibowo Risky Hadi , Darwis Welly , Nugraheni Enny
Published: October 2022

Sponges, a group of marine multicellular animals with a porous body structure, show potential for the production of bioactive compounds. Sponge‐associated bacteria are an alternative antimicrobial producer due to their high content of bioactive compounds. This study aimed to identify the highest‐potential antimicrobial‐producing bacteria isolate associated with Jaspis sp. sponges from Enggano island. The isolated bacteria were screened for antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans using cultures, supernatants, pellets, and crude extracts. The study also conducted genetic identification to determine the identity of the isolate with the greatest potency and its closest relationship using the 16S rRNA gene. The antimicrobial activity was determined by monitoring and measuring the diameter of the formed clear zones. The results of the observations of morphological characteristics revealed nine isolates from Jaspis sp. that each consisting of 6 JABS isolates and 3 JABB isolates. Based on isolates that had antimicrobial activity, JABS6 isolates had the best antimicrobial activity, with the diameter of inhibition zones of 24.7, 8.2, 4.6, and 33.7 mm for E. coli, P. aeruginosa, S. aureus and C. albicans, respectively. The genome sequencing of the JABS6 isolate confirmed that it was identical to Bacillus thuringiensis strain USS‐CAP‐1. The study concludes that this finding shows promise for the further development of future antimicrobial agents.
Establishment of transgenic potato cultivar IPB CP1 plants containing gene encoding for superoxide dismutase to increase the abiotic stress tolerance
Authors: Musawira Musawira , Suharsono Suharsono , Miftahudin Miftahudin , Tjahjoleksono Aris
Published: October 2022

Potato ( Solanum tuberosum L.) cultivar IPB CP1 is suitable as a raw material for the potato chip industry. Potato plants are sensitive to various abiotic stresses such as drought, aluminium and salinity, which induce reactive oxygen species (ROS). ROS is very toxic to plant cells. Superoxide dismutase (SOD) is one of the enzymes that catalyse ROS to H2O2 and O2. This study aimed to establish transgenic potato cv. IPB CP1 plants containing the MmCuZn‐SOD gene that are tolerant to various abiotic stresses. Genetic transformation using internodes without buds as explants produced putative transgenic potato with a transformation efficiency of 51.25% and a regeneration efficiency of 38.87%. Integration analysis of the MmCuZn‐SOD transgene in putative transgenic plants by polymerase chain reaction (PCR) with a set of specific primers showed that eight plants contained the MmCuZn‐SOD gene under the control of the 35S CaMV promoter. In vitro salinity stress, aluminium stress, and drought stress assays showed that transgenic plants had a higher number of roots and total root length than non‐transgenic ones. These results indicate that transgenic potato cv. IPB CP1 plants are more tolerant to abiotic stresses than non‐transgenic ones.
DEVELOPMENT AND VALIDATION OF THE RP-HPLC METHOD FOR ESTIMATION OF CILNIDIPINE IN RAT PLASMA
Authors: JAISWAL RAMANKIT , WADETWAR RITA
Published: October 2022

Objective: A simple, precise, accurate, robust, and reliable RP-HPLC technique for detecting cilnidipine in Wistar rat plasma was developed and validated.
Methods: The chromatographic separation was performed using the C-18 reverse phase column Oyster BDS Premium C18 column (4.6 × 150 mm, 5 µm particle size). The flow rate was set to 1.2 ml/min, and the chromatogram was recorded at 240 nm. The proposed method was validated in compliance with the International Conference on Harmonization (ICH) guidelines.
Results: The calibration curves plotted were found to be linear over the concentration range of 40-200 ng/ml in Wistar rat plasma, with a regression coefficient of R2>0.999, suggesting that the linearity was within limits. The LOD and LOQ of the present method were found to be 2.184 and 4.518 ng/ml, respectively. Drug extraction recoveries from Wistar rat plasma were found to be >98%.
Conclusion: Using Wistar rat plasma, a simple, fast, specific, accurate, and precise analytical approach was developed and validated. The technique was validated according to the ICH guidelines. The obtained results show that the suggested technique can be simply and effectively utilized for routine cilnidipine analysis in Wistar rat plasma.
EFECTOS DE LA PANDEMIA COVID-19 EN LA PRODUCCIÓN ESTATAL DE MÉXICO
Authors: Díaz Carreño Miguel Ángel , Mejía Reyes Pablo , Rendón Rojas Liliana
Published: October 2022

RESUMEN
Este artículo presenta un análisis de la caída de la producción de los estados de México en el segundo trimestre de 2020 como consecuencia de la pandemia de COVID-19. Estimamos modelos econométricos de corte transversal (ante la ausencia de efectos espaciales) y encontramos que las variables asociadas al contexto internacional, como las remesas, el grado de integración internacional y el sector básico, no tienen efectos estadísticamente significativos en la profunda contracción de la producción estatal, en tanto que la producción manufacturera, en particular de la bienes durables, las actividades turísticas y de esparcimiento resultaron significativas en su explicación.
 
EFFECTS OF THE COVID-19 PANDEMIC ON MEXICO’S STATES PRODUCTION
ABSTRACT
This paper develops an analysis of the deep production contraction of Mexico’s 32 states in the second quarter of 2020 as a consequence of the COVID-19 pandemic. Cross-section econometric models are estimated (in the absence of spatial effects); the main results suggest that variables associated to the international context, such as remittances, degree of international integration and basic tradeable goods production do not have statistically significant effects on the drop of production, while manufacturing production, particularly that of durable goods, and touristic and leisure activities are significant in explaining it.
A Multi-Criteria Decision-Making Approach for Building Maintenance Strategy Selection using Choosing by Advantages
Authors: Besiktepe Deniz , Ozbek Mehmet E. , Atadero Rebecca A.
Published: October 2022

Maintenance strategy selection is a challenging process in building maintenance and facility management (FM). In addition to financial constraints, multiple criteria need to be considered to increase the efficiency of maintenance decisions. The purpose of this study is to demonstrate a structured and systematic decision-making approach in building maintenance and FM. For this purpose, a new generation multi-criteria decision-making method, Choosing by Advantages (CBA), is utilized. CBA allows for the consideration of multiple criteria and their advantages. CBA identifies the most-value generating alternative without initially considering cost. Cost, in turn, is defined as a constraint and included later in the process after determining other advantages are established. In addition, CBA facilitates group decision-making. The implementation of the CBA-based decision-making framework is presented using a hypothetical case study. The proposed systematic decision-making approach, which aids in improving the outcome of decisions, is promising in decision-making as well as resource allocation for maintenance needs in FM.
Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid–Induced Rat β-Cell Proliferation
Authors: Vivoli Alexis , Ghislain Julien , Filali-Mouhim Ali , Angeles Zuraya Elisa , Castell Anne-Laure , Sladek Robert , Poitout Vincent
Published: October 2022

The functional mass of insulin-secreting pancreatic β-cells expands to maintain glucose homeostasis in the face of nutrient excess, in part via replication of existing β-cells. Type 2 diabetes appears when these compensatory mechanisms fail. Nutrients including glucose and fatty acids are important contributors to the β-cell compensatory response, but their underlying mechanisms of action remain poorly understood. We investigated the transcriptional mechanisms of β-cell proliferation in response to fatty acids. Isolated rat islets were exposed to 16.7 mmol/L glucose with or without 0.5 mmol/L oleate (C18:1) or palmitate (C16:0) for 48 h. The islet transcriptome was assessed by single-cell RNA sequencing. β-Cell proliferation was measured by flow cytometry. Unsupervised clustering of pooled β-cells identified different subclusters, including proliferating β-cells. β-Cell proliferation increased in response to oleate but not palmitate. Both fatty acids enhanced the expression of genes involved in energy metabolism and mitochondrial activity. Comparison of proliferating versus nonproliferating β-cells and pseudotime ordering suggested the involvement of reactive oxygen species (ROS) and peroxiredoxin signaling. Accordingly, N-acetyl cysteine and the peroxiredoxin inhibitor conoidin A both blocked oleate-induced β-cell proliferation. Our study reveals a key role for ROS signaling through peroxiredoxin activation in oleate-induced β-cell proliferation.
Gut Microbiota Regulate Pancreatic Growth, Exocrine Function and Gut Hormones
Authors: Girdhar Khyati , Soto Marion , Huang Qian , Orliaguet Lucie , Cederquist Carly , Sundaresh Bharathi , Hu Jiang , Figura Maximilian , Raisingani Amol , Canfora Emanuel E. , Dirice Ercument , Fujisaka Shiho , Goossens Gijs H. , Blaak Ellen E. , Kulkarni Rohit N. , Kahn C. Ronald , Altindis Emrah
Published: October 2022

Growing evidence indicates an important link
between gut microbiota, obesity, and metabolic syndrome. Alterations in
exocrine pancreatic function are also widely present in patients with diabetes
and obesity. To examine this interaction, C57BL/6J mice were fed either a chow
diet, high-fat diet (HFD) or HFD plus oral vancomycin or metronidazole to
modify the gut microbiome. HFD alone leads to a 40% increase in pancreas
weight, decreased glucagon-like peptide-1 and peptide YY levels, and increased
glucose-dependent insulinotropic peptide in the plasma. Quantitative
proteomics identified 138 host proteins
in fecal samples of these mice, of which 32 were significantly changed by HFD.
The most significant of these were the pancreatic enzymes. These changes in amylase
and elastase were reversed by antibiotic treatment. These alterations could be
reproduced by transferring gut microbiota from donor C57BL/6J mice to
germ-free. By contrast, antibiotics had no effect on pancreatic size or
exocrine function in C57BL/6J mice fed a chow diet. Further,
one week vancomycin administration significantly increased amylase and elastase
levels in obese prediabetic men. Thus, the alterations in gut microbiota in
obesity can alter pancreatic growth, exocrine function and gut endocrine
function, and may contribute to the alterations observed in patients with
obesity and diabetes.
A invenção das mudanças curriculares para a disciplina biologia em currículos estaduais (1992-2009)
Authors: Rodrigues Diego Adaylano Monteiro , Carneiro Claudia Christina Bravo e Sá
Published: October 2022

O objetivo deste trabalho é compreender os processos de produção de três currículos oficiais estaduais cearenses para a disciplina Biologia, formulados em 1992, 2000 e 2009. Dialoga com pressupostos das teorias críticas do currículo e da história das disciplinas escolares. Trata-se de uma pesquisa qualitativa, que relaciona fontes documentais e fontes orais com entrevistas a autores e coordenadores dos currículos oficiais. A pesquisa foi subsidiada pela Análise Textual Discursiva (ATD). Identificou-se participação crescente de professores de escolas públicas na construção dos currículos estaduais. Em alguns casos, omitiram-se nomes de docentes ou houve tensões na formulação das propostas, devido a distintos pensamentos curriculares e relações de poder dos subgrupos que produziram os currículos.
Desafios da entrada na carreira docente na educação física sob a análise de professores formadores da universidade
Authors: Rufino Luiz Gustavo Bonatto , Souza Neto Samuel de
Published: October 2022

Este estudo objetivou analisar as representações de sete professores de universidades públicas do estado de São Paulo com relação aos principais desafios para a inserção profissional de professores de Educação Física, no início de carreira, na escola. As entrevistas foram submetidas à Análise de Conteúdo, resultando em duas categorias: “Considerações acerca da falta de acompanhamento de egressos na inserção profissional como professor de Educação Física” e “Perspectivas acerca da discrepância entre formação e prática profissional para o professor iniciante na Educação Física”. Os formadores reconheceram o distanciamento entre formação e inserção profissional, o que incide de modo veemente nos professores iniciantes. Políticas de acompanhamento de inserção de professores são necessárias, o que se apresenta como desafio para universidades, escolas e políticas públicas na atualidade.