European recommendations for short-term surveillance of health problems in childhood, adolescent and young adult cancer survivors from the end of treatment to 5 years after diagnosis: a PanCare guideline
Authors: de Beijer Ismay A. E. , Skinner Roderick , Haupt Riccardo , Grabow Desiree , Bardi Edit , Beccaria Andrea , Nieto Adela Cañete , Essiaf Samira , Filbert Anna-Liesa , Gsell Hannah , Kienesberger Anita , Langer Thorsten , McColgan Patricia , Muraca Monica , Rascon Jelena , Tallone Ramona , Tomasikova Zuzana , Uyttebroeck Anne , Kremer Leontien C. M. , van der Pal Helena J. H. , Mulder Renée L. ,   on behalf of the PanCareSurPass consortium, Grabow Desiree , Filbert Anna-Liesa , Niehoff Dorothea , Walz Diana , Erdmann Friederike , Spix Claudia , Haupt Riccardo , Muraca Monica , Lightwood Simone , Bagnasco Francesca , Cavalca Giacomo , Oberti Sara , Nicolas Brigitte , Ladenstein Ruth , Bardi Edit , Düster Vanessa , Uyttebroeck Anne , van Helvoirt Maria , Lemiere Jurgen , Renard Marleen , Michiels An , Langer Thorsten , Kock-Schoppenhauer Ann-Kristin , Hildebrand Lea , Jahnke Anke Neumann Anne-Katrin , Rascon Jelena , Trinkūnas Justas , Ciesiūnienė Audronė , Ragauskas Paulius , Nieto Adela Cañete , Guill Julia Balaguer , Alcañiz Maria Teresa Tormo , Galan Antonio Orduña , Palau Marisa Correcher , Beltrán Lucas Cervero , Tamarit Vicente Pons , Saraceno Davide , Berti Alessandra , Contino Carlo , Thomopulos Nikos , Stabile Giulia , Tomassi Maria Franca , Zamberlan Igor , Nichel Barbara , Schreier Günter , Hayn Dieter , Kreiner Karl , Beyer Stefan , Chronaki Catherine , Cangioli Giorgio , Charalambous Eliana , Degelsegger-Márquez Alexander , Gredinger Gerald , Trunner Kathrin , Trauner Florian , Laschkolnig Anja , Kremer Leontien , van der Pal Heleen , Pluijm Saskia , van den Oever Selina , de Beijer Ismay , Trollip Jessica , Hardijzer Emma , van der Pal Heleen , Hartogh Jaap den , Dorsthorst Jeroen te , Essiaf Samira , Sciberras William , Kienesberger Anita , Gsell Hannah , Schneider Carina , Tomasikova Zuzana 
Published: December 2023

Purpose

Childhood, adolescent and young adult (CAYA) cancer survivors require ongoing surveillance for health problems from the end of cancer treatment throughout their lives. There is a lack of evidence-based guidelines on optimal surveillance strategies for the period from the end of treatment to 5 years after diagnosis. We aimed to address this gap by developing recommendations for short-term surveillance of health problems based on existing long-term follow-up (LTFU) care guidelines.

Methods

The guideline working group, consisting of healthcare professionals, parents and survivor representatives from 10 countries, worked together to identify relevant health problems that may occur in survivors between the end of treatment and 5 years after diagnosis and to develop recommendations for short-term surveillance of health problems. The recommendations were drawn from existing LTFU guidelines and adapted where necessary based on clinical expertise.

Results

The working group developed 44 recommendations for short-term surveillance of health problems, which were divided into four categories based on the level of surveillance required: awareness only (n = 11), awareness, history and/or physical examination without surveillance test (n = 15), awareness, history and/or physical examination with potential surveillance test (n = 1) and awareness, history and/or physical examination with surveillance test (n = 17).

Conclusion

The development of a guideline for short-term surveillance of health problems fills a critical gap in survivorship care for CAYA cancer survivors, providing much-needed support immediately after treatment up to 5 years after diagnosis.

Implications for Cancer Survivors.

This guideline will support healthcare professionals to provide appropriate follow-up care and improve the quality of life of CAYA cancer survivors.