bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential roles of microRNA-1 and microRNA-133 in cardiovascular disease
Authors: Song Zhipeng , Gao Rui , Yan Bo
Published: April 2020

Cardiovascular disease is still the main cause of morbidity and mortality worldwide. Currently, the frontier of research into cardiovascular disease is the field of non-coding RNA. In this review, information was collected on the use of micro-RNAs as non-invasive biomarkers and their role in pathophysiological processes and therapeutic applications. In the case of microRNA-1 and microRNA-133, the roles and regulatory mechanisms of them are reviewed for arrhythmia, myocardial infarction, diabetic cardiomyopathy, myocardial hypertrophy, cardiomyocyte differentiation, and cell reprogramming. It was observed that microRNA-1 and microRNA-133 do not exist independently, but are two co-transcriptional and cooperative regulatory factors. They have diagnostic value as biomarkers, but also have the potential as therapeutic targets such as for antiarrhythmia and cardiac reprogramming.
Important topics for fostering research integrity by research performing and research funding organizations – A Delphi consensus study
Authors: Labib Krishma , Roje Rea , Bouter Lex , Widdershoven Guy , Evans Natalie , Marusic Ana , Mokkink Lidwine , Tijdink Joeri K.
Published: April 2020

To foster research integrity (RI), it is necessary to address the institutional and system-of-science factors that influence researchers’ behavior. Consequently, research performing and research funding organizations (RPOs and RFOs) could develop comprehensive RI policies outlining the concrete steps they will take to foster RI. So far, there is no consensus on which topics are important to address in RI policies. Therefore, we conducted a three round Delphi survey study to explore which RI topics to address in institutional RI policies by seeking consensus from research policy experts and institutional leaders. A total of 68 RPO and 52 RFO experts, representing different disciplines, countries and genders, completed one, two or all rounds of the study. There was consensus among the experts on the importance of 12 RI topics for RPOs and 11 for RFOs. The topics that ranked highest for RPOs concerned education and training, supervision and mentoring, dealing with RI breaches, and supporting a responsible research process (e.g. through quality assurance). The highest ranked RFO topics concerned dealing with breaches of RI, conflicts of interest, and setting expectations on RPOs (e.g. about educating researchers about RI). Together with the research policy experts and institutional leaders, we developed a comprehensive overview of topics important for inclusion in the RI policies of RPOs and RFOs. The topics reflect preference for a preventative approach to RI, coupled with procedures for dealing with RI breaches. RPOs and RFOs should address each of these topics in order to support researchers in conducting responsible research.
ARTIKEL PENGENALAN SISTEM INFORMASI
Authors: FITRIANI WITA
Published: April 2020

abstratcAudit Sistem Informasi (Informatin System Audit) atau EDP Audit (Electronic Data Processing Audit) atau computer audit adalah proses pengumpulan data dan pengevaluasian bukti-bukti untuk menentukan apakah suatu sistem aplikasi komputerisasi telah menetapkan dan menerapkan sistem pengendalian internal yang memadai, semua aktiva dilindungi dengan baik atau disalahgunakan serta terjaminnya integritas data, keandalan serta efektifitas dan efesiensi penyelenggaraan sistem informasi berbasis komputer (Ron Weber 1999:10).Kata kunci: pengenalan audit sistem informasi
Discrete Network Design Problem
Authors: Rahimi Alireza
Published: April 2020

The network design problem aims to minimize the travelers’ total cost under budget restrictions. This research provides a framework to incorporate variable demand assignment in the discrete network design problem. The findings emphasized the impact of considering variable demand in discrete network design problem.
Do Survey Estimates of the Public’s Compliance with COVID-19 Regulations Suffer from Social Desirability Bias?
Authors: Larsen Martin Vinæs , Petersen Michael Bang , Nyrup Jacob
Published: April 2020

The COVID-19 pandemic has led governments to instate a large number of restrictions on and recommendations for citizens’ behavior. One of our best tools for measuring compliance with these strictures are nationally representative surveys that ask citizens to self-report their behavior. But if respondents’ avoid disclosing socially undesirable behaviors, such as not complying with government strictures in a public health crisis, estimates of compliance will be biased upwards. To assess the magnitude of this problem, this study compares measures of compliance from direct questions to those estimated from list-experiments - a response technique that allows respondents to report illicit behaviors without individual-level detection. Implementing the list-experiment in two separate surveys of Danish citizens (n>5,000), we find no evidence that citizens under-report non-compliant behavior. We therefore conclude that survey estimates of compliance with COVID-19 regulations do not suffer from social desirability bias
Síndrome de Wolff Parkinson White en paciente gestante
Authors: Astudillo Taco Edwin Javier , Aguayo Eldredge Carlos , Ayala Casa Cristian , Caguano Caza Willian , Cisnero Chaw Diana , Pavon Burbano Ricardo , Pumarica Tipan Jordy
Published: April 2020

Introducción: El embarazo es un estado fisiológico, de varios cambios anatómicos, hormonales, hemodinámicos y electrofisiológicos. El síndrome de Wolff-Parkinson-White,  es una anomalía congénita en el sistema de conducción eléctrica del corazón, con cambios sugestivos de preexcitación en el electrocardiograma.objetivos de la OMS  en reducir la morbimortalidad  materno neonatal.

Objetivo: Describir el caso clínico de una paciente gestante con patología cardiaca compatible con Síndrome de Wolff Parkinson White  en tratamiento con fármaco beta bloqueador.

Material y métodos: Estudio descriptivo retrospectivo, presentación de caso clínico.

Resultados: Paciente sexo femenina de 17 años, con antecedente de Síndrome de Wolff Parkinson White (WPW) diagnosticado hace 2 años 7 meses en tratamiento con Carvedilol 6,25mg una vez al día con control periódico con cardiólogo. Asiste  a control subsecuente de embarazo (24 semanas de gestación) con resultado de exámenes de laboratorio  dentro de parámetros normales,  refiere palpitaciones, acompañadas de sudoración, astenia y vértigo  de una hora de evolución para lo cual se automedica 6,25 mg de carvedilol adicional a la dosis habitual sin mejoría. Al momento Score MAMA 3 a expensas de la frecuencia cardiaca (200-220 lpm) por lo que  se la traslada con toda las medidas primarias a unidad de mayor capacidad resolutiva para estabilización y valoración por cardiólogo, el cual suspende medicación habitual e inicia Atenolol 50 mg una vez al día hasta finalización del embarazo, explica posibles efectos adversos fetales y continuar con controles prenatales y por patología de base con cardiología.

Conclusiones: La evidencia científica sobre el uso de betabloqueantes y su seguridad durante el embarazo, continúa siendo motivo de estudio y controversia, por lo que en los próximos años se necesitará de nuevas investigaciones que permitan esclarecer más este aspecto.
The Effects of Contextual Learning and Teacher's Work Spirit on Learning Motivation and Its Impact on Affective Learning Outcomes
Authors: Naziah Risyatun , Caska Caska , Nas Syakdanur , Indrawati Henny
Published: April 2020

The goal of achieving student learning outcomes is not entirely only values in numbers or cognitive learning outcomes. But it also attaches great importance to the affective learning outcomes shown in attitudes or behavior. This study aims to analyze the effect of contextual learning approaches and teacher morale on learning motivation and its impact on student affective learning outcomes. The population in this study were 728 grade 8 students of SMP Negeri 20 and SMP Negeri 23 in Tampan. With the cluster random sampling technique a sample of 155 students was obtained. Data collection used a questionnaire then the data were analyzed by path analysis. The results found that contextual learning approaches have an influence on student motivation, the experience of working with friends while learning has an effect on student motivation and learning behavior, a positive effect on behavior is shown in attitudes manifested in affective domain learning outcomes. The work spirit of the teacher contributes to student affective learning outcomes, high teacher enthusiasm and the teacher's ability have an effect on student motivation to positively impact student affective learning outcomes.
Selbstgestaltung in aller Seelenruhe. Lebenskunst in Christoph Martin WielandsAristipp und einige seiner Zeitgenossen(1800/1801)
Authors: Schiefelbein Ulrike
Published: April 2020

Wieland’s epistolary novel Aristipp presents a process of self-formation and self-regulation through writing and reading. The article begins by presenting the main characters’ modes of life as gender-specific paradigms for an independent life. The ancient ars vivendi is central to these modes of life in that it represents the practice of self-formation based upon the characters’ recognition of the possibilities of social influence. Wieland represents writing and reading as the key ways of training oneself in this art of living. The characters form themselves through monologue and dialogue. At the same time, the genre of the epistolary novel serves to emphasize the autopoetic dimension of speech within the process of self-creation, as well as the discursive character of that process. Thus, the characters create themselves through their self-representations and thereby reveal themselves to be fictional subjects composed of various quotations. Finally, the article outlines Wieland’s programme of self-formation and self-moderation as a counter-model to modern understandings of the subject. Since the eighteenth century, the self has tended to be conceived of as autonomous, authentic, original, and final. This concept has only come to be questioned once again in the age of late modernity, by critics who draw on techniques analogous to Wieland’s.
Upaya Mengembangkan Kreativitas Mahasiswa Melalui Pembelajaran Model Project Based Learning
Authors: Astriani Maya Masitha
Published: April 2020

Abstract — The purpose of this study is to describe the creativity of students through the learning of Project Based Learning. The research was conducted with One-Shot Case Study design with 28 students of Mathematics Education study program of Indraprasta PGRI University. The research data is obtained from analysis of report and product observation sheet. Data analysis with percentage technique and processed descriptively. The research result shows that by using project based learning the students are able to develop and produce mathematics props. It is proven by assessment report with range of the score of 80 – 85 and assessment product with range 82 – 88 in the best criteria. It can be concluded that the learning with Project Based Learning model can improve student creativity. Keywords — Project Based Learning, Creativity, Props Abstrak — Tujuan penelitian ini adalah untuk mendeskripsikan kreativitas mahasiswa melalui pembelajaran Project Based Learning. Penelitian dilakukan dengan desain One-Shot Case Study dengan subjek penelitian 28 mahasiswa program studi Pendidikan Matematika Universitas Indraprasta PGRI. Data penelitian diperoleh dari analisis lembar observasi laporan dan produk. Analisis data dengan teknik persentase dan diolah secara deskriptif. Hasil penelitian menunjukkan bahwa dengan menggunakan pembelajaran proyek, mahasiswa telah mampu mengembangkan dan menghasilkan alat peraga matematika dengan baik, dibuktikan dari penilaian laporan dengan rentang skor yang diperoleh antara 80 sampai dengan 85 dan dari penilaian produk dengan rentang skor 82 sampai dengan 88 dengan kategori sangat baik. Dapat disimpulkan bahwa pembelajaran dengan model pembelajaran Project Based Learning dapat mengembangkan kreativitas mahasiswa. Kata Kunci  — Project Based Learning, Kreativitas, Alat Peraga
METHODS IN CRIMINALISTICS
Authors: Zhuravel V.
Published: April 2020

The genesis and current condition of scientific approaches to defining methods in criminalistics are considered. It is noted that, despite the significant importance for the formation of the methodology of criminalistics science, no separate doctrine of its methods has been created yet. Conversely, scientists offer different definitions and classification constructions of methods of this science. There is not always a justifiable division of criminalistics methods into research methods and methods of practical activity. It is emphasized that the introduction of a single, unified, consistent classification of methods in criminalistics science is a prerequisite for the further effective scientific research in this area of knowledge and the solution of praxeological tasks in the activity of judicial investigative bodies, expert institutions, operational units. Finding out established approaches to the classification of methods in science of criminalistics will contribute to the final formation of the modern scientific criminalistics paradigm.
In view of the results of the analysis of scientific approaches, it is proposed to divide the methods in forensics into two varieties, using the following terms: 1) methods of criminalistics that means methods of studying the subject of research of this field of knowledge, carrying out scientific research; 2) criminalistics methods, that is, the optimal methods of action of authorized subjects that are the result of the conducted research and recommended for practical use. Methods of criminalistics should be grouped into the following levels: philosophical, general scientific (methods of empirical research, methods of theoretical research, general logical methods), separate scientific (special) (borrowed, transformed, especially criminalistics). In turn, forensic methods can be divided into: methods of collecting, recording and investigating evidence; methods of using forensic and special techniques; methods of conducting individual investigative (search) actions; methods of designing and testing investigators, court, expert versions and construction of forecasting models, etc. The above points out that in the forensic scientific knowledge there is a complex, dynamic, subordinated system of numerous methods of different levels, spheres of action, directions, which are realized taking into account specific conditions and subject of research. At the same time, this system is open and constantly updated with new methods as a result of their development and renewing.
DETERMINATION OF ADMINISTRATIVE PROCEDURES FOR FORENSIC SCIENCE ACCREDITATION
Authors: Khosha V.
Published: April 2020

With the declaration of independence of Ukraine, a new stage of the state has begun, accompanied by radical changes in all areas of public life. A person, his life and health, honor and dignity, integrity and security are determined by the highest social value. Therefore, the main duty of the state proclaims the assertion and protection of human rights and freedoms, for which a whole mechanism is created and functioning, each of which elements performs separate tasks in order to achieve a common goal. Forensic institutions are part of the relevant system and contribute to the establishment of objective truth in cases of violation of law, the rights and freedoms of participants in the process through an objective and fair trial or an objective basis for evaluating the results of pre-trial investigation bodies. In addition to performing these tasks, forensic institutions in Ukraine have a number of necessary conditions for carrying out conformity assessment activities, and therefore, with some transformations of the management system, technical and other improvements to meet the requirements of national standards, harmonized with relevant international and European standards in the field of assessment compliance, state specialized agencies can be accredited for compliance with the requirements of the standard ISO/IEC 17025 (as well as ISO/IEC 17020) and carry out conformity assessment activities in a specific industry.
The article is devoted to the definition of administrative procedures for the accreditation of forensic institutions of Ukraine. Attention is focused on understanding the essence of administrative procedure and their place in the process of accreditation of conformity assessment bodies. The author analyzes the scientific approaches to considering the classification of the category “administrative procedure”.
According to the results of the study, it can be stated that the administrative procedures for the accreditation of forensic institutions of Ukraine characterizes the procedure for authorized entities (national accreditation body of Ukraine) to carry out legally significant actions, the totality of which constitutes the legal process of accreditation; procedural requirements for these entities.
ISSUES OF CHARACTERIZATION OF WHEELED VEHICLES WITH HYBRID ENGINES IN ACCORDANCE WITH THE UKRAINIAN CLASSIFIER OF GOODS OF FOREIGN ECONOMIC ACTIVITY
Authors: Mykhalskyi О. , Fokin D. , Kiriakov S.
Published: April 2020

This article discusses the problematic issues of the study of the characteristics of wheeled plug-in hybrid electric vehicles (PHEVs) in accordance with the requirements of the Ukrainian classification of goods of foreign economic activity. Existing types of hybrid power plants are considered. We consider the problems that are solved by experts in automotive industry in the study of wheeled vehicles with hybrid power plants. Problems of determining the type of hybrid power plant of a wheeled vehicle, the principle of its operation, and, consequently, the influence of this on the determination of the code according to the UKT ZED (Ukrainian Classification of Goods for Foreign Economic Activity) are considered. Currently, in expert practice, there is no single approach in carrying out research to determine which characteristics the wheeled vehicle meets according to the Ukrainian Classifier of Goods of Foreign Economic Activity. In this article the main types and types of hybrid power units, the principles of their operation and the effect on the definition of the code under the UKT ZED are given.
In relation to wheeled vehicles to one or another code under the UKT ZED it is necessary to determine the scheme of the operation of the hybrid power plant. In this case, hybrid power units operating on a parallel and serially parallel circuit should be classified in the code of code 8703 2 "Other vehicles with spark ignition internal combustion engine and crankshaft coupling" or 8703 3 "Other vehicles from an internal combustion engine with compression ignition (diesel or semi-diesel), and hybrid power plants that operate in a sequential scheme to the code number 8703 90 90 00 "other" as not falling under the requirements of the other the position of the booty on the principle of its work.
ISSUES OF CONTEMPORARY STATE OF FORENSIC PSYCHIATRIC AND PSYCHOLOGICAL EXAMINATIONS
Authors: Yegorov V. , Yegorovа T.
Published: April 2020

The problem of determining the limits of competence of a forensic psychiatrist expert and a psychologist expert, the principles of interaction of law, forensic psychiatry and psychology in modern domestic expert practice remain relevant to the present day. The current legislation of Ukraine regulates expert compliance with the limits of competence. In jurisprudence and psychiatry, the issue of the definition of the concept of “insanity” is currently debatable, since the so-called “formula of insanity” contains medical (biological) and psychological (legal) criteria.
This article purpose The purpose of this paper: presenting of the author's systemic model of ascertaining insanity, which delimits the competences of lawyers and an expert psychiatrist; A written description of the psychiatric criteria (diagnostic, criticality and anamnestic) of determining the mental state of a person in a legally relevant period of time is given; The definition of the concept of “insanity” is formulated.
No less urgent is the problem of further improvement and bringing into compliance of certain paragraphs the Procedure for conducting a forensic psychiatric examination of the current legislation of Ukraine and departmental regulatory acts governing the organization of forensic expert activity in state specialized expert institutions. Separate provisions of the Procedure for conducting a forensic psychiatric examination, which can create significant difficulties in the work of a forensic psychiatrist, are analyzed, and appropriate proposals are made to change the content of problematic provisions in the specified regulatory document.
POSSIBILITIES OF FORENSIC VETERINARY AS A NEW TYPE OF FORENSIC SCIENCE
Authors: Yatsenko I. , Derecha L.
Published: April 2020

The article is devoted to a new type of forensic examination - forensic veterinary examination. Possibilities of forensic veterinary examination are substantiated. A description is given of the subject, objects, subject, tasks of the forensic veterinary examination, a list of questions that are put to the expert to solve them. It is shown that new and existing types of criminal acts contribute to the growth of tension in the world and cause the emergence of new objects and tasks of expert research, and, therefore, new special knowledge, the latest research methods and tools are needed. The need to open a new type of forensic examination in the system of forensic institutions of the Ministry of Justice of Ukraine, forensic veterinary examination, is due to the fact that violation of quarantine conditions, purchase and sale of animals, their improper use for breeding and other purposes, poaching, cruelty to animals, as well as a violation of the rules for the disposal of corpses leads to criminal proceedings and court cases, and, consequently, the need for a forensic examination. Forensic veterinary examination covers a wide range of knowledge and research relating to live animals, their corpses, livestock, medicines used in veterinary medicine, documentation. Opening of a new expert specialty - “Forensic Veterinary Expertise” in the system of the Ministry of Justice of Ukraine contributes to the solution of many issues that arise in law enforcement in investigating offenses related to objects of veterinary medicine and animal husbandry, enriches new opportunities for domestic forensic activities, creates relevant prospects for research in this field.
SOME ISSUES OF FORENSIC RESEARCH ON ADMINISTRATIVE ADMINISTRATION BY A COMMANDER (CHIEF) AFTER IMPLEMENTATION OF JUDICIAL EXPERIENCE TASKS
Authors: Shebalkov I.
Published: April 2020

Analysis of the participation of military units of the Armed Forces, law enforcement agencies and military formations of Ukraine in the fighting showed that more effective use of the combat capabilities of units and military formations in modern conditions, the decisive value is used as a factor a control. One of the main tasks of managerial activity is decision making. In many spheres of life of any person, whether a Manager at work or the commander (chief) of military unit, the decision-making process is the basis of management activity.
The purpose of this article is a study by theoretical analysis of the procedure for adoption of administrative decisions of the commander (chief) at the court of military forensic examination.
The analysis of scientific works of modern Ukrainian and foreign scientists who were engaged in the study of the theoretical and practical aspects of the process of decision-making has shown that these works contain provisions that are different from each other. For the result of the analysis was reviewed and revealed the contents of the concepts "decision", "management decision", "management activities of the commander (chief)".
It should be noted that the main activity of an officer (chief) at any level is the management activity, which determines the form, content and direction of the entire military team, because the commander's decision is the basis of the process of managing the military team.
It was also revealed the main aspects and factors that affect the decisions of the commander (chief) of military unit with the participation in the fighting. After all, in the course of his professional activity there are tasks that are different in meaning and that are constantly changing over time. Conducted by forensic experts, the content and sequence of the commander's work in the execution of the combat mission provided opportunities for optimization of research methods, in determining the effectiveness of managerial decisions that were made by the commander using the study algorithm. The attention is focused on the existence of a deficit of scientific and methodological support of judicial expertise of the military.
MAIN APPROACHES TO DETERMINING THE EFFECTIVENESS OF FORENSIC EXPERT ACTIVITY: ADMINISTRATIVE AND LEGAL ASPECTS
Authors: Ovsiannykova I.
Published: April 2020

One of the most significant indicators in the law is the effectiveness of administrative-legal regulation. The development of the field of forensic expert activity and its stable functioning are directly related to the level of efficiency of its administrative-legal regulation.
At the present stage of development of our country, the problem of assessing the effectiveness of law is becoming increasingly relevant. Europeanization of Ukraine requires a new understanding of the problems of the interaction of the legal system and personality, the search for new approaches to the concept of the effectiveness of administrative law, including in the field of forensic expertise.
To objectively reflect the trends in the development of public life and the effective resolution of problems, administrative law in Ukraine needs to be reoriented from the state center-centered to human centered ideology, whose purpose is to ensure the rights and freedoms of man.
Activities aimed at ensuring the effectiveness of administrative and legal regulation of forensic expert activity should be based on a well-balanced scientific basis. At the same time, today, the assessment of the effectiveness of the legal acts regulated by forensic expert activity in Ukraine is not ensured by a sufficiently universal scientific teaching and practical recommendations for its realization. It should also be noted that there is no comprehensive study devoted to the effectiveness of administrative and legal regulation of forensic expert activity in Ukraine.
Аnalysis of the concept of effect, effectiveness is made in the article. Conditions and factors that may have an impact on the effectiveness of legal norms are considered. The scientific principles for determining the effectiveness of administrative and legal regulation of forensic-expert activity are investigated.
FEATURES OF FORENSIC EXPERTS RESEARCH CASES OF ARTILLERY SHOT
Authors: Bogdanyuk I. , Chuprun V. , Ustimenko V. , Shipilov M.
Published: April 2020

Attention is focused on the interdependence of the relevance of publication with a shortage of scientific and methodological support for forensic research related to the facts of the shelling. The views of international organizations on the use of explosive weapons are presented. It was determined that the use of explosive weapons in populated areas poses a danger of humanitarian problems, which include immediate and long-term consequences for the life and health of civilians, as well as affect civilian infrastructure and the functioning of life support services.
Attention is drawn to the dependence of the possibility of access for military personnel who plan to conduct hostilities (operations) in settlements to information on the location and nature of the activities of critical infrastructure facilities and basic life support services of the population on specific conditions.
Massive use of high-explosive ordnance in modern armed conflicts is noted. The development trend of this type of ammunition is highlighted. The main damaging factors of the fragmentation and high-explosive ordnance are determined and their characteristics are given. The mechanism of the formation of signs of the direction of an artillery shot to be documented at the scene of the incident is considered.
The basic methodological approaches to the study of issues put to resolution in the designated judicial military examinations related to the facts of shelling are shown. The list of basic terms and the most characteristic sources of information about the circumstances of the shelling is given. The main approaches to the procedure for recording the facts of the use of explosive weapons in settlements, as well as in the verification and analysis of relevant data and information regarding the determination of the types of weapons used in shelling, are determined. The list of basic input data required for the study is given.
Attention is drawn to the inevitability of the presence of contradictions in the results of documentation, as well as approaches to resolving them are indicated.
MODELING OF THE MECHANISM OF VEHICLE OVERTURNING IN THE PROCESS OF DEVELOPMENT OF ROAD TRAFFIC ACCIDENT
Authors: Povalyaev S. , Saraiev O.
Published: April 2020

The development of mathematical models of vehicle overturning has been given significant attention by many researchers because of the need to obtain reliable information on the circumstances of road traffic accidents. Research of road traffic accidents with the overturning of vehicles is related with the difficulty to determinate the mechanism of overturning, because expert calculation methods do not always use the adapted mathematical models. Most of the methods focus on determining the minimum (critical) speed of vehicles, which leads to its overturning. However, the real speed of vehicles before overturning can be much higher. In this paper, a mathematical model of the process of vehicle overturning after a collision with an immovable lateral obstacle is given. Thus the overturning moment caused by the inertia forces acts on the vehicle, and the moment from the gravity that holds the vehicle from overturning. It is necessary to mark that the shoulder of moment from gravity changes from a maximal value to 0 in the process of vehicle overturning. The mathematical model is based on the basic equation of dynamics for rotational motion. The developed mathematical model is a nonlinear homogeneous differential equation of second order. A solution of this equation is obtained that allows us to determine the conditions for the vehicles overturning and to investigate the basic parameters of the movement of vehicles in the process of overturning from the moment when the center of mass of the vehicle begins to rise until the moment of its maximum lifting. A comparison of the results of calculating the critical speed of vehicles with results obtained on the basis of the law of energy conservation was carried out. The results are fully agreed. The numerical results obtained using a mathematical model for a particular vehicle have been analyzed.
INVESTIGATION CASES OF ROLLING STOCK DERAILMENT USING MATHEMATICAL MODELING
Authors: Batig А. , Kuzyshyn A.
Published: April 2020

The purpose of this article is to analyze the need to apply the methods of mathematical modeling when performing examinations of rolling stock derailment.
The description of the dynamic behavior of rolling stock when moving on the track is a rather complicated, time-consuming process, which requires highly qualified expert and time-consuming.
The presence of detailed mathematical models of the constituent units of the rolling stock would greatly facilitate the study of cases of their derailment.
At present, a significant number of scientific papers are devoted to the study of the dynamics of rolling stock movement using mathematical models.
In Lviv NDISE, investigations of such railway accidents as rolling stock derailment from the rails are performed by experts according to the methods developed by the doctor of technical sciences Sokol E. M., allowing to take into account a certain number of parameters of wagon running gears.
At present, when experts examine the cases of rolling stock derailment, there is a need to develop new methods that would allow to take into account more parameters of the undercarriage parts of the wagons, such as: parameters of the damping system, spring suspension, bolster, node of the body-bogie bolster center plates, etc. P. There are also cases of railway accidents, in which one of the reasons may be the presence of defects on the rolling surface of the wheels of the rolling stock.
In this regard, experts of Lviv NDISE to take into account the above-mentioned parameters of the running gears and to identify the most significant for rolling stock derailment, it was developed object-oriented programming in the computer environment Maple.
At present, have developed a mathematical model of a passenger car of a diesel train, the DPKr-2, and an improved mathematical model of a freight wagon.
The authors of the article came to the conclusion that the use of mathematical models and their computer solution can facilitate the process of researching rolling stock cases from the rails, as it allows automating and speeding up the study of dynamic indicators of rolling stock, facilitating the process of establishing the limiting values of its technical condition parameters and assessing the consequences changes in these parameters in certain working conditions.
JUDICIAL ECONOMIC EXPERTISE AS A REGIONAL TOOL FOR MANAGING MANAGERIAL DECISIONS
Authors: Khomumenko O.
Published: April 2020

Separation of economic information of conflict situations, created by the DOJ forensic examination of the general array of economic information and study of the mechanism and the consequences of its impact on management decisions, improving the mechanisms for its creation will allow obtaining an economic effect from a positive impact on management decisions in the long run.
Destruction of criminal schemes of interactions is a logical stage in the development of the economy on the path towards the formation of a quality economy of the region. Therefore, it is logical to have the tools that provide this process. Forensic economic expertise, the author is considered as a modern form of one of the tools that participates in a complex of actions to destroy the forms of undesirable economic systems, creating a "chaos" as a prerequisite for the creation of new ones. At the same time, the formation of these prerequisites does not guarantee the fundamental quality of the new systems of economic interactions. Thus, the process of forming a high-quality economy should be aimed not only at the elimination of the consequences of administrative decisions that are undesirable for the economy of the region, not only for the formation of a "fear" to be punished for it, but also for the formation of prerequisites for the acceptance by managers at the micro level of decisions that will provide a positive direction of economic development of the region as a whole.
The activity of a separate research institute of forensic examinations of the Ministry of Justice of Ukraine has a regional status, regional closure and regional effectiveness, that is, we deal with the object, above all, the regional level of integrity and manageability. At the same time, all research institutes of forensic examinations of the Ministry of Justice of Ukraine work on the same principles and use the same methods of conducting forensic examinations included in the register of certified expert methods.
EXPERT STUDY OF CAUSAL RELATION FOR ARRANGEMENT OF WORK AT WORKING AREA
Authors: Mukha О. , Shaikhlislamova І.
Published: April 2020

Coal mining at working areas of coal mines is a complex and multifaceted process causing a wide range of hazards for employees. Arrangement of work at working area is determined by many acts of legislation and regulatory acts in labour safety. The circumstances are likely to cause safety rules violation resulting in incident (emergency, safety incident). The study of such situations requires a forensic expert to be familiar with the proper methodological base of mining and engineering expert study.
Aim of the paper: to develop a model of casual relation determining between safety incident occurrence and persons, whose action (inaction) resulted in incident preconditions during the technological process at working area.
For reliable results obtaining the following methods were applied: analysis of acts of legislation and regulatory acts in labour safety, as well as engineering and logical analysis.
Practical paper results consist in determining a group of persons, whose action (inaction) resulted in incident preconditions during the technological process at working area of coal mine, by forensic expert carrying out mining and engineering expert study by means of the model of casual relation.
Considering the results of analysis of acts of legislation and regulatory acts in labour safety determining the requirements to the technological and project documents for working area with application of engineering and logical approach the model was developed for casual relation determining between safety incident occurrence and persons, whose action (inaction) resulted in incident preconditions during the technological process at working area. The model is helpful for determining the peculiarities of action (inaction) of persons being under the proper conditions in direct or indirect casual relation with an incident.
ABOUT TECHNIQUE CREATION OF AN INTERDISCIPLINARY RESEARCH ON VEGETABLE ORIGIN TRACES
Authors: Grosheva O.
Published: April 2020

Issue of developing appropriateness a technique for establishing a mechanism for formation of vegetable origin traces on clothing items is investigated. Argument is given about the need to develop such a technique is based on special literature analysis. It is important to use specialized expertise in the form of forensic science including interdisciplinary research to make a correct and objective decision in this case. As a rule, interdisciplinary forensics is an interdisciplinary research because it integrates the knowledge of various branches of science. As separate categories, forensic biological examination and forensic trace evidence analysis have a sufficiently developed scientific base. At the same time, regarding their integration in the form of interdisciplinary researches; there is a shortage of appropriate techniques. This directly relates to the need of developing a technique for establishing green layers on object carriers (garments). It is argued that only integration of the forensic biologist (botanist) knowledge about the nature of vegetable origin layering in combination with the specialized expertise of a forensic trace evidence expert based on tracing mechanisms will lead to a scientifically based result. A series of experiments was carried out which results revealed complexes of signs enough to establish the contact nature (static, dynamic) and the movement direction during dynamic contact. This allowed us to conclude that next series of experiments would be expedient which would simulate circumstances of the contact of clothes with the vegetation of various terrain sections during the crime commission. Together, the experiments will become the basis for creating technique for the mechanism detection of green layer formation on clothing.
Creating Diagnostic Assessments
Authors: Chamberlain Darryl J , Jeter Russell
Published: April 2020

The goal of this paper is to propose a new method to generate multiple-choice items that can make creating quality assessments faster and more efficient, solving a practical issue that many instructors face. There are currently no systematic, efficient methods available to generate quality distractors (plausible but incorrect options), which are necessary for multiple-choice assessments that accurately assess students’ knowledge. We propose two methods to use technology to generate quality multiple-choice assessments: (1) manipulating the mathematical problem to emulate common student misconceptions or errors and (2) disguising options to protect the integrity of multiple-choice tests. By linking options to common student misconceptions and errors, instructors can use assessments as personalized diagnostic tools that can target and modify underlying misconceptions. Moreover, using technology to generate these quality distractors would allow for assessments to be developed efficiently, in terms of both time and resources. The method to disguise the options generated would have the added benefit of preventing students from working backwards from options to solution and thus would protect the integrity of the assessment.
Влияние толщины катодного покрытия на работу литий-ионных аккумуляторов
Authors: Капарова В , Ташенов А , Омарова Н , Абдрахманова А
Published: April 2020

Как и все типы аккумуляторов литий-ионные аккумуляторы также состоятиз анода, катода, сепаратора и электролита. Каждый из них выполняет определеннуюспецифическую функцию в устройстве. Положительный электрод непосредственно принимаетионы лития в процессе разряда аккумулятора, создавая электрохимическое напряжение.Неотъемлемыми компонентами катода являются катодный материал, проводящая добавкаи полимерсвязующее вещество. Выбор каждого из них основывается на их физических ихимических свойствах, обеспечивающих успешную работу аккумулятора. Так же для успешнойработы аккумулятора немаловажно правильная и рациональная укладка перечисленныхкомпонентов, а именно конструктивные свойства катодного покрытия: прочность, пористостьи толщина. В данной работе показана зависимость гальваностатических показателей катодаот его толщины. Толщина катодных покрытий составляла 200, 400 и 600 микрометров. Катодс толщиной покрытия 400 микрометров показал наилучшую удельную емкость на граммактивного материала.
Теория нейронной сети на основе противоположно заряженных полиэлектролитных гидрогелей
Authors: Сулейменов И , Копишев Э , Витулева Е , Молдахан И , Мун Г
Published: April 2020

Предложена схема квазибиологической нейронной сети, основанной наиспользовании пар противоположно заряженных полиэлектролитных сеток, через которыепротекает раствор низкомолекулярной соли. Каждая такая пара становится генераторомЭДС. Обратные связи в такой сети возникают за счет взаимодействия токов, протекающихвнутри пар через окружающий раствор. Предложенная схема топологически эквивалентнанейропроцессору Хопфилда. Обсуждаются вопросы использования предложенной схемы дляинтерпретации механизмов эволюции, предшествующей биологической.
Химическое исследование флавоноидов Verbascum orientalе(Коровяк восточный)
Authors: Мукажанова Ж , Кабдысалым К , Ныкмуканова M
Published: April 2020

В настоящее время среди населения Республики Казахстан широкораспространено потребление биологически активных веществ, извлекаемых из лекарственныхрастений. Поэтому весьма актуальны изучение растительной флоры Казахстана, поискновых источников биологически активных веществ и получение натуральных медицинскихпрепаратов из местных лечебных растений. Целью исследования является выделение иидентификация флавоноидов из растительного сырья Verbascum orientale (коровяк восточный)семейства Scrophulariaceae (Норичниковые).В данной работе впервые отражены результаты выделения и идентификации флавоноидов,содержащихся в экстрактах надземной части растений вида Verbascum orientale семейства Scrophulariaceae, собранных в период плодоношения в августе - сентябре 2018 г. В восточномКазахстане.Для выделения флавоноидов использованы методы последовательного извлечения иабсорбционная колоночная хроматография с силикагелем.Результаты изучения флавоноидов показали, что из надземной части растения рода Verbascum orientale выделено индивидуальное вещество – лютеолин. Структура полученногоиндивидуального вещества идентифицирована современными физико–химическими методамина основании химических превращени
Исследование ингибирующей способности неорганических циклофосфатных композиций
Authors: Ниязбекова А , Шакиров Т
Published: April 2020

В статье рассмотрены антикоррозионные свойства неорганическихциклофосфатных композиций по отношению к стали Ст-3 в зависимости от рН среды, природыи концентрации циклофосфата, природы иона модификатора. Исследования проводилисьпо гостированным методикам. Методы исследования: гравиметрия, потенциометрия,фотоколориметрия, ИКС и РЭМ. На основании экспериментальных данных определеныколичественные показатели коррозионного процесса: скорость коррозионного процесса,степень защиты, глубинный показатель, коэффициент торможения и проведена оценкаустойчивости образующейся пленки по бальной шкале коррозионной стойкости поотношению к стали. Анализ экспериментальных данных позволяет установить влияниевышеназванных факторов на протекание коррозионных процессов в исследуемых системах.Экспериментальные данные дополнены термодинамическими расчетами параметровкоррозионного процесса, результаты которых хорошо коррелируют с кинетическимиданными исследуемого процесса. В ходе исследовательской работы также проведен анализкоррозионных отложений. Установленные в ходе работы закономерности, способствуютсозданию эффективных циклофосфатных ингибиторов с наивысшими степенями защиты.
Использование природных глин в катализе
Authors: Шораева К , Масалимова Б , Садыков В
Published: April 2020

Рациональное использование природных ресурсов является одним изважных проблем современного Казахстана. В этом плане природные глины представляютособый интерес для синтеза новых катализаторов, сорбентов и носителей. В данной статьепредставлен обзор сведений об использовании природных глин в области каталитическойхимии в качестве катализаторов, адсорбентов и носителей. По результатам исследованиявыяснилось, что, использование природных модифицированных глин в катализе поможетрешить вопросы развития отечественного производства синтеза катализаторов, адсорбентови носителей, замены их дорогих импортных аналогов.
Verbascum orientale L. өсiмдiгiнiң химиялық құрамын гибридтi хроматография әдiсiмен талдау
Authors: Мукажанова Ж , Қабдысалым К , Ныкмуканова M , Ескалиева Б , Бейатли А
Published: April 2020

Қазiргi таңда дүние жүзiнде дәрiлiк өсiмдiк өнiмдерiне назар аударылуда.Қазақстан Республикасы табиғи препараттарды өндiруге қажет шикiзат қорына бай мемлекет.Eлiмiздiң шығыс өңiрiндегi әртүрлi зоналық аймақтар өсiмдiк флорасының алуантүрлiлiгiнайқындай түседi. Өсiмдiктердiң морфологиялық формасы мен анатомиялық құрылымыолардың өсу жағдайы мен ортасына байланысты. Бұл факторлар өсiмдiк құрамындағыминералды заттар мен биологиялық белсендi заттардың (ББЗ) мөлшерi әртүрлi болуына әсеретедi [1].Заманауи талдау әдiстерiмен өсiмдiк шикiзаттарының компоненттiк құрамын толық зерттеужаңа табиғи дәрiлiк препараттарды ашуға үлкен мүмкiндiк бередi.Жұмыста алғаш рет Қазақстанның Шығыс өңiрiнен жемiс беру кезеңiнде жиналған Scrophulariaceae (Сабынкөкгүлдiлер) тұқымдасына жататын Verbascum orientale L. (шығыс аюқұлақ)өсiмдiк түрiнiң гександы сығындысын GC–MS (газды хроматография - масс - спектрометрия)әдiсiмен зерттеу нәтижелерi берiлген.Verbascum orientale L. өсiмдiгiнiң шикiзатынан 6 жеке зат идентификацияланды, олар:миристин, пальмитин, стеарин, пальмитолеин, олеин, линол қышқылдары. Көрсетiлгеннәтижелер бойынша: Verbascum orientale L. өсiмдiгiнiң сандық құрамында жоғары көрсеткiшкөрсеткен: қаныққан май қышқылы: пальмитин (16,32%) және қанықпаған май қышқылдары:линол (43,61%), олеин (12,87%).
Tool Wear Suppression Methods of Diamond-cutting Ferrous Metals
Authors: GUO JIANG
Published: April 2020

This entry introduces some common tool wear suppression methods of diamond-cutting ferrous metals.
（Created By Guo Jiang and Liu Guangyu)
Applications of Cyclodextrins Modified/Coated Metal–Organic Frameworks
Authors: Zhang Huacheng
Published: April 2020

The introduction of cyclodextrins (CDs) via noncovalent bonds could improve various physiochemical properties of metal-organic frameworks (MOFs) and expand their practical applications in aqueous solutions, for example, biocompatible CDs could improve the solubility of CDs-coated MOFs as a hybrid delivery system. And external-stimuli responsiveness of CDs-coated MOFs is key for widening applications in controlled drug releasing system, catalysis, detection, extraction and separation.