bluuebunny/crossref_metadata_2025 huggingface dataset:
Too Much of a Good Thing: High T Cell Count Can Kill Newborns
Authors: Bustos Angelina , Xu Lai , Dunsmore Garett , Elahi Shokrollah
Published: October 2019

Neonates have a weakened immune system that could be due to low exposure to pathogens resulting in low adaptive immunity and/or purposeful immune suppression to protect the weak neonate from a robust immune response. The purpose of this project is to find preliminary data to further investigate why the immune system of neonates are weaker, and to possibly improve neonatal immunity while protecting against a powerful immune response in the future.  Using processed mice spleen cells that were stained for CD4 and CD8 to be subjected to flow cytometry, an increase in the percent of helper CD4 and killer CD8 T cells were observed as the mice aged. This indicates that neonates do have a weaker immune system. Between healthy mice and mice infected with either Bordetella pertussis or Listeria, a decrease in the percent of CD4 and CD8 T cells were found, which could be because not enough time had passed for an adaptive immune response.
Sickle cell disease in African immigrant children: A scoping review
Authors: Zahoni Ziad , Salami Bukola , Kariwo Micheal , Fernandez-Sánchez Higinio
Published: October 2019

Despite the research on African-America parents, children and families who suffer from sickle cell disease (SCD), less is known about African immigrant children who migrated outside of Africa. Therefore, the purpose of this scoping review was to assess the extent, range, and nature of the existing index of research on African immigrant children with SCD living outside of Africa, to map out research activity and to identify gaps in the existing literature. This review followed the scoping review methodology of Arksey & O’Malley. A comprehensive search in ten electronic databases was conducted. The search strategy combined the keywords “sickle cell” and “African immigrant children”. Inclusion criteria focused on research published between 2000 and 2019, reporting on the health of African immigrant children aged 0 to 18 years. Systematic & literature review reviews, conferences, case studies, viewpoint articles, & epidemiology studies were excluded. Also, studies in which findings were based on mixed populations containing less than 80% African immigrant children, were excluded from the review.

This review was guided by the five-step approach to scoping reviews of Arksey & O’Malley. Articles were included if they focused on African immigrant children living abroad. Two independent reviewers screened and selected articles. We analyzed and synthesized data using thematic analysis for qualitative data. The search yielded 6,602 records. After removing duplicates and titles, and abstracts were screened, 1,675 articles were included for full-text screening; 6 met inclusion criteria. Chain searching generated 10 articles, 1 met the inclusion criteria. Seven articles were included for analysis. The studies were all quantitative in design and none mentioned a theoretical framework. Even though all the studies were quantitative the usage of clinical assessment of the only means of attaining data, and the usage of insufficient sample size made the studies found, inconclusive in making generalizations. There are significant research gaps regarding African immigrant children with SCD living outside of Africa. A major limitation of the studies use is they were all conducted in Italy even though there are many other countries known to host immigrants from the African continent.  Furthermore, most of the studies only state the disadvantages this population faces and only two studies took the initiative in addressing these issues. Overall, this review underlines the need for future research on the impact of migration on the health outcomes of African immigrant children with SCD living outside of Africa.
Status Nutrisi Kerbau Betina di Peternakan Rakyat Cibungbulang: Pengaruh Suplementasi Indigofera sp dan Gaplek terhadap Perubahan Profil Darah
Authors: Sudarman Asep , Hidayati N , Suharti S
Published: October 2019

This study aimed to evaluate the effect of Indigofera sp and cassava flake supplementation on the nutritional status of female buffaloes fed on rice straw and field grasses in smallholder farmers in Cibungbulang, Bogor. This study used four female buffaloes of 4-10 years old and an average body weight of 428.88 ± 86.05 kg. The treatments were T0 = without supplementation and T1 = supplementation of 50% Indigofera leaf and 50% cassava flake. The variables observed were body weight gain, blood glucose, cholesterol, total protein, albumin, hematocrit and hemoglobin. Data were analyzed using Paired Samples T-test. The results showed that the nutritional status of buffaloes that were reared in semi-intensive were in normal condition. Supplementation of Indigofera sp and cassava has a positive influence on body weight gain, blood metabolite levels, hematocrit and hemoglobin of female buffaloes. Daily weight gain was obtained at 732.1 g head-1day-1.   Blood glucose increased from 53.97 to 60.86 mg dL-1, albumin from 3.44 to 3.78 g dL-1, blood cholesterol from 37.43 to 50.84 mg dL-1 and hematocrit from 26.75 to 29.75%.  The conclusion is that giving supplements of Indigofera and cassava for two weeks can improve the nutritional status of buffaloes reared traditionally.
The Thinking Path of Deepening Transformation and Innovation of Chinese Banking Industry under the Background of “New Normal” Economy
Authors: Zhang Guaili
Published: October 2019

This paper analyzes the three big impact in the development of Chinese banking industry and discusses the limitations of financial innovation of Chinese banking industry. The results showed that: (1) deepening the banking system innovation to adapt to the new situation; (2) improving customers’ experience by deepening model innovation of the internet financial; (3) improving intensive of bank branch operation and the intelligent of network service with the aid of informatization; (4) Providing individualized, characteristic and differentiated services for high-quality customers of banks and enhancing customer value through lightweight network outlets; and (5) Adapting to the development of new entity economy by comprehensive management, optimizing the operation mode of outlets, and strengthening the supply side reform of commercial banks themselves.
(Re) Imagining the Intra-connections in Geography Education through the Notion of Place
Authors: Ontong Krystle
Published: October 2019

One of the challenges facing geography educators at higher education institutions in South Africa is to prepare students by providing them with an integrated conceptual and pedagogical toolkit that would adequately equip them to teach a type of geography that is current and relevant to local (but also global) environmental and social phenomena. As an intra-disciplinary science, Geography offers multiple avenues for fostering this type of integration, yet as argued elsewhere, [1] because of a fragmented school Geography curriculum, teacher educators struggle to foster holistic and integrated learning among novice student teachers. In fact, academic geographers most often privilege their own field of specialisation rather than work towards integration [2]. Ultimately, this perpetuates a fragmented teaching practice and conceptual understanding of geographical phenomena. This paper provides a theoretical exploration to demonstrate how Geography Education could retain its holistic nature and advance integration by (re)turning to its own intra-disciplinarity. It was found that the notion of “place” (one of Geography’s big ideas) could serve as a potential point of departure for fostering integrated thinking in the discipline. The argument is made that place-based approaches offer fertile avenues to pursue in Geography Education programmes for equipping student teachers with a holistic conceptual and pedagogical toolkit.
Behavioral Operations Management: A Review of the Field
Authors: Hendijani Rosa
Published: October 2019

Behavioral operations management (BOM) is one of the new areas in operations management. In the past 12 years, the field has made huge progress and researchers have become interested in this new perspective to solving operational problems. BOM is now one of the major subfields of operations management. In this paper, we examine and categorize areas of BOM based on the mainstream literature. Key areas include behavioral issues in new product development and project management, quality management, production management, inventory management, service operations, and forecasting. Studies in each area are divided into three subcategories, including OM context, individual attributes, heuristics, and biases, and individual differences. In OM context category, feedback and reward, training, work monitoring, teamwork and group decision making, goal setting, task assignment, and flexibility are among the main topics. In individual attributes, heuristics, and biases category, sunk cost effect and escalation of commitment, endowment effect, overprecision bias, planning fallacy, pull-to-center effect, anchoring and insufficient adjustment, and misperceptions of feedback are mainly discussed. In individual differences, analytic thinking and system thinking are mainly studied. New areas for research are suggested in each related section and are summarized in future directions and conclusion sections. In contexts such as new product development, project management, and inventory management, a shift to finding solution to performance improvement is beneficial instead of focusing on heuristics and biases and considering them as a deficiency in human decision making. Regarding individual differences category, a shift toward attributes other than cognitive abilities, such as global processing, creative thinking, and design thinking are recommended.
Do Stress and Anxiety Impact Memory? An Exploratory Portuguese Study
Authors: Alho Laura , Rodrigues Pedro F. S. , Fidalgo Cátia
Published: October 2019

Eyewitness memory is widely studied in the forensic context, due to their proneness to make unreliable testimonies. Understanding which factors may impact memory is determinant to avoid wrongful convictions in court. In this exploratory study, the relation between stress and anxiety and memory errors (spontaneous and induced) was analyzed being hypothesized that negative emotions may impair memory performance. Crime and neutral videos were presented to 80 volunteer university students in a between subject-design. They were asked to fill some stress and anxiety scales throughout the experimental task, as well as a free recall task. Also, it was presented several questions about the videos in which spontaneous and induced errors were assessed. Results suggests that stress and anxiety did not influence the quantity of memory errors for both genders. However, overall memory performance was poor for both groups. Our results were discussed in light to existing theories about the relation between stress-anxiety and memory.
Callus Cultures of Beans Infected With Virus as a Model for Testing Antiviral Compaunds
Authors: Oleksiy Kovalenko , Angelina Kyrychenko , Olena Kovalenko
Published: October 2019

In the work, bean callus raised from a leaves of Bean common mosaic virus infected bean plant was obtained and adapted for the testing of antiviral activity of liposomal glycan-glycolipid complexes. Ganoderma adspersum glucans and Pseudomonas spec. rhamnolipids were constituents of liposomal compaunds. It has been shown that under the long-term cultivation (up to 3 months) in the presence of a liposomal preparation containing (10-100 mg/l), the virus is eliminated from the tissue. This is evidenced by the absence of 391 bp sequence amplification product established by RT-PCR in the callus tissue, cultured on a medium containing the liposomal complex. The proposed model system is analogous to plant tumors and has obvious advantages over similar systems in vivo, since the callus growth is controlled and independent of environmental factors.
MODEL SEM-PLS TERBAIK UNTUK EVALUASI PEMBELAJARAN MATEMATIKA DISKRIT DENGAN LMS
Authors: Mardiana Novi , Faqih Ahmad
Published: October 2019

Research on the use of Structural Equation Modelling-Partial Least Square (PLS-SEM) related to Learning Management System LMS has developed very rapidly. However, in these studies, it was not explained how to choose the best model used to evaluate the relationship among latent variables in the model. This study aims to select the best SEM-PLS model related to evaluating the use of LMS in Discrete Mathematics learning based on the criteria of Q2, AIC, AICu, AICc, BIC, HQ, and HQc. Data obtained from a survey of 109 3rd semester students who took Discrete Mathematics courses at STMIK IKMI Cirebon using 5 latent variables. The Main Model is formed based on all research latent variables and evaluated by stages 1) PLS-Algorithm, 2) Bootstrapping and 3) Blindfolding. Based on the Main Model, 16 alternative models are created with the same manifest variables as the Main Model. The best model is determined based on the highest Q2 value, and the least AIC, AICu, AICc, BIC, HQ and HQc values. The results of the study show that the Main Model is better based on the Q2 value compared to other models in this study. Different results are obtained if the AIC, AICu, AICc, BIC, HQ and HQc criteria are used, where Model C2 and B2 are the best models based on these criteria
Persentuhan Filantropi Islam dan Budaya Lokal
Authors: Muhibbuddin Muhibbuddin
Published: October 2019

Pogogutat culture in the Mongondow tribe in North Sulawesi is one of the local wisdoms in Indonesia which is loaded with various meanings. This cultural presence is in contact with community activities whose purpose is to improve the quality of life of the people. Practically, the tradition of pogogutat is carried out simultaneously by the community if there is one person holding a celebration in the form of providing assistance in the form of material, energy and thoughts. Pogogutat culture among the Mongondow people can be understood among others as a form of an identity as a Muslim community that has the character of ta'awun (please help), helping each other in order to spread the symbols of Islam as part of religious advice. This tradition has a close relationship with the concept of Islamic philanthropy in this case can be interpreted as a movement, both carried out by individuals and groups with the aim of improving the quality of life of society through a "culture of giving".
Aktivitas Antiparkinson Ekstrak Gambir (Uncaria Gambir Roxb.) Pada Tikus Putih (Rattus Norvegicus) Galur Sprague Dawley yang Diinduksi Haloperidol
Authors: Nofitasari Lutfi , Peranginangin Jason Merari , Handayani Sri Rejeki
Published: October 2019

Parkinson merupakan penyakit yang terjadi akibat adanya kerusakan sel saraf dopaminergik pada bagian otak yang mengakibatkan terjadinya penurunan produksi dopamin. Gambir adalah ekstrak kering yang dibuat dari daun tumbuhan Uncaria gambir Roxb. Gambir mengandung flavonoid berupa katekin tidak kurang dari 90%, alkaloid dan terpenoid. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak gambir yang dapat mengurangi gejala parkinson pada tikus putih jantan galur Sprague dawley yang diinduksi haloperidol.Hewan uji sebanyak 35 ekor tikus dibagi menjadi 7 kelompok. Kelompok I (kontrol sehat) diberi aquadest secara per oral, kelompok II (kontrol negatif) diberi larutan CMC-Na 0,5 % p.o, kelompok III (kontrol positif I) diberi levodopa 27 mg/kgbb p.o, kelompok IV (kontrol positif II) diberi vitamin E 180 IU/kgbb p.o. Kelompok V, VI, dan VII diberi ekstrak gambir dosis berturut-turut 70; 140; 280 mg/kgbb. Seluruh kelompok diinduksi haloperidol 2 mg/kgbb i.p pada menit ke-45 setelah perlakuan kecuali pada kelompok sehat. Kemudian kelompok diuji dengan catalepsy bar test, dicatat waktu latensi yang dinyatakan dalam skor dan rota rod test, dicatat waktu latensi dalam detik pada hari ke 0, 4, 7, 11, dan 14.Hasil penelitian menggunakan metode catalepsy bar test menunjukkan % penurunan katalepsi pada ekstrak gambir dosis 70; 140; 280 mg/kgbb mempunyai aktivitas yang berturut-turut sebesar 22,53; 52,50; 57,12 %. Sedangkan hasil dengan metode rota rod test menunjukkan % kenaikan waktu latensi ekstrak gambir berturut-turut sebesar 27,69; 35,75; 39,61 %.
Village Institution in Utilizing Village Funds in Namlea District
Authors: UNIQBU PSPM
Published: October 2019

The Village fund is a government effort to support the development of the village through financing schemes that are regulated and implemented directly by the village government, the involvement of village institutions in the management of village funds into an institutional relationship that is able to Village Fund Management. This research is a qualitative study aimed to describe the relationship of village government with village institutions in the planning and implementation of development based on the allocation of village funds obtained. The research site is focused on Namlea subdistrict with the consideration of density and heterogeneity of society. The number of informant that will be interviewed as many as 40 people taken in purposive. The analytical techniques used follow the concept given Miles and Huberman. The results showed that the relationship that awakened has a positive impact on the planning, implementation and supervision of the use of the village funds with the presence of the engagement, the sense of having and responsibility to the management Village funds are not merely the responsibility of the villagers but rather to be a responsibility with the parties involved.
ANALISIS PENGARUH PROMOSI, KUALITAS PRODUK DAN BRAND IMAGE MATIC HONDA TERHADAP KEPUTUSAN PEMBELIAN SERTA DAMPAKNYA TERHADAP LOYALITAS PELANGGAN (Studi Kasus Pengguna Sepeda Motor Matic Honda Beat KOTA BOGOR)
Authors: Setiawansah Ahmad Wawan
Published: October 2019

Tujuan penelitian ini untuk menganalisis Pengaruh Promosi, Kualitas Produk dan Brand Image terhadap Keputusan Pembelian serta dampaknya terhadap Loyalitas Pelanggan (Studi Kasus Pengguna Sepeda Motor Matic Honda Beat (KOTA BOGOR)). Promosi, Kualitas Produk dan Brand Image dapat menjadi faktor pendukung bagi konsumen untuk meningkatkan Keputusan Pembelian konsumen serta dampaknya terhadap Loyalitas. Tujuan Penelitian ini adalah (1).Pengaruh Promosi Terhadap Keputusan Pembelian (2) Pengaruh Promosi Terhadap Loyalitas (3) Pengaruh Kualitas produkTerhadap Keputusan Pembelian (4).Pengaruh Kualitas ProdukTerhadap Loyalitas (5).Pengaruh Brand ImageTerhadap Keputusan Pembelian (6).Pengaruh Brand ImageTerhadap Loyalitas (7).Pengaruh Keputusan Pembelian terhadap Loyalitas jumlah responden adalah 100 responden yang diambil dari masyrakat dikota bogor yang menggunakan Honda Beat Pop. Diolah dengan SPSS versi 22, hasil penelitian adalah (1) Promosi memiliki pengaruh yang positif dan signifikan secara partial terhadap keputusan Pembelian sebesar 3,631. (2) Kualitas produk memiliki pengaruh yang positif dan signifikan secara partial terhadap keputusan Pembelian sebesar 2,182. (3) Brand Image memiliki pengaruh yang positif dan signifikan secara partial terhadap keputusan Pembelian sebesar 3,950. (4) Promosi memiliki pengaruh positif dan signifikan terhadap Loyalitas secara Parsial sebesar 2,635. (5) Kualitas Produk mempunyai hubungan yang positif dan signifikan yang signifikan secara partial terhadap Loyalitas sebesar 1.779. (6) Brand Image memiliki pengaruh positif dan tidak signifikan terhadap Loyalitas sebesar 0,948 (7)Keputusan Pembelian berpengaruh positif namun tidak signifikan terhadap Loyalitas secara partial sebesar 1,826 . (8) Uji Path Analisis Jalur 1 Y=0,337X1+0,199X2+e dan jalur 2 Z=0,324X1+0,207X2+0,132X3+0,232Y+e uji auto korelasinya 1,579 dengan nilai R-Square sebesar 71,4% sedangkan sisanya dijelaskan oleh variabel lain.
Introducing the Causal Graph Approach to Psychopathology: An Illustration in Patients with Obsessive-Compulsive Disorder
Authors: Kossakowski Jolanda Jacqueline , Oudheusden Lucas J B , McNally Richard J. , Riemann Bradley , Waldorp Lourens , van der Maas Han
Published: October 2019

Clinicians aim to discern causal relations among features of mental disorders. Yet observational data are insufficient to confirm these relations. In the present study, we describe a causal graph approach to illustrate how one can discern causal relations among features of obsessive-compulsive disorder (OCD) by applying the Invariant Causal Prediction (ICP) algorithm and the Hidden Invariant Causal Prediction (HICP) algorithm, supplemented by findings from a literature review. Applying these methods to symptom severity data from four time points (before, during [twice], and after behavioral treatment) we estimated a causal graph for OCD. The resulting causal graph reveals multiple cycles between aspects of OCD that may play a role in the maintenance of the disorder. We conclude that the proposed design has great potential and could benefit clinicians with some adjustments and extensions.
Pemberdayaan masyarakat dengan pelatihan pembuatan minuman kesehatan dari Tanaman Obat Keluarga (TOGA)
Authors: Harfiani Erna , Anisah Anisah , Irmarahayu Agneta
Published: October 2019

Kesehatan penting untuk dijaga dan pencegahan penyakit dengan menjaga kesehatan lebih baik daripada mengobati penyakit. Masyarakat Depok, Jawa Barat termasuk daerah yang subur namun cukup padat penduduknya sehingga lahan untuk menanam tanaman, termasuk TOGA terbatas. Untuk memotivasi masyarakat menanam TOGA, diperlukan pelatihan membuat minuman kesehatan yang dapat dilakukan secara mandiri untuk menjaga kesehatan sehari hari secara sederhana. Pelatihan pembuatan minuman kesehatan dapat lebih memotivasi masyarakat untuk menanam TOGA di pekarangan sekitar rumah. Pelatihan ini sebelumnya didahului dengan penyuluhan tentang TOGA dan manfaatnya terutama kunyit (Curcuma domestica) dan jahe merah (Zingiber officinale L). Pelatihan ini bertujuan agar masyarakat dapat lebih paham tentang pentingnya menanam TOGA, pemanfaatannya dalam menjaga kesehatan sehari hari dan dapat membuat minuman kesehatan. Dengan pelatihan ini juga diharapkan masyarakat dapat lebih mencegah penyakit daripada mengobati penyakit, dengan mengkonsumsi minuman kesehatan yang dibuat secara mandiri. Hasil yang dicapai dari kegiatan ini adalah meningkatnya pengetahuan masyarakat di RW 03 Depok Jaya Pancoran Mas Depok tentang pentingnya menanam TOGA di pekarangan rumah, dan mampu membuat minuman kesehatan berupa kunyit asam dan serbuk jahe merah.
Linkages between Time to Reach Education Centers, Health Facility Centers, Poverty Status and Geography: A Multivariate Approach
Authors: Uprety Pravat
Published: October 2019

Background: The first, third and fourth goals of SDG are concerned with ending poverty in all its forms everywhere, ensure healthy lives and promote well-being for all at all ages and ensure inclusive and equitable quality education and promote lifelong learning opportunities for all, respectively. Nepal is committed to ensuring all children with access to free, compulsory, and good-quality basic and secondary education in Nepal.

Objectives: This study aims to compare the average time to reach education centers and health facility centers by poverty status and ecological region.

Materials and Methods: This study is based on NLSS 2011 data. In this study two major factors of access to facility namely education and health are considered. Four variables on access to education and three variables on access to health are used. Mean vectors, correlation matrices, and covariance matrices have been computed. The Multivariate Analysis of Variance is used to compare the mean vectors and to check the homogeneity of the variance-covariance matrix using Box's M test. Four tests namely Wilk's Lambda, Lawley- Hoteling trace, Pillai trace and Roy's largest root have been used to compare the mean vectors.

Results: This study has shown that the average time to reach each nearest education center of poor households is higher than non-poor households in each ecological region. The average time to reach the primary school is lowest and highest to reach secondary school in each poverty status and ecological region. The average time to reach the nearest health post is lowest among different health facility centers in each poverty status and ecological region. The p-values of each Box's M and Pillai trace tests are less than 0.0001.

Conclusion: The mean vectors of time to reach the nearest education center are significantly different between poor and non-poor households in each ecological region. The average time to reach the health facility centers is also significantly different in poor and non-poor households within each ecological region.
Optimasi Prediksi Keputusan Calon Nasabah Potensial menggunakan Algoritma C 4.5 berbasis Particle Swarm Optimization
Authors: Dwiasnati Saruni , Devianto Yudo
Published: October 2019

Dalam era globalisasi, persaingan bisnis menjadi sangat tajam dan berwarna, baik dipasar nasional maupun di pasar internasional. Meningkatnya permintaan pasar mengakibatkan daya saing dan jumlah pesaing pelaku bisnis juga meningkat, setiap perusahaan di tuntut untuk selalu memperhatikan kebutuhan dan keinginan konsumen serta berusaha memenuhi apa yang mereka harapkan dengan cara yang lebih memiliki nilai jual atau variatif dari pada yang dilakukan oleh para pesaing lainnya. Calon Nasabah Asuransi memiliki definisi satu atau beberapa yang mengambil manfaat dari produk fisik dengan berbagai variabel yang digunakan dalam penentuan seperti harga, kualitas, jumlah produk, tempat dan layanan yang dapat disediakan berdasarkan hasil untuk mencapai hasil yang ditargetkan. Berdasarkan hal tersebut, data mining di nilai dapat membantu permasalahan dalam penentuan Calon Nasabah Potensial  untuk melakukan prediksi menggunakan tekhnik klasifikasi. Salah satu tekhnik klasifikasi yang digunakan pada penulisan ini yaitu decision tree khususnya C4.5. Pada penelitian sebelumnya yang dilakukan oleh penulis bahwa C4.5 memiliki hasil accuracy yang kurang maksimal karena algoritma C4.5 merupakan algoritma yang lemah, maka di perlukanlah peningkatan akurasi. Particle Swarm Optimization (PSO) merupakan algoritma optimasi yang dapat digunakan untuk meningkatkan algoritma lainnya agar lebih optimal hasil yang diketahui. Penulisan ini menggunakan tools Rapidminner versi 8 sebagai media untuk menguji data yang akan diolah untuk mendapatkan hasil accuracy.
Integrasi SMOTE Dan Ensemble AdaBoost Untuk Mengatasi Imbalance Class Pada Data Bank Direct Marketing
Authors: Rais Amin Nur
Published: October 2019

Kampanye pemasaran produk bank secara langsung dapat dibantu dengan adanya teknologi informasi. Dengan terus bertambahnya data dan penggunaan teklogi informasi, data yang didapatkan dapat dimanfaatkan lebih maksimal untuk membuat keputusan. Dengan teknik klasifikasi dari, didapatkan hasil penambangan data berupa akurasi dari pembelajaran yang dilakukan. Metode dalam penelitian ini dengan menggunakan preprocessing SMOTE dan ensemble AdaBoost yang dikombinasikan dengan algoritma Naïve Bayes, SVM, dan J48. Hasil eksperimen yang diperoleh menunjukkan klasifikasi dengan menggunakan Naïve Bayes untuk akurasi sebesar 88,30%, sedangkan SVM 89,68%, dan J48 memiliki akurasi sebesar 95,73%. Maka dapat disimpulkan bahwa dengan menggunakan teknik klasifikasi Decision Tree J48 yang dikombinasikan dengan preprocessing SMOTE dan ensemble AdaBoost dapat memprediksi untuk menentukan objek pemasaran secara langsung kepada konsumen.
HOW IS SOCIAL CAPITAL CONVERTED TO BE ECONOMIC CAPITAL? A CASE STUDY FROM PESANTREN’S SOCIO-ECONOMIC PROJECTS
Authors: Isbah M Falikul
Published: October 2019

There is an increasing trend among Indonesian Islamic boarding schools or locally called pesantren to address the socio-economic problems of their neighbouring communities. Over the last two decades, many pesantren have articulated that concern through operating Islamic microfinance business or popularly called BMT (Baitul Maal wat Tamwil) and other enterprise forms. However, the majority of those initiatives are not financially developing. Pesantren Sidogiri is among a few of those exhibit business success and relatively significant social benefits to the Pesantren as well as its graduates. Based on fieldwork findings and the employment of social capital theory, this paper argues that the success of Pesantren Sidogiri’s three business hubs (Kopontren Sidogiri, BMT MMU, BMT UGT) is because the Pesantren has successfully mobilised and managed its rich social capital which is embedded in the Pesantren’s social networks. That social networks have constantly been managed and developed through appropriable social organisations and closure of social networks. The former is evident in the Pesantren’s program of Affiliating Madrasah (madrasah ranting) and Teacher-Internship (guru tugas), while the latter in the Alumni Association (himpunan alumni) and the publication of monthly-Bulletin Sidogiri. These two streams have intentionally or unintentionally provided the Pesantren with a ready-use of social capital to be converted as economic capital in its economic projects.There is an increasing trend among Indonesian Islamic boarding schools or locally called pesantren to address the socio-economic problems of their neighbouring communities. Over the last two decades, many pesantren have articulated that concern through operating Islamic microfinance business or popularly called BMT (Baitul Maal wat Tamwil) and other enterprise forms. However, the majority of those initiatives are not financially developing. Pesantren Sidogiri is among a few of those exhibit business success and relatively significant social benefits to the Pesantren as well as its graduates. Based on fieldwork findings and the employment of social capital theory, this paper argues that the success of Pesantren Sidogiri’s three business hubs (Kopontren Sidogiri, BMT MMU, BMT UGT) is because the Pesantren has successfully mobilised and managed its rich social capital which is embedded in the Pesantren’s social networks. That social networks have constantly been managed and developed through appropriable social organisations and closure of social networks. The former is evident in the Pesantren’s program of Affiliating Madrasah (madrasah ranting) and Teacher-Internship (guru tugas), while the latter in the Alumni Association (himpunan alumni) and the publication of monthly-Bulletin Sidogiri. These two streams have intentionally or unintentionally provided the Pesantren with a ready-use of social capital to be converted as economic capital in its economic projects.
The Effect of Using The Manual of Collaborative Teaching Approach to Mastering the Basic Standard of Writing Malay Language
Authors: Adam Mohd Asnorhisham , Mohd Yusof Sanitah , Rahim Hamdan Abdul
Published: October 2019

The study was conducted to examine the effectiveness of the Collaborative Teaching Approach Manual (CTAM) on the mastery of the basic standard of literacy writing Malay language level one. The study was conducted by quasi-experiment using CTAM in teaching and facilitating. This study was conducted in Primary School in Pasir Gudang district which involved a sample of 70 students in year two. The two teachers involved were Remedial Teacher and Malay Teacher in this study. The t-test is used to test the hypothesis of the study. The findings showed that there was a significant difference to the experimental group using CTAM in achieving the overall basic standard of literacy writing Malay language students. The findings show that the use of CTAM is able to increase the level of literacy mastery more effectively to the pupils.
"Boys in Power"
Authors: Ólafsdottir Katrín , Kjaran Jón Ingvar
Published: October 2019

Sexual consent determines if sex is consensual, but the concept is under-researched globally. In this article, we focus on heterosexual young men and how they negotiate sex and consent. We draw on peer group interviews to understand how young men are constituted by the dominant discourses at play in shaping their realities. We have identified two different discourses that inform consent, the discourse of consent (based on legal, educational, and grassroots discourses), and the discourse of heterosexuality (based on the heterosexual script, porn, and gender roles) resulting in conflicting messages for boys. They are supposed to take responsibility for sex to be consensual as well as being gentle partners, but at the same time, the heterosexual discourse itself produces power imbalances in sex and dating.
Book Reviews
Authors: Morales Erica , Blower Alex , White Samantha , Puzio Angelica , Zbaracki Matthew
Published: October 2019

Ingram, Nicola. 2018. Working-Class Boys and Educational Success: Teenage Identities, Masculinities, and Urban Schooling. London: Palgrave Macmillan.

Pinkett, Matt, and Mark Roberts. 2019. Boys Don’t Try? Rethinking Masculinity in Schools. London: Routledge.

Agyepong, Tera Eva. 2018. The Criminalization of Black Children: Race, Gender, and Delinquency in Chicago’s Juvenile Justice System, 1899–1945. Chapel Hill: University of North Carolina Press.

Farrell, Warren, and John Gray. 2018. The Boy Crisis. Dallas, TX: BenBella Books.

Potter, Troy. 2018. Books for Boys: Manipulating Genre in Contemporary Australian Young Adult Fiction.Wissenschaftlicher Verlag Trier.
Three Concepts of Tyranny in Western Medieval Political Thought
Authors: Nederman Cary J.
Published: October 2019

During the Latin Middle Ages, as today, “tyranny” connotes the exercise of power arbitrarily, oppressively, and violently. Medieval thinkers generally followed in the footprints of early Christian theologians (e.g., Gregory the Great and Isidore of Seville) and ancient philosophers (especially Aristotle) regarding the tyrant as the very embodiment of evil rulership and thus as the polar opposite of the king, who governed for the good of his people according to virtue and religion. However, examination of the writings of some well-known and influential authors from ca. 1150 to ca. 1400—including John of Salisbury, Ptolemy of Lucca, William of Ockham, Bartolous of Sassoferrato, and Nicole Oresme—reveals three very diverse and distinct conceptions of tyranny, each of which justified the tyrant in one way or another.
Process Optimization on Rear Bumper Assembly in a PIM Two Wheels Poly Company
Authors: Barros Félix Jean , Barbosa de Alencar David , Tregue Costa Alexandra Priscilla , Estanislau Sanches Antônio
Published: October 2019

The article discusses the relevance of a proper implementation for the rear shock absorber assembly line of motorcycles in a company of Manaus Industrial Pole - PIM, considering the quality techniques and tools used in optimizations. The overall goal is to improve component distribution and rear shock mounting costs for efficiency and effectiveness in the process flow. Specific objectives are to: Avoid wasting time in the process, improve production with optimization techniques, and develop team capacity. In the problem, he observed jobs 6 and 7 with poor “distribution” of components, generating excessive spending. The question arises: How can component “redistribution” optimize and reduce costs for the business? The methodology used was exploratory research, with systematized studies through academic websites, books, bibliographic research and field research with the company with collected data. The optimization procedures were performed with the following tools: Brainstorming, Ishikawa Diagram, 5W2H and Kaizen. Therefore, this paper aims to develop knowledge about the improvements implemented in the assembly line, encouraging the application of quality tools, making it a very efficient option for the organization.
Beneficial effects of corn syrup containing maltobionic acid on bone density in healthy Japanese adult women: A randomized double-blind placebo-controlled study
Authors: Suehiro Daiki , Fukami Ken , Takara Tsuyoshi
Published: October 2019

Background: Osteoporosis is characterized by reduced bone mineral density (BMD) and increased fracture risk, with a higher incidence in post-menopausal women. This study aimed to evaluate the safety and efficacy of long-term ingestion of corn syrup solids containing maltobionic acid on BMD in healthy Japanese women.Methods: A randomized, double-blind, placebo-controlled, parallel-group study was conducted from February to December 2018. Thirty-eight healthy Japanese women aged 50–69 years who were at least 1 year past the onset of natural menopause were allocated to two groups (19 in each group) using a computerized random-number generator: one in which participants ingested 7 g of corn syrup containing maltobionic acid and another in which participants ingested 7 g of placebo (maltose syrup) group per day for 24 weeks. BMD and bone metabolism parameters were measured by DEXA (dual-energy X-ray absorptiometry method) and a peripheral blood test, respectively, while safety was evaluated via a physical examination, peripheral blood test, urinalysis, assessment of subjective symptoms, and a medical questionnaire.Results: Thirty-three subjects completed the study, except for one subject who discontinued the study halfway, and there were no adverse events related to consumption of the test food. Fourteen subjects were excluded before the efficacy analysis because of conflict with control criteria; the remaining 23 subjects were studied (10 in the Test food group and 13 in the Placebo group). Consumption of corn syrup solids containing maltobionic acid was maintained during the intervention period, and BMD, bone mineral content (BMC), and YAM (young adult mean) values were found to be improved (P < 0.05). No safety concerns were observed during the intervention period.Conclusion: These results indicate that the consumption of corn syrup solids containing maltobionic acid may contribute to the prevention of osteoporosis.
Changes in plasma concentration of flavonoids after ingestion of a flavonoid-rich meal prepared with basic foodstuffs
Authors: Mannen Ryo , Yasuda Michiko T , Sano Ayami , Goda Toshinao , Shimoi Kayoko , Ichikawa Yoko
Published: October 2019

Background: As flavonoids have a variety of functions, such as antioxidant activity, there is growing interest in the development of flavonoid supplements. However, there have been reports of DNA damage due to exposure to flavonoids at high concentrations in rats, which could suggest that a habitual intake of flavonoid supplements may cause toxicity. Therefore, we considered that ingesting flavonoids from a typical meal combined basic foodstuffs are safe because of unlikely to result high concentrations like supplements, and focused on the intake of flavonoids from a typical meal. Thus, this study investigated the absorption of flavonoids in humans after the consumption of a typical meal. Methods: On the first 2 days of the study, seven healthy volunteers were provided with low-flavonoid meals (flavonoid content below the detection limit by HPLC: less than 0.24 mg/meal) three times a day as a washout. A flavonoid-rich meal (40.44 ± 1.49 mg/meal) was then provided for breakfast on the third day. Blood was collected from all volunteers 0, 2, 3, 7, 8, and 9 h after the flavonoid-rich meal was consumed. After enzyme hydrolysis of the plasma, the plasma concentrations of flavonoids aglycone of quercetin, daidzein and genistein were measured using LC-MS. Urine was also collected and pooled 24 h after the flavonoid-rich meal was consumed. Thereafter, the urine was treated with enzyme hydrolysis, and the measurement of urinary flavonoids was performed. Results: Plasma flavonoid peaks were observed 8 h after consumption of the flavonoid-rich meal (quercetin: 4.29 ± 1.46 μM, daidzein: 0.51 ± 0.41 μM, genistein: 0.91 ± 0.73 μM). Furthermore, flavonoids were confirmed to be present in plasma even at 9 h after the intake meal. The urinary recovery of flavonoids was 3.43 ± 1.50% for quercetin, 13.87 ± 6.68% for daidzein, and 16.89 ± 11.40% for genistein. Conclusion: These results suggest that consuming a typical meal that combines a variety of basic foodstuffs delays attainment of the plasma flavonoid peak compared with consuming a single type of food or supplements as previously reported. In addition, the flavonoid urinary recovery were also reduced compared with those previously reported.
Irisin, leptin and adiponectin levels are reduced significantly during fasting
Authors: Alzoughool Foad , Al Hourani Huda , Atoum Manar , Abdelgader Rana , Alanagreh Loai
Published: October 2019

BACKGROUND:

Ramadan fasting involves refraining from food and liquids from the sunrise till sunset for one month yearly; affecting the sleep pattern and duration, physical activity, and meal number and composition leading to biochemical and physiological changes in the body. Irisin, adiponectin, and leptin induce multiple metabolic effects.

OBJECTIVE:

The aim of this study is to examine the effect of the Ramadan fasting on serum levels of irisin, adiponectin, and leptin.

MATERIALS AND METHODS:

A total of sixty healthy students (43 females and 17 males) were recruited, 20.9 years mean age, who were fasting for Ramadan were included in this study. Anthropometry, blood samples and physical activity were determined. Lipid profiles were determined using an enzymatic colorimetric method, and serum levels of irisin, adiponectin, and leptin were measured using Enzyme-linked Immunosorbent Assay. All measurements were measured before Ramadan and in the fourth week of Ramadan.

RESULTS:

Subjects experienced a significant increase in LDL was determined during Ramadan vs before Ramadan (142.8 vs. 158.1 mg/dl p = 0.03) along with a significant reduction in leptin, adiponectin and irisin concentration during Ramadan compared to before Ramadan (11.6 vs. 8.6; p = 0.000; 4.42 vs. 3.58; p = 0.022; 33.6 vs. 16.3; p = 0.003). A significant positive correlation was found between physical activity and irisin concentration before Ramadan ( r = 0.338, p = 0.022).

CONCLUSIONS:

Ramadan fasting has significant effects on irisin, adiponectin, and leptin levels. Their levels were significantly reduced during Ramadan while LDL level was increased. Irisin level has a significant correlation with the physical activity of the participants.
Dorsal root ganglion axons facilitate and guide cortical neural outgrowth: In vitro modeling of spinal cord injury axonal regeneration
Authors: Xu Zi-Xing , Albayar Ahmed , Dollé Jean-Pierre , Hansel Gisele , Bianchini Justin , Sullivan Patricia Zadnik , Cullen D. Kacy , Smith Douglas H. , Ozturk Ali K.
Published: October 2019

Background:

Spinal cord injury (SCI) patients represent a heterogeneous group, with injuries ranging from partial compression to complete transection. Patients with complete injuries are unlikely to exhibit recovery and suffer from paralysis as well as the loss of bowel and bladder function. One treatment option is the formation of a bridge through a lesion site, whereby transplanted cells or biocompatible scaffolds guide the regenerating axons across the site of injury. Moreover, the viability of transplanted dorsal root ganglia (DRGs) into rat spinal cord has been previously demonstrated.

Objective:

We aim to demonstrate the feasibility of using DRG axons as a bridging tool to help guide the axonal growth of cortical neurons.

Methods:

Cortical neurons were isolated from embryonic rats and two aggregated populations were cultured at increasing distances in isolation and in a co-culture with DRG explants. Growth rates of the sprouting axons and connections between the two populations were observed over a period of twelve days.

Results:

DRG explants demonstrated the ability to grow robust axonal connections that can connect two explants separated by up to 10 mm, however, CNAs could not achieve connections in distances greater than 2 mm. The co-culture of CNAs with DRG explants facilitated axonal growth between two populations of CNAs at distances they cannot otherwise traverse.

Conclusions:

Our findings support the use of DRG axons to facilitate the growth of cortical neurons in a process of axon-facilitated axon regeneration. We believe these results could have implications for the treatment of SCI.
Dynamic multimodal drawing in school: Exploring technology support of drawing skills development in children with visual impairments
Authors: Szymczak Delphine , Rassmus-Gröhn Kirsten , Hedvall Per-Olof , Magnusson Charlotte
Published: October 2019

BACKGROUND:

Technology is widely used in school to assist students with visual impairments. Drawing with traditional methods is still difficult for those users. In this paper, we present and discuss an evaluation of a haptic and sound interactive drawing program (HIPP).

OBJECTIVE:

The aim of the study was to identify what aspects of the technological aid support the drawing skill development in children with visual impairment.

METHODS:

Interviews, observations and video recordings of use situations were used for data gathering. Our analysis is based on cultural-historical activity theory, and examines the mediation between the child and the object of their activity, their drawings, as well as the roles of teachers, classmates, assistants, and family.

RESULTS:

The haptic and audio drawing program supports the steps (doodling, interpretation, planning, and more intentional drawing) observed in visually-acquired drawing, although possible improvements have also been identified. Observations of the drawing program in use showed that its mix of dynamic multimodal interaction and a stable drawing feedback, enable visually impaired students and sighted teachers to jointly access a shared representation.

CONCLUSIONS:

Successful long-term use, together with the presented results of our analysis show how multimodal dynamic and stable interaction can successfully support drawing activities.
A filosofia alemã de 1840 a 1900
Authors: Santini Guilherme José
Published: October 2019

Resenha do livro:BEISER, Frederick. Depois de Hegel: a filosofia alemã de 1840 a 1900. Trad. Gabriel Ferreira. São Leopoldo: Editora Unisinos, 2017.
Immunophenotypic features of leukemic stem cells and bulk of blasts in acute myeloid leukemia
Authors: Ivanivska T.S. , Sklyarenko L.M. , Zavelevich M.P. , Philchenkov A.A. , Koval S.V. , Polishchuk A.S. , Gluzman D.F.
Published: October 2019

Summary. According to the modern concept, leukemic stem cells (LSC) in acute myeloid leukemia (AML) are distinct from the bulk of leukemic cells in bone marrow and peripheral blood of AML patients. Nevertheless, LSC are responsible for managing all the hierarchy of the bulk of leukemic blast populations. This mini-review provides brief information on the distinctive features of LSC and blast cells in cytologically recognized types of AML. The study of different phenotypes of LSC and blast cells in AML with the aid of up-to-date flow cytometric techniques is important both for the deep insight into the mechanisms of leukemogenesis and development of novel strategies of target therapy. The urgent need for extending the diagnostic panel of monoclonal antibodies used for diagnosing AML is beyond doubt.
ANALISIS KESEIMBANGAN TERMAL SISTEM PENDINGIN MESIN PEMBANGKIT LISTRIK ORC (ORGANIC RANKINE CYCLE) KAPASITAS 500 kW
Authors: Maulana Yahya , Gaos Yogi Sirodz , Wiradinata Irvan
Published: October 2019

Sistem pendingin Organic Rankine Cycle (ORC) merupakan komponen sistem pendingin yang sangat penting. Sistem ini terdiri dari kondensor, dry cooler, dan pompa yang berfungsi untuk memaksimalkan efisiensi pada sistem ORC. Jenis kondensor yang digunakan yaitu jenis one shell one pass tube fluida yang juga digunakan pada sistem pendingin, n-pentane (sebagai fluida panas) dan air (sebagai fluida dingin). Penelitian ini bertujuan untuk mendapatkan keseimbangan termal pada kondensor, dry cooler, dan pompa serta  mendapatkan hasil perhitungan analisis termal pada laju perpindahan panas fluida n-pentane dan fluida air pendingin pada kondensor, dry cooler, dan pompa ORC 500 kW. Proses pendinginan pada sistem pendingin ORC pada dry cooler telah mencapai temperatur pendingin optimum pada nilai temperatur 25°C sampai 35°C. Hal ini ditunjukkan pada nilai temperatur pendingin dry cooler berkisar pada temperatur 31°C sampai 32°C. Keseimbangan energi pada laju perpindahan panas n-pentane Qdc = 2,34 kW sedangkan laju energi yang diterima fluida air dingin yaitu Qc = 1,70 kW dan laju energi pada dry cooler Qeq = 0,64 kW menurut perhitungan diagram p-h.