bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular features of thyroid cancer in children
Authors: Baeva Oksana K. , Kiseleva Natalya S. , Biktasheva Elina E. , Gazizova Liliya R. , Fimina Margarita I. , Akhmetova Ilyuza I. , Kazakova Anastasiya E. , Yadrenkin Kirill D. , Dautova Darya A. , Grishnikova Anastasiya D. , Gaisina Elvira D. , Galiaskarova Ilina A.
Published: September 2023

Background. Malignant neoplasms of the thyroid gland are the most common endocrine malignant neoplasms in the children’s age group. Unlike adults, who most often have BRAF and RAS mutations, children have chromosomal displacements. The relevance is explained by the lack of comprehensive studies on thyroid cancer in children in the Russian-language literature.

The aim of the study is — to summarize and systematize the literature data on the molecular features of thyroid cancer in children.

Materials and methods. The authors conducted a search for publications in the PubMed electronic database using the following algorithm: Molecular AND Thyroid cancer AND pediatrics. We found 451 publications, and after reviewing the annotations, 111 studies describing the molecular features of thyroid cancer in the pediatric population were included in the review. Publications were excluded due to duplication and inconsistency with the subject of this study.

Results. Instead of point mutations of BRAF and RAS, characteristic of adults, regardless of radiation status, chromosomal displacements are more common in children. Re-arrangement of RET/PTC genes is the most common, followed by BRAF fusions. Mutations of the TERT promoter, which are markers of the aggressive course of the disease in adults, are rare in children. DICER1 mutations appear to play a key role in pediatric cases of follicular and papillary thyroid cancer. Medullary thyroid cancer (MTC) in children requires the exclusion of multiple endocrine neoplasia syndrome (MEN type 2). Tumors originating from follicular cells other than MTC can rarely be familial. Literature data on the role of microRNA as a biomarker in thyroid carcinomas in children is currently limited.
Wittgenstein and Stenlund on Mathematical Symbolism
Authors: Sætre Martin Gullvåg
Published: September 2023

In recent work, Sören Stenlund (2015) contextualizes Wittgenstein’s philosophy of mathematics as aligned with the tradition of symbolic mathematics. In the early modern era, mathematicians began using purely formal methods disconnected from any obvious empirical applications, transforming their subject into a symbolic discipline. With this, Stenlund argues, they were freeing themselves of ancient ontological presuppositions and discovering the ultimately autonomous nature of mathematical symbolism, which eventually formed the basis for Wittgenstein’s thinking. A crucial premise of Wittgenstein’s philosophy of mathematics, on this view, is that the development of mathematical concepts is independent of any ontological implications and occurs in principle without normative connections to empirical applicability. This paper critically examines this narrative and arrives at the conclusion that Stenlund’s view of mathematical progress is in stark contrast to the later Wittgenstein’s writing, which emphasizes links between symbolisms and their applications.
Improving the efficiency and effectiveness of project activities at the municipal level
Authors: Kapustina Nadezhda , Korneva Galina , Dasni Dasan
Published: September 2023

Within the framework of the presented article, the author explores an issue that is directly related to the specifics of the implementation of project activities. In the center of his attention is the problem of increasing the effectiveness of this type of activity carried out at the municipal level. At present, project activities are becoming more and more common, which necessitates the development of a mechanism aimed at assessing efficiency, effectiveness and cost-effectiveness. First of all, the author pays attention to the consideration of these concepts, their clear differentiation, and also studies them from the point of view of the national standard of the Russian Federation. The effectiveness of project activities can only be assessed if there are clear target indicators defined at the initial stage of project planning, which, in turn, are divided into quantitative and qualitative ones. In this regard, it is important to carefully analyze the project at an early stage. Only in this case, possible risks can be minimized and both time and material resources spent on the project implementation can be saved. As for the effectiveness of project activities, it involves the correlation of results, project costs with the goals of the interests of the state and the population. For a more complete understanding of the issue under consideration, the project activity is also considered in the article using the example of Slobodsky, a city in the Kirov region. The results of evaluating the effectiveness of the implementation of municipal programs of the city are presented. Based on the results of consideration of the issue, both at the theoretical and practical levels, the author formulated a number of recommendations to improve the efficiency and effectiveness of project activities at the municipal level.
Economic sanctions as the reasons for the destabilization of the automotive market in Russia
Authors: Kondratiev Anton , Lazarev Borislav , Abdulragimov Israil
Published: September 2023

Within the framework of this article, the features of the development of the Russian automotive market in the conditions of sanctions pressure from a number of states are analyzed. According to the author, the automotive industry is important in the context of the development of the real sector of the economy. In this regard, it is largely subject to state regulation. Thus, the main role of the state is to determine the extent to which foreign companies enter the domestic market, including the construction of manufacturing enterprises and the creation of various types of support for domestic companies. The automotive industry has undergone particular changes over the past year due to the imposition of sanctions after the start of the NWO. A large number of companies also either completely left the market or suspended their activities, which led to an increase in prices for cars remaining with dealers, because new cars are not supplied and dealers, due to low supply, cannot meet demand. However, despite this fact, it is impossible to say that the sanctions had only a negative impact on the automotive industry. For example, the author notes that in 2022 there was an increase in demand for cars from Chinese manufacturers such as Chery, Geely, Haval, which, in turn, has a positive effect on trade relations between Russia and China. In addition, the article provides statistical data on the dynamics of prices for the most popular cars in Russia, as well as for BMW models after February 24th. The final part of the article is devoted to the conclusions formulated by the author regarding the impact of sanctions on the prospects for the Russian automotive market.
Possibilities of applying the Due Diligence procedure in an economic entity
Authors: Abdulkarimova Aminat , Koroleva Lyudmila
Published: September 2023

This article discusses the possibility of practical application of the Due Diligence procedure on the example of one of the Russian companies. The company "Packaging Solutions" LLC was chosen as an economic entity. At the beginning of the article, the author provides the basic data of the organization, its staff, main activities, property. Further, more detailed information about the type of activity of the organization is disclosed, as well as the fact of the company's special attitude to issues of economic security. The author reveals the concept of economic security, and also considers factors that may affect the economic security of an individual economic entity or the country as a whole. In more detail, the article discusses external factors that affect the economic security of individual organizations. After establishing the general principles for maintaining economic security in organizations, the author proceeds to consider economic security in Packaging Solutions LLC. This organization has features of economic activity that positively distinguish it from other companies in terms of economic security of an economic entity. The author considers the coefficient of financial independence of the organization, which positively characterizes the economic security of the organization, also mentions the presence of a patented trademark, which is an advantage in the modern market, since its own trademark provides recognition of the company and gives it legal protection. The article also pays attention to ensuring economic security in the field of contractual relations, building relationships with customers, information security of the company, and the personnel policy of the organization. After considering the positive aspects of the economic security of this company, the author proceeds to highlight the shortcomings of economic security. To establish the shortcomings of the organization's activities, the author analyzes its indicators. Based on the results of the analysis, the author identifies the following threats to the economic security of the organization: high competition in the market, unstable financial condition, participation of the company in court as a defendant. At the end of the work, the author gives possible solutions to improve the efficiency of the company's economic security system.
The meaning and role of personnel loyalty in the context of ensuring the economic security of an economic entity
Authors: Shabanova Madina , Turgaeva Aksana
Published: September 2023

In modern conditions of business management, one of the key factors in ensuring economic security is staff loyalty. In the work, the author emphasizes that the lack of staff loyalty can significantly harm the business entity. First of all, this can lead to the leakage of confidential information, a decrease in product quality, a negative impact on the company's reputation, and even unprofitability. On the other hand, the presence of staff loyalty can have a positive impact on the financial condition of an economic entity. Employees who feel loyalty to the company are more likely to improve their work efficiency and improve product quality. This, in turn, can lead to increased profits and strengthen the company's position in the market. According to the author, the loyalty of the staff is an integral element in ensuring the economic security of an economic entity. To create employee loyalty, it is necessary to create comfortable working conditions, conduct staff training and development, and maintain corporate culture and values. The commitment of the company's employees and their loyalty can be created not only through the improvement of working conditions, but also through the optimization of management. The management of the company should be transparent, honest and fair, while not only rewarding those who show good results, but also helping those who are experiencing difficulties to improve their work. The author notes that the company should provide its employees with opportunities for professional growth, organize trainings and seminars, and encourage participation in conferences and exhibitions. This will help employees expand their knowledge and skills, as well as see that their work is valued and required in the organization.
Economic aspects of assessing the loyalty of the personnel of an economic entity
Authors: Galstyan Satenik , Rogulin Yuriy
Published: September 2023

One of the important tasks of personnel management is to determine the level of employee loyalty to the company, which allows assessing the level of staff satisfaction and responding to emerging problems in a timely manner. According to the author, staff loyalty is an integral part of the successful functioning of any enterprise, because it is the employees who ensure its efficiency and competitiveness in the market. Various methods are used to determine the degree of employee loyalty, including surveys, interviews, questionnaires, observation of employee behavior, analysis of certain indicators (for example, staff turnover or the frequency of painful absences). Each method has its advantages and disadvantages, and the choice of the appropriate one depends on the goals and capabilities of the company. Surveys and questionnaires allow you to quickly obtain information about the opinion of employees but may not be detailed enough and do not allow you to ask clarifying questions. Interviews give a more complete picture of the opinion of employees but require more time and resources. Observing the behavior of employees can provide information about how they feel about work, but it does not always reveal the reasons for negative or positive behavior. Analysis of indicators can show what problems exist in the company, but it is not always objective enough and does not take into account the individual characteristics of employees. To achieve the best results, an integrated approach is used, which includes several methods. In addition, it is important to take into account feedback from employees and use the information received to improve working conditions and increase staff satisfaction. The author notes the importance of understanding that the level of employee loyalty to the company directly affects its efficiency and competitiveness in the market. Therefore, regular determination of the level of loyalty and the use of the information received to improve working conditions and increase employee satisfaction are necessary conditions for the successful functioning of any enterprise.
Analysis of project management in the framework of entrepreneurial activity
Authors: Suleymanov Arslan , Rogulin Yuriy
Published: September 2023

This publication is devoted to the analysis of the features of entrepreneurial activity in a competitive environment, which, in turn, carries a number of risks. The higher the level of competition in the market, the higher the level of risks that it carries with it for entrepreneurial activity. Every entrepreneur, in order to remain competitive in the market, must deal with emerging risks. The author notes that the growing effects of globalization and technological innovation create fundamental challenges for many companies and business processes. However, the world is becoming more and more competitive because barriers to entry are decreasing. The article highlights the most common risks faced by entrepreneurs in different countries. Particular attention is paid to the analysis of the features of the implementation of projects in the framework of entrepreneurial activities. According to the author, the most important parameters in project management are content (product and volume), time, quality, budget (finances and those resources that can be purchased within the allocated funds). Further in the article, attention is paid to the approaches applied to project management. In particular, functional, systemic, process and situational approaches are considered. The author emphasizes that planning and control are important for optimizing project resources. With the development of market relations, a large number of new ways to finance projects have appeared and, theoretically, the possibilities for raising funds have expanded. In the final part of the article, the author formulates the conclusion that in order to minimize risks in the implementation of projects, entrepreneurs need to develop action plans for various situations, train employees to prevent and prevent certain risks, and develop control tools.
O EXÍLIO TROPICAL: VIDAS FORÇADAS DE ARTISTAS BRASILEIROS NO EXTERIOR
Authors: Madeira Thiago Matheus
Published: September 2023

Este trabalho trata da relação entre arte e política, especificamente no período da ditadura militar no Brasil. Seu propósito de pesquisa visa compreender as relações entre Estado autoritário e produção artística, enquanto condição de pressão política. No período de ditadura brasileira nos anos 70 e do surgimento de movimentos artísticos-sociais, tais como o Tropicalismo e o Cinema Novo, o Estado atuou enquanto agente controlador e censor, e a arte, por sua vez, como forma de resistência, o que resultou nos exílios dos cantores Caetano Veloso e Gilberto Gil para Londres, na Inglaterra, fatos estes que constituem os casos de estudo desta dissertação. Procura-se, ainda, compreender as influências e as alterações decorrentes do exílio que afetaram a obra desses artistas. Para tanto, é estabelecida uma periodização histórica, bem como é analisado o conceito de exílio e seu impacto na produção artística dos referidos autores. Neste sentido, nota-se, inicialmente, que, no primeiro período, isto é, no pré-exílio, as obras de ambos, consideradas de caráter subversivo à ordem, promoveram um importante debate no contexto social do país. Após o segundo período, o de prisão e exílio em Londres, suas produções refletiram uma maior introspecção, seguida também de uma ampliação de sua liberdade experimental, promovida pelo novo contexto social em que estavam inseridos. Finalmente, no terceiro período, o de retorno de ambos os artistas ao Brasil, a síntese e a consolidação do contato com influências políticas e culturais que tal cidade global propiciou, integram-se com a retomada de suas raízes.
THE ONSET OF CONVECTION IN THE WOODING PROBLEM WITH ANISOTROPIC PERMEABILITY
Authors: Islam Shamima , Ferdows M. , Rees Andrew , Bassom Andrew P.
Published: September 2023

We consider the Wooding problem, namely the onset of convection in a semi-infinite saturated porous medium with uniform downward suction into a horizontal and uniformly hot bounding surface. In particular we shall begin to examine the stability properties of convection for the case of a mechanically anisotropic porous medium. A linearized stability analysis is performed and the partial differential system of governing equations is transformed into an ordinary differential eigenvalue problem for the critical Darcy-Rayleigh number, Ra, as a function of wavenumber, k, and the anisotropy ratio, ξ. The eigenvalue problem is solved numerically through the use of the MATLAB routine BVP4C. Neutral curves are presented and the critical parameters are found as a function of ξ. It is found that both the critical Darcy-Rayleigh number and wavenumber decrease with increasing values of ξ. An asymptotic analysis is also presented for ξ >> 1 where we find that Rac ~ 3.67049 + O (ξ-1/2) and kc ~ 0.96565ξ-1/4.
Prediction of rural tourism suitability based on multi-dimensional evaluation model
Authors: Li Yue
Published: September 2023

There is an increased focus on how to improve tourism quality in rural areas. To provide reference and guidance for both tourists and tourism departments, a multi-dimensional tourism suitability model is proposed. Meteorological, travel and other data related to a tourism area were analysed, and a tourism suitability evaluation architecture model was developed. From February to September, when temperature fluctuations were more clearly defined, the prediction accuracy of the model was higher, while the test results of the root mean square error and other indicators of the model in meteorological prediction were good. The model had the highest prediction accuracy of 96.8% under multi-dimensional conditions. The model could provide accurate guidance for tourists to choose travel dates and destinations, further promoting rural tourism.
İŞ YERİNDE İYİLİK HALİ ÖLÇEĞİNİN KISA FORMUNUN GEÇERLİLİK VE GÜVENİLİRLİK ÇALIŞMASI
Authors: ŞAHİN Dilek , ARSLAN Tuba
Published: September 2023

Bu çalışmanın amacı, Smith & Smith (2017a) tarafından hazırlanan İş Yerinde İyilik Hali Ölçeğinin Kısa Formunu (A Short Questionnaire To Measure Wellbeing At Work (Short-SWELL)) sağlık çalışanlarının iş yerinde iyilik halini ölçmek için Türkçeye uyarlama, geçerlik ve güvenirlik çalışmalarını yapmaktır. Araştırma grubu bir devlet hastanesindeki 452 adet sağlık çalışanından oluşmaktadır. Araştırma bir ölçek uyarlama çalışması olduğu için öncelikle dil geçerliği, kapsam geçerliliği, yapı geçerliği ve güvenirlik analizleri incelenmiştir. Ölçeğe ait Açımlayıcı Faktör Analizi sonuçlarına göre ölçeğe ait toplam varyansın %67,11’ini açıklayan iki faktörlü bir yapı elde edilmiştir. Doğrulayıcı Faktör Analizi, uyum indekslerine bakıldığında CMIN/DF=3.885, RMSEA=0,08, NFI=.953, CFI=.964, AGFI=.910, GFI=.951 olarak bulunmuştur. Ölçeğin güvenirliğini belirlemek için yapılan toplam iç tutarlılık katsayısı ise 0.798 bulunmuştur. Araştırma kapsamında İş Yerinde İyilik Hali Ölçeğinin Kısa Versiyonunun Türk kültüründe sağlık çalışanlarının iş yerinde iyilik hali düzeyini ölçmek için kullanılabilecek bir ölçüm aracı olduğu sonucuna ulaşılmıştır.
ORTA KADEME YÖNETİCİLER GÖZÜYLE YÖNETİCİ VE YÖNETİCİLİK BECERİLERİ
Authors: ÖZKANAN Arzu
Published: September 2023

Yönetim ve yöneticilik becerileri denildiğinde ilk akla gelen üst kademe yöneticiler olmaktadır. Konumları itibariyle hem birer çalışan hem de birer yönetici olan orta kademe yöneticilerin göz ardı edilen yöneticilik pozisyonları bu çalışmanın kapsamını oluşturmaktadır. Bu çalışma ile yönetici ve yöneticilik becerilerine orta kademe yönetim gözünden bakmak amaçlanmaktadır. Orta kademe yöneticilerin hem birer ast olarak yöneticilerini gözlemleyebilmeleri hem de birer yönetici olmaları nedeniyle yöneticilik becerilerine iki farklı açıdan değerlendirmeleri mümkün olmaktadır. Orta kademe yöneticilerin yöneticilik ve yönetsel beceriler konusundaki görüşlerini belirleme amacı güden çalışma nitel metot ile dizayn edilmiştir. Bu amaçla yürütülen çalışmada veriler üniversitelerde akademik birimlerde görev yapan 24 Enstitü/Fakülte/Yüksekokul Sekreteri ile yarı yapılandırılmış görüşme formu aracılığıyla yürütülen görüşmeler ile elde edilmiştir. Bulgulara göre katılımcılar üst kademe yöneticilerinden en fazla adaletli olmalarını beklemekte ve insan ilişkileri becerileri ile donatılmış olmaları gerektiğini belirtmektedirler. Kendilerinin de yer aldığı orta kademe yöneticilerde ise iletişimin güçlü olmasının gereğine vurgu yapmakta ve yine insan ilişkileri becerilerine ağırlık vermektedirler. Bunun yanı sıra kendilerinin engellendiğini düşünmekte ancak bu engelin yine kendilerinden kaynaklandığını ifade etmektedirler. Bu doğrultuda yaptıkları iş itibariyle insan ilişkileri becerilerinin önemi açıkken kendilerini bu anlamda geliştiremedikleri de görülebilmektedir. Çeşitli eğitimler ve özellikle yönetici geliştirme uygulamaları ile orta kademe yönetimin güçlendirilmesi gerekmektedir.
TÜRKİYE'DE MALİ YERELLEŞMENİN BÖLGESEL GELİR EŞİTSİZLİĞİ VE YOKSULLUK ÜZERİNE ETKİLERİ
Authors: ÇUKUR Asuman
Published: September 2023

Literatürde gelirin yeniden dağılımına ilişkin politikaları merkezi yönetimin mi yoksa yerel yönetimin mi daha etkin uygulayacağına dair tartışmalar sürerken bu kapsamda mali yerelleşmenin gelir eşitsizliği ve yoksulluğa etkilerinin özellikle son dönemde sıklıkla araştırılan bir konu olduğu görülmektedir. Bu çalışmada Türkiye’de mali yerelleşmenin gelir eşitsizliği ve yoksulluğa etkileri 2014-2020 yılları için 26 alt bölgeye ait veriler kullanılarak literatüre dayalı 6 farklı modelle panel veri analiz yöntemiyle incelenmiştir. Mali yerelleşmenin harcama ve gelir yerelleşmesinin yanı sıra yerel mali özerklik göstergeleriyle de ölçüldüğü bu araştırmanın sonuçları gelir yerelleşmesinin gelir eşitsizliğini azalttığına dair güçlü kanıtlar bulurken mali yerelleşmenin bölgesel yoksulluğa etkilerine dair zayıf kanıtlar bulmuştur. Sonuçlar ülkemizde hem harcama hem de gelir yerelleşmesinin refah etkileri açısından tekrar gözden geçirilmesi gerektiğine işaret etmektedir.
Constitutional and Criminal Law Protection of Human and Civil Rights and Freedoms
Authors: Minnikes Ilia
Published: September 2023

The article presents an inter-branch study of the problems of constitutional law and criminal law protection of human and civil rights and freedoms. The analysis of current Russian legislation is used to determine the objects of legal protection. The concept of legal protection in the general theory of state and law is also the basis of branch legislation which takes into account the specific features of the object of legal regulation in constitutional and criminal law. The subject of the research is articles of Chapter 19 of the Criminal Code of the Russian Federation «Crimes against the Constitutional Rights and Freedoms of Man and Citizen». The main methodological instrument is the «safety index» introduced by the scholars of the Ural law school. The author shows its significance for Russian constitutional and criminal law and its role in protecting rights and freedoms. The hierarchy of values is presented from the standpoint of their criminal law protection. It is concluded that constitutional human and civil rights and freedoms as objects of criminal law protections have lower «safety indices» and insufficient criminal law protection compared to other legal values. The author analyzed the changes of the lawmakers position regarding constitutional rights and freedoms that are objects of criminal law protection, and the dynamics of this process. As legal protection greatly depends on the sanctions determined by the lawmakers, the question of their proportionality is raised. Alternative methods of researching this problem in Russian and foreign legal theory are presented. The sanction of the criminal law norm is then viewed not only as an element of the legal norm, but also within the system of external and internal connections from the standpoint of its place in the mechanism of criminal law regulation. The author touches upon the problem of constructing criminal law sanctions while taking into account the axiological aspect. In foreign research, the so-called «price theory» stands out, it understands law as a tax on behavior. Besides, the «localization coefficient» illustrates the experience of using the methodology instruments of other fields of research, including non-humanitarian ones, to study legal matters.
Deep learning-based object detection for smart solid waste management system
Authors: Meron Desta , Tagel Aboneh , Bisrat Derebssa
Published: September 2023

Currently in Ethiopia, pollution and environmental damage brought on by waste increased along with industrialization, urbanization, and global population levels. Waste sorting, which is still done improperly from the household level to the final disposal site, is a prevalent issue. Real-time and accurate waste detection in image and video data is a crucial and difficult task in the intelligent waste management system. Accurately locating and classifying these wastes is challenging, particularly when there are various types of waste present. So, a single-stage YOLOv4-waste deep neural network model is proposed. In this study, a deep learning algorithm for object detection using YOLOv4 and YOLOv4-tiny is trained and evaluated. A total of 3529 waste images are divided into 7 classes, which include, cardboard, glass, metal, organic, paper, plastic, and trash. Each model uses three various inputs throughout the testing phase, including input images, videos, and webcams. Experiments with hyper-parameters on subdivision values and mosaic data augmentation were also done in the YOLOv4-tiny model. The outcome demonstrates that YOLOv4 performs better than YOLOv4-tiny for object detection specifically for waste detection. The outcome shows that YOLOv4 performs better than YOLOv4-tiny for object detection, even if YOLOv4-tiny’s scores are higher in terms of computing speed. The best results from the YOLOv4 model reach mAP 91.25%, precision 0.91, recall 0.88, F1-score 0.89, and Average IoU 81.55%, while the best YOLOv4-tiny results are mAP 82.02%, precision 0.75, recall 0.76, F1-score 0.75, and Average IoU 63.59%. This research also proves that the models with smaller subdivision values and using a mosaic have optimal performance.
The quality of medical and social expertise of the contingent of children with disabilities in the City Children’s Polyclinic
Authors: Shapovalov KA , Shapovalova PK , Makarova NM , Gusarova SA , Semyannikova NA , Dobrisavlevich EN , Avtushina KA
Published: September 2023

The quality control of the provision of the State Service of passing the Medical and Social Examination (SS MSE) is carried out as part of the implementation of a set of measures to achieve the indicators of the Decree of the President of the Russian Federation (RF) No. 601 (assessment of the level of satisfaction of citizens with the quality of state services). The purpose of the study was to determine the quality of the provision of SS MSE and possible reserves for its improvement. The analysis of 566 referrals for the passage of the SS MSE of a medical organization, submitted by official representatives of children - patients of the state budgetary healthcare institution of the Republic of Komi “Syktyvkar Children’s Clinic No. 3”, and a survey of official representatives of children who were diagnosed with disability, according to the questionnaire for assessing the level of satisfaction of citizens with the quality of the provision of SS MSE. Methods of analysis included: analytical and comparison. The following techniques were used for the analysis: grouping, absolute and relative values, average values, detailing, and generalization. The reliability of the results obtained was assessed by calculating the Student’s coefficients. The depth of the study was 3 years. Experts now have the opportunity to determine disability for children with severe persistent pathology not for 1 - 2 years, but for 10 - 15 years, in some cases, according to indications, and more, up to the age of 18. Some children and adolescents are permanently disabled. This significantly reduces the annual burden for patients to undergo examinations by medical specialists, and many clinical diagnostic and laboratory tests. At the same time, an annual examination by specialists of medical and social expertise to correct the individual rehabilitation/habilitation program of patients is not excluded.
Kızılçam kabuk taneni ile modifiye edilmiş üre formaldehit tutkalının özellikleri
Authors: YEŞİLTEPE Kadir , GÖNÜLTAŞ Oktay
Published: September 2023

Bu çalışmada kızılçam kabuk taneni ile modifiye edilmiş üre formaldehit tutkalının performans özellikleri ortaya konulmuştur. Kızılçam kabuğundan ekstraksiyon ile tanen elde edilmiş ve bu tanen üre formaldehit tutkalına, tutkal katı maddesine oranla %5-50 arasında katılarak modifiye üre formaldehit tutkalı elde edilmiş, bu tutkalın performans özellikleri ortaya konmuştur. Modifiye tutkal örneklerinin viskozite, katı madde miktarı, jel süresi, pH ve tutkalda serbest formaldehit tayini yapılmıştır. Tüm tutkal örneklerinin ıslak ve kuru dayanım değerlerini ortaya koymak için kayın kaplama kullanılarak Lap Shear çekme dayanımı testleri gerçekleştirilmiştir. Aynı zamanda modifiye tutkalların FTIR analizleri ve yapışma hattının mikroskobik görüntüleri alınarak analiz edilmiştir.

Modifiye edilmiş tutkal grupları arasında tanen kullanım oranı arttıkça tutkal viskozite ve jelleşme süresinin arttığı görülmüştür. Tanen oranı %15 olan U4 modifiye tutkal grubunda jelleşme süresi 340 sn. olarak kaydedilmiştir. Modifiye edilmiş tutkalın serbest formaldehit tayini sonuçları incelendiğinde tanen oranının artmasıyla tutkaldaki serbest formaldehit miktarında azalma meydana gelmiştir. En düşük serbest formaldehit değeri U5 örneğinde %0.32 olarak belirlenmiştir. Modifiye tutkal örneklerinde belirlenen 2972 ve 2901 cm-1 piklerinde keskinleşme ve belirginleşme, 1123 cm-1 bölgesindeki tepe noktası kayması ve pik genişlemesi ile örneklerdeki kimyasal modifikasyon ve yeni bağların oluşumu ortaya konulmuştur.
HEK3/LINC01509 Library Preparation v1
Authors: Chu Mathew
Published: September 2023

Library preparation for HEK3 recording site (LINC01509) using PCR and digestion.
A regulação de alimentos de origem animal no Brasil à luz da teoria processual administrativa da regulação
Authors: Soares Ferreira Ismael , Iorio Aranha Márcio
Published: September 2023

Objective: to analyze the regulation of food of animal origin carried out by the Brazilian Health Surveillance Agency (Anvisa, in Portuguese) and the Ministry of Agriculture, Livestock and Food Supply (MAPA, in Portuguese) from the perspective of a process-oriented approach to regulation, with a specific emphasis on cases involving chemical substances in food of animal origin. Methods: this research conducted two case studies. The first case study examined Anvisa's normative acts regarding residues of veterinary drugs in food of animal origin. The second case study analyzed MAPA's decision to discontinue routine official analyses of water samples in the animal food industry. The research approach was qualitative, focusing on investigating the institutional and normative composition of Anvisa and MAPA from the perspective of a process-oriented approach to regulation. Results: the analysis revealed that Anvisa has successfully implemented mechanisms consistent with a process-oriented approach to regulation, including regulatory autonomy, functional stability of regulatory bodies, and administrative procedures to promote social participation. On the other hand, MAPA's institutional-legal environment exhibits less autonomy and formally adopted procedural elements consistent with a process-oriented approach to regulation since 2015. However, there is a concern that these elements might be eliminated when drafting internal regulations. Conclusion: the Brazilian regulatory model divides animal food regulation between two agencies, potentially resulting in decisions that overlook the public interest and social participation. This is evident in the normative production of MAPA, despite their formal adoption of good regulatory practices.
Received: 11/04/23 | Accepted: 18/05/23
Direito à saúde, tratamentos experimentais e indústria farmacêutica: breves anotações
Authors: Barbosa Ramos Edith Maria , De Sena Jaqueline Prazeres , Do Rosário Pedro Trovão
Published: September 2023

Objective: to understand the excess of judicialization in Brazil and seek some justifications that led to the state of the art. Methods: an inductive research method was used, which involved conducting a bibliographic survey and documentary analysis of data released by the National Council of Justice and, in addition, data extracted from the institutional website of the National Supplementary Health Agency. Results: the judicialization of health has presented a predominantly individual aspect, which aggravates the reach of macrojustice and community care. In addition, the structural difficulties of the Unified Health System become increasingly evident. The judicialization of health can be perverse from the point of view of the excess of granting emergency guardianships, the priority of individualized justice, the prominence of microjustice; elements that undermine the functioning of the health system as a whole. Conclusion: the pharmaceutical industry plays an intense role in the drug incorporation process. However, the complexity and delay in the procedural stages of incorporating these new technologies often result in legal demands that result in controversial decisions that are not always correct. This entire design ends up triggering pressure on the competent incorporation body, misunderstandings about the functioning of the SUS and strengthening microjustice.
Received: 07/07/23 | Accepted: 21/08/23
Teoria Sistêmica, subsistema do Direito e o novo paradigma da Saúde Única
Authors: Delduque Maria Célia , Nobre Sergio , Silva Oswaldo José Barbosa
Published: September 2023

Objective: to discuss the new One Health paradigm in the light of Niklas Luhmann’s Systemic Theory and the performance of the Law subsystem in view of the interconnections of the approach. Methodology: this was an unprecedented critical essay, using Luhmanian theory and the new concepts of single health. Results: Luhmann’s theory of social systems enables the subsystem of Law, in its autopoiesis, to understand and begin to operate with the new integrated approaches to human health, animal health and the environment. Conclusion: the Law subsystem can incorporate the new paradigm into its internal communication, recognizing the future single health legislation.
Received: 21/08/23 | Accepted: 01/09/23
Swaying Individuals’ Privacy Concerns via Amplifying versus Diminishing Counter Argument
Authors:   Eastern Illinois University, Wang Nan , Rieger Louisa ,   Eastern Illinois University
Published: September 2023

Background: Though limited, research has found that individuals' privacy concerns could be swayed by counter argument. This study investigated the swaying influence of amplifying vs. diminishing argument (i.e., counter argument seeking to increase or decrease privacy concerns) on individuals’ privacy concerns and the moderating influences of level of sensitivity and privacy-related knowledge. Method: Data was collected using online survey and respondents were college students enrolled in a Midwestern university. 215 students participated in the survey, resulting in 180 completed responses; two factors (survey competition time and response consistency for reversely-coded items) were used to screen response quality and 90 responses were kept. Data was analyzed using univariate analysis. Results: Results suggest that the swaying influence of counter argument depends on the level of sensitivity—the swaying influence is greater when individuals are presented with amplifying (diminishing) argument for a highly (less) sensitive issue/scenario. In addition, although the swaying influence is smaller for those with high privacy knowledge in general, it is not necessarily easier to sway those with low privacy knowledge. Instead, those with low privacy knowledge are more likely to get stuck or trapped in their existing privacy beliefs when facing privacy argument inconsistent with their existing beliefs, and are more likely to be provoked or stirred up when facing argument reinforcing their existing beliefs. Conclusion: Findings suggest that when processing privacy argument, individuals show confirmation bias and tend to “go with their initial assessments”. This is especially true for those with low privacy knowledge. When facing privacy related argument, individuals with low privacy knowledge behave the opposite of how magnets work—while magnets’ opposite poles attract each other and similar poles repel, individuals with low privacy knowledge embrace argument consistent with their existing beliefs and repel/reject argument inconsistent with their existing beliefs.
Exploring the Synergy Between Financial Technologies and Financial Inclusion: What We Know and Where We Should Be Heading?
Authors:   Symbiosis Centre for Information Technology, Symbiosis International (Deemed University), Bharathi S. Vijayakumar , Perdana Arif ,   Monash University, Kulkarni Mugdha Shailendra ,   Symbiosis Centre for Information Technology, Symbiosis International (Deemed University)
Published: September 2023

Background: Innovative financial technologies (fintech) are gradually changing how financial transactions and processes are conducted. The adoption of fintech not only benefits the financial sector but can also have a broader impact on society. Due to their ability to provide customized services to a wide range of stakeholders, fintech is gaining traction and experiencing significant growth. Compared to traditional financial institutions, fintech companies can reach a wider audience and operate more efficiently. In addition to upending traditional financial services, fintech can also provide financial services to marginalized groups. We argue that fintech research and practice should focus on seizing opportunities and addressing challenges related to financial inclusion, especially in emerging markets. Method: We conducted a systematic literature review of 178 articles to understand the relationship between fintech and financial inclusion. Results: Our analysis highlights six fintech research themes: fintech and financial inclusion, fintech adoption and use, fintech and sectoral growth, fintech and lending, and technology shaping the fintech. We also present four future themes (basic, driving, niche, and emerging or declining research) that can accelerate financial inclusion. Conclusions: This study highlights the synergies between fintech and financial inclusion research. This study contributes to existing knowledge in three ways. First, the descriptive analysis maps existing research on fintech and financial inclusion. Second, the qualitative analysis provides a comprehensive overview of how fintech and financial inclusion topics is interconnected. Third, future research areas for fintech and financial inclusion were identified. In general, fintech democratizes financial inclusion for the unbanked and marginalized communities while reducing operating costs. Governments should promote financial inclusion among those most vulnerable and affected by global threats.
Interaction Between Agile Methods and Organizational Culture – A Qualitative Study
Authors:   Finnish Institute of Occupational Health, Känsälä Marja , Tokumaru Norio ,   Kansai University
Published: September 2023

Background: Agile practices have gained popularity in the 21st century. There is also a growing body of research on agile methods. While some earlier research on agile practices and organizational culture exists with the assumption that the optimal combination of agile practices and organizational culture exists, we examine how agile methods and organizational culture interact and are mutually adjusted. Method: To find out how agile methods and organizational culture are related in practice, we conducted 50 semi-structured interviews with software and embedded software developers from five Japanese companies and three software teams from Finland. Results: Adopting agile methods does not necessarily cause convergence of organizational culture toward democratic which seems to be most compatible with archetypal agile practices. Agile methods can be adapted to organizational cultures that are sometimes challenging to modify. We demonstrate that companies tried to fit agile practices into hierarchical organizational cultures, demonstrating that organizational culture can occasionally be viewed as an exogenous variable influenced firm-, product-, and industry-specific features. Also, it is possible to transform organizational cultures to democratic. The examples demonstrate how companies alter their culture in part through HRM techniques. It should be noted, however, that these efforts to conform to culture can have some restrictions. Conclusion: There is not a single ideal combination of agile methods and organizational culture, despite what some earlier studies suggested. The results show how organizational culture and agile methods interact and adapt to one another in different ways. According to several earlier studies, different organizational cultures may support different facets of agile methods. They do not presuppose organizational culture diversity; in that it goes beyond the notion of a one-to-one relationship between agile methods and democratic organizational culture. While implementing agile practices in various organizational cultural contexts, practitioners must consider how agile methods and organizational culture are interconnected.
Mobile Curated News Readers’ Intention to Read Full-length Articles: Focusing on Heuristic and Systematic Factors
Authors:   Dalhousie University, Puri Malti , Lee Kyung Young ,   Dalhousie University, Deval Hélène ,   Dalhousie University, Deng Qi ,   Dalhousie University, Gonzalez Paola ,   Dalhousie University, Song Young Ho ,   University of Windsor
Published: September 2023

Background: Mobile curated (shortened) news is now increasingly popular. Each curated news article is accompanied by a link that readers can click to read the full-length article on the news provider’s website. To date, little empirical research has examined the factors that influence mobile newsreaders’ intentions to read full-length articles from their curated short forms. To address this gap, this study employs the Heuristic-Systematic Model (HSM) of information processing and examines: 1) how the heuristic and systematic factors of online curated news influence newsreaders’ intention to read full-length articles; and 2) how newsreaders’ language proficiency levels moderate these effects. Method: A survey was conducted with 195 participants recruited from Amazon MTurk. The participants first read a sample curated news item developed for this study and then filled out the questionnaire to measure the variables of interest. To test the hypotheses, a partial least square method was used with SmartPLS 4.0. Results: Our results showed that people have stronger intentions to read full-length articles when they perceive the curated news to have highly relevant information, an attractive title, a credible source, or less understandable information. Furthermore, newsreaders' language proficiency level has a moderating impact on some of these effects. The effects of these factors can be attributed to how they influence newsreaders’ reading behaviors and their heuristic or systematic processing of the curated news. Conclusion: The curated news can be properly designed to motivate newsreaders’ intention to read full-length articles. The findings contribute to the body of knowledge on HSM and mobile news adoption. The findings also provide mobile-curated news service providers and online full-length news media platforms with valuable practical implications.
Investigating Cloud ERP Adoption in Australian Higher Education Institutions: A Case Study
Authors:   Monash University, Huang Qian , Anwar Misita ,   Monash University, Australia; Swinburne University, Oliver Gillian ,   Monash University, Mahbubur Rahim ,   Sultan Qaboos University
Published: September 2023

Background: Some higher education institutions (HEIs) are constantly under pressure to deliver superior quality education services at low costs through deploying traditional on-premise systems. Cloud-based enterprise resource planning (Cloud ERP) presents an ideal opportunity to lower HEI costs in terms of scalability and pay-per-use features. Adoption of Cloud ERP is, however, still low for the context of HEIs. The successful adoption of Cloud ERP depends not only on the support of system providers but also on understanding Cloud ERP adoption from the client organization perspective. This study explores Cloud ERP adoption in the context of Australian HEIs. Method: This study adopted a case study methodology involving the in-depth semi structured interviews of several key stakeholders. Thematic analysis was used to analyze and interpret interview data. Results: Based on the case study, our findings suggest that this particular Australian HEI was subject to strategic, operational, technological, and financial motives originating from either internal or external locus. Most of the expected motives were realized, except the full flexibility of Cloud ERP. Four major challenges of Cloud ERP implementation were found. Conclusion: This study empirically investigates Cloud ERP adoption in HEIs by identifying the motives, realized benefits and challenges of Cloud ERP adoption, which bridges the research gap of this topic. This study could assist Cloud ERP providers to adjust their marketing strategies to promote the adoption rate of Cloud ERP in HEIs. Understanding the motives, challenges and benefits of IT adoption in HEIs facilitates judicious decision-making prior to selection and minimizes the possibility of the failure of Cloud ERP adoption.