bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Literacy for Students With Intellectual Disabilities
Authors: Holzman Patricia , Thompson Wendy
Published: February 2023

Safe use of media sources is a part of curriculums for all students, including those with intellectual disabilities. Educators are promoting cyber-wellness through social emotional learning (SEL) incorporated with digital and media literacy skills. When students are prepared to face risky online interactions, they are more equipped to safely navigate dangers encountered online. Students with intellectual disabilities may interact safely in virtual settings either for social activities, learning, or employment when prepared with appropriate functional skills and provided accessible methods and tools. Educators utilizing proven instructional strategies can support students with intellectual disabilities as they access the internet. Students' awareness of potential online dangers along with the development of digital literacy skills can motivate them to be positive online risk takers.
Virtual Exchange Experiences Energized by an Educational Technology Paradigm Shift
Authors: Szobonya Patricia , Roche Catherine M.
Published: February 2023

Asynchronous and synchronous modes of online communication utilizing a variety of technology applications provide students with opportunities to engage in both student-to-student and team discourse. Through experiential and project-based learning, students develop skills in digital literacy, virtual teamwork, empathy, and cross-cultural communication—all requisite 21st century skills for employment. The authors will showcase their virtual exchange collaborations utilizing the latest educational tech tools. Challenges, considerations, and opportunities inherent in developing and delivering virtual exchange projects plus student reflections will be shared. Teaching strategies that embrace a diversity, inclusion, equity, and social justice learning environment will be discussed.
Forced Migrations and the Risk of Human Trafficking
Authors: Boskovic Milica , Jankovic Brankica
Published: February 2023

For the last two decades, forced migrations become so massive that no one could deny the fact that millions of people left their homes, maybe forever, running away from wars, civil wars, violence, and/or political victimization. War and violence are for sure two of the most serious traumatic events, as they are long-termed, cause different kinds of injuries, fear, unsafety, and hopelessness – and this is the first stress migrants are faced with. By being concerned for their own or the lives of their families, many migrants agree to be smuggled. But smugglers offer inhumane and often intolerable conditions, placing more migrants in their vehicle or boat than it can receive, and this leads to many migrants' lives being lost. In situations of fear, hopelessness, and uncertainty, which migrants running away from, they are vulnerable to many risks, and one of them is human trafficking, which can occur during their trip, illegal migration, or even when they get the final destination. It is important to understand the difference between smuggling and human trafficking.
The Geopolitics of Conflict-Actuated Mass Displacement in the 21st Century
Authors: Batool Madiha
Published: February 2023

Human migration and displacement are age-old phenomena that no society has ever been able to evade historically. They are experiences that help societies and peoples mature and grow and are developments that make the world demographically and culturally more fertile. On the downside, however, displacements and migrations—when triggered by conflicts—can lead to the spillover of traumatic memories, criminal behaviours, and radical inclinations from one part of the world to another. The 21st century has witnessed multiple internal and external migrations around the globe prompted by conflicts. Are these conflict-induced migrants prone to becoming unofficial emissaries of intractable conflicts and failed states? The study is interested in analysing the geopolitics of conflict-actuated mass displacement in the 21st century. In doing so, it will also excavate how international power struggles affect local populations, lead to both internal and external displacements, and result in almost perpetual conflict cycles.
Outcomes of Conflicts, International Migration Processes, and Their Impact on the State Security and Social Wellbeing
Authors: Chkopoia Sopo , Alaverdov Temuri , Masaberidze Bakari
Published: February 2023

The work deals with the modern international migration processes. It analyzes the main features of forced migration caused by conflicts and their impact on international security. The world faces all types of migration processes including forced, stationery, internal and external, and labor migrations. In this case, the authors highlight that against the backdrop of mass territorial displacement, many states faced demographic problems. Thus, revealing the main causes of international migration processes, its study was of great importance at all stages of the existence of mankind, although today interest in it has especially increased, which is associated with an increase in the scale of migration processes.
State Policy of a Country With Occupied Regions Towards Internally Displaced Persons
Authors: Darchashvili Manana
Published: February 2023

After the end of the Cold War, the issue of expelled citizens due to the violation of human rights and internally displaced persons (IDPs) has become an issue of urgent judgment. At the modern stage, a lot is being done to create such an international system that responds to the needs of IDPs. However, the development of a full-fledged legal framework, institutional arrangements, and strategies to solve difficulties remains an international challenge. Georgia's state bodies, when solving the problems of internally displaced persons (IDPs), act following the Constitution of Georgia, other legislative and subordinate normative acts of Georgia, universally recognized human rights, and norms stipulated by international law. The problem of the displaced population is one of the most important challenges for the country, and active work has been going on to solve it for many years. The steps taken by the state concerning the IDPs are always the subject of public interest because the state has special obligations towards the IDPs.
Georgian Diaspora
Authors: Bakhsoliani Nana
Published: February 2023

Migrations were less typical of sedentary peoples, with private land ownership and farming traditions. The Georgians were one of those. They preserved the territory under the conditions of ancient and almost continuous statehood, and a large part of them still live in their historical homeland. Therefore, the Georgian diaspora in different countries of the world is not very large. The centers of Georgian culture created outside Georgia were perceived as an integral part of the country. Georgian diasporas gathered around them at different times, and through them, they maintained ties with the homeland. The diasporas that escaped violence or were forcibly displaced were more numerous in Fereydan of Persia and the Georgians who emigrated to Constantinople and France due to the conquest by Soviet Russia. The diaspora in France was considered the largest until recently. Mass migration from Georgia in 1992 is an example of those who escaped political danger and economic hardship.
“Connected” Conversations in TESOL Education
Authors: Semingson Peggy Lynn , Kilpatrick Cynthia D. , Kerns William
Published: February 2023

This chapter details strategies for integrating university methods coursework with ESL-focused service learning and focuses on lessons learned from university coursework and service-learning experiences. TESOL educators participated in service learning as part of training in ESL methods, internship, and practicum courses. Service-learning supported content focused on ESL teaching through distance learning. Students were provided with training and resources in the use of technology necessary to take advantage of the opportunities afforded by virtual service learning. Implications address both the importance of maintaining program stability during a time of crisis and responding to broader and short-term trends towards online learning. The authors reflect on the various partnerships that were developed during the pandemic that continue to be of use now that the crisis part of the pandemic has diminished. Broader goals, beyond the pandemic, of preparing TESOL students for preparation to teach in a virtual setting are described.
Streamlining Blended Learning in Higher Education in Kenya
Authors: Dimba Magdalene , King'ori Esther Muthoni , Sawe Emily Cherono , Syallow Maureen
Published: February 2023

Prior to the COVID-19 pandemic, face-to-face learning was the most popular style of teaching in Kenyan universities. However, some institutions offered technology-focused programs with the Open Distance Electronic Learning (ODeL) program being the most popular. ODeL targeted adult learners unable to attend in-person classes. COVID-19 called for the adoption of innovations that would allow resumption of classes in the midst of the lockdowns. The chapter has three objectives: an examination of the history leading up to the regular use of technology in the classroom, a review of the policies and guidelines developed to guide the implementation of blended learning, and a review of the pedagogical skills and learning outcomes of blended learning environments. The authors used qualitative research design to select policy documents that were developed to streamline blended learning in higher education. In addition, an extensive literature review outlined the history of higher education in Kenya and interrogated how the new learning environments have transformed the higher education sector.
Optimization-Based Data Science for an IoT Service Applicable in Smart Cities
Authors: Juneja Vinit , Singh Sonakshi , Jain Vipin , Pandey Kamal Kishor , Dhabliya Dharmesh , Gupta Ankur , Pandey Digvijay
Published: February 2023

There are several research works that are focused on IoT services. IoT services are frequently applicable in smart cities. But there is need to optimize datasets to improve the performance of prediction mechanism during decision making. There have been several studies in area of IoT that have considered role of optimizer for IoT services that are applicable in smart cities. Research work considers PSO technique to get the optimized data set before training operation. The dataset is filtered considering optimization approach. Simulation work is supposed to provide solution in less time with better accuracy.
Applications of Machine Learning in Industrial Reliability Model
Authors: Rath Suneel Kumar , Sahu Madhusmita Kumar , Das Shom Prasad
Published: February 2023

The chapter examines ML methods that appear to be applied in implementing systems with intelligent behaviour. It depends on two workshops on learning in system of intelligent manufacturing, an intensive survey of the literature, and various commitments. Symbolic, sub-symbolic, and hybrid approaches, as well as their applications in manufacturing, are also discussed, as are hybrid solutions that attempt to combine the advantages of several methodologies. The advantages, inadequacies, and impediments of different creation methods are illustrated to decide suitable strategies for explicit circumstances.
Global Cost of Living in Different Geographical Areas Using the Concept of NLP
Authors: Vijarania Meenu , Udbhav Milind , Gupta Swati , Kumar Robin , Agarwal Akshat
Published: February 2023

Cost of living affects the maintenance if a certain standard of living, which includes housing, food, taxes, healthcare, etc. To overcome this issue, the project aims to analyze the amount of money needed to survive in different geographical areas and compare the cost of living in different areas. The analysis of the cheapest and most expensive places in the world is done for proper categorization. For getting proper data there is a need of extracting the latitude and longitude of all different locations. The comparison of expenses in different countries based on different parameters gives an idea about the living standards in different countries. Analyzing different parameters also helps to decide the lifestyle of people in different countries and whether their expenses will be high or low in the particular country. One major type of analysis, which is geospatial analysis, is also used here to study the entities using different topological or geographical properties. The project deals with real-life scenarios people face in day-to-day life when there is a need to decide the lifestyle of living.
The Convergence of Digital Twin, Internet of Things, and Artificial Intelligence
Authors: Yadav Shipra Shivkumar
Published: February 2023

An agricultural digital twin is presented in this research using technologies from the sensing change and smart water management platform projects. Unlike the sensing change project, which created a soil probe, an internet of things is now being developed by the SWAMP project platform for managing water. The authors come to the conclusion that this system is capable of collecting data from the soil probe and displaying it in a dashboard, allowing for the deployment of additional soil probes, as well as other monitoring and controlling devices, to create a fully functional digital twin
RFID MATERIAL Based Electric Vehicle Charging Station
Authors: Santhoshkumar R. , Suresh S. , Sridhar B. , Deepa P. , Balaji P. , Dhinesh B.
Published: February 2023

The variety of EVs on the road aspect is increased; hence the charging stations in necessary in every entire parking buildings and individual provider branch will turn out to be additional dominant. These stations can is accountable for assembly the necessities of the supply grid, EV proprietors, and parking building operators. With an elevated numbs of electrical automobiles (EVs) on the streets, charging communications is gaining an entire extra crucial role in the entire together gathering the desires of the nearby supply grid and of EV users. The emission of the damaging CO2 inside the surroundings from the conventional gas-based vehicles is one of the essential elements for the upward push and fame of electric cars (EVs) within the fresh elegant towns within the current years. In this context, EVs offer better surroundings within the contemporary elegant city. But there exist many demanding situations inclusive of elegant charging, path scheduling, information dissemination etc., for the usage of EVs inside the fresh-day elegant metropolis. So, there's a need for the new strategies and solutions to improve the performance of the existing charging machine of the EVs. Maintaining awareness on these points, this task proposes a new approach for the electrical automobile wireless charging the use of RFID MATERIAL tags together with an optimized path making plans to have a foremost charging value. This proposed gadget RFID MATERIAL system for person identification and charging authorization as part of a elegant charging infrastructure offering rate tracking and manage. The RFID MATERIAL presents a cost-efficient method to perceive and consent to motors for charging and would permit EV charging to is carried out successfully while gazing grid constraints and meeting the needs of EV drivers. After RFID MATERIAL reader initialization, RFID MATERIAL tag study via RFID MATERIAL reader with help of percent microcontroller and RFID MATERIAL tag information are displayed within the liquid crystal display. The automobile charging is based to the entire y on amount/money and robotic the entire y debited from account with assist of RFID MATERIAL and keypad. On this gadget we can monitor our charging degree the usage of IOT module.
On-Line Quality Control in the Injection Molding Machine for the Process Statistic of Thermoplastics Material
Authors: Media Riona Ihsan
Published: February 2023

In this paper, the on-line quality control feature of the injection molding machine based on the statistical process of thermoplastics product has been developed. The optimal process begins with collecting data and setting up the parameter of the injection machine according to the design of experiment. Four control parameters are set up on Demag Ergotech 200-840 Dragon. A series of tests using a body-outdoor led lamp has been conducted by means of both approaches simulation-based and experimental-based by which is injected using two-cavity injection mold. In simulation mode, clamping force and total weight were assigned as final responses, while total weight only is used as a response in experiment mode. The molded-parts were validated using thirty samples that are divided into a three-batch production process. The application of the on-line statistical quality check feature in the injection molding machine can be used as a quality control method by setting up barrel temperature, screw-back position, injection speed, and injection pressure.
Research of Stress Detection Based on Mechanoluminescence
Authors: Wang Ting , Hu Bin , Zhang Yan , Luo Shi Ping , He Xiao Xing
Published: February 2023

Stress and stress concentration are one of the main factors of invalidating load-bearing structural members. Stress detection becomes an important part of industrial production. Mechanoluminescent (ML), which is produced by mechanical stimulation acting on materials, has been suggested to use in stress detection. This work focuses on the development and mechanism of ML, concludes with the applications of ML on the stress measurement, and discusses the specific challenges to the future directions of ML.
Impact Damage Analysis of Skid Landing Gear of the UAV
Authors: Ma Xiao Cheng , Wang Yue , Jia Ya Lan , Dong Jie , Gong Hao
Published: February 2023

In this paper, by analyzing the structure and material characteristics of skid landing gear, the skid landing gear model is established by using CATIA software. In the explicit dynamic analysis type of ANSYS software, the force comparison between the impact surface of soil material and the impact surface of rigid material is made, combined with the change of momentum and energy in the process of touching the ground. This explains the necessity of landing drones on soft landing surfaces such as soil. In addition, LS-DYNA was used to simulate the dynamics of landing gear, and the strength of landing gear was analyzed according to failure criterion.
Metal-Polymer Functional Materials for Hydrogen-Oxygen Fuel Cells with Enhanced Performance
Authors: Lebedeva Marina V. , Antropov Alexey , Erasov Vadim , Golovacheva Vera , Yashtulov Nikolay
Published: February 2023

The most promising direction in alternative energy is hydrogen energy, using hydrogen as a secondary energy carrier. A key component in hydrogen energy is a fuel cell, especially on solid polymer membranes. Increasing the efficiency, reducing the cost and increasing the service life of such elements is the primary task of this direction. These tasks need to be solved from two sides: by improving the parameters of platinum catalysts in electrochemical reactions of energy sources, as well as by improving the qualities of the membrane. The aim of the work is to synthesize and study composites with palladium and platinum nanoparticles in hydrogen-oxygen fuel cells.
Relationship between Different Types of Intelligence and Effect of Music on Intelligence
Authors: Singh Mohita , Sachdev Sunil , Singh Amrita , Raj Dev
Published: February 2023

Background and Aims:

Intelligence is an abstract ability which is easily identifiable and recognizable but interestingly very hard to define. The study of intelligence is a dynamic field which is continuously evolving and expanding. The idea of multiple intelligence includes both interpersonal (to understand other individuals' emotions and intensions) and intrapersonal (to understand one's own emotions) intelligence. The present study was performed to assess the intelligence quotient (IQ), emotional quotient (EQ), social intelligence (SI), and resilience level of subjects and to assess the effect of music on different types of intelligence.

Materials and Methods:

The present study was conducted on 100 college-going students chosen randomly. The study was carried out in two phases. In the first phase, baseline parameters of IQ, EQ, SI, and resilience level were assessed. They were asked to listen to receptive music for 1 month and to maintain the record of the same. In the second phase, the effect of music was studied on parameters.

Results:

Significant correlation was found between IQ, EQ, SI, and resilience scores. Correlation and paired t-test values of each parameter analyzed between baseline and post music intervention levels exhibited significant difference. Comparison of mean values of parameters in males and females studied at baseline level and post music intervention level also exhibited statistical differences at different levels of significance.

Conclusion:

Music improves cognitive abilities in both males and females with more effect on IQ in males and SI in females.
Turmeric as a Local Drug Delivery in Periodontitis
Authors: Mukherji Arnav , Bose Sinthiya
Published: February 2023

Periodontitis is a multifactorial disease. Traditional methods like toothbrushing and manual scaling and root planing are the treatment of choice. However, these methods are time-consuming and not fully effective. To restore periodontal health systemic antibacterials are used as adjuncts, but due to side effect and inability to reach target areas, other alternative methods were devised. Various handicaps of systemic drugs such as side effects, resistance, and growth of opportunistic infection, local drug delivery agents (LDD) in periodontology have gained acceptance and popularity. Haldi/turmeric has been used in our country since time immemorial. It has vast array of therapeutic uses. This review attempts to shed light on the efficacy of curcumin as LDD agent in periodontal infections.
Teenage Pregnancy and its Outcomes in a Tertiary Care Hospital in Assam
Authors: Borah Madhur , Das Bishnu Ram
Published: February 2023

Background:

Teenage pregnancy is one of the determinants of high maternal morbidity and mortality. Assam is known for its highest contribution of maternal death in India. In Assam, around 31% of teenage girls get married before the age of 18, and around 12% teenage girls become mothers before they turn out to be 18 years.

Objectives:

The objective of this study is to know the maternal and fetal outcomes of teenage pregnancy and its determinants in a tertiary care setting in Assam.

Materials and Methods:

A cross-sectional study was conducted among 118 teenage mothers admitted to Jorhat Medical College and Hospital from June to August 2019. Required data on sociodemographic characteristics of the mother, antenatal, intranatal, and postnatal histories, and maternal and fetal outcomes of the pregnancy, were collected in predesigned and pretested schedule. Data analysis was done using Microsoft Excel software. Ethical approval was obtained from the Institutional Ethics Committee.

Results:

Among the 118 teenage mothers which constitute 14.6% of total deliveries conducted during the study period, 61% were anemic during pregnancy and 75.42% of teenagers had term delivery while 19.49% had either preterm or postterm deliveries. Cesarean section was done for 50.85% of pregnancies and 45.77% of teenage mothers had complications such as eclampsia, prolonged labor, cephalopelvic disproportion, and premature rupture of membrane during labor. About 42.73% of the newborns were found to be low birth weight babies. A statistically significant association was found between determinants such as lower socioeconomic class, younger age at marriage, less education of mothers, lack of knowledge about contraceptives, and teenage pregnancy.

Conclusion:

Our study findings indicated a high percentage of teenage pregnancy and increased complications among teenage mothers and newborns.
Prevalence of preoperative anxiety in patients posted for surgical procedures and its relation to the doses of anesthetic drugs: A cross-sectional study
Authors: Omkaram Sindhuja , Reddy C. Gowtham , Murthy P. S. , Chaudhury Suprakash
Published: February 2023

Background:

In patients undergoing surgical procedures, preoperative period is one of the most worrying periods. There are only few studies which revealed that increased preoperative anxiety is associated with increased requirements of doses of anesthetic agents.

Aim:

The aim of this study is to assess the prevalence of preoperative anxiety in patients posted for surgical procedures and its relation to the doses of anesthetic drugs.

Materials and Methods:

This is a cross-sectional, analytical study done between January 2021 and April 2021. A total of 100 patients undergoing surgery have given consent to participate in the study by filling self-designed questionnaire, Amsterdam Preoperative Anxiety and Information Scale (APAIS). Data analysis was done by SPSS version 24 using appropriate statistical tests.

Results:

Preoperative anxiety was noted in 21% of the patients who were undergoing surgery. The association between preoperative anxiety and need for increase in the doses of anesthetic agents during intraoperative period was found to be statistically significant (P < 0.004).

Conclusion:

A significant number of patients required increased amounts of anesthetic drugs to reduce anxiety during intraoperative period. Therefore, appropriate methods have to be introduced to address the concerns of patients undergoing surgery and thereby reducing anxiety.
Positive mental health for all serving the under-served
Authors: Chatterjee Kaushik , Srivastava Kalpana , Prakash Jyoti , Dangi Ankit
Published: February 2023

Mental disorders are major contributors to global burden of disease measured in Disability Adjusted Life Years (7% of all disease burden in 2017). Large treatment gaps for these disorders exist in all parts of the world. In India, overall treatment gap for mental disorders was found to be 83%. Women, children and adolescents, ethnic minorities, LGBTQ+ community, elderly and those living in remote and inaccessible areas have disproportionately higher rates of mental illness. They face unique and characteristic barriers to access to mental healthcare which increases treatment gap. These gaps have persisted despite global efforts and interventions to mitigate these barriers. Hence, there is a need to find alternatives to reduce mental health gap in these groups. Positive Mental Health interventions focuson well-being and health promoting activities, rather than on illness. The potential role of these interventions in promoting mental health and reducing treatment gap has been explored in this article.
Assessment of Perception of Crew on Habitability Factors Onboard Naval Afloat Units Assessment of Perception of Crew Regarding Habitability Factors Onboard Naval Afloat Units
Authors: Sharma Anmol , Batlish Rajesh , Ali Khan Muzzafar
Published: February 2023

Background and Objectives:

Habitability onboard a warship is multifactorial and constitutes the environment in which the crew operates and accommodates while at sea or at harbor. Maritime work environment is a complex man-machine interaction, with human being the dynamic component as the machine is mostly run by set protocols and algorithms. Efficiency of the dynamic aspect of the man machine interaction is driven by multiple correlated and interrelated factors which can be linked to the ambient and external environment in nature. This study was therefore conducted to survey upon the crew serving onboard Indian Naval Ships as to assess crew perception toward various habitability factors onboard.

Materials and Methods:

The descriptive study was carried on board various naval warships. A questionnaire-based analysis was conducted on 384 personnel on active duty.

Results:

Majority of participants agreed that habitability factors have a direct impact on their efficiency while working. Food, ventilation, and adequate living spaces are most crucial with the maximum positive impact on the crew as determined by the survey.

Interpretation and Conclusion:

Subsequent increase in the quality and variety of equipment with an ergonomical approach is the way forward for an efficient and happy crew. A happy and satisfied seafarer on board a ship is the pivot point to determine the efforts in place and the mission in hand.
A Case Report of Synchronous Primary Gastric Hodgkin Lymphoma and Lung Adenocarcinoma and Literature Review
Authors: Kuan Jew Win , Masir Noraidah
Published: February 2023

We report a rare case of a 58-year-old woman who was initially diagnosed as primary gastric (PG) T-cell non-Hodgkin lymphoma, which later was revised as PG Hodgkin lymphoma (HL) with dissemination to the lung (stage IV). The lung lesion was later found to be lung adenocarcinoma (LA) and the diagnosis was revised again as synchronous primary gastric Hodgkin lymphoma (PGHL) and LA which, to our knowledge, was not reported before. This case illustrated the need of vigilance in the diagnosis of lymphoma at uncommon sites and the clinical challenges in managing synchronous malignancies. The rationale of clinical suspicion, the association between PGHL and Epstein–Barr virus, Helicobacter pylori, and other infections, and synchronous PGHL and LA were discussed.
Spontaneous Resolution of Hemophagocytic Lymphohistiocytosis in a Child Infected with Epstein–Barr Virus
Authors: Alfattal Rita , Sadeq Hussain , Ali Abdullah
Published: February 2023

Hemophagocytic lymphohistiocytosis (HLH) is a rare and complex disorder that involves numerous hematological and immunological reactions. These reactions, if left untreated, may lead to multiorgan failure and death. Corticosteroids are the mainstay of HLH therapy which may also comprise other chemotherapeutic or immunotherapy agents. The components of the 2004 HLH diagnostic criteria may intersect with several other conditions. In this report, we present the case of a 4-year-old boy who was diagnosed with Epstein–Barr virus-related infectious mononucleosis complicated by clinical and laboratory features consistent with HLH, which self-resolved completely without HLH-directed therapy.
Outcome of Haploidentical Hematopoietic Stem Cell Transplantation with a Donor and Recipient Infected with SARS-CoV-2 Infection
Authors: Ali Gad Allah , Altareb Majed , Chaudhri Naeem , Alfraih Feras Abdulaziz
Published: February 2023

The current coronavirus disease 2019 (COVID 19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV 2), has impacted many facets of hematopoietic cell transplantation (HCT) in both developed and developing countries. The full impact of the COVID 19 pandemic, caused by the SARS CoV 2, on the field of hematopoietic cell transplantation (HCT) is unknown. Here, we report a rare case of a 21-year-old male patient known to have chronic myeloid leukemia (CML) with progression to T-cell lymphoblastic lymphoma as extramedullary blast crisis of CML. The patient was treated by pediatric chemotherapy regimen then. He underwent haploidentical stem cell transplantation. Posttransplantation, on day +7, he developed SARS-CoV-2 after receiving stem cell graft from a donor who was diagnosed with SARS-CoV-2 on the day of stem cells harvesting. The case elaborates complications and outcome of a patient receiving stem cell transplant from a donor with SARS-CoV-2 infection.
Correlation of Erythroferrone and Hepcidin Hormones with Iron Status Levels in Patients with Iron Deficiency
Authors: Talawy Tiba Sabah , Bylappa Sunil Kumar , Ismail Marwan , Kandakurti Praveen Kumar , Gopakumar Aji , Babker Asaad Ma
Published: February 2023

INTRODUCTION:

Iron-deficiency anemia (IDA) can be grouped under low hepcidin and high erythroferrone (ERFE) anemia. There is a negative correlation between ERFE and hepcidin, irrespective of the type of anemia. ERFE is a mediator of the response to erythropoietic stress, suppressing hepcidin to promote the mobilization of stored iron and the absorption of dietary iron.

OBJECTIVE:

The objective was to determine the effect of ERFE hormone on hepcidin level as iron metabolism regulator in patients with iron deficiency (ID).

METHODS:

The study included 50 female patients with ID who were investigated for complete blood count, serum levels of ferritin, and serum levels of iron using automated hematology, immunology, and chemistry analyzer. ERFE and hepcidin were measured by a specific enzyme-linked immunosorbent assay kit.

RESULTS:

The serum ERFE levels were higher than normal in all cases and were negatively correlated with serum hepcidin (r = −0.023). In IDA, serum ERFE concentration had a nonsignificant negative correlation with hemoglobin (Hb) concentration. Serum hepcidin concentration had a nonsignificant negative correlation with Hb concentration. Serum ERFE had a nonsignificant negative correlation with Hb% in severe IDA (r = −0.679; P = 0.094) and mild IDA (r = −0.068; P = 0.789). ERFE had a nonsignificant positive correlation with Hb% in moderate IDA (r = 0.069; P = 0.793). Serum hepcidin had a nonsignificant positive correlation with Hb% in severe IDA (r = 0.036; P = 0.939). Serum hepcidin had a nonsignificant negative correlation with Hb% in mild IDA (r = −0.079; P = 0.764) and moderate IDA (r = −0.179; P = 0.491).

CONCLUSIONS:

The potential of ERFE and hepcidin in diagnosing and categorizing ID disorders is promising. Understanding the mechanism of ERFE/hepcidin interaction will help in developing ERFE-/hepcidin-targeted therapies.
Fetal Hemoglobin Inducer Activity of Moringa oleifera, Curcuma aueruginosa Roxb., and Artocarpus altilis Based on the Gamma Globin Expression
Authors: Amanda Nisa Widya , Nainggolan Ita Margaretha , Batubara Irmanida , Saepuloh Uus , Darusman Huda Shalahudin
Published: February 2023

BACKGROUND:

Beta (β)-thalassemia is a common single-gene blood disorder resulting in a decrease or absence of β-globin chain synthesis. In β-thalassemia major, an imbalance of α/β globin chains results in severe oxidative stress that leads to pathological conditions. Reactivating the gamma (γ)-globin gene will overcome the excess alpha (α)-globin chains and relieve β-thalassemia patients' clinical course.

AIMS AND OBJECTIVES:

This study aimed to determine the most competent herbal extract with high efficiency in inducing γ-globin gene expression to facilitate β-thalassemia patients.

MATERIALS AND METHODS:

This study used K562 cell line culture to assess the fetal hemoglobin (HbF) induction efficacy of Moringa oleifera (MO), Curcuma
aueruginosa Roxb. (CA), and Artocarpus altilis (AA). We carried out the benzidine test to count hemoglobin-containing cells and RT-qPCR to measure γ-globin gene expression.

RESULTS:

The benzidine test showed that MO extract was the highest value (3%) in inducing fetal hemoglobin. However, based on RT-PCR analysis, CA extract had the most significant (2.39 fold change) ability to reactivate the γ-globin gene compared to Hydroxyurea as a positive control.

CONCLUSION:

The different properties and levels of MO and CA testing in antioxidant and reactivation of gene expression mechanism most probably influenced the discrepancy between the benzidine test and RT-qPCR results.
Role of Compression Sonoelastography in Aiding Differentiation of Benign and Malignant Solid Hepatic Lesions
Authors: Bala Archana , Kadavigere Rajagopal , Prakashini K. , Narayanan Ramakrishna
Published: February 2023

Background:

The liver is primarily or secondarily involved by numerous vascular, metabolic, infectious, and neoplastic processes resulting in formation of focal liver masses, and the detection of such focal liver lesions is frequently accomplished with sonography. However, the categorization a liver mass as benign or malignant on ultrasound has always been a diagnostic dilemma.

Objective:

This study aimed to assess if the addition of compression sonoelastography to conventional B-mode ultrasound aided in diagnostic accuracy of the focal hepatic lesions.

Materials and Methods:

We evaluated B-mode characteristics of 52 liver lesions followed by calculation of their strain values on compression sonoelastography. The lesions were categorized as benign or malignant by ascertaining a cutoff strain value and the comparison was made with the histopathological diagnosis/contrast-enhanced computed tomography characteristics of the lesions.

Results:

The mean strain index value of malignant hepatic lesions (2.12 ± 1.06) was statistically higher than the benign lesions (0.92 ± 1.06) with 2-tailed P = 0.002. The sensitivity, specificity, and positive and negative predictive values of compression sonoelastography in diagnosing a malignant pathology were 74.4%, 88.9%, 94.6%, and 46.7%, respectively, and the additional evaluation of B-mode features yielded higher sensitivity (95.4% vs. 83.7%) and negative predictive value (75% vs. 46.7%).

Conclusion:

Compression sonoelastography is an efficient and beneficial complementary tool to B-mode imaging in evaluating solid liver lesions.
Hysteroscopic evaluation of chronic endometritis and its relation to unexplained infertility
Authors: Hamouda Eman Fawzy Abdelazeez , Farahat Manal Abd El-Raoof , Dawood Abd Elghaffar Saeed , Shaheen Karam Abd EL-Fatah
Published: February 2023

Background

Hysteroscopy is considered the gold standard for detecting diseases of the uterine cavity. It is simple, safe, and can be performed in an outpatient clinic. Although endometritis is not clinically clear, it may lead to infertility. Moreover, there is strong evidence that endometritis may lead to a premature spontaneous birth.

Aim

This study aimed to assess the diagnostic value of diagnostic hysteroscopy in patients with chronic endometritis.

Patients and method

The current study was performed on 50 women with unexplained infertility. All patients presented to the outpatient clinic of Tanta University Maternity Hospital in the follicular phase of menstruation.

Results

Hysteroscopic findings in the form of hyperemia, edema, micropolyps, and dark blue spot suggesting chronic endometritis were found in 31 cases. Histopathological examination confirms the diagnosis of chronic endometritis in 28 cases by detection of plasma cells in the endometrial biopsy. Microbiological examination showed a positive growth in 17 cases by detection of organisms in the endometrial biopsy; 1 of them showed positive chlamydial infection and 4 cases of mycoplasma in the multiplex polymerase chain reaction test. There was a significant association between hysteroscopic picture suggesting chronic endometritis and its confirmation by histopathological examination of endometrial biopsy.

Conclusion

Hysteroscopy is a convenient examination for detecting chronic endometritis. It could be applicable for investigating asymptomatic infertile patients. Antibacterial, antichlamydial, and antimycoplasma drugs have a good result in chronic endometritis. Endometrial dyeing with methylene blue at hysteroscopy improves the detection of chronic endometritis. More studies are recommended for endometrial evaluation by hysteroscopy.
MRI with diffusion-weighted image in assessment of hepatic fibrosis and steatosis
Authors: Ali Elkholy Nahla K. , Ramadan Kareem M. , Ziada Dina H. , Hefeda Mohamed M.
Published: February 2023

Background

FibroScan and diffusion MRI have been recommended for staging and noninvasive diagnosis of hepatic fibrosis and steatosis.

Aim

To evaluate the diagnostic efficiency of conventional MRI and diffusion-weighted imaging in diagnosis and staging of hepatic fibrosis and steatosis.

Patients and methods

This research was conducted on 30 patients proven to have hepatic fibrosis or steatosis based on clinical, laboratory, and/or ultrasonographic criteria. Both sexes were included. Their age ranged from 20 to 60 years. The participants were sent to the MRI Unit in the Department of Radiodiagnosis, Tanta University Hospitals, over a period of 12 months from March 2021 till March 2022.

Results

There was a significant difference between apparent diffusion coefficient values of F0 and F1, F3, and F4 (P=0.010, 0.041, and 0.019, respectively); however, no significant difference was observed among the other various fibrosis stages.

Conclusions

FibroScan is a good noninvasive route for detection of hepatic fibrosis and steatosis. It can differentiate among various phases of hepatic fibrosis and steatosis. MRI can differentiate between fibrotic and nonfibrotic liver and also steatotic from nonsteatotic liver. However, it cannot differentiate between various phases of hepatic fibrosis and steatosis, especially the intermediate stages.
The role of transpaterllar viewing portal in anterior cruciate ligament reconstruction
Authors: Mohamed Ali N. , Elfors Elsyed M. , Megahed Abd E. Abd Elhafez , Saeid Mhamed S.
Published: February 2023

Background

Anatomical anterior cruciate ligament (ACL) reconstruction aims to place the ACL graft within its anatomical orientation. Malposition of the graft especially on the femoral side is the persisting complication of ACL reconstruction. The lateral femoral condyle can be visualized by the transpatellar viewing portal to place the graft in a more anatomical position.

Aim

To evaluate the result of arthroscopic ACL reconstruction using transpatellar portal viewing.

Patients and methods

This study included 31 patients in whom the torn ACL will be reconstructed arthroscopically using the transpatellar portal viewing and AAMP at Tanta University Hospital with a period of 6 months of follow-up.

Results

Transpatellar portal technique has been used to create the femoral tunnel independently to the tibial tunnel for more anatomic position that lead to improvement in rotational stability, without increased complexity. The central portal offers the advantage of more anatomical ACL reconstruction with improved femoral footprint placement. Transpatellar portal provides an excellent visualization of the femoral footprint and therefore reduces the incidence of improper tunnel positioning during ACL reconstruction without significant complications.

Conclusion

Anatomical insertion of the hamstring graft using the transpatellar portal viewing can offer an excellent restore of the anterior knee stability.
Four-dimensional ultrasound in the diagnosis of intrauterine central nervous system anomalies: four dimensional in CNS congenital anomalies
Authors: Ahmed Abd-Allah Eman A. Abd El-Hakeem , Hassanien Omar A. , El-Aziz Al Darf Ayman A. , Al Ashwah Mohammad Al Huseni
Published: February 2023

Background

Central nervous system (CNS) anomalies are an important factor of neonatal deaths. Three-dimensional (3D)/4D ultrasound (US) has an advantage over the conventional 2D US as it provides additional multiple options like multiplanar view, tomographic view, and surface rendering view leading to accurate diagnosis of fetal congenital anomalies.

Aim

The aim of this study was to evaluate the role of the 4D US in the diagnosis of in utero congenital CNS anomalies.

Patients and methods

The current study was conducted on 30 pregnant women with suspected congenital CNS anomalies by 2D US in Tanta University Hospitals. All the patients were subjected to 2D and 4D US examination in cases with suspected anomalies by 2D US.

Results

Out of 30 anomalies, two (6.5%) anomalies were lobar holoprosencephaly; six (20%) anomalies were anencephaly, three (10%) anomalies were exencephaly, one (3.5%) anomaly was aqueductal stenosis, three (10%) anomalies were chiari malformation with its two types I and II, and three (10%) anomalies were Dandy–Walker. Three anomalies were hydranencephaly (10%), three (10%) meningocele, one (3.5%) spina bifida, and two cases were obstructive hydrocephalus distal to the 4th ventricle (obstruction of foramen of luschka and magendie) (6.5%). As regards brain anomalies, sensitivity of 4D US=96.4%, specificity of 4D US=100%, positive predictive value=100%, negative predictive value=50.0%, and accuracy=96%. So, 4D US is more superior to 2D US in demonstrating anomalies of the CNS (through multiplanar view and tomographic views), which may affect the postnatal outcome. 4D US offers precise demonstration of normal and abnormal fetal structures through its different modes, so it helps in accurate prenatal diagnosis of CNS anomalies.

Conclusion

4D US is considered now an important diagnostic tool in fetal medicine as it provides many advanced diagnostic options such as multiplanar view or tomographic imaging, volume calculation, and surface rendering mode, which aided in early diagnosis of fetal anomalies and improved postnatal outcome.
Root Cause Analysis of Drive Noise in an Agriculture Machine End
Unit
Authors: Chaudhari Dipesh Ashok , Dasabai Balavardhan Reddy , Bogue Bradley , Faulkner Scott E.
Published: February 2023

In any off-highway machinery throughout the product development cycle, noise is
considered an important characteristic. This characteristic drives the product
quality, safety, and productivity and meets the homologation requirements.
Identifying the critical noise source and finding out the true root cause of the
noise source is a very critical element in improving the design to reduce the
noise levels. A systematic approach is needed to understand the behavior of the
system, which can be achieved through collaborative efforts among the analysis,
design, and testing teams.

This paper describes how virtual analysis helps to determine the main source of
noise radiation in the audible frequency range of the human ear. The sound
pressure level (SPL) in the test data at the end unit drive of an agriculture
machine showed high peaks at a few frequencies in the critical frequency range.
The spectral content remains the same regardless of the backshaft speed. The
noise goes away when the tensioner sprocket center nut is loosened. In the
initial stage, the accuracy of the end unit drive finite element (FE) model is
ensured by comparing the virtual driving point impedances with test data for
both loose and tight nut conditions. In the later stage, the acoustic finite
element method adaptive order (FEM AO) model is developed [1] and correlated with test data of SPLs. In the final
stage, panel contribution analysis is carried out to determine the critical
noise-radiating component. This validated model will be confidently used to
improve the design further.
Tehran Museum of Contemporary Art (TMoCA)
Authors: Cubbon Alexandra
Published: February 2023

The Tehran Museum of Contemporary Art (TMoCA) is an art museum located next to Laleh Park, in Tehran, Iran. The museum houses a large collection of modern and contemporary Iranian art, as well as one of the most valued collections of modern Western art outside Europe and North America, mostly dating from the late nineteenth to the mid-twentieth century. In 1977, having purchased large quantities of art during Iran’s 1970s oil boom, the European-educated Iranian Empress Farah Pahlavi inaugurated TMoCA. The Iranian architect Kamran Diba designed the museum, incorporating elements of traditional Persian architecture into a structure that many consider to be a piece of contemporary art itself. The inauguration of TMoCA prior to the 1979 Iranian Revolution exemplified Mohammad Reza Pahlavi’s secular monarchy and symbolised a common bond between Iran and the West.