bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-Term Effects of Treatment Modalities on Metabolic Health, Fertility Outcomes, and Cardiovascular Risks in Lean Women with Polycystic Ovary Syndrome (PCOS): A Systematic Review
Authors: Mendpara Vaidehi , Ganampet Narendranath Reddy , Afroze Sabah , Gnanasekaran Sulochana , Sahu Sweta , Atikah Rahmatulhusna , Rajpal Shreyaa , Raghavan Prithvi , Ajith Krithika , Parmar Mihirkumar P. , Venugopal Vishal
Published: September 2023

Oligomenorrhea with different degrees of follicular and adrenal hyperandrogenism are the hallmarks of the condition of polycystic ovary syndrome (PCOS). For some of the women in their reproductive years, this endocrine illness is incredibly prevalent and comprises a variety of disorders. There are a set of symptoms, such as hirsutism, acne, and insulin resistance, for identifying the characteristics of PCOS. Various treatment modalities have been opted for over the years for the treatment and management of this condition, among which metformin and flutamide are the most prevalent, along with lifestyle modifications as prevalent recommendations to patients. Weight management for obese patients is the most challenging aspect of PCOS management. Still, similar findings are found in women with lean physiology or a normal BMI, indicating that PCOS symptoms prevail and occur irrespective of the BMI, but obese or overweight women face more problems. We determined the long-term effects of treatment modalities on PCOS symptoms and their improvement. Metformin was reported to primarily increase the blood levels of glucose as well as BMI. Blood pressure was also maintained among various researchers, and DHEAS levels were also altered along with serum sex hormone-binding globulin in the plasma of patients undergoing treatments specific for PCOS patients with a normal BMI or lean PCOS. Further studies with more extensive parameters being employed need to be conducted for the determination of the exact mechanism and cause of the disease to ease the treatment process.
Robotic Hartmann’s reversal – feasibility and technical aspects
Authors: Barone Mirko , Ippoliti Massimo , Masetti Michele , Mucilli Felice
Published: September 2023

Hartmann’s reversal as a staged procedure after emergency surgery is a major abdominal operation with undeniable skill-demanding steps. The robotic approach and its advantages seem to be a safe and feasible technique and could overcome necessary technical compromises of laparoscopy, ensuring a significant reduction in restoration failures or conversion.
Parameter estimation for stable distributions and their mixture
Authors: Hajjaji Omar , Manou-Abi Solym , Slaoui Yousri
Published: September 2023

In this paper, we consider parameter estimation of univariate α-stable distributions and their mixture. We propose firstly an estimation method based on the characteristic function by the use of a Gaussian kernel estimator of the density distribution. The choice of the optimal bandwidth parameter was done using a plug-in method. We highlight another estimation procedure for the maximum likelihood framework based on the false-position algorithm to find a numerical root of the log-likelihood through the score functions. In the case of a mixture α-stable distributions, the EM algorithm and the Bayesian estimation method were modified in order to propose an efficient tool for parameter estimation. Although we have limited the mixture study to two components, the proposed methods can be generalized to several components of mixture. A simulation study is conducted to evaluate the performance of our methods which are then applied to real data. Our results seems accurately estimating mixture of α-stable distributions. The application concerned the estimation of reproduction number of the Covid-19 in Mayotte and the Enzyme dataset density distribution. We compare the proposed methods along with a detailed discussion, and we conclude with some other forthcoming works.
Aseveljien tulkit. Jatkosodan monikielinen arki
Authors: Kujamäki Pekka
Published: September 2023

Interpreting brothers-in-war. Multilingual day-to-day life during the Continuation War in Finland This volume looks at the Finnish-German military alliance (1941–1944) as a translation zone – a multilingual network of military, administrative and civilian encounters that was held together by linguistically versed soldiers and civilians acting as interpreters and translators. It focuses on interpreters and liaison officers of the Finnish Liaison Staff in Rovaniemi, who were assigned to the staffs of the German army units with the task of maintaining communication between the two armies and assisting German troops in their daily matters. Furthermore, attention is paid to Finnish civilians, especially women whose language skills made them candidates for a range of mediation tasks in the German units. The reconstruction of military interpreters’ and liaison officers’ tasks and mediation agency between the two military cultures is based on their war-time weekly reports, whereas the civilian interpreters’ experiences are drawn from a variety of autobiographical accounts, including interviews.
MICROALGAS: UMA ESTRATÉGIA SUSTENTÁVEL NA TRANSFORMAÇÃO E OBTENÇÃO DE COMPOSTOS ORGÂNICOS
Authors: Victor Mauricio , Moutinho Fernando , Riatto Valéria
Published: September 2023

MICROALGAE: A SUSTAINABLE STRATEGY IN THE TRANSFORMATION AND OBTAINING OF ORGANIC COMPOUNDS. The present review presents the biotechnological potential of microalgae, highlighting its applications in biofuels, bioremediation, production of bioactive compounds, biocatalysts, and biofertilizers. Microalgae are photosynthetic microorganisms that combine characteristics of plants and heterotrophic microorganisms, such as yeasts, bacteria, and fungi. They can be considered biotechnological agents of extreme versatility and metabolic adaptability. Its photosynthetic efficiency can absorb large volumes of anthropogenic CO2 and convert it into biomass rich in compounds of high biological and energetic value, enabling the development of sustainable bioremediation processes and the production of third-generation biofuels and biofertilizers. In addition, its biomass has aroused interest in obtaining compounds with biological action, such as carotenoids, mycosporine-like amino acids, polyunsaturated fatty acids, sterols, phycocolloids, carbohydrates, and proteins. The biotechnological potential of microalgae does not end with the production and extraction of its biomass. Its dynamic and adaptive metabolism allows its use in the biotransformation of xenobiotic substrates and the production of compounds of chemical and pharmaceutical interest. In this perspective, microalgae have application qualities as a biotechnological platform in developing synergistic processes between the environment, society, and industry, thus contributing to the expansion and use of Green Chemistry and strengthening the circular economy.
Use of information and communication technologies to promote the learning process of students with intellectual disabilities
Authors: Vera-Mera María Gema , Pinda-Román Nathaly Jessenia , Loayza-Solórzano Michelle Stefany , Ordoñez-Calva Alexandra Fernanda , Olmedo-Zambrano Verónica Ximena
Published: September 2023

Students with intellectual disabilities have difficulties in advancing in the teaching-learning process, because traditional methods are used by teachers, and this causes poor performance. The objective is to introduce the use of computer and communication technologies to improve academic capabilities, the methodology used was descriptive, qualitative, and bibliographic review. The results obtained indicate that the use of new technologies enhanced the abilities of the students, confirming cognitive improvements for learning the subjects, in this way it was proven that these tools allow greater development of the academic skills of each of them.
existence of lexicon Taru Pramana on Balinese traditional medicine
Authors: Claria Dewa Ayu Kadek , Artawa Ketut , Satyawati Made Sri , Putra Anak Agung Putu
Published: September 2023

This paper explains the existence of lexicon Taru Pramana on Balinese traditional medicine by using ecolinguistic perspective. Taru Pramana known as medicinal plants or herbal medicine in Bali where their existence is need to be preserved as one of the cultural heritages that reflects the local wisdom. The ecolinguistic perspective help this research concern in documenting the lexicon by listing the lexicon and their benefits or functions to avoid the extinction of the use of lexicon itself. The results show that the lexicon of medicinal plants in the concept of Taru Pramana has experienced a shift in the term of their naming and functions referring to the habits of the community in modern times which caused the medical plants no longer used in traditional ways as loloh (to drink) or boreh (to rub) but through several chemical processes.
Diversity of Ant Species (Hymenoptera: Formiciidae) in Flower Plants Combination on Ratoon Sugarcane
Authors: Mawaddah Rabbiana , Rahardjo Bambang Tri , Mudjiono Gatot
Published: September 2023

This research aims to examine the effects of several refugia plant treatments on the diversity and number of ants in the ratoon sugarcane system. The diversity and abundance of ants in the plantation's surrounding habitats can fluctuate. Three combinations of flowering plants were used in the study: Turnera subulata Sm (Malpighiales: Passifloraceae), Cosmos sulphureus (Asteraceae: Asteraceae), and Zinnia elegans Jaqc (Asterales: Asteraceae). Ant samples were collected using yellow sticky traps and traps and yellow pan traps. R. software was used to examine all of the data. 4 subfamilies, 14 genera, and 25 species: Diacamma sp., Technomyrmex sp., Camponotus sp.1., Iridiomyrmex sp., Delichoderus sp., Leptogenys sp.; Odontomachus sp., Polyrachis sp., Pheidole sp., Tetramorium sp., Monomorium sp., Crematogaster sp., Oecophylla smaragdina was identified from the report's results, this included 1-86 individuals. Tetramorium sp. and Odonthomachus sp. were the most common ants found at the study site. Even before compared to the other treatments, the combination of refugia and Z. elegans, C. sulphureus, T. subulata treatment used to have a significant impact on the presence of ants, increasing the population by 21%. This study discovered that combining refugia could increase ant diversity in ratoon sugarcane. The diversity index value for all treatments was almost the same, in the range of 2.-9-2.82, indicating that the main composition of refugia was moderately diverse.
Señal acústica de Obolopteryx eurycerca Barrientos-Lozano y Rocha-Sánchez (Orthoptera: Tettigoniidae: Phaneropterinae)
Authors: Salinas-Dosal Hillary G. , Barrientos-Lozano Ludivina , Rocha-Sánchez Aurora Y. , Almaguer-Sierra Pedro , González-Gaona Othón J.
Published: September 2023

En Ensifera (Tettigoniidae: Phaneropterinae), los machos producen señales acústicas mediante estridulación tegminal; estas señales funcionan en primera instancia para atraer hembras conespecíficas sexualmente receptivas. El estudio de la bioacústica es, además, una herramienta complementaria en estudios morfológicos tradicionales, ya que estas señales son especie-específicas y permiten diferenciar especies morfológicamente similares (crípticas). Las señales acústicas representan un sistema importante de comunicación intra e interespecífico. Los miembros de la familia Tettigoniidae se destacan por la producción de señales acústicas que frecuentemente son inaudibles al oído humano [frecuencia (f) > de 20 kHz]. México posee una amplia diversidad de insectos, sin embargo, pocos estudios se han enfocado al conocimiento del repertorio acústico de éstos. En este trabajo se describe por primera vez el canto ultrasónico de llamado de Obolopteryx eurycerca Barrientos-Lozano & Rocha-Sánchez, 2016. Ejemplares en estudio se recolectaron en el municipio de Hidalgo, Tamaulipas, México. La señal acústica de llamado de los machos consiste en la producción de equemas de tres sílabas, que se emiten en forma continua por periodos largos de tiempo (± 1h). Se compara la señal acústica de O. eurycerca con la de O. castanea (Rehn & Hebard, 1914) y se discuten las ventajas de la comunicación acústica ultrasónica en Ensifera.
Geostatistical assessment of unconfined compressive strength of rocks in Northeast Jeddah, Saudi Arabia
Authors: Alghamdi Mohammed A. M.
Published: September 2023

The determination of rock strength holds paramount importance in the field of engineering geology. In this study, we conduct a comprehensive geostatistical evaluation of the unconfined compressive strength (UCS) within a 100 km2 area situated in northeast Jeddah, Saudi Arabia. The UCS values were indirectly estimated using an empirical equation based on the Schmidt hammer rebound method, resulting in a range of strengths from 9.2 to 198.4 MPa. The corresponding mean UCS values vary between 60.3 to 81.7 MPa, with standard deviations ranging from 18.6 to 45.3 MPa. The analysis revealed that, among the sites examined, a specific location exhibited the highest median UCS value of 72.2 MPa, while another site recorded the lowest value of 56.2 MPa. Based on the distribution of UCS values, the study area was classified into five distinct strength categories: very low, low, medium, high, and very high. Notably, the majority of variability in UCS values was confined within the middle 50% range, as evident from the interquartile range (IQR) below 30 MPa. Additionally, certain sites displayed a tighter cluster of UCS values, while an IQR of DEFJ≥60 indicated a more widespread distribution of strength values. Furthermore, two locations were identified as representing the minimum and maximum UCS values within a 95% confidence interval. The UCS in location A was estimated at 60.25±9.14 MPa, whereas in location B, it was 81.72±8.50 MPa. These findings offer valuable insights into the rock strength characteristics of the designated area, providing essential data for engineering and geotechnical applications.
Improvements to the CPI index series for residential telecommunications services
Authors: Akin Bradley , Bieler John , Brown Craig , Chicarella Kerri
Published: September 2023

Residential telecommunications services consist of a combination of telephone, internet, and television services. In February 2019, the U.S. Bureau of Labor Statistics (BLS) began to adjust the price quotes of residential telecommunications services to improve the accuracy of Consumer Price Index series. However, BLS analysts experienced a few challenges. This article identifies and addresses those challenges.
Mapping Respiratory Health Digital Interventions in South and Southeast Asia: Protocol for a Scoping Review
Authors: Evans Laura , Evans Jay , Fletcher Monica , Abdullah Adina , Ahmed Zakiuddin
Published: September 2023

Background

The last 2 decades have been a time of exponential growth and maturation for digital health, while the global burden of respiratory disease continues to grow worldwide. Leveraging digital health interventions (DHIs) to manage and mitigate respiratory disease and its adverse health effects presents itself as an obvious path forward.

Objective

We aimed to understand the current digital landscape and enabling environment around respiratory health to reduce costs, avoid duplication, and understand the comprehensiveness of DHIs.

Methods

This study will follow a scoping review methodology as outlined by Arksey and O’Malley, the Joanna Briggs Institute, and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. MEDLINE, Embase, CINAHL, PsycINFO, Cochrane Library, Web of Science, PakiMedNet, and MyMedR databases will be searched along with key websites, repositories, and gray literature databases. The terms “respiratory health,” “digital health,” “South Asia,” and “Southeast Asia,” as well as related terms will be searched. The results will be screened for duplicates and then against the inclusion and exclusion criteria. For the studies included, data will be extracted, collated, and analyzed.

Results

The scoping review was started in July 2023 and will be finalized by February 2024. Results will be presented following the World Health Organization’s classification of DHIs to categorize interventions in a standardized format and the mobile health evidence reporting and assessment checklist to report on the effectiveness of interventions. Further exposition of the evidence extracted will be presented through narrative synthesis.

Conclusions

As DHIs continue to proliferate, the need to understand the current landscape becomes more pertinent. In this scoping review, we will seek to more clearly understand what digital health tools and technologies are being used in the current landscape of digital health in South and Southeast Asia for respiratory health and to what extent they are addressing the respiratory health needs of the region. The results will inform recommendations on digital health tools for respiratory health in South and Southeast Asia will help funders and implementers of DHIs leverage existing technologies and accelerate innovations that address documented gaps in the studied countries.

International Registered Report Identifier (IRRID)

DERR1-10.2196/52517
Barriers to Postdischarge Smartphone App Use Among Patients With Traumatic Rib Fractures (Preprint)
Authors: Berrigan Margaret T , Beaulieu-Jones Brendin R , Baines Rachel , Berkowitz Seth , Evans Heather , Brat Gabriel A
Published: September 2023

UNSTRUCTURED

Rib fractures commonly result from traumatic injury and often require hospitalization for pain control and supportive pulmonary care. Although the use of mobile health technology to share patient-generated health data has increased, it remains limited in patients with traumatic injuries. We sought to assess the feasibility of mobile health tracking in patients with rib fractures by using a smartphone app to monitor postdischarge recovery. We encountered patient, institutional, and process-related obstacles that limited app use. The success of future work requires the acknowledgment of these limitations and the use of an implementation science framework to effectively integrate technological tools for personalized trauma care.
MANUBRIAL INDEX–A RELIABLE GUIDE IN DETERMINING THE SEX OF THE STERNUM
Authors: MAKHIJA KALPANA , MEHRA SANDHYA , JAIN AARUSHI , SHARMA JAG MOHAN
Published: September 2023

Objective: Sexing an unknown skeleton is a very important and difficult process that anatomists and jurists have to fulfill. Sex can be predicted by the sternum with 90% accuracy. It is crucial to predicting age in the middle age range and sternum is particularly useful for it. In the study conducted for sexing the sternum, different measurements were compared and it was found that manubrium alone is a good tool for gender differentiation of the sternum.
Methods: Study was conducted on 100 Sternums of known age and sex which were collected from the postmortem room of the forensic department after taking due consent from the attendants of the deceased. Different measurements of manubrium were taken and contrasted for gender differentiation. ANOVA was used to evaluate the statistical significance.
Results: It was found that among morphometric criteria of prosternum manubrial index was found to be accurate and reliable along with clear-cut demarcation in length and width of the manubrium sterni of two sex.
Conclusion: It was concluded by this study that the manubrial index is a trustworthy tool for sexing sternum and manubrial width could be fairly reliable criterion for determining sex of the sternum.
PREVALENCE OF ASYMPTOMATIC URINARY TRACT INFECTION IN PREGNANT AND NONPREGNANT WOMEN IN A TERTIARY CARE TEACHING HOSPITAL
Authors: LAXMI RAJAMANICKAM VENKATA , PIDUGU SAILAJA , SREE ALLAVARAPU RAMYA
Published: September 2023

Objective: The study's main objective was to isolate and characterize the bacteria that cause asymptomatic UTIs in pregnant and nonpregnant women attending a tertiary care teaching hospital.
Methods: It is a comparative cross-sectional study that was carried out from January 2021 to January 2022. A structured questionnaire was used to gather clinical information (such as parity and the history of UTIs) and sociodemographic data (such as age, marital status, educational level, place of residence, occupation, and income) from eligible participants. A total of 200 urine samples were collected (100 pregnant and 100 nonpregnant) and analyzed using standard microbiological methods for the detection of isolates and their antibiotic sensitivity using the Kirby-Bauer method.
Results: Most patients who participated were aged 21-30 y (50.5%). E. coli incidence was more in UTI of pregnant women (42.3%) and nonpregnant women (34.2%). Among the 33 isolates of E. coli from pregnant and nonpregnant women, most strains were resistant to amoxicillin+clavulanic acid (57.6%) and cotrimoxazole (54.5%). They were sensitive to other tested antibiotics like norfloxacin, nitrofurantoin, gentamicin, and cefuroxime.
Conclusion: Pregnant women were more likely to get UTIs than nonpregnant women, and the frequency of UTIs among women was more significant. It is recommended that women, especially pregnant women, undergo routine UTI screenings to identify infected cases and receive prompt treatment to prevent urinary problems.
“BACTERIOPHAGE THERAPY” AN EMERGING CURE FOR BACTERIAL DISEASE
Authors: GUPTA TEJASV , KANCHAN  , BHAGYAWANT SAMEER S.
Published: September 2023

Bacteriophages are viruses that infect bacterial cells and have been explored for their potential in treating bacterial infections. This review discusses the taxonomy of bacteriophages and the safety concerns in phage therapy. Although bacteriophages were initially considered safe for humans and animals, recent research indicates potential interactions with eukaryotic cells, raising questions about safety. Nevertheless, successful phage therapy cases have been reported, showing promising results in treating biofilm-based and multidrug-resistant infections. The use of bacteriophages has demonstrated minimal side effects and appears to be a viable alternative to traditional antibiotics. However, more research and controlled clinical trials are needed to fully understand the efficacy and safety of phage therapy in various clinical settings.
STUDY OF DETERMINANTS OF PERSISTENT POSTPARTUM HYPERTENSION AT 6 W IN WOMEN WITH PRE-ECLAMPSIA
Authors: CHANDRA VAISHALI , AGGARWAL KIRAN , RUMMAN AASIA
Published: September 2023

Objective: Pre-eclampsia is a pregnancy disorder with hypertension and proteinuria. Abnormal placental development and maternal/fetal genetic factors contribute to its pathogenesis. Women with pre-eclampsia are at higher risk of chronic hypertension, emphasizing the importance of postnatal monitoring and preventive measures.

Methods: The study was conducted at the Department of Obstetrics and Gynaecology, Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital, New Delhi, from November 2017 to March 2019. Ethical clearance and informed consent were obtained. A total of 150 consecutive women with pre-eclampsia were included. Detailed history, clinical examination, and investigations were conducted. Women were followed until discharge and at 6 w postpartum. Determinants of persistent postpartum hypertension were compared between two groups, and statistical analysis was performed.

Results: This study aimed to investigate the clinical and biochemical determinants of persistent postpartum hypertension at 6 w in women with pre-eclampsia. A total of 125 out of 150 eligible women with pre-eclampsia were followed up at 6 w postpartum. Socio-demographic, clinical, obstetrical, and treatment-related parameters were analyzed, and logistic regression. A p-value of <0.05 was considered significant.

Conclusion: In conclusion, parity and previous history of hypertension consistently emerge as risk factors for persistent postpartum hypertension in women with pre-eclampsia, variations in the literature call for further research to reconcile discrepancies and enhance understanding.
SCREENING OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AMONG HEALTHCARE WORKERS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN IN A TERTIARY CARE HOSPITAL
Authors: BONANGI SRIVANI VIJAYA SUBHASHINI , BADAMPUDI S. S. VIJAYA SRI
Published: September 2023

Objective: Colonization of Staphylococcus aureus in the nasal flora has been proven to play an important role in the transmission of infections. Health care workers carrying Staphylococcus aureus in their nose or skin play an important role in cross-contamination and thus result in Methicillin-resistant Staphylococcus aureus (MRSA) related hospital-acquired or community-acquired infections. Implementation of hand hygiene methods and standard precautions are helpful in reducing transmission and controlling spread. Screening for carriage of MRSA is fundamental step in nosocomial infection control. The present study was undertaken to determine the prevalence of MRSA carriage rate and study their antibiogram.

Methods: A cross-sectional study was conducted for a period of six months and samples from 185 HCWs working in high-risk areas were processed by standard protocols. As per CLSI guidelines, MRSA detection by disc diffusion method using Cefoxitin disc (30μg) and further determined by Epsilometer test (E-test) by interpreting Minimum inhibitory concentration (MIC) values (mcg/ml).

Results: Out of 185 nasal swabs, 53 were Staphylococcus aureus isolates. MRSA colonization is seen in (8.64%) samples. Preponderance was seen in staff nurses (10.16%). Antibiogram of MRSA isolates showed sensitivity to Vancomycin and linezolid.

Conclusion: The present study was undertaken to screen nasal carriage of MRSA among healthcare workers, as they pose a potential risk factor for nosocomial transmission leading to MRSA outbreaks. The strengthening of Infection prevention and control measures institutionalization of antimicrobial stewardship programs helps in curbing the spread of MRSA.
ASSESSMENT OF DIFFERENT DOSES OF NEOSTIGMINE IN REVERSING CISATRACURIUM INDUCED NEUROMUSCULAR BLOCK BY USING NEUROMUSCULAR MONITOR: A PROSPECTIVE, DOUBLE-BLIND RANDOMIZED TRIAL
Authors: MODI YOGESH CHAND , SONI MANOJ KUMAR , CHARAN PRADEEP
Published: September 2023

Objective: This study aimed to evaluate the effectiveness of different reversal strategies with neostigmine in cisatracurium-induced neuromuscular blockade by, focusing on recovery times, incidence of residual blockade, and patient safety profile.
Methods: A prospective, randomized, double-blind trial was conducted involving six groups of patients (n=30 each) receiving different dosages of neostigmine at different TOF ratios. Neuromuscular function recovery, residual blockade incidence, and safety were assessed using various measurements. Statistical analysis included ANOVA, Chi-square tests, and post-hoc analyses.
Results: The study found that recovery times varied based on neostigmine dosages and train-of-four (TOF) ratios at the time of administration. The study groups exhibited varying mean times to achieve TOF ratios of 0.9 and 1.0 after neostigmine administration. The incidence of post-extubation TOF ratios below 0.9 showed no substantial variation among the groups. The overall incidence of adverse effects was low, with no significant differences observed among the study groups.
Conclusion: The study concludes that 30 mcg/kg administered at TOF ratio 0.6 may be the most effective dosage of neostigmine for rapid and sufficient recovery from shallow neuromuscular blockade at TOF ratio 0.4 or 0.6, with the fewest adverse effects. 20 mcg/kg is the lowest dose that can be used to successfully restore shallow neuromuscular block, albeit it does take longer time.
A COMPREHENSIVE AND PROSPECTIVE ANALYSIS TO IMPROVE PATIENT OUTCOMES IN POSTOPERATIVE PERIOD BY OPTIMIZING NEOSTIGMINE DOSE AND TIMING WITH THE HELP OF TOF MONITORING
Authors: MODI YOGESH CHAND , MEENA SAVITA , CHARAN PRADEEP
Published: September 2023

Objective: The objective is to find out the optimum neuromuscular reversal strategy using Train-of-Four (TOF) monitoring in the postoperative period for complete and risk-free recovery without residual paralysis. In this study, the neuromuscular blockade brought on by cisatracurium will be reversed using a neuromuscular monitor (TOF) and neostigmine administered at the best possible time and dose. In addition, we'll look at the prevalence of neuromuscular paralysis that persists after general anesthesia, as some research have revealed that paralysis may worsen and return once patients leave the recovery area.
Methods: A comprehensive prospective, randomized, double-blind and prospective analysis was conducted involving various study groups. Demographic data, residual neuromuscular weakness, negative head lift tests, and Visual Analog Scale (VAS) scores were assessed. TOF monitoring was used regularly to tailor neuromuscular reversal strategies.
Results: Incidence of regression of TOF ratio<0.9 and incidence of negative head lift test after extubation among different groups were statistically non-significant by Chi square test at 15 min (p value 0.4), 30 min (0.8) and 60 min (p value 0.9).
It also concludes that neuromuscular stimulation given for TOF monitoring is well tolerated by different group of the population in terms of VAS score (mean 3.9, ranging from 3.3 to 3.8).
Conclusion: This research suggests that tailoring strategies of neostigmine dose and time of its administration according to TOF ratio leads to complete recovery of neuromuscular function with all the doses (20/30/40 micrograms/kg). This study emphasizes the use of neuromuscular monitoring guided reversal methods to attain complete recovery without residual paralysis.
EpI-PUMA: Plataforma Universitaria de Inteligencia Epidemiológica de SARS-CoV-2, Versión 1.0
Authors: Salinas Medina Alejandro , García Peña Gabriel Ernesto , Gordillo José Luis , Calero Romel , Romero Martínez Pedro , Jurado Jiménez Karla , González Salazar Constantino , Rhodes Stephens Christopher
Published: September 2023

El avance en el espacio y tiempo de la COVID-19, en México y en el mundo, es difícil de predecir debido a un amplio espectro de factores; desde los biológicos a los asociados con la toma de decisiones en múltiples niveles, desde el personal hasta el gubernamental. Una forma de entender este fenómeno es analizando una gran cantidad de datos que describen condiciones y factores de la sociedad y sus interacciones. Si bien estos datos son públicos, y de fácil acceso, ¿qué puede hacer una persona con ellos? Para convertir los datos en una herramienta de interés público y de toma de decisiones podemos integrarlos a una plataforma que facilite construir y/o consultar modelos que extraigan la información pertinente de los datos disponibles. Este es el objetivo de EpI-PUMA: poner a disposición del público en general una plataforma pública de Servicio (“Platform-as-a-Service” - PaaS) que integra datos de diversa índole, y genera modelos adaptativos de aprendizaje de máquina, que facilitan el estudio y predicción del comportamiento de fenómenos epidemiológicos. Con el estudio de la pandemia de COVID-19 se sientan las bases de EpI-PUMA como PaaS orientado a la inteligencia epidemiológica.
Mutaciones duraderas para la educación superior. Los pizarrones virtuales y su rol en la colaboración remota durante la pandemia
Authors: Morales Zaragoza Nora A. , Ramírez Ramírez Ivonne Alejandra , Torres Cervantes Luz Margarita
Published: September 2023

El propósito de este artículo es comunicar la experiencia de enseñanza aprendizaje apoyada por el uso de plataformas de pizarrones virtuales como “Miro”. Estas herramientas que denominamos convergentes, ayudaron a mejorar el trabajo colaborativo y facilitaron la co-creación de un grupo de estudiantes de educación superior en el periodo de clases en modalidad remota durante la pandemia por la COVID-19. No se puede negar, que el confinamiento y la distancia social aceleraron los procesos digitales de varios sectores de la población, en este caso, la atención se centra en las nuevas plataformas de pizarrones virtuales como facilitadores de procesos colaborativos remotos, en el contexto de educación superior. Se describen algunas experiencias docentes puntuales, que junto con las herramientas del lenguaje visual lograron orquestar un mejor entendimiento y promover el trabajo colectivo de los estudiantes.
Intususcepción en adulto como complicación de un lipoma parietal intestinal. Reporte de caso
Authors: Rodríguez Sotto Leidi Johana , Murguía Lugo Emmanuel Francisco , Bucheli Buesaco Julián Andrés
Published: September 2023

Intussusception in adults is an extremely rare surgical clinical entity, its main etiology in this population is generally attri¬buted to malignant origin, benign pathology is less frequent and presents a challenge for pre-surgical diagnosis, since its presentation is non-specific and variable. Below is a clinical case that debuted with a clinical picture of intermittent pain in the right upper quadrant, manifesting exacerbation and non-specific laboratory tests, for which initially pathology of biliary origin was thought to be the reason for the pain, and therefore, an ultrasound of the liver and bile ducts was performed, observing signs suggestive of intussusception secondary to a lipoma, for which a simple abdominal tomography was performed to corroborate the diagnosis.
Keywords: Adult; intestinal obstruction; computed tomography; intussusception; intestinal lipoma.
El otro Ramón y Cajal
Authors: Fortoul Teresa I.
Published: September 2023

Santiago Ramón y Cajal had a brother, Pedro who has been ignored by History, hidden under the enormous shadow of its famous relative but also due to his humble and modest character. Both were decreed by their parents to be doctors, a profession to which they would arrive not without first going through many adventures
Experimental Study of Mechanical Behaviour of an RC Concrete Prepared Using M-Sand along with Chemical Admixtures
Authors: V Thirumoorthy , N Gokulnath , S Elaiyarasu
Published: September 2023

Abstract: Concrete plays a predominant role in the construction industry and a large quantum of sand is being utilized for various construction of structure. River sand has become expensive due to excessive cost of transportation from natural sources. Also, large- scale depletion of these sources creates environmental problems. So as to overcome, M- Sand can be an economic alternative to the river sand with respect to its availability, cost and environmental impact M-sand a by-product from the stone crushing unit which is released directly into environment can cause environmental pollution. And can be defined as residue, tailing or other non-voluble waste material after the extraction and processing of rocks to form fine particles. Recycling is the key component of modern waste management system and it reduce the consumption of fresh raw materials, reduce energy usage, reducing the need for conventional waste disposal and to lower greenhouse gas emission. To investigate the mechanical properties as compressive strength “Cubes” of size 150 mm x 150 mm x 150 mm are prepared, the Split tensile strength “cylinder” of size 750mm x 150 mm x 150 mm and also load deflection of beam and column are prepared and investigation should be carried out at a regular interval of 7,14 and 28 days. And also, the dynamic behavior is also studied. This present work is an attempt to use M-sand as a replacement (25%, 50%, 75% & 100%) for River Sand in M-30 Grade concrete mix.
Explore the Technological Advancements that will Shape the Future of 6G Networks
Authors: Dalmia Piyush , Singh Balpreet , Singh Harmanpreet
Published: September 2023

Abstract: The fifth generation, or 5G, mobile communication has been increasing steadily in most countries which mean that their market share is already very large. Thus, it is time for academia and industry to start thinking about the sixth generation (6G) of phones. The next world-changing technology will certainly be a topic of interest so an overview of what current technology is like and what future developments might occur would be very interesting. This research paper tries to provide a comprehensive understanding of what 6G might look like, what would be its technology requirements, what would be its use case scenarios, and what development has been made so far in this field. We will begin by trying to answer the question, “Do we really want 6G. To answer this question, we’ll look at the reasons why we’re looking forward to 6G. Next, we’ll look at the potential use cases of 6G, and all the new features that it will bring to the table. And lastly, we’ll look at its technological requirements.
The AI Galaxy: A Comparative Study of Cutting-Edge AI Technology
Authors: Shirodkar Sailee S. , Raotole Atharv N. , Gajbhiye Prof. Chandrashekhar R.
Published: September 2023

Abstract: The world of artificial intelligence (AI) has evolved into a vast array of technologies. The purpose of this paper is to explore a range of AI models and products, including GPT-4, GPT4-0613, GPT-3.5-Turbo, GPT-3.5-Turbo-0613, Claude-1, Claude-2, Claude-Instant-1, GPT-4-32K, GPT-4-32K-0613, GPT-3.5-Turbo-16K, GPT-3.5-Turbo-16K-0613, Claude-1-100K, Claude-1-100K, Claude-1-Instant-1-100K, Google BardAI, Microsoft Bing, and Perplexity. It will cover their capabilities, use cases, and what makes them unique in today's ever-expanding world of artificial intelligence. A comparison of these models and products will also be presented, highlighting the strengths and weaknesses of each.
Stabilization of Soil Using Guar Gum Biopolymer
Authors: Yogeshwar Krishna Chandra , Sonthwal Er. Vinod Kumar
Published: September 2023

Abstract: Soil stabilization in a broader sense refers to various methods and techniques employed to improve the geotechnical properties of a problematic soil to enhance its load bearing capacity. Many materials like cement, lime, bitumen etc. are employed to improve the properties but they are not ecofriendly as such. In this study, an effort has been made to study the effect of natural occurring polymer, Guar Gum to improve the mechanical properties of soil rich in clayey minerals. This biopolymer is biodegradable in nature and have less carbon footprint than other conventional materials. Five different varying proportion (0.5%, 1.0%, 1.75%, 2.50% and 3.25%) of Guar Gum with soil has been used to find the optimum dosage required for stabilization. Three major properties like Optimum Moisture Content -Maximum Dry Density relation, California Bearing Ratio Test (both unsoaked and soaked) and Unconfined Compressive Strength Test were studied on the soil and mixes. From the results it was concluded that soil with 1% Guar Gum has shown maximum improvement in the geotechnical properties of soil.
Study on Development of M20 and M25 Grades of Self Curing Concrete Using Formaldehyde and Sodium Polyacrylate
Authors: Sharma Er. Shubham , Sood Dr. Hemant , Rattan Sh. Jasvir Singh
Published: September 2023

Abstract: Self-curing concrete, a specialized solution, eliminates external curing for optimal performance in construction. It maintains internal moisture, reducing autogenous shrinkage and early-stage cracking. This innovative approach, promoting sustainable practices, is valuable for high-rise buildings and bridges. Self-Curing properties achieved in concrete through the incorporation of Sodium Polyacrylate and Formaldehyde. Extensive testing was conducted on diverse concrete samples to evaluate their properties, encompassing workability, compressive strength, tensile strength, and flexural strength. Sodium polyacrylate which is a super absorbent polymer is added to the concrete mix of M20 & M25 grade of concrete in variations (0%, 0.2%, 0.4%, 0.6%, 0.8%, 1.0%) by weight of cement. Formaldehyde added to concrete mix used as shrinkage reducing agent is added 1% with water. Light weight aggregate like brick chips replaced 10% of coarse aggregate are used because bricks absorb and holds a large amount so water. So pre-saturated brick chips are also used to provide internal curing. Sand is replaced by wood powder by 5%, as it also absorbs water. The compressive strength tests were carried out on M20 and M25 grade concretes with different water-cement ratios (for M20 w/c ratio is 0.50 & for M25 w/c ratio is 0.40), adhering to BIS: 516 – 1959 standards. The results indicated that the addition of sodium polyacrylate by weight of cement up to 0.6% led to optimal compressive strength values, beyond which further additions resulted in a decline in strength. Similarly, the split tensile strength tests for M20 and M25 grade concretes showcased the highest values at 0.6% addition of sodium polyacrylate by weight of cement. Subsequent increases in the additive led to a decrease in split tensile strength. Finally, the flexural strength tests for both M20 and M25 grade concretes yielded their highest values at 0.6% sodium polyacrylate by weight of cement, with diminishing flexural strength observed with higher additive percentages. These findings offer valuable insights into enhancing the self-curing properties of concrete and optimizing its characteristics by utilizing sodium polyacrylate as an additive.
The Impact of Gastrointestinal Health on the Omicron Variant Infection: from New-emerging and Pre-existing Gastrointestinal Injury
Authors: Liu Xinghuang , Luvsandagva Bayasgalan , Wang Dongke , Zhu Siran , Xu Zhiyue , Zhou Dan , Xie Xiaotian , Qian Wei , Hou Xiaohua , Bai Tao
Published: September 2023

Objective: This study focused on the gastrointestinal complains
in the Omicron variant infection and the related factors based on the
basic gut health status. Methods: A cross-sectional study was
conducted to included participants infected with Omicron variant. A
structured questionnaire was designed to collect their demographic
characteristics, gastrointestinal health status, and clinical
manifestation during the infection. Results: There were 11,484
questionnaires received from online platform. 7,929 questionnaires were
selected according to the inclusion and exclusion criteria. Among them
4,225 (53.3%) were females and the mean age was 36.0±8.8 years old. In
general, the proportion of GI complains in the Omicron variant infection
was 31.4% (62.6% and 25.0% in participants with pre-existing
gastrointestinal complains and those without, respectively). The
participants with pre-existing gastrointestinal complains exhibited more
severe clinical manifestations during infection compared to those
without. Notably, the participants with gastrointestinal complains
during the infection were associated with more severe clinical
manifestations irrespective of the basic gut health status. Upper,
rather than lower gastrointestinal complains were more closely
associated with the severity of the clinical manifestations.
Conclusion: Patients with gastrointestinal complains during the
Omicron variant infection were potential to experience more severe
clinical manifestations. Basic gastrointestinal health status is closely
related with the incidence of gastrointestinal complains and the
severity of the clinical manifestations.
Optimal Management of Severe Mpox in Patients with Uncontrolled HIV
Authors: Shishido Akira , Street Stacy
Published: September 2023

In May 2022, a cluster of non-travel-related cases of human mpox were
reported in the UK. The outbreak has since spread world-wide infecting
over 85,000 patients and causing over 100 deaths. Recent data clearly
suggest that patients infected with Human Immunodeficiency Virus (HIV)
with CD4 counts less than 200 cells per mm suffer
significantly worse outcomes than immunocompetent patients. The
available countermeasures lack robust clinical data and are deployed
based on in vitro and animal studies as well as extrapolations
from use against other poxviruses. In many cases, despite administration
of these available treatments, initiation of antiretroviral therapy, and
management of Immune Reconstitution Inflammatory Syndrome (IRIS),
patients die. This review summarizes available data, identifies
knowledge gaps and proposes recommendations on the management of severe
mpox in PLWH.
Mitochondrial DNA survival in leather /leather products and Taqman based PCR assay explores the credibility of identification: An approach on Ovis aries (Indian)
Authors: Pavithra N , Felshia S Chris , Sundar V John , GNANAMANI A
Published: September 2023

Leather and leather products are the most traded commodities and play a
significant role in the world’s economy. The traditional tanning methods
and the high quality of Indian leathers receive global appreciation. The
existing leather manufacturing methods made a significant loss in
epidermal constituents which impact the commercial importance of the
animal species. Embossing techniques could potentially contribute to an
increase in fraudulent activities. Since the fate of genetic material in
finished leather is questionable, which poses a challenge to the
molecular approach for identification. In order to obviate the problem,
the present study aims to recover amplifiable mtDNA from leather
products and focus on developing probes and primers for RT-PCR, which
significantly enhance cross-specificity. Data mining and phylogenetic
analyses of mtDNA genes (12S rRNA, COI, and Cyt b) for Indian Ovis aries
skins exhibit the taxonomic positions and the intraspecies
relationships, thereby facilitating the probes desigining. The results
indicate that the maximum intraspecies genetic divergence observed
within 12S rRNA, followed by COI and Cyt b. Since the availability of
genetic sequences with reference to Cyt b is comparatively large (602),
primers and probes were designed for Cyt b. The RT-PCR analysis of
finished Ovis aries leather mtDNA samples yield a ct value in the range
of 22–23 cycles, even with a minimum quantity of template DNA as low as
0.3 ng. Results on the cross-specificity analysis are highly
encouraging. Hence, it is feasible to identify genuine Ovis aries
leather using mtDNA instilling confidence in the export of leather.
Optimization Strategy for Response Power-Carbon Emission Quota Coupled Trading Among IESPs in Complex Scenarios
Authors: Xu Gang , Guo Zixuan , Zheng Shunlin
Published: September 2023

Integrated Demand Response (IDR) as a crucial method for maintaining
supply-demand balance and realizing the local consumption of distributed
energy in Regional Integrated Energy System (RIES), has become a hot
research topic. However, existing studies on IDR have two main
shortcomings: they fail to consider the coupling relationship between
response power and carbon emission quota in complex scenarios during
regional transactions; and when customizing incentive strategies for
consumers within regions, they overlook the fatigue characteristics of
consumers. Therefore, this paper establishes an inter-regional coupled
transaction mechanism of response power-carbon emission quota under
complex scenarios. The incorporation of a response fatigue function
enables the proficient representation of consumer response fatigue
characteristics. Additionally, this paper proposes an adaptive iterative
step size-based bargaining method to determine the optimal transaction
price. The effectiveness of the proposed model is verified by simulation
results: it not only reduces the total costs and carbon emission of IESP
but also improves consumer benefits. The proposed bargaining method
enhances bargaining efficiency.