bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from Numb Regulates Stability and Localization of the Mitotic Kinase PLK1 and Is Required for Transit through Mitosis
Authors: Schmit Travis L. , Nihal Minakshi , Ndiaye Mary , Setaluri Vijayasaradhi , Spiegelman Vladimir S. , Ahmad Nihal
Published: March 2023

PDF file - 150K, To determine if the changes seen in Plk1 stability were an indirect consequence of Numb's other roles we treated A375 cells with nonsense (NS) or Numb targeting shRNA in the presence of luciferase plasmids to measure the transcriptional activity of Notch (Hes-Luciferase), p53 (p21-Luciferase), or Hedgehog (Gli-Luciferase) signaling. Data is normalized to beta-galactosidase activity
Supplementary Figure 1 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 235K, Gene Set Enrichment Analysis output for top KEGG pathways and GO biological process (GOBP) terms that are associated with high CCL5/CCR5 coexpression
Supplementary Figure 2 from Fra-1 Promotes Breast Cancer Chemosensitivity by Driving Cancer Stem Cells from Dormancy
Authors: Lu Dan , Chen Si , Tan Xiaoyue , Li Na , Liu Chenghu , Li Zongjin , Liu Ze , Stupack Dwayne G. , Reisfeld Ralph A. , Xiang Rong
Published: March 2023

PDF file - 75K, Cell proliferation was evaluated by staining of Ki-67 and Ki-67 expression in 4TO7-Fra-1 cells (A) as well as 4TO7-sh1 and 4TO7-sh2 cells (B) was measured by FACS. The expression of Ki-67 was quantified by mean fluorescence intensity. Error bars represent mean � SD, #p=0.12, *p <0.05, versus control group
Supplementary Figure 6 from Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Authors: Sisirak Vanja , Faget Julien , Gobert Michael , Goutagny Nadège , Vey Nelly , Treilleux Isabelle , Renaudineau Sarah , Poyet Gaelle , Labidi-Galy Sana Intidhar , Goddard-Leon Sophie , Durand Isabelle , Le Mercier Isabelle , Bajard Agathe , Bachelot Thomas , Puisieux Alain , Puisieux Isabelle , Blay Jean-Yves , Ménétrier-Caux Christine , Caux Christophe , Bendriss-Vermare Nathalie
Published: March 2023

PDF file, 46K, Purified healthy pDC were cultured with IL-3 either alone or in combination with 25% of TUMSN for 40 h and then incubated for 5 days with allogeneic naive CD4+ T cells.
Supplementary Figure 2 from Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Authors: Sisirak Vanja , Faget Julien , Gobert Michael , Goutagny Nadège , Vey Nelly , Treilleux Isabelle , Renaudineau Sarah , Poyet Gaelle , Labidi-Galy Sana Intidhar , Goddard-Leon Sophie , Durand Isabelle , Le Mercier Isabelle , Bajard Agathe , Bachelot Thomas , Puisieux Alain , Puisieux Isabelle , Blay Jean-Yves , Ménétrier-Caux Christine , Caux Christophe , Bendriss-Vermare Nathalie
Published: March 2023

PDF file, 67K, Identification of pDC and mDC in blood and tissues.
Supplementary Figure 1 from Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Authors: Sisirak Vanja , Faget Julien , Gobert Michael , Goutagny Nadège , Vey Nelly , Treilleux Isabelle , Renaudineau Sarah , Poyet Gaelle , Labidi-Galy Sana Intidhar , Goddard-Leon Sophie , Durand Isabelle , Le Mercier Isabelle , Bajard Agathe , Bachelot Thomas , Puisieux Alain , Puisieux Isabelle , Blay Jean-Yves , Ménétrier-Caux Christine , Caux Christophe , Bendriss-Vermare Nathalie
Published: March 2023

PDF file, 114K, Overall survival and relapse-free survival of patients according to the presence of CD123+ pDC in primary breast carcinoma.
Supplementary Table 3 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

PDF file - 64K, PDGFR� immunostaining of tissue blocks
Supplementary Figure 1 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

PDF file - 259K, Receptor of tyrosine kinases phosphorylation in sarcoma cell lines
Supplementary Figure 3 from Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma
Authors: Wondergem Bill , Zhang Zhongfa , Huang Dachuan , Ong Choon Kiat , Koeman Julie , Hof David Van't , Petillo David , Ooi Aikseng , Anema John , Lane Brian , Kahnoski Richard J. , Furge Kyle A. , Teh Bin Tean
Published: March 2023

PDF file, 278K, Supplemental Figure S3. Direct targeting of ECT2 by siRNA results in a dose-dependent inhibition of ccRCC cell growth. (a) MTS proliferation assays showed a dose-dependent reduction in 786-O cell growth upon treatment with siRNA's targeting ECT2. (b) Depletion of ECT2 results in an accumulation of cells in G2/M phase. (c) Cells unable to complete cell division acquired a multinucleate phenotype, indicative of cytokinesis defects upon ECT2 knockdown.
Supplementary Methods from p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
Authors: Livesey Kristen M. , Kang Rui , Vernon Philip , Buchser William , Loughran Patricia , Watkins Simon C. , Zhang Lin , Manfredi James J. , Zeh Herbert J. , Li Luyuan , Lotze Michael T. , Tang Daolin
Published: March 2023

PDF file - 324K
Supplementary Figure 4 from DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial–Mesenchymal Transition in Human Breast Cancer
Authors: Lv Qi , Wang Wei , Xue Jianfei , Hua Fang , Mu Rong , Lin Heng , Yan Jun , Lv Xiaoxi , Chen Xiaoguang , Hu Zhuo-Wei
Published: March 2023

PDF file - 228K, Knockdown of DEDD stabilizes Twist through attenuating the autophagy-lysosome degradation system
Supplementary Table 3B from Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis
Authors: Ganti Sheila , Taylor Sandra L. , Abu Aboud Omran , Yang Joy , Evans Christopher , Osier Michael V. , Alexander Danny C. , Kim Kyoungmi , Weiss Robert H.
Published: March 2023

XLS file - 23K, All identified metabolites in serum
Supplementary Figure 2 from DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial–Mesenchymal Transition in Human Breast Cancer
Authors: Lv Qi , Wang Wei , Xue Jianfei , Hua Fang , Mu Rong , Lin Heng , Yan Jun , Lv Xiaoxi , Chen Xiaoguang , Hu Zhuo-Wei
Published: March 2023

PDF file - 278K, DEDD regulates proliferation and apoptosis in breast cancer cells
Supplementary Table 3A from Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis
Authors: Ganti Sheila , Taylor Sandra L. , Abu Aboud Omran , Yang Joy , Evans Christopher , Osier Michael V. , Alexander Danny C. , Kim Kyoungmi , Weiss Robert H.
Published: March 2023

XLS file - 27K, All identified metabolites in tissue
Supplementary Table 2 from Suppression of Tak1 Promotes Prostate Tumorigenesis
Authors: Wu Min , Shi Lihong , Cimic Adela , Romero Lina , Sui Guangchao , Lees Cynthia J. , Cline J. Mark , Seals Darren F. , Sirintrapun Joseph S. , McCoy Thomas P. , Liu Wennuan , Kim Jin Woo , Hawkins Gregory A. , Peehl Donna M. , Xu Jianfeng , Cramer Scott D.
Published: March 2023

PDF file - 6K, Primer sequences for detecting expression of the 5 genes within the consensus deletion regions in WFU3 cells.
Supplementary Figure 2 from Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Authors: Sceneay Jaclyn , Chow Melvyn T. , Chen Anna , Halse Heloise M. , Wong Christina S.F. , Andrews Daniel M. , Sloan Erica K. , Parker Belinda S. , Bowtell David D. , Smyth Mark J. , Möller Andreas
Published: March 2023

PDF file - 221K, A) Pre-metastatic niche induced by hypoxia increases melanoma metastasis. B) Factors identified in HCM of breast cancer cells
Supplementary Figure 3 from Suppression of Tak1 Promotes Prostate Tumorigenesis
Authors: Wu Min , Shi Lihong , Cimic Adela , Romero Lina , Sui Guangchao , Lees Cynthia J. , Cline J. Mark , Seals Darren F. , Sirintrapun Joseph S. , McCoy Thomas P. , Liu Wennuan , Kim Jin Woo , Hawkins Gregory A. , Peehl Donna M. , Xu Jianfeng , Cramer Scott D.
Published: March 2023

PDF file - 1MB, Suppression of Tak1 promotes scatter growth of shTak1 PrP/SCs.
Supplementary Figure 7 from ATR–ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway
Authors: Shigechi Tomoko , Tomida Junya , Sato Koichi , Kobayashi Masahiko , Eykelenboom John K. , Pessina Fabio , Zhang Yanbin , Uchida Emi , Ishiai Masamichi , Lowndes Noel F. , Yamamoto Kenichi , Kurumizaka Hitoshi , Maehara Yoshihiko , Takata Minoru
Published: March 2023

PDF file - 1.3MB
Supplementary Figure 6 from ATR–ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway
Authors: Shigechi Tomoko , Tomida Junya , Sato Koichi , Kobayashi Masahiko , Eykelenboom John K. , Pessina Fabio , Zhang Yanbin , Uchida Emi , Ishiai Masamichi , Lowndes Noel F. , Yamamoto Kenichi , Kurumizaka Hitoshi , Maehara Yoshihiko , Takata Minoru
Published: March 2023

PDF file - 987K
Supplementary Figure 4 from AMPK Promotes p53 Acetylation via Phosphorylation and Inactivation of SIRT1 in Liver Cancer Cells
Authors: Lee Chi-Wai , Wong Leo Lap-Yan , Tse Edith Yuk-Ting , Liu Heong-Fai , Leong Veronica Yee-Law , Lee Joyce Man-Fong , Hardie D. Grahame , Ng Irene Oi-Lin , Ching Yick-Pang
Published: March 2023

PDF file - 99K, SirT1 T344E mutant was defective in p53 deacetylase activity
Supplementary Figure 2 from ATR–ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway
Authors: Shigechi Tomoko , Tomida Junya , Sato Koichi , Kobayashi Masahiko , Eykelenboom John K. , Pessina Fabio , Zhang Yanbin , Uchida Emi , Ishiai Masamichi , Lowndes Noel F. , Yamamoto Kenichi , Kurumizaka Hitoshi , Maehara Yoshihiko , Takata Minoru
Published: March 2023

PDF file - 5.7MB
Supplementary Figure 1 from Accumulation of Multipotent Progenitors with a Basal Differentiation Bias during Aging of Human Mammary Epithelia
Authors: Garbe James C. , Pepin Francois , Pelissier Fanny A. , Sputova Klara , Fridriksdottir Agla J. , Guo Diana E. , Villadsen Rene , Park Morag , Petersen Ole W. , Borowsky Alexander D. , Stampfer Martha R. , LaBarge Mark A.
Published: March 2023

PDF file - 326K, Cultured pre-stasis finite lifespan HMEC at early passage preserve key features of HMEC in vivo
Supplementary Table 3 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Authors: Liu Xiyong , Lai Lily , Wang Xiaochen , Xue Lijun , Leora Sofia , Wu Jun , Hu Shuya , Zhang Keqiang , Kuo Mei-Ling , Zhou Lun , Zhang Hang , Wang Yafan , Wang Yan , Zhou Bingsen , Nelson Rebecca A. , Zheng Shu , Zhang Suzhan , Chu Peiguo , Yen Yun
Published: March 2023

Supplementary Table 3 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Supplementary Table 2 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Authors: Liu Xiyong , Lai Lily , Wang Xiaochen , Xue Lijun , Leora Sofia , Wu Jun , Hu Shuya , Zhang Keqiang , Kuo Mei-Ling , Zhou Lun , Zhang Hang , Wang Yafan , Wang Yan , Zhou Bingsen , Nelson Rebecca A. , Zheng Shu , Zhang Suzhan , Chu Peiguo , Yen Yun
Published: March 2023

Supplementary Table 2 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Supplementary Table 1 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Authors: Liu Xiyong , Lai Lily , Wang Xiaochen , Xue Lijun , Leora Sofia , Wu Jun , Hu Shuya , Zhang Keqiang , Kuo Mei-Ling , Zhou Lun , Zhang Hang , Wang Yafan , Wang Yan , Zhou Bingsen , Nelson Rebecca A. , Zheng Shu , Zhang Suzhan , Chu Peiguo , Yen Yun
Published: March 2023

Supplementary Table 1 from Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
Supplementary Table 2 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: March 2023

XLS file - 8K, describing KEGG pathway analysis results
Supplementary Table 1 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa
Authors: Ng Yi-Zhen , Pourreyron Celine , Salas-Alanis Julio C. , Dayal Jasbani H.S. , Cepeda-Valdes Rodrigo , Yan Wenfei , Wright Sheila , Chen Mei , Fine Jo-David , Hogg Fiona J. , McGrath John A. , Murrell Dedee F. , Leigh Irene M. , Lane E. Birgit , South Andrew P.
Published: March 2023

XLS file - 36K, Table describing the patient samples used in this study
Supplementary Figure Legends 1-3 from FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy
Authors: Li Zhoulei , Graf Nicolas , Herrmann Ken , Jünger Alexandra , Aichler Michaela , Feuchtinger Annette , Baumgart Anja , Walch Axel , Peschel Christian , Schwaiger Markus , Buck Andreas , Keller Ulrich , Dechow Tobias
Published: March 2023

PDF file - 101K
Supplementary Figure 4 from BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy
Authors: Koya Richard C. , Mok Stephen , Otte Nicholas , Blacketor Kevin J. , Comin-Anduix Begonya , Tumeh Paul C. , Minasyan Aspram , Graham Nicholas A. , Graeber Thomas G. , Chodon Thinle , Ribas Antoni
Published: March 2023

PDF file - 77K, 18FFAC PET imaging of adoptively transferred splenocytes with or without vemurafenib
Supplementary Figure 3 from BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy
Authors: Koya Richard C. , Mok Stephen , Otte Nicholas , Blacketor Kevin J. , Comin-Anduix Begonya , Tumeh Paul C. , Minasyan Aspram , Graham Nicholas A. , Graeber Thomas G. , Chodon Thinle , Ribas Antoni
Published: March 2023

PDF file - 109K, Effects of vemurafenib on the systemic distribution of adoptively transferred pmel-1 splenocytes
Supplementary Figure 6 from Collaboration of Kras and Androgen Receptor Signaling Stimulates EZH2 Expression and Tumor-Propagating Cells in Prostate Cancer
Authors: Cai Houjian , Memarzadeh Sanaz , Stoyanova Tanya , Beharry Zanna , Kraft Andrew S. , Witte Owen N.
Published: March 2023

PDF file, 91K, Sphere formation of normal primary prostate cells is suppressed by DZNep.
Supplementary Figure 2 from Collaboration of Kras and Androgen Receptor Signaling Stimulates EZH2 Expression and Tumor-Propagating Cells in Prostate Cancer
Authors: Cai Houjian , Memarzadeh Sanaz , Stoyanova Tanya , Beharry Zanna , Kraft Andrew S. , Witte Owen N.
Published: March 2023

PDF file, 157K, IHC analysis of regenerated tissues.
Supplementary Figure 3 from Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
Authors: Poage Graham M. , Butler Rondi A. , Houseman E. Andrés , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Marsit Carmen J. , Kelsey Karl T.
Published: March 2023

PDF file - 93K, Validation of array CpG methylation data by pyrosequencing
Supplementary Figure 2 from Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
Authors: Poage Graham M. , Butler Rondi A. , Houseman E. Andrés , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Marsit Carmen J. , Kelsey Karl T.
Published: March 2023

PDF file - 44K, Comparison of hyper- and hypomethylated CpG loci among each of the patient methylation subgroups
Supplementary Figure 3 from Targeting eNOS in Pancreatic Cancer
Authors: Lampson Benjamin L. , Kendall S. DiSean , Ancrile Brooke B. , Morrison Meghan M. , Shealy Michael J. , Barrientos Katharine S. , Crowe Matthew S. , Kashatus David F. , White Rebekah R. , Gurley Susan B. , Cardona Diana M. , Counter Christopher M.
Published: March 2023

PDF file - 164K, L-NAME has minimal effects on cellular proliferation in vitro
Supplementary Figure 1 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: March 2023

PDF file - 28K
Supplementary Table 5 from ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features
Authors: Albino Domenico , Longoni Nicole , Curti Laura , Mello-Grand Maurizia , Pinton Sandra , Civenni Gianluca , Thalmann George , D'Ambrosio Gioacchino , Sarti Manuela , Sessa Fausto , Chiorino Giovanna , Catapano Carlo V. , Carbone Giuseppina M.
Published: March 2023

XLS file - 142K, Genes up- and down- regulated in ESE3low tumors compared to all tumors (Q<0.05)
Supplementary Figures 1-7 from The T-cell Receptor Repertoire of Tumor-Infiltrating Regulatory T Lymphocytes Is Skewed Toward Public Sequences
Authors: Sainz-Perez Alexander , Lim Annick , Lemercier Brigitte , Leclerc Claude
Published: March 2023

PDF file - 10MB, Figures S1-S5 present the strategy of analysis and purification of tumor-infiltrating Treg and Teff cells as well as their phenotypes and BV - BJ usage. The Figures S6-S7 present the qualitative spectratyping analysis of CDR3 length profiles of T cells obtained from TC-1 and MO-5 tumor-bearing mice.
Supplementary Figure 5 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4
Authors: Srivastava Ratika , Geng Degui , Liu Yingjia , Zheng Liqin , Li Zhaoyang , Joseph Mary Ann , McKenna Colleen , Bansal Navneeta , Ochoa Augusto , Davila Eduardo
Published: March 2023

PDF file - 144K, Effects of TLR stimulation and cytokines on IRAK phosphorylation in melanoma cells
Supplementary Figures 1-7 from Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors
Authors: Rottenberg Sven , Vollebergh Marieke A. , de Hoon Bas , de Ronde Jorma , Schouten Philip C. , Kersbergen Ariena , Zander Serge A.L. , Pajic Marina , Jaspers Janneke E. , Jonkers Martijn , Lodén Martin , Sol Wendy , van der Burg Eline , Wesseling Jelle , Gillet Jean-Pierre , Gottesman Michael M. , Gribnau Joost , Wessels Lodewyk , Linn Sabine C. , Jonkers Jos , Borst Piet
Published: March 2023

PDF file - 751K
Supplementary Table 2 from SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression
Authors: Zhang Jianchao , Liang Qian , Lei Yang , Yao Min , Li Lili , Gao Xiaoge , Feng Jingxin , Zhang Yu , Gao Hongwen , Liu Dong-Xu , Lu Jun , Huang Baiqu
Published: March 2023

PDF file - 157K, New data of Oncomine analysis of SOX4 expression in human breast cancer
Supplementary Figure 5 from SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression
Authors: Zhang Jianchao , Liang Qian , Lei Yang , Yao Min , Li Lili , Gao Xiaoge , Feng Jingxin , Zhang Yu , Gao Hongwen , Liu Dong-Xu , Lu Jun , Huang Baiqu
Published: March 2023

PDF file - 3.6MB, Silencing of SOX4 in MDA-MB-231 and BT549 cells inhibited their invasive ability
Supplementary Tables 2-3 from Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity
Authors: Shoshani Ofer , Massalha Hassan , Shani Nir , Kagan Sivan , Ravid Orly , Madar Shalom , Trakhtenbrot Luba , Leshkowitz Dena , Rechavi Gideon , Zipori Dov
Published: March 2023

PDF file - 55K, Cytogenetic profile of cells used in the study and details of their tumorigenic properties
Supplementary Figure 2 from Glutamine Deprivation Enhances Antitumor Activity of 3-Bromopyruvate through the Stabilization of Monocarboxylate Transporter-1
Authors: Cardaci Simone , Rizza Salvatore , Filomeni Giuseppe , Bernardini Roberta , Bertocchi Fabio , Mattei Maurizio , Paci Maurizio , Rotilio Giuseppe , Ciriolo Maria Rosa
Published: March 2023

PDF file - 147K, Autophagy contributes to the execution of 3-BrPA-induced cell death upon glutamine withdrawal
Supplementary Table 6B from B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer
Authors: Wang Jingqiang , Kobayashi Takashi , Floc'h Nicolas , Kinkade Carolyn Waugh , Aytes Alvaro , Dankort David , Lefebvre Celine , Mitrofanova Antonina , Cardiff Robert D. , McMahon Martin , Califano Andrea , Shen Michael M. , Abate-Shen Cory
Published: March 2023

PDF file - 31K, Myc pathway enrichment analysis for differentially expressed genes between RAP + PD treated and Vehicle treated Nkx3.1CE2/+; Ptenf/f; BrafCA/+ mouse prostate tumors
Supplementary Table 6A from B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer
Authors: Wang Jingqiang , Kobayashi Takashi , Floc'h Nicolas , Kinkade Carolyn Waugh , Aytes Alvaro , Dankort David , Lefebvre Celine , Mitrofanova Antonina , Cardiff Robert D. , McMahon Martin , Califano Andrea , Shen Michael M. , Abate-Shen Cory
Published: March 2023

PDF file - 29K, Myc pathway enrichment analysis for differentially expressed genes between Nkx3.1CE2/+; Ptenf/f; BrafCA/+ and Nkx3.1CE2/+; Ptenf/f mouse prostate tumors
Supplementary Table 1 from Colorectal Cancer Risk Associated with Hormone Use Varies by Expression of Estrogen Receptor-β
Authors: Rudolph Anja , Toth Csaba , Hoffmeister Michael , Roth Wilfried , Herpel Esther , Schirmacher Peter , Brenner Hermann , Chang-Claude Jenny
Published: March 2023

PDF file - 108K, Distribution of selected risk determinants for colorectal cancer among female patients according to availability of classifiable tumor tissue.
Supplementary Table 5A from B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer
Authors: Wang Jingqiang , Kobayashi Takashi , Floc'h Nicolas , Kinkade Carolyn Waugh , Aytes Alvaro , Dankort David , Lefebvre Celine , Mitrofanova Antonina , Cardiff Robert D. , McMahon Martin , Califano Andrea , Shen Michael M. , Abate-Shen Cory
Published: March 2023

PDF file - 57K, Pathway enrichment analysis for differentially expressed genes between Nkx3.1CE2/+; Ptenf/f; BrafCA/+ and Nkx3.1CE2/+; Ptenf/f mouse prostate tumors
Supplementary Figure 2 from Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis
Authors: Low-Marchelli Janine M. , Ardi Veronica C. , Vizcarra Edward A. , van Rooijen Nico , Quigley James P. , Yang Jing
Published: March 2023

PDF file - 209K, Twist1 specifically induces the expression of CCL2, but not other angiogenic factors, such as VEGF and bFGF.
Supplementary Figure 1 from Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis
Authors: Low-Marchelli Janine M. , Ardi Veronica C. , Vizcarra Edward A. , van Rooijen Nico , Quigley James P. , Yang Jing
Published: March 2023

PDF file - 66K, Expression of Twist1 in HMLE cells.
Supplementary Methods and Materials and Figure Legends from Inhibition of c-Met Reduces Lymphatic Metastasis in RIP-Tag2 Transgenic Mice
Authors: Sennino Barbara , Ishiguro-Oonuma Toshina , Schriver Brian J. , Christensen James G. , McDonald Donald M.
Published: March 2023

PDF - 109K, Supplementary Methods and Materials and Supplementary Figure Legends for Supplementary Figures 1-4
Supplementary Figure 1 from NF-κB Activity Regulates Mesenchymal Stem Cell Accumulation at Tumor Sites
Authors: Uchibori Ryosuke , Tsukahara Tomonori , Mizuguchi Hiroyuki , Saga Yasushi , Urabe Masashi , Mizukami Hiroaki , Kume Akihiro , Ozawa Keiya
Published: March 2023

PDF file - 96K, Characterization of cultured human MSC
Supplementary Table 1 from KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells
Authors: Berry William L. , Janknecht Ralf
Published: March 2023

PDF file - 41K, Supplementary Table 1 showing KDM4 expression in tumors.
Supplementary Figure 3 from Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases
Authors: Riese Matthew J. , Wang Liang-Chuan S. , Moon Edmund K. , Joshi Rohan P. , Ranganathan Anjana , June Carl H. , Koretzky Gary A. , Albelda Steven M.
Published: March 2023

PDF file - 73K, Similar expression of Granzyme B and perforin in dgk-deficient mesoCAR T cells
Supplementary Figure 1 from Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer
Authors: Hartikainen Jaana M. , Tengström Maria , Kosma Veli-Matti , Kinnula Vuokko L. , Mannermaa Arto , Soini Ylermi
Published: March 2023

PDF file - 40K, A diagram depicting the genetic location of the studied SNPs in the NRF2 and SRXN1 genes
Supplementary Methods, Tables 1-4, Figures 1-11 from Monofunctional Platinum–DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
Authors: Zhu Guangyu , Myint MyatNoeZin , Ang Wee Han , Song Lina , Lippard Stephen J.
Published: March 2023

PDF file - 810K
Supplementary Table 9 from β-Catenin/POU5F1/SOX2 Transcription Factor Complex Mediates IGF-I Receptor Signaling and Predicts Poor Prognosis in Lung Adenocarcinoma
Authors: Xu Chuan , Xie Dan , Yu Shi-Cang , Yang Xiao-Jun , He Li-Ru , Yang Jing , Ping Yi-Fang , Wang Bin , Yang Lang , Xu Sen-Lin , Cui Wei , Wang Qing-Liang , Fu Wen-Juan , Liu Qing , Qian Cheng , Cui You-Hong , Rich Jeremy N. , Kung Hsiang-Fu , Zhang Xia , Bian Xiu-Wu
Published: March 2023

Supplementary Table 9 PDF file 167K, Supplementary Table 9. Clinicopathological features and IHC staining index of ALDH1A1, IGF-1R, �-catenin and POU5F1 in 200 patients with LAC
Supplementary Table 2 from RORα Suppresses Breast Tumor Invasion by Inducing SEMA3F Expression
Authors: Xiong Gaofeng , Wang Chi , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: March 2023

PDF file - 53K
Supplementary Table 1 from RORα Suppresses Breast Tumor Invasion by Inducing SEMA3F Expression
Authors: Xiong Gaofeng , Wang Chi , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: March 2023

PDF file - 81K
Supplementary Table 5 from Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
Authors: Geiger Tamar , Madden Stephen F. , Gallagher William M. , Cox Juergen , Mann Matthias
Published: March 2023

PDF file - 43K
Supplementary Table 4 from Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
Authors: Geiger Tamar , Madden Stephen F. , Gallagher William M. , Cox Juergen , Mann Matthias
Published: March 2023

XLS file - 73K
Supplementary Table 3 from Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
Authors: Geiger Tamar , Madden Stephen F. , Gallagher William M. , Cox Juergen , Mann Matthias
Published: March 2023

XLS file - 2.5MB
Supplementary Figure 1 from RORα Suppresses Breast Tumor Invasion by Inducing SEMA3F Expression
Authors: Xiong Gaofeng , Wang Chi , Evers B. Mark , Zhou Binhua P. , Xu Ren
Published: March 2023

PDF file - 1.3MB
Supplementary Methods from Proteomic Portrait of Human Breast Cancer Progression Identifies Novel Prognostic Markers
Authors: Geiger Tamar , Madden Stephen F. , Gallagher William M. , Cox Juergen , Mann Matthias
Published: March 2023

PDF file - 268K
Supplementary Table 3 from Extensive Promoter DNA Hypermethylation and Hypomethylation Is Associated with Aberrant MicroRNA Expression in Chronic Lymphocytic Leukemia
Authors: Baer Constance , Claus Rainer , Frenzel Lukas P. , Zucknick Manuela , Park Yoon Jung , Gu Lei , Weichenhan Dieter , Fischer Martina , Pallasch Christian Philipp , Herpel Esther , Rehli Michael , Byrd John C. , Wendtner Clemens-Martin , Plass Christoph
Published: March 2023

PDF file - 166K, Table S3 contains all putative promoter regions as determined by H3K4me3 enrichment
Supplementary Figures 1-5 from Extensive Promoter DNA Hypermethylation and Hypomethylation Is Associated with Aberrant MicroRNA Expression in Chronic Lymphocytic Leukemia
Authors: Baer Constance , Claus Rainer , Frenzel Lukas P. , Zucknick Manuela , Park Yoon Jung , Gu Lei , Weichenhan Dieter , Fischer Martina , Pallasch Christian Philipp , Herpel Esther , Rehli Michael , Byrd John C. , Wendtner Clemens-Martin , Plass Christoph
Published: March 2023

PDF file - 90K, Supplementary Figure S1 contains technical validations of differentially methylated miRNA promoters by high resolution quantitative DNA methylation analysis. Supplementary Figure S2 shows experimental validation of promoter activity for the mir-129-2 locus. Supplementary Figure S3 shows relative expression of predicted miRNA target genes by qPCR in CLL specimens and healthy B cell controls. Supplementary Figure S4 shows an unsupervised clustering of quantitative DNA methylation data at the identified hyper- and hypomethylated miRNA promoters in CLL specimens, healthy B cell samples, various normal hematopoietic cells and several solid tissues. Supplementary Figure S5 shows a detailed quantitative DNA methylation analysis of the miR-155 host gene 5' region and correlations with miR-155 expression in CLL specimens, healthy B cell samples, various normal hematopoietic cells and several solid tissues
Supplementary Table 1 from Unphosphorylated STAT1 Promotes Sarcoma Development through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance
Authors: Zimmerman Mary A. , Rahman Nur-Taz , Yang Dafeng , Lahat Guy , Lazar Alexander J. , Pollock Raphael E. , Lev Dina , Liu Kebin
Published: March 2023

PDF file - 81K, STS Patients Summary Information
Supplementary Table 1 from Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
Authors: Wong Christina S.F. , Sceneay Jaclyn , House Colin M. , Halse Heloise M. , Liu Mira C.P. , George Joshy , Hunnam Titaina C.U. Potdevin , Parker Belinda S. , Haviv Izhak , Ronai Ze'ev , Cullinane Carleen , Bowtell David D. , Möller Andreas
Published: March 2023

PDF file - 50K
Supplementary Figure 6 from Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
Authors: Wong Christina S.F. , Sceneay Jaclyn , House Colin M. , Halse Heloise M. , Liu Mira C.P. , George Joshy , Hunnam Titaina C.U. Potdevin , Parker Belinda S. , Haviv Izhak , Ronai Ze'ev , Cullinane Carleen , Bowtell David D. , Möller Andreas
Published: March 2023

PDF file - 118K
Supplementary Figure 5 from Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
Authors: Wong Christina S.F. , Sceneay Jaclyn , House Colin M. , Halse Heloise M. , Liu Mira C.P. , George Joshy , Hunnam Titaina C.U. Potdevin , Parker Belinda S. , Haviv Izhak , Ronai Ze'ev , Cullinane Carleen , Bowtell David D. , Möller Andreas
Published: March 2023

PDF file - 228K
Supplementary Figure 4 from Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells
Authors: Shien Kazuhiko , Toyooka Shinichi , Yamamoto Hiromasa , Soh Junichi , Jida Masaru , Thu Kelsie L. , Hashida Shinsuke , Maki Yuho , Ichihara Eiki , Asano Hiroaki , Tsukuda Kazunori , Takigawa Nagio , Kiura Katsuyuki , Gazdar Adi F. , Lam Wan L. , Miyoshi Shinichiro
Published: March 2023

PDF file - 283K, ALDH1A1 expression in xenograft tumors established from HCC827-GR-highs.
Supplementary Tables 1-6 from Effects of a Caloric Restriction Weight Loss Diet and Exercise on Inflammatory Biomarkers in Overweight/Obese Postmenopausal Women: A Randomized Controlled Trial
Authors: Imayama Ikuyo , Ulrich Cornelia M. , Alfano Catherine M. , Wang Chiachi , Xiao Liren , Wener Mark H. , Campbell Kristin L. , Duggan Catherine , Foster-Schubert Karen E. , Kong Angela , Mason Caitlin E. , Wang Ching-Yun , Blackburn George L. , Bain Carolyn E. , Thompson Henry J. , McTiernan Anne
Published: March 2023

PDF file - 104K, Supplemetary analyses
Supplementary Methods, Figure Legends 1-4 from Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects
Authors: Imai Atsushi , Zeitlin Benjamin D. , Visioli Fernanda , Dong Zhihong , Zhang Zhaocheng , Krishnamurthy Sudha , Light Emily , Worden Frank , Wang Shaomeng , Nör Jacques E.
Published: March 2023

PDF file - 59K
Supplementary Figure 4 from Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects
Authors: Imai Atsushi , Zeitlin Benjamin D. , Visioli Fernanda , Dong Zhihong , Zhang Zhaocheng , Krishnamurthy Sudha , Light Emily , Worden Frank , Wang Shaomeng , Nör Jacques E.
Published: March 2023

PDF fiel - 765K
Supplementary Methods, Tables 1-3, Figure Legends 1-9 from Oncogenicity of the Developmental Transcription Factor Sox9
Authors: Matheu Ander , Collado Manuel , Wise Clare , Manterola Lorea , Cekaite Lina , Tye Angela J. , Canamero Marta , Bujanda Luis , Schedl Andreas , Cheah Kathryn S.E. , Skotheim Rolf I. , Lothe Ragnhild A. , López de Munain Adolfo , Briscoe James , Serrano Manuel , Lovell-Badge Robin
Published: March 2023

PDF file - 3.3MB
Supplementary Methods from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 85K
Supplementary Table 1 from A Multistage Association Study Identifies a Breast Cancer Genetic Locus at NCOA7
Authors: Higginbotham Kathryn S.P. , Breyer Joan P. , Bradley Kevin M. , Schuyler Peggy A. , Plummer W. Dale , Freudenthal Marcia E. , Trentham-Dietz Amy , Newcomb Polly A. , Sanders Melinda E. , Page David L. , Parl Fritz F. , Egan Kathleen M. , Dupont William D. , Smith Jeffrey R.
Published: March 2023

Supplementary Table 1 from A Multistage Association Study Identifies a Breast Cancer Genetic Locus at NCOA7
Supplementary Figure 5 from HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair
Authors: Nowsheen Somaira , Cooper Tiffiny , Bonner James A. , LoBuglio Albert F. , Yang Eddy S.
Published: March 2023

PDF file - 93K, Verification of the expected effects of p65 or IkappaBalpha overexpression on NFkappaB transcriptional activity in breast cancer cells
Supplementary Tables 1-2 from A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
Authors: Laderach Diego J. , Gentilini Lucas D. , Giribaldi Laura , Delgado Victor Cardenas , Nugnes Lorena , Croci Diego O. , Al Nakouzi Nader , Sacca Paula , Casas Gabriel , Mazza Osvaldo , Shipp Margaret A. , Vazquez Elba , Chauchereau Anne , Kutok Jeffery L. , Rodig Scott J. , Elola María T. , Compagno Daniel , Rabinovich Gabriel A.
Published: March 2023

PDF file - 88K, Table S1. Primers used to delineate the 'galectin signature' of prostate cancer cells Table S2. Primers used to determine angiogenesis-related genes
Supplementary Figures 1-2 from A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
Authors: Laderach Diego J. , Gentilini Lucas D. , Giribaldi Laura , Delgado Victor Cardenas , Nugnes Lorena , Croci Diego O. , Al Nakouzi Nader , Sacca Paula , Casas Gabriel , Mazza Osvaldo , Shipp Margaret A. , Vazquez Elba , Chauchereau Anne , Kutok Jeffery L. , Rodig Scott J. , Elola María T. , Compagno Daniel , Rabinovich Gabriel A.
Published: March 2023

PDF file - 123K, Figure S1. Gal-1 mRNA expression and PSA mRNA expression in hormone-responsive (HR) and castration-resistant (CR) LNCaP cells Figure S2: Immunoreactivity of anti-galectin antibodies
Supplementary Methods from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 151K
Supplementary Figure 6 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 422K
Supplementary Figure 4 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 315K
Supplementary Figure 3 from PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
Authors: Brenner J. Chad , Feng Felix Y. , Han Sumin , Patel Sonam , Goyal Siddharth V. , Bou-Maroun Laura M. , Liu Meilan , Lonigro Robert , Prensner John R. , Tomlins Scott A. , Chinnaiyan Arul M.
Published: March 2023

PDF file - 316K
Supplementary Methods, Figures 1-7 from p120RasGAP-Mediated Activation of c-Src Is Critical for Oncogenic Ras to Induce Tumor Invasion
Authors: Chan Po-Chao , Chen Hong-Chen
Published: March 2023

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List of Invited Speakers from Changing the Tumor Microenvironment: New Strategies for Immunotherapy
Authors: Berraondo Pedro , Umansky Viktor , Melero Ignacio
Published: March 2023

PDF file, 72K.
Supplementary Table 4 from Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
Authors: Mitsiades Nicholas , Sung Clifford C. , Schultz Nikolaus , Danila Daniel C. , He Bin , Eedunuri Vijay Kumar , Fleisher Martin , Sander Chris , Sawyers Charles L. , Scher Howard I.
Published: March 2023

XLS file - 91K, Linear correlation matrix resulting from the analysis of the log2-based mRNA levels in primary and metastatic PCas
Supplementary Table 3 from Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
Authors: Mitsiades Nicholas , Sung Clifford C. , Schultz Nikolaus , Danila Daniel C. , He Bin , Eedunuri Vijay Kumar , Fleisher Martin , Sander Chris , Sawyers Charles L. , Scher Howard I.
Published: March 2023

XLS file - 134K, Results from one-way ANOVA comparing average expression of each transcript between groups (normal, primary PrCa and metastatic PrCa)
Supplementary Table 1 from Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
Authors: Mitsiades Nicholas , Sung Clifford C. , Schultz Nikolaus , Danila Daniel C. , He Bin , Eedunuri Vijay Kumar , Fleisher Martin , Sander Chris , Sawyers Charles L. , Scher Howard I.
Published: March 2023

PDF file - 73K, List of studied transcripts for enzymes involved in androgen synthesis and metabolism in prostate cancer
Supplementary Figure Legends 1-5 from Oncolytic Virus and Anti–4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer
Authors: John Liza B. , Howland Linda J. , Flynn Jacqueline K. , West Alison C. , Devaud Christel , Duong Connie P. , Stewart Trina J. , Westwood Jenny A. , Guo Z. Sheng , Bartlett David L. , Smyth Mark J. , Kershaw Michael H. , Darcy Phillip K.
Published: March 2023

PDF file - 94K
Supplementary Figure 3 from Oncolytic Virus and Anti–4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer
Authors: John Liza B. , Howland Linda J. , Flynn Jacqueline K. , West Alison C. , Devaud Christel , Duong Connie P. , Stewart Trina J. , Westwood Jenny A. , Guo Z. Sheng , Bartlett David L. , Smyth Mark J. , Kershaw Michael H. , Darcy Phillip K.
Published: March 2023

PDF file - 182K
Supplementary Video 7 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 1.7MB, Effects of Pi3k Inhibitor LY294002 on Ras-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and LY294002 in 3D
Supplementary Movie 4 from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: March 2023

MOV file - 868K, Supplementary Movie 4. Inhibitory Anti-Beta1 Integrin mAb OS2966 Disrupts BRG3 Adhesion, Spreading, And Migration. Related to Figure 2. Timelapse phase-contrast imaging of BRG3 bevacizumab-resistant cells on fibronectin demonstrates mesenchymal migration of control (10 μg/ml IgG, left) cells into the wound in a scratch wound healing assay. In contrast, BRG3 cells in the treatment condition (10μg/ml OS2966, right) rapidly lose adhesive contacts to the substrate (within 20-30 mins) and are unable to migrate into the wound. Movie images captured with a 40x objective representing approximately 10 hours of imaging, 35 minutes between each frame.
Supplementary Video 3 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 2.1MB, ive cell imaging of H-RASG12V-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in 3D with Dox
Supplementary Video 10 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: March 2023

MOV file - 2.4MB, Effects of mTor Inhibitor rapamycin on Ras-driven luminal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive luminalRas/GFP (MMTV-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and rapamycin in 3D
Supplementary Figures 1 - 8 from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: March 2023

PDF file - 915K, Supplementary Figure 1. Bevacizumab Treatment Promotes Invasiveness Of GBM. Supplementary Figure 2. Increased Expression Of Beta1 In The U87-BEV Cell Line. Supplementary Figure 3. Beta1 Integrin Expression In GBM Associated With Cellular Insults And Mesenchymal Phenotype. Supplementary Figure 4. Establishment And Characterization Of Stable Beta1 Knockdown Clones In The BRG3 Line. Supplementary Figure 5. Beta1 integrin knockdown in resistant GBM cells inhibits mesenchymal phenotype. Supplementary Figure 6. Inhibitory Anti-Beta1 Mab OS2966 Attenuates Adhesion And Proliferation Of BRG Cells. Supplementary Figure 7. A Role For Beta1 In Spheroidal Growth Of U87MG Glioma Cell Line. Supplementary Figure 8. Beta1 Inhibition In Xenograft Models.
Supplementary Legends for Figures 1-3, Table 1 from Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
Authors: Aarntzen Erik H.J.G. , De Vries I. Jolanda M. , Lesterhuis W. Joost , Schuurhuis Danita , Jacobs Joannes F.M. , Bol Kalijn , Schreibelt Gerty , Mus Roel , De Wilt Johannes H.W. , Haanen John B.A.G. , Schadendorf Dirk , Croockewit Alexandra , Blokx Willeke A.M. , Van Rossum Michelle M. , Kwok William W. , Adema Gosse J. , Punt Cornelis J.A. , Figdor Carl G.
Published: March 2023

PDF file - 43K
Supplementary Figure 2 from Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
Authors: Aarntzen Erik H.J.G. , De Vries I. Jolanda M. , Lesterhuis W. Joost , Schuurhuis Danita , Jacobs Joannes F.M. , Bol Kalijn , Schreibelt Gerty , Mus Roel , De Wilt Johannes H.W. , Haanen John B.A.G. , Schadendorf Dirk , Croockewit Alexandra , Blokx Willeke A.M. , Van Rossum Michelle M. , Kwok William W. , Adema Gosse J. , Punt Cornelis J.A. , Figdor Carl G.
Published: March 2023

PDF file - 40K, Vaccine characteristics
Supplementary Figure 1 from Rab25 Is a Tumor Suppressor Gene with Antiangiogenic and Anti-Invasive Activities in Esophageal Squamous Cell Carcinoma
Authors: Tong Man , Chan Kwok Wah , Bao Jessie Y.J. , Wong Kai Yau , Chen Jin-Na , Kwan Pak Shing , Tang Kwan Ho , Fu Li , Qin Yan-Ru , Lok Si , Guan Xin-Yuan , Ma Stephanie
Published: March 2023

PDF file, 2272K, Expression tiling of Rab25 in 6 unpaired ESCC and non-tumor clinical samples.
Supplementary Figure 1 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: March 2023

PDF file - 2.9MB, Targeting strategy for the Trem1 genomic locus and generation of Trem1-deficient mice
Supplementary Figure 3 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: March 2023

PDF - 183K, Measurement of proliferative index and ER � expression in PTENKO tumors treated under different hormonal conditions.
Supplementary Figure 2 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: March 2023

PDF - 188K, Biologic behavior of PTENKO tumors during and after cessation of progesterone therapy.
Supplementary Table 1 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Authors: Cheng Alfred S.L. , Lau Suki S. , Chen Yangchao , Kondo Yutaka , Li May S. , Feng Hai , Ching Arthur K. , Cheung Kin F. , Wong Hoi K. , Tong Joanna H. , Jin Hongchuan , Choy Kwong W. , Yu Jun , To Ka F. , Wong Nathalie , Huang Tim H.-M. , Sung Joseph J.Y.
Published: March 2023

Supplementary Table 1 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Supplementary Figures 1-2, Table 1 from Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity
Authors: Ning Ning , Pan Qin , Zheng Fang , Teitz-Tennenbaum Seagal , Egenti Martin , Yet Ji , Li Mu , Ginestier Christophe , Wicha Max S. , Moyer Jeffrey S. , Prince Mark E.P. , Xu Yingxin , Zhang Xiao-Lian , Huang Shiang , Chang Alfred E. , Li Qiao
Published: March 2023

PDF file - 185K
Supplementary Figure 3 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: March 2023

PDF file, 281K, Prediction of lipid content by MPA. (a) The percentage of lipids that were significantly positively correlated (p-value<0.05) to the MPA lipid-scores (blue) or to the gene expression of ACC (gray). (b) The empirical p-values, denoting the significance of the obtained results, in a minus log10 scale. Similar results were obtained when considering the gene expression levels of FAS and ACL (Supplementary Table 3).