bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep Brain Stimulation, Authenticity and Value
Authors: PUGH JONATHAN , MASLEN HANNAH , SAVULESCU JULIAN
Published: September 2017

Deep brain stimulation has been of considerable interest to bioethicists, in large part because of the effects that the intervention can occasionally have on central features of the recipient’s personality. These effects raise questions regarding the philosophical concept of authenticity. In this article, we expand on our earlier work on the concept of authenticity in the context of deep brain stimulation by developing a diachronic, value-based account of authenticity. Our account draws on both existentialist and essentialist approaches to authenticity, and Laura Waddell Ekstrom’s coherentist approach to personal autonomy. In developing our account, we respond to Sven Nyholm and Elizabeth O’Neill’s synchronic approach to authenticity, and explain how the diachronic approach we defend can have practical utility, contrary to Alexandre Erler and Tony Hope’s criticism of autonomy-based approaches to authenticity. Having drawn a distinction between the authenticity of an individual’s traits and the authenticity of that person’s values, we consider how our conception of authenticity applies to the context of anorexia nervosa in comparison to other prominent accounts of authenticity. We conclude with some reflections on the prudential value of authenticity, and by highlighting how the language of authenticity can be invoked to justify covert forms of paternalism that run contrary to the value of individuality that seems to be at the heart of authenticity.
A Probit Latent State IRT Model With Latent Item-Effect	Variables
Authors: Thielemann Désirée , Sengewald Marie-Ann , Kappler Gregor , Steyer Rolf
Published: September 2017

Abstract. We present a probit latent state model for dichotomous items with one latent state variable for each occasion of measurement and one latent item-effect variable for each item, except for a reference item. All latent variables are well defined in terms of conditional probabilities. The model offers the possibility to include explanatory variables for the latent states as well as for the latent item-effect variables. We illustrate the model by a data example with the life satisfaction scale of the Freiburg Personality Inventory (FPI-R; Fahrenberg, Hampel, & Selg, 1984 ) assessed at three time points. Allowing for item-effect variables improves model fit considerably and enhances our knowledge about the items. In some applications, this model opens new ways to investigate differential item functioning, and in others it allows to study response styles.
On the Definition of Latent-State-Trait Models With Autoregressive	Effects
Authors: Eid Michael , Holtmann Jana , Santangelo Philip , Ebner-Priemer Ulrich
Published: September 2017

Abstract. In longitudinal studies with short time lags, classical models of latent state-trait (LST) theory that assume no carry-over effects between neighboring occasions of measurement are often inappropriate, and have to be extended by including autoregressive effects. The way in which autoregressive effects should be defined in LST models is still an open question. In a recently published revision of LST theory (LST-R theory), Steyer, Mayer, Geiser, and Cole (2015) stated that the trait-state-occasion (TSO) model ( Cole, Martin, & Steiger, 2005 ), one of the most widely applied LST models with autoregressive effects, is not an LST-R model, implying that proponents of LST-R theory might recommend not to apply the TSO model. In the present article, we show that a version of the TSO model can be defined on the basis of LST-R theory and that some of its restrictions can be reasonably relaxed. Our model is based on the idea that situational effects can change time-specific dispositions, and it makes full use of the basic idea of LST-R theory that dispositions to react to situational influences are dynamic and malleable. The latent variables of the model have a clear meaning that is explained in detail.
Safety Management Practices Hindering the Development of Safety Performance Indicators in Aviation Service Providers
Authors: Ioannou Crystal , Harris Don , Dahlstrom Nicklas
Published: September 2017

Abstract. Five aviation service providers participated in a study aiming to identify factors that impact the implementation of a safety management system and the safety performance of the organization. Safety managers were interviewed and their comments analyzed using grounded theory approach. Hindering factors were categorized and integrated into a model.
High somatic mutation and neoantigen burden are correlated with decreased progression-free survival in multiple myeloma
Authors: Miller A , Asmann Y , Cattaneo L , Braggio E , Keats J , Auclair D , Lonial S ,   The MMRF CoMMpass Network, Russell S J , Stewart A K
Published: September 2017

Tumor-specific mutations can result in immunogenic neoantigens, both of which have been correlated with responsiveness to immune checkpoint inhibitors in highly mutagenic cancers. However, early results of single-agent checkpoint inhibitors in multiple myeloma (MM) have been underwhelming. Therefore, we sought to understand the relationship between mutation and neoantigen landscape of MM patients and responsiveness to therapies. Somatic mutation burden, neoantigen load, and response to therapy were determined using interim data from the MMRF CoMMpass study (NCT01454297) on 664 MM patients. In this population, the mean somatic and missense mutation loads were 405.84(s=608.55) and 63.90(s=95.88) mutations per patient, respectively. There was a positive linear relationship between mutation and neoantigen burdens (R2=0.862). The average predicted neoantigen load was 23.52(s=52.14) neoantigens with an average of 9.40(s=26.97) expressed neoantigens. Survival analysis revealed significantly shorter progression-free survival (PFS) in patients with greater than average somatic missense mutation load (N=163, 0.493 vs 0.726 2-year PFS, P=0.0023) and predicted expressed neoantigen load (N=214, 0.555 vs 0.729 2-year PFS, P=0.0028). This pattern is maintained when stratified by disease stage and cytogenetic abnormalities. Therefore, high mutation and neoantigen load are clinically relevant risk factors that negatively impact survival of MM patients under current standards of care.
High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
Authors: Burlacu Elena , Lackmann Fredrik , Aguilar Lisbeth-Carolina , Belikov Sergey , Nues Rob van , Trahan Christian , Hector Ralph D. , Dominelli-Whiteley Nicholas , Cockroft Scott L. , Wieslander Lars , Oeffinger Marlene , Granneman Sander
Published: September 2017

While the protein composition of various yeast 60S ribosomal subunit assembly intermediates has been studied in detail, little is known about ribosomal RNA (rRNA) structural rearrangements that take place during early 60S assembly steps. Using a high-throughput RNA structure probing method, we provide nucleotide resolution insights into rRNA structural rearrangements during nucleolar 60S assembly. Our results suggest that many rRNA-folding steps, such as folding of 5.8S rRNA, occur at a very specific stage of assembly, and propose that downstream nuclear assembly events can only continue once 5.8S folding has been completed. Our maps of nucleotide flexibility enable making predictions about the establishment of protein–rRNA interactions, providing intriguing insights into the temporal order of protein–rRNA as well as long-range inter-domain rRNA interactions. These data argue that many distant domains in the rRNA can assemble simultaneously during early 60S assembly and underscore the enormous complexity of 60S synthesis.
Establishing and storing of deterministic quantum entanglement among three distant atomic ensembles
Authors: Yan Zhihui , Wu Liang , Jia Xiaojun , Liu Yanhong , Deng Ruijie , Li Shujing , Wang Hai , Xie Changde , Peng Kunchi
Published: September 2017

It is crucial for the physical realization of quantum information networks to first establish entanglement among multiple space-separated quantum memories and then, at a user-controlled moment, to transfer the stored entanglement to quantum channels for distribution and conveyance of information. Here we present an experimental demonstration on generation, storage, and transfer of deterministic quantum entanglement among three spatially separated atomic ensembles. The off-line prepared multipartite entanglement of optical modes is mapped into three distant atomic ensembles to establish entanglement of atomic spin waves via electromagnetically induced transparency light–matter interaction. Then the stored atomic entanglement is transferred into a tripartite quadrature entangled state of light, which is space-separated and can be dynamically allocated to three quantum channels for conveying quantum information. The existence of entanglement among three released optical modes verifies that the system has the capacity to preserve multipartite entanglement. The presented protocol can be directly extended to larger quantum networks with more nodes.
Springtime winds drive Ross Sea ice variability and change in the following autumn
Authors: Holland Marika M. , Landrum Laura , Raphael Marilyn , Stammerjohn Sharon
Published: September 2017

Autumn sea ice trends in the western Ross Sea dominate increases in Antarctic sea ice and are outside the range simulated by climate models. Here we use a number of independent data sets to show that variability in western Ross Sea autumn ice conditions is largely driven by springtime zonal winds in the high latitude South Pacific, with a lead-time of 5 months. Enhanced zonal winds dynamically thin the ice, allowing an earlier melt out, enhanced solar absorption, and reduced ice cover the next autumn. This seasonal lag relationship has implications for sea ice prediction. Given a weakening trend in springtime zonal winds, this lagged relationship can also explain an important fraction of the observed sea ice increase. An analysis of climate models indicates that they simulate weaker relationships and wind trends than observed. This contributes to weak western Ross Sea ice trends in climate model simulations.
Large three-dimensional photonic crystals based on monocrystalline liquid crystal blue phases
Authors: Chen Chun-Wei , Hou Chien-Tsung , Li Cheng-Chang , Jau Hung-Chang , Wang Chun-Ta , Hong Ching-Lang , Guo Duan-Yi , Wang Cheng-Yu , Chiang Sheng-Ping , Bunning Timothy J. , Khoo Iam-Choon , Lin Tsung-Hsien
Published: September 2017

Although there have been intense efforts to fabricate large three-dimensional photonic crystals in order to realize their full potential, the technologies developed so far are still beset with various material processing and cost issues. Conventional top-down fabrications are costly and time-consuming, whereas natural self-assembly and bottom-up fabrications often result in high defect density and limited dimensions. Here we report the fabrication of extraordinarily large monocrystalline photonic crystals by controlling the self-assembly processes which occur in unique phases of liquid crystals that exhibit three-dimensional photonic-crystalline properties called liquid-crystal blue phases. In particular, we have developed a gradient-temperature technique that enables three-dimensional photonic crystals to grow to lateral dimensions of ~1 cm (~30,000 of unit cells) and thickness of ~100 μm (~ 300 unit cells). These giant single crystals exhibit extraordinarily sharp photonic bandgaps with high reflectivity, long-range periodicity in all dimensions and well-defined lattice orientation.
IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
Authors: Dambuza Ivy M. , He Chang , Choi Jin Kyeong , Yu Cheng-Rong , Wang Renxi , Mattapallil Mary J. , Wingfield Paul T. , Caspi Rachel R. , Egwuagu Charles E.
Published: September 2017

Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 subunits. IL-35 suppresses autoimmune diseases while preventing host defense to infection and promoting tumor growth and metastasis by converting resting B and T cells into IL-10-producing and IL-35-producing regulatory B (Breg) and T (Treg) cells. Despite sharing the IL-12p35 subunit, IL-12 (IL-12p35/IL-12p40) promotes inflammatory responses whereas IL-35 (IL-12p35/Ebi3) induces regulatory responses, suggesting that IL-12p35 may have unknown intrinsic immune-regulatory functions regulated by its heterodimeric partner. Here we show that the IL-12p35 subunit has immunoregulatory functions hitherto attributed to IL-35. IL-12p35 suppresses lymphocyte proliferation, induces expansion of IL-10-expressing and IL-35-expressing B cells and ameliorates autoimmune uveitis in mice by antagonizing pathogenic Th17 responses. Recapitulation of essential immunosuppressive activities of IL-35 indicates that IL-12p35 may be utilized for in vivo expansion of Breg cells and autologous Breg cell immunotherapy. Furthermore, our uveitis data suggest that intrinsic immunoregulatory activities of other single chain IL-12 subunits might be exploited to treat other autoimmune diseases.
Continual reproduction of self-assembling oligotriazole peptide nanomaterials
Authors: Brea Roberto J. , Devaraj Neal K.
Published: September 2017

Autocatalytic chemical reactions, whereby a molecule is able to catalyze its own formation from a set of precursors, mimic nature’s ability to generate identical copies of relevant biomolecules, and are thought to have been crucial for the origin of life. While several molecular autocatalysts have been previously reported, coupling autocatalytic behavior to macromolecular self-assembly has been challenging. Here, we report a non-enzymatic and chemoselective methodology capable of autocatalytically producing triskelion peptides that self-associate into spherical bioinspired nanostructures. Serial transfer experiments demonstrate that oligotriazole autocatalysis successfully leads to continual self-assembly of three-dimensional nanospheres. Triskelion-based spherical architectures offer an opportunity to organize biomolecules and chemical reactions in unique, nanoscale compartments. The use of peptide-based autocatalysts that are capable of self-assembly represents a promising method for the development of self-synthesizing biomaterials, and may shed light on understanding life’s chemical origins.
A coordination polymer for the site-specific integration of semiconducting sequences into DNA-based materials
Authors: Al-Mahamad Lamia L. G. , El-Zubir Osama , Smith David G. , Horrocks Benjamin R. , Houlton Andrew
Published: September 2017

Advances in bottom-up material design have been significantly progressed through DNA-based approaches. However, the routine integration of semiconducting properties, particularly long-range electrical conduction, into the basic topological motif of DNA remains challenging. Here, we demonstrate this with a coordination polymer derived from 6-thioguanosine (6-TG-H), a sulfur-containing analog of a natural nucleoside. The complexation reaction with Au(I) ions spontaneously assembles luminescent one-dimensional helical chains, characterized as {AuI(μ-6-TG)}n, extending many μm in length that are structurally analogous to natural DNA. Uniquely, for such a material, this gold-thiolate can be transformed into a wire-like conducting form by oxidative doping. We also show that this self-assembly reaction is compatible with a 6-TG-modified DNA duplex and provides a straightforward method by which to integrate semiconducting sequences, site-specifically, into the framework of DNA materials, transforming their properties in a fundamental and technologically useful manner.
Atomistic computer simulations of water interactions and dissolution of inorganic glasses
Authors: Du Jincheng , Rimsza Jessica M.
Published: September 2017

Computer simulations at the atomistic scale play an increasing important role in understanding the structure features, and the structure–property relationships of glass and amorphous materials. In this paper, we reviewed atomistic simulation methods ranging from first principles calculations and ab initio molecular dynamics (AIMD) simulations, to classical molecular dynamics (MD), and meso-scale kinetic Monte Carlo (KMC) simulations and their applications to study the reactions and interactions of inorganic glasses with water and the dissolution behaviors of ﻿inorganic glasses. Particularly, the use of these simulation methods in understanding the reaction mechanisms of water with oxide glasses, water–glass interfaces, hydrated porous silica gels formation, the structure and properties of multicomponent glasses, and microstructure evolution are reviewed. The advantages and disadvantageous of these simulation methods are discussed and the current challenges and future direction of atomistic simulations in glass dissolution presented.
Onset of static and dynamic universality among molecular models of polymers
Authors: Takahashi Kazuaki Z. , Nishimura Ryuto , Yamato Nobuyoshi , Yasuoka Kenji , Masubuchi Yuichi
Published: September 2017

A quantitatively accurate prediction of properties for entangled polymers is a long-standing challenge that must be addressed to enable efficient development of these materials. The complex nature of polymers is the fundamental origin of this challenge. Specifically, the chemistry, structure, and dynamics at the atomistic scale affect properties at the meso and macro scales. Therefore, quantitative predictions must start from atomistic molecular dynamics (AMD) simulations. Combined use of atomistic and coarse-grained (CG) models is a promising approach to estimate long-timescale behavior of entangled polymers. However, a systematic coarse-graining is still to be done for bridging the gap of length and time scales while retaining atomistic characteristics. Here we examine the gaps among models, using a generic mapping scheme based on power laws that are closely related to universality in polymer structure and dynamics. The scheme reveals the characteristic length and time for the onset of universality between the vastly different scales of an atomistic model of polyethylene and the bead-spring Kremer–Grest (KG) model. The mapping between CG model of polystyrene and the KG model demonstrates the fast onset of universality, and polymer dynamics up to the subsecond time scale are observed. Thus, quantitatively traceable timescales of polymer MD simulations can be significantly increased.
Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters
Authors: Usuki Fusako , Fujimura Masatake , Yamashita Akio
Published: September 2017

Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning results in the upregulation of membrane transporters, leading to a decrease in intracellular mercury content. Our analyses showed that ER stress preconditioning upregulated the expression of methionine transporters that affect the cellular influx of MeHg, LAT1, LAT3, and SNAT2; and a membrane transporter that affects the efflux of MeHg, ABCC4, in MeHg-susceptible myogenic cells. Among these, ABCC4 transporter expression exhibited the greatest elevation. The functional significance of ABCC4 transporter in the efflux of MeHg was shown by the ABCC4 inhibition study. Additionally, we identified the role of phospho-eIF2α/ATF4 pathway in the upregulation of LAT1, SNAT2, and ABCC4 and the role of NMD suppression in LAT3 upregulation. Further, we detected that ER stress preconditioning amplified membrane transporter expression most likely through the translation of the upregulated mRNAs caused by ATF4-dependent transcription and NMD suppression. Taken together, these results suggested that the phospho-eIF2α/ATF4 pathway activation and NMD suppression may represent therapeutic targets for the alleviation of MeHg cytotoxicity by enhancing mercury efflux besides inducing protective stress responses.
Direct exciton emission from atomically thin transition metal dichalcogenide heterostructures near the lifetime limit
Authors: Wierzbowski Jakob , Klein Julian , Sigger Florian , Straubinger Christian , Kremser Malte , Taniguchi Takashi , Watanabe Kenji , Wurstbauer Ursula , Holleitner Alexander W. , Kaniber Michael , Müller Kai , Finley Jonathan J.
Published: September 2017

We demonstrate the reduction of the inhomogeneous linewidth of the free excitons in atomically thin transition metal dichalcogenides (TMDCs) MoSe2, WSe2 and MoS2 by encapsulation within few nanometre thick hBN. Encapsulation is shown to result in a significant reduction of the 10 K excitonic linewidths down to ∼3.5 meV for n-MoSe2, ∼5.0  meV for p-WSe2 and ∼4.8 meV for n-MoS2. Evidence is obtained that the hBN environment effectively lowers the Fermi level since the relative spectral weight shifts towards the neutral exciton emission in n-doped TMDCs and towards charged exciton emission in p-doped TMDCs. Moreover, we find that fully encapsulated MoS2 shows resolvable exciton and trion emission even after high power density excitation in contrast to non-encapsulated materials. Our findings suggest that encapsulation of mechanically exfoliated few-monolayer TMDCs within nanometre thick hBN dramatically enhances optical quality, producing ultra-narrow linewidths that approach the homogeneous limit.
Up-regulation of chemokine receptor CCR4 is associated with Human Hepatocellular Carcinoma malignant behavior
Authors: Cheng Xi , Wu Huo , Jin Zhi-Jian , Ma Ding , Yuen Stanley , Jing Xiao-Qian , Shi Min-Min , Shen Bai-Yong , Peng Cheng-Hong , Zhao Ren , Qiu Wei-Hua
Published: September 2017

Studies indicate that the chemokine receptor is responsible for poor prognosis of hepatocellular carcinoma (HCC) patients. In this study, we initially demonstrated that CCR4 is overexpressed in HCC specimens, and its elevation in HCC tissues positively correlates with tumor capsule breakthrough and vascular invasion. Although overexpression of CCR4 failed to influent proliferation of HCC cells in vitro apparently, the prominent acceleration on HCC tumor growth in vivo was remarkable. The underlying mechanism may be involved in neovascularization. Interestingly, different from effect on proliferation, CCR4 overexpression could trigger HCC metastasis both in vitro and in vivo also induced HCC cell epithelial-mesenchymal transition (EMT) as well. Then we identified matrix metalloproteinase 2 (MMP2) as a direct target of CCR4 which plays an important role in CCR4-mediated HCC cell invasion, which was up-regulated by ERK/AKT signaling. Positive correlation between CCR4 and MMP2 expression was also observed in HCC tissues. In conclusion, our study suggested that chemokine receptor CCR4 promotes HCC malignancy and facilitated HCC cell metastases via ERK/AKT/MMP2 pathway. These findings suggest that CCR4 may be a potential new diagnostic and prognostic marker in HCC, and targeting CCR4 may be a potential therapeutic option for blocking HCC metastasis.
CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma
Authors: Hoe Susan Ling Ling , Tan Lu Ping , Abdul Aziz Norazlin , Liew Kitson , Teow Sin-Yeang , Abdul Razak Fazlyn Reeny , Chin Yoon Ming , Mohamed Shahrehan Nurul Ashikin , Chu Tai Lin , Mohd Kornain Noor Kaslina , Peh Suat-Cheng , Koay Cheng Eng , Lo Kwok-Wai , Ahmad Munirah , Ng Ching-Ching , Khoo Alan Soo-Beng
Published: September 2017

Subpopulations of nasopharyngeal carcinoma (NPC) contain cells with differential tumourigenic properties. Our study evaluates the tumourigenic potential of CD24, CD44, EpCAM and combination of EpCAM/CD44 cells in NPC. CD44br and EpCAMbr cells enriched for higher S-phase cell content, faster-growing tumourigenic cells leading to tumours with larger volume and higher mitotic figures. Although CD44br and EpCAMbr cells significantly enriched for tumour-initiating cells (TICs), all cells could retain self-renewal property for at least four generations. Compared to CD44 marker alone, EpCAM/CD44dbr marker did not enhance for cells with faster-growing ability or higher TIC frequency. Cells expressing high CD44 or EpCAM had lower KLF4 and p21 in NPC subpopulations. KLF4-overexpressed EpCAMbr cells had slower growth while Kenpaullone inhibition of KLF4 transcription increased in vitro cell proliferation. Compared to non-NPC, NPC specimens had increased expression of EPCAM, of which tumours from advanced stage of NPC had higher expression. Together, our study provides evidence that EpCAM is a potentially important marker in NPC.
Curved optical solitons subject to transverse acceleration in reorientational soft matter
Authors: Laudyn Urszula A. , Kwaśny Michał , Sala Filip A. , Karpierz Mirosław A. , Smyth Noel F. , Assanto Gaetano
Published: September 2017

We demonstrate that optical spatial solitons with non-rectilinear trajectories can be made to propagate in a uniaxial dielectric with a transversely modulated orientation of the optic axis. Exploiting the reorientational nonlinearity of nematic liquid crystals and imposing a linear variation of the background alignment of the molecular director, we observe solitons whose trajectories have either a monotonic or a non-monotonic curvature in the observation plane of propagation, depending on either the synergistic or counteracting roles of wavefront distortion and birefringent walk-off, respectively. The observed effect is well modelled in the weakly nonlinear regime using momentum conservation of the self-collimated beams in the presence of the spatial nonlocality of the medium response. Since reorientational solitons can act as passive waveguides for other weak optical signals, these results introduce a wealth of possibilities for all-optical signal routing and light-induced photonic interconnects.
Aluminium matrix tungsten aluminide and tungsten reinforced composites by solid-state diffusion mechanism
Authors: Zhang Hanzhu , Feng Peizhong , Akhtar Farid
Published: September 2017

In-situ processing of tungsten aluminide and tungsten reinforced aluminium matrix composites from elemental tungsten (W) and aluminium (Al) was investigated by thermal analysis and pulsed current processing (PCP). The formation mechanism of tungsten aluminides in 80 at.% Al-20 at.% W system was controlled by atomic diffusion. The particle size of W and Al in the starting powder mixture regulated the phase formation and microstructure. PCP of micron sized elemental Al and W resulted in formation of particulate reinforcements, W, Al4W and Al12W, dispersed in Al matrix. W particles were surrounded by a ~3 μm thick dual-layer structure of Al12W and Al4W. The hardness of Al matrix, containing Al12W reinforcements, was increased by 50% compared to pure Al, from 0.3 GPa to 0.45 GPa and W reinforcements showed a hardness of 4.35 GPa. On PCP of 80 at.% Al-20 at.% W mixture with particle size of W and Al ~70 nm, resulted in formation of Al4W as major phase along with small fractions of Al5W and unreacted W phase. This suggested strongly that the particle size of the starting elemental Al and W could be the controlling parameter in processing and tailoring of phase evolution, microstructure of particulate reinforced Al matrix composite.
Erratum: The impact of host sex on the outcome of co-infection
Authors: Thompson Olivia , Gipson Stephen A. Y. , Hall Matthew D.
Published: September 2017

A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
Interspecific behavioural synchronization: dogs exhibit locomotor synchrony with humans
Authors: Duranton Charlotte , Bedossa Thierry , Gaunet Florence
Published: September 2017

Behavioural synchronization is widespread among living beings, including humans. Pairs of humans synchronize their behaviour in various situations, such as walking together. Affiliation between dyadic partners is known to promote behavioral synchronization. Surprisingly, however, interspecific synchronization has recived little scientific investigation. Dogs are sensitive to human cues, and share strong affiliative bonds with their owners. We thus investigated whether, when allowed to move freely in an enclosed unfamiliar space, dogs synchronize their behaviour with that of their owners’. We found that dogs visibly synchronized their location with their owner (staying in close proximity and moving to the same area), as well as their activity and temporal changes in activity (moving when their owner moved, standing still when their owner stood still, and gazing in the same direction as their owner). The present study demonstrates that owners act as attractors for their dogs in an indoor space, as mothers do for their children.
In situ solid-state fabrication of hybrid AgCl/AgI/AgIO3 with improved UV-to-visible photocatalytic performance
Authors: Xie Jing , Cao Yali , Jia Dianzeng , Li Yizhao , Wang Kun , Xu Hui
Published: September 2017

The AgCl/AgI/AgIO3 composites were synthesized through a one-pot room-temperature in situ solid-state approach with the feature of convenient and eco-friendly. The as-prepared composites exhibit superior photocatalytic performance than pure AgIO3 for the degradation of methyl orange (MO) under both UV and visible light irradiation. The photodegradation rate toward MO of the AgCl/AgI/AgIO3 photocatalyst can reach 100% after 12 min irradiation under UV light, or 85.4% after 50 min irradiation under visible light, being significantly higher than AgCl, AgI, AgIO3 and AgI/AgIO3. In addition, the AgCl/AgI/AgIO3 photocatalyst possesses strong photooxidation ability for the degradation of rhodamine B (RhB), methylene blue (MB), phenol, bisphenol A (BPA) and tetracycline hydrochloride under visible light irradiation. The reactive species capture experiments confirmed that the h+ and •O2− play an essential role during the photocatalytic process under UV light or visible light irradiation. The enhanced effect may be beneficial from the enhanced light adsorption in full spectrum and increased separation efficiency of photogenerated hole-electron pairs, which can be ascribed to the synergistic effect among AgCl, AgI and AgIO3 nanoplates in AgCl/AgI/AgIO3 composites.
Liquid Marble as Bioreactor for Engineering Three-Dimensional Toroid Tissues
Authors: Vadivelu Raja K. , Kamble Harshad , Munaz Ahmed , Nguyen Nam-Trung
Published: September 2017

Liquid marble is a liquid droplet coated with hydrophobic powder that can be used as a bioreactor. This paper reports the three-dimensional self-assembly and culture of a cell toroid in a slow-releasing, non-adhesive and evaporation-reducing bioreactor platform based on a liquid marble. The bioreactor is constructed by embedding a hydrogel sphere containing growth factor into a liquid marble filled with a suspension of dissociated cells. The hydrogel maintains the water content and concurrently acts as a slow-release carrier. The concentration gradient of growth factor induces cell migration and assembly into toroidal aggregates. An optimum cell concentration resulted in the toroidal (doughnut-like) tissue after 12 hours. The harvested cell toroids showed rapid closure of the inner opening when treated with the growth factor. We also present a geometric growth model to describe the shape of the toroidal tissue over time. In analogy to the classical two-dimensional scratch assay, we propose that the cell toroids reported here open up new possibilities to screen drugs affecting cell migration in three dimensions.
Headspace-gas chromatography-mass spectrometry for the rapid determination of possible biomarkers in urine samples
Authors: González Paredes Rosa María , García Pinto Carmelo , Pérez Pavón José Luis , Moreno Cordero Bernardo
Published: September 2017

The development of rapid analytical strategies plays a vital role for the research, discovery and confirmation of analytes that can be sensitive biomarkers.
The electronic structure of Ag1−xSn1+xSe2 (x = 0.0, 0.1, 0.2, 0.25 and 1.0)
Authors: Wakita Takanori , Paris Eugenio , Kobayashi Kaya , Terashima Kensei , Hacisalihoǧlu Muammer Yasin , Ueno Teppei , Bondino Federica , Magnano Elena , Píš Igor , Olivi Luca , Akimitsu Jun , Muraoka Yuji , Yokoya Takayoshi , Saini Naurang L.
Published: September 2017

Distinct valence electronic structures of SnSe and Ag1−xSn1+xSe2 are revealed by a combined analysis of X-ray absorption and X-ray photoemission spectroscopies.
Near-infrared light and pH-responsive Au@carbon/calcium phosphate nanoparticles for imaging and chemo-photothermal cancer therapy of cancer cells
Authors: Wang Huiyuan , Zhang Manjie , Zhang Lingyu , Li Shengnan , Li Lu , Li Xiliang , Yu Min , Mou Zhongcheng , Wang Tingting , Wang Chungang , Su Zhongmin
Published: September 2017

A novel Au@carbon/calcium phosphate core–shell nanoparticles were synthesized for CT imaging and chemo-photothermal cancer therapy in vitro.
The Cu(i)-catalysed Huisgen 1,3-dipolar cycloaddition route to (bio-)organic functionalisation of polyoxovanadates
Authors: Linnenberg Oliver , Kondinski Aleksandar , Stöcker Cornelia , Monakhov Kirill Yu.
Published: September 2017

We elaborated a synthetic protocol that provides convenient access to a “click”-directed covalent conjugation between 51V-NMR detectable, redox-active polyoxo(alkoxo)vanadate and (bio-)organoazides. The compounds can potentially be used in bioelectronics, biocatalysis and biosensorics.
Evaluating particle-suspension reactor designs for Z-scheme solar water splittingviatransport and kinetic modeling
Authors: Bala Chandran Rohini , Breen Sasuke , Shao Yuanxun , Ardo Shane , Weber Adam Z.
Published: September 2017

Simulations of coupled light absorption, transport and kinetics processes in a tandem, vertically-stacked particle-suspension reactor design for solar-water splitting.
Figure of merit ZT of a thermoelectric device defined from materials properties
Authors: Snyder G. Jeffrey , Snyder Alemayouh H.
Published: September 2017

The thermoelectric device ZT is calculated using a simple spreadsheet calculator.
Comparative suppressing effects of black and green teas on the formation of advanced glycation end products (AGEs) and AGE-induced oxidative stress
Authors: Ramlagan P. , Rondeau P. , Planesse C. , Neergheen-Bhujun V. S. , Bourdon E. , Bahorun T.
Published: September 2017

The anti-diabetic potential of black and green teasviathe inhibition of carbohydrate hydrolysing enzymatic activities, suppression of glycation and reduction in AGE-induced oxidative stress.
Ultrasensitive detection of trace amounts of lead in water by LIBS-LIF using a wood-slice substrate as a water absorber
Authors: Kang Juan , Li Runhua , Wang Yarui , Chen Yuqi , Yang Yuxiang
Published: September 2017

LIBS-LIF combined with a convenient sample-pretreatment method was used to analyze trace amounts of lead in water with ultra-high sensitivity.
Deterministic droplet-based co-encapsulation and pairing of microparticles via active sorting and downstream merging
Authors: Chung Meng Ting , Núñez Daniel , Cai Dawen , Kurabayashi Katsuo
Published: September 2017

A microfluidic platform integrates droplet sorting and merging functions for efficient and deterministic pairing of two distinct particles inside droplets.
Self-assembled composite microparticles with surface protrudent porphyrin nanoparticles enhance cellular uptake and photodynamic therapy
Authors: Zhang Wenbo , Li Huiying , Qin Ying , Gao Changyou
Published: September 2017

Microparticles with surface protrudent porphyrins enhance cell internalization, producing massive intracellular ROS and thereby leading to efficient photodynamic cell death.
Photo-induced interfacial electron transfer of ZnO nanocrystals to control supramolecular assembly in water
Authors: Cieślak Anna M. , Janeček Emma-Rose , Sokołowski Kamil , Ratajczyk Tomasz , Leszczyński Michał K. , Scherman Oren A. , Lewiński Janusz
Published: September 2017

The light-induced redox properties of semiconducting nanocrystals can be utilized for reversible modulation of non-photoresponsive interfacial supramolecular systems.
One-step functionalization of magnetic nanoparticles with 4-mercaptophenylboronic acid for a highly efficient analysis of N-glycopeptides
Authors: Yao Jizong , Wang Jiawen , Sun Nianrong , Deng Chunhui
Published: September 2017

A very simple and amazing approach was proposed to synthesize MPBA functionalized magnetic nanoparticles via the interaction between Fe and SH, and the as-prepared nanoparticles were successfully applied for the efficient analysis of glycopeptides in complex bio-samples with sensitivity and selectivity.
High thermoelectric performances of monolayer SnSe allotropes
Authors: Hu Zi-Yu , Li Kai-Yue , Lu Yong , Huang Yan , Shao Xiao-Hong
Published: September 2017

β-SnSe is one of the most promising thermoelectric materials with low thermal conductivity and a high power.
Thermal and electronic transport characteristics of highly stretchable graphene kirigami
Authors: Mortazavi Bohayra , Lherbier Aurélien , Fan Zheyong , Harju Ari , Rabczuk Timon , Charlier Jean-Christophe
Published: September 2017

A numerical study of the thermal and electronic transport characteristics and of the high stretchability of graphene kirigami structures.
Enhanced efficiency and air-stability of NiOX-based perovskite solar cells via PCBM electron transport layer modification with Triton X-100
Authors: Lee Kisu , Ryu Jaehoon , Yu Haejun , Yun Juyoung , Lee Jungsup , Jang Jyongsik
Published: September 2017

In this work, a phenyl-C61-butyric acid methyl ester (PCBM) electron transport layer was modified with Triton X-100, and this improved the photovoltaic performance and air-stability of perovskite solar cells.
Plasmon mediated Fe–O in an octahedral site of cuprospinel by Cu NPs for photocatalytic hydrogen evolution
Authors: Wang An , Yang Hewei , Song Ting , Sun Quan , Liu Hui , Wang Tingting , Zeng Heping
Published: September 2017

The LSPR of Cu NPs synthesized on CuFe2O4 enhanced the vibration of Fe–O as an active site to facilitate the HER process.
Hydrogels through emulsion templating: sequential polymerization and double networks
Authors: Kovačič Sebastijan , Silverstein Michael S.
Published: September 2017

Robust, high-porosity, emulsion-templated double-network hydrogels: the polymerization sequence and the polyelectrolyte and neutral-polymer contents determine the structures and the properties.
Surface and interface engineering of CoNi layered double hydroxides for efficient methanol oxidation reaction
Authors: Luo Shuli , Qian Lei , Liao Menglong , Hu Xiaorong , Xiao Dan
Published: September 2017

Surface and interface engineering (P doping and coupling with rGO) were adopted to enhance the MOR activity of CoNi LDHs.
Three-dimensional graphene networks and reduced graphene oxide nanosheets co-modified dye-sensitized solar cells
Authors: Tang Bo , Ji Guojian , Wang Zhengwei , Chen Haiqun , Li Xufei , Yu Haogang , Li Sen , Liu Hong
Published: September 2017

Graphene assisted dye-sensitized solar cells (DSSCs) have drawn increasing attention because of their high performances.
Separation of rare-earth ions from ethylene glycol (+LiCl) solutions by non-aqueous solvent extraction with Cyanex 923
Authors: Batchu Nagaphani Kumar , Vander Hoogerstraete Tom , Banerjee Dipanjan , Binnemans Koen
Published: September 2017

Mixtures of rare earths are separation by non-aqueous solvent extraction with two immiscible organic phases.
Pseudo three-component approach to coumarin-annulated azepines: synthesis of coumarin[3,4-b]azepines
Authors: Manjappa Kiran B. , Peng Yu-Ting , Liou Teau-Jiuan , Yang Ding-Yah
Published: September 2017

A series of coumarin-annulated azepines were synthesized via acid-catalyzed condensation of 3-amino-4-hydroxycoumarin with two equivalents of substituted acetophenones in toluene with moderate to good yields.
Correction: A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3+ and Al3+ in living cells and a near-perfect aqueous solution
Authors: Jo Tae Geun , Jung Jae Min , Han Jiyeon , Lim Mi Hee , Kim Cheal
Published: September 2017

Correction for ‘A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3+ and Al3+ in living cells and a near-perfect aqueous solution’ by Tae Geun Jo et al., RSC Adv., 2017, 7, 28723–28732.
Bright and sensitive ratiometric fluorescent probe enabling endogenous FA imaging and mechanistic exploration of indirect oxidative damage due to FA in various living systems
Authors: Dou Kun , Chen Guang , Yu Fabiao , Liu Yuxia , Chen Lingxin , Cao Ziping , Chen Tao , Li Yulin , You Jinmao
Published: September 2017

Herein, we present the design and multi-application of a bright and sensitive ratiometric fluorescent probe,PIPBA, for the imaging of formaldehyde (FA) in living systems.
Selective electrochemical CO2 reduction over highly porous gold films
Authors: Chen Chengzhen , Zhang Bo , Zhong Juhua , Cheng Zhenmin
Published: September 2017

Electrocatalytic reduction of CO2 to CO is usually subject to the competitive reduction of H+ to hydrogen.
Simple transfer from spin coating to blade coating through processing aggregated solutions
Authors: Hernandez Jeff L. , Deb Nabankur , Wolfe Rylan M. W. , Lo Chi Kin , Engmann Sebastian , Richter Lee J. , Reynolds John R.
Published: September 2017

We observe that thin film solar cells based on poly[5-(2-hexyldecyl)-1,3-thieno[3,4-c]pyrrole-4,6-dione-alt-5,5-(2,5-bis(3-dodecylthiophen-2-yl)-thiophene)] [P(T3-TPD)] blended with phenyl-C71-butyric acid methyl ester (PC71BM) are remarkably robust to process variations, optimizing under identical conditions for both spin and blade coating.
In situ TEM observation of the electrochemical lithiation of N-doped anatase TiO2nanotubes as anodes for lithium-ion batteries
Authors: Zhang Minghao , Yin Kuibo , Hood Zachary D. , Bi Zhonghe , Bridges Craig A. , Dai Sheng , Meng Ying Shirley , Paranthaman Mariappan Parans , Chi Miaofang
Published: September 2017

The effects of N-doping and the lithiation mechanism of TiO2nanotubes were elucidated by integratedin situmicroscopy and electrochemical measurements.
CO2electoreduction reaction on heteroatom-doped carbon cathode materials
Authors: Liu TianFu , Ali Sajjad , Lian Zan , Li Bo , Su Dang Sheng
Published: September 2017

This highlight summarizes the recent developments of heteroatom-doped carbon cathode catalysts for CERR.
Carbon-coated graphene/antimony composite with a sandwich-like structure for enhanced sodium storage
Authors: Wang Jinzuan , Yang Jun , Yin Wenyan , Hirano Shin-ichi
Published: September 2017

A carbon-coated graphene/antimony composite (G@Sb@C) with a sandwich-like structure has been synthesized and it exhibits superior electrochemical performances for sodium storage.
Enhanced hydrogen production from ammonia borane using controlled plasmonic performance of Au nanoparticles deposited on TiO2
Authors: Jo Seongwon , Verma Priyanka , Kuwahara Yasutaka , Mori Kohsuke , Choi Wonyong , Yamashita Hiromi
Published: September 2017

Mechanisms for hydrogen production from ammonia borane using plasmonic performance of Au nanoparticles deposited on TiO2have been investigated systematically.
A highly selective dual-therapeutic nanosystem for simultaneous anticancer and antiangiogenesis therapy
Authors: He Lizhen , Huang Yanyu , Chang Yanzhou , You Yuanyuan , Hu Hao , Leong Kam W. , Chen Tianfeng
Published: September 2017

Herein we design a dual-therapeutic MSNs nanosystem to realize simultaneous anticancer and antiangiogenesis by disrupting tumor neovasculature, cut off the nutrition supply, and kill cancer cells directly.
An improved finite‐state predictive torque control for switched reluctance motor drive
Authors: Li Cunhe , Wang Guofeng , Li Yan , Xu Aide
Published: September 2017

This study proposes an improved finite‐state predictive torque control (FS‐PTC) to minimise the torque ripples of switched reluctance motor (SRM) drive. Firstly, based on the accurate analytical method, a discrete time model is established for predicting the future states of SRM drive system. Secondly, to reduce the computational burden, a new switching table is constructed for the predictive controller by using the sector partition technique. Further, the torque ripple, copper losses, and average switching frequency are considered synchronously by using a multi‐objective cost function. As a result, the proposed FS‐PTC method not only can minimise the torque ripple but also can reduce effectively the copper losses and average switching frequency. Finally, the experimental results are carried out for a three phase 12/8 poles 1.5 kW SRM with the proposed control algorithm and the results are compared with conventional direct instantaneous torque control algorithm. These results demonstrate the effectiveness of the proposed method.
Tuned‐TSC based SVC for reactive power compensation and harmonic reduction in unbalanced distribution system
Authors: Das Sankar , Chatterjee Debashis , Goswami Swapan K.
Published: September 2017

A reactive power compensation scheme along with harmonic reduction technique for an unbalanced four‐wire system has been addressed in this study. The proposed compensation scheme can mitigate a wider range of thyristor controlled reactor (TCR) injected harmonics and load harmonics up to specified range. The scheme is realised by using a combination of thyristor controlled delta ()‐connected and star (Y)‐connected static VAr compensator (SVC). Each SVC consists of a TCR and a tuned‐thyristor switched capacitor (t ‐TSC). The proposed SVC scheme can eliminate negative sequence current with source power factor improvement through ‐SVC and zero sequence current caused by unbalanced load is removed by Y‐SVC. For harmonic compensation, the tuned‐TSC is used to filter harmonics generated by the non‐linear load or due to TCR switching in SVC. An optimised switching function is also adopted in the proposed scheme to minimise TCR harmonic injection in the SVC which reduces the required filter size. The optimised switching angles are computed off‐line using gravitational search algorithm and stored in microcontroller memory for on‐line applications. The proposed scheme has been validated through proper simulations using MATLAB software backed by suitable experimental results on a practical system.
Dynamic performance improvement of New York state power grid with multi‐functional multi‐band power system stabiliser‐based wide‐area control
Authors: Rimorov Dmitry , Heniche Annissa , Kamwa Innocent , Babaei Saman , Stefopolous George , Fardanesh Bruce
Published: September 2017

This study demonstrates the application of a wide‐area control scheme based on multi‐functional multi‐band power system stabilisers (MF‐MBPSS) in New York State grid for the purpose of system stability improvement. The aspects of oscillation damping, frequency and voltage closed‐loop control are considered. The study describes useful techniques for placing and tuning of MF‐MBPSSs based on simulation models and suitable techniques for very large power grids. The application of these concepts is demonstrated on a transient stability model of Eastern Interconnection. Results show a reduction of system frequency nadir during generation outages, significant improvement in damping of post‐disturbance swings and capabilities to contribute to long‐term voltage stability using only a modest amount of dynamic reactive power resources.