bluuebunny/crossref_metadata_2025 huggingface dataset:
Viral Hepatitis A, B and C in a Group of Transgender Women in Central Brazil
Authors: Ferri Lucila Pessuti , Junqueira Priscilla dos Santos , de Almeida Mayara Maria Souza , Oliveira Mariana Gomes , de Oliveira Brunna Rodrigues , Diniz e Silva Bruno Vinícius , Magalhães Larissa Silva , Villar Lívia Melo , Caetano Karlla Antonieta Amorim , Souza Márcia Maria , Carneiro Megmar Aparecida dos Santos , Martins Regina Maria Bringel , Teles Sheila Araujo
Published: September 2022

Transgender women (TGW) have limited access to affordable viral hepatitis testing, hepatitis B vaccination, and treatment. We aimed to estimate the prevalence of viral hepatitis A, B, and C, as well as to compare the adherence and immunogenicity of two hepatitis B vaccine schedules among TGW in Central Brazil. A total of 440 TGW were interviewed and tested for hepatitis A, B, and C serological markers from 2017 to 2018. The hepatitis B vaccine was offered to 230 eligible TGW: 112 received a super accelerated hepatitis B vaccine schedule (G1) and 118 a standard schedule (G2). The antibody against the hepatitis A virus (HAV) was detected in 75.63% of the participants, and 12.3% of the TGW were exposed to the hepatitis B virus (HBV). Two (0.46%) participants were HBV carriers. Only 41.5% of the participants showed a serological profile of hepatitis B vaccination. The antibody against the hepatitis C virus (anti-HCV) was found in six participants (1.37%). Of the TGW who received the first vaccine dose, 62 (55.36%) and 49 (41.52%) in G1 and G2, respectively, received three doses (p = 0.036). The vaccine response was evaluated in 28 G1 and 22 G2 TGW; of these, 89.3% and 100% developed protective anti-hepatitis B surface-antigen titers, respectively (p = 0.113). Since one-third of younger transgender women are susceptible to HAV, hepatitis B immunization is low, and the anti-HCV rate is higher in this group than in the general population in Central Brazil, public-health attention is warranted. The super-accelerated scheme demonstrated better adhesion and good immunogenicity, suggesting that it would be a more cost-effective solution.
Bianchi I Spacetimes in Chiral–Quintom Theory
Authors: Paliathanasis Andronikos
Published: September 2022

In this paper, we study anisotropic exact solutions in the homogeneous Bianchi I background geometry in a multifield theory. Specifically, we consider the Chiral–Quintom theory, which is an extension of the Chiral theory, because at least one of the scalar fields can have negative energy density. Moreover, the Quintom theory can be recovered when one of the free parameters of the theory vanishes. We find that Kasner-like and anisotropic exponential solutions exist for specific functional forms of the scalar field potential. Finally, Noether symmetry analysis is applied for the classification of the theory according to the admitted symmetries. Conservation laws are determined, while we show that the Kasner-like solution is the analytic solution for the given model.
COVID-19 Vaccination Policies: Ethical Issues and Responsibility
Authors: Marrone Maricla , Buongiorno Luigi , Stellacci Alessandra , Cazzato Gerardo , Stefanizzi Pasquale , Tafuri Silvio
Published: September 2022

The World Health Organization (WHO) declared coronavirus 2 (SARS-CoV-2, COVID-19) a global pandemic on 11 March 2020. The emergence of the reliability of vaccines, the fear of possible vaccination-related side effects, and mass-media information created situations in which families and even health professionals developed hesitations regarding the need for vaccines, with a consequent decrease in vaccination coverage. This study discusses ethical issues and responsibility for the possible side effects of SARS-CoV-2 vaccination raised by vaccination policies.
Determinants of COVID-19 Vaccine Acceptance among Dental Professionals: A Multi-Country Survey
Authors: Nassani Mohammad Zakaria , Noushad Mohammed , Rastam Samer , Hussain Mudassir , Alsalhani Anas B. , Al-Saqqaf Inas Shakeeb , Alali Faisal Mehsen , Demachkia Amir Mohiddin , de Melo Renata Marques , Arshad Mohammed , Luddin Norhayati , Husein Adam , Qamar Zeeshan , Koppolu Pradeep , Darwish Mahmoud , Nassar Ahmad Salim Abdalla , Habib Adnan , Suleyman Firas , Khanam H. M. Khuthija , Yousief Salah A. , Al-Maweri Sadeq Ali , Tabassum Nafeesa , Samran Abdulaziz , Dimashkieh Mohiddin R. , Al-Awar Mohammed Sadeg , Tarakji Bassel
Published: September 2022

Purpose: This study sought to investigate the acceptance rate and associated factors of COVID-19 vaccines among dentists and dental students in seven countries. Material and Methods: A structured questionnaire prepared and guided by the report of the SAGE Working Group on Vaccine Hesitancy was distributed among groups of dentists and dental students in seven countries across four continents. Results: A total of 1527 subjects (850 dentists and 677 dental students) participated in this survey. Although 72.5% of the respondents reported their intention to accept COVID-19 vaccines (dentists: 74.4%, dental students: 70.2%), there was a significant difference in agreement between dentists/dental students across countries; generally, respondents in upper-middle-, and high-income countries (UM-HICs) showed significantly higher acceptance rates compared to those in low- and lower-middle income countries (L-LMICs). Potential predictors of higher vaccine acceptance included being a dentist, being free of comorbidity, being well-informed about COVID-19 vaccines, having better knowledge about COVID-19 complications, having anxiety about COVID-19 infection, having no concerns about the side effects of the produced vaccines and being a resident of an UM-HIC. Conclusion: The results of our survey indicate a relatively good acceptance rate of COVID-19 among the surveyed dentists and dental students. However, dentists and dental students in L-LMICs showed significantly lower vaccine acceptance rates and trust in COVID-19 vaccines compared to their counterparts in UM-HICs. Our results provide important information to policymakers, highlighting the need for implementation of country-specific vaccine promotion strategies, with special focus on L-LMICs.
Gene Signatures of T-Cell Activation Can Serve as Predictors of Functionality for SARS-CoV-2-Specific T-Cell Receptors
Authors: Mateyka Laura M. , Strobl Philipp M. , Jarosch Sebastian , Scheu Sebastian J. C. , Busch Dirk H. , D’Ippolito Elvira
Published: September 2022

The importance of T cells in controlling SARS-CoV-2 infections has been demonstrated widely, but insights into the quality of these responses are still limited due to technical challenges. Indeed, understanding the functionality of the T-cell receptor (TCR) repertoire of a polyclonal antigen-specific population still requires the tedious work of T-cell cloning or TCR re-expression and subsequent characterization. In this work, we show that it is possible to discriminate highly functional and bystander TCRs based on gene signatures of T-cell activation induced by recent peptide stimulation. SARS-CoV-2-specific TCRs previously identified by cytokine release after peptide restimulation and subsequent single-cell RNA sequencing were re-expressed via CRISPR-Cas9-mediated gene editing into a Jurkat-based reporter cell line system suitable for high-throughput screening. We could observe differences in SARS-CoV-2 epitope recognition as well as a wide range of functional avidities. By correlating these in vitro TCR engineered functional data with the transcriptomic profiles of the corresponding TCR-expressing parental T cells, we could validate that gene signatures of recent T-cell activation accurately identify and predict truly SARS-CoV-2-specific TCRs. In summary, this work paves the way for alternative approaches useful for the functional analysis of global antigen-specific TCR repertoires with largely improved throughput.
Characteristics and Roles of T Follicular Helper Cells in SARS-CoV-2 Vaccine Response
Authors: Chi Xuyang , Gu Jia , Ma Xiaoxue
Published: September 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is critical to controlling the coronavirus disease 2019 (COVID-19) pandemic. However, a weak response to the vaccine and insufficient persistence of specific antibodies may threaten the global impact of mass vaccination campaigns. This study summarizes the internal factors of the body that affect the effectiveness of the SARS-CoV-2 vaccine. T follicular helper (Tfh) cells support germinal center B cells to produce vaccine-specific immunoglobulins. A reduction in the Tfh cell number and a shift in the subset phenotypes caused by multiple factors may impair the production and persistence of high-affinity antibodies. Besides efficacy differences caused by the different types of vaccines, the factors that affect vaccine effectiveness by intervening in the Tfh cell response also include age-related defects, the polarity of the body microenvironment, repeated immunization, immunodeficiency, and immunosuppressive treatments. Assessing the phenotypic distribution and activation levels of Tfh cell subsets after vaccination is helpful in predicting vaccine responses and may identify potential targets for improving vaccine effectiveness.
Trial Evaluation of Protection and Immunogenicity of Piscine Bivalent Streptococcal Vaccine: From the Lab to the Farms
Authors: Kannika Korntip , Sirisuay Soranut , Kondo Hidehiro , Hirono Ikuo , Areechon Nontawith , Unajak Sasimanas
Published: September 2022

Streptococcosis is one of the major diseases that causes devastation to farmed fish, leading to significant economic losses all around the world. Currently, two serotypes of Streptococcus agalactiae, serotype Ia and III, have been identified as virulent strains and major causative agents of the disease in farmed Nile tilapia (Oreochromis niloticus Linn.) in Thailand. Upon inactivated vaccine development, monovalent inactivated whole-cell vaccines demonstrated high specific antibody production against homologous serotypes and limited production with heterologous serotypes. However, for higher efficacy, a bivalent streptococcal vaccine was designed to maximize protective immunity to both serotypes. Interestingly, our bivalent vaccine could successfully induce specific antibody production against both serotypes with similar levels, and the response could extend over the 8 weeks of the experimental period. Evaluation of vaccines in the laboratory scale revealed relative percent survival (RPS) of vaccinated tilapia to serotype Ia (81.2 ± 9.4%) and serotype III (72.2 ± 4.8%), respectively. The efficacy of the bivalent vaccine showed significant RPS higher than the monovalent vaccine (p < 0.05) at 30 days, and the protection of all those vaccines was reduced thereafter. Evaluation of the vaccine in a farm trial in different locations in Thailand revealed the efficacy of the bivalent vaccine in increasing the production yield by greater than 80% in all tested farms in 2015 and 2021. Taken together, this study affirms the efficacy of the bivalent streptococcal vaccine in the prevention of streptococcus disease in Nile tilapia, which could be used in different areas. This vaccine development could be effectively applied in the tilapia culture industry.
A Vaccine for Canine Rocky Mountain Spotted Fever: An Unmet One Health Need
Authors: Walker David H. , Blanton Lucas S. , Laroche Maureen , Fang Rong , Narra Hema P.
Published: September 2022

Outbreaks of life-threatening Rocky Mountain spotted fever in humans and dogs associated with a canine-tick maintenance cycle constitute an important One Health opportunity. The reality of the problem has been observed strikingly in Mexico, Brazil, Colombia, and Native American tribal lands in Arizona. The brown dog tick, Rhipicephalus sanguineus sensu lato, acquires the rickettsia from bacteremic dogs and can maintain the bacterium transtadially to the next tick stage. The subsequent adult tick can then transmit infection to a new host, as shown by guinea pig models. These brown dog ticks maintain spotted fever group rickettsiae transovarially through many generations, thus serving as both vector and reservoir. Vaccine containing whole-killed R. rickettsii does not stimulate sufficient immunity. Studies of Rickettsia subunit antigens have demonstrated that conformationally preserved outer-membrane autotransporter proteins A and B are the leading vaccine candidates. The possibility of a potentially safe and effective live attenuated vaccine has only begun to be explored as gene knockout methods are applied to these obligately intracellular pathogens.
Cost-Effectiveness Analysis of Cell Versus Egg-Based Seasonal Influenza Vaccination in Children and Adults in Argentina
Authors: Urueña Analía , Micone Paula , Magneres María Cecilia , McGovern Ian , Mould-Quevedo Joaquin , Sarmento Túlio Tadeu Rocha , Giglio Norberto
Published: September 2022

Background: Quadrivalent cell-based influenza vaccines (QIVc) avoid egg-adaptive mutations and can be more effective than traditional quadrivalent egg-based influenza vaccines (QIVe). This analysis compared the cost-effectiveness of QIVc and QIVe in Argentinian populations < 65 years old from the payer and societal perspectives. Methods: A static decision tree model compared the costs and health benefits of vaccination with QIVc vs. QIVe using a one-year time horizon. The relative vaccine effectiveness of QIVc vs. QIVe was assumed to be 8.1% for children and 11.4% for adults. An alternative high egg-adaptation scenario was also assessed. Model inputs were sourced from Argentina or the international literature. Deterministic and probabilistic sensitivity analyses were performed. Results: Compared to QIVe, QIVc would prevent 17,857 general practitioner visits, 2418 complications, 816 hospitalizations, and 12 deaths per year. From the payers’ perspective, the incremental cost-effectiveness ratio per quality-adjusted life years gained was USD12,214 in the base case and USD2311 in the high egg-adaptation scenario. QIVc was cost-saving from the societal perspective in both scenarios. Conclusions: QIVc in Argentina would be cost-effective relative to QIVe. The potential health benefits and savings would be even higher in high egg-adaptation seasons.
Vaccination Offer during the Occupational Health Surveillance Program for Healthcare Workers and Suitability to Work: An Italian Retrospective Cohort Study
Authors: Bianchi Francesco Paolo , Stefanizzi Pasquale , De Maria Luigi , Martinelli Andrea , Diella Giusy , Larocca Angela Maria Vittoria , Vimercati Luigi , Tafuri Silvio
Published: September 2022

The active immunization of health care workers (HCWs) is a crucial measure to avoid nosocomial infection; nevertheless, vaccine coverage (VC) among health personnel in Italy is unsatisfactory. To improve VC in the healthcare set, the Hygiene and Occupational Medicine departments of Bari Policlinico General University Hospital applied a specific program. The operative procedure demands that in the context of the occupational medical examination, all workers are evaluated for susceptibility to vaccine-preventable diseases (VDPs), with immunization prophylaxis offered to those determined to be susceptible. This study analyzed data from workers who attended the biological risk assessment protocol from December 2017 to October 2021 (n = 1477), who were evaluated for the immune status for measles, mumps, rubella, and varicella. Among the enrolled subjects, non-protective antibody titers were higher for measles and mumps (13%), followed by rubella (11%) and varicella (8%). Appropriate vaccinations were offered to all susceptible HCWs, and HCWs were re-tested one month after immunization. The seroconversion rate after the administration of one or more booster dose(s) was over 80%. Overall, 2.5% of the subjects refused the offered vaccine(s); the main determinant of immunization compliance was younger age (aOR = 0.86; 95%CI = 0.80–0.92). Especially during the COVID-19 pandemic, VPDs may still present a hazard in nosocomial environment. Our experience suggests that, despite hospital procedures and dedicated human assets, satisfactory VC cannot be reached without the provision of federal regulations. Nevertheless, public health policymakers have to improve the promotion of vaccine prophylaxis and education to reach higher VC.
COVID-19 Vaccine Acceptance among Vulnerable Groups: Syrian Refugees in Jordan
Authors: Talafha Qusai M. , Al-Haidose Amal , AlSamman Ala Y. , Abdallah Saja A. , Istaiteyeh Rasha , Ibrahim Wisam Nabeel , Hatmal Ma’mon M. , Abdallah Atiyeh M.
Published: September 2022

Despite the wide distribution of COVID-19 vaccines, refugees remain last in line for the intake of vaccines. Syrian refugees in Jordan reach up to 700,000 registered and almost up to 700,000 unregistered refugees. This study aims to assess the willingness of Syrian refugees in Jordan to take the COVID-19 vaccine. Participants in the Zaatari refugee camp in Jordan were invited through social media to complete the survey between January and March 2022. A total of 230 refugees participated in our study, with almost half the participants of male gender. The majority of the participants had secondary school as their highest education level and were unemployed, being below the social poverty line. Interestingly, Syrian refugees showed a high vaccine acceptance rate, as 89.6% were willing to take the vaccine. Moreover, they showed high knowledge regarding the vaccine, the disease, and the virus. Our findings highlight the importance of knowledge and awareness of the COVID-19 vaccine to increase the acceptance rate. This is very important as refugees represent a vulnerable group to infection and complications and require close attention, especially with their significant numbers in Jordon and challenges of providing adequate vaccine supplies at their camps. We hope that, with proper dissemination of knowledge and awareness and with easy accessibility to the vaccines, it will ensure high immunization to reach herd immunity in Jordan.
Intentions of Patients with Hypertension to Receive a Booster Dose of the COVID-19 Vaccine: A Cross-Sectional Survey in Taizhou, China
Authors: Ying Chen-Qian , Lin Xiao-Qing , Lv Li , Chen Yan , Jiang Jian-Jun , Zhang Yun , Tung Tao-Hsin , Zhu Jian-Sheng
Published: September 2022

COVID-19 patients with hypertension have increased hospital complications and mortality rates. Moreover, these patients also have lower antibody titers after receiving the coronavirus disease (COVID-19) vaccine. Therefore, patients with hypertension should receive a COVID-19 vaccine booster. To promote the uptake of COVID-19 vaccine booster among hypertensive patients, this study investigated patients’ willingness and factors that influence patients with hypertension to receive the COVID-19 vaccine booster. From July 2021 to August, 410 patients with hypertension were surveyed. Overall, 76.8% of patients were willing to receive the COVID-19 vaccine booster, as 82.7% of patients without comorbidities and 72.7% of patients with comorbidities were willing to receive the vaccine booster. The main factors that influenced the willingness of patients with hypertension to receive a booster dose were the preventive effect of the vaccine (χ2 = 52.827, p < 0.05), vaccine safety (χ2 = 42.423, p < 0.05), vaccine knowledge (χ2 = 7.831, p < 0.05), presence of comorbidities (χ2 = 4.862, p < 0.05), disease control (χ2 = 5.039, p < 0.05), and antihypertensive treatments (χ2 = 12.565, p < 0.05). This study’s findings highlight the need to promote knowledge about booster vaccination among patients and health management. These measures would improve patients’ willingness and knowledge about the vaccine and their health status, which are the main factors that influence patients’ intention to receive booster vaccines.
Detecting the Flame Front Evolution in Spark-Ignition Engine under Lean Condition Using the Mask R-CNN Approach
Authors: Petrucci Luca , Ricci Federico , Martinelli Roberto , Mariani Francesco
Published: September 2022

In the wake of previous works, the authors propose a new approach for the identification and evolution of the flame front in an optical SI engine. Currently, it is an essential prerogative to characterize the capability of innovative igniters to guarantee earlier flame development in critical operating conditions, such as ultra-lean mixture, towards which automotive research is moving to deal with the ever more stringent regulations on pollutant emissions. The core of the new approach lies in the R-CNN Mask method. The latter consists of a conceptually simple and general framework for object instance segmentation. It can efficiently detect objects contained in an image while simultaneously generating a high-quality segmentation mask for each instance. In particular, the aim this work is to develop an automatized algorithm for detecting, as objectively as possible, the flame front evolution of lean/ultra-lean mixtures ignited by low-temperature plasma-based ignition systems. The capability of the Mask R-CNN algorithm to automatically estimate the binarized area, without setting a defined binarized threshold, allows us to perform an analysis of the flame front evolution completely independent from the user interpretation. Mask R-CNN can detect the kernel in advance and can identify events as regular combustions instead of misfires or anomalies if compared to other traditional approaches. These features make the proposed method the most suitable option to analysis the real behavior of the innovative ignition systems at critical operating conditions.
The Variation of Serotonin Values in Dogs in Different Environmental Conditions
Authors: Bochiș Timea Andrea , Imre Kálmán , Marc Simona , Vaduva Cristina , Florea Tiana , Dégi János , Voia Octavian Sorin , Pop Călin , Ţibru Ioan
Published: September 2022

Serotonin is considered to be the neurotransmitter that controls several types of behavior: aggressiveness, impulsivity, food selection, stimulation, sexual behavior, reaction to pain, and emotional manifestations. The aim of this study was to determine the serotonin values in 43 dogs, divided into three different experimental variants: (1) between two groups of medium (n = 6) and small (n = 4) breed shelter dogs; (2) in dogs with (n = 15) and without (n = 10) owners after administration of pre-spaying/neutering anesthesia; (3) in different behavioral states (n = 8) classified as follows: M1—happy, M2—aggressive, M3—calmed status, post-exposure to a stressful situation, compared to the reference time referred to as M0. There were no significant differences (p ≥ 0.05) regarding the serotonin values between the two groups of medium and small breed shelter dogs. Following anesthesia, the average mean serotonin values were significantly lower (p ≤ 0.003), by 63.85 ng/mL, in stray dogs compared to dogs with owners. No significant differences (p ≥ 0.05) were found when comparing the reference time M0 to M1, M2, and M3. The differences decreased significantly (p ≤ 0.05), by 89.61 ng/mL, between M1 and M2 and increased significantly (p ≤ 0.008), by 112.78 ng/mL, between M2 and M3.
The Novel Diagnostic Techniques and Biomarkers of Canine Mammary Tumors
Authors: Kaszak Ilona , Witkowska-Piłaszewicz Olga , Domrazek Kinga , Jurka Piotr
Published: September 2022

Canine mammary tumors (CMTs) are considered a serious clinical problem in older bitches. Due to the high malignancy rate and poor prognosis, an early diagnosis is essential. This article is a summary of novel diagnostic techniques as well as the main biomarkers of CMTs. So far, CMTs are detected only when changes in mammary glands are clinically visible and surgical removal of the mass is the only recommended treatment. Proper diagnostics of CMT is especially important as they represent a very diverse group of tumors and therefore different treatment approaches may be required. Recently, new diagnostic options appeared, like a new cytological grading system of CMTs or B-mode ultrasound, the Doppler technique, contrast-enhanced ultrasound, and real-time elastography, which may be useful in pre-surgical evaluation. However, in order to detect malignancies before macroscopic changes are visible, evaluation of serum and tissue biomarkers should be considered. Among them, we distinguish markers of the cell cycle, proliferation, apoptosis, metastatic potential and prognosis, hormone receptors, inflammatory and more recent: metabolomic, gene expression, miRNA, and transcriptome sequencing markers. The use of a couple of the above-mentioned markers together seems to be the most useful for the early diagnosis of neoplastic diseases as well as to evaluate response to treatment, presence of tumor progression, or further prognosis. Molecular aspects of tumors seem to be crucial for proper understanding of tumorigenesis and the application of individual treatment options.
Influence of Using Various Levels of Protein Concentrate in Rations of Ayrshire Dairy Cows on Rumen Microbiome, Reproductive Traits and Economic Efficiency
Authors: Buryakov Nikolai P. , Aleshin Dmitrii E. , Buryakova Maria A. , Zaikina Anastasya S. , Laptev Georgy Y. , Ilina Larisa A. , Petrov Aleksandr S. , Kostomakhin Nikolay M. , Sheikh Ahmed I. El , Sahwan Ferial M. , Fathala Mohamed M.
Published: September 2022

Animal feeding research has revealed a close relationship between the chemical composition and nutritional value of cow rations, the number of rumen bacterial communities and animal productivity. Our present research aimed to investigate the outcome of inclusion of different levels of protein concentrate in rations of Ayrshire dairy cows in relation to the rumen microbiome, reproductive traits and economic value. Forty-five Ayrshire cows were divided into three groups (15 in each). The first control group 0 AM was fed the basal ration, while the second 1 AM and third 2 AM groups were fed the basic ration with the sunflower cake replaced by different levels of protein concentrate Agro-Matic (1 and 1.5 kg/head/day, respectively). Ruminal fluid samples, reproductive parameters and economic value were studied. During the early lactation period, 120 days in milk (DIM), the number of pathogenic microorganisms decreased in both the 1 AM and 2 AM groups when compared with the control group 0 AM; moreover, a significant decrease in Peptococcus bacteria was recorded in the 1 AM group, while Fusobacterium decreased in the 2 AM group. At the end of lactation, the total number of cellulolytic bacteria increased with the use of protein concentrate in animals of the 1 AM group when compared with the control group. Regarding undesirable bacteria, the 2 AM group recorded the highest value for Lactobacilli and Actinobacteria when compared with the 0 AM group (0.18 and 8.90 vs. 0.04 and 4.24), and the differences were significant (p < 0.05). The insemination index and the duration of the days open period decreased in the 2 AM group, while the differences were p > 0.05. The profitability of milk production increased by 2.76% and 6.28% in both supplemented groups, and the differences compared to the 0 AM group were significant. We conclude that the supplementation of Agro-Matic caused no deviations from the normal standards of cellulolytic, amylolytic, transit and pathogenic bacteria, no impact on reproductive functions and significantly improved the profitability of the milk production process of Ayrshire dairy cows.
Endoparasites Infecting Domestic Animals and Spectacled Bears (Tremarctos ornatus) in the Rural High Mountains of Colombia
Authors: Zárate Rodriguez Paula Tatiana , Collazos-Escobar Luisa Fernanda , Benavides-Montaño Javier Antonio
Published: September 2022

This research described the co-infection prevalence of endoparasites in Tremartus ornatus and domestic animals in the rural high mountains of Colombia by copro-parasitological examination. Some parasites have a zoonotic potential in wild endangered species and domestic animals in Colombian regions. T. ornatus had a notable infection with Eimeria spp., Ascaris spp., Ancylostoma spp., and Baylisascaris spp. Cryptosporidium spp., Balantidium coli, Anoplocephala spp., and Acanthamoeba spp. In B. taurus, Eimeria spp. is coinfecting with Cryptosporidium spp. (6.6%) and represents 18% of the total parasitism. In E. caballus and B. taurus. Eimeria spp. coinfecting (34.7%), with the Strongylus spp. (21.9–25%). In T. ornatus, Eimeria spp. is coinfecting with Ancylostoma spp. (36.2%), Cryptosporidium spp., Ascaris spp., Baylisascaris spp., and B. coli.
Novel Battery Module Design for Increased Resource Efficiency
Authors: Schmidt Simon , Clausen Jan , van der Auwera Robin , Klapp Oliver , Schmerler Rico , Löffler David , Werner Maximilian Jakob , Block Lukas
Published: September 2022

The work presented focuses on a material efficient, modular design of a battery module for vehicle applications. Furthermore, the possibility of disassembly of individual components was considered. The constructive design focused on the combination of cast aluminum components, lightweight composites panels, and aluminum-foam phase-change material (PCM) composites. This led to an innovative battery module, which was finally implemented on a demonstrator level. The required cooling power of the module could be reduced by approx. 20% compared to conventional battery module setups. Furthermore, the constructive design of the module and the use of a “debonding-on-demand” technology enabled significantly faster disassembly. Die to the combination of these advantages and the possibility to give individual parts of the module a second life for new modules, the module shows a high resource efficiency as well as high CO2 savings potential.
Apresentação de Les Temps Modernes
Authors: Vidal Filho Fernando
Published: September 2022

Nota introdutória
Tradução: Apresentação de Les Temps Modernes
Tradução: Escrever para sua época
ENGINEERING CALCULATION OF THE PARAMETERS OF THE TRAVEL POCKET ON TO A STOP OF PASSENGER URBAN TRANSPORT
Authors: Zelikov V. , Denisov G. , Klimova G. , Strukov Yu. , Zlobina N.
Published: September 2022

The issues of designing the route network of urban passenger transport and the need for the device of travel pockets for it are considered. It is proposed to use mathematical statistics formulas to calculate the probability of the number of simultaneous appearance of public transport units at a stop. The procedure for calculating the length of the entrance pocket at the stop using the results of visual observation of the entrance to the stop of passenger transport units is given. The length of the entry pocket iscalculated for the simultaneous appearance at the stop of two buses of large and one bus of small capacity, which was 68 m.
ANALYSIS OF CONFLICTS IN THE INTERACTION OF THE VEHICLE AND PEDESTRIAN STREAM
Authors: Busarin E. , Dorokhin Sergey , Belokurov V. , Busarina A.
Published: September 2022

A technique for studying the interaction between traffic and pedestrian traffic at controlled intersections and its impact on pedestrian safety is described. The analysis of conflict situations in the interaction of a vehicle and a pedestrian is carried out, as well as recommendations are given for the application of additional measures aimed at improving the efficiency of traffic organization.
IMPACT OF CARDIO TRAINING ON THE BODY
Authors: Grigoreva I. , Volkova E. , Belikova I.
Published: September 2022

The article discusses the effectiveness and variety of cardio training and their benefits. Lack of physical activity in our lives can lead to a whole range of diseases. Cardio loads can strengthen our body and improve well-being. When using cardio loads, the activity of the circulatory system, heart, respiratory organs improves, endurance increases.
Psychological aspects of religious morality in middle and late adulthood
Authors: Tatala Małgorzata
Published: September 2022

As a result of the study, the structure of religious morality including the following categories was distinguished: basis of moral functioning, moral attitude toward conflict situations, moral attitude toward experienced dissonances, and reference to the principle of moral autonomy. For the basis of moral functioning, the following subcategories were identified: Self, others, religion, consequences. For the moral attitude to conflict situations, the subcategories were: task-oriented, avoidant, emotional, religious. For the moral attitude toward experienced dissonances, the categories were: informational-religious, normative, avoidant, conflictual. With respect to the principle of moral autonomy, these were: congruence and incongruence. The participants of the study were 120 people of the Catholic faith, 60 each in middle and late adulthood. A Piagetian exploratory-critical interview was used, the design of which was based on Walesa's model of religiosity. The frequency of specific subcategories of religious morality was significantly differentiated by the age of the subjects for the basis of moral functioning, moral attitude toward conflict situations, and moral attitude toward experienced dissonance. In late adulthood, religiosity serves an important function - especially in situations of conflict or events related to experienced moral dissonances.
For the benefit of man – personalistic aspects of John Paul II’s thought
Authors: Żukowska-Gardzińska Dominika
Published: September 2022

The Encyclical Redemptor hominis, which was the programme of John Paul II's pontificate, included in its guiding principle not only the conviction that man's destiny is bound to Christ, but also a reflection on the individual and social nature of the human person. In the Pope's teaching, knowledge about oneself and one's reality appears as a commitment to action, to taking responsibility in the spirit of the personalistic norm formulated by him, that is, the conviction that every human being is entitled to love because he is a person. This one simple sentence can be called the axis of Karol Wojtyla's action and conduct, which is realized through a triad of mutually derived attitudes. They are the principle of participation, dialogue and leadership. This article is devoted to the discussion of this triad and the order of dependencies between them.
واقع الإعداد النفسي لدى لاعبي المنتخبات الوطنية الأردنية للالعاب الفردية خلال انتشار فيروس كورونا
Authors: زريقات د. عايد
Published: September 2022

هدفت الدراسة التعرف إلى واقع الإعداد النفسي لدى لاعبي المنتخبات الوطنية الأردنية للالعاب الفردية خلال انتشار فيروس كورونا، بالإضافة إلى مستوى الأكتئاب والقلق هؤلاء اللاعبين في ظل تفشي وباء فيروس كورونا. ولتحقيق ذلك استخدم الباحثان المنهج الوصفي على عينة تكونت من (ن= 54). ولتقليل التفاعل وجهاَ لوجه تم بناء إستبيان الكتروني باستخدام (استبانة جوجل) حيث تكونت بصورتها النهائية من (28) فقرة تناولت الاكتئاب والقلق والوسائل النفسية المستخدمة مع اللاعبين. حيث ارتبطت (12) فقرة  بالاكتئاب والقلق، و (16) فقرة ارتبطت بالوسائل النفسية المستخدمة. ولمعالجة البيانات احصائياً تم إستخدام المتوسطات الحسابية والانحرفات المعيارية والنسب المئوية. وأظهرت نتائج الدراسة أن مستوى الاكتئاب والقلق كان مرتفعاً لدى عينة الدراسة وبمتوسط (0.48 ±2.44)، ومتوسط استخدام الوسائل النفسية للاعبين خلال الحجر المنزلي جاء بدرجة منخفضة وبنسبة مئوية (29.63)%. ويوصي الباحثان بضرورة ضرورة استخدام استراتيجيات جديدة لتقديم الرعاية النفسية لهؤلاء اللاعبين في ظل الحجر المنزلي.
كلمات مفتاحية: الاكتئاب، القلق، فيروس كورونا، الوسائل النفسية، اللالعاب الفردية.
توجّهات البحث الموضوعيّة في التربية اللُّغويّة في المملكة العربيّة السعوديّة: "دراسة تحليليّة لرسائل الماجستير وأطروحات الدكتوراه"
Authors: خليفة الحربي تركي , علي الخوالدة د. محمد
Published: September 2022

هدفت الدّراسة الحالية إلى تعرّف توجّهات البحث الموضوعية في التربية اللغوية في المملكة العربية السعودية "دراسة تحليلية لرسائل الماجستير وأطروحات الدكتوراه". ولتحقيق هدف الدّراسة، اتّبع الباحثان المنهج الوصفي، بتحليل محتوى جميع الرسائل والأطروحات في تعلم اللغة العربية وتعليمها المجازة في جامعة أم القرى في الفترة (1976-2020) البالغ عددها (231) رسالة وأطروحة. أظهر التحليل الإحصائي للتكرارات والنسب المئوية عددًا من التوجّهات الموضوعية في المنهج، والمتعلم، والمعلم، وفروع اللغة ومهاراتها. وفي ضوء النتائج، قدّمت الدّراسة عددًا من التوصيات، أهمّها: توجيه الباحثين إلى استهداف مرحلة رياض الأطفال في التعليم العام، ومرحلة الدّراسات العليا في التعليم الجامعي، والاهتمام بدراسة علم العروض.
الكلمات المفتاحية: توجّهات البحث الموضوعية، التربية اللغوية، رسالة الماجستير، أطروحة الدكتوراه.
التحليل الكينماتيكي للجانب المفضل وغير المفضل للاعبي المنتخبات الرياضية الأردنية في تمرين السكوات الخلفي بالبار
Authors: Mohammad Abu Touq Dr. Iyad , Mohamed Attiyat Dr. Khaled , Abdel Fattah Dr. Osamah
Published: September 2022

هدفت هذه الدراسة إلى التحليل الكينماتيكي للجانب المفضل وغير المفضل للاعبي المنتخبات الرياضية الأردنية في تمرين السكوات الخلفي بالبار من خلال التعرف إلى قيم بعض المتغيرات الكينماتية قيد الدراسة على الجانب المفضل وغير المفضل لدى لاعبي المنتخبات الوطنية الاردنية في شدد مختلفة، كذلك إلى الفروق في قيم هذه المتغيرات الكينماتية. ولتحقيق ذلك أستخدم الباحثون المنهج الوصفي على عينة تكونت من (15) لاعب، وتم اختيارهم بالطريقة العمدية، بحيث يتضمن تدريبهم السكوات لفترة لا تقل عن عامين. ولتصوير عينة الدراسة إسخدم الباحثون (3) كاميرات تم وضع إثنتا على المستوى الجانبي وواحدة على المستوى الامامي حيث تم تحليل أداء اللاعبين بإستخدام برنامج (Kinovea) للتحليل الحركي. وتناولت الدراسة العديد من المتغيرات الكينماتيكية كزاوية الظهر، الحوض، الركبة و ذراع العزم لمفصل الركبة. ولمعالجة بيانات الدراسة إستخدم الباحثون المتوسطات الحسابي، الإنحرافات المعيارية، الالتواء، إختبار ت واختبار ويلكوكسون.
درجة استخدام الشباب الأردني للتسوق الإلكتروني في ضوء بعض المتغيرات الديموغرافية
Authors: Ahmad Alomari Alaa , Imad Alomari Dr. Mohammad
Published: September 2022

هدفت هذه الدراسة إلى تحديد درجة استخدام الشباب الأردني للتسوق الإلكتروني في ضوء متغيرات الجنس، ومكان السكن، والمستوى الاقتصادي، ولتحقيق أهداف هذه الدراسة تم ترجمة مقياس التسوق الإلكتروني لشهازاد(Shahzad, 2015) ، وتطبيقه على عينة مكونة من (700) فردًا في محافظات إقليم الشمال الأردني، والمكون من محافظة إربد، وعجلون، وجرش، والمفرق. أظهرت النتائج أن درجة استخدام الشباب الأردني للتسوق الإلكتروني كانت ضعيفة، كما أظهرت النتائج عدم وجود اختلاف في استخدام الشباب الأردني للتسوق تعزى للمتغيرات: الجنس، ومكان السكن، والمستوى الاقتصادي في استجابات أفراد العينة على مقياس التسوق الإلكتروني.
الكلمات المفتاحية: التسوق الإلكتروني، الشباب الأردني.
أثر التحرير المالي على الاحتياطيات الأجنبية في الأردن
Authors: Ahead Alfarkh Aya , Ibrahim Malawi Prof. Ahmad
Published: September 2022

This study aimed to investigate the impact of financial liberalization on foreign reserves in Jordan over the period (1998-2018). Several diagnostic tests have been applied, such as Augmented Dickey- Fuller (ADF) and Phillips-Perron (PP) test for Stationarity.
The results have shown that all of the time series are not stationary in their levels, where are their first differences are stationaryaccording to Dickey- Fuller test (ADF), but the results have shown that some of the time series are stationary in their levels and some of them are stationary in the first difference according to Phillips-Perron test. Cusum stability test was applied for checking the stability of the model parameters, and the autoregressive distributed lag (ARDL) bound testing approach was applied for the cointegration test. The results have shown the financial freedom (as a proxy variable for financial liberalization) has a positive statistically significant impact on foreign reserves. So this study recommends to extend financial liberalization in order to increase foreign reserves in Jordan.
Keywords: Financial Liberalization, Foreign reserves, Autoregressive Distributed Lag (ARDL) model.
درجة ممارسة مديري المدارس للقيادة الابتكارية وعلاقتها بجودة الأداء المدرسي من وجهة نظر المعلمين
Authors: Jamil Albana Doaa , Mohammad alshairman Dr. Wael
Published: September 2022

هدفت الدراسة إلى معرفة درجة ممارسة مديري مدارس لواء وادي السير للقيادة الابتكارية وعلاقتها بجودة الأداء المدرسي، واستخدمت الدراسة المنهج الوصفي المسحي الارتباطي،  لتحقيق أهداف الدراسة قام الباحثان بإعداد إستبانتين، استبانة ممارسة مديري المدارس للقيادة الابتكارية واستبانة جودة الأداء المدرسي وتكونت عينة الدراسة من (388) معلماً ومعلمة في المدارس الحكومية والخاصة في لواء وادي السير تم اختيارهم بالطريقة العشوائية البسيطة. وتوصلت الدراسة إلى عدد من النتائج مفادها وجود مستوى متوسط من درجة ممارسة القيادة الابتكارية لدى مديري مدارس لواء وادي السير، كما أشارت النتائج إلى وجود مستوى متوسط من جودة الأداء المدرسي لمديري مدارس لواء وادي السير، وأظهرت النتائج وجود علاقة ارتباطية ذات دلالة إحصائية بين القيادة الابتكارية بمجالاتها وجودة الأداء المدرسي لمديري مدارس لواء وادي السير وقد أوصت الدراسة بعقد دورات للتدريب على استراتيجيات حديثة تمكن مديري المدارس من التعامل مع الأفكار الابتكارية الجديدة، وعقد دورات تدريبية لمديري المدارس لزيادة معرفتهم بأساليب القيادة الابتكارية ليتمكنوا من التنبؤ بالمشكلات قبل حدوثها.
الكلمات المفتاحية: القيادة الابتكارية، جودة الأداء المدرسين ،المعلمين.
Bir Alman Subayının Gözünden Osmanlı Askeri Eğitimi; Goltz Paşa ve Arazi Eğitimi ile İlgili Görüşleri
Authors: ŞİMŞEKER Somer Alp , SABANCI Zeynep
Published: September 2022

Bu çalışmada, 19. yüzyıl Osmanlı İmparatorluğu’nda askeri reformları yönetmek üzere görevlendirilen Colmar Von Der Goltz’un askeri talim ve terbiye hakkındaki görüşleri yeni askeri tarihçilik ve topyekûn harp kavramları içerisinde değerlendirilecektir. 19. Yüzyıl küresel bir değişimin simgesi olmuştur. Teknolojik gelişmeler, zorunlu askerlik sisteminin doğuşu, sevkiyat olanaklarının değişmesi gibi gelişmeler, siyaset-ordu-toplum gibi kavramların iç içe geçmesini sağlamış ve ordular olası bir topyekûn harp ihtimaline karşı düzenlenmeye başlamıştır. Osmanlı da tıpkı Avrupa Devletleri’nde olduğu gibi bu değişime tabî olmuştur. Colmar Von Goltz Paşa bu reformların yapılması hususunda önemli bir role sahiptir. Bu araştırma, 19. Yüzyılda oluşan dönüşümü ve topyekûn harp kavramının yansımalarını Osmanlı Ordusu’nda Goltz Paşa’nın tespit ettiği eksiklikler ve önerilerinde arayacaktır.
FETİHTEN SONRA KIBRIS’TA KURULAN İLK OSMANLI VAKIFLARI
Authors: ARMAĞAN Abdüllatif
Published: September 2022

1571’de Kıbrıs’ın fethinden sonra Osmanlıların adada kurmuş olduğu en önemli teşkilatlardan biri vakıf teşkilatı olmuştur. Osmanlı hâkimiyetine girmesi ve ardından Osmanlı idari kurumlarının tesis edilerek Kıbrıs Beylerbeyliğinin oluşturulması ve nihayet Anadolu’dan Türk-İslam ahalinin yerleştirilmesiyle Kıbrıs, klasik bir Osmanlı toprağı kimliğini kazanmış ve adada ilk vakıflar kurulmaya başlanmıştır. Fetihten hemen sonra adada Osmanlı vakıf düzeninin oluşması için her türlü ortam hazırlanmıştı. Nitekim 1572’de Sultan II. Selim tarafından ilk vakıf kurulduktan sonra adaya atanan yüksek rütbeli asker ve yöneticiler de vakıf faaliyetlerine girişmişlerdir.

Kıbrıs’ta kurulan ilk Osmanlı vakıflarının en önemlileri arasında Sultan II. Selim Vakfı (1572), Kıbrıs Fatihi Lala Mustafa Paşa Vakfı (11 Mayıs 1579), Kıbrıs Beylerbeyi Kaptan-ı Derya Cafer Paşa bin Abdülmennan vakıfları (17 Ocak 1590, 2 Ağustos 1599, 4 Ocak 1602 ve 27 Mayıs 1607) ile sâbık Baf Sancakbeyi Mehmet Bey bin Ebubekir Vakfı (7 Kasım 1592) gibi vakıflar yer almaktadır. Fetihten sonra ilk planda yapılan vakıflar, Ebussuud Efendi’nin de ifade ettiği gibi, cihada katılarak şehit olanların geride kalan ailelerine, gazilere ve fethedilen yerlerin imarında sarf edilmek üzere kurulmuştur.

Vakfiye ve diğer arşiv belgelerine dayanılarak hazırlanan bu çalışmada, fetihten sonra Kıbrıs’ta görev yapan Osmanlı asker ve yöneticileri tarafından adada kurulan ilk Osmanlı vakıflarına ilişkin bilgi ve değerlendirmelere yer verilmiş ve fetihten sonra adada kurulan bu vakıfların adanın imar ve iskânı ile dini, sosyo-ekonomik ve kültürel hayatına etkileri üzerinde durularak Kıbrıs’ın Türkleşmesindeki rolü ve katkılarına değinilmiştir.
Geç Osmanlı Döneminde Ankara Basını
Authors: EROĞLU Ferhat
Published: September 2022

Osmanlı Devleti'nde eyalet sisteminden vilayet sistemine geçişle birlikte devletin merkezileşme hamlelerinin bir uzantısı olarak doğan vilayet gazeteleri, merkez dışı basının -taşra basınının- ortaya çıkmasına önayak olmuştur. Ankara'da Heyet-i Temsiliye'nin şehre gelmesinden kısa bir süre önce yayınlanan Mefkûre ve Selamet'in kökleri de devletin vilayet gazeteleri çıkararak sesinin taşrada yankılanması isteğinin bir uzantısı olarak doğan Ankara vilayet gazetesindedir. Fakat Ankara basını söz konusu olduğunda Heyet-i Temsiliye'nin bir milat yarattığının altını çizmek gerekir. Heyet-i Temsiliye öncesi Ankara basını ile sonrası Ankara basını birbirinden çok farklıdır. Bu durum hem zaman içinde etkisi hissedilen merkezin Ankara'ya taşınması eğilimiyle hem de Heyet-i Temsiliye'nin gelişinin Ankara gündemini değiştirmesi ile ilgilidir. Heyet-i Temsiliye ile birlikte Ankara'nın gündemi taşralılık ve yerellikten öte ulusallıktır. Artık söz konusu olan İstanbul'un belirleyiciliğiyle refleks gösteren bir basın değil belirleyicilik çabası ağır basan bir basındır. Bu nedenle Ankara basınının, Heyet-i Temsiliye merkeze alınarak, öncesi ve sonrasıyla ayrı ayrı incelenmesi gerekir.
KADROCULAR VE AHMET AĞAOĞLU TARTIŞMALARI
Authors: TÜRKİSLAMOĞLU Elif
Published: September 2022

Türk düşünce dünyasının önemli yayın hareketlerinden biri olarak 1932-1934 yılları arasında faaliyetlerini sürdürmüş olan Kadro dergisi yazarları ile hem Türkçülük hem de Türkiye’de liberalizmin öncü isimlerinden biri olan Ahmet Ağaoğlu arasında gazete yazıları üzerinden yapılan tartışmalar genç Cumhuriyet’in kalkınmasının hangi ilkeler etrafında olması gerektiği üzerine dikkate değer bir fikri mücadele niteliğindedir. Tartışma esas olarak Şevket Süreyya Aydemir’in 1932’de yayımlanan ve Kadro hareketine zemin teşkil eden düşüncelerinin yer aldığı İnkılâp ve Kadro (1932) kitabına ilişkin olarak Ahmet Ağaoğlu’nun Cumhuriyet gazetesinde yaptığı yorumları üzerine başlamıştır. Bu yazılara karşılık olarak yine aynı gazetede Şevket Süreyya Aydemir’in cevabi yazıları yayımlanmıştır. Sonrasında iki düşünürün yeniden cevap vermesiyle devam eden tartışmaya Yakup Kadri Karaosmanoğlu da 1933 yılı başlarında Vakit gazetesinde yazılarıyla dahil olmuştur. Bu çalışmada Ahmet Ağaoğlu ve Kadrocular arasındaki tartışmanın düşünsel yönleri üzerinde durulmaya çalışacaktır. Böylelikle Cumhuriyet’in kuruluşunun onuncu yılına doğru meydana gelen tartışma çerçevesinde Türk inkılabının nasıl yol alması gerektiği, özellikle toplumsal ve ekonomik kalkınmanın hangi ilkeler etrafında gerçekleştirilmesi konularında devrin önde gelen iki farklı düşünce odağının yaklaşımlarına ilişkin bir çıkarsama yapılması amaçlanmaktadır. Bu doğrultuda önce Kadro hareketi ve Ahmet Ağaoğlu hakkında kısaca bilgi verilecek, ardından gazete yazılarına ve Kadro dergisine yansıyan tartışma metinleri ele alınacaktır.
Optimización para la cría de Tecia solanivora (Povolný, 1973) (Lepidoptera: Gelechiidae) en condiciones de laboratorio
Authors: Pinzón-Rangel Diana Lizeth , Santos-Díaz Adriana Marcela , Numa-Vergel Stephanie Johana
Published: September 2022

La polilla guatemalteca Tecia solanivora (Povolný), es una de las principales plagas del cultivo de papa que afecta los rendimientos en campo y en condiciones de almacenamiento. Para su manejo, se han desarrollado diferentes estrategias como el uso de plaguicidas de síntesis química, control biológico, etológico y cultural. Para el desarrollo de investigaciones enfocadas en las estrategias de manejo mencionadas, es necesario contar con una cría de insectos que permita el suministro constante de individuos (adultos, huevos, larvas) con características geno y fenotípicas similares para asegurar la ejecución de los ensayos y la validez de los resultados. Actualmente, se cuenta con una cría de T. solanivora a mediana escala en condiciones de laboratorio con un protocolo de cría estandarizado, sin embargo, se requiere optimizar los criterios de producción de huevos y adultos, con el fin de disminuir los costos de producción. Para la optimización en la producción de huevos, se evaluaron dos tratamientos (50 y 70 adultos), y tres tratamientos para evaluar la producción de adultos a partir de cámaras de desarrollo de los estados inmaduros del insecto (3500, 4500, 5500 huevos). Se estableció que el tiempo máximo de recolección de huevos es de 5,15 días, no encontrando diferencias entre las dos densidades evaluadas. Para la producción de adultos se evidenció una relación directamente proporcional, a medida que aumenta la densidad de huevos se incrementa la producción de adultos en un orden 500 adultos por cada 1000 huevos viables. La optimización de estos parámetros permitió la disminución de mano de obra e insumos en el proceso de producción del insecto, sin afectar las características actuales de la cría.