bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of urination in alleviating man’s urethral pain associated with flexible cystoscopy: a single-center randomized trial
Authors: Xie Yingwei , Wang Wei , Yan Wei , Liu Dan , Liu Yuexin
Published: January 2020

Background

This study aimed to assess whether urethral pain can be alleviated by urination in male patients undergoing flexible cystoscopy.

Methods

Ninety-six male outpatients undergoing flexible cystoscopy were randomly divided into two groups. Patients in the test group urinated during flexible cystoscopy, whilst patients in the control group received no instructions to do so. All patients received 10 mL of 2% lidocaine gel prior to assessment. Using 0 (no-pain) to 10 (unbearable severe pain) pain scores (VAS), we assessed patient discomfort prior to anesthesia gel perfusion (baseline), during gel perfusion, during cystoscope insertion through the urethra, and 15 min post-examination analysis. The entire protocol was completed by a single doctor in our Department of Urology.

Results

The groups showed no statistical differences regarding age or examination time. During cystoscope insertion, the test group recorded significantly lower pain scores 2 (IQR 1–3) - compared to the control group 3 (IQR 2–3), (P = 0.001). No significant differences between other evaluation points were observed between groups.

Conclusion

Urethral pain can be significantly alleviated by urination in male patients undergoing flexible cystoscopy through the urethra.

Trial registration

Registry name: Clinical study of urination action to relieve urethral pain associated with flexible cystoscopy.

Registration number:ChiCTR-INR-17013294

Date of Registration: 2017-11-08
Impact of metabolically healthy obesity on the risk of incident gastric cancer: a population-based cohort study
Authors: Hashimoto Yoshitaka , Hamaguchi Masahide , Obora Akihiro , Kojima Takao , Fukui Michiaki
Published: January 2020

Background

The risk of colon or breast cancer in metabolically healthy obese (MHO) were lower than that in metabolically abnormal obese (MAO). We hypothesized that the risk of incident gastric cancer in MHO is lower than that in MAO.

Methods

This historical cohort study included 19,685 Japanese individuals who received health-checkup programs from 2003 to 2016. Each subject was classified as metabolically healthy (MH) (no metabolic abnormalities) or metabolically abnormal (MA) (one or more metabolic abnormalities), according to four metabolic factors (hypertension, impaired fasting glucose, hypertriglyceridemia and low HDL-cholesterol). Obese (O) or non-obese (NO) was classified by a BMI cutoff of 25.0 kg/m2. Hazard ratios of metabolic phenotypes for incident gastric cancer were calculated by the Cox proportional hazard model with adjustments for age, sex, alcohol consumption, smoking and exercise.

Results

Over the median follow-up period of 5.5 (2.9–9.4) years, incident rate of gastric cancer was 0.65 per 1000 persons-years. Incident rate of MHNO, MHO, MANO and MAO were 0.33, 0.25, 0.80 and 1.21 per 1000 persons-years, respectively. Compared with MHNO, the adjusted hazard ratios for development of gastric cancer were 0.69 (95% CI 0.04–3.39, p = 0.723) in MHO, 1.16 (95% CI 0.63–2.12, p = 0.636) in MANO and 2.09 (95% CI 1.10–3.97, p = 0.024) in MAO.

Conclusions

This study shows that individuals with MAO, but not those with MHO, had an elevated risk for incident gastric cancer. Thus, we should focus more on the presence of metabolic abnormalities rather than obesity itself for incident gastric cancer.
Comparison of clear cell carcinoma and benign endometriosis in episiotomy scar - two cases report and literature review
Authors: Xu Song , Wang Wei , Sun Li Ping
Published: January 2020

Background

Malignant endometriosis in an episiotomy scar is rare; only seven cases have been reported previously. Here, we compare two cases of benign endometriosis and clear cell carcinoma.

Case presentation

The first case was a 54-year-old woman who presented with a large perineal lesion in her episiotomy scar with high 18F-fluorodeoxyglucose uptake. This location had a history of endometriosis many years ago. She underwent radical excision of the mass and bilateral inguinal lymph node dissection. Histological and immunohistochemical analysis confirmed the presence of clear cell carcinoma arising from endometriosis. Assisted radiotherapy was performed after surgery due to a positive lymph node. No recurrence was detected over a 1-year follow-up period. The second case deals with a 3 × 2 cm mass in the episiotomy scar of a 33-year-old woman. Part of the anal sphincter was resected because of the close proximity of the lesion. Because the disease lay very close to the anus, she received anal sphincter reconstruction combined with mass excision. Pathology result showed typical endometrial glands and interstitial tissues.

Conclusions

Deleterious change only happens in patients experiencing perineal endometriosis. Complete excision is crucial for this form of disease; sometimes impairment of the anal sphincter is also necessary. Patients with malignancy required a combination of treatments in order to improve their prognosis.
Errors in estimated gestational ages reduce the likelihood of health facility deliveries: results from an observational cohort study in Zanzibar
Authors: Fulcher Isabel , Hedt Kaya , Marealle Stella , Tibaijuka Jalia , Abdalla Omar , Hofmann Rachel , Layer Erica , Mitchell Marc , Hedt-Gauthier Bethany
Published: January 2020

Background

Most maternal health programs in low- and middle- income countries estimate gestational age to provide appropriate antenatal care at the correct times throughout the pregnancy. Although various gestational dating methods have been validated in research studies, the performance of these methods has not been evaluated on a larger scale, such as within health systems. The objective of this research was to investigate the magnitude and impact of errors in estimated delivery dates on health facility delivery among women enrolled in a maternal health program in Zanzibar.

Methods

This study included 4225 women who were enrolled in the Safer Deliveries program and delivered before May 31, 2017. The exposure of interest was error in estimated delivery date categorized as: severe overestimate, when estimated delivery date (EDD) was 36 days or more after the actual delivery date (ADD); moderate overestimate, when EDD was 15 to 35 days after ADD; accurate, when EDD was 6 days before to 14 days after ADD; and underestimate, when EDD was 7 days or more before ADD. We used Chi-squared tests to identify factors associated with errors in estimated delivery dates. We performed logistic regression to assess the impact of errors in estimated delivery dates on health facility delivery adjusting for age, district of residence, HIV status, and occurrence of past home delivery.

Results

In our data, 28% of the estimated delivery dates were a severe overestimate, 23% moderate overestimate, 41% accurate, and 8% underestimate. Compared to women with an accurate delivery date, women with a moderate or severe overestimate were significantly less likely to deliver in a health facility (OR = 0.71, 95% CI: [0.59, 0.86]; OR = 0.74, 95% CI: [0.61, 0.91]). When adjusting for multiple confounders, women with moderate overestimates were significantly less likely to deliver in a health facility (AOR = 0.76, 95% CI: [0.61, 0.93]); the result moved slightly towards null for women with severe overestimates (AOR = 0.84, 95% CI: [0.69, 1.03]).

Conclusions

The overestimation of women’s EDDs reduces the likelihood of health facility delivery. To address this, maternal health programs should improve estimation of EDD or attempt to curb the effect of these errors within their programs.
Using the WHO-AIMS to inform development of mental health systems: the case study of Makueni County, Kenya
Authors: Mutiso Victoria N. , Musyimi Christine W. , Gitonga Isaiah , Tele Albert , Pervez Romaisa , Rebello Tahilia J. , Pike Kathleen M. , Ndetei David M.
Published: January 2020

Background

In order to develop a context appropriate in mental health system, there is a need to document relevant existing resources and practices with a view of identifying existing gaps, challenges and opportunities at baseline for purposes of future monitoring and evaluation of emerging systems. The World Health Organization Assessments Instrument for Mental Health Systems (WHO-AIMS) was developed as a suitable tool for this purpose. Our overall objective of this study, around which research questions and specific aims were formulated, was to establish a baseline on mental health system as at the time of the study, at Makueni County in Kenya, using the WHO-AIMS.

Methods

To achieve our overall objective, answer our research questions and achieve specific aims, we conducted a mixed methods approach in which we did an audit of DHIS records and county official records, and conducted qualitative interviews with the various officers to establish the fidelity of the data according to their views. The records data was processed via the prescribed WHO-Aims 2.2 excel spreadsheet while the qualitative data was analyzed thematically. This was guided by the six domains stipulated in the WHO AIMS.

Results

We found that at the time point of the study, there were no operational governance, policy or administrative structures specific to mental health, despite recognition by the County Government of the importance of mental health. The identified interviewees and policy makers were cooperative and participatory in identifying the gaps, barriers and potential solutions to those barriers. The main barriers and gaps were human and financial resources and low prioritization of mental health in comparison to physical conditions. The solutions lay in bridging of the gaps and addressing the barriers.

Conclusion

There is a need to address the identified gaps and barriers and follow up on solutions suggested at the time of the study, if a functional mental health system is to be achieved at Makueni County.
Fabrication and characterization of PLGA nanoparticles encapsulating large CRISPR–Cas9 plasmid
Authors: Jo Ami , Ringel-Scaia Veronica M. , McDaniel Dylan K. , Thomas Cassidy A. , Zhang Rui , Riffle Judy S. , Allen Irving C. , Davis Richey M.
Published: January 2020

Background

The clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of the utility of CRISPR–Cas9 for in vivo gene editing, a principal problem in implementing this new process is delivery of high molecular weight DNA into cells.

Results

Using poly(lactic-co-glycolic acid) (PLGA), a nanoparticle carrier was designed to deliver a model CRISPR–Cas9 plasmid into primary bone marrow derived macrophages. The engineered PLGA-based carriers were approximately 160 nm and fluorescently labeled by encapsulation of the fluorophore 6,13-bis(triisopropylsilylethynyl) pentacene (TIPS pentacene). An amine-end capped PLGA encapsulated 1.6 wt% DNA, with an encapsulation efficiency of 80%. Release studies revealed that most of the DNA was released within the first 24 h and corresponded to ~ 2–3 plasmid copies released per nanoparticle. In vitro experiments conducted with murine bone marrow derived macrophages demonstrated that after 24 h of treatment with the PLGA-encapsulated CRISPR plasmids, the majority of cells were positive for TIPS pentacene and the protein Cas9 was detectable within the cells.

Conclusions

In this work, plasmids for the CRISPR–Cas9 system were encapsulated in nanoparticles comprised of PLGA and were shown to induce expression of bacterial Cas9 in murine bone marrow derived macrophages in vitro. These results suggest that this nanoparticle-based plasmid delivery method can be effective for future in vivo applications of the CRISPR–Cas9 system.
The effect of a single spinal manipulation on cardiovascular autonomic activity and the relationship to pressure pain threshold: a randomized, cross-over, sham-controlled trial
Authors: Picchiottino Mathieu , Honoré Margaux , Leboeuf-Yde Charlotte , Gagey Olivier , Cottin François , Hallman David M.
Published: January 2020

Background

The autonomic nervous system interacts with the pain system. Knowledge on the effects of high velocity low amplitude spinal manipulations (SM) on autonomic activity and experimentally induced pain is limited. In particular, the effects of SM on autonomic activity and pain beyond the immediate post intervention period as well as the relationship between these two outcomes are understudied. Thus, new research is needed to provide further insight on this issue.

Objectives

The aim was to assess the effect of a single SM (i.e. SM vs. sham) on cardiovascular autonomic activity. Also, we assessed the relationship between cardiovascular autonomic activity and level of pain threshold after the interventions.

Method

We conducted a randomized, cross-over, sham-controlled trial on healthy first-year chiropractic students comprising two experimental sessions separated by 48 h. During each session, subjects received, in a random order, either a thoracic SM or a sham manipulation. Cardiovascular autonomic activity was assessed using heart rate and systolic blood pressure variabilities. Pain sensitivity was assessed using pressure pain threshold. Measurements were performed at baseline and repeated three times (every 12 min) during the post intervention period. Participants and outcome assessors were blinded. The effect of the SM was tested with linear mixed models. The relationship between autonomic outcomes and pressure pain threshold was tested with bivariate correlations.

Results

Fifty-one participants were included, forty-one were finally analyzed. We found no statistically significant difference between SM and sham in cardiovascular autonomic activity post intervention. Similarly, we found no post-intervention relationship between cardiovascular autonomic activity and pressure pain threshold.

Conclusion

Our results suggest that a single SM of the thoracic spine has no specific effect on cardiovascular autonomic activity. Also, we found no relationship between cardiovascular autonomic activity and pressure pain threshold after the SM. Further experimental research should consider the use of several markers of autonomic activity and a more comprehensive pain assessment.

Trial registration

N°NCT03273868. Registered September 6, 2017.
On the existence of solutions for a pointwise defined multi-singular integro-differential equation with integral boundary condition
Authors: Talaee Mandana , Shabibi Mehdi , Gilani Alireza , Rezapour Shahram
Published: January 2020

It is important that we increase our ability for studying of complicate fractional integro-differential equation. In this paper, we investigates the existence of solutions for a pointwise defined multi-singular fractional differential equation under some integral boundary conditions. We provide an example to illustrate our main result.
Acute intermittent porphyria (AIP) in a patient with celiac disease
Authors: Nunnemann Sebastian , Uibel Christoph , Budig Petra , Mäurer Mathias
Published: January 2020

We present the case of an 18 year old Caucasian with known celiac disease, who suffered a severe first attack of acute intermittent porphyria (AIP) with neuropsychiatric symptoms, severe tetraparesis and respiratory insufficiency. Treatment with heme arginate and high-dose intravenous glucose and rigorous rehabilitation resulted in a slow but almost complete recovery of her motor symptoms. To our knowledge this is the first case of acute intermittent porphyria triggered by malnutrition in the context of celiac disease. It is remarkable that the patient showed a favourable outcome despite the severity of her initial symptoms. This case shows the importance of early and systematic symptomatic treatment in patients with severe neurologic manifestation of AIP.
On inertial navigation and attitude initialization in polar areas
Authors: Wu Yuanxin , He Chao , Liu Gang
Published: January 2020

Inertial navigation and attitude initialization in polar areas become a hot topic in recent years in the navigation community, as the widely-used navigation mechanization of the local level frame encounters the inherent singularity when the latitude approaches 90°. Great endeavors have been devoted to devising novel navigation mechanizations such as the grid or transversal frames. This paper highlights the fact that the common Earth-frame mechanization is sufficiently good to handle the singularity problem in polar areas. Simulation results are reported to demonstrate the singularity problem and the effectiveness of the Earth-frame mechanization.
Research on BeiDou anti-spoofing technology based on comprehensive radio determination satellite service
Authors: Wang Fei , Hu Caibo , Wu Shuang , Tao Yixue , Xu Yunxiang
Published: January 2020

The BeiDou system (BDS) plays a significant role in people’s lives, but its security is easily affected by spoofing attacks. The radio determination satellite service (RDSS) is a special service of BDS that provides two-way communication, positioning, and timing services independently of the traditional radio navigation satellite service (RNSS). It can additionally be combined with RNSS to provide a comprehensive RDSS (CRDSS) service. In RDSS, after receiving a signal from the master station, the user needs to send a response signal back to the master station through a satellite. Therefore, the RDSS signal is difficult to spoof. In this study, based on the security feature of RDSS signals, an anti-spoofing method based on CRDSS is proposed to detect and mitigate spoofing attacks, verifying the advantages of the BeiDou system over other satellite navigation systems.
ОСОБЕННОСТИ ПРЕПОДАВАНИЯ АНАТОМИИ И ФИЗИОЛОГИИ ЧЕЛОВЕКА ДЛЯ СТУДЕНТОВ, ОБУЧАЮЩИХСЯ ПО НАПРАВЛЕНИЮ «ФИЗИЧЕСКАЯ КУЛЬТУРА»
Authors: Pogonysheva Irina Aleksandrovna , Skorobogatova Olga Nikolaevna
Published: January 2020

В статье рассмотрены особенности преподавания анатомии и физиологии человека студентам, обучающимся по направлению «физическая культура». Преподавание анатомии и физиологии человека для будущих специалистов физической культуры и спорта имеет свои особенности, по сравнению с таковым для студентов медицинских вузов и биологических факультетов университетов. Рассматриваются традиционные и инновационные методы обучения в рамках дисциплин анатомия и физиология человека.
ИСПОЛЬЗОВАНИЕ ВИДЕОМАТЕРИАЛОВ НА ЗАНЯТИЯХ ПО ДАКТИЛОЛОГИИ И РУССКОМУ ЖЕСТОВОМУ ЯЗЫКУ
Authors: Fayzullina Elmira Foatovna , Ilyicheva Tatyana Evgenievna
Published: January 2020

В связи с принятием в 2012 году закона о статусе жестового языка к глухим людям и их языку проявили интерес те, кто сталкивается в своей работе с глухими гражданами. Сотрудников полиции, органов социальной защиты, медицинских работников и т.п. стали обучать жестовому языку на различных курсах. Однако возникло большое количество вопросов: чему обучать, как обучать, как перевести на жестовый язык многочисленные профессиональные термины? В статье рассматриваются возможности использования видеоматериалов как визуальной формы представления информации с целью повышения восприятия материала на курсах по обучению русскому жестовому языку сотрудников органов внутренних дел.
РОЛЬ ВЗАИМОДЕЙСТВИЯ СЕМЬИ И ДОШКОЛЬНОЙ ОБРАЗОВАТЕЛЬНОЙ ОРГАНИЗАЦИИ В РАЗВИТИИ САМОСТОЯТЕЛЬНОСТИ ДОШКОЛЬНИКОВ
Authors: Gogitsaeva Olga Uruzbekovna
Published: January 2020

За последнее время детская самостоятельность все чаще становится объектом внимания исследователей, преподавателей и педагогов. Проблеме самостоятельности посвящены работы Р.С. Буре, Т. Гуськова, В.Д. Иванов, И.С. Кон и др., рассматривающих самостоятельность как свойство личности, которое предполагает независимость, способность самостоятельно, без подсказки, принимать важные решения и проводить их в жизнь.Самостоятельность развивается не только в семье, но и в условиях ДОО. Эффективности формирования самостоятельности у детей старшего дошкольного возраста будут способствовать следующие педагогические условия: целенаправленное формирование самостоятельности в семье с учетом уровня развития этого качества у ребенка; сотрудничество ДОО и семьи с целью повышения уровня самостоятельности детей.В ходе нашей исследовательской работы нами были выявлены особенности взаимодействия семьи и дошкольной образовательной организации в условиях реализации ФГОС. Мы выяснили, что главной целью в сотрудничестве с родителями является профессиональная помощь в вопросах воспитания и образования. При взаимодействии ДОО и родителей решаются задачи: активное взаимодействие с родителями для изучения их семейного микроклимата; оказание теоретической и практической помощи; повышение общей культуры семьи и психолого-педагогической компетентности родителей; использование традиционных и нетрадиционных форм сотрудничества и творчества.Нами были изучены методы, приемы и средства развития самостоятельности старших дошкольников в дошкольной организации и в семье: игры, проектная и поисковая деятельность, соблюдение режима дня, наличие домашних обязанностей, система поощрения и т.д. Проанализировав самостоятельность как качество личности дошкольника, мы пришли к выводу, что самостоятельность – это независимость, способность и стремление человека совершать действия или поступки без помощи других.
ОБУЧЕНИЕ ОРИЕНТИРОВАНИЮ НА МЕСТНОСТИ НА УРОКАХ ГЕОГРАФИИ
Authors: Kuznetsova Elza Afanasievna
Published: January 2020

Статья посвящена исследованию уровня знаний обучающихся 5 классов о способах ориентирования. Предметом анализа выступили когнитивный, эмоционально-мотивационный и деятельностный компоненты обучения на уроках географии. Были определены уровни сформированности знаний учеников об ориентировании. Обучающимися экспериментальной и контрольной групп продемонстрирован в основном низкий уровень сформированности компонентов при изучении ориентирования. Но изучение эмоционально-мотивационного компонента показало заинтересованность в изучении данной темы. В контрольной группе качественные показатели выше по сравнению с экспериментальной группой на 8-24%.
POTATO PRODUCTIVITY DEPENDING ON THE METHOD OF APPLICATION OF GROWTH REGULATOR AND CALCULATED BACKGROUND OF MINERAL NUTRITION ON THE GRAY FOREST STEPPE SOIL OF MIDDLE VOLGA REGION
Authors: Vladimirov Vladimir , Mostyakova Antonina , Egorov Leonid , Agiev Filus
Published: January 2020

The reaction of the early ripening potato of Vineta variety to different methods of using growth regulators against the calculated background of mineral nutrition on the gray forest-steppe soil of middle Volga was studied. The effectiveness of processing planting tubers and foliar treatment of plants during their vegetation has been established. The experiments were carried out on the control without the introduction of NPK and on a fertilized background, designed to obtain a tuber crop of 40 tons per hectare. The studies were conducted on gray forest medium loam granulometric composition soil of “Zemlyaki” farm in Nizhnekamsk district of the Republic of Tatarstan. Field experiments were carried out in 2019 by employees of Plant Growing and Horticulture Department of Kazan State Agrarian University. The humus content in the arable layer of soil according to Tyurin is 3.35%, pH is 5.7, easily hydrolyzable nitrogen is 112 mg/kg of soil, mobile phosphorus is 156 mg/kg, exchange potassium is 136 mg/kg of soil, molybdenum is 0.07, copper is 0.52, boron - 0.7, zinc - 4.82 mg/kg. The effectiveness of the integrated use of growth regulators (treatment of planting tubers and foliar application of the drug during the growing season) has been established. The yield increase to control against the background without applying basic fertilizers amounted to 4.82 tons per hectare, and against the background of their application - 4.80 tons per hectare.
Archivos 2019: Bienvenido OJS, apuesta decidida por la calidad y la visibilidad editorial
Authors: Fontcuberta Laura , Delclós Jordi , García Guillermo , Martínez José Miguel , Ramada José María , Ronda Elena
Published: January 2020

Iniciamos esta nota editorial de 2019, con el anuncio de un cambio relevante para los lectores, los diferentes comités, los evaluadores y, claro está, los autores, de Archivos de prevención de Riesgos Laborales y es la adopción de la herramienta de gestión editorial de la revistas científicas Open Journal Systems (OJS). Se trata del sistema de gestión de publicaciones científicas más extendido internacionalmente. Esta plataforma, a la que se puede acceder desde este enlace http://archivosdeprevencion.eu/index.php/aprl/login, permite que los usuarios registrados tengan asignado un papel determinado en todo el proceso de gestión, desde el envío del manuscrito hasta la consulta de la gestión, a medida que se va produciendo, sin necesidad de utilizar el correo electrónico como hasta ahora. Así, pues, por ejemplo, los autores podrán conocer, en todo momento, el estado en que se encuentra la revisión de su manuscrito. También los revisores podrán utilizar esta plataforma para el envío y comunicación de sus evaluaciones. La adopción de esta herramienta de gestión responde, por una parte, a nuestra voluntad de adaptación a lo que exige el movimiento de acceso abierto a la ciencia y hacia el cual iniciamos nuestra andadura con la eliminación del acceso restringido a los contenidos científicos de la revista en 2016. También, por otra parte, es un paso más, hacía nuestro objetivo, de incrementar la visibilidad de la revista como requisito para facilitar su indización en nuevas bases de datos científicas…
Mind the gap: profesionalización y seguridad y salud en el sector de la construcción
Authors: Segarra Cañamares María
Published: January 2020

Entrevista con la Dra. Segarra Cañamares
ПРИДАНИЕ ОГНЕЗАЩИТНЫХ СВОЙСТВ ЦЕЛЛЮЛОЗНЫМ ТЕКСТИЛЬНЫМ МАТЕРИАЛАМ С ПРИМЕНЕНИЕМ ЗОЛЬ - ГЕЛЬ ТЕХНОЛОГИИ
Authors: Tausarova Bijamal Raimovna , Stasenko Anastasiya Yur'yevna
Published: January 2020

The article presents studies on the use of a new composition based on sodium silicate, urea and sodium hydrogen phosphate to impart fire-retardant properties to cellulosic textile materials. The influence of the concentration of the starting components, temperature, and heat treatment time on the flame retardant properties was studied. The change in the fire retardant properties of cotton fabric is given for three heat treatment modes: at 80, 90 and 100 °C. Compared to the initial fabric, the samples treated with a flame retardant have indicators of flame retardant properties. Untreated fabric with a size of 220×170 mm when tested for flammability at an ignition time of 15 s completely burns out in 60 s. In samples treated with a flame retardant, at an ignition time of 15 s, the smoldering time is practically reduced to zero. With an increase in the concentration of the flame retardant, and the temperature of the heat treatment, the loss of material strength, breaking load, and the appearance of the fabric change slightly. Using electron scanning microscopy and energy dispersive microanalysis, it was shown that pure cotton fabric contains 68.77% carbon and 31.22% oxygen; after modification, particles of sodium – 0.02%, phosphorus – 0.04% and potassium – 0.05% are formed on the surface of the treated fabric. distributed fairly unevenly. It has been shown that in cellulosic materials modified with compositions based on sodium silicate and urea, sodium hydrogen phosphate, flame retardant properties increase. The proposed composition provides the achievement of higher fire resistance. Processing can be carried out on standard equipment of finishing enterprises without the stage of high-temperature fixation of the drug.
COMPOSITION OF THE ESSENTIAL OIL OF ARTEMISIA SUBVISCOSA TURCZ. EX BESS
Authors: Tsybicova Sayana Zoriktoevna , Zhigzhitzhapova Svetlana Vasil'yevna , Randalova Tuyana Erdemovna , Radnaeva Larisa Dorzhiyevna
Published: January 2020

Artemisia subviscosa Turcz. Ex Bess. is an endemic species of the Baikal region. It grow on the territory of the Barguzinsky region of the Republic of Buryatia. Raw materials for the study were collected during the expedition work in 2016. By the method of hydrodistillation the essential oils from the aerial parts and individual organs (inflorescences, leaves, stems) of the A. subviscosa was extract. The greatest yield of essential oil is registered in flowers (0.7%). The composition was determined by chromatography-mass spectrometry on an Agilent Packard HP 6890 gas chromatograph with a quadrupole mass spectrometer (HP MSD 5973N) as a detector. More than 70 components have been identified and it has been established that the composition of essential oils is represented by mono- and sesquiterpene compounds, the first predominantly accumulate in the inflorescences, the others – in leaves and stems and the aerial parts. The dominant components are santolina triene (2.9–33.1%), germacrene D (2.1–8.8%), β-selinene (6.4–9.3%), α-selinene (6.4–8.6%), α-bulnesene (1.9–2.7%), δ-cadinene (1.7–2.4%), caryophyllene oxide (2.1–9.9%), caryophyllene (11.6–17.5%), γ-muurolene (1.4–4.0%), aciphyllene (2.8–3.2%) , acyphyllic acid (4.5–10.5%), spathulenol (0.8–3.7%).
ACCUMULATION AND DISTRIBUTION OF BIOLOGICALLY ACTIVE SUBSTANCES IN RAW MATERIALS OF SOME TAXA OF THE GENUS PAEONIA L.
Authors: Reut Antonina Anatol'yevna , Denisova Svetlana Galimullovna , Pupykina Kira Aleksandrovna
Published: January 2020

The main purpose of the article was to study the content of the biochemical composition of different raw materials (flowers, leaves, stems, roots) of some representatives of the genus Paeonia L. (species ‒ P. peregrina Mill., P. officinalis L., P. lactiflora Pall., P. delavayi Franch., varieties ‒ Mechta S.P. Koroleva, Olga Kravchenko, Polyarnik 8, Sabantuy), introduced and grown on the basis of the South-Ural Botanical Garden-Institute of Ufa Federal Research Centre of Russian Academy of Sciences for further use as a new source of medicinal plant raw materials. The presence of amino acids was determined by the amino acid analyzer AAA-339 (HSSR), elemental composition ‒ by atomic absorption spectrometry. As a result of commodity analysis found that the leaves of paeony in maximum quantities accumulate ascorbic acid and starch; in the roots – sugar; in the stems – fiber; in flowers – carotenoids and protein. The study of the elemental composition of paeony showed that the P. peregrina quantitative content of calcium, phosphorus, iron, copper, manganese is superior to other types of peony; among the varieties, the maximum values of sodium, calcium, copper and iodine were noted in Olga Kravchenko. The presence of 14 amino acids, 9 of which are essential, was revealed. The maximum accumulation of amino acids is observed in the leaves of most species and in the stems of varieties of paeony. The amount of essential amino acids is 2.51–4.88 mg/%, the sum of all amino acids is 5.96–9.46 mg/%, which reflects the biological value of the objects of study.
FATTY ACIDS COMPOSITION AND PHYSICO-CHEMICAL CONSTANTS OF PUNICA GRANATUM L. SEED OIL
Authors: Zeynalova Aydan Mirza gyzy , Novruzov El'dar Novruz ogly
Published: January 2020

One of the important sources of essential fatty acids may be products of plant origin, in particular, oils extracted from seeds of wild and cultivated plants. One of these resources is wild-growing Punica granatum. The fatty acid composition of the lipid fractions of the seeds of wild-type pomegranate growing on the territory of Galalti, Siyazan region of the Azerbaijan Republic was assessed by gas chromatography after conversion to the methyl esters of the corresponding fatty acids. The highest oil yield – 12.92% was obtained by the extraction of the seeds at 60 °C for 8 h by Soxhlet extractor. Chromatographic analysis of the fatty oil of pomegranate seeds made it possible to establish the presence of 9 higher fatty acids. The main component of P. granatum seed oil was punicic acid (79.64%). Palmitic and stearic acids were found in small quantities. Content of these fatty acids were 3.29% and 2.43%, respectively. The least amount is accounted for by the share of myristic (0.03%) and heptadecanoic acids (0.03%).The analyses of physico-chemical constants and organoleptic properties of seed oil of P. granatum L. shows that the saponification numbers of wild-type pomegranate was 192.91 that indicates higher solubility of soap in water that can be made from it. The percentage of free fatty acids in our sample was 0.20% and the peroxide value – 3.03. The obtained results allow to consider the seed oil of this plant as good dietary fatty acid source. Thus, this study can provide valuable information for medicine and food industry for the development of drugs and food additives based on Azerbaijan wild-type pomegranate seed oil.
PRIMARY AND SECONDARY METABOLITES LASALLIA PENSYLVANICA
Authors: Sleptsov Igor' Vital'yevich , Prokopiev Il'ya Andreyevich , Zhuravskaya Alla Nikolayevna
Published: January 2020

Gyrophoric acid was isolated from thalluses of Lasallia pensylvanica and identification using IR, UV, MS spectrometry and differential scanning calorimetry. It was established that the content of gyrophoric acid in the lichen was 36 mg/g. It was shown that the gyrophoric acid exhibited antioxidant activity relative to the superoxide anion, NO, DPPH and ABTS radicals, inhibited the lipid peroxidation and reduced Fe (II) ions. At the same time, the antiradical activity of the gyrophoric acid relative to the superoxide anion and nitric oxide was higher by 1.3 and 1.6 times, respectively, compared with taxifolin. Neutral lipids, glycolipids, phospholipids and a fraction of water-soluble polysaccharides were isolated from the thalluses of Lasallia pensylvanica. It was shown that the main lipid fractions are neutral and phospholipids, the content of which were 84.25 and 73.25 mg/g, respectively. The yield of the fraction of water-soluble polysaccharides from the thalluses of Lasallia pensylvanica was 45.98%. It is established that the main monomers of the water-soluble fraction of the polysaccharide Lasallia pensylvanica are glucose and mannose. The study of the composition and content of low molecular weight compounds in the thalluses of Lasallia pensylvanica, performing the function of cryo- and osmoprotectants. Found compounds such as hydroxyproline, glutamine, arabitol, ribitol, mannitol, sucrose, trehalose.
COPMONENT COMPOSITION OF ROOT IN TWO SPECIES OPLOPANAX (ARALIACEAE)
Authors: Zhestovskaya Yelizaveta Sergeyevna , Vasilevskiy Sergey Valer'yevich , Aksenov Aleksey Vadimovich , Taranchenko Viktor Fedorovich , Stavrianidi Andrey Nikolayevich , Shpigun Oleg Alekseyevich
Published: January 2020

The qualitative and quantitative composition of two species of Oplopanax root was studied by gas chromatography with mass spectrometric detection. Extraction of components from the investigated objects was carried out by extraction of dry ground raw material with 70% ethanol. For the analysis of polar compounds, the extracts were further derivatized to give the corresponding trimethylsilyl derivatives. Identification of components was carried out using commercial (NIST17, Wiley14) and own custom mass-spectrometer libraries. The percentage of components found was calculated using the areas of the corresponding chromatographic peaks. Found in these samples were 130 compounds of various classes: terpenes and their derivatives, alcohols, aldehydes, polyyns, polyenes, various acids and their derivatives, phenols, sterols, lignans, vitamins, nucleosides, glycosides and sugars. It has been established that the qualitative and quantitative composition of root extracts varies even within the same species. The presence of 26 compounds common to the two species of Oplopanax, including 12 acids, 3 polyyns, 6 terpenes and one representative each from the class polyenes, aldehydes, lignans, glycosides and sterols, was revealed. As a result of the comparative analysis, it was established that 4 compounds from the class of polyyns (falcarindiol acetate, oplopanediol acetate, oplopantriol A and oplopantriol B) are found only in the roots of O. horridus.
PHYTOCHEMICAL STUDY OF THE HERB SANGUISORBA OFFICINALIS L. IN THE REPUBLIC OF BASHKORTO-STAN
Authors: Kazeeva Alina Ramilevna , Pupykina Kira Aleksandrovna , Denisova Svetlana Galimullovna , Shaydullina Galija Gaitnurovna , Reut Antonina Anatol'yevna
Published: January 2020

The main purpose of the work was the phytochemical study of the herb of the blood burnet drug (Sanguisorba officinalis L.) from six regions of the Republic of Bashkortostan and the rationale for the prospect of expanding its use in medicine. The collection of herbs was carried out in the flowering phase. The analysis of raw materials was carried out on the basis of the Bashkir State Medical University. Qualitative and quantitative determination of biologically active substances was carried out according to standard and modified methods. Amino acid composition was determined by x-ray fluorescence method The quantitative characteristics of the following groups of biologically active substances were determined: ascorbic acid (0.307–0.521%), organic (1.46–2.27%) and hydroxycinnamic (1.13–1.30%) acids, carotenoids (31.17–35.89 mg%), polysaccharides (0.43–1.05%), saponins (0.56–0.88%), coumarins (0.285–0.326%), tannins (5.1–6.3%). A characteristic of the amino acid composition. The possibility of using the herb of burnet drug is shown along with the rhizomes and roots, which will solve the problem of waste-free processing of this plant.
ANTIRADICAL ACTIVITY OF EXTRACTS FROM SIBERIAN FLORA GENUS CENTAUREA PLANTS
Authors: Kaminskiy Il'ya Petrovich , Yermilova Yelena Vasil'yevna , Kadyrova Tat'yana Vladimirovna , Lar'kina Mariya Sergeyevna , D'yakonov Anton Aleksandrovich , Belousov Mikhail Valer'yevich
Published: January 2020

The purpose of this research is to study the antiradical activity of various extracts from the Centaurea scabiosa L. aerial part (wild-growing and cultivated) and Centaurea jacea L. as potential sources of antioxidant herbal remedies. In the study of the antiradical activity of extracts from the aerial part of Centaurea jacea L., Centaurea scabiosa L. wild growing and cultivated, in the reaction with a stable diphenylpicrylhydrazyl radical, it was found that the degree of antiradical activity within each species correlates with the quantitative content of flavonoids. Lower values ​​of the antiradical activity of cultivated Centaurea scabiosa L. extracts compared to wild growing Centaurea scabiosa L. extracts are consistent with a lower content of flavonoids in the latter. The dependence of the Centaurea jacea L. and wild growing Centaurea scabiosa L. extracts antiradical activity on flavonoids quantitative and qualitative composition of these species has been established.
THE EFFECT OF PURIFIED AMOUNT OF TRITERPENE GLYCOSIDES AND THEIR ENRICHED EXTRACT FROM LEAVES OF SILPHIUM PERFOLIATUM L. ON THE GROWTH AND ACTIVITY OF NITRATE REDUCTASE OF WIN-TER WHEAT PLANTS
Authors: Davidyants Eleonora Sergeyevna
Published: January 2020

The effect of seed treatment with solutions of a purified amount of triterpene glycosides (PATG) containing, as major components, oleanolic acid glycosides – sylphiosides B, C, E, G, and extract (E) enriched with sylphiosides, from Silphium perfoliatum L. (Asteraceae) leaves on growth parameters and nitrate reductase activity (NR, EC 1.6.6.1) of 7-day winter wheat plants (Tritium aestivum L.) was studied. It was shown that, seed treatment with PATG solutions in concentrations of 0.0005 and 0.001% and E in concentrations of 0.2 and 0.4% caused an increase in the length of roots, shoots, wet and dry weight of seedlings compared to the control. The stimulating effect of these concentrations of PATG and E on the total nitrate reductase activity of the roots and leaves of seedlings has been established, and an increase in the stimulating effect of preparations on the activity NR оf against the background of substrate activation of the enzyme potassium nitrate (KNO3) was observed. The greatest increase in the total NR activity of roots and leaves of winter wheat plants was observed when PATG acted at a concentration of 0.001% and E – at a concentration of 0.4%, which amounted respectively 122 and 116%, when adding 1 ml of 50 mM KNO3 solution into the growing medium of plants – 141 and 137% relative to the control. The stimulating effect of exogenous triterpene glycosides on NR activity has been established for the first time. The obtained data allow to theoretically substantiate the possibility of practical use of triterpene glycosides and preparations based on them for the regulation of growth and nitrogen metabolism of plants.
The Use of Coffee Husk as Napier Grass Substitution and Its Effect on Madura Cattle Performance
Authors: Sudarman Asep , Listiawan G B , Khodijah L
Published: January 2020

This research aimed to evaluate the performance of fattened madura cattle fed on coffee husk as a source of fibre to substitute grasses. Twenty Madura steers aged approximately 1.5 to 2.0 years with initial weight of 165-190 kg were divided randomly into four different experimental diets, namely R0= 90% concentrates +0% coffee husk +10% napier grass, R1= 90 % concentrates +3.33% coffee husk +6.67% napier grass, R2 = 90% concentrate +10% 6.67% coffee husk +3.33% napier grass, R3 = 90% concentrates 90% + 10% coffee husk +0% napier grass. The feed was given at 3% body weight of dry mater. The cows were kept in individual pen for two months. Variables measured were dry mater intake, feed efficiency, average daily gain (ADG), digestibility of feed and income over feed cost. Data obtained were analyzed using analysis of variance based on randomized block design followed by Duncan’s multiple range test. Results showed that dry matter intake, ADG, feed efficiency and feed digestibility of cattle on each treatment of the feed were not significantly different (P > 0.05). Average of dry matter intake and daily gain for R0, R1, R2, and R3 were 6.01, 5.84, 5.73 and 5.62 kg/head/day and 0.88, 0.87, 0.84 and 0.93 kg/head/day respectively. While the average of feed efficiency and DM digestibility for R0, R1, R2, and R3 were 14.64, 14.89, 14.65 and 16.54 % and 84.82, 84.37, 83.47 and 83.30 %, respectively. It is concluded that the used of 10% coffee husk as a source of fibre for substitution of napier grass can be used without negative effect on madura’s cattle performances and tend to give higher values of IOFC on fattening program.
Numéro 155 - janvier 2020
Authors: Attanasi Gautier , Bodart Vincent , Courtoy François , Fontenay Sébastien , Lachapelle Nathan , Ounnas Alexandre , Sauvenier Mathieu
Published: January 2020

Malgré un environnement économique international affaibli, l’économie belge a progressé de 1,3 % en 2019. Cette expansion demeure néanmoins modeste et plus faible qu’en 2018. La croissance de l’économie belge resterait timide en 2020. L’environnement économique international demeure en effet perturbé par les tensions commerciales et par les conséquences économiques du Brexit. Au niveau belge, le sentiment de confiance des ménages et des entreprises reste faible. La progression du pouvoir d’achat serait par ailleurs nettement ralentie en 2020. La contribution de la demande intérieure à la croissance serait donc limitée en 2020.

En résumé, nos prévisions macroéconomiques pour 2020 sont les suivantes :

• L’économie belge devrait croître de 1,3 % en 2020.• L’emploi augmenterait, en termes nets, de 44.300 unités en 2020.• Le nombre de demandeurs d’emploi diminuerait de 14.000 unités en 2020.• L’inflation générale des prix à la consommation s’élèverait à 1,4 % en 2020.• Le déficit budgétaire des administrations publiques s’élargirait à 2,3 % du PIB en 2020.
RESOURCE-INDEPENDENT REPRESENTATION OF SORTING NETWORKS IN Set@l PROGRAMMING LANGUAGE
Authors: Pisarenko I. V. , Alekseev K. N. , Melnikov A. K.
Published: January 2020

The development of scalable parallel programs for high-performance computer systems with reconfigurable and hybrid architectures is an important problem in the field of modern supercomputer engineering. Resource-independent applied software in the high-level COLAMO programming language describes only the limited number of the algorithm implementations for some configurations due to the inductive principle of the information graph forming. However, the creation of efficient resource-independent parallel software requires programming tool that supports both induction and reduction of calculations. To solve the problem, we propose the application of the Set@l programming language based on the aspect-oriented programming paradigm and set-theoretical code representation. According to the aspect-oriented concept, Set@l describes an algorithm for the problem solution and its parallelizing and other implementation features as separated program modules – source code and various aspects. The programming language being considered has much in common with traditional set-theory-based languages such as SETL, SETLX and SETL2, but Set@l introduces the essential classification of collections by parallelism, definiteness, orderliness and other criteria. In contrast to the high-level COLAMO programming language, Set@l specifies the full information graph of a computational problem in the absolutely parallel form and describes the reduction principles for all configurations of a computer system as independent aspects of a program. In this paper, we demonstrate that the aspect-oriented sorting program in the Set@l language defines different types of quadratic sorting networks and various methods of their partition and reduction.
Übersetzungsstrategien von Grimms Rotkäppchen am Beispiel polnischer Übersetzungen
Authors: EBERHARTER-AKSU MARGIT , HINC JOLANTA
Published: January 2020

The fairy tales of the Brothers Grimm belong to the best-known literary works of Germany, besides the Luther Bible. They are currently published in 160 languages and have been part of the World Documentary Heritage since June 2005. In Poland, they are known in countless translations, adaptations and retellings, some of which have been greatly modified and adapted for teaching purposes and others are literally based on the original texts. The empirical part of the article refers to an experiment in which 19 subjects were presented with a translation task: to transfer selected passages of Little Red Riding Hood into Polish. In the runup to the study, it was hypothesized that the information about the status of the work as part of the World Document Heritage given to study participants should have an effect on the literal translation. The results of the experiment do not confirm the assumed hypothesis, but clearly show that the translation variants above all have to be seen as a continuation of the individual’s experiences with the fairy tale, which strongly influences that individual’s translation
So-called dictionary equivalents confronted with parallel corpora (and the consequences for bilingual lexicography)
Authors: KUBICKA EMILIA
Published: January 2020

The study considers the question of whether (and how) bilingual dictionaries may be improved. The information presented in dictionaries has been confronted with textual reality (i.e., with examples of actual translations), based on the German expression fassungslos and its Polish equivalents in parallel texts. The author assumes that bilingual dictionaries are mainly used by language learners, while professional translators may consider them as one of many possible sources. In teaching, multiplying the possible equivalents or suggesting ad hoc solutions is generally not recommended. Despite the attempts at objectivizing lexicographic descriptions, which are made possible by using language corpora, it often turns out that the decisions made by dictionary authors are (and need to be) arbitrary