bluuebunny/crossref_metadata_2025 huggingface dataset:
NOVAS ESTRATÉGIAS NO TRATAMENTO DE INSUFICIÊNCIA CARDÍACA: REVISÃO INTEGRATIVA
Authors: Barros Eliab Batista , Ribeiro Claudia Holanda , Souza Vanessa Maria Gonçalves de , Pinto Icaro Rodrigues Mendes Pedrosa , Campelo Bruna Barbosa Fiuza , Moura Vytoria Rodrigues , Leôncio Plínio Viana , Barreto Alex Fabiano Sousa , Araújo Sâmia Moura , Carvalho Felipe Martins de
Published: September 2024

Introdução: A insuficiência cardíaca (IC) é uma condição clínica de alta prevalência, caracterizada pela incapacidade do coração em bombear sangue de forma eficiente, comprometendo o suprimento de oxigênio e nutrientes aos tecidos do corpo.
Metodologia: A metodologia adotada para a elaboração deste trabalho incluiu uma revisão integrativa da literatura científica recente sobre novas estratégias no tratamento da insuficiência cardíaca.
Resultado: Os resultados da revisão da literatura indicam que as novas estratégias no tratamento da insuficiência cardíaca têm trazido avanços significativos na melhoria da sobrevida e da qualidade de vida dos pacientes. As terapias farmacológicas, como os inibidores de SGLT2 e os ARNIs, emergem como pilares no manejo da IC, oferecendo benefícios que vão além da simples redução dos sintomas.
Conclusão: Em suma, a IC representa um dos maiores desafios para a medicina moderna, devido à sua alta prevalência, complexidade e impacto sobre a qualidade de vida dos pacientes.
ACNE E DIETA: ESTUDOS SOBRE A RELAÇÃO ENTRE ALIMENTAÇÃO E AGRAVAMENTO DA ACNE
Authors: Lima Mirella Maria , Leal Pires Santos Igor , Macedo de Oliveira Ingrid , Jéssica de Sousa Rosa , Brito Bezerra da Silva Roberta , Neto Alencar Cunha Leitão Joaquim , Queiroz Camelo João Victor , Ruben Pereira de Carvalho Eduardo , Mendes Lustosa Jennifer , Prata Chrisóstomo Neto Edson , Andrade Nogueira Ana Beatriz , De Moura Santos Pereira Ferraz Baptista Liège , Barboza de Andrade Mariana
Published: September 2024

Este artigo tem como objetivo realizar um estudo na literatura médica sobre a relação entre Acne e Dieta. A acne é uma condição de pele comum que ocorre quando os folículos pilosos ficam obstruídos por óleo (sebo) e células mortas, resultando em cravos, espinhas, e lesões inflamatórias. Fatores como hormônios, genética, estresse, e dieta podem contribuir para o seu desenvolvimento. A condição é mais comum durante a adolescência, mas pode afetar pessoas de todas as idades. Tratamentos incluem produtos tópicos, medicamentos orais, e cuidados com a pele. A dieta pode influenciar a acne, com estudos sugerindo que alimentos com alto índice glicêmico, laticínios e dietas ricas em açúcares e gorduras saturadas podem agravar a condição. Esses alimentos podem aumentar a produção de sebo e a inflamação, fatores que contribuem para a formação de acne. Por outro lado, uma dieta rica em alimentos anti-inflamatórios, como ômega-3 e antioxidantes, pode ajudar a melhorar a saúde da pele. Foram utilizados como motores de buscas os indexadores PubMed, Scopus, Web of Science, SciELO e google scholar para seleção dos artigos através dos unitermos.
AVANÇOS NA PREVENÇÃO E MANEJO DAS DOENÇAS CARDIOVASCULARES: PERSPECTIVAS ATUAIS
Authors: Santos Matheus Miranda dos , Rodrigues Natália Maisa de Souza , Rodrigues Bruno Matheus , Oliveira Daniel de Saboia , Andrade Monique Pereira de Oliveira de , Campos Rafael Vilela de , Filho Márcio Chagas Ribeiro , Gonçalves Paola Costa , Loubet Murillo Barbosa , Campos Gattass Carneiro Orro de , Rampanelli Gabriela
Published: September 2024

Este estudo revisou abordagens recentes e emergentes no tratamento das doenças cardiovasculares (DCVs), destacando os avanços significativos em diagnóstico, terapias farmacológicas e intervenções minimamente invasivas. A integração de tecnologias como inteligência artificial tem permitido uma maior precisão no diagnóstico e na personalização das intervenções, enquanto novos medicamentos, como inibidores do cotransportador de sódio-glicose tipo 2 (SGLT2) e moduladores de receptor de angiotensina-neprilisina (ARNI), têm melhorado os desfechos clínicos em pacientes com insuficiência cardíaca e outras DCVs. As técnicas de intervenção percutânea, incluindo substituição valvar aórtica transcateter (TAVI) e angioplastia coronariana, têm mostrado benefícios em termos de recuperação e qualidade de vida. Apesar dos avanços, os desafios persistem, particularmente na equidade de acesso às novas tecnologias e na sustentabilidade dos sistemas de saúde. A análise destacou a necessidade de uma abordagem holística que considere comorbidades e fatores socioeconômicos dos pacientes. Além disso, a pesquisa identificou lacunas em personalização de terapias e integração de cuidados multidisciplinares, apontando para futuras áreas de investigação, como o desenvolvimento de biomarcadores específicos e o uso de tecnologias de monitoramento remoto. Este estudo conclui que, embora a cardiologia esteja em um período de transformação promissor, é fundamental equilibrar a adoção de novas tecnologias com a manutenção de práticas baseadas em evidências para garantir o acesso equitativo e a eficácia dos cuidados. A continuidade da pesquisa e inovação é essencial para melhorar o manejo das DCVs e a qualidade de vida dos pacientes.
Predictors of 30-Day Hospital Readmission Following CABG in a Multicenter Database: A Cross-Sectional Study
Authors: Silva Rene Augusto Gonçalves e , Borgomoni Gabrielle Barbosa , de Freitas Fabiane Letícia , Maia Adnaldo da Silveira , Farias do Vale Junior Cleóstones , Pereira Eva da Silva , Silvestre Leonardy Guilherme Ibrahim , Dallan Luís Roberto Palma , Lisboa Luiz Augusto , Dallan Luís Alberto Oliveira , Jatene Fabio Biscegli , Mejia Omar Asdrúbal Vilca
Published: September 2024

Abstract Background: The analysis of indicators such as hospital readmission rates is crucial for improving the quality of services and management of hospital processes. Objectives: To identify the variables correlated with hospital readmission up to 30 days following coronary artery bypass grafting (CABG). Methods: Cross-sectional cohort study by REPLICCAR II database (N=3,392) from June 2017 to June 2019. Retrospectively, 150 patients were analyzed to identify factors associated with hospital readmission within 30 days post-CABG using univariate and multivariate logistic regression. Analysis was conducted using software R, with a significance level of 0.05 and 95% confidence intervals. Results: Out of 3,392 patients, 150 (4,42%0 were readmitted within 30 days post-discharge from CABG primarily due to infections (mediastinitis, surgical wounds, and sepsis) accounting for 52 cases (34.66%). Other causes included surgical complications (14/150, 9.33%) and pneumonia (13/150, 8.66%). The multivariate regression model identified an intercept (OR: 1.098, p<0.00001), sleep apnea (OR: 1.117, p=0.0165), cardiac arrhythmia (OR: 1.040, p=0.0712), and intra-aortic balloon pump use (OR: 1.068, p=0.0021) as predictors of the outcome, with an AUC of 0.70. Conclusion: 4.42% of patients were readmitted post-CABG, mainly due to infections. Factors such as sleep apnea (OR: 1.117, p=0.0165), cardiac arrhythmia (OR: 1.040, p=0.0712), and intra-aortic balloon pump use (OR: 1.068, p=0.0021) were predictors of readmission, with moderate risk discrimination (AUC: 0.70).
Sleep Duration and the Risk of Atherosclerosis: A Mendelian Randomization Study
Authors: Xu Xiaozhuo , Huang Yilin , Liu Jing , Han Xu
Published: September 2024

Abstract Background: The association between the length of sleep and atherosclerosis has been reported in many observational studies. However, little is known about its significance as a risk factor for atherosclerosis or as a negative consequence of atherosclerosis. Objective: This study aimed to assess the causal association between sleep duration and the risk of atherosclerosis using publicly available genome-wide association studies (GWAS) summary statistics. Methods: We employed a two-sample Mendelian randomization (MR) method with 2 cohorts from MRC-IEU (n=460,099) and UK Biobank (n=361,194) to investigate the causal association between sleep duration and the risk of atherosclerosis. Three methods including the inverse-variance weighted (IVW) technique, Robust adjusted profile score (RAPS), and simple-and weighted-median approach were used to obtain reliable results, and an odds ratio with a 95% confidence interval (CI) was calculated. P<0.05 was considered as a statistical difference. In addition, MR-Egger regression, Radial MR, MR-PRESSO, and leave-one-out analyses were used to assess the possible pleiotropy effects. Results: No causal association of sleep duration with atherosclerosis was found [OR (95%CI): 0.90 (0.98-1.00), p = 0.186]. Leave-one-out, MR-Egger, and MR-PRESSO analyses failed to detect horizontal pleiotropy. Conclusions: This MR analysis indicated no causal association between genetically predicted sleep duration and atherosclerosis across European populations.
Flipped learning in a molecular biology course: pre-service teachers’ performance and perceptions
Authors: Reinoso Tapia Roberto , Galindo Sara , Delgado-Iglesias Jaime , Bobo-Pinilla Javier
Published: September 2024

The aim of this research was to evaluate and compare the efficiency of the flipped learning strategy with that of a conventional teaching method with respect to learning outcomes, cognitive gain, and perception and satisfaction with regard to the methodology used. The research was carried out during the 2021-2022 academic year and focused on a molecular biology course within a primary education Bachelor's degree programme, which included a total of 146 students. In order to assess the students' comprehension of the mechanisms involved in DNA replication, transcription, and translation, we employed two different methods: the multiple-select Central Dogma Concept Inventory (CDCI) and a concept-mapping activity. A three-point Likert-type scale questionnaire was used to investigate the pre-service teachers' perceptions of the methodological approach that we used. The results show that the flipped learning pedagogical approach not only increases pre-service teachers' performance but also enables them to develop higher level cognitive skills than with traditional methodology. However, several features of the central dogma processes remained poorly understood, probably because of the multilevel and invisible nature of the molecular biology, and the lack of knowledge of the molecular interactions that facilitate these processes. The pre-service teachers had a more positive perception of the teaching approach and their own competence when they followed the flipped model.
Comparative morphology of the fabricium bursa of broiler chickens of the Smena-9 cross with different feeding diets
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Stepanishin Viktor V. , Posyabin Sergey V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Borkhunova Elena N. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Kondratov Gleb V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Antipov Alexander A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia
Published: September 2024

The article presents the results of a study of the effect of feed additives [7] on the morphological characteristics of fabricium bursa of broiler chickens of the Smena-9 cross at the age of 35 days. During the study, it was found that pronounced morphological changes in the structure of the fabrician bursa, and the general structure of the organ indicates the development of involution processes, which is more pronounced in animals of all experimental groups. The results obtained can be used as morphological criteria for quality control of poultry farming. Data on the structure of the fabricium bursa of the new domestic cross expand the theoretical base in the field of biology of farm birds, including in terms of identifying morphological signs of the realization of genetic potential against the background of the use of different feeding diets in chicken rearing technology, which allows us to quickly assess the effectiveness of chicken rearing technology and predict an increase in productivity.
Use of dried blood samples for serologic monitoring of avian salmonellosis
Authors:   Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary Science named after K. I. Skryabin and Y. R. Kovalenko of Russian Academy of Sciences (FSC VIEV RAS), Moscow, Russia, Ruzina Anna V.
Published: September 2024

Comparative studies of liquid serum and dried samples of whole blood of chickens obtained on absorbent membrane carriers in the form of strips to determine the titer of antibodies to S. enteritidis by ELISA method have been carried out. It was found that the results of analysis of dry whole blood samples correspond to the results of liquid serum studies.
The effect of bacteriocins on prolongation of shelf life and toxicological parameters of chilled meat
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Fabrikantova Elizabeth A. , Bachinskaya Valentina M. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Gonchar Dmitry V. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin”, Moscow, Russia, Alekseenkova Svetlana V. ,   All-Russian Institute of Experimental Veterinary Medicine of the Russian Academy of Sciences – VIEV RAS, Moscow, Russia
Published: September 2024

The presented article is devoted to the urgent problem of searching for natural food preservatives that can not only prolong the shelf life of products of animal origin, but also not cause undesirable effects in consumers that lead to health problems. This paper presents the results of physicochemical and toxicological studies of chilled pork and broiler meat treated with various concentrations of antimicrobial drugs of bacterial origin (Nizin and Natamycin). The research was carried out on the basis of the Federal State Budgetary Educational Institution of Higher Education MGAVMiB – MBA named after K. I. Scriabin and on the basis of the Federal State Budgetary Scientific Institution FSC VIEV RAS. To confirm the effect of Nisin and Natamycin on extending the shelf life of chilled meat, physicochemical and toxicological studies were carried out on samples of chilled pork and chilled chicken. Physicochemical studies of meat were carried out according to generally accepted methods. The cytotoxicity of bacteriocins was assessed (toxicological study) using monolayer cell lines (PT and SPEV). According to the results of physicochemical studies in samples treated with bacteriocins, there was a prolongation of the shelf life of chilled pork up to 15 days, chilled broiler meat – up to 10 days. When conducting a cytotoxicity test, no negative effect on monolayer cell lines was established these antimicrobial drugs are safe when dosages are observed.
Domestication transformations of intestinal length in American minks (Mustela vison Schreber, 1777)
Authors:   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Fedorova Oksana I. , Orlova Elena A. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation, Misharina Ekaterina I. ,   Moscow State Academy of Veterinary Medicine and Biotechnology – MVA by K. I. Skryabin, Moscow, Russian Federation
Published: September 2024

The article presents the results of measuring the body and intestinal length of minks caught in the wild and bred on fur farms. A comparative analysis of changes in these parameters in domesticated animals compared to wild ones is given. It was established that over the course of many years of mink breeding on farms, body length in females increased by 1,21–1,26 times, in males by 1,22–1,30 times. The length of the intestine increased by 1,20–1,26 times. The coefficients of variation for body length in farm minks were 3,1–4,9, and for intestinal length – 5,8–8,9 units.
Study of acute toxicity of the vitaminmineral feed additive «Active Mix» VM 10/20 on laboratory rats
Authors:   Udmurt State Agrarian University, Izhevsk, Russia, Kulikov Andrey N.
Published: September 2024

To compensate for the deficiency of vitamins and minerals in animals' bodies, various vitamin and mineral feed additives are introduced into their diet. They must be highly effective and safe for the body. When developing a new liquid vitamin and mineral feed additive «Active Mix» VM 10/20, the toxicological properties of its components were studied: «Active Mix» VM-10 and «Active Mix» VM-20 in experiments on white non-linear laboratory rats. The animals of the experimental groups were injected intragastrically with the help of a metal probe with the studied solutions, and the control group was injected with a 0,9 % NaCl solution. The survival rate of the rats, their general condition, water and food consumption, and response to stimuli were assessed. During the experiment, it was not possible to achieve lethal doses. All the animals survived. The maximum possible volume of a single injection of solutions for rats of a given age and weight was 5 ml. Further increase in the administered dose turned out to be inappropriate and impossible. The LD50 value (for rats) would certainly be higher than 5000 mg/kg. Liquids «Active Mix» VM-10 and «Active Mix» VM-20 should be classified as hazard class 4 according to GOST 12.1.007-76 i.e. to low-hazard substances.
A Study of the Awareness of Environmental Sanitation among Women
Authors: - B.R.Leelavathi , - P.Adinarayana Reddy
Published: September 2024

Environmental Sanitation promotes the health and wellbeing of the Humanity. It has many components, out of which the cleanliness, Health and Hygiene, drinking water and sewage and its disposal plays an important role in environmental sanitation. Promotion of environmental sanitation depends on the awareness possessed by the stakeholders and women in particular as they are directory involved in safeguarding it. In view of the above, the present study was conceived to understand the characteristics of self-help group women and to find out the awareness of the women in environmental sanitation in terms of cleanliness, hygiene, drinking water and sewage and its disposal. The study was conducted in the Ananthapuram District of Andhra Pradesh on a sample of 400 women. The investigator has designed a open ended schedule to identify the awareness of the women. The finding of the study revealed that the sample are represented form middle aged, Backward castes, married, low educated, with two children. The house hold head are male, married, low educated. The family background shows that more than half of the sample has 3-4 members in their family, middle income, nuclear families, wage earners, and have their own house with two rooms, half of the sample are aware of the purification of water and quantity of water to be taken per day. The knowledge in self-hygiene among the sample was found to be significant in case of utility of soap, cleaning of hands, best habits of bath etc. On the other hand, the sample does not have adequate knowledge in case of place and cleaning of hands, frequency of bath. The women are well aware about keeping the surrounding cleanly to avoid the bad smell and pollution, disposal of garbage, mosquito breeding due to storage of sewage, effect of sewage on village health, disposal of household garbage, keeping the lid on the solid waste storage pit, disposable of waste water to prevent the mosquitoes breeding etc. Hence there is a need to promote awareness among the community in the area where there is a need and should convert the awareness to healthy habits.
Balancing Innovation and Privacy: Assessing the Legal Implications of Artificial Intelligence in the Context of Privacy Rights and Data Protection
Authors: - PRATYUSH PRAKARSH , - MANSI , - HARSH VARDHAN
Published: September 2024

Artificial intelligence (AI) technologies have rapidly evolved and are increasingly integrated into various aspects of society, including commerce, healthcare, law enforcement, and governance. While AI offers numerous benefits, such as enhanced efficiency and decision-making capabilities, its widespread adoption raises significant concerns regarding privacy rights and data protection. This research paper examines the legal implications of AI in relation to privacy rights and data protection, focusing on the challenges of balancing innovation with the need to safeguard individual privacy. By analyzing relevant laws, regulations, and case studies, this paper explores the ethical, social, and legal considerations surrounding AI technologies and proposes strategies for achieving a harmonious balance between innovation and privacy.
Architecture as a Trigger for Socio-Economic Development
Authors: - Meghna Tushar Sutaria , - Rajesh Mehta
Published: September 2024

Settlements in rural India are socio-culturally unique. Their physical cluster based pattern, occupational pattern, cultural dimensions and economy set them apart from the rest of the world. But the most important parameter that keeps them distinct and grounded is their people and culture. Urban settlements in India are growing rapidly, diminishing the rural counterpart. Many villages are becoming part of Urban Agglomeration or are under heavy pressure of urbanization. It is without doubt that, cultural dimension of rural habitats is one of the major parameters for which our country is recognized worldwide.
Most of Indian rural and peri-urban areas have long-established craft clusters or communities which impact the livelihood of the residents. These crafts in many settlements were the second best employment generator after agriculture be it pottery, toy making or textiles. These craft communities are under transition due to changing times. Social cohesiveness of such settlements are also in danger due to migration and changing social dynamics. This impacted their settlement patterns adversely. These aspects needs urgent attention of policy makers and Indian rural areas are in dire need of rejuvenation.
Architecture or built environment plays an important role in creating an identity of an area. It also provides people the suitable platform or arena to perform their activities, social or occupational. Appropriate spaces with right mix of user centric activities creates excellent places to inhabit and thrive. Wisely designed architectural programs in underprivileged areas can trigger growth potential. Truly said by Winston Churchill, “we shape our buildings; thereafter they shape us.” This concept paper aims to investigate the power of right architecture as a trigger for socio-economic growth of a less focused area with the help of case studies and pre – post scenario analysis. The paper also discusses the tailored approach to design right architecture insert in such existing settlement so, that its inherent characteristics don’t get affected adversely as well as it doesn’t dilute its conventional cultural identity.
The Lindhard Theory of Screening to Study Effective Electron-Electron Interactions
Authors: - Umme Aqsa
Published: September 2024

This research Paper explores the application of the Lindhard theory of screening to study effective electron-electron interactions in various systems. The Lindhard theory, developed by Danish physicist Jens Lindhard , describes the screening of a test charge by a surrounding electron gas. By applying this theory, we can gain insights into the behavior of electrons in different environments and understand how they interact with each other. The Lindhard theory of screening provides a fundamental understanding of electron-electron interactions within a many body electron gas.
This paper explores the theoretical underpinnings of the Lindhard theory, its mathematical formulation, and its implications for effective electron electron interactions in metals. By examining the response of an electron gas to perturbations, the lindhard function is derived, and its impact on screening the coulomb interaction is analyzed. Applications in understanding the electrical and thermal properties of metals, as well as complex phenomena like superconductivity and plasmon excitations, are discussed
Cow Protection vis-a-vis the Constitution
Authors: - Kuvam Verma
Published: September 2024

Bans on cow slaughter or cow protection, whichever way one interprets it has become a controversial and sensitive issue in recent years. However, this has not been merely due to the change in power in New Delhi and in various states, while political power does have a significant role to play in formulation of stringent cow protection laws and the worrying rise of cow vigilantism, there is a constitutional basis to these actions and that basis is provided by Article 48 of the Constitution. In this research paper, I endeavour to trace the history of cow protection in this country and how that culminated in the inclusion of a contentious Directive Principle. I attempt to show that there is incredible diversity in the culinary habits of the people of this country and even among those belonging to the Hindu religion, many a times this diversity is influenced by a mix of socio-cultural factors. I examine the constitutional validity of this provision in light of Supreme Court judgements as well as its congruence to the principles of freedom of religion, of profession and above all the principle of secularism and its uniquely Indian interpretation. Through all this, I make a case of amending Article 48 so as to omit the cow protectionist clause, which has covertly given validity to mob lynching and cow vigilantism.
A Descriptive Study on Prescription Pattern of Intradialytic Complications in Patients Undergoing Hemodialysis
Authors: - Sai Lekshmi P , - Arun chandran R
Published: September 2024

Hemodialysis is a life-saving treatment for individuals with end-stage renal disease, but it is not without its challenges. This study examines the prescription pattern related to Intradialytic complications. It mainly aims to discern trends and improve management strategies for complications arising during Dialysis offering insights into optimizing prescription pattern within its clinical content. The goal of the study was to describe the Intradialytic complications associated with hemodialysis. Study also aimed to assess the prescribing pattern of drugs used for the treatment of intradialytic complications.
Assessing the Conservation Strategies and Ecological Impact of Mangrove Ecosystems in Mumbai, Maharashtra
Authors: - Rahul Mahamuni
Published: September 2024

Mangrove ecosystems are vital to coastal biodiversity, offering numerous ecological and socio-economic benefits, including shoreline stabilization, carbon sequestration, and habitat provision for diverse marine and terrestrial species. This study evaluates the conservation strategies employed for mangrove forests in Mumbai, Maharashtra, and assesses their ecological impact. Despite their importance, mangroves in Mumbai face threats from urban expansion, pollution, and climate change. Our research integrates field surveys, remote sensing data, and stakeholder interviews to analyze the effectiveness of current conservation measures, such as protected area designations, restoration projects, and community engagement initiatives. Findings indicate that while some strategies have successfully mitigated degradation and improved habitat quality, challenges persist, including inadequate enforcement and limited public awareness. The study highlights the need for enhanced conservation frameworks that incorporate adaptive management practices and robust community involvement. By understanding the ecological roles of mangroves and the effectiveness of conservation efforts, this research aims to provide actionable recommendations to safeguard these critical ecosystems for future generations.
Team Dynamics in Critical Care Unit a Nursing Context
Authors: - NANDEESH KUMAR P R
Published: September 2024

Critical care unit team dynamics are crucial for effective patient care, especially in nursing contexts. Key principles include skilled communication, effective decision-making, appropriate staffing, meaningful recognition, and authentic leadership. The COVID-19 pandemic has highlighted the need for adaptable team structures and cross-training. Effective team dynamics involve shared goals, mutual respect, and a collective approach to problem-solving. Critical care nurses play a vital role as patient advocates, educators, and communicators. Research shows that psychological safety, transactive memory, and leadership positively impact team performance in critical care settings. These concepts encourage innovation, learning, and the use of collective knowledge. Maintaining a positive team culture requires continuous effort, but embracing these principles can create a more rewarding work environment for nurses and colleagues.
Emotional Intelligence, Sense of Gratitude, and Compassion Fatigue of Medical-surgical Nurses in Government Hospitals in China
Authors: - Xiaohuan Cui , - Karen Cyril T. Cayanan , - Jeffrey V. Esteron
Published: September 2024

In China's healthcare system, compassion fatigue has emerged as a significant concern among medical surgical nurses, where they are facing the challenges of caring for an increasing number of patients with complex needs, which can significantly affect their emotional well-being and ability to provide high-quality care to patients. The study investigates the Relationship between emotional intelligence, sense of gratitude, and compassion fatigue among medical-surgical nurses in China. Medical surgical nurses with high emotional intelligence and a strong sense of gratitude may be more resilient and better equipped to cope with the emotional demands of their profession. This design will examine the degree of relationships between gratitude and compassion fatigue among medical surgical nurses in Hebei Province. Regression analysis was conducted to explore the Relationship between gratitude and compassion fatigue while considering potential confounding variables. Age, gender, and years of experience were controlled for as covariates in the analysis.The study's findings demonstrate the significant correlations between emotional intelligence, sense gratitude, and compassion fatigue among medical-surgical nurses. Additionally, the sociodemographic profile of the respondents did not show any significant difference in terms of emotional intelligence, gratitude, and compassion fatigue. The study also found that both emotional intelligence and sense of gratitude can predict compassion fatigue. The study highlights the importance of emotional intelligence and cultivating a sense of gratitude among medical-surgical nurses. By enhancing emotional intelligence and fostering gratitude, nurses may be better equipped to manage and prevent compassion fatigue. This can contribute to improved overall well-being and job satisfaction among nurses.
Feeling Safe: A Comprehensive Systematic Literature Review of Psychiatric Disorders through the Lens of Polyvagal Theory
Authors: Mansoor Iram
Published: September 2024

Safety on a psychological level is progressively renowned as fundamental to mental health issues andpsychological well-being. The concept of feeling safe based on polyvagal theory, proposed by Stephen Porges(2011), has emerged as a comprehensive structure for understanding the autonomic nervous system's role inregulating social behavior, emotional processing, and physiological reactions. This review aims to explore theapplication of polyvagal theory in the understanding of psychiatric disorders, with a focus on how autonomicnervous system dysregulation influences emotional and behavioral manifestations, thereby contributing to thedevelopment of effective therapeutic interventions aimed at enhancing feelings of safety and well-being in thepatients suffering from psychiatric disorders. The systematic literature review technique based on the PRISMAmodel was used for this purpose. Sources were obtained through PubMed, APA PsycArticles, PLOS, ResearchGate, Google Scholar, and PubMed Central (PMC) database, using different keywords as the primary descriptorand limiting the sources to English-language articles published in the last ten years from 2013 to 2023. Thereview synthesized findings from various studies investigating the association between the polyvagal theoryand psychiatric disorders, including anxiety disorders, depression, psychotic disorders, post-traumatic stressdisorder (PTSD), borderline personality disorder, and childhood disorders including conduct disorder, attentiondeficit hyperactivity disorder (ADHD), and autism spectrum disorder (ASD). The results exhibit that individualsuffering from these psychiatric disorders frequently displayed autonomic nervous system dysregulation, asproposed by the polyvagal theory, which seems to be a shared feature in many psychiatric disorders. Thesystematic review highlighted the significance of physiological aspects of mental health and indicates thatinterventions focusing on autonomic regulation may hold the potential to assuage the basic symptoms relevantto psychiatric disorders. Additional research work is defensible to clarify the primary mechanisms and improvethe implication of interventions which are based on polyvagal theory for better clinical outcomes.
Comparison of CD-138 Expression in Different Grades of Oral Squamous Cell Carcinoma
Authors: Basharat Shifa , Javaid Faryal , Sajjad Ayesha , Khattak Maria Tasneem , Ali Nosheen , Khan Maria
Published: September 2024

Objective: To compare the expression of CD-138 (Syndecan-1) in different morphological grades of oralsquamous cell carcinoma.Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Histopathology, Rehman MedicalInstitute Peshawar, Pakistan from June 2022 to February 2023.Methods: A total of 110 biopsy specimens from patients of either gender suspected as cases of oral squamouscell carcinoma (OSCC) underwent histopathological examination in the laboratory of Rehman MedicalInstitute. After eosin and hematoxylin staining, the diagnosis of oral squamous cell carcinoma and the gradewere confirmed. Thereafter, immunohistochemical analysis for CD-138 was performed. Age, gender, biopsysite intensity, and positivity for CD-138 expression in different grades of OSCC were the parameters recorded.Results: Mean age of the patients included in the study was 58.91 ± 6.42 years while the gender distributionshowed a male predominance with 98 (89.1%) males and 12 (10.9%) females. The most common affected sitein these patients was buccal mucosa of the oral cavity in 50 (45.5%) participants followed by 43 (39.1%)participants in which the affected site was tongue. The intensity of CD-138 (Syndecan-1) expression decreasedsignificantly with a change in the histological appearance of the tissue samples from well-differentiated topoorly differentiated morphology with a P-value of <0.01.Conclusion: Loss of CD-138 expression in oral squamous cell carcinoma is associated with a higher histologicalgrade, tumor aggressiveness and poor prognosis.
Evaluation of Electrolyte Levels in Patients with Acute Coronary Syndrome
Authors: Saleem Amna , Farooq Muhammad , Hadi Noor ul , Khan Jehandad
Published: September 2024

Objective: The study aims to assess electrolyte imbalances in patients diagnosed with acute coronarysyndrome (ACS) and to explore whether these imbalances are associated with poor clinical outcomes in ACS.Study Design: Cross-sectional analytical study.Place and Duration of Study: The study was conducted at the Department of Cardiology, Mardan MedicalComplex Mardan, Pakistan from September 2023 to December 2023.Methods: A cross-sectional study on 360 patients was conducted using the WHO sample size calculator.Patients from both genders were included in this study. Demographic information of patients was obtained.Serum electrolyte levels were done from the hospital's laboratory. Information was collected in predesignedproforma. Sampling was done via non-probability convenient sampling. Informed consent was taken from allpatients, ensuring confidentiality and the fact that there will be no risk to the patients who are taking part in this study.Results: Unstable angina was found in 60 (16.7%), in Non-ST-elevation myocardial infarction (NSTEMI) 154(42.8%) and in ST elevation myocardial infarction (STEMI) 146 (40.6%) patients. Hyponatremia was found to bein 108 (30%) patients, and it was associated in causing heart failure in around 58 (16.11%) patients.Hypokalemia was present in 65 (18%) patients and showed VT in 28 (7.77%) cases. Hypomagnesemia (31.9%)caused heart failure in 30 (8.33%) patients followed by VT in 26 (7.22%), cardiogenic shock in 24 (6.66%). Allelectrolyte disturbances of the current study carried statistical significance in causing complications i.e. P-value<0.001.Conclusion: We concluded that electrolyte disturbances are common in patients with acute coronarysyndrome, and they carry adverse outcomes with respect to ACS related complications and mortality.
Unraveling the Complexities of Coagulation Dysfunction in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Investigating the Interplay between Infection, Hypercapnia and Hemostatic Abnormalities
Authors: Ahmed Bilal , Imran Muhammad , Naeem Nimra , Haider Usman , Rauf Muhammad Atif , Iqbal Qaiser
Published: September 2024

Objective: To understand how the acute exacerbations of chronic obstructive pulmonary disease (COPD) canlead to coagulation dysfunctions causing hemostatic abnormalities (prolonged prothrombin time, slightlylonger activated partial thromboplastin time, higher fibrinogen levels, higher D-dimer levels, and slightly lowerplatelet counts).Study Design: Comparative cross-sectional.Place and Duration of Study: The study was conducted at the Department of Internal Medicine Pak EmiratesMilitary Hospital (PEMH) Rawalpindi, Pakistan during the period of July 2023 to December 2023.Methods: The current study utilized patients with a confirmed diagnosis of Acute Exacerbation of ChronicObstructive Pulmonary Disease (AECOPD) who were hospitalized in the respiratory care unit and were above 50years of age. A total of 200 patients were accessed including their demographic characteristics (age, gender,residence, and job), clinical parameters (spirometry results (Forced expiratory volume in one second/Functional vital capacity ratio), complete blood counts, fibrinogen, prothrombin, activated partial thromboplastin time, D-dimers and arterial blood gas analysis. The intricate relationship between coagulation dysfunction and acute exacerbations of chronic obstructive pulmonary disease was analyzed using SPSS 26.Results: The results obtained that; patients with acute exacerbation of chronic obstructive pulmonary diseasehad prolonged prothrombin time (13.5 ± 1.2 seconds, P < 0.001) slightly longer aPTT (32.1 ± 2.5 seconds, P =0.014), along with higher fibrinogen levels (350.2 ± 45.8 mg/dL, P < 0.001) and D-dimer levels (550.4 ± 120.3ng/mL, P = 0.002), as compared to patients with stable chronic obstructive pulmonary disease. The plateletcounts of Acute exacerbation of chronic obstructive pulmonary disease patients obtained were slightly lower(260.3 ± 45.4x10^3/μL, P = 0.009) compared to stable chronic obstructive pulmonary disease patients.Furthermore, results provided that coagulation dysfunction was significantly associated with infection,hypercapnia, and acute exacerbation of chronic obstructive pulmonary disease. The prevalence of coagulationdysfunction markers was higher among patients with acute exacerbation of chronic obstructive pulmonarydisease.Conclusion: Coagulation dysfunction and its associated risk factors are higher in patients with acuteexacerbation of chronic obstructive pulmonary disease and are elevated with increased exposure to airpollution.
Implementasi Pemasaran Digital Pada Breadlife Melalui Media Video
Authors: Ramadani Arienda Gitty , Marheni Dewi Khornida , Kusweanto Fanesha Nissy
Published: September 2024

Digital Marketing is the main key for business in these days to be able to thrive. Breadlife Batam is a store specialized in selling and making bread and pastry in an Japanese Artisan Bakery style under PT Kunci Mas Batam. All this time, there are some Batam residents which do not recognize Breadlife as a good national franchise, have not tried the products and also feel sceptic towards the brand quality, considering the price is expensive enough if compared to other local bread brands.Purpose - This PkM activity is expected to be able to help Breadlife store to promote its product to the society with video media.Research Method - The data collection method used is observation and interview. Findings - As a result, there are many good responds from the society, hence Breadlife brand will be increasingly known by the Batam societies. Implication - The contribution of the research findings for Breadlifeâ€™s owner are many good responds from the society, hence Breadlife brand will be increasingly known by the Batam societies. The contribution of the research findings for the next researcher are can be used as a reference source for further research to support research related to digital marketing.
Opening the gate: A resource to support Victorian schools to activate school grounds and open spaces for community use
Authors:   VicHealth
Published: September 2024

This resource provides practical tips to support school leaders to activate their open spaces after hours and on weekends, unleashing the many benefits for schools and communities.
Advances in understanding and managing celiac disease: Pathophysiology and treatment strategies
Authors: Ge Hao-Jie , Chen Xu-Lin
Published: September 2024

In this editorial, we comment on an article published in the recent issue of the World Journal of Gastroenterology . Celiac disease (CeD) is a disease occurring in genetically susceptible individuals, which is mainly characterized by gluten intolerance in the small intestine and clinical symptoms such as abdominal pain, diarrhea, and malnutrition. Therefore, patients often need a lifelong gluten-free diet, which greatly affects the quality of life and expenses of patients. The gold standard for diagnosis is intestinal mucosal biopsy, combined with serological and genetic tests. At present, the lack of safe, effective, and satisfactory drugs for CeD is mainly due to the complexity of its pathogenesis, and it is difficult to find a perfect target to solve the multi-level needs of patients. In this editorial, we mainly review the pathological mechanism of CeD and describe the current experimental and improved drugs for various pathological aspects.
Delayed diagnosis in inflammatory bowel disease: Time to consider solutions
Authors: Lv Hao , Li Hao-Yu , Zhang Hao-Nan , Liu Yang
Published: September 2024

In this editorial, we discuss a recently published manuscript by Blüthner et al in the World Journal of Gastroenterology , with a specific focus on the delayed diagnosis of inflammatory bowel disease (IBD). IBD, which includes Crohn's disease and ulcerative colitis, is a chronic intestinal disorder. A time lag may exist between the onset of inflammation and the appearance of signs and symptoms, potentially leading to an incorrect or delayed diagnosis, a situation referred to as the delayed diagnosis of IBD. Early diagnosis is crucial for effective patient treatment and prognosis, yet delayed diagnosis remains common. The reasons for delayed diagnosis of IBD are numerous and not yet fully understood. One key factor is the nonspecific nature of IBD symptoms, which can easily be mistaken for other conditions. Additionally, the lack of specific diagnostic methods for IBD contributes to these delays. Delayed diagnosis of IBD can result in numerous adverse consequences, including increased intestinal damage, fibrosis, a higher risk of colorectal cancer, and a decrease in the quality of life of the patient. Therefore, it is essential to diagnose IBD promptly by raising physician awareness, enhancing patient education, and developing new diagnostic methods.
Sustainable Entrepreneurship in Agribusiness: A Case Study in A Brazilian Agro-Industrial Cooperative
Authors: Johann Daiane , Nora Gabriela Almeida Marcon , Angelucci Camila , Guimarães Lilian da Silveira
Published: September 2024

Purpose: To identify sustainable practices in an agro-industrial cooperative in Rio Grande do Sul - RS (a southern state of Brazil well known for its significant participation in the national production of agribusiness), correlating them to the Sustainable Development Goals (SDGs) of the 2030 Agenda, as well as analyzing how sustainable entrepreneurship is transforming the lives of families and the space where they live.
Methodology/approach: The study used primary data collection through a semi-structured interview that took place in July 2020 with the Environmental Coordinator, also made use of secondary data with observation, document analysis through consultation on the cooperative's website, documents, and internal controls to generate evidence convergence and strengthen construct validity through source triangulation, in which case study findings are supported by more than one source of evidence.
Originality/Relevance: Sustainable entrepreneurship refers to the discovery, creation and exploitation of business opportunities that contribute to sustainability, generating socio-environmental gains for society.
Key findings: The studied Cooperative assumes a socio-environmental responsibility role through the developed activities that generate value to the cooperative members in an innovative, safe, and sustainable way, in addition to benefiting the surrounding community with sustainable practices, therefore the Cooperative in question is certified with the Certificate of Environmental Distinction, proving its commitment to sustainable development and good environmental practices. Educational and environmental practices that contribute to the promotion of sustainability in agribusiness were identified, such as the use of clean technologies in production and the proper management of waste generated by agro-industrial activity. These practices generate socio-environmental gains for society.
Theoretical/methodological contributions: This study brings a relevant theoretical contribution linked to sustainability and entrepreneurship in agribusiness based on findings in the practices of a cooperative. In addition to also contributing at an environmental level, this work contributes to contributing to the financial and social pillars that sustainability encompasses.
Komunikasi Mitigasi Bencana di Kota Industri Cilegon
Authors:   LSPR Institute of Communication & Business, Yunia Anita , Yulianti Wulan ,   LSPR Institute of Communication & Business, Harwinda Alfilonia ,   LSPR Institute of Communication & Business, Pinariya Janette Maria ,   LSPR Institute of Communication & Business
Published: September 2024

Indonesia's geographical and geological factors, which are located on the Pacific Ring of Fire, are one of the factors causing earthquakes, volcanic eruptions, tsunamis, floods, landslides, and extreme weather. One area that is of concern to the government in its disaster management efforts is Cilegon City, Banten Province because it has a fairly high level of disaster vulnerability. This city has the potential for a large earthquake accompanied by a tsunami with waves as high as 8.28 meters which holds the potential for danger in the form of technological failures that cause damage to infrastructure, disease, the environment, and even death to humans. This research aims to analyze program steps and mitigation communication strategies in the city of Cilegon. This research was conducted in January – September 2022 in Cilegon City, Banten Province. The method used in this research is descriptive qualitative. The results show that efforts focused on dealing with disasters in Cilegon City were carried out through outreach and education. As a follow-up to this activity, the community will be empowered with training and assistance which will later be further developed with capacity-building activities to improve community skills in disaster response.