bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Perencanaan dan Pencatatan Keuangan Pada Usaha Mikro Kecil dan Menengah Di Tlogosari Wetan
Authors: Mardhiyaturrositaningsih
Published: May 2023

Perencanaan dan Pencatatan keuangan membantu Pelaku Usaha Mikro Kecil dan Menengah (UMKM) dalam pengelolaan usaha dan sebagai prasyarat dalam mengakses pembiayaan perbankan. Usaha Mikro Kecil dan Menengah di Tlogosari Wetan dalam implementasinya relative terbatas dalam melakukan perencanaan dan pencatatan keuangan yaitu sejumlah 27 persen. Pelatihan literasi perencanaan dan pencatatan keuangan UMKM di Tlogosari Wetan diperlukan dengan tujuan untuk meningkatkan literasi Usaha Mikro Kecil dan Menengah mengenai perlunya perencanaan dan mekanisme pencatatan keuangan. Kegiatan pengabdian pelatihan literasi keuangan ini menggunakan metode Service Learning (SL) pada 51 UMKM. Hasil dari kegiatan ini menunjukan adanya peningkatan pengetahuan pelaku UMKM mengenai perencanaan dan pancatatan keuangan sebelum dan setelah pelatihan.
Pelatihan Diversifikasi Produk Batik Ecoprint Guna Meningkatkan Daya Jual dan Daya Tarik Produk
Authors: Zia'ul Huda Zamira , Wulandari Dewi , Pungky Rahmawati Inka , Wahyuni Indah , Yulianti Rika , Tri Rahmawati Ayu , Dewi Atika Sari Fatma , Pangestuti Indriyani , Sari Latifah , Adhie Perdana Bintang
Published: May 2023

ABSTRAK

 

Program diversifikasi produk ecoprint ini merupakan salah satu bentuk kegiatan pengabdian masyarakat dalam hal pengembangan penggunaan teknik ecoprint dalam rangka memperluas daya jual dan menambah daya tarik produk ecoprint. Metode pelatihan dilakukan bersama dengan pihak pengelola produk ecoprint dengan 4 tahapan, yaitu 1) tahap penyampaian materi ; 2) tahap demonstrasi ; 3) tahap hands-on interaktif ; dan 4) tahap evaluasi. Hasil dari kegiatan pengabdian masyarakat ini yaitu 1) terciptanya diversifikasi produk batik ecoprint berupa kaos, jilbab dan totebag ; 2) Kegiatan pelatihan pembuatan ecoprint diikuti oleh 13 orang peserta termasuk di dalamnya kelompok KKN MBKM 5 UNS dan warga setempat ; 3) peserta pelatihan antusias dan memberikan respon yang positif terhadap pelatihan pembuatan ecoprint  ; dan 4) produk ecoprint dengan hasil terbaik akan dipamerkan di kegiatan expo KKN UNS.

 

Kata kunci : ecoprint ; diversifikasi produk ; pelatihan 

ABSTRACT

 

The ecoprint product diversification program is a form of community service activity in terms of developing the use of ecoprint techniques in order to expand selling power and increase the attractiveness of ecoprint products. The training method is carried out together with the ecoprint product manager in 4 stages, namely 1) the stage of delivering the material; 2) demonstration stage; 3) interactive hands-on stage; and 4) evaluation stage. The results of this community service activity are 1) the creation of a diversified ecoprint batik product in the form of t-shirts, headscarves and totebags; 2) The ecoprint making training activity was attended by 13 participants including the UNS MBKM 5 KKN group and local residents; 3) the training participants were enthusiastic and gave a positive response to the training on making ecoprints; and 4) ecoprint products with the best results will be exhibited at the Exhibition of UNS KKN.

 

Keywords: ecoprint; product diversification; training
TRADUCTION ET VALIDATION EN FRANCAIS D'UNE QUESTION UNIQUE COMME OUTIL DE DEPISTAGE DES CONSOMMATIONS A RISQUE D'ALCOOL EN SOINS PRIMAIRES
Authors: BESNIER M , LE GOFF D
Published: May 2023

Les consommations à risque d’alcool étaient, en France, la deuxième cause de mortalité évitable en 2017. Des tests comme AUDIT (Alcohol Use DIsorders Test) ou FACE (Fast Alcohol Consumption Evaluation) sont utilisables en soins primaires pour repérer les consommations d’alcool à risque. Ils sont peu utilisés par les médecins généralistes (MG), jugés peu adaptés à la pratique en soins primaires1. En 2009, une étude américaine a validé une question unique (QU) permettant le repérage des consommations d’alcool à risque en soins primaires2 : “How many times in the past year have you had X or more drinks in a day?”, où X était 5 pour les hommes et 4 pour les femmes.
PROFILS DES PATIENTS AYANT UN TRAITEMENT PAR INHIBITEUR DE LA POMPE A PROTONS SUR LE LONG COURS
Authors: VERNA V , RENOUX C
Published: May 2023

Introduction. En France, 15 % des inhibiteurs de la pompe à protons (IPP) seraient prescrits hors des indications d’autorisation de mise sur le marché. Les représentations des patients sur leur IPP pourraient être un frein à leur arrêt. Objectif. Explorer les représentations des patients sur l’IPP qui leur était prescrit depuis plus d’un an et son éventuel arrêt. Méthode. Étude qualitative inspirée de l’analyse interprétative phénoménologique auprès de 14 patients majeurs prenant un IPP depuis plus d’un an. Résultats. Les patients avaient une représentation positive de l’IPP. Trois profils de patients prenant un IPP au long cours ont émergé de l’analyse : un premier profil où les patients considéraient l’IPP comme un médicament obligatoire, avec une prise continue et un arrêt inenvisageable ; un deuxième profil où les patients géraient la prise de leur IPP afin de soulager leurs symptômes ; un troisième profil où les patients respectaient une « prescription médicale » avec une prise continue et un arrêt possible après discussion avec leur médecin. Conclusion. La prise en compte des représentations des patients concernant leur IPP pourrait être utile au cours de la réévaluation de leur ordonnance. Le repérage d’un des trois profils par le médecin serait une étape clé pour amorcer une démarche de déprescription.
PEMIKIRAN HADIS Dr. SULIDAR M.Ag.
Authors: Winda Sari
Published: May 2023

ABSTRACT                                                                

Sulidar is one of the scholars of Hadith in North Sumatra. His thoughts in the field of hadith are about the meaning of hadith and sunnah. Some scholars distinguish between the meaning of Hadith and Sunnah such as T.M. Hasbi ash-Shiddieqy, Sulidar made absolutely no difference in defining Hadith and Sunnah. He unites them in one sense, namely words, deeds, and taqrir which were leaned on the Prophet Muhammad. In this case, what he meant by Hadith and Sunnah after Muhammad was appointed as a prophet and apostle, namely after the age of 40 (forty) years. Literature review research methods. The purpose of this research is to find out the thoughts of Sulidar Hadith.

 

 

 

ABSTRAK

Sulidar salah saorang pengkaji Ilmu Hadis di Sumatera Utara. Pemikirannya dalam bidang hadis adalah mengenai pengertian hadis dan sunnah. Sebagian ulama membedakan pengertian Hadis dan Sunnah seperti T.M. Hasbi ash-Shiddieqy, Sulidar sama sekali tidak membuat perbedaan dalam mendefenisikan Hadis dan Sunnah. Ia menyatukannya dalam satu pengertian, yaitu perkataan, perbuatan, dan taqrir yang disandarkan kepada Rasulullah saw. Dalam hal ini, yang dimaksudkannya dengan Hadis dan Sunnah setelah Muhammad diangkat sebagai nabi dan rasul, yaitu setelah berumur 40 (empat puluh) tahun. Metode penelitian kajian pustaka. Tujuan penelitian ini untuk mengetahui pemikiran Hadis Sulidar.
METODOLOGI PENELITIAN SANAD DAN MATAN HADIS
Authors: Yuzaidi
Published: May 2023

ABSTRACT                                                                

Hadith is the second source of law for Muslims after the Koran. Because many Hadiths have been narrated by narrators with different degrees, it is necessary to conduct research on Hadith in terms of sanad and Matan so that these traditions can be applied in everyday life. This research method is literature review. The sanad research method is guided by the hadith sohih criteria and observational research consists of avoiding syaz and illat, not contradicting the Koran. This study aims to describe the methodology in the research of hadith sanad and observations so that it is easy for hadith researchers to determine the quality of a hadith.

 

 

 

ABSTRAK

Hadis sumber hukum kedua umat islam setelah Alquran. Karena banyak Hadis yang telah diriwayatkan oleh para perawi dengan derajat yang berbeda-beda maka perlu diadakan penelitian Hadis dari segi sanad dan Matan agar hadis tesebut dapat diaplokasikan dalam kehidupan sehari-hari. Metode penelitian ini adalah kajian pustaka. Metode penelitian sanad berpedoman pada kriteria hadis sohih dan penelitian matan terdiri dari terhindar dari syaz dan illat, tidak bertentangan dengan Alquran. Penelitian ini bertujuan untuk mendeskripsikan metodologi dalam penelitian sanad dan matan hadis agar peneliti hadis mudah untuk menentukan kualitas suatu hadis.
Penerapan Model Kooperatif Learning Tipe Think-Pair-Share Pada Pokok Bahasan Sistem Peredaran Darah
Authors: Huda Hisbulloh
Published: May 2023

Pemantapan suatu metode yang tepat dalam kegiatan pembelajaran menempati peranan yang cukup penting. Keberhasilan proses pendidikan sangat tergantung pada tingkat pemahaman siswa yang berimplikasi pada hasil belajar siswa pasca Kegiatan Belajar Mengajar (KBM). Dalam pelajaran IPA prestasi belajar siswa selain ditentukan oleh tingkat pemahaman dan penguasaan materi, juga ditentukan oleh metode yang digunakan dalam pembelajaran dan perolehan pengetahuan terkait untuk memecahkan permasalahan dalam kehidupan sehari-hari.Metode yang digunakan dalam peningkatan pemahaman materi peredaran darah pada manusia pada pelajaran IPA siswa kelas VIII-E adalah Menggunakan Model Cooperatif Learning Tipe Think - Pair - Share. Melalui Model Kooperatif Learning Tipe Think-Pair- Share siswa lebih memahami dan menghayati pelajaran IPA dan MTs Negeri 4 Jombang seperti kenyataan yang ada dalam kehidupan sehari-hari, sehingga akan membawa pengaruh positif pada prestasi belajar siswa, dibandingkan hanya menggunakan metode ceramah yang membuat siswa hanya mampu membayangkan tanpa mendapatkan pengalaman belajar yang konkrit. Dari hasil penelitian dapat disimpulkan bahwa melalui penggunaan Model Cooperatif Learning Tipe Think-Pair- Share mampu meningkatkan pemahaman materi sistem peredaran darah  pada pelajaran IPA siswa kelas VIII-E Negeri 4 Jombang.
Kepastian Hukum Pelaksanaan Lelang Online Melalui Media Internet
Authors: Gunawann Cynthia , Maryono Maryono , Sudirman Maman
Published: May 2023

Pembahasan mengenai kepastian hukum pelaksanaan lelang  online melalui media internet. Jenis penelitian yang dipakai dalam penelitian ini adalah metode yuridis normatif. Pendekatan penelitian yang digunakan adalah, Pendekatan Perundang-undangan (Statute Approach), dan Pendekatan Kasus (Case Approach). kepastian hukum  pelaksanaan lelang online  melalui media  internet (online auction) oleh KPKNL merupakan transaksi  yang sah, dikuatkan dengan Undang-Undang Republik Indonesia Nomor 11 tahun 2008 tentang informasi dan transaksi elektronik dan dilakukan perubahan pada Undang-undang informasi dan transaksi elektronik Republik Indonesia Nomor 19 tahun 2016 yang  telah disahkan oleh pemerintah, serta adanya  perlindungan hukum  bagi pelaku atau pelaksana lelang sesuai dengan KUHPerdata. Implementasi pelaksanaan lelang online  melalui media  internet pada saat ini telah membantu masyarakat pelaku  lelang, sehingga dapat membantu mengurangi beberapa permasalahan  dalam   transaksi melalui media internet (online auction).
Sharing the World: Using Study Abroad to Enhance an On-Campus Service-Learning Project
Authors: DAVIS CAITLYN , TIETZ JULIE
Published: May 2023

The purpose of this paper is to illustrate use of a study abroad opportunity to support a service-learning experience. The study abroad component was a semester-long, multiple-country program in Central America and the service-learning project was an afterschool program for rural elementary and middle school students. Combining the two resulted in the opportunity to use the study abroad experience as a platform to share with the students the culture and issues facing others in the global community.
When Gender Is a Problem in Islamic Theology and Qur’anic Tafsir
Authors: Barlas Asma
Published: May 2023

This paper critiques the tendency to map sex/gender onto God and to interpolate sex/gender partisanship into God's speech in Islamic theology and tafsir (classical and feminist), which generates patriarchal readings of the Qur'an. The first practice violates the theologeme of God's incomparability, while the second imputes a gender hierarchy to the Qur'an even though there is no concept of gender itself in the text. Instead, the paper proposes an anti-patriarchal reading that is more congruent with God's self-disclosure as well as with key Qur'anic teachings that affirm the ontic equality of women and men.
Spotlight on Victoria, Australia
Authors: Leponiemi Lasse
Published: May 2023

This research was conducted by HundrED to examine perceived needs of all stakeholders in education globally, through a State of the Debate review and Global Youth Survey. As young people are too often excluded from educational change, a core part of this exploration gains key insights from youth internationally. Everyone has a role to play in improving education, from students to systems leaders, to academics and teachers. It is time to engage all stakeholders, everywhere, to understand that we can utilize deep insights and change from around the world in our continuously interconnecting global community. This will allow us to move forward together, innovating for an education that allows every child to flourish, no matter what happens in life.
La autonomía y el compromiso social de la universidad: un recorrido histórico
Authors: Brambilla Pautasso Carla , Méndez Barbara
Published: May 2023

La tesis central de este artículo se puede sintetizar en el hecho de que el compromiso social de la universidad anida en el concepto de autonomía. Aquí se exploran algunas notas significativas que -a lo largo de la historia y desde sus orígenes- ponen en evidencia la noción de autonomía como rasgo inherente de la universidad. Se subrayan algunas relaciones con los poderes político - económico, pero también con la sociedad civil; para ello se han seleccionado algunos autores clásicos que han discurrido sobre la universidad y la autonomía contribuyendo a pensar qué es la cosa universitaria. El sino de la institución universitaria y de sus actores es el compromiso social que inspira la gestión del conocimiento: la producción de nuevas ideas, la creación de nuevos modos de comprensión e interpretación del mundo natural y social y la formación de intelectuales y profesionales. Se esbozan, también, líneas que permiten poner en tensión las tres misiones sustantivas de la universidad: docencia, investigación y, particularmente, la extensión; a modo de ejemplo, se desarrollan algunas consideraciones sobre esas articulaciones.
Prenatal Education In the Qur'an
Authors: Fitriyah Lailatul Fitri
Published: May 2023

Prenatal education is very important education in child development, because prenatal education is foundation education for childrens. In the Al-Qur’an there is verse wich explain about prenatal education on of them is surah An-nahl verse 78 . In this research the writer reaserched surah an-nahl verse 78 according of the commentators of Al-Qur’an. In this research  uses library reaserch and  this reaserch method uses the Maudhu’I method. The purpose of this research is to knowing of explain the commentators of Al-Qur’an about prenatal education in the Qur’an Surah An-Nahl verse 78.  The purpose of this research to know opinion of commentator of the Qur’an about prenatal education in the surah an-nahl verse 78. In this research the are some opinions commentator of the Qur’an, that is the first, the are commentator   who think is prenatal education can occur at the stage of pregnance because senses are working and can receive stimulation from outside the womb,  the second opinion,  the are commentator   who think is prenatal education can not happen because the senses can not working and can not receive stimulation from outside the womb, third opinion, does not link surah an-nahl verse 78 with prenatal education.
DIMENSI EMOSI PADA SURAT AL BAQARAH AYAT 155 DALAM TAFSIR FI ZHILAL AL QURAN KARYA SAYYID QUTB
Authors: Halimah Ulfatul
Published: May 2023

Setiap manusia mempunyai emosi dalam dirinya terlebih ketika ia mengalami ujian dan cobaan. Tidak sedikit ditemukan kasus bunuh diri karena tidak bisa menahan emosi saat mengalami ujian dari Allah. Oleh karena perlu adanya solusi dan pencerahan dalam menghadapi permasalan seperti ini. Artikel ini akan membahas mengenai dimensi emosi dalam surat al Baqarah ayat 155 dalam pandangan Sayyid Qutb. Artikel ini menggunakan metode library research dengan data primer Tafsir Fi Zhilalil Quran dengan teknik pengumpulan data dokumentasi. Dalam penelitian ini ditemukan bahwa salah satu cara menghadapi ujian adalah dengan mengelola emosi sabar dan pasrah kepada Allah.
Assessment of Seagrass and Macrobenthic Algae in Pujada Bay, Mati, Davao Oriental
Authors: AngSinco-Jimene Lea , Nogodula Reynaldo , Tans Diego
Published: May 2023

The Status of the existing seagrass and algae meadows of Pujada Bay, Mati, Davao Oriental was assessed from September 2001 to August 2002. The structure of seagrass and algae communities was determined using the Transect-Quadrat Method. A total of g species of seagrass was identified in the study area: These were Cymodocea rotundata, Cymodocee senulata, Enhatus acoroides, Haludule pinifolia, Haludole unineniis, Halophila minor, Halophila ovalis, Syringodium isoetifolium and Thalassia hemprichii. Taitaidaga station had the highest percent cover (41%) of seagrass dominantly covered with species of H. ovalis (11%) and H. minor (8%) while Manguihay station had the lowest percent cover (24%) of T. hernprichii (12%) and C. rotundata (5%). In terms of its density (shoots/m2), it is noted that Lawigan had the highest density (1,720 shoots/m2) of S. isoetifolium (438 shoots/m2) and T. hemprichii (431 shoot/m2) while Manguihay (955 shoots/m2) had again the lowest density of seagrass species where T. hemprichii (524 shoot/m2) and H. ovalis (169 shoot/m2) dominated the site. Fifty-seven species of algae were identified. These consist of Chlorophyta (green algae) having 25 species under 9 families: Rhodophyta (Red algae) with 16 species under 6 families and Phaeophyta (Brown algae) with 13 species under 4 families. The highest percent frequency (41 %) of macrobenthic algae is noted in Taitaidaga station while Manguihay (69%) the lowest. Lawigan had the highest percent cover (11%) and Manguihay (5%) had the least cover. It is dominantly covered with green algae (43%) followed by red algae (35%) and brown algae (27%).
Assessing Innovative Activity and Commercialization in SMEs – A Study of SMEs in Punjab
Authors: Rehman Munib ur , Rehman Syed Khalil ur , Khan Romaisa
Published: May 2023

Small and medium Enterprises are vital in the economy of any country. They generate employment, business besides supporting big industries. Improvement in the services and products of SMEs ensures their survival and transformation to the bigger institutions, In Pakistan Majority of enterprises are SMEs and are pivotal in strengthening the national economy. How they are improving their working at par with market needs is the subject touched upon very little in Pakistani environment. This study aims at mapping the innovation practices in the SMEs irrespective their sector in terms of commercialization so as to ascertain their strategies for better service and production delivery which is significant in their survival. For the purpose. 250 SMEs, selected through purposive random sampling with the help of SMEDA, Provincial Industries Departments, SECP and Lahore Chamber of Commerce and Industry, around the country were studied. Data was collected through an online questionnaire, based on the work Tim Mazzarol et al (2011), comprising 40 items. 12 respondents were interviewed through semi-structured interviews. This study is of articulation in nature and data was analyzed SPSS and Envivo. The results indicated the patterns and preferences of SMEs towards innovation and commercialization by giving a bleak picture in SMEs. The findings suggest massive change of policies in SMEs to make them real booster of economy.
PERAN SATUAN LALU LINTAS DALAM MENGURANGI PELANGGARAN LALU LINTAS DI TULUNGAGUNG
Authors: Kuncoro Wisnu Setiyawan
Published: May 2023

The purpose of this study was to determine the role of the Traffic Unit in Reducing Violations in Tulungagung. This is due to the decreasing trend of traffic violations in Tulungagung. In an effort to reduce the number of traffic violations, the Tulungagung Police Satlantas prioritizes preventive and follow-up or repressive actions. This research method is descriptive qualitative. Data collection techniques with in-depth interviews and observation. The results showed that in reducing violations in Tulungagung is an ideal role, expected role and actual role. The Traffic Unit in Tulungagung takes preventive measures by socializing, warning students and repressive in the form of ticketing and confiscation in reducing the number of traffic violations. Thus there is a need for public understanding and awareness to avoid traffic violations. This is where the role of the police is needed to regulate and direct the public to accept and implement the strategies or methods used by the police in dealing with traffic violations.
RUISLAG TANAH WAKAF PERSPEKTIF IMAM AS-SYAFI’I: Kasus di Mushola Abdurrahman Al Jamil Bumen Bumirejo Kab. Wonosobo
Authors: Luhfiana Mia , Bashori Akmal
Published: May 2023

Waqf is a form of Islamic socio-religious worship which is highly recommended for Muslims, because waqf will always distribute rewards to those who donate it even though the person concerned has died. While swapping waqf is replacing the waqf property with other assets because there is benefit or indeed it must be replaced which in Islam is known as istibdal. The problems examined in this study are first, how is the practice of implementing swaps for waqf land at the Andurrahman al Jamil prayer room in Bumen Hamlet, Bumirejo Village, Mojotengah District, Wonosobo Regency. Second, how is the law of the swap practice from the perspective of Imam As-Shafi'i. to find out whether the practice of swapping is in accordance with the As-Shafi'i Madzhab or not. This research uses field research methods with data analysis and processing on objects that compare the law of Imam As-Syafi'i with the practice of swapping rolls that occur in the Bumen, Bumirejo, Mojotengah, Wonosobo neighborhoods. The results of the first study show that in the practice of exchanging waqf land that took place at the Abdurrahman Al Jamil Mosque, Bumen Hamlet, Bumirejo, Mojotengah, Wonosobo, it was a practice of exchanging waqf land at the Al Jamil Mosque and the land of one of the residents as an extension of the Abdurrahman Mosque. The reason for this exchange is to maintain the continuity of the benefits and objectives of the Al Jamil mosque waqf because the mosque is not well managed. Second, when viewed from the perspective of Imam Syafi'i this practice is not in accordance with Islamic law stipulated by Imam Syafi'i. In his opinion, the practice of back-and-forth is not allowed. The stated permissibility of swapping is not a law, but only as an alternative so that the sustainability of the benefits is not lost (more maslahah).
Application of Indonesian National Standard (SNI) on Helmets of Two-Wheeled Motor Vehicle Riders: Consumer Rights and Obligations of Business Actors
Authors: Lumban Gaol Christopher Panal
Published: May 2023

This paper discusses the application of the Indonesian National Standard (SNI) on two-wheeled motorized vehicle helmets and its implications for consumer rights and obligations of business actors. Based on the Regulation of the Minister of Industry of the Republic of Indonesia Number: 79/M-IND/PER/9/2015, SNI for helmets of two-wheeled motorized vehicle riders is compulsorily enforced. Business actors who produce and/or import helmets must meet SNI requirements and have a product certificate using the SNI mark installed on the product. Consumers have rights protected by the Consumer Protection Law, including the right to comfort, security, and safety in consuming goods and/or services. They have the right to true, clear and honest information about helmet products, and have the right to raise opinions and complaints. If the helmet product does not comply with the agreement, the consumer is entitled to compensation and compensation. On the other hand, business actors have an obligation to provide true, clear, and honest information about the condition and guarantee of helmet products. They must treat consumers properly and honestly, as well as provide compensation, indemnity and replacement if the helmet product does not comply with the agreement. The Indonesian National Standard (SNI) for helmets of two-wheeled motorized vehicle riders, such as Helm SNI 1911:2007, specifies technical requirements related to materials, designs, and features that must be met by helmets. These requirements include materials that are strong, do not change by temperature changes, and do not cause irritation to the skin. The helmet design must also meet certain criteria, including height, ventilation, and bearing. Full face helmets and open face helmets have different technical requirements, such as ear protection, neck covers, shields, or chin caps for full face helmets, and hoods, protective linings, straps and more for open face helmets.In conclusion, this paper underlines the importance of applying SNI to two-wheeled motorized vehicle helmets to maintain product quality, safety, and comfort. Consumers have rights that must be protected, while business actors have the obligation to meet SNI requirements and provide good service to consumers. With SNI, it is hoped that two-wheeled motorized vehicle helmets on the market can meet the standards that have been set, so as to provide better protection for riders.
VACCINATION EFFECTIVENESS IN THE POPULATION OF THE ELDERLY PEOPLE AND THE AGING OF THE IMMUNE SYSTEM
Authors: ZUZIAK Patrycja , PRZEORSKI Krzysztof , DEREZIŃSKI Marcin , MENDOWSKI Mateusz , KLINIEC Katarzyna
Published: May 2023

The progress of civilization so far has not solved the main cause of various health problems af-fecting seniors, which is the aging process. Among the possible causes of this phenomenon im-munosenescence is mentioned, which is the progressive accumulation of functional pathology and the increasing loss of features typical of a healthy immune system. This review, although unable to exhaust the subject, focuses mainly on describing the aging of the most important cells of the immune system (T and B lymphocytes), with particular attention to the relationship be-tween the dysfunction that accumulates in them over time and the effectiveness of vaccinations in this population. The authors hope that the studies presented will be helpful in gaining a deeper understanding of the implications of aging of the immune system for vaccination strategies.
Penguatan Bahasa Indonesia sebagai Identitas Nasional Melalui Poster Interaktif pada Instagram @Bastra.Id
Authors: Nurrahmah Faiza
Published: May 2023

Artikel ini menjelaskan nasib bahasa Indonesia sebagai identitas nasional di era teknologi informasi dan komunikasi. Perkembangan pesat teknologi informasi dan komunikasi telah mengakibatkan beberapa kesalahan dalam penggunaan bahasa Indonesia oleh masyarakat, baik lisan maupun tulisan. Artikel ini dibuat berdasarkan metode penelitian deskriptif kualitatif dengan objek studi akun Instagram @BASTRA.ID yang merupakan salah satu aktivis bahasa di media sosial. Berdasarkan pengamatan, keberadaan akun ini telah menjadi media pembelajaran bahasa Indonesia di media sosial yang terus mengingatkan pentingnya menggunakan bahasa Indonesia sesuai dengan kaidahnya. Akun ini secara tidak langsung mengubah kebiasaan masyarakat Indonesia dalam berbicara Bahasa Indonesia melalui poster-poster interaktif yang diunggah. Perubahan dalam kebiasaan disiplin berbahasa diamati di kolom komentar setiap postingan.
Arabiske Medier
Authors: Galal Ehab
Published: May 2023

I slutningen af 1970’erne, da jeg bosatte mig i Danmark, var det ikke muligt gennem de danske eller andre medier dagligt at følge med i de arabiske landes udvikling. De eneste muligheder var et meget dårligt radiosignal, videoer eller kassettebånd af dårlig kvalitet, der kunne lejes fra en arabisk forretning på Israels Plads i centrum af København, eller at købe en tre dage gammel egyptisk avis: al-Ahram. For at købe avisen var jeg nødt til at tage hele vejen til Københavns Hovedbanegård og betale et relativt højt beløb for den. Med min økonomiske formåen var det begrænset, hvor mange gange om måneden jeg havde råd til det.
Muslimske Kvinners Forhold til Islamske Kilder og Autoritet i Trondheim
Authors: Eriksen Eli-Anne Vongraven
Published: May 2023

Denne artikkelen ser nærmere på hvordan muslimske kvinner i Trondheim forholder seg til ulike former for islamske kilder og autoritet i sine søk etter kunnskap om islam. Artikkelen tar utgangspunkt i en studiegruppe for muslimske kvinner i Trondheim, og undersøker hvilke kilder og autoriteter kvinnene velger å søke kunnskap fra, hvordan de anvender disse kildene og autoritetene, og hvorfor. Artikkelen tar også for seg formålet og aktivitetene til studiegruppa, samt fremveksten og utviklingen av den. På denne måten tilbyr artikkelen et lokalt og empirisk perspektiv på hvordan og hvorfor muslimske kvinner forholder seg til ulike former for kilder og autoriteter i sin søken etter kunnskap om islam. Videre beskriver den hvordan kvinnene i studiegruppa gjennom å forholde seg aktivt til ulike former for islamsk autoritet, kan operere uavhengig og skape seg en form for uavhengighet fra den lokale moskeen flertallet av kvinnene har institusjonelle bånd til.
Unveiling Hatred
Authors: Gunthel Natalie
Published: May 2023

Although anti-Muslim hate crimes have been on the rise in most Western nations for decades, according to influential hate crime scholar, Barbara Perry, little attention has been given to the particular vulnerability of veiled Muslim females to such crimes (Perry 2013), thereby potentially disregarding a sustained source of human rights violations (Perry and Olsson 2009). This paper delves into Danish sociolegal reality to delineate the scope of such concern, attempting to ascertain any specific hate crime vulnerability among veiled Muslim women in Denmark. It identifies a number of preliminary empirical indications that resonate with Perry’s claim, reasoning that the hate crime vulnerability of veiled women be more thoroughly scrutinized in a Danish context. However, it also argues that such hate crime vulnerability is most productively addressed, at least prima facie, as a tangible and principal human rights issue (Brudholm 2016) rather than in the terms of human rights violations.
Mediation of Muslim Gender Norms
Authors: Amer Nanna Ellen
Published: May 2023

In this article, I examine how religious Muslim actors representing a religious institution and reli-gious Muslim actors who are independent of such institutions mediate Muslim gender norms in online platforms in Denmark, and what modes of argumentation the actors use in their articulation of gender roles and family structures. I find that most of the actors subscribe to traditional gender norms and family structures with the main argument being the natural stature of traditional gender roles. I discuss the fluidity of the religious and secular mediation of the actors, and how the argu-mentation used by the actors challenges secular perceptions of notions such as gender equality and emancipation.
Izmaksas optimizējošs, inovatīvs risinājums pārvades tīkla kapacitāšu pārvaldībai zemas inerces vāji savienotās energosistēmās
Authors:   , Guzs Dmitrijs
Published: May 2023

Saskaņā ar politisko lēmumu sinhronizēt Baltijas energosistēmu (BES) ar kontinentālo Eiropu BES kļūs par vāji savienotu energosistēmu, reizēm strādājošu salas režīmā ar samazinātu inerces līmeni. Tiek piedāvāta jauna prediktīva ātrās atslodzes metode/shēma minēto ar BES sinhronizācijas ar Eiropu saistīto izaicinājumu risināšanai. Piedāvātā metode balstīta sinhrono kompensatoru kā frekvences/frekvences izmaiņu sensoru izmantošanā un spēs palīdzēt stabilizēt energotīkla frekvenci lielo ģenerācijas avotu atslēgumu gadījumā.
A billion years arms-race between viruses, virophages and eukaryotes
Authors: Nino Barreat Jose Gabriel , Katzourakis Aris
Published: May 2023

Bamfordviruses are arguably the most diverse group of viruses infecting eukaryotes. They include the Nucleocytoplasmic Large DNA viruses (NCLDVs), virophages, adenoviruses,
Mavericks
and Polinton-like viruses. Two main hypotheses for their origins have been proposed: the “nuclear-escape” and “virophage-first” hypotheses. The “nuclear-escape” hypothesis proposes an endogenous,
Maverick
-like ancestor which escaped from the nucleus and gave rise to adenoviruses and NCLDVs. In contrast, the “virophage-first” hypothesis proposes that NCLDVs coevolved with protovirophages;
Mavericks
then evolved from virophages that became endogenous, with adenoviruses escaping from the nucleus at a later stage. Here, we test the predictions made by both models and consider alternative evolutionary scenarios. We use a data set of the four core virion proteins sampled across the diversity of the lineage, together with Bayesian and maximum-likelihood hypothesis-testing methods, and estimate rooted phylogenies. We find strong evidence that adenoviruses and NCLDVs are not sister groups, and that
Mavericks
and Mavirus acquired the rve-integrase independently. We also found strong support for a monophyletic group of virophages (family
Lavidaviridae
) and a most likely root placed between virophages and the other lineages. Our observations support alternatives to the nuclear-escape scenario and a billion years evolutionary arms-race between virophages and NCLDVs.
Structure of the connexin-43 gap junction channel in a putative closed state
Authors: Qi Chao , Acosta-Gutierrez Silvia , Lavriha Pia , Othman Alaa , Lopez-Pigozzi Diego , Bayraktar Erva , Schuster Dina , Picotti Paola , Zamboni Nicola , Bortolozzi Mario , Gervasio Francesco L. , Korkhov Volodymyr M.
Published: May 2023

Gap junction channels (GJCs) mediate intercellular communication by connecting two neighboring cells and enabling direct exchange of ions and small molecules. Cell coupling via connexin-43 (Cx43) GJCs is important in a wide range of cellular processes in health and disease 1-3 , yet the structural basis of Cx43 function and regulation has not been determined until now. Here we describe the structure of a human Cx43 GJC solved by cryo-EM and single particle analysis at 2.26 Å resolution. The pore region of Cx43 GJC features several lipid-like densities per Cx43 monomer, located close to a putative lateral access site at the monomer boundary. We found a previously undescribed conformation on the cytosolic side of the pore, formed by the N-terminal domain and the transmembrane helix 2 of Cx43 and stabilized by a small molecule. Structures of the Cx43 GJC and hemichannels in nanodiscs reveal a similar gate arrangement. The features of the Cx43 GJC and hemichannel cryo-EM maps and the channel properties revealed by molecular dynamics simulations suggest that the captured states of Cx43 are consistent with a closed state.
Rubella virus tropism and single cell responses in human primary tissue and microglia-containing organoids
Authors: Popova Galina , Retallack Hanna , Kim Chang N. , Shin David , Wang Albert , DeRisi Joseph , Nowakowski Tomasz J.
Published: May 2023

Rubella virus is an important human pathogen that can cause neurologic deficits in a developing fetus when contracted during pregnancy. Despite successful vaccination programs in the Americas and many developed countries, rubella remains endemic in many regions worldwide and outbreaks occur wherever population immunity is insufficient. Intense interest since rubella virus was first isolated in 1962 has advanced our understanding of clinical outcomes after infection disrupts key processes of fetal neurodevelopment. Yet it is still largely unknown which cell types in the developing brain are targeted. We show that in human brain slices, rubella virus predominantly infects microglia. This infection occurs in a heterogeneous population but not in a highly microglia-enriched monoculture in the absence of other cell types. By using an organoid-microglia model, we further demonstrate that rubella virus infection leads to a profound interferon response in non-microglial cells, including neurons and neural progenitor cells, and this response is attenuated by the presence of microglia.
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain
Authors: Harris Noah J , Jenkins Meredith L , Nam Sung-Eun , Rathinaswamy Manoj K , Parson Matthew AH , Ranga-Prasad Harish , Dalwadi Udit , Moeller Brandon E , Sheekey Eleanor , Hansen Scott D , Yip Calvin K , Burke John E
Published: May 2023

PI3Kγ is a critical immune signaling enzyme activated downstream of diverse cell surface molecules, including Ras, PKCβ activated by the IgE receptor, and Gβγ subunits released from activated GPCRs. PI3Kγ can form two distinct complexes, with the p110γ catalytic subunit binding to either a p101 or p84 regulatory subunit, with these complexes being differentially activated by upstream stimuli. Here using a combination of Cryo electron microscopy, HDX-MS, and biochemical assays we have identified novel roles of the helical domain of p110γ in regulating lipid kinase activity of distinct PI3Kγ complexes. We defined the molecular basis for how an allosteric inhibitory nanobody potently inhibits kinase activity through rigidifying the helical domain and regulatory motif of the kinase domain. The nanobody did not block either p110γ membrane recruitment or Ras/Gβγ binding, but instead decreased ATP turnover. We also identified that p110γ can be activated by dual PKCβ helical domain phosphorylation leading to partial unfolding of an N-terminal region of the helical domain. PKCβ phosphorylation is selective for p110γ-p84 compared to p110γ-p101, driven by differential dynamics of the helical domain of these different complexes. Nanobody binding prevented PKCβ mediated phosphorylation. Overall, this works shows an unexpected allosteric regulatory role of the helical domain of p110γ that is distinct between p110γ-p84 and p110γ-p101, and reveals how this can be modulated by either phosphorylation or allosteric inhibitory binding partners. This opens possibilities of future allosteric inhibitor development for therapeutic intervention.
The hidden depths of zebrafish skin
Authors: Tan Yue Rong , Liaw Megan , Chen Chen-Hui
Published: May 2023

Single-cell transcriptome analysis of zebrafish cells clarifies the signalling pathways controlling skin formation and reveals that some cells produce proteins required for human teeth to acquire their enamel.
Small-fragment, high turnover: soil microenvironment fluctuation effect on tree diversity in a Neotropical montane oak forest
Authors: López-Calvillo Luis F. , Carbó-Ramírez Pilar , Rodríguez-Ramírez Ernesto C.
Published: May 2023

Background

Soil microenvironmental variables showed an important key in α and β-tree diversity in Neotropical montane oak forest. Thus, understanding the microenvironment fluctuation at small-fragment effects on tree diversity is crucial in maintaining the montane oak ecosystems. In this study, we hypothesized that within a relatively small-fragment (151.63 ha), tree α and β-diversity fluctuate and specific soil microenvironmental factors could influence tree species diversity to answer three questions: Do tree α and β-diversity differ among transects, even in a short-distance between them? Do microenvironmental variables influence tree diversity composition that occurs within a relict Neotropical montane oak forest? Is there a particular microenvironmental variable influencing tree species-specific?

Methods

We established four permanent transects during a year in a relict Neotropical montane oak forest, we assessed tree diversity and specific microenvironmental variables (soil moisture, soil temperature, pH, depth litterfall and light incidence). This allowed us to evaluate how microenvironmental variables at small-fragment influence α and β-tree diversity and tree species-specific.

Results

Our results showed that α-diversity was not different among transects; however, β-diversity of tree species was mostly explained by turnover and soil moisture, soil temperature, and light incidence were the microenvironmental variables that triggered the replacement (i.e., one species by another). Those variables also had effect on tree species-specific: Mexican beech (Fagus mexicana), Quebracho (Quercus delgadoana), Pezma (Cyathea fulva), Aguacatillo (Beilschmiedia mexicana), Pezma (Dicksonia sellowiana var. arachneosa), and Mountain magnolia (Magnolia schiedeana).

Discussion

Our results confirm our hypothesis related to β-diversity but not with α-diversity; however, the tree community structure of the diversity was similar among transects. Our study represents the first effort to evaluate and link the soil microenvironmental effect on tree α and β-diversity, finding a high replacement in a small-fragment of Neotropical montane oak forest from eastern Mexico.
Urbanismo de proximidad en Barcelona. Una ciudad saludable a 15 minutos del hogar
Authors: Sansão Fontes Adriana , Espósito Fernando
Published: May 2023

Desde diciembre de 2019, ciudades de todo el mundo han sido impactadas por la pandemia del COVID-19, enfermedad que se expandió rápidamente gracias a su facilidad de transmisión por contacto directo entre personas, situación que ha impuesto un distanciamiento físico como medida para minimizar su propagación. En ese contexto, gobiernos han sido desafiados a pensar soluciones para garantizar el uso de los espacios públicos de forma segura durante la pandemia. Este artículo observa una relación contemporánea entre ciudad y salud, presentando tres casos en la ciudad de Barcelona: el sistema de patios internos de manzana del Ensanche, el programa Superilles y las medidas locales de emergencia en respuesta al COVID-19. En esos casos es posible percibir el papel que juega el espacio público en una ciudad saludable, como parte de las estrategias de respuesta a la pandemia. Metodológicamente, el trabajo articula investigación en campo, referencial teórico-conceptual y referencial bibliográfico de los casos, esos últimos como soporte de la discusión. En esa coyuntura socio espacial, de importantes desafíos para la planificación de las ciudades, se revela el urbanismo de proximidad: una ciudad de menores desplazamientos y mayor diversidad de espacios y servicios a 1 Km de distancia de los hogares.
End of the progressive cycle, resurgence of the "new right" and foreign policy action for regionalism in governments of Brazil, Argentina and Chile (2019)
Authors: Pasquarelli Bruno Vicente Lippe
Published: May 2023

In Brazil, Argentina and Chile, the resurgence of the "new right" took place with a discourse based on distrust of the parties and of politics itself and with the emphasis on the need for less state action and the privilege of market mechanisms. Based on these considerations, through a discourse analysis methodology to understand the interests that the actors defend and the implications of political discourse marked by specific constructions and subjectivities, the study examines whether the new right has had new directions in foreign policy aimed at regional integration in South America, highlighting what have been the positions of these new governments. To achieve these objectives, the causes of the emergence of the new right will be investigated in each of the contexts, highlighting the political system, societal and economic aspects. An analysis will then be made of the main guidelines for the election of the new right in terms of foreign policy, verifying the existence of regional integration policies in government programs. Finally, the study considers the position taken by the Ministries of Foreign Affairs and the President of each country, analyzing official documents and speeches on social networks.
Phytochemical Properties and Hypoglycemic Effect of Finger Millet Malt Drinks Supplemented with Cucumber and Carrot Juice on Alloxan-Induced Diabetic Rats
Authors: Onwurafor Eucharia U. , Iloka Chinonyelum I. , Uzodinma Eunice O. , Aronu Chinwe J. , Aniagor Ebele N.
Published: May 2023

Aim: The study evaluated the phytochemical content and effect of supplementation of finger millet malt drinks with 25% carrot and cucumber juice on diabetes management.

Sample: Finger millet malt, cucumber juice, carrot juice, Albino rats.

Study Design: Completely Randomized Design was used.

Place and Duration of Study: Department of Food Science and Technology and Department of Animal Health and production, Faculty of veterinary Medicine, University of Nigeria, Nsukka (between January 2021 and June, 2021.

Methodology: Finger millet grain was malted for 48 h, dried for 5 days, and subsequently divided into two portions. A portion was roasted while the other was not. Roasted and unroasted finger millet malt drinks were prepared and blended in different ratio with processed mixture of carrot and cucumber juice. The finger millet malt drink and the supplemented malt were evaluated for phytochemical and microbial properties using standard methods. Thirty albino rats separated into four test groups and one control group initially tested for fasting blood glucose were induced diabetes using Alloxan monohydrate (dose=150 mg/kg body weight). The test animals were fed malt drinks and measured amount of rat chow for 28 days, their blood samples were subjected to serum lipid profile, fasting blood sugar and weight measurement.

Results: The results revealed that the total phenols and flavonoids increased with supplementation with cucumber and carrot juice. Total viable counts of the malt drinks ranged from 1.13 -2.93 x 102Cfu/100ml and no mould growth was detected. Rats fed sample prepared from 50% unroasted finger millet malt drink, 25% of cucumber and 25% carrot juice) had the highest reduction in fasting blood sugar level (87% and also most effective in weight regain(15.30%) while rats fed 100% roasted finger malt drink had the least decrease in fasting blood sugar (44.2%). High density lipoprotein increased and the values ranged from 26.00 -50.34 mg/dl while cholesterol, very low-density lipoprotein, low-density lipoprotein, and triglyceride levels reduced and the values ranged from 16.17 to 42.28, 8.17 -9.16, 13.35 – 21.44 and 40.84 – 46.64 mg/dl, respectively in the rats fed experimental malt drink.

Conclusion: Rats fed samples containing 50% unroasted finger millet malt, 25% of cucumber and 25% carrot drink had more weight gain (15.30%) and fasting blood glucose reduction (87%). Malted drinks from unroasted finger millet enriched with cucumber and carrot juice can be used in diabetes management.
Perception of Work Ethics and Professionalism on Work Output of Hall Assistants at the University of Education, Winneba, Ghana
Authors: Ananga Patricia
Published: May 2023

This paper explored the perspectives of hall assistants at the four halls of residence of the University of Education, Winneba regarding work ethics and professionalism, and how their knowledge of these concepts affects their work output. Work ethics and professionalism cannot be fully dealt with without giving due diligence to public protection and the provision of public services. The paper employed social constructivism as a theory to understand how hall assistants construct their own meaning of professionalism and work ethics and how their knowledge of these translates into influencing their work output. The qualitative exploratory case study design, with the use of a semi-structured interview guide to obtain data, was adopted.  Purposive and convenience sampling techniques were used to collect data from twelve (12) respondents at the University of Education, Winneba. The key findings of the study revealed that when employees show traits such as good attitude, team spirit, and credibility in the way they carry themselves, it influences the work they do and eventually yields high productivity. The study concluded with implications of the findings for policy on the relevance of professionalism and work ethics on increased output of work.