bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Program Moderasi Beragama di Madrasah Tsanawiyah Negeri 5 Kulon Progo
Authors: Ismunandar
Published: May 2024

Tujuan – Penelitian ini menginvestigasi pengembangan dan implementasi program moderasi beragama di Madrasah Tsanawiyah Negeri 5 Kulon Progo, Indonesia, berdasarkan Keputusan Menteri Agama No. 184 tahun 2019. Tujuan utama studi ini ada tiga: 1) Menganalisis pengembangan program moderasi beragama di sekolah tersebut, 2) Meneliti peran administrator sekolah, pendidik, dan siswa dalam pelaksanaan program ini, dan 3) Mendeskripsikan metodologi yang digunakan dalam pengembangan program moderasi beragama.
Metode – Penelitian ini mengikuti kerangka Riset dan Pengembangan (R&D), menggunakan model sepuluh tahap Borg dan Gall. Teknik pengumpulan data dalam penelitian tindakan kelas ini adalah dengan teknik tes, wawancara, dan dokumentasi. Analisis data menggunakan statistik deskriptif.
Hasil – Program ini mencakup modul "Kita semua Saudara (KISA)," "Aku Cinta Indonesia (ACI)," "Hormati Budaya Lokal (HBL)," dan "Sabtu Muqodaman Al Aquran (SAMAN)." Keterlibatan aktif semua pemangku kepentingan sekolah secara signifikan berkontribusi pada keberhasilan pelaksanaan program. Selain itu, pengembangan program untuk pengajaran Akidah Akhlak di kelas delapan menunjukkan tingkat validitas yang wajar berdasarkan validasi ahli, uji pengguna terbatas, dan uji coba utama. Lebih lanjut, efektivitas program dalam meningkatkan kinerja siswa kelas delapan sebelum dan setelah pelaksanaannya secara statistik signifikan. Implikasi studi ini melampaui konteks khusus, membahas peran penting lembaga pendidikan dalam memupuk moderasi beragama. Keberhasilan pelaksanaan, yang dipandu oleh Keputusan Menteri Agama No. 184 tahun 2019, menjadi model bagi lembaga pendidikan lainnya, mempromosikan toleransi, penghormatan terhadap keragaman, dan kehidupan bersama yang damai dalam lanskap budaya dan agama yang beragam di Indonesia. Namun, penting untuk mengakui keterbatasan studi ini dan merekomendasikan penelitian lebih lanjut di bidang ini untuk menjelajahi dimensi dan konteks tambahan, meningkatkan pemahaman kita tentang moderasi beragama dan dampaknya pada masyarakat
Lasers nunca foram tão FATO
Authors: Aranha Ana Cecilia
Published: May 2024

Se existe algo que eu gosto de fazer, escrever e ensinar sobre, é o uso do laser em Odontologia. Assim, não poderia começar essa coluna sem trazer para discussão uma tecnologia que eu pesquiso, uso e ensino há 23 anos.
Arquitetura e decoração na Odontologia
Authors: Soares Michelle Mundim , Rodrigues Tarcília
Published: May 2024

Uma conexão vital para a experiência do paciente e na eficácia operacional do consultório. A escolha meticulosa do visual da clínica desempenha um papel significativo na construção da marca. O alinhamento na elaboração de um projeto arquitetônico e de decoração para um consultório odontológico transcende a mera estética, desempenhando um papel vital na eficácia operacional e na experiência geral dos pacientes. Ao contemplar a disposição dos espaços, pode-se otimizar não apenas o fluxo de pessoas, mas também garantir a eficiência no uso de equipamentos odontológicos específicos. Ressaltamos também a grande importância de estar atualizado com as exigências dos estabelecimentos de saúde da sua região, levando em consideração suas orientações.
Stochastic Mixed-Integer Branch Flow Optimization for the Optimal Integration of Fixed-Step Capacitor Banks in Electrical Distribution Grids
Authors: Gil-González Walter Julián , Herrera-Orozco Andrés Ricardo , Molina-Cabrera Alexander
Published: May 2024

Context: The use of capacitor banks is the most common and preferred solution for reducing power loss in electrical distribution networks, given their cost-effectiveness and low maintenance requirements. However, achieving their optimal integration in terms of location and size is a challenging problem. Method: This paper proposes a stochastic mixed-integer convex model based on a branch flow optimization model, which incorporates three different load-generation conditions, in order to address the stochastic nature of distribution systems.Results: The simulation results indicated that the proposed stochastic mixed-integer branch flow (SMIBF) model provides the best solution for all test feeders analyzed, reducing the objective function value by 39.81%, 35.29%, and 56.31% for the modified 33-, 69-, and 85-node test feeders, respectively.Conclusions: An SMIBF model was developed to optimally integrate fixed-step capacitor banks into electrical distribution grids. This model considered the stochastic nature of distribution systems under multiple operating conditions and ensured that the global optimum could be found.
Network for the Large-Scale Integration of Renewable Energies in Electrical Systems (RIBIERSE-CYTED, 723RT0150): Results for 2023
Authors: Medina-Quesada María Ángeles , Serra Federico Martin , Baier-Fuentes Carlos Rodrigo , Montoya-Giraldo Oscar Danilo , Soares Joao André Pinto , França Bruno Wanderley , Andrade-Rengifo Fabio , Hernández Jesús de la Casa
Published: May 2024

The RIBIERSE-CYTED network, i.e., the network for the large-scale integration of renewable energies in electrical systems (723RT0150) (2023-2026) is a hub for researchers and technologists belonging to Ibero-American universities, companies, and local administrations. This network promotes cross-training, mobility between centers, and the dissemination and implementation of technical and training activities aimed at analyzing and developing opportunities for the maximal integration of renewable resources, seeking a more sustainable energy model while allowing for the increased use of renewable resources and electric mobility (e-mobility).
Spatial Analysis of Environmental Factors in the Dengue Hemorrhagic Fever Incident at Soe City District
Authors: Bakung Paulus Innocentius , Landi Soleman , Sir Amelya B
Published: May 2024

Introduction: In 2022, there was a large increase in cases resulting in extraordinary events cases in the TTS district with the number 226 cases. Half of the percentage of outbreak cases that occurred in Soe City with a number of cases is 134 cases. Spatial analysis can be used to see patterns of disease distribution in certain areas.Methods: This research is a type of descriptive research with a case study approach. This descriptive research was carried out using a survey method where there was no intervention on variables but simply observing natural phenomena or looking for relationships between these phenomena and other variables.Results:  The research of dengue case data is divided into univariate analysis and spatial analysis, for example, classification, buffering and Moran index. Environmental factors in the form of the existence and condition of water reservoirs with dengue fever incidents can be seen in data related to the number of water reservoirs used by the community which are left open and the number is >3, making it easier for mosquitoes to breed. In the Spatial Classification Analysis, Nonohonis Village has the highest level of risk, but Autocorrelation Analysis states that the Oekefan area has larger cluster points than Nonohonis Village. Furthermore, environmental factors include the existence and condition of dug wells. at a depth of ≤15m with open conditions makes it easier for mosquitoes to breed. Apart from that, based on the buffer data above, it can be seen that at a radius of <100m it is 3 times larger than a radius of 100 to 300m and 2.7 times larger than a radius of 300m to 500m. Environmental factors include the existence and condition of waste water drainage channels (SPAL) with dengue fever incidents. Based on the buffer data above, it can be seen that at a radius of <100m it is 0.6 times greater than the radius from 100 to 300m and 0.8 times greater than the radius from 300m to 500m.Conclusion: It is necessary to control mosquito breeding in water reservoirs and dug wells through education regarding malaria risk factors in Soe City.
The Relationship Between Working Posture and Musculoskeletal Disorders in Waste Pickers at Blondo Landfill
Authors: Heryanda Annisa Putri , Lestari Sri
Published: May 2024

Abstract Background: Blondo landfill serves as a final processing site for waste and also a source of livelihood for scavengers. Scavengers are workers who are at risk of musculoskeletal disoders (MSDs) complaints due to heavy, repetitive physical work and poor work postures due to bending. During waste collection and sorting, waste pickers perform repetitive movements with non-ergonomic postures, away from the ideal body position. Based on data from Puskesmas Bawen, 45% of 73 waste pickers experienced muscle and joint pain. The purpose of this study was to determine the relationship between working posture and complaints of musculoskeletal disorders.Methods: This study was an observational analytic research in a cross sectional design. The population in this study were Blondo landfill waste pickers. The subjects were 65 waste pickers who were chosen through purposive sampling technique. Data collection was conducted through interviews using the Nordic Body Map questionnaire, digital camera and REBA (Rapid Entire Body Assessment) sheet. Data analysis were conducted using Spearman rank tests.Results: The results showed that of the 65 waste pickers, the majority were female (53.3%), aged > 35 years (93.8%), had a working period of more than 5 years (61.5%), and normal nutritional status (56.9%). Scavengers who have moderate risk work posture (81.5%) and moderate musculoskeletal disorders (84.6%). There was a positive correlation between working posture and MSDs with a moderate level (ρ=0.593; p=0.0001).Conclusion: Work postures that are formed away from the body's gravity which if done continuously and for a long period of time among waste pickers resulted in musculoskeletal disorders.
Problém reflexivity
Authors: Chaloupková Lucie
Published: May 2024

This article presents reflexivity in its various meanings and forms as it appears in anthropology and social sciences. During the second half of the twentieth century in these fields, it became both an inspiration for various theories of the functioning of social phenomena, but also a part of anthropological methodology: in the era of the reflexive turn, it served as a critique of the situatedness of the production of anthropological knowledge, which was supposed to unmask the personal influence of the researcher on the resulting form of the texts. Although the contribution of this stage to the understanding of the meaning of the textuality of anthropological works cannot be denied, I see its “normalization” as part of anthropological methodology as problematic. If we focus more closely on the functioning mechanisms of reflexivity and self-reflection, we will come across certain paradoxes. In this paper, I focus on various criticisms of reflexivity, through which I try to approach the essence of the problem of using reflexivity. Emphasis is placed on the debate on reflexivity as a pivotal mechanism in the organization of late modern societies as described by theorists such as Giddens, Beck, Lash or Archer. These theories are confronted with the concept of “speech” as understood by constructivist approaches such as discourse analysis, which view all meanings as variable and constantly constructed by linguistic means in ordinary speech. I further show how reflexivity is unmasked by the opponents of reflexive modernization theory as a rhetorical strategy used to legitimize the status quo. This example serves as an illustration of the illusory nature of reflexivity and the possibility of its misuse.
Luděk Jirka: Rivnenská oblast a její menšiny. O historii etnických vztahů na území bývalé Volyně.
Authors: Jakoubek Marek
Published: May 2024

A review of a book by Marek Jakoubek.
Capturing More Associations by Referencing External Graphs
Authors: Fan Wenfei , Liu Muyang , Liu Shuhao , Tian Chao
Published: May 2024

This paper studies association rule discovery in a graphG1by referencing an external graphG2with overlapping information. The objective is to enrichG1with relevant properties and links fromG2. As a testbed, we consider Graph Association Rules (GARs). We propose a notion of graph joins to enrichG1by aligning entities acrossG1andG2. We also introduce a graph filtering method to support graph joins, by fetching only the data ofG2that pertains to the entities ofG1, to reduce noise and the size of the fused data. Based on these we develop a parallel algorithm to discover GARs acrossG1andG2. Moreover, we provide an incremental GAR discovery algorithm in response to updates toG1andG2. We show that both algorithms guarantee to reduce parallel runtime when given more processors. Better yet, the incremental algorithm is bounded relative to the batch one. Using real-life and synthetic data, we empirically verify that the methods improve the accuracy of association analyses by 30.4% on average, and scale well with large graphs.
Influence Maximization via Vertex Countering
Authors: Xie Jiadong , Chen Zehua , Chu Deming , Zhang Fan , Lin Xuemin , Tian Zhihong
Published: May 2024

Competitive viral marketing considers the product competition of multiple companies, where each user may adopt one product and propagate the product to other users. Existing studies focus on a traditional seeding strategy where a company only selects seeds from the users with no adopted product to maximize its influence (i.e., the number of users who will adopt its product). However, influential users are often rare, and the gain from traditional seeding will degrade as the number of seeds increases. Therefore, in this paper, we study the promisingcounteringstrategy which is to counter some users who initially use other products s.t. they will turn to adopting the target product and recommending it to others.

We propose the problem ofinfluence countering: given a graph, a budgetb, a target companyCt, and a setSof the seeds adopting different companies (where each seed adopts one company), we counterbusers inSwho do not adoptCtto turn to adoptCts.t. the expected number of users who eventually adoptCtin the influence diffusion is maximized. Following existing studies, we formalize the diffusion process by the Multi-Campaigner Independent Cascade model. We prove the influence countering problem is #P-complete and its influence computation is #P-hard. Then, we propose two novel algorithmsMICandMIC+to address the problem. In general,MICestimates seed influence by its empirical average influence in multiple graph samplings, whileMIC+improvesMICby reducing the cost of influence estimation and the required number of samples. Given pre-setεandl, both algorithms return a (1 -ε)-approximate solution with at least 1 -n-lprobability. We also design an index forMIC+to efficiently process graphs that are frequently updated. The experiments on 8 real-world datasets show that our algorithms are efficient in practice while offering strong result quality.
Efficient Placement of Decomposable Aggregation Functions for Stream Processing over Large Geo-Distributed Topologies
Authors: Chatziliadis Xenofon , Zacharatou Eleni Tzirita , Eracar Alphan , Zeuch Steffen , Markl Volker
Published: May 2024

A recent trend in stream processing is offloading the computation of decomposable aggregation functions (DAF) from cloud nodes to geo-distributed fog/edge devices to decrease latency and improve energy efficiency. However, deploying DAFs on low-end devices is challenging due to their volatility and limited resources. Additionally, in geo-distributed fog/edge environments, creating new operator instances on demand and replicating operators ubiquitously is restricted, posing challenges for achieving load balancing without overloading devices. Existing work predominantly focuses on cloud environments, overlooking DAF operator placement in resource-constrained and unreliable geo-distributed settings.

This paper presents NEMO, a resource-aware optimization approach that determines the replication factor and placement of DAF operators in resource-constrained geo-distributed topologies. Leveraging Euclidean embeddings of network topologies and a set of heuristics, NEMO scales to millions of nodes and handles topo-logical changes through adaptive re-placement and re-replication decisions. Compared to existing solutions, NEMO achieves up to 6× lower latency and up to 15× reduction in communication cost, while preventing overloaded nodes. Moreover, NEMO re-optimizes placements in constant time, regardless of the topology size. As a result, it lays the foundation to efficiently process continuous data streams on large, heterogeneous, and geo-distributed topologies.
Decay estimates for defocusing energy-critical Hartree equation
Authors: Chen Miao , Wang Hua , Yao Xiaohua
Published: May 2024

In this paper, we are devoted to establishing the point-wise decay estimates for solution to the 5D defocusing energy-critical Hartree equation with an initial data in

H

2

(

R

5

)

∩

L

1

(

R

5

)

${H}^{2}({\mathbb{R}}^{5})\cap {L}^{1}({\mathbb{R}}^{5})$

. We show that the nonlinear solution has the same time decay rate as the linear one. The main new ingredient is that we used the theories of Lorentz spaces to overcome the low power of nonlinearity.
The Swiss Debt Brake Is Democratic, Strict, Transparent, and Binding. A Model to Follow?
Authors: Mosler Martin , Schaltegger Christoph
Published: May 2024

The Swiss debt brake at the federal level was accepted in 2001 by a direct democratic referendum, where it received an overwhelming approval rate of almost 85 percent “yes” votes. The fiscal rule mandates that budgeted expenditures cannot exceed cyclically adjusted expected revenues, targeting gross debt while prohibiting new structural debt. Violations due to ordinary or extraordinary expenditures are transparently recorded in separate accounts, which must be balanced within three and six years, respectively. The federal rule is complemented by decentralized debt brakes at the cantonal level. Compared to a synthetic Switzerland without the federal debt brake, the fiscal rule did not decrease public investments, with the notable exception of military expenditure. Additionally, the accuracy of budget forecasts has improved, evidenced by reduced discrepancies between projected and actual revenues and expenditures.
Effect of dopamine on limbic network connectivity at rest in Parkinson’s disease patients with freezing of gait
Authors: Quek Dione Y. L. , Taylor Natasha , Gilat Moran , Lewis Simon J. G. , Ehgoetz Martens Kaylena A.
Published: May 2024

Background

Freezing of gait (FOG) in Parkinson’s disease (PD) has a poorly understood pathophysiology, which hinders treatment development. Recent work showed a dysfunctional fronto-striato-limbic circuitry at rest in PD freezers compared to non-freezers in the dopamine “OFF” state. While other studies found that dopaminergic replacement therapy alters functional brain organization in PD, the specific effect of dopamine medication on fronto-striato-limbic functional connectivity in freezers remains unclear.

Objective

To evaluate how dopamine therapy alters resting state functional connectivity (rsFC) of the fronto-striato-limbic circuitry in PD freezers, and whether the degree of connectivity change is related to freezing severity and anxiety.

Methods

Twenty-three PD FOG patients underwent MRI at rest (rsfMRI) in their clinically defined “OFF” and “ON” dopaminergic medication states. A seed-to-seed based analysis was performed between a priori defined limbic circuitry ROIs. Functional connectivity was compared between OFF and ON states. A secondary correlation analyses evaluated the relationship between Hospital Anxiety and Depression Scale (HADS)-Anxiety) and FOG Questionnaire with changes in rsFC from OFF to ON.

Results

PD freezers’ OFF compared to ON showed increased functional coupling between the right hippocampus and right caudate nucleus, and between the left putamen and left posterior parietal cortex (PPC). A negative association was found between HADS-Anxiety and the rsFC change from OFF to ON between the left amygdala and left prefrontal cortex, and left putamen and left PPC.

Conclusion

These findings suggest that dopaminergic medication partially modulates the frontoparietal-limbic-striatal circuitry in PD freezers, and that the influence of medication on the amygdala, may be related to clinical anxiety in freezer.
Die ökonomische Bedeutung des Brexits
Authors: Lee Andrew
Published: May 2024

On January 1, 2021, Great Britain (England, Scotland and Wales) left the EU single market and customs union. Although the Trade and Cooperation Agreement between the UK and EU ensures that no tariffs or quotas are to be imposed on traded goods, there are still numerous non-tariff barriers to trade. These added a significant layer of trade complexity that did not exist pre-Brexit and it was thus inevitable that there would be ramifications for the UK economy. Carefully judging this impact is a complicated task, however, as a counterfactual must be used: how would the UK economy have fared if it were still in the EU? This difficulty is exacerbated by two other highly significant events affecting the UK economy at the same time, namely the Covid-19 pandemic and the Ukraine war. Disentangling Brexit from all this and deciding what is and is not a Brexit effect makes the evaluation thereof difficult. Nevertheless, there have been a number of studies published that have attempted such a task.

UK-EU trade is widely judged to have taken a significant hit due to Brexit, with smaller firms producing a limited range of products being affected the most. The consensus view is that Brexit has also had a negative impact on UK investment levels and GDP, with the latter judged to be approximately 6 % lower than if the UK had stayed in the EU. In the long run, the UK economy may benefit from more skilled foreign labour due to the post-Brexit immigration rules. Nevertheless, any positive effects are likely to be outweighed by the non-tariff barriers in UK-EU trade, acting as a deterrent in exploiting comparative advantage and widely seen as being the main drag on UK productivity.
Steigende Staatsquote oder schwarze Null – ein theoretischer Erklärungsansatz durch öffentliche Güter
Authors: Volpert Tobias , Rasfeld Sophie
Published: May 2024

The German national deficit reached an unprecedented magnitude following the COVID-19 pandemic. Consequently, determining an appropriate or correct public sector share has become the subject of extensive discourse. A crucial theoretical explanatory approach for the increasing intervention of the state is the theory of public goods. This article elucidates why markets are unsuitable for the production of certain goods, commonly referred to as public goods. Furthermore, the article demonstrates, through the elucidation of impure public goods, that the state undertakes tasks that could be handled by the market itself. Therefore, it is essential to question why the state produces specific goods, particularly in light of Germany’s saving goals.
Insecticidal effect of new synthesized chalcone derivatives on Caribbean fruit fly, Anastrepha suspensa
Authors: Yücetepe Sümeyye , Koçyiğit-Kaymakçıoğlu Bedia , Yang Xiangbing , Tabanca Nurhayat , Tok Fatih
Published: May 2024

In this present study, new chalcone derivatives were synthesized from 4-aminoacetophenone, which were confirmed by spectroscopic methods. The toxic risks of chalcones to humans and the environment were investigated by a web-based platform called ADMETlab. With this program, the possible toxic effects of the compounds on liver, respiratory system, and eyes were evaluated. For the topical insecticidal activity, adult female Caribbean fruit fly, Anastrepha suspensa, was targeted. Results of the toxicity tests showed that chalcone derivatives are effective against female A. suspensa. Among the synthesized chalcones, 1-(4-cinnamoylphenyl)-3-(p-tolyl)urea (2) exhibited the greatest insecticidal activity, resulting in 73 % mortality at 100 µg/fly after 24 h, whereas other derivatives showed less than 30 % mortality. Our results demonstrate that insecticidal activity may be modulated by the presence of a certain phenyl ring in the structure of derivative 2 and, therefore, has potential for design of efficient chemicals for tephritid fruit fly management.
Current Outcomes after Revascularization for Coronary Very Late Stent Thrombosis
Authors: Hou Yunqing , Gu Yan , Wu Muli , Zheng Yang , Chen Xinxin , Wang Xiang
Published: May 2024

Objective: Limited data are available regarding current outcomes after revascularization for angiographically confirmed very late stent thrombosis (VLST). Therefore, this study investigated the current outcomes of patients with VLST and the risk factors for major adverse cardiovascular events (MACE).

Methods: Consecutive patients who underwent revascularization for angiographically confirmed VLST between January 2014 and January 2016 were enrolled in this study. The patients were divided into two groups according to the occurrence of MACE during follow-up. The clinical and interventional parameters between groups were compared.

Results: A total of 564 patients with an average age of 61.61 ± 10.71 years were enrolled. Eight patients died during hospitalization. MACE occurred in 100 patients after a mean follow-up of 620 days. The total MACE rate was 35.46%, and Kaplan-Meier survival analysis indicated an estimated MACE-free survival rate of 22%. Multivariable Cox regression analysis revealed that left ventricular ejection fraction and peak troponin I at VLST onset were independent predictors of MACE.

Conclusions: Long-term outcomes after revascularization for VLST remained unfavorable. Left ventricular ejection fraction and peak troponin I at the onset of VLST were independent risk factors for poor prognosis.
Molecular Docking, Dynamics Simulation, And in Silico DFT Studies Of Bromo [1,4] Benzodiazepine Derivatives Are Efficient Ways to Prevent Skin Cancer
Authors: Brindha B. , Girija R.
Published: May 2024

Studies have revealed that the most common kind of cancer in the world is skin cancer.  Unrepaired deoxyribonucleic acid (DNA) in skin cells can cause genetic abnormalities or mutations that lead to skin cancer. Early detection is crucial because skin cancer is more treatable in its early stages and tends to gradually spread to other areas of the body. Early detection of signs of skin cancer is essential due to the high mortality, increasing morbidity and expensive medical care of the disease. The present study used ligand and structure-based analysis to calculate the interaction between bromo [1,4] benzodiazepine derivatives and 4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for Cancer. Qikprop revealed that the structures of several antiviral drugs were identical to those of bromo[1,4] benzodiazepine derivatives (1a-1j). bromo [1,4] benzodiazepine derivatives were employed in an in silicodocking experiment, DFT calculations and simulation techniques on skin cancer with PDB ID 2VCI, using Schrodinger Maestro 12.4. Each ligand's interaction was studied, and the potential imperative energy was calculated. In summary, a high potency against skin cancer as observed for the derivative of bromo [1,4] benzodiazepine derivatives with the best binding energy.
Revolutionizing mental health care: exploring the potential of digital mediation in public health
Authors: Peña Jesús Goenaga , Sánchez Mauricio Bonilla
Published: May 2024

This article addresses the concept of digital public health and explores its application in the field of mental health, focusing on technology mediation as a potential tool to improve care and well-being of individuals. Scientific evidence shows that technological mediation in mental health can have a positive and significant impact on patient outcomes. However, it highlights the importance of addressing equitable access to these digital interventions and collaboration between users and mental health professionals in the design and development of effective solutions. The case of the company Saluta, a digital health center that has led several innovations in mental health through accessible and quality digital platforms, is presented. Finally, strategies are proposed to evaluate the impact of technological mediation in digital health care, including constant monitoring of results, research with solid scientific evidence, and the involvement of users in the design and evaluation process.
Advance Care Planning for Children With Rare Diseases: A Pilot RCT
Authors: Lyon Maureen E. , Fraser Jamie L. , Thompkins Jessica D. , Clark Heidi , Brodie Nicola , Detwiler Kathryn , Torres Clarivet , Guerrera Michael F. , Younge Tamiko , Aoun Samar , Trujillo Rivera Eduardo A.
Published: May 2024

BACKGROUND AND OBJECTIVE

Pediatric rare diseases are often life-limiting conditions and/or require constant caregiving. Investigators assessed the initial efficacy of the FAmily CEntered (FACE) pediatric advance care planning (pACP), FACE-Rare, intervention on families’ quality of life.

METHODS

A pilot-phase, single-blinded, intent-to-treat, randomized controlled clinical trial enrolled families from 1 pediatric quaternary hospital between 2021 and 2023. Intervention families received 3 weekly 60-minute (FACE-Rare pACP) sessions: (1) Carer Support Needs Assessment Tool or Action Plan, (2) Carer Support Needs Assessment Tol Action Plan Review, and (3) Pediatric Next Steps: Respecting Choices pACP. Controls received treatment as usual (TAU). Outcome measures were Beck Anxiety Inventory, Family Appraisal of Caregiving, Functional Assessment of Chronic Illness Therapy (FACIT)-Spirituality, and health care utilization. Generalized mixed effect models with γ response assessed the intervention effect at 3-month follow-up.

RESULTS

Children (n = 21) were aged 1 to 10 years, 48% male, 24% Black; and 100% technology dependent. Primary family caregivers (n = 21) were aged 30 to 43 years, 19% male, 19% Black; and 27% household income below the Federal poverty level. Dyads underwent 1:1 randomization: 9 to FACE-Rare and 12 to TAU. TAU caregivers reported statistically lower meaning and peace than FACE-Rare caregivers (0.9, P = .03, confidence interval [CI]: 0.75–0.99). Black caregivers reported significantly less caregiver distress (0.7, P = .04, CI: 0.47–0.98) than non-Black caregivers. Poor families reported more anxiety (3.5, P = .002, CI: 1.62–7.94), more caregiver strain (1.2, P = .006, CI: 1.07–1.42); and less family well-being (0.8, P = .02, CI: 0.64–0.95).

CONCLUSIONS

FACE®-Rare was feasible, acceptable, safe, and demonstrated initial efficacy, providing greater feelings of meaning and peace to caregivers. Poverty impacted well-being. A multisite trial is needed to determine generalizability.
El proemato: Un género híbrido
Authors: Chaverri Hernández Jorhan
Published: May 2024

El objetivo de este trabajo es presentar y justificar el proemato como un género literario híbrido a partir de distintas posturas literarias, mediante el análisis y comparación de algunos textos poéticos y de narrativa breve con los proematos del escritor costarricense Jorhan Chaverri. Se establecen características que permiten diferenciar los proematos de otros géneros y estilos de escritura literaria, lo que sustenta la conclusión de que ese trata de un género (híbrido) que surge de la combinación entre la poesía, la narrativa y el microrrelato, pero a la vez se distingue de ellos.
PERCERAIAN PADA NEGARA MUSLIM: PERBANDINGAN PERUNDANG-UNDANGAN INDONESIA DAN PAKISTAN
Authors: Sulistiawati Nira , Afriadi Wawan
Published: May 2024

Penelitian ini untuk mengetahui persamaan dan perbedaan Hukum Keluarga di Negara Islam tentang perceraian dengan perbandingan antara Indonesia dan Pakistan. Penelitian ini secara umum bertujuan untuk melihat pengaplikasian hokum keluarga Islam tentang perceraian yang berbeda di setiap Negara Muslim tersebut. Adapun metodologi penelitian dalam penulisan isi adalah library research dengan mencari dan mengumpulkan artikel-artikel yang mendukung dengan masalah yang penulis kaji. Hasil penelitian ini menunjukkan bahwa ada perbedaan dan persamaan terhadapa ketentuan percerain di dalam ketentuan perundang-undangan masing-masing negara, ini tidak terlepas dari sosial kultur serta sejarah terbentuknya hukum keluarga Islam di Indonesia dan Pakistan.
Determination of significant diagnostic criteria for the development of primary open-angle glaucoma based on a comprehensive statistical analysis of biomechanical and hemodynamic parameters of the eye
Authors:   Helmholtz National Medical Research Center of Eye Diseases, Iomdina Elena , Kornikov Vladimir ,   Saint-Petersburg University, Bauer Svetlana ,   Saint-Petersburg University, Khoziev Daniel ,   Helmholtz National Medical Research Center of Eye Diseases, Moiseeva Irina ,   Lomonosov Moscow State University, Stein Alexander ,   Lomonosov Moscow State University, Luzhnov Peter ,   Bauman Moscow State Technical University
Published: May 2024

A complex statistical (correlation, discriminant, factorial) analysis of a set of parameters - biomechanical characteristics of the corneoscleral shell of the eye, hemodynamic parameters and perimetric indices, determined during examination of 110 eyes, including 69 eyes with various stages of primary open-angle glaucoma (POAG) and 41 eyes without ophthalmopathology – was carried out. Significantly correlated parameters characteristic of a particular stage of POAG were identified. The set of identified correlations characterizes progressive glaucoma damage as a process associated with a simultaneous change in the biomechanics of the eye shells and the scleral lamina cribrosa, as well as the blood supply to the choroid and retina, which, apparently, underlies the gradual deterioration of its photosensitivity and changes in the visual field. It was found that correlations within groups of patients with various stages of POAG change significantly with the progression of glaucomatous process, and, possibly, reflect the change in the contribution of biomechanical and hemodynamical disorders to the development of glaucomatous lesion at the corresponding stage of its development.
A stochastic model of cell transformations at bone tissue regeneration
Authors:   Ivanovo State Power Engineering University named after V.I. Lenin, Mitrofanov Andrey , Maslov Leonid ,   Ivanovo State Power Engineering University named after V.I. Lenin,   Peter the Great St. Petersburg Polytechnic University, Mizonov Vadim ,   Ivanovo State Power Engineering University named after V.I. Lenin
Published: May 2024

Recently, there has been increasing interest in simulating of basic phenomena appearing during regeneration of bone. These phenomena include diffusion, proliferation, differentiation and apoptosis processes for the several cell types. The traditional set of cells includes four cell types (mesenchymal stem cells, fibroblasts, chondrocytes and osteoblasts). The damage space is represented as a “cell pool” where these elements can coexist. Consequently, the evolution of above-mentioned system can be described by a set of four differential equations with the corresponding boundary and initial conditions. However, the process parameters, comprising of diffusion, proliferation, differentiation and apoptosis of various cells cannot be described precisely and simplifications are necessary. As a result, various mathematical instruments are used for numerical solution of the differential equations. In the present paper, a stochastic approach based on a Markov chains is first developed for the cell-phenotype specific modelling. The Markov chain approach assumes the division of the area, which is under observation, into finite discrete intervals. The process evalutions is observed in a descrete time moments. In the context of the present work, one-dimensional model of a damaged bone area is considered as a constant cross-section cylinder. Although this model is only based on the start-up cells distributions, it provides a full description of spacetime changes of the “cell pool”. The parametric identification of the model is carried out using the experimental data borrowed from the literature.
Development of a decision support system in traumatology and orthopedics. Biomechanics as a tool for preoperative planning
Authors:   Saratov State University, Beskrovny Alexandr , Bessonov Leonid , Golyadkina Anastasia , Dol Aleksandr , Ivanov Dmitriy , Kirillova Irina , Kossovich Leonid , Sidorenko Dmitriy ,   Saratov State University
Published: May 2024

The main goal of preoperative planning for patients with pathologies of the musculoskeletal system is to obtain high-quality anatomical and functional results. The solution to this problem could be achieved through the selection of appropriate implants and technique of their installation, which ensure the stability of the structure and reposition of bone fragments, as well as by recreating the optimal biomechanics of the operated segment. All over the world, modern digital technologies are widely introduced into clinical practice. In traumatology, orthopedics and neurosurgery, preoperative planning systems that implement virtual treatment planning allow performing X-ray morphometric measurements on digital radiographs or computed tomography, as well as placing implant templates and selecting their optimal standard size. Typically, several treatment types can be planned for a particular patient, which are successful in terms of geometric preoperative planning. But not each of the planned types can be optimal in terms of assessing the stress-strain state of the studied segment of the spinal pelvic complex. Biomechanical modelling provides the possibility of virtual modelling of orthopedic operations, including the assessment of segment stability and implant "survival". Therefore, it is proposed to use biomechanical modelling as a tool for preoperative planning. In this regard, at the request and with the financial support of the Advanced Research Fund at Saratov University, for the first time, the development of a Russian medical decision support system in surgery of the spinal pelvic complex is being developed, which provides not only the stage of geometric planning of the operation, but also its biomechanical support, as well as predicting treatment results. The aim of this work was to show that biomechanical modelling makes it possible to choose the optimal type of surgical treatment of diseases and injuries of the spine-pelvic complex, and can also be successfully introduced into preoperative planning and successfully function within the framework of the medical decision support system. The paper presents the results of demonstration experiments, in which the optimal treatment types for degenerative diseases of the spine and hip joint were selected using the system. The results of the experiments were consistent with the established clinical practice and literature data, and a group of experts confirmed their clinical viability. It was shown that, together with geometric planning, biomechanical modelling forms a new method (algorithm) for preoperative planning.
Results of morphological studies of bone tissue regeneration based on conceptual approaches in surgical dentistry
Authors:   Acad. E.A. Wagner Perm State Medical University, Chetvertnykh Viktor , Vasilyuk Vladimir ,   Acad. E.A. Wagner Perm State Medical University, Eriskina Ekaterina ,   Perm National Research Polytechnic University
Published: May 2024

Oral and maxillofacial implantology has a trend towards continuous improvement. The problem being developed lies in the plane of restoration of defects in the jaw bone formed for various reasons. The range of implantation materials is constantly changing, but their structure remains unchanged – monolithic. Digital technology allows us the creation of structured implants. We have proposed designs consisting of a face-centered cubic crystal lattice and developed a technological map. Morphological studies carried out after 1, 3, 4 and 9 months after transplantation of an implant with cells of 250, 550, and 850 microns in size, showed that during these periods all cells contained lamellar bone tissue with the only difference that about a number of smaller bridges at 4 months still there are separate islands of coarse fibrous bone. This indicates a promising direction in reconstructive surgery. A retrospective study over a 15-year follow-up period after plastic surgery showed their ineffectiveness. Out of 85 plastic surgeries performed, complications were detected in 9 (37.5%) patients, which indicates the need to search for new changes in the structure of materials. Recently, in certain clinical cases, certain successes have already been achieved. However, more research is still at the theoretical development stage without the use of preclinical experimental and clinical trials.
Patient-specific models of human resected stomach after laparoscopic sleeve gastrectomy: experimental and computational results
Authors:   University of Padova, Toniolo Ilaria , Nostran Carlo , Ferrari Edoardo , Fongaro Edoardo , Fontanella Chiara , Foletto Mirto , Carniel Emanuele
Published: May 2024

The conspicuous increase in obesity rate occurring in the last decades in industrialized countries, often accompanied by high morbidity and high mortality rate, have been made obesity a global health concern. Bariatric surgery is the most effective treatment for severe obesity. However, there are still many issues related to surgical procedures not yet been overcome. The importance of experimenting with a new rational approach based on bioengineering methods could strongly improve surgical approach by avoiding drawbacks and complications. The aim of this work is the construction of patient-specific computational models of the resected stomachs after laparoscopic sleeve gastrectomy able to interpret the structural mechanical behavior of human gastric tissues. A coupled experimental-computational approach was performed. Experimental insufflation tests were performed on nine resected stomachs from laparoscopic sleeve gastrectomy. Through a reverse engineering approach, nine specific-patient computational models were developed, aiming at simulating the experimental activities. A double-layered fiber reinforced anisotropic hyperelastic material formulation was chosen. The experimental evidences provided the pressure-volume behavior of the resected stomachs. The comparison between experimental and computational results permitted to identify the set of the constitutive parameters. The stress-strain distribution described the region and the layer mainly solicited. An engineering approach allows us to characterize the mechanical behavior of the human gastric tissues. Reliable computational models will be used in understanding the biomechanics of the human stomach and will provide a clinical tool to help medical staff in optimizing bariatric procedures.
Predictors of excess fluid volume in hemodialysis patients: an observational study
Authors: Fernandes Maria Isabel da Conceição Dias , Tinôco Jéssica Dantas de Sá , Fernandes Renata Marinho , Silva Juliana Barbosa da , Almeida Anna Thays Dias , Frazão Cecília Maria Farias de Queiroz , Lopes Marcos Venícius de Oliveira , Lira Ana Luisa Brandão de Carvalho
Published: May 2024

ABSTRACT Objectives: to assess risk factors for excess fluid volume in hemodialysis patients. Methods: a retrospective case-control study was conducted. A total of 392 patients (196 cases and 196 controls) from two hemodialysis centers were included. Sociodemographic data and 23 risk factors for excess fluid volume were assessed using a data collection form. Data were analyzed using a multivariate logistic regression model. Results: the insufficient knowledge (OR=2.06), excessive fluid intake (OR=2.33), inadequate fluid removal during hemodialysis (OR=2.62) and excessive sodium intake (OR=1.91) risk factors may increase the chance of occurrence of excess fluid volume in hemodialysis patients by approximately two times. Education level (OR=0.95) and age (OR=0.97) are protective factors for excessive fluid volume. Conclusions: knowing these risk factors may help nurses with accurate and rapid diagnostic inference of the risk of excessive fluid volume.
Percepção de mães sobre o cuidado de recém-nascidos em ambiente domiciliar
Authors: Hammel Gina de Souza Castro , Simas Laura Tais Loureiro , Rodrigues Junior Luiz Fernando , Zamberlan Claudia , Lomba Lurdes , Backes Dirce Stein
Published: May 2024

RESUMO Objetivos: identificar percepções de mães sobre o cuidado de recém-nascidos em ambiente domiciliar, na perspectiva do pensamento da complexidade. Métodos: pesquisa qualitativa, de caráter exploratório e descritivo, realizada entre novembro/2022 e fevereiro/2023. Os dados foram coletados por meio de entrevistas individuais com 21 mães do sul do Brasil que cuidaram de recém-nascidos em ambiente domiciliar e analisados pela técnica de análise temática. Resultados: os quatro eixos temáticos resultantes da análise dos dados: Convivendo em meio a ordem e desordem; acolhendo às singularidades; lidando entre o certo e o incerto; rede de apoio no processo (re)organizador demonstram, que a mãe cuidadora de um recém-nascido em ambiente domiciliar vivência um processo adaptativo distinto e plural, que deve ser acolhido e compreendido pelos profissionais de saúde que atuam em âmbito familiar. Considerações Finais: o cuidado de recém-nascidos em ambiente domiciliar, na percepção de mães, requer atenção diferenciada e uma rede de apoio formal ou informal que considere as especificidades singulares de cada mulher/mãe em âmbito pessoal, familiar e social. Assim, para além da rede de apoio social é importante que se repense as abordagens de intervenção domiciliar.
Josicélia Dumêt Fernandes’ professional trajectory: contributions to psychiatric and mental health nursing
Authors: Silva Ingredy Nayara Chiacchio , Silva Gilberto Tadeu Reis da , Serra Itanna Vytoria Sousa , Almeida Deybson Borba de , Teixeira Giselle Alves da Silva , Silva Rosana Maria de Oliveira , Cordeiro Ana Lúcia Arcanjo Oliveira
Published: May 2024

ABSTRACT Objectives: to analyze nurse Josicélia Dumêt Fernandes’ life story, with emphasis on her work in the psychiatry and mental health fields. Methods: historical, qualitative research. Semi-structured interviews and documentary research were used as data collection techniques, collected from September to October 2021. For data analysis, we opted for the content analysis method and comparison with the Foucauldian philosophical framework. Results: four categories emerged: Transforming herself and mental health practices; (Re)framing professional practice; Nursing practice and power relations; and The paths and implications in the psychiatry and mental health fields. Final Considerations: the study of the biographer demonstrates a search for transformation of herself and mental health practices, with a rupture in paradigms and reframing of her practice in psychiatry and mental health.
Trajetória profissional de Josicélia Dumêt Fernandes: contribuições para a enfermagem psiquiátrica e de saúde mental
Authors: Silva Ingredy Nayara Chiacchio , Silva Gilberto Tadeu Reis da , Serra Itanna Vytoria Sousa , Almeida Deybson Borba de , Teixeira Giselle Alves da Silva , Silva Rosana Maria de Oliveira , Cordeiro Ana Lúcia Arcanjo Oliveira
Published: May 2024

RESUMO Objetivos: analisar a história de vida da enfermeira Josicélia Dumêt Fernandes, com ênfase em sua atuação na área da psiquiatria e saúde mental. Métodos: pesquisa histórica, do tipo qualitativa. Foram utilizadas como técnicas de coleta de dados a entrevista semiestruturada e a pesquisa documental, coletados de setembro a outubro de 2021. Para a análise dos dados, optou-se pelo método de análise de conteúdo e a confrontação com o referencial filosófico foucaultiano. Resultados: emergiram quatro categorias: A transformação de si e das práticas em saúde mental; A (re)significação da prática profissional; A prática de enfermagem e as relações de poder; e Os caminhos e implicações no campo da psiquiatria e da saúde mental. Considerações Finais: o estudo da biografada demonstra uma busca por transformação de si e das práticas de saúde mental, com ruptura de paradigmas e ressignificações da sua prática em psiquiatria e saúde mental.