bluuebunny/crossref_metadata_2025 huggingface dataset:
UX-MAPPER: An automated approach to analyze app store reviews with a focus on UX
Authors: Nakamura Walter T. , Oliveira Edson C. C. de , Oliveira Elaine H. T. de , Conte Tayana
Published: January 2025

The mobile app market has increased substantially in the past decades, and the myriad options in the app stores have made users less tolerant of low-quality apps. In this competitive scenario, User eXperience (UX) has emerged as an essential factor in standing out from competitors. By understanding what factors affect UX, practitioners could focus on factors that lead to positive UX while mitigating those that affect UX negatively. In this context, app store reviews emerged as a valuable resource for investigating these influential factors. However, analyzing millions of reviews can be costly and time-consuming. This article introduces UX-MAPPER, a tool designed to analyze app store reviews and assist practitioners in pinpointing factors that impact UX. We applied the Design Science Research method to develop UX-MAPPER iteratively and rooted in a robust theoretical background. We performed exploratory studies to investigate the problem, a systematic mapping study to identify UX-affecting factors, and an empirical study to ascertain practitioners’ relevance and acceptance of UX-MAPPER. In general, the participants recognized the relevance and utility of UX-MAPPER in enhancing the quality of existing apps and exploring reviews of competing apps to identify user preferences, requests, and critiques regarding functionalities and features. However, the output quality requires refinement to better convey the benefits of the results, especially for practitioners with prior experience with automated approaches. From the participants’ feedback, we defined a set of suggestions to extract more useful features, which can contribute to future studies involving user review analysis. Based on the results of this research, we present the contributions to the area of HCI and possible developments for future research.
Association between cardiac calcification, sarcopenia, bone fragility: a clinical study
Authors: Al Refaie Antonella , Baldassini Leonardo , Mondillo Caterina , Tarquini Roberto
Published: January 2025

Background: Cardiovascular disease, osteoporosis and sarcopenia are very common conditions. In recent years, interest in the association between bone, muscle and cardiovascular disease has grown. This study aimed to investigate the relationships between cardiac calcification, assessed using the Global Cardiac Calcium Score (GCCS), and bone mineral density (BMD), fragility fractures and sarcopenia. Methods: In a cohort of 106 subjects (70.4±5.8 yrs) we measured lumbar BMD (BMD-LS), femoral BMD (femoral neck: BMD-FN, total femur: BMD-FT), and body composition using dual-energy X-ray absorptiometry. We also evaluated the presence of sarcopenia. All subjects underwent transthoracic color Doppler echocardiography to assess, by means of the GCCS, the presence of valvular calcification. Results: After dividing the population, on the basis of their T-scores, into osteoporosis, osteopenia and normality, the degree of valve calcification as assessed using the GCCS was found to be significantly higher in the patients with osteoporosis (p<0.001). An inverse correlation emerged between the BMD and GCCS values which reached statistical significance at the level of the lumbar spine and femoral sub-regions in the female population (p<0.01). After dividing the population by the presence of fragility fractures, we observed that GCCS values were significantly higher in subjects with fractures versus non-fractured ones (p<0.05). Multiple regression models showed that BMD-LS and BMD-FT were independently associated with cardiac calcification. GCCS values were significantly associated with BMI and appendicular skeletal muscle mass in women (p<0.01 and p<0.05, respectively) and with handgrip strength in men (p<0.05). Conclusion: Our data confirm the presence of a relationship between valvular calcification and decreased BMD values. This is also the first study which relates sarcopenia with valvular calcification. KEY WORDS: Osteoporosis, cardiac calcification, sarcopenia, GCCS, bone mineral density, cardiovascular risk, echocardiography.
„Gute Kinder- und Jugendmedienangebote ins Zentrum stellen“
Authors: Barg Werner
Published: January 2025

Das Deutsche Kinder- und Jugendfilmzentrum (KJF) wurde 1977 gegründet und agiert in der Rechtsträgerschaft der Akademie der Kulturellen Bildung des Bundes und des Landes NRW in Remscheid. Die Organisation und Durchfüh- rung von Bundeswettbewerben für Kinder und Jugendliche in den Formaten Foto, Film und Multimedia ist eines der zentralen Aufgabenfelder des Zen- trums; Kulturelle Medienbildung in der Form einer umfassenden Empfeh- lungs- und Bildungsarbeit eine zweite wichtige Säule der Arbeit. Der Beitrag stellt die Entwicklung dieser Arbeitsbereiche seit der KJF-Gründung bis heu- te vor dem Hintergrund der sich seither stark gewandelten Medienwelt von Kindern und Jugendlichen dar. Die Ausführungen beziehen auch Ergebnisse von Gesprächen mit ein, die der Autor mit dem früheren KJF-Leiter Horst Schäfer, seiner Nachfolgerin Dr. Eva Bürgermeister und dem derzeitigen Lei- ter Thomas Hartmann geführt hat.
Hatespeech in sozialen Netzwerken, Fakenews und Deepfakes
Authors: von Gottberg Joachim
Published: January 2025

Elon Musk, wohl der reichste Mann der Welt, Industrieller und Medienmogul, sitzt demnächst als wichtiger Berater in Donald Trumps Kabinett: Eine noch nie gekannte Symbiose von Politik, Macht und Kapital. Die Tesla-Aktie hat sich nach dem Wahlsieg von Trump noch mal um 15 Prozent im Wert gestei- gert. Was bedeutet das für die Demokratie, den Pluralismus, die Meinungs- freiheit und insgesamt den Rechtsstaat? Was bedeutet das für Deutschland und was sollten wir unternehmen, um vor allem die jungen Wähler für diese Gefahr zu sensibilisieren?
Das neue Recht der Künstlichen Intelligenz
Authors: Wendt Janine , Wendt Domenik H.
Published: January 2025

Mit dem AI Act ist erstmals ein Rechtsrahmen für die Entwicklung, das Inverkehrbringen und die Nutzung von KI-Systemen geschaffen worden. Die EU-Verordnung betrifft damit unmittelbar alle Anbieter und Betreiber von KI-Systemen.

Das Handbuch
bietet einen schnellen Zugang zur komplexen Regelungsstruktur der EU-Verordnung und erläutert Schritt für Schritt die wesentlichen Vorgaben des AI Acts.

Ihr Vorteil
Das Handbuch erläutert Schritt für Schritt die wesentlichen Vorgaben des AI Acts. Betroffene Unternehmen können diese rechtzeitig erkennen und rechtssicher anwenden. Zudem werden haftungsrechtliche Fragestellungen unter Berücksichtigung des Entwurfs der neuen AI Liability Directive behandelt.
Enhancing Nutritional and Sensory Quality of Plant-Based Foods through Arbuscular Mycorrhizal Fungi
Authors: Alberto Gío-Trujillo José , Juan Alvarado-López Carlos
Published: January 2025

Arbuscular mycorrhizal fungi (AMF) play an important role in the nutritional dynamics of plants. Influencing the extraction, translocation and distribution of minerals from the soil to the plant. This has a positive effect on the mineral and nutritional content of agricultural crops. Therefore, HMA is considered a sustainable alternative, reducing the use of fertilizers by up to 50–70%. It should also be taken into account as a microbial soil resource that can contribute to self-sufficiency, food security and sovereignty in marginalized soils and areas vulnerable to population malnutrition. This chapter mentions relevant studies in relation to mycorrhizal interaction with the quality of plant foods. Recent findings have reported an increase in zinc and iron content in basic grains. Some alternative crops such as fruit, vegetables and edible foliage, have increased their phytochemical content (organic acids, phenols, carotenoids, etc.) and post-harvest properties such as texture, colorimetry and sugar content. This directly influences the taste, smell and palatability of food. In conclusion, AMF is considered a strategy to optimize and transform agro-food systems, oriented toward nutritional and sensory enrichment of plant tissues that can be used for human consumption.
Biocompounds of Commercial Interest from Freshwater and Marine Phytoplankton
Authors: Gallego Irene
Published: January 2025

Microalgae are photosynthetic microorganisms that produce a wide range of biocompounds, such as proteins, omega-3 fatty acids or pigments like astaxanthin; with various applications in the pharmaceutical, cosmetic, bioenergy and food sectors. This chapter provides an overview of the compounds and molecules synthesized by microalgae, ranging from polysaccharides to vitamins, minerals and other secondary metabolites. Additionally, the chapter reviews the key biological aspects that influence the production of such biocompounds, including strain selection, strain improvement and cultivation conditions, as well as the biotechnological factors necessary to optimize the production and processing of these compounds, such as cultivation system, extraction and purification. Lastly, the chapter presents the main applications of commercially relevant microalgae-derived compounds, emphasizing the most notable microalgae-based products currently being developed in the global market.
NGS and Immunogenetics: Sequencing the HLA Genes
Authors: Mirela Caragea Andreea , Camil Bohiltea Laurentiu , Constantinescu Alexandra , Constantinescu Ileana , Ursu Radu-Ioan
Published: January 2025

Next-generation sequencing (NGS) has completely revolutionized the analysis of HLA genes, offering superior resolution and the possibility of identifying previously unknown or rare alleles. NGS technology allows for the complete sequencing of the the HLA locus, the analysis of coding and non-coding regions, and a detailed characterization of haplotypes, with essential benefits in areas such as organ transplantation and in studies of autoimmune diseases. The chapter explores the applications of NGS in personalized medicine, including the identification of neoantigens for oncology immunotherapies and the development of vaccines adapted to the genetic diversity of the population. Bioinformatic and ethical challenges are also discussed. By reducing the limitations of traditional methods and opening up new horizons for research and clinical applications, NGS is redefining the standards in HLA typing and is making a significant contribution to the progress of precision medicine.
Sacred Signs or Empty Words: A Naturalistic and Semiotic Comparison of AI vs Human Generated Art
Authors: Hellberg Dustin
Published: January 2025

This article analyzes the differences between human literary artistic works and those generated by AI programs like Chat GPT. While interesting as a technology, could AI ever be said to generate a work of art or literature? This paper differentiates AI generated writing from human generated writing by appeal to humans’ evolved sociability, especially the human capacity for joint intentionality. The blurry nature of authorship and text becomes more clear by examination through Charles Peirce’s semiotic system, especially his notions of the rheme and dicisign. It furthers this point through examining the Umwelt of institutional facts and sacredness in esthetic texts.
Examination of the Entrepreneurship Levels of Translation and Interpreting Students in terms of Personal and Social Variables
Authors: Zorlu Beyza Nur , Köksal Onur
Published: January 2025

Entrepreneurship, which means taking action to do something, is becoming more and more important in the field of Social Sciences every day. There is a need for individuals who are willing to take opportunities, responsible for what they do, able to take risks, and do not hesitate to add new perspectives to the field. This study examines the entrepreneurship levels of the students studying in the department of Translation and Interpreting at Selçuk University in terms of personal and social variables. The personal and social variables taken into consideration in this study give an insight about what a successful translator-to -be and/or an interpreter-to -be should be like. The research is conducted by taking into consideration the junior and senior students of the department. In order to examine the entrepreneurship levels of the students, a 51-item measurement tool named "Entrepreneurship Scale for Students of Foreign Languages” is used, and some additional information about the students’ personal and social characteristics are collected in the research. The study finds that there is no significant difference in the entrepreneurship levels of the students studying in the department of translation and interpreting at Selçuk University when other variables are taken into account, except for the gender variable. When the gender variable is analyzed, it is noteworthy that a significant difference in entrepreneurship levels has been detected between male and female students: female students are more entrepreneurial than male students. The reason why female students are more entrepreneurial than male students may be related to the fact that women tend to be more intuitive and self-regulated, which are still found to be some of the most important factors for university students’ entrepreneurial activities.
DENTAL BLEACHING POSSIBILITIES IN THE DENTAL OFFICE
Authors:   Department of Endodontics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Popescu Alexandru-Dan , Mercuţ Veronica ,   Department of Dental Prosthetics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Ţuculină Mihaela Jana , Bugălă Adelina Smaranda , Rîcă Ana-Maria , Diaconu Oana Andreea , Gheorghe Anca , Bănică Carina ,   Department of Endodontics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Bătăiosu Marilena ,   Department of Pedodontics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Gheorghiţă Lelia Mihaela
Published: January 2025

(1) Background: Tooth bleaching is a minimally invasive, precise, practical, conservative, and accessible clinical procedure for patients, involving a low degree of difficulty in performance, resulting in improved tooth color. Different tooth bleaching techniques exist, and their use depends on the type and concentration of the bleaching agent as well as the patient’s clinical situation. The study aims to evaluate the aesthetic and clinical efficacy of tooth-bleaching products, analyze their safety, and determine the duration of the bleaching effect. (2) Methods: The study was conducted in the Odontotherapy Clinic of the Faculty of Dental Medicine, Craiova, between April 2023 and June 2024. The study analyzed the efficiency and safety of the bleaching products and the duration of the aesthetic effects obtained. After the end of the bleaching treatment, the clinical results were appreciated. The most relevant cases were presented. (3) Results: The study includes 15 clinical cases with patients who benefited from tooth bleaching treatment. (4) Conclusions: Teeth bleaching with peroxides is an effective method of correcting dental dyschromia, with notable results when performed under the supervision of a specialist under controlled conditions. The area most affected by dental dyschromia is the anterior one, which affects aesthetics and determines patients to want a tooth bleaching treatment.
Survei Tingkat Skill Related Fitness Pada Siswa-Siswi Sekolah Dasar Negeri Gugus 6-10 Fase C Di Kecamatan Sukun Kota Malang
Authors: Romdlon Auli Fahmi Nadhifatur , Wiguno Lokananta Teguh Hari
Published: January 2025

The purpose of this study was to determine the level of physical fitness of students in public elementary schools in cluster 6-10 phase c in Sukun District, Malang City. This research is a survey research, using quantitative descriptive methods, the instrument used in collecting data is the Indonesian Student Fitness Test (TKSI). The study sample involved 95 public primary school students of cluster 6-10 phase c in Sukun District, Malang City. The results of the study showed that the 95 students of public primary schools of cluster 6-10 phase c in Sukun District, Malang City as a whole showed that the 40 Meter Run Test was dominated by the “Very Poor” category with 58 (fifty-eight) frequencies. The 8x10 Meter Shuttle Run Test is dominated by the “Excellent” category with 37 (thirty-seven) frequencies. Child Ball Test is dominated by the “Excellent” category with 44 (forty-four) frequencies. Dynamic Balance Test was dominated by the “Good” category with 53 (fifty-three) frequencies. Vertical Jump Test was dominated by the “Moderate” category with 42 (forty-two) frequencies. Hand Touch Reaction Test is dominated by the “Poor” category with 34 (thirty-four) frequencies. With this, the researcher hopes that public elementary schools in cluster 6-10 in Sukun District, Malang City will pay more attention and try to increase the overall level of physical fitness of students.
Peran Manajemen Pendidikan dalam Mewujudkan Sekolah Berkualitas
Authors: Fathurrahman Suryadi  , Muhammad Habib Pasaribu  , Aqbil Daffa Siahaan  , Ahmad Sabri  , Yusran Lubis
Published: January 2025

Optimizing education management in schools is a strategic step to achieve superior education quality, where various aspects such as human resource development, utilization of facilities and infrastructure, and education supervision play an important role in creating a conducive learning environment and responsive to student needs. The purpose of this study is to examine more deeply the role of education management in realizing quality schools. The research method to be used in this study is a literature study approach, in which data and information will be collected from various academic sources, such as books, journals and relevant articles on education management and quality schools. The results of this study show that effective education management plays a key role in creating quality schools through key components such as human resources, facilities and infrastructure, finance and education supervision. Each of these components works synergistically to support optimal learning processes, although they often face challenges such as limited resources, resistance to change and lack of stakeholder support. Through collaborative strategies from various parties, including the government, community and parents, schools can overcome these obstacles. Optimizing education management complemented by educational supervision helps improve the professional quality of teachers, curriculum and school management, and builds a culture of continuous evaluation. This synergy results in schools that are qualified, adaptive and able to respond to the demands of today's education.
Problematika Pembelajaran Bahasa Indonesia Di Sekolah: Faktor Guru, Siswa, Serta Media Pembelajaran
Authors: Hendarti Hendarti
Published: January 2025

The issues in school learning are diverse, with several factors contributing to these challenges, including teachers, students, and the learning media used by teachers. Every teacher must continuously innovate in creating learning media that meet the needs of students. This can help minimize the challenges in teaching the Indonesian language in the classroom. Meanwhile, student learning factors and media also impact the Indonesian language learning process. Students often face difficulties in understanding the language or information being taught, which lowers their interest in learning. Additionally, the media used are often less effective and lack interactivity, failing to meet the current needs of students. This includes limited use of technology or a wide range of digital learning resources, indicating that the combination of student limitations and poor adaptation represents a significant challenge for effective and engaging Indonesian language learning.
Analisis Gaya Bahasa Dalam Novel " Senja, Hujan, Dan Cerita Yang Telah Usai " Karya Boy Candra
Authors: Welly Karmelia  , Emi Mutiara
Published: January 2025

Figurative speech is inseparable with literary works, particularly to express intrinsic elements in the works. Practically, authors often insert figurative speech to narrate a story. This study is aimed at analyzing figurative speeches in novel Senja, Hujan, dan Cerita Yang Telah Usai, written by Boy Candra. The researcher employed literary study to finish the study which initiated by (i) reading the research object, (ii) collecting the data by marking, identifying, and transcribing. The data were analyzed by using interactive model of analysis. The result showed that the author used 6 types of f igurative speeches to describe both the setting and character, as follows; (1) allegory, (2) (2) alusio, (3) antitesis, (4) asindenton, (5)Klimaks, (6)interupsi. The result of the study strongly suggested that the use of figurative speech is clearly necessary to improve the quality of literary works.
Analisis Kesalahan Penggunaan Huruf Kapital pada Tiga Surat dari Pemenang Lomba Menulis Surat untuk Mendikbud
Authors: Firda Puspita Cahya  , Aida Sofie Rahman  , Ezzah Tanisha  , M. Bahrul Mafaza  , Nazwa Azria Khaifa
Published: January 2025

Bahasa Indonesia as an official communication tool had grammatical guidelines such as Ejaan Bahasa Indonesia yang Disempurnakan (EYD) V, which was used to regulate the use of letters, punctuation, and word writing. One important aspect of this grammar was the correct use of capital letters. Unfortunately, there were still many errors in applying this rule, both in scientific and non-scientific writing. This study aimed to analyze the capitalization errors in the three winning letters of the Writing a Letter to the Minister of Education and Culture competition published on the Instagram account @kemdikbud.ri. This research used a qualitative method to examine the errors in capitalization in more depth. The results showed that most errors occurred in using capital letters at the beginning of sentences and proper names, and there were also inappropriate capital letters in the middle of sentences. Further education on capitalization was still needed, especially to improve good and correct writing skills according to Indonesian language guidelines.
Keutamaan Ilmu dalam Al-Qur’an dan Hadits : Perspektif Kitab Mahfudzot Fadhoilun Nabi wa Shahabat dalam Membangun Karakter Mahasiswa Universitas Islam Zainul Hasan Genggong Probolinggo
Authors: Sri Idhom Utami  , Ainur Rofiq Sofa
Published: January 2025

This research investigates the significance of knowledge as presented in the Qur'an and Hadith, focusing on the Mahfudzot Fadhoilun Nabi wa Shahabat as a framework for understanding its role in shaping the character of students at Universitas Islam Zainul Hasan Genggong Probolinggo. The study examines how the Qur'anic and Hadith perspectives on knowledge emphasize moral, intellectual, and spiritual development and how these teachings can be applied to enhance the character of university students. By analyzing the implementation of these teachings within the academic and social environments, this research explores how knowledge, within the Islamic context, contributes to the development of ethical and responsible individuals. The findings are expected to offer valuable insights into the integration of Islamic values in higher education and their impact on the formation of student character.
Pengaruh Model Pembelajaran Two Stay Two Stray (TSTS) Terhadap Keterampilan Menyimak Siswa Kelas V Sekolah Dasar
Authors: Annisa Ulhasanah  , Eddy Noviana  , Intan Kartika Sari
Published: January 2025

This study aims to determine the effect of using the Two Stay Two Stray (TSTS) learning model on the listening skills of fifth-grade students. The research was conducted in classes VB and VC at UPT SDN 015 Sumber Sari, involving a total of 62 students, during the odd semester of the 2024/2025 academic year, specifically in July 2024. The study utilized a Non-Equivalent Control Group Design, involving two classes: VC as the experimental class with 32 students and VB as the control class with 30 students. In the experimental class, learning was conducted using the Two Stay Two Stray (TSTS) model, while in the control class, conventional teaching methods were applied. Students' listening skills were assessed through pretests and posttests in audio format, each consisting of 20 questions. The data collected were analyzed using normality tests, homogeneity tests, and hypothesis testing through the SPSS 24 application. The results showed that hypothesis testing using the t-test produced a significance value of 0.000 < 0.05, indicating that Ha was accepted and Ho was rejected. These findings suggest a significant effect of applying the Two Stay Two Stray (TSTS) learning model on students' listening skills. This improvement was evident from the average posttest scores, with the experimental class achieving an average of 83.48, higher than the control class's average of 71.74. Thus, this study confirms that the use of the Two Stay Two Stray (TSTS) model is effective in enhancing the listening skills of fifth-grade elementary school students.
Pengaruh Penggunaan Bahasa Gaul Dalam Interaksi Mahasiswa : Studi Kualitatif Tentang Penggunaan Bahasa Gaul Dikalangan Mahasiswa IKM UINSU
Authors: Usiono Usiono  , Nesa Ariska  , Aisha Nurul Azkia  , Nur Azizah Chairuna Balqis Tanjung
Published: January 2025

This research aims to explore more deeply the phenomenon of slang use among UINSU Public Health students and its impact on social dynamics and the development of their identity. Through a qualitative approach involving in-depth interviews and participant observation, this research seeks to understand how slang plays a role in forming social bonds, creating a sense of belonging to a group, and influencing the way students interact with each other. Preliminary findings show that slang not only functions as a communication tool, but also as a symbol of identity and a means of expressing oneself. However, on the other hand, the use of slang that is too intense can blur the boundaries between formality and informality, thus potentially hampering the learning process and effective academic communication. Therefore, this research highlights the importance of balancing the use of slang with good and correct language rules, so that students can communicate effectively in various contexts without sacrificing their group identity.
PENGUJIAN WAKTU ADAPTASI, PALATABILITAS, PERSENTASE DISINTEGRASI DAN KONSUMSI RANSUM HIPROMIN BLOK BERBAHAN BAKU WATAR HAMMU (SORGHUM) PADA TERNAK SAPI SUMBA ONGOLE
Authors: Sudarma I Made Adi , Nganji Marten U. , Babang Ruth Noti , Nggeding Srilus L. , Windi Rano K.K.
Published: January 2025

Penelitian ini bertujuan untuk mengembangkan ransum Hipromin blok khusus ternak sapi dan mengevaluasi respon ternak sapi Sumba Ongole yang mendapatkan ransum blok tersebut. Ransum blok memiliki berat 1 kg bahan kering dengan menggunakan bahan baku lokal seperti biomassa watar hammu varietas kiku mbimbi, hay lamtoro, hay odot, tepung kanji dan mineral. Penelitian ini menggunakan tiga perlakuan komposisi watar hammu 20%(P1), 30%(P2), dan 40%(P3) pada ransum blok yang diberikan pada 6 ekor ternak sapi Sumba Ongole dengan sistem kafetaria selama 5 hari. Hasil penelitian menunjukkan bahwa semua level biomassa watar hammu memiliki palatabilitas yang baik sehingga tidak membutuhkan waktu yang lama untuk ternak mengkonsumsi ransum blok yang diberikan. Hasil analisis statistic memperlihatkan bahwa perlakuan P3 (biomassa watar hammu 40%) memberikan hasil terbaik pada variabel waktu untuk mulai mengkonsumsi (2,5 menit) dan konsumsi total ransum (840 gram/9 jam). Namun, tidak ada perbedaan yang nyata pada perlakuan toral waktu konsumsi dan persentase disintegrasi. Dapat disimpulkan bahwa penggunaan bahan baku biomassa watar hammu hingga 40% dapat diaplikasikan pada ransum hipromin block dan disukai oleh ternak sapi Sumba Ongole.
BABESIOSIS IN HUMANS
Authors: Traykova Zornitsa
Published: January 2025

Babesiosis is a tick-borne parasitic disease caused by the intraerythrocytic protozoan Babesia spp. and transmitted primarily by Ixodes ticks. The geographical distribution of the parasites coincides with the regions where their tick vectors are prevalent. More than 50 cases of human babesiosis have been reported in Europe, mainly associated with Babesia divergens, which causes acute disease in cattle and is transmitted by Ixodes ricinus. In contrast, the incidence of the disease in the USA is approximately 2000 cases per year, with the main causative agent being Babesia microti and the tick vector being Ixodes scapularis. Although babesiosis is primarily an animal disease, humans can also become acutely ill, particularly splenectomized and immunocompromised individuals. Clinical manifestations range from asymptomatic to severe disease with symptoms including fever, chills, hemoglobinuria and anemia. There is a risk of potentially fatal complications such as acute respiratory, renal or multi-organ failure, particularly in vulnerable populations. Diagnosis is primarily based on light microscopy and PCR testing, while serological methods are more appropriate for epidemiological studies. Treatment regimens typically include a 7-10 day course of either atovaquone plus azithromycin or clindamycin plus quinine. Human cases are associated with outdoor activities or living in rural areas during the warm months when tick activity is at its peak. Because of the increasing incidence in endemic regions and the potentially serious clinical consequences, babesiosis should be considered in the differential diagnosis of febrile illnesses of unknown origin.
EVALUATION OF THE APPLICABILITY OF THE O.K.N.V.I. RESIST-5 AND THE KPC&MBL&0XA-48 DISK TESTS IN A ROUTINE MICROBIOLOGY LABORATORY
Authors: Sabtcheva Stefana , Georgieva Sylvia
Published: January 2025

Background: The global spread of carbapenemase-producing Enterobacterales (CPE) and the increasing emergence of clinical Enterobacterales harboring multiple carbapenemases of different molecular classes have prioritized the use of rapid molecular detection methods in routine microbiology laboratories. The aim of this study was to evaluate the applicability of the immunochromatographic O. K.N.V.I. RESIST-5 and the KPC&MBL&0XA-48 disc tests in a clinical microbiology laboratory.
Material and methods: The tests were performed with 50 CPE belonging to 8 species and producing 7 molecularly characterized carbapenemases. Six of these isolates carried two different carbapenemases. To assess the specificity of the assays, 18 non-carbapenemase-producing but carbapenem-resistant Enterobacterales (non-CP CRE) were also included. Both tests were performed from a common overnight culture on Mueller-Hinton agar with inoculum harvested around an ertapenem disk.
Results: The O.K.N.V.I. RESIST-5 correctly detected all 56 carbapenemases, including KPC-2 in Klebsiella pneumoniae; OX-48 in Serratia marcescens, Citrobacter freundii, Enterobacter hormaechei and K. pneumoniae; NDM-1 in Escherichia coli, Morganella morganii, E. hormaechei, C. freundii, S. marcescens and K. pneumoniae; VIM-1 in Proteus mirabilis; VIM-4 in C. freundii and S. marcescens; VIM-86 with and without NDM-1 in Providencia stuartii, and NDM-5 with and without OXA-232 in K. pneumoniae. The KPC&MBL&0XA-48 disc tests correctly confirmed KPC, OX-48-like and most MBL except VIM in P. mirabilis. Furthermore, the combination disc tests failed to detect OXA-48-like in pairs with MBL in K. pneumoniae.
Conclusions:The O.K.N.V.I. RESIST-5 multiplex lateral assay is an excellent test for rapid diagnostic of CPE in routine microbiology laboratories. It is easy to handle and provides results with 100% sensitivity and specificity when an inoculum around ertapenem disc from routine antibiogram was used.
CASE REPORT ON TWO CONSECUTIVE PATIENTS WITH NEUROINVASIVE WEST NILE VIRUS INFECTION IN AN INTENSIVE CARE UNIT
Authors: Stoyanova Silviya , Mihaylova-Garnizova Raynichka , Naseva Emilia , Dakova Severina , Christova Iva , Ramshev Konstantin
Published: January 2025

We present the clinical course, and treatment of two consecutive cases of neuroinvasive West Nile virus (WNV) infection in the Clinic of Intensive Care, an Intensive Care Unit (ICU) at the Military Medical Academy - Sofia. Clinical and epidemiological data, microbiological, laboratory, molecular methods, and imaging techniques were used. Both patients resided in Sofia, Bulgaria, and had not travelled in recent months. The first case was a 60-year-old man who have had mental status changes, fever, and progression of existing Parkinson's disease. Antibodies to WNV were present in cerebrospinal fluid (CSF). His condition worsened with the development of sepsis and respiratory failure and he ended up lethally. The second case was a 72-year-old man who had fever and lower dyspeptic syndrome for one week, mental status changes, with adynamia to inability to walk independently, and head, hand and tongue tremors. CSF analysis showed mild pleocytosis with proteinorachy. Antibodies to WNV were present in serum, and PCR for WNV in urine was positive. The patient was admitted to ICU due to worsened mental and neurological status, coma and development of acute respiratory failure, necessitating intubation and assisted pulmonary ventilation. The patient ended lethally 13 days later. Neuroinvasive WNV infection can cause substantial morbidity, particularly among older adults, and high mortality, in the presence of comorbidities. Physicians should include West Nile virus infection in the differential diagnosis of aseptic meningitis and encephalitis, should perform appropriate laboratory tests, and report immediately the cases to the public health authorities.
Socio-Environmental Accessibility in Inclusive Schools in Buea Municipality by Students with Special Needs
Authors: Faizefu Ambei Ruhama
Published: January 2025

Aim: The study sought to investigate socio-environmental accessibility in inclusive schools in Buea Municipality, Cameroon, emphasizing students with special needs. To accomplish this, the percentage of inclusive schools that fulfill accessibility requirements for students with physical, sensory, and cognitive disabilities, the accessibility and use of assistive technology and learning resources tailored to diverse students' needs, and the degree of preparation and assurance of educators in applying inclusive teaching methods were investigated.
Methods: Four major theories were employed to support the research. This study was conducted in four distinct inclusive schools in the Buea Municipality. A random sampling procedure was utilized to recruit a sample of 80 students with various types of disabilities, 20 from each school. A mixed-methods research design was used, combining quantitative and qualitative data. Data was collected through a questionnaire and interview guides and expressed using percentages and frequencies.
Results: The study found that most respondents recognized that inclusive schools in the Buea Municipality of Cameroon meet accessibility requirements for students with disabilities. Many interviewees stated that inclusive schools in Buea Municipality have suitable assistive technology and learning tools. Also, respondents agreed that inclusive schools in Buea Municipality lacked suitable assistive technology and learning tools. Respondents agreed that educators' preparation and assurance using inclusive teaching approaches were appropriate. Other respondents believed that educators' preparation and confidence in utilizing inclusive teaching approaches were inadequate.
Conclusion: Well-structured professional development activities greatly improve instructors’ readiness to apply inclusive practices, improving student engagement and learning results.
Recommendation: Immediate legislative changes and investments in school infrastructure is needed to ensure that all students can thrive in an inclusive learning environment.
Keywords: Accessibility, socio-environmental accessibility, assistive devices, inclusive schools, special needs
Grain Trade: A Literature Review and Research Outlook
Authors: Xu Ting
Published: January 2025

Grain trade plays a critical role in global grain security and the balance of grain supply and demand across countries. As globalization progresses, the complexity and diversity of grain trade have become increasingly prominent. Its significance extends beyond the economic sphere, directly impacting social stability and international relations. The dynamic development of grain trade is influenced by a variety of factors, including climate change, international economic policies, technological advancements, and geopolitics. At the same time, the complexity of global grain supply chains, the uncertainty of international trade policies, and the frequent occurrence of extreme climate events pose significant challenges to the smooth operation of grain trade. In recent years, there has been growing attention in the international community on how to achieve the sustainable development of grain trade by optimizing policies, strengthening international cooperation, and promoting technological innovation. This study systematically reviews the existing literature on grain trade, providing a comprehensive summary of the research landscape, covering factors influencing grain trade, development trends, supply chain management, and risk management. The goal is to provide a systematic analysis and insights for both academics and policymakers, as well as directions and references for future research. Additionally, the study explores how grain trade has maintained resilience amid global crises such as the COVID-19 pandemic and climate change, and offers strategic recommendations for achieving global grain security. This research aims to further promote the sustainable development of grain trade systems and provide strong support for global grain security and socioeconomic stability.
New Quality Productivity, Institutional Environment and Sustained Firm Innovation
Authors: Sun Han
Published: January 2025

This paper investigates the impact of new quality productivity on corporate innovation, and empirically analyzes it using A-share data from 2012-2022. New quality productivity, which includes emerging industries, future industries and digital transformation of traditional industries, has a significant positive effect on corporate innovation. The study shows that new quality productivity promotes innovation by enhancing innovation incentives and improving ESG performance. Improvements in the institutional environment can enhance its role in promoting innovation. It is recommended to enhance new quality productivity, stimulate innovation in SMEs, focus on ESG performance and develop differentiated strategies to support sustained innovation in corporate technology.
La política exterior de Andrés Manuel López Obrador: el rol del presidente y la delegación a las burocracias
Authors: Franzoni Marcela , Sposito Italo Beltrão
Published: January 2025

La política exterior mexicana (PEM) se ha mantenido constante desde el siglo XX, con énfasis en la relación con Estados Unidos y una orientación económica liberal, influenciada por presidentes de derecha y factores estructurales. No obstante, el final del largo gobierno del Partido Revolucionario Institucional ha avivado el debate sobre posibles cambios. Este artículo se propone analizar la PEM de 2019 a 2023, durante la presidencia de Andrés Manuel López Obrador (AMLO), un periodo marcado por expectativas de transformación. Utilizamos la metodología cualitativa, específicamente el estudio de caso, recurriendo a fuentes primarias y secundarias, evaluadas a partir del análisis de contenido interpretativo, y una moldura teórica embazada en supuestos básicos de la subárea de análisis de política exterior para evaluar los efectos de los condicionantes estructurales y la influencia de actores clave sobre la PEM. Se pone especial énfasis en la gestión de AMLO, examinando su potencial impacto, la delegación de responsabilidades a burocracias especializadas y las modificaciones en la política exterior. Argumentamos que, por un lado, AMLO adoptó un perfil predominantemente pragmático en temas estructurales, como el de las relaciones con EE. UU., en el cual él optó por aprovecharse de la competencia de las burocracias y mantener la continuidad. Por otro lado, en un eje de mayor autonomía, como el de las relaciones con América Latina y el Caribe, adoptó posiciones más ideológicas, aunque instrumentalizándolas para complacer su base doméstica. Pese a las expectativas, AMLO todavía no ha generado cambios revolucionarios en política exterior, con los factores estructurales siendo determinantes en tal resultado.
A formação continuada de professores como objeto de pesquisa no Brasil e em Portugal: estado do conhecimento
Authors: Valle Paulo Roberto Dalla , Ferreira Jacques de Lima
Published: January 2025

Este artigo tem como objetivo mapear e analisar as teses publicadas no Brasil e em Portugal sobre a Formação Continuada de Professores diante das suas interfaces e dos seus aspectos teóricos e metodológicos. Para tal propósito, realizou-se uma pesquisa do tipo Estado do Conhecimento que considerou as teses publicadas no Banco de Teses e Dissertações da CAPES (Brasil) e no Repositório Científico de Acesso Aberto de Portugal (Portugal) no período de 2018 a 2023. A análise dos resumos demonstrou fragilidades na construção e apresentação, dificultando a compreensão detalhada das metodologias de pesquisa. Identificaram-se também convergências e similitudes entre as teses produzidas nos dois países acerca dos aspectos teórico-metodológicos, a capilaridade do tema em diferentes programas de pós-graduação e a confluência com subtemas/temáticas contemporâneas. Infere-se, a partir do conjunto dos dados obtidos, a existência das ressonâncias entre as teses produzidas e analisadas, em que a formação continuada de professores enquanto objeto de investigação sob diferentes perspectivas: i) a partir de programas/projetos propostos e desenvolvidos pelos pesquisadores; ii) a partir da investigação de programas/projetos de formação dos quais os sujeitos da pesquisa já tenham participado, mas que não foram propostos e desenvolvidos pelos pesquisadores; iii) a partir de pesquisas que a consideram como um campo de conhecimento, incumbindo-se mais de discussões teóricas e críticas; e iv) nas situações em que as pesquisas são realizadas expressivamente com abordagem qualitativa, descritiva e exploratória, utilizando-se da análise de conteúdo como método para análise de dados.
Masculinidades pretas e afrodiaspóricas no Brasil: castigo e tortura contra os negros
Authors: Cassiano Thiago Francysco Rodrigues , Rocha José Damião Trindade
Published: January 2025

Este estudo examina a continuidade das práticas de tortura e punição direcionadas às masculinidades pretas e afrodiaspóricas no Brasil, com aspectos do período colonial a modernidade. Com objetivo de evidenciar como essas práticas permanecem como mecanismos de controle social e expressão de poder racial, o estudo formula sua pesquisa a partir do conceito de racismo recreativo em Moreira (2019). Metodologicamente, adota-se a revisão bibliográfica interdisciplinar, fundamentada em dados históricos e jornalísticos, inspirada pela pesquisa implicada Macedo (2012). O referencial teórico aborda contribuições de Moura (1988,1992) e Lara (1988), que tratam de resistências das comunidades pretas e as estruturas raciais de opressão. Os resultados revelam que, embora as práticas físicas de tortura tenham mudado de forma, a violência racial persiste de maneira sádica e institucionalizada, reforçando a supremacia branca. Nesse sentido propomos um enfrentamento crítico e coletivo ao racismo estrutural e suas manifestações, a partir de Fanon (2008); Bento (2022) e Allport (1954), visando à equidade racial.
Ritmos da resistência - cantoras negras brasileiras sob o enfoque da interseccionalidade
Authors: Cambui Eni Gonçalves da Silva , Cordeiro Ana Luisa Alves
Published: January 2025

Este artigo tem como panorama social a condição das mulheres negras brasileiras, suas resistências às opressões de raça, gênero e classe enquanto práxis educativa interseccional na construção da cultura das mulheres negras. O objetivo é refletir sobre como algumas cantoras negras brasileiras utilizam educativamente da música como um instrumento de resistência ao racismo, patriarcado e capitalismo, construindo uma cultura das mulheres negras de resistência às opressões, mas também afirmação da identidade negra. O aporte teórico utiliza-se dos campos do Feminismo Negro em interface com a Educação das Relações Étnico-raciais. Metodologicamente, é de abordagem qualitativa e se caracteriza como uma pesquisa bibliográfica. Em nossa análise, destacamos exemplos de cantoras negras brasileiras que demonstram em suas obras uma forte conexão com temas de resistência de mulheres negras. Concluímos que suas práticas artísticas transcendem o entretenimento, exercendo um impacto significativo na práxis educativa interseccional, na conscientização coletiva sobre questões de raça, gênero e classe, voltadas para emancipação humana.
Identidade algorítmica: imagens da negritude e viés racista
Authors: Silva Valmir Luis Saldanha da
Published: January 2025

As inteligências artificiais generativas e seus algoritmos são responsáveis por cada vez mais decisões em nossa sociedade. No entanto, por mais que sejam tidos como ferramentas imparciais, os dados de algoritmos com viés racial que prejudicam pessoas negras em diversas áreas da vida não param de crescer. A este fenômeno demos o nome de Identidade Algorítmica. Com base nisso, e com o entendimento de que a oposição real X fictício não se sustenta, tendo de ser trocada pela tríade real-fictício-imaginário, neste estudo demonstramos os problemas relativos aos vieses cognitivos que norteiam a construção de identidades que saem do mundo off-line e adentram o mundo on-line, principalmente pela subalternização das imagens de pessoas negras. Além disso, indicamos como as identidades algorítmicas estereotipadas colocam-se como uma barreira à efetiva inclusão sociodigital. Como possibilidade de enfrentamento, propomos a criação de um material didático voltado para o letramento sobre argumentação, elementos implícitos e vieses algorítmicos, com foco nos anos finais do Ensino Médio e nos anos iniciais de cursos universitários.
Razão, política e revelação: Strauss e o esclarecimento filosófico medieval
Authors: Lobo Iann Endo
Published: January 2025

Um dos principais acontecimentos intelectuais na obra de Leo Strauss foi o encontro decisivo com os pensadores que integraram o Esclarecimento filosófico medieval. A partir disso, Strauss ganhou uma perspectiva crítica em relação ao pensamento moderno. Ele adquiriu clareza sobre o sentido original da filosofia política clássica, que fundamentou os pensadores medievais, e desenvolveu um insight sobre o método de leitura esotérico. Logo, a interpretação straussiana da filosofia política medieval é de importância para os estudos straussianos, em particular, mas também para a teoria e história das ideias políticas, de modo mais geral. Diante disso, o artigo tem como objetivo analisar o contexto intelectual em que Strauss se deparou com os pensadores medievais e investigar qual a substância da filosofia medieval, segundo o autor. Como método, adota uma abordagem histórico-contextual e se concentra na interpretação textualista das principais fontes, incluindo cartas, conferências, artigos e livros de Strauss, contando com o apoio de comentadores relevantes. De especial interesse para o estudo é a interpretação straussiana de Farabi e Maimonides. Concluímos que o diálogo de Strauss com o pensamento medieval se desenrola em meio ao seu confronto com as premissas da filosofia política moderna. Além disso, esclarecemos que Strauss interpreta os sábios medievais como herdeiros diretos de Platão e Aristóteles que desdobram uma análise cético-política da religião e da vida humana em comunidade. Ao buscar o diálogo crítico entre pensamento antigo e moderno, argumentamos, por fim, que o pensamento de Strauss é uma rica fonte para reflexão sobre a tradição e o universo espiritual e político em que vivemos.