bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPACT OF BIODIESEL AGROINDUSTRY ON THE ACHIEVEMENT OF NATIONAL ENERGY SECURITY
Authors: Firdaus Alfa , Machfud Machfud , Suryani Ani , Achsani Noer Azam
Published: April 2020

The National Energy General Plan (RUEN) has set 11.6 million kiloliters of biodiesel production target in 2025. The determination of biodiesel production targets in RUEN is part of the objectives mandated in the National Energy Policy (KEN), which is to achieve energy security and independence. Therefore, this study aims to analyze the impact of biodiesel agroindustry on the achievement of national energy security in 2025. The simulation conducted in this study uses Long-range Energy Alternatives Planning (LEAP) software, which based on the accounting model. The model has run on Business as Usual (BAU) scenario, using four dimensions and 12 indicators of energy security in the context of biodiesel agroindustry. Model simulation results show a decreasing energy security trend in the period of 2022-2025, while the biodiesel production target, which was set at RUEN, cannot be achieved in 2025. This is mainly related to availability and affordability, which experienced a decline in the period. Further research needs to be done on the strategy of developing biodiesel agroindustry by considering scenarios of increasing production capacity and productivity as well as its impact on national energy security.
EDUCATIONAL CHALLENGES FACING SWEDISH PHYSICAL EDUCATION TEACHING IN THE 2020s
Authors: Redelius Karin , Larsson Håkan
Published: April 2020

Muitos países pelo mundo vivenciaram uma virada neoliberal que fortemente afetou seus sistemas educacionais. Na Suécia, por exemplo, o Estado de Bem-Estar social-democrata foi radicalmente transformado desde a década de 1990, tomando uma direção neoliberal. Numerosas reformas educacionais foram realizadas, sendo estas descritas como as mais extensas em 100 anos do ensino público. Essas mudanças também afetaram a disciplina Educação Física e Saúde (PEH). Há um crescente interesse acerca desse tema e a PEH se tornou uma das áreas mais exploradas da cultura de movimento sueca. Os objetivos deste artigo são indicar as pesquisas recentes, bem como identificar e formular possíveis mudanças educacionais que professores enfrentam hoje enquanto caminhamos em direção à década de 2020. As questões centrais são: o que caracteriza o ensino em PEH? O que os estudantes aprendem nessa matéria? Existe eficácia na avaliação da PEH sueca?
A CULTURA DO LIVRO E A PÓS-GRADUAÇÃO EM EDUCAÇÃO FÍSICA
Authors: Manoel Edison De Jesus
Published: April 2020

A crise na cultura do livro foi analisada com base em suas causas e implicações para a formação e avaliação na pós-graduação em Educação Física. Destacou-se a convergência entre a cultura do livro e a universidade de qualidade. Como forma de promover a cultura do livro propõe-se a noção de biblioteca como projeto de autoria considerando que a produção literária constitui um percurso formativo no qual se destacam a liberdade e a autonomia acadêmica.
Simulation-based design of solar photovoltaic energy generation system for manufacturing support
Authors: Medojevic Milana , Medojevic Milovan , Diaz Villar
Published: April 2020

Having in mind that energy is being regarded as indispensable to the socio-economic progress of developing and developed nations, where the main objective implies replacement and reduction of a major portion of the fossil fuels utilization, implementation of renewable energy technologies where natural phenomena are transformed into beneficial types of energy are becoming more and more appreciated and needed. Among renewable energy resources we know today, solar energy is the most beneficial, relatively limitless, effective, and dependable. Having this in mind, the aim of this paper is primarily to help key decision-makers understand the process when considering integration of solar energy to meet their own manufacturing energy needs, or how it is called today, to become ?prosumers?. Given the aforementioned, this paper provides an overview of detailed simulation methodology for photovoltaic system sizing and design for metal-forming manufacturing system energy needs. The simulation is based on National Renewable Energy Laboratory photovoltaic performance model which combines module and inverter sub-models with supplementary code to calculate a photovoltaic power system?s hourly AC output is given a weather file and data describing the physical characteristics of the module, inverter, and array. Furthermore, the characteristic losses are calculated and presented for a fixed array photovoltaic system and illustratively given in the form of a Sankey diagram. A variety of graphical data representations are available while the most important ones are given in the study. Lastly, future research topics were filtered and briefly summarized.
Selection of low temperature thermal power cycles
Authors: Pandey Mukundjee , Padhi Biranchi , Mishra Ipsita
Published: April 2020

In today?s world, we are facing the problem of fossil fuel depletion along with its cost continuously increasing. Also, it is getting difficult to live in a pollution free environment. Solar energy is one of the most abundantly and freely available form of energy. Out of the various ways to harness solar energy, solar thermal energy is the most efficient as compared to photovoltaic technology. There are various cycles to convert the solar thermal energy to mechanical work, but Kalina cycle is one of the best candidates for high efficiency considerations. Therefore, the authors have proposed a novel Kalina cycle having the double separator arrangements to increase the amount of ammonia vapors at the inlet of turbine, and hence have tried to minimize the pumping power for double separator Kalina cycle by reducing the fraction of gas/vapors through it. Here, in this paper we have tried to compare ORC, Brayton cycle, and double separator Kalina cycle for low temperature heat extraction from parabolic trough collectors having arc-circular plug with slits. The effect of different operating conditions, like the number of parabolic trough collectors, mass-flow rate of fluids in different cycles, pressure difference in turbine are analyzed. The effect of these different operating conditions on different parameters like net work done, heat lost by condenser, thermal efficiency and installation cost per unit kW for double separator Kalina cycle, ORC, and Brayton cycle are studied.
Pulsed laser-assisted synthesis of defect-rich NiFe-based oxides for efficient oxygen evolution reaction
Authors: Cai Mingyong , Pan Rui , Liu Weijian , Luo Xiao , Chen Changhao , Zhang Hongjun , Zhong Minlin
Published: April 2020

To develop highly efficient and low-cost electrocatalysts based on earth-abundant elements for oxygen evolution reaction (OER) is a great challenge for electrocatalytic water splitting. Herein, a unique type of NiFe-based oxide catalyst with abundant defects is successfully synthesized via pulsed laser ablation in a specific atmosphere containing reductive NH3. The catalyst is self-supported and assembled from ultrafine nanoparticles with size of less than 5 nm. X-ray diffraction, transmission electron microscopy, and x-ray photoelectron spectroscopy analyses suggest that the reductive NH3 results in a large number of oxygen and nickel vacancies and lower crystallinity. Consequently, the catalyst exhibits a high-performance OER activity with a low overpotential of 223 mV at 10 mA cm−2 and a small Tafel slope of 35.0 mV dec−1, surpassing most NiFe-based OER electrocatalysts.
On the influence of TiB2, TiC, and TiN hard particles on the microstructure of localized laser dispersed AISI D2 tool steel surfaces
Authors: Spranger Felix , Schirdewahn Stephan , Kromm Arne , Merklein Marion , Hilgenberg Kai
Published: April 2020

The control of friction and wear is a major concern in many industrial applications. A promising method for tailored surface modification is the so-called laser implantation technique. This method combines surface texturing and material optimization in one processing step by a localized dispersing of hard ceramic particles using pulsed laser radiation. Wear resistant, protruding micrometric features (implants) with defined geometry can be created in a deterministic pattern where needed on highly stressed surfaces, i.e., on forming or cutting tools. However, in order to maintain the implants over the tool’s lifetime, a suitable selection of hard ceramic particles is a prerequisite. They must provide a defect-free metal matrix composite with a high share of homogeneously distributed particles and, especially, high implant hardness. In this study, TiN, TiC, and TiB2 hard particles were compared as implant materials for the first time. By a systematic variation of pulse power and pulse duration, their dispersing behavior and influence on the material properties of AISI D2 tool steel were investigated. Although all powder materials had grain sizes smaller than 10 μm, it was possible to disperse them by pulsed laser radiation and to obtain defect-free protruding implants. The highest share of dispersed particles (∼64%) was observed for TiB2. By scanning electron microscopy and energy dispersive x-ray spectroscopy, it was also shown that a significant share of the preplaced particles was dissolved by the laser beam and precipitated as nanometer sized particles within the matrix during solidification. These in situ formed particles have a decisive influence on the material properties. While the TiN and TiC implants have shown maximum hardness values of 750 and 850 HV1, the TiB2 implants have shown the highest hardness values with more than 1600 HV1. By x-ray diffraction, it was possible to ascribe the lower hardness values of TiC and TiN implants to high amounts of retained austenite in the metal matrix. By implanting TiB2, the formation of retained austenite was successfully suppressed due to the in situ formation of TiC particles, which was proven by electron backscatter diffraction. In conclusion, all the implant materials are basically suitable for laser implantation on AISI D2 tool steel. However, TiB2 has shown the most promising results.
Some Features of the Direct and Inverse Transformation of Random Variables
Authors: Kosobutskyy P. , Ferens М. V.
Published: April 2020

Always actual tasks of obtaining and processing experimental results in complex systems. Random obstacles (errors), measurement errors, imperfections and limitations of mathematical models and data processing algorithms can change the appearance of the distribution and lead to incorrect use of algorithms, for example, as is the case with Kalman filtering in control systems. Complex methods for the identification of distribution laws require the study of quantum systems, natural phenomena, environmental, biological, etc. processes, which are characterized by the presence of singularities and multimodality of distributions. Therefore, it is often not recommended to apply separate distribution laws to simulate probabilistic experimental data distributions, but a generalized distribution as a single statistical system, which known distributions include as individual partial cases. Thus, the generalized gamma distribution includes Rayleigh, Maxwell, Weibull, Levy, Hi-Square distributions, which are widely used in applied problems associated with statistical methods of physical processes research, remote sensing, in the theory of reliability, for describing the dispersion composition of particles fragmentation and calculation of the efficiency of phase separation in gas-liquid streams.
Пограничные опухоли яичников у беременных
Authors: Герасимова А. А. , Шамаракова М. В. , Клименко П. А.
Published: April 2020

Пограничные опухоли яичников характерны для женщин репродуктивного периода, более чем у трети больных опухоли выявляют в возрасте 15–29 лет, средний возраст при первичной постановке диагноза составляет 40 лет. Целью исследования было усовершенствовать методы диагностики пограничных опухолей яичников на фоне беременности и определить возможности выполнения органосохраняющего лечения. Обследовано 300 беременных с различными опухолевидными образованиями (ООЯ) и опухолями яичников (ОЯ), из которых 25 имели пограничные эпителиальные опухоли: 22 — серозные, три — муцинозные. До операции проводили УЗИ, определяли концентрацию в сыворотке крови СА-125, sFas, VEGF и IL6. Полученные результаты сопоставляли с морфологическими исследованиями. Проводили органосохраняющее и радикальное хирургическое лечение, при необходимости — химиотерапию. При перекрестном сравнении изучали перинатальные исходы. Обнаружено, что различить доброкачественные опухоли яичников от пограничных (ПОЯ) и злокачественных (ЗОЯ) возможно с помощью УЗИ и логрегрессионных моделей. Уровни VEGF выше 500 пг/мл, IL6 выше 8,1 пг/мл и СА-125 выше 300 ЕД/мл свидетельствуют о высокой вероятности ЗОЯ у беременных. И только морфологическое исследование тканей яичников, полученных независимо от хирургических способов, давало истинное представление о характере опухоли яичников у беременных. Вместе с тем у трех беременных с ОЯ при морфологическом исследовании выявлены участки ткани, характерные как для ПОЯ, так и для ЗОЯ. Таким образом, преобладание начальных форм опухолевого процесса, относительно благоприятное течение и прогноз при ПОЯ позволяют достаточно широко использовать хирургическое лечение щадящего характера с сохранением менструальной функции и фертильности.
STOCHASTIC DOMINANCE ON FTSE INDEX
Authors: NISTOR Ioan-Alin , CIUPAC-ULICI Maria-Lenuta , GHERMAN Mircea-Cristian , BEJU Daniela-Georgeta
Published: April 2020

Stochastic dominance is a method that refers to a set of relations, which may hold between a specific pair of distributions. However, the concept can be applied in many domains, but in particular in financial economic areas, where the considered distributions are usually those of random returns to different financial assets. The aim of this paper is to provide an implementation of a stochastic dominance algorithm that establish which of more risky indices is preferred more by investors who have an aversive risk profile. The study is performed on FTSE indices. The focus is to emphasis the imbalance between FTSE regional indices and FTSE sectorial indices. The analyzed period for regional indices is April 3, 2000 –September 12, 2014. As regards the sector indices, the analyzed period is January 3, 1994 – September 12, 2014.Its relevance consist in that, it offers a different perspective for investors when choosing between different financial assets. This approach together with Meyer algorithm has been proved that it is a useful tool in risk aversion analysis.
JEL Classification: C73, D9, D53.
TOURISM INDUSTRY EVOLUTION IN CASE OF BULGARIA AND ROMANIA
Authors: MURESAN Manuela Liliana , POPA Raluca Andreea
Published: April 2020

Tourism is not only a fast expanding global industry, but also a bridge that brings closer cultures and civilizations. The present paper proposes to analyse the tourism sector and environment in the case of Bulgaria and Romania, two countries with high potential in terms of tourism yet unexplored, comparing the two countries from the economic and social perspective. The main objective of the research is to identify the main differences between the two countries and to make recommendations for the development of the tourism sector. The results obtained should show a similarity between the two countries in terms of tourism, as well as the economic and social impact of policies on the evolution of the tourism industry.
JEL Classification: J40, J62, L83, R41, Z33
Rumah ramah rubella sebagai kelompok dukungan online di facebook
Authors: Andreas Rino , Kusuma Rina Sari
Published: April 2020

Situs jejaring sosial dapat membentuk interaksi sebuah komunitas atau kelompok dukungan online (KDO). KDO merupakan komunitas yang dibentuk dengan tujuan yang sama terkait topik tertentu. Kelompok ini tidak terbatas tempat, waktu, ideologi, status sosial, ekonomi maupun pendidikan. Oleh karena itu, interaksi di dalamnya jauh lebih fleksibel karena bisa berhubungan kapan saja dan dari mana saja. KDO sangat berguna untuk menghubungkan individu dengan orang-orang lain yang memiliki masalah kesehatan serupa. Salah satu bentuk KDO dalam situs jejaring sosial adalah grup Facebook Rumah Ramah Rubella. Penelitian ini bertujuan mengetahui pemanfaatan grup Facebook oleh Rumah Ramah Rubella sebagai kelompok dukungan online. Jenis penelitian yang digunakan dalam penelitian ini yaitu kualitatif dengan menggunakan pendekatan analisis isi kualitatif. Sumber data diambil dengan menggunakan teknik purposive, yakni 809 postingan wall dan komentar pada grup Facebook Rumah Ramah Rubella yang dihitung secara manual, selama dua bulan periode kampanye imunisasi MR di Indonesia yaitu Agustus sampai September. Teknik analisis data yang digunakan adalah teknik analisis isi kualitatif menggunakan data koding dengan kategorisasi induktif. Hasil penelitian yang ada dalam grup Facebook menunjukkan bahwa fitur grup Facebook berupa status, gambar, video maupun akses file, bermanfaat dalam sarana dukungan sosial secara online berupa dukungan informasi, dukungan emosional, ruang terbuka ekspresi diri dan sarana promosi terkait dengan Campak dan Rubella, imunisasi MR, maupun penyakit secara umum.
Derecho, Marxismo y Método
Authors: O´Connell Paul
Published: April 2020

El Derecho es crucial para el mantenimiento y la reproducción del capitalismo. A pesar de que Marx nunca produjo una teoría integral del Derecho, el Estado y los derechos, hay mucho de ello en su trabajo y en la tradición marxista más amplia, que pueden ayudarnos a entender la naturaleza y el rol del Derecho en el capitalismo contemporáneo. Este artículo esboza algunos de los recursos claves desde el interior de la teoría marxista, que pueden ayudarnos a desarrollar una comprensión marxista del Derecho, el Estado y los derechos en la actualidad. Específicamente el foco se centra en la cuestión del método, extrayendo tres hilos claves del propio trabajo de Marx: (i) la importancia del análisis dialéctico materialista, (ii) la naturaleza  históricamente específica y transitoria del capitalismo, y (iii) la centralidad del antagonismo de la lucha de clases. El argumento propuesto aquí, en suma, es que las explicaciones marxistas del Derecho, el Estado y los derechos deberían poner en primer plano de referencia estos puntos analíticos, para hacer inteligible el rol del Derecho, y comenzar a esbozar cómo los movimientos hacia el cambio social fundamental podrían entenderse y ligarse con el Derecho.
Novedades de Jurisprudencia
Authors: Amosa Fernando , Díaz Juan Francisco
Published: April 2020

Novedades de Jurisprudencia.
Ejes para delinear un pensamiento crítico latinoamericano
Authors: Gómez Diego J. Duquelsky
Published: April 2020

El presente trabajo es un paso más de un camino, siempre inacabado, que comenzó como una necesidad docente. Cuando en los cursos de teoría general, introducción o filosofía del derecho, terminaba de presentar los paradigmas tradicionales –iusnaturalismo y positivismo- me resultaba complejo explicar en pocas clases los distintos senderos en que se había desarrollado el pensamiento jurídico a partir de mediados del siglo XX.
Awê de Encantarias: a experiência de um livro vivo com crianças Pataxó
Authors: Castro de Araújo Laura , Ferreira Fonseca Carolina
Published: April 2020

Este é um relato de experiência sobre a construção da história YAMANI, publicada no livro “Kijetxawê Zabelê – Aldeia Kaí”, em 2019, e construído juntamente com as crianças da comunidade pataxó da Aldeia Kaí. O texto parte do processo de construção poético dessa história e se enreda em vivências no território expandido da escola Kijetxawê Zabelê, com o intuito de pensar a presença do imaginário dos encantados entre as crianças da comunidade, assim como refletir sobre a experiência de criação de um livro vivo. O trabalho descreve procedimentos de criação coletiva com as crianças, assim como documenta suas etapas de criação, ao passo em que reflete sobre a escola como espaço expandido da aldeia.
Evaluating the efficiency of the environmental security policy in the Russian regions
Authors: Shkiperova G.T. , Druzhinin P.V.
Published: April 2020

Subject. Considering the existing environmental situation, it becomes especially important for the State to regulate the anthropogenic footprint on the environment in the Russian Federation. Current amendments to the legislative framework for environmental security are intended to ensure the innovative development of regions concurrently with a reduction in adverse environmental effects and more active environmental policy.
Objectives. The research is to devise methodological tools to evaluate the efficiency of environmental policy in regions.
Methods. The research employs qualitative and quantitative methods of economic analysis, including statistical and content analysis, rating, matrix zoning. The dataset proceeds from the Federal State Statistics Service, governmental reports on the current environmental situation and environmental protection in the Russian Federation.
Results. We propose our own approach to evaluating the efficiency of environmental policy. It may help trace the correlation between the quality of strategic documents and changes in environmental indicators for a certain period, flag the challenging areas in terms of the environmental policy implementation and outline possible development paths. The approach extends the list of quantification indicators in line with those ones adopted internationally and presented in the Environmental Security Strategy of the Russian Federation up to 2025. We evaluated the efficiency of the environmental policy referring to the regions of the Northwestern Federal District for the period from 2012–2016.
Conclusions. Having analyzed the evaluation results, most of the Northwestern regions tend to be controversial and ambivalent in setting environmental goals and achieving them. The findings may prove useful as the analytical and data basis for articulating the environmental and economic policy of the regions.
Koulutus ja kollegat pitävät kirjastolaiset kartalla
Authors: Toimitus Signumin
Published: April 2020

STKS tarjoaa mahdollisuuden verkostoitumiseen, ammatillisen osaamisen kasvattamiseen ja vaikuttamiseen. Kirjasto- ja tietopalvelualalla pitäisi puhua tulevaisuudesta – muutoksesta, yhteisestä suunnasta ja uusista teknologioista. 90-vuotiasta seuraa tarvitaan jatkossakin kouluttamiseen, yhdessä tekemiseen ja alan kehityksen seurantaan. Tässä yhteenvetona STKS:n uuden hallituksen vastauksia Signumin tiedusteluun.
Lembaga Jaminan Fidusia: Pasca Putusan Mahkamah Konstitusi Nomor 18/PUU-XVII/2019
Authors: Dinata Ari Wirya
Published: April 2020

Fiduciary is one of the guarantees where the debtor has the right to control and take advantage of the goods that are used as fiduciary security objects. Article 15 paragraphs (1), (2), and (3) of Law Number 42 Year 1999 concerning Fiduciary Guarantee regulates the execution mechanism for fiduciary security objects when the fiduciary giver (debtor) experiences breach of promise to the fiduciary recipient (creditor). So far, the execution mechanism for fiduciary security objects regulated in the Act creates legal uncertainty and harms the debtor's rights. Because it gives too much power to the creditor. The imbalance of power relations between debtors and creditors towards the handling of the problem of breach of contract actually causes an injustice in existing fiduciary institutions. The Constitutional Court, through decision number 18 / PUU-XVII / 2019, tries to return the fiduciary institution to the spirit of equilibrium relations between debtors, creditors, and fair fiduciary guarantees. After the decision of the Constitutional Court Number 18 / PUU-XVII / 2019. Has there been a harmonious power relationship between two legal subjects in fiduciary guarantees. This paper examines the pre and post fiduciary guarantee institutions of the Constitutional Court and analyzes the legal consequences that occur. This paper uses a type of juridical-normative research using primary data and primary, secondary and tertiary legal material. While the analysis method uses qualitative methods
PAJÉ, ENCANTADOS E PROMESSAS NOS ENTENDIMENTOS DE PRÁTICAS RELIGIOSAS INDÍGENAS EM ALAGOAS
Authors: Amorim Siloé Soares
Published: April 2020

O Objetivo desse artigo é expor um sentimento contraditório entre a compreensão genérica dos termos Pajé/Pajelança, associados diretamente ao de Xamã/Xamanismo. A oposição a esses termos foi obtida diretamente por meio de experiências etnográficas entre as etnias indígenas do Alto Sertão Alagoano e por meio de debates estabelecidos em eventos acadêmicos e em outros espaços que reúnem indígenas de outros lugares. Enquanto não foi possível encontrar um estudo teórico sobre o problema aqui apresentado, ambos os termos, Pajé/Pajelança, Xamã/Xamanismo, são colocados, concomitantemente iguais em seu conjunto, pela antropologia e também contrários entre si pelos povos indígenas da região. Debate que, teoricamente, vem sendo diferenciado em seus termos e práticas por indígenas em vários espaços quando suscitado o tema de forma genérica, sem distinção de uso. Já que, para os índios da região, Pajé/Pajelança, Xamã/Xamanismo, não se assemelham entre si. Nesse sentido, procuro expor a noção do entendimento dos termos Pajé/Pajelança a partir de sentidos religiosos representados nos rituais de Promessa aos Encantados. Nesses rituais, as ações do Pajé são configuradas como Pajelança. Para as etnias indígenas em Alagoas, esses termos são acionados enquanto identidade étnica local e se particularizam em cada etnia. Percepção que se opõe aos termos Xamã/Xamanismo, terminologia (práticas) universais que “não dão conta” de explicar a etnicidade latente nas etnias indígenas do Nordeste.
RESENHA DO LIVRO: SENHOR DEUS DA VERDADE
Authors: Souza Mary Katherine Araujo de
Published: April 2020

O livro, publicado pela Editora Mongerismo em 2018, foi escrito pelo filósofo, teólogo e educador Gordon Haddon Clark. Traduzido por Ângela Ricci, Felipe Sabino de Araújo Neto e Marcelo Herberts; prefaciado por John Robbins. Com título em original Lord Godo of Truth and Concerning The Teacher, o livro reúne em um único volume duas obras clássicas que discorre adequadamente sobre o empirismo.
PROFIL KESULITAN BERTANYA PADA PROSES PEMBELAJARAN PERKEMBANGAN HEWAN MAHASISWA PENDIDIKAN BIOLOGI UNIVERSITAS ISLAM RIAU PEKANBARU
Authors: Suryanti Suryanti , Sudarmi Sudarmi , Fadheela Salsabyla
Published: April 2020

This study aims to determined factors of questioning difficulty during learning process on Animal Development study. The type of study was survey, using questionnaire, interview, and documentation as study’s instrument. The population subject of this study was third semester student of Biology Education with total 70 students. Analysis method was using descriptive method. As the result of the study shown that questioning difficulty was affected by internal factor 56,21% categorized as adequately and affected by external factor by 61,14% categorized as high. The percentage of students who created question was 42,86% categorized, as adequately, students who were not raise question 57.14% categorized as adequately. During study process, student who able to make questions was at the level of: level C1 (9.64%), level C2 (67,47%), level C3 (14,46%) and level C4 (1,20%) Keywords: Questioning Difficulty Profiles, Internal and External Factors, Student who raised questions, Student who did not raise question, Question Level C1, C2, C3, and C4, Animal Development Study
Interaction of drugs candidates with various SARS-CoV-2 receptors: an in silico study to combat COVID-19
Authors: Barros Romulo O. , Junior Fabio L. C. C. , Pereira Wildrimak S. , Oliveira Neiva M. N. , Ramos Ricardo
Published: April 2020

The world is currently facing the COVID-19 pandemic caused by the SARS-CoV-2 virus. The pandemic is causing the death of people around the world and public and social health measures to slow or prevent the spread of COVID-19 are being implemented with the involvement of all members of society. Research institutions are accelerating the discovery of vaccines and therapies for the COVID-19. In this work, molecular docking was used to study (in silico) the interaction of twenty-four ligands, divided into four groups, with four important SARS-CoV-2 receptors. The results showed that Metaquine (group 01), antimalarial substance and the anti-HIV antiretroviral Saquinavir (group 03), presented interaction with all the studied receptors, indicating that they are potentials candidates for muti-target drugs for COVID-19.
Fmoc-Compatible and External-Thiol-Free Peptide C-Terminus Alkyl Thioester Formation Using Cysteinylprolyl Imide
Authors: Nakatsu Koki , Yanase Masafumi , Hayashi Gosuke , Okamoto Akimitsu
Published: April 2020

We report an Fmoc-compatible and external-thiol-free method of peptide C-terminus thioesterification with cysteinylprolyl imide. The newly synthesized structure, i.e., cysteinylprolyl-thiazolidinone, provided high conversion and sequence-independent fast kinetics (90 min) in the diketopiperazine thioester formation under relatively mild conditions: pH 6.0, 37 °C. Employing this thioesterification method, we synthesized histone H3.2 bearing K56 acetylation.
The Photoisomerization Pathway(s) of Push-Pull Phenylazoheteroarenes
Authors: Vela Sergi , Corminboeuf Clemence
Published: April 2020

Azoheteroarenes are the most recent derivatives targeted to further improve the properties of azo-based photoswitches. Their light-induced mechanism for trans-cis isomerization is assumed to be very similar to that of the parent azobenzene. As such, they inherited from the controversy about the dominant isomerization pathway (rotation vs. inversion) depending on the excited state (nπ* vs. ππ*). While the controversy seems settled in azobenzene, the extent to which the same conclusions apply to the more structurally-diverse family of azoheteroarenes is unclear. Here, we unravel by means of non-adiabatic molecular dynamics, the photoisomerization mechanism of three prototypical phenyl-azoheteroarenes with an increasing push-pull character. The evolution of the rotational and inversion conical intersection energies, the preferred pathway, and the associated kinetics upon both nπ* and ππ* excitations can be linked directly with the push-pull substitution effects. Overall, we clarify the working conditions of this family of azo-dyes and identify a possibility to exploit push-pull substituents to tune their photoisomerization quantum yield.
In-Silico Drug Repurposing for Targeting SARS-CoV-2 Mpro
Authors: Sharma Shilpa , Deep Shashank
Published: April 2020

COVID-19, caused by novel coronavirus or SARS-CoV-2, is a viral disease which has infected millions worldwide. Considering the urgent need of the drug for fighting against this infectious disease, we performed in-silico drug repurposing. The main protease (Mpro) is one of the best characterized drug targets among coronaviruses, therefore, this was screened for already known drugs, including chemical constituents of Ayurvedic drugs, using docking and MD simulation. The results suggest EGCG, withaferin A and artesunate may act as potential inhibitors of the main protease (Mpro).
Application of Life Cycle Assessment and Machine Learning for High-Throughput Screening of Green Chemical Substitutes
Authors: Zhu Xinzhe , Ho Chi-Hung , Wang Xiaonan
Published: April 2020

The production process of many active pharmaceutical ingredients such as sitagliptin could cause severe environmental problems due to the use of toxic chemical materials and production infrastructure, energy consumption and wastes treatment. The environmental impacts of sitagliptin production process were estimated with life cycle assessment (LCA) method, which suggested that the use of chemical materials provided the major environmental impacts. Both methods of Eco-indicator 99 and ReCiPe endpoints confirmed that chemical feedstock accounted 83% and 70% of life-cycle impact, respectively. Among all the chemical materials used in the sitagliptin production process, trifluoroacetic anhydride was identified as the largest influential factor in most impact categories according to the results of ReCiPe midpoints method. Therefore, high-throughput screening was performed to seek for green chemical substitutes to replace the target chemical (i.e. trifluoroacetic anhydride) by the following three steps. Firstly, thirty most similar chemicals were obtained from two million candidate alternatives in PubChem database based on their molecular descriptors. Thereafter, deep learning neural network models were developed to predict life-cycle impact according to the chemicals in Ecoinvent v3.5 database with known LCA values and corresponding molecular descriptors. Finally, 1,2-ethanediyl ester was proved to be one of the potential greener substitutes after the LCA data of these similar chemicals were predicted using the well-trained machine learning models. The case study demonstrated the applicability of the novel framework to screen green chemical substitutes and optimize the pharmaceutical manufacturing process.
Effect of Surface Structure on Peptide Adsorption on Soft Surfaces
Authors: Cheung David
Published: April 2020

Using molecular dynamics simulations the adsorption of peptides onto nanostructured surfaces, consisting of alternating hydrophilic-hydrophobic stripes, was investigated. The adsorption strength, calculated using metadynamics, was found to decrease as the stripe width gets smaller.
Mumtaz Haidari and his role in Kurdish Newspaper
Authors: Ali Barzan Mohammad , Mohammad Karwan Jawhar
Published: April 2020

In general this Research paper examines the biography and personality of Mumtaz Haidari and his role in the history of Kurdish newspapers. All the aspects of the study are supported by proofs, evidence from different trusted sources. The paper expresses its point of views in a very objective way. In all its arguments the writer supports his views and opinions by different sources, in a genuine attempt of him to present a very clear picture of Mr Haidari in all historical incidents of Kurdish history. The research consists of two sections: The first section sheds light on the life of Mr Haidari. The way he grow up and his works up to the present time. The second section focuses on his role in Kurdish newspepars and all his activities and contributions to this fiend.
History writing by the Kurdis in Iraq (1958-1968) is among the books printed in Kurdish language.
Authors: Rafeeq Bashdar Omar , Kakasur Mohammed Abdullah
Published: April 2020

The issue of writing history by Kurdish authors in Iraq between1958-1968 is analysed and explained which is about those printed books in kurdish written and published by Kurdish authors in Iraq. We have concluded that eight history books were published in Kurdish language from 1958 to 1968. Among them, seven of them were written and published from 1958 to 1962 and only one book was published in 1968. This devision of publishing those books has been due to politicial reasons and the emergence of Ailul revolution in 1961. On the one hand, it was due to the political unrest which was a stumbling block for the writing process for authors. On the other hand, however, it was due to the Aylul revolution that led to the restriction of the writing and publication processes by the Iraqi government. The historeans were peoples of different backgrounds in Kurdistan including politicians, army, religious people, school teachers, poets, and scholars. This show the desire of writing history by peoples of different backgrounds in the Kurdish society. Regarding the academic and scientific quality and the methodology of adopted at that time in writing history books, although it cannot be compared by today’s history books, but it was rather narrative and simple. In addition, very few references were usually used in writing those books. This was due to the fact that the history books authors were not historians.
The Role of New Media in Rising Public Awareness of National Security in Iraqi Kurdistan Region During The War On ISIS
Authors: Mustaffa Abdulkhalq Ibrahim , Khidhir Radwan Ali
Published: April 2020

This study aims to explain the role and impact of news websites in Iraqi Kurdistan region in raising public awareness regarding the dimensions of national security and providing them with important information. In this study the method of content analysis is used to analyzing the news content in (Xendan) website and (K24) website during their coverage of the war on Islamic state. The most important finding in this study are: news websites concerned with different dimensions of national security and the military dimension has received more attention than other dimension.
¿Rehacer el Demos? Entrevista con Wendy Brown
Authors: Raza Sebastián , Vásquez Jorge Daniel , Burgum Samuel , Brown Wendy
Published: April 2020

El presente diálogo con la filósofa y politóloga Wendy Brown, tiene como finalidad contrastar sus indispensables y provocativas ideas con los acontecimientos y problemáticas políticas recientes, enfocándose particularmente en su libro ‘El Pueblo sin Atributos’ (2016) y refiriéndose brevemente a ‘La Política fuera de la Historia´ (2014 [2001])  en el contexto actual. Las preguntas fueron formuladas de manera colectiva y la entrevista fue llevada a cabo vía Skype por Sebastián Raza el 23 de Mayo del 2017. Agradecemos a Wendy Brown por la generosa contribución de su tiempo y por responder a nuestras preguntas de forma directa y clara. Esta entrevista ha sido también publicada en inglés por Theory, Culture & Society.
Hacia una economía-política interseccional del populismo
Authors: Iturriza Rodrigo Adriel
Published: April 2020

Ernesto Laclau concibe al populismo como una lógica de articulación política. Para ello, retoma su trabajo con Mouffe, en el cual ambos trataron de dar cuenta de la construcción un nuevo sujeto político luego de la derrota del socialismo real. Así, desde el giro postfundacional, Laclau construye un entramado teórico que deja de lado, sin embargo, una de las dimensiones fundamentales de cualquier proceso político: sus cristalizaciones institucionales. Asimismo, debido a su intento de dar autonomía a lo político con respecto a lo económico, su perspectiva tiende a suspender el análisis de los condicionamientos socio-estructurales (no solo económicos) sobre el problema de la articulación política. Pero además, al obviar el tema de la construcción de la institucionalidad, deja de lado el análisis de su relación sobre diversas desigualdades sociales históricamente estructuradas e, incluso, intersectadas. El presente artículo tiene por objeto repensar ambas dimensiones del populismo: la articulatoria y la instituyente. En relación al primer asunto, el artículo trabaja el vínculo entre la profundización de la heterogeneidad social a raíz de un cambio en el régimen de acumulación y la lógica articulatoria populista. Desde allí se señala la posibilidad y pertinencia de enlazar el concepto de interseccionalidad al de articulación populista. Respecto a la segunda dimensión, se aborda el debate sobre la forma instituyente del populismo y su relación con los procesos emancipatorios desde ideas de una economía-política interseccional.  Del artículo se desprende, en primer lugar, la posibilidad teórica de pensar la emergencia de un pueblo intersectado como sujeto político a partir de repensar el vínculo entre las demandas democráticas. En segundo lugar, se presentan dos líneas de investigación para abordar la potencia emancipatoria de una lógica instituyente populista en clave interseccional: el impacto de las instituciones populistas sobre diversas desigualdades imbricadas y la apropiación de estas instituciones por los subalternos para luchar contra su condición de dominación.
Tagxedo: Media Penulisan Teks Deskriptif
Authors: Harared Nico , Utomo Fajar Wahyudi
Published: April 2020

Tujuan dari penelitian ini adalah untuk memberikan solusi lain dalam hal menarik minat  penulisan teks deskriptif terhadap pengajar di PKBM 10 Guntur dan 11 Manggarai dengan menggunakan aplikasi tagxedo. Peneliti juga menjelaskan kepada para pengajar tentang langkah-langkah pengajaran dengan menggunakan aplikasi ini. Pengajar dalam hal ini menggunakan tagxedo diarahkan untuk membuat satu teks deskriptif. Tagxedo diperkenalkan kepada pengajar dengan mengklasifikasikan kelas kata yang berkaitan dengan teks deskriptif seperti kata benda dan kata sifat. Dengan tagxedo tampilan kata- kata akan tersebar dalam aplikasi ini dan akan membentuk sebuah bentuk yang menakjubkan dengan tampilan gambar yang telah tersedia pada template aplikasi gambar tagxedo. Di samping itu, melalui cara pengajaran ini diharapkan dapat menambah pengalaman belajar yang baru bagi para pengajar. Penelitian ini adalah penelitian tindakan kelas yang dilakukan di PKBM 10 Guntur dan 11 Manggarai. Total pengajar kedua lembaga tersebut sebanyak 19 orang dimana mereka adalah yang dijadikan objek dalam penelitian ini. Pengumpulan data dilakukan dengan observasi dari masing-masing tahap penelitian. Hasil penelitian menunjukan adanya peningkatan kemampuan dalam menulis teks deskriptif bahasa Inggris. Hal ini bisa dilihat dari banyaknya jumlah teks deskriptif dari masing-masing kelompok belajar dan testimoni yang disampaikan pada saat kegiatan berakhir.
Pemberdayaan Kelompok Wanita Tani Melalui Transfer Teknologi Pengendalian Organisme Pengganggu Tanaman Ramah Lingkungan
Authors: Apriliyanto Eko
Published: April 2020

Kegiatan usahatani yang dilakukan oleh Kelompok Wanita Tani (KWT) Dwi Lestari Banjarnegara yaitu budidaya tanaman secara organik. Salah satu kendala yang ada yaitu kerusakan yang ditimbulkan oleh organisme pengganggu tumbuhan (OPT) tersebut tidak hanya mengurangi kualitas hasil tanaman, tetapi ada juga yang sampai membuat tanaman tidak berproduksi. Permasalahan yang dihadapi KWT Dwi Lestari adalah: (1) KWT Dwi Lestari belum memiliki pengetahuan dan keterampilan tentang teknologi pengendalian OPT ramah lingkungan, (2) KWT Dwi Lestari belum memiliki pengetahuan tentang pemanfaatan bahan-bahan alami di sekitarnya sebagai bahan atau sumber pengendali OPT. Metode yang digunakan dalam kegiatan ini yaitu transfer teknologi melalui pemberdayaan anggota KWT dengan pemberian materi dan kuisioner tentang pengendalian OPT ramah lingkungan. Sebelum kegiatan dilaksanakan, peserta melaksanakan pre-test tentang pengendalian OPT. Selanjutnya peserta menyimak paparan dari pemateri yang dilanjutkan dengan diskusi dan kunjungan di lahan. Akhir kegiatan dilaksanakan post-test untuk mengetahui kemampuan peserta setelah pemberian meteri. Rerata hasil pre-test yaitu 56,32 sedangkan hasil post-test yaitu 80,00. Tingkat pengetahuan peserta sebelum dan sesudah dilaksanakan transfer teknologi menunjukkan pengaruh pengingkatan pengetahuan bagi seluruh peserta. Semangat tinggi dari seluruh peserta sudah menjadi modal untuk kemajuan kelompok ini. Kegiatan pemberdayaan KWT masih perlu yang lebih terintegrasi seperti pembuatan media tanam organik, pembuatan pupuk organik, pembuatan pestisida nabati, dan pembuatan pestisida hayati.
Penerapan Metode Total Physical Response (TPR) dalam Pengajaran Bahasa Inggris di TK
Authors: Ekawati Anita Dewi
Published: April 2020

Mengajar Bahasa Inggris sebagai bahasa asing bukanlah hal mudah, terutama pengajaran Bahasa Inggris untuk anak usia dini. Guru diharapkan selalu memiliki ide kreatif dan inovatif untuk menarik perhatian siswa dalam kegiatan pembelajaran di kelas agar siswa dapat mengerti mengenai materi yang diajarkan. Total Physical Response (TPR) adalah salah satu metode yang dapat diterapkan. TPR adalah sebuah metode yang menggunakan gerak tubuh untuk mengartikan kata. Tujuan diadakannya pelatihan menggunakan metode ini adalah untuk membantu guru mengajar Bahasa Inggris dan menciptakan suasana kelas yang menyenangkan. Metode ini mudah diaplikasikan untuk guru-guru di TK ‘Aisiyah 101 Cipayung dan TK ‘Aisiyah Bustanul Athfal Ciracas. Peserta yang hadir sebanyak 12 orang terdiri dari Kepala Sekolah dan guru. Metode yang digunakan antara lain 1) pemberian materi tentang TPR mengenai teori dan contoh-contoh dengan power point dan video, 2) penugasan kepada peserta secara berkelompok untuk mencari tema dan mempraktekan TPR, 3) bimbingan dan diskusi mengenai TPR yang dipraktekan. Hasil dari kegiatan ini seluruh peserta bersemangat dan dapat menggunakan metode TPR dengan baik.
Edukasi Adopsi Standar Mutu Berbasis Indikasi Geografis pada Petani Kopi di Kabupaten Temanggung
Authors: Ihsaniyati Hanifah , Setyowati Nuning , Wijaya Adhitya Pitara
Published: April 2020

Persaingan pasar dalam agribisnis kopi robusta semakin ketat. Karakteristik mutu kopi yang khas, unik dan tampil beda yang terindikasi karena pengaruh faktor geografis dapat dimanfaatkan untuk meningkatkan daya saing. Indikasi Geografis (IG) memiliki peranan penting untuk menarik minat konsumen dengan cara memberikan nilai tambah dan keunikan pada komoditas kopi. Namun, adopsi IG oleh petani kopi relatif rendah, demikian halnya adopsi IG oleh petani kelompok MPIG Kopi Robusta Kabupaten Temanggung. Edukasi mengenai manfaat, proses, kendala dalam adopsi IG diperlukan untuk memotivasi petani kopi dalam adopsi IG. Kegiatan ini bertujuan untuk memotivasi petani kopi dalam adopsi standar mutu berbasis IG melalui edukasi IG. Metode yang digunakan antara lain pelatihan, studi banding dan pendampingan adopsi IG. Hasil kegiatan pelatihan menunjukkan bahwa petani telah memahami manfaat dan kendala serta tahapan proses panen dan pasca panen berbasis IG. Melalui studi banding ke P4S Semarang, petani kopi juga termotivasi mengadopsi IG. Kegiatan pendampingan yang dilakukan oleh tim dan pemerintah mendorong petani semakin antusias dalam mengadopsi IG.
On the Involute of the Cubic Bezier Curve by Using Matrix Representation in E3
Authors: KÄ±lÄ±Ã§oÄŸlu Åžeyda , Åženyurt SÃ¼leyman
Published: April 2020

In this study we have examined, involute of the cubic Bezier curve based on the control points with matrix form in E3. Frenet vector fields and also curvatures of involute of the cubic Bezier curve are examined based on the Frenet apparatus of the first cubic Bezier curve in E3.Â Â
Asymptotic Solutions of Scalar Integro-Diï¬€erential Equations with Partial Derivatives and with Fast Oscillating Coeï¬ƒcients
Authors: Kalimbetov Burkhan , Temirbekov Akisher , Tolep Abdimuhan
Published: April 2020

In the paper, ideas of the Lomov regularization method are generalized to the Cauchy problem for a singularly perturbed partial integro-differential equation in the case when the integral term contains a rapidly varying kernel. Regularization of the problem is carried out, the normalÂ and unique solvability of general iterative problems is proved.
JOB-SHOP SCHEDULING OPTIMIZATION WITH STOCHASTIC PROCESSING TIMES
Authors: Alzahrani Jaber
Published: April 2020

In this study, a job shop scheduling optimization model under risk has been developed to minimize the make span. This model has been built using Microsoft Excel spreadsheets and solved using @Risk solver. A set of experiments have been also conducted to examine the accuracy of the model and its effectiveness has been proven.