bluuebunny/crossref_metadata_2025 huggingface dataset:
Teaching strategies for resolving gastrointestinal function from the perspective of cell biomechanics
Authors: Qian Bo , Qin Zihao , Liu Shuo , Wan Fuzhen , Yu Rui
Published: December 2024

Traditional gastrointestinal function teaching focuses on biochemical and physiological regulation, but fails to explore the effects of mechanical forces on gastrointestinal cell behavior and function, resulting in students’ one-sided understanding of gastrointestinal function. This paper proposes a new teaching strategy by combining cell biomechanics with teaching to help students master the gastrointestinal function mechanism more comprehensively. First, the membrane elasticity of gastrointestinal smooth muscle cells is measured. The elastic modulus is calculated by combining the Hertz model and the applied force is controlled to avoid cell membrane damage. Elasticity change data is obtained. Then, a flexible substrate is used to apply stretching and low frequency to simulate the mechanical force of cells during peristalsis and monitor the fluctuation of calcium ion concentration. Then, the distribution of intercellular cadherin is analyzed, and mechanical force is used to accelerate the permeability of gap junctions and the expression of Connexin43 to promote signal transmission. Finally, a teaching experiment based on cell biomechanics is designed, covering cell culture, mechanical stimulation, quantitative analysis and molecular biology verification, to help students understand how mechanical forces affect gastrointestinal cell behavior and function. The results show that before and after the application of the cell biomechanics teaching strategy, the students’ test scores increase by 16%, and the experimental results are good. Applying biomechanical factors into teaching by combining teaching strategies with cell biomechanics has a positive effect on medical education.
Produção científica e características organizacionais em unidades de terapia intensiva brasileiras: um estudo transversal multicêntrico
Authors: dos Santos Thiago Tavares , de Azevedo Luciano César Pontes , Nassar Junior Antonio Paulo , Salluh Jorge Ibrain Figueira
Published: December 2024

RESUMO Objetivo: Examinar as associações entre a produção científica das unidades de terapia intensiva brasileiras e suas características organizacionais. Métodos: Trata-se de uma reanálise de uma coorte retrospectiva anterior, que avaliou as características organizacionais das unidades de terapia intensiva e suas associações com os desfechos. Analisamos dados de 93 unidades de terapia intensiva em todo o Brasil. As unidades de terapia intensiva foram avaliadas quanto à produtividade científica e aos efeitos de suas atividades de pesquisa, usando indicadores de assistência para comparação. Definimos as unidades de terapia intensiva mais produtivas cientificamente como aquelas com várias publicações e escore SCImago Journal Rank ou índice h acima dos valores medianos das unidades de terapia intensiva participantes. Resultados: As unidades de terapia intensiva com mais publicações, pontuações SCImago Journal Rank mais altas e escores índice h mais altos tinham número maior de intensivistas certificados (mediana de 7; IIQ 5 - 10 versus 4; IIQ 2 - 8; com p < 0,01, na comparação entre unidades de terapia intensiva com mais e menos publicações). As unidades de terapia intensiva com pontuações SCImago Journal Rank e índice h mais altas também tiveram um número maior de protocolos totalmente implementados (mediana de 8; IIQ 6 - 8 versus 5; IIQ 3,75 - 7,25; p < 0,01, na comparação entre unidades de terapia intensiva com pontuações SCImago Journal Rank mais altas versus mais baixas). Conclusões: O trabalho científico foi associado a melhores padrões de pessoal e a maior implementação de protocolos, sugerindo que a atividade de pesquisa pode ser um indicador de melhor organização da unidade de terapia intensiva e da prestação de assistência.
Análise de como os componentes do escore SOFA variam ao longo do tempo em sua contribuição para a mortalidade
Authors: Lam Barbara D. , Struja Tristan , Li Yanran , Matos João , Chen Ziyue , Liu Xiaoli , Celi Leo Anthony , Jia Yugang , Raffa Jesse
Published: December 2024

RESUMO Objetivo: Determinar como cada componente de órgão do escore SOFA difere em sua contribuição no risco de mortalidade e como essa contribuição pode variar ao longo do tempo. Métodos: Realizamos uma análise de regressão logística multivariada para avaliar a contribuição de cada componente de órgão no risco de mortalidade no primeiro e sétimo dia de internação em unidade de terapia intensiva. Usamos dados de dois conjuntos de dados públicos, a eICU Collaborative Research Database (eICU-CRD) (208 hospitais) e a Medical Information Mart for Intensive Care IV (MIMIC-IV) (um hospital). Calculamos a razão de chances de cada componente do SOFA, que contribuiu para a mortalidade. A mortalidade foi definida como morte na unidade de terapia intensiva ou dentro de 72 horas após a alta da unidade de terapia intensiva. Resultados: Foram incluídas 7.871 internações em unidades de terapia intensiva da eICU-CRD e 4.926 internações em unidades de terapia intensiva da MIMIC-IV. A disfunção hepática foi a mais preditiva de mortalidade no primeiro dia em ambas as coortes (RC 1,3; IC95% 1,2 - 1,4; RC 1,3; IC95% 1,2 - 1,4, respectivamente). Na coorte eICU-CRD, a disfunção do sistema nervoso central foi a mais preditiva de mortalidade no sétimo dia (RC 1,4; IC95% 1,4 - 1,5). Na coorte MIMIC-IV, a disfunção respiratória (RC 1,4; IC95% 1,3 - 1,5) e cardiovascular (RC 1,4; IC95% 1,3 - 1,5) foram mais preditivas de mortalidade no sétimo dia. Conclusão: O escore SOFA pode ser uma simplificação exagerada de como a disfunção de diferentes sistemas de órgãos contribui para a mortalidade ao longo do tempo. São necessários mais estudos em uma escala de tempo mais granular para explorar como o escore SOFA pode evoluir e ser aprimorado.
Changes in central venous pressure during a fluid challenge have limited value for guiding fluid therapy
Authors: de Oliveira Priscilla Souza , Ramos Fernando José da Silva , Tomotani Daniere Yurie Vieira , Machado Flávia Ribeiro , de Freitas Flávio Geraldo Rezende
Published: December 2024

ABSTRACT Objective: To evaluate whether changes in central venous pressure during fluid expansion and baseline cyclic respiratory variation in the central venous pressure amplitude (RespCVP) curve could be used to discriminate between fluid responders and nonresponders. Methods: This prospective observational study included critically ill adult patients who underwent fluid expansion in the form of a fluid bolus or fluid challenge with crystalloids. All patients were under mechanical ventilation and adequately sedated. We determined the central venous pressure at baseline (CVPT0) and the changes at 5 (ΔCVPT5), 10 (ΔCVPT10) and 15 (ΔCVPT15) minutes during fluid infusion. We also measured the RespCVP at baseline. Fluid responsiveness was defined as a cardiac index increase of ≥ 15%. Results: The study included 30 patients (11 responders and 19 nonresponders). The CVPT0 and the changes after a fluid challenge at all three time points did not adequately predict fluid responsiveness, as determined by their area under the curve values (CVPT0: 0.70, (95%CI: 0.49 - 0.90; ΔCVPT5: 0.78, (95%CI: 0.57 - 0.99; ΔCVPT10: 0.63, (95%CI: 0.39 - 0.88; ΔCVPT15: 0.68, ((95%CI: 0.45 - 0.92). The RespCVP at baseline also had a poor performance (area under the curve: 0.70; 95%CI: 0.50 - 0.91). Conclusion: Changes in central venous pressure have limited value in predicting fluid responsiveness.
Critical Analysis of Public Health Preparedness and Multisector Collaboration in Crisis Management
Authors: Alismail Abdullah Mujahid Abdullah , Aboun Moraya Mubark Ali , Al yami Mohsen Hussein Ali , Al Rashah Ahmad Saleh R , Mashahhim Ibrahim Hussain Ali , Alyami Saleh Mobark , Alsalamah Salem Fahad Mohammed , Alsalamah Mohammed Fahad Mohammed , Abdli Abdullah Hussain , ALRashah Rashed Fahad Rashed
Published: December 2024

It has become clear that preparedness and management of crises have also become important issues regarding natural disasters, epidemics, and other related calamities. This review systematically examines the existing approaches and models to prepare public health collaboratively, with special attention to intersectoral integration. Intense cooperation between representatives of the governmental and non-governmental levels, healthcare institutions, and the private sector is the key to success in crisis management. The present review enlists examples regarding recent outbreaks, such as cases, assets, liabilities, and opportunities for reflection. The purpose will be to reveal the best practices that would help improve public health systems’ abilities to address future challenges through the lens of multisector collaboration and preparedness framework development.
Comprehensive Review of Technological Integration in Nursing Workflows: Balancing Innovation and Patient-Centered Care
Authors: Alnasser Almuhannad Saleh , Alenazi Nurah Onazan Mahal , Almnahy Sulaiman Ibrahem Abdulziz , Alnasser Almuayyadsa Saleh Ali , Balobaid Abeer Mubarak , Al mautairi Abdulaziz fahad masha , Alharbi Athei Obed N , Alwadaeen Fahad Abdullah Fahad , Alenzi Anwar Onayzan Mahal , Al-Harbi Sulaiman Ali
Published: December 2024

The advanced application of technology in nursing has greatly impacted the present healthcare delivery process by improving the efficacy, precision, and safety of nursing. Technological advancements, including EHRs, telehealth, AI, and robotic systems, have caused shifts in the usual functions of nurses. However, these technologies have unique considerations that must be balanced with patients’ needs and values. This review is intended to raise and discuss questions regarding the development and use of technologies in the nursing practice environment, their benefits and drawbacks, and the conflict between the enhancement of technology adoption and the fundamental values of the nursing profession. This review of the current literature, as well as several empirical works and some cases, reveals the benefits and the challenges for nursing professionals regarding the use of technologies. This review also provides suggestions for improving how technology is implemented into nursing processes to develop effectiveness in a functional organization and improve patient care quality.
Comprehensive Review of Nurses’ Role in Chronic Disease Management: Collaborative Care Approaches
Authors: Al aateibi Bader Shgaa , Sadoun Manal Mohammed , Alnuaimi Noora Rabeea , Alghamdi Suad Abdaullah Saleh , Alharthi Mesfer Fahad Awaidh , Khayat Hafsah Mohammed , Almatrafi Raghad Jameel Saleh , Falattah Miad Mohammed Bakor , Ridha Wael Abdullah Ahmad , Albariqi Nabilah Ahmed Amer , Saeed Nouf Ali
Published: December 2024

Diabetes, hypertension, and heart diseases, as well as others, are common diseases that affect a large number of people around the globe today. Such diseases call for rational and integrated approaches across specialists to achieve the best patient results. Chronic illness care involves education of the patients, effective coordination of care, and management of symptoms, which are major areas that involve the input of the nurses. This review focuses on nursing interventions in chronic disease and the importance of the collaborative care model in nursing. Therefore, observing how the incorporated nursing skills in an interdisciplinary process influence the quality of patients’ lives with chronic diseases, the review examines the communication processes, evidence-based practice, and patient-centered approach. Highlights focus on the benefits of the involvement of nurses, including effective disease management, increased patient satisfaction, and improved health. The review also discusses the hurdles of nursing as a profession, such as having to contend for resources and emphasizing the continuous development of professional skills, before it presents specific recommendations for enhancing nursing stakeholders’ contributions to managing chronic diseases.
Comprehensive Review of Pharmacist-Driven Medication Therapy Management: Improving Patient Safety and Compliance
Authors: Balhareth Ibrahim Mohsen Salem , Al shalan Mohammed Ahmed Mohammed , Alshehri Abdullah Mahdi Mohammed , Alshehri Abdullah Mohammed Abdullah , Alshehri Dhafer Mohammed Dhafer , Alshahrani Abdullah Ali Saeed , Al rashadi Saeed Mohamad Rashadi , Alqahtani Faris Hussain Ali , Alhudaisan Thamer Mohammed , Alwadai Abdullah Mahdi Jobran
Published: December 2024

Medication therapy management is a critical service that involves medication reviews, patient education, and care management to enhance patients' therapeutic processes.  The presence of pharmacists as easily available healthcare professionals who specialize in the use of drugs and medication is vital in avoiding causes of medication risks and complications, medication compliance, and better outcomes for patients’ health. This review will discuss the involvement of pharmacists in MTM, the advantages or disadvantages of using the technique, patient safety, and noncompliance. We also review how MTM interventions conducted by pharmacists are being practiced and evaluated in the present literature, their strengths and weaknesses, and the future direction of this practice.
Critical Review of Healthcare Policy Reforms and Their Impact on Health Outcomes across Socioeconomic Groups
Authors: Alqahtani Safar Mohammed Mushabab , Alqahtani Sultan Abdullah Hussain , Asiri Fahad Yahya Mohammed , Asiri Ali Abdullah Yahya , Asiri Tariq Ahmed Hassan , Asiri Mohammed Ali Mohammed , alqhtani Mofareh Tourkey Mohammed , Al Mawtah Mohammed Ibrahim Binali , Alzabadani Mansour Ali Hamad , Balhareth Ali Abdulkarim Ali
Published: December 2024

Universal healthcare policy changes are vital in the fight against differentiated healthcare debts along the line of provision. Stakeholder activities seek to enhance reception, costs, and quality of treatment; nevertheless, effectiveness differs based on other factors, for example, execution modalities, funding, and targeted populace. It discusses and analyzes healthcare policy reforms across countries and compares the results of their impact on health status and the equity in utilization and benefits received by people of different socioeconomic statuses. It also looks at how the use of technology and public-private partnerships enhances equity in health care delivery.
Critical Review of Redefining Diagnostics: The Integration of Laboratory Excellence with Health Administration for Improved Outcomes
Authors: Al Garea Ali Saleh Mohammed , Alqufayli Mubarak Mohammed Saad , Balharith Hamad Abdullah Mubarak , Alsagoor Hadi Fais Mohammed , Al bakri Ibrahim Abdullah Yahya , Albaltaheen Dhafer Amer , Alsari Mansour Ali Gaseem , Alofair Mohammed Ali Hussein , Almuhamidh Alhassan Saleh Hadi , Almahmeed Hadi Saleh Hadi
Published: December 2024

The coupling of lab diagnostics with health administration may become the key pivot point for endorsing health care. Combined with accurate policy formulation and supervisors’ monitoring and control, precision diagnostics can improve disease prevention, management, and patients’ clinical outcomes. This paper aims to review the place of laboratories in health care delivery, the advantages of cooperation, and the difficulty of integration. It underlines key insights, worldwide examples, and new trends as to how laboratory information can be used for planning and decision-making in managing healthcare organizations.
Critical Analysis of Healthcare Policy Reform: Addressing Systemic Inequities and Advancing Universal Health Coverage
Authors: Al zmanan Abdullah Hadi Mana , Al monif Abdullah Hamed Hadi , Al zmanan Salih Yahia Salih , Alshehri Fahad Mohammed Jaber , Alshehri Mohammed Amer Ahmed , Alakkasi Faris Ibrahem Abduallah , Asiri Abdulaziz Awad Malahi , Alzubaidi Abdulelah Hezam Ali , Alshehri Mohammed Ghaithan Ghurman , Atiah Hassan Ibrahim Mohammed
Published: December 2024

Healthcare policies have now emerged as important programs globally, especially considering various systemic issues that affect health inequalities for the poor. Healthcare policy reform has now become a critical consciousness globally. As mentioned in the section of the paper, goals, and objectives, following this brief discussion on the targeted inefficiencies and inequities seeking UHC reforms, this paper aims to offer a critical analysis of the reforms that aimed at fulfilling the above-mentioned goals of these changes. There is an implementation gap in UHC globally even though it was designed to ensure that every human being gets access to healthcare services when needed, but they should not be forced to pay for the services Lime and Thorlacius (2017). This paper analyzes the differences between nations with insufficient systems by looking at successful UHC models and comparing them to those of the US, such as Canada, the UK, and Brazil. It also examines new directions in healthcare policies based on new technologies, including digital health, PPPs, and other financing schemes that have been demonstrably effective in removing obstacles to UHC. In assessing these issues about contemporary humanitarian policies and health status, this paper outlines the opportunities and challenges in advancing global healthcare equity. That is why the goal is to outline additional policy reforms based on the literature analysis that can help eliminate inequalities regarding healthcare accessibility, quality, and efficiency.
Critical Review of Nursing Innovations in Emergency Care and Chronic Disease Management
Authors: Al Shamlan Ali Bardan Mana , Almoyed Abdullah Hasan , Almahboob Neamah Saad Saeed Saad , Alshria Sabra Hamad Mahdi , Al Htrash Bashair Mohammed Awad , Al-Geshanien Mahdi Makhfoor , Balhareth Huda Abduilah Mohamad , Al Swar Awad Musfer Masloom , Alfaraj Abdullah Awadh , Almota Mohmmed Hussin
Published: December 2024

This paper critically reviews innovations in nursing practice within two essential domains of healthcare: aesthetics, acute & emergency care, and the treatment of chronic illnesses. The nursing profession has responded to the continuing expansion of these areas directed toward enhancing patients' status, cost containment in the healthcare sector, and the general quality of care. In emergency care, innovations like the triage system, nurse-led emergency care, and the application of advanced technologies in assessing and managing emergency patients have revolutionized emergency care. Nursing in the care of chronic illness has described new roles in disease prevention, patient education, and chronic illness care with the use of new technologies and interventions to enhance the overall health of patients with chronic health conditions. This review looks at recent innovations in nursing, assesses their utility, and weighs their application to emergency and chronically ill patient populations or nursing.
Public Health Strategies for Managing Pandemics: Lessons Learned from Systematic Reviews of Recent Global Crises
Authors: AATI MOHAMMED HAMAD AHMED , WARQASH ABDULMOHSEN MASOUD ALI AL , ZELAEI NAWAF ABDULRAHMAN , JAHSHAR ABDULRAHMAN YAHA ABDULLAH , ALGHAMDI EBTESAM IMBARAK SAFAR , MUSHAHHIM MOHAMMED ALI ALI , ALGHAMDI ABDULRAHMAN FAISAL MOHAMMED , ALTHOBAITI AHMED GHAZI SAHAL , ALWADIE ABDULLAH HASSAN HUSSEIN , ALSAGOOR ALI SALEH
Published: December 2024

Crisis control is daunting for any public health system worldwide, particularly in pandemics. As new acute infections continue to be identified, practicable, effective measures are important to reduce damage and facilitate healing. Against this background, this paper explores systematic reviews of pandemic responses, predominantly the COVID-19 outbreak, the Ebola outbreak, and the H1N1 influenza pandemic intervention. When combined, the result of the reviews used in this paper is the recognition of effective interventions, including early warning systems, isolation, vaccination, and healthcare infrastructure improvement. It also looks at working conditions during such crises, such as scarcity of commodities, rumors, and disparity in receiving healthcare in LMICs. Perhaps most importantly, these pandemics have provided insights into the course that future pandemics should/should not take by pointing to the importance of preparedness, cooperation, and communication. Finally and principally, this review is intended to guide public health interventions and improve control of subsequent pandemics by boosting health systems and organizational collaboration and promoting universal health access. This paper argues that there should be readiness and enhanced international collaboration if sentimental-related diseases are to be prevented.
Comprehensive Review of Pharmacogenomics and The Expanding Scope of Pharmacy Practice in Precision Medicine
Authors: Almoyed Gassim hassan Mohammed , Alsharif Hamzah Khaled M , Alshareef Ahamed Mohammed , Alofair Saeed Ali Hussain , Al yaseen Mansour Mohammed , Yaseen Hamad Mahdi Faris , Aldosari Ahmad Samran Ali , Al shareef Ali Mohammed Hussein , Alaglah Moslah Hussain Moslah , Alhashel Ibrahim Saleh Hamad
Published: December 2024

This review aims to examine the relevance of understanding pharmacogenomics to develop precision medicine and the broadening role of pharmacy in this field. Pharmacogenomics, the study of genetic factors affecting drug action, has emerged as an essential component in clinical practice, thus providing individualized therapy. The paper aims to provide a background of pharmacogenomics, identify its current use in healthcare, and discuss the possibility of pharmacies incorporating and enhancing drug therapy. It considers such issues as pharmacogenomics/pharmacy bottlenecks, potential benefits, and consequences for patients, and the costs and responsibilities of the pharmacists and pharmaceutical organizations for pharmacogenomic-based treatments. The review's author provides suggestions for merging pharmacogenomics even more into clinical practice and pharmacy education.
Management And Administration: Comprehensive Review of Governance Models and Organizational Adaptability in Health Systems
Authors: Alshareef Ali Hussain Mohammed , Alabbas Khaled Hadi , Al-Daghrir Saleh Ahmed Ali , Alshareef Ali Alhassan Ali , Alsharif Naji Saud Naji , Alsharief Ibrahim Abdullah , Alshrief Abdullah Hassan , Alsharif Hussain Yahya Obud , Al faran Mahdi Hussein Mesfar , Alshareef Ali Abdullah Abdulwahab
Published: December 2024

Healthcare systems and organizational change, together with governance models, remain vital to understanding the stability of health systems. This review further looks into the various forms of governance in the healthcare systems in different countries across the globe, with the effects of these governance models on the system's performance examined. Lastly, organizational flexibility is also considered when availing health systems for emerging health challenges. Discussing centralized, decentralized, and hybrid governance models, the paper evaluates the strengths and weaknesses of the corresponding approach. Furthermore, it also points out the chief trends of the evolving healthcare system and the emergence of a more adaptable and responsive culture, particularly in the era that has experienced pandemics. The review also discusses the opportunities for technology use, public-private partnerships, and workforce training to enhance the organization's resilience to health systems. Implications of the present study are that good governance, combined with a well-coordinated and adaptable system, augments health, productivity, and access for the public. The review ends by recommending better governance structures, flexibility, and system issues in healthcare delivery.
Comprehensive Analysis of Innovations in Post-Surgical Pain Management and Patient Rehabilitation
Authors: Alsharif Nasser Ali , Alsharif Ahmad Alhassan , Alshareef Khalid Hasan , Aldouh Mohammad Douh , Almansour Hussain mana , Al Sharif Zayed Mohammed, , Alshareef Yahya Alhassan Ali , Alshareef Rabeiallah Nasser , Alsharif Rakan Khaled Mohammed , AL-Zawaid Hassan Mohsen Ali
Published: December 2024

Post-surgical pain management and patient rehabilitation play crucial role in identifying factors explaining postoperative pain, thus reducing the risk of complications, prolonging the healing process, and enhancing the patient’s quality of life during rehabilitation. These are non-opioid analgesics, minimally invasive procedures, multimodal pain management, and digital health interventions because they enhance outcomes and diminish risks of opioid-based pain management where traditional methods were applied. The findings of contemporary research studies are integrated in this paper to focus on the effectiveness, the difficulties, and the opportunities of offered changes for the practices of clinical medicine.
تبیین جامعه‌شناختی از سبک زندگی غربی (با رویکرد انتقادی)
Authors: امانی گلابشاه
Published: December 2024

سبک زندگی؛ نگرش‌ها، ارزش‌ها و رفتارهایی است که اعضای جامعه با آن زندگی می‌کنند. وجود آسیب‌ها و مسایلی در سبک زندگی، می‌تواند سلامت، اخلاق، امنیت و آرامش فردی و جمعی را تهدید نماید. با این‌حال، هر جامعۀ دارای سبک زندگی خاص خود است. برخی جوامع از جمله غرب بنابه دلایل متعددی از جمله حفظ نظم موجود جهانی و تداوم هژمونی فرهنگی، اقتصادی و سیاسی خود در تلاش ترویج و گسترش سبک زندگی غربی در جوامع دیگر بوده‌اند. مسأله مهم این است که سبک‌ زندگی غربی دارای آسیب‌ها و مسایل است که حتی محافل علمی خودشان سال‌هاست بدان معترف‌اند. از جانب دیگر، بنا به دلایلی این سبک زندگی در کشورهای مختلف از جمله در افغانستان نیز نفوذ کرده و الگوگیری‌های از آن انجام می‌شود. بنابراین هدف اصلی این تحقیق، معرفی و شناسایی مسایل سبک زندگی غربی و آگاه‌سازی مردم و به‌خصوص جوانان از مسایل این سبک زندگی است. این تحقیق با رویکرد کیفی، به مرور نظامند نظریه‌ها و تحقیقات مرتبط پرداخته، و با روش تحلیل مضمون اطلاعات را تحلیل و تجزیه کرده است.
تأثیرگذاری فعالیت‌های بازاریابی داخلی بر عناصر تعهد سازمانی
Authors: مایار نصیراحمد , غفورزی همایون , امانی شفیع الله
Published: December 2024

سازمان‌ها با توجه به تغییرات امروزی جهان باید خود را به‌صورت داخلی و خارجی همسو نماید. بنابراین، در بحث بازاریابی قبل از این‌که فعالیت‌ها در خارج از سازمان به اجرا درآید، لازم است در داخل سازمان صورت گیرد و ذریعه آن بتوانیم تعهد کارمندان را افزایش دهیم، بنا بر اهمیت این موضوع، هدف از تحقیق حاضر مطالعه تأثیرگذاری فعالیت‌های بازاریابی داخلی بر عناصر تعهد سازمانی می‌باشد. داده‌های تحقیق با استفاده از پرسش‌نامه‌های معیاری بازاریابی داخلی و تعهد سازمانی جمع‌آوری شده است. جامعه آماری این تحقیق تمام کارمندان دایمی یک نهاد تحصیلات عالی خصوصی و حجم نمونه با استفاده از جدول مورگان به‌دست آمده است. روش تحقیق از نوع توصیفی و از نظر هدف کاربردی می‌باشد. یافته‌های تحقیق نشان‌دهنده تأثیرگذاری مثبت فعالیت‌های بازاریابی داخلی بر عناصر تعهد سازمانی به ترتیب R=0.542 بالای تعهد عاطفی، R=0.501 بالای تعهد هنجاری و R=0.402 بالای تعهد مستمر می‌باشد.
study of EFL Students' Argumentative writing skills through online collaborative writing activities
Authors: Saksopin Utumporn , Kaweera Chittima , Yawiloeng Rattana
Published: December 2024

This study explored the impact of online collaborative writing on EFL students' argumentative writing abilities and their attitudes toward using this method to enhance their skills. The participants consisted of twenty undergraduate students from a writing classroom at the University of Phayao, selected through purposive sampling. The twenty students were categorized into three proficiency levels: advanced, intermediate, and novice learners. The selected participants were then divided into 5 heterogeneous groups to collaboratively compose argumentative paragraph writings. This study, employing a mixed-methods approach, combines both quantitative and qualitative techniques. The instruments consisted of six lesson plans, pre-test and post-test, 4 argumentative writing assignments, a semi-structured interview, and a questionnaire. The study evaluated an online collaborative writing activity to determine how proficiency levels affected both group and individual writing performance. The results of the students' argumentative writing post-test were higher than their pre-test scores across all proficiency levels. The highest scores in students' argumentative writing were found in the group performance, followed by the individual post-test scores, respectively. The semi-structured interview showed that online collaborative writing activities improve argumentative writing by promoting group brainstorming, idea sharing, and critical thinking. This approach enhances students' analysis, evaluation, and content-creation skills, leading to more effective group work. Additionally, online collaborative writing simplifies tasks like gathering information and using various functions, making the writing process more efficient.
Analisis Kandungan Serat Kasar Pada Tepung Porang
Authors: Anggela Anggela  , Yamaysyah Salma Nabila  , Rahmatia Ananda  , Eris Pransiscah Nainggolan  , Wahyu Wahyu  , Asrul Asrul
Published: December 2024

Porang flour, extracted from the tuber of the porang plant (Amorphophallus muelleri), is known as a food ingredient rich in fiber and low in calories. This study aims to measure the crude fiber content in porang flour tested at the Food and Agricultural Product Technology Laboratory, Faculty of Agricultural Technology, Universitas Gadjah Mada. Based on the analysis, the average crude fiber content in porang flour was found to be 0.79%, with a standard deviation of 0.02%. However, no crude fiber content was found in the porang flour gel sample. These findings provide important insights into the potential of porang flour as a fiber source in the development of food products. The results also demonstrate product quality consistency, which can serve as a foundation for the development of healthier food industries.
Etnobotani Tumbuhan Beluntas (Pluchea Indica) sebagai Tanaman Obat di Kampung Bojong Salam, Kecamatan Banyuresmi Garut
Authors: Hilwa Kamilatunnuha  , Tri Cahyanto
Published: December 2024

This study discusses the use of beluntas plants (Pluchea indica) as medicinal plants in Bojong Salam Village, Banyuresmi District, Garut. Ethnobotany investigates the interaction between people and plants, particularly in the context of traditional medicine. The people of Bojong Salam Village have long used beluntas plants as medicine to treat body odor, bad breath, back pain, and vaginal discharge. This study involved interviews with 30 respondents using a purposive sampling method. In data analysis, quantitative and qualitative approaches were used, including calculating the Use Value (UV) and Fidelity Level Index (FIC). The results showed that beluntas leaves had the highest UV value of around 0.5 and FIC of around 50% as a medicine for vaginal discharge, followed by other benefits as a medicine to eliminate body odor, bad breath and back pain. The results showed that beluntas is an important plant in traditional medicine used by the people of Bojong Salam Village.
Krajina detstva Jana Vladislava – literárne návraty do rodného mesta
Authors:   Filozofická fakulta Univerzity sv. Cyrila a Metoda v Trnave, Kamenčík Marián
Published: December 2024

This article discusses the hometown of Jan Vladislav (born Ladislav Bambásek), Hlohovec, in south-west Slovakia, during Vladislav’s youth and also the one time he visited it as an adult. The main subject of analysis will therefore be Vladislav’s two short autobiographical prose works: ‘Galgócz MDCLXXXIII’ and ‘Návraty, domovy’ (Returns, homes). In this connection we discuss the socio-cultural background of the town, which influenced the young Ladislav and formed him in his early childhood. Expressing a special symbolic perception of the topography of the town, Vladislav’s writing is a fascinating source of his reflections on the value of centre and periphery, stability and change, the eternal and the temporary, as well as other contrasts, whose main motif is often the river. The author also considers Vladislav’s views on the phenomenon of one’s home in relation to one’s birthplace, while considering his often-presented idea that home exists in time, not in space. This memoir-fiction thematically set in Hlohovec creates a special epic space filled with objects and populated with figures, which represent the world of Vladislav’s childhood, set its rules, and symbolize or metaphorically express profoundly experienced moments. It is this world the article examines and seeks to understand by considering the author’s literary recollections.
Municipal green bonds : climate finance amidst climate injustices
Authors:   , Herrera Héctor
Published: December 2024

The climate finance mobilization agenda represents one of the key global responses to the ongoing climate crisis. A dominant discourse within this agenda promotes the idea that by attracting private capital, public authorities and private actors can accelerate the green transition and support initiatives labeled as climate action, including both mitigation and adaptation measures. Green bonds, a green-labeled type of debt instrument issued in financial markets, represents one of the fastest-growing strategies within this agenda. This dissertation offers new qualitative and empirical insights about green bonds from a climate justice perspective. It addresses the overarching question of how municipal green bonds, as instruments of climate finance, engage with climate action (both adaptation and mitigation), and interact with local and global climate injustices. To explore this question, the dissertation is structured around three interlocking triads: three case studies, analyzed through the three pillars of climate justice, across three research phases. Therefore, this doctoral thesis investigates the issuance and materialization of municipal green bonds in the cities of Cape Town (South Africa); Mexico City (Mexico); and San Francisco (United States). It applies the Intergovernmental Panel on Climate Change’s (IPCC) definition of climate justice as the analytical framework grounded in the pillars of procedural justice, recognition, and distributive justice, examining the green bonds through the phases of green labeling, project implementation, and the narratives that emerge around these bonds. This study achieves three key objectives. First, it identifies the impacts of water infrastructure projects financed by municipal green bonds, with particular emphasis on issues of uneven water distribution and environmental racism. Second, it reveals three previously underrecognized dimensions of climate vulnerability (race, income, and gender) within the context of water infrastructure financed by municipal green bonds. Third, it provides an analytical portrait of the positive narratives of climate action that are associated with municipal green bonds issuance. It argues that these narratives tend to prioritize financial performance and the achievement of quantitative targets while overlooking the climate justice implications and the complexities of the underlying socio-economic contexts. In conclusion, this dissertation contributes to a deeper understanding of the expanding role of municipal green bonds in climate finance, the implications of their use for climate action, and their limitations in addressing and responding to climate injustice at the local level.
‘But fiction does not necessarily mean not true' : perceived (non-)fictionality and narrative engagement
Authors:   , Ghasseminejad Melina
Published: December 2024

Academics and the general public often find themselves speaking about engagement when discussing narratives. As readers, we talk about being transported to the storyworld, immersed in the narrative and getting lost in the book. Sometimes, our engagement with narratives evokes a childlike wonder. We recognise ourselves in the characters, sympathise with their struggles and experience various emotions alongside them. Moreover, research has shown that these effects are stronger when people read fictional novels as opposed to non-fictional texts. This presents an exciting avenue of research: does the perception of fictionality affect narrative engagement? In other words, if two different readers are given an identical text, but one is told that the text is fictional and the other non-fictional, will that change their responses and affect their narrative engagement? To explore this question of perceived fictionality, I designed an experiment in which actual readers were interviewed to establish whether their perception of a narrative as fictional or non-fictional influenced its reception. To this purpose, Storyworld Possible Selves (SPSs) Theory was used as a framework with James Frey’s book A Million Little Pieces serving as the text material. The experiment involved interviews with twenty-four participants divided into three equal groups, each assigned to one of three conditions: Fiction, Non-Fiction, Control. Before reading excerpts from the book, participants in the Fiction group were told that the text they were given was fiction, the Non-Fiction group was told the text was non-fiction, and the Control group was given no such information. In short, this dissertation focused on people’s responses and perceptions when reading a narrative. The results indicate that the readers in the study who read the provided narrative as fiction displayed the emergence of a larger number of SPSs and, thus, exhibited higher levels of narrative engagement. Furthermore, the results show a strong connection between individuals’ self-concepts – or who they believe to be – and their narrative engagement, suggesting that familiarity with the text’s topic enhances narrative engagement. In summary, the findings suggest that fictionality affects the construction of SPSs to some extent and provides strong support for the enlightening potential of SPSs Theory in studying how fictionality can influence narrative engagement. Additionally, the findings confirm that while perceptions of (non-)fictionality may act as a contributing factor, the reader’s self-concept also plays an essential role in the creation of SPSs and, therefore, in narrative engagement.
Elucidation of the clinical relevance and potential mechanisms of persistence in Streptococcus pneumoniae
Authors:   , Geerts Nele
Published: December 2024

Infectious diseases exist already for millennia and so does antimicrobial therapy. The past 100 years, major advances were accomplished into the fight against infectious diseases, especially with the discovery of antimicrobial agents. Unfortunately, these discoveries were accompanied with the fast emergence of antimicrobial resistance. Many efforts were made regarding research into antimicrobial resistance, but bacteria can evade antibiotic treatment also in different ways resulting in therapy failure. One way of how bacteria can evade killing by antibiotics, regardless of resistance, is antibiotic persistence. Persister cells are phenotypic variants that exist as a subpopulation within a clonal culture and can transiently switch to a nongrowing state that enables them to survive treatment with a bactericidal drug concentration. Being tolerant to lethal antibiotics, they underly the chronic nature of a variety of infections and even help in acquiring genetic resistance. Streptococcus pneumoniae is a common colonizer of the mucosal surfaces of the nasopharynx of children, but can also cause life-threating diseases like pneumonia, sepsis and meningitis. S. pneumoniae remains a major cause of morbidity and mortality worldwide, despite the availability of a vaccine, and is classified as a priority pathogen by the World Health Organization (WHO) in 2024 for the need of novel antibiotics. Many reports were published about antibiotic persistence in a variety of bacterial species, but for Streptococcus pneumoniae, no studies were published. We were the first to report the presence of persisters in S. pneumoniae cultures for different clinically relevant, bactericidal antibiotics (amoxicillin, cefuroxime, moxifloxacin and vancomycin) using our optimized long-living in vitro model. We detected high persister levels for S. pneumoniae reference strain D39 varying according to the growth phase and the antibiotic. Experimental evolution did not lead to the formation of a highly persistent phenotype which hampered us to investigate the molecular mechanisms behind S. pneumoniae persistence. Furthermore, we employed a large set of S. pneumoniae clinical isolates to prove the clinical relevance of S. pneumoniae persistence as persister cells were widely present in our strain collection. Finally, we made the first steps for the optimization of a long-term in vivo model to enable persistence studies in a clinically relevant setting. Altogether, our work advocates for higher interest for persistence in S. pneumoniae as a contributing factor for therapy failure and resistance development.
Designing a LINE OA HR bot to support human resources management between company employees and outsourced staff
Authors: Jitgosol Yuvadee , Udomdej Boonraksa
Published: December 2024

This study presents a method for Thai international airline contractual workers in the vicinity of the Ubon Ratchathani Airport to get to classes punctually. To effectively train outsourced employees, this research intended to design a LINE Official Account (LINE OA) HR bot as a tool to support human resources management between company employees and outsourced staff. Initially, this study was qualitative, using case studies executed to reveal the problem of missing training courses and what can be accomplished in a practical setting. A cohort of 7 persons was chosen, comprised of key informants including both regular employees and outsourced workers. An individual in-depth interview form was used as a research method, and the case study was created using descriptive analysis of the results. Therefore, a LINE OA HR bot was developed and tested on users for each interviewee position to determine whether or not it could be used to resolve problems at the next step. The results of the research are that the LINE OA HR bot replied swiftly and with accurate, complete, accessible, and comprehensible information. Additionally, it offered a shortcut menu that aided the outsourced staff with other inquiries and an option to seek a personal meeting with the administrator, which improved the effectiveness of cooperation between the companies.
FUERTE OLIMPO: "FORJANDO UNA HISTORIA DEL ALTO CHACO"
Authors: Farías Federico
Published: December 2024

En el vasto territorio paraguayo, donde las imponentes llanuras del Chaco se extienden sin fin, se encuentra Fuerte Olimpo, una ciudad que ha forjado su historia a sangre y fuego, a la sombra de colosales árboles y bajo el ardiente sol chaqueño. Fundada en 1792 como Fuerte Borbón, esta urbe fronteriza ha sido escenario de batallas épicas, expediciones intrépidas y la incansable lucha por la conquista del Chaco Boreal. Desde sus inicios, Fuerte Olimpo estuvo envuelta en un torbellino de eventos que la convirtieron en escenario de cruentos enfrentamientos y heroicas hazañas. La Guerra de la Triple Alianza (1864-1870) dejó una huella imborrable en la ciudad. A principios del siglo XX, Fuerte Olimpo se convirtió en el punto de partida de la épica campaña para conquistar el Chaco Boreal, un territorio en disputa con Bolivia. La Guerra del Chaco (1932-1935) fue un conflicto sangriento y prolongado que puso a prueba la resistencia y el valor del pueblo paraguayo. Fuerte Olimpo sirvió como base militar estratégica, desde donde se lanzaron las ofensivas que finalmente dieron la victoria a Paraguay. Más allá de su pasado guerrero, Fuerte Olimpo es un crisol de culturas donde se mezclan las tradiciones indígenas, españolas y paraguayas. La influencia de los pueblos originarios, como los Chamacocos, se refleja en su artesanía, gastronomía y cosmovisión. La herencia española, por su parte, se manifiesta en la arquitectura colonial y las celebraciones religiosas. Y la identidad paraguaya impregna cada rincón de la ciudad, desde su música vibrante hasta su cálida hospitalidad. A pesar de los desafíos que ha enfrentado a lo largo de su historia, Fuerte Olimpo sigue siendo un faro de esperanza en el corazón del Alto Chaco. Sus habitantes, orgullosos de su pasado y resilientes ante las dificultades, trabajan incansablemente por el desarrollo y el progreso de la ciudad. Fuerte Olimpo es un ejemplo de la tenacidad humana y la capacidad de superar los obstáculos más difíciles. Este prólogo no sería completo sin rendir un homenaje a los héroes que han forjado la historia de Fuerte Olimpo. A los soldados que lucharon con bravura en las FUERTE OLIMPO 11batallas, a los exploradores que se adentraron en lo desconocido, a los líderes que guiaron a su pueblo con sabiduría y determinación. A todos ellos, nuestro más profundo respeto y admiración. Recorrer las calles de Fuerte Olimpo es como viajar a través del tiempo. En cada esquina se respira la historia, en cada rostro se refleja la fortaleza de su gente, en cada paisaje se revela la belleza indómita del Chaco. Esta ciudad es un museo viviente que nos invita a conocer su pasado, comprender su presente y vislumbrar su futuro. Fuerte Olimpo es un destino imperdible para aquellos que buscan conocer la verdadera esencia del Paraguay, un país de contrastes, de héroes anónimos y de una belleza natural sin igual. Es un lugar que te conmoverá con su historia, te sorprenderá con su cultura y te cautivará con su calidez. Ven a descubrir Fuerte Olimpo y déjate llevar por la magia del Chaco.
ЕXOTIC WORDS AND THEIR LEARNING
Authors:   K.Tynystanov Issyk-Kul State University, Maksatbek kyzy A.
Published: December 2024

It is known that no language in the world can live without communicating with each other. This process is a legal and normative social phenomenon that was and will be in the language of all peoples.
Exotic words are one of the pressing issues of Kyrgyz linguistics. To understand the nature of this term, it is necessary to delve into the section of lexicology from which the words are taken. The lexical composition of the language is changeable. It is known that some words go out of use, and new words enter our language. Exotic vocabulary also corresponds to accepted words and introduces the culture of another people. According to the research materials, exotic words in the modern Kyrgyz language are divided into several thematic groups. And this has been studied to a certain extent in Kyrgyz linguistics. The facts are taken from literary translations, dictionaries, encyclopedias. Their semantics is of great importance in teaching exoticisms. In addition to obtaining information about the uniqueness of a people or region, a comprehensive linguistic study of the word is carried out. The article is devoted to these issues.
ON THE QUESTION OF THE APPEARANCE OF THE MAIDEN NAME KANYKEY-SANIRABIGA IN THE VERSION OF THE EPIC "MANAS" BY THE STORYTELLER SAGYMBAI OROZBAKOV
Authors:   Kyrgyz-Turkish Manas University, Mokeev A.
Published: December 2024

The article examines the origin of the maiden name of Manas Kanykey's wife. According to the version of the famous Manaschi storyteller Sagynbai Orozbakov, this name was Sanirabiga, taken from a retelling of a brief and inaccurate translation of the text of the inscription on the wall of Gumbez Manas, made by historian Belek Soltonoev, in the early 20s of the XX century. It is noted that at the same time, Sagimbai sought to expand the number of words of Arabic-Persian origin and strengthen the Muslim plots of his version of the epic associated with the most important center of Islam in Central Asia, the Bukhara Khanate, from where Kanykey herself or pseudo Sanirabiga originated. The cultural and historical contexts that influenced the formation of this name in the epic are also analyzed. Thus, the study of the name of Kanykey highlights the influence of Islamic culture on the Kyrgyz epic and reveals the relationship between the history and literature of the region.