bluuebunny/crossref_metadata_2025 huggingface dataset:
On the Differences in the Periodic Behavior of Magnetic Helicity Flux in Flaring Active Regions with and without X-class Events
Authors: Soós Sz. , Korsós M. B. , Morgan H. , Erdélyi R.
Published: February 2022

Observational precursors of large solar flares provide a basis for future operational systems for forecasting. Here, we study the evolution of the normalized emergence (EM), shearing (SH), and total (T) magnetic helicity flux components for 14 flaring (with at least one X-class flare) and 14 nonflaring (<M5-class flares) active regions (ARs) using the Space-weather Helioseismic Magnetic Imager Active Region Patches vector magnetic field data. Each of the selected ARs contain a δ-type spot. The three helicity components of these ARs were analyzed using wavelet analysis. Localized peaks of the wavelet power spectrum (WPS) were identified and statistically investigated. We find that (i) the probability density function of the identified WPS peaks for all the EM/SH/T profiles can be fitted with a set of Gaussian functions centered at distinct periods between ∼3 and 20 hr. (ii) There is a noticeable difference in the distribution of periods found in the EM profiles between the flaring and nonflaring ARs, while no significant difference is found in the SH and T profiles. (iii) In flaring ARs, the distributions of the shorter EM/SH/T periods (<10 hr) split up into two groups after flares, while the longer periods (>10 hr) do not change. (iv) When the EM periodicity does not contain harmonics, the ARs do not host a large energetic flare. (v) Finally, significant power at long periods (∼20 hr) in the T and EM components may serve as a precursor for large energetic flares.
Estimating the Spin of the Black Hole Candidate MAXI J1659-152 with the X-Ray Continuum-fitting Method
Authors: Feng Ye , Zhao Xueshan , Gou Lijun , Wu Jianfeng , Steiner James F. , Li Yufeng , Liao Zhenxuan , Jia Nan , Wang Yuan
Published: February 2022

As a transient X-ray binary, MAXI J1659-152 contains a black hole candidate as its compact star. MAXI J1659-152 was discovered on 2010 September 25 during its only known outburst. Previously published studies of this outburst indicate that MAXI J1659-152 may have an extreme retrograde spin, which, if confirmed, would provide an important clue as to the origin of black hole spin. In this paper, utilizing updated dynamical binary system parameters (i.e., the black hole mass, the orbital inclination, and the source distance) provided by Torres et al., we analyze 65 spectra of MAXI J1659-152 from RXTE/PCA, in order to assess the spin parameter. With a final selection of nine spectra matching our f
sc ≲ 25%, soft state criteria, we apply a relativistic thin disk spectroscopic model kerrbb2 over 3.0–45.0 keV. We find that inclination angle correlates inversely with spin, and, considering the possible values for inclination angle, we constrain spin to be −1 < a
* ≲ 0.44 at a 90% confidence interval via X-ray continuum fitting. We can only rule out an extreme prograde (positive) spin. We confirm that an extreme retrograde solution is possible and is not ruled out by considering accretion torques given the young age of the system.
Evolution of Highly Magnetic White Dwarfs by Field Decay and Cooling: Theory and Simulations
Authors: Bhattacharya Mukul , Hackett Alexander J. , Gupta Abhay , Tout Christopher A. , Mukhopadhyay Banibrata
Published: February 2022

We investigate the luminosity suppression and its effect on the mass–radius relation and cooling evolution of highly magnetized white dwarfs. Based on the effect of magnetic field relative to gravitational energy, we suitably modify our treatment of the radiative opacity, magnetostatic equilibrium, and degenerate core equation of state to obtain the structural properties of these stars. Although the Chandrasekhar mass limit is retained in the absence of magnetic field and irrespective of the luminosity, strong central fields of about 1014 G can yield super-Chandrasekhar white dwarfs with masses ∼2.0 M
⊙. Smaller white dwarfs tend to remain super-Chandrasekhar for sufficiently strong central fields even when their luminosity is significantly suppressed to 10−16
L
⊙. Nevertheless, owing to the cooling evolution and simultaneous field decay over 10 Gyr, the limiting masses of small magnetized white dwarfs can fall to 1.5 M
⊙ over time. However, the majority of these systems still remain practically hidden throughout their cooling evolution because of their high fields and correspondingly low luminosities. Utilizing the stellar evolution code stars, we obtain close agreement with the analytical mass limit estimates, which suggests that our analytical formalism is physically motivated. Our results argue that super-Chandrasekhar white dwarfs born as a result of strong-field effects may not remain so forever. This explains their apparent scarcity, in addition to making them hard to detect because of their suppressed luminosities.
Study of Tumor Necrosis Factor-Alpha-Induced Protein 3 Gene Single-Nucleotide Variants in JAK2 V617F-Positive Myeloproliferative Disorders: A Case–Control Study
Authors: Abdelghany Wafaa M. , El Husseiny Noha M. , Fekry Gehad H. , Korayem Osama H. , Helmy Rehab
Published: February 2022

Background and Objectives: Myeloproliferative neoplasms (MPNs) are Philadelphia negative disorders involving polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF). Although JAK2 mutation is almost involved, other several mutations are linked to MPNs risk and prognosis. TNFAIP3 genetic mutations are related to several cancers and autoimmune diseases. Our study aimed to demonstrate the effects of rs2230926_T/G & rs5029939_C/G SNVs of TNFAIP3 gene on the risk and prognosis of JAK2 V617F positive MPNs.
Methods: Matched 2 groups in age, sex and race were enrolled in our research; 80 MPNs cases group and 130 normal healthy controls group with follow up of MPNs cases for 3 years.  Taqman assay probes involved in real time polymerase chain reaction (PCR) were utilized for variants analysis.
Results: The rs2230926 & rs5029939 SNVs were in modest linkage disequilibrium (LD) in MPNs cases. The observed frequencies of G allele and its genotypes of both variants were more prevalent in MPNs patients than normal controls. The bleeding symptoms and the presence of splenomegaly were more existent in the heterozygous genotype and the combined G involved genotypes respectively. The overall survival (OS) was lower in G containing genotypes of both variants but the progression free survival (PFS) was affected only in rs5029939 SNV.
Conclusion: Our study revealed the association of G containing genotypes of both rs2230926 & rs5029939 SNVs to the increased MPNs incidence as well to poor clinical course and prognosis of JAK2 V617F positive MPNs disorders in Egyptian ethnic.
Conservation biology meets medical science
Authors: Schmeller Dirk S.
Published: February 2022

In my letter I refer to publications around syndemics, and link them up to other health concepts, calling for a stronger link between medical, social and environmental sciences to advance the global management of pandemic threats. Calling for close collaboration of ecological and conservation sciences with medical sciences is very timely. This letter will raise awareness that concepts like EcoHealth, OneHealth and medical terms such as Syndemics are largely overlapping and that only a comprehensive, multidisciplinary approach will move our understanding forward on the inextricable link of human health and environmental health.
Big Data in Nursing: A Bibliometric Analysis
Authors: Carter-Templeton Heather , Nicoll Leslie , Wrigley Jordan , Wyatt Tami
Published: February 2022

Big data will have a growing role in nursing scholarship requiring parallel growth in data competencies and literacies to benefit nursing practice, education, and policy. This article offers background information about big data and bibliometric analysis, and describes a study that analyzed published research focused on big data in nursing to evaluate trends and understand the current evidence on this topic. Scopus was used as the primary database to retrieve published articles. The study results and subsequent citation analysis of 64 articles from 2014 to 2020 determined the types and extent of literature on big data in nursing, which authors and journals publish big data research, and the origins of the studies that were reviewed. The majority of the articles included offered descriptive or review type scholarly contributions with a clinical practice focus and/or application. Our discussion suggests future directions for research, content about nurse involvement in big data important for nursing curricula, implications for policy action based on evidence, and our assessment of the state of the science. This analysis demonstrated strong interest in big data approaches in nursing literature but little application of these approaches was identified in the represented articles.
An Air Force Nurse Leader’s Impact: Brigadier General Goodwin, 10th Air Force Nurse Corps Chief
Authors: Hughes Victoria
Published: February 2022

To pursue and fulfill the limitless potential of nursing, it is important to recognize and record the stories of previous leaders who helped to pave the way for advances in the nursing scope of practice, clinical expertise, and leadership opportunities. The purpose of this oral history research method study was to preserve and explore the impact and contributions of Brigadier General (Brig Gen) Barbara Goodwin during the evolutionary time from 1988 to 1991. In an extensive interview, Brig Gen Goodwin reflected on her leadership strategies to address the nurse shortage, the advancement of nurse leadership and educational opportunities, and crucial collaboration efforts contributing to the deployment of 40,000 women in support of war efforts. The findings section discusses the leadership themes identified, which included collaboration, prioritization, understanding the system, and a passion for clinical nursing. The conclusion summarizes her significant impact on military nursing.
La lutte contre la précarité alimentaire
Authors: Sèze Benjamin
Published: February 2022

En décembre 2020, le Cocolupa, installé par le ministre des Solidarités et de la Santé, celui de l’Agriculture et de l’Alimentation et celle du Logement, s’est fixé un objectif ambitieux : transformer le modèle français de lutte contre la précarité alimentaire. Et pour cause, depuis le début de la pandémie de Covid-19, au printemps 2020, le nombre de personnes recourant à l’aide alimentaire a explosé, et les images de jeunes faisant la queue pour recevoir quelques boîtes de conserve et des paquets de pâtes ont choqué l’opinion publique.
Pascal, philosophe chrétien ?
Authors: Devillairs Laurence
Published: February 2022

Nous fêterons prochainement l’anniversaire de la naissance de Blaise Pascal. Mais savons-nous exactement qui est cet auteur du Grand Siècle ? un chrétien ? un janséniste ? un moraliste ? un pourfendeur sombre et désespérant de la vanité et de la comédie humaines ? Si nous tentions de lire autrement les Pensées de Pascal pour y découvrir une philosophie ni tragique ni secondaire, ni convenue ni soumise, mais profondément originale et inclassable. Pascal n’appartient à aucune école, ni à aucune chapelle.
L’accueil des patients étrangers à l’hôpital sous le feu croisé des réformes comptables et des politiques d’immigration
Authors: Aron Julien , Geeraert Jérémy , Izambert Caroline
Published: February 2022

Cet article explore les effets croisés et paradoxaux des réformes comptables et des politiques d’immigration sur les pratiques des professionnels hospitaliers dans l’accueil des patients étrangers. À l’aide de données empiriques issues de trois études en sciences sociales (notamment au sein de permanences d’accès aux soins de santé [PASS] et de services de néphrologie), il montre que le contexte hospitalier depuis le début des années 1990 a permis d’affirmer une mission d’accueil envers les étrangers dépourvus de couverture maladie. Cette mission n’a été possible que parce qu’elle s’est accommodée des objectifs de réduction des dépenses hospitalières qui se sont imposés avec force dans l’institution lors de la même période. Si cette évolution a profité aux étrangers les plus proches des critères d’éligibilité de l’Assurance maladie (eux-mêmes fixés par des politiques d’immigration restrictives) qui ont vu leur légitimité à accéder aux soins auprès des soignants s’accroître, elle a eu tendance à favoriser des pratiques discriminatoires et de refus de soins envers les étrangers dont le statut de séjour est le plus précaire.
Les inégalités d’accès aux ressources par les réseaux personnels chez les patients atteints de cancer
Authors: Barthe Jean-François , Defossez Adrien
Published: February 2022

La littérature scientifique a montré que certaines catégories de patients parvenaient moins que d’autres à accéder aux ressources produites par le système de soins, comme l’information de santé par exemple. Nous nous sommes demandé dans quelle mesure l’aide apportée par l’entourage relationnel au cours de la maladie n’est pas soumise elle aussi à de fortes disparités selon les patients. À partir d’une enquête en cours ayant permis l’analyse de 18 parcours de patients atteints de cancer, nous montrons que l’accès aux ressources par les réseaux personnels est très inégal : certains malades vont pouvoir compter sur un entourage leur procurant des ressources nombreuses et variées, quand d’autres vont se retrouver totalement démunis de ce point de vue. Les caractéristiques des réseaux personnels des malades sont décrites ainsi que les types de ressources fournis par l’entourage. L’entourage relationnel, loin de permettre une réduction des inégalités d’accès aux ressources entre patients, participerait au contraire à leur production.
Burnishing of AM materials to obtain high performance part surfaces
Authors: Sanguedolce Michela , Rotella Giovanna , Saffioti Maria Rosaria , Filice Luigino
Published: February 2022

Purpose: This paper aims to provide a flexible solution to include additive manufacturing into a process chain complying with Industry 4.0 pillars, overcoming major drawbacks in terms of reliability and experimental effort.Design/methodology/approach: The study is based on the combination of real experimental activities and simulated ones.Findings: The main findings of this work consist of validation of the proposed process chain, which proves to be effective in terms of process flexibility (additive manufacturing, burnishing and process simulation acting synergistically), cost and time reduction and final output quality, encouraging customer involvement towards customization.Originality/value: This paper contributes to current research on the application of burnishing process, an easy way to implement and environmental friendly post-processing method to improve the performance of AM products, by providing a unique perspective integrating a reliable simulation model. Other researchers can use these outcomes towards manufacturing of the future.
Special Issue: Smart manufacturing for sustainability: Trends and research challenges
Authors: Di Pasquale Valentina , Franciosi Chiara , Iannone Raffaele , Miranda Salvatore
Published: February 2022

This Special Issue of the Journal of Industrial Engineering and Management (JIEM) gathers six papers, which contributed to deepen knowledge in the sustainable Industry 4.0 domain, through the presentation of studies focused on the adoption of smart technologies, methodologies, artificial intelligence techniques, and optimised strategies for a sustainable management of the factories of the future.These papers were selected at the 2020 edition of the International Conference on Industry 4.0 and Smart Manufacturing (ISM 2020), organised by the University of Applied Sciences Upper Austria, Austria, and the University of Calabria, Italy, whose mission is to exchange knowledge and discuss theoretical advances, research results and industrial experiences among researchers and practitioners in the field of Industry 4.0 and smart manufacturing for the digital.
Using a Simulation to Increase Awareness of the Impact of Poverty on Health Care
Authors: Hill Cindy
Published: February 2022

A poverty simulation can increase participants' knowledge of the impact of poverty on patients' health care choices. Professional development specialists can develop poverty simulations for their health care organizations. Planning and delivering a successful simulation requires preparation beforehand to logistically implement a simulation that has a positive, meaningful impact.

[
J Contin Educ Nurs
. 2022;53(2):57–58.]
Teaching Nurse Practitioner Students Advanced Health Assessment Skills During COVID-19
Authors: Walters Colleen P. , Gilliam Stephen , Nguyen Christine A. N. , Joshua Thomas V.
Published: February 2022

The purpose of this project was to evaluate student outcomes before and during the coronavirus disease 2019 (COVID-19) pandemic in an advanced health assessment course that was offered in the summer semesters to nurse practitioner (NP) students as a hybrid course with online didactic and in-person lab components. Due to COVID-19, the summer 2020 course offering transitioned to being 100% online and innovative strategies replaced the in-person labs. Student outcomes from summer 2019, when the course was hybrid, were compared to summer 2020, when the course was changed to being 100% online. The findings of this project showed somewhat similar learning outcomes on both knowledge and skill acquisition in the 100% online course despite the change to 100% online during COVID-19. In teaching advanced health assessment to NP students, use of videography for skills demonstration, the virtual classroom, and unfolding case studies provided a robust and flexible pedagogy approach for 100% online teaching during a pandemic.

[
J Contin Educ Nurs
. 2022;53(2):83–89.]
La dimension spatiale de l’innovation dans les régions périphériques nordiques
Authors: Dubois Alexandre
Published: February 2022

Cet article se propose d’explorer la dimension spatiale des problématiques contemporaines du développement régional dans les zones périphériques nordiques. Historiquement, le développement de ces régions s’est fait sur la base de l’exploitation des abondantes ressources naturelles disponibles, telles que les minerais (fer, cuivre…) ou le bois. Dans une première partie, l’article propose d’introduire un cadrage conceptuel permettant de mieux appréhender la complexité des systèmes de relations entretenues par les acteurs de ces régions. Dans une deuxième partie, l’exemple d’une PME d’une localité minière du Nord de la Suède est utilisé afin d’illustrer comment ce cadrage permet de comprendre les dimensions relationnelle et spatiale de ces processus. Enfin, dans la dernière partie, l’article propose de discuter les récents exemples venus de l’implémentation de la stratégie de la « spécialisation intelligente » permettant d’exposer les défis du développement territorial, notamment en ce qui concerne l’équilibre à trouver entre la gouvernance des ressources naturelles et l’inclusion de ces régions dans l’économie de la connaissance, au travers de la gouvernance territoriale.
La ville suédoise : le triomphe de l’oikos ?
Authors: Filler André
Published: February 2022

Le présent article se propose de dégager des lignes d’évolution de la ville suédoise. Il interroge le particularisme du développement du tissu urbain suédois par rapport au contexte général d’urbanisme européen et scandinave. Après avoir souligné le rôle ambigu de l’agglomération suédoise, juridiquement et administrativement floue, spatialement poreuse par rapport aux zones non urbanisées de la commune, unité administrative en vigueur, sera identifiée la problématique : l’équilibre entre l’esthétique et le social dans la conception urbaine du royaume. Résultat d’urbanisme moderne ou post-moderne, illustration matérielle du modèle social-démocrate ou lieu de tensions et de fonctions atomisées, l’aménagement du territoire urbain en Suède est expliqué en convoquant la notion aristotélicienne d’oikos comme une transposition de la métaphore de « foyer », broyant de ce fait la frontière entre « dedans » et « dehors ».
La naturbanité, une utopie réalisée par le Parc national urbain de Stockholm ?
Authors: Girault Camille
Published: February 2022

Au prisme du Parc national urbain de Stockholm, un renversement des logiques de protection est ici envisagé comme figure de l’utopie : l’urbain n’est pas appréhendé comme une menace vis-à-vis de la nature, l’urbanité est au contraire considérée comme l’objet même de la protection. En se revendiquant comme la première ville du monde à avoir établi un tel « Parc national urbain », Stockholm nourrit l’image d’une cité idéale par l’établissement d’un espace urbain innovant. Ce dernier participe à l’identité urbaine et contribue à la production d’un rapport nordique au monde où des valeurs a priori contradictoires sont condensées en un même lieu. L’imbrication forte entre l’urbanité et la naturalité qui en résulte invite ainsi à proposer et à discuter la notion de naturbanité comme le fondement et l’expression d’une utopie réalisée dans la métropole suédoise.
Hybrid Model of Genetic Algorithms and Tabu Search Memory for Nurse Scheduling Systems
Authors: Abayomi-Alli Adebayo A. , Uzedu Frances Omoyemen , Misra Sanjay , Abayomi-Alli Olusola O. , Arogundade Oluwasefunmi T.
Published: February 2022

The main challenge of Nurse Scheduling Problem (NSP)is designing a nurse schedule that satisfies nurses preferences at minimal cost of violating the soft constraints. This makes the NSP an NP-hard problem with no perfect solution yet. In this study, two meta-heuristics procedures: Genetic Algorithm (GA) and Tabu Search (TS) memory was applied for the development of an automatic hospital nurse scheduling system (GATS_NSS). The data collected from the nursing services unit of a Federal Medical Centre (FMC) in Nigeria with 151 nursing staffs was preprocessed and adopted for training the GATS_NSS. The system was implemented in Java for Selection, Evaluation and Genetic Operators (Crossover and Mutation) of GA alongside the memory properties of TS. Nurses’ shift and ward allocation was optimized based on defined constraints of the case study hospital and the results obtained showed that GAT_NSS returned an average accuracy of 94%, 99% allocation rate, 0% duplication, 0.5% clash and an average improvement in the computing time of 94% over the manual approach.
On Modelling Process Aspects With Deontic Event-Calculus
Authors: Hashmi Mustafa
Published: February 2022

Intuitive and faithful modelling the compliance requirements about the process aspects is a prerequisite for their automated compliance checking. Several formalisms with varying degrees of expressiveness for modelling compliance requirements have been reported in the literature. Deontic Event-Calculus (DEC) is a normative variant of Event-Calculus (EC) formalism with predicates to modelled normative requirements. However, currently, DEC does not support capturing normative requirements about the process aspects. In this paper, we extend DEC with new deontic predicates to model process aspects of data, time, control flow, and resources. The extended deontic predicates enable DEC to intuitively represent the compliance requirements relevant to aspects of a business process. Besides, we report the complexity evaluation of the extended deontic predicates using well-known Halstead’s complexity metrics. Evaluation result demonstrates that the complexity of modelling the compliance rules with DEC predicates is significantly lower even when the complexity of the standard EC is exponential.
A Study of the Motivation of Collaborative Consumption and the Moderating Effect of Perceived Social Distance
Authors: Choi Youngkeun
Published: February 2022

The purpose of the present study was to examine the relationships between motivation factors and collaborative consumption engagement and explore the moderating effect of perceived social distance on that relationship. For this, the present study collected data from 228 college students in South Korean through a survey method. In the results, first, the more enjoyment or reputation participants perceive in collaborative consumption platforms, the more they are engaged in collaborative consumption. Second, a positive relationship between perceived enjoyment and collaborative consumption engagement is stronger for participants in collaborative consumption platforms high rather than low in perceived social distance. However, the perceived social distance was found to have no significance in the relationship between perceived reputation and collaborative consumption engagement.
Cardiogenic Shock and the Use of Percutaneous Mechanical Assist Devices
Authors: Simko Lynn Coletta
Published: February 2022

Percutaneous mechanical assist devices are used in patients with cardiogenic shock. The purpose of this article is to familiarize critical care nurses with the various types of percutaneous mechanical assist devices, including the intra-aortic balloon pump, the Impella device, extracorporeal membrane oxygenation, and the TandemHeart device. Each type of device requires specific nursing care. In a patient with cardiogenic shock, the monitoring, care, and interventions provided by an experienced critical care nurse can make the difference between survival and death.
Single Nucleotide Polymorphisms in Runt-related Transcription Factor 2 and Bone Morphogenetic Protein 2 Impact on Their Maxillary and Mandibular Gene Expression in Different Craniofacial Patterns - A Comparative Study
Authors: Olsson Bernardo , da Silva Mateus José , Lago Camila , Calixto Robson Diego , Ramazzotto Lucas Alexandre , Barbosa Rebellato Nelson Luis , Kirschneck Christian , Garcia Paula-Silva Francisco Wanderley , Küchler Erika Calvano , Scariot Rafaela
Published: February 2022

Introduction:

This study aimed to evaluate if single nucleotide polymorphisms (SNPs) in runt-related transcription factor 2 (RUNX2) and bone morphogenetic protein 2 (BMP2) are associated with different craniofacial patterns. Furthermore, we also investigated if RUNX2 and BMP2 expression in the maxilla and mandible are differently expressed according to facial phenotypes and influenced by the SNPs in their encoding genes. Orthognathic patients were included.

Materials and Methods:

Lateral cephalometric radiographs were used to classify facial phenotypes based on Steiner's ANB and Ricketts’ NBa-PtGn angles. Bone samples from 21 patients collected during orthognathic surgery were used for the gene expression assays. DNA from 129 patients was used for genotyping the SNPs rs59983488 and rs1200425 in RUNX2 and rs235768 and rs1005464 in BMP2. The established alpha was 5%.

Results:

A statistically significant difference was observed in the relative BMP2 expression in the mandible between Class I and III participants (P = 0.042). Homozygous GG (rs59983488) had higher RUNX2 expression (P = 0.036) in the mandible. In maxilla, GG (rs1200425) had a higher BMP2 expression (P = 0.038).

Discussion:

In conclusion, BMP2 is expressed differently in the mandible of Class I and Class III participants. Genetic polymorphisms in RUNX2 and BMP2 are associated with their relative gene expression.
The Usefulness of a Facial Digital Biobank for Ameloblastoma Resection and Fracture Fixation - A Case Report
Authors: Candido Isabella Romão , da Silva Carolina Silvano Vilarinho , Santos Garcia Eduardo dos , da Silva André Luís Fernandes , Fernandes Poleti Thais Maria Freire , Gialain Ivan Onone , Borba Alexandre Meireles
Published: February 2022

Rationale:

Ameloblastoma often requires complex facial treatments such as resection and reconstruction, which can be aided using three-dimensional resources towards improved surgical planning, reduction of surgical time, and customization.

Patient Concerns:

A 51-year-old patient, concerned about submandibular volumetric increase discovered performing imaging exams to install dental implants.

Diagnosis and Treatment:

Diagnosed with ameloblastoma, he underwent uneventful partial mandibular resection and placement of prebent mandibular reconstruction plate. Four months later, following a motorcycle accident, a deflection of the plate and mandibular fracture was observed. Using the initial prototyping, a new reconstruction plate was customized and surgically placed to reduce the mandibular fracture, with adequate titanium plate adaptation to the remaining bone and maintenance of aesthetic mandibular contour.

Outcomes and Take-away Lessons:

The current digital dentistry resources, such as computed tomography and intraoral scan, can be recovered and used as a backup of recorded anatomy anytime in future, providing a long-lasting facial digital biobank.
Surgical repair of umbilical hernia in a patient with Churg–Strauss syndrome under regional anaesthesia
Authors: Jonnavithula Nirmala , Veronica J. , Prathyusha Apparasu Chaitanya , Mathsya Giri
Published: February 2022

Churg–Strauss syndrome (CSS), also referred to as eosinophilic granulomatosis with polyangiitis, is characterised by asthma, peripheral and tissue eosinophilia, extravascular granuloma formation and vasculitis of multiple organ systems. Patients with CSS have higher risk for hyper-reactive airway disease. Administering general anaesthesia in such patients may be deleterious as it requires airway manipulation, use of muscle relaxants some of which are associated with release of histamine and use of anti-cholinesterases which can cause bradycardia, increased secretions and bronchial hyper-reactivity. We report a case of a 36-year-old male with known CSS presented with umbilical hernia for mesh repair which was managed with regional anaesthesia.
Statistical methods in clinical studies
Authors: Sarma K. V. S. , Mohan Alladi , Vedururu Sai Sarada
Published: February 2022

Basic knowledge of statistics is essential for the proper design of clinical studies, data handling methods, appropriate use of analytical tools and the interpretation of the findings. Recognising the importance of the need for competence in biostatistics and research methodology, the Medical Council of India has made it mandatory for the postgraduate medical student to learn research methodology by taking up an online course; and has also made it necessary for faculty in medical colleges to complete the online basic course in biomedical research to get promoted This review focusses on providing an overview regarding various statistical tools commonly used in the design of studies and analysis of data.
The Newman–Shapiro problem
Authors: Belov Yurii , Borichev Alexander
Published: February 2022

We give a negative answer to the Newman–Shapiro problem on weighted approximation for entire functions formulated in 1966 and motivated by the theory of operators on the Fock space. There exists a function in the Fock space such that its exponential multiples do not approximate some entire multiples in the space. Furthermore, we establish several positive results under different restrictions on the function in question.
Multi-level Governance in Centralized State? Evidence from China after the Territorial Reforms
Authors: Liao Liao , Shi Chunyu
Published: February 2022

China has long been considered a centralized country. Over the last 30 years, several reforms have gradually transferred important powers to local levels, particularly counties. The article analyzes this evolution based on a field study in two provinces, Zhejiang and Sichuan. The hypothesis is that the transfer of initiatives has become a new way of ‘steering’ counties’ identities in China. This article is based on an analysis from two perspectives. The first is an institutional perspective concerning financial, administrative, and political reform in China; the second is a neo-institutional perspective that examines counties’ identities and the role county-level actors play in territorial development and intergovernmental relations within their provinces.
Mitigação de riscos na validação da veracidade de cadastros compartilhados pelas instituições financeiras e o processo de análise dos indícios de lavagem de dinheiro
Authors: Fernandes Alessandro , Zani João
Published: February 2022

Uma das mais eficientes estratégias de combate ao crime organizado é o follow the money, uma vez que o dinheiro é a alma de qualquer organização criminosa e cabe às instituições financeiras o papel de notificar autoridades públicas sempre que tomarem conhecimento de operações suspeitas. Estes setores são caracterizados com gatekeepers, em função de o Brasil adotar um sistema de colaboração compulsória entre o setor público e o privado, em que profissionais e entidades que trabalham em setores mais usados por criminosos para ocultação de recursos devem notificar autoridades públicas sempre que tomarem conhecimento de operações suspeitas. O sistema bancário tem vivido grande impacto do crescimento da mobilidade e convergência digital, com o crescente uso de aparelhos celulares (smartphones) como canais bancários, impondo às instituições financeiras um novo desafio, uma vez que o "know your customer" diz respeito a uma das atividades mais difíceis de fazer online: certificar-se de que a pessoa do outro lado da rede é realmente quem ela diz ser. Porém ao possibilitar o compartilhamento de cadastros entre as instituições impõem a elas um novo desafio, uma vez que estas disrupções exigiram uma maior complexidade dos regulamentos atuais, uma vez que justamente por sua contemporaneidade, aumenta a dificuldade de precisar os riscos relacionais, dificultando a missão de criação e aplicação de normas antilavagem. Desta forma cabe a hipótese que move este estudo: como mitigar o risco do tratamento de dados compartilhados sem prejudicar o processo de "Know your customer". O presente trabalho, em função de seus objetivos, conduziu-se como uma pesquisa de revisão bibliográfica de natureza qualitativa, buscando a identificação dos riscos e sua mitigação, através da confecção de matriz de risco e aplicação do método 5W2H. Percebe-se após conclusão dos estudos que as instituições deverão manter suas políticas atuais de controle, tratando os dados de terceiros como dados complementares, sem abdicar dos cuidados hoje vigentes e adotando medidas adicionais no tratamento dos dados necessários para validação de sua veracidade.
Programa Nacional de Alimentação Escolar sob monitoramento
Authors: Cunha Beatriz
Published: February 2022

O artigo tem por objetivo analisar, criticamente, o Programa Nacional de Alimentação Escolar, incluindo a sua implementação, execução e sistemas de monitoramento. Assim, de início, faz-se uma breve apresentação do programa. Em seguida, enumeram-se as suas metas e sistemas de monitoramento. Após, são expostos os resultados de pesquisa que pretendeu avaliar como vem ocorrendo a execução dessa política pública no plano concreto, apontando eventuais incompatibilidades com o planejamento previsto. Para tanto, são divulgados os investimentos feitos em termos de recursos humanos e financeiros. Ato contínuo, adotando-se um compromisso com a realidade, são relatados os serviços que vêm sendo, efetivamente, prestados nos planos nacional, regional e estadual. Depois, o trabalho analisa criticamente se o resultado prático pretendido quando do planejamento da política está sendo alcançado. Por fim, conclui-se que as metas do Programa Nacional de Alimentação Escolar não estão sendo alcançadas em sua integralidade e os sistemas de monitoramento tendem a se restringir a controlar os recursos investidos e os serviços prestados, sem se preocupar, efetivamente, com o resultado final pretendido – o crescimento biopsicossocial dos alunos –, o que seria fundamental para que o direito fundamental fosse levado a sério.
Balance of digital transformation of the healthcare system on the example of vertically integrated medical information systems (VIMIS)
Authors: Boyarskikh A. V. , Efremov S. A. , Kavlashvili O. V. , Gryaznov I. M.
Published: February 2022

The change in demographic trends observed in most of the subjects of the Russian Federation in recent years has had an impact on the structure of morbidity. The increase in the morbidity of the population for certain classes of diseases required operational accounting and planning of increasing the corresponding health resources, procurement of medicines. National medical research centers are of fundamental importance in the management of the quality of medical care and the assessment of health resources. The lack of an effective control tool at national medical research centers for many years did not allow to increase the effectiveness of quality management of medical care. In 2019, the Ministry of Health of the Russian Federation created a modern mechanism for managing medical care in the main profiles throughthe use of vertically integrated medical information systems.The introduction of such information systems led to a search for a balance of interests of medical professionals who do not have the opportunity to spend a lot of time filling out various electronic documents and forms, as well as the interest of developers of information systems whose rigid algorithms had to be transformed into convenient and familiar business processes for doctors.The optimal solution proposed by the authors of this article is the use of regional specialized subsystems for disease profiles, which receive primary information about the case of treatment from various sources and automatically generate structured electronic medical documents.
Determinanten der coronabezogenen Schutzbereitschaft bei Jugendlichen und jungen Erwachsenen in Deutschland
Authors: Rossmann Constanze , Reinhardt Anne , Weber, Winja
Published: February 2022

Insbesondere bei Jugendlichen und jungen Erwachsenen wurde bereits 2020 eine zunehmende Pandemiemüdigkeit beobachtet, die sich in einer geringeren Motivation äußerte, empfohlene Maßnahmen zum Schutz vor COVID-19 einzuhalten. Eine theorie- und evidenzbasierte Kommunikationsstrategie ist daher unerlässlich, um die Schutzbereitschaft effektiv zu steigern. Entsprechend wurde zunächst ein theoretisches Modell zur Erklärung des Schutzverhaltens junger Menschen entwickelt und dieses in zwei aufeinander aufbauenden Befragungsstudien empirisch geprüft, um auf dieser Basis verhaltenswirksame Botschaftsinhalte und geeignete Kommunikationskanäle zu identifizieren. Der vorliegende Beitrag stellt zunächst die theoretische Basis vor, um anschließend die empirischen Befunde zu skizzieren und daraus Handlungsempfehlungen für eine Kommunikationsstrategie abzuleiten.
PREDICCIÓN DE LA SITUACIÓN ACADÉMICA EN ALUMNOS DE PREGRADO USANDO ALGORITMOS DE MACHINE LEARNING.
Authors: Gamboa Unsihuay Jesús Eduardo , Salinas Flores Jesús Walter
Published: February 2022

El rendimiento académico de un estudiante universitario generalmente se mide a través de sus calificaciones, las cuales derivan en una situación académica normal o deficiente, que a su vez depende de diversos factores. El objetivo de esta investigación fue encontrar los principales predictores de la situación académica de un estudiante universitario luego de que transcurrieron seis semestres desde su ingreso. Para el análisis de datos, se hizo uso del algoritmo Boruta para seleccionar variables predictoras y se aplicaron doce algoritmos de clasificación, previa partición de los datos en conjuntos de entrenamiento y evaluación. Luego, se eligieron aquellos modelos con mejores valores de sensibilidad, especificidad y balanced accuracy. Finalmente, se empleó un ensamble y un punto de corte óptimo para mejorar las predicciones. Los modelos con mejor desempeño fueron el de regresión logística, Naive Bayes y máquinas de soporte vectorial con kernel lineal. Al aplicar el ensamble con punto de corte óptimo se obtuvo especificidad de 0.695 y sensibilidad de 0.947. La nota obtenida en el curso de Matemáticas fue una de las más importantes para predecir la situación académica luego de seis semestres de estudios, mientras que las variables sociodemográficas no fueron relevantes.
DETERMINANTES GENÉTICOS Y SUS MECANISMOS DE ACCIÓN IMPLICADOS EN LA RESISTENCIA BACTERIANA A METALES PESADOS: UNA REVISIÓN.
Authors: Iza Guaman Joana Fernanda , Recalde Moreno Celso Guillermo , Iza Guaman Cristian Fabricio
Published: February 2022

Se identificó y describió los principales determinantes genéticos implicados en la resistencia bacteriana a metales pesados reportados en la literatura, así como sus usos a nivel biotecnológico y ambiental. Se llevó a cabo una revisión bibliográfica de información de los últimos 10 años encontrados en revistas con indexación SJR disponibles en las diferentes bases de datos; bosquejando la situación actual del conocimiento sobre el tema y realizando comparaciones cualitativas entre las investigaciones seleccionadas. Las bacterias se encuentran en constante evolución y se vuelven más resistentes gracias a la adquisición de genes que les permite hacer frente a los efectos tóxicos de los metales. Por ello, se compiló desde varios autores los determinantes genéticos de resistencia bacteriana para los metales, como el arsénico, mercurio, cromato y cadmio siendo respectivamente: ars, mer, chr, cad y czc; estos sistemas pueden localizarse en el cromosoma o plásmidos de las bacterias. Se describe el mecanismo de acción que codifica cada determinante, siendo la regulación y la desintoxicación enzimática los principales mecanismos. Finalmente, se comparó las aplicaciones biotecnológicas y ambientales de los determinantes, encontrándose un amplio uso en la construcción de biosensores y organismos genéticamente modificados.
Legal Analysis Regarding Ex-Convicts as Election Contestants Based on the Indonesian Constitutional Court Decision
Authors:   Master of Law, Faculty of Law, Universitas Diponegoro, Nirwanto Arystha
Published: February 2022

Ex-convicts must wait for a five-year gap after passing their prison term and announce their background if they want to run for governor, regent, or mayor, according to the Constitutional Court's decision Number 56/PUU-XVII/2019. The election of regional heads is an activity in the context of implementing a government system in the form of democracy. In the implementation of regional head elections, to get quality regional leaders, it takes qualified candidates promoted by political parties as well as those who run independently. Among the requirements for a regional head candidate, both at the provincial and district/city levels, a candidate must not be in a status of an ex-convict. The research method in this research was normative juridical. This research shows that based on the 1945 Constitution of the Republic of Indonesia, ex-convicts are also citizens who have the same political rights as other citizens. The existence of a provision that is a requirement to run as a candidate for the regional head in the election clearly limits or even negates a person's right to participate in exercising their rights. The decision of Constitutional Court No.42/PUU-XIII/2015 states that ex-convicts can participate in regional head elections with certain conditions.
Prevalencia de la enfermedad de Pompe entre pacientes con elevación de creatinin-kinasa (CK)
Authors: Marin J. , Scaglioni V. , Zacariaz J. , Vergara F. , Rosa J. , Soriano E.R.
Published: February 2022

Introducción: La prevalencia exacta de la enfermedad de Pompe en la población general es desconocida, y la frecuencia estimada varía entre las diferentes formas clínicas y grupos étnicos. Existe un gran número de pacientes con elevación de enzimas musculares que no tienen un diagnóstico definitivo. Un porcentaje de ese grupo de pacientes podría tener enfermedad de Pompe. Objetivos: 1) Determinar la prevalencia de la enfermedad de Pompe entre pacientes mayores de un año de edad, con elevación persistente de creatin-kinasa (CK) de causa desconocida. 2) Describir las manifestaciones clínicas y demográficas de los pacientes con CPK elevada. Materiales y métodos: Se incluyeron a todos los pacientes con aumento de CK en sangre, definida como la detección de al menos un valor >500 UI/L y otro mayor de 200 UI/L, durante un período mínimo de 1 año, entre los años 2010-2013, tomados de la base de datos del laboratorio del Hospital Italiano de Buenos Aires. Se excluyeron a los pacientes bajo tratamiento actual con agentes hipolipemiantes; pacientes tratados con agentes hipolipemiantes, en quienes la CK no se normalizó luego de suspender el tratamiento; pacientes tratados con agentes hipolipemiantes que interrumpieron el tratamiento durante un tiempo menor de 9 meses antes del período de inclusión y pacientes con enfermedad muscular inflamatoria (pacientes con criterios diagnósticos probables o definidos de Bohan & Peter). Los pacientes con diagnóstico probable de miositis por cuerpo de inclusión (biopsia no típica) podían ser incluidos. Se les realizó evaluación clínica (medición de la fuerza muscular), cuestionario sobre síntomas musculares y se les extrajo sangre para test enzimático en papel de filtro para enfermedad de Pompe. Resultados: Se revisaron 849 historias clínicas; 199 pacientes cumplieron con los criterios de inclusión de los que 110 pacientes fueron evaluados. Se pudo realizar el test enzimático en papel de filtro para diagnóstico de enfermedad de Pompe en 93 de los 110 pacientes evaluados. A 21 pacientes se les realizó electromiograma y a 10 pacientes biopsia muscular. Se pudo establecer el diagnóstico del aumento de la CK sólo en el 34,4% de los pacientes. El diagnóstico de enfermedad de Pompe se realizó en 1 paciente, mostrando una prevalencia del 1,07%. Conclusiones: La prevalencia de enfermedad de Pompe fue similar a la publicada en la literatura. Se pudo hacer el diagnóstico del aumento de CK elevada en un bajo porcentaje de pacientes (34,4%).
¿Es momento de adoptar el DAPSA para la evaluación de la Artritis Psoriásica?
Authors: Soriano Enrique R.
Published: February 2022

La mejor forma de evaluar la respuesta al tratamiento en artritis psoriásica no está aún definida. Importantes esfuerzos están siendo realizados por grupos como GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) y OMERACT (Outcome Measures in Rheumatology), para validar instrumentos para la medición de la actividad de esta enfermedad y para encontrar algún instrumento que evalúe la misma en forma global. Encontrar un solo instrumento que sea capaz de evaluar la enfermedad en sus principales y distintos dominios de compromiso (piel, articulaciones, compromiso axial, uñas, entesitis y dactilitis), es difícil, por la desconexión que muchas veces existe entre la actividad de los mismos.
¿Es la artrosis de la rodilla, por fricción (plica), una realidad? Análisis de esta patología degenerativa articular
Authors: Nieto-Andueza E. , Valenti-Nin J. R.
Published: February 2022

La osteoartrosis de rodilla es la causa más común de dolor en el adulto mayor, se trata de una afección secundaria a diferentes patologías y afecta todas las estructuras intraarticulares. Un posible factor etiológico podría ser secundario a una plica medial inﬂamada y engrosada. Esta modalidad de patología no ha sido considerada en ninguna de las clasiﬁcaciones existentes y puede ser diagnosticada previamente, en la mayoría de los casos, mediante una resonancia magnética y conﬁrmada por artroscopia. Los autores actualizan el tema y presentan un caso de artrosis del compartimiento medial de la rodilla secundaria a una plica medial.
49º Congreso Argentino de Reumatología
Authors: De Reumatología Sociedad Argentina
Published: February 2022

49º Congreso Argentino de Reumatología
Desempeño del RAPID3 en pacientes con osteoartritis de rodilla, cadera o mano
Authors: Kohan M.P. , Medina M.A. , Papasidero S.B. , Chaparro del Moral R. , Rillo O.L. , Caracciolo J.A.
Published: February 2022

RAPID3 es un cuestionario autorreportado desarrollado originalmente para valorar pacientes con AR. Recientemente fue empleado en pacientes con OA de rodillas y/o caderas con buenos resultados.Objetivo: Determinar si existe correlación entre el RAPID3 y otros cuestionarios en pacientes con OA de manos (AUSCAN), cadera y/o rodilla (WOMAC) y comparar el tiempo para su realización y cálculo.