bluuebunny/crossref_metadata_2025 huggingface dataset:
Kinetics of Left Ventricular Mechanics during Transition from Rest to Exercise
Authors: IZEM OMAR , MAUFRAIS CLAIRE , OBERT PHILIPPE , RUPP THOMAS , SCHUSTER IRIS , NOTTIN STÉPHANE
Published: April 2019

Purpose

At the onset of physical exercise, oxygen (O2) transport adapts to meet the working muscle O2 demands. Cardiac output abruptly increases through the concomitant changes of HR and stroke volume (SV), which is conditioned by the left ventricular (LV) function. The purpose of this study was to investigate the contribution of many LV diastolic and systolic function parameters, including twist–untwist mechanics, to SV adaptation during the first minutes after exercise onset.

Methods

Diastolic and systolic myocardial strains and twist were monitored by two-dimensional speckle-tracking echocardiography with high temporal resolution in 28 young men (mean age, 23 ± 4 yr) who performed five similar constant work-load exercises on a cycloergometer (target HR: 125 bpm). Two-dimensional cine-loops were recorded every 15 s during the first minute of exercise, and then every 30 s for the next 3 min.

Results

During the first 60 s of exercise, SV (from 104 ± 15 mL to 126 ± 21 mL, P < 0.001) increased concomitantly with LV strain and strain rates. Early filling was the main SV determinant during this phase, probably linked to the increase of venous return (at the very beginning of exercise), LV relaxation (from 1.5 ± 0.3 s to 2.5 ± 0.4 s, P < 0.001) and untwisting (from −78 ± 34°·s−1 to −165 ± 61°·s−1, P < 0.001). After the first minute, SV remained constant, whereas LV untwisting continued to increase (from −165 ± 61°·s−1 to −187 ± 60°·s−1, P < 0.001) and the other systolic and diastolic parameters reached a plateau.

Conclusions

This study gives new mechanical insights into LV kinetics to address the challenge of SV response at the onset of exercise.
Diagnóstico e tratamento de lesões não cariosas: a visão do cirurgião-dentista do sistema público de saúde
Authors: Ribeiro Vanessa Savastano de Cerqueira Rêgo , De Almeida Emanoel Lima , Leal Isabelly de Carvalho , Bizerril Davi Oliveira , Saintrain Maria Vieira de Lima , Ferreira Regina Glaucia Lucena Aguiar , Passos Vanara Florêncio
Published: April 2019

Introdução: as lesões dentárias não cariosas apresentam etiologia multifatorial e, caracterizam-se por ocasionar desgastes irreversíveis na estrutura dentária, sem envolvimento de microrganismos, podendo ser diagnosticadas como erosão (de origem intrínseca ou extrínseca), abfração, atrição ou abrasão. Objetivo: analisar o conhecimento de cirurgiões-dentistas a respeito do diagnóstico e do tratamento dos diferentes tipos de lesões dentárias não cariosas. Métodos: realizou-se estudo observacional, descritivo, de natureza quantitativa, utilizando-se, como instrumento de coleta de informações, um questionário semiestruturado aplicado em cirurgiões-dentistas do município de Fortaleza-CE. Os resultados foram analisados de forma descritiva e foi utilizado o teste de Qui-Quadrado com nível de significância de 5%. Resultados: verificaram-se, entre os cirurgiões-dentistas, os seguintes percentuais de acerto referentes às lesões de abfração, abrasão, atrição, erosão de origem extrínseca, erosão de origem intrínseca e erosão de origem extrínseca associada à abrasão, respectivamente: 51,97%, 20,60%, 78,43%, 81,37%, 71,57% e 7,84%. Observou-se, também, associação estatisticamente significante positiva entre o conhecimento dos profissionais a respeito de lesões de abfração e atrição e o tempo de formado. Conclusão: embora grande parte dos profissionais tenham sido capazes de identificar um plano de tratamento adequado para os casos propostos em questão, o diagnóstico das lesões não cariosas não foi preciso, exceto quando se tratou de erosão de origem intrínseca ou extrínseca e atrição que obtiveram percentual de acertos acima de 70%.
Ácido tânico como agente biomodificador de dentina
Authors: Mendes Talita Arrais Daniel , Pascoal Samuel Chillavert Dias , Lemos Marcelo Victor Sidou , Santiago Sérgio Lima , Mendonça Juliano Sartori
Published: April 2019

Introdução: a utilização de diferentes polifenóis no aumento das propriedades mecânicas do colágeno dentinário tem sido bastante empregada, sendo o ácido tânico um polifenol com propriedade biológica bastante pronunciada. Objetivo: o objetivo deste estudo é avaliar o potencial biomodificador do ácido tânico (AT) em diferentes concentrações em colágeno dentinário. Métodos: os fatores sob investigação foram módulo de elasticidade, mensurado por meio de um ensaio de flexão de três pontos (n=10) e variação de massa (n=10), aferidos com uma balança de precisão, sendo, para tanto, avaliados os seguintes elementos: ácido tânico (0,1; 1 e 10%), proantocianidina (6,5%) e água destilada (controle). Resultados: quanto ao módulo de elasticidade, os grupos tratados com ácido tânico apresentaram valores, estatisticamente, superiores (p<0,05) aos demais grupos, não sendo observadas diferenças entre suas diferentes concentrações. Para os valores de variação de massa, os grupos que foram imersos em agentes biomodificadores apresentaram valores estatisticamente (p<0,05) superiores ao grupo controle. Conclusão:  o ácido tânico se apresenta como um potencial agente biomodificador do colágeno dentinário, independente da concentração utilizada, aumentando o seu módulo de elasticidade e gerando um ganho de massa após uma hora de imersão.
Developing acceptable contraceptive methods: Mixed-method findings on preferred method characteristics from Burkina Faso and Uganda
Authors: Brunie Aurélie , Callahan Rebecca L. , Mackenzie Amelia , Kibira Simon P.S. , Wayack-Pambè Madeleine
Published: April 2019

Background: Unmet need remains high in developing regions. New contraceptive technologies may improve uptake and use. This study examines desirable product characteristics.

Methods: We added a module to the female questionnaire of the PMA2020 surveys in Burkina Faso and Uganda and conducted 50 focus group discussions (FGDs) with women, 10 FGDs with men, and 37 in-depth interviews (IDIs) with providers across the two countries. FGDs with women and IDIs with providers included a semi-structured ranking exercise on pre-selected product characteristics.

Results: Effectiveness, duration, few side effects, cost, and access were the characteristics most commonly reported as important in choosing a method by survey respondents across both countries. Half or more of women surveyed in each country would like a method that lasts at least one year, while 65% in Burkina Faso and 40% in Uganda said they would use a method causing amenorrhea. Qualitative findings show that women want methods with minimal and predictable side effects. Reactions to increased bleeding were negative, especially in Burkina Faso, but perspectives on reduced bleeding were more mixed. Women and providers preferred methods that are discreet and not user-dependent, and associate duration with convenience of use. Some women in Uganda expressed concerns about the invasive nature of long-acting methods, and cost was an important consideration in both countries. In the ranking exercise, discreet use and few side effects often ranked high, while causing amenorrhea and not requiring a pelvic exam often ranked low.

Conclusion: Product development should consider user preferences for success in these settings.
The Organization of Independent Work of Students in Conditions of Competence-Based Learning
Authors: Чиркова Н. , Chirkova N. , Павлова О. , Pavlova O.
Published: April 2019

The article reveals the essence of the competence approach to the organization of independent work of students at the University. The implementation of this model leads to an increase in the role and optimization of independent work as a leading component of professional training of the future specialist. The main directions of design and realization of independent work are allocated. The basic forms of the organization of independent activity of students are presented.
The Humanitarian Component of Mathematical Education As a Methodical Basis of Professional Development of Teachers of Mathematics
Authors: Лукичева Е. , Lukicheva E.
Published: April 2019

The article investigates the features of humanization and humanization of mathematical education. These characteristics are considered as a theoretical basis for advanced training of teachers of mathematics in the development of the modern system of school mathematics education. A deep analysis of the term “mathematics” in order to understanding and perception o the role and importance of mathematics teachers for the development of civilization, scientifi c and technological progress, as well as the universal language of any modern science is made. Specifi c examples of integration (as replenishment of knowledge) and interpenetration of the content of mathematics and other educational areas (physics, chemistry, Philology, philosophy, etc.), contributing to the quality of school education are given. The emergence of a new modern metamathematics is noted, which is extremely relevant in the process of achieving metasubject learning outcomes by students. Values, opportunities and necessity of development of the personality of the school student by means of the subject “mathematics” are discussed.
Theory and practice of expert methods
Authors: Коробов Владимир , Korobov Vladimir , Кочуров Борис , Kochurov Boris
Published: April 2019

The monograph addresses the issues of expert evaluation of complex systems. The survey techniques, the methods for calculating the weighting factors of influencing factors, the approaches to the formalization of the objects of study are described. The advantages and disadvantages of the procedures and algorithms used are analyzed. It is shown how expert estimates can be applied in various models and metrics. Examples of implementation in the tasks of territorial zoning, assessment of situations, and the selection of the most promising alternative are given.
The monograph is designed for researchers, graduate students and undergraduates and engineers of various specialties who use in their research and development methods of multi-criteria evaluation of complex systems.
Legal basis of the mechanism of implementation of the constitutional right to social security in the Russian Federation
Authors: Байматов Павел , Baymatov Pavel
Published: April 2019

The monograph is a study of theoretical and practical problems associated with the implementation of the constitutional right of citizens to social security. It adequately covers the historical and contemporary issues of the right to social security in Russia, studying international experience.
The book raises the problem of implementation of the constitutional right of citizens to social security in the Russian Federation in modern conditions, if necessary, reduce the paternalistic role of the state, proposed measures aimed at increasing the role of citizens, identified theses related to the search for the most optimal and effective forms of modernization of the mechanism of realization of the right to social security.
The book is addressed to state and municipal employees, deputies of representative bodies of state power and local self-government, researchers, teachers, graduate students, students of Humanities and a wide range of readers.
Economics of educational institution
Authors: Захарчук Лариса , Zaharchuk Larisa
Published: April 2019

The key concepts of the course, economic problems of educational institutions in the conditions of the modern financial mechanism and modernization of the education system of the Russian Federation are revealed. The practical significance of the manual gives the presence of applications, which include the curriculum for the course, the subject of abstracts, examples of problem-situation problems and final control for students.
The manual is addressed to students and teachers of teacher training colleges, universities, and will be useful for students of the system of professional development and retraining of teachers.
Robust Dual Sourcing Inventory Management: Optimality of Capped Dual Index Policies and Smoothing
Authors: Sun Jiankun , Van Mieghem Jan A.
Published: April 2019

Problem definition: How to dynamically replenish inventory from two supply sources or shipping modes with general lead times. The fast source is more expensive than the slow source. Academic/practical relevance: Dual sourcing provides supply chain flexibility to mitigate demand and supply risk. Despite its relevance in practice, characterizing the optimal dual sourcing policy is extremely challenging, and the optimal stochastic policy for nonconsecutive lead times has been unknown for over 50 years. Methodology: We present and solve a robust rolling horizon model for periodically reviewed dual sourcing inventory systems that minimizes the total cost of purchasing, inventory holding, and backlogging. Results: We prove that the optimal robust policy is a dual-index, dual-base-stock policy that constrains or “caps” the slow order and provide closed-form expressions for the three control parameters. The optimality result is established for general lead times and can accommodate nonstationary demand. Our numerical study shows that, as the lead time difference grows, the capped dual index policy increasingly smooths slow orders and for stationary demand, converges to the tailored base-surge policy, which places a constant slow order and has been shown to be asymptotically optimal. Managerial implications: Our capped dual index policy is easy to understand, explain, and implement in practice. In an extensive simulation study, the capped dual index policy performs as well as and can even outperform the best heuristics presented in the stochastic inventory literature.
Results of Bronchoscopic Lung Volume Reduction with One-way Valve in Patients with Severe Emphysema in Vietnam
Authors: Ba T Ta , Khac H Dong , Q Do , Ngoc B Dao , Huy L Nguyen , Viet N Nguyen
Published: April 2019

Background: Bronchoscopic lung volume reduction (BLVR) has been applied in COPD patients with heterogeneous emphysema. In this first clinical trial in Vietnam, we evaluated the safety and initial results of BLVR by one-way valve in COPD patients with severe emphysema. Methods: We performed a prospective, nonrandomized, single center longitudinal study in 30 stable COPD patients with heterogeneous severe emphysema on CT-scanner, the average age of 65.17 years old, FEV1≤35 %pred., TLC ≥ 100 %pred., RV ≥ 150 %pred. and 6MWT < 450 meters. The Zephyr one-way bronchial valves (PulmonX, Redwood City, CA, USA) with the size of 5.5 mm and 4mm were placed in lobar or segmental bronchi via flexible bronchoscopy. 28 patients were placed only one valve, 1 patient with two and 1 patient with three valves. 23 valves with the size 5.5 mm diameters and 10 valves with the size 4.0mm used. All patients received optimal medical treatment at the time of procedure and during the study period. Outcomes will be assessed at 3 months after treatment include the changes of clinic, and lung function, the occurrence of complications. Results: After 3 months, mean CAT scores decreased significantly compared with before procedure (17.73 ± 3.53 vs 20.10 ± 3.58) (p<0.05), with the median change of 2.73 points and the improvement more than 2 points in 76.67% of patients. 6 MWT increased at 3 months with mean 32.13 meters, 93.33% of the patients increased 6MWT, 46.67% of the patients increased 6MWT more than 26 meters. MRC decreased with the median change of 0.5 score. VC decreased by a mean 0.2 (L) (0.42 - 0.02), FEV1 increased by a mean 0.05 (L) (0.04 - 0.05) but not statistically significant (p>0.05); FVC increased by a mean 0.14 (L) (0.01 - 0.28), RV decreased by a mean 0.62 (L) (1.05 - 0.2), TLC decreased by a mean 0.52 (L) (0.77- 2.4) with statistically significant (P<0.05). The early complications were 13.33%, the later complications were 23.34% of the patients. Conclusions: The unilateral bronchoscopic lung volume reduction with one-way valve (mainly one valve) in treatment of heterogeneous severe emphysema in stable COPD patients in Viet Nam have shown that this procedure is safe with encouraging initial results.
Lung Cancer and Isolated Adrenal Metastases: Different Disease?
Authors: Sardenberg Rodrigo A. S. , Younes Riad N. , Costa Marcos André , Teixeira Carlos Henrique A.
Published: April 2019

Distant metastases generally indicate disseminated disease and the standard treatment for these patients is palliative chemotherapy. Retrospective series showed that selected patients with metastatic lung cancer and a solitary extrathoracic disease could be effectively treated with curative intention by resection of both primary tumor and the single site of metastatic disease.

According to current data, adrenalectomy might be considered as an alternative option for patients with isolated adrenal metastases. Significant morbidity and mortality may be happened by these procedures, and a cautious analysis of pros and cons should be discussed with the patient.

We present a review of the literature and updated recommendations focusing lung cancer with solitary adrenal metastasis.
Diaphragmatic Pacing as an Alternative to Mechanical Ventilation: Early Experience from a Developing Country
Authors: Sardenberg Rodrigo A. S. , Younes Riad N
Published: April 2019

Background The aim of this study is to evaluate the outcomes of patients submitted to diaphragmatic pacing, and the impact on quality of life of patients who chronically depend on mechanical ventilation, as well as the effectiveness of phrenic stimulation to eliminate the need for mechanical ventilation. Methods From 2010- 2014, 10 patients completely dependent on mechanical ventilation were operated upon, with the implantation of phrenic pacing device. The diagnoses were quadriplegia and congenital central hypoventilation syndrome (CCHS). All patients underwent bilateral approach to the phrenic nerves, by video-assisted thoracic surgery or mini-thoracotomy. Results All patientsstarted pacing 30-40 days post-operatively. The mean age of patients was 12.1 years (2-27 years range) with a median of ten years. Six patients (54.5%) were as old as ten years, and three (27.2%) were older than 20 years. Younger patients had CCHS and older ones were quadriplegic. All patients with CCHS (n = 4) were nine years old or younger while only two quadriplegic patients were in this age group. Conclusions Diaphragmatic pacing can provide improvement in the quality of life of patients who depend on mechanical ventilation, allowing freedom to conduct daily activities, lower respiratory infections, and tracheostomy decannulation.
Análisis Espacial de Vecindad Continua y regresión logística en el modelado espacial de probabilidad de ocurrencia de deslizamientos
Authors: Castro Miguel Rutilio , Legorreta Paulín Gabriel
Published: April 2019

Este trabajo presenta un análisis comparativo de dos modelos estadísticos de probabilidad de procesos gravitacionales (PG) aplicando regresión logística (RL), utilizando la variable pendiente del terreno. En un primer modelo se analizó información in situ de sitios con deslizamientos y áreas estables; en el segundo, se analizó la información de los mismos sitios utilizando Análisis Espacial de Vecindad Continua (AEVC). La precisión que reportaron ambos modelos (in situ y AEVC), se evaluó estadísticamente con la medida de ajuste de -2 Logaritmo de la Verosimilitud (-2LL).Para la calibración de los modelos se utilizó un inventario de deslizamientos y el Continuo de Elevación Mexicano versión 3.0 (CEM 3.0) del Instituto Nacional de Estadística y Geografía (INEGI).Los resultados muestran que utilizando la información de las áreas de vecindad se obtiene un mayor nivel de ajuste de la ecuación en comparación con el modelo elaborado utilizando la información in situ.El valor de -2LL para el modelo con datos de vecindad fue de 264.312 y para los datos in situ fue de 269.573. Del mismo modo, la tabla de clasificación global del modelo de vecindad reportó un 58.5 %, mientras que para el análisis in situ fue de 51.8 %, lo anterior muestra un aumento de la correcta clasificación en el modelo estadístico del 6.7 % al utilizar el análisis de vecindad.El área de estudio es la cuenca del río La Ciénega, ubicada en la ladera este del volcán Nevado de Toluca, en el Estado de México.
Tiers et objetcivité sociale chez Georg Simmel
Authors: Lits Grégoire
Published: April 2019

La notion de tiers apparaît dans différents textes de Georg Simmel. Sans être systématiquement conceptualisée par l’auteur, elle permet de comprendre la vision du monde social qui sous-tend la sociologie qu’il propose. A partir de l’analyse de deux chapitres de Sociologies, nous pourrons montrer que la société pour Simmel ne se réduit pas à une somme d’interactions mais possède des aspects extérieurs – holistes – rassemblant les individus. Dans une seconde partie la notion de tiers est examinée quant à son intérêt pour l’étude des sociétés contemporaines mondialisées en établissant, à partir des travaux de Vincent Descombes sur les significations partagées, une différenciation entre deux types de tiers sociaux.
El orden social en Colombia. Una interpretación
Authors: Salazar Silva Fernando
Published: April 2019

Este artículo ofrece una interpretación austriaca acerca de la pérdida de la naturaleza social del individuo y su implicación en la configuración del orden social en Colombia. En la concepción mecánica el orden solo es entendido como una entelequia, lo cual significa que a sus constitutivos se les despoja de sus experiencias y costumbres, propiciando la presencia de un planificador que de manera artificial da vida a los individuos y los pueda ordenar. Este punto es relevante para comprender la dificultad en la imposición de límites a la arrogancia gubernamental.
Furthering regional energy security instead of national approaches
Authors: Dos Santos Thauan
Published: April 2019

This paper argues that furthering energy security should move beyond a national approach and consequently consider a regional one. The case study considers Mercosur and UNASUR, covering the period between 2015-2050. The methodology is based on energy modeling and scenarization using the Open Source Energy Modelling System – South America Model Base (OSeMOSYS-SAMBA), a model of planning for the expansion of long-term energy systems. The modeling exercise supports the argument that greater electricity integration in Mercosur (and in South America as a whole) promotes a reduction in the need to increase installed capacity, as well as lower geographic and socio-environmental impacts.
Pengaruh Pajanan Gas Hidrogen Sulfida (H2S) terhadap Keluhan Saluran Pernafasan pada Pemulung di Tempat Pembuangan Akhir (TPA) Ganet Kota Tanjungpinang Tahun 2018
Authors: Simbolon Veronika Amelia , Nurmaini Nurmaini , Hasan Wirsal
Published: April 2019

Latar belakang : Hidrogen Sulfida (H2S) merupakan gas yang tidak mudah terbakar, tidak berwarna dan berbau seperti telur busuk dan masuk ke tubuh manusia terutama melalui udara yang dihirup. Paparan konsentrasi rendah Hidrogen Sulfida (H2S) dapat menyebabkan iritasi pada mata, hidung, atau tenggorokan. Penelitian ini bertujuan untuk mengetahui pengaruh pajanan gas Hidrogen Sulfida (H2S) terhadap keluhan saluran pernafasan pada pemulung, di TPA Ganet Kota Tanjungpinang.Metode : Jenis penelitian ini adalah survei bersifat analitik deskriptif  dengan desain cross sectional. Sampel dalam penelitian ini yaitu pemulung yang pekerjaannya hanya sebagai pemulung dengan lama bekerja ≥ 3 tahun  dan durasi terpapar  ≥ 40 jam/minggu dengan jumlah sampel memenuhi syarat 27 pemulung.Hasil : Berdasarkan uji statistik dengan Fisher,s Exact Test diketahui ada pengaruh jenis kelamin (p = 0,019 PR = 1,9) dan intake (p = 0,039 PR = 2,1) terhadap keluhan saluran pernafasan. Variabel yang paling berpengaruh dominan pada uji regresi logistik antara jenis kelamin, konsentrasi H2S dan intake terhadap keluhan saluran pernafasan pada pemulung di TPA Ganet Tahun 2018 yaitu jenis kelamin dan intake dengan probabilitas 97,9 %.Simpulan : Ada pengaruh yang signifikan antara jenis kelamin dan intake dengan keluhan saluran pernafasan pada pemulung di TPA Ganet Kota Tanjungpinang. ABSTRACTTitle: The Effect of Exposure Hydrogen Sulfide Gas (H2S) on the Complaints of Respiratory Track in Scavengers at the Ganet’s Final Waste Disposal of Tanjungpinang 2018Background : Hydrogen Sulfide (H2S) is a gas that is not flammable, colorless and smells like rotten eggs and enters the human body primarily through inhaled air. Exposure on low concentrations of Hydrogen Sulfide (H2S) can cause irritation to the eyes, nose or throat. This study aims to determine the effect of exposure to Hydrogen Sulfide (H2S) gas the respiratory tract complaints in scavengers at the Ganet’s final waste disposal of Tanjungpinang.Methods : This type of research is a descriptive analytic survey with a cross sectional design. The samples in this study were scavengers whose works were only as scavengers with length of work ≥ 3 years and duration of exposure ≥ 40 hours / week with the number of samples fulfilling the requirements of 27 scavengers.Results : Based on the statistical test with Fisher,s Exact Test it is  found that there was influence of sex (p = 0.019 PR = 1.9) and intake (p = 0.039 PR = 2.1) on respiratory complaints. The most dominant variable influenced the logistic regression test between gender, H2S concentration and intake of respiratory tract complaints on scavengers in 2018 TPA Ganet, were gender and intakes with a probability of 97.9%.Conclusion : There is a significant influence between gender and intake with complaints of respiratory tract on scavengers in TPA Ganet, Tanjungpinang City.
Early Childhood Caries
Authors: Seminario Ana Lucía , Ivančaková Romana
Published: April 2019

Early childhood caries (ECC) represents a serious problem in pediatric dentistry. Not only because of its rapidity but also because of age of affected children. This has been given different names such as “rampant caries” and “baby bottle syndrome” but now all clinical manifestations have been joined and classified as early childhood caries. The topic of this article is the prevalence, etiology, clinical manifestations and preventive measures of ECC.
The Repair of DNA Damage Induced in Human Peripheral Lymphocytes with Styrene Oxide
Authors: Köhlerová Renata , Štětina Rudolf
Published: April 2019

Isolated human peripheral lymphocytes were treated in vitro with styrene-7, 8–oxide (SO) and the kinetics of the repair of induced DNA damage was assessed by comet assay during further incubation of lymphocytes. Using a modified assay we measured simultaneously the number of single strand breaks in DNA (SSBs) and the sites sensitive to endonuclease III (endo III) that most probably represent abasic sites in DNA molecules. SO induced DNA damage in a dose–dependent manner and both SSBs and endo III sites were removed from the DNA by a repair process with a half time about 2–4 hours. The damage was repaired completely within 12 hours after the treatment.
Intravascular Large B-Cell Lymphoma Presenting As Cutaneous Panniculitis
Authors: Dědič Karel , Belada David , Žák Pavel , Nožička Zdeněk
Published: April 2019

In this report the case of intravascular large B-cell lymphoma (angiotropic lymphoma, intravascular angioendotheliomatosis, malignant endotheliomatosis) with panniculitis features is present. The diagnosis was based on finding of typical CD20 positive tumorous cells within capillaries, veins, and small arteries in the biopsy of subcutaneous adipose tissue. An accurate and early diagnosis together with combined chemotherapy resulted in good response and remission of the disease.
Effects of process conditions on the heat transfer coefficient at the polymer-mold interface and tensile strength of thin-wall injection molding parts
Authors: Zhu Laiyu , Min Liping , Li Xianglin , Zhai Zhanyu , Drummer Dietmar , Jiang Bingyan
Published: April 2019

Generally, the strength at the weld line of the injection molded part is very weak. The heat transfer coefficient (HTC) between the polymer melt and the mold cavity surface was analyzed to solve this problem. The surface roughness of the mold cavity and the material of the mold insert were changed to adjust the interface environment between the polymer melt and the mold cavity surface. HTC was obtained by combing the experimental measurement with the theoretical calculation. In the current study, the influence of HTC on the tensile strength of the weld line of the molded specimen was investigated. The results show that the weld line strength of the molded specimen increases with the decrease in HTC between the polymer and the mold cavity surface. Meanwhile, the decrease in the surface roughness of the mold cavity or replacing the mold material with lower thermal conductivity can reduce the value of the HTC between the polymer and the mold effectively and can delay the cooling rate of the hot polymer melt. This provides a new idea to solve thin-wall injection molding weld line defects.
Synthesis of porous resorcinol-formaldehyde resins and study of their sorption characteristics toward Cs in highly mineralized alkaline media
Authors: Egorin Andrei , Tokar Eduard , Palamarchuk Marina , Portnyagin Arseniy , Tutov Mikhail , Mis’ko Daria , Kalashnikova Anastasia , Sokolnitskaya Tatiana , Tananaev Ivan
Published: April 2019

The present work was devoted to study of sorption parameters of resorcinol-formaldehyde resins synthesized through introduction of an inorganic filler (in amounts of 10 and 25 wt.%) with its subsequent leaching. The surface morphology and composition of ion-exchange resins have been investigated by means of the method of scanning electron microscopy. The effect of internal diffusion on the peculiarities of the ion-exchange process has been determined. It has been revealed that the ion-exchangers destruction upon a prolonged contact with highly alkaline solutions is followed by the decrease of internal diffusion coefficients and selectivity toward Cs-137 micro-quantities. The sorption properties of resins under dynamic conditions at high solution feeding rates have been studied. A sample with the highest efficiency of Cs-137 removal from highly mineralized solutions has been identified.
Zur Autonomie indirekter Redewiedergabe – Eine diachrone Perspektive
Authors: Demske Ulrike
Published: April 2019

Regarding verbal mood and complementation patterns of reporting verbs, the distinction between direct and indirect reported speech is well established in present-day German. This paper looks into the history of German: Common knowledge has it that both the use of verbal mood as well as the quality of clause linkage undergo considerable changes giving rise to the question how these changes affect the manifestations of indirect reported speech in earlier stages of German. The historical record of the 16th century (with an outlook on the 17th century) shows that the distinction between direct and indirect reported speech is not yet grammaticalized in historical sources at the time. In particular with respect to dependent (in)direct reported speech, both types prefer V2-complements with only verbal mood differentiating between the types. Although present and past subjunctive have a much wider distribution in earlier stages of German, the occurrence of free indirect speech likewise testifies to its increasing use as a marker of indirect reported speech. The growing conventionalization of patterns of indirect reported speech in the course of Early Modern German may be considered as an example for an increase of subjectification in its development.
Redewiedergabe – Schritte zur automatischen Erkennung
Authors: Brunner Annelen
Published: April 2019

This contribution presents a quantitative approach to speech, thought and writing representation (ST&WR) and steps towards its automatic detection. Automatic detection is necessary for studying ST&WR in a large number of texts and thus identifying developments in form and usage over time and in different types of texts. The contribution summarizes results of a pilot study: First, it describes the manual annotation of a corpus of short narrative texts in relation to linguistic descriptions of ST&WR. Then, two different techniques of automatic detection – a rule-based and a machine learning approach – are described and compared. Evaluation of the results shows success with automatic detection, especially for direct and indirect ST&WR.
Humulus japonicus stimulates thermogenesis and ameliorates oxidative stress in mouse adipocytes
Authors: Jung Tae Woo , Kim Hyoung-Chun , Shin Yong Kyoo , Min Hyeyoung , Cho Seong-Wan , Kim Zi Soo , Han Su Mi , Abd El-Aty A M , Hacımüftüoğlu Ahmet , Jeong Ji Hoon
Published: April 2019

An aqueous extract ofHumulus japonicus(AH) has been documented to ameliorate hypertension and non-alcoholic fatty liver disease (NAFLD). Here, we investigated the effects of an aqueous extract of AH on thermogenesis and palmitate-induced oxidative stress in adipocytes. To verify the effect of AH on browning, we measured the expression levels of specific markers in 3T3-L1 adipocytes using qPCR and Western blotting, respectively. To assess the role of oxidative stress, cells were stained with DCFDA and observed by fluorescence microscopy. AH increased the expression of brown adipose tissue-specific markers. Additionally, it induced fatty acid oxidation and lipolysis and suppressed both lipogenic markers and lipid accumulation. Furthermore, AH ameliorated hydrogen peroxide-induced oxidative stress. Enhanced expression of these markers contributed to fat browning, fatty acid oxidation and lipolysis of 3T3-L1 adipocytesviathe AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor delta (PPARδ) signaling pathways. Moreover, AMPK and PPARδ resulting in protective effects of AH against oxidative stress. In sum, AH could promote the browning, lipolysis and thermogenesis in 3T3-L1 adipocytes and would suppress the hydrogen peroxide-induced oxidative stress and lipogenesis during differentiation. We therefore suggest that AH could be used as a potential candidate for treating obesity and related metabolic disorders.
Conductive Characteristics of Thin-Film Composite Materials with Mineral Fillers
Authors: Domantsevich N. I. , Yatsyshyn B. P.
Published: April 2019

The investigation of conductive characteristics and surface structure of polyethylene films modified by fillers was carried out. The dependence of changes in surface and volume resistivity on the quantity of non-metallic filler and time-based changes in structure and electrophysical characteristics for three years has been established.
Investigation of structural, electrokinetic and energy state properties of the semiconductive Zr1-xVxNiSn solid solution
Authors: Romaka V. , Romaka L. , Stadnyk Y. , Horyn A. , Krayovskyy V. , Romaniv I. , Garanuyk P.
Published: April 2019

Structural, electrokinetic and energy state characteristics of the Zr1-xVxNiSn semiconductive solid solution (х=0–0.10) were investigated in the temperature interval 80–400 К. It was shown that doping of the ZrNiSn compound by V atoms (rV=0.134 nm) due to substitution of Zr (rZr=0.160 nm) results in increase of lattice parameter а(х) of Zr1-xVxNiSn indicating unforecast structural change. Based on analysis of the motion rate of the Fermi level ΔεF/Δх for Zr1-xVxNiSn in direction of the conduction band it was concluded about simultaneous generation of the structural defects of the donor and acceptor nature (donor-acceptor pairs) by unknown mechanism and creation of the corresponding energy levels in the band gap of the semiconductor.
Specific Features of Photoconductivity of Tl1-xIn1-xSnxSe2 Monocrystals at Low Temperatures
Authors: Novosad O.V. , Myronchuk G.L. , Danylchuk S.P. , Zamurueva O.V. , Piskach L.V. , Kityk I.V. , Piasecki M.V. , Tsisar O.V.
Published: April 2019

The photoconductivity spectra in the temperature range T≈36-200 K and the spectra of thermostimulated currents in the temperature range T≈70-300 K of Tl1-xIn1-xSnxSe2 single crystals obtained by directional crystallization of Bridgman-Stockbarger have been studied. The induced photoconductivity and long-term photoconductivity relaxation processes have been found. To interpret the found results, a model of two-center recombination has been suggested. It is illustrated that the role of the r-centers of slow recombination are formed by Tl vacancies. On the basis of the studies of the spectra of thermally stimulated currents, the thermal energy of electrons activation with t-levels of adhesion has been determined.
Aging Processes in Films of Iron-Yttrium Garnet Implanted by Boron Ions
Authors: Yaremiy I. P. , Povkh M.M. , Kotsyubynsky V.O. , Fedoriv V.D. , Yaremiy S.I. , Pashkovska R.I.
Published: April 2019

Based on the results of X-ray structural analysis, changes in the crystalline structure that occurred during 15 years in surface layers of epitaxial films of iron-yttrium garnet implanted by B+ ions were studied. The processes that occur during the B+ ion implantation of in ferrite-garnet films, and the processes that accompany the low-temperature aging of ion-implanted films are considered. Strain profiles were determined from the experimental rocking curves, obtained immediately after ion implantation and after 15 years. It was found that the value of relative maximum deformation of surface layers decreases at constant thickness of the disturbed layer.
Conciencia colectiva: del estructuralismo marxista al biopragmatismo
Authors: Rodríguez Ortiz Angélica María
Published: April 2019

Las teorías contemporáneas sobre la conciencia colectiva se enfocan desde dos extremos opuestos: estructuralismo y emergentismo. El estructuralismo marxista centra su definición de conciencia colectiva desde el externalismo; teorías que someten la conciencia individual a la construcción social, que termina por someter el “yo” al “nosotros”. De otra parte, el emergentismo searleano propone hablar de una intencionalidad y una conciencia colectiva del “nosotros” en la mente de cada individuo, cuya ontología es biológica. Una propuesta naturalista que permite reconocer la conciencia colectiva del “nosotros” en armonía con la conciencia del “yo”, pues ambas están en la mente de cada individuo, es decir, se apuesta por una teoría internalista de la conciencia, que a la postre resulta insuficiente, puesto que los fundamentos ontológicos desde la biología no dan cuenta per se de la intencionalidad que tiene un colectivo. Por ello, se propone al lenguaje y la acción como elementos determinantes para comprender la ontología de la conciencia colectiva. Una apuesta por una visión biopragmática de la conciencia colectiva, que retoma los elementos básicos del emergentismo searleno y propone como condiciones de posibilidad elementos como el lenguaje y acción, los cuales permiten hablar de estados mentales en la colectividad.
CAX and Xsel: a software bundle to aid in automating NAA spectrum analysis
Authors: Zahn Guilherme Soares , Junqueira Lucas Stano , Genezini Frederico Antonio
Published: April 2019

In this work, the scripting capabilities of Genie-2000 were used to develop a software (CAX) that automatically analyses all spectrum files in either Ortec's CHN or Canberra's MCA or CNF formats in a folder, generating two output files: a print-ready text file (.DAT) and a Comma-Separated Values (.CSV) file which can be easily imported in any major spreadsheet software. A second tool, named Xsel, consists in an Excel spreadsheet which automatically identifies the spectrum lines associated with the elements of interest, generating a clean output sheet which can be easily imported in a general spreadsheet that calculates the concentrations; an important addition to this spreadsheet is the ability to automatically recalibrate each spectrum, increasing the reliability of the peak identification procedure. These software are already used in daily routines in IPEN's Neutron Activation Laboratory, greatly reducing the time required for sample analyses, as well as reducing the possibility of transcription errors.
Indonesia and Two Great Narratives on Islamic Studies
Authors: Hidayat Komaruddin , Darmadi Dadi
Published: April 2019

There are at least two interesting facts about Indonesia and the Muslim world. First, Indonesia is the largest Muslim country in the world. With more than 260 million people, Indonesia is the 4th most populous country in the world, and here Islam is the most adhered to religion. With approximately 87 % of its population are Muslims, the largest Muslim population in one country lives in Indonesia.Second, a large number of Muslim majority countries are not Arabs. According to the Pew Research Center, approximately 20 percent of Muslims live in Arab countries. Turkey and Iran, two non-Arab countries, are the largest Muslim-majority countries in the Middle East. Meanwhile, South Asia and Southeast Asia cover around 62 percent of the world’s Muslims. Indonesia alone is home to 12.7 percent of all world’s Muslims.These two facts show Indonesia’s unique position in the Islamic world. On the one hand, Indonesia is one of the farthest countries from the Arab World, but Islam that comes from there has been deeply rooted in the daily lives of many Indonesian Muslims. On the other hand, Indonesia which was colonized for more than three hundred years by Western colonialism, did not take for granted the influence of Arab cultures, and even more in contact with modernity, both directly and indirectly introduced by way of colonialism.
Home Oxygen and 2-Year Outcomes of Preterm Infants With Bronchopulmonary Dysplasia
Authors: DeMauro Sara B. , Jensen Erik A. , Bann Carla M. , Bell Edward F. , Hibbs Anna Maria , Hintz Susan R. , Lorch Scott A.
Published: April 2019

OBJECTIVES:

To compare medical and developmental outcomes over the first 2 years of life in extremely preterm infants with bronchopulmonary dysplasia (BPD) who were discharged on supplemental oxygen via nasal cannula with outcomes of infants with a similar severity of respiratory illness who were discharged breathing in room air.

METHODS:

We performed a propensity score–matched cohort study. Eligible infants were born at <27 weeks’ gestation, were receiving supplemental oxygen or respiratory support at 36 weeks’ postmenstrual age, and were assessed at 18 to 26 months’ corrected age. Study outcomes included growth, resource use, and neurodevelopment between discharge and follow-up. Outcomes were compared by using multivariable models adjusted for center and age at follow-up.

RESULTS:

A total of 1039 infants discharged on supplemental oxygen were propensity score matched 1:1 to infants discharged breathing in room air. Infants on oxygen had a marginal improvement in weight z score (adjusted mean difference 0.11; 95% confidence interval [CI] 0.00 to 0.22), with a significantly improved weight-for-length z score (adjusted mean difference 0.13; 95% CI 0.06 to 0.20) at 22 to 26 months’ corrected age. Infants on oxygen were more likely to be rehospitalized for respiratory illness (adjusted relative risk 1.33; 95% CI 1.16 to 1.53) and more likely to use respiratory medications and equipment. Rates of neurodevelopmental impairment were similar between the groups.

CONCLUSIONS:

In this matched cohort of infants with BPD, postdischarge oxygen was associated with marginally improved growth and increased resource use but no difference in neurodevelopmental outcomes. Ongoing and future trials are critical to assess the efficacy and safety of postdischarge supplemental oxygen for infants with BPD.
ON SEMINAR CLASSES IN THE DISCIPLINE “HISTORY OF PEDAGOGY AND BULGARIAN EDUCATION” AT THE FACULTY OF EDUCATION, TRAKIA UNIVERSITY, STARA ZAGORA
Authors: Apostolova Delcheva Tzveta
Published: April 2019

The article analyzes the organization of the seminar classes in the discipline "History of Pedagogy and Bulgarian Education" at the Faculty of Education, Trakia University, Stara Zagora. It describes the mechanism for the selection of appropriate interactive techniques and methods for the seminar classes, which is required by the changed profile of today’s student, as well as the profile of a group of students in a given specialty. A working model for group work in "History of Pedagogy and Bulgarian Education" is presented.
BUILDING BASIC VISUAL PERCEPTIONS OF STUDENTS OF PEDAGOGY UNPREPARED FOR COMMUNICATING WITH VISUAL ARTS
Authors: Tineva-Gyurkovska Katya , Zlateva Ani
Published: April 2019

This research contains certain pedagogical problems concerning the basic visual perceptions of the students from the pre-school and primary school education specialty at the Faculty of Education in Trakya University, reviewed on theoretical and analytical level. People studying to become primary school teachers are expected to teach the subject Art in their future pedagogical carrier, but they are often unprepared for communicating with the visual arts. They don't have former knowledge in this area. That is why the aims of this article are connected to presenting the real "picture" of their level of perception when in touch with pieces of art in a museum environment. The stages of understanding, perceiving and free usage of the Art terminology are being tracked. 
Two aspects are concerned in theoretical plan: Ideas of some of the greatest Art theoreticians concerning the stages of development of the visual perceptions, viewed from artistic, psychological and pedagogical point of view. How students can assimilate and apply them in direct communication with visual arts. The article marks the meaning, role and place of Art galleries and museums in the pedagogical process of future and current teachers and art pedagogues. 
On empirical level this article systematizes the problems connected with the methodology of Fine Arts education, and more specifically with this part, related to the application of their knowledge of theory, art history and interpretation of pieces of art. Based on this pedagogical analysis the article makes some important conclusions for the level of competence and abilities to assimilate objects connected to the visual arts.
The importance of institutional trust for financial service providers among young adults and their parents in an emerging market
Authors: Zsótér Boglárka , Bauer András
Published: April 2019

Trust in financial institutions can be seen as a foundation for loyalty and profits in the banking industry and is relevant for the macro economy as well. Young customers are more likely to lack trust due to their lack of personal experience in finance, although parental advice may lower their risk. In this paper the authors combine trust measures with intergenerational communication theory and test it on a large dyadic sample using Z-scores. The results show a strong, holistic intergenerational effect on institutional trust, but shed light on heterogeneity in the sample due to gender, financial independence and different communication styles.