bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetik Belirteçler ve Hayvan Yetiştiriciliğinde Uygulamaları
Authors: Üstün Muhammed Furkan , Koyun Hasan
Published: December 2024

DNA dizilimlerinde genetik polimorfizmlerin keşfedilmesi, hayvanlarda gözlemlenen fenotipik varyasyonu açıklamak için yeni araçlar sunmuştur. Belirli lokuslarda allelik varyasyonun ortaya koyulması, bu çeşitliliğin anlaşılması amacıyla genetik belirteçler kullanılması yaygın hale gelmektedir. Bu da, çiftlik hayvanlarındaki genetik çeşitliliğin değerlendirilmesine, ebeveyn kontrolüne ve hastalık vektörlerinin belirlenmesinin yanında ekonomik öneme sahip özelliklerde rol oynayan önemli gen ve/veya genlerin tanımlanmasına (QTL ve MAS) olanak sağlamıştır. Bu çalışmada, son yıllarda hayvansal üretimde yaygın olarak kullanılan genetik belirteçlerin belirlenmesinde kullanılan yaygın yöntemlere (AFLP, RAPD, RFLP, SSCP, mikrosatellit işaretleyiciler, STR ve SNP) yer verilmiş ve uygulama alanları değerlendirilmiştir.
Comparison of Chemical, Nutritional and Fatty Acid Composition of Organic and Conventional Milk Manufactured in Türkiye
Authors: Büyükkılıç Beyzi Selma
Published: December 2024

Due to its polyunsaturated fatty acids (PUFA) and conjugated linoleic acid (CLA), milk plays a significant role in human nutrition. The purpose of this study was to ascertain the fatty acid composition of milk samples that were both conventional and organic. The commercial milk products were bought from several shops in the Türkiye city of Kayseri. From various retail establishments in the city, three different brands and three different lots within a brand were acquired. The t-test was used to assess the data. C14:0, C16:0, C18:0, and C18:1 fatty acids were the main ones found in milk. Organic milk showed a higher PUFA, but also lower levels of monounsaturated fatty acids (MUFA) and higher levels of saturated fatty acids (SFA). There was no difference between conventional and organic milk CLA concentration. Excess cholesterol in the diet has been increasingly acknowledged to cause atherosclerosis in recent years. As a result, dairy products with low cholesterol are more popular and advised. This study measured the fat and cholesterol content of conventional and organic milks. The percentage of milk fat in the conventional and organic samples was 3.34% and 2.73%, respectively. Organic and conventional milk had cholesterol ratios of 207.1 and 452.0 mg/100 g, respectively. The conventional and organic milk samples had 4% fat-corrected cholesterol concentrations of 303.5 and 541.28 mg/100g, respectively. Consequently, organic milk had a decreased cholesterol level (P
ENDÜSTRİYEL ŞARTLARDA ÜRETİLMİŞ TİCARİ BULYONLARIN CİS-TRANS YAĞ ASİTLERİ İÇERİĞİ VE GIDA GÜVENLİĞİ AÇISINDAN ÖNEMİ
Authors: Dıraman Harun
Published: December 2024

Bir bulyon (küp veya tablet olarak), kurutulmuş bitkilerden alınan lezzet artırıcı bir ürün olarak, kırmızı et/ tavuk et suyu ile küçük bir miktarda kısmi hidrojene yağ ve tuz - bazen MSG (Mono Sodyum Glutamat) - içeren bir üründür ve Dünya ve Türk mutfaklarında genellikle lezzet arttırıcı olarak kullanılmaktadır. Bu makalede, dünyada ve Türkiye’de çeşitli hayvansal ve bitkisel katkıları içeren ticari/endüstriyel bulyonların cis - trans yağ asidi profilleri üzerine gerçekleştirilen bilimsel çalışmalar dikkate alınmıştır. Bu amaçla çalışmada, bulyon üretiminde trans yağ asitleri içen hidrojene yağ kullanımı, trans yağ asitlerinin oluşumu ve trans yağ asitleri sağlık ilişkisi, bulyon üretimi hakkında genel bilgiler ve margarin ve/veya bulyonlarda cis – trans yağ asidi profili üzerine yapılan bilimsel çalışmalar alt başlıklar halinde açıklanmıştır. Trans yağ asitleri (TFA), trans konfigürasyonunda en az bir konjuge olmayan çift bağ içeren doymamış yağ asitleridir. Beslenmedeki toplam TFA, endüstriyel olarak (kısmi hidrojene bitkisel yağlardan) üretilen bulyon vb ürünler ve ruminantlardan doğal olarak (biyohidrojenizasyon) elde edilen (süt ve et) ürünlerden kaynaklanabilir. Makalede bu konu, bulyonların cis yağ asidi profiline göre iyot sayısının hesaplanması ve muhtemel hayvansal (özellikle domuz ürünleri) katkıların mevcudiyetinin tahmin edilmesi ve helal statüsü açısından da ele alınmıştır. Sonuç olarak, bu madde ile birlikte Türkiye'de üretilen bulyon ambalajları üzerinde "Trans Yağ Asidi İçerir/Trans Yağ Asidi Sıfır" ibaresinin yer almasının toplum sağlığı, sağlıklı beslenme ve gıda güvenliği açısından gerekliliği gündeme getirilmiştir.
KAVUŞMAK ÜZERE SALIVERİLEN İKİ DENİZİN KADİM HİKAYESİ: İLAHİ ATIFLAR VE BİLİMSEL GERÇEKLER
Authors: Öztürk İzzet
Published: December 2024

Son buzul çağı öncesi bir tatlı su gölü olan Karadeniz’in Marmara ve Türk Boğazlar Sistemi üzerinden Akdeniz ile birleşmesi günümüzden takriben 7500 yıl öncesine tarihlendirilmektedir. Bu çalışmada, günü-müzden ~3000 yıl önce mevcut halini aldığı tahmin edilen bu eşsiz doğa olayının; jeolojik, oşinografik, hidrolojik, ekolojik ve hidrodinamik özellikleri, güncel bilimsel bulgular ışığında ele alınmıştır. Bu kapsamda çalışmada, öncelikle sözü edilen birleşme olayının tarihi ve jeolojik evrimi incelenmiştir. Daha sonra Karadeniz, Marmara ve Türk Boğazları ile Kuzey Ege Denizi’ni kapsayan bütünleşik bir 3 boyutlu Hidrodinamik Model (Delft 3D Modeli) yapılandırılarak anılan sistemin güncel oşinografik, ekolojik ve hidrodinamik özellikleri ortaya konulmuştur. En son aşamada ise İstanbul içinden altlı üstlü (üsten güneye doğru az tuzlu Karadeniz, alttan kuzeye doğru çok tuzlu Akdeniz) akmakta olan bu iki deniz arasında yaşanan benzersiz doğa olayı ile ilgili olarak Kuran’ı Kerim’de günümüzden 14 asır önce yapılan mucizevi atıflar değerlendirilmiştir. Bu bağlamda özellikle Rahman Suresi’nin 19 ila 22. ayetlerinde yapılan atıfların, tam anlamıyla Türk Boğazlar Sistemi ve Marmara Denizini işaret ettiği anlaşılmaktadır. Sonuçta bu durumun da etik bir problem olarak değerlendirilmesi kaçınılmazdır. Şöyle ki, bilimsel ilgi ve merakın bilim literatürü ile birlikte felsefi ve dini metinleri de kapsaması gerektiği; bilimsel görünme adına Kuran-ı Kerim başta olmak üzere, gerektiğinde dini metinlere atıf yapılmaktan kaçınılmasının etik sorunlar içerdiği düşünülmektedir.
Complications of electrosurgery: mechanisms and prevention strategies
Authors: El-Sayed S.M. , Saridogan E , El-Sayed M.M.
Published: December 2024

Background: Electrosurgery is widely used in all surgical specialities. There is evidence that surgeons in different disciplines and with different experience levels have an inadequate understanding of the basics of electrosurgery and its complications. This can increase the risk of electrosurgical complications. Despite its improved safety technology, electrosurgery is still associated with serious morbidity and mortality. In addition, such adverse outcomes will incur financial losses to our health system due to the costs of repeated operations, prolonged hospital stays, and litigation.

Objectives: To identify the various mechanisms of electrosurgical complications and to highlight the recommended actions to prevent such complications.

Materials and Methods: Narrative review based on a literature search of the Medline database using the following search terms: “electrosurgery”, “complications”, “risks”, and “adverse effects”, with further citation searching for related articles.

Main Outcome Measures and Results: The paper does not address specific research questions but addresses common knowledge gaps in the mechanisms of electrosurgical complications among surgeons.

Conclusions: Electrosurgical devices can cause severe complications such as unintended tissue burns, surgical fires, smoke hazards, and interference with implantable devices. Although such energy devices are designed with increasingly improving safety features, an adequate understanding of the circumstances, mechanisms, and prevention of these complications by the surgical team is the cornerstone in mitigating such risks.
Visual-Numeric Endometriosis Scoring System (VNESS) for mapping surgical findings: A validation study
Authors: Khazali S , Mondelli B , Fleischer K , Bachi A , Adamczyk M , Lemos N , Krentel H , Vashisht A , Abdalla A , Mohazzab A , Delanerolle G , Possover M , Padmehr R , Shadjoo K , Moawad G , Lee T , Saridogan E
Published: December 2024

Background: Several endometriosis classification systems have been proposed and published but the search for a universal language that communicates the complexity, laterality and severity of this disease continues. The authors introduce the Visual-Numeric Endometriosis Scoring System. VNESS is a novel system for describing surgical findings in each compartment of the pelvis in a way that is simple to use, visually intuitive and mirrors a laparoscopic image of the pelvis.

Objective: The aim of this study was to assess inter-rater reliability for components of VNESS.

Materials and Methods: The project took the format of a validation study using short surgical laparoscopic video clips. Anonymised video clips of endometriosis procedures were scored by 50 Gynaecologists of varying levels of experience from 12 different countries. The clips were collated from a series of procedures performed between 2012 and 2022. Each participant scored 93 short surgical clips using VNESS. 4650 scores were compared against a reference score and analysis was performed to assess inter-rater reliability.

Main outcome measures: The outcome measures were percentage agreement between given and reference scores, as well as intra-class correlation coefficients (ICC), Cohen Kappa and Quadratic Weighted Kappa Coefficients calculated to evaluate inter-rater reliability.

Results: The highest and lowest percentage agreement with the reference score was seen in VNESS 4 (full thickness disease, 97% perfect agreement) and VNESS 1 (superficial disease, 53% perfect agreement) respectively. The intraclass correlation coefficient showed strong inter-rater reliability for all VNESS compartments except the vagina.

Conclusions: This study suggests that VNESS has excellent reliability between observers. Correlation is stronger with more severe disease.
Perspectivas atribuídas às relações entre corpo, saúde e lazer por professores(as) universitários(as) de Educação Física ao longo da trajetória docente
Authors: De Souza Gomes Roberta , Cavalcanti Novaes Renato , De Cassio Costa Telles Silvio , Camargo Silva Alan
Published: December 2024

O objetivo do presente estudo foi analisar e compreender como os(as) professores(as) universitários(as) de Educação Física de uma instituição pública de ensino relacionam as noções de corpo, saúde e lazer, isto é, diante da trajetória profissional. A partir de uma abordagem qualitativa, foram realizadas onze entrevistas semiestruturadas com oito professores e três professo ras, na faixa etária entre 40 e 64 anos, graduados(as) entre 1970 e 1990. Identificou-se como o “se exercitar” e o comer ficam en tremeados à sobrecarga laboral dos docentes e como tentam articular os comportamentos individuais ao contexto de trabalho na universidade.
Grain size analysis of deposits in a debris flood area – Damdere River, Eastern Rhodopes, Bulgaria
Authors: Rizova Radostina , Nikolova Valentina
Published: December 2024

Debris flows and debris floods are a natural hazard that commonly occurs in mountainous regions. They can cause significant damage to infrastructure and pose serious threats to safety. Historical occurrences of debris flows can be identified through the deposits they leave behind. Studying these deposits offers valuable insights into these destructive events and supports improving prevention strategies’ development. In this regard, the study article is focused on the grain size analysis of the deposits of temporary flow by sieve/aerometric method. The obtained results confirm the torrential character of the river.
Trace elements of unbound residual copper in ancient metallurgical slags from the archaeological open-pit mine in the Propadnala Voda deposit, SЕ Bulgaria
Authors: Tzankova Nikoleta
Published: December 2024

This study presents, for the first time, trace element data obtained through LA-ICP-MS for unbound residual copper found as unextracted drops (or prills) in metallurgical slags from an open-pit mine located in the Propadnala Voda deposit within the Rossen Ore Field in the Burgas ore district. The analysis reveals the following chemical elements in amounts above the sensitivity limits of the equipment: Sc – 307 ppm, Cr – 52633 ppm, Ni – 670 ppm, Ag – 418 ppm, La – 15 ppm, Ce – 33 ppm, Ta – 17 ppm, Pb – 602 ppm, and Bi – 109 ppm. Since the ore source for the copper production, from which these slags are a byproduct, has been identified, the obtained data can be used to establish correlations with trace elements in metal artifacts searching for the ore-metal relationship. Additionally, the results of this study, which include determined ore melting temperatures, can enhance our understanding of the advancements in smelting technology during that period and the characteristics of the furnaces used.
ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ ВЛИЯНИЯ РЕЖИМА ГОРЯЧЕЙ ПРОДОЛЬНОЙ ПРОКАТКИ НА СТРУКТУРУ, ТЕКСТУРУ И СВОЙСТВА ДВУХФАЗНОГО ТИТАНОВОГО СПЛАВА ВТ14
Authors: Логинов Ю.Н. , Илларионов А.Г. , Водолазский Ф.В. , Шварц Д.Л. , Постыляков А.Ю. , Карабаналов М.С. , Посохин А.А.
Published: December 2024

В статье проведен анализ влияния режима горячей прокатки на формоизменение, структурно-текстурное состояние и свойства титанового сплава ВТ14. Определен фазовый состав, текстура и морфология образующихся фаз в исходном состоянии и после прокатки по различным маршрутам. Показано влияние степени деформации между проходами на формирование различных компонент текстуры деформации и рекристаллизации. Проанализированы зависимости уширения при плющении от относительного обжатия при горячей деформации сплава ВТ14 в проходе. Отмечено уменьшение коэффициента уширения при близкой степени деформации с увеличением номера прохода. Определена взаимосвязь между влиянием исследованных режимов горячей деформации на соотношение количества α/β-фаз, дисперсность вторичной α-фазы в структуре, развитие процессов рекристаллизации в β-фазе и фиксируемым в сплаве ВТ14 уровнем твердости и контактного модуля упругости.

The article analyzed the influence of hot rolling on the shape change, structure and texture and properties of the titanium Ti–4,5Al–3Mo–V (VT-14) alloy. The phase composition, texture and morphology of the phases in the initial state and after rolling were determined. The influence of the degree of deformation between passes on the formation of various components of the deformation texture and recrystallization is shown. The dependences of spreading during flattening during hot deformation of the VT14 alloy in a pass are analyzed. A decrease in the spread ratio at a similar degree of deformation was noted. The relationships between the hot deformation routes, the α/β phase ratio, the morphology of the secondary α phase, the development of recrystallization in the β-phase, and the hardness and contact elasticity modulus of the VT14 alloy were determined.
ТЕРМИЧЕСКИЙ АНАЛИЗ МЕХАНОАКТИВИРОВАННОЙ СМЕСИ Cr–B
Authors: Приписнов О.Н. , Шелехов Е.В. , Рупасов С.И.
Published: December 2024

Смесь хром–бор атомного состава CrB2 была подвергнута механоактивации в высокоэнергетической планетарной мельнице в течение 6–40 мин при соотношении шары : материал, равном 20:1. Молотые порошки были исследованы рентгеновской дифракцией и другими методиками. Затем смесь нагревали в установке с начальной скоростью ~6 оС/с до температуры 1000 оС. На кривых нагрева наблюдались экзотермические пики, связанные с образованием боридов. Температура начала этого превращения снижалась со временем помола до 15 мин и далее выходила на плато. Это связано с образованием тонкой слоистой структуры при росте продолжительности помола и с достижением предела утонения структуры. Оптимальное время помола для подготовки шихты к самораспространяющемуся высокотемпературному синтезу должно составлять 15–20 мин, так как утонение слоев рулета после этого практически прекращается или становится очень медленным. При такой продолжительности помола боридообразования в барабане не происходит, то есть энергетический заряд смеси не расходуется. Вместе с тем, имеются литературные данные, что при помоле продолжительностью 40 ч до 50% бора переходит в CrB2.

A chromium-boron mixture with composition corresponding to CrB2 boride was subjected to mechanical activation in a high-energy planetary mill for 6–40 minutes at a balls to material ratio of 20:1. The milled powders were studied by X-ray diffraction and other methods. Then the mixture was heated in a unit with an initial speed of ~ 6°C/s to a temperature of 1000°C. Exothermic peaks associated with the formation of borides were observed in the heat flow curves. The temperature of the transformation initiation dropped with grinding time to 15 minutes and then reached a plateau. This is due to the formation of a thin layered structure as the milling duration increases and the limit of its thinning is reached. The optimal milling duration for preparing the mixture for self-propagating high-temperature synthesis should be 15–20 minutes, since the thinning of the roll layers after this practically stops or becomes very slow. At such milling duration, boride formation does not occur in the grinder, that is, the energy of the mixture is not consumed. At the same time, there is literature data indicating that during milling for 40 hours, up to 50% of the boron is converted into CrB2.
СТРУКТУРА И СВОЙСТВА ДИФФУЗИОННЫХ ПОКРЫТИЙ СИСТЕМЫ Al–Ti–Cu
Authors: Шморгун В.Г. , Слаутин О.В. , Кулевич В.П. , Новиков Р.Е.
Published: December 2024

Показано, что термическая обработка по режиму 700 °С, 2 ч + 910 °С, 1 ч сваренного взрывом композита медь М1 + титан ВТ1-0 + алюминий АД1 с толщинами слоев, обеспечивающими реализацию «сквозной» диффузии, позволяет получать на поверхности меди покрытие твердостью 4–6,5 ГПа. Его основными структурными составляющими являются твердые растворы на основе купридов титана (Ti3Cu4, TiCu2, TiCu4) и эвтектика TiCu2+TiCu4, а поверхностный слой состоит из смеси фаз TiAl3 + CuTi2Al5 и двухфазной прослойки CuTi2Al5 + Al4Cu9. Структура покрытия свободна от дефектов кристаллизационного характера. В сравнении с бинарными покрытиями на основе интерметаллидов βTiCu4 и TiCu2 его износостойкость в 1,5 раза выше.

It has been shown that heat treatment at 700 °C, 2 h + 910 °C, 1 h of an explosively welded composite M1 copper + VT1-0 titanium + AD1 aluminum with layer thicknesses that ensure the implementation of “through” diffusion allows one to obtain a coating of hardness 4-6.5 GPa on the copper surface. Its main structural components are solid solutions based on titanium cuprides (Ti3Cu4, TiCu2, TiCu4) and eutectic TiCu2+TiCu4, and the surface layer consists of a mixture of TiAl3 + CuTi2Al5 phases and a two-phase interlayer CuTi2Al5 + Al4Cu9. The coating structure is free from crystallization defects. In comparison with binary coatings based on intermetallic compounds βTiCu4 and TiCu2, its wear resistance is 1.5 times higher.
Romantic Relationship Stability of University Students: The Role of Attachment and Self-Change
Authors: Özsolak Ayşegül , Tuzgöl-Dost Meliha , Kızıldağ-Şahin Seval
Published: December 2024

This study examined whether attachment and self-change predict relationship stability and whether relationship stability differs according to gender. The research data consisted of 403 participants, both online and face-to-face. Multiple linear regression analysis was conducted to determine the predictive power of self-change and attachment on relationship stability in university students. Independent samples t-test was conducted to determine whether there was a difference in the relationship stability levels of the participants according to gender. According to the findings obtained from the analysis, university students' self-expansion, self-contraction, anxious attachment, and avoidant attachment levels significantly predict relationship satisfaction. Self-expansion, self-adulteration, self-contraction, and anxious attachment significantly predict the level of evaluation of the quality of options. Self-expansion, self-contraction, self-adulteration, anxious attachment, and avoidant attachment significantly predicted relationship investment, whereas self-expansion, self-contraction, self-adulteration, and avoidant attachment significantly predicted commitment. In addition, men's relationship satisfaction and relationship investment levels are significantly higher than women's. The findings were discussed and interpreted in line with the literature on relationship stability, and some suggestions were presented for researchers and practitioners.
THE RESULTS OF COMPLEX THERAPY OF HEMOBLASTOSES WITH COVID-19: SINGLE-CENTER EXPERIENCE AT THE CVI-1 DEPARTMENT OF THE NATIONAL RESEARCH ONCOLOGY CENTER (ASTANA, KAZAKHSTAN)
Authors: VILDANOVA R. , MUKAZHANOV A. , KEMAYKIN V. , KARABEKOV A. , SAPARBAY J. , KHAMITOVA Z. , KUANYSH Z.
Published: December 2024

Relevance: The SARS-Cov2 pandemia caused an unparalleled health crisis that directly affected the course and treatment of patients with hemoblastosis. Hematologists faced an extraordinarily challenging situation due to the administered chemotherapy along with the treatment of the concomitant infectious pathology of coronavirus infection (CVI). However, there were no clear recommendations and approved protocols for diagnosis and treatment for this category of patients for the described period. Patients with hematological malignancies are generally more susceptible to infections due to immunosuppression caused by their disease and the deteriorating effect of treatment on the immune system. The study aimed to investigate and analyze the impact of the SARS-Cov-2 viral infection on mortality from oncohematological diseases.Methods: Data for the retrospective cohort study was obtained from patient electronic medical records. CVI was confirmed by a positive PCR test for SARS-Cov-2 RNA and chest computed tomography. All patients underwent a determination of the disease status at the time of admission to the department. Further, the therapy performed was estimated, and a descriptive analysis of the treatment results was carried out.Results: From July 2020 to July 2021, 56 patients with hemoblastosis and hematopoietic depression with concomitant CVI were treated in the CVI-1 department of the National Research Oncology Center (Astana, Kazakhstan). During this period, 2 patients died, and the mortality rate was 3.6%, while at the specialized hematology department, the mortality rate in 2020 amounted to 2.9% (26 deaths per 904 patients).Conclusion: Our department’s results conclude that without systemic antitumor therapy for hemoblastosis and achieving remission, the treatment of infectious complications will be ineffective. SARS-CoV-2 infection during or after systemic anticancer therapy does not dramatically affect mortality from COVID-19.
Identification of the Source of Energy Going to Radiation of Acoustic and Electromagnetic Waves by an Oscillating Charged Drop
Authors: Grigor’ev A. I. , Kolbneva N. Yu. , Shiryaeva S. O.
Published: December 2024

The source of energy for the generation of electromagnetic radiation by an oscillating charged drop of viscous liquid is discussed. It is shown that the source of electromagnetic radiation is the thermal energy released in the drop during
Purification of Alpha-Amylase Produced by Aspergillus niger CNMN FD 06 under Submerged Cultivation in the Presence of TIO2 Nanoparticles and the Coordination Compound of Sr(II) with Polydentat Ligand
Authors: Ciloci A. A. , Bulimaga V. P. , Clapco S. F. , Labliuc S. V. , Dvornina E. G.
Published: December 2024

The stimulatory effect of TiO2 nanoparticles and of the coordination compound of Sr(II) with a polydentate ligand on the amylase activity was established under submerged cultivation of the micromycete strain Aspergillus niger CNMN FD 06. After purification by gel-filtration on the column of PAD-10 and the ion exchange chromatography on the Hi-TrapTMQ column, an increase in the specific activity of α-amylase in the case of the variants with the addition of TiO2 nanoparticles and coordination compound of Sr(II) up to 15523 and 14656 U/mg, respectively, compared to the control version 12037 U/mg. The yield of α-amylases after purification was also higher, with an increase of 31 and 20%, respectively, compared to that of the control variant. The SDS-PAGE analysis of the isolated proteins revealed the presence of two bands in the active fractions with an apparent molecular mass equal to 65 and 40 kDa, with a more abundant band with a molecular mass of 65 kDa i
A Robust Initial Basic Subset Selection Method for Outlier Detection Algorithms in Linear Regression
Authors: Satman Mehmet Hakan
Published: December 2024

The main motivation of this study is to develop an efficient algorithm for diagnosing and detecting outliers in linear regression up to a reasonable level of contamination. The algorithm initially obtains a robust version of the hat matrix at the linear algebra level. The basic subset obtained in the first stage is improved through concentration steps as defined in the fast-LTS (Least Trimmed Squares) regression algorithm. The method can be plugged into another algorithm as a basic subset selection state. The algorithm is effective against outliers in both X and Y directions by a rate of 25%. The complexity of the algorithm increases linearly with the number of observations and parameters. The algorithm is quite fast as it does not require iterative calculations. The success of the algorithm against a specific contamination level is demonstrated through simulations.
From Patriot to Pauper: The Erratic Fortunes of David Poe Sr.
Authors: Sullivan Dwight H.
Published: December 2024

Despite the historical significance of Edgar Allan Poe’s paternal grandfather, no coherent biography of him exists. This article fills that historiographical gap. It presents David Poe Sr.’s rise from wheelwright to Revolutionary War quartermaster, postbellum merchant, and elected official followed by his financial collapse and imprisonments for debt. As a child, David Poe emigrated with his parents from Ulster Province, Ireland, to colonial America. By 1775, he was a Baltimore wheelwright and avid patriot. Extensive surviving documentation of Poe’s Revolutionary War service as a quartermaster remains largely untapped by his grandson Edgar’s biographers. Those documents reveal that Poe provided crucial logistical support to the American and French allies’ Yorktown campaign that ended the Revolutionary War. Similarly overlooked are archival primary sources concerning Poe’s time as a Baltimore City councilman and, later, his dismissal as the municipality’s inspector of fish. Indicia of his financial ruin have also remained unexplored. Relying extensively on primary source material, this article offers a narrative account of David Poe Sr.’s life. It focuses on his Revolutionary War activities, postbellum political offices, insolvency, and service as a septuagenarian soldier at the Battle of North Point during the War of 1812.
Digital Transformation of Public Authorities in Wartime: The Case of Ukraine
Authors: Oliychenko Igor , Ditkovska Maryna , Klochko Anatolii
Published: December 2024

Digital transformation has led to significant improvements in public administration systems. The results of recent research demonstrate undeniable achievements in this field. However, the challenges of rational exchange of information within state administration bodies and their interaction during wartime remain insufficiently considered. This study analyzes the current state of e-government in Ukraine, identifies existing problems, and proposes ways of improving the situation. The methodology is based on qualitative and quantitative analyses. The novelty of this research lies in its methods, which apply a matrix model of data flows. This article offers recommendations for improving e-governance in Ukraine.
Plato on the Goodness of Difference: The Convertibility of the Transcendentals in the Sophist
Authors: Brown Ryan Michael
Published: December 2024

This article argues that Plato’s Sophist can be understood as promoting a rudimentary version of the medieval notion of the “convertibility of the transcendentals,” that is, that there are certain properties of being, such as unity and truth, that have the same extension as being but add conceptual content to being. Histories of the doctrine of the transcendentals tend to trace transcendental thought back no earlier than Aristotle and thus ignore the relevance of Plato generally and the Sophist specifically. This article argues that the Eleatic Stranger’s discourse on the five “greatest kinds” (megista genē) indicates that Sameness and Otherness fulfill the criteria of transcendentality. The article uses this analysis to provide an avenue for further study of Platonic metaphysics in the hope that the notion of “convertibility of the transcendentals” will aid interpreters in understanding how to bring together Plato’s various accounts of what is metaphysically ultimate. This article suggests that, in addition to sameness and otherness, unity, goodness, truth, and beauty are also transcendentals within Platonic metaphysics. The article concludes by implying that difference (i.e., Otherness) must be ontologically good in Platonic thought, contrary to the common criticism that Platonism both denigrates difference and subordinates it to sameness.
Biogenic Synthesis, Characterization and Degradation of Methylene Blue Dye of Zinc Oxide Nanoparticles from Different Zinc Salts Using Cinnamomum verum Extract
Authors: Aydoğdu Burcu , Ünal İlkay
Published: December 2024

In this study, zinc oxide nanoparticles (ZnONPs) were synthesized using Cinnamomum verum extract from different zinc salts such as zinc acetate, zinc nitrate, zinc sulfate, and zinc chloride. The synthesized ZnONPs were characterized using X-ray diffraction (XRD), dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FT-IR), and transmission electron microscopy (TEM). Additionally, The photocatalytic activities of ZnO nanoparticles were tested in the presence and absence of sunlight. Cinnamomum verum extract was analyzed for DPPH radical scavenging activity and total phenolic content (TPC). The study results showed that the type of zinc salt used significantly affects the morphology, size, and crystal structure of the ZnO nanoparticles. ZnONPs synthesized from zinc acetate (ZnONPsA) showed superior photocatalytic activity in the presence and absence of sunlight.
THE IMPACT OF ADDITIONAL CUSTOMS DUTY DECISION OF THE USA ON STEEL EXPORT OF TÜRKİYE
Authors: Özaytürk İbrahim
Published: December 2024

Steel products have an important spot among the export commodities of Türkiye to the United States of America (USA). The export of steel goods to the USA has been steadily rising over the years, along with other export commodities to the USA. Nevertheless, the imposition of a 25% supplementary customs tariff in 2018, motivated by political considerations, posed significant challenges for enterprises operating in the steel export industry. This study investigates how the USA's higher customs charge continues to affect Turkish steel in the industry. It analyzes monthly data from 2018 to 2023. Enders and Lee (2012) developed the Fourier ADF (FADF) unit root test to analyze the stationarity qualities of the examined series. If the series exhibits stationarity, the supplementary customs duty decision will have a transitory impact. Nevertheless, if the series possesses a unit root, the impact of the supplementary customs duty determination will be enduring. Based on the observed data, it can be concluded that the series does not exhibit any unit roots. Simply put, the FADF test rejects its primary hypothesis, indicating the presence of stationarity.
Türkiye’deki Sürdürülebilir Mavi Ekonomi ve Deniz Yönetişimi İmkanlarının Değerlendirilmesi: Bakanlıklar Düzeyinde Bir İnceleme
Authors: Karlı Aygün
Published: December 2024

Kamu politikası yaklaşımı açısından değerlendirildiğinde denizel çevre politikaları, son on beş senedir önemini arttıran bir konu halini almıştır. Devletler, uluslararası örgütler, sivil toplum kuruluşları ve üniversitelerin ortak bir çözüm arayışı içerisinde oldukları temel konu ise okyanus ve denizlerdeki kirliliğin azaltılması ve okyanus ile denizlerden sürdürülebilir bir şekilde nasıl yararlanılacağıdır. Mavi büyüme ve mavi ekonomi kavramlarının 2000’lerin ortalarından itibaren öneminin artmasıyla birlikte okyanus ve denizlerden yararlanılma süreçlerine kamu politikaları açısından müdahale edilme gerekliliği de önemli bir süreç olarak ortaya çıkmıştır. Bu doğrultuda, kamu politikalarının yapıcısı ve uygulayıcısı olan kamu otoritelerinin balıkçılık, su ürünleri yetiştiriciliği, gemi yapımı/sökümü/geri dönüşümü, liman yönetimi, kıyı turizmi, denizel biyoçeşitliliğin korunması, iklim değişikliğinin etkileri, derin deniz maden araştırmaları ve denizel yenilenebilir enerji gibi pek çok konuyu içerisinde barındıran deniz politikalarını düzenleme, uygulama ve yönetme süreçleri de karmaşık bir yapıya neden olabilmektedir. Bu karmaşık yapının anlaşılabilmesi için, devletlerin ilgili yasal düzenlemeleri sonucunda ortaya çıkan sürdürülebilir mavi ekonomi ve deniz yönetişimi konularının araştırılması ve bu konu başlıkları çerçevesinde devletin ilgili birimlerinin yetki süreçlerinin incelenmesi gerekmektedir. Bu süreçlerin incelenmesi, bu çalışmada, çevre politikası entegrasyonu kavramı çerçevesinde değerlendirilmiş ve Türkiye özelinde, bakanlıkların sürdürülebilir mavi ekonomi ve deniz yönetişimi konularındaki entegrasyonu incelenmiştir. Bu entegrasyonun incelenmesinin ön koşulu ise Türkiye’deki bakanlıkların sürdürülebilir mavi ekonomi ve deniz yönetişimi konusundaki görev alanlarının belirlenmesi ve çevre politikası entegrasyonu konusundaki kapasitelerinin ölçülmesidir. Son olarak, çevre politikası entegrasyonu çerçevesinde değerlendirilmiş olan Türkiye’nin sürdürülebilir mavi ekonomi ve deniz yönetişimi imkanları, Türkiye’deki denizel çevre politikalarının görev ve yetki karmaşası yaratıp yaratmadığı açısından da tartışılmıştır. Değerlendirmenin temel ölçütü olarak 1 Numaralı Cumhurbaşkanlığı Teşkilatı Hakkında Cumhurbaşkanlığı Kararnamesi ele alınmış ve bakanlıkların denizel çevre politikalarıyla ilişkili olarak sürdürülebilir mavi ekonomi ve deniz yönetişimi konularındaki görev ve yetki hususları ilgili kategorilere ayrılarak incelenmiştir.
Türkiye’de Kadın Cinayetlerinin Medyada Temsili: “Farkındalık” mı, “Rol Modeli” Oluşturma Riski mi?
Authors: Oğuz Cihan
Published: December 2024

Kadın cinayetleri konusu Türkiye’de uzun yıllardır medyanın başlıca gündem maddelerinden birini oluşturmaktadır. Toplumda tepki yaratan bu tür olaylar doğal olarak medyanın da ilgisini çekmekte, gazetelerde ve TV haberlerinde ilk sıralarda yer almaktadır. Normalde kadına yönelik şiddet haberlerinin bir farkındalık yaratması ve bu tür şiddet olaylarının önlenebilmesi yolunda yasal/toplumsal adımlar atılmasına gerekçe olması beklenirken, dönem dönem tersi örneklerin görülmesi akıllarda değişik soru işaretleri bırakmaktadır. Bir tarafta, medyanın kadına yönelik şiddet konusunda duyarlı davranılması ve farkındalık oluşturulması için topluma mesaj verme beklentisi, ama diğer tarafta da bu konuda harekete geçme potansiyeli olan saldırganlara dolaylı yönden taktik ve cesaret verme riski bulunmaktadır. Bu çalışmada, kadın cinayetlerinin medyada nasıl temsil edildiği analiz edilerek, haberlerde psikolojik dengeyi sağlama konusunda öneriler geliştirilmiştir. Bu kapsamda, Türkiye’de yazılı basının en önemli gazetelerinden Hürriyet’te ve gazetenin web sitesinde 2024 yılı Mart ayında yayımlanan kadına şiddet konusundaki 8 haber eleştirel söylem analiziyle irdelenmiştir. Sonuçta, bu haberlerden sadece biri “farkındalık” yaratacak, diğer yedisi ise “yeni cinayetlere kapı aralayabilecek” türden haberler olarak değerlendirilmiştir.
Narrar espaços construídos por constelações de imagens
Authors: Ribeiro-da-Costa Ana Carolina , Simões Rozestraten Artur , Reis-Velloso Leandro Manuel
Published: December 2024

O presente trabalho apresenta requisitos para uma interface web experimental que estimula a compreensão do ambiente construído ao mobilizar narrativas visuais que construam uma forma sensível e relacional entre diversos objetos do imaginário arquitetônico e urbanístico. A partir de dois experimentos realizados como caminhadas fotográficas nas cidades de São Paulo e do Recife, foram produzidas alternativas de representação destas experiências que responderam à pergunta: "Que outras formas de representar a experiência de caminhar pela cidade seriam possíveis para além da imagem única e estática?". Os resultados obtidos serviram como guia para a elaboração de requisitos para uma interface digital para o acervo hospedado no ARQUIGRAFIA. Em grande medida, o projeto experimental de interface obtido também pode ser considerado como uma atualização tecnológica da metáfora das constelações de imagens de Aby Warburg.
Cell Secretome from Mesenchymal Stem Cells for Periodontal Regeneration
Authors: Yan Fuhua , Xiao Yin , Chen Bin , Li Lili , Zhang Xiaoxin , Liu Qing
Published: December 2024

Review
Cell Secretome from Mesenchymal Stem Cells for Periodontal Regeneration

Bin Chen 1,†, Lili Li 1,†, Xiaoxin Zhang 2, Qing Liu 1, Yin Xiao 3,* and Fuhua Yan 1,*
1 Department of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China
2 Central Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China
3 School of Medicine and Dentistry & Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4222, Australia
* Correspondence: yin.xiao@griffith.edu.au (Y.X.); yanfh@nju.edu.cn (F.Y.)
† These authors contributed equally to this work.

Received: 6 November 2024; Revised: 12 December 2024; Accepted: 16 December 2024; Published: 23 December 2024
 

Abstract: Periodontitis affects approximately 50% of the global adult population and results in varying degrees of periodontal destruction. The regeneration of periodontal tissue is in great demand but is currently difficult to achieve. The cell secretome from mesenchymal stem cells (CSmsc) has shown promise in promoting periodontal regeneration and is a translational alternative for mesenchymal stem cell (MSC)-based therapy. The practical components of CSmsc are soluble secretions and extracellular vesicles. The mechanisms of CSmsc-induced tissue regeneration may lie in its regulation of the local microenvironment, modulating immune cells such as macrophages and stimulating local host MSCs, a cell population with a direct effect on tissue regeneration. Therefore, CSmsc has been suggested as a promising cell-based product for future periodontal regenerative therapy. Hence, more studies should be conducted to analyse the effective components of the MSC secretome, explore the underlying mechanisms, and obtain functional CSmsc for clinical translation in periodontal regeneration.
Impaired Osteoclastogenesis in Medication-Related Osteonecrosis and Potential Clinical Management with BMP-2
Authors: Xu Chunfeng , Xiao Yin , Wu Yiqun , Bakker Astrid , Liu Yuelian
Published: December 2024

Review
Impaired Osteoclastogenesis in Medication-Related Osteonecrosis and Potential Clinical Management with BMP-2

Chunfeng Xu 1, Yin Xiao 2, Yiqun Wu 1, Astrid Bakker 3 and Yuelian Liu 3,*
1 Department of Second Dental Center, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Centre for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai 201900, China
2 School of Medicine and Dentistry & Institute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, QC 4222, Australia
3 Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands
* Correspondence: y.liu@acta.nl; Tel.: +31-205980626

Received: 5 November 2024; Revised: 18 December 2024; Accepted: 19 December 2024; Published: 23 December 2024
 

Abstract: Medication-related osteonecrosis of the jaw (MRONJ) is a rare, but severe, complication of applying inhibitors of osteoclasts, specifically bisphosphonates and the monoclonal antibody of receptor activator of nuclear factor kappa-Β ligand (RANKL), inhibitors of angiogenesis, and some chemotherapeutics. MRONJ is painful for the patients, while current treatments are unsatisfactory. Thus, it is imperative to understand the etiology and pathogenesis of MRONJ to improve treatment options and enable prevention. Various hypotheses have been proposed over the years to elucidate the pathogenesis of MRONJ. Noticeably, impaired osteoclastogenesis shines some light on novel preventive and treatment strategies. In this review, we summarized the current understanding of the role of osteoclastogenesis in the development of MRONJ and have put forward a hypothesis concerning the application of BMP2 in the clinical management strategy for MRONJ.
IMPLEMENTASI KURIKULUM 2013 PAUD DI RA NURUL ISLAM II MUARA BUNGO
Authors: Fatimah Eka Ristiani , Zulghafrin Zulghafrin
Published: December 2024

Tujuan dari penelitian ini adalah menjleaskan implementasi atau penarapan kurikulum pembelajaran Pendidikan Anak Usia dini tahun 2013 di RA Nurul Islam II Muara Bungo. Kurukulum dalam sebuah lembaga adalah suatu yang penting untuk di perhatikan dalam sebuah tujuan pendidikan. Pelaksanaan pembelajaran dalam kurikulum PAUD 2013 memakai metode pembelajaran tematik, dibingkai dengan pendekatan saintifik, untuk memantik pendidikan, dan untuk memantau perkembangannya menggunkan penilaian autentik. Metode dalam Penelitian ini menggunakan, skualitatif, untuk mencari dan mengumpulkan data didapatkan dengan observasi, melalui wawancara dan merekamnya atau dokumentasi. Adapun subjek penelitiannya yaitu kepala sekolah dan guru yang mengajar di RA Nurul Islam II, Kabupaten Bungo. Penelitian ini menghasilkan hal tentang implementasi atau penerapan pendidikan anak usia dini kurikulum 2013, yang diterapkan dilapangan, baik dari perencanaan pembelajaran, bahan pembelajaran, pelaksanaan pembelajaran dan teknik penilaian yang digunakan.
TRANSFORMASI PENERAPAN MODEL PEMBELAJARAN SENTRA (BCCT) MENJADI MODEL PEMBELAJARAN PANGGUNG DI PAUD SEKOLAH ALAM PELOPOR BANDUNG
Authors: Mardiani Desika Putri , Widyaswari Monica , Susanto Shobri Firman , Yusuf Ali
Published: December 2024

It is necessary to apply a suitable learning model for early childhood to explore every potential of students. Of course, learning media that are easy to find and local elements must be included so children can recognize themselves and know where they come from. The purpose of this study is to examine the transformation of the learning model into a stage learning model organized by PAUD Sekolah Pelopor Alam, Bandung. The research method uses a qualitative approach with data collection techniques in the form of interviews, indirect observation, and documentation. The data analysis used is Miles and Huberman analysis, while the validity test uses extension of observation, persistence of observation, and triangulation of sources. Research results showed that the implementation of early childhood education by applying the learning center model is less able to bring out the elements of localization in the Rancaekek, Bandung, so the founder switched to using the stage model, which is closer to the daily life of children. The stage model is inspired by the center model, which consists of several sub-sections. If the center model consists of a preparation center, an art center, a natural materials center, a beam center, and a role-play center. Whereas in the application of the stage model, There are eleven sub-sections developed, namely the stage of play, cooking stage, development stage, exploration stage, science stage, cooking stage, kasundaan stage, development stage, imtak stage, gardening stage, and livestock stage.
Kadınların Ekolojik Kaygıları ve Çocukları Hakkındaki Gelecek Endişeleri: Küresel Problemlerin Sonuçları mı?
Authors: Kılıç Leyla Sümeyye , Kocoglu Tanyer Deniz
Published: December 2024

Amaç: Çalışma başta iklim değişikliği olmak üzere 21.yy krizlerinden olan pandemi, yoksulluk, göç, savaş vb. sosyal problemlerin kadınların ekolojik kaygıları ve çocukları hakkında gelecek endişelerine etkisinin incelenmesi amacıyla yapılmıştır.
Yöntem: Bu çalışmada tanımlayıcı ilişkisel tasarım kullanılmıştır. Çalışma verileri Nisan-Haziran 2023 tarihleri arasında anaokullarında eğitim gören 4-6 yaş arası çocuğu olan 148 kadın ile yürütülmüştür. Veri toplama aracı olarak araştırmacılar tarafından hazırlanan anket formu ile Eko-Anksiyete Ölçeği kullanılmıştır. Veriler SPSS 27.0 programında parametrik analizler kullanılarak incelenmiştir.
Bulgular: Çalışmaya katılan kadınların yaş ortalaması 35.33±5.92 yıl ve sahip olduğu çocuk sayısı ortalaması 2.26±1.04’dür. Kadınların %70.1’i geleceğe olumsuz bakmaktadır. Kadınlar en fazla gelecekte su sıkıntısı (%81.8), gıda kıtlığı (%72.3) ve göç nedeniyle toplumsal yaşantının bozulacağı korkusu (%66.2) yaşamaktadır. Ekonomik düzeyi düşük olanların çevre sorunlarını daha çok düşündükleri, kırsalda yaşayanların daha çok kaygı duydukları; savaş, yoksulluk, göç nedeniyle ekonomik korku ve işsiz kalma korkusu yaşayanların yaşamayanlara göre çevre sorunlarını daha çok düşündükleri ve daha fazla kaygı yaşadıkları saptanmıştır.
Sonuç: Kadınların ekolojik farkındalıklarının arttırılması için çalışmaların yapılması ve gelecek kaygılarını ele almada desteklenmeleri gerekmektedir.
Yetişkin Bireylerde Sağlık Arama Davranışı, Sağlık Sorumluluğu ve Etkileyen Faktörler
Authors: Çın Dilara , Demir Esma , Şen Mehmet , Kılıç Özge , Erol Saime
Published: December 2024

Amaç: Bu çalışma, yetişkin bireylerin sağlık arama davranışlarını, sağlık sorumluluklarını ve etkileyen faktörleri belirlemek amacıyla yapıldı.
Yöntem: Araştırma, tanımlayıcı ilişki arayıcı tasarım ile İstanbul ilinin Anadolu Yakası’nda bulunan bir Aile Sağlığı Merkezinde (ASM) gerçekleştirildi. Araştırmanın örneklemini ASM’ye kayıtlı 605 yetişkin birey oluşturdu. Veriler, Sosyo-Demografik Özellikleri Tanılama Formu, Sağlık Arama Davranışı Ölçeği (SADÖ) ve Sağlıklı Yaşam Biçimi Davranışları Ölçeği’nin Sağlık Sorumluluğu Alt Boyutu kullanılarak toplandı. Verilerin değerlendirilmesinde, tanımlayıcı istatistiklerin yanı sıra Independent Samples T-Test, One-Way ANOVA testi ve Pearson korelasyon analizi kullanıldı.
Bulgular: Yetişkinler, online sağlık arama davranışı alt boyutundan 16.09±4.41, profesyonel sağlık arama davranışı alt boyutundan 12.50±2.10, geleneksel sağlık arama davranışı alt boyutundan 12.90±1.62 puan aldı. Sağlık sorumluluğu alt boyut puan ortalamasının 20.47±4.13 olduğu saptandı. Sağlık sorumluluğu alt boyutu ile online sağlık arama davranışı alt boyutu arasında pozitif yönde, yüksek düzeyde; sağlık sorumluluğu alt boyutu ile profesyonel, geleneksel sağlık arama davranışı alt boyutları arasında ise pozitif yönde, orta düzeyde anlamlı korelasyon bulundu (p