bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Study on the Prevalence of Escherichia coli and it’s Antibiogram in Saum from Three Different Storage Places in Household at Mizoram
Authors: Debbarma Binipi , Ralte Lallawmzuali , Motina E. , Lalmuanpuia Joy , Tolernkhomba T.C. , Roychoudhury Parimal
Published: October 2023

Background: Saum is a very important traditional food item of the Mizo society in Mizoram, North East India; but there is scanty scientific study and reports on Saum. The present study has been conducted to study and compare the prevalence of E. coli in Saum from three different storage places such as storage/keeping Saum under the sun (24-38°C) during hot part of the day, inside the refrigerator (3-4°C) and near the cooking fire (30-50°C) at home. Methods: The study was conducted from May, 2022 to November, 2022. A total of 105 Saum samples were collected from three different storage places comprising of 35 samples from each storage places and then analysed for the presence of foodborne pathogen E. coli and it’s virulence genes (stx1, stx2, elt, est genes) by conventional method and PCR. All the E. coli isolates were subjected to 12 different antibiotics for antimicrobial resistance pattern by disc diffusion method. Result: The overall prevalence of E. coli from 105 samples was 7.62% (8/105) comprising of 5.71% (2/35) from the storage place under the sun, 2.86% (1/35) from the refrigerator and 14.29% (5/35) near the cooking fire and no presence of virulence genes of E. coli was detected in the present study. The antimicrobial resistance pattern of all the 8 E. coli isolates showed the highest resistance to Cefazolin (100%) followed by Imipenem (37.5%). The present work will be a complementary contribution among Mizo society to know the best and safest storage places of Saum in regards to public health point of view.
Effectiveness of Fungicides against Colletotrichum lindemuthianum Causing Anthracnose of Green Gram [Vigna radiata (L.) Wilczek]
Authors: Purushotham Pooja , Rakholiya K.B. , Vanani K.D.
Published: October 2023

Background: Anthracnose is currently a severe threat to green gram cultivation in India. In vitro bioassay and glasshouse studies were performed to evaluate the effectiveness of different fungicides against Collectotrichum lindemuthianum. Methods: The current investigation was conducted at the Department of Plant Pathology, N.M. College of Agriculture, Navsari Agricultural University, Navsari, Gujarat in 2020-21. The poison food technique assessed the efficacy of systemic, non-systemic and combination fungicides against C. lindemuthianum. The management study was also carried out from the best-performing bioassay treatments and evaluated in the glasshouse. Result: At 500 ppm, carbendazim 50 WP and propiconazole 25 EC inhibited 100% of mycelial growth out of six systemic fungicides tested while in non-systemic fungicides, mancozeb 75 WP and chlorothalonil 75 WP inhibited the test pathogen the most at 2500 ppm. Among the combi-fungicides tested at 500 ppm, carbendazim (12%) + mancozeb (63%) 75 WP and captan 70% + hexaconazole 5% 75 WP inhibited pathogen mycelial growth the most significantly more than the untreated control. In glasshouse studies, the lowest disease index was found in two foliar sprays of carbendazim 50 WP @ 1.0 g/l, propiconazole 25 EC @ 2.0 ml/l and captan 70% + hexaconazole 5% @ 0.6 g/l spaced 15 days apart. On the other hand, seed treatment of carbendazim 12% + mancozeb 63% @ 3.0 g/kg seed and mancozeb 75 WP @ 3.0 g/kg seed had the lowest disease index compared to control.
How Expert Are the Experts? Child Custody Evaluations in Situations of Domestic Violence in Italy
Authors: Feresin Mariachiara , Santonocito Marianna
Published: October 2023

In recent decades, scholars and professionals have investigated the courts’ treatment of mothers and children who claim that an ex-partner/father is abusive, especially in child custody proceedings. In Italy, Laws 54/2006 and 154/2013 established that joint-custody and coparenting are critical to ensure the best interest of the child. In the process of custody determination, judges can appoint an expert to assess parenting skills. The aim of this qualitative study was to investigate the knowledge, opinions, and practices of the Court-Appointed Experts (CAEs) in child custody disputes in cases involving allegations of domestic violence (DV). Semistructured face-to-face interviews were conducted with 15 CAEs; the interviews’ transcripts were analyzed with qualitative content analysis. Results suggested that in the management of child custody cases, most CAEs showed: strong prejudices against women victims of DV, who were often blamed and/or secondarily victimized; adherence to controversial models (e.g., parental alienation syndrome) and characterization of mothers as “alienators”; poor knowledge of DV and relevant laws. CAEs’ overlooking DV underlines the urgent need to develop and implement guidelines on child custody decision-making in the context of DV.
Defiance and Strength: A Qualitative Study of Sex Trafficking Survivor–Advocate Coping Strategies
Authors: Preble Kathleen M. , Twis Mary , Kollmeyer Samantha , Greenwood Don
Published: October 2023

In the two decades since federal law prohibited the trafficking of humans for sexual or nonsexual services, researchers have generated knowledge related to the mental and physical health consequences of the experience, the individual and environmental factors that facilitate exploitation, and the best practices for prevention and intervention. Despite these advances in knowledge about human trafficking, relatively scant research has explored the resiliencies of survivors, as a deficit-based narrative persists when exploring and contemplating survivor experiences. While the movement increasingly recognizes the need to situate the survivor voice in service delivery, advocacy, and research, an inquiry that values survivor strengths remains nascent. Using the Intersectional-Standpoint Methodology (ISM) and phenomenology, this qualitative study explores the nuances of resiliency during exploitation and exit among seven sex trafficking survivor–advocates in a small midwestern state. Themes related to coping strategies, intrapersonal coping skills, and interpersonal coping skills were revealed and contextualized through the four variables proposed in ISM. Implications for service provision and policy are provided.
Performatividad de la formación de maestros e identidades docentes: antecedentes investigativos
Authors: Orozco William
Published: October 2023

Este artículo de revisión busca realizar una radiografía del estudio de las “identidades docentes” desde enfoques no afirmativos, acercándose a perspectivas deconstructivas y críticas. Esto, de modo que se adviertan dinámicas performativas y relaciones de poder que median la formación docente. Para ello, se utiliza el método de revisión sistemática que procura orientar y delimitar la exploración de estudios y su selección según un foco de búsqueda. Los resultados advierten cuatro líneas temáticas que permiten acrisolar los modos performativos en que operan las “identidades docentes”. Estas líneas son la relación entre identidades, creencias y mitos, el rol de las identidades idealizadas en cuanto reguladoras de la profesión docente, la preponderancia del cuerpo como escenario simbólico donde se cifran estas normas y el carácter prescriptivo de ciertas identidades socialmente construidas y designadas. Se pone de manifiesto la necesidad de revisar en el país asuntos como las teorías subjetivas (Lay Theories), procesos de exclusión generados por identidades, efectos que tienen estos designios del poder sobre los cuerpos de los maestros y el rol que tienen ciertas identidades dadas por sentado.
Principio de progresividad y no reversibilidad en educación inclusiva para población con discapacidad en Colombia
Authors: Correa Jorge
Published: October 2023

Este artículo presenta la construcción reflexiva, producto de un proyecto de investigación centrado en analizar el principio de progresividad y no reversibilidad en la educación inclusiva para personas con discapacidad en Colombia, el cual retoma los Decretos que le han dado soporte para su implementación, así como la experiencia de 33 personas con discapacidad que han transitado por el sistema de educación, aun activas en la educación superior en la ciudad de Medellín. Su estudio se orientó desde la perspectiva crítica y analítica utilizando las técnicas de análisis documental y grupo focal, concluyendo que en el principio de progresividad y no reversibilidad se reconocen progresos políticos, conceptuales y procedimentales que han transversalizado el sistema educativo, desde la educación infantil a la superior; su mayor obstáculo radica en la disponibilidad de recursos para la continuidad y sostenibilidad de estrategias requeridas en la educación inclusiva.
The Drivers and the Changes of the Digital Economy and the Skills Gap in the Formal Education
Authors: Reyes Jose
Published: October 2023

The digital economy is changing the way people work and creating new skills and competencies. But the formal education system is often behind in giving learners the skills they need to succeed in the digital economy. This paper looks at how the digital economy is changing and how the skills gap in formal education is getting bigger. It looks at different research works that show how to bridge the skills gap and teach learners relevant skills for the digital economy. It also discusses some of the best practices and recommendations for improving the quality and relevance of formal education in the digital era.
A judicialização das questões de saúde no estado de Roraima
Authors: Liandro Praia Martins Bruno , Lucas de Moura Palotti Pedro , Mendonça Milton , Augusto Magalhães Luiz
Published: October 2023

A Constituição Federal de 1988 prevê o fornecimento de saúde universal ao cidadão como obrigação primária do Estado e na prática concede permissão para que o cidadão ao se verificar impedido de obter o tratamento ou medicamento que necessita busque o Poder Judiciário como a forma de obtê-lo. Nesse sentido, através de ampla pesquisa e coleta de dados oriundos do Governo do Estado de Roraima e do próprio Poder Judiciário estadual, Sistema Processual Digital de Processos (PROJUDI), iniciados entre 2015 e 2018, e nas prestações de contas e relatórios emitidos pelo governo do estado de Roraima no mesmo período, procedeu a verificação da judicialização das questões de saúde no estado e os impactos das sentenças exaradas localmente sobre o financiamento do sistema de saúde estadual e sobre o próprio fornecimento dos serviços de saúde. Entre outros resultados alcançados por esta pesquisa, destaca-se que especialmente em relação a 2017 e a 2018, o estado de Roraima adotou uma postura de permissão e passividade em relação aos bloqueios judiciais em suas contas como forma de prover ao cidadão o medicamento e tratamento buscado, simplesmente por ser a forma mais rápida de garantir os direitos a saúde desses.
Religious Values in The Funeral Procession on The Datuk Wisdom
Authors: Samiran Fahmil , Helfi Helfi , Hendri Hendri , Noor Ahmad Yunus Mohd
Published: October 2023

In Minangkabau may not be the only custom that occurs Salingka Nagari, but each country has its unique features. This article describes the religious value of the Datuk burial process in Minangkabau. This study investigates the religious values in the traditional ceremony of the death of a Datuk called Osong Kapali. This study uses qualitative research with data collection using interviews and documentation methods. The first ceremony of Osong Kapali begins with baretong, mangkaji adaik, mancabiakan shroud, Osong Kapali, installation of adaik cloth, maroncak, natural speech, Manigo Ari. In the procession of Adat Osong Kapali there are religious values such as the value of worship, generosity, the value of trust and the value of gratitude for abun and sustenance.
60 poemas griegos
Authors:   Universidad Nacional Autónoma de México, Morábito Fabio ,   Instituto de Investigaciones Filológicas,   Centro de Poética, Berruecos Frank Bernardo ,   Universidad Nacional Autónoma de México,   Instituto de Investigaciones Filológicas,   Centro de Estudios Clásicos
Published: October 2023

El lector tiene a la vista una selección de sesenta poemas pertenecientes a trece poetas griegos de los siglos VII al V a. C., representantes de lo que se conoce como la poesía griega arcaica y, más específicamente, la poesía lírica, para distinguirla de la poesía épica. La lírica es la que está más próxima a nuestra concepción de la poesía, pues sus temas se centran en la vida de todos los días, con las ilusiones y los sueños, las pasiones y los placeres, los dilemas morales y los temores del individuo común y corriente. La poesía épica, en cambio, se centra en los héroes y las grandes hazañas, así como en las leyendas tradicionales transmitidas a través de la memoria de generación en generación. ¿Qué se entiende por "lírica" cuando hablamos de poesía lírica griega? ¿Cómo fueron las formas de canonización de los poetas llamados líricos y a través de qué procesos se fueron transmitiendo sus textos? Éstas, y muchas otras, son preguntas que a la luz de estos "poetas arcaicos", intentamos responder aquí.
El fructífero camino de Aurora M. Ocampo Remembranzas en el quinto aniversario de su deceso (1930-2018)
Authors:   Universidad Nacional Autónoma de México, Mandujano Jacobo Pilar ,   Instituto de Investigaciones Filológicas,   Centro de Estudios Literarios
Published: October 2023

A cinco años de la desaparición física de la maestra Aurora M. Ocampo el presente texo intenta recuperar su presencia a través de las distintas facetas de su convergencia: como académica, colega y otros lazos afectivos. El recuerdo es constante entre quienes tuvimos la ocasión de integrar el equipo del Diccionario de Escritores Mexicanos, convencidos de su legado y el compromiso adquierido con la Universidad y las letras mexicanas del siglo XX. Cada nueva etapa en este proyecto supone interrogar: ¿Cómo lo haría Aurora Ocampo? ¿Qué recomendaría? En estos tiempos que el tiempo apremia y debemos adaptarnos a los cambios tecnológicos, conceptuales y a las distintas modalidades de exposición de los escritores mexicanos, las enseñanzas de Aurora M. Ocampo son más que vigentes, y pertinentes desde el punto de vista simbólico y discipular: en el quinto aniversario de su deceso; los cincuenta y seis de su proyecto de Diccionario, y por extensión, los cincuenta del Instituto de Investigaciones Filológicas, institución a la que la Maestra dedicó más de la mitad de su vida.
En torno a un aniversario
Authors:   Universidad Nacional Autónoma de México, Franco Bagnouls Lourdes ,   Instituto de Investigaciones Filológicas,   Seminario de Edición Crítica de Textos
Published: October 2023

Todo camino andado es un triunfo, es una forma de saberse parte de un todo, nos dice en este artículo Lourdes Franco Bagnouls en el que reflexiona, teniendo como marco el 50 aniversario de la creación del Instituto de Investigaciones Filológicas (IIFL), sobre la memoria, el tiempo, las raíces, la formación misma del Instituto y, en un trazo conmovedor, evoca la memoria de personas con las que compartió vivencias entrañables que la formaron como humanista, en especial, a la Maestra Ana Elena Díaz Alejo. Todo aniversario es un buen motivo para recordar los orígenes o las raíces de lo que nos hace propietarios de una identidad. En el presente artículo, Lourdes Franco verbaliza su propia experiencia de vida para contarnos, de manera panorámica, la vida que ha pasado a través del cristal de su ventana.
Interpretación de las lenguas: filología, poética y traducción. Entrevista con Tatiana Bubnova - Seminario de Hermenéutica
Authors:   Universidad Nacional Autónoma de México, Bubnova Tatiana ,   Instituto de Investigaciones Filológicas,   Seminario de Hermenéutica
Published: October 2023

Siendo una adolescente, Tatiana Bubnova disfrutaba leyendo libros raros y difíciles que tenían comentarios que le parecían, a veces, más interesantes que la obra, ya que explicaban y aclaraban temas que no eran del todo conocidos para ella. Le sobrevino, entonces, una pregunta: ¿quién aporta ese conocimiento? Fue su curiosidad por saber más sobre lo que está detrás de ese proceso que Bubnova entró en el campo de la filología, cuya base, comenta, se encuentra en tres grandes aspectos: a) los textos en sí, su lectura y análisis; b) los comentarios que se hacen sobre ellos y, por supuesto, c) su traducción. En la presente entrevista habla sobre sus inicios como académica en el entonces recién creado Instituto de Investigaciones Filológicas de la Universidad Nacional Autónoma de México, y reflexiona sobre la importancia que en la actualidad tiene la labor de traducción, los estudios que se llevan a cabo en el Instituto y lo que puede aportar una rama de estudios como la hermenéutica para la mejor comprensión de todo lo que acontece en el dominio de las lenguas y las letras.
“Entre periodistas y literatos…”. Historia y líneas de trabajo del Seminario de Edición Crítica de Textos. Entrevista con Belem Clark y Pamela Vicenteño
Authors:   Universidad Nacional Autónoma de México, Clark de Lara Belem ,   Instituto de Investigaciones Filológicas,   Seminario de Edición Crítica de Textos, Vicenteño Bravo Pamela ,   Universidad Nacional Autónoma de México,   Instituto de Investigaciones Filológicas,   Seminario de Edición Crítica de Textos
Published: October 2023

n la presente entrevista escuchamos la voz de dos generaciones con intereses comunes pero con líneas de trabajo particulares. Por un lado, Belem Clark nos cuenta platica cómo fue que lo que inició como un taller, poco a poco y con base en resultados y la formación de una metodología clara de trabajo, fue ganando espacios hasta afianzarse como el actual Seminario de Edición crítica de Textos, dedicado a la literatura mexicana del siglo XIX y XX fundamentalmente. Comenta sobre proyectos de investigación que tienen como fin el rescate, la edición crítica y la interpretación de obras de autores como José Tomás de Cuellar o José María Roa Bárcena, entre otros. Por su parte, Pamela Vicenteño resalta la importancia de la primera etapa de la edición crítica, la recensio o búsqueda exhaustiva del material existente de un texto, en este caso, de periódicos y libros de la época. Al ser proyectos de largo aliento, comenta, es necesario conformar equipos de trabajo que conjunten bien la teoría y la práctica y es lo que destaca del Seminario. Además, platica sobre Roa Bárcena, autor que es motivo de sus actuales investigaciones y reflexiona sobre cómo el rescate de autores y textos decimonónicos es fascinante porque con base en los descubrimientos que se realizan, los argumentos se deben ajustar y la historia se debe ir reescribiendo.
Aurelia Vargas Valencia y su huella indeleble en la dirección del Instituto de Investigaciones Filológicas
Authors:   Universidad Nacional Autónoma de México, Méndez Aguirre Víctor Hugo ,   Instituto de Investigaciones Filológicas,   Centro de Estudios Clásicos
Published: October 2023

En la presente semblanza, Víctor Hugo Méndez Aguirre nos brinda un panorama de la gestión que de 2009 a 2013 ejerció al frente del Instituto de Investigaciones Filológicas (IIFL) como directora Aurelia Vargas Valencia. Poniendo hincapié en la mejora de la infraestructura del Instituto, se atendieron las necesidades tecnológicas, lo cual, por citar solo un ejemplo, puso a disposición de quien así lo desee la consulta abierta y gratuita en formato electrónico de las revistas que generan los Centros y Seminarios del Instituto. Además, propuso y estuvo al frente de proyectos académicos que enriquecieron el acervo cultural y bibliográfico, no solo de la institución, sino del país; destaca también su participación en la creación de una nueva licenciatura en Humanidades. Reconocida por su trato amable, respetuoso y equitativo, Aurelia Vargas Valencia dejó una huella indeleble e imprescindible al frente del IIFL.
(Con)figuraciones institucionales: la visión universitaria de Alberto Vital
Authors:   Universidad Nacional Autónoma de México, Shuttera Alejandro Sacbé ,   Instituto de Investigaciones Filológicas
Published: October 2023

Alberto Vital es, ante todo, una ejemplar figura institucional en el seno de la Universidad Nacional Autónoma de México. En este texto se resalta su dedicación, elocuencia, rigor académico, institucionalidad --en particular sus logros al frente del Instituto de Investigaciones Filológicas--, su congruencia personal y compromiso con la Universidad Nacional, de la que Vital forma parte como comunidad desde hace exactamente cincuenta años.
Morir para convertirse en libro: 400 años del Primer Folio de William Shakespeare
Authors:   Universidad Nacional Autónoma de México, Castro Santana Anaclara ,   Instituto de Investigaciones Filológicas,   Centro de Poética, Villanueva Noriega Gabriela ,   Universidad Nacional Autónoma de México,   Facultad de Filosofía y Letras, Canales Violante Zeidy Zady ,   Universidad Nacional Autónoma de México,   Facultad de Filosofía y Letras
Published: October 2023

En 1623, el cuerpo de William Shakespeare tenía ya siete años descansando en la tumba dentro de una iglesia en su pueblo natal de Stratford-upon-Avon. Su obra, sin embargo, estaba a punto de iniciar una nueva vida. Dos actores de su compañía teatral, John Heminge y Henry Condell, decidieron reunir, por primera vez en un solo libro, treinta y seis de las aproximadamente treinta y nueve piezas teatrales que Shakespeare escribió, en un afán por preservar la memoria y producción dramática de su antiguo maestro y colega, amén de también aprovechar las potenciales utilidades. El presente artículo, además de sumarse a tan significativas efemérides, intenta mostrar desde el ámbito de lo filológico cómo el teatro, en este caso, del medio anglosajón, emanado de la mayor de las glorias de ese mundo literario, pudo trascender su estatus de entretenimiento popular fugaz y llegó a ser considerado digno de ocupar --en dimensiones hiperbólicas-- un lugar perdurable y de prestigio en los estantes de la biblioteca.
A Privacy-preserving Approach to Effectively Utilize Distributed Data for Malaria Image Detection
Authors: Kareem Amer , Liu Haiming , Velisavljevic Vladan
Published: October 2023

Malaria is one of the life-threatening disease caused by the Anopheles mosquitoes affecting the human red blood cells. It is the global health concern which is quite common in tropical as well as sub-tropical parts of the World. Therefore, it is an important to have an effective computer aided system in place for early detection and treatment. State of the art machine learning techniques are used to detect the infected malaria cells from the pool of images. As the visual heterogeneity of the malaria dataset is highly complex and dynamic, therefore higher number of images are needed to train the machine learning models effectively. However, hospitals as well as medical institutions do not share the medical image data for collaboration due to general data protection regulation (GDPR) and data protection act (DPA). To overcome this collaborative challenge, our research is inspired to use the real-time medical image data while using the framework of federated learning (FL) framework that will ensure the data privacy while mutual collaboration of hospitals and medical institutes. We have used the state of the art machine learning models that include the Resnet50 and densenet in a federated learning framework. We have experimented both models in different settings and our preliminary results showed that the densenet model performed better in accuracy (75%) in contrast to resnet50 (72%) while considering 8 clients, while the trend is observed common in 4 clients with the similar accuracy of 94% and 6 client showed that the densenet model performed quite well with the accuracy of 92% while resnet50 achieving only 72%.
The Process to Plaque Rupture: The Role of Vasa Vasorum and Medial Smooth Muscle Contraction Monitored by Cardio-Ankle Vascular Index
Authors: Shirai Kohji , Hitsumoto Takashi , Sato Shuji , Takahashi Mao , Saiki Atsuhito , Nagayama Daiji , Ohira Masahiro , Takahara Akira , Shimizu Kazuhiro
Published: October 2023

A warning sign for impending cardio-vascular events is not fully established. In the process to plaque rupture, formation of vulnerable plaque is important, and oxidized cholesterols play important role in its progression. Furthermore, the significance of vasa vasorum penetrating medial smooth muscle layer and rich in atheromatous lesion should be paid attention. Cardio-ankle vascular index (CAVI) is new arterial stiffness index of the arterial tree from the origin of the aorta to the ankle. CAVI reflects functional stiffness in addition to structural stiffness. Rapid rise of CAVI means medial smooth muscle cell contraction, and strangling vasa vasorum. We reported rapid rise of CAVI in peoples after big earthquake, following high frequency of cardiovascular events. And we met several cases who showed rapid rise of CAVI a few weeks or months before suffering cardiovascular events. To explain these sequences of events, we proposed a hypothesis; A rapid rise of CAVI means medial smooth muscle contraction, strangling vasa vasorum, leading ischemia, necrosis of vulnerable plaque, then, the plaque ruptures. In individuals having high CAVI, further rapid rise of CAVI might be a warning sign for impending cardiovascular events. In such case, treatments to decrease CAVI had better to be taken soon.
The Prevalence of Hernias in a Tertiary Care Center: A Cross-Sectional Study
Authors: M.Abokhsab Mahmoud , Matalqah Husam , Matalkeh Lina , Yaseen Razan , Al-Hajjaj Maher , Matalkeh Mohammad , Alswalha Husni , Al Taani Basil , Alshloul Mohammad
Published: October 2023

Background: Abdominal wall hernias are a common condition that is seen in daily general surgery patients. However, still more researches are needed to be conducted regarding hernias. The aim of this study is to see the prevalence of hernias among patients admitted to the Department of Surgery of a tertiary care center.
Methods: A descriptive cross-sectional study was performed among patients who admitted to the department of surgery in a tertiary care center between 1 August 2023 and 20 September 2023. All patients data were extracted to an excel sheet.
Results: We had 760 patients who visited in this period. Only 272 patients (27.9 %) were diagnosed with hernias. We found 52.6 % of patients were male and 47.4 % of patients were female. The age between 46- 60 years old was the most to have hernias (97 patients). Inguinal hernias were the common among other types. Diabetes mellitus, hypertension, COPD, and hydrocele were found in 10.7 % of all patients.
Conclusion: The prevalence of hernias in this study was nearly to other studies that conducted in the same conditions. Early diagnosis and patient’s education are the corner stone to prevent morbidities and mortalities.
The Effect of Edge Activator Combinations using a Langmuir Technique in Transethosomal Formulations for Skin Delivery of Thymoquinone
Authors: Mohd Hana , Dopierała Katarzyna , Zidar Anže , Virani Amitkumar , Michniak-Kohn Bożena
Published: October 2023

The bioactive compound, thymoquinone (TQ), found in Nigella sativa seeds is known for its various therapeutic properties. Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, is known for its various therapeutic properties. However, TQ as a compound is challenging for a pharmaceutical formulator due to its hydrophobic nature and chemical instability, limiting its skin penetration. Transethosomes, as a formulation, provide an environment that enhances the solubility of TQ, stability, as well as skin permeation. To optimize TQ transethosomal formulations, we introduced a combination of surfactants namely nonionic Tween 20 and ionic sodium lauryl sulfate (SLS) or sodium lauroyl glutamate (SLG). These surfactants stabilize the formulation, reduce aggregation, and improve biocompatibility, as well as minimizing potential toxicity. Using the Langmuir monolayer technique, we fine-tuned the formulation composition and gained insights into its interfacial behavior. We conducted skin penetration studies using Rhodamine B as a model lipophilic compound to understand the skin penetration mechanisms. Our findings revealed that the transethosomes formulation, a combination of ionic and nonionic surfactants in the F2 formulation, resulted in the smallest particle sizes (115.4 nm) and demonstrated the highest skin permeation after 24 hours (267.13 μg/cm²), surpassing the control and ethosomal formulations. Additionally, this transethosomal formulation exhibited antimicrobial activity against S. aureus, with a zone of inhibition of 26.4 ± 0.3 mm. Importantly, we assessed the cytotoxicity of both ethosomes and transethosomes at concentrations ranging from 3.5 μM to 50 μM on HaCaT cell lines and found no cytotoxic effects in comparison to TQ solution controls. These results suggest the potential safety and efficacy of these TQ formulations and their further development in skin delivery.
Morlet Wavelet Neural Network Investigations to Present the Numerical Investigations of the Prediction Differential Model
Authors: Sabir Zulqurnain , ARBI Adnène , Hashem Atef F. , Abdelkawy M A
Published: October 2023

In this study, a design of Morlet wavelet neural networks (MWNNs) is presented to solve the prediction differential model (PDM) using the global approximation capability of genetic algorithm (GA) and local quick interior-point algorithm scheme (IPAS), i.e., MWNN-GAIPAS. The famous PDM is known as a variant of functional differential system that works as an opposite of the historical delay differential models. A fitness function is optimized using the mean square error by applying the GA-IPAS for solving the PDM. Three PDM examples have been presented numerically to check the authenticity of the MWNN-GAIPAS. For the perfection of the designed MWNN-GAIPAS, the comparability of the obtained results and exact results is performed. Moreover, the neuron analysis is performed by taking the 3, 10 and 20 number of neurons. The statistical observations have been performed to authenticate the reliability of the MWNN-GAIPAS for solving the PDM.
Mapping of Stripe Rust Resistance Gene Yr72 in Two Common Wheat Landraces
Authors: Chhetri Mumta , Miah Hanif , Wong Debbie , Hayden Matthew , Bansal Urmil , Bariana Harbans
Published: October 2023

Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a significant challenge to global wheat production. Common wheat landraces AUS27507 and AUS27894 displayed stripe rust resistance against several commercially prevailing Pst pathotypes. These genotypes were crossed with a stripe rust susceptible landrace AUS27229 to understand inheritance of resistance and to determine genomic location(s) of underlying gene(s). F3 generations of crosses AUS27507/AUS27229 and AUS27894/AUS27229 showed monogenic segregation for stripe rust resistance under greenhouse conditions. The absence of segregation for stripe rust response among the AUS27507/AUS27894-derived F3 population suggested that both genotypes carry the same gene. The stripe rust resistance gene carried by AUS27507 and AUS27894 was tentatively named YrAW4. Bulked segregant analysis placed YrAW4 in the long arm of chromosome 2B. The AUS27507/AUS27229 F3 population was enhanced to develop an F6 recombinant inbred line (RIL) population for detailed mapping of chromosome 2BL. DArT-based SSR, STS and KASP markers were employed to enrich the 2BL map. DArT-based STS markers sun481 and SNP marker IWB12294 flanked YrAW4 proximally (1.8 cM) and distally (1.2 cM), respectively. Deletion mapping placed sun481 in the deletion bin 2BL-5. All stripe rust resistance genes, previously located on chromosome 2BL, neither express infection type like YrAW4, nor are mapped in the deletion bin 2BL-5. Hence YrAW4 represented a new locus and was formally named Yr72. The robustness of IWB12294 marker in marker-assisted selection was demonstrated by amplification of and alternative allele to that linked Yr72 in 21 common wheat background.
Krallık Macaristanı’nda Bir Ceza Davasının İncelemesi: Eğri’den Gelen Türk’ün Cinayeti [1687]
Authors: AKIN Burak , TÓTH Péter
Published: October 2023

Bu çalışma, XVII. yüzyılın son çeyreğinde Krallık Macaristanı’nda görülen bir ceza davası üzerinden Macaristan nahiye idaresinde mahkeme sürecini ele almayı amaçlamaktadır. Maktul, 1686 yılının Noel kutlamaları sırasında, Eğri Kalesi’nden yola çıkıp Ónod Kalesi’ne varmak isteyen bir Türk’tür. Mahkeme kaydında ismine, yaşına ve mesleğine dair hiçbir bilgiye rastlanmamaktadır. Yola çıkış amacı Hıristiyanlık inancına geçmek olan maktul, Miskolc kasabasında konakladığı zaman bir grup Macar tarafından kendisinin altın işlemeli kılıcını ele geçirmek gayesiyle öldürülmüştür. Öldürme planını tasarlayan Száraz János, nahiye şûrası tarafından infaz edilirken suç ortağı Borbély György isimli asilzadeye karşı 1687 yılında dava açılmıştır. Mahkeme kaydını önemli kılan hadise, bahsi geçen asilzadenin ihanet suçuyla yargılanmasıdır. Zira isnat edilen bu suç sebebiyle sanık tüm servetini ve hatta canını kaybetme tehlikesiyle karşı karşıyadır.
The Use of Oral Antibiotics After Total Joint Arthroplasty
Authors: Tidd Joshua L. , Pasqualini Ignacio , McConaghy Kara , Higuera Carlos A. , Deren Matthew E. , Visperas Anabelle , Klika Alison K. , Piuzzi Nicolas S.
Published: October 2023

» There is conflicting and insufficient evidence that extended oral antibiotic (EOA) therapy prevents infection in high-risk patients undergoing primary total joint arthroplasty (TJA), limiting recommendation for or against the practice.

» In the case of aseptic revision TJA, the evidence is also conflicting and limited by underlying confounders, preventing recommendation for use of EOA.

» There is fair evidence that use of EOA after debridement antibiotic therapy and implant retention of the prosthesis prolongs infection-free survival, but randomized controlled trials are needed. On the other hand, there is strong evidence that patients undergoing 2-stage revision should receive a period of suppressive oral antibiotics after the second stage.

» The optimal duration of EOA in primary TJA, aseptic revision, and debridement antibiotic therapy and implant retention of the prosthesis is unknown. However, there is strong evidence that 3 months of EOA suppression may be appropriate after reimplantation as part of 2-stage exchange arthroplasty.

» Complications secondary to EOA are reported to be between 0% and 13.7%, yet are inconsistently reported and poorly defined. The risks associated with antibiotic use, including development of antimicrobial resistance, must be weighed against a possible decrease in infection rate.
Autistic students as partners in the design of tailored employability provision
Authors: Coney Keren
Published: October 2023

A recent study of the destinations of graduates found that of all disabled graduates, autistic individuals are least likely to be employed (AGCAS, 2022). These outcomes for autistic people in the UK are widely recognised in literature (Remington and Pellicano, 2019, Vincent, 2020,) and highlight the way in which these individuals are marginalised. This article outlines the participatory action research project conducted at a UK university over the past two years that explored how to provide effective careers and employability support for autistic students. Understanding that it would be important to involve individuals whom this employability support would seek to benefit, a careers practitioner recruited autistic volunteers to act as consultants. With the exception of the final analysis, these autistic student consultants were engaged in all stages of the project, from analysing an initial survey of all autistic students in the university, to co-designing the careers-related programme and evaluating the effectiveness of these activities. This participatory methodology not only provided the careers practitioner with a deeper appreciation of the lived experience of being autistic and real insights into what provision to include in the future, but was also perceived to have an emancipatory impact on some of participants involved, with signs of a ‘ripple effect’ within the university. This article concludes with recommendations for careers practitioners and researchers who are eager to bring about change at their own educational institutions, resulting in more positive employment outcomes for autistic individuals.
VET career pathways for school students living with disability: Working with employers
Authors: Fischer Sarah , Kilpatrick Sue
Published: October 2023

Research has shown that employers and industry are key partners in work-based learning and can hinder or enhance access to vocational education training (VET). Our capabilities approach focus concerns increasing employer understanding of what is involved in engaging in the work-based component of school-based VET for students with disability. It seeks to identify enhancers and barriers to both employer and student participation in work-based learning in workplaces and strategies to address the barriers. Using a qualitative approach, this interpretive research aims to answer the following principal question: How can employers, students, teachers and other influencers of student education and career pathway choice work together to increase opportunities for successful participation of students with disability in the work-based component of school-based VET? Employers and staff at organisations that support/place school-based VET students with disabilities were interviewed and inductive content analysis was used to code interview transcripts. Findings indicate that while communication and relationships are key factors in ensuring successful work-based learning placements, lack of understanding related to the spectrum of disability can be a barrier. Interview participants also identified workplace and policy barriers. Addressing the implications of our research findings will assist in increasing the willingness of employers to engage in work-based learning for school VET students with disability. This shift in practise has the potential to develop the workforce of the region and create greater breadth of opportunities for work-based learning in the community for school VET students with disability, leading to improved employment outcomes for people with disability.
Out of time: (Re)working disabled graduate employability
Authors: Edwards Shona , Sudlow-Haylett Alexandra
Published: October 2023

As interest in disability employment increases across the world following the COVID-19 pandemic, understanding the employability of disabled graduates becomes an imperative for governments, universities and employers alike. This article investigates employability through the lens of the lived experience of disabled graduates, with one author (Alexandra) serving as a case study. Alexandra’s experience in higher education has been defined by living in crip time, a unique disabled experience of time as non-linear. Alexandra’s story describes how surviving within institutions which operate on normative understandings of time as linear, chronological, and inextricably tied to productivity has caused harm to disabled students. Disabled students are made to feel as though they are ‘falling behind time,’ ‘wasting time,’ and ‘losing time,’ resulting in a struggle to ‘catch up time,’ which impacts upon their wellbeing, confidence, and their sense of self. This struggle disadvantages disabled students from spending time building their ‘employability skills’ throughout their degree. As disabled students complete their studies and seek graduate employment, they come into further contact with industry who further compound harm through placement experiences and the graduate hiring process by not accommodating for crip time. This case study poses conventional mentoring programmes as a site in which disabled students such as Alexandra face barriers to engagement. We argue for a co-designed model of accessible, non-hierarchical peer mentoring, where crip time is accommodated and supported. Such accessible mentoring may serve as an effective intervention and an opportunity for disabled students to develop essential employability skills.
Using Natural Gas Liquid for EOR in a Huff-N-Puff Process – A Feasibility Study
Authors: Alinejad Amin , Dehghanpour Hassan
Published: October 2023

This is a feasibility study investigating the application of natural gas liquid (NGL) in a Huff-n-Puff process for enhanced oil recovery from unconventional tight-oil reservoirs. We use a state-of-the-art high-pressure and high-temperature visualization cell to capture real-time NGL-oil interactions throughout the experiment, both in bulk-phase conditions and in the presence of a core sample. We utilize an ultratight Eagle Ford shale sample extracted from horizontal section of a wellbore. The experiments are conducted at a reservoir pressure and temperature of 3,200 psig and 133℃, respectively with NGL being injected at a liquid state. Our findings indicate the notable solubility of NGL in oil, primarily due to NGL's intermediate hydrocarbon components. During the soaking stage, these intermediate hydrocarbon components of oil partition into the NGL, resulting in enhanced solubility of NGL in oil and a subsequent decrease in oil volume. This observation is confirmed by the gradual color change of NGL to amber. We hypothesize that the NGL is spontaneously and forcefully imbibed into the oil-saturated core plug, displacing the oil, resembling a counter-current surfactant imbibition process. However, due to strong solubility of NGL in oil and the active hydrocarbon component's extraction mechanism, the produced oil is dissolved in NGL rather than forming oil droplets on the rock surface. Following the depletion stage, we observe two sequential oil production stages: 1) a prolonged single-phase flow stage until reaching the saturation pressure of the NGL, with total system compressibility as the dominant oil-recovery mechanism and 2) a two-phase flow region with solution-gas drive as the key oil-recovery mechanism. Remarkably, after one cycle of NGL HnP, most of the oil is recovered which surpasses the recovery factors observed in natural gas or CO2 HnP studies.
Pore Surface Roughness Quantification: From 2D to 3D
Authors: Li Yiteng , He Xupeng , Kwak Hyung , Hoteit Hussein
Published: October 2023

Surface roughness is a persistent challenge that may significantly reduce NMR T2 relaxation time, leading to the misinterpretation of formation and fluid properties. Of particular interest to accurately characterizing pore structures from NMR T2 responses, it is critical to define and quantify surface roughness before modeling its impact on NMR T2 relaxation. Some sophisticated microscope techniques can provide accurate surface roughness measurements; however, these methods probe the surface roughness of selected 2D regions on the rock surface, which may not fully represent surface roughness in 3D space.

As the most commonly used 3D imaging technology, micro-computed tomography (micro-CT) digitizes core plugs into voxelized images. The actual surface roughness cannot be visualized as the length scale of surface textures is smaller than the image resolution. However, when modeling NMR T2 relaxation in digitized pore structures, the irregular pore shape increases surface relaxation. From the macroscopic point of view, the irregularity of solid-pore interfaces serves as the visible "roughness" at the given resolution. Thus, in this study, we treat it as surface roughness, and this raises a practical question of how to characterize surface roughness from micro-CT images.

We proposed an image-based pore surface roughness characterization method, called 3D PSR, which utilizes a plurality of 2D cross-sectional images to approximate the surface roughness of a 3D volumetric pore structure. The accuracy and reliability of 3D PSR are influenced by pore morphology, as well as the number and orientation of cross-sectional planes. To resolve these issues, in this study, we upgrade the workflow by directly characterizing pore surface roughness in 3D space, which is named 3D PSR 2.0. The key to the success of 3D PSR 2.0 is calculating spherical harmonic (SH) coefficients to reconstruct the pore surface and then building the reference surface to characterize surface roughness. The proposed workflow consists of five steps, including image segmentation, pore separation and diagnosis, surface reconstruction, roughness evaluation, and roughness parameterization. Numerical results demonstrate the successful application of spherical harmonics for 3D pore surface roughness characterization.
A Focused Community to Enhance Management in Petroleum Engineering: The Management Technical Section (MTS)
Authors: Capello M. A. , Howes C. S. , Kirkham P. , Aguilera R. F. , Nandurdikar N. , Dogulu S. , Swami G. , Botn T.
Published: October 2023

Our industry will see more disruption in the next decade or two, than it has seen in the past century. Our deliverables will change from ensuring reserves additions and production growth, to ensuring we generate returns on capital greater than the cost of capital, lowering our greenhouse gas footprint, focusing on sustainability and incorporating cross-sectoral innovation. The Management Technical Section (MTS) addresses SPE member and industry needs related to the Management discipline with a taxonomy, early wins, and plans to benefit its more than 10,000 members.

An SPE Management Workgroup was formed to ensure proper coverage in event programming and publications for Management topics without a designated Management Technical Director. The Workgroup produced a roadmap that was transformed into a proposal for a new technical section of SPE, the MTS. They identified opportunities for the MTS to collaborate with other SPE disciplines and standing committees where the content overlaps.

The taxonomy of the MTS includes:

Asset and Portfolio Management Risk Management and Decision-Making Strategic Planning and Management Energy Economics Professionalism, Training and Education

With thousands of members declaring an interest in "management" as either their primary or secondary preferred discipline, the new MTS fills a gap in SPE to enable a deep dive into variety of management topics, some of which were previously addressed in several technical disciplines, but that merit dedicated attention and development.

The MTS aims to advance subjects pertinent to management in oil and gas, including pivotal topics such as ethics, energy transition, and field development. Early wins accomplished in the first year of activities include the launching of the SPE MTS Connect page website with high traffic and engagement ratios. The delivery of webinars, workshops, and activities are designed to raise awareness about the MTS and its taxonomy, and to engage SPE members in dialogue. MTS plans include panels at SPE conferences, the delivery of live sessions, discussion groups for the community, and the publication of materials in the community website library.

The interest in belonging to the MTS became apparent by the growth in the first months of existence, increasing by approximately 14.5% more affiliations, totaling more than 10,000 professional members (from 10,845 June 2022 to 12,419 by October 2022).

As global upstream, midstream, and downstream companies face new challenges, Managers’ face new responsibilities as Agents of Shareholders in addition to new expectations from other stakeholders. The MTS will promote holistic thinking to improve performance, share effective risk management techniques, highlight new market opportunities, and leverage our global professional network to drive change.