bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants
Authors: Faccioli Lanuza A. P. , Cetin Zeliha , Kocas-Kilicarslan Zehra N. , Ortiz Kimberly , Sun Yiyue , Hu Zhiping , Kurihara Takeshi , Tafaleng Edgar N. , Florentino Rodrigo M. , Wang Zi , Xia Mengying , Miedel Mark T. , Taylor D. Lansing , Behari Jaideep , Ostrowska Alina , Constantine Robert , Li Albert , Soto-Gutierrez Alejandro
Published: August 2023

Metabolic-dysfunction-associated steatotic liver disease (MASLD), which affects 30 million people in the US and is anticipated to reach over 100 million by 2030, places a significant financial strain on the healthcare system. There is presently no FDA-approved treatment for MASLD despite its public health significance and financial burden. Understanding the connection between point mutations, liver enzymes, and MASLD is important for comprehending drug toxicity in healthy or diseased individuals. Multiple genetic variations have been linked to MASLD susceptibility through genome-wide association studies (GWAS), either increasing MASLD risk or protecting against it, such as PNPLA3 rs738409, MBOAT7 rs641738, GCKR rs780094, HSD17B13 rs72613567, and MTARC1 rs2642438. As the impact of genetic variants on the levels of drug-metabolizing cytochrome P450 (CYP) enzymes in human hepatocytes has not been thoroughly investigated, this study aims to describe the analysis of metabolic functions for selected phase I and phase II liver enzymes in human hepatocytes. For this purpose, fresh isolated primary hepatocytes were obtained from healthy liver donors (n = 126), and liquid chromatography–mass spectrometry (LC–MS) was performed. For the cohorts, participants were classified into minor homozygotes and nonminor homozygotes (major homozygotes + heterozygotes) for five gene polymorphisms. For phase I liver enzymes, we found a significant difference in the activity of CYP1A2 in human hepatocytes carrying MBOAT7 (p = 0.011) and of CYP2C8 in human hepatocytes carrying PNPLA3 (p = 0.004). It was also observed that the activity of CYP2C9 was significantly lower in human hepatocytes carrying HSD17B13 (p = 0.001) minor homozygous compared to nonminor homozygous. No significant difference in activity of CYP2E1, CYP2C8, CYP2D6, CYP2E1, CYP3A4, ECOD, FMO, MAO, AO, and CES2 and in any of the phase II liver enzymes between human hepatocytes carrying genetic variants for PNPLA3 rs738409, MBOAT7 rs641738, GCKR rs780094, HSD17B13 rs72613567, and MTARC1 rs2642438 were observed. These findings offer a preliminary assessment of the influence of genetic variations on drug-metabolizing cytochrome P450 (CYP) enzymes in healthy human hepatocytes, which may be useful for future drug discovery investigations.
Exploring CVD Method for Synthesizing Carbon–Carbon Composites as Materials to Contact with Nerve Tissue
Authors: Fraczek-Szczypta Aneta , Kondracka Natalia , Zambrzycki Marcel , Gubernat Maciej , Czaja Pawel , Pawlyta Miroslawa , Jelen Piotr , Wielowski Ryszard , Jantas Danuta
Published: August 2023

The main purpose of these studies was to obtain carbon–carbon composites with a core built of carbon fibers and a matrix in the form of pyrolytic carbon (PyC), obtained by using the chemical vapor deposition (CVD) method with direct electrical heating of a bundle of carbon fibers as a potential electrode material for nerve tissue stimulation. The methods used for the synthesis of PyC proposed in this paper allow us, with the appropriate selection of parameters, to obtain reproducible composites in the form of rods with diameters of about 300 µm in 120 s (CF_PyC_120). To evaluate the materials, various methods such as scanning electron microscopy (SEM), scanning transmission electron microscope (STEM), high-resolution transmission electron microscopy (HRTEM), selected area electron diffraction (SAED), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), and tensiometer techniques were used to study their microstructural, structural, chemical composition, surface morphology, and surface wettability. Assessing their applicability for contact with nervous tissue cells, the evaluation of cytotoxicity and biocompatibility using the SH-SY5Y human neuroblastoma cell line was performed. Viability and cytotoxicity tests (WST-1 and LDH release) along with cell morphology examination demonstrated that the CF_PyC_120 composites showed high biocompatibility compared to the reference sample (Pt wire), and the best adhesion of cells to the surface among all tested materials.
In Vitro Resistance of Natural Molars vs. Additive-Manufactured Simulators Treated with Pulpotomy and Endocrown
Authors: Munoz-Sanchez Marie-Laure , Gravier Alexis , Francois Olivier , Nicolas Emmanuel , Hennequin Martine , Decerle Nicolas
Published: August 2023

Endocrowns are designed to restore endodontically treated teeth with root canal treatment (Rct). Recently, endocrowns were proposed for teeth treated with full pulpotomy (FP). No data exist on in vitro evaluations for this combination. This study aimed to evaluate the mechanical behavior of pulpotomy-treated teeth with endocrowns according to different protocols for preparation design and materials and to assess whether 3D-printed resin simulators could be a reliable alternative for human teeth during in vitro strength tests. One hundred and ten extracted natural molars were randomized into 11 groups according to the type of endodontic treatment, the material used, and the design of peripheric preparation. One hundred and ten resin simulators were separated similarly. The samples were embedded in epoxy resin blocks before being subjected to oblique compressive load until failure. For natural teeth, the variance analysis separated two homogeneous groups, one regrouping the endodontically treated or pulpotomy-treated teeth without coronal restoration and the other one regrouping all the other samples, i.e., the untreated teeth (positive controls) and the treated and restored teeth. The strength resistance was lower for the resin simulators than for natural teeth in all groups. Within the limit of this study, strength resistance is not the most important criterion for choosing the type of material, preparation, or endodontic treatment for endocrowns. Resin simulators are not efficient for in vitro strength studies.
A New Lighting System for Surgical Vision Optimization in Barbed Pharyngoplasty for OSA
Authors: Sabatino Lorenzo , Moffa Antonio , Iafrati Francesco , Di Giovanni Simone , De Benedetto Luigi , Giorgi Lucrezia , Baptista Peter , Vicini Claudio , De Vito Andrea , Casale Manuele
Published: August 2023

Obstructive sleep apnea (OSA) surgery is now a viable solution in selected patients and the “remodeling” palatopharyngeal surgery is the most common one. Recently, it has become less invasive with the introduction of barbed sutures (BS). An optimization of surgical techniques is represented by barbed pharyngoplasty (BP), which requires surgical precision and needs efficient and precise oropharyngeal visualization. Consequently, the lighting system is of pivotal importance in BP. The aim of this work is to describe the first experience on the use of a new lighting system, called KLAROTM in BP for OSA. We evaluated the KLARO™ system in 15 consecutives BP for OSA in comparison with conventional headlamp illumination. The visualization of palatopharyngeal muscle in the bottom of the tonsillar fossa, entry and exit needle, such as needle tip, were statistically better with KLAROTM than headlamp illumination for both the surgeon and resident (p < 0.05). No significant differences for the visualization of the posterior pharyngeal wall and uvula were reported. The KLAROTM lighting system allows a satisfied illumination of oral cavity and oropharynx in the majority of cases. We encourage the use of KLAROTM not only in BP for OSA, but in all oral and pharyngeal surgeries, including tonsillectomy and oncological surgery.
High-Salt Diet Exacerbates H. pylori Infection and Increases Gastric Cancer Risks
Authors: Balendra Vyshnavy , Amoroso Chiara , Galassi Barbara , Esposto Josephine , Bareggi Claudia , Luu Jennie , Scaramella Lucia , Ghidini Michele
Published: August 2023

Gastric cancer ranks as the fifth-leading contributor to global cancer incidence and the fourth-highest in terms of cancer-related mortality. Helicobacter pylori (H. pylori) infection leads to inflammation and ulceration, atrophic and chronic gastritis, and eventually, increases the risk of developing gastric adenocarcinoma. In this paper, we delve into the combined impact of a high-salt diet (HSD) and concurrent H. pylori infection, which act as predisposing factors for gastric malignancy. A multitude of mechanisms come into play, fostering the development of gastric adenocarcinoma due to the synergy between an HSD and H. pylori colonization. These encompass the disruption of mucosal barriers, cellular integrity, modulation of H. pylori gene expression, oxidative stress induction, and provocation of inflammatory responses. On the whole, gastric cancer patients were reported to have a higher median sodium intake with respect to healthy controls. H. pylori infection constitutes an additional risk factor, with a particular impact on the population with the highest daily sodium intake. Consequently, drawing from epidemiological discoveries, substantial evidence suggests that diminishing salt intake and employing antibacterial therapeutics could potentially lower the susceptibility to gastric cancer among individuals.
Skinfold Thickness as a Cardiometabolic Risk Predictor in Sedentary and Active Adult Populations
Authors: González-Torres Sughey , Anaya-Esparza Luis Miguel , Trigueros del Valle Gabriel Fermín , Rivera-León Edgar Alfonso , Villagrán Zuamí , Sánchez-Enríquez Sergio
Published: August 2023

Studies report that increased body fat can lead to health risks for individuals. However, some methods used for analyzing adiposity did not identify its distribution in the human body because they are typically measured using bioimpedance scales. This study aims to associate the presence of cardiometabolic risk factors in sedentary and active adult populations through anthropometric methods based on skinfold thickness measurements. A cross-sectional study was conducted on 946 adults aged between 18 and 79 years with prior informed consent. Clinical, anthropometric, and biochemical parameters, as well as some cardiometabolic risk factors, were evaluated. Almost half of the population (45.1%; n = 427) is sedentary. A significant association was found between the sum of the skinfolds (bicipital, tricipital, subscapular, and suprailiac) and the cardiometabolic risk factors evaluated, highlighting the cardiovascular risk associated with abdominal obesity, risk of insulin resistance, as well as the development of hyperglycemia, and hypertriglyceridemia. The bicipital fold was thicker (19.67 mm) in the population with a sedentary lifestyle than in the physically active population (18.30 mm). Furthermore, the skinfolds that predict higher metabolic risks were suprailiac and subscapular in sedentary and active populations. Thus, these skinfold measurements could be considered in assessing the adult population for early cardiometabolic risk detection, even in healthy and physically active people.
Airway Management: The Current Role of Videolaryngoscopy
Authors: Saul Sophie A. , Ward Patrick A. , McNarry Alistair F.
Published: August 2023

Airway management is usually an uncomplicated and safe intervention; however, when problems arise with the primary airway technique, the clinical situation can rapidly deteriorate, resulting in significant patient harm. Videolaryngoscopy has been shown to improve patient outcomes when compared with direct laryngoscopy, including improved first-pass success at tracheal intubation, reduced difficult laryngeal views, reduced oxygen desaturation, reduced airway trauma, and improved recognition of oesophageal intubation. The shared view that videolaryngoscopy affords may also facilitate superior teaching, training, and multidisciplinary team performance. As such, its recommended role in airway management has evolved from occasional use as a rescue device (when direct laryngoscopy fails) to a first-intention technique that should be incorporated into routine clinical practice, and this is reflected in recently updated guidelines from a number of international airway societies. However, currently, overall videolaryngoscopy usage is not commensurate with its now widespread availability. A number of factors exist that may be preventing its full adoption, including perceived financial costs, inadequacy of education and training, challenges in achieving deliverable decontamination processes, concerns over sustainability, fears over “de-skilling” at direct laryngoscopy, and perceived limitations of videolaryngoscopes. This article reviews the most up-to-date evidence supporting videolaryngoscopy, explores its current scope of utilisation (including specialist techniques), the potential barriers preventing its full adoption, and areas for future advancement and research.
Optimising Hollow-Structured Silicon Nanoparticles for Lithium-Ion Batteries
Authors: Yue Chenghao , Liu Yao , Guan Shaoliang , Fereydooni Alireza , Zeng Yuexi , Wei Zhijie , Wang Yonggang , Chao Yimin
Published: August 2023

Silicon has been proven to be one of the most promising anode materials for the next generation of lithium-ion batteries for application in batteries, the Si anode should have high capacity and must be industrially scalable. In this study, we designed and synthesised a hollow structure to meet these requirements. All the processes were carried out without special equipment. The Si nanoparticles that are commercially available were used as the core sealed inside a TiO2 shell, with rationally designed void space between the particles and shell. The Si@TiO2 were characterised using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). The optimised hollow-structured silicon nanoparticles, when used as the anode in a lithium-ion battery, exhibited a high reversible specific capacity over 630 mAhg−1, much higher than the 370 mAhg−1 from the commercial graphite anodes. This excellent electrochemical property of the nanoparticles could be attributed to their optimised phase and unique hollow nanostructure.
An Experimental Study on the Properties of Concrete and Fiber-Reinforced Concrete in Rigid Pavements
Authors: Kos Željko , Kroviakov Sergii , Mishutin Andrii , Poltorapavlov Andrii
Published: August 2023

The complex effect of the amount of cement, polypropylene fiber (the fiber length was 39 mm, and the diameter was 0.45 mm), and polycarboxylate superplasticizer on concrete properties for rigid pavement was determined using the methods of experiment planning and experimental–statistical modeling. The fluidity of all the mixtures was S1. The W/C of the mixtures depended on the composition of the concrete and variable from 0.32 to 0.46. It was found that, by increasing the amount of superplasticizer from 1% to 1.8–2%, the compressive strength of concrete increased by 4.5–6 MPa after 3 days and by 7–9 MPa after 28 days. The flexural strength in this case increased by 0.6–0.9 MPa. The use of polypropylene fiber in the amount of 1.5–1.8 kg/m3 increased the compressive strength of concrete by an average of 3 MPa, increased the flexural strength by 0.5–0.6 MPa, reduced the abrasion capacity by 9–14%, and increased the frost resistance by up to 50 cycles. When using a rational amount of superplasticizer and fiber, the compressive strength of concrete, even with a minimum cement amount of 350 kg/m3, was at least 65 MPa, its flexural strength was at least 6 MPa, its frost resistance was F200, and its abrasion capacity was not more than 0.30 g/cm2. Concrete with such properties can be used for roadways of any type. Low abrasion capacity and high frost resistance provide the necessary durability of concrete for rigid pavement during operation.
Ultrasonic-Assisted Surface Finishing of STAVAX Mold Steel Using Lab-Made Polishing Balls on a 5-Axis CNC Machining Center
Authors: Shiou Fang-Jung , Pan Jian-Nan , Ding Zhao-Li , Lin Sun-Peng
Published: August 2023

The inconvenience of conventional wool ball polishing is that the surface finishing process should be equipped with a slurry container. The main objective of this research is to develop an ultrasonic-assisted surface finishing process for STAVAX mold steel on a 5-axis CNC machining center, by using new lab-made rubber polishing balls containing the abrasive aluminum oxide instead of the traditional wool ball polishing. In total, five types (type A to type E) of new rubber-matrixed polishing balls with a composite of nitrile butadiene rubber (NBR), an abrasive of aluminum oxide, and an additive of silicon dioxide have been developed. The performance of the composites with different grain sizes (0.05 μm to 3 μm) and concentrations of the abrasive of aluminum oxide have been investigated. The effects of multiple polishing passes on the surface roughness improvement for the lab-made polishing balls have also been investigated in this study. A surface roughness of Ra 0.027 μm on average was achieved by using the multiple polishing process of E-C-B-A. The volumetric wear of the lab-made polishing balls, using ultrasonic vibration-assisted polishing, can be improved from about 12.64% (type A) to 65.48% (type E) compared with the non-vibration-assisted polishing. The suitable combination of the ultrasonic vibration-assisted polishing parameters were an amplitude of 10 μm, a frequency of 23 kHz, a spindle speed of 5000 rpm, a feed rate of 60 mm/min, a stepover of 20 μm, a penetration depth of 180 μm, and a polishing pass of E-C-B-A, based on the experimental results. The surface roughness improvement on a test carrier with a saddle surface has also been presented by using the ultrasonic vibration-assisted polishing with the lab-made polishing balls.
Two-Dimensional Microstructure-Based Model for Evaluating the Permeability Coefficient of Heterogeneous Construction Materials
Authors: Chen Jiaqi , Yu Shujun , Huang Wei , Wang Hao
Published: August 2023

The permeability coefficient of construction materials plays a crucial role in engineering quality and durability. In this study, a microstructure model based on real aggregate shape and digital image technology is proposed to predict the permeability coefficient of concrete. A two-dimensional, three-component finite element model of cement concrete was established considering the interfacial transition zone (ITZ) between aggregate and mortar. The permeability coefficient prediction model was developed by the finite element method. The accuracy of the model was verified by experimental data, and the influence of the water−cement ratio on the permeability coefficient of concrete was analyzed. The results show that this method has good prediction accuracy with a relative error of 1.73%. According to the verified model, the influences of aggregate content, aggregate characteristics, aggregate location, ITZ thickness, and other factors on the permeability of concrete were explored. The higher the water−cement ratio, the higher the permeability coefficient. With the increase in aggregate content, the permeability coefficient decreases. Aggregate permeability has a significant influence on the effective permeability coefficient of concrete within a certain range. The greater the roundness of aggregate, the greater the permeability of concrete. On the contrary, the larger aggregate size causes lower permeability. The permeability coefficient of concrete with segregation is lower than that with uniform distribution. At the same time, the permeability increases with the increase of ITZ thickness.
Large-Scale Fabrication of SiC-TiC@C Powders via Modified Molten Salt Shielding Synthesis Technique and Their Effect on the Properties of Al2O3-MgO Castables
Authors: Li Yong , Yin Yicheng , Chen Jing , Kang Xiaoxu , Kang Shihao , Ma Haoxuan , Zhang Shaowei , Jia Quanli
Published: August 2023

Graphite flakes are commonly used to fabricate carbon-based refractories owing to their superior properties, including better corrosion resistance and thermal shock resistance (TSR); unfortunately, their insufficient water-wettability has remarkably hindered their application in castables. Aiming to enhance their water-wettability, a facile and low-cost technique for fabricating carbides coated in graphite was proposed in this work. Firstly, SiC-TiC coated graphite (SiC-TiC@C) powders were prepared via modified molten salt shielding synthesis in an air atmosphere using graphite flake, Si and Ti powders as raw materials and NaCl-KCl as the molten salt shielding medium. Water-wettability and oxidation resistance of SiC-TiC@C powders were significantly improved. Compared to the Al2O3-MgO castables with graphite flakes, the water demand of the castables with SiC-TiC@C was noticeably decreased from 6.85% to 4.89%, thereby decreasing the apparent porosity of the castables with 5% SiC-TiC@C (from 20.3% to 13%), enhancing the cold strength, hot strength and oxidation resistance of the castables. Such enhancements are ascribed to continuous and crack-free SiC-TiC coatings on graphite surfaces ensuring that the castables have outstanding properties.
Human Bone-Marrow-Derived Stem-Cell-Seeded 3D Chitosan–Gelatin–Genipin Scaffolds Show Enhanced Extracellular Matrix Mineralization When Cultured under a Perfusion Flow in Osteogenic Medium
Authors: Boretti Gabriele , Giordano Emanuele , Ionita Mariana , Vlasceanu George Mihail , Sigurjónsson Ólafur Eysteinn , Gargiulo Paolo , Lovecchio Joseph
Published: August 2023

Tissue-engineered bone tissue grafts are a promising alternative to the more conventional use of natural donor bone grafts. However, choosing an appropriate biomaterial/scaffold to sustain cell survival, proliferation, and differentiation in a 3D environment remains one of the most critical issues in this domain. Recently, chitosan/gelatin/genipin (CGG) hybrid scaffolds have been proven as a more suitable environment to induce osteogenic commitment in undifferentiated cells when doped with graphene oxide (GO). Some concern is, however, raised towards the use of graphene and graphene-related material in medical applications. The purpose of this work was thus to check if the osteogenic potential of CGG scaffolds without added GO could be increased by improving the medium diffusion in a 3D culture of differentiating cells. To this aim, the level of extracellular matrix (ECM) mineralization was evaluated in human bone-marrow-derived stem cell (hBMSC)-seeded 3D CGG scaffolds upon culture under a perfusion flow in a dedicated custom-made bioreactor system. One week after initiating dynamic culture, histological/histochemical evaluations of CGG scaffolds were carried out to analyze the early osteogenic commitment of the culture. The analyses show the enhanced ECM mineralization of the 3D perfused culture compared to the static counterpart. The results of this investigation reveal a new perspective on more efficient clinical applications of CGG scaffolds without added GO.
Study on the Migration Behaviors of Magnesium Oxysulfate Nano-Whiskers in Polypropylene Composites with Surface Modification
Authors: Won Jong Sung , Park Jeong Jin , Kang Eun Hye , Jeon Min Hong , Kwon Miyeon , Lee Seung Goo
Published: August 2023

In this study, surface modification aimed to enhance the compatibility between a hydrophilic inorganic filler and polypropylene (PP) matrix using hydrophobic treatment. Lauric acid, butyl acrylate, and maleic anhydride were employed to modify the filler surface. After treatment, inorganic filler/PP composites were produced using melt-mixing and extrusion–injection molding processes. The study focused on investigating compatibility and migration behavior between the filler and matrix. The findings indicated that hydrophobic modification, specifically with butyl acrylate and maleic anhydride, improved migration issues in nano-whisker, while maintaining favorable mechanical properties even under accelerated thermal aging. However, excessive hydrophobicity induced by superhydrophobic treatment using lauric acid led to reduced compatibility with the matrix, compromising its effectiveness. Consequently, the study revealed the potential of surface modification to enhance interfacial properties and mitigate migration concerns in PP composites for automotive applications.
Photocatalytic Activity of N-Doped ZrO2 Thin Films Determined by Direct and Indirect Irradiation
Authors: Mita Carmen , Cornei Nicoleta , Frenti Mariana , Bulai Georgiana , Dobromir Marius , Tiron Vasile , Doroshkevich Aleksandr S. , Mardare Diana
Published: August 2023

In this paper, we investigate the decomposition of a toxic organic compound, Rhodamine B, by the photocatalytic activities of undoped and nitrogen-doped ZrO2 thin films, deposited using the HiPIMS technique. The investigation was performed in the presence and in the absence of H2O2, for two types of experimental arrangements: the irradiation of the films, followed by dipping them in the Rhodamine B solutions, and the irradiation of the films dipped in the solution. The two situations were named “direct irradiation” and “indirect irradiation”, respectively. Methods like XRD, AFM, XPS, DRS, water/film surface contact angle, and spectrophotometry were used to obtain information on the films’ structure, surface morphology, elemental composition of the films surface, optical band gap, hydrophilicity, and photocatalytic activity, respectively. All these properties were described and correlated. By N-doping ZrO2, the films become absorbent in the visible domain, so that the solar light could be efficiently used; the films’ hydrophilic properties improve, which is an important fact in self-cleaning applications; and the films’ photocatalytic activity for the decomposition of Rhodamine B becomes better. The addition of hydrogen peroxide acted as an inhibitor for all systems and not as an accelerator of the photocatalytic reactions as expected.
Potential Role of GGBS and ACBFS Blast Furnace Slag at 90 Days for Application in Rigid Concrete Pavements
Authors: Nicula Liliana Maria , Manea Daniela Lucia , Simedru Dorina , Cadar Oana , Dragomir Mihai Liviu , Ardelean Ioan , Corbu Ofelia
Published: August 2023

Incorporating blast furnace slag into the composition of paving concrete can be one of the cost-effective ways to completely eliminate by-products from the pig iron production process (approximately 70% granulated slag and 30% air-cooled slag). The possibility to reintroduce blast furnace slag back into the life cycle will provide significant support to current environmental concerns and the clearance of tailings landfills. Especially in recent years, granulated and ground blast furnace slag (GGBS) as a substitute for cement and air-cooled blast furnace slag (ACBFS) aggregates as a substitute for natural aggregates in the composition of concretes have been studied by many researchers. But concrete compositions with large amounts of incorporated blast furnace slag affect the mechanical and durability properties through the interaction between the slag, cement and water depending on the curing times. This study focuses on identifying the optimal proportions of GGBS as a supplementary cementitious material (SCM) and ACBFS aggregates as a substitute to natural sand such that the performance at 90 days of curing the concrete is similar to that of the control concrete. In addition, to minimize the costs associated with grinding GGBS, the hydration activity index (HAI) of the GGBS, the surface morphology, and the mineral components were analyzed via X-ray diffraction, scanning electron microscopy (SEM), energy dispersive spectrometry (EDX), and nuclear magnetic resonance relaxometry (NMR). The flexural strength, the basic mechanical property of road concretes, increased from 28 to 90 days by 20.72% and 20.26% for the slag concrete but by 18.58% for the reference concrete. The composite with 15% GGBS and 25% ACBFS achieved results similar to the reference concrete at 90 days; therefore, they are considered optimal percentages to replace cement and natural sand in ecological pavement concretes. The HAI of the slag powder with a specific surface area equivalent to that of Portland cement fell into strength class 80 at the age of 28 days, but at the age of 90 days, the strength class was 100. The results of this research present three important benefits: the first is the protection of the environment through the recycling of two steel industry wastes that complies with European circular economy regulations, and the second is linked to the consequent savings in the disposal costs associated with wastefully occupied warehouses and the savings in slag grinding.
Photo- and Thermocatalytic CO2 Methanation: A Comparison of Ni/Al2O3 and Ni–Ce Hydrotalcite-Derived Materials under UV and Visible Light
Authors: Canales Rafael , Barrio Victoria Laura
Published: August 2023

Catalysts derived from Ni/Al/Mg/Ce hydrotalcite were prepared via a co-precipitation method, varying the Ce/Al atomic ratio. All of the catalytic systems thus prepared were tested for CO2 methanation under dark and photocatalytic conditions (visible and ultraviolet) under continuous flow with the light intensity set to 2.4 W cm−2. The substitution of Al by Ce formed a solid solution, generating oxygen vacancies and Ce3+/Ce4+ ions that helped shift the dissociation of CO2 towards the production of CH4, thus enhancing the activity of methanation, especially at lower temperatures (<523 K) and with visible light at temperatures where other catalysts were inactive. Additionally, for comparison purposes, Ni/Al2O3-based catalysts prepared via wetness impregnation were synthesized with different Ni loadings. Analytical techniques were used for the characterization of the systems. The best results in terms of activity were as follows: Hydrotalcite with Ce promoter > Hydrotalcite without Ce promoter > 25Ni/Al2O3 > 13Ni/Al2O3. Hydrotalcite, with a Ce/Al atomic ratio of 0.22 and a Ni content of 23 wt%, produced 7.74 mmol CH4 min−1·gcat at 473 K under visible light. Moreover, this catalyst exhibited stable photocatalytic activity during a 24 h reaction time with a CO2 conversion rate of 65% and CH4 selectivity of >98% at 523 K. This photocatalytic Sabatier enhancement achieved activity at lower temperatures than those reported in previous publications.
Preparation of UV Debonding Acrylate Adhesives by a Postgrafting Reaction
Authors: Wang Juan , Dong Zhikai , Chen Jingwen , Chen Shuangjun
Published: August 2023

UV debonding acrylate adhesive (UDAA) plays a crucial role in the semiconductor industry, where its excellent adhesion is required to ensure the stability of silicon wafers and leave no residue on the surface after UV irradiation. The necessary UV debonding is achieved through the formation of rigid networks by the reactions of all the vinyl groups in the system. Acrylate copolymers with vinyl groups are typically obtained by the grafting reaction of isocyanate with a side-chain hydroxyl comonomer. However, these grafting reactions easily fail due to early cross-link formation. In this study, we illustrate a straightforward method for preparing UDAA by conducting a postgrafting reaction after one-step mixing of isocyanate functional monomer (IPDI-H) and hydroxyl acrylate copolymers (BA-H), thereby skipping the abovementioned vinyl grafting process. The chemical structures of the synthesized IPDI-H and BA-H were confirmed using Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR) analysis. Gel permeation chromatography (GPC) was employed to determine their molecular weights, while differential scanning calorimetry (DSC) was used to determine their glass transition temperatures. The postgrafting reactions successfully introduced vinyl groups onto the polyacrylate copolymer chains, resulting in high bonding strength during use and a significant decrease in peeling strength after UV irradiation. Rheological methods, including the three-interval thixotropy test (3ITT) and tack test modes, were employed to characterize a series of acrylate UV debonding adhesives. The recovery percentage of the storage modulus in the 3ITT mode indicated that a 0.6 wt% isocyanate curing agent made the UV debonding adhesives resistant to deformation. From the maximum normal force in the tack test mode, it was found that UDAA with 10 wt% PETA monomer and 30 wt% C5 tackifying resin exhibited excellent combined adhesion and debonding properties, which were further confirmed by peel strength tests. Microscope images of the wafer surfaces after removing the adhesive tapes demonstrated the excellent UV debonding properties achieved after 40 s of UV irradiation through the postgrafting reaction. The prepared UDAA has excellent properties; the peel strength can reach 15 N/25 mm before UV irradiation and can be reduced to 0.5 N/25 mm after ultraviolet irradiation. This research establishes a comprehensive method for understanding and applying UDAA in various applications.
Ultra-Wideband Electromagnetic Composite Absorber Based on Pixelated Metasurface with Optimization Algorithm
Authors: Lee Changhyeong , Kim Kichul , Park Pyoungwon , Jang Yunseok , Jo Jeongdai , Choi Taein , Lee Hakjoo
Published: August 2023

An ultra-wideband electromagnetic (EM) absorber is proposed. The proposed absorber consists of two thin metasurfaces, four dielectric layers, a glass fiber reinforced polymer (GFRP), and a carbon fiber reinforced polymer (CFRP) which works as a conductive reflector. The thin metasurfaces are accomplished with 1-bit pixelated patterns and optimized by a genetic algorithm. Composite materials of GFRP and CFRP are incorporated to improve the durability of the proposed absorber. From the full-wave simulation, more than 90% absorption rate bandwidth is computed from 2.2 to 18 GHz such that the fractional bandwidth is about 156% for the incidence angles from 0° to 30°. Absorptivity is measured using the Naval Research Laboratory (NRL) arch method in an EM anechoic environment. It was shown that the measured results correlated with the simulated results. In addition, the proposed absorber underwent high temperature and humidity tests under military environment test conditions in order to investigate its durability.
Asymmetric Distribution of Plasmalogens and Their Roles—A Mini Review
Authors: Honsho Masanori , Fujiki Yukio
Published: August 2023

Plasmalogens are a unique family of cellular glycerophospholipids that contain a vinyl-ether bond. The synthesis of plasmalogens is initiated in peroxisomes and completed in the endoplasmic reticulum. Plasmalogens are transported to the post-Golgi compartment, including endosomes and plasma membranes, in a manner dependent on ATP, but not vesicular transport. Plasmalogens are preferentially localized in the inner leaflet of the plasma membrane in a manner dependent on P4-type ATPase ATP8B2, that associates with the CDC50 subunit. Plasmalogen biosynthesis is spatiotemporally regulated by a feedback mechanism that senses the amount of plasmalogens in the inner leaflet of the plasma membrane and controls the stability of fatty acyl-CoA reductase 1 (FAR1), the rate-limiting enzyme for plasmalogen biosynthesis. The physiological consequences of such asymmetric localization and homeostasis of plasmalogens are discussed in this review.
Evolution of Recrystallization Texture in A286 Iron-Based Superalloy Thin Plates Rolled via Various Routes
Authors: Zhang Renjie , Zhang Chi , Wang Zeyu , Liu Jinlong
Published: August 2023

The A286 iron-based superalloy has wide-ranging applications in replacing expensive nickel-based and cobalt-based superalloy to manufacture the turbine disk as well as the pipelines and valves of the fourth-generation supercritical water reactor (SCWR) working below 650 °C. The recrystallization texture importantly affects the mechanical properties and oxidation resistance of superalloys. However, very few investigations are available on the recrystallisation texture of A286 alloy. The current work reports the texture of A286 alloy fabrication using various rolling routes, including one-stage cold rolling with the rolling rates of 83% (Route I) and 91% (Route II), and two-stage cold rolling with the rolling rate of 83% + 50% (Route III). Route III is preferentially recommended to manufacture A286 alloy thin plates due to the obviously reduced work hardening as well as the weakened recrystallization texture and anisotropy; moreover, compared with other routes, the recrystallized grain size of Route III did not significantly coarsen. We also revealed the mechanism for the effect of cold rolling textures on the final recrystallization texture and the role of the deformation twin in {110} <115> grain. In this study, recrystallization texture develops through two independent mechanisms related to different deformation microstructures, including the recrystallization texture inherited from deformation texture and the recrystallization texture depended on deformation twins.
Study on Joining for Thin-Walled Aluminum Alloy/Steel Tubes by Electromagnetic Flanging Process
Authors: Chen Chang , Zhao Yujia , Wang Dayong , Cui Junjia , Li Guangyao , Jiang Hao
Published: August 2023

A structure for joining thin-walled 6061-T6 aluminum alloy tube (outer tube) and Q195 steel tube (inner tube) by electromagnetic flanging process was proposed. The formation process, mechanical properties, failure modes, and morphology of the joint were investigated. The results showed that the outer tube impacted the inner tube, the flanges of the prefabricated holes on the outer tube were embedded into the prefabricated holes of the inner tube under the action of Lorentz force, and thus the mechanical locking joint was obtained. There were two tensile failure modes for the joints: Pull-out and fracture. Specifically, when the discharge energy was relatively high, the failure mode changed from pull-out to fracture. Combining the results of tensile tests and morphology observations, the maximum loads of the joints increased with the discharge energy. However, excessive discharge energy would lead to the brittle fracture of the inner tube, which was not beneficial to the service. Better discharge energy and the maximum load of the joint at this discharge energy were obtained.
Biomass-Derived Carbon-Based Electrodes for Electrochemical Sensing: A Review
Authors: Onfray Christian , Thiam Abdoulaye
Published: August 2023

The diverse composition of biomass waste, with its varied chemical compounds of origin, holds substantial potential in developing low-cost carbon-based materials for electrochemical sensing applications across a wide range of compounds, including pharmaceuticals, dyes, and heavy metals. This review highlights the latest developments and explores the potential of these sustainable electrodes in electrochemical sensing. Using biomass sources, these electrodes offer a renewable and cost-effective route to fabricate carbon-based sensors. The carbonization process yields highly porous materials with large surface areas, providing a wide variety of functional groups and abundant active sites for analyte adsorption, thereby enhancing sensor sensitivity. The review classifies, summarizes, and analyses different treatments and synthesis of biomass-derived carbon materials from different sources, such as herbaceous, wood, animal and human wastes, and aquatic and industrial waste, used for the construction of electrochemical sensors over the last five years. Moreover, this review highlights various aspects including the source, synthesis parameters, strategies for improving their sensing activity, morphology, structure, and functional group contributions. Overall, this comprehensive review sheds light on the immense potential of biomass-derived carbon-based electrodes, encouraging further research to optimize their properties and advance their integration into practical electrochemical sensing devices.
Fast Hologram Calculation Method Based on Wavefront Precise Diffraction
Authors: Wang Zimu , Li Yilong , Tang Zhenyan , Li Zhaosong , Wang Di
Published: August 2023

In this paper, a fast hologram calculation method based on wavefront precise diffraction is proposed. By analyzing the diffraction characteristics of the object point on the 3D object, the effective viewing area of the reproduced image is analyzed. Based on the effective viewing area, the effective hologram size of the object point is obtained, and then the accurate diffraction calculation from the object point to the wavefront recording plane (WRP) is performed. By calculating all the object points on the recorded object, the optimized WRP of the whole 3D object can be obtained. The final hologram is obtained by calculating the diffraction light field from the WRP to the holographic plane. Compared with the traditional method, the proposed method can improve the calculation speed by more than 55%, while the image quality of the holographic 3D display is not affected. The proposed calculation method provides an idea for fast calculation of holograms and is expected to contribute to the development of dynamic holographic displays.
Research on Fractal Characteristics and Influencing Factors of Pore-Throats in Tight Sandstone Reservoirs: A Case Study of Chang 6 of the Upper Triassic Yanchang Formation in Huaqing Area, Ordos Basin, China
Authors: Nan Fanchi , Lin Liangbiao , Lai Yating , Wang Chao , Yu Yu , Chen Zhaobing
Published: August 2023

In recent years, tight sandstone oil and gas have been an important area for unconventional oil and gas exploration and development in China. It is of great significance to clarify the pore-throat structure characteristics of tight sandstone reservoirs to guide production practices. This study takes the tight sandstone of the sixth member of the Yanchang Formation in the Huaqing area, Ordos Basin, as an example, based on experimental methods such as high-pressure mercury intrusion, cast thin sections and scanning electron microscopy. At the same time, the pore-throat structure of tight sandstone reservoirs is divided into three types using the tube-bundle and spherical fractal models. The corresponding pore and throat radius distribution, pore-throat combination mode and influencing factors of various pore-throats are studied. The results show that the fractal dimension of type I pore-throats is the smallest, and the distribution of their pore-throat radii is the most uniform. They are dominated by intercrystalline pores and dissolution pores with tube-bundle throats and small pores with small throats. Type II pore-throats have the largest fractal dimension and the worst pore-throat uniformity. They are dominated by residual primary intergranular pores with necked throats and large pores with small throats. The type III pore-throat fractal dimension is in the middle, mainly composed of residual dissolved intergranular pores with pore-reduced throats, sheet-like and curved sheet-like throats, and large pores with large throats. The influence of different pore-throat combinations on the reservoir is reflected in the different characteristics of mercury injection parameters. The main influencing factors for the differences in the fractal dimensions of different pore-throats are diagenesis, rock composition and pore-throat combination type. Diagenesis and rock composition, in turn, affect the type and development degree of pore-throats, as well as the combination of pore-throats. The purpose of this study was to clarify the internal connection modes of different homogeneous pore-throats and their influencing factors, enrich the theoretical basis for the study of tight sandstone reservoirs and provide theoretical guidance for their exploration and development.
Experimental Modeling of Natural Processes of Nepheline Alteration
Authors: Mikhailova Julia A. , Kalashnikova Galina O. , Pakhomovsky Yakov A. , Selivanova Ekaterina A. , Kompanchenko Alena A.
Published: August 2023

Nepheline, ideally Na3K(Al4Si4O16) is a key mineral of silica-undersaturated igneous rocks. Under subsolidus conditions, nepheline is intensively replaced by numerous secondary minerals, of which various zeolites (mainly natrolite, analcime, gonnardite), as well as cancrinite, muscovite and Al-O-H phases (gibbsite, böhmite, nordstrandite) are the most common. In the rocks of the Lovozero alkaline massif (Kola Peninsula, NW Russia), nepheline is extensively replaced by the association natrolite + nordstrandite ± böhmite ± paranatrolite. To reproduce the conditions for the formation of such a mineral association, a series of experiments were carried out on the dissolution of nepheline in deionized water, 0.5 mol/L NaCl, 0.5 mol/L NaOH, and 0.1 mol/L HCl at 230 °C for 1/5/15 days. When nepheline is partially dissolved, phases and mixtures of phases precipitate on the surface of its grains, and these phases were diagnosed using X-ray powder diffraction and Raman spectroscopy. Observations in natural samples and experimental studies have shown that the nepheline alteration in the rocks of the Lovozero massif with the formation of natrolite and Al-O-H phases occurred under the influence of a high to medium salinity solution at a pH of near 6.
Highly Efficient Fluorescent Detection of Vitamin B12 Based on the Inner Filter Effect of Dithiol-Functionalized Silver Nanoparticles
Authors: Chau Phan Ba Khanh , Vu Trung Hieu , Kim Moon Il
Published: August 2023

We report a fluorescent assay for the determination of vitamin B12 (VB12) based on the inner filter effect (IFE) of 1,3-propanedithiol-functionalized silver nanoparticles (PDT-AgNPs). PDT was simply functionalized on the surface of AgNPs through Ag–thiol interaction, which leads to significantly enhanced fluorescence, with excitation and emission at 360 and 410 nm, respectively, via their thiol-mediated aggregation. Since target VB12 has strong absorption centered at 360 nm, which is almost completely overlapping with the excitation spectra of PDT-AgNPs, the VB12 induced strong quenching of the fluorescence of PDT-AgNPs via IFE. The IFE-based mechanism for the fluorescence quenching of PDT-AgNPs in the presence of VB12 was confirmed by the analyses of Stern–Volmer plots at different temperatures and fluorescence decay curves. The fluorescence-quenching efficiency of PDT-AgNPs was linearly proportional to the concentration of VB12 in a wide range of 1 to 50 μM, with a lower detection limit of 0.5 μM, while preserving excellent selectivity toward target VB12 among possible interfering molecules. Furthermore, the PDT-AgNPs-mediated assay succeeded in quantitatively detecting VB12 in drug tablets, indicating that PDT-AgNPs can serve as an IFE-based fluorescent probe in pharmaceutical preparations by taking advantages of its ease of use, rapidity, and affordability.