bluuebunny/crossref_metadata_2025 huggingface dataset:
HİDROJEN PEROKSİT PRIMING YOLUYLA DOMATES BİTKİLERİNDE TUZ STRESİNİN AZALTILMASI: ANTİOKSİDAN ENZİM AKTİVİTELERİNİN VE GEN İFADESİNDE MEYDANA GELEN DEĞİŞİMLER
Authors: Kar Musa , Gökpınar Gökhan , Doğan Özlem
Published: July 2024

Bitkiler sessil yapılarından dolayı çevrelerinde meydana gelen abiyotik ve biyotik streslerin meydana getirdiği strese faktölerina antioksidan sistemleri sayesinde cevap verir. Tuzluluk ve alkalinite bitki için oldukça önemli abiyotik stres faktörlerinin başında gelmektedir. Bitkiler bu streslere karşı toleransını artırmak için çeşitli sinyal yollarını aktive ederek streslere cevap vermeye çalışır. Tarım arazilerinde ekimi yapılan bitkileri biyotik ajanlardan koruyabilmek için pestisidler, herbisitler gibi çok çeşitli zirai ilaç kullanılmaktadır. Buna karşın, abiyotik streslere karşı savunma mekanizmasını güçlendirilecek bilinen yaygın bir uygulama yoktur. Bu çalışmada H2O2 ön uygulamasının Domates fidelerinde tuz stresini hafifletme etkisi araştırılmıştır. Bu kapsamda 4 farklı deney grubu oluşturulmuş (kontol, H2O2, Tuz, Tuz+H2O2) ve klorofil miktarı, MDA akümüslasyonu SOD, CAT, APX enzim aktivitelerinde ve ekspresyonunda meydana gelen değişimler incelenmiştir. Çalışma sonucunda priming uygulamasından sonra yalnız tuz stresi uygulanan gruba göre klorofil miktarında artış MDA birikiminde azalma meydana gelmiştir. Ayrıca, stres alakalı enzimlerin aktivasyonu yalnızca tuz stresi uygulanan gruptan anlamlı düzeyde yüksek çıkmıştır. Ekspresyon seviyeleri kontrole göre istatiksel olarak önemli düzeyde artış göstermiş, ancak CAT ve APX ekspresyon seviyeleri yalnızca tuz stresi uygulanan gruptan düşük olduğu tespit edilmiştir. Sonuç olarak H2O2 priming uygulaması bitkinin stres toleransının artırılmasına yardımcı olduğu tespit edilmiştir. Priming yöntemi bitkiler için stres etkisini hafifletmede oldukça fonksiyonel bir araç olarak kullanılabilir ancak priming ajanının çeşidi, konsantrasyonu ve maruziyet süresi primingin etkisinin düzenlenmesi için oldukça önemli unsur olduğu tespit edilmiştir.
Association of breastfeeding related musculoskeletal pain, sleep quality and physical activity among postpartum women: a literature review
Authors: Mehra Pooja , Verma Nitesh , Kaul Geetanjali , Kumar Ankit
Published: July 2024

Women often report musculoskeletal ailments during perinatal period resulting in less sleep hours and decline in physical activity. It has been speculated that physical activity can lower the frequency of muscular pain and enhance good quality sleep among women. Hence, the review aimed to investigate the association of breastfeeding related musculoskeletal pain, sleep quality and physical activity thus refining quality of life among women. Literature search was performed using search strategy on PubMed, Scopus and Pedro databases during 2019-2023. A total 54,037 articles were found via database searching out of which only 16 studies were relevant meeting the inclusion criteria. All the studies found that breastfeeding related musculoskeletal pain, sleep quality and physical activity are associated with each other. To lower the incidence of muscular pain and improve sleep quality, physical activity can be incorporated thus preventing occurrence of future complications. Hence, it has been suggested that physical activity is key solution of emerging musculoskeletal pain and broken sleep quality. Evidence from this literature supports that prenatal education emphasizing necessity of physical activity should be routinely integrated into maternal care in an effort to reduce chances of future complications.
Comércio eletrônico e usos do território brasileiro:	tipologia e topologia de grandes empresas
Authors: Venceslau Igor
Published: July 2024

A difusão das tecnologias digitais vem alterando a maneira como as atividades econômicas são realizadas, incluindo o comércio. O comércio eletrônico pode ser entendido como uma maneira sofisticada e atualizada de realizar trocas a distância, com mediação das novas tecnologias. Este artigo tem por objetivo apresentar uma tipologia e uma topologia das grandes empresas de comércio eletrônico com atuação no Brasil, contribuindo para o entendimento dos usos do território na contemporaneidade. Foram utilizados revisão bibliográfica, coleta de dados secundários em websites e plataformas de comercialização varejista, e trabalho de campo. Os resultados apresentaram uma concentração geográfica dessas empresas, com centralização do comando remoto numa única região brasileira, a despeito da recente desconcentração logística da distribuição de mercadorias.
FOTORRESPUESTA EN SUPERCONDUCTORES DE ALTA TEMPERATURA CRÍTICA
Authors: Osorio Jaime , Giratá Doris , Prieto Pedro
Published: July 2024

El campo de la superconductividad ha ganado mucha atención en los últimos años debido al descubrimiento de los cupratos superconductores de alta temperatura crítica. Además de su alta temperatura de transición, ellos muestran una variedad de propiedades físicas que los diferencian de los superconductores convencionales, dos de estas características son la fotoconductividad persistente y la superconductividad fotoinducida. En este artículo se presentan los efectos de fotorrespuesta obtenida al iluminar películas delgadas y junturas Josephson de YBaCuO y BiSrCaCuO, cuyo efecto es un aumento en la conductividad fotoinducida, la temperatura critica y en la corriente crítica en junturas Josephson, después de iluminar. Se argumenta que este efecto es debido al fotodopaje de la región deficiente de oxígeno en el enlace débil.
NEW SPECIES OF FROGS FROM LOW ANO MODERATE ELEVATIONS FROM THE CALDAS TRANSECT OF THE EASTERN FLANK OF THE CORDILLERA CENTRAL
Authors: Lynch John D.
Published: July 2024

Four additional species of Eleutlzerodactylus are reported from eastern Caldas, Colombia, bring to 28 the numher of species known along a transect between 600 and 2650 m. Eleutherodactylus orpacobates is reported for the first time away from the Cordillera Occidental and three species are named as new.
UN NUEVO NOMBRE PARA HOLOSTYLIS RENIFORMIS DUCHARTRE (ARISTOLOCHIACEAE)
Authors: González Favio
Published: July 2024

Como consecuencia de la reciente inclusión del género Holostylis dentro de Aristolochia, y de la existencia de dos homónimos previos correspondientes a A. reniformis, se publica un nuevo nombre para Holostylis reniformis (Aristolochiaceae). A la vez, se incluyen una descrip­ción detallada de esta especie y una lista de los ejemplares de herbarios estudiados.
PROYECCION DE LAS EMISIONES DE GASES DE EFECTO INVERNADERO (GEI), COLOMBIA 1998-2010
Authors: González B. Fabio , Rodríguez M. Humberto
Published: July 2024

El escenario base de las emisiones 1998-2010 fue generado a partir de las proyecciones de demanda de energía y del comportamiento del sector no-energía para el periodo. Los gases considerados fueron los mismos que se tomaron para el inventario de GEI de referencia de 1990. Una de las conclusiones más importantes es que las emisiones del sector energía que significaron el 31% de las emisiones totales en 1990, para el año 2010 representarán el 72%, mientras que las emisiones del sector no-energía decrecerán de 69% a 28% en el mismo perio­do. El total de las emisiones crecerá en el periodo 1990-2010 un 4%, pasando de 167 Mton en 1990 a 174 Mton en el 2010.
COMUNIDADES VEGETALES Y PATRONES DE DEGRADACION Y SUCESION EN LA VEGETACION DE LOS CERROS OCCIDENTALES DE CHIA­ CUNDINAMARCA-COLOMBIA
Authors: Cortés-S. Sandra P. , der Hammen Thomas Van , Rangel-Ch. J.Orlando
Published: July 2024

Se diferenciaron dos tipos básicos de vegetación: abierta que incluye las asociaciones: Dichondro repentis-Cupheetum serpyllifoliae (pastizales), Baccharido rupicolae-Dodonaeetum viscosae (matorrales bajos), Andropogono aequatoriensis-Epidendretum elongatae (vegetación casmófita), Chaetolepido microphyllae-Espeletiopsietum corymbosae (matorrales rosetosos) y cerrada con las asociaciones Miconio ligustrinae- Weinmannietum tomentosae y Daphnopsio caracasanae-Xylosmetum spiculiferae. Según la composición florística de las comunidades (incluyendo las etapas maduras y las juveniles), la profundidad del suelo, la pendiente, las unida­des topográficas, el macroclima de la región y la influencia antrópica (degradación y sucesión natural), se definieron dos líneas de sucesión.
Anarchic Ethnicity
Authors: Aronson O.V.
Published: July 2024

The chapter “Anarchist Ethnicity” makes an attempt to consider the concept of ethnicity as part of the modern politics of values. The topic of ethnicity, which arose as a scientific response to a politically discredited racial theory, nevertheless, as the author shows, does not leave the political space. Both primordialist and constructivist concepts of ethnicity retain the priority of ethnic identity (separation of oneself from another, and in political form, attitude towards the enemy) in relation to that archaic (pre-political) community, which can also be extracted from the very idea of ​​ethnos. The author proposes to consider ethnicity not as a tool for dividing communities, but as one of the forces of bringing together the weak, different, and incapable of political solidarity and mobilization. This reveals a unique ethics of ethnicity, which the author calls “ethical mythology,” since here the action of myth and ethics are inseparable. Using the example of the polemics of Derrida and Lévi-Strauss regarding preliterate societies, it is shown that the myth in which a community manifests itself in opposition to various forms of imposed political community (be it a people, a nation or an ethnic group) is a variant of arche-writing in the form in which it described in the concept of deconstruction. In fact, ethnicity contains signs of resistance to the “common meaning” and “political will”, peculiar traces of ritual, non-government practices of heterogeneous communities. The attempt made in this chapter to present such communities as the elusive source of ethnicity and as a distinguishing unit of modern political thinking, like a phoneme in linguistics, reveals the anti-authority and anti-social layer of ethnicity, which is therefore called here “anarchic”. In the chapter “Maidan: Redefining Democracy,” through an analysis of the events that occurred in Ukraine in 2013, which resulted in a change in political power in the country, the author attempts to offer a different version of democracy. It was on the Kiev Maidan, in his opinion, that the event of depoliticization of protest took place, as a result of which many words, such as “freedom”, “justice”, “trust”, “dignity”, ceased to be moral and political tools for manipulating society, but they acquired the concreteness of practical action, not reducible to politics, morality, or economics. The article shows the Maidan effect from the side of its resistance to politics, where the dominance of affective trust exceeds possible political disagreements. It is this that Spinoza, and later Antonio Negri, describes as the “multitude” (multitudo) that underlies democracy. It is this kind of democracy that realizes “freedom”, “equality” and “justice” not as political concepts, but as affects of community, allowing for the realization of both trust and risk in a world filled with political falsehood and disinformation.
Implementation of the Protective Function of Law in an Adversarial Civil Procedure
Authors: Alieskerov Mizamir A. ,   Chairman of the Judicial Chamber on Civil Cases of the Kaluga Regional Court
Published: July 2024

The article discusses the concept of the protective function of law and the connection of this function with the social purpose of law. The implementation of this function in adversarial civil proceedings has a dual character, since intra-branch protective legal relations must provide conditions for the implementation of the protective function of civil procedural law in the substantive legal sphere. The methods and features of the implementation of the protective function of law in the conditions of adversarial civil proceedings are explored.
Transformation of Democracy in Russia: From Representative to Deliberative Forms (a Legal Interpretation)
Authors: Sennikova Darya V. ,   Associate Professor of the Department of Theory and History of State and Law, Administrative Law of the Tomsk State University
Published: July 2024

Democracy, being the basis of the constitutional system, is undergoing transformation along with other legal principles enshrined in the Basic Law. Although forms of representative democracy are currently prevalent, the author comes to the conclusion that the current technical, informational and organizational conditions contribute to the development of deliberative forms of democracy and the involvement of citizens in the process of discussing of socially significant bills.
On the Methodology of the Administrative Law Regulation in the Economic Sphere
Authors: Smorchkova Larisa N. ,   Leading Research Scientist of the Department of Administrative Law and Administrative Procedure of the Institute of State and Law
Published: July 2024

The author’s vision, formed into a specific algorithm, of the methodology of legal regulation of social relations in the economic sphere, as well as the methodological features of administrative and legal regulation, is offered for broad discussion. In addition to the traditional methodological elements — subject, method, means of legal regulation, the necessity of using interdisciplinary, system-activity, level approaches, developing a thematic system and a system of principles based on the goal set to achieve is proven.
Self-Assessment of the Intercultural Competences of Medical Doctors and Nurses in Poland in the Face of Current Refugee Challenges
Authors: Freund Bożena
Published: July 2024

Health care is one of the most important systems in both society and the economy. At the same time, it is a highly complex system that is subject to an increasing number of challenges in the contemporary world.
For example, the health care system in Poland struggles primarily with inadequate numbers of nurses and medical doctors, as well as insufficient funding. A relatively new challenge is to provide for the health needs of refugees, whose number is increasing due to the war in Ukraine beyond Poland’s eastern border.
This raises the question of the substantive preparation of nurses and medical doctors to work in a culturally diverse environment. Have they had the opportunity to train in intercultural competences? How do they assess their own intercultural competences? Do they see challenges in their interactions with foreigners?
The aim of this paper is therefore to present a self‑assessment of the intercultural competences of medical doctors and nurses in Poland, in particular in the context of current refugee challenges.
In order to achieve the assumed goal, a proprietary questionnaire form was created, and a nationwide survey was conducted among a group of professionally active medical doctors and nurses.
The results of the research, in addition to providing valuable knowledge, were used to draw up specific recommendations for improving the continuing education of medical and nursing staff in the area of intercultural competences. Based on the research results, guidelines for better management in public health organisations were also created.
This text may be of interest to researchers of management in public health care organisations, and in particular human resources management in health care institutions, as well as practitioners trying to deal with the current problems facing public health management.
Áreas verdes y arbolado urbano existente en el cantón sucre, Manabi, Ecuador
Authors: Cabrera Verdesoto César Alberto , Bermúdez Chica Jennifer Fabiola , Mero Jalca Otto Francisco , García Álava Jennifer Andrea , Cali Ligua Valeria Lissete
Published: July 2024

Las áreas verdes y arbolado son parte esencial de las dimensiones ecológica, social, ambiental y económica de la sostenibilidad urbana. El objetivo de la investigación fue evaluar el arbolado en la zona urbana del cantón Sucre, con un área verde de 36 628,27 m2, donde se realizó un censo de los parques existentes, también se elaboró un inventario de las especies forestales en las parroquias Bahía de Caráquez y Leónidas Plaza. Para esto, se consideró que los parques son espacios públicos claramente delimitados, dominados por vegetación arbórea destinados como áreas verdes públicas; en la investigación se obtuvo la información dasométrica de los árboles de los 18 lugares entre ellos parques y elementos de seguridad vial (avenidas) existentes en el cantón; se determinó también las áreas, con el total de superficie de las áreas verdes y la población urbana total; según el índice verde urbano (IVU) fue de 1,85 m2/hab, para conocer a fondo los árboles de cada parque, se utilizó el análisis cartográfico en la elaboración de mapas y la georreferenciación de espacios verdes. El índice de valor de importancia ecológica donde las especies Azadirachta Indica fue la especie más representativa con 28,49% y el Tecoma stans con 1,03% la menos representativa, Margalef (2,85) reflejó con media diversidad de especies, Simpson (0,82) representó una diversidad media y Shannon-Wiener (2,98) con diversidad media. Concluyendo, que el arbolado urbano consiste principalmente en especies introducidas, con un índice verde bajo y una diversidad media según los índices de Margalef, Simpson y Shannon-Wiener.
Geraniol Abrogates Aluminum-elicited Testicular Toxicity and Endocrine-sperm Deficits by Curtailing Oxidative Inflammation and Caspase-dependent Apoptosis in Male Rats
Authors: Almalmulhim Noura , Alfwuaires Manal , Elsawy Hany , Sedky Azza
Published: July 2024

Background: Aluminum (Al) is a ubiquitous environmental toxicant associated with adverse effect on the testis. Thus, we investigated the protective effect of GER against Al-induced testicular injury and endocrine-sperm deficits in male rats. Methods: Adult male rats were randomly divided into 4 groups: Control group, GER group (100 mg/kg body weight for 28 consecutive days, orally), Al group (200 mg/kg body weight every 3 days for 28 days, ip) and GER + Al group (100 mg/kg + 200 mg/kg). Levels of testosterone (T), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were measured in serum. Testicular parameters of oxidative stress, inflammation and apoptosis were analysed, as well as sperm parameters and testis histology. Result: The Al exposure significantly (p less than 0.05) decreased levels of T, LH, FSH, IL-4 and IL-10, whereas Al increased oxidative stress, inflammation and apoptotic markers compared to the control. Al induced marked histopathological abrasions and caused adverse effects on sperm parameters compared to the control. On the contrary, the co-administration of GER with Al ameliorated the Al-induced endocrine-sperm deficits, testicular oxidative stress, cytokine inflammation and apoptosis. GER is a potential natural monoterpene for prevention of Al-induced testicular toxicity and endocrine-sperm dysfunction in rats.
Genetic and Nutritional Secrets of Groundnut Varieties Unveiled for Enhancing Farmers Income by Groundnut Value Chain Process
Authors: Kamalasundari S. , Balasubramanian P. , Anuratha A. , Arulselvi A. , Babu R. , Subbalakshmi B.
Published: July 2024

Background: Peanut (Arachis hypogaea L.) is one of the most important oil seed crops. It is nutritionally and economically a high value oil seed crop and is in the sixth most important in the world. It is also known as a “Wonder legume”. Methods: Based on the physical parameters the peanut varieties were classified as high oil content (50-53%) varieties viz.,VRI (Gn) 5, Co(Gn)4, Co7 and low oil content (44-49%). varieties viz., VRI 9, VRI10, BSR 2. Among the varieties, the best suited variety for secondary processed products namely, salted peanuts, peanut chikki, peanut butter, peanut chutney powder, masala peanut were assessed and evaluated for the nutrient composition and sensory evaluation. Result: All the varieties exhibited good source of protein, fat, crude fiber. free fatty acid and peroxide value and confirmed to the FSSAI standards. Developed secondary processed product has excellent keeping quality. scored maximum sensory score in terms of organoleptic attributes. The higher oil content peanut varieties are recommended for oil extractionand the varieties with oil content below 50% are well suited for secondary processed products. This paper gives the detailed report of choosing the suitable groundnut variety for different secondary processing. Training cum demonstration on selecting suitable variety for different processing was imparted to the farmers in improving the value chain and to get good returns. However, a diversity of value adding options are being promoted for adoption by farmers to sustainably improve and raise farmers’ household incomes livelihoods.
The Analysis of 4C-Based Learning Implementation for Islamic Religious Education Students
Authors: Destriani  , Idi Warsah  , Asri Karolina  , Sutarto  , Gerard Krzic ‎
Published: July 2024

The purpose of this study is to identify issues surrounding the application of 4C-based learning. In addition, this study looks at how lecturers address issues that arise with their pupils. The method used in this study is qualitative descriptive. Purposive sampling procedures were used in the selection of the 20 students and 2 lecturers participated in this study. Data were gathered by open-ended surveys, interviews, and observations. Data analysis involves gathering, condensing, presenting, and deriving conclusions using interactive models. Researchers found that lecturers tried to engage 4C based learning during their class. The necessary abilities, which include the capacity for critical and creative thought as well as collaboration and communication, must be tailored to the trends of the twenty-first century. Students' abilities to argue critically with others and to articulate their thoughts rationally serve as examples of this. Besides, students are able to exhibit their capacity for productive work, recognize the diversity within the team, show adaptability and a readiness to consider other people's viewpoints, assume joint accountability for group projects, and recognize the significance of each team member's contribution to a diverse group. They consider some applications such as Canva, Mind Master, Kahoot, and QR Code for their creativity supports. As well as, writing papers assignment is able to build students’ critical thinking skills. Students who possess critical thinking abilities may identify issues, come up with solutions, and gather and arrange data. Students’' ability to create topic papers and research papers serves as evidence of this.
Effect of physical activity on free fatty acids, insulin resistance, and blood pressure in obese older women
Authors: Son Woo-Hyeon , Ha Min-Seong , Park Tae-Jin
Published: July 2024

[Purpose] Obesity is characterized by a progressive increase in body fat accompanied by insulin resistance (IR) and elevated blood pressure (BP), and presents significant health risks, particularly in aged individuals. This study aimed to evaluate the effects of physical activity (PA) on free fatty acid (FFA) levels, IR, and BP in obese older women.[Methods] Twenty-three participants were randomly assigned to either the control group (CON, n = 11) or the physical activity group (PA, n = 12). The PA group was provided with a target of achieving >7,000 steps/day for 5 days each week. Body composition, FFA levels, IR, and BP were measured at pre- and post- of the 12-week intervention.[Results] The analysis revealed a statistically significant interaction between FFA (p < 0.01), IR (p < 0.01), and SBP (p < 0.001). FFA (p < 0.5), IR (p < 0.5), and systolic blood pressure (SBP) (p < 0.01) were significantly decreased in the PA group compared to those in the CON group, which showed no significant changes in FFA, IR, and SBP.[Conclusion] PA significantly decreased FFA, IR, and SBP in older women with obesity. Therefore, PA is an effective intervention for the prevention and management of obesity and cardiovascular diseases in obese older women.
The impact of exercise on depression: how moving makes your brain and body feel better
Authors: Hossain Md Najmul , Lee Jaeeun , Choi Hongseok , Kwak Yi-Sub , Kim Jongnam
Published: July 2024

[Purpose] This study aimed to comprehensively explore and elucidate the intricate relationship between exercise and depression, and focused on the physiological mechanisms by which exercise influences the brain and body to alleviate depression symptoms. By accumulating the current research findings and neurobiological insights, this study aimed to provide a deeper understanding of the therapeutic potential of exercise in the management and treatment of depression.[Methods] We conducted a systematic review of the scientific literature by selecting relevant studies published up to October 2023. The search included randomized controlled trials, observational studies, and review articles. Keywords such as “exercise,” “depression,” “neurobiology,” “endocrinology,” and “physiological mechanisms” were used to identify pertinent sources.[Results] Inflammation has been linked to depression and exercise has been shown to modulate the immune system. Regular exercise can (1) reduce the levels of pro-inflammatory cytokines, potentially alleviating depressive symptoms associated with inflammation; (2) help in regulating circadian rhythms that are often disrupted in individuals with depression; and (3) improve sleep patterns, thus regulating mood and energy levels.[Conclusion] The mechanisms by which exercise reduces depression levels are multifaceted and include both physiological and psychological factors. Exercise can increase the production of endorphins, which are neurotransmitters associated with a positive mood and feelings of well-being. Exercise improves sleep, reduces stress and anxiety, and enhances self-esteem and social support. The implications of exercise as a treatment for depression are significant because depression is a common and debilitating mental health condition. Exercise is a low-cost, accessible, and effective treatment option that can be implemented in various settings such as primary care, mental health clinics, and community-based programs. Exercise can also be used as an adjunctive treatment along with medication and psychotherapy, which can enhance treatment outcomes.
Possible effect of exercise with anti-fatigue nutrition on ROS-induced depression and suicide risk: a review
Authors: Baek Seung Hak , Baek Suji , Kim Gyoungmin , Chi Andrew Sik , Kim Erin , Hwang Dong Hyeok , Ko Sarah , Jang Hyun Joo , Lee Kang Pa
Published: July 2024

[Purpose] Epidemiological evidence shows that physical activity, including continuous stimulus changes and appropriate exercise programs, improves brain degeneration in the hippocampus, prefrontal cortex (PFC), and anterior cingulate cortex (ACC). Therefore, we investigated the possible synergistic effects of physical activity and nutrition in controlling chronic fatigue and reducing oxidative stress in patients at risk for depression and suicide.[Methods] We systematically reviewed the literature on various systemic factors related to the effects of 1) suppressing oxidative stress and 2) improving depression through exercise and nutrition. To conduct this review, we searched the PubMed database for papers published until May 1, 2024, using the terms “physical activity OR exercise” and “fatigue” OR “anti-fatigue,” “oxidative stress” and “depression” and “suicide.” We then reviewed the resulting list of articles related to antioxidant mechanisms.[Results] Appropriate physical activity and natural product intake can substantially change whole-body homeostasis and provide a way to overcome the threat of depression and suicide by regulating metabolites, scavenging free radicals, and neurotransmitters.[Conclusion] Suicide and depression prevention play crucial roles in improving patients’ quality of life. Our review provides evidence supporting the idea that exercise and antioxidant nutrition diminish oxidative stress and fatigue by improving the degeneration of the hippocampus, PFC, and ACC.
BIOATIVIDADE DO ÓLEO ESSENCIAL DE Cymbopogon citratus (DC.) STAPF SOBRE Dalbulus maidis (DELONG & WOLCOTT) (HEMIPTERA: CICADELLIDAE)
Authors: Dobler Miriam Izabel , Silvestre Wendel , Pauletti Gabriel , Bonatto Vicenço Camila
Published: July 2024

Este trabalho teve como objetivo avaliar o potencial inseticida do óleo essencial de Cymbopogon citratus nas concentrações de 0,1; 0,5; 1,0; 1,5; e 2,0% v/v como alternativa aos produtos convencionais em indivíduos adultos de D. maidis, bem como a utilização de duas testemunhas: uma positiva, composta pelo inseticida químico Perito 070 SG (acefato) 1 kg∙ha-1, e dois controles negativos, Tween 80® 0,5% v/v e água destilada. Os bioensaios foram realizados em triplicata, com três repetições de dez indivíduos por replicata, totalizando 30 indivíduos por tratamento. As plantas de milho foram transplantadas em frascos com capacidade para 2 L e foram transferidos 10 indivíduos adultos. Os tratamentos foram pulverizados e cobertos com tecido voile. Foi observado que para as concentrações de 0,1%; 0,5% e 1,0% não houve diferença significativa em relação ao controle negativo, enquanto nas concentrações de 1,5% e 2,0% v/v houve diferença significativa em relação aos controles negativos, mostrando mortalidade semelhante ao controle positivo, sendo um potencial pesticida no controle de D. maidis e potencial candidato como bioherbicida no controle de plantas voluntárias de milho por ter causado toxicidade a partir de concentrações de 1,0% v/v.
Optimization of classifier ensemble diversity
Authors: Peterson Leif E.
Published: July 2024

Ensemble diversity was investigated for 12 classifiers and 16 datasets using a generalization error and ambiguity decomposition of the model bias-variance relationship. Diversity was optimized using a genetic algorithm and particle swarm optimization. Classifiers with the greatest contribution to ensemble diversity were learning vector quantization, naïve Bayes classifier, and supervised neural gas, whereas the supervised artificial neural network (SANN) and support vector machines (SVM) classifiers were among the least informative for diversity. An important observation was that classifiers with the greatest optimized employment weights in diverse ensembles also had the greatest association between individual unoptimized diversity, D, and number of classes among datasets, with little association with dataset number of objects or features. The SANN and SVM classifiers had a significant association with the number of objects in datasets and were employed infrequently in diverse ensembles. In conclusion, the diversity of a classifier is more dependent on the number of classes of datasets and less dependent on the number of objects or features. A greater ensemble employment weight for a classifier also occurs when its range of generalization error and ambiguity over all datasets overlap.
Computational study of adsorption and photophysical properties of metallophthalocyanine dyes for DSSCs
Authors: Ramadan Ahmed M. , Fouad Mohamed A. , Hasanein Ahmed A.
Published: July 2024

Adsorption characteristics, as well as photophysical and photovoltaic properties, of symmetrically substituted phthalocyanine (Pc) with S-bridged 4-mercaptobenzoic acid (4-mercapto-Ba)-MPc, where M is a chelated metal ion situated in the center of the inner cavity of the Pc macrocycle, have been investigated. The metal has been taken to be Fe(II), Co(II), Ni(II), Cu(II), or Zn(II). We employed molecular dynamics simulation to determine the characteristics of the adsorption of these metallophthalocyanine-based dyes on the (101) surface of TiO2 anatase through the use of the Adsorption Locator code implemented in Accelrys Material studio software. The calculated adsorption energy values are negative, which indicates that adsorption can occur spontaneously. Moreover, DFT calculations of the optimum geometries, as well as TD-DFT calculations of the vertical excitation energies, at the theory levels CAM-B3LYP/LANL2DZ and M06L/LANL2DZ have been performed for these studied dyes. The free energy change of injection ΔGinject, the light harvesting efficiency (LHE), and the open-circuit potential (eVoc) for these dyes have been calculated. The nature of the intramolecular charge transfer electronic transition has been studied, and the amount of charge-transferred qCT has been calculated in all the investigated dyes.
Effects of prenatal chemical exposures on age at menarche: a scoping review of prospective studies
Authors: Sandquist Melanie , Mahabir Somdat
Published: July 2024

Background: Age at menarche is an important risk factor for health and disease, including cancer. While emerging evidence indicates that prenatal exposures to certain chemicals in the environment result in increased risk of early age at menarche (EAM), much remains unknown. Because prenatal chemical exposures are an important public health concern, potentially modifiable, and offer opportunities for disease prevention, we conducted a scoping review to assess the associations and EAM. Objectives: This scoping review aims to explore human evidence from prospective epidemiology studies on the association between prenatal chemical exposures and menarcheal timing. Methods: Searches conducted in PubMed, SCOPUS, and Embase returned 149 papers. Based on established exclusion/inclusion criteria, we included 22 prospective studies in our analysis. We assessed several chemical categories, such as agricultural chemicals, metals, phthalates, phenols, biphenyls, per-polyfluoroalkyl substances (PFAS), medications, and tobacco smoke in relation to EAM. Relevant information was then extracted from each study, tabulated, and synthesized. Results: Our scoping review found that prenatal exposures to atrazine, phytoestrogens, triclosan, 2,4-dichlorophenol, contraceptives, PFAS, polychlorinated biphenyl chemicals, and tobacco smoke were associated with early menarche. These results are based on ancillary studies of parent prospective cohorts. Discussion: We found emerging evidence that certain chemicals to which girls were exposed prenatally may have predisposed them to increased risk for EAM. There is a need for well-defined studies to investigate the links between exposures to chemicals and EAM.
Advancing Physiatric Care: A Comprehensive Case Study on Laser Therapy and Hydrotherapy Integration Post-Femoral Head and Neck Resection
Authors: Caramico Miriam , Dominicis Stefania De
Published: July 2024

Hip dysplasia is a prevalent hereditary condition affecting dogs and cats, characterized by inadequate development of the hip joint. This condition leads to pain due to capsular distension, microfractures, and joint incongruity in young animals, ultimately progressing to osteoarthritis in adult and elderly animals. The pursuit of pain relief and improved quality of life for individuals with osteoarthritis has been a focal point in several studies. In this context, veterinary physiotherapy has gained prominence in small animal practice, serving as both palliative care and a supportive modality in the clinical or post-surgical management of degenerative joint diseases. Laser therapy and hydrotherapy, recognized for their analgesic effects and capacity to promote muscle mass gain, have garnered attention for their potential efficacy in treating joint diseases. This study aims to evaluate the therapeutic effects of super pulsed laser therapy and controlled low-impact exercises (water treadmill) on a patient recovering from surgery involving bilateral femoral head and forehead resection. We observed positive outcomes, including pain resolution, improved muscle mass, and enhanced range of motion, contributing to the patient's overall recovery.
MixDeR: A SNP Mixture Deconvolution Workflow for Forensic Genetic Genealogy
Authors: Mitchell Rebecca , Peck Michelle , Gorden Erin , Just Rebecca
Published: July 2024

The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there is an intense focus on the generation of SNP profiles from evidentiary specimens for so-called forensic or investigative genetic genealogy (FGG or IGG) applications. However, FGG methods are constrained by the algorithms for genealogical database searches, which were designed for use with single-source profiles, and the fact that many forensic samples are mixtures. To enable the use of two-person mixtures for FGG, we developed a workflow, MixDeR, for the deconvolution of mixed SNP profiles. MixDeR, a flexible and easy to use R package and Shiny app, processes ForenSeq Kintelligence® (QIAGEN, Inc.) SNP genotyping results and directs deconvolution of the profiles in EuroForMix (EFM). MixDeR then filters the EFM outputs to produce inferred single-source genotypes in reports formatted for use with GEDmatch® PRO. An optional MixDeR output includes metrics that assist with testing and validation of the workflow. As the Shiny app provides a graphical user interface and the software is designed to be run offline, MixDeR should be suitable for use by any laboratory developing FGG capabilities, no matter their bioinformatic resources or expertise.
Developing a Secure Service Ecosystem to Implement the Intelligent Edge Environment for Smart Cities
Authors: Karthick Gayathri , Ezra Glenford Mapp
Published: July 2024

In the future, smart cities will provide key services including seamless communication,
intelligent transport systems, advanced healthcare platforms, urban and infrastructure management,
and digital services for local and regional government. Therefore, a new service and networking
paradigm, called the Intelligent Edge Environment, has been specified. and is known as the Intelligent
Edge Environment. As a key part of this system, a new secure service ecosystem must be developed
to provide the secure realtime movement of services on different High-Performance Edge Cloud
Systems. This paper explores these issues by introducing the following mechanisms: the Resource
Allocation Algorithm, the Resource Allocation Secure Protocol and finally the Secure Service Protocols.
These systems were integrated into the Basic Capabilities System Library and a multithreaded FUSE
client connected to the Service Management Framework. Docker was used as a migration mechanism.
A prototype was developed and implemented using a FUSE-Network Memory System in which the
Network Memory Server was migrated as users move around. The result shows that this approach
was safe and could be used to develop new applications and services for smart cities.
LSTM SMOTE: An Effective Strategies for DDoS Detection in Imbalanced Network Environments
Authors: Efendi Rissal , Wahyono Teguh , Widiasari Indrastanti Ratna
Published: July 2024

In detecting DDoS, deep learning faces challenges and difficulties such as high computational demands, long training times, and complex model interpretation. This research focuses on overcoming these challenges by proposing an effective strategy for detecting DDoS attacks in unbalanced network environments. This research uses SMOTE to increase the class distribution of the data set by allowing models using LSTM to learn time anomalies effectively when DDoS attacks occur. The experiments carried out have shown significant improvement in the performance of the LSTM model when integrated with SMOTE. These include validation loss results of 0.048 for LSTM SMOTE and 0.1943 for LSTM without SMOTE, accuracy of 99.50 and 97.50. Apart from that, there was an increase in the f1 score from 93.4% to 98.3%. In this research, it is proven that SMOTE can be used as an effective strategy to improve model performance in detecting DDoS attacks on heterogeneous networks, as well as increasing model robustness and reliability.
Population-Based Incidence and Mortality Rates of Hematologic Malignancies regarding the Adult Population of Crete, Greece, and Analyses of Their Time Trends and Their Geographical Dis-Tribution: A First Approach from the Cancer Registry of Crete (CRC) for a 22-Year Time Period (1992–2013)
Authors: Lionakis Stelios , Sifaki-Pistolla Dimitra , Papadaki Helen A. , Mavroudis Dimitrios , Lionis Christos
Published: July 2024

Population-based data on hematologic malignancies (HM) are rare in Greece regarding adults (≥18 years old). The aim of this study was the assessment of the burden of these malignant neoplasms (MN) for adults in Crete. The study assessed temporal trends of incidence and mortality, depicted their spatial distribution and extracted net-survival curves of patients. Population-data on these MN were obtained from the database of the Cancer Registry of Crete, for a 22 year time period (1/1/1992-31/12/2013). All HM were classified into four main groups of diseases: (1) Hodgkin’s lymphoma (HL); (2) Non-Hodgkin’s lymphomas (NHLs); (3) Multiple myeloma (MM); and (4) All chronic and acute leukemias. Annual, gender-specific, age standardized incidence and mortality rates were estimated (ASIR/100.000/year; ASMR/100.000/year). A total of 3,380 newly diagnosed cases were included in the final analyses; All ASIRs/100,000 increased significantly throughout the study period presenting differences in their geographical distribution of rates among municipalities of Crete. ASIRs for NHLs, HL, MM, leukemias and for all 4 MN were 13.1, 2.6, 4.7, 11.7 and 32.1, respectively, in 2013. Five-year net-survival for patients diagnosed with NHLs, HL, MM and leukemias were: 82%, 85%, 52% and 56%, respectively. This first research article studying a long period of time for adults in Greece generates hypotheses on the existence of risk factors that may partly explain this variation of rates.
Synthesis, Characterization and Cytotoxic Behavior against Hela of Iridium (III) Complexes, Half Sandwich Type
Authors: García Sánchez Gabriel , Canales Martínez Alfonso , Pérez Pastor Rosa María , Florenciano López Gloria , Romero Castellón Isabel , Víllora Gloria
Published: July 2024

In this paper, we describe the synthesis and characterization of iridium (III) half sandwich complexes of stoichiometry [Cp+IrCl2L] with Cp = 5-C5 EtMe4; L = alanine anhydride (I), ortho- (II) and para-aminophenol (III). For comparative purposes, the ionic complex [Cp*IrCl(o-phen)](PF6); Cp* = (5-C5Me5) (IV) has been also synthesized and characterized. All the isolated complexes have been characterised by C, H and N elemental analysis; infrared and 1H nuclear magnetic resonance spectroscopies; 1H-1H COSY; mass spectrometry (ESI/TOF), thermogravimetry and, in the case of (IV), by conductivity measurements. The cytotoxic behaviour of the isolated complexes was studied against HeLa and complexes (III) and (IV) were found to have an IC50 close to 160-170 m, quite close to the IC50 value of cisplatin which was found to be 134,7 m, indicating that they are good cytotoxic agents. However, complexes (I) and (II) showed IC50 values above 250 m indicating their low cytotoxicity.
Approximate and Sample Entropy of the Center of Pressure during Unperturbed Tandem Standing: Effect of Altering the Tolerance Window
Authors: Wesley Jayla , Rhodes Samhita , Zeitler David W. , Alderink Gordon
Published: July 2024

Approximate entropy (ApEn) and sample entropy (SampEn) are statistical indices designed to quantify the regularity or predictability of time series data. Although ApEn has been a prominent choice for use in the analysis of non-linear data, it is currently unclear as to which method and parameter selection combination is optimal for its application in biomechanics. The goal of this research was to examine the differences between ApEn and SampEn related to center of pressure (COP) data during tandem standing balance tasks, while also changing the tolerance window, r. Six participants completed five, 30-second trials, feet-together and tandem standing with eyes-open and eyes-closed. COP data (fs = 60 Hz, downsampled from 1200 Hz) from ground reaction force platforms were collected. ApEn and SampEn were calculated using a constant vector length, i.e., m = 2, but differing values of r (tolerance window). For each of the participants, four separate one-way analysis of variance analyses (ANOVA) were conducted for ApEn and SampEn in the anterior-posterior (AP) and medial-lateral (ML) directions. Dunnett's intervals were applied to the one-way ANOVA analyses to determine which tandem conditions differed significantly from the baseline condition. ApEn and SampEn provided comparable results in the predictability of patterns for different stability conditions, with increasing instability, i.e., tandem eyes closed postures, being associated with greater unpredictability. The selection of r had a relatively consistent effect on mean ApEn and SampEn values across r = 0.15 * SD to r = 0.25 * SD, where both entropy methods tended to decrease as r increased. Mean SampEn values were generally lower than ApEn values. The results suggest that both ApEn and SampEn indices demonstrated relative consistency and were equally effective in quantifying the level of the center of pressure signal regularity during quiet tandem standing postural balance tests.
Biodiversity Assessment of a Mississippi River Backwater Complex Using eDNA Metabarcoding
Authors: Ludwig Eric J. , Lee Veronica M. , Berkman Leah K. , Geheber Aaron D. , Duvernell David D.
Published: July 2024

The backwater lowland habitats of large rivers, like the Mississippi River in North America, present complex often inaccessible environments for traditional capture-based fish biodiversity sampling. Our knowledge of the assemblages of fishes that occupy such habitats are often incomplete, and this can compromise management efforts. We employed environmental DNA (eDNA) metabarcoding methods to sample a Mississippi River bottom wetland system to assess ichthyofaunal diversity, and assemblage structure across habitat types, and we compared our results to capture-based survey records for the same habitats. We collected water samples in spring and fall of 2022 from slough, ditch, shallow lake and bayou habitats that varied in depth, vegetation, seasonal variability, and connectivity to the Mississippi River channel. We detected a diverse array of fish species that included 51 taxa. Nearly all species previously documented in the habitats were detected by eDNA metabarcoding, and we increased the number of documented species by more than a third. Most of the species were ubiquitous across the range of habitats, but there was also substantial assemblage structure, with some species exhibiting clear habitat specificity. Fall sampling was limited to the deeper bayou habitats where seasonal variation between spring and fall was minimal. eDNA metabarcode sampling was demonstrated to be effective at detecting invasive species as well as uncommon species, which included several species of conservation concern.
E-GTN: Advanced Terrain Sensing Framework for Enhancing Intelligent Decision Making of Excavators
Authors: Zhao Qianyou , Gao Le , Wu Duidi , Meng Xinyao , Qi Jin , Jie Hu
Published: July 2024

The shift towards autonomous excavators in construction and mining is a significant leap towards enhancing operational efficiency and ensuring worker safety. However, it presents challenges such as the need for sophisticated decision-making and environmental perception due to complex terrains and diverse conditions. Our study introduces the E-GTN framework, a novel approach tailored for autonomous excavation that leverages advanced multisensor fusion and a custom-designed convolutional neural network to address these challenges. Results demonstrate that GridNet effectively processes grid data, enabling the reinforcement learning algorithm to make informed decisions, thereby ensuring efficient and intelligent autonomous excavator performance. The study concludes that the E-GTN framework offers a robust solution for the challenges in unmanned excavator operations, providing a valuable platform for future advancements in the field.