bluuebunny/crossref_metadata_2025 huggingface dataset:
Membangun Model Tata Kelola Strategis dalam Strategi Peningkatan Informasi Keimigrasian Melalui Expo dan Konferensi di Indonesia, Endekatan Metodologi Soft System
Authors: Sarsito Aditya , Fitriati Rachma
Published: December 2023

Di Indonesia, expo dan konferensi mengenai ketenagakerjaan, pariwisata, atau bisnis masih diorganisir secara terpisah dan, maka dari itu, perlu diintegrasikan dengan lebih baik. Kegiatan-kegiatan expo dan konferensi ini kontras dengan sifat multidimensional dari proses keimigrasian. Organisasi layanan keimigrasian selalu berada dalam dinamika tinggi karena fungsi dari keimigrasian secara langsung terkait dengan mobilitas orang yang selalu mengejar perubahan. Penelitian ini bertujuan untuk menganalisis model tata kelola strategis dalam meningkatkan informasi keimigrasian melalui expo dan konferensi. Studi ini menggunakan metodologi soft system atau SSM dalam pemodelan aktivitas terkait imigrasi. SSM cocok digunakan dalam penelitian ini karena dapat melihat situasi sosial yang kompleks dan melibatkan berbagai sudut pandang. Hasil studi menunjukkan bahwa diperlukan pendirian sebuah acara besar internasional, yaitu Indonesia Immigration Expo and Conference, sebagai forum tata kelola strategis terintegrasi dan tata kelola kolaboratif untuk menyediakan informasi yang benar tentang keimigrasian di Indonesia. Selain itu, dengan diberlakukannya Peraturan Pemerintah No. 40 tahun 2023 tentang imigrasi dalam bentuk kebijakan “Golden Visa,” perubahan dalam periode pemberian visa dan izin tinggal diharapkan dapat menarik lebih banyak investasi asing. Acara internasional besar ini diharapkan berfungsi sebagai jaringan sosial karena mengumpulkan kedutaan, pengusaha, universitas, dan agen pariwisata dalam satu tempat. Studi ini merekomendasikan keterlibatan pemangku kepentingan dalam mendorong desain tata kelola strategis dan tata kelola kolaboratif untuk setiap pemangku kepentingan.
In Silico Prediction of Toxicological and Pharmacokinetic Characteristics of Medicinal Compounds
Authors: Vassiliev P. M. , Golubeva A. V. , Koroleva A. R. , Perfilev M. A. , Kochetkov A. N.
Published: December 2023

Scientific relevance. Studies of the toxicological and pharmacokinetic properties of medicinal compounds are a crucial stage of preclinical research; unsatisfactory results may invalidate further drug development. Therefore, the development of in silico methods for a preliminary pre-experimental assessment of toxicological and pharmacokinetic properties is a relevant and crucial task.

Aim. The study aimed to review current approaches to in silico prediction of the absorption, distribution, metabolism, excretion, and toxicity (ADMET) parameters of pharmacologically active compounds, in particular, the most important toxicological and pharmacokinetic parameters, and to present the results of the authors’ own research in this area.

Discussion. According to the review of models for predicting the toxicological properties of chemical compounds (acute toxicity, carcinogenicity, mutagenicity, genotoxicity, endocrine toxicity, cytotoxicity, cardiotoxicity, hepatotoxicity, and immunotoxicity), the accuracy of predictions ranged from 74.0% to 98.0%. According to the review of models for predicting the pharmacokinetic properties of chemical compounds (gastrointestinal absorption; oral bioavailability; volume of distribution; total, renal, and hepatic clearance; and half-life), the coefficient of determination for the predictions ranged from 0.265 to 0.920. The literature review showed that the most widely used methods for in silico assessment of the ADMET parameters of pharmacologically active compounds included the random forest method and the support vector machines method. The authors compared the literature data with the results they obtained by modelling 12 toxicological and pharmacokinetic properties of chemical compounds using the consensus method in the IT Microcosm system and artificial neural networks. IT Microcosm outperformed the models described in the literature in terms of predicting 2 toxicological properties, including carcinogenicity and blood–brain barrier penetration (the prediction accuracy reached 93.4%). Neural network models were superior in predicting 4 toxicological properties, including acute toxicity, carcinogenicity, genotoxicity, and blood–brain barrier penetration (the prediction accuracy reached 93.8%). In addition, neural network models were better in predicting 3 pharmacokinetic properties, including gastrointestinal absorption, volume of distribution, and hepatic clearance (the coefficient of determination reached 0.825).

Conclusions. The data obtained suggest that artificial neural networks are the most promising and practically significant direction for the development of in silico systems for predicting the ADMET characteristics of new medicinal products.
Digital Pharmacotherapy Support for Medication Adherence
Authors: Zaveryachev S. A. , Lotnik E. E. , Gilavyan M. A. , Yusupovskaya E. A. , Koshechkin K. A.
Published: December 2023

Scientific relevance. Medication adherence is an important condition for effective and safe treatment. The adherence of patients to prescriptions is tracked by assessing their condition, counting the pills taken, and using other indirect methods. Digital technologies can help healthcare providers improve their patients’ medication adherence.

Aim. The authors aimed to review literature describing the medication adherence impact on treatment effectiveness, as well as digital solutions accompanying pharmacotherapy.

Discussion. Poor adherence to treatment is a significant risk factor for patients. The most common examples of poor adherence are omissions and delays in the timing of doses. Compared with classical daily dosing, individualised regimens significantly increase the risk of adherence errors. Significant consequences of non-adherence include exacerbation of the disease, insufficient effectiveness of treatment, adverse drug reactions, and drug resistance. Promising hardware and software approaches to supporting medication adherence include innovative technological solutions (pillboxes, bottles with electronic reminder systems, digital pills, and smart medication adherence monitoring systems), mobile apps, and chatbots.

Conclusions. Digital solutions to support pharmacotherapy help improve patients’ adherence to their dosing regimens and individualise their treatment. Further research is needed to select the most promising areas and develop novel digital technologies.
On the detection of ionospheric disturbances caused by powerful underground explosions by GNSS radiosounding
Authors:   Lomonosov Moscow State University, 119991, Russia, Moscow, Leninskie Gory, 1, bld. 2, Padokhin A.M. , Shalimov S.L. ,   Schmidt Institute of Physics of the Earth, 123242, Russia, Moscow, B. Gruzinskaya str., 10, bld. 1
Published: December 2023

Using dense networks of GNSS receivers, an analysis of the ionospheric responses to two underground explosions with a magnitude less than the existing threshold for detecting the ionospheric response to earthquakes was carried out. It is shown that when regestering these responses, it is necessary to take into account the possible anisotropy of the propagation of atmospheric disturbances at ionospheric altitudes due to both large-scale wind structures and the inclination of the geomagnetic field. Taking these factors into account makes it possible to reduce the magnitude threshold (compared to that established for earthquakes) of impulse lithospheric sources (explosions, volcanic explosions), the response to which can still be detected in the ionospheric total electron content variations.
Влияние условий выращивания озимой пшеницы на фитосанитарное состояние посевов и продуктивность
Authors: Воронов Сергей Иванович , Киричкова И. В. , Соломатин А. В.
Published: December 2023

Защита растений в технологиях возделывания новых и перспективных сортов зерновых культур является важной составляющей частью в сохранении выращиваемого урожая, поскольку потери от вредителей, болезней и сорняков достигают 30 %. В период с 2019 по 2021 г. на опытном поле в Московской области на дерново-подзолистых почвах проводили двухфакторный опыт по возделыванию озимой пшеницы сортов Московская 40, Московская 56, Московская 27 и Немчиновская 24. Урожайность сортов озимой пшеницы повышалась с увеличением уровня интенсификации их возделывания. Установлена существенная разница получаемого урожая между уровнями применения минеральных удобрений и средств защиты растений. Наибольшая урожайность озимой пшеницы формировалась на сортах Московская 40 (9,77 т/га) и Московская 27 (9,74 т/га) при выращивании их с применением высокоинтенсивной технологии, включающей основное внесение минеральных удобрений N30P120K180; подкормки N60 + N30 + N30 (растительная и почвенная диагностика), а также систему защиты растений в виде применения высокоэффективных фунгицидов, инсектицидов и гербицидов.
Лабораторный сортовой контроль в практике первичной селекции и семеноводства, идентификации и сортовой чистоты семян зерновых культур
Authors: Клименков Фёдор Иванович , Клименкова Ирина Николаевна , Иванова Любовь Петровна , Градсков Сергей Матвеевич , Упелниек Владимир Петрович
Published: December 2023

Использование метода вертикального электрофореза запасных белков семян в лабораторной практике доказало свою высокую эффективность на всех этапах проведения селекционного процесса, ведения первичного семеноводства и сортового контроля при дальнейшем обороте сортовых партий семян зерновых культур. Проведены электрофоретические исследования и сделан доказательный вывод, в какую фазу спелости зерновки возможно проводить подобные исследования. Исследования проводили в 2021 – 2022 гг. по вегетирующим растениям зерновых культур — пшеница мягкая озимая, озимая рожь, тритикале озимая и яровая, трититригия, овес и ячмень яровые. По результатам исследований доказано, что запасные спирторастворимые проламиновые белки уже полностью сформированы в фазу молочной спелости, а именно в фазу сформированной зерновки на 2/3 от общей ее формы. Использование метода электрофореза в фазу молочной спелости зерновых культур дает неоспоримое преимущество в принятии решения по дальнейшему направлению использования посевов зерновых культур (дальнейшего воспроизводства или выбраковки из категории сортовых).
Особенности ростовых процессов сортов и линий озимой пшеницы на ранних этапах онтогенеза в условиях солевого стресса
Authors: Сандухадзе Баграт Исменович , Марченкова Людмила Александровна , Мамедов Рамин Закирович , Павлова Ольга Викторовна , Крахмалёва Мария Сергеевна , Чавдарь Раиса Федоровна , Сандухадзе Эмзари Константинович , Орлова Татьяна Григорьевна , Бугрова Валентина Васильевна , Савинов Евгений Викторович
Published: December 2023

Оценены морфофизиологические показатели начальных этапов роста и развития у 6 сортообразцов озимой пшеницы на фоне токсического воздействия хлоридом натрия и без него. Показаны результаты воздействия засоления на морфофизиологические параметры органов проростков, их высокая чувствительность к стресс-фактору, наиболее выраженная в угнетении длины и массы ростков и корешков — в среднем на 59,5; 60,5 и 44,0 % соответственно. При определении весового соотношения биомассы корней к биомассе ростков (индекс RSR) выявлены образцы с самыми высокими показателями, среди которых в варианте без засоления — линии Эритроспермум 106/22, 606/19 и 72/21; в условиях солевого стресса — сорта Московская 39, Московская 56 и линия Эритроспермум 2294/12. Изменения индекса RSR в стрессовых условиях дают основание полагать, что перераспределение пластических веществ у указанных сортов идет в сторону подземных, у линий — надземных органов растений. По результатам баллового ранжирования указанные линии отличаются самым высоким рейтингом биологической полноценности, а сорта — способностью тормозить воздействие токсичности солевого стресса. Анализ корреляционной сопряженности между изучаемыми параметрами показал, что урожайность и масса 1000 семян тесно взаимосвязаны с активизацией ростовых процессов корневой системы, особенно с массой зародышевых корешков — r = 0,84 и 0,82, с индексом RSR — r = 0,76 и 0,59, солеустойчивостью — r = 0,87 и 0,85 соответственно.
Лесообразовательный процесс в материнском древостое и на лесосеках в полезащитных лесных полосах Каменной степи
Authors: Тунякин Владимир Дмитриевич , Рыбалкина Наталия Владимировна
Published: December 2023

Изучена динамика изменения породного состава искусственно созданных полезащитных лесных полос (ПЛП) 124 – 125-летнего возраста Воронежской области с главными породами дуба и ясеня. Показано состояние древостоя на лесосеках лесовосстановительных рубок, заложенных в разном возрасте лесной полосы. В настоящее время в материнском древостое лидирующее положение в 1-м ярусе заняли дуб, ясень (обыкновенный и пушистый). После массовой гибели ясеня в 2019 г. от нашествия ясенёвой изумрудной узкотелой златки в 1-й ярус вышла часть деревьев 2-го яруса — клён остролистный и липа. Породный состав опушек в основном состоит из клёна ясенелистного, торцевые опушки — из тёрна. Ширина насаждений по проекциям крон увеличилась за счёт разрастания опушек, причём ширина северных опушек больше южных, и составляет 69 – 73 м. В материнском древостое ПЛП сформировались все основные компоненты лесной среды: многоярусность, подрост лесообразующих пород (кроме дуба), подлесок, самосев, лесная подстилка и лесные опушки. То же самое произошло и на поперечной лесосеке длиной 82 м по ширине полосы. На продольной лесосеке шириной 17 м деградация порослевого древостоя отмечена на 60-й год после лесовосстановительных рубок. Условия для развития подроста являются неблагоприятными из-за крон материнского древостоя, нависающих над лесосекой, и плотной лесной опушки. Дан прогноз дальнейшего развития материнского древостоя и древостоя на лесосеках.
Инновации в производстве бионутриентов на основе сочетания гуматов низинного торфа и силатранов
Authors: Широков Юрий Александрович , Мочунова Наталья Александровна , Понизовкин Дмитрий Андреевич , Тихненко Валерий Геннадьевич
Published: December 2023

Статья посвящена проблеме повышения экологической безопасности сельского хозяйства при минимизации применения химических препаратов за счет активирования обменных процессов гуминовыми бионутриентами на основе кавитационной обработки водной суспензии низинного торфа. Предложен вариант технологии и технологической линии, позволяющей на основе применения кавитации повысить эффективность гуминовых веществ торфа. Кавитация позволяет при физическом воздействии на длинные молекулы гуминовых веществ в водной суспензии торфа одновременно с ультразвуковыми колебаниями и пульсирующим сверхвысоким давлением в гидродинамическом кавитаторе обеспечить дробление конгломератов молекул гуминовых веществ на низкомолекулярные осколки, что повышает их активность. Разработана технологическая схема цеха. Полученный продукт прошел проверку эффективности на озимой пшенице. Показано заметное увеличение урожайности при сохранении высоких продовольственных качеств.
Organisational
culture and balanced scorecard
Authors: Oliveira Cidália , Rodrigues Margarida , Silva Rui , Franco Mário
Published: December 2023

This study aims to identify and characterize the culture of the largest exporters without the Balanced Scorecard (BSC) and with the BSC implemented. In addition, it confirms whether there are different characteristics in the type of organizational culture of the largest exporters without the BSC and with the BSC. To achieve this objective, data were collected through questionnaires sent to the 250 largest exporters in Portugal. Multivariate statistical techniques were used to validate the research hypotheses. This research shows that the Adhocracy (turbulent management) culture type prevails in organizations without BSC, while the Market (productivity) culture type prevails in organizations with BSC. The study is based on the characterization of the culture type of the organizations. This characterization is significant because organizational culture shapes and differentiates organizations’ actions, goal definitions, and strategic objectives, which can affect organizational performance. Although recent literature has addressed organizational culture and performance monitoring in isolation, not many studies have been found that link the topics of organizational culture, BSC, and performance.
Basic Psychological Needs Predicting Physical Activity Participation among Young Adults
Authors: Adelusi Joseph O. , Oguntuase Solomon B. , Jaiyeoba Oluwatoyin M.
Published: December 2023

It is alarming that despite the numerous accrued benefits of physical activity participation, many young adults in tertiary institutions engage in inactive and sedentary lifestyles, which can be linked to many cases of morbidity and mortality. However, according to the self-determination theory (SDT), individuals have three basic psychological needs (BPNs) that are essential for healthy growth, development and well-being. The necessity to fulfill these BPN’s can stimulate and encourage young adults to engage in regular physical activity and enhance their well-being. Therefore, this study examined the role of BPN’s in predicting physical activity participation among young adults in Nigerian private university. A total of 735 students, comprising 408 males (55.5%) and 327 females (44.5%), with ages ranging from 16 to 35 years (mean = 22.8; SD = 5.42), were randomly selected from a private university in the South-west, of Nigeria. The Basic Psychological Needs in Exercise Scale (BPNES) and the International Physical Activity Questionnaire–Short Form (IPAQ-SF) were used to collect data. Data analysis was conducted using descriptive statistics, correlation and multiple linear regression analysis. The results of the study showed that the BPN’s of autonomy (r =0.233, p<0.05); competence (r =0.188, p < 0.05), and relatedness (r = 0.477, p<0.05) positively correlated with physical activity participation. Additionally, the results found that 25% had low, 57.1% had moderate and 17.8% had high levels of physical activity participation among the participants. There was a significant gender difference between males and females’ in their levels of participation in physical activity (t =2.866, p < 0.05), with males reporting higher mean scores than their female counterpart. Regression analysis showed that BPN’s predicted physical activity participation among young adults (F (3,731) = 73.968, p < 0.05) with 23% of its variance accounted for by the independent variables. Furthermore, autonomy (ß = 0.071, t = 1.970, p < 0.05) and relatedness (ß = 0.478, t =12.589, p < 0.05) were predictors of physical activity participation with relatedness being reported as the most potent predictor. These findings provide an insight into focus the importance of satisfying the relatedness and autonomy aspects of BPN’s in young adults. Developing interventions that target these identified indices can promote continuous and regular participation in physical activity. Keywords: basic psychological needs, relatedness, autonomy, physical activity, young adults ‬
Estimates of matrix solutions of operator equations with random parameters under uncertainties
Authors: Nakonechnyi O. G. , Zinko P. M.
Published: December 2023

We investigate problems of estimating solutions of linear operator equations with random parameters under conditions of uncertainty. We establish that the guaranteed rms estimates of the matrices are found as solutions of special optimization problems under certain observations of the system state. As the output signals of the system, we have observations that are described by linear functions from the solutions of such equations with random right-hand sides, which have unknown second moments. Under the condition that the observation second moments of the right-hand parts and errors belong to certain sets, it is proved that the guaranteed estimates are expressed through solutions of operator equation systems. When the linear operator is given by the scalar product of rectangular matrices, a quasi-minimax estimate and its error are constructed. It is shown that the quasi-minimax estimation error tends to zero when the number of observations tends to infinity. An example of calculating the guaranteed rms estimate of the matrix's trace, which is a solution of a matrix equation with a random parameter, is given.
The effect of zinc application on growth and alleviating shoot concentration of cadmium in durum wheat plant growth under conditions of salt and cadmium stress
Authors: OZKUTLU Faruk
Published: December 2023

A study was conducted in a greenhouse to investigate the effect of the combination of cadmium (Cd) and salinity (NaCl) stress in zinc (Zn) deficiency on growth, Cd accumulation in durum wheat (Triticum turgidum L. durum, cv. Balcali-2000), and micro (Zn, Fe, Cu, Mn) minerals differing in salt tolerance. The negative effects of Cd and NaCl stress on plant growth and Cd accumulation detected to alleviate Cd uptake on wheat growth increasing zinc application. The results revealed that Cd, NaCl and their combined stresses reduced shoots dry matter and Cd concentration in shoots increased compared to control pots. In increasing Cd and NaCl treatments, increasing Zn application significantly decreased the Cd concentration in shoot. In particularly, the decrease in Cd concentration was more noticeable with the improvement of Zn nutrition of plants at low doses of NaCl and Cd. The effect of increasing zinc treatments on reducing Cd accumulation decreased to slightly at high doses of Cd and NaCl. According to the results it can be suggested that Zn application to soils with low Cd content and medium salinity can be reduce Cd uptake by durum wheat.
Struggling to Belong: Evidence From a Survey of Youth Belonging in Public Schools
Authors: Rodriguez Sophia , Wy Gabrielle Cabrera
Published: December 2023

This brief reports findings from a survey with middle and high school youth in a midsize district in the Mid-Atlantic. We find that belonging varies by race and ethnicity for young people. Overall, Black and Latino/x youth report lower belonging when compared to their White peers in a pro-diversity and inclusion district. Implications for policy and practice are addressed to improve sense of belonging for racially/ethnically and linguistically diverse youth.
“Flights for Freedom With Her Words”: Black, Latinx, and Polynesian Girls Co-Conspiring Against Misogynoir Through Love
Authors: Wong Casey Philip
Published: December 2023

I examine how youth racialized and gendered as Black girls co-conspired to challenge misogynoir with their peers racialized and gendered as Latina/x and Polynesian girls. I investigate how they did so within an after-school space at a public charter high school that came to be known as the “Critical Feminisms Club.” Thinking about the space alongside the girls in the club, I reveal how they politically and pedagogically engaged love to (a) (re)author the stories of Black girls and (b) challenge the material and ideological misogynoir that circumscribed Black girls’ lives, possibilities, and futurities within their lives and schooling. They (re)narrated how they should be in relation with and responsible to each other as collective, co-relational, and interdependent beings, recognizing how Black womanness/girlness was a genre of being human that was specifically targeted for enclosure, exploitation, and elimination. Their love-politics engaged pedagogy to remake the world such that the safety and protection of Black girls and gender-nonconforming youth was a necessity and priority, which they saw in turn as bound to the safety and protection of the non-Black identified Latina/x and Polynesian girls who accepted this interdependence and mutual responsibility.
Investigation of Metapodium and Acropodium Bones in Siirt-Colored Mohair Goat (Capra hircus) by 3D Modeling
Authors: İşbilir Fatma , Güzel Barış Can
Published: December 2023

Studies on Artiodactyla species benefit from the use of metapodial bones. Being one of the bones that completed its development early and being well preserved because it is not affected by environmental conditions, it can be unearthed as a single piece in archaeological excavations. In recent years, the disadvantages of 2D images have contributed to developing 3D modeling methods in medicine. Adult (1-3 years old), 10 male and 10 female Siirt-colored Mohair goat metacarpus and forelimb digit bones (phalanx proximalis, phalanx media and phalanx distalis) were used in our study. Bones were scanned with a computed tomography device. The resulting images were saved in DICOM format and 3D models were created using a special software. 14 osteometric measurements were taken from the metacarpus and 12 from the digit bones. The results were evaluated statistically. As a result of the statistical evaluation, in the metacarpus; Smallest Breadth of diaphysis (Sd), Breadth of distal (Bd), Medio-lateral width of condylus medialis width of condylus medialis (WCM), Depth of proximal (Dp), Antero-posterior diameter of external trochlea of condylus medialis (Dem) and Antero-posterior diameter of internal trochlea of condylus medialis (Dim) parameters were found to be statistically significant between males and females (P
Tantangan Ideologi Politik Indonesia Di Era Globalisasi
Authors: rachmadani Discha ayu
Published: December 2023

AbstrakPenelitian ini bertujuan untuk menganalisis tantangan yang dihadapi oleh ideologi politik di era globalisasi. Penelitian ini menggunakan metode deskriptif analisis yaitu dengan mengumpulkan data dari sumber literatur, jurnal, dan studi kasus yang relevan untuk mendapatkan pemahaman yang lebih mendalam tentang tantangan yang dihadapi oleh ideologi politik dalam konteks globalisasi. Dalam era globalisasi ini, ideologi Pancasila telah menghadapi berbagai tantangan yang semakin kompleks. Globalisasi telah membawa berbagai tantangan baru bagi ideologi politik indonesia, termasuk penyebaran ideologi asing, polaritas politik, dan penurunan masyarakat terhadap nilai-nilai pancasila.Globalisasi juga membawa pengaruh besar terhadap perubahan sosial, politik, ekonomi, dan budaya, yang tidak jarang berdampak pada pemahaman dan implementasi Pancasila sebagai ideologi bangsa indonesia. Karya tulis ini mencoba untuk menganalisis tantangan-tantangan tersebut dan mencari solusi yang mungkin untuk memperkuat posisi pancasila sebagai ideologi negara. Melalui penelitian dan analisis mendalam,karya tulis ini berharap dapat memberikan wawasan baru tentang bagaimana indonesia dapat mempertahankan identitasnya di tengah arus globalisasi. Tantangan tersebut meliputi penyebaran ideologi lain yang dapat menggoyahkan nilai-nilai Pancasila, perggeseran nilai-nilai luhur Pancasila oleh gaya hidup modern, dan pengaruh teknologi informasi yang berpotensi merusak kebhinekaan. Meskipun demikian, pancasila sebagai ideologi politik harus terus dipertahankan serta diterapkan di dalam kehidupan sehari-hari untuk menjaga keutuhan dan kedaulatan bangsa Indonesia di tengah arus globalisasi.
ANALISIS STUDY KELAYAKAN BISNIS PADA PENGEMBANGAN TOKO SELALU PROMO DITINJAU DARI ASPEK PEMASARAN DAN KEUANGAN
Authors: watiningsih siti daniah
Published: December 2023

This study aims to analyze the feasibility of business at Toko Selalu Promo in terms of marketing and financial aspects. This research is a qualitative field research, by taking the object of research at Toko Selalu Promo. Data collection in this study was obtained through interviews, observations, documentation with sources related to Toko Selalu Promo, namely the owner and customers.The results of the business feasibility analysis from the marketing aspect are said to be feasible, namely having a strategic location, affordable prices and attractive promotions. The analysis of business feasibility from the financial aspect results in that the capital comes from the owner.
Pemberdayaan Masyarakat Melalui Industri Batik di Pekalongan dengan Implementasi Strategi Bisnis Syariah
Authors: Astuti Hepy Kusuma
Published: December 2023

This research aims to explore the marketing strategies of Pekalongan Batik Entrepreneurs with the type of research through literature studies and qualitative field studies. Data collection techniques using interviews, observation and documentation. The results of the study can be concluded that Pekalongan Batik Entrepreneurs have carried out the marketing strategy of the marketing mix. They produce various kinds of batik. The methods used are payment in cash and on time, distribution to the market, opening batik shops. The market coverage starts from within the city, outside the city, to outside Java. They use promotion with direct sales and utilize social media technology. Batik entrepreneurs have generally implemented the principles of the sharia marketing mix. As for those who have not perfected the principles of sharia, such as using an interest-based payment system. In addition, there are still entrepreneurs who dispose of batik wastewater directly into waterways and rivers before it is treated first. The strength of batik entrepreneurs in Pekalongan is that they are able to produce batik products with various types, motifs and patterns. The weaknesses include inadequate production space, limited capital, incompetent labor, and high distribution costs for consumers outside the city. The opportunity for Pekalongan Batik entrepreneurs is to maximize existing technology. Meanwhile, the threats are raw materials that tend to increase but the selling price is getting lower and the competition of batik entrepreneurs.
PENAMPILAN PERMAINAN MUSIK ANSAMBEL PADA KEBAKTIAN MINGGU DI JEMAAT BETLEHEM OESAPA BARAT
Authors: Banunaek Kristin Verina Opa Vira
Published: December 2023

abstrakPenampilan ansambel di Jemaat Betlehem Oesapa Barat menjadi fokus penelitian ini. Studi ini bertujuan untuk mengekplorasi pengaruh dan dampak musik ansambel terhadap pengalaman ibadah jemaat. Metode penilitian melibatkan observasi langsung selama ibadah dan wawancara dengan anggota ansambel serta jemaat. Temuan menunjukan bahwa penampilan ansambel menciptakan atmosfer spritual yang mendalam, meningkatkan keterlibatan jemaat dan memberikan konstribusi positif terhadap kehidupan ibadah. Implikasi praktis dari penelitian ini dapat menjadi landasan untuk pengembangan lebih lanjut dalam pengelolaan dan pelayanan musik di lingkungan gereja.abstract The ensemble performance at the west Betlehem Oesapa Congregation is the focus of this research. This study aims to explore the influence and impact of ensemble music on the congregation. Findings indicate that ensembel performance create a deeply spiritual atmosphere, increase congregational engagement, and make positive contributions to worship life. The practical impications of this research can be a basis for further development in the management and ministry of music in the chruch environmet.
Pubertal Timing Mediates the Association Between Threat Adversity and Psychopathology
Authors: Shaul Michelle , Whittle Sarah , Silk Tim , Vijayakumar Nandita
Published: December 2023

Background: Exposure to adversity in childhood is a risk factor for lifetime mental health problems. Altered pace of biological ageing, as measured through pubertal timing, is one potential explanatory mechanism for this risk. This study examined whether pubertal timing mediated the association between adversity (threat and deprivation) and adolescent mental health problems (internalizing and externalizing), and whether this was moderated by sex. Methods: Aims were examined using the Adolescent Brain and Cognitive Development Study, a large population representative sample from the United States. Data was used from three timepoints across the ages of 9- to 14- years. Latent scores from confirmatory factor analysis operationalized exposure to threat and deprivation. Bayesian mixed-effects regression models tested whether pubertal timing in early adolescence mediated the effects of adversity exposure on later internalizing and externalizing problems. Sex was examined as a potential moderator of this pathway. Results: Both threat and deprivation were associated with later internalizing and externalizing symptoms. Threat, but not deprivation, was associated with earlier pubertal timing, which mediated the association with internalizing and externalizing problems. Sex differences were only observed in the direct association between adversity and internalizing problems, but no such differences were present for mediating pathways. Conclusions: Adversity exposure had similar effects on the pace of biological ageing (as indexed by pubertal timing) and mental health problems in males and females. However, the impact of adversity on pubertal timing appears to depend on the dimension of adversity experienced, with only threat increasing risk of earlier pubertal timing.
Welche Präkonzepte besitzen Grundschullehramtsstudierende zu Nachhaltigkeit und nachhaltiger Entwicklung und (wie) verändern sich diese über ein Seminar zum Thema BNE hinweg?
Authors: Baumann Rebecca , Meyer Simon , Bärtlein Lotta , Martschinke Sabine
Published: December 2023

Eingebettet in das Projekt BNEprimus wird mit dem Beitrag eine Seminarkonzeption zu „Bildung für nachhaltige Entwicklung (BNE) in der Grundschule“ beschrieben. Zudem werden durch die Erhebung von Prä- und Postkonzepten zu Nachhaltigkeit bzw. nachhaltiger Entwicklung Lernprozesse mit dem Ziel der Professionalisierung bei Grundschullehramtsstudierenden (N = 76) mit Kontrollgruppendesign evaluiert. Die Prä- und Postkonzepte vor und nach Seminarteilnahme werden in Fragebögen mit offenem Antwortformat erhoben, mit qualitativer Inhaltsanalyse ausgewertet und quantifiziert. Nur bei der BNE-Seminargruppe liegt nach der Teilnahme ein umfänglicheres und differenzierteres Begriffsverständnis zur BNE vor, woraus sich erste Hinweise auf erworbene Fachkonzepte und vernetztes Professionswissen ableiten lassen.
Nanomaterials Function in Additive Manufacturing
Authors: Hossain Khan Rajib , Shyeed Md. Abu , Amin Md Al , Hossain Md. Samrat , Rahman Md. Saidur , Rahman Md. Habibur , Nasreen Channa
Published: December 2023

Nanomaterials are substances that have at least one dimension that falls within the three-dimensional nanoscale range or fundamental structural components made of substances that fall inside this range. Micro-nano 3D printing technology can realize the processing of 3D micro-nano structures with nanometer precision and has broad application prospects in many fields. Metals and polymers can be easily connected through bonding reactions to obtain metal-metal or covalent bonds in 3D printing. These potent chemical bonds make 3D-printed structures stable, and 3D printing of metals and plastics is developing rapidly. The review focuses on the latest developments in unique composite nanomaterials for different field applications, comprising nanomaterials and 3D printing technology. A summary of the mechanisms, functional characteristics, benefits, drawbacks, and applications of various nanomaterials used in scientific 3D printing includes metal-based nanomaterials, metal-organic frameworks, upconversion nanoparticles, and lipid-based nanoparticles. Finally, this study presents an overview and highlights the issues that need to be resolved for nanomaterials to continue to be developed for the advantages of 3D printing.
Моделирующее представление одного истребительного сюжета из ТаНаХа (Изэвель)
Authors: Czerwiński Piotr
Published: December 2023

Podstawę analizy stanowi tu znany z Pisma Świętego wątek, na podstawie którego Izebel — żona siódmego władcy północnego Królestwa Izraela Achaba — czcicielka Baala i Astarte (Aszejry) najpierw eliminuje proroków Bożych, a następnie poprzez intrygę i fałszywe donosy doprowadza do ukamienowania Nabota, aby Achab mógł po nim odziedziczyć upragnioną winnicę. Wydarzenia te w konsekwencji doprowadzają — zgodnie z przepowiednią proroka Eliasza — do zagłady samej Izebel. Zawarte w tekście źródłowym dane pozwoliły wyróżnić i opisać trzy kolejno następujące i powiązane ze sobą modele: ukierunkowanego wykonania („Zrobię z tobą / z twoim to, co ty ze mną / z moim uczyniłeś”), pozyskania poprzez podmianę (wątek z zabójstwem Nabota), przepowiedzianego unicestwienia (morderstwo Izebel i wyrzucenie jej przez okno). Wspólną podstawą jest tu wyrządzanie zła, które prowadzi do nieuniknionej konsekwencji, polegającej w tym przypadku na całkowitej eliminacji, unicestwieniu tego, kto owo zło wyrządził. Wyróżnianym tu modelom towarzyszą charakterystyka ról uczestników, opis cech semantycznych i schematy predykatywno-składnikowe. Autor wyciąga wnioski na temat możliwości podobnego ujęcia rozwijających się wątków w tekstach tradycyjnych.
Tόπος versus אוטופיה: опыты поэтического осмысления места на русском языке в Израиле конца 20-го века
Authors: Singer Nekoda
Published: December 2023

Статья рассматривает проблему места на примере творчества 8-и русскоязычных поэтов Израиля
МАТЕМАТИЧНЕ МОДЕЛЮВАННЯ БАЗОВИХ ПАРАМЕТРІВ СТЕРЖНЕВОГО ЗАВАНТАЖЕННЯ ЦИЛІНДРИЧНИХ МЛИНІВ ЯК КЕРОВАНИХ ОБ’ЄКТІВ
Authors: В.О. Кондратець , А.М. Мацуй , О.М. Сербул
Published: December 2023

Виокремлено параметри стержневого завантаження, ролі яких приділялося мало уваги. Серед них — об’єм пустот для розміщення руди, імпульс ударного стиснення, класифікуюча властивість стержневого завантаження. Дослідження виконані в межах розробки теми «Оптимізація продуктивності стержневих млинів розімкнутого циклу по руді і готовому продукту при мінімальних енергетичних і матеріальних перевитратах», яка є складовою наукової тематики Центральноукраїнського національного технічного університету. Тема статті актуальна. Метою роботи є встановлення базових параметрів стержневого завантаження млинів як керованих об’єктів. Застосовані методи аналізу, порівняння, математичного і геометричного моделювання, методи теорії подрібнення руди в стержневих млинах, композиції, метод імпульсу ударного стиснення, метод кінетики подрібнення руди в млинах. Відмічено, що стержневі млини досягли свого найбільшого розміру (в Україні 4,5×6,0 м), який більше зростати не буде. Для стержневих млинів найбільш сприятливим є каскадний режим роботи, при якому руда руйнується роздавлюванням і стиранням. Використовується багаторозмірне стержньове середовище з 3—4 діаметрами стержнів. У стержневому завантаженні поздовжня сегрегація молольних тіл виникнути не може. Поперечна сегрегація аналогічна кульовому завантаженню. Дрібні стержні відтісняються до стінки барабана, а крупні накопичуються в центральних областях. Витрата стержнів складає 0,12 кг/кВт×г корисно витраченої енергії. Звичайно довантаження стержнів на заміну спрацьованих здійснюють через кожні 5 діб, а перекласифікацію — через кожні 10 діб. Видаляють стержні з барабана млина при спрацюванні до 15—25 мм. Стержневі млини подрібнюють вихідну руду в основному від 25 мм до 2 мм при вмісті твердого в пульпі 84—86 %. Однорозмірні стержні зберігають стійке положення в процесі подрібнення завдяки розпираючому впливу руди між ними. В такому стані в стержневому завантаженні розміщується 21,5 % руди. У кульовому однорозмірному завантаженні цей показник складає 26 %. У стержневих млинах молольне середовище формується обширними зонами з стержнями наближено однакового діаметра, що дозволяє його розглядати як однорозмірне. Його імпульс ударного стиснення складає 14,026, що на 28,3 % вище порівняно з найкращими показниками кульових млинів. Показано, що стержневий млин, виконуючи крупне, середнє і дрібне подрібнення, володіє класифікуючою здатністю. Встановлені параметри стержневого завантаження дозволяють будувати більш ефективні автоматизовані системи керування подрібненням руди в розімкнутих циклах.
МОДЕЛЮВАННЯ БУДОВИ КАРБІДА ХРОМУ ПРИ ДОСЛІДЖЕННІ АМОРФНИХ СПЛАВІВ
Authors: І.В. Кругляк , О.С. Баскевич , О.М. Гуливець , О.П. Максименко
Published: December 2023

У роботі розглядаються теоретичні аспекти моделювання аморфних і нанокристалічних сплавів перехідних металів і металоїдів. Проведено моделювання близького порядку аморфних сплавів Cr–C, які отримані методом електроосадження, в залежності від густини струму та температури електроліту. Встановлено залежність між умовами отримання та близьким порядком аморфних сплавів. Розроблено методику розшифровки функції радіального розподілу атомів (ФРРА) на основі концепції кластерної структури аморфних металів. Проведено моделювання близького порядку аморфних сплавів Cr–C з використанням апроксимації піків ФРРА атомів, що характерні для аморфного сплаву Ni86P14. Досліджено структуру електроосаджених осадів Cr–C за різних значень густини струму та температур електроліту. Встановлено, що структура матеріалу є аморфною, а розміри орієнтованих випадкових областей (ОВРА) змінюються в межах від 3,6 до 5 нм. Параметри решітки зразків незначно збільшуються, що пов'язано зі зміною кількості карбону. Об'єм осаду складається з ОВРА, форма яких наближена до кубооктаедрів, а об'ємна частка зменшується зі збільшенням температури електроліту.
Entry-to-Practice Business and Practice Management Competencies: A Qualitative Systematic Review to Inform Canadian Physiotherapy Curricula
Authors: Coward Corey , Hunter Josh , Halliday Sandra M. , Jeffers Brendy , Hopkins-Rosseel Diana
Published: December 2023

Purpose:

There is increasing demand for business skills among healthcare professionals. The aim of this qualitative systematic review was to identify and summarize existing business and practice management (BPM) competencies for rehabilitation university graduates with the intention to inform curricula.

Method:

The key electronic databases searched include ABI/INFORM Global, CINAHL, Education Source, Embase, and Medline. The initial search was performed in December 2018 and updated June 2021 with the following inclusion criteria: articles addressing BMP competencies in university-level rehabilitation programs in developed countries. To ensure professional position statements and standards documents were captured, this grey literature was also included. Resources were extracted using EndNote and two reviewers independently screened and appraised the resources using the AACODS Checklist.

Results:

Nine resources met the inclusion criteria and were incorporated in the qualitative synthesis. Quality-assessment scores ranged from 4 to 6 out of 6 on the AACODS Checklist. Several practice management competencies were consistent across multiple rehabilitation professions. However, business competencies were inconsistent with “marketing” and the “ability to develop a business plan” arising sporadically across Occupational Therapy and Physiotherapy competency profiles, as well as individual audiology courses.

Conclusion:

There is insufficient evidence to suggest that a consensus exists for BPM competencies for rehabilitation university graduates in Canada. The aggregate list of 64 competencies compiled can be used to inform further research.
Serum S100P and C4d proteins as markers for active proliferative lupus nephritis in Egyptian patients with systemic lupus erythematosus
Authors: Elnokeety Mahmoud M. , Khalil Noha , Fayed Ahmed
Published: December 2023

Lupus nephritis (LN), occurring in approximately 50% of individuals with systemic lupus erythematosus (SLE), significantly influences therapy and prognosis. Proliferative LN, more prevalent than non-proliferative LN, is associated with a poorer prognosis. This study aimed to investigate the potential correlation between serum levels of the pro-inflammatory proteins human calcium-binding S100P (S100P) and Human complement Fragment 4 (C4d) and confirmed proliferative LN through biopsy. The objective was to evaluate their reliability as biomarkers for disease activity in proliferative LN.

Methods. Serum S100P and C4d were measured using enzyme-linked immunosorbent assay in 100 female patients with established SLE. Among these, 50 had confirmed proliferative LN through biopsy, and 50 did not. A control group of 50 healthy female donors' plasma samples was included.

Results. SLE patients with proliferative LN exhibited significantly higher serum levels of S100P (P < 0.001) and C4d (P < 0.001) compared to SLE patients without LN and controls. Serum S100P demonstrated a significantly higher positive correlation with the activity index in renal biopsies (r = 0.784) compared to serum C4d (r = 0.416). Additionally, serum S100P had a significantly higher positive correlation with SLEDAI-R than serum C4d (r = 0.651 vs. r = 0.257). Both serum S100P and C4d showed promise as reliable biomarkers for the diagnosis of active proliferative LN, as indicated by the ROC curve and AUC assessments.

Conclusion. Serum concentrations of S100P and C4d emerge as useful indicators for identifying SLE patients with active proliferative LN.
EDUCATION FOR SUSTAINABLE DEVELOPMENT IN GEOGRAPHY TEACHING ON THE BASIS OF COMPETENCE-BASED APPROACH
Authors: Shukanova Anzhela , Shukanov Pavlo , Braslavska Oksana
Published: December 2023

The article analyzes the possibilities of implementing a competency-based approach to education for sustainable development in the process of teaching geography. The authors summarize UNESCOʼs approach to the formulation of the objectives of education for sustainable development, which are the formation of key interdisciplinary competencies and special competencies. Among the key competencies are the following: systemic thinking; prognostic; regulatory; strategic and innovative; teamwork; critical thinking; self-awareness; and integrated problem solving. Special competencies take into account the specifics and context of each of the 17 global sustainable development goals and are divided into educational, cognitive, socio-emotional and behavioral components. A contextual analysis of geography programs in general secondary education has shown that school geography has the best conditions for incorporating sustainable development ideas into the educational process. The cross-cutting content area “Environmental Safety and Sustainable Development” in the primary school geography course focuses geography teachers mainly on the formation of knowledge about sustainable development, to a lesser extent on the formation of behavior adequate to the principles of sustainable development (behavioral and activity component), and in general, insufficient attention is paid to the emotional and value component. Sustainable development issues are most fully covered in the content of the 9th and 11th grade geography curricula, which complete the geographic education of students in primary and high school. The survey of geography teachers of the Poltava amalgamated territorial community showed a high level of understanding of the essence of education for sustainable development and its differences from environmental education, insufficient coverage in the content of school geography textbooks, the need to encourage geography teachers to receive professional training in the context of sustainable development and to increase their motivation to implement a school-wide approach to the implementation of education for sustainable development.

Keywords: education; sustainable development; competence approach; teaching geography; environmental education; competence; components of education; special competences for sustainable development.