bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness and Safety of Basal Insulin Therapy in Type 2 Diabetes Mellitus Patients With or Without Metformin Observed in a National Cohort in China
Authors: Zhang Puhong , Zhang Heng , Luo Yingying , Zhu Dongshan , Li Xian , Ji Jiachao , Chen Minyuan , Wang Du , Ji Linong
Published: February 2021

Background.

Though many randomized control trials had examined the effectiveness and safety of taking insulin therapy with or without metformin, there are limited real-world data, especially among Chinese type 2 diabetes patients initiating basal insulin (BI) with uncontrolled hyperglycemia by oral agents. This study was designed to assess the effectiveness and safety of BI therapy combined with or without metformin in a real-world national cohort study.
Methods.

Patients with type 2 diabetes mellitus who initiated BI treatment due to uncontrolled hyperglycemia (HbA1c ≥ 7%) by oral antidiabetic drugs (OADs) were recruited in Chinese real-world settings between 2011 and 2013. A total of 12,358 patients initiated BI without bolus insulin and completed a 6-month follow-up were selected as the study population and divided into BI with metformin or BI without metformin group based on whether metformin was simultaneously prescribed or not at baseline. Propensity score adjustment was used to balance baseline covariates between two groups. A sub-analysis was also conducted among 8,086 patients who kept baseline treatment regimen during the follow-up. Outcomes were HbA1c, hypoglycemia, weight gain and insulin dose in two groups.
Results.

53.6% (6,621 out of 12,358) patients initiated BI therapy concomitant with metformin. After propensity score adjustment, multivariate regression analysis controlled with number of OADs, total insulin dose, physical activity and diet consumption showed that BI with metformin group had a slightly higher control rate of HbA1c < 7.0% (39.9% vs. 36.4%, P = 0.0011) at 6-month follow-up, and lower dose increment from baseline to 6-month (0.0064 vs. 0.0068 U/day/kg, P = 0.0035). The sub-analysis with patients remained at same BI therapy further showed that BI with metformin group had higher HbA1c control rate (47.9% vs. 41.9%, P = 0.0001), less weight gain (-0.12 vs 0.15 kg P = 0.0013), and lower dose increment during 6-month follow-up (0.0033 vs. 0.0037 U/day/kg, P = 0.0073) when compared with BI without metformin group.
Conclusion.

In alliance with current guidelines, the real-world findings also support the insulin initiation together with metformin. Continuous patients’ education and clinicians training are needed to improve the use of metformin when initiating BI treatment.
Soil microbial community responding to moderately elevated nitrogen deposition in a Japanese cool temperate forest surrounded by fertilized grasslands
Authors: Nagano Hirohiko , Nakayama Masataka , Katata Genki , Fukushima Keitaro , Yamaguchi Takashi , Watanabe Makoto , Kondo Toshiaki , Atarashi-Andoh Mariko , Kubota Tomohiro , Tateno Ryunosuke , Koarashi Jun
Published: February 2021

In order to examine the hypothesis that the soil microbial community in a nitrogen-limited forest responds to moderately elevated nitrogen deposition (< 10kg N ha-1 yr-1), correlations between nitrogen deposition and soil microbial properties were analyzed in a cool temperate forest surrounded by normally fertilized pasture grasslands in northern Japan. Three experimental plots were established in forest edges adjacent to the grasslands and the other three plots were in forest interiors at least 700 m away from the grasslands. Nitrogen deposition in each plot was measured from May to November 2018. In August 2018, litter and surface soil samples were collected from all plots to measure net nitrogen mineralization and nitrification rates as indicators of microbial activity, and microbial biomass and various gene abundances (i.e., bacterial 16S rRNA, fungal ITS, and bacterial and archaeal amoA genes) as indicators of microbial abundance. Nitrogen deposition in forest edges was 1.4-fold greater than that in forest interiors, whereas maximum deposition was 3.7 kg N ha−1. Nitrogen deposition was significantly correlated with net nitrogen mineralization and nitrification rates and 16S rRNA and bacterial amoA gene abundances. Microbial community structures analyzed for bacterial 16S rRNA and fungal ITS gene amplicons were different between litter and soil samples, but were similar between the forest edge and interior. Nitrogen deposition was also correlated with the soil carbon-to-nitrogen ratio and nitrate and ammonium contents. Thus, it was suggested that some soil microbial activities and abundances in a nitrogen-limited forest likely responded to moderately elevated nitrogen deposition. These findings provide primary information on soil microbial response to moderately elevated nitrogen deposition.
Consequences of exposure to prenatal famine on estimated glomerular filtration rate and risk of chronic kidney disease among survivors of the great Ethiopian famine (1983-85): a historical cohort study
Authors: Abate Kalkidan Hassen , Abdulahi Misra , Abdulhay Fedlu , Arage Getachew , Abafogi Mohammed Mecha , Yenuss Mohammed , Hassen Habtamu , Belachew Tefera
Published: February 2021

Background: The impact of an adverse prenatal environment such as famine exposure on the development of adulthood non-communicable chronic illnesses, including diabetes and hypertension has been well articulated in the recent past and supported by evidence. However, there exist few longitudinal studies conducted on the long term consequences of prenatal famine exposure on adulthood kidney function. Hence, we set out to examine whether prenatal exposure to the Ethiopian Great Famine (1983–1985) was associated with changes in estimated glomerular filtration rate (eGFR) and the risk of developing chronic kidney disease (CKD) later in adult life.Methods: The study was conducted in 219 famine exposed and 222 non exposed cohorts in Raya Kobo district, North Wollo Zone, Northern Ethiopia. Estimated GFR was computed from standardized serum creatinine using the CKD Epidemiology Collaboration (CKD-EPI) equation. The definition of CKD includes those with an eGFR of less than 60 ml/min/1.73m2 on at least in two occasions of ninety days apart (with or without markers of kidney damage). Linear and logistic regression analyses were employed to examine the independent effect of prenatal famine exposure on eGFR and CKD respectively.Results: The mean (SD) serum creatinine of exposed and non-exposed groups were 0.78 (0.2) and 0.75 (0.2) respectively. The mean (SD) eGFR of exposed groups was 107.95 (27.49) while the non-exposed 114.48 (24.81) ml/min. In linear regression, the unadjusted model to examine the association between famine exposure and eGFR resulted in a significant negative beta coefficient (β = -0.124: 95% CI: -11.43, -1.64). Adjusting the exposure for outstanding covariates of kidney health, including systolic blood pressure, fasting blood sugar and blood glucose did not alter the inverse relationship (β = -.114 95% CI: -10.84, -1.17). In the unadjusted bivariate logistic regression model, famine exposure resulted in nearly 2.7 times higher odds of developing CKD (OR: 2.68, 95% CI: 1.16, 6.2). The odds remained equivalent after adjusting for systolic blood pressure, fasting blood glucose and body mass index (OR= 2.61: 95% CI: 1.120, 6.09).Conclusion: In the study setting, prenatal exposure to the Great Ethiopian Famine was associated with decreased eGFR and higher risk of developing CKD among survivors. These findings may imply that famine in early life may play a significant role in the development of kidney dysfunction in adulthood.
Cross-cultural Adaptation, Validity and Reliability of the Chinese Version of Miller Behavioral Style Scale
Authors: Zhuo Qiqi , Cui Changsheng , Liang Hongmin , Bai Yangjuan , Hu Qiulan , Hanum Ardani Latifah , Yang MingFang , Wang Yanjiao , Wei Wei , Ding Lan , Ma Fang
Published: February 2021

Background: Health education basing on patients’ information-seeking styles can improve the effectiveness of health education and patients’ health outcomes. The Miller Behavioral Style Scale (MBSS) is widely used to identify individual’s information-seeking styles, but the Chinese version is lacking. The study aim was to translate and culturally adapt the MBSS into Chinese version and test the content validity, construct validity and internal consistency reliability of the Chinese version of MBSS (C-MBSS).Methods: The forward-back-translation procedure was adopted in the translation of the MBSS. Content validity was assessed in a panel of experts. In a sample of 1343 individuals including patients, patients’ caregivers, university students, and medical staff, reliability and construct validity were assessed using Cronbach’s alpha coefficient and factor analysis. The measurement invariance across samples was tested using multigroup confirmatory factor analysis (MGCFA). Floor and ceiling effects were checked.Results: The C-MBSS achieved conceptual and semantic equivalence with the original scale. The item-level content validity index (I-CVI) of each item ranged from 0.78 to 1, and the averaging scale-level content validity index (S-CVI/ Ave) was 0.95. The exploratory factor analysis resulted in 2-factor assumption for each hypothetical threat-evoking scenario. Confirmatory factor analysis demonstrated a good fit between theoretical model and data, which provided confirmatory evidence for the second-order factor structure of 2-factor solution (Monitoring and Blunting). The Cronbach's alpha coefficients for the Monitoring and Blunting sub-scales of the C-MBSS were 0.75 and 0.62 respectively. MGCFA results supported the measurement invariance for the Monitoring sub-scale of the C-MBSS across samples. No floor or ceiling effects occurred. Conclusions: This study indicates that the C-MBSS has good content and construct validity. The Monitoring sub-scale of the C-MBSS had acceptable internal consistency reliability while the Blunting sub-scale had unsatisfactory one, which suggest that the Monitoring sub-scale of the C-MBSS can be used to identify individuals’ information-seeking styles in Chinese contexts across different populations.
Prognostic Marker for Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Analysis of Diffusing Capacity of the Lung for Carbon Monoxide (DLCO) and Forced Expiratory Volume in One Second (FEV1)
Authors: Choi Juwhan , Sim Jae Kyeom , Oh Jee Youn , Lee Young Seok , Hur Gyu Young , Lee Sung Yong , Shim Jae Jeong , Rhee Chin Kook , Min Kyung Hoon
Published: February 2021

Background: It is important to assess the prognosis and classify patients in chronic obstructive pulmonary disease (COPD) and acute exacerbation of COPD (AECOPD) treatment. Recently, it was suggested that diffusing capacity of the lung for carbon monoxide (DLCO) should be added to multidimensional tools for assessing COPD. This study aimed to compare the DLCO and forced expiratory volume in one second (FEV1) to identify better prognostic factors for admitted patients with AECOPD.Methods: We retrospectively analyzed 342 patients with AECOPD receiving inpatient treatment. We classified 342 severe AECOPD events using DLCO and FEV1. We defined the prognostic factors of severe AECOPD as the length of hospital stay, mortality in hospital, experience of mechanical ventilation, and experience of intensive care unit (ICU) care. We analyzed the prognostic factors by multivariate analysis using logistic regression. In addition, we conducted a correlation analysis and receiver operating characteristic (ROC) curve analysis.Results: In univariate and multivariate analyses, DLCO was shown to predict mortality rate (odds ratio = 4.408; 95% confidence interval, 1.070–18.167; P = 0.040), experience of ventilator (odds ratio = 2.855; 95% confidence interval, 1.216–6.704; P = 0.016) and ICU (odds ratios = 2.685; 95% confidence interval, 1.290–5.590; P = 0.008). However, there was no statistically significant difference in mortality rate when using FEV1 classification (P = 0.075). In the correlation analysis, both DLCO and FEV1 showed a negative correlation with length of hospital stay. The correlation rate was more pronounced in the DLCO (DLCO; B = -0.103, P < 0.001) (FEV1; B = -0.075, P = 0.007). In addition, DLCO showed better predictive ability than FEV1 in ROC curve analysis. The area under the curve (AUC) of DLCO was greater than 0.68 for all prognostic factors, and in contrast, the AUC of FEV1 was less than 0.68.Conclusion: DLCO was likely to be as good as or better prognostic marker than FEV1 in severe AECOPD.
Traditional use of medicinal plants in the Chyangthapu-Phalaicha biological sub-corridor, Panchthar District, Kangchenjunga Landscape, Nepal
Authors: Bhandari Prabin , Gurung Min Bahadur , Subedi Chandra Kanta , Chaudhary Ram Prasad , Basnet Khadga , Gurung Janita , Uprety Yadav , Neupane Ajay , Shrestha Krishna Kumar
Published: February 2021

Background: Chyangthapu-Phalaicha located in the northeastern Panchthar District, is a biodiversity hotspot in the Eastern Himalaya. The area is dominated by the Kirat indigenous community. The present study was conducted to document the knowledge of the ethnomedicinal uses and practices that exist in the area before the associated socio-cultural knowledge on biological diversity is lost. Methods: Ethnomedicinal data were collected through semi-structured questionnaires. Stakeholders meetings were organized for assessing the conservation issues in the sub-corridor. The importance of medicinal plant species was assessed using quantitative indices such as informant consensus factor, relative frequency of citation, relative importance, fidelity level and Rahman’s similarity index. Results: Altogether, 140 medicinal plant species from 68 families and 127 genera were reported, which were used to treat 12 health disorders categories. The dominant families were Asteraceae and Fabaceae which contributed eight species each. Fifty-five percent of the total medicinal plant species comprised of herbs. The most frequently used plant parts were underground parts (33%) and leaf (15%). The most common remedies preparation method was extract. Oral administration was the most common therapeutic mode (60%). Maximum informant consensus factor (0.96) was calculated for gastrointestinal disorders. The highest relative frequency of citation and fidelity level was observed for Swertia chirayita (0.83 and 100% respectively). Artemisia dubia depicted the highest relative importance (91.67). A thorough review of previous literature and analysis of field data revealed new therapeutic use reports for 41 ailments associated with 52 plant species. The Rahman similarity index was high with the studies in neighbouring areas, while it was low with the geographically distant studies. Conclusions: The ethnomedicinal study of the Chyangthapu-Phalaicha biological sub-corridor in the Kangchenjunga Landscape indicates that the area supports significant medicinal plants and associated traditional knowledge. The varied use of reported medicinal plants in the area indicates the need for their domestication, processing and phytochemical investigation, especially for those with high ethnobotanical indices.
PRELIMINARY ETHNOBOTANIC STUDY OF PLANTS USED TO TREAT INFANT DIARRHEA BY THE MITSOGHO PEOPLE IN GABON
Authors:   Departement de Biologie et dEcologie Vegetale. Institut de Recherche en Ecologie Tropicale (IRET), Gabon., Mboma Raymonde , Grace Ombouma Joanna ,   Departement de Pharmacologie. Faculte de Pharmacie. Universite des Sciences de la Sante, B.P 4009 Libreville-Gabon., Akendengue Blandine ,   Departement de Pharmacologie. Faculte de Pharmacie. Universite des Sciences de la Sante, B.P 4009 Libreville-Gabon., G. Houngbeme Alban ,   Laboratoire de Pharmacognosie/Institut de Recherche et dExperimentation en Medecine et Pharmacopee Traditionnelles (IREMPT)/Centre Beninois de la Recherche Scientifique et de lInnovation (CBRSI) /UAC, 01 BP 06 Oganla Porto-Novo, Benin., R.B. Houinato Marcel ,   Faculte des Sciences Agronomiques de lUniversite dAbomey-Calavi, 01 BP 526 Cotonou, Benin., A. Gbaguidi Fernand ,   Laboratoire de Pharmacognosie/Institut de Recherche et dExperimentation en Medecine et Pharmacopee Traditionnelles (IREMPT)/Centre Beninois de la Recherche Scientifique et de lInnovation (CBRSI) /UAC, 01 BP 06 Oganla Porto-Novo, Benin.,   Laboratoire de Chimie Pharmaceutique Organique, Ecole de Pharmacie, Faculte des Sciences de la Sante, Universite dAbomey-Calavi, Campus du Champ de Foire, 01 BP 188, Cotonou, Benin.
Published: February 2021

An ethnobotanical study of medicinal plants was carried out among the Mitsogho people of thefour (4) villages located from Oyane 4 to Four-Place (Estuaire-Gabon). The objective of this study was firsttodraw up an inventory of plants used in their traditional medicine against infant diarrhea and then to describe the recipes applied by the local population. Sixteen (16) plants species belonging to sixteen (16) genus and eleven (11) families were identified. The most species cited were Sida rhombifolia (18%), Cyathula prostrata (12%), Desmodium adscendens (12%), andPsidium guineense (12%). Those with the lowest frequencies were among others Picralima nitida (6%) and Santiria trimera (6%). The most represented families are Malvaceae (25%), Apocynaceae (12.5%) and Fabaceae (12.5%). The plants inventoried are mainly woody (81%) trunk bark (56%) and leaves (37%) are the most used plant parts. Twenty-two (22) recipes have been described, of which 77% contain a single plant and 23% are mixture.
The clinical course of bartonellosis in 24 cats
Authors: MAZUREK ŁUKASZ , TEODOROWSKI OLIWIER , DĘBIAK PIOTR , SZCZEPANIAK KLAUDIUSZ , WILCZYŃSKA ANNA , WINIARCZYK STANISŁAW , ADASZEK ŁUKASZ
Published: February 2021

The aim of this study was to analyse clinical cases of bartonellosis. Medical records of cats naturally infected with Bartonella henselae were retrospectively evaluated with regard to clinical signs and laboratory abnormalities at the time of presentation, therapy and course of disease. The most common clinical abnormalities in B. henselae-positive cats included in the study were flea allergic dermatitis (29.5%), fever (25%) and diarrhoea (12.5%). Thrombocytopenia was the most common laboratory abnormality (50%).The results of the study indicate that B. henselae infection must be considered in differential diagnosis in patients with thrombocytopenia and flea invasion.
Decomposing drivers of changes in productive and domestic water use based on the logarithmic mean Divisia index method: a regional comparison in Northern China
Authors: Lyu Wenfei , Chen Yuansheng , Yu Zhigang , Yao Weiwei , Liu Huaxian
Published: February 2021

It is crucial to consider regional heterogeneity while analyzing drivers of changes in sectoral water use for developing differentiated and effective demand-regulation strategies in China. By using the logarithmic mean Divisia index method, this study compares dynamic influences of intensity, structure and scale factors on changes in productive and domestic water use during 2003–2017 between Tianjin (a socio-economic developed region) and Hebei (less-developed). The results show that the scale effect stimulated the growth of productive water use in both regions, while structure and intensity effects restrained such growth. The three effects all stimulated the growth of domestic water use in most years in both regions. In both regions, the largest contributor to changes in productive and domestic water use was the scale and intensity effect, respectively. However, in the two regions, the synergies of three effects resulted in different change trends of productive water use, and cumulative contributions of sub-sectors to the intensity, structure and scale effects were not exactly the same. Tianjin and Hebei need to keep on adjusting industrial structure and lowering water-use intensity to control future growth of productive water use and take strict measures to tackle the increasing trend of domestic water use but should have different policy implementation focuses.
The impact of COVID-19 on households’ water use in Uganda
Authors: Sempewo Jotham Ivan , Mushomi John , Tumutungire Martin Dahlin , Ekyalimpa Ronald , Kisaakye Peter
Published: February 2021

The unprecedented outbreak of COVID-19 necessitated the promotion of better hygiene practices to curb the spread of the virus. Better hygiene requires that households have a stable supply of water. However, little is known about the predictors of changes in water use in emergency situations such as COVID-19 in Uganda. This study uses data from a cross-sectional survey to examine the changes in the quantities of water used by 1,639 Ugandan households due to COVID-19. This article also explores the factors that are associated with changes in water use. The month March 2020 is used in this study as a cut-off because this is the month in which the government implemented a lockdown to curb the spread of the virus. Results indicate that most households had an increase in the quantity of water used after March 2020 when compared with the period before March 2020. Household characteristics that were associated with a change in the quantity of water used were age, sex, education, main occupation of household head, household size and region of residence. The results can be used to inform the prediction and demand modelling of household water use for improved water interventions for equitable water supply during emergencies.
Behaviour of Precast Concrete Beam-to-Column Connection with SHS Hidden Corbel Subjected to Monotonic Load
Authors: Ling Jen Hua , Lim Jee Hock , Abd Rahman Ahmad Baharuddin
Published: February 2021

Beam-to-column connection is the most critical part of a precast concrete (PC) structure as it governs the integrity of the entire structure. In this study, a beam-to-column connection with square hollow section (SHS) hidden corbel was developed. A full-scale test was conducted on eleven T-subframe specimens with various configurations to investigate the behaviour of the connection under an incremental static load. The behaviour of the connection was evaluated in terms of the moment-rotation response and the mechanical properties were obtained by using the beam-line method. Due to the extensive usage of steel elements, the PC connect possessed a higher ultimate strength than the reinforced concrete (RC) connection. The moment resistance of the connection was largely contributed to by the hidden corbel embedded in the beam and column. However, the PC connection gave a lower stiffness, which resulted in a larger rotation deformation than the RC connection, and thus lowered its design strength. The PC connection was classified as semi-rigid and partial strength, and only specimen PC-3 was considered feasible for PC structures.
Фотографии артефактов монгольского цама, сделанные чехословацкими исследователями в 1950-х и 1960-х гг.: новый взгляд на старые документы
Authors:   Charles University (1/2,  nám. J. Palacha, 116 38 Praha 1, Czech Republic), Kapišovská Veronika V.
Published: February 2021

Introduction. This paper deals with two sets of colour photographs of Mongolian tsam masks taken by Czechoslovak archaeologist Lumír Jisl (1921–1969) and art photographer Werner Forman (1921–2010) in Mongolia during the period of 1956–1963. Werner Formanʼs photographs appeared in Lamaistische Tanzmasken. This unpretentious, slim volume, with a text composed by B. Rinchen (with the apparent assistance of a former tsam ceremony master, giving it unequivocal authenticity) holds a unique position: it was published 32 years after the last eye-witness description of the Mongolian tsam given by Shastina in 1935 (including black-and-white photographs), and some two decades before the series of tsam mask photographs featured in Tsultemʼs Mongolian Sculpture and Iskusstvo Mongolii ʻMongolian Artʼ. In contrast, Lumír Jislʼs photographs, apart from the few that were published during his lifetime, were preserved in a family archive for more than fifty years. The goal of this paper is to describe the circumstances under which these colour photographs came into being. A brief account is given of the visits to Mongolia undertaken by Lumír Jisl and Werner Forman. The general background of Czechoslovak-Mongolian cooperation in its first decade after the establishment of diplomatic relations between the two countries is also sketched out. At that time, tsam masks were stored in the Choijin Lama Temple, one of the very few monastic complexes to survive the antireligious campaign of the late 1930s; the temple became shelter to many religious artefacts. In addition to photographing this temple complex, Lumír Jisl photographed the tsam masks during research trips to at least three regional museums. This paper also describes the different goals and visions of both Lumír Jisl and Werner Forman when photographing the tsam masks, resulting in differing modes of execution. In conclusion, I examine the changes in perspective of the Buddhist monks following the general atmosphere of mistrust and fear engendered by the antireligion campaigns and repressions of the late 1930s, as well as the subsequent partial easing of these repressions. Not only were Forman and Jisl both invited to take photographs of religious artefacts, but they also received assistance in doing so. The Mongolian monks who helped Forman and Jisl had to accept, however, the drastically changed status of these artefacts: once sacred items used in religious ritual dance, they were now objects of Mongolian artistic heritage.
Семь десятилетий ойратоведения в КНР (1949‒2019 гг.)
Authors:   Institute of Chinese Borderland Studies, Chinese Academy of Social Sciences (1, Goujia tiyu chang beilu, Chaoyang Distr., Beijing 100101, People’s Republic of China), Alatengaoqier Na. , Bicheev Baazr A. ,   Kalmyk Scientific Center of the RAS (8, Ilishkin St., Elista 358000, Russian Federation)
Published: February 2021

Introduction. Historically, the Oirats of China mainly live in the territory of Xinjiang, in the provinces of Qinghai, Gansu, and in the Western part of Inner Mongolia. Some of the Olets (descendants of Dzungars) live in the steppe part of the Emin Gol of the Hulun Buir Aimag of Inner Mongolia, in Fuyu County of Heilongjiang Province, and in Chengdu, Hebei Province. In the modern historical science of China, until the mid-20th century the Oirats were not distinguished from the bulk of China’s Mongols, and, consequently, their history, culture and language were not subjects of individual studies. Only after its formation in 1949, Chinese Oirat studies started gaining visible features as an important part of Mongolian studies and the historical science of China as a whole. At the same time, Oirat studies as a historical direction were created by several generations of scientists of different nationalities (Han Chinese, Mongols, and Oirats themselves). Goals. The article aims to provide a general overview and scientific analysis of the formation and development of Oirat studies in China over the past seven decades (1949–2019), and to identify the historical paradigm of conducted researches and prospects of further development. Methods. The main research method is historical and chronological analysis. Despite Oirat studies have been existing as an integral part of Mongolian science for seven decades, no analysis of its historical development was ever carried out. Results. This work fills the gap and highlights the most important achievements in the study of China-based Oirats’ history and culture. A prominent attention in this study is given to the materials of ten scientific conferences that have the status of ‘all-China’ ones and were devoted to the study of the history and culture of the Oirats, as well as the scientific journal ‘Barayun mongyol sudul’ (‘Journal of Western Mongolian Studies’), which plays an important role in the development and determination of promising areas of Oirat studies. Conclusion. The analysis of Oiratological research over the past seven decades has revealed the historical paradigm of Oirat studies and prospects for their further development.
Стоянка-мастерская Кусимово-6 — памятник эпохи среднего палеолита в Южном Зауралье
Authors:   Institute of History, Language and Literature of the Ufa Federal Research Centre of the RAS (71, Oktyabrya Ave., Ufa  450054, Russian Federation), Kotov Vyacheslav G. , Savelev Nikita S. , Ruslanova Rida R.  ,   National Museum of Bashkortostan (14, Sovetskaya St., Ufa 450077, Russian Federation)
Published: February 2021

In 2019, the workshop site of Kusimovo-6 in Abzelilovsky District of Bashkortostan (Russia) was discovered and explored on a large area. A collection of Middle Paleolithic artifacts numbering over 2 thousand was obtained. Goals. The work attempts at an analysis of the collection. Results. The latter shows its homogeneity. So, nucleuses are subprismatic, with longitudinal cleavages, orthogonal, radial, and of unsystematic types. Many cores have two or more strike platforms. A third of the flakes have natural strike platforms and backrest. The producing of bifacial tools basically repeats the nucleuses’ production patterns. The tools comprise a chopper, 2 blanks of bifaces, 2 taiyak points, a point, butt knives. Two-sided producing was performed on working areas of other categories of tools (carvers, punctures, points, tools with a spike, beak-shaped, notched tools, scrapers). By all indications, the site has a non-Levallois character and belongs to the industry of the Tayacian tradition of the Middle Paleolithic. The workshop site of Kusimovo-6 reveals the greatest similarity with the 3rd and 4th layers (Tayacian industry of the Middle Paleolithic) of the Starye Duruitory Grotto in Northwest Moldova. Accordingly, the workshop site of Kusimovo-6 is dated to the first half of the Rissian period (300-200 thousand years ago).
Development of a Multiplex PCR Assay for Detection and Discrimination of Pathogenic and Saprophytic Leptospira in Water
Authors: Vishwakarma Archana , Rethinavelu Gayathri , Pasupathi Rathinsabapthi , Ramya Mohandass
Published: February 2021

Leptospirosis is a zoonosis prevalent in tropical countries and affects animals and humans alike. Leptospira interrogans, the causative organism for this waterborne infection, spreads through the urine of infected animals. There is a direct link between contaminated water and Leptospira outbreaks. This study reports a rapid assay to detect and differentiate pathogenic Leptospira from non-pathogenic in environmental water using multiplex PCR. The assay uses primers targeting the Lipl32 and Lipl21 gene. The multiplex PCR has been standardized using 11 pathogenic and one saprophytic serovar of Leptospira. The analytical sensitivity of the developed method was evaluated with different concentrations of template DNA. This method was used to screen water samples collected from 20 different sources from Chengalpattu town in Kancheepuram District, Tamil Nadu, India. Of the 20 water samples screened, 13 samples tested positive for pathogenic Leptospira, and seven samples tested negative. Four water samples were found to carry both pathogenic and saprophytic species. The developed multiplex PCR assay is highly useful for detecting and distinguishing pathogenic and saprophytic leptospires in water.
Distribution and Characterization of Actinomycetes in Mangrove Habitats (Red Sea, Egypt) with Special Emphasis on Streptomyces mutabilis M3MT483919
Authors: Hamed Moaz M. , Abdrabo Mohamed A.A. , Fahmy Nayer M. , Abdelfattah Lamis S. , Kelany Mahmoud S. , Abd-El latif Hala H. , El ela Gehan M. Abou , Abd-Elnaby Hanan M , Hassan Sahar W.M.
Published: February 2021

Ten sediment samples were gathered from several geographical locations around mangrove habitat, Red Sea coast, Egypt, during summer 2019. Actinobacteria are widespread in most mangrove soil samples. The average actinomycetes counts in sediment samples were ranged from 4 to 15 CFUg-1, also physico-chemical characters for soil samples were determined. Statistical analysis was applied to assess if the geographical location and physico-chemical characters influenced the communities of actinomycetes. A total of 10 actinomycetes were isolated and characterized physiologically and biochemically. The antimicrobial activities of different actinomycetes isolates were assessed. Isolate M3 was chosen as the most promising isolate with broad antagonistic activity against Bacillus subtilis ATCC 6633, Escherichia coli ATCC 19404, Staphylococcus aureus ATCC6538, Pseudomonas aeruginosa ATCC 9027, and Candida albicans ATCC 10231 with inhibition zones ranged from 12.0 ± 0.9 to 20.0 ± 1.9 mm. Genotypic characterization of isolate M3 was made using 16S rDNA sequence analysis and identified as Streptomyces mutabilis M3 with accession number MT483919. This strain exhibited anticancer activity against breast cancer cell line (Mcf7), liver cancer cell line (HepG2) and colon cancer cell line (HCT116) and the IC50 values were 324.77, 333.71 and 354.46, respectively. Streptomyces mutabilis M3 MT483919 had high bio-flocculating activity for seawater treatment, and the recovery of the samples ranged between 71.97 and 76.05%. The crude extract of Streptomyces mutabilis MT483919 M3 was analyzed by Fourier transform infrared spectrum (FT-IR) and Gas chromatography-mass spectrometry (GC-MS).
Structural Analysis of Avian Encephalomyelitis Virus Polyprotein for Development of Multi Epitopes Vaccine Using Immunoinformatics Approach
Authors: Elhassan Fatima Khalid , Almofti Yassir A. , Abd-elrahman Khoubieb Ali , Nouri Mashair AA , Eltilib Elsideeq EM
Published: February 2021

Avian Encephalomyelitis (AE) is the disease caused by avian encephalomyelitis virus (AEV). The disease mainly affects young birds nervous system worldwide causing high morbidity and variable mortality rate in chicks and noticed egg dropping and hatchability in mature hens. Vaccination is the only way to control AEV infection since there is no treatment yet to the avian encephalomyelitis. This study aimed to use immunoinformatics approaches to predict multi epitopes vaccine from the AEV polyprotein that could elicit both B and T cells. The vaccine construct comprises 482 amino acids obtained from epitopes predicted against B and T cells by IEDB server, adjuvant, linkers and 6-His-tag. The chimeric vaccine was potentially antigenic and nonallergic and demonstrated thermostability and hydrophilicity in protparam server. The solubility of the vaccine was measured in comparison to E. coli proteins. The stability was also assessed by disulﬁde bonds engineering to reduce the high mobility regions in the designed vaccine. Furthermore molecular dynamics simulation further strengthen stability of the predicted vaccine. Tertiary structure of the vaccine construct after prediction, refinement was used for molecular docking with chicken alleles BF2*2101 and BF2*0401 and the docking process demonstrated favourable binding energy score of -337.47 kcal/mol and -326.87 kcal/mol, respectively. Molecular cloning demonstrated the potential clonability of the chimeric vaccine in pET28a(+) vector. This could guarantee the efficient translation and expression of the vaccine within suitable expression vector.
ANALYSIS OF INDUCTIVE SENSOR FIXING CLAMP IN RAILWAY APPLICATIONS
Authors: Schürger Barbara , Kicko Michal , Neumann Vojtech , Frankovský Peter
Published: February 2021

This paper provides static, modal and dynamic analysis of the assembly consisting of fixing clamp, inductive sensor, two fixing bolts and frame applied on railway stock. All the necessary tests to perform this analysis are in accordance with the standard EN 61373: 2010 or the Slovak standard STN EN 61373: 2011. In the next part, a simulation of the tests required for the dynamic analysis of the modelled assembly is performed. For each analysis, von Misses stress is evaluated and then compared to the yield strength of used material. Finally, this work provides a proposal for new design solutions of the fixing clamp based on the obtained results. All analyses were performed in ANSYS Workbench programme using finite element method.
Evaluasi perencanaan anggaran dan kompetensi sumber daya manusia terhadap penyerapan anggaran dengan komitmen manajemen sebagai pemoderasi pada satuan kerja kementerian agama Republik Indonesia di Kota Jambi
Authors: Rahmawati Rahmawati , Amir Amri , Junaidi Junaidi
Published: February 2021

This study aims to analyze budget planning and human resource competence on budget absorption, directly or through management commitment, as a moderating variable in the Indonesian Ministry of Religion Work Unit in Jambi City. This study uses a quantitative approach. Data was collected through a survey using a questionnaire. Data were analyzed using multiple regression analysis (multiple regression) and moderated regression analysis (MRA). The results showed that budget planning and human resource competence simultaneously significantly affected Budget Absorption. There is a positive influence of budget planning factors and human resource competence on budget absorption. Management commitment moderates the influence between budget planning and human resource competence on budget absorption
Pengaruh kualitas pelayanan, harga, dan lokasi terhadap kepuasan pelanggan PT.Dwi Karya Sartika
Authors: Krisna Marpaung Fenny , N. Hutagalung Irma , Mariana Tinambunan Maria , Jeremi Siahaan Nico , H. Siregar Lamhoras
Published: February 2021

The purpose of the implementation of this research is to prove and determine the magnitude of the influence of the independent variable of service quality, the independent variable of price, and the independent variable of location on the dependent variable of customer satisfaction at PT.Dwi Karya Sartika Medan. The sampling technique used was random sampling, thus the sample used was to carry out regression testing on 84 research respondents and 30 study respondents to carry out the reliability and validity test. Hypothesis testing is to use multiple linear regression analysis. The results of the research implementation of the independent variable of service quality, the independent variable of price, and the independent variable of location contributed partially to the dependent variable of customer satisfaction PT.Dwi Karya Sartika. The result of the test of the coefficient of determination is 0.758, which means that the resulting or predicted influence of the free variable of service quality (X1), price free variable (X2), and location independent variable (X3) on the dependent variable of customer satisfaction (Y) is 75.8%, while the remaining 24.2% is predicted or influenced by independent variables which are not included in the implementation of this research.
Analisis ekspor kopi Indonesia
Authors: Nopriyandi Rexsi , Haryadi Haryadi
Published: February 2021

This study aims to analyze the factors that influence Indonesian coffee exports. The data in this study is time series data, which were obtained from various government agencies. The Error Correction Model (ECM) method is used to analyze the effect of coffee prices, GDP and the exchange rate on the volume of Indonesian coffee exports. The estimation results find that coffee prices, Indonesian GDP and exchange rates have a short-term relationship and a long-term balance of the volume of coffee exports. Based on the long-term estimation of the coffee price variable, GDP and exchange rates do not significantly affect the volume of coffee exports, while in the short term these three variables influence the volume of coffee exports
Analisis produktivitas tenaga kerja sektor pertanian di Sumatera
Authors: Oktavia Awina , Zulfanetti Zulfanetti , Yulmardi Yulmardi
Published: February 2021

The aims of this study was to analyze the effect of education and the exchange rate of farmers on the level of labor productivity in the agricultural sector in Sumatra. The data used is panel data of provinces in Sumatra during 2010-2014. The analysis used a panel data regression model. The results showed that education had significant positive effect, while the farmer exchange rate had a significant negative effect on the level of agricultural sector labor productivity in Sumatra.
Dampak belanja irigasi dan jaringan terhadap output PDRB sektor pertanian dan pertumbuhan ekonomi Kota Jambi
Authors: Aminah Siti , Parmadi Parmadi
Published: February 2021

This study aims to analyze the development of irrigation and network expenditure and the development of GDP output in the agricultural sector of the city of Jambi during the period 2005-2015 and analyze the effect of irrigation and network spending on GDP Output in the agricultural sector and economic growth in Jambi City. The results of the study showed that during the study period of 2005-2015 with an average growth of 61.98%, the average value of GRDP at the price of Jambi City was 157,601.68 in million rupiahs with an average growth of 13.67% and the lowest growth occurred in 2006 at 6.60%. Based on the regression results, the results show that the first model of irrigation and network expenditure has a positive and significant effect on the GRDP of the agricultural sector while in the second model irrigation and network expenditure has no significant effect on economic growth
Pengaruh ketimpangan pendapatan dan kemiskinan terhadap pertumbuhan ekonomi antar pulau di Indonesia
Authors: Rahmadi Selamet , Parmadi Parmadi
Published: February 2021

This study aims to find out and analyze the effect of income inequality and poverty on economic growth on each island in Indonesia. To answer these objectives, panel data regression (pooled data) is used. The results of the study show: (1). the best regressions on estimation models are based on the Chow and the Hausman test using the Fixed Effect Model estimation model for each island in Indonesia. (2). Income and poverty inequality negatively affected economic growth in all islands in Indonesia during the 2015-2018.
Determinan produksi perkebunan karet di Desa Purwasari Kabupaten Bungo
Authors: Rosmeli Rosmeli , Hastuti Dwi
Published: February 2021

Rubber plantations that used to be the mainstay of the community in Jambi Province are now being replaced by oil palm plantations, the same thing also happened in Purwasari Village, Bungo Regency. This study uses primary with respondents as many as 40 rubber farmers, from the results of the study, obtained the results together - the area of land, number of plants, age of plants, labor and fertilization costs have a significant effect on rubber production, while partially planted area and number of plants has a significant effect on rubber production, while the age of the plant, the number of laborers and the cost of fertilization have no significant effect on rubber production. Seen from the scale of production of rubber farmers in Purwasari Village are on the scale of production decreasing returns to scale.
Faktor-faktor yang mempengaruhi penerimaan retribusi daerah di Kota Jambi
Authors: Romiyati Ica , Yulmardi Yulmardi , Bhakti Adi
Published: February 2021

Penelitian ini bertujuan untuk mengetahui perkembangan jumlah penduduk, pertumbuhan ekonomi, belanja daerah dan retribusi daerah, untuk mengetahui pengaruh jumlah penduduk, pertumbuhan ekonomi dan belanja daerah terhadap retribusi daerah di Kota Jambi periode 2000-2016. Jenis data yang digunakan adalah data sekunder yang diperoleh dari Badan Pusat Statistik (BPS). Dalam penelitian ini digunakan metode analisis deskriptif dan kuantitatif menggunakan regresi berganda metode OLS. Hasil penelitian menunjukkan jumlah penduduk, pertumbuhan ekonomi, belanja daerah dan retribusi daerah mengalami peningkatan dari tahun 2000-2016. Berdasarkan hasil regresi berganda metode OLS menunjukkan jumlah penduduk, pertumbuhan ekonomi dan belanja daerah berpengaruh signifikan terhadap retribusi daerah di Kota Jambi tahun 2000-2016
Pengaruh kapasitas sumber daya manusia, pemanfaatan teknologi, dan komitmen organisasi terhadap kualitas laporan keuangan di pemerintahan Kota Medan
Authors: Br Hombing Ayu Kristina , Pandiangan Reggy Reynatasya , Simangunsong Dona , Malau Yois Nelsari
Published: February 2021

The purpose of this study was to determine and analyze the effect of human resource capacity, technology utilization, and organizational commitment on the quality of financial reports in the city government of Medan. The research method used is a quantitative approach. The method of analysis used in this study is Multiple Linear Regression. The results of the determination coefficient analysis obtained a value of 0.118, which means that the Variable Variable of Quality of Financial Statements which can be explained by Variable Variations in Human Resource Capacity, Utilization of Technology and Organizational Commitment is 8% while the remaining 92% is explained by other independent variables such as Internal Control, Understanding Accounting Standards The research results show that Simultaneously Human Resources, Technology Utilization, and Organizational Commitment do not have a positive and insignificant effect on the Quality of Partial Financial Statements. Human Resources and Organizational Commitment have no negative and insignificant effect on the Quality of Financial Statements. Technology Utilization Variable Partially has a positive and significant effect on the Quality of Financial Statements.
Pengaruh pertumbuhan penduduk, inflasi, investasi, upah minimum dan kesempatan kerja terhadap pengangguran di Kota Jambi
Authors: Chandra Aditya Surya , Yulmardi Yulmardi , Erfit Erfit
Published: February 2021

This study aims to: 1) To analyze the development of population growth, inflation, investment, minimum wages, job opportunities and unemployment in Jambi City during 2001-2017., 2) To determine and analyze the effects of population growth, inflation, investment, minimum wages and job opportunities for unemployment in Jambi City during 2001-2017. Based on the research results, it can be concluded that the structural equation I show that the development of population growth, inflation, investment, minimum wages, and job opportunities has fluctuated every year, as well as the unemployment variable which fluctuates annually. Based on the results of the t-test on multiple linear regression, it can be concluded that only the job opportunity variable affects unemployment because the probability is less than 0.05.
Pengaruh pertumbuhan ekonomi terhadap penyerapan tenaga kerja dan kemiskinan di Kabupaten Sarolangun
Authors: Sokian Muhammad , Amir Amri , Zamzami Zamzami
Published: February 2021

This study aims to analyze the effect of economic growth on employment in Sarolangun Regency, and to analyze the effect of economic growth and employment on poverty levels, poverty depths and poverty severity levels in Sarolangun District. The data used in this empirical study are secondary data from the 2001-2017 time series originating from the Central Statistics Agency (BPS) and the Central Statistics Agency of Sarolangun Regency. The analysis method used in this research is descriptive analysis and path analysis. The results showed that economic growth had no significant effect on the dependent variable of labor. Any increase or decrease in economic growth does not affect the increase or decrease in the number of workers in the Sarolangun Regency. Economic growth has a negative direction and has a significant impact on poverty levels, poverty depth, and poverty severity through the workforce in Sarolangun District