bluuebunny/crossref_metadata_2025 huggingface dataset:
“MELHOR PREVENIR DO QUE REMEDIAR” O CASO DO HOSPITAL PRÓ-VIDA S.A.
Authors: Buzin Mariana Morelli , Bueno Giovana
Published: June 2022

O caso para ensino descreve alguns eventos que ocorreram no Hospital Pró-Vida, que é uma instituição localizada no estado de Santa Catarina que atua no mercado há aproximadamente 20 anos. O hospital disponibiliza, por meio do seu corpo clínico, 22 especialidades para atender seus pacientes, sendo a obstetrícia seu carro chefe. A história gira em torno da reunião entre o administrador e os conselhos administrativo e fiscal do hospital. Eles precisam tomar algumas decisões para alavancar os negócios e uma possível estratégia seria, por meio da Governança Corporativa, fortalecer sua imagem perante a sociedade e atrair mais investidores. Porém, seu Jorge Ramos, administrador, logo percebe que não será tão fácil, devido a inúmeros conflitos internos, dentre eles, os diferentes objetivos entre o corpo clínico e a administração do hospital. Como contornar tais conflitos e implantar uma governança corporativa realmente efetiva?
ANÁLISE MULTIDIMENSIONAL DO VALUATION DA PETROBRAS
Authors: DUARTE DENIZE LEMOS , PENEDO ANTONIO SERGIO TORRES , PEREIRA VINÍCIUS SILVA
Published: June 2022

Objetivo: Este estudo teve como objetivo avaliar se houve impacto em relação os eventos de corrupção e as fraudes no valuation da empresa Petrobras
Relevância: A relevância desse estudo encontra-se em reforçar a importância econômica e financeira no processo de avaliação de empresas, de forma a direcionar as decisões dos stakeholders e dos próprios acionistas num ambiente desfavorável e também motivar novos trabalhos no processo de avaliação de empresas e de gestão baseada no valor. Esta pesquisa pode ser utilizada como um guia compacto para comparação das diversas métricas de valuation na estimação do valor, tendo como base de uma das maiores empresas do segmento de petróleo com eventos de corrupção e fraudes. Esses modelos de avaliação são usados por muitos analistas, empresas de investimento e instituições em um nível altamente detalhado, a fim de determinar o valor mais justo de uma empresa para fins de fusões, cisões e aquisições, dissolução de sociedade, liquidação de empresas, investimentos e avaliação de performance de gestores. Essas demandas implicam em decisões que determinam a continuidade ou a descontinuidade de um investimento ou negócio.
Resultado: Como resultado, verificou-se uma discrepância nos modelos analisados, apesar de alguns modelos seguirem a mesma tendência de queda ou alta. Os métodos de Valor de Mercado e o Patrimonial Contábil foram os que mais se aproximaram, sugerindo que a Petrobras possui baixo Goodwill, e que o preço formado pelo mercado se aproxima do seu valor patrimonial. Cada método possui sua limitação, bem como algumas avaliações possuem certo grau de subjetividade, pois lidam com expectativas, como no caso dos cenários projetados para o modelo de FDC ou CFF, devido incorporar premissas subjetivas e hipóteses. Destaca-se que o valor da empresa Petrobras, nas múltiplas dimensões de valuation, teve um impacto de deterioração em decorrência das fraudes, corrupção e por outros contratempos na gestão do negócio, como baixa eficiência operacional, alta concentração de endividamento e uma sistemática contínua de desinvestimentos, que está alinhada ao planejamento da companhia.
Conclusão: não existe uma métrica de valuation mais correta ou mais assertiva em sua totalidade, mas sim, um parâmetro direcional, no qual deve ser utilizado como base para a tomada de decisão concomitantemente com outros indicadores.
CRIAÇÃO E COMBINAÇÃO DE RECURSOS PARA VANTAGEM COMPETITIVA: EVIDÊNCIAS DAS HAMBURGUERIAS DE BRASÍLIA
Authors: VIEIRA DANIEL PIRES , DA COSTA CAROLINE CORDOVA BICUDO , DE OLIVEIRA TAUÁ QUEIROZ GRISOLIA
Published: June 2022

Objetivo: analisar características de recursos disponíveis em hamburguerias de marca própria.
Design/metodologia/abordagem: procedeu-se com a abordagem qualitativa, em um estudo exploratório e descritivo de múltiplos casos. Foram realizadas entrevistas semiestruturadas a proprietários de cinco hamburguerias de Brasília. Os dados foram analisados por meio de análise de conteúdo categorial.
Resultados: apenas um conjunto restrito de recursos foi capaz de proporcionar a situação de vantagem competitiva, reforçando a ideia de heterogeneidade de recursos. Destaca-se que empresas com mais tempo de mercado ou com acesso a capital para investimento foram as que mais apresentaram recursos distintivos, reiterando o papel da dependência de trajetória e da capacidade da gestão. Os resultados evidenciaram que mesmo recursos raros, mas não de difícil imitação ou substituição, quando empregados de forma conjunta, são capazes de gerar vantagens competitivas sustentáveis. Também foi possível mapear um conjunto mínimo de recursos que uma empresa deve ter neste mercado para não ficar em uma situação de desvantagem competitiva.
Originalidade/valor: a perspectiva de utilização conjunta de recursos de não difícil imitação ou substituição para o alcance de vantagens competitivas sustentáveis não é descrita nos trabalhos clássicos da Visão Baseada em Recursos, sendo a principal contribuição do presente estudo.
GESTÃO HUMANIZADA EM TEMPOS DE PANDEMIA: IMPACTOS E CONTRIBUIÇÕES PARA O COOPERATIVISMO
Authors: SAUSEN JULIANA DA FONSECA CAPSSA LIMA , BAGGIO DANIEL KNEBEL , BUSSLER NAIRANA RADTKE CANEPPELE
Published: June 2022

Objetivo: Este artigo tem como objetivo evidenciar como a gestão humanizada impacta e contribui para o cooperativismo, em tempos de pandemia.
Metodologia: Como metodologia, utilizou-se pesquisa bibliográfica, documental e entrevistas com gestores e colaboradores de quatro cooperativas do Rio Grande do Sul.
Resultados: Os resultados evidenciaram que as estratégias e práticas cooperativistas implementadas nas cooperativas analisadas, são contempladas por todos os pilares da gestão humanizada, sendo que a tecnologia acaba assumindo papel fundamental nesta inter-relação e neste contexto. O estudo permite concluir que a gestão humanizada se constitui como estratégia valorativa e de sustentabilidade, minimizando as consequências negativas geradas pela pandemia, impactando e contribuindo positivamente para o desenvolvimento das cooperativas analisadas e de seus agentes envolvidos, do mercado do cooperativismo e de toda a sociedade.
Contribuições: Apesar do estudo apresentar limitações quanto ao tamanho da amostra e restringir-se a um segmento institucional e contexto específicos, são destacadas suas contribuições teóricas, práticas e sociais quanto a abordagens relacionadas à Covid-19 e demais pandemias, à gestão humanizada e ao cooperativismo e quanto à forma com que tais abordagens impactam nos atores, processos e dinâmicas de desenvolvimento organizacional e territorial, em tempos de complexidade, mudanças e incertezas. Ressalta-se, também, a relevância do estudo para acadêmicos, docentes e teóricos das áreas da gestão, saúde e desenvolvimento, e para gestores e demais stakeholders envolvidos nas dinâmicas de atuação e desenvolvimento do cooperativismo.
Originalidade: O estudo preenche, ainda, uma lacuna de investigação quanto à demanda de estudos sobre as contribuições da gestão humanizada para o cooperativismo e sobre esta inter-relação no contexto da pandemia.
Nautical Sports Tourism: An exploratory analysis on opportunities for future development
Authors: Cavalheiro Mariana Brandão , Mayer Verônica Feder , Luz Aline Barbosa Tinoco , Queiroz Neto Ambrozio Correa
Published: June 2022

Nautical tourism has become a very popular tourism niche either for practitioners or spectators. Due to the COVID-19 outbreak, new concerns to tourists as well as different motivations to travel have emerged. In this context, the appreciation of simpler lifestyles, contact with nature and water and the practice of outdoors activities are the new trend in the post-COVID-19 world. Therefore, with the purpose to identify managerial, governmental and academic opportunities to develop this promising sector, a literature review on Nautical Sports Tourism was developed. Following a four stages bibliometric analysis (Database selection, search criteria, data selection and analysis of results), this study revealed that, although it regards a topic of considerable growing interest, there is still a long way for the nautical sports tourism literature research to reach its maturity. Regardless of the unquestionable relevance of the current publications, there is still a lack of specific theory development and framework propositions in the field of nautical sports tourism. Even so, it was observed that the combination of sports and tourism in nautical environments opens a myriad of possibilities for places willing to enhance their competitiveness, improve brand image and qualify and diversify the coastal infrastructures.
O turismo cinematográfico no contexto do Programa Filme em Minas A visão dos cineastas acerca da sinergia turismo-cinema
Authors: Gomes Christianne Luce
Published: June 2022

Este artigo se debruça sobre o Programa Filme em Minas, desenvolvido pela atual Secretaria de Estado de Cultura e Turismo de Minas Gerais, e se inscreve no campo denominado de turismo cinematográfico. Algumas perguntas guiaram a pesquisa: os longas-metragens apoiados por essa política pública cultural contribuem para divulgar as localidades mineiras filmadas e promover o turismo neste Estado? A infraestrutura turística local atendeu as demandas das filmagens? A população local dos municípios onde os filmes foram rodados foi beneficiada de alguma maneira? O objetivo deste texto é investigar, junto aos diretores de filmes apoiados pelo Programa Filme em Minas, se essas obras audiovisuais contribuem para potencializar o turismo neste Estado, favorecendo a sinergia turismo-cinema. De abordagem qualitativa, a metodologia envolveu estudo bibliográfico, questionários e entrevistas online com diretores dos filmes selecionados. As respostas foram interpretadas com auxílio da análise de conteúdo. Seja considerando os impactos diretos ou indiretos do turismo cinematográfico, os resultados evidenciaram que a sinergia entre o turismo e o cinema não é simples de ser alcançada. Desse modo, nem sempre o turismo será fomentado simplesmente pelo fato de determinadas localidades aparecerem nas telas do cinema, embora isso seja algo relevante e possa, inquestionavelmente, acontecer. A pesquisa que originou este artigo foi apoiada pelo Conselho Nacional de Desenvolvimento Científico e Tecnológico [310932/2017-3], e pela Fundação de Amparo à Pesquisa do Estado de Minas Gerais/FAPEMIG [PPM-00599-18].
Experiências turísticas na Lagoa Mirim (Brasil/Uruguai): entre práticas e representações
Authors: Kunz Jaciel Gustavo , Castrogiovanni Antônio Carlos
Published: June 2022

A Lagoa Mirim é o maior corpo hídrico do seu gênero no Brasil e no Uruguai, cujo talvegue vem lhe servindo de limite internacional. O objetivo geral foi identificar e analisar práticas turísticas que ocorrem nos sítios estudados, durante o veraneio 2019-2020. O estudo de caso múltiplo compreende documentação, observação direta e entrevistas semipadronizadas, até atingir saturação teórica, seguida de análise qualitativa de conteúdo e triangulação. Os sítios do recorte de estudo são a Praia da Vila da Capilha (Brasil) – localidade histórica no entorno da Estação Ecológica do Taim – o Balneário de Lago Merín (Uruguai) – construído com essa finalidade – e o Porto Pindorama (Brasil) – desativado como terminal. Cada um desses arranjos forja à sua maneira trajetórias de (des)encontro com paisagens e práticas do turismo e/ou lazer. O turismo e o lazer têm-se constituído provisoriamente como um dos usos territoriais nessa área, calcado em paisagens lacustres e práticas sazonais, que envolvem olhar e performar. As práticas observadas e mapeadas são mais vastas que as documentadas e enunciadas. Tais práticas vão além da representação, embora elas não sejam dissociadas no todo da experiência turística lacustre, de que a apreciação das paisagens é parte.
Alocação dos recursos públicos federais em infraestrutura turística realizada pelo Ministério do Turismo - MTur: relações entre os critérios institucionais e a influência política
Authors: Yamamoto Jun Alex , Ardigó Carlos Marcelo , Limberger Pablo Flôres
Published: June 2022

No Brasil, não é incomum observar que os interesses políticos se sobrepõem aos aspectos técnicos e científicos. Esse quadro se avoluma quando se trata da alocação de recursos públicos. O presente artigo analisa se alocação dos recursos públicos em infraestrutura turística, realizada pelo Ministério do Turismo – MTur atende aos critérios institucionais ou é impactada pela influência política. Como base teórica, estudou-se sobre influência política,  governança pública no turismo e a Teoria da Agência. Como objeto de estudo, foram definidos os investimentos realizados no período de 2008 a 2018, nos 65 Destinos Indutores, à época. Os investimentos foram mapeados, categorizados e verificados, para se entender de que forma e como foram alocados. Para se analisar se a alocação dos recursos atendeu aos critérios estabelecidos pela política nacional de turismo, à época a Categorização e o Índice de Competitividade, foi adotada a Modelagem de Equações Estruturais. A partir da construção do diagrama de caminho da relação causal, da verificação da consistência dos dados e dos testes de hipóteses, seus resultados confirmaram que os investimentos em infraestrutura turística realizados pelo MTur ainda são moderados pela influência política, porém adotaram, em parte, os critérios indicados nas diretrizes da política nacional de turismo.
Chocolates Bean to Bar e a COVID-19: uma análise dos impactos da pandemia na gestão de empresas de chocolates artesanais brasileiras
Authors: Andrade-Matos Mariana Bueno de , Monteiro Funo Luciana Rosa , Pimentel Thais Rabelo
Published: June 2022

A pandemia da COVID-19 impactou diversas esferas da sociedade e alterou dinâmicas na gestão das empresas. O presente estudo tem o objetivo de compreender de que modo a pandemia da COVID-19 afetou a gestão das empresas de chocolate artesanal no Brasil, especificamente as empresas de chocolates bean to bar – ou seja, feitos pelos mesmos produtores desde a amêndoa até a barra de chocolate. Para tanto, desenvolveu-se uma revisão de literatura sobre o mercado de chocolates artesanais no Brasil e as dificuldades enfrentadas por empresas a partir da crise mundial causada pela pandemia da COVID19, que baseou a pesquisa qualitativa. Foram feitas, então, entrevistas semiestruturadas com quatorze membros de quatro associações de chocolates artesanais no Brasil. Os dados coletados foram submetidos à técnica de análise de vídeos de Denzin (2004). A partir das análises, observou-se que as empresas foram impactadas de diferentes maneiras a partir das vivências dos proprietários, da localização de suas fábricas, dos recursos disponíveis e das iniciativas tomadas a partir do conhecimento da crise. A mais significativa mudança na gestão foi a necessidade de adaptação às redes sociais digitais, bem como a profissionalização da presença online e de e-commerce para viabilização da continuidade de operação.
To Assess the Awareness and Knowledge about Glaucoma in Patients Attending Ophthalmology OPD of a Tertiary Care Hospital
Authors: Deanne Mendoza  , Nitin Batra  , Arun Bhatti
Published: June 2022

BACKGROUND

Glaucoma is characterized by the progressive and irreversible loss of vision due to damage to the optic nerve. If left untreated it can lead to complete blindness. The management of glaucoma involves controlling the disease process to minimize the damage to the optic nerve, an essential part of which is early diagnosis and early treatment. The symptoms develop so slowly that unless the patient is aware and has knowledge about the disease, its early diagnosis is very difficult. Heightened public awareness about glaucoma may increase the chance of identifying undetected cases early. We wanted to assess the awareness and knowledge about glaucoma in patients coming to ophthalmology OPD of a tertiary care hospital in this study.

METHODS

This was a cross-sectional study conducted for one month among patients aged 18 years and above. A total of 205 patients were randomly selected from the ophthalmology OPD. A questionnaire was given to each patient and the responses were noted. Based on the responses given by the patients for each question, scores were given, and a conclusion was drawn. It was cross analysed with the patient’s demographic data.

RESULTS

Among the subjects, 109 (53.17 %) were males and 96 (46.8 %) were females. Out of 205 subjects, only 144 (70.2 %) subjects had heard of the term glaucoma. There were statistically significant differences between different age groups and their awareness of glaucoma (P < 0.001). Yet only 33.9 % had accurate knowledge of the disease.

CONCLUSIONS

Awareness and knowledge of glaucoma are low. An efficient strategy needs to be designed to increase the awareness and knowledge levels of glaucoma.
To Evaluate Diagnostic Efficacy of Nucleated Red Blood Cells (NRBCs) in Neonatal Sepsis
Authors: Monika Kochhar  , Seema Acharya  , Ragini Singh
Published: June 2022

BACKGROUND

Early diagnosis of sepsis in neonates is cardinal. The isolation of the organism from the body fluids is time-consuming and does not reliably exclude the infection even if it is negative. Nucleated red blood cells (NRBCs) are immature erythrocytes that are elevated in association with foetal distress, hypoxia, and inflammation. The purpose of the study was to evaluate the diagnostic efficacy of nucleated red blood cells (NRBCs) in the detection of neonatal sepsis.

METHODS

This was a prospective study which was conducted in the section of haematology, Department of Pathology of Shri Guru Ram Rai Institute of Health and Medical Sciences, Dehradun, Uttarakhand. A total of 92 term neonates admitted to NICU with clinical features and risk factors of sepsis from October 2020 to March 2021 were included in the study. All study neonates were classified into proven sepsis, probable clinical sepsis and no sepsis groups. The NRBC count and haematological parameters were obtained by a fully automated analyzer SYSMEX XN1000 and corroborated with a peripheral blood smear. The data obtained were analyzed using one-way ANOVA with Fisher’s LSD multiple comparison tests or t-test using GraphPad Prism 7 software. A P-value of 0.001 was taken to be statistically significant.

RESULTS

Among the 92 cases studied, 23 were culture-positive sepsis, 31 were of probable clinical sepsis or were culture-negative and the rest 38 cases had no sepsis. In the present study, the difference in NRBC count between the sepsis and no sepsis group was statistically significant (P-value < 0.001). The sensitivity, specificity, positive predictive value and negative predictive value of NRBC count for sepsis were found to be 77. 78 %, 60.52 %, 73.68 % and 65.71 % respectively. The average NRBC count in the mortality group was higher than in live neonates.

CONCLUSIONS

The NRBC count showed comparable or higher sensitivity than haematological parameters. Higher NRBC counts in the mortality group correlated with adverse neonatal outcomes, hence carrying a prognostic value.
Cardiovascular Mapping in Cirrhosis From the Compensated Stage to Hepatorenal Syndrome: A Magnetic Resonance Study
Authors: Danielsen Karen Vagner , Wiese Signe , Busk Troels , Nabilou Puria , Kronborg Thit Mynster , Petersen Claus Leth , Hove Jens Dahlgaard , Møller Søren , Bendtsen Flemming
Published: June 2022

INTRODUCTION:

Arterial vasodilation and hyperdynamic circulation are considered hallmarks of the pathophysiological mechanisms of decompensation in cirrhosis. However, detailed characterization of peripheral, splanchnic, renal, and cardiac hemodynamic have not previously been published in a spectrum from healthy stage to advanced decompensated liver disease with hepatorenal syndrome-acute kidney injury (HRS-AKI).

METHODS:

We included 87 patients with cirrhosis and 27 healthy controls in this prospective cohort study. The population comprised patients with compensated cirrhosis (n = 27) and decompensated cirrhosis (n = 60); patients with decompensated cirrhosis were further separated into subsets of responsive ascites (33), refractory ascites (n = 16), and HRS-AKI (n = 11). We measured portal pressure and assessed regional blood flow by magnetic resonance imaging.

RESULTS:

Patients with compensated cirrhosis experienced higher azygos venous flow and higher hepatic artery flow fraction of cardiac index than controls (P < 0.01), but other flow parameters were not significantly different. Patients with decompensated cirrhosis experienced significantly higher cardiac index (P < 0.01), higher superior mesenteric artery flow (P = 0.01), and lower systemic vascular resistance (P < 0.001) compared with patients with compensated cirrhosis. Patients with HRS-AKI had the highest cardiac output and lowest renal flow of all groups (P < 0.01 and P = 0.02, respectively). Associations of single hemodynamic parameters were stronger with model for end-stage liver disease than with portal pressure.

DISCUSSION:

The regional cardiocirculatory changes seem closely linked to clinical symptoms with 3 distinguished hemodynamic stages from compensated to decompensated cirrhosis and, finally, to HRS-AKI. The attenuated renal perfusion despite high cardiac output in patients with HRS-AKI challenges the prevailing pathophysiological hypothesis of cardiac dysfunction as a causal factor in HRS-AKI. Finally, magnetic resonance imaging seems an accurate and reliable noninvasive method to assess hemodynamics and has potential as a diagnostic tool in patients with cirrhosis.
Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor in a Heart and Liver Transplant Recipient
Authors: Johnson Brett M. , Iskandar Jean-Pierre , Farha Natalie , Yerian Lisa , Modaresi Esfeh Jamak , Lindenmeyer Christina
Published: June 2022

Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMT) have been described in immunosuppressed states, including in post-transplant patients. Here, we discuss a heart-liver transplant recipient who was found to have multifocal hepatic EBV-SMT. His immunosuppression was initially transitioned from tacrolimus to sirolimus because of the proposed benefits of the mechanistic target of rapamycin inhibitors on EBV-SMT. Unfortunately, he suffered acute rejection of his liver allograft while on sirolimus therapy, which ultimately led to consideration of retransplantation.
Panopticon
Authors: Yates Michael D.
Published: June 2022

Capitalism's two main underpinnings are control and exploitation/expropriation. While there are many sites of control they are all generally supportive of the interests of capital, namely, the endless drive to accumulate wealth. They all help to ensure that we behave so that the system continues to reproduce itself. Since workplaces are the sites where profits are extracted from our labor, it is here that control is most critical.
Toward an Ecosocialist Degrowth
Authors: Pedregal Alejandro , Bordera Juan
Published: June 2022

We are facing today the most pronounced and remarkable of all contradictions: that between what ecosocialist Ian Angus calls "capital's time" and "nature's time." As a result, a series of intertwined ecological and social crises have come together, posing existential threats to life on the planet. Everywhere, life, both human and nonhuman, is threatened, and the dangers of the imposition of capital's time on nature's time accelerate decade by decade at levels scarcely imaginable.
A reexamination and realignment of Peziza sensu lato (Pezizomycetes) species in southern South America
Authors: Pfister Donald H. , Healy Rosanne , Furci Giuliana , Mujic Alija , Nouhra Eduardo , Truong Camille , Caiafa Marcos V. , Smith Matthew E.
Published: June 2022

In this study we review recent collections and historical records of epigeous members of the Pezizales formerly placed in the large, heterogenous genus Peziza from temperate southern South America. Recent analyses using molecular phylogenetic methods allow placement of these species in several previously described genera in recognition of the heterogeneity of Peziza. We include species in nine genera, describe one new species (Peziza gamundiae sp. nov.), and propose one new combination (Phylloscypha nothofageti comb. nov.). We also demonstrate that Pustularia microspora is a synonym of the previously described taxon Peziza pseudosylvestris. Our purpose is to draw attention to these taxa in order to promote their collection and study in a modern framework.
Introduction
Authors: Fiedler Eduard
Published: June 2022

Editorial
A Conference Report: ‘Symposium on Language in West Slavic Bible Versions: Shapes and Shifts’ (2 July 2021, Catholic Theological Faculty, Charles University, Prague)
Authors: Hedánek Jiří
Published: June 2022

A Conference Report
Klaus Hemmerle on the Trinitarian Ontology of the Human Person
Authors: Fiedler Eduard
Published: June 2022

The 20th-century quest for a Trinitarian ontology was associated with a critical reconsideration of the modern philosophy of the subject. However, this reconsideration did not reject the question of subjectivity itself. It rather rejected any narrowed ontological assumptions that would identify the very ground of subjectivity with a univocal eidetic structure of being. In its most advanced forms, the modern and postmodern philosophy of the subject proved to be radically structuralist, relational, or even differentialist. While many attempts at Trinitarian ontology have faced this challenge either by adapting Christian dialogical personalism or reviving older metaphysical traditions and notions, e.g., the analogy, the participation, and the concept of the subsisting person, Klaus Hemmerle emphasised in his Theses Towards a Trinitarian Ontology (1976) above all the ontological primacy of the relational self-giving (Sich-Geben), explicated phenomenologically. Every subsisting being, including the human person, gains its concrete contour only from within this relational process. But does this relational reappearance of the human person mean its self-alienated completion, or rather its complete alienation? How can this relational account of the human person be related to older metaphysical, theological, and personalistic traditions? Does Hemmerle avoid the dangerous dissolution of the human person as a mere processual moment of the whole community and the world?
Il Dio dialogico e la persona umana. La dimensione trinitaria dell’antropologia di Romano Guardini
Authors: Frývaldský Pavel
Published: June 2022

Theological anthropology occupies an important place in the extensive work of Romano Guardini (1885–1968). The thinking of the German thinker can be included in the current of dialogical personalism of the 20th century, which brought many stimuli for deepening the view of human existence. Guardini creatively develops this inspiration and, at the same time, continues the classical theological tradition represented especially by the work of St. Augustine and Bonaventure. The article attempts to show that, in Guardini’s thinking, the relational conception of the human person is closely connected with Trinitarian theology. Only in the light of faith in the Triune God does the dialogical essence of human existence become clearer.
“La persona umana-relazionale”: Possibile dialogo tra la triade di Jacques Lacan e l’ontologia trinitaria
Authors: Danišek Martin
Published: June 2022

The present study deals with the term desire (desiderio, Wunsch) in Jacques Lacan’s psychoanalytic approach and aims to find common intersections with Klaus Hemmerle’s vision of Trinitarian ontology. For modern psychology, desire as a constitutive element of the human person is a criterion that distinguishes the human person from the animal. Extinguishing desire in the human person brings many problems in society. If a person wants to fulfill desire that has a relational character with material things, he or she becomes frustrated. Both Jacques Lacan and Klaus Hemmerle have developed the issue of the desire of the human person in their approaches and thus offer certain solutions to the problem of the extinction of desire in the human person.
‘The Golden Thread of Freedom’: Impulses for Considerations on the Relations between the Trinitarian Ontology and Social Reality in the Work of D. C. Schindler
Authors: Macek Petr
Published: June 2022

The article presents the founding elements of the social and political thought of American philosopher and theologian David C. Schindler. The main aim of the article is to examine possible relations between Schindler’s work and the philosophical concept of ‘Trinitarian ontology’. It focuses on Schindler’s approach towards liberalism and analyses his critique of the modern conception of freedom. It suggests that the main pillars of his idea of the social order might be found in the notion of reality as the symbolical order, the conception of human beings as fundamentally relational, and the renewal of the traditional notion of freedom as rootedness in goodness. It concludes with the suggestion that the proper understanding of social reality requires certain ‘social ontology’, the metaphysical interpretation of social life as a part of a broad cosmological order which symbolically manifest the beauty of the source of being. And it is the social ontology based on the notion of freedom and relationality which analogically reflects the main principles of Trinitarian ontology.
Acute glycogenic hepatopathy in pregnancy: a case report and literature review
Authors: Abuzeid Omar , Heiligenstein Mia , Noureddine Lama , Heiselman Cassandra , Bernasko James
Published: June 2022

Objectives

Acute glycogenic hepatopathy (AGH) is a rare complication of poorly controlled diabetes mellitus. This is the first report in the English literature describing accurate diagnosis and management of AGH during pregnancy.

Case presentation

A 46 year-old gravida 4 para 2 presented at 30 weeks gestation with uncontrolled diabetes, ketoacidosis, and severe hypertension. Euglycemia and normotension were achieved within 24 h of admission but serum transaminase levels which had been normal on admission increased to a very high level over several days, and then resolved spontaneously.

Conclusions

AGH may occur during pregnancy and should be considered in the context of chronic poorly controlled overt diabetes, rapid normalization of maternal blood glucose levels following high dose insulin therapy, and unexplained new-onset serum transaminase levels elevation. Accurate diagnosis is important because the correct treatment is conservative management, not delivery.
Estimators for the value of the optimal dynamic treatment rule with application to criminal justice interventions
Authors: Montoya Lina M. , van der Laan Mark J. , Skeem Jennifer L. , Petersen Maya L.
Published: June 2022

Given an (optimal) dynamic treatment rule, it may be of interest to evaluate that rule – that is, to ask the causal question: what is the expected outcome had every subject received treatment according to that rule? In this paper, we study the performance of estimators that approximate the true value of: (1) an a priori known dynamic treatment rule (2) the true, unknown optimal dynamic treatment rule (ODTR); (3) an estimated ODTR, a so-called “data-adaptive parameter,” whose true value depends on the sample. Using simulations of point-treatment data, we specifically investigate: (1) the impact of increasingly data-adaptive estimation of nuisance parameters and/or of the ODTR on performance; (2) the potential for improved efficiency and bias reduction through the use of semiparametric efficient estimators; and, (3) the importance of sample splitting based on the cross-validated targeted maximum likelihood estimator (CV-TMLE) for accurate inference. In the simulations considered, there was very little cost and many benefits to using CV-TMLE to estimate the value of the true and estimated ODTR; importantly, and in contrast to non cross-validated estimators, the performance of CV-TMLE was maintained even when highly data-adaptive algorithms were used to estimate both nuisance parameters and the ODTR. In addition, we apply these estimators for the value of the rule to the “Interventions” study, an ongoing randomized controlled trial, to identify whether assigning cognitive behavioral therapy (CBT) to criminal justice-involved adults with mental illness using an ODTR significantly reduces the probability of recidivism, compared to assigning CBT in a non-individualized way.
Accuracy assessment of available airborne gravity data in the central western desert of Egypt
Authors: Zaki Ahmed , Younes Ebtehal , El Ghrabawy Osama , Azab Islam Hassan , Rabah Mostafa
Published: June 2022

In the current study, the accuracy of airborne gravity data is evaluated based on the most recent Global Geopotential Models (GGM) and terrestrial gravity data to find out to what extent these data are acceptable to be used in multi-applications (e. g., geodesy and geophysics). To achieve this goal, the remove-compute-restore (RCR) scheme, upward, and downward continuation operational methods (least square collocation and fast Fourier transform procedures) are applied. The airborne gravity data had been acquired by the Egyptian Nuclear Material Authority (ENMA) in the central-western desert for geological applications. Firstly, three GGMs models (EGM2008, EIGEN-6C4 and XGM2019e up to various degrees) are used to compare with the free-air airborne gravity anomaly, The EGM2008 model up to degree 720 produces the smallest mean and STD difference values with 2.59 and 3.07 mGal, respectively. The terrestrial gravity data are compared with the airborne gravity anomaly at both flight and ground levels. In-flight level, the terrestrial gravity data are upward continued to the flight level and compared with the airborne gravity anomaly. The statistical results show that the mean and STD differences are about 4.2 and 0.75 mGal, respectively. While in-ground level evaluation, two operational techniques are used to downward continue the airborne gravity data (Fast Fourier Transform (FFT) and Least Squares Collocation (LSC)). The combined Satellite model EGM2008 up to degree 720 and SRTM 30 m are used to remove and restore the long and short-wavelength information. It is observed that the collocation gives better statistical results than FFT with mean and STD difference values are about 3.13 and 1.13 and mGal, respectively.
Revelation’s Entrenchment in Pure Reason in Fichte’s Versuch einer Kritik aller Offenbarung
Authors: Kravitz Amit
Published: June 2022

According to Kant’s dictum, morality leads inescapably to religion. Notably, this implies two unavoidable shifts: From ‘morality’ to the ‘religion of reason’ and from the ‘religion of reason’ to ‘positive religions’ (‘revelation’). I explain the grounds for each shift, focusing on the different kinds of necessity involved. I then analyze Fichte’s Versuch einer Kritik aller Offenbarung (1792), which mainly addresses the second shift, discussed only briefly by Kant. As I show, whereas for Kant revelation is conditioned by a prior free determination of the will, for Fichte it obtains a primordial status. I explain how Fichte’s approach fills in the Kantian gap between the concept of God, which seems to exclude the possibility of revelation, and the unavoidable human need to assume such an occurrence.
A robust association test with multiple genetic variants and covariates
Authors: Lee Jen-Yu , Shen Pao-Sheng , Cheng Kuang-Fu
Published: June 2022

Due to the advancement of genome sequencing techniques, a great stride has been made in exome sequencing such that the association study between disease and genetic variants has become feasible. Some powerful and well-known association tests have been proposed to test the association between a group of genes and the disease of interest. However, some challenges still remain, in particular, many factors can affect the performance of testing power, e.g., the sample size, the number of causal and non-causal variants, and direction of the effect of causal variants. Recently, a powerful test, called T

REM
, is derived based on a random effects model. T

REM
has the advantages of being less sensitive to the inclusion of non-causal rare variants or low effect common variants or the presence of missing genotypes. However, the testing power of T

REM
can be low when a portion of causal variants has effects in opposite directions. To improve the drawback of T

REM
, we propose a novel test, called T

ROB
, which keeps the advantages of T

REM
and is more robust than T

REM
in terms of having adequate power in the case of variants with opposite directions of effect. Simulation results show that T

ROB
has a stable type I error rate and outperforms T

REM
when the proportion of risk variants decreases to a certain level and its advantage over T

REM
increases as the proportion decreases. Furthermore, T

ROB
outperforms several other competing tests in most scenarios. The proposed methodology is illustrated using the Shanghai Breast Cancer Study.
The Epigenetics of Anxiety Pathophysiology: A DNA Methylation and Histone Modification Focused Review
Authors: Persaud Nikita S. , Cates Hannah M.
Published: June 2022

Anxiety is one of the most common psychiatric disorders diagnosed in the United States today. Like all mental illnesses, anxiety pathology includes genetic, molecular, somatic, and behavioral characteristics. Specific brain regions implicated in anxiety include the prefrontal cortex, amygdala, hippocampus, and hypothalamus. Together, these regions regulate fear-related learning and memory processes, and are innervated by neuronal projections that use glutamate and GABA as neurotransmitters. Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) are also implicated in anxiety. This review discusses the neuroepigenetics of the anxiety phenotype. While studying such changes is limited to postmortem brain studies or peripheral tissue acquisition in humans, the use of animals to model anxiety phenotypes has made epigenetic research possible. In this review, we summarize and discuss a plethora of DNA methylation, histone modification, and associated gene expression differences underscoring the anxiety phenotype. The findings we outline include expression changes of various DNA methyltransferases and changes in histone modifications that affect the hypothalamic pituitary adrenal axis and stress response as well as GABA, glutamate, and BDNF signaling in the PFC, amygdala, hypothalamus, and hippocampus. Furthermore, there have been studies showing that anxiety behaviors and biological scars from stress can be reversed using histone deacetylase inhibitors, and we discuss ideas for the future of treatment. In this review, we hope that by compiling much of the data pertaining to DNA methylation and histone modificationsin vivoanimal studies we are able to highlight potential avenues for future research despite existing limitations.
Women Auteurs, Western Promises
Authors: White Patricia
Published: June 2022

In this essay, Patricia White discusses the ways in which directors Kelly Reichardt, Chloé Zhao, and Jane Campion contend with the legacy of the Hollywood Western in the context of global cinema in their recent films First Cow (2019), Nomadland (2020), and The Power of the Dog (2021) respectively. Representing three different generations of women directors working within the American feature-film space, Campion, Reichardt, and Zhao all reference genre to question the masculinist Western ideology of rugged individualism, even as they use these works to distinguish themselves as individuals within the cinematic marketplace of auteurism.
Experience of mothers after the diagnosis of congenital malformation and the expectations of care
Authors: Zampoli Ana Cláudia Monzon , Caldeira Sebastião , Santos Karine Brito dos , Nihei Oscar Kenji , Silva Rosane Meire Munhak da
Published: June 2022

Objective: to understand the experience of mothers after the diagnosis of congenital malformation and the expectations of care from the health and social network. Methods: qualitative research based on Social Phenomenology, with the participation of six mothers living in border towns, by means of semi-structured interviews. Results: the reports brought information about the diagnosis of congenital malformation, the experience of pregnancy, becoming a mother of a child with malformation and the expectations of health and social care. Conclusion: the social group studied experienced the diagnosis of malformation with suffering, emotional repercussions and changes in their daily lives. Contributions to practice: communication by the health team contributes to understanding and facing the malformation. The importance of the family and social network support was highlighted. It is necessary to develop professional skills related to communication and to make more investments in training and working conditions that allow more time for the care of this public.
Who Teaches in Rural Schools in Underdeveloped Areas? An Investigation Based on a Survey of 5,554 Teachers from 117 Towns in H Province in Wuling Mountains Zone, China
Authors: Zhang Tianjiao , Wang Weiping , Yi Li
Published: June 2022

Teacher shortage is a major hindrance to China’s rural education growth in underdeveloped areas, as well as one of the main causes of educational injustice. We conducted a survey of 5,554 teachers from 117 towns in H province in the Wuling Mountains Zone to investigate the issue of rural school teacher supply. From geographical, emotional, and institutional perspectives, we used a polynomial logit model to examine the validity of the “hometown effects” hypothesis. The findings showed that hometown effects exist in China in all three dimensions. The institutional hometown effects are the most pronounced; when compared to open recruitment, teachers sourced through teacher supply augmentation programs (such as the Secondary Normal Graduates Program, Special Position Program, and Targeted Position Program) are more likely to teach in rural schools, particularly more disadvantaged village primary schools or teaching sites. China’s policy of increasing teacher supply has had a considerable positive influence on rural school staffing. Students from rural areas make better teacher candidates; feelings for hometowns should be encouraged among normal school or university students in pre-service education; and the implementation of teacher support policies should be emphasized to retain rural teachers and improve their teaching quality.
NANOCOMPOSITES BASED ON SINGLECOMPONENT AND MULTICOMPONENT POLYMER MATRICES FOR BIOMEDICAL APPLICATIONS
Authors:   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine, BONDARUK O.M. , KARABANOVA L.V. ,   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine
Published: June 2022

The review is devoted to analysis of the publications in the area of polymers of biomedical applications. Different types of the polymer matrices for drug delivery are analyzed, including polyurethanes, hydroxyacrylates, and multicomponent polymer matrices, which created by method of interpenetrating polymer networks. Particular attention is paid to description of synthesized and investigated nanocomposites based on polyurethane / poly (2-hydroxyethyl methacrylate) polymer matrix and nanooxides modified by biologically active compounds.
STUDYING OF THE NANOSTRUCTURIZED POLY(URETHANE-UREA) – POLY(VINYL CHLORIDE) BLEND MODIFIED BY AEROSILS
Authors:   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine, MALYSHEVA T.L. , TOLSTOV A.L. ,   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine
Published: June 2022

An influence of surface adsorption-active centers of fine amorphous silica on physical hydrogen bonding (H-bonding) network in polyurethaneurea (PUU) and nanostructurized polymer blend (PUU/30PVC) was studied by FTIR spectroscopy. PUU was synthesized by prepolymer approach in N,N-dimethylformamide (DMF) solution using poly(propylene glycol) of Mn = 1000, 2,4-tolylene diisocyanate and 2,4-tolylene diamin as a chain extender at a molar ratio of 1:2:1. The compositions were obtained by solution-casting technique using DMF as a solvent. It was found introducing fine silica with hydroxylated surface into PUU matrix enhances segregation of hard urethane-urea segments in oligoether matrix. The maximum of strengthening of the filled composites was observed when silica A-300 content reaches 2–3 % (by weight). Oppositely, introducing silica AM-300 with silylated (by (CH3)2SiCl2) surface into PUU initiates degrading domain structure of elastomer due to interactions between polar groups of chemisorbed molecules of chlorine-containing modifier and proton-donor groups of rigid segments. Modified surface of silica has minor destabilization effect on H-bonding network in nanostructurized polymer-polymer blend. As a result, for producing filled composites without weakening interface interactions and, respectively, reducing the strength and optimal filler content (silica AM-300 or A-300) should be selected as high as 1 % (by weight).
PYROLYTIC MASS-SPECTROMETRY OF THE OLIGOISOPRENE WITH OF TERMINAL HYDROXYL GROUPS
Authors:   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine, BOIKO V.P. , GRISHCHENKO V.K. ,   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine, DMITRIEVA T.V. ,   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine, BORTNYTSKIY V.I. ,   Institute of macromolecular Chemistry NAS of Ukraine, 48, Kharkivske shose, Kyiv, 02160, Ukraine
Published: June 2022

Pyrolytic mass spectrometry was used to evaluate the effect of terminal hydroxyl groups on the composition of thermal degradation products of oligoisoprene obtained using hydrogen peroxide as an initiator in the isopropyl alcohol solution. To interpret the mass spectra of the oligomer, the mass spectra of some low molecular weight alcohols were used. Oxygen-containing groups were found in the mass spectrum of the oligomer, confirming the presence of two types of hydroxyl groups. Peak m/z = 85 corresponds to the fragment from the terminal unit of isoprene directly connected with the primary hydroxyl group, and peak m/z = 127 does the same unit with the terminal fragment of isopropyl alcohol with the tertiary hydroxyl group. This conclusion is confirmed by the presence of peaks resulting from the transformations of the end groups of atoms in the oligomer, which are modeled by the corresponding low molecular weight alcohols.