bluuebunny/crossref_metadata_2025 huggingface dataset:
Dashboard Visualization of Information for Emergency Medical Services
Authors: Christen Oliver M. , Mösching Yannic , Müller Patrik , Denecke Kerstin , Nüssli Stephan
Published: November 2020

In emergency situations, every minute counts. Therefore, staff of emergency medical services (EMS) require easily accessible sources of information to organize and coordinate their work as quickly as possible. Digital dashboards can visualize various information at a glance and have thus potential to meet this need. We developed in cooperation with the Emmental Hospital a prototype of a dashboard, which aims to improve organizational aspects of the EMS. Method: A literature search was conducted in PubMed, IEEE and ACM. The goal was to identify design principles for dashboards. Additionally, several interviews and meetings were held with the EMS staff of the Emmental Hospital and with those of another hospital. The aim was to identify requirements of the EMS staff towards such an organizational dashboard and to transform them into use cases. Results: Considering the collected requirements and standards of dashboard design, a prototype of a dashboard was developed. It consists of several modules that show relevant information items such as news or traffic information. Due to this modular development, content is easily interchangeable. The most important information for the EMS is shown on the dashboard aiming at saving time for information gathering. Conclusion: A digital dashboard offers many advantages and optimization possibilities compared to an analog whiteboard. For example, such a dashboard can be connected to other systems and data can be automatically included. Although we developed our dashboard in cooperation with the EMS of a specific hospital, it can easily be applied and adjusted to other EMS. As a next step, we will perform usability tests with the prototype and start implementing the dashboard.
SLEEPexpert App – A Mobile Application to Support Insomnia Treatment for Patients with Severe Psychiatric Disorders
Authors: Denecke Kerstin , Schneider Carlotta L. , Hertenstein Elisabeth , Nissen Christoph
Published: November 2020

Cognitive behavior therapy for insomnia (CBT-I) is the first-line treatment for patients with insomnia disorder, including patients with severe mental disorders and comorbid insomnia. However, CBT-I is not sufficiently implemented in acute psychiatry settings. To make this treatment more accessible, we are currently adapting CBT-I to the needs of patients with severe psychiatric disorders in the form of a treatment program entitled SLEEPexpert. A core element of SLEEPexpert is keeping a sleep diary and restricting time in bed to increase sleep pressure. Here, we present a mobile application which supports the implementation of SLEEPexpert. The app is kept very simple, specifically designed for the target user group, and offers four main functionalities: entering information into the sleep diary, calculating the sleep efficiency and adapting the sleep window, delivering information on sleep and sleep disorders and accessing the recorded data in the sleep diary. Currently, we are preparing a usability test for the app aiming at fixing usability issues before running a clinical trial to assess the efficacy of this mHealth intervention.
Measures of Decision Aid Quality Are Preference-Sensitive and Interest-Conflicted – 2: Empirical Measures
Authors: Dowie Jack , Kaltoft Mette Kjer , Rajput Vije Kumar
Published: November 2020

Empirical measures of ‘decision aid quality’, like normative ones, are of a formative construct and therefore embody interest-conflicted preferences in their criteria selection and weighting. The preferences of the International Patient Decision Aid Standards consortium distinguish the quality of the decision-making process and the quality of the choice that is made ‘(i.e., decision quality)’. The Decision Conflict Scale features heavily in their profile measure of the former and Decision Quality Instruments (DQIs), have been developed by members of the consortium to measure the latter. We confirm that both of these, and other components, like the higher-level measures, are preference-sensitive and interest-conflicted. Non-financial interest-conflicted preferences are endemic in healthcare research, policy-making, and practice. That they are inevitable means the main problem lies in the denial of this and attitude to and behaviour towards alternatives, equally interest-conflicted.
From Personalised Predictions to Targeted Advice: Improving Self-Management in Rheumatoid Arthritis
Authors: Fahmi Ali , Soyel Hamit , Marsh William , Curzon Paul , MacBrayne Amy , Humby Frances
Published: November 2020

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, that can lead to joint damage but also affects quality of life (QoL) including aspects such as self-esteem, fatigue, and mood. Current medical management focuses on the fluctuating disease activity to prevent progressive disability, but practical constraints mean periodic clinic appointments give little attention to the patient’s experience of managing the wider consequences of chronic illness. The main aim of this study is to explore how to use patient-derived data both for clinical decision-making and for personalisation, with the first steps towards a platform for tailoring self-management advice to patients’ lifestyle changes. As a result, we proposed a Bayesian network model for personalisation and have obtained promising outcomes.
Chronic Disease Self Management Using a Social Networking PHR/UHR
Authors: Kagan Jeremy S.
Published: November 2020

This viewpoint paper presents a potential solution to the “information islands” that are holding back PHR/UHR from becoming truly effective diagnostic information care management tools for patients especially those who suffer from chronic diseases. The solution involves integrating patient portal with a diagnostic data interface layer to create a single access point for caregivers and patients.
Development and Validation of Standardized Pain Management Documentation
Authors: Liljamo Pia , Kinnunen Ulla-Mari
Published: November 2020

Pain management, assessment and documentation is a crucial part of patient care. However, several studies show flaws in pain management processes. Documentation is not unified or even sufficient. The aim of this study was to describe how patient pain management has been recorded using the nursing diagnoses and nursing interventions of a standardized terminology, the Finnish Care Classification, (FinCC), and how that terminology should be further developed. The research data consisted of the daily nursing documentation notes of patient care episodes (n=806) during inpatient days (n=2564) at several specialty units (n=9). The documentation of pain management was found inadequate and insufficient. The results support the development of a new component, Pain management, and its attendant categories in the new version, FinCC 4.0, to help nurses document pain management in their daily work.
The Effect of Chronic Diseases on the Use of Health Technology and Digital Services in the Elderly Population in Finland
Authors: Mielonen Jukka , Kinnunen Ulla-Mari , Saranto Kaija , Kemppi Anssi , Kuusisto Hanna
Published: November 2020

Digital services are growing in the health-care field. The population in Europe is aging, and digital services are on the rise. There are also plenty of new health-care devices on the market. The aim of this study was to survey how elderly people cope with digital services or devices, especially if they are chronically ill. This quantitative study focuses on the impact of chronic diseases on the use of health technology and digital services. The target group of this study is Finnish people aged 65 or over. Based on the results, a chronic disease or disability is not an obstacle to the use of digital services or health-care technology in the Finnish elderly population. The main obstacles to the use of health technology or digital services are complexity, obscure text, or small font size. According to this study, elderly people seem to trust the device or application. Devices, applications, and online services should be designed so that elderly people’s diseases or ability to function are considered.
Semantic Clustering to Augment Qualitative Content Analysis in Exploring Reasons for Emergency Department Transfer Delays
Authors: Peltonen Laura-Maria , Salanterä Sanna , Moen Hans
Published: November 2020

The aim of the study was to explore emergency department transfer delays and to assess the potential of using a semantic clustering approach to augment the content analysis of transfer delay data. Data were collected over a period of 5 months from two hospitals. A set of (unique) phrases describing reasons for transfer delays (n=333) were clustered using the k-means with 1) cluster centroids initiated in an unsupervised fashion and 2) a semi-supervised version where the cluster centroids were initiated with keywords. The unsupervised algorithm clustered 77 % and the semi-supervised 86 % of the phrases to suitable clusters. We chose the better performing approach to augment our content analysis. Three main categories for transfer delays were found as a result. These included 1) insufficient staffing resources, 2) transportation and bed issues, and 3) patient and care related reasons. The findings inform the audit of organisational processes, accuracy of staffing and workflow to reduce transfer delays. Future research should explore implications of semantic clustering approaches to other narrative data sets in health service research.
New Scopes for Practice – Interdisciplinary Webinars for Emergency Medicine and Biomedical Informatics – Health Informatics
Authors: Saranto Kaija , Chronaki Catherine , Garcia-Castrillo Riesgo Luis , Pape-Haugaard Louise B. , Mantas John
Published: November 2020

This paper presents the early outcomes of the educational cooperation between two European academic associations, namely the European Federation of Medical Informatics (EFMI) and European Society of Emergency Medicine (EUSEM). Two webinars were organized in December 2019 and June 2020 to explore areas where mutual education would be beneficial for interdisciplinary cooperation to advance the digitization of emergency departments for the benefit of patients, health professionals and the health system as a whole. Preliminary findings from the analysis of these two webinars are presented and the steps for further cooperation are outlined.
The Master Study in Telemedicine and E-health at the University of Tromsø, Norway, 2005–2018
Authors: Wynn Rolf , Ellingsen Gunnar
Published: November 2020

In this paper we describe the Master Study in Telemedicine and E-health at the University of Tromsø, Norway. The study enrolled its first students in 2005 and was closed in 2018. We describe and discuss the background of the programme, its development and accomplishments and why it was closed. Hopefully, this narrative will be of use to other programmes focusing on e-health.
The Comparison of Smile Aesthetic of Males and Females Based on Buccal Corridor and Smile Arc
Authors: Hadi Lina , Br Sembiring Puspa Maya , Muttaqin Zulfan
Published: November 2020

In performing the orthodontic treatments, patients aim to improve their smile esthetical features which are influenced by the position, size, shape, and color of teeth. However, in recent decades, several aesthetical features that have been studied are buccal corridor, smile arc, incisor display, and gingival display. In this study, 32 subjects composed of 16 males and 16 females were photographed from the front-site by using a DSLR camera within smiling states. Smile arc and buccal corridor measurements were performed via Corel Draw 12 program. The extra broad and broad characteristics were found in male subjects which were 31.2% and 18.8% respectively, while the female subjects had a higher broad proportion of 43.7% and extra broad for 6.3%. The smile arc features in male subjects were found were straight smile (34.4%) and consonant smile (15.6%), in contrast, the percentage of the female students had a higher consonant smile (31.3%) than straight smile (18.8%). This study confirmed similar findings regarding the domination of the buccal corridor broad in the female population, whereas the extra broad is dominated by males. By contrast, the smile arc consonant is dominated by females, while the straight feature is dominated by males.
Boas práticas da gestão de recursos humanos para melhor produtividade organizacional
Authors: Araújo Gilberto Carlos De
Published: November 2020

Este estudo teve o objetivo de analisar as práticas, costumes e políticas organizacionais que induzem à produtividade. A metodologia utilizada foi a pesquisa exploratória tendo como coleta de dados o levantamento bibliográfico. As conclusões mais relevantes são que a produtividade eficaz é induzida pela motivação, fruto de um clima organizacional no qual os colaboradores são entendidos emocionalmente e pessoalmente, pelos gestores organizacionais e pela administração de recursos humanos.
Institusi Bomoh Dalam Masyarakat Melayu Menurut Perspektif Islam
Authors: ABDULLAH SHUHAIRIMI
Published: November 2020

Malay is typically a Muslim in religion. However, there are still some influences and practices of animism, dynamism, Hinduism and Buddhism that cannot be abolished from their beliefs system. The process of “syncretism” which emerged before and after the presence of Islam has been localized and assimilated into their way of life. This kind of process can clearly be seen in the ritual and traditional practices perform by the Malays who viewed themselves as Muslims. Although these practices are viewed as traditional, the influences, however still has a strong place in the eyes of the Malays. This study aims to explore this interesting issue that has been widely practiced among the Malays and to look at it on the Islamic perspectives.
Labour Force Participation of Women in Malaysia
Authors: ABU BAKAR NOR AZNIN , ABDULLAH NOREHAN
Published: November 2020

This article analyses the women labor force participation in Malaysia. The rapid absorption of women into the labor market has been influenced by several factors. The rapid economic growth was due largely to important growth in the manufacturing and services sectors, where substantial and proportionally larger increase of female workers has been registered. Among all sectors of the economy, the manufacturing sector has recorded the highest growth rate during the last decade. The rising in the female labor force participation may also be attributable to improving economic incentives in employment and policies favoring the employment of women. In addition, the combined effects of the increase in years of schooling, access to family planning services, improved maternal and availability of child care, leading to arise in the average age at marriage, have allowed women to take advantage of the increased employment opportunities.
RESPONSE TO CLIMATE CHANGE IMPACT ON PADDY FARMING: THE SYSTEM OF RICE INTENSIFICATION (SRI)
Authors: Agnese Federica , Othman Zakirah
Published: November 2020

The global climate system began posing risks forhuman and natural systems on all continents and across oceans. It is therefore essential to identify and adopt solutions that sustainably increase rice productionandstrengthen crops’ resilience to climate variabilities. The ecosystem-based crop managementtechnique of the System of Rice Intensification (SRI) is an alternativesolution in environmental development plans.In line with the need of developing climate-smart farming management, this narrativereviewaims toaddress to SRI adoption as atransition to more productive, inclusive and sustainable agriculture that promotes the use of climate-resilient crops. Thereview providedevidence that SRI is beneficial toaddress sustainable agricultural practices and enhance resilience against climate change. In conclusion, SRI-based paddy farming responds to the need fora sound functioning of agriculture management and build climate resilience.
EXAMINING THE STUDENTS’ COGNITIVE, AFFECTIVE AND PSYCHOMOTOR ABILITIES IN THE BAKERY INDUSTRY
Authors: Rachmawati E , Mufidah L , Sulistiyani T , Ab Latif ‪Zahidah
Published: November 2020

Bakery industry has risen with the increasing demand of its products. This study aims to examine the students’ abilities in terms of cognitive, affective and psychomotor in supporting the competency needs in the bakery industry. This research tested the abilitiesrequired by the students during industrial training at the bakery stores. This research was conducted at four different bakeries in the area of Yogyakarta within May to July 2019. A total of 90 students participated in the survey. The findings show that apsychomotor ability is the highest skill needed in the bakery industry with 84%, followed by affective (81%) and cognitive (75.3%). This implies that psychomotor ability is the prominent domain in the bakery industry where it involves physical movement, coordination, and the use of motor-skills. This study helps the educational provider to give the correct knowledge to the students with the precise abilities for their future undertakings.
PERFORMANCE STANDARD OF SPA SERVICES WITH THE JAVANESE MASSAGE METHODIN THE ACADEMY OF SOCIAL PROSPERITY "AKK" OF YOGYAKARTA
Authors: Harwiyati Enny
Published: November 2020

Spa is a beauty treatment that not only refreshes and calms the mind. But it also has several healthbenefits. Thispaper discussed the implementation of Spa services refer to the Operational Service Standards (SOP) which will be the main force. The role of the government through four departments, in collaboration with the Indonesian Spa Association together to form Business Standards, Services, National Work Competency Standards (SKKNI), Curriculum Standardization with the Ministry of Education, and Promotion Cooperation Standards withthe Ministry of Tourism.According to the SKKNI employment in the Spa field refers to knowledge, skills, attitudes. The concept of service at Spa refers to excellent service to foster trust in customers. Excellent service must be supported by quality human resources that are reliable, have a vision that is far ahead and can develop strategies and tips for excellent service that has excellence.The Javanese Massage method applies a combination of several body treatments that originate from cultural and technological traditions, with Javanese sorting methods. It is beneficial for the muscles and can be effective in blood circulation, relieving muscle tension, stimulating the rhythmic nerves to achieve a sedative effect, stimulating and calming. In the Spa treatment, there are various body treatments, namely body scrubs, body massages, body masks and aroma therapy.
KNOWLEDGE TRANSFER IN LEAN MANAGEMENT: EXPERIENCE FROM MALAYSIAN SME
Authors: Mohd Zahari Fadhilah , Nordin Norani , Mohd Asaad Mohd Norhasni , Mohamed Roshidah
Published: November 2020

This study explores how SME develops knowledge transfer in Lean management, particularly lean tacit knowledge. Lean tacit knowledge is very significant in ensuring the success of lean management implementation, yet the SMEs often found difficulties due to limited capital and resources. A single case study of Malaysian SME in the automotive industry was selected for this purpose. Results show that lean training, problem solving using case study, factory visit, sharing of lean database and online learning are the common approaches used by the studied company in developing the lean tacit knowledge. Moreover, the accomplishment of this knowledge transfer in lean management necessitatesstrong commitment from the employees and the top management support. This study incorporates some practical implications forthe organizations that aim to implement lean management effectively.
INFORMATION TECHNOLOGY CAPABILITY AND CORPORATE COMMUNICATION IN SME FOOD INDUSTRIES
Authors: Zulkepli Zuraida Hani , Hasnan Norlena , Mohtar Shahimi
Published: November 2020

During this decade, technology has been recognized as one of the important factors for maintaining competitiveness in a global business environment. Malaysia, as a developing country, is moving towards to become internationally technological based manufacturing sectors using technological capabilities. Since the productivity of the organization is highly dependent on the technology capability, managers need to do their best to communicate effectively with their employees in order to facilitate the sharing information that substantially for contribute to the commercial success. Communication is important in connecting employees and employers, or employees and customers in the process of services in manufacturing. Due to an increase in global competition, rapid technological development and changes in customer demand, this makes the performance of food and beverage firms (F&B) has become increasingly dependent on continuous improvements to introduce new products and processes. Therefore, this study interested to focus on the information technology and corporate communication that has been considered as a pre-quisite to improve productivity in food industries. Even though technology is widely implemented and studied in many industries by researchers, IT capability in manufacturing industry is limited and indicated a major gap in SME’s. Furthermore, IT capability highlights the importance in SME’s. This study is a survey research and quantitative research. There are two methods for collecting data that are through an online survey and the distribution of a questionnaire through several manufacturing firms. Due to the importance of the services in the manufacturing sector, this study to explore the contribution towards the business development in manufacturing industries. Hence, the study also discusses the role of IT capabilities in supporting manufacturing practices, especially in the context of food industries.
THE RELATIONSHIP BETWEEN BUSINESS STRATEGY AND ORGANIZATIONAL CULTURE TO THE PERFORMANCE OF PHARMACEUTICAL RETAILERS IN PENINSULAR MALAYSIA: A PILOT STUDY
Authors: Abdullah Usry , Abdul Kadir Kadzrina
Published: November 2020

The objective of this research is to examine the validity and reliability of the instrument for measuring the business strategy and organizational culture in pharmaceutical retailers in Peninsular Malaysia context. To date, the performance of the organizations had been studied by the researchers. However, there are still a limited number of studies done in the pharmaceutical industry, particularly among small retailers in Peninsular Malaysia. Thus, the study to examine of this area is needed and to examine the validity and reliability of the instrument is considered as the first step to facilitate further studies. The survey method was adopted for this study. A pilot test data from 30 respondents were collected and tested using factor analysis, construct validity, and reliability using SPSSV19. The results show that the instrument has a certain degree of reliability and validity and it is suitable for a study in Malaysia context. Hence, future studies can extend this finding and conduct a full scale study to establish empirical relationship between the study variables.
Resenha do livro Geography of Education
Authors: Gomes Marcus Vinicius
Published: November 2020

Resenha do livro Geography of Education de Colin BrockBROCK, Colin. Geography of Education: space and location in the study of education. London: Bloomsbury Academic, 2016. 194p.
Geografia, política educacional e desigualdade: o caso do Programa de Ensino Integral do Estado de São Paulo (2012-2018)
Authors: Girotto Eduardo Donizeti , De Oliveira João Victor Pavesi , Graton Bruna Bardi
Published: November 2020

Neste artigo, apresentamos os resultados do projeto Atlas da Rede Estadual de Educação de São Paulo, discutindo a importância das análises socioespaciais no planejamento das políticas educacionais. Analisamos aqui o Programa Ensino Integral (PEI) implementado pela Secretaria Estadual de Educação de São Paulo (SEDUC-SP) a partir de 2012. Para tanto, elaboramos mapas correlacionados a diferentes variáveis, demonstrando como tal política pública tem contribuído para ampliar as desigualdades socioespaciais e educacionais, privilegiando unidades escolares localizadas em áreas com as melhores condições estruturais da cidade. Além disso, realizamos entrevistas com ex-alunos e gestores de escolas PEI com o intuito de entender como tais sujeitos compreendem e se apropriam da lógica de funcionamento do Programa, baseado em modelo de gestão focado na responsabilização docente e discente – que culpabilizam os indivíduos que compõem a escola pelo fracasso escolar.
An An Analysis of Crystalline Admixtures in Terms of Their Influence on the Resistance of Cementitious Composites to Aggressive Environments
Authors: Dufka Ámos , Žižková Nikol , Brožovský Jiří
Published: November 2020

This paper describes the influence of crystalline admixtures on the chemical resistance of cement composites exposed to aggressive environments. The effect of the crystalline admixtures was determined by a series of physical-mechanical and innovative physical-chemical methods. Specifically, this concerned the measurement of flexural strength, compressive strength, determination of the dynamic modulus of elasticity by the ultrasonic pulse velocity test, and an analysis of the internal structure by mercury intrusion porosimetry and x-ray computed tomography. Physical-chemical analyses were also performed; namely an x-ray diffraction analysis to determine the mineralogical composition and electron microscopy to examine the microstructure. The use of non-destructive testing methods (ultrasonic pulse velocity test and computed tomography) made it possible to compare the properties of the same specimens for 16 months. The specimens were stored in reference laboratory conditions, a sodium sulphate solution and an ammonium chloride solution. The physical-mechanical tests and physical-chemical analyses clearly showed the benefit that crystalline admixtures have for the resistance of cementitious composites attacked by chemically aggressive solutions without affecting the fresh-mixture rheology or decreasing the strength of the composites.
Analysis of the Venezuelan humanitarian crisis and international response to the regional refugee problems
Authors: Kleszczyńska Iga
Published: November 2020

The aim is to analyze the dimension of the humanitarian crisis of Venezuela, with particular emphasis on the importance of regional migration problems and the involvement of the international community.. The article consists of an introduction that focuses on the background of the current migration crisis with particular emphasis on substantive and methodological assumptions and the theoretical perspective. Then, the article focuses on analyzing two major research areas: a) the main social, economic and political causes of the Venezuelan migration crisis; the effects and causes of the crisis for both the Venezuelan economy and the security of the Latin American; and b) the involvement of the international environment, with particular emphasis on the activities of the European Union, the United Nations, Latin American governments and the United States. Hence, the hypothesis indicates that the problem concerning the migration crisis of Venezuela is both caused and deepens further socio-economic problems of pointed country causing a feedback effect. The article is prepared based on a institutional and legal method (analysis of selected initiatives and the shape of public policies supporting the problem of the refugee crisis of Venezuela); systemic (analysis of the impact of the migration crisis on regional security in Latin America); content analysis (in particular documents and statuses of international organizations and governments); descriptive statistics method (analysis of statistical data related to the scale of the economic crisis of Venezuela and the population affected by the refugee problem).
The EU migration policy securitization process: from a domestic to a foreign dimension
Authors: Caballero Vélez Diego , Krapivnitskaya Ekaterina
Published: November 2020

This research addresses the foreign policy strategies of the EU after the 2015 refugee crisis. It investigates to what extent the EU migration policy is part of the European foreign policy. The paper outlines that collective action failure is not provided at the domestic dimension of migration policy and, that in order to overcome it, it is transferred to the external dimension of the EU. It argues that migration, previously considered being part of the state’s domestic affairs, transformed from the issue of domestic policy to the foreign one. Thus, the authors study the interconnection between migration and security as a key element for understanding this “foreignization” process. The development of close cooperation with third countries in the field of migration regulation has become one of the priorities of the overall migration policy of the European Union. However, the EU has not gained much success and migration crisis even more clearly indicated the need to develop an external dimension to the management of migration processes, but on a more pragmatic approach that would ensure the EU’s security interests. The basis for the external dimension of EU migration policy is relations with third countries and linking development assistance with security and border protection issues. The paper analyses EU parliamentary debates before and after the 2015 refugee crisis, by doing so, the interconnection between migration and security is assessed leading to a further understanding about the EU migration “foreignization process”.
The treatment of irregular migrants during COVID-19: a comparative analysis of Italian and Portuguese responses
Authors: Barillà Salvatore FP , Pellicanò Alberto
Published: November 2020

In Southern European countries, the regularization of irregular migrants has been largely used in the past as ex post control policy measure, blamed by several scholars as an emergency remedy for the lack of systematic working immigration policies (Baldwin-Edwards, 1999; Finotelli & Sciortino, 2009). Nonetheless, COVID-19 pandemic and its impact on the essential agricultural chains and elderly homecare led countries like Portugal and Italy to adopt an unprecedented comprehensive regularization, in terms of numbers of people involved and modalities. Prima facie similar in the approach, the two legislations may entail not only different bureaucratical implications, but also different rational, as different are the political and the socio-economic environments behind. The aim of the article is to compare the two emergency legislations on a synchronic dimension. Through the analysis of primary and secondary sources, the article will compare the different approaches of Italy and Portugal in addressing the policy problem after the start of COVID-19 pandemic. As two Southern EU Member States with different views on immigration policies, Italy and Portugal represent an interesting case study to investigate. The article will benefit from an interdisciplinary approach, addressing the issue combining both legal and political literatures. Ultimately, the article will try to assess if the current measures are in line with the regularization policies that have been adopted in the past decade.
Reference Centre for Identification and Control of Chemicals: Role and Place in the National System of Chemical Safety
Authors: Prodanchuk M.G. , Kravchuk O.P. , Kurdil N.V. , Raks V.A. , Mikhailov V.S. , Aleinov P.V.
Published: November 2020

In 2014 Ukraine accepted the OSCE proposal to develop an Integrated Chemical Safety and Security Program in Ukraine (ICSSP) aiming to develop a collaborative framework between the Ukrainian partners, the OSCE and the international partners for an effective and coordinated actions to ensure chemical safety and security.

The main goal of the ICSSP program is to improve Ukraine’s ability to prevent, prepare for and respond to inappropriate handling of chemicals.Effective chemical safety will help to increase the level of protection of chemical materials, associated facilities and vehicles. ICSSP also had to ensure the implementation of modern solutions and coordinated approaches to strengthen the protection of critical infrastructure in Ukraine.

A comprehensive review, conducted as the first step in the implementation of ICSSP, showed that the program should be aimed at introducing national activities in the field of chemical safety by a wide range of national authorities with a focus on the development of legislative and administrative measures for the implementation of United Nations Security Council Resolution 1540 in the chemical industry.

Realization of the program objectives will provide:

— creating a national (regional) Reference Centre for Identification and Control of Chemicals, able to make expert conclusions regarding hazardous chemicals and precursors quickly and reliably;

— expanding opportunities to detect chemicals, conduct toxicological studies, including for the purpose of export control and forensic investigations, and the possibility to clarify the nature and characteristics of “unknown” chemicals;

— improving capabilities of regional network of chemical analytical laboratories to identify toxic chemicals and ability to conduct joint research, as well as to train laboratory personnel and to exchange good laboratory practices.

The National Reference Centre can serve as a model laboratory and national (regional) training platform for the dissemination of knowledge and best practices.It can help to solve regional problems, because the neighbouring countries Moldova, Georgia, Azerbaijan and even some EU countries also need such assistance.

Key Words: chemical safety, Reference Centre, preventive toxicology.
Two Cases of Recalcitrant Chronic Rhinosinusitis Treated with Endoscopic Maxillary Mega-Antrostomy in Primary Ciliary Dyskinesia
Authors: Noh Haemin , Park Joon Yong , Jung Taesik , Kim Jin Kook
Published: November 2020

Primary ciliary dyskinesia (PCD) results in several characteristic clinical symptoms, including chronic pansinusitis, recurrent infections of the respiratory tract, and infertility. Concerning the rhinologic aspect, medical therapy mainly involving a combination of long-term antimicrobial agents and intranasal steroid sprays can control sinusitis in the majority of cases. But, there are no definite treatment guidelines for recalcitrant chronic sinusitis with PCD. Recently, we examined a 28-year-old male with serous otitis effusion, chronic sinusitis, and bronchiectasis, and a 4-year-old female with chronic sinusitis and serous otitis effusion. We confirmed PCD by electron microscopy and endoscopic maxillary mega-antrostomy was performed in both cases for the treatment of chronic sinusitis that was refractory to conservative management.
Atendimento Odontológico na Zona Rural do Piauí: A extensão colaborando com a experiência acadêmica
Authors: Cardoso Sarah de Araujo Mendes , Sousa Mirna Raquel Rocha de , Uchôa Isabela Soares , Freitas Francisco Ariel Paz Santos , Nascimento Suzanne Tatianne Teixeira , Magalhães Maria do Amparo Velosos
Published: November 2020

A Política Nacional de Saúde Bucal tem o objetivo de aumentar o acesso ao atendimento odontológico em áreas socialmente vulneráveis, porém, fatores estruturais, políticos, econômicos e ambientais interferem na plena atuação do dentista, intensificando as disparidades sociais. No conceito da odontologia preventiva, a promoção de saúde fornece à população ferramentas para melhoria na qualidade de vida, além de fazer do paciente um agente ativo nessa transformação. Nisso, a experiência acadêmica extramuros tem a ferramenta de aproximar o aluno das realidades sociais que o cercam, pois possui uma metodologia ativa no ensino em saúde que gera benefícios para a comunidade que vai interagir com a equipe acadêmica, e para o futuro profissional que saberá conciliar teorias e técnicas científicas com diferentes estruturas socioambientais. Dessa forma, o objetivo desse artigo é relatar a experiência acadêmica de alunos de odontologia que atuaram em zona rural do Piauí como extensionistas do projeto PERES. A atuação da equipe de saúde bucal incluiu prevenção, promoção e recuperação de saúde, onde os estudantes vivenciaram desafios diante da realidade comunitária, como alta prevalência de cárie em crianças, doença periodontal em adultos e próteses mal adaptadas em idosos. Assim, através do contato com a comunidade, houve formulação de percepções sociais no atendimento odontológico e o desenvolvimento da saúde integral e humanitária na formação dos futuros cirurgiões-dentistas.
Valorização dos conhecimentos sobre plantas medicinais: uma abordagem para o ensino de ciências
Authors: Barbosa Alice Silva , Maximo Letícia Marinho , Oliveira Thales Alberto Corrêa , Bastos Antônio Pedro Costa , Lucas Flavia Cristina Araújo
Published: November 2020

As análises de metodologias que vinculam informações científicas ao cotidiano dos alunos colaboram com a reflexão e a construção de um diálogo para o melhor entendimento dos conteúdos. Este artigo buscou valorizar os conhecimentos tradicionais sobre plantas medicinais e utilizá-los no ensino de Ciências como proposta de atividade para as aulas de Botânica, no município de Paragominas, Pará, Brasil. Foi empregada pesquisa-ação, além de entrevistas com 34 alunos e a professora. Fatores como a carência de informação relacionada ao tema, falta de estímulo por parte dos alunos e a necessidade de mais apoio para a realização das aulas, foram apontados como dificuldades para o desenvolvimento de novas abordagens. Os alunos foram bastante participativos, porem demonstraram dificuldades com o emprego da nomenclatura científica, o que gerou desinteresse pela aula. Foram desenvolvidas ações que buscaram promover a interdisciplinaridade dos conteúdos (fotossíntese e cadeia alimentar) e a contextualização do tema proposto por meio da confecção de um jardim de plantas medicinais no ambiente escolar. A montagem do jardim cativou a curiosidade dos alunos e dos funcionários da escola que se sentiram participativos com a prática de ensino adotada.
SPECTROSCOPIC PROPERTIES OF SOLIDIFIED MELTS OF THE EuF3-CeF3-NaCl-KCl SYSTEM
Authors: Zinchenko Viktor , Ieriomin Oleg , Antonovich Valerii , Chivireva Nataliia , Stoianova Iryna , Volchak Ganna , Doga Pavlo
Published: November 2020

The nature of the interaction in the EuF3-CeF3 system in the process of high-temperature (1050 °C) oxidation - reduction reaction was established by the methods of IR transmission spectroscopy, diffuse reflection spectroscopy and fluorescence spectroscopy. Here is a significant bathochromic shift to 480-485 nm band of blue luminescence of Eu(II) - containing phases, due to the 5d–4f electronic transitions, as well as the manifestation of orange-red luminescence of Eu(III) - containing phases due to 4f–4f electronic transitions in the range of 590–690 nm. There is a bathochromic shift of the IR bandwidth in the spectrum of the solidified salt melt as a result of dissolution of the fluoride system. Diffuse reflection spectra reveal changes in the composition of the phases that dissolve in the salt melt due to exchange reactions. The wide absorption band in the UV range gives way to a negative absorption band consisting of two peaks due to luminescence. The almost complete disappearance of the band of 4f–4f transitions in Eu(III) in the near-IR range of the spectrum is evidence of its entire reduction in the chloride melt to Eu(II). The character of the luminescence spectra of solidified salt melts also changes in comparison with the initial sample of the EuF3-CeF3 system, namely, the luminescence band of Ce3+ ions disappears, and the luminescence band of Eu2+ ions at 430–440 nm becomes narrow and highly intensive. The luminescence band of Eu3+ ions in the orange-red region of the spectrum disappears completely. Thus, Eu2+ ions become dominant in the formation of the spectral picture of the solidified salt melt, which is evidence of the completion of the redox process in the system.
In search of lost time: attosecond physics, petahertz optoelectronics, and quantum speed limit
Authors: Zheltikov A M
Published: November 2020

Modern optical physics provides means to detect and resolve ultrafast processes on a time scale of tens of attoseconds. The physical interpretation of such measurements, however, remains the focus of heated debate. In its conceptual dimension, this debate reflects fundamental difficulties in defining time in quantum mechanics. En route toward resolving this difficulty, we are led to extend universal uncertainty relations to ultrafast light–matter interactions. Such a generalized uncertainty sets a lower bound on the response time inherent in attosecond electronic dynamics driven by ultrashort laser pulses, dictating a speed limit for next-generation photonic information systems — systems of petahertz optoelectronics.
L’argomentazione riflessiva come strumento a supporto dei processi di valutazione formativa: il ruolo fondamentale del docente
Authors: Cusi Annalisa
Published: November 2020

In questo articolo vengono proposte alcune riflessioni sul ruolo che il docente svolge nell’implementare pratiche mirate a valorizzare i processi di argomentazione riflessiva a supporto della valutazione formativa in Matematica. Mediante l’analisi di alcuni stralci di discussione, tratti da una sperimentazione condotta in una classe seconda di una scuola secondaria di primo grado, si mettono in luce gli interventi chiave che il docente può proporre per stimolare processi di argomentazione riflessiva e attivare specifiche strategie di valutazione formativa.
Development of a Bioprocess for the Production of Cyclic Lipopeptides Pseudofactins With Efficient Purification From Collected Foam
Authors: Biniarz Piotr , Henkel Marius , Hausmann Rudolf , Łukaszewicz Marcin
Published: November 2020

Microbial surfactants (biosurfactants) have gained interest as promising substitutes of synthetic surface-active compounds. However, their production and purification are still challenging, with significant room for efficiency and costs optimization. In this work, we introduce a method for the enhanced production and purification of cyclic lipopeptides pseudofactins (PFs) from Pseudomonas fluorescens BD5 cultures. The method is directly applicable in a technical scale with the possibility of further upscaling. Comparing to the original protocol for production of PFs (cultures in mineral salt medium in shaken flasks followed by solvent-solvent extraction of PFs), our process offers not only ∼24-fold increased productivity, but also easier and more efficient purification. The new process combines high yield of PFs (∼7.2 grams of PFs per 30 L of working volume), with recovery levels of 80–90% and purity of raw PFs up to 60–70%. These were achieved with an innovative, single-step thermal co-precipitation and extraction of PFs directly from collected foam, as a large amount of PF-enriched foam was produced during the bioprocess. Besides we present a protocol for the selective production of PF structural analogs and their separation with high-performance liquid chromatography. Our approach can be potentially utilized in the efficient production and purification of other lipopeptides of Pseudomonas and Bacillus origin.
Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform
Authors: Colón-Rodríguez Alexandra , Uribe-Salazar José M. , Weyenberg KaeChandra B. , Sriram Aditya , Quezada Alejandra , Kaya Gulhan , Jao Emily , Radke Brittany , Lein Pamela J. , Dennis Megan Y.
Published: November 2020

In recent years, zebrafish have become commonly used as a model for studying human traits and disorders. Their small size, high fecundity, and rapid development allow for more high-throughput experiments compared to other vertebrate models. Given that zebrafish share >70% gene homologs with humans and their genomes can be readily edited using highly efficient CRISPR methods, we are now able to rapidly generate mutations impacting practically any gene of interest. Unfortunately, our ability to phenotype mutant larvae has not kept pace. To address this challenge, we have developed a protocol that obtains multiple phenotypic measurements from individual zebrafish larvae in an automated and parallel fashion, including morphological features (i.e., body length, eye area, and head size) and movement/behavior. By assaying wild-type zebrafish in a variety of conditions, we determined optimal parameters that avoid significant developmental defects or physical damage; these include morphological imaging of larvae at two time points [3 days post fertilization (dpf) and 5 dpf] coupled with motion tracking of behavior at 5 dpf. As a proof-of-principle, we tested our approach on two novel CRISPR-generated mutant zebrafish lines carrying predicted null-alleles ofsyngap1bandslc7a5, orthologs to two human genes implicated in autism-spectrum disorder, intellectual disability, and epilepsy. Using our optimized high-throughput phenotyping protocol, we recapitulated previously published results from mouse and zebrafish models of these candidate genes. In summary, we describe a rapid parallel pipeline to characterize morphological and behavioral features of individual larvae in a robust and consistent fashion, thereby improving our ability to better identify genes important in human traits and disorders.
Wheat Germination Is Dependent on Plant Target of Rapamycin Signaling
Authors: Smailov Bauyrzhan , Alybayev Sanzhar , Smekenov Izat , Mursalimov Aibek , Saparbaev Murat , Sarbassov Dos , Bissenbaev Amangeldy
Published: November 2020

Germination is a process of seed sprouting that facilitates embryo growth. The breakdown of reserved starch in the endosperm into simple sugars is essential for seed germination and subsequent seedling growth. At the early stage of germination, gibberellic acid (GA) activates transcription factor GAMYB to promote de novo synthesis of isoforms of α-amylase in the aleurone layer and scutellar epithelium of the embryo. Here, we demonstrate that wheat germination is regulated by plant target of rapamycin (TOR) signaling. TOR is a central component of the essential-nutrient–dependent pathway controlling cell growth in all eukaryotes. It is known that rapamycin, a highly specific allosteric inhibitor of TOR, is effective in yeast and animal cells but ineffective in most of higher plants likely owing to structural differences in ubiquitous rapamycin receptor FKBP12. The action of rapamycin on wheat growth has not been studied. Our data show that rapamycin inhibits germination of wheat seeds and of their isolated embryos in a dose-dependent manner. The involvement of Triticum aestivum TOR (TaTOR) in wheat germination was consistent with the suppression of wheat embryo growth by specific inhibitors of the TOR kinase: pp242 or torin1. Rapamycin or torin1 interfered with GA function in germination because of a potent inhibitory effect on α-amylase and GAMYB gene expression. The TOR inhibitors selectively targeted the GA-dependent gene expression, whereas expression of the abscisic acid-dependent ABI5 gene was not affected by either rapamycin or torin1. To determine whether the TaTOR kinase activation takes place during wheat germination, we examined phosphorylation of a ribosomal protein, T. aestivum S6 kinase 1 (TaS6K1; a substrate of TOR). The phosphorylation of serine 467 (S467) in a hydrophobic motif on TaS6K1 was induced in a process of germination triggered by GA. Moreover, the germination-induced phosphorylation of TaS6K1 on S467 was dependent on TaTOR and was inhibited by rapamycin or torin1. Besides, a gibberellin biosynthesis inhibitor (paclobutrazol; PBZ) blocked not only α-amylase gene expression but also TaS6K1 phosphorylation in wheat embryos. Thus, a hormonal action of GA turns on the synthesis of α-amylase in wheat germination via activation of the TaTOR–S6K1 signaling pathway.