bluuebunny/crossref_metadata_2025 huggingface dataset:
Résolution des défaillances bancaires et protection des droits et libertés fondamentaux
Authors: Moreau Victoria
Published: March 2024

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Pour résoudre de manière efficace les défaillances bancaires, des pouvoirs exorbitants ont été confiés à des autorités administratives spécialisées.Dans l’exercice de leurs missions, ces dernières limitent les droits et libertés des établissements de crédit, ainsi que ceux de leurs clients, déposants et investisseurs. En ce sens, la légalité de ces dispositifs peut interroger. Il en est de même des règles procédurales qui entourent les actions desdites autorités, ainsi que des recours envisageables, dont les effets semblent défavorablement limités.

International audience
Le contrôle de la formation : Bilan et perspectives
Authors: Warfman Daniel
Published: March 2024

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International audience
Les nouvelles prérogatives du majeur protégé soumis à une mesure pénale
Authors: Olivero Elena
Published: March 2024

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le majeur protégé peine à être pris en considération lorsqu’il entre dans les rouages de la justice pénale. Certaines modifications sommaires ont été apportées pour pallier l’absence de reconnaissance de ce statut particulier, notamment grâce aux interventions du droit constitutionnel et subsidiairement à la réforme du 23 mars 2019. Cependant, pour respecter les droits fondamentaux, le droit substantiel et le droit processuel doivent garantir plus justement les droits des majeurs protégés.

International audience
Réforme de la procédure civile et réforme du droit des contrats. À propos de quelques influences réciproques
Authors: Kamgaing Pierre-Claver
Published: March 2024

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À l’aune de la réforme du droit des contrats par l’ordonnance de 2016 et de la réforme de la procédure civile par la loi du 23 mars 2019 et les textes subséquents, la compénétration entre le contrat et la procédure civile se présente sous un nouveau jour. Ces textes rendent bien compte du phénomène de processualisation du droit des contrats et du phénomène de contractualisation de la justice. La présente analyse entend mettre en relief les aspects contractuels de la réforme de la procédure civile ainsi que les aspects processuels de la réforme du droit des contrats.

International audience
L’incestus des virgo vestalis. Inceste et châtiment dans la Rome antique
Authors: Sofiane Bouhdiba
Published: March 2024

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Dans l’antiquité romaine, l’emmurement était la peine réservée aux virgo vestalis, prêtresses accusées d’incestus, c’est-à-dire ayant rompu leur voeu de chasteté (castitas). Dans tel cas, la vestale était condamnée à la peine capitale. Elle était flagellée nue puis emmurée, viva defossa, tandis que son amant était flagellé à mort. Un enfant éventuellement né de cette union sacrilège était alors considéré comme impur, et jeté dans le Tibre. L’histoire même de Rome est d’ailleurs fondée sur ce supplice. En effet, la vestale Rhéa Silvia, ayant eu des rapports sexuels avec le dieu Mars, donne naissance à Romulus et Remus. Elle mourra emmurée, mais ses enfants échapperont au Tibre, créant la légende de la fondation de Rome. L’article examine le châtiment infligé aux vestales condamnées pour incestus. Dans une première partie, je passerai en revue les cas d’incestus signalés dans l’histoire de Rome. Je décrirai ensuite la peine du viva defossa, qui devait s’accomplir dans la discrétion.

International audience
L’inceste consenti en droit pénal. Les leçons du droit allemand
Authors: Queudet Jade , Thedieck Max
Published: March 2024

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Cette contribution s’inscrit dans le cadre de la présentation de la complexité juridique de l’inceste consenti. L’accent est mis principalement sur le droit pénal allemand. Néanmoins, des parallèles avec le droit français seront réalisés. A l’aide de cette participation, il est permis une comparaison entre les droits pénaux français et allemand. Une mise en lumière des mécanismes juridiques quant à une relation entre membres d’une même famille avec consentement est ainsi étudiée, tant dans leurs apports sociétaux que dans leurs contestabilités.Ce travail a été écrit par deux étudiants, l’une française et l’autre allemand. Nous sommes tous deux en master 2 dans le cursus intégré Dijon/Mayence et inscrits aux deux universités de Dijon et de Mayence

International audience
Rapport de synthèse : Les services internes de sécurité
Authors: Latour Xavier
Published: March 2024

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Apparemment simple à aborder, la notion de services internes de sécurité se révèle en réalité d'une grande complexité. Sans être totalement dissociée du droit commun des activités privées de sécurité, elle s'en écarte sur de plusieurs points.

International audience
Que reste-t-il de l’intérêt légitime au changement de nom ? Étude à l’aune de la loi du 2 mars 2022 relative au choix du nom issu de la filiation
Authors: Aldegheri Estelle
Published: March 2024

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National audience

L’objectif de la contribution réside dans une mise en perspective de l’exigence d’un intérêt légitime pour changer de nom à l’aune de la nouvelle rédaction de l’article 61-3-1 du Code civil issue de la loi n° 2022-301 du 2 mars 2022. Alors que la réforme affiche son ambition de réduire les recours au changement de nom par décret permis à l’article 61 du Code civil, elle pourrait avoir un effet pervers : la création d’un contentieux renouvelé fondé sur l’intérêt légitime subjectif à changer de nom.
Implementation of bit serial CORDIC for Robotic Applications
Authors: Chandrika T
Published: March 2024

CORDIC stands for coordinate rotation digital computer. The key concept of CORDIC arithmetic is based on the simple and ancient principles of 2-D geometry. This iterative formulation of a computational algorithm for its implementation is developed for the computation of trigonometric functions and multiplication. Not only a wide variety of applications of CORDIC have been suggested over the time, but also a lot of progress has taken place in the area of algorithm design and development of architectures for high-performance and low-cost solutions . Rotation of vectors through fixed and known angles has wide applications in robotics, digital signal processing, graphics, games, and animation. Therefore, in this paper, we be present Bit Serial Iterative (BSI) CORDIC Implementation for The Calculation of Trigonometric Functions. Synthesis of the proposed CORDIC Circuit was implemented in xilinx and shown that the proposed design offer higher throughput, less latency for fixed angles of rotation.
Hygroscopicity and movement of medium density fibre board
Authors: Mamatha B S
Published: March 2024

Dimensional stability of Medium Density Fiberboard (MDF) is a critical factor in usage of products. Many problems in the use of wood based products are caused by changes in moisture content due to hygroscopic nature of material. Hence a study on hygroscopicity and movement of commercially manufactured medium density fibre board was carried out. The hygroscopic behaviour was determined by measuring the Equilibrium Moisture Content (EMC) at two extreme conditions i.e., 96% to 35% relative humidity and the movement values were measured for 6mm and 17mm thickness samples. From this study it was observed that the Equilibrium moisture content (EMC) for MDF is lower and comparable with reference to hygroscopicity of Group C Indian timbers. The movement values for the medium density fibre boards exposed between 96%RH and 35% RH were found to be 0.28% in width, 4% in thickness
Pengaruh Efikasi Diri dan Prokrastinasi Akademik Siswa Terhadap Pemahaman Konsep Matematika (Survey di SMP Se-Kecamatan Slawi Kabupaten Tegal)
Authors: Kusuma Ningtyas Pramita Resya
Published: March 2024

Penelitian bertujuan untuk menganalisis dan menguji kebenaran hipotesis tentang pengaruh efikasi diri dan prokrastinasi akademik siswa terhadap pemahaman konsep matematika. Hipotesis Penelitian yang diuji meliputi: Terdapat pengaruh langsung yang signifikan efikasi diri terhadap pemahaman konsep matematika, Terdapat pengaruh langsung yang signifikan prokrastinasi akademik siswa terhadap pemahaman konsep matematika, Terdapat pengaruh langsung yang signifikan efikasi diri terhadap prokrastinasi akademik siswa serta Terdapat pengaruh tidak langsung efikasi diri melalui prokrastinasi akademik siswa terhadap pemahaman konsep matematika secara signifikan. Penelitian dilakukan dengan metode survey, dianalisis dengan analisis jalur (path analysis). Hasil pengujian hipotesis diperoleh kesimpulan sebagai berikut. (1) Terdapat pengaruh langsung yang signifikan efikasi diri terhadap pemahaman konsep matematika. (2) Terdapat pengaruh langsung yang signifikan prokrastinasi akademik siswa terhadap pemahaman konsep matematika. (3) Terdapat pengaruh langsung yang signifikan efikasi diri terhadap prokrastinasi akademik siswa. (4) Terdapat pengaruh tidak langsung efikasi diri melalui prokrastinasi akademik siswa terhadap pemahaman konsep matematika secara signifikan. Penelitian ini berimplikasi pada peningkatkan pemahaman konsep matematika dilakukan dengan mengurangi prokrastinasi akademik siswa terlebih dahulu, sehingga efikasi diri akan meningkat dengan lebih mudah dalam memahami pelajaran matematika dengan lebih baik dan lebih cepat.
Self Governance Community: Pendidikan Komunitas dalam Strategi Perjuangan Persatuan Waria Tegal
Authors: Ikhda Nurnoviyati
Published: March 2024

Word of Waria tend to negative conotation in the middle of society. Stereotipe of waria that is about life style which oppose against social norm. During the time, our society majority only seeing waria as abnormal idea. As a result, waria as a group and also individual find difficulties in accessing service of public and social relationship.

Tegal Regency  owning community of Waria which organized, named Persatuan Waria Tegal (PWT). PWT focused activity especially in health service and also the potency had by waria becoming member of PWT. To reach the target, PWT conduct Self Governing Community .

This research aim to to know how PWT conduct Self Governance Community By education in community to build social relationship with society and state.

Result of research of that PWT have conducted Self Governance Community good enoughly. The next step to develop;build existence by constructing social relationship with society and also government of Tegal Regency.
FIQH KONSELING [Pertautan Trilogi antara Iman, Islam dan Ihsan (TI3) dalam Menjawab Kegelisahan Akademik dan Problematika Pendidikan]
Authors: Saeful Bahri
Published: March 2024

Artikel ini akan menjawab pertanyaan penting bagaimana menemukan kembali relegious insight yang telah hilang dalam diri seorang klen (siswa). Mungkin salah satu sebabnya adalah berbagai persoalan akademik dan problem pendidikan yang dialaminya membuat siswa tertekan dan gelisah, sehingga motivasi belajar menjadi lemah dan tidak bisa mencari solusi pemecahannya. Di sinilah tugas suci Bimbingan Konseling Islam (BKI) dipertaruhkan untuk dapat mengubah sikap dan mental klien ke arah yang lebih baik. Akhirnya, penulis menawarkan Fiqh Konseling dalam Trilogi Iman, Islam dan Ihsan, disingkat (TI3) sebagai salah satu alternatif dalam mengatasi persoalan yang dialami klien (siswa). Karakter dari trilogi tersebut mengantarkan seorang klien menjadi pribadi yang totalitas dalam menjalankan ajaran agama, dan pasrah secara penuh kepada Tuhan-Nya serta selalu optimis dalam kegiatan pembelajarannya.
Ilmu Pengetahuan dan Al-Qur’an (Diskursus Realitas Fenomena Alam)
Authors: Miptakhul Ulum
Published: March 2024

Pandangan al-Qur’an tentang ilmu pengetahuan dan teknologi dapat diketahui dengan menganalisis wahyu pertama yang diterima oleh Nabi Muhammad saw, yakni iqra’. Iqra’ terambil dari akar kata yang berarti “menghimpun”, dari menghimpun lahir aneka ragam makna, seperti menyampaikan, menelaah, mendalami, meneliti, mengetahui ciri sesuatu dan membaca baik tertulis maupun tidak. Wahyu pertama al-Qur’an tersebut mengisyratkan bahwa menuntut ilmu adalah suatu perintah yang wajib dilaksanakan oleh manusia, sebagaimana Nabi Muhammad saw yang menuruti perintah Malaikat Jibril tentang peristiwa di gua hira. Ilmu dapat meningkatkan keimanan seseorang, karena selain membuktikan kebenaran al-Qur’an tentang fenomena alamiah yang ilmiah, juga dapat menjadikan karakter seseorang yang berkepribadian mulia, sehingga dapat memperoleh keselamatan baik di dunia maupun di akhirat. Penggunaan ilmu yang tidak berdasarkan al-Qur’an hanyalah akan mendapatkan kehampaan bahkan kesesatan yang berbahaya.
The Effect of the Social Environment on Juvenile Delinquency in Emirati Society: A Field Study
Authors: Alqwatahiay Ali
Published: March 2024

The surrounding social environment in which individuals grow up contributes significantly to the formation of their behavior and relationships with others, so individuals learn different types of behavior through the socialization institutions available in the surrounding social environment. This study examines the impact of the social environment on juvenile delinquency. Using the descriptive approach, questionnaire questions were distributed to a sample of 45 cases. The results showed a strong negative relationship between family upbringing and juvenile delinquency, as the means of individuals’ answers to all items ranged from 3 to 4.30. Family neglect also causes children to resort to bad friends and learn deviance. Additionally, series and films in the media significantly lead to learning about violence and crime.
Clinical challenges and advancements in diagnosing Staphylococcus aureus-associated musculoskeletal infections
Authors: Oh Irvin
Published: March 2024

Musculoskeletal infections (MSKI) present a significant health challenge, with a rising incidence linked to the aging population and advancements in orthopedic surgical care. Staphylococcus aureus is the most prevalent pathogen associated with orthopedic infections. The conventional culture method for identification of pathogen frequently lacks accuracy and is challenged by false-positive or false-negative results. Inflammatory markers such as the erythrocyte sedimentation rate and C-reactive protein are not site-specific or accurate, as they can be confounded by other medical conditions. Identifying the dominant pathogen and monitoring treatment response following surgical debridement and antibiotics therapy continues to pose challenges. Understanding the pathogenesis of MSKI is crucial for the development of innovative diagnostics and alternative therapeutics. S. aureus immune evasion stands out as a key component of the pathogenic mechanism, complicating clinical decisions. Other unique mechanisms such as biofilm and abscess formation, as well as osteocyte-lacuno canalicular network invasion, underscore the need for aggressive debridement and the complete removal of infected implants and bone tissues. Ongoing efforts focus on exploring and developing innovative diagnostics, such as serum immunoassays, next-generation sequencing of infected tissue, transcriptomics of peripheral blood mononuclear cells, and serum proteomics. These endeavors offer promising avenues for improved diagnostics, medical management, and innovative therapeutics for MSKI.
Pandemia e conciliação do trabalho com a vida pessoal e familiar: o caso da Comunidade Intermunicipal do Cávado
Authors: Martins Barroso Margarida , Palma Saleiro Sandra , Franco da Silva Sara
Published: March 2024

Com base nos resultados de um inquérito por questionário aplicado a 2375 trabalhadores/as da administração pública local na Comunidade Intermunicipal do Cávado, este artigo discute os efeitos da pandemia de covid-19 na organização do trabalho e na sua relação com a conciliação do trabalho com a vida pessoal e familiar. A par das mudanças experienciadas por uma parte significativa dos/as trabalhadores/as, os resultados evidenciam também um padrão de permanência tanto nos regimes de trabalho, como na distribuição das responsabilidades familiares, o que permite debater as visões da pandemia como potencialmente transformadora dos modelos habituais de vida e de trabalho.
The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals
Authors: Phillips Jonathan E , Pan Duojia
Published: March 2024

The genomes of close unicellular relatives of animals encode orthologs of many genes that regulate animal development. However, little is known about the function of such genes in unicellular organisms or the evolutionary process by which these genes came to function in multicellular development. The Hippo pathway, which regulates cell proliferation and tissue size in animals, is present in some of the closest unicellular relatives of animals, including the amoeboid organism Capsaspora owczarzaki. We previously showed that the Capsaspora ortholog of the Hippo pathway nuclear effector Yorkie/YAP/TAZ (coYki) regulates actin dynamics and the three-dimensional morphology of Capsaspora cell aggregates, but is dispensable for cell proliferation control (Phillips et al., 2022). However, the function of upstream Hippo pathway components, and whether and how they regulate coYki in Capsaspora, remained unknown. Here, we analyze the function of the upstream Hippo pathway kinases coHpo and coWts in Capsaspora by generating mutant lines for each gene. Loss of either kinase results in increased nuclear localization of coYki, indicating an ancient, premetazoan origin of this Hippo pathway regulatory mechanism. Strikingly, we find that loss of either kinase causes a contractile cell behavior and increased density of cell packing within Capsaspora aggregates. We further show that this increased cell density is not due to differences in proliferation, but rather actomyosin-dependent changes in the multicellular architecture of aggregates. Given its well-established role in cell density-regulated proliferation in animals, the increased density of cell packing in coHpo and coWts mutants suggests a shared and possibly ancient and conserved function of the Hippo pathway in cell density control. Together, these results implicate cytoskeletal regulation but not proliferation as an ancestral function of the Hippo pathway kinase cascade and uncover a novel role for Hippo signaling in regulating cell density in a proliferation-independent manner.
Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes
Authors: Andolina Chiara , Graumans Wouter , Guelbeogo Moussa , van Gemert Geert-Jan , Ramijth Jordache , Harouna Soré , Soumanaba Zongo , Stoter Rianne , Vegte-Bolmer Marga , Pangos Martina , Sinnis Photini , Collins Katharine , Staedke Sarah G , Tiono Alfred B , Drakeley Chris , Lanke Kjerstin , Bousema Teun
Published: March 2024

It is currently unknown whether all Plasmodium falciparum-infected mosquitoes are equally infectious. We assessed sporogonic development using cultured gametocytes in the Netherlands and naturally circulating strains in Burkina Faso. We quantified the number of sporozoites expelled into artificial skin in relation to intact oocysts, ruptured oocysts, and residual salivary gland sporozoites. In laboratory conditions, higher total sporozoite burden was associated with shorter duration of sporogony (p<0.001). Overall, 53% (116/216) of infected Anopheles stephensi mosquitoes expelled sporozoites into artificial skin with a median of 136 expelled sporozoites (interquartile range [IQR], 34–501). There was a strong positive correlation between ruptured oocyst number and salivary gland sporozoite load (ρ = 0.8; p<0.0001) and a weaker positive correlation between salivary gland sporozoite load and number of sporozoites expelled (ρ = 0.35; p=0.0002). In Burkina Faso, Anopheles coluzzii mosquitoes were infected by natural gametocyte carriers. Among salivary gland sporozoite positive mosquitoes, 89% (33/37) expelled sporozoites with a median of 1035 expelled sporozoites (IQR, 171–2969). Again, we observed a strong correlation between ruptured oocyst number and salivary gland sporozoite load (ρ = 0.9; p<0.0001) and a positive correlation between salivary gland sporozoite load and the number of sporozoites expelled (ρ = 0.7; p<0.0001). Several mosquitoes expelled multiple parasite clones during probing. Whilst sporozoite expelling was regularly observed from mosquitoes with low infection burdens, our findings indicate that mosquito infection burden is positively associated with the number of expelled sporozoites. Future work is required to determine the direct implications of these findings for transmission potential.
Structural mechanisms for VMAT2 inhibition by tetrabenazine
Authors: Dalton Michael P , Cheng Mary Hongying , Bahar Ivet , Coleman Jonathan A
Published: March 2024

The vesicular monoamine transporter 2 (VMAT2) is a proton-dependent antiporter responsible for loading monoamine neurotransmitters into synaptic vesicles. Dysregulation of VMAT2 can lead to several neuropsychiatric disorders including Parkinson’s disease and schizophrenia. Furthermore, drugs such as amphetamine and MDMA are known to act on VMAT2, exemplifying its role in the mechanisms of actions for drugs of abuse. Despite VMAT2’s importance, there remains a critical lack of mechanistic understanding, largely driven by a lack of structural information. Here, we report a 3.1 Å resolution cryo-electron microscopy (cryo-EM) structure of VMAT2 complexed with tetrabenazine (TBZ), a non-competitive inhibitor used in the treatment of Huntington’s chorea. We find TBZ interacts with residues in a central binding site, locking VMAT2 in an occluded conformation and providing a mechanistic basis for non-competitive inhibition. We further identify residues critical for cytosolic and lumenal gating, including a cluster of hydrophobic residues which are involved in a lumenal gating strategy. Our structure also highlights three distinct polar networks that may determine VMAT2 conformational dynamics and play a role in proton transduction. The structure elucidates mechanisms of VMAT2 inhibition and transport, providing insights into VMAT2 architecture, function, and the design of small-molecule therapeutics.
Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane
Authors: Morel Camille , Lemerle Eline , Tsai Feng-Ching , Obadia Thomas , Srivastava Nishit , Marechal Maud , Salles Audrey , Albert Marvin , Stefani Caroline , Benito Yvonne , Vandenesch François , Lamaze Christophe , Vassilopoulos Stéphane , Piel Matthieu , Bassereau Patricia , Gonzalez-Rodriguez David , Leduc Cecile , Lemichez Emmanuel
Published: March 2024

Large transcellular pores elicited by bacterial mono-ADP-ribosyltransferase (mART) exotoxins inhibiting the small RhoA GTPase compromise the endothelial barrier. Recent advances in biophysical modeling point toward membrane tension and bending rigidity as the minimal set of mechanical parameters determining the nucleation and maximal size of transendothelial cell macroaperture (TEM) tunnels induced by bacterial RhoA-targeting mART exotoxins. We report that cellular depletion of caveolin-1, the membrane-embedded building block of caveolae, and depletion of cavin-1, the master regulator of caveolae invaginations, increase the number of TEMs per cell. The enhanced occurrence of TEM nucleation events correlates with a reduction in cell height due to the increase in cell spreading and decrease in cell volume, which, together with the disruption of RhoA-driven F-actin meshwork, favor membrane apposition for TEM nucleation. Strikingly, caveolin-1 specifically controls the opening speed of TEMs, leading to their dramatic 5.4-fold larger widening. Consistent with the increase in TEM density and width in siCAV1 cells, we record a higher lethality in CAV1 KO mice subjected to a catalytically active mART exotoxin targeting RhoA during staphylococcal bloodstream infection. Combined theoretical modeling with independent biophysical measurements of plasma membrane bending rigidity points toward a specific contribution of caveolin-1 to membrane stiffening in addition to the role of cavin-1/caveolin-1-dependent caveolae in the control of membrane tension homeostasis.
Proposed Integration of Career Orientation as a Separate Subject in Secondary Curriculum
Authors: Vicente T. Baylon III
Published: March 2024

Proposed Integration of Career Orientation as a separate subject in the Secondary Education Curriculum, this study assesses the perception of a Regular College Students, Transferees, Shifters, Second Coursers-Doctor of Medicine undergoing Bachelor of Science in Nursing in a selected nursing school herein Metro Manila. Secondary Education Curriculum is a list of subjects that must be taken by the high school students per academic year. This task is focus on the assessment of nursing students in terms of age, gender, civil status, and their perception on Career Orientation as a separate subject in Secondary Curriculum.
Aims: The study aimed to assess the knowledge and awareness of college students on the importance of Career Orientation as a separate subject in the secondary education curriculum to develop an essential recommendation to school administrations, Division Office, and Department of Education.
Scope and Limitation of the Study: The central interview was made to the 48 undergraduate students in DCSLC, 27 undergraduate students in OLFU, and 25 Medical Doctors taking up nursing in a selected nursing school herein the Metro Manila.
Research Design: The study employed Descriptive research with the used sample survey method and questionnaire to assess the knowledge and awareness of first courser and second courser college students. A Total of 100 college students from selected nursing school were recruited for this study.
Results: A Total of 100 questionnaires were distributed, collected, validated, and analyzed.
Pear Production (Pyrus communis L.) in Jerusalem, Palestine
Authors: Ighbareyeh Jehad M. H.
Published: March 2024

Pear is a tree belonging to the Rosaceae family, sensitive to different environmental conditions. It is spread in East and West Asia, America and the European Union, and its production has an economic role for many countries of the world, including Palestine. Average annual temperatures and precipitation were analyzed using data from the Palestinian Meteorological Station affiliated with the city of Jerusalem, which was recorded between the years (1993-2014), and equal to the number of years of pear production, noting that the data for pear production was taken from the Palestinian Central Bureau of Statistics. On the other hand, we used Professor Salvador Ravers Martins' methodology to classify the Earth in the process of analyzing environmental factors, there are two aspects of the factors: The first is climatic, which is the amount of rain or precipitation, mean monthly temperature and soil water reserve, and the second factor is the bioclimatic, which is annual ombrothermic index, simple continentality index, compensated thermicity index, and water deficit.
Moreover, we used Professor Salvador Rivers Martinez's methodology for classifying the land in the process of analyzing dependent and independents factors (environmental factors). There are two aspects to the factors: First is climatic, precipitation, mean monthly temperature and soil water reserve, and the second factor (bioclimatic factor), as simple continentality thermicity index, annual ombrothermic index, water deficit and compensated thermicity index.
The Impact of Employee Proficiency on Tanzanian Procurement Contract Management; Evidence from Higher Learning Institutions
Authors: Obadia Shikunzi , Chole Germanus
Published: March 2024

The impact of employee proficiency on Tanzanian procurement contract management; Evidence from higher learning institutions. Interviews, documentary reviews and questionnaires were used as the methods of data collection. The Statistical Package for Social Sciences (SPSS) computer software version 22 was used specifically for the purpose of analyzing the quantitative, while qualitative data were analyzed through content analysis. The findings revealed that an employee should be committed and well-skilled and also that an employer should train their staff on different issues related to procurement contracts management, assigning these tasks to the employees who are experienced enough, as all this leads to effective procurement contracts management. Staff competency has a significant positive influence on performance in procurement contracts management. The more the staff become competent in managing procurement contracts, the more the performance is improved. This indicated that staff are the key factors that will enable the organization to achieve its procurement contractual goals. It was discovered that many staff attended various training and seminars offered by regulators like Public Procurement Regulatory Authority (PPRA) and other professional bodies like the Procurement Supplies Professional and technician Board (PSPTB), therefore it was their fault that affected the effective management of procurement contract in Tanzania higher learning institutions. The study recommended that there must be regular training on procurement contract management for the public staff. The public sector should ensure that their employees are well-trained and educated on procurement contract management issues as it will enable the organization to have employees who will formulate and execute procurement contracts effectively and enable the organization to improve its procurement performance. Higher learning institutions should ensure their procurement officers receive procurement training frequently as needs arise due to frequent changes in procurement policies, procedures or laws. Higher learning institutions should train their employees to increase their skills in the interpretation of the contract. It is considered that well-experienced personnel in contract management are likely to perform great and enable the organization to perform well in contracts.
Pendampingan Pembentukan Paguyuban Pedagang Pasar Plono di Kalurahan Pagerharjo Kapanewon Samigaluh Kabupaten Kulon Progo Daerah Istimewa Yogyakarta
Authors: Dorojati Rini , Triwidaryanta Jaka
Published: March 2024

Dalam kehidupan masyarakat sehari-hari, pasar bukan hanya tempat bertemunya antara penjual dan pembeli tetapi juga sebagai wadah untuk berinteraksi, tempat untuk saling menukar informasi dan mempunyai peran dalam menggerakkan roda perekonomian. Walaupun memiliki potensi ekonomi yang tinggi bagi pengembangan desa, namun masih terdapat kendala dalam aktivitas perdagangannya. Sebagai unit usaha bumdes setempat, pedagang Pasar Plono belum merasakan kesejahteraannya, karena adanya beberapa permasalahan yang dihadapi yaitu aktivitas rentenir yang mengganggu perekonomian pedagang, pelembagaan pedagang sebagai penyalur aspirasi belum terbentuk, konsumen menurun, daya saing dengan pelaku sejenis rendah, budaya kebersihan lingkungan usaha dan tertib parkir lemah. Mengacu permasalahan tersebut, maka pengabdi berusaha untuk turut memecahkan permasalahan dengan memberikan sumbangan bagi solusi berupa pembentukan paguyuban pedagang Pasar Plono. Untuk mewujudkan organisasi pedagang berupa paguyuban terkendala keterbatasan sumber daya pedagang tentang pemahaman sebuah organisasi. maka ditempuh dengan kerjasama antara tim pengabdi bersama pedagang dan BUM Desa Binangun Pagerharjo melakukan sosialisasi, pemetaan masalah dan kebutuhan pedagang dalam berorganisasi, pendampingan studi banding dan fasilitasi pembentukan kepengurusan paguyuban pedagang pasar. Hasil pengabdian, pedagang memiliki kesadaran akan potensi dan permasalahan yang harus dihadapi dalam menjalankan aktivitas ekonomi di Pasar Plono. Pilihan organisasi berupa paguyuban pedagang pasar menjadi solusi mengatasi permasalahan pedagang semakin mantap setelah melakukan studi banding di Paguyuban Pedagang Pasar Kasihan Ngentakrejo. Terbentuknya paguyuban pedagang bermanfaat untuk kelanjutan dan pengembangan usaha, meningkatkan daya saing serta kepercayaan masyarakat, sehingga mampu menjadi pengungkit ekonomi masyarakat desa dan kesejahteraan pedagang.
Methylthioadenosine phosphorylase (MTAP) in hearing: Gene disruption by chromosomal rearrangement in a hearing impaired individual and model organism analysis
Authors: Williamson Robin E. , Darrow Keith N. , Michaud Sebastien , Jacobs Julie S. , Jones Marilyn C. , Eberl Daniel F. , Maas Richard L. , Liberman M. Charles , Morton Cynthia C.
Published: May 2007

Genes with a role in the auditory system have been mapped by genetic linkage analysis of families with heritable deafness and then cloned through positional candidate gene approaches. Another positional method for gene discovery is to ascertain deaf individuals with balanced chromosomal translocations and identify disrupted or disregulated genes at the site(s) of rearrangement. We report herein the use of fluorescence in situ hybridization (FISH) to map the breakpoint regions on each derivative chromosome of a de novo apparently balanced translocation, t(8;9)(q12.1;p21.3)dn, in a deaf individual. Chromosomal breakpoints were assigned initially by GTG‐banding of metaphase chromosomes and then BAC probes chosen to map precisely the breakpoints by FISH experiments. To facilitate cloning of the breakpoint sequences, further refinement of the breakpoints was performed by FISH experiments using PCR products and by Southern blot analysis. The chromosome 9 breakpoint disrupts methylthioadenosine phosphorylase (MTAP); no known or predicted genes are present at the chromosome 8 breakpoint. Disruption of MTAP is hypothesized to lead to deafness due to the role of MTAP in metabolizing an inhibitor of polyamine synthesis. Drosophila deficient for the MTAP ortholog, CG4802, were created and their hearing assessed; no hearing loss phenotype was observed. A knockout mouse model for MTAP deficiency was also created and no significant hearing loss was detected in heterozygotes for Mtap. Homozygous Mtap‐deficient mice were embryonic lethal. © 2007 Wiley‐Liss, Inc.
Die elektrische Leitfähigkeit in der freien Atmosphäre, nach Messungen bei Hochfahrten im Freiballon
Authors: Wigand Albert
Published: May 2007

1. Arbeitsplan. – 2. Meßverfahren. – 3. Ergebnisse der Messungen. – 4. Diskussion der Ergebnisse; a) allgemeiner vertikaler Verlauf der Leitfähigkeit, b) Unipolarität, c) Schwankungen. – 5. Zusammenfassung
Ein Verfahren, um graphisch gewonnene Schallaufnahmen auf dem üblichen glyphischen Wege (Sprechmaschine) wieder hörbar zu machen (Paka‐Verfahren)
Authors: Panconcelli‐Calzia G.
Published: May 2007

Schallaufnahmen auf Wachsplatten mit Berliner‐Schrift werden mit einer besonderen Schalldose gemacht. Diese besteht aus einem Gehäuse aus Metall, aus einer Glasmembran und aus einem steifen Schreibstift, der an dem Gehäuse und an der Membran so angebracht ist, daß er wagerecht zur Wachsplatte schreibt. Dieser Stift endigt in einem möglichst scharf gespitzten Saphir. Die Schalldose kann bei der Aufnahme entweder stehen oder liegen. Mit Hilfe eines Schalltrichters werden die Schallwellen gegen die Membran geführt, die dadurch in Schwingungen versetzt wird. Die Schwingungen werden von dem Stift in das Wachs hineingeritzt. Dieses Verfahren, Schallschwingungen aufzuschreiben, nennt man glyphisch. Nach der Aufnahme wird die Wachsplatte graphitiert und von ihr auf galvanoplastischem Wege eine Matrize gewonnen, wovon wiederum Abzüge auf einer Hartgußmasse angefertigt werden. Diese Abzüge (vulgo: Sprechmaschinenplatten) können auf jeder käuflichen Maschine mit einer Stahlnadel abgehört werden.

Wir haben in der Experimentalphonetik eine andere Kategorie von Apparaten, wobei man anstatt den Schall in den Stoff, also glyphisch, zu schreiben, ihn nur auf den Stoff fixiert. Die dazu nötige Schreibvorrichtung besteht grundsätzlich betrachtet aus denselben Teilen wie die obige für glyphische Aufnahmen, aber mit dem Unterschiede, daß der Schreibhebel etwas länger und biegsamer ist, in einer feinen Feder, z. B. aus Horn, endigt, und die sich drehende berußte Trommel eines Kymographions berührt. Anstatt eines Hebels kann man sich auch eines Lichtstrahls bedienen. Das Verfahren, den Schall so aufzuschreiben, nennt man, im Gegensatze zu dem glyphischen, graphisch.

Die glyphischen Apparate haben den graphischen gegenüber den Vorzug, daß sie eine akustische Wiederbelebung, also ein Abhören des Aufgenommenen, ermöglichen. Die graphischen Apparate aber haben den glyphischen gegenüber wiederum den großen Vorteil, daß sie nicht allein eine genetische, sondern auch eine gennemische Untersuchung von phonetischen Vorgängen gestatten.

Um die Vorzüge der graphisch tätigen Apparate mit denen der glyphischen zu vereinigen, stellte ich 1920, von September bin Dezember, Versuche an. Ich übereilte mich nicht mit deren Bekanntmachung, weil ich abwarten wollte, ob sie nach längerer Zeit vor meiner eigenen Kritik noch standhalten würden. Da dieses nach zwei Jahren aber der Fall ist, so finde ich keine Bedenken, sie zu veröffentlichen. Hrn. Oberwerkmeister Schneider, der mir bei den Versuchen behilflich war, sei hier mein verbindlichster Dank ausgesprochen.
Über einige Anwendungen von Thermoelementen in der Meßtechnik der chemischen Großindustrie
Authors: Gmelin P.
Published: May 2007

Ein registrierender Heizwertmesser. Ein Registrierapparat mit Alarm zum Nachweis von Sauerstoff in Wasserstoff, in Stickstoff und in Wasserstoff‐Stickstoffgemischen.
Pressure distribution analysis of fiber reinforced plastic components made by rubber pressure moulding technique
Authors: Kar Kamal K. , Sharma S. D. , Kumar P. , Ramkumar J. , Appaji R. K. , Reddy K. R. N.
Published: May 2007

Fiber reinforced plastic component (FRP) having complex shaped geometry is prepared by rubber pressure molding (RPM) technique. The technique is based on the matching die set, where the die is made of hard metal like steel and the punch from flexible rubber like materials. The flexible rubber punch intensifies and uniformly redistributes pressure (both operating pressure and developed hydrostatic pressure due to the flexible rubber punch) over the surface of product. The distribution of pressure was analyzed by ANSYS over a processing pressure of 0.5–50 MPa. The analysis was extended to find out the optimum hardness of rubber mold, where the pressure distribution is uniform. For this, analysis was carried out for NR vulcanizates where the loading of carbon black was varied from 0 to 75 phr with an increment of 15 phr. The strain energy density function of 2‐, 3‐, 5‐ and 9 parameter Mooney‐Rivlin; 1st‐, 2nd‐, and 3rd order Ogden; Neo‐Hookean; 1st‐, 2nd‐, and 3rd order Polynomial; Arruda‐Boyce; 1st‐, 2nd‐, and 3rd order Yeoh; and Gent were used. 45phr carbon black loading NR vulcanizate shows best result. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007
Prevalence and etiology of low bone mineral density in juvenile systemic lupus erythematosus
Authors: Compeyrot‐Lacassagne Sandrine , Tyrrell Pascal N. , Atenafu Eshetu , Doria Andrea S. , Stephens Derek , Gilday David , Silverman Earl D.
Published: May 2007

Objective

Studies of adults with systemic lupus erythematosus (SLE) have frequently demonstrated the presence of decreased bone mineral density (BMD). However, there have been few investigations in pediatric patients to date. This study was undertaken to determine the prevalence of low BMD in patients with juvenile SLE and to identify associated risk factors.

Methods

We studied 64 consecutive patients with juvenile SLE in whom routine dual x‐ray absorptiometry (DXA) scanning was performed. Lumbar spine osteopenia was defined as a BMD Z score of <−1 and ≥−2.5, and osteoporosis as a BMD Z score of <−2.5. Decreased hip BMD was defined as a value of <80%. Data on disease activity, quality of life, disease‐related damage, sex, ethnicity, body mass index, age at diagnosis, age at DXA, medication use and duration, clinical features, and puberty status were collected at the time of DXA.

Results

Lumbar spine osteopenia was seen in 24 patients (37.5%) and osteoporosis in 13 (20.3%). Decreased hip BMD was present in 12 patients (18.8%). By univariate analysis, osteopenia was significantly correlated with age, disease duration, duration of corticosteroid use, cumulative corticosteroid dose, azathioprine use, cyclophosphamide use, lupus nephritis, and damage. Two additional variables, mycophenolate mofetil use and class III–IV nephritis, were associated with osteoporosis. Abnormal hip BMD was associated with disease duration, duration of corticosteroid use, and cumulative corticosteroid dose. By multivariate analysis, only disease duration remained in the model for osteoporosis and abnormal hip BMD, while cumulative corticosteroid dose was the variable associated with osteopenia.

Conclusion

These results indicate that osteopenia and osteoporosis are common in juvenile SLE and are associated more closely with increased disease duration than with cumulative corticosteroid dose.
Whole blood viscosity and arterial thrombotic events in patients with systemic lupus erythematosus
Authors: Booth Stephanie , Chohan Saima , Curran James C. , Karrison Theodore , Schmitz Amanda , Utset Tammy O.
Published: May 2007

Objective

To determine if whole blood viscosity (WBV), a rheologic variable contributing to risk of myocardial infarction and stroke in the general population, is elevated in patients with systemic lupus erythematosus (SLE), particularly SLE patients with a history of thrombotic or atherothrombotic events. Because the high rates of arterial and venous thrombosis in lupus cannot be explained by traditional risk factors, elevated WBV may be an easily measurable nontraditional risk factor to identify SLE patients at high risk for thrombotic events.

Methods

Sixty SLE patients (30 with a history of a thrombotic event) and 20 matched controls were recruited into the study. The thrombosis group was further subdivided into an arterial thrombosis group (n = 17). WBV values were determined at 9 different shear rates (1, 2, 5, 10, 50, 100, 150, 300, and 1,000 seconds−1). WBV was then compared between groups by repeated‐measures analysis of variance.

Results

SLE patients with a history of arterial events had significantly elevated WBV relative to either controls (P = 0.022) or SLE patients without arterial events (P = 0.014). WBV in the total SLE group did not differ from controls. Differences in WBV were most prominent at lower shear rates (1, 2, 5, 10, 50, and 100 seconds−1). Anticoagulation, prednisone dose, and antiphospholipid antibodies did not significantly impact WBV.

Conclusion

Our study demonstrated that WBV is selectively elevated in patients with SLE with a history of arterial events. Although this association is striking, longitudinal studies are needed to assess the positive predictive value of WBV for atherothrombotic events in SLE.
Exploratory data analysis for planar tessellations: Structural analysis and point process methods
Authors: Stoyan D. , Stoyan H.
Published: May 2007

This paper presents methods for the exploratory analysis of particular geometrical data, namely planar tessellations. At first, two non‐stochastic methods are suggested which may help to classify tessellations and to understand their structure. The first one consists of approximating a given tessellation by a Dirichlet tessellation. The other one uses the nodes of a given tessellation and tests the possibility of reconstructing it by a fixed rule of connecting nodes by edges.

Furthermore, in order to obtain information on the spatial behaviour of a tessellation, we suggest the use of the methods of point process statistics. In particular, pair correlation and mark correlation functions describe spatial correlations in tessellations.
Comparison of some techniques of multidimensional scaling in soil fauna ecology
Authors: Al Ayoubi B. , Beninel F. , Le Calve G.
Published: May 2007

The aim of this paper is to propose some alternative solutions to a problem proposed by El‐Shishiny and Ghabbour, where the difficulty lies in vagueness rather than randomness. We first propose a city‐block analysis, undoubtedly better adapted to this type of problem than a Euclidean analysis. In the second part we develop a technique consisting in the decomposition of every distance Dij into two parts: the first, a star distance, considered as a personal effect; the second considered as a structure effect. These techniques are illustrated and compared in a real‐life example.
Ecological site classification: An application of clustering
Authors: Owsinski Jan W. , Zadrozny Sławomir
Published: May 2007

This short paper takes up the problem of El‐Shishiny and Ghabbour1 in order to highlight some of the problems in data analysis oriented at recognition of basic data structures, of hierarchy or partition type, with vagueness in initial data and/or the procedure applied. A response to the considered ‘soil fauna taxa versus Sudan sites’ problem is also suggested.
A general model of insurance and investment risk diversification
Authors: Page Dominique , Tremolieres Raymond
Published: May 2007

This article presents a model of insurance and investment risk diversification. An in‐depth analysis of the mathematical formulation of the risk is presented. In this regard, we introduce a new concept called the substitution principle to formulate the model rigorously. We show that, if the investment risks are normally non‐linear, the insurance risks are linear in nature. This proves that the well‐known diversification principle has to be viewed differently in finance and in insurance.
Semantics and factor analysis: An approach to the interpretation of factors
Authors: Lara B. F. , Tartas E. , Oyarzabal P.
Published: May 2007

The interpretation of factors constitutes a major problem in factor analysis. Until now the underlying semantic aspects of the question have been studied only occasionally. However, there are some indications that the mechanical interpretation of the results may constitute in the immediate future a real need in the realm of very large problems. On the other hand, the semantic study of multivariate statistical methods is the only way to warrant the validity of the mechanization procedures and the means to identify their limits.
Estimation of stress‐strength reliability based on tail‐modelling
Authors: Dargahi‐Noubary G. R.
Published: May 2007

In probabilistic design it is common to use parametric statistical models to calculate the probability of failure (Pf) obtained from stress‐strength interference theory. In this respect, it is well known that Pf is sensitive to the shape of the upper and lower tails of the stress and strength distributions respectively and also to their interference. If the true shapes of these tails could be discovered, it would be possible to improve the existing techniques. However, in practice there is seldom sufficient real data available to establish these tails with statistical significance. Moreover, often one or both variables are expensive to sample. Thus a separate tail estimation may not always be possible. Motivated to define a theoretical safety factor, the author presents a method here which provides a general solution to the problem by considering the tail estimation for a sample of increased sized. This is obtained by a reformulation of the problem in terms of excesses over a threshold, and by breaking the analysis into two parts; estimation of the number of exceedances and modelling the excesses. The analysis is carried out by non‐parametric estimation of the former and parametric modelling of the latter based on data from the critical region.