bluuebunny/crossref_metadata_2025 huggingface dataset:
A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes
Authors: Tringides Marios L , Zhang Zhemin , Morgan Christopher E , Su Chih-Chia , Yu Edward W
Published: November 2022

We recently developed a “Build and Retrieve” cryo-electron microscopy (cryo-EM) methodology, which is capable of simultaneously producing near-atomic resolution cryo-EM maps for several individual proteins from a heterogeneous, multiprotein sample. Here we report the use of “Build and Retrieve” to define the composition of a raw human brain microsomal lysate. From this sample, we simultaneously identify and solve cryo-EM structures of five different brain enzymes whose functions affect neurotransmitter recycling, iron metabolism, glycolysis, axonal development, energy homeostasis, and retinoic acid biosynthesis. Interestingly, malfunction of these important proteins has been directly linked to several neurodegenerative disorders, such as Alzheimer’s, Huntington’s, and Parkinson’s diseases. Our work underscores the importance of cryo-EM in facilitating tissue and organ proteomics at the atomic level.
Review of brain–computer interface based on steady‐state visual evoked potential
Authors: Liu Siyu , Zhang Deyu , Liu Ziyu , Liu Mengzhen , Ming Zhiyuan , Liu Tiantian , Suo Dingjie , Funahashi Shintaro , Yan Tianyi
Published: November 2022

The brain–computer interface (BCI) technology has received lots of attention in the field of scientific research because it can help disabled people improve their quality of life. Steady‐state visual evoked potential (SSVEP) is the most researched BCI experimental paradigm, which offers the advantages of high signal‐to‐noise ratio and short training‐time requirement by users. In a complete BCI system, the two most critical components are the experimental paradigm and decoding algorithm. However, a systematic combination of the SSVEP experimental paradigm and decoding algorithms is missing in existing studies. In the present study, the transient visual evoked potential, SSVEP, and various improved SSVEP paradigms are compared and analyzed, and the problems and development bottlenecks in the experimental paradigm are finally pointed out. Subsequently, the canonical correlation analysis and various improved decoding algorithms are introduced, and the opportunities and challenges of the SSVEP decoding algorithm are discussed.
Advances in the understanding and enhancement of the human cognitive functions of learning and memory
Authors: Amoah Daniel Kofi
Published: November 2022

Learning and memory are among the key cognitive functions that drive the human experience. As such, any defective condition associated with these cognitive domains could affect our navigation through everyday life. For years, researchers have been working toward having a clear understanding of how learning and memory work, as well as ways to improve them. Many advances have been made, as well as some challenges that have also been faced in the process. That notwithstanding, there are prospects with regards to the frontier of the enhancement of learning and memory in humans. This review article selectively highlights four broad areas of focus in research into the understanding and enhancement of learning and memory. Brain stimulation, effects of sleep, effects of stress and emotion, and synaptic plasticity are the main focal areas of this review, in terms of some pivotal research works, findings and theories.
Flat Rooftops as Productive Landscapes in Birmingham
Authors: Yang Yangzixian
Published: November 2022

Due to the changing global environment, sustainable development has become a goal that many cities strive towards. Producing nutritious food is a component of sustainable development. The primary purpose of this paper is to assess Birmingham’s suitability for flat rooftop farming. This study explores two examples of rooftop farms: Brooklyn Grange in New York and Thammasat University, the largest rooftop farm in Asia, and they transformed the roof into a productive rooftop farm. This paper proses the tops of the buildings at Birmingham City University to be converted into a flat roof farm with an additional survey into the dietary habits of Birmingham inhabitants. With a productive landscape, one can achieve societal ideals such as urban or communal food self-sufficiency, reduce food imports, transit expenses, and consumer prices, encourage human interaction and connection, and at the same time provide diversified and healthy food.
PENGARUH EKSTRAKURIKULER BOLA BASKET TERHADAP PRESTASI BELAJAR MATA PELAJARAN OLAHRAGA
Authors: Zulfiani Laila Fathia
Published: November 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh kegiatan ekstrakuler bola basket terhadap prestasi belajar mata pelajaran olahraga siswa kelas XI IPA SMAN 10 Semarang. Pokok pembahasan yang dibahas adalah kegiatan ekstrakurikuler yang ada di SMAN 10 Semarang, bagaimana prestasi belajar mata pelajaran siswa XI IPA SMAN 10 Semarang yang mengikuti kegiatan ekstrakurikuler bola basket dan bagaimana pengaruh kegiatan tersebut terhadap prestasi belajar mata pelajaran olahraga siswa XI IPA SMAN 10 Semarang. Populasi penelitian ini adalah seluruh siswa XI IPA SMAN 10 Semarang angkatan 2018/2019. Penentuan sample penelitian menggunakan purposive sampling. Teknik pengumpulan data dalam penelitian ini adalah observasi dan dokumentasi. Berdasarkan uji hipotesis analisis didapatkan nilai Fhitung > Ftabel, atau 8,569 > 0,05. jika nilai Fhitung > Ftabel maka Ho ditolak.  Karena Fhitung lebih besar dibandingkan dengan Ftabel, maka Ho ditolak dan Ha diterima, artinya terdapat pengaruh yang positif dan signifikan antara kegiatan ekstrakurikuler bola basket terhadap prestasi belajar mata pelajaran olahraga siswa kelas XI IPA SMAN 10 Semarang.
MEDIA NUMBER SENSE UNTUK MENGENALKAN BILANGAN PADA ANAK USIA DINI DENGAN MULTISENSORI
Authors: Anwar Ruqoyyah fitri
Published: November 2022

Rendahnya pengenalan konsep bilangan pada anak usia dini disebabkan pengajaran number sense bersifat abstrak dan banyak menggunakan lembar kerja, sehingga dibutuhkan pengembangan media pembelajaran yang dilengkapi panduan bagi guru. Penelitian ini bertujuan untuk mengetahui kelayakan dan keefektifan media pembelajaran Number Sense yang telah dikembangkan dalam meningkatkan kemampuan mengenal bilangan pada anak usia 5-6 tahun di TK Islam Terpadu Al Ibrah Gresik. Metode pengembangan yang dipakai mengikuti model pengembangan Borg and Gall yang mengadaptasi 10 langkah pengembangan model Dick and Carey. Teknik analisis data dengan desain Quasi Eksperimen menggunakan One Group Pretest Posttes Design dengan seluruh sampel yang berjumlah 36 anak. Berdasarkan hasil validasi tiga orang ahli terhadap produk yang dikembangkan, dinyatakan bahwa produk media pembelajaran number sense sudah sesuai dan baik. Hasil penelitian menunjukkan peningkatan rata-rata kemampuan anak sesudah diberi pembelajaran menggunakan media number sense.  Peningkatan ini disebabkan anak tertarik untuk bermain dan senang menggunakan media berupa kartu dan kepingan hitung karena media tersebut bersifat multisensori, yaitu melibatkan modalitas belajar anak baik visual, auditory, kinesthetic, maupun tactile sehingga anak bisa dengan mudah mengenal konsep bilangan dan operasinya secara konkret sambil bermain. Penelitian ini memberi ide efisien tentang cara mengenalkan number sense di taman kanak-kanak secara multisensori dan diperlukan penelitian lanjutan tentang implikasi media ini pada kemampuan matematika anak di sekolah dasar.
The Difference Between Winners and Losers in Balanced Handball Games in the Final 10 Minutes
Authors:   Physical Activity, Physical Education, Sport and Health Research Centre, Sports Science Department, School of Social Sciences, Reykjavik University, Reykjavik, Iceland - Faculty of Kinesiology, University of Split, Split, Croatia, Þorgeirsson Sveinn , Pic Miguel ,   Institute of Sport, Tourism, and Service, South Ural State University, Chelyabinsk, Russia; Motor Action Research Group (GIAM), Lozano Demetrio ,   Health Sciences Faculty, VALORA Research Group, Universidad San Jorge, Zaragoza, Spain, Sigurgeirsson Olafur ,   HBStatz Company, Reykjavik, Iceland, Sekulic Damir ,   Faculty of Kinesiology, University of Split, Split, Croatia, Saavedra Jose M. ,   Physical Activity, Physical Education, Sport and Health Research Centre, Sports Science Department, School of Social Sciences, Reykjavik University, Reykjavik, Iceland
Published: November 2022

The objectives of this study are to analyze handball game-related statistics in balanced games (0-2 goal dif- ference at minute 50) in the final 10 minutes regarding the final outcome of winning or losing. i) Analyse statistical differences between winners and losers in male and female top Icelandic handball leagues and ii) calculate a discriminating model for performance variables for both male and female top Icelandic handball leagues. The game-related statistics from the final 10 minutes of 127 games from two seasons (85 male and 42 female) with a goal difference of two or fewer at minute 50 were analyzed. The internal consistency and reliability ranged from good to excellent for the games of both sexes. Differences between winning or losing for each sex were determined using the unpaired t-test or Mann-Whitney U test, and Cohens d for effect sizes was calculated. The results for males include four variables with large effect sizes and six with significant dif- ferences. The discriminatory model selected technical fouls and goalkeeper blocked shots from 9 m to classify 40.4% correctly (Wilks’ lambda 0.005, and canonical correlation of 0.997). For females, findings align with pre- vious research underscoring the importance of 9 m shots at goal at this level. However, they differ somewhat from full game statistics at the elite level with no difference in red cards and 7 m shots. Coaches should pay particular attention in tactical preparation to shots outside 9 m – both offensively and defensively in balanced games in the final 10 minutes.
Effectiveness of a Training Program in Improving Scientific Writing Skills Based on APA 7 Style among Postgraduate Students
Authors: Gaber Sherif Adel , Ali Sayed Ibrahim
Published: November 2022

Scientific writing is the final product of research and can take the form of a master’s or doctoral thesis or a peer reviewed journal article. It must follow the appropriate format and style of scientific writing. We verify the effectiveness of a training program in improving the scientific writing skills of 26 postgraduate students at King Faisal University's College of Education. A quasi-experimental approach was used. The sample was divided into 13 experimental group and 13 control group. A scientific writing skills scale and training program (both developed by the researchers) were used. The results showed that there was a statistically significant difference between the mean ranks of the experimental and control groups on the post-test in favor of the experimental group. The results also revealed a statistically significant difference between the mean ranks of the experimental group on the pre-and post-tests in favor of the post-test, the findings of the study indicate that the training program was effective in improving the scientific writing skills of the participants.
PROGRAM FOR PREVENTION OF THE USE OF PSYCHOACTIVE SUBSTANCES IN A SCHOOL ENVIRONMENT „I HAVE A PERSON“
Authors:   Sofia University „St. Kliment Ohridski“, Sofia, Donkova Emiliya , Ganeva Yana ,   Sofia University „St. Kliment Ohridski“, Sofia
Published: November 2022

This article presents a variant of the program for prevention of the use of psychoactive substances among adolescents, applicable in the educational space at the junior high school level (grades 5-7). The aim of the program is to raise awareness of the growing scale of the problem – both among students and among their teachers and parents; as well as to provide a practically oriented conceptual concept for its prevention. At the heart of the development is the emphasis on communication at different levels (intellectually, emotionally, cognitively) within a social group. The draft program is based on the conceptual ideas of the mutual learning method in the original developed by the team of Andrew Bell and Joseph Lancaster and later developed in the modern method „peers teach peers“, I apply in a number. In addition, the content of the program includes the use of various discussion and interactive methods in working with individual actors involved in the process. The specific methods have been chosen in order to achieve more effective results, taking into account the specific characteristics of the target groups and the wide scale of the problem. The program consists of several separate modules, each of which covers the work at a different stage – teacher training, parent training, student training. The use of questionnaires provided to the participants after the end of each stage is set as a tool for evaluating the efficiency.
INTEGRATION OF THE LANGUAGE COMPETENCE OF STUDENTS-FUTURE PRIMARY SCHOOL TEACHERS IN THE PRACTICAL PREPARATION IN METODICS IN EDUCATION OF NATUREKNOWLEDGE
Authors:   Shumen University „Bishop Konstantin Preslavski“, College – Dobrich, Yordanova Kameliya , Tsankova Milena ,   Shumen University „Bishop Konstantin Preslavski“, College – Dobrich
Published: November 2022

The moving factor for positive change and development in the educational system are well-trained and motivated teachers. The aim is to present the possibilities for integrating the students’ language competencies – future primary teachers, in their preparation in methodics in education in natureknowledge with a view to developing professional competences for the realization of cross-curricular connections in the lesson on Homeland Studies, Environment and Man and Nature. It is working on the application of the integrative connections in the lesson regard to: orthoepy; orthography and calligraphy; riddles; fables; tales; poems; story; elaboration and application of didactic procedures – communicative, linguistic and synthetic exercises; selecting texts in the lesson; comparison of objects, phenomena and events; application of confirmed pedagogical practices and various forms of work. The realization of integrative relationships between the disciplines studied by the students helps to increase the competencies and the future effectiveness in their professional realization.
YOL ŞİDDETİNDE SİLAH ETKİSİNİN ROLÜ: BİR DERLEME
Authors: AKTAŞ Alev
Published: November 2022

Sıklıkla sürücüler arasında yol vermeme gibi nedenlerden dolayı trafikte yaşanan sözlü veya fiziksel şiddet, trafik güvenliğini tehdit ederek ciddi boyutlara ulaşmaktadır. Bu durum “road rage (yol şiddeti)” kavramıyla alanyazında karşımıza çıkmaktadır. Yol şiddeti hakkında yapılan bazı araştırmalar, aracında silah bulunduran sürücülerin saldırgan davranışlar sergileme eğilimi açısından daha riskli olabileceğini göstermiştir. Bu davranışlar üzerinde sosyal psikolojide “silah etkisi (weapons effect)” diye anılan kavramın etkili olabileceği öne sürülmüştür. Bu çalışma ile, trafik ortamında sergilenen saldırgan davranışları etkilediği düşünülen faktörlerden silah etkisi üzerinde durularak, bu etki ile yol şiddeti arasındaki ilişkiye dair alanyazında yapılan araştırma bulguları üzerinden bir değerlendirme yapmak amaçlanmıştır. Konu, sosyal psikoloji ve trafik psikolojisi perspektifiyle trafik güvenliği kapsamında ele alınmıştır.
Belarus-Poland Migration Crisis and Supra-National Political Concerns of the Extended Actors
Authors: ERDOĞAN Zahide , KARAKOÇ DORA Zuhal
Published: November 2022

This study seeks to examine the sociological, political, and humanitarian dimensions of the Belarus-Poland migration crisis and aims to discuss the differences between migration diplomacy and state-organized-engineered migration within the framework of the instrumentalization and weaponization of migrants. Statements made by EU authorities about the Belarus-Poland migration problem, sanctions, and measures implemented are investigated to evaluate the EU’s approach. Furthermore, in order to comprehend Belarus’ perspective, Lukashenko’s statements and press coverage of the incident are scrutinized. Theoretically, while following a descriptive analysis method, the article considers how Belarus-Poland border issue has given rise to a great deal of media interest due to Belarus’s balance and interest-oriented policies oscillating between the former Soviet world and the West and argues how Russia brought a global dimension to the issue as a result of its historical political pursuits. Finally, it concludes that the migration crisis between Belarus and Poland is not a simple crisis that concerns two countries, if anything, it is a reflection and precursor of multi-actor global politics serving different purposes in the region.
Assessment of Road Network Connectivity in Support of New Capital Development
Authors: Junaidi . , Adisasmita Sakti A. , Pallu Muhammad S. , Ramli M. Isran
Published: November 2022

The shifting of the capital of Indonesia from Jakarta to East Kalimantan, or East Borneo, is underway. There are certain to be new issues that arise as a result of this migration. The state of the nation's current transportation infrastructure is one of the most prominent right now. The new capital of Indonesia, Jakarta, is situated in the midst of a jungle. For this reason, the road network should be established before, or at least concurrently with, the IKN construction. It is critical to understand the direction of future growth in the IKN region before developing a road network architecture. Potential partner locations might potentially benefit from enhanced access and connection to the existing road network in this situation as well. To ensure that the IKN is able to work properly and link additional nodes, many partner area points are being considered. A literature review, a focus group discussion, and in-depth interviews were conducted to come up with a development plan for IKN partner regions and highlight areas of special concern. It was also determined if the addition of a new node had a positive impact by utilizing a connection matrix and the accessibility index. Most linkages are found at five of the 26 nodes in the complete connectivity matrix of national highways around IKN in East Kalimantan. Node 3 and Node 7 are the most accessible and easy-to-access component nodes of the road network, compared to other nodes. Doi: 10.28991/CEJ-2022-08-10-011 Full Text: PDF
SENTIMENT ANALYSIS ON YOUTUBE SMART PHONE UNBOXING VIDEO REVIEWS IN SRI LANKA
Authors: Sally Sherina
Published: November 2022

Product-related reviews are based on users’ experiences that are mostly shared on videos in YouTube. It is the second most popular website globally in 2021. People prefer to watch videos on recently released products prior to purchasing, in order to gather overall feedback and make worthy decisions. These videos are created by vloggers who are enthusiastic about technical materials and feedback is usually placed by experienced users of the product or its brand. Analyzing the sentiment of the user reviews gives useful insights into the product in general. This study is focused on three smartphone reviews, namely, Apple iPhone 13, Google Pixel 6, and Samsung Galaxy S21 which were released in 2021. VADER, which is a lexicon and rule-based sentiment analysis tool was used to classify each comment to its appropriate positive or negative orientation. All three smartphones show a positive sentiment from the users’ perspective and iPhone 13 has the highest number of positive reviews. The resulting models have been tested using Naïve Bayes, Decision Tree, and Support Vector Machine. Among these three classifiers, Support Vector Machine shows higher accuracies and F1-scores.
CONSIDERATIONS AND CONUNDRUMS THAT CONFRONTED THROUGHOUT THE RECRUITING PROCESS
Authors: Mishra Anjay Kumar , Aithal P. S.
Published: November 2022

Purpose: The act of hiring a new employee may have significant repercussions for an organization on both the ethical and legal fronts. Let’s compile a list of some of the most prevalent ethical considerations and conundrums that human resource professionals confront throughout the recruiting process.Design/Methodology/Approach: A survey of the current literature discovered various areas of significance for both scholastics and recruiting executives and other employees. This is conceptual literature-based research. This was done with the intention of better identifying the concepts that impact employment selection ethics and hiring practices. Previous scholars have asserted that the moral duty, diversity, antidiscrimination, integrity, and employment justice all play a role in the hiring anytime new people is being brought on board.Findings/Result: Mindfulness and activity here will prompt inspiring elements that may influence attitudes, while ethical hiring practices will be allowed to create the culture of the organization. This article provides a concept of knowing that when institutions apply stated ethical hiring criteria, employers are more likely to attract and hire ethical applicants. This dichotomy of knowledge is presented in the form of a paradox. This conception gives rise to the presumption that managers are required to fulfill the organization of ethical gatekeepers for the organizations to which they belong.Originality/Value: A comprehensive examination of Ethics in Human Resource Management as a Case of considerations and conundrums that human resource professionals confront throughout the recruiting process will enable to empower as we are lacking corporate culture here in Nepal highlights the empirical assessment on the issues in depth.
Quantum-chemical modeling of doxorubicino-fullerenol agents of cancer therapy
Authors: Dikusar E. A. , Pushkarchuk A. L. , Bezyazychnaya T. V. , Akishina E. A. , Soldatov A. G. , Kuten S. A. , Stepin S. G. , Nizovtsev A. P. , Kilin S. Ya. , Kulchitsky V. A. , Potkin V. I.
Published: November 2022

In order to therapeutically destroy neoplasms, chemotherapy or radiotherapy is usually applied, and in isotope medicine short-lived radionuclides are injected into the tumor (59Fe, 90Y, 95Zr, 99mTc, 106Ru, 114*In, 147Eu, 148Eu, 155Eu, 170Tm, 177mLu, 188Re, 210Po, 222Rn, 230U, 237Pu, 240Cm, 241Cm, 253Es). Binary (or neutron capture) therapy is a technology designed to selectively treat malignant tumors and using drugs tropic to tumors containing non-radioactive nuclides (10B, 113Cd, 157Gd at al.). Triadic therapy is the sequential introduction into the body of a combination of two or more separately inactive and harmless components, tropic to tumor tissues and capable of selectively accumulating in them or entering into chemical interaction with each other and destroying tumor neoplasms under certain sensitizing external influences. The aim of this work is to quantum-chemically simulate the electronic structure and to analyze the thermodynamic stability of new doxorubicino-fullerenol agents for the treatment of tumor neoplasms. The need for preliminary studies on the modeling of such objects is due to the extremely high labor intensity, cost and complexity of their practical production.
Influence of rosin resin acids amides on the strength of interfiber bonds in paper in the z-direction
Authors: Fleisher V. L.
Published: November 2022

Resin acid amides of rosin, depending on the structure, can have both a hydrophobizing and hardening effect on paper pulps. It has been established that the developed products of rosin modification (adhesive rosin composition TMAS3N and polyamide resin ProChem DUO) containing amides of resin acids, when introduced into paper pulps made from fibrous suspensions of sulphate cellulose (unbleached and bleached) of coniferous and broad-leaved species and waste paper, different in the degree of grinding (25, 40 and 70 °ShR), contribute to the increase in the strength of interfiber bonds in paper in the z-direction. The effect of the TMAS-3N emulsion was compared with the traditionally used TM and AKD sizing emulsions. The introduction of the TMAS-3N emulsion into paper pulps (0.40 % of a. d. w.) provides the maximum increase in the strength of interfiber bonds in paper in the z-direction made from cellulose, equal to 16.7–88.6 %, and from waste paper – 19.4–75.4 %, which is 1.6–6.4 and 2.3–4.5 times more compared to TM emulsion, respectively. The achieved positive effect is due to the presence in the TMAS-3H emulsion of particles of the dispersed phase of hydroxyethylamides and aminoethyl ethers capable of forming hydrogen bonds with hydroxyl groups on the mating surfaces of cellulose fibers. Sizing paper stocks with AKD emulsion reduces the strength of interfiber bonds in paper in the z-direction over the entire range of paper content studied. Polyamide resin ProChem DUO, which is a polyaminoamide of rosin resin acids, at its content in paper stocks of 0.10 %, increases the strength of interfiber bonds in paper in the z-direction, made from cellulose and waste paper suspensions, by 50.0–92.3 and 44.4–63.5 %, respectively. The obtained results of increasing the strength of interfiber bonds in paper in the z-direction by resin acid amides of rosin are in full agreement with the mechanism of bridged bonds and the theory of hydrogen bonds.
Composite technology for the production of paper and cardboard including synthetic fibers
Authors: Eshbaeva U. Ja. , Djalilov A. A.
Published: November 2022

In the modern world, the importance and volumes of packaging produced are constantly increasing. It is a powerful means of promoting goods on the market, but at the same time, the role of its quality increases. Currently, paper and paperboard packaging is not only a significant part of paper and paperboard market in general, but also a large part of the world’s packaging consumption. Currently, the world pays special attention to the use of secondary paper waste for the production of paper and cardboard and increase the volume of their processing. The article is devoted to the production of new types of multilayer paper and cardboard with the addition of chemical fiber and secondary waste, as well as high-quality paper and cardboard that can be used in the printing industry, in order to save valuable cotton cellulose in the country. However, the article shows in what proportions it is advisable to use secondary fibers in combination with cellulose in the production of multilayer composite paper and cardboard for the printing and paper industries.
Vitamin D status during the COVID-19 pandemic: the experience of Russia and Belarus
Authors: Karonova T. L. , Rudenco E. V. , Radaeva O. A. , Chernikova A. T. , Golovatyuk K. A. , Shlyakhto E. V.
Published: November 2022

During the COVID-19 pandemic, a high prevalence of vitamin D deficiency and insufficiency remains. Thus, the studies carried out on the territory of the Russian Federation (RF) and the Republic of Belarus over the last 3 years have shown the prevalence of vitamin D deficiency and insufficiency in the population, regardless of the gender of examined persons, the geographic location and the season of the year. Taking into account the known immunomodulatory functions of serum 25(OH)D, the aim of this review was to assess the data that were accumulated in the world, Russia and Belarus and were concerned with a possible contribution of vitamin D deficiency to COVID-19 infection, course and prognosis, as well as with the role of cholecalciferol therapy in prevention and treatment of the disease. Most of the studies demonstrate a negative association between the serum 25(OH)D level and COVID-19 severity and/or mortality. Previously, it has been shown that the serum 25(OH)D level less than 11.4 ng/ml is associated with an increased risk of COVID-19 mortality. At the same time, the results of the studies using cholecalciferol therapy for COVID-19 prevention and treatment are conflicting. Intervention  studies in the Russian Federation and the Republic of Belarus are scanty; however, the available data indicate a possible  benefit of therapy, which allows it to be considered as an addition to the main methods of treating COVID-19.
The Governments’ Use of Social Networking Sites (SNS) to Promote Citizens’ Trust During the COVID-19: Perceived Religious Values as a Moderator
Authors: Achmad Mansyur , Ashariana  , Nurkadarwati
Published: November 2022

Grounded on the social capital theory, the current study examines the direct and indirect association of perceived government response to COVID-19 and the interaction of government representatives on social networking sites with the Public Trust in Government (PTIG) via perceived e-governance effectiveness as a mediator. Moreover, the interactive effect of Perceived Religious Value with Perceived Government Response to COVID-19 and Interaction of Government Representatives on Social Networking Sites was assessed to enhance public trust in government. Two independent studies were performed, and data were evaluated using SmartPLS 3.0 software. Results revealed the significant direct and indirect impact of Perceived Government Response to COVID-19 and Interaction of Government Representatives on Social Networking Sites on Public Trust in Government via Perceived E-governance Effectiveness as a mediator. The results also supported the moderating role of Perceived Religious Value between the Interaction of Government Representatives on Social Networking Sites and Public Trust in Government. Likewise, the findings supported the interactive effect of Perceived Government Response to COVID-19 with Perceived Religious Value to enhance Public Trust in Government. Key policy insights about the government’s timely and effective response to COVID-19 and Social Networking Sites used to enhance public trust are highlighted.
V International scientific and practical conference "The traditions of I. I. Sreznevsky in Russian lexicology and lexicography of the XXI century. To the 210th anniversary of the birth of Academician I. I. Sreznevsky"
Authors: Kolgushkina N. V. , Nikitin O. V.
Published: November 2022

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The Effectiveness of Using Problem-Based Learning (PBL) in Mathematics Problem-Solving Ability for Junior High School Students
Authors: Marchy Febrinna , Murni Atma , Kartini Kartini , Muhammad Ilham
Published: November 2022

This study aims to determine the effectiveness of the Problem Based Learning model in improving students' problem solving abilities. This is a quasi-experimental study using the Nonequivalent Pretest-Posttest Control Group Design. Students in seventh grade at SMP Negeri 32 Pekanbaru comprised the whole study population. In this research, the sample comprised two classes: VII3 as the experimental class and VII1 as the control class. This study utilizes the beginning mathematical ability test (KAM) and the mathematical problem-solving ability test as its instruments. The class of the sample was determined using the KAM test findings. The data were evaluated using the similarity test of two independent sample t-tests, which was preceded by tests for normality and homogeneity of variance. Students who participated in Problem-Based Learning had greater growth in their ability to solve mathematical problems than students who participated in conventional learning.
Theology of Baku Kele: A Contextual Constructive Theology for A Post-Communal Conflict
Authors: Sinaga Rouli Retta Trifena , Saimima Johan Robert
Published: November 2022

After communal conflict happened in Maluku in 1999-2004, Larike’s Christian society hasproblematic social relationship with Larike’s Moslem society. Baku kele as a cultural fraternal wisdom of Larike’s society is rarely donein Larike. Therefore, through this paper we try to offer theology of baku kelefor them. By understanding baku keletheologically as care to others and social lifestyle, this will have implications for social relationship reconstruction carried out by The Protestant Church of Maluku in Larike. Here the theology of baku keleis constructed from stories of communal conflict effects to Larike’s Christian society conveyed by them, cosmological view of Larike’s society,biblical basis of Luke 10:25-37, and some contemporary theological ideas.This paper is to propose a small contribution to The Protestant Church of Maluku’s contextual theology forrestoring social relationship post-communal conflict through an open existence continually.
Pentingkah Pengaruh Lingkungan Kerja Disiplin Dan Motivasi Terhadap Kepuasan Kerja Karyawan
Authors: Hamdan  , Amarul  , Gentari Ratu Erlina
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh lingkungan kerja, disiplin, dan motivasi terhadap kepuasan kerja karyawan pada PT Elnusa Fabrikasi Konstruksi di Kota Cilegon. Penelitian ini dilakukan dengan menggunakan metode penelitian kuantitatif. Populasi penelitian dilakukan pada PT Elnusa Fabrikasi Konstruksi di Kota Cilegon berjumlah 52 orang, dan diambil sampel menggunakan sampel jenuh. Penelitian dilakukan pada PT Elnusa Fabrikasi Konstruksi di Kota Cilegon sejak 19 November 2021 sampai dengan 19 Agustus 2022. Data dikumpulkan dengan angket (kuesioner), dan dianalisis dengan aplikasi SPSS versi 25. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat pengaruh yang signifikan antara lingkungan kerja dan kepuasan kerja karyawan, terdapat pengaruh yang signifikan antara disiplin kerja dan kepuasan kerja karyawan, terdapat pengaruh yang signifikan antara motivasi kerja dan kepuasan kerja karyawan, dan terdapat pengaruh yang signifikan antara lingkungan kerja, disiplin, dan motivasi secara bersamaan terhadap kepuasan kerja karyawan. peneliti yang akan melakukan penelitian pada lokasi yang sama dengan penelitian ini, sebaiknya menggunakan variabel lain yang belum diteliti pada lokasi yang sama untuk mengembangkan penelitian.
Pengaruh Iklim Organisasi Dan Kedewasaan Individu Pegawai Terhadap Kinerja Pegawai Pada Dinas Badan Pengelola Keuangan Dan Aset Daerah (Bpkad) Kabupaten Serang
Authors: Nafiuddin  , Deviyantoro  , Ali Murad Anizir
Published: November 2022

Kinerja Pegawai dapat dipengaruhi oleh banyak faktor diantaranya Iklim Organisasi dan Kedewasaan. Objek penelitian ini Badan Pengelola Keuangan dan Aset Daerah Kabupaten Serang. Tujuan penelitian ini untuk mengetahui pengaruh Iklim Organisasi dan Kedewasaan Individu terhadap Kinerja Pegawai Badan Pengelola Keuangan dan Aset Daerah Kabupaten Serang. Sampel penelitian ini berjumlah 59 responden yang disebar kepada Pegawai Badan Pengelola Keuangan dan Aset Daerah Kabupaten Serang. Metode analisis yang digunakan metode kuantitatif, analisis yang digunakan adalah uji asumsi klasik, analisis regrensi linear berganda, koefisien determinasi dan uji hipotesis yang menggunakan spss v.24 for windows. Berdasarkan hasil penelitian dapat disimpulkan bahwa: 1) Iklim Organisasi yang berpengaruh signifikan terhadap kinerja karyawan, 2) Kedewasaan Individu tidak terdapat pengaruh yang signifikan terhadap kinerja karyawan, dan 3) Iklim Organisasi dan Kedewasaan Individu secara bersama-sama (simultan) berpengaruh signifikan terhadap kinerja karyawan. Dengan nilai koefisien determenasi sebesar 0,261% dan sisanya sebesar 73,9% dipengaruhi oleh faktor lain yang tidak di teliti oleh peneliti
Upaya Peningkatan Kinerja Karyawan Melalui Lingkungan Kerja Non Fisik, Loyalitas Kerja Dan Pay Satisfaction
Authors: Andari  , Nafiudin  , Ramadhanty Dita Qur’aini
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh Lingkungan Kerja Non Fisik, Loyalitas Kerja dan Pay Satisfaction terhadap Kinerja Karyawan. Penelitian ini menggunakan objek perusahaan PT Samator Gas Industri Cilegon. Metode penelitian ini yaitu kuantitatif dengan data yang dikumpulkan merupakan data primer melalui kuesioner yang diberikan kepada karyawan. Alat analisis yang digunakan untuk menguji hipotesis adalah IBM SPSS V25. Metode pengambilan sampel yang digunakan yaitu sampel jenuh sebanyak 40 responden. Teknik analisis yang digunakan yaitu uji instrument, uji asumsi klasik, analisis regresi linear berganda, koefisien determinasi, uji parsial t, dan uji simultan F. Hasil penelitian secara parsial menyimpulkan bahwa terdapat pengaruh antara variabel Lingkungan Kerja Non Fisik terhadap Kinerja Karyawan, terdapat pengaruh secara signifikan antara variabel Loyalitas Kerja terhadap Kinerja Karyawan, dan tidak terdapat pengaruh secara signifikan antara variabel pay satisfaction terhadap Kinerja Karyawan. Hasil penelitian secara simultan menunjukkan nilai F hitung > F tabel (3.898 > 2.859) dengan demikian Ho ditolak dan Ha diterima dengan tingkat signifikan 0,016 < 0,05 maka dapat disimpulkan bahwa terdapat pengaruh yang signifikan antara Lingkungan Kerja Non Fisik (X1), Loyalitas Kerja (X2) dan Pay Satisfaction (X3) terhadap Kinerja Karyawan (Y)
TOPLUM 5.0 VE İNSAN KAYNAKLARI YÖNETİMİ İLİŞKİSİ
Authors: KAÇİK Selda , AYKAN Ebru
Published: November 2022

Günümüzde, her geçen gün önemi artan Bilgi Toplumu’nun Süper Akıllı Toplum’a dönüşümü gerçekleşmektedir. Süper Akıllı Toplum, kısaca Toplum 5.0 olarak adlandırılmaktadır. Toplum 5.0, insanların teknoloji ile ilişkisinden en üst düzeyde verim alındığı bir toplum modeli olarak yorumlanmaktadır. Öyle ki, bir toplumu teknolojiden en iyi şekilde faydalanmaya hazırlarken geliştirilebilecek strateji, nitelikli insan kaynağına duyulan ihtiyacı gidermektir. Bunun için ise, karşı karşıya olduğumuz bu yeni dönemde, doğru bir insan kaynakları yönetimi (İKY) süreci uygulamak gerekmektedir. Toplum 5.0'a İKY açısından bakıldığında ise, dijitalleşmenin getirdiği işgücü piyasasındaki değişimlerin önemli sorunlara yol açabileceği görülmektedir. Toplum 5.0’ın beraberinde getirdiği yeniliklerin yanı sıra örgüt ve bireylerin bu teknolojiyi kullanabilir, uygulayabilir ve geliştirebilir niteliklere sahip olması gerekmektedir. Bu noktada bu çalışmanın amacı, Toplum 5.0 ve İKY ilişkisini açıklamaktır. Diğer yandan Toplum 5.0’ın hayata geçirilmesinde İKY’nin eş zamanlı olarak gelişim göstermesi gerekmektedir. Bu çalışma ile bu konuda farkındalık oluşturmak da hedeflenmektedir.
DIŞ BORÇLARIN SÜRDÜRÜLEBİLİRLİĞİ: KIRILGAN BEŞLİ ÜLKELERİ PANEL EŞBÜTÜNLEŞME ANALİZİ
Authors: AKIN Tuğba , GÜNEŞ Sevcan
Published: November 2022

Küresel kriz ve Covid-19 pandemi etkisiyle yaşanan ekonomik daralma sonrası uygulanan genişletici para ve maliye politikaları sebebiyle borç sürdürebilirliği kavramı tüm ulusal ekonomilerin öncelikli sorunu haline gelmiştir. Bu bağlamda ödemeler dengesindeki ekonomik kırılganlıkları sebebiyle konunun özellikle Hindistan, Brezilya, Meksika, Güney Afrika ve Türkiye için analiz edilmesinin önemi artmıştır. Bu çalışmada özellikle makroekonomik değişkenlerdeki sorunlarının benzerlik göstermesi nedeniyle kırılgan beşli olarak da adlandırılan bu ülkelerin, borçlarının sürdürebilirliği Hakkio ve Rush (1991), Sawada (1994) ve Önel ve Utkulu (2006) metodolojisi kullanılarak 2001-2019 dönemi için analiz edilmiştir. Modelde; dış ticaret dengesi, merkez bankası döviz rezervlerindeki değişim, net cari transferler ve toplam borçlar üzerindeki faiz maliyeti (Libor ve CDS) verileri kullanılarak dış borç yaratan ve azaltan değişkenler arasındaki eşbütünleşme ilişkisi Panel ECM testi (Westerlund, 2007) ile incelenmiştir. Elde edilen panel eşbütünleşme katsayı tahmin sonuçlarına göre analiz edilen ülkeler için zayıf dış borç sürdürebilirliği bulunmuştur. Ülke bazında yapılan analiz sonuçları ise, sadece Meksika’nın dış borçlarının güçlü bir şekilde sürdürebilir olduğunu, CDS primi diğer ülkelere göre yüksek olan Türkiye’nin ise en zayıf dış borç sürdürebilir ülke olduğunu göstermiştir.
TÜRK TARIM SEKTÖRÜNÜN KENDİ KENDİNE YETERLİLİK VE GIDA GÜVENCESİ AÇISINDAN DEĞERLENDİRİLMESİ: BÜTÜNLEŞİK VZA/AHP ANALİZİ
Authors: SOYHAN Sinem , MOLLAVELİOĞLU Muhammed Şükrü
Published: November 2022

Bu çalışmanın temel amacı, kamuoyunda sıklıkla dile getirilen Türk tarım sektörünün kendi kendine yeterlilik özelliğini kaybettiğine yönelik tartışmalar üzerine, Türk tarım sektörünün kendi kendine yeterliliğini ve gıda güvencesi açısından durumunu değerlendirmektedir. Bu açıdan çalışma, “Türk tarım sektörünün kendi kendine yeterliliği ve gıda güvencesini sağlayabilmekte midir?” sorusunu cevaplamaya çalışmaktadır. Bu amaçla kendi kendine yeterlilik, öncelikle ürün sınıflarının yeterlilik derecesi üzerinden incelenmekte, daha sonra kalori gereksinimlerinin karşılanması oranından hareketle incelenmektedir. En son olarak Küresel Gıda Güvencesi İndeks (Global Food Security Index - GFSI) çalışmasının 2019 verilerinden hareketle bütünleşik VZA / AHP yaklaşımı kullanılarak gıda güvencesi açısından Türk tarımı 30 OECD ülke örnekleminden hareketle incelenmektedir. Elde edilen bulgular incelendiğinde, kuru baklagiller, tahıl toplamı ve diğer tahıllar toplamı açısından üretimin artırılmasının kendi kendine yeterlilik açısından gerekli olduğu görülmektedir. Benzer şekilde sığır eti, ayçiçeği ve pirinç gibi ürünlerde son yıllarda gözlemlenen üretim artışlarının devamlılığının sağlanması gerekmektedir. Gıda güvencesi açısından ise özellikle satın alınabilirlik ve doğal kaynak ve dayanıklılık boyutlarına yönelik iyileştirici politikaların benimsenmesi önem arz etmektedir.
ÇOKLU YAPISAL KIRILMALAR ALTINDA ENFLASYON İLE ULUSLARARASI PETROL FİYATLARI İLİŞKİSİ: TÜRKİYE ÖRNEĞİ
Authors: KARTAL Gökhan
Published: November 2022

Bu çalışmada, Türkiye'de yapısal kırılmalar altında uluslararası petrol fiyatları ile enflasyon arasındaki uzun dönemli ilişki 1960-2020 dönemi verileri kullanılarak analiz edilmektedir. Bu doğrultuda Carrion-i-Silvestre vd. (2009) tarafından önerilen çoklu yapısal kırılmalı birim kök testi ile Maki (2012) tarafından önerilen çoklu yapısal kırılmalı eşbütünleşme testleri kullanılmıştır. Önemli yapısal kırılma tarihlerinin raporlandığı çoklu yapısal kırılmalı bu testler sonucunda, Engle-Granger (1987) eşbütünleşme testinin aksine, yapısal kırılmalar altında Türkiye’de enflasyon ile petrol fiyatları arasında eşbütünleşme ilişkisinin varlığı tespit edilmiştir. FMOLS test sonuçlarına göre, uzun dönemde Türkiye’de petrol fiyatlarındaki %1 artış enflasyonu yaklaşık olarak %0,52 artırmaktadır. Kısa dönemde ise petrol fiyatlarındaki %1 artış enflasyonu yaklaşık olarak %0,35 artırmaktadır. Bu sonuçlar, yapısal kırılmalar altında Türkiye’de uzun dönemde petrol fiyatlarının enflasyona ılımlı derecede geçişkenliğinin varlığını göstermektedir.
Studies of ternary systems of sulfadiazine with β-cyclodextrin and aminoacids
Authors: Delrivo Alicia , Granero Gladys , Longhi Marcela
Published: November 2022

Introduction: Cyclodextrins (CD), are known to form inclusion complexes with a variety of guest molecules both in solution and in the solid state. This can lead to the alteration of properties of guest molecules. Unfortunately, the complexation efficiency of CD is rather low, and can be enhanced by formation of ternary complexes using aminoacids (AA). Sulfadiazine (SDZ) is an antibiotic with extremely low water solubility which limits its therapeutic applications and bioavailability. Objetives: The aim of this work was to increase the aqueous solubility of SDZ by preparing ternary complexes of this drug with β-cyclodextrin (βCD) and an AA as a third auxiliary substance. Materials y Methods: Complex formation was studied by phase solubility analysis (PSA), nuclear magnetic resonance (NMR), differential scanning calorimetry (DSC), thermogravimetric analysis (TG) and scanning electron microscopy (SEM). Results: The apparent stability constants (KC) of the multicomponent complexes were calculated from the solubility diagrams. By the analysis of the NMR spectra, it could be said that the shifts of some protons evidenced the important role of the AA in the formation of multicomponent complexes. Among the AA, Arginine (ARG) proved to have better solubilizing properties for SDZ, reaching an improvement up to 70 times. The use of DSC, TG and SEM suggested the formation of new solid phases between SDZ:βCD:AA. Conclusions: As a result of this research, it was determined that ternary products were more effective in improving drug solubility than the corresponding SDZ:βCD binary system.
Estudio de la actividad antioxidante y antitumoral del propóleo
Authors: Del Río del Rosal Elisa , Casas Arrojo Virginia , Gómez Turpín Eva M. , Gil Gómez José , Abdala Díaz Roberto , Figueroa Félix L.
Published: November 2022

Introducción: El propóleo es la sustancia que protege a la colmena, es una resina de composición compleja y viscosa que las abejas utilizan en la reparación y protección de la colmena. El material del que procede el propóleo son las resinas, brotes y pecíolos de las hojas de diferentes vegetales, por ello presenta una composición química muy compleja que varía en función de la flora de recolección de las abejas. Posee capacidad antimicrobiana, antiinflamatoria que está relacionada con su poder antioxidante, inmunomoduladora, entre otras. Objetivos: En este trabajo se estudian las actividades antioxidantes y antitumorales de propóleos de distintas zonas de la provincia de Málaga comparándolos con uno de la región de Bohemia al sur de la República Checa. Material y métodos: La actividad antioxidante se evaluó según el método ABTS+/S2O8K2. Además se estimó la cantidad de proteínas totales a partir del contenido de nitrógeno y posteriormente se determinó la citotoxicidad y actividad antitumoral del propóleo del Puerto de la Torre, al norte de Málaga, según el método del bromuro de 3-(4,5-dimetiltiazol-2-il)-2,5-difenil tetrazolio. Resultados: Se observó que el propóleo presenta una elevada actividad antioxidante, aunque tiene una menor cantidad de proteínas. El propóleo presenta elevada toxicidad y mayor actividad antitumoral frente al cáncer de colon que al de leucemia. Conclusión: Con todos estos datos obtenidos se puede concluir que el propóleo presenta diferentes actividades de interés para la industria alimentaria o cosmética, entre las que destaca su elevado poder antioxidante y su capacidad como antitumoral.
Anticoagulant properties of a high molecular weight polysaccharide fraction (1000RS) of the ascidian Microcosmus exasperatus
Authors: Restrepo-Espinosa Diana C. , Motta Juliana María , Teixeira Felipe Castro O. de B. , Román Yony , Colorado-Ríos Jhonny , Pavão Mauro S. G. , Martínez Alejandro
Published: November 2022

Aims: The anticoagulant effect and cytotoxicity of a high molecular weight polysaccharide fraction (1000RS) obtained from the tunic of the ascidia Microcosmus exasperatus were evaluated. Methods: Anticoagulant properties of 1000RS was evaluated by activated Partial Thromboplastin Time (aPTT), Thrombin Time (TT), Prothrombin Time (PT), anti-factor Xa and lupic anticoagulant (dRVVT) assays. Cytotoxicity was tested on murine hematopoietic cells using MTT assay. Results: This galactose rich fraction showed to be a potential anticoagulant due to its inhibitory effect on the intrinsic coagulation pathway. At the same time, anticoagulant doses of this fraction have no effect on cellular viability, which means that it can be used as a therapeutic agent. Conclusion: In vitro anticoagulant effect of 1000RS occurs at innocuous doses, however, it still need to be tested using in vivo models and its cytotoxicity evaluated in normal human cell lines.