bluuebunny/crossref_metadata_2025 huggingface dataset:
TÌNH TRẠNG DINH DƯỠNG CỦA NGƯỜI BỆNH ĐỢT CẤP BỆNH PHỔI TẮC NGHẼN MẠN TÍNH TẠI BỆNH VIỆN PHỔI TRUNG ƯƠNG NĂM 2023
Authors: Trần Thị Thu Huyền , Phạm Thị Trang , Vũ Trung Nghĩa , Nguyễn Quang Dũng
Published: April 2024

Mục tiêu: Đánh giá tình trạng dinh dưỡng trên người bệnh đợt cấp bệnh phổi tắc nghẽn mạn tính (COPD).
Phương pháp: Nghiên cứu mô tả cắt ngang được tiến hành trên 142 người bệnh, chọn mẫu thuận tiện, thu thập số liệu nhân trắc, hoá sinh, đánh giá tình trạng dinh dưỡng bằng chỉ số BMI và công cụ đánh giá tổng thể chủ quan SGA.
Kết quả: Tỷ lệ người bệnh thiếu năng lượng trường diễn là 37,3%. Tỷ lệ người bệnh có nguy cơ suy dinh dưỡng theo SGA là 86,6%, trong đó suy dinh dưỡng mức nặng (SGA-C) chiếm 11,2%. Tỷ lệ người bệnh có nồng độ albumin huyết thanh dưới 35 g/L ở nhóm SGA-C (43,8%) cao hơn đáng kể so với nhóm SGA-B (18,7%) và nhóm SGA-A (5,2%) với p = 0,015. Tỷ lệ người bệnh có nồng độ protein huyết thanh dưới 60 g/L là 7,0%.
Kết luận: Người bệnh đợt cấp COPD có nguy cơ suy dinh dưỡng cao, cần đánh giá tình trạng dinh dưỡng và can thiệp dinh dưỡng sớm để đề phòng suy dinh dưỡng và cải thiện hiệu quả điều trị.
NGHIÊN CỨU ỨNG DỤNG PROTEASE ĐỂ CHIẾT XUẤT PROTEIN THỦY PHÂN TỪ BÃ SỮA GẠO
Authors: Trần Hoàng Quyên , Lê Viết Hùng , Nguyễn Minh Châu , Vũ Đức Mạnh , Lê Văn Bắc , Phạm Phạm Linh Khoa
Published: April 2024

Mục tiêu: Xác định các thông số tối ưu cho quá trình chiết xuất protein từ bã sữa gạo đã làm sạch tinh bột và carbohydrate bằng enzyme protease thương phẩm
Phương pháp: Nghiên cứu được thực hiện trên cơ sở khảo sát lựa chọn 9 loại enzyme thương phẩm của công ty Amano-Nhật Bản để tiến hành tối ưu hóa điều kiện enyzme hóa nhằm chiết xuất protein từ bã sữa gạo bằng phương pháp thiết kế bề mặt RSM, mô hình I-optimal. Sản phẩm của nghiên cứu được phân tích SDS-PAGE để đánh giá thành phần protein.
Kết quả: Đã lựa chọn được enzyme protin “Amano” SD-AY10 của công ty Amano-Nhật Bản có hiệu suất chiết xuất protein và mức độ thủy phân DH cao nhất trong các enzyme được đánh giá. Quá trình tối ưu hóa điều kiện thủy phân bằng SD-AY10 cho hiệu suất chiết xuất protein từ bã sữa gạo đạt 90,1%, điều kiện tối ưu là: nồng độ enzyme :1.2%E S, nồng độ muối (NH4)2SO4 2.5%, pH 8, tại 60°C trong 120 phút thủy phân, khối lượng protein trong dịch thủy phân đạt 19,1%DS. Kết quả phân tích SDS-PAGE cho thấy sản phẩm có hàm lượng peptide phân tử lượng chủ yếu dưới 100 kDa, chứng tỏ sản phẩm có tính chức năng và chất lượng dinh dưỡng cao, phù hợp ứng dụng trong sản xuất các sản phẩm thực phẩm, mỹ phẩm, dược phẩm sử dụng cho con người.
Kết luận: Kết quả nghiên cứu giúp đa dạng hóa sản phẩm từ phụ phẩm nông nghiệp, đặc biệt là từ gạo, hỗ trợ phát triển cho ngành công nghiệp chế biến và sản xuất thực phẩm bền vững.
Hadis, Tefsir ve Siyer İlişkisi Üzerine Bir Deneme
Authors: Oğuzay Rukiye
Published: April 2024

Hz. Peygamber’in söz, fiil ve takrirlerini konu edinen hadis ilmi, onun hayatını, mücadelesini, tebliğ faaliyetlerini ve savaşlarını ele alan siyer ilmiyle şüphesiz yakın bir irtibat içerisindedir. Her iki ilim de diğeri açısından kaynaklık değeri taşımaktadır. Kur’ân âyetlerini açıklama ve yorumlama ilmi olan tefsir ise âyetlerin nâzil olduğu dönemi konu edinen hadis ve siyer ilminden istifade ettiği gibi bu ilimlere katkı sağlaması bakımından son derece önemlidir. Dolayısıyla bu üç ilmi birbirinden bağımsız olarak ele almak doğru olmasa gerektir. Nitekim son zamanlarda hadis-siyer, hadis-tefsir, siyer-tefsir ilişkileri üzerine araştırmalar yapıldığı görülmektedir. Bu araştırma ise, örnek bir olay üzerinden üç disiplin arasındaki irtibatın irdelenmesi bakımından önem taşımaktadır. Hz. Peygamber’in görevlendirdiği bazı seriyyelerde İslâm’a girdiğini belirttiği halde öldürülen kimselerle ilgili haberler, araştırmanın temel konusunu teşkil etmektedir. Aynı konu merkezinde siyer-tefsir ilişkisi başka bir araştırmada ele alındığından burada ilgili meselenin hadis rivayetleri üzerinden tetkiki yapılmış, siyer ve tefsir kaynaklarından elde edilen veriler hadis kaynaklarındakilerle karşılaştırılmıştır. Böylece dönemle ilgili olayların ve meselelerin doğru tespiti noktasında hadis ilminin her iki alana ne gibi katkılar sağlayabileceği veya bu alanlardan nasıl yararlanabileceği örnek hadiseler merkezinde değerlendirilmiştir. Tefsir, hadis ve siyer kaynaklarında ele alınan bazı tarihi hadiselerin karşılaştırmalı bir yöntemle ele alındığı bu çalışma, üç ilim arasındaki irtibatın boyutunu göstermesi bakımından önem arz etmektedir. Hedefi ise bu alanlarda yapılan araştırmalarda disiplinler arası yöntemin önemine dikkat çekmektir. Nitekim araştırmada elde edilen sonuca göre tarihi süreçte bu disiplinlerin meseleyi büyük oranda kendi perspektiflerinden ve kendi alanındaki kaynakları esas alarak değerlendirdikleri görülmüştür. Dolayısıyla bu alanlarda disiplinler arası çalışmalar gereklilik arz etmektedir.
Analysis of Particulate Matter Fraction in Residential Area of Lahore, Pakistan
Authors: Bukhari Syed Shaid Imran , Naeem Aliza , Mughal Samia
Published: April 2024

Background: Air pollution have reached to an alarming level from the past few decades in Pakistan. An increasing trend in particulate matter (PM) pollution in the urban areas have been observed contributing to different health concerns to human like cardiovascular arrest, blood pressure, asthma, pulmonary dysfunction, many eye problems such as cataracts.
Materials and Methods: To analyze the levels of air quality index in the urban areas at a residential site, in Pakistan, PM fractions PM10, PM2.5and PM1.0 were analyzed from 1st October 2022 to 31st March 2023 in provincial capital city Lahore by using a PurpleAir sensor located at Gulberg Town Lahore.
Results: The average PM10 concentration of PM sustained at 200.96 µg/m3 ±138.37 µg/m3 for 6 months with maximum level in December 2022 (851.64 µg/m3 ± 160.58 µg/m3) with an average value of 287.96 µg/m3, and minimum level in March 2023 (10.12 µg/m3 ± 10.10 µg/m3) with an average 30.56 µg/m3. The average PM2.5 concentrations was recorded to 164.59 µg/m3 ± 110.16 µg/m3. for 6 months with maximum level in December 2022 (622.28 µg/m3± 119.06 µg/m3) with an average value of 229.93 µg/m3 and minimum level in March 2023 (9.16 µg/m3 ± 7.94 µg/m3) with an average of 25.24 µg/m3. The average PM1.0 concentration was recorded to 86.19 µg/m3± 51.50 µg/m3 for 6 months with maximum level in November 2022 (252.42 µg/m3 ± 47.54 µg/m3) with an average of 147.94 µg/m3 ± 47.54 µg/m3 and minimum level in March 2023 (5.89 µg/m3 ± 5.15 µg/m3) with an average value 15.89 µg/m3.
Conclusion: Taken into consideration these findings it can be concluded that the high PM levels during November and December were due to the environmental factors including smog, burning of residual crops, brick kilns and excessive vehicle emission.
Dimensiones del significado. Una introducción a la semántica formal
Authors: Verdecchia Matías
Published: April 2024

En la presente reseña, se ofrece al lector un breve recorrido por los contenidos centrales de cada capítulo del manual Dimensiones del significado, al tiempo que se destacan críticamente los aspectos más relevantes de la obra. Respecto a esta última cuestión, la reseña subraya una serie de puntos positivos de libro, a saber, la claridad expositiva, la inclusión de numerosos ejercicios con sus respectivas soluciones, el tratamiento de datos y fenómenos del español y la presentación de la noción de dimensión del significado, tópico ausente en otros manuales de semántica formal.
Academic Augmentation: Analyzing Avatar Design in Educational Metaverse
Authors: Dhillon Preet Kawal Singh , Tinmaz Hasan
Published: April 2024

The emergence of Metaverse from the realms of science fiction into a tangible reality marks a transformative epoch in the digital landscape. Avatars, serving as digital embodiments of users, wield significant influence over educational interactions within this burgeoning virtual realm. This qualitative study embarks on an exploration of how avatar design shapes the landscape of virtual education within the nascent Metaverse. Structured interviews were conducted with a diverse cohort of 20 participants, comprising equal representation of 10 males and 10 females from varied educational backgrounds. Through these interviews, the research utilized qualitative analysis methods (namely as thematic coding) and delved into the nuanced perspectives of participants regarding the impact of avatar design on their learning experiences. Findings unveil the multifaceted role of avatars in online interactions, with attributes such as gender, facial features, and attire emerging as pivotal design elements. Participants' individual personalities and external influences wielded significant sway over their avatar choices, while varying emotional connections translated into preferences for either professional demeanor or self-expression within the virtual educational landscape. Amidst mixed opinions surrounding the educational efficacy of avatar design, some participants foresee heightened engagement, while others express skepticism. Despite acknowledging the socialization benefits, lingering uncertainties persist regarding the Metaverse's efficacy as an educational tool. Preferences regarding avatar promotion and customization exhibit variance, with prevalent concerns revolving around privacy and data security. Furthermore, the comprehensive data analysis of participants' demographics revealed a diverse cohort, encompassing individuals from various countries, academic disciplines, and scholastic years. This multifaceted approach facilitated a comprehensive exploration of avatar preferences and user experiences, enriching the study's findings and enhancing its applicability across diverse educational contexts.
Classification of Diabetes Mellitus Sufferers Eating Patterns Using K-Nearest Neighbors, Naïve Bayes and Decission Tree
Authors: Lubis Ayuni Fachrunisa , Haq Hilmi Zalnel , Lestari Indah , Iltizam Muhammad , Samae Nitasnim , Rofiqi Muhammad Aufi , Abdurrahman Sakhi Hasan , Tambusai Balqis Hamasatiy , Salsilah Puja Khalwa
Published: April 2024

The study investigates three classification algorithms, namely K-Nearest Neighbor (K-NN), Naïve Bayes, and Decision Tree, for the classification of Diabetes Mellitus using a dataset from Kaggle. K-NN relies on distance calculations between test and training data, using the Euclidean distance formula. The choice of k, representing the nearest neighbor, significantly influences K-NN's effectiveness. Naïve Bayes, a probabilistic method, predicts class probabilities based on past events, and it employs the Gaussian distribution method for continuous data. Decision Trees, form prediction models with easily implementable rules. Data collection involves obtaining a Diabetes Mellitus dataset with eight attributes. Data preprocessing includes cleaning and normalization to minimize inconsistencies and incomplete data. The classification algorithms are applied using the Rapidminer tool, and the results are compared for accuracy. Naïve Bayes yields 77.34% accuracy, K-NN performance depends on the chosen k value, and Decision Trees generate rules for classification. The study provides insights into the strengths and weaknesses of each algorithm for diabetes classification
Performance Comparison of Random Forest, Support Vector Machine and Neural Network in Health Classification of Stroke Patients
Authors: Sari Windy Junita , Melyani Nasya Amirah , Arrazak Fadlan , Anahar Muhammad Asyraf Bin , Addini Ezza , Al-Sawaff Zaid Husham , Manickam Selvakumar
Published: April 2024

Stroke is the second most common cause of death globally, making up about 11% of all deaths from health-related deaths each year, the condition varies from mild to severe, with the potential for permanent or temporary damage, caused by non-traumatic cerebral circulatory disorders. This research began with data understanding through the acquisition of a stroke patient health dataset from Kaggle, consisting of 5110 records. The pre-processing stage involved transforming the data to optimize processing, converting numeric attributes to nominal, and preparing training and test data. The focus then shifted to stroke disease classification using Random Forest, Support Vector Machines, and Neural Networks algorithms. Data processing results from the Kaggle dataset showed high performance, with Random Forest achieving 98.58% accuracy, SVM 94.11%, and Neural Network 95.72%. Although SVM has the highest recall (99.41%), while Random Forest and ANN have high but slightly lower recall rates, 98.58% and 95.72% respectively. Model selection depends on the needs of the application, either focusing on precision, recall, or a balance of both. This research contributes to further understanding of stroke diagnosis and introduces new potential for classifying the disease.
EARLY NEOPROTEROZOIC GRANITOIDS IN THE RYAZANOVSKY MASSIF OF THE YENISEI RIDGE AS INDICATORS OF THE GRENVILLE OROGENY AT THE WESTERN MARGIN OF THE SIBERIAN CRATON
Authors: Nozhkin A. D. , Turkina O. M. , Likhanov I. I. , Ronkin Yu. L.
Published: April 2024

Studies of the geological history of the Yenisei Ridge are important not only for understanding the tectonic evolution of mobile belts at the boundaries of ancient cratons but also for problem solving whether the Siberian craton was a part of the Rodinia supercontinent. The mineralogical-petrological, geochemical and isotope-geochronological studies yielded new data on the petrogeochemical composition, petrogenesis features, U-Pb age of zircon, and Sr and 147Sm-143Nd isotopic parameters for the rocks of the Ryazanovsky granitoid massif located near the Yenisei fault zone of the Yenisei Ridge. These rocks are represented by high-ferruginous peraluminous varieties and are comparable to A-granites or highly differentiated I-granites. Their composition evolves from normal to subalkaline granites and leucogranites, characterized by increased concentrations of highly charged and radioactive elements. Isotopic (Sr, Nd) characteristics of the rocks indicate generation from an ancient crustal substrate, the average age of which corresponds to the Paleoproterozoic. The formation of these granites at the Meso-Neoproterozoic boundary (1013±9.9 Ma) corresponds to the early stage of the Grenville orogeny and the formation time of the structure of the Rodinia supercontinent. This episode of regional crustal evolution is correlated with the synchronous successions and similar style of tectonothermal events on the periphery of large Precambrian cratons (Laurentia and Baltica), thus confirming the reliability of the proposed paleocontinental reconstructions of incorporation of the Siberian craton into the Rodinia.
TWO PULSES OF MAGMATIC ACTIVITY DURING THE EARLY RIPHEAN KUONAMKA IGNEOUS PROVINCE FORMATION: PALEOMAGNETIC SUBSTANTIATION OF THE HYPOTHESIS
Authors: Pasenko A. M. , Fedyukin I. V. , Pavlov V. E.
Published: April 2024

By the beginning of the 20th century, at least ten different generations of intrusive mafic bodies 1800–900 Ma were distinguished on the territory of the Anabar massif. The first modern age estimates, however, indicate the formation of the bulk of these bodies in a relatively short period of time ~1480–1500 Ma. Based on geochronological and paleomagnetic data, intrusive bodies with this age were combined into the Kuonamka large igneous province (LIP). However, a complex of paleomagnetic studies indicated the probable existence of at least two pulses of magmatic activity during the formation of this province, differing in age, possibly by ~20 Ma. We performed a paleomagnetic study of subvolcanic bodies of the main composition of Permo-Triassic (dykes) and Mesoproterozoic (sills) age, emerging to the surface in the valley of the middle reaches of the Kotui River. As expected, the studied dikes contain an ancient magnetization, the direction of which is typical for Permo-Triassic magmatic bodies of the region and the Siberian platform as a whole, and the paleomagnetic directions of the sills are close to those previously determined in the age-related subvolcanic bodies of the Kuonamka igneous province (1501±3 Ma) of the Anabar massif. The data obtained allow us to test the previously proposed hypothesis about the existence of two magmatic pulses ~1480 and 1500 Ma ago during the formation of the Kuonamka igneous province. The results of the analysis of already known and new paleomagnetic data obtained by us do not support this hypothesis. A refined paleomagnetic pole was proposed for the Siberian platform ~1500 Ma ago with coordinates 22.6° S, 65.0° E and A95=4.3°.
MINERALOGY AND ZIRCON AGE OF CARBONATITES OF THE SREDNYAYA ZIMA COMPLEX (EASTERN SAYAN)
Authors: Prokopyev I. R. , Doroshkevich A. G. , Varchenko M. D. , Semenova D. V. , Izbrodin I. A. , Kruk M. N.
Published: April 2024

The Srednyaya Zima alkaline-ultramafic carbonatite complex is located in the Eastern Sayan and is a part of the area of manifestation of Neoproterozoic rare-metal alkaline-carbonatite magmatism along the southern and southeastern margins of the Siberian craton. Mineralogical studies of calciocarbonatites of the Srednyaya Zima complex have shown the presence of primary magmatic mineral phases of calcite, biotite (annite-phlogopite), ilmenite, and fluorapatite. Pyrochlore, zircon, burbankite, magnetite, rutile, titanite, strontianite, and barite were identified of the accessory minerals. The chemical composition of the magmatic minerals of the Srednyaya Zima carbonatites is similar to the mineral composition of the closely aged carbonatite complexes Belaya Zima and Arbarastakh. The rare-element and structural analysis of zircon from carbonatites showed the presence of two zones – a magmatic core and areas of recrystallization. U-Pb dating of igneous zircon showed the age interval of its crystallization – 637±4 Ma, which coincides with the geochronology of the formation of alkali-ultramafic rare-metal complexes along the southern margin of the Siberian craton. The formation of Neoproterozoic alkaline-carbonatite complexes is associated with tectonic events of the breakup of the Rodinia supercontinent.
GEOCRYOLOGICAL CONDITIONS OF THE FORMATION OF GIANT SPRING AUFEIS AT THE ANMANGYNDA RIVER (MAGADAN REGION) ACCORDING TO GEOPHYSICAL DATA
Authors: Olenchenko V. V. , Makarieva O. M. , Zemlianskova A. A. , Ostashov A. A. , Kalganov A. S. , Chekryzhov A. V.
Published: April 2024

Giant aufeis fields, common in the Northeast of Russia, are the indicators of water exchange processes in cryosphere. The development of ideas about icing processes is relevant both from the fundamental point of view of studying the permafrost evolution, and from the practical point of view – for the development of aufeis hazard measures. The aufeis in the Anmangynda River basin (aufeis glade area 7 km2) is considered representative of the region, and its studies have been carried out since 1962. In 2022, during the period of maximum thawing of the active layer Electrical Resistivity Tomography (ERT) soundings were carried out at the aufeis glade aiming to identify underchannel taliks and flooded fault zones in bedrock, including local areas of groundwater discharge. It was found that within the main river channels there are underchannel taliks up to 30 m deep. According to the results of 2D inversion, local anomalies of low electrical resistivity mark groundwater filtration channels. In 3D geoelectrical models, pipe-like anomalies of low resistivity are identified in the areas of groundwater discharge, interpreted as filtration channels in the alluvium and the zone of exogenous fracturing in bedrock formed by sandy-clay shales, as well as linear vertical anomalies of low resistivity, interpreted as faults. On vertical sections of 3D resistive models, a connection between faults and filtration channels in alluvium and a layer of exogenous fracturing is traced. In the right bank of the valley, geoelectric signs of taliks in the bedrock, presumably associated with fault tectonics, have been established. It is assumed that the identified faults are the additional transit routes for groundwater in the Anmangynda River valley, along with the alluvial aquifer and the zone of exogenous fracturing of bedrock.
BOUNDARY BETWEEN THE TIMANIAN AND URALIAN TECTONIC CYCLES: RESULTS OF DATING OF DETRITAL ZIRCONS FROM BASAL HORIZONS OF THE LOWER PALEOZOIC SYNRIFT COMPLEX OF THE POLAR URALS, AND IGNEOUS ROCK AGE DATA REPORT
Authors: Soboleva A. A. , Nikulova N. Yu. , Khubanov V. B.
Published: April 2024

The Upper Cambrian-Lower Ordovician terrigenous strata, unconformably overlying the Upper Riphean-Vendian rocks of the Timanide orogen in the north of the Urals, and contemporaneous bimodal volcanics and intrusive rocks are considered complexes marking the beginning of rifting which led to the opening of the Paleo-Ural Ocean later on. The article presents the results of U-Pb (LA-ICP-MS) dating of detrital zircons from sandstones lying at the base of the section of the rift complex in the Malaya Usa River basin in the Polar Urals. It was found that the clastic sequence (identified as the Khoydyshor formation) began to accumulate no earlier than the Cambrian–Ordovician transition. Zircon ages fall within the continuous Vendian to Early Ordovician (575–478 Ma) interval with peak at 512 Ma. This age range overlaps with the age of rhyolites interlayered conformably with sandstones and rhyolite porphyry dikes intruding the Khoydyshor formation, thus indicating a possible admixture of products of synsedimentary volcanism. A narrow zircon age pattern allows us to conclude that the main sources of detrital zircons in sandstones were the Early-Middle Cambrian igneous rocks formed at the stage of pre-rift uplift, and, to a lesser extent, the Late Cambrian-Early Ordovician riftogenic magmatic complexes, marking the beginning of the Uralian tectonic cycle, as well as the Late Vendian igneous rocks of the underlying Timanide orogen. Judging by the Th/U ratio, most of the detrital zircons within the sandstones were derived from the Early Paleozoic silicic volcanic and hypabyssal rocks and the Vendian granitoids and diorites. The almost complete absence of older grains, which are typical of coeval sandstones of the northern part of the Urals, may indicate the accumulation of the considered sandstones in a local trough with local clastic material sources. Probability density estimation of U-Pb ages for zircon from igneous and metamorphic rocks of the Polar Urals indicates that there were no gaps in the Late Riphean to Early Ordovician endogenous activity in this region. The main peaks occur at 552, 521 and 500 Ma, and an additional peak – at 665 Ma. The results of dating of detrital zircons from sandstones of the Khoydyshor formation together with the database of U-Pb isotope ages of igneous and metamorphic rocks of the Polar Urals (119 items), compiled by the authors, indicate that the change in geodynamic regime from collisional orogenesis in the Late Vendian to the Early-Middle Cambrian pre-rift uplift and following Late Cambrian rifting was not accompanied by a longterm discontinuity in magmatic activity.
Assessing Musculoskeletal Disorder Risks in an Automobile Part Manufacturing Factory: A Comparison Study of Biomechanical and Ergonomic Tools
Authors: Eynipour Abouzar , Arjmand Navid , Dianat Iman , Soltanian Ali Reza , Heidarimoghadam Rashid
Published: April 2024

Background: Various tools and methods are available to assess the risk of musculoskeletal injuries in occupational settings, each considering different assessment criteria. While these methods have been previously studied, further comparative investigations are still needed. Objectives: This study aimed to assess the risk of musculoskeletal disorders (MSDs) in workers performing various tasks using different ergonomic and biomechanical risk assessment tools and to compare the outcomes of these tools. Methods: This analytical and cross-sectional study was conducted in a sector of the SAIPA Automobile Part Manufacturing Factory in Iran. A total of 33 workers engaged in lifting, grinding, pushing, and lowering activities participated. Lifting activities involved handling parts weighing 36, 7.9, and 3.4 kg at three workstations. In total, six tasks were examined, and workers' discomfort levels were evaluated using the Cornell Musculoskeletal Discomfort Questionnaires (CMDQ). Fourteen biomechanical and ergonomic risk assessment tools were utilized and compared. Kendall's tau-b correlation coefficient and Cohen's kappa agreement coefficient were applied to determine relationships between different tools and to match the measurement of risk levels, respectively. Additionally, the mean and standard deviation of the data were calculated. Results: There was a high positive correlation between the outcomes of three biomechanical tools [3D static strength prediction programTM (3DSSPP), hand-calculation back compressive force (HCBCF), and JACK], with 3DSSPP and HCBCF being interchangeable for estimating lumbar spine loads. Ergonomic assessment tools showed a suitable correlation in assessing load-carrying tasks. Manual handling assessment charts (MAC) had perfect agreement with National Institute for Occupational Safety and Health (NIOSH), and SNOOK with Washington Industrial Safety and Health Act (WISHA). Among body posture evaluation methods, rapid upper limb assessment (RULA) and rapid entire body assessment (REBA) had the highest correlation. Lifting fatigue failure tool (LiFFT) correlated well with manual handling methods, and survival chance correlated better with body posture evaluation methods. Lowering activities were identified as the most hazardous. Conclusions: Ease of use and accuracy are key considerations when selecting biomechanical risk assessment tools. Experienced assessors can effectively utilize JACK, 3DSSPP, and HCBCF. The MAC and NIOSH, as well as RULA and REBA tools, are interchangeable. Selecting appropriate tools requires consideration of their limitations and advantages.
Pediatric Idiopathic Intracranial Hypertension: Clinical Presentations, Risk Factors, and Prognostic Indicator
Authors: Jafari Narjes , Shahbodagh Khan Golazin , Hassani Amir Hossein , Nikoohemmat Mohammad
Published: April 2024

Background: Idiopathic intracranial hypertension (IIH) is characterized by elevated cerebrospinal fluid pressure without space-occupying lesions, infections, or alterations in brain parenchyma. Diagnosing IIH in children poses a significant challenge for pediatricians, given the often nonspecific nature of clinical signs and symptoms. Objectives: Our study aims to evaluate the clinical presentations and potential risk factors among pediatric individuals diagnosed with IIH, considering the limited research in this particular domain. Methods: Clinical data from pediatric patients diagnosed with IIH who sought care at Tehran's primary referral children's hospitals were collected from 2013 to 2021, spanning eight years. These patients were subsequently contacted to follow up on the presence of persistent headaches and visual problems. Detailed records of their initial signs and symptoms were documented. To identify prognostic factors associated with persistent headaches and visual problems in pediatric IIH patients, binary logistic regression analysis was conducted. Results: A total of 81 pediatric patients were included in the study, with a mean age of 13.56 ± 4.404 years at the time of their IIH diagnosis. The most frequently reported clinical symptom among these patients was headache, observed in 85.2% of cases, followed by diplopia (50.6%), visual impairment (46.9%), and nausea with/without vomiting (44.4%). Furthermore, a substantial proportion of the patients were underweight (weight percentiles < 3). Our analysis showed that male patients and those without strabismus experienced significantly more recurrent episodes of IIH (P = 0.013 and P = 0.013, respectively). Notably, recurrent episodes and higher weight percentiles emerged as predictive factors for future persistent visual problems within our study population (P = 0.032 and P = 0.045, respectively). Conclusions: Recurrence of IIH was significantly less in female patients and those with strabismus. Additionally, we found that both lower and higher weight percentiles, as well as the occurrence of recurrent episodes, served as predictive factors for the development of persistent visual problems. However, our model could not predict persistent headaches.
An Innovative Evaluation of Mass Drug Administration with Primaquine in Iran
Authors: Fekri Jaski Sajjad , Sadeghi Fatemeh , Turki Habibollah , Raeisi Ahmad , Khosravani Mousa , Ghanbarnejad Amin , Ghahremani Zerafat , Hosseini Baharolsadat , Cheshmpoushan Abdolrahim , Azadikhah Hajar
Published: April 2024

Background: A key strategy in the global fight against malaria, endorsed by the World Health Organization (WHO), is mass drug administration (MDA). Evaluating the impact of this initiative on malaria transmission reduction is crucial. Objectives: This study aimed to assess the effectiveness of MDA combined with primaquine (PQ) in the southern Iranian region of Jask, specifically in Lirdaf. Methods: Primaquine was chosen as the antimalarial drug for this intervention. A total of 168 Pakistani individuals receiving MDA were evaluated over an eight-week period from September to December 2021. Results: Three cases of vivax malaria were identified. Among the 168 patients receiving PQ, 26 were found to have a deficiency in the enzyme glucose-6-phosphate dehydrogenase (G6PD), leading to the exclusion of thirty participants from the trial. Additionally, three individuals were withdrawn from the project due to restricted access (two cases) and family-related issues (one case). One participant, initially asymptomatic and positive, later tested positive again, and this case was excluded from the analysis. Regular follow-up assessments were conducted on all participants, revealing no cases of relapse throughout the project duration. Conclusions: Our findings suggest that employing MDA in combination with supplementary interventions during the elimination phase holds promise for malaria control efforts.
Associations Between Fusobacterium nucleatum and msh2, mlh1, and msh6 Gene Expression in Colorectal Cancer
Authors: Torkashvand Reza , Hajikhani Bahareh , Hosseini Doust Reza , Dabiri Hossein , Dadashi Masoud
Published: April 2024

Background: Colorectal cancer (CRC) is a major global health concern, and the link with Fusobacterium nucleatum has received considerable attention. Objectives: This study aimed to explore the prevalence of F. nucleatum and to assess the expression of the msh2, mlh1, and msh6 genes in CRC patients compared to a control group using real-time PCR. Methods: Forty CRC patients and twenty individuals from a control group participated in this study. Gastroenterologists collected biopsy specimens from which DNA and RNA were extracted using a specialized tissue extraction kit. Complementary DNA (cDNA) was then synthesized. Real-time PCR was employed to evaluate the expression levels of the msh2, mlh1, and msh6 genes and the presence of the F. nucleatum-specific 16srRNA gene to determine the relative prevalence of this bacterium in each group. Results: Results indicated a higher prevalence of the F. nucleatum-specific 16srRNA gene in CRC patients than in the control group. Additionally, expression levels of the msh2, mlh1, and msh6 genes were significantly higher in the cancer group, suggesting their role in CRC pathogenesis. The distribution of F. nucleatum was particularly high in the sigmoid and rectum areas of the colon. Conclusions: This study underscores the significance of F. nucleatum in CRC and provides insights into its association with altered gene expression patterns. Understanding the prevalence of F. nucleatum and its impact on msh2, mlh1, and msh6 genes may aid in developing improved diagnostic and therapeutic strategies for CRC. Further research is necessary to elucidate these relationships more comprehensively.
Evaluation of Integrated SARS-CoV-2 Genome Presence in PBMC, Oropharyngeal, and Nasopharyngeal Samples of COVID-19 Patients
Authors: Khanaliha Khadijeh , Donyavi Tahereh , Monavari Seyed Hamidreza , Khatami AliReza , Sadri Nahand Javid , Kiani Seyed Jalal , Tavakoli Ahmad , Ramshyny Mahdi , Bokharaei-Salim Farah
Published: April 2024

Background: Persistent detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in individuals who have recovered from coronavirus disease 2019 (COVID-19) remains an unexplained phenomenon warranting further study. Recent research suggests that this RNA could be the result of transcription from an integrated SARS-CoV-2 genome. Objectives: This study aimed to investigate the presence of the DNA form of the SARS-CoV-2 genome in oropharyngeal, nasopharyngeal, and peripheral blood mononuclear cell (PBMC) samples from COVID-19 patients with prolonged viral detection. Methods: We examined the presence of the reverse-transcribed viral genome in samples from eighty COVID-19 patients, including 40 outpatients (group 1), 40 hospitalized patients (group 2), and 40 healthy individuals (group 3), using a TaqMan® based real-time RT-PCR assay. Results: The mean ages of groups 1, 2, and 3 were 36.1 ± 11.0, 61.6 ± 18.4, and 39.0 ± 8.7, respectively. The molecular tests did not detect viral DNA forms, which may be produced during the SARS-CoV-2 life cycle, in the examined samples. Conclusions: Although no evidence of integrated viral DNA was found in this study, further research is essential to confirm these findings and explore the underlying mechanisms of prolonged SARS-CoV-2 RNA presence in recovered COVID-19 patients.
The originality of the genre of the Dagestan historical novel
Authors: Рамазанова П.К.
Published: April 2024

в статье дается характеристика такого жанра, как исторический роман на примере дагестанской литературы. Автор подробно рассматривает специфику признаков исторического романа на примере таких произведений, как роман М.Хуршилова «Сулак-свидетель», А.Абу-Бакара «Манана» и К.Меджидова «Сердце, оставленное в горах». Указываются временные и пространственные границы произведений. Отмечается документальная основа романов, при этом во всех трех произведениях присутствует и художественный вымысел. Поднимаются как общественные, так и нравственные, социальные проблемы. В романе «Сулак-свидетель» М. Хуршилова и романе «Манана» А.Абу-Бакара главные герои – вымышленные. Но во второй книге «Мананы» есть много и исторических лиц. В романе К.Меджидова «Сердце, оставленное в горах» главный герой – это реальное историческое лицо. Доктор Ефимов, приехавший в дагестанский аул и посвятивший всю свою жизнь дагестанскому народу. Но при этом в произведении не рисуются переломные события, акцент делается на изменении сознания горского народа. Характеризуя классовую борьбу, писатели прибегают к приему антитезы. В статье характеризуется творческое своеобразие каждого из произведений, творческий метод каждого писателя.

the article describes such a genre as a historical novel on the example of Dagestan literature. The author examines in detail the specifics of the features of the historical novel on the example of such works as the novel by M. Khurshilov "Sulak the Witness", A.Abu-Bakar "Manana" and K.Medzhidov "The Heart left in the Mountains". The time and spatial boundaries of the works are indicated. The documentary basis of the novels is noted, while fiction is also present in all three works. Both social and moral, social problems are being raised. In the novel "Sulak the Witness" by M.Khurshilov and the novel "Manana" by A.Abu-Bakar, the main characters are fictional. But there are many historical figures in the second book of Manana. In K.Medzhidov's novel "The Heart left in the Mountains", the main character is a real historical person. Dr. Efimov, who came to Dagestan village and devoted his whole life to the Dagestan people. But at the same time, the work does not depict turning points, the emphasis is on changing the consciousness of the mountain people. In characterizing the class struggle, writers resort to the antithesis technique. The article characterizes the creative originality of each of the works, the creative method of each writer.
Cognitive foundations for the study of linguistic units with the meaning ENRICHMENT
Authors: Мирошниченко Н.С. , Раздабарина Ю.А. , Страхова К.А.
Published: April 2024

в статье рассматриваются значения лексемы ОБОГАЩЕНИЕ, а так же изучается использование концепта ОБОГАЩЕНИЕ в различных отраслях сферы деятельности человека, а именно носителя британского английского языка, на основе языкового материала, взятого на сайте языковой базы данных British National Corpus. Выбор материала обусловлен полнотой данной базы и ее актуальностью. Целью проведенного корпусного исследования является раскрытие специфики репрезентации языковых единиц со значением ОБОГАЩЕНИЕ в англоязычной картине мира. Была поставлена задача рассмотреть когнитивное основание для исследования данных лексических единиц. В статье обозначены концептуальные области их употребления и значения, которые эти лексические единицы передают в данных контекстах. Научная новизна исследования проявляется в проведении когнитивного анализа словарных толкований глаголов, которые были выявлены в процессе изучения лингвистического материала, используемых в передаче смысла понятия ОБОГАЩЕНИЕ в письменной и устной речи. В результате исследования были определены концептуальные области, в которых чаще всего используются данные языковые единицы. Так же исследование показало, что концепт ОБОГАЩЕНИЕ может характеризоваться не только положительной, но и отрицательной коннотацией. Практическая значимость заключается в возможности использования результатов данной работы на занятиях по лексикологии английского языка и в спецкурсах по лингвоконцептологии.

the article examines the meanings of the lexeme ENRICHMENT, and also studies the use of the concept ENRICHMENT in various branches of human activity, namely, native speakers of British English, based on language material taken from the website of the British National Corpus language database. The choice of material is determined by the completeness of this database and its relevance. The purpose of the conducted corpus research is to reveal the specifics of the representation of linguistic units with the meaning ENRICHMENT in the English-language picture of the world. To achieve this goal, the task was set to consider the cognitive basis for the study of these lexical units. The article outlines the conceptual areas of their use and the meanings that these lexical units convey in these contexts. The scientific novelty of the study is manifested in the cognitive analysis of dictionary interpretations of verbs that were identified in the process of studying linguistic material used in conveying the meaning of the concept ENRICHMENT in written and oral speech. As a result of the study, the conceptual areas in which these linguistic units are most often used were identified. The study also showed that the concept ENRICHMENT can be characterized not only by positive, but also by negative connotations. The practical significance lies in the possibility of using the results of this work in classes on lexicology of the English language and in special courses on linguoconceptology.
Features of the development of promotional content in Telegram
Authors: Полунина О.С.
Published: April 2024

статья посвящена актуальному вопросу разработки промо-контента для Телеграм-каналов. Исследование является актуальным в силу ряда причин: во-первых, рекламный рынок в Телеграм недостаточно изучен, в силу его взрывного роста в недавнее время, во-вторых, аудитория мессенджера довольно лояльна к рекламным и промо-сообщениям из-за принципиальных отличий мессенджеров от социальных сетей, в-третьих, изменение парадигмы потребительского поведения заставляет нас изучать новые способы подачи и форматы размещения промо-контента, анализировать вовлеченность и эффективность каналов, форматов и подходов. Современный промо-комплекс, направленный на продвижение в Телеграм, включает в себя следующие форматы: текст, фото, видео, графика. Кроме того, по целям можно выделить развлекательный, новостной и полезный типы контента. Все три типа могут успешно решать задачи по продвижению и включать в себя элементы промо. Применение промо-контента в российском сегменте Телеграм является новым направлением в развитии данной сферы, и изучение этого опыта становится перспективной задачей. Практика применения масштабна и разнообразна.

the article is devoted to the topical issue of developing promotional content for Telegram channels. The research is relevant for a number of reasons: firstly, the advertising market in Telegram has not been sufficiently studied, due to its explosive growth in recent times, secondly, the messenger audience is quite loyal to advertising and promotional messages due to the fundamental differences between messengers and social networks, thirdly, a change in the paradigm of consumer behavior forces us to explore new ways of presenting and placing promotional content, analyze the involvement and effectiveness of channels, formats and approaches. The modern promotional complex aimed at promotion in Telegram includes the following formats: text, photos, videos, graphics. In addition, entertainment, news and useful types of content can be distinguished by goals. All three types can successfully solve promotion tasks and include promo elements. The use of promotional content in the Russian segment of Telegram is a new direction in the development of this area, and the study of this experience is becoming a promising task. The practice of application is large-scale and diverse.
Аnalysis of communication strategies of social advertising and characteristics of social projects of Chinese corporations
Authors: Тянь К.
Published: April 2024

как и во всем мире, рост социальной рекламы в Китае объясняется непрерывной урбанизацией и цифровизацией. Однако, по сравнению с другими странами, китайский рынок в значительно большей степени полагается на цифровые варианты рекламных кампаний для привлечения аудитории. С учетом отмеченного, цель статьи заключается в проведении анализа коммуникационных стратегий социальной рекламы и характеристик социальных проектов некоторых китайских корпораций. В процессе исследования рассмотрены такие стратегии как маркетинг влияния, конкурсы и пользовательский контент, прямые трансляции, использование привлекательных визуальных эффектов и видеороликов. Полученные результаты свидетельствуют о том, что компании для привлечения аудитории в социальных сетях используют комбинацию различных стратегий, в зависимости от задач маркетинговых коммуникаций и целевой аудитории.

the world of social media is constantly evolving. The Chinese digital market is based on the multifaceted potential of unique media platforms with more than half a billion followers and 100 million posts per day. However, the Chinese social media landscape has its own distinctive features, which predetermines the specificity of communication strategies. With this in mind, the purpose of this article is to analyze the communication strategies of social advertising and the characteristics of Chinese corporations' social projects. In the process of the research such strategies as influencer marketing, contests and user-generated content, live broadcasts, use of attractive visual effects and videos are considered. The results show that companies use a combination of different strategies to attract audiences in social networks depending on the objectives of marketing communications and the target audience. Studying the experience of a number of Chinese companies in promoting social advertising allows us to conclude that it is effective in terms of saving advertising budgets, increasing brand awareness and reaching more users.
Realization of intertextuality in media-political discourse (based on the speeches of President Xi Jinping)
Authors: Хань Х.
Published: April 2024

в условиях углубления межкультурной коммуникации изучение интертекстуальности имеет большое практическое значение, поскольку культурные контексты формируются в уникальных социальных условиях и не могут быть обобщены, важно учитывать не только ситуационный, но и культурный контекст коммуниканта. Медиа- политический дискурс не только служит для передачи важных сообщений, но и несет дипломатическую ответственность. Выступления лидеров страны во многом определяют направление развития государства. Интертекстуальность как риторический прием обогащает экспрессивные стратегии медиа-политического дискурса, не только отражает многовековую историю страны и распространяет ее прекрасную культуру за рубежом, но и углубляет взаимопонимание между странами, что имеет важную социальную ценность и практическую значимость. В данной статье автор анализирует интертекстуальность в речи председателя КНР Си Цзиньпина и обобщает три наиболее часто встречающиеся формы интертекстуальности в речи: цитирование, аппликация, аллюзия, чтобы изучить прагматические особенности интертекстуальности.

in the context of deepening intercultural communication, the study of intertextuality is of great practical importance, since cultural contexts are formed in unique social conditions and cannot be generalized, it is important to take into account not only the situational but also the cultural context of the communicator. Media political discourse not only serves to convey important messages but also has diplomatic responsibilities. The speeches of the country's leaders largely determine the direction of the state's development. Intertextuality as a rhetorical device enriches the expressive strategies of media-political discourse, not only reflects the country's centuries-old history and spreads its beautiful culture abroad, but also deepens mutual understanding between countries, which has an important social value and practical significance. In this paper, the author analyzes intertextuality in the speech of Chinese President Xi Jinping and summarizes the three most common forms of intertextuality in speech: quotation, application, allusion, in order to explore the pragmatic features of intertextuality.