bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of knowledge, attitude, and practices of health care waste management among nurses in Nyambene Level 4 hospital
Authors: Nyabaro Pius , Shitemi Faustina , Keter Moses , Kaimuri MaryJoy
Published: December 2022

Healthcare waste management requires an organized, systematic channeling of waste, consistent with acceptable public health and environmental safeguards (Vanesh et al., 2019). The Ministry of Health estimates that 47% of hospital waste generated cannot be accounted for (Hugo & Lima, 2021). This indicates improper segregation, thus putting health care workers, the population, and the general environment at risk. The broad objective was to assess nurses' knowledge, attitude, and practices in healthcare waste management at Nyambene Level 4 Hospital. The study adopted a cross-sectional design. The target population of this study was nurses working in Nyambene level 4 Hospital with a sample size of 61 nurses. The data collection tool was the questionnaire. The study findings showed that 93.4% (57) of the nurses had good knowledge of waste management, 52.46% (32) of the nurses had a positive attitude and majority (55.7% (34) of the nurses had average waste management practices. Generally, the nurses had good knowledge of waste management. Most nurses had a positive attitude towards prioritizing waste disposal, among other activities in the hospital, and the nurse's practice was generally average. The researchers recommended regular training and education for the nurses, awarding certificates and tokens to nurses who show proper waste management and the administration to carry out regular health care waste management inspections. For example, ensuring each department has three waste management bins. In addition, the researchers recommended introduction of an infection control program to prevent and stop transmission of infections due to improper waste management.
SMEs and Covid-19. The aftermath:
Authors: Gatobu Rintaugu
Published: December 2022

The Corona-Virus (Covid-19) has had ruthless ramifications on all businesses (Small and Large) since its emergence in 2019/2020. It has devastated jobs and businesses across the globe. SMEs have had the worst experiences caused by this crisis, such as loss of revenue owing to disruptions in organizational structures, supply chains and huge losses as a result. This paper looks at how SMEs have engaged during the period of Covid-19 and the period thereafter. The study is conducted in the context of Kenyan SMEs using a sample of 500 SMEs from both manufacturing and services sectors.

The results indicate that SMEs are now more aware of its effects and relevance to their performance, survival and growth, hence the need for them to focus on innovative ways of cultivating sustainability, way beyond the pandemic.
Relationship Of Motivation And Performance Of Integrated Healthcare Center Cadres During The Covid-19 Pandemic On Basic Immunization Coverage In 2020 In The Working Area Of Bojongsari Public Health Center
Authors: Ilmi Ayatun Fiil , Adhana Shelvia , Holidah Holidah , Ratnaningtyas Tri Okta
Published: December 2022

Abstrak                                                        

Imunisasi dasar adalah imunisasi wajib yang ada didalam program Puskesmas dimana semua bayi yang berusia di atas 12 bulan harus sudah mendapatkan imunisasi dasar. Karena imunisasi dasar dibuat menjadi program agar penyakit yang ada tersebut dapat dicegah dengan imunisasi. Imunisasi yang ada didalam program Puskesmas mempunyai tujuan melindungi anak dari penyakit, mencegah kecacatan pada anak, juga untuk mencegah kematian pada anak. Di Indonesia Cakupan Imunisasi Dasar Lengkap (IDL) mengalami penurunan mencapai 57,9%, imunisasi tidak lengkap sebesar 32,9% dan 9,2% tidak diimunisasi. Presentasi tertinggi terdapat di Bali (92,1%) dan yang terendah di Aceh (19,5%). (Kemenkes 2018). Tujuan penelitian ini adalah untuk mengetahui hubungan antara motivasi dan kinerja kader posyandu pada masa pandemi covid-19 terhadap cakupan imunisasi tahun 2020 di Wilayah Kerja Puskesmas Bojongsari. Metode penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan kuantitatif dan desain case control. Teknik pengambilan sampel yang digunakan adalah dengan purposive sampling yang terdiri dari 42 responden kasus dan 42 responden kontrol. Teknik pengumpulan data dengan menggunakan kuesioner langsung. Hasil analisis data pada penelitian ini menggunakan chi-square bahwa hubungan motivasi terhadap cakupan imunisasi didapatkan hasil signifikan p-value = 0,000, dan hubungan kinerja terhadap cakupan imunisasi didapatkan hasil signifikan p-value = 0,000. Kesimpulan: adanya hubungan antara motivasi dan kinerja kader posyandu terhadap cakupan imunisasi. Saran: bagi peneliti selanjutnya diharapkan untuk mengubah cara pengukuran di variabel agar hasil pengukurannya lebih efektif.

 

Kata Kunci: : Motivasi; Kinerja; Cakupan Imunisasi
ARIAS (Assurance, Relevance, Interest, Assessment, and Satisfaction) Learning Model and Learning Interest: How does it affect Critical Thinking?
Authors: Wawan Wawan , Pamungkas Tubagus
Published: December 2022

This study aimed to determine whether 1) ARIAS learning model affected critical thinking skills; 2) students’ learning interest category (high, medium, and low) affected critical thinking skills; and 3) there is an interaction between the learning model groups and the learning interest groups on critical thinking skills. This research was a quasi-experimental research with a 2 X 3 factorial research design. The instruments used to collect the data were a critical thinking test and a learning interest questionnaire. The data analysis technique used in this research was the analysis of the two-way variance of two unequal cell paths. According to the results of research and discussion, it was found that 1) there was an effect of the ARIAS learning model on students’ critical thinking skills; 2) students’ learning interest did not affect their critical thinking skills; 3) there was no interaction between the ARIAS learning model and learning interest on critical thinking skills.
Problem-Based Learning (PBL) Model: How Does It Influence Metacognitive Skills and Independent Learning?
Authors: Saputri Vina Nopia , Kesumawardani Aryani Dwi
Published: December 2022

The problem-based learning (PBL) model creates an active and creative learning atmosphere. It is expected to positively influence students' cognitive skills and learning independence. This research aimed to determine whether the PBL model influence 1) students' metacognitive skills; 2) students' learning independence; and 3) metacognitive skills and learning independence simultaneously. This research was a quasi-experimental research with a Posttest-Only Control Group Design. This research employed the quantitative method with the cluster sampling technique. The instruments of this research were a metacognitive skill description test and a learning independence questionnaire. The research hypothesis was tested using the MANOVA test after the data had been tested for their normality and homogeneity. The results showed that the PBL model influenced 1) students' metacognitive skills; 2) students' learning independence; and 3) metacognitive skills and learning independence simultaneously. The results indicated that the PBL model produced a better result on students’ metacognitive skills and learning independence compared to the conventional learning model.
Difficulty analysis of numerical ability of indigenous Papuans (Marind and Kanum Tribes) in Yanggandur and Wasur Villages, Merauke Regency
Authors: Suhartini Andi Sitti , Widanarti Indah , Nurlaelah Elah , Fatimah Siti
Published: December 2022

Mathematics is one of the subjects that provides the provision of reasoning needed to become a quality human being. Counting is a very small part of mathematics, but it is very important. This study aims to analyze the difficulties in numeracy of the Marind and Kanum tribal communities in Yanggandur and Wasur Villages, Merauke Regency. The methods used are literature study and observation. The results of the study show that the Marind and Kanum tribes have difficulty calculating operations in large numbers because most of the people's daily lives do not use large numbers of addition and subtraction operations, namely hunting and fishing. The community also has staple foods, namely kumbili and sago, which are obtained from their own villages so that there are no transactions that require large amounts of calculation.
Android-Based Digital Book Oriented to Multiple Chemical Representations on Terpenoid Learning Materials
Authors: Ummah Nur Fadlilah Khoerul , Windayani Neneng , Irwansyah Ferli Septi , Sulaeman Dedi
Published: December 2022

This research aims to describe and analyze the application results of the developed digital book oriented to multiple chemical representations. The method employed in this research was the Design-Based Research (DBR) method with the ADDIE development model. The ADDIE development Model consisted of five stages to analyze, design, and develop a product. These stages covered the analysis of terpenoid material, the analysis of multiple representations of terpenoid material, and digital book design and development. The instrument used was a validation test questionnaire filled out by three validators. The result of this research is an Android-based digital book oriented to chemistry's multiple representations. The obtained robserved value was 0.83. Therefore, the developed digital book was declared valid and can be used as teaching material in the Natural Product Chemistry course.
Decision-making in agribusiness based on artificial intelligence
Authors: Valim Bandeira Marina , De Souza Móta Léia Michele , Behr Ariel
Published: December 2022

Purpose: Artificial Intelligence (AI) tools have become popular in the most diverse contexts of use. This research sought to investigate how AI tools were applied in agribusiness by assisting producers in decision-making.
Design / methodology / approach: To this end, online and semi-structured interviews were conducted with managers and rural producers who use this type of technology on their properties.
Findings: AI was found to be present in machinery, software, and other applications applied for crop monitoring, soil quality verification, and management in general. Users are quite optimistic with the results, especially in decision support during planting period. These differences are perceived before and after technologies utilization. However, interviewers still believe that the human presence is fundamental in the farming.
Research limitations / implications: As limitations, it is highlighted the schedule for conducting the interviews, as well as the fact that they were performed online. Despite this, it was possible to verify the importance of the use of technology for the agribusiness sector, serving as support for the management of rural properties.
Originality / value: In the Information Systems studies field to relate the use of AI and decision-making in a sector such as agribusiness is something recent and innovative.
Prägnanzwahrnehmung bei exemplarischen Leitmotiven des Serienuniversums „CW‘s Arrowverse“ – Zwei kognitionspsychologische Studien
Authors: Ungerer Marietta , Wolf Anna
Published: December 2022

Prägnanz ist eines der grundlegenden Konzepte der Gestaltpsychologie, aber vergleichsweise wenig für den musikalischen Bereich erforscht. Prägnanz wird dabei häufig als übergeordnetes Gestaltgesetz beschrieben, das mehrere Unterkategorien wie zum Beispiel Ordnung aufweist. Die vorliegende Forschungsarbeit hatte daher zum Ziel, den Einfluss von melodischer und rhythmischer Entropie als Ordnungsmaß auf die Prägnanzwahrnehmung von filmmusikalischen Leitmotiven aus dem amerikanischen TV-Serienuniversum „CW‘s Arrowverse“ zu untersuchen. Basierend auf einer explorativen Teilstudie mit musikalischen ExpertInnen (N = 17) wurde eine zweite Online-Studie mit Nicht-ExpertInnen (N = 50) durchgeführt, bei denen die ProbandInnen zehn Leitmotive mit Hilfe von 15 Adjektiven bewerten sollten. Mit jeweils sechs bzw. zehn dieser Adjektive konnten zwei wahrnehmungspsychologische Faktoren für Prägnanz bzw. Entropie der Leitmotive mittels explorativer Faktorenanalysen identifiziert werden. Zwischen diesen Faktoren zeigte sich ein negativer quadratischer Zusammenhang (F (2,7) = 1.12, p = .38), der 24.3% der Varianz aufklärte. Dies stimmt mit bisherigen Erkenntnissen überein und liefert Anregungen für weiterführende Forschung. Während Random-Forest-Modelle in Teilstudie I zunächst noch das melodisch-rhythmische Feature „metric_complexity_division“ (0.03) als zentral zur computerbasierten Abbildung von Präganzwahrnehmung identifizierten, konnten die verwendeten Modelle in Teilstudie II keine Ergebnisse generieren. Gründe für die gefunden Schwächen werden diskutiert und liefern wichtige Erkenntnisse auf dem Gebiet der Computational Musicology.
The plight of the ‘asthmatic patient’ in South Africa – a subgroup analysis of the SABINA III study
Authors: Kalla I S
Published: December 2022

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Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome
Authors: Hiesgen J , Annor T N
Published: December 2022

Posterior reversible encephalopathy syndrome (PRES) is an uncommon, subacute neurological disorder that presents radiologically witha pattern of bilateral parieto-occipital areas of vasogenic oedema. Conditions commonly associated with PRES include autoimmunedisorders, cytotoxic drugs, metabolic abnormalities and, most frequently, hypertensive emergencies. Clinically, headache, visualdisturbances, seizures and an altered level of consciousness are often reported. The outcome is favourable if the underlying cause isaddressed. Posterior fossa involvement resulting in obstructive hydrocephalus is a rare presentation and may be misdiagnosed as a mass lesion or infection, leading to delayed or unnecessary treatment. We describe the clinical presentation, findings on neuroimaging and conservative management of a man with PRES resulting in severe cerebellar oedema and acute obstructive hydrocephalus. This case illustrates that awareness of atypical neuroimaging in PRES is important for the management of these patients and to avoid morbidity and mortality.
Discoespondilite em bezerro Red Angus
Authors: Moroz Michail , Medeiros de Liz Bruna , Schade Jackson , Martin Camila Cecilia , Do Amaral Kwirant Liomara Andressa
Published: December 2022

O período neonatal é considerado crítico para o desenvolvimento de um bezerro, tanto pela imatu-ridade do sistema imunológico quanto por condições ambientais insalubres na fase de criação que tornam o animal propenso a infecções. Apesar do período neonatal e a fase de criação apresentarem maior incidência de diarreias, broncopneumonias e onfalopatias, doenças como osteomielite e discoespondilite podem ocasionalmente ocorrer de forma secundária a focos infecciosos. O objetivo do presente trabalho é apresentar um caso de discoes-pondilite em um bezerro de 3 meses de idade, com histórico de pneumonia na primeira semana de vida. Na segunda semana de vida, começou a desenvolver distúrbios de coordenação motora, tetraparesia, dificuldade em elevar cabeça e pescoço, além de inabilidade em levantar e manter-se em estação e sensibilidade dolorosa, principalmente durante a flexão e extensão dos membros anterior e posterior direito. Exames complementares foram realizados: o hemograma revelou leucocitose por neutrofilia; o perfil bioquímico demonstrou hipoproteinemia; a radiografia cervical demonstrou áreas radioluscentes circulares compatíveis com lise óssea, associada à proliferação e áreas marginais de esclerose, concluindo diagnóstico de discoespondilite. O tratamento instituído foi de sulfadoxina com trimetoprim, SID. Em consoante, tratamento fisioterápico com auxílio de talha, caminhadas supervisionadas e massagem com dimetilsulfóxido, BID. Após completa remissão dos sinais clínicos e realização de novo hemograma com resultados dentro da normalidade, o animal retornou à propriedade de origem.
Development of the LISP Interpreter
Authors: Barabash Konstantin Alekseevich , Mangusheva Alina Raisovna , Obukhova Margarita Yur'evna , Grigoryan Karen Al'bertovich
Published: December 2022

The article highlights aspects of the development of the LISP interpreter. Despite the fact that LISP is not the most popular language these days (in the TIOBE index for November 2022, this language is in 30th place), the work done by the authors is relevant. Many popular ideas and software technologies today were first developed using LISP machines. The developed interpreter allows the programmer to avoid defining program elements (functions, classes, etc.) unnecessarily. Also, the development result allows you to run any LISP entity that returns a meaningful result. Modern LISP interpreters do not have the ability to overload functions, which is why users have to memorize a huge number of function names whose actions are of the same type. This greatly complicates the learning process, since you have to look for the names of primitive functions in the documentation. Because of this, most of the potential users drop out of training, returning to modern programming languages, without knowing the possibilities of the LISP language. The article reveals the creation of a LISP interpreter capable of competing with modern programming languages in terms of ease of interaction with objects. The article also suggests an approach that provides a garbage collection mechanism by counting references to objects.
PERCEPCIÓN DE INSEGURIDAD EN EL ESPACIO PÚBLICO DE SANTIAGO EN TIEMPOS DE PANDEMIA
Authors: Fuentes Luis , Rodríguez Sebastián , Señoret Andrés , Figueroa Cristhian
Published: December 2022

La percepción de inseguridad de las mujeres en el espacio público ha aumentado con la pandemia, aumentando la brecha que tienen respecto a los hombres del Gran Santiago. Esto es independiente de la zona de la ciudad y el nivel socioeconómico. Además, en términos de movilidad, las mujeres se sienten más inseguras utilizando el vehículo particular y caminando, superando ampliamente la percepción de los hombres en estos modos.
Development of a Solar Power Generating System with Auto-Tracking and Data Logging Devices
Authors: Onawumi A. S. , Akinrinade N. A. , Olojede M. A. , Ajayeoba A. O.
Published: December 2022

Solar power systems have become a viable wellspring of sustainable energy over the years and are commonly used for a variety of industrial and domestic applications. Capturing and storing the maximum amount of available energy for prediction and future analysis have been the major problems. This study aimed at developing a solar power generating system with solar tracking and data logging devices. The Dual Axes Solar Power Generating System (DASPGS) was developed using a combination of hardware and software systems consisting of three major subsystems: mechanical, electro-mechanical, and electrical tracker parts. C-language programme was used in conjunction with the Arduino Uno board for logging the power generated from the DASPGS and already fabricated Fixed Axis Solar Power Generating System (FASPGS). The power generated was stored on the created web page and the Secure Digital (SD) card. Data were harvested and the performance evaluations of the DASPGS over FASPGS were determined for 28 days. DASPGS gave average power of 22.88, 22.25, 24.49, and 25.92 Watts per week while FASPGS gave 5.16, 15.00, 16.23, and 15.74 Watts per week. A significant difference between DASPGS and FASPGS gave a P value of .004. This study showed that the DASPGS performed better than FASPGS. The system developed finds its application in the area of solar power prediction.
The Effect of SNI 6729 : 2016 on Organic Vegetables Purchase Intention and Purchase Behavior (Case Study : PT Rumah Roti Indonesia)
Authors: Nugroho Imanuella Indah , Fahma Fakhrina , Damayanti Retno Wulan
Published: December 2022

At a time when the people's increasing demand for organic vegetables can be an opportunity for PT Rumah Roti Indonesia to expand its market beyond the scope of PT Rumah Roti Indonesia. Organic certification is one way to expand the market. The aim of this study is analyze the effect of SNI 6729: 2016 certification on purchase intention and purchase behavior of organic vegetables in Indonesia so that PT Rumah Roti can take the right decision. To see the effect of SNI 6729 : 2016, this study uses the Theory of Planned Behavior model. Data processing was used in the PLS-SEM method. The results of this study prove that the variables perceived behavioral control, subjective norms, and perceived quality have a significant effect on purchase intention in organic vegetables and awareness has a significant effect on moderating the relationship between purchase intention and purchase behavior. In addition, it was found that purchase intention has a significant effect on purchase behavior. These results indicate that there is an influence of SNI 6729 : 2016 on purchase intention and purchase behavior of organic vegetables.
Ray Kroc’s Interactional Styles Features in Business Conversation in The Founder
Authors: Pratikno Cindy Melani
Published: December 2022

This study focuses on the features of interactional styles used by Ray Kroc, the male main character, when in a business conversation with others in The Founder biographical movie. The writer used Holmes’ (2006) theory of features of interactional styles and Holmes' (2006), Kuntjara's (2012), and Paltridge's (2006) theory of gender to support her in conducting this research. The writer transcribed and analyzed Ray Kroc's utterances during business conversations with others for this study, which took a qualitative approach. Facilitative, supportive feedback, conciliatory, indirect, collaborative, person/process-oriented, and affectively oriented are all features of feminine interactional styles used by Ray Kroc. He also demonstrated all masculine interactional styles features, including competitive, aggressive interruptions, confrontational, direct, autonomous, task/outcome-oriented, and referentially oriented. The findings of this study support Holmes' (2006) observation that men and women can use both feminine and masculine interactional styles depending on the situation in the workplace. Ray Kroc, a competitive and masculine man, used feminine and masculine interactional styles to keep his relationships with his partners strong and achieve his business conversation goals at the same time. Moreover, further research for the film The Founder or other movie that focuses on other characters, situations, and theories is recommended.
Exploring The Slang Word Formation Processes Found in Girlboss Tv Series
Authors: Partadarsana Areta Tirza , Mardijono Josefa Juniarti
Published: December 2022

The purpose of this study was to investigate the formation of slang words used by Sophia, the main character of the Girlboss TV Series. The writer conducted this study to determine the types of word formations formed in Sophia's slang words in each episode and the morphological processes involved in the creation of those slang words. Additionally, this study was carried out in a qualitative approach. The writer used the theory of word formation and morphology by Yule (2020) in her study. The findings revealed that compounding, blending, clipping, coinage, acronyms, derivation, and multiple processes were all used in the formation of slang words used by the main character in the Girlboss. Meanwhile, borrowing, backformation, hypocorism, and conversion were not found in the data analysed. Based on their respective origin words and the theory of the types of word formation processes, the slang words that appear in these 11 episodes are divided into several different types of word formation. In short, it showed that the main character of Girlboss TV series often uses slang when communicating with their peers, some of which are in the form of abbreviations, modified elements from original words, and some use new words.
The Illocutionary and Perlocutionary Acts Produced by The Main Characters of Moxie Movie
Authors: Susanto Angelina
Published: December 2022

Speech acts are crucial in establishing and achieving a conversation's goal. The purpose of this research is to examine speech acts in the Moxie movie. This study examines types of illocutionary acts and perlocutionary acts produced by the main characters of the Moxie movie, Vivian and Claudia. The writer used two different theories to conduct this research: the theory of speech act by Austin (1962, as cited in Cutting, 2002) and the classification of illocutionary act by Searle (1975, as cited in Cutting, 2002) and Leech (1983, as cited in Peccei, 1999). This study was done using a qualitative approach. The data that the writer used to analyze were Vivian and Claudia’s conversations in the Moxie movie. The results of the data analysis revealed that there were four types of illocutionary acts produced by Vivian: Representative, Expressive, Directive, and Rogative. Meanwhile, Claudia produced five types of illocutionary acts: Representative, Expressive, Directive, Commissive, and Rogative. Also, there were two effects of the perlocutionary acts, whether it is in accordance or not in accordance with the illocutionary act. In conclusion, this study has examined how the main characters of Moxie movie deliver their messages through speech acts.
Prospecção Tecnológica e Científica de Testes Rápidos para Hemoglobina Glicada (HbA1c)
Authors: Farrapo Jéssica Silva Teles , Gris Eliana Fortes , Nascimento Paulo Gustavo Barboni Dantas , Ferreira Eduardo Antonio
Published: December 2022

Hemoglobina glicada (HbA1c) é um biomarcador utilizado no diagnóstico e na avaliação em longo prazo da Diabetes mellitus. Os testes rápidos de dosagem de HbA1c permitem a realização de análises simples e com resultados imediatos, facilitando o atendimento. Este trabalho apresenta um estudo de prospecção baseado no levantamento e na análise de patentes e de artigos científicos sobre testes rápidos de HbA1c. A prospecção tecnológica revelou que China, Estados Unidos e Coreia do Sul lideram o cenário de produção tecnológica, e a empresa norte-americana Polymer Technology Systems lidera o ranking de depósitos. O levantamento de patentes mostrou que há interesse tecnológico atual por esses testes rápidos, justificado pelo aumento de depósitos nos últimos anos, atingindo o pico em 2019. A prospecção científica revela que os Estados Unidos lideram a produção científica e aponta que o foco de mercado desses testes rápidos são laboratórios, consultórios e clínicas, devido à rapidez e à simplicidade analítica.
Da medicalização do parto à violência obstétrica:
Authors: Gomes Bruna Maria Costa , Dos Santos Silva Souza Stephany
Published: December 2022

Resumo: Este artigo possui o objetivo de traçar um percurso histórico sobre como ocorre o processo de medicalização do parto e de que modo ele fornece pano de fundo às práticas de violência, muitas vezes disfarçadas de rotinas, especificamente quando se trata das mulheres negras. Assim, a proposta é compreender a violência obstétrica e de que forma ela se materializa, por meio da medicalização abusiva do parto e se intensifica ‘interseccionada’ às questões de gênero, raça e classe. Para tanto, foram empreendidas pesquisa bibliográfica e documental, a partir de uma abordagem qualitativa. Diante do exposto, observa-se que a medicalização do parto e a violência obstétrica atingem de maneira particular as mulheres negras.
PALAVRAS-CHAVE: Parto. Medicalização. Violência obstétrica. Interseccionalidade.
Antídotos contra o leite ruim
Authors: Oliveira João Manuel
Published: December 2022

Livro resenhado: TRUJILLO, Gracia. El feminismo queer es para todo el mundo. Madrid: Catarata, 2022.
A pandemia da covid-19 e suas repercussões para a educação básica: revisão sistemática da literatura
Authors: Dos Santos Telaska Tatiele , Larissa Machado Adrieli
Published: December 2022

O presente trabalho tem como objetivo investigar as repercussões da pandemia da Covid-19 na educação básica. A metodologia utilizada foi revisão sistemática da literatura, realizou-se a busca por artigos indexados nas bases de dados Scientific Electronic Library Online (SCIELO) e Revistas Científicas de América Latina y el Caribe (REDALYC), com as palavras-chave “Covid-19” e “educação básica”, juntamente com o descritor booleano and. Foram encontrados 10 artigos que atenderam aos critérios de inclusão e exclusão da pesquisa. O público envolvido nas pesquisas encontradas foi na maioria profissionais da educação, professores, diretores, coordenação pedagógica, assistente de secretaria e professoras. Os resultados encontrados apontam que os professores enfrentam dificuldades diante da pandemia da Covid-19, como, falta de apoio familiar na resolução das atividades, adaptação à nova realidade, habilidades tecnológicas e no desenvolvimento de mídias digitais de ensino. Conclui-se que, pesquisas na área devem ser mais aprofundadas e avaliar as repercussões de modo longitudinal.
Cross-Clade Memory Immunity in Adults Following SARS-CoV-1 Infection in 2003
Authors: Ng Rita W. Y. , Boon Siaw S. , Chen Zigui , Ho Wendy C. S. , Fung Kitty S. C. , Wong Barry K. C. , Yeung Apple C. M. , Wong Martin C. S. , Chan Paul K. S.
Published: December 2022

Importance

Knowledge of the longevity and breath of immune response to coronavirus infection is crucial for the development of next-generation vaccines to control the COVID-19 pandemic.

Objectives

To determine the profile of SARS-CoV-2 antibodies among persons infected with the closely related virus, SARS-CoV-1, in 2003 (SARS03 survivors) and to characterize their antibody response soon after the first and second doses of COVID-19 vaccines.

Design, Setting, and Participants

This prospective cohort study examined SARS-CoV-2 antibodies among SARS03 survivors compared with sex- and age-matched infection-naive controls. Participants received the COVID-19 vaccines between March 1 and September 30, 2021.

Interventions

One of the 2 COVID-19 vaccines (inactivated [CoronaVac] or messenger RNA [BNT162b2]) available in Hong Kong. Two doses were given according to the recommended schedule. The vaccine type administered was known to both participants and observers.

Main Outcomes and Measures

SARS-CoV-2 antibodies were measured prevaccination, 7 days after the first dose, and 14 days after the second dose.

Results

Eighteen SARS03 adult survivors (15 women and 3 men; median age, 46.5 [IQR, 40.0-54.3] years) underwent prevaccination serologic examination. The vast majority retained a detectable level of antibodies that cross-reacted with SARS-CoV-2 (16 of 18 [88.9%] with nucleocapsid protein antibodies and 17 of 18 [94.4%] with receptor-binding domain of spike protein antibodies); a substantial proportion (11 of 18 [61.1%]) had detectable cross-neutralizing antibodies. Twelve SARS03 adult survivors (10 women and 2 men) underwent postvaccination serologic examination. At 7 days after the first dose of vaccine, SARS03 survivors mounted significantly higher levels of neutralizing antibodies compared with controls (median inhibition: 89.5% [IQR, 77.1%-93.7%] vs 13.9% [IQR, 11.8%-16.1%] for BNT162b2; 64.9% [IQR, 60.8%-69.5%] vs 13.4% [IQR, 9.5%-16.8%] for CoronaVac; P < .001 for both). At 14 days after the second dose, SARS03 survivors generated a broader antibody response with significantly higher levels of neutralizing antibodies against variants of concern compared with controls (eg, median inhibition against Omicron variant, 52.1% [IQR, 35.8%-66.0%] vs 14.7% [IQR, 2.5%-20.7%]; P < .001).

Conclusions and Relevance

The findings of this prospective cohort study suggest that infection with SARS-CoV-1 was associated with detectable levels of antibodies that cross-react and cross-neutralize SARS-CoV-2, which belongs to a distinct clade under the same subgenus Sarbecovirus. These findings support the development of broadly protective vaccines to cover sarbecoviruses that caused 2 devastating zoonotic outbreaks in humans over the last 2 decades.
Conceptual framework for teaching civic education in the adult English as a second language classroom
Authors: Adversario Jan
Published: December 2022

Civic education provides adult English learners with the tools to be able to actively engage in their communities. This knowledge allows them to gain agency, develop a sense of belongingness, and facilitate lifelong learning. However, teaching civic education can be challenging for instructors for many reasons, such as prioritizing on developing the learners’ linguistic skills over their civic and citizenship knowledge. Thus, this article proposes a conceptual framework to incorporate civic education to the adult ESL classroom. Furthermore, it provides examples of relevant strategies and specific activities that illustrate the framework in action.
Verification of patient‐setup accuracy using a surface imaging system with steep measurement angle
Authors: Sasaki Fumihiro , Yamashita Yuusuke , Nakano Satoshi , Ishikawa Masayori
Published: December 2022

Purpose

We evaluate an SGRT device (Voxelan HEV‐600 M/RMS) installed with Radixact, with the view angle of the Voxelan's camera at 74 degrees. The accuracy of Voxelan with this steep angle was evaluated with phantom experiments and inter‐fractional setup errors of patients.

Methods

In the phantom experiments, the difference between the measured values of Voxelan from the truth was evaluated for translations and rotations. The inter‐fractional setup error between the setup using skin markers with laser localizer (laser setup: LS) and the setup using Voxelan (surface setup: SS) was compared for head and neck (N = 19), chest (N = 7) and pelvis (N = 9) cases. The inter‐fractional setup error was calculated by subtracting from bone matching by megavoltage computed tomography (MVCT) as ground truth.

Results

From the phantom experiments, the average difference between the measured values of Voxelan from the truth was within 1 mm and 1 degree. In all cases, inter‐fractional setup error based on MVCT was not significantly different between LS and SS by Welch's t‐test (P > 0.05). The vector offset of the LS for head and neck, chest, and pelvis were 6.5, 9.6, and 9.6 mm, respectively, and that of the SS were 5.8, 8.6, and 12.6 mm, respectively. Slight improvement was observed for the head and neck, and chest cases, however, pelvis cases were not improved because the umbilical region could not be clearly visualized as a reference.

Conclusion

The results show that SS in Voxelan with an installation angle of 74 degrees is equal to or better than LS.
Super Phosphorescence Resonance Energy Transfer (PRET) of Clusterization‐Triggered Emission Enables Full‐Spectrum Dynamic Room‐Temperature Afterglow
Authors: Liao Peilong , Wu Tongyue , Ma Cheng , Huang Jianbin , Yan Yun
Published: December 2022

Clusterization‐triggered emission is emerging as a powerful strategy leading to useful luminescence such as room‐temperature phosphoresce (CTE‐RTP), yet people's recognition on CTE‐RTP is still very limited, so that it remains challenging to achieve multicolor CTE‐RTP due to the difficulty in tailoring the clustering state of the atoms with lone pair electrons. The authors report that phosphorescence resonance energy transfer (PRET) can occur in the CTE‐RTP system, which enables fine‐tuning the color of the CTE‐RTP. Since the CTE‐RTP is a broad band in the range of 400–700 nm, and the dipole orientations are diverse in the CTE material, PRET can always occur between the CTE‐RTP and arbitrary fluorescent dyes to obtain delayed fluorescence ranging from green to near infrared. Because the lifetime of the delayed fluorescence depends on their molecular structure, dynamic afterglow can be facilely achieved in the ensemble of a PRET‐CTE‐RTP system, making it very appealing in anticounterfeiting.
Process Accumulated 8% Efficient Cu2ZnSnS4‐BiVO4 Tandem Cell for Solar Hydrogen Evolution with the Dynamic Balance of Solar Energy Storage and Conversion
Authors: Cai Hongwei , Zhao Weidong , Xiao Guohong , Hu Yucheng , Wu Xiaomin , Ni Huanyang , Ikeda Shigeru , Ng Yunhau , Tao Jiahua , Zhao Lingzhi , Jiang Feng
Published: December 2022

A process accumulated record solar to hydrogen (STH) conversion efficiency of 8% is achieved on the Cu2ZnSnS4‐BiVO4 tandem cell by the synergistic coupling effect of solar thermal and photoelectrochemical (PEC) water splitting with the dynamic balance of solar energy storage and conversion of the greenhouse system. This is the first report of a Cu2ZnSnS4‐BiVO4 tandem cell with a high unbiased STH efficiency of over 8% for solar water splitting due to the greenhouse device system. The greenhouse acts as a solar thermal energy storage cell, which absorbs infrared solar light and storage as thermal energy with the solar light illumination time, while thermoelectric device (TD) converts thermal energy into electric power, electric power is also recycled and added onto Cu2ZnSnS4‐BiVO4 tandem cell for enhanced overall water splitting. Finally, the solar water splitting properties of the TD‐Cu2ZnSnS4‐BiVO4 integrated tandem cell in pure natural seawater are demonstrated, and a champion STH efficiency of 2.46% is presented, while a large area (25 cm2) TD‐Cu2ZnSnS4‐BiVO4 integrated tandem device with superior long‐term stability is investigated for 1 week, which provides new insight into photoelectrochemical solar water splitting devices.
Regulation of 3d‐Transition Metal Interlayered Disorder by Appropriate Lithium Depletion for Li‐Rich Layered Oxide with Remarkably Enhanced Initial Coulombic Efficiency and Stability
Authors: Zhang Ying , Chen Zhefeng , Shi Xiaoyu , Meng Caixia , Das Pratteek , Zheng Shuanghao , Pan Feng , Wu Zhong‐Shuai
Published: December 2022

Li‐rich materials are among the most promising cathode materials for lithium‐ion batteries thanks to their high specific capacity. However, they exhibit poor structural stability, resulting in low initial Coulombic efficiency and limited cycle stability. Herein, a long‐neglected Li‐deficient state is realized for a Co‐free lithium‐rich cathode through a facile calcination medium‐induced surface‐corrosion (CMISC) strategy for alleviating the aforementioned drawbacks. The as‐constructed Li‐deficient lithium‐rich cathode of Li1.2‐σMn0.6Ni0.2O2 (d‐LMNO) exhibits an enhanced capacity of 272 mAh g−1, improved initial efficiency of 84.5%, and cycle stability with 82.0% retention over 200 cycles. In addition, multiple in situ and ex situ investigations confirm the appropriate lithium depletion regulated 3d‐transition metal interlayered disorder, resulting in excellent structural reversibility of d‐LMNO. Also, theory simulations suggest that the crystal structure with Li‐defects has lower energy and Li‐diffusion energy barrier when the coordination interlayer 3d‐metal has more Ni closer to the diffused Li, meaning less interlayered disorder. And the migration of Li close to the vacancy is dominated by a tetrahedral site hopping path in the presence of additional vacancies around the Li vacancy, which has a low migration energy barrier. Moreover, similar results achieved in Co‐containing Li‐rich cathodes further demonstrate the universality of this simple CMISC strategy, exhibiting great potential for performance improvement and applicability.
Mifepristone for miscarriage treatment in Utah: A survey of clinician knowledge and assessment of an educational video on future use
Authors: Kaiser Jennifer E. , Kurtz Theresa , Glasser Annabah , Brintz Benjamin J. , Gawron Lori M. , Turok David K. , Sanders Jessica N.
Published: December 2022

Objectives

We aimed to: (a) describe current use of mifepristone for early pregnancy loss (EPL) management in Utah, (b) identify predictors of knowledge pre‐ and posteducational video, and (c) explore postvideo impacts on the likelihood to use mifepristone. Mifepristone is subject to the Food and Drug Administration's (FDA) Risk Evaluation and Mitigation Strategy (REMS) requirements.

Methods

Between September 2020 and March 2021 we surveyed Utah clinicians from six specialties caring for people experiencing EPL, recruited through professional organizations and hospital listservs. Participants viewed a 3.5‐minute educational video on mifepristone for EPL and completed pre‐ and postvideo questionnaires. We evaluated predictors of high prevideo and improved postvideo knowledge using random forest regression conditional importance measures and partial dependency plots. We described current mifepristone use and video effects on likelihood to use mifepristone.

Results

Of 506 participants, most specialize in emergency medicine (172, 34%) and practice in private settings (253, 51%). Two‐thirds had heard of mifepristone (328/471, 70%). Of 176/471 (37%) attempting provision of mifepristone, actual provision occurred for 59% (104/176). Baseline knowledge scores were low (mean 4.81/13 [37%] correct). Predictors of high prevideo knowledge include provision or attempted provision of mifepristone, having heard of mifepristone, providing EPL management expectantly or via medication, and specialty type. Mean postvideo knowledge scores improved by 3.27 points (68% improvement, paired t‐test; 95% confidence interval 2.82–3.72, p < 0.0001). Postvideo, 66% (242/364) stated they are much more or somewhat more likely to use mifepristone, with compliance with FDA requirements cited as a barrier to utilization.

Conclusions

Among Utah providers, baseline mifepristone knowledge and use for EPL management are low. An educational video improved knowledge and likelihood of use, but FDA REMS requirements continue to be a barrier to including mifepristone in medication management of EPL.
Autosomal dominant inheritance with sex‐limited manifestation: An unusual mode of transmission in humans and animals
Authors: Happle Rudolf , Eyerich Kilian
Published: December 2022

Autosomal dominant, sex‐limited inheritance is a distinct mode of transmission that should not be conflated with X‐linked inheritance. From animal studies, we know that sex‐limited inheritance implies the chance to “turn off” some genes in either males or females, in order to meliorate the phenotype, for example, by improving the fecundity. In this way, sex‐limited genes play an important role in the evolution of diverse species of animals. In human genetics, however, the biological significance of sex‐limited genes is unknown until today. When screening the literature, we found, thus far, three human examples of sex‐limited transmission. Autosomal dominant, male‐limited inheritance has meticulously been studied in a particular form of precocious puberty. Limitation to females was described in autosomal dominant lymphedema of the CESLR1 type, being underpinned by convincing molecular findings. Another example is white lentiginosis of Grosshans that shows clinical evidence of such mode of transmission although molecular findings are lacking as yet. In the animal kingdom, autosomal dominant sex‐limited inheritance is a well‐established phenomenon that has extensively been studied in various species such as butterflies, damselflies, fish (cichlids), and birds. Hence, at this point in time, it seems likely that other human examples of this mode of inheritance have previously been reported or will be published in the future.
Expansion of the clinical and molecular spectrum of WWOX‐related epileptic encephalopathy
Authors: Chong Shuk Ching , Cao Ye , Fung Eva L. W. , Kleppe Soledad , Gripp Karen W. , Hertecant Jozef , El‐Hattab Ayman W. , Suleiman Jehan , Clark Gary , von Allmen Gretchen , Rodziyevska Olga , Lewis Richard A. , Rosenfeld Jill A. , Dong Jie ,   Undiagnosed Diseases Network, Wang Xia , Miller Marcus J. , Bi Weimin , Liu Pengfei , Scaglia Fernando
Published: December 2022

WWOX biallelic loss‐of‐function pathogenic single nucleotide variants (SNVs) and copy number variants (CNVs) including exonic deletions and duplications cause WWOX‐related epileptic encephalopathy (WOREE) syndrome. This disorder is characterized by refractory epilepsy, axial hypotonia, peripheral hypertonia, progressive microcephaly, and premature death. Here we report five patients with WWOX biallelic predicted null variants identified by exome sequencing (ES), genome sequencing (GS), and/or chromosomal microarray analysis (CMA). SNVs and intragenic deletions of one or more exons were commonly reported in WOREE syndrome patients which made the genetic diagnosis challenging and required a combination of different diagnostic technologies. These patients presented with severe, developmental and epileptic encephalopathy (DEE), and other cardinal features consistent with WOREE syndrome. This report expands the clinical phenotype associated with this condition, including failure to thrive in most patients and epilepsy that responded to a ketogenic diet in three patients. Dysmorphic features and abnormal prenatal findings were not commonly observed. Additionally, recurrent pancreatitis and sensorineural hearing loss each were observed in single patients. In summary, these phenotypic features broaden the clinical spectrum of WOREE syndrome.
The Role of Alzheimer’s disease relevant Tau modifications in Neurodegeneration and Mitochondrial dysfunction
Authors: Guha Sanjib K , Nehrke Keith , Johnson Gail VW
Published: December 2022

Background

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder whose pathological hallmarks include intraneuronal neurofibrillary tangles (NFTs) composed of the microtubule‐associated protein Tau. Tau isolated from AD brain exhibits abnormally high levels of post‐translational modifications (PTMs) including phosphorylation and acetylation at specific epitopes that increase with disease severity and age. In addition, mitochondrial dysfunction is an early feature of AD, and abnormal, toxic tau PTMs may contribute to disease pathogenesis. A major bottleneck in understanding the mechanisms behind the neurotoxicity of pathological forms of Tau is the lack of genetically tractable models that can recapitulate the effects of Tau PTMs in a short time frame without artifacts associated with Tau overexpression.

Method

Human 0N4R Tau (wild type) was expressed in touch receptor neurons through single‐copy gene insertion. Mutations were introduced into the single‐copy tau transgene through CRISPR‐Cas9 genome editing, including T231E and T231A, to mimic phosphorylation and phospho‐ablation of a commonly observed pathological epitope, respectively, and K274/281Q, to mimic disease‐associated lysine acetylation. We then assessed their impact on age‐dependent response to light touch, neurodegeneration, and mitochondrial parameters such as abundance, morphology, trafficking, and turnover, using fluorescent biosensors including mito‐mKeima.

Result

Unlike existing tau overexpression models, C. elegans single‐copy expression of wild type human tau did not elicit overt pathological phenotypes at baseline. However, strains expressing disease associated PTM‐mimetics (T231E and K274/281Q) exhibited reduced touch sensation and neuronal morphological abnormalities that increased with age. Remarkably, the PTM‐mimetics selectively impaired mitophagy following mitochondrial oxidative stress, but had no effect on macroautophagy, and furthermore reduced mitolysosomal trafficking.

Conclusion

Single copy expression limits pathological phenotypes to strains expressing disease‐associated Tau mutants. In addition to overt pathology, these mutants eliminate oxidative stress‐induced mitophagy and reduce trafficking of mitolysosomes. Our findings highlight a selective mechanism through which disease‐associated Tau PTMs may suppress compensatory responses to mitochondrial stress that occur with age and provide a new perspective into the pathogenic mechanisms underlying AD.
Ensemble approach for early detection and classification of stages of Alzheimer’s disease
Authors: C R Nagarathna , M M Kusuma
Published: December 2022

Background

The proposed model is applied to MRI dataset collected from ADNI and kaggle dataset.

Method

We propose an ensemble model that is combination of VGG19 and additional layers of deep neural networking with a specific configuration for feature extraction and classification.

Result

Received 93.4% of accuracy for ADNI dataset and 95.52% of accuracy for kaggle dataset

Conclusion

We done our Experiments with MRI dataset collected from ADNI and kaggle and performance metric values are compared. It shows that proposed model gives most promising result for both datasets It is considered to be a high performance model.