bluuebunny/crossref_metadata_2025 huggingface dataset:
Adherence to chest physiotherapy, airway clearance techniques and physical exercise by children and adolescents with cystic fibrosis
Authors: Pereira Módolo Larissa , Bergamim Uliana Luana , Mayrink Gonçalves Liberato Fernanda , Da Silva Baptista Arpini Luana , Helena Santuzzi Cíntia , Nunes Cruz Melotti Roberta de Cássia , Marini Paro Flavia
Published: April 2024

Introduction: chest physiotherapy, airway clearance techniques, and physical exercise are associated with better outcomes in cystic fibrosis, but adherence to these recommendations remains a challenge.
Objective: to assess adherence to chest physiotherapy, airway clearance techniques, and physical exercise by children and adolescents with cystic fibrosis and analyze the factors related to adherence.
Methods: retrospective study of children and adolescents with cystic fibrosis from a pediatric referral center in Brazil. Data were collected from electronic records of the multidisciplinary team responsible for caring for these patients at the referral center.
Results: the sample included all 83 patients registered at the referral center, with a mean age of 7.88 ± 4.88 years. Among them, 28.9% did not have weekly chest physiotherapy, 66.3% did not practice physical exercise regularly, and only 38.6% practiced airway clearance techniques from 6 to 7 times a week. Higher adherence to airway clearance techniques was associated with higher mean age (p<0.01) and correlated with FEV1 (r=-0.39; p=0.03), FEF25-75% (r =-0.36; p=0.02), FEV1/FVC (r =-0.43; p=0.01) and lower mean Shwachman-Kulczycki Score (r=-0.34; p<0.01). Higher physical exercise adherence was associated with a higher mean age (p<0.01). Individuals using public financing of physiotherapy services had a lower Shwachman-Kulczycki Score (p=0.02) than those using non-public services. The metropolitan region had a higher percentage of individuals using non-public services than other regions (p<0.01).
Conclusion: adherence to chest physiotherapy, airway clearance techniques and physical exercise was lower than recommendations. Airway clearance techniques and physical exercise adherence increased with age, and airway clearance techniques adherence was associated with the high severity of disease. These results suggest that patients only increase adherence when they get older and the disease worsens, highlighting the need for strategies to increase adherence early.
Temporal evolution of traffic accident mortality rates in the State of São Paulo, Brazil, in the period 2009-2019
Authors: Cecilio Bebiano Beatriz , Carlos de Abreu Luiz , Carboni de Souza Rafael , Furlan Cleber , Luiz Figueiredo José , Pires da Costa Woska , Naildo Cardoso Leitão Francisco , Miller Reis Rodrigues Luciano
Published: April 2024

Introduction: external causes are considered a public health problem in the world, associated with socioeconomic, political, and cultural diversities. Among them, traffic accidents stand out.

Objective: to assess the trend in traffic accident mortality for each sex in the state of São Paulo, Brazil.

Methods: ecological study of time series analyses. Secondary data referring to deaths from traffic accidents by place of residence in the state of São Paulo, Brazil, in the period 2009 - 2019 were used.

Results: the total mortality rate in 2019 for females is 39.80 and for males, 185.85, with a reduction of 4.96% per year for both sexes. The trends in mortality from traffic accidents for females proved to be stationary for motorcyclists, motorized tricycle, pickup truck, heavy transport vehicle, and bus occupants at the end of the study period. For males, the same pattern was observed, but only for truck, heavy transport vehicle, and bus occupants. In the rest of the vehicles, the mortality rate showed decreasing trends.

Conclusion: the highest number of deaths occurred among males (81.38%), aged between 20 and 49 years (58.70%), single (49.12%), on public roads (46.73%) and hospitals (45.64%). Females have more stationary trends than males.
A EDUCAÇÃO ETNICO-RACIAL COMO BASE PARA UMA PERSPECTIVA DECOLONIAL NA FORMAÇÃO DE PROFESSORES
Authors: Renata Meira Veras  , Sheyla Fernandes
Published: April 2024

Os regimes coloniais são racialmente organizados e o racismo é o principal instrumento de organização e controle da população negra. Assim, partimos do pressuposto de que o sistema educacional tem implicação direta nas práticas racistas, uma vez que os conteúdos e currículos são produtos de valores e crenças assentadas em uma visão de mundo hierarquicamente organizada a partir da diferenciação racial. Sendo assim, neste capítulo iremos refletir sobre o papel da decolonização dos currículos dos cursos de licenciatura através da educação étnico-racial na construção de crenças desassociadas da divisão hierárquica de raças. Descolonizar as Universidades, seus currículos e as práticas pedagógicas pode ser um caminho profícuo para construir novas crenças desassociadas da conformação social baseada na diferenciação por raça. A formação de subjetividades emancipatórias está, portanto, relacionada ao estabelecimento de novas crenças e isto pode ser possibilitado pela postura pedagógica ética e democrática
Identification of Extremely Virulent Infectious Bursal Disease Virus Via Molecular and Histological Methods in Broiler Chickens
Authors: Nasser Ammar Taleb , Al-Azzawi Amer , Al-Agele Ramzi , Al-Ajeeli Karim
Published: April 2024

Infectious bursal disease (IBD) is caused by an RNA virus belonging to the Avibirnavirus genus within the Birnaviridae family. The global prevalence of infectious bursal disease virus (IBDV) is a significant concern, affecting birds of all ages. Birds infected with IBDV exhibit symptoms, such as depression, bleeding in the thighs and pectoral muscles, and enlargement of the bursa. This study aimed to identify predominant IBDV serotypes using molecular methods and to gain insights into the resulting pathological conditions in infected chickens. Additionally, the study investigated the viral sequence and the relationship between a local Diyala isolate and reference strains from the Genebank. In the current study, the IBDV was isolated from broiler chickens aged 2-3 weeks from 15 farms in the Diyala Governorate of Iraq. A total of 15 samples, each from a different farm, were collected. Necropsy samples were obtained from various organs of broiler chickens, including the bursa of Fabricius, lungs, liver, and kidneys. Specific primers targeting the VP2 gene were used for reverse transcription-polymerase chain reaction (RT-PCR) analysis. The RT-PCR analysis yielded a 727 bp fragment, confirming the presence of IBDV in 10 out of the 15 samples. One strain was assigned the accession number LC498531 in the NCBI database. Phylogenetic analysis using the neighbor-joining tree program revealed three distinct groups. All examined regional samples (S1) were situated within the constructed tree. Five samples formed a specific group, indicating a close relationship. Histological examination of the tissues showed visible alterations such as degeneration, necrosis, and infiltration of inflammatory cells, particularly heterophils, providing clear evidence of the disease. In conclusion, this study confirmed the presence of IBDV in broiler chickens from multiple farms in Iraq’s Diyala Governorate, highlighting distinct clustering patterns in viral sequences. Moreover, the study confirmed the virus's presence using conventional RT-PCR, with histological examination supporting the findings.
Keywords: Broiler chicken, Bursal enlargement, Infectious bursal disease, RT-PCR
Effects of Body Condition, Anatomical Measurement, and Age on the Cumulative Number of Individual Egg Production and Laying Pattern in First Laying Hens
Authors: Prayogi Heni Setyo , Nurgiartiningsih Veronica Margareta Ani , Sjofjan Osfar
Published: April 2024

The individual egg production capacity of laying hens plays an outstanding role in achieving total production within a flock, which is affected by several internal and external factors. This study aimed to evaluate the effect of body condition, anatomical measurement, and age at the first laying (AFL) on the cumulative number of individual egg production (CNIEP) and laying pattern. Therefore, 172 Isa Brown laying chickens were investigated. Data on body condition and anatomical measurement were collected at the age of 16 weeks, while data on production was collected during 21 weeks of production (18-39 weeks). The obtained data were analyzed by Partial Least Square- Structural Equation Modeling (PLS-SEM) using smartPLS. The findings revealed that CNIEP could be predicted by body condition, anatomical measurement, and AFL. Compared to body condition and anatomical measurements, AFL was the most prominent factor in CNIEP. Body condition, anatomical measurement, AFL, and CNIEP had weak effects on the Isa Brown laying chickens’ patterns.
Keywords: Anatomical measurement, Individual egg production, Laying pattern
Differential Gene Expression Profiling during Avian Immune Organ Development: Insights from Thymus and Bursa of Fabricius Transcriptome Analysis
Authors: El Helaly Goher Mohamed Naguib , Moghaieb Reda Elwan , El- Menawey Mohamed Abdel-Raham , Ramzy Stino Farid Kamal
Published: April 2024

Pluripotent hematopoietic stem cells undergo maturation to regenerate blood cells. T-cell and B-cell maturation from common lymphoid progenitors (CLPs) is regulated by distinct transcription factors and signaling pathways. Notch signaling, GATA3, and TCF1 drive T-cell fate, while EBF1, PU.1, E2A, Pax5, TCF1, and Foxo1 regulate B-cell differentiation. Alterations in these factors can cause lineage deviations. Gene expression profiling of the chick thymus and bursa reveals dynamic expression patterns of transcription factors, cytokines, and signal molecules. Notch1 and Dll1 expression that increase during later stages indicate the ongoing role of Notch signaling in T-cell lineage maintenance. The current study aimed to identify differentially expressed genes during the development of the avian immune organs, focusing on the thymus and bursa using 24 Ross 308 avian breed. The mRNA libraries from these organs were analyzed using quantitative Real-time PCR analysis at six time points spanning the embryonic ages (days 15 and 18) and post-hatch age (days 3, 7, 14, and 28). The data for the gene expression indicated significant variations across different stages of immune organ development. Differential gene expression was observed between sorted T and B-cells, with GATA3, CD3e, CD4, and Ptprc showing higher expression in the T-cell population, and Pax5 and CD81 exhibiting higher expression in the B-cell population. Notably, ENO1 and IRF4 showed higher expression in T-cells at E15 and B-cells at E18. The study highlights the importance of regulatory factors and genes in maintaining cellular identity, furthers the understanding of avian immunology, and has the potential for improving poultry health and studying immune-related diseases in humans. These findings pave the way for further research on the role of biochemical components under important disease conditions in avian immunology and their potential applications for poultry health.
Keywords: Avian lymphocyte, B-cell maturation, Gene expression, Regulatory elements, T-cell
A Framework for Managing Disputes Over Intellectual Property Rights in Traditional Knowledge
Authors: Munzer Stephen
Published: April 2024

Major controversies in moral and political theory concern the rights, if any, Indigenous peoples should have over their traditional knowledge. Many scholars, including me, have tackled these controversies. This Article addresses a highly important practical issue: Can we come up with a solid framework for resolving disputes over actual or proposed intellectual property rights in traditional knowledge?

Yes, we can. The framework suggested here starts with a preliminary distinction between control rights and income rights. It then moves to four categories that help to understand disputes: nature of the traditional knowledge under dispute; dynamics between named parties to disputes; unnamed Indigenous claimants; and the various normative systems (for example, custom, U.N. documents, treaties, statutes, administrative regulations) within which disputes are decided. Throughout, examples that inform the framework come principally from Indigenous peoples in the Pacific rim. Lastly the Article tests the framework against some disputes over traditional knowledge in Samoa and New Zealand.

This framework is comprehensive and sensitive to context. It is flexible regarding which normative systems are best suited to settling disputes. A test run shows that the framework helps to resolve practical legal issues.
Reviving Indian Country: Expanding Alaska Native Villages’ Tribal Land Bases Through Fee-to-Trust Acquisitions
Authors: Studler Alexis
Published: April 2024

For the last fifty years, the possibility of fee-to-trust acquisitions in Alaska has been precarious at best. This is largely due to the Alaska Native Claims Settlement Act of 1971 (ANCSA), which eschewed the traditional reservation system in favor of corporate land ownership and management. Despite its silence on trust acquisitions, ANCSA was and still is cited as the primary prohibition to trust acquisitions in Alaska. Essentially, ANCSA both reduced Indian Country in Alaska and prohibited any opportunities to create it, leaving Alaska Native Villages without the significant territorial jurisdiction afforded to Lower 48 tribes. However, recent policy changes from the Department of Interior reaffirmed the eligibility of trust acquisitions post-ANCSA and a proposed rule from the Bureau of Indian Affairs signals a favorable presumption of approval for Alaska Native fee-to-trust applications. This Note reviews the history and controversy of trust acquisitions in Alaska, and more importantly, it demonstrates the methods in which Alaska Native Villages may still acquire fee land for trust acquisitions after ANCSA.
SOCIAL PROBLEMS IN MODERN INDIA
Authors: Lamba Era , Gupta Rakhi , Singh Lamba Rudra Pratap
Published: April 2024

In modern India, several social problems persist, reflecting the complexities of a rapidly evolving society. Agrarian distress exacerbates rural poverty, leading to migration and unemployment. Urban areas grapple with the problem of slums and high rates of joblessness, perpetuating cycles of poverty and inequality. Drug abuse and juvenile delinquency afflict vulnerable segments of the population, hindering social progress. Crime rates, including instances of communal violence, highlight underlying societal tensions. The deeply entrenched dowry system perpetuates gender discrimination and domestic violence. Despite legislative efforts, domestic violence remains a pervasive issue, undermining familial stability and individual well-being. Addressing these multifaceted challenges requires holistic approaches, including socioeconomic reforms, educational initiatives, and community engagement, to foster a more equitable and harmonious society.
V. V. Putin’s Idiolect as an Object of Study in Modern Linguistics
Authors: Fesenko O.P.
Published: April 2024

In the article V. V. Putin’s idiolect is described based on the material of scientific articles of the last 20 years. The results of the analysis of the phonetic component of the president’s speech, lexical and phraseological, morphological, syntactic and stylistic, are presented. It was found out that the studies reveal discrepancies in the description of some components of the idiolect. In addition, the idiolect is practically not analysed from the standpoint of rhetoric, as well as in diachrony
Existential Approach as an Educational Model of the Future
Authors: Maltseva S.M. , Cherkesov T.A.
Published: April 2024

The article points out the necessity of changing the approach in the education of the younger generation. The author analyses the main ideas of existentialism as a philosophical movement, states the necessity of using existential approach within the framework of education of the younger generation. The author considers existential approach as a possible educational model of the future.
The Image of a Teacher-Choreographer in the Modern Sociocultural Space
Authors: Sabantseva T.V.
Published: April 2024

The purpose of the study is to update information about the current state of the image of a teacher-choreographer, about changes generated by the influence of sociocultural space. The main characteristics of the image of a teacher-choreographer, previously presented in scientific works, are specified. The research with respondents was conducted, in the course of which the main potential of the pedagogue-choreographer’s duties was prioritised. The desired needs of respondents for an additional focus of knowledge during the training period were identified.
Filioque as a Problem of Ontology, Epistemology, Theology, and General Linguistics (Using Graphic Models for Visualizing a Consistent Resolution of the Problem)
Authors: Lobovikov V.O.
Published: April 2024

The subject-matter of the study was ontological and epistemological aspects of the theological problem of the filioque, and the research methods were logical-linguistic analysis and graphic modelling of these aspects of this problem, in particular the construction of theological analogues of logical squares and hexagons. The scientific novelty lies in the fact that the mentioned non-trivial analogues are constructed for the first time; they have not been published anywhere before. The results of the study are important in the formation of the theoretical philosophical and linguistic foundations for overcoming the doctrinal split of the Universal Church into the Western and Eastern ones.
Ethos. Social Aspects of Anthropological Phenomenon
Authors: Razаva А.L.
Published: April 2024

The appeal to the concept of “ethos” is due to the ever-increasing interest in the boundaries and ultimate foundations of the human. There are two levels of understanding ethos: philosophical-anthropological and sociological. Ethos, or individual aspects of what can be directly included in the phenomenon of ethos, has been considered in philosophical anthropology and social philosophy. The concept of “ethos” and the entire body of its attributes at the philosophical and sociological level can serve as the basis of a methodology for considering the ultimate foundations and boundaries of the human, which is extremely important in the context of the dehumanization of social, cultural and humanitarian processes.
Features of Semantic Relations of Stimuli and Responses in the Associative Activities of Educational Bilinguals
Authors: Guts E.N. , Tao Ye
Published: April 2024

The article examines the type of semantic connections between stimuli and responses shown during free association in an experimental situation with the participation of educational bilinguals — Chinese students studying Russian. It was assumed that the predominance of certain methods of response in educational bilinguals is due not only to the syntactic connections of words of different parts of speech, but also to a greater or lesser breadth of mastery of the syntagmatic and paradigmatic relations of units of the language being studied. Analysis of the results of the associative experiment in the aspect of classifying semantic relations with stimuli showed the highest frequency in any associative field of the deployment reaction, which is associated with the dominance of the tactic of “attributing a sign to an object”, as well as with the educational nature of bilinguism — foreign speakers reproduce the syntax (S — R) used by them in Russian language classes in various exercises and texts.
The English Term Normcore: Transformation in Fashion and Problems of Translation
Authors: Dolgova T.V. , Ohotnikova E.P.
Published: April 2024

The aim of the paper is to study the English term normcore, which is a neologism in the term system of the fashion industry; to identify the reasons for its appearance and structural composition, as well as to find an adequate translation into Russian. The authors also give examples of other fashion terms with the morpheme -core in the postposition.
Behavioural Analytics in Policing Data-Driven Offender Management: Assessing the Evidence Base
Authors:   , Babuta Alexander
Published: April 2024

This doctoral thesis explores the use of behavioural analytics and data-driven offender management within UK policing. The findings are based on semi-structured interviews with criminal justice practitioners who have been directly involved in the development of such projects, and a process evaluation of a major data-driven offender management project delivered by one of the UK’s largest police forces. The research explored the potential opportunities offered by new data-driven risk assessment tools, and sought to examine the barriers to successful implementation when the technology is deployed in an operational policing context. The process evaluation highlighted specific practical challenges associated with implementing a new data-driven system in an operational offender management context. The implications of these findings for future policing practice are explored, focussing on how such technology should be piloted and evaluated to assess its potential real-world benefits and limitations. The findings and discussion will be of interest to criminal justice practitioners and policymakers involved in developing or implementing new data-driven offender risk assessment tools in the UK criminal justice system.
INVESTIGATIONS INTO THE DUCTILITY OF LAP JOINTS IN LOW STRENGTH REINFORCED CONCRETE BEAMS
Authors:   , Karkarna Yakubu Mustapha
Published: April 2024

The most current standardised design guidelines for tension laps originated fromthe Fib Model Code 2010. These guidelines have had a significant impact on the newly proposed version of Eurocode 2, set to be published in 2023. The existing Eurocode 2 detailing guidelines can result in significantly longer lap jointsthan earlier design guidelines, such asthe replaced British Code (BS 8110-1). Furthermore, the Model Code 2010 necessitates lengthier laps than Eurocode 2. This research describes the analytical and experimental investigations conducted at the University of West London concrete laboratory to investigate the influence of rebar laps on the ductility of lapped sections. The tests were designed specifically to evaluate the effectiveness oflonger tension lapsin transmitting forces between the two-lap splice rebars. Thework described in this thesis is conducted in two stages. The first stage is an experimentaltest conducted on simply supported reinforced concrete beams with lap splices under four points bending with varying lap lengths and two reinforcement bar types. The analyses and experimental results for all the samples are described,with the deflection at the midspan of the beam measured using a built-in AEP TC4 transducer, and the result stored in a LabVIEW-based software attached to the actuator. In addition to the in-built displacement transducer, one variable displacement transducer was placed at the centre of the bottom face of the beam to record displacementfor more accuracy. The test showed that variation in lap splice length increases the stiffness and resistance of the sample. The results demonstrated how the samples’ behaviour changed, when transverse cracks initially appeared aslap joint failure approached. The detailed examination of the modelled and experimental results entails a comparison ofthe splice length’s ultimate performance with current Eurocode design recommendations. The second section describes the numerical model,which is based on nonlinear analysis. The samples are replicas of the simply supported concrete beams. The model allows the stress-strain behaviour of structural concrete to be simulated to failure and also considers the nonlinear behaviour in compression, tension, cracking and crushing of concrete. The simulation findings were then compared to the laboratory testresults. Based on the analysis conducted, it was observed that increasing the lap splices beyond 500 has no additional benefit for increasing its strength. The findings also showed that the stainless steel reinforced concrete beam deformations, which coincide with 35% and 62% of the maximum bending moment were higher than those of mild steel reinforced concrete beam. Moreover, the research also concluded that there is sufficient ductility and rotation at lap ends. However, designing the lap with a factor of 1.2 would lead to rebar congestion and unsustainable design practices in terms of sustainability.
LA DESCARBONIZACIÓN JUSTA DE LAS CIUDADES: UN ANÁLISIS DE LA MISIÓN EUROPEA Y SU IMPLEMENTACIÓN EN ESPAÑA
Authors: Ezquerra Lázaro Irene , Novales Beatriz , García-Gil Berbería Alejandro , Camiscia Caren , Nardini Santiago
Published: April 2024

La Unión Europea (UE) ha establecido una misión ambiciosa para acelerar el progreso hacia los objetivos del Acuerdo de París (2015) y del Pacto Verde Europeo (2020): al menos cien ciudades europeas alcanzarán la neutralidad climática antes de 2030. Aunque la UE ha proporcionado herramientas a las ciudades para integrar aspectos medioambientales y económicos en el proceso de diseño e implementación local
de la misión, este artículo sostiene que no se ha prestado suficiente atención a la dimensión social de la transición. Las autoras extraen conclusiones de su observación del contexto español, del análisis de estrategias locales y de entrevistas formales e informales con representantes municipales. El artículo explora el concepto de justicia social en el contexto de transición hacia la neutralidad climática, y destaca la
necesidad de integrar este enfoque desde el principio, asegurando que el diagnóstico de las desigualdades preexistentes, la participación de la ciudadanía y la evaluación de incentivos y co-beneficios contribuyen al diseño, implementación y evaluación de las políticas climáticas. Una colaboración estrecha entre departamentos municipales y niveles administrativos es fundamental para garantizar la coherencia y
eficacia de las políticas. En conclusión, el artículo insta a reevaluar los mecanismos actuales para promover una transición socialmente justa e inclusiva, desde un enfoque holístico que integre las dimensiones ambiental, económica y social.
DESIGN AND IMPLEMENTATION OF BICYCLE USING SOLAR PANELS
Authors: Maheswara Rao Mr. P. , Priya A.Kundana , Reddy A.Karthik , A.Poojitha  , B.Likitha  , G.SaiManikanta
Published: April 2024

In the current context, the integration of a Solar Hybrid Bicycle system offers a promising solution to the pressing issues of fuel consumption and pollution. It's undeniable that the carbon dioxide emissions from vehicle exhausts contribute significantly to the escalating global warming crisis. With fuel prices on the rise in India and worldwide, the urgent need to explore alternatives to preserve natural resources becomes paramount.Encouraging the adoption of hybrid vehicles can effectively mitigate CO2 emissions and lower fuel expenses. Hence, the emergence of solar bicycles as electric vehicles presents a viable alternative by harnessing solar energy to charge batteries, thus powering the motor. Given India's abundant sunshine for approximately nine months a year, the concept of solar bicycles holds immense practicality in the region.To address this need, we've developed a Hybrid bicycle that integrates both solar energy and pedal-generated power through a dynamo to charge the battery and propel the bicycle. The system features an efficient solar/electric power generation unit mounted on the rear of the bicycle, capturing sunlight to charge the battery consistently. During periods of limited sunlight, the bicycle seamlessly transitions to battery power.To regulate motor speed, an accelerator is incorporated, providing precise control over power delivery. This innovative approach not only reduces operational costs but also enhances overall efficiency. Capable of reaching speeds of 25km/hr while accommodating an average-weight rider, the Solar Hybrid Bicycle emerges as a cost-effective alternative to conventional automobiles, underscoring the necessity for its widespread production and adoption
IOT-BASED SMART SALINE LEVEL AND HEALTH MONITORING SYSTEM
Authors: Aruna S  , Srinivasa Naik S  , Neha G  , Priyanka P  , Mohammed Ayesha Shaik , Manaswini K Veda , Sindhu K
Published: April 2024

The many uses of saline solution include as providing temporary fluids when there is under or no hydration among the trauma cases. In addition, they participate in the control of salt and the levels of electrolytes in the body. To maintain the level of a saline bottle, hospital nurses or aides prime responsibility is to check it on a regular basis. The failure to replace them in time may result in a reversal of blood flow, compromising the patient’s life. An Internet of Things (IoT)-based Smart Saline Level was developed to solve this issue and to provide an automated and efficient solution for remote monitoring. The Proposed system employs Internet of Things (IoT) technology, integrating NodeMCU, a load cell amplifier (HX711), Arduino UNO, Pulse oximeter (MAX 30100) sensor, DHT11 Sensor and a voltage regulator(L7805). The load cell, in combination with the HX711 amplifier, accurately measures the weight of the saline bottle. MAX30100 sensor measures Heart Rate & Oxygen saturation (SPo2) levels in blood. DHT11 Sensor detects the Humidity and Temperature levels. All the data is transmitted to the Arduino UNO, which serves as a master, the NodeMCU facilitates wireless communication, relaying the collected data from the Arduino UNO to the designated IoT cloud platform for remote monitoring.
SMART FARMING DECISION SUPPORT SYSTEM FOR PRECISION AGRICULTURE
Authors: Tirumala Rao Mr. P. , Balaka Anil  , Siddhartha Ganisetti , Shyam Yerninti , Pawan Rao Bandaru
Published: April 2024

The incorporation of IoT (Internet of Things) innovation within agricultural practices, often referred to as precision agriculture, has gained significant attention in recent years. This paper presents the development and implementation of a Smart Farming Decision Support System aimed at enhancing agricultural efficiency, productivity, designed to optimize water management and resource utilization in precision agriculture. The system utilizes various sensors, microcontrollers, and web technologies to monitor environmental conditions and automate irrigation processes in real-time. A detailed description of the system architecture along with its hardware components, software implementation, deployment strategy, experimental results, and potential impact on agricultural practices is provided.
Combination of Remimazolam, Remifentanil Anesthesia, and Enteral Nutrition Support Restores Vital Signs and Nutritional Status of Patients Undergoing Intravascular Interventional Therapy for Intracranial Aneurysms
Authors: Zheng Deli , Wang Juzeng , Chen Huan , Li Huili , Shi Ji , Meng Li
Published: April 2024

Ninety-eight patients from our hospital were included in the study from March 2022 to March 2023. The patients were divided into two groups: 49 patients received propofol + remifentanil in the control group and 49 patients received remimazolam + remifentanil in the observation group. Postoperatively, the control group accepted parenteral nutrition support, while the observation group accepted enteral nutrition support. The observation group experienced a longer duration of consciousness loss but shorter times for consciousness recovery and trachea extubation than the control group. Although both groups experienced elevated mean blood pressure, heart rate, norepinephrine, angiotensin II, and plasma cortisol levels during tracheal intubation and extraction, the observation group showed differences compared to the control group. No statistical significance was discovered in the incidence of postoperative adverse reactions between the two groups (P = 0.29). Furthermore, tumor necrosis factor-α and interleukin-6 levels were lower in the observation group than in the control group, while total protein, albumin, and hemoglobin levels were higher. Overall, remimazolam combined with remifentanil demonstrated superiority over propofol combined with remifentanil in the perioperative period for patients undergoing intravascular interventional therapy for intracranial aneurysms.
Enhancing Ischemic Stroke Management with Cluster Nursing: A Comparative Study on the Effects of Ginkgo biloba Diterpene Lipid Amine Treatment
Authors: Li HuiJun , Zeng Weijuan , Yang EnYan , Fu Rui , Li Wei , Wang Yan Yan , Fu QiMei
Published: April 2024

This study aimed to investigate the effect of cluster nursing on the management of ischemic stroke patients receiving Ginkgo biloba diterpene lipid amine treatment. This study was conducted on 197 patients from the Neurology Department of the author’s hospital from December 2021 to December 2022. These patients were divided based on their admission time into two groups: a control group comprising 98 patients who received routine nursing care and an observation group of 99 patients who were administered cluster nursing. This study evaluated and compared the incidence of nutritional intolerance events, nursing-related adverse events, and the overall quality of life among these groups. Results indicated a statistically significant reduction in the incidence of nutritional intolerance (P < 0.05) and nursing adverse events associated with enteral nutrition support (P < 0.05) in the observation group compared to the control group. Furthermore, the observation group exhibited higher scores in family role, energy, and verbal ability (P < 0.05), suggesting an improvement in the quality of life. These findings highlight the effectiveness of the cluster nursing approach in improving the management and outcomes for ischemic stroke patients in terms of reducing nutritional intolerance and nursing adverse events, thereby significantly enhancing the quality of life.
Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models
Authors: Zheng Pan , Li Xue-Yang , Yang Xiao-Yu , Wang Huan , Ding Ling , He Cong , Wan Jian-Hua , Ke Hua-Jing , Lu Nong-Hua , Li Nian-Shuang , Zhu Yin
Published: April 2024

BACKGROUND

Acute pancreatitis (AP) encompasses a spectrum of pancreatic inflammatory conditions, ranging from mild inflammation to severe pancreatic necrosis and multisystem organ failure. Given the challenges associated with obtaining human pancreatic samples, research on AP predominantly relies on animal models. In this study, we aimed to elucidate the fundamental molecular mechanisms underlying AP using various AP models.

AIM

To investigate the shared molecular changes underlying the development of AP across varying severity levels.

METHODS

AP was induced in animal models through treatment with caerulein alone or in combination with lipopolysaccharide (LPS). Additionally, using Ptf1α to drive the specific expression of the hM3 promoter in pancreatic acinar cells transgenic C57BL/6J- hM3/Ptf1α(cre) mice were administered Clozapine N-oxide to induce AP. Subsequently, we conducted RNA sequencing of pancreatic tissues and validated the expression of significantly different genes using the Gene Expression Omnibus (GEO) database.

RESULTS

Caerulein-induced AP showed severe inflammation and edema, which were exacerbated when combined with LPS and accompanied by partial pancreatic tissue necrosis. Compared with the control group, RNA sequencing analysis revealed 880 significantly differentially expressed genes in the caerulein model and 885 in the caerulein combined with the LPS model. Kyoto Encyclopedia of Genes and Genomes enrichment analysis and Gene Set Enrichment Analysis indicated substantial enrichment of the TLR and NOD -like receptor signaling pathway, TLR signaling pathway, and NF-κB signaling pathway, alongside elevated levels of apoptosis-related pathways, such as apoptosis, P53 pathway, and phagosome pathway. The significantly elevated genes in the TLR and NOD -like receptor signaling pathways, as well as in the apoptosis pathway, were validated through quantitative real-time PCR experiments in animal models. Validation from the GEO database revealed that only MYD88 concurred in both mouse pancreatic tissue and human AP peripheral blood, while TLR1 , TLR7 , RIPK3 , and OAS2 genes exhibited marked elevation in human AP. The genes TUBA1A and GADD45A played significant roles in apoptosis within human AP. The transgenic mouse model hM3/Ptf1α(cre) successfully validated significant differential genes in the TLR and NOD -like receptor signaling pathways as well as the apoptosis pathway, indicating that these pathways represent shared pathological processes in AP across different models.

CONCLUSION

The TLR and NOD receptor signaling pathways play crucial roles in the inflammatory progression of AP, notably the MYD88 gene. Apoptosis holds a central position in the necrotic processes of AP, with TUBA1A and GADD45A genes exhibiting prominence in human AP.
Tráfico de pessoas para fins trabalhistas
Authors: Guevara Ramírez Lydia
Published: April 2024

A Assembleia Geral das Nações Unidas declarou o dia 30 de julho como o Dia Mundial contra o Tráfico de Seres Humanos, com o objetivo de sensibilizar para a situação das vítimas do tráfico de seres humanos, promovendo e protegendo os seus direitos. O tráfico de seres humanos é um crime internacional contra a humanidade, que viola os direitos humanos, atacando a liberdade e a dignidade das vítimas. Afeta praticamente todos os países, seja como ponto de origem, trânsito ou destino. É chamada de escravidão do século XXI. O objetivo deste artigo é divulgar as ações realizadas em Cuba para revelar as causas e consequências das manifestações do tráfico de pessoas no local de trabalho e as políticas públicas que garantam a tolerância zero à exploração laboral de todas as pessoas, especialmente mulheres, meninas, meninos e adolescentes.
DYNAMICS OF FEMALE CRIMINALITY IN SAMARA PROVINCE IN 1872–1914
Authors: Баринова Е.П.
Published: April 2024

Уровень женской преступности является важнейшим показателем нравственного состояния общества. В статье на основе сравнительно-сопоставительного анализа статистических данных, содержащихся в отчетах губернаторов и сведений Министерства юстиции, охарактеризованы динамика и особенности женской преступности в Самарской губернии в 1872–1914 гг. Доказано, что различие форм отчетности, используемых полицейскими и судебными органами, затрудняет получение общей картины динамики женской преступности. Отмечается влияние на ее качественные и количественные характеристики множества различных факторов, в числе которых сословная принадлежность, возраст, семейное положение, образование, род занятий и профессиональная ориентация женщин. Изучение динамики преступности позволило охарактеризовать зависимость девиантного поведения от степени социального контроля за поведением личности со стороны органов власти и корпораций, в состав которых она была включена. Выделены особенности развития женской преступности в лонгитюдный период второй половины XIX – начала XXв., дана характеристика изменений ее структуры на различных этапах. Максимального уровня женская преступность в Самарской губернии достигла в 1909–1914 гг., что было обусловлено трансформацией ценностей, постепенным разрушением семейных устоев и патриархальных традиций. Доказано, что социальная и экономическая модернизация общества способствовали росту девиантного поведения женщин.

The level of female criminality is the most important indicator of the moral state of society. In the article on the basis of comparative analysis of statistical data contained in the reports of governors and data of the Ministry of Justice the dynamics and features of female crime in Samara province in 1872–1914 are characterised. It is proved that the difference in the reporting forms used by police and judicial authorities makes it difficult to obtain a general picture of the dynamics of female crime. The influence on its qualitative and quantitative characteristics of many different factors, including class affiliation, age, marital status, education, occupation and professional orientation of women is noted. The study of the dynamics of crime allowed us to characterise the dependence of deviant behaviour on the degree of social control over the behaviour of the individual by the authorities and corporations in which she was included. The peculiarities of development of female criminality in the longitudinal period of the second half of the XIX – beginning of the XX centuries are singled out, the changes in its structure at different stages are characterised. The maximum level of female crime in Samara province reached in 1909–1914, which was the transformation of values, the gradual destruction of family foundations and patriarchal traditions. It is proved that social and economic modernisation of society contributed to the growth of deviant behaviour of women. Keywords: female crime, statistical data, Samara province, governors' reports, demographic and social characteristics.
REVISITING THE IMPOSITION OF CRIMINAL PENALTIES ON MINORS
Authors: Владимиров С.В.
Published: April 2024

Статья посвящена типизации экстремизма и терроризма. Рассмотрены понятие терроризма и его опасное влияние на основы конституционного строя; права и свободы человека и гражданина; политическое, экономическое и социальное устройство государства. Отмечена важность типизации экстремизма и терроризма. Изложены классификации экстремизма и терроризма по различным основаниям. Так, по масштабу действия выделяют внутригосударственный и международный экстремизм и терроризм; в зависимости от мотивов ненависти и вражды выделяют политический, религиозный, расовый (национальный) экстремизм и терроризм; по видам применяемых средств выделяют экстремизм и терроризм массового поражения, экономический и информационный; в зависимости от количества субъектов выделяют индивидуальный, групповой и массовый экстремизм и терроризм. Определены тенденции развития современного экстремизма и терроризма. Основными направлениями их развития являются популяризация достижения политических целей посредством экстремистско-террористических действий, что указывает на международный характер, обширность применения и предельно большое количество человеческих жертв; появление и развитие новых видов экстремизма и терроризма; появление новых целей экстремизма и терроризма. Отмечено, что рассмотренные тенденции отражают современную обстановку в обществе и государстве.

The article is devoted to the extremism and terrorism typification. The concept of terrorism and its dangerous influence on the foundations of the constitutional system; human and civil rights and freedoms; political, economic and social structure of the state are considered. The importance of typification of extremism and terrorism is noted. The classifications of extremism and terrorism on various grounds are outlined. Thus, according to the scale of action, domestic and international extremism and terrorism are distinguished; depending on the motives of hatred and enmity, political, religious, racial (national) extremism and terrorism are distinguished; According to the types of means used, extremism and terrorism of mass destruction, economic and informational are distinguished; depending on the number of subjects, individual, group and mass extremism and terrorism are distinguished. Trends in the development of modern extremism and terrorism have been identified. The main directions of their development are the popularization of achieving political goals through extremist and terrorist actions, which indicates the international character, the vastness of application and the extremely large number of human victims; the emergence and development of new types of extremism and terrorism; the emergence of new goals of extremism and terrorism. It is noted that the considered trends reflect the current situation in society and the state, but are not exhaustive.
THE SPECIFICS OF THE SEARCH AND SEIZURE IN CASES INVOLVING HEALTH HARM IN PENAL INSTITUTIONS
Authors: Владимиров С.В. , Грязева Н.В.
Published: April 2024

В статье рассматриваются отдельные криминалистические и уголовно-процессуальные аспекты производства обыска и выемки по уголовным делам, связанным с причинением вреда здоровью в условиях учреждений уголовно-исполнительной системы. Анализируются принципы производства обыска и выемки и их трансформация в условиях учреждений уголовно-исполнительной системы; некоторые вопросы планирования и подготовки к обыску и выемке, в том числе в условиях противодействия расследованию со стороны спецконтингента. На основе изучения уголовных дел о преступлениях, связанных с причинением вреда здоровью и совершенных в учреждениях уголовно-исполнительной системы, выявлены недостатки производства обыска и выемки, а также некоторые закономерности их производства. Перечислены типичные способы сокрытия преступлений, связанных с причинением вреда здоровью в пенитенциарных учреждениях. Сформулированы практические рекомендации производства обыска и выемки: относительно участия понятых, привлечения специалистов, организации работы по поиску криминалистически значимых следов преступлений. Акцентировано внимание на специфике объектов, на которые нацелена поисковая деятельность следователя в ходе обыска и выемки в процессе расследования преступлений, связанных с причинением вреда здоровью в учреждениях уголовно-исполнительной системы.

The article examines certain criminalistic and criminal procedural aspects of the search and seizure in criminal cases related to harm to health in institutions of the penal enforcement system. The principles of search and seizure and their transformation in the conditions of institutions of the penal enforcement system are analyzed; some issues of planning and preparation for search and seizure, including in conditions of counteraction to the investigation by the special agent. Based on the study of criminal cases of crimes related to harm to health and committed in institutions of the penal enforcement system, the shortcomings of the search and seizure, as well as some patterns of their production, have been identified. The typical ways of concealing crimes related to harm to health in penitentiary institutions are listed. Practical recommendations for the search and seizure are formulated: regarding the participation of witnesses, the involvement of specialists, the organization of work to search for criminally significant traces of crimes. Attention is focused on the specifics of the objects targeted by the investigator's search activity during the search and seizure during the investigation of crimes related to harm to health in institutions of the penal enforcement system.