bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study on Morphological Effect of Nano WO3 Particles for Dye Sensitized Solar Cell Application
Authors: Jayakumar S. , Poongkothai J.
Published: March 2023

Tungsten oxide (WO3) nanoparticles of rod-like and spherical morphologies were synthesized using sol-gel modified Pechini’s method. The spherical morphology is achieved by optimizing precursor concentration. The synthesized WO3 nanoparticles were characterized by powder XRD for phase analysis and SEM for size and morphological analysis. It was revealed that the synthesized particles have spherical and rod-like shapes, are in the monoclinic phase and in the nano range. Dye sensitized solar cells were fabricated by incorporating WO3 nanoparticles in 0.5, 1 and 2 wt.% with anatase TiO2 nanoparticles and their photovoltaic characteristics were investigated. It was found that the incorporation of WO3 nanoparticles with nano TiO2 particles considerably enhanced the short circuit current density (Jsc) and power conversion efficiency (η). Further, it was found that WO3 nanoparticles with small size and spherical morphology have higher short circuit current density (13.27 mA cm-2) and power conversion efficiency (6.63%) compared to rod-like WO3 nanoparticles.
Preparation and Infrared Spectroscopic Studies of Fully Deuterium Oxide Replaced Analogue of Calcium Oxalate Monohydrate
Authors: Christy Alfred Antony , Sukumar Raveena , Wije Munige Shakya Sankalpani Gunasena
Published: March 2023

The present research work reports the preparation of 100% deuterium oxide replaced the analogue of calcium oxalate monohydrate (COM) for the first time. The replacement of crystalline water in COM was carried out in a water-free environment by shaking a portion of the sample of COM with a calculated amount of deuterium oxide. Several experiments were conducted to study both partially deuterium oxide replaced samples and the composition of water/deuterium oxide in the liquid phase. Reflectance spectroscopy was used in analyzing the solid and liquid samples using special sample accessories. Furthermore, a full deuterium oxide replaced sample was exposed to atmospheric water to study the exchange of deuterium oxide molecules from the solid samples with water molecules. The results show that the full deuterium oxide replaced COM can be prepared using a suitable water-free environment. The infrared spectra of these samples clearly show that the water molecules in the crystal structure were replaced by deuterium oxide molecules assuming identical positions in the crystal structure. However, the bands arising from the deuterium oxide molecules were narrower than the bands due to water molecules. The analysis of the liquid samples during the partial deuterium oxide replacement shows that the replacement of the water of crystallization by deuterium oxide is 60% after 6 h of shaking. The full deuterium oxide replaced sample exposed to atmospheric water shows that the replacement of deuterium oxide by water molecules from the vapour phase is a slow process.
Synthesis and Characterization of Membranes from Sulfonated Polystyrene Waste and TiO2 Fillers (PSS/TiO2) as Proton Exchange Membranes
Authors: Gunawan  , Wijaya R.A. , Dayanti D. , Septiyani M.D. , Rahmawati S. , Faiz M.F.
Published: March 2023

Synthesis of sulfonated membrane from polystyrene waste and TiO2 filler as proton exchange membrane has been carried out. The effect of variations in the concentration of polystyrene (10%, 15%, 20%) and the addition of TiO2 was studied. The solvothermal synthesis results of TiO2 confirmed by XRD showed the typical peaks according to standards. The membrane characterization was analyzed by FTIR, SEM-EDX and LCR meter. The success of sulfonation was evidenced by the presence of sulfonate groups at 1171.37 and 1170.67 cm–1 with degree of sulfonation (DS) of 10%, 15% and 20% PSS membranes of 32.02%, 40.03% and 48.04%, respectively. The insertion of TiO2 filler into the membrane was confirmed by SEM-EDX and its effect could increase the conductivity value (σ). The results showed that this membrane has the potential to be developed as a proton exchange membrane fuel cell.
Effect of Combination of Tween-80 with Amphiphilic Peptides on Physical Stability of Nanoemulsion Using Low-Energy Emulsification Technique
Authors: Kumar Rajeev , Hussain Shaik Abdul , Purkayastha Debopriya
Published: March 2023

The current study was investigated to replace Tween-80 with peptides in order to produce physical and microstructure stability of nanoemulsion. Oil phase (2%), Tween-80 (4%) and remaining aqueous phase were taken to form nanoemulsions. In combinations of Tween-80 and peptides three ratios (1:2, 2:1 and 1:1) were taken keeping the overall concentration 4% fixed. The particle size of nanoemulsion stabilized with Tween-80, peptides and combination of Tween-80-peptides (1:2, 1:1, 2:1) were 148.71 ± 1.48, 283.66 ± 10.17, 254.50 ± 14.77, 161.90 ± 3.67, 182.80 ± 5.37 nm, showing smallest particle size with 50% replacement of Tween-80 with peptides. The zeta potential data showed competitive adsorption between Tween-80 and peptides. The polydispersity index of Tween-80:peptides (1:1) had found to be 0.33 ± 0.01 where as Tween-80 and peptides stabilized nanoemulsion had 0.20 ± 0.01 and 0.30 ± 0.05. The changes in electrical conductivity occurred maximum in case of peptides and electrical conductivity decreased with increase in concentration of Tween-80 due to preventing mobility of ions. The storage stability of nanoemulsions were found better at 4 ºC, however Tween-80:peptides (1:1) and peptides stabilized nanoemulsion had particle size growth onwards 14 days at 37 ºC. The transmission electron microscopy (TEM) image of nanoemulsion Tween-80:peptides (1:1) showed uniform distribution of peptides in combination compared with individual peptides stabilized nanoemulsion.
Microwave Synthesis and Biological Evaluation of Coumarins Substituted Furylpyrazolylpyrazoline
Authors: Shaikh Parin V.
Published: March 2023

Some new furaylpyrazolylpyrazoline substituted coumarins were synthesized under microwave irradiation. Target compounds were obtained by cyclization of coumarin chalcones with various substituted hydrazine hydrate and arylhydrazines to give the corresponding pyrazoline by Michael addition reaction (1,4-addition on α,β-unsaturated carbonyl group). Establishment of the structure of the synthesized compounds were based on 1H NMR, 13C NMR, IR, mass spectrometry and elemental analysis data. The synthesized compounds were screened for antibacterial in vitro against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhi (bacteria) and Aspergillus niger, Candida albicans (fungi) and some of the compounds are acted as potential antimicrobials.
Aluminium Doped Cerium Oxide as an Efficient Nanophotocatalyst for the Elimination of Rhodamine B Dye Present in Water
Authors: Chidaraboyina Swathi , Nesaraj Arputharaj Samson , Arunkumar Manasai
Published: March 2023

The photodegradation efficiency of rhodamine B (RhB) dye present in water using aluminium-doped CeO2 (Ce1-xAlxO2-δ; x = 0, 0.1, 0.2, 0.3, 0.4 and 0.5) nanoparticles was studied in this work. The synthesis of nanoparticles was done by simple wet chemical precipitation route. The photochemical characteristics of Al doped CeO2 was studied by UV-visible (UV) and photoluminescence (PL) techniques. The photocatalytic removal of RhB dye was studied using the above nanomaterials as photocatalysts and the degradation efficiency was optimized by varying the pH and the concentration of dye solution under UV light. Among the samples studied, 0.02 g of sample with the composition of Ce0.50Al0.50O2-δ exhibited a higher photocatalytic degradation efficiency of 70.94% against RhB dye having concentration of 0.05 g/L at the pH of 11 under UV irradiation for 60 min at room temperature.
Simultaneous Estimation of Repaglinide and Voglibose in Newly Approved Fixed-Dose Combination by using UFLC: Application to ICH Q14 Concept and Comparative Method Greenness Assessment
Authors: Panda S.S. , Rauta P.C. , Pulusu V.S. , Sahu S. , Dash B.B.
Published: March 2023

A validated liquid chromatographic method was developed to estimate repaglinide and voglibose present in a newly approved fixed dose combination. Critical method variables such as organic proportion, pH and flow of the mobile phase were identified. The identified variables were investigated using chemometrics and effect on analyte retention and resolution was studied. The optimized chromatographic condition utilized acetonitrile: 0.01 M KH2PO4 buffer pH 3.4 (using orthophosphoric acid) (79:21%, v/v) flowing at a flow rate of 1.2 mL/min. Diode array detection was carried out at 244 nm.The new analytical method was validated as per ICH regulations and found to be linear, accurate, precise and sensitive. Both drugs were recovered to the optimum (> 99%) level. Further, method greenness was compared by using multiple tools. This developed method based on ICH Q14 concept is scientifically sound and can be applied for quality control of both the anti-diabetic drugs in their combined formulation.
A Recoverable PANI/α-Fe2O3 Nanocatalyst for Ultrasound-Assisted Knovenagel Condensation
Authors: Bora Manisha A. , Chabukswar Vasant V. , Vashishtha Manu
Published: March 2023

In this research work, a new PANI/α-Fe2O3 (PANI = polyaniline) nanocatalyst was prepared and applied to ultrasound-assisted Knoevenagel condensation reaction using ultrasound waves at ambient temperature. The ultrasound-assisted synthesis is a quick, green and efficient C–C bond formation reaction method. Many parameters of the condensation reaction were optimized, such as irradiation time, types of solvent, screening of catalyst and its amount. The results showed that the yields from the ultrasound-assisted reactions were higher than from non-irradiated responses as well as other conventional routes of synthesis. The prepared catalyst was characterized via SEM-EDS, FTIR, DLS and XRD studies. The stability and catalytic performance of the PANI/α-Fe2O3 were good and it could be reused six times without loss in catalytic activity. The dinitrile molecules were synthesized by Knoevenagel condensation and characterized by FTIR and NMR techniques. Compared to the reported work, the present protocol has numerous benefits such as economical, simplistic workup, high yields and, an environmentally gentle method with a shorter reaction time.
Antibacterial Potentiality of Isatin-Containing Hybrid Derivatives: A Review
Authors: Suvaiv  , Singh Kuldeep , Kumar Praveen , Hasan Syed Misbahul , Kushwaha Shom Prakash , Kumar Arun , Ismail Khatib Sayeed , Mujeeb Samar , Maurya Shubham Kumar , Zaidi Syed Mehdi Hasan
Published: March 2023

Antibiotics are critical in the management of a variety of bacterial infections, however, repeated infections produced by relentless bacteria are obstructing effective infection treatment and it is the most significant and vexing problem at the moment. Medicinal chemists face a difficult problem in developing appropriate lead compounds for various diseases, isatin and its hybrids would be one of them due to its versatility in many medications and its derivatives exhibit an extensive variety of structural and mechanistic properties. This review looks at the isatin hybrids that have probable antibacterial action. The structure-activity relationship (SAR) and the way of producing action are also examined in order to locate the course for the intent and expansion of isatin hybrids by means of increased efficacy, reduced toxicity and good pharmacokinetic profiles. Based on the findings, it can be inferred that 3-hydrazone, imine, spiro, oxindole, guanidino and N-alkyl, aryl, acyl substituted isatin hybrids with electronegative groups on other heterocycles have improved bactericidal activity. Furthermore, the antibacterial activity of isatin is dependent on the binding linkage, such as amide (NHCO), carbonyl (CO) or other hetero atom-containing linkers that have improved antibacterial activity. This review gives an idea and scope for the synthesis of novel isatin-containing heterocyclics with the goal of having potent bactericidal activity.
Green Synthesis and Characterization of Nickel Oxide Nanoparticle for Rhodamine-B Adsorption using Phyllanthus emblica Fruit Extract
Authors: Malini P.S. Geetha , Rani S. , Manonmani J. , Jayaprakash R.
Published: March 2023

In this work, the nanoadsorbent efficiency of nickel oxide nanoparticles (NiONPs) for the degradation of rhodamine B (RhA-B) dye was examined. The NiONPs were synthesized by green technique using NiCl2·H2O and Phyllanthus emblica fruit extract. The NiO nanoparticles were characterized using UV, FTIR, FESEM, HRTEM and TGA/DTA analysis to study the decomposition pattern, functional groups, crystalline size and elemental composition of nanoparticles. TEM analysis showed that the nanoparticles were spherical, highly crystalline, highly agglomerated and appeared as clusters of nanoparticles in the size range converted into tubular shape. The prepaed NiONPs were used for batch experiments to evaluate the adsorption capacities of the dye. The influence of various key parameters, i.e. adsorbent dosage and initial dye concentration were investigated. The extent of adsorption of RhA-B was found to be 88% at pH 6. Langmuir isotherm showed maximum monolayer adsorption with qm values from 328-465 mg/L. The kinetic investigation of RhA-B degradation followed a pseudo-second-order rate kinetics with a rate constant of 2.0495 × 10-2 mg-1 min-1. ΔGº = − 79.00 kJ/mol indicates that the adsorption is chemisorption and spontaneous.
The Role of the Human Resources Business Partner (HRBP) Manager in Dealing with Economic Crises in Organizations in the Public Sector in Israel
Authors: Qassoom Mohammad
Published: March 2023

This article sought to develop an understanding of the Human Resource Business Partner (HRBP) manager's role in addressing economic crises in Israeli public sector businesses. Understanding the HRBP's role in addressing the economic crisis in Israel has been one of the critical goals. Results have also supported the idea that HRBP managers share rather than own business strategy and vice versa(Cavusgil, Knight, & Riesenberger, 2020). The results verify that the execution of the HRBP function has been a critical aspect of integrating HR with the business at the Authority for National-Civic Service in dealing with economic crises. However, the change in focus from HRBP assistance to business partnering highlighted in this thesis also indicates that the reinvention of HRBP is typically a continual and fragmented process, both in the literature and in practice(Storey, Ulrich, & Wright, 2020). As a result, the HRBP post at the Authority for National-Civic Service comprises a high level of individualism. It is affected by professional and contextual criteria, such as seniority and the specific business unit under which it acts. Finally, the HRBPs at the Authority for National-Civic Service can reach the position of trusted advisers and perform mainly on a strategic level, even with individual and contextual variances recognized. The business partners have a crucial role in boosting overall HR performance, so continuing focus on creating and sustaining interactions with managers and HRBP professionals in other areas is encouraged(Youndt, Snell, Dean, & Lepak, 2019).
Considerations of the Optimized Protective Action Distance to Meet the Korean Protective Action Guides Following Maximum Hypothesis Accidents of Major KAERI Nuclear Facilities
Authors: Lee Goanyup , Kim Hyun Ki
Published: March 2023

Background: Korea Atomic Energy Research Institute (KAERI) operates several nuclear research facilities licensed by Nuclear Safety and Security Commission (NSSC). The emergency preparedness requirements, GSR Part 7, by International Atomic Energy Agency (IAEA) request protection strategy based on the hazard assessment that is not applied in Korea.Materials and Methods: In developing the protection strategy, it is important to consider an accident scenario and its consequence. KAERI has tried the hazard assessment based on a hypothesis accident scenario for the major nuclear facilities. During the assessment, the safety analysis report of the related facilities was reviewed, the simulation using MELCOR, MACCS2 code was implemented based on a considered accident scenario of each facility, and the international guidance was considered.Results and Discussion: The results of the optimized protective actions were 300 m evacuation and 800 m sheltering for the High-Flux Advanced Neutron Application Reactor (HANARO), the evacuation to radius 50 m, the sheltering 400 m for post-irradiation examination facility (PIEF), 100 m evacuation or sheltering for HANARO fuel fabrication plant (HFFP) facility.Conclusion: The results of the optimized protective actions and its distances for the KAERI facilities for the maximum postulated accidents were considered in establishing the emergency plan and procedures and implementing an emergency exercise for the KAERI facilities.
The Influence of Hr Information Systems, Competence, and Work Discipline on Work Productivity Post-Merger Bank Syariah Indonesia
Authors: Septianingsih Harum , Saibil Defi Insani
Published: March 2023

ABSTRACT
Research Aims: HR information systems, competencies, and work discipline are the independent variables while work productivity is the dependent variable used.
Methodology: The case studies that became the research population were employees of Bank Syariah Indonesia Mataram Pejanggik 1 Branch Office. This research is a quantitative research with saturated sampling technique used in determining the sample. The distribution of respondents obtained was 40 filled out questionnaires. Data analysis method with IBM SPSS 26 because it uses multiple linear regression analysis.
Research Findings: The results of this study were obtained   simultaneously from the three variables influencing employee work productivity. Meanwhile, if partially obtained the results of information system variables, and work discipline have a positive and significant effect on work productivity. But the competency variable partially has no positive and significant effect on employee work productivity. The results of this study are that Bank Syariah Indonesia Pejanggik 1 Branch has implemented an HR information system that is accurate and clear, as well as good work discipline, even though there are still employees who are not competent in their fields.
Analisis Persepsi Generasi Z Terhadap Investasi Berbasis ESG (Enviromental, Social, and Governance) di Jakarta Islamic Index
Authors: Azhar Jeihan Ali , Nada Cantika Putri Kadua  , Rizki Dwi Safitri
Published: March 2023

Research aims: Penelitian ini bertujuan untuk mengetahui faktor yang memengaruhi minat berinvestasi berbasis Environmental, Social, and Governance (ESG) di Indeks Jakarta Islamic Index (JII). Penelitian ini mengadopsi teori UTAUT dengan model SEM PLS.
Design/Methodology/approch: Metode pengumpulan data adalah survei menggunakan penyebaran kuesioner dengan pertanyaan tertutup. Jumlah responden dalam penelitian ini sebanyak 134 responden. Teknik pengambilan sampel menggunakan metode non-probability sampling dengan menerapkan purposive sampling. Teknik analisis data menggunakan SEM-PLS dan aplikasi SPSS 25.
Research findings: Hasil penelitian ini menunjukkan bahwa financial literacy, subjective norm, dan atittude berpengaruh signifikan terhadap minat investasi berbasis Environmental, Social, dan Governance (ESG). Namun religiusitas tidak tidak berhasil memoderasi minat gen z berinvestasi di Indeks Jakarta Islamic Index (JII).
Research limitation and implication: Implikasi dari penelitian ini diharapkan dapat menjadi masukan bagi industri pasar modal syariah untuk meningkatkan pelayanan dan langkah untuk menguatkan keuangan syariah khususnya pasar modal untuk memajukan perekonomian nasional dalam menyongsong Indonesia Emas 2045.
Overtourism in a City Destination from the Perspective of Entrepreneurs: Evidence from Wroclaw, Poland
Authors: FEDYK Wojciech , SOŁTYSIK Mariusz , RÓLCZYŃSKI Tomasz , TAHERI Babak , BORZYSZKOWSKI Jacek , OKUMUS Fevzi
Published: March 2023

This study investigates how overtourism, as perceived by entrepreneurs operating in the local tourism economy, manifests itself in a large city – Wroclaw (Poland). Data were collected via a questionnaire in November 2021. The study reveals overtourism symptoms in Wroclaw, while their influence on selected city features is not recognized by entrepreneurs as a threat. Negative and positive effects of tourism in Wroclaw are identified on the basis of research that considered (via nonprobability sampling) the opinions of entrepreneurial representatives participating in tourism organization and service from several sectors of the tourism economy. The findings presented here will help mitigate the above issues while neutralizing the threat of overtourism and its negative impacts.
Heterogeneity of phenotypic manifestations of cystic fibrosis in children and predictors of the disease severity
Authors: Skriabina K. V. , Ilchenko S. I. , Fialkovska A. O.
Published: March 2023

The aim of the study was to investigate the heterogeneity of phenotypic manifestations of cystic fibrosis (CF) in children depending on the CFTR gene mutation and to determine predictors of the disease severity for the personalization of treatment and prevention of complications.
Materials and methods. Fifty-nine children with CF, aged 1 to 18 years (mean age was 12.0 (8.5; 15.0) years), were examined. All patients underwent general clinical, genetic, laboratory and microbiological examination. Instrumental methods of examination included spirometry, chest X-ray and computed tomography, ultrasound densitometry. According to the functional effects of CFTR mutations, the patients were divided into two groups. The group with “severe” genotypes (n = 40) included patients with two class I and/or II mutations, and the group with “mild” genotypes (n = 10) included patients with at least one class IV or V mutation. Mutations were not identified in 9 patients.
Results. Analysis of the spectrum of genetic variants in the CFTR gene showed that 10 patients (20.0 %) were identified with the “mild” genotype, and 40 patients (80.0 %) with the “severe” genotype. The most common mutation was F508del predominantly in the compound heterozygous state (42.4 %). It was found that patients with the “mild” genotype were characterized by a more favorable course of the disease than patients with the “severe” genotype. No statistically significant phenotypic features of the CF course in children depending on the F508del mutation status (F508del/F508del or F508del/nonF508del) were found, except for earlier formation of pulmonary hypertension in patients with the homozygous condition (47.1% vs 16.0 %, P < 0.05).
Conclusions. Examination of the relationship between CFTR genotype and phenotype has revealed associations between CFTR mutations and lesion severity of both the digestive and bronchopulmonary systems. Identification of disease severity predictors can provide a more accurate prediction of the disease course, that will determine the patient management and prevent the development of complications.
Pharmacogenic and neurologic components of residual condition in schizophrenia
Authors: Chuhunov V. V. , Darii V. I. , Safonov D. M. , Horodokin A. D.
Published: March 2023

Aim. To systematize neuroleptic-induced and neurologic components of residual condition in schizophrenia.
Materials and methods. 100 patients of Communal Non-Profit Enterprise “Regional Clinical Institution for the Provision of Psychiatric Care” of Zaporizhzhia Regional Council with diagnosis of recurrent schizophrenia (ICD-10: F20.5) were examined.
Results. The study has found correlations between pharmacotherapy and cerebrovascular pathology with positive and negative symptoms of residual schizophrenia. Noticeable positive correlations were established between specific antipsychotic prescriptions and positive negative schizophrenia symptoms, while only minor correlations with negative symptoms were found.
Analysis of cerebrovascular pathology with positive and negative symptoms showed that most noticeable positive correlations were anterior area stroke with hallucinations.
Overall dominance of negative correlations over positive ones showed possible trend of “forced normalization” caused by cerebrovascular pathology of schizophrenia manifestations in recurrent condition, which was, however, also minor.
Conclusions. The study has found correlations between pharmacotherapy and cerebrovascular pathology with positive and negative symptoms of residual schizophrenia. The concept of “antipsychotic course experience” was introduced.
From King Hyegong to Suh Dongjin: the evolution of LGBT and homosexual rights in the Korean community, according to historiographical texts
Authors: Müller Aleksandra
Published: March 2023

Even though homosexuality and other sexual minorities have never been considered illegal by the Korean government, people identifying as non-heteronormative were and are still vastly ostracised. Furthermore, the LGBT community was and is still facing social stigmatism. What cultural conditions influenced the way non-heteronormative minorities are perceived by most South Korean society? How has the LGBT minority developed over the centuries? When did the attitudes of South Koreans change for the better? The following article covers the answers to the above-stated questions based on a particular query of texts related to the topic based on historiographic records. In the first section, the influence of the Confucian ideas of Three Fundamental Bonds and Five Constant Virtues (三綱五倫, 삼강오륜 [samgangoryun]) on the image of 'correct relationship' and the Taoist division of gender roles based on energy adversity (yin (陰, 음 [eum]) and yang (陽, 양 [yang])) will be explained. This will serve as a basis for understanding cultural opposition to same-sex relationships. The following subchapter consists of a chronological overview of the most important historical records regarding same-sex relationships. The third subchapter presents the sexual minority groups formed in the 1990s, such as Chodong Society (초동회 [chodonghoe]), Between Friends (친구사이 [chingu sai]) and Maeum 001 (마음001 [maeum gongongil]), which had the most significant impact on the development of the contemporary LGBT movement in South Korea. The last section presents current changes and problems that the South Korean LGBT society faces.
William A. Foley. 2022. A sketch grammar of Kopar. A language of New Guinea (Pacific Linguistics 667). Berlin – Boston: De Gruyter Mouton, pp. xvii + 248
Authors: Majewicz Alfred F.
Published: March 2023

Review
Does Corruption Hinder Domestic Investment in the MENA Region: Evidence from a Panel-Country Analysis
Authors: Al-Tal Raad , Al-Tarawneh Yaseen , Mahasneh Shera
Published: March 2023

This study aims to investigate the impact of different facets of corruption on domestic investment (DI) in the Middle East and North Africa (MENA) economies. The main purpose of this empirical research to assess the influence of bribes, abuse of public office and nepotism on domestic investment in 14 MENA countries over the period 2005–2022. The results of 2SLS model indicate that corruption could affect negatively on domestic investments through two channels, namely: illegal payments (bribes) and the abuse of public office for private gain. In this case, the regulators and decision makers have to formulate new strategies that aimed particularly to fight these kinds of corruption to increase domestic investment.
Existence of anti-periodic solutions for Ψ-Caputo-type fractional p-Laplacian problems via Leray--Schauder degree theory
Authors: El Mfadel Ali , Melliani Said , Elomari M’hamed
Published: March 2023

The main crux of this work is to study the existence of solutions for a certain type of nonlinear Ψ-Caputo fractional differential equations with anti-periodic boundary conditions and p-Laplacian operator. The proofs are based on the Leray–Schauder degree theory and some basic concepts of Ψ-Caputo fractional calculus.
As an application, our theoretical result has been illustrated by providing a suitable example.
Computing subdifferential limits of operators on Banach spaces
Authors: Rao T. S. S. R. K.
Published: March 2023

Let

X
,
Y

{X,Y}

be real, infinite-dimensional Banach spaces. Let

ℒ
⁢

(
X
,
Y
)

{{\mathcal{L}}(X,Y)}

be the space of bounded operators. An important aspect of understanding differentiability of the operator norm at

A
∈

ℒ
⁢

(
X
,
Y
)

{A\in{\mathcal{L}}(X,Y)}

is to estimate the limit
(which always exists)

lim

t
→

0
+

⁡

∥

A
+

t
⁢
B

∥

-

∥
A
∥

t

 

for 
⁢
B

∈

ℒ
⁢

(
X
,
Y
)

,

\lim_{t\rightarrow 0^{+}}\frac{\lVert A+tB\rVert-\lVert A\rVert}{t}\quad\text{%
for }B\in{\mathcal{L}}(X,Y),

using the values of B on the state space

S
A

=

{

τ
∈

ℒ
⁢

(
X
,
Y
)

∗

:

τ
⁢

(
A
)

=

∥
A
∥

,

∥
τ
∥

=
1

}

.

S_{A}=\bigl{\{}\tau\in{\mathcal{L}}(X,Y)^{\ast}:\tau(A)=\lVert A\rVert,\,%
\lVert\tau\rVert=1\bigr{\}}.

In this paper, we give several examples of Banach spaces, including the

ℓ
p

{\ell^{p}}

spaces
(for

1
<
p
<
∞

{1<p<\infty}

)
where a more tangible estimate is possible, under additional hypotheses on A.
We also use the notion of norm-weak upper-semi-continuity (usc, for short) of the preduality map to achieve this.
Our results also show that the operator subdifferential limit is related to the
corresponding subdifferential limit of the vectors in the range space, when

A

∗
∗

{A^{\ast\ast}}

attains its norm.
Dispersion braiding and band knots in plasmonic arrays with broken symmetries
Authors: Yin Shixiong , Alù Andrea
Published: March 2023

Periodic arrays can support highly nontrivial modal dispersion, stemming from the interplay between localized resonances of the array elements and distributed resonances supported by the lattice. Recently, intentional defects in the periodicity, i.e., broken in situ symmetries, have been attracting significant attention as a powerful degree of freedom for dispersion control. Here we explore highly nontrivial dispersion features in the resonant response of linear arrays of plasmonic particles, including the emergence of braiding and band knots caused by band folding. We show that these phenomena can be achieved within simple dipolar arrays for which we can derive closed-form expressions for the dispersion relation. These phenomena showcase powerful opportunities stemming from broken symmetries for extreme dispersion engineering, with a wide range of applications, from plasma physics to topological wave phenomena. Our theoretical model can also be generalized to higher dimensions to explore higher-order symmetries, e.g., glide symmetry and quasi-periodicity.
Complexes of a model trimeric acylphloroglucinol with a Cu2+ ion: a DFT study
Authors: Mammino Liliana
Published: March 2023

Acylphloroglucinols (ACPLs, derivatives of phloroglucinol having at least one R−C=O group) are gaining increasing attention for their pharmacological potentialities. The presence of phenol OHs in their molecules confers antioxidant properties to ACPLs. Some ACPLs have already been identified as promising antioxidants for pharmaceutical purposes. Antioxidant properties may also be useful for a variety of other applications, including industrial ones. A viable option to verify and compare the antioxidant efficacy of compounds considers their ability to form complexes with a metal ion and reduce its charge. The present work considers a model structure maintaining all the identifying features of trimeric ACPLs (ACPLs containing three phloroglucinol moieties linked by methylene bridges) and studies the complexes of representative conformers with a Cu2+ ion, with the ion binding in turn to each of the available binding sites. Two series of calculations are performed at the DFT/B3LYP/6-31+G(d,p) level, without and with the Grimme’s D3 dispersion correction: the former series enables meaningful comparisons with previous calculations of complexes of other ACPLs, and the latter series is meant to evaluate the effect of taking dispersion into account on the estimation of the complexes’ properties. The results show that the Cu2+ ion is reduced to Cu+ ion. The molecule–ion interaction energy and the charge and spin density on the ion are comparable with those of complexes of known antioxidant ACPLs.
LIQ HD (Lick Instance Quantifier Home Cage Device): An Open-Source Tool for Recording Undisturbed Two-Bottle Drinking Behavior in a Home Cage Environment
Authors: Petersen Nicholas , Adank Danielle N. , Raghavan Ritika , Winder Danny G. , Doyle Marie A.
Published: March 2023

Investigation of rodent drinking behavior has provided insight into drivers of thirst, circadian rhythms, anhedonia, and drug and ethanol consumption. Traditional methods of recording fluid intake involve weighing bottles, which is cumbersome and lacks temporal resolution. Several open-source devices have been designed to improve drink monitoring, particularly for two-bottle choice tasks. However, beam-break sensors lack the ability to detect individual licks for bout microstructure analysis. Thus, we designed LIQ HD (Lick Instance Quantifier Home cage Device) with the goal of using capacitive sensors to increase accuracy and analyze lick microstructure, building a device compatible with ventilated home cages, increasing scale with prolonged undisturbed recordings, and creating a design that is easy to build and use with an intuitive touchscreen graphical user interface. The system tracks two-bottle choice licking behavior in up to 18 rodent cages, or 36 single bottles, on a minute-to-minute timescale controlled by a single Arduino microcontroller. The data are logged to a single SD card, allowing for efficient downstream analysis. LIQ HD accuracy was validated with sucrose, quinine, and ethanol two-bottle choice tasks. The system measures preference over time and changes in bout microstructure, with undisturbed recordings tested up to 7 d. All designs and software are open-source to allow other researchers to build on the system and adapt LIQ HD to their animal home cages.
LncRNA LITATS1 suppresses TGF‐β‐induced EMT and cancer cell plasticity by potentiating TβRI degradation
Authors: Fan Chuannan , Wang Qian , Kuipers Thomas B , Cats Davy , Iyengar Prasanna Vasudevan , Hagenaars Sophie C , Mesker Wilma E , Devilee Peter , Tollenaar Rob A E M , Mei Hailiang , ten Dijke Peter
Published: March 2023

Epithelial cells acquire mesenchymal phenotypes through epithelial‐mesenchymal transition (EMT) during cancer progression. However, how epithelial cells retain their epithelial traits and prevent malignant transformation is not well understood. Here, we report that the long noncoding RNA LITATS1 (LINC01137, ZC3H12A‐DT) is an epithelial gatekeeper in normal epithelial cells and inhibits EMT in breast and non‐small cell lung cancer cells. Transcriptome analysis identified LITATS1 as a TGF‐β target gene. LITATS1 expression is reduced in lung adenocarcinoma tissues compared with adjacent normal tissues and correlates with a favorable prognosis in breast and non‐small cell lung cancer patients. LITATS1 depletion promotes TGF‐β‐induced EMT, migration, and extravasation in cancer cells. Unbiased pathway analysis demonstrated that LITATS1 knockdown potently and selectively potentiates TGF‐β/SMAD signaling. Mechanistically, LITATS1 enhances the polyubiquitination and proteasomal degradation of TGF‐β type I receptor (TβRI). LITATS1 interacts with TβRI and the E3 ligase SMURF2, promoting the cytoplasmic retention of SMURF2. Our findings highlight a protective function of LITATS1 in epithelial integrity maintenance through the attenuation of TGF‐β/SMAD signaling and EMT.
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface
Authors: Li Mingyi , Zheng Jing , Luo Dong , Xu Kai , Sheng Ren , MacDonald Bryan T , He Xi , Zhang Xinjun
Published: March 2023

The membrane‐tethered protease Tiki antagonizes Wnt3a signaling by cleaving and inactivating Wnt3a in Wnt‐producing cells. Tiki also functions in Wnt‐receiving cells to antagonize Wnt signaling by an unknown mechanism. Here, we demonstrate that Tiki inhibition of Wnt signaling at the cell surface requires Frizzled (FZD) receptors. Tiki associates with the Wnt‐FZD complex and cleaves the N‐terminus of Wnt3a or Wnt5a, preventing the Wnt‐FZD complex from recruiting and activating the coreceptor LRP6 or ROR1/2 without affecting Wnt‐FZD complex stability. Intriguingly, we demonstrate that the N‐terminus of Wnt3a is required for Wnt3a binding to LRP6 and activating β‐catenin signaling, while the N‐terminus of Wnt5a is dispensable for recruiting and phosphorylating ROR1/2. Both Tiki enzymatic activity and its association with the Wnt‐FZD complex contribute to its inhibitory function on Wnt5a. Our study uncovers the mechanism by which Tiki antagonizes Wnt signaling at the cell surface and reveals a negative role of FZDs in Wnt signaling by acting as Tiki cofactors. Our findings also reveal an unexpected role of the Wnt3a N‐terminus in the engagement of the coreceptor LRP6.
Healthy And Unhealthy Lifestyles As Factors Of Occupational Burnout In Obstetrics And Gynecology Physicians
Authors: Kuzmin Mikhail Yu. , Tyumentseva Darya P. , Marianian Anait Yu.
Published: March 2023

This article investigates healthy and unhealthy lifestyles and its components (physical activity, drinking alcohol, consumption of caffeinated products, tobacco use) as factors of occupational burnout in obstetrics and gynecology physicians. Material and Methods. A total of 132 physicians and nurses from the different clinics of Irkutsk were surveyed. We used Maslach Burnout Inventory (MBI), SF-12, and Godin Leisure-Time Exercise Questionnaire. Results: Differences in healthy and unhealthy lifestyles between physicians and nurses employed in obstetrics and gynecology, with or without a high burnout, were revealed. According to the obtained results, the frequency of alcohol consumption was directly related to burnout. In study subjects engaged in low and moderate physical activity, burnout occurred briefly or rarely. The differences became more pronounced when we excluded physicians and nurses with poor physical health from consideration, because they did not exercise much. According to the results of logistic regression, the probability of burnout and reduced level of quality of life among physicians and nurses increased with a bigger family size, lower work experience, and less time spent on moderate physical activity. Conclusion: Healthy and unhealthy lifestyles can cause healthcare employee burnout. Physicians and nurses with a high burnout consumed stronger alcohol and spent less time in moderate physical activity.
THE MEDIATING EFFECT OF HAPPINESS AT WORKPLACE ON THE RELATIONSHIP BETWEEN HYBRID WORK MODEL AND EMPLOYEE RETENTION IN IT INDUSTRY
Authors: R. Santiago Antony Selvi  , Vandana Madhavkumar
Published: March 2023

The word “Great Resignation” is shaking up many organizations across different sectors in the world. The Covid-19 pandemic significantly changed the employees’ views on their careers. During the Covid-19 pandemic, organizations mostly used the flexible work arrangements like work from home (WFH) or remote work (RW) and hybrid work model (HWM) to run their business activities ensuring safety of employees. Work from home option and hybrid work is changing the work dynamics. It has become a significant reason for the employees especially women employees to continue their employment as they can also continue care-giving at home and do remote work. It has been reported that they were quitting their jobs when organizations insisted on them being physically present in the office. The purpose of this study is to determine the impact of hybrid work model on happiness at work and employee retention and also to find  out does the happiness at work mediate on the relationship between hybrid work and employee retention. Hence, the empirical study was conducted among employees working in IT companies. The sample size was 200 and the collected data was analyzed using SPSS and AMOS. Hybrid work model was found  to provide employees the space and flexibility to manage their professional and personal life and also increase their happiness at work. Happiness at work was found to positively impact retention of employees and mediates on the relationship between hybrid work model and employee retention. In the situation of a high shortage of skilled employees, the hybrid work model could be the most effective method to attract and retain skilled employees, since it influences the employee’s intention to stay or quit their job. The findings of the study will be help organizations to design the modern workplace with futuristic development and to retain talents.
The Professional Level and its Impact on Muscle Mechanical and Functional Performance in Costa Rican Soccer Players
Authors: Rojas-Valverde Daniel , Martínez-Guardado Ismael , Esquivel-Rodríguez María J. , Sánchez-Ureña Braulio , Gutiérrez-Vargas Juan Carlos , Gutiérrez-Vargas Randall
Published: March 2023

This study aimed to compare the mechanical and functional muscle performance of three different competitive soccer teams of the Costa Rica professional league (U17, Pro A, and Pro B). Age 20.09 ± 4.32 years old, weight body mass 70.85 ± 7.45 kg, height 174.56 ± 4.97 cm; body fat percentage 13.9 ± 5.06 %; lean body mass 57.90 ± 4.88 kg; lean body mass right lower limb 10.11 ± 0.87 kg; lean body mass left lower limb 10.09 ± 0.92 kg. The variables assessed were muscle time of contraction, muscle radial displacement, delay time, squat jump, and countermovement jump. The devices used were dual ray absorptiometry, tensiomyography, and jump platform. There were differences in weight, body mass, and body fat % (Pro A< U17 U17). There were no significant differences in muscle time of contraction, delay time, or radial deformation. The knowledge of differences in both muscle functional and mechanical performance could lead to new training and recovery methods and protocols considering the player’s professional levels.
La femme dans la spirale de la violence
Authors: Borloz Soto Virginia
Published: March 2023

Dans cet article on veut montrer que la littérature de l’écrivaine algérienne Assia Djebar se meut dans un contexte de violence qui se manifeste dans le texte au moyen d’actes linguistiques historiquement comprobables et qui visent la femme comme la cible de la violence masculine. En tenant compte de la notion de pluriculturalité propre de la francophonie et de l’importance de l’écriture pour la femme marquée par une double appartenance qui remet aux notions de plurilinguisme, poliphonie, visibilité de la femme, dominationmasculine, ambiguité, ironie et transgression, on fait le parcours et l’analyse des pratique génératrices de violence. Prenant comme exemple un de ses romans et au moyen de l’analyse d’actes linguistiques qui rendent compte du statut de la femme algérienne, l’influence de la religion, la domination masculine, ainsi que la construction de l’identité, on constate la violence historiquement exercée contre la femme algérienne en particulier et contre la femme en général et qui fait que, dans l’actualité et un peu partout dans le monde, la femme se meut dans la spirale de la violence.
Cuba en Repertorio Americano, entre nacionalismo y vanguardia
Authors: Vázquez Marlene
Published: March 2023

Joaquín García Monge promoted intercultual dialogue in Latin America from Costa Rica, where the work of Martí and the intellectual production of Cuba had an important place, as well as the avant-garde youth that came to life the legacy of the Cuban hero.
Apuntes sobre el antiimperialismo y el proimperialismo de Haya de la Torre en Repertorio Americano
Authors: Barrera Rivera Dan Abner
Published: March 2023

This article is a critical approach to the Peruvian politician Víctor Raúl Haya de la Torre, based on his writings published in the Costa Rican journal Repertorio Americano between November 1924 and August 1955. We found 73 texts by the author and 29 texts by another authors. Due to Repertorio, Haya became internationally known as one of the most representative voices of anti-imperialism. But this position is only one face of the Peruvian politician.We discovered in these texts his radical transformation in favor of imperialism. This is a less known change that we are interested in analyze.
Effects of ethanol pretreatment on dissolution and structural changes of lignin from steam-exploded wheat straw
Authors: Pan Cheng , Liu Zhong , Yao Lan , Yang Haitao , Hui Lanfeng
Published: March 2023

Pretreatment of steam-exploded wheat straw by ethanol has been used to dissolve lignin. Different pretreatment conditions were explored by varying reaction temperature, time, and the ratio of solid to liquid to determine that the rate of dissolution was approximately 51.6%. The examination of structural changes in LP (lignin from ethanol pretreatment pulp) showed that the conjugated carbonyl/carboxyl of lignin was partly destroyed during ethanol pretreatment and alkali extraction process. The content of total hydroxyl groups was increased with increasing ethanol pretreatment. Higher intensities of the aromatic ring in LP and LL (lignin from black liquor) fractions compared to that of weak pretreatment conditions indicated that some extent of lignin condensation occurred during the ethanol pretreatment. The ratios of S/G in LP were higher than in LL and removal of the methoxyl groups happened during the ethanol pretreatment process, and this led to changes in proportions of lignin structural units.
Baltic Dry Index Estimation With NARX Neural Network Model
Authors: Kılınç Gamze , Kocabıyık Turan , Karaatlı Meltem
Published: March 2023

BDI is a global trade indicator followed by those interested in maritime trade. But it has volatility, seasonality, and uncertain cyclicality. For this reason, in this study, the BDI has been estimated to provide preliminary information to those interested in maritime trade. NARX Neural Network which performs successfully in complex and nonlinear real-life problems is used. In addition, the NARX neural network model has not been found in a previous study used for BDI estimation. Eleven independent variables are used in this study, what increases the predictive power. Independent variables are Bloomberg Commodities Index (BCOM), Twitter-Based Economic Uncertainty Index (TEU), Twitter-Based Market Uncertainty Index (TMU), S&P 500 Index, MSCI World Index, €/$ Parity, VIX (CBOE), US 10-Year Bond Yield (%), Brent Oil (USD/Barrel), Economic Uncertainty Index and World Trade Volume (USD Billion). The Twitter-Based Economic Uncertainty Index (TEU) and Twitter-Based Market Uncertainty Index (TMU), which were not used before in BDI estimation studies, were included in the analysis and contributed to the literature. The data set contains daily data for the period 9.07.2012–31.08.2020. 11-day estimate values covering 1.09.2020–15.09.2020 are calculated. MAPE, MAE and RMSE performance criteria were calculated for the estimation values. Value of MAPE (2.96%), value of MAE (36.6%) and value of RMSE (46.68) were obtained. As a result, the estimate values were compared with the actual values.
Paauglio politrauma žemdirbystės pramonėje: klinikinio atvejo analizė
Authors: Bagdonaitė Kamilė , Sugintaitė Emilija , Dekerytė Inga , Lukošiūtė-Urbonienė Aušra , Kilda Artūras
Published: March 2023

Polytrauma is a condition when a patient has sustained multiple injuries, which can lead to disability or death. While the agriculture industry is growing, the number of polytrauma patients in children is increasing as well. It is high-energy traumas when it is important to immediately assess injuries and life-threatening conditions and to start trauma protocols guided treatment. In this article, we present a case of a 17-year-old boy who suffered extensive injuries caused by a straw pellets machine. We discussed the importance of prehospital care, multidisciplinary team involvement, and treatment methods.