bluuebunny/crossref_metadata_2025 huggingface dataset:
Hoikusho sebagai Faktor Utama Work Life Balance dalam Anime Gakuen Babysitters
Authors: Natania Alifia , Endah Srimulyani Nunuk
Published: September 2023

Work Life Balance (WLB) adalah salah satu isu krusial di Jepang dan di berbagai belahan dunia. WLB adalah keseimbangan antara kehidupan pribadi dengan pekerjaan. Penelitian ini bertujuan untuk mendeskripsikan bagaimana “Morinomiya hoikushisetsu” sebagai salah satu alternatif bentuk Tempat Pengasuhan Anak (hoikusho) menjadi pilar utama dalam harmonisasi WLB para staff, guru pengajar dan murid SMA dalam anime Gakuen Babysitters. Anime ini menceritakan tentang kehidupan kakak beradik yang menjadi yatim piatu akibat kecelakaan pesawat terbang yang terjadi pada orang tua mereka sehingga sang kakak harus merawat adiknya sendirian sembari bersekolah di SMA. Metodologi yang digunakan dalam penelitian ini adalah deskriptif kualitatif, dengan menggunakan teori representasi oleh Stuart Hall. Dari hasil analisis dapat diketahui bahwa hoikusho pada sekolah Morinomiya telah berhasil memadukan berbagai kepentingan para para guru, staff, dan siswa untuk menitipkan anak atau adik mereka dengan biaya yang sangat rendah karena sistem sukarelawan yang dibangun seperti kegiatan ekstra kurikuler sekolah. Di sisi lain, institusi sekolah sebagai inisiator juga mendapatkan keuntungan karena staff mereka merasa tenang dan nyaman bekerja/belajar karena anak atau adik mereka berada dalam pengasuhan yang aman dan terjangkau dari segi jarak dan finansial. Sebagai kesimpulan, anime Gakuen Babysitters ini menggambarkan pentingnya Tempat Pengasuhan Anak sebagai syarat terwujudnya WLB bagi orang-orang yang harus berperan ganda. Ekstra kurikuler pengasuhan anak dalam anime ini juga menembus batas kemusykilan kurangnya hoikusho di Jepang.
Arctic cinema: from horror through dramas and thrillers To Action movies and fiction (Part I)
Authors: Zonn I. S.
Published: September 2023

The article considers a number of genres of Arctic films in the world cinema. Among them, some of the most common are horror films (horror), thrillers (part I), dramas, science fiction and action films (part II). The socio-political climate of the times determined the evolution of genres and influenced their semantic content and structure. Their formation and production flow has a calendar milestone. In the second half of the twentieth century, after the end of the Great Patriotic War, a cold war began between two blocs of states with different socio-economic systems led by the USSR and the USA. It was she who strengthened the militaristic role of the Arctic not only in the military-industrial sphere, but also in the cinematographic one. Hollywood, as part of the political and ideological machine of the United States, immediately responded with its films. The screen was politicized in the general range of Cold War sentiments. Conducting atomic tests, the appearance of the atomic bomb in the USA in 1945 and in the USSR in 1949, “flying saucers” from space, noted in 1947, brought to life horror films, science fiction and drama. The heroes of the films were monsters that descended to earth from outer space or rose from the depths of the ocean, all kinds of mechanical and biological monsters awakened by nuclear tests. In parallel, western cinema constructed models of anti-Soviet orientation. The purpose of the films was to amuse and captivate the viewer into an illusory world and at the same time, to shock, amaze, terrify and excite him with scientific or pseudoscientific fiction. This goal remains the main one for most fantastic horror and thrillers. Some of them preached violence, cruelty, conflict, degradation of the human personality. Aggressiveness, programmed in the person himself, is increasingly, manifested in Arctic thrillers and action film.
The PANDAS/PANS disorders. Is it time for more allergist-immunologists to get involved?
Authors: Bellanti Joseph A.
Published: September 2023

Background: The pediatric autoimmune neurologic disorders associated with streptococcal infections (PANDAS) comprise a group of patients who, after infection with group A β-hemolytic streptococci (GAS), exhibit a spectrum of neuropsychiatric symptoms that include obsessive
thoughts, compulsive behaviors, tics, hyperactivity, inattention, and mild choreiform movements. More recently, a group of patients with a symptom complex similar to PANDAS without evidence of streptococcal etiology was given the acronym pediatric acute-onset neuropsychiatric syndrome (PANS).
Despite more than several decades of study and increasing numbers of patients being identified with PANDAS and PANS, there are ongoing controversies, which range from disagreements about specific pathogenetic mechanisms to whether these entities actually exist. Objective: The
purpose of this report was to examine the current body of evidence that deals with the relationship(s) of immunologic host responses to infection and putative immunologic mechanisms involved in the pathogenesis of these disorders, to evaluate the effectiveness of anti-inflammatory and immunomodulatory
therapies with intravenous immunoglobulin (IVIG), and to consider the extent to which allergist/immunologists might be involved in their management. Methods: An extensive literature review was conducted in medical literature data bases by applying terms such as PANDAS,
PAN, autoimmune encephalitis, neuroinflammation, and autoimmune obsessive-compulsive disorders. Results: PANDAS and its later iterative form, PANS, continue to challenge clinicians, patients, and their families. Although the precise reason why these disorders develop remains
unknown, both are considered to have an autoimmune basis related to the production of antibodies directed at antigens of the putative causative infectious disease agents that are cross-reactive with antigenic epitopes on selected brain nuclei, which lead to the neuroinflammatory sequelae responsible
for the neuropsychiatric symptoms of these conditions, a phenomenon referred to as molecular mimicry. Conclusion: The PANDAS/PANS disorders are a continuing burden for growing numbers of patients, health-care providers, and the global health-care systems, and are a particular
challenge for the allergist/immunologist who is increasingly being called upon for their management. Because of the importance of immunologic factors in the pathogenesis and treatment of these conditions with anti-inflammatory and immune-modulating treatments, the allergist/immunologist is
well poised to offer consultative care.
Diagnosis of eosinophilic esophagitis in patients with dysphagia during the Coronavirus Disease 2019 (COVID-19) pandemic
Authors: Brennan Jennifer , Yamada Kelsey , Al-Shaikhly Taha , Ghaffari Gisoo
Published: September 2023

Background: The coronavirus disease 2019 (COVID-19) pandemic posed restrictions to many standard practices. Dysphagia is a common presentation of eosinophilic esophagitis (EoE) in adults, and biopsy via esophagogastroduodenoscopy (EGD) is required for diagnosis. We hypothesized
that a diagnosis of EoE has declined during the pandemic. Objective: To investigate whether the COVID-19 pandemic influenced the likelihood of an EGD and an EoE diagnosis in patients with dysphagia. Methods: In this retrospective matched cohort study,
we used the TriNetX US Collaborative Network to identify adult patients who presented with dysphagia to the emergency department (ED) during the year of and the year preceding the pandemic. Patients with a previous EoE diagnosis were excluded. The two cohorts were balanced for demographics,
gastroesophageal reflux disease (GERD) diagnosis, obesity, H2 blockers and proton-pump inhibitors use, anemia, smoking, and alcohol use. The proportion of patients who received an EGD, and an EoE and a GERD diagnosis were contrasted up to 90 days from ED evaluation. Results:
We identified 16,942 adult patients during the pandemic, and 16,942 adult patients the year preceding the pandemic who presented to the ED with a concern of dysphagia. During the 30-day follow-up period, no significant difference was observed in the proportion of patients who received
an EGD during the pandemic versus the prepandemic period at 1, 7, and 30 days from ED evaluation. The proportion of patients who received an EoE diagnosis was not different, but slightly more patients received a GERD diagnosis during the pandemic versus prepandemic that was evident by day
30 (31.2% versus 30%; p ≤ 0.05). Conclusion: Our results revealed that the COVID-19 pandemic did not significantly impact diagnostic EGD and an EoE diagnosis.
Development of anaphylaxis upon oral food challenge and drug provocation tests in pediatric patients
Authors: Turgay Yagmur Irem , Kulhas Celik Ilknur , Yilmaz Topal Ozge , Toyran Muge , Civelek Ersoy , Dibek Misirlioglu Emine
Published: September 2023

Background:The drug provocation test (DPT) and the oral food challenge (OFC) are considered as the criterion standard for the diagnosis of drug hypersensitivity reactions and food allergy. Severe allergic reactions may develop during these tests.Objective:To evaluate the frequency and features of anaphylaxis in pediatric patients undergoing OFCs and DPTs.Method:OFCs and DPTs performed in an open method in the pediatric allergy clinic of our institution between January 2014 and January 2021 were reviewed retrospectively. The characteristics of anaphylaxis that developed during these tests were evaluated.Results:A total of 3631 OFCs and/or DPTs were performed on 2588 pediatric patients. Reactions were recorded in 317 challenges (8.7%), including 42 (1.2%) in the form of anaphylaxis. Of the patients with anaphylaxis, 31 developed anaphylaxis during OFC and 11 during DPT. Anaphylaxis during OFCs was mostly triggered by yogurt (n = 8), hen’s egg (n = 6), baked milk (n = 5), and baked egg (n = 4). Cases with anaphylaxis during DPT were recorded mostly with ibuprofen (54.5% [n = 6]). All patients who developed anaphylaxis during OFC had cutaneous manifestations, and 90.3% had respiratory symptoms. Gastrointestinal involvement was present in 32.3% of the patients. During DPT, cutaneous manifestations were observed in 90.9% in the patients who developed anaphylaxis and the respiratory tract was involved in 81.8%. In terms of concomitant allergic diseases, 51.6% of the patients who developed anaphylaxis during OFC had atopic dermatitis and 38.7% had asthma. All the patients with anaphylaxis triggered by nonsteroidal anti-inflammatory drug DPT had asthma. Of the anaphylaxis, 54.8% were mild, 35.7% were moderate, and 9.5% were severe. Severe anaphylaxis was recorded with baked milk (n = 2), baked egg and trimethoprim-sulfamethoxazole (n = 1, each). The patients did not require intensive care, and no death occurred.Conclusion:Anaphylaxis may develop during OFCs and DPTs. These tests should be carried out by experienced allergists in an appropriate setting where emergency equipment and medications, including epinephrine, are readily available.
Prevalence of food allergy in the Chinese population: A systematic review and meta-analysis of population-based studies
Authors: Feng Hua , Luo Nan , Xiong Xiujuan , Wu Yongning
Published: September 2023

Background: The prevalence of food allergy is increasing and varies among different populations. Study on the food allergy prevalence is very limited in China. Objective: To assess the prevalence of food allergy in the Chinese population by using systematic
evaluation and meta-analysis. Methods: A literature search for population-based epidemiologic study on food allergy in China was conducted in several Chinese and English medical literature data bases. Pooled prevalence data and 95% confidence intervals were calculated to
estimate the prevalence of food allergy in China. Subgroup analyses were performed to eliminate and explain the heterogeneity, and also to obtain the prevalence of pooled food allergy in different populations. Results: The overall food allergy prevalence ranged from 4.0%
to 8.2%. Subgroup analysis showed a trend of overall increase of food allergy, which varied between 4.4% and 9.9%; The common allergic foods were determined to be mango, shrimp, egg, milk, and crab, with the prevalence of 1.9%, 1.5%, 1.4%, 1.3%, 1.3%, respectively; There is a lack of epidemiologic
studies on food allergy in some regions and the overall prevalence of food allergy varied from region to region in China. Conclusion: This study revealed that the prevalence of food allergy in the Chinese population ranged from 4.0% to 8.2%; Food allergy prevalence varied
by gender, age, and region. This study highlighted the need for collaborative studies of food allergy with the same rational methods to minimize potential bias caused by methods and techniques. Findings of this study may provide baseline data and scientific reference for improving policies
on prevention and control of food allergy.
Lingüística antes y ahora
Authors: Mahecha Bermúdez Miguel Ángel , Arboleda Toro Rubén David
Published: September 2023

A mediados del siglo XX, se había alcanzado un consenso de trabajo en la comunidad lingüística, basado en los grandes logros de los años precedentes.
La lingüística sincrónica se había establecido como una ciencia, una ciencia "taxonómica", con procedimientos sofisticados de análisis de datos. La ciencia taxonómica tiene sus límites. Nunca se había preguntado "¿por qué?". Había llegado el momento de buscar teorías explicativas, utilizando los conocimientos proporcionados por la teoría de la computación y los estudios de profundidad explicativa. Ese esfuerzo se convirtió en la empresa generativa dentro del marco biolingüístico. Las tensiones surgieron rápidamente: los elementos de las teorías explicativas (gramáticas generativas) estaban mucho más allá del alcance de los procedimientos taxonómicos. El principio estructuralista de que el lenguaje es una cuestión de entrenamiento y hábito, extendido por analogía, era insostenible. De manera más general, la actitud de "prácticamente todo se sabe" se convirtió en "casi nada se entiende", un fenómeno familiar en la historia de la ciencia, una era nueva y emocionante para una disciplina floreciente.
The role of selective serotonin re-uptake inhibitors in themanagement of premature ejaculation
Authors: I. Abass Al-Janabi Yasir
Published: September 2023

A prospective, randomized, placebo-conlrolled study was designed to investigate the efticacy and side effects of the selective serotonin re-uptake inhibitor, fluoxetine hydrochloride, on postponing ejaculation in patients with premature ejaculation (PE). A total of 55 men with PE were scheduled to begin this study, but 5 of them have been dropped out for unknown reason, so tbc study was completed with a total number of 50 patients. The ages of these patients (who experienced primary premature ejaculation (lifelong rapid ejaculation)) ranging between 19 to 65 years. The patients were asked to detennine the time in seconds between vaginal penet.ration and ejaculation (latency time), by using a clock for four weeks before starting the trcatment,and a baseline mean ejaculatory latency time was measured. Then the patients were given either flouxetine hydrochloride or placebo for aditiomal 8 weeks. All patients were interviewed before and 8 weeks after beginning the treatment.Baseline mean ejaculatory latency time was 60.6 s; 20 mg/day of lluoxetine increased it to 199.3 s, while in patient using placebo it was 68. 15 s (p < 0.001). This resulted in significantly greater sexual satisfaction for men: 73% (p < 0.001). Generally. fluoxetine was well tolerated and there were no major side effects. None of the patients discontinued thempy due to adverse effects. Fluoxetinae hydrochloride may be regarded as a safe and effective option in the treatment of premature ejaculation.
Five Days azithromycin is more efficient than teo DaysErythromycin for the Treatment of pertussis
Authors: D. Moohy Alosy Baha
Published: September 2023

Whooping cough (pertussis) is a highly contagious caused by Bordetella pertussis. During the last decade three Bordetella pertussis isolates have been found to be resistant to erythromycin, the azithromycin are used for treatment of pertussis. Sixty Child as 31 (5-day group) and 29 (10-day group) with pertussis in private clinic were evaluated for more efficiency of a 3-day course azithromycin in compares to a 10-day course erythromycin therapy. Treatment outcomes were stand on rates of bacteriological cure. Participants were randomized to receive 5 Days azithromycin (10 mg/kg/d) once a day or 10 Days Erythromycin 40 -30mgkg/ d in 4 divided doses, Bacteriological persistence did not happened for azithromycin ( 0% ) But for erythromycin ( one =3.44 %). Bacteriological failures occurred with azithromycin treatment (one =322%)while in Erythromycin (two ~~ =7.40 %) the estimates of bacterial cure were elevated for azithromyein 96.77% in compares for erythromycin 93.10% the bacterial cure rate time was 16.48 days for azithromycin less than for erythromycin 24.2625 days. The Variance in clinical manifestation duration for azithromycin 36.6 days less than for erythromycin 47.5 days for that our study recommended that 5-day azithromycin is more efficient than 10-day erythromycin in the treatment of pertussis in children.
Evaluation of serum ceruloplasmin, copper, iron and Vit.C levels inWomen using oral contraceptive pills in Tikrit city
Authors: A.Abed Saifaldin , R.Mahmood Ayhan , Riffat Sarhat Entedhar
Published: September 2023

Oral contraceptive steroids are used by an estimated 60 to 70 million women worldwide. Over the past 20 years there have been both case reports and clinical studies on the topic of drug interactions with these agents. The use of oral contraceptives has been consistently associated with decreased levels of the activity of many enzymes, and Vitamin C. The main transporter of copper, a2-globulin ceruloplasmin which is a multifunctional enzyme. The present study was conducted in Family planning in Tikrit Teaching Hospital in Tikrit province, Serum ceruloplasmin, copper, vitamin C, and iron levels were estimated in 54 women who were using oral contraceptives for at least I year. The mean age of women was (32.08 years vs. 27.04 years of control). The serum level of ceruloplasmin (Cp) as antioxidant protein was significantly high in comparison to control group (mean 40.5 mg/dl vs. 33.28 mg/dl, Pof serum copper in women were using contraceptive (17.03 J.!MIL) is significantly higher (Pvitamin C values in women using contraceptives were significantly lower than control group (P<0.05), the mean of vitamin C value was 3.452 ~-tM/L vs. 6.534 ~-tM/L of control. The mean value of serum iron in women were using contraception (8.642 ~tM/L) which is less significantly (P(17.603 ~-tM/L).
Prevalence of hypocalcemia among thalassemic patients registered inibn al-balady hospital
Authors: Ali Hasan Waseem , Khider Shaymaa , Hasan Dhary Al-Jumaily Ali
Published: September 2023

The objective of this study is to through light on the prevalence of hypocalcaemia in thalassemic patients registered in Ibn Al-balady Hospital (Thalassemic Centre) Baghdad- Iraq four hundred patients selected with thalassemia major were included in the study, randomly selected throughout October, 2001. They are subjected to serum study for calcium phosphorus and alkaline phosphatase. Twenty patients x-rayed for bones only no facilities for studying serum ferritin, parathyroid hormone and densometry for bones. It was found that hypocalcaemia is prevalent in eighty seven patients out of 400 and more prevalent among age group 10 years and above
serum Levels of sodium and Potassium in Patientswith Asthma on Salbutamol Therapy
Authors: S. Ahmed Salam , O. Al-janabi Hassna , A. Zbaar Sami
Published: September 2023

A total of 150 patients with asthma on salbutamol therapy were included in this study along with 90 apparently healthy adult person ( control group) were investigated for the measurements of serum sodium and potassium levels. All patients and controls were fasting when sampleds Sodium and potassium serum levels have been performed by using flame photometer. All patients showed a normal serum sodium (mean 139.8 mmol/L)while the majority (73.4%) of the patients showed hypokalemia (mean 3.1 mmol/L)when compared to control. This study showed that salbutamol have no deteriorated effect on sodium, while it may reduce potassium levels in the majority of patients.
Clinico-epidemiological study cf skin lyarts among patientsattending Tikrit teaching hospital
Authors: Najm Khansaa , Hamed Mazin , Abdul-Aziz Ahmed
Published: September 2023

Back ground : Warts are benign epidermal neoplasms that are caused by human papilloma virus (HPVs). Warts are transmitted by touch; it may occur on adjacent toes ("kissing lesions"), or at sites of trauma at the hands, in periungual regions as a result of nail biting, and on plantar . surface. There are different clinical types as Common warts (Verruca vulgaris) begin as smooth, flesh-coloured papules and evolve into dome-shaped, gray-brown, hyperkeratotic growths with black dots on the surface ( thrombosed capillaries).The hands are the most commonly involved areas, but they may be found on any skin surface. Patients and methods: One hundred and twenty four (124) patients with warts were encountered in the outpatient clinic of dermatology at Tikrit Teaching Hospital from October 2008 to May 2009.Patients were examined by dermatologists and medical history was taken using special questionnaire. Results: from 124 patients , 68 (54.8%) were males. Preschool and primary school children were the most age group affected (41 %). Most frequent of wart cases were from urban (62%). The hands was the most frequent site in the body affected (24%). The most frequent wart type was a common wart (54.8%). Regarding the associated diseases atopic dermatitis was the most frequent (12%). Conclusion: The most frequent wart type was a common wart (54.8%)and The hands was the most frequent site in the body affected(24%).
Study of some haematological and biochemical variables inchildren with iron- deficiency anaemia in Erbil-citv
Authors: A. Maulood Kalthum
Published: September 2023

This study was carried out in pediatric out patients ward of Rapareen hospital in Erbil city, which included 45 children with iron deficiency anaemia (IDA), males and females, whose age range is betweenl-5 years old, with 45 healthy children at same age and sex considerd as control group, to determine the hematological and biochemical variables. The results indicate a significant decrease (p < 0.01) in haemoglobin, packed cell volume and red blood cell count in children with iron deficiency aanemia (IDA) when compared with control. White blood cell count, lymphocyte number, platelet count and red distribution width were increased significantly (p < 0.01) in children with IDA when compared with control. No significant differences observed in neutrophil number in children with IDA and control. Mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration decreased significantly (p < 0.01) in children with IDA when compared with control. Significant decrease (p < 0.01) noticed in serum iron and transferrin saturation in children with IDA when compared with control. While total iron binding capacity increased significantly (p < 0.01) in children with IDA when compared with control. Serum creatinine, urea, aspartate transamminase and alanine
Synthesis, Characterization and Study the Biological Activity ofnew Derivatives of 1,3- orazepine containing 1,2,4-Triazoloe ring
Authors: A. Yass Iman , A. Jabar Salwa , H. Jumaa Fawzi
Published: September 2023

Compound [1] is prepared from Esterificition of 4-Nitro benzoic acid. It has been reacted with hydrazine to get compound [2]. 3,5-bis (4-Nitro phenyl)-4-amino -1,2,4-triazole [3] has been synthesized by melting of 4-Nitro benzoic acid hydrizide to cretin temperature. The new series of Schiff bases [4a-f] have been syntheised by reacting compound [3] with different benzaldehydes., These derivatives shows ring closer reaction with phathalic anhydride to obtain 1.3- Oxazepine derivatives [Sa-f]. The syntheised compound were characterized by (IR.UV) spectra, melting points the above reaction were followed by TLC. The biological activities are studied against four different kinds of bacteria .
Relationship between malondialdehyde activity (MDA) &Lipid Profile in Diabetic Patients
Authors: Salih Hamad Mahde , Jasim Khalaf Salim , Riffat Sarhat Entedhar
Published: September 2023

The current investigation was designed to seek for the relationship of malondialdehyde (MDA) with the parameters of serum lipid profile in diabetes mellitus. To achieve this purpose, 55 diabetics (l I IDDM patients and 44 NIDDM patients) and 25 age matched healthy subjects were enrolled. lt was found that significant (P<0.001) elevations of MDA, S.Tc, S.Tg, LDl-cholesterol and VLDLtriglycerides in both types of diabetics when compared with those of the healthy individuals.The correlation analysis established marked conelation of MDA with S.Tc, STg, and LDl-cholesterol levels in two types of diabetics while VLDLtriglycerides demonstrated obvious correlation with MDA in IDDM. The result pointed out the interrelation ships of MDA with serum lipid profile in diabetes mellitus.
comparative study between Juvenile and adult psoriaticarthropathy in rnosul area
Authors: F. Al-jumaily Abdullah
Published: September 2023

Psoriasis is anon-infectious,chronic disease of the skin. Arthritis associated in various age groups. This study used to evaluates difference between juvenile and adult psoriatic arthropathy at Mosul city, Mosul teaching hospital during the period of 1 st Jan. till 3o1h of June 2002. 115 patients with psoriasis participated in this study, 80 of them more than 16 years old consist of 41.9% male and 58.1% female with mean age ±SD = 38.6 ± 15.3, while other 35 patients less than 16 years old consist of 60% male and 40% female with mean age± SD = 9.2 (4-16). Arthritis associated, followed or antedated skin lesions, in 20% of them nails were affected, only 20% of juvenile patients and about 80.5% of adult patients were complaint of morning stiffness and only I 0.5% of adult patients developed ocular involvements in form of iritis. Family association of psoriasis and or psoriatic arthritis were presents in both juvenile and adult patients with psoriatic arthritis.
Effect of hormonal contraceptives on serum ceruloplasmin,copper, and Vit.C levels in Tikrit city
Authors: R. Sarhat Entedhar
Published: September 2023

Oral contraceptive steroids are used by an estimated 60 to 70 million women worldwide. Over the past 20 years there have been both case repofts and clinical studies on the topic of drug interactions with these agents. The use of oral contraceptives has been consistently associated with decreased levels of the activity of many enzymeq and Vitamin C. The main transporler of copper, u2-globulin ceruloplasmin which is a multifunctional enzyme. The present study was conducted in Family pianning in Tikrit Teaching Hospital in Tikrit province, Serum ceruloplasmin, copper, vitamin c, and iron levels were estimated in 40 women who were using oral contraceptives for at least 1 year and 40 women who were using copper T(lntrauterine contraceptive device). The mean age of women was (33.08 years).For1y non- contraceptive users participated in the study as a control group. They were drawn from the same population and matched for age with the contraceptive-users group. The serum level of ceruloplasmin (Cp) as antioxidant protein was significantly higher in women were using oral contraceptive than control group (60+0.16 mg/dl vs. 36.5+0.96 mg/dl, P<0.05) while the difference between the serum (Cp) in control and women uiing copper T is statically non significant P<0.05, also mean of serum copper in women were using contraceptive (18+0.612 pM/L) is significantly higher (P<0.01) than the mean of control (11.2+0.474 pMiL), while the difference between the serum copper in control and women r-rsing copper T is statically non significant(p<0.01). On ine other hand the serum vitamin C values in women using oral contraceptives and copper T(5.57+0.02 , 6+0.031 pM/L respectively) were significantly lower than conirol group(10.73+ 0.09 pM/L, P<0.05.
Preparation of2 - thio ether - 1, 3, 4- oxadiuzole derivatives used asantibacterial and antifungus agents
Authors: M-Daher Al-joubory Abed- , S- Hamad Ayad -
Published: September 2023

bs tract Isonicotinic acid, o-hydroxy benzoic acid, p-chlorobenzoic acid p-nitro benmteacid and 0-acetyl benzoic acid, have ben csterificated with absolute ethanol wing Fisher method to prepare compounds [I-5J. -Most compounds %vac converted to acid hydra idef; [6-10] by the reaction with hydrazine hydrate. The avid hydrazides were allowed to react with carbon disulfide (CS2) in the presence of potassium hydroxide and ethanol to pmduce 2-substituted 1, 3, 4- oxadia7nic -5-thiol 111-15]. Thio ether derivatives as two groups (16-20) and (21-25) respectively have been prepared by the reaction between compounds 111-15] and alkyl or aryl halide, (p-bromn bcnzyl bromide and 2.4- dinitrochlurubenzene) respectively. The prepared compounds Were identified by FI_LR melting point and I WAS used to support the structure of the compounds 2-(4-chloropheny1)-5-(2,4- dini trophcny I thio)- 1 ,4-oxad iazo le and 2-(2,4-d initropheny I dtio)-3-(4-nitrophenyl)- I ,3,4- oxadiszole which can be uazd as anti bactaial and anti fungus agents
Biochemical changes in the serum of pregnant women in the thirdtrimester
Authors: Ahmed Salih Nadia
Published: September 2023

The current study was designed to verify the implication of pregnancy in the induction of serum lipid and lipoprotein changes in pregnant women . To achicve this aim ,50 pregnants and 50 age matched healthy non pregnant women {control group) were enrolled. Serum Iron, Hb, cholesterol . TIBC triglyceride, HDL — cholesterol . LDL- cholesterol ,VLDL- triglyceride concentration were measured in all subjects. Significant (P<0.0) increases were found in the levels of serum TIBC, cholesterol, triglyceride. LDL and VLDL in the pregnant women of third trimesters when compared with those of the control group. HDL levels were found to be significantly (P<0.0) elevated in pergnants of the third trimesters with those of the control group. Significant (P<0.0) decreases were found in the levels of serum iron and Hb in the pregnant women when compared with control group.
Effects of Spanwise Spacing on the Interaction of Tandem Pitching Hydrofoils
Authors: Lee David S. , Hrynuk John T. , Moored Keith W.
Published: September 2023

The interaction between a pair of tandem in-line oscillating hydrofoils is presented. The hydrofoils undergo sinusoidal pitching about their leading edges with a fixed Strouhal number of [Formula: see text] and a Reynolds number of 10,000. The streamwise spacing, spanwise spacing, and phase offset between the hydrofoils are varied. Force measurements are employed to investigate changes in thrust, lift, spanwise force, power consumption, and propulsive efficiency. A method to mitigate confounding factors from connecting rod drag is employed using streamlined fairings. Near and far streamwise spacing regions are identified with a transition occurring near 0.875 chord lengths downstream. Decreasing streamwise spacing in the far region causes a rise in the maximum power consumption of the follower hydrofoil. Decreasing streamwise spacing in the near region results in an opposite trend, with a sharp drop in maximum average power consumption by the follower. An empirical model for power consumption of the follower is developed. Increased spanwise spacing is found to weaken the interaction between the hydrofoils, driving them toward their isolated performance. This phenomenon is related to the spanwise contraction of the wake shed by the leader and is a function of the overlap of the wake region impacting the follower.
Computational Fluid Dynamics Analysis of Jet-Ullage Interactions During Microgravity Mixing
Authors: Kartuzova Olga , Kassemi Mohammad
Published: September 2023

Forced jet mixing with and without cooling has long been proposed for active pressure control of cryogenic tanks in microgravity. In this paper, a three-dimensional two-phase computational fluid dynamics (CFD) model is presented that was developed to capture the intricate dynamic interaction between a forced liquid jet and the ullage interface under weightlessness conditions. The CFD model is validated against the microgravity results of the Tank Pressure Control Experiment. The volume-of-fluid method is used to capture the ullage deformation as well as movement in the jet mixing simulations of the microgravity experiment. Two different initial ullage positions are considered, and computational results for the jet–ullage interaction are compared with a still-image sequence captured from real-time video of the experiment. Parametric simulations over a range of jet Weber numbers indicate four distinct jet–ullage interaction modes from nonpenetrating to fully penetrating, which are corroborated experimentally. Qualitative comparisons also provide good agreement between CFD predictions and experimental results with regard to the main features of the ullage dynamics, such as movement, deformation, and jet penetration during microgravity mixing.
Le modèle de la théorie de l’activité pour le design : un outil à explorer pour la recherche-projet
Authors: Zahedi Mithra , Tessier Virginie
Published: September 2023

La pratique et la recherche en design entretiennent des écarts qui tendent à freiner leur enrichissement mutuel. La présente recherche vise à partager une initiative de recherche explorant la théorie de l’activité et l’étude du design. Cette initiative a permis de démontrer la pertinence d’un tel cadre théorique pour structurer et enrichir les différentes étapes d’une recherche, autant pour la collecte de données que pour l’analyse des résultats. Au fil des recherches, nous avons modifié le modèle classique de la théorie de l’activité en l’adaptant aux activités du designer. En particulier, un créneau de recherche a été développé en support à l’apprentissage basé sur la réflexion-sur-l’action. Plusieurs équipes d’étudiants en design, via diverses initiatives, ont été invitées à collecter des données de concert avec leur propre processus de projet en utilisant un gabarit basé sur le modèle de la théorie de l’activité adapté pour le design. L’article conclut par une réflexion sur la valeur de la théorie pour la pratique et la recherche en design en plus des bénéfices pour le contexte pédagogique.
Mechanochemical Synthesis of Non-Solvated Dialkylalumanyl Anion and Solid-State-Characterization Using Crystallo-graphic Analysis and X-ray Photoelectron Spectroscopy
Authors: Kurumada Satoshi , Yamanashi Ryotaro , Sugita Kengo , Kubota Koji , Ito Hajime , Ikemoto Satoru , Chen Chaoqi , Moriyama Takumi , Muratsugu Satoshi , Tada Mizuki , Koitaya Takanori , Ozaki Taisuke , Yamashita Makoto
Published: September 2023

A non-solvated alkyl-substituted Al(I) anion dimer was synthesized by a reduction of haloalumane precursor using a mechanochemical method. The crystallographic and theo-retical analysis revealed its structure and electronic proper-ties. Experimental and theoretical XPS analysis of the di-mer with reference compounds revealed the low oxidation state of Al(I) anions. It should be emphasized that the ex-perimentally obtained XPS binding energies were repro-duced by delta SCF calculations and were linearly correlat-ed with NPA charges and 2p orbital energies.
EPR Spin Trapping of Nucleophilic and Radical Reactions at Colloidal Metal Chalcogenide Quantum Dot Surfaces
Authors: Aschendorf Caroline , Degbevi Mawuli , Prather Keaton , Tsui Emily
Published: September 2023

The possible participation of colloidal semiconductor nanocrystal quantum dot (QD) surfaces in QD-mediated photocatalytic reactions is an important factor that distinguishes QDs from other photosensitizers (e.g. noble metal complexes or organic dyes). Here, we probe nucleophilic and radical reactivity of surface sulfides and selenides of metal chalcogenide (CdSe, CdS, ZnSe, and PbS) QDs using various chemical reactions and NMR spectroscopy. Additionally, the high sensitivity of EPR spectroscopy is adapted to study these surface-centered reactions through the use of spin traps like 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) under photoexcitation and thermal conditions. We demonstrate that DMPO likely adds to CdSe QD surfaces under thermal conditions by a nucleophilic mechanism in which the surface chalcogenides add to the double bond, followed by further oxidation of the surface-bound product. In contrast, CdS QDs more readily form surface sulfur-centered radicals that can perform reactions including alkene isomerization. These results indicate that QD surfaces should be an important consideration for the design of photocatalysis beyond simply tuning QD semiconductor band gaps.
A coming of age for many-body methods: Achieving consensus with experiments for CO on MgO
Authors: Shi Benjamin X. , Zen Andrea , Kapil Venkat , Nagy Péter R. , Grüneis Andreas , Michaelides Angelos
Published: September 2023

The adsorption energy of a molecule onto the surface of a material underpins a wide array of applications, spanning heterogeneous catalysis, gas storage and many more. It is the key quantity where experimental measurements and theoretical calculations meet, with agreement being necessary for reliable predictions of reaction rates and mechanisms. The prototypical molecule-surface system is CO adsorbed on MgO, but despite intense scrutiny from theory and experiment, there is still no consensus on its adsorption energy. In particular, the large cost of accurate many-body methods makes reaching converged theoretical estimates difficult, generating a wide range of values. In this work, we address this challenge, leveraging the latest advances in diffusion Monte Carlo (DMC) and coupled cluster theory [CCSD(T)], to obtain accurate predictions for CO on MgO. These reliable theoretical estimates allow us to evaluate the inconsistencies in published temperature programmed desorption experiments, revealing that they arise from variations in employed pre-exponential factors. Utilizing this insight, we derive new experimental estimates of the (electronic) adsorption energy with a (more) precise pre-exponential factor. As a culmination of all this effort, we are able to reach consensus between multiple theoretical calculations and multiple experiments for the first time. In addition, we show that our recently developed cluster-based CCSD(T) approach provides a low cost route towards achieving accurate adsorption energies. This sets the stage for affordable and reliable theoretical predictions of reaction mechanisms and rates to guide the realization of new catalysts and gas storage materials.
Consistent Density Functional Theory-Based Description of Ion Hydration Through Density-Corrected Many-Body Representations
Authors: Palos Etienne , Caruso Alessandro , Paesani Francesco
Published: September 2023

Delocalization error constrains the accuracy of density functional theory (DFT) in describing molecular interactions in ion–water systems. Using Na+ and Cl− in water as model systems, we calculate the effects of delocalization error in the SCAN functional for describing ion–water and water–water interactions in hydrated ions, and demonstrate that density-corrected SCAN (DC-SCAN) predicts n-body and interaction energies with an accuracy approaching coupled cluster theory. The performance of DC-SCAN is size-consistent, maintaining an accurate description of molecular in- teractions well beyond the first solvation shell. Molecular dynamics simulations at ambient conditions with MB-SCAN(DC) potentials, derived from the many-body expansion, predict the solvation structure of Na+ and Cl− in quantitative agreement with reference data, while simultaneously reproducing the structure of liquid water. Beyond rationalizing the accuracy of density-corrected models of ion hydration, our findings suggest that our unified density-corrected many-body formalism holds great promise for efficient DFT-based simulations of condensed-phase systems with chemical accuracy.
Modeling lithium plating onset on porous graphite elec- trodes under fast charging with hierarchical multiphase porous electrode theory
Authors: Lian Huada , Bazant Martin
Published: September 2023

Lithium plating during fast charging of porous graphite electrodes in lithium-ion batteries accelerates degradation and raises safety concerns. Predicting lithium plating is challenging due to the close redox potentials of lithium reduction and intercalation, obscured by the dynamic resistance originated from the interplay of multiphase behavior and hierarchical pore structures. To resolve dynamic resistance of realistic porous graphite electrodes, we introduce a model of porous secondary graphite particle to the multiphse porous electrode theory(MPET) using nonequilibrium thermodynamics and method of volume averaging. Our hierarchical multiphase porous electrode theory is examined against experiments with varying fast charging conditions and capacities. With all parameters estimated from independent sources, our model quantitatively agrees with measured cell voltages , and, more importantly, experimentally determined plating onset from 2C to 6C. Spatial and temporal lithiation dynamics in porous graphite electrodes are unveiled theoretically, reproducing key features including idle graphite particles observed experimentally.
Electrocatalytic Ammonia Oxidation with a Tailored Molecular Catalyst Heterogenized via Surface Host-Guest Complexation
Authors: Roithmeyer Helena , Sévery Laurent , Moehl Thomas , Spingler Bernhard , Blacque Olivier , Fox Thomas , lannuzzi Marcella , Tilley David
Published: September 2023

Macrocyclic host molecules bound to electrode sur-faces enable the complexation of catalytically active guests for mo-lecular heterogeneous catalysis. We present a surface-anchored host-guest complex with the ability to electrochemically oxidize ammonia in both organic and aqueous solutions. With an adamantyl motif as the binding group on the backbone of the molecular catalyst [Ru(bpy-NMe2)(tpada)(Cl)](PF6) (1) (where bpy-NMe2 is 4,4’-bis(dimethylamino)-2,2’-bipyridyl, tpada is 4'-(adamantan-1-yl)-2,2':6',2''-terpyridine), high binding constants with β-cyclodextrin were observed in solution (in dmso-d6: D2O (7:3), K11 = 1581 ± 95 M-1). The strong binding affinities also transferred to a mesoporous ITO (mITO) surface functionalized with a phosphonated derivative of β-cyclodextrin. The newly designed catalyst (1) was compared to the previously reported naphthyl-substituted catalyst [Ru(bpy-NMe2)(tpnp)(Cl)](PF6) (2) (where tpnp is 4'-(naph-thalene-2-yl)-2,2':6',2''-terpyridine) for its stability during catalysis. Despite the insulating nature of the adamantyl substituent serving as the binding group, the stronger binding of this unit to the host functionalized electrode and the resulting shorter distance between the catalytic active center and the surface led to better performance and higher stability. Both guests are able to oxidize ammonia in both organic and aqueous solutions and the host-an-chored electrode can be refunctionalized multiple times (>3) following loss of the catalytic activity, without a re-duction in performance. Guest 1 exhibits significantly higher stability in comparison to guest 2 towards basic con-ditions, which often constitutes a challenge for anchored molecular systems. Ammonia oxidation in water led to the selective formation of NO3- with faradaic efficiencies of up to 98%.
Made in Spain: La “No Historia” de las Consolas Españolas
Authors: Mora-Cantallops Marçal
Published: September 2023

Avanzar hacia la construcción de una historia completa de los videojuegos españoles (y, por tanto, de la historia local) implica no sólo investigar los videojuegos producidos, sino también las consolas o máquinas diseñadas y fabricadas en España. No hacerlo supone dejar de lado aspectos muy relevantes que son clave para entender no sólo la construcción de la industria del videojuego sino también cómo se distribuyeron y comercializaron, así como para contextualizar los diferentes periodos históricos. Por ello, este proyecto pretende recopilar la información existente y avanzar en la creación de una base de datos contrastada dedicada a las consolas españolas para que futuras investigaciones puedan aprovecharla como punto de partida para abordar el resto de las cuestiones que se derivan de su creación. Así, se identifican alrededor de cincuenta máquinas que definen la primera lista exhaustiva de consolas fabricadas en España, así como múltiples cuestiones que surgen tras el examen inicial del corpus de artefactos.
Una mirada a la Oscuridad: La Estética Ludoficcional desde la Dificultad No-Mecánica
Authors: Terrasa-Torres Mateo
Published: September 2023

La dificultad está históricamente ligada al videojuego. Pero habitualmente queda tan solo apuntada como un reto diseñado para tentar las aptitudes manuales y cognitivas del jugador y hacerlo fracasar en caso de carecer del nivel exigido. Esta mirada a la dificultad es demasiado simplista para referirse a un mecanismo puramente experiencial, por lo tanto, personal, que está atravesado por múltiples factores inciertos. La dificultad pertenece al ámbito de la estética. Entonces, con una aproximación menos constreñida, la dificultad en el videojuego puede describirse como una resistencia al avance, compresión y acceso al texto ludoficcional que provoca algún tipo de sufrimiento al jugador que quiere aprehenderlo, en consonancia con el sentimiento de lo sublime o la paradoja del arte doloroso. Esta perspectiva descubre nuevas vías por las que puede discurrir la dificultad en el videojuego. Algunas de ellas, se alejan de los caminos del discurso dominante del reto mecánico. Esto es, hay formas de dificultad no-mecánicas articuladas por la narrativa, los temas tratados, la atmósfera, los afectos, la ética, la profundidad textual o la poética. Desde una perspectiva que imbrica la dimensión mecánica y ficcional del videojuego y la performativa del jugador, en este artículo exploramos estas formas ludoficcionales de dificultad nomecánica para ampliar el marco de pensamiento en torno a tan discutido concepto y así redirigirlo hacia terrenos más expresivos.
Herding Behaviour in Investors: A Study of Tadawul Financial Market
Authors: Yafouz Marwan , Yet Chu Ei
Published: September 2023

Purpose: The study investigates herding behaviour in the Tadawul stock exchange based on daily data between the years 1999 to 2019 .

 

Theoretical framework: Existence of uncertain situations affect the confidence level of the investor. This leads to investors changing their approach from rational to behavioural wherein they prefer to follow the judgements of others, thus engaging in herding behaviour. Several factors such as institutional investment,  external factors and  fundamental factors impact herding behaviour.

 

Methodology: The study uses OLS regression approach and accounts for the various factors such as institutional investment (percentage ownership in a stock, institutional ownership type, nationality) , external factors (global financial crisis, political instability, oil market volatility) and fundamental factors (P/E ratio, Share Turnover, Market Capitalization, Market Liquidity).

 

Findings: The empirical results indicate that herding is not present during the period of study. External factors and fundamental factors do not significantly impact the Cross-Sectional Absolute Deviation (CSAD) and there is no evidence of herding when accounting for these variables. However, CSAD is significantly impacted with the percentage of institutional investment, ownership and the nationality of institutional investors and there is evidence of herding when accounting for these variables.

 

Research Implications: As further scope the study proposes that the length of the time period may affect the findings and more robust analysis can be conducted by structural break models to understand the relative significance of the factors that may lead to herding during different time periods.

 

Originality: Institutional investment related factors have a significant impact on Herding behaviour of investors in the Tadawul stock exchange.