bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and Evolutionary Profile of Patients with Rheumatic Valvulopathy Operated Versus Not Operated in Chad
Authors: Narcisse Doune
Published: February 2024

Introduction: The aim of this study was to describe the clinical and evolutionary profile of patients with rheumatic valvulopathy, operated versus non-operated in Chad. Patient and methods: This was a prospective, multicenter cohort study carried out in the cardiology departments of the National Reference University Hospital Centre, cardiology Department, Renaissance University Hospital Center, and Bon Samaritain University Hospital, of N’Djamena city. It was spread over a six-year period, from January 1, 2015, to December 31, 2020. Were included in the study, all patients who had been seen on an outpatient basis and/or hospitalized for rheumatic valvular disease in the aforementioned in the aforementioned during the study period. The clinical and evolutionary characteristics of operated patients were compared with those of non-operated patients using, as required, Pearson’s chi2 test, Fisher’s exact test or Student’s t-test. The threshold of statistical significance was p<0.05. Results: A total of 80 patients (22%) had undergone surgery out of the 364 included. Valve replacement by mechanical prosthesis accounted for 77% of procedures, and valve plasty for 45%. The mean age of operated patients was 33 vs. 31 for non-operated patients (p=not significant NS). Female gender was found in 57% of operated patients vs. 52% of non-operated patients (p=NS). Dyspnea on exertion was present on admission in 65% of operated patients vs. 82% of non-operated patients (p<0.001). LVEF in operated patients was 61% vs 59% in non-operated patients (p=NS), mean LV end-diastolic diameter was 53.2 mm vs. 54.7 mm (p=NS) and PAPs were 43 mmHg vs 54 mmHg (p=0.0001). During follow-up, 36% of operated patients vs. 47% of non-operated patients had a hemodynamic complication (p=0.07), 12% of operated patients had a thromboembolic complication vs. 5% of non-operated patients (p=0.01), 13% of operated patients had atrial fibrillation vs. 15% of non-operated patients (p=0.12). Ten (10) deaths (12%) were recorded among operated patient’s vs 28 deaths (10%) among non-operated patients (p=NS). Conclusion: Morbidity and mortality in patients with rheumatic valvular disease remain high, even in patients undergoing surgery. even in patients who have undergone surgery. While there is a need to make surgery accessible to as many patients as possible, good therapeutic education and improvement of the patient's care pathway are essential. Those are the keys to effective, safe care.
Clinical study types and guidance for their correct post-pandemic interpretation
Authors: Martínez-Sellés Manuel , Prieto-Valiente Luis
Published: February 2024

Randomized clinical trials (RCTs) are key to the advancement of medicine and microbiology, but they are not the only option. Observational studies provide information on long-term efficacy and safety, are less expensive, allow the study of rare events, and obtain information more quickly than RCTs. On the other hand, they are more vulnerable to confounding factors. Prospective exploratory pilot studies share many aspects with RCTs but are not subject to supervision by external commissions or mandatory registration. Multitesting can pervert the balance of publications in favor of the desired effect. Bonferroni’s reasoning shows that if 10 studies are performed with an ineffective antibiotic, the probability that at least one will show P <0.05 might be 40%. Scenarios in which there is intensive pressure to perform research, such as the recent pandemic, might result in many research teams trying to study the effect of an antimicrobial. Even if the drug has no efficacy, if 100 research teams conduct a study to assess its usefulness, it might be virtually certain that at least one will get a P value <0.05. If the other studies (with P >0.05) are not published, the scientific commu nity would consider that there is strong evidence in favor of its usefulness. In conclusion, RCTs are a very good source of clinical information, but are not the only one. The systematic registration of all research can and should be applied to all types of clinical studies.
APPROACH TO THE TREATMENT AND PREVENTION OF COVID-19: VIRUS-SPECIFIC NUTRACEUTICALS AND PLANT EXTRACTS
Authors: Kurchenko Andrii , Mankivska Olha , Fedoruk Halyna , Kurchenko Kostiantyn
Published: February 2024

Objective. To conduct an analysis of current sources of literature on clinical symptoms in patients with the COVID-19 coronavirus, and to confirm that some nutraceuticals and plant compounds derived from plant extracts can be used in the treatment of COVID-19.

Results and discussion. Evidence of the antiviral potential of plant compounds is emerging. Curcumin has antiviral activity against a wide range of viruses, including influenza virus, adenovirus, hepatitis, human papillomavirus (HPV), human immunodeficiency virus (HIV), herpes simplex virus-2 (HSV-2), and Zika viruses. Baicalin and baicalein have been shown to inhibit SARS-CoV in vitro, and scutellarin can bind to the ACE2 receptor to prevent viral invasion. Resveratrol inhibits SARS-CoV-2 replication, reducing cytotoxicity. Melatonin interacts with CD147, the cellular receptor of SARS-CoV-2, which diffuses into cell walls, especially into erythrocytes and endothelium. Glycyrrhizin has demonstrated potential therapeutic benefit in COVID-19 infections through multiple mechanisms. Quercetin exhibits potent immunomodulatory properties by suppressing the expression of several pro-inflammatory cytokines and signalling pathways. Interferons are able to suppress the replication of SARS-type coronaviruses, so they may be useful in the treatment of COVID-19.

Conclusions. Despite the lack of clinical data, evidence from the literature suggests that some nutraceuticals and plant compounds derived from plant extracts may be used to treat COVID-19. However, the clinical evidence provided is still inconclusive and controversies exist. Given these factors, randomized controlled trials are needed to help combat the COVID-19 pandemic.
Left atrium stress echocardiography: correlation between left atrial volume, function, and B-lines at rest and during stress
Authors: Prota Costantina , Cortigiani Lauro , Campagnano Ettore , Wierzbowska-Drabik Karina , Kasprzak Jaroslaw , Colonna Paolo , Merli Elisa , Manganelli Fiore , Gaibazzi Nicola , D’Andrea Antonello , Cerracchio Emma , Meola Laura , Citro Rodolfo , Villari Bruno , Ciampi Quirino
Published: February 2024

Aim: Left atrial volume index (LAVI), left atrial reservoir function through left atrial reservoir strain (LASr), and B-lines in lung ultrasound serve as supplementary indicators of left ventricular filling pressures. This study analyzes the interrelation between LAVI, LASr, and B-lines in both resting and peak vasodilator stress.
Methods: Dipyridamole stress echocardiography (SE) was conducted on 252 individuals (180 males, 71%, age 65 years ± 10 years) with chronic coronary syndromes. LAVI was quantified using the biplane disk summation method; LASr was obtained using 2-dimensional speckle tracking echocardiography; B-lines were evaluated through a simplified 4-site scan in the third intercostal space during lung ultrasound.
Results: During SE, a reduction in LAVI (26 ml/m2 ± 14 ml/m2 vs. 24 ml/m2 ± 12 ml/m2, P < 0.001) and an increase in LASr from rest (33% ± 8% vs. 38% ± 10%, P < 0.001) were respectively observed from rest to stress. B-lines were increased significantly during SE, from 19 (7.5%) to 29 (11.5%), P < 0.001. A substantial, inverse linear correlation was identified between LAVI and LASr both at rest (r = –0.301, P < 0.001) and peak stress (r = –0.279, P < 0.001). At group analysis, peak B-lines showed a direct correlation with peak LAVI (r = 0.151, P = 0.017) and an inverse correlation with peak LASr (r = –0.234, P < 0.001). In individual assessments, 9.7% (20/207) of patients displayed stress B-lines with normal LAVI and preserved LASr, while 20% (9/45) exhibited stress B-lines with abnormalities in both LAVI and LASr.
Conclusions: Vasodilator SE with combined left atrial and volume assessment, related to pulmonary congestion, is feasible with a high success rate. Pulmonary congestion is more frequent with dilated left atrium with reduced atrial contractile reserve (ClinicalTrials.gov identifier: NCT030.49995; NCT050.81115).
Monthly and Seasonal Variation of Cloud Cover, Humidity and Rainfall in Lagos, Nigeria
Authors: Akinwumi Sayo A. , Ayo-Akanbi Olaoluwa A. , Omotosho Temidayo V. , Mastorakis Nikos. E.
Published: February 2024

The study of atmospheric variables such as cloud cover, humidity, and rainfall is needed to forecast/predict the weather to enhance policies implemented by the government concerning agriculture, water resources, and other relevant industries in Lagos State (6.45°N, 3.39°E), Southwest Nigeria. There is a need to ascertain the variability in cloud cover with other meteorological parameters in Lagos State which is fastgrowing with a total land mass of 1,171.28 square kilometers. Eleven years (2011-2021) ground data obtained from Visual Crossing a leading provider of weather data were analyzed on a monthly and seasonal basis using statistical tools. The results show that there is a significant rise in the extent of cloud cover in Lagos during July to September, with September being the peak month due to about sixty-three percent (63%) of the sky being cloudy in September. However, there is the minimum amount of cloud cover observed between December and February, with January being the least month about forty-one percent (41%) of the sky cloud-covered in the average year. Lagos experiences a yearly average humidity of 83.5% from June to October, peaks in September (87.88%), while the lowest value (77.26%) occurs in January. The annual average rainfall accumulation for the eleven (11) years is recorded to be 1611.30 mm. In June, September, and October, the rainfall rate is recorded to be very high with values that range between 242.53 mm, 227.25 mm, and 233.86 mm respectively, while December and January is observed to record the lowest accumulation of rainfall with values that ranges between 27.26 mm & 27.97 mm respectively. Finally, the comparison of the linear regression trend and the estimated Pearson correlation coefficient reveals a substantial, positive relationship exists between cloud cover and humidity, although cloud cover has a minor influence on rainfall. According to the study’s findings, it is advised that rainfall awareness programs be expanded and that government policies relating to agriculture, water resources, and other relevant sectors take into account the rising nature of rainfall in recent years.
Compressing the Geospatial Data of Testing Grounds
Authors: Mitsiukhin Anatol
Published: February 2024

The paper discusses an algorithm for obtaining the compressed spatial images of testing grounds, which are described by attribute data. The attributive representations of data make it possible to use the hardware and software resources of geographical information systems (GIS) more economically. The objects, that can be presented by a boundary, are considered as the observable ones. The efficiency of the testing ground description is achieved by representing all its areas by boundaries, encoding the boundaries using the Freeman code, and applying the entropy encoding at the last stage of image processing. At the same time, the compressed set of attributive data can be unpacked into the original image with almost no recovery errors or with acceptable accuracy, but not below the limit set by the specification. The theoretical principles of the method are illustrated by the example of processing the segmented image of the contour. The comparative assessment of the efficiency of compression of the combined method under consideration and that of the entropy encoding method is presented.
Wind Statistical Characterization in Mendoza Province. Argentina.
Authors: Dematte Rodolfo , Raso Ernesto Gandolfo , Huespe Josefina , Rebaza Arles Gil , Frassinelli Mercedes , Anzoise Esteban
Published: February 2024

In the following work, an analysis of the wind power of Mendoza Province is proposed, with the objective of its characterization and designing maps of average wind speeds. The data analyzed belongs to the wind and speed direction in the period from 1981 to 2020. The source of the information is the POWER project (Prediction Of Worldwide Energy Resources) open access database, from NASA (National Aeronautics and Space Administration). For data processing, descriptive statistical analysis was performed and the data were plotted by Kriging interpolation, which is based on the analysis of the geostatistical structure of variation of the variable to establish its behavior in space. As a result, a series of monthly maps were obtained plotting the average wind speeds for the Mendoza Province, thus characterizing the wind resource.
Investigation of Artificial Intelligence Algorithms for MPPT of Solar Photovoltaic System
Authors: Abu El-Sebah Mohamed I. , Eissa Aly M. , El-Khatib Mohamed Fawzy
Published: February 2024

Solar energy has gained prominence as a primary renewable energy source for the generation of electricity in recent years. The maximization of power extraction from photovoltaic (PV) systems is a topic of significant interest due to the relatively low conversion efficiency of these systems. Therefore, a maximum power point tracking (MPPT) controller is essential in a PV system to achieve the desired output power. This paper implements three different MPPT controllers: sliding mode control (SMC), fuzzy logic controller (FLC), and artificial neural networks (ANNs). The performance of these controllers is evaluated on a PV system under varying irradiation and temperature conditions to analyze their ability to track the maximum power point (MPP). The results demonstrate that the SMC outperforms the FLC and ANN in terms of best performance with minimum oscillation under different operating conditions.
Amino Acid Composition of Cow's Milk of the North Caucasus Black-and-White Breed
Authors: Trukhachev V. I. , Oleinik S. A. , Ershov A. M. , Zlydnev N. Z. , Pokotilo A. A. , Zakotin V. E. , Chernobai E. N. , Khodusov A. A.
Published: February 2024

The study of the amino acid composition of dairy raw materials, as shown in numerous studies of domestic and foreign authors, is relevant for conducting breeding work on genetic improvement of dairy, optimizing the system of raising animals of various sex and age groups, including lactating cows to prolong the productive longevity period. The purpose of the research was to study the amino acid composition of the milk of cows of the black-and-white Holsteinized breed, considering genotypic, age-related aspects, as well as with an increase in cow milk protein content. Studies on the composition of amino acids in milk were carried out on cows of a black-and-white breed of a pedigree breeding unit of the Stavropol Territory, the Russian Federation. The obtained results showed that the amino acid content in the black-and-white cow milk in the conditions of the North Caucasus corresponds to the parameters characteristic of the black-and-white Holsteinized breed, while the ratio of essential and interchangeable amino acids, considering age and genetic factors, varies in the range of 0.945-0.951, which is typical for high-quality milk. It was also found that in the process of increasing the protein content of cows by 0.2 abs. percentage from a protein level of 3.10% to 3.30%, a more intensive increase in essential amino acids in relation to interchangeable amino acids is observed, while the ratio of essential to interchangeable amino acids statistically significantly (p<0.05) increased by 1.66%, which is of particular importance for planning measures for the genetic improvement of protein content herds of black-and-white cattle.
Cronkhite-Canada syndrome with esophagus involvement and six-year follow-up: A case report
Authors: Tang Yu-Chen
Published: February 2024

BACKGROUND

Cronkhite-Canada syndrome (CCS) is a rare, noninherited disease characterized by gastrointestinal polyposis with diarrhea and ectodermal abnormalities. CCS polyps are distributed through the whole digestive tract, and they are common in the stomach and colon but very uncommon in the esophagus.

CASE SUMMARY

Here, we present a case of a 63-year-old man with skin hyperpigmentation accompanied by diarrhea, alopecia, and loss of his fingernails. Laboratory data indicated anemia, hypoalbuminemia, hypocalcemia, hypokalemia, and positive fecal occult blood. Endoscopy showed numerous polyps scattered throughout the digestive tract, including the esophagus. He was treated with nutritional support and glucocorticoids with remission of his symptoms.

CONCLUSION

Comprehensive treatment led by hormonal therapy can result in partial or full remission of clinical symptoms. Treatment should be individualized for each patient according to their therapy response. Surveillance endoscopy is necessary for assessing mucosal disease activity and detecting malignant transformation.
Do moments of inattention during study cause the error-speed effect for targets in recognition-memory tasks?
Authors: Voormann Anne , Meyer-Grant Constantin G. , Rothe-Wulf Annelie , Klauer Karl Christoph
Published: February 2024

The error-speed effect – characterized by a decreased performance in a second recognition task for stimuli that elicited fast error responses in a first recognition task – has so far been predominantly interpreted as evidence for the existence of misleading memory information. However, this neglects a possible alternative explanation, namely that the effect may instead be caused by moments of inattention during study. Here, we introduce a manipulation that allowed us to distinguish between words from the study phase that participants most certainly paid attention to and those they did not. We hypothesized that if moments of inattention cause the error-speed effect, this effect should disappear when considering only targets that verifiably received attention during study. However, our results (N = 89) suggest that this is not the case: The error-speed effect still occurs for targets that participants attended to during study and thus indeed seems to be caused by misleading memory evidence rather than by moments of inattention during study.
Violencia Intrafamiliar en Hombres de 20 a 59 Años Derechohabientes de la UMF 57 de Irapuato Guanajuato Durante el 2022
Authors: Cortés Rodríguez Carol , Ugalde Ramírez Irlanda Alicia , Jiménez Zavala Miguel Ángel
Published: February 2024

Objetivo. Determinar la prevalencia de violencia intrafamiliar en hombres de 20 a 59 años derechohabientes de la UMF 57 de Irapuato Guanajuato durante el 2022. Material y métodos. Se realizó un estudio descriptivo, prospectivo de corte transversal, en los derechohabientes del sexo masculino de la UMF 57 durante el 2022, los cuales fueron seleccionados a través de un muestreo no probabilístico por conveniencia. Se aplicó el cuestionario de violencia sufrida y ejercida de pareja (CVSEP). Resultados. Se entrevistaron a 251 derechohabientes hombres que acudieron a atención médica a la UMF 57, el promedio de edad fue de 37 años. La percepción de violencia sufrida por los derechohabientes obtuvo resultados positivos con un porcentaje de 21.9% (55) el 78.1% (196) percibió que no existe violencia, predominando el tipo de violencia Psicológica con un porcentaje del 72.7%, y de acuerdo a las características sociodemográficas es más frecuente en casados, con un tiempo de relación menor a 5 años con escolaridad de preparatoria. Conclusiones. Si existe la violencia intrafamiliar en hombres derechohabientes de la UMF 57, pero en muchas ocasiones no la manifiestan por temor a ser ridiculizados y poner en duda su masculinidad.
Brickets in A Review of The Philosophy of Science
Authors: Fithry Dwi Annisa , Legawati Lisa , Aulia Sari Ermal Dini , Maarasyid Cici , Jusnita Jusnita , Salsabila Naia , Febrian Amanda
Published: February 2024

Review draft briquettes in context philosophy knowledge this knowledge explains How to approach knowledge and can help us understand the production process, use, and impact environment briquettes. in perspective philosophy knowledge, production briquettes involve the use method scientific, like chemistry and engineering machines, to change biomass to become material burn solid. It involved understanding deep about traits chemistry and physics material standards, as well as the conversion process of energy. Impact environment from the use of briquettes. Using briquettes can influence the ecosystem and impact on the environment. Approach philosophy knowledge helps We dig questions about ethics use briquettes and effort to reduce the negative impact. The Aspect of social economy- related to the production and use of briquettes, like impact on the community local, and how knowledge can help understand the implications of this. This study gives an understanding deep about how briquettes can see through the lens of philosophical knowledge. This thing gives contribution is important in integrating knowledge, ethics, and impact socio-economic in understanding We technology energy alternatives like briquettes.
Rancang Bangun Counter Conveyor untuk Penghitungan Otomatis Hasil Produksi UMKM Keripik Talas
Authors: Ardianto Aldo , Sunaryo Sunaryo , Fauzi Muhammad Ridha
Published: February 2024

Counter conveyor merupakan alat yang digunakan untuk menghitung suatu objek seperti hasil produksi keripik talas. Pada poses produksi keripik talas permasalahan yang sering terjadi adalah lupa ketika menghitung jumlah hasil produksi. Ketika hasil produksi dilakukan penghitungan biasanya sering terjadi kesalahan penghitungan sehingga menyababkan penghitungan jadi berulang kali.Hal ini menyebabkan hasil produksi lambat disalurkan ke konsumen. Dari permasalahan tersebut, maka dibuatlah solusi dengan membuat alat penghitung otomatis yang dilengkapi dengan conveyor dengan teknik counter menggunakan sensor ultrasonic HC-SR04 sebagai pendeteksi objek yang melewati sensor, NodeMCU ESP826 berfungsi sebagai otak dari proses utama system, dan LCD 16x2 sebagai media tampilan hasil perhitungan produksi keripik talas dan juga dilengkapi dengan sistem IOT (Internet Of Thing) yang mana untuk mentranfer data hitungan ke smartphone atau komputer melalui jaringan. Dengan diterapkannya rancang bangun counter conveyor ini, maka dapat disimpulkan bahwasanya dapat mempermudah perhitungan secara real dan realtime.
Improvement of Functional State of Patients after Spinal Cord Injury During Epidural Electrical Stimulation: Prospective Study
Authors: Shchurova Elena N. , Prudnikova Oxana G. , Kachesova Anastasiia A. , Saifutdinov Marat S. , Tertyshnaya Marina S.
Published: February 2024

the lack of convincing evidence of a therapeutic effect.
AIM. To evaluate the effect of complex rehabilitation using EPS and activation of the proprioceptive apparatus on the indicators of the functional state of patients with long-term consequences of spinal cord injury with partial spinal cord injury.
MATERIALS AND METHODS. A prospective study was conducted with the participation of 29 patients with long-term consequences of spinal cord injury with partial spinal cord injury. The catamnesis of the disease was 3.7 ± 0.5 years. Comprehensive rehabilitation included epidural electrical stimulation by implantable electrode and activation of the proprioceptive apparatus. The neurological (ASIA scale) and functional (CSIM III scale) status of the patient was analyzed. Motor function was evaluated using 10-meter Walk test; M-responses of limb muscles — using electromyography, temperature and pain sensitivity — using esthesiometry.
RESULTS. An increase in muscle strength and M-response of the muscles of the extremities, normalization of the motor deficit index, reduction of the walking test time, increase in movement speed and the patient’s independence index were revealed. There is an improvement in temperature and pain sensitivity at the level of damage and in the dermatomes located distally. The effect decreases in dermatomes far from the level of the electrode installation; but with increase in the number of courses the effect increases.
DISCUSSION. The results obtained indicate that this rehabilitation complex, including UES, has a positive effect on the functioning of both the motor and sensitive spheres.
CONCLUSION. Application of EES and activation of the proprioceptive apparatus improves the functional condition of sensorimotor sphere in the long-term consequences of spinal cord injury with partial spinal cord damage. Repeated rehabilitation courses have cumulative effect.
Features of Mental Disorders in Right- and Left-Hemisphere Localization of Stroke on the Background of Motor Rehabilitation: Comparative Study
Authors: Kuzyukova Anna A. , Belyaeva Irina A. , Pekhova Yana G. , Yurova Olga V. , Fesyun Anatoliy D.
Published: February 2024

INTRODUCTION. In post-stroke patients have a high incidence of cognitive and emotional pathology, it is very important to take into account the particular features of mental state in order to achieve significant results of rehabilitation. The data on brain asymmetry indicate a certain lateralization of some mental functions (speech, emotional and cognitive functions).
AIM. To study cognitive, emotional disorders and quality of life in patients with ischemic stroke depending on the localization of the lesion in the right or left cerebral hemisphere and their dynamics on the background of motor rehabilitation.
MATERIALS AND METHODS. 39 patients with localization of an ischemic focus in the middle cerebral artery territory (group 1 (n = 19) — right hemisphere, and group 2 (n = 20) — left hemisphere) in the recovery period after an ischemic stroke, underwent an inpatient course of motor rehabilitation. Conditions of the patients were assessed at the beginning and at the end of hospitalization using the 6-point muscular strength scale, the modified Ashfort scale, a TUG test, the FIM and Berg balance scales, MMSE, MoCA, the Schulte Table methods, he Beck Depression Inventory, the State-Trait Anxiety Inventory (Spielberger-Khanin) and the Quality of Life at stroke.
RESULTS. Attention disorders were found in patients of groups 1 and 2 in 84.6 and 75 %, respectively. Emotional disorders were diagnosed in almost half of post-stroke patients, anxiety disorders prevailed over depressive ones. In group 2 patients scoring ≤ 23 points on the MMSE were found 5 times more frequently. In group 1 depression was 4 times more frequent. However, the obtained intergroup differences were not statistically significant. At the end of the rehabilitation, both groups demonstrated a significant decrease in the level of trait anxiety, and in group 1 an increase in the attentional stability.
DISCUSSION. The observed prevalence of more severe cognitive impairments in the LMCA group and emotional impairments in the RMCA group are consistent with the data on brain asymmetry.
CONCLUSION. Motor rehabilitation has a positive effect on the emotional state of patients after a stroke, and insignificantly on their cognitive functions, which, along with a high incidence of cognitive impairments, necessitates consideration of the transition from motor to cognitive-motor rehabilitation in order to improve the effectiveness of the treatment.
Efficiency of Remote Monitoring of Rehabilitation of Patients after Myocardial Infarction
Authors: Elfimov Dmitriy A. , Elfimova Irina V. , Kosterin Mikhail D. , Golubeva Alyona A. , Andreeva Olga V.
Published: February 2024

INTRODUCTION. Rehabilitation of cardiac patients is based on a set of measures of a rehabilitation nature (medical, physical, social, psychological and pedagogical). The purpose of this type of activity is aimed at restoring health as much as possible in a particular case, as well as psychological status. Despite widespread urbanization, the share of rural residents still remains significant and amounts to 25.1 %. They face limited access to health care more often than urban populations. This is especially true for the population of remote areas.
AIM. Evaluation of the effectiveness of the use of remote technologies during rehabilitation measures in patients who have suffered an acute myocardial infarction.
MATERIALS AND METHODS. The study included 200 patients who had suffered acute myocardial infarction, receiving outpatient rehabilitation at the City Clinic No. 17, living in the city of Tyumen. The patients were divided into two equal groups of 100 people. The average duration of treatment in both groups was 21 days. The rehabilitation program included a therapeutic and physical training complex, which took place in a face-to-face group as part of joint classes, and in a remote group — at home using video instructions, previously sent by email.
RESULTS AND DISCUSSION. Rehabilitation with the use of remote technologies showed a result comparable to the full-time program. In both groups, there is a statistically significant improvement in the indicators of the Rankin, and rehabilitation routing scales. However, according to the Aronov scale, positive changes are present only in the remote group.
CONCLUSION. Based on the results of the study, a conclusion was made about the comparable effectiveness of cardiac rehabilitation in full-time and remote groups. This suggests that biomedical technologies can be used in the implementation of cardiac rehabilitation programs in areas remote from large settlements.
Effectiveness of Sulfide Balneopeloidtherapy in Patients with Hypertension in Comorbid Combinations: Randomized Prospective Study
Authors: Vladimirskiy Vladimir E. , Vladimirskiy Evgeny V. , Hassaballa Rahma F.M. , Karakulova Yulyia V. , Gulyaeva Natalya I.
Published: February 2024

INTRODUCTION. In the treatment of cardiovascular diseases, the use of hydrogen sulfide, which is a universal gas transmitter and performs many physiological functions in the body, is of interest.
AIM. To evaluate the effectiveness of sulfide balneopeloid therapy (SBPT), carried out at the Klyuchi resort (Perm region), in patients with arterial hypertension (AH), as well as their combinations with coronary heart disease (CHD), prediabetes and cerebrovascular disease (CVD) with chronic ischemia brain (CHM).
MATERIALS AND METHODS. A comparative randomized prospective study was conducted at the Klyuchi resort (Perm region), which studied the effectiveness of SBPT in patients with hypertension in various comorbid combinations. General inclusion criteria were the presence of hypertension and age from 40 to 70 years.
RESULTS. The results of a study of the effectiveness of different durations of SBPT in patients with hypertension showed that when a course of SBPT was carried out for 14 days, the hypotensive effect was less significant, while mid-term observation revealed that the hypotensive effect after a 21-day course of SBPT persisted for up to 6 months, and after 14-day course — 3 months. In patients with hypertension and prediabetes, complex therapy, including 14 days of SBPT, helps reduce the severity of clinical manifestations and improve quality of life; causes redistribution of fat deposits, improvement of blood pressure profile, aortic compliance, endothelial and neurogenic circuit of skin microcurrent regulation; reduces the serum concentration of vascular endothelial growth factor (VEGF), leptin, and also increases the serum concentration of transforming growth factor beta 1 (TGF-β1). When treating patients with hypertension and coronary artery disease using SBPT, an increase in the activity of the parasympathetic part of the nervous system, a lipid-correcting effect, improvement of endothelium-dependent vasodilation and exercise tolerance. The results of a study of patients with hypertension with CVD and MS showed that patients who received a course of SBRT had a significant improvement in cognitive functions.
DISCUSSION. The effects that develop during SBPT are associated with the polymodal effect of the H2S molecule on the main metabolic signaling pathways and regulatory mechanisms of the body’s hormonal-humoral systems, which leads to optimal regulation of micro- and macrohemodynamics, favorable changes in lipid metabolism, trophological status and trophic factors.
CONCLUSION. SBPT, carried out at the Klyuchi resort (Perm Region), is effective in patients with hypertension, including various comorbid combinations — hypertension and prediabetes, hypertension and ischemic heart disease, CCI.
CPR verde como instrumento de geração de riqueza para o semiárido brasileiro
Authors: Figueiredo Erik Alencar de
Published: February 2024

O decreto que instituiu a Cédula de Produto Rural (CPR) Verde, em outubro de 2021, marcou o início da consolidação do mercado de compensação voluntária de emissões de carbono, oferecendo segurança jurídica e possibilitando que produtores rurais sejam remunerados pela preservação ambiental durante o ciclo produtivo agrícola. Este processo envolve o produtor rural emitindo uma CPR Verde em favor de um comprador, com a promessa de entrega de produtos ambientais certificados. Embora inicialmente tenha direcionado a atenção para regiões verdes como a Mata Atlântica e a Amazônia, levanta-se a questão de como a CPR Verde pode gerar riqueza no Semiárido brasileiro. Para isso, será necessário promover uma mudança na matriz energética de algumas atividades, como cerâmica, celulose e papel, siderurgia, beneficiamento de mandioca, entre outros, substituindo a lenha por biomassa. Esta estratégia pode impulsionar o desenvolvimento regional e reduzir a dependência de recursos naturais. O estudo propõe a expansão dessa experiência de economia de carbono em setores industriais do Semiárido, visando gerar benefícios socioeconômicos e ambientais significativos. Essa reflexão destaca a necessidade de projetos setoriais, mensuração do mercado potencial e modificações na legislação da CPR Verde para incluir atividades com impacto ambiental, mas não diretamente relacionadas à produção rural. Essas ações são fundamentais para impulsionar o desenvolvimento sustentável e reduzir as desigualdades regionais no Brasil.
Indicador ambiental
Authors:   Brasil. Instituto de Pesquisa Econômica Aplicada (Ipea). Diretoria de Estudos e Políticas Regionais Urbanas e Ambientais (Dirur), Urbanas e Ambientais (Dirur)
Published: February 2024

O Instituto Nacional de Pesquisas Espaciais (Inpe) monitora rotineiramente os focos de calor em todo o Brasil, utilizando registros do satélite Aqua MODIS. Esses focos são indicadores importantes de mudanças no uso do solo, e em 2020 o Brasil registrou 222.798 focos, um aumento de 12,7% em relação ao ano anterior. Esse aumento segue uma tendência já observada em 2019, sendo o maior número desde 2012. Áreas como o oeste de Rondônia, o Matopiba e o Pantanal nos estados do Mato Grosso e Mato Grosso do Sul foram particularmente afetadas em 2020. Municípios como Poconé e Barão de Melgaço no Pantanal Mato-Grossense registraram as maiores densidades de focos de calor no país. O governo federal, através da Superintendência de Desenvolvimento da Amazônia (Sudam), está desenvolvendo o Projeto Amacro para promover o desenvolvimento sustentável nos estados do Amazonas, Acre e Rondônia, diante da intensa transformação no uso do solo, exigindo uma intervenção estatal para ordenar esse processo.
Instrumentos de gestão municipal: contribuições dos municípios para as políticas públicas ambientais e dos recursos hídricos no nordeste brasileiro
Authors: Sousa Janaildo Soares de , Caetano Francisco Aquiles de Oliveira , Frota Marisa Guilherme da , Silva Andréa Ferreira da , Sousa Érika Costa
Published: February 2024

A preservação ambiental e a gestão dos recursos hídricos são cruciais para o desenvolvimento sustentável e a continuidade da vida na Terra, refletido na Agenda 2030 da ONU. A gestão integrada desses recursos em todos os níveis governamentais é fundamental para alcançar metas como a disponibilidade sustentável de água e saneamento básico. Este artigo destaca a importância da gestão municipal dos recursos hídricos e ambientais no Nordeste brasileiro, visando analisar a implementação de instrumentos de gestão, identificar estados com diferentes níveis de gestão e avaliar a relação entre gestão hídrica e ambiental. A pesquisa justifica-se pela escassez de estudos nessa área, pela democratização das políticas públicas locais e pela relevância do município na prestação direta de serviços públicos. Considera-se que uma gestão eficaz dos recursos hídricos e ambientais a nível municipal contribui para a promoção do desenvolvimento sustentável e a redução das externalidades negativas ao meio ambiente, fortalecendo assim as políticas públicas em âmbito local, estadual e nacional.
Estratégia de vacinação em massa contra covid-19 nas fronteiras brasileiras
Authors: Nunes Maria
Published: February 2024

A vacinação contra a Covid-19 no Brasil teve início em janeiro de 2021, porém, enfrentou desafios decorrentes da escassez de doses, retardando o cronograma de imunização. O país, devido ao seu papel nas pesquisas de vacinas, possuía vantagens geopolíticas na aquisição dos imunizantes, destacando-se pela capilaridade da rede do Programa Nacional de Imunizações (PNI) e sua participação na fase clínica de várias vacinas. No âmbito regional, iniciativas como o Prosul buscaram impulsionar a cooperação entre os países sul-americanos para enfrentar a pandemia, incluindo aquisição conjunta de vacinas e fortalecimento de mecanismos colaborativos. No entanto, apesar das intenções de cooperação fronteiriça, a prática mostrou-se inconsistente, com fechamentos unilaterais de fronteiras e falta de coordenação entre municípios fronteiriços, evidenciando desafios significativos na mobilidade e na resposta coordenada à pandemia.
nálise de impacto regulatório de políticas urbanas e ambientais
Authors: Saccaro Junior Nilo Luiz , Seixas Luiz Felipe Monteiro
Published: February 2024

O texto aborda a dicotomia entre o planejamento urbanístico e ambiental no Brasil, destacando suas repercussões na produção normativa e políticas públicas, especialmente no que diz respeito à eficiência da gestão urbana, competitividade e atração de investimentos. Questionamentos sobre a possibilidade de novos arranjos regulatórios e de governança são levantados, buscando promover o desenvolvimento urbano sustentável com critérios de eficiência e desburocratização. São propostos objetivos de levantamento de literatura, diagnóstico de problemáticas, descrição de metodologias de avaliação e análise de impacto, além do desenvolvimento de produtos como textos para discussão e webnários. Os próximos passos incluem a análise da viabilidade de um índice municipal de regulação urbana e a criação de um modelo de análise de impacto regulatório para questões ambientais.
Análise do investimento a partir de microdados da pesquisa industrial anual
Authors: Cruz Bruno de Oliveira , Cavalcante João Pedro , Ferreira Glaucia Estefânia de Souza
Published: February 2024

O estudo da dinâmica de crescimento econômico destaca a importância do investimento e da acumulação de capital, tradicionalmente analisados em nível macroeconômico, mas que, a partir dos anos 1990, ganharam uma nova abordagem microeconômica. Esta nova perspectiva, baseada na avaliação do comportamento do investimento em nível de planta, visa entender seu impacto na economia como um todo. Cruz e Boucekkine (2017) revisam essa literatura, destacando a concentração do investimento em poucos anos, caracterizada por picos de investimento. No contexto regional, o avanço das contas regionais pelo IBGE proporcionou uma análise mais detalhada, embora a falta de dados sobre a FBCF seja um desafio. Esforços como os de Silva e Monteiro Neto (no prelo) e Morandi (2011) tentam estimar o investimento por meio de proxies, enquanto a pesquisa atual utiliza os microdados da PIA do IBGE para analisar o comportamento do investimento em nível de firma e planta, contribuindo para o entendimento do ajuste de capital no Brasil em um nível microeconômico. As duas linhas de pesquisa buscam aprofundar o entendimento do investimento e da sua relação com o crescimento econômico, fornecendo insights valiosos para os analistas regionais e para a contabilidade do crescimento.
Subsídios e proteção comercial agrícolas na União Europeia
Authors: Freitas Rogério Edivaldo
Published: February 2024

O texto discute a relação entre subsídios e proteção comercial nos mercados globais de produtos agropecuários, destacando a importância histórica das rodadas do Acordo Geral sobre Tarifas e Comércio (GATT) na regulação dessas práticas. Embora a Rodada Uruguai tenha representado um avanço na regulamentação de subsídios à produção e exportação de produtos agropecuários, as expectativas para a Rodada de Doha não se concretizaram, resultando em um enfraquecimento do multilateralismo e um aumento do foco em acordos bilaterais entre grandes atores como a União Europeia (UE), Estados Unidos e China. O texto tem como objetivo analisar a trajetória dos subsídios agropecuários da UE no período de 2000 a 2020 e avaliar a proteção comercial exercida por este bloco em relação às importações de alimentos, fornecendo insights relevantes para formuladores de políticas públicas e privadas, especialmente do ponto de vista brasileiro. O trabalho é estruturado em cinco seções, incluindo uma introdução, uma seção sobre a importância da UE no contexto global agropecuário, metodologia, resultados e considerações finais.
Indicadores fiscais dos estados da federação no período 2020-2021
Authors:   Brasil. Instituto de Pesquisa Econômica Aplicada (Ipea). Diretoria de Estudos e Políticas Regionais Urbanas e Ambientais (Dirur)
Published: February 2024

O texto analisa indicadores fiscais dos estados da federação no período de 2020 a 2021, destacando quatro principais indicadores: endividamento, serviço da dívida, parcela do resultado primário servindo à dívida e índice de vulnerabilidade fiscal (IVF). Observou-se uma redução significativa no indicador de endividamento em todas as regiões, com alguns estados apresentando posição credora no final de 2021. O serviço da dívida decresceu na maioria dos estados, exceto Tocantins, e houve variação nos resultados primários, com alguns estados mudando de superavitários para deficitários. O IVF mostrou aumentos expressivos em alguns estados, enquanto outros melhoraram sua situação fiscal. Esses dados refletem a dinâmica econômica e fiscal dos estados brasileiros ao longo do período analisado.
Indicador da cadeia produtiva agropecuária
Authors:   Brasil. Instituto de Pesquisa Econômica Aplicada (Ipea). Diretoria de Estudos e Políticas Regionais Urbanas e Ambientais (Dirur), Urbanas e Ambientais (Dirur)
Published: February 2024

O texto aborda diversos aspectos relacionados à economia brasileira, destacando indicadores como o Produto Interno Bruto (PIB), com suas taxas de crescimento anual e valores correntes, e o Valor Bruto da Produção Agropecuária (VBPA), além de temas como comércio internacional, política de crédito, insumos como fertilizantes e investimentos federais em transportes. São evidenciados impactos da pandemia da COVID-19, como a queda nas exportações do agronegócio, e aspectos como o aumento dos preços de importação de fertilizantes e a redução dos investimentos federais em transportes ao longo dos anos, refletindo um cenário de retração econômica.
Situação do acesso aos serviços de saneamento no Brasil nos municípios que apresentam aglomerados subnormais
Authors: Nadalin Vanessa Gapriotti
Published: February 2024

O texto aborda as desigualdades na prestação de serviços de saneamento no Brasil, com foco nos territórios informais, especialmente nos aglomerados subnormais (AGSNs). Apresenta as mudanças legais recentes e discute a Lei nº 14.026/2020, que visa promover a universalização dos serviços com participação da iniciativa privada. Explora as diferenças nos indicadores de inadequação no abastecimento de água e esgotamento sanitário entre áreas de AGSNs e não especiais, em 323 municípios brasileiros, utilizando dados da Pesquisa Nacional de Saneamento Básico e do Perfil dos Municípios Brasileiros de 2017. Além disso, analisa como essas diferenças se relacionam com a gestão dos serviços e seu planejamento, considerando variáveis como tipo de prestador do serviço, existência de Plano Municipal de Saneamento, entre outros. A pesquisa destaca os desafios enfrentados na ampliação do acesso aos serviços de saneamento nos AGSNs, ressaltando a importância de políticas específicas e o envolvimento da comunidade no processo de planejamento
Mosaico fundiário e o parcelamento irregular no Distrito Federal: o cenário de 2021
Authors: Martins Anamaria de Aragão Costa , Ivo Sávio de Lima , Leitão Francisco das Chagas
Published: February 2024

O artigo aborda as implicações das ocupações informais e não planejadas no Distrito Federal, destacando seu papel na expansão urbana em áreas rurais. Inicialmente, discute-se a problemática fundiária e a dificuldade de controle estatal sobre as terras, introduzindo conceitos como a expectativa de regularização permanente e seu ciclo vicioso. Em seguida, são analisados os dados da pesquisa, que revelam a tendência de ocupação além dos limites da urbanização consolidada e das áreas planejadas para expansão urbana. Por fim, o artigo propõe ferramentas para auxiliar o planejamento urbano, identificando pontos no território com potencial para formar novos núcleos urbanos e discutindo a natureza das terras onde esses agrupamentos surgem, com foco nos parcelamentos irregulares, especialmente os de classe média.
Licenciamento urbanístico integrado no Brasil: um futuro atrasado
Authors: Paranaíba Adriano de Carvalho , Ferro Felipe Pessoa
Published: February 2024

O artigo investiga as questões regulatórias relacionadas ao licenciamento urbanístico no Brasil e as tentativas recentes de melhoria. Destaca-se a baixa qualidade da estratégia nacional de regulação urbanística, evidenciada pelo relatório Doing Business de 2020, que classificou o Brasil em 170º lugar no indicador de obtenção de alvarás de construção. Apresenta-se a Resolução CGSIM no 64, de 11 de dezembro de 2020, que buscava estabelecer critérios para dispensa de atos públicos de liberação de obras de baixo risco, mas que foi revogada após uma semana de vigência. O texto analisa essa proposta à luz dos princípios de liberdade econômica e redução do fardo burocrático, visando oferecer insights sobre possíveis soluções para os desafios enfrentados no licenciamento urbanístico no Brasil.
Iniciativas de cooperação transfronteiriça em matéria de saúde
Authors: Nunes Maria , Galindo Ernesto Pereira , Gatti Flávio
Published: February 2024

Este ensaio examina as iniciativas de cooperação transfronteiriça em saúde e como a pandemia da covid-19 afetou esses mecanismos, especialmente no fornecimento de serviços para fronteiriços estrangeiros. Considerando as medidas de controle adotadas, como o fechamento das fronteiras, o estudo investiga os desafios enfrentados e as estratégias de cooperação entre os países fronteiriços. Utilizando dados de questionários aplicados em 48 localidades fronteiriças brasileiras entre agosto e dezembro de 2021, o estudo analisa as mudanças na dinâmica de cooperação e compartilhamento de serviços de saúde antes e durante a pandemia. O texto é dividido em três seções, abordando os desafios na cooperação para acesso e provisão de serviços de saúde, as iniciativas de cooperação existentes antes da pandemia e suas alterações durante a crise de saúde, e as considerações finais sobre o tema.