bluuebunny/crossref_metadata_2025 huggingface dataset:
MLPA-analysis of TP53 gene in patients with small-cell lung cancer
Authors: Гималова Г.Ф. , Абдуллин З.С. , Хуснутдинова Э.К.
Published: November 2020

Мелкоклеточный рак легкого (МРЛ) составляет около 15-20% всех случаев РЛ и относится к наиболее злокачественно текущим опухолям. В более чем 90 % случаев МРЛ выявляются мутации гена TP53. Целью нашего исследования являлся анализ структурных изменений хромосомной области 17p13 у больных МРЛ из Республики Башкортостан. Материалом исследования служили 70 образцов тканей легких больных МРЛ. Методом исследования являлся MLPA-анализ. Делеции и/или дупликации в кодирующих областях гена TP53 выявлены в 40% образцов, в т.ч. дупликации первого (23% образцов) и делеции 4-6-го и 11-го экзонов гена TP53 (17% образцов). Кроме того, в четырех образцах выявлена мутация c.1100delC гена CHEK2.

Small cell lung cancer (SCLC) accounts for about 15-20% of all lung cancer cases and is one of the most malignant tumors. In more than 90% of cases of SCLC, mutations of the TP53 gene are detected. The aim of our study was to analyze the structural changes in the 17p13 chromosomal region in patients with SCLC from the Republic of Bashkortostan. We used 70 lung tissue samples from patients with SCLC. The study was conducted using MLPA. Deletions and/or duplications in the coding regions of the TP53 gene were detected in 40% of the samples, including duplications of the first exon (23% of the samples) and deletions of the 4-6th and 11th exons of the TP53 gene (17% of the samples). Besides, the CHEK2 c.1100delC mutation was detected in four samples.
Polymorphic variants of DNA repair enzyme genes in the pathogenesis of lung cancer in women
Authors: Титов Р.А. , Минина В.И. , Баканова М.Л. , Савченко Я.А.
Published: November 2020

Обследовано 540 жительниц Кемеровской области: 270 человек, первично обратившиеся для диагностики и лечения в Кемеровский областной онкологический диспансер и 268 человек - здоровые женщины доноры Кемеровского областного центра крови (группа сравнения). Цель: изучение роли полиморфизма генов репарации ДНК в формировании рака легкого у женщин. Типирование полиморфных вариантов генов APEX1 (rs1130409), XRCC1 (rs25489), hOGG1 (rs1052133), XPD (rs13181), XPG (rs17655), XPC (rs2228001), ADPRT (rs1136410), АТМ (rs18015), NBS1 (rs1805794) осуществляли методом аллель-специфической ПЦР. Стaтистическую обрaботку результатов проводили с использованием программ: SNPstats (http://bioinfo.iconcologia.net/SNPstats), «Statistica 10.0» (StatSoft, Inc., USA). Выявлены ассоциации полиморфных вариантов генов APEX1 (rs1130409), hOGG1 (rs1052133), XRCC1 (rs25489), АТМ (rs18015), XPC (rs2228001) c формированием рака легкого у женщин.

In the presented «case-control» study 540 residents of the Kemerovo Region subject to age, sex and smoking status were included. We formed two groups: 1) «Case» - 270 newly diagnosed lung cancer patients undergoing a medical treatment in the Kemerovo Regional Oncology Center; 2) «Control» - 268 healthy donors of the Kemerovo Regional Center of Blood Transfusion. Statistical analysis were performed using SNPstats (http://bioinfo.iconcologia.net/SNPstats), «Statistica 10.0» (StatSoft, Inc., USA). A significant association obtained between the APEX1 (rs1130409), hOGG1 (rs1052133), XRCC1 (rs25489), АТМ (rs18015), XPC (rs2228001)) and lung cancer.
The role of GC-rich sequences in cell-free DNA in the activation of DNA sensors using the cancer line MCF7 as an example
Authors: Малиновская Е.М. , Кожина Е.А. , Ершова Е.С. , Конькова М.С. , Вейко В.П. , Бобровский П.А. , Лазарев В.Н. , Каменева Л.В. , Вейко Н.Н. , Костюк С.В.
Published: November 2020

Основные вопросы исследования: (1) Взаимодействие рецепторов TLR9 и AIM2 в клеточной линии MCF7 в ответ на действие ГЦ-богатых фрагментов в составе внеклеточной ДНК (ГЦ-вкДНК); (2) Изучение роли рецепторов TLR9 и AIM2 в опосредовании биологического действия ГЦ-вкДНК на клетки MCF7.

The major research questions: (1) Interaction of TLR9 and AIM2 receptors in MCF7 in response to the action of GC-rich fragments in cell-free DNA (GC-cfDNA); (2) Studying the role of TLR9 and AIM2 receptors in mediating the biological effect of GC-cfDNA on MCF7 cells.
Reflexiones sobre el Código Civil italiano y peruano
Authors: Benatti Francesca
Published: November 2020

En esta ocasión, ADVOCATUS tuvo la oportunidad de entrevistar a la abogada italiana Francesca Benatti, profesora asociada de Derecho Privado Comparado de la Universidad de Padua. A través de las siguientes líneas se ofrece un breve análisis sobre la vigencia del Código Civil peruano y el Código Civil italiano, abordando elementos del Derecho Civil, incluyendo la responsabilidad civil y el derecho de las personas, así como el derecho comparado.
Herbal Oil and its Anti-arthritic Activity
Authors: Dinesh Babu J  , Vinaya J  , Sravan Kumar P  , Akhila CR
Published: November 2020

Inflammation and arthritis are interrelated conditions that are caused by each other. This disorder majorly occurs in elderly patients. It is a major problem in the world that affects the joints and causes inflammation in the joints causing pain and tenderness in the joints. This is mainly triggered by the inflammation caused by the malfunctioning of the immune system of the own body. This disease leads to severe damage to the cartilage of the joints in the body. This will lead to the ankylosing of the joints and resulting in the pain of the joints. There are few other diseases like inflammation of the pleural cavities, scleritis and other lesions that are usually seen in the cutaneous, subcutaneous tissue. Overall, it is a problem in the immune system of the body. The researchers now had concentrated on the utilization of the herbs and medicinal plants to treat arthritis effectively. They are found to be safe and effective compared to the synthetic immune suppressant drugs. They are also the cheapest sources of drugs. So the herbs had been investigated for the production of the newer molecules that treat arthritis effectively and relatively safer with that of the existing drugs. The plant extract of the stem bark of the plant Berberis orthobotrys was collected and extracted using ethanol. This was used to prepare oil formulation, and this was investigated for the anti-arthritic activity. The oil formulation showed a better activity compared to the extract and compared to the standard.
Akut Lenfoblastik Lösemili Çocuklarda İdame Tedavisinin Nadir Bir Komplikasyonu: Folik Asit Eksikliği
Authors: BÜYÜKAVCI Mustafa , ERKUN Olena , PALA Ayşegül , ORHAN Mehmet Fatih
Published: November 2020

Vitamin B12 (cobalamin) and folic acid play a crucial role in DNA synthesis, cell division and proliferation. Their deficiency may cause serious disorders of hematopoietic, gastrointestinal and neurologic system. A 14-year-old girl, undergoing maintenance chemotherapy (methotrexate, 6-mercaptopurine) for acute lymphoblastic leukemia (ALL), presented with the complaints of pallor and nose bleeding. At admission, white blood cells (WBC) was 2230/mm3, hemoglobin 6.2 gr/dL, mean corpuscular volume (MCV) 122 fL and thrombocytes 26700/mm3. Peripheral blood smear revealed hypersegmented neutrophils, macrocytosis, anisocytosis, rare normoblasts and 4-5 platelet per field. Bone marrow aspiration and biopsy did not confirm the pre-diagnoses of relapsed ALL, hemophagocytic lymphohistiocytosis (HLH) and myelodysplastic syndrome (MDS). Vitamin B12 and folic acid were prescribed after obtaining the results of vitamin B12 (587 pg/mL), folic acid (1.3 ng/mL) and homocystein (21 µmol/L). Folic acid deficiency must be kept in mind in childrenwith ALL receiving maintenance therapy. Serum cobalamin and folic acid levels must be checked in case of unexplained pancytopenia.
Nanotechnology and Nanobiomaterials: Redefining Ways of Managing Oral Cancer
Authors: JUNEJA Akanksha , SULTAN Amina
Published: November 2020

Nano-biotechnology can be considered as application of various nanotechnologies in the biological field. With the advent of nano-particles, a revolution has come in the scientific community. The convergence of nanotechnology and medicine recently led to an interdisciplinary field, nanomedicine, which brings together engineers, physicists, biologists, chemists, mathematicians, and physicians striving to improve detection, imaging, and drug-delivery devices. The approaches to nanomedicine range from the medical use of nanomaterials, to nanoelectronics biosensors, and even possible future applications of molecular nanotechnology. Cancer is a leading cause of mortality in the world. Cancers of the head and neck—including the salivary glands, thyroid, and the mucosal lining of the oral cavity, pharynx, nasopharynx, and larynx—account for the high percentage of malignancies of the world. At present the treatment modalities available are very limited. A multidisciplinary approach is needed, including the cooperation of biophysics experts, molecular biologists and medical practitioners, to find ways of using nano-biotechnologies for cancer management. Hence future research needs to focus on designing new strategies where nano-biomaterials and medicine can come together to find a cure.
A Preliminary Research on HLA-Association of Lumbar Spinal Stenosis
Authors: EFENDİOĞLU Mustafa , AKAR Ezgi , KOÇMAN Emine , BAŞARAN Recep , IŞITMANGİL Gülbu
Published: November 2020

Objective: We aim to identify the relationship lumbar spinal stenosis (LSS) and genetic HLA system.Materials and Methods: The present study investigates 15 cases out of 41 (7 male, 8 female; average age: 60.27) who were studied for HLA class I ABC genes, as well as totally 41 cases (19 male; 22 female; average age: 60.46) who were studied for HLA class II DR.DQB1 genes among the cases with LSS. DNA extraction, the DNA was amplified with primers specific to HLA-A, B, C, DQ and DR, and studied using the SSP-PCR method. Allele identification was made using the official HLA Nomenclature Committee software.Results: HLA A2 allele in LSS group (%36.7) is statistically significantly higher than control group (%17.2) (p:0.039; p<0.05). The frequency of the B44 allele was statistically significantly higher in the LSS group (20%) than in the control group (5.1%) (p:0.010; p<0.05). Likewise, the frequency of the C6 allele was statistically significantly higher in the LSS group (26.7%) than in the control group (8.6%) (p:0.013; p<0.05). Conclusion: This preliminary study has suggested that LSS is associated with HLA class I genes. HLA A2, HLA B44, and HLA C6 alleles have been determined as predisposing factors for LSS.
融资融券对真实盈余管理的影响研究
Authors: 曹 静 , 窦 论文
Published: November 2020

为了探究融资融券对真实盈余管理治理效应的外部机制，将市场监管引入模型，探究市场监管、市场化进程和产权性质在融资融券对真实盈余管理的政策效果中所发挥的作用。首先探究融资融券制度的实施是否对真实盈余管理存在治理效应。为了探究融资融券政策实施效果以及市场和公司特质在其中所发挥的作用，将市场作用细化为市场化进程与市场监管力度两方面，并引入产权性质，以A股上市公司2008-2018年的面板数据为样本，通过多期DID模型、分层回归和分组回归进行实证研究。研究结果表明，成为融资融券标的公司后，真实盈余管理水平相对于其他公司显著降低；市场监管在融资融券对真实盈余管理管理的作用中起倒U型的调节作用；市场化程度高的地区，融资融券的抑制作用明显；在非国有企业中融资融券的抑制作用明显。上述结果表明，融资融券可以抑制真实盈余管理，但该作用的发挥有赖于外部的市场和企业的特质，市场监管发挥着倒U型的调节作用，市场化进程有助于融资融券发挥作用，该作用在非国有企业中更显著。研究结果丰富了融资融券政策效果的经验数据，部分完善了融资融券对真实盈余管理影响路径的研究，对中国融资融券的发展和完善提出了一些建议。研究结果表明，成为融资融券标的公司后，真实盈余管理水平相对于其他公司显著降低；市场监管在融资融券对真实盈余管理管理的作用中起倒U型的调节作用；市场化程度高的地区，融资融券的抑制作用明显；在非国有企业中融资融券的抑制作用明显。上述结果表明，融资融券可以抑制真实盈余管理，但该作用的发挥有赖于外部的市场和企业的特质，市场监管发挥着倒U型的调节作用，市场化进程有助于融资融券发挥作用，该作用在非国有企业中更显著。研究结果丰富了融资融券政策效果的经验数据，部分完善了融资融券对真实盈余管理影响路径的研究，对我国融资融券的发展和完善提出了一些建议。
高质量发展下的事业单位人力资源培训开发
Authors: 庄 盈莹
Published: November 2020

近年来，中国积极推动经济转型升级和产业变革，更加重视经济增长质量，重视技术创新、绿色节约，对高质量发展提出了越来越高的要求。高素质人力资本作为创新驱动发展的根本，对高质量发展起着至关重要的作用。而影响知识与生产创新的重要因素便是人力资源开发的程度，科学的人力资源培训开发是挖掘人力资本潜能的一个重要和直接手段。论文分析了加强人力资源培训开发的意义和要点，围绕高质量发展下的事业单位人力资源培训开发展开分析探讨。
基于OBE的高职智能会计人才培养模式探究
Authors: 李 树叶
Published: November 2020

随着当前大数据技术以及互联网技术的快速发展，在会计行业当中，基层会计岗位的工作人员将会面临严峻挑战，会计工作人员需要紧随当前发展趋势进行职业转型发展。高职院校作为会计人才培养的重点单位，应当紧随当前时代发展以及技术变革趋势，大力培养会计基层岗位人员，基于OBE教育理念及模式，培养适应会计智能化发展方向的管理型、复合型会计工作人员。
煤炭行业人才队伍建设的路径选择
Authors: 张 瑜
Published: November 2020

煤炭企业是中国的重要企业，在中国经济建设和能源建设中有着重要地位。人才队伍建设工作，决定了企业明天的兴衰。煤炭企业要实现长远发展，需要不断完善行业人才队伍的建设。面对新市场、新课题，不断地调整我们的人才策略，为企业持续健康发展提供强大的人才保障。因此论文主要从煤矿行业人才队伍建设的现状、煤炭行业人才队伍建设的重要性和人才队伍建设的路径进行分析，探讨如何优化煤炭行业人才队伍的建设。
技能等级认定试点企业监管服务措施研究
Authors: 庄 星熠
Published: November 2020

国务院高度重视职业资格制度改革，将职业资格改革作为“放管服”改革重要内容。为深入推进改革，进一步简政放权，加快政府职能转变，形成科学化、社会化、多元化的技能人才评价机制，根据国务院召开常务会议的研究决定，人社部将按照“先立后破”“一进一退”原则，决定分步取消技能人员水平评价类职业资格，设立企业试点推行社会化职业技能等级认定，各地市鉴定中心将职能转变为监管服务。论文以对企业技能等级认定的后续监管问题为基础，对如何进行企业技能等级认定的监管服务进行深入分析。
“一带一路”倡议驱动下中国巴州地区旅游经济发展研究
Authors: 徐 蔼积
Published: November 2020

为了更好地推动中国巴州地区旅游经济的发展，论文采用SWOT分析方法，在分析巴州地区旅游经济发展现状的基础上，提出了“一带一路”倡议驱动下巴州地区发展旅游经济的措施，如注重旅游目的地形象的策划和宣传；设计有特色的旅游线路；加强“旅游+”战略，促进产业的融合发展；创新旅游投资体制；促进旅游经济的可持续发展等措施，来促进巴州地区的旅游经济的高质量发展，从而提高巴州旅游经济的核心竞争力和品牌知名度。
多措并举纾解小微企业融资困境
Authors: 李 同堃
Published: November 2020

小微企业是中国经济发展和社会稳定的重要基石，在中国出台一系列纾困惠企金融政策下，小微企业金融服务的便利性和可获得性得到逐步改善。但因融资成本高、融资渠道少、缺乏有效的抵押担保等因素，小微企业仍面临不同程度的融资难题。论文立足于小微企业的融资现状，从发展普惠金融的角度，力求多主体、多维度合力纾解其融资难题，助力小微企业可持续发展。
互联网经济时代青少年金融科技教育研究
Authors: 蔡 小路
Published: November 2020

开展金融科技教育是落实中国全民金融素养的重要手段，也是青少年的健康成长必不可少的环节之一。当前，青少年金融科技教育面临学习兴趣动力不足，金融教学质量不高，师资不足，研究薄弱等挑战。纵观发达国家的金融教育，他们已形成一套成熟的教育系统。论文结合青少年金融科技教育的现状分析，采用SWOT分析法从内外部环境分析，提出多形式、多角度提升青少年金融科技水平，加强金融科技的体验感和打造一支专业的金融科技科普队伍的建议。
中国宁夏红寺堡区生态移民文化素质及就业趋向调查
Authors: 郭 嘉禹 , 孙 艺宁 , 屈 昕然 , 张 起源 , 郭 佳澍 , 王 梓名
Published: November 2020

生态移民是因为生态环境恶化或为了改善和保护生态环境所发生的迁移活动以及由此活动而产生的人口迁移。生活质量的提高是生态移民区社会稳定的基本前提，而居民的文化素质影响就业状况，进而影响生活质量。因此，生态移民区居民的文化素质能否提高，就业状况是否改善，生活质量能否提升，决定生态移民的成败。论文以中国宁夏红寺堡区的5个村落和1个城镇社区为调查区域，通过深度访谈法深入探究当地的文化素质成因、就业趋向的影响因素，通过独立性检验探究文化素质与就业趋向之间的关系，并结合“互联网+”时代背景，从文化素质的角度，提出了基于普雷马克原理和班杜拉观察学习理论的几点建议，以期促进生态移民区的和谐稳定。
中国湖南南方杨家将史考
Authors: 杨 凯焱
Published: November 2020

中国历史长河中，出现了许许多多的爱国名将，如关羽、张飞、岳飞、戚继光、霍去病等都是爱国尽忠的民族英雄。杨家将人物故事被全国人民所熟知，研究杨家将历史文化与人物故事的专家学者比比皆是。杨家将忠勇爱国的英雄事迹，千百年来一直为人民所歌颂，所敬仰。中国湖南城步是全国闻名的杨姓县，有全国唯一的“杨氏官厅”、唯一的“杨家将文化艺术之乡”、唯一的“杨家将村”，杨家将历史文化是中华民族文化的文化瑰宝之一。
广西民歌传承与学校音乐教育个案研究
Authors: 黄 重宁
Published: November 2020

广西民歌是中国民间艺术文化当中的重要组成部分，拥有重要的艺术文化价值，但是在飞速发展的时代当中，广西民歌的传承和发展遇到了一些问题。当代中学音乐教育有必要让祖国未来的人才们了解这些珍贵的民间艺术，为其传承发展做出贡献。论文先分析了广西民歌传承的必要性和意义，再从中学音乐教育出发，分析广西民歌的传承目的，最后结合实际案例分析学校音乐教育中传承广西民歌的策略和措施。
石家庄红色文化与旅游产业深度融合问题研究
Authors: 韩 琳 , 赵 然 , 陈 芳
Published: November 2020

红色旅游是以中国共产党带领人民在革命和建设中创造的丰功伟业和铸就的功勋业绩而形成的纪念地与标志物为载体，以凝聚其中、彪炳史册的革命精神为内涵而组织的具有特定主题的旅游观光活动。红色旅游应该是自然景观和人文景观的高度融合，应该是在传承以爱国主义教育为核心的民族精神，以改革创新为核心的时代精神的基础上的旅游。中国河北省石家庄拥有平山县西柏坡、正定县塔元庄等得天独厚的红色文化资源，促进红色文化与旅游产业深度融合，促进石家庄红色旅游产业大发展大繁荣，是现阶段我们必须做好的工作。它不仅具有深刻的现实意义，更具有深远的历史价值
“以人为本”理念下中国高校教育管理创新发展探讨
Authors: 曾 同军
Published: November 2020

为了改进与完善中国高校教育管理工作，使中国高校教育管理适应社会的变革，从而全面实现人才强国，“以人为本”理念下中国高校教育管理的创新发展势必成为教育变革的方向与趋势。在此背景下，论文结合中国高校教育管理现状，深入分析了目前高等教育教学管理的现状与存在的问题，阐释了“以人为本”理念的内涵与高校教育管理模式的契合点，给出了“以人为本”理念下中国高校教育管理的策略以及创新发展的方式、方法与方向。本次研究内容为中国教育事业的创新发展提供了思路，具有一定的参考意义。
统编教材中语文要素教学的全学段实践
Authors: 鹿 沙沙
Published: November 2020

新教材是社会的发展和新课程改革的产物，它在选择课文上作出深度的思考。选文兼顾经典、可读性，选择了大量的思想调高、言行形式美，值得诵读的涵咏作品，同时考虑了文体的多样性，典范性和篇幅，适用于学生所能理解的深浅。既考虑了如何提高语文素养，又贯穿了“立德树人”的整体要求，还充分激发学生对自主学习的兴趣，给教师留下发挥空间。抓住教材在多方面的平衡点是非常不容易的，很多选文都是广泛征集意见并经过反复的讨论和斟酌后选出来的，教材选编尽可能地考虑了社会的共识。同时，教师也要更加注意，语文要素这一重要概念在语文教学中的重要作用，它对学生知识做了全面概括，让教师也能更加准确地将知识教授给学生。
“TBL-CBL-PBL”融合教学模式在数据库项目课中的应用
Authors: 陈 伟 , 郝 慧君 , 匡 芳君 , 高 巍巍
Published: November 2020

数据库课程是具有很强理论性和实践性的一门课程。“TBL-CBL-PBL”融合教学法结合三种教学方法的特点和优势，能激发学生学习兴趣和积极性，进行小组教学、小组讨论和案例分析，将学生置于案例情境中，有效解决核心问题。将融合教学模式应用于数据库项目课中，通过对比发现，能有效提高学生学习的主动性和积极性，学生学习效果提升较大，具有一定的推广价值。
基于商用公有云的实训环境建设研究
Authors: 傅 东亮
Published: November 2020

随着中国信息产业不断发展，职业教育中信息技术相关专业得到长足发展。计算机应用、计算机网络技术、软件技术、电子商务技术、信息安全与管理等已成为各个职业院校的网红专业。近期由于物联网、大数据、工业互联网的大发展，高职院校也相继出现了云计算技术与应用、嵌入式技术与应用、人工智能技术与应用等新兴专业。这些专业相比过去一些IT专业，更偏向于底层和后端。如何设置课程及搭建好实训环境是这些专业人士必须面临的问题。传统的实训室一次性投入及维护成本都较高，资源使用效率却较低、课堂实训效果不佳等问题比较突出。论文从广州松田职业学院云计算技术与应用专业实训建设经验中提炼，讲述基于商用公有云搭建实训环境的利与弊。
成人英语学习动机激发和培养的教学策略研究
Authors: 徐 文荟
Published: November 2020

成人学习者在英语学习过程中容易出现学习效果差，预期目标难以实现；学习缺乏毅力，半途而废的情况。究其原因，他们在学习过程中学习动机不断减退甚至消失有直接关系。论文通过研究影响成人英语学习者学习动机的主客观因素入手，提出一系列激发和培养成人英语学习者学习动机的策略以促进其英语学习活动持久、有效地进行。
Parkinson hastalığı ve diz sinoviyal kondromatozisin eş zamanlı birlikte bulunması
Authors: GÜVENER Orhan , ARINCI Nurgül , SARIKAYA Pınar
Published: November 2020

Sinovyal kondromatozis nadir görülen, etyolojisi kesin olarak bilinmeyen, iyi huylu bir artropatidir. Çoğunlukla diz, kalça, dirsek gibi büyük eklemlerde görülür. Bir metaplazi olduğu düşünülmektedir. Parkinson hastalığı, çoğunlukla insan yaşamının sonraki yıllarında ortaya çıkan ilerleyici multisistemik nörodejeneratif bir hastalıktır. Hastalık belirtileri daha belirgin hale geldiğinde, hasta el fonksiyonu ve yürüme ile ilgili zorluklarla karşılaşır ve düşmeye eğilimli hale gelir. Bu vaka sunumunda propriosepsiyon üzerinde potansiyel olumsuz etkisi olan Parkinson hastalığı ve diz sinovyal kondromatozisi birlikteliğini bildiriyoruz. Bu iki durumun olumsuz sinerjistik etkisine dikkat çekmek ve klinisyenlere nörolojik hastalıklarda eşlik eden eklem patolojilerini hatırlatmak istiyoruz.
Study of the parameters of the law of the force vibration excited by a centrifugal vibration exciter
Authors: Vasiliev Aleksandr Mikhailovich , Bredikhin Sergey Alekseevich , Andreev Vladimir Konstantinovich , Rudik Phelix  Yakovlevich
Published: November 2020

The article is devoted to the study of the parameters of the law of the force oscillations excited by a centrifugal vibration exciter of vibration machines.
Influence of agricultural facilities on the reliability indicator of gas distribution networks at their connection
Authors: Klochko Aleksey Konstantinovich , Zhila Viktor  Andreevich
Published: November 2020

The article presents a methodology and algorithm for calculating the reliability indicator of gas distribution networks.  The issues of choosing a scheme for connecting agricultural facilities to external gas distribution networks when supplying natural gas are studied. The indicators of reliability and technical and economic indicators of various connection options have been determined. Recommendations for choosing the required connection scheme are presented.
Opportunities for the development of Russian crop production in the context of global challenges
Authors: Golubev Alexey Valerianovich
Published: November 2020

It is shown that in the context of global challenges, the economy is being reformatted in favor of vital industries, including the agri-food sector. The apparently prosperous state of Russian agriculture and, above all, crop production, which demonstrates long-term growth of production even against the background of slowing down the dynamics of the domestic economy, is by no means unconditional. The development of the industry takes place in conditions of limited reproduction, largely due to the exhaustion of natural, labor, material, technical and financial resources. Such a paradox is fraught with the collapse of crops and problems in ensuring national food security. However, Russian agriculture, which has learned to survive in a crisis situation, with an effective agricultural policy, is capable of more intensive development in the face of global cataclysms. These prospects are connected with the possibility of a sharp increase in the production of natural products in vast territories that have preserved relict shades of agriculture; with the introduction of once abandoned agricultural land into circulation. The conditions that need to be created for the implementation of global competitive advantages of crop production are shown. The semantic analysis of leading publications is carried out, which allows identifying trends in promising world research in agricultural Sciences.
The dynamics of development of cotton bollworm (Helicoverpa armigera H?bner, 1805) and turnipmoth (Agrotis segetumSchif, 1775) (Lepidoptera; Noctuidae) in the sugar beet agrocenosis
Authors: Seliqe Gazı Galib
Published: November 2020

There is comprehensive information about the dynamics of the development of cotton bollworm (Helicoverpa armigera) and turnip moth (Agrotis segetum) belonging to order Lepidoptera in the sugar beet agrocenosis. The seasonal and diurnal flying-dynamics of both species, harmful period of the caterpillars in the agrocenosis, and some biological characteristics have been investigated during the studies. Obtained results can have practical importance for the control of these pests.
Response of wheat cells to ferrihydrite nanoparticles under model system in vitro
Authors: Stupko Valentina Yurievna , Zobova Natalya Vasilevna , Gurevich Yuri Leonidovich
Published: November 2020

High biological activity of nanoparticles (NPs) makes them promising for using in fertilizers composition. Design of such products is impossible without detection of active substance influence mechanisms on growth and development of plant as well as without detection of critical points, when influence of the investigated agent is at its maximum. Biogenic ferrihydrites (FH) are promising regulators of plant cell antioxidant system activity, also under edaphic stresses. Callus cultures are well known as convenient model system for screening of tissue and cell response to different environmental exposure. Investigation results of FH NP`s, which were produced by authors, influence on growth and development of callus culture of soft spring wheat mature wheat embryos of are presented in present article. The absence of competitive in relation to 2,4-D influence of involved levels of FH NPs (1 and 10 mg/l) on dedifferentiation process of embryo tissues was indicated. The presence of investigated agent induced the decrease of culture growth rate. However, postponed positive effect manifested in reduction of ageing rate after passing to fresh medium, the bigger, the higher had been FH NP`s level at the previous cultivation stage. The present effect may be of critical importance under field conditions under the influence of unfavorable edaphic and climatic factors, which adds further credence the potential of presented NPs applicability in agriculture.
Screening of pepper (Capsicum l.) seedlings tolerance to low temperature
Authors: Rajametov Sherzod Nigmatullaevich , Yang Eun Young , Cho Myeong Cheol , Chae Soo Young , Jeong Hyo Bong
Published: November 2020

This study was conducted on screening for 21 pepper genotypes tolerant to low temperature and their duration for survival in 3-4 (38 days after sowing), and 4-6 (47 days after sowing) true leaf seedling growth stages (LS). It was detected that response of seedlings on low temperature were different and ranged among the genotypes depends on growth stages. Seedlings in early 3-4 LS growth stage were more susceptible than 4-6 LS seedlings, where the first symptoms of leaf cold damages (LCD) were revealed within 7 days after transplanting (DAT) and 12 DAT in pepper seedlings, respectively. There were identified that the susceptible genotypes in 3-4 LS can be tolerant in 4-6 LS, or show opposite pattern, where tolerant one in next the growth stage, plant becomes susceptible. Low temperature negative impact on chlorophyll content (CHL) in leaves, however depends on seedling growth stage and genotype might be ranged. The lowest content of CHL were observed in early growth 3-4 LS seedlings than 4-6 LS. And, it was revealed that cold susceptible pepper genotypes in which CHL reduced significantly during cold treatment, showed good ability to recovery of CHL after treatment of seedlings in NT condition, whereas cold tolerant genotypes with high CHL content during low treatment, can reduce significantly of CHL after transfer of seedlings to NT condition for recovery. According to screening were selected relatively cold tolerant pepper genotypes LT8 and LT9 in early 3-4 LS, and LT8, LT13, LT18, LT20 and LT21 in 4-6 LS, where LCD were below 45 and 10%, respectively.
Scientific basis of feeding and keeping poultry
Authors: Okolelova Tamara , YEngashyev Syergyey
Published: November 2020

The book covers the basic principles of nutrient rationing for poultry. The data on the needs of all types of poultry, taking into account age, in nutrients, minerals and biologically active substances are given. The characteristic of the main feed means and rational norms of their inclusion in the compound feed for poultry are given. Modern data on the role of vitamins, macro- and microelements, enzyme preparations, probiotics, prebiotics, phytobiotics, organic acids, antioxidants, fat emulsifiers and other sources of biologically active substances in poultry nutrition are presented. Attention is paid to the main technological parameters of poultry keeping. The nutritional factors that reduce immunity, as well as the causes of the main diseases associated with the quality of feed, with violations in the rationing of nutrient, mineral and biologically active substances, the technology of feeding and keeping poultry, are described, methods of their prevention are given. Criteria for the adequacy of nutrition and maintenance of a bird to its genetic potential are stated. The book is intended for specialists and managers of poultry farms, enterprises of the feed industry, researchers, graduate students and students.
International protection of human rights: universal mechanisms
Authors: Samovich Yuliya , Sharifullin Ramil
Published: November 2020

The tutorial examines the universal mechanism for the international protection of individual rights, in particular the United Nations system and treaty bodies. Special attention is paid to the analysis of the effectiveness of the international control mechanism and proposals for its improvement. The content will allow students to both independently fill in the missed material and get acquainted with additional. The manual is recommended for students in the direction 40.04.01 "Jurisprudence" (magistracy), graduate students, specialty students.
A STUDY ON WORK-LIFE BALANCE OF NURSING STAFF WORKING IN PRIVATE HOSPITALS IN PALAYAMKOTTAI
Authors: Suguna G. , Franco C.Eugine
Published: November 2020

At present every successful employee has to pass through the dilemma of work life balance in personal and professional life. For the sake of leading a successful life, people do not hesitate to give extra time for achieving the objectives of life. In the process of getting extra mileage in their professional life they have to make a lot of compromise and sometimes mental piece also gets distorted. We have 24 hours at our disposal to deal with and it is up to us how to schedule and plan the same. It is rightly pointed out by experts, if our life span is 60 years (assumed to be) and if we sleep for 8 hours per day, than 20 years of our life span we used for sleeping only. So planning of our own time is important. At the end of the day priority matters a lot. In addition, relationships suffer and the person begins to experience loneliness and depression. The psychotherapist believes that mid-career professionals are most prone to having work-life imbalances. In the present paper it is an attempt by authors to present a study on work life balance dilemmas faced by nurses working in private hospitals. This study is based on primary sources of data and to some extent secondary sources. Various authentic journals, books and literature on the subject, newspapers, magazines, reports and studies were referred for the conceptual frame work of the study. The analysis is carried out on the basis of socio economic profile and general perception towards the personal and professional life.
İdrarda Orotik Asit’in Temassız İletkenlik Dedektörü Kullanılarak Kapiler Elektroforez Yöntemi İle Hızlı Tayini
Authors: CANSEVER Mehmet Şerif , ÖZTEKİN Nevin , ADIMCILAR Veselina , ZÜBARİOĞLU Tanyel , KIYKIM Ertuğrul , AKTUĞLU Ayşe
Published: November 2020

İdrarda orotik asidin aşırı atılımı üre döngüsü bozukluğu ve pirimidin sentez bozukluğu gibi doğumsal metabolik hastalıklarda görülür. Bu nedenle orotik asidin hızlı bir şekilde tayini hayati öneme sahiptir. Bu çalışmada idrar örneklerinde orotik asidin kantitatif düzeylerinin belirlenmesi için yeni, basit, ucuz ve hızlı bir kapiler elektroforetik analiz yöntemi geliştirildi. Orotik asidin temassız iletkenlik dedektörü (C4D) kullanılarak kapiler elektroforez yöntemi ile ayrımı için pH’ı 6,5 olan 20 mM 4-Morfolinetansülfonik asit (MES), 10 mM Histidin ve 0,1 mM setil trimetilamonyum bromür (CTAB) içeren bir ça-lışma tamponu ile geliştirildi. Orotik asidin ayrılması yaklaşık 3,5 dakika gibi kısa bir sürede tamamlandı. Göç zamanlarının ve düzeltilmiş pik alanlarının tekrarlanabilirliği sırasıyla %RSD olarak 1,25 ve 4,31 olarak bulundu. En düşük dedeksiyon limiti (LOD) 0,733 mg / L ve en düşük tayin limiti de (LOQ) 2,443 mg / L olarak bulundu. Metodun idrarda orotik asit düzeylerinin tayin edilmesinde kolaylıkla ve hassasiyetle kullanılabileceği gösterildi.
Ultrasonik Ortamda Biyokömür Kullanarak Sulu Çözeltiden 5-Florourasilin Giderilmesi: Yanıt Yüzey Modellemesi ve Optimizasyonu
Authors: AKAY Sema
Published: November 2020

Kemoterapide en çok reçete edilen aktif maddelerden biri olan ve atık su arıtma tesisi sahasında yaygın olarak bulunan 5-Florourasilin (5-FLU) adsorpsiyonu, kağıt çamuru ile buğday kabuklarından üretilen biyokömürle ultrasonik ortamda gerçekleştirilmiştir. Adsorbent olarak kullanılan biyokömür, SEM, EDX, BET, FT-IR ve XRF analizleri ile karakterize edilmiştir. Yanıt yüzey modellemesi ve Box-Behnken tasarımı kullanılarak optimum koşullar ile 5-FLU konsantrasyonu, adsorpsiyon zamanı ve adsorbent miktarı parametrelerinin etkileri araştırılmıştır. Adsorbent miktarı en etkili parametre olarak belirtilirken, optimum adsorpsiyon koşulları: konsantrasyon = 5,48 mg/L, adsorbent miktarı = 1,61 g, zaman = 39,61 dakika olarak tahmin edilmiş ve bu şartlarda % 95,99 oranında adsorpsiyon gerçekleşeceği belirlenmiştir. Langmuir izoterm modeli deneysel veriler için daha iyi bir uyum (R2 = 0,999) göstermiş ve maksimum adsorpsiyon kapasitesi (qmax), Langmuir izotermiyle gösterildiği gibi 5,75 mg/g olarak bulunmuştur. Kinetik olarak adsorpsiyon işlemi, kemisorpsiyonun hız sınırlayıcı adım olduğunu gösteren pseudo birinci derece model olarak belirlenmiştir.
Novel Heterocyclic Azo Compounds: Synthesis, Characterization and DFT Calculations
Authors: IRMUMINOVA Shahodat , SEZGİN Barış , TİLKİ Tahir
Published: November 2020

Today, it is of great importance to synthesize new azo compounds as well as to conduct research in different areas of use. More than one usage area is increasing day by day in high-tech products (laser printing materials, printer toners, liquid crystals, etc.) as well as in many sectors such as paper, food, cosmetics, textile and leather. In this study, considering these advantages, the compounds of 3-amino-1H-pyrazol-5-ol, 1H-1,2,4-triazol-3-amine, 3-amino-1H-phenyl-5-ol were used as starting materials. As a result of azo coupling of diazonium salts with resorcinol and 3,5-dihydroxy benzoic acid, new azo compounds were synthesized, their structures were characterized by spectroscopic methods such as FT-IR and 1H-NMR, and different solvent effects on visible absorption spectra were investigated. Molecular geometry and vibration frequency calculations of synthesized compounds were made with Density Functional Theory (DFT) using 6-311G (d,p) basis set and B3LYP level. Additional, electronic properties and HOMO-LUMO orbital calculations were carried out with time dependent DFT (TD-DFT) approach. As a result of this study, it has been observed that azo compounds containing heterocyclic amine groups have batchromic effects and bright colors. It is anticipated that this study will make important contributions to the literature and the dyestuff industry and will form a basis for potential applications.
Helyum Atomunun İkili Uyarılma-İyonlaşma Rezonans Profillerinin 10o-80o Açı Aralığındaki Değişimlerinin İncelenmesi
Authors: KAYAR Nurçin , ÖZER Zehra Nur
Published: November 2020

Bu çalışmada, elektron spektrometresi kullanılarak, Helyum (He) atomunun rezonans düzeylerinin açısal değişimleri ölçülmüştür. 200 eV enerjili elektron demeti, yüksek vakum ortamında He atomları ile çarpıştırılarak koparılan ve saçılan elektronlar dedekte edilmiştir. Elektron spektrometresi deney düzeneği; vakum sistemi, elektron tabancası, hedef gaz He, saçılan ve koparılan elektronları dedekte eden iki elektron enerji analizörü, elektron dedektörleri, sinyal işleme ünitesi ve Faraday Elektron Toplayıcıdan (FET) oluşmaktadır. Bu çalışmada, soygaz element serisinde olan Helyum atomunun kendiliğinden iyonlaşma enerji seviyeleri 10o-80o açı aralığında incelenmiştir. Enerji değerleri 32,5-35 eV olarak alınmıştır. Küçük açılarda rezonans profillerinin simetri durumlarının daha baskın olduğu görülürken, büyük açılara doğru kayıldıkça hem simetrik hem asimetrik yapıda oldukları görülmüştür.
Formulation and Evaluation of Antioxidant Peel-Off Face Mask Containing Red Dragon Fruit Rind Extract (Hylocereus polyrhizus Haw.)
Authors: Jani Trasna Arman , Hakim Aliefman , Juliantoni Yohanes
Published: November 2020

Peel-Off face mask is one of the cosmetics that is used to treat skin from free radicals. Peel-off face mask can minimize the effects of free radicals because it contains antioxidant. One of the antioxidant sources is red dragon fruitÃ¢â¬â¢s rind (Hylocereuspolyrhizus Haw.). The aim of this study is to obtain Peel-Off face mask of red dragon fruitÃ¢â¬â¢s rind extract that contains anthocyanin. Red dragon fruitÃ¢â¬â¢s rind was macerated by ethanol 96%, ethyl acetate and n-hexane added citric acid (4:1) solvents. TLC test used Chloroform: ethyl acetate: n-butanol (5:4:1) eluent and sprayed by AlCl3. Antioxidant activity of extract was tested using DPPH (1,1-Diphenyl-2-Picryhidrazyl) method. Peel-Off face mask was made using PVA, HPMC, methyl paraben, propylparaben, propylenglycol, extract, ethanol 96% and aquadest. The rendemen of ethanol 96% extract was 9,476%, ethyl acetate extract was 0,783% and n-hexane extract was 0,631%. The results of TLC test showed yellow spots on the ethyl acetate and ethanol 96% extracts which indicated that extract contained flavonoids (anthocyanin). The results of antioxidant activity test showed that IC50 value of ethanol 96% extract was 189,7422 (AAI=0,2087), ethyl acetate extract was 196,9398 (AAI=0,2011), and n-hexane extract was 385,3664 (AAI=0,1027). The result of the product evaluations showed that all the formulas complied the product requirements such as the organoleptic, homogenity, pH, dispersive power and drying time. Peel-off face mask already meet the product requirements but further research is needed to test the product stability and activity.
Penggunaan Bahan Ajar IPA berbasis Pendekatan SAVI (Somatic, Auditory, Visual, Intellectual) untuk Meningkatkan Hasil Belajar Peserta Didik
Authors: Sari Fitran
Published: November 2020

Tujuan penelitian ini meningkatan hasil belajar peserta didik menggunakan pendekatan berbasis SAVI (somatic, Auditory, Visual, Intellectual) pada kelas VII-1 semester genap tahun pelajaran 2016/2017 materi organisasi tingkat kehidupan. Jenis penelitian ini adalah Penelitian Tindakan Kelas model Kemmis dan Tanggart terdiri 3 siklus. Adapun tahapan setiap siklus terdiri dari perencanaan (planning), Tindakan (Action), Observasi (observation) dan refleksi (reflection). Subyek penelitian adalah peserta didik kelas VII-1 berjumlah 26 orang. Adapun hasil penelitian Tindakan Kelas menunjukkan peningkatan setiap siklus. Siklus I memperoleh  rata-rata skor  peserta didik 25, aktivitas pendidik 77 % ketuntasan secara klasikal 0%, siklus II rata-rata skor  51, aktivitas pendidik 86 %, ketuntasan secara klasikal 41,6%, siklus III rata-rata skor  peserta didik 72, aktivitas pendidik 91%  dan kekuntasan secara klasikal 71%. Dengan demikian dapat simpulkan bahwa penggunaan bahan ajar IPA berbasis pendekatan SAVI dapat meningkatkan hasil belajar peserta didik.
Low-Field Magnetic Resonance Imaging Findings in Children with Seizures in Ibadan, Nigeria
Authors: Akinmoladun JA , Ogbole GI , Famosaya ID , Joel RU
Published: November 2020

Background: Seizure is the most common neurological disorder in children and an important cause of paediatric hospital admission with the highest prevalence in the under-five age group. Magnetic Resonance Imaging (MRI) is the neuro-imaging technique of choice in the initial evaluation of children with epilepsy. High-field MRI is the ideal imaging modality for evaluating seizures but this is not readily available in developing countries.
Objective: To analyse the spectrum of MRI findings in children presenting with seizures using a low-field (0.36T) MRI.

Methods: Children aged ≤18years with seizures, with cranial MRI at the University College Hospital (UCH), Nigeria between January 2013 and June 2015 were retrospectively reviewed.

Results: There were a total of 134 patients with 53% as adolescents and most of them (85; 63.4%) had abnormal cranial MRI findings. More male children had abnormal findings (52; 61.2%) and most abnormal findings (42; 49.4%) were reported among adolescents. The most frequent abnormality was hydrocephalus (23.5%) from various causes followed by cerebral tumours (14.1%) and ischaemic cerebral infarcts (11.8%). In the adolescents, intracranial tumours (21.4%) were the most frequent abnormal findings, while hydrocephalus was commoner in children aged less than 10 years, accounting for 33.3% and 36.0% among the 1-5 years and 6-11 years age groups respectively.

Conclusion: Low-field MRI, which is more readily available, can provide substantial preliminary findings to aid the management of children with epilepsies. Improved access to high-field MRI through cost reduction and early MR imaging evaluation in the course of illness are desirable.
Prevalence and Risk Factors of Hypovitaminosis D in Nigerian Children with Sickle Cell Anaemia
Authors: Adekunle MO , Njokanma OF , Solarin AU , Dada AO , Animasahun BA , Ubuane P
Published: November 2020

Background: Vitamin D deficiency (VDD) has been linked to some acute and chronic bone disorders that commonly complicate sickle cell anaemia (SCA) in children. Some of these bone diseases include chronic pain, reduced bone density and fractures. Despite Nigeria having the highest number of children with SCA in the world, there is a paucity of data on vitamin D status and the associated risk factors in affected children.

Objective: To determine the prevalence and risk factors for hypovitaminosis D in children with sickle cell anaemia in steady-state.

Methods: A total of 174 children with sickle cell anaemia aged one to eighteen years were recruited at the Sickle Cell Foundation Centre, Lagos. Baseline sociodemographic, clinical, anthropometric and laboratory parameters (serum 25-hydroxyvitamin D, corrected serum calcium and alkaline phosphatase) were recorded.

Results: The prevalence of vitamin D insufficiency and deficiency were 12.6 % and 72.5% respectively. Children below six years of age were less likely to have hypovitaminosis D compared to the older age groups (p = 0.017). The mean serum corrected calcium was lowest in subjects with vitamin D deficiency (p >0.001). Age and hypocalcaemia are independent predictors of hypovitaminosis D.

Conclusion: There is a high prevalence of vitamin D deficiency among children with sickle cell anaemia. Children aged below six years and with those with hypocalcaemia had higher odds of hypovitaminosis D.
Communication Between Healthcare Providers and their Clients: How Accurately do Mothers Remember the Indications for the Caesarean Section that they had?
Authors: Enabudoso EJ , Ajakaiye LE , Okoror CEM
Published: November 2020

Background: The indication for Caesarean delivery is one of the most important information required in the antenatal care and delivery mode for women with previous Caesarean section(s).

Objective: To assess the level of agreement/disparity between mothers’ report and the actual medical indication for Caesarean delivery and to explore factors associated with it.

Methods: This cross-sectional study was carried out among 248 women who were delivered by Caesarean section. A comparison was done between the patient's report of the indication for the Caesarean section and the physician's record and the level of similarity was recorded.

Results: More than half (126; 50.7%) of the respondents reported indications that were classified as complete similarity [Group A] while Groups B to E had 54 (21.8%), 21 (8.5%), 26 (10.5%) and 21 (8.5%) responses respectively. Of the group with “non-similar” responses, foetal indication accounted for 36.1% of them. Parity was the only predictor of “similarity”. Compared to para 0, para 1-4 were more likely to report “similarity” in the indications for the Caesarean section (AOR = 3.370; 95% CI = 1.277-8.888).

Conclusion: While the past obstetric history is an important aspect of the evaluation of the pregnant woman, it is important to attempt greater verification of facts at history taking for the indications for previous Caesarean section, especially when it has to do with foetal health as the indication, and in the nulliparae.
FEATURES OF PUBLIC ADMINISTRATION IN SHAPING STRATEGY OF VENTURE INVESTMENT OF BUSINESS ENTERPRISES
Authors: Parubchak Ivan , Hrynyshyn Halyna
Published: November 2020

The purpose of this study is to define the content of the category “venture investment”, and to establish the relationship between the concepts of “venture investment” and “venture capital”, to analyze the state of venture investment in Ukraine and determine its role in innovative development of the economy, to systematize international experience consider the possibility of its adaptation in Ukraine. Object of research: venture capital in the system of financing innovation processes in the modern economy. The methodological basis of the study is a set of general scientific and special methods of cognition. Methods of analysis and synthesis, generalization and scientific abstraction were used in the formation of the conceptual and categorical apparatus. The analysis of approaches to understanding the essence of venture investment, its components was carried out using dialectical and systemic-structural methods. The application of the historical and logical method, induction and deduction made it possible to study the genesis of the theory of economics and enterprise management, the factors of the strategy of development of venture investment of business entities. Within the framework of the study of the current state of venture investment, calculation and analytical methods of observation, measurement, analysis and comparison are used. Conclusions. Based on the above study, we can assume that venture capital is a combination of financial, human and intellectual resources, which with a high level of risk is invested in the development and implementation of high-tech products of companies that are in their infancy and initial development and are not listed on the stock market and in case of success brings its owner a profit that is much higher than the industry average. Despite the riskiness of investments, venture investments have a number of attractive prospects and advantages. As world experience shows, venture-backed companies are better prepared to innovate, grow faster and create more jobs in the future.
Research on Public Participation in Public Procurement: In the Context of Digital Economy
Authors: Huang Jiangyu , Li Jing
Published: November 2020

Public participation in public procurement is an important guarantee for its sustainable and healthy operation. In the era of digital economy and big data, public participation in information disclosure, service quality, and service pricing in public procurement plays an important role. Public private partnerships are an innovative form of public procurement. This study sorts out the issues of public participation in PPP projects, and puts forward several suggestions based on data thinking. In terms of public procurement project information disclosure, big data technology is used to improve the timeliness and breadth of information disclosure, and enhance the professionalism of information disclosure. Performance-oriented public procurement focuses on service quality, and guarantees service security through information platforms and professional third parties. The stakeholders use big data to supervise social organizations, so that they actively represent the public to file lawsuits in public procurement and relieve the public’s damaged rights and interests. The protection of the public’s right to know, suggest and supervise is inseparable from the training of professional talents by universities. Colleges and universities attach great importance to the cultivation of big data-oriented public procurement professionals, which includes improving teachers’ teaching ability, building a new knowledge system that combines big data and public procurement, and setting professional courses for students at different learning stages through connotative development.
Dependência e autonomia nas políticas externa e tecnológica do Brasil, 1951-79
Authors: Toledo Demétrio Gaspari Cirne de
Published: November 2020

Este artigo examina um conjunto de políticas externas do Brasil do ponto de vista de suas conexões com as políticas tecnológicas no segundo governo Vargas (1951-4) e nos governos Kubitschek (1956-61), Jânio Quadros e João Goulart (1961-4), Costa e Silva (1967-9), Médici (1969-74) e Geisel (1974-9). A partir de uma discussão sobre os vínculos entre dependência e autonomia tecnológica nas relações centro-periferia do capitalismo mundial, investiga as convergências entre política externa e política tecnológica. A hipótese que move o trabalho é que ao longo do período 1951-79 os formuladores das políticas externa e tecnológica se tornaram crescentemente conscientes da relação entre autonomia tecnológica e desenvolvimento, e buscaram criar sinergias entre uma política e outra. A análise desses dois conjuntos de políticas permite compreender as prioridades e o real alcance e constrangimentos que uma impôs à outra.
Crítica ao conceito de subimperialismo: a dimensão sul-americana da política externa brasileira e as limitações das análises dependentistas
Authors: Nogara Tiago Soares
Published: November 2020

O artigo a visa analisar o conceito de subimperialismo, inerente à Teoria Marxista da Dependência (TMD),verificando sua formulação, aplicação e validade para caracterizar a dimensão sul-americana da política externa brasileira ao longo dos governos Lula (2003-2010). A hipótese do trabalho é de que o conceito apresenta limitações para definir a inserção internacional brasileira, reproduzindo visões que contraditoriamente afirma desafiar. Na primeira seção, será apresentado um resgate teórico da formulação do conceito de subimperialismo. Em seguida, serão expostas as principais críticas à política externa brasileira embasadas no conceito de subimperialismo. Por fim, essas críticas serão contrapostas às proposições da política externa brasileira com relação às temáticas da integração regional e das relações bilaterais com países sul-americanos.
Resenha: The Political Economy of the Investment Treaty Regime
Authors: Amorim Lucas Silva
Published: November 2020

A resenha aborda o livro The Political Economy of the Investment Treaty Regime, escrito em coautoria por Jonathan Bonnitcha , Lauge N. Skovgaard Poulsen e Michael Waibel. Os autores exploram as principais características do Regime dos Tratados de Investimento, arcabouço jurídico formado por tratados de investimento, regras procedimentais e decisões de tribunais arbitrais. Um renovado movimento de crítica e reformas reforça a relevância do estudo do tema.