bluuebunny/crossref_metadata_2025 huggingface dataset:
Inactivation and Heme Degradation of Horseradish Peroxidase Induced by Discharge Plasma
Authors: Ke Zhigang , Huang Qing
Published: June 2013

The effects of non‐thermal plasma at the argon gas–solution interface on horseradish peroxidase (HRP), a classical heme‐containing protein, were assessed quantitatively. Evidence from spectroscopic approaches showed that enzymatic activity together with the contents of heme and iron in HRP decreased dramatically and concomitantly upon plasma treatment. The plasma induced both long‐ and short‐lived reactive species which inactivated HRP in the solution. In particular, hydrogen peroxide broke the heme prosthetic group into fluorescent products, mainly dipyrrols and their derivatives, while other factors such as hydroxyl radicals and UV radiation generated during plasma discharge accelerated this heme protein degradation process.
Treatment of multiple failures in process hazard analysis
Authors: Baybutt Paul
Published: June 2013

Process hazard analysis (PHA) is used to identify hazard scenarios. These hazard scenarios may be initiated by single or multiple failures. Other scenario events, such as the responses of safeguards, are also subject to multiple failure, and enabling events may combine with initiating events or other scenario events to produce a type of multiple failure. If multiple failures are not addressed in PHA, important scenarios may be missed, and the risks of scenarios may be underestimated. This article describes the meaning and types of multiple failures that are possible, discusses their importance, and provides an approach for addressing them in PHA. © 2013 American Institute of Chemical Engineers Process Saf Prog 32: 361–364, 2013
Process safety management: 21 years plus or minus: What i wish i'd known then and what we can't afford to forget now!
Authors: Brackey Alan C.
Published: June 2013

This article provides practical thoughts and insights on the essence of Process Safety Management (PSM), distilled from the author's 34 years in the industry, the past 19 of which have been spent solely in PSM practice. It focuses on several key elements, which make up the “heart and soul” of PSM and comments on the importance of and a few of the challenges presented by each of these elements. It offers some thoughts on key focus areas as PSM continues to move forward and briefly touches on a few of the frustrations that can be encountered in PSM practice. A key takeaway relates to the importance of never losing a sense of one's own vulnerability with regard to future PSM events. © 2013 American Institute of Chemical Engineers Process Saf Prog 32: 260–263, 2013