bluuebunny/crossref_metadata_2025 huggingface dataset:
Counterfeit News Detection Using Machine Learning
Authors: P.R SHANI
Published: August 2024

World is advancing rapidly. Doubtlessly we have different advantages of this Digital world anyway it has its impediments moreover. There are different issues in this cutting-edge world. One of them is fake data. Someone can easily spread fake news. Fake news is spread to hurt the remaining of an individual or an affiliation. Fake news is counterfeit information that is formed and conveyed by dishonest person. Clients are uninformed that the information that they got is deluding information. Using Machine learning that can orchestrate whether the news is substantial or deceiving through setting up the model. There are different web based stages where the individual can spread the fake news. This consolidates Twitter, face book, Instagram, Whatsapp, etc. ML is the piece of man-made awareness that helpers in making the structures that can learn and perform different exercises. Simulated learning computations will recognize the fake news thus at whatever point they have arranged. A collection of machine learning computations are available that consolidate the controlled computer based intelligence estimations like Decision Tree, Random forest , Stochastic gradient Descent, K Nearest Neighbor. As a rule simulated intelligence estimations are used for assumption reason or to perceive something hidden away.
Lived Experiences of Kindergarten Teachers in Developing and Maintaining a Positive Relationship with Parents and Families
Authors: Luna Tabudlong Leah La , D. Gallardo Remigilda
Published: August 2024

The role of kindergarten teachers in fostering a positive relationship with parents is crucial for a child's educational journey. This study aimed to explore the specific challenges, coping mechanisms, and insights that kindergarten teachers encounter and employ. Utilizing a qualitative phenomenological approach, the study involved kindergarten teachers from Sta. Maria, Davao Occidental. Data were collected through in-depth interviews and focus group discussions and were subsequently analyzed through thematic analysis. Two main themes emerged for challenges: Structural and logistical challenges and socio cultural and emotional complexities. For coping mechanisms, the themes were open and honest communication, providing emotional and academic support for students, and individualized problem-solving. Insights gained included the importance of strong teacher-parent ties, good communication to clear misunderstandings, and the role of parent involvement in a child's academics. The study's findings have broad implications for various stakeholders, including educational policymakers and school administrators. The identified challenges point to the need for interventions such as cultural sensitivity training and strategies to increase parental involvement. The coping mechanisms and insights can be integrated into teacher training programs and can inform the development of best practices for family engagement in early childhood education.
The Influence of Collaborative Professional Development to the Self-Efficacy of Teachers
Authors: G. Guindulan Gieryl
Published: August 2024

This study determined the relationship between collaborative professional development and teacher self-efficacy. Utilizing quantitative methodology, specifically descriptive correlation, the study measured the degree to which collaborative professional development affect teacher self-efficacy. A survey questionnaire was distributed to teachers who selected using census as a sampling technique. In analyzing the data, mean, Pearson-r and regression analysis were used. Based on the analysis of the data, the research reveals significant correlations, suggesting a mutually beneficial relationship between these two critical elements in education. The study confirms that teachers who actively engage in collaborative professional development practices exhibit markedly higher levels of self-efficacy. This has vital implications for the educational sector, signaling that fostering a collaborative environment can serve as a viable strategy to empower teachers, thereby positively impacting student outcomes. The findings of this study underscore the urgent need for establishing an educational ecosystem that champions collaborative efforts among teachers as a means of enhancing their professional abilities and, by extension, improving the quality of education. Therefore, it serves as a vital resource for policymakers, educators, and researchers in their quest to create a more supportive and effective educational environment for all involved parties.
A Critical Study on Artificial Intelligence and its Impact on Sports Business
Authors: Sureshbabu Sharadh , Lavaraju B.
Published: August 2024

Artificial Intelligence (AI) has become a born- again force throughout different industries including the sports business arena. Artificial Intelligence is now being used in sports increasingly due to its capability to provide various advantages in this field such as enhancing athletes performances & health, smooth the way for training & diet programs, assessing games & building approaches, refreeing. scouting & hiring players, forecasting the matches, selling tickets & even the sports journalism. The Global AI in the Sports Industry is anticipated to increase from the numbers 518.8 Million in 2022 to 4.3 Billion Dollars by 2028 at a CAGR of 42.3% over the predicted tenure. By 2030, the worldwide influence of AI is in prospect to attain $19.9 Billion. As a matter of fact, use of AI makes the sports events & tournaments more professional & the introduction of AI will take physical education to the next level. With the aid of these AI, big data & other facts & figures apparatus schools can initiate a unique & scientific physical education environment. My objectives is to evaluate the existing regulatory framework governing AI & its impacts on sports business, To compare between the countries with regard to AI & its impact on sports business development, To create awareness among the people with regard to AI & its impact on sports business, To understand the disadvantages of AI on sports industry & its negative impacts & To propose different ideas & recommendations can be given on the enhancement of AI & its impacts on sports business. The author has collected 202 samples. The researcher has undertaken the empirical research method. The scope of having advancements in the field of sports & its related business in the upcoming years is possible only via the utilisation of AI tools to compete in bigger stage is purely in the hands of the government of our country & people as in the case of AI there should be a balance between the cons/pros & the development in an arranged manner to get rewards in this particular arena in the near future.
Hypnosedation in Uterovaginal Brachytherapy: A Promising Alternative to Anesthesia
Authors: Taouchikht M. , Abdou S. , Fares H. , Yaacoubi A. , Lahdiri I. , Nouni K. , Lachgar A. , Kacemi H. El , Kebdani T. , Hassouni K.
Published: August 2024

Cervical cancer poses a significant health challenge in Morocco, and uterovaginal brachytherapy is essential for treating advanced cases. This study evaluates the use of hypnosedation as an alternative to traditional anesthesia methods during brachytherapy. Conducted over two months at the National Oncology Institute in Rabat, Morocco, the study included five patients previously treated with external radiotherapy and chemotherapy. Hypnosedation was used in the 3rd and 4th brachytherapy sessions, replacing spinal analgesia. Patients reported a reduction in pain and expressed high satisfaction with hypnosedation compared to traditional methods. This approach offers a promising alternative to conventional anesthesia, providing effective pain management and improved patient comfort.
Evaluation of Jati (Jasminum grandiflorum L.) mouthwash and Jati Kwatha (decoction) in Mukhapaka (aphthous stomatitis): An open-label, randomized, placebo-controlled clinical study
Authors: Balakrishnan Geethu , Mohanan Arun , Ramesh N. V.
Published: August 2024

Background:

Leaf extract of Jati (Jasminum grandiflorum L.) has been proven to possess dermal wound healing and anti-ulcer activities. Mukhapaka (aphthous stomatitis) is the most common lesion of the oral cavity. For its management, Jati mouthwash was formulated by the Arka (distillation), and its efficacy was compared with the traditional form of Jati Kwatha (decoction). Due consideration was given to patient compliance, convenience of usage, increased shelf-life, no preservative, easy storage, and dispensing.

Aims:

The aim of this study was to evaluate the efficacy of Jati mouthwash and Jati Kwatha Kavala (gargle) in the management of Mukhapaka. ]

Materials and methods:

Forty-five patients having the classical symptoms of Mukhapaka were randomized into three groups as Jati mouthwash (group 1), Jati Kwatha Kavala (group II), and placebo (group III), all preparations were administered twice daily for seven days. The assessment was done by scoring method evaluating the oral ulcer activity, ulcer-related pain and functional disability, and Visual Analog Scale (VAS) at the baseline each day. Statistical evaluation was done within groups using paired t-test and between the groups using ANOVA post hoc multiple comparisons – Tukeys test.

Results:

Significant reductions was observed in VAS score for pain and other symptoms in the Jati mouthwash group at the end of seven days. Furthermore, the mouthwash group noted an accelerated mean healing period. Gas chromatography–mass spectrometry spectrum of the drug in its modified form as distillate revealed the presence of thymol and carvacrol, which are proven effective against oral pathogens but were absent in the Kwatha.

Conclusion:

Although the disease is self-limiting and the management is supportive, the Jati mouthwash was found to be better than its classical form of Kwatha or decoction.
Dip eyes in water technique (Akshi Nimanjjana): Efficacy of a simple technique in the management of meibomian gland dysfunction
Authors: Maheshwari Puneet , Gopalani Ajay , Gopalani Meena , Rahim MSG Ram
Published: August 2024

Background:

Dip eyes in water (DEW) is an ancient technique to improve eye hygiene. Conventionally, the eyes are cleaned by splashing water on them. However, splashing is not very effective as the eyes get closed reflexly when the water is splashed onto the eyes. On the other hand, in the DEW technique, it is conveniently possible to keep eyes fully open when dipped inside the water in the eye cup. Meibomian gland dysfunction (MGD) is a chronic, frustrating disease for which there is no gold standard, and eye hygiene is presumed to play an important role.

Aim:

The present study was tested in a cohort of MGD patients using the DEW technique.

Materials and methods:

DEW was prescribed to seven patients who were symptomatic for a period ranging from 6 months to 2 years. The main four symptoms were irritation in the eyes, persistent watering of the eyes, burning sensation, and foreign-body sensation. The scale of assessment of these four symptoms was severe (+++), moderate (++), mild (+), and no symptoms (−). The outcome assessment criteria were complete relief in these four symptoms and were assessed after 1 year of starting treatment. The DEW technique was performed 3–4 times per day. It was added to the ongoing conservative treatment. Once complete relief was obtained, other conservative management measures were stopped, and only the DEW treatment continued. It was advised that the DEW treatment be continued as a part of the regular eye hygiene daily routine.

Results:

Five out of seven patients reported complete relief in outcome criteria (four symptoms), one had partial relief, and there was no relief in one of the patients. After a follow-up of 1 year, one patient (the one with partial relief) was lost to follow-up. Five out of seven patients had significant relief, and 5/6 patients had sustained relief on long-term follow-up. No adverse effects were reported by any of the patients.

Conclusion:

The DEW technique is promising in providing significant relief in patients with MGD. The encouraging results of DEW in this series can help prescribe and extend the indications of DEW in managing MGD and other eye disorders, in which eye hygiene plays a therapeutic role and as a daily routine eye-care practice to prevent various eye disorders.
Clinical evaluation of capsule BP Norm in the management of essential hypertension: A preliminary open-label parallel group study
Authors: Tanna Ila Revachand , Goyal Mandip , Chandola Hari Mohan
Published: August 2024

Background:

Since hypertension is so common and a major risk factor for cardiovascular illnesses and other complications, it is both a significant public health issue and an important topic of research. Hence, a clinical trial was planned.

Aims:

To evaluate the role of herbal preparation capsule BP Norm containing dry extract of Bhringraja (Eclipta alba (L) Hassk.), Haritaki (Terminalia chebula Retz.), Ashwagandha (Withania somnifera (L.) Dunal), Shankhpushpi (Convolvulus pluricaulis), and Sarpagandha (Rauwolfia serpentina [L.] Benth. Ex Kurzc) in newly diagnosed cases and in combination with allopathic antihypertensive drugs in the uncontrolled cases of essential hypertension.

Materials and methods:

A total of 103 patients meeting the seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure criteria of essential hypertension (EHT) of age group 20–65 years of either sex participated in the study. Newly diagnosed cases who were not taking any antihypertensives were administered capsule BP Norm (250 mg), two capsules twice daily for 1 month, whereas uncontrolled cases of essential hypertension (systolic blood pressure [SBP] >140 mmHg and <200 mmHg and/or diastolic blood pressure [DBP] >90 mmHg and <120 mmHg) were administered 1 capsule of BP Norm (250 mg) twice daily with water in addition to continuing allopathic antihypertensive drugs for 1 month. The assessment was made through various variables such as SBP, DBP, chief complaints, associated complaints, Hamilton anxiety rating scale (HARS), Hamilton rating scale for depression (HRSD), lipid profile, and serum creatinine.

Results:

Capsule BP Norm produced highly significant reduction in both the SBP (16.82%, P < 0.001) and DBP (13.71%, P < 0.001) of newly diagnosed patients as well as in the SBP (18.49%, P < 0.001) and DBP (13.95%, P < 0.001) of uncontrolled cases (EHT). Capsule BP Norm provided significant relief in clinical features of EHT, HARS, and HRSD in both groups.

Conclusion:

Capsule BP Norm has promising antihypertensive effects in newly diagnosed cases as well as synergistic effects when combined with allopathic antihypertensive drugs in uncontrolled cases of essential hypertension.
Assessment of endothelial cell density after deep anterior lamellar keratoplasty
Authors: Ebied Ahmed H. , Khalil Hossam-Eldein M.A. , Haroun Hazem E. , Elbeih Islam F.A. , Saif Ahmed T.S.
Published: August 2024

Background

The fundamental aim of successful Keratoplasty is to obtain a clear corneal graft and to maintain its survival. Previous studies have demonstrated the importance of endothelial cell density (ECD) in maintaining graft transparency and survival after keratoplasty.

Objective

This study aimed to assess the changes in corneal ECD following deep anterior lamellar keratoplasty (DALK) and to evaluate its visual and surgical outcomes.

Patients and methods

This prospective observational study was conducted at the National Eye Institute Rod-Elfarag, Cairo, Egypt, between July 2020 and February 2022. It included 50 eyes of 50 patients, with pathologies affecting the epithelium and/or stroma for whom DALK was performed. Patients with comorbidities affecting the endothelium were excluded from the study. Preoperative, intraoperative, and postoperative data, including ECD, were collected. Postoperative assessments were conducted at 1, 3, and 6 months.

Results

The mean age of the patients was 24.80±2.81 years (range=21–30 years), with 60% of the patients being males. The preoperative diagnoses included keratoconus, granular dystrophy, macular dystrophy, and corneal scarring. The ECD significantly decreased from a baseline value of 2726.6±188.53 cells/mm2 to 2591±175.79 cells/mm2 at 1 month, 2461.3±155.43 cells/mm2 at 3 months, and to 2349.9±104.58 cells/mm2 at 6 months postoperatively (P<0.001). The best corrected visual acuity improved significantly from a preoperative value of 0.06±0.02 to 0.61±0.15 at 6 months, postoperatively (P<0.001). The postoperative complications included a double anterior chamber (in 2 eyes) and wrinkling of Descemet’s membrane (in 2 eyes).

Conclusion

DALK led to a significant reduction in ECD over the first 6 months postoperatively, with improvement in best corrected visual acuity. The study highlights the importance of considering ECD changes and visual outcomes in DALK patients. Preservation of the patient’s endothelium may contribute to better long-term outcomes, with careful consideration of the potential complications.
Exploring Ultra-short Heart Rate Variability Metrics in Patients with Diabetes Mellitus: A Reliability Analysis
Authors: Srivastav Shival , Gadhvi Mahesh Arjundan , Shukla Ravindra Gayaprasad , Bhagat Om Lata
Published: August 2024

Objectives:

Ultra-short heart rate variability (HRV) metrics represent autonomic tone parameters derived using small epochs of interbeat interval data. These measures have risen in popularity with the advent of wearable devices that can capture interbeat interval data using electrocardiography (ECG) or photoplethysmography. Autonomic neuropathy in diabetes mellitus (DM) is well established, wherein 5-min HRV is conventionally used. Ultra-short measures have the potential to serve as markers of reduced autonomic tone in this patient population.

Methods:

Data of patients with Type I and Type II DM who had presented to our laboratory for autonomic neuropathy assessment were chosen for analysis. One-minute and 2-min epochs were chosen from 5 min of ECG data using standard software. Time domain, frequency domain, and nonlinear measures were computed from 1 to 2 min epochs, and reliability was compared with measures derived from 5-min HRV using intraclass correlation coefficients (ICCs).

Results:

Data of 131 subjects (79 males, 52 females; mean age = 53.3 ± 12.16 years) were analyzed. All ultra-short HRV measures derived from 1 min to 2 min data showed good to excellent reliability (median ICC values ranging from 0.83 to 0.94) when compared with 5-min metrics. The notable exception was very low frequency (VLF) power, which showed poor reliability (median ICC = 0.43).

Conclusions:

Ultra-short HRV metrics derived from 1 to 2 min epochs of ECG data can be reliably used as predictors of autonomic tone in patients with DM. VLF power is poorly reproducible in these small epochs, probably due to variability in respiratory rates. Our findings have implications for ultra-short HRV estimation using short epochs of ECG data.
Pattern of velopharyngeal valve closure in patients with cleft palate after primary cleft palate repair: A cross-sectional nasoendoscopic analysis
Authors: Adamson Olawale Olatunbosun , Egbunah Uchenna Patrick
Published: August 2024

Background:

The velopharyngeal valve (VPV) consists of the velum, lateral pharyngeal walls, and posterior pharyngeal walls. Velopharyngeal (VP) closure is required during attempted phonation, deglutition, and sucking, and serves to prevent nasal regurgitation of fluids or solids that are normally delivered to the oropharynx.

Objectives:

This study aimed to identify the patterns of VPV closure in children with cleft palate (CP) who had palatal repair done and to determine the relationship between surgical technique and pattern of closure.

Patients and Methods:

This study was conducted in the nasoendoscopy room of the Orofacial Cleft Clinic, Lagos University Teaching Hospital. All patients with nonsyndromic cleft lip and palate or isolated CP who had palatal repair done at age 12 months and above with either von Langenbeck, Bardach, or Furlow’s techniques were included in this review. All patients were examined using a flexible fiber-optic nasoendoscope.

Results:

There were 35 patients who had nasoendoscopy done and met the inclusion criteria. The most common pattern of closure of the VP mechanism in patients examined by nasoendoscopy was circular (48.6%), followed by coronal (37.1%). von Langenbeck’s technique had the highest frequency in all patterns of closure though this was not statistically significant (P = 0.47). Both von Langenbeck and Bardach techniques had both coronal and circular as their most common closure patterns, while Furlow’s had the circular as the most common pattern of closure.

Conclusion:

The most common pattern of closure of the VP mechanism in patients who had CP repair in this study was circular and there was no apparent relationship between the surgical technique of repair and pattern of closure.
Analysis of phenotypic characteristics and mutation patterns in syndromic craniofacial anomalies: Insights from a tertiary care medical genetics unit in South India
Authors: Aaron Rekha , Chellappa Roopa Kunthavai , Danda Sumita
Published: August 2024

Context:

Craniofacial anomalies (CFAs) are rare congenital anomalies that have a profound impact on social acceptance. Most of the syndromic CFAs are genetic in origin and are the result of alteration in single or multiple genes inherited from parents or de novo.

Aims:

The main aim of this study was to explore the phenotypic variations and the mutation profiles in the various CFA.

Subjects and Methods:

This was a retrospective study where records of 20 patients were obtained from electronic medical records for analysis. The numbers provided do not accurately reflect the true prevalence as they only encompass cases referred to our department for testing.

Results:

The median age in this cohort was 1 year with males 60% and females 40%. Out of 20 cases, 8 cases were classified as CFA-associated craniosynostosis and 12 with orofacial clefts. Disease-causing genes identified were FGFR2, RTTN, ASXL3, IRF6, TP63, POLR1D, TCOF1, KMT2D, KDM6A, LARP1, and C5orf42. Most of these craniofacial syndromes were predominantly autosomal dominant, sporadic, and de novo. We had three autosomal recessive cases (RTTN, LARP1, and C5orf42) and one X-linked dominant case (KDM6A). Two novel variants were identified, one for Van der Woude syndrome and another for Crouzon’s syndrome.

Conclusions:

Although these syndromes are rare in occurrence, the present study provides a detailed phenotypic spectrum and causative mutation in various CFAs in Indian patients. This is crucial for understanding the genetic basis of these conditions and can potentially lead to advancements in diagnosis, treatment, and appropriate genetic counseling.
Arrhythmogenic Cardiomyopathy: Focus on Imaging
Authors: Shukla Madhu , Burkule Nitin , Agrawal Vinayak , Mohan Jagdish Chander
Published: August 2024

Arrhythmogenic cardiomyopathy (AC) is a broad term denoting subclinical or clinical heart muscle disease which presents predominantly with serious arrhythmias. Heart muscle disease or cardiomyopathy can present as an abnormal electrocardiogram, heart failure, syncope, arrhythmias, or sudden cardiac death. Ventricular arrhythmogenesis is the hallmark of this entity. A small but significant number of athletes experiencing sudden cardiac death have AC. AC has complex and ill-understood pathophysiology. Usually, arrhythmogenic cardiomyopathies are genetic or hereditary. In these patients, muscle hypertrophy, dilatation, cardiac fat metaplasia, and fibrosis provide the anatomic substrate for arrhythmias. Hereditary cardiomyopathies are considered primary diseases of the cardiac myocytes and their intercellular junctions. Secondary diseases of the myocardium due to coronary artery disease, hypertension, valvular heart disease, etc., are excluded from this nomenclature. Channelopathies are also not included in the spectrum of AC. Initially, AC was reported as a single phenotype and labeled arrhythmogenic right ventricular dysplasia, and it was considered a desmosomal disorder. Our current knowledge about this entity has expanded to include multiple variants of this entity with diverse genetic mutations. Its genotypes and phenotypes are still evolving. As of now, distinct desmosomal, cytoskeletal, nuclear, and sarcomeric ACs have been reported. Geography-specific syndromic ACs have also been described. It is a cell-to-cell disjunction cardiomyopathy impairing the inter- and intracellular signal transduction. Gap junctions make AC unique in the sense that arrhythmias precede structural alterations or heart failure in the vast majority. There is also a distinct arrhythmogenic atrial cardiomyopathy. Diagnostic algorithms include morphofunctional, depolarization and repolarization abnormalities, distinct genetic mutations, and typical arrhythmias which serve as the basis of scoring systems devised to diagnose AC. This review discusses salient aspects of AC focusing on imaging observations.
Delivering Integrated Care for Older People – A Feasibility Study on Online Training of Master Trainers
Authors: Kuba Ruchika , Singhal Sunny , Mathur Arvind , Goyal Laxmi Kant
Published: August 2024

Introduction:

The World Health Organization has advocated the training of healthcare workers in providing integrated care for older people (ICOPE). Due to physical and financial barriers, training through online mode was adopted. The aim of this study was to evaluate the acceptability, feasibility and effectiveness of the online ICOPE training programme.

Subjects and Methods:

It was an observational study and 102 doctors from seven South Asian countries were imparted ICOPE training online. Knowledge was tested through multiple-choice questions. Feedback was taken through a structured online questionnaire after each session and after 1 year.

Results:

About 88.4% found the session satisfactory to excellent for grasping the concept. Seventy-nine per cent of participants rated the session interaction to be satisfactory to excellent. About 91.8% of participants rated the utility of the session as satisfactory to excellent as a future master trainer. Participants demonstrated significant improvement in knowledge post-training (mean difference of 3.6 ± 2.8; P < 0.001). Post 1-year responses remained positive with 91.3% using the course materials and skills, and 82.6% providing further training to other doctors.

Conclusions:

The online training programme is feasible and effective in imparting ICOPE training.
Need to go Beyond Iron Supplementation for ’Anaemia Mukt Bharat’ amongst Children Under 19 Years – An Ecological Study
Authors: Chinnadurai Aravinda , Raja Sangeetha
Published: August 2024

Introduction:

Anaemia remains a prevalent issue in India, especially amongst the reproductive age group. This study was conducted to assess the contribution of micronutrient deficiencies beyond iron to this problem.

Materials and Methods:

Using data from the Comprehensive National Nutritional Survey 2016–2018 and key indicators from the Anaemia Mukt Bharat programme, we evaluated the role of micronutrient deficiencies in anaemia prevalence.

Results:

Our findings indicate that deficiencies in Vitamin A, B12, D, Zinc and folate significantly contribute to anaemia prevalence. In addition, the coverage of iron supplementation was low across many states and union territories.

Conclusions:

The current strategy of iron supplementation alone is insufficient. A broader approach, including multiple micronutrient supplementations, is necessary. The implementation of the AMB programme requires introspection with a focus on consistent drug supply and behavioural change campaigns in schools and Anganwadis.
Serious Adverse Events Following COVID 19 Vaccination in India: A Retrospective Study
Authors: Punathukandi Sruthikrishna , Thayyil Jayakrishnan , Nair Meera S. , Salam Ahana
Published: August 2024

Introduction:

The aim of this study was to identify the type and detail the serious adverse events following COVID-19 vaccination in India.

Materials and Methods:

The descriptive study was conducted by extracting the data from the website by the Ministry of Health and Family Welfare, Government of India https://shorturl.at/imwJY. The variables analysed were types of vaccines, types of SAEFI, thromboembolic (TE) events, neurological manifestations and consistent causal association as per the World Health Organization. Data were entered into MS Excel and analysed using the SPSS software version 25.

Results:

Out of the total 1.9 billion doses of COVID-19 vaccines, 1527 cases of SAEFI were reported. Among these, 51.7% were coincidental and 30.8% were associated with vaccination. All the allergic reactions (58), anaphylaxis (50), TE events (342) and Guillain–Barre syndrome (41) had consistent causal association. Out of the 598 deaths, 2% of deaths had consistent causal association. In comparison of exposure to Covaxin, Covishield had high odds of death (odds ratio [OR] =1.5; 95% confidence interval [CI] =1.11–2.07), acute febrile illness (OR = 2.07; 95% CI = 1–4.3), TE events (OR = 1.58; 95% CI = 1.08–2.31) and cardiovascular events (OR = 2.03; 95% CI = 1.32–3.13).

Conclusions:

Compared to other countries, similar types of SAEFIs were reported from India but at a lower rate.
Juxtapapillary congenital hypertrophy of the retinal pigment epithelium: A report of two cases
Authors: Alshalan Hanan A. , Alsalamah Abrar K. , Nowilaty Sawsan R.
Published: August 2024

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) occurring in the juxtapapillary location is extremely rare. In this report, we describe two cases of juxtapapillary CHRPEs discovered incidentally in two patients and highlight their clinical and multimodal retinal imaging features that helped establish the diagnosis and differentiate the lesions from other juxtapapillary solitary pigmented lesions.
Embracing the Need to Learn About the Health Needs of Transgender People
Authors: Alderman Chris
Published: August 2024

Doubtlessly, transgender people face a serious raft of societal challenges as well as explicit health issues that will become even more pressing as they enter the later years of their lives. It is incumbent upon pharmacists and others in the health arena to take steps to position themselves as people who can make a genuine difference when that is needed, not only in the context of clinical care but also in the education of the coming generations of health care professionals.
Geriatric Pharmacotherapy Case Series: Clotting and Gender-Affirming Care
Authors: Mertz Amanda , Fair Collin , Pol Jason
Published: August 2024

Background A transfeminine patient is a 79-year-old with past medical history significant for type 2 diabetes mellitus, hypertension, gender dysphoria, chronic kidney disease, dyslipidemia, total left hip replacement, and recent provoked deep venous thromboembolism (DVT).
She was seen by a pharmacist in a primary care clinic after her discharge from a skilled nursing facility. The patient was experiencing symptoms of gender dysphoria after discontinuation of her estradiol in setting of her DVT. Assessment Her renal function was calculated
to ensure she was on appropriate dosing of her medications. Because her DVT was provoked, providers determined she would require only 3 months of anticoagulation. Her laboratory test results showed a subtherapeutic estradiol level and her estradiol was restarted. Additionally, aspirin was
being prescribed for primary prevention of atherosclerotic cardiovascular disease and was discontinued. Outcome She has significant improvement in her gender dysphoria symptoms with resuming her estradiol and now has a therapeutic estradiol level. She is tolerating her
direct oral coagulant well and reports good quality of life. Conclusion When reviewing medications for patients it is important to take several factors into account, including dose, appropriate indication, and patient preference. Pharmacists play a key role, through collaboration
with providers, in assessing these medication-specific factors. Estradiol was stopped in this patient because of her DVT, but given her DVT was provoked after a recent surgery, it was unlikely that estradiol was the cause of her clot. Weighing the risks and benefits for any patient is important
when determining what medications are appropriate to continue. Additionally, calculating renal function appropriately in a gender-non-conforming patients ensures appropriate and safe dosing.
The role of psychoeducation and yoga in reducing the burden of family caregivers of people with Alzheimer’s disease
Authors: Araujo Edivaldo Lima de , de Brito Marcelo Gonçalves
Published: August 2024

The continuous increase in the elderly population and chronic health conditions present significant challenges to healthcare systems, particularly in developing countries. Among these conditions, dementia, particularly Alzheimer's disease (AD), is one of the most concerning, causing cognitive decline, behavioral changes, and progressive dependence on family caregivers. The physical, emotional, and financial burden on caregivers can deteriorate their quality of life. Psychoeducation has shown efficacy in reducing stress and improving caregiving skills. Yoga-based approaches have also demonstrated significant benefits in reducing symptoms of anxiety and depression. This commentary aims to describe the effect of psychoeducation and yoga in reducing the burden on family caregivers of people with AD, primarily exploring the findings of the study by Araujo et al. (2023). In this study, psychoeducation was effective in reducing caregivers' burden, while the integration of yoga improved only certain aspects of quality of life. The research indicates that distance learning methodology is feasible, cost-effective, and can assist caregivers. However, the short duration and frequency of the yoga sessions may have limited their effects.
Modeling of psychological time cognition with Human Language based Consciousness model
Authors: Hebishima Hana , Inage Shinichi
Published: August 2024

This paper interprets subjective psychological time in a model of consciousness called the HLbC model proposed by the authors. Time has an objective physical time and a subjective psychological time. Subjective psychological time is thought to vary in its flow depending on the individual and the situation. For this explanation, this paper introduces surreal numbers into the perception of subjective psychological time. A surreal number is a number determined from two sets of different magnitudes and contains various temporal features, including the second law of thermodynamics. By this introduction, it is shown that subjective psychological cognition is reduced to the information entropy of the present and the past by the individual or the state of each individual and depends on the state of the information entropy.
Renal rehabilitation: Recommendations of exercise therapies in patients with kidney diseases
Authors: Koley Shyamal
Published: August 2024

Renal rehabilitation is a process to conduct treatments for the patients suffering from kidney disease and support to help them for their smooth achievement of social rehabilitation. Patients with dialysis-dependent kidney failure carry some additional burden of co-morbidity, such as, diabetes mellitus, hypertension, cardiovascular disease, infections, and many other. Approximately 10% of the world population is affected by chronic kidney disease and the incidence of dialysis is quite high. The patients those undergoing hemodialysis are at increased risk of sarcopenia or frailty and serious health problems as compared to people with normal kidney function. Such complications lead to kidney transplantation and ultimately lead to adverse health outcomes such as functional dependence, hospitalization, and death. Exercise rehabilitation is a well established therapy in patients with kidney disease. Despite more than three decades of exercise research in patients with kidney disease, its applications were not very common in practice. It is only in recent days it gets some attraction. Thus, in the present study, an attempt has been made to elaborate the exercise therapies in renal rehabilitation.
DIABETES MELLITUS (MADHUMEHA ): AN AYURVEDIC REVIEW
Authors: Shamariya Minakshi , Kumar Mishra Pramod , Sharma Brahmanand , Sharma Indumati
Published: August 2024

One of the significant long-term health issues of the modern period is diabetes mellitus, which can lead to fatali-ties as well as severe long-term sequelae such as retinopathy, neuropathy, nephropathy, and heart disease. One of the major illnesses in which the amount and frequency of urination increase is called Madhumeha in Ayurve-da. Diabetes is a metabolic disease that causes insufficient or improper synthesis of insulin. Twenty different forms of Prameha are documented in Ayurveda, all of which share a similar symptomatology. It turns into Madhumeha if left untreated. One variety of Vataja Prameha is Madhumeha. Understanding Madhumeha's causes, risk factors, prevention, and treatment found in Ayurvedic literature helps treat Diabetic Mellitus.
A CRITICAL REVIEW OF THE CONTROVERSY OF ELAVALUKA AN AYURVEDIC
DRUG
Authors: - Vinod , B Karigar Shivananda , Bellamma Sampatkumar
Published: August 2024

Ayurveda is a traditional Indian system of medicine. In the present era, the world is looking towards herbal med-icine because of its acceptability and safety. Medicinal plants constitute an effective source of Ayurvedic and another traditional system of medicine as well as modern medicine. About 80% of India’s rural population de-pends on herbal medicines at the primary health care level. A large percentage of plants used in herbal industries are subject to controversy. The non-availability of plants, poor understanding, and parallel evolved knowledge systems are some of the reasons for this. The existing practices of the polynomial nomenclature system of San-skrit, different perceptions in various communities, and vernacular equivalents are cumulative factors for contro-versy. Elavaluka is one of the controversial drugs used in many formulations like Kalyanaka ghrita, Maha-kalyanaka ghrita, Abhayaarista, etc. Elavaluka is promoted in Ayurvedic medicine for its purported benefits in treating various ailments, including inflammatory conditions, anxiety, schizophrenia and respiratory disorders. However, its composition and mode of action need to be well-documented in scientific literature, raising con-cerns about its safety and reliability. In conclusion, while Elavaluka remains popular in traditional Ayurvedic medicine, its controversial status necessitates further scientific scrutiny to address safety concerns and validate therapeutic claims effectively.
ANATOMICO-CLINICAL PERSPECTIVE OF SROTAS wsr to ARTAV VAHA SROTAS
Authors: Singh Preeti , Kumari Sunita , Saxena Sanjiv
Published: August 2024

Sharira is a form of innumerable ultramicroscopic units termed parmanu, which are configurated in a specific pattern to form a fundamental basic unit called cells. Srotas are micro-channels which provide a platform for the reactions and subsequently act as a channel for the transportation of the products formed in these reactions.so there
is a need to draw light that clinically, srotas can be treated as BIO –MARKER to find out the cause of a disease as
well as to manage the disease. This article is focused on establishing a clinical approach to evaluate Artavvaha
srotas and its moola according to the above phenomenon from an anatomical perspective.
AYURVEDIC MANAGEMENT OF CHRONIC MAXILLARY SINUSITIS- A SINGLE
CASE STUDY
Authors: - Barkha , Verma Kanchana , Khatana Rakesh , Khatana Anamika
Published: August 2024

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AN AYURVEDIC MANAGEMENT OF ALLERGIC RHINITIS (VATAJ PRAT-ISHYAY)- A SINGLE CASE STUDY
Authors: Rajpurohit Deepak Singh , Meena Prahlad , Kumar Mishra Pramod , Sharma Indumati
Published: August 2024

In contemporary society, the prevalence of diseases like Vataj Pratishyay (allergic rhinitis) significantly impacts
individuals both physically and mentally, disrupting daily life functions. Despite the increasing incidence of this
ailment, conventional medical systems struggle to provide an entirely successful cure. This clinical work aims to
address and eliminate this widespread societal issue. The clinical work involves an Ayurvedic postgraduate scholar who sought treatment for Vataj Pratishyay (allergic rhinitis) at the Kayachikitsa department of the DSSRAU
hospital in Jodhpur. Despite prior allopathic medication, the patient's condition persisted. Ayurvedic treatment,
including Agnitundi Vati (tablet) and Sanshamani Vati orally, Anu Tail (trans nasal drug) for Nasya (nasal administration), and dietary aversion, was administered for 45 days. Gradual discontinuation of allopathic medications
was undertaken. After completion of treatment, the patient was followed up at weekly intervals for three months.
The patient was completely cured of the disease, and there was no recurrence of the disease and no side effects
from the treatment. This clinical work taught us that Ayurvedic therapeutic management can effectively cure allergic rhinitis.
La ciberguerra: una aproximación conceptual
Authors: Garcia Latorre Yamil Fernando , Torres Gomez Yonnathan Jose
Published: August 2024

El objetivo general de esta investigación fue analizar algunas proposiciones teóricas sobre la ciberguerra y sus efectos en la dinámica venezolana. Se apoyó en el enfoque cuantitativo de tipo documental. Entre las conclusiones, resaltan que esta forma de ataque está dirigida a disminuir la capacidad del Estado – Nación que surgió con el tratado de Westfalia, en el cual nace el principio de soberanía sustentado en tres elementos que componen este principio; gobierno, población y territorio, generando situaciones de ingobernabilidad. el entorno de la información que se encuentra alojada en el ciberespacio es un dominio global que se caracteriza por estar conformado por redes independientes en las cuales es esencial la interoperatividad. Adicionalmente, la ciberguerra responde a las nuevas tendencias geopolíticas mundiales, en las cuales existe el interés, de la destrucción de la entidad del Estado-Nación como espacio para la soberanía nacional.
PERAN HUKUM ISLAM DALAM HARMONISASI HAK DAN KEWAJIBAN ASASI MANUSIA DALAM PERSPEKTIF PANCASILA
Authors: Paramitha Vallencia Nandya
Published: August 2024

In principle, Human Rights (HAM) are a basic right that is inherent in every human being because these rights are not a gift from a person, organization or state but are an invaluable gift from Allah SWT, but are priceless from Allah SWT. The concept of harmonization of Islamic law in realizing the implementation of human rights and obligations from a Pancasila perspective can bring good benefits to Indonesian society amidst the sensitivity of the problems occurring in Indonesia. This research examines the concept of human rights from Western and Islamic views and the role of Islamic law in realizing harmonization of human rights and obligations from the Pancasila perspective. This writing uses a type of normative research which is carried out by searching the literature which is then supported by additional data to strengthen this research. Using this normative research method will also help answer the concept of human rights according to Islamic law and the role of Islamic law in realizing harmonization of human rights and obligations from the Pancasila perspective. Results: It is important to remember that Islamic law and human rights cannot be separated absolutely. In Pancasila Law, these two concepts complement each other and must not conflict with each other. This is also in line with Islamic teachings which emphasize the importance of justice and balance in various aspects of life. This principle is in accordance with the teachings of the Islamic religion which emphasizes the importance of justice and equality in society. So, Islamic Law and Human Rights in Pancasila Law have the same goal, namely creating a just and equitable society. The conclusion of this writing is that the relationship between Islamic law and human rights in Pancasila Law is a complementary relationship and cannot be separated. Both have an important role in creating an Indonesian society based on Pancasila, so we must understand and appreciate these two concepts in order to live in harmony and balance in accordance with the nation's noble values.
The Importance of HSE (Health, Safety, And Environment) Communication on A Voyage
Authors: Handayani Hanifah , Masjuli Masjuli , Madhona Yenny Frisca , Amaliah Suci
Published: August 2024

The shipping industry is an important sector in the global economy. However, this industry also has high occupational safety and health (K3) risks. One of the efforts to minimize this risk is to communicate the HSE (Health, Safety and Environment). This research aims to analyze the importance of the role of HSE and its implementation in shipping. This research adopts a qualitative approach. The data collection technique used is a literature study. The data obtained was then analyzed through three stages, namely data reduction, data presentation, and drawing conclusions. The research results indicate that communication related to HSE in the shipping sector is crucial to creating a safe, healthy, and environmentally friendly work environment for all ship crew and passengers. Open and continuous HSE communication also plays an important role in building a strong safety culture in the shipping sector. Additionally, the benefits of HSE communications are not only limited to improving safety but also help ensure health in the workplace. This shows that effective HSE communication improves safety and health outcomes and supports overall productivity and well-being in the shipping industry, demonstrating its crucial role in sustaining operational excellence.
Analisis Hambatan Samping Jalur Satu Arah pada Ruas Jalan Agro (Segmen Perempatan Pos Polisi Bulaksumur Sampai Bunderan Perikanan UGM)
Authors: Subagyo Singgih
Published: August 2024

Jalan Agro adalah salah satu jalan yang ramai dan sering dilalui salah satu alasannya yaitu di samping jalan terdapat kampus, Toko Gudeg, dll, jalan ini mengalami ketidaklancaran kinerja arus lalu lintas akibat adanya parkir di badan jalan, oleh karena itu jalan ini menjadi lokasi penelitian terutama bertempat pada Jalan Agro arah barat ke timur segmen Perempatan Pos Polisi Bulaksumur sampai Bunderan Perikanan UGM. Tujuan penelitian ini adalah untuk mengetahui pengaruh aktivitas parkir pada badan jalan terhadap kinerja lalu lintas di Jalan Agro. Penelitian ini dilakukan melalui survei volume lalu lintas dan survei hambatan samping secara bersamaan. Hasil analisis kinerja ruas jalan didapatkan bahwa volume (Q) tertinggi lalu lintas yang ada di ruas Jalan Agro yaitu terjadi pada Hari Selasa sebesar 926 skr/jam, kerapatan (K) senilai 51,1 dan derajat kejenuhan (Dj) senilai 0,308, dan volume (Q) terendah lalu lintas yang ada di ruas Jalan Agro yaitu terjadi pada Hari Minggu sebesar 329 skr/jam, kerapatan (K) senilai 13,6 dan derajat kejenuhan (Dj) senilai 0,110 dengan indeks pelayanan terendah berada berada pada kategori B dan indeks pelayanan tertinggi berada pada kategori C. Dengan demikian dapat disimpulkan bahwa parkir pada badan jalan menyebabkan menurunya kapasitas ruas jalan yang berdampak pada menurunya kinerja ruas jalan.
Analisis Prediksi Prestasi Siswa UPTD SD Negeri 30 Aek Batu dalam Machine Learning dengan Metode Naive Bayes
Authors: Ambarita Mira Nanda , Nasution Marnis , Mutiah Rahma
Published: August 2024

This study aims to analyze and predict student achievement at UPTD SD Negeri 30 Aek Batu using a machine learning method with the Naive Bayes algorithm. By collecting data that includes academic grades, attendance, and other factors, the study cleans and processes the data to build a prediction model. The Naive Bayes algorithm is applied to identify patterns and relationships between these variables and student achievement. The results of this model are evaluated to determine its accuracy and ability to predict student performance, thereby providing valuable information for educational improvement strategies and interventions in schools.