bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of quality indicators and studying the stability of “Propolis-AK” gel for the treatment of acne disease
Authors: Tykhonov А. I. , Yarnykh T. G. , Bobro S. G. , Shpychak O. S.
Published: March 2019

In modern conditions, the incidence of acne, which is a polymorphic multifactorial disease of the sebaceous glands of the skin, has a tendency to significant growth. Localization of lesions on the face in almost all patients indicates the fact that acne has an effect on their psycho-emotional sphere and social adaptation, which makes this problem urgent and indicates the feasibility of creating new effective domestic medicines for treating this pathology.

The aim of the work was to conduct research on the investigation of quality indicators and studying the stability of «Propolis-AK» gel of anti-inflammatory and antimicrobial action for the treatment of acne disease.

The objects of research were model test-samples of «Propolis-AK» gel, for which were developed methodic for analyzing the qualitative composition and quantitative content of the active substances – propolis phenolic hydrophobic drug (PPHD) and azelaic acid (AA) in this dosage form, comprehensively allowing to evaluate the quality and criteria for the stability of the gel during the entire storage period for the following indicators: description, identification, homogeneity, tightness of the container, pH, package contents, microbiological purity, quantification. In addition, the requirements for packaging, labeling, transportation, storage conditions and shelf life were included in the draft of quality control methods.

According to the results of the study of organoleptic and physical-chemical parameters of the developed «Propolis-AK» gel during storage at two temperature conditions (8‒15 °C and 15‒25 °C), it was found that the test samples of the gel under study remained fairly stable according to the studied indicators for 2 years and 3 months, which allows us to recommend a shelf life of 2 years at room temperature in aluminum tubes for the studied gel. According to the results of research, a specification for «Propolis-AK» gel for external use was developed as a component of the draft of quality control methods for the studied medicine.

Studies have been conducted to establish the main indicators and methods of quality control of the developed «Propolis-AK» gel for the treatment of acne disease. According to the results of the tests, a “Specification” was developed, which was included in the draft of quality control methods and experimentally proved the stability of «Propolis-AK» gel prepared in pharmaceutical and industrial conditions for a prescribed shelf life of 24 months when stored in aluminum tubes with an internal lacquer coating in a cool place (8‒15 °C) and at room temperature (15‒25 °C).
HPLC-determination of active components in dietary supplement «L-CARNITINE smart»
Authors: Voitiuk O. D. , Yegorova A. V. , Scrypynets YU. V. , Kashutskуy S. N. , Kluchnik O. G. , Umetskaya I. V.
Published: March 2019

Dietary supplements are compositions of biologically active substances intended for consumption with food or addition to food products for the purpose of optimization of metabolic processes and functions of the human body. The dietary supplements include: vitamins, trace elements, amino acids, enzymes, proteins, probiotics, oils that can provide antioxidant, detoxifying, immunomodulatory, adaptogenic effects, etc.

Detection of physiologically active components in dietary supplements is a difficult task and requires the use of modern highly informative research methods. One of the most powerful and versatile methods of determination is the method of high performance liquid chromatography (HPLC), combining the selective separation of the studied mixtures and high sensitivity.

The purpose of this study was to develop a simple, rapid and selective method for determining ascorbic acid and L-carnitine L-tartrate in a multicomponent dietary supplement, produced in the form of sachets, using HPLC with spectrophotometric detection.

The object of the study is the dietary supplement «L-CARNITINE smart», powder for oral solution of 16 g each in a sachet (INTERСHЕM). For the quantitative determination of the applied method of high-performance liquid chromatography. Chromatography was performed on an Agilent 1260 Infinity 2D LC System (USA) liquid chromatograph with a UV detector.

The optimal conditions for the analysis have been experimentally determined: the type of sorbent, the composition of the eluent and its gradient, the wavelength and the detection time for ensuring the release of all components (including auxiliary substances) from the column, selective separation of ascorbic acid, potassium acesulfame and L-carnitine L-tartrate, minimization analysis time. The method has been validated according to the following parameters: specificity, linearity, accuracy, limit of quantitation.
Synthesis and establishment of physico-chemical constants 2-(5-( chinoline -2-il, 2-hydroxyquinoline-4-іл)-4-R1-1,2,4-triazole-3-ілтіо) acetate acids and their esther
Authors: Kaplaushenko Т. М. , Panasenko О. І. , Samelyuk Y. G.
Published: March 2019

The large interest in the plan of search biologically of active agents is caused by the heterocyclic system of 1,2,4-triazole, due to high biological activity, and by the low indexes of toxicness, that inherent it to the structural analogues. Today in medical practice the derivatives of 1,2,4-triazole are used as high-efficiency antioxidants, cytostatic antimycotic agent , antidepressants and others.

Literary information testify that among connections, representatives derivative of 3-tio-1,2,4-triazole range condensed with heteryl carboxylic acid, and their derivatives, find matters with the wide spectrum of biological action.

The primary purpose of this work is continuation of synthetic researches 5-(chinoline-2-il, 2-hydroxyquinoline-4-il)-4-R1-1,2,4-triazole-3-tion, namely synthesis of new 2-(5-(chinolin-2-il, 2-hydroxyquinoline-4-il)-4-R1-1,2,4-triazole-3-iltio) acetate acids, their esteriv and establishment for the new structural derivatives of physical and chemical constants, confirmation of structure and individuality.

On the basis of purposeful synthesis was received 10 new, connections derivatives of 1,2,4-triazole not described in literature, that contain the kernels of triazole`s cycle of chinole in a 5 position, or 2- hydroxyquinoline deputies, namely 2-(5-(chinoline-2-il, 2-hydroxyquinoline-4-il)-4-R1-2,4-dihydro-3Н-1,2,4-triazole-3-iltio) acetate acids and their esteras. For the synthesized connections by the modern physical and chemical methods of analysis their structure is well-proven, and physical and chemical constants are set.

Structure of synthesized esteriv 2-(5-(quinoline-2-il, 2-hydroxyquinoline-4-il)-4-R1-1,2,4-triazole-3-iltio) of acetate acids is confirmed the complex use of element analysis and ICh-spectrophotometry.
Development and validation of the method for determination of encapsulation efficiency of cytochrome c in liposomes
Authors: Katsai O. G. , Prokhorov V. V. , Grigorieva G. S. , Krasnopolsky Yu. M.
Published: March 2019

A strategic pathway in creating high-potent medical products is with targeted therapeutic systems that are based on nanoparticles of various structure. Such particles are capable of providing a targeted effect and an increase in bioavailability of the medical products. A special place among modern targeted drug delivery systems is held by liposomal nanoparticles which have apparent advantages over nanoparticles of an another type The problem number one for pharmacy lies in developing specific methods of control of nanosize drug delivery systems.

This research is dedicated to the development and validation of a technique for determining encapsulation efficiency of cytochrome C in liposomes.

The subject of research comprised the obtained liposomal form of cytochrome C, placebo emulsion, and cytochrome C solution. The research was conducted in compliance with the ICH and FDA requirements and recommendations in relation to the development of HPLC methods of control of liposomal preparations.

A method has been developed to enable the determination of encapsulation efficiency of cytochrome C in liposomal preparations and to allow for identifying the composition of liposomal nanoparticles of cytochrome C. This HPLC method has been validated in terms of specificity, limit of detection, and robustness in compliance with the recommended criteria. The technique may find its application in quality control of liposomal form of cytochrome C and in control points manufacturing process.
Research of acute toxicity of the drug HEXIA
Authors: Karbovskyy V. L. , Shevchuk I. A. , Kurkina O. V. , Makovska T. Ye.
Published: March 2019

Diseases of the genitourinary system caused by pathogenic and potentially pathogenic microorganisms, which result into disbiosis of urinary organs, remain an urgent problem of dermatovenereology, gynecology and urology, despite the fact that there is a significant number of available and new medicines to treat them.

The aim of the work was to determine the safety of the preparation Hexia within experiments on animals.

The acute toxicity of Hexia has been determined on 20 adult female laboratory rats under the conditions of hourly intravaginal administration of the preparation with a dose of 70 mg/kg during 12 hours, as well as on 20 female laboratory rats and 20 female laboratory mice with a single intragastric administration in a dose of 145 mg/kg. The assessment of the impact of the preparation studied was performed on the basis of the following parameters: a) mortality (terms of death of animals in each group, on a daily basis); b) assessment of toxicity development (on a daily basis), including an assessment of the visual environment of the area of injection (the presence of irritation, redness, edema); c) dynamics of body weight changes (in the initial state, on the 4th, 7th and 14th day after application); d) macroscopy of internal organs, mass coefficients of internal organs within rats (on the 14th day).

It has been found that intravaginal application and a single intragastric administration of the preparation Hexia in the form of pessaries, which contain chlorhexidine digluconate, does not result into death of rats and mice, brings no effect on body weight gain, integrative parameters of the functional state of laboratory animals as well as on the relative mass of internal organs, which implies the absence of significant toxic effect of the preparation. Thus, the results of the studies conducted indicate that the median lethal dose for Hexia in case of intravaginal application to rats or intragastric administration to rats and mice is beyond the rate of 500 mg/kg. According to the toxicological classification of substances Hexia belongs to the IV class of toxicity – low toxic substances.
Kedudukan Hukum Penggunaan Pasal Percobaan Perzinahan Dalam Praktik Peradilan
Authors: Alfiantoro Handoko
Published: March 2019

Kedudukan hukum terhadap penggunaan suatu pasal, berkaitan erat dengan eksistensi tentang dapat tidaknya suatu pasal tersebut bisa diterapkan. Tidak terkecuali terhadap kejahatan terhadap perkawinan berupa tindak pidana perzinahan yang seringkali menjadi persoalan. Adanya kekhasan pengertian tentang perzinahan menurut hukum dengan kompleksitas syarat-syarat pengaduan perzinahan yang relatif panjang membuat penyelesaian perkara tindak pidana perzinahan tidak cepat berjalan. Persoalan lain kemudian muncul ketika voltoid delict dalam pasal tindak pidana perzinahan belum sampai selesai dan dimasukkan dalam kategori percobaan. Batasan formulasi yang belum tegas tentang percobaan perzinahan, serta perbedaan penafsiran tentang permulaan pelaksanaan dan perbuatan persiapan membuat penggunaan pasal percobaan perzinahan seringkali menjadi bahan perdebatan. Artikel ini disusun dengan menggunakan metode penelitian yuridis normatif melalui pendekatan undang-undang, pendekatan perbandingan dan pendekatan konseptual, yang bertujuan untuk mengkaji secara kritis tentang Kedudukan Hukum Penggunaan Pasal Percobaan Perzinahan Dalam Praktik Peradilan.
КВАЗАРИ І ТЕМНА МАТЕРІЯ
Authors: Нарожный Анатолий Николаевич
Published: March 2019

Two problems related to quasars are considered. The first is the energy of quasars, which is considered one of the most serious problems of active galactic nuclei. The second is redshifts in their emission spectra. To ensure the "work" of the quasar, in addition to the energy coming from the accretion disk, its additional sources are needed. One such source is given, and it is associated with a large amount of dark matter in galaxies. However, the energy released during the destruction of the particles of the dark component is the energy of the microwave range, and it only partially solves the energy problem of the quasar. Therefore, there is a need for another and more powerful source of energy, as well as a related mechanism capable of converting microwave radiation into high-energy radiation. The importance of such a source is also indicated by the second energy feature of quasars. It is associated with the presence of some of them very high speeds of motion of matter in jets. In this case, the flow rate of matter in a jet can exceed the speed of light in a vacuum several times. Such a source of energy is indicated, but not analyzed. In addition, for quasars with jets, the presence of large and extremely contradictory redshifts in their spectra is characteristic. This applies to both emission spectra and absorption spectra. From the standpoint of the officially accepted concept of an “expanding universe,” these unusual shifts of radiation cannot be explained. Interpretation of redshifts in quasar emission spectra based on the interaction of radiation and dark matter (“energy loss by radiation”) is given. This approach to the interpretation of the red shift in the spectra of quasars covers many questions, but not all. Within its framework, it is not possible to explain the origin of “quantized” redshifts in the spectra of galaxies, discovered by V. Tifft and confirmed by H. Arp. The excessively weak positions of the red shift in the spectra of quasars are indicated as a physical parameter characterizing the distance to the radiation source.
Analog Multiplier Based on Squarer Cells
Authors: Zarei Reza , Maali Moora
Published: March 2019

In this paper, a current-mode analog multiplier circuit is proposed that utilizes MOS translinear principle. The parameters of TSMC 0.18µm technology are used to design the proposed multiplier that employs CMOS transistors operating in weak inversion region. Simulations are performed by HSPICE for the circuit to prove its great merits of; low power consumption (100µW), low supply voltage (1.6V), body effect immunity, wide input range (±100nA), bandwidth of 1 MHz, and THD of 4%.
Interações Medicamentosas na Farmacoterapia de Idosos com Câncer atendidos em um Ambulatório de Onco-Hematologia
Authors: Faria Caroline de Oliveira , Reis Cristiane Moreira , Santos Andrezza Gouvêa , Reis Adriano Max Moreira
Published: March 2019

Introdução: Mais de 50% dos diagnósticos de câncer ocorrem na população idosa. Esse grupo etário possui outros problemas de saúde concomitantes à neoplasia que aumentam o risco de polifarmácia e interações medicamentosas. Objetivo: Identificar a frequência das interações medicamentosas potenciais e analisar os fatores associados na farmacoterapia de idosos com câncer. Método: Estudo transversal realizado em um ambulatório de onco-hematologia de um hospital de ensino. Foram entrevistados 160 idosos submetidos à terapia antineoplásica parenteral. Registraram-se informações sobre farmacoterapia, diagnóstico da neoplasia, outros problemas de saúde e funcionalidade. A funcionalidade foi determinada usando o Vulnerable Elders Survey. As informações clínicas foram coletadas em prontuário. Identificaram-se interações medicamentosas potenciais empregando o software Drug Interaction Checking. A regressão logística foi utilizada para determinar os fatores associados às interações medicamentosas potenciais. Resultados: Noventa e sete (60,6%) idosos apresentaram pelo menos uma interação medicamentosa e 42 (26,3%), interação envolvendo um medicamento antineoplásico. Ciclofosfamida e fluouracila foram os mais envolvidos em interações. O mecanismo farmacodinâmico foi responsável por 52,5% das interações. Identificou-se que 51% das interações foram classificadas como graves. A regressão logística mostrou que interações medicamentosas estiveram associadas de forma independente com número de medicamentos [OR=1,51; IC95% (1,277-1,78), p<0,0001) e de problemas de saúde [OR=1,39; IC95% (1,030-1,880), p=0,031]. Conclusão: A frequência de interações medicamentosas potenciais em idosos com câncer em terapia antineoplásica parenteral foi elevada, ainda que a proporção de interações graves corresponda à aproximadamente metade do total deinterações. O número de problemas de saúde e o de medicamentos apresentaram associação positiva com interações medicamentosas.
On Licensing the Technology of Small Modular Reactors
Authors: Dybach О. , Plachkov H.
Published: March 2019

There has been a steady growth of interest in the technology of small modular reactors (SMR) in the world recently. SMRs are considered as a promising area for the further development of nuclear industry. The paper defines the term “small modular reactor”, presents the scope, potential advantages and disadvantages of SMR. A review was made and a classification of SMR projects was proposed depending on the novelty of their technical solutions. The paper presents an enlarged comparative analysis of individual SMR technical solutions (based on the example of Holtec International SMR-160) with operating Ukrainian NPPs to identify peculiarities of SMR that should be addressed in licensing. Certain specific design solutions of SMR-160 are correlated with defense-in-depth levels. The approaches and condition for licensing SMR designs in the international practice are analyzed. The paper identifies problematic aspects with regard to regulatory framework and confirmation of the efficiency of SMR design solutions, as well as formulates proposals and recommendations for the first steps to ensure the licensing process in response to the initiative of the operating organization Energoatom.
Analysis of Reliability-Critical Hydraulic Impact Conditions at WWER-1000 NPP Active Safety Systems
Authors: Skalozubov V. , Kozlov I. , Chulkin O. , Komarov Yu. , Piontkovskyi O.
Published: March 2019

An original method to determine the onset of conditions for reliabilitycritical hydraulic impacts for reliability analysis of active safety systems of nuclear power installations is proposed. The suggested method is based on determining the effect of head-flow characteristic delay onto hydraulic impact preconditions during the changes of pipeline system hydrodynamic parameters under transitional modes (e.g. in pump start-up). The delay time of responses to change in the hydrodynamic system parameters embodies the determining factor of head-flow characteristic’s inertance, depending on both design and technical parameters of system components (including pumps), and the hydrodynamic parameters change rate under transitional modes. Using the proposed method, the analysis of conditions for critical hydraulic impacts is performed for the primary high-pressure safety injection system of serial WWER-1000 nuclear power plants. The analysis results allow a conclusion that for this system the conditions leading to hydraulic impact due to the pump start are not reached. The developed method can be applied to any thermal and nuclear power facilities’ pipeline systems equipped with pumps.
Mobile technologies in the professional training of students of economic specialties
Authors: Osadchyi Viacheslav
Published: March 2019

Representatives of economic specialties must have the skills to use modern information technology in their professional activities. One of these technologies is mobile, based on the use of mobile devices, services and mobile communications. The purpose of the study is to analyze the opportunities and prospects of mobile learning in the process of professional training of students of economic specialties. In order to study the prospects of introducing mobile technologies into the process of professional training for students of economic specialties in mobile app stores, analysis of applications for the platforms of Google Android and Apple iOS was conducted. Mobile applications have been identified which can be used in the process of training students of economic specialties in terms of content and functionality. They were assigned to the following groups: e-books, directories and dictionaries, news editions, manuals and manuals for economists, simulators of economic processes, appendices for learning a foreign language, question sets and simulators for passing the tests on economics, simulators for work with accounting programs, economic courses, economic calendars, economic calculators, financial monitoring applications, business plans and business ideas, notebooks and planners. As a result of a survey of teachers and students, it was concluded that all interviewed have mobile phones and use mobile Internet. In the educational process, mobile applications use 70% of teachers and 97% of students, including special programs of economics using 50% of teachers and 93% of students. Of the applications of economic orientation, most teachers use manuals for economists (70%) and directories and dictionaries (70%), most students - directories (77%) and training simulators for work with accounting programs (73%). Both lecturers and students indicated that they would like to use mobile applications of economic subjects in professional training. The results of the theoretical analysis and the survey give grounds to assert about the sufficient possibilities of available mobile technologies and the positive attitude towards their use in the professional training of students of economic specialties.
Pengaruh Inflasi, Kurs, Suku Bunga, dan Harga Minyak Dunia Terhadap Indeks Harga Saham Industri Pertambangan di Bursa Efek Indonesia Periode 2012-2015
Authors: Ningsih Yulia Istia , Muthmainnah Muthmainnah
Published: March 2019

This study aims to determine how the influence of inflation, exchange rates, interest rates, and world oil prices on the mining industry stock price index in the period 2012-2015. The object in the 2012-2015 research period is mining companies on the Indonesia Stock Exchange. The population used in this study were 31 mining companies and was based on a purposive sampling method which produced a sample of 11 companies. The dependent variable is represented by the mining industry stock price index, while the independent variables in this study are inflation, exchange rates, interest rates, and world oil prices. Partially the results of this study indicate that during the 2012-2015 period the variable exchange rates and world oil prices affected the mining industry's stock price index, while inflation and interest rates did not affect the stock price index mining industry. Simultaneously shows the influence of independent variables on the mining industry stock price index.
Analisis Pengaruh Tingkat Investasi, Pendapatan Asli Daerah dan Tenaga Kerja Terhadap PDRB Provinsi Jambi
Authors: AZ Siti Marlina , Pebrina Siska
Published: March 2019

Economic development is the process of changing the undeveloped economic structure by means of capital investment and human investment aimed at increasing the prosperity of the population or rising income per capita. The purpose of this study was to find out about the effect of the level of investment, local revenue, labor on the GRDP of Jambi Province. In this study using qualitative and quantitative approaches. The variables used in this study are independent variables, namely the level of investment, Regional Original Income and labor. The dependent variable is Gross Domestic Regional Income. Data analysis tool used multiple regression, T test, F test and determination. The results of the research show that the investment level is still low due to high economic licensing. The level of investment, PAD and labor has a significant influence seen from the joint test, namely the determination of 11.036. In the end, research was targeted so that the economy of Jambi province increased by facilitating all processes in licensing activities and increasing PAD
Analisis Pengaruh Pertumbuhan Ekonomi, Upah Minimum Provinsi Terhadap Kesempatan Kerja di Provinsi Jambi
Authors: Fauzani Evi
Published: March 2019

This study aims to find out and analyze the influence of economic growth, and provincial minimum wages on employment opportunities in Jambi Province. The data used are secondary data in the form of periodic data series (time series) which began from 2001 to 2016 obtained from government agencies and internet sites that have been further processed. The method of analysis used is qualitative descriptive analysis and quantitative analysis using multiple linear regression data processing is done by Microsoft Excel and Eviews Software programs. Based on the results of the simultaneous testing showed that all the independent variables obtained by economic growth and provincial minimum wages had a significant influence on employment opportunities, while in partial testing showed that economic growth had a significant effect on employment opportunities, and provincial minimum wages had a significant effect on employment opportunities.
Analisis Realisasi Penerimaan Pajak Reklame dan Pengaruhnya Terhadap Pendapatan Asli Daerah Kabupaten Batang Hari Periode 2006-2015
Authors: Rosmawati Sri , Rizqiah Fadhila
Published: March 2019

This research was conducted to find out how the development of Batang Hari Regency Advertising Tax revenue, how the Development of Batang Hari Regency's Original Revenue, and how the Effect of Advertisement Tax Receipts Against the Local Revenue of Batang Hari Regency for the period 2006-2015. Research results show (1) Development of Batang Hari Regency advertisement tax receipts for 2006-2015 The most significant increase in percentage occurred in 2010, which was 46.34%. (2) The development of the original revenue of the Batang Regency in 2006-2015 experienced fluctuations. Realization of the largest Revenue of Regional Original Revenue was achieved in 2014. (3) Admission of Advertising Taxes had a positive effect on the Local Revenue of the Batang Hari Regency. When the Advertising Tax is deemed constant, the Regional Original Income is 146,218,304. Every increase in Advertising Tax revenue will increase Regional Original Income by 8 percent. The determination coefficient (R2) is 0.547. This figure shows that the Regional Original Income is influenced by sebaar Advertising Taxes 54.7 percent. While the remaining 45.3 percent is influenced by other variables not used in this study.
SOLOS E TRATOS CULTURAIS DO SISTEMA DE AGRICULTURA FAMILIAR EM ÁREAS DE BREJO DE ALTITUDE DE AREIA-PB
Authors: Marques Ailson De Lima , Barbosa Ewerton Da Silva , Costa Cássio Ricardo Gonçalves da , Moura Debora Coelho
Published: March 2019

O conhecimento sobre as problemáticas que envolvem o agrário é necessário para a criação e desenvolvimento de alternativas sustentáveis de produção. Diante disso, objetiva-se com essa pesquisa, retratar os fatores que contribuem para o manejo de solos no brejo paraibano, especificamente em comunidades do sistema de economia familiar do município de Areia. Com auxilio entrevistas e questionários pré-estruturados, foram realizadas visitas nas comunidades: Boa Vista, Mundo Novo e Usina Santa Maria. Em cada comunidade foram realizadas as etapas metodológicas com 15 agricultores, totalizando 45. Além disso, houve um mapeamento de uso da terra. O público entrevistado foi composto por mulheres e homens entre 35 a 65 anos de idade, dentre os quais, 40% não completaram o ensino fundamental. Os entrevistados adotam em suas lavouras um nível tecnológico primitivo. Praticamente não há investimento de capital para o manejo, melhoramento e conservação das condições das terras e das lavouras. Em síntese, diante das práticas observadas, tem-se um ambiente com comprometidas condições edáficas, por um manejo de exaustão, além de eminentes processos de erosão decorrentes do plantio em Áreas de Preservação Permanentes (APPs).

Palavras-chave: Meio agrário. Economia familiar. Manejo do solo.
CONHECIMENTO TRADICIONAL DA AVIFAUNA PELOS INDÍGENAS KAYABI, AMAZÔNIA MERIDIONAL, BRASIL
Authors: Dario Fabio Rossano
Published: March 2019

Este estudo teve como objetivo um levantamento do conhecimento que os indígenas Kayabi possuem sobre a avifauna de ocorrência natural na Terra Indígena Kayabi, localizada na Amazônia, entre os estados do Pará e Mato Grosso, Brasil. Para coleta de dados foram realizadas entrevistas com vinte e dois indígenas que citaram 165 espécies de aves e mostraram amplo conhecimento ecológico sobre estas aves, incluindo categorias relacionadas à morfologia, hábitos alimentares, hábitats e vocalização.

Palavras-chave: Aves. Interações ecológicas. Indígenas. Amazônia.
O COMÉRCIO INFORMAL, POLÍTICAS PÚBLICAS E TERRITÓRIO URBANO MOSSOROENSE
Authors: Silva Moacir Vieira da , Araújo Josélia Carvalho de , Gomes Rita de Cássia Da Conceição , Beserra Fábio Ricardo Silva
Published: March 2019

Consiste num estudo de cunho teórico e empírico que objetiva analisar a relação conflituosa entre o Estado e os comerciantes informais – os camelôs – na cidade de Mossoró (Rio Grande do Norte), tomando por base a discussão do conceito de território, enquanto espaço apropriado a partir de relações de poder, e a relação entre as políticas públicas e sua contribuição para a configuração do território. Constata que a atividade comercial informal tem se apropriado dos espaços públicos do centro urbano em tela, contrapondo-se a leis e normas urbanísticas vigentes. Essa apropriação ilegal tem sido a força motriz e impulsora dos conflitos ocorridos entre o Estado e os camelôs na urbe mossoroense. Aponta que não é apenas essa dinâmica que alimenta esse impasse Estado x Camelôs, havendo outras forças e jogos de interesses envolvidos nesse processo - que sobrepuja o cumprimento (ou não) das regras urbanísticas. Resulta de um estudo desenvolvido por meio da leitura de materiais teórico-conceituais, que abordam a discussão de território e de políticas públicas, bem como documentos oficiais normativos, os quais se fizeram o aporte teórico para a análise da realidade do território urbano mossoroense, através de pesquisa de campo em seu núcleo urbano (observação da dinâmica citadina).

Palavras-chave: Comércio Informal. Políticas Públicas. Território Urbano. Mossoró.
MICROCRÉDITO RURAL E AGRICULTURA FAMILIAR NO NORDESTE: UMA ANÁLISE DO PROGRAMA AGROAMIGO NO VALE DO AÇU-RN
Authors: Dantas Geogina Willida , Aquino Joacir Rufino de
Published: March 2019

O objetivo do presente artigo é analisar a evolução e os limites do programa de microcrédito rural Agroamigo na microrregião do Vale do Açu, no estado do Rio Grande do Norte (RN), compreendendo o período de 2006 a 2013. Para tanto, foi realizada uma pesquisa bibliográfica abrangendo as principais publicações acadêmicas sobre o tema, bem como a tabulação de dados estatísticos obtidos por meio da Lei de Acesso Informação e entrevistas com mediadores locais do programa. Em linhas gerais, o trabalho mostra que o Agroamigo se converteu em uma política pública de financiamento importante para os agricultores familiares pobres do Vale do Açu. Ao longo dos seus anos iniciais de existência, o programa realizou mais de 7 mil contratos e investiu na microrregião um volume superior a R$ 15 milhões, sendo uma parcela significativa desses recursos destinada as mulheres rurais. Apesar de seus bons resultados operacionais e dos baixos índices de inadimplência, contatou-se que o microcrédito do Agroamigo tem contribuído pouco para a diversificação das fontes de renda do público atendido, carecendo de uma maior integração com outras ações governamentais para fortalecer as capacidades produtivas das famílias pobres do campo.

Palavras-Chave: Agricultura Familiar. Agroamigo. Microcrédito. PRONAF. Vale do Açu.
Fostering Entrepreneurship among Academia: A Study of Vietnamese Scientist Commercialization
Authors: Van Nguyen Thang , Tuong Nguyen Lan , Ba Nguyen Nham
Published: March 2019

Commercialization of scientists’ inventions greatly contributes to the development of a country, yet the success ratio of this process is very low. Besides, research results on commercialization in developed countries are not readily applicable to Vietnam where the market institution has not been well functioning. This research examines the commercialization of scientists’ inventions in Vietnam (hereafter, scientist commercialization). The objectives are to identify factors that influence Vietnamese scientist commercialization. Drawing on networking, leadership, and motivation theories and data from a sample of scientists working at the Vietnam Academy of Science and Technology, the study shows that access to research funding, networking with businesses, leaders’ experience, and pecuniary and prosocial motivation are positively related to commercialization. The results shed light on the theoretical development of commercialization in developing countries. The research also discusses practical implications for promoting scientist commercialization in Vietnam.
CHRONOPHYSIOLOGY AND CHRONOPATHOLOGY OF CARDIOVASCULAR SYSTEM (Literature Review)
Authors: Zenina O Yu , Makarova I I , Ignatova Yu P , Aksenova A V
Published: March 2019

This review presents modern data on the biorhythms of cardiac activity in healthy individuals and pathological conditions. The article presents the changes in the indices of the cardiovascular system during the day. There are diurnal patterns in changes of heart rate. As in healthy persons and in patients suffering from arterial hypertension bimodality circadian rhythm of blood pressure was revealed. It is emphasized that circadian fluctuations in blood pressure may be associated with the participation of melatonin in the regulation of this indicator of cardiovascular activity. In healthy people circadian fluctuations of intervals duration and the height of ECG waves have been revealed. The people belonging to a certain chronotype influence diurnal variations of indicators of heart rate variability. The results of seasonal fluctuations of indicators of cardiac activity as well as the analysis of the frequency of disease recurrence in different periods of the year, the seasons and during the day are presented. The article describes research data on the effect of natural abiotic stress factors - geomagnetic disturbances on chronostructure biorhythms of the heart. The changes in blood pressure and heart rate in the voltage amplification of the magnetic field of the Earth have been covered. The statistical data proving connection between the heliogeomagnetic activity and an increase in the number cardiovascular accidents have been presented. Using the basic regularities of chronobiology allows us to predict the risk of developing various diseases, primarily cardiovascular diseases, which are the main reason of mortality in the world.
MEDICAL AND BIOLOGICAL EFFICIENCY OF HEALTH TOURISM AMONG YOUTH
Authors: Khodasevich L S , Romanov S M , Polyakova A V , Malyshev A A
Published: March 2019

Literature review is devoted to medical and biological efficiency of health tourism of modern youth, who are characterized by deterioration of health indicators due to the high prevalence of bad habits, lack of knowledge and inexperience in matters of disease prevention, lack of interest in the implementation of health measures and low level of physical activity. The authors describe health tourism as one of the most effective and attractive means of health improvement due to high availability to the youth and fitness of a big part of the territory of the Russian Federation for tourist activities. They consider it as the basis of a healthy lifestyle able to affect on its quality and duration, as well as disease prevention. Healthcare effect of sports and health tourism is greatly enhanced by the fact that they are carried out mainly in the green forest countryside or urban parkland. Physical activity in the conditions of the forest or parkland landscapes provides favorable effect of flora, bioclimate, topography and the picturesque landscape terrain, aimed at disadaptation prevention and improving the general non-specific resistance. Health tourism is similar in its healthcare effect to a sanatorium resort climate landscape therapy, being actually its variation. The health improvement process in both cases is a highly active motor activity, which improves mental performance, the level of the functional state of the cardiovascular, respiratory and muscular systems, forms a harmonious constitution. Physical activity in the forest or parkland offers a man a rare opportunity to approach nature, observe and appreciate its beauty.
TÜRKİYE’DEKİ DİJİTAL PLATFORMLARIN KULLANILABİLİRLİK ÖLÇÜTÜNE GÖRE İNCELENMESİ
Authors: ERASLAN Ergün , NACER Emine Nır , ERDEBİLLİ (B.D.ROUYENDEGH) Babek
Published: March 2019

Teknoloji geliştikçe karmaşık ürün özellikleri de artmakta olduğundan
aktif kullanıcılar için Dijital TV platformlarından yararlanmak zaman
almaktadır. Bu durum da ürün kullanılabilirliğini etkilemektedir.
Kullanıcıların limitli arayüzler vasıtasıyla çeşitli özelliklere ulaşabilmeleri
gerektiğinden Dijital TV platformlarının dizaynındaki kullanılabilirlik önemli
bir konudur. Bu çalışma, kullanılabilirliği en iyi olan Dijital TV platformunu
seçmeyi amaçlamaktadır. Dijital TV platformuna karar vermek için kullanıcı
görüşleri ışığında bir anket oluşturulmuştur. Bu görüşlerin yardımıyla ana
kriterler ve alt kriterler elde edilmiştir. Ana kriterler ve alt kriterler için
ikili karşılaştırmalar yapılmıştır. Bu çalışmanın sonucunda modelin araştırma
yapısı olarak 4 ana kriter ve 11 alt kriter elde edilmiştir. Türkiye’deki 3
farklı dijital TV markası kullanılabilirliklerine göre karşılaştırılmıştır. 14
kullanıcı bu markaları değerlendirmiştir. Çok kriterli karar verme
yöntemlerinden olan AHP (Analytic Hierarchy Process) ve TOPSIS (Technique for Order Preference by Similarity to Ideal Solution) kullanılarak en iyi
alternatif seçilmiştir.
TÜRKİYE’DE STADYUM YAPILARINA ULUSLARARASI STANDARTLAR ÇERÇEVESİNDEN BİR BAKIŞ: KONYA STADYUMLARI SEYİRCİ ERGONOMİSİ ANALİZİ
Authors: ARAT Yavuz , KURUMAK Metin
Published: March 2019

Ergonominin bir alt başlığı
olarak değerlendirilebilecek Mimarlık Ergonomisi, farklı yapı tiplerinde zaman
içerisinde tasarımcı ve mühendislerin ele alması gereken bir çalışma konusu
haline gelmiştir. Ergonomi konusundaki araştırmaların çokluğu ve farklı
disiplinlerdeki arayışlar neticesinde bazı temel prensipler ve standartlar
oluşturulmuştur. Günümüzde inşaat sektörünün çok önemli bir çalışma alanı
olarak tanımlanan spor kompleksi projelerini de bu standartlar dâhilinde
değerlendirmek mümkündür. Çalışma kapsamında incelenen Konya Atatürk (1950) ve
Büyükşehir Stadyumlarının (2014) birincil kullanıcıları olan seyircilerin yapı
formu ile entegrasyonu, ergonomik ve yapısal çerçevede değerlendirilerek süreç
içerisinde değişen ergonomik ihtiyaçların yapı tarafından karşılanma düzeyleri
birçok noktada kıyaslanmıştır. Örneklem olarak seçilen bu iki stadyum,
Türkiye’de yapım dönemleri açısından benzerlik gösteren diğer stadyumlar ile beraber
ele alınmasıyla 20.yy’dan günümüze kadar yapılan stadyumlarda meydana gelen ergonomik
ve yapısal gelişimlere bütünsel bir yaklaşım benimsenmiş olmaktadır. Çalışmanın
amacı dâhilinde yakın zamanda geliştirilen uluslararası stadyum
standartlarının, seyirci mekânları üzerindeki ergonomik ve yapısal etkileri
analiz edilerek, standartların uygulandığı ve uygulanmadığı stadyumlardaki
olumlu ve olumsuz ergonomik durumların tespiti yapılmıştır. Yapılan analizler,
FIFA, UEFA, TFF gibi kuruluşlar tarafından belirlenen yapı yönergeleri ile beraber,
literatür araştırmalarında ortaya çıkan ve alan çalışmalarıyla tespit edilen
bilgileri de içeren karşılaştırmalı analiz tablolarına aktarılmıştır. Çalışma
neticesinde Türkiye'de yapılmış eski stadyumlarla, güncel stadyum projelerinin
söz konusu standartlara ne derecede cevap verebildiğine odaklanılmış ve bu
kapsamda çıkarımlar yapılarak elde edilen bulgular paylaşılmıştır.
Risk Management of Process Moving from Traditional to Agile Software Development
Authors: Mupitra Byan Haqi
Published: March 2019

Agile programming is the popular software project development method in this era. Many company moving from Traditional software development to agile software development. They move to agile to reduce delivery time, user gap and improve quality. When use traditional method, we usually find big gap when we deliver to user. The solution of this problem is agile method. In Agile, we frequently come to users to tell them what we have done to their requirements. So the gap is not too big and we can solve it fast. But moving to agile software development is not easy. There are some risks when we move to new method. The data for this study were drawn from PT. XYZ. This company trying to move from traditional method into agile method. This company wants to move of the development method in all business units. The notion of this paper is to propose the risk management when company moving their method from Traditional into Agile software development based on study PT XYZ.
The Potential Of Blockchain Technology To Change International Mobile Roaming Business Model
Authors: Atmaja Ardian Thresnantia
Published: March 2019

The key objectives of this paper is to propose a design implementation of blockchain based on smart contract which have potential to change international mobile roaming business model by eliminating third-party data clearing house (DCH). The analysis method used comparative analysis between current situation and target architecture of international mobile roaming business that commonly used by TOGAF Architecture Development Method. The purposed design of implementation has validated the business value by using Total Cost of Ownership (TCO) calculation. This paper applies the TOGAF approach in order to address architecture gap to evaluate by the enhancement capability that required from these three fundamental aspect which are Business, Technology and Information. With the blockchain smart contract solution able to eliminate the intermediaries Data Clearing House system, which impacted to the business model of international mobile roaming with no more intermediaries fee for call data record (CDR) processing and open up for online billing and settlement among parties. In conclusion the business value of blockchain implementation in the international mobile roaming has been measured using TCO comparison between current situation and target architecture that impacted cost reduction of operational platform is 19%. With this information and understanding the blockchain technology has significant benefit in the international mobile roaming business.
Blockchain Governance: Perspective An Evaluation from COBIT 5
Authors: Setiadi Ricky , Soetomo M. Amin , Mahawan Bagus
Published: March 2019

Currently blockchain has been recognized and implemented in cryptocurrency sector, but notfor other industry, especially enterprise. Through this research it is expected to help the adoption process of blockchain. The evaluation was conducted on blockchain through testing using COBIT 5 cascaded from Stakeholder Question to IT Process. 35% of organization goal is applicable with selected stakeholder question, while 65% is applicable with IT related goal. The results of the analysis stated that finding of this study was more applicable for enterprise organizations such as fintech company with some parameters need to be added as the future work due to the enterprise organization had a lot of business and governance processes that were already running. Meanwhile the start-up organization can be audited as well based on this process.
Energy Consumption Analysis to Detect Process Failure in Rubber Compound Mixing Process
Authors: Triyanto Agus
Published: March 2019

There are many ways to detect the abnormality of rubber mixing process regardless of the availability of indicator system of the abnormality. One way is to detect the problem after the result of rubber production tested by laboratory teams. Abnormality will be late to be anticipated because the result of the test will appear after 8 to 10 batch afterward. The abnormality in the mixing process will be detected if the results of the testing compound are out of the specification. The energy consumption will be measured for every batch by using the internal current sensor in the AC motor main drive. By reading the figure of measurement, energy consumption character will be identified and the specification standard of energy consumption can be defined. The process will follow the specification standard of energy consumption and abnormality condition will be corrected immediately.
Analisis Faktor-Faktor Yang Mempengaruhi Mahasiswa Memilih Program Studi Pendidikan Olahraga Universitas Bina Darma
Authors: Wanda Erwanda , Satria M Haris
Published: March 2019

Penelitian ini bertujuan untuk mengetahui faktor yang mempengaruhi mahasiswa memilih program studi Pendidikan Olahraga Universitas Bina Darma.Penelitian ini merupakan penelitian deskriptif kuantitatif. Subjek penelitian ini adalah mahasiswa program studi Pendidikan Olahraga Universitas Bina Darma angkatan tahun 2015 sampai dengan 2017 sebanyak 79 responden. Variabel penelitian adalah faktor internal yaitu: minat, motivasi, cita-cita dan faktor eksternal yaitu: keluarga, lingkungan, teman sebaya. Teknik pengumpulan data menggunakan angket sejumlah 69 item pernyataan. Berdasarkan data hasil angket didapatkan mahasiswa yang memilih faktor minat(62,02%), faktor motivasi (15,19%), faktor cita-cita (12,66%), faktor keluarga (6,33%), faktor lingkungan (1,26%), dan faktor teman sebaya (2,53%), sehingga jika ditotal faktor yang paling dominan dipilih adalah faktor minat.