bluuebunny/crossref_metadata_2025 huggingface dataset:
Lower energy intake associated with higher risk of cardiovascular mortality in chronic kidney disease patients on a low-protein diets
Authors: Liu Yao , Deng Fei , Zhou Ping , Peng Cong , Xie ChunPeng , Gao Wuyu , Yang Qianyu , Wu Tingyu , Xiao Xiang
Published: September 2023

Objective
An increasing number of studies shown that inadequate energy intake causes an increase in adverse incidents in chronic kidney disease (CKD) patients on low-protein diets (LPD). The study aimed to investigate the relationship between energy intake and cardiovascular mortality in CKD patients on a LPD.
Methods
This was a cross-sectional study, a total of 4264 CKD patients were enrolled from the NHANES database enrolled from 2009 to 2018. Restricted cubic spline plots and Cox regression analysis were used to analyze the association between energy intake and cardiovascular mortality in CKD patients on a LPD. Additionally, a nomogram was constructed to estimate cardiovascular survival in CKD patients on a LPD.
Results
Among CKD patients on a LPD in the United States, 90.05% had an energy intake of less than 25kcal/kg/day, compared to 36.94% in CKD patients on a non-LPD. Energy intake and cardiovascular mortality showed a linear relationship in CKD patients on a LPD, while a 'U-shaped' relationship was observed in CKD patients on a non-LPD. Multifactorial Cox regression models revealed that for Per-standard deviation (SD) decrement in energy intake, the risk of cardiovascular mortality increased by 41% (HR: 1.41, 95% CI: 1.12, 1.77; P = 0.004) in CKD patients on a LPD. The concordance index of the nomogram was 0.79 (95% CI, 0.75-0.83).
Conclusion
CKD patients, especially those on a LPD, have significantly inadequate energy intake. Lower energy intake is associated with higher cardiovascular mortality in CKD patients on a LPD.
Anti-tumor effectiveness of a novel bispecific antibody that blocks both PD-L1 and LAG-3
Authors: Zhang Chenxing , Liu Jiaxin , Zhu Shidong , Zhang Youfeng , Wang Linlin , Gu Tiejun , Meng Xiangyu , Zhang Daguang , Wu Yongge
Published: September 2023

Over the past few years, significant progress with promising outcomes has been made in the use of antibodies against programmed cell death protein 1 (PD-1) and its ligand (PD-L1) for immunotherapy. However, several issues still limit their effectiveness for anti-cancer therapy. Therefore, we designed a bispecific antibody (BsAb) against PD-L1 and T cell immune checkpoint lymphocyte activation gene-3 (LAG-3), in an attempt to block both targets to further improve immune efficacy against solid tumors. A bispecific T cell engager structure was used to connect the variable regions of the PD-L1 and LAG-3 antibodies in series. We further constructed a recombinant plasmid and used a prokaryotic expression system to prepare the antibody. The affinity and blocking activities of the antibody was verified using an enzyme-linked immunosorbent assay, and the affinity of the antibody was further verified at the cellular level using flow cytometry and fluorescence microscopy. Furthermore, we preliminarily evaluated its anti-tumor effects in mice. Collectively, the antibody prepared using the prokaryotic expression system had preferable tumor cell-targeting ability and blocked the interaction of PD-1 and LAG-3 with their ligands. Further, the results of the animal experiments demonstrated that the BsAb exerted a certain anti-tumor effect. Overall, our study suggests that this strategy has therapeutic potential for liver hepatocellular carcinoma and breast invasive carcinoma.
Centrosymmetric, non-symmorpic, non-magnetic, spin-orbit coupled layers without Dirac cones
Authors: Damljanovic Vladimir
Published: September 2023

While considering appearance of Dirac cones in spin-orbit coupled two-dimensional materials, S. M. Young and C. L. Kane (Physical Review Letters 115 (2015) 126803) have found that, in the absence of other symmetries, spatial-, time-reversal and vertical glide plane (or horizontal screw rotation) symmetry give four-fold degenerate Dirac point at the time-reversal invariant momentum along the fractional translation. Here we show in which cases these additional symmetries lead to Dirac line instead of Dirac cone in the band structure. We found three centrosymmetric, non-symmorphic layer double groups with line-like degeneracies instead of nodal points. We show that besides these Dirac lines, no other band contacts occur, including the accidental ones. Our results are illustrated with a tight binding example arising from s-orbitals on two atoms in the primitive cell. Finally, we discussed ways towards realistic materials where such features in the electronic dispersion are expected to appear.
Causal effects of gut microbiota on ARDS: a two-sample Mendelian randomization study
Authors: Yang Dongliang , Guo Hongyan , Xia Rui , Wen Chao , Kang Jian , Liu Ying , Yang Suosuo , Ren Yanbo , Wang Hui , Li Jianhua , Li Yuling
Published: September 2023

Background A growing number of studies showed that altered gut microbiota is associated with the pathogenesis of ARDS. However, the potential causal relationship remained unclear. Herein, we adopted a two-sample Mendelian randomization (MR) study to investigate the causal relationship between gut microbiota and ARDS.
Methods We used publicly available genome-wide association study (GWAS) summary data to perform MR analysis. Gut microbiota GWAS were obtained from the MiBioGen study and summary-level GWAS dataset for ARDS were obtained from the IEU OpenGWAS Project. MR-Egger, weighted median, inverse variance weighted (IVW), simple mode and weighted mode methods were used to investigate the causal relationship and IVW method was considered as the primary approach. Additionally, a set of sensitivity analyses, including the MR-Egger intercept test, Cochran’s Q test, and leave-one-out test, were carried out to evaluate the robustness of our findings.
Results Our study identified eight microbial taxa that were causally associated with ARDS risk.
The increased abundance of Phylum Actinobacteria(odds ratio [OR]: 0.22, 95% confidence interval [CI]:0.07-0.68, P=0.008), genus Intestinibacter(OR: 0.40, 95% CI: 0.16–0.98, P=0.045) and genus Eubacterium ruminantium group (OR: 0.52, 95% CI: 0.27–1.00, P=0.049) were negatively associated with the risk of ARDS, while the abundance of genus Victivallis (OR: 2.55, 95% CI: 1.22–5.35, P=0.013), class Erysipelotrichia(OR:3.69 , 95% CI: 1.06-12.82, P=0.040), order Erysipelotrichales(OR:3.69, 95%CI:1.06-12.82,P=0.040), family Erysipelotrichaceae(OR: 3.69, 95% CI: 1.06-12.82, P=0.040), and genus Ruminococcaceae UCG014 (OR:2.92, 95% CI: 1.02-8.34, P=0.044) were positively correlated with the risk of ARDS. Sensitivity analysis revealed no evidence of heterogeneity and pleiotropy.
Conclusions This study is the first to provide suggestive evidence for a causal relationship between certain gut microbiota and the risk of ARDS, providing valuable insights into the pathogenesis of microbiota-mediated ARDS and potential targets for ARDS treatment.
Associations of Various Internet Device Use and Activities with Depression in Chinese Adolescents: Gender and Geographical Differences
Authors: Wang Sasa , Gao Chenzhuo , Yang Xueyan
Published: September 2023

Purpose
Chinese adolescents are increasingly using multiple devices to engage in various Internet activities. This study sought to examine the associations of diverse Internet device use and distinct activities with depression among Chinese adolescents across genders and geographical locations.
Methods
We used data from China Family Panel Studies (CFPS), a national survey conducted in 2020.
Results
Moderate use of different Internet devices posed no risk of depression and could even alleviate it. Posting WeChat Moments frequently was positively linked to depression. Regarding gender differences, mobile device usage time and frequency of watching short videos were associated with higher levels of depression in girls, while opposite associations were observed in boys. Regarding geographical differences, moderate use of mobile devices (1–3 hours per day) and desktop devices (< 1 hour per day), including watching short videos and posting low-frequency on WeChat Moments, were associated with lower risk of depression among rural adolescents. Long-time desktop device use (> 1 hour per day), playing online games, daily online learning, and posting high-frequency on WeChat Moments could increase their risk of depression. In contrast, desktop device use and moderate mobile device use (1–3 hours per day), mainly represented by watching short videos and posting low-frequency on WeChat Moments, were related to depression among adolescents in provincial capitals, prefecture-level cities, or counties. Daily online learning, playing games, and posting WeChat Moments frequently could relieve their depression.
Conclusion
The risk factors for depression related to Internet device use and activity varied between adolescents across genders and geographical locations.
Regional-based approach during anatomy coursework results in better academic performance than systemic-based approach
Authors: Costa Thalles Guilarducci , Campos Mario Hebling , Barros Ana Claudia , Andrade Marilia , Vancini Rodrigo Luiz , Viana Ricardo Borges , Lira Claudio Andre Barbosa
Published: September 2023

Background
The study of human anatomy is of major importance in health sciences, including sports and exercise undergraduate programs. There are some approaches to human anatomy teaching, such as systems-based gross anatomy course and regional-based gross human anatomy course, both ways are highly recommended, but, to the best of our knowledge, no study compared the difference between them on academic performance and attendance to class.
Objective
To evaluate the academic performance of undergraduate students enrolled in human anatomy courses taught by systems-based or regional-based approaches. Methods: The final grade and class attendance of 141 Sport and Exercise Science Undergraduate Students who attended the functional human anatomy of the locomotor apparatus coursework were analyzed. Of the participants enrolled, 70 students were enrolled in the systems-based gross human anatomy approach (SAG) and 71 students were enrolled in the regional-based gross human anatomy approach (SEG). Results: Students enrolled in SEG (7.3 [2.0]) had better academic performance (U = 1804.5, p = 0.005; r = 0.274 [0.09–0.44]) than SAG (6.6 [1.6]). Class attendance was higher in SEG (60 [8]) compared to SAG (60 [7]) (U = 1919.5, p = 0.015; r = 0.228 [0.040–0.399]). Conclusion: SEG leads to better academic performance in the anatomy gross course and higher attendance compared to SAG.
Quantum Audio LSB Steganography with Entanglement-assisted Modulation
Authors: Hao Chaolong , Yang Xukui , Ma Quangong , Qu Dan , Wang Ran , Zhang Tao
Published: September 2023

This paper introduces two novel quantum audio steganography methods that incorporate the logical properties of entangled qubits into the least significant qubit steganography (LSQb) approach. The first method, called entanglement-assisted probability adjustment LSB (EP-LSQb), optimizes the superposition probability of the lowest qubits before embedding the information. This addresses the ‘value-pairing’ problem and improves anti-statistical analysis performance and embedding efficiency. The second method, called quantum phase direct embedding LSB (PD-LSQb), extends traditional LSB steganography by directly embedding the secret speech into the least significant qubit. Quantum circuits are constructed for both methods to demonstrate their feasibility. Theoretical analysis and simulation experiments show that these methods exhibit good imperceptibility (\({\text{PSNR}}>50\)) and embedding efficiency. Particularly, EP-LSQb method enhances the theoretical limit of embedding efficiency when compared to its corresponding classical counterparts. Additionally, due to the inclusion of entangled qubit particles, our methods offer competitive content security and noise robustness, distinguishing them from classical LSB or general LSQb methods and highlighting the unique advantages of quantum approaches.
Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1
Authors: Engelhardt Maike , Hintze Stefan , Wendegatz Eva-Carina , Lettow Julia , Schüller Hans-Joachim
Published: September 2023

Binding of general transcription factors TFIID and TFIIA to basal promoters is rate-limiting for transcriptional initiation of eukaryotic protein-coding genes. Consequently, activator proteins interacting with subunits of TFIID and/or TFIIA can drastically increase the rate of initiation events. Yeast transcriptional activator Ino2 interacts with several Taf subunits of TFIID, among them the multifunctional Taf1 protein. In contrast to mammalian Taf1, yeast Taf1 lacks bromodomains which are instead encoded by separate proteins Bdf1 and Bdf2. In this work we show that Bdf1 not only binds to acetylated histone H4 but can also be recruited by Ino2 and unrelated activators such as Gal4, Rap1, Leu3 and Flo8. An activator binding domain was mapped in the N-terminus of Bdf1. Subunits Toa1 and Toa2 of yeast TFIIA directly contact sequences of basal promoters and TFIID subunit TBP but may also mediate the influence of activators. Indeed, Ino2 efficiently binds to two separate structural domains of Toa1, specifically with its N-terminal four-helix bundle structure required for dimerization with Toa2 and its C-terminal β-barrel domain contacting TBP and sequences of the TATA element. These findings complete the functional analysis of yeast general transcription factors Bdf1 and Toa1 and identify them as targets of activator proteins.
The Impact of Hemp Seed Oil on Drug-Drug Interactions: A Comprehensive Review of Potential Mechanisms and Clinical Implications
Authors: Solaimanian Shahabaddin , Rahmani Bita , Shiri-Shahsavar Mohammad Reza
Published: September 2023

Hemp seed oil (HSO), esteemed for its potential health benefits and therapeutic attributes, has garnered substantial attention in recent years. However, the escalating consumption of HSO has engendered apprehensions regarding its potential interactions with pharmaceutical medications, posing the risk of adverse effects or altered drug efficacy. This comprehensive review diligently explores and elucidates the underlying mechanisms through which HSO may interact with a spectrum of drugs, accompanied by an extensive assessment of the clinical ramifications of these interactions. By assiduously unraveling these intricate dynamics, this review equips healthcare professionals and consumers with the knowledge to make judicious decisions concerning the concurrent use of HSO and prescription medications. Moreover, this comprehensive review endeavors to identify and address research gaps, charting a route for future investigations in this critical domain. This review sheds light on HSO's impact on drug-drug interactions (DDIs), delivering invaluable insights for healthcare professionals, researchers, and consumers and fostering the responsible and informed incorporation of this natural product across diverse therapeutic contexts.
Research trends on interventional studies for Mild Cognitive Impairment (MCI): A bibliometric analysis using CiteSpace
Authors: Karim Mani Abdul , Venkatachalam Jonnadula
Published: September 2023

Background
Mild Cognitive Impairment (MCI) is a transitional stage between normal aging and the onset of dementia. The early detection of MCI is essential to avoid certain irreversible brain damage at the end of life. While there have been a variety of preventive interventions used in the past three decades, need to know the current trends is necessary for developing updated preventive modules for MCI.
Objectives
This bibliometric study examines the current trends in interventional research for treating MCI.
Methods
Published records were obtained from the Web of Science Core Collection (WoSCC) for the period of 1989–2023. CiteSpace 6.2.R4 (64-bit) advanced version software was utilized for mapping and bibliometric analysis of this study. Overall, 400 records were retrieved and analyzed using document co-citation analysis (DCA), author co-citation analysis (ACA), institutional, country based, and keyword analysis.
Results
It was found that the publication records were steadily increased in the recent five years (2018–2022) and shows that more than half of the interventional studies (234) were conducted on the recent times. Although United States (US) published highest number of publications (115), Canada secured top position based on burst (3.89) in country wise analysis. In ACA, Petersen RC_2003 secured top position based on citation counts (237), Rapp S_2006 on Burst strength (10.69), Ball K_2006 on Centrality (0.19) and Sigma value (2.00). Through the DCA analysis, clusters such as computerized cognitive training, virtual reality, rhythm training, and dance intervention, were considered to be the indicators of emerging trends.
Matkailunkestävä Suomi? Vastuullinen suunnittelu kulttuuri- ja luontoympäristöissä
Authors: Veijola Soile
Published: September 2023

Tourism planning for the future: Responsible planning in culture–nature environments in Finland Tourism must be planned and developed differently from what is customary today, as growth in rigid economic terms is still prioritised over the cultural and socioecological sustainability of lived-in cultural and natural environments. The global ecological crisis can no longer be ignored by tourism developers and investors – or by tourists. The seventeen authors of this book are from a variety of disciplines and fields of expertise. Through research-driven and profession based knowledge on different aspects of tourism planning in Finland and elsewhere, they offer transformative perspectives and practical applications for responsible tourism planners, investors and political decision-makers to utilise. Through the book’s overarching themes – learnings from the history of tourism planning, wellbeing, participation, building and architecture, people and infrastructure – it addresses a general audience, professional communities, and academic communities. The book’s urgent quest is to prevent tourism from remaining one of the causes for the greatest problem of all time, the worsening baseline of living conditions on Earth.
Pfaffian invariant identifies magnetic obstructed atomic insulators
Authors: Araya Day Isidora , Varentcova Anastasiia , Varjas Daniel , Akhmerov Anton R.
Published: September 2023

We derive a \mathbb{Z}_4ℤ4
topological invariant that extends beyond symmetry eigenvalues and
Wilson loops and classifies two-dimensional insulators with a
C_4 \mathcal{T}C4𝒯
symmetry. To formulate this invariant, we consider an irreducible
Brillouin zone and constrain the spectrum of the open Wilson lines that
compose its boundary. We fix the gauge ambiguity of the Wilson lines by
using the Pfaffian at high symmetry momenta. As a result, we distinguish
the four C_4 \mathcal{T}C4𝒯-protected
atomic insulators, each of which is adiabatically connected to a
different atomic limit. We establish the correspondence between the
invariant and the obstructed phases by constructing both the atomic
limit Hamiltonians and a C_4 \mathcal{T}C4𝒯-symmetric
model that interpolates between them. The phase diagram shows that
C_4 \mathcal{T}C4𝒯
insulators allow \pm 1±1
and 22
changes of the invariant, where the latter is overlooked by symmetry
indicators.
ESTIMATION AND COMPARISON OF PLATELET COUNT: AUTOMATED ANALYZERVS MANUAL PERIPHERAL SMEAR METHOD
Authors:   Demonstrator, Department of Pathology, GMC Doda., Rana Himanshu , Sheikh Mahvesh ,   Demonstrator, Department of Pathology, GMC Doda.
Published: September 2023

Accurately assessing platelet counts holds paramount importance in the realm of diagnostics and treatment. The adoption of automated methods within the diagnostic landscape is steadily growing, attributed to their multifaceted benefits. Nonetheless, automated analyzers sometimes yield erroneous results, particularly in scenarios involving particles of comparable sizes or instances of light scattering. These encompass fragmented red blood cells (RBCs), microcytic RBCs, and the presence of oversized platelets or platelet clusters. In response, the manual estimation of platelet counts using Leishmans stain validation gains significance. Method: this study encompassed the collection of blood samples from a diverse pool of 100 patients, including both inpatients and outpatients, spanning the period from 1st February 2023 to 31st July 2023. These samples, procured from GMC Doda and its affiliated hospital, were collected in ethylenediaminetetraacetic acid (EDTA) tubes. The manual platelet count was done, followed by a comprehensive comparative analysis with the counts obtained through automated platelet analysis. Results: the outcomes unveiled a nuanced trend, with manual slide-derived results slightly surpassing those generated by automated analyzers. Conclusion: This study concluded a discernible correlation between automated and manual methodologies for platelet count assessment. Nevertheless, in instances marked by exceedingly high or low platelet counts, the manual method holds its ground, ensuring precision by circumventing concerns like platelet clumping or uneven distribution.
LEGAL PROTECTION OF JOINT SECTION MANAGER OF RAJAWALI TOWER EDELWEISS CONDOMINIUM FLATS (PPRSH-KRME)
Authors:   Office of Notary & PPAT Agung Hartanto, SH, M.Kn, Purbalingga., Thamrin Suryani
Published: September 2023

There is a case in the decision of the Central Jakarta District Court Number 546/Pdt.G/2014/PN-Jkt.Pst, then the level of appeal is with the decision of the Jakarta High Court Number 514/PDT/2016/PT.DKI, then the level of cassation is with the decision of the Supreme Court Number 2711K/Pdt/2017, then the final attempt at the Review level with the Supreme Court decision Number 299PK/Pdt/2019 regarding the hallway which is a joint part of the flats in the Rajawali Menara Edelweiss condominium residence is certified by PT. Jaya Nur Sukses as the developer on behalf of PT. Jaya Nur Success. Residents Association of Rajawali Menara Edelweiss Residential Flats (PPRSH-KRME) as the manager of the flat filed a lawsuit against PT. Jaya Nur Success, because he was evicted from the location which has been occupied by PPRSH-KRME as the management office. Here there is negligence and intention of PT. Jaya Nur Sukses as the developer in the certificate has elements of unlawful acts. But PT. Jaya Nur Sukses as the defendant still insists on continuing the case to the last stage in a civil case, namely review. The method used is the Legislative Approach and the Case Approach. The research results obtained are that the part that is certified is included in the joint part of the flat, which is jointly owned and is under the management of PPRSH-KRME. Evidenced by the master plan and descriptions as well as witnesses who know that the place was previously used as a management office before it was used for public facilities.
Adaptação Transcultural e Avaliação da Validade e Confiabilidade da Male Body Attitudes Scale em Homens Brasileiros
Authors: Almeida Maurício , Resende Thainá Richelli Oliveira , Campos Priscila Figueiredo , De Carvalho Pedro Henrique Berbert
Published: September 2023

O presente estudo realizou a tradução e avaliação da validade e confiabilidade da Male Body Attitudes Scale (MBAS) para homens brasileiros. Foram realizadas as etapas de tradução, síntese de tradução, retrotradução, comitê de especialistas e pré-teste. Logo após, a versão brasileira da MBAS foi aplicada em uma amostra de 454 homens universitários, com idade entre 18 a 35 anos. Foi avaliada a estrutura fatorial da escala por meio de análise fatorial confirmatória (validade fatorial), bem como a validade convergente, por meio de associação entre os escores da MBAS e sintomas de dismorfia muscular, insatisfação corporal, busca pela muscularidade e comprometimento psicológico ao exercício físico. A confiabilidade foi estimada pela análise de consistência interna e pela técnica teste-reteste, com um intervalo de duas semanas. Os resultados indicaram que a versão brasileira da MBAS replica a estrutura fatorial original da escala composta por três fatores (Musculatura, Gordura Corporal e Altura) e 24 itens, apresentando bons índices de ajustamento (χ²/gl = 3,523; CFI = 0,95; TLI = 0,95; SRMR = 0,06; e RMSEA = 0,06 [IC 95%: 0,06, 0,08; p = 0,019]). A MBAS apresentou ainda adequada validade convergente. Foi observada boa consistência interna (coeficiente alfa de Cronbach de 0,87) e estabilidade teste-reteste (coeficiente de correlação intraclasse igual a 0,89; p < 0,001), atestando a confiabilidade da versão brasileira da MBAS. Conclui-se que a MBAS foi traduzida e adaptada para população brasileira e apresentou bons indicadores psicométricos de validade e confiabilidade em uma amostra de homens universitários.
Estudo de tendência do consumo de psicofármacos em município de Minas Gerais sob risco geológico
Authors: Carneiro Gabriella Cristine Almeida , Gualberto Flávia , Valentin Aline , Filho Antônio Ignácio de Loyola Filho , Reis Edna , Ramalho de Oliveira Djenane , Nascimento Mariana
Published: September 2023

O objetivo deste trabalho foi analisar a tendência do consumo de psicofármacos por usuários do Sistema Único de Saúde em município sob risco geológico (Congonhas, Minas Gerais). Trata-se de um estudo farmacoepidemiológico descritivo, do tipo estudo quantitativo de consumo, referente à utilização de psicofármacos. Uma análise descritiva completa dos psicofármacos dispensados foi realizada para os períodos globais antes (2018) e após (2019) o rompimento da barragem de Brumadinho, de acordo com os princípios ativos e grandes classes terapêuticas (antidepressivos e benzodiazepínicos). As quantidades dispensadas nos dois períodos propostos foram ainda descritas de acordo com o sexo do paciente e com o risco de inundação da região da unidade de atenção primária à saúde do participante em caso de rompimento de barragem. Os resultados mostraram um aumento no total e na média de unidades dispensadas por dia útil com estoque disponível de antidepressivos (aumento de 0,6% e 5,2%, respectivamente). Por outro lado, no que se refere aos benzodiazepínicos, identificou-se redução no total e na média de unidades dispensadas por dia útil com estoque disponível (redução de 7,2% e 3,3%, respectivamente). O estudo possibilitou conhecer a tendência de consumo desses medicamentos visando a uma melhor reorganização da assistência farmacêutica do município de Congonhas ante os novos desafios impostos pela realidade geológica.
Dynamic response of high and thin rock slope under blasting vibration: a case study
Authors: Sun Pengchang , Li Ruize
Published: September 2023

The topography of a thin double-sided rock slope differs greatly from that of a regularly studied single-sided rock slope, which leads to difficulties in investigating the dynamic response of the thin double-sided rock slope. Through a case study, this paper provides a specific prospect on the dynamic response of the high and thin rock slope under blasting vibration. The high and thin rock slope belonging to Chiwan Mountain was selected as the typical case slope. Field monitoring programs for blasting vibration on the case slope were carried out using vibration monitoring systems. The amplitude, frequency, and energy characteristics of the recorded blasting vibration were then concretely identified and examined. The monitoring results were further used to validate the dynamic finite element model developed to explore the effects of blasting vibration frequency and amplitude on the dynamic response of the slope. The dynamic finite element model of the case slope subjected to blasting vibration was established using the software LS-DYNA. According to the monitoring and numerical results, the dynamic response mechanism of the high and thin rock slope under blasting vibration was discussed. The results indicate that the elevation amplification effect of blasting vibration exists on the southern slope from a certain elevation, and the dominant frequencies generally decay with the distance from the blasting source but remain largely the same within a specific elevation range. The blasting vibration frequencies have considerable influence on both the values and distributions of peak particle velocities on the slope while the blasting vibration amplitudes have an impact only on the values of peak particle velocities. The dynamic response of the case slope under blasting vibration results from the joint effects of blasting seismic wave propagation and structural resonance. The research findings may pave an effective way to clearly understand the dynamic response of similar high and thin rock slopes under blasting vibration.
Application of advanced machine learning algorithms and geospatial techniques for groundwater potential zone mapping in Gambela Plain, Ethiopia
Authors: Seifu Tesema Kebede , Eshetu Kidist Demessie , Woldesenbet Tekalegn Ayele , Alemayehu Taye , Ayenew Tenalem
Published: September 2023

Groundwater availability is one of the key anxieties in most semi-arid regions of Ethiopia. The purpose of this study was to investigate the groundwater potential zone map of the alluvial plain of Gambela. The study applied analytic hierarchy process (AHP) models with four different machine learning algorithms: random forest classifier (RFC), gradient boosting classifier (GBC), decision tree classifier (DTC), and K-neighbor classifier (KNC). The features that are used as predictors include geology, geomorphology, slope, soil, lineament density, drainage density, land use and land cover (LULC), normalized difference vegetation index (NDVI), topographic wetness index (TWI), topographic roughness index (TRI), and rainfall. The final output of the groundwater potential zone was classified as low, moderate, high, and very high potential zones. The authentication through receiver operating curve (ROC) shows 78.2, 93.4, 92.5, 72.4, and 87.7% values of area under the curve (AUC) for AHP, RFC, GBC, DTC, and KNC, respectively. The results show that RFC and GBC are the best groundwater potential zone (GWPZ) map estimator. The study also shows that rainfall and geomorphology are the primary factors influencing the GWPZ. The outcome might promote improved management alternatives in other areas of the country with a comparable climate.
Using the multiple linear regression based on the relative importance metric and data visualization models for assessing the ability of drought indices
Authors: Zarei Abdol Rassoul , Mahmoudi Mohammad Reza , Ghasemi Aryan Yaser
Published: September 2023

In this study, the power of 12 of the most widely used meteorological drought indices was compared. For this purpose, the datasets of 12 stations (from 1967 to 2021) with different climatic conditions in Iran were used. For statistical analysis, multiple linear regression based on the relative importance metric introduced by the Lindeman, Merenda, Gold (MLR-LMG) and data visualization (DV) models were used. In the temporal assessment, the relative importance metrics (RIM) between the drought severity based on the different drought indices and the annual yield of rain-fed winter wheat (AYW) based on the fitted MLR-LMG model was investigated at the annual timescale in the chosen stations. In the spatial evaluation, the RIM between the drought severity based on the different drought indices and the AYW were investigated each year (1967, … , 2021). The results showed that in temporal assessment, the modified standardized precipitation evapotranspiration index (MSPEI) was the most suitable (58.33% of selected stations). Also, in spatial evaluation, the MSPEI and Z-score were the most efficient drought indices (65.45% and 27.27% of the years, respectively). The validation results of the fitted MLR-LMG models showed that the models were trustworthy in all stations and all years.
ENSINO DE GÊNEROS ACADÊMICOS
Authors: Eliete Correia dos Santos  , Gomes Lídia Santos do Nascimento
Published: September 2023

O objetivo geral desta pesquisa é analisar a aplicabilidade de uma proposta teórico-metodológica de ensino de gêneros acadêmicos à luz dos preceitos de Bakhtin e do Círculo quanto às Ciências Humanas na universidade e na vida no curso de graduação em Arquivologia, no período remoto emergencial causado pela pandemia da Covid-19. Entre os modelos de pesquisa qualitativa, direcionada ao ensino, optamos pela pesquisa-ação para gerar e selecionar os dados e para construção da proposta teórico-metodológica de ensino de gêneros acadêmicos e pesquisa interpretativista para análise dos dados. Os participantes da pesquisa foram os alunos do curso de Arquivologia. Utilizamos ferramentas como o Google Meet, Classroom, Google Forms, WhatsApp e o Excel. A partir daí, analisamos a aplicabilidade das cinco diretrizes de ensino criadas por Santos (2013) em situação de ensino remoto. Os dados comprovam que a interação verbal e o diálogo foram fundamentais para o desenvolvimento do processo pedagógico. A diversidade de propostas que buscou fazer do aluno protagonista resultou em um maior empenho nas atividades, tanto nas aulas síncronas como nas assíncronas. Conclui-se que o grande impacto desta investigação foi analisar o ensino de gêneros em um cenário virtual, considerando os pontos positivos, desafios e os limites das metodologias ativas empregadas pelo professor para conseguir um processo de ensino-aprendizagem menos chocante perante o aluno e mais próximo dele, resultando em uma considerável interação verbal no uso de ferramentas digitais.
Tooth fairies and little mice: cultural difference and wordplay in the translations of Mummy Never Told Me and other picturebooks by Babette Cole
Authors: Quesada Cristina
Published: September 2023

: Foreign children’s literature has had a significant presence in Spain for some decades. Many picturebooks on the Spanish market today are written and illustrated by authors and artists from different countries. This includes many of the picturebooks by Babette Cole, which have been published in translation since the early 1990s. When observing the translations of Cole’s picturebooks, it is possible to find different methods used by translators in order to adapt the stories to the culture of the target country, which sometimes can lead to incoherence between word and image. In this article I will present an analysis of the Spanish translations of Babette Cole’s picturebooks, while having a look at some translations publishedin other languages such as French or Italian. This analysis will be developed by marking the techniques and challenges translators face regarding cultural differences and wordplay.
From inflation to translation: a study of Syrian banknotes
Authors: Khatoon Abeer
Published: September 2023

This study examines Syrian banknotes as translations of the nation. Through a contextualised visual analysis, it showcases the interrelatedness of political reality and money design, focusing on the issue of 500-, 1000-, 2000-and 5000-pound notes in the context of the Syrian war (2011-present). With the aim of demonstrating the potency of abstract icons to address, reinforce and/or deflate questions of power and representation, the study offers insights into the (re)fashioning of national identity at a time of political crisis. Authorised by the government, money iconography reflects the effects of the Syrian war and contributes to the self-fashioning of the Syrian state at large.
Financial matters affecting Mozambican professional translators and interpreters: a survey
Authors: Magaia Armando
Published: September 2023

This study investigates the financial challenges affecting translators and interpreters in Mozambique. Specifically, the study seeks to describe the Mozambican translators’ and interpreters’ business context. By means of a survey questionnaire, qualitative and quantitative data was collected from 42 participants. Data analysis led to the conclusion that Mozambican translators and interpreters are relatively young adults, who mostly offer freelance services on a part-time basis while holding a full-time job elsewhere, and that few of them have a pension scheme. It also identifies two distinct levels of income amongst these professionals. These findings highlight the need to equip translation and interpreting students with skills beyond their field of expertise to enhance graduate employability.
Taboo transactions: an initial diachronic approach to translation and sex work
Authors: Duffy Emily
Published: September 2023

Translation is an ever-evolving form of transmission that carries with it ideas, hopes, politics, poetics, and desires. Building upon Gayatri Chakravorty Spivak’s assertion that “translation is the most intimate form of reading,” the present paper explorestranslation as a form of labor that can be described as intimate through metaphor and history. This paper offers a diachronic perspective on translation and erotic labor through the lens of metaphor, theory and translation history, andproposes that the marginal nature of both sex work and translation reflects a cultural aversion to alterity or otherness. Situated within these overlaps, this paper will trace 1) erotic dimensions of translation depicted through theory and metaphor; 2) a discussion on the figure of the yoginī from Hindu Tantric religion as well as the colonial construct of “sleeping dictionaries” as translator/ consort figures; and 3) examples from the contemporary intersections of translation, global commerce, and sex work.
Illustrating Alice in Wonderland in the New Millennium: New Meanings for an Evergreen Children’s Classic
Authors: Ciancitto Salvatore
Published: September 2023

The link between words and pictures is an internal feature of children’s literature. This bundle of meanings can be a real challenge for the translator, who has to work both on words and on the pictures and their relation to the words. All this is particularly important when a text has been originated with pictures as an integral part of it, with continuous inter-referential connections between words and pictures and whose illustrations were decided by the author of the book, as it is the case for “Alice inWonderland” by Lewis Carroll, a text which had been re-translated and re-edited several times, by providing it with new sets of images. Thus, the aim of this paper is to show the visual representations of Alice in the last decade, comparing the original drawings by Tenniel with the pictures used in Italian publications, in the attempt to unveil new ways in which Carroll’s character and her world have moved from a Victorian fantasy in order to gain eventually new cultural meanings
Translating Art and Artworks in Picturebooks: Interpictoriality and Experiential Meaning-Making for Young Readers
Authors: Wang Yaxi
Published: September 2023

As a popular platform for young readers, picturebookshave been used to invoke various artistic forms, enabling the development of artistic knowledge and visual literacy in children. This study examines theproperties of three interpictorialpicturebooks and discusses how theymediate art for children with differing levels of aesthetic awareness, framed by a discussion of interpictoriality more generally.
Repetition and Addition as Coherent Devices in Audio Description of Comics: A Case Study of X: Big Bad English
Authors: Liu Chunwei
Published: September 2023

: Audio Description (AD) translation is an important translational practice that promotes the accessibility of visual texts for the visually impaired audience. Although AD translation has been developed to be a regular practice in performing arts and entertainment, its potential has not been fully explored for visual-verbal sequential arts such as comics to meet the demand of the audience. To fill in such a gap, this article performs a case study on a commercial AD translation of an action comic series X: Big Badto explore translation strategies as norms that specifically facilitate achieving coherence and are unique to the cross-modal translation of comics, aiming at providing theorised guidelines for future practices. Based on visual language and narratology analysis, three types of visible interventions in AD comics translation are identified, challenging the notion of neutrality in AD and arguing that reasonable additions and adaptations can facilitate the target text’s accessibility
The Impact of Physical Activity Intensity on the Dynamic Progression of Cardiometabolic Multimorbidity: Prospective Cohort Study Using UK Biobank Data
Authors: Liu Bao-Peng , Zhu Jia-Hui , Wan Li-Peng , Zhao Zhen-Yu , Wang Xinting , Jia Cun-Xian
Published: September 2023

Background

Although many studies have reported on the associations between the amount of physical activity (PA) and the transitions of cardiometabolic multimorbidity (CMM), the evidence for PA intensity has not been fully evaluated.

Objective

This study aimed to explore the impact of PA intensity on the dynamic progression of CMM.

Methods

The prospective cohort of this study using data from the UK Biobank included 359,773 participants aged 37-73 years who were recruited from 22 centers between 2006 and 2010. The diagnoses of CMM, which included the copresence of type 2 diabetes (T2D), ischemic heart disease, and stroke, were obtained from first occurrence fields provided by the UK Biobank, which included data from primary care, hospital inpatient record, self-reported medical condition, and death registers. The PA intensity was assessed by the proportion of vigorous PA (VPA) to moderate to vigorous PA (MVPA). Multistate models were used to evaluate the effect of PA intensity on the dynamic progression of CMM. The first model (model A) included 5 transitions, namely free of cardiometabolic disease (CMD) to first occurrence of CMD (FCMD), free of CMD to death, FCMD to CMM, FCMD to mortality, and CMM to mortality. The other model (model B) used specific CMD, namely T2D, ischemic heart disease, and stroke, instead of FCMD and included 11 transitions in this study.

Results

The mean age of the included participants (N=359,773) was 55.82 (SD 8.12) years at baseline, and 54.55% (196,271/359,773) of the participants were female. Compared with the participants with no VPA, participants with intensity levels of >0.75 to <1 for VPA to MVPA had a 13% and 27% lower risk of transition from free of CMD to FCMD (hazard ratio [HR] 0.87, 95% CI 0.83-0.91) and mortality (HR 0.73, 95% CI 0.66-0.79) in model A, respectively. The HR for the participants with no moderate PA was 0.82 (95% CI 0.73-0.92) compared with no VPA. There was a substantially protective effect of higher PA intensity on the transitions from free of CMD to T2D and from T2D to mortality, which reveals the importance of PA intensity for the transitions of T2D. More PA and greater intensity had a synergistic effect on decreasing the risk of the transitions from free of CMD to FCMD and mortality. Male participants, younger adults, adults with a higher BMI, current or previous smokers, and excessive alcohol drinkers could obtain more benefits from higher PA intensity for the lower risk of at least 1 transition from free of CMD, then to CMM, and finally to mortality.

Conclusions

This study suggests that higher PA intensity is an effective measure for preventing CMM and mortality in the early period of CMM development. Relevant interventions related to higher PA intensity should be conducted.
Increasing the Bearing Capacity of Shallow Foundations on Soft Soil After the Installation of Micro-Piles
Authors: Isnaniati  , Mochtar Indrasurya B.
Published: September 2023

The bearing capacity of shallow foundations on soft soils can generally be estimated based on Local Shear Failure (Terzaghi theory). Several researchers previously stated that the installation of micro-piles on the failure area (slide) can increase the shear strength of the soil. This can be followed up by providing micro-pile reinforcement to prevent lateral soil movement. Therefore, this research was conducted to increase the bearing capacity of shallow foundations on medium-consistency soft clay soils that have been reinforced with micro piles. The research was conducted using modeling in the laboratory with a scale of 1:30. The soil sample used was kaolin clay made from slurry made from kaolin powder with a water content (wc = 1.77 LL), liquid limit (LL = 62.35%) and sample diameter (d = 33 cm). The slurry was formed by compacting at a medium consistency level with an undrained cohesion value (cu = 0.397 kg cm-2). The micro-pile material in the form of apus bamboo was installed, varying in diameter (d) 0.2 cm (0.027 B), 0.3 cm (0.04 B), and 0.5 cm (0.07 B); sum (n) 4, 9, 16, and 25; and length (L) 10 cm (1.33B), 13 cm (1.73B), and 16 cm (2.13B) micro-piles. While the foundation model uses a squarefoundation B x B with B = 7.5 cm. The tests were carried out before and after the micro-piles were reinforced with a soil shear failure test. The results showed that a decrease of 0.1B caused an increase in the ultimate bearing capacity of the micro-pile (qult-empirical, 0.1B) from the ultimate bearing capacity before installing the micro-pile. This value is then used to determine the ultimate bearing capacity ratio so that Rq,0.1B = qult-empirical,0.1B/qult-Terzaghi with the optimum bearing capacity ratio occurring at Rq,0.1B with n3 = 16, d2 = 0.04B, L2 = 1.73B.
Coastal and River Embankment Performance at Cengkareng Drain Estuary Under Compound Hazards Conditions Using HEC-RAS 2D
Authors: Hastomo Athena , Anggraheni Evi , Prasetyo Adi , Sutjiningsih Dwita , Pratama Mochamad Adhiraga , Umi Kalsum Atina
Published: September 2023

Jakarta is prone to pluvial, fluvial, and coastal flooding due to its geographical location and topography. In response to this problem, the Indonesian government has implemented several master plans, including the National Capital Integrated Coastal Development (NCICD). This ongoing program encompasses the construction of coastal and river embankment that stretch all over the coast of Jakarta. Since many coastal areas in Jakarta are residential or industrial, evaluating this performance of embankment has become crucial for effective flood management. The findings of this research can also support the development of other locations where NCICD embankment plan and enhance coastal resilience. Therefore, this research assessed the effectiveness of coastal and river embankment at Cengkareng Drain, a vital floodway in Jakarta, during extreme events that occur simultaneously. To simulate flooding events, two-dimensional HEC-RAS features were used to numerically calculate the area and depth of inundation. The simulation required geometry, terrain, land cover, and unsteady flow data. For the flow boundary conditions, a 100-year design rainfall, HHWL (Highest High Water Level), and 100-year design wave were considered to represent estuary conditions accurately. The simulation result showed that the maximum water level influenced by these factors was +3.145 mMSL, while the planned embankment top elevation was +3.40 mMSL. Furthermore, without the NCICD embankment, the simulation showed an inundation area of 1212.37 ha, which was reduced to 1111.22 ha after their implementation, leading to a decrease of 101.15 ha. This reduction significantly decreases potential damage to property and infrastructure, particularly in densely populated areas. The simulation also showed a reduction of 86.49 hectares or 66.22% in the inundation area with a depth exceeding 1 meter. These findings demonstrate the effectiveness of embankment in reducing the inundation area without any overtopping incidents.