bluuebunny/crossref_metadata_2025 huggingface dataset:
User Involvement in a Desire to Buy Particular Goods on the Internet
Authors:   Department of computer Applications  Chandigarh School of Business  Chandigarh group of colleges jhanjeri, Mohali,India
Published: April 2024

Social media can be very effective at promoting niche products because customers often enjoy leaving reviews and striking up discussions about these things. This could increase consumer interest in the goods. In this study, we investigate how user designs interacting during a discourse on a niche cultural product can affect engagement levels, which may in turn improve consumption intentions. We demonstrate how increased interaction might boost consumption motivation. We discover that increased homophily and connectedness within the social media network will lead to a simultaneous rise in polarization and the prevalence of content tailored to niche markets. Next, we examine an expansion in which two lobbyists have the ability and desire to affect the frequency of every kind of content. The primary ways in which businesses can use social media as tools for strategic marketing. The article outlines the primary categories of social media applications and suggests two key applications for social media use by marketers: As sources of market intelligence, or "passive marketing tools," as well as "active marketing tools," which are platforms for interacting, communicating, and promoting with customers.
Retos en el enfrentamiento del shock hipovolémico en el paciente politraumatizado
Authors: Torres Proaño María Fernanda , Madrid Peralta Erika Adriana , Hermida Pareja Diego Alexander , Bravo Orellana Katherine Isabel , Sellan Bustamante Víctor Manuel
Published: April 2024

Durante el reconocimiento y tratamiento de la hemorragia, que puede resultar potencialmente mortal en el paciente politraumatizado, se presentan desafíos para los profesionales en las diferentes etapas de la atención médica. Se realizó una revisión de la fisiopatología del shock hemorrágico y de las estrategias actuales de la conducta ante la pérdida aguda de sangre secundaria a trauma. En este sentido, se hizo énfasis en las lesiones que pueden pasar desapercibidas en la evaluación inicial y en la aparente compensación fisiológica. Se abordaron aspectos controversiales relacionados con la decisión en cuanto al momento oportuno y el modo adecuado de iniciar correctamente la reanimación con control de daños para evitar el empeoramiento de los trastornos graves inherentes a esta condición, como la acidosis y la coagulopatía inducida por el trauma y sus estados de hipo o hipercoagulabilidad (trombótico).  Se evaluó la controversia sobre la composición de los componentes que se transfunden durante la reanimación con control de daños, que justifica la tendencia en la práctica médica de transfundir con mayor frecuencia plasma liofilizado, en comparación con la de plasma fresco congelado compatible con ABO.
Tofacitinib citrate delivery through pharmaceutical formulations for divergent therapeutic treatments
Authors: Tabassum Sana , Makula Ajitha
Published: April 2024

The aim of article is to provide prompt and brief information on all available types of formulations of Tofacitinib citrate. Tofacitinib in the form of Tofacitinib citrate belongs to a new class of therapies called Janus kinase (JAK) inhibitors. Tofacitinib citrate is a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Tofacitinib is available in the form of a tablet, an extended-release tablet and as an oral solution. Janus kinase inhibitors (JAKi) belong to a new class of oral targeted disease-modifying drugs which have recently revolutionized the therapeutic panorama of rheumatoid arthritis (RA) and other immune-mediated diseases, placing alongside or even replacing conventional and biological drugs. This article elaborates on the information related to patents of Tofacitinib citrate for its formulation. A survey data for the marketed formulations of Tofacitinib citrate is tabulated.  Based on this it is estimated that very less type of formulations pertaining to conventional formulations as tablet or gel is only available in the market. Hence, there is an immediate demand for different type of tofacitinib formulations needed for treatment of extensive cases of arthritis or vitiligo. An extensive literature survey is done on pharmaceutical formulations of Tofacitinib citrate. Based on obtained data it was found these researched and developed formulations can be focused and further initiations can be done to make these formulations marketable. Wholesome, this article assists the reader to quickly grab information on marketed formulations and researched formulations of Tofacitinib citrate.
The Demographic and Clinical Characteristics of the Co-infection for the Detection of SARSCOV- 2 and Influenza A Virus by rRT-PCR
Authors: Khutade Kalpesh , Shah Harshada , Patil Samiksha , Patel Hiren
Published: April 2024

The potential for co-infection with COVID-19 and other respiratory infections raises the possibility that a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mimics the influenza A virus regarding methods and modes of transmission, clinical features, related immune responses, and seasonal coincidence. This study aimed to investigate the presence of SARS-CoV-2 and influenza A virus coinfections inadmitted patients of a tertiary care hospital. In this study, the total included 589 admitted patients in our tertiary care hospital. The detectionof co-infection between SARS-CoV-2 and influenza A virus by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) in a patientduring the second wave of the COVID-19 pandemic. There were 207 (35.1%) patients infected with SARS-CoV-2 and 43 (7.3%) patientsinfected with the influenza A virus. Only 6 (1.0%) patients were infected with SARS-CoV-2 and influenza A viruses. The females were morelikely to be infected with SARS-CoV-2 than non-infected SARS-CoV-2 case-patients (60.9% (n = 126) vs. 31.4% (n = 120), and also with theinfluenza A virus compared with influenza-negative patients (40.9% (n = 223) vs. 55.9% (n = 24). In conclusion, our results strongly suggestthat influenza A co-infects with SARS-CoV-2. The patients with SARS-CoV-2 and influenza A co-infection had similar clinical characteristics asthose with SARS-CoV-2 infection alone. Comorbidities, like hypertension and diabetes, and increasing age make patients more susceptible toSARS-CoV-2 and influenza A coinfections.
Synthesis of Metal Complexes of Substituted Isonicotinohydrazide and their Catalytic and Biological Activities
Authors: Pagar Nitin S. , Aher Abhishek B.
Published: April 2024

Coordination chemistry has fascinated and inspired chemists all over the world due to an increasing academic, industrial, and biological interest in metal complexes of organic chelating ligands. Among the chelating ligands, Schiff bases have attracted the attention of chemists due to ease of preparation and complexation. Numerous reports showed that a large number of isatin and its Schiff base metal complexes have excellent catalytic activity in a variety of reactions at mild reaction conditions and are used as homogeneous catalysts. Copper-based isatin complexes have found much attention because of their biological relevance. In this study, we report the synthesis of Schiff base metal complexes of substituted isonicotinohydrazide. The Schiff base, (C14H10N4O2) is prepared by condensing isoniazid with isatin. The complexes were synthesized in good yield from easily available metal precursors and characterized by UV-visible and FTIR spectroscopy. The Cu complex shows excellent activity for the C-N coupling reaction of the amination of aryl halides.  All four complexes show better antibacterial activity as compared to their corresponding [M (acac)n] complexes. In addition to this, the Co and Cu complexes such as [Co(C14H10N4O2)3] and Cu(C14H10N4O2)3] respectively show negative growth, towards Fusarium, and Aspergillus i.e. showing antifungal activity. The results were compared with the standard acetyl-acetone complexes of the same metals.
Hyperglycemic Crisis: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State
Authors: Kumar Pasupuleti K , Ruchitha Thokala , Varun Pasumala , Kumar Chinta R , Rama Rao Tadikonda
Published: April 2024

The two most severe metabolic consequences of diabetes mellitus (DM) are diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemia state (HHS). Type 1 and type 2 diabetics are both susceptible to these illnesses. Hyperglycemia, ketone body production, and metabolic acidosis are symptoms of DKA. Hyperosmolality, high blood glucose increase, and little to no ketosis are signs of HHS. Despite significant advancements, it has been difficult to come to a consensus on the diagnostic criteria and course of therapy for both disorders. Another difficulty is that there is a large overlap between these two extremities of the hyperglycemia crisis continuum. A thorough biochemical and clinical patient evaluation, along with prompt diagnosis and therapy, has long been recognized as being essential for symptom relief. Intravenous insulin, fluid replacement, and concurrent management of the triggering causes all form the cornerstones of therapy. Large-scale research that contributes to the definition of how hyperglycemic crises should be handled is lacking globally. A thorough analysis of the pathogenesis, diagnosis, and treatment of DKA and HHS will be provided in this article.
Survey of Medicinal and Invasive Weeds in Paddy Field – Phytochemical and GC-MS Profiling of Cyanotis axillaris R. & S.
Authors: Sharmila S , Kalaiyarasi S , Mownika S , Meghna KP
Published: April 2024

This study aims to determine the dominant weed species associated with rice crop fields in the Eppodhumvendran region of Thoothukudi district, Tamil Nadu and to analyze the phytochemicals, identify the bioactive compounds in ethanol extract using gas chromatography–mass spectrometry (GC-MS) and find their bioactivity using prediction of activity spectra for substances (PASS) prediction in Cyanotis axillaris. The documentation of medicinal weeds was carried out with the help of traditional local healers in Eppodhumvendran region. Phytochemical screening and GC-MS analysis of C. axillaris were performed to evaluate the chemical profiling of the extract. A total of 25 plant species regarded as invasive species/weeds were identified with the help of traditional local healers. The most commonly mentioned plant family was the Poaceae with a total of five species followed by the Euphorbiaceae, Asteraceae and Commelinaceae. Among these, C. axillaris is being studied for its potentiality due to its strong therapeutic value. The aerial plant part contains phytoconstituents such as alkaloids, glycosides, quinones, phenolics, steroids and terpenoids. The GC-MS results revealed 30 bioactive compounds, which were predicted using the PASS prediction method. The study highlights the importance of weeds in the paddy field ecosystem. The results reveal that C. axillaris contains various phytocomponents and that more research into their phytopharmaceutical relevance is required in the future.
Levels of Protein S in Saudi Patients with Myocardial Infarction
Authors: Elmissbah Tariq E , Aidrous Mohammed E , Al-Qahtani Fawwaz M , Alosaimi Amal S
Published: April 2024

A heart attack - also known as a myocardial infarction (MI) or acute myocardial infarction (AMI)—happens when blood supply to a part of the heart stops, resulting in heart muscle damage. Coronary artery disease is the leading cause of MI. Risk factors include smoking, diabetes, lack of exercise, obesity, high blood pressure, poor diet, and excessive alcohol consumption. Protein S, a vitamin K-dependent protein, functions as a cofactor for activated protein C (APC), allowing it to inactivate factors Va and VIIIa more effectively. This study examines levels of protein S in Saudi patients with myocardial infarction. A case-control study was performed to estimate the level of protein S in Saudi patients with MI. A total of 150 samples (2.5/mL of venous blood) from patients with MI and healthy controls (n = 50) were obtained and analyzed using an enzyme-linked immunosorbent assay (ELISA) sandwich. Patients’ mean protein S levels were within normal ranges (86.19.63 and 76.2030.64, respectively). Patients and controls had no significant difference in mean antithrombin (ATIII) and protein C levels (p-value = 0.26, 0.2, and 0.19, respectively). The findings also revealed that certain samples had low ATIII (8.7%) and protein C levels (11.3% ). From this study, we conclude that protein S deficiency was not found to be a major risk factor for MI.
Phenytoin-Induced Ataxia and Diplopia in a Patient with Recent Subarachnoid Hemorrhage: A Case Report
Authors: Karra Geetha , Smaigdhini Chunchu , Sahithya Udtha L , Sree Kotti R , Rao T Rama
Published: April 2024

This case report presents a 25-year-old male with a complex medical history, including a recent subarachnoid hemorrhage (SAH) and a prescription for phenytoin. The patient exhibited neurological symptoms, such as ataxia, blurring of vision, and diplopia, prompting an intricate diagnostic evaluation. The medical history encompassed a prior road traffic accident resulting in a jaw injury, adding to the complexity of potential aetiologies, including cerebellar dysfunction, sequelae from the accidents, medication-related side effects (particularly phenytoin), or infectious/inflammatory causes. Given the reported symptoms, there arose a suspicion of phenytoin-induced ataxia and diplopia, common neurological side effects associated with this anticonvulsant. These symptoms, suggestive of cerebellar dysfunction, required a comprehensive examination, including neurological assessments and imaging studies, to elucidate the precise etiology. This case underscores the importance of meticulous medication review, particularly for drugs like phenytoin, and emphasizes the necessity of a multidisciplinary approach involving neurologists to navigate the complexities associated with neurological manifestations in the context of SAH and medication use. The findings contribute to understanding potential complications arising from anticonvulsant therapy in SAH patients and highlight the need for tailored diagnostic and management strategies in such intricate clinical scenarios.
Formulation and Evaluation of Polyherbal Antidiabetic Capsules
Authors: Karra Geetha , Bhavani Vudutha , Kiran RS , Rao TR
Published: April 2024

This research aims to create and assess polyherbal anti-diabetic capsules using medicinal plants with anti-diabetic properties. The formulation process involves carefully choosing botanical extracts with antidiabetic properties, verifying their bioactive compounds, and blending them to form a polyherbal blend with maximum antidiabetic potential while ensuring safety.Micro Crystalline Cellulose is used in encapsulating a polyherbal mix for stability, release, and patient convenience. Capsule dosage form is recommended for improved treatment adherence. Efficiency is assessed through in vitro studies on enzymes involved in glucose metabolism and their inhibitory effect.The results of this study offer a viable natural option for managing diabetes by providing important insights into the composition of polyherbal antidiabetic capsules. Several botanical extracts with complimentary modes of action have the potential to be combined, offering a comprehensive strategy to address the complex nature of diabetes mellitus. Nevertheless, more clinical studies including diabetes patients are necessary to confirm the long-term advantages, safety, and effectiveness of the capsules. The creation of polyherbal antidiabetic capsules may present novel approaches to the management of diabetes, enhancing glycaemic control and elevating the standard of living for those with the condition.
Perancangan Aplikasi Kompresi File MP3 Dengan Menggunakan Algoritma Lempel Ziv Welch (LZW)
Authors: Betsaida Situmorang Tia
Published: April 2024

File berbentuk suara  banyak digunakan dalam kegiatan sehari-hari orang dalam mendukung aktifitasnya seperti penggunaan file suara dalam aplikasi pemutar musik baik secara daring maupun luring serta pada aplikasi audio streaming. Pemanfaatan tekniki kompresi suara sangatlah di butuhkan mengingat panjangnya durasi suara dan banyak nya file suara dalam ruang penyimpanan sehingga membutuh ruang penyimpanan yang banyak pula. Teknik kompresi merupakan teknik dimana kapasitas secara fisik file suara dikurangi dengan mengusahakan tidak mengurangi kualitas suara yang terdapat dalam file audio. File suara dengan ekstensi MP3 merupakan ekstensi file suara yang banyak digunakan saat ini, yang memiliki kepanjangan MPEG Audio Layer III. Menangani permasalah ruangan penyimpanan dan sekaligus menghemat penggunaan paket data pada saat melakukan pengaksesan sekaligus transimis file suara, maka diterapkan metode kompresi. Metode kompresi yang digunakan adalah Algoritma Lempel Ziv Welch (LZW). Algoritma Lempel Ziv Welch adalah algoritma kompresi yang menjaga kualitas dan mampu mengidentifkasi dan mengganti pola berulang dalam data. Penelitian ini diharapkan bisa dimanfaatkan untuk pengurangan ukuran data suatu file gambar dan video. Pada tahap awal yang akan dianalisa penulis ialah dengan mencari file Mp3 yang akan dikompres kemudian diubah menjadi nilai hexadecimal melalui aplikasi HxD. Setelah didapat nilai hexadecimal file Mp3 maka akan dilakukan proses kompresi dan diperoleh file hasil kompresi.  Hasil kompresi file audio dengan algoritma LZW diperoleh nilai Compression Ratio 16%.
Analisa Perbandingan Algortima Fibonacci Code Dan Rice Code Dalam Kompresi File Teks
Authors: Jelita Ratna
Published: April 2024

Kebutuhan kapasitas media penyimpanan file yang semakin besar merupakan penyebab terjadinya kemunculan berbagai teknik kompresi. Sehingga dengan dilakukannya kompresi, data yang ukurannya besar akan menjadi kecil dapat menghemat kapasitas media penyimpanan dan juga mempercepat dalam mentrasnfer file. Kompresi bertujuan untuk mengurangi redudansi data menjadi sekecil mungkin. Untuk mengatasi permasalahan ini yaitu dengan mengetahui algoritma yang lebih efisien dalam melakukan kompresi file teks bereksistensi (*.txt) dan dalam penelitian ini juga membandingkan antara algoritma Fibonacci Code dan Rice Code berdasarkan parameter yang sudah ditentukan. Setiap algoritma memiliki hasil perbandingan yang berbeda baik itu dari algoritma Fibonacci Code maupun algoritma Rice Code. Seperti yang diketahui dari algoritma keduanya memiliki hasil nilai akhir dengan menggunakan Metode Perbandingan Eksponential, hasil nilai akhir algoritma Fibonacci Code adalah 5,577 sedangkan hasil nilai akhir algoritma Rice Code adalah 5,466. Dan semakin besar total nilai yang dihasilkan maka semakin tinggi jumlah usaha yang dilakukan algoritma tersebut. Berdasarkan analisa tersebut maka dapat ditentukan algoritma Fibonacci Code yang memiliki kinerja terbaik dalam melakukan kompresi file teks.
Two-Pass Weed Management Programs for Identity-Preserved Soybean
Authors: Soltani Nader , Shropshire Christy , Sikkema Peter H.
Published: April 2024

Weed management is a challenge in Identity-Preserved (IP) soybean in Ontario, Canada. Six experiments were established in southwestern Ontario, Canada during 2021 and 2022 to evaluate weed control and soybean yield with preemergence (PRE), early postemergence (EPOST), and PRE followed by (fb) late POST (LPOST) herbicide programs. At 8 weeks after LPOST herbicide applications, S-metolachlor/metribuzin, pyroxasulfone/sulfentrazone, and flumioxazin/metribuzin/imazethapyr applied PRE provided 7, 49, and 99% control of velvetleaf; 65, 98, and 100% control of green pigweed; 7, 8, and 82% control of common ragweed; 25, 68, and 98% control of common lambsquarters; 91, 77, and 89% control of barnyardgrass; and 62, 68, and 93% control of green foxtail, respectively. Imazethapyr + bentazon applied EPOST provided 91% control of velvetleaf; 91% control of green pigweed; 78% control of common ragweed; 95% control of common lambsquarters; 76% control of barnyardgrass; and 79% control of green foxtail. S-metolachlor/metribuzin, pyroxasulfone/sulfentrazone, and flumioxazin/metribuzin/imazethapyr applied PRE fb bentazon + fomesafen + quizalofop applied LPOST provided 61, 86, and 100% control of velvetleaf; 97, 99, and 100% control of green pigweed; 94, 88, and 99% control of common ragweed; 96, 98, and 100% control of common lambsquarters; 97, 95, and 97% control of barnyardgrass; and 97, 96, and 99% control of green foxtail, respectively. There was minimal and transient soybean injury (6% or less) with all PRE or EPOST herbicide treatments, however, S-metolachlor/metribuzin, pyroxasulfone/sulfentrazone, or flumioxazin/metribuzin/imazethapyr applied PRE fb bentazon + fomesafen + quizalofop LPOST caused up to 22% injury in soybean. Weed interference reduced soybean yield 40%. Weed interference with S-metolachlor/metribuzin and pyroxasulfone/sulfentrazone applied PRE reduced soybean yield 25 and 31%, respectively. Reduced weed interference with flumioxazin/metribuzin/imazethapyr applied PRE, imazethapyr + bentazon applied EPOST, and the two-pass programs of a PRE fb LPOST herbicide resulted in soybean yield that was similar to the weed-free control. This study concludes that there are many effective weed management programs in IP soybean; however, the two-pass weed control programs are recommended since they provide good to excellent weed control, minimize soybean yield loss from weed interference, and ensure the use of multiple herbicide modes of action which reduces the selection intensity for the evolution of herbicide-resistant weeds.
Bridging Gaps: Pre-Service Mathematics Teachers’ Handling the Difficulties in Posing Real-World Mathematical Problems
Authors: Tangkawsakul Sakon , Thaikam Weerawat , Ugsonkid Songchai
Published: April 2024

Real-world mathematical problem (RWMP) solving and posing are important aspects of teaching and learning mathematical modelling, as well as developing a mathematization disposition for both teachers and students. Several researchers have explored blockages or difficulties in such modelling processes and in problem posing. However, prior research has identified difficulties that the pre-service mathematics teachers (PSMTs) encountered when they tried to pose a modelling problem by choosing the general topic themselves, as there is little known about possible obstacles that PSMTs can encounter when trying to pose a real-world problem relevant to a given mathematical topic. The current study explored the difficulties encountered by PSMTs in a RWMP-posing activity. The target group was 23 PSMTs with prior experience in mathematical modelling and mathematical problem posing. The findings showed that the PSMTs struggled with: (a) task organization, which involved selecting and understanding mathematical knowledge; (b) specialized content knowledge, which included a lack of real-world knowledge and difficulty in connecting mathematical concepts to real-world contexts; and (c) individual considerations of aptness, which encompassed authenticity, interest, complexity, language, and relevance to task organization. The PSMTs applied various strategies to complete the posing task, such as using problem-posing and solving heuristics, adapting existing problems, sharing and discussing with friends, and considering the perspective of a typical student. The implications of these findings should help in developing preparatory instructional practices for mathematics teachers.
Need Assessment of Education Management According to Sub-District Non-Formal and Informal Education Centre Standards for Excellence
Authors: Arsathong Sanit , Julsuwan Suwat
Published: April 2024

This study aims to study the Current Conditions, Desirable Conditions, and Necessary Needs of Educational Management according to standards for Excellence of Sub – District Non – Formal and Informal Education Centre. And to study educational management guidelines according to the Sub – District Non – Formal and Informal Education Centre Standards for Excellence. There were two steps: Step 1: Study the Current Conditions, Desirable Conditions, and Needs of educational management standards of Sub – District Non – Formal and Informal Education Centre Standards for Excellence. The sample consisted of 40 school administrators and 328 of the heads of Sub – District Non – Formal and Informal Education Centre, a total of 368 attended in the academic year 2022 using Multi-stage Random Sampling. Step 2: Study the standard educational management guidelines. The informants are qualified by studying best practices from five Models of Sub – District Non – Formal and Informal Education Centres, two persons, totaling ten people, by specific sampling. The research instruments: 1) The Current Conditions and Desirable Conditions Questionnaire following educational management according to standards for Excellence of Sub–District Non–Formal and Informal Education Centre, a 5-level rating scale. 2) Semi-structured interview 3) The Educational Management Approach Assessment Form is a 5-level estimation scale with statistics used to analyze the data, including mean, standard deviation, priority sorting of PNImodified data, and content analysis. The results showed that 1) the current condition as a whole and in terms of study is at a high level; Overall desirable conditions are at the highest level. One aspect is at the highest level: six are at the highest level. Considering the necessary needs, it found that the needs of educational management according to the standards. There is a need to develop all seven areas as follows Organizational Leadership, Strategic Planning, Learner and Stakeholder Focus, Knowledge Analysis and Management Measurement, Processing Management, and Personnel Focus. 2) the suggestions were seven aspects and 135 approaches as follows Workshops, Learning from other people, Brainstorming, Operating Integration, Mentoring, and Learning from successful organizations.
ERNet : Enhanced ResNet for classification of breast histopathological images
Authors: J Kamalakannan , R K Chandana Mani
Published: April 2024

Inspite of expeditious approaches in field of breast cancer, histopathological analysis is considered as gold standard in diagnosis of cancer. Researchers are working tremendously to automate the detection and analysis of breast histology images, which confess in improving the accuracy and also induce the mimisation of processing time. Deep learning models are providing greater contribution in solving several image classification tasks. In this paper we propose a model to classify breast histological images, which is redesigned from existing ResNet architecture that minimises model parameters and increase computational efficiency. This approach uses enhanced ResNet connection instead of identity shortcut connection used in ResNet architecture. We apply our proposed method on BreakHis dataset and achieve an accuracy around 95.92 %.  The numerical results show that our proposed approach outperforms the previous methods with respect to sensitivity and accuracy.
Substitution Patterns of the English Voiced Interdental Fricative by L1 Costa Rican Spanish Speakers
Authors: Fonseca Quesada Felix
Published: April 2024

L1 Spanish speakers learning English struggle to produce the English voiced interdental fricative [ð]. This is surprising as [ð] occurs naturally in Spanish as an intervocalic allophone of /d/. To investigate Spanish speakers’ production of [ð] in English, I conducted a study with ten L1 Costa Rican Spanish/L2 English speakers. The results show that English voiced interdental fricatives were produced with target pronunciation 43.4% (214/494) of the time and were substituted in the remaining 56.6% (280/494). It was determined that target-sound substitution patterns depend on the phonological contexts in which the target sound occurs (word-initial vs. intervocalic), and the type of speaking task (reading vs. spontaneous). I interpret these results as partially due to phonological transfer: L1 allophonic information affects L2 speech production. The results also show that the realization of the segments is affected by the different experimental tasks: speakers have more target-like production in tasks where there is an opportunity for more careful pronunciation (reading task) than in more spontaneous ones. Finally, I argue that the unexpected appearance of the alveolar tap [ɾ] is due to an interaction between the English /d/ tapping allophone rule and the status of [d] and [ð] in the learner’s interlanguage.
Application of Teaching Strategies and Methods in Science and Social Studies Classes
Authors: Letina Alena
Published: April 2024

The paper presents the results of a survey which aimed to determine the preferences of primary school class teachers toward student-centred or teacher-centred teaching strategies and methods, the frequency with which they are used in science and social studies classes, and the correlation between these variables. The research was conducted on a sample of 301 class teachers from the Republic of Croatia. The results indicate that teachers prefer student-centred teaching strategies and methods. Despite of that, in their teaching practice they employ teacher-centred teaching strategies and methods significantly more frequently in terms of statistics, especially in the realisation of the learning outcomes set by the curriculum in the main part of the lesson. Moreover, a positive correlation between the teachers' opinion about the application of certain teaching strategies and methods and the frequency of their use has been determined. The implications of the obtained results for future research on this topic, as well as for the advancement and further modernisation of primary science and social studies teaching, are considered in the conclusion.
Teacher's Work with Children with Special Needs in Kindergarten
Authors: Mithans Monika , Lipovec Živa , Ograjšek Sabina
Published: April 2024

The preschool period is a susceptible stage of children's development, and it is essential that children receive the necessary support for their optimal development during this period. This is especially important for children with special educational needs. The present study highlights the importance of early childhood education teachers and teacher assistants to provide optimal conditions for the development of children with special educational needs. Our research includes 148 early childhood education teachers and teacher assistants, who completed a questionnaire about the general tasks they perform when working with children with special educational needs. The results show that while teachers perform various tasks intended for children with special educational needs and cooperate with the kindergarten counselling service, parents and other professionals, they do not feel competent to work with children with special educational needs. Additionally, the results indicate that there are differences between early childhood education teachers and teacher assistants, as the results are more favourable for the former.
Desarrollo de un modelo experimental de fibrosis inducida por obstrucción ureteral unilateral (OUU) en ratones
Authors: Escobar Camila
Published: April 2024

Comprender los mecanismos que rigen la fibrosis renal es crucial debido a que se trata de una vía final común para la mayoría de las formas de enfermedad renal crónica (ERC). Dentro de las mismas, la nefropatía obstructiva es una entidad muy frecuente e implica la necesidad de contar con modelos de estudio adecuados.

El modelo de obstrucción ureteral unilateral (OUU) en ratones demostró ser útil para estudiar la progresión de la nefropatía obstructiva hacia la fibrosis renal. Sin embargo, esta cirugía no ha sido llevada a cabo en el laboratorio de la UAI.

El objetivo general fue establecer un modelo experimental de fibrosis inducida por OUU en ratones. Para ello, se utilizaron ratones hembra adultas de la línea C57BL/6J, que fueron sometidas a un procedimiento quirúrgico durante el cual el uréter izquierdo fue doblemente ligado con seda quirúrgica y luego cortado entre ambas ligaduras. Luego de 2 semanas se evaluó el daño renal, bioquímica e histológicamente.

En este trabajo se demostraron cambios morfológicos tanto macroscópicos y microscópicos en el riñón izquierdo cuyo uréter fue intervenido. El modelo de desarrollo de fibrosis por OUU realizado en este estudio es factible, reproducible y de utilidad para el estudio de patologías renales obstructivas.
Den judiska släkten Reiniger i 1700- och det tidiga 1800-talets Prag
Authors: Fürth Thomas
Published: April 2024

Den österrikiske kejsaren Joseph II tvingade judarna 1787 i sitt rike att överge sina patronymikon och anta släktnamn. Lagen genomfördes omedelbart i den bömiska provinsen. Men i Prag hade judiska familjer sedan 1600-talet använt sig av andra tillnamn än patronymikon. Dessa kunde ärvas från en generation till annan men kunde likaväl växla inom en generation. Syskon kunde använda olika tillnamn. Ibland användes de tillsammans med patronymikon men inte alltid. Pragjudarnas tillnamn följde vissa mönster. De kunde hänvisa till exempelvis yrke eller ursprungsort. I den följande artikeln visas hur en judisk familjs yrken och ursprungsort bestämde deras tillnamn, vilket gjort det möjligt att fastställa släktlinjer bak till 1700-talets början trots att släktmedlemmar använde olika tillnamn och dessutom växlade mellan olika tillnamn under sin levnad.
Underlagmannen Anders Eriksson i Vålsta, Forsa socken och hans släktkrets
Authors: Sverker Thomas
Published: April 2024

I denna utredning behandlas underlagmannen i Hälsingland, Anders Eriksson, från Vålsta i Forsa socken i samma landskap. Karriären kartläggs: han började som fogdetjänare 1581, blev sedan underlagman och slutligen, 1605, fogde i Lappmarken upp emot Västersjön. Detta innebar att hans avslutande verksamhetsområde var allra längst norrut i riket, i Västersjöns Finnmark (från Tipisfjord till Varanger). Här tecknas hans biografi, den närmaste släktkretsen utreds och hans hustrus fäderne kartläggs. Slutligen presenteras barnen med korta sammanfattande biografier.
Síndrome de Burnout em Profissionais de Saúde que Atuam em Unidades de Terapia Intensiva: uma revisão integrativa
Authors: Lacerda Giovanna Maria Oliveira de , Neves Lauana Rocha de Lima , Wilk Mirce Meire Gonçalves de Sousa
Published: April 2024

Objetivo: Identificar os fatores de risco que podem contribuir para o desenvolvimento da síndrome em profissionais de saúde que atuam em unidades de terapia intensiva. Métodos: Trata-se de revisão integrativa da literatura, a partir da estratégia de busca nas seguintes bases de dados: SciELO (Scientific Eletronic Library Online), LILACS (Literatura Latino Americana e do Caribe em Ciências da Saúde, e Medline (Medical Literature Analitics and Retrieval System Online). Resultados:  Compuseram a amostra final cinco estudos publicados entre janeiro de 2010 e agosto de 2023, das bases SciELO e Medline. A prevalência da síndrome variou com a categoria profissional, sexo, idade, nível educacional e estado civil, sendo mais prevalente no sexo feminino. A existência de fatores de risco como a quantidade de pacientes assistidos e a possibilidade de complicações, ruídos excessivos, lidar com sofrimento e morte, cuidado a pacientes em estado terminal e remuneração insuficiente, favoreceram o desenvolvimento da síndrome. Conclusão: A coexistência de fatores pessoais, organizacionais, sociais e do trabalho que constituem risco para o desenvolvimento da síndrome de burnout, colocam profissionais de saúde atuantes em UTI em vulnerabilidade diante do desenvolvimento da síndrome. A adoção de medidas para o enfrentamento mostra-se benéficas.
Gestão de enfermagem, um olhar para unidade de terapia intensiva: revisão integrativa da literatura
Authors: Silva Nara Suelly Lira , Maciel Maria da Piedade Gomes de Souza , Amorim Filho Fabius Jorge Rosas Marques Luz de , Barbosa Vanessa Gabriella Bernardino , Santos Juliana Silva dos
Published: April 2024

A gestão em enfermagem perpassa por planejar, organizar, dirigir, controlar e aplicar processos de trabalhos para atender as necessidades dos serviços em saúde de forma a acompanhar o dinamismo que a profissão requer. Objetivo: Analisar as evidências científicas, sobre gestão de enfermagem com um olhar para a unidade de terapia intensiva. Método: Trata-se de uma revisão integrativa, sendo a coleta de dados realizada no período de setembro de 2023 a janeiro de 2024, através da leitura e análise de artigos publicados nos últimos 10 anos, na língua portuguesa, gratuitos, disponíveis integralmente na forma on line, na base de dados Scielo e google acadêmico. Resultados: Os artigos analisados evidenciam que são muitos os desafios para o bom desempenho de um enfermeiro gestor, indo desde a necessidade de aprimoramento técnico científico a habilidade de gerenciar conflitos e prover boas condições de trabalho. Conclusão: O mundo moderno requer do enfermeiro gestor a atualização constante de suas práticas, apropriação do aparato tecnológico, exercitar a habilidade de ouvir, respeitar a equipe de modo a gerenciar conflitos e acompanhar as transformações dinâmicas do mundo do trabalho.
Diagnóstico auxiliado por computação para identificação de anemias
Authors: Corrêa Junior Cleber de Almeida , Corrêa Rosilene Abreu Portella , Kamp Márcio Eccard Kort , Camp Lucas de Souza Kort
Published: April 2024

Esse trabalho propõe o uso de redes neurais artificiais (RNAs) na identificação de quadros de anemia por meio de análise de exames de sangue do tipo hemograma completo. Esse procedimento é geralmente realizado por médicos. Entretanto, esse presente trabalho investiga a possibilidade de tal diagnostico ser sistematizado para poder ser fornecido por computadores, funcionando como um auxiliador do médico no momento do diagnóstico.
Análise físico-química e sensorial da produção de geleia de pimenta produzida com a pectina do albedo do maracujá
Authors: Silva Angelica Campos , Mata Lara Alves da , Melo Jose Douglas da Gama , Rodrigues Filho Delson Pinto
Published: April 2024

O albedo do maracujá é um subproduto rico em pectina, sendo uma das principais fibras solúveis do fruto, tornando excelente para produção de geleias. A pimenta dedo de moça é considerada dentre os alimentos funcionais benéfica para a saúde, devido à sua complexidade de nutrientes. Em geleias fica bastante interessante, conferindo um sabor agridoce. O estudo visou produzir uma geleia de pimenta dedo de moça utilizando pectina extraída do albedo de maracujá; Foram conduzidas análises físico-químicas, microbiológicas, sensoriais e bromatológicas para avaliar a qualidade do produto. Três formulações foram testadas, sendo selecionada a melhor em termos de sabor e textura. Os resultados das análises físico-químicas mostraram pH de 3,2, sólidos solúveis de 62% Brix, umidade de 46,2%, acidez titulável de 1,02%, teores médios de sódio de 174mg/100g e ácido ascórbico de 4,4mg/100g. Nas análises bromatológicas, os resultados para carboidratos (46,8%), fibras (1,82%), proteínas (2,68%) e lipídios (1,82%). Os resultados das analises microbiológicas deram ausentes. O teste sensorial, com 50 participantes, obteve uma aceitação superior a 70% pelo indice de aceitação ,IA.Para os resultados estatisticos usou o Microsoft Excel para média e desvio Padrão e oprograma Minitab para eboborar o grafico Bloxplot representando as notas dadas pelos julgadores em cada atribulto. O rótulo nutricional seguiu regulamentações específicas da RDC 429 e IN 75. A utilização da casca de maracujá para extração de pectina mostrou-se econômica e sustentável, reduzindo resíduos. Concluiu-se que a geleia de pimenta apresenta potencial para comercialização, elaborada em conformidade com padrões de higiene e fabricação.
Narrativas de professores sobre africanidades no currículo e produção da diferença no Colégio do Campo Miguel Arcanjo, Sítio do Mato, BA
Authors: Pereira Pricila Oliveira , Ferreira Maria de Fátima de Andrade
Published: April 2024

O presente artigo apresenta um recorte de uma dissertação realizada durante formação no curso de pós-graduação Mestrado em Ensino (PPGEn) pela Universidade Estadual do Sudoeste da Bahia (UESB). A pesquisa analisou narrativas de professores sobre africanidades como componente eletivo no currículo e produção da diferença do Novo Ensino Médio do Colégio Estadual do Campo Miguel Arcanjo (CECMA), Sítio do Mato, BA, situado em uma comunidade camponesa ribeirinha, que faz parte do município de Sítio do Mato, localizada no interior da região Oeste do estado da Bahia e que pertence ao Território de Identidade Velho Chico. Nesse sentido, a pesquisa buscou analisar as estratégias pedagógicas e curriculares aplicadas pelo campo investigado para desenvolver educação para as relações étnico-raciais, observando, por meio da análise das narrativas dos professores, interlocutores da pesquisa, quais os sentidos de negro/não negro são produzidos/reproduzidos na sala de aula e de que modo o componente eletivo Africanidades, que faz parte do currículo flexível do Novo Ensino Médio, contribui (ou não) para o combate contra preconceitos/discriminação étnico-racial, racismo, entre alunos no contexto escolar. Os procedimentos de coleta de dados foram realizados por meio da aplicação de entrevista semiestruturada e formulários, com perguntas fechadas e abertas flexíveis, conversas informais com as interlocutoras e observação in loco, direta e sistemática, com questões que dialogam com a perspectiva teórica do estudo. Este artigo apresenta parte da análise e interpretação de dados coletados pela entrevista semiestruturada. O que foi aqui mostrado possui respaldo teórico-metodológico, principalmente, nos Estudos Culturais (Hall, 2006; Silva, 1999, 2000), e nos estudos sobre a decolonialidade, pedagogia decolonial (Costa; Torres; Grosfoguel, 2018; Mota Neto, 2016, dentre outros). Conforme os resultados e procedimentos de análise e interpretação de dados, com respaldo no aporte teórico dos Estudos Culturais e perspectivas sobre relações étnico-raciais, algumas conclusões sobre as narrativas de professores sobre africanidades como componente eletivo no currículo e produção da diferença do Novo Ensino Médio do Colégio Estadual do Campo Miguel Arcanjo - CECMA, Sítio do Mato, BA foram apontadas: a identidade e produção da diferença, a introdução da disciplina eletiva de Africanidades possibilitou que as temáticas começassem a ser discutidas no colégio de forma mais aprofundada, gerando transformações nas formas de pensar/falar/agir dos professores e estudantes.
Caracterização da intensidade da dor de pacientes infantojuvenis e sua relação com mucosite oral induzida por antineoplásico
Authors: Dantas Fernanda Suely Barros , Pessoa Katarina Haluli Jano da Veiga , Pinho Ana Caroline Sabino , Silva Kezia Maria Dias , Melo Júnior William Alves de , Leão Jair Carneiro , Carvalho Januse Nogueira de , Carvalho Alessandra de Albuquerque Tavares
Published: April 2024

O câncer infanto-juvenil corresponde a um grupo de várias doenças que têm em comum a proliferação descontrolada de células anormais e que pode ocorrer em qualquer local do organismo. O objetivo geral desta pesquisa é caracterizar a intensidade da dor e sua relação com a mucosite oral em crianças e adolescentes em tratamento quimioterápico internadas no setor de Oncologia Pediátrica em um hospital de referência regional público do município de Campina Grande, PB. Trata-se de um estudo transversal com abordagem quantitativa, onde a amostra foi selecionada por conveniência. Neste estudo foram utilizados como instrumentos para a coleta dos dados, um formulário sociodemográfico, a Escala Visual e Analógica de dor EVA, a escala de gradação da Mucosite Oral da Organização Mundial de Saúde (WHO) e a Escala Internacional de a Avaliação de Mucosite Oral em Crianças (ChiMES). No presente estudo foi possível observar uma forte correlação positiva entre as variáveis grau de mucosite e o escore ChiMES aplicado nas crianças (τ= ,717**), sugerindo que quanto maior foi o grau de mucosite maior o escore ChiMES aplicado nas crianças(p≤0,01), uma forte correlação positiva entre as variáveis grau de mucosite e o escore ChiMES dos pais (τ= ,713**) e uma correlação moderada positiva entre as variáveis grau de mucosite e o escore EVA (τ= ,680**). A partir da realização da pesquisa, pode-se concluir que os pacientes não apresentaram fortes sintomatologia dolorosa em relação a MO, talvez isso tenha ocorrido devido a alguns dos pacientes terem realizados a terapia de fotobiomodulação durante o tratamento antineoplásico.
O novo ICMS educação no estado de Santa Catarina: diferenciações em escala maior e menor
Authors: Bona Juliano
Published: April 2024

Com a implementação da Lei no 18.489, que regulamenta a forma metodológica de repasse do ICMS Educação de Santa Catarina, várias iniciativas no campo das gestões educacionais em nível de município passaram a ser tomadas. O ambiente competitivo criado por meio da metodologia que atrela indicadores educacionais a repasses monetários, tem o potencial de criar outros contornos em diferentes escalas. Nesse sentido, nosso objetivo é ampliar as discussões referentes ao novo ICMS Educação que já está em curso no ano de 2023. Em uma escala maior, molar, analisamos os impactos do novo ICMS Educação de forma ampla, a grelha metodológica que atinge de forma simultânea os 295 municípios catarinenses. O pano de fundo neoliberal permite edificar as justificativas, a articulação entre lógica empresarial, competitividade e qualidade na educação. Em uma escala menor, molecular, mostramos os deslocamentos de adaptabilidade das gestões educacionais e a racionalidade vinculada a neogestão. Além da matematização dos dados flutuantes que legitima os processos, as gestões escolares e suas ações, estão em constante processo de alinhamento a racionalidade neoliberal, onde os sujeitos que ali atuam, por sua vez, se articulam as planilhas, a vigilância constante dos números. Estamos diante do problema das velocidades, a rápida resposta a este novo contexto de repasse pode maximizar os abismos entre as redes e escolas públicas do Estado, as que tem maior capacidade material de resposta já em 2023 tem o potencial de criar distâncias que podem, sem cuidado, tornar-se irreversíveis.
Assistência ao parto e nascimento por enfermeiras residentes de obstetrícia: estudo em duas maternidades sergipanas
Authors: Santos Ana Priscila , Oliveira Valéria Patricia Gama , Borges Cristiani Ludmila Mendes Sousa , Silva Alexia Augusta de Oliveira
Published: April 2024

Este estudo objetiva descrever as vivências de enfermeiras residentes em obstetrícia na assistência ao parto e nascimento em duas maternidades sergipanas. Trata-se de um estudo descritivo com abordagem quantitativa e qualitativa, desenvolvido em duas instituições de atendimento obstétrico, no período de março de 2020 a março de 2021. Como participantes, 11 residentes de enfermagem obstétrica responderam à entrevista semiestruturada. Obtiveram-se como resultados 82,7% da utilização de técnicas respiratórias, 81,5% das parturientes deambularam, 70,4% das mulheres tomaram banho de aspersão com água morna, dentre a aplicação dos métodos não farmacológicos de alívio da dor. Além disso, a ausência de episiotomia foi evidenciada. A autonomia diante da condução do parto foi registrada na maioria das assistências. Considerando o impacto da pandemia da doença do coronavírus sobre a assistência obstétrica, constataram-se limitações no tocante ao auxílio dos movimentos inerentes ao ato de partejar. Em soma, a atuação das enfermeiras residentes teve como princípio a aplicação das boas práticas de atenção ao parto, melhorando o desfecho parturitivo, permitindo o protagonismo das mulheres e o resgate de partos fisiológicos, além da redução de intervenções desnecessárias.