bluuebunny/crossref_metadata_2025 huggingface dataset:
Supporting Innovative Activities of College Teachers
Authors:   Rybinsk Polygraphic College, Varzanova Mariya А.
Published: December 2020

The article substantiates the urgency of supporting innovative activities development by secondary vocational education workers. The study is aimed at finding the causes of difficulties and justifying the support of innovative activities of teachers. Its purpose is also to determine the conditions and stages, and to identify the means of support. The scientific novelty of the article lies in the fact that a complex of organizational and pedagogical conditions that provide support for innovative activities is highlighted. It also includes diagnostics of innovative activities development level, motivational support, differentiated and individualized training of teachers, and organization of teachers' joint innovation activities. Based on domestic research, the stages of teachers support are identified. They include preparatory, motivational, self-diagnostic, goal-setting, and planning. Self-realization and intensification of teachers practical activities, independent innovation and a reflective-analytical stage are also emphasized. The means of accompaniment at each stage are listed: direct participation in innovation, research, implementation of innovative projects, contextual training, methodological and psychological support, introspection, and reflection. The author describes the results of diagnostics of teachers in relation to innovations, carried out using a set of techniques aimed at identifying individual characteristics of the perception of innovations. The most numerous groups are distinguished: teachers with a negative attitude, teachers who are neutral in relation to innovations, and teachers with a positive attitude; ready to implement innovations and teachers who are at a creative level.
The Social and Economic Impact of COVID 19 Pandemic on Museums. Case Study: „Princely Court” National Museum Ensemble
Authors:   „Valahia” University – Targoviste/ I.O.S.U.D/S.D.S.I, Targoviste, Romania, Nastase Mihai-Claudiu , Mitru Alexandru ,   „Valahia” University – Targoviste/ I.O.S.U.D./S.D.S.I., Targoviste, Romania, Paun (Parnic) Loredana Andreea ,   „Valahia” University – Targoviste/ I.O.S.U.D./S.D.S.I., Targoviste, Romania
Published: December 2020

The new coronavirus (Covid-19) is one of the main challenges world today has to address. With no large scale availability vaccine yet, and more or less experimental medical treatments for curing the disease, we can safely say that we are still far behind a solution to this problem. This new pandemic is considered the biggest threat to the global economy since the Second World War and there is no aspects of human life have not been affected it, spiritual ones included. Its high contagiousness, as well as novelty, raised all kind of challenges and one of the main ones was our manner to produce answers, in early stages at least, this creating problem on its own and of its design. As well as all the other institutions, theatres, cinemas, concert halls, spaces of socialization and in the same time places of wonder, knowledge and spiritual enrichment the museums were heavily affected by the pandemic crisis, especially those who’s collections are not, but in very small proportion available, to the public through virtual media. Such a case is „Princely Court„ National Museums Ensemble from Targoviste, Dambovita County, Romania. The present paper proposes an overview of the highlights in institution′s activity the past years in comparison with how the pandemic crisis affected its activity in the past months and what were the responses given to keep the museum in the eye of the public. It will also try to summarize how and to what extent the activity went back to „normal” after the emergency state earlier imposed was lifted and how the visitors responded to the new realities.
Trabalho, direitos inerentes ao trabalho, direito do trabalho e constituição da república: o significado humano, social e político da reforma trabalhista
Authors: Almeida Cleber Lucio , Almeida Wânia Guimarães Rabêllo
Published: December 2020

A pretexto de modernizar o Direito do Trabalho, atrair investimentos estrangeiros e fomentar a competitividade das empresas e, com isso, retomar o crescimento econômico e a criação de empregos, foi realizada, no Brasil, a denominada reforma trabalhista. Este artigo adota como metodologia a revisão bibliográfica e o método dedutivo e define o significado humano, jurídico, social e político da reforma trabalhista, que permite considerá-la um projeto político neoliberal que institui uma nova ordem jurídica, social, econômica e política, contrária àquela definida pela Constituição a partir do lugar que atribui ao trabalho, aos direitos trabalhistas e ao Direito do Trabalho.

Palavras-chaves: Reforma trabalhista; significado humano, social e político.
Emergenze e ordinamento costituzionale italiano
Authors: Adamo Ugo , Gambino Silvio
Published: December 2020

A contribuição propõe uma análise crítica das consequências que podem ser determinadas no ordenamento jurídico constitucional sobre a ocorrência de emergências que requeiram a adoção de medidas cabíveis para enfrentá-las. Nessa perspectiva, o estudo leva em consideração as emergências terroristas e de saúde. Assim, avalia as diferenças e semelhanças nestes contextos, devido às inúmeras consequências que as decisões adotadas produzem no equilíbrio entre as liberdades individuais e os interesses coletivos, sobre o sistema de fontes, e a forma de Estado e de governo. O sistema constitucional se mantém se for concreto e se a democracia for madura. Com a ocorrência dessas condições, é possível limitar os direitos em equilíbrio com os demais direitos, respeitando-se o que é reconhecido pelo mesmo sistema constitutivo. Isso pode ser visto nos desenvolvimentos jurídicos ocorridos em alguns países europeus, como a Polônia e a Hungria, que exploram a crise pandêmica para questionar o Estado de Direito.
Emergência de respostas de ouvinte após ensino de intraverbais em um menino com Autismo
Authors: Silva Elaine de Carvalho , Caixeta Luiza Magalhães , Elias Nassim Chamel
Published: December 2020

A literatura tem indicado que intervenções que utilizam os princípios da Análise do Comportamento Aplicada têm produzido resultados promissores para solucionar questões referentes aos déficits nas habilidades de linguagens apresentados por crianças com Transtorno do Espectro Autista (TEA). Considerando que as dificuldades de comunicação prejudicam a qualidade de vida destas crianças, justifica-se o ensino de repertórios de falante (linguagem expressiva) e de ouvinte (linguagem receptiva). Visto que estes repertórios são funcionalmente independentes, o presente estudo utilizou procedimentos de Instrução com Múltiplos Exemplares para promover interdependência do ensino de respostas intraverbais (“Que mão é esta”? – resposta: “Direita”) na emergência de respostas de ouvinte (“Mostre a mão direita”). O objetivo foi verificar os efeitos do ensino de respostas intraverbais de dizer direita ou esquerda para questões referentes ao lado de uma parte do corpo (repertório de falante) na emergência de respostas de ouvinte envolvendo as mesmas partes do corpo (braços, mãos, orelhas e pernas) e relações espaciais de direita e esquerda em um menino verbal de seis anos de idade com TEA. Foi verificada também a generalização dessas relações para objetos no ambiente. Os resultados indicaram que o treino de respostas intraverbais promoveu a emergência de respostas de ouvinte de seguir instrução para o participante, o que confirma uma das rotas de ensino descritas na literatura (falante-ouvinte).
Emergência de intraverbais a partir do treino de tatos com Precision Teaching
Authors: Moraes Priscilla Terumi , Coimbra Cláudia Stefânia Figueiredo Neves
Published: December 2020

Indivíduos com TEA (Transtorno do Espectro do Autismo) podem apresentar dificuldades de comunicação, tais como déficits na emissão de intraverbais durante interação social. Ao longo dos anos, pesquisadores vêm testando diversos procedimentos para o ensino desta habilidade (Kodak, Fuchtman e Paden (2012); McMorrow, Foxx, Faw, e Bittle (1987); Cihon, White, Zimmerman, Gesick, Stordahl & Eshleman (2017)). Este trabalho objetivou avaliar se o ensino de tatos tematicamente relacionados a níveis fluentes poderia resultar na emergência de intraverbais. Utilizou-se delineamento de linha de base múltipla entre categorias, de sujeito único, e foram realizadas cinco etapas de ensino: (1) treino de tato, (2) treino de fluência de tato, (3) sonda de persistência (endurance), (4) sonda de estabilidade (stability) e (5) sonda de retenção (retention). Os resultados indicaram que a habilidade intraverbal emergiu a partir do treino fluente de tatos tematicamente relacionados com uso de Ensino Preciso (Precision Teaching), sem necessidade de treino direto. Estudos futuros podem investigar a emergência com indivíduos que não emitem intraverbais para nenhuma categoria, e também comparar o tempo de aquisição entre o treino direto e o treino de fluência de tato com um mesmo sujeito. O presente estudo apresenta limitações quanto ao contexto no qual foi realizado e participante (setting terapêutico e história de reforçamento de seguir instruções), e quanto à forma de apresentação dos estímulos (sinalização das categorias temporal e visualmente).
La Partida de Bautismo y el Estado Civil de las personas
Authors: Tubino Mongilardi Fidel
Published: December 2020

Trataré el siguiente punto: la partida de Bautismo es una certificación pública (eclesiástica) de que tal persona, fué bautizada: éste es el hecho primariamente atestiguado, pero junto con él se consignan otras circunstancias, apellido, paternidad, maternidad, legitimidad. ¿Cuáles son las relaciones entre el hecho certificado del bautismo y los adminículos jurídicos del bautizado?
El Apostolado a través de la profesión
Authors: Rosell Ríos José
Published: December 2020

No contiene resumen
Rendición de Cuentas
Authors: Dammert Bellido José
Published: December 2020

No contiene resumen
Couture y su obra procesal
Authors: Sentis Melendo Santiago
Published: December 2020

No contiene resumen
"Agency" en el Derecho Norteamericano
Authors: Llona Bemal Alvaro
Published: December 2020

No contiene resumen
La "Corporation"
Authors: Gubbins Forero Guillermo
Published: December 2020

No contiene resumen
La Enseñanza del Derecho Aéreo en el Mundo
Authors: Pépin Eugéne
Published: December 2020

No contiene resumen
El Federalismo Norteamericano y el Derecho Internacional
Authors: Carl Beverly May
Published: December 2020

No contiene resumen
El Contrato de Aparcería
Authors: Gazzolo Luis
Published: December 2020

El artículo no presenta resumen.
El Profano y la Ley en Inglaterra
Authors: Kemp Allen Carlton
Published: December 2020

El artículo no presenta resumen.
Desarrollo Histórico del Derecho internacional
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
Derecho de familia en la Unión Soviética
Authors: Kos-Rabcewicz Zubkowski Ludwik
Published: December 2020

No contiene resumen
Expropiación forzosa
Authors: Barros Conti César
Published: December 2020

No contiene resumen
El Dominio Marítimo
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
La protección de las inversiones extranjeras
Authors: García-Mora Manuel
Published: December 2020

No contiene resumen
Comentarios al Código de Procedimientos Penales: El Ministerio Público
Authors: García Rada Domingo
Published: December 2020

No contiene resumen
Los antecedentes históricos y comparativos del Código Civil Griego
Authors: Zepos Panayotis
Published: December 2020

No contiene resumen
Dominio Territorial
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
La empresa agrícola
Authors: Gazzolo Luis
Published: December 2020

No contiene resumen
La Unidad del Derecho Privado en Luisiana durante el Régimen Español
Authors: Batiza Rodolfo
Published: December 2020

No contiene resumen
Prontuario del Impuesto de Alcabala de Enajenaciones
Authors: Belaúnde Guinassi Manuel
Published: December 2020

No contiene resumen
La pena de muerte en Inglaterra
Authors: Cooper H. H. A.
Published: December 2020

No contiene resumen
La capitalización de intereses
Authors: Vidal Ramírez Fernando
Published: December 2020

No contiene resumen
La profesión de abogado como objeto de estudio
Authors: Zolezzi Ibarcena Lorenzo
Published: December 2020

No contiene resumen
La lógica del deber ser y su eliminidad
Authors: Miró Quesada Cantuarias Francisco
Published: December 2020

No contiene resumen
La lucha contra el crimen y el tratamiento correccional
Authors: Altmann Smythe Julio
Published: December 2020

No contiene resumen
El Derecho y la naturaleza de las cosas
Authors: Alzamora Valdez Mario
Published: December 2020

No contiene resumen
El concepto de renta en la legislación tributaria
Authors: Medrano Cornejo Humberto
Published: December 2020

No presenta resumen
Protección procesal de los derechos fundamentales en la constitución peruana de 1979
Authors: García Belaúnde Domingo
Published: December 2020

No presenta resumen
Fundamentación filosófica de los derechos humanos
Authors: Miró Quesada Cantuarias Francisco
Published: December 2020

No presenta resumen
La cuestión de las islas Malvinas
Authors: Ochoa Reyes Ana
Published: December 2020

El trabajo se inicia realizando un cuidadoso rastreo de los principales hechos históricos y de ocupación en torno a las Islas Malvinas, desde su descubrimiento en el siglo XVI, hasta los años problemáticos del siglo XIX en que los territorios son tomados colonialmente por Inglaterra. El segundo capítulo hace un análisis crítico de los diferentes títulos de soberanía que, a partir de los hechos anteriores, reclaman para sí la Gran Bretaña y la República Argentina. Del estudio se concluye que los títulos legítimos corresponden a la Argentina.Finalmente, se hace una extensa referencia al tratamiento que el problema de las Islas Malvinas ha tenido en el debate internacional, preferentemente en las Naciones Unidas. Detalle especial sehace en relación a los principios de la Descolonización, la Libre determinación y la Integridad Territorial,aplicados al caso bajo estudio.
Compensación por tiempo de servicios
Authors: Álvarez Ramírez de Piérola Fernando
Published: December 2020

No presenta resumen
Naturaleza jurídica del contrato de Joint Venture
Authors: Pastor Argumedo Reynaldo
Published: December 2020

No presenta resumen
Las ganancias obtenidas por las personas jurídicas no domiciliadas cuando venden acciones
Authors: Hernández Berenguel Luis
Published: December 2020

El presente trabajo pretende efectuar un análisis estrictamente técnico del tema en función de las normas actualmente vigentes y sólo referencialmente se hará mención de la jurisprudencia que recayó cuando estaba en vigor el régimen del Decreto Supremo N" 287-68-HC.
Las entidades emisoras de valores negociables en bolsa
Authors: Vidal Ramírez Fernando
Published: December 2020

No contiene resumen
Constitución para un Brasil nuevo
Authors: Dallari Dalmo
Published: December 2020

No contiene resumen
El constitucionalismo peruano en la presente centuria
Authors: García Belaunde Domingo
Published: December 2020

No contiene resumen
Las relaciones entre los órganos de gobierno en la constitución del Perú: un modelo hibrido entre el presidencialismo y el parlamentarismo
Authors: Fernández Segado Francisco
Published: December 2020

No contiene resumen
Constitucion, derecho y principios penales
Authors: Prado Saldarriaga Victor
Published: December 2020

No contiene resumen
La medida cautelar en la acción de amparo
Authors: Abad Yupanqui Samuel
Published: December 2020

No contiene resumen
La doctrina de los actos propios en el derecho civil peruano
Authors: Ortiz Caballero René
Published: December 2020

No contiene resumen
Formas de participación en negocios ajenos
Authors: García Noriega Wilfredo
Published: December 2020

No contiene resumen
La función de la pena en el código penal de 1991
Authors: Prado Saldarriaga Victor
Published: December 2020

No contiene resumen
El tipo penal de robo en el nuevo código penal peruano 1991
Authors: Aguirre Chumbimuni Javier
Published: December 2020

No contiene resumen
México, la constitución y las situaciones de emergencia
Authors: Carpizo Jorge
Published: December 2020

No contiene resumen
Comentarios al decreto ley 26122 sobre represión de la competencia desleal
Authors: Kresajla Baldo
Published: December 2020

No contiene resumen
Las reivindicaciones de la patente de invención
Authors: Bercovitz Alberto
Published: December 2020

No contiene resumen
Del derecho de quiebra al derecho concursal moderno y la ley de reestructuración empresarial
Authors: Ferrero Diez Canseco Alfredo
Published: December 2020

No contiene resumen
Legitimidad para obrar
Authors: Viale Salazar Fausto
Published: December 2020

No contiene resumen
Derecho electoral: aspectos jurídicos y técnicos
Authors: Landa Arroyo César
Published: December 2020

No contiene resumen
Los problemas de las limitaciones de responsabilidad en el campo de los transportes de mercancías
Authors: Lazo Víctor
Published: December 2020

No presenta resumen
El despido en la reforma de la ley de Fomento del Empleo
Authors: Blancas Bustamante Carlos
Published: December 2020

No presenta resumen
El Derecho como tema literario. Discurso de incorporación a la Academia Peruana de la Lengua
Authors: Trazegnies Granda Fernando de
Published: December 2020

No presenta resumen
Study on Residue Management Options in Combine Harvested Rice Field in Relation to Yield and Economic Benefits of Succeeding Rice Crop
Authors: Vijayaprabhakar A. , Durairaj S. Nalliah , Hemalatha M. , Joseph M.
Published: December 2020

Background: Paddy straw is a good source of plant nutrients. In-situ incorporation of paddy straw affects the growth and development of succeeding rice crop by immobilization of soil available nutrients. To overcome this, paddy straw incorporated with additives and its effect on rice growth and development was studied. Methods: A field experiment was conducted at Agricultural College and Research Institute, Killikulam during October 2014 to February 2015, to study the residue management options in combine harvested rice and its effect on yield and economic benefits of rice crop. The experiment was laid out in Randomized Block Design and replicated thrice. The treatments comprised rice residue without and with additives (25 kg additional N ha-1 as basal, bio-mineralizer (2 kg t-1 rice residue), cow dung slurry (5%). The additives applied individually, combination of two and combination of all additives. Result: Different rice residue management practices exerted significant influence on succeeding rice crop. Increased number of productive tillers (409), number of grains per panicle (162), panicle length (23.8 cm), number of filled grains per panicle (132) and spikelet filled percentage (87) was recorded by T8, where straw incorporated with application of 25 kg additional N ha-1 as basal + bio-mineralizer (2 kg t-1 of rice residue) + cow dung slurry (5%). The same treatment recorded highest grain yield of 7395 kg ha-1 and straw yield of 8440 kg ha-1 and it reflected as maximum value of ₹ 1,13,646 ha-1 , 69,079 ha-1 and 2.55 of gross return, net return and B:C ratio, respectively.
YÖNETİCİ VE ÖĞRETMENLER GÖZÜNDEN BİLSEM’LERDE VERİLEN EĞİTİMİN KRİTİĞİ
Authors: YILMAZ Metin , YILMAZ Tuncay
Published: December 2020

Teknolojiyi, sanatı, bilimi üretecek nitelikli insan yetiştirebilen toplumlar çağının ötesine geçebilmiş ve diğer toplumlara yön vermişlerdir. Bu bağlamda bilimsel ve yenilikçi eğitim anlayışı ile sanat, müzik, bilim, siyasi ve askeri alanlarda önde gelen bireyler yetiştirmişlerdir. Bunu yaparken de üstün yetenekli bireyleri gözden kaçırmadan bireysel farklılıklarına göre düzenlemeler yapmışlardır. Alan yazımda ülkemizde de üstün yetenekli öğrencilerin eğitimleri ile ilgili birçok çalışma mevcuttur. Özellikle 2000’li yıllardan sonra ülkemizde yaygınlaşmaya başlayan Bilim ve Sanat Merkezleri (BİLSEM) bu çalışmalara konu olmuştur. Bu çalışmada Türkiye'deki üstün yetenekli çocukların eğitimi, BİLSEM bünyesinde görev yapan yönetici ve öğretmenlerin bakış açıları ile ele alınmış ve değerlendirilmiştir. Araştırma nitel bir durum çalışmasıdır. Ulaşılan veriler NVIVO Pro 12 nitel veri analizi yazılım programı ile analiz edilmiştir. Çalışma sonucunda, BİLSEM’in öğrencilerin yaratıcılığına olumlu katkı sunduğu, bireyselliği öne çıkardığı, eleştirel düşünme becerisini desteklediği sonuçlarına ulaşılmıştır. Eksiklikler olarak eğitim programlarının teorik alt yapısının yetersiz olması, öğrencilerin spesifik ihtiyacını karşılamaktan uzak olması, eğitim alan çocukların psikolojik gelişimlerini destekleyici unsurların olmaması; disiplinler arası ve çok yönlü düşünmeyi destekleyen faaliyetlerin de yapılması gerektiği ortaya çıkmıştır.
Vonnegut, Darwin, and the Tragical Satirical Arc of Human History in the Novel "Galapagos"
Authors: Robinson David
Published: December 2020

In 1985 Kurt Vonnegut produced a satirical novel entitled Galapagos, in which the author explored a possible earth set one million years in the future. Human beings “have quietly evolved into sleek, furry creatures with flippers, and small brains.”[1]

Vonnegut posits a world in which human logic, derived from the functioning of three-kilogramme brains, has resulted in the downfall of the species, prior to the evolution of the seal-like creatures. This article explores the novel from an ecocritical perspective, including references to the work of Greg Garrard, Rachel Carson and Arne Naess. Charles Darwin’s work is also considered because the novel’s title and setting allude to his work on evolution.

This article will argue that Vonnegut believes human beings should change their thought and behaviour patterns if we are to have an optimistic future.

[1] This quote is from the blurb on the back cover of the Flamingo edition, 1994.
papel dos articuladores na configuração da revista “A Escola” (1906-1910)
Authors: Nascimento Maria Isabel Moura , Zanlorenzi Claudia Maria Petchak , Leal Sandra do Rocio Ferreira
Published: December 2020

O presente artigo tem por objetivo analisar o papel dos articuladores que publicavam na revista “A Escola”. Esse periódico (1906-1910), fonte primária dessa investigação, será analisado na perspectiva da totalidade da história, pois é parte de um projeto maior denominado de Imprensa e Educação. A utilização do vocábulo “articuladores” deve-se ao fato de que não se pretende entrar na história dos intelectuais sobre os quais há diversos estudos.  A revista em foco é um periódico de cunho educacional que apresenta dois arranjos ideológicos: educação e imprensa. É por meio desses arranjos que se pretende concretizar o objetivo do artigo em tela, que é apresentar como se processa a construção da cidadania[i] no contexto do Paraná, por meio dos principais articuladores da revista educacional “A Escola”, na formação do professor. Os exemplares da Revista “A Escola” se encontram, atualmente, na Biblioteca Pública do Paraná (Divisão Estadual) e na Hemeroteca Digital do Rio de Janeiro (disponível em: bndigital.bn.gov.br/hemeroteca-digital). A fonte primária é a revista “A Escola”.
compêndio geografia para quarta série secundária (1938) de Aroldo de Azevedo sob a perspectiva da organização do trabalho didático
Authors: Oshiro Jane das Dores Guimarães , Centeno Carla Villamaina
Published: December 2020

Este trabalho analisa o compêndio intitulado Geografia, 6ª edição (1938), destinado à quarta série secundária, de autoria de Aroldo de Azevedo. Objetivamos apreender o papel desempenhado por essa obra no ensino secundário. Para tanto, elegemos como categoria central a organização do trabalho didático, formulada por Gilberto Luiz Alves. No que se refere à metodologia, procedemos à revisão bibliográfica de trabalhos sobre a formação intelectual, experiência profissional e produção literária de Aroldo de Azevedo e de estudiosos da área da História da Educação e da legislação educacional pertinente. Verificamos que a obra analisada se trata de um compêndio, precisamente de um compêndio em transição, pois certas características evidenciam a aproximação com o manual didático.
Financial control and growth of private primary schools in Kenya
Authors: Njiiri Julius Muthike , Mwenja Dominic , Kiambati Kellen , Mbugua Levi
Published: December 2020

Proper management of finances in private primary schools is very imperative to their operations. There are, however, serious financial challenges in these private schools in Kenya as characterized by unprecedented high fees charged on students. The objective of this study was to assess the role of financial control in the growth of private primary schools in Kenya. The study was guided by the Cash Management Theory that gives emphasis to reasonable ways to deal with organizational finance management and efficient utilization as well as the Endogenous Growth Theory which stipulates that, in the long-run growth rate depends on a stable business environment. The study employed both quantitative and qualitative study design, which targeted 7,418 private primary schools in Kenya. Accessible population constituted of 3,431 heads of schools in four regions of Kenya namely: Nairobi, Central Kenya, Northeastern, and the Coastal regions. A random sampling method was used to draw a sample of 320 respondents who were either the principals’/Head teachers or deputy principal of the schools. A structured questionnaire was used to collect data. Structural Equation modeling using Analysis of Moment Structures was used to analyze the data. The fitness of the hypothesized structural and measurement models was tested using the Normed Fit Index and the Root Mean Squared Error. The overall path coefficients obtained were positive and significant at a 0.05 level of significance. The study established that financial control positively and significantly influenced the growth of private primary schools. The study recommended that private primary schools should have effective budget management mechanisms and strong financial controls.
Almost Global Stability of Nonlinear Switched System with Stable and Unstable Subsystems
Authors: Kivilcim Aysegul , Karabacak Ozkan , Wisniewski Rafal
Published: December 2020

This paper presents sufficient conditions for almost global stability of nonlinear switched systems consisting of both stable and unstable subsystems. Techniques from the stability analysis of switched systems have been combined with the multiple Lyapunov density approach - recently proposed by the authors for the almost global stability of nonlinear switched systems composed of stable subsystems. By using slow switching for stable subsystems and fast switching for unstable subsystems lower and upper bounds for mode-dependent average dwell times are obtained. In addition to that, by allowing each subsystem to perform slow switching and using some restrictions on total operation time of unstable subsystems and stable subsystems, we have obtained a lower bound for an average dwell time.
The Legal Stability as a Factor of Economic and Financial Market Growth: Russia, USA and China
Authors: Chikulaev Roman
Published: December 2020

Global economy, financial markets and technology are on the verge of moving to a new stage of development – information society. Three major world countries the US, Russia and China will play a leading role in this process. However, the specific development path will depend on many factors, including the stability of legal systems, security of computer and financial technologies, the effectiveness of legislation. The focus of this article is to assess the current condition of the economy the major countries, to identify trends and methods of stabilization of legal systems on the basis of balance of rights and obligations of the business, suggest some methods of objective evaluation of the impact factors of the total taxes, fixed costs and the legal system dynamics on financial indicators.
Infectious mononucleosis in children: clinical and laboratory characteristics depending on the disease etiology and phase of infection
Authors:   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Demina O.I. , Chebotareva T.A. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Mazankova L.N. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Tetova V.B. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation,   Peoples' Friendship University of Russia (RUDN University), Moscow, Russian Federation, Uchaeva O.N. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
Published: December 2020

Objective. To assess the association between clinical and laboratory characteristics of infectious mononucleosis (IM) and disease etiology and phase of infection. Patients and methods. This prospective observational study was conducted at Z.A.Bashlyaeva Children's City Clinical Hospital, Moscow Healthcare Department and included 107 children with IM. Laboratory testing was performed at the Department of Virological Diagnostics, National Medical Research Center for Hematology, Ministry of Health of the Russian Federation. Results. IM is a polyetiologic disease. So far, researchers have failed to find a significant correlation between clinical manifestations of IM and its etiology and phase of infection. Patients with IM caused by primary monoinfection with Epstein–Barr virus (EBV) are at high risk of developing chronic EBV infection. Neutrophilia is a typical laboratory sign of IM during the acute phase of it. Conclusion. The improvement of IM diagnosis with a detailed evaluation of clinical and laboratory criteria, as well as risk assessment of unfavorable outcome are currently impossible without the identification of both disease etiology and phase of infection. Key words: human herpes virus VI, Epstein–Barr virus, children, infectious mononucleosis, cytomegalovirus
Maintenance and testing protocols in the railway industry
Authors: Massaro Alessandro , Cannella Emanuele , Dipierro Giovanni , Galiano Angelo , D’Andrea Giovanni , Malito Giorgio
Published: December 2020

This paper introduces new maintenance and testing protocols regarding processes in the railway industry. The first protocol is general and can be applied to industries working in similar production processes. The second and third protocols are more specific to the railway industry and concern the turning-machine production line and the pneumatic testing of train braking systems, respectively. This study has been conducted within the framework of industry research on the design of intelligent control and actuation systems suitable for auto-adaptive Industry 5.0 facilities.
Novel concepts and strategies in skull base reconstruction after endoscopic endonasal surgery
Authors: Solari Domenico , Papallo Ida , Ugga Lorenzo , Cavallo Luigi M. , Onofrio Ilaria , Cuocolo Renato , Improta Giovanni , Brunetti Arturo , Martorelli Massimo , Gloria Antonio , Cappabianca Paolo , Russo Teresa
Published: December 2020

Recently, a variety of craniofacial approaches has been adopted to enter the skull base, among those, the endonasal endoscopic technique. An effective watertight thereafter:  the reconstruction can be performed using different materials, both autologous and non-autologous, individually or combined in a multilayer fashion. The current study was focused on the development of new advanced devices and techniques, aiding in reducing postoperative CSF leak rate. Additive manufacturing allows the design of devices with tailored structural and functional features and, as well, injectable semi-IPNs and composites; therefore specific mechanical/rheological and injectability studies are valuable. Accordingly, we propose  new additive-manufactured and injectable devices.
Methodology of Defining of the Radiation Therapy Components for Various Methods of Patients’ Treating Using Medical Linear Accelerators and Gamma-Therapeutic Devices
Authors: Titovich E. V. , Piatkevich M. N. , Makarava N. I.
Published: December 2020

One of the main factors affecting the effectiveness of radiation therapy is the constancy of the patient’s position on the treatment table created by immobilization devices of various designs and held throughout the entire irradiation procedure, which guarantees the accuracy of the delivery of the prescribed dose distribution. The purpose of the work was to establish the numerical values of the dominant components of a radiation therapy session for each of the irradiation techniques most commonly used in clinical practice of the radiation therapy.

To determine the numerical values of the components of the radiation therapy session, the authors have measured each component for some clinical cases of patients’ irradiation placed. The patients had been diagnosed with the following malignant tumours: prostate cancer, breast cancer, lung cancer, head and neck tumours. More than 2000 individual measurements have been carried out with the help of such medical linear accelerators as "Clinac", "Unique", "Truebeam", and the gamma-therapeutic apparatus named "Theratron".

The numerical values of the time spent on 3 groups of parameters of an irradiation session were established: the mechanical parameters of the radiation therapy equipment, the functional characteristics of the irradiation systems and the parameters that directly depend on the personnel involved in an irradiation procedure.

According to the measurement results, the flow diagram for the procedures of verifying a patient’s position on the therapeutic table (2 different techniques), preceding their irradiation and the radiation therapy procedures themselves was proposed. It has been shown that a number of session components can run in parallel to each other thus optimizing the time spent by a patient in the treatment room.

Using the obtained values of the time spent on the radiation session parameters it is possible to actualize the mathematical model that will allow the medical physicist to determine in advance the duration of the irradiation session at the stage of treatment planning and choose a radiation therapy technique taking into account the individual parameters of the irradiation session in each particular clinical case.
Effect of A Group Tobacco Cessation Behavioural Intervention Among Patients with Mental Illness in Kenya: Results from a Controlled Clinical Trial
Authors: Olando Yvonne , Mathai Muthoni , Kuria Mary , Njiri Francis , Huffman Mark
Published: December 2020

Background: Individuals with mental disorders are more susceptible to initiating and sustaining tobacco use; unfortunately, most do not get support to quit. Group behavioural counselling, an effective low-cost strategy for cessation has been shown to be effective, yet has not been studied among this population in Kenya.Methods: Mentally ill tobacco users at Mathari Referral and Teaching Hospital’s Clinic for Substance Abuse Treatment in Nairobi, were recruited from September 2017-March 2019. Participants were allocated into intervention and control groups (1:1). Intervention group participants met in groups of 10 over 24-weeks to participate in group behavioural counselling sessions using a structured curriculum to promote cessation. Control group participants received usual care. The primary outcome was tobacco cessation at 24-weeks measured through salivary cotinine strips. Secondary outcomes included self-reported number of cigarettes/sticks used daily and health-related quality of life (HRQoL), using the WHOQoL Brief Questionnaire at 24-weeks. Between-group event rates were compared using Cox proportional hazards models, while differences in HRQoL scores were analysed using paired t-tests.Results: Participants’ mean age was 35 (SD=9) years, 87% were male, and 42% had completed secondary education. Over half (65%) had substance use disorders (diagnosed) and 15% had major depressive disorders. Most participants (94%) used cigarettes at baseline and participants smoked for a mean of 13 (SD=11) years with an average of 14 (SD=7) sticks daily. Intervention group participants reported a higher cessation rate (15.2% vs. 0% at week 12;P=0.02 and 9.1% vs. 0%;P=0.10) at 24-weeks, with a lower number of sticks smoked (97% vs. 58.6%;P<0.0001) compared with control group participants at 24-weeks follow-up. Intervention group participants reported higher change in HRQoL scores compared to control participants in physical (30.6% vs. 10.4%;OR=3.79 [95% CI,1.25-11.48]) and environmental domains (34.7% vs. 8.3%;OR=5.84 [95% CI,1.79-19.03]) at end of study.Conclusion: The group behavioural intervention among tobacco using Kenyans with mental illness led to improved tobacco cessation outcomes. Trial registration number: NCT04013724
The role of postmastectomy radiation in patients with ypN0 breast cancer after neoadjuvant chemotherapy: a meta-analysis
Authors: Wang Ke , Jing Xiaoyan Xiaoyan , Wang Weilan , Yu Xiuyan , Huang Jian
Published: December 2020

Background: It has been demonstrated that postmastectomy radiation therapy (PMRT) was beneficial for breast cancer patients who are axillary lymph node-positive. However, the effectiveness of radiotherapy in pathological negative nodes (ypN0) after neoadjuvant chemotherapy (NAC) remains open to considerable debate. Here, we aim to evaluate whether PMRT improves loco-regional control and survival for such patients.Methods: The literature from January 2004 to June 2019 was searched. The effects of PMRT on local-regional recurrence (LRR) and survival was evaluated in a meta-analysis. Pooled relative risk (RR) values with 95% confidence intervals (CIs) were computed using random and fixed-effects models. Subgroup and heterogeneity analyses were also conducted.Results: Ten studies that included 29,860 patients met the inclusion criteria. Pooled results showed that PMRT was associated with reduced LRR (RR, 0.38; 95% CI, 0.19-0.77, P = 0.007), particularly in patients with stage III-IV breast cancer (RR, 0.16; 95% CI, 0.07-0.37, P < 0.001). However, no significant difference in disease-free survival were observed with the addition of PMRT for ypN0 patients (RR, 0.70; 95% CI, 0.21–2.27, P = 0.55). Also, there was no statistically significant association between radiotherapy with overall survival (RR, 0.81; 95% CI, 0.64-1.04, P = 0.10).Conclusions: Our meta-analysis indicated that PMRT might reduce local-regional recurrence for ypN0 patients after NAC, but lake of benefit for survival outcomes. Prospective randomized clinical trial data will be needed to confirm our results.
Changes in the use of after-hour house-call medical services for fever or common cold symptoms during the COVID-19 pandemic in Tokyo, Japan: a descriptive study
Authors: Inokuchi Ryota , Morita Kojiro , Iwagami Masao , Watanabe Taeko , Ishikawa Masatoshi , Tamiya Nanako
Published: December 2020

Background The trend in the characteristics of patients using an after-hour house-call (AHHC) medical service changed the coronavirus disease of 2019 (COVID-19) pandemic, but there has been no report on this issue since the start of the COVID-19 pandemic. The aim of this study was to investigate patients’ tendencies to seek an AHHC medical service for fever or common cold symptoms during the COVID-19 pandemic.Methods This cohort study compared the characteristics of patients with fever or symptoms of the common cold utilizing an AHHC medical service offered by a single large company between the control period (December 1, 2018 to April 30, 2019) and the COVID-19 pandemic exposure period (December 1, 2019 to April 30, 2020). It also assessed the proportion of these patients in relation to all patients calling for the service for any reason. Results During the control and COVID-19 pandemic exposure periods, 6,462 (median age: 8 [interquartile range {IQR}: 3, 11], males: 48.2%) and 10,003 (median age: 10 [IQR: 4, 33], males: 48.3%) patients, respectively, called for the AHHC medical service. Of these, 5,335 (82.6%) and 7,423 (74.2%) patients had fever or common cold symptoms, respectively. The disease severity was differently distributed between the groups: the proportions of people with severe, moderate, and mild illness were 0.3%, 28.7%, and 71.0% in the control period and 1.1%, 54.8%, and 44.1% in the COVID-19 pandemic exposure period (p < 0.001), respectively. The AHHC medical service identified six individuals with COVID-19.Conclusions During the COVID-19 pandemic, the proportion of patients with fever or symptoms of the common cold was lower than that in the control period, but the illness severity was substantially higher.
Short-term outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma in elderly patients: A propensity score matching analysis
Authors: Monden Kazuteru , Sadamori Hiroshi , Hioki Masayoshi , Ohno Satoshi , Takakura Norihisa
Published: December 2020

The number of elderly patients with hepatocellular carcinoma (HCC) requiring surgical treatment has been continuously increasing. This study aimed to examine the safety and feasibility of laparoscopic liver resection (LLR) versus open liver resection (OLR) for HCC in elderly patients at our institution in Japan.Between 2010 and 2018, LLR and OLR were performed in 80 and 138 elderly patients (>70 years) who were diagnosed with HCC, respectively. Propensity score matching (PSM) analysis with covariates of baseline characteristics was applied. Intra- and postoperative data were evaluated in both groups.After PSM, 56 patients who underwent LLR and OLR, respectively, were compared. No significant differences in demographic, clinical data, and operative times were observed. Blood loss (OLR: 327 mL; LLR: 50 mL; P< 0.001), length of postoperative hospital stay (OLR: 12 days; LLR: 7 days; P< 0.001), and time to start oral intake (OLR: 2 days; LLR: 1 day; P< 0.001) were significantly lower and shorter in the LLR group than in the OLR group. The incidence of complications over Clavien-Dindo class IIIa was similar between both groups.Our results suggest that advanced age alone is not a contraindication, and LLR can be a treatment option for elderly patients with HCC.
Circular RNA screening identifies circMYLK4 as a regulator of fast/slow myofibers in porcine skeletal muscles
Authors: Cao Haigang , Liu Jieming , Du Tianning , Liu Yihao , Zhang Xiaoyu , Guo Yuan , Wang Jie , Zhou Xiaomin , Li Xiao , Yang Gongshe , Shi Xine
Published: December 2020

Background: The myofiber type is related to the quality of meat; specifically, slow-oxidized myofiber helps to increase the tenderness and juiciness of meat. An increasing number of studies have shown that circRNAs play a key role in skeletal muscle development. However, the key circRNAs that regulate myofiber types and their roles are still poorly understood.Results: A total of 40757 circRNAs were identified from the longissimus dorsi (LD) and the soleus (Sol) muscles, of which 10388 were co-expressed in the two muscles. Further analysis found 181 differentially expressed circRNAs in the LD compared with Sol. Functional enrichment analysis showed that target genes of differentially expressed circRNA-sponge miRNAs were enriched in the AMPK, FoxO and PI3K-Akt signaling pathways. In addition, we focused on a novel circRNA—circMYLK4. CircMYLK4 significantly increased the mRNA and protein levels of slow muscle marker genes and caused the flesh to turn red.Conclusion: Our study laid an essential foundation for further research on circRNAs in myofiber type conversion and the achievement of higher meat quality.
Measurement of Empathy among Health Professionals During Syrian Crisis using the Syrian Empathy Scale
Authors: Dashash Mayssoon , Boubou Mounzer
Published: December 2020

Background: Health professionals should have certain degree of empathy to eliminate the pain and suffering of their patients. There is a need to design a scale, which can assess empathy among health professionals and is relevant to community and culture. Therefore, this study was undertaken to measure the empathy among Syrian health professionals and students of health professions using a newly designed Syrian Empathy Scale.Methods: A cross-sectional observational study was undertaken. A total of 223 participants (121 males and 102 females) responded to the Syrian Empathy Scale SES from Medical (n=62), Dental (n=152) and Pharmacy faculties (n=9). They were 119 undergraduates, 64 postgraduates and 40 general practitioners. The SES was designed as a tool that includes 20 items in a 7-point Likert-type scale with overall score ranges from 20 to 140. Group comparisons of the empathy scores were conducted using t-test and analysis of variance (ANOVA). A factor analysis was performed. Bartlett’s test of the sphericity and the KMO measure of sampling adequacy were also determined. Cronbach’s alpha was calculated.Results: A significant difference was found between males and females in the SES mean score. The ANOVA analysis showed that the SES empathy score of pharmacist was higher than medical doctors and dentists with no significant difference. The SES empathy score of undergraduates was significantly higher than postgraduates and practitioners. Findings of KMO indicated sampling adequacy (KMO= 0.827 > 0.7) and the value of Bartlett’s test of the sphericity (1288.76, df = 190, P-value<0.001) proved that the factor analysis is meaningful and acceptable. The results of varimax rotation proved that five main factors were retained.Conclusion: Findings of this study support the reliability of the newly designed Syrian Empathy Scale for measuring empathy in the field of health care. The SES can be suggested for assessing empathy in different health educational programs. However, future works are still essential to support the validity of the scale as well as to ascertain the role of empathy in improving health care.
Neonatal sepsis in southwest of Iran; prevalence of microbial pathogens, risk factors, clinical manifestations and laboratory findings
Authors: Salahi Marjan , Moghadam Abdolkarim Ghadimi , Mousavizadeh Ali , Marashifard Masoud , Taghavi Seyed Jabar , Rezanejad Mohamadtaher , Moradi Sedighe , Khoramrooz Seyed Sajjad
Published: December 2020

Background: Neonatal sepsis is a serious worldwide problem causing significant rates of mortality and morbidity in newborns, especially in cases with delayed infection diagnosis and management. The present study aimed to evaluate the bacteriological profiles, antibiotic susceptibility patterns, risk factors, clinical manifestations, and laboratory findings in neonatal sepsis in southwest of Iran. Methods: In this descriptive-analytic study, 342 neonates with suspected sepsis admitted to the neonatal ward and NICU were included. Using standard protocols, blood samples were transported to the BACTEC blood culture system. Then, conventional biochemical tests were used for the identification of bacterial genera and species. The bacterial antimicrobial susceptibility patterns were determined usingagardisk diffusion method according to the CLSI guidelines. Demographic data, clinical findings, risk factors, mortality rates, and laboratory parameters were collected for each patient. Results: Forty-three (12.6%) cases were culture-positive, among whichCoNS, Staphylococcus aureus, Escherichia coli, Acinetobacter and Beta hemolytic streptococcus were the most prevalent. The prevalence of early-onset sepsis and late-onset sepsis were 53.5% and 46.5%, respectively. Significant differences between prematurity, very low birth weight, and invasive procedures were observedbetween neonates with and without sepsis. Teicoplanin and vancomycin were the most efficient antibiotics against Gram-positive bacteria, while amikacinwas more efficient against Gram-negative bacteria. Conclusion: Risk factors such as prematurity, abnormal birth weight, anemia, leukopenia, prolonged hospitalization, and invasive processes and cesarean section, can increase the incidence of neonatal sepsis.