bluuebunny/crossref_metadata_2025 huggingface dataset:
Goethe’s voice in the novel of Andrei Nikolev “Beyond Tula”
Authors:   Novosibirsk State University of Economics and Management, Vasilyeva Galina M.
Published: June 2023

The paper examines the polygenetic nature of images and motives in the novel by Andrei Nikolev (Egunov), with particular attention on the “Faustian code”, which allows one to comprehend the European literary tradition. The writer is known to have been exceptionally passionate about Goethe’s works. He was close to the morphology of Goethe’s culture that drew the organizing world principle from the development of biological forms. Goethe’s ideas about the relationship between the cellular tissue of organisms and the expressive tissue of culture were a text-forming force in Egunov’s creativity. Goethe’s context covers a wide range of meanings: from the eschatological category of the transformation of phenomena and the world’s transformation to the farce, for example, in the story about the Hamelin piper. Nikolev’s novel has two realities overlapped without being autonomous and separate. Against the backdrop of the flickering plot of “Faust,” a plot twist appears: instead of a bet and a contract, one can see a convergence of the themes of Faust and Mephistopheles. Perception is interpreted as a respiratory problem. The narration is structured in such a way as to restrain the activity of themes associated with the image of the “fist” (Faust), transcending them with one meaning: creativity as the natural state of man. The search for the ultimate universal representation of the “poetic person” serves as the original meaning for the shape of events acquired in the novel. The mode of being that defines the poet possesses no categories of gender.
Pushkin’s “The Gypsies”: on a plot precedent in the stories of M. Gorky and I. A. Bunin
Authors:   Moscow Pedagogical State University, Uryupin Igor S.
Published: June 2023

The paper considers the moral, philosophical, ethical, and aesthetic potential of Pushkin’s poem “The Gypsies” in the vast historical, cultural, and literary context. This potential served as the ideological, semantic, and artistic-eidetic source of all subsequent “gypsy texts” of Russian literature reinterpreting the motifs, images, narratives, mythologemes, and archetypes stemming from the romantic story of the tragic love of Aleko and Zemfira. The focus is on the transformation poetics of the plot under study and its motif-image structure in the prose of the early 20th century. Following the methodological principles of cognitive literary criticism, the phenomenon of the “gypsy semiosphere” is studied in the stories of M. Gorky, “Makar Chudra,” and I. A. Bunin, “Bonfire,” at different levels of textual creation using historical-genetic, structural-semantic, systemic, and holistic research methods. The study has revealed a system of concepts and narrative schemes coming from “The Gypsies” and having a constant character enriched by the life and historical experience of Russian writers of the Silver Age. The ethnographic exoticism of the gypsy world in Russian literature proved to actualize the exceptional feelings and spiritual intensity of the internal processes of human existence subject to the power of the “passions of the fatal.” The love theme in its gypsy national-cultural nuance acquires a stereotypical character in the literature of the late 19th early 20th centuries. The image of the bonfire as a semiotic marker is analyzed through the artistic creation of the precedent “burning heart” plot by M. Gorky and I. A. Bunin.
“Special Path” of Siberian literature? (Experience in the reconstruction of historiosophical and literary critical sources of Siberian regionalism)
Authors:   Krasnoyarsk State Pedagogical University named after V. P. Astafiev, Gorbenko Alexander Yu.
Published: June 2023

An attempt is presented to reconstruct the historiosophical and literary-critical sources of Grigory Potanin’s article “A novel and a story in Siberia.” This article is key to the literary criticism of the “senior” regionalists. Consideration is given to two phenomena: 1) the Russian literature of the 19th century, regarded as “incorrect” as it was forced to evolve rapidly due to the lagging in its development (the consequence of the forced modernization of Russia), and 2) Western European literature, regarded “normal” and supplying the Russian literature with forms seen as models. These two phenomena were reproduced several decades later on a more local scale though less consistently: 1) Russian literature, having become “normative” for the Russian reader by the 1870s, and 2) the literature of Siberia lagging in its development compared to Russian literature. The leaders of Siberian regionalism would speak about the “specialness” of Siberia when comparing it both with Russia and Europe, with this “specialness” requiring a special representation. Considering criticism as an institution that “supervises” literature, Potanin, as his associate and friend Yadrintsev, suggested a radical thesis about the absence of literature in Siberia in his article. At the same time, relying on Karamzin’s article “Why are there few author talents in Russia?” and the first “Philosophical Letter” by Chaadaev, Potanin joins the discourse of the “shortage” of literature generated by several Russian critics of the first third of the 19th century. Potanin’s thought follows the paradigm formed in literary criticism and historiosophical discourse of this period.
Humanistic tendencies in the artistic and aesthetic system of Z. N. Gippius in her Petersburg Diaries of 1914–1919
Authors:   Yanka Kupala State University of Grodno, Shumskaya Lilya M. , Biliutenka Elena I. ,   Yanka Kupala State University of Grodno, Komarova Iryna K. ,   BIP-University of Law and Socio-informational Technologies, Grodno Branch
Published: June 2023

The Petersburg diaries (“Blue Book,”, “Black Notebooks,” “Black Book,” and “Gray Notepad”) document the attitude of Z. N. Gippius to the events related to the historical upheavals in Russia in the early 20th century. Searching for new ideas about personal freedom and choice in the epoch of historical cataclysms, the writer asserts the principles of new spirituality allowing one withstand the great upheavals of the era and achieve true freedom, found in God as a guarantor of the harmonious personality development. This study has established that the writer solves the problems suggested in the diaries by comprehending the fate of Russia during the First World War and the February and October revolutions of 1917 and searching for new humanistic ideals. She condemns the destructive nature of the revolution that causes the loss of moral ideals. Of particular relevance to the writer is the assertion of a specific, effective and practical humanism that takes into account the moral component of human life, approves the moral way of life, and combines practical actions with a focus on the individual as the ultimate goal. For Gippius, the ideal is embodied in the Russian intelligentsia with humanistic ability to sympathy, compassion, sacrifice, and sanctity and potential to withstand the political cataclysms of Russia. The aesthetic findings of Gippius in her Petersburg diaries embrace the inclusion of various associative chains into the forms of auto-documentary literature, enrichment of particular historical images with universal symbols, and synthesis of lyrical self-expression and an epic worldview.
On creating a register of information about evaluation reports
Authors:   Nizhny Novgorod State University of Architecture and Civil Engineering, Pylaeva Alena V. , Kol’chenko Olga V. ,   Gruppa Kompleksnykh Resheniy Ltd
Published: June 2023

The article examines the bill developed by the Ministry of Economic Development of the Russian Federation, which provides for the creation of a unified register of information contained in the reports on the assessment of objects of assessment (Register). The requirements of the current legislation for the information openness of the process of assessing objects of assessment are analyzed. The article also provides the names and details of the current legal acts governing the disclosure of information about assessment reports. The authors note that at present there are three types of information resources that must include the above data: (1) the Unified Federal Register of Information on the Facts of the Activities of Legal Entities and the Unified Federal Register of Bankruptcy Information included in it; (2) the data fund of the state cadastral valuation; (3) official websites of self-regulatory organizations of appraisers on the Internet. The negative aspects of the lack of a single resource for information on reports compiled on the basis of the results of determining the value of appraisal objects are indicated, and the prepared draft law is aimed at eliminating them. The authors structure the data to be included in the Register according to the document under consideration, according to the following parameters: type of information; cases of mandatory entry into the Register, the availability of publicly available information in the context of their types; persons and organizations submitting information, in the context of their types. In addition, the objectives of the introduction of the Register, contained in the explanatory note to the draft law, are analyzed. The analysis makes it possible to conclude that the Register, if the bill under consideration is adopted, will be able to perform the functions entrusted to it only partially. Information on the market value of appraisal objects entered in the Register (if it is formed) can be used as initial data for determining the cadastral value of land plots and their improvements. The article examines the degree of possibility of the Register’s application in the framework of the state cadastral valuation of real estate. The authors make a number of proposals to improve the usefulness of the Register for determining the cadastral value of land plots, buildings, structures, construction in progress, premises, parking spaces. They recommend to use a cadastral number as a unique single identifier in the Register, in the case when the object of assessment is a real estate object. Another reasonable proposal is to organize a structured storage of data in the Register (if it is created) in order to perform an information and analytical function on the objects of assessment, analogue objects, various indicators that affect the market value of land plots and their improvements, from assessment reports.
Communication aspects of supporting national projects in Russia
Authors:   National Research University Higher School of Economics, Bolshakova Ksenia Yu.
Published: June 2023

In the article, the author analyzes the developed communication approaches in the implementation of national projects and draws conclusions about the importance of preserving and activating existing measures in times of crises that Russia is experiencing in new socio-political and economic realities (sanctions, special military operation, general isolation). The article focuses on the activities of the ANO National Priorities created by the Government of Russia and its approaches to the formation of a national idea as one of the tools for implementing state information policy and overcoming communication gaps between society and the state. The relevance of the issue under consideration is due to the need for a better understanding of the possible format of interaction between the state and the population, changes in approaches to public administration taking into account the new realities of the information society. The author puts forward the hypothesis of the study, which consist in the assumption that the activation of the activities and expansion of the range of communication tools of the ANO National Priorities, including the formation of a single brand, active promotion of events, projects related to the implementation of national projects and government activities in new conditions, contributes to overcoming the communication gap. This, in turn, contributes to the formation of a stable positive relationship between the state and society, entails the preservation and increase of public knowledge about government initiatives, and an increase in public confidence in the state. The aim of the study is to identify the dynamics of changes (extensions) of the communication aspects of the support of national projects in Russia and the selected methods of information delivery used by the ANO National Priorities. In addition, the identification of their influence on feedback from the population, overcoming the communication gap, which, according to the author, has worsened recently, and, as a result, on increasing the confidence of the authorities. The aim and the hypothesis contributed to the disclosure of the topic of the article and the solution of the following research objectives: (1) identification of the role of the ANO National Priorities as the main communication tool for the accumulation of resources, data on national projects and one of the main tools for the implementation of state information policy and the formation of a national idea; (2) analysis of the communication and marketing tools of information delivery used by the ANO National Priorities; (3) demonstration of the role of national projects as an ideological component in overcoming the existing communication gap in society.
Electronics industry: Prospects for development and for Russia’s cooperation with friendly countries
Authors:   Peoples’ Friendship University of Russia, Yampolskaya Diana O.
Published: June 2023

After the events of early 2022, import substitution issues are being actively discussed in the economic sphere. One of the most problematic areas is microelectronics – the production of semiconductors and chips for a variety of parts and devices. The Government of the Russian Federation is developing various options for increasing the production of electronic components. However, there are a large number of problems associated with the fact that no country is completely selfsufficient in the production of these goods. Finding partners is essential. In this article, the problem of production is considered through the prism of expert assessments of the situation in the Russian Federation, as well as in the EAEU countries, China, and India – countries considered friendly for our country, and cooperation with them is quite possible. But these countries are also not entirely self-sufficient in producing the most in-demand range of semiconductor products in the right sizes. The EAEU countries, namely Belarus and Armenia, do not have the necessary advanced technologies; China is under partial sanctions that hinder its development. India is also not a leader in this direction, although it is actively looking for ways to develop. It is necessary to develop cooperation between the countries in the electronics industry as the United States will try to prevent the development of electronics, both in Russia and among its partners.
Two sides of the householder’s self-governance: Self-knowledge and self-management. Introduction
Authors:   Siberian State Medical University, Zemtsov Anatoliy A.
Published: June 2023

The article discusses the theoretical foundations of self-governance, a person’s rule over oneself. The specificity of the author’s view of the issue is a holistic approach to the individual, the allocation of four main components in the individual’s structure. The production, professional component among the four is special and is aimed at generating income for a holistic life. Self-governance has two sides – self-knowledge and self-management. There are three levels of selfgovernance; only one of them is associated with the human consciousness, which explains the predominance of indirect – catchwords, storytelling, trial and error, biographical, scenario – management methods in it. The application of the proposed model of self-governance for the “mastery of life” style is substantiated.
Standard of living in some regions of Siberia: Interrelation with various factors
Authors:   International Business Consulting Group LLC, Mitroshin Igor V.
Published: June 2023

Indicators of the standard of living of the population reflect the degree of the economic development of the region, its production and economic potential, and attractiveness for the population. Therefore, in our opinion, there is a dependence of the demographic situation on the quality of life of the population of the region, as well as on the main financial and economic indicators, such as the gross regional product. An analysis of the relationship of all these indicators helps identify the problems of the economic development of the region and ways to solve them. The study analyzes the impact of indicators of the standard of living, such as the average monthly wage, as well as the ratio of the average monthly wage to the subsistence minimum, on changes in the population of the region. The mutual influence of the gross regional product and the living standards of the population is considered. The production of gross regional product per capita was chosen as the main indicator of the assessment. The analysis includes data from two regions of Western Siberia – Novosibirsk and Tomsk Oblasts, and two regions of Eastern Siberia – Irkutsk Oblast and Zabaykalsky Krai for the period 2000–2021. The comparison shows that the factors of the standard of living of the population and the production of the gross regional product have an impact on the demographic situation in the region only in their combination. The influence of each individual factor, both on the population and on the standard of living, as a rule, is insignificant. People’s expectations are also of particular importance, that is, the population is growing, there is migration to the region if the region has high rates of growth in the standard of living and economic development, despite the relatively low current rates. The results of the study can be used for further broader analysis and forecasting of indicators of the standard of living of the population in the regions and in Russia in general.
The theory of deferred taxation: Evidence of its applicability and conceptual framework
Authors:   Kuban State University, Aksent’ev Andrei A. ,   Perspektiva LLC
Published: June 2023

The paper attempts to disclose the conceptual foundations of the theory of deferred taxation, based on the provisions of the concepts of temporary and term (temporal) differences secured by modern accounting standards. The study summarizes the key aspects of the corporate tax distribution procedure (intra-period and inter-period) and tax effects (pass-through, partial, and full). The methods of accounting for deferred taxes: liability, deferral, and net taxation are characterized. The financial nature of deferred taxes is described, including the legal side in terms of their correlation with the categories of assets and liabilities. The criteria for recognition of tax effects depending on the concept of deferred tax accounting are given. The applicability of deferred taxation theory is substantiated using formalization techniques: the derived equations explain the importance of deferred tax accounting, which corrects the financial assessment of assets and liabilities in the direction of the accurate reflection of economic reality. Other unresolved controversial issues in the field of research are considered, and the author’s position in determining the directions of their solutions is offered. The results of the work are useful for further theoretical elaboration, the aim of which is the development of accounting methodology, including the issue of tax effects accounting. Many provisions can be used in the preparation of national accounting standards. Perspective directions of research are the disclosure of economic content of deferred taxes, the conduct of empirical tests with the specified object of accounting observation in order to identify statistical dependencies, which can be used in practical activities, for example, to assess the tax behavior of companies.
A Critical Review on Corrosion and Fouling of Water in Water Distribution Networks and Their Control
Authors: Anshar Andi Muhammad , Musa Bulkis , Ayaz Muhammad , Kasim Syahruddin , Raya Indah , Ramírez-Coronel Andrés Alexis , Chowdhury Shakhawat , Zabibah Rahman S. , Romero-Parra Rosario Mireya , Barboza-Arenas Luis Andres , Mustafa Yasser Fakri , Al-Khafaji Ali Hussein Demin
Published: June 2023

Corrosion and scaling are among the problems that may arise when storing water in tanks. Several factors affect the corrosion and scaling of water, which include pH, temperature, alkalinity, Ca2+ hardness, TDS, concentrations of Cl–, SO42–, CO32–, and HCO3–. Also, several indices can be measured using these properties such as the Langelier saturation index, Ryznar index, Aggressive index, Larson, Scold index, water quality index, and Puckorius index. These indicators determine the degree of corrosiveness and sedimentation of water. The purpose of this review article was to study the impact of various factors on the corrosiveness and sedimentation of water. To this end, different sources of water in different countries were studied and the impact of physical and chemical parameters on their corrosiveness was investigated. Also, the reaction mechanism of water corrosion inside the pipe was studied. Finally, practical and constructive suggestions were presented to solve the problems of corrosion and sedimentation of desalination water.
Effect of Ozone on Oxygen Transport and Pro-Oxidant- Antioxidant Balance of Red Blood Cell Suspension
Authors: Zinchuk Victor , Biletskaya Elena
Published: June 2023

Introduction: Ozone affects blood oxygen transport and the pro-oxidant-antioxidant balance. However, the role of blood formed elements and gas transmitters in these processes still remains unclear. The aim of the present study was to investigate the effect of ozone on oxygen transport and the pro-oxidant-antioxidant balance in a red cell suspension. Methods: The red cell suspension was incubated with ozone at a concentration of 6 mg/l and substances affecting the synthesis of gas transmitters (nitroglycerin, sodium hydrosulfide). Parameters of blood oxygen transport and pro-oxidant-antioxidant balance were determined. Results: The effect of ozone on blood oxygen transport was found which was manifested in an increase in oxygen partial pressure and the degree of oxygenation. The index of hemoglobin –oxygen affinity p50 actual was raised and a shift of the oxyhemoglobin dissociation curve rightwards was noticed. The addition of the gas transmitter donor, nitric oxide, enhanced the effect of this gas on the parameters of oxygen transport in the erythrocyte suspension Conclusion: We found that ozone induced a change in oxygen-binding properties of the erythrocyte suspension which is a mechanism of action of the above gas on the adaptive processes in the body realized directly at the level of erythrocytes.
Oceans’ surface pH-value as an example of a reversible natural response to an anthropogenic perturbation
Authors: Hans-Rolf Dübal , Fritz Vahrenholt
Published: June 2023

The anthropogenic emission of carbon dioxide (CO2) has influenced the pH values of the oceans’ surface. Observations show that for several decades, the surface pH value is declining with a simultaneously rising CO2 concentration. It is an important question to understand to what extent this process is reversible. Hence, in this study, the atmospheric carbon dioxide (CO2) partial pressure from 1850 to 2020 is derived from the chemical composition of the seawater, the mass action law, Henry’s law, and published literature data on the relevant equilibrium constants. A single exponential relaxation or equilibration time τ = 52 ± 10 years (or half-time of 36 ± 7 years) accounts for the anthropogenic perturbation due to emissions. The model is based on reversible mechanisms and simultaneously represents the atmospheric CO2 volume fraction with a standard deviation of 7 ppm and the oceans’ surface pH values. Projections until 2100 for various emissions include the possibility of recovery within decades.
Quick and dirty sequencing microbial genome extraction v1 v1
Authors: won Lim Sung
Published: June 2023

Quick and dirty microbial genome extraction protocol using Edwards buffer. I've been using this method for in-lab Archaeal evolution study for the last four years or so and it's been working fantastically well, especially for short read sequencing. Certain microbes (such as Deinococcus) can be difficult to process properly using just this protocol - standard caveats and fixes tend to improve the output, such as adding initial lysozyme incubation step in the very beginning, sometimes combined with a freeze-thaw cycle for especially difficult samples (I'll update and upload a separate version of this protocol for difficult microbes in the future). This particular protocol is aimed at getting as much intact, long-read capable DNA out from a microbe as cheaply as possible, as shown in the included gel picture. Originally written up for my lab note at https://naturepoker.wordpress.com/2023/02/26/halobacteria-mutant-sequencing-3-years-in/ Ideation and initial testing performed with Sebastian S. Cocioba at Binomica Labs for ONT Deinococcus radiophilus genome sequencing project, using RAD004 rapid sequencing kit. https://www.ncbi.nlm.nih.gov/assembly/GCF_020889625.1
Induced Pluripotent Stem Cell Reagents v1
Authors: not provided wmallory
Published: June 2023

reagents used to maintain our IPSC
Tilting at 5G Towers: Rethinking Infrastructural Transition in 2020
Authors: Sharp Rory
Published: June 2023

5G has the potential to expand the horizons of digital inclusion by providing higher speeds, lower latency, and support for more devices on a given network. However, mis‐ and disinformation about 5G has proliferated in recent years and stands to be a persistent barrier to the adoption of this generation of wireless technologies. After rumours linking 5G to Covid‐19 emerged in the wake of the pandemic, isolated actors attempted to disrupt infrastructure with a perceived connection to 5G. Media coverage of these incidents inadvertently spread such claims, engendering lasting uncertainty about 5G. Infrastructure scholars have long held to the maxim that “the normally invisible quality of working infrastructure becomes visible when it breaks” (Star, 1999, p. 482), but efforts to interpret the uptake of mis‐ and disinformation have struggled to define the technical difference 5G makes and describe diffused acts of anti‐5G sentiment that exploited its slippery symbolic associations. What broke to make 5G so visible? This article reassesses interference with infrastructure through the lens of a literary metaphor derived from Miguel de Cervantes’ epic novel Don Quixote. Using the Don’s famed joust with windmills, I examine what efforts to disrupt the development of 5G in 2020 can tell us about infrastructural transition. With reference to Quixote’s tilt, I contend that the disruptions of 2020 illustrate conflicting imperatives of inclusion and exclusion underlying neoliberal schemes of telecommunication development.
Social Determinants, Urban Planning, and Covid-19 Response: Evidence From Quito, Ecuador
Authors: Herrero-Olarte Susana , Díaz-Márquez Angela
Published: June 2023

Covid-19 has put all urban planning systems around the world to the test. Cities’ design and how these are managed are being observed, analyzed, and even questioned from the perspective of the pandemic. Density and poverty have been two fundamental aspects to manage in the pandemic scenario in cities of the Global South, which face this challenge along with other pre-pandemic planning problems. In the city of Quito, Ecuador, the response to the pandemic has been coordinated through regulations issued by the emergency operations center at the national level, and the information (number of cases) has been recorded per parish. The objective of this research is to determine if there is a relationship between Covid-19, poverty, and population density at the parish level for the canton of Quito. The results have shown that there is no correlation. What they did show is that due both to the difficulties of responding to the pandemic and the city’s planning structure, another type of characterization, or characterizations, of the territory (for example, by scenarios or by situations) is needed, which can respond to the needs of the most vulnerable groups. Another observable result was that the gap between urban planning and management instruments and the complexity of territorial needs contributes to the polarization of local government approaches, which compromises urban planning with minimum continuity and coherence.
New possibilities of cell and shock wave therapy in erectile function recovery in patients after radical prostatectomy: a review
Authors: Epifanova M. V. , Kostin A. A. , Gameeva E. V. , Gritskevich A. A. , Artemenko S. A. , Epifanov A. A.
Published: June 2023

For the first time in 2021, prostate cancer took 1st place among other oncological diseases in Western countries. Radical prostatectomy is still the method of choice among the prostate cancer radical therapy. An important unresolved problem remains the rehabilitation, since the overwhelming number of patients in the postoperative period develop sexual dysfunction, urination disorders, which significantly reduces the quality of life. Thus, this condition actualizes the search and development of new approaches to the therapy of erectile function after radical prostatectomy. This literature review presents the results of a literary search of Russian and international databases on the erectile function recovery after radical prostatectomy using platelet rich plasma and extracorporeal shock wave therapy.
Immunohistochemical basing of the pathogenesis equality of varicose vein transformation in varicocele and varicose veins of the lower extremities
Authors: Severgina L. O. , Studennikova V. V. , Rapoport L. M. , Korovin I. A. , Korolev D. O.
Published: June 2023

Background. Varicocele as well as varicose veins of the lower extremities are quite widespread. To date, the mechanisms of variceal transformation remain not completely clear.

Aim. To study the immunohistochemical profile in order to substantiate the common pathogenesis of varicose veins transformation in varicocele and varicose veins of the lower limbs; to confirm the key role of undifferentiated connective tissue dysplasia syndrome in the development of these diseases.

Materials and methods. Vein wall fragments from 24 male patients aged 6–35 years old divided into the corresponding groups: group 1–12 patients with varicocele, group 2–12 patients with varicose veins of the lower limbs. Control group – 5 practically healthy men (age 16–32 years). Immunohistochemical study was performed with monoclonal antibodies to collagen types III, IV, α-SMA, fibronectin, laminin, MMP-2 and MMP-9, TGF-β1.

Results and discussion. Histological and immunohistochemical studies of vein wall biopsy specimens in both groups revealed similar morphological changes, different from the control group. When assessing the expression level of α-SMA in both study groups, there was marked expression in the bundles of hypertrophic smooth muscle cells (in the zone of wall thickening where fibrosis was minimal) and weak expression in the bundles of smooth muscle cells “enmeshed” in connective tissue sleeves. Collagen type III showed weak expression in the subintimal zone and between the bundles of superficially located smooth muscle cells in both study groups. Expression of type IV collagen was detected in the areas of wall thickening and hypertrophy of smooth muscle cells. In both groups there was a pronounced expression of fibronectin in the most altered sections of the vein walls, especially in the middle layer, around the bundles of smooth muscle cells. There was marked expression of MMP-2 in all layers of the wall, and overexpression of MMP-9 in the areas of wall thinning (in the subintimal zone and muscular layer). TGF-β1 overexpression was also detected in vein biopsy specimens from both groups, predominantly in areas of thinning and pronounced intermuscular fibrosis.

Conclusion. Taking into account the similarity of immunohistochemical manifestations in the vein walls in varicocele and varicose veins of the lower limbs we can speak about the common morphogenetic mechanisms of their remodeling. Thus, we consider it possible to combine various forms of varicosity into a single disease – varicose vein disease.
Detection of Ureaplasma species in males with reproductive problems in marriage
Authors: Savzikhanov R. T. , Muskhadzhiev A. A. , Katibov M. I.
Published: June 2023

The article provides information on the impact of Ureaplasma infection on the reproductive function of men. It was found that the prevalence of the microorganism in men with reproductive pathology was 55 %. The presence of ureaplasmas in clinically healthy men, the relationship with the presence of inflammatory diseases of the urinary system, male infertility and adverse pregnancy outcomes were determined. It has been established that ureaplasmas make the greatest contribution to the development of miscarriage and adverse pregnancy outcomes.
From Chariot Warfare to Naval Conquests: Military Scenes on the Walls of New Kingdom Temples and Tombs
Authors:   Taras Shevchenko national University of Kyiv, Bondarenko Nataliia
Published: June 2023

This article examines the military scenes depicted on the walls of New Kingdom temples and tombs, specifically those belonging to the pharaohs Thutmose III, female pharaoh Hatshepsut, Tutankhamun, Ramses III, and Seti I. The author examines the artistic features, composition, and symbolism of these images, as well as their historical and political significance. Through an analysis of these military scenes, the article seeks to shed light on the political, social, and religious functions of the pharaohs’ military campaigns, as well as their impact on ancient Egyptian society. These scenes often depict military campaigns, battles, and triumphs, as well as offerings made to the gods in gratitude for victory. Some scenes depicted the pharaoh defeating foreign enemies in order to protect Egypt and maintain Ma’at, the ancient Egyptian concept of order and balance in the universe. One example of such scenes can be found in the Temple of Karnak, which features a relief showing King Seti I leading a procession of soldiers in tribute to the gods. Another example is the depiction of the Battle of Kadesh, fought between the Egyptians and the Hittites, which can be seen in the Temple of Abu Simbel. The study draws on a range of primary and secondary sources, including archaeological data, textual evidence, and art historical analysis, to provide a comprehensive examination of these important historical artefacts. Ultimately, the article argues that the military scenes found in New Kingdom temples and tombs offer valuable insights into the ways in which the pharaohs projected their power and authority, and how they sought to legitimize their rule through both military might and religious symbolism. Overall, the military scenes on the walls of temples of the era of the New Kingdom offer a fascinating glimpse into the culture and values of ancient Egypt.
Scribo Comentiolus as Ambassador to the Avars in 583
Authors:   Ivan Franko National University of Lviv, Ukraine, Lahodych Volodymyr
Published: June 2023

A feature of the career development of the military nobility of the Eastern Roman Empire in the last third of the sixth century was participation in diplomatic missions. Acting as envoys of the Justinian emperors, Roman generals and soldiers represented the interests of Constantinople before the barbarian rulers. The peculiar turnover of personnel was facilitated by the peculiarities of Roman diplomacy aimed at political neutralisation of neighbours, as well as the personal desire of autocrats to test their protégés in the foreign policy arena. This was compounded by the lack of experienced diplomats and generals in the Roman Empire. As a result, a number of soldiers and generals of the Empire who enjoyed the personal trust of emperors often acted as envoys in negotiations with the rulers of barbarian political units. The scribon Comentiolus, who was involved in the Roman embassy sent in 583 to the Avar Khagan Bayan I (562–602), was no exception to this context. Having been the personal bodyguard of Emperor Maurice (582–602) at the beginning of his reign, Comentiolus later held the positions of dux of Mesia, military master of the East, and stratigos of Thrace. Comentiolus career growth was mainly due to his talent as a commander. Nevertheless, at the beginning of his service to Maurice, scribo was sent by Mauritius as an ambassador to the headquarters of the Avar Khan to end the war with Constantinople that began in 582. Despite the formal heading of the mission to Anchialus by Senator Elpidius, scribo actually defended the interests of the Empire. Bayan’s provocations during the negotiations with the Romans provoked Commentius to make a patriotic speech in which he accused the Avars of disrespecting Constantinople. Ultimately, Comentiolus’ actions as ambassador were the direct cause of the failure of the diplomatic mission and the continuation of the war.
Weight Systems in Italy in the VI – the First Half of the XIX Century
Authors:   Taras Shevchenko national University of Kyiv, Zubko Andrii
Published: June 2023

Medieval Italy, which was formed after the fall of the Western Roman Empire at the end of the V century, completely inherited its material and spiritual culture. This does not apply to the state imperial traditions of Ancient Rome. It turned out that during the entire period of the Middle Ages and partly of the New Age – from the end of the V to the second half of the XIX century, Italy was not a single state. At this time, three main regions – Northern, Central and Southern Italy – were gradually formed here. Each region included several historically interconnected regions. In the territory of these regions, there were cities – republics and separate feudal estates. Each region preserved its distinctive features throughout the Middle Ages. Some of these differences have survived even in modern Italy. They arose from the peculiarities of the geographical environment, as well as the political and economic conditions that developed over a long period of time in each of the three regions of Italy. The single system of measures, including weight, which existed in the Roman Empire, in the conditions of political decentralization of Italy, was gradually, over the centuries, replaced by local measures. The basis of most of the newly created systems of weight measures in Italy was the ancient Roman system of weight measures. However, the development of production, domestic and foreign trade caused a constant transformation of the structure of the systems of weight measures, the mass of their units. Gradually, new systems of weight measures were formed in Italy. The structure of the systems of weight measures in Italy had certain common features, but the mass of their units differed among themselves in almost all cases. The weight systems of Italy during the Middle Ages were influenced by the dependence of the Italian lands at certain times on the empire of Charlemagne, the Holy Roman Empire of the German nation, and the Austro-Hungarian Empire. As a result, in some areas of Northern and Central Italy, along with the local systems of weight measures, the following measures began to be used: Carolingian silver and troy weight systems, the German Cologne system of weight measures, Austro-Hungarian weight measures. The long-term existence of the leading Italian city-states – the republics of Venice and Genoa, the Duchies of Milan and Tuscany, the Papal State, the Kingdom of the Two Sicilies, etc. was a consequence of the use of constantly operating systems of measures and weights in the territory of Italy during the entire period of the Middle Ages.
Contemporary Popular Culture Through the Lens of Historical and Philosophical Vision
Authors:   Taras Shevchenko national University of Kyiv, Pilkevych Andrii
Published: June 2023

The article provides an analysis of contemporary popular culture and its influence on society. Focusing on current trends and aspects of popular culture, the article explores key factors that shape this culture and define its place in the modern world. Contemporary popular culture has gained recognition as a social phenomenon, exerting significant impact on various aspects of society. Its influence is manifested in the creation and dissemination of cultural artifacts that actively engage with societal stereotypes, values, and perspectives. These artifacts can stimulate discussions, alter consciousness, and contribute to social change. Through technological communication tools and global media, «cultural products» such as music, literature, films, the video game industry, fashion, are disseminated worldwide, facilitating the exchange of ideas, cultural convergence, and the emergence of global trends. With the aid of technological communication means, integral narratives spread rapidly across the globe, resulting in cultural hybridity and the development of shared cultural experiences. However, in the process of globalization, there are inherent risks of cultural homogenization and loss of cultural diversity. Popular culture often becomes subservient to global commercial interests, yet it also becomes an object of interpretation and resistance. Active consumers reproduce, transform, and utilize «cultural products» based on their unique contexts, values, and needs. This process presents opportunities for critical analysis, alternative interpretations, and the formation of new cultural norms. Integral trends become essential means of expression, recognition, and the search for personal and collective identities. This process can be conducive, but it can also give rise to conflicts and contradictions, particularly within the context of cultural diversity and globalization. Social media platforms not only facilitate the dissemination of cultural trends but also provide a platform for self-expression and interaction between content producers and consumers. This is complemented by augmented reality, artificial intelligence, blockchain, making contemporary creativity and consumption processes a unique phenomenon that continually unlocks new possibilities.
Clinical case of psoriasis in an HIV-positive patient
Authors: Kleymenova Valeriya E. , Krinitsyna Yulia M. , Pakhomova Vera V.
Published: June 2023

Modern ideas about psoriasis are becoming wider, while the incidence of this dermatosis is increasing every year. Psoriasis does not seem to be just a skin pathological process, since the basis of this disease is the development of chronic systemic immune inflammation resulting from the launch of a complex cascade of immune reactions with impaired activity of T-lymphocytes and the production of various pro-inflammatory cytokines and chemokines.
The course of psoriatic disease has its own characteristics in a patient with human immunodeficiency virus. The peculiarities of the course of psoriasis in a patient with human immunodeficiency virus require a personalized approach in therapy.
This article describes a clinical case of psoriasis in a patient with newly diagnosed human immunodeficiency virus. The stages of the diagnostic search for HIV infection are described. To confirm the diagnosis of psoriasis, a pathohistological examination of a skin biopsy was performed, as well as additional laboratory and instrumental studies. The main features of the course of psoriatic disease in an HIV-positive patient are demonstrated: a combination of several clinical forms of the disease, severe severity, lack of necessary positive dynamics against the background of external and basic anti-inflammatory forms of therapy.
Features of clinical diagnosis of IgA-pemphigus in a patient with a long history of the disease
Authors: Sorokina Elena D. , Krinitsyna Yulia M. , Pakhomova Vera V.
Published: June 2023

Ige-dependent pemphigus is a rare autoimmune vesicular disease and is characterized by painful and itchy vesicular rashes on the skin. Ige-dependent pemphigus is one of the rarest forms of autoimmune bullous dermatoses.
The article describes the clinical case of patient T., aged 82 y.o., who applied to the Novosibirsk Regional Clinical Dermatovenerologic Dispensary with complaints of rashes on the skin of the trunk, limbs, periodically accompanied by itching. For the first time, rashes began to appear 20 years ago, more often in the summer. She was observed by a rheumatologist with a diagnosis of chronic vasculitis, during exacerbation, against the background of therapy with systemic glucocorticosteroids, the rashes regressed. During the last exacerbation after suffering a Novel coronavirus infection at the age of 82 y.о., patient turned to a dermatologist against the background of an injection of a solution with betamethasone, with partially regressed rashes, which made it difficult to establish a diagnosis. After 2 weeks, against the background of discontinuation of therapy, another exacerbation occurred, characterized by obvious clinical manifestations of neutrophilic bullous dermatosis in the form of flaccid pustulеs on the skin of the trunk, upper extremities, as well as serous-purulent crusts arranged in the form of rings and garlands. Based on the history, clinical features and laboratory studies, without the use of immunofluorescence, a provisional diagnosis of IgA-dependent pemphigus was made, systemic glucocorticoid therapy was prescribed with a long-term gradual withdrawal, with a positive effect.
At the intersection of health and aesthetics: Sechenov University held the anniversary conference “Rakhmanov readings”
Authors: Maximov Ivan S. , Yakovlev Alexey B.
Published: June 2023

On May 12, 2023, 40-th Rakhmanov readings were held in Moscow. The conference, which has long become traditional, has now become a major interdisciplinary and international forum bringing together representatives of not only therapeutic, but also aesthetic medical specialties.
The program of the anniversary conference "Rakhmanov readings 40 years" was rich: it covered new trends in dermatology and cosmetology; issues of diagnosis, treatment, prevention and rehabilitation of dermatoses. At the same time, the participants got acquainted and established interdisciplinary contacts.
In total, 11 sections, 10 symposiums, 1 quiz were held within the framework of the scientific and practical conference "Rakhmanov Readings"; 100 scientific reports on dermatovenerology and cosmetology were presented.
Checkpoint inhibitor-induced immune-related sarcoidosis-like reaction
Authors: Shakirov R. R. , Basin I. S. , Krashikhina T. V. , Tekeeva A. I. , Chernysheva E. S. , Lyadov K. V.
Published: June 2023

Immune checkpoint inhibitors are associated with a wide spectrum of immune-related adverse events (AE) of different severity. Immune-related sarcoidosis-like reactions are relatively rare but clinically important AEs. These abnormalities, due to the appearance of active pathological lymph nodes or nodules in other organs on radiographs, can be falsely interpreted as tumor progression or stabilization and thus affect treatment strategy, leading to unreasonably early therapy discontinuation or its unnecessary continuation. So far there were no convincing criteria for differentiation between sarcoidosis-like reaction and sarcoidosis, oncologist should be aware of this reaction and include it in the differential diagnosis in patient with suspected disease progression who are treated with immune checkpoint inhibitors.