bluuebunny/crossref_metadata_2025 huggingface dataset:
Perfect modulation between fully spin-polarized spin-singlet and -triplet Andreev entanglements in a narrow quantum spin Hall system
Authors: Liu Tingmin , Chen Fujun , Tao Y. C. , Huang Chuanshuai
Published: December 2020

We consider a quantum spin Hall (QSH) insulator strip touching on one s-wave superconductor sandwiched between two ferromagnetic insulators and study its scattering processes, tunneling conductance, and noise power by using an extended Bogoliubov-de Gennes scattering formalism. It is demonstrated that interedge coupling and noncollinear magnetizations allow for producing the usual and novel crossed Andreev reflections (ARs), respectively, and thus the corresponding spin-singlet and -triplet pairing entanglements. Moreover, by proper tuning of the band structures of the ferromagnetic layers, under the resonance bias voltage, not only perfect but also fully spin-polarized crossed AR at any magnetic orientational angle α is exhibited, which can be experimentally confirmed by the tunneling conductance and noise power. Particularly, the perfect and fully spin-polarized modulation between the spin-singlet and -triplet Andreev entanglements could be performed by α at certain energy values, which suggest that the setup can act as a topological superconducting spintronic device with such a manipulation function.
Elevated Plasma Concentrations of Syndecan-1 Do Not Correlate With Increased Capillary Leakage of 20% Albumin
Authors: Hahn Robert G. , Zdolsek Markus , Krizhanovskii Camilla , Ntika Stelia , Zdolsek Joachim
Published: December 2020

BACKGROUND:

Preclinical experiments show that an inflammatory reaction causes degradation of the endothelial glycocalyx layer and accelerated capillary leakage of albumin and fluid. The hypothesis in the present study was that elevated plasma concentrations of glycocalyx degradation products are associated with greater capillary leakage in humans.

METHODS:

This open clinical trial involved administration of an intravenous infusion of 20% albumin at 3 mL/kg over 30 minutes to 15 postburn patients who showed an activated inflammatory response. Blood samples and urine were collected for 300 minutes. The plasma concentrations of 2 biomarkers of glycocalyx degradation—syndecan-1 and heparan sulfate—were measured at 0, 60, and 300 minutes and compared to the capillary leakage of albumin and fluid obtained by mass balance calculations and population kinetic analysis.

RESULTS:

Patients were studied at 7 days (median) after a burn injury that covered 15% (maximum 48%) of the body surface area. The median plasma syndecan-1 concentration was 71 (25th–75th percentiles, 41–185) ng/mL. The 2 patients with highest values showed 2279 and 2395 ng/mL (normal 15 ng/mL). Heparan sulfate concentrations averaged 915 (673–1539) ng/mL. The infused amount of albumin was 57 (48–62) g, and 6.3 (5.1–7.7)% of that leaked from the plasma per hour.

Linear correlation analysis of the relationship between the 10logarithm of the mean syndecan-1 and the albumin leakage showed a slope coefficient of −1.3 (95% confidence interval [CI], −3.6 to 1.0) and a correlation coefficient of −0.33 (P = .24). The kinetic analysis revealed that syndecan-1 served as a statistically significant covariate to the albumin leakage, but the relationship was inverse (power exponent −0.78, 95% CI, −1.50 to −0.05; P < .02). Heparan sulfate levels did not correlate with the capillary leakage of albumin or fluid in any of the analyses.

CONCLUSIONS:

A raised plasma concentration of syndecan-1 alone cannot be extrapolated to indicate increased capillary leakage of albumin and fluid.
Antibacterial activity in secondary metabolite extracts of heterotrophic bacteria against Vibrio alginolyticus, Aeromonas hydrophila, and Pseudomonas aeruginosa
Authors: Setiaji Jarod , Feliatra Feli , Teruna Hilwan Yuda , Lukistyowati Iesje , Suharman Indra , Muchlisin Zainal Abidin , Johan Teuku Iskandar
Published: December 2020

Background: Disease causing bacteria such as Vibrio alginolyticus, Aeromonas hydrophila, and Pseudomonas aeruginosa present a problem for fish farming. Treatment to remove them are generally carried out using antibiotics which have side effects on fish, the environment and humans. However, the use of antibacterial compounds derived from heterotrophic bacteria serve as a good alternative for antibiotics. Therefore, this study aimed to explore antibacterial activity in the secondary metabolite extracts of heterotrophic bacteria against Vibrio alginolyticus, Aeromonas hydrophila, and Pseudomonas aeruginosa.

Methods: Heterotrophic bacteria namely Bacillus sp. JS04 MT102913.1, Bacillus toyonensis JS08 MT102920.1, Bacillus cereus JS10 MT102922.1, Bacillus sp. JS11 MT102923.1, Pseudoalteromonas sp. JS19 MT102924.1, Bacillus cereus JS22 MT102926.1, and Bacillus sp. strain JS25 MT102927.1 were used in this study. The sequences of these bacteria have been deposited and are available from NCBI GenBank. Each heterotrophic bacterium was cultured on 6L nutrient broth for 8 days, and extracts produced using ethyl acetate to obtain their secondary metabolites. These extracts were tested for their phytochemical contents using FT-IR and also tested for their inhibitory property in pathogenic bacteria by agar diffusion method.

Results: Phytochemical test results showed that the seven heterotrophic bacterial isolates produced terpenoid compounds. Based on the inhibitory test, the secondary metabolite extracts from Bacillus sp strain JS04 had the highest inhibitory effect on the growth of pathogenic bacteria namely, V. alginolyticus (17.5 mm), A. hydrophila (16.8 mm), and P. aeruginosa (17.3 mm).

Conclusion: It was concluded that the secondary metabolite extracts of heterotrophic bacteria inhibit the growth of V. alginolyticus, A. hydrophila, and P. aeruginosa.
Analysis of instagram profiles found through inscriptions on the walls of the In – Patient Adolescent Psychiatry Unit at the University Hospital in Kraków, Poland
Authors: Urbanek-Matusiak Katarzyna , Katerla Aneta , Szczecina Agata , Pilecki Maciej
Published: December 2020

Aim of the study

Adolescents are increasingly active in social media: 72% use Instagram while as many as a quarter suffer from at least one mental disorder, Internet users among them. A number of studies confirming the mutual influence of social media and mental health have been conducted but there is a shortage of data on the Internet activity of people suffering from mental disorders. This study aims at extending the existing knowledge by analyzing Instagram accounts of adolescent psychiatric in-patients.

Subject or material and methods

We analyzed the contents of Instagram accounts, links to 36 of which were hidden in graffiti drawn by patients on the walls of an inpatient adolescent psychiatric ward. After excluding inactive and nonexistent accounts, 21 addresses were analyzed with respect to the number and content of published posts and comments left under them.

Results

90% of the accounts belonged to girls. 52% revealed the owner’s identity. The posts were mainly depressive, which correlated with the psychopathology of the patients. The comments differed in number and in character depending on the content of the post: replies to posts related to body image were mainly supportive, while comments on posts related to self-harm mainly expressed sympathy.

Discussion

Most of the analyzed Instagram posts are related to the typical psychopathology of the patients hospitalized on our ward. In addition, it is also similar to negative effects that social media may have on mental health.

Conclusions

The association found in the study show that conducting further research on social media use by psychiatric patients may be clinically important.
5G network slicing with QKD and quantum-safe security
Authors: Wright Paul , White Catherine , Parker Ryan C. , Pegon Jean-Sébastien , Menchetti Marco , Pearse Joseph , Bahrami Arash , Moroz Anastasia , Wonfor Adrian , Penty Richard V. , Spiller Timothy P. , Lord Andrew
Published: December 2020

We demonstrate how the 5G network slicing model can be enhanced to address data security requirements. In this work, we demonstrate two different slice configurations, with different encryption requirements, representing two diverse use-cases for 5G networking, namely, an enterprise application hosted at a metro network site and a content delivery network. We create a modified software-defined networking (SDN) orchestrator that calculates and provisions network slices according to the requirements, including encryption backed by quantum key distribution (QKD) and other methods. Slices are automatically provisioned by SDN orchestration of network resources, allowing selection of encrypted links as appropriate, including those that use encryption with standard Diffie–Hellman key exchange, QKD, or quantum-resistant algorithms, as well as no encryption at all. We show that the setup and teardown times of the network slices take approximately 1–2 min, which is at least an order of magnitude improvement over manually provisioning a link today.
Low loss hollow-core antiresonant fiber with nested supporting rings
Authors: Zhu Yunhao , Song Ningfang , Gao Fuyu , Xu Xiaobin
Published: December 2020

A hollow-core antiresonant fiber (HC-ARF) with nested supporting rings (NSRs) is designed and simulated. The HC-ARF with NSRs has advantages and benefits of low loss, large bandwidth, simple structure and a well bending characteristic, in which confinement loss (CL) is ∼ 0.15 dB/km @ 1.55 µm and the bandwidth is ∼ 220 nm @ CL < 1 dB/km. The bending loss (BL) is lower than ∼ 1 dB/km @ bend radius rc > 24 mm at 1.55 µm. Therefore, the HC-ARF with NSRs has potential applications of data transmission, sensing, high power delivery and so on.
Custom silicon technology for SPAD-arrays with red-enhanced sensitivity and low timing jitter
Authors: Gulinatti Angelo , Ceccarelli Francesco , Ghioni Massimo , Rech Ivan
Published: December 2020

Single-photon detection is an invaluable tool for many applications ranging from basic research to consumer electronics. In this respect, the Single Photon Avalanche Diode (SPAD) plays a key role in enabling a broad diffusion of these techniques thanks to its remarkable performance, room-temperature operation, and scalability. In this paper we present a silicon technology that allows the fabrication of SPAD-arrays with an unprecedented combination of low timing jitter (95 ps FWHM) and high detection efficiency at red and near infrared wavelengths (peak of 70% at 650 nm, 45% at 800 nm). We discuss the device structure, the fabrication process, and we present a thorough experimental characterization of the fabricated detectors. We think that these results can pave the way to new exciting developments in many fields, ranging from quantum optics to single molecule spectroscopy.
Generation of vector beams of Bell-like states by manipulating vector vortex modes with plasmonic metasurfaces
Authors: Zeng Xiang-Yu , Zhang Yu-Qin , Zhang Rui-Rui , Ren Xiao-Rong , Zhan Zi-Jun , Gu Man-Na , Sun Rui , Liu Chun-Xiang , Cheng Chuan-Fu
Published: December 2020

Metasurfaces with orthogonal nano-slit pairs arranged on spirals are proposed to generate vector beams (VBs) of Bell-like states and slanted polarizations. The design of the metasurfaces is based on the theoretically derived parameter condition for manipulation of the two vector vortex modes, which is satisfied by matching the three parameters of rotation order

m

, the spiral order

n

, and incident polarization helicity

σ

. The linear polarization states of the VBs are controlled by the initial orientation angle

φ
0

of slit pairs. VBs of satisfying quality are experimentally obtained, with the analytical and simulated results validated.
Knowledge, attitudes, and practices toward COVID-19 among university students in Japan and associated factors: An online cross-sectional survey
Authors: Hatabu Asuka , Mao Xinhua , Zhou Yi , Kawashita Norihito , Wen Zheng , Ueda Mikiko , Takagi Tatsuya , Tian Yu-Shi
Published: December 2020

The coronavirus disease (COVID-19) pandemic has greatly altered peoples’ daily lives, and it continues spreading as a crucial concern globally. Knowledge, attitudes, and practices (KAP) toward COVID-19 are related to individuals’ adherence to government measures. This study evaluated KAP toward COVID-19 among university students in Japan between May 22 and July 16, 2020, via an online questionnaire, and it further investigated the associated determining KAP factors. Among the eligible respondents (n = 362), 52.8% were female, 79.0% were undergraduate students, 32.9% were students whose major university subjects were biology-related, 35.4% were from the capital region, and 83.7% were Japanese. The overall KAP of university students in Japan was high. All respondents (100%) showed they possessed knowledge on avoiding enclosed spaces, crowded areas, and close situations. Most respondents showed a moderate or higher frequency of washing their hands or wearing masks (both at 96.4%). In addition, 68.5% of respondents showed a positive attitude toward early drug administration. In the logistic regressions, gender, major subjects, education level, nationality, residence, and psychological factors (private self-consciousness and extroversion) were associated with knowledge or attitudes toward COVD-19 (p < 0.05). In the logistic and multiple linear regressions, capital regions, high basic knowledge, high information acquisition, correct information explanations contributed positively to preventative action (p < 0.05). Non-capital regions, male gender, non-bio-backgrounds, high public self-consciousness, high advanced knowledge, incorrect information explanations, and high extroversion contributed negatively to self-restraint (p < 0.05). Moreover, self-restraint was decreasing over time. These findings clarify the Japanese university students’ KAP and the related factors in the early period of the COVID-19 pandemic, and they may help university managers, experts, and policymakers control the future spread of COVID-19 and other emerging infections.
El urbanita tecno-nómada y la Ciudad excluyente
Authors: Cacsire Grimaldos Rubén Arturo , Trachana Angelique
Published: December 2020

Partiendo de un análisis de la evolución de la ciudad industrial a la ciudad posindustrial en la era global y desde una perspectiva interdisciplinar, se trata de describir y argumentar cómo la vida urbana se desprende de las estructuras sólidas y estables de la ciudad; demostrar la eminente separación entre lo vivido y lo construido. Las diferentes movilidades y la inestabilidad en todos los aspectos de la vida, desde lo familiar, privado e íntimo a lo relacional, público y laboral las relaciones se vuelven “líquidas” en la gran ciudad y se van perdiendo los referentes estables. Las nuevas tecnologías digitales y las comunicaciones promueven la vida móvil. El nuevo urbanita tecno-nómada, categoría que incluye el inmigrante precario, el turista, el habitante que se convierte en turista en su propia ciudad y todo un elenco de especies urbanas que buscan oportunidades en la gran ciudad, experimentan el desarraigo, el individualismo y las instituciones debilitadas. En un mundo conectado a distancia a las redes trasnacionales, las grandes ciudades desconectadas interiormente fomentan grandes rupturas, discontinuidades y exclusiones. El método de abordaje de este estudio enfoca el “urbanita” en vez del habitual enfoque del urbanismo en un emergente contexto socio tecnológico y trata de definir cómo se construyen las subjetividades.
Espacialidad corpórea. Trasvases entre vestimenta y arquitectura
Authors: Martín López Lucía , Martínez de la Cruz Carmelina De Jesús
Published: December 2020

Se entiende la moda como un conjunto de dispositivos efímeros usables cuyos aprendizajes a nivel conceptual, estructural, material, semiótico, estético, económico, social y/o ambiental se inspiran muchas veces en la arquitectura y a su vez dejan huella en la concepción de esta, de modo que se tiene un proceso de ida y vuelta a lo largo de sus fases de creación. El objetivo de este texto se centra en remarcar las vías transversales a través de las cuales la moda y la arquitectura establecen diálogos conceptuales entre sí creando un trasvase de conocimiento. Para ello se presenta en primer lugar una actualización del estado de la cuestión del tema a través de la organización de la bibliografía y una comparación histórica que es válida para cualquiera de las dos disciplinas. En segundo lugar, se muestra una clasificación de los textos de acuerdo tres categorías repetidas numerosas veces en estos: la arquitectura y la vestimenta como terminales de información; como envolventes naturales-artificiales; y su relación con el binomio tipología-topología. A través de la investigación hermenéutica, este artículo trata de continuar el diálogo en torno a ambas disciplinas a través de estos tres entendimientos.
La ciudad futura como ruina. Representación en la bande dessinée de la arquitectura y la destrucción urbana en Bruselas Le Dernier Pharaon como síntesis
Authors: Ruiz Sánchez Javier
Published: December 2020

Bruselas, como una de las capitales del cómic europeo, ha sido y es escenario de múltiples historias dibujadas, a la vez que reconocida como un ejemplo de renovación urbana extrema durante las décadas de posguerra europea, hasta el punto de haberse acuñado un término, Bruxellization, como sinónimo de destrucción sistemática de la memoria urbana y del patrimonio existente en favor de la modernización. Este tema ha sido recurrente en bastantes autores de cómic belga, abordado de manera crítica en diálogo con el activismo urbano que, sobre todo a partir de los años setenta, consiguió invertir el proceso. La obra gráfica de François Schuiten mantiene como uno de los ejes fundamentales el tema de la destrucción de la ciudad en los ejercicios de anticipación que lleva a cabo, en particular en la serie Les Cités obscures, con Benoît Peeters como guionista, y de manera más intensa en una obra clave, Brüsel. En Brüsel recrea de forma más que explícita el Palais de Justice de Bruselas como ejemplo de dicho proceso. Schuiten ha editado en 2019 una personal visión de la serie clásica Blake et Mortimer, de Edgar P. Jacobs, el álbum Le Dernier Pharaon, donde se concentra en el Edificio del Palacio de Justicia y lo pone en diálogo con una importante tradición arquitectónica, la de la representación de la arquitectura futura como ruina, un ejercicio romántico cuyo máximo exponente es la obra gráfica del arquitecto visionario Joseph Michael Gandy en sus encargos por John Soane de las visiones futuras de sus obras.
Mosaicos económicos. Género y economía
Authors: Cabeza Laura , Egido Mónica
Published: December 2020

Este libro nace con la voluntad de contribuir a la divulgación de resultados de la investigación científica en economía entre lectores de otras disciplinas y el público en general. La comunicación de los avances de la economía y la administración de empresas a través de imágenes y mensajes cortos permite que la relación y la comunicación entre la Universidad y la sociedad sea más fluida. Trasladar mensajes económicos a través de imágenes es un campo poco explorado en la actualidad, pero debe ser un camino a considerar, dado el dinamismo y la rapidez con la que se mueve la información en el siglo XXI. La combinación de estructuras plásticas y de ideas abstractas de pensamiento lógico pueden fundirse para trasladar un mensaje subliminal que persuada y mueva conciencias. Dentro de las economías más avanzadas, la desigualdad afecta no tanto al acceso al trabajo, como a la brecha salarial de género, al denominado techo de cristal, o límite autoimpuesto por la mujer ante el cuidado de los hijos, al acceso a los puestos de alta dirección y a los consejos de administración, es decir, a los trabajos con mayor remuneración y capacidad de decisión. Todo ello lleva a la necesidad de seguir realizando políticas públicas que protejan a la mujer, políticas de conciliación y teletrabajo, políticas de igualdad, políticas contra la brecha salarial. Todo esto se aborda en este libro de forma plástica y directa.
Algunas notas más en torno a la categoría de cine poético
Authors: Pérez Bowie José Antonio
Published: December 2020

Vuelvo de nuevo sobre la categoría de cine poético, sobre la que ya había reflexionado en anteriores trabajos, e intento sistematizar las aproximaciones teóricas en torno a la misma y conectarlas con la actividad de los cineastas que cultivan esa modalidad cinematográfica. Parto de una distinción básica entre poeticidad absoluta (vinculada a la antinarratividad) y poeticidad relativa (que relaciono con una narratividad mitigada) y llevo a cabo un breve recorrido histórico por las manifestaciones principales de ambas y por las teorías surgidas en torno a ellas.
Voz y voto: participación política y calidad de la democracia en México
Authors: Holzner Claudio A.
Published: December 2020

RESUMEN: La igualdad intrínseca de cada ciudadano es una suposición fundamental de cualquier sistema democrático. Por esto, cualquier evaluación de la calidad de la democracia tiene que considerar la «igualdad de voz», o sea, el grado en que los ciudadanos tienen oportunidades más o menos iguales de participar en la toma de decisiones colectivas. Este ensayo hace una evaluación de la calidad de la democracia en México con especial atención a las desigualdades que existen en la participación política de ciudadanos con niveles de ingresos altos y bajos. Los pobres en México votan menos y participan menos que los ciudadanos de mayores recursos económicos en actividades políticas dirigidas directamente a los gobernantes. Cuando participan tienden a hacerlo en actividades con poca capacidad de comunicar información sobre sus preferencias o de presionar a las autoridades, produciendo las condiciones para que los gobiernos no respondan por igual a las demandas de todos los grupos sociales.ABSTRACT: Because intrinsic equality of each citizen is a fundamental assumption of democracies, any assessments of the quality of democracy must consider the equality of political voice, that is whether a political system provides citizens with more or less equal opportunities to participate in collective decisions. This essay examines patterns of political participation in Mexico to assess whether there are systematic inequalities in the abilities of Mexicans from different income groups to exercise their voice in the political process. The evidence shows that the poor in Mexico vote less often and participate less frequently in government-directed political acts than the wealthy. When they do participate, the poor do so in activities which have little capacity to inform about their needs and preferences, and with little capacity to put pressure on government officials. This creates conditions for governments to not be responsive to or representative of the demands of different social groups.
Foreword to first issue of the Aresty Undergraduate Research Journal
Authors: Levin Vadim
Published: December 2020

A unique resource for the Rutgers University community, the Aresty Research Center promotes the integral value of research in undergraduate education.This inaugural issue of the journal expands the scope of research activities the Center offers to Rutgers undergraduates to include the peer-reviewed publication process – a crucial element of any structured research activity. Students can engage with the journal in a variety of roles that all professional researchers take at different times – those of the authors of scholarly publications, those of peer reviewers who ensure the quality and soundness of the published work, and those of editors who coordinate the review process.
Targeting the Epigenetic Factors of Neuroinflammation
Authors: Patil Anusha
Published: December 2020

Currently, there are no effective treatments for traumatic brain injury (TBI). This is because the mechanisms behind post-injury neuroinflammation are not well understood. This project studies a novel signaling pathway responsible for the activation of microglia post-TBI. Its goal is to identify epigenetic factors of neuroinflammation that may be targeted with future therapies.

We are examining the possibility that class IIa Histone Deacetylases (HDACs), particularly HDAC7, are responsible for initiating the inflammatory response after TBI. In addition, we plan to explore what its upstream regulation factors may be. One possible upstream regulation factor explored is regulating Kinase 2, also known as Par1b (Par1b/MARK2), since prior research indicates that a deficiency in Par1b/MARK2 increased the inflammatory response of microglia in a mouse model of TBI. In our experiments, we examined brains from sham mice (i.e., without head injury) and mice subjected to closed head injury (CHI). Our experiments made use of wild-type mice and mice deficient in Par1b/MARK2. Qualitative analyses were conducted using fluorescent microscopy imaging of immunohistochemistry. Using cell-specific markers of inflammation, we found an increase in astrocytic marker GFAP (glial fibrillary acidic protein) and microglial protein IBA1 (ionized calcium binding protein) expression in the cortex of the mice after CHI. These increases were dramatic ipsilaterally (same side) to the injury, but only moderate contralaterally (opposite side). In the control brains (sham operates), little to no increase in these markers were detected.

In our experiments, we observed increased expression of HDAC7 in post-TBI microglia as well as in reactive GFAP-expressing astrocytes. Others have observed that Par1b/MARK2 may negatively regulate HDAC7 activity and there is evidence that HDAC7 is an inhibitor of anti-inflammatory genes.
MODEL FOR EVALUATION OF SERVICE-MANAGEMENT TOOLS IN THE OIL AND GAS INDUSTRY
Authors: Pretterhofer Marco , Mezhuyev Vitaliy I. , Welsh Dominic
Published: December 2020

Companies providing services for customers on-site require appropriate scheduling of employees and technicians. The availability, skills and experience of employees and travel times need to be considered. In addition, the required information should be made available as efficiently as possible. As a result of an increasing rate of digitalization, companies are changing from manual planning in Microsoft Excel or on planning boards and printed documents to integrated workforce management tools that automate planning steps and provide relevant documents. The market for these software tools is growing rapidly. In addition to established software providers such as SAP and Oracle, there are also small vendors on the market. Companies that decide to deploy their field service planning with an appropriate tool are faced the challenge of choosing a suitable method for the evaluating and analyzing the market. The paper is devoted to development of the model for the evaluation of software tools in the context of field service management in the oil and gas industry. The first step of proposed methodology involved market screening to identify suitable software tools. In the next step, criteria were defined that needed to be tested to compare the tools. Finally, the outcome of the evaluation and additional requirements allowed for a benefit analysis. After the evaluation model was developed, it was applied on five selected software tools. SAP Field Service Management was ranked as the best product for a defined use case. The tools from Odyssee and Salesforce ranked similarly in the categories that refer to the functional aspects. The field service management tools from Fergus and ReachOut are both available for free with very limited functionalities, and reached rank four and five, respectively. The result of this work can be used by companies providing services in the oil and gas industry to evaluate field service management tools. Following the model, a structured process is provided to reduce the time needed for software evaluation. Future studies can build on this work and focus either on different software tools or a different industry.
La experiencia de las imágenes marianas a finales de la Edad Media: el Miroir Historial de Vicente de Beauvais
Authors: Murcia Nicolás Fuensanta
Published: December 2020

Las imágenes de culto adquieren un gran protagonismo a finales de la Edad Media gracias a la legitimación de su carácter sagrado y milagroso. Un caso extremadamente interesante son las efigies marianas ,que no solo se ven favorecidas por estas circunstancias sino también por la experiencia devocional que suscita su modelo, la Virgen. El presente artículo pretende explorar la representación de estas imágenes en los manuscritos del Miroir Historial, la traducción del Speculum Historiale realizada en el siglo XIV por Jean de Vignay. En sus miniaturas vemos cómo estas van perdiendo su condición de objeto para pasar a ser figuras “casi vivientes”, situadas a un mismo nivel de realidad que el protagonista, una presentación ligada a los rasgos del personaje que representan y la búsqueda de una religiosidad más próxima. Así pues, la Virgen, mediadora cercana por excelencia, deja de ser representada a estarpresente en su imagen, la cual ya no es una simple escultura o pintura, sino más bien su sustituta eficiente y real.
La muerte de la alta costura española: crónica de un final
Authors: Rosés Castellsaguer Sílvia
Published: December 2020

Las décadas de 1950 y 1960 fueron un período de máximo esplendor para la moda española, gobernada por el sistema de la alta costura. Fue un momento en el que los creadores de moda en España, emplazados principalmente en Barcelona, alcanzaron una gran madurez creativa y prosperidad comercial, llevándolos a tener una gran presencia en los mercados internacionales. Esta etapa de esplendor se verá interrumpida, sin embargo, por conflictos con el régimen franquista, que, lejos de considerar el potencial económico y cultural del sector, tal y como sí hacían países como Francia o Italia, lo usará simplemente como un elemento de propaganda política y lo ahogará con múltiples cargas tributarias. Esta situación, agravada por un cambio de sistema en la moda que dará paso al prêt-à-porter, llevará al sector de la alta costura española a su muerte definitiva a finales de los años 1970.
Réplicas en Redes Sociales que Denuncian Desigualdades de la Estrategia #AprenderDigital en Tiempos de Covid-19
Authors: Lopera-Zuluaga Edwar Camilo
Published: December 2020

El Ministerio de Educación colombiano publicita en redes sociales la estrategia #AprenderDigital para contrarrestar el cierre masivo de escuelas por el covid-19. No obstante, la ciudadanía hace réplica inconforme a esta homogénea iniciativa. Esta investigación de enfoque cualitativo pretende, primero, clasificar en categorías de análisis las réplicas ciudadanas realizadas a las publicaciones del Ministerio Nacional de Colombia en Twitter y Facebook bajo la etiqueta #AprenderDigital. Segundo, discutir, en el marco de las réplicas ciudadanas, las expresiones de desigualdad educativa exacerbadas por la estrategia digital, además, de ofrecer algunas lecciones aprendidas para la política educativa digital pospandemia en Colombia. El método implicó recuperar las réplicas ciudadanas y los datos con apoyo del software de análisis cualitativo Atlas ti. Las réplicas fueron clasificadas en tres categorías: 1. Réplicas de acceso. 2. Réplicas curriculares. 3. Exhortaciones. Hacia el final, discutimos sobre la fortaleza del estudio para ratificar la desigualdad educativa en tiempos de covid-19, la homogeneidad de las políticas educativas de emergencia que niegan las diferencias, reflexionamos sobre las necesarias políticas de subjetividad y aportamos algunas reflexiones sobre la dirección de las políticas digitales pospandemia. Por último, valoramos la fertilidad que significa recuperar réplicas en redes sociales para la investigación en ciencias sociales.
Adaptación de las Metodologías Activas en la Educación Universitaria en Tiempos de Pandemia
Authors: Gómez-Hurtado Inmaculada , García-Rodríguez María del Pilar , González Falcón Inmaculada , Coronel Llamas José Manuel
Published: December 2020

La investigación realizada tiene por objetivo conocer, analizar y describir el proceso de adaptación de las metodologías didácticas activas ante el cambio de la docencia presencial a la docencia online, las actitudes del profesorado y sus valoraciones en torno a la experiencia vivida durante la pandemia del Covid-2019. La metodología de investigación ha sido cualitativa, realizando un estudio multicaso en cuatro grupos de estudiantes de grado y posgrado en la Universidad de Huelva. Las materias y grupos fueron seleccionados intencionalmente por estar basadas en metodologías activas, y estrategias y actividades prácticas para atender a la diversidad del alumnado, basándose así en los principios de la justicia social. El artículo plantea dilemas y alternativas de tres docentes universitarias en el desarrollo de la docencia ante la sobrevenida pandemia. Los resultados muestran valoraciones positivas por parte del profesorado, aunque se analizan también las dificultades. Destacan un aumento en su formación docente y una evolución efectiva en su desarrollo profesional, además de incrementar su labor investigadora centrada en la docencia. Las metodologías activas utilizadas presencialmente se han sustituido por otras estrategias y recursos didácticos que han permitido una docencia virtual basada en un proceso de enseñanza-aprendizaje activo y enriquecedor para todos los estudiantes.
Safety Huddle methodology development in patient safety software: an experience report
Authors: Mello Lucas Rodrigo Garcia de , Christovam Barbara Pompeu , Moreira Ana Paula Amorim , Moraes Erica Brandão de
Published: December 2020

ABSTRACT Objectives: to report the development and implementation of a digital tool developed by a group of nurses and information technology professionals working in healthcare quality management. Methods: an experience report regarding the development of the Safety Huddle digital model, using the agile Scrum methodology. Results: the first stage was the development of the model proposed by the team of nurses and IT professionals, based on the demand of quality and patient safety leaders in Brazil, and the second phase was the software implementation. Final Considerations: the development and implementation of the Safety Huddle contributed to expedite the detection and distribution of actions, in addition to promoting integration among teams, accountability, and empowerment of professionals to foresee and identify issues related to patient safety and face them through action plans.
VIOLÊNCIA INTRAFAMILIAR CONTRA CRIANÇAS E ADOLESCENTES: INTERCONTEXTUALIDADE DE SIGNIFICADOS VERBAIS E IMAGÉTICOS
Authors: Rodrigues Johwyson da Silva
Published: December 2020

Resumo Este trabalho objetiva investigar traços da violência intrafamiliar contra crianças e adolescentes presentes nos significados verbal e visual do jogo digital The Binding of Isaac (2011), ressaltando, assim, sua multimodalidade. Como aporte teórico-metodológico, foram utilizados fundamentos da Análise Crítica do Discurso (ACD) e da Gramática do Design Visual (GDV) para detectar possíveis processos visuais, intertextualidades e interdiscursividades que pudessem revelar pistas da violência intrafamiliar contra crianças e adolescentes como prática social presente no jogo. Os resultados obtidos confirmam que a personagem principal possui todas as características comuns às vítimas que sofrem desse tipo de abuso. Concluiu-se, também, que o jogo em questão, como um veículo de comunicação, possui a função, para quem o joga, de apresentar e alertar sobre o tema. Espera-se que este estudo possa contribuir ainda mais para a consolidação da Semiótica Social, com o apoio da ACD como um aporte teórico-metodológico eficiente na investigação de práticas sociais.
CAPA, ORELHAS E QUARTA CAPA COMO ESPAÇOS ENUNCIATIVOS DE PROMOÇÃO DE OBRAS LITERÁRIAS
Authors: Linhares Vinícius Lourenço
Published: December 2020

Resumo A partir da aproximação entre teoria da enunciação e o processo de produção e editoração do livro, este artigo analisa a encenação de alguns agentes envolvidos na cadeia editorial do livro O sol na cabeça, do escritor brasileiro Geovani Martins, relativamente à promoção/divulgação e difusão do referido livro. Embasam este trabalho as discussões de Araújo (2012), Cavallo e Chartier (2001), Chartier (1998) e Thompson (2012) sobre processos de edição. As discussões envolvendo a enunciação estão calcadas nos estudos de Benveniste (1989; 1995), Bakhtin/Volochínov (2009) e Bakhtin (2010), além de se valer da visão de Marx (1996) sobre a mercadoria no contexto da economia capitalista.
Caracterización de preguntas en libros de texto de Ciencias Naturales en Educación Primaria chilena
Authors: Sepúlveda Alejandro , Minte Andrea , Díaz-Levicoy Danilo
Published: December 2020

Resumen La formulación de preguntas es una actividad frecuente en los procesos de enseñanza y de aprendizaje. Su promoción es una tarea relevante en las aulas tanto en contextos orales como escritos. De acuerdo con lo anterior, el presente trabajo da cuenta de los resultados obtenidos en una investigación de las dimensiones del proceso cognitivo que demandan las preguntas formuladas en los libros de texto de Ciencias Naturales para estudiantes de Educación Primaria chilena. Se trató de una investigación con método cuantitativo, en la cual se clasificaron los tipos de preguntas de acuerdo a la dimensión del proceso cognitivo, que demandan a los estudiantes. Se utilizó como base la taxonomía de Anderson y Krathwohl (2001), con la finalidad de evaluar las preguntas presentes en los libros de texto actuales, específicamente, en el contenido y en las actividades didácticas propuestas. Se trabajó con el total de preguntas correspondiente a 1256. Se analizaron estadísticamente con el software SPSS (15.0). Entre los hallazgos se puede señalar que las preguntas contenidas en los libros de texto de Ciencias Naturales promueven, mayoritariamente, la dimensión más elemental de la taxonomía, recordar información y, en menor medida, las dimensiones cognitivas superiores: crear, evaluar y aplicar. Cabe destacar que no se constatan diferencias estadísticamente significativas entre las demandas de las preguntas formuladas en los textos de los diferentes cursos estudiados.
Zay Anna Herbáriuma és a XVIII. századi magyar gyógyszerészi szaknyelv
Authors: Szabó Attila
Published: December 2020

By the end of the 17th century, the Ottoman Empire power had been expelled out of Hungary. At the same time, the death of the King of Spain, forecast the end of the “Western” Habsburg Empire. Emerging economic nations England and the Netherlands wanted to create a new balance of power in which the Principality of Transylvania was also concerned. The Spanish War of Succession ended with the peace of Utrecht, which created a modern style of diplomacy. Ferenc Rákóczi II realized the chance of Hungary’s independence in a rearranging Europe, thus he started his war of independence. One of the spectacular social rise families of the era was the Vay family. Adam Vay wanted to be out of the war of independence. However, when the imperial troops burned down Gács Castle, he joined Rákóczi. Rising to the rank of general, Vay went to exile with his family in Poland after the peace of Szatmár (present-day Satu Mare, Romania). In exile, not only deprivation but also disease threatened them. Typical for the manorial courts of the era, scholar and lay healers worked together. His well-read wife, Anna Zay, began writing herbarium following this tradition. She tried most of the recipes he collected among the personnel of her house. Her work was circulated as a manuscript copy, which preserved the 16th – 17th-century Hungarian medical language. For the people of this era, above the battlefield injuries, the most feared disease was the plague. For Zay, prayer strengthened her endurance, helped her bearing much suffering and sorrow and provided hope to be freed from her exile. God speaks to man through the word, but prayers speak to God.
ERASMUS 2021-2027 – az Európai Unió új, oktatási, képzési, ifjúsági és sportprogramja
Authors: Szitáné Kazai Ágnes
Published: December 2020

In May 2018, the European Commission released its proposal for the next Erasmus programme with a doubling of the budget to 30 billion euros for the period 2021-2027. The new programme will ensure the continuation of the Erasmus+ programme for education, training, youth and sport. The Erasmus programme 2021-2027 will focus on inclusiveness and reaching more young people from disadvantaged backgrounds. The next programme will maintain the same basic structure as the previous one with 3 key actions (KA): - KA1 will cater for learning mobility; - KA2 will focus on cooperation among organisations and institutions; - KA3 will support policy development and cooperation. The objectives will also be pursued through Jean Monnet actions..
La norma linguistica nell’epoca dei social network: da petaloso a scendi il cane
Authors: Frenguelli Gianluca
Published: December 2020

Con l’avvento dei moderni mezzi di comunicazione di massa e, soprattutto, dei social network, le dispute linguistiche hanno assunto attori e prassi completamente diversi rispetto al passato: dalle accademie il dibattito si è ormai trasferito su internet e sui giornali, coinvolgendo un pubblico non specialista, ampio e diversificato per composizione e livello d’istruzione, il quale ha profondamente cambiato le modalità con cui vengono affrontate le questioni relative alla norma. Attraverso l’analisi di alcune di dispute linguistiche salite agli onori della cronaca in questi ultimi anni, il contributo si propone di tracciare i nuovi percorsi e di comprendere i nuovi modi in cui si sviluppa ai giorni nostri il dibattito sulla norma linguistica, sia nei media tradizionali, sia nei Social media.
HuBMAP TMC-UF Validation of Custom conjugated Antibodies for CODEX v1
Authors: Jorgensen Marda , Nick Jerelyn
Published: December 2020

This protocol describes the methods for validating antibodies after custom conjugation with Akoya CODEX barcodes in FFPE tissues on coverslips. Included are the stepwise protocols for pre-staining, deparaffinization, antigen retrival, antibody staining, post-fixation, manual addition of CODEX Reporters and tissue mounting on microscope slides. The recommended single stain experimental design includes 3 tissues sections from the same block stained with the CODEX-tagged antibody alone (1), co-stained with a positive control(2), and co-satined with a negative control(3). Tissue 1 Tissue 2 Tissue 3 CODEX-Stain Only CODEX-stain with co-stain (Positive Control) CODEX-stain with counter-stain (Negative Control) DAPI Channel Nuclear Stain Nuclear Stain Nuclear Stain 2nd Fluorescent Channel CODEX-tagged Anitbody CODEX-tagged Anitbody CODEX-tagged Anitbody 3rd or 4th Fluorescent Channel None Control antibody targeting a different antigen expressed by the same phenotype or cell population Control antibody targeting an antigen expressed by a different phenotype or cell population. The enitre process requires approximately 5.5 hours, including a 2 hour incubation. Except as noted, reagents and consumables should be prepared before begining the protocol.
‘Frankenstein’ protocol for nuclei isolation from fresh and frozen tissue for snRNAseq v3
Authors: G Martelotto Luciano , Martelotto Luciano
Published: December 2020

This protocol is the result of the combination of various nuclei isolation protocols for single cell RNA-seq experiments using droplet-based methods, hence the name Frankenstein. Developed to prepare nuclei isolates from small sample sizes (as little as a grain of rice), this protocol uses FACS to identify cell subpopulations based on ploidy (e.g. tumor versus stroma), to ensure that nuclei suspensions are not clumped, and to remove any debris, especially ambient RNA, to help reduce background. The reference protocols can be found in the following papers: Hu, et al., Habib, et al. (2016), Habib, et al. (2017), Lake, et al., and Lacar, et al. This protocol is routinely used in the single-cell innovation lab for single nuclei experiments using 10x Genomics technologies. The protocol has been demonstrated to work successfully with fresh, snap/flash frozen, cryopreserved cells, and cell lines, as well as various solid cancers: pancreas, pheochromocytomas, paragangliomas, breast cancer, lymphoma, xenografts and tumors.
CONCEPTUAL CONFLICT BETWEEN THE FOUNDERS OF THE PEREYASLAV SKANSEN REGARDING ITS NAME AND THEMATIC STRUCTURE (IN THE LATE 1950es AND 1960es)
Authors: Zham Olena
Published: December 2020

Monumental and museum work in Ukraine in 1960-1970's of XX century. characterized by a wave of mass interest in Ukrainian culture and the spread of the progressive idea of creating ethnographic museums of a new type – open-air museums, commonly called scans. The first such museum in Ukraine was the Museum of Folk Architecture and Life in the Middle Dnieper region in Pereyasla, Kyiv region, which is one of the richest treasures of original folk architecture and life of the inhabitants of the Dnieper villages of the 19 th – beginning оf the 20 th. The museum is a part of National historical and ethnographic reserve «Pereyaslav».
This project had no precedents in Ukraine, so the path to the realization of this idea was difficult and long. Foreign experience in creating open-air ethnographic exhibitions was especially useful, as the museum practice of Ukraine still lacked theoretical knowledge, polished methodology, clear principles of museum studies, international standards, and good work experience. The approaches of Pereyaslav museums to this new, methodically and practically not developed business, were creative and original. The experience of its founders was useful for creating other museums of folk architecture and life in Ukraine.
The article examines the history of the Pereyaslav scansen. Different conceptual approaches of its founders are analyzed. The proposed article deals, first of all, with the scientific controversy between the director of the Pereyaslav-Khmelnytsky State Historical Museum M.I. Sikorsky and public figure E.F. Ishchenko regarding the definition of the type of museum, its name, thematic structure, exposition content, landscaping and other issues. Scientific discourse also had its positive sides. The controversy that arose between the founders allowed both sides to consider true, logical ideas in the theory of each of them. Scientific discourse also had its positive sides. The controversy that arose between the founders allowed both sides to consider true, logical ideas in the theory of each of them.