bluuebunny/crossref_metadata_2025 huggingface dataset:
Yalın ve Karışık Olarak Yetiştirilen Bazı Ekmeklik Buğday ( Triticum aestivum L.) Çeşitlerinin Verim ve Kalite Özellikleri ile Ekonomik Getirilerinin İncelenmesi
Authors: İPEKSEVER Fahriye , ÖZBERK İrfan
Published: December 2019

Bu çalışmada Şanlıurfa ilinde yetiştirilen bazı ekmeklik buğday çeşitlerinin yalın veya karışım olarak ekiminin verim ve kalitede istikrar ile kârlılığa etkilerinin araştırılması amaçlanmıştır. Tarla denemeleri GAPTEAM Talat Demirören Araştırma İstasyonunda 2017-2018 üretim yılında 9 farklı çeşit ve bunların paçallarından oluşan 10 konu; yani toplamda 19 karışım ve yalın çeşit ile tesadüf blokları deneme desenine göre 4 tekerrürlü olarak yürütülmüştür. Verim, kalite, pazarlama fiyatları ve kârlılık gibi özellikler varyans, korelasyon ve regresyon analizleri yolu ile incelenmiştir. Elde edilen bulgulardan; tüm karışımların verim ortalaması dikkate alındığında (541.50 kg/da) yalın çeşitlerden (494.16 kg/da) daha yüksek olduğu, ancak verimde ilk sırayı Dariel’in (668.75 kg/da) aldığını Dariel ve Ceyhan-99 ‘un %90(%45:%45) oranda yer aldığı 6 nolu karışımın verim bakımından 2. Sırada (622.75 kg/da) yer aldığı anlaşılmıştır. Yalın çeşitler verim ve kalite ile ilgili özellikler bakımından en yüksek ve en düşük değerlere sahip olarak büyük dalgalanma göstermişlerdir. Karışımlar genellikle daha az dalgalanma göstermiş ve istikrarlı bulunmuşlardır. İncelenen özellikler bakımından karışım ve yalın çeşitlerin genel ortalamaları arasında istatistiksel önemde fark bulunmamıştır. Pazarlama fiyatı olarak tüm karışımların ortalamasının (1.218 TRY) yalın çeşitlerden (1.162 TL) daha üstün olduğu anlaşılmıştır. Ancak yalın çeşitlerden Dariel (1.288 TL/kg) pazarlama fiyatı bakımından ilk sırada yer almıştır. Dekara gelir bakımından karışımların genel ortalaması (651,82 TL/da) yalın çeşitlerden (582,49 TL/da) üstün bulunmuştur. Ancak en yüksek dekara gelir yalın çeşit Darıel’den (861,16 TL/da) elde edilmiştir. 6 nolu (%45 Ceyhan 99 + %45 Dariel + %5 Sagitario + %5 İthal) karışımı 758,07 TL/da dekara gelirle 2. sırada yer almıştır. Dekara gelir, tane verimi ve pazarlama fiyatını etkileyen tüm karakterler arasında istatistiksel önemde pozitif veya negatif korelasyonlar tespit edilmiştir. Dekara verim ile verimi etkileyen tarımsal özellikler, pazarlama fiyatı ile pazarlama fiyatını etkileyen kalite özellikleri arasındaki regresyon eşitlikleri düşük determinasyon katsayısı değerleriyle güvenilir bulunmamıştır. Dekara gelir ile verim ve kaliteyi etkileyen tüm özellikler arası regresyon eşitlikleri de verim dışında düşük determinasyon katsayısı değerleri vermiştir. Tane verimi ve kârlılık arasındaki regresyon eşitliği yüksek determinasyon katsayısı (%92.5) ile yüksek verimli çeşit veya karışımların yüksek dekara gelire sahip olduğunu göstermiştir. K6 karışımının verim, kalite ve dekara gelir yönünden yalın çeşitler ile rekabet edebileceği ve çiftçilere önerilebileceği anlaşılmıştır.
Biarkan Perempuan Bicara: Analisis Kekuatan Metode Life History dalam Menghadirkan Pengalaman dan Pengetahuan Perempuan dalam Penelitian Ann Goetting
Authors: Musarrofa Ita
Published: December 2019

Women's experience and knowledge are two substantive things that must be a concern in order to reconstruct the reality of women, in order to overcome the bias of the roles of men and women in life. This paper aims to examine subjective methods that are able to see the reality of women from the lens of women's experience and knowledge so that women have strategic value in their own lives. This study uses field research methods, with data collection techniques from a variety of narratives of women's life history narratively with life history data analysis techniques. This study produces findings that the method of life history is able to identify the subjective experiences of women in constructing their own reality, based on the root experiences of violence that befell them. Second, women's experiences and knowledge about violence can be utilized as a conscious effort to deal with violence, dare to speak out injustice, and rise from the violence they experienced.
Pengaruh Model Pembelajaran Discovery Learning dengan Pendekatan Kontruktivisme terhadap Peningkatan Hasil Belajar Matematika Siswa
Authors: Tahir Tahir , Marniati Marniati
Published: December 2019

Tujuan dari penelitian ini adalah untuk mengetahui perbedaan peningkatan hasil belajar matematika siswaantara siswa yang belajar menggunakan model pembelajaran discovery learning dengan pendekatan kontruktivisme dengan siswa yang belajar menggunakan model pembelajaran konvensional. Penelitian ini merupakan penelitian eksperimen yang bertujuan untuk mencari pengaruh perlakuan tertentu terhadap yang lain dalam kondisi yang terkontrol. Hasil penelitian diuji menggunakan uji hipotesis untuk mengetahui adanya perbedaan hasil belajar siswa antara siswa yang belajar menggunakan model pembelajaran discovery learning dengan pendekatan kontruktivisme dengan siswa yang belajar menggunakan model pembelajaran konvensional. Selain itu juga digunakan analisis statistik deskriptif untuk melihat perubahan sebelum dan sesudah perlakuan. Dari hasil penelitian menggunakan uji hipotesis dan analisis statistik deskriptif menunjukkan bahwa terdapat perbedaan peningkatan hasil belajar siswa yang belajar menggunakan model pembelajaran discovery learning dengan pendekatan kontruktivisme dengan siswa yang diajar dengan menggunakan model pembelajaran konvensional. Model pembelajaran discovery learning dengan pendekatan kontruktivisme dapat meningkatkan kemampuan belajar siswa sehingga terdapat perbedaan yang cukup signifikan antara kelompok siswa yang belajar menggunakan model pembelajaran discovery learning dengan pendekatan kontruktivisme dan kelompok siswa yang belajar dengan pembelajaran konvensional.
Kemampuan Berfikir Kritis Matematis Siswa dengan Menggunakan Model Collaborative Learning dengan Pendekatan Open-Ended Berbantuan Media Macroflash 8
Authors: Janah Ika Nur , Kusumadewi Rida Fironika , Ulia Nuhyal
Published: December 2019

Kemampuan berfikir kritis matematis merupakan kemampuan berfikir dalam menyelesaikan suatu masalah yang melibatkan pengetahuan, penalaran, dan pembuktian matematika. Namun pada kenyataannya kemampuan berfikir kritis matematis siswa kelas V SD Negari Sembungharjo 01 masih rendah. Tujuan dari pembelajaran ini adalah agar kemampuan berfikir kritis matematis siswa berkembang setelah pembelajaran dengan model collaborative learning berpendekatan open-ended berbantuan media macroflash 8. Penelitian ini menggunakan desain Quasi Experimental Design dengan bentuk pretest-posttest control group design Hasil penelitian menunjukkan bahwa: (1) kemampuan berfikir kritis matematis siswa kelas eksperimen menggunakan model collaborative learning berpendekatan open-ended berbantuan media macroflash 8 lebih baik atau sama terhadap siswa kelas kontrol dengan menggunakan model ekspositori, dibuktikan dengan hasil -t tabel (-2,034) ≤ t hitung (1,503) ≤ t hitung (2,034) sehingga Ho ditolak dan Ha diterima diartikan terdapat perbandingan nilai pretest dan posttest pada kelas eksperimen dan kelas kontrol pada uji-t. Dalam penelitian ini dapat disimpulkan bahwa setelah diberikan pembelajaran model collaborative learning berpendekatan open-ended terdapat perbedaan hasil dari sebelum dan sesudah pembelajaran terhadap kemampuan berfikir kritis matematis.
Practical Aspects of Quality Management in the Construction Industry
Authors: Emel'yanovich Anzhelika , Koval Sergey , Kakorin Alexander
Published: December 2019

The authors consider the internal and external reserves of improving the quality of products at the enterprises that produce reinforced concrete. The research objective was to study and substantiate the external and internal factors, thus improving the effectiveness of quality management. The paper focuses on the use of such tool of sustainable development as "Six Sigma", which is considered as an important factor in product quality management. The paper also features the process of certification as an external tool that can improve quality management in the construction industry. The authors justified the necessity of mandatory certification of construction products when bidding for a tender. The paper also reviews the experience of sustainable production at reinforced concrete plants. The problems of product quality in the industry are of strategic nature and can cause economic, environmental, and other negative consequences. Quality management should become compulsory in the industry since its products are designed exclusively for the domestic market. As a result, its certification according to State Standards ISO 9001 or GOST R ISO 9001 is absolutely voluntary and performs only image-making functions. As far as tenders for state orders are concerned, mandatory certification may solve the existing problems with the quality of construction work. As internal quality management tool, the concept of "Six Sigma" can be useful for concrete works.
Dynamics of Investment Attractiveness of the Kemerovo Region in 2008–2017
Authors: Lazorenko Alexander
Published: December 2019

Investment attractiveness of a region is a complex category, which describes various angles of the state of the socio-economic sphere. Investment attractiveness has two-level structure: organization level and state / region level. At the moment there is no consensus on the essence of this category, and there is also no unified system of indicators characterizing the investment attractiveness of an organization or region. Increasing the investment attractiveness of a region may affect various aspects of life of its population, e.g. by attracting investors to various local projects. The author analyzed scientific literature describing the essence of investment attractiveness and its structure. The paper introduces a system of indicators of investment attractiveness, which includes five groups of indicators that characterize the investment potential of the area. The system is based on scientific publications and system of indicators of investment attractiveness developed by the Expert-RA rating agency. The paper also includes an analysis of the dynamics of the indicators in 2008–2017 and recommendations on how to increase the investment attractiveness of the Kemerovo Region.
Cell-Derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles?
Authors: Zacharia Effimia , Zacharias Konstantinos , Papamikroulis George-Angelo , Bertsias Dimitrios , Miliou Antigoni , Pallantza Zoi , Papageorgiou Nikolaos , Tousoulis Dimitris
Published: December 2019

Background:

Despite the recent advances in the treatment of Acute Coronary Syndromes (ACS), patients with ACS are still exposed to an increased risk for adverse cardiovascular events, while their prognosis is difficult to determine. Experimental and clinical studies have shown that cell-derived Microparticles (MPs) are associated with the underlying pathophysiological processes that are responsible for atherogenesis and may be causally implicated in the induction of atherothrombosis.

Objective:

In the present article, we aimed to review the available evidence regarding the predictive role of MPs in patients with ACS.

Results:

Evidence suggests that endothelial MPs are associated with future adverse cardiovascular events in patients with ACS. Platelet-derived MPs have been excessively studied, since they have been found to trigger the coagulation cascade; however, their role as predictors of future cardiovascular events remains debatable. The role of red blood cell-derived MPs is more intriguing; they have been proposed as markers of ongoing thrombosis in patients with ACS, while previous studies have shown that they have anti-coagulant properties in healthy individuals. Leukocyte-derived MPs may also have a predictive role, although the studies regarding these are still limited. Last but not least, it was an interesting discovery that circulating MPs can provide information regarding the angiographic lesions in patients with ACS.

Conclusion:

The concept of MPs as potential circulating biomarkers in patients with ACS holds much promise. However, large-scale clinical studies are required to evaluate whether the measurement of plasma MPs could be of clinical significance and, thus, dictate a more aggressive treatment strategy in patients with high levels of circulating MPs.
Current Position on the Role of Monomeric C-reactive Protein in Vascular Pathology and Atherothrombosis
Authors: Melnikov Ivan S. , Kozlov Sergey G. , Saburova Olga S. , Avtaeva Yulia N. , Prokofieva Lyudmila V. , Gabbasov Zufar A.
Published: December 2019

C-reactive Protein (CRP) is an acute phase reactant, belonging to the pentraxin family of proteins. Its level rises up to 1000-fold in response to acute inflammation. High sensitivity CRP level is utilized as an independent biomarker of inflammation and cardiovascular disease. The accumulating data suggests that CRP has two distinct forms. It is predominantly produced in the liver in a native pentameric form (nCRP). At sites of local inflammation and tissue injury it may bind to phosphocholine-rich membranes of activated and apoptotic cells and their microparticles, undergoing irreversible dissociation to five monomeric subunits, termed monomeric CRP (mCRP). Through dissociation, CRP deposits into tissues and acquires distinct proinflammatory properties. It activates both classic and alternative complement pathways, binding complement component C1q and factor H. mCRP actively participates in the development of endothelial dysfunction. It activates leukocytes, inducing cytokine release and monocyte recruitment. It may also play a role in the polarization of monocytes and T cells into proinflammatory phenotypes. It may be involved in low-density lipoproteins (LDL) opsonization and uptake by macrophages. mCRP deposits were detected in samples of atherosclerotic lesions from human aorta, carotid, coronary and femoral arteries. mCRP may also induce platelet aggregation and thrombus formation, thus contributing in multiple ways in the development of atherosclerosis and atherothrombosis. In this mini-review, we will provide an insight into the process of conformational rearrangement of nCRP, leading to dissociation, and describe known effects of mCRP. We will provide a rationalization for mCRP involvement in the development of atherosclerosis and atherothrombosis.
Transfer Effects of Working Memory Intervention on Linguistic Abilities in Patients with Dementia
Authors: Lee Mi Sook , Kim Bo Seon
Published: December 2019

Purpose: Working memory training for Alzheimer’s disease (AD) patients may yield everyday cognitive- linguistic benefits by facilitating transfer effects in multiple domains. The purpose of this study was to investigate the effects of working memory intervention and differences on transfer effects in type of intervention paradigm like core training (CT) and strategy training (ST).Methods: A total of 24 patients with mild and moderate AD were divided into CT and ST group (n = 12, respectively). After CT and ST interventions, we assessed their transfer effects on linguistic abilities including reading comprehension, figurative language, word fluency, and discourse production. Results: There were three main findings. Firstly, CT group improved significantly in figurative language, word fluency, and discourse production. Secondly, ST group showed the significant intervention gains in figurative language and discourse production. Thirdly, CT group had higher transfer effects in figurative language and discourse production than ST group, while both were similar in other transfer effects.Conclusion: This study proves that effects of working memory intervention for AD patients are different in type of paradigm, and thereby presents a roadmap for increasing the efficacy and utilization of working memory intervention in clinical settings.
Frequent Mobile Electronic Medical Records Users Respond More Quickly to Emergency Department Consultation Requests: Retrospective Quantitative Study
Authors: Jung Kwang Yul , Kim SuJin , Kim Kihyung , Lee Eun Ju , Kim Kyunga , Lee Jeanhyoung , Choi Jong Soo , Kang Mira , Chang Dong Kyung , Cha Won Chul
Published: December 2019

Background

Specialty consultation is a critical aspect of emergency department (ED) practice, and a delay in providing consultation might have a significant clinical effect and worsen ED overcrowding. Although mobile electronic medical records (EMR) are being increasingly used and are known to improve the workflow of health care providers, limited studies have evaluated their effectiveness in real-life clinical scenarios.

Objective

For this study, we aimed to determine the association between response duration to an ED specialty consultation request and the frequency of mobile EMR use.

Methods

This retrospective study was conducted in an academic ED in Seoul, South Korea. We analyzed EMR and mobile EMR data from May 2018 to December 2018. Timestamps of ED consultation requests were retrieved from a PC-based EMR, and the response interval was calculated. Doctors’ log frequencies were obtained from the mobile EMR, and we merged data using doctors’ deidentification numbers. Pearson’s product-moment correlation was performed to identify this association. The primary outcome was the relationship between the frequency of mobile EMR usage and the time interval from ED request to consultation completion by specialty doctors. The secondary outcome was the relationship between the frequency of specialty doctors’ mobile EMR usage and the response time to consultation requests.

Results

A total of 25,454 consultations requests were made for 15,555 patients, and 252 specialty doctors provided ED specialty consultations. Of the 742 doctors who used the mobile EMR, 208 doctors used it for the specialty consultation process. After excluding the cases lacking essential information, 21,885 consultations with 208 doctors were included for analysis. According to the mobile EMR usage pattern, the average usage frequency of all users was 13.3 logs/day, and the average duration of the completion of the specialty consultation was 51.7 minutes. There was a significant inverse relationship between the frequency of mobile EMR usage and time interval from ED request to consultation completion by specialty doctors (coefficient=–0.19; 95% CI –0.32 to –0.06; P=.005). Secondary analysis with the response time was done. There was also a significant inverse relationship between the frequency of specialty doctors’ mobile EMR usage and the response time to consultation requests (coefficient=–0.18; 95% CI –0.30 to –0.04; P=.009).

Conclusions

Our findings suggest that frequent mobile EMR usage is associated with quicker response time to ED consultation requests.
Optimizing Antihypertensive Medication Classification in Electronic Health Record-Based Data: Classification System Development and Methodological Comparison
Authors: McDonough Caitrin W , Smith Steven M , Cooper-DeHoff Rhonda M , Hogan William R
Published: December 2019

Background

Computable phenotypes have the ability to utilize data within the electronic health record (EHR) to identify patients with certain characteristics. Many computable phenotypes rely on multiple types of data within the EHR including prescription drug information. Hypertension (HTN)-related computable phenotypes are particularly dependent on the correct classification of antihypertensive prescription drug information, as well as corresponding diagnoses and blood pressure information.

Objective

This study aimed to create an antihypertensive drug classification system to be utilized with EHR-based data as part of HTN-related computable phenotypes.

Methods

We compared 4 different antihypertensive drug classification systems based off of 4 different methodologies and terminologies, including 3 RxNorm Concept Unique Identifier (RxCUI)–based classifications and 1 medication name–based classification. The RxCUI-based classifications utilized data from (1) the Drug Ontology, (2) the new Medication Reference Terminology, and (3) the Anatomical Therapeutic Chemical Classification System and DrugBank, whereas the medication name–based classification relied on antihypertensive drug names. Each classification system was applied to EHR-based prescription drug data from hypertensive patients in the OneFlorida Data Trust.

Results

There were 13,627 unique RxCUIs and 8025 unique medication names from the 13,879,046 prescriptions. We observed a broad overlap between the 4 methods, with 84.1% (691/822) to 95.3% (695/729) of terms overlapping pairwise between the different classification methods. Key differences arose from drug products with multiple dosage forms, drug products with an indication of benign prostatic hyperplasia, drug products that contain more than 1 ingredient (combination products), and terms within the classification systems corresponding to retired or obsolete RxCUIs.

Conclusions

In total, 2 antihypertensive drug classifications were constructed, one based on RxCUIs and one based on medication name, that can be used in future computable phenotypes that require antihypertensive drug classifications.
Impact of a Knowledge Translation Intervention on Physical Activity and Mobility in Older Adults (the Move4Age Study): Randomized Controlled Trial
Authors: Neil-Sztramko Sarah , Smith-Turchyn Jenna , Richardson Julie , Dobbins Maureen
Published: December 2019

Background

The McMaster Optimal Aging Portal (the Portal) was launched in 2014 as a knowledge translation (KT) tool to increase access to evidence-based health information.

Objective

The purpose of this study was to understand if and how dissemination of mobility information through the Portal impacts physical activity (PA) in older adults.

Methods

In this randomized controlled trial, participants (n=510) were assigned to a 12-week mobility-focused KT intervention or self-serve control group. The intervention included weekly email alerts and a study-specific social media hashtag linking to mobility-focused Portal materials. The control group was able to access the Portal on their own but did not receive targeted KT strategies. Participants completed questionnaires (including the Rapid Assessment of Physical Activity to quantify PA) at baseline, end of the study, and 3-month follow-up.

Results

Participants were predominantly female (430/510, 84.3%), mean age 64.7 years, with no baseline differences between groups. Over half (277/510, 54.3%) of the participants were classified as “active” at baseline. There was no significant between-group difference in the PA category. Overall, both groups increased their PA with improvements maintained at 3-month follow-up (P<.001). In planned subgroup analyses, the KT intervention had a significant effect for those with poor or fair baseline self-rated health (P=.03).

Conclusions

No differences were found between those who received the targeted intervention and a control group with self-serve access to the Portal, except in subgroups with low self-rated health. Both groups did report increases in PA that were sustained beyond participation in a research study. Findings suggest that different KT strategies may be needed for different types of users, with more intense interventions being most impactful for certain groups (ie, those with lower self-rated health).

Trial Registration

ClinicalTrials.gov NCT02947230; https://clinicaltrials.gov/ct2/show/NCT02947230
Wound Care Knowledge, Attitudes, and Practices and Mobile Health Technology Use in the Home Environment: Cross-Sectional Survey of Social Network Users
Authors: Kuan Ya-Ting , Wang Tze-Fang , Guo Chao-Yu , Tang Fu-In , Hou I-Ching
Published: December 2019

Background

Injury causing wounds is a frequent event. Inadequate or inappropriate treatment of injuries can threaten individual health. However, little is known about wound care knowledge, attitudes, and practices and mobile health (mHealth) use in the home environment in Taiwan.

Objective

This study aimed to evaluate wound care knowledge, attitudes, and practices and mHealth technology use among social network users.

Methods

A cross-sectional survey on social media platforms was conducted on adults aged 20 years and older. Data were collected from social network users in the home environment.

Results

A total of 361 participants were enrolled. The mHealth technology use of participants was positively correlated with wound care knowledge (r=.132, P=.01), attitudes (r=.239, P<.001), and practices (r=.132, P=.01). Participants did not have adequate knowledge (correct rate 69.1%) and were unfamiliar with the guidelines of proper wound care (correct rate 74.5%). Most participants had positive attitudes toward wound care and mHealth technology use. A total of 95.6% (345/361) of participants perceived that the use of mHealth technology can improve wound care outcomes, and 93.9% (339/361) perceived that wound care products should be optimized to be used with a mobile device. However, 93.6% (338/361) of participants had no experience using mHealth technology for wound care.

Conclusions

Our study shows the potential of mHealth technology to enhance wound care knowledge among social network users. Thus, government agencies and medical institutions in Taiwan should provide easy-to-use information products that enhance wound care knowledge, promote adequate behavior toward wound care, and prevent unpredictable or undesirable outcomes.
The Kids Obesity Prevention Program: Cluster Randomized Controlled Trial to Evaluate a Serious Game for the Prevention and Treatment of Childhood Obesity
Authors: Mack Isabelle , Reiband Nadine , Etges Carolin , Eichhorn Sabrina , Schaeffeler Norbert , Zurstiege Guido , Gawrilow Caterina , Weimer Katja , Peeraully Riyad , Teufel Martin , Blumenstock Gunnar , Giel Katrin Elisabeth , Junne Florian , Zipfel Stephan
Published: December 2019

Background

Health games provide opportunities for the treatment and prevention of childhood obesity. We developed a motion-controlled serious game for children that addresses 3 core topics of nutrition, physical activity, and stress coping. It is the first serious game that extensively targets the dietary energy density principle (DED-P) in relation to nutrition. The game is intended to provide an additional educational component for the prevention and treatment of obesity in children.

Objective

The Kids Obesity Prevention study aimed to evaluate the newly developed game and to evaluate how well children are able to understand and apply the DED-P.

Methods

This cluster randomized controlled trial collected data from 82 primary school children aged 9 to 12 years and their parents at baseline (T0), at 2 weeks after study commencement (T1), and at the 4-week follow-up (T2). The dropout rate was 3.6%. The intervention group (IG) played the game within 2 weeks (2 sessions with different game modules). One part of the game involves selection of food with the lower energy density when presented with a pair of foods. This allows assessment of whether the children have understood the DED-P and whether they can apply it to unknown foods under time pressure. The control group (CG) received a brochure about the food pyramid concept and physical activity. The primary outcome was the gain in knowledge (nutrition and stress coping) and measured with a pretested questionnaire. The secondary outcomes were the maintenance of knowledge, application of the DED-P, feelings during game play, game acceptance, and behavioral measures (physical activity, media consumption, and dietary intake).

Results

The knowledge score ranging from 0 to 100 increased from T0 (IG: 53 [SD 10], CG: 50 [SD 11]) to T1 (IG: 69 [SD 11], CG: 52 [SD 12]) in IG versus CG (P<.001). At T2, the knowledge score of IG remained at the same level as that of T1. Game data showed that after DED-P education, the classification under time pressure of unknown versus known food pairs according to their DED category was similar (hit rate around 70%). Overall, 95% of the children liked the game very much or much. No group changes were observed at the behavioral level.

Conclusions

The Kids Obesity Prevention program sustainably increased knowledge in the areas of nutrition and stress coping, and children were able to apply the DED-P.

Trial Registration

ClinicalTrials.gov NCT02551978; https://clinicaltrials.gov/ct2/show/NCT02551978
Use of Brief Messages Based on Behavior Change Techniques to Encourage Medication Adherence in People With Type 2 Diabetes: Developmental Studies
Authors: Bartlett Yvonne Kiera , Farmer Andrew , Rea Rustam , French David P
Published: December 2019

Background

Brief messages are a promising way to improve adherence to medication for people with type 2 diabetes. However, it is often unclear how messages have been developed and their precise content, making it difficult to ascertain why certain messages are successful and some are not.

Objective

The goal of the research was to develop messages that have proven fidelity to specified evidence-derived behavior change techniques (BCTs) and are acceptable to people with type 2 diabetes.

Methods

Four studies were conducted: (1) a workshop (n=21) where behavioral change researchers and health care professionals developed messages based on specific BCTs or beliefs or concerns related to taking medication, (2) a focus group study with people with type 2 diabetes (n=23) to assess acceptability of the approach, (3) a survey to ascertain the acceptability of a subset of messages to people with type 2 diabetes (n=61) and, (4) a survey with behavior change researchers to assess the fidelity of a subset of messages to their intended BCT (n=18).

Results

In study 1, 371 messages based on 38 BCTs and beliefs/concerns were developed. Workshop participants rated BCTs to be relevant to medication adherence (mean 7.12/10 [SD 1.55]) and messages to have good fidelity (mean 7.42/10 [SD 1.19]). In study 2, the approach of providing medication adherence support through text messages was found to be acceptable. In study 3, mean acceptability of all BCTs was found to be above the midpoint (mean 3.49/5 [SD 0.26]). In study 4, mean fidelity for all BCTs was found to be above the midpoint (mean 7.61/10 [SD 1.38]).

Conclusions

A library of brief messages acceptable to people with type 2 diabetes and representative of specific evidence-derived BCTs was developed. This approach allowed brief messages to be developed with known content that can be used to test theory.
Digital HIV Care Navigation for Young People Living With HIV in San Francisco, California: Feasibility and Acceptability Study
Authors: Trujillo Dillon , Turner Caitlin , Le Victory , Wilson Erin C , Arayasirikul Sean
Published: December 2019

Background

HIV continues to be a public health challenge adversely affecting youth and young adults, as they are the fastest-growing group of new HIV infections in the United States and the group with the poorest health outcomes among those living with HIV. HIV prevention science has turned to mobile health as a novel approach to reach and engage young people living with HIV (YPLWH) experiencing barriers to HIV care.

Objective

This study aimed to assess the feasibility and acceptability of a text message–based HIV care navigation intervention for YPLWH in San Francisco. Health eNavigation is a 6-month text message–based HIV care navigation where YPLWH are connected to their own HIV care navigator through text messaging to improve engagement in HIV primary care. Digital HIV care navigation included delivery of the following through SMS text messaging: (1) HIV care navigation, (2) health promotion and education, (3) motivational interviewing, and (4) social support.

Methods

We evaluated the feasibility and acceptability of a text message–based HIV care navigation intervention among YPLWH. We assessed feasibility using quantitative data for the overall sample (N=120) to describe participant text messaging activity during the intervention. Acceptability was assessed through semistructured, in-depth interviews with a subsample of 16 participants 12 months after enrollment. Interviews were audio-recorded, transcribed, and analyzed using grounded theory.

Results

Overall, the text message–based HIV care navigation intervention was feasible and acceptable. The majority of participants exhibited medium or high levels of engagement (50/120 [41.7%] and 26/120 [21.7%], respectively). Of the majority of participants who were newly diagnosed with HIV, 63% (24/38) had medium to high engagement. Similarly, among those who were not newly diagnosed, 63% (52/82) had medium to high engagement. The majority of participants found that the intervention added value to their lives and improved their engagement in HIV care, medication adherence, and viral suppression.

Conclusions

Text message–based HIV care navigation is a potentially powerful tool that may help bridge the gaps for linkage and retention and improve overall engagement in HIV care for many YPLWH. Our results indicate that participation in text message–based HIV care navigation is both feasible and acceptable across pervasive structural barriers that would otherwise hinder intervention engagement.
Cancer Patients’ and Survivors’ Perceptions of the Calm App: Cross-Sectional Descriptive Study
Authors: Huberty Jennifer , Puzia Megan , Eckert Ryan , Larkey Linda
Published: December 2019

Background

There is a need for tools to decrease cancer patients’ and survivors’ long-term symptom burden. Complementary strategies, such as meditation, can accompany pharmacologic therapy to improve symptoms. Although support programs with targeted content have wider reach, higher adherence, and greater impact, there are no consumer-based meditation apps designed specifically for cancer.

Objective

This study aimed to gather information to advise the development of a cancer-specific meditation app in a small convenience sample of cancer patients and survivors who currently use the Calm app.

Methods

Adult cancer patients and survivors who are Calm users (N=82) were recruited through the Daily Calm Facebook page. Participants completed a Web-based survey related to Calm app use and satisfaction, interest in and ideas for a cancer-specific Calm app, and demographic characteristics. Open-ended responses were inductively coded.

Results

Participants were aged between 18 and 72 years (mean 48.60 years, SD 15.20), mostly female (77/82, 94%), white (65/79, 82%), and non-Hispanic (70/75, 93%), and reported using Calm at least 5 times per week (49/82, 60%). Although rates of satisfaction with current Calm components were high (between 65/82, 79% and 51/81, 63%), only 49% (40/82) of participants used guided meditations that they felt specifically helped with their cancer-related symptoms and survivorship, and 40% (33/82) would prefer more cancer-related content, with guided meditations for cancer-specific anxieties (eg, fear of recurrence; n=15) and coping with strong emotions (n=12) being the most common suggestions. A majority of participants (51/82, 62%) reported that they would be interested in becoming a member of a Calm cancer community (eg, in-app discussion boards: 41/46, 89%; and social media communities: 35/42, 83%). Almost half of the participants (37/82, 45%) reported that they would benefit from features that tracked symptoms in concurrence with app usage, but respondents were divided on whether this information should be shared with health care providers through the app (49/82, 60% would share).

Conclusions

Responses suggest ways in which the current Calm app could be adapted to better fit cancer patients’ and survivors’ needs and preferences, including adding cancer-specific content, increasing the amount of content focusing on coping with strong emotions, developing communities for Calm users who are cancer patients and survivors, and including features that track cancer-related symptoms. Given differences in opinions about which features were desirable or would be useful, there is a clear need for future cancer-specific apps to be customizable (eg, ability to turn different features on or off). Although future research should address these topics in larger, more diverse samples, these data will serve as a starting point for the development of cancer-specific meditation apps and provide a framework for evaluating their effects.
Challenges in Acceptance and Compliance in Digital Health Assessments During Pregnancy: Prospective Cohort Study (Preprint)
Authors: Brusniak Katharina , Arndt Hannah Maria , Feisst Manuel , Haßdenteufel Kathrin , Matthies Lina Maria , Deutsch Thomas Maximilian , Hudalla Hannes , Abele Harald , Wallwiener Markus , Wallwiener Stephanie
Published: December 2019

BACKGROUND

Pregnant women are increasingly using mobile apps to access health information during the antenatal period. Therefore, digital health solutions can potentially be used as monitoring instruments during pregnancy. However, a main factor of success is high user engagement.

OBJECTIVE

The aim of this study was to analyze engagement and factors influencing compliance in a longitudinal study targeting pregnant women using a digital health app with self-tracking.

METHODS

Digitally collected data concerning demographics, medical history, technical aspects, and mental health from 585 pregnant women were analyzed. Patients filling out ≥80% of items at every study visit were considered to be highly compliant. Factors associated with high compliance were identified using logistic regression. The effect of a change in mental and physical well-being on compliance was assessed using a one-sample t test.

RESULTS

Only 25% of patients could be considered compliant. Overall, 63% left at least one visit blank. Influential variables for higher engagement included higher education, higher income, private health insurance, nonsmoking, and German origin. There was no relationship between a change in the number of physical complaints or depressive symptoms and study dropout.

CONCLUSIONS

Maintaining high engagement with digital monitoring devices over a long time remains challenging. As cultural and socioeconomic background factors had the strongest influence, more effort needs to be directed toward understanding the needs of patients from different demographic backgrounds to ensure high-quality care for all patients. More studies need to report on compliance to disclose potential demographic bias.
Overview of Digital Health Research: A Global Multi-Disciplinary Collaborative Alliance from the Worldwide Universities Network (Preprint)
Authors: Poon Simon , Latt Mark , Morris Michelle A , Johnson Owen , Fuggle Nicholas , Duan Zhiyao , Lee Allen , Oldroyd Rachel , Penm Jonathan , Lin Bryant , Zand Martin , Hur Chin , Wyatt Jeremy , Tsoi Kelvin
Published: December 2019

BACKGROUND

Digital health is an important part of the future of health care, prevention and management of disease and innovative monitoring solutions. With an aging population and rising health related costs, digital health is an essential part of the solution, alongside the emerging big data and associated analytics. To varying extents, digital health and big data are present worldwide. However, consistency in terminology, regulation and implementation differ. As an international network of interdisciplinary experts we review and discuss the digital health and big data landscape.

OBJECTIVE

We firstly identify current challenges and solutions in digital health development, research, deployment in the management of non-communicable disease and regulation and then go on to establish an ongoing and international collaboration of multidisciplinary researchers and educators; creating opportunities for research and education.

METHODS

The Digital Health Research Network was established using the Worldwide Universities Network as a platform and a funding resource. The newly formed network harnesses expertise from a wide array of academic disciplines within applications of digital health and big data for health.
Meetings took place both electronically and face to face, with a Research Open Day in Sydney and the International Symposium for Digital Health in Hong Kong facilitating wider networking and discussion.

RESULTS

Many challenges working across disciplines in the digital health area have been identified. These include inconsistent definitions for digital health and big data, a diverse range of digital technologies available across the globe, differences in regulation of such technologies. There is not equity in resources and standards globally. He range of stakeholders involved in digital health and big data relating to health are extensive. It is important that these stakeholders can communicate effectively, with a common technical language. Continued development, education and widening engagement are integral components of developing digital health worldwide.

CONCLUSIONS

Digital Health is a necessary and sufficient factor in achieving health gains. However, in is critical that digital health is leveraged appropriately and that transformation of interdisciplinary practices can intelligently link digital health with care management processes to make a difference. The new interdisciplinary, International Society for Digital Health aims to provide a platform to facilitate this.

CLINICALTRIAL

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The Postencounter Form System: Viewpoint on Efficient Data Collection Within Electronic Health Records (Preprint)
Authors: Held Philip , Boley Randy A , Faig Walter G , O'Toole John A , Desai Imran , Zalta Alyson K , Khan Jawad , Sims Shannon , Brennan Michael B , Van Horn Rebecca , Glover Angela C , Hota Bala N , Patty Brian D , Rab S Shafiq , Pollack Mark H , Karnik Niranjan S
Published: December 2019

UNSTRUCTURED

Electronic health records (EHRs) offer opportunities for research and improvements in patient care. However, challenges exist in using data from EHRs due to the volume of information existing within clinical notes, which can be labor intensive and costly to transform into usable data with existing strategies. This case report details the collaborative development and implementation of the postencounter form (PEF) system into the EHR at the Road Home Program at Rush University Medical Center in Chicago, IL to address these concerns with limited burden to clinical workflows. The PEF system proved to be an effective tool with over 98% of all clinical encounters including a completed PEF within 5 months of implementation. In addition, the system has generated over 325,188 unique, readily-accessible data points in under 4 years of use. The PEF system has since been deployed to other settings demonstrating that the system may have broader clinical utility.
THE FACTORS WHICH INFLUENCE THE RELATIONSHIP BETWEEN A NETWORK’S SYNERGIZING CAPABILITY AND THE INCREASE IN A SALESPERSON’S PERFORMANCE
Authors: Bagus Nyoman Udayana Ida , Farida Naili
Published: December 2019

Introduction: This research aims to explore the concept of customer networks in the context of sales. A research model is proposed to explain how a salesperson’s performance is increased by synergizing the network. Background Problems: There are inconsistent research findings on the relationship between adaptive selling and salespeople’s performance. The proposed research question is whether adaptive selling has an effect on a salesperson’s performance through his/her customer networking capability or not? Novelty: the novelty of this research is the analysis of the capabilities of customer networking, based on information sharing, promotion sharing, and knowledge sharing. Research Methods: This research involved 266 salespeople from the soft drinks’ industry. The hypotheses were tested using structural equation modeling. Findings: The results of the study show that adaptive selling is able to increase a salesperson’s performance through their customer networking capability. The customer’s order quality, adaptive selling and communication quality have significant positive effects on the capability of the customer network. Furthermore, the customer’s order quality, retention, and communication quality have significant positive impacts on the salesperson’s performance. The variable which has the most influence on the increase in the salesperson’s performance is communication quality. Conclusion: This study concludes that the ability of the customer networking capability to link between adaptive selling and the salesperson’s performance is real. Additionally, the quality of the customer’s orders, retention and the quality of their communications give significant positive effects to a salesperson’s performance. Therefore, companies should pay special attention to the salespeople who perform best, particularly those who can broaden new networking customers.
MANAGING BRANDS’ POPULARITY ON FACEBOOK: POST TIME, CONTENT, AND BRAND COMMUNICATION STRATEGIES
Authors: Hanifawati Tri , Ritonga Utan Sahiro , Puspitasari Euis Evi
Published: December 2019

Introduction: A brand’s popularity on social media affects its customers’ purchasing intention and purchasing decision. Background Problem: A review of the literature shows that a brand’s popularity on social media has a secure connection with its content and the time information about it is posted; allegedly the brand’s interactions are also influential. Indicators of its popularity include the number of likes, shares, comments, and views for it. Novelty: Previous brand popularity studies were limited to the features of likes, comments, and shares as a function of the content and time, and OLS was commonly used. However, this study adds the views feature and the function of the administrator’s comments to complete the gap. GLS is used as the method of analysis. Research Method: Data are collected through the observation of six top international food and beverage products’ categories on the Facebook fan page. The data were analyzed using the Seemingly Unrelated Regression (SUR), and the Mann-Whitney and Kruskal-Wallis methods. Findings: The study’s findings shows that video and the day to post have a significant influence and increase the number of likes, shares, comments, and views. A caption only shows significance to increase the number of likes and shares. The hour has a significant effect on comments and shares. The time of posting indicates that posting on weekdays and during busy periods is more effective for increasing the popularity of brands. The administrator’s comments significantly influence the increase in the number of comments and views, while two-way communication is more significant for increasing a brand’s popularity. Conclusion: These findings provide a deeper insight to help managers to improve their brand’s popularity on social media by exploring how brands manage their fan pages.
IN VITRO STUDIES ON THE ANTIDIABETIC ACTIVITY OF 2-THIOHYDANTOIN USING α-amylase AND α-GLUCOSIDASE
Authors: UMA S  , DEVIKA PT
Published: December 2019

Objective: The aim of the present study was to investigate the inhibitory effect of 2-thiohydantoin on the enzymes α-amylase and α-glucosidase in vitro as an antidiabetic therapeutic approach to reduce gastrointestinal glucose production.

Methods: Antidiabetic activity of the compound, 2-thiohydantoin was measured using the enzymes α-amylase and α-glucosidase.

Results: Half-maximal inhibitory concentration of the antidiabetic α-amylase was found to be 410.35 μg/ml and α-glucosidase was found to be 356.33 μg/ml, respectively.

Conclusion: The result obtained in the in vitro enzyme assay suggests the antidiabetic activity of 2-thiohydantoin.