bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Guru Dalam Menanamkan Sikap Toleransi Pada Siswa Dalam Menanggapi Perbedaan Keyakinan
Authors: Khairin Nisa Ummu , Wardan Khusnul
Published: January 2025

Toleransi merupakan sikap menghargai segala perbedaan yang ada demi terciptanya lingkungan yang rukun dan harmonis. Sekolah menjadi tempat berkumpulnya siswa dengan banyaknya perbedaan antara siswa satu dengan yang lainnya. Sehingga sikap toleransi menjadi penting ditanamkan pada diri peserta didik, hal ini tentu tidak lepas dari strategi guru dalam menanamkan sikap toleransi tersebut dilingkungan sekolah ataupun kelas. Tujuan penelitian ini adalah untuk menjawab pertanyaan penelitian terkait strategi guru dalam menanamkan sikap toleransi kepada siswa dalam menanggapi perbedaan keyakinan. Metode penelitian yang digunakan adalah metode library research. Teknik pengumpulan data menggunakan teknik dokumentasi yaitu, mencari dari berbagai sumber ilmiah di perpustakaan online maupun offline mulai dari buku, jurnal, catatan, majalah, dan laporan hasil penelitian terdahulu. Kemudian data yang terkumpul dianalisis. Hasil penelitian menunjukkan bahwa strategi yang guru lakukan dalam menanamkan sikap toleransi kepada siswa yang berbeda keyakinan ialah, mengenalkan perbedaan dan sikap toleransi, memberi motivasi, mengatur posisi duduk, membagi tempat ibadah siswa yang berbeda keyakinan, dan melakukan pendekatan kontribusi pembelajaran, guru menjadi role model, membagi kelompok belajar dengan siswa yang berbeda, serta memanfaatkan media pembelajaran yang edukatif bagi siswa.
Tolerance is an attitude of respecting all existing differences in order to create a peaceful and harmonious environment. Schools become a gathering place for students with many differences between one student and another. Thus, the attitude of tolerance becomes important to instill in students, which is certainly not separate from the teacher's strategy in instilling that attitude of tolerance within the school or classroom environment. The purpose of this research is to answer the research question regarding the teacher's strategies in instilling a sense of tolerance in students when responding to differences in beliefs. The research method used is the library research method. The data collection technique employs documentation techniques, which involve searching various scientific sources in both online and offline libraries, including books, journals, notes, magazines, and reports of previous research. Then the collected data is analyzed. The research results show that the strategies employed by teachers to instill a sense of tolerance in students of different beliefs include introducing differences and attitudes of tolerance, providing motivation, arranging seating positions, dividing worship places for students of different beliefs, and implementing a contribution-based learning approach, where teachers become role models, dividing study groups with students of different beliefs, and utilizing educational learning media for students.
Pengaruh Penerapan Program Mengaji Terhadap Kelancaran Membaca Al-Qur’an Siswa di SMA Plus Mlati Samarinda
Authors: Haryanti Yuyun , Afandi Nur Kholik
Published: January 2025

Penelitian ini bertujuan untuk mengkaji pengaruh penerapan program mengaji terhadap peningkatan kemampuan membaca Al-Qur'an siswa di SMA Plus Melati Samarinda. Melalui pendekatan kualitatif deskriptif, penelitian ini menganalisis data yang diperoleh dari wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa program mengaji yang dilaksanakan secara rutin telah memberikan dampak positif terhadap peningkatan kemampuan membaca Al-Qur'an siswa. Faktor-faktor yang mendukung keberhasilan program ini antara lain motivasi siswa, dukungan guru, dan metode pengajaran yang efektif. Meskipun demikian, masih terdapat beberapa kendala yang perlu diatasi, seperti kurangnya minat beberapa siswa dan keterbatasan fasilitas. Secara keseluruhan, program mengaji ini telah berkontribusi dalam membentuk karakter siswa yang religius dan berakhlak mulia. Penelitian ini merekomendasikan agar program serupa dapat diterapkan di sekolah-sekolah lain sebagai upaya meningkatkan kualitas pendidikan agama siswa.
This study aims to examine the effect of implementing a Quranic recitation program on improving students' ability to read the Quran at SMA Plus Melati Samarinda. Using a qualitative descriptive approach, this study analyzes data obtained from interviews, observations, and documentation. The results of the study show that the regular implementation of the Quranic recitation program has had a positive impact on improving students' ability to read the Quran. Factors supporting the success of this program include student motivation, teacher support, and effective teaching methods. However, there are still some obstacles that need to be overcome, such as a lack of interest from some students and limited facilities. Overall, the Quranic recitation program has contributed to shaping students' characters to be religious and have noble morals. This study recommends that similar programs can be implemented in other schools as an effort to improve the quality of students' religious education.
Pemanfaatan Media Youtube dalam Pembelajaran Pendidikan Agama Islam
Authors: Ahadi Abdi , Wardan Khusnul
Published: January 2025

Pemanfaatan media YouTube dalam pembelajaran Pendidikan Agama Islam (PAI) telah menjadi alternatif yang efektif untuk meningkatkan pemahaman siswa. YouTube menawarkan berbagai konten edukatif yang dapat diakses dengan mudah dan fleksibel. Penelitian ini bertujuan untuk menganalisis dampak penggunaan YouTube dalam proses pembelajaran PAI, terutama dalam aspek penguatan materi dan peningkatan motivasi siswa. Metode yang digunakan adalah studi literatur dengan pengumpulan data dari berbagai sumber yang relevan. Hasil penelitian menunjukkan bahwa video pembelajaran di YouTube mampu menghadirkan materi PAI secara menarik melalui visualisasi yang interaktif. Siswa dapat belajar secara mandiri, mengeksplorasi berbagai sudut pandang, dan mendiskusikan materi dengan lebih aktif. Selain itu, penggunaan YouTube juga membantu guru dalam menyampaikan materi yang kompleks dengan cara yang lebih sederhana dan menarik. Namun, tantangan dalam penggunaan YouTube, seperti pemilihan konten yang sesuai dan kontrol terhadap informasi yang diterima siswa, perlu diperhatikan. Secara keseluruhan, YouTube berpotensi menjadi media pembelajaran yang efektif dalam PAI, mendukung pembelajaran yang lebih dinamis dan menarik bagi generasi digital saat ini. Penelitian ini diharapkan dapat memberikan wawasan bagi pendidik dalam mengintegrasikan teknologi dalam pembelajaran PAI.
The use of YouTube media in Islamic Religious Education (PAI) learning has become an effective alternative to improve student understanding. YouTube offers a variety of educational content that can be accessed easily and flexibly. This study aims to analyze the impact of using YouTube in the PAI learning process, especially in terms of material reinforcement and increasing student motivation. The method used is a literature study with data collection from various relevant sources. The results of the study indicate that learning videos on YouTube are able to present PAI material in an interesting way through interactive visualization. Students can learn independently, explore various points of view, and discuss the material more actively. In addition, the use of YouTube also helps teachers in delivering complex material in a simpler and more interesting way. However, challenges in using YouTube, such as selecting appropriate content and controlling the information received by students, need to be considered. Overall, YouTube has the potential to be an effective learning medium in PAI, supporting more dynamic and interesting learning for today's digital generation. This study is expected to provide insight for educators in integrating technology in PAI learning
Isu-Isu Global Pendidikan: Tantangan Globalisasi dan Modernisasi
Authors: Soe’aiddy Mochammad Deddy , Palah
Published: January 2025

Penelitian ini dilatarbelakangi oleh kenyataan bahwa diantara isu global yang berimplikasi terhadap pendidikan adalah isu revolusi industri 4.0 sebagai fenomena abad 21, era digitalisasi akibat revolusi industri 4.0 yang telah memasuki sendi-sendi kehidupan, sehingga eksistensi setiap orang perlu terus beradaptasi agar terciptanya efektivitas dan efisiensi kinerja. Dalam lingkungan makro, dunia telah memasuki era disrupsi. Yaitu disrupsi pada tatanan sosial yang disebabkan oleh kemajuan teknologi. Jenis penelitian ini adalah penelitian kepustakaan. Hasil penelitian ini menunjukkan bahwa isu global pendidikan yang saat ini masih sering diperbincangkan adalah dampak revolusi industri 4.0, era disrupsi dan kurikulum abad 21 yang sangat berimplikasi terhadap dunia pendidikan. Rumusan yang paling penting agar manusia mampu bersaing di tingkat global adalah proses pendidikan harus berorientasi pada pemenuhan keseimbangan antara pengetahuan, keterampilan, karakter dan metakognisi, keempat orientasi tersebut juga harus terus ditingkatkan dalam proses pembelajaran baik formal, nonformal, maupun informal.
This research is motivated by the fact that among global issues that have implications for education are the issue of the industrial revolution 4.0 as a 21st century phenomenon, the era of digitalization due to the industrial revolution 4.0 which has entered the joints of life, so that the existence of everyone needs to continue to adapt in order to create effectiveness and efficiency of performance. . In the macro environment, the world has entered an era of disruption. Namely disruption in the social order caused by technological advances. This type of research is library research. The results of this study show that the global issue of education that is currently still often discussed is the impact of the industrial revolution 4.0, the era of disruption and the 21st century curriculum which has very implications for the world of education. The most important formulation so that humans are able to compete at a global level is that the educational process must be oriented towards fulfilling the balance between knowledge, skills, character and metacognition, the four orientations must also continue to be improved in the learning process, both formal, non-formal, and informal.
Pemikiran Pendidikan Pesantren KH.Hasyim Asy’ari dan Relevansinya Terhadap Pengembangan Pendidikan Islam di Indonesia
Authors: Suhartini  , Wardan Khusnul
Published: January 2025

Penelitian ini mengkaji pemikiran pendidikan pesantren KH.Hasyim Asy’ari dan relevansinya terhadap pengembangan pendidikan islam di Indonesia. dengan menggunakan metode penelitian perpustakaan dan analisis deskriktif-interprektif, studi ini mengungkapkan konsep pendidikan pesantren yang dikembangkan oleh KH.Hasyim Asy’ari serta kontribusinya dalam membentuk karakter pendidikan islam diIndonesia. Hasil penelitian menunjukkan bahwa pemikiran KH.Hasyim Asy’ari yang menekankan pada interaksi ilmu agama dan umum, pembentukan akhlak, serta mengembangkan keterampilan hidup masih sangat relevan dalam konteks pendidikan islam kontenporer diIndonesia.
Peran Orang Tua dalam Mendukung Kemajuan Akademik di Era Modern
Authors: Ahadi Abdi , Afandi Nur Kholik
Published: January 2025

Penelitian ini mengkaji peran orang tua dalam mendukung prestasi akademik anak di era modern dengan menggunakan metode Systematic Literature Review (SLR). Orang tua berperan penting sebagai mentor, motivator, dan penyedia sumber daya untuk membantu anak belajar, meskipun anak sudah menerima pendidikan formal di sekolah. Hasil penelitian menunjukkan bahwa keterlibatan orang tua di rumah, seperti membantu mengerjakan tugas sekolah dan menyediakan fasilitas belajar, memiliki dampak signifikan terhadap prestasi akademik anak. Selain itu, kerja sama antara orang tua dan sekolah juga sangat penting untuk menciptakan lingkungan belajar yang mendukung keberhasilan akademik. Penelitian ini memberikan wawasan mengenai pentingnya keterlibatan orang tua dalam pendidikan anak dan menyoroti bentuk-bentuk keterlibatan yang efektif untuk meningkatkan hasil belajar. Temuan ini menekankan bahwa kualitas keterlibatan orang tua lebih penting dibandingkan dengan frekuensinya. Dukungan yang berkelanjutan dan komunikasi yang baik antara orang tua, anak, dan guru menjadi faktor kunci dalam menciptakan suasana belajar yang positif dan produktif di rumah maupun di sekolah.
This study explores the role of parents in supporting children's academic success in the modern era using the Systematic Literature Review (SLR) method. Parents play a vital role as mentors, motivators, and providers of resources to help their children learn, even while attending formal schooling. The findings show that parental involvement at home, such as helping with homework and providing learning resources, significantly impacts children's academic performance. Furthermore, collaboration between parents and schools is crucial in creating a supportive learning environment for academic success. This study provides insights into the importance of parental involvement in children's education and highlights effective forms of engagement to enhance learning outcomes. The findings emphasize that the quality of parental involvement is more important than the frequency. Consistent support and good communication between parents, children, and teachers are also key factors in creating a positive and productive learning atmosphere at home and school.
Pergeseran Konsepsi Kuburan Pada Masyarakat Hindu Bali: Antara Tantra, Calon Arang, dan Wacana Populer
Authors: Wirawan Komang Indra
Published: January 2025

The charnel ground (sĕma/setra) is one of the locations regarded as sacred by the Balinese Hindu community, serving as a center for various religious rituals, ranging from Pitra Yadnya to less common rites such as Ngĕreh. This sacredness is illustrated in the Calon Arang performance, where the charnel ground is featured as one of the key spaces, in addition to being a significant element in the Calon Arang text. On the other hand, various media, from films to information found on the internet, often depict charnel grounds in a negative context. Observing these two contrasting portrayals, this research is aimed at investigating the differences in perception regarding the meaning of charnel grounds from the two aforementioned perspectives, focusing on the discourses surrounding charnel grounds in Calon Arang (both in the text and in performance contexts) and comparing them with narratives disseminated through popular media, while analyzing these through the lens of Balinese Hindu theology rooted in Tantric teachings. The research method employed is a semiotic approach with a descriptive qualitative framework. The findings reveal that contemporary Balinese Hindus tend to hold a negative image of charnel grounds, which is inconsistent with the theological teachings of Hinduism. This shift in perception is largely influenced by widespread information from various popular media, such as social media and the internet, which often portray charnel grounds negatively. As a result, there is a dissonance between the values taught in the Śāstra and the general public's views. Understanding this shift becomes crucial in preserving the theological values of Hinduism amid the flow of digital information. Hence, this study highlights the urgency of awareness regarding this perceptual change and the need for concrete actions to uphold the integrity of religion and culture in Bali.
Overcoming challenges to integration of oral health into geriatric primary care
Authors: Varela Alberto Enrique , Baluchi Donna , Farrell Timothy W. , Rodríguez José E.
Published: January 2025

The Age-Friendly Health System movement has been a unifying factor in caring for older adults at the University of Utah Health. Despite progress, challenges to efficient healthcare collaboration exist, particularly between geriatric primary care and oral health. This manuscript presents four of those challenges (lack of communication between medical and dental providers, the distance between medical and dental services, patient discomfort with the inclusion of oral health in primary health care, and provider discomfort in requesting oral health information in medical encounters) with the solutions derived at the University of Utah Health. Leaders at University of Utah Health developed five interventions to address these challenges (participation in the development of EPIC Wisdom©, a fully integrated oral health record in the electronic health record (EHR), co-location in new centers and oral health consultation in existing centers, implementing a geriatric health assessment that included oral health, widespread adoption of the 4 Ms framework). Applying the lessons learned from these challenges can benefit all older adults and may help prevent the conditions associated with periodontal disease.
Análisis del error del posicionamiento satelital GALILEO en redes geodésicas locales. Caso de estudio: Rumiñahui-Ecuador
Authors:   Instituto Superior Tecnológico Superarse, Enríquez Hidalgo Dennys , Andrade William ,   Instituto Superior Tecnológico Superarse, Lala Lala Jorge ,   Instituto Superior Tecnológico Superarse
Published: January 2025

El presente estudio se centró en el análisis del error del posicionamiento satelital GALILEO en redes geodésicas locales, con un enfoque específico en el cantón Rumiñahui, Ecuador. El objetivo principal fue comparar las coordenadas determinadas con el sistema satelital europeo con las obtenidas por medio de una red geodésica GPS. Para llevar a cabo esta investigación, se rastrearon cinco puntos de la red geodésica utilizando equipos GNSS multi-constelación y multifrecuencia, realizando sesiones independientes de hasta 8 horas. Además, se enlazó a la Red GNSS de Monitoreo Continuo del Ecuador – REGME por medio de 2 EMC. Los datos recopilados se procesaron en un software comercial y posteriormente se calculó el error cuadrático medio entre coordenadas GPS y GALILEO. Los resultados indicaron que el RMSE entre las dos redes fue de 4.3 centímetros, este valor sugiere que el sistema Galileo ofrece una precisión adecuada para aplicaciones de ingeniería como el catastro, topografía o fotogrametría. Del estudio se concluye que, la implementación de redes geodésicas utilizando el sistema Galileo es viable para proyectos que posean los requisitos mencionados. Se recomienda replicar esta metodología en diferentes ubicaciones a lo largo del país, con el objeto de validar la precisión del sistema europeo en todas las regiones del Ecuador, y asegurar su aplicabilidad en diversos contextos geográficos.
Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage
Authors: Pellegrino Raffaele , Gravina Antonietta Gerarda
Published: January 2025

The recent study published in the World Journal of Gastroenterology examines the interplay among the neuroendocrine axis, gut microbiota, inflammatory markers, and gastrointestinal symptoms in irritable bowel syndrome (IBS). By integrating all these factors into a single study, this approach reflects the modern concept of functional gastrointestinal disorders as disorders of the gut-brain interaction to be approached in a multiparametric manner, also incorporating non-gastroenterological elements and extending evaluations to parameters related to the neuroendocrine axis. This invited letter to the editor summarizes the main results of the aforementioned study and highlights its multiparametric approach, including variables not strictly gastroenterological, in the study of IBS, and discusses its strengths and limitations.
Ras-related protein Rab24 plays a predictive role in hepatocellular carcinoma and enhanced tumor proliferation
Authors: Ding Han , Ding Zhi-Guo , Liu Song , Mao Xu-Nan , Lu Xing-Sheng
Published: January 2025

BACKGROUND

Ras-related protein Rab24, which belongs to the small GTPase family, plays a crucial role in regulating intracellular protein trafficking. Dysregulation of Rab24 has been recently identified in hepatocellular carcinoma (HCC). However, its clinical significance and tumor related effects remain to be further clarified.

AIM

To explore the expression pattern of Rab24 and its role in HCC progression.

METHODS

The expression profile of Rab24 was tested in HCC tissues together with adjacent tissues from transcriptional, mRNA, and protein levels. The prognostic role of Rab24 in HCC was assessed by univariate and multivariate analyses. Clinical outcomes were evaluated by the Kaplan-Meier analysis and log-rank test. The effect of Rab24 on cell proliferation was tested through cellular experiments and xenograft experiments.

RESULTS

Rab24 expression was elevated in HCC tissues compared to adjacent liver tissues. High expression of Rab24 was significantly associated with larger tumor size and advanced tumor stage. Moreover, HCC patients with high Rab24 expression showed poorer overall survival, and Rab24 was identified as an independent prognosis factor according to multivariate analysis. By using overexpression and shRNA knockdown strategies in HCC cell lines, we found that Rab24 can promote HCC proliferation. Finally, we validated that silencing Rab24 significantly attenuated xenograft growth in vivo .

CONCLUSION

Our study demonstrated that high expression of Rab24 was significantly correlated with poorer prognosis of HCC patients, indicating the potential of Rab24 as a novel clinical biomarker and therapeutic target.
Role of Helicobacter pylori infection and the risk of cholelithiasis
Authors: Fabbri Nicolò , Greco Salvatore , Pesce Antonio , Virgilio Francesco , Romeo Danila , Feo Carlo V
Published: January 2025

This article aims to deepen the understanding of the role of Helicobacter pylori (H. pylori ) infection in the development of cholelithiasis, initiated by the article by Yao et al , who investigated the potential link between H. pylori infection and the development of cholelithiasis through a multicenter retrospective study on an Asian population of over 70000 participants. They also performed a comprehensive analysis of previously published studies on H. pylori and cholelithiasis, finding a positive association therein [odds ratio (OR) = 1.103, P = 0.049]. Patients positive for H. pylori also had lower levels of total and direct bilirubin, but higher levels of total cholesterol and low-density lipoprotein cholesterol compared to uninfected patients (P < 0.05). Cohort studies have confirmed that H. pylori is a risk factor for cholelithiasis (P < 0.0001), and aggregate analyses of case-control and cross-sectional studies have shown a positive association between H. pylori and cholelithiasis in Asia (OR = 1.599, P = 0.034), but not in Europe (OR = 1.277, P = 0.246). Moreover, H. pylori appears to be related to a higher ratio of choledocholithiasis/cholecystolithiasis (OR = 3.321, P = 0.033). The authors conclude that H. pylori infection is positively correlated with cholelithiasis, particularly with the choledocholithiasis phenotype, especially in Asia, and it is potentially related to bilirubin and cholesterol metabolism.
Mind the gut: Navigating the complex landscape of gastroprotection in neurosurgical patients
Authors: Venkatesan Subeikshanan , Lucke-Wold Brandon
Published: January 2025

Neurosurgical patients, including those with severe traumatic brain injury, spinal cord injury, stroke, or raised intracranial pressure, are at heightened risk for stress ulcers and aspiration pneumonitis, leading to significant morbidity and mortality. These patients are typically managed through both pharmacological interventions [e.g. , proton pump inhibitors (PPIs), histamine 2 (H2) antagonists, sucralfate] and non-pharmacological measures (e.g. , nasogastric decompression, patient positioning) to mitigate adverse outcomes. The pathogenesis of stress ulcers in neurosurgical patients is multifactorial, but the routine use of stress ulcer prophylaxis remains controversial. While gastric acid suppression with H2 receptor antagonists and PPIs is commonly employed, concerns have arisen regarding the association between elevated gastric pH, bacterial colonization, and ventilator-associated pneumonia. The lack of comprehensive data on gastroprotection in critically ill neurosurgical patients, who face a greater risk than non-neurosurgical counterparts, further complicates this issue. Recent studies, such as one by Gao et al on the efficacy of vonoprazan-amoxicillin dual therapy in elderly patients, highlight the potential of novel therapies, but the influence of pre-existing conditions like Helicobacter pylori infection remains unclear. Non-pharmacological interventions, including nasogastric decompression and early enteral nutrition, are critical in improving outcomes but require further research to refine strategies. This editorial underscores the need for tailored approaches and encourages further investigation into optimal gastroprotective strategies for neurosurgical patients.
Carbapenem-resistant Klebsiella pneumoniae infections after liver transplantation: Drug resistance, risk factors and impact on prognosis
Authors: Liu Tao-Hua , Chen Li-Hua , Wan Qi-Quan
Published: January 2025

BACKGROUND

Liver transplant (LT) recipients are susceptible to carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. Comprehensive research addressing the incidence, timing, infection sites, resistance patterns, treatment options, and associated risk factors among LT recipients with CRKP is now lacking.

AIM

To assess the incidence, resistance, therapy, and risk factors of CRKP infections post-LT, and to evaluate the impact of them on prognosis.

METHODS

A retrospective study was conducted, including 430 consecutive patients who underwent LT between January 2015 and June 2023. This study aimed to investigate the risk factors for CRKP infections and their influence on outcomes using logistic regression analysis.

RESULTS

Among the 430 patients who underwent LT, 20 (4.7%) experienced at least one documented CRKP infection within 3 months post-transplantation. The median time from LT to the onset of CRKP infections was 6.5 days. The lungs and bloodstream were the most common sites of CRKP infections. CRKP isolates were relatively susceptible to ceftazidime/avibactam (93.7%), polymyxin B (90.6%), and tigecycline (75.0%) treatment. However, all isolates were resistant to piperacillin/tazobactam, ceftazidime, cefepime, aztreonam, meropenem, and levofloxacin treatment. Recipients with CRKP infections had a mortality rate of 35%, the rate was 12.5% for those receiving ceftazidime/avibactam therapy. Multivariate analysis identified female sex [odds ratio (OR) = 3.306; 95% confidence interval (CI): 1.239-8.822; P = 0.017], intraoperative bleeding ≥ 3000 mL (OR = 3.269; 95%CI: 1.018-10.490; P = 0.047), alanine aminotransferase on day 1 post-LT ≥ 1500 U/L (OR = 4.370; 95%CI: 1.686-11.326; P = 0.002), and post-LT mechanical ventilation (OR = 2.772; 95%CI: 1.077-7.135; P = 0.035) as significant variables associated with CRKP. CRKP infections were related to an intensive care unit length (ICU) of stay ≥ 7 days and 6-month all-cause mortality post-LT.

CONCLUSION

CRKP infections were frequent complications following LT, with poor associated outcomes. Risk factors for post-LT CRKP infections included female sex, significant intraoperative bleeding, elevated alanine aminotransferase levels, and the need for mechanical ventilation. CRKP infections negatively impacted survival and led to prolonged ICU stays.
Sclerotherapy for hemorrhoidal disease: Recent evolutions of an oldies goldy
Authors: Gravante Gianpiero
Published: January 2025

Treatments for low degree hemorrhoids (I-III degree) are numerous and so are their counterparts for higher degrees. These treatments present nebulous differences in terms of indications and outcomes among techniques. Methods previously abandoned due to side effects and long-term results have recently rejoined the mainstream due to recent peculiar modifications: Hemorrhoidal sclerotherapy is enjoying a new age of interest due to the use of the foam form of polidocanol, which is more effective than the liquid one. Various articles have already shown promising results and the logical next step is the combination of polidocanol foam with rubber-band ligation (the historical counterpart of sclerotherapy) in a technique called “sclerobanding”. In this article, we comment on the publication by Qu et al further modifying the use of sclerobanding through an endoscopic delivery for patients with grade II-III internal hemorrhoids, and present results compared with endoscopic rubber band ligation. The results achieved are promising.
Beyond the tumor region: Peritumoral radiomics enhances prognostic accuracy in locally advanced rectal cancer
Authors: Liang Zhi-Ying , Yu Mao-Li , Yang Hui , Li Hao-Jiang , Xie Hui , Cui Chun-Yan , Zhang Wei-Jing , Luo Chao , Cai Pei-Qiang , Lin Xiao-Feng , Liu Kun-Feng , Xiong Lang , Liu Li-Zhi , Chen Bi-Yun
Published: January 2025

BACKGROUND

The peritumoral region possesses attributes that promote cancer growth and progression. However, the potential prognostic biomarkers in this region remain relatively underexplored in radiomics.

AIM

To investigate the prognostic value and importance of peritumoral radiomics in locally advanced rectal cancer (LARC).

METHODS

This retrospective study included 409 patients with biopsy-confirmed LARC treated with neoadjuvant chemoradiotherapy and surgically. Patients were divided into training (n = 273) and validation (n = 136) sets. Based on intratumoral and peritumoral radiomic features extracted from pretreatment axial high-resolution small-field-of-view T2-weighted images, multivariate Cox models for progression-free survival (PFS) prediction were developed with or without clinicoradiological features and evaluated with Harrell’s concordance index (C-index), calibration curve, and decision curve analyses. Risk stratification, Kaplan-Meier analysis, and permutation feature importance analysis were performed.

RESULTS

The comprehensive integrated clinical-radiological-omics model (ModelICRO) integrating seven peritumoral, three intratumoral, and four clinicoradiological features achieved the highest C-indices (0.836 and 0.801 in the training and validation sets, respectively). This model showed robust calibration and better clinical net benefits, effectively distinguished high-risk from low-risk patients (PFS: 97.2% vs 67.6% and 95.4% vs 64.8% in the training and validation sets, respectively; both P < 0.001). Three most influential predictors in the comprehensive ModelICRO were, in order, a peritumoral, an intratumoral, and a clinicoradiological feature. Notably, the peritumoral model outperformed the intratumoral model (C-index: 0.754 vs 0.670; P = 0.015); peritumoral features significantly enhanced the performance of models based on clinicoradiological or intratumoral features or their combinations.

CONCLUSION

Peritumoral radiomics holds greater prognostic value than intratumoral radiomics for predicting PFS in LARC. The comprehensive model may serve as a reliable tool for better stratification and management postoperatively.
Creative thinking: Skill development framework. 2nd edition
Authors: Heard Jonathan , Ramalingam Dara , Scoular Claire , Anderson Prue , Duckworth Daniel
Published: January 2025

This creative thinking skill development framework addresses challenges associated with teaching and assessing creative thinking. It provides a definition of creative thinking and describes this construct as it applies in classroom-based learning. The framework synthesises and harmonises existing theory and research on creative thinking and outlines creative thinking processes along prescribed strands and aspects that are informed by evidence. The strands contained within the framework are 1. Generating ideas; 2. Experimenting with ideas; and 3. Identifying the quality
of ideas. The strands are further broken down into aspects to inform teaching and assessment.
THE ART OF CRAFTING EFFECTIVE CONCLUSIONS: A DATA-DRIVEN APPROACH
Authors:   Associate professor (PhD), University of Journalism and Mass Communications of Uzbekistan, Uzbekistan, Shavkatovna Djurakulova Gulnoza
Published: January 2025

This paper examines the pivotal role of conclusions in speeches at international journals, analyzingvarious linguistic strategies, cognitive theories, and empirical evidence to highlight the elements of an effective conclusion. It explores how conclusions not only summarize key points but also serve as powerful tools for reinforcing messages, enhancing audience engagement, and fostering long-term impact. Using a mixed-methods approach, the study draws on both qualitative content analysis of global speeches and quantitative survey data from diverse international audiences. The results emphasize the importance of clarity, emotional resonance, and cultural sensitivity in crafting conclusions that leave a lasting impression.
REFLECTIONS ON THE IMAGE OF THE NIGHTINGALE
Authors:   Doctoral student of the Institute of Uzbek language, literature and folklore of the Academy of Sciences of the Republic of Uzbekistan, Muslima Kholboyeva
Published: January 2025

Uzbek literature attracts the attention of literary critics with its diversity and wide range of images. From ancient times to the present day, these images have been manifested in their own unique way. Most of the images came from society and nature, and were initially found in examples of folk oral art. Classical literature serves as the foundation for the development of most of them. Theimage of the nightingale is widely used in both folk oral art and fiction. In folklore, it is found in songs, proverbs, folk epics and riddle, askia, and in fiction, it is found in Mahmud Kashgari's "Devoni lug'otut-turk". This article analyzes the genesis of this image and the scope of its use in Uzbek classical literature.
FEATURES OF HEART RATE VARIABILITY (HRV) AND INDICATORS OF DAILY BLOOD PRESSURE MONITORING (ABPM) IN PATIENTS WITH DIABETES MELLITUS WITH DIFFERENT PATHOGENETIC SUBTYPES OF ISCHEMIC STROKE
Authors:   Doctor of Medical Sciences, Professor, Bukhara State Medical Institute, Bukhara, Uzbekistan, Urinov Muso Boltayevich
Published: January 2025

Heart rate variability (HRV) and daily blood pressure monitoring (ABPM) serve as critical tools in assessing cardiovascular and autonomic regulation in patients with ischemic stroke (IS). In individuals with concomitant type 2 diabetes mellitus (T2DM), these parameters may differ significantly, influenced by the interplay between the systemic metabolic dysregulation of T2DM and cerebrovascular pathology. This study explores HRV and ABPM characteristics in 256 patients with IS, divided into groups based on the presence of T2DM, to delineate the impacts of diabetes on stroke-related cardiovascular dysregulation.
THE PROCESSES OF TRANSITIONING TO THE UZBEK SCRIPT BASED ON THE LATIN ALPHABET IN UZBEKISTAN
Authors:   Doctor of Philological Sciences, Associate Professor, Tashkent State University of Uzbek Language and Literature Named After Alisher Navoi, Uzbekistan, Azimov Inomjon Mamasodikovich
Published: January 2025

For centuries, the Arabic script served as the primary writing system for many Turkic peoples, including the Uzbeks, Kazakhs, Kyrgyz, Turkmens, Turks, Azerbaijanis, and Tatars. The long history and cultural heritage of these peoples are closely linked to this script.

At the beginning of the last century, the emergence of the Jadid movement in Azerbaijan and Turkey, its spread to other Turkic peoples, the establishment of new Jadid schools, and the development of national press brought to light the challenges of teaching literacy using the Arabic alphabet. Consequently, discussions about reforming and adapting the Arabic script to the needs of national languages became a pressing issue.

Indeed, the Arabic alphabet, which was not inherently designed for Turkic languages, faced numerous challenges. It failed to fully represent the phonetics of Turkic languages, included letters unique to the Arabic language (foreign characters), and was unable to adequately convey the rich vowel system of Turkic languages.

The Jadids, who devoted their lives to promoting literacy, simplifying teaching methods in their newly established schools, and creating accessible textbooks, took steps to reform the Arabic alphabet. They introduced specific forms for vowels. However, the reformed alphabet did not meet expectations, and difficulties in education and publishing persisted.

As a result, efforts to abandon the Arabic script and transition to the Latin alphabet began. During this process, Jadid enlightenment leaders developed four alphabet projects. This article discusses these projects in detail.
Strategic Planning for Sustainable Tourism Development in Pariaman City
Authors: Adrisoni  , Lukman Syukri , Pujani Vera
Published: January 2025

This study aims to determine Strategic Planning for Sustainable Tourism Development in Pariaman City. It is noted that six informants from the government have participated in this study to help develop tourism in Pariaman City. This study was conducted qualitatively through case studies, this study uses data collection through interviews with informants who have been determined based on the needs and suitability of the problem formulation, then Formulation is carried out with the Quantitative Strategy Planning Matrix (QSPM) Strategy, then Strategy Recommendations and action results in the form of Milestones. Based on the assessment of competition between marine tourism in Pariaman City, it is assessed based on the Competitive Profile Matrix (CPM). Marine tourism that is assessed as a competitive profile is Angso Duo Island, Kasiak Island, and Tangah Island. With the results of the three marine tours, Angso Duo Island is indicated as a potential marine tourism for tourism development. Then based on the results of the QSPM Matrix analysis, a score of 5.704 was obtained, which means that from the selected alternative strategies, the most appropriate strategy to be carried out at this time is an intensive strategy (tourism penetration, tourism development, and product development) or integrative (backward integration, forward integration, and horizontal integration). In conclusion, the main focus that needs to be done in tourism development in Pariaman City is to develop tourism quality through increasing events and characteristic tourism products.
Impact of Innovativeness and Total Quality Management (TQM) on Operational Performance Trough Competitions in XXX Company
Authors: Wijaya Rudi , Lukman Syukri , Amali Rivai Harif
Published: January 2025

This research aims to determine the influence of innovativeness and total quality management (TQM) on operational performance through competitive advantage at company XXX. This type of research is quantitative. The sampling method used in this research is probability sampling so the total sample in this research is 164 respondents. The data analysis technique in this research uses descriptive statistical analysis and structural equation modeling (SEM). The results of Innovativeness (X1) have no effect on Competitive Advantage (Z), Innovativeness (X1) has a positive and significant effect on Operational Performance (Y), Total Quality Management (X2) has no effect on Competitive Advantage (Z), Total Quality Management (X2 ) has a positive and significant effect on Operational Performance (Y), Competitive Advantage (Z) has a positive and significant effect on Operational Performance (Y), Innovativeness (X1) has a positive and significant effect on Operational Performance (Y) through Competitive Advantage (Z) and Total Quality Management (X2) has no effect on Operational Performance (Y) through Competitive Advantage (Z) at Company XXX.
The Influence of Good Corporate Governance on the Financial Performance of Food and Beverage Companies Listed on the Indonesia Stock Exchange in 2021-2023
Authors: Fazila Paula , Hijriah Amanah , Rusliyawati
Published: January 2025

This study aims to evaluate the impact of Good Corporate Governance (GCG) on the financial performance of food and beverage companies listed on the Indonesia Stock Exchange (IDX) for the period 2021-2023. The research employs a quantitative method with an explanatory research type. Data were collected from annual reports and financial statements of companies using purposive sampling technique, resulting in a sample of 33 companies. Data analysis was conducted using SPSS software through several stages of testing. The findings indicate that institutional ownership has a significant positive impact on the financial performance of companies, as assessed through Return on Assets (ROA), while the independent board of commissioners has a significant negative impact and the audit committee shows no significant impact. Overall, GCG variables have a significant influence on the financial performance of companies, with institutional ownership playing a crucial role in enhancing management oversight.
Pengaruh Pengungkapan Akuntansi Lingkungan dan Mekanisme Good Corporate Governance Terhadap Nilai Perusahaan
Authors: Yulianti Selvi , Rezky Amalya Wulan
Published: January 2025

The purpose of this study is to assess the impact of environmental accounting disclosure and Good Corporate Governance (GCG) processes on firm value in pharmaceutical businesses listed on the Indonesia Stock Exchange (IDX) between 2021 and 2023. The context of this study is the rising recognition of the significance of sustainability and good governance in the pharmaceutical business following the epidemic. This research employs a quantitative approach, focusing on both descriptive and causal analyses. Data were collected from pharmaceutical firms' annual reports and evaluated using multiple linear regression. The findings reveal that environmental accounting disclosure has a considerable impact on business value, but the GCG method has no meaningful effect. The study concludes that investments in sustainable environmental initiatives significantly enhance business value, though further improvement in GCG practices is necessary to maximize its impact.
The Effect of Return on Risk Assets (RORA), Loan To Deposit Ratio (LDR) and Capital Adequacy Ratio (CAR) on Stock Prices (Empirical Study on Banking Sector Companies on the Indonesia Stock Exchange in 2020-2023)
Authors: Purwati Asih , Mareta Sigit
Published: January 2025

This study aims to determine the effect of Capital Adequacy Ratio (CAR), Loan To Deposit Ratio (LDR), Return On Risk Asset (RORA), on Stock Prices (Empirical Study of Banking Sector Companies on the Indonesia Stock Exchange 2020-2023). The approach used in this study uses a quantitative research approach, namely data that can be measured on a numerical scale. The data source used in this study is secondary data, this study has a population of 47 banking companies and a sample of 42 banking companies This research was tested using panel data analysis which was processed using Eviews Version 13. The results of this study are Return On Risk Asset (RORA) & Loan To Deposit Ratio have no effect on the price of banking shares listed on the IDX in 2020-2023, while the Capital Adequacy Ratio (CAR) affects the price of banking shares on the IDX in 2020-2023. The results of this study are expected to benefit decision makers in the banking sector, including bank executives, regulators, and investors. They can use these results as a basis for making strategic decisions regarding risk management, capital allocation, and investment decisions.
The Effect of Work Environment on Employee Loyalty Mediated by Employee Satisfaction at XYZ Company
Authors: Aldhia Rachmi Riezfa , Siti Hadijah Hady , Setiawan Yana
Published: January 2025

Employees are an asset to the company. The success of a company is highly dependent on the quality of its employees. Changes in the era of globalization demand the existence of employees who have the ability to compete. As one of the private companies, of course, company XYZ must be able to have qualified employees in order to excel from similar competitors. One of the aspects possessed by qualified employees is a high level of loyalty. This study aims to evaluate the level of loyalty of employees of XYZ company that is affected by the work environment and mediated by employee satisfaction. This study uses a verifiable descriptive approach, with a sample of 68 informants. Data collection was carried out through a questionnaire with data processing using SEM-PLS. The findings of the study show that the work environment has a significant effect on employee loyalty levels. On the continuum line, the work environment and employee loyalty are in the high category. This research also highlights the need for XYZ company to improve the professional equipment used to support Employee Loyalty which ultimately affects the company's performance. This research also highlights the need for XYZ company to improve the professional equipment used to support employee loyalty which ultimately affects the company's performance.
Efisiensi dan Efektivitas Pengelolaan Anggaran Pada Tim Kerja Keuangan dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset dan Teknologi
Authors: Hasoloan Dean Leonard , Subagja Iwan Kurniawan , Hakim Azis
Published: January 2025

Perumusan masalah dalam penelitian ini adalah bagaimana pengelolaan anggaran, faktor-faktor yang mempengaruhi serta upaya meningkatkan  pengelolaan anggaran pada Tim Kerja Keuangan Dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset Dan Teknologi. Adapun tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis pengelolaan anggaran, faktor-faktor yang mempengaruhi serta upaya meningkatkan pengelolaan anggaran pada Tim Kerja Keuangan Dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset Dan Teknologi. Metode penelitian ini merupakan penelitian kualitatif dengan desain studi kasus deskriptif. Dalam penelitian ini informan yang diwawancarai berjumlah 5 orang. Teknik analisis data yang digunakan adalah reduksi data, penyajian data dan penarikan kesimpulan serta verifikasi. Hasil dari penelitian ini diperoleh kesimpulan: (1) Pengelolaan anggaran Tim Kerja Keuangan Dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset Dan Teknologi, sudah dikelola dengan baik karena pengelolaan anggaran dilakukan berdasarkan peraturan yang berlaku untuk mencapai efektivitas dan efisiensi dari segi proses administrasi. Namun masih ada beberapa hal yang mungkin dapat dilakukan penyesuaian. (2) Faktor-faktor yang mempengaruhi pengelolaan anggaran pada Tim Kerja Keuangan Dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset Dan Teknologi, antara lain perencanaan anggaran, kualitas sumber daya manusia, koordinasi kerja dalam organisasi, sarana prasarana kegiatan kerja dan supervisi pimpinan. (3) Upaya untuk meningkatkan efektivitas dan efisiensi pengelolaan anggaran pada Tim Kerja Keuangan Dan Barang Milik Negara Sekretariat Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan, Kebudayaan, Riset Dan Teknologi, dapat dilakukan dengan cara meningkatkan kualitas sumber daya manusia, melengkapi sarana prasarana kerja secara maksimal, koordinasi kerja dan sinergitas antar pemangku kepentingan lebih ditingkatkan lagi, serta komitmen yang kuat dari seluruh pegawai dan pimpinan.