bluuebunny/crossref_metadata_2025 huggingface dataset:
Peripheral tissue hypoperfusion predicts post intubation hemodynamic instability
Authors: Dubée Vincent , Hariri Geoffroy , Joffre Jérémie , Hagry Julien , Raia Lisa , Bonny Vincent , Gabarre Paul , Ehrminger Sebastien , Bigé Naike , Baudel Jean-Luc , Guidet Bertrand , Maury Eric , Dumas Guillaume , Ait-Oufella Hafid
Published: July 2022

Background

Tracheal intubation and invasive mechanical ventilation initiation is a procedure at high risk for arterial hypotension in intensive care unit. However, little is known about the relationship between pre-existing peripheral microvascular alteration and post-intubation hemodynamic instability (PIHI).

Methods

Prospective observational monocenter study conducted in an 18-bed medical ICU. Consecutive patients requiring tracheal intubation were eligible for the study. Global hemodynamic parameters (blood pressure, heart rate, cardiac function) and tissue perfusion parameters (arterial lactate, mottling score, capillary refill time [CRT], toe-to-room gradient temperature) were recorded before, 5 min and 2 h after tracheal intubation (TI). Post intubation hemodynamic instability (PIHI) was defined as any hemodynamic event requiring therapeutic intervention.

Results

During 1 year, 120 patients were included, mainly male (59%) with a median age of 68 [57–77]. The median SOFA score and SAPS II were 6 [4–9] and 47 [37–63], respectively. The main indications for tracheal intubation were hypoxemia (51%), hypercapnia (13%), and coma (29%). In addition, 48% of patients had sepsis and 16% septic shock. Fifty-one (42%) patients develop PIHI. Univariate analysis identified several baseline factors associated with PIHI, including norepinephrine prior to TI, sepsis, tachycardia, fever, higher SOFA and high SAPSII score, mottling score ≥ 3, high lactate level and prolonged knee CRT. By contrast, mean arterial pressure, baseline cardiac index, and ejection fraction were not different between PIHI and No-PIHI groups. After adjustment on potential confounders, the mottling score was associated with a higher risk for PIHI (adjusted OR: 1.84 [1.21–2.82] per 1 point increased; p = 0.005). Among both global haemodynamics and tissue perfusion parameters, baseline mottling score was the best predictor of PIHI (AUC: 0.72 (CI 95% [0.62–0.81]).

Conclusions

In non-selected critically ill patients requiring invasive mechanical ventilation, tissue hypoperfusion parameters, especially the mottling score, could be helpful to predict PIHI.
Aspect dependent-based ghost suppression for extended targets in through-the-wall radar imaging under compressive sensing framework
Authors: Rambika Mugundu , Abdalla Abdi T. , Maiseli Baraka , Amour Idrissa , Mwambela Alfred
Published: July 2022

Several approaches have been proposed to suppress multipath ghost in through-the-wall radar imaging (TWRI). One classical approach, called Aspect Dependent (AD), exploits locations of ghosts in the images without demanding prior knowledge of the reflecting geometry. This operation strategy makes the method superior over multipath exploitation-based approaches. However, the AD method assumes a point target that emulates unreal environment. Therefore, reconstructing extended targets with this method leads to incorrect scene interpretation. This work proposes a ghost suppression method for extended targets based on the AD feature that exploits duo sub-apertures. Firstly, we evaluate the best suppression method using a performance metric called relative clutter peak. Next, the evaluated method is extended to encompass a target extent during sub-images reconstruction. Following this strategy, an effective image fusion method suitable for extended targets is proposed. The method considers pixel neighborhood to effectively recover the given extended target. Simulation results show that, when signal-to-noise ratio is 20dB, the proposed method significantly improves signal-to-clutter ratio and relative clutter peak by 8.8% and 23.8%, respectively, relative to the existing AD based methods under point target assumption.
Palpation localization of radial artery based on 3-dimensional convolutional neural networks
Authors: Chen Qiliang , Huang Yulin , Zhu Xing , Lu Hong , Ji Zhongzhi , Yang Jiacheng , Luo Jingjing
Published: July 2022

Palpation localization is essential for detecting physiological parameters of the radial artery for pulse diagnosis of Traditional Chinese Medicine (TCM). Detecting signal or applying pressure at the wrong location can seriously affect the measurement of pulse waves and result in misdiagnosis. In this paper, we propose an effective and high accuracy regression model using 3-dimensional convolution neural networks (CNN) processing near-infrared picture sequences to locate radial artery upon radius at the wrist. Comparing with early studies using 2-dimensional models, 3Dcnn introduces temporal features with the third dimension to leverage pulsation rhythms, and had achieved superior performance accuracy as 0.87 within 50 pixels at testing resolution of 1024 × 544. Model visualization shows that the additional dimension of the temporal convolution highlights dynamic changes within image sequences. This study presents the great potential of our constructed model to be applied in real wrist palpation location scenarios to bring the key convenience for pulse diagnosis.
Weakly supervised spatial–temporal attention network driven by tracking and consistency loss for action detection
Authors: Zhu Jinlei , Chen Houjin , Pan Pan , Sun Jia
Published: July 2022

This study proposes a novel network model for video action tube detection. This model is based on a location-interactive weakly supervised spatial–temporal attention mechanism driven by multiple loss functions. It is especially costly and time consuming to annotate every target location in video frames. Thus, we first propose a cross-domain weakly supervised learning method with a spatial–temporal attention mechanism for action tube detection. In source domain, we trained a newly designed multi-loss spatial–temporal attention–convolution network on the source data set, which has both object location and classification annotations. In target domain, we introduced internal tracking loss and neighbor-consistency loss; we trained the network with the pre-trained model on the target data set, which only has inaccurate action temporal positions. Although this is a location-unsupervised method, its performance outperforms typical weakly supervised methods, and even shows comparable results with some recent fully supervised methods. We also visualize the activation maps, which reveal the intrinsic reason behind the higher performance of the proposed method.
Uniqueness and Ulam–Hyers–Rassias stability results for sequential fractional pantograph q-differential equations
Authors: Houas Mohamed , Martínez Francisco , Samei Mohammad Esmael , Kaabar Mohammed K. A.
Published: July 2022

We study sequential fractional pantograph q-differential equations. We establish the uniqueness of solutions via Banach’s contraction mapping principle. Further, we define and study the Ulam–Hyers stability and Ulam–Hyers–Rassias stability of solutions. We also discuss an illustrative example.
Quassia amara bioactive compounds as a Novel DPP-IV inhibitor: an in-silico study
Authors: Olugbogi Ezekiel A. , Bodun Damilola S. , Omoseeye Shola D. , Onoriode Anita O. , Oluwamoroti Favour O. , Adedara Joshua F. , Oriyomi Isaac A. , Bello Fatimat O. , Olowoyeye Favour O. , Laoye Oluwatomilola G. , Adebowale Damilola B. , Adebisi Aanuoluwapo D. , Omotuyi Olaposi I.
Published: July 2022

Background

Diabetes, a cardiometabolic condition with social and health ramifications, is already a global epidemic. Diabetes affects 422 million people worldwide, with the majority living in middle- and low-income countries, resulting in 1.5 million deaths each year. Inhibiting DPP-IV, an enzyme whose main biological function in diabetes is the breakdown of metabolic hormones like GLP-1, Quassia amara, a plant that contains numerous phytochemicals, has been claimed to be used as a traditional treatment for a variety of metabolic illnesses, as well as having anti-malaria, anti-biotic, anti-diabetes, and anti-anemic characteristics. This work investigated the in-silico inhibitory ability of phytochemicals obtained from Quassia amara against a diabetes-related enzyme, DPP-IV, with the aim of confirming the drug-like potential of ligands from the plant (Quassia amara) in comparison with the standard drug, Alogliptin.

Result

As a result of the investigation, five compounds (Vitexin, Quassimarin, Simalikalactone D, Brucein D, and Quassinol) obtained docking scores ranging from − 7.47 to − 6.49 kcal/mol.

Conclusion

Many medications have been offered, but the typical side effects have prompted researchers to look for new herbal plants which can be used as permanent treatment with minute side effects. Thus, utilizing computational studies such as molecular docking, molecular mechanics generalized born surface area (MM-GBSA) and the lead compounds' ADMETox characteristics were computed.
A rare case of pituicytoma-related hypercortisolism in a patient with Cushing syndrome—case report
Authors: Amoateng Magdelene , Ibrahim Eiman , Ahmad Yasir , Calikyan Anoush , Hulinsky Ilja
Published: July 2022

Background

Distinguishing between a pituitary adenoma and a pituicytoma can be challenging. Hormonal changes in pituicytomas are uncommon, and the tumor's mass effect has triggered most symptoms. There were only two reported cases of pituicytoma with elevated hormonal levels in patients who presented with Cushing syndrome as of 2017.

Case presentation

This report describes a rare case of a patient who had Cushing syndrome from a pituitary-related hypercortisolism, most likely a pituicytoma with neuroendocrine features with the benefit of early detection and surgical resection.

Conclusions

Pituicytomas have malignant tendencies while pituitary adenomas are mostly benign, hence the need to distinguish them accurately for prompt treatment and improved prognosis.
The influence of age and weight on the outcomes of complete atrioventricular septal defect repair
Authors: Al-Wassia Heidi K. , Al-Radi Osman O. , Maghrabi Khadijah A. , Bayazeed Mawadda A. , Qattan Murooj M. , Ebraheem Doaa T. , Gadi Sarah U. , Kattan Mernan F. , Alghamdi Reema A. , Alzabidi Samaher H. , Dohain Ahmed M.
Published: July 2022

Background

The appropriate age and weight for surgical repair of atrioventricular septal defect (AVSD) is an area of controversy. We aimed to study the effect of weight and age at the time of surgical repair for complete AVSD in children less than 2 years of age on postoperative outcomes. A retrospective data review was performed for patients who underwent the AVSD repair from 2012 to 2019 at our institutions. Our primary outcome was the postoperative in-hospital length of stay (LOS). Secondary outcomes included total positive pressure ventilation (PPV), ventilation time, maximum vasoactive–inotropic score (max VIS), and other postoperative complications.

Results

The study included fifty patients. The median age was 191 days, and the median weight was 4.38 kg at the time of surgery. Weight < 4 kg was associated with longer PPV time and postoperative in-hospital LOS (p value of 0.033 and 0.015, respectively). Additionally, they had higher max VIS at 24 h and 48 h than the other groups with bodyweight 4–5.9 kg or ≥ 6 kg (p value of 0.05 and 0.027, respectively). Patients with older age or lower weight at operation had a longer in-hospital LOS and total length of PPV after surgery. There were no postoperative in-hospital deaths.

Conclusions

Older age and lower weight at the time of surgical repair of atrioventricular septal defect could be independent predictors of prolonged postoperative in-hospital length of stay and total length of positive pressure ventilation.
Lung shunt fraction quantification methods in radioembolization: What you need to know
Authors: Torkian Pooya , Ragulojan Ranjan , J. Woodhead Gregory , D'Souza Donna , Flanagan Siobhan , Golzarian Jafar , Young Shamar
Published: July 2022

In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the most commonly utilized and easiest to perform, however new dosimetry software provides the ability to use more advanced 3D techniques. This paper reviews the different LSF calculation methods and elucidates the available data comparing the techniques, clinical relevance, and dose calculation.
Type III-A CRISPR systems as a versatile gene knockdown technology
Authors: Woodside Walter T. , Vantsev Nikita , Catchpole Ryan J. , Garrett Sandra C. , Olson Sara , Graveley Brenton R. , Terns Michael P.
Published: July 2022

CRISPR-Cas systems are functionally diverse prokaryotic antiviral defense systems, which encompass six distinct types (I–VI) that each encode different effector Cas nucleases with distinct nucleic acid cleavage specificities. By harnessing the unique attributes of the various CRISPR-Cas systems, a range of innovative CRISPR-based DNA and RNA targeting tools and technologies have been developed. Here, we exploit the ability of type III-A CRISPR-Cas systems to carry out RNA-guided and sequence-specific target RNA cleavage for establishment of research tools for post-transcriptional control of gene expression. Type III-A systems from three bacterial species (L. lactis, S. epidermidis, and S. thermophilus) were each expressed on a single plasmid in E. coli, and the efficiency and specificity of gene knockdown was assessed by northern blot and transcriptomic analysis. We show that engineered type III-A modules can be programmed using tailored CRISPR RNAs to efficiently knock down gene expression of both coding and noncoding RNAs in vivo. Moreover, simultaneous degradation of multiple cellular mRNA transcripts can be directed by utilizing a CRISPR array expressing corresponding gene-targeting crRNAs. Our results demonstrate the utility of distinct type III-A modules to serve as specific and effective gene knockdown platforms in heterologous cells. This transcriptome engineering technology has the potential to be further refined and exploited for key applications including gene discovery and gene pathway analyses in additional prokaryotic and perhaps eukaryotic cells and organisms.
Effect of perceived risk, challenges, and coping on anxiety and depression among frontline health workers during the COVID-19 pandemic in Bangladesh
Authors: Karim Md Rizwanul , Ahmed Helal Uddin , Shaoli Salowa Salam
Published: July 2022

Background: During the COVID-19 pandemic the health care workers (HCWs) encountered one of the heaviest blows by saving lives while endangering their own. This study was carried out to investigate risk exposures, risk perceptions, challenges, and coping strategies, leading to anxiety and depression, among HCWs in Bangladesh.

Methods:  This hospital-based cross-sectional survey was conducted from February to July 2021 among 1,112 frontline HCWs. Data were collected using a pre-tested self-administered questionnaire including Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) scale. A coping scale for COVID-19 (CS-COV-19) was developed and validated. To determine the predictors for symptoms of depression and anxiety, multivariable logistic regression analysis was performed, and the associations between key variables are presented as odds ratios (ORs) and 95% CIs.

Results: A total of 54.9% (n=389) doctors and 51.4% (n= 207) nurses were found to have mild to severe anxiety status and 47% (n=333) doctors and 39.9% (n= 159) nurses were found to have mild to severe depression. HCWs, family members, neighbors had been affected with COVID-19 and those who experienced extra stresses at work were two times more likely to have anxiety. HCWs who had worried family and friends that they might get infected through them, confronted any negative social attitude or perceptions, decreased monthly income, and depression were 1.57 to 1.8 times more likely to experience anxiety than those who did not go through these experiences. Health workers who confronted negative social attitudes or social perceptions were 1.7 times more likely to have depression. Respondents, who had family members infected with COVID-19 and HCWs who worked for long hours at hospitals were almost two times more likely to have depression.

Conclusions: The findings will help promoting advocacy and encourage implementing selective interventions to protect the mental health and wellbeing of HCWs working with COVID-19.
Use of lasers in hidradenitis suppurativa treatment – case report
Authors: Kozinska Urszula , Gras-Ozimek Jordi , Kozińska Iga
Published: July 2022

Acne inverse sometimes known as hidradenitis suppurativa is a long-term dermatological condition. Due to the poorly examined nature of the disease the effectiveness of its treatments is unclear. More than 50 interventions have been described and therefore its diagnostic and the treatment can be challenging. The aim of this case report is to draw attention to the possible use of laser therapy in the treatment of hidradenitis suppurativa.

A case report.

We report the case of 27-year-old woman that has been successfully treated with laser after years of an ineffective treatment. Due to the failure of systemic and local antibiotic therapy, hormone therapy, surgical drainage and orally and externally applied retinoids, removal of lesions using a CO2 laser knife and a fractional laser therapy combining a CO2 laser and a 1570 nm wavelength laser on the surface of the affected skin was performed.

Conclusions.

The use of laser therapy, with particular emphasis on the CO2 laser, may be an important and effective element of hidradenitis suppurativa treatment.
Konferencja Komisji Historii Starożytnej PTH „Świat starożytny – centrum i peryferie”, Wrocław, 14-16 września 2021 r
Authors: Pawlak Marcin
Published: July 2022

Sprawozdanie z konferencji Komisji Historii Starożytnej PTH „Świat starożytny – centrum i peryferie”, która odbyła się w dniach 14-16 września 2021 roku we Wrocławiu.
Prácticas sociales, servicio ambiental y cambio climático: axiología de lo humano y no-humano en los Cerros Orientales de Bogotá
Authors: Fracasso Liliana , Betancourt Carolina , Aperador David
Published: July 2022

Los Cerros Orientales representan un importante referente simbólico y una de las principales estructuras ecológicas de Bogotá D. C. Su historia ambiental en el siglo xx, se ha caracteriza­do por un progresivo desbordamiento de la demanda social en relación con la oferta natural, frente a la cual la política pública ha procurado dar respuesta con acciones de ordenamiento ambiental del territorio. Con el objetivo de repensar críticamente la idea de servicio ambiental y de patrimonio cultural, a partir de datos empíricos y una retrospectiva de las configuraciones territoriales de este borde urbano, se reconocen dinámicas internas, externas y de contraten­dencias a la necesidad de implementar medidas para el cambio climático. Se concluye que las formas de concebir y valorar los Cerros Orientales necesitan de una axiología expandida, que renueve las prácticas sociales superando la ambivalencia hombre-naturaleza que caracteriza los actuales procesos de patrimonialización.
Forecast Selection and Representativeness
Authors: Petropoulos Fotios , Siemsen Enno
Published: July 2022

Effective approaches to forecast model selection are crucial to improve forecast accuracy and to facilitate the use of forecasts for decision-making processes. Information criteria or cross-validation are common approaches of forecast model selection. Both methods compare forecasts with the respective actual realizations. However, no existing selection method assesses out-of-sample forecasts before the actual values become available—a technique used in human judgment in this context. Research in judgmental model selection emphasizes that human judgment can be superior to statistical selection procedures in evaluating the quality of forecasting models. We, therefore, propose a new way of statistical model selection based on these insights from human judgment. Our approach relies on an asynchronous comparison of forecasts and actual values, allowing for an ex ante evaluation of forecasts via representativeness. We test this criterion on numerous time series. Results from our analyses provide evidence that forecast performance can be improved when models are selected based on their representativeness.

This paper was accepted by Manel Baucells, behavioral economics and decision analysis.

Supplemental Material: The online appendix and data are available at https://doi.org/10.1287/mnsc.2022.4485 .
Pengembangan media B-Math berbasis STEM (Science, Technology, Engineering, and Mathematics) pada peserta didik tunanetra
Authors: Indriani Aristia , Erviana Vera Yuli
Published: July 2022

Pendidikan STEM merupakan pendidikan dengan mengintegrasikan berbagai mata pelajaran antara lain sains, teknologi, enggenering, dan matematika. Pengintegrasian beberapa mata pelajaran ini dapat mengembangkan potensi peserta didik dalam belajar terutama dengan hal yang berkaitan dengan pemecahan masalah dalam kehidupan sehari-hari. Namun pada kenyataannya, penyediaan media pembelajaran guna mendukung peningkatan kualitas khususnya bagi tunanetra masih sangat sedikit. Sehingga penelitian ini bertujuan untuk mengembangkan dan mengetahui kualitas media B-Math berbasis STEM bagi peserta didik tunanetra. Penelitian ini menggunakan pendekatan R&D (Research and Development) dengan model four-D (Define, Design, Development, Dissemination). Adapun subjek dalam penelitian ini adalah ahli media, ahli materi, dan ahli bahasa.. Hasil pengembangan pada penelitian ini adalah media braille mathematics (B-Math). Adapun media B-Math ini telah melalui uji validasi oleh para validator yaitu ahli media, ahli materi, dan ahli bahasa. Berdasarkan hasil validasi oleh para validator maka diperoleh nilai 84 dari ahli media dan termasuk dalam kriteria “Sangat Baik”. Penilaian dari ahli materi memperoleh nilai 76 dan termasuk dalam kategori “Baik”. Adapun penilaian dari ahli bahasa memperoleh nilai 85 dan termasuk dalam kategori “Sangat Baik”. Nilai rata-rata yang diperoleh dari penilaian ketiga ahli tersebut adalah 81,67 dan termasuk dalam kriteria “Sangat Baik”.
Practice-oriented Technologies in the Training of Competitive Specialists in the Information and Documentation Industry
Authors:   State Institution Luhansk Taras Shevchenko National University, Liesovets Nelya
Published: July 2022

In the article examines the problem of training competitive specialists in information, library and archival affairs in higher education institutions. Substantiation of the concepts «technology», «practice-oriented technologies», «professional culture of a specialist in the information and documentation industry» are presented. Through clarifying the essence of the concept of «learning technology», defining its structure, the expediency of using practice-oriented technologies as the most appropriate tool of the educational process, which results in the skilful application of acquired knowledge and skills in practice. It is noted that the use of practice-oriented technologies in the training of competitive specialists in the information and documentation industry contributes to a clearer and more regulated influence (both on the part of the teacher and the student) on all stages of the learning process: from providing students with knowledge, skills and abilities – to control of their absorption. In this case, an important condition is to provide feedback (quality, selection of material, consideration of the situation, control, self-control, etc.).
Use of Resources of the Educational Environment in the Context of Remote Studying of Foreigners in Ukraine
Authors:   Poltava State Agrarian University, Tokuyeva Nataliia
Published: July 2022

This article examines the essence of the educational environment concept, іndividual approaches of scientists to determining the content and structural components, means and forms of its main tasks within the format of remote studying of foreign citizens in Ukrainian higher educational facilities, which is determined and adjusted by time, society, forms of the educational process. The peculiarities of the organization of the virtual educational environment through the lens of language training of foreigners in Ukrainian higher educational facilities, content, purpose and level of efficiency of its resources for solving educational tasks of an educational facility, are revealed. External resources of the educational environment are examined, and internal interrelated components that ensure its effectiveness and efficiency are highlighted: technological (using normative methods of teaching Ukrainian as a foreign language and achieving planned results), material-technical, and subject-resource (implementing equal partnership between the subjects of the educational environment). It is determined that at the initial stage of education, the lack of language and cultural environment, which contributes to foreigners’ formation of speech skills and abilities, determines their communication needs and motivates them to learn the language, negatively affects the quality of education. Daily verbal communication with the tutor in the format of videoconferencing, involvement of authentic videos, fragments of television programs, films or cartoons, educational videos, virtual tours, phonograms in the educational process provides an opportunity to optimize the educational process and achieve planned studying outcomes.
To the Question of International Experience in the Professional Training of Future Specialists in the Socionomic Sphere to Work With Families Raising Children With Special Needs
Authors:   IHE ", Fayerman Olena ,   Alfred Nobel University"
Published: July 2022

The article is devoted to the analysis of scientists’ views on international experience in the professional training of future specialists in the socionomic sphere to work with families raising children with special needs (master's level). Peculiarities of theoretical and practical training of future specialists in the social sphere (master's level) in colleges and universities of the USA, Canada, Sweden, Great Britain, France, Germany, Poland are discussed. According to the world standards, the selected countries demonstrate breakthrough achievements, a high level of professional training of the target group of specialists. The main approaches to the organization of professional training of future specialists in the socionomic sphere are specified, namely the integration of theory and practice in the learning process, interdisciplinary of programs and disciplines, interactivity of educational process organization, participation of stakeholders, practical orientation of the training (activity of students in social agencies under the guidance of mentors). The emphasis is put on certain teaching methods, specifically on discussion, situational, problematic methods, the use of «reflexive breaks», «open communication», practical activities in the laboratory, group forms of work.
Animation Activities in Preschool Education: Essence and Content
Authors:   State Institution Luhansk Taras Shevchenko National University, Grechishkina Iryna , Kovalenko Tamara ,   State Institution Luhansk Taras Shevchenko National University
Published: July 2022

The urgency of the problem of organizing animation activities in preschool institutions is due to the need to organize effective leisure for preschool children on the one hand, on the other – to prepare educators for the successful conduct of this activity. That is why it is worth considering the essence and content of animation activities in modern kindergartens. Animation in preschool institution is interpreted by the authors as an event or set of activities aimed at recreation, entertainment, relief of psychological stress, recovery within the leisure sphere of man. In turn, animation activity is defined as the activity of designing, developing, organizing and conducting special leisure programs with preschool children. The leading types of animation activity in preschool institution include: sports and health or sports and entertainment, entertainment and entertainment, dance and entertainment, cultural and cognitive or excursion, creative and labor; tourist (tourist and health). A number of animation functions in preschool institution are characterized, the leading ones of which are defined as: entertaining, hedonistic, recreational (health-improving), adaptive, educational, developmental, educational, corrective. The influence of different types of animation on the development of the leading spheres of the preschooler's personality is determined.
Health care in the Educational Environment of General Secondary Education Institutions
Authors:   Bogdan Khmelnitsky Melitopol State Pedagogical University, Kovaleva Olga , Tsapko Alla ,   H. S. Skovoroda Kharkiv National Pedagogical University, Prokofieva Olesia ,   Bogdan Khmelnitsky Melitopol State Pedagogical University, Hryshchenko Svitlana ,   Taras Shevchenko National University "Chernihiv Collegium"
Published: July 2022

Priority areas for education reform in Ukraine are defined by the National Strategy for the Development of Education in Ukraine (2013–2021) and the National Strategy for Physical Fitness in Ukraine until 2025. These are: physical education, physical culture, the formation of motor skills and abilities of students. The purpose of the article is to analyze the problem of health care in the educational environment of general secondary education institutions through physical education. The article proves that the health and formation of motor function of students in general secondary education is a complex problem. The problem requires the development of methodological principles, the development of motor function and feedback on the effectiveness of pedagogical influence on the development of motor skills and abilities of students. There is a need to take into account the age, gender and individual characteristics of school students, based on the program which can achieve the most effective results. Object of research: educational process in general secondary education institutions of Ukraine. Subject of research: formation of the process of health care of students of general secondary education institutions of Ukraine. Conclusions. 1. In the conditions of general secondary education institutions there are the following ways to increase the motor activity of students: ensuring the functioning of the motor mode of children; monitoring the state of motor readiness of children; creating conditions for the formation of children's skills of self-organization and self-control, which will promote the activation of motor activity; control of the process of formation of effective motor behavior of students of general secondary education. 2. In order to achieve a high level of physical activity, students need to pay more attention to the process of physical improvement in educational institutions, in the process of upbringing in families and in out-of-school educational institutions. 3. The norm of motor activity in childhood is taken to be the amount of motor activity that fully meets the biological needs of movement, promotes good health. 4. Methods of motor activity of students of general secondary education are as follows: exercises with elements of gymnastics, jumping, games for active recreation, mastering the skills of strength exercises, rhythm in the structure of movement, the ability to control movements.
Esthetic Education of Junior Schoolchildren by Choreography Means
Authors:   SHEE ", Коtоv Volodymyr ,   Donbas State Pedagogical University", Pliukhina Nataliia ,   SHEE "Donbas State Pedagogical University"
Published: July 2022

The article highlights the role of esthetic education for personality formations of junior schoolchildren.. One of the leading means of aesthetic education is the art of dance. For centuries, one of the universal means of aesthetic education has been and remains the art of dance, which represents a holistic picture of the world in the system of views, thoughts, feelings, emotions and their images. In the course of civilizational transformations, the aesthetic and educational status of folk choreography changed, which was determined by its role and place in the system of statehood, education and culture. From ancient times until the end of the XIX century in the cultural life of society choreographic activity was considered from different aspects. The article focuses on the formation of the teacher’s esthetic culture. Qualitative assessments, the ability to feel the world values, the ability to recognize the external manifestations of students’ emotional life turn the sensory act of reflection into an esthetic act of object’s or phenomenon’s understanding in the reality context. The article points out that the teacher’s esthetic assessment is the comparison of object’s or phenomenon’s esthetic qualities with their esthetic ideals in order to further using these concepts, ideas and statements for various types of esthetic activities. The process of formation of teachers’ esthetic statements, tastes, ideals can be formed by intellectual self-education. The field of aesthetic culture of the teacher includes knowledge of aesthetics, nature, work, life and human relations, the basics of methods of aesthetic education and upbringing. The content of the basics of art training of teachers is knowledge of musicology, literature, choreography, as well as folklore and language culture. It should be noted that the basis of practical and constructive field of aesthetic activity of the teacher is the embodiment in the educational process acquired during the spiritual and contemplative activities of aesthetic experiences, emotions and feelings, on the one hand, and aesthetic concepts, judgments, ideas, ideals – on the other. Constructive aesthetic activity of a teacher is the creation of an aesthetic environment for the education of students, ie the use of existing and creation of new aesthetic, educating opportunities for natural, artistic, educational and industrial work of children and youth, their communication and life, as well as artistic and aesthetic activities of teachers. and extracurricular activities with students. Teachers’ and family’s aspects and roles are considered in the sphere of choreographic art.
Provision of Social Services to Vulnerable Categories of the Population as a Type of Professional Activity of a Social Worker
Authors:   State Institution Luhansk Taras Shevchenko National University, Yurkiv Yaroslava
Published: July 2022

Social services are interpreted in a broad and narrow sense: in a broad sense – as creating conditions for citizens for a full life in society, equal opportunities, non-discrimination; in the narrow – as meeting the needs of the individual user by providing personal social services that provide protection against general and specific risks and help to overcome complex personal crises and challenges. Social services are key tools for protecting fundamental human rights and dignity.The article reveals the provision of social services as a type of professional activity of a social worker aimed at social work with various categories of the population, including the vulnerable.Researchers and practitioners determine the list of social support services for vulnerable groups and individuals / families who have been included in the SJO: social services to support children and families with children / youth; social services of alternative care for children, orphans and children deprived of parental care; social services for the support and care of the elderly; integration and rehabilitation services for people with disabilities; services for people in need of adaptation, integration (reintegration); services for people in need of emergency and crisis intervention.The purpose of social work to provide social services to vulnerable groups is social prevention (prevention of SJO), social support (overcoming SJO), social services (minimization of SJO).Accordingly, the purpose of social work with vulnerable groups is to prevent, minimize or overcome difficult life circumstances for their successful socialization and integration into society.
Peculiarities of the Formation of Perception of Temporal Representations in Children with Intellectual Development Disorders
Authors:   MI ", Tarasova Vitaliia ,   Kharkiv Humanitarian and Pedagogical Academy"
Published: July 2022

The article covers the process of forming perception of time for children with intellectual developmental disorders of primary school age. It is noted that the formation of the perception of time and time orientation is one of the most complex areas of knowledge, skills and abilities included in the content of social experience, as they are quite abstract and their operation requires the performance of complex thought operations. Attention is drawn to the fact that the formation of a sense of time in children with intellectual developmental disabilities is not sufficiently investigated and requires further methodology development. The article covers the main theoretical concepts of the formation and development of time perception of children with normative development and children with mental disabilities. And it is also noted that children with strong intellectual development disorders, understanding of the names of the months, skills and abilities to determine the sequence of terms, the concept of a day, time, are formed slowly and with great difficulty. To make it easier to acquire the material, it is recommended to combine the use of different forms of visualization with practical activities and repetition. Consolidation takes place in the form of didactic games, in various educational classes and in everyday life. This option of learning allows for a personal approach to children in the process of forming a sense of time, and it makes it possible to influence their overall development.
Psychological and Pedagogical Conditions for the Organization of Inclusive Educational Space in Higher Education Institutions
Authors:   State Institution Luhansk Taras Shevchenko National University, Tovstukha Olesia
Published: July 2022

The modern sphere of education is aimed at the development of inclusion, a special role in this direction is played by higher education at the organizational, substantive, procedural levels. One of the most important problems is the low level of scientific and methodological and psychological and pedagogical training of teachers to work with students with special needs, this scientific work is devoted to finding ways out of this situation. Among the problems of organizing an effective inclusive space in universities are: psychological unpreparedness of participants in the inclusive process; lack of broad medical, social and psychological and pedagogical support for applicants with disabilities; insufficient level of preparation for study at the university of entrants with psychophysical features; the existence of socio-psychological barriers. Ways to solve these problems are: creation of resource centers; training of teachers on the application of psychological and pedagogical technologies to work with different students; supplementing existing and developing new intra-university documents to ensure access of higher education students with special educational needs to the necessary didactic materials and creating an accessible environment for such students; renewal, retraining and advanced training of tutors, consultants, assistants; development of a set of measures for social and psychological protection (various types of scholarships, financial aid, free vouchers to sanatoriums; advocacy and monitoring of the training of this category of higher education by deans, directorates); introduction of e-learning based on distance learning technologies, etc.
Development of the Future Law Enforcement Officer Digital Competence as a Modern Pedagogical Phenomenon
Authors:   State Institution Luhansk Taras Shevchenko National University, Kochenko Ihor
Published: July 2022

The paper reveals the problems of meaningful development of future law enforcement officer digital competence. A number of similar and sometimes identical concepts are analysed, their relationship with each other is determined, and significant differences are identified. These concepts include information (digital) culture, information (digital) literacy, and a number of others. Based on a comparative analysis, the content components of future law enforcement officer digital competence are identified, and the author's interpretation of the concept of digital competence is proposed and justified. The paper notes that digital competence is a logical continuation of the «evolutionary» chain of concepts associated with informatization processes. The author's concept of future law enforcement officer digital competence has been formulated in the paper. It is an integrative characteristic of the law enforcement officer's personality as a professional which dynamically combines the knowledge, abilities, skills and relationships to use the capabilities of digital resources and digital tools as well as reflects the willingness, competence and responsibility to apply digital technologies to solve professional problems.
Impact Of High Dose Metformin Versus Teneligliptin as add together on to Metformin on Glycemic Control of T2DM Patients
Authors: Poornima. R Poornima. R , Brigida. S Brigida. S , Elizabeth Arul Amutha , Soujania G Soujania G , Lella Tanuja
Published: July 2022

Introduction: Hyperglycaemia and abnormalities in simple carbohydrate, fat and protein metabolism are the characteristic feature of the metabolic disorder, Diabetes Mellitus. Diabetes mellitus treatment is achieved by modifications in diet, sleep pattern, regular physical activity followed by addition of anti-hyperglycemic drugs like metformin if HbA1C levels stays more than 7.0%.Materials and Methods The study period was from April 2019 – September 2019. The total duration of study was 24 weeks. Total 160 patients were screened; among them 100 participants were selected as per the inclusion criteria. Out of 100 patients, only 91 patients have completed the study. Conclusion To conclude DPP-4 inhibitor Teneligliptin 20mg OD exemplifies to be a pertinent add-on to Metformin 500mg BD to enhance the glycaemic control and could be an operative and reliable medication preference in T2DM through decent patient acceptability.
Brain Tumor Segmentation and Classification in MRI using Clustering and Kernel-Based SVM
Authors: Mandle Anil Kumar , Sahu Satya Prakash , Gupta Govind
Published: July 2022

Brain tumor and other nervous systems cancer are one of the leading causes of death for many patients. Magnetic resonance imaging (MRI) is the most important medical imaging modality for diagnosing brain tumors and other disorders in the brain. Manual evaluation of several MRI images by radiologists or experts for diagnosing brain tumors especially at early stages is a challenging task. Hence, this paper proposes an automated framework for the segmentation and classification of brain tumors using K-means clustering and kernel-based support vector machine (K-SVM). The major steps of the proposed framework consist of preprocessing, segmentation, feature extraction with selection, and classification. In the preprocessing step, the regions of interest (ROI) are extracted using skull stripping and a median filter. In the next step, the tumor is segmented using an optimized K-means algorithm. Further, discrete wavelet transform (DWT)-based texture features are used for feature extraction, and significant features are selected by principal component analysis (PCA). Finally, the kernel-based support vector machine (K-SVM) is used for the classification of brain tumor types into benign and malignant, with a dataset using 160 MRI images, consisting of 20 normal and 140 abnormal. Experimental findings demonstrated the efficacy of the proposed framework with 98.75% accuracy, 95.43% precision, and 97.65% recall. The simulation findings emphasize the importance of the proposed system as compared to state-of-the-art techniques in terms of coherence parameters and performance.
Comparison of Propofol-Fentanyl Versus Propofol-Ketamine Combination as Total Intravenous Anesthesia in Maxillofacial Surgical Procedures – A Prospective Randomized Controlled Study
Authors: Tusharbhai Dani Mihir , Baliga Mohan , Kamath Shaila , Mishra Aananya
Published: July 2022

Background: Total intravenous anesthesia (TIVA) is a technique where drugs are administered intravenously for the induction and maintenance of anesthesia instead of volatile drugs, avoiding some of the drawbacks of inhalation anesthesia providing rapid and complete recovery making it suitable for daycare surgeries. Aim: To compare the intraoperative and postoperative hemodynamic patterns, postoperative recovery time, and unwanted consequences such as post-operative nausea and vomiting (PONV) in various maxillofacial procedures using a combination of two drug regimens, namely propofol-ketamine and propofol-fentanyl. Patient & methods: 40 patients between the age group of 18-40 years of either gender were randomly divided into two groups with propofol-ketamine (group 1, n=20) and propofol-fentanyl (group 2, n=20) who underwent various surgical procedures like cyst enucleation, open reduction and internal fixation (ORIF) of facial fractures, orthognathic procedures such as maxillary or mandibular segmental osteotomy and genioplasty with the procedure lasting 60 to 75 minutes. This study compared the total amount of propofol, time of the infusion, and hemodynamic parameters like mean pulse rate (PR), oxygen saturation level (SpO2), systolic blood pressure (SBP) & diastolic blood pressure (DBP), emergence time & recovery time, undesirable sequels like postoperative nausea and vomiting (PONV) and any other side effects between both the groups. Results were analyzed statistically using an independent t-test and chi-square test. Results: A comparison of two groups revealed a significant rise in systolic blood pressure in group 1 as compared to group 2 and group 2 showed better emergence time & recovery time with fewer incidences of postoperative nausea and vomiting and other side effects. Conclusion: Since the propofol-fentanyl provided significantly good results it can be considered as an alternative to gaseous anesthetic agents in various maxillofacial surgical procedures mentioned in the materials with the surgical procedure lasting 60-75 minutes.