bluuebunny/crossref_metadata_2025 huggingface dataset:
TRILHAS DA IMAGINAÇÃO: COMPREENDENDO A CONSTRUÇÃO HISTÓRICA E SOCIAL DO “EXOTISMO AMAZÔNICO” POR UMA LEITURA ECOSSISTÊMICA COMUNICACIONAL
Authors: Lopes Rafael De Figueiredo , Nogueira Wilson De Souza
Published: September 2017

O artigo propõe uma reflexão sobre o contexto exótico e espetacular atribuído à Amazônia, numa perspectiva metodológica ecossistêmica comunicacional, ou seja, analisando o fenômeno na articulação entre fatores históricos, humanos, socioculturais, ambientais e tecnológicos. Desse modo, expõe um mosaico de multiplicidades, procurando resgatar aspectos que contribuíram para a cristalização do imaginário sobre a região, enfocando características relativas à formação do ambiente natural, à presença humana e suas diferentes etnias e às transformações socioculturais ocorridas ao longo do processo histórico.  Percebe-se, que a força de ideologias hegemônicas construíram ideias e valores que ainda se propagam no senso comum, principalmente, pelos meios de comunicação. Assim, as concepções sobre a Amazônia costumam reproduzir símbolos e valores do imaginário colonizado, reforçando estereótipos, clichês culturais e limitando a compreensão das singularidades de uma região heterogênea.
ANÁLISE DO COMPORTAMENTO E UTILIZAÇÃO DAS REDES SOCIAIS PELOS IDOSOS
Authors: Dellarmelin Mateus Luan , Balbinot Valmiria Antonia , Froemming Lurdes Marlene Seide
Published: September 2017

As novas tecnologias e as redes sociais tornam-se para os idosos um espaço para a ressocialização e integração na sociedade contemporânea através de sua inserção no mundo virtual. Portanto, o principal objetivo desta pesquisa é analisar o comportamento e a utilização das redes sociais pelos idosos. Com aspectos metodológicos de natureza quantitativa, do tipo survey, foi desenvolvido um instrumento de coleta de dados estruturado. Participaram da pesquisa 191 idosos. Os dados foram analisados no software SPSS para o estabelecimento do ranking médio (RM) do grau de concordância dos respondentes. Constata-se que o principal motivo para a criação de uma rede social é para poder conversar com outras pessoas e a principal forma de utilização é para manter o contato com pessoas que moram longe, sendo estas, familiares ou amigos.
AVALIAÇÃO DA QUALIDADE DOS SERVIÇOS DO SETOR FINANCEIRO DE UMA UNIVERSIDADE: UMA ANÁLISE COMPARATIVA DA VISÃO DOS SERVIDORES PRESTADORES E DOS SERVIDORES USUÁRIOS DOS SERVIÇOS
Authors: Tolfo Silvana Dalmaso , Roth Henrique Schneider , Dias Vanessa Abreu , Luiz Gustavo De Carvalho
Published: September 2017

O estudo versa sobre a avaliação da qualidade dos serviços prestados no setor financeiro da Universidade Federal do Pampa, onde buscou-se efetuar uma comparação entre a percepção dos servidores lotados no setor e a visão dos servidores usuários dos serviços. Para tanto, o modelo utilizado foi baseado na SERVPERF adaptado para quatro dimensões e a pesquisa foi composta por duas fases: uma entrevista com quatro servidores do setor financeiro e um questionário enviado para os servidores docentes e técnicos administrativos usuários dos serviços do setor, do qual obteve-se 140 respostas válidas. Analisando os resultados, verificou-se que os serviços prestados no setor financeiro da Instituição galgou uma boa avaliação por parte dos usuários dos serviços, sendo que a discordância entre as percepções de servidores prestadores dos serviços e usuários limitaram-se a alguns pontos específicos.
PARTICIPAÇÃO POLÍTICA NAS REDES SOCIAIS: UM ESTUDO ENTRE JOVENS UNIVERSITÁRIOS
Authors: Dias Diana Leonardo , Doula Sheila Maria , Cardoso Poliana Oliveira
Published: September 2017

A expansão da internet com canais de comunicação mais rápidos e menos onerosos tem influenciado diretamente as relações sociais e políticas, o que por sua vez, tem propiciado novas formas de organização e ativismo. Nessa perspectiva, este artigo tem por objetivo compreender as representações juvenis a respeito da participação política mediada pelo uso das TICs. A metodologia inclui revisão bibliográfica e coleta de dados através da aplicação de questionários. Como resultado, destaca-se que a internet é entendida como um espaço público de contestações, debates, comunicação irrestrita, mobilizações, formação de opiniões, mas ao mesmo tempo se constitui como o local do comodismo e da falta de efetividade, demonstrando que finalidade seria de complementar as formas clássicas de participação, não substituí-las.
TRANSIÇÃO DEMOGRÁFICA E EDUCAÇÃO NO RIO GRANDE DO SUL: UM OLHAR PROSPECTIVO
Authors: Marion Filho Pascoal José , Vieira Cristiéle Almeida , Klimeck Keyla Alves
Published: September 2017

O artigo tem como objetivo avaliar os efeitos das mudanças na estrutura social das microrregiões do Rio Grande do Sul e verificar como elas afetaram o número de matrículas no passado e, possivelmente, afetarão no futuro. Esta é uma pesquisa descritiva com base em dados secundários e projeções do Instituto Brasileiro de Geografia e Estatística (IBGE) e da Fundação de Economia e Estatística (FEE). Os resultados mostram que o processo de transição demográfica é heterogêneo no Estado, pois 15 das 35 microrregiões apresentaram redução da população de 2000 para 2010. Constata-se também que a taxa de dependência total teve queda generalizada, explicada pela redução na taxa de dependência de jovens superior ao aumento na de idosos. Com relação a educação, houve uma redução na taxa de analfabetismo e de matrículas do ensino fundamental e médio, tanto no sistema público quanto no privado, enquanto o ensino superior teve comportamento oposto. Além disso, as projeções sinalizam uma queda constante da população em idade escolar em todos os níveis. Estima-se que a demanda por ensino médio terá a maior redução no período 2020-2050, seguida pela educação infantil, ensino fundamental final e ensino fundamental inicial.
SAÚDE BÁSICA EM PERNAMBUCO: ANTES E APÓS O PROGRAMA MAIS MÉDICOS
Authors: Silva Marcio Nunes da , Freitas Mauricio Assuero Lima de
Published: September 2017

Com o objetivo de melhorar as questões relacionadas com a assistência básica, dentre as quais a falta de médicos nas unidades hospitalares, principalmente no interior dos estados, o governo criou um programa denominado Mais Médicos, com foco no recrutamento de profissionais de diversas nacionalidades, para atendimento ambulatorial em pontos críticos. Nesse contexto, o objetivo deste trabalho foi evidenciar os impactos na saúde básica de Pernambuco após a implantação do Programa Mais Médicos (PMM). Os dados da pesquisa foramcoletados, no site do DATASUS, especificamente no que concernem as informações sobre o número de consultas, número de óbitos por causas evitáveis, número de internações e valores por serviços hospitalares. Foram realizados testes qui-quadrado e utilizado um modelo de regressão linear para inferir a relação entre o número de óbitos no Estado de Pernambuco (variável dependente) e o número de consultas (variável independente). Os resultados evidenciaram que apenas 26,59% das variações do número de óbitos são explicadas pelas variações da variável “número de consultas” e numa análise qualitativa mediante o uso de uma variável dummy, observou-se que não há diferença entre o valor esperado médio do número de óbitos antes e depois da adoção do programa. Pode-se inferir que a variável “número de consultas” foi estatisticamente significativa.
DOENÇA MENTAL E CONTROLE SOCIAL: RELEITURA A PARTIR DE MICHEL FOUCAULT
Authors: Rocha José Manuel de Sacadura
Published: September 2017

Este artigo foca o Controle Social por meio da denominada Doença Mental a partir primordialmente do pensamento de Michel Foucault. Explora a tradição antipsiquiátrica e da psicologia social de diversos autores do ponto de vista da Cultura nas sociedades industriais mercantis. Defende-se a ideia que o “relacionamento médico com a “forma psíquica” e seu tratamento estão na “conformação” que existe entre a economia política e as formas derivadas como o político” e sua manifestação pelo “poder”. Conclui-se que os sujeitos quando considerados doentios, quando tratados como perigosos, se inserem como agentes de mecanismos que visam ao controle biopolítico de suas energias psíquicas, estabelecendo um estilo de vida que vai além das relações de produção e consumo, mas vai por elas.
OS INDICADORES DE VIOLÊNCIA DOMÉSTICA CONTRA A MULHER NO MUNICÍPIO DE TRIUNFO
Authors: Souza Natasha Figueiró , Souza Marjane Bernardy
Published: September 2017

Este trabalho tem por objetivo investigar as denúncias de violência doméstica realizadas por mulheres no município de Triunfo, bem como os tipos de violência e se foram requeridas pelas vítimas as medidas protetivas de urgência. Foram encontrados 135 boletins de ocorrência relacionados à Lei 11.340/06, sendo 99 as medidas protetivas requeridas. Em relação aos tipos de violência, as denunciantes relataram 34,07% de violência física, 54,07% de violência psicológica, 2,22% de violência patrimonial, 8,88% de violência moral e nenhum caso de violência sexual. Considerado um dos municípios mais ricos do Rio Grande do Sul, Triunfo possui baixa qualidade de vida, evidente na falta de políticas públicas para as mulheres e contém quase 0,50% das denúncias de violência física e psicológica do Estado, valor expressivo para uma cidade com pouco mais de 12 mil mulheres. A violência é um fator de risco à saúde física, psíquica, emocional e social; o sofrimento psicológico afeta as esferas cognitivas, emocionais e comportamentais da vida das vítimas e pode desencadear transtornos do humor e de personalidade. Em relação à violência, ainda há muito para ser feito, as ações de prevenção devem ser conjuntas com políticas públicas, sociais e educacionais para motivar outras mulheres a realizarem a denúncia e saírem da situação de violência.
L’Ontario français et les grands congrès patriotiques canadiens-français (1883-1952)
Authors: Gervais Gaétan
Published: September 2017

Gaétan Gervais sonde les plus éloquentes traces de l’identité canadienne-française qu’il trouve intactes dans les mémoires des grands congrès patriotiques canadiens-français. Avec raison, il note que ces déploiements, qui se sont tenus entre 1883 et 1952, fournissent, sur l’Amérique française – dans ses expressions canadienne, franco-américaine et acadienne –, une richesse documentaire unique. Tout en commentant la participation franco-ontarienne à ces assises nationales, à caractère patriotique, religieux et linguistique, l’auteur relève une même unité de pensée, manifestée par une même symbolique, soutenue par la même armature institutionnelle, diffusant la même idéologie clérico-nationaliste et le même projet de société, parce que fondée sur le même sentiment profond d’appartenance au Canada français.
Transferts linguistiques et anglicisation des francophones. Les enjeux de l’exogamie au Canada
Authors: Bernard Roger
Published: September 2017

Roger Bernard approfondit ses recherches sur « les enjeux de l’exogamie » et la vulnérabilité des groupes minoritaires. À partir d’une compilation plus détaillée des données du recensement de 1991, il analyse les conséquences de ce phénomène sur les transferts linguistiques en englobant, dans son propos, les foyers mixtes francophones et les foyers mixtes anglophones. Cette nouvelle étude, qui prend en compte les groupes d’âges des épouses de langue maternelle française, lui permet de réviser et de nuancer les résultats obtenus dans son article précédent, et de faire les liens qui s’imposent entre exogamie et anglicisation : « plus le milieu est minoritaire, observe-t-il, plus les taux d’exogamie sont élevés, et plus les taux d’anglicisation des parents et des enfants sont élevés »; ce qui l’amène à l’évidence que l’exogamie est une cause majeure de l’anglicisation des minorités françaises au Canada.
Fréquentation scolaire, alphabétisation et société au Québec et en Ontario jusqu’en 1911 : les francophones et les autres
Authors: Ouellet Fernand
Published: September 2017

Tout en faisant une judicieuse critique des recensements de même que des interprétations de ses prédécesseurs, qu’il rectifie ou enrichit à l’occasion, Fernand Ouellet aborde un autre aspect de son projet de recherche en socio-économie des francophones du Canada : les rapports entre la fréquentation scolaire, l’alphabétisation et la société au Québec et en Ontario avant les années 1911. Ainsi, il observe, dès le début du xviie siècle, « la marche silencieuse vers la campagne et l’analphabétisme » qui se perpétuera, sous la mainmise du clergé, jusqu’aux législations de 1840, corrigeant sur ce point ceux qui continuent de répéter « que la dégradation de l’alphabétisme avait ses origines dans la conquête anglaise de 1760 ». C’est que les facteurs socio-économiques ont eu sur l’alphabétisation plus d’importance que les facteurs politiques. Son texte démontre qu’un système d’éducation, laissé aux mains d’une élite, ne fait que marginaliser ceux qui en sont exclus, en l’occurrence les femmes, les classes populaires et les habitants des campagnes. L’intervention de l’État tend à réduire ces inégalités sans pour autant les abolir.
Aux origines de l’identité franco-ontarienne
Authors: Gervais Gaétan
Published: September 2017

L’historien Gaétan Gervais, professeur à l’Université Laurentienne, analyse le problème de l’identité franco-ontarienne d’un point de vue contemporain. Il voit dans l’éclatement du Canada français, provoqué par la Révolution tranquille, la source du malaise identitaire des élites ontaroises actuelles. Exclus par un Québec qui récupère comme québécois tout l’héritage naguère canadien-français, avec l’encouragement d’organismes nationaux – l’auteur montre du doigt la Société Radio-Canada, dite « la SRC », et le Secrétariat d’État (Patrimoine canadien) – qui opposent les Québécois aux « francophones » canadiens, les Franco-Ontariens s’ontarianisent : le déplacement de leurs centres d’activités vers Sudbury et Toronto est en cela significatif.
« Le Lynx et le renard ». Un relais déroutant dans la transmission du conte populaire français en Ontario
Authors: Pichette Jean-Pierre
Published: September 2017

Son enquête sur « Le Lynx et le renard » amène Jean-Pierre Pichette, ethnologue de l’Université de Sudbury, à la démonstration de l’origine française d’un petit conte animalier recueilli chez les Sauteux du nord de l’Ontario, en dépit de son inculturation amérindienne. Par un curieux retour des choses, l’étudiant parti à la recherche de la culture de l’autre se retrouve plongé dans la sienne propre que le gros bon sens, nourri de préjugés – le mythe du « bon sauvage », dans sa version écologique contemporaine, joint au complexe du minoritaire –, l’empêche cependant de reconnaître. La privation de contact avec la tradition orale franco-canadienne rendrait ainsi, devant une simple présomption, l’identification impossible et, partant, l’abdication naturelle.
La Mémoire oubliée en Ontario français. « Désespoir de vieille fille » de Thérèse Tardif
Authors: Dorais Fernand
Published: September 2017

Fernand Dorais, professeur de littérature à la retraite de l’Université Laurentienne, a choisi pour son premier article – il annonce une trilogie – d’exhumer un essai publié à Ottawa en 1943 et, à son avis, injustement tombé dans l’oubli. Il s’agit de Désespoir de vieille fille de Thérèse Tardif, un livre qui choqua lors de sa parution et fit un tel scandale qu’il eut droit, la même année, à la Réponse à « Désespoir de vieille fille » de Simone Routier. C’est que Thérèse Tardif était la première femme « à parler de la part matérielle de l’amour ». À l’aide des recensions de l’époque, des articles de Tardif et des méthodes critiques, l’auteur propose une nouvelle lecture de cette oeuvre, « vraiment extraordinaire dans le Canada français de 1943 », qu’il situe dans le courant des écrivains catholiques français de son temps.
Le verbum interius du traducteur et la cristallisation du sens : la traçabilité du processus traduisant à travers les isotopies et les sciences cognitives
Authors: Stefanink Bernd , Bălăcescu Ioana
Published: September 2017

Nous nous sommes proposé dans ce travail de mettre en évidence le bien-fondé de certaines thèses qui sont à la base de l’approche herméneutique en traduction, mais ont donné lieu à des critiques de la part d’un certain nombre de traductologues qui, selon nous, font preuve d’une méconnaissance de cette approche. Dans la conclusion de la première synthèse des recherches en herméneutique traductive, Cercel (2013 : 364) déplore ce manque de compréhension dû, selon elle, à un manque d’explicitation de ces thèses de la part de ses représentants, qui s’en tiennent à des « plakative Aussagen » [déclarations abstraites]. Nous relevons ce défi d’explicitation en essayant d’établir le bien-fondé de ces thèses contestées, notamment celle que résume cette déclaration de Heidegger « Den Bedeutungen wachsen Worte zu » [les mots viennent aux significations] – et en illustrant des concepts comme la Leibhaftigkeit (Paepcke 1986) [corporéité] à l’aide d’un exemple pratique tiré de notre corpus d’herméneutique traductive. Nous utilisons l’analyse conversationnelle ethnométhodologique pour étudier la négociation du sens à traduire en ayant pour objectif de fournir des explications aux processus relationnels entre texte et traducteur. Nous nous basons, pour ce faire, sur des théories linguistiques (notamment le concept d’isotopie), ainsi que sur des recherches récentes en sciences cognitives. Notre exemple veut illustrer la thèse que le sens élaboré par le traducteur dans son mental se comporte comme le verbum interius tel que le conçoit Saint-Augustin.
Un estudio experimental sobre la adquisición de la competencia cultural en la formación de traductores. Resultados de un estudio piloto
Authors: Olalla-Soler Christian
Published: September 2017

En este artículo se presentan los principales resultados del estudio piloto de un estudio experimental sobre la adquisició de la competencia cultural en la formación de traductores. Este estudio se enmarca en la investigación sobre adquisición de la competencia traductora del Grupo PACTE (Proceso de Adquisición de la Competencia Traductora y Evaluación). El diseño experimental del estudio se pilotó con una muestra de cinco estudiantes con alemán como segunda lengua extranjera del último curso del Grado en Traducción e Interpretación de la Universitat Autònoma de Barcelona. La lengua materna de los estudiantes era el español o el catalán. Se recogieron datos para comprobar la adecuación de los criterios de selección de la muestra, la idoneidad de los problemas de traducción seleccionados para el análisis, el funcionamiento de los instrumentos de recogida de datos y la duración y el orden de las tareas experimentales. Los resultados han demostrado que los instrumentos recogen datos pertinentes, la muestra seleccionada era representativa de la población de estudio y los problemas de traducción eran útiles para el análisis. Sin embargo, las tareas experimentales deben ser revisadas y deben recogerse más datos sobre aspectos culturales.
Searching for the one
Authors: Groll Helga
Published: September 2017

The views of peers are important when applying for a faculty position, but so are research plans and being a good 'fit'. Many universities are also trying to reduce bias in their recruitment processes.
Intuition, Reflection and Reflexivity
Authors: Dankl Kathrina
Published: September 2017

This paper synthesises findings from a design method course that focused on a design brief in shared medical decision making. In the paper, design methods is a term describing any action undertaken for a forward movement in the design process. The course is based on a selection of assignments that target intuition, reflection and reflexivity. Although many science disciplines strive to include more elements of active and practice-based learning, design education faces the challenge of integrating theory in a ‘designerly’ way. The current curriculum offers little opportunity to train these skills together with traditional practice-based ones. However, the complexity of design tasks in interconnected systems with manifold stakeholders and users requires a cohesive design research approach to govern its inherent complexity. Using the findings of this case study, design students can integrate theory in their practical work and welcome the confrontation found in current design research literature, helping them contextualise the meaning of design, be inspired and develop an individual stance on the purpose of design.
Design Learning for Tomorrow
Authors: Scott Frisch Nina , Bergman Silje
Published: September 2017

This special issue of Form Akademisk consist of four selected peer reviewed articles developed from papers held at The 3rd International Conference for Design Education Researchers - DRS/CUMULUS learnxdesign conference held in Chicago from the 28th of June – 30th of June 2015.  The conference was implemented through close cooperation between the Design Research Society (DRS) and the International Association of Universities and Schools of Design, Art and Media (CUMULUS). It was hosted by School of the Art Institute of Chicago.
Multi-scale immunoepidemiological modeling of within-host and between-host HIV dynamics: systematic review of mathematical models
Authors: Dorratoltaj Nargesalsadat , Nikin-Beers Ryan , Ciupe Stanca M. , Eubank Stephen G. , Abbas Kaja M.
Published: September 2017

Objective

The objective of this study is to conduct a systematic review of multi-scale HIV immunoepidemiological models to improve our understanding of the synergistic impact between the HIV viral-immune dynamics at the individual level and HIV transmission dynamics at the population level.

Background

While within-host and between-host models of HIV dynamics have been well studied at a single scale, connecting the immunological and epidemiological scales through multi-scale models is an emerging method to infer the synergistic dynamics of HIV at the individual and population levels.

Methods

We reviewed nine articles using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework that focused on the synergistic dynamics of HIV immunoepidemiological models at the individual and population levels.

Results

HIV immunoepidemiological models simulate viral immune dynamics at the within-host scale and the epidemiological transmission dynamics at the between-host scale. They account for longitudinal changes in the immune viral dynamics of HIV+ individuals, and their corresponding impact on the transmission dynamics in the population. They are useful to analyze the dynamics of HIV super-infection, co-infection, drug resistance, evolution, and treatment in HIV+ individuals, and their impact on the epidemic pathways in the population. We illustrate the coupling mechanisms of the within-host and between-host scales, their mathematical implementation, and the clinical and public health problems that are appropriate for analysis using HIV immunoepidemiological models.

Conclusion

HIV immunoepidemiological models connect the within-host immune dynamics at the individual level and the epidemiological transmission dynamics at the population level. While multi-scale models add complexity over a single-scale model, they account for the time varying immune viral response of HIV+ individuals, and the corresponding impact on the time-varying risk of transmission of HIV+ individuals to other susceptibles in the population.
Paleomagnetic Constraints on the Middle Miocene‐Early Pliocene Stratigraphy in the Xining Basin, NE Tibetan Plateau, and the Geologic Implications
Authors: Yang Rongsheng , Fang Xiaomin , Meng Qingquan , Zan Jinbo , Zhang Weilin , Deng Tao , Yang Yibo , Ruan Xiaobai , Yang Liye , Li Bingshuai
Published: September 2017

The Xining Basin lies in the transitional zone between the arid Asian interior and the East Asian monsoon region. The continuous Cenozoic sediments in the basin provide a unique archive recording the uplift of the Tibetan Plateau and its environmental effects on central Asian aridification and Asian monsoon evolution. However, sediments deposited since the middle Middle Miocene have not been precisely dated, hindering our ability to address these issues. Here we dated a 336 m‐thick section containing many Late Miocene fossil mammals from the eastern basin. High‐resolution paleomagnetism revealed 16 normal and 16 reversed zones that correlate well with chrons 3n to 5Ar.1r of the Geomagnetic Polarity Time Scale, constraining the section to ∼12.7–4.8 Ma. The changes in lithofacies from floodplain to braided river at ∼8.6 Ma and to thick alluvial fan at ∼6.3 Ma with predominantly southerly paleocurrent directions occur simultaneously with an increase in the sedimentation rates, representing two periods of rapid uplift in the eastern Qilian Shan to the north. Our results provide a robust oldest age constraint (<4.8 Ma) on the ancient Huang Shui and Yellow River terraces on the basin sediments and eolian deposits on the terraces. The presence of well‐developed floodplain paleosols, shallow lake marls, and many large mammals in the lower section suggests that the monsoon climate in the late Middle Miocene to Late Miocene was more humid and stronger than that at present.
Spatially Variable CO2 Degassing in the Main Ethiopian Rift: Implications for Magma Storage, Volatile Transport, and Rift‐Related Emissions
Authors: Hunt Jonathan A. , Zafu Amdemichael , Mather Tamsin A. , Pyle David M. , Barry Peter H.
Published: September 2017

Deep carbon emissions from historically inactive volcanoes, hydrothermal, and tectonic structures are among the greatest unknowns in the long‐term (∼Myr) carbon cycle. Recent estimates of diffuse CO2 flux from the Eastern Rift of the East African Rift System (EARS) suggest this could equal emissions from the entire mid‐ocean ridge system. We report new CO2 surveys from the Main Ethiopian Rift (MER, northernmost EARS), and reassess the rift‐related CO2 flux. Since degassing in the MER is concentrated in discrete areas of volcanic and off‐edifice activity, characterization of such areas is important for extrapolation to a rift‐scale budget. Locations of hot springs and fumaroles along the rift show numerous geothermal areas away from volcanic edifices. With these new data, we estimate total CO2 emissions from the central and northern MER as 0.52–4.36 Mt yr−1. Our extrapolated flux from the Eastern Rift is 3.9–32.7 Mt yr−1 CO2, overlapping with lower end of the range presented in recent estimates. By scaling, we suggest that 6–18 Mt yr−1 CO2 flux can be accounted for by magmatic extension, which implies an important role for volatile‐enriched lithosphere, crustal assimilation, and/or additional magmatic intrusion to account for the upper range of flux estimates. Our results also have implications for the nature of volcanism in the MER. Many geothermal areas are found >10 km from the nearest volcanic center, suggesting ongoing hazards associated with regional volcanism.
Redistribution of Iron and Titanium in High‐Pressure Ultramafic Rocks
Authors: Crossley Rosalind J. , Evans Katy A. , Reddy Steven M. , Lester Gregory W.
Published: September 2017

The redox state of iron in high‐pressure serpentinites, which host a significant proportion of Fe3+ in subduction zones, can be used to provide an insight into iron cycling and constrain the composition of subduction zone fluids. In this study, we use oxide and silicate mineral textures, interpretation of mineral parageneses, mineral composition data, and whole rock geochemistry of high‐pressure retrogressed ultramafic rocks from the Zermatt‐Saas Zone to constrain the distribution of iron and titanium, and iron oxidation state. These data provide an insight on the oxidation state and composition of fluids at depth in subduction zones. Oxide minerals host the bulk of iron, particularly Fe3+. The increase in mode of magnetite and observation of magnetite within antigorite veins in the investigated ultramafic samples during initial retrogression is most consistent with oxidation of existing iron within the samples during the infiltration of an oxidizing fluid since it is difficult to reconcile addition of Fe3+ with the known limited solubility of this species. However, high Ti contents are not typical of serpentinites and also cannot be accounted for by simple mixing of a depleted mantle protolith with the nearby Allalin gabbro. Titanium‐rich phases coincide with prograde metamorphism and initial exhumation, implying the early seafloor and/or prograde addition and late mobilization of Ti. If Ti addition has occurred, then the introduction of Fe3+, also generally considered to be immobile, cannot be disregarded. We explore possible transport vectors for Ti and Fe through mineral texture analysis.
A Lagging Model for Describing Drawdown Induced by a Constant‐Rate Pumping in a Leaky Confined Aquifer
Authors: Lin Ye‐Chen , Yeh Hund‐Der
Published: September 2017

This study proposes a generalized Darcy's law with considering phase lags in both the water flux and drawdown gradient to develop a lagging flow model for describing drawdown induced by constant‐rate pumping (CRP) in a leaky confined aquifer. The present model has a mathematical formulation similar to the dual‐porosity model. The Laplace‐domain solution of the model with the effect of wellbore storage is derived by the Laplace transform method. The time‐domain solution for the case of neglecting the wellbore storage and well radius is developed by the use of Laplace transform and Weber transform. The results of sensitivity analysis based on the solution indicate that the drawdown is very sensitive to the change in each of the transmissivity and storativity. Also, a study for the lagging effect on the drawdown indicates that its influence is significant associated with the lag times. The present solution is also employed to analyze a data set taken from a CRP test conducted in a fractured aquifer in South Dakota, USA. The results show the prediction of this new solution with considering the phase lags has very good fit to the field data, especially at early pumping time. In addition, the phase lags seem to have a scale effect as indicated in the results. In other words, the lagging behavior is positively correlated with the observed distance in the Madison aquifer.
Interpreting Repeated Temperature‐Depth Profiles for Groundwater Flow
Authors: Bense Victor F. , Kurylyk Barret L. , van Daal Jonathan , van der Ploeg Martine J. , Carey Sean K.
Published: September 2017

Temperature can be used to trace groundwater flows due to thermal disturbances of subsurface advection. Prior hydrogeological studies that have used temperature‐depth profiles to estimate vertical groundwater fluxes have either ignored the influence of climate change by employing steady‐state analytical solutions or applied transient techniques to study temperature‐depth profiles recorded at only a single point in time. Transient analyses of a single profile are predicated on the accurate determination of an unknown profile at some time in the past to form the initial condition. In this study, we use both analytical solutions and a numerical model to demonstrate that boreholes with temperature‐depth profiles recorded at multiple times can be analyzed to either overcome the uncertainty associated with estimating unknown initial conditions or to form an additional check for the profile fitting. We further illustrate that the common approach of assuming a linear initial temperature‐depth profile can result in significant errors for groundwater flux estimates. Profiles obtained from a borehole in the Veluwe area, Netherlands in both 1978 and 2016 are analyzed for an illustrative example. Since many temperature‐depth profiles were collected in the late 1970s and 1980s, these previously profiled boreholes represent a significant and underexploited opportunity to obtain repeat measurements that can be used for similar analyses at other sites around the world.
Effect of Alkyl Chain Branching Point on 3D Crystallinity in High N‐Type Mobility Indolonaphthyridine Polymers
Authors: Fallon Kealan J. , Santala Annikki , Wijeyasinghe Nilushi , Manley Eric F. , Goodeal Niall , Leventis Anastasia , Freeman David M. E. , Al‐Hashimi Mohammed , Chen Lin X. , Marks Tobin J. , Anthopoulos Thomas D. , Bronstein Hugo
Published: September 2017

Herein, this study investigates the impact of branching‐point‐extended alkyl chains on the charge transport properties of three ultrahigh n‐type mobility conjugated polymers. Using grazing incidence wide‐angle X‐ray scattering, analysis of the crystallinity of the series shows that while π–π interactions are increased for all three polymers as expected, the impact of the side‐chain engineering on polymer backbone crystallinity is unique to each polymer and correlates to the observed changes in charge transport. With the three polymers exhibiting n‐type mobilities between 0.63 and 1.04 cm2 V−1 s−1, these results ratify that the indolonaphthyridine building block has an unprecedented intrinsic ability to furnish high‐performance n‐type organic semiconductors.
Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells
Authors: Liße Domenik , Monzel Cornelia , Vicario Chiara , Manzi John , Maurin Isabelle , Coppey Mathieu , Piehler Jacob , Dahan Maxime
Published: September 2017

Magnetogenetics is emerging as a novel approach for remote‐controlled manipulation of cellular functions in tissues and organisms with high spatial and temporal resolution. A critical, still challenging issue for these techniques is to conjugate target proteins with magnetic probes that can satisfy multiple colloidal and biofunctional constraints. Here, semisynthetic magnetic nanoparticles are tailored based on human ferritin coupled to monomeric enhanced green fluorescent protein (mEGFP) for magnetic manipulation of proteins inside living cells. This study demonstrates efficient delivery, intracellular stealth properties, and rapid subcellular targeting of those magnetic nanoparticles via GFP–nanobody interactions. By means of magnetic field gradients, rapid spatial reorganization in the cytosol of proteins captured to the nanoparticle surface is achieved. Moreover, exploiting efficient nanoparticle targeting to intracellular membranes, remote‐controlled arrest of mitochondrial dynamics using magnetic fields is demonstrated. The studies establish subcellular control of proteins and organelles with unprecedented spatial and temporal resolution, thus opening new prospects for magnetogenetic applications in fundamental cell biology and nanomedicine.
Selective CO2 Capture and High Proton Conductivity of a Functional Star‐of‐David Catenane Metal–Organic Framework
Authors: Huang You‐Gui , Wu Shu‐Qi , Deng Wei‐Hua , Xu Gang , Hu Fa‐Lu , Hill Jonathan P. , Wei Wei , Su Sheng‐Qun , Shrestha Lok Kumar , Sato Osamu , Wu Ming‐Yan , Hong Mao‐Chun , Ariga Katsuhiko
Published: September 2017

Network structures based on Star‐of‐David catenanes with multiple superior functionalities have been so far elusive, although numerous topologically interesting networks are synthesized. Here, a metal–organic framework featuring fused Star‐of‐David catenanes is reported. Two triangular metallacycles with opposite handedness are triply intertwined forming a Star‐of‐David catenane. Each catenane fuses with its six neighbors to generate a porous twofold intercatenated gyroid framework. The compound possesses exceptional stability and exhibits multiple functionalities including highly selective CO2 capture, high proton conductivity, and coexistence of slow magnetic relaxation and long‐range ordering.
Novel Multiferroic Phases and Phenomena in Epitaxial (111) BiFeO3 Films
Authors: Xu Changsong , Xiang Hongjun , Bellaiche Laurent
Published: September 2017

Multiferroics are attracting much interest because they simultaneously possess ordered electric and magnetic dipoles. In particular, numerous recent studies are devoted to find novel multiferroic phases, as, for example evidenced by the flurry of activities that accompanied the discovery of the so‐called T‐phase in BiFeO3 systems, when these latter are made in forms of (001) epitaxial films and subject to high‐enough compressive strains. Here it is predicted, via the combined use of a genetic algorithm and first‐principles calculations, that novel multiferroic phases, as well as new phenomena, can also occur in epitaxial BiFeO3 films, but when grown along the less conventional [111] direction and when experiencing large enough tensile strains. One example includes the hexagonal YMnO3‐type P63cm phase, that exhibits an anomalous behavior for its out‐of‐plane electric polarization and that can also undergo magnetic transitions when varying the tensile strain. Another striking example is the emergence of an unusual crystal structure of triclinic symmetry, that possesses controllable polarization's direction as well as magnetic spiral structures whose characteristics (e.g., periodicity and propagation direction) can be altered by epitaxial strain. Such findings may open new ways to design multiferroics and novel devices exploiting their cross‐coupling between electric and magnetic properties.
Lower Order and Higher Order Entanglement in Four‐Wave Mixing Process
Authors: Das Moumita , Sen Biswajit , Ray Ayan , Pathak Anirban
Published: September 2017

Possibilities of generation of lower order and higher order intermodal entanglement in four‐wave mixing (FWM) process are rigorously investigated using Sen‐Mandal perturbative technique. The investigation has revealed that for a set of experimentally realizable parameters, one can observe lower order and higher order intermodal entanglement between pump and signal modes and signal and idler modes in a FWM process. In addition, trimodal entanglement involving pump, signal and idler modes is also reported.
Enantioselective Synthesis of Tetrahydropyrano[3,4‐b]indoles: Palladium(II)‐Catalyzed Aminopalladation/1,4‐Addition Sequence
Authors: Chen Junjie , Han Xiuling , Lu Xiyan
Published: September 2017

A novel palladium(II)‐catalyzed cyclization of aniline‐tethered alkynyl cyclohexadienones is reported. This reaction offers an atom‐economical and redox‐neutral access to various cyclohexenone‐fused tetrahydropyrano[3,4‐b]indoles with high yield and excellent enantioselectivity. Remarkably, this work represents the first example on a transition‐metal‐catalyzed asymmetric intramolecular aminopalladation/1,4 addition sequence.
Facile Synthesis of Lanthanide (Ce, Eu, Tb, Ce/Tb, Yb/Er, Yb/Ho, and Yb/Tm)‐Doped LnF3 and LnOF Porous Sub‐Microspheres with Multicolor Emissions
Authors: Zhao Shuang , Shao Baiqi , Feng Yang , Yuan Senwen , Huo Jiansheng , Lü Wei , Liu Kai , You Hongpeng
Published: September 2017

Monodisperse YF3 and YOF porous sub‐microspheres were synthesized by using a novel sacrificing template method with amorphous Y(OH)CO3⋅x H2O as the precursors and the template. It was found that the size and shape were well maintained, and the condensed precursor was transformed into uniform porous structures after fluoridation. By fine‐tuning the feed of the fluorine source, the final product could be converted from YF3 to YOF. A possible growth mechanism is proposed for the uniform porous YF3 structure and the porous yolk–shell‐like YOF structure. The luminescence properties showed that the as‐synthesized YF3:Ln3+ (Ln=Eu, Tb, Ce, Ce/Tb, Yb/Er, Yb/Ho, and Yb/Tm) products exhibited strong multicolor emissions, which included down‐/upconversion and energy‐transfer processes. Additionally, YOX (X=Cl and Br) could be obtained if a different halogen source was used during calcination. However, the spheres were almost completely destroyed. Our novel synthetic route can also be extended to other lanthanide fluorides (REF3, RE=Gd, Lu), which may open a facile way to fabricate novel porous nanostructures.
Nonlinear Adaptive Model Predictive Control of Constrained Systems with Offset‐Free Tracking Behavior
Authors: Vatankhah Bahareh , Farrokhi Mohammad
Published: September 2017

In this paper, a nonlinear model‐based predictive control strategy for constrained systems based on an adaptive neural network (NN) predictor is proposed. The proposed controller is robust against the model uncertainties and external bounded disturbances. Moreover, it provides offset‐free tracking behavior using the adaptive structure in the model. Based on the uncertainties bounds, the restriction of the system constraints causes robust feasibility and stability of the closed‐loop system. It is shown that the output of the NN predictor converges to the system output. Moreover, offset‐free behavior of the closed‐loop system is investigated using the Lyapunov theorem. Simulation results show the effectiveness of the proposed method as compared to the recently proposed model predictive control methods in the literature.
The Other Face of an Editor: ADAR1 Functions in Editing‐Independent Ways
Authors: Licht Konstantin , Jantsch Michael F.
Published: September 2017

The RNA editing enzyme ADAR1 seemingly has more functions besides RNA editing. Mouse models lacking ADAR1 and sensors of foreign RNA show that RNA editing by ADAR1 plays a crucial role in the innate immune response. Still, RNA editing alone cannot explain all observed phenotypes. Thus, additional roles for ADAR1 must exist. Binding of ADAR1 to RNA is independent of its RNA editing function. Thus, ADAR1 may compete with other RNA‐binding proteins. A very recent manuscript elaborates on this and reports competition of ADAR1 with STAUFEN1, thereby modulating RNA‐degradation. ADAR1 is also known to recruit proteins such as DROSHA to nascent transcripts. Still, many open questions remain. For instance, the biological role of the Z‐DNA binding domains in ADAR1 is not defined. Moreover, the impact of ADAR1 on the RNA‐folding landscape is unclear. In sum, moonlighting functions of ADAR1 may be manifold and have a great impact on the transcriptome.
Application of microscope‐based scanning software (Panoptiq) for the interpretation of cervicovaginal cytology specimens
Authors: Groen Ruben , Abe Kuniko , Yoon Han‐Seung , Li Zaibo , Shen Rulong , Yoshikawa Akira , Nitanda Takao , Shimizu Yukiko , Otsuka Isao , Fukuoka Junya
Published: September 2017

BACKGROUND

Digital pathology increasingly has been gaining the attention of pathologists worldwide. However, the application of digital cytology by Panoptiq (ViewsIQ, Vancouver, Canada) microscope‐based scanning software is relatively unexplored. Panoptiq enables the operator to combine low‐power panoramic digital images with z‐stacks at regions of interest with a significantly smaller image size than that obtained by whole‐slide scanning. The current study aimed to evaluate the feasibility of the use of Panoptiq in the digital interpretation of cervicovaginal cytology specimens in comparison with conventional light microscopy.

METHODS

A total of 100 liquid‐based cytology slides were selected sequentially. The dotted slides were reviewed and scanned, in which all dotted areas were scanned further by the ×20 objective with z‐stacks. The cases were reviewed by 4 pathologists and a cytotechnologist using conventional light microscopy and digital cytology images acquired by Panoptiq and interpreted based on the Bethesda classification system. The washout time was set as 3 weeks. The Cohen kappa coefficient was calculated to measure the agreement between the 2 modalities.

RESULTS

Digital cytology demonstrated an intermodality agreement among 3 observers who had sufficient training in digital pathology at concordance rates between 81% and 90% with kappa values between 0.76 and 0.86, whereas the other 2 observers who did not have sufficient training in digital pathology had lower agreement at a concordance rate of between 56% and 57%, with kappa values between 0.41 and 0.44.

CONCLUSIONS

Panoptiq appears to be feasible for the interpretation of cervicovaginal cytology specimens but requires adequate training in digital pathology. Cancer Cytopathol 2017;125:918‐25. © 2017 American Cancer Society.
Anti‐IL‐23 and Anti‐IL‐17 Biologic Agents for the Treatment of Immune‐Mediated Inflammatory Conditions
Authors: Frieder Jillian , Kivelevitch Dario , Haugh Isabel , Watson Ian , Menter Alan
Published: September 2017

Advancements in the immunopathogenesis of psoriasis have identified interleukin (IL)‐23 and IL‐17 as fundamental contributors in the immune pathways of the disease. Leveraging these promising therapeutic targets has led to the emergence of a number of anti‐IL‐23 and ‐17 biologic agents with the potential to treat multiple conditions with common underlying pathology. The unprecedented clinical efficacy of these agents in the treatment of psoriasis has paved way for their evaluation in diseases such as psoriatic arthritis, Crohn's disease, rheumatoid arthritis, in addition to other immune‐mediated conditions. Here we review the IL‐23/IL‐17 immune pathways and discuss the key clinical and safety data of the anti‐IL‐23 and anti‐IL‐17 biologic agents in psoriasis and other immune‐mediated diseases.
Superconducting Tin Selenide/Niobium Diselenide Ferecrystals†
Authors: Grosse Corinna , Alemayehu Matti B. , Mogilatenko Anna , Chiatti Olivio , Johnson David C. , Fischer Saskia F.
Published: September 2017

X‐ray diffraction, electron diffraction and scanning transmission electron microscopy images prove the structurally independent two‐dimensional layers of precisely m tin selenide bilayers and a single niobium diselenide trilayer in heterostructure thin films with a rotational disorder between them. The superconducting critical temperatures decrease systematically as m, the number of tin selenide layers, increases. However, all are lower than that known for isolated single niobium diselenide layers. This indicates a decoupling of these layers. A possible mechanism is a decrease in the density of states due to charge donation from the tin selenide layer.
Pretreatment Effect on Ceria‐Supported Gold Nanocatalysts for CO Oxidation: Importance of the Gold–Ceria Interaction
Authors: Ren Yuqing , Tang Ke , Wei Jingjing , Yang Hongxiao , Wei Huiying , Yang Yanzhao
Published: September 2017

The encapsulated Au/CeO2 hollow composite shows the effects of different pretreatment conditions on CO oxidation, showing complete conversion temperatures for CO in the order O2 pretreatment (T100=74 °C)>N2 pretreatment (T100=142 °C)>CO pretreatment (T100=167 °C). Because of the good confinement provided by the uniform pores of as‐prepared CeO2, the size of deposited Au nanoparticles embedded in the pores of CeO2 can be well controlled. Pretreated Au/CeO2 catalysts have a good stability with no clear deactivation even after 70 h. A systematic characterization was performed by employing various techniques (XRD, H2 temperature‐programmed reduction, scanning transmission electron microscopy with energy‐dispersive spectroscopy, Raman spectroscopy, X‐ray photoelectron spectroscopy, and in situ diffuse reflectance infrared Fourier transform spectroscopy) to understand the importance of the Au–CeO2 interaction. This revealed that the O2 pretreatment may result in (a) the migration of lattice oxygen atoms to the surface region and clearly increased number of oxygen vacancies in CeO2; (b) the increase of Au−Ox and Au−Ox−Ce bond lengths; (c) the creation of electron holes in the CeO2 substrate and electron deficiencies in Au nanoparticles as well as a strong Au–CeO2 interaction; and (d) increased number of bicarbonates on the surface and Auδ+−CO bonds were produced during CO oxidation. All these features are responsible for an overall enhanced activity of CO oxidation and high durability of the Au/CeO2 hollow composite.