bluuebunny/crossref_metadata_2025 huggingface dataset:
SRINGARA AND KARUNA RASAS IN THE SECRET OF THE NAGAS
Authors: Joshi Jagdish , Vaishnav Saurabh
Published: November 2020

Rasa is the emotional element in the theme or plot which falls into an
organised pattern. Rasa emotionally connects the observer to a work of art. The
more emotional connection of the reader to a work of art, the better the production of
rasa. Rasa is an experience first felt by the creator of the art, and secondly the
experience of the reader who receives the art. The creator seeks a medium to
express his feelings. The reader or observer then obtains the same emotion through
the medium that the creator selected and hence experiences the emotion felt by the
creator. Thus, the feeling of ‘rasa’ which is created by the creator is then re-created
by the reader. The extent the reader experiences the emotion which was earlier felt
by the creator depends on the aesthetic sense the reader possesses and the
intelligence of the creator in producing it. Rasa has been a prolific theory contributed
by Bharata Muni in the field of Indian Aesthetics. The paper analyses the dominance
of Sringara and Karuna rasas in The Secret of the Nagas.
Potential of Micro-Vortex Generators in Enhancing the Quality of Flow in a Hypersonic Inlet-Isolator
Authors: Che Idris Azam , Saad Mohd Rashdan , Kontis Konstantinos
Published: November 2020

The rush to be the first to demonstrate a practical hypersonic cruise missile has never been more frantic among the world’s superpowers, especially since China and India have also announced their own programme. The main hurdle for safe hypersonic flight is the severe shock wave-boundary layer interaction (SWBLI) that could induce flow separation. The separation could lead to inlet unstart and also structural damage at the flow re-attachment point. The simplest method to control these phenomena is by using passive flow control devices such as micro-vortex generator (MVG). The MVG is typically sized in the range of sub-boundary layer and the vortex generated can induce an early transition to turbulence thus avoiding or reducing the impact of flow separation. Many studies have been published with regard to MVG, but most were done in low supersonic speed and not in the hypersonic flow regime. In the current study, the MVG array was placed strategically at various locations on a hypersonic inlet-isolator representative geometry. The MVG has been proven to be very effective in eliminating or reducing the size of flow separation thus reducing the associated peak pressure at the re-attachment point.
Screening of Anxiolytic and Antidepressant of Methanolic Leaves Extract of Syzygium Cumini in Mice
Authors: Rehman Ahad Abdul , Riaz Azra , Asghar Muhammad Arif , Sikandar Bushra , Baig Moona
Published: November 2020

Background: Anxiety and depression are very common in clinical practice and reduce the overall quality of life. In recent years, various researchers have focused on natural products which are derived from medicinal plants. Studies suggested that diet rich in flavonoids, vitamins and antioxidants are the important components in reduction of anxiety and depression.

Objective: Hence current investigation was aimed to assess the anxiolytic and antidepressant effects of Syzygium cumini in mice at 125, 250 and 500 mg/kg.

Methods: These effects were mainly evaluated twice at 8th and 15th days by elevated plus maze, open field test, forced swimming test and tail suspension test.

Results and Conclusion: In open field test S. cumini showed escalation rearing in numbers and its duration which indicates improved exploratory behavior and locomotor activity of the animals. In EPM, there was increase in entries numbers and time spent in open arm. Decrease in immobility duration observed at low dose while high dose increased immobility duration in FST. Hence outcomes of current study indicate that S. cumini have anxiolytic and anti-depressant effect.
What is New in COVID-19 and What We Need to Do Against This Pandemic Infection? A Comparative Review
Authors: Naeem Sadaf , Shafiq Yousra , Asghar Muhammad Arif
Published: November 2020

Background: Initially, large number of COVID-19 cases reported from Wuhan City, China, reflected that this is likely the zoonotic origin of COVID-19. In March, 2020; it has since been declared a serious pandemic infection by the World Health Organization (WHO). 

Objective: The main objective of this review was to addressed what gaps still exist. Many researchers have reported the many common characteristics of COVID-19 virus in comparison with other pandemic viruses, while the major differences are discussed in this review.

Method: In this review, we investigated the general characteristics of COVID-19 its diagnosis and other preventive measures in comparison with other pandemic viruses that we know or we need to know.

Results: All reported corona viruses belong to the one genus and family Coronavirus and Coronaviridae. The COVID-19 virus spreads easily and exponentially multiple times compares to other viruses. It can be divided into four antigenic groups, HKU1, NL63, 229E and OC43. The case mortality rate of this pandemic is 1.68%, compared to other pandemics in their first outbreaks, including the great pandemic influenza (0.2%), SARS-CoV (10%), MERS-CoV (34%), and Ebola (50%). Laboratory findings related to COVID-19 include elevated levels of D-dimer, Alanine transaminase (ALT), LDH (lactate dehydrogenase), C-reactive protein (CRP), creatine kinase and prothrombin times.

Conclusion: This comparison based review will help to understand the biology, potential risk and preventive measures of COVID-19 and provide cognizance about what we need to do against this pandemic which victimized more than 200 countries up to the present time.
RİSÂLETÜ’N-NUSHİYYE’DE Kİ / KİM BAĞLAÇLARININ KULLANILIŞI
Authors: ÇAL Ahmet
Published: November 2020

Türkçe temel yapısı bakımından bağlaçlara pek elverişli bir dil değildir. Yardımcı cümlelerin kuruluşunda kullanılan bağlaçlar, Türklerin ilk karşılaştıkları milletlerin dillerinden alınarak Türkçeye aktarılmıştır. Türkçede eskiden beri var olan kaçan, kayru, kim, ne gibi kelimelere yabancı dillerdeki yardımcı cümleleri bağlamak için yeni anlamlar verilmiştir. Türkçenin çeşitli şartlar altında başka dil ve kültürlerin etkisinde kalması Türkçeye birtakım bağlaçların girmesine de yol açmıştır. Özellikle İslamiyet’in kabulünden sonra Türkçeye, Arapça ve Farsçadan bazı edat ve bağlaçların girdiği görülmektedir. Bu bağlaçlardan biri de Farsçadan dilimize girmiş olan ki bağlacıdır. Özellikle Eski Anadolu Türkçesi döneminde sıkça kullanılan ki bağlacı genellikle pekiştirme, kuvvetlendirme, sebep-sonuç, açıklama vs. fonksiyonlar üstlenerek yardımcı cümle ile temel cümle arasında bağlantı kurmuştur. Eski Türkçeden beri Türkçenin her döneminde kullanılan kim soru zamiri, ki’nin etkisiyle Eski Anadolu Türkçesi döneminde soru zamiri işlevinin yanında bağlaç fonksiyonu da kazanmıştır.

Bu çalışmada XIII. ve XIV. yüzyıl edebiyatının en güzel mesnevi örneklerinden biri olan Risâletü’n-Nushiyye adlı eserdeki ki ve kim bağlaçlarının kullanımı ve işlevleri üzerinde durulacaktır.
Milgram-kísérlet honvédekkel: a Nyugati Megszálló Csoport közreműködése a holokausztban
Authors: Ungváry Krisztián
Published: November 2020

The author provides an overview of how Hungarian forces became mass murderers in Ukraine in WWII.
Golyósirónírások és bélyegzőlenyomatok vonalkereszteződéseinek vizsgálati lehetősége
Authors: Göblyös Imre
Published: November 2020

The author provides an overview of how testing equipment and methods can be used in analyzing solvent ink.
Electrical conductivity of YBa2Cu3O7-δ single crystals under conditions of anionic ordering in Cu(1)O1-δ layers
Authors: Kalanda Nikolay A.
Published: November 2020

The influence of thermocycling annealing processes on the oxygen ordering degree (order parameter) in YBa2Cu3O7-δ single crystals has been studied. It has been shown that an increase in the critical onset temperature of the transition to the superconducting state during thermocycling annealing procedures is consistent with the decrease of the σс/σаb parameter. This fact indicates a redistribution of the electronic density between the structurally inhomogeneous Cu(2)O2 and Cu(1)O1-δ planes, due to the formation of oxygen long-range order in the O(4)–Cu(1)–O(4) linear groups along the (b) crystal structure axis of the unit cell, and elimination of oxygen defects in the square nets of the Cu(2)O2 planes. The existence of the critical value of the conductivity anisotropy σс/σаb, below which its behavior does not correlate with the change of Тс, has been confirmed. In this case an increase in Тс and orthorhombic distortion of the crystal structure during isothermal annealing are caused by the amplification of the “interlayer” interaction between the Cu(2)О2 and Cu(1)О1-δ planes. As a result, the contribution of the Cu(1)О1-δ chain layers to the electron state density at the Fermi level increases. These layers can acquire superconducting properties due to tunneling of Cooper pairs from the Cu(2)О2 planes resulting in the formation of the induced superconductivity in these planes.
Mumbai, Delhi : deux avatars indiens de la démocratie urbaine
Authors: Tawa Lama Stéphanie , Noûs Camille
Published: November 2020

Dans la démocratie indienne, la ville a longtemps été une catégorie mineure sinon inexistante. Mais si les institutions de la démocratie urbaine restent faibles aujourd’hui, les grandes villes indiennes sont le lieu et l’objet de pratiques politiques qui constituent autant de revendications en actes d’un droit à la ville. Deux mégapoles sont à cet égard particulièrement intéressantes. Mumbai et Delhi sont respectivement le berceau de deux partis politiques exceptionnels dans le paysage national : essentiellement urbains, ils allient une puissance locale de mobilisation, appuyée sur des pratiques originales, avec un discours politique qui résonne au niveau national. L’article s’attachera ainsi à comparer les discours et les pratiques de la Shiv Sena (Armée de Shivaji), parti régionaliste hindou à Mumbai, et ceux de l’Aam Aadmi Party (Parti de l’homme ordinaire), formation néo-gandhienne à Delhi. Nous montrerons comment ces deux partis définissent (de manière plus ou moins explicite), à travers la figure du citadin légitime, deux modèles contrastés de citoyenneté urbaine
“Cafés instead of seminar rooms"
Authors: Sennett Richard , von Busekist Astrid
Published: November 2020

Conversation avec Richard Sennett sur son parcours intellectuel à l’occasion de la parution de Bâtir et Habiter (trad. fr. Astrid von Busekist, Albin Michel, 2019), où l’auteur précise le sens de son engagement pour une ville ouverte.
Conceptualiser l’âgisme à partir du sexisme et du racisme
Authors: Rennes Juliette
Published: November 2020

Cet article explore le développement, depuis les années 1970, d’un cadre commun pour penser l’âgisme, le sexisme et le racisme. Il défend l’idée que les emprunts aux travaux sur les catégorisations hiérarchisées fondées sur le genre et la race ont été heuristiques pour comprendre et dénaturaliser celles fondées sur l’âge. Puis, il montre que les relations d’âge ne peuvent en revanche être pensées à travers le cadre matérialiste d’analyse des rapports de genre et de racisation, construit sur le modèle des rapports de classe. L’article plaide néanmoins pour une prise en considération de ces rapports, dans une perspective non pas tant analogique qu’intersectionnelle, afin d’analyser plus précisément qui sont, sociologiquement, les bénéficiaires et les victimes de l’âgisme.
Les politiques publiques façonnent-elles les listes électorales ?
Authors: Baudot Pierre-Yves , Bouquet Marie-Victoire , Braconnier Céline , Gabalda Ghislain
Published: November 2020

Cet article présente les résultats de la première enquête statistique menée en France sur la participation politique des personnes handicapées. En croisant les données collectées dans les dossiers individuels d’un échantillon aléatoire d’administrés de trois maisons départementales de personnes handicapées (MDPH), d’une part, et dans les registres électoraux d’inscription et d’émargement, d’autre part, nous analysons la façon dont les situations de handicap, que nous décrivons à partir des relations à l’administration qu’elles impliquent, conditionnent l’accès à la citoyenneté politique. Nous montrons que c’est au stade de l’inscription que se creuse le fossé de la participation politique, surtout pour les individus les plus encadrés, et expliquons comment l’intensité et la forme de cet encadrement déterminent le niveau de l’exclusion électorale.
Pour une sociohistoire de l’État régulateur européen
Authors: Avril Lola
Published: November 2020

Le champ politico-administratif européen qui se structure progressivement après la signature des traités de Rome, s’il prend des modalités inédites, n’en demeure pas moins l’héritier des compromis constitutionnels négociés historiquement dans les États membres. Dans la pratique quotidienne de ce gouvernement administratif de l’Europe, l’État européen connaît des reconfigurations importantes qui aboutissent dans les années 1980 à l’affirmation d’un État régulateur. Le présent article explore le glissement d’une gouvernementalité administrative à une gouvernementalité régulatrice, en interrogeant son assise sociale et professionnelle.
Aplicación terapéutica de nanodispositivos (medicamentos inteligentes) para la prevención y remediación de enfermedades cardiovasculares
Authors:   ESM-IPN, Vélez Reséndiz Juan Manuel , Vélez Arvízu Juan Jesús ,   Facultad de Ciencias, UNAM
Published: November 2020

Actualmente las enfermedades cardiovasculares representan la principal causa de morbimortalidad en el mundo; la aplicación de la nanotecnología es una gran promesa para su prevención y tratamiento. Actualmente se están desarrollando nanodispositivos para la liberación dirigida y controlada de medicamentos en sitios específicos en el organismo, por ejemplo, en células, tejidos, vasos sanguíneos y el corazón, así como para su diagnóstico, detección temprana de enfermedades cardiovasculares y tratamiento individualizado de pacientes. Otra aplicación de los nanodispositivos es la liberación de fármacos para corregir el mal acoplamiento de proteínas defectuosas. Con potentes superefectos, las nanopartículas deben ser capaces de provocar efectos terapéuticos a bajas dosis en periodos prolongados. La fabricación de nanodispositivos y nanoacarreadores deberá llevarse a cabo con un enfoque integral que tome en cuenta las propiedades generales, con la finalidad de evaluar la biocompatibilidad y, en consecuencia, evitar efectos adversos y tóxicos. La investigación intensificada en este campo ayudará a disminuir significativamente la morbimortalidad provocada por las enfermedades cardiovasculares. El presente trabajo incluye una sinopsis que describe algunos de los avances más recientes, relevantes y comunes de la nanomedicina en las ECV.
Aplicación de hidróxidos laminares de Ni, Fe y Co para la conversión de energía: Hidrólisis del agua
Authors:   Instituto Politécnico Nacional-ESIQIE-SEPI-DIQI-LiMpCa-QuF, UPALM, Guzmán Vargas Ariel , Vázquez Samperio Juvencio ,   Instituto Politécnico Nacional-ESIQIE-SEPI-DIQI-LiMpCa-QuF, UPALM, Martínez Ortiz María de J. ,   Instituto Politécnico Nacional-ESIQIE-SEPI-DIQI-LiMpCa-QuF, UPALM, Oliver Tolentino Miguel A. ,   Instituto Politécnico Nacional-ESIQIE-SEPI-DIQI-LiMpCa-QuF, UPALM
Published: November 2020

El avance tecnológico requiere de materiales que tengan un impacto directo en la vida cotidiana. Así, el desarrollo y aplicación de sistemas más eficientes, sustentables y por lo tanto no agresivos con el ambiente son un reto para la comunidad científica al involucrar diferentes disciplinas en la búsqueda de lograr el control de las propiedades a nivel nanométrico. En particular, los materiales multi-hidróxidos laminares, comúnmente conocidos como HDL, brindan un panorama prometedor ya que sus propiedades y composición pueden ser moduladas desde la síntesis, para una amplia gama de usos y aplicaciones. Recientemente, en áreas muy diferentes las aplicaciones de estos materiales han sido exploradas; por ejemplo: magnetismo, reacciones de producción de energía (electrocatalizadores), sensores electroquímicos, sistemas portadores-liberadores de fármacos, representan áreas de oportunidad. Por otra parte, sistemas en bajas dimensiones, la obtención de nanoláminas o nanohojas (nanosheets) a partir de la exfoliación de estos nanomateriales: nanopelículas multicapa, nanocompósitos y estructuras core-shell. La presente propuesta pretende desarrollar materiales tipo HDL multicatiónicos involucrando aspectos desde la concepción, síntesis y aplicación en la electrólisis del agua, proceso fundamental en la producción de hidrógeno, como fuente de energía renovable y una alternativa de las fuentes de energías tradicionales generadoras de contaminantes.
Primus Lessiak in koroški plebiscit leta 1920: o nekaterih malo znanih biografskih vidikih jezikoslovca
Authors: Bergmann Hubert
Published: November 2020

Prispevek se ukvarja z znanim koroškim germanistom Primusom Lessiakom (1878–1937) in z njegovo vlogo pred koroškim plebiscitom leta 1920. Pri tem obravnava družinsko okolje Lessiaka, ki je najverjetneje zrastel v dveh deželnih jezikih – nemščini in slovenščini. S propagandističnimi pesmimi, ki jih je pred pred plebiscitom (anonimno) objavil v nemškem in slovenskem narečju, si je prizadeval, da bi Južna Koroška ostala v Avstriji.
Современные практики оценки специальных текстов: лингвистическая и терминографическая экспертизы
Authors: Татьяна Петрова [Tat’jana Petrova]
Published: November 2020

V tem članku so analizirane sodobne prakse vrednotenja posebnih besedil – jezikovni pregled in pregled terminoloških slovarjev. Predmeti jezikovne preučitve in pregleda so se izkazali kot posebna besedila. Jezikovna in terminografska ekspertiza sta enakovredni, vendar ne identični ocenjevalni praksi, čeprav imata tudi skupne značilnosti.
Contrats de communication et entretiens d’orientation, dispositifs clinique ou psychosocial ?
Authors: Chabrol Claude
Published: November 2020

Cet article aborde la question de l’entretien d’orientation dans une perspective psycho-sociologie. On y défend le point de vue selon lequel les techniques d’entretien clinique, centrées sur la personne, ne sont pas appropriées aux objectifs du conseil en orientation. On suggère plutôt la mise en place de lieux de parole intra-groupe et inter-groupes, complété par des modules d’apprentissage socio-cognitifs pour développer les habiletés mentales et les stratégies de décision requises.
Cadres et formes identitaires - Vicariantes et pratiques en orientation
Authors: Guichard Jean
Published: November 2020

Le vingtième siècle a été marqué par un foisonnement conceptuel relatif à l’individu, au « soi », à « l’identité », etc. Au moins six grands courants de pensée peuvent être distingués. Certains d’entre eux relèvent le rôle des structures sociales ou des interactions ou d’interlocutions dans la formation de la « subjectivité » alors que d’autres se centrent beaucoup plus sur le « sujet » en tant que tel. Le modèle des cadres et des formes identitaires vicariantes se propose d’intégrer ces différentes approches. Il distingue les cadres identitaires (schémas cognitifs relatifs aux catégories de personnes que l’expérience sociale conduit les membres d’une société à concevoir) et les formes identitaires (dans lesquelles ceux-ci perçoivent autrui et se construisent). Ce modèle postule que ces cadres forment un système cognitif. Il pose que les formes identitaires subjectives (dans lesquelles les individus se construisent) sont susceptibles de vicariance : elles dépendent notamment des contextes où l’individu interagit (de ses interactions et interlocutions). La subjectivité (l’identité) est ainsi conçue comme le système unifié et structuré des formes identitaires dans lesquels l’individu se construit et se représente. La stabilité ou la malléabilité du soi dépendent ainsi des degrés (l) de développement de la société et (2) d’intégration des différents domaines du cosmos social ainsi que de la variété des interactions contextualisées dans lesquelles le sujet s’engage. Plusieurs validations indirectes de ces hypothèses sont proposées. Elles permettent de comprendre le rôle que les interlocutions jouent dans la construction de soi, lors d’interactions de conseil. Elles conduisent à s’interroger sur les finalités et les objectifs des pratiques en orientation.
Recent Advances on Measuring and Modeling ELF-Radiated Emissions for Space Applications
Authors: Nikolopoulos Christos D.
Published: November 2020

Nowadays, a wide range of space missions accommodate ever-stricter electromagnetic cleanliness requirements arising either from the need for more precise measurements or from the implementation of highly sensitive equipment. Therefore, the establishment of a methodology that ensures the minimization of the electric and/or magnetic field in specific areas inside or outside the spacecraft structure is crucial. Towards this goal, the current chapter proposes that utilizing the results of a process completed during the early design stages of a mission, that is, the measurement and characterization of each implemented device, the desired elimination of the field can be achieved. In particular, the emerged electromagnetic signatures of the units are proven essential for the proposed methodology, which, using a heuristic approach, defines the optimal ordinance of the equipment that leads to system-level electromagnetic field minimization in the volume of interest. The dimensions of the devices and the effect of the conductive surfaces of the spacecraft's hull are also taken into account.
Electromagnetic Compatibility Testing for Space Systems
Authors: Papastamatis Panagiotis K. , Nicolopoulou Eleni P. , Gonos Ioannis F.
Published: November 2020

Electromagnetic compatibility has emerged in the last decades as one of the most important aspects of product design. Space equipment, in particular, due to their increased sensitivity requirements and a greater risk of failure, are required to comply with a variety of EMC requirements. The scope of this chapter is to provide a detailed overview of these requirements according to the two main standards applicable, MIL-STD461G and ECSS-E-ST-20-07C, describing the proposed methodologies, the associated testing instrumentation, and the tailoring capabilities. The limitations of these methodologies and relative research, aiming to validate or improve them, are also presented highlighting potential deficiencies. This chapter aims to serve as a compact guide to EMC testing of space equipment according to the requirements of two of the most active organizations of space engineering.
Structural Features of Nominally Pure Lithium Niobate Crystals Grown from Boron-Doped Charge
Authors: Sidorov Nikolay , Titov Roman , Teplyakova Natalya A. , Palatnikov Mikhail , Syuy Alexander Vjacheslavovich
Published: November 2020

The features of the structure of single crystals LiNbO3:B3+ (0.12 and 0.18 wt %) grown by the Czochralski method from the mixture of different genesis were studied. It was found that boron is able to incorporate into the crystal structure of lithium niobate in a trace amounts (~ 10–4–10–5 wt %), decreasing the concentration of structural defects NbLi. Thus, ordering of structural units of the cation sublattice of lithium niobate crystals grown from a congruent composition melt approach in that of stoichiometric crystals.
Coaxial Aperture Arrays Produced by Ultrafast Direct Femtosecond Laser Processing with Spatially Multiplexed Cylindrical Vector Beams
Authors: Pavlov Dmitrii V. , Porfirev Aleksey P. , Dyshliuk Anton , Kuchmizhak Aleksandr A.
Published: November 2020

Direct femtosecond laser printing was used to fabricate circular-and coaxial-shaped hole arrays at ultrafast printing rate up to 106 elements per second. To achieve such fast printing rate, we implemented a spatial multiplexing of either a single Gaussian or cylindrical vector beams into linear array of identical laser spots. Being compared to ordinary microholes, the coaxial openings arranged at the same periodicity demonstrate enhanced transmission in the mid-IR spectral range resulted from coupling between localized electromagnetic mode supported by coaxial unit cell and the lattice-type surface plasmon resonance. At optimized geometry of the coaxial openings and their arrangement we demonstrated resonant transmission as high as 92% at wavelengths ranging from 7.5 to 9 μm. This makes the coaxial microhole arrays with tailored spectral properties produced with ultrafast and inexpensive direct laser printing promising for sensing applications based on surface enhanced infrared absorption.
Transformation of the Nanoporous Structure of Anodic Aluminium Oxide and its “Nonelectrolysis” Electroluminescence
Authors: Ovechenko Dmitry , Boychenko Alexander
Published: November 2020

On a film of aluminum oxide (Al2O3) formed by electrolytic oxidation in distilled water (DW), the growth, transformation of its nanoporous structure, and the generation of electroluminescence (EL) in ketones and related compounds containing carbonyl groups were studied. For those contributing to the brightest EL – acetylacetone and methylpyrrolidone, it was found that the processes described in these electrolytes proceed with the highest intensity. Under the same electrolytes and conditions, similar processes, but with a lower intensity, proceed for A2O3 formed on pure aluminum. It was found that, with the external voltage, thermodynamic and geometrical parameters of the electrolytic system being constant, the brightness characteristics of the EL of the anodic Al2O3 are influenced by its structural organization and the electrophysical characteristics of the electrolyte surrounding the oxide film, which is proposed to be arbitrarily called “nonelectrolysis” because electrolysis products are not revealed in it.
Monte Carlo Simulation of Magnetic Skyrmions in Ferromagnetic Films
Authors: Perzhu Alexander , Vasiliev Egor , Kapitan Dmitrii , Volotovskiy Roman , Rybin Alexey , Soldatov Konstantin , Makarov Alexander , Strongin Vladislav , Korol Alena , Shevchenko Yuriy , Nefedev Konstantin , Nefedev Konstantin , Kapitan Vitalii
Published: November 2020

Magnetic films, in which magnetic vortex textures - skyrmions appear because of competition between the direct Heisenberg exchange and the Dzyaloshinskii-Moriya interaction, were studied using the Monte-Carlo simulation technique. The conditions for the nucleation and stable existence of magnetic skyrmions in magnetic films in the frame of the classical Heisenberg model were considered in the paper. The process of nucleation of skyrmions with increasing of the external magnetic field was studied, various phases into which the Heisenberg spin system passes were recognized. A phase diagram was plotted: it shows the behavior of the system at the constant value of temperature depending on values of an external magnetic field and Dzyaloshinskii-Moriya interaction.
Monte Carlo Simulations of the Fast Remagnetization Process in Fept Granular Films
Authors: Shevchenko Yuriy , Volotovskiy Roman , Vasiliev Egor , Perzhu Alexander , Kapitan Dmitrii , Rybin Alexey , Soldatov Konstantin , Makarov Alexander , Strongin Vladislav , Medvedeva Alena , Kapitan Vitalii , Nefedev Konstantin
Published: November 2020

We utilize the Metropolis algorithm to obtain statistical averages of the domain wall length in a FePt granular structure after remagnetization is performed by an ultrashort polarized laser impulse. We propose and check the cluster-size-based order parameter, which along with magnetization, shows the domain wall length, and as a consequence, the average cluster size in the system. We treat the inverse Faraday effect as an external directed magnetic field and show impulse time- and laser power- dependent estimates within the Heisenberg model.
Heat Treatment of Nanostructured Powders Obtained by Spark Erosion of WC-8Co Cemented Carbide in Oil
Authors: Dvornik M.I. , Mikhailenko Elena A.
Published: November 2020

Spark erosion of WC-8Co carbide pieces in oil resulted in a powder consisting of nanostructured spherical microparticles formed by rapid crystallization of the melt. These particles consist of rounded WC grains with an average diameter of about 0.18 μm, surrounded by cobalt. The process productivity, specific energy consumption, microstructure, particle size distribution, chemical and phase compositions of the obtained powder are determined. It was found that as a result of oil pyrolysis, free carbon is formed (3.4 %), which makes this powder unsuitable for the production of carbide products from it. A technique has been developed and the process of controlled removal of excess carbon by annealing the obtained powder in a CO2 atmosphere at a temperature of 1000 °C has been studied. As a result of annealing for 120 minutes, the carbon content decreases to the required value (5.6 %). Studies of the phase composition and microstructure showed that the obtained particles consist of elongated WC grains, the average diameter of which increased to 0.43 μm.
Correlation between the Properties of PEO-Layer and Coating Formation Current Density
Authors: Suchkov Sergey N. , Gerasimenko Mariia S. , Nadaraia Konstantine V. , Imshinetsky Igor M. , Mashtalyar Dmitry V. , Minaev Alexander N. , Sinebryukhov Sergey L. , Gnedenkov Sergey V.
Published: November 2020

Presented paper considers the formation of protective coatings on MA8 magnesium alloy by plasma-electrolytic oxidation (PEO). The influence of current densities formation on the structure, corrosion properties of PEO-coatings was studied. Electrochemical and scanning electron microscopy of the surface and cross-section of the samples were carried out. The effect of changing the formation current density on the functional parameters of coatings, such as corrosion resistance, thickness and porosity was investigated.
The Influence of Temperature on the Lateral Photovoltaic Effect in the Fe3O4/SiO2/n-Si Structure
Authors: Pisarenko Tatiana A. , Korobtsov Vladimir V. , Balashev Vyacheslav V. , Dimitriev Artem A.
Published: November 2020

We report on the results of a study of the lateral photovoltaic effect in the Fe3O4/SiO2/n-Si(001) structure at temperatures of 300 and 122 K under continuous and pulsed illumination. It is found that when the temperature changes from 300 to 122 K, the LPE sensitivity decreases from 112 to 65 mV/mm. At pulsed illumination, an increase of rise time and a fall time is observed with decreasing temperature. From a consideration of the energy band diagrams and equivalent circuits of the Fe3O4/SiO2/n-Si structure, it is assumed that the detected temperature effects of LPE are due to the strong dependence of the magnetite film resistance on temperature.
NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor
Authors: Sun Boyue , Zeng Haoyang , Liang Jiaqian , Zhang Lele , Hu Haiyang , Wang Quanyi , Meng Wei , Li Chenhui , Ye Fuqiang , Wang Chen , Zhu Juanjuan
Published: November 2020

The RIG-I receptor induces the innate antiviral responses upon sensing RNA viruses. The mechanisms through which RIG-I optimizes the strength of the downstream signaling remain incompletely understood. In this study, we identified that NSUN5 could potentiate the RIG-I innate signaling pathway. Deficiency of NSUN5 enhanced RNA virus proliferation and inhibited the induction of the downstream antiviral genes. Consistently, NSUN5-deficient mice were more susceptible to RNA virus infection than their wild-type littermates. Mechanistically, NSUN5 bound directly to both viral RNA and RIG-I, synergizing the recognition of dsRNA by RIG-I. Collectively, to our knowledge, this study characterized NSUN5 as a novel RIG-I coreceptor, playing a vital role in restricting RNA virus infection.
LncRNA GClnc1 may contribute to the progression of ovarian cancer by regulating p53 signaling pathway
Authors: Li Hu , Zeng Zheng , Yang Xiang , Chen Ye , He Lei , Wan Ting
Published: November 2020

Ovarian cancer (OC) is one of the most prevalent and deadly types of gynecological malignancy. Since current treatments are not effective against OC, it is imperative to develop novel potential therapeutic targets for managing OC. In this study, we aimed to uncover the underlying molecular mechanism of long non-coding RNA (lncRNA) GClnc1 related to p53 signaling pathway in OC. The expression of lncRNA H19 GClnc1 was markedly higher in OC samples than the related normal tissues. Next, we found that lncRNA GClnc1 inhibited p53. In addition, the lncRNA GClnc1 overexpression promoted the cell proliferation and migration in vitro. Subsequently, p53 silencing obligated the effect of lncRNA GCln1 knock down on cell proliferation and migration. To sum up, LncRNA GClnc1 contributes to the progression of OC by regulating p53 signaling pathway. Meanwhile, our findings also suggested that lncRNA GClnc1 may serve as a novel therapeutic target for OC patients.
Odonata assemblages in anthropogenically impacted lotic habitats
Authors: Vilenica Marina , Kerovec Mladen , Pozojević Ivana , Mihaljević Zlatko
Published: November 2020

Increasing human pressures have a negative impact on freshwater habitats and their biota worldwide. To protect habitats and the species contained within them, ecological assessments over a gradient of near natural to degraded freshwater habitats are essential. Odonata assemblages were investigated at 46 study sites in Croatia encompassing slightly to heavily modified lowland rivers and streams. Nymphs were sampled between April and September 2016 using a benthos hand net. A total of 19 species was recorded, and Ischnura elegans (Vander Linden, 1820) and Platycnemis pennipes (Pallas, 1771) were most frequently recorded. RDA analysis indicated that water pollution (i.e. levels of chemical oxygen demand and total organic carbon), water temperature and oxygen concentration had the highest influence in the formation of Odonata assemblages at a specific habitat, reflecting their widely recognized bioindicator properties. This study showed that degraded lowland rivers can provide habitat for a relatively low number of species with broad ecological tolerance, while rare and specialist species are generally not able to reproduce there. These results contribute to our knowledge of Odonata occurrence in anthropogenically impacted habitats, and their relationships with such degraded environment.
Il dibattito in bioetica - I lavori della Commissione ministeriale per lo studio della utilizzazione delle cellule staminali
Authors: Bompiani A.
Published: November 2020

Non disponibile.
Il Medico Attore e l’Attore Medico
Authors: De Caprio Lorenzo , Cinque Paola
Published: November 2020

Il testo illustra i “difficili” rapporti, i grotteschi rimandi e le sotterranee intese tra teatro e medicina. Da un lato gli autori fanno emergere, anche paradossalmente, i caratteri “teatrali” della professione, dall’altro sottolineano il fatto che la maschera del medico nel Teatro abbia assolto costantemente una funzione di critica sociale richiamando costantemente, severamente, energicamente i professionisti della vita al rispetto dei valori, umani prima e morali poi, che contraddistinguono una professione che ha al centro dei suoi interessi l’uomo. Nello stesso tempo l’attore che si fa medico sulla scena permette di seguire con sorprendente fedeltà la nascita, l’evoluzione e l’ascesa del ruolo medico nelle società occidentali. Scena invariante dell’azione del medico si rivela la sofferenza umana e sua contro-parte la Morte, così, tra le polarità del medico che si fa attore, e dell’attore che si fa medico emerge un percorso storico che dal Tragico greco, giunge all’Umano cristiano, e poi passando per il Comico, ci porta al Dis-Umano contemporaneo.
Evoluzione storica delle “Carte dei diritti dei morenti”
Authors: Pennacchini M. , Sacchini D. , Spagnolo A.G.
Published: November 2020

L’intento perseguito dagli autori con questo lavoro è stato quello di ripercorrere l’evoluzione negli ultimi decenni delle “carte” in cui vengono indicati i diritti delle persone morenti. Una storia che si va a contrapporre, con una sorprendente coincidenza nella cronologia, ai successivi momenti della depenalizzazione, prima, e della legalizzazione, poi, dell’eutanasia. Tali “carte”, infatti, hanno sostanzialmente inteso contrapporre il right to death with dignity al right to death senza altre specificazioni, rivendicato dai movimenti e dalle società a favore dell’eutanasia volontaria e del suicidio assistito.

Questo lavoro, quindi, trova il suo momento iniziale con l’identificazione e l’analisi delle motivazioni socio-culturali oltre che di quelle più propriamente scientifiche che hanno portato all’elaborazione della prima carta dei diritti del morente, capostipite in un certo senso di tutte quelle seguenti. Dopo di che mostra l’evoluzione peculiare che tali carte, c.d. di prima generazione hanno avuto in Europa, e da ultimo illustra come esse si sono evolute, sia in Europa sia negli Usa in anni più recenti.

Da ultimo, a conclusione della “review” storica, gli autori hanno voluto presentare la Carta dei diritti del malato cronico in evoluzione di malattia elaborata nel 1999 all’interno del Policlinico Universitario “Agostino Gemelli” dell’Università Cattolica, esaminandone il contenuto e le ragioni che hanno portato alla sua elaborazione.
Medicina ufficiale e terapie non convenzionali: dal conflitto all’integrazione?
Authors: Bellavite P. , Semizzi M. , Musso P. , Ortolani R. , Andrioli G.
Published: November 2020

La distinzione tra medicina ufficiale e medicine alternative (più propriamente denominate non-convenzionali o complementari) va inquadrata sul piano storico ed epistemologico, come parte di un continuo e mai concluso confronto tra diversi paradigmi scientifici e medici. Il ricorso a pratiche mediche di origine orientale o comunque di matrice extra-scientifica è in espansione in tutti i Paesi europei e negli Stati Uniti e ciò pone un’ampia serie di problemi sociosanitari, deontologici, etici, metodologici. La crisi attuale della medicina occidentale deriva sostanzialmente dalla difficoltà di conciliare il progressivo dominio dell’approccio scientifico-molecolare e tecnologico con la crescente necessità di riscoprire gli aspetti più personali ed individualizzati della cura, che sono particolarmente importanti nelle malattie croniche e multifattoriali. Le medicine non convenzionali possono probabilmente contribuire a colmare alcune lacune metodologiche e concettuali lasciate dalla super-specializzazione e dal prevalere del pensiero razionalista rispetto a quello empirico negli ultimi secoli e particolarmente negli ultimi decenni. Il modo più corretto di guardare al fenomeno è quello di esaminarne le ragioni d’essere, individuarne le molte possibili distorsioni, sfruttarne le potenziali positività in vista di una possibile integrazione di diversi approcci terapeutici. Tale eventuale integrazione di alcune pratiche non convenzionali richiede un maggiore impegno nella ricerca scientifica e nella qualifica delle varie figure professionali.
Il Neonato da Gravidanza Gemellare Spontanea e Indotta
Authors: Zuppa A. A. , De Luca D. , Scapillati M. E.
Published: November 2020

Gli Autori riportano il dato epidemiologico dell’aumentata incidenza di gemellarità verificatosi dell’ultimo decennio a causa soprattutto della diffusione delle tecniche di induzione della gravidanza (farmacologica e da tecniche di fecondazione artificiale - GIFT e FIVET). Gli Autori si soffermano sugli aspetti clinico-assistenziali delle gravidanze gemellari soprattutto sul versante neonatale. Vengono inoltre presi in considerazione alcuni aspetti etici relativi all’induzione di gravidanza: rilevanza dei rischi in rapporto ai benefici, soprattutto relativamente alla maggiore mortalità e morbilità perinatale legata, non solo all’aumentata incidenza di gemellarità. Ma all’induzione stessa della gravidanza; l’induzione della gravidanza intesa non come procedura terapeutica ma come intervento “sostitutivo”- il sopravvento della cosiddetta medicina dei desideri.
Long-Term Glycaemic Durability of Early Combination Therapy Strategy versus Metformin Monotherapy in Korean Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Authors: Yoo Soon-Jib , Chang Sang-Ah , Sohn Tae Seo , Kwon Hyuk-Sang , Lee Jong Min , Moon Sungdae , Proot Pieter , Paldánius Päivi M , Yoon Kun Ho
Published: November 2020

We assessed the glycaemic durability with early combination (EC; vildagliptin+metformin [MET], n=22) versus MET monotherapy (n=17), among newly-diagnosed type 2 diabetes mellitus (T2DM) enrolled (between 2012 and 2014) in the VERIFY study from Korea (n=39). Primary endpoint was time to initial treatment failure (TF) (glycosylated hemoglobin [HbA1c] ≥7.0% at two consecutive scheduled visits after randomization [end of period 1]). Time to second TF was assessed when both groups were receiving and failing on the combination (end of period 2). With EC the risk of initial TF significantly reduced by 78% compared to MET (n=3 [15%] vs. n=10 [58.7%], P=0.0228). No secondary TF occurred in EC group versus five patients (29.4%) in MET. Patients receiving EC treatment achieved consistently lower HbA1c levels. Both treatment approaches were well tolerated with no hypoglycaemic events. In Korean patients with newly diagnosed T2DM, EC treatment significantly and consistently improved the long-term glycaemic durability as compared with MET.
PGS1, a new low cost and low power Portable Geo-physical Station “All in One”. Design and test
Authors: Costanza Antonio , Fertitta Gioacchino , Yang William , D'Anna Giuseppe , Chiarabba Claudio
Published: November 2020

PGS1 is a new compact portable seismic station, designed at INGV OBS and Earth Lab, that is specifically intended for the deployment of dense arrays of seismographs on-shore. With its low cost, compact design, high data-quality and long battery life, PGS1 is a perfect solution for seismic monitoring networks. PGS1 design is based on a solid polypropylene suitcase, containing a complete data acquisition system, two battery packs and a photovoltaic panel. The new Earth Lab 5s medium-period seismic sensor is included. The whole system meets the IP67 standard requirements both in transport and in acquisition configuration. PGS1 is normally equipped with one battery pack, one more pack can be added inside the suitcase achieving 40 days of battery life. The station is equipped with a photovoltaic panel, useful to extend the deployment length. Inside the suitcase, there are compartments where to store the seismic sensor, the photovoltaic panel and all the cables. Therefore, the station is very easy to transport.
VRIJEDNOSNO-KREATIVNE MOGUĆNOSTI OBRAZOVNE INKLUZIJE / VALUES AND CREATIVITY OPPORTUNITIES OF INCLUSIVE EDUCATION
Authors: Manko Anida
Published: November 2020

Inclusion should be an important value of every society. Education institutions are the place for developing universal values that should enable every individual to express their needs in a unique and different way, which will prompt an inclusive environment that values diversity. Forming an inclusive environment fosters opportunity for developing creativity. Although inclusive education and creativity are rarely perceived as related, this paper aims to present the values and creativity opportunities of inclusive education. A chorus of criticism directed at the education system shows that creativity is not recognized enough, especially when it comes to students with disabilities whose creativity is often not seen as one of their abilities, even when it is developed. That happens as a result of perceiving the students through the prism of their disability. The emphasis should be on developing the values during the preschool period, which is the most significant period of a child’s development as that is the time when the foundations of the personality development are set. The subject of this research is focused on identifying the values and creativity opportunities of inclusive education, while the intention is to recognize the possible ways of developing creativity in an inclusive environment. The aim of the research was to examine the educators’ opinions on values and creativity opportunities of inclusion. As of recently, preschool institutions have been now facing an increasing number of children with disabilities enrolling in. Therefore, new challenges are posed on the preschool education when it comes to providing the children with the conditions for a development that meets their needs and abilities. The purpose of the paper is to offer strategies that will ensure the development of core values while respecting the creative potential of each child in an inclusive environment.
IN MEMORIAM
Authors: Ibrišimović-Šabić Adijata
Published: November 2020

In Memoriam.
Editorial & Review Process
Authors: Journals EJMS
Published: November 2020

Editorial & Review Process
Adesão ao tratamento com antineoplásicos orais em pacientes com câncer de mama
Authors: Ribeiro Teixeira Alinne , Moreira Ruiz Bianca , Ramalho Cardoso Nathalia , De Franco Rennó Verônica
Published: November 2020

Objetivos: avaliar fatores associados à adesão ao tratamento com fármacos de ação antineoplásica por via oral em pacientes com câncer de mama. Métodos: foi realizado levantamento bibliográfico do período de 2002 a 2018 nas bases de dados Scielo, Pubmed e Lilacs. Foram selecionados 50, após leitura dos resumos, foram selecionados  30 estudos para leitura completa. Com isso, foram excluídos os que se referem ao acompanhamento farmacoterapêutico de outras doenças não compatíveis com o tema. Dos estudos avaliados, 22 abordavam o tema do estudo e foram utilizados como referência. Conclusão: a adesão ao tratamento com antineoplásicos orais para o tratamento de câncer de mama ainda é um desafio para saúde pública e, em especial para os farmacêuticos que atuam na dispensação dos referidos medicamentos. Com o estudo, foi possível observar que existem múltiplas variáveis que interferem na adesão ao tratamento, sendo que muitos dos fatores envolvidos, estão ligados à elementos intrínsecos da paciente. Entretanto, quando se analisam os fatores extrínsecos, percebe-se que a atuação do farmacêutico no momento da dispensação possui grande influência no sucesso do tratamento, uma vez que é notável que a correta e adequada orientação quanto ao tratamento proposto é um fator fundamental para aumentar a adesão ao tratamento por mulheres com câncer de mama. Com isso, pode-se inferir que se faz necessária a educação continuada de profissionais da saúde que atuam nesta etapa tão importante do tratamento das pacientes.
Estudo comparativo de custo-efetividade de técnicas farmacológicas para prevenção de náuseas e vômitos pós-operatórios em gastroplastias
Authors: Pereira da Silva Bruna , Pellegrini Gustavo Batista , Vasco Pereira Gustavo José
Published: November 2020

Introdução: As náuseas e vômitos são um dos maiores problemas em pós-operatórios gerando custos não previstos que podem e devem ser evitados. Com a introdução da farmacoeconomia, foi possível prever eventos adversos relacionados a cirurgias e, com isso, mitigar a probabilidade de impactos econômicos negativos relacionados a estes eventos. Objetivo: O objetivo deste estudo é avaliar as mais diversas técnicas farmacológicas de prevenção de náuseas e vômitos pós-operatórios em gastroplastias, baseando-se em estudos de custo-efetividade que levem em conta variáveis como diminuição do tempo e valor da internação perioperatória e da probabilidade de eventos adversos relacionados à cirurgia. Todas as classes mais utilizadas foram avaliadas. Metodologia:  Foi conduzido um estudo econômico de custo-efetividade, tendo como outcomes mitigar qualquer probabilidade de evento adverso relacionado ao pós-operatório de gastroplastia. Para a questão econômico, as bases BPS e CMED foram utilizadas e as bases de pesquisa Scielo, Schoolar Google e PubMed para os demais assuntos. Resultados: A associação mais custo-efetiva e custo-benefício foi dexametasona + ondansetrona, podendo ser estendida para mais uma classe medicamentosa dependendo da pontuação no escore de Apfel. Conclusão: Conclui-se que as recomendações são ferramentas valiosas para o anestesista, fundadas em evidências sólidas ao longo dos anos, que beneficia o profissional, a instituição e o paciente em questão.