bluuebunny/crossref_metadata_2025 huggingface dataset:
A MULTICENTER REVIEW EVALUATING THE RISK OF RHEGMATOGENOUS RETINAL DETACHMENT POST ENDOPHTHALMITIS
Authors: Nanji Keean , Kherani Imaan , Khan Mohammad , Williams Geoff , Muni Rajeev H. , Chaudhary Varun , Kherani Amin
Published: April 2022

Purpose:

To describe the characteristics of rhegmatogenous retinal detachments (RDs) that developed after endophthalmitis and to provide insight regarding incidence, management, and outcomes.

Methods:

Retrospective chart review of consecutive patients diagnosed with endophthalmitis at two Canadian institutions and from one surgeon at a third center over a 10-year period.

Results:

Three hundred sixteen eyes presented with endophthalmitis of which 32 (10%) were complicated by subsequent RD. The mean age (SD) of patients was 72.0 (13.77) years. Intravitreal injections (33%) and cataract surgery (31%) were the most common inciting events for the endophthalmitis. Cases were managed with tap and inject (16%), vitrectomy (30%), or both (47%). There were no differences in the rate of RD when comparing the inciting events, microbial growth, or management approaches. Baseline visual acuity was the only predictor of RD (P = 0.009). There was an improvement in visual acuity following management of the RD (logarithm of the minimum angle of resolution 2.33 vs. 1.69 or Snellen hand motion vs. 20/980, P = 0.009), but final visual acuity in these patients was worse than in those who did not develop RD (logarithm of the minimum angle of resolution 1.69 vs. 1.27 or Snellen 20/980 vs. 20/372, P = 0.029).

Conclusion:

All patients with RD post endophthalmitis required additional surgery, and functional outcomes remained poor. Nevertheless, repair of these RDs can preserve some vision and be globe saving.
Pasteurella multocida Bacterial Meningitis in a 33-Day-Old Infant
Authors: Slehria Trisha , Hendricks Sydney , Honeycutt Travis
Published: April 2022

A 33-day-old previously healthy term female is admitted to the pediatric intensive care unit with fever, lethargy and bulging fontanel. Given concern for meningitis, a lumbar puncture is performed and empiric treatment is initiated. The cerebrospinal fluid culture results reveal Pasteurella multocida. The patient is treated with intravenous ampicillin for 3 weeks and discharged with close outpatient follow-up.
Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists
Authors: Cheung Veronica K.Y. , Hulme Katherine , Schifter Mark , Palme Carsten , Low Tsu-Hui (Hubert) , Clark Jonathan , Gupta Ruta
Published: April 2022

Oral epithelial dysplasia (OED) represents a spectrum of histologic changes in the oral cavity mucosa that has the potential to transform into oral squamous cell carcinoma. Predicting the risk of malignant transformation is predominantly based on clinicopathologic correlation, histologic examination and grading. OED often poses a diagnostic challenge, primarily due to its histologic mimics and a large number of terminologies used in the literature. The grading system for OED is also fraught with significant interobserver variability. This review summarizes the essential clinical and histopathologic features of OED and its mimics. Practical preanalytical, analytical, and postanalytical considerations for anatomic pathologists are discussed to improve the diagnostic accuracy and increase the reproducibility in the grading of OED.
Risk Factors for Sepsis-Associated Acute Kidney Injury in the PICU: A Retrospective Cohort Study
Authors: Ninmer Emily K. , Charlton Jennifer R. , Spaeder Michael C.
Published: April 2022

OBJECTIVES:

Acute kidney injury (AKI), particularly of greater severity and longer duration, is associated with increased morbidity and mortality in the pediatric population. AKI frequently occurs during sepsis, yet the knowledge of risk factors for sepsis-associated AKI in the PICU is limited. We aimed to identify risk factors for AKI that develops or persists after 72 hours from sepsis recognition in pediatric patients with severe sepsis.

DESIGN:

Retrospective cohort study.

SETTING:

PICU at an academic, tertiary-care center.

PATIENTS:

Children greater than 1 month and less than or equal to 18 years with severe sepsis in the combined cardiac and medical/surgical PICU between December 1, 2013, and December 31, 2020, at the University of Virginia Children’s Hospital.

INTERVENTIONS:

None.

MEASUREMENTS AND MAIN RESULTS:

The cohort included 124 patients with severe sepsis with 33 patients (27%) who were postcardiac surgery with cardiopulmonary bypass. AKI was defined by the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. The primary outcome was severe AKI, defined as KDIGO stage 2 or 3 AKI present at any point between days 3 and 7 after sepsis recognition. Severe AKI was present in 25 patients (20%). Factors independently associated with severe AKI were maximum vasoactive-inotropic score (VIS) within 48 hours after sepsis recognition and fluid overload. The presence of severe AKI was associated with increased inhospital mortality.

CONCLUSIONS:

In children with severe sepsis, the degree of hemodynamic support as measured by the VIS and the presence of fluid overload may identify patients at increased risk of developing severe AKI.
Pediatric Emergency Medicine Physicians' Perspectives on Emergency Care of Children With Medical Complexity
Authors: Pulcini Christian D. , Dubuque Amy , Lamberson Miles , Macy Michelle L. , Mistry Rakesh D. , Pruitt Christopher M. , Schnadower David , Zorc Joseph J. , Stevens Martha W.
Published: April 2022

Objective

Children with medical complexity (CMC) compose 1% of the pediatric population but account for 20% of pediatric emergency department (ED) visits. Previous descriptions of challenges and interventions to ensure quality of care are limited. Our objective was to elicit pediatric emergency medicine (PEM) physicians' perspectives on challenges and opportunities for improvement of emergency care of CMC, with a focus on emergency information forms (EIFs).

Methods

We conducted a web-based survey of PEM physicians participating the American Academy of Pediatrics Section on Emergency Medicine Survey listserv. The survey was designed using an expert panel, and subsequently piloted and revised to an 18-item survey. Data were analyzed with descriptive statistics.

Results

One hundred fifty-one of 495 respondents (30%) completed the survey. Most respondents (62.9%) reported caring for >10 CMC per month. Whereas overall medical fragility and time constraints were major contributors to the challenges of caring for CMC in the ED, communication with known providers and shared care plans were identified as particularly helpful. Most respondents did not report routine use of EIFs. Anticipated emergencies/action plan was deemed the most important component of EIFs.

Conclusions

Most PEM physicians view the care for CMC in the ED as challenging despite practicing in high-resource environments. Further research is needed to develop and implement strategies to improve care of CMC in the ED. Understanding experiences of providers in general ED settings is also an important next step given that 80% of CMC present for emergency care outside of major children's hospitals.
A Multistate Survey of Pediatric Emergency Care Coordinator Activities
Authors: Samuels-Kalow Margaret E. , Boggs Krislyn M. , Alpern Elizabeth R. , Camargo Carlos A.
Published: April 2022

Background

Pediatric emergency care coordinators (PECCs) are associated with pediatric readiness of emergency departments (EDs). National organizations have called for PECCs in all EDs. Although the National Pediatric Readiness Program provides a list of suggested tasks for each PECC, little is known about implementation. Our objective was to describe the role of PECCs in EDs.

Methods

We analyzed data from the 2019 National ED Inventory—USA to identify EDs with PECCs in 8 states (Arkansas, Florida, Iowa, Maryland, Nebraska, New York, Vermont, and Wisconsin). We called each ED that reported having a PECC to administer a standardized survey assessing NRPP tasks, specifically quality improvement (QI), education provision, skill verification, equipment responsibilities, and how many hours the PECC devoted to the role.

Results

Of the 201 of 830 EDs (24%) that reported a PECC, 167 (83%) completed the survey, with >80% response rate in each state. Of these, 153 EDs (92%) confirmed a PECC, and during the past year, 81% participated in QI initiatives, 93% provided pediatric education, 90% verified staff skills, and 90% were responsible for ensuring medications, equipment, supplies, and resources for children. The median number of hours per week that PECCs devoted to this role was 12 (interquartile range, 5–40). There was wide variation between states (eg, 50% of PECCs in Vermont participating in QI activities, as compared with 100% in Nebraska).

Conclusions

Most PECCs report participating in the suggested National Pediatric Readiness Program tasks, although there was variation by state. Future directions for this work include assessing the association between PECC tasks and patient outcomes.
Sledding Accidents at a Level 1 Pediatric Trauma Center Between 2006 and 2016
Authors: Ryan Sydney , Fenton Stephen J. , Hansen Kris , Hewes Hilary A.
Published: April 2022

Background

Sledding is not a risk-free winter sport. According to the US Consumer Product Safety Commission, there were an estimated 13,954 sledding accidents requiring medical care in 2010. However, specific information concerning pediatric injuries related to sledding is not well defined.

Objectives

This study aimed to identify the most common types of injuries associated with sledding accidents and demographic factors related to risk of injury in pediatric patients, and to compare injuries associated with 2 different age groups and sexes.

Methods

This is a retrospective descriptive study of pediatric patients (<18 years of age) presenting to a regional level I pediatric trauma center secondary to a sledding injury between 2006 and 2016. Demographic information including sex, age, mechanism of injury, and injury severity score was captured and analyzed using descriptive statistics.

Results

There were 209 patients identified for 10 years. There were no mortalities. There were 85 patients with primary head injury, of which 82 (96.5%) were hospitalized and 33 (38.8%) required an intensive care unit (ICU) stay. Seventy-five patients primarily suffered from extremity injuries, of which 56 (74.6%) had lower extremity fractures requiring operative intervention. There was no difference in ICU or length of stay between younger children (0–11 years) and adolescents (12–18 years) or between male and female patients.

Conclusions

Childhood sledding can result in a variety of significant injuries requiring surgical intervention and hospitalization. Children pulled on sleds behind motorized vehicles are at higher risk for more severe injuries resulting in a higher rate of ICU admission.
Value of Temperature for Predicting Invasive Bacterial Infection in Febrile Infants
Authors: de la Torre Mercedes , Gómez Borja , Velasco Roberto ,   on behalf of the Group for Study of Febrile Infant of Spanish Pediatric Emergency Research Group (RISeuP-SPERG)
Published: April 2022

Objective

This study aimed to analyze the prevalence of invasive bacterial infection (IBI) among infants younger than 90 days with fever without source according to the degree of fever.

Methods

We performed a secondary analysis of a multicenter study with 19 participating Spanish pediatric emergency departments that included 3401 febrile infants 90 days or younger.

Results

Prevalence of IBI was 3.2% (5.3% among infants <29 days old, 2.5% among those 29–60 days old, and 2.2% among those 61–90 days old). Prevalence of bacteremia increased with the degree of fever, meanwhile the prevalence of bacterial meningitis did not. No cutoff point was useful for ruling out an IBI safely. Overall, 46.7% of the IBIs were diagnosed in patients with temperature <38.6° (sensitivity, 53.3%; negative likelihood ratio, 0.81).

Conclusions

Performing blood tests should be recommended in infants 90 days or younger with temperature ≥38°C without source regardless of the degree of fever.
Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: a retrospective cohort study
Authors: Hebert Anne , Simons Annet , Schuurs-Hoeijmakers Janneke H.M. , Koenen Hans J.P.M. , Zonneveld-Huijssoon Evelien , Henriet Stefanie S.V. , Schatorjé Ellen J.H. , Hoppenreijs Esther P.A.H. , Leenders Erika K.S.M. , Janssen Etienne J.M. , Santen Gijs W.E. , de Munnik Sonja A. , van Reijmersdal Simon V. , van Rijssen Esther , Kersten Simone , Netea Mihai G. , Smeets Ruben L. , van de Veerdonk Frank L. , Hoischen Alexander , van der Made Caspar I.
Published: April 2022

Background

De novo variants (DNVs) are currently not routinely evaluated as part of diagnostic whole exome sequencing (WES) analysis in patients with suspected inborn errors of immunity (IEI).

Methods

This study explored the potential added value of systematic assessment of DNVs in a retrospective cohort of 123 patients with a suspected sporadic IEI who underwent patient-parent trio-based WES.

Results

A likely molecular diagnosis for (part) of the immunological phenotype was achieved in 12 patients with the diagnostic in silico IEI WES gene panel. Exome-wide evaluation of rare, non-synonymous DNVs affecting coding or splice site regions led to the identification of 14 candidate DNVs in genes with an annotated immune function. DNVs were identified in IEI genes (NLRP3 and RELA) and potentially novel candidate genes, including PSMB10, DDX1, KMT2C and FBXW11. The FBXW11 canonical splice site DNV, in a patient with autoinflammatory disease, was shown to lead to defective RNA splicing, increased NF-κB p65 signalling, and elevated IL-1β production in primary immune cells.

Conclusions

This retrospective cohort study advocates the implementation of trio-based sequencing in routine diagnostics of patients with sporadic IEI. Furthermore, we have provided functional evidence supporting a causal role for FBXW11 loss-of-function mutations in autoinflammatory disease.

Funding

This research was supported by grants from the European Union, ZonMW and the Radboud Institute for Molecular Life Sciences.
Safety and feasibility of an FES-Cycling based neuromuscular evaluation method in mechanically ventilated patients
Authors: Figueiredo Thainá de Gomes , Frazão Murillo , Werlang Luís Augusto , Azevedo Cássio , Kunz Adelar , Peltz Maikel , Câmara Furtado Veridiana , de Souza Edgar Brito , de Moura Júlio Francisco , Silva Rosane Maria , Sobral Filho Dário Celestino
Published: April 2022

Purpose

FES-Cycling can be used to assess neuromuscular performance, however the safety and feasibility of this evaluation method has never been investigated.

Materials and methods

an observational prospective study was carried out. The FES-Cycling equipment was set in the evaluation mode. For safety determination, hemodynamic parameters and peripheral oxygen saturation were measured before and immediately after the evaluation protocol, as well as venous oxygen saturation and blood lactate. The creatine phosphokinase level (CPK) was measured before and 24, 48 and 72 hours after the test. The time spent to carry out the entire evaluation protocol and the number of patients with visible muscle contraction were recorded to assess feasibility.

Results

Heart rate, systolic and diastolic blood pressure did not change after protocol evaluation, as well as peripheral and venous oxygen saturation (p > 0.05). Moreover, blood lactate did not change (p > 0.05). CPK did not change up to 72 hours after the test (p > 0.05). The time for evaluation was 11.3 (SD = 1.1) minutes. Furthermore, 75% of the patients presented very visible muscle contraction, 25% of the patients presented barely visible and no patients presented non-visible muscle contraction.

Conclusions

FES-Cycling based neuromuscular evaluation method is safe and feasible.
Triangulating Causality Between Childhood Obesity and Neurobehavior: Twin and Longitudinal Evidence
Authors: Kulisch Leonard Konstantin , Arumäe Kadri , Briley D. A. , Vainik Uku
Published: April 2022

Objective

Childhood obesity is a serious health concern that is not yet fully understood. Previous research has linked obesity with neurobehavioral factors such as behavior, cognition, and brain morphology. The causal directions of these relationships remain mostly untested.

Methods

We filled this gap by using the Adolescent Brain Cognitive Development study cohort comprising 11,875 children aged 9–10. First, correlations between body mass percentile and neurobehavioral measures were cross-sectionally analyzed. Effects were then aggregated by neurobehavioral domain for causal analyses. Direction of Causation twin modeling was used to test the direction of each relationship. Findings were validated by longitudinal cross-lagged panel modeling.

Results

Body mass percentile correlated with measures of impulsivity, motivation, psychopathology, eating behavior, and cognitive tests (executive functioning, language, memory, perception, working memory). Higher obesity was also associated with reduced cortical thickness in areas of the frontal and temporal lobe but with increased thickness in parietal and occipital brain areas. Similar although weaker patterns emerged for cortical surface area and volume. Twin modeling suggested causal effects of childhood obesity on eating behavior (β=.26), cognition (β=.05), cortical thickness (β=.15), and cortical surface area (β=.07). Personality/psychopathology (β=.09) and eating behavior (β=.16) appeared to causally influence childhood obesity. Longitudinal evidence broadly supported these findings. Results regarding cortical volume were inconsistent.

Conclusions

Results supported causal effects of obesity on brain functioning and morphology, consistent with effects of obesity-related brain inflammation on cognition. The present study highlights the importance of physical health for brain development during childhood and may inform interventions aimed at preventing or reducing pediatric obesity.
Berberine Bridge Enzyme-Like Oligosaccharide Oxidases Act As Enzymatic Transducers Between Microbial Glycoside Hydrolases and Plant Peroxidases
Authors: Scortica Anna , Giovannoni Moira , Scafati Valentina , Angelucci Francesco , Cervone Felice , De Lorenzo Giulia , Benedetti Manuel , Mattei Benedetta
Published: April 2022

OG-oxidases (OGOXs) and CD-oxidase (CELLOX) are plant berberine bridge enzyme-like oligosaccharide oxidases that oxidize oligogalacturonides (OGs) and cellodextrins (CDs), cell wall fragments with nature of damage-associated molecular patterns (DAMPs). The oxidation of OGs and CDs attenuates their elicitor activity by concomitantly releasing H2O2. Here, we demonstrate that the H2O2 generated downstream of the combined action between a fungal polygalacturonase and OGOX1 or an endoglucanase and CELLOX can be directed by plant peroxidases (PODs) either towards a reaction possibly involved in plant defence such as the oxidation of monolignol or a reaction possibly involved in a developmental event such as the oxidation of auxin (IAA), pointing to OGOX1 and CELLOX as enzymatic transducers between microbial glycoside hydrolases and plant PODs.
Accelerated mass transfer from frozen thin films during thin-film freeze-drying
Authors: Wang Jie-Liang , Kuang Manlei , Xu Haiyue , Williams Robert O. , Cui Zhengrong
Published: April 2022

Freeze-drying, or lyophilization, is widely used to produce pharmaceutical solids from temperature-sensitive materials but the process is time and energy inefficient. Herein, using E. coli as a model live organism, whose viability in dry powders is highly sensitive to the water content in the powders, we demonstrated that the drying rate of thin-film freeze-drying (TFFD) is significantly higher than that of the conventional shelf freeze-drying, likely because the large total surface area from the loosely stacked frozen thin films and the low thickness of the thin-films enable faster and more efficient mass transfer during freeze-drying. The highly porous nature and high specific surface area of the thin-film freeze-dried powders may have contributed to the faster mass transfer as well. Moreover, we demonstrated that TFFD can be applied to produce dry powders of E. coli and L. acidophilus with minimum bacterial viability loss (i.e., within one log reduction), and the L. acidophilus dry powder is suitable for intranasal delivery. It is concluded that TFFD technology is promising in addressing the time-and cost-inefficient issue of conventional shelf freeze-drying.
Peptidergic signaling controls the dynamics of sickness behavior inCaenorhabditis elegans
Authors: Marquina-Solis Javier , Vandewyer Elke , Hawk Josh , Colón-Ramos Daniel A. , Beets Isabel , Bargmann Cornelia I.
Published: April 2022

Pathogenic infection elicits sickness behaviors that promote recovery and survival of the host. For example, following infection with the pathogenic bacteriumPseudomonas aeruginosaPA14, the nematodeCaenorhabditis elegansmodifies its sensory preferences to avoid the pathogen. Here we identify antagonistic neuromodulatory circuits that shape this sickness behavior. Using an unbiased cell-directed neuropeptide screen, we show that AVK neurons upregulate and release FMRFamide-like FLP-1 neuropeptides during infection to drive pathogen avoidance. Manipulations that increase or decrease AVK signaling accelerate or delay pathogen avoidance, respectively, implicating AVK in the dynamics of sickness behavior. FLP-1 neuropeptides act via the G-protein-coupled receptor DMSR-7 in RIM/RIC neurons to reduce tyraminergic/octopaminergic signaling that opposes pathogen avoidance. RIM/RIC neurons relay parallel signals from neuropeptides and the cytokine TGF-β that represent internal and external regulators of pathogen avoidance. Our results demonstrate that antagonism between neuromodulatory systems results in slow, graded transitions between alternative behavioral states.
Dual orexin antagonist DORA-22 suppressed posttraumatic seizures and enhances GABAergic inhibition in dentate granule cells
Authors: Konduru Sruthi R. , Isaacson Jesse R. , Zhou Zihao , Rao Rohan K. , Lasky Danny J. , Vattem Swati S. , Rewey Sophie J. , Jones Mathew V. , Maganti Rama K.
Published: April 2022

Background

Traumatic brain injury (TBI) can result in posttraumatic epilepsy (PTE) and sleep disturbances. We hypothesized that treatment with sleep aids after TBI can ameliorate PTE.

Methods

CD-1 mice underwent controlled cortical impact (CCI), sham craniotomy or no craniotomy. Sham and CCI groups underwent a month-long treatment with sleep aids including a dual orexin antagonist (DORA-22) or THIP (gaboxadol). We performed week-long EEG recordings during week-1 of treatment and again at months 1, 2 and 3. Seizure analysis occurred at all-time points and sleep analysis occurred in week-1 and month-1 recordings in all groups. Subsets of animals in sleep aid-treated and untreated CCI, and sham groups were subjected to voltage clamp experiments.

Results

DORA-22 treated group had seizures at week-1 but none at months 1-3. TBI reduced amplitude and frequency of miniature inhibitory synaptic currents (mIPSCs) in dentate granule cells and these changes were rescued by DORA-22 treatment. Sleep analysis showed that DORA-22 increased non-rapid eye movement sleep (NREM) in the first 4hours of lights-off whereas THIP increased REM sleep in the first 4-hours of lights-on in week-1, At month-1 both treatments reduced time in NREM during lights-off. TBI increased NREM delta power (NΔ) along with loss of the homeostatic overnight decline of NΔ in week-1 regardless of treatment. DORA-22 and THIP treatment restored NΔ to levels similar to no craniotomy animals at month-1.

Conclusions

DORA-22 treatment suppressed posttraumatic seizures possibly due to enhanced GABAergic inhibition in dentate granule cells. DORA-22 may have therapeutic potential in suppressing PTE.

Summary for Social Media

Traumatic brain injury (TBI) can result is posttraumatic epilepsy and sleep disturbances. There are no treatments to prevent these complications. We tested whether treatment with sleep aids after TBI can mitigate seizures and sleep disturbances. We found that a sleep aid DORA-22 but not THIP suppressed post traumatic seizures possibly be enhancing GABAergic inhibition in the hippocampus. Sleep analysis showed that TBI disrupts the sleep homeostatic drive and DORA treatment restored it. Findings may lead to potential disease modifying therapy for posttraumatic epilepsy.
Exploring customer stewardship behaviors in service firms
Authors: Boateng Henry , Amenuvor Fortune Edem , Adam Diyawu Rahman , Agbemabiese George Cudjoe , Hinson Robert E.
Published: April 2022

Purpose

The existing literature has emphasized the importance of frontline service employees developing a sense of ownership for the overall well-being of customers. However, studies into why frontline service employees develop ownership and responsibility for customers are still lacking. The purpose of this paper is to address the question, “Why do frontline service employees engage in responsible customer service behaviors and protect the interests of customers in Ghana?"

Design/methodology/approach

A semistructured interview with 61 frontline service employees was used in the study. This study used a thematic analysis technique to analyze the data.

Findings

The findings show that frontline service employees develop a sense of customer stewardship because of organizational values, human resource management initiatives (rewards and in-service training) and ownership and accountability.

Originality/value

Studies on why frontline service employees engage in responsible customer service behaviors and protect the interests of customers is limited. This study addresses this gap in the literature.
Applying pricing research in B2B financial service industries
Authors: Indounas Kostis
Published: April 2022

Purpose

The purpose of this research paper is to investigate the extent to which companies that operate in business-to-business (B2B) financial service markets adopt any form of pricing research along with the different pricing objectives that they pursue in comparison with companies that do not adopt such kind of research.

Design/methodology/approach

To achieve the research objectives, data were collected from 143 companies operating in three different B2B financial service industries.

Findings

The findings of the study indicate that companies that adopt any form of pricing research are mainly based on historical sales data and personal in-depth interviews. Moreover, they focus more on both company and market related pricing objectives than those companies that do not adopt such pricing research methods when setting their prices.

Practical implications

The above findings indicate that the managers responsible for setting prices within their firms might have to gain a lot by adopting a research orientation when setting their prices, since such orientation may lead them to a more holistic approach regarding pricing decision-making by focusing on both company and market related issues.

Originality/value

Given the lack of similar studies in the existing B2B financial services literature, the value of the paper is that it represents one of the first attempts to empirically examine this issue.
Short-run effects of hurricanes on the housing markets: evidence from Florida
Authors: Dogan Can , Hattapoglu Mustafa , Hoxha Indrit
Published: April 2022

Purpose

Many studies have shown that the intensity and the number of hurricanes are likely to increase. This paper aims to look at the immediate effects of hurricanes on the time on the market, share of houses sold and percentage of houses with price cuts in the housing market using the metropolitan statistical area-level data in Florida.

Design/methodology/approach

Using a difference-in-difference method, the authors estimate the impact that a hurricane has on the housing markets.

Findings

The authors find that a hurricane has a positive and significant effect on the time on the market. A hurricane leads to a delay of the sale of a typical house in Florida by five days. The authors test for within-year seasonality and show that these effects change with seasonality of the housing market. Markets with seasonal housing prices tend to be affected more by hurricanes than those where housing prices are not seasonal. The authors also show that effects of a hurricane are transient and fade away in a few months. The results remain significant as the hurricane intensity changes.

Originality/value

This is the first study to look at the short-term effects of the hurricanes and how their effects vary based on seasonality of the markets.
Research on electronic word-of-mouth for product and service quality improvement: bibliometric analysis and future directions
Authors: Wang Yajun , Meng Xinyu , Xu Chang , Zhao Meng
Published: April 2022

Purpose

This paper aims to analyze high-quality papers on the research of electronic word-of-mouth (eWOM) for product and service quality improvement from 2009 to 2022, in order to fully understand their historical progress, current situation and future development trend.

Design/Methodology/Approach

This paper adopts the bibliometrics method to analyze the relevant literature, including publishing trend and citation status, regional and discipline area distribution, and influential publications. Secondly, the VOSviewer is used for literature co-citation analysis and keyword co-occurrence analysis to obtain the basic literature and research hotspots in this research field.

Findings

Firstly, the study finds that the number of publications basically shows an increasing trend, and those publications are mainly published in tourism journals. In addition, among these papers, China has the largest number of publications, followed by the USA and South Korea. Through co-citation analysis of literature and keyword co-occurrence analysis, 22 foundational papers and six main research topics are obtained in this paper. Finally, this paper elaborates on the development trend of the research topic and future research directions in detail.

Originality/value

This is the first paper that uses bibliometrics to analyze and review relevant researches on eWOM for product and service quality improvement, which is helpful for researchers to quickly understand its development status and trend. This review also provides some future research directions and provides a reference for further research.
Fostering firm resilience through organizational ambidexterity capability and resource availability: amid the COVID-19 outbreak
Authors: Gayed Salma , El Ebrashi Raghda
Published: April 2022

Purpose

This study aims to study the impact of organizational ambidexterity capability and resource availability on firm resilience along with perceived environmental uncertainty playing a moderating role. This study also intends to investigate the interplaying relationship between exploration capability and exploitation capability as components of organizational ambidexterity with resource availability.

Design/methodology/approach

Quantitative data was collected through self-administered surveys targeting 202 firms in Egypt. SEM (AMOS-SPSS) was used to test the proposed hypotheses.

Findings

The results indicated that both organizational ambidexterity capability and resource availability impact firm resilience. Moreover, the relationship between the enablers was found to be significant, where resource availability has a positive impact on the firm’s exploitation capability, the firm’s exploitation capability has a positive impact on its exploration capability and finally, the firm’s exploration capability has a positive impact on resource availability. However, the moderating role of perceived environmental uncertainty was found to be insignificant.

Research limitations/implications

Nonprobability convenience sampling technique, cross-sectional design and the relatively small sample size may hinder the ability to generalize this study.

Practical implications

This study identifies the importance of exploration (innovation) and exploitation (efficiency) capabilities for managers to build responsive organizations.

Originality/value

This study contributes to the understanding of firm resilience in times of uncertainties, where empirical research has not been enough. In addition, this study contributes to the identification of possible antecedents of firm resilience, highlighting the importance of certain strategic features including organizational ambidexterity capability and resource availability. This study also investigates the relationship between exploitation capabilities, exploration capabilities and resource availability, which was not empirically tested in the literature.
Fostering self-regulation and engaged exploration during the learner-content interaction process: the role of scaffolding in the online inquiry-based learning environment
Authors: Mamun Md Abdullah Al
Published: April 2022

Purpose

This study aims to present a scaffolding framework incorporating sophisticated technology that can inform instructional design to support student inquiry learning in the self-regulated online environment.

Design/methodology/approach

The classic predict, observe and explain (POE) framework has been extended through the incorporation of an additional evaluate (E) phase into the model to enhance the self-regulated online learning environment. The extended POEE scaffolding approach, in this study, has been conceptualized as an implicit guide to support the process of guided inquiry for learning particular science concepts. Digital tools were sourced and integrated into this design framework to substitute for the support typically offered by teachers and peers in classrooms.

Findings

The findings suggest that the POEE pedagogical design facilitated the inquiry process through promoting self-regulation and engaged exploration. It also promoted positive emotions in students towards the scaffolded learning modules.

Originality/value

Integrating technologies that benefit students differentially in educational settings remains a considerable challenge. More specifically, in science education, an appropriate inquiry learning context that allows access to well informed pedagogical design is imperative. The application of this inquiry-based scaffolding framework can inform educators in the process of creating their own instructional designs and contexts to provide more effective guided learning.
The linkage between international dairy commodity prices and volatility: a panel-GARCH analysis
Authors: Rezitis Anthony N. , Tremma Ourania A.
Published: April 2022

Purpose

The study's purpose is to investigate the price volatility of four dairy commodities (skim milk powder [SMP], whole milk powder [WMP], butter and cheddar cheese) in the three most significant regional markets (EU, Oceania and US) in the international dairy market.

Design/methodology/approach

The study uses a panel-Generalized Autoregressive Conditional Heteroskedastic (panel-GARCH) modeling technique and data from January 12, 2001, to April 28, 2017.

Findings

Conditional volatility was higher during subperiods 2007–2010 and 2014–2016 when conditional cross-correlations between prices had the lowest values. In some cases, they were negative (i.e. between the EU and the USA and between Oceania and the USA for both butter and cheese). Interdependence across the three dairy markets, especially for SMP and WMP markets and for the butter market between EU and Oceania is also strongly evidenced. Interdependence is responsible for the spillover of price shocks across the three regions.

Research limitations/implications

The data set used should be extended to cover the COVID-19 pandemic period.

Originality/value

This is the first study to use panel-GARCH to examine international dairy prices and volatility linkages, where previous studies mainly used multivariate GARCH models. Panel-GARCH allows a high-dimensional data series (i.e. 12 dairy prices) and generates potential efficiency gains in estimating conditional variances and covariances by incorporating information about heterogeneity across markets and considering their interdependence.
A business cycle model with money-in-utility (MIU) and government sector: the case of Bulgaria (1999–2020)
Authors: Vasilev Aleksandar
Published: April 2022

Purpose

The author augments an otherwise standard business cycle model with a richer government sector and adds money-in-utility (MIU) considerations to study economic fluctuations.

Design/methodology/approach

More specifically, real money balances enter in a non-separable way with consumption and leisure. This specification is then calibrated to Bulgarian data after the introduction of the currency board (1999–2020) gives a role to money in accentuating economic fluctuations.

Findings

This novel mechanism allows the framework to reproduce – better than the real business cycle (RBC) model – the observed variability and correlations among model variables, and those characterizing the labor market in particular. In addition, money is non-neutral and affects aggregate economic activity.

Originality/value

This is the first micro-founded monetary-DSGE (dynamic stochastic general equilibrium) model on Bulgaria trying to explain the role of money for economic fluctuations.
Choosing jobs over entrepreneurship: how do negative emotions demotivate the aspiring entrepreneurs?
Authors: Sharma Shalaghya , Kumar Amit
Published: April 2022

Purpose

The purpose of this research paper is to understand the effect of negative emotions created from social interactions on the aspiring entrepreneurs. The government of India has recently started several entrepreneurship development schemes to promote entrepreneurship among Indian youth, but still, the turnout rate tends to be low in some eastern states. A lot of research has been done about the various motivating factors, but less attention has been paid on the social interactions that create negative emotions. Unless researchers and government focus on the value of these negative emotions as corroders of motivation, it would be hard to accomplish the goals of an entrepreneurship-oriented country.

Design/methodology/approach

Interviews were conducted with participants of an entrepreneurship development program at the commencement of program and after one year.

Findings

It was found via the study that social interaction plays a crucial role in determining their motivation toward becoming an entrepreneur. Apart from this feeling of shame, fear, vulnerability, resentment, loneliness and self-doubt are crucial negative emotions that are corroding the chances of entrepreneurship among the Indian youth.

Research limitations/implications

The sample size was small to conduct a quantitative analysis. If a study could be conducted on a larger scale, it would contribute immensely to the entrepreneurship literature.

Social implications

It is a strong reminder of how the society can help in promoting entrepreneurship.

Originality/value

The impact of social interactions on the motivation of budding entrepreneurs has not been studied as per the literature review.
An investigation of individual willingness to pay ransomware
Authors: Cartwright Anna , Cartwright Edward , Xue Lian , Hernandez-Castro Julio
Published: April 2022

Purpose

Ransomware is a relatively new form of financial extortion that is proving a major cyber-security threat to individuals and organisations. This study aims to investigate factors that may influence an individual's willingness to engage in a ransom payment.

Design/methodology/approach

This study ran a large survey (n = 1,798) on a representative sample of the UK population. This study elicited willingness to pay (WTP) ransomware and also reasons for not wanting to pay a ransom to criminals. This study then used non-parametric tests and regression analysis to identify factors that influence WTP.

Findings

This study finds that women and younger age groups are significantly more willing to pay a ransom, as are those who store photos. There is a strong positive relationship between concern for data breach and WTP a ransom.

Originality/value

To the best of the authors’ knowledge, this is the first large scale study to look at WTP ransomware. This study identifies a range of factors that can help inform law enforcement to target advice about ransomware attacks.
Maturity model toll to diagnose Industry 4.0 in the clothing industry
Authors: Dal Forno Ana Julia , Bataglini Walakis Vieira , Steffens Fernanda , Ulson de Souza Antonio Augusto
Published: April 2022

Purpose

The purpose of this paper is to present a diagnostic instrument of the maturity of Industry 4.0 technologies adapted to the textile and clothing sector and constructed based on the technological references that support this industrial evolution process.

Design/methodology/approach

The proposed methodology began with the systematic literature review using the SciMAT software and then a questionnaire was developed with 49 questions divided into 5 categories – demography, technologies, strategy, digital skills and benefits of the deployment.

Findings

The application in 19 different sectors and 72 people in a textile industry showed this sector is still traditional. The diagnosis results pointed that the level of implementation of Industry 4.0 is considered the first level, later advancing in this order to levels of connectivity, visibility, predictability and adaptability of the processes.

Research limitations/implications

Only in one company was applied the developed instrument, in this case study, a factory that makes children's and adult clothing items located in Santa Catarina, Brazil.

Practical implications

Through the use of this assessment instrument, it is possible to perform an internal benchmarking at the company detecting the strong and weak points, as well as involve a multidisciplinary collaborator team.

Social implications

The comparisons and improvements may be carried out per dimension or sector, which motivates the constant application and assessment of improvements. The instrument to diagnose the maturity of Industry 4.0 technologies in the textile and clothing sector is considered an effective tool for application in a single company or to have its use expanded in a new piece of research to the entire industrial textile segment.

Originality/value

The developed diagnostic tool may be used for both the internal assessment of the company and its placement relative to its competitors, involving several companies from the same sector. It is possible to know about what level of Industry 4.0 maturity the company is and after benchmarking by others and improve.
Understanding tourist behaviour towards destination selection based on social media information: an evaluation using unsupervised clustering algorithms
Authors: Ghosh Prosenjit , Mukherjee Sabyasachi
Published: April 2022

Purpose

The study aims to cluster the travellers based on their social media interactions as well as to find the different segments with similar and dissimilar categories according to traveller's choice. The study also aims to understand the behaviour of clusters of the travellers towards destination selection and accordingly make the tour packages in order to improve tourists' satisfaction and gain viable benefits.

Design/methodology/approach

Agglomerative hierarchical clustering with Ward's minimum variance linkage algorithm and model-based clustering with parameterized finite Gaussian mixture models has been implemented to achieve the respective goals. The dimension reduction (DR) technique was introduced for better visualizing clustering structure obtained from a finite mixture of Gaussian densities.

Findings

A total of 980 travellers have been clustered into 8 different interest groups according to their tourism destinations selection across East Asia based on individual social media feedback. For selecting the optimal number of clusters as well as the behaviour of the interested travellers groups, both these proposed methods have shown remarkable similarities. DR technique ensures the reduction in dimensionality with seven directions, of which the first two directions explained 95% of total variability.

Practical implications

Tourism organizations focus on marketing efforts to promote the most attractive benefits to the clusters of travellers. By segmenting travellers of East Asia into homogeneous groups, it is feasible to choose a similar area to test different marketing techniques. Finally, it can be identified to which segments, new respondents or potential clients belong; consequently, the tourism organizations can design the tour packages.

Originality/value

The study has uniqueness in two aspects. Firstly, the study empirically revealed tourists' experience and behavioural intention to select tourism destinations and secondly, it finds quantifiable insights into the tourism phenomenon in East Asia, which helps tourism organizations to understand the buying behaviours of tourists' segments. Finally, the application of clustering algorithms to achieve the purpose of this study and the findings are very new in the literature on tourism, to understand the tourist behaviour towards destination selection based on social media reviews.
A sustainable circular 3D printing model for recycling metal scrap in the automotive industry
Authors: de Mattos Nascimento Daniel Luiz , Mury Nepomuceno Renan , Caiado Rodrigo Goyannes Gusmão , Maqueira Juan Manuel , Moyano-Fuentes José , Garza-Reyes Jose Arturo
Published: April 2022

Purpose

Industries and businesses are pursuing Industry 4.0 technologies as well as adopting a circular approach focused on improving manufacturing processes through the reduction of wastes, CO2 emissions and mineral exploration to mitigate the impact of climate change. In this sense, additive manufacturing (AM), often referred to as 3D printing, can play a key role in the closed-loop of operations. However, academics and practitioners have scarcely discussed the feasibility of implementing AM alongside circular economy (CE) practices, the techniques and methods that this would require, or how AM could benefit sustainability and circularity. To address these gaps, this paper proposes a novel circular sustainable 3D printing model for scrap recycling in the automotive industry.

Design/methodology/approach

The methodology uses a literature review-based approach followed by empirical research using metal scraps as the raw material for fabricating a powder to input a metal 3D printer for generating sustainable automotive components. A conceptual sustainable circular model for the automotive industry is proposed. Next, is conducted a focus group comprises AM and automotive industry experts for evaluations.

Findings

The results indicate that the proposed model can be used to reintroduce waste back into the manufacturing chain as raw material for the on-demand manufacture and supply of automotive components and that it may also have social and environmental implications.

Originality/value

This paper’s contributions are threefold: it explores the combined use of Industry 4.0 (I4.0), CE and sustainability in the automotive industry, develops a new model to support the circularity and sustainability of the scrap chain and proposes the use of AM as a catalyst of CE practices by reproducing recycled components with a 3D printer for prototypes or fully functioning components.