bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis
Authors: Peters Ruth , Xu Ying , Antikainen Riitta , Beckett Nigel , Gussekloo Jacobijn , Jagger Carol , Jukema Johan Wouter , Keinanen-Kiukaanniemi Sirkka , Rydén Lina , Skoog Ingmar , Staessen Jan A. , Thijs Lutgarde , Trompet Stella , Tully Philip J. , Tzourio Christophe , Anstey Kaarin J.
Published: October 2021

Introduction: Although increased cholesterol level has been acknowledged as a risk factor for dementia, evidence synthesis based on published data has yielded mixed results. This is especially relevant in older adults where individual studies report non-linear relationships between cholesterol and cognition and, in some cases, find higher cholesterol associated with a lower risk of subsequent cognitive decline or dementia. Prior evidence synthesis based on published results has not allowed us to focus on older adults or to standardize analyses across studies. Given our ageing population, an increased risk of dementia in older adults, and the need for proportionate treatment in this age group, an individual participant data (IPD) meta-analysis is timely. Method: We combined data from 8 studies and over 21,000 participants aged 60 years and over in a 2-stage IPD to examine the relationship between total, high-density, and low-density lipoprotein (HDL and LDL) cholesterol and subsequent incident dementia or cognitive decline, with the latter categorized using a reliable change index method. Results: Meta-analyses found no relationship between total, HDL, or LDL cholesterol (per millimoles per litre increase) and risk of cognitive decline in this older adult group averaging 76 years of age. For total cholesterol and cognitive decline: odds ratio (OR) 0.93 (95% confidence interval [CI] 0.86: 1.01) and for incident dementia: OR 1.01 [95% CI 0.89: 1.13]. This was not altered by rerunning the analyses separately for statin users and non-users or by the presence of an APOE e4 allele. Conclusion: There were no clear consistent relationships between cholesterol and cognitive decline or dementia in this older adult group, nor was there evidence of effect modification by statin use. Further work is needed in younger populations to understand the role of cholesterol across the life-course and to identify any relevant intervention points. This is especially important if modification of cholesterol is to be further evaluated for its potential influence on risk of cognitive decline or dementia.
Molecular Profiling in Pancreatic Cancer: Current Role and Its Impact on Primary Surgery
Authors: Mota Reyes Carmen , Doğruöz Alper , Istvanffy Rouzanna , Friess Helmut , Ceyhan Güralp O. , Demir Ihsan Ekin
Published: October 2021

Background: The advent of next-generation sequencing technologies has enabled the identification of molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) with different biological traits and clinically targetable features. Summary: Although current chemotherapy trials are currently exploiting this knowledge, these molecular subtypes have not yet sufficiently caught the attention of surgeons. In fact, integration of these molecular subtypes into the timing of surgery can in theory improve patient outcome. Here, we present the molecular subtypes of PDAC from the surgeon’s perspective and a clinically applicable algorithm that integrates the molecular subtyping of PDAC preoperatively into the decision of primary surgery versus neoadjuvant therapy. Furthermore, we point out the potential of “tailored” (in addition to conventional) neoadjuvant treatment for exploiting the molecular subtypes of PDAC. Key Messages: We believe that for surgeons, the preoperative knowledge on the subtype of PDAC can properly guide in deciding between upfront surgery versus neoadjuvant treatment for improving patient outcome.
Delay aware downlink resource allocation scheme for future generation tactical wireless networks
Authors: Shankar H. Ravi , Patil Kiran Kumari
Published: October 2021

For a very long time protecting physical border integrity is considered to be a challenging thing. Government organizations must provide trade operations for economic growth and at the same time must prevent malicious activity. A different resource such as drones, sensors, and radars are used for monitoring border areas which must be communicated to the remote border security force. Efficient wireless communication is required for communicating information. However, these devices cannot connect to a centralized network directly; thus, are connected in an ad-hoc fashion to connect centralized server. Different tactical network applications require different quality of service (QoS); hus efficient resource scheduling plays a very important role. Existing resource scheduling adopting deep learning and reinforcement techniques fails to meet the quality of experience (QoE) of the user and doesn’t assure access fairness among contending users. Further, require network information in prior and induce high training time. For overcoming research issues, this paper presents a delay-aware downlink resource scheduling (DADRA) technique for future generation networks. The optimization problem of reducing buffer overflow and improving scheduling QoS performance is solved using a genetic algorithm with an improved crossover function. Experiment outcome shows DADRA achieves much better throughput, slot utilization, and packet failure performance when compared with standard resource allocation technique.
Measuring scientific collaboration in co-authorship networks
Authors: Mahmood Basim , A. Sultan Nagham , H. Thanoon Karam , S. Kadhim Dheyaa
Published: October 2021

Scientific research is currently considered one of the key factors in the development of our life. It plays a significant role in managing our business, study, and work more conveniently. One of the important aspects when it comes to scientific research is the level of collaboration among researchers/disciplines. The collaboration between two different disciplines contributes to obtaining more reliable solutions for our everyday issues. Therefore, it is needed to understand the collaboration patterns among researchers and come up with convenient strategies for strengthening this kind of collaboration. In this work, we aim at investigating the patterns of scientific collaboration among researchers across disciplines. To this end, we generate a co-authorship network for several disciplines. The generated network reveals many interesting facts regarding the collaboration patterns among researchers who work in the same/different disciplines. We involve several measurements in this study that evaluate different aspects, which is of interest to the research communities since most of the studies in the literature measure specific aspects. Moreover, we propose a novel metric for measuring scientific collaboration in a research community and use it to benchmark the collaboration among disciplines. Finally, we use the obtained results/facts in providing recommendations for scientific communities.
Automated vision based defect detection using gray level co-occurrence matrix for beverage manufacturing industry
Authors: Mohd Saad Norhashimah , Abdullah A. R. , Hasan W. H. W. , Rahman N. N. S. A. , Ali N. H. , Abdullah I. N.
Published: October 2021

Defect inspection emerged as an important role for product quality monitoring process since it is a requirement of International Organization for Standardization (ISO) 9001. The used of manual inspection is impractical because of time consuming, human error, tiredness, repetitive and low productivity. Small and medium enterprises (SMEs) are industries that having problems in maintaining the quality of their products due to small capital provided. Therefore, automatic inspection is a promising approach to maintain product quality as well as to resolve the existing problems related to delay outputs and cost burden. This article presents a computerized analysis to detect color concentration defects that occur in beverage production based on texture information provided by gray level co-occurrence matrix (GLCM). Based on the texture information, GLCM cross-section is computed to extract the parameters for features of color concentration. The distance value between two colors is then computed using co-occurrence histogram. The defect results either pass or reject is determined using Euclidean distance and rule-based classification. The experimental results show 100% accuracy which makes the proposed technique can implimented for beverage manufacturing inspection process.
A general framework for selecting appropriate criteria of student as research assistant using fuzzy delphi method
Authors: Abd Anter Sulaiman , Rahmatullah Bahbibi , Hamad Khaleefah Shihab , Tamrin Khairul Fikri
Published: October 2021

This research aims to build a general framework for choosing the most appropriate set of criteria for recruiting student as a research assistant in a university research project. University researchers could benefit from such a framework because it could optimize the costs of research while also enhancing students research skills. In the same time, it is also essential that the quality of research ought to measure up to the grants provided by the university. Nevertheless, it is a challenging problem for many research supervisors in the selection of qualified research assistants. In this paper, we attempted to resolve this problem by building a general framework for selecting the appropriate criteria in the evaluation of student performance. We explored earlier studies on the proposed evaluation criteria of the research assistant and identified 47 most impactful criteria criteria. We obtained experts in engineering and information technology fields from two universities to answer questionnaires to identify their commonly used criteria for grant research assistant (GRA). Then, all the identified criteria were evaluated using the fuzzy delphi method (FDM) for finding the best fitting criteria which resulted in 16 most impactful criteria.
River classification and change detection from landsat images by using a river classification toolbox
Authors: Puttinaovarat Supattra , Saeliw Aekarat , Pruitikanee Siwipa , Kongcharoen Jinda , Chai-Arayalert Supaporn , Khaimook Kanit , Horkaew Paramate
Published: October 2021

Water bodies especially rivers are vital to existence of all lifeforms on Earth. Therefore, monitoring river areas and water bodies is essential. In the past, the monitoring relied essentially on manpower in surveying individual areas. However, there are limitations associated wih such surveys, e.g., tremendous amount of time and labour involved in expeditions. Presently, there have been accelerated development in remote sensing (RS) and artificial intelligence (AI) technology, particularly for change monitoring and detection in different areas globally. This research presents technical development of a toolbox for rivers classification and their change detection from Landsat images, by using water index analysis and four machine learning algorithms, which are K-Means, ISODATA, maximum likelihood classification (MLC), and support vector machine (SVM). Experimental findings indicated that all presented techniques were effective in detecting hydrological changes. The most accurate algorithm, nevertheless, for river classification was the SVM, with accuracy of 96.89%, precision of 98.61%, recall of 96.59%, and F-measure of 97.59%. Herein, it was demonstrated, in addition, that the developed toolbox was versatile and could be applied in rapid river change detection in other areas.
Requerimento administrativo prévio e judicialização da saúde pública: uma análise do requisito e de suas exceções
Authors: Spina Guilherme Malaguti , Magajewski Fabio Luparelli
Published: October 2021

O estudo analisou em que medida o requerimento administrativo prévio deve condicionar o acesso à justiça em demandas sobre saúde pública. Inicialmente, adotou-se o método dedutivo para, a partir da concepção de princípios presente na teoria dos direitos fundamentais de Robert Alexy, investigar a possibilidade de exigência desse pressuposto processual no contexto de colisão entre os princípios do acesso à justiça e os do devido processo legal instaurada para a proteção do direito fundamental à saúde. Em seguida, por meio do método indutivo, analisaram-se os fundamentos do julgamento do Supremo Tribunal Federal que condicionara o ajuizamento de ações previdenciárias ao requerimento administrativo prévio a fim de identificar se, consideradas as semelhanças e diferenças, essas razões seriam também aplicáveis, e em que medida, às demandas em matéria de saúde pública. Após, expuseram-se contribuições da adoção do prévio requerimento administrativo como requisito ao processamento de ações judiciais sobre saúde pública para o aprimoramento qualitativo da política pública sanitária, bem como para a prestação jurisdicional e a resolução adequada de conflitos nesse campo. Ao final, investigaram-se os limites e exceções a serem observados quanto à exigência de prévio requerimento administrativo em ações sobre saúde pública, com base na fundamentalidade do direito à saúde e nos parâmetros que vêm sendo consolidados na jurisprudência dos tribunais superiores, nos enunciados das Jornadas de Direito da Saúde e na literatura especializada.
New records of cheilostome Bryozoa from the eastern coast of India encrusting on the exoskeleton of live horseshoe crabs of Indian Sundarbans
Authors: Das Swati , Maria Susan Sanjay  , Basudev Tripathy  , C. Venkatraman  , K.A. Subramanian
Published: October 2021

Bryozoans are common commensal on hard surfaces and cover slow-moving animals like molluscans, sea turtles, brachyuran crabs, and horseshoe crabs. A total of six species of bryozoans belonging to four genus under three families of order Cheilostomatida were recorded encrusting on the carapaces of horseshoe crabs collected from Indian Sundarbans along the east coast of India and two among them, viz., Biflustra savartii (Audouin, 1826) and Sinoflustra arabianensis (Menon & Nair, 1975) are reported for the first time. Additionally, Jellyella tuberculata (Bosc, 1802) is reported for the first time from West Bengal coastal waters, previously known only from the Odisha coast of India. Both male and female horseshoe crabs were found to have been encrusted with bryozoan mats, although adequately not known about the life stages of their encrustation.
Population status of Heritiera fomes Buch.-Ham., a threatened species from Mahanadi Mangrove Wetland, India
Authors: Sahu Sudam Charan , Mohanta Manas Ranjan , N.H. Ravindranath
Published: October 2021

Heritiera fomes Buch.-Ham. is assessed as an endangered mangrove species by IUCN, and information on population status is lacking. The present study assesses the status of H. fomes in Mahanadi Mangrove Wetland on the east coast of India. Three forest blocks were selected and sampled for this study. Among these, the mean girth at breast height (GBH) of H. fomes was the highest in Hetamundia (HD) forest block. GBH of H. fomes was inversely proportional to the cumulative disturbance index (R2= 0.7244, p value <0.005). The relative density was maximum for H. fomes (56%) at Bhitarkharnasi (BK), and for Excoecaria agallocha at Hetamundia (HD; 35%) & Kansaridia (KD; 54%), respectively. Excoecaria agallocha is a dominant species possibly impacting natural populations of H. fomes. Climate change and rising sea levels may also negatively affect the existence of this species. Therefore, appropriate strategies should be taken for conservation of this globally threatened mangrove species prior to its extinction.
First record of the orb-weaving spider Araneus tubabdominus Zhu & Zhang, 1993 (Araneae: Araneidae) from India
Authors: Sen Souvik , Caleb John T.D. , Acharya Shelley
Published: October 2021

The Chinese species Araneus tubabdominus Zhu & Zhang, 1993 is recorded for the first time from India. A detailed redescription and illustrations of the female are provided along with a distributional map of the species.
Religionizing Christianity: Towards a Poststructuralist Notion of Global Religious History
Authors: Suarsana Yan
Published: October 2021

By relying on poststructural theory, this article will demonstrate how a consistent historicization can help us increase our understanding of how religious contexts changed in light of colonialism and globalization during the nineteenth century. While it is well known that such changes took place in non-Western regions, the article will show – by example of German liberal theology – that it was also in the so-called West that common systems of knowledge were transformed against the backdrop of global entanglement. On the basis of some prominent protagonists of so-called Culture Protestantism (Kulturprotestantismus), I will demonstrate how global debates led to a certain re-conceptualization of Christianity as a world religion in the late nineteenth century. By identifying different traditions such as Christianity or Buddhism as equivalent, those theologians supported the emerging global awareness of religion as a universal aspect of human life and a category sui generis.
The Postsecular – Jürgen Habermas, the Intellectual Dark Web, and Alexandr Dugin as (In)Voluntary Participants in a Global Dispositif
Authors: Okropiridze Dimitry
Published: October 2021

While being decipherable as a normative positing within a Euro-American genealogy, the conflictual discourse on “religion” and “science” should be seen as a potent globalized dispositif with local variants, ultimately shaping the reality of, not only active discourse participants, but all individuals, collectives, and institutions in its gravitational field.

In order to explore, examine, and attempt to explain both perspectives on the postsecular era – i.e., as an entity emerging from discursive articulations and a force acting upon discourse itself – three very different, yet conceptually related types of recent articulations and their discursive connection can be taken into account: first, Jürgen Habermas’ Eurocentric and Christocentric description of religion and science in the postsecular era; second, the so-called Intellectual Dark Web’s fusion of religious and scientific discourse elements via a Judeo-Christian narrative; third, Alexandr Dugin’s ethno-nationalist formulation of collective identities with a strong emphasis on religious elements and a fundamental opposition to the “West.”
A catalogue of Indian Arctiinae (Erebidae, Lepidoptera)
Authors: SINGH NAVNEET , JOSHI RAHUL , KIRTI JAGBIR SINGH , BISHT SANTOSH SINGH , PARAM HARSIMRANJEET SINGH
Published: October 2021

We present a catalogue of 673 species and nine subspecies of Indian Arctiinae in 175 genera which represents 6.11% of the global Arctiinae. Out of 673 species, a monogeneric tribe Amerilini is represented by four species (0.59 % of Indian Arctiinae and 6.06 % of global Amerilini), Arctiini are known by 180 species in 38 genera (26.74 % of Indian Arctiinae and 2.73% of global Arctiini), Lithosiini comprise 419 species in 128 genera (62.25% of Indian Arctiinae and 13.30% of global Lithosiini), and Syntomini account for 70 species in eight genera (10.40 % of Indian Arctiinae and 5.83% of global Syntomini). Information related to type localities, records from India with respective literature references, and the genus/ species synonyms is provided. Brief summaries for the four tribes of Indian Arctiinae, stating their Indian genus and species diversities, diagnostic characters of imagines are also provided. Furthermore, we present data on the distribution of the Arctiinae within the biogeographic zones of India. In addition, a brief analysis of the research history of Indian Arctiinae illustrates the general patterns of when and by whom the Indian species were described.
Epidicus by Plautus
Authors: Tracy Catherine
Published: October 2021

Epidicus, a light-hearted comedy by Plautus about the machinations of a trickster slave and the inadequacies of his bumbling masters, appears here in both its original Latin and a sparkling new translation by Catherine Tracy. Epidicus, the cunning slave, is charged with finding his master’s illegitimate daughter and the secret girlfriend of his master’s son, but a comedy of mistaken identities and competing interests ensues. Amid the mayhem, Epidicus aims to win his freedom whilst risking some of the grislier punishments the Romans inflicted on their unfortunate slaves.

This parallel edition in both Latin and English, with its accessible introduction and comprehensive notes, guides the reader through this popular Roman play. Tracy explores Epidicus’s roots in Greek drama, its rich social resonances for a Roman audience and its life in performance. She transforms Plautus' colloquial Latin poetry into lively modern English prose, illuminating the play’s many comedic references to the world of the Roman republic.

This fine introduction to an enduring play will be of great use and enjoyment for undergraduate students of Latin drama and the general reader alike.
Managing Turnover of STEM Teacher Workforce
Authors: Han Dongsook , Hur Hyungjo
Published: October 2021

We are facing a lack of skilled and certified STEM (science, technology, engineering, and math) teachers confined to schools with specific characteristics, such as working conditions and neighborhoods. It is essential to understand teachers’ decision-making processes that affect teacher turnover rates to enable schools to retain and motivate STEM. This study hypothesizes that lower job satisfaction concerning location and opportunities for advancement and independence is positively associated with voluntary leave from a school to another school or job switched from the K-12 teaching profession to other industries. We utilized a logit analysis for internal mobility if teachers remained in K-12 teaching but switch schools and external mobility if employed in non-education sectors using the National Survey of College Graduates data. The results varied by teacher experiences and mobility type. For novice STEM teachers, more opportunities for career advancements are needed to prevent external attrition. Internal mobility can be addressed via the overall improvement of the urban education environment and teacher compensation. Administrative support for experienced teachers’ career advancement should be considered. Government policies on STEM education need differentiated support considering teachers’ work experiences and working conditions.
Covid-19 Pandemic Management: Effects on Indian Economy—Reflections for Policy and Action Initiatives
Authors: Dhameja Nand L , Bobek Samo , Kapur Surbhi , Dhameja Manish
Published: October 2021

Pandemic is a type of epidemic that spreads over significant geographical areas and affects a large percent of population on a national or global level. Pandemic, as a project, has a lifecycle, a beginning and an end, though uncertain. The objective of the article is to trace various types of pandemics, to discuss their adverse effects of unemployment, distrust and loss of production. It presents various stimuli and remedial measures, a model to work out pandemic cost and its financial impact—estimated as ₹130 lakh crore in India. The article also gives an overview of positive results in the form of appreciations and acknowledgements, change in work culture resulting in work from home (WFH) approach. Financial restructuring resorted to by various business houses and future policy implications are also presented. The article is based on data drawn from government notifications and published reports. The study is exploratory, descriptive and analytical; it is presented in six parts.
The (Ir)Representability of the Belated Traumatic Wound in Lorraine Hansberry’s A Raisin in the Sun
Authors: Haj Sumaya
Published: October 2021

The dissociation of the traumatic moment from memory makes articulating the traumatic experience problematic. Henceforth, trauma becomes an inexplicable wound that can be narrated in a myriad of ways, yet none of which has a closure. The traumatized subjects are in need for expressing their pain, especially that telling one’s story and finding witnesses to the experience is therapeutic in the case of trauma. Thus, writers strive to represent their personal trauma and/or their collective one through various techniques to convey the experience as authentically as possible. Lorraine Hansberry’s A Raisin in the Sun is a remarkable endeavor to articulate the author’s own traumatic childhood experience, as well as the broader trauma of African American people who have suffered so long because of slavery and its aftermath. This paper argues that Hansberry’s A Raisin addresses trauma and represents it through four major techniques: the choice of drama as a genre, the mode of genuine realism, intertextuality, and symbolism. To realize this purpose, the study explores the play in light of the theoretical framework of trauma studies, starting from its outset with Freud’s essential concepts, and moving to Cathy Caruth’s and Shoshana Felman’s integral contributions to the field.
Teaching the Core Arts Standards in Modern Band
Authors: Clauhs Matthew , Powell Bryan
Published: October 2021

The National Coalition for Core Arts Standards released standards for music education in 2014. These standards are guided by artistic processes and measured by performance standards specific to content areas and grade levels. As school districts in the United States adopt the Core Arts Standards for their music programs, it is imperative that modern band teachers demonstrate how their curriculum aligns with this new framework. Modern band is one approach to popular music education that is particularly well suited to address this new framework; the emphases of songwriting, improvising, critical listening, and group work in a learner-centered modern band class/ensemble are associated with a wide variety of standards. This article explores connections between popular music pedagogies and each of the processes in the Core Arts Standards and examines which standards may be most appropriate for modern band contexts.
How effective are mobility subsidies in targeting the unemployed? Lessons from the Swedish Model, 1965–1975
Authors: Molinder Jakob
Published: October 2021

The Swedish Model on the labor market has been celebrated as a way to combine mobility with low unemployment and small wage gaps. As part of the model, relocation allowances were pioneered from the late 1950s. The program expanded thereafter and as much as 1% of the population in the high-unemployment north moved with assistance in the 1960s. Today, migration incentives are discussed to address pressing unemployment problems in Europe and the United States. What can Sweden’s experience tell us about the prospects of such programs? This article studies the usage of relocation allowances through a case study of Västernorrland County from 1965 to 1975. The analysis shows that there was a strong selection into the program by younger persons, recent graduates and from sectors with good employment prospects. The experience from Sweden highlights the difficulty of implementing programs to induce migration for those with the highest risk of unemployment.
Palliative care integration for patients with advanced chronic obstructive pulmonary disease (COPD): Identifying essential components using participatory action research
Authors: Fusi-Schmidhauser Tanja , Froggatt Katherine , Preston Nancy
Published: October 2021

Background:

Chronic obstructive pulmonary disease (COPD) is a life-limiting condition with palliative care needs. Despite increasing awareness about the role palliative care can play in care provision for patients with advanced COPD, integration in standard care remains underdeveloped. The unpredictability of the disease progression and misconceptions about palliative care being equivalent to end-of-life care often prevent a timely integrated approach in advanced COPD.

Aim:

To identify practices designed to increase integration of palliative care in the management of patients with advanced COPD in a respiratory service in Southern Switzerland.

Design:

A participatory action research approach was chosen and key stakeholders were involved to develop new knowledge and practices, supported by a Theory of Change framework. Data from each cycle and retrospective analysis at the end of the whole research were analysed using thematic analysis.

Setting/participants:

Five action research cycles with seven healthcare professionals working in palliative or respiratory care settings were conducted.

Results:

Three elements of integrated palliative care in advanced COPD were identified: multidimensional assessment, healthcare professionals’ education and interdisciplinary team meetings, which are the pillars of a new integrated palliative care model for patients with advanced COPD.

Conclusions:

The new integrated palliative care model in advanced COPD includes essential elements with a focus on patients, healthcare professionals and care delivery. Further research on testing this model in clinical practice, service development, implementation processes and possible outcomes, including evaluation of the financial impact of integrated palliative care is necessary to foster this care approach across all possible settings.
Relationship between depression, prefrontal creatine and grey matter volume
Authors: Faulkner Paul , Paioni Susanna Lucini , Kozhuharova Petya , Orlov Natasza , Lythgoe David J , Daniju Yusuf , Morgenroth Elenor , Barker Holly , Allen Paul
Published: October 2021

Background:

Depression and low mood are leading contributors to disability worldwide. Research indicates that clinical depression may be associated with low creatine concentrations in the brain and low prefrontal grey matter volume. Because subclinical depression also contributes to difficulties in day-to-day life, understanding the neural mechanisms of depressive symptoms in all individuals, even at a subclinical level, may aid public health.

Methods:

Eighty-four young adult participants completed the Depression, Anxiety and Stress Scale (DASS) to quantify severity of depression, anxiety and stress, and underwent 1H-Magnetic Resonance Spectroscopy of the medial prefrontal cortex and structural magnetic resonance imaging (MRI) to determine whole-brain grey matter volume.

Results/outcomes:

DASS depression scores were negatively associated (a) with concentrations of creatine (but not other metabolites) in the prefrontal cortex and (b) with grey matter volume in the right superior medial frontal gyrus. Medial prefrontal creatine concentrations and right superior medial frontal grey matter volume were positively correlated. DASS anxiety and DASS stress scores were not related to prefrontal metabolite concentrations or whole-brain grey matter volume.

Conclusions/interpretations:

This study provides preliminary evidence from a representative group of individuals who exhibit a range of depression levels that prefrontal creatine and grey matter volume are negatively associated with depression. While future research is needed to fully understand this relationship, these results provide support for previous findings, which indicate that increasing creatine concentrations in the prefrontal cortex may improve mood and well-being.
Kinematic Analysis of Lateral Meniscal Oblique Radial Tears in the Anterior Cruciate Ligament–Deficient Knee
Authors: Smith Patrick A. , Bezold Will A. , Cook Cristi R. , Krych Aaron J. , Stuart Michael J. , Wijdicks Coen , Cook James L.
Published: October 2021

Background:

Lateral meniscal oblique radial tears (LMORT) occur frequently in conjunction with anterior cruciate ligament (ACL) disruption and are anatomically distinct from meniscus root tears.

Hypothesis/Purpose:

The purpose of this study was to characterize the effects of LMORT types 3 (LMORT3) and 4 (LMORT4) lesions on joint stability and meniscal extrusion in ACL-deficient knees. Our hypothesis was that both lesions would promote significant increases in anterior translation and meniscal extrusion, with the LMORT4 lesion having a greater effect.

Study Design:

Controlled laboratory study.

Methods:

Two matched pairs of cadaveric knees (n = 4) were used to optimize the testing sequence. Additional cadaveric knees with LMORT3 (n = 8) and LMORT4 (n = 8) lesions created after ACL transection underwent robotic kinematic testing for anterior drawer and pivot-shift simulations with associated ultrasound-measured meniscal extrusion at clinically relevant knee flexion angles.

Results:

Optimization testing showed no differences on the effect of LMORT4 lesions for anterior translation and lateral meniscal extrusion with ACL-intact versus ACL-deficient knees. ACL deficiency and LMORT3 and LMORT4 lesions with ACL deficiency were associated with significantly greater anterior translation compared with ACL-intact state for both anterior drawer and pivot-shift testing at all flexion angles ( P < .001). ACL deficiency with either LMORT3 or LMORT4 lesion was associated with significantly greater anterior translation than was ACL deficiency only ( P < .005) for anterior drawer testing at 90° of flexion. Meniscal extrusion was greater with LMORT3 and LMORT4 lesions compared with ACL deficiency only ( P < .05) for anterior drawer at 60° of flexion and for pivot shift at 15° of flexion. The LMORT4 lesion demonstrated increased anterior translation for anterior drawer ( P = .003) at 60° of flexion (12%) as well as for pivot shift at 15° of flexion (7%) and 30° of flexion (13%) ( P < .005) compared with ACL deficiency only.

Conclusion:

In this cadaveric model, the addition of an LMORT3 or LMORT4 lesion increased anterior laxity for both the anterior drawer and the pivot shift when compared with an isolated ACL tear. Lateral meniscal extrusion was also exacerbated by these LMORT lesions.

Clinical Relevance:

LMORT lesions, distinct from meniscus root tears, occur frequently in conjunction with ACL tears. This study characterized the biomechanical consequences of LMORT3 and LMORT4 lesions on joint stability and meniscal function, highlighting the importance of diagnosing and treating LMORT lesions at the time of ACL reconstruction.
Summary of the 12th Meeting of the European Forum on antiphospholipid antibodies ONLINE
Authors: Djokovic Aleksandra , Stojanovich Ljudmila
Published: October 2021

As a result of the current COVID-19 pandemic, the 12th meeting of the European Forum on Antiphospholipid Antibodies was held in a digital format on 26th March 2021. Even experienced for the first time in a virtual set-up, it kept its strength in continuation of the opportunity for more than 200 physicians from all continents and 20 countries to meet the experts in the field. Contemporary research in the area of antiphospholipid syndrome was presented, and proposals for the new research projects, as a distinguishing feature of the meeting, made a major contribution. Despite challenging times, this meeting enabled the highest number of registered participants to have interactive communication with presenters. This report summarizes major studies and new research projects presented during the online forum meeting.
What Matters Most to Older Chinese Adults
Authors: Choi Liza Lai Shan , Jung Piera , Harder Marti , Zhang Kelly
Published: October 2021

Introduction:

Although an abundance of gerontological research has focused on subjective well-being, quality of life, and life satisfaction, we know little about what matters most to older adults in sub-cultural groups. The purpose of this study was to explore what matters to older Chinese adults.

Methods:

The study used a qualitative interpretive design, drawing influences from phenomenology and constructed meaning through participants’ lived experiences.

Results:

After data analysis, a core theme of cultural foundations and categorical themes emerged. This study emphasized the importance of hearing the voices of Chinese older adults and how they viewed well-being, quality of life, life satisfaction, and health care.

Discussion:

The findings of this study have added to the body of existing knowledge of what matters most to older adults. These insights may advance nursing as it pertains to culturally congruent health care.
Wave-based active vibration control of a membrane structure
Authors: Liu Xiang , Lv Liangliang , Peng Fujun , Cai Guoping
Published: October 2021

Wave-based active vibration control of a membrane structure by using the Active Sink Method is studied in this paper. Unlike the modal-based vibration control method which attempts to suppress several vibration modes that have already been excited, wave-based active controller can keep vibration modes inactive by stopping the formation of standing waves in the structure. First, the wave transfer matrix is deduced to characterize the wave transmission in the membrane structure. Then, feedforward wave control laws are derived analytically to absorb reflected waves or eliminate transmitted waves. The validity of the proposed active wave controllers is verified through numerical simulations. Simulation results show that by using the active wave controllers no standing waves will be produced in the structure, and the vibration of the membrane structure is suppressed significantly.
Adolescent Energy Drink Consumption and Academic Risk: Results From the Monitoring the Future Study, 2010–2016
Authors: Leal Wanda E. , Jackson Dylan B. , Boccio Cashen M.
Published: October 2021

Aims

The current study aims to examine the role of energy drink and energy shot consumption in school disengagement, low academic performance, and academic expectations, and investigates the robustness of these associations across sex, grade, race, and substance use history.

Method

This study employs a pooled cross-sectional design and uses a nationally representative sample of 8th (ages 13–14 years) and 10th (ages 15–16 years) grade adolescents from seven recent cohorts (2010–2016) of the Monitoring the Future study. Logistic regression and negative binomial regression were employed to examine the association between energy drink and energy shot consumption and academic risk factors, controlling for sociodemographic factors and other health and social behaviors. Ancillary robustness checks across key subgroups in the data were also performed.

Results

The results indicate that energy drink and energy shot consumers are significantly more likely to report all academic risk outcomes. Specifically, youth who heavily use energy drinks and shots have significantly higher odds of each of the academic risk outcomes relative to both less habitual users and nonusers. These patterns hold across subgroups, despite associations being somewhat stronger among females, younger participants, Whites, and youth with no substance use history.

Conclusions

The current study suggests that energy drink consumption (particularly heavy consumption) may be an early warning sign of academic risk. It may be beneficial to limit adolescent energy drink consumption, provide early intervention for heavy adolescent consumers, and raise awareness of the dangers associated with their use.
Distance Teaching of Psychology in Europe: Challenges, Lessons Learned, and Practice Examples During the First Wave of COVID-19 Pandemic
Authors: Sokolová Lenka , Papageorgi Ioulia , Dutke Stephan , Stuchlíková Iva , Williamson Morag , Bakker Helen
Published: October 2021

COVID-19 pandemic has affected many areas of our lives including education. In the time of designing this study most schools, colleges, and universities across Europe were closed and psychology educators were expected to change their teaching methods rather quickly. This study investigates how they coped with this situation, which technology and methods they used to teach psychology distantly, and which barriers and outcomes they found in this situation. Participants were N = 660 secondary school and university teachers from 28 European countries. The results showed that the participants across Europe face similar challenges in adopting distance teaching methods, which were technical and organizational rather than pedagogical. Despite the fact they found distance teaching of specific psychological contents challenging, psychology teachers also described positive aspects of distance teaching, examples of good practice and lessons learned that could be generally implemented in the teaching of psychology beyond the pandemic situation.
The logic of strategic entrepreneurship
Authors: Keyhani Mohammad
Published: October 2021

In this essay, I attempt to clarify the construct of strategic entrepreneurship from a new angle. By comparing the ideal-type theory of strategy without entrepreneurship with the ideal-type theory of entrepreneurship without strategy, I shed light on what it means to combine the logics of entrepreneurship and strategy and illustrate the value of their complementarity. The key insight is that entrepreneurship is blind without strategy and strategy is paralyzed without entrepreneurship. I further argue that many proponents of strategic entrepreneurship and action-based theories of strategy have prematurely given up on the idea of sustained competitive advantage. Disequilibrium and uncertainty do not automatically mean that no predictable and stable patterns can be relied upon for sustained competitive advantage.
Complicating College-Transition Stories: Strengths and Challenges of Approaches to Diversity in Wise-Story Interventions
Authors: Covarrubias Rebecca , Laiduc Giselle
Published: October 2021

In response to the growing numbers of minoritized students (e.g., low-income, first-generation, students of color) transitioning into U.S. systems of higher education, researchers have developed transition-assistance strategies, such as psychologically wise-story interventions. Through a rigorous, theory-driven approach, wise-story interventions use stories to encourage students to develop adaptive meanings about college-transition challenges, subsequently allowing students to persist. Yet there is one critical distinction between existing wise-story interventions. Well-known examples endorse a color-evasive message that all students, regardless of their demographic backgrounds, share similar struggles when adjusting to college. One variation in wise-story interventions ties transition struggles explicitly to students’ identities, adopting more of a multicultural perspective. Drawing from diversity frameworks, we offer in this article a comparative analysis of these variations; we outline under what conditions, for whom, and through which processes these varying approaches to identity affect student outcomes. In this discussion, we reflect on both the strengths and challenges of wise-story interventions and offer considerations for extending these approaches. Specifically, we ask whether integrating critical perspectives into wise-story interventions better addresses the experiences of minoritized students as they navigate institutions historically built for dominant groups.
A New Isoflavan From the Heartwood of Dalbergia cochinchinensis
Authors: Zhong Yanxia , Chen Jiao , Mo Xinliang , Xu Zhifang , Qiu Shengxiang , Liu Xinhong
Published: October 2021

A new isoflavan, named dalbergiacochan A (1), was isolated from the heartwood of Dalbergia cochinchinensis, along with two known isoflavans, namely mucronulatol (2) and 2′-O-methylsepiol (3). Their structures were elucidated based on extensive spectroscopic analyses, including one-dimensional (1D) and two-dimensional nuclear magnetic resonance (2D NMR), and mass spectroscopy (MS) data, and the absolute stereochemistry of compound 1 was determined as R-3′,6-dihydroxy-2′,4′,8-trimethoxyisoflavan from its circular dichroism spectrum. Compound 1 was inactive against Escherichia coli, Bacillus thuringiensis, and Shigella dysenteriae.
Association of BRCA1 and BRCA2 genes in arsenic-induced urinary bladder carcinoma
Authors: Jaiswal Alankar , Satardey Ritesh , Datta Chhanda , Panda Chinmay , Pal Dilip Kumar
Published: October 2021

Objective:

Study was performed to determine content of arsenic in urinary bladder tumour tissue and association of BRCA1 and BRCA2 protein expression with urinary bladder carcinoma development.

Materials and methods:

This study was performed in a tertiary care hospital of Eastern India. Post-operative tumour tissue was analysed for arsenic content as well as BRCA1 and BRCA2 expression. Statistical analysis was done and association between stage, grade and BRCA1 and BRCA2 expression with arsenic level in tumour tissue was done.

Results:

Total 50 patients were included in study. Out of which 26 were arsenic positive as well as 24 were arsenic negative. Maximum patients in arsenic positive group were from arsenic endemic zones of West Bengal, India. There was significant correlation between higher stage and grade of tumour and arsenic positivity. BRCA1 correlation was significant with arsenic positive group whereas BRCA2 correlation was not significant with arsenic positive group.

Conclusion:

Bladder carcinomas are more common in arsenic endemic zones of our country. This association can help in future to develop drugs which act on selected mutation of genes such as BRCA1, especially in arsenic-associated bladder cancers.
Clinicopathological characteristics of mucin phenotype and its relation to the malignant potential in early differentiated gastric adenocarcinoma
Authors: Akaishi Takanobu , Yoshizawa Tadashi , Morohashi Satoko , Goto Shintaro , Muroya Takahiro , Akasaka Harue , Hakamada Kenichi , Kijima Hiroshi
Published: October 2021

Objectives

Mucin phenotype is a tool to classify gastric cancer, but the relationship between mucin phenotype and its malignancy is still controversial. This study aimed to clarify the relationship between mucin phenotype and the malignant potential of gastric cancer.

Methods

A total of 82 cases of early-stage differentiated adenocarcinoma (submucosal invasion cases) obtained from surgeries were studied by immunohistochemistry. Gastric mucin phenotype and E-cadherin expression were analyzed in the mucosal and submucosal layer. E-cadherin expression was analyzed by using imaging software (ImageJ) for objective data analysis. Furthermore, the mucin phenotypic shift was analyzed from mucosa to submucosa.

Results

We found that: (1) tumors with intestinal mucin phenotype had statistically more venous invasion in the submucosal lesion; (2) tumors with an intestinal phenotype that showed venous invasion in the submucosal lesion had a higher percentage of tumors that showed loss of phenotype; (3) no dominant change in E-cadherin expression was observed from the mucosa to submucosa.

Conclusion

Tumors with loss of phenotype and submucosal intestinal phenotype showed predominantly more venous invasion, so examining the identification of phenotypes and phenotype shifts can be expected to be a factor that influences treatment strategies after endoscopic treatment or after surgical resection.