bluuebunny/crossref_metadata_2025 huggingface dataset:
The Mediating Influence of the Unified Theory of Acceptance and Use of Technology on the Relationship Between Internal Health Locus of Control and Mobile Health Adoption: Cross-sectional Study
Authors: Ahadzadeh Ashraf Sadat , Wu Shin Ling , Ong Fon Sim , Deng Ruolan
Published: July 2021

Background

Mobile health (mHealth) as an innovative form of information and communications technology can efficiently deliver high-quality health care by enhancing communication and health management, reducing costs, and increasing access to health services. An individual’s internal health locus of control (HLOC) is found to be associated with the behavioral intent to adopt mHealth. However, little is known about the underlying mechanism of this association.

Objective

The primary objective of this study was to test the mediation influence of the Unified Theory of Acceptance and Use of Technology (UTAUT) on the relationship between internal HLOC and the behavioral intention to use mHealth.

Methods

A total of 374 responses were collected from Malaysian adult users of mHealth, using convenience and snowball sampling methods. Partial least squares structural equation modeling was used to analyze the data. Data were collected for variables, including demographics, internal HLOC, and modified UTAUT constructs (ie, performance expectancy, effort expectancy, and social influence).

Results

The results showed that there was no direct relationship between internal HLOC and the behavioral intention to use mHealth (β=−0.039, P=.32). The indirect relationship between internal HLOC and the intent to adopt mHealth was supported, indicating that the UTAUT constructs performance expectancy (β=0.104, P<.001), effort expectancy (β=0.056, P=.02), and social influence (β=0.057, P=.002) mediated this relationship. The results showed full mediation, with total variance explained at 47.2%.

Conclusions

This study developed an integrative model, where a health-related disposition (internal HLOC), mHealth-related beliefs (performance expectancy and effort expectancy), and normative pressure (social influence) were combined to explain the underlying mechanism of the behavioral intent to adopt mHealth. The results showed that the intention to adopt mHealth is mediated by the influence of UTAUT factors, while HLOC has no direct effect on adoption intention. The findings provide insights into augmenting mHealth adoption among the public by enhancing the perceived benefits of mHealth, helping design more effective and user-friendly mHealth tools, and capitalizing on social normative influence to adopt mHealth. This study utilized the constructs of the UTAUT model to determine the intention to use mHealth. Future research should focus on other health- and technology-related theories to ascertain other possible factors influencing the behavioral intent of mHealth adoption.
Using Artificial Intelligence With Natural Language Processing to Combine Electronic Health Record’s Structured and Free Text Data to Identify Nonvalvular Atrial Fibrillation to Decrease Strokes and Death: Evaluation and Case-Control Study
Authors: Elkin Peter L , Mullin Sarah , Mardekian Jack , Crowner Christopher , Sakilay Sylvester , Sinha Shyamashree , Brady Gary , Wright Marcia , Nolen Kimberly , Trainer JoAnn , Koppel Ross , Schlegel Daniel , Kaushik Sashank , Zhao Jane , Song Buer , Anand Edwin
Published: July 2021

Background

Nonvalvular atrial fibrillation (NVAF) affects almost 6 million Americans and is a major contributor to stroke but is significantly undiagnosed and undertreated despite explicit guidelines for oral anticoagulation.

Objective

The aim of this study is to investigate whether the use of semisupervised natural language processing (NLP) of electronic health record’s (EHR) free-text information combined with structured EHR data improves NVAF discovery and treatment and perhaps offers a method to prevent thousands of deaths and save billions of dollars.

Methods

We abstracted 96,681 participants from the University of Buffalo faculty practice’s EHR. NLP was used to index the notes and compare the ability to identify NVAF, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack, vascular disease, age 65 to 74 years, sex category (CHA2DS2-VASc), and Hypertension, Abnormal liver/renal function, Stroke history, Bleeding history or predisposition, Labile INR, Elderly, Drug/alcohol usage (HAS-BLED) scores using unstructured data (International Classification of Diseases codes) versus structured and unstructured data from clinical notes. In addition, we analyzed data from 63,296,120 participants in the Optum and Truven databases to determine the NVAF frequency, rates of CHA2DS2‑VASc ≥2, and no contraindications to oral anticoagulants, rates of stroke and death in the untreated population, and first year’s costs after stroke.

Results

The structured-plus-unstructured method would have identified 3,976,056 additional true NVAF cases (P<.001) and improved sensitivity for CHA2DS2-VASc and HAS-BLED scores compared with the structured data alone (P=.002 and P<.001, respectively), causing a 32.1% improvement. For the United States, this method would prevent an estimated 176,537 strokes, save 10,575 lives, and save >US $13.5 billion.

Conclusions

Artificial intelligence–informed bio-surveillance combining NLP of free-text information with structured EHR data improves data completeness, prevents thousands of strokes, and saves lives and funds. This method is applicable to many disorders with profound public health consequences.
Sources of Health Information, Technology Access, and Use Among Non–English-Speaking Immigrant Women: Descriptive Correlational Study
Authors: Chae Steve , Lee Yoon-Jae , Han Hae-Ra
Published: July 2021

Background

As the world is becoming increasingly connected by the World Wide Web, the internet is becoming the main source of health information. With the novel COVID-19 pandemic, ubiquitous use of the internet has changed the daily lives of individuals, from working from home to seeking and meeting with health care providers through web-based sites. Such heavy reliance on internet-based technologies raises concerns regarding the accessibility of the internet for minority populations who are likely to already face barriers when seeking health information.

Objective

This study aims to examine the level of technology access and common modes of technology used by Korean American women and to investigate how key psychosocial determinants of health such as age, education, English proficiency, and health literacy are correlated with sources of health information used by Korean American women and by their use of the internet.

Methods

We used data from a subsample of Korean American women (N=157) who participated in a community-based randomized trial designed to test a health literacy–focused cancer screening intervention. In addition to descriptive statistics to summarize Korean American women’s internet access and common modes of technology use, we conducted backward stepwise logistic regression analyses to substantiate the association between the psychosocial determinants of health and internet use.

Results

Approximately two-thirds (103/157, 65.6%) of the sample had access to the internet, and nearly all had access to a mobile phone. The internet was the most commonly used channel to obtain health information 63% (99/157), and 70% (110/157) of the sample used text messaging. Nevertheless, only approximately 38.8% (40/103) of the sample were very confident in using the internet, and only 29.9% (47/157) were very confident in using text messaging. Multivariate analyses revealed that older age (>50 years) was associated with 79% lower odds of using the internet to seek health information (adjusted odds ratio [AOR] 0.21, 95% CI 0.10-0.46). The higher health literacy group (19+ on Rapid Estimate of Adult Literacy in Medicine) had 56% lower odds of using the internet to acquire health information (AOR 0.44, 95% CI 1.13-11.18). Higher education (college+) was associated with both internet use (AOR 4.42, 95% CI 1.88-9.21) and text messaging (AOR 3.42, 95% CI 1.55-7.54). Finally, English proficiency was associated with text messaging (AOR 4.20, 95% CI 1.44-12.24).

Conclusions

The differences in modes of technology access, use, and confidence by some of the key psychosocial determinants, as observed in our study sample, have important implications when health care teams develop dissemination plans.
Self-Focused and Other-Focused Health Concerns as Predictors of the Uptake of Corona Contact Tracing Apps: Empirical Study
Authors: große Deters Fenne , Meier Tabea , Milek Anne , Horn Andrea B
Published: July 2021

Background

Corona contact tracing apps are a novel and promising measure to reduce the spread of COVID-19. They can help to balance the need to maintain normal life and economic activities as much as possible while still avoiding exponentially growing case numbers. However, a majority of citizens need to be willing to install such an app for it to be effective. Hence, knowledge about drivers for app uptake is crucial.

Objective

This study aimed to add to our understanding of underlying psychological factors motivating app uptake. More specifically, we investigated the role of concern for one’s own health and concern to unknowingly infect others.

Methods

A two-wave survey with 346 German-speaking participants from Switzerland and Germany was conducted. We measured the uptake of two decentralized contact tracing apps officially launched by governments (Corona-Warn-App, Germany; SwissCovid, Switzerland), as well as concerns regarding COVID-19 and control variables.

Results

Controlling for demographic variables and general attitudes toward the government and the pandemic, logistic regression analysis showed a significant effect of self-focused concerns (odds ratio [OR] 1.64, P=.002). Meanwhile, concern of unknowingly infecting others did not contribute significantly to the prediction of app uptake over and above concern for one’s own health (OR 1.01, P=.92). Longitudinal analyses replicated this pattern and showed no support for the possibility that app uptake provokes changes in levels of concern. Testing for a curvilinear relationship, there was no evidence that “too much” concern leads to defensive reactions and reduces app uptake.

Conclusions

As one of the first studies to assess the installation of already launched corona tracing apps, this study extends our knowledge of the motivational landscape of app uptake. Based on this, practical implications for communication strategies and app design are discussed.
Empowering Anxious Parents to Manage Child Avoidance Behaviors: Randomized Control Trial of a Single-Session Intervention for Parental Accommodation
Authors: Sung Jenna Y , Mumper Emma , Schleider Jessica Lee
Published: July 2021

Background

A majority of youth who need anxiety treatment never access support. This disparity reflects a need for more accessible, scalable interventions—particularly those that may prevent anxiety in high-risk children, mitigating future need for higher-intensity care. Self-guided single-session interventions (SSIs) may offer a promising path toward this goal, given their demonstrated clinical utility, potential for disseminability, and low cost. However, existing self-guided SSIs have been designed for completion by adolescents already experiencing symptoms, and their potential for preventing anxiety in children—for instance, by mitigating known anxiety risk factors—remains unexplored.

Objective

This trial evaluated the acceptability and proximal effects of project EMPOWER: a web-based, self-guided SSI designed to reduce parental accommodation, a parenting behavior known to increase the risk of anxiety in offspring.

Methods

In total, 301 parents who reported elevated anxiety symptoms with children aged 4-10 years received either project EMPOWER or an informational control (containing psychoeducational materials and resources); parents self-reported their accommodation of child anxiety and overall distress tolerance at baseline and 2-week follow-up.

Results

Relative to control-group parents, those who received the intervention outlined in project EMPOWER reported significant reductions in their accommodation of child anxiety (ds=0.61; P<.001) and significant increases in their distress tolerance (ds=0.43; P<.001) from baseline to 2-week follow-up. Additionally, parents rated project EMPOWER as highly acceptable (ie, easy to use, helpful, and engaging) in accordance with preregistered benchmarks.

Conclusions

Project EMPOWER is an acceptable self-guided SSI for parents of children at-risk for anxiety, which yields proximal reductions in clinically relevant targets.

Trial Registration

ClinicalTrials.gov NCT04453865; https://tinyurl.com/4h84j8t9
Health Information Systems for Older Persons in Select Government Tertiary Hospitals and Health Centers in the Philippines: Cross-sectional Study
Authors: Garcia Angely P , De La Vega Shelley F , Mercado Susan P
Published: July 2021

Background

The rapid aging of the world’s population requires systems that support health facilities’ provision of integrated care at multiple levels of the health care system. The use of health information systems (HISs) at the point of care has shown positive effects on clinical processes and patient health in several settings of care.

Objective

We sought to describe HISs for older persons (OPs) in select government tertiary hospitals and health centers in the Philippines. Specifically, we aimed to review the existing policies and guidelines related to HISs for OPs in the country, determine the proportion of select government hospitals and health centers with existing health information specific for OPs, and describe the challenges related to HISs in select health facilities.

Methods

We utilized the data derived from the findings of the Focused Interventions for Frail Older Adults Research and Development Project (FITforFrail), a cross-sectional and ethics committee–approved study. A facility-based listing of services and human resources specific to geriatric patients was conducted in purposively sampled 27 tertiary government hospitals identified as geriatric centers and 16 health centers across all regions in the Philippines. We also reviewed the existing policies and guidelines related to HISs for OPs in the country.

Results

Based on the existing guidelines, multiple agencies were involved in the provision of services for OPs, with several records containing health information of OPs. However, there is no existing HIS specific for OPs in the country. Only 14 (52%) of the 27 hospitals and 4 (25%) of the 16 health centers conduct comprehensive geriatric assessment (CGA). All tertiary hospitals and health centers are able to maintain medical records of their patients, and almost all (26/27, 96%) hospitals and all (16/16, 100%) health centers have data on top causes of morbidity and mortality. Meanwhile, the presence of specific disease registries varied per hospitals and health centers. Challenges to HISs include the inability to update databases due to inadequately trained personnel, use of an offline facility–based HIS, an unstable internet connection, and technical issues and nonuniform reporting of categories for age group classification.

Conclusions

Current HISs for OPs are characterized by fragmentation, multiple sources, and inaccessibility. Barriers to achieving appropriate HISs for OPs include the inability to update HISs in hospitals and health centers and a lack of standardization by age group and disease classification. Thus, we recommend a 1-person, 1-record electronic medical record system for OPs and the disaggregation and analysis across demographic and socioeconomic parameters to inform policies and programs that address the complex needs of OPs. CGA as a required routine procedure for all OPs and its integration with the existing HISs in the country are also recommended.
A Casual Video Game With Psychological Well-being Concepts for Young Adolescents: Protocol for an Acceptability and Feasibility Study
Authors: Pine Russell , Mbinta James , Te Morenga Lisa , Fleming Theresa
Published: July 2021

Background

Many face-to-face and digital therapeutic supports are designed for adolescents experiencing high levels of psychological distress. However, promoting psychological well-being among adolescents is often neglected despite significant short-term and long-term benefits.

Objective

This research has 3 main objectives: (1) to assess the acceptability of Match Emoji, a casual video game with psychological well-being concepts among 13-15-year-old students in a New Zealand secondary school; (2) to identify the feasibility of the research process; and (3) to explore the preliminary well-being and therapeutic potential of Match Emoji.

Methods

Approximately 40 participants aged 13-15 years from a local secondary college in Wellington, New Zealand, will be invited to download and play Match Emoji 3-4 times a week for 5-15 minutes over a 2-week period. Participants will complete 4 assessments at baseline, postintervention, and 3 weeks later to assess psychological well-being and therapeutic changes. Statistical analysis will be used to synthesize data from interviews and triangulated with assessment changes and game analytics. This synthesis will help to assess the acceptability and feasibility of the Match Emoji.

Results

The key outputs from the project will include the acceptability, feasibility, and therapeutic potential of Match Emoji. It is anticipated that participants will have finished playing the recommended game play regimen by August 2021 with analysis of results completed by October 2021.

Conclusions

Data from the study are expected to inform future research on Match Emoji including a randomized controlled trial and further adjustments to the design and development of the game.

International Registered Report Identifier (IRRID)

PRR1-10.2196/31588
Longitudinal, Interdisciplinary Home Visits Versus Usual Care for Homebound People With Advanced Parkinson Disease: Protocol for a Controlled Trial
Authors: Fleisher Jori E , Hess Serena , Sennott Brianna J , Myrick Erica , Wallace Ellen Klostermann , Lee Jeanette , Sanghvi Maya , Woo Katheryn , Ouyang Bichun , Wilkinson Jayne R , Beck James , Johnson Tricia J , Hall Deborah A , Chodosh Joshua
Published: July 2021

Background

The current understanding of advanced Parkinson disease (PD) and its treatment is largely based on data from outpatient visits. The most advanced and disabled individuals with PD are disconnected from both care and research. A previous pilot study among older, multimorbid patients with advanced PD demonstrated the feasibility of interdisciplinary home visits to reach the target population, improve care quality, and potentially avoid institutionalization.

Objective

The aim of this study protocol is to investigate whether interdisciplinary home visits can prevent a decline in quality of life of patients with PD and prevent worsening of caregiver strain. The protocol also explores whether program costs are offset by savings in health care utilization and institutionalization compared with usual care.

Methods

In this single-center, controlled trial, 65 patient-caregiver dyads affected by advanced PD (Hoehn and Yahr stages 3-5 and homebound) are recruited to receive quarterly interdisciplinary home visits over 1 year. The 1-year intervention is delivered by a nurse and a research coordinator, who travel to the home, and it is supported by a movement disorder specialist and social worker (both present by video). Each dyad is compared with age-, sex-, and Hoehn and Yahr stage–matched control dyads drawn from US participants in the longitudinal Parkinson’s Outcome Project registry. The primary outcome measure is the change in patient quality of life between baseline and 1 year. Secondary outcome measures include changes in Hoehn and Yahr stage, caregiver strain, self-reported fall frequency, emergency room visits, hospital admissions, and time to institutionalization or death. Intervention costs and changes in health care utilization will be analyzed in a budget impact analysis to explore the potential for model adaptation and dissemination.

Results

The protocol was funded in September 2017 and approved by the Rush Institutional Review Board in October 2017. Recruitment began in May 2018 and closed in November 2019 with 65 patient-caregiver dyads enrolled. All study visits have been completed, and analysis is underway.

Conclusions

To our knowledge, this is the first controlled trial to investigate the effects of interdisciplinary home visits among homebound individuals with advanced PD and their caregivers. This study also establishes a unique cohort of patients from whom we can study the natural course of advanced PD, its treatments, and unmet needs.

Trial Registration

ClinicalTrials.gov NCT03189459; http://clinicaltrials.gov/ct2/show/NCT03189459.

International Registered Report Identifier (IRRID)

PRR1-10.2196/31690
Approaches for Implementing App-Based Digital Treatments for Drug Use Disorders Into Primary Care: A Qualitative, User-Centered Design Study of Patient Perspectives (Preprint)
Authors: Glass Joseph E , Matson Theresa E , Lim Catherine , Hartzler Andrea L , Kimbel Kilian , Lee Amy K , Beatty Tara , Parrish Rebecca , Caldeiro Ryan M , Garza McWethy Angela , Curran Geoffrey M , Bradley Katharine A
Published: July 2021

BACKGROUND

Digital interventions, such as websites and smartphone apps, can be effective in treating drug use disorders (DUDs). However, their implementation in primary care is hindered, in part, by a lack of knowledge on how patients might like these treatments delivered to them.

OBJECTIVE

This study aims to increase the understanding of how patients with DUDs prefer to receive app-based treatments to inform the implementation of these treatments in primary care.

METHODS

The methods of user-centered design were combined with qualitative research methods to inform the design of workflows for offering app-based treatments in primary care. Adult patients (n=14) with past-year cannabis, stimulant, or opioid use disorder from 5 primary care clinics of Kaiser Permanente Washington in the Seattle area participated in this study. Semistructured interviews were recorded, transcribed, and analyzed using qualitative template analysis. The coding scheme included deductive codes based on interview topics, which primarily focused on workflow design. Inductive codes emerged from the data.

RESULTS

Participants wanted to learn about apps during visits where drug use was discussed and felt that app-related conversations should be incorporated into the existing care whenever possible, as opposed to creating new health care visits to facilitate the use of the app. Nearly all participants preferred receiving clinician support for using apps over using them without support. They desired a trusting, supportive relationship with a clinician who could guide them as they used the app. Participants wanted follow-up support via phone calls or secure messaging because these modes of communication were perceived as a convenient and low burden (eg, no copays or appointment travel).

CONCLUSIONS

A user-centered implementation of treatment apps for DUDs in primary care will require health systems to design workflows that account for patients’ needs for structure, support in and outside of visits, and desire for convenience.
An Unstructured Supplementary Service Data System for Daily Tracking of Patient Samples and Diagnostic Results in a Diagnostic Network in Malawi: System Development and Field Trial (Preprint)
Authors: Killian Daniel , Gibson Emma , Kachule Mphatso , Palamountain Kara , Bangoh Joseph Bitilinyu , Deo Sarang , Jonasson Jonas Oddur
Published: July 2021

BACKGROUND

Diagnostics in many low- and middle-income countries are conducted through centralized laboratory networks. Samples are collected from patients at remote point-of-care health facilities, and diagnostic tests are performed at centralized laboratories. Sample transportation systems that deliver diagnostic samples and test results are crucial for timely diagnosis and treatment in such diagnostic networks. However, they often lack the timely and accurate data (eg, the quantity and location of samples prepared for collection) required for efficient operation.

OBJECTIVE

This study aims to demonstrate the feasibility, adoption, and accuracy of a distributed data collection system that leverages basic mobile phone technology to gather reports on the quantity and location of patient samples and test results prepared for delivery in the diagnostic network of Malawi.

METHODS

We designed a system that leverages unstructured supplementary service data (USSD) technology to enable health workers to submit daily reports describing the quantity of transportation-ready diagnostic samples and test results at specific health care facilities, free of charge with any mobile phone, and aggregate these data for sample transportation administrators. We then conducted a year-long field trial of this system in 51 health facilities serving 3 districts in Malawi. Between July 2019 and July 2020, the participants submitted daily reports containing the number of patient samples or test results designated for viral load, early infant diagnosis, and tuberculosis testing at each facility. We monitored daily participation and compared the submitted USSD reports with program data to assess system feasibility, adoption, and accuracy.

RESULTS

The participating facilities submitted 37,771 reports over the duration of the field trial. Daily facility participation increased from an average of 50% (26/51) in the first 2 weeks of the trial to approximately 80% (41/51) by the midpoint of the trial and remained at or above 80% (41/51) until the conclusion of the trial. On average, more than 80% of the reports submitted by a facility for a specific type of sample matched the actual number of patient samples collected from that facility by a courier.

CONCLUSIONS

Our findings suggest that a USSD-based system is a feasible, adoptable, and accurate solution to the challenges of untimely, inaccurate, or incomplete data in diagnostic networks. Certain design characteristics of our system, such as the use of USSD, and implementation characteristics, such as the supportive role of the field team, were necessary to ensure high participation and accuracy rates without any explicit financial incentives.
Attitudinal barriers hindering adoption of Telepsychiatry among mental healthcare professionals: Israel as a case-study (Preprint)
Authors: Magal Tamir , Negev Maya , Kaphzan Hanoch
Published: July 2021

BACKGROUND

Despite obvious and proven advantages for the use of telemedicine in psychiatry, mental healthcare professionals have shown deep-seated mistrust and suspicion of telepsychiatry, which hinders its widespread application.

OBJECTIVE

The current study aims to examine the attitudes of Israeli mental health professionals towards telepsychiatry; seeking to uncover the relationship with experience with telepsychiatry, and organizational affiliation.

METHODS

A qualitative study, including 27 in-depth interviews with Israeli mental-health professionals, representing a diverse analytical, geographical, and gendered cross-section of the local professional community. A thematic analysis revealed three major themes – economic efficiency, clinical quality, and the effects on the work-life balance of healthcare professionals. Individuals’ responses were furthermore compared against hierarchical position, organizational affiliation, and experience with telepsychiatry.

RESULTS

Participants were evenly divided, between supporters of telepsychiatry and those who oppose and object to its widespread usage in routine mental healthcare. This division manifested itself most clearly in their assessment of the clinical quality of telepsychiatry. However, it was also palpable in their assessment of its efficiency and its effects for healthcare professionals. Furthermore, the study also revealed a positive correlation between participants’ experience with telepsychiatry, and their support for its usage. However, this relationship seems to be mitigated by one’s employment and organizational affiliations. Employees of at least one Israeli Health Maintenance Organization exhibited a negative trendline, where more experience with telepsychiatry also meant stronger opposition for its utilization.

CONCLUSIONS

Attitudes of mental health professionals were found to be widely divergent and sharply dichotomized regarding different aspects of telepsychiatry, and its suitability for mental healthcare services. However, there was general consensus that telemedicine may not fulfil its promise of being a panacea to the problems of modern public medicine. At the same time, attitudes were related to hierarchical position, organizational affiliation and personal experience with telepsychiatry. Specifically, organizational affiliation influenced experience with and support for assimilation of telepsychiatry. The study also revealed the role of organizational leadership and culture in promoting or inhibiting the proliferation and adoption of innovative technologies and services in modern medicine.
The Effect of Zeolite Toward Ammonia (NH3) in Tilapia Rearing Media with Recirculation System
Authors: Hasibuan Saberina Rina , Syafriadiman Syafriadiman , Syahputra Muhammad Nandy
Published: July 2021

Culture of Tilapia (Oreochromis niloticus) with high stocking density and feeding can cause a decrease in water quality due to the accumulation of metabolic waste such as ammonia which is toxic for fish rearing. A zeolite filter is needed which can reduce ammonia levels until it is not harmful to fish survival. This research was conducted in February-April 2020 at the Aquaculture Environmental Quality Laboratory, Fisheries and Marine Faculty of Riau University. The purposed of this study was to determine the effect of using zeolite on Ammonia (NH3) and determine the appropriate dose for Tilapia (Oreochromis niloticus) rearing. The research method was a Completely Randomized Design (CRD) one factor with 4 levels of treatment (P0: Control without the use of filters, P1: Use of zeolite 5.68 g/L, P2: Use of zeolite 11.37 g/L, P3: Use of zeolite 17.05 g/L). The appropriate treatment for Tilapia rearing is P3 (Zeolite 17.05 g/L) with TAN value is 0.2616 mg/L, Ammonia 0.0018 mg/L, TAN reduction is 59%, and Survival Rate of fish is 88.88%. The value of water quality during the study were temperature 27-29 oC, pH 6.7-7.0, and DO 6.2-6.9 mg/L.
Erfahrungen und Ergebnisse aus der begleitenden Erhebung zum Pilot w-fFORTE Innovatorinnen
Authors:   FFG, Alber Charlotte , Dusl Laura , Ecker Brigitte , Pohoryles-Drexel Sabine
Published: July 2021

Mit w-fFORTE Innovatorinnen strebt das Bundesministerium für Digitalisierung und Wirtschaftsstandort (BMDW) an, Frauen in standortrelevanter Forschung und Innovation (F&I) gezielt zu unterstützen und sichtbar zu machen. Hochqualifizierte Frauen werden darin bestärkt, ihre Ideen zu entfalten, neue Netzwerk-Kontakte aufzubauen und zu mehr Gestaltungsspielräumen und beruflicher Weiterentwicklung zu gelangen. Die FFG hat dafür im Zeitraum 2018-2019 in enger Zusammenarbeit mit dem BMDW ein innovatives Leadership- & Empowerment-Programm entwickelt. Der erste Durchgang fand als Pilot von Juni 2020 bis April 2021 mit insgesamt 21 Innovatorinnen statt, die von einer Jury aus einer Vielzahl von Bewerberinnen ausgewählt wurden. Während der Pilot-Laufzeit wurde eine begleitende Erhebung durch WPZ Research durchgeführt. Ziel war es, die Wirksamkeit des Pilots zu prüfen und Evidenzen für eine mögliche Weiterführung der Aktivitäten zu erhalten.
Lysophospholipid (S1P) receptors in GtoPdb v.2021.2
Authors: Blaho Victoria , Chun Jerold , Jones Danielle , Jonnalagadda Deepa , Kihara Yasuyuki , Tan Valerie P.
Published: July 2021

Sphingosine 1-phosphate (S1P) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid receptors [89]) are activated by the endogenous lipid sphingosine 1-phosphate (S1P). Originally cloned as orphan members of the endothelial differentiation gene (edg) family [16, 112], the receptors are currently designated as S1P1R through S1P5R [69, 16, 112]. Their gene nomenclature has been codified as human S1PR1, S1PR2, etc. (HUGO Gene Nomenclature Committee, HGNC) and S1pr1, S1pr2, etc. for mice (Mouse Genome Informatics Database, MGI) to reflect species and receptor function. All S1P receptors have been knocked-out in mice constitutively and in some cases, conditionally. S1PRs, particularly S1P1, are expressed throughout all mammalian organ systems. Ligand delivery occurs via two known carriers (or "chaperones"): albumin and HDL-bound apolipoprotein M (ApoM), the latter of which elicits biased agonist signaling by S1P1 in multiple cell types [18, 49]. The five S1PRs, two chaperones, and active cellular metabolism have complicated analyses of receptor ligand binding in native systems. Signaling pathways and physiological roles have been characterized through radioligand binding in heterologous expression systems, targeted deletion of the different S1PRs, and most recently, mouse models that report in vivo S1P1R activation [94, 96]. A crystal structure of an S1P1-T4 fusion protein confirmed aspects of ligand binding, specificity, and receptor activation, determined previously through biochemical and genetic studies [65, 17]. fingolimod (FTY720), the first FDA-approved drug to target any of the lysophospholipid receptors, binds as a phosphorylated metabolite to four of the five S1PRs, and was the first oral therapy for multiple sclerosis (MS) [33]. siponimod and ozanimod that target S1P1 and S1P5 are also FDA approved for the treatment of various MS forms [16, 112]. The mechanisms of action of fingolimod and other S1PR-modulating drugs now in development include binding S1PRs in multiple organ systems, e.g., immune and nervous systems, although the precise nature of their receptor interactions requires clarification [129, 35, 59, 60].
Peningkatan penerimaan diri pasien skizofrenia melalui Rational Emotif Behavior Therapy
Authors: Putri Karindra Aldila
Published: July 2021

Delusions and irrational thoughts often appear in schizophrenic patients. Can those negative thoughts be reduced to them? Rational Emotive Behavior Therapy (REBT) is designed to help overcome the problems of negative thinking in schizophrenia. The assessment was carried out using interviews, observation and several psychological tests with the results of the dominance of negative feelings and low self-acceptance. The intervention aims to break irrational beliefs and increase self-acceptance through REBT techniques. The results of the intervention show that the client can see things from a different perspective in order to generate new, more rational thoughts so as to increase the client’s acceptance of himself, others, and the environment.
PROPERTIES OF A COMPLEX DYNAMIC SYSTEM IN THE STRUCTURE OF WORDPLAY AND ITS TRANSLATION
Authors:   ZAREMA M. SAFINA Bashkir State University, SAFINA ZAREMA M. , TERENTYEV OLEG S. ,   OLEG S. TERENTYEV Bashkir State University
Published: July 2021

The article studies structural characteristics of wordplay and ways of its translation from English into Russian. The research is a case study of wordplay translation in the lyrics of еру American rap artist Eminem. We argue that the theory of complex dynamic systems helps reveal the many aspects of wordplay. The vertical and horizontal axes of wordplay, the peculiarities of their use in the artist’s verses, as well as the difficulties of translating wordplay were considered. Any difficulties and differences that result from the translation process may be overcome if the language is viewed as a complex fractal system. It is concluded that the modern system approach provides a completely different conceptual framework for the linguist. The properties of a language as a dynamic system should be taken into account in wordplay investigation and wordplay translation to ensure adequate interpretation of the ideas meant by the author.
FRAME ANALYSIS OF THE NOTION «CONTROL» IN GERMAN FOREIGN LANGUAGE TEACHING DISCOURSE
Authors:   ANASTASIA A. FILIPPOVA  Perm State University, FILIPPOVA ANASTASIA A.
Published: July 2021

The article discusses the terminological competence of students in foreign language teaching. Terminological competence means knowledge of terms of the subject area and ability to apply them in professional activity according to the set tasks. A frame analysis of terms is proposed as one of the methods that contribute to faster and better formation of terminology competence. Frame analysis includes the compilation of a frame and a detailed description of its slots. There is an example of a frame analysis of the concept of «control» in German in foreign language teaching discourse. As a result of the analysis of this discourse, a two-level frame was compiled, whose slots of the first order are «management», «diagnostics», «examination», «teaching». Second-order slots include «teacher» and «student» slots that relate to the first-level slot «management». It is concluded that slots of the frame set projection to functions of control in foreign language teaching discourse. Frame analysis is seen as a method to reveal the semantic potential of terms and to better understand their correlation in the term system.
CREATIVE NAMING OF NIZHNY NOVGOROD PUBLIC CATERING ESTABLISHMENTS: GRAPHIC ASPECT
Authors:   VLADISLAV E. ZAMALDINOV Nizhny Novgorod Academy of the Ministry of internal Affairs of Russia, ZAMALDINOV VLADISLAV E.
Published: July 2021

The purpose of the research is to analyze the creative naming of Nizhny Novgorod public catering establishments (restaurants, cafes, bars, burgers, coffee shops, pizzerias) from the point of view of graphics. The source of the material for the study was the personal card index of ergonyms. During the course of study, the following research methods were applied: general scientific method, particularly generalization, interpretation and classification of material, word-formation analysis and pragmatic analysis. It was discovered that innovations created by means of graphic hybridization act as a productive way of influencing the consumer. Ergonyms-innovations are easy to remember, have expressiveness, form positive associations, identify the institution. The analysis of the material showed that the most productive patterns of graphic hybridization were monographixation (33%), polygraphixation (47%) and tographixation (18%). It is noted that for a more powerful impact on the recipient, the nominators combine different paterns in one ergonym (2%).
Stim: a fast stabilizer circuit simulator
Authors: Gidney Craig
Published: July 2021

This paper presents “Stim", a fast simulator for quantum stabilizer circuits. The paper explains how Stim works and compares it to existing tools. With no foreknowledge, Stim can analyze a distance 100 surface code circuit (20 thousand qubits, 8 million gates, 1 million measurements) in 15 seconds and then begin sampling full circuit shots at a rate of 1 kHz. Stim uses a stabilizer tableau representation, similar to Aaronson and Gottesman's CHP simulator, but with three main improvements. First, Stim improves the asymptotic complexity of deterministic measurement from quadratic to linear by tracking the inverse of the circuit's stabilizer tableau. Second, Stim improves the constant factors of the algorithm by using a cache-friendly data layout and 256 bit wide SIMD instructions. Third, Stim only uses expensive stabilizer tableau simulation to create an initial reference sample. Further samples are collected in bulk by using that sample as a reference for batches of Pauli frames propagating through the circuit.
“Just Shave It Off”
Authors: Jankowski Glen , Sherwin Michael , Deighton-Smith Nova , Bell Beth T.
Published: July 2021

Introduction

Head hair comprises a critical part of the male appearance ideal, which itself is a crucial signifier of a man’s masculinity. However, difficulties in recruitment have meant that research has not yet fully explored how men construct the loss of head hair (baldness), perhaps because it is considered “feminine” to disclose body dissatisfaction experiences to a researcher or other people.

Methods and Design

Online forums provide an opportunity for the anonymous discussion of body dissatisfaction that may overcome this obstacle. The first 260 forums posts from the two most popular baldness forums were thematically analysed.

Ethics Statement

Institutional ethics approval was granted.

Results and Discussion

We identified three themes titled: (1) Baldness is an ugly and demasculinising condition, (2) Baldness is stigmatised by a superficial society and superficial women and (3) Resistance to baldness despair. Our findings show baldness distress, and stigma exist though so does resistance, which can be comforting to men experiencing baldness or any form of body dissatisfaction.

Conclusion and Implications

Online forums are a salient resource to enhance our understanding of men’s balding concerns and disclosure barriers. Independent, professional and effective baldness support that unpacks baldness masculinised and medicalised framing is recommended.
Analisis faktor-faktor yang mempengaruhi pertumbuhan ekonomi di Kabupaten Sarolangun
Authors: Rosminah Rosminah , Nurjanah Rahma , Umiyati Etik
Published: July 2021

Investment (PMDN) and government expenditures have on economic growth in Sarolangun Regency. The type of data used is secondary data in the form of time series data for 2000-2017, in the form of data on economic growth, the number of workers, PMDN, and government spending. The analytical method used in this study is multiple linear regression or Ordinary Least Square (OLS). Based on the analysis results indicate that the workforce has a positive and significant effect on economic growth. PMDN has a positive and significant effect on economic growth. Likewise, government spending has a positive and significant effect on economic growth.
Keywords: Economic growth, Labor, Domestic investment (PMDN), Goverment expenditure.
Pengaruh FED rate, inflasi, dan indeks NIKKEI 225 terhadap IHSG di Indonesia (2016-2017)
Authors: Joventus Joventus Partogi Silaen , Haryadi Haryadi , Emilia Emilia
Published: July 2021

This study aims to analyze the influence and look at the Fed Rate, Inflation in Indonesia, and the NIKKEI 225 Index on the Composite Stock Price Index (JCI). The data used in this study is secondary data obtained from Bank Indonesia, Investing.com, library sources, journals, and other scientific articles. The analytical method used in this study is the multiple linear regression analysis method using the Ordinary Least Square (OLS) method. Data is processed using software using monthly data with the research period from January 2016-December 2017 sourced from the internet, scientific journals, and books. The results of this study indicate that partially the FED Rate variable has a negative effect on the JCI, Inflation has a negative effect on the JCI, and the NIKKEI 225 Index has no effect on the NIKKEI 225 Index. Meanwhile, simultaneously all variables affect the JCI.
Keywords: Fed Rate, Inflation, NIKKEI 225 Index, IDX
Hubungan kausalitas ekspor batubara dengan pertumbuhan ekonomi Provinsi Jambi
Authors: Wahyuni Iis Puji , Amir Amri , Nurjanah Rahma
Published: July 2021

In this study aims to (1) know the development of economic growth and know the development of coal exports (2) find out the causality of coal exports with the economic growth of Jambi Province. The data used in this study are secondary data sourced from the Central Statistics Agency (BPS) of Jambi Province. To answer these objectives, this study uses a type of quantitative descriptive research with an analysis model for the first and second problems using simple regression analysis and granger causality test. The results of the study show that (1) the average development of economic growth in Jambi Province in 2004-2018 was 6.15 percent; (2) the average development of coal exports is 149.64 percent, and (3) partially coal exports do not have a causal relationship to the economic growth of Jambi Province
 Keywords: Economic growth, Coal exports
Pengaruh penanaman modal dalam Negeri, penanaman modal asing dan ekspor terhadap PDRB Provinsi Jambi Periode 2000- 2016
Authors: Tarmizi Tarmizi , Hodijah Siti , Rosmeli Rosmeli
Published: July 2021

This study aims to analyze the development of GRDP, domestic investment, foreign investment, and exports in Jambi Province for the period 2000-2016, as well as to study the effect of domestic investment, foreign investment, and exports on the growth of GRDP of Jambi Province in the period 2000-2016. 2016. This research uses descriptive and quantitative analysis methods. The descriptive analysis method is used to analyze the development of each research variable, namely domestic investment, foreign investment, and exports. Quantitative analysis methods are used to analyze the effect of domestic investment, foreign investment, and exports on the growth of GRDP in Jambi province for the period 2000-2016. Based on the study results, the Jambi Province GRDP growth for the 2000-2016 period was 7.21 percent, domestic investment growth was 11.64 percent, foreign investment was 18.69 percent, and export development was 17.83 percent. And during the period 2000-2016, domestic investment, foreign investment, and exports had a significant effect on GRDP growth in Jambi Province.
Keywords: Domestic investment, Foreign investment, Exports, PDRB Growth
Liberdade é Trabalho e Cansaço: contribuições para o debate sobre interseccionalidade
Authors: Souzas Raquel , Marinho Olivia Ferraz Pereira , De Jesus Carliene Sousa , Santos Amalia Nascimento do Sacramento
Published: July 2021

O presente artigo busca articular reflexões a partir da teoria da interseccionalidade. Nesse campo, a questão da liberdade é um ponto importante e é antípoda do racismo. A forma pela qual as mulheres negras afirmam a liberdade, individual ou coletivamente, produz resultados políticos e sociais. Neste artigo buscamos analisar a percepção da liberdade no cotidiano. Foram entrevistadas mulheres negras de diferentes níveis de escolaridade, em idade reprodutiva, residentes do sudoeste baiano. A liberdade se apresenta como uma possibilidade que advém de conquistas econômicas e sociais. É, nesse sentido, resultante de lutas coletivas e sociais. O racismo é, então, uma barreira importante a ser considerada a partir da teoria da interseccionalidade. A estruturação de sentidos e significados construídos nas narrativas do cotidiano pode auxiliar na compreensão das condições sociais e de vida das mulheres negras e orientar hipóteses de pesquisa e de ação política.
Santa Librada, de los partos difíciles a la Independencia de Cundinamarca
Authors: Martinez Martin Abel Fernando , Otalora Cascante Andres Ricardo
Published: July 2021

Este artículo aborda la leyenda y la historia de santa Librada y su relación taumatúrgica con los partos difíciles, la esterilidad y los problemas conyugales; la introducción de su culto por el obispo-virrey Ladrón de Guevara en el siglo XVIII en Panamá, Quito y Lima y su llegada al convento-hospital de San Juan de Dios de Santafé. La relación de la fiesta de la santa con el día de la Independencia originó una particular simbiosis de este símbolo, primero taumatúrgico y luego político, que hizo parte de la fiesta nacional de Colombia hasta los años sesenta del siglo XX.