bluuebunny/crossref_metadata_2025 huggingface dataset:
Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer
Authors: Wu Qi-Long , Fang Xiao-Ting , Wan Xin-Xin , Ding Qing-Yong , Zhang Yan-Jun , Ji Ling , Lou Yong-Liang , Li Xiang
Published: April 2024

BACKGROUND

Colorectal cancer (CRC) ranks among the most prevalent malignant tumors globally. Recent reports suggest that Fusobacterium nucleatum (F. nucleatum ) contributes to the initiation, progression, and prognosis of CRC. Butyrate, a short-chain fatty acid derived from the bacterial fermentation of soluble dietary fiber, is known to inhibit various cancers. This study is designed to explore whether F. nucleatum influences the onset and progression of CRC by impacting the intestinal metabolite butyric acid.

AIM

To investigate the mechanism by which F. nucleatum affects CRC occurrence and development.

METHODS

Alterations in the gut microbiota of BALB/c mice were observed following the oral administration of F. nucleatum . Additionally, DLD-1 and HCT116 cell lines were exposed to sodium butyrate (NaB) and F. nucleatum in vitro to examine the effects on proliferative proteins and mitochondrial function.

RESULTS

Our research indicates that the prevalence of F. nucleatum in fecal samples from CRC patients is significantly greater than in healthy counterparts, while the prevalence of butyrate-producing bacteria is notably lower. In mice colonized with F. nucleatum , the population of butyrate-producing bacteria decreased, resulting in altered levels of butyric acid, a key intestinal metabolite of butyrate. Exposure to NaB can impair mitochondrial morphology and diminish mitochondrial membrane potential in DLD-1 and HCT116 CRC cells. Consequently, this leads to modulated production of adenosine triphosphate and reactive oxygen species, thereby inhibiting cancer cell proliferation. Additionally, NaB triggers the adenosine monophosphate-activated protein kinase (AMPK) signaling pathway, blocks the cell cycle in HCT116 and DLD-1 cells, and curtails the proliferation of CRC cells. The combined presence of F. nucleatum and NaB attenuated the effects of the latter. By employing small interfering RNA to suppress AMPK, it was demonstrated that AMPK is essential for NaB’s inhibition of CRC cell proliferation.

CONCLUSION

F. nucleatum can promote cancer progression through its inhibitory effect on butyric acid, via the AMPK signaling pathway.
Measuring the variability of personality traits with interval responses: Psychometric properties of the dual-range slider response format
Authors: Kloft Matthias , Snijder Jean-Paul , Heck Daniel W.
Published: April 2024

Measuring the variability in persons’ behaviors and experiences using ecological momentary assessment is time-consuming and costly. We investigate whether interval responses provided through a dual-range slider (DRS) response format can be used as a simple and efficient alternative: Respondents indicate variability in their behavior in a retrospective rating by choosing a lower and an upper bound on a continuous, bounded scale. We investigate the psychometric properties of this response format as a prerequisite for further validation. First, we assess the test–retest reliability of factor-score estimates for the width of DRS intervals. Second, we test whether factor-score estimates of the visual analog scale (VAS) and the location of DRS intervals show convergent validity. Third, we investigate whether factor-score estimates for the DRS are uncorrelated between different personality scales. We present a longitudinal multitrait-multimethod study using two personality scales (Extraversion, Conscientiousness) and two response formats (VAS, DRS) at two measurement occasions (6–8 weeks apart) for which we estimate factor-score correlations in a joint item response theory model. The test–retest reliability of the width of DRS intervals was high ($$\hat{\rho } \ge .73$$

ρ
^

≥
.
73

). Also, convergent validity between location scores of VAS and DRS was high ($$\hat{\rho } \ge .88$$

ρ
^

≥
.
88

). Conversely, discriminant validity of the width of DRS intervals between Extraversion and Conscientiousness was poor ($$\hat{\rho } \ge .94$$

ρ
^

≥
.
94

). In conclusion, the DRS seems to be a reliable response format that could be used to measure the central tendency of a trait equivalently to the VAS. However, it might not be well suited for measuring intra-individual variability in personality traits.
Synthesis and characterization of water-soluble C60–peptide conjugates
Authors: Ma Yue , Persi Lorenzo , Yamakoshi Yoko
Published: April 2024

With the aim of developing biocompatible and water-soluble C60 derivatives, three types of C60–peptide conjugates consisting of hydrophilic oligopeptide anchors (oligo-Lys, oligo-Glu, and oligo-Arg) were synthesized. A previously reported Prato reaction adduct of a biscarboxylic acid-substituted C60 derivative was subjected to a solid phase synthesis for amide formation with N-terminal amines of peptides on resin to successfully provide C60–peptide conjugates with one C60 and two peptide anchors as water-soluble moieties. Among three C60–peptide conjugates prepared, C60–oligo-Lys was soluble in water at neutral pH, and C60–oligo-Glu was soluble in buffer with a higher pH value, but C60–oligo-Arg was insoluble in water and most other solvents. C60–oligo-Lys and C60–oligo-Glu were characterized by 1H and 13C NMR. Photoinduced 1O2 generation was observed in the most soluble C60–oligo-Lys conjugate under visible light irradiation (527 nm) to show the potential of this highly water-soluble molecule in biological systems, for example, as a photosensitizer in photodynamic therapy.
The Effect of Quality of Service, Purchase Interest, Brand Trust on Purchase Decision
Authors: Parasari Nyoman Sri Manik , Pranajaya I Kadek Widi , Maheswari A.A. Istri Agung
Published: April 2024

Concert organizers in Bali are increasing almost every year, this project requires consideration of many things that can affect the decision to buy tickets and from this the organizer relies on services such as event organizers to help run the project smoothly. Balinese entertainment and cultural performances attract the attention of tourists and increase the resources of local communities, so that performances and entertainment in Bali are increasingly prominent in the world of arts and are able to compete in their class. The purpose of this study is to analyze service quality, purchase interest, and brand trust on purchasing decisions for Joyland Festival concert tickets. This research method uses purposive sampling with a sample of 126 respondents with predetermined characteristics and this research data collection method is collected through questionnaires, using SmartPLS 4.0 analysis techniques. The results of this study indicate that purchase intention, brand trust, and service quality influence purchasing decisions. Due to adding factors that influence purchasing choices, it is hoped that future researchers can expand the scope of their research.
Graphene Intercalated Multifunctional Polymer Networks as Acoustic Absorbers for Underwater Applications
Authors: Anna Davida Deepthi , Pacheeri Ananthakrishnan , Mampulliyalil Farsana , K V Neenu , P. Dhanyasree , Sabura Begum P. M. , Raghavan Prasanth , Raghavan Prasanth
Published: April 2024

Multifunctional polymer networks fortified with the power of graphene and its derivatives as nano-inclusions have excellent sound absorption efficiency in broad frequency range, high loss factor, and matching impedance with that of water along with exceptional thermal, mechanical, and tribological properties are found to be the pre-eminent material for the underwater acoustic applications, particularly for the military tactics. To develop a stealthy underwater acoustic material, various factors need to be carefully considered, including matching acoustic impedance, glass transition temperature, loss factor, tan δ value, compression set and other mechanical properties, thermal stability, adhesion, and other tribological properties, which is briefly summarized in this review. Strategical development of hybrid nano-inclusions, viscoelastic polymer networks, nanocomposites as well as various interpenetrating polymer networks (IPNs), assiduous synthesis and surface modification of graphene are pivotal key approaches that need to be appraised. Simulation studies focusing on various potential models need to be developed for the feasibility studies and designing of the underwater acoustic material.
ВЛИЯНИЕ СИСТЕМЫ УДОБРЕНИЙ НА БИОМЕТРИЧЕСКИЕ ПОКАЗАТЕЛИ И УРОЖАЙНОСТЬ КАРТОФЕЛЯ В УСЛОВИЯХ ЮГО-ВОСТОКА КАЗАХСТАНА
Authors: Алимханов Ербол , Айтбаев Темиржан , Айтбаева Акбопе
Published: April 2024

В статье представлены результаты исследований влияния удобрений на биометрические показатели и урожайность картофеля. В полевых опытах с зарубежными сортами картофеля и местным сортом-стандартом Тянь-Шанский установлено, что внесение удобрений в почву под картофель способствует увеличению высоты растения, количества стеблей и листьев, а также количества клубней на 1 куст.

Наиболее высокие показатели габитуса растений картофеля были отмечены на вариантах опыта с внесением высоких норм минеральных удобрений (N225P135K180) и совместного внесения органических и минеральных удобрений (N190P110K150 + навоз, 40 т/га). Так, высота растения на этих вариантах составила 67-82 см, количество стеблей - 5,3-6,1 штук, количество листьев - 116-145 штук, количество клубней - 11,6-14,7 штук на 1 куст.

Формирование мощно развитой биомассы картофельных растений способствовало получению более высоких урожаев клубней по сравнению с контролем (без удобрений). В среднем за 2 года исследований урожайность клубней картофеля на вариантах с внесением удобрений составила 26,0-38,4 т/га, что выше контроля на 39,46-66,53%.

Среди сортов картофеля по продуктивности наиболее отзывчивыми на удобрения были сорта Аладин и Инноватор. Урожайность этих сортов на вариантах с внесением удобрений составила 33,5-40,8 т/га и 31,8-38,4 т/га соответственно, что выше контроля на 54,69-66,53% и 37,07-65,52%.

Таким образом, результаты исследований свидетельствуют о том, что внесение удобрений в почву под картофель является эффективным способом повышения его продуктивности. При этом наиболее эффективны высокие нормы минеральных удобрений (N225P135K180) и совместное внесение органических и минеральных удобрений (N190P110K150 + навоз, 40 т/га).
ИСХОДНЫЙ МАТЕРИАЛ ДЛЯ СЕЛЕКЦИИ ОЗИМОЙ ПШЕНИЦЫ НА УСТОЙЧИВОСТЬ К ЖЕЛТОЙ РЖАВЧИНЕ (PUCCINIA STRIIFORMIS F. SP. TRITICI)
Authors: Дубекова Салтанат
Published: April 2024

Обеспечение продовольственной безопасности ориентирована на высокую урожайность, устойчивость к патогенам и абиотическим стрессам пшеницы. Селекция на устойчивость к болезням является важным направлением программ селекции растений, поскольку выводимые  сорта должны соответствовать высокой продуктивности, устойчивости к болезням и другим хозяйственно-ценным характеристикам для  конечного использования. На юго-востоке Казахстана среди болезней озимой пшеницы одним из наиболее вредоносных возбудителей является желтая ржавчина (Puccinia striiformis f. sp. tritici). Большинство возделываемых сортов пшеницы восприимчивы к возбудителю, поэтому постоянный контроль, изучение и создание новых исходных форм для селекции на устойчивость к этой опасной болезни являются острой необходимостью. Возделывание устойчивых сортов являются наиболее эффективным и экологически безопасным способом снижения потерь урожая.
С целью поиска источников устойчивости озимой пшеницы, в условиях искусственно-инфекционного фона, нами проведены селекционно-иммунологические исследования, на экспериментальной базе Казахского научно-исследовательского института земледелия и растениеводства (N43,238193°  E76,696753°). В настоящей статье представлены результаты фенотипических отборов резистентных форм в гибридных популяциях, полученные путем внутривидовых скрещиваний озимой пшеницы, их иммунологических особенностей к P. striiformis. Сочетание продуктивности с признаком устойчивости является определяющим фактором для успешного создания новых селекционных линий и ускоренного выведения сортов. Созданный исходный материал  может стать перспективным донором устойчивости к патогену для зерносеющих регионов.
ANALISIS KEPUASAN ORANG TUA DAN SISWA TERHADAP KUALITAS SARANA PENDIDIKAN DI SEKOLAH DASAR
Authors: Herman Nessa Mandani , Kaharuddin  , Ashar
Published: April 2024

Sekolah memiliki peran yang sangat penting dalam mencerdaskan kehidupan bangsa, sebagaimana telah tercantum dalam isi pembukaan UUD 1945 alinea IV yang menengaskan bahwa salah satu tujuan nasional bangsa Indonesia adalah mencerdaskan kehidupan bangsa. Penelitian ini bertujuan untuk mengetahui kepuasan orang tua dan siswa terhadap kualitas layanan pendidikan di SDI Parangkantisang kabupaten Gowa. Melalui penelitian ini diharapkan dapat mengetahui presepsi masyarakat, yaitu orang tua dan siswa terhadap layanan pendidikan. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif. Data hasil wawancara dianalisis secara deskriptif. Tingkat kepuasan orang tua dan siswa terhadap layanan pendidikan telah ditetapkan melalui hasil uji P (persentase). Hasil penelitian menunjukkan bahwa pada aspek Fasilitas tingkat kepuasan orang tua sebanyak 16%. Sedangkan pada aspek Proses Pembelajaran tingkat kepuasan siswa sebanyak 67%. Berdasarkan hasil penelitian yang telah dilakukan maka dapat disimpulkan bahwa terdapat perbedaan kepuasan kualitas pendidikan di SDI Parangkantisang pada masing-masing aspek yang dilihat dari dimensi: Fasilitas dan Proses Pembelajaran.
Sensor Based Air Pollutants Monitoring Using Unmanned Aerial Vehicle in Raipur City
Authors:   Civil Engineering Department, National Institute of Technology Raipur, Raipur, Chhattisgarh 492010, India, Lambey V. , Prasad A. D.
Published: April 2024

Sensor based air quality monitoring systems has an ability to provide real-time data with higher resolution. In the current study, small and portable sensor-based air quality monitoring system coupled with an unmanned aerial vehicle (UAV) platform has been used. Air pollutants such as particulate matter (PM10 and PM2.5), nitrogen dioxide (NO2), carbon monoxide (CO), and sulphur dioxide (SO2) are vertically monitored at eight different locations spread across four zones (i.e., industrial, transportation, residential, and public-place zone) in Raipur city. Vertical variation of pollutants at 5, 10, 15, and 20 m from ground level are monitored and analysed. Data has been analysed for the above five pollution causing parameters and it is observed that there is decreasing trend in the concentration has been observed to be winter > post-monsoon > monsoon season as reported in the previous studies for Raipur city. This type of monitoring system is cost effective as it requires UAV, sensors, mobile, and less skilled person for operation when compared to above mentioned monitoring systems in India. There are certain limitations of the study which includes less flying endurance of the UAV used with additional payload, observation of air pollutant concentration at lower altitude, and restrictions imposed on flying UAV at any location by the local authority due to COVID-19.
Assessment of Output Radiation Density of Cell Phone for Epidemiological Studies: A Pilot Study in Navi Mumbai
Authors:   MGM Institute of Health Sciences, MGM Campus, Kamothe, Navi Mumbai 410209, India, Indra V. S. , Maninder S. S. , BageSree S. ,   Department of Pediatrics, MGM Hospital, Navi Mumbai 410209, India, Revathi R.
Published: April 2024

In this research, the cell phone radiation output density of 167 different cell phone users has been systematically measured across various scenarios: (i) when no multimedia services were activated, (ii) when all multimedia services were activated (such as WhatsApp, Messenger, Viber, Skype, etc.), (iii) during calls without multimedia services, and (iv) during calls with all multimedia services activated. Through rigorous statistical analysis, the means for each of these four categories were computed. A notable finding is that the radiation output density from cell phones is at its highest during calls with all multimedia services activated (means 11.87 mW/m2 for 167 cell phones), whereas during calls with no multimedia services active, mean values are found 7.743 mW/m2. To establish a correlation between the quality of the signal received from the cell phone tower and the radiated power from the cell phone during calls, the output radiation from cell phones was also assessed using the Trifield Electromagnetic field (EMF) meter model (TF2) at different signal quality levels emitted by the towers. These signal quality levels were quantified by measuring Reference Signal Received Power (RSRP), Reference Signal Received Quality (RSRQ), and Received Signal Signal-to-Interference-plus-Noise Ratio (RSSINR). It was observed that the cell phone's radiated power was at its lowest (means 9.428 mW/m2 for 41 cell phones) when the received signal quality was excellent (RSRP: –70.84 dBm; RSRQ: –12.06 Db; RSSINR: 12.6 dB). Conversely, in areas with the worst received signal quality (RSRP: –82.86 dBm; RSRQ: –17.034 dB; RSSINR: 8.1774 dB), the output radiated power density from cell phones during calls (all multimedia services activated) was recorded at its highest (means 18.336 mW/m2 for 56 cell phones). Furthermore, the study revealed an inverse correlation between the radiated output power density of cell phones (167) and the quality of the received signal (RSRPr: –0.18456; RSRQr: –0.35026; RSSINRr: –0.6448). This implies that the cell phone's radiated power density is directly influenced by the quality of the received signal from cell phone tower (specifically, its electromagnetic field strength) and the activation of various multimedia services. These findings contribute to improving the indicators of radiofrequency (RF) exposure for use in epidemiological studies. The results highlight that output power density of cell phone increases as the signal level from the cell phone tower decreases. Thus, we can affirm that a low-quality cell phone tower signal during calls leads to increased output radiation of cell phone, consequently resulting in a higher incidence of epidemiological problems.
Policy Measures, Practices and Challenges of Waste-to-Energy: Perspectives from Nigeria and Nepal
Authors:   Department of Sustainable Engineering, Teri School of Advanced Studies, New Delhi 110070, India, Khanal A. , Giri S. , Oyebode O. J. , Omijeh J. E. , Khanal A. ,   Global Research Institute and Training Center (GRIT), Kathmandu 44600, Nepal,   Civil and Environmental Engineering Department, Afe Babalola University, Ado-Ekiti MD 20770, Nigeria,   Department of Forestry & Wildlife Management, Modibbo Adama University of Technology, Yola P.M.B. 2076, Nigeria,   Department of Civil Engineering, Tribhuvan University, Kathmandu 46000, Nepal
Published: April 2024

There are environmental and health concerns associated with some waste-to-energy (WtE) technologies, such as incineration, which emit pollutants that can harm the environment and public health. Furthermore, there is limited research on the sustainability and feasibility of WtE. This study provides a comparative analysis of waste management practices in Nigeria and Nepal and highlights the challenges and potential for implementing WtE plants. A comprehensive literature review was conducted, and data were gathered from online sources for analysis. The findings of this study suggest that both countries face significant challenges in managing solid waste, including inadequate infrastructure, lack of awareness among policymakers, and limited resources for managing waste. However, there is potential for implementing WtE technologies as a sustainable solution for managing solid waste in these regions. The challenges associateed with WtE technology, including the high capital cost of establishing facilities and environmental and health concerns, must be addressed to fully realize the benefits of this technology.
Bell Instability–mediated Diffusive Shock Acceleration at Supernova Blast Wave Shock Propagating in the Interstellar Medium
Authors: Inoue Tsuyoshi , Marcowith Alexandre , Giacinti Gwenael
Published: April 2024

Supernova blast wave shock is a very important site of cosmic-ray acceleration. However, the detailed physical process of acceleration, in particular, nonlinear interplay between cosmic-ray streaming and magnetic field amplification, has not been studied under a realistic environment. In this paper, using a unique and novel numerical method, we study cosmic-ray acceleration at supernova blast wave shock propagating in the interstellar medium with well-resolved magnetic field amplification by nonresonant hybrid instability (or Bell instability). We find that the magnetic field is mildly amplified under typical interstellar medium conditions that leads to maximum cosmic-ray energy ≃30 TeV for supernova remnants with age ≃1000 yr consistent with gamma-ray observations. The strength of the amplified magnetic field does not reach the so-called saturation level because the cosmic-ray electric current toward the shock upstream has a finite spatial extent, by which Bell instability cannot experience many e-folding times.
XMM–NuSTAR Observation and Multiwavelength Spectral Energy Distribution Modeling of Blazar 4FGL J1520.8–0348
Authors: Rajguru Garima , Marcotulli L. , Ajello M. , Tramacere A.
Published: April 2024

Active galactic nuclei (AGNs) can power relativistic jets, which are called blazars when pointed close to our line of sight. Depending on the presence or absence of emission lines in their optical spectra, blazars are categorized into flat spectrum radio quasars (FSRQs) or BL Lacertae (BL Lac) objects. According to the “blazar sequence,” as synchrotron peak frequency (

ν

pk

sy

) shifts to higher energies, the synchrotron peak luminosity decreases. This means that BL Lac objects as luminous as FSRQs, and with synchrotron peak frequencies

ν

pk

sy

>

10

15

Hz, should not exist. Detected as a high-synchrotron peak (HSP;

ν

pk

sy

>

10

15

Hz) BL Lac object, 4FGL J1520.8-0348 shows high γ-ray luminosity (L

γ
> 1046 erg s−1), being at a high redshift of z = 1.46. Since it is an outlier in the “blazar sequence,” the process of its jet acceleration and power may be different from bona fide BL Lac objects. In this work, we constrain its spectral energy distribution (SED) by modeling the multiwavelength data from infrared to γ-ray regime. Simultaneous X-ray data were obtained from X-ray Multi-Mirror Mission and Nuclear Spectroscopic Telescope Array to constrain the synchrotron emission and underlying electron distribution. On undertaking the SED modeling of the source, including the effect of extragalactic background light, we conclude that the source is more likely to be a “blue FSRQ” or “masquerading BL Lac” where the BL Lac object is actually an FSRQ in disguise.
Description of a new marine flatworm of Prosthiostomum (Platyhelminthes, Polycladida, Prosthiostomidae) from the South China Sea
Authors: Liu Hai-Long , Lin Da-Hao , Wang An-Tai , Hu Zhang-Li , Zhang Yu
Published: April 2024

A new species of the polyclad genus Prosthiostomum is described from the intertidal zone of the South China Sea, Huidong, China, based on morphological and molecular analyses. Prosthiostomum huidongensesp. nov. is characterized by i) few marginal eyes scattered between the marginal band and the cerebral eyes; ii) sucker located at two-thirds of the body length, being removed from the female gonopore by twice the distance between the male and female gonopores; iii) shallow male atrium with slightly ruffled inner wall, positioned approximately perpendicular to the body wall. Molecular phylogenetic analyses based on 28S rDNA sequence showed that the new species was nested in a clade composed of Prosthiostomum species. The uncorrected p-distance of COI between P. huidongensesp. nov. and other Prosthiostomum species ranged from 20.3 to 24.3%, and the high genetic divergence further supports P. huidongense as a new species.
« Créer une existence de l’Autre » : essai de pédagogie akermanienne
Authors: Jacomino Baptiste , Jacomino Baptiste
Published: April 2024

Dans un entretien qu’elle donne en 2000, Chantal Akerman nomme le cœur de son projet artistique en quelques mots : « créer une existence de l’Autre ». Il s’agit de réveiller le spectateur de l’idolâtrie, qui sans cesse menace de l’avaler, en lui offrant un espace où habiter et exister. Les gestes artistiques par lesquels la cinéaste met en œuvre cette intention peuvent inspirer des gestes pédagogiques adaptés à une époque où les élèves sont sans cesse exposés à la menace d’être avalés par les idoles, les images, les forçages et les dominations.
« J’ai honte donc je suis » : une lecture des Carnets du sous-sol de Fédor Dostoïevski
Authors: Galkina Maria
Published: April 2024

Et si c’était la honte, et non le doute, qui exprimait la première certitude de notre existence ? Le présent article explore cette hypothèse à partir d’une lecture originale des Carnets du sous-sol de Fédor Dostoïevski en cherchant à saisir et à mettre en exergue la conscience du sujet de la honte. Ce personnage dostoïevskien, en effet, prend conscience de soi à travers le vécu de sa propre défaite, tel qu’il s’exprime dans ce sentiment. En montrant d’abord que le moi du sujet de la honte se structure comme un désaccord intérieur, l’article associe ensuite la honte à l’impuissance à échapper à soi-même. La présence irrémissible à soi, telle qu’elle se découvre dans l’exposition à l’autre est définie comme le levier dialectique de cette prise de conscience de l’existence que déclenche la honte.
Transgressions
Authors: Kaës René
Published: April 2024

La transgression qu’implique toute activité novatrice, tout rapport au savoir, s’est trouvée mobilisée dans l’invention de la psychanalyse, dans les extensions de sa pratique et dans son épistémologie. Jusqu’alors circonscrite dans le champ de la cure individuelle, une autre modalité de la « psychanalyse transgressive » est apparue avec l’invention psychanalytique du groupe. Le dispositif plurisubjectif, la complexité des espaces de la réalité psychique distincts et interférents, la spécificité de l’expérience qui s’y effectue ont requis l’élaboration d’un modèle métapsychologique capable de rendre compte des transformations de notre représentation de l’inconscient.
Transgressions
Authors: Ravit Magali
Published: April 2024

La clinique du passage à l’acte met à mal nos capacités de liaison interne et agit comme une onde de choc traumatique. Les effets de fascination produits par cette clinique seraient à prendre en considération comme une défense anti-traumatique venant lutter contre un vécu d’intrusion psychique. Autrement dit, la fascination opérerait comme une érotisation du violent et du traumatique alors mis en figuration dans une surenchère du sensoriel, face à la mort. La fascination serait marquée par une prime de satisfaction à pouvoir survivre au désespoir, là où se fige l’expérience intense d’effroi conduisant au meurtre de la subjectivité. À cet égard, la présentation d’une séquence clinique de groupe à médiation photolangage vient éclairer comment l’emboîtement des espaces (groupe, photo) relance les processus associatifs autour d’expériences limites de négociation identitaire.
Troubles de l’Usage d’Alcool (TUA) au CHU Kara : état des lieux
Authors: Wenkourama Daméga , Bakowè Ayelou , I. N. Eli Ataigba , Kanékatoua Sonia , Kpinsaga Mayéna , Bouwèssotcholo Agouda , Babizam Awesso , Soedje Kokou Messanh Agbemele , Dassa Kolou Simliwa
Published: April 2024

Introduction : Les Troubles de l’Usage d’Alcool représentent un enjeu prioritaire de santé publique, tant par leur fréquence que par la sévérité des dommages sanitaires ou sociaux induits. Objectif : Faire l’état des lieux des troubles de l’usage d’alcool au CHU Kara Méthodologie : Il s’agit d’une étude transversale, descriptive portant sur les dossiers médicaux de 107 patients ayant souffert de TUA dans le service de psychiatrie du CHU Kara entre le 1er janvier 2019 et le 30 juin 2023. Résultats : Les résultats ont montré une prédominance masculine avec un sexe ratio H/F de 8.72, un âge moyen de 42.6 ans. Les mariés étaient majoritaires (68.22 %) et les enseignants étaient les plus représentés (21.50 %). Les troubles de l’humeur étaient les plus associés aux TUA qui étaient les plus présents dans les antécédents familiaux. Les enquêtés étaient plus amenés à consommer de l’alcool en compagnie des amis. Dans la prise en charge, ils étaient pour la plupart suivis en ambulatoire et les médicaments de réduction du craving étaient les plus utilisés dans la thérapie. Le suivi était respecté par 37.38 % des enquêtés et 14.95 % avaient adopté et maintenu l’abstinence à l’alcool. Conclusion : Les TUA sont réels avec des conséquences néfastes mais la prise en charge lorsqu’elle est bien suivie donne de bons résultats qui restent encore à améliorer.
Les pénibilités intimes du travail d’enseignante. Dans les murs, une usure sourde
Authors: Jarty Julie
Published: April 2024

Sous l’effet d’un androcentrisme des sciences, les pénibilités enseignantes ont surtout été appréhendées sous le prisme des conditions « objectives » de travail. Issu d’une recherche sociologique au long cours, et adoptant une perspective féministe, cet article se propose de mettre en lumière les pénibilités intimes qui échappent le plus souvent à l’analyse sociologique et subjective des souffrances enseignantes en France. Il entrevoit tour à tour, et de façon dialectique, pénibilités corporelle, maternelle et sexuelle, habituellement tues. Prenant la forme de maltraitances organisationnelles atténuées par leur banalité, leur indicibilité et leur subséquente acceptation, ces trois formes de pénibilité font pourtant le lit de logiques de dévalorisation professionnelle et de fragilisation de la santé mentale des femmes. Cet article plaide alors pour une attention scientifique à l’intime dans les organisations, à l’image d’enseignantes féministes qui s’en saisissent pour faire reconnaître ce qui émaille et altère leur quotidien professionnel.
Une tonne de plumes pèse autant qu’une tonne de plomb. Vers la reconnaissance et l’élimination des dangers dans le travail des femmes au Québec
Authors: Messing Karen , Cox Rachel
Published: April 2024

Les problèmes de santé au travail des femmes diffèrent de ceux des hommes, du fait de la ségrégation des professions et des tâches assignées à l’intérieur de celles-ci, entre autres. Les risques qu’elles encourent étant moins visibles, les femmes peuvent hésiter à les rapporter, par crainte d’être perçues comme faibles et par souci de protéger leur accès à l’emploi. Cette situation, qui oppose la recherche de la santé à la visée de l’égalité, entrave leur avancement professionnel et entraine une sous-reconnaissance des lésions professionnelles. Nous présentons les enjeux révélés par une réforme du régime québécois, relative à la santé et la sécurité au travail, à l’aune de l’inclusion des « spécificités » du corps et du rôle social des femmes, et analysons certaines améliorations obtenues lors des débats parlementaires en 2020-2021 par une coalition de chercheuses, syndicats, organisations féministes et intervenantes en santé publique.
Double inertial steps extragadient-type methods for solving optimal control and image restoration problems
Authors: Ofem Austine Efut , Abuchu Jacob Ashiwere , Ugwunnadi Godwin Chidi , Nabwey Hossam A. , Adamu Abubakar , Narain Ojen Kumar
Published: April 2024

In order to approximate the common solution of quasi-nonexpansive fixed point and pseudo-monotone variational inequality problems in real Hilbert spaces, this paper presented three new modified sub-gradient extragradient-type methods. Our algorithms incorporated viscosity terms and double inertial extrapolations to ensure strong convergence and to speed up convergence. No line search methods of the Armijo type were required by our algorithms. Instead, they employed a novel self-adaptive step size technique that produced a non-monotonic sequence of step sizes while also correctly incorporating a number of well-known step sizes. The step size was designed to lessen the algorithms' reliance on the initial step size. Numerical tests were performed, and the results showed that our step size is more effective and that it guarantees that our methods require less execution time. We stated and proved the strong convergence of our algorithms under mild conditions imposed on the control parameters. To show the computational advantage of the suggested methods over some well-known methods in the literature, several numerical experiments were provided. To test the applicability and efficiencies of our methods in solving real-world problems, we utilized the proposed methods to solve optimal control and image restoration problems.
Investigation of multi-term delay fractional differential equations with integro-multipoint boundary conditions
Authors: Alghamdi Najla , Ahmad Bashir , Alharbi Esraa Abed , Shammakh Wafa
Published: April 2024

A new class of nonlocal boundary value problems consisting of multi-term delay fractional differential equations and multipoint-integral boundary conditions is studied in this paper. We derive a more general form of the solution for the given problem by applying a fractional integral operator of an arbitrary order $ \beta_{\xi} $ instead of $ \beta_{1} $; for details, see Lemma 2. The given problem is converted into an equivalent fixed-point problem to apply the tools of fixed-point theory. The existence of solutions for the given problem is established through the use of a nonlinear alternative of the Leray-Schauder theorem, while the uniqueness of its solutions is shown with the aid of Banach's fixed-point theorem. We also discuss the stability criteria, icluding Ulam-Hyers, generalized Ulam-Hyers, Ulam-Hyers-Rassias, and generalized Ulam-Hyers-Rassias stability, for solutions of the problem at hand. For illustration of the abstract results, we present examples. Our results are new and useful for the discipline of multi-term fractional differential equations related to hydrodynamics. The paper concludes with some interesting observations.
Transmission dynamics of breast cancer through Caputo Fabrizio fractional derivative operator with real data
Authors: Chavada Anil , Pathak Nimisha
Published: April 2024

In this paper, we studied the dynamical behavior of various phases of breast cancer using the Caputo Fabrizio (CF) fractional order derivative operator. The Picard-Lindelof (PL) method was used to investigate the existence and uniqueness of the proposed system. Moreover, we investigated the stability of the system in the sense of Ulam Hyers (UH) criteria. In addition, the two-step Adams-Bashforth (AB) technique was employed to simulate our methodology. The fractional model was then simulated using real data, which includes reported breast cancer incidences among females of Saudi Arabia from 2004 to 2016. The real data was used to determine the values of the parameters that were fitted using the least squares method. Also, residuals were computed for the integer as well as fractional-order models. Based on the results obtained, the CF model's efficacy rates were greater than those of the existing classical model. Graphical representations were used to illustrate numerical results by examining different choices of fractional order parameters, then the dynamical behavior of several phases of breast cancer was quantified to show how fractional order affects breast cancer behavior and how chemotherapy rate affects breast cancer behavior. We provided graphical results for a breast cancer model with effective parameters, resulting in fewer future incidences in the population of phases Ⅲ and Ⅳ as well as the disease-free state. Chemotherapy often raises the risk of cardiotoxicity, and our proposed model output reflected this. The goal of this study was to reduce the incidence of cardiotoxicity in chemotherapy patients while also increasing the pace of patient recovery. This research has the potential to significantly improve outcomes of patients and provide information of treatment strategies for breast cancer patients.
Influence of dietary patterns in the pathophysiology of Huntington's Disease: A literature review
Authors: Ansari Ubaid , Nadora Dawnica , Alam Meraj , Wen Jimmy , Asad Shaheryar , Lui Forshing
Published: April 2024

Huntington's disease (HD), a rare autosomal dominant neurodegenerative disease, causes the gradual deterioration of neurons in the basal ganglia, specifically in the striatum. HD displays a wide range of symptoms, from motor disturbances such as chorea, dystonia, and bradykinesia to more debilitating symptoms such as cognitive decline, behavioral abnormalities, and psychiatric disturbances. Current research suggests the potential use of dietary interventions as viable strategies for slowing the progression of HD. Most notably, the Mediterranean, vegan, carnivore, paleo, and ketogenic diets have gained attention due to their hypothesized impact on neuroprotection and symptomatic modulation in various neurodegenerative disorders. Despite substantial nutritional differences among these diets, they share a fundamental premise—that dietary factors have an influential impact in modifying pertinent biological pathways linked to neurodegeneration. Understanding the intricate interactions between these dietary regimens and HD pathogenesis could open avenues for personalized interventions tailored to the individual's specific needs and genetic background. Ultimately, elucidating the multifaceted effects of these diets on HD offers a promising framework for developing comprehensive therapeutic approaches that integrate dietary strategies with conventional treatments.
Secondary sex estimation using morphological traits from the cranium and mandible: application to two Merovingian populations from Belgium
Authors: Chevalier Bérénice , Santos Frédéric , Polet Caroline , Villotte Sébastien
Published: April 2024

Il est généralement admis que l’os coxal est l’os le plus fiable pour l’estimation du sexe chez les sujets adultes. Lorsque ce dernier n’est pas exploitable, les chercheurs se tournent généralement vers des méthodes basées sur le crâne (le bloc crânio-facial et la mandibule). Or, ces méthodes sont moins fiables, car elles reposent en grande partie sur une estimation de la robustesse, qui peut être influencée par des caractéristiques indépendantes du sexe du sujet. Dans le contexte de la diagnose sexuelle primaire, les estimations basées sur le crâne devraient ainsi être évitées. Toutefois, l’utilisation de traits morphologiques du bloc crânio-facial et de la mandibule dans le cadre d’une diagnose sexuelle secondaire nous a permis d’estimer le sexe d’un nombre relativement important d’individus avec une fiabilité minimum de 95 %. Notre étude illustre ainsi l’intérêt d’utiliser des caractéristiques morphologiques du crâne lors d’une diagnose secondaire réalisée avec une méthode statistique fiable.
Fabrication of Multi-Layer 316L-TiC Composite by Selective Laser Melting Additive Manufacturing
Authors: Yazdani Sasan , Tekeli Süleyman , Akbarzadeh-CH Elina
Published: April 2024

In this study, the microstructure and wear behavior of multilayer 316L stainless steel/TiC composite fabricated using selective laser melting (SLM) additive manufacturing were investigated. The produced samples consisted of three layers: 316L, 316L-5TiC, and 316L-10TiC (wt%). Microstructural evaluations revealed a homogeneous distribution of TiC particles in the matrix of the composite layers, with no cracks observed at the interfaces between layers, indicating a robust bond between the layers. Wear tests showed that the incorporation of TiC particles enhanced wear resistance, with the composite layer with 10 wt% TiC exhibiting the best wear resistance due to the hardness and reinforcing nature of TiC. Wear mechanisms included abrasive wear and fatigue wear due to fragmentation of TiC particles. The results suggest that SLM manufacturing can potentially be used to produce functionally graded composites for applications requiring high strength and wear resistance.
Improving of Machining Efficiency of Threads and Conical Surfaces of Diverse Directions by Managing Static Technological Relationships
Authors: Rasulov Nariman , Nadirov Ugurlu , Abbasova Irada
Published: April 2024

In the work, the design of the tool – boring bar for parallel machining of conical surfaces and threads in coupling-type parts with opposite directions, same inclination, coaxial conical surfaces and threads is given, and their generalized design features are presented for the machining of couplings of different types and sizes. With the application of the designed tool - boring bar to machining of inner surfaces of couplings, their machining accuracy, especially accuracy of coaxiality of threads, thus the load-carrying capacity of the couplings increases, the technological cost of their production is reduced, and the efficiency of their use is ensured.
Anti-Vibration Foundation for the Machines Used in the Oil and Gas Industry
Authors: Bakhshali Valeh
Published: April 2024

The result of the research aims to provide a foundation structure that reduces the amplitude of oscillation of machines and equipment from various technical causes and natural phenomena, preventing resonant phenomena and economical use of foundation material. The proposed foundation, compared to existing foundations, provides a decrease in amplitude and prevents the phenomenon of resonance of vibrations of foundations for machines and equipment creating savings in the use of cement-concrete material. There is considered mathematical, structural, and practical modeling of anti-vibration foundations of mechanical installations in this article. The purpose of the study is to create a foundation design that reduces the amplitude of oscillation of structures from various technical reasons and natural phenomena, prevents resonant phenomena, and economical use of foundation-reinforced concrete material. The research results can be used in the design of foundations of piston machines and equipment used in the oil and gas industry.
Sustainable Development Goals: The Case of Industrial Ecology
Authors: Heydarov Aydın
Published: April 2024

Environmentally targeted regulation of material and energy flows in the regional area, which is part of the philosophy of industrial ecology, should be considered taking into account both the welfare of the population and economic interests. Thinking of logistics as the science of managing complex flows in networks provides a scientific basis for logistics and industrial ecology, as well as enabling the movement of resources in socio-economic systems in an economically highly efficient manner. It aimed to achieve the sustainable development goals of industrial systems at different hierarchical levels. These two areas complement each other and create a new integrated development vector for the sustainable development paradigm. In this case, it is very important to understand the concept of management well. Although in both industrial ecology and logistics material flow is studied from physical, environmental and socio-economic perspectives, in logistics it is from physical and socio-economic perspectives. Combining these two components and the foundations of the disciplines will create a new and sustainable basis for policies and mechanisms for the development of regions. In the article, the example of industrial ecology is mentioned as the goals of sustainable development.
Development of Production Technology for the Valve of Steel Drilling Pump Brand of PK08Х4Н5
Authors: Namazov Subhan , Taghiyev Taleh , Mashayev Shahin
Published: April 2024

One of the most important issues in the procurement of parts and products by the process of metallurgy is the design of the details of the press-mold. The design should be carried out in such a way that the additional mechanical processing of the purchased parts and products is minimal. The tooling and technological scheme of the press-mold should be selected as might it be economically viable and the mechanical processing stakes are small. For these purposes, in this present study, the valve part of the high-pressure drilling pump НП-720х105, which is widely used in the oil and gas complex, was selected for theoretical and experimental investigations. With the help of the software, in order to ensure equal distribution of residual porosity in the samples, the optimal size and configuration of the samples were determined, and the inner and outer conical walls of the asymmetric samples were subjected to dynamic hot pressing. "Valve seat" and "valve tray" of the НП-720х105 high-pressure three-plunger pump were used for the experimental studies. From the conducted tests, it became clear that during the preparation of abrasive steels with high impact-abrasive corrosion resistance, it is necessary to thoroughly study the chemical and granulometric composition, structure, and strengthening process. Theoretical and experimental results show that the technology of manufacturing parts resistant to impact-abrasive corrosion allows the obtained parts to work in conditions of high impact-hydroabrasive corrosion.
Punches and Matrices Recovery for Hot Punching by Electric Arc Hardfacing
Authors: Savin Igor A. , Shaparev Alexander V. , Ptichkin Sergey N. , Khankishiyev Isag , Mirzayev Asim
Published: April 2024

The technology repair and restoration dies for hot punching is considered. During the overhaul the hammer die, a layer of metal is removed from the side the mirror to the entire depth the cavity of the stream, then the figure the new stream is marked, and then the stream is milled as in a new punch. Sometimes such methods restoring punches as electric arc surfacing welding or deformation with a special punch in the form of a stream are used. When installing inserts in a punch, it is necessary to compensate for the removed metal layer with special linings. Welding electrodes must be selected depending on the requirements for the base metal and service properties the deposited layer – hardness, heat resistance, allowable specific pressures, machinability, heat treatment acceptance, etc.
Research on Ratio Regulation Gear Differential Closed by a Continuously Variable Transmission (CVT)
Authors: Mammadov Firuz , Baghirova Samaya
Published: April 2024

Over the past two decades, numerous research efforts have been aimed at developing efficient transmissions, in particular automotive ones, which can significantly reduce energy consumption and improve the dynamic properties of the car. The driving performance of a vehicle is one of the most important qualities that ensures comfortable movement of the passenger, which also affects traffic safety. One way to achieve this goal is to use transmissions that provide continuously variable control. gear ratio. The Continuously Variable Transmission (CVT) provides continuous shifting, changing the ratio between the input and output shafts within the desired range, which consequently improves fuel economy and vehicle performance by better matching engine operating conditions to changing road conditions. This article discusses the possibility of using composite transmissions - gear differential mechanisms closed by (CVT). Various schemes of composite transmissions are given. The conditions under which the transmission ratio of the entire transmission must be changed by changing the transmission ratio (CVT) included in the combined transmission have been studied.
Analysis of the Speed of Sound in Solutions of Ionic Liquids with Methanol
Authors: Kalbiyev Ramiz , Hamidova Rana , Abdullayeva Gulyaz
Published: April 2024

This article presents the dependence of the speed of sound u/m•s-1 of binary solutions of 1-ethyl-3-methylimidazolium methanesulfonate [EMIM][MeSO3], 1-butyl-3-methylimidazolium hexafluorophosphate [BMIM][PF6] or 1-Butyl-3-methylimidazolium tris(pentafluoroethyl) trifluorophosphate [BMIM][FAP] with methanol. The experiments were carried out at temperatures T=(278.15–343.15) K using a vibration densimeter and an Anton-Paar DSA 5000M sound speed meter with an error of Δu/u=0.1 m•s-1. The studied solutions are intended for use in solar thermal collectors, absorption refrigeration units and heat pumps.