bluuebunny/crossref_metadata_2025 huggingface dataset:
Hybridization of Block-Pulse and Taylor Polynomials for Approximating 2D Fractional Volterra Integral Equations
Authors: Sabegh Davood Jabari , Ezzati Reza , Nikan Omid , Lopes António M. , Galhano Alexandra M. S. F.
Published: September 2022

This paper proposes an accurate numerical approach for computing the solution of two-dimensional fractional Volterra integral equations. The operational matrices of fractional integration based on the Hybridization of block-pulse and Taylor polynomials are implemented to transform these equations into a system of linear algebraic equations. The error analysis of the proposed method is examined in detail. Numerical results highlight the robustness and accuracy of the proposed strategy.
New Numerical Approach of Solving Highly Nonlinear Fractional Partial Differential Equations via Fractional Novel Analytical Method
Authors: Sultana Mariam , Arshad Uroosa , Abdel-Aty Abdel-Haleem , Akgül Ali , Mahmoud Mona , Eleuch Hichem
Published: September 2022

In this work, the fractional novel analytic method (FNAM) is successfully implemented on some well-known, strongly nonlinear fractional partial differential equations (NFPDEs), and the results show the approach’s efficiency. The main purpose is to show the method’s strength on FPDEs by minimizing the calculation effort. The novel numerical approach has shown to be the simplest technique for obtaining the numerical solution to any form of the fractional partial differential equation (FPDE).
Testing the Sediment Organic Contents Required for Biogenic Gas Hydrate Formation: Insights from Synthetic 3-D Basin and Hydrocarbon System Modelling
Authors: Burton Zachary F. M. , Dafov Laura N.
Published: September 2022

Gas hydrates comprise one of the largest reservoirs of organic carbon on Earth. Marine gas hydrate predominantly consists of biogenic (i.e., microbially generated) methane molecules trapped within lattice-like cages of frozen water molecules. Sedimentary organic matter is the feedstock for methanogens producing gas in anaerobic sub-seafloor environments. Therefore, an understanding of the minimum amount of organic material (measured as carbon and hydrogen content) necessary for methanogenesis to result in appreciable volumes of hydrocarbons is central to understanding the requirements for gas hydrate formation. Reactive transport modelling by workers over the past 20 years suggests minimum requirements of ~0.3–0.5. wt. % TOC (total organic carbon) for gas hydrate formation, while earlier workers predicted TOC as low as ~0.1–0.2. wt. % could produce biogenic gas. However, the hydrogen content (recognized as the limiting reagent in hydrocarbon generation for over 50 years) needed for biogenic gas generation and gas hydrate formation is poorly understood. Furthermore, the minimum organic contents needed for gas hydrate formation have not been investigated via basin-scale computational modeling. Here, we construct a synthetic 3-D basin and gas hydrate system model to investigate minimum sediment TOC and hydrogen (HI, hydrogen index) contents needed for gas hydrate formation. Our modelling suggests that, under geologically favorable conditions, TOC as low as 0.1. wt. % (paired with 100 HI) and HI as low as 50 (paired with 0.2. wt. % TOC) may produce biogenic gas hydrate saturations above 1%. Our modelling demonstrates the importance of basin-scale investigation of hydrocarbon systems and demonstrates how the confluence of favorable structural controls (e.g., faults, folds, anticlines) and stratigraphic controls (e.g., carrier beds, reservoirs) can result in gas hydrate accumulations, even in organic-poor settings.
Compatibility Evaluation of In-Depth Profile Control Agents for Low-Permeability Fractured Reservoirs
Authors: Li Xuanran , Wang Jincai , Ni Jun , Fu Libing , Xu Anzhu , Zhao Lun
Published: September 2022

Under the background that the in-depth profile control technology is gradually applied in low-permeability fractured reservoirs, this paper regards block H of Changqing Oilfield as the research object, referring to the range of its physical parameters and field application data. Three common in-depth profile control agents (PCAs), nanosphere suspension, poly(ethylene glycol) single-phase gel particle (PEG) and cross-linked bulk gel and swelling particle (CBG-SP), are selected to investigate the compatibility between the fractured channels and the PCAs through a series of experiments. The experimental results show that the nanospheres with particle sizes of 100 nm and 300 nm have good injectivity and deep migration ability, which remains the overall core plugging rate at a high level. The residual resistance coefficient of 800 nm nanospheres decreases in a “cliff” manner along the injection direction due to the formation of blockage in the front section, resulting in a very low plugging rate in the rear section. The injection rate is an important parameter that affects the effect of PEG in the fractured channels. When the injection rate is lower than 0.1 mL/min, the plugging ability will be weakened, and if the injection rate is higher than 0.2 mL/min, the core plugging will occur. The appropriate injection rate will promote the better effect of PEG with the plugging rate > 90%. The average plugging rate of CBG-SP in fractured rock core is about 80%, and the overall control and displacement effect is good. Based on the experimental data of PCAs, the optimization criteria of slug configuration and pro-duction parameters are proposed. According to the principle “blocking, controlling and displacing”, references are provided for PCAs screening and parameters selection of field implementation.
Dynamic Covalent Hydrogels: Strong yet Dynamic
Authors: Han Yueying , Cao Yi , Lei Hai
Published: September 2022

Hydrogels are crosslinked polymer networks with time-dependent mechanical response. The overall mechanical properties are correlated with the dynamics of the crosslinks. Generally, hydrogels crosslinked by permanent chemical crosslinks are strong but static, while hydrogels crosslinked by physical interactions are weak but dynamic. It is highly desirable to create synthetic hydrogels that possess strong mechanical stability yet remain dynamic for various applications, such as drug delivery cargos, tissue engineering scaffolds, and shape-memory materials. Recently, with the introduction of dynamic covalent chemistry, the seemingly conflicting mechanical properties, i.e., stability and dynamics, have been successfully combined in the same hydrogels. Dynamic covalent bonds are mechanically stable yet still capable of exchanging, dissociating, or switching in response to external stimuli, empowering the hydrogels with self-healing properties, injectability and suitability for postprocessing and additive manufacturing. Here in this review, we first summarize the common dynamic covalent bonds used in hydrogel networks based on various chemical reaction mechanisms and the mechanical strength of these bonds at the single molecule level. Next, we discuss how dynamic covalent chemistry makes hydrogel materials more dynamic from the materials perspective. Furthermore, we highlight the challenges and future perspectives of dynamic covalent hydrogels.
Individual Genetic Heterogeneity
Authors: Vihinen Mauno
Published: September 2022

Genetic variation has been widely covered in literature, however, not from the perspective of an individual in any species. Here, a synthesis of genetic concepts and variations relevant for individual genetic constitution is provided. All the different levels of genetic information and variation are covered, ranging from whether an organism is unmixed or hybrid, has variations in genome, chromosomes, and more locally in DNA regions, to epigenetic variants or alterations in selfish genetic elements. Genetic constitution and heterogeneity of microbiota are highly relevant for health and wellbeing of an individual. Mutation rates vary widely for variation types, e.g., due to the sequence context. Genetic information guides numerous aspects in organisms. Types of inheritance, whether Mendelian or non-Mendelian, zygosity, sexual reproduction, and sex determination are covered. Functions of DNA and functional effects of variations are introduced, along with mechanism that reduce and modulate functional effects, including TARAR countermeasures and intraindividual genetic conflict. TARAR countermeasures for tolerance, avoidance, repair, attenuation, and resistance are essential for life, integrity of genetic information, and gene expression. The genetic composition, effects of variations, and their expression are considered also in diseases and personalized medicine. The text synthesizes knowledge and insight on individual genetic heterogeneity and organizes and systematizes the central concepts.
Identification of Epigenetic Interactions between miRNA and Gene Expression as Potential Prognostic Markers in Bladder Cancer
Authors: Awadalla Amira , Abol-Enein Hassan , Hamam Eman T. , Ahmed Asmaa E. , Khirallah Salma M. , El-Assmy Ahmed , Mostafa Sally Abdallah , Babalghith Ahmed O. , Ali Mohamed , Abdel-Rahim Mona , Shokeir Ahmed A. , Harraz Ahmed M.
Published: September 2022

Purpose: To identify the role of a set of microRNAs and their target genes and protein expression levels in the pathogenesis of bladder cancer with a muscular invasion (T2–T4) and non-muscular invasion (T1). Methods: In 157 patients, bladder specimen was examined for the expression of a set of miRNAs including let-7a-5p, miRNA-449a-5p, miRNA-145-3P, miRNA-124-3P, miRNA-138-5p, and miRNA-23a-5p and their targeted genes; β-catenin, WNT7A, IRS2, FZD4, SOS1, HDAC1, HDAC2, HIF1α, and PTEN using the qRT-PCR technique. The prognostic effect of miRNAs and their targeted genes on cancer-specific survival (CSS) was evaluated in pT2–pT4 stages. Results: pT1 was found in 40 patients while pT2–4 was found in 117 patients. The expression of let-7a-5P, miR-124-3P, miR-449a-5P, and miR-138-5P significantly decreased in pT2–4 compared with pT1 (p < 0.001), in contrast, miR-23a-5P increased significantly in pT2–pT4 compared with pT1 (p < 0.001). Moreover, the expression of miR-145 did not show a significant change (p = 0.31). Higher expression levels of WNT7A, β-catenin, IRS2, FZD4, and SOS1 genes were observed in pT2–pT4 compared with pT1, whereas HDAC1, HDAC2, HIF1α, and PTEN genes were downregulated in pT2–pT4 compared with pT1. Lower CSS was significantly associated with lower expression of let-7a-5P, miR-124-3P, miR-449a-5P, and miR-138-5P. Higher expression of β-catenin, FZD4, IRS2, WNT7a, and SOS1 was significantly associated with worse CSS. In contrast, lower levels of HDAC1, HDAC2, HIF1α, and PTEN were associated with lower CSS. Conclusion: Our results support let-7a-5P, miR-124-3P, miR-138-5P, and their target genes can be developed as accurate biomarkers for prognosis in bladder cancer with a muscular invasion.
Exome Sequencing Identified Molecular Determinants of Retinal Dystrophies in Nine Consanguineous Pakistani Families
Authors: Tehreem Raeesa , Chen Iris , Shah Mudassar Raza , Li Yumei , Khan Muzammil Ahmad , Afshan Kiran , Chen Rui , Firasat Sabika
Published: September 2022

Inherited retinal dystrophies (IRDs) are a heterogeneous group of degenerative disorders of the retina. Retinitis Pigmentosa (RP) is a common type of IRD that causes night blindness and loss of peripheral vision and may progress to blindness. Mutations in more than 300 genes have been associated with syndromic and non-syndromic IRDs. Recessive forms are more frequent in populations where endogamy is a social preference, such as Pakistan. The aim of this study was to identify molecular determinants of IRDs with the common presentation of night blindness in consanguineous Pakistani families. This study included nine consanguineous IRD-affected families that presented autosomal recessive inheritance of the night blindness phenotype. DNA was extracted from blood samples. Targeted exome sequencing of 344 known genes for retinal dystrophies was performed. Screening of nine affected families revealed two novel (c.5571_5576delinsCTAGATand c.471dup in EYS and SPATA7 genes, respectively) and six reported pathogenic mutations (c.304C>A, c.187C>T, c.1560C>A, c.547C>T, c.109del and c.9911_11550del in PDE6A, USH2A, USH2A, NMNAT1, PAX6 and ALMS1 genes, respectively) segregating with disease phenotype in each respective family. Molecular determinants of hereditary retinal dystrophies were identified in all screened families. Identification of novel variants aid future diagnosis of retinal dystrophies and help to provide genetic counseling to affected families.
Correction: Fraik et al. The Impacts of Dam Construction and Removal on the Genetics of Recovering Steelhead (Oncorhynchus mykiss) Populations across the Elwha River Watershed. Genes 2021, 12, 89
Authors: Fraik Alexandra K. , McMillan John R. , Liermann Martin , Bennett Todd , McHenry Michael L. , McKinney Garrett J. , Wells Abigail H. , Winans Gary , Kelley Joanna L. , Pess George R. , Nichols Krista M.
Published: September 2022

In the original publication [...]
Fruit Characterization of Prunus serotina subsp. capuli
Authors: Pathania Sakshi , Itle Rachel A. , Chávez Carlos R. , Lema Luis F. , Caballero-Serrano Veronica , Carrasco Juan C. , Chavez Dario J.
Published: September 2022

Prunus serotina is divided into five subspecies. Among these, P. serotina subsp. capuli, commonly known as capuli, is native to Central and South America. Its fruits are big, sweet, and consumed by locals in various forms, with the Ecuadorian Andes region providing the best fruit forms of capuli. The objective of this study was to characterize a collection of different genotypes of capuli’s fruit, and their endocarps, found growing in the wild in the Chimborazo, Tungurahua, and Cotopaxi provinces of Ecuador. The fruits were characterized for weight (11.7–50.3 g), diameter (12.4–21.7 mm), height (11.4–19.7 mm), and soluble solids content (SSC) (13.4–27.6 °Brix) across two years. Similarly, the endocarps’ diameters (7.5–12.2 mm) and heights (8.1–13.6 mm) were measured. Significant differences were found for all the fruit and endocarp variables studied. A multivariate analysis showed that all the fruit and endocarp size characteristics, except SSC, were positively correlated with each other within a season. No clear population differentiation was seen among the genotypes from different provinces, suggesting a lack of clear morphological differentiation. The future breeding and selection of a capuli with superior, commercial, large fruit and a high SSC shows great potential.
Lessons Learned from the 2019 Nebraska Floods: Implications for Emergency Management, Mass Care, and Food Security
Authors: Calloway Eric E. , Nugent Nadine B. , Stern Katie L. , Mueller Ashley , Yaroch Amy L.
Published: September 2022

This qualitative study aimed to understand the actions, challenges, and lessons learned for addressing the food and water needs of flood survivors, with a special focus on vulnerable populations and the implications for food security, to inform future disaster response efforts in the U.S. Semi-structured in-depth interviews were conducted from January to August 2020 with the local, state, and national stakeholders (n = 27) involved in the disaster response to the 2019 Nebraska floods, particularly those involved in providing mass care, such as food, water, and shelter, for the flood survivors. The challenge themes were related to limited risk awareness and apathy, the large scope of the impact, the difficulty with coordination and communication, the challenges in risk communication, the limited local-level capacity, and the perceived stigma and fear limiting the utilization of governmental assistance. The mitigation recommendations included the need to consider zoning and infrastructure updates, the implementation of efficient systems that leverage technology for coordination and communication, and guidance on how to address certain human factors. This study reinforces previous findings related to flood disasters and adds to our understanding of disaster response and food insecurity. The practical takeaways from this study can inform future flood-related disaster mitigation approaches in Nebraska and other rural areas.
Study on the Changes in Immobilized Petroleum–Degrading Bacteria Beads in a Continuous Bioreactor Related to Physicochemical Performance, Degradation Ability, and Microbial Community
Authors: Liu Yixuan , Li Weisi , Qiao Yanlu , Yu Fangying , Wang Bowen , Xue Jianliang , Wang Mianmian , Jiang Qing , Zhou Zhibin
Published: September 2022

Continuous bioreactors for petroleum degradation and the effect factors of these bioreactors have rarely been mentioned in studies. In addition, indigenous bacteria living in seawater could influence the performance of continuous bioreactors with respect to petroleum degradation in practice. In this paper, a bioreactor fitted with immobilized petroleum–degrading bacteria beads was designed for further research. The results indicated that the diesel degradation rate of the bioreactor could remain above 50% over 27 days, while degradation performance decreased with bioremediation time. Intriguingly, the diameters of immobilized petroleum–degrading bacteria beads were reduced by 32.49% after 45 days remediation compared with the initial size of the immobilized petroleum–degrading bacteria beads. Change in immobilized petroleum–degrading bacteria beads was considered to correlate remarkably with reduced degradation efficiency. Therefore, this paper will be helpful for further study and improvement of bioreactors in the practical context of oil-spill accident recovery.
Gap between Willingness and Behaviors: Understanding the Consistency of Farmers’ Green Production in Hainan, China
Authors: Qiao Dan , Xu Shuting , Xu Tao , Hao Qinchuan , Zhong Zhen
Published: September 2022

The green transformation of production modes plays an essential role in the sustainable development of China’s agriculture and the modernization process, but there is often a deviation between farmers’ behavior and their willingness regarding green production. This paper analyzed the factors influencing the deviation of farmers’ green production behaviors from their willingness, along with their hierarchical logic structure, using the ordered logit model and ISM model with field survey data of 436 households in Hainan Province. The results show that: (1) there are deviations between farmers’ green production behavior and willingness; (2) age, number of dependents, peer influence, and social networks aggravate farmers’ green production behavior–willingness deviation, while ethnicity, education, land fragmentation, agricultural expenditure, land transfer, neighborhood learning, and green production cognition mitigate the deviation; (3) among the significant influencing factors, farmers’ perceptions of green production, peer influence, land transfer, and agricultural expenditure are the direct surface factors, while neighborhood learning, land fragmentation, and number of dependents are the middle indirect factors, and farmers’ education, social networks, age, and ethnicity are the deep-rooted factors. This study sheds more light and detail on the understanding of the factors influencing farmers’ green production behavior–willingness deviation, and provides more practical and relevant guidance for the agricultural green development in tropical China.
Searching for New Human Behavior Model in Explaining Energy Transition: Exploring the Impact of Value and Perception Factors on Inconsistency of Attitude toward Policy Support and Intention to Pay for Energy Transition
Authors: Oh Yoonjung , Kim Seoyong , Kim Sohee
Published: September 2022

The purpose of this study is to compare and analyze the factors influencing the public’s attitude toward policy support and intention to pay for energy transition from nuclear to renewable energy. We focus on inconsistency issues between attitude and intention. To this end, we set the attitude toward policy support and behavioral intention to pay as dependent variables, and value factors (i.e., ideology, political support for the current Moon Jae-in government, environmentalism, and science-technology optimism) and perception factors (i.e., perceived risk, benefit, knowledge, and trust) as the independent variables. Based on a survey, the analysis showed that at the variable level, the perceived benefits and trust in renewable energy and perceived risks and benefits in nuclear energy influenced the attitude toward policy support and the intention to pay for energy transition. Second, when evaluating the explanatory power of independent variables, the attitude toward the energy transition was affected in the following order: (1) perceived benefit in nuclear power (β = 0.259) > (2) perceived benefit in renewable energy (β = −0.219) > (3) perceived risk in nuclear energy (β = 0.202) > (4) Moon Jae-in government support (β = 0.146). On the other hand, behavioral intention to pay for energy transition was influenced in the following order: (1) trust in renewable energy (β = 0.252) > (2) Moon Jae-in government support (β = 0.154) > (3) perceived risk in nuclear energy (β = 0.139) > (4) perceived benefit in renewable energy (β = 0.099). Third, variables such as environmentalism, perceived benefit/risk/trust in renewable energy, and perceived benefit/risk in nuclear energy affected inconsistency between attitude toward policy support and intention to pay for energy transition.
Evaluating the Efficacy and Safety of Different Pterygium Surgeries: A Review of the Literature
Authors: Palewski Marcin , Budnik Agnieszka , Konopińska Joanna
Published: September 2022

The search for the “gold standard” in the surgical treatment of pterygium has been ongoing for over two decades. Despite the development of various surgical techniques, recurrence rates range from 6.7% to 88% depending on the method used. This review discusses the latest and most commonly used methods for the surgical removal of pterygium, primarily focusing on efficacy and safety. Moreover, this review includes articles that either evaluated or compared surgical methods and clinical trials for primary and recurrent pterygium. Limited data are available on combined methods as well as on the efficacy of adjuvant treatment. The use of adjuvant intraoperative mitomycin C (MMC) and conjunctival autografting (CAU) are the two most highly recommended options, as they have the lowest rates of postoperative recurrence.
Ultra-Processed Food Consumption and Relation with Diet Quality and Mediterranean Diet in Southern Italy
Authors: Godos Justyna , Giampieri Francesca , Al-Qahtani Wahidah H. , Scazzina Francesca , Bonaccio Marialaura , Grosso Giuseppe
Published: September 2022

Ultra-processed food (UPF) consumption has been the focus of major attention due to their potential effects on human health. The aim of this study was to investigate the intake of UPFs in a sample of southern Italian individuals and assess its relationship with nutrient profile and dietary quality parameters. A cross-sectional study was conducted on 1936 individuals older than 18 years randomly selected from the general population. A total of 110 food times have been categorized based on the level of processing using the NOVA classification. The average daily energy intake of the sample was 2091.1 kcal, 38.7% of which were from the NOVA group of unprocessed/minimally processed foods, 5.7% from processed culinary ingredients, 38.3% from processed foods, and 17.9% from the UPFs group. UPFs were more consumed among young, unmarried individuals, with high cultural level, smokers, and often eating out of home. The mean energy share of UPFs varied from 6.3% of total daily energy intake for individuals in the lowest quintile of UPF consumption to 34.2% for those in the upper quintile. Within the UPF group, the highest energy contribution was provided by fast foods and sweets. Compared to the lowest quintile of UPF consumption, individuals in the highest quintile consumed, on average, additional 300 kcals per day and less fiber. Some plant-derived vitamins, such as vitamin A and vitamin C showed an inverse trend toward increasing shares of UPF consumption, while sodium intake increased. A significant higher intake of UPFs in individuals meeting the European and Italian dietary recommendations for carbohydrates, vitamin B12, vitamin D, and vitamin E was found, while UPFs were less consumed among those meeting the recommendations for total fats, fiber, sodium, potassium, and vitamin C. Finally, individuals displaying a “healthier” dietary profile, such as higher adherence to either the Mediterranean diet, the Dietary Approaches to Stop Hypertension, the Alternate Diet Quality Index, and the Diet Quality Index-International, consumed less UPFs and more unprocessed/minimally processed foods, with minor variation in the other NOVA food categories. In conclusion, consumption of UPF in southern Italy is in line with those reported in some other Mediterranean countries, although it negatively impacted the nutrient profile. It is important to monitor the consumption of UPFs before their availability and popularity put the grounds on younger generations’ dietary habits.
Nutrition Knowledge, Dietary Habits, and Food Labels Use—A Representative Cross-Sectional Survey among Adults in Poland
Authors: Żarnowski Adam , Jankowski Mateusz , Gujski Mariusz
Published: September 2022

An unhealthy diet is an important risk factor for disability and premature death. This study aimed to assess nutrition knowledge, dietary habits, and food label use among adults in Poland as well as to identify factors associated with diet-related behaviors. A cross-sectional survey was carried out in July 2020 on a non-probability quota-based sample of 1070 adult citizens of Poland. The most common sources of nutrition knowledge were news websites (41.8%) or family/friends (32.4%). Over one-quarter of adults in Poland were on a diet (28.7%). Over one-tenth of respondents (11.9%) consumed less than three meals per day. Half of the respondents (50.3%) declared that they use food labels when shopping, and 15.4% checked the nutrition information on restaurant menus. Female gender (OR:1.70; 95%CI:1.26–2.29; p < 0.001), presence of chronic diseases (OR:1.83; 95%CI:1.37–2.44; p < 0.001), regular physical activity (p < 0.001), and being a non-smoker (OR:1.45; 95%CI:1.02–2.06; p = 0.04) were significantly associated with higher odds of being on a diet. Females (OR:1.63; 95%CI:1.24–2.15; p < 0.001), respondents with higher education (OR:1.53; 95%CI:1.17–2.01; p = 0.002), those who had never been married (OR:1.49; 95%CI:1.07–2.07; p = 0.02), respondents with chronic diseases (OR:1.73; 95%CI:1.30–2.31; p < 0.001), those with regular physical activity (p < 0.05), as well as non-smokers (OR:1.42; 95%CI:1.04–1.95; p = 0.03) had higher odds of checking the food labels. This study showed a significant gap in nutrition knowledge among adults in Poland.
Connecting Recreational Service to Visitor’s Well-Being: A Case Study in Qianjiangyuan National Park
Authors: Zhou Wenjia , Cai Jun , Chen Kai
Published: September 2022

Natural ecosystems provide service value to people in the region; especially in some nature reserves and national parks, the ecosystem recreational service function is more significant. It is worth paying attention to whether the recreational service function of this ecosystem can serve tourists outside the region and improve their well-being. Taking Qianjiangyuan National Park in China as the research site, based on the Spatially Explicit Ecosystem Services Comprehensive Assessment Model (ESTIMAP), we used the ecosystem services mapping tool to propose a comprehensive assessment framework for ecosystem recreational services and to explore the relationship between recreational services and the well-being of tourists. As a result, we identified the spatial distribution of the supply and demand flow paths of ecosystem recreational services and estimated that the actual flow of ecosystem recreational services was about 12.1 persons/km2 per year. In terms of personal well-being, ecosystem recreational services have a significant positive impact on tourists’ well-being. The service value is concentrated in amusement places and recreational activities, and dynamic recreational activities have a greater impact on tourists. The research results suggest that to improve the well-being of tourists and the value of ecosystem recreational services, national parks and nature reserves should improve accessibility and the participation of tourists in recreational activities.
Role of Enterprise Alliance in Carbon Emission Reduction Mechanism: An Evolutionary Game Analysis
Authors: Geng Jichao , Ji Meiyu , Yang Li
Published: September 2022

This study constructs the enterprise alliance game party, designs the mechanism for which the alliance and the government are jointly responsible for enterprise carbon emission reduction work, and explores the evolutionarily stable strategies (ESSs) of the government, enterprises, and enterprise alliance under the policy of carbon tax and carbon trading with numerical simulations. The results show that: (1) the ESSs of the enterprise alliance are always to give technical support to enterprises; (2) the carbon trading price below the critical value can mobilize the enthusiasm of enterprises for honest emission reduction; (3) the carbon tax rate has a negative correlation with enterprise emission reduction behavior; (4) when the underreported carbon emissions of enterprises exceed the critical value, the enterprise will evolve into dishonest emission reduction. The high carbon emissions underreported by enterprises will mobilize the enthusiasm of the government to choose supervision. This study may be of certain reference significance to optimize the existing carbon emission reduction mechanism and achieve win-win cooperation between enterprises and government in the carbon trading market.
Plasma Leptin and Adiponectin after a 4-Week Vegan Diet: A Randomized-Controlled Pilot Trial in Healthy Participants
Authors: Lederer Ann-Kathrin , Storz Maximilian Andreas , Huber Roman , Hannibal Luciana , Neumann Elena
Published: September 2022

Adiponectin and leptin are important mediators of metabolic homeostasis. The actions of these adipokines extend beyond adipocytes and include systemic modulation of lipid and glucose metabolism, nutrient flux, and the immune response to changes in nutrition. Herein, we hypothesized that short-term intervention with a vegan diet might result in an improvement of plasma concentrations of adiponectin and leptin and the leptin/adiponectin ratio. We investigated the response of plasma adiponectin and leptin to a 4-week intervention with a vegan or meat-rich diet and its associations with sex, BMI and nutritional intake. Fifty-three healthy, omnivore participants (62% female, average age 31 years and BMI 23.1 kg/m2) were randomly assigned to a vegan or meat-rich diet for 4 weeks. Plasma adiponectin and leptin were lower in men compared to women both at the beginning and end of the trial. The concentration of adiponectin in women was significantly higher both when comparing their transition from omnivorous to vegan diet (p = 0.023) and also for vegan versus meat-rich diet at the end of the trial (p = 0.001), whereas plasma leptin did not vary significantly. No changes in adiponectin were identified in men, yet an increase in leptin occurred upon their transition from an omnivorous to a meat-rich diet (p = 0.019). Examination of plasma adiponectin/leptin ratio, a proposed marker of cardiovascular risk, did not differ after 4-weeks of dietary intervention. Our study revealed that adiponectin and leptin concentrations are sensitive to short-term dietary intervention in a sex-dependent manner. This dietary modification of leptin and adiponectin not only occurs quickly as demonstrated in our study, but it remains such as published in studies with individuals who are established (long-term) vegetarians compared to omnivorous.
Health Status and Individual Care Needs of Disabled Elderly at Home in Different Types of Care
Authors: Tang Qi , Yuan Min , Wu Wenhui , Wu Huanyun , Wang Cao , Chen Gang , Li Chengyue , Lu Jun
Published: September 2022

For the disabled, paying attention to their health status is the starting point to discovering their survival problems, while meeting their care needs is the end point to solving their survival problems. As the country with the largest number of disabled elderly in the world, how to ensure this group could obtain appropriate home care is a major public health issue facing China. Thus, we conducted a cross-sectional study from October to December 2020 to explore the basic characteristics and health status of disabled elderly in different types of care who are living at home in 37 streets in Shanghai, as well as the individual care needs and its relevance. We observed the significant differences in the number of diagnoses (p = 0.03), smoking (p = 0.009), drinking (p = 0.016), exercise (p = 0.001), activity of daily living (p < 0.0001), and the quality of life (p < 0.0001) across care types. The care needs of the disabled elderly are diversified, of which a vast majority of them have not been fully guaranteed. The urgent need for improving the identification accuracy of care needs of disabled elderly, as well as the development of elaborate and personalized care programs for them, is needed.
Protection Motivation Status and Factors Influencing Risk Reduction Measures among the Flood-Prone Households in Bangladesh
Authors: Ansari Md. Sazzad , Warner Jeroen , Sukhwani Vibhas , Shaw Rajib
Published: September 2022

Bangladesh, a low-lying deltaic country, experiences recurrent floods. To reduce the subsequent losses and damages, self-preparedness measures are imperative. In that context, the present study attempted to assess the flood protection motivation status of local flood-prone households through the evaluation of threat and coping capacities, as well as the identification of the factors that influence preparedness actions. Using Protection Motivation Theory (PMT), this study employed a mixed-method approach at three different flood-prone locations in Bangladesh: (1) Type 1 settlement, an area with ‘hard (flood embankment)’ flood risk reduction measures; (2) Type 2 settlement, without any risk reduction measure; (3) Type 3 settlement, with ‘soft’ measures put in place as part of NGO-led disaster risk reduction interventions. The study findings revealed a comparatively higher protection motivation status among the respondents living in the Type 3 settlement, in terms of evaluating the flood risk and capacity to take flood preparedness measures. The correlation analysis further illustrated that the factors of the perceived probability and severity of flooding, coping capacity, previous flood experience, reliance on NGO interventions, and gender status had an influence on the protection motivation of flood-prone households. Remarkably, no such influence was found for socio-economic factors such as education and income. It is hoped that the study findings can support the future decision-making process for designing preparedness interventions for communities in flood-prone areas.
Source Identification and Superposition Effect of Heavy Metals (HMs) in Agricultural Soils at a High Geological Background Area of Karst: A Case Study in a Typical Watershed
Authors: Zhang Qiuye , Liu Hongyan , Liu Fang , Ju Xianhang , Dinis Faustino , Yu Enjiang , Yu Zhi
Published: September 2022

Exogenous sources and the superposition effect of HMs in agricultural soils made the idenfication of sources complicated in a karst area. Here, a typical watershed, a research unit of the karst area, was chosen as the study area. The smaller-scale study of watersheds allowed us to obtain more precise results and to guide local pollution control. In this study, sources of HMs in agricultural soil were traced by a CMB model. Superposition effects were studied by spatial analysis of HMs and enrichment factor (EF) and chemical fraction analysis. The average concentrations of Cd, Pb, Cr, Cu, Ni and Zn in surface soils were 8.71, 333, 154, 51.7, 61.5 and 676 mg∙kg−1, respectively, which exceeded their corresponding background values. The main sources of Cd, Pb and Zn in agricultural soil were rock weathering, atmospheric deposition and livestock manure, and their contributions were 47.7%, 31.0% and 21.2% for Cd; 7.63%, 78.7% and 13.4% for Pb; and 17.0%, 52.3% and 28.1% for Zn. Cr mainly derived from atmospheric deposition (73.8%) and rock weathering (20.0%). Cu and Ni mainly came from livestock manure (81.3%) and weathering (87.5%), respectively, whereas contributions of pesticides and fertilizers were relatively limited (no more than 1.04%). Cd, Pb, Zn and Cu were easily enriched in surface soils near the surrounding pollution sources, whereas Cr and Ni were easily enriched in the high-terrain area, where there was less of an impact of anthropogenic activities. The superposition of exogenous sources caused accumulation of Cd, Pb and Zn in topsoil, contaminated the subsoil through leaching and improved bioavailability of Cd and Pb, causing high ecological risk for agricultural production. Therefore, Cd and Pb should be paid more attention in future pollution control.
Concentration of Selected Macronutrients and Toxic Elements in the Blood in Relation to Pain Severity and Hydrogen Magnetic Resonance Spectroscopy in People with Osteoarthritis of the Spine
Authors: Jakoniuk Marta , Kochanowicz Jan , Lankau Agnieszka , Wilkiel Marianna , Socha Katarzyna
Published: September 2022

Macronutrients and toxic elements may play an important role in the pathogenesis of osteoarthritis of the spine. The objective of this study was to evaluate the relationship between the concentrations of Ca, Mg, Pb, Cd and Hg in blood with the results of hydrogen magnetic resonance spectroscopy and the severity of pain. Patients with osteoarthritis of the spine (n = 90) and control subjects (n = 40) were studied. The concentrations of mineral components in blood were determined by atomic absorption spectrometry (ASA). Spinal pain severity was assessed using the Visual Analog Scale (VAS). Hydrogen magnetic resonance spectroscopy (1H-MRS) was used to determine the fat/water ratio in the bodies of L1, L5 and the L4/5 intervertebral disc. The median concentration of Mg in the serum of subjects with spinal degenerative disease was significantly lower (p < 0.001) than that in healthy subjects. The median concentration of Cd in the blood of subjects with osteoarthritis of the spine was significantly higher (p < 0.05) than that in the control group. Significantly lower (p < 0.05) median molar ratios of Ca to Cd and Pb as well as Mg to Pb and Cd were observed among patients with osteoarthritis of the spine. Significant differences (p < 0.05) were observed in the value of the fat/water ratio in selected spinal structures, depending on normal or abnormal serum Ca and Mg concentrations. The study showed some abnormal macronutrient concentrations, as well as disturbed ratios of beneficial elements to toxic elements in the blood of people with osteoarthritis of the spine.
The Thermal Influence of an Electromagnetic Field with a Radio Frequency Depending on the Type of Electrode Used
Authors: Bryś Kamil , Grabarek Beniamin Oskar , Król Piotr , Staszkiewicz Rafał , Wierzbik-Strońska Magdalena , Król Tomasz
Published: September 2022

Diathermy is a method used in physiotherapy based on obtaining an increase in temperature by supplying energy from the electromagnetic field to the tissues. The aim of this retrospective work, based on the data included in a medical documentation, was to assess the dynamics of temperature changes on the body surface after the application of a high-frequency electromagnetic field depending on the type of electrode used. In order to generate a radio frequency electromagnetic field, an INDIBA ACTIV® CT9 was used. In order to measure the temperature, an HT-17 thermovision camera was used, enabling measurements within the range of −20 to 300 °C, with an accuracy of ±2% or 2 °C. The participants consisted of 30 healthy subjects (15 women and 15 men) who were physiotherapy students in the Faculty of Public Health in the Silesian Medical University in Katowice, Poland; they were divided into two comparative groups (A and B). It was found that the differences between the groups were not significant in the measurements carried out before using the electrode (p = 0.84; Mann–Whitney U test). On the other hand, at 0, 5 and 15 min, statistically significant differences were noted in the tissue temperature between the groups, depending on the electrode used (p = 0.00; Mann–Whitney U test). Based on the obtained results, it can be concluded that with the extension of the observation time, the tissue temperature increased (for Group A, Me 30.40 °C vs. 34.90 °C; for Group B, Me 30.70 °C vs. 35.20 °C). Our study confirmed that the use of both a capacitive and resistive electrode during treatment with the use of a high-frequency electromagnetic field statistically significantly increased the surface temperature of the area to which the therapy was applied. The results of the study can be used in clinical practice by physiotherapists to optimize the conditions of therapy.
Carbon Emission Factors Identification and Measurement Model Construction for Railway Construction Projects
Authors: Hu Xiaodong , Zhang Ximing , Dong Lei , Li Hujun , He Zheng , Chen Huihua
Published: September 2022

Carbon emissions have become a focus of political and academic concern in the global community since the launch of the Kyoto Protocol. As the largest carbon emitter, China has committed to reaching the carbon peak by 2030 and carbon neutrality by 2060 in the 75th United Nations High-level Meeting. The transport sector needs to be deeply decarbonized in China to achieve this goal. Previous studies have shown that the carbon emissions of the railway sector are small compared to highways, waterways, and civil aviation. However, these studies only consider the operation stage and do not consider the carbon emissions caused by large-scale railway infrastructure construction during the construction stage. As an essential source of carbon emissions and the focus of emissions reduction, the carbon emission of railway construction projects (RCPs) is in urgent need of relevant research. Based on a systematic literature review (SLR), this paper sorts out the carbon emission factors (CEFs) related to RCPs; combines semi-structured expert interviews to clarify the carbon emissions measurement boundary of RCPs; modifies and calibrates CEFs; constructs the carbon emission measurement model of RCPs including building material production stage, building material transportation stage, and construction stage; and conducts empirical analysis to validate carbon emission factors and measurement models. This study effectively complements the theoretical research on CEFs and measurement models in the construction stage of railway engineering and contributes to guiding the construction of low-carbon railways practically.
The Renaissance of the Vaginal Hysterectomy—A Due Act
Authors: Stark Michael , Malvasi Antonio , Mynbaev Ospan , Tinelli Andrea
Published: September 2022

For many years, vaginal and abdominal hysterectomies were part of the routine procedures in many departments. Both of them lost their priority due to the introduction of endoscopy and robotic surgery. The disappearing abdominal hysterectomy is certainly reasonable, but the decline of using vaginal hysterectomy seems not to be justified, and it is an optimal example of the recent emergence of the Natural Orifice Surgery discipline. A modified method for vaginal hysterectomy is presented in order to encourage gynecologists to reconsider vaginal hysterectomy as a valid method. This method is the outcome of critical analyses of different vaginal hysterectomy methods. It is simple, reasonable, only ten steps, easy to learn, perform and teach, and proven to be a shorter operation with minimal blood loss and reduced need for analgesics when compared to the traditional way. Endoscopy or robotic surgery is not available everywhere. Therefore, it is important that gynecologists in low-resource settings be familiar with this simple method.
Physical Activity in Centenarians beyond Cut-Point-Based Accelerometer Metrics
Authors: Hernández-Vicente Adrián , Marín-Puyalto Jorge , Pueyo Esther , Vicente-Rodríguez Germán , Garatachea Nuria
Published: September 2022

This study described and compared physical activity (PA) characteristics at the end of the human lifespan using conventional cut-point-based versus cut-point-free accelerometer metrics. Eighteen institutionalized centenarians (101.5 ± 2.1 years, 72.2% female, 89% frail) wore the wrist GENEActiv accelerometer for 7 days. Conventional metrics, such as time spent in light-intensity PA (LiPA) and moderate-to-vigorous intensity PA (MVPA) were calculated according to published cut-points for adults and older adults. The following cut-point-free metrics were evaluated: average acceleration, intensity gradient and Mx metrics. Depending on the cut-point, centenarians accumulated a median of 15–132 min/day of LiPA and 3–15 min/day of MVPA. The average acceleration was 9.2 mg [Q1: 6.7 mg–Q3: 12.6 mg] and the intensity gradient was −3.19 [−3.34–−3.12]. The distribution of Z-values revealed positive skew for MVPA, indicating a potential floor effect, whereas the skew magnitude was attenuated for cut-point-free metrics such as intensity gradient or M5. However, both cut-point-based and cut-point-free metrics were similarly positively associated with functional independence, cognitive and physical capacities. This is the first time that PA has been described in centenarians using cut-point-free metrics. Our results suggest that new analytical approaches could overcome cut-point limitations when studying the oldest-old. Future studies using these new cut-point-free PA metrics are warranted to provide more complete and comparable information across groups and populations.
Perception of Realism and Acquisition of Clinical Skills in Simulated Pediatric Dentistry Scenarios
Authors: Bartolomé Villar Begoña , Real Benlloch Irene , De la Hoz Calvo Ana , Coro-Montanet Gleyvis
Published: September 2022

Simulation, depending on the modality and fidelity of the scenarios, is an important resource for clinical teaching and achievement of learning outcomes in dentistry. The objectives of this study were to compare the degree of realism perceived by students and teachers in a simulated scenario, and to assess the level of competence acquired by the students. Method: In the Pediatric Dentistry course, eight clinical scenarios were carried out, each one using a modified Erler Zimmer child simulator (handmade), a professional actress and two students (dentist and assistant) on the same pediatric dentistry case consisting of a pulp abscess in tooth 8.5. A total of 114 students in the 4th year of dentistry studies participated in the pediatric dentistry course. Questionnaires with Likert-type answers were elaborated to evaluate the educational intervention, applying them before and after the simulation. Results: The realism best valued by the students was that of the simulated participant and the worst that of the manikin, the latter being strongly related to the realism of the office. It was observed that students’ perception of clinical competence increased as the overall realism of the scenario increased (p-value = 0.00576). Conclusion: This research suggests that the creation of scenarios using handmade mannequins and simulated participants achieves a high level of realism, increasing the level of clinical competence perceived by dental students.