bluuebunny/crossref_metadata_2025 huggingface dataset:
ЭКОЛОГИЧЕСКАЯ КУЛЬТУРА НАРОДОВ ПОВОЛЖЬЯ В ИСТОРИЧЕСКИХ, ЭТНОГРАФИЧЕСКИХ И ФИЛОСОФСКИХ ИССЛЕДОВАНИЯХ ХIX–XXI ВВ.
Authors: Lepeshkina Larisa Yurevna , Nurova Oksana Gennad’evna
Published: February 2019

Цель. Целью данной статьи является анализ исторических, этнографических и философских материалов об экологической культуре народов Поволжья, что необходимо для определения сущности последней.Метод или методология проведения работы. В статье используются классические методы научного исследования: сравнительно-исторический, логический, ретроспективный, проблемно-хронологический и др. Кроме того, в исследовании находит отражение такой методологический прием, как критика источников об экологических взглядах народов Поволжья. По мысли М. Хайдеггера, данный метод включает «весь комплекс разыскания, сопоставления, проверки, оценки, хранения и истолкования источников». Критикуя различные текстовые источники по конкретной проблеме, исследователь занимает диалогическую позицию по отношению к их авторам, что позволяет ему стремиться к более объективным выводам.Результаты. Процесс изучения экологической культуры Поволжского региона можно разделить на три периода: этнографический – XIX – первая четверть XX вв.; технократический – 1930–1960-е гг.; экоориентированный – 1970–2000-е гг. Выделение обозначенных периодов обусловлено социальными и политическими преобразованиями, происходившие в России и, как следствие, повлиявшие на характер научных исследований Поволжья.Область применения результатов. Обращение к истории изучения экологической культуры народов Поволжья позволит систематизировать сведения о роли человека в региональной экосистеме.
«ОСМНИЧЕЕ» И «ОСМЕННИК» В СРЕДНЕВЕКОВОЙ РУСИ: К ВОПРОСУ О КОНСТРУИРОВАНИИ ПОНЯТИЙ В РОССИЙСКОЙ ИСТОРИЧЕСКОЙ НАУКЕ XIX ВЕКА
Authors: Zavyalov Dmitry Anatolyevich
Published: February 2019

Цель. Статья посвящена истории конструирования понятий «осмничее» и «осменник» в русской исторической науке XIX в. В современной историографии содержание этих понятий является предметом дискуссии. Средневековая терминология таможенного дела являлась предметом изучения, по крайней мере, четырех поколений русских историков XIX в. (Н.М. Карамзин; Ю.А. Гагемейстер; Д.А. Толстой, Е.Г. Осокин, И.Д. Беляев, С.М. Соловьев; В.О. Ключевский, В.И. Сергеевич, С.А. Шумаков). Автор ставит целью выявить этапы и оценить исследовательские подходы конструирования исторических понятий, соответствующие им приемы, связанные с именами историков разных поколений.Метод или методология проведения работы. Характер данных, которыми располагали историки XIX в. при конструировании понятий «осмничее» и «осменник» привел их к необходимости выдвижения гипотез и систем гипотез, которые восполняли недостающие в источниках звенья объяснения. При оценке убедительности аргументации, лежащей в основе реконструкции понятий, необходимо отличать прямые показания источника от гипотез, основанных на эмпирическом материале источников и дающих убедительное и простое объяснение используемым показаниям, и, наконец, от догадок, т.е. предположений о факте, который мог происходить. В основу исследования положен историко-сравнительный метод.Результаты. Автор выявил и реконструировал применяемые историками приемы построения гипотез, и основанных на них догадок, которые со временем превратились в «исторические факты». Конструирование содержания понятий «осмничее» и «осменник» от поколения к поколению историков все более отдалялось от эмпирических данных источников, и все более основывалось на историографической традиции. Выявленный нами механизм конструирования понятий «осмничее» и «осменник», и составляющие его приемы характеризуют определенный этап позитивистской исторической науки в России.Область применения результатов. Результаты исследования могут быть применены в сфере преподавания истории таможенного дела и таможенной политики России, экономической истории, истории налогообложения.
ИНФОРМИРОВАННОЕ СОГЛАСИЕ ПАЦИЕНТА В СОВЕТСКОЙ СИСТЕМЕ ЗДРАВООХРАНЕНИЯ: ОТ ЭТИЧЕСКОЙ ТЕОРИИ К МЕДИЦИНСКОЙ ПРАКТИКЕ
Authors: Pyzhova Olesya Vladimirovna , Chaltseva Tatyana Aleksandrovna
Published: February 2019

Цель. В статье авторы ставят своей задачей проследить процесс трансформации информированного добровольного согласия пациента на медицинское вмешательство из этической теории в правовую практику в отечественной системе здравоохранения советского периода, поскольку гармония универсальных ценностей и правовых норм может одновременно регулировать не только поведение человека в рамках профессиональной этики, но и развитие медицинской науки.Метод и методология. Для изучения данной проблемы применялся диалектический и сравнительно-исторический методы исследования.Результаты. В ходе проведенного анализа внедрения в медицинскую практику теории информированного согласия на дискуссионной основе в общественных и медицинских кругах, а также на основе рассмотрения нормативно-правовых норм, регулировавших взаимоотношения врач-пациент в отечественной медицине XX века, авторы пришли к выводу что, получив первый опыт правового регулирования в СССР, практика согласия пациента на медицинское вмешательство в современной России приведена в соответствие с международными стандартами.Область применения результатов. Результаты исследования могут найти применение не только в области биоэтики, медицинского права, истории медицины и права в медицинских и юридических вузах в процессе обучения, но и стать основой отдельного исследования по изучению и совершенствованию нормативно-правовой базы информированного добровольного согласия пациента в условиях развития современной системы здравоохранения.
ИСТОКИ И СТАНОВЛЕНИЕ КАТЕГОРИИ «РАЗУМ» В ФИЛОСОФИИ
Authors: Volokhova Natalia Vladimirovna
Published: February 2019

Цель. Цель статьи – определение новых подходов и способов философского исследования категории «разум» в процессе его исторического формирования.Осуществление этой цели предполагает решение ряда взаимосвязанных задач: выделение и философская характеристика основных механизмов и этапов развития рациональности; выявление тенденций постановки и решения проблемы взаимоотношения разума в историко-философском процессе и жизнедеятельности человека.Научная новизна исследования заключается в выявлении развития категории «разум» как основополагающего начала в истории философской мысли и динамической составляющей непрерывного творческого мышления.Метод и методология проведения работы. Основу исследования составляет сравнительно-исторический метод и общенаучные методы аналогии, индукции и дедукции. Также применяется метод категориально-логической реконструкции, дополненный методом герменевтического анализа.Результаты. В статье обоснована мысль о системообразующем характере категории «разум» и включенности его в различные сферы человеческой деятельности. Раскрыто культурно-историческое и научно обоснованное дефинирование понятия «разум» и его содержание.Область применения результатов. Итоги исследования могут быть использованы при преподавании философии и социологии, а также в целях определения межпредметных связей между науками.
Queer subjectivities within political scenes: Traumatic relations, exposed vulnerabilities
Authors: Marinoudi Soula
Published: February 2019

This article examines the lives of queer people as performed in the biographies of ten interlocutors who participated in the queer political scene during the decade 2000–10. In recent years, a wide range of queer/feminist subjectivities, groups and spaces have emerged within collective social movements in Greece. These new approaches to radical feminism and queer life-forms often convey a sense of discontinuity with the recent past, as queer voices have been marginalized in the anti-authoritarian and the radical leftist political scene until recently. I argue that the anti-authoritarian and leftist political space in and around the various social grassroots movements constituted – in their own right – disciplinary fields as well as gender-constructing mechanisms. Gendered subjectivities, either entirely excluded or included on restrictive terms, exposed the limits of the political body. In this article, I explore how these new queer contexts can work through the traumas out of which they have emerged, and I argue that the emergence of a queer political scene in Greece signals a shift from passionate attachments to new modes of relationality. These new modes of relating expose vulnerabilities and emerge as negotiations of intimacy between the self and the other.
Critically queer and haunted: Greek identity, crisiscapes and doing queer history in the present
Authors: Papanikolaou Dimitris
Published: February 2019

How can one do the history of Modern Greek homosexuality at the present moment, in a country where intersectional precarity, neo-liberal control and proliferating austerity measures ensure that rights and political demands are in jeopardy? How can we historicise the ways in which ethnonationalism and neoconservative rhetoric create a phobic atmosphere, at the very moment when sexual and gender difference become more pronounced and are finally supported by institutional frameworks? This article offers an overview of the major milestones in Greek LGBTQI+ political representation as well as of recent attempts to articulate a Modern Greek queer history. Taking its cue from the shaming campaign against a cross-dressed man found cruising in the outskirts of Athens in 2016 and an analysis of the influential film Strella: A Woman’s Way (2009), it argues that we need to develop a new model of doing queer history in the present. Such a model will be both sensitive to the fluidity and historical challenge of queer emergence, but also remain ready to dwell on long histories of disavowal, institutionalized homophobia and suppression.
Bodies of truth: The terrible beauty of queer performance
Authors: Sampatakakis George
Published: February 2019

This piece examines five recent performances from Greece in an attempt to map both their interventions and contributions to the development of Greek queer aesthetics. It provides a chart of this relatively unknown performative landscape and explains how the queering process works in constructing queer ‘freaks’, cultural mourning and a new iconography of Greekness.
Comics and the slaughterhouse: Alberto Breccia and the neighbourhood of Mataderos
Authors: Scorer James
Published: February 2019

In this article, I explore the way that Alberto Breccia, one of Latin America’s most important comics artists, engages with the history and cityscape of the neighbourhood of Mataderos in Buenos Aires, Argentina. I focus on two of his comics set in this meat-packing district: the series Un tal Daneri (1974–77), written by Carlos Trillo, and the short-story ‘El aire’ (1976), written by Guillermo Saccomanno. Created during a period of increasing political violence, I analyse how these works express the material practice of animal slaughter as well as the slaughterhouse’s potent political symbolism. In particular I argue that the highly material, embodied techniques that Breccia uses, including cuts with blades, paper tears and collage, present Mataderos as an assemblage where human, animal and non-human fuse together. They also remind us of the material labour processes that underpin both these images and the neighbourhood itself. As a result, I suggest, these works both suggest an alternative to the dichotomy of civilization and barbarism that has dominated the Argentine political and urban imaginary, and also demonstrate how artistic practice can be used to embody the materiality of marginal bodies and spaces.
Demanding the city: Traces of the UN 50 protests in San Francisco
Authors: Garnand Jeff
Published: February 2019

Events of collective action pass into and then fade from the memory of cities, some leaving little trace in the casual historical archive. Do these events haunt the city as memories, imperfect, yellowing with age, long after the physical traces are gone? Using a mix of methods – urban observation, interview, and autoethnography – I returned in 2018 to the site of several of the actions I was a participant in for the 50th anniversary of the signing of the UN charter in San Francisco in 1995, interrogating the possibility that my presence would haunt the city of a very different present. The city of July 1995 was there, a spectral presence in the sunny world of capital that relentlessly but incompletely bleaches out the traces of its shadow, resistance. The conditions that produced those resistances have only become more pressing, the need for ghosts more urgent in a city that increasingly looks to its future without engaging its pasts.
Is forensic architecture the new muralism of the Mexican state? A reflection on racialized violence and the construction of Mexican identity
Authors: Harp Tania Osorio
Published: February 2019

In Mexico, the art of historical representation from the last 100 years has influenced and been influenced by the way we understand ourselves as Mexicans. The racial divisions of our society and the racialized state violence have been part of this process of representation. To me, the arts as a medium and mediator for the state’s incessant project of racializing indigenous peoples have intentionally overshadowed racial differences as part of the state’s political discourse. This article shows this relationship by taking as examples two case studies: Forensic Architecture’s exhibition at the Museo Universitario de Arte Contemporáneo (MUAC) in Mexico City, which portrays the brutal disappearance of 43 students in Ayotzinapa, Guerrero in 2014, and Diego Rivera’s mural The History of Mexico, commissioned in 1929 by the federal government, located today in the National Palace of Mexico City. Legacies of colonial past, such as racial segregation and oppression, and the influence of international ideas of modernization, liberalism and economic progress in Post-Revolutionary Mexico can be located in the material forms of representation of these two narratives. By re-problematizing the virtual spaces they represent, and the physical spaces they occupy or come from, my research points out a new layer of hidden racialized violence in the processes of construction of new and old historical narratives.
Gay desert modern: Sexuality, architecture and indigeneity in Palm Springs, California
Authors: Lenc Xander
Published: February 2019

While many authors have argued that queerness can interrupt hegemonic conceptions of time, less attention has been paid to the role of queer temporality in settlercolonialism. This article looks to Palm Springs, California, where largely white and gay architecture preservationists have been forced to reckon with the fact that many of the city’s celebrated Mid-Century Modernist buildings belong to a local Native American tribe with an ambiguous relationship with modern architecture preservation. I argue that the domestic arrangements of time and space among gay architecture preservationists constitute a radical break from heteronormative spatialtemporality, even as they sustain settler-colonial conceptions of indigenous time.
The Predictive Value of Phadiatop Paediatric in the Determination of Atopy in Allergic Diseases in Children
Authors: Harsono Ariyanto , Santosa Gunadi , S. Makmuri M.
Published: February 2019

We obtained 28 patients with asthma bronchiole in this study. The presumptive diagnosis of allergy was made on the basis of history and physical examination. The positive result of the skin test to inhalant extracts and positive history of inhalant allergy add a confirmatory evidence in the diagnosis of inhalant allergy. The diagnosis of food allergy was judged by positive result in the provocation test. This study provided 15 patients with food allergy and 13 patients with food and inhalant allergy. House dust a1Jd mites were the most prevalent positive result in the skin test. While in the provocation test, egg ·and milk were found as the most prevalent food causing symptoms of allergy. The skin test predicted the atopy with an efficiency of 53.5%, While Phadiatop Paediatric predicted the atopy with an efficiency of 82.1 %. We concluded, as a screening procedure in allergy, the Phadiatop Paediatric is better than the skin test. Nevertheless the skin test has its superiority in the development of logical environmental controls and as a guide to immunotherapy in inhalant allergy.
Risk Factors of Infantile Diarrhea (A Case-Control Study)
Authors: Lubis Iskandar Z.
Published: February 2019

From March thru April 1990 an unmatched case-control study had been conducted at the pediatric out-patient Clinic of Dr. Pirngadi Hospital Medan to assess risk factors of infantile diarrhea. The  study population were infants, aged younger than 21 months. The mothers of the infants were interviewed, using structured questionnaires.

Sample size, calculated by means of formula, with 95 % level of confidence, 90 % power of study, 50% estimated proportion of exposure in the control-group and 2.0 estimated odds ratio, was 121.

All infants with diarrhea were included in the case-group until a total number of 124 infants were reached. One control, an infant without diarrhea, was taken for each case from the nearest sequence of attendance after the case. A total of 20 risk factors were tested. Exposure was indicated from the last day before illness.

Computerized statistical analysis was performed to calculate odds ratio, 95 % confidence interval and two tailed significance testing for qualitative dichotomic data by means of Chi square test.

A total of nine factors were confirmed as risk factors of infantile diarrhea i.e mothers age than 20 years, working mother, not cleaning nipple before suckling the baby bottle feeding, having only one nursing botlle/teat, not ready for use nursing bottle/teat, giving left over supplementary food without reheating, no band-washing before giving supplementary food and malnutrition.

The result of this study can be emphasized in health education, especially in diarrheal disease control of infancy; Further well-designed studies are needed.
The Etiology of Nosocomial Infections in Pediatric Patients at the Department of Child Health, School of Medicine Padjadjaran University Hasan Sadikin General Hospital, Bandung
Authors: Garna Herry
Published: February 2019

Tbe distribution of pathogens causing nosocomial gastroenteritis was E. coli (69.2%), Salmonella sp (23.1%), rotavirns (6.4%) and Shigella sp (1.3%) . Klebsiella pneumoniae seemed to be the pathogen most frequently associated with nosocomial skin infections (26. 7%), followed by Enterobacter aerogenes (20.0%), E. coli, Ps. Aeruginosa and S. aureus, each in 13.3% and others 03.4%). Salmonella sp was the pathogen most frequently associated with nosocomial bacteremia (20.2%), followed by Klebsiella sp 07.9%), S. a/bus 04.3%), Enterobacter sp 01.9%), Pseudomonas sp (9.5%), S. aureus (9.5%) and others (16. 7%). In nosocomial urinary tract infections, the result was E. coli (32.9%), Klebsiella pneumoniae (20.5%), Enterobacter sp 03. 7%), Citrobacter diversus (6.8%) and others (26.1%).

In general, E. coli was the most frequently reported pathogens ( 42.0%), followed by Salmonella sp 07.1%), Klebsiella sp (10.2%), Citrobacter sp (7.2%), S. a/bus (4.5%), Pseudomonas sp (4.2%), S. aureus (3.6%) and others 01.2%), respectively.
Conjunctival Diphtheria
Authors: Pasaribu Syahrir
Published: February 2019

Three cases of conjunctival diphteria in 3 siblings of one family with the ages of 7 months, 6 and 8 years bad been reported. These children bad never obtained complete D1P immunization, one of them bad been once immunized with D1P.

General signs encountered were conjunctival hyperemia, ocular secretion and palpebral edema.

A relationship between length of ailment with appearance of clinical symptom and severity of the disease was noted.

Myocarditis as a complication was found in one case. Treatment in this series consisted of intravenous anti diphtheria serum (ADS) and intramuscular procain penicillin.
Polymorphisms associated with type 1 diabetes mellitus
Authors: Jaya Rachman Indra , Zettyana Yenni Riska , Bakri Achirul , Yuwono Yuwono , Aditiawati Aditiawati
Published: February 2019

Background Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. The genetic factors involved consist of at least five vulnerability genes:  HLA, INS, CTLA-4, PTPN22, and IL2RA/CD25.

Objective To investigate for associations of PTPN22-1123 G>C SNP and CTLA-4 +49A/G polymorphisms with T1DM.

Methods Case and control groups underwent CTLA-4 +49A/G gene examination from June to December 2017, using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis.

Results The study population consisted of 30 T1DM patients and 30 healthy subjects with no family history of diabetes or autoimmune diseases. With regards to the PTPN22-1123 G>C SNP, significantly more subjects with T1DM had the GC genotype than the GG genotype (OR 7.64; 95%CI 1.48 to 39.29; P=0.007). For the CTLA-4 +49A/G polymorphism, although the total number of G alleles in the case group was more than that  of  the control group  (OR 2.286; 95%CI 0.804 to 6.945; P=0.118), there were no significant relationships between the frequency of G alleles (P=0.248) and genotypes GG or AG (P=0.293) with the incidence of T1DM. However, the PTPN22-1123 G>C SNP had a significantly positive association with T1DM, and may be considered as a risk factor for T1DM. In contrast, the CTLA-4 +49A/G polymorphism was not recognized as a risk susceptibility factor for T1DM.

Conclusion These study confirms an association between PTPN22-1123 G>C SNP and T1DM, but no significant association between CTLA-4 +49A/G polymorphism and T1DM.
Hunter syndrome with hyperthyroidism: a 16 month follow-up reprt
Authors: Alfina Din , Prawirohartono Endy Paryanto , Naning Roni , Nurani Neti
Published: February 2019

Mucopolysaccharidosis (MPS) is a rare genetic disorder caused by a deficiency in the activity of lysosomal enzymes required for glycosaminoglycan (GAG) degradation. An accumulation of GAG in many organs results in progressive cellular damage, and clinically results in joint stiffness, airway and cardiac as well as, mental and hearing impairments. Incidence of MPS was reportedly 2.04 per 100,000 live births, but varies depending on type and region. In Taiwan, MPS type II was the most prevalent MPS, with an incidence of 1.07 per 100,000 live births.1 MPS is generally inherited in an autosomal recessive pattern, with the exception of MPS II, which is X-linked recessive.2 There are seven types of MPS (MPS I, II, III, IV, VI, VII, and IX), based on enzyme deficits.3 The types of MPS with their enzyme deficiencies are listed in Table 1.

Mucopolysaccharidosis shows wide clinical heterogenity, and is, therefore, difficult to diagnose. Skeletal involvement in MPS include coarse face, loss of joint range of motion, restricted mobility, and slowed growth leading to short stature. Other signs and symptoms include vision and hearing loss, recurrent respiratory infections, obstructive sleep apnea, hepatosplenomegaly, umbilical and inguinal hernia, hydrocephalus, spinal cord compression, and cognitive impairment.2,4 Patients with suspected MPS should have urinary GAG laboratory testing and enzyme activity assays in tissue (blood or fibroblasts). Urinary elevation of GAG, as compared with GAG levels expected in age-matched normal subjects, is the first diagnostic approach. The definitive specific diagnosis for MPS is based on enzyme activity assays from cultured fibroblasts, leukocytes, plasma, or serum.2,5,6 The MPS patients require multidiciplinary subspeciality management, including ENT, orthopedics, cardiology, pulmonary, growth and development, and physiotherapy. Specific treatments for MPS are hematopoietic stem cell transplantation (HSCT) and enzyme-replacement therapy (ERT) with recombinant human enzymes for MPS I, II, and VI.3,6,7,8 Life expectancies in MPS may vary among types, but generally are markedly reduced. Patients with MPS III and VII and severe forms of MPS I and MPS II have mental retardation. Patients with MPS II usually survive until only the second decade of life, with respiratory failure as the leading cause of death (56%), followed by cardiac failure (18%).9,10
Manifestation of Graves’ disease, resulting from radiosurgical treatment of acromegaly, in a patient with panhypopituitarism
Authors: Astafyeva Ludmila I. , Kalinin Pavel L. , Kienia Tatyana A. , Fadeyev Valentin V.
Published: February 2019

Cases of thyrotoxicosis associated with a previous case of secondary hypothyroidism are extremely rare. This article presents a rare clinical case of Graves disease manifestation in a patient with secondary hypothyroidism after radiosurgical treatment of acromegaly. A 38-year old woman presented with acromegaly and endo-supra-laterosellar pituitary adenoma. After non-radical removal of the pituitary adenoma, radiosurgical treatment of the of the residual tissue of the pituitary tumor in the cavernous sinus area was performed. After 14 months of radiation therapy, the acromegaly was in remission; after 24 months of radiation therapy, panhypopituitarism developed (secondary hypothyroidism, adrenal insufficiency, hypogonadism, and growth hormone deficiency). Furthermore, 1.5 years after the panhypopituitarism was diagnosed, the manifestation of Graves disease was also noted, requiring thyrostatic and radioactive iodine treatments.
Diagnostic criteria for secondary hypothyroidism are low levels of the thyroid hormones free T4 and free T3, with a reduced, normal or slightly elevated level of thyroid stimulating hormone (TSH). The criterion for the development of thyrotoxicosis in the context of the secondary hypothyroidism was the persistent increase in the level of free T4 despite adequate drug therapy with levothyroxine. In the case report, the patients diagnosis of Graves disease was confirmed by the presence of a high level of antibodies to the TSH receptor.
Prevalence of anabolic androgenic steroid use, its effect on the male pituitary-gonadal axis, and the possibility of reproductive rehabilitation
Authors: Lykhonosov Mykola P. , Babenko Alina Yu.
Published: February 2019

The purpose of this review is to assess the prevalence of AA steroid use, to identify the steroids that are used, and to present the negative effects of AA steroids on the human body while describing the mechanisms of their actions on the male reproductive system. The review highlights the diagnostic features of steroid-induced hypogonadism, and assesses the effectiveness of various drugs in the reproductive rehabilitation of patients who cease taking AA steroids. Emphasis is placed on the feasibility and effectiveness of various drug treatments in the context of post cycle therapy (PCT), which seeks to stabilize and restore normal hormonal function. All this data is necessary for the development of modern treatment algorithms for steroid-induced hypogonadism in men.
Long-term Survival of Patient with Ampulla of Vater Metastasis of Renal Cell Carcinoma
Authors: Ignatavicius Povilas , Lizdenis Paulius , Pranys Darius , Gulbinas Antanas , Pundzius Juozas , Barauskas Giedrius
Published: February 2019

Ampulla of Vater metastases from renal cell carcinoma are rare. The time between detection of the primary tumour and its metastasis may extend to years. Management should be aggressive, since the prognosis of renal cell carcinoma is unpredictable and curative surgery of metastases may extend patient survival and even lead to definite cure. Herein we report a case of long-term survival after successful surgical treatment of a renal cell carcinoma metastasis to the ampulla of Vater. A 62-year-old man with a history of renal cell carcinoma in the left kidney underwent a successful left nephrectomy. Eight months later duodenoscopy showed a tumour at the site of papilla of Vater. Biopsy confirmed the diagnosis of carcinoma. Contrast enhanced computer tomography scan verified the periampullary mass, dilatation of the pancreatic and the common bile duct. No radiological signs of either local advancement or distant metastases were present. Pylorus-preserving pancreatoduodenectomy with lymphadenectomy was performed. Pathology report disclosed metastatic lesions in the papilla of Vater from the clear cell carcinoma of the kidney. The postoperative course was uneventful, and the patient lived for 14 years after pancreatoduodenectomy and, following thorough investigations, was free from local and systemic recurrence. Pancreatoduodenectomy can provide long-term survival in selected cases with solitary papilla of Vater metastasis from renal cell carcinoma. Favourable long-term survival rates suggest that these patients should be considered candidates for pancreatoduodenectomy if experienced pancreatic surgeon is available and no other metastases are found.
Generic constructions of PoRs from codes and instantiations
Authors: Lavauzelle Julien , Levy-dit-Vehel Françoise
Published: February 2019

In this paper, we show how to construct – from any linear code – a Proof of Retrievability (

𝖯𝗈𝖱

{\mathsf{PoR}}

) which features very low computation complexity on both the client (

𝖵𝖾𝗋𝗂𝖿𝗂𝖾𝗋

{\mathsf{Verifier}}

) and the server (

𝖯𝗋𝗈𝗏𝖾𝗋

{\mathsf{Prover}}

) sides, as well as small client storage (typically 512 bits).
We adapt the security model initiated
by Juels and Kaliski
[PoRs: Proofs of retrievability for large files,
Proceedings of the 2007 ACM Conference on Computer and Communications Security—CCS 2007,
ACM, New York 2007, 584–597]
to fit into the framework
of Paterson, Stinson and Upadhyay
[A coding theory foundation for the analysis of general unconditionally secure proof-of-retrievability schemes for cloud storage,
J. Math. Cryptol. 7 2013, 3, 183–216],
from which our construction evolves.
We thus provide a rigorous treatment of the security of our generic design; more precisely, we sharply bound the extraction failure of our protocol according to this security model.
Next we instantiate our formal construction with codes built from tensor-products as well as with Reed–Muller codes and lifted codes,
yielding

𝖯𝗈𝖱

{\mathsf{PoR}}

s with moderate communication complexity and (server) storage overhead, in addition to the aforementioned features.
Combined Effect of ASE Noise and SRS Induced Crosstalk on the BER Performance of a Single Span WDM System with Raman Amplifier Using Heterodyne Coherent Detection
Authors: Tithi F.H. , Majumder S.P.
Published: February 2019

Analysis is presented to evaluate numerically the combined effect of amplified spontaneous emission (ASE) and stimulated Raman scattering (SRS) on the bit error rate performance of a WDM transmission system with Raman amplifier using heterodyne receiver. The results are compared with those for a WDM system reported with direct detection receiver for different system parameters. It is observed that coherent heterodyne system is less affected by the crosstalk due to combined effect of ASE and SRS compared to direct detection. It is noticed that allowable transmission distance is 170 km, and 166 km of WDM channels for 8, and 16, respectively, when coherent heterodyne receiver is and with pump power of 10 mW and channel bandwidth of 12.5 GHz. The corresponding transmission distance is 60 km and 10 km, respectively, for direct detection system already reported.
Different Graded Refractive Index Fiber Profiles Design for the Control of Losses and Dispersion Effects
Authors: Rashed Ahmed Nabih Zaki , Satheesh Kumar S. , Tabbour Mohammed Salah F. , Sundararajan T.V.P. , Maheswar R.
Published: February 2019

This paper has presented the basic infrastructure of different multilayer graded index fiber profiles design. The optimum graded refractive index fiber profile design for the control of total Losses and dispersion effects are considered. The trade-off between different refractive index fiber profiles is realized in order to achieve loss and dispersion effects management. It is evident that the proposed first optical fiber has presented lower dispersion and splice loss than other proposed fibers. As well as the proposed third optical fiber outlines lower effective mode field diameter and micro bending loss than other proposed fibers. Dominant mode, cutoff wavelength and international telecommunication union-telecommunication (ITU-T) values for each fiber are examined based on finite difference method.
An Adenosine A2AReceptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis
Authors: Asaoka Nozomi , Nishitani Naoya , Kinoshita Haruko , Nagai Yuma , Hatakama Hikari , Nagayasu Kazuki , Shirakawa Hisashi , Nakagawa Takayuki , Kaneko Shuji
Published: February 2019

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by the repeated rise of concerns (obsessions) and repetitive unwanted behavior (compulsions). Although selective serotonin reuptake inhibitors (SSRIs) is the first-choice drug, response rates to SSRI treatment vary between symptom dimensions. In this study, to find a therapeutic target for SSRI-resilient OCD symptoms, we evaluated treatment responses of quinpirole (QNP) sensitization-induced OCD-related behaviors in mice. SSRI administration rescued the cognitive inflexibility, as well as hyperactivity in the lateral orbitofrontal cortex (lOFC), while no improvement was observed for the repetitive behavior. D2receptor signaling in the central striatum (CS) was involved in SSRI-resistant repetitive behavior. An adenosine A2Aantagonist, istradefylline, which rescued abnormal excitatory synaptic function in the CS indirect pathway medium spiny neurons (MSNs) of sensitized mice, alleviated both of the QNP-induced abnormal behaviors with only short-term administration. These results provide a new insight into therapeutic strategies for SSRI-resistant OCD symptoms and indicate the potential of A2Aantagonists as a rapid-acting anti-OCD drug.
Optogenetic Stimulation of the M2 Cortex Reverts Motor Dysfunction in a Mouse Model of Parkinson's Disease
Authors: Magno Luiz Alexandre Viana , Tenza-Ferrer Helia , Collodetti Mélcar , Aguiar Matheus Felipe Guimarães , Rodrigues Ana Paula Carneiro , da Silva Rodrigo Souza , Silva Joice do Prado , Nicolau Nycolle Ferreira , Rosa Daniela Valadão Freitas , Birbrair Alexander , Miranda Débora Marques , Romano-Silva Marco Aurélio
Published: February 2019

Neuromodulation of deep brain structures (deep brain stimulation) is the current surgical procedure for treatment of Parkinson's disease (PD). Less studied is the stimulation of cortical motor areas to treat PD symptoms, although also known to alleviate motor disturbances in PD. We were able to show that optogenetic activation of secondary (M2) motor cortex improves motor functions in dopamine-depleted male mice. The stimulated M2 cortex harbors glutamatergic pyramidal neurons that project to subcortical structures, critically involved in motor control, and makes synaptic contacts with dopaminergic neurons. Strikingly, optogenetic activation of M2 neurons or axons into the dorsomedial striatum increases striatal levels of dopamine and evokes locomotor activity. We found that dopamine neurotransmission sensitizes the locomotor behavior elicited by activation of M2 neurons. Furthermore, combination of intranigral infusion of glutamatergic antagonists and circuit specific optogenetic stimulation revealed that behavioral response depended on the activity of M2 neurons projecting to SNc. Interestingly, repeated M2 stimulation combined withl-DOPA treatment produced an unanticipated improvement in working memory performance, which was absent in control mice underl-DOPA treatment only. Therefore, the M2-basal ganglia circuit is critical for the assembly of the motor and cognitive function, and this study demonstrates a therapeutic mechanism for cortical stimulation in PD that involves recruitment of long-range glutamatergic projection neurons.

SIGNIFICANCE STATEMENTSome patients with Parkinson's disease are offered treatment through surgery, which consists of delivering electrical current to regions deep within the brain. This study shows that stimulation of an area located on the brain surface, known as the secondary motor cortex, can also reverse movement disorders in mice. Authors have used a brain stimulation technique called optogenetics, which allowed targeting a specific type of surface neuron that communicates with the deep part of the brain involved in movement control. The study also shows that a combination of this stimulation with drug treatment might be useful to treat memory impairment, a kind of cognitive problem in Parkinson's disease.
Application of PICCO During Anesthesia of Patients Undergoing Transcatheter Ventricular Isolation Plasty Due to Left Ventricular Aneurysm
Authors: Xu Guiping , Zhang Yuxuan , Wang Quansheng , Su Tao , Mei Jing , Li Ruixuan , Yan Qiang
Published: February 2019

Introduction: Left ventricular aneurysm is a common complication type of myocardial infarction. Percutaneous ventricular restoration (PVR) is a new and minimally invasive surgical method for left ventricular aneurysm. Due to its complication and high demand on the surgeon, careful cooperation of anesthesia work is of great significance for the successful implementation of the operation.
Case Presentation: During anesthesia, Pulse Index Continuous Cardiac Output (PICCO) not only monitors general hemodynamic parameters, but also displays parameters such as cardiac output, myocardial contractility, pre-cardiac load, etc., which provides important guidance for the anesthetic procedures.
Conclusions: This study aimed to explore the application of PICCO in the anesthesia of patients by analyzing the clinical anesthesia management of 3 cases of patients undergoing transcatheter ventricular partitioning restoration (TVPR) due to left ventricular aneurysm in the case of analysis.
Tradición clásica y utopía en La caída del águila, de Carlos Gagini
Authors: Herrera Valenciano Minor
Published: February 2019

Carlos Gagini plantea la construcción de un espacio utópico, la isla del Coco. La novela La caída del águila evoca, a partir de una lectura desde la tradición clásica, el mito de la Atlántida, ejemplo de espacio utópico en la Antigüedad. El presente trabajo establece y analiza la relación entre el mito atlántico, mencionado en los diálogos platónicos Critias y Timeo y la idea de espacio utópico desarrollado por el novelista costarricense.
Soumission: una fenomenología de la academia
Authors: Alfaro Vargas Roy
Published: February 2019

Se analiza la novela Soumission, de Michel Houellebecq, en relación con su personaje central François, para describir la dialéctica entre el hedonismo neoliberal y fenomenológico, y lo económico, en tanto crítica de la academia, en el contexto de la actual crisis del capitalismo. Asimismo, el análisis permite la elaboración de una poética realista-dialéctica relacionada con el extrañamiento cognitivo de la ciencia ficción y con el realismo de Balzac, Zola y Flaubert, para contrarrestar la política de lo imposible desarrollada en las narrativas innaturales y el novum tecnocrático.
Temperature dependence of decagonal quasicrystals heat capacity
Authors: Sukhova O. V. , Syrovatko Yu. V.
Published: February 2019

The heat capacity of decagonal quasicrystals of the Al–Co–Cu or Al–Co–Ni alloys was calculated at the temperatures of 600, 700, and 900 K in this work. The expression for the heat capacity of the quasicrystals was obtained based on the Debye model. For the quasicrystals, the linear “excessive” heat capacity is observed in the range of temperatures between 400 to 600 К which means the deviation from the 3R Dulong-Petit value. The heat capacity at a temperature of 900 К is about 28.4 J/mol К which is higher than the Dulong-Petit value (~ 25 J/mol К). The “excessive” heat capacity relates to the peculiarities in the decagonal quasicrystal anisotropy. These crystals are quasiperiodic in the x and y directions, and periodic in the z direction. As a result, there is a difference in the dispersive laws in the different directions. The Debye temperature values have essential influence on the temperature dependencies of the heat capacity of the decagonal quasicrystals. Thus, the higher the Debye temperature and the larger “excessive” heat capacity, the more stable are considered the quasicrystals exposed to the temperature effects.
Photoluminescence and EPR spectrum of ZnO:Mn nanocrystals
Authors: Kovalenko O. V. , Bulaniy M. F. , Vorovskiy V. Y. , Khmelenko O. V.
Published: February 2019

Nanocrystals of ZnO:Mn were obtained by ultrasonic spray pyrolysis and had dimensions of d ~ 36 nm. The changes of photoluminescence end EPR spectra of these nanocrystals in dependence of Mn admixture concentration ( 2–8 at. %) and also at heat treatment in air during 1 hour at T = 850 ̊C were investigated. It is shown that under short-term (7–10 s) nonequilibrium conditions of ZnO:Mn nanocrystals forming, they consist of a nuclens and shell surface, in which, predominantly, the Mn admixture is concentrated. After annealing, the Mn admixture diffuses into the nucleus of a nanocrystal.
Influence of heat treatment on photoluminescence spectra in ZnS:Mn crystals with hexagonal structure
Authors: Kovalenko O. V. , Khmelenko O. V. , Plakhtii Ye. G.
Published: February 2019

It has been investigated the influence of heat treatment with the following temperins on the integral photoluminescence spectra and on the individual bands of this spectra. It has been showed the correlation between the changes of intensity of photoluminescence individual bands and real structure of crystal, controlled with the help of EPR method. The basic changes of photoluminescence and structural properties have threshold nature. They begin to show up at temperature of annealing T > 650o С. The maximum intensity of integral photoluminescence spectrum was observed in the region of phase transition crystal structure of zinc sulphide.
The features of the use of the waveguide radiators in smart antenna systems
Authors: Morozov V. M. , Magro V. I.
Published: February 2019

The features of the use of finite waveguide antenna arrays in the structure of modern smart antenna systems are considered. The paper deals with the problem of diffraction of an electromagnetic wave on a finite waveguide antenna array scanning in the E-plane. Antenna array consists of five radiating elements. The open ends of the waveguides are surrounded by a metal screen. The resonator coupling region was chosen as matching elements. The solution of the problem is carried out by the integral equation method on the basis of the selection of overlapping regions. The problem reduces to solving the Fredholm integral equation of the second kind. An array of infinitely thin plates and that of waveguides with a finite wall thickness are considered. The main regularities for choosing the optimal geometric dimensions of the antenna array are established. Studies were carried out for arrays with a number of elements from five to fifteen. The analysis of edge effects in the final antenna array is carried out. It is shown that the introduction of a resonator region into a five-element lattice makes it possible to expand the sector of the radiation angles and avoid the effect of blinding. It is shown that this statement is valid not only for five-element lattices, but also for arrays with a large number of radiating elements. The radiation patterns are calculated. The  coefficients of mutual coupling in an array with five elements are investigated. General recommendations for choosing optimal sizes of the resonator coupling region of radiators are considered.
COPPER TRIFLATE CATALYZED BAEYER- VILLIGER OXIDATION OF KETONES
Authors: Duc Dau Xuan , Nguyet Nguyen Thi
Published: February 2019

A simple, efficient and eco-friendly method for Baeyer-Villiger oxidation reaction has been developed. The reaction employed m-CPBA as the oxidant with Cu(OTf)2 catalyst and was carried out in CH2Cl2 at room temperature. Nine lactones and ester were obtained in excellent yield (85-94%). Furthermore, the catalyst could be reused twice without considerable loss in activity.
CONSTITUENTS AND INHIBITORY EFFECT ON HUMAN PATHOGENIC BACTERIA OF THE ROOTS OF SCUTELLARIA BAICALENSIS
Authors: Le Duc Long , Nguyen Huu Tung , Nguyen Thi Thom , Choi Gyung Ja , Vu Dinh Hoang , Le Dang Quang
Published: February 2019

Abstract-HCTN_16Methanol extract of the roots of Scutellaria baicalensis effectively inhibited the bacterial growth of human pathogenic bacteria Staphylococcus aureus ATCC 6538, Bacillus cereus ATCC 21768 and Bacillus subtilis ATCC 6633 at MICs of 2,000 µg/mL. n-Hexane, ethyl acetate and aqueous residues were prepared by successively partitioning the methanol extract with n-hexane and ethyl acetate. Among them, only ethyl acetate layer showed antibiotic effect; whereas n-hexane and aqueous layers were inactive against tested bacteria. The ethyl acetate residue was fractionated by silica gel column chromatography to afford three flavonoids and an oligosaccharide. Their chemical structures were elucidated as wogonin (SB1), baicalein (SB4), baicalin (SB5) and tetrasaccharide (SB10) on the basis of the analysis of NMR and MS spectroscopic data. The isolates were evaluated for in vitro inhibitory effect against human pathogenic bacteria using micro dilution bioassay method. Baicalein (SB4) showed a broad-spectrum inhibition against various human pathogenic bacteria. In particular, it was found to potently inhibit S. aureus ATCC 6538 and B. cereus ATCC 21768 with MICs of 9.5 and 38 µg/mL, respectively. The study results demonstrated antibiotic effect of the extracts from the roots of S. baicalensis and characterization of compounds isolated from the plant materials.
ANTIOXIDANT POTENTIAL OF FIVE COMPOUNDS EXTRACT FROM THE MARINE FUNGUS ASPERGILLUS FLOCCULOSUS BY DFT METHOD: HAT AND SET MECHANISM.
Authors: Trang Phan Thi Thu , Van Tran Thi Thanh , Chinh Ngo Thi , Chinh Phan Thi Hoai , Quang Dao Duy
Published: February 2019

Antioxidant potential of five compounds include ochraceopone F (1), aspertetranone D (2), cycloechinulin (3), wasabidienone E (4) and mactanamide (5) in the extracts from marine fungus Aspergillus flocculosus in Nha Trang was investigated by computational chemistry methods. All calculations were performed at the theoretical level M05-2X/6-311++G(d, p)//M05-2X/6-31+G(d) in the gas phase. The physicochemical properties such as bond dissociation energies (BDE), ionization energies (IE), electron affinity (EA) characterizing HAT (Hydrogen atom transfer) and SET (Single electronic transfer) antioxidant mechanisms were calculated.As a result, the H-atom donating ability of the studies compounds increases in the descending order of BDE value (1) > (2) > (3) > (4) » (5). Wherein the compounds (4) and (5) represent as the most potential antioxidant with the lowest BDE in the gas phase being 74.9 and 75.1 kcal/ mol. Moreover, the electronic donating ability of the compounds increases as function of the descending order of IE value (2) > (1) > (5) > (3) > (4). And the electron accepting abitlity decreases in decreasing EA value (4) > (3) > (2) > (5) > (1). Compound (4) (wasabidienone E) has the smallest IE value of 6.56 eV and has the largest EA value of 2.33 eV.
A VARIATIONAL MODE DECOMPOSITION BASED APPROACH FOR CARDIOPULMONARY RESUSCITATION ESTIMATION AND ASSESSMENT
Authors: Thao Tran Thi , Truong Pham Van
Published: February 2019

Cardiac arrests remain leading causes of deaths for thousands of people annually. One of the most common methods for cardiac arrest treatment is cardiopulmonary resuscitation (CPR) that provides chest compressions. It has been shown that the quality of chest compression is considered as one of key indicators for assessment of CPR performance. In this paper, we present an approach for CPR quality evaluation using ECG contaminated with CPR artifact and thoracic impedance. The proposed approach contains two key steps: First, the CPR artifact signal is estimated via variational mode decomposition (VMD) and a mode selection algorithm based on mode’s frequency and frequency of thoracic impedance signal. In the second step, CPR parameters performed on the estimated CPR signals are computed and compared with those derived by reference CPR. The proposed approach is applied for a dataset including patients presenting with asystole, ventricular tachycardia, and pulseless electrical activity. Quantitative results validate the performance of the proposed approach for CPR quality assessment.