bluuebunny/crossref_metadata_2025 huggingface dataset:
An Assessment of the Expertise Required of Workers, in the Context of Their Capacity to Cope With Libya’s Fourth Industrial Revolution
Authors: Mohamad E , Balrwein H.T Saeid , Rahman M.A A , Azlan N.A. A., Nor , Rahman M.S Abd , Saptari A
Published: February 2022

The advent, of Libya‘s fourth industrial revolution (4IR), rendered the structure of the country‘s smart factories exceedingly intricate, vibrant and variable. Several investigators, in this domain, believe that the most significant factors, influencing the outcome of Libya‘s 4IR, are the skills gap and manpower development issues. In order for the 4IR to progress, it is crucial that more sophisticated capabilities be developed. This undertaking should begin with an assessment of the existing expertise of the stakeholders themselves (self-evaluation). The purpose of this exercise, is to identify the deficiency in skills, with regards to the skill sets, that are essential for the 4IR. This calls an evaluation of the stakeholders‘ degree of comprehension regarding the 4IR, and their willingness to involve themselves in this exercise. Stakeholders both within and beyond Libya‘s manufacturing division, should be taken into account for this evaluation. The main objective, of this study, is to ascertain the impact of 4IR, on the aspects of human labour and work organization. To achieve this objective, we opted for the quantitative method. A questionnaire was formulated to scrutinize every single detail in the manpower‘s supply chain, stretching from Libya‘s learning system to its workforce.
Penerapan Non Delay Schedule Dengan Mempertimbangkan Machine Availability Constraint untuk Meminimasi Makespan pada PT Autotech Perkasa Mandiri, Cikarang, Jawa Barat
Authors: Maukar Anastasia Lidya , Sosodoro Ineu Widaningsih , Setiady Stefanus
Published: February 2022

One of the efforts to increase production efficiency is by implementing the right scheduling. PT Autotech Perkasa Mandiri is the job shop production system. Currently implements a heuristic method with a priority dispatch rule, namely the Earliest Due Date (EDD). The EDD rule has the highest priority for the job with the earliest due date to be processed on a machine. This study is to purpose a more optimal scheduling by comparing the makespan of the current schedule with the proposed one. Previous research is the non delay schedule without considering machine availability constraints. In this study, machine availability constraints are taken into account, thus, they are more realistic when applied to the actual problem. The algorithm used is a non delay schedule with working time window (WT-NSA). Machine availability constraints that are taken into account are lunch-break hours (12: 00-13: 00) and shift changes (17: 00-08: 00). From the analysis, it is obtained that makespan from non delay schedule is 23 hours 6 minutes, while makespan from WT-NSA is 26 hours 6 minutes, and makespan from EDD schedule is 38 hours 54 minutes. Non-delay schedule has the smallest makespan, which is 23 hours 6 minutes, but WT-NSA is more realistic when applied to the real problem.
Perbaikan Kualitas Produk Kaos Sablon Berdasarkan Area Kerja Menggunakan New Seven Tools Dan 5S
Authors: Oemar Hirawati , Widianti Widya , Mulyati Dewi Shofi
Published: February 2022

CV. Bandung Mulia Konveksi is one of the clothing convection company located in Bandung which produces three types of products includes jackets, screen printing t-shirts and shirts. The products are produced by passing the same workstation namely the workstation of pattern, cutting, screen printing, and sewing. Based on data on the amount of production and data on the number of defective products in the last five years, CV. Bandung Mulia Konveksi can be seen that only screen printing t-shirts that have a percentage of disability outside the company's tolerance limit. Defects that occur on screen printing t-shirts can be known based on the work area. Quality improvement can be done using New Seven Tools to identify problems and 5S concepts for proposed improvements. The 5S checklist audit results and the giving of the 5S score on the conditions prior to the 5s applications a score of 20% is obtained, which means it is very bad. Whereas after the 5S implementation and the 5S audit checklist were carried out and the 5S score was given, the score increased to 62% which means good.
Aplikasi Sensor Passive Infra-Red (PIR) untuk Meningkatkan Keselamatan Pekerja pada Mesin-Mesin Produksi Industri
Authors: Simatupang Joni Welman , Sucipta Indra , Wibowo Azis , Kuncoro Kuncoro , Siringoringo Yosua
Published: February 2022

This research of literature study discusses about the function and application of infrared sensor-based motion detection devices for work safety on industrial cam machinery.This device was designed to assist the industry in preventing the work accidents that occur due to hazardous industrial machinery. The detector uses a PIR (Passive Infra-Red) sensor as a motion detector of the human limbs. On its application, PIR sensor is placed on a specific side of the machine. Then, the system will provide an automatic cut-off alarms on the machine when a person crosses the fabric area that has been detected by the sensor. It was expected that this way will protect the manpower from the occurrence of work accidents which are caused by dangerous industrial machines. With the implementation of this infrared sensor design, the analysis of hazardous machinery is becoming increased so that this infrared sensor based working security system is growing and easier for shaping in many designs.
Investigation of The Awareness Level in Malaysia’s Manufacturing Industries on the Implementation of Industry 4.0
Authors: Mohamad Effendi , Abd Rahman M.S , Abdul Rahman A.A , Mohamad N , Nor Azlan N.A.A , Saptari Adi
Published: February 2022

In this study, the researchers aimed to investigate the awareness of the Malaysian manufacturing industries with regards to the implementation of the Industry 4.0 concept and also determine its levels. Different sectors of the Malaysian manufacturing sector like the Government Link Companies (GLCs), Small and Medium-scale Enterprises (SMEs), and other national or Multinational Corporations (MNCs) were included in this study. The researchers applied a survey-based research methodology and their sample size consisted of 91 Malaysian corporations. The participants in this study comprised of the managers and employees, as company representatives, and they were asked to complete the questionnaire and participate in the interview. The results of the survey showed that around 50.5% of respondents were aware and familiar with the Industry 4.0 regulations. Also, according to the survey results, the awareness regarding the Industry 4.0 regulations was mainly due to the foreign sectors including the multinational corporations like the electrical and electronic industries which contained several advanced assets and increased productivity. These results were very helpful for further research, especially for creating a future framework that could assimilate the ideas related to Industry 4.0 amongst the various other Malaysian industries belonging to the manufacturing sector.
Pengembangan Teknologi Audio-Visual dalam Pembelajaran Bahasa Arab
Authors: Raudatussolihah Baiq
Published: February 2022

This study aims to explain the types of audio-visual and their advantages and disadvantages in learning Arabic, and the use of audio-visual technology in learning Arabic. The method used in this research is qualitative research with a descriptive approach and its implementation is through library research and literature review. Audio-visual technology is a medium that educators can use in learning Arabic that is easy to understand and fun. Moreover, it is supported by technological developments that can be used as audio-visual media in the development of Arabic learning. Educators can also direct students to visit internet sites that discuss Arabic studies according to the theme and level of students.
Manajemen Asuhan Kebidanan Intranatal pada Ny. M dengan Serotinus
Authors: Sarfina Cici , Sundari Sundari , Batara Andi Surahman
Published: February 2022

Menurut organisasi dunia WHO pada tahun 2013 sebanyak 58.500 perempuan meninggal. 99% kematian akibat masalah persalinan atau kelahiran di negara–negara berkembang merupakan angka tertinggi dengan 450 kematian ibu per 100.0000 kelahiran hidup. Jika dibandingkan rasio kematian ibu di 9 negara dan 51 negara maju hal tersebut disebabkan perdarahan 40-50%, infeksi 20-30%, pre-eklamsia 20-30%. Data dari medical record RSUD Labuang Baji Makassar Januari sampai Desember 2019 sekitar 556 ibu yang bersalin dengan angka kejadian serotinus sebanyak 31 kasus. Jenis penelitian ini bersifat deskriptif dengan menggunakan metode studi kasus Manajemen Kebidanan yang terdiri dari 7 langkah Varney, yaitu : Pengumpulan Data Dasar, Interpretasi Data Dasar, Diagnosa Potensial, Tindakan Segera, Menyusun Rencana, Melaksanakan Secara Menyeluruh Asuhan Kebidanan serta Mengevaluasi Keberhasilannya. Asuhan Kebidanan pada ibu bersalin Ny. ‘’M’’  Kala I, fase laten berlangsung (1-3 jam), 3 jam kemudian ibu pada fase aktif deselerasi dengan pembukaan serviks 10 cm. Waktu proses persalinan dari kala I sampai kala IV berlangsung (6 jam 5 menit), keadaan umum Ibu dan Bayi dalam batas normal sampai dipindahkan ke ruang nifas. penelitian ini, bidan dapat menerapkan manajemen asuhan kebidanan sesuai dengan prioritas masalah pasien secara menyeluruh sehingga tindakan yang akan dilakukan bidan dapat dipertanggung jawabkan berdasarkan metode ilmiah.

 

Kata kunci : persalinan;serotinus
Monitoreo de colonias de mono aullador rojo (Alouatta Seniculus) en la antigua PTAR de Valledupar, Colombia
Authors: Cañate González Abid Silvestre , Martínez Rodríguez Lorena Catalina , Lacouture Quiroz Beatriz Eugenia , Bayona Pérez Yesica Fernanda
Published: February 2022

Esta investigación presenta los resultados obtenidos en el monitoreo de la población de Monos aulladores (Alouatta seniculus) presentes en el area de la Clausurada Planta de Tratamiento de Aguas Residuales (PTAR) El Tarullal en el barrio Amaneceres del Valle en la ciudad de Valledupar, su caracterización, medidas para su protección, estado general de la zona y recomendaciones, buscando generar conciencia en la ciudadanía, entidades municipales y ambientales sobre la conservación de esta especie y su hábitat, hogar de esta y muchas especies silvestres más.
Prototype Pembelajaran Pemanfaatan Energi Baru Terbarukan Berbasis Energi Surya
Authors: Samsurizal Samsurizal , Azzahra Septiannissa , Christiono Chistiono , Fikri Miftahul , Azis Hastuti , Yogianto Agus
Published: February 2022

The use of renewable energy (EBT) is increasing to achieve the target of 23% by 2025. There needs to be a variety of preparations in welcoming the transition of fossil-based energy to renewable energy. One of them is by improving the quality of human resources that excel in developing the use of renewable energy in Indonesia. Through the Electrical Engineering PkM Team IT-PLN had the opportunity to provide counseling or education to the academic community of MA Al-Khairiyah Rancaranji. The activity is in the form of learning the installation of solar power plant components and the utilization of solar energy in the form of prototype portable plts. The learning improved students' understanding of renewable energy and was able to assemble photovoltaic system components into prototype portable plts with a capacity of 100 WP. Then the tool is tested using a lamp load of 9 watts to find out the amount of current and voltage produced. From this activity, it can be known that the students of MA Al-Khairiyah Rancaranji are very enthusiastic in knowing about renewable energy and can apply it in the surrounding environment.
Pemanfaatan Aplikasi Gamifikasi Wordwall Di Era Pandemi Covid-19 Untuk Meningkatkan Proses Pembelajaran Daring
Authors: Putra Syahrizal Dwi , Aryani Diah , Ariessanti Hani Dewi
Published: February 2022

Gamification applications for online learning are something that needs to be socialized at this time, especially during the pandemic to improve the learning process. SDIT Insan Rabbani / Integrated Islamic School (SIT) Insan Rabbani is an Islamic educational institution that is oriented towards character building for its students. To improve the online learning process in this pandemic era, the school wants to use the concept of gamification in the online learning process. Besides that, teachers also want ways to build school learning content that can increase student engagement for online learning, especially during the current pandemic. So the abdimas team provided a solution by offering counseling on the use of gamification using a wordwall. Wordwall was chosen so that teachers can easily understand the concept of gamification and create various quiz/evaluation templates that are owned by wordwall. The expected target is for teachers to understand concepts and use gamification to increase student involvement in the online learning process.
On the so-called curative verbs in Finnish
Authors: Pennanen Esko V.
Published: February 2022

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Karelian Sprachbund? Theoretical basis of the study of Russian/Baltic-Finnic contacts
Authors: Sarhimaa Anneli
Published: February 2022

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Die delabialisierende Wirkung der anlautenden und inlautenden labialen Konsonanten im Urpermischen
Authors: Rédei Károly
Published: February 2022

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Flujos de plasma hidrodinámicos y magnetohidrodinámicos. Parte III
Authors: Rotstein Néstor Osvaldo , Bustelo Cancela Ignacio
Published: February 2022

En este artículo hallamos la expresión  general de la topología que el campo magnético adopta para poder  limitar las corrientes que se generan a lo largo de sus líneas en plasmas con resistividad no nula.  A los efectos de comparar con modelos de plasmas ideales asumimos componente azimutal de la fuerza de Lorentz nula.  Mostramos que la intensidad del campo magnético no depende del coeficiente de difusión, como sí lo hacen el campo eléctrico inducido y el flujo másico asociado. El desacople de las isosuperficies de flujo de masa y las superficies de flujo magnético constante hace que el problema matemático no sea ya de variables separables, pero mostramos las condiciones que deben cumplir la densidad de masa (que deja de ser esféricamente simétrica) y el campo de velocidades.
Evaluation of Weight Loss and Quality of Life in Morbidly Obese Patients Undergoing Y De Roux Gastric Bypass Surgery with Reduction Ring and Without Ring, After The First Year of Follow-Up
Authors: Franca Fabiana Tornincasa , de Almeida Gentile João Kleber , Migliore Renato , Bueno de Souza Pedro Marcos Santinho , Assef José César
Published: February 2022

Obesity is an epidemic disease in the modern world. The clinical therapies, when isolated, are not effective to weight loss and control in morbidly obese patients (BMI > 40 Kg/m²) in long term. Surgery is the only method proven effective to achieve these goals. The Gastric Bypass Roux-Y (RYGB) is the most commonly performed bariatric surgery in the world including Brazil and is considered the gold standard of bariatric procedures because of its effectiveness in losing and maintaining long term weight loss associated with lower complication rates. There is a discussion about the need of using the sylastic ring at the end of gastric pouch, when the RYGB surgery is done, surgery known as the Fobi-Capella, because the high incidence of complications related to the ring and the difficulty in the intake of solids. Today, many surgical teams perform Capella’s surgery without placement the ring, with the argument that weight loss is similar without the limitations and complications related to the ring. The proposal of this study is analyzing the need to use the ring in morbidly obese patients comparing the weight loss after one year and nutrition quality. Thus, we compared two groups of patients, first group submitted in 2009 to gastric bypass (RYGB with ring or Capella’s surgery) and the second group operated in 2010 (RYGB without ring), analyzing the results for weight loss and quality of life after 1 year elapsed from surgery through established questionnaires as BAROS and specific questionnaires on nutrition quality. Of the total 21 patients, 12 patients were submitted to RYGB with ring and the other 9 patients were submitted RYGB without placement of the ring. The surgery is aimed at weight loss and resolution of comorbidities associated with obesity. It is considered an effective surgical technique when weight loss is greater than 50% of the overweight in 75% of patients. The study showed that both types of surgery, with or without the ring, reach the objective. The study noted that patients submitted to RYGB with ring have an important restriction on the intake of meat, while the group submitted to RYGB surgery without the ring eat better foods rich in protein and has no postprandial vomiting, with a better-quality food. Regarding quality of life, we observe significant improvement in all variables in both groups without statistical difference.
Endoscopic Radiofrequency Ablation of Fistula in Ano (E-RaFisTura) in the Era of Surgical Innovation. A Serial Prospective Evaluation of 10 Patients
Authors: Xiarchos Anastasios , Tshijanu Fernand , Tsakpini Athanasia
Published: February 2022

Background: Fistula in-ano is an abnormal chronic infected tunnel (tract) between the rectum or the anal canal and perianal skin usually, with granulation tissue which connecting a primary orifice (internal) to a secondary one (external). This morbid antity represents a dilemma for both, patients and surgeon-proctologists because of postoperative issues occurrence such as fecal incontinence. The surgical management of this infectious condition has emerged nowadays, by emphasing new surgical techniques that preserve anal sphincter's integrity and functional. Over the last decade, numerous techniques sparing anal sphinters have gained popularity such as endoscopic approach (VAAFT), Laser, fibrin glue, transanal advancement flap repair [1,6]. In the same perspective,we are presenting in this paper, our preliminary outcomes of a combination of endoscopic approach (VAAFT) with Radifrequency Ablation of the fistula's tract that we nicknamed with the acronym of E-RaFisTura). Methods: We enrolled 10 males patients with anal fistula, age groupe 50-70 years, without any comorbidity in the term of diabetes mellitus, bowel inflammatory disease. Preoperatively each of them underwent a digital rectal examination, pelvic MRI, colonoscopy to rule out any concomitant abscess, Crohn's disease. Fleet enema, subcutaneus lower molecular weight heparin as well as intravenous broad spectrum antibiotic were administered an hour prior the surgical procedure. All patients were shifted to endoscopic surgical treatment of anal fistula (VAAFT) by using the fistuloscope of Piercarlo Meinero combined to the device of Fistura (Radiofrequency Ablation) with its probe 6-7 F (Figure 1 a,b,c). Then we visualized the fistula's tract and we seal it with radiofrequency thermocoagulation without damaging the anal sphincters by closing the internal opening with a suture node (Vicryl Rapid 3-0). Taxinomically, 2 patients had intersphincteric fistula, 3 transphincteric and the 5 others had submucosal anal fistula. Outcomes: We are inthe third month of follow up, none of the aboved mentioned patients has presented any postoperative issue excepting some local discomfort in immediate postoperative day, relieved with voltaren. Furthermore, the orificial wound healing is successful. Conclusion: Focused on our preliminary results, despite the small volume of patients, this combination of endoscopic and radiofrequency ablation can be regarded with optimism in selected patients. We will perform a powerful prospective study with a huge sample to have more accurate opinion. Bioethics Considerations: All enrolled patients had given their written consent prior. Furthermore,this surgical trial was approved by the Ethical commitee of Our Clinic.
Treating Parkinson Disease with Autologous Telomerase-Positive Stem Cells, Update 2021
Authors: Young Henry E. , Speight Mark O.
Published: February 2022

Parkinson disease (PD) is the second most common progressive neurodegenerative disorder that affects older adults. PD is characterized by a low level of dopamine being expressed in the striatum and a deterioration of dopaminergic neurons and associated neural networks in the substantia nigra of the midbrain. Current medical, surgical, and rehabilitative treatments for PD have long-term side effects and do not halt the progression of the disease. Stem cell therapies generating dopaminergic neurons from fetal brain tissue, human embryonic stem cells, human induced pluripotent stem cells, mesenchymal stem cells, human neural stem cells, direct reprogramming of somatic cells and direct reprogramming of stem cells by either gene editing, and/or gene transfer have elicited keen interest as to eventual therapeutics for Parkinson disease. Unfortunately, thus far, these experimental therapies have proved to be of limited therapeutic value in clinical trials. Using a neurotoxin-induced animal model of PD, transplantation of a naïve telomerase positive pluripotent stem cell clone demonstrated reconstitution of dopaminergic neurons and associated neural networks when stereotactically injected into neurotoxin-lesioned substantia nigra pars compactum of the ventral midbrain. Two IRB-approved clinical trials in small cohort studies (n=8 & n=4), with a combined sample size of n=12, demonstrated that intranasal infusion of autologous telomerase positive totipotent cells followed by intravenous infusion of telomerase positive pluripotent stem cells and mesodermal stem cells had a positive influence on patient symptomology with Parkinson’s Disease. No adverse effects were reported by any participant or their respective caregiver for the entire combined small cohort study (n=12). Taken together as a 2021 update of this on-going clinical study, 33% (n=4) showed moderate to no benefit of telomerase positive stem cell treatment by demonstrating a continued decline in symptoms after treatment; 33% (n=4) remained in stasis after the first month after treatment; and 33% (n=4) resolved their symptoms. The results suggest that autologous telomerase positive stem cells, TSCs, PSCs, and MesoSCs, are safe and efficacious (66%) to reduce the symptoms in participants with Parkinson’s disease.
Blunt Force Trauma-Induced Total Bilateral Visual Impairment of 13 Years Duration Treated with Autologous Telomerase-Positive Stem Cells
Authors: Young Henry E. , Speight Mark O.
Published: February 2022

Loss of visual acuity may result from genetics, cancer, metabolic disorders, trauma, or aging. Adult telomerase- positive totipotent stem cells have been identified in multiple species of animals, including humans. Characterization studies to identify differentiated cells utilized three clones of adult-derived totipotent stem cells (TSCs) and treated them with induction factors consisting of chemical mediators, human recombinant proteins and cell-specific exosomes. Results demonstrated that the TSC clones would form cells expressing phenotypic markers of the neural ectodermal lineage, e.g., ectodermal stem cells, ectodermal progenitor stem cells, neurons, ganglion cells, glial cells, and neural crest derivatives. Autologous TSCs were shown to partially restore function in clinical trial participants with Alzheimer’s disease, Parkinson’s disease, and Age-related Dry Macular Degeneration. It was hypothesized that following intranasal infusion, TSCs would migrate to areas associated with the visual pathway to repair and/or regenerate damaged and/or missing cells, thus restoring function. In this small cohort study (n=1), the presenting symptom for a 17-year-old female was total bilateral visual impairment (complete blindness) of 13-years duration, due to severe head trauma from an automobile accident at four years of age. Following her first TSC treatment, she could see indistinct black shapes on a background of a dark shade of gray. Following her second TSC treatment she could see background as a lighter shade of gray and a black square with slightly more distinct borders. No adverse effects were noted after either autologous TSC treatment. These results suggest that two treatments with TSCs were both safe and somewhat efficacious in helping to partially restore her ‘night’ vision.
Avaliação dos impactos do processo de desertificação no Seridó Ocidental a partir de indicadores biofísicos e sociais
Authors: Esteves Poliana Maria da Silva Valdevino , Cruz Fabiano Santiago
Published: February 2022

O processo de degradação das terras do semiárido está associado às vulnerabilidades ambientais e econômicas relacionadas a fatores de origem natural e principalmente antrópico. Historicamente a microrregião do Seridó Ocidental Paraibano teve a Caatinga como meio de subsistência e fonte de renda. A retirada abusiva da cobertura vegetal está ligada à presença de atividades econômicas exploratórias, como a agricultura, pecuária, cotonicultura e desde então a mineração. Estudos iniciados desde a década de 80 por Vasconcelos Sobrinho já apontava a microrregião como uma área de elevado risco de desertificação, posteriormente chamado de Núcleo de Desertificação devido às características naturais e as consequências de atividades antrópicas que devastam grandes espaços para pastagem retirando lenha e carvão para consumo próprio, assim como para olarias, panificadoras e outras finalidades econômicas energéticas. Esse trabalho faz o levantamento das características naturais (precipitação, clima, solo e relevo bem como da retirada da lenha e madeira para abastecimento local e de outras localidades) que favorecem a degradação ambiental e os processos que levam à desertificação.
Preliminary analysis of linear and angular kinetic parameters of the gait of individuals with cerebral palsy
Authors: Rodrigues Janaína de Oliveira , Sá Angela Abreu Rosa de , Freitas Deny Gomes , Naves Eduardo Lázaro Martins
Published: February 2022

Normal gait patterns allow the identification of the normal movement pattern, such as the gait of people with cerebral palsy. Paralympic classification systems aim to include the participation in sports of people with cerebral palsy, minimizing the impact of the injury on the result of the competition. In this context, this study aims to investigate, functionally, the linear and angular kinetic parameters of gait in individuals with cerebral palsy. 15 participants with cerebral palsy were classified into three groups according to the classification of the International Paralympic Committee: 1) T35- diplegic; 2) T36- athetoid ataxic; 3) T37- hemiplegic. For data acquisition, we used a motion capture system in 3 dimensions. The results showed significant differences between the three groups in some linear and angular gait variables, corroborating the qualitative classification process already used by the International Paralympics Committee. In addition, we identified the existence of people with different levels of cerebral palsy within a single functional class of International Paralympics Committee.  We found significant differences in some linear and angular gait variables among the classes T35, T36 e T37, which suggest "subgroups" inside each category, and this would prevent a athlete from competing on equal terms with the other competitors.
Green banana biomass (Musa sp.) as an ingredient in the development of pasta
Authors: Tinoco Layla Pereira do Nascimento , Oliveira Lorena de Sá , Augusta Ivanilda Maria , Barbosa Junior José Lucena , Barbosa Maria Ivone Martins Jacintho
Published: February 2022

Green banana biomass (GBB) can be used as a functional and technological ingredient in various food preparations, making them healthier and more nutritious. The aim of the present study was to determine the physicochemical compositions as well as color parameters of different GBB samples, and applying them to gnocchi pasta to determine the resulting technological and cooking properties. The bananas (‘BRS Platina, ‘Fhia 01,’ and ‘Fhia 18’) were grown in an area of the Agroecological Production Integrated System, in Seropédica-RJ, Brazil; the bananas were harvested unripe and pressured cooked to obtain their biomass. The pH values, total titratable acidity, total soluble solids, reducing sugars, moisture, ash, proteins, lipids, total starch, total energetic value (TEV), vitamin C, total phenolic compounds (TPC), minerals, and color were significantly different among the different GBB samples used. Each GBB showed different values of certain analyzed parameters; for instance, ‘BRS Platina’ presented low contents of total starch, lipids, TEV and high levels of vitamin C and TPC. The GBB ‘Fhia 01’presented the highest levels of moisture, proteins, and potassium. All GBBs provided good technological attributes (cooking time, weight increase, cooking loss, and volume increase) for the prepared gnocchi dough. Overall, the application of GBB as an ingredient in gnocchi formulation provided good technological quality and increased nutritional value, thus meeting the growing demand of the consumer market for products with greater health benefits.
URGENSI KOMUNIKASI MODEL STIMULUS ORGANISM RESPONSE (S-O-R) DALAM MENINGKATKAN KUALITAS PEMBELAJARAN
Authors: Rahmat abidin Andi , Abidin Mustika
Published: February 2022

Abstract: Communication in learning is a basic element that has a very urgent position and role in realizing the success of the educational process. Communication in learning can affect the achievement of the quality of education and of course can improve the quality of learning itself. The learning process cannot be separated from communication, therefore it is important for educators (teachers) to be skilled at communicating and understand the science and principles of effective communication in education, one of which is by applying the stimulus organism response model communication. In this paper, the author wants to analyze the urgency of the stimulus organism response (S-O-R) model of communication in improving the quality of learning. The author concludes that the communication of the stimulus organism response model is very important to be applied by the teacher because this communication is an action-reaction process so that verbal words, non-verbal cues, certain symbols will stimulate the communicant (students) to respond in a certain way. By implementing this communication, the message conveyed by the teacher can foster passion for the communicant so that the communicant quickly receives the message received and subsequently changes in knowledge, attitude and behavior so that this is an indicator of an increase in quality in learning.
Seasonal and spatial variability of Atlanto-Iberian pelagic fish diet with estimates of intraguild predation
Authors: Fonseca P , Silva AD , Angélico MM , Garrido S
Published: February 2022

The diets of 3 of the most abundant coastal pelagic fish species in the eastern Atlantic (sardine, anchovy and Atlantic chub mackerel) were investigated, including seasonal, geographical and ontogenetic variability of the diets. We also estimated the impact of cannibalism and intraguild predation on egg mortality, and a different method to evaluate egg mortality is proposed taking the spatial overlap of predators and eggs into account. Diet overlap occurred between the 3 pelagic species, which derive most of their dietary carbon from mesozooplankton prey. However, calanoid copepods were mostly important for anchovy and sardine, whereas the diet of the Atlantic chub mackerel also included crustacean eggs, nauplii, small copepodites and larger prey such as decapods. Sardine was the main predator of fish eggs (90% of all identified eggs), followed by Atlantic chub mackerel (8%) and anchovy (2%). Cannibalism by anchovies and sardines on their eggs was low (<10% of spawned eggs) for all areas and seasons. The impact of sardine predation on anchovy egg mortality was high (71% of the anchovy eggs spawned per day during the spring off northwestern Iberia) and may explain why anchovy abundance has only peaked in recent years, when sardine abundance was at its lowest level, highlighting the importance of taking an ecosystem approach to fisheries management into account. However, species-specific data of gastric evacuation rates and feeding durations are needed to obtain more accurate estimates of the impact of cannibalism and intraguild predation on egg mortality.
Absence of a Significant Interaction of Two Common NOS1 and 5-HTT Polymorphisms on Sensorimotor Gating in Humans
Authors: ROVNÝ R , MARKO M , MINÁRIK G , RIEČANSKÝ I
Published: February 2022

The neurotransmitter serotonin has been critically implicated in the pathogenesis of several mental disorders. The serotonin transporter (5-HTT) is a key regulator of serotonergic neurotransmission and its genetic variability is associated with increased risk of psychopathology. One well known polymorphic locus in the 5-HTT gene affecting its expression is a tandem repeat in the promoter region (5-HTTLPR). It has been reported that 5-HTT is functionally coupled with the neuronal nitric oxide synthase (NOS1 or nNOS), an enzyme catalyzing the production of nitric oxide (NO). We have previously demonstrated that a tandem repeat polymorphism in the promoter of NOS1 exon 1f (Ex1f-VNTR) is associated with sensorimotor gating, a marker of inhibitory processing and a well established endophenotype of several neuropsychiatric disorders. Here we investigated the combined genetic effects of NOS1 Ex1f-VNTR and 5-HTTLPR on sensorimotor gating, measured by prepulse inhibition (PPI) of the acoustic startle reflex, in 164 healthy adults. We found no evidence for the interaction between NOS1 Ex1f-VNTR and 5-HTTLPR on PPI. PPI was associated with NOS1 Ex1f-VNTR, but not 5-HTTLPR. Our data suggest that while NOS1 plays a role in sensorimotor gating, the nitrergic pathway of gating regulation does not involve the action of 5-HTT.
#VACHINA: How Politicians Help to Spread Disinformation About COVID-19 Vaccines
Authors: Recuero Raquel , Bonow Soares Felipe
Published: February 2022

This paper focuses on how Brazilian politicians helped to spread disinformation about Covid-19 vaccines, discussing legitimation strategies and actors that played a significant role on Twitter and Facebook. Based on data gathered through CrowdTangle and Twitter API, we selected the 250 most shared/retweeted posts for each dataset (n=500) and examined if they contained disinformation, who posted it, and what strategy was used to legitimize this discourse. Our findings indicate that politicians and hyperpartisan accounts have a key influence in validating the Brazilian president’s populist discourse through rationalization (pseudo-science) and denunciation (against the vaccine). The political frame also plays an important role in disinformation messages.
De Winter Wave with ST Segment Elevation Equivalent with Speech Disorder; A Case Report
Authors: Erdem Ahmet Burak , Tümer Miray
Published: February 2022

ABSTRACT
Acute coronary syndrome is a clinical condition that may require urgent coronary intervention. The most important is myocardial infarction with ST elevation. Emerging clinical studies now show equivalents of ST elevation myocardial infarction without ST elevation. The de Winter wave has been recognized as the equivalent of the ST-elevation myocardial infarction described since 2008.
A 71 year old male patient was admitted to our emergency deparment with a symptom of speech disorder and later angina. We also detected myocardial infarction with de Winter wave in the patient. In the coronary angiography of the patient, we demonstrated the presence of acute thrombus in the circumflex artery, which is much less common in the literature.
Early diagnosis is very important in this acute coronary syndrome that develops without ST elevation. We think that the speech disorder and feeling of worsening in our patient progressed as a result of a vital dystrhythmia that occured before coming to our emergency deparment. Widespread ischemic changes in magnetic resonance imaging in the flair phase may be caused by brain hypoperfusion due to this dysrhythmia. Coronary angiography should be planned for these patients.
The Artistic Heritage of Architect Vasily Stasov as a Reflection of the Main Trends in the Development of Russian Architecture from the Late 18th to the Mid-19th Century
Authors:   Saint Petersburg State University of Architecture and Civil Engineering, Zima Andrey G.
Published: February 2022

The article presents carried-out research work on the artistic heritage of Vasily Stasov (the buildings that identify to the greatest degree the architect’s stylistic techniques) as determining the main trends in the development of Russian architecture from the end of the 18th to the mid-19th century, namely, the “High Classicist” style, which was predominant during this period, and the sources of historicism. In order to minimize subjectivity when analyzing the evolution of Russian architecture following the main buildings designed by Vasily Stasov, the principle of this assessment was formed. Within the framework of the creative heritage of Vasily Stasov, research was made of: a complex of shopping malls, the interior of a palace (using the example of a ceremonial office), triumphal arches (gates) (four examples), a complex of stables (two examples), food warehouses (two examples), a complex of barracks, restoration work (by the example of a cathedral in an architectural ensemble), cathedrals (two examples) and a church, a tenement house, and a palace ensemble.
Viscoelasticity, Like Forces, Plays a Role in Mechanotransduction
Authors: Mierke Claudia Tanja
Published: February 2022

Viscoelasticity and its alteration in time and space has turned out to act as a key element in fundamental biological processes in living systems, such as morphogenesis and motility. Based on experimental and theoretical findings it can be proposed that viscoelasticity of cells, spheroids and tissues seems to be a collective characteristic that demands macromolecular, intracellular component and intercellular interactions. A major challenge is to couple the alterations in the macroscopic structural or material characteristics of cells, spheroids and tissues, such as cell and tissue phase transitions, to the microscopic interferences of their elements. Therefore, the biophysical technologies need to be improved, advanced and connected to classical biological assays. In this review, the viscoelastic nature of cytoskeletal, extracellular and cellular networks is presented and discussed. Viscoelasticity is conceptualized as a major contributor to cell migration and invasion and it is discussed whether it can serve as a biomarker for the cells’ migratory capacity in several biological contexts. It can be hypothesized that the statistical mechanics of intra- and extracellular networks may be applied in the future as a powerful tool to explore quantitatively the biomechanical foundation of viscoelasticity over a broad range of time and length scales. Finally, the importance of the cellular viscoelasticity is illustrated in identifying and characterizing multiple disorders, such as cancer, tissue injuries, acute or chronic inflammations or fibrotic diseases.
Serum Soluble ST2 Is a Valuable Prognostic Biomarker in Patients With Acute Heart Failure
Authors: Wang Zeyu , Pan Xin , Xu Hong , Wu You , Jia Xiaomin , Fang Yiling , Lu Yi , Xu Yawei , Zhang Ji , Su Yang
Published: February 2022

Background

This study aimed to investigate the clinical utility of different soluble suppression of tumorigenicity 2 (sST2) levels in assessing the severity and prognosis of patients with acute heart failure (AHF).

Methods

This was a prospective cohort study. Three hundred and thirty-one consecutively enrolled AHF patients from March 2018 to November 2019 were divided into 3 subgroups according to sST2 levels: T1 (1.15–7.70 ng/ml; N = 110), T2 (7.71–17.24 ng/ml; N = 111), and T3 (17.26–47.42 ng/ml; N = 110). The patients were followed up for a median period of 21.0 months for the development of the primary endpoint. Cox proportional hazards model was performed to evaluate the prognostic value of sST2 for the clinical outcomes.

Results

The mean age of patients was 69 years (range, 34–93 years), and 70.4% were male. During the follow-up period, 63 participants died. Patients with higher sST2 levels had lower left ventricular ejection fraction (correlation = −0.119, P = 0.031), and higher New York Heart Association classification (correlation = 0.443, P < 0.001) and N-terminal pro-B type natriuretic peptide (NT-proBNP) levels (correlation = 0.392, P < 0.001). Higher sST2 was also associated with creatinine, urea nitrogen, hemoglobin, and left ventricular mass index. Multivariate analysis revealed that sST2 (per log unit, hazard ratio: 2.174, 95% confidence interval [CI] 1.012–4.67, P = 0.047) and NT-proBNP (per log unit, HR 2.171, 95%CI 1.169–4.032, P < 0.001) were independent risk factors for the primary outcome in all patients with AHF.

Conclusion

sST2 can provide prognostic information in AHF. The higher the sST2 level in patients with AHF, the higher the incidence of cardiovascular death.
Uterine Cavity Irrigation With Office Hysteroscopy During Ovarian Stimulation for IVF: A Randomized Controlled Trial
Authors: Ghasemi Marzieh , Aleyasin Ashraf , Fatemi Human M. , Ghaemdoust Faezeh , Shahrakipour Mahnaz
Published: February 2022

Objective

This was a non-blinded randomized controlled study to evaluate whether endometrial irrigation via office hysteroscopy during the early follicular phase would lead to a higher level of live birth rates compared to no irrigation in the fresh embryo transfer cycle.

Method

The study was conducted in Tehran university of medical sciences from June 2015 to June 2016. women under the age of 40 with primary infertility without history of previous IVF/ICSI or hysteroscopic examination, were included. Controlled ovarian hyperstimulation was done. Hysteroscopy was performed in the early mid-follicular phase of a stimulation cycle (day 5-7) with a vaginoscopy approach and saline irrigation in hysteroscopy group. Embryo-transfer was done in the same cycle.

Results

228 patients completed their participation in the study. In the fresh cycle, clinical pregnancy rate was 46% in the hysteroscopy group and 40.43% in the control group. (p-value= 0.326, RR= 1.16 [95%CI: 0.862 to 1.56]). Live birth rate was 41.28% in the hysteroscopic group and 31.93% in the control group (p-value=0.143, RR= 1.293 [95%CI: 0.916 to 1.825]). For those patients having surplus cryopreserved embryos, after 2 months, a second embryo transfer was performed. The cumulative LBR was 44.05% in the hysteroscopic group and 32.25% in the control group (p-value=0.029, RR= 1.368 [95%CI: 1.031 to 1.815], RD= 11.9% [95%CI: 1.2% to 22.3%] and NNT= 8 [95%CI: 4 to 85]).

Conclusion

The current study clearly demonstrated a significantly higher cumulative live birth rate in the intervention group.

Clinical Trial Registration

[https://www.irct.ir/trial/19586], identifier IRCT2016011022795N2.
Effect of Acetazolamide and Zoledronate on Simulated High Altitude-Induced Bone Loss
Authors: Brent Mikkel Bo , Simonsen Ulf , Thomsen Jesper Skovhus , Brüel Annemarie
Published: February 2022

Exposure to hypobaric hypoxia at high altitude puts mountaineers at risk of acute mountain sickness. The carbonic anhydrase inhibitor acetazolamide is used to accelerate acclimatization, when it is not feasible to make a controlled and slow ascend. Studies in rodents have suggested that exposure to hypobaric hypoxia deteriorates bone integrity and reduces bone strength. The study investigated the effect of treatment with acetazolamide and the bisphosphonate, zoledronate, on the skeletal effects of exposure to hypobaric hypoxia. Eighty 16-week-old female RjOrl : SWISS mice were divided into five groups: 1. Baseline; 2. Normobaric; 3. Hypobaric hypoxia; 4. Hypobaric hypoxia + acetazolamide, and 5. Hypobaric hypoxia + zoledronate. Acetazolamide was administered in the drinking water (62 mg/kg/day) for four weeks, and zoledronate (100 μg/kg) was administered as a single subcutaneous injection at study start. Exposure to hypobaric hypoxia significantly increased lung wet weight and decreased femoral cortical thickness. Trabecular bone was spared from the detrimental effects of hypobaric hypoxia, although a trend towards reduced bone volume fraction was found at the L4 vertebral body. Treatment with acetazolamide did not have any negative skeletal effects, but could not mitigate the altitude-induced bone loss. Zoledronate was able to prevent the altitude-induced reduction in cortical thickness. In conclusion, simulated high altitude affected primarily cortical bone, whereas trabecular bone was spared. Only treatment with zoledronate prevented the altitude-induced cortical bone loss. The study provides preclinical support for future studies of zoledronate as a potential pharmacological countermeasure for altitude-related bone loss.
Theoretically Modified Optical Length Research on the Physical Boundary of the Double-Heterogeneous System
Authors: Lei Lou , Xiaoming Chai , Dong Yao , Lianjie Wang , Mancang Li , Liang Chen , Xiaoli Liu , Hongbo Zhang , Sinan Li , Xiao Tang , Nan Zhou
Published: February 2022

Because of the double-heterogeneity (DH), dispersed particle-type systems cannot be described by traditional neutronic programs, and the volumetric homogenization method (VHM) will bring reactivity calculation deviation because of ignoring the spatial self-shielding effect of the particles. In this article, the relationship between the reactivity calculation deviation and the optical length of dispersed particle-type fuel and different types of burnable poisons is analyzed. Also then, it was proposed that the influencing factors of reactivity calculation deviation can be integrated to a physical quantity named theoretically modified optical length containing the influencing factors mentioned earlier. In addition, the DH physical boundary has forward that, when the theoretically modified optical length is larger than 10−4, reactivity calculation deviation of volumetric homogenization method will be larger than 100 pcm, and the DH of the dispersed particle-type systems should be considered.
Slowing Deforestation in the Brazilian Amazon: Avoiding Legal Deforestation by Compensating Farmers and Ranchers
Authors: Stabile Marcelo C. C. , Garcia Andrea S. , Salomão Caroline S. C. , Bush Glenn , Guimarães André L. , Moutinho Paulo
Published: February 2022

The Amazon Forest is an unquestionable cradle of planetary biological diversity and plays a fundamental role in regional and global climate change regulation. Annual deforestation rates in the Brazilian Amazon have gone up since 2012, presenting a grim scenario for 2021. The majority of this deforestation is illegal, but a significant proportion, 11.3 million hectares of forest in privately owned land, can be legally deforested and impact local climate, compromising Brazil’s Nationally Determined Contribution (NDC) to the Paris Agreement. Thus, a fundamental question remains: how can we avoid potentially legal deforestation? Farmers and ranchers who have the right to deforest have long demanded financial incentives to keep their forests standing, but few (if any) mechanisms exist to achieve it. We developed a compensation mechanism called CONSERV, hypothesizing that legal deforestation can be avoided through targeted compensation. CONSERV can potentially contribute to climate change mitigation and foster business models geared towards conservation and increased agricultural productivity when implemented at scale. We present CONSERV’s concept and potential to become an operational mechanism for Payment for Ecosystem Services/REDD + in line with Brazil’s Native Vegetation Protection Law and NDC commitment. Furthermore, we introduce some ideas on how CONSERV ensures permanence and minimizes leakage while gaining scale. To successfully maintain climatic stability and ecosystems, we need to reduce deforestation, both illegal and legal. CONSERV can help us solve the latter.