bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-Determination Theory for Motivation in Distance Music Education
Authors: Shaheen Musbah
Published: December 2021

Many researchers have discussed the feasibility of teaching and learning practical skills, such as playing a musical instrument, through distance education. One of the central issues considered in music education is that of motivation, leading educators to wonder how students might remain motivated when learning music at a distance. In this article, I use self-determination theory (SDT) as a lens for examining existing literature on distance music education to identify elements of learning environments that may contribute to, or detract from, the fulfillment of students’ psychological needs. I oriented my reading of the literature toward offering insights on the nature of motivation in online music education and providing educators with tools informed by SDT to maintain and nurture motivation when teaching music online.
Socioeconomic Gradients in Prostate Cancer Incidence Among Canadian Males: A Trend Analysis From 1992 to 2010
Authors: Hajizadeh Mohammad , Whelan Ashley , Johnston Grace M. , Urquhart Robin
Published: December 2021

Introduction

Understanding the effects of socioeconomic status on cancer incidence and their trends over time will help inform public health interventions for cancer control. This study sought to investigate trends in socioeconomic inequalities in prostate cancer incidence among Canadian males.

Methods

Using a census division level dataset (n = 280) constructed from the Canadian Cancer Registry, Canadian Census of Population (1992, 1996, 2001, 2006) and 2011 National Household Survey, we examined the effect of socioeconomic status on prostate cancer incidence among Canadian males between 1992 and 2010. The age-adjusted concentration index was used to quantify education/income-related inequalities in prostate cancer incidence.

Results

The crude prostate cancer incidence increased from 115 to 137 per 100 000 males in Canada from 1992 to 2010 with a peak in 2007. The rate increased significantly in all but three of four western provinces. The age-adjusted concentration index showed a higher concentration of prostate cancer diagnoses among males living in high-income neighbourhoods in Canada in particular from 1996 to 2005. In contrast, the index was higher among males living in less-educated neighbourhoods in the most recent study years (2006–2010).

Conclusions

The concentration of new prostate cancer cases among high-income populations in Canada may be explained by the rise of opportunistic screening of asymptomatic males; however, this should be studied in further detail. Since we found a higher incidence rate of prostate cancer among less-educated males in Canada in recent years, risk-benefit investigation of primary prevention and opportunistic screening for less-educated males is advised.
The Enduring Importance of Parenting: Caregiving Quality and Fear-Potentiated Startle in Emerging Adults With a Child Maltreatment History
Authors: Sullivan Alexandra D. W. , Brier Zoe M. F. , Legrand Alison C. , van Stolk-Cooke Katherine , Jovanovic Tanja , Norrholm Seth D. , Garavan Hugh , Forehand Rex , Price Matthew
Published: December 2021

Background: The transition to adulthood is a period of increased risk for emergent psychopathology; emerging adults with a childhood maltreatment history are at risk for poor outcomes. Method: Using a multi-measure, transdisciplinary, cross-sectional design, this study tested whether participant-reported positive parenting, a potential resilience-promoting factor, moderated the association between clinician-rated PTSD symptom severity and a transdiagnostic maladjustment biomarker, fear-potentiated startle (FPS), in a sample of 66 emerging adults ( Myears= 18.83, SD = 0.89) with a maltreatment history. We hypothesized that characteristics of effective parenting would moderate the relation between PTSD symptoms and FPS. Results: Results indicated that elevated PTSD, as measured by the CAPS, was associated with a more severe startle reaction. The magnitude of the increase in startle reactivity was moderated by parenting such that those with more positive parenting (Accepting [relative to rejecting]: b = −0.42, p < .001; Psychologically-controlling [relative to autonomy-promoting]: b = 2.96, p = .004) had significantly less reactivity across the task at higher levels of PTSD symptoms. Conclusions: Emerging adults with childhood maltreatment histories, high levels of PTSD symptoms, and who perceive present-day high-quality caregiver support may cope better with novel stressors relative to youth lacking that support, potentially translating to better psychological outcomes.
Risk factors for corneal epithelial wound healing: Can sex play a role?
Authors: Coco Giulia , Hamill Kevin J. , Troughton Lee D. , Kaye Stephen B. , Romano Vito
Published: December 2021

Purpose

To determine if sex is associated with corneal epithelial wound healing time in patients with persistent corneal epithelial defects (PCEDs).

Methods

Retrospective case series on patients with PCED from November 2014 to January 2019. Records of 127 patients with diagnosis of PCED were reviewed. Patients with an epithelial defect that lasted more than two weeks in the absence of an active corneal infection were included. Main outcome was corneal epithelial wound healing time.

Results

55 patients (29 males) with a mean age of 65.3 ± 16.5 years were included. No difference was found between female and male patients in terms of risk factors, age, treatment strategies or intervals between visits (median of 15 days in females and 12 days in males; p = 0.24). Median duration of the PCED was 51 days (IQR 32-130), with a median number of 5 clinical visits (IQR 4-8). Female patients had significantly longer healing times (p = 0.004) and a corresponding increase in the number of clinical visits (median of 7 visits vs. 5 clinical visits in males, p = 0.012).

Conclusion

Results from this study suggest female patients with PCED might have a longer corneal epithelial wound healing duration and may therefore require earlier intervention.
Does total hip arthroplasty with high hip centre in dysplasia compromise acetabular bone stock?
Authors: Kannan Arun , Madurawe Chameka , Pierrepont Jim , McMahon Stephen
Published: December 2021

Background:

The placement of uncemented acetabular components during total hip arthroplasty (THA) in Crowe II and Crowe III dysplasia can be at the anatomic or high hip centre position.

Purposes:

Using computerised tomography data, we simulated acetabular cup placement at the anatomic hip centre and the high hip centre positions to assess whether there is a difference between the 2 in terms of bone loss from acetabular reaming and in acetabular coverage by host bone.

Methods:

The study population included a consecutive cohort of 19 patients (22 hips) with Crowe II or III dysplasia. 3-dimensional models of the pelvis were created for each patient and digital templating was used to determine the anatomic and high hip centre positions. The coordinates of the digitally templated cup positions were fed into an image processing software to estimate the amount of bone reamed, the cup coverage by host bone and the elevation from tear drop.

Results:

The mean volume of bone reamed was greater in the high hip centre position as compared to the anatomic position (27.3 ± 11. 4 cm3 vs. 19.4 ± 12.2 cm3, p  < 0.0001). The coverage of the acetabular cup by host bone was greater in the high hip centre position (87.3 ± 5.9% vs. 68.3 ± 10%). The mean elevation in the high hip centre group was 13 mm with 3 hips having a breach of the medial wall.

Conclusions:

In Crowe II and III dysplasia, placement of acetabular cups at the anatomic hip centre better preserves bone stock as compared to high hip centre placement and should be preferred in young patients requiring THA.
Re-Validation of the COmprehensive Score for Financial Toxicity (COST): Assessing the Scale’s Utility in Chronic Disease Populations
Authors: Pavela G , Fifolt M , Tison SE , Allison M , Burton BS , Ford EW
Published: December 2021

Objective:

To report the psychometric properties of the COmprehensive Score for financial Toxicity (COST) patient-reported outcome measure (PROM), an 11-item scale previously validated among patients diagnosed with cancer and receiving chemotherapy.

Methods:

Data come from a cross-sectional survey (n = 2755 response rate of 87%) of participants in a remote digital health coaching intervention collected between January 2017 and February 2019.

Results:

COST demonstrated very good internal consistency ( Cronbach’s alpha = .89) and good convergent validity. Lower financial toxicity was associated with improved physical and mental well-being HRQOL measures after controlling for covariates ( b = 0.13, P < .0001; b = 0.28, P < .0001, respectively). Supplemental analyses indicated that the COST instrument loaded on 2 factors.

Conclusions:

The COST measure of financial toxicity has good internal consistency and predictive validity in a sample of patients with chronic conditions. However, contrary to previous research examining the psychometric properties of COST in a sample of individuals with cancer, which found COST to be unidimensional, our analyses indicated that the COST measure of financial toxicity is multidimensional in a sample of individuals with chronic conditions. In particular, the items that asked about “general financial wellbeing” loaded on the second factor while “illness-related financial wellbeing” loaded on the first.
Embedded trials within national clinical audit programmes: A qualitative interview study of enablers and barriers
Authors: Alderson Sarah , Willis Thomas A , Wood Su , Lorencatto Fabiana , Francis Jill , Ivers Noah , Grimshaw Jeremy , Foy Robbie
Published: December 2021

Background

Audit and feedback entails systematic documentation of clinical performance based on explicit criteria or standards which is then fed back to professionals in a structured manner. There are potential significant returns on investment from partnerships between existing clinical audit programmes in coordinated programmes of research to test ways of improving the effect of their feedback to drive greater improvements in health care delivery and population outcomes. We explored barriers to and enablers of embedding audit and feedback trials within clinical audit programmes.

Methods

We purposively recruited participants with varied experience in embedded trials in audit programmes. We conducted qualitative semi-structured interviews, guided by behavioural theory, with researchers, clinical audit programme staff and health care professionals. Recorded interviews were transcribed, and data coded and thematically analysed.

Results

We interviewed 31 participants (9 feedback researchers, 14 audit staff and 8 healthcare professionals, many having dual roles). We identified barriers and enablers for all 14 theoretical domains but no relationship between domains and participant role. We identified four optimal conditions for sustainable collaboration from the perspectives of stakeholders: resources, that is, recognition that audit programmes need to create capacity to participate in research, and research must be adapted to fit within each programme’s constraints; logistics, namely, that partnerships need to address data sharing and audit quality, while securing research funding to ensure operational success; leadership, that is, enthusiastic and engaged audit programme leaders must motivate their team and engage local stakeholders; and relationships, meaning that trust between researchers and audit programmes must be established over time by identifying shared priorities and meeting each partner’s needs.

Conclusion

Successfully embedding research within clinical audit programmes is likely to require compromise, logistical expertise, leadership and trusting relationships to overcome perceived risks and fully realise benefits.
How beliefs about weight malleability and risk perceptions for obesity influence parents’ information seeking and feeding
Authors: Hagerman Charlotte J , Ferrer Rebecca A , Persky Susan
Published: December 2021

This study surveyed 185 parents to determine whether their perceived risk of their child developing obesity and their implicit theories about the malleability of weight independently and/or interactively predict their child-feeding and pursuit of child-related obesity risk information. Higher risk perceptions were associated with healthier feeding intentions and more information seeking. More incremental (malleable) beliefs predicted healthier feeding intentions and greater pursuit of environmental, but not genetic, information. Contrary to hypotheses, the influence of implicit theories and risk perceptions were primarily independent; however, more incremental beliefs predicted less “junk food” feeding among only parents with lower perceived risk.
Does media slant polarize compliance with science-based public health recommendations? Effects of media consumption patterns on COVID-19 attitudes and behaviors in the United States
Authors: Choi Yongjin , Fox Ashley M
Published: December 2021

Has political polarization undermined the media’ informational role during the COVID-19 pandemic? Recent studies show that politicized reporting from conservative media discouraged compliance with COVID-19 guidelines in the U.S. However, greater attention to the 24-hour news cycle may make high-consumption viewers better factually informed regardless of the source. We examine how the extent of media consumption affects people’s emotions, attitudes, and behaviors toward the pandemic. With an online survey of 1128 respondents, we found a strong convergence in anxiety and health-protective behaviors in more avid media viewers regardless of media outlet while finding a divergence in attitudes toward specific mitigation strategies.
Humbug and outrage: A study of performance, gender and affective atmosphere in the mediation of a critical parliamentary moment
Authors: Parry Katy , Johnson Beth
Published: December 2021

In a Parliament called back following its unlawful prorogation in September 2019, Prime Minister Boris Johnson touched a raw nerve by stating that the ‘best way to honour Jo Cox’s memory is to get Brexit done’. Johnson had earlier dismissed concerns about threats to Members of Parliament which echoed his inflammatory language as ‘humbug’. We examine this critical parliamentary moment in the context of broader discussions about emotionality, toxic discourse and polarisation in the United Kingdom. The study combines performance analysis of the Hansard transcripts and UK Parliament YouTube coverage of the debate, with discourse analysis of national and local newspaper coverage from 25 September to 1 October 2019. We contend that in-depth examination of this moment, alongside the subsequent journalistic commentary, contributes an original case study which works to illuminate the intersections of political performance, affective atmospheres and gender in contemporary mediated political culture.
Tackling the emotional toll together: How journalists address harassment with connective practices
Authors: Kantola Anu , Harju Anu A
Published: December 2021

In this article, we examine how journalists address and tackle online harassment by connective practices that involve joint action with peers and editors that we find are particularly effective in addressing the emotional effects of harassment. Theoretically, we bridge community of practice research with theories of emotional labour to develop a novel perspective to examine online harassment. Drawing on 22 interviews with Finnish journalists, we find three categories of connective practices that are particularly effective in tackling harassment: (1) supportive connection between the journalist and the editor; (2) shared collegial practices among peers in the newsrooms and (3) emotional engagement among peers outside the newsroom. All three categories illustrate how journalists as a community of practice develop new practices through dynamic processes innovation, improvisation, trial and error, reciprocal learning and mutual engagement. Importantly, emotional labour forms an important dimension of these practices as the journalists jointly address and tackle the emotional effects of harassment. We posit that the effectiveness of these connective practices largely stems from their ability to provide emotional support. While addressing feelings of fear, anger and shame, these shared practices also help consolidate the newly acquired knowledge and the professional identity under attack. Finally, we offer recommendations for newsrooms and journalists on how to collectively counter harassment and develop policies to address it.
Market legitimation in countercultural market change
Authors: Choi Hwanho , Burnes Bernard
Published: December 2021

Drawing on concepts of institutional work, legitimacy, and institutional logics, we investigate why countercultural markets experience institutional change and the actions institutional work market actors perform to inform institutional logics and ensure the legitimacy of countercultural markets. Although previous research suggests market changes and disruption, little attention has been paid to markets that originate from different institutional backgrounds, changes in the market experience in relation to its legitimization, and institutional work to attain legitimacy. The case of indie music in South Korea illustrates the evolution of a cultural market from the introduction of its ethos, the crisis caused by legitimacy pressures, and the transformation of the market. Using data gathered through in-depth interviews with indie labels and music consumers in South Korea, and archival sources, our research illuminates the source of market struggle and theorizes approaches that market actors perform to overcome the struggle.
Development and acceptability of a brief, evidence-based Dementia Awareness for Caregivers course in low- and middle-income countries
Authors: Stoner Charlotte R , Lakshminarayanan Monisha , Mograbi Daniel C , Vaitheswaran Sridhar , Bertrand Elodie , Schimidt Brum Paula , Durgante Helen , Ferri Cleusa P , Mkenda Sarah , Walker Richard , Dotchin Catherine , Paddick Stella-Maria , Chandra Mina , Krishna Murali , Du Bharath , Shaji Kunnukattil S , Fisher Emily , Spector Aimee
Published: December 2021

Background

Knowledge of and attitudes towards dementia vary across countries, and for caregivers in low- and middle-income countries (LMICs), access to information can be challenging. There is an urgent need for brief, easily accessible and culturally appropriate educational courses for caregivers of persons with dementia, providing much needed information whilst addressing important psychological concepts such as stigma.

Methods

An international and multidisciplinary team developed Dementia Awareness for Caregivers (DAC) courses in four stages: (1) scoping review and module agreement, (2) development of an International template (DAC-International) containing a standardised process for adding information, (3) development of local DACs using a standardised format and (4) acceptability of courses in Brazil, India and Tanzania.

Findings

The DAC-International was developed, comprising three modules: ‘What is dementia?’; ‘Positive engagement’ and ‘Caring for someone with dementia’. Three local versions were developed from this (DAC-Brazil, DAC-India and DAC-Tanzania), where additions of country-specific information included prevalent stereotypes and the addition of culturally relevant case studies. An initial field test was conducted in each country ( n = 85), which indicated acceptability to participants.

Conclusions

The methods used here resulted in culturally valid and acceptable educational courses for carers of people with dementia. Future work will consist of large-scale, formal evaluations and the development of additional local courses.
Association Study Between White Matter Microstructure and Intelligence Decline in Schizophrenia
Authors: Matsumoto Junya , Miura Kenichiro , Fukunaga Masaki , Nemoto Kiyotaka , Koshiyama Daisuke , Okada Naohiro , Morita Kentaro , Yamamori Hidenaga , Yasuda Yuka , Fujimoto Michiko , Ito Satsuki , Hasegawa Naomi , Watanabe Yoshiyuki , Kasai Kiyoto , Hashimoto Ryota
Published: December 2021

Patients with schizophrenia can exhibit intelligence decline, which is an important element of cognitive impairment. Previous magnetic resonance imaging (MRI) studies have demonstrated that patients with schizophrenia have altered gray matter structures and functional connectivity associated with intelligence decline defined by a difference between premorbid and current intelligence quotients (IQs). However, it has remained unclear whether white matter microstructures are related to intelligence decline. In the present study, the indices of diffusion tensor imaging (DTI) obtained from 138 patients with schizophrenia and 554 healthy controls were analyzed. The patients were classified into three subgroups based on intelligence decline: deteriorated (94 patients), preserved (42 patients), and compromised IQ (2 patients) groups. Given that the DTI of each subject was acquired using either one of two different MRI scanners, we analyzed DTI indices separately for each scanner group. In the comparison between the deteriorated IQ group and the healthy controls, differences in some DTI indices were noted in three regions of interest irrespective of the MRI scanners, whereas differences in only one region of interest were noted between the preserved IQ group and the healthy controls. However, the comparisons between the deteriorated and preserved IQ groups did not show any reproducible differences. Together with the previous findings, it is thought that gray matter structures and functional connectivity are more promising as markers of intelligence decline in schizophrenia than white matter microstructures.
Energy efficient multi-hop routing protocol for smart vehicle monitoring using intelligent sensor networks
Authors: Teekaraman Yuvaraja , Manoharan Hariprasath , Kuppusamy Ramya , Urooj Shabana , Alrowais Fadwa
Published: December 2021

This article focuses on intensifying in-vehicle biological wireless sensor networks for the persistence of monitoring the information on a precise vehicle. The wireless sensor networks will have enormous amount of nodules which are interrelated with each other. Therefore, these wireless sensor networks can be installed on a vehicle not only for monitoring perseverance but also for corroborating security with the support of a Global Positioning System expedient. In addition, the projected work focuses on reliable communiqué which is defined in terms of network reliability with discrepancy in reporting rate at each base station. To validate the efficiency of the proposed scheme, the simulation has been abetted using network simulator (NS2) and the outcomes indicate that when the sensors are installed, a robust system can be obtained with improved data transfer between the base stations. Moreover, a fortified in-vehicular sensor can be fixed in each vehicle with minimized path loss.
Can Ultrasound-Guided Regional Anesthesia Techniques For Tracheostomy Be An Alternative To General Anesthesia?
Authors: Şahin Ayhan , Baran Onur , Gültekin Ahmet , Şahin Gülcan Gücer , Ersözlü Tolga , Arar Cavidan
Published: December 2021

Introduction The cervical plexus block (CPB) has been used for a long time for both analgesia and anesthesia in carotid endarterectomy and thyroid operations. To be unfamiliar with the technique and its perceived difficulty, potential risks, and possible adverse effects such as intravascular injection has limited broader use before the practical use of ultrasound. We hypothesize that the cervical plexus block can provide adequate anesthesia in tracheostomy cases and provide excellent anesthesia comfort when combined with a translaryngeal block. Methods This double-blinded, randomized 29 patients undergoing primary tracheostomy operation to receive either CPB (Group S) or CPB with translaryngeal block (Group ST). The primary outcome was cumulated analgesic consumption during the first 24 postoperative hours. Secondary outcomes were as follows: pain related to incision, patient tolerance as assessed by tracheostomy cannula comfort score, cough and gag, pain at rest, nausea and vomiting, and time to first analgesic demand. Results The patient tolerance for tracheostomy was higher in Group ST than Group S. The median tracheostomy cannula comfort score was 4.0 in Group S. In contrast, the median score was significantly lower in group ST (P<.001). The cough and gag reflex scores were significantly lower in Group ST than Group S (1.0 vs 4.0, P<.001). Conclusion This trial supported the hypothesis that the CPB combined with the translaryngeal block yields excellent anesthesia for tracheostomies. The technique we briefly described, in a way, is the equivalent of awake fiberoptic intubation to awake tracheostomy with minimal sedation adjusted according to airway patency.
Explicit feature disentanglement for visual place recognition across appearance changes
Authors: Tang Li , Wang Yue , Tan Qimeng , Xiong Rong
Published: December 2021

In the long-term deployment of mobile robots, changing appearance brings challenges for localization. When a robot travels to the same place or restarts from an existing map, global localization is needed, where place recognition provides coarse position information. For visual sensors, changing appearances such as the transition from day to night and seasonal variation can reduce the performance of a visual place recognition system. To address this problem, we propose to learn domain-unrelated features across extreme changing appearance, where a domain denotes a specific appearance condition, such as a season or a kind of weather. We use an adversarial network with two discriminators to disentangle domain-related features and domain-unrelated features from images, and the domain-unrelated features are used as descriptors in place recognition. Provided images from different domains, our network is trained in a self-supervised manner which does not require correspondences between these domains. Besides, our feature extractors are shared among all domains, making it possible to contain more appearance without increasing model complexity. Qualitative and quantitative results on two toy cases are presented to show that our network can disentangle domain-related and domain-unrelated features from given data. Experiments on three public datasets and one proposed dataset for visual place recognition are conducted to illustrate the performance of our method compared with several typical algorithms. Besides, an ablation study is designed to validate the effectiveness of the introduced discriminators in our network. Additionally, we use a four-domain dataset to verify that the network can extend to multiple domains with one model while achieving similar performance.
Iconic war images and the myth of the ‘good American Soldier’
Authors: MacKenzie Megan
Published: December 2021

This article explores the ‘good American soldier’ as a gendered ideal type shaped by, and reproductive of, myths about American military success, romantic notions of small-town working and white America, notions of heterosexual virility, and ableist stereotypes about personal resilience. Drawing from an analysis of 10 years of media coverage of an iconic image dubbed the ‘Marlboro Marine’, the article outlines three specific myths linked to the ‘good American soldier’, in order to provide an insight into ideals of militarized masculinity and the gendered myths that shape American nationalism and identity. In developing this analysis, the article extends existing work on military masculinities by introducing the ‘good American soldier’ ideal type and explores the multiple myths associated with this ideal type. The article also demonstrates how a media narrative analysis that covers an extended period of time makes it possible to observe shifting narratives associated with the ‘good American soldier’.
Tumour necrosis factor inhibitors in inflammatory bowel disease: the story continues
Authors: Peyrin-Biroulet Laurent , Sandborn William J. , Panaccione Remo , Domènech Eugeni , Pouillon Lieven , Siegmund Britta , Danese Silvio , Ghosh Subrata
Published: December 2021

In the 1990s, tumour necrosis factor-α inhibitor therapy ushered in the biologic therapy era for inflammatory bowel disease, leading to marked improvements in treatment options and patient outcomes. There are currently four tumour necrosis factor-α inhibitors approved as treatments for ulcerative colitis and/or Crohn’s disease: infliximab, adalimumab, golimumab and certolizumab pegol. Despite the clear benefits of tumour necrosis factor-α inhibitors, a subset of patients with inflammatory bowel disease either do not respond, experience a loss of response after initial clinical improvement or report intolerance to anti-tumour necrosis factor-α therapy. Optimizing outcomes of these agents may be achieved through earlier intervention, the use of therapeutic drug monitoring and thoughtful switching within class. To complement these approaches, evolving predictive biomarkers may help inform and optimize clinical decision making by identifying patients who might potentially benefit from an alternative treatment strategy. This review will focus on the current use of tumour necrosis factor-α inhibitors in inflammatory bowel disease and the application of personalized medicine to improve future outcomes for all patients.
Naringenin as a Possible Candidate Against SARS-CoV-2 Infection and in the Pathogenesis of COVID-19
Authors: Agrawal Pawan K. , Agrawal Chandan , Blunden Gerald
Published: December 2021

Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other health beneficial activities, such as immune-stimulating and anti-inflammatory actions that could play a role in contributing, to some extent, to either preventing or alleviating coronavirus infection. Several computational studies have identified naringenin as one of the prominent flavonoids that can possibly inhibit internalization of the virus, virus-host interactions that trigger the cytokine storm, and replication of the virus. This review highlights the antiviral potential of naringenin in COVID-19 associated risk factors and its predicted therapeutic targets against SARS-CoV-2 infection.
Traveler Attitudes Toward Biometric Data-Enabled Hotel Services: Can Risk Education Play a Role?
Authors: Lehto Xinran Y. , Park Soona , Mohamed Mohamed E. , Lehto Mark R.
Published: December 2021

This study compares attitudes toward the use of biometrics data-enabled services in hotels of prospective travelers before and after receiving information about the risks and benefits of disclosing biometric data and about how the disclosed data are being utilized. This was done based on a sample of 579 U.S. respondents, using a split-plot scenario-based experimental design. The results revealed that the respondents did not show enthusiastic support for biometrics-based hotel services. Most sampled respondents did not view such services as highly desirable or as having a positive influence on their sense of well-being. Significant demographic differences were observed between prospective travelers. Females and older respondents in particular provided significantly lower ratings of biometric-enabled services on both desirability and effects on well-being. Significant changes in respondents’ ratings were also observed when information was given about the risks and benefits of disclosing biometric data and how the disclosed data were being utilized. That is, respondents’ ratings were lower when information was given about the risks and for scenarios where the data were utilized in ways that increased risk. Overall, these results are consistent with rational choice theory and demonstrate a strong risk-education effect or information-nudge effect on consumer acceptance of commercial use in hotels of artificial intelligence technology. The study outcomes also provide insight for developing potential guardrails and parameters for designing intelligent hospitality services.
The Huddle: A Daily Dose of Communication
Authors: Schatz Mary , Bergren Martha Dewey
Published: December 2021

Teamwork and communication are critical to ensure safe and quality care for students. A huddle offers the team a daily dedicated time to connect with each other. Huddles are short, regular debriefings designed to engage clinical staff in discussions about existing or emerging safety issues. The huddle was already systematically and uniformly part of the daily practice at Akron Children’s Hospital’s School Health Services daily schedule prior to COVID-19. The pandemic increased the need for the daily huddle. The fluid and frequently changing guidelines, personal protective equipment, and mitigation considerations has increased nursing anxiety and has made regular communication and daily debriefing even more important. Akron Children’s Hospital School Health Services has used huddle for over 10 years with excellent quality, team building, and nurse satisfaction outcomes.
Physiological Reloading Recovers Histologically Disuse Atrophy of the Articular Cartilage and Bone by Hindlimb Suspension in Rat Knee Joint
Authors: Takahashi Ikufumi , Matsuzaki Taro , Kuroki Hiroshi , Hoso Masahiro
Published: December 2021

Objective

This study aimed to clarify physiological reloading on disuse atrophy of the articular cartilage and bone in the rat knee using the hindlimb suspension model.

Design

Thirty male rats were divided into 3 experimental groups: control group, hindlimb suspension group, and reloading after hindlimb suspension group. Histological changes in the articular cartilage and bone of the tibia were evaluated by histomorphometrical and immunohistochemical analyses at 2 and 4 weeks after reloading.

Results

The thinning and loss of matrix staining in the articular cartilage and the decrease in bone volume induced by hindlimb suspension recovered to the same level as the control group after 2 weeks of reloading. The proportion of the noncalcified and calcified layers of the articular cartilage and the thinning of subchondral bone recovered to the same level as the control group after 4 weeks of reloading.

Conclusions

Disuse atrophy of the articular cartilage and bone induced by hindlimb suspension in the tibia of rats was improved by physiological reloading.
The challenge to differentiate between sarcoma or adrenal carcinoma—an observational study
Authors: Dobrindt Eva M , Saeger Wolfgang , Bläker Hendrik , Mogl Martina T , Bahra Marcus , Pratschke Johann , Rayes Nada
Published: December 2021

Background

Adrenal sarcomas are rare malignant tumors with structural and clinical similarities to sarcomatoid adrenocortical carcinoma. Preoperative diagnosis of tumors of the adrenal gland can be challenging and often misleading thus detaining patients from appropriate oncological strategies.

Objective

This analysis of a case series evaluated the predictive capability of the primary clinical diagnosis in case of malignancies of the adrenal gland.

Methods

Thirty two patients were treated from 2009 to 2015 at our clinic and analyzed retrospectively. All patients had computed tomography and/or magnet resonance imaging and a primary histopathological examination at our institution after surgery. Ten questionable cases were surveyed by a reference pathologist.

Results

Twelve out of 32 diagnoses had to be revised (37.5%). Only 15 out of 24 tumors primarily classified as adrenocortical carcinoma were finally described as primary adrenal cancer. We found two leiomyosarcomas, one liposarcoma, one sarcomatoid adrenocortical carcinoma, and one epitheloid angiosarcoma among 12 misleading diagnoses. Other tumors turned out to be metastases of lung, hepatocellular, and neuroendocrine tumors. Larger tumors were significantly more often correctly diagnosed compared to smaller tumors. Four patients of the group of revised diagnoses died whereas all patients with confirmed diagnoses survived during the follow-up.

Conclusion

Preoperative assessment of tumors of the adrenal gland is still challenging. In case of wrong primary diagnosis, the prognosis could be impaired due to inadequate surgical procedures or insufficient preoperative oncological treatment.
Democracy, external threat, and military spending
Authors: Hauenstein Matthew , Smith Matthew , Souva Mark
Published: December 2021

A number of studies find that democracies spend less on their military than non-democracies. Yet there are well known counter-examples, including but not limited to the United States and Israel. We contend that these counter-examples are part of a larger pattern. The relationship between regime type and military spending is conditional on external threat. Among countries that do not perceive a significant external threat to their interests, democracies allocate considerably less to the military than non-democracies. However, democracies with a significant external threat do not allocate less to the military than non-democracies. The reason prior research consistently finds that democracies, on average, spend less on the military, even while controlling for external threat, is that democracies are much less likely to have a high external threat. For example, autocracies are nearly twice as likely as democracies to have a significant external threat in our sample. An empirical analysis of military spending from 1952–2000 is consistent with these expectations.
Do people want smarter ballots?
Authors: Blais André , Plescia Carolina , Sevi Semra
Published: December 2021

We ascertain whether citizens want to have smart ballots, that is, whether they appreciate having the possibility to express some support for more than one option (expression across options) and to indicate different levels of support for these options (expression within options). We conducted two independent yet complementary survey experiments at the time of the Super Tuesday Democratic primaries to examine which voting method citizens prefer, one with the real candidates in the states holding Democratic primaries and one with fictitious candidates in the whole country. In both surveys, respondents were asked to vote using four different voting rules: single, approval, rank, and point (score). After they cast their vote, respondents were asked how satisfied they were using each voting method. The findings are consistent in both studies: the single vote is the most preferred voting method. We show that this is a reflection of a status quo bias, as citizens’ views are strongly correlated with age.
Arterial hypertension in women: Menopause as a risk window
Authors: Okeahialam Basil N , Agbo Hadiza , Chuhwak Evelyn , Isiguzoro Ikechukwu
Published: December 2021

Objectives

Cardiovascular diseases (CVD) exert a heavy toll on health of women, mainly due to hypertension said to cluster around the period of transition to menopause. This makes this period a good window to target for prevention and control. We therefore sought to determine if this period really heralds arterial hypertension and CVD in women in our environment.

Study design

We secondarily analysed our population data on CVD risk factors in free living rural residents.

Main outcome variables

The data considered were blood pressure, anthropometric and biochemical variables in women stratified based on menstruation status.

Results

There were 488 females, with 218 still menstruating. They were younger ( p = .000), had lower systolic and diastolic blood pressures ( p = .000), lower anthropometric indices attaining significance only with waist circumference ( p = .001) and lower total cholesterol ( p = .001). Controlling for age, statistically significant differences remained for systolic and diastolic blood pressures, body mass index, waist and hip circumferences, and total cholesterol.

Conclusion

The menopause transition comes with a worse CVD profile. Blood pressure rises and so are the anthropometric variables and some biochemical parameters that fuel CVD. This could be ascribed to age which is higher with those post-menopausal. Controlling for age in this cohort still showed that transiting from pre- to post-menopause still came with CVD burden. Clinicians should take the opportunity presented by menopause transition to screen for CVD risk factors and initiate either preventive or control measures to mitigate morbi-mortality consequences.
Feasibility of cognitive rehabilitation in patients with advanced multiple sclerosis: A pilot study
Authors: Prouskas Stefanos E , Chiaravalloti Nancy D , Kant Neeltje , Ball Karlene K , de Groot Vincent , Uitdehaag Bernard MJ , Geurts Jeroen JG , Kooij Elizabeth A , Hulst Hanneke E
Published: December 2021

Background

The feasibility of cognitive rehabilitation is rarely investigated in patients with advanced multiple sclerosis.

Methods

Eighteen patients with advanced multiple sclerosis (median EDSS = 7.5) were randomized into restorative or compensatory cognitive rehabilitation. Feasibility was determined by adherence rate, completion rate, patient satisfaction, self-reported fatigue, training difficulty, and training duration.

Results

Adherence rates and completion rates were over 70%, and patients were highly satisfied in both groups. Energy levels decreased minimally during the sessions (pre = 6.9 vs post = 6.4). Training difficulty (4.6) and duration (5.7) were close to ideal (scale 1–10, 5 = ideal).

Conclusions

Cognitive rehabilitation, with minor adjustments, appears feasible in patients with advanced multiple sclerosis.
Nosocomial Outbreak of SARS-CoV-2 in a Non-COVID Zone of a Tertiary Care Hospital of North India: Need to Upgrade Infection Control Practices
Authors: Rana Kirtan , Sharma Bhawna , Lakshmi Pinnaka Venkata Maha , Kaur ManharPreet , Singh Mini P. , Singh Ranjana , Aggarwal Sameer , Biswal Manisha
Published: December 2021

Background

Hospital acquired infections are preventable cause for morbidity and mortality worldwide. In the current pandemic era proper implementation of infection control measures can prevent the spread of such infections including SARS-CoV 2. The study was done to identified the source and reason for spread of COVID-19 infection and devise recommendations to halt the progress of infection in a non-COVID area.

Methods

An outbreak in a non-COVID area of a tertiary care hospital was investigated by the infection control team along with the epidemiologist when they were notified about the rising cases of COVID-19 from Advanced Trauma Center’s (ATC) disaster ward. The time, place and person distribution of the cases were studied. Recommendations based on gaps identified were developed onsite and implemented to control the outbreak.

Results

The outbreak lasted from 19th December 2020 to 12th January 2021, affecting 34 people (25 patients and 9 health care workers). The attack rate was 9.2%. We identified the causes of current outbreak as compromises in infection prevention measures, high bed patient ratio, irregularities in the ventilation system, overcrowding by patient attendants and communication gaps between nursing officers and doctors. Measures required to control the outbreak were implemented and no cases were reported for 2 weeks following the last positive case.

Conclusion

Non-COVID areas of hospitals are also at risk of nosocomial outbreaks of SARS-CoV 2 and therefore strict infection prevention measures those designated to COVID areas should be followed in non-COVID zones also to prevent such outbreaks.
Propaganda and Radicalization: The Case of Daesh in Iran
Authors: Kadivar Jamileh
Published: December 2021

The process of becoming radicalized and joining extremist groups like Daesh, in countries with a Shi’a majority, such as Iran, is a controversial topic that has not received sufficient attention in the literature. This study examines Daesh’s media content in Farsi and seeks to provide an analysis of Daesh’s main messages, which have the primary objective of profoundly impacting their target audiences in Iran. This study collected data from 16 Iranian members of Daesh to discover how they were radicalized and why they decided to join Daesh. This study seeks to understand whether the media and Daesh’s propaganda are indeed the key reasons behind the radicalization of Daesh’s Iranian members and the creation of others’ perception of their mindsets against Iran and its Shi’a population, and to discover other possible factors that play a role in the radicalization process. While Daesh media and messages hold salience in relation to the Daeshization of some, studying such complex socio-political issues is rooted in an amalgamation of different personal, social, political, economic, and cultural push and pull factors. Such phenomena cannot, therefore, be reduced to only one of the mentioned elements.
Using Principal–Steward Contracting and Scenario Planning to Manage Megaprojects
Authors: Rodney Turner J.
Published: December 2021

Performance on megaprojects is dismal. Megaprojects are complex, but people use constructs inappropriate in complex situations for their management, particularly contractual arrangements based on principal–agent governance and conventional project management, which is good at solving puzzles, but not at enlightening mysteries. I review current thinking. Principal–steward contracting is a liberal governance structure required in complex situations. Conventional project management emphasizes control at the expense of innovation. In cases of high uncertainty, innovation is required as unexpected events occur. Scenario planning is offered as a way of approaching the management of complex megaprojects, to construct narratives, and to identify alternative outcomes.
Upfront therapy: the case for continuous treatment
Authors: Tam Constantine S.
Published: December 2021

Both BTKi and BCL2i are regarded as standards of care for frontline treatment of CLL. In this paper, I present the arguments for favoring BTKi as initial therapy. Venetoclax-based regimens have the advantage of being fixed in duration, but patients with select high-risk features may experience inferior PFS relative to those without high-risk features.
When does a PNH clone have clinical significance?
Authors: Babushok Daria V.
Published: December 2021

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired blood disease caused by somatic mutations in the phosphatidylinositol glycan class A (PIGA) gene required to produce glycophosphatidyl inositol (GPI) anchors. Although PNH cells are readily identified by flow cytometry due to their deficiency of GPI-anchored proteins, the assessment of the clinical significance of a PNH clone is more nuanced. The interpretation of results requires an understanding of PNH pathogenesis and its relationship to immune-mediated bone marrow failure. Only about one-third of patients with PNH clones have classical PNH disease with overt hemolysis, its associated symptoms, and the highly prothrombotic state characteristic of PNH. Patients with classical PNH benefit the most from complement inhibitors. In contrast, two-thirds of PNH clones occur in patients whose clinical presentation is that of bone marrow failure with few, if any, PNH-related symptoms. The clinical presentations are closely associated with PNH clone size. Although exceptions occur, bone marrow failure patients usually have smaller, subclinical PNH clones. This review addresses the common scenarios that arise in evaluating the clinical significance of PNH clones and provides practical guidelines for approaching a patient with a positive PNH result.
Modified T cells as therapeutic agents
Authors: Singh Nathan
Published: December 2021

Immunotherapy is now a well-established modality in the treatment of cancer. Although several platforms to redirect the immune response exist, the use of genetically modified T cells has garnered particular attention in recent years. This is due, in large part, to their success in the treatment of B-cell malignancies. Adoptively transferred T cells have also demonstrated efficacy in the treatment of systemic viral infections that occur following hematopoietic cell transplantation prior to immune reconstitution. Here we discuss the techniques that enable redirection of T lymphocytes to treat cancer or infection and the current indications for these therapies.