bluuebunny/crossref_metadata_2025 huggingface dataset:
Phase 1 study of lintuzumab-Ac225 combined with CLAG-M salvage therapy in relapsed/refractory acute myeloid leukemia
Authors: Abedin Sameem , Murthy Guru Subramanian Guru , Hamadani Mehdi , Carlson Karen , Runaas Lyndsey , Gauger Katelyn , Desai Avinash , Chen Mary , Li Kate , Rotibi Mojisola , Syed Umar , Harrington Alexandra , Atallah Ehab , Michaelis Laura
Published: December 2024

Lintuzumab-Ac255 is an humanized anti-CD33 antibody linked to Actinium-225 that delivers high-energy alpha-particles to tumor cells, leading to double-strand DNA breaks and cell death. This phase 1 study assessed the safety and efficacy of lintuzumab-Ac225 after CLAG-M salvage therapy in patients with relapsed/refractory acute myeloid leukemia (R/R AML). Primary objectives were to determine the maximum tolerated dose (MTD), recommended phase 2 dose (RP2D) and safety profile. Using a 3+3 dose-escalation design, 21 patients were enrolled sequentially into 4 cohorts to receive a lintuzumab-Ac225 infusion (0.25-1.0 µCi/kg) 7 (+2) days after CLAG-M (days 1-6); 5 additional patients received the RP2D. Of 23 efficacy-evaluable patients, 86.7% had high-risk disease. The MTD was 1.0 µCi/kg; the RP2D was 0.75 µCi/kg. The most common grade 3/4 adverse events were febrile neutropenia (65.4%), decreased white blood cells (50%), and decreased neutrophil count (42.3%). The composite complete remission rates (CR/CR with incomplete count recovery) were 56.6% overall, 50% in patients with mutated TP53, and 38.5% in prior venetoclax-treated patients. Measurable residual disease (MRD)-negativity occurred in 75% of 12 evaluable patients. Lintuzumab-Ac225 plus CLAG-M was well tolerated with expected, manageable toxicities, while yielding deep responses characterized by high rates of MRD-negativity including in high-risk R/R AML populations.
Gestational weight gain and its determinant factors among women who had Antenatal Care visit in public health facilities of Debre Markos Town, Northwest Ethiopia, 2023
Authors: Alemu Mulu , Alemayehu Tefera , Messelu Mengistu Abebe , Alemu Tsehay , Mekonnen Habtamu , Aderaw Alehegn , Agedew Eskeziyaw , Endalifer Melese Linger
Published: December 2024

Background: Women who do not gain enough weight during pregnancy have a risk of bearing a baby with a low birth weight. However, research on gestational weight gain and its determinants is scarce in developing countries, including Ethiopia. Therefore, this study aimed to assess adequate gestational weight gain and its determinant factors among pregnant women who had ANC follow-up visits at public health facilities in Debre Markos town, Northwest Ethiopia.
Methods: An institutional-based cross-sectional study design was conducted from January 1, 2023 to June 30, 2023. A systematic random sampling technique was employed to select 532 study participants. Data was entered into Epidata Version 3.1 and exported into SPSS Version 25 for statistical analysis. A hosmer lemeshow model fitness was checked. Bivariable and multivariable binary logistic regression analyses were conducted to observe the statistical association between the outcome variable and independent variables. An adjusted odds ratio with a 95% confidence interval was used to report the strength of the association.
Results: This study found that 30.9% (95% CI: 27.0, 34.7) of women gained adequate gestational weight. Number of ANC visits (AOR = 5.9, 95% CI: 3.02, 14.7), Meal frequency (AOR = 3.2, 95% CI: 1.56, 6.67), and consumption of animal source foods at least once per week (AOR = 2.7, 95% CI: 1.47, 4.90) were statistically associated with adequate weight gain.
Conclusion and recommendation: Nearly one-third of pregnant women gain adequate gestational weight. Women who had frequent ANC visits, meal frequency, and consumption of animal source foods at least once per week were significantly associated with adequate gestational weight gain. Women centered nutritional counseling and support is essential to improve weight gain during pregnancy.
Tissue oxygenation flow differences in radiation therapy treated breast cancer subjects using near-infrared spectroscopy
Authors: Leiva Kevin , Spencer Sydni , Lamptey Manuel , Robledo Edwin A. , Beiner Corina , Rodrigues Maria Amelia , Fagundes Marcio , Panoff Joseph , Chuong Michael D. , Wu Wensong , Godavarty Anuradha
Published: December 2024

Purpose
At least 95% of breast cancer patients treated with radiation therapy (RT) may experience radiation dermatitis (RD) and or skin hyperpigmentation (SH). Assessment of severity or grading of RD is clinically visual and hence subjective. The objective of this analysis was to determine sub-clinical oxygenation flow pattern changes in response to RT in breast cancer patients using near-infrared spectroscopic imaging and correlate these changes to RD and SH grading.
Methods
A 4–8 week longitudinal pilot imaging study was carried out on 10 RT-treated breast cancer patients. Non-contact spatio-temporal near-infrared spectroscopic (NIRS) imaging was performed on the irradiated ipsilateral and the contralateral chest wall regions in response to a vaso-constricting breath-hold paradigm to observe differences in the vascular response before RT, at the end of RT, and 1–2 months after RT.
Results
Oxygen saturation increased during post-breath of the 20-sec breath hold paradigm in all subjects, demonstrating a vascular response. Oxygenation flow correlation between the irradiation and non-irradiated chest wall region differed with RT treatment. Significant changes (p < 0.1) in oxygenation flow correlations before and after RT was observed compared to baseline, with onset of SH. Similarly, significant changes (p < 0.1) in oxygenation flow correlations after RT and during follow-up was observed compared to after RT, in the presence of RD.
Conclusions
A novel oxygenation flow pattern approach has been developed to understand the physiological changes responsible for RD and SH that occur as a result of breast RT.
NDVI and vegetation volume as predictors of urban bird diversity
Authors: Fairbairn Andrew J. , Katholnigg Sophia , Leichtle Tobias , Merkens Lisa , Schroll Louis , Weisser Wolfgang W. , Meyer Sebastian T.
Published: December 2024

Urban expansion and densification pose a challenge to urban biodiversity. Rapid estimation of biodiversity could help urban planners balance development and conservation goals. While the Normalised Difference Vegetation Index (NDVI) has proven useful for predicting urban bird diversity, new products derived from remote sensing, such as vegetation volume, could provide more detailed descriptions of available habitat, potentially improving biodiversity predictions. We evaluated the effectiveness of NDVI and vegetation volume as predictors of urban bird diversity and local community composition for different buffers around 86 sampling points in Munich, Germany. Using linear models, we showed that a 100 m buffer best described bird diversity (highest r2) for both NDVI and vegetation volume compared to the other buffers. Contrary to expectations, NDVI was superior to vegetation volume in predicting bird diversity (mean r2 NDVI = 0.45, mean r2 vegetation volume 0.37). We found a shift in community composition from species associated with human-modified landscapes to those associated with forests along an urban greenness gradient. In contrast to diversity, we found that vegetation volume was slightly better at predicting community composition. Using NDVI to predict bird diversity across Munich, we demonstrated its potential for predicting city-wide bird diversity. We discuss how such predictive maps can be used for urban planning and conservation. As urbanisation continues to impact global biodiversity, refining ecological models for urban planning will be crucial to developing more biodiverse urban environments.
„[A]ls könnte es sich in Ewigkeit nicht satt lachen“.
Authors: Keller Deborah
Published: December 2024

[English title and abstract below]
Meinrad Lienert (1865–1933) ist heute vor allem noch bekannt für seine Mundartlyrik und seine patriotischen Schweizer Sagen und Heldengeschichten. Der Jugend erzählt (1914), die immer wieder neu aufgelegt wurden. Diese haben den Blick verstellt auf seine inzwischen vergriffenen Kindergeschichten (Das war eine goldene Zeit! [1906]; Das Bergspieglein [1910]), die der intentionalen Kinderliteratur zuzurechnen sind. Voller Schalk und Humor bestechen sie insbesondere durch die kunstvoll-doppelbödige Mimesis kindlicher Dialoge. Gerade dort, wo sie letzte Dinge verhandeln – so etwa im Spiel mit den Totenköpfen im Beinhaus in der Erzählung Zum blauen See –, ist ihnen eine Poetik des Komischen eingeschrieben. Diese Feier des Lachens lässt auch Kritik an der engen katholischen Lebenswelt der damaligen Innerschweiz anklingen.
Die Untersuchung – mit narratologischem Zugang und unter Beizug unterschiedlicher Komik-Theorien sowie mit einem Blick auf Editions- und Rezeptionsgeschichte – zeigt auch, dass die ambigue Adressierung, die zu Brüchen in der Tradierung geführt hat, zur literarischen Eigenheit dieser Kindergeschichten gehört und wesentlich in den Verfahren der Komik wie auch der Verwendung des Motivs des Lachens begründet ist.
 
„[A]ls könnte es sich in Ewigkeit nicht satt lachen“.Comedy and laughter in Meinrad Lienert’s Children’s Stories
Meinrad Lienert (1865–1933) is still best known today for his dialect poetry and his patriotic Schweizer Sagen und Heldengeschichten (1914), which have been frequently reprinted. These have obscured the view of his stories (Das war eine goldene Zeit! [1906]; Das Bergspieglein [1910]), now out of print, which can be categorised as having been written specifically for children. Full of mischief and humour, the stories are particularly captivating with their artful and ambiguous mimesis of children’s dialogues. Especially at the points at which they deal with the final things – for example when the children play with skulls in the charnel house in the story „Zum blauen See” – a genuine poetics of humour is evident. This celebration of laughter also echoes criticism of the narrow Catholic world of life in central Switzerland at the time. The article employs a narratological approach and draws on various humour theories in addition to looking at the history of editions and reception of these stories. It shows that the ambiguous form of address, which has led to disruptions in their tradition, is an inseparable part of their literary uniqueness and is essentially rooted in the comic procedures as well as in the use of the motif of laughter.
Violente Komik in Cartoons am Beispiel von Tom and Jerry
Authors: Höch Kristina
Published: December 2024

[English title and abstract below]
Darf über mediale Gewalt gelacht werden? Cartoons sind seit Jahrzehnten Bestandteil vieler Kindheiten und basieren in ihrer Komik nicht selten auf gewalttätigen Inhalten. Ein Zeichentrick-Duo, das seit 1940 über Leinwand und Fernseher flimmert und auch heute ohne Violenz nicht existieren kann, wird von Kater Tom und Maus Jerry gebildet. Anfänglich nur im Kino zu sehen, sind sie inzwischen durch Fernsehen und Streaming rund um die Uhr verfügbar. Durch meist nonverbale Handlungen werden die Akte der Gewalt in den Tom and Jerry-Cartoons universal als komisch verstanden. Wie kommunizieren diese Cartoons mit den Zuschauer:innen, um ein Lachen zu fördern, das fiktive Gewalt zwar komisch findet, diese aber nicht als bedrohlich empfindet und in der ‚realen Welt‘ nicht bejaht? Um dies zu klären, nimmt der Beitrag Bezug auf inszenatorische und narrative Strategien. Anthropomorphisierung, Inkongruenzen, Ästhetisierung und das Spielen mit Repräsentationsordnungen schaffen eine Cartoon-Welt, in der die Gewaltdarstellungen zwar drastisch sind, aber ohne Konsequenz für die Protagonist:innen bleiben. Die Darstellung von Gewalt wird nicht glorifiziert, das Nicht-Harmlose wird mit Harmlosem kombiniert, damit darüber gelacht werden kann. Durch das Anregen kognitiver Aktivitäten und durch die Aktivierung von Wissen und Sehgewohnheiten entfaltet sich auf visueller und auditiver Ebene aus ästhetischer Distanz ein komischer Rahmen, in den die gewalttätigen Handlungen implementiert werden.
 
Violent Comedy in Cartoons: The Example of Tom and JerryAnthropomorphisation, Incongruity and Representation
Is it permissible to laugh at media violence? Cartoons have been a part of many childhoods for decades and often base their humour on violent content. Tom and Jerry are a cat and mouse cartoon duo that have been flickering across screens and televisions since 1940 and cannot exist without violence. Initially only seen in cinemas, they are now available around the clock thanks to television and streaming. Through mostly non-verbal actions, the acts of violence in Tom and Jerry cartoons are universally taken to be comical. How do these cartoons communicate with viewers to encourage laughter that finds fictional violence funny but does not perceive it as threatening or condone it in the ‘real world’? To clarify this, the article refers to staging and narrative strategies. Anthropomorphisation, incongruities, aestheticisation and playing with orders of representation create a cartoon world in which depictions of violence are drastic but without consequence for the protagonists. Violence is not glorified; the harmful is combined with the harmless so that it can be laughed at. By stimulating cognitive activities and activating knowledge and viewing habits, a comic framework of aesthetic distance is created, on visual as well as audio levels, into which the violent acts are embedded.
“Because she can fly”
Authors: Duthoy  Leander
Published: December 2024

What makes a fictional character someone’s favourite? One of the factors scholars have explored is overlapping identity markers, for instance when boy readers favour boy characters. This article extends that discussion to age by discussing data gathered in individual interviews and focus-group conversations with 18 readers between the ages of 9 and 75. In the interviews, readers were asked about their favourite character in the children’s book Iep! (1996) by Joke van Leeuwen. Readers up to the age of 14 all selected younger characters as their favourites, whereas older readers selected favourite characters from a wider range of age groups, including younger characters. Younger readers named distinct traits as their reason for selecting a character as their favourite, such as “Because she can fly”, whereas adult readers also cited external factors for liking a character, such as a character reminding them of someone. Regarding the characters that readers did not like, readers up to the age of 11 were unable to select a character they did not like, whereas the majority of adults found this easy. Of these unpopular characters, only a small minority were children; in the main, adult readers disliked adult characters. Interestingly, several child readers defended adult characters disliked by adult readers.
Pelatihan dan Pengembangan Materi Robotik dan Pemrograman untuk Anak Berkebutuhan Khusus
Authors: Sebastian Danny , Restyandito  , Nugroho Justinus Putranto Agung
Published: December 2024

Membuat modul pembelajaran untuk anak berkebutuhan khusus memerlukan penyesuaian yang mendalam agar sesuai dengan kebutuhan individu anak, baik di bidang intelektual maupun perilaku. Pendekatan individual (Individualized Approach) menekankan adaptasi materi berdasarkan kemampuan dan minat spesifik anak. Contohnya dalam modul pemrograman, platform seperti Scratch dapat digunakan untuk memperkenalkan konsep dengan cara visual dan interaktif yang lebih mudah dipahami. Sementara itu, dalam modul LEGO, kegiatan disusun agar anak dapat merakit secara bertahap menggunakan panduan visual dan pemecahan tugas kompleks menjadi langkah kecil, mengurangi rasa frustrasi dan meningkatkan pemahaman bertahap. Struktur dan rutinitas membantu anak-anak dengan gangguan perilaku untuk tetap fokus, sementara pendekatan multisensori memungkinkan pemrosesan informasi melalui indera. Dengan metode seperti task analysis, materi yang kompleks dibagi menjadi komponen yang lebih sederhana agar anak dapat belajar dengan cara yang teratur dan jelas. Kombinasi pendekatan ini memastikan modul pembelajaran efektif dan inklusif, terutama ketika alat seperti LEGO digunakan sebagai sarana pembelajaran yang interaktif dan menyenangkan.
PENINGKATAN KOMPETENSI MAHASISWA DEPARTEMEN ADMINISTRASI PENDIDIKAN MELALUI PROGRAM MAGANG DI MTS AL-ARAFAH
Authors: Bahrudin Canra
Published: December 2024

Program magang merupakan bagian terpenting pada aspek kurikulum pendidikan tinggi yang dirumuskan guna membekali kompetensi praktis mahasiswa, terutama pada bidang Administrasi Pendidikan. Pengabdian ini dilakukan untuk menganalisis efektivitas program magang dalam meningkatkan kompetensi mahasiswa Prodi Administrasi Pendidikan, Universitas Muhammadiyah Bogor Raya melalui praktik langsung di MTs Al-Arafah. Program magang ini terbagi dalam tiga tahap yang diselenggarakan secara bertahap dari semester dua hingga semester enam. Metode pelaksanaan magang meliputi tahap persiapan, pelaksanaan, pendampingan, dan evaluasi. Hasil magang menunjukkan peningkatan kompetensi teknis mahasiswa, khususnya dalam pengelolaan data peserta didik berbasis digital dengan penggunaan Google Form yang terhubung dengan Microsoft Excel. Selain itu, mahasiswa juga mengalami peningkatan kemampuan analisis, penyusunan laporan, dan keterampilan interpersonal melalui pendampingan oleh dosen pembimbing. Program ini tidak hanya memberikan pengalaman langsung di dunia kerja, tetapi juga mempersiapkan mahasiswa untuk menghadapi tantangan di bidang administrasi pendidikan yang akan datang. Kesimpulan menunjukkan bahwa program magang ini efektif dalam membentuk kompetensi mahasiswa, meskipun perlu untuk dilakukan pengembangan berkelanjutan pada produk digital yang dihasilkan untuk memenuhi kebutuhan sekolah secara optimal.
PENDAMPINGAN PERSIAPAN OLIMPIADE SAINS NASIONAL MATEMATIKA SMA TARAKANITA MAGELANG
Authors: Purwadi Joko , Haryono Nugroho Agus , Santosa Gunawan , Jong Jek Siang
Published: December 2024

Sekolah Menengah Atas (SMA) Tarakanita Magelang adalah salah satu SMA swasta di kota Magelang, Jawa Tengah yang berdiri sejak tahun 1984. Permasalahan yang dihadapi SMA Tarakanita adalah kurangnya tenaga pengajar yang dapat melatih siswa mempersiapkan diri mengikuti OSN bidang matematika tahun 2024. Kegiatan pengabdian masyarakat bertujuan untuk membantu siswa SMA Tarakanita Magelang dalam mempersiapkan diri menghadapi OSN Matematika. Pendampingan diikuti oleh 8 siswa kelas 10 dan 11 yang disetujui sekolah untuk mengikuti OSN MAtematika. Metode pelaksanaan kegiatan meliputi: koordinasi teknis kegiatan bersama wakil kepala sekolah dan guru matematika, pendampingan persiapan OSN Matematika berupa pengerjaan dan pembahasan latihan soal, serta evaluasi bersama guru dan siswa SMA Tarakanita Magelang. Rangkaian kegiatan dilakukan pada bulan Nopember 2023 – April 2024. Evaluasi keberhasilan kegiatan dilakukan di akhir pendampingan terhadap 5 siswa yang aktif mengikuti kegiatan hingga akhir dan 2 guru pendamping menggunakan Gform. Hasilnya menunjukkan nilai 4,75 (guru) dan 4,58 (siswa) dalam skala 1 (sangat buruk) hingga 5 (sangat baik). Hasil ini menunjukkan bahwa pelaksanaan pengabdian sudah sangat baik. Hasil ini juga diperkuat dengan masukan guru secara verbal di akhir kegiatan yang mengharapkan kegiatan serupa dilakukan lagi untuk tahun 2025
PENDAMPINGAN EVALUASI KERJA TENAGA KEPENDIDIKAN MELALUI PELATIHAN LITERASI TEKNOLOGI PERKANTORAN
Authors: Antonius Rachmat Chrismanto  , Wibowo Argo , Halim Budi Santoso  , Katon Wijana
Published: December 2024

Peran tenaga kependidikan dalam institusi pendidikan sangat penting karena tenaga kependidikan membantu mengerjakan urusan administrasi.  Kemajuan teknologi, contohnya Microsoft Office 365, menawarkan sarana kepada para tenaga kependidikan untuk menyederhanakan tugas administratif secara efisien. Aplikasi Microsoft Office 365 memiliki fungsionalitas yang disesuaikan untuk mendorong alur kerja administratif, memungkinkan tenaga kependidikan untuk memprioritaskan pengalaman belajar siswa.  Tenaga kependidikan di SMA BOPKRI 1 Yogyakarta percaya bahwa memanfaatkan teknologi dapat menyeimbangkan tugas pengajaran dan administrasi. Melalui kerjasama dengan FTI UKDW, dilakukan kegiatan pengabdian masyarakat bertujuan untuk memberikan pendampingan kepada tenaga kependidikan dan karyawan dalam memahami dan menerapkan fitur aplikasi Microsoft Office 365 sabagai sarana evaluasi kinerja. Pelatihan mencakup tiga aplikasi utama: MS Word, MS PowerPoint, dan MS Excel, serta Canva sebagai alternatif untuk presentasi. Kegiatan ini telah dilaksanakan sesuai rencana, meskipun ada kendala dalam penyesuaian jadwal pelatihan. Pelatihan yang dilakukan pada hari dan jam kerja menghambat partisipasi optimal, sehingga disarankan untuk dilakukan saat libur antar semester atau libur kenaikan kelas. Modul pelatihan telah disesuaikan dengan kebutuhan sekolah, dan hasil pelaksanaan menunjukkan peningkatan kemampuan administrasi pegawai. Dari hasil pelatihan dapat digunakan sebagai sarana untuk melakukan evaluasi tenaga kependidikan di bidang literasi teknologi informasi.
A social realist analysis of the professional identity formation of lecturers emerging from completing professional development at a South African research-intensive university
Authors:   , Adams Anthea
Published: December 2024

This doctoral study is part of a Department of Higher Education and Training (DHET) capacity development project, Phakamisa. Using Margaret Archer's Social Realism as a substantive theory and methodological tool and Roy Bhaskar's Critical Realism as a meta-theory, I was able to identify and explain the interplay between the structural, cultural and agential mechanisms within a professional development course that enabled or constrained the emergence of lecturers' professional academic identities. My research participants are fourteen lecturers who completed the Postgraduate Diploma in Higher Education (PGDip HE) at Rhodes University between 2007 and 2017. Social Realism's explanatory methodologies, analytical dualism, and the morphogenetic cycle allowed me to provide causal explanations and account for the historicity of the emergence of lecturers' professional academic identities as teachers. A qualitative research design involving case study research allowed me to search for generative mechanisms to understand and explain the conditioning influence of often unobservable phenomena and underlying mechanisms in developing lecturers' identities as teachers in a research-intensive university. As strong social actors imbued with power and material resources, university leadership should consider the constraining influence of contextual conditions, such as the hegemony of disciplinary research versus research in the Scholarship of Teaching and Learning (SoTL). The socio-cultural (S-C) interactions of the fourteen lecturers (agents) signal the possibilities for structural, cultural and agential morphogenesis when agents choose to exercise their agency, i.e., their personal emergent properties (PEPs) to mediate prevalent structural and cultural emergent properties (SEPs and CEPs) enabling or constraining their personal projects. Lecturers' personal projects are the courses of action they intentionally engage in as they strive to establish sustainable yet evolving practices as teachers in their disciplines. This thesis shows that exercising their PEPs involves subjective reflexivity and transforming from primary agents to corporate agents due to collective action and alliances with like-minded peers and colleagues to shape the teaching and learning agenda in their respective departments and the broader higher education context. Triple morphogenesis of lecturers' agency occurred through their realisation as social actors. It signified the formation of their professional identities as teachers and how they uniquely embodied and enacted their teacher roles.
Teachers’ use of authentic tasks through mathematics trails in a mobile learning environment to facilitate conceptual teaching
Authors:   , Matengu Given Kahale
Published: December 2024

The teaching and learning of mathematics in Namibia is confronted by various forms of challenges that require continuous search for effective pedagogical strategies and approaches to enhance mathematical understanding. Some of the ways include using real and authentic outdoor activities and technological tools, such as smartphones, for teaching and learning purposes. The need to use authentic and realistic tasks in outdoor settings in the teaching of mathematics has strong support from the literature. Moreover, many recent reforms in education challenge teachers across all subjects to use modern and up-to-date technologies to complement and support existing approaches to teaching. Smartphones, in particular, offer new opportunities in the evolution of technology-enhanced learning by allowing teaching and learning to occur in authentic and realistic contexts that extend to real-life environments. This qualitative case study proposes a practical framework that can facilitate mathematical understanding in teaching through the implementation of authentic and realistic outdoor tasks by using the Math City Map (MCM) project on a smartphone. The study aims to analyse and understand how mathematics teachers can create and implement authentic and realistic tasks in an outdoor mathematics trail to facilitate the conceptual teaching of area, volume, ratio and proportion topics, within the context of the Realistic Mathematics Education theory (RME). The study is framed within the RME theory and the iPAC (personalisation, authenticity, collaboration) mobile pedagogical framework. The research process is underpinned by an interpretivist paradigm. Data was collected from eight selected teachers through observations and interviews and analysed using frameworks derived from the RME and iPAC mobile pedagogical theories and the emergence of common themes. The findings suggest that the integration of smartphones and mathematics trails have pedagogical benefits in mathematics teaching and can facilitate the use of outdoor tasks that are connected to learners’ realities. The study argues that while MCM mathematics trail tasks can be difficult to create, it was worthwhile for teachers using them to conceptually teach the selected topics. It is therefore hoped that the findings of this study contribute towards the use of outdoor mathematics trails and smartphones in the teaching of mathematics.
Protecting stateless children in South Africa through nationality: a children’s rights approach
Authors:   , Maziya Nokwanda Takalanga
Published: December 2024

This study investigates the role of nationality in protecting stateless children. Under interna-tional human rights law, all individuals, including stateless persons, are entitled to certain rights by virtue of being human. Consequently, stateless children should theoretically have access to fundamental rights such as education, healthcare, and social security, even without nationality. However, this study challenges the assumption that stateless children can access these rights merely because they are human. The study reveals that, in practice, stateless chil-dren struggle to access essential rights like education, healthcare, and social welfare without nationality. The study asserts that nationality is crucial for stateless children to access basic rights in South Africa. The study examines various treaties related to nationality and con-cludes that none impose a binding obligation on South Africa to confer nationality on state-less children. The study then draws on international children's rights principles such as the best interest of the child, the right to life, survival and development, and the right to non-discrimination to demonstrate that despite a clear obligation on South Africa in terms of trea-ty law to grant nationality to stateless, these principles, place limits on South Africa's exer-cise of sovereign power. This, in turn, makes way for granting nationality to stateless chil-dren.
Understanding the impact of narcissism and schadenfreude on e-consumers’ purchase of counterfeit pro-environmental goods
Authors:   Applied College, Jazan University, Jazan, Saudi Arabia, Manna Yahya
Published: December 2024

This study examines the connection between schadenfreude, personality traits (narcissism and jealousy), and e-consumers' purchase intentions toward counterfeit products in a GCC nation, specifically Saudi Arabia. It aims to understand how these personality traits and schadenfreude affect the likelihood of purchasing counterfeit sustainable products online. A quantitative cross-sectional design was used, with data collected from 309 e-consumers via an online survey. Stratified random sampling ensured diverse representation among participants. Structural equation modeling (SEM) was applied to analyze the data using SPSS 25 and AMOS 24 software for thorough statistical examination. The results indicate that personality traits, such as narcissism and jealousy, significantly predict schadenfreude among e-consumers. Furthermore, schadenfreude has a direct influence on their intentions to buy counterfeit sustainable products. The study also reveals that these negative personality traits heighten the impact of schadenfreude on purchase intentions, demonstrating a complex interaction between personality and emotional factors in consumer behavior. This research is one of the first to explore the relationship between personality traits, schadenfreude, and purchase intentions in e-commerce within a GCC nation. Its findings offer valuable insights for marketers and policymakers on how dark personality traits can shape sustainable consumption behaviors, helping them better promote sustainable products in the region.
Application of Clinical Department–Specific AI-Assisted Coding Using Taiwan Diagnosis-Related Groups: Retrospective Validation Study
Authors: Lu An-Tai , Liou Chong-Sin , Lai Chia-Hsin , Shian Bo-Tsz , Li Ming-Ta , Sun Chih-Yen , Kao Hao-Yun , Dai Hong-Jie , Tsai Ming-Ju
Published: December 2024

Background

The accuracy of the ICD-10-CM (International Classification of Diseases, Tenth Revision, Clinical Modification) procedure coding system (PCS) is crucial for generating correct Taiwan diagnosis-related groups (DRGs), as coding errors can lead to financial losses for hospitals.

Objective

The study aimed to determine the consistency between an artificial intelligence (AI)-assisted coding module and manual coding, as well as to identify clinical specialties suitable for implementing the developed AI-assisted coding module.

Methods

This study examined the AI-assisted coding module from the perspective of health care professionals. The research period started in February 2023. The study excluded cases outside of Taiwan DRGs, those with incomplete medical records, and cases with Taiwan DRG disposals ICD-10 (International Statistical Classification of Diseases, Tenth Revision) PCS. Data collection was conducted through retrospective medical record review. The AI-assisted module was constructed using a hierarchical attention network. The verification of the Taiwan DRGs results from the AI-assisted coding model focused on the major diagnostic categories (MDCs). Statistical computations were conducted using SPSS version 19. Research variables consisted of categorical variables represented by MDC, and continuous variables were represented by the relative weight of Taiwan DRGs.

Results

A total of 2632 discharge records meeting the research criteria were collected from February to April 2023. In terms of inferential statistics, κ statistics were used for MDC analysis. The infectious and parasitic diseases MDC, as well as the respiratory diseases MDC had κ values exceeding 0.8. Clinical inpatient specialties were statistically analyzed using the Wilcoxon signed rank test. There was not a difference in coding results between the 23 clinical departments, such as the Division of Cardiology, the Division of Nephrology, and the Department of Urology.

Conclusions

For human coders, with the assistance of the ICD-10-CM AI-assisted coding system, work time is reduced. Additionally, strengthening knowledge in clinical documentation enables human coders to maximize their role. This positions them to become clinical documentation experts, preparing them for further career development. Future research will apply the same method to validate the ICD-10 AI-assisted coding module.
Acceptance of Unsupervised App-Based Cognitive Assessment in Outpatient Care: An Implementation Study
Authors: Blotenberg Iris , Boekholt Melanie , Lieberknecht Nils , Säring Paula , Thyrian Jochen René
Published: December 2024

Background

The use of unsupervised digital cognitive assessments provides considerable opportunities for early and comprehensive testing for Alzheimer disease, minimizing the demand on time and personnel resources in medical practices. However, the acceptance within health care has yet to be assessed.

Objective

In this implementation study, the acceptance of an app-based, repeated cognitive assessment for early symptoms of Alzheimer disease in the outpatient care setting from both physicians’ and patients’ perspectives was examined.

Methods

In total, 15 primary care practices participated, where patients with self- or relative-reported memory problems could be prescribed an app (neotivCare app [neotiv GmbH]) for comprehensive cognitive testing. Patients used the app to test their episodic memory function weekly for 12 weeks at home. After the testing period and the final consultation, physicians and patients received questionnaires to assess the app’s acceptance.

Results

We received completed questionnaires from physicians for 45 patients. In addition, we received 45 completed questionnaires from the patients themselves. The physicians reported that, for most patients, the app supported their decision-making in the diagnostic process (26/45, 58%). In addition, most physicians found the app’s information dependable (34/45, 76%) and felt more certain in their decisions (38/45, 84%). From the patients’ perspective, a majority felt thoroughly tested (34/45, 76%), and only a few considered the time commitment for the cognitive tests to be too burdensome (7/45, 16%). Furthermore, despite the weekly cognitive testing and the lengthy 12-week testing period, a majority of patients participated in all tests (39/54, 72%).

Conclusions

Our results indicate a high level of acceptance by physicians and patients, suggesting significant potential for the implementation of unsupervised digital cognitive assessments into routine health care. In the future, acceptance should be assessed in large-scale studies, with a particular focus on the impact on health care delivery and patient outcomes.
The Use and Design of mHealth apps for Chinese older adults: Systematic review of literature and mHealth apps (Preprint)
Authors: Liu Ben Chi-Pun , Leung Dion Sik Yee
Published: December 2024

BACKGROUND

There has been a significant growth in mobile health (mHealth) to enable individuals to access health information, assessments, and treatments for managing their health conditions and enhancing their quality of life. However, research on how Chinese older adults perceived and utilized mHealth technologies for aging in place is limited.

OBJECTIVE

The study aimed to identify the benefits mHealth technologies for older adults in Hong Kong and to explore factors that can maximize their use and positive experience of mHealth technologies.

METHODS

The study systematically reviewed the literature related to mHealth technologies and their utilization patterns among Chinese older adults and randomly selected six mHealth apps for critical review using the User Version of the Mobile Application Rating Scale (uMARS).

RESULTS

Eleven out of 2399 records from databases including Medline, BMJ Journals, CINAAHL, Emerald Insight and Google Scholars and 8 out of 110 mHealth apps were selected for review. Five key themes were identified from the systematic review, including ‘Benefits of using mHealth technologies’, ‘to use or not to use mobile applications’, ‘Trust and belief in mHealth technologies’, ‘Perceived usefulness and intention to use mHealth apps’, and ‘Variations of mHealth practices—mHealth with interactivity intervention’. The landscape study using uMARS also found that the multi-functionality of App 1 is essential for providing holistic care for older adults, providing them with a more thorough understanding of their health condition regarding eight vital signs, including blood pressure, body temperature, blood oxygen level, blood sugar level, weight, heart rate, step count, and sleeping hours, than other apps.

CONCLUSIONS

Due to the human resources shortage, mHealth technology is in great demand among older adults in Hong Kong as mHealth app is believed to be effective in promoting health consciousness and self-care among older adults because of its multiple functions. However, mHealth developers and operators should address the technical and ethical issues, for example, privacy and data security, equal and fair access to mHealth technologies, and accuracy and reliability of the sources of health information used in the mHealth app, when adopting this approach in their delivery of services to older persons and their families.
Deep Learning Model for Prediction of Dementia Severity based on EEG Signals
Authors: Al-Qazzaz Noor Kamal , Mohd Ali Sawal Hamid Bin , Ahmad Siti Anom
Published: December 2024

This study aimed to determine variations in the electroencephalograms (EEGs) of 15 individuals who were diagnosed with mild cognitive impairment (MCI) following stroke, 5 individuals suffering from vascular dementia (VD) and 15 healthy normal control (NC) individuals who performed a working memory task. Conventional filters including notch and bandpass filters were utilised to remove noise from the EEG data. The proposed method comprises computing the estimates of the attention entropy (AttEn), bubble entropy (BubbEn) and symbolic dynamic entropy (SyDyEn) of univariate data sequence features. The long short-term memory (LSTM) deep learning neural network was used to automatically classify dementia severity through noninvasive EEG-based recordings. The LSTM classification result with AttEn exceeds an average of 88.9% than BubbEn and SyDyEn, with classification results of 69.2% and 77.7%, respectively. The analysis of the brain EEG-based dementia severity dataset suggests that AttEn could potentially serve as a biomarker for detecting dementia severity. AttEn can capture relevant patterns and features in the EEG data and may be indicative of the severity of dementia with LSTM RNN to differentiate patients with VD, patients with MCI and NC individuals.
Monitoring Alkalinity and Hardness During Treatment of Different Water Types
Authors: AlRubaye Shahad F. , Al Haboubi Naseer A. , Al-Amili Hussein A. , Al-Allaq Aiman H. , Rzaij Dina R.
Published: December 2024

Alkalinity and hardness are crucial factors in water treatment procedures, such as electrocoagulation (EC) and traditional coagulation–flocculation. Two types of water were employed in this study to investigate the use of EC: river water and discarded reverse osmosis system water. With bipolar and monopolar aluminum electrodes, continuous flow tests were conducted to evaluate the effects of different parameters on the variations in alkalinity and hardness versus time. The examined factors were flow rate (600 and 1,000 L/h) and number of electrodes (2 and 4). Polarity reversal was also studied. The water passed through the plates in a zigzag pattern. Results showed that the hardness under all operating conditions decreased with time, and alkalinity exhibited an oscillating behaviour. The ideal hardness removal for treating river and concentrated water was obtained using four plates with polarity reversal and a flow rate of 1,000 L/h, which were equal to 37.5% and 33.3%, respectively.
An Improved Prosthesis for Through Ankle Joint Amputation
Authors: Kadom Rasheed Noon , Kahtan Yassr Y.
Published: December 2024

يتميز الطرف الاصطناعي بالعديد من الوظائف منها أنه يستبدل الجزء المفقود نتيجة حروب سابقة أو أمراض أو أسباب أخرى أدت إلى بتر الطرف ، لذلك عند استبدال الجزء المبتور يجب أن يوفر الوظيفة التي تم فقدها أيضًا ، حتى يتمكن المبتور من قبول هذا الجزء الغريب الذي يلتصق به كجزء من أجزاء جسمه ، لذلك نسعى لتحسين وتقوية الطرف الاصطناعي إلى مستوى البتر من خلال مفصل الكاحل من خلال تعزيز الحركات التي تساعد في المشي على أرض مستوية أو منحدرة أو على التضاريس ، وأهمها حركات الانقلاب للداخل والخارج ، وقد تم تصميم المفصل باستخدام برنامج SOLIDWORK وتحليله باستخدام برنامج ANSYS وتنفيذه بشكل واقعي عند الاقتناع. مريض مبتور
Fingerprint-Authenticated Voting System with Real- Time Data Sharing via Android Application
Authors: Prajapati Ankit , Patel Roshani , Pundpal Vineet , Karia Prof. Deepak
Published: December 2024

Abstract: This system presents a novel electronic voting solution tailored for college-level elections, integrating biometric
authentication with real-time data transmission. The system is built around an ESP32 microcontroller, a fingerprint sensor for
secure user authentication, and an OLED display for interaction. Upon successful authentication, the ESP32 activates Bluetooth
to connect seamlessly with an Android application, providing users with a simple interface for voting, polling, or submitting
feedback. This system improves security and transparency by ensuring only authorized individuals can vote, while real-time data
transmission fosters immediate result processing and accountability. By combining biometric security, ease of use, and
instantaneous communication, the system promotes an inclusive and participatory governance environment within educational
institutions
Comparison of Clinical Symptoms and Laboratory Findings in Typhoid Fever and Dengue Fever Patients
Authors: Nurhayati
Published: December 2024

Abstract: Background: Typhoid fever and dengue hemorrhagic fever (DHF) are two infections that often occur in tropical and
subtropical areas, including Indonesia, with similar clinical symptoms but different pathogens. Accurate diagnosis is essential
for proper management.
Objective: This study aims to analyze the differences in clinical symptoms and laboratory findings in typhoid fever and dengue
fever patients at Aek Kanopan Regional Hospital, North Labuhan Batu Regency, North Sumatra.
Method: This research is an observational comparative study involving 100 patients diagnosed with typhoid fever and dengue
fever during the period December 2023 to February 2024. Data on clinical symptoms and laboratory examination results were
collected and analyzed using descriptive and inferential statistics.
Results: Results show that symptoms of stomach ache and headache are more common in typhoid fever patients, while rash and
muscle pain are more prevalent in dengue fever patients. From a laboratory perspective, typhoid fever patients have an increased
number of leukocytes (12,000 ± 3,500 cells/µL) compared to dengue fever (9,000 ± 2,000 cells/µL), while platelets in dengue
fever patients are on average lower (45,000 ± 15,000 cells/µL) compared to typhoid fever (75,000 ± 20,000 cells/µL).
Conclusion: This study confirms the importance of understanding the clinical and laboratory differences between typhoid fever
and dengue fever to improve the accuracy of diagnosis and patient management. These results contribute to the development of
better clinical guidelines for managing febrile infections in areas with high prevalence.
Implementation of Site to Site IPsec VPN Tunnel using GNS3 Simulation
Authors: Hadood Ashraf Khalifa M.
Published: December 2024

Abstract: This paper focuses on the implementation of a site-to-site IPsec tunnel to establish a secure connected link over a
public network between two sites. To do so, an IP addressing plan was created and a topology was drawn to replicate a local area
network between different sites, i.e., LIBYA and TUNIS. After this, an IP tunnel was set up, secure communication was
established in the replicating LAN, and all packets were transferred over an encrypted form between the two different sites
correctly.
The area of this study lies in the domains of network security and VPN. When discussing the technicalities, for this research, we
will establish an IP tunneling over an encryption layer. For this task, we will implement the Internet Protocol Security (IPsec)
suite to authenticate and encrypt the traffic before encapsulating the actual payloads for the connected link on the OSI model
Layer 3. After setting the required authentication and encryption methods over the connections, a secure link can be established
to share the data neighborly in a public environment. A secure VPN site-to-site link will provide high-quality dedicated
bandwidth WAN links to the users, which are considered significant for the network architecture of internetworking. As a result,
secure communication features utilizing VPN site-to-site IPsec encryption play a vital role in disaster recovery between the
different sites or the replication of services and data for business operations and communications. This paper recommends that it
is essential for a growing organization to make their respective communication secure and implement alternative ways to
manage, maintain, and control the secure communication environments.
Evaluating the Impact of Various Existing Computer Vision Models on Reducing False Negatives and Positives in Commercial and Residential Security Surveillance Systems
Authors: Balamurugan Harish , Pakanati Pranav , Amara Vedh
Published: December 2024

Abstract: The following analytical study examines the contributions different computer vision models have made to reduce false
negatives and positives in surveillance systems. Synthesizing the results of existing research regarding models in different
environmental conditions, the work further compares the implications of these technologies at commercial and residential levels.
The contexts of environmental and operational variances are tested apart to find any resultant trends and/or challenges.
Conclusions are then derived from these results to recommend specific models that would perform better in a residential or
commercial setting. Limitations are observed and results are discussed in a larger multi-disciplinary context.
Multiphysics Analysis of Convergent-Divergent nozzle using FGM
Authors: Mathur Sahil , Singh Rahul
Published: December 2024

Abstract: The study focuses on the Convergent-Divergent nozzle for the different types of flow regions and Mach numbers such
as subsonic region, sonic region and supersonic region. The Mach number of the nozzle changes across the nozzle, the Mach
number varies from the subsonic region at the inlet and varies to the supersonic region at the exhaust of the nozzle. The fluid
domain is made across the nozzle to capture the effects of the pressure and temperature and Multi physics analysis is also done
to find the deformation depending on the material. The multi-physics analysis of the nozzle is done in COMSOL Multiphysics
software by using the system coupling of the turbulent model, solid mechanics and heat transfer models. The results show the
deformation of the nozzle under the action of chamber pressure and chamber temperature as the nozzle is the crucial part of any
rocket or jet engine of an aircraft or rocket or launch vehicle. The Convergent-Divergent nozzle first converges the flow from the
combustion chamber and then diverges the flow to get the maximum thrust at the convergent section the pressure of the fuel
increases and then at the exhaust or convergent section suddenly increases enhances the thrust and velocity of the coming the
exhaust fuel.