bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing a calcium alginate dressing for venous ulcers of the leg
Authors: Moffatt C. J. , Oldroyd M. I. , Franks P. J.
Published: December 2016

A small study of Tegagel calcium alginate dressings is described, with a discussion of the methodology employed
Healing effect of human trophoblast on indolent wounds
Authors: Beaconsfield T. , Genbacev O. , Taylor R.S. , Micic S.
Published: December 2016

This study reports on the results of a trial in which the cytosol extract of trophoblast obtained from legal abortions was used for the treatment of indolent leg ulcers and severe chronic cystitis caused by irradiation therapy
The epidemiology of two common age-related wounds
Authors: Fletcher A.
Published: December 2016

A consideration of methodological issues and problems in the epidemiology of wound management of elderly people
From the Journals
Authors: Evans W. , Bretland A. , Hiscox S.J. , Chant D.
Published: December 2016

The effects of adenosine nucleotides on the repair process

Problems in tissue repair response

The prevalence of lower-limb ulceration

The development of tissue engineering

Ontogenesis of the basement membrane
Managing a patient with an infected foot ulcer
Authors: Hollinworth H.
Published: December 2016

The care of a patient whose foot had become infected with gas gangrene is described
Cavity wound management
Authors: Berry D.P. , Jones V.
Published: December 2016

A guide to patient assessment, wound classification and dressing choice in the management of cavity wounds
Letters
Authors: James P.B. , Allen M.W. , Bale S. , Banks V. , Peel K. , Shaw E. , Humzah M.D. , McRobbie D.
Published: December 2016

SYSTEMIC HYPERBARIC OXYGEN THERAPY

HYPOCHLORITE SOLUTIONS
Management of burns
Authors: Arturson G.
Published: December 2016

A review of the priorities of care during the acute management of burnt patients
Reviews
Authors: Lane C. , Pope S. A. , Smith K. , Spooner R.
Published: December 2016

FORMULARY OF WOUND MANAGEMENT PRODUCTS (Fifth edition)

THE WOUND PROGRAMME

UNDERSTANDING WHY: MOIST WOUND HEALING

PRESSURE SORES: VIDEO LECTURES
A new treatment for leg ulcers
Authors: Llewellyn M. , Whiston R.J. , Melhuish J.
Published: December 2016

A new treatment for leg ulcers
Treating a patient with a heavily exuding malodorous fungating ulcer
Authors: Boardman M. , Mellor K. , Neville B.
Published: December 2016

The palliative care of a terminally ill patient and the steps taken to improve his quality of life are described
Letters
Authors: Franks P.I. , Keachie J.
Published: December 2016

CLINICAL TRIALS OF DRESSINGS

A CHEAPER ALTERNATIVE TO THE FOUR-LAYER BANDAGE SYSTEM
Managing a patient's multiple pressure sores
Authors: Spooner R.
Published: December 2016

The care of an elderly woman with little mobility, dementia and several pressure sores is reviewed
Care of a patient with an infected ulcer of the foot
Authors: Benbow M.E.
Published: December 2016

The treatment of a patient whose case was complicated by diabetes mellitus is examined
A pressure sore in an infant
Authors: Kumar K.A. , Kumar E.
Published: December 2016

The development of a pressure ulcer in an eight-month-old infant is discussed
Foam dressings
Authors: Thomas S.
Published: December 2016

A guide to the properties and uses of the main foam dressings available in the UK
Examining the properties and uses of two hydrogel sheet dressings
Authors: Thomas S. , Loveless P.
Published: December 2016

The purpose of this study was to review the physical characteristics and fluid-handling properties of two hydrogel sheet dressings in order to determine whether these materials possess any unique features which make them especially well suited to the treatment of specific types of problem wounds
Reviews
Authors: Spooner R. , Ruckley C. V. , Nott D.M. , Lane C. M.
Published: December 2016

THE MANAGEMENT OF WOUNDS AND BURNS

CHRONIC VENOUS DISEASES OF THE LEG

FRAUD AND MISCONDUCT IN MEDICAL RESEARCH

PSYCHOLOGY, PSYCHIATRY AND CHRONIC PAIN
Letters
Authors: Davidson Linda , Bourne I.H.J. , Wilson P. , Hedges J.
Published: December 2016

IRRIGATION OF WOUNDS

OEDEMA AND LEG ULCERS

PREPARING WOUND SAMPLES FOR ANALYSIS

EDUCATION NEEDED
From the Journals
Authors: Jones V. , Jones R. , Roberts G.P.
Published: December 2016

Prevalence of pressure sores

Aromatherapy in wound care

Fibronectin and vitronectin degradation
Predicting pressure sore risk
Authors: Flanagan M.
Published: December 2016

A guide to the risk factors identified in the most common pressure sore risk assessment scales in use
Reviews
Authors: Eyre G. , Benbow M. , Cochran C. L.
Published: December 2016

FIRST AID MANUAL (6th edn)

EPIDEMIOLOGY FOR THE UNINITIATED (3rd edn)

THE NURSING MANAGEMENT OF VENOUS ULCERS

FOCUS ON PRESSURE SORES
Drug Monographs: Atezolizumab and Everolimus
Authors: Green Matthew A. , Waddell J. Aubrey , Solimando Dominic A.
Published: December 2016

The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases.
Implementation of a Pharmacist-Directed Antimicrobial Stewardship Protocol Utilizing Rapid Diagnostic Testing
Authors: Heyerly Angel , Jones Ron , Bokhart Gordon , Shoaff Mary , Fisher Douglas
Published: December 2016

Background

Rapid identification of gram-positive bacteria and resistance determinants from blood cultures can reduce the time to optimal antibiotic therapy.

Objective

This study evaluates the use of technology to rapidly identify gram-positive bacteria in combination with a pharmacist-directed antimicrobial stewardship protocol in a tertiary-care facility.

Methods

Rapid diagnostic testing was performed on gram-positive blood cultures. Pharmacists were instructed to notify prescribers of results and recommend appropriate antimicrobial therapy based on targeted treatment chart. The primary outcomes were mean time to optimal antibiotic therapy, mean time antibiotics were avoided before traditional culture results, and percent of patients with time to optimal antibiotic therapy reached in less than or equal to 2 hours.

Results

Inclusion criteria were met for 297 patients. Mean time to identify bacteria was 26.8 hours with nucleic acid assay versus 75.3 hours with traditional culture (difference = 48.5 hours, p < .0001). The rapid identification of gram-positive bacteria combined with accepted pharmacist intervention improved time to optimal antibiotic therapy (8.4 vs 15.4 hours, p = .0095). When contaminants were identified, antibiotics were avoided for 39.5 hours before traditional culture with pharmacist intervention versus 37.2 hours ( p > .05). Antibiotic change occurred in less than or equal to 2 hours in more patients in the pharmacist intervention group (28% vs 10.5%, p = .0002).

Conclusions

Rapid identification combined with pharmacist intervention significantly improved time to optimal antibiotic therapy and significantly increased the number of patients receiving optimal antibiotic therapy in less than or equal to 2 hours over rapid identification alone. A pharmacist-directed protocol combined with rapid identification enhanced antimicrobial stewardship.
Impact of the FDA Warning for Azithromycin and Risk for QT Prolongation on Utilization at an Academic Medical Center
Authors: Dunker Abby , Kolanczyk Denise M. , Maendel Caitlin M. , Patel Amit R. , Pettit Natasha N.
Published: December 2016

A US Food and Drug Administration (FDA) drug safety communication was released in March 2013, warning prescribers of the risk of QT prolongation associated with azithromycin. Overall azithromycin utilization and adherence to an inpatient QTc monitoring guideline during 8-month time periods before and after the warning were assessed to evaluate the impact of this warning on inpatient azithromycin utilization and QTc monitoring. Fifty-five patients were included in the prewarning time period and 50 were included in the postwarning period. A significant reduction in utilization in days of therapy per 1,000 patient days was observed (31.2 prewarning vs 17.5 postwarning, p < .001) in these groups. No changes in QTc monitoring among patients receiving azithromycin were identified. FDA warnings of severe, life-threatening toxicities can have a profound impact on utilization and prescribing of medications, however they may not necessarily change monitoring practices.
Does Your Department Have a Technology Innovation Strategy?
Authors: Felkey Bill G. , Fox Brent I.
Published: December 2016

There are ways to facilitate the successful implementation of technological innovations. These are especially important in a time of rapid development of new tools to support safe and effective medication therapy. This installment addresses some of the key components of a successful technology innovation strategy.
The association between febrile convulsion in children and chronic hyperventilation in parents
Authors: Samekto M. Widiastuti , Ardana I Gusti Putu
Published: November 2016

Background Febrile convulsion and chronic hyperventilation syndrome (spasmophilia) are suspected to share the same root of pathophysiology, a genetic trait abnormality related to ion channel that could cause neuronal hyperexcitability.Objective To determine the prevalence ratio of parents with chronic hyperventilation syndrome between two groups of children with and without febrile convulsion.Methods A cross-sectional design study was used, with a tertiary hospital setting (Kariadi Hospital). Participants were selected consecutively based on eligibility criteria. Febrile convulsion was diagnosed based on a modified Livingstone criteria. Chronic hyperventilation syndrome in parents was determined using the clinical diagnostic test of spasmophilia (88.4% sensitivity and 6 1.6% specificity). Statistical calculations were conducted with two by two table analysis and within the 95% confidence interval.Results Sixty-two children (mean age 18 months) who met the eligibility criteria were included. The parents' mean ages were 33 years (father) and 29 years (mother). The prevalence ratio of father, mother and both parents with chronic hyperventilation between the febrile convulsion group and the non-febrile convulsion group were 2.56 (95% CI 0.53 to 12.31), 6.19 (95% CI 1.70 to 22.6) and 18.7 (95% CI3.07 to 113.9), respectively.Conclusion Febrile convulsion can be anticipated in children of parents who suffer from chronic hyperventilation syndrome.
„Treiben wir oder werden wir getrieben“ – Wissenschaftliche Bibliotheken im Wandel
Authors: Neuhausen Hubertus
Published: December 2016

Der vorliegende Beitrag versucht zu zeigen, dass sich die Frage, ob die wissenschaftlichen Bibliotheken den Wandel gestalten oder von ihm getrieben werden, ohne weiteres dahingehend beantworten lässt, dass wir, die wissenschaftlichen Bibliotheken, von einer Reihe von Entwicklungen getrieben werden, die im Folgenden vorgestellt werden. Allerdings laufen wir auf Grund unseres Binnenerlebens in den Bibliotheken Gefahr, gar nicht wahrzunehmen, wie stark der Veränderungsdruck von außen ist. Infolgedessen steht zu befürchten, den Anschluss an die „Welt um uns herum“ zu verlieren und nicht mehr als relevante Einrichtungen wahrgenommen zu werden. Für die Zukunft der wissenschaftlichen Bibliotheken wird es ausschlaggebend sein, dass sie angemessene Antworten auf die beschriebenen Entwicklungen finden und sich als Serviceeinrichtungen profilieren, die einen kleinen, aber wesentlichen Beitrag zum Erfolg der Hochschulen beitragen, zu denen sie gehören.
GA based optimal planning of VAR sources using Fast Voltage Stability Index method
Authors: Bhattacharyya Biplab , Rani Shweta , Vais Ram Ishwar , Bharti Indradeo Pratap
Published: November 2016

This paper presents a novel approach for reactive power planning of a connected power network. Reactive power planning is nothing but the optimal usage of all reactive power sources i.e., transformer tap setting arrangements, reactive generations of generators and shunt VAR compensators installed at weak nodes. Shunt VAR compensator placement positions are determined by a FVSI (Fast Voltage Stability Index) method. Optimal setting of all reactive power reserves are determined by a GA (genetic algorithm) based optimization method. The effectiveness of the detection of the weak nodes by the FVSI method is validated by comparing the result with two other wellknown methods of weak node detection like Modal analysis and the L-index method. Finally, FVSI based allocation of VAR sources emerges as the most suitable method for reactive power planning.
A closed-loop power controller model of series-resonant-inverter-fitted induction heating system
Authors: Pal Palash , Roy Debabrata , Datta Avik , Sadhu Pradip K. , Banerjee Atanu
Published: November 2016

This paper presents a mathematical model of a power controller for a high-frequency induction heating system based on a modified half-bridge series resonant inverter. The output real power is precise over the heating coil, and this real power is processed as a feedback signal that contends a closed-loop topology with a proportional-integral-derivative controller. This technique enables both control of the closed-loop power and determination of the stability of the high-frequency inverter. Unlike the topologies of existing power controllers, the proposed topology enables direct control of the real power of the high-frequency inverter.
An elliptic equation with an indefinite sublinear boundary condition
Authors: Ramos Quoirin Humberto , Umezu Kenichiro
Published: December 2016

We investigate the problem

{

-

Δ
⁢
u

=

|
u
|

p
-
2

⁢
u

in 
Ω

,

∂
⁡
u

∂
⁡
𝐧

=

λ
⁢
b
⁢

(
x
)

⁢

|
u
|

q
-
2

⁢
u

on 

∂
⁡
Ω

,

\left\{\begin{aligned} \displaystyle-\Delta u&\displaystyle=\lvert u\rvert^{p-%
2}u&&\displaystyle\phantom{}\text{in ${\Omega}$},\\
\displaystyle\frac{\partial u}{\partial\mathbf{n}}&\displaystyle=\lambda b(x)%
\lvert u\rvert^{q-2}u&&\displaystyle\phantom{}\text{on ${\partial\Omega}$},%
\end{aligned}\right.

where Ω is a bounded and smooth domain of

ℝ
N

{\mathbb{R}^{N}}

(

N
≥
2

{N\geq 2}

),

1
<
q
<
2
<
p

{1<q<2

0

{\lambda>0}

, and

b
∈

C

1
+
α

⁢

(

∂
⁡
Ω

)

{b\in C^{1+\alpha}(\partial\Omega)}

for some

α
∈

(
0
,
1
)

{\alpha\in(0,1)}

. We show that

∫

∂
⁡
Ω

b

<
0

{\int_{\partial\Omega}b<0}

is a necessary and sufficient condition for the existence of nontrivial non-negative solutions of this problem. Under the additional condition

b
+

≢
0

{b^{+}\not\equiv 0}

we show that for

λ
>
0

{\lambda>0}

sufficiently small this problem has two nontrivial non-negative solutions which converge to zero in

C
⁢

(

Ω
¯

)

{C(\overline{\Omega})}

as

λ
→
0

{\lambda\to 0}

. When

p
<

2
*

{p<2^{*}}

we also provide the asymptotic profiles of these solutions.
Aufstiegsfortbildung und Karriere – Quo vadis?
Authors: Hall Anja
Published: December 2016

Das Verhältnis von beruflicher und akademischer Bildung hat sich im Zuge der Hochschulreform verschoben. Der vorliegende Beitrag analysiert für die Abschlusskohorten 2000-2005 und 2006-2011 jeweils maximal sechs Jahre nach ihrem Abschluss die Verwertungschancen beruflicher und akademischer Tertiärabschlüsse. Datenbasis sind die BIBB/BAuA-Erwerbstätigenbefragungen 2006 und 2012. Zur Abbildung der Verwertungschancen werden Lohnprämien (Bruttostundenlohn) und die beruflichen Positionen (hochqualifizierte Tätigkeiten) betrachtet. Angewendet werden lineare und logistische Regressionsmodelle auf Basis gepoolter Datensätze. Im betrachteten Zeitraum zeigen sich im Vergleich zu Personen mit dualer Berufsausbildung unverändert hohe Lohnprämien für Personen mit Aufstiegsfortbildung und sinkende Lohnprämien für Personen mit Bachelor- bzw. traditionellem FH-Abschluss.
Antioxidant activity as indicator of UV radiation and other abiotic stress factors on Agaricus bisporus (Lange/Imbach) and Sedum hybridum (L.)
Authors: Szabó A. , Geösel A. , Kókai Z. , Orbán Cs. , Töreki K. , Szőke A.
Published: November 2016

Investigation of stress level might be facilitated also in plant and horticultural sciences, but currently mainly morphological parameters are in use. Antioxidant activity routinely measured in food-oriented researches and several studies indirectly indicated that stress factors can influence this parameter. Our aim was to assess the potential direct indicator role of antioxidant activity in stress conditions. We measured the effects of UVB and soil-delivered stress on Agaricus bisporus and Sedum hybridum. Our results indicate that UVB slightly decreases, while the inadequate soil conditions increase antioxidant activity; hence these measurements are suitable for determining the level of stress in different living samples.
What to Do with Stories?
Authors: Bönisch-Brednich Brigitte
Published: November 2016

The rise and, moreover, the continuing ascent of
Das Märchenerzählen in Benin zwischen Tradition und Modernität
Authors: Tokponto Mensah Wekenon
Published: November 2016

Die afrikanische Oralliteratur zeichnet sich traditionell gesehen durch verschiedene Ausdrucksformen wie Sprichwörter, Volkslieder, Rätsel, Epen, Sagen, Mythen, Legenden und hauptsächlich durch das mündlich überlieferte Märchen aus. Unter diesen Ausdrucksformen, die im Allgemeinen als Gattungen der oralen Literatur bezeichnet werden, nahm das Märchen bei der Volksgruppe der Fon in Benin eine führende Stelle ein. Es wurde über Generationen hinweg in den Familien und speziell bei den Erzählabenden auf den Dorfplätzen durch professionelle Erzähler mündlich tradiert und gehörte als immaterielles Erbe der Vorfahren und aufgrund der von ihm vermittelten Werte zum Alltagsleben der Menschen. Der Beitrag zeigt in erster Linie, wie die Bestimmung des Begriffs Märchen bei den Fon für Verwirrung sorgt. Er verdeutlicht, wie sich das Märchen aus afrikanischer Perspektive nicht so scharf von den anderen Gattungen der Oralliteratur abhebt, wie es im europäischen Kontext der Fall ist. Ferner hebt diese Abhandlung hervor, wie das lange erhaltene, mündlich tradierte Märchenerzählen in den letzten Jahrzehnten in Benin große Veränderungen durchlaufen hat, und stellt die konkreten Hintergründe heraus, die diesem Umbruch zugrunde liegen. Zum Schluss lenkt sie das Augenmerk auf die Zukunft des Märchenerzählens in Benin.
Legislating for Same-Sex Marriage: Sophistical Effectiveness in Australian Law
Authors: Lilienthal Gary
Published: November 2016

This paper by-passes the various public tropes, such as “marriage equality”, and concentrates on determining whether or not a same-sex marriage law would be sophistically effective in Australia. It revives the ancient Greek sophistical rhetorical skill of proposing a law, and applies it as a critical context to the topic of legislating for same-sex marriage. The objective is to assess whether or not a same-sex marriage law will be effective in its legislative objects. It proposes to discuss whether the parliament could introduce such a law so that the law’s objects were achieved effectively in the public mind. Argument will try to show that introducing a law to create same-sex marriage would fail because of subsisting priestly legislation on the subject of marriage. Its two hypotheses are that the canon law and other English priestly legislation restrict the scope of marriage regulation, and marriage could not be re-defined to cover same-sex marriage. Sections of the paper examining the law historically employ the historiographical method of identifying underlying norms, the effect of which is occasional reverse chronologies. The article’s conclusion will assert that a statute for legal and duly registered same-sex marriage likely would be, according to sophistical rhetorical reasoning, a fiction misrepresenting the truth of the subsisting legal and social institutions of marriage.
Single- or Double-Bundle Technique in the Anterior Cruciate Ligament Reconstruction — Current Concepts and Review of the Literature
Authors: Fleaca Radu , Prejbeanu Radu , Feier Andrei-Marian , Russu Octav , Todor Adrian , Predescu Vlad , Codorean Bogdan , Bățagă Tiberiu , Roman Mihai
Published: November 2016

The treatment for anterior cruciate ligament (ACL) deficient knee consists in its surgical reconstruction. There are several available and validated techniques, but there are still numerous questions to be answered concerning the best approach in terms of stability, functional outcome, and avoiding further damage in the knee. This paper sought to analyze the studies published in the literature comparing the outcomes of ACL restoration with single-bundle versus double-bundle techniques. The results demonstrate that even if biomechanical studies find an increased steadiness with double-bundle ACL reconstruction, there seems to be no clinical or functional benefit compared with single-bundle reconstruction.
ACL Surgical Technique — Staying Out of Trouble
Authors: Predescu Vlad , Prejbeanu Radu , Bordea Robert , Todor Adrian , Codorean Bogdan , Roman Mihai , Fleaca Radu , Russu Octav , Bățagă Tiberiu , Deleanu Bogdan
Published: November 2016

The incidence of ACL tear and reconstruction has increased over time, and failure of ACL reconstruction is not perfectly defined among surgeons. Atraumatic failure of ACL surgery represents approximately 70% of causes, and occurs in diagnostic errors, technical errors and problems of ACL graft integrations. Regarding surgical technique, we should answer certain questions about our choice of surgery, tunnel position, graft type, graft suture, tensioning the graft, and how we deal with certain incidents or intraoperative accidents. The purpose of this article is to review the current information and trends of ACL reconstruction, and presents some tips and tricks we use in our current practice.
Christianity and Implicit Racism in the U.S.
Moral and Human Economy
Authors: Bae Bosco B.
Published: December 2016

The relationship between Christianity and racism in the United States has a long history. In an age
of ‘multiculturalism’ and ‘colour-blind’ ideology, explicit forms of racism have become less conspicuous.
Still, disparities arise across the country’s human economy, and explicit statements of egalitarianism
are incongruent with practices of discrimination in U.S. Christian churches. This article explores this
incongruence and the relationship between Christianity and implicit forms of racism. By discussing
theological individualism and the principle of ‘homophily’, the article contributes to discussions about
the relationship between the moral and human economy. Through this, a Christian morality of salvific
aspiration is translated into a morality of personal economic responsibility and duty.
Efficiency Play, Games, Competitions, Production – How to Analyze the Configurations of Sport?
Authors: Eichberg Henning
Published: December 2016

The comparative, differential phenomenology of play and games has a critical political point. A mainstream discourse identifies – more or less – sport with play and game and describes sport as just a modernized extension of play or as a universal phenomenon that has existed since the Stone Age or the ancient Greek Olympics. This may be problematical, as there was no sport before industrial modernity. Before 1800, people were involved in a richness of play and games, competitions, festivities, and dances, which to large extent have disappeared or were marginalized, suppressed, and replaced by sport. The established rhetoric of “ancient Greek sport”, “medieval tournament sport”, etc., can be questioned.

Configurational analysis as a procedure of differential phenomenology can help in analyzing sport as a specific modern game which produces objectified results through bodily movement. This analysis casts light not only on the phenomenon of sport itself, but also on the methodological and epistemological challenge of studying play, movement, and body culture.
Identifying the Main Problems of Environmental Non-Governmental Organisations: Lessons from Romania
Authors: Apostoaie Constantin-Marius , Ionce Ruxandra
Published: December 2016

Romanian environmental non-governmental organisations (ENGO) have to deal with a lot of issues when performing their activities, related in general to their form of organization, financial capacity, unspecialized workforce, over bureaucratic administration, political parties’ unwillingness to cooperate, or mass-media’s general indifference. Moreover, most public representatives (e.g., political parties) seldom (or never) ask for the ENGOs’ opinions when designing environmental policies. Within this context, this paper aims to map the most important issues or challenges (in terms of financial capacity and with regard to the public sphere) that Romanian ENGOs have to deal with. The methodological approach is a mixed one (having a qualitative as well as a quantitative component). The study embodies a questionnaire based survey applied on 48 Romanian ENGOs. Unfortunately, the instability of financial resources still tops the Romanian ENGOs’ list of issues. Moreover, the data reaffirmed the indifference of the majority of Romania’s political parties towards protecting the environment (leaving ENGOs out of the political decision making process).
Economic and Geografical Aspects of Water Use in the Prut River Basin (The sector of the Republic of Moldova)
Authors: Petru Bacal
Published: December 2016

The purpose of this research consists in the elucidation of spatial and economic aspects of the water use in the Prut river basin. The main topics presented in this paper are: 1) the dynamics of water use; 2) spatial and branch profile of water use and its dynamics: 3) existing problems in the evaluation and monitoring of water use; 5) efficiency of the implementation of economic instruments of water management. To achieve these objectives were used traditional methods of geographical and economic research. Also, the content of the present study is focused on the methodology to elaborate the management plans of hydrographical basins and their chapters on the status of water resources and water bodies and on economic analysis of water use in the Prut river basin.
Criteria for Climate and Weather Related Risks Identification over the Republic of Moldova Territory
Authors: Nedealcov Maria
Published: December 2016

The accelerating pace of climate change is associated to weather-climate related risks manifestations, which in recent years are becoming more intensive and more frequent. Unfortunately, we find that far at regional level there are no a basic scientific information which could highlight their specific spatio-temporal manifestation. In this context, criteria for several weather-related risks identification were quantified, the main ones being material damages, the number of casualties and victims and not the least - and the period they occur. The identified weather and climate related risks may be subject to a complex spatiotemporal analysis, having as a research tool - Geographic Information Systems.
Studies on the Implementation of GIS Model in Water Supply Systems
Authors: Lateş Iustina , Luca Mihail , Ilie Gelu , Iurist Nicoleta
Published: December 2016

The paper presents research conducted on the optimization of urban water supply networks. One direction of optimization follows the use of GIS models for digitization on components system. The use of water supply system operation depends on the proper functioning of the structural and functional components.

In the analysis it was found that the main components of the system are the following: capture, headrace, puming stations, reservoirs, distribution networks.

Each component is made up of a multitude of sub-components with specific structural and functional character. Using GIS program it follows to specify custom properties using layers of structural and functional domains. Autocad Civil 3D, GisNet Set, ArcGis Server and Autocad Toolbase programs allowed to obtain thematic maps on specific areas of the system. The model of the study can vary from simple to complex and can be generalized to any water supply system for a specific use (urban area, villages, tourist resorts, shopping complexes etc.).
Wooden Species in the Urban Green Areas and their Role in Improving the Quality of the Environment
Authors: Stratu Anişoara , Costică Naela , Costică Mihai
Published: December 2016

The purpose of this paper is to underline the role of some wooden species in different units of green areas in Iasi municipality in improving the quality of the environment. By regular visits in the field, we have identified the wooden species frequent in different areas; based on the bibliography in the field, we underlined the ecological characteristics, the resistance to unfavourable climate factors, and the role of these species in improving the quality of the environment. Most species taken into account are resistant to extremely cold weather and to drought; are considered resistant (Acer negundo, Acer pseudoplatanus, Hibiscus syriacus, Ligustrum vulgare) or present moderate resistance (Aesculus hippocastanum, Acer platanoides, Philadelphus coronarius) to polluting elements in the atmosphere. The wooden species considered in this study have profound influence on the environment: they regulate the urban microclimate; they contribute to the concentration reduction of some atmospheric pollutants, the noise level; they improve the edaphical conditions and contribute to the soil consolidation. Some species can be used as bio-monitors of the pollution in urban areas.
Infiltration Losses Calculated for the Flash Flood in the Upper Catchment of Geru River, Galaţi County, Romania
Authors: Balan Isabela , Crenganiş Loredana , Corduneanu Flaviana , Pricop Claudiu , Popoiu Loredana Andreea
Published: December 2016

MIKE software created by Danish Institute of Hydraulics can be used to perform mathematical modelling of rainfall-runoff process on the hillslopes, resulting in a runoff hydrograph in the closing section of a catchment. The software includes a unitary hydrograph method - UHM in the hydrological module Rainfall - Runoff. Excess rainfall is routed to the river and transited through unit hydrograph method. The model divides the flood generating precipitation in excess rainfall (net rainfall) and losses (infiltration).

This paper analyzes data from the flash flood that occurred between the 11th and 13th of September 2013 in the upper catchment of the river Geru. The catchment chosen for study, is controlled by the hydrometric station located in the village Cudalbi. Simulations of this flash flood were performed with MIKE by DHI –UHM software, alternatively using as input data the precipitations recorded by AHSS (Automated Hydrological Sensor Station) Cudalbi and radar precipitations generated by ROFFG (Romanian Flash Flood Guidance) software system in ArcGIS module for determining the areas affected by flash floods. The Unitary Hydrograph Method - UHM from the hydrological module Rainfall – Runoff calculates excess rainfall and determines infiltration losses by four methods. For each set of input data, the four methods for calculating infiltration losses were subsequently used.

The comparison between the results highlights that the amplitude and phase errors for the maximum discharge are smaller when the model uses for simulation radar precipitations as input data, and calculates infiltration losses with the Proportional Loss method. This method reproduces with a better accuracy the peaks of the discharge hydrograph. The model can be used in the future to forecast a discharge hydrograph based on estimated radar precipitations in the catchment
Condyloma Latum on the Lower Lip as an Isolated Manifestation of Secondary Syphilis – a Case Report
Authors: Bjekić Milan , Ivanovski Kiro
Published: December 2016

Oral lesions are described in all stages of syphilis, except in the latent stage. During the secondary stage of infection, oral lesions, saliva and blood of infected person are very contagious. The aim of this case report was to point to the secondary syphilis in differential diagnosis of oral diseases.

A 30-year-old homosexual man presented with a three-week history of a painless verrucous lesion on his lower lip. Physical examination revealed a hypertrophic painless papillomatous lesion on the lower lip. The lesion was partly split with peripheral fissures. There were no generalized lymphadenopathies and no evidence of systemic disease. Further examination showed no other mucous membrane or cutaneous lesions elsewhere on the body. The external genitalia were normal. The patient was HIV-negative and otherwise healthy. A review of his medical history was significant for previous well documented treatment of anal chancre, which was successfully commenced at our Institute in 2010. It also revealed a history of a single unprotected receptive oral sex with an unknown partner 3 months before the onset of lesion. The diagnosis of condyloma latum on the lower lip was considered on clinical grounds. Laboratory findings, including complete blood count and blood chemistry were within normal limits. The VDRL (venereal disease research laboratory) test was positive with a titre of 1 : 128. Treponema pallidum hemagglutination assay (TPHA) was positive. HIV serology was non-reactive.

The final diagnosis of solitary condyloma latum on the lower lip, as the only sign of secondary syphilis, was confirmed by positive results of routine serologic tests for syphilis. The patient was diagnosed with secondary syphilis and treated with a single intramuscular injection of benzathine penicillin, 2.4 million units. The lesion regressed completely within 2 weeks. Three months later the VDRL titer had fallen to 1 : 8 and HIV serology remained negative.

Polymorphic oral manifestations in syphilis indicate that this disease should not be overlooked in the differential diagnosis of not only benign, but even malignant oral lesions.

In conclusion, as far as the world literature available to us is concerned, this would be the first report of isolated solitary condyloma latum on the oral lip that, in the absence of any other clinical signs or symptoms of the disease, led to the diagnosis of secondary syphilis.
Changes in Properties of Auditory Nerve Synapses following Conductive Hearing Loss
Authors: Zhuang Xiaowen , Sun Wei , Xu-Friedman Matthew A.
Published: December 2016

Auditory activity plays an important role in the development of the auditory system. Decreased activity can result from conductive hearing loss (CHL) associated with otitis media, which may lead to long-term perceptual deficits. The effects of CHL have been mainly studied at later stages of the auditory pathway, but early stages remain less examined. However, changes in early stages could be important because they would affect how information about sounds is conveyed to higher-order areas for further processing and localization. We examined the effects of CHL at auditory nerve synapses onto bushy cells in the mouse anteroventral cochlear nucleus following occlusion of the ear canal. These synapses, called endbulbs of Held, normally show strong depression in voltage-clamp recordings in brain slices. After 1 week of CHL, endbulbs showed even greater depression, reflecting higher release probability. We observed no differences in quantal size between control and occluded mice. We confirmed these observations using mean-variance analysis and the integration method, which also revealed that the number of release sites decreased after occlusion. Consistent with this, synaptic puncta immunopositive for VGLUT1 decreased in area after occlusion. The level of depression and number of release sites both showed recovery after returning to normal conditions. Finally, bushy cells fired fewer action potentials in response to evoked synaptic activity after occlusion, likely because of increased depression and decreased input resistance. These effects appear to reflect a homeostatic, adaptive response of auditory nerve synapses to reduced activity. These effects may have important implications for perceptual changes following CHL.

SIGNIFICANCE STATEMENTNormal hearing is important to everyday life, but abnormal auditory experience during development can lead to processing disorders. For example, otitis media reduces sound to the ear, which can cause long-lasting deficits in language skills and verbal production, but the location of the problem is unknown. Here, we show that occluding the ear causes synapses at the very first stage of the auditory pathway to modify their properties, by decreasing in size and increasing the likelihood of releasing neurotransmitter. This causes synapses to deplete faster, which reduces fidelity at central targets of the auditory nerve, which could affect perception. Temporary hearing loss could cause similar changes at later stages of the auditory pathway, which could contribute to disorders in behavior.
An atlas of human kinase regulation
Authors: Ochoa David , Jonikas Mindaugas , Lawrence Robert T , El Debs Bachir , Selkrig Joel , Typas Athanasios , Villén Judit , Santos Silvia DM , Beltrao Pedro
Published: December 2016

The coordinated regulation of protein kinases is a rapid mechanism that integrates diverse cues and swiftly determines appropriate cellular responses. However, our understanding of cellular decision‐making has been limited by the small number of simultaneously monitored phospho‐regulatory events. Here, we have estimated changes in activity in 215 human kinases in 399 conditions derived from a large compilation of phosphopeptide quantifications. This atlas identifies commonly regulated kinases as those that are central in the signaling network and defines the logic relationships between kinase pairs. Co‐regulation along the conditions predicts kinase–complex and kinase–substrate associations. Additionally, the kinase regulation profile acts as a molecular fingerprint to identify related and opposing signaling states. Using this atlas, we identified essential mediators of stem cell differentiation, modulators of Salmonella infection, and new targets of AKT1. This provides a global view of human phosphorylation‐based signaling and the necessary context to better understand kinase‐driven decision‐making.
INF-γ encoding plasmid administration triggers bone loss and disrupts bone marrow microenvironment
Authors: Agas Dimitrios , Gusmão Silva Guilherme , Laus Fulvio , Marchegiani Andrea , Capitani Melania , Vullo Cecilia , Catone Giuseppe , Lacava Giovanna , Concetti Antonio , Marchetti Luigi , Sabbieti Maria Giovanna
Published: December 2016

IFN-γ is a pleotropic cytokine produced in the bone microenvironment. Although IFN-γ is known to play a critical role on bone remodeling, its function is not fully elucidated. Consistently, outcomes on the effects of IFN-γ recombinant protein on bone loss are contradictory among reports. In our work we explored, for the first time, the role of IFN-γ encoding plasmid (pIFN-γ) in a mouse model of osteopenia induced by ovariectomy and in the sham-operated counterpart to estimate its effects in skeletal homeostasis. Ovariectomy produced a dramatic decrease of bone mineral density (BMD). pINF-γ injected mice showed a pathologic bone and bone marrow phenotype; the disrupted cortical and trabecular bone microarchitecture was accompanied by an increased release of pro-inflammatory cytokine by bone marrow cells. Moreover, mesenchymal stem cells’ (MSCs) commitment to osteoblast was found impaired, as evidenced by the decline of osterix-positive (Osx+) cells within the mid-diaphyseal area of femurs. For instance, a reduction and redistribution of CXCL12 cells have been found, in accordance with bone marrow morphological alterations. As similar effects were observed both in sham-operated and in ovariectomized mice, our studies proved that an increased IFN-γ synthesis in bone marrow might be sufficient to induce inflammatory and catabolic responses even in the absence of pathologic predisposing substrates. In addition, the obtained data might raise questions about pIFN-γ’s safety when it is used as vaccine adjuvant.
Poesia visual, hipertexto e ciberpoesia
Authors: Caparelli Sérgio , Gruszynski Ana Cláudia , Kmohan Gilberto
Published: December 2016

O recorte deste trabalho limita-se à poesia visual e à poesia hipertextual. Os procedimentos dividiram-se em três fases: foram criados 28 poemas visuais, convergindo técnica e esteticamente o texto escrito com imagens do design, da pintura e outros tipos de desenhos. Foram escolhidos oito desses poemas visuais para serem retrabalhados hipertextualmente por diferentes profissionais. Realizou-se uma parceria com a W3haus para o desenvolvimento de um site e o planejamento de mais alguns ciberpoemas.
Hipertextos, jogos de computador e comunicação
Authors: De Albuquerque Afonso , Pereira de Sá Simone
Published: December 2016

Este artigo trata da transformação do computador em um meio de comunicação. Dizer que o computador é um meio de comunicação parece algo óbvio na era da internet. Mas de que meio de comunicação se trata? Para alguns se trata de um multimídia, capaz de integrar os formatos e linguagens de todos os demais meios. Para outros se trata de algo mais do que isso: ao integrar as linguagem dos outros meios, o computador impõe a elas a sua própria lógica. Mas… qual lógica?
A bússola do escrever: sobre a função da orientação de teses e dissertações
Authors: Neto Machado Ana Maria
Published: December 2016

No presente artigo se trata de chamar a atenção para a importância da função de orientação na produção de conhecimentos e na formação dos pesquisadores, apontando para a lacuna existente nos estudos sobre esta temática. A orientação de teses e dissertações é realizada, na maioria dos casos, por doutores que passaram por atividades de pesquisa pelo menos durante seu mestrado e doutorado. Entretanto, ter recebido orientação e propor-se a praticá-la, por si só não garante o domínio dos processos, procedimentos e estratégias que podem levar a bom termo uma tese ou dissertação. Boa parte deste trabalho implica ler e escrever, dar forma escrita às idéias, experiências e leituras realizadas, atividade para a qual ainda não contamos com uma formação eficaz específica. Colocar em circulação e debate os sucessos e fracassos dos orientadores é urgente e fundamental para qualificar a academia.
Mulheres e moda: a feminilidade comunicada através das roupas
Authors: Neves Strey Marlene
Published: December 2016

Discute-se nesse trabalho como as roupas expressam o self corporal das mulheres, através de pistas culturais e historicas de como a feminilidade pode ser entendida. A moda pode servir como aliada das mulheres na sua busca de espaço no meio da cultura, no mundo do trabalho e para reconhecimento como ser humano. No entanto, a moda pode, também, constituir-se em obstáculo à expressão igualitária, limitando as possibilidades de agilidade física e/ou integração no meio social. O vestir, então, deve ser entendido não como forma de proteção do corpo, mas como veículo ideológico tanto da atração sexual, quanto da construção da feminilidade historicamente determinada.
De Heidegger a Baudrillard: os paradoxos da técnica
Authors: Machado da Silva Juremir
Published: December 2016

Este estudo examina a técnica como vontade de poder ou vontade de potência, numa genealogia que vai de Nietzsche a Baudrillard, debruçando-se, em especial, sobre a questão da técnica em Heidegger.
Desafiando utopias
Authors: Porto Simões Roberto
Published: December 2016

Este artigo refere-se a uma conferência apresentada na cidade de Buenos Aires, Argentina, no Encuentro Interamericano de Estudiantes, Docentes y Profesionales de Relaciones Públicas, organizado pelo Consejo Profesional de Relaciones Públicas de Argentina, no período de 27 a 29 de setembro de 2000. Nele se discute a utopia da atividade de Relações Públicas e também a propria atividade como uma utopia. Faz-se um levantamento de várias autores que trataram do tema e, parafraseando Thomas Morus, coloca-se a atividade de Relações Públicas em uma “ilha”, não no futuro, mas agora, no presente.
A lógica da conversação na conversação sobre a lógica
Authors: Campos Jorge
Published: December 2016

O presente trabalho apresenta considerações sobre as contradições de sentidos que se obtém entre os níveis semântico e pragmático, a partir de um texto de Lewis Carroll. Segundo o autor, tais constatações são importantes para o entendimento das relações entre a racionalidade ao nível das regras lógicas e a racionalidade enquanto ato comunicativo.
Tendencias en la circulación de programas televisivos en el Mercosur
Authors: Mazziotti Nora , Borda Libertad , Heidenhain Carolina , Laura Weiss Maria
Published: December 2016

Este trabalho trata da análise da veiculação dos programas de TV produzidos pelos países membros do Mercosul. O objetivo é apresentar o mapa dos sistemas televisivos dos países que fazem parte do Bloco. Entre estes, há aqueles com produção de programação (Brasil e Argentina) e outros que importam na (Uruguai e Paraguai).
La difusión de Internet: perfil sociológico del adoptante español
Authors: De Miguel Pascual Roberto
Published: December 2016

O objetivo do persente trabalho é diferenciar os perfis dos usuários da Internet na Espanha. A metodologia proposta por Everett M. Rogers per mi te distinguir cinco categorias de usuários diante do processo de aceitação de uma inovação tecnológica. A aplicação empírica realiza-se sobre uma amostra de âmbito nacional de atuais e potenciais usuários de Internet na Espanha. Para diferenciar o comportamento dos indivíduos que representam cada categoria utilizou se a técnica de aná li se de segmentação.
Pensar a internet
Authors: Wolton Dominique
Published: December 2016

Este artigo faz uma refl exão crítica sobre a internet. Para o autor é preciso pensar a internet conforme as dimensões da técnica, da cultura e da sociedade e ainda discutir os três níveis que a revolução da internet se fetua: o internauta, o indivíduo e o cidadão.
Reconfigurações do público e do privado: mutações da sociedade tecnológica contemporânea
Authors: Cristina F. Ferraz Maria
Published: December 2016

Este texto investiga a alteração da dialética público/privado, que marcara a modernidade, no cenário da sociedade tecnológica contemporânea. A partir das teses de Richard Sennett, postas em diálogo com a analítica do poder foucaultiana, a modernidade é caracterizada segundo dois eixos centrais: privilégio do espaço privado sobre a esfera pública, propriamente política, e consolidação de certa experiência de si como interioridade. Nesta virada de século, delineiam-se o declínio de tal experiência de si e a correlata dissolução da nítida fronteira anteriormente traçada entre as esferas do público e do privado, tanto sob a forma da crescente privatização do espaço público quanto da emergência de novas formas de autotematização, de sociabilidade e de percepção de mundo. Como objeto de investigação, privilegia-se uma recente exposição de projetos arquitetônicos de moradias, no MOMA de Nova York, intitulada “A casa nãoprivada”.
A ética como fator de resistência no jornalismo
Authors: Ribeiro Jorge Cláudio
Published: December 2016

O artigo faz uma reflexão sobre a ética e a identidade no interior do jornalimso atual em relação ao avanço das instituições que devem servir a democracia.
A subordinação do jornalismo à lógica capitalista da indústria cultural
Authors: Silveira Fonseca Virginia Pradelina da
Published: December 2016

O presente trabalho visa refletir sobre a implantação da indústria cultural no Brasil, particularmente no ramo da imprensa, e sobre as implicações da introdução da lógica empresarial no jornalismo. Tais reflexões são desenvolvidas a partir de pesquisa bibliográfica sobre o assunto, circunscrita, em linhas gerais, à perspectiva teórica da economia política das comunicações. Para a consecução desses objetivos, iniciaremos fazendo um resgate histórico e do contexto econômico e político de implantação da indústria cultural no Brasil. Num segundo momento, trataremos da perspectiva teórica que orienta nossa leitura do assunto – a economia política -, procurando esclarecer seus pressupostos fundamentais. Por fim, procuraremos tratar com mais especificidade das implicações da introdução da lógica da indústria cultural no jornalismo.