bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Transportation Accessibility on Traffic Volumes in South Korea: An Extreme Gradient Boosting Approach
Authors: Lee Sangwan , Yang Jicheol , Cho Kuk , Cho Dooyong
Published: August 2023

This study explored how transportation accessibility and traffic volumes for automobiles, buses, and trucks are related. This study employed machine learning techniques, specifically the extreme gradient boosting decision tree model (XGB) and Shapley Values (SHAP), with national data sources in South Korea collected from the Korea Transport Institute, Statistics Korea, and National Spatial Data Infrastructure Portal. Several key findings of feature importance and plots in non-linear relationships are as follows: First, accessibility indicators exhibited around 5 to 10% of feature importance except for Mart (around 50%). Second, better accessibility to public transportation infrastructures, such as bus stops and transit stations, was associated with higher annual average daily traffic (AADT), particularly in metropolitan areas including Seoul and Busan. Third, access to large-scale markets may have unintended effects on traffic volumes for both vehicles and automobiles. Fourth, it was shown that lower rates of AADT were associated with higher accessibility to elementary schools for all three modes of transportation. This study contributes to (1) understanding complex relationships between the variables, (2) emphasizing the role of transportation accessibility in transportation plans and policies, and (3) offering relevant policy implications.
Predictors of SARS-CoV-2 Infection and Severe and Lethal COVID-19 after Three Years of Follow-Up: A Population-Wide Study
Authors: Flacco Maria Elena , Acuti Martellucci Cecilia , Soldato Graziella , Di Martino Giuseppe , Rosso Annalisa , Carota Roberto , De Benedictis Marco , Di Marco Graziano , Di Luzio Rossano , Ricci Matteo , Caponetti Antonio , Gori Davide , Manzoli Lamberto
Published: August 2023

In this cohort study, the general population of an Italian Province was followed for three years after the start of the pandemic, in order to identify the predictors of SARS-CoV-2 infection and severe or lethal COVID-19. All the National Healthcare System information on biographical records, vaccinations, SARS-CoV-2 swabs, COVID-19 cases, hospitalizations and co-pay exemptions were extracted from 25 February 2020 to 15 February 2023. Cox proportional hazard analysis was used to compute the relative hazards of infection and severe or lethal COVID-19, adjusting for age, gender, vaccine status, hypertension, diabetes, major cardiovascular diseases (CVD), chronic obstructive pulmonary disease (COPD), kidney disease or cancer. Among the 300,079 residents or domiciled citizens, 41.5% had ≥1 positive swabs during the follow-up (which lasted a mean of 932 days). A total of 3.67% of the infected individuals experienced severe COVID-19 (n = 4574) and 1.76% died (n = 2190). Females, the elderly and subjects with diabetes, CVD, COPD, kidney disease and cancer showed a significantly higher risk of SARS-CoV-2 infection. The likelihood of severe or lethal COVID-19 was >90% lower among the youngest, and all comorbidities were independently associated with a higher risk (ranging from +28% to +214%) of both outcomes. Two years after the start of the immunization campaign, the individuals who received ≥2 doses of COVID-19 vaccines still showed a significantly lower likelihood of severe or lethal disease, with the lowest risk observed among subjects who received at least one booster dose.
Phage-Defense Systems Are Unlikely to Cause Cell Suicide
Authors: Fernández-García Laura , Wood Thomas K.
Published: August 2023

As new phage-defense systems (PDs) are discovered, the overlap between their mechanisms and those of toxin/antitoxin systems (TAs) is becoming clear in that both use similar means to reduce cellular metabolism; for example, both systems have members that deplete energetic compounds (e.g., NAD+, ATP) and deplete nucleic acids, and both have members that inflict membrane damage. Moreover, both TAs and PDs are similar in that rather than altruistically killing the host to limit phage propagation (commonly known as abortive infection), both reduce host metabolism since phages propagate less in slow-growing cells, and slow growth facilitates the interaction of multiple phage-defense systems.
Genomic Surveillance of Rabies Virus in Georgian Canines
Authors: Huaman Celeste , Paskey Adrian C. , Clouse Caitlyn , Feasley Austin , Rader Madeline , Rice Gregory K. , Luquette Andrea E. , Fitzpatrick Maren C. , Drumm Hannah M. , Yan Lianying , Cer Regina Z. , Donduashvili Marina , Buchukuri Tamar , Nanava Anna , Hulseberg Christine E. , Washington Michael A. , Laing Eric D. , Malagon Francisco , Broder Christopher C. , Bishop-Lilly Kimberly A. , Schaefer Brian C.
Published: August 2023

Rabies is a fatal zoonosis that is considered a re-emerging infectious disease. Although rabies remains endemic in canines throughout much of the world, vaccination programs have essentially eliminated dog rabies in the Americas and much of Europe. However, despite the goal of eliminating dog rabies in the European Union by 2020, sporadic cases of dog rabies still occur in Eastern Europe, including Georgia. To assess the genetic diversity of the strains recently circulating in Georgia, we sequenced seventy-eight RABV-positive samples from the brain tissues of rabid dogs and jackals using Illumina short-read sequencing of total RNA shotgun libraries. Seventy-seven RABV genomes were successfully assembled and annotated, with seventy-four of them reaching the coding-complete status. Phylogenetic analyses of the nucleoprotein (N) and attachment glycoprotein (G) genes placed all the assembled genomes into the Cosmopolitan clade, consistent with the Georgian origin of the samples. An amino acid alignment of the G glycoprotein ectodomain identified twelve different sequences for this domain among the samples. Only one of the ectodomain groups contained a residue change in an antigenic site, an R264H change in the G5 antigenic site. Three isolates were cultured, and these were found to be efficiently neutralized by the human monoclonal antibody A6. Overall, our data show that recently circulating RABV isolates from Georgian canines are predominantly closely related phylogroup I viruses of the Cosmopolitan clade. Current human rabies vaccines should offer protection against infection by Georgian canine RABVs. The genomes have been deposited in GenBank (accessions: OQ603609-OQ603685).
Deep Sequencing to Reveal Phylo-Geographic Relationships of Juquitiba Virus in Paraguay
Authors: Nnamani Evans Ifebuche , Spruill-Harrell Briana , Williams Evan Peter , Taylor Mariah K. , Owen Robert D. , Jonsson Colleen B.
Published: August 2023

Several hantaviruses result in zoonotic infections of significant public health concern, causing hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS) in the Old and New World, respectively. Given a 35% case fatality rate, disease-causing New World hantaviruses require a greater understanding of their biology, genetic diversity, and geographical distribution. Juquitiba hantaviruses have been identified in Oligoryzomys nigripes in Brazil, Paraguay, and Uruguay. Brazil has reported the most HCPS cases associated with this virus. We used a multiplexed, amplicon-based PCR strategy to screen and deep-sequence the virus harbored within lung tissues collected from Oligoryzomys species during rodent field collections in southern (Itapúa) and western (Boquerón) Paraguay. No Juquitiba-like hantaviruses were identified in Boquerón. Herein, we report the full-length S and M segments of the Juquitiba hantaviruses identified in Paraguay from O. nigripes. We also report the phylogenetic relationships of the Juquitiba hantaviruses in rodents collected from Itapúa with those previously collected in Canindeyú. We showed, using the TN93 nucleotide substitution model, the coalescent (constant-size) population tree model, and Bayesian inference implemented in the Bayesian evolutionary analysis by sampling trees (BEAST) framework, that the Juquitiba virus lineage in Itapúa is distinct from that in Canindeyú. Our spatiotemporal analysis showed significantly different time to the most recent ancestor (TMRA) estimates between the M and S segments, but a common geographic origin. Our estimates suggest the additional geographic diversity of the Juquitiba virus within the Interior Atlantic Forest and highlight the need for more extensive sampling across this biome.
Innate Immune Response to Viral Vectors in Gene Therapy
Authors: Wang Yixuan , Shao Wenwei
Published: August 2023

Viral vectors play a pivotal role in the field of gene therapy, with several related drugs having already gained clinical approval from the EMA and FDA. However, numerous viral gene therapy vectors are currently undergoing pre-clinical research or participating in clinical trials. Despite advancements, the innate response remains a significant barrier impeding the clinical development of viral gene therapy. The innate immune response to viral gene therapy vectors and transgenes is still an important reason hindering its clinical development. Extensive studies have demonstrated that different DNA and RNA sensors can detect adenoviruses, adeno-associated viruses, and lentiviruses, thereby activating various innate immune pathways such as Toll-like receptor (TLR), cyclic GMP-AMP synthase–stimulator of interferon genes (cGAS-STING), and retinoic acid-inducible gene I–mitochondrial antiviral signaling protein (RLR-MAVS). This review focuses on elucidating the mechanisms underlying the innate immune response induced by three widely utilized viral vectors: adenovirus, adeno-associated virus, and lentivirus, as well as the strategies employed to circumvent innate immunity.
Effects of Severe Acute Respiratory Syndrome Coronavirus Vaccination on Reinfection: A Community-Based Retrospective Cohort Study
Authors: Gim Hyerin , Lee Seul , Seo Haesook , Park Yumi , Chun Byung Chul
Published: August 2023

Background: Coronavirus disease 2019 (COVID-19) is a disease that is characterized by frequent reinfection. However, the factors influencing reinfection remain poorly elucidated, particularly regarding the effect of COVID-19 vaccination on preventing reinfection and its effects on symptomatology and the interval until reinfection. Methods: This retrospective cohort study examined patients with severe acute respiratory syndrome coronavirus reinfection between January 2020 and February 2022. This study included patients aged >17 years who were reinfected at least 90 days between two infections with severe acute respiratory syndrome coronavirus. The main outcome measure was a reduction in symptoms during reinfection, and reinfection interval. Results: Overall, 712 patients (average age: 40.52 ± 16.41 years; 312 males) were included. The reduction rate of symptoms at reinfection than that at first infection was significantly higher in the vaccinated group than in the unvaccinated group (p < 0.001). The average reinfection interval was 265.81 days. The interval between the first and second infection was 63.47 days longer in the vaccinated group than in the unvaccinated group. The interval was also 57.23 days, significantly longer in the asymptomatic group than in the symptomatic group (p < 0.001). Conclusions: Besides its role in preventing severe acute respiratory syndrome coronavirus infection, vaccination reduces the rate of symptomatic reinfection and increases the reinfection interval; thus, it is necessary to be vaccinated even after a previous infection. The findings may inform the decision to avail COVID-19 vaccination.
Efficacy and Safety of Vaccinations in Geriatric Patients: A Literature Review
Authors: Ciarambino Tiziana , Crispino Pietro , Buono Pietro , Giordano Vincenzo , Trama Ugo , Iodice Vincenzo , Leoncini Laura , Giordano Mauro
Published: August 2023

With the progressive lengthening of the average age of the population, especially in some countries such as Italy, vaccination of the elderly is a fixed point on which most of the public health efforts are concentrating as epidemic infectious diseases, especially those of the winter, have a major impact on the progression of severe disease, hospitalization, and death. The protection of the elderly against acute infectious diseases should not only limit mortality but also have a positive impact on the fragility of these people in terms of less disability and fewer care needs. However, vaccination of the elderly population differs in efficacy and safety compared to that of other population categories since aging and the consequent loss of efficiency of the immune system lead to a reduction in the immunogenicity of vaccines without achieving a lasting antibody coverage. There are various strategies to avoid the failure of immunization by vaccines such as resorting to supplementary doses with adjuvant vaccines, increasing the dosage of the antigen used, or choosing to inoculate the serum relying on various routes of administration of the vaccine. Vaccination in the elderly is also an important factor in light of growing antibiotic resistance because it can indirectly contribute to combating antibiotic resistance, reducing theoretically the use of those agents. Furthermore, vaccination in old age reduces mortality from infectious diseases preventable with vaccines and reduces the same rate of resistance to antibiotics. Given the importance and complexity of the topic, in this review, we will deal with the main aspects of vaccination in the elderly and how it can influence mortality and healthcare costs, especially in those countries where population aging is more evident. Therefore, we conducted a systematic literature search in PubMed to identify all types of studies published up to 31 May 2023 that examined the association between vaccination and the elderly. Data extraction and quality assessment were conducted by two reviewers (PC and TC) who independently extracted the following data and assessed the quality of each study.
Nurturing a Respectful Connection: Exploring the Relationship between University Educators and Students in a Spanish Veterinary Faculty
Authors: Ramírez Ana S. , Jaber José Raduan , Rosales Rubén S. , Conde-Felipe Magnolia , Rodríguez Francisco , Corbera Juan Alberto , Suárez-Pérez Alejandro , Encinoso Mario , Muniesa Ana
Published: August 2023

The respect of the teacher for the student is essential for effective teaching from the perspective of the students, even in comparison to the knowledge and communication capacity of the teacher. Consequently, the optimal development of this characteristic fosters a more effective and efficient student–teacher relationship. We initiated this research following a conversation with a group of university students, who expressed their discontent regarding the lack of respect shown towards them by some teachers. Therefore, we conducted a descriptive study using online surveys, focusing on the central axis in the teacher–student relationship. The results highlighted the need for faculty members to analyze and question their attitudes towards their students. This paper presents initial results of the data collected at the Veterinary Faculty of the University of Las Palmas de Gran Canaria.
SPH Simulation of Sediment Movement from Dam Breaks
Authors: Zheng Xiaogang , Rubinato Matteo , Liu Xingnian , Ding Yufei , Chen Ridong , Kazemi Ehsan
Published: August 2023

This study aims to develop a robust sediment transport model focusing on the vertical two-dimensional water–sediment two-phase flow in which sediments are constantly interacting, hitting each other, gradually becoming smoother and smaller, and accumulating when velocities decrease. The grid-based models currently available can be cumbersome when dealing with phenomena that require replication of this water–sediment interface. Therefore, a two-dimensional water–sediment two-phase flow model based on Smoothed Particle Hydrodynamics (SPH) is established in the macroscopic scale to simulate a large amount of sediment accumulation and propagation typical of a landslide caused by a dam break. In this study, water and sediments are treated as two kinds of fluids with different densities and viscosities to accurately simulate the flow structure, the sediment transport, and the water–sediment interaction process. The interaction model developed treats the interface of the two phases within a unified framework. The model developed was then tested against three applications, and the results obtained confirmed its accuracy in correctly replicating the movement of the sediment phase. The preliminary results obtained can be helpful in providing further insights into the mixing of water and sediments and their propagation following a dam break and the consequent wave profile generated.
Comprehensive Evaluation and Distribution Prediction of River Water Quality in One Typical Resource-Depleted City, Central China
Authors: Huai Zhiwen , Ma Jianmin , Wang Shishi , Qi Shang , Xu Tao , Riaz Luqman , Huang Yongwen , Bai Xiongxiong , Wang Jihua , Lin Qingwei
Published: August 2023

Access to clean and equitable water is vital to human survival and an essential component of a sustainable society. Using 59 monitoring sections, the water quality of 32 rivers in 12 river systems within two river basins in one resource-depleted city (Jiaozuo) was examined in four seasons to better comprehend the extent of river pollution, and the distribution prediction of main indexes was conducted. In total, 92% of the monitoring sections met the national standards. Overall, 12.5%, 62.5%, and 25% of samples met water quality standards III, IV, and V, respectively. The concentrations of total nitrogen (TN), total phosphorus (TP), and chemical oxygen demand (COD) ranged from 0.527 to 7.078, 0.001 to 1.789, and 0.53 to 799.25 mg/L, respectively. The Yellow River Basin has higher annual mean concentrations of total carbon (TC), TN, and total organic carbon (TOC) than the Haihe River Basin. The highest and lowest concentrations of specific water quality indices varied across seasons and rivers. Dashilao and Rongyou Rivers have the best water quality, while Dasha, Xin, and Mang Rivers have the worst. TN, TP, and NH4+-N concentrations in the Laomang River midstream were greater than those upstream and downstream. Statistically, significant positive associations were found between NH4+-N and TC, TOC, and COD (p < 0.025), where NH4+-N and COD influenced water quality the most. A significant positive relationship between COD and TP (p < 0.01) was observed. Overall, water quality values were highest in the summer and lowest in winter. The distribution prediction revealed TN, TP, NH4+-N, and COD showed significant regional differences. Household sewage, industrial sewage discharge, and agricultural contamination were all the possible significant contributors to declining water quality. These findings could provide a scientific reference for river water resource management in resource-depleted cities.
Estimating Natural Boundary Change on a Large Lake
Authors: Hiles Clayton E. , Morris Eric , Sutherland Craig , Bazett Dave , Davey Chad
Published: August 2023

The natural boundary is intuitively understood to be the line dividing the bed of a water body from the adjacent land. It is used in many jurisdictions to define the boundary of ownership between a land parcel and a state-owned watercourse. It is typically defined on the ground through observations by a professional surveyor. Predicting changes to the natural boundary has obvious utility (e.g., with climate change); however, its’ observational nature does not lend itself to such predictions. This paper uses a case study of a large lake to explore the relationship between shoreline morphology and hydrology, and the elevation of the natural boundary. Significant correlation was found between the natural boundary elevation and average wave power, but not with variables beach slope, sediment type, or presence of vegetation. Below 0.4 W/m of average wave power, the correlation with natural boundary elevation is very weak, suggesting a lower limit of influence. Two process-based methods for estimation of natural boundary change are proposed, one based on the observed statistical relationship between the average wave power and the natural boundary elevation, and another method based on detailed analytical modelling of bottom stress from breaking waves using the Xbeach software (v1.23). Both methods were used to estimate natural boundary change under a hypothetical change in water level regime due to proposed weir upgrades. While observational data are not available to support evaluation, both approaches predict similar changes to the natural boundary despite their significantly different basis. While the modelling approach requires significant analyst and computational effort, the parametric approach is comparatively efficient, making it practical to apply at high resolution over very large shorelines.
Estimating Typhoon-Induced Maximum Flood for Spillway Safety Assessment—Case Studies in Taiwan
Authors: Lee Kwan Tun , Hsu Yu-Han , Yang Jing Zong
Published: August 2023

Dam safety assessment is usually conducted regularly to investigate the risks associated with the dam and propose remedies to ensure effective reservoir operations. One crucial aspect of the evaluation involves performing hydrological analyses to determine if the existing spillway can successfully deliver the probable maximum flood (PMF) downstream. This study applied storm transposition and typhoon rainstorm methods for PMP estimations. The resulting PMP values were then used as input for runoff models to generate flood hydrographs for PMF determination. A modification for the storm transposition method was proposed to determine the barrier height considering the moisture inflow direction. In estimating the orographic rainfall in the typhoon rainstorm model, an effective terrain slope was suggested according to different windward directions based on DEM analysis. Shihmen Reservoir and Feitsui Reservoir, located in northern Taiwan, were used as examples to conduct the PMP and PMF analysis. The obtained PMPs were further compared with the results generated by Hershfield’s method to assess the reasonability of the estimation. The results show that the maximum deviation of the 24-h PMP values estimated by the three methods is within 30% in the Shihmen watershed and 16% in the Feitsui watershed. The PMF estimations in the two reservoir watersheds are larger than the design discharges of the existing spillways. Hence, extending the capacity of the existing spillways or constructing upstream bypasses to avoid catastrophic flooding downstream is required.
Study on Lane-Change Replanning and Trajectory Tracking for Intelligent Vehicles Based on Model Predictive Control
Authors: Li Yaohua , Zhai Dengwang , Fan Jikang , Dong Guoqing
Published: August 2023

When an intelligent vehicle changes lanes, the state of other vehicles may change, which increases the risk of collision. Therefore, real-time local path replanning is needed at this time. Based on model predictive control (MPC), a lane-change trajectory replanning strategy was proposed, which was divided into a lane-change trajectory correction strategy, a lane-change switchback strategy and forward active collision avoidance strategy according to collision risk. Based on the collision risk function of the rectangular safety neighborhood, the objective functions were designed according to the specific requirements of different strategies. The vehicle lateral controller based on MPC and the vehicle longitudinal motion controller were established. The longitudinal velocity was taken as the joint point to establish the lateral and longitudinal integrated controller. The trajectory planning module, trajectory replanning module and trajectory tracking module were integrated in layers, and the three trajectory replanning strategies of lane-change trajectory correction, lane-change switchback and forward active collision avoidance were respectively simulated and verified. The simulation results showed the trajectory replanning strategy achieves collision avoidance under different scenarios and ensures the vehicle’s driving stability. The trajectory tracking layer achieves accurate tracking of the conventional lane-change trajectory and has good driving stability and comfort.
Classification of Russian Regions by the Level of Agricultural Development in 2019–2021
Authors: Mkhitaryan V. S. , Popova G. L.
Published: August 2023

The urgency of improving mathematical and statistical tools for analyzing agricultural complex across the territories of our country depends on the gravity of the issue of interregional differentiation of the scale of development of agricultural production, which plays a crucial role in the implementation of the Food Security Doctrine of the Russian Federation.

The introductory part of the article presents an overview of the literature on food security issues, an analysis of the current state of domestic agriculture, and directions for its development. The body of the article explains the research methodology, which allows to classify, first andforemost, agricultural regions (indicating their territorial location, socio-economic characteristics, and predictive characteristics). As an indicator of the intensity of agricultural development in the regions, the authors used the volume of agricultural production per capita, which became a criterion for selecting 25% of the regions with the maximum values of this indicator. That said, by an agro-region (or agricultural region) is meant a region that produces more agricultural production than needed and exports its surplus outside the region or country (food exports). In the multidimensional classification of agro-regions, three clusters are determined (according to the level of socio-economic development, the development efficiency of the economic activity «Agriculture, forestry, hunting, and fishing», and the volume of crop and livestock production). The paper analyses the dynamics and predictive characteristics of the development of the cluster-average volume of agricultural production per capita (including crop production and animal husbandry). An analysis of the dynamics of exports of food products and agricultural raw materials per capita by clusters revealed that the regions of the first cluster are the most actively developing, and the regions of the third cluster (with the most developed animal husbandry) are oriented towards domestic consumers.

According to the authors, during the analyzed period in Russia, there was a positive trend in the development of agriculture, with the development of agro-regions outpacing all-Russian trends. The highest development rates are typical for agro-regions with a balanced development of crop and livestock production (regions of the first cluster).
The Essay in Early Modem and Late Modem English Medical Writing
Authors: Taavistainen Irma
Published: August 2023

Cet article aborde l’essai de langue anglaise et s’inscrit dans la théorie des prototypes. Il décrit la genèse de ce genre, son développement ainsi que les transformations qu’il a subies sur une période de deux siècles, avec un intérêt particulier pour le texte non littéraire et la littérature médicale. Cette étude utilise des méthodologies variées : analyse de l’expression métacommunicationnelle, linguistique de corpus, analyse du discours. Les sources sont tirées des corpus digitalisés EEBO et ECCO et de deux corpus spécialisés dans le discours médical, EMENT et LMENT. Les résultats montrent que le genre s’est étendu à d’autres domaines et s’est grandement développé. L’appellation a fréquemment été appliquée à des documents médicaux hautement spécialisés destinés à un lectorat savant appartenant à un public éduqué.
XIX. Yüzyıla Ait Bir Münacatname ve Tarama Sözlüğü’ne Katkıları
Authors: CİHAN Serkan
Published: August 2023

Arapça nevc kökünden türemiş bir kelime olan münacat, ‘kulağa fısıldama’ anlamındadır. Türk, Arap ve Fars edebiyatlarında ise konusu Allah’a yakarış, yalvarma ve dua olan şiir şeklinde tanımlanır. Türün mensur olarak kaleme alınan örnekleri ise azdır. Elimizdeki yazma, mensur olarak yazılmış ender örneklerden birisidir. Yazma, Konyalı Hasan amcamızın sandığından çıkmış, nesilden nesile saklanarak günümüze kadar ulaşmıştır. 74 varaklı bu münacatnamenin her sayfasında yedi satır bulunmaktadır. Münacatname, bünyesinde birçok Arapça dua ve Türkçe menkıbeleri içermektedir. 19. yüzyılın başlarında yazılan eser, Türk dili tarihi ve söz varlığı için önemli kelimeleri barındırmaktadır. Eser, özellikle Tarama Sözlüğü’nde bulunmayan kelimeleri içermesi bakımından önem arz etmektedir. Oldukça geniş çaplı bir çalışmanın ürünü olarak niteleyebileceğimiz bu sözlük, halihazırda alanda araştırma yapan yerli ve yabancı birçok akademisyenin baş ucu kaynakları arasında yer almaktadır. Buna rağmen sözlüğün, yeni eserlerin ortaya çıkmasıyla birlikte yenilenmeye ihtiyacı olduğu da açıktır. Bu çalışmada, Tarama Sözlüğü’nde bulunmayan ya da farklı anlamlarla bulunan 29 kelime ve kelime grubu incelenmiştir.
Evaluation of Hounsfield Unit Value and Radiomorpometric Indexs in Panoramic Radiographs of Patients with Bruxism
Authors: KOTANLI Sedef , YAVUZ Yasemin , ULUİSİK Nurbanu , DOĞAN Mehmet Emin
Published: August 2023

Background: The aim of this retrospective study is to evaluate the effects of bruxism on the mandibular bone using radiomorphometric indices and Hounsfield unit (HU) value on digital panoramic radiography (DPR).
Materials and Methods: Panoramic radiographs of 120 patients, 60 with bruxer and 60 without (control), were analyzed. Mental index (MI), panoramic mandibular index (PMI), antegonial index (AI), gonial index (GI), antegonial notch depth (AND) and mandibular cortical index (MCI) were measured bilaterally in DPR. Gray values of the cancellous bone and cortical bone at predetermined landmarks in the mandible were measured using the HU value on the DPR.
Results: MI was found to be higher and statistically significant in bruxers compared to the control group (p<0.05). There was no statistically significant difference between the bruxism group and the control group in terms of AI, GI and MCI (p>0.05). While there was a significant difference in HU value in the cancellous bone in the bruxism group and the control group (p<0.05), there was no statistically significant difference in HU values between the two groups in the cortical bone (p>0.05).
Conclusions: MI and AND measurements can be used in the diagnosis or follow-up of bruxism. There is no diffe-rence in mandibular cortical bone height in patients with and without bruxism according to AI, GI, and MCI. The mean PMI value measured on the left side differs between the groups. In bruxism patients, increased density in the mandibular cancellous bone, is greater and significantly different from the increase in cortical bone.
PANDEMI COVID-19 SEBAGAI MOMENTUM KONSOLIDASI WISATA NOMADIK DI KAWASAN CANGGU, BALI
Authors: Bernada Chelsea Chety , Roychansyah M. Sani
Published: August 2023

The Canggu area is one of the most popular nomadic tourist destinations in the world. This makes the development of the Canggu area increasingly important. With the COVID-19 pandemic, the nomadic style of tourism in the Canggu area has become adaptive tourism during the pandemic. This study aims to determine the stages of development of nomadic tourism in the Canggu area using a deductive qualitative method. The results of the study show that the Canggu area has undergone four stages: exploration, involvement, development, and consolidation. Observations show that currently Canggu Area tourism in the tourism area life cycle analysis is at stage 4, or the consolidation stage. COVID-19 has brought this area to a consolidation stage. The existence of the COVID-19 pandemic requires the concept of nomadic tourism to adapt and strengthen its quality. This has received a positive response as seen from a good reputation and structure in accommodating the needs of digital nomads that occurred during the pandemic in this region. so that the consolidation phase can strengthen the attractiveness of the Canggu Area as a nomadic tourism destination in the future.
Estudos de validade e confiabilidade da Escala de Avaliação dos Efeitos da Musicoterapia em Grupo na Dependência Química (MTDQ)
Authors: Pedrosa Frederico , Garcia Frederio , Gomes Cristiano Mauro Assis , Loureiro Cybelle Maria
Published: August 2023

A Escala de Avaliação dos Efeitos da Musicoterapia em Grupo na Dependência Química (MTDQ) é um teste de autorrelato composto por 20 itens que avaliam os benefícios percebidos por pacientes adultos com dependência química sobre os efeitos da musicoterapia em grupo em seus processos de mudança. A MTDQ possui evidências de validade de conteúdo, mas carece de análises sobre outros aspectos da validade de um teste. Este estudo objetivou avaliar a validade estrutural e a confiabilidade da MTDQ. Através da análise fatorial confirmatória de itens, três modelos foram testados: unidimensional, dois fatores correlacionados e bifatorial. A amostra possui 202 adultos (44,7±12,7; 23,37%, mulheres) com dependência química que participaram de grupos de musicoterapia e responderam a MTDQ em um Centro de Referência de Saúde Mental Álcool e Drogas na cidade de Belo Horizonte/MG. Os resultados indicam adequação da estrutura bifatorial, composta por dois fatores específicos (processos cognitivos e processos comportamentais) e um fator geral.  Este estudo traz evidências iniciais de que a MTDQ é um instrumento apropriado para medir três benefícios percebidos pelos pacientes com dependência química sobre a musicoterapia em seus processos de mudança.
Ambientes de aprendizaje en educación inicial: experiencias pedagógicas de atención integral en el municipio de Ibagué
Authors: Duque Romero Claudia Alejandra , Henao Morales Laura Yamile , López López Viviana Alexandra
Published: August 2023

En esta cartilla encontrarán reflexiones sobre la educación inicial en el marco del enfoque de la atención integral para la primera infancia que apuntan a conocer el sentido de las apuestas del Ministerio de Educación, y orientar las transformaciones pedagógicas en esta dirección. Sabemos que el país transita hacia una ampliación de cobertura, por lo cual se convierte en una oportunidad para visibilizar esfuerzos y estrategias pedagógicas, así como para pensar en los retos en cuanto a la prestación de servicios de educación inicial en las instituciones educativas del municipio de Ibagué.
COMPORTAMENTO DO CONSUMIDOR NA COMPRA E CONSUMO DE PRODUTOS DA AGRICULTURA FAMILIAR
Authors: Gollo Silvana Saionara , Dal'Agnol Sidnei , Da Rosa Keila Cristina , Grzybovski Denize
Published: August 2023

A pesquisa tem por objetivo analisar o comportamento de compra e consumo de produtos da agricultura familiar. Especificamente, objetivou-se identificar o perfil dos consumidores, hábitos e motivos que influenciam a decisão de compra e consumo e traçar estratégias de marketing para a agricultura familiar. A pesquisa classifica-se como exploratória/quantitativa e o método é o Levantamento do tipo Survey. Foram pesquisados 311 consumidores que se autodeclararam consumidores de produtos da agricultura familiar. Os dados foram coletados em uma feira de produtos da agricultura familiar, assim como de forma on-line, através da aplicação de questionário estruturado. Os resultados indicam que os consumidores de produtos da agricultura familiar são na maioria jovens, do gênero feminino e masculino, com ensino médio ou superior. A maior parte dos pesquisados identificou-se como pequeno ou médio usuário de produtos da agricultura familiar. Esses consumidores reconhecem os produtos da agricultura familiar como mais naturais, sustentáveis, sem agrotóxicos e produtos que protegem o meio ambiente. A partir dos resultados sobre o perfil, hábitos e motivos de compra e consumo, foi possível propor estratégias de marketing direcionadas à diversificação e embalagens de produtos, divulgação, distribuição e precificação de produtos.
Surface-activated direct bonding of diamond (100) and c-plane sapphire with high transparency for quantum applications
Authors: Miyatake Tetsuya , Kawaguchi Kenichi , Ohtomo Manabu , Iwai Toshiki , Ishiguro Tetsuro , Doi Yoshiyasu , Hermias Jeffrel , Nur Salahuddin , Ishihara Ryoichi , Sato Shintaro
Published: August 2023

Surface-activated direct bonding of diamond (100) and c-plane sapphire substrates is investigated using Ar atom beam irradiation and high-pressure contact at RT. The success probability of bonding strongly depends on the surface properties, i.e, atomic smoothness for the micron-order area and global flatness for the entire substrate. Structural analysis reveals that transformation from sapphire to Al-rich amorphous layer is key to obtaining stable bonding. The beam irradiation time has optimal conditions for sufficiently strong bonding, and strong bonding with a shear strength of more than 14 MPa is successfully realized. Moreover, by evaluating the photoluminescence of nitrogen-vacancy centers in the diamond substrate, the bonding interface is confirmed to have high transparency in the visible wavelength region. These results indicate that the method used in this work is a promising fabrication platform for quantum modules using diamonds.
Profesionalización docente en Educación Parvularia: Análisis de mecanismos discursivos que construyen representaciones de feminidad v/s masculinidad en el perfil de educadoras/es de párvulos
Authors: Martínez Palma Elizabeth , Uribe Pilar
Published: August 2023

Este artículo identifica los mecanismos discursivos que construyen percepciones identitarias profesionales en educadoras/es de párvulos a partir de sus representaciones de género, pues en Chile, desde el S.XX, se ha naturalizado la educación infantil como una extensión de la crianza y del espacio doméstico al contexto profesional (MINEDUC 2017). El trabajo aborda una metodología cualitativa que incorpora el Modelo de Valoración (Martin y White 2005), inscrito en la Lingüística Sistémico Funcional (LSF), para examinar la construcción de significados valorativos expresados por educadoras de párvulos, respecto a la feminización en su identidad profesional. Los resultados destacan que esta identidad está basada en la extensión de la maternidad moral (Valdés et al. 2006) como eje de la comprensión del rol profesional. De igual modo se observa el predominio y liderazgo femenino en el ámbito de la educación infantil, aun cuando se considera necesaria la incorporación masculina en el acto educativo, pero en roles secundarios.
البناء الفني للقصة القرآنية
Authors: جادري الأستاذ المساعد الدكتور   سهاد
Published: August 2023

تناول هذا المقال البناء الفني للقصة القرآنية في البداية تحدثنا عن كلمة القصة لغة ومصطلحات وتحدثنا عن خصائص القصة الناجحة وأنواع القصص العربية ثم قدمنا ​​دراسة تحليلية في القصص القرآن الكريم واختتم بحثنا بالنتائج التي حصلنا عليها من خلال البحث. أما المنهجية المتبعة فقد تمت دراسة تفسير القرآن الكريم والآيات المتعلقة بالقصص القرآنية دراسة تحليلية وفنية.
رموز آلهة المياه في الثقافة الإيرانية
Authors: شهریاری ناهید , تیموري شهرزاد
Published: August 2023

إن البصيرة الدينية للإنسان البدائي، جسدت القوى العليا للأرض والسماء في الأصل الأنثوي للكون والذي أصبح فيما بعد الأساس العظيم للأم الأولية، وكان الناس يدورون حولها ويعبدونها. الأسطورة هي نوع من تفسير الكون الذي يأتي على شكل قصص عن الآلهة والملائكة وأمشاسباندان، وهو القدر المقدس الذي حدث بالفعل والآن في شكل من أشكال الخيال والرمز، يتحدث عن كيفية ظهور الأشياء إلى الوجود أو فناءها. لأن أساطير الإنسان القديم كالكتب المقدسة، تعلمه الأخلاق والوصايا العملية. أناهيتا هي إلهة إيرانية قديمة، كانت موجودة قبل زرادشت وكانت تُعبد. أصبحت زاوية قوية بعد صعود زرادشت وأقيمت لها الاحتفالات والبركات. نقدم هنا وننظر في الرموز المتعلقة بـ أناهيتا في إيران.
مصطلحات "الإرث" في فقه الأديان الخمسة
Authors: حصار نادر
Published: August 2023

"الإرث" هو مالي يتم الوصية به، لذلك، باعتبار أن أحد أهم أجزاء الوصية هو "إرث" الوصية. ولذلك ذهب فقهاء الإسلام أيضاً إلى صحة تلك الشروط وجعلها، تخضع لعدة شروط، ولذلك فإن بعض شروط صحة "الإرث" هي: أ) أن يكون ملكاً، لأن الوصية هي حقوق ملكية وما لا وجود له لا يقبل، ب) أن يكون له ثمن و ج- أن يكون قابلاً للحيازة، وإن لم يكن موجوداً عند رغبة الإنسان، ولذلك يرى الفقهاء صحة الوصية للمنافع، وكذلك الإرادة وغير الشخصية. كالوصية من الحب والثمر ونحو ذلك. د- أن يكون ملكاً للموصي، ولذلك اشترط الفقهاء أنه إذا كان "الإرث" موجوداً، فيجب أن يكون ملكاً "للموصي" عند وقت الوصية، لأن الوصية بالمال غير كاذبة. هـ- أن يكون فيه فائدة عقلية شرعية لأنهم في نظرهم يقصدون تصحيح نعمة الموصي في حياته، ولذلك لا تجوز الوصية بالوصية بالذنب كما ذهب الفقهاء. وجاء في وصية حرمان بعض الورثة أن مثل هذا الفعل محرم: وله قابلية النقل، لأن بعض الحقوق، ومنها حق التقاضي وحق الرجوع ونحو ذلك، لا يمكن الوصية بها. إلا أن الفقهاء اعتبروا شرطين لتنفيذ الوصية في "التركة": الأول: أن لا تشمل ديون الموصي جميع أمواله وتراثه، لأن الدين في هذه الحالة لا ينفذ. الارادة؛ وثانياً: يرى أغلب فقهاء المذاهب أنهم إذا ورثوا ورثة فلا يجوز أن "يزيدوا على ثلث التركة". ومع ذلك، لديهم جدل حول عدم وجود الميراث.
الجماليات البنيوية في سورة «الشمس» المباركة
Authors: تاجيك طالبة الدكتوراه رؤيا , فر الدكتور محمد , غضنفري سيد علي
Published: August 2023

ولا شك أن الغوص في بحر الله تبارك وتعالى يتجلى في ظاهرة تسمى بظاهرة اللغة، والدخول في المجالات اللغوية هو السبيل الوحيد إلى هذا المجال. إن البنية اللغوية للقرآن تساعد في جميع العصور دراسة متعددة الأوجه لكشف العجائب الخفية. إن المنهج البنائي هو أحد الأساليب التي تساعدنا على فهم معاني القرآن وإظهار الإمكانات الموجودة فيه. ومن هذا المنطلق، فإن هذا الجهد المتواضع، القائم على المنهج البنيوي، يحاول دراسة "شمس" الشمس المباركة، وتوسيع علاقة هذا المنهج بمحتوياته الغنية. ومن خلال هذه الدراسة سيتم إظهار بناء هذه السورة على المستويات الصوتية والنحوية والبلاغية واللغوية. وما وصلنا إليه في المقام الأول هو أن هذه السورة نزلت في بناء متضامن وموضوعي متماسك، ليصبح القسم الأول من هذه السورة مقدمة للموضوعات المذكورة في القسمين الثاني والثالث. ثانيًا، يوجد توازن صوتي خاص في سياق الصورة بأكملها. جميع العلامات مختومة بالصوت، والتوازن النحوي واللغوي في استخدام التكرار والقسمة هو ما ساعد مصممي السرة وأهدافهم الرئيسية على التوجه إلى
الفن الرقمي رؤية ذاتية جديدة في أنتاج مخططات تصميمية تجريبية لفن الجداريات برنامج ( Corel Draw ) إنمودجاً
Authors: الحكيم المدرس المساعد  مشتاق , كاظم الأستاذ المساعد الدكتور  أحمد
Published: August 2023

تعتبر الفنون الرقمية والوسائط المتعددة عنصرا فعالا في تحقيق الارتباط الضروري بين العناصر المادية والمادية في محتوى وبنية العمل الفني. يدعو الفن الرقمي إلى إلغاء الحدود بين الفنان والمتلقي وتوسيع حدود التداول. زودت التقنية الرقمية المصمم بخصائص الصمود أمام الأفكار الإبداعية المتخيلة من خلال نظام بصري متنوع الجودة والسرعة في إنتاج مخططات تصميمية تجريبية للجدران تجمع بين آليات التفكير الإبداعي والتقني، ولكن لإطلاق العنان للخيال البشري ليتحرك إلى الأمام وجعله مستحيلاً، وفن الجداريات في العصر الرقمي هو تجسيد للأفكار والخطب التي تسعى إلى إقناع الناس في الجانب الدعائي والإعلامي بسلعة ثقافية قابلة للتداول والتسويق التجاري والفني في بيئة رقمية قادرة على إنتاج الرمز. نسعى إلى إخراج الذاكرة التاريخية للحضارة الإنسانية من بعدها المحلي لتكتسب أبعادا عالمية وإنسانية من خلال الحضور في العوالم الافتراضية والمساهمة في الإبداع العام للإنسانية من خلال الممارسة الواعية للهوية الثقافية وجعلها على اتصال باللغة من الآخر وقريب من إحساس الفنان وإدراكه لذاته ضمن خيال حر يعتمد على الوعي المعرفي والموهبة في إيصال رسالته الثقافية
السمات الأسلوبية في قصة قرآنية - قصة مومن آل فرعون نموذجا
Authors: فروزان فر الأستاذ المساعد الدكتور عبدالله , خطيبي طالب الدكتوراه الباحث علي
Published: August 2023

تعتبر الدراسات الأسلوبية من الدراسات الرئيسية التي فتحت مجالا واسعا في الدراسات اللغوية لأنها جمعت بين المنهج والعلم واحتلت مكانة مهمة في الاعتماد على تحليل النصوص وخاصة النص القرآني. وللقصص القرآنية أماكن في معناها ودلالتها، في حروفها وكلماتها وجملها وأساليبها، مما يجعل القصص القرآنية سببا في الإعجاز القرآني المنهجي. وقد اعتمد الباحث المنهج الوصفي التحليلي لدراسة هذا الموضوع. ولا يقتصر هذا المنهج على جمع الشروحات والحقائق وكتاباتها وتصنيف البيانات والحقائق، بالإضافة إلى التحليل الدقيق والعميق. كما يتضمن بعض الشرح في هذه الطريقة. فاختلط الوصف بالمقارنة في كثير من الأحيان، كما أنه يستخدم أساليب المقارنة والكتابة والشرح بهدف استخلاص النتائج المهمة ومن ثم الوصول إلى تعميمات حول موضوع الدراسة. تبين هذه الدراسة أن الدلالة تنوعت باختلاف السياقات، وأن السمات البنيوية للقصة جاءت من خلال الأفعال والجمل بزمن الأفعال الماضية والمضارعة لتعبر عن أحداث القصة، وأن السمات الصوتية تمثلت بالتكرار والتكرار. الفاصل الزمني الذي يجمع بين الاتساق الفني والتأثير على
تأثير درجات الحرارة في الإصابة بأمراض المفاصل دراسة مقارنة بين محافظات (كركوك، النجف الاشرف، البصرة)
Authors: علي الأستاذ المساعد الدكتور مثنى , عبد الزهرة الباحث احسان
Published: August 2023

أبحاثنا تدخل في مجال المناخ الطبي وهو أحد الفروع الحديثة لعلم المناخ التطبيقي. موضوع مهم شغل وما زال يشغل اهتمامات الباحثين في مختلف التخصصات الجغرافية والمناخية وكذلك الطبية. يتكون البحث من ثلاثة أسئلة بالإضافة إلى الإطار النظري: الخصائص الحرارية لمناخ منطقة الدراسة. خصائص وتوزيع أمراض المفاصل في محافظات منطقة الدراسة. تأثير الخواص الحرارية في تباين أمراض المفاصل في منطقة الدراسة.
Improving Utilization of the Chemotherapy Unit through Implementing the Medication Early Release Project
Authors: Alzahrani Mohsen , Alkaiyat Mohammad , Alshami Mona , Alotaibi Thamer , Meashi Sultan , Enizi Elham Al , Shehata Hussam , Khaleel Ammar , Esbaa Anas Abu , Harbi Reem Al , Alharbi Mohamad
Published: August 2023

Introduction

The outpatient oncology infusion unit is very busy, serving 60 to 70 patients per day. Due to a limited number of nurses, treatment chairs, only one pharmacy hood for bio-hazardous drug preparation, and other factors, patients wait a long time before starting their treatment, which affects the patient experience negatively. We conducted a quality improvement project to reduce the waiting time before starting the treatment, improve the patients' experience, and allow the unit to work more effectively through better resource utilization and accommodating more patients.

Methods

A committee was formed with representatives from oncology nursing and the quality specialist, chemotherapy pharmacy supervisor, data manager, and a medical consultant (team leader). We studied baseline data of patient waiting times from January to March 2019 and the factors that contributed to delays before starting the treatment. The charge nurse identified patients who could safely have their medication released early in the morning at 7 am, enabling the pharmacy to dispense at 8 am without their actual presence being required in the infusion suite (i.e., medication early release program or MERP). Multiple plan-do-study-act (PDSA) cycles were implemented to achieve a wait time from check-in to medication administration of less than 60 minutes. Data collected included check-in time, chair time, vital signs time, administration time, and discharge time. Additionally, reasons for drug wastage were assessed for patients who did not receive the prepared medication. A patient satisfaction survey was conducted with the patients before and after being enrolled in the program.

Results

At baseline, average waiting time for patients receiving similar medications in the MERP was 2 hours and 27 minutes. After the first intervention, average waiting time was reduced to 1 hour and 24 minutes, and small improvements were observed after each PDSA cycl. A major breakthrough occurred after an intensive patient education program and enforcement of strict compliance with the criteria in selecting the patients appropriate for theMERP. Average waiting time wasreduced to ≤ 60 minutes, and in November 2022, it was 30 minutes on average. Drug wastage was identified as a balancing measure. We were successful in reducing drug wastage by implementing several changes and patient education measures and achieved zero wastage. The patient satisfaction survey showed better satisfaction with the new changes.

Conclusion

A positive impact was achieved in this quality improvement project, with a significant reduction in the average waiting time for patients to start receiving chemotherapy. The outcome of this project has been maintained for 4 years and is still ongoing.