bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis de contenido xenofóbico en el fan page del diario La Opinión con relación al retorno de venezolanos periodo 2019-2020
Authors: Villamizar Ramírez Dimelza Johanna
Published: May 2024

Según el boletín de Juan Carlos Mejía Llano (2022), para el mes de mayo de 2022 La red social Facebook cuenta con más de 35.15 millones de usuarios en Colombia, y el descontento que generan más de 50 años de conflicto interno se desemboca en esta red social, incluyendo las muestras de xenofobia hacia los migrantes venezolanos, con datos recientes de 1.300.000 registros biométricos, lo que en palabras de la investigadora Lida Ximena Tabares Higuita, “latente en la red”. Redes sociales de medios de comunicación como La Opinión son foco para los comentarios de usuarios con pensamiento xenofóbico y de rechazo hacia los migrantes venezolanos, como lo prueban estudios previos de investigadores como Santiago Almeida Daza (2020) quien estudió cómo se legitimó la xenofobia a través de la prensa, tomando como objeto de estudio a los diarios La Opinión y El Tiempo, por eso , esta investigación con enfoque metodológico mixto y diseño metodológico no experimental analiza los comentarios de usuarios sobre noticias publicadas en la Fan Page del Diario La Opinión que tratan el tema de la migración; caracterizando el fenómeno mediante un nivel descriptivo para identificar las relaciones entre variables y elaborando un cuadro del tema, mediante un estudio de caso, estableciendo relaciones de causa- efecto con el nivel de investigación explicativa, con el objetivo de detectar cómo se genera xenofobia a través de las interacciones del fan page de La Opinión en torno a las noticias del retorno de migrantes venezolanos, entre marzo y septiembre de 2020. La presente investigación, analizó las formas de interacción, de reacción y de participación, de los seguidores de la página oficial de Facebook de periódico “La Opinión”, (periódico regional, con su sede principal en la ciudad de Cúcuta – capital de Norte de Santander) en el espacio dispuesto para la participación de los internautas referente a los contenidos noticiosos generados por este medio. Esto a partir del auge en el que se encuentran las redes sociales como es el caso de Facebook, en donde los periodistas y muchos medios de comunicación migran a estas plataformas para poder llevar noticias e información a sus diferentes públicos, los cuales optan por estos medios para lograr informarse de manera rápida. Para lograr esto, se realizaron unas fichas de análisis que permitieron determinar los contenidos con los que se generaba una mayor interacción por parte de los usuarios, en donde predominan aquellos contenidos que son redactados deforma breve y con terminología fácil de entender. Por otra parte, se logra determinar el tipo de contenidos que genera más interacción por parte de los usuarios, expuesto a través de compartidos, reacciones y comentarios, estos últimos permiten identificar el tipo de discurso que manejan, el uso del lenguaje verbal y no verbal, el tipo de contenido preferido por ellos y las diferentes formas de participación con los contenidos.
La transformación digital como ventaja competitiva de las pymes mexicanas
Authors: Pérez Escutia Natalia , Fischer de la Vega Laura
Published: May 2024

La adopción de las nuevas tecnologías de la información ha traído consigo visibles cambios en el comportamiento de las personas y de los mercados, por lo que identificar mecanismos que permita a las organizaciones adaptarse de forma continua en un entorno cambiante es un tema de interés. Bajo este contexto, el fenómeno de Transformación Digital (TD) adquiere gran relevancia por los beneficios que genera en las compañías que logran su correcta planeación e implementación. Sin embargo, pese a percibirse la TD como una fuente de cambio continuo que puede ayudar a las organizaciones, existe una falta de consenso respecto a su definición, características y dimensiones. Con el objetivo de definir cuáles son los factores que influyen en el proceso de una TD, así como identificar cuáles son las dimensiones impactadas por la formulación de una estrategia digital, se aplicó una entrevista semiestructurada a seis proveedores de servicios de TD y se utilizó el software Atlas.ti para el proceso de codificación. Se propone una definición de TD, se identifican sus principales fases y una lista de dimensiones impactadas en la formulación de una estrategia digital. Finalmente, se presentan recomendaciones a considerar en un proceso de TD.
Estrategias de marketing en los negocios informales: medios de promoción y publicidad
Authors: Vásquez Quino Ana Laura , Larios Gómez Emigdio
Published: May 2024

El objetivo del presente estudio es analizar las estrategias de marketing que aplican los negocios informales de laciudad de Puebla en México. El tipo de investigación que se emplea en el presente estudio es de carácter tipo mixta(cuantitativa y cualitativa), no experimental, transversal y correlacional. El estudio utilizó la técnica de la encuesta parael análisis cuantitativo y la entrevista a profundidad para el análisis cualitativo. El estudio se concentró en encuestar a157 los dueños y encargados de los establecimientos informales y entrevistar a 22 líderes de estos grupos. Para elanálisis de los datos cuantitativos se empleó el SPSS IBM-Software. Y para los datos recabados en las entrevistas seusó ATLAS.ti v9. El levantamiento de la información se realizó en enero de 2022 a través de dos principales vías comoson presencial y online.
EVALUACIÓN DE LAS CARACTERÍSTICAS SENSORIALES DE UN QUESO FRESCO CON ACEITE MICROENCAPSULADO DE MICROALGA PARACHLORELLA KESSLERI
Authors: Pinchao López Juan Camilo , Viteri Álava Clemencia del Socorro
Published: May 2024

Esta investigación tuvo como objetivo principal la evaluación integral de una matriz láctea enriquecida con aceite microencapsulado extraído de la microalga Parachlorella kessleri. Se establecieron tres objetivos específicos para abordar diferentes aspectos del proyecto. En primer lugar, se centró en la formulación y estandarización de la matriz láctea con la adición de aceite microencapsulado de Parachlorella kessleri. A través de un enfoque experimental, se logró establecer una formulación óptima (es decir valores altos en microencapsulado y bajo en sal) y las condiciones de fabricación necesarias para producir queso fresco enriquecido con este aceite microencapsulado, implicando la manipulación de variables clave en la producción. Posteriormente se enfocó en la evaluación de las características nutricionales y fisicoquímicas del producto resultante. Se analizaron parámetros como la humedad, sólidos totales, pH y perfil de ácidos grasos para comprender mejor la composición nutricional del queso fresco con la adición del aceite microencapsulado, destacando su contribución a los ácidos grasos esenciales, como los omega-3. El último aspecto de esta investigación fue la evaluación sensorial del queso fresco enriquecido. A través del análisis sensorial, se evaluaron los atributos de sabor, textura y olor del producto final, proporcionando una comprensión precisa de la percepción sensorial por parte de los consumidores, lo que es esencial para evaluar su aceptación en el mercado. Este artículo presentará los resultados de la evaluación sensorial que respaldaron la viabilidad de la inclusión del aceite microencapsulado de Parachlorella kessleri en la matriz láctea. El queso fresco enriquecido mantuvo características organolépticas similares a las de un queso fresco tradicional, lo que sugiere su potencial como una opción atractiva y saludable para los consumidores en busca de productos lácteos innovadores y nutritivos.
Avances en métodos de muestreo para la caracterización de microplásticos en ecosistemas fluviales
Authors: Salazar Sanchez Margarita-del-Rosario , Imbachi Hoyos Rosmery Carolina , Solanilla Duque José Fernando
Published: May 2024

Este artículo de investigación presenta una revisión bibliográfica exhaustiva sobre los métodos de muestreo aplicados en la evaluación de microplásticos en ecosistemas fluviales. La creciente preocupación en torno a la contaminación por microplásticos en entornos acuáticos exige enfoques de muestreo rigurosos. El objetivo principal de este estudio es evaluar críticamente las metodologías existentes, destacando sus fortalezas y limitaciones. Al examinar técnicas de muestreo convencionales y emergentes, la revisión busca ofrecer recomendaciones para mejorar futuras investigaciones. A través de un análisis meticuloso de investigaciones previas, este estudio tiene como objetivo mejorar la comprensión de la presencia de microplásticos en sistemas fluviales.
БЕЗПЕКОВІ ГАРАНТІЇ ДЛЯ УКРАЇНИ: ОЧІКУВАННЯ ТА РЕАЛЬНІСТЬ
Authors: Тодоров Ігор , Тодорова Наталія
Published: May 2024

У статті висвітлено міжнародний вимір національної безпеки України. Розглянуто можливість зовнішніх гарантій у сфері безпеки. Визначено зовнішній чинник у національній безпеці України з початку 1990-х років. Проаналізовано новітні двосторонні безпекові угоди України, укладені на початку 2024 року. Доведено безальтернативність євроатлантичного курсу як реальної можливості гарантувати безпеку нашої держави. Перспектива набуття членства України в НАТО спроможна зупинити сучасну російську агресію на українських умовах та сприяти спільній перемозі над Росією. Вступ України до НАТО може стати історичним кроком у розвитку Альянсу і сприяти створенню нової системи колективної безпеки у світі. Швидка євроатлантична інтеграція України може бути вмотивована кількома аргументами: врахування унікального військового досвіду України у веденні широкомасштабної війни; розгляд членства як засобу внеску до припинення конфлікту та зняття фінансового тягаря з членів Альянсу; діяльність України відповідно до Стратегічної концепції НАТО в боротьбі з російською загрозою. Ефективна протидія Росії вимагає від колективного Заходу повної мілітаризації як України, так і самого Заходу. Головним має бути стратегічне бачення поразки Росії. Агресію проти України слід розглядати як стратегічну атаку з боку Москви на західну спільноту. В сучасному контексті українського спротиву формуються перспективи світового порядку на найближчі десятиліття, Ключовим аспектом майбутнього світу має стати дезінтеграція Росії як головної загрози людству.
РЕАЛІЗАЦІЯ ПРОГРАМИ РЕЛОКАЦІЇ ПІДПРИЄМСТВ В УКРАЇНІ
Authors: Гапак Наталія , Чубарь Оксана
Published: May 2024

У статті розглянуто організаційно-економічні та окремі аналітичні аспекти запровадження із початком російсько-української війни Програми релокації бізнесу із зони бойових дій, яка передбачає державну допомогу в підборі площ для розміщення виробництва; перевезенні й розселенні персоналу; доборі працівників у місцях дислокації після переїзду. Зроблено висновок про загалом позитивні результати реалізації Програми як для конкретних підприємств і їх власників, так і для держави в цілому, оскільки це сприяло збереженню виробничих потужностей, робочих місць та економічного потенціалу країни (хоча б частково). У Львівській та Закарпатській областях, куди було релоковано найбільшу кількість підприємств, відбулося поліпшення показників економічної динаміки, зростання кількості робочих місць і податкових надходжень. У загальній кількості релокованих до Закарпатської області суб’єктів господарювання (280 підприємств різних форм власності) найбільшу частку займають підприємства сфери послуг (32,9 %), ІТ індустрії (30,7 %) та переробної промисловості (26,4 %).
На основі систематизації інформації з відкритих публічних джерел зроблено висновок про те, що кожен регіон України у створенні привабливих умов для бізнесу з прифронтових регіонів пропонував специфічні важелі для залучення на свої території. Важливим компонентом втілення в життя Програми стало налагодження комунікацій зацікавлених сторін, консультативне забезпечення з використанням сучасних інформаційних ресурсів.
Реалізація вказаної  Програми, як і інших механізмів державної підтримки бізнесу в умовах війни, визнається експертами недостатньо ефективною через бюрократичні складнощі та розтягнутість у часі доступу до відповідних послуг, обмеженість фінансових ресурсів для підтримки і супроводу як безпосередньо процесу переміщення, так і на етапі розміщення і початку господарювання на нових локаціях. Недостатньою є інформаційна та консультаційна підтримка бізнесу на різних етапах.
La incursión de los profesionales de la información en vigilancia tecnológica e inteligencia estratégica en Argentina
Authors: Pandolfo Milagros , Hernandez Alicia Beatriz
Published: May 2024

La vigilancia tecnológica y la inteligencia estratégica (VTeIE) son áreas de influencia para la bibliotecología y ciencia de la información (ByCI), ya que implican funciones de búsqueda, gestión y diseminación de información especializada. Representan una expansión de las incumbencias profesionales dentro del ámbito científico y tecnológico, a la par que involucran necesariamente un enfoque interdisciplinario. El presente estudio describe la vinculación existente entre el perfil del profesional de la información, el proceso de VTeIE y el Sistema Nacional de Ciencia, Tecnología e Innovación (SNCTI) en Argentina. Para ello se llevaron adelante los relevamientos y el análisis de los sitios web oficiales de los organismos públicos que lo componen y se realizaron entrevistas y cuestionarios a expertos. Los resultados revelaron que los profesionales de la información componen el 31% de los equipos de trabajo analizados y que actualmente se encuentran asumiendo un rol protagónico en los organismos del SNCTI que realizan este tipo de procesos, generando productos con alto valor agregado para la gestión del conocimiento y la innovación. En conclusión, estos hallazgos destacan el perfil tecnológico actual de ByCI, la importancia de su participación en el campo científico y su papel fundamental en el monitoreo estratégico de información a través de la VTeIE.
Effect of a buckwheat extrudate addition on the quality of multicomponent albumin concentrates
Authors: Grek Olena , Onopriichuk Olena , Tymchuk Alla , Soloviov Nikita
Published: May 2024

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Możliwości terapeutyczne w leczeniu jaskry otwartego kąta i ich zastosowanie w oparciu o najnowsze wytyczne
Authors: Misiuk-Hojło Marta , Tomczyk-Socha Martyna
Published: May 2024

Jaskra to neuropatia nerwu wzrokowego, która charakteryzuje się typowym uszkodzeniem nerwu wzrokowego ze stopniowym zanikiem komórek zwojowych siatkówki i ubytkami w polu widzenia. Celem farmakoterapii jaskry jest obniżenie ciśnienia wewnątrzgałkowego i zmniejszenie dobowych fluktuacji. Obecnie w leczeniu jaskry pierwotnej otwartego kąta w Polsce stosujemy cztery grupy leków: antagonistów receptorów β-adrenergicznych, analogi prostaglandyn, agonistów receptorów α-adrenergicznych i inhibitory anhydrazy węglanowej. Lekami pierwszego rzutu, według wytycznych Polskiego Towarzystwa Okulistycznego, są analogi prostaglandyn/prostamidy. Jeśli rozważane jest dołączenie drugiego leku do prostaglandyn, należy pamiętać, że brymonidyna obniża ciśnienie wewnątrzgałkowe silniej niż dorzolamid i brynzolamid, a podobnie jak tymolol. Leki zawierające dwie substancje czynne są tak samo skuteczne jak substancje podawane w dwóch osobnych preparatach, dlatego korzystne jest stosowanie preparatów złożonych zamiast zakraplania dwóch różnych leków.
The results of surgical treatment to correct eyelid retraction with blepharotomy – preliminary report
Authors: Różycki Radosław , Ulaszewska Katarzyna , Różycka Katarzyna , Chamernik Alan , Różycka Małgorzata , Nesterowicz Piotr
Published: May 2024

The study presents early results of the surgical treatment of patients with fixed upper eyelid retraction exceeding 1 mm as a complication of Graves’ disease, trauma, or high myopia.
10 patients (8 women and 2 men), with an average age of 45, participated in the study. A total of 17 upper eyelids were operated on using the full-thickness blepharotomy method. According to the EUGOGO scale for the surgery 2 patients had mild retraction, 7 – moderate retraction, and 1 – severe retraction. The procedures were performed under local anesthesia, following current knowledge and described operative techniques.
Each operated patient achieved both aesthetic and functional improvement compared to the baseline. The results were evaluated based on the reduction of the upper eyelid relative to the corneal limbus, reaching a level covering the corneal limbus. The average satisfaction score obtained was 8 points in 0–10-point scale.
Blepharotomy is an effective therapeutic procedure for upper eyelid retraction, reducing eye exposure symptoms and restoring a normal appearance of the eyelids. The procedure has rare serious side effects, and patients are content with the results.
The influence of high additions in multifocal contact lenses for myopia control on binocular vision
Authors: Kropacz-Sobkowiak Sylwia , Przekoracka-Krawczyk Anna , Michalski Andrzej , Olszewski Jan , Wasilewska Klaudia
Published: May 2024

Objectives: This study aimed to investigate the influence of soft multifocal contact lenses with high additions designed for myopia control on binocular vision in young adults.
Methods: A prospective randomized, double-blind study including 24 subjects aged between 18 and 36 years. Subjects were divided into two groups. The first group wore multifocal soft contact lenses (MFSCLs) with a 3.0 mm central zone diameter, while the second group wore contact lenses with 4.5 mm central zones. Each subject was fitted with two MFSCLs: one with +2.00 D and the other with +4.00 D peripheral addition power and, additionally, with plano single vision contact lenses (SVCLs). Phoria at a distance and near, distance and near vergence ranges, vergence facility at near, stereopsis at near, and fixation disparity at near were measured in each study lens type.Results: No significant influence of addition on distance phoria was found in either group (p = 0.446 and p = 0.317, for 3 mm and 4.5 mm central zone diameter, respectively). Additionally, no significant difference was observed for any MFSCLs and SVCLs in near phoria (p = 0.320), near vergence facility (p = 0.197), or near fixation disparity (p = 0.203). A decline in fusional vergence ranges at a distance in the base-out direction was noted in subjects wearing +4.00 D addition compared to +2.00 D addition (p = 0.002) and plano lenses (p = 0.014). Both additions reduced fusional vergence ranges at near the base out (p = 0.020) and shifted vergence ranges more in the exophoria base in directions (p = 0.014).
Conclusions: The study showed that MFSCLs with high additional power in the periphery have only a marginal impact on the binocular functions.
Mobile healthcare application on Android OS using cloud computing
Authors: Omran Nahla F.
Published: May 2024

Healthcare mobile applications satisfy different aims by frequently exploiting the built-in features found in smart devices. The accessibility of cloud computing upgrades the extra room, whereby substances can be stored on external servers and obtained directly from mobile devices. In this study, we use cloud computing in the mobile healthcare model to reduce the waste of time in crisis healthcare once an accident occurs and the patient operates the application. Then, the mobile application determines the patient’s location and allows him to book the closest medical center or expert in some crisis cases. Once the patient makes a reservation, he will request help from the medical center. This process includes pre-registering a patient online at a medical center to save time on patient registration. The E-Health model allows patients to review their data and the experiences of each specialist or medical center, book appointments, and seek medical advice.
Digital Natives' Mobile Learning Adoption in terms of UTAUT-2 Model: a Structural Equation Model
Authors: Talan Tarik , Doğan Yunus , Kalinkara Yusuf
Published: May 2024

This research investigates university students' intentions and behaviors regarding the adoption of mobile learning tools in higher education, with a focus on the Unified Theory of Acceptance and Use of Technology (UTAUT-2) model. A sample of 541 university students from a state university in the Southeastern Anatolia Region of Turkey participated in this study. Structural equation modeling was employed to assess students' mobile learning adoption levels, and statistical analyses were conducted accordingly. The findings indicate a moderate level of mobile learning adoption among the students. The study reveals that students employ various strategies while using mobile tools for learning. Notably, among digital natives, intention to use mobile devices is significantly influenced by habit, hedonic motivation and effort expectancy. Additionally, the study identifies a significant relationship between the use behavior variable and facilitating conditions. The research also examines regulatory effects within the model, demonstrating that age moderates the relationship between habit and use behavior. Furthermore, gender has a moderating effect on the relationship between facilitating conditions and behavioral intention, as well as between hedonic motivation and behavioral intention. Finally, experience moderates the relationship between habit and use behavior, as well as between behavioral intention and use behavior.
Coronary calcified nodules versus nonnodular coronary calcifications: a systematic review and meta-analysis
Authors: Oliveri F. , Van Oort M.J.H. , Al Amri I. , Bingen B.O. , Van der Kley F. , Jukema J.W. , Jurado-Roman A. , Montero Cabezas J.
Published: May 2024

Background

Percutaneous coronary intervention (PCI) on severely calcified coronary lesions is challenging. Coronary calcified nodule (CN) refers to an eccentric and protruding coronary calcification associated with plaque vulnerability and adverse clinical events. This study aims to conduct an extensive review of CNs, focusing on its prognostic impact in comparison with nonnodular coronary calcification (N-CN).

Method

A systematic literature review on PubMed, MEDLINE, and EMBASE databases was conducted for relevant articles. Observational studies or randomized controlled trials comparing CNs and N-CNs were included.

Results

Five studies comparing CNs and N-CNs were pertinent for inclusion. The total number of individuals across these studies was 1456. There were no significant differences in the baseline demographic, clinical, and angiographic data between the CN and N-CN groups. Intracoronary imaging was always utilized. At follow-up, CNs were associated with significantly increased, target vessel revascularization [odds ratio (OR) 2.16; 95% confidence interval (CI): 1.39–3.36, P-value < 0.01, I
2 = 0%] and stent thrombosis (OR 9.29; 95% CI: 1.67–51.79, P-value = 0.01, I
2 = 0%) compared with N-CN. A trend for greater cardiac death was also assessed in the CN group (OR 1.75; 95% CI: 0.98–3.13, P-value = 0.06, I
2 = 0%).

Conclusion

CN has a significantly negative impact on outcomes when compared with N-CN.
Lyophilised protein formulations as a patient-centric dosage form: A contribution toward sustainability paradigm
Authors: Žiberna Maja Bjelošević , Grabnar Pegi Ahlin , Gašperlin Mirjana , Matjaž Mirjam Gosenca
Published: May 2024

At present, society has embraced the fact apropos population aging and climate changes, that demand, amongst others, innovative pharmaceutical technologies, emphasising the development of patient-specific delivery systems and thus the provision of efficient and sustainable drugs. Protein drugs for subcutaneous administration, by allowing less frequent application, represent one of the most important parts of the pharmaceutical field, but their development is inevitably faced with obstacles in providing protein stability and suitable formulation viscosity. To gain further knowledge and fill the gaps in the already constructed data platform for the development of monoclonal antibody formulations, we designed a study that examines small model proteins, i.e., bovine serum albumin. The main aim of the presented work is to evaluate the effect of protein concentrations on critical quality attributes of both, pre-lyophilised liquid formulations, and lyophilised products. Through the study, the hypothesis that increasing protein concentration leads to higher viscosity and higher reconstitution time without affecting the stability of the protein was confirmed. The most important finding is that sucrose plays a key role in the lyophilisation of investigated protein, nevertheless, it can be predicted that, to ensure the beneficial effect of mannitol, its amount has to prevail over the amount of sucrose.
Lipid-based systems with precipitation inhibitors as formulation approach to improve the drug bioavailability and/or lower its dose: a review
Authors: Kovačević Mila , Gašperlin Mirjana , Pobirk Alenka Zvonar
Published: May 2024

Lipid-based systems, such as self-microemulsifying systems (SMEDDS) are attracting strong attention as a formulation approach to improve the bioavailability of poorly water-soluble drugs. By applying the “spring and parachute” strategy in designing supersaturable SMEDDS, it is possible to maintain the drug in the supersaturated state long enough to allow absorption of the complete dose, thus improving the drug’s bio-availability. As such an approach allows the incorporation of larger amounts of the drug in equal or even lower volumes of SMEDDS, it also enables the production of smaller final dosage forms as well as decreased gastrointestinal irritation, being of particular importance when formulating dosage forms for children or the elderly. In this review, the technological approaches used to prolong the drug supersaturation are discussed regarding the type and concentration of polymers used in liquid and solid SMEDDS formulation. The addition of hypromellose derivatives, vinyl polymers, polyethylene glycol, polyoxyethylene, or polymetacrylate copolymers proved to be effective in inhibiting drug precipitation. Regarding the available literature, hypromellose has been the most commonly used polymeric precipitation inhibitor, added in a concentration of 5 % (m/m). However, the inhibiting ability is mainly governed not only by the physicochemical properties of the polymer but also by the API, therefore the choice of optimal precipitation inhibitor is recommended to be evaluated on an individual basis.
Advancing Drone Swarm Simulation: A Comprehensive System for Real-Time Control and Dynamic Interaction
Authors: Herich Dušan , Vaščák Ján
Published: May 2024

The rapid evolution of unmanned aerial vehicles (UAVs), has significantly advanced their capabilities, enabling complex operations that can be enhanced through swarm intelligence. This paper introduces a drone swarm simulator designed to model, analyze, and optimize the cooperative behaviors of drone swarms in diverse operational environments to provide a realistic and scalable platform for the simulation of drones, incorporating real-world physics, communication constraints, and autonomous decision-making algorithms.
Genetic Analysis of Three Geographically Secluded Populations of Nile TilapiaOreochromis niloticus(Cichlidae)
Authors: Popoola Omoniyi Michael
Published: May 2024

Nile tilapiaOreochromis niloticusis one of the most important fishery resources and a valuable fish species for aquaculture programmes. It is found in almost all waters and is widely dispersed. Several natural populations of this species have been impacted by genetic pollution despite their significant economic relevance. Understanding population structure is a crucial first step in protecting this species in its native habitats as well as in choosing which wild stocks to use in hatchery initiatives. To demonstrate the genetic-population structure of this species, genetic differences among three geographically secluded populations ofO. niloticuswere investigated utilizing mitochondrial DNA cytochrome b gene sequences. The results were used to estimate the levels of genetic variability within and among the populations. The 56 cyt b (821 bp) sequences analysis revealed 21 haplotypes, with a nucleotide diversity of 0.0510 and a haplotype diversity of 0.881. In each of the populations, seven (7) singleton variable sites and 19 informative-parsimony sites, genetic diversity could be identified and few population haplotypes were found, indicating a minor genetic distinction between them. For the purpose of conservation and/or Nile tilapia breeding programmes, this information would assist in choosing the fish populations that maintain greater genetic variation inO. niloticus.
Beyond the Stereotypes: Unveiling Signs in “Flip the Script” Video Champaign for Sustainable Development Goals
Authors: Dewi Ni Made Sinta , Juniartha I Wayan
Published: May 2024

This study employs semiotic analysis to examine the verbal and visual signs within the "Flip the Script" video campaign and explore their interplay in conveying the campaign's intended message. Additionally, the research categorizes the United Nations Sustainable Development Goals (SDGs) depicted in the campaign, drawing from Chandler's (2007) and Leech's (1981) theories The findings highlight the presence of connotative meanings that significantly enhance communication strategies. Through linguistic and visual exploration, the study analyzes how signs and metaphor-driven words resonate deeply with viewers. The process of categorizing SDGs bolsters the campaign's mission of advancing sustainable development, harnessing semiotics to foster nuanced comprehension and forge meaningful connections. The findings of the study shed light on how the campaign video effectively confronts stereotypes and disrupts ingrained societal biases by presenting diverse narratives. This contribution ignites inclusive dialogues and steers positive transformation, enhancing the understanding of the campaign's impact on societal perceptions and behaviors.
ANALISIS TINDAK TUTUR REPRESENTATIF PADA DAFTAR PUTAR “MKU BAHASA INDONESIA” DALAM CHANNEL RAHMAT PETUGURAN
Authors: Al Farizi Muhammad Akmal , Nurul Azizah Hanifah Rifdah , Putri Silviana Annisa , Linawati Agustin , Utomo Asep Purwo Yudi
Published: May 2024

Tindak tutur ialah termasuk didalam unsur ataupun komponen pragmatik yang didalamnya dilibatkan terkait pembicara dan juga pendengar. Dalam Tindak tutur terbagi dalam 5 pengelompokan besar antara lain; tindak tutur representatif, komisif, direktif, ekspresif, deklaratif. Dalam artikel penelitian ini hanya membahas salah satu dari jenis tindak tutur yakni tindak tutur representatif. Tindak tutur representatif adalah tindak tutur yang mengikat penutur pada keabsahan tuturan yang diucapkan. Tuturan tersebut membuat penulis tertarik untuk menjadikan bahan kajian karena dalam tindak tutur representatif terdapat banyak kategorinya. Tindak tutur representatif tidak hanya dapat ditemukan pada tuturan langsung saja, akan tetapi dapat juga ditemukan di akun media sosial, seperti media youtube. Oleh karena itu, dalam penelitian ini memiliki tujuan guna mengkaji mengenai tindak tutur representatif pada beberapa video youtube daftar putar dalam channel Rahmat Petuguran, salah satunya dalam video yang berjudul "MKU Bahasa Indonesia". Metode yang peneliti gunakan untuk menyajikan hasil analisis data adalah metode informal, dimana hasil tuturan yang dianalisis tidak menggunakan kata baku secara keseluruhan dan pendekatan dalam penelitian ini berwujud pendekatan pragmatik. Teknik pengumpulan data dalam artikel ini menggunakan teknik simak yang terdiri dari dua teknik yakni teknik simak bebas libat cakap,  teknik catat, serta teknik pustaka. Teknik pustaka ialah teknik yang mencakup kegiatan membaca, menyimak, mencatat, dan menganalisis. Hasil pada penelitian ini berupa tindak tutur menyatakan, menunjukkan, menyebutkan, menginformasikan, menuntut, menyarankan, menjelaskan, berspekulasi, dan memberikan contoh. Dengan adanya artikel ini, diharapkan pembaca bisa menemukan makna tindak tutur representatif pada beberapa video youtube dalam channel Rahmat Petuguran yang nantinya bisa dijadikan referensi bagi pembaca.
Antioxidant and Antimicrobial Activities of Some New Synthesized Triazole, Thiazolone, and Thiazine Containing Fused Rings of Imidazopyridine
Authors: Hamd Amera H. , Al-Lami Naeemah
Published: May 2024

Several heterocyclic compounds bearing an imidazo(1,2a)pyridine moiety have been synthesized in this work, including triazole, thiazol, and thiazolone. This was done by condensation of 2-aminopyridine with 2-aminopyridine with 4-bromophencyl bromide or 4-phenylphencyl bromide to produce 2-substituted phenyl imidazo(1,2a)pyridine compounds 1 and 2. The Vilsmeier-Haak reaction was used to create the aldehyde group at position 3 of the 2-substituted phenyl imidazo(1,2a)pyridine ring (3 and 4). The reaction of compounds 3 and 4 with thiosemicarbazide afforded thiosemicarbazone derivatives 5 and 6 in 66 and 70% yields, respectively. These derivatives (5 and 6) were then subjected to three different cyclization reactions to obtain 1,3-thiazolone (7 and 8), 1,2,4-triazole (9 and 10), and 1,3-thiazole (11 and 12) derivatives. The FT-IR spectroscopy was used to confirm the structure of these derivatives, and the 1H NMR spectroscopy was used for some of them. A few of the produced compounds were examined for antimicrobial and antioxidant activities
Intelligent Surveillance Systems for Fire Detection in Open Areas: A Survey
Authors: Mohammed Muthanna S. , Abbas Amel H. , Abdullah Nada A.Z.
Published: May 2024

With the growth of open areas comes an ever-increasing risk of fire. However, there is a problem with the present approaches to fire detection, which rely on smoke sensors for wide regions. The advent of video surveillance systems has greatly improved our ability to detect smoke and flames coming from a distance and reduced this risk. Point sensors are slower at detecting fires than cameras when image processing is used. Moreover, using this video and image data presents processing challenges due to the enormous volume of data involved. Several approaches have recently been put forth to address this issue and distinguish between fire and smoke. Earlier methods included image processing algorithms for flame and smoke detection as well as motion-based estimation of smoke. Recently, a variety of techniques have been put forth using deep learning and convolutional neural networks (CNNs) to predict and automatically identify fire and smoke in videos and images. In this study, we review previous studies of fire/smoke detection systems based on machine vision and deep learning. The foundations of image processing techniques, CNN, and their applicability to video smoke and fire detection are explained. A discussion of current data sets and an overview of recent methods applied in this field The difficulties and potential solutions for advancing the application of CNN in this field are discussed. Then a comparison for researchers in the last years based on the dataset, year, technique, limitation, and accuracy they got The CNNs have been found to have a high potential for detecting open areas, and improved development can help create a system that would significantly reduce the loss of human life and property. Remarks for future work were concluded.
ANALISIS KEWENANGAN GUBERNUR DKI JAKARTA DALAM MENETAPKAN KEPUTUSAN UPAH MINIMUM PROVINSI TAHUN 2022
Authors: Sandy Maulana Yusuf Saidi  , Tri Sulistyowati
Published: May 2024

This study is based on previous work by the Governor of DKI Jakarta, who, in his 2021 Decree No. 1359, first decided on a minimum salary by looking at government regulations pertaining to salaries. Afterwards, Decree Number 1517 superseded it, disregarding the applicable government wage regulations. Examining whether or not Governor DKI Jakarta's Decision Number 1517 of 2021, which sets the minimum salary for 2022, conforms with legal requirements, and whether or not the Governor has the jurisdiction to decide minimum wage choices based on extant legislation are the problems that this study seeks to address. Using secondary data culled from a variety of sources, including main legal resources like statutes and secondary legal materials like books and journals, this study takes a descriptive-analytical method. Qualitative research and inference led to the conclusion that Law 23 of 2014 on Regional Governments grants the Governor of DKI Jakarta the authority to establish the provincial minimum salary for 2022. Unfortunately, this decision was not made in accordance with the processes laid forth in Law No. 12 of 2011 on the Formation of Legal standards.
PEMBANGUNAN BUMI PERKEMAHAN TANPA DOKUMEN AMDAL DI KABUPATEN GARUT (STUDI PUTUSAN NOMOR 2251 K/PidSus- LH/2020)
Authors: Deannova Rafli Subagio  , Narita Adityaningrum
Published: May 2024

The construction of a campground in Garut Regency has caused legal problems, because it does not have an AMDAL document and environmental permits. The problems of this article are: whether the construction of the campground carried out by the head of DISPORA to fulfill environmental permits is in accordance with the Law on Environmental Protection and Management (UUPPLH) and what legal consequences arise from development in natural resource conservation areas without AMDAL documents. This research is a normative legal research and is descriptive in nature. The results of the research and discussion show that the AMDAL document is a legal instrument that must be made by every person in charge in a business/activity that has an important impact and violations result in the revocation of environmental permits. The conclusion of this research, namely: The construction of the campground carried out by the Head of DISPORA is not in accordance with Article 36 paragraph (1) of the UUPPLH. The Head of DISPORA Garut Regency has never made an AMDAL Document to the Environmental Agency and did not apply for an Environmental Permit to BPMPT so that the Head of DISPORA was sentenced under Article 109 jo. Article 116 paragraphs (1) and (2) of UUPPLH for non-compliance in making AMDAL documents.
Pengaruh Komite Audit Dan Kepemilikan Asing Terhadap Nilai Perusahaan Yang Dimediasi Oleh Sustainability Report
Authors: Holly Anthony , Tangke Paulus , Jao Robert , Tanri Eveline Pricilia
Published: May 2024

The purpose of this study is to examine the effect of audit committee, foreign ownership, and sustainability reports on firm value, and examine the effect of audit committees and foreign ownership on firm value mediated by sustainability reports.This study uses agency theory which explains the agency relationship between principals and agents, as well as stakeholder theory which explains the relationship between companies and their stakeholders. This study uses a purposive sampling method, namely a sample selection method that meets predetermined criteria so that the number of samples that meet the criteria is 33 companies for each period from the entire population of non-financial companies listed on the Indonesia Stock Exchange in 2019-2021. The data analysis method used in this study is path analysis and mediation hypothesis testing using the sobel test. The results of this study indicate that the audit committee has a positive and significant effect and foreign ownership has a positive but not significant effect on the sustainability report. The audit committee has a positive but not significant effect on firm value, and foreign ownership and sustainability report have a positive and significant effect on firm value. This study also shows that sustainability reports are able to mediate the effect of audit committees on firm value, while sustainability reports are not able to mediate the effect of foreign ownership on firm value.

Keywords : Foreign Ownership, Audit Committee, Firm Value, Sustainability Report
Psoriasis in pediatric dermatological clinical practice: diagnosis and management
Authors: Sidorenko Olga A. , Anisimova Liudmila A. , Starostenko Vyacheslav V. , Grebennikova Svetlana V.
Published: May 2024

The relevance of this topic is confirmed by the widespread psoriasis prevalence. Psoriasis in children has severe forms growth and diagnostic difficulties. It is crucially important to examine histologically the skin especially in pediatric dermatological clinical practice. According to our observations Pityriasis Rubra Pilaris has become one of the most frequent dermatoses with which differential diagnosis of psoriasis has to be carried out. A clinical dermatosis observation in a 13-year-old girl is described. The disease was similar to the manifestations of Pityriasis Rubra Pilaris. The results of the affected skin biopsy study did not exclude this diagnosis. The clinical and morphological manifestations of the dermatosis could be effected by steroid therapy. Subsequent dynamic observation and histological examination allowed us to diagnose psoriasis. Current data is collected and presented. The choice of external therapy in pediatric practice is a controversial topic. Clinical results of the Activated Zinc Pyrithion external forms use in the psoriasis treatment are presented.
A Pilot Study of Serum Adenosine Deaminase Levels in Benign and Malignant Breast Lumps at a Tertiary Care Hospital
Authors: Parameswaran Rashmi , Satyanarayana V. , Ashwini R. K.
Published: May 2024

Objectives:

The primary objective of the study is to measure the serum ADA levels in benign and malignant breast lumps. The secondary objective is to compare the serum ADA levels in benign and Malignant breast lumps, and to assess the use of serum ADA levels as a potential biochemical indicator for the diagnosis of breast carcinoma.

Materials and Methods:

This is a descriptive observational study which is being conducted at Rajarajeswari Medical College and Hospital for 3 months. The patients presenting with breast lumps were subjected to a clinical examination of both breasts and axillae, which were then confirmed by radiological investigations such as mammograms or sonomammograms for a final diagnosis. Blood samples were drawn for the measurement of serum ADA activity, which was measured at 37°C according to the method of Giusti and Galanti, based on the Berthelot reaction. The statistical analysis was done using descriptive and inferential statistics. Yamane’s formula was used to calculate the sample size of 50 patients.

Results:

Out of the 50 cases included in this study, 60% of the patients have malignant breast lumps and 40% of the patients have benign breast lumps. Out of the malignant cases (breast imaging-reporting and data system stage 4 and above), 11.1% are found to have abnormally high serum ADA levels (>24 U/L), while 0% of the benign cases have abnormal serum ADA values (<24 U/L).

Conclusion:

According to the findings in this study, serum ADA values are similar in range for benign and malignant breast lumps. Only 11.1% of the malignant cases show a rise in serum ADA levels, which is not adequate for the diagnosis of breast carcinoma. Hence, contrary to previous studies, serum ADA levels are not a specific indicator for the diagnosis of breast carcinoma. Limitations in this study may include a small sample size and the inclusion of pre-operative cases. A larger sample size may substantiate the result with respect to the use of serum ADA levels as an indicator of breast carcinoma.
Unrealized Monographic Project of M.N. Kufaev “Bibliology” (1926)
Authors: Samarin Alexander Yu.
Published: May 2024

The article is devoted to the manuscript prospectus of the anticipated book “Bibliology” by M.N. Kufaev (1888—1948), which is kept in the personal archive fund of N.Yu. Ulyaninsky (1872—1937) in the Manuscripts Department of the Russian State Library. It was prepared in the summer of 1926 and was intended for the State Publishing House. In the document M.N. Kufaev outlined an expanded understanding of bibliology as a general philosophy and methodology of book studies, which he had formulated earlier in his work Philosophy of the Book. The prospectus gives an idea of M.N. Kufaev’s ideas in the field of book terminology and classification of book disciplines. In particular, the document testifies to the scientist’s desire to use the concept of “book culture”, to develop the theme of “book studies and Marxism”, to pay attention to the economics of book studies.
Energy Future of the Russian Far East: Low-Carbon Development Potential
Authors: Dyomina O.V. , Gulidov R.V.
Published: May 2024

The paper discusses the current and future- oriented models of development of the energy sector of the Russian Far East. We demonstrate that the current model is aimed at maximizing the external rent and resource rent, and it is characterized by a low priority of the environmental policy and actually ignores the global trend of the energy transition. We assess the risks of sticking to the current model and "no action taken" development of the energy sector. We review institutional conditions and identify barriers to the development of low- and zero-carbon technologies in the current model. The future-oriented model aims to preserve the advantages of the current model and complement it with high-tech production facilities in the energy sector along with the transformation of the economy and energy in line with the energy transition trends. It is nowadays common to distinguish between two main groups of technologies that are part of the future-oriented model: hydrogen technologies and renewable energy. By focusing on the former, we analyze the conditions for the development of hydrogen technologies as applied to the subjects of the Far Eastern Federal District and identify competitive advantages and limiting factors.
Guiding the rational design of biocompatible metal-organic frameworks for drug delivery using machine learning
Authors: Menon Dhruv , Fairen-Jimenez David
Published: May 2024

The poor prognosis of cancer and other diseases has often been linked to challenges pertaining to drug accessibility and delivery. To combat these challenges, nanotechnology has witnessed decades of intensive research, resulting in the development of innovative nanoscale strategies for improving therapies and minimizing the side effects of existing drugs. Notably, multiple nanocarriers have obtained clinical approval as proficient drug delivery systems. Metal-organic frameworks (MOFs) have emerged as an interesting paradigm owing to their tuneable porosity, structural diversity, and ease of external surface functionalization. Compared to other drug delivery systems, state-of-the-art MOFs can encapsulate up to 50 times higher quantities of drugs per unit of mass while showing very long release times. Nevertheless, for their translation into clinical applications, concerns regarding MOF biocompatibility necessitate comprehensive mitigation. Unfortunately, experiments are resource and time-intensive, while modeling approaches fail to capture the behavior of MOFs in intricate biological systems. To overcome these barriers, we review here recent advances on biocompatibility and propose a novel computational pipeline guided by machine learning (ML). This is designed to expedite the assessment of potential MOF toxicity based on the chemical properties of their precursors. Interpretable ML models were built on a database of over 35,000 organic molecules, predicting the potential toxicity of MOF linkers with 83% accuracy. Additionally, we established a comprehensive database cataloging the toxicity of MOF metallic centers. Leveraging these, we have screened the Cambridge Structural Database (CSD) containing 86,000 non-disordered MOFs, identifying existing and future promising candidates with minimal toxicity profiles for drug delivery applications. Beyond high-throughput screening, the developed models shed light on the chemical landscape associated with high biocompatibility precursor molecules, enabling the derivation of guidelines for the rational design of biocompatible MOFs. This framework thus expedites the identification of biocompatible materials, while facilitating deeper insights into their underlying chemistry. The protocols developed here will be easily transferred to other systems, accelerating associated research timescales.