bluuebunny/crossref_metadata_2025 huggingface dataset:
CICATRICIAL ECTROPION REPAIR DUE TO TRAUMA : A CASE REPORT
Authors: Rino Agustian Praja  , Hendrianti  , Mardijas Efendi
Published: February 2024

Introduction : Cicatricial ectropion is a complication that can occur after trauma. Scar tissue formation causes anterior lamellae shortening (skin and orbicularis muscle), resulting in outward lid margins rotation.

Case Illustration : A 16 y.o male patient came with complaints of the left upper and lower eyelids folding outwards since 3 months ago after trauma, watery eye. Examination VOD 20/20, VOS 20/50. Scar on the superior and inferior lids, the inferior lid margin is folded out, inferior tarsal conjunctiva is visible, lagophthalmus 4 mm, fissure palpebral vertical (FPV) 12 mm, margin reflex distance (MRD) 1 = 4 mm, MRD2 = 8 mm, fissure palpebral horizontal (FPH) 30 mm, conjunctival injection. Corneal (macular) scars central-peripherally at 3-6 o'clock. Patient was diagnosed with cicatrical ectropion with left eye corneal scar and ectropion repair was performed with full-thickness skin graft from retroarticular. One week and six weeks after surgery, FPV improved to 10 mm, MRD1 = 4, MRD2 = 6 mm, FPH 30 mm, and lagophthalmos 2 mm became 1 mm.

Discussion : Cicatricial ectropion is usually treated in 3 procedures: release vertical scar traction, horizontal lid tightening, repair anterior lamella can be done with full-thickness skin graft. horizontal lid tightening in this case not carried out because of no laxity.

Conclusion : Scar traction release and repair anterior lamella with full-thickness skin graft from retroauricular was choice in this case because extensive defect and ectropion grade 3. After surgery anatomical structure of the lids and looks better aesthetically.
How to Quickly and Affordably Reduce Corneal Neovascularization
Authors: Surya Atmaja  , Elfa Ali Idrus  , Feti Karfiati  , Patriotika Muslima  , Arief Akhdestira Mustaram  , Angga Fajriansyah
Published: February 2024

Abstract

Introduction : Fine needle diathermy (FND) is one of the treatment modalities for corneal neovascularization (CoNV). Occlusion of the CoNV will reduce vascular leakage, thus preserving visual acuity. This case report presents FND as a treatment for CoNV due to ocular rosacea.

Case Illustration : A 25-year-old volleyball athlete came to Cicendo Eye Hospital after experiencing blurry vision for a week, followed by flushing on the face. A general examination revealed telangiectasia and pustules on the central face (Figure 1). Visual acuity was 0.2 RE. A slit-lamp examination revealed hyperemiain the lid margins, oedema, and superficial-stromal neovascularization on the cornea (Figure 2). The patient was diagnosed with blepharo-kerato-conjunctivitis on RE due to ocular rosacea. The patient then underwent FND (Figure 3). The procedure was performed by using a 10.0-gauge needle inserted in the corneal stroma along the CoNV. The vessels were occluded by conducting monophasic diathermy at a power of 1 mA (Figure 4). On the 5th day, corneal oedema and neovascularization were reduced, and visual acuity improved to 0.4 ph 0.5 (Figure 5).

Discussion : Corneal neovascularization may affect corneal transparency and thus reduce visual acuity. FND is relatively affordable and widely available. Compared to another modality, FND has not been widely performed to treat CoNV. A literature search using PubMed or Google Scholar found few case reports or reviews regarding successful cases of FND.

Conclusion : Fine needle diathermy is a safe and effective treatment for CoNV due to ocular rosacea. Further studies should be conducted to evaluate the safety and long-term efficacy of FND.
CORRELATION BETWEEN COMPLIANCE OF SPECTACLE WEAR AND MYOPIA PROGRESSIVITY RATE IN MEDICAL STUDENTS OF DIPONEGORO UNIVERSITY
Authors: Kingwijati Syahriza Naufal , Wildan Arief , Dharma Andhika Guna , Nugroho Trilaksana
Published: February 2024

Introduction and Objective

Myopia is a refractive error that causes images of distant objects to be focused in front of the retina by the non-accommodating eye. Myopia is one of the most common visual disturbances in the world. It is believed that the use of spectacle can reduce the progressivity rate of myopia. Spectacle can help light fall on the retina and prevent axial elongation of the eye. This theory needs to be investigated further so that it can be used as a reference. This study aimed to know the correlation between compliance of spectacle wear and myopia progressivity rate in medical students of Diponegoro University (UNDIP).

Methods

This research was an observational analytical study with cross-sectional design on 54 subjects ranging from 18 to 22 years old. Data are primary data obtained from questionnaires and objective eye examinations using an autorefractometer. The research was conducted from October to November 2021. Data were analyzed using Spearman Rank test which p<0,05 was considered significant.

Results

The mean of compliance of spectacle wear and myopia progressivity rate in medical students of UNDIP are (1,57±0,108) and (0,259±0,515) dioptres respectively. The correlation between compliance of spectacle wear and myopia progressivity rate are p=0,082 and r=0,239.

Conclusion

There are no correlation between compliance of spectacle wear and myopia progressivity rate in medical students of UNDIP.
BILATERAL SEROUS RETINAL DETACHMENT AS OCULAR MANIFESTATION IN ACUTE LYMPHOBLASTIC LEUKEMIA: A CASE REPORT
Authors: Anthea Casey  , Dian Estu Yulia
Published: February 2024

Introduction : Acute lymphoblastic leukemia (ALL) is known to cause several ocular involvements. However, retinal detachment is a rare complication. This report aims to present unusual ocular manifestations in the form of bilateral serous retinal detachment in a pediatric patient.

Case Illustration : An 11-year-old girl with a diagnosis of relapsed ALL and thrombocytopenia was referred to the Ophthalmology Department due to sudden blurred vision. The patient was undergoing chemotherapy on the third cycle due to the relapse. Visual acuity was 1/300 in both eyes. Fundus examination showed bilateral serous retinal detachment. No treatment in ophthalmology was given due to the unstable condition of this patient.

Discussion : Up to 90% of all leukemia patients have fundus changes during the disease. The presence of unilateral or bilateral serous retinal detachment as a sign of choroidal infiltration may be one of the manifestations of acute leukemia, both as a primary sign and a relapse. Literature has shown that chemotherapy, radiation, and systemic prednisone would improve the visual acuity in these patients. However, in this case, when the patient is unstable and experiencing a series of complications, we decided that life-saving treatment comes first.

Conclusion : The incidence of ocular involvements in ALL could be due to the treatment and the disease itself. Prompt recognition of disease led to early systemic treatment and restoration of visual function. The goal of sight-saving comes second after life-saving treatments.
Treatment of Corneal Perforation Using Periosteal Graft Technique With the Continuation of Penetrating Keratoplasty
Authors: ADRIAN PRATAMA  , Petty Purwanita  , Anang Tribowo
Published: February 2024

Introduction : Corneal perforation occurs due to various conditions and management are based on the underlying cause. Modalities to treat corneal leaks is dependent on the size of corneal defect and include tissue adhesive, conjunctival flap, grafts and transplants. Penetrating Keratoplasty (PK) is effective to treat large corneal defect and to improve visual acuity (VA), but unfortunately PK is usually delayed due to availability.

Case Illustration : A 17-years-old teenager was diagnosed with corneal perforation on his left eye, VA at initial visit was 1/300, positive seidel test, and shallow anterior chamber. Patient immediately underwent periosteal graft with subsequent PK surgery one month later. First until eight days postoperatively, VA improved from 3/60 to 6/30. Ten days after PK, a mechanical trauma caused the transplant to be detached, and VA greatly decreased to 1/300. Patient underwent immediate repair surgery. First day after surgery, VA was light perception. Eight days later, VA increased to 1/60 with concurrent iris prolapse. Iris repair was done immediately and eight days later VA increased to 6/60. At day sixteen, the final VA is 6/30.

Discussion : Periosteal graft was performed to maintain ocular integrity. After waiting for a month, PK was performed to improve vision. This combination therapy was successful proven by VA improvement from 1/300 to 6/30.

Conclusion : Periosteal graft is necessary to maintain ocular integrity while waiting for availability of donor cornea. Penetrating keratoplasty is an appropriate procedure for patients with large corneal leaks. It replaces all corneal structures, and it also improve visual function.
THE RELATIONSHIP BETWEEN DURATION OF GAS EMISSION EXPOSURE AND DRY EYE SYNDROME (DES) ON TAXIBIKE DRIVERS IN CENTRAL JAKARTA
Authors: Muhammad Ferdiansyah  , P. Rahmat Daeli  , Alfoni Parsiska  , Clarissa  , M. Dwi Nugroho
Published: February 2024

Abstract

Introduction & Objectives : Dry eye syndrome (DES) is a breakdown in the natural layer of tears that coats the front of the eye. Air quality in Jakarta indicated to be harmful to human health. The average annual PM 2.5 figure in Central Jakarta recorded 27.6 μg/m3. This figure is far beyond WHO standard that is 10 μg/m3. According to AAO one of the risk factors for dry eyes is exposure/injury to chemicals and the environment (dusty, windy, hot/dry). Therefore duration of traffic related air pollutions exposure may have an effect with the severity of dry eye syndrome on taxibike drivers in Central Jakarta.

Methods : Analytic observation with cross sectional approach. Population was 196 taxibike drivers of Central Jakarta from April-May 2023. Data collection was by means of a questionnaire containing identity,informed consent,duration of exposure,and DES questions accordance with OSDI provisions. The results obtained are then recorded, aggregated, and entered into charts and tables. Hypothesis test used is chi-square.

Results : There were 196 participated in this study. A total of 8 participants(4,1%) with >12hours duration of exposure experienced severe dry eyes, 18 participants(9.2%) experienced moderate, 102 participants(52%) experienced mild dry eyes and the rest was normal(34.6%). According to this, prevalence of DES was more frequent in taxibike drivers who worked 6-12hours more than in <6hours of worked (OR: 1.764) and the severity increased with duration of exposure(p<0.05).

Conclusion : The duration of gas emission exposure has significant correlation with the frequency and severity of DES on taxibike drivers in Central Jakarta.
Bilateral Chronic Papilledema caused by Space Occupying Lesion: A Case Report
Authors: BEATRICE MARIA POLUAN  , STEVANUS PALILIEWU  , ROBBY TUMEWU
Published: February 2024

Abstract

Introduction : Papilledema is edema of optic disc due to raised intracranial pressure (ICP). Papilledema threatens both life and vision, therefore workup for the etiology of raised ICP is needed, including neuroimaging. Intracranial tumors cause increased ICP leads to papilledema. This case report caseof bilateral chronic papilledema as manifestation of space occupying lesion (SOL).

Case Illustration : A 36 years old female presented with blurry black vision on the both eyes since 3 months ago. Complaints were felt suddenly with dominance on the left eye and accompanied with headache. Patient with 12 times history of motorcycle accidents without using helmet in the last 2 years. Funduscopy shows bilateral papilledema. MRI shows orbital within normal limit and solid lobulated mass extra-axial impression in the left posterior parietal region pressing on the left parietooccipital lobe with perifocal edema that obliterates the left lateral ventricle and results in a midline shift to the right. Neurosurgeon had planned for elective craniotomy tumor removal.

Discussion : Increase in the total amount of intracranial tissue by SOL as underlying mechanism of raised ICP. SOL often causes intracranial hemorrhage, which frequently leads to papilledema. High ICP also produces a rise in CSF pressure surrounding the optic nerves leading to axoplasmic flow stasis, causing visual loss. High ICP due to SOL is typically treated surgically.

Conclusion : This case explain that raised ICP caused by SOL leading to manifestation of papilledema.
Management of Post Tumor Resection in Inferolateral Eyelid using Periosteal Flap and Canthoplasty Technique – A Case Report
Authors: CLARA VALENTINA  , Putu Yuliawati  , Ni Made Laksmi Utari
Published: February 2024

Introduction : Eyelid defect repair goals are providing supportive connecting tissue and functional mucosal epithelium. Posterior lamellar reconstruction for tumor resection defect is still challenging. In this case, lower eyelid reconstruction can be accomplished by elevation and rotation of periosteal flap as posterior lamella.

Case Illustration : A 68-years-old male came with inferolateral eyelid mass of Left Eye (LE) that was increasing in last 3 months. On LE examination found solitary cystic cutaneous lesion in inferior palpebra near lateral canthal, sized7x5mm, fixated, regular, and chewy consistency. Anterior of mass has same color as adjacent skin with hyperpigmentation lesion and posterior side was translucent with telangiectasia. He was suspected with LE ductal dd epidermoid cyst.

Discussion : Periosteal flap and canthoplasty is procedure to repair inferolateral eyelid defect that are large to be closed primarily, however it requires adequate lateral canthal skin and tarsal plate. Posterior lamellais restored to create connective tissue framework, proper contour, and vertical canthal height. Tumor was removed and preperiosteal plan inferior to inferior orbital rim was dissected. The anterior lamella then transposed superiorly to make sure it will cover posterior lamellar reconstruction. Periosteal flap from lateral canthal tendon of infraorbital margin was harvested, flap was crossed to form sharp canthal angle and sutured to tarsal edges of lower eyelids as posterior lamella. A week later, LE showed natural contour and good function without eyelid malposition.

Conclusion : Periosteal flap as posterior lamella reconstruction of eyelid defects is effective and efficient to repair eyelid defect due to its simplicity, reliability, and low risk complication.
Epiblepharon Induced Anisometropic Amblyopia : Should We Treat or Observe?
Authors: Syena Damara Riza Gustam  , Ani Ismail
Published: February 2024

Introduction : Previous study reported that epiblepharon strongly associated with astigmatism. Uncorrected refractive errors are considered the most common cause of amblyopia. Amblyopia by pure anisometropia is the one with the best prognosis recovery of visual acuity.

Case Illustration : A children, 9 years old complained of eye discomfort, watery eyes and difficulties in recognizing distant object. After clinical examination and investigations, the patient had visual acuity 5/60 for right eye and 6/18 for left eye was identified as epiblepharon in both eyes with corneal erosion in right eye. The patient underwent repair epiblepharon surgery for right eye and topical antibiotics for corneal erosion. At 2 months after surgery, corneal erosion completely resolved. Best corrected visual acuity 6/21 with spectacle lens S - 1.00 C - 3.00 X 180o positive crowding phenomenon, and 6/6 for left eye with S – 1.00 C - 1.00 X 180o. Topography examination show with-the-rule astigmatism. At 2 month follow up after correction, visual acuity reached 6/6 for both eyes.

Discussion : Epiblepharon induced astigmatism by mechanical force of the eyelid that influences corneal contour. Long term epithelial erosion also contribute to triggers corneal curvature remodelling and induced with-the-rules astigmatism. Diopter differences for astigmatism more than 2.00 D leads to anisometropic amblyopia.

Conclusion : Adequate correction after surgery is proven to recover visual acuity in amblyopia patient caused by epiblepharon
Clinical Feature of Langerhans Cell Histiocytosis of the Orbit : A First Case Series in Indonesia
Authors: ZENDY SAGITA  , NENI ANGGRAINI  , MUTMAINAH
Published: February 2024

Introduction : Langer hans histiocytosis (LCH) is an inexplicable disease characterized by proliferation of Langerhans and intermixed with inflammatory cell, in particular eosinophil, which represents only 1% pediatric orbital tumours. Orbital involvement of LCH is a rare clinical entity as the disease simulate variety of malignancies and present as a diagnostic and management dilemma for ophthalmologist.

Case Illustration : Two cases of toddler presented with unilateral progressive upper eyelid swelling and proptosis for more than a month. Both cases has history of orbital trauma 1 month before swelling was observed. Initial CT scan revealed extraconal mass, with destruction of lateral orbital wall and frontal bone. Both patients had histopathological biopsy confirmed eosinophlic cytoplasm. One patient confirmed immunohistochemistry markers S100 and CD1a which is specific for Langerhans cells. Both patients continue with chemotherapy as definitive treatment.

Discussion : LCH is a wide clinical spectrum which manifestation simulate other pediatric orbital malignancies. Case illustration present unilateral eyelid swelling with history of trauma may resemble other diagnosis unless further work up is performed. This case series exhibits clinical manifestations that may be suggestive of LCH. Considering rapid progression of disease, definitive diagnosis is a mandatory based on histopatological analysis through biopsy surgery.

Conclusion : LCH is rare disease, it should be considered as one of deferential diagnosis in pediatric orbital malignancy with initial presentation acute unilateral eyelid swelling, proptosis, history of trauma, extraconal mass and destruction of bones as radiological features. This might be helpful for early recognition and prompt treatment of disease suggestive of LCH.
Efeito Sexo-Específico da Mutação Termolábil C677T no Gene da Metilenotetrahidrofolato Redutase na Doença Arterial Coronariana Avaliada Angiograficamente em Brasileiros
Authors: Heitor Ghissoni de Carvalho  , Larissa Gonçalves Coutinho  , Amanda Silva Fraga  , Marcelo Góes Alves da Silva
Published: February 2024

Conhecendo-se a importância da hiper-homocisteinemia na ocorrência de DAC, o presente trabalho tem como objetivo resgatar conceitos de um trabalho extremamente relevante publicado na revista Human Biology em 2007 sobre a interação do homozigoto 677T com o sexo como um preditor de DAC, independente de outros fatores de risco clássicos e grupo étnico.
PROBLEMATIKA FAKTOR STUNTING PADA WILAYAH PESISIR (Studi Kebijakan Pada Kabupaten Buton Tengah Tahun 2022)
Authors: Azhari  , Dedihasriadi  , Muis
Published: February 2024

The aim of this research is to determine Problematic Stunting Factors In Coastal Areas through a Policy Study in Central Buton Regency in 2022. This research is qualitative research with a case study approach. Data collection was carried out using interview methods, various document studies and observations. The results of this research show that the lack of coordination between various institutions in the regional TPPS Team, such as BKKBN, Village Government, and Community Health Centers, caused high stunting rates in Central Buton Regency, Southeast Sulawesi in in 2022. Apart from that, the existence of societal myths, inadequate parenting patterns, early marriage and poor sanitation also play a role in increasing stunting rates in the area. Financial constraints also caused many work programs within the TPPS Team to not be realized.
Serpentine spring design technique for high sensitivity MEMS capacitive accelerometer fabricated by gold multi-layer metal technology
Authors: Miyado Kisuke , Tenneti Devi Srujana , Onishi Akira , Machida Katsuyuki , Kurioka Tomoyuki , Chang Tso-Fu Mark , Sone Masato , Miyake Yoshihiro , Ito Hiroyuki
Published: February 2024

This paper describes a design technique for serpentine spring with the edge span beam L/2. In order to improve design accuracy, we investigate the key structure parameters influenced by the fabrication process for MEMS device, comparing finite element analysis (FEA) and analytical models. It is found that the Fedder model as the analytical model is suitable for the spring constant characteristics of FEA with the edge span beam L/2. Further, the thickness and width are found to be the key structure parameters and the dominant factor of variation regarding the serpentine spring. Based on the analysis, we propose a spring design technique. The experimental results show that the variation between the measured data of 4.46 N m−1 and the design value of 4.15 N m−1 was 7.5%, satisfying the target of ±10%. It is confirmed that the proposed technique can establish the serpentine spring for high sensitivity gold proof-mass MEMS accelerometers.
Simulation study of trap-induced noise characteristics in FDSOI MOSFETs
Authors: Xu Jinghan , Fan Mengqi , Sun Zixuan , Liu Fei , Liu Xiaoyan
Published: February 2024

The trap-induced noise characteristics of fully-depleted SOI (FDSOI) MOSFETs with ultra-thin body and buried oxide are essential for high-performance applications. However, accurate noise modeling and traps identification of the device remains challenging. In this work, we investigate the noise characteristics of FDSOI MOSFETs arising from traps in both the gate dielectric (GD) and the buried oxide (BOX). By using TCAD tool, we examine the noise generated by traps at various energy levels and spatial positions in GD and BOX under different biases. The simulation results reveal that traps in GD and BOX exhibit distinctly different behaviors as Vg increases, providing insights for identifying traps from noise measurement results.
Effect of intended shift in propagation direction of cavitation generation position on coagulation position in bubble-enhanced ultrasonic heating
Authors: Kannoto Sota , Yoshizawa Shin
Published: February 2024

High-intensity focused ultrasound (HIFU) is a noninvasive cancer treatment that uses powerful focused ultrasound energy to coagulate tissue. However, due to its small focal region, this treatment is time-consuming. Therefore, we have focused on the heating effect of cavitation bubbles. The safe utilization of bubbles requires that they are consistently generated and maintained in the treatment area. In this study, the effects of the HIFU focal shift in the direction of ultrasound propagation on the bubble and coagulation regions were investigated by high-speed camera and ultrasound imaging. As a result, the appropriate focal shift of pulses that generates the bubbles prevented expansion of bubble regions and generated coagulation regions with good reproducibility near the treatment target.
Magnetic field tuning of photoelectric and photoluminescence effects in BiFe0.9Co0.1O3 thin film
Authors: Huo Guanzhong , Li Jinyan , Su Chao , Xu Hongyu , Chen Guilin , Chen Shuiyuan
Published: February 2024

The reported BiFe0.9Co0.1O3 film presents an interesting magnetic field tunning effect on the photoelectric properties and photoluminescence spectra. The change rate of the photocurrent up to 123.6% was achieved when applying a 400 Oe magnetic field to the film, which is attributed to the spin scattering of photoelectrons in the film. The experimental result of the magnetic field tuning photoluminescence spectra indicates that the magnetic field inhibits the radiative transition of the photogenerated carriers in the thin film and therefore reduces the intensity of photoluminescence. This research provides a basis for the research and application of devices in the field of multifunctional photoelectric materials.
Digital tools as a key element of human resource management technology in the conditions of digital transformation
Authors: Smeshko O. G. , Mordovets V. A. , Vardanyan E. O.
Published: February 2024

Aim. To identify technological features of human resource management (HRM) in the conditions of digital transformation.

Objectives. To describe the main directions of HRM technology transformation in modern conditions; to define the concept of "digital tools"; to systematize the digital tools used in modern conditions; to identify promising directions of using digital tools on the way of digital trans- formation.

Methods. The authors used in the research process the methods of contextual analysis, modeling terms and models, induction and deduction, synthesis and description, applied methods of comparative, system and structural analysis.

Results. The outcome of the digital transformation of business is a progressive process, which in the end will radically affect the functioning of personnel. In this regard, the concept of "digital tools" of HRM is defined, their relationship with HRM technologies is revealed. It is revealed what digital tools are most often used today in Russian companies, whether there is their classification by forms of application and whether digital tools affect the technological process of HRM. The peculiarity of applying HRM tools from the possible set of tools is its scientific substantiation on the one hand and the practice of its application on the other. The basis is the orientation on the solution of a certain problem faced by the company in the current period. In order to get an effective effect, it is necessary to refuse from haphazard ap- plication of tools. A technological process of HRM should be formed, which will be based on a clearly structured sequence of actions that are interchangeable. An important element that should be paid close attention to is the understanding that the new information reality will place increased demands on the competencies of personnel. The article emphasizes that the digital transformation of business should be carried out progressively, taking into account the timely mastering of new digital competencies by employees.

Conclusions. The digital transformation of business taking place today launches new, previously unobserved processes that cover all spheres of functioning of real commercial enterprises. Business can get a new quality both in the aspect of formation of management decisions on an objec- tive basis and in the framework of HRM. In this regard, it is safe to say that we are waiting for a systemic restructuring of the main business processes and, as a consequence, the introduction of new HRM tools, on the basis of which it will be possible to design digital HRM technologies.
Crowdfunding: Nature, essence and conditions for the realization of innovative business projects
Authors: Lapidus L. V. , Polyakova Yu. M. , Tonoyan V. S.
Published: February 2024

Aim. Formation of methodological foundations of crowdfunding, determination of conditions for realization of innovative business projects.Objectives. Clarification of terminology, functions, categories, types and features of stakeholder interaction in the process of realization of crowdfunding campaign; description of the process of realization of innovative business projects with the help of crowdfunding; analysis of foreign and Russian crowdfunding platforms, legislative base to determine the conditions of successful crowdfunding campaign of innovative business project.Methods. The research applied methods of benchmarking, comparative analysis, inductive approach to the formation of the methodological basis of crowdfunding, modeling of the process of implementation of crowdfunding campaign of investment business projects.Results. The methodological foundations of crowdfunding are presented, the functions are described, including the collection of funds, advertising and PR of the product/service produced, scaling of the business, as well as categories, types and features of stakeholder interaction in the process of realization of crowdfunding campaign. The process of realization of an innovative business project on a crowdfunding platform is divided into five stages: MVP of the innovative product, financing of the innovative project, launch of the innovative business project on the crowdfunding digital platform, control over the project realization, launch of the innovative product into production. The analysis of the Russian legislative framework revealed a number of shortcomings in the regulation of investment platforms: lack of clarifications on the regulation of activities with cryptocurrency transactions, the conduct of which is legally permitted; attracting investments is available only to legal entities and private entrepreneurs, which hinders the development of startups and does not provide opportunities for fundraising for the implementation of social projects by individuals.Conclusions. A successful crowdfunding campaign of an innovative business project can be conducted if the conditions and sequence of stages of the process under consideration are met. At the same time, the revision of the legislative base in the field of regulating the activities of investment platforms is of particular importance in the development of this area of the economy.
The concept of increasing the efficiency of financial risk management based on the application of new digital technologies
Authors: Kunin V. A. , Ryskov I. E.
Published: February 2024

Aim. Development of the author’s concept of increasing the efficiency of financial risk management on the basis of application of the technology of creating and using the digital twin of the enterprise.Objectives. To formalize the problems of existing approaches to solving the problems of financial risk management of enterprises of the real sector of economy; to identify trends in the development of digital twins, to formulate the advantages of their practical application and to give the author’s interpretation of the concept of “digital twin of the enterprise”; to build and substantiate a multilayer system of indicators of the digital twin of the enterprise in the context of improving the efficiency of financial risk management; to develop the principles of building a digital twin of the enterprise, focused on solving the problems of financial risk management.Methods. The research was carried out on the basis of system approach, in the process of realization of which the methods of synthesis, logical comparative, factor and graphical analysis, basic provisions of financial risk management and the results obtained in domestic and foreign scientific literature on the problems of realization of approaches and methods of financial risk management were used.Results. The author’s concept of increasing the efficiency of financial risk management based on the application of new technologies for creating digital twins is proposed. In particular, by means of formalizing the problems of existing approaches to solving the problems of financial management, identifying trends in the development of methodology and technologies for creating digital twins, the idea of increasing the efficiency of financial risk management on the basis of creating a digital twin of the enterprise is outlined. The multilayer system of indicators defining the structure of this digital twin is proposed and substantiated, the tasks are defined and the principles of its construction oriented to solving the tasks of financial risk management are developed. The financial kernel of the digital twin of the enterprise is constructed, containing the contours of formation of financial indicators common for different enterprises, determining the achievement of the objectives of financial risk management and its efficiency. The qualitative substantiation of increasing the efficiency of financial risk management with the application of the methodological basis for the creation and use of digital twins proposed in the article is given.Conclusions. Conceptual provisions of creation and use of digital twins for the purposes of financial risk-management, given in the article, create a theoretical and methodological basis for increasing the efficiency of financial risk-management taking into account the use of new digital technologies and can serve as a basis for practical construction of effective systems of financial risk-management at enterprises of the real sector of economy.
Sul testo del finale della Lisistrata e sul "canto tradizionale" di congedo
Authors: Magnelli Enrico
Published: February 2024

Il confronto col finale degli Acarnesi, dei Cavalieri, delle Rane e del Pluto non incoraggia, diversamente da quanto a volte si afferma, a ritenere integro quello della Lisistrata. Nella lacuna deve essere andata perduta non una lunga parte lirica, ma una breve formula di congedo sì.
 
A comparison with the final scenes of Acharnians, Knights, Frogs, and Plutus does not suggest – as some scholars indeed assume – that Lysistrata’s one is complete. Some words must be missing: probably just a brief conclusive statement, not a long lyric sequence.
Matching Critical Analog Circuit Components up to 3rd Order Gradients for All Possible Exact Matching Ratios
Authors: Sekyere Michael , Bruce Isaac , Yang Ruohan , Chen Degang , Mcandrew Colin C , Jin Xiankun , He Chen , Garrity Doug
Published: February 2024

This paper presents a systematic approach to generate layouts for two devices, with an arbitrary integer ratio of device sizes, that cancels up to at least 3 rd order gradient effects. A new analysis leads to mathematical constraints on 1dimensional layouts that meet the required integer ratio and cancel 2 nd-order gradients. From those layouts, we apply reflection and rotation symmetries to generate 2-dimensional layouts that cancel higher-order gradients. Importantly, our procedures can handle ”dummy lanes” to ensure ”routability”. Furthermore, we discuss evaluation metrics that identify which of the multiple gradient canceling layout is best for any fixed rectangular grid and device application.
Some Perspectives on Vibrant Economy of Uttarakhand
Authors: Joshi Prem Lal , Nag Shilpa
Published: February 2024

This article illustrates current economic trends and the development of the Uttarakhand economy using an integrated approach. The information and data were collected from a range of sources, including primary and secondary sources, as well as interviews with particular professions, etc. According to analysis, Uttarakhand's economy is doing quite well despite some clear challenges and problems. Over the past 10 years, the state's GDP and per capita income have more than doubled, and the economy has grown by 8.76% on average. More than 48% of the SGDP comes from the secondary sector. Through an investor summit, the administration is drawing substantial capital investment into the economic areas for which it has now set priorities. Because these industries are essential to economic growth, job creation, and preventing brain drain from the state, they are receiving more attention for development. These are tourism, MSMEs, the IT sector, food processing, agriculture, horticulture, and so on. The article makes a number of recommendations for the state's quick growth in tourism. A number of welfare schemes have been launched, and healthcare facilities are continuously increasing. Women's growth and empowerment are given top importance, and the state has put in place a number of social programs. In Uttarakhand's steep terrain, despite environmental problems and natural disasters, infrastructure and connections are rapidly increasing. The state's youthful, dynamic chief minister is well aware of his goals to turn Uttarakhand into a significant economic powerhouse by prioritizing environmentally friendly economic development and providing work opportunities for young people in order to reverse the state's brain drain. It may be deduced that Uttarakhand has enticing investment opportunities for anyone seeking to capitalize on the unrealized potential for the state's overall development.
Post-Burn Cervical Retraction: 2 Cases and a Survey of the Literature
Authors: Adil Dehhaze , Omar Bouazza , Otmane Taybi , Sara Tita , Issam Diher , Rim Labbaci , Imane Daghouri Nada , Hamza Barij , Mouad Echmili , Aicha Mai , Mimoun Mahioui , Hanae Tazi
Published: February 2024

Burns are still a fairly frequent accident, affecting more children and women in our society. They generally lead to sometimes dramatic functional, aesthetic and psychological after-effects. Treatment in the acute phase, or at a later stage, conditions the patient's image. The neck, however, remains a high-risk area for the development of retractions, due to its anatomy. The skin is thin, the platysma directly subcutaneous, the hypodermis thin, and immobilization difficult. Once the flange has set in, it can be reconstructed using a variety of plastic and reconstructive surgery techniques, in conjunction with physiotherapy. However, the choice of treatment will depend on the quality and quantity of healthy skin tissue available in the neck. Skin grafting gives good results at a distance, when post-operative preventive measures are followed. Local plasty is a simple and effective solution for the treatment of simple localized bridges. Our work is a case study spread over a 2-year period from November 2021 to November 2023, which includes 2 cases of cervical sprains followed up in the plastic and reconstructive surgery and burns department of the Mohammed VI University Hospital in Tangier. Directed wound healing had been the initial treatment in both our patients, with good compliance in patient N2. Moderate and severe cervical sprains (according to Achauer's classification) were found in both our patients. In both patients, the flange had a functional impact, with limited neck extension and deformity of the cervico-chinese angle. Surgical treatment involved skin grafts in the 1st case, and local plasty in the second. Post-operative re-education remains a therapeutic pillar for obtaining satisfactory results.
COST MINIMIZATION ANALYSIS (CMA) TERAPI INHALASI BUDESONIDE-FORMOTEROL VS FLUTIKASON-SALMETEROL PADA PASIEN ASMA DI RSUD SULTAN SURIANSYAH
Authors:   Jurusan Sarjana Farmasi, Fakultas Kesehatan, Universitas Sari Mulia, Melviani Melviani , Andini Maulida Putri
Published: February 2024

Terapi inhalasi kombinasi ICS-LABA menjadi rekomendasi utama dalam penatalaksanaan asma berdasarkan pedoman terbaru tahun 2019 yang di terbitkan oleh Global Intiative for Asthma (GINA). Symbicort (budesonide-formoterol) dan Seretide (flutikason-salmeterol) adalah kombinasi ICS-LABA dalam satu inhaler yang banyak digunakan di Indonesia. Tujuan penelitian ini adalah untuk mengetahui terapi yang paling cost-minimize berdasarkan metode cost minimization analysis (CMA) di antara kedua terapi inhalasi yang terbukti memiliki kesetaraan klinis. Penelitian ini ditinjau dari prespektif rumah sakit sebagai penyedia layanan kesehatan. Pengambilan data sekunder dilakukan secara retrospektif terhadap data rekam medis & catatan biaya pengobatan pasien asma, pada periode waktu Januari-Desember 2022 di Instalasi Rawat Jalan RSUD Sultan Suriansyah Kota Banjarmasin dan diperoleh sebanyak 70 sampel yang sesuai dengan kriteria penelitian. Analisis data dilakukan berdasarkan pendekatan farmakoekonomi dan uji statistik komparasi dengan metode Mann-whitney. Hasil penelitian menunjukkan biaya medis langsung kelompok Seretide (Rp 220.403) lebih rendah daripada kelompok Symbicort (Rp 237.677). Hasil uji statistik komparasi Mann-whitney U test menunjukkan bahwa terdapat perbedaan biaya medis langsung yang bermakna antara kedua terapi inhalasi (p value 0,021 < 0,05). Disimpulkan bahwa terapi inhalasi ICS-LABA menggunakan Seretide adalah terapi yang paling cost-minimize.
An Analysis Of Students’ Problems In Writing Essays
Authors: Rahmi Wahyuni , Sada Clarry , Riyanti Dwi
Published: February 2024

This research aimed to describe the problems sixth-semester English students face in writing essays and determine the factors that cause the problems. This research was designed to be qualitative, with a descriptive study as the methodology. The subject of this researcher was the twenty students in the sixth semester of the English language education study program, faculty of teacher training and education, Universitas Tanjungpura in the academic year 2022/2023, taken as the sample of the research by using the purposive sampling. Document analysis, qualitative surveys, and interviews were used to get the data. Tools of data collection used were documents, open-ended questionnaires, and interviews. The findings revealed that students had problems writing essays, especially with organization, mechanics, grammar, and vocabulary. Besides, it was also found that the factors caused the problems in writing essays were lack of knowledge, loss of motivation and practice, "writer's block," lack of ability to find related information and facts, lack of ability in word choices and vocabulary mastery, and unsupportive environment.
BIOGRAPHISM OF ONOMASTICS BY A.A. PLATONOV
Authors: Ковалев Г.Ф.
Published: February 2024

В статье рассматривается биография А. Платонова как основной источник его словотворчества при создании имен собственных для художественных произведений. Понятие автобиографизм, по мнению автора данной работы, включает, с одной стороны, всю память, накопленную за жизнь автора и лишь отдельными фрагментами, осколочными или цельными, закрепившуюся в его творчестве; с другой стороны, чаще всего – это практически всем известные ситуации, действия или имена. Но в этой двойственности главное – индивидуальное, часто совершенно оригинальное, использование фактов собственной или чужой, но известной автору жизни в своем творчестве. Персонажи А. Платонова автобиографичны и имеют своих прототипов, однако неоднозначный анализ имен собственных свидетельствует о том, что его ономастическая лаборатория до сих пор является загадкой для исследователей. Нами приводятся различные интерпретации ономастических единиц, предлагаемых исследователями творчества А. Платонова. Особым вниманием как лингвистов, так и литераторов пользуются антропоним Дванов и топоним Чевенгур, понимание семантики которых во многом зависит от знания читателем исторического хронотопа, так как писатель вводил в текст реалии не только собственной жизни, но и жизни страны, которые, как известно, сплетались с фактами его биографии. Автором отмечается, что при анализе ономастической лаборатории любого писателя грань между автобиографизмом и биографизмом становится весьма призрачной, несмотря на то что автобиографизмом считается все, что сам автор выносит из собственной биографии в собственное же сочинение, а биографизм – это нечто из биографии писателя, но упомянутое или истолкованное его современниками и близкими.
The spread of Russian disinformation within the Ukrainian information field
Authors: Voitovych Nataliia , Imbirovska-Syvakivska Liliya
Published: February 2024

The objective of this study is to identify and analyse the methods of disinformation utilized by Russia to disseminate information in the Ukrainian information field. The main tasks include defining the concept of disinformation and explaining its societal dangers, characterising Information-Psychological Operations (IPSO) as a component of Russia's disinformation campaign against Ukraine and investigating the most prevalent elements utilised by Russia in the dissemination of disinformation. This study is aimed at the synthesis and combination of methods of monitoring, content analysis, and comparative analysis. The article selects publications that exhibit disinformation targeted at Ukrainian society. Disinformation propagated by Russia is subsequently refuted by either foreign or Ukrainian publications, including the “NotaEnota” organisation. The study reveals that Russian disinformation aims to propagate specific narratives and manipulate mass consciousness. Disinformation involves intentionally creating misleading and manipulative content, often in the form of artificially created fakes. The information field of Ukraine has become the primary battleground for Russia's hybrid warfare tactics, which include disinformation, propaganda, and fakes. To effectively counter these tactics, society needs to develop critical thinking skills and media literacy to discern and evaluate information critically. Future research aims to delve deeper into the methods employed in creating disinformation, their objectives, and potential strategies to prevent or counteract their influence.
Environmental clearance and sustainable development: changing paradigm of environmental constitutionalism in Indian
Authors: Upadhyay Saman Narayan , Singh Milendra
Published: February 2024

Environmental Clearance (EC) to operate in any industry or establishment is firmly accepted across the globe. It is issued after complying with four stages of Environmental Impact Assessment (EIA) namely screening, scoping, public hearing and appraisal. It stipulates the precautionary conditions to operate (CTO) an industry without causing environmental hazards deploying all necessary environmental protection measures. The MoEF&CC issues EC in India, directly or through its regional authorities. In recent decisions, the Supreme Court of India has allowed post-EC to some of the MSMEs that were operating without EC on account of ignorance of the law on the part of the owner as well as the State Pollution Control Board (SPCB). The post-EC has been permitted to remove procedural irregularity by applying the ‘proportionality principle’ on account of MSME’s contribution to the national economy and livelihood to a significant size of the populace. This research paper finds post-EC anathema to the sustainable development principles.
Students’ Perception of Applying Teacher-in-Role during English Learning Process: A Descriptive Study of Middle School Students
Authors: Firdaus Fatimah , Melani Melyann
Published: February 2024

Teacher-in-Role becomes one of the effective methods in the teaching and learning process which indicates the teacher also contributes to playing a role in the classroom to engage the students to take a part a role. This study aimed to describe students’ perception of applying Teacher-in-Role which reflected the purpose of Teacher-in-Role. There were some purposes namely, stabilize the students’ attention, trigger affective and cognitive responses, provide and collect information, try to speak and respond, face challenges or issues and try to handle them, and communicate patterns between teacher and students while Teacher-in-Role. This study was a descriptive study with interviews through focus group discussion as the instrument of this study. There were 10 students in one of the high schools in Padang who participated in this study. The result of this study was a positive perception of students who applied Teacher-in-Role in the classroom. It increased students’ enthusiasm for learning and built a natural atmosphere while they played a role. The students are encouraged trying to take a role due to the unique characters that should be taken. The teachers also became part of them to play the role and also provide them the precise information. However, there was a student to showed the opposite which Teacher-in-Role was ordinary because the students face issues such as nervousness, limited vocabulary, less confidence, and tend to be passive in the classroom. Overall, the students illustrated the positive perception of applying Teacher-in-Role in teaching and learning.

Keywords: Descriptive study; Learning; Perception; and Teacher-in-Role.