bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrasi Nilai-nilai Keislaman dalam Pembelajaran Sains di Madrasah Ibtidaiyah Maâ€™arif 01 KH. Shiddiq Jember
Authors: Rofiâ€™ah Siti Hamidahtur
Published: August 2022

Abstract:
The dichotomy of science between religion and science makes a person only intellectually intelligent, he does not know God, and the role of science is solely for practical purposes. Therefore it is necessary to instill the principles of monotheism in the teaching of general sciences including science, so that religion and science can go hand in hand. The focus of research to be studied is How to integrate Islamic values â€‹â€‹in science learning in Madrasah Ibtidaiyah Ma'arif 01 KH. Shiddiq Jember. The purpose of this study is to describe the integration of Islamic values â€‹â€‹in the study of science in Madrasah Ibtidaiyah Ma'arif 01 KH. Shiddiq Jember. This research uses a qualitative approach to the type of case study. Data collection techniques using passive participation observation, in-depth interviews, and documentation. Data analysis techniques using interactive analysis Miles, Huberman, and Saldana. The results of the study that the method of integrating Islamic values â€‹â€‹in science learning in MIMA 01 KH. Shiddiq Jember by making the Koran and Hadith as a source of knowledge, tracing the verses of the Koran related to Science material. When learning takes place the method used is scientific literacy and discussion to form students who are Ulul Albab.
Keyword: Integration, Islamic Values And Science Learning
Strategi Peningkatan Motorik Kasar Anak Unsur Kekuatan Melalui Permainan Lempar Tangkap Bola Besar Di RA Darussalam
Authors: Wahidah Finadatul , Muniroh Durrotul
Published: August 2022

Anak adalah manusia kecil yang memiliki potensi yang masih harus dikembangkan. Anak memiliki karakterstik yang khas yang tidak sama dengan orang dewasa, anak selalu aktif, antusias dan ingin tahu  terhadap apa yang dilihat, didengar dan dirasakan, mereka seolah-olah tak pernah berhenti bereksprorasi  dan belajar. Anak usia dini merupakan individu yang sedang menjalani suatu proses perkembangan dengan pesat bagi kehidupan selanjutnya.
Motorik kasar adalah gerakan yang membutuhkan koordinasi sebagian besar tubuh sedangkan bermain dapat meningkatkan kemampuan motorik kasar, salah satunya yang  dapat dilakukan dengan bermain lempar tangkap bola besar. Adapun fokus penelitian ini yakni: 1) Bagaimana perencanaan yang dilakukan oleh guru dalam meningkatkan motorik kasar anak unsur kekuatan melalui permainan lempar tangkap bola besar?; dan 2) Bagaimana pelaksanaan peningkatan motorik kasar anak unsur kekuatan melalui permainan lempar tangkap bola besar?
Penelitian ini merupakan penelitian kualitatif yang bertujuan untuk menggambarkan tentang keadaan di tempat penelitian dengan menggunakan rangkaian kata-kata dan kalimat, dengan subyek penelitiannya menggunakan purposive.Metode pengumpulan data menggunakan observasi, wawancara, dan dokumentasi.Analisis data yang digunakan deskriptif kualitatif dengan model interaktif Miles dan Huberman dengan langkah-langkah secara kondensasi data, menyajikan data dan verifikasi/penarikan kesimpulan.Keabsahan data menggunakan triangulasi sumber dan teknik.
Hasil dari penelitian ini adalah: 1) Perencanaan yang dilakukan yakni menentukan pokok bahasan, menyusun Rencana Kegiatan Harian (RPH), menyediakan alat bantu, menjelaskan teknik permainan, menyiapkan lembar evaluasi. 2) Pelaksanaan adalah: a) Gurumemberikan apresiasi dan memotivasi peserta didik serta menjelaskan langkah-langkah permainan; b) Melakakukan pemanasan; c) Anak bisa mengambil, melempar, menangkap dan membawa bola; d) Guru menjelaskan tentang cara bermain lempar tangkap bola besar.
 
Kata Kunci: Strategi, Motorik Kasar, Permainan
Keterampilan 4C Dalam Pembelajaran Untuk Anak Usia Dini
Authors: Maulidah Evi
Published: August 2022

Memberikan pembinaan dan pendidikan pada anak usia dini adalah tepat karena dapat meningkatkan kecerdasannya hingga 80%. Pembinaan yang diberikan tidak hanya berupa hard skill, melainkan juga soft skill. Keterampilan 4C, yaitu Critical thinking, Communication, Collaboration/team building, Creativity and Innovation adalah keterampilan mental (soft skill) yang urgen untuk dikembangkan pada pembelajaran di abad 21 ini. Pada tulisan ini akan digali tentang konsep keterampilan 4C, urgensinya bagi kehidupan di masa mendatang dan pengembangannya dalam pembelajaran anak usia dini.
Kata Kunci : Anak usia Dini, Keterampilan 4C
Peningkatan Motorik Halus Anak Kelompok B Melalui Menggambar Bentuk Di PAUD Nurul Kharomah Baratan Kecamatan Patrang Kabupaten Jember
Authors: Nurhayati Umi , Burhani Siti
Published: August 2022

Kegiatan menggambar bentuk hadir dengan pendekatan tematik dan beranjak dari tema yang menarik minat anak. Menggambar bentk merupakan salah satu bentuk kegiatan berekspresi yang cukup populer bagi anak-anak usia TK. Fokus penelitian ini adalah bagaimana meningkatkan motorik halus anak melalui menggambar bentuk  di PAUD Nurul Kharomah kelompok B Baratan  Kecamatan Patrang Kabupaten Jember Tahun Pelajaran 2018-2019?. Untuk mendiskripsikan pertanyaan tersebut, peneliti menggunakan pendekatan penelitian kualitatif. Hasil penelitian tentang peningkatan motorik halus anak melalui menggambar bentuk  di PAUD Nurul Kharomah kelompok B Baratan  Kecamatan Patrang, yaitu peningkatan motorik halus anak melalui menggambar bentuk  di PAUD Nurul Kharomah kelompok B dengan guru membagikan kertas yang akan digunakan anak, selanjutnya anak-anak mengambil spidol dan krayon. Anak-anak mulai mengerjakan tugas menggambar bentuk.
Keyword: Peningkatan, Motorik Halus Anak, Menggambar Bentuk
Implementasi Permainan Tradisional Lempar Karet Dalam Pembelajaran Matematika Untuk Mengembangkan Perkembangan Aspek Kognitif Anak Usia Dini
Authors: Anysha Pratiwi Yuliska Candra  , Lizza Suzanti
Published: August 2022

Bagi anak usia dini, pembelajaran matematika dirasa sebagai pelajaran yang menyulitkan. Maka dari itu diperlukan media yang dapat membuat anak merasa nyaman menerima pembelajaran tersebut. Salah satu cara yang dapat dilakukan guru maupun orang tua adalah dengan sebuah permainan. Saat ini anak-anak lebih memilih permainan menggunakan gadget, padahal masih banyak permainan-permainan tradisional yang dapat dimainkan serta bermanfaat bagi aspek perkembangan anak. Penelitian ini bertujuan mendapatkan analisis mengenai implementasi permainan tradisional lempar karet dalam pembelajaran matematika anak usia dini. Penelitian ini memanfaatkan desain penelitian kualitatif. Berdasarkan hasil penelitian dapat ditarik kesimpulan bahwa pelaksanaan permainan tradisional lempar karet dianggap cukup efektif digunakan dalam pembelajaran matematika pada anak usia dini

Kata kunci: Anak Usia Dini, Matematika Untuk Anak Usia Dini, Permainan Tradisional Lempar Karet
Implementasi Permainan Tradisional Lore/Engklek Dalam Pembelajaran Matematika Untuk Meningkatkan Perkembangan Kognitif Pada Aud
Authors: Anysha Pratiwi Yuliska Candra  , Lizza Suzanti
Published: August 2022

The purpose of this paper is to find out whether the traditional game of lore/engklek is still in demand among children aged 5-6 years where now children prefer to use their gadgets. And also want to know what mathematics learning is obtained in this lore/engklek traditional game. The research method used in this study used qualitative research methods by observing 4 children and collecting data by observing and observing the results of observations to 4 children who were on Jl.Bambu Kuning V No.23 RT.8 /RW.3, West Cengkareng., Cengkareng District, West Jakarta City, carried out from 09.00 - 10.00 WIB. The results of this observational research on traditional games, all the children were very enthusiastic and happy when they found out that they would play this traditional game from Sungai Nanam Kenagarian, Gumanti Valley District, Solok, West Sumatra. they feel happy to play this lore/engklek traditional game because they have done this game before and really like it when they play this game, not children who refuse to be invited to play this game, but children really want to quickly play this lore/engklek traditional game.

 Keywords: Early childhood, traditional games. Mathematics learning.
AS PRÁTICAS INTEGRATIVAS COMPLEMENTARES EM SAÚDE COMO DISPOSITIVO DE PROMOÇÃO DA SAÚDE NO TRABALHO PARA SERVIDORES PÚBLICOS FEDERAIS DE UMA UNIVERSIDADE DO SUL DO BRASIL
Authors: Rodrigeri Marisete , Kocourek Sheila , Weiss Pinheiro Guilherme Emanuel
Published: August 2022

Verificar o conhecimento e o interesse dos servidores da Universidade Federal da Fronteira Sul (UFFS) sobre Práticas Integrativas e Complementares em Saúde (PICs) e se as percebem como um recurso terapêutico de promoção da saúde. Estudo descritivo e exploratório que utilizou o método misto sequencial explanatório, essa metodologia interliga as abordagens quantitativa e qualitativa.  A análise dos dados quantitativos unidos aos dados qualitativos, os quais formaram o conjunto que revelou três categorias de análise temática. Essas categorias revelam o interesse dos servidores em relação à temática das PICs, sendo que 96% dos servidores se manifestaram favoráveis à implementação das PICs no ambiente de trabalho. Também, indicaram que os servidores consideram as PICs como um instrumento de promoção de saúde, sendo esta a principal razão para sua utilização. Mostrou que os servidores incorporariam as PICs em sua rotina caso tivessem acesso com mais facilidade. Esses resultados permitem concluir que os servidores têm interesse que as PICs sejam implementadas. Tornando-se fundamental, o interesse da gestão na inclusão dessas práticas aos servidores, proporcionar informações, auxiliar na formulação de ações que visem a promoção da saúde, melhoria da qualidade de vida, bem-estar e satisfação dos servidores.
Tarihi Süreçleri Bağlamında Sudan’da Kur’an Eğitimi ve Türkiye’deki Kur’an Kursu Tecrübesi ile Karşılaştırması
Authors: KIZILASLAN İshak
Published: August 2022

Nüzulünden itibaren Kur’an eğitimi Müslümanların üzerinde en çok durdukları konulardan olmuştur. Bu maksatla bütün İslam devletlerinde eğitim kurumları açılmıştır. Bu eğitim kurumları, tarih boyunca farklı İslam idarelerinde, başlangıç seviyesinden kıraat-ı aşerenin farklı rivâyetlerinin tedrisine kadar geniş bir yelpazede Kur’an eğitimi sunan merkezler olarak ortaya çıkmış ve gelişimlerini sağlamışlardır. Bu makalenin konusu, Sudan’da Kur’an eğitiminin tarihi gelişimini ve günümüzdeki durumunu ele almaktır. Coğrafi alanı itibarıyla Afrika’daki İslam ülkelerinin en büyüğü olan Sudan’ın farklı dönemlerde Kur’an eğitiminde yaşadığı gelişmeler bu ülkenin seçilmesinde etkili olmuştur. Tarihinin uzun bir döneminde Osmanlı idaresi altında bulunması da göz önüne alınarak genelde Osmanlı dönemi özelde ise Cumhuriyet sonrası Türkiye’deki Kur’an eğitimi gelişmeleri ile Sudan’daki süreçler karşılaştırılmalı olarak değerlendirmeye tabi tutulmuştur. Ayrıca Osmanlı idaresi sonrası uzun bir dönem sömürgeci olarak Sudan’da bulunmuş olmaları dolayısıyla Batılıların bu ülkedeki Kur’an eğitimine dair yaklaşımları da incelenmiştir. Bütün bu dönemlerde Kur’an eğitimindeki gelişimlerin benzerlik ve farklılıkları arasında bir mukayese yapılması da bu çalışmanın hedefleri arasındadır. Bir diğer amaç ise, İslam toplumlarının oluşumunda ana etkenlerden biri olan Kur’an eğitiminin diğer İslam beldelerindeki tarihi gelişimlerini anlamaya katkı sunmasıdır. Bu hedefe ulaşmak üzere makalede veri toplama ve bunları karşılaştırma yöntemi takip edilmiştir. Yerel araştırmacıların sundukları bilgi ve belgeler yanında özellikle Batılı yazarların kaydettikleri ve yaklaşım tarzları da verilmiştir.
comparative study of the values of some biokinetic variables between two different types of rapid smash hit and their relationship to the accuracy of volleyball performance
Authors: Misjel Nasrallah RaThi , Abdalreda Ahmed Atshan , Jabbar Haidar Shamkhi
Published: August 2022

The importance of the study was manifested in obtaining accurate scientific information, through the biomechanical analysis of the two patterns of rapid crushing beating in front and behind the stomach, to know the strengths and weaknesses in the performance of these two patterns, when measuring the levels of exerted force, and the manifestations of movement that are commensurate with the nature of each pattern, to improve the technical performance of this skill with its patterns. Diverse to the highest levels add to that a statement of the biomechanical properties, and the kinetic manifestations of each style, to advance the requirements of skill performance in a manner consistent with the required motor duty. As for the research problem, through the researcher’s follow-up to many Iraqi Premier League matches in volleyball, and his attendance to some training units for these clubs, note that there are weaknesses in the performance of rapid smash patterns; resulting from the lack of clarity of the biomechanical information and the kinetic features that govern its nature; Which led to a low level of performance in scoring points.
An in vitro study of apical bacterial extrusion after root canal instrumentation using several endodontic file systems
Authors: Doshi Neel Vipul , Saxena Priyank , Shukla Aastha , Sinha Anamika , Saojii Hrishikesh Ashok , Mali Sheetal
Published: August 2022

Aim: In this research, the amount of apical extrusion of bacteria will be measured utilizing root canal instruments, including the K3XF, Protaper Gold, Edge taper Platinum, and Hyflex CM Rotary devices. Materials and Procedures: The saline solution contained sixty recently removed maxillary incisor teeth. After the trenches had been dug, the mash and bacteria were removed and placed in the entry pit to be used. In order to facilitate the gathering of germs, the teeth were attached to a device. Fusobacterium Nucleatum (ATCC 25586) was used to taint and then dry the root trenches for 24 hours. Six meetings made use of various tape systems, including K3XF edge tighten platinum and Hyflex CM turning reports, while the first four made use of hand-written K-records. Group 1 lacked any instrumentation (the control pack). The number of state molding units was tallied after 24 hours of Mueller-Hinton agar testing. The Kruskal-Wallis and Mann-Whitney U tests were used to analyse the data individually. Results: The K3XF file system emitted the fewest germs as compared to the other four rotating systems. Conclusion: Bacteria from intracanal spaces were ejected apically by all instrumentation methods.
effect of Hypnobreastfeeding on the volume of exclusive breastfeeding at the Muara Beliti health center
Authors: Aprilyadi Nadi , Zuraidah Zuraidah , Sutarmi Sutarmi , Juartika Wella , Irawan Ady A. M.
Published: August 2022

Breast milk is the best food for babies, because it contains nutrients that best suit the needs of babies who are in the stage of accelerating growth and development, especially in the first 2 years. Apply Hypnobreastfeeding To Increase The Volume of Breast Milk in Exclusive Breastfeeding In Muara Beliti Health Center musi Rawas Regency in 2021. This study used quasy experiments with two groups of pre and post design approaches. Data collection uses an observation table of the amount of breast milk that is fed. The data is analyzed with a paired wilcoxon test. This study has an effect of hypnobreastfeeding on increasing the volume of breast milk in exclusive breastfeeding. Wilcoxon's test result in the control group was p = 0.000. Conclusion: After this research process. After this research process is done can increase the amount of breast milk and become one way to help mothers in increasing the volume of breast milk.
Evaluation of the circulatory levels of resistin in coronary artery disease with associated co-morbidities
Authors: Kamble Deepak Ramdas , Pandhare Vijay Rajaram , Vidhate Deepali Amarsinh , Vidhate Aarya Amarsinh , Vivek Haritkumar , Jariwala Vidhisha , Thomas Becky Prakash , Thomas James
Published: August 2022

Inflammation is known to be the root cause of the development of coronary artery disease (CAD). Subclinical inflammation is one of the key players in pathophysiology of CAD. An inflammatory response leads to the secretion of various adipokines and cytokines. There are various pro-inflammatory markers which could be used to determine the onset of disease, and one such marker is resistin adipokine. The present study evaluates and compares the circulatory concentration of resistin in CAD patients and controls for the determination of its association with CAD. In this study, 58 CAD patients were enrolled and were further subdivided into four groups as per the associated co-morbidities. Various anthropometric and biochemical parameters were assessed. The circulatory levels of resistin were found to be significantly elevated in CAD patients and their subgroups as compared to controls. We conclude that elevated resistin levels in CAD patients suggest a key role of resistin in the development of CAD. The present study also observed that co-morbidities like type 2 diabetes can act as one of the major factors for the elevated concentration of resistin in the circulation of CAD patients with diabetes.
Reducing dependence on moneylenders with Mawar Emas Program
Authors: Supiandi Supiandi , Pramuja Risky Angga , Azizurrohman Muhammad
Published: August 2022

To develop a community, mosques play a variety of crucial roles, including providing social and economic support. To increase the significance of mosques, a program called Mawar Emas was developed. To help mosque congregations avoid relying on moneylenders, this program offers them training and financial support. The goal of this study is to learn more about the financial plans and programs for Mawar Emas. Through the use of the Atlas.ti program, this study employs a qualitative method. This study discovered that the Mawar Emas program's implementation included contributions from local governments, financial services authorities, bank and non-bank financial organizations, Islamic Economic Community institutions, and mosques. The Mawar Emas program is now creating eight characters. Eight institutions, including banks and non-banks, have expressed interest in sponsoring this program. These include Qardhul Hasan and commercial financing. Only two financial service organizations, nevertheless, distributed money to the general public.
Aulacidae Family as Endoparasitoids of Xylophagous Insects: Of the Order Coleoptera, Hymenoptera and Diptera
Authors: Marchiori Carlos Henrique
Published: August 2022

Regarding the biology of the Aulacidae family, their larvae live under the barks of dying or dead deciduous trees where they are predators or scavengers of the larvae of other insects. Adults, which are rarely captured, are found mainly in wooded areas close to the larval habitat, mainly on trunks and leaves. The aim of this manuscript is to describe insects belonging to the Aulacidae family are parasitoids of Coleoptera, Diptera and Hymenoptera. For this, a bibliographic survey of Aulacidae was carried out from the years 1988 to 2022. Only complete articles published in scientific journals and expanded abstracts presented in national and international scientific events were considered. Additional data was obtained from platforms such as Academia.edu, Frontiers, Qeios, PubMed, Biological Abstract, Publons, Dialnet, World, Wide Science, Springer, RefSeek, Microsoft Academic and Science.
Effects of the Humanized Nursing Model in Obstetric Nursing Based on the Use and Gratification Theory
Authors:   The Obstetrics Department, Shiyan Maternal and Child Health Hospital, Shiyan, China, Luo Lizhen , Liu Jinjin ,   The Obstetrics Department, Shiyan Maternal and Child Health Hospital, Shiyan, China
Published: August 2022

Objective: To explore the application effect of the humanized nursing model in obstetric nursing based on the use and gratification theory. Methods: A total of 148 parturients who were hospitalized in the Obstetrics Department of our hospital from January 2018 to January 2020 were selected as the study subjects. The parturients were then divided into 2 groups, the study group and the control group, based on the order of maternal admission in a ratio of 1:1. Routine obstetric nursing was implemented for patients in the control group. For patients in the study group, an analysis of their needs for humanized care based on the use and gratification theory was performed and a humanized nursing model was constructed. The Edinburgh postnatal depression scale (EPDS), general self-efficacy scale (GSES-C32), and Berlin social support scale (SSS) were used to assess the depression, self-efficacy and social support of patients in the two groups before and after nursing. The pregnancy outcomes and nursing satisfaction of patients in the two groups were also compared. Results: There was no significant difference in the EPDS scores between patients from the two groups before nursing (P>0.05). There was a significant reduction in the EPDS scores of patients from both groups after nursing, with greater reductions seen in patients from the study group than their counterparts in the control group (P<0.05). There was no significant difference in the total efficiency expectation (EE-16), outcome expectation (OE-16) and GSES-C32 scores between patients from the two groups before nursing (P>0.05). After treatment, there was a significant increase in these parameters in patients from both groups, with the increase being more pronounced in the study group than the control group (P<0.05). There was no significant difference in the utilization of subjective support, objective support, social support and total scores between the two groups before nursing (P>0.05). After nursing, there was a significant increase in the utilization of subjective support, objective support, social support and total scores in patients from both groups. The increase was more pronounced in the study group than in the control group (P<0.05). The rates of cesarean deliveries, neonatal asphyxia and postpartum hemorrhage of patients in the study group were lower than those of patients in the control group (P<0.05). The rate of nursing satisfaction in the study group was 97.30%, significantly higher than that of 86.49% seen in the control group (P<0.05). Conclusion: The humanized nursing model in obstetric nursing based on the use and gratification theory is a reliable strategy in obstetric nursing. It can reduce postpartum anxiety and depression, enhance self-efficacy and social support, improve pregnancy outcomes and increase nursing satisfaction.
Sequential and Parallel CNN Structures for the Classification of Lumbar Herniated Disc in MRI
Authors: Mumtaz Mamona , Ahmad Munir , Rahmat Baig Mirza , Ul Haq Naveed
Published: August 2022

The purpose of the present study was to detect the lumbar herniated disc in lumbar spine MRI using Convolutional Neural Network with sequential and parallel models. We performed a CNN classification technique for detecting the normal and herniated disc using sequential (single-input) and parallel (multi-input) models while capturing the effect of dropout ratios and L2 regularizers on the overall accuracy of the model. To overcome the problems of overfitting of CNN model and to enhance the overall performance, we applied data augmentation to our dataset. After evaluating the 87 patients MRI data using sequential and parallel CNN structures, the sequential CNN structure provides higher accuracy of 99.31% (training accuracy) and 96.86% (test accuracy), and when we apply parallel CNN structure, the classification accuracy is also high i.e., 99.52% (training accuracy) and 95.38% (test accuracy). We conclude that the overall sequential and parallel CNN structures provide higher accuracy for the classification of normal or herniated disc in lumbar spine MRI, as compared to when we add dropouts and regularizers in the CNN model. The results demonstrate that our proposed CNN structures significantly outperform the state-of-the-art methods.
EFFECTS OF MORINDA CITRIFOLIA LINN (NONI) AND TAHITIAN NONI® JUICE (TNJ) ON LOCOMOTOR ACTIVITY IN MICE
Authors: Khan Yasmin , Pandi Vijayapandy
Published: August 2022

Noni fruit extract and juice (Morinda citrifolia L., Family: Rubiaceae) had long been known as a medicinal plant in folklore medicine in tropical countries and Pacific islands. To date, the available scientific knowledge was focused on different pharmacological effects. It was claimed to have a beneficial effect on drug addiction by Noni fruit extract and its juice in animal studies. Keeping this in mind we investigated whether the noni fruit extract and noni beverages contained any effect on locomotion in mice using Actimeter (a standard test for locomotor activity). We found that the administration of a single dose of Morinda citrifolia extract (MMC) at varying doses (0.5, 1, 3, and 5 g/kg p.o.) 60 min before the testing and Tahitian noni juice (TNJ) 100% made available as a source of drinking water for a period of 24 hours before the test day produced no significant effect on animal’s locomotion and behavior when compared with the control group. The extract did not exhibit any toxic effects. There was no mortality and change in animal behavior seen. The current results suggest that MMC and TNJ are safe and can be utilized for further neuropharmacological research.
Is Acteoside Effects on Colon Cancer Stem Cells Via Inflamation or Apoptosis?
Authors: FIRAT Fatma , TÜRKOĞLU Canan , OZDAL KURT Feyzan , VATANSEVER Hafize Seda
Published: August 2022

AIM: Colon cancer is one of the main health problems worldwide. Cancer stem cells (CSCs) are referred to as tumor-initiating cells involved in tumor heterogeneity and dormancy. CSCs can cause drug resistance, metastasis, and recurrence of primary and metastatic cancers. The interactions and survival trends of colon cancer stem cells with other cells may be an alternative route for effective treatment. In our study, we aimed to evaluate the effects of asteoside on stem cell properties, apoptotic and inflammatory processes in primary (HCT-116) and metastatic (Colo-741) colon CSCs.
METHERIALS AND METHODS: CSCs were obtained from both types of colon cancer cell lines with the MINIMACS system using the anti-CD133 reagent. Metastatic Colo-741 and non-metastatic HCT-116 CD133+ and CD133- cells were cultured with or without Acteoside for 48 hours. Expressions of Caspase-3, Bcl, Bax, and Fas-L for apoptosis, and IL-1β, TNF-α, IL-6, IL8 and IL-10 for inflammation were analyzed by indirect immunocytochemistry technique by performing H-Score. Changes in cell morphology were examined under an inverted microscope.
RESULTS AND CONCLUSION: It was observed that Oct-4 expression decreased after acteocyte administration in both metastatic and non-metastatic colon cancer cells. In addition, Colo-741 increased the intensity of the Bax/Bcl ratio in both CD133+ and CD133- cells and increased caspase 3 expression. While acteoside did not immunohistochemically affect inflammation in metastatic COLO-741 cells, it contributed to the apoptotic process by changing the Bax/Bcl ratio. When the morphology of the cells was evaluated, it was observed that the number of apoptotic cells increased in COLO-741 CD133+ and CD133- cells.
Comparison of Vitamin D Levels in Patients with Chronic Lymphocytic Thyroiditis and the Normal Population, and Role of Vitamin D on Autoimmunity
Authors: YILDIRIM Serkan
Published: August 2022

Purpose
It is known that vitamin D deficiency has a role in the formation of autoimmune diseases, inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, diabetes, many types of cancer and heart diseases. This study was conducted to demonstrate the role of vitamin D in Hashimoto's thyroiditis.
Methods
In this cross-sectional study, the patients who applied to Izmir Bozyaka Training and Research Hospital endocrinology outpatient clinic between the ages of 16 and 50 were evaluated with ultrasonographically consistent with chronic thyroiditis, serologically antibody positive (anti T, anti M), euthyroid, body mass index (BMI) <30, 40 women with Hashimoto's thyroiditis who did not enter menopause, did not have any other additional disease and did not use chronic medication, and 16-50 women who applied to the internal medicine or endocrinology polyclinics of Izmir Bozyaka Training and Research Hospital 40 healthy female patients with a body mass index (BMI) <30 years and negative for thyroid antibodies were recruited.
Results
When the two groups were compared in terms of age, body mass index, t3, t4, TSH, Anti M, Anti T and vitamin D, no statistically significant difference was found between the two groups. As a result of the Spearman correlation test, no statistically positive or negative correlation was found between vitamin D level and any other parameter (p >0.05).
Conclusion
In conclusion, in this study, it was seen that there may be a relationship between Hashimoto's thyroiditis and vitamin D deficiency. Since vitamin D levels were found to be deficient in the control group, a clear interpretation cannot be made regarding the correlation of Hashimoto's thyroiditis and vitamin D deficiency based on the findings of this study. We hope that our study will be helpful for further studies that will investigate the relationship between autoimmune thyroid diseases and vitamin D deficiency.
The Relationship Between Structural Measurements of the Corpus Callosum and Disability in Patients with Multiple Sclerosis
Authors: DEMİR Aysegul , EREN Fettah , YILMAZ Süeda Ecem , İSLAMOĞLU Necat
Published: August 2022

Abstract
Purpose: The corpus callosum (CC) is the largest commissural pathway connecting both cerebral cortices.
Materials and Methods: Forty MS patients and 40 healthy controls were included in this research, which was planned as a prospective and case-control study. Disability was evaluated with the expanded disability rating scale. The number of attacks, disease duration, and MS disease subtype were determined. CC genu, truncus, splenium, and anterior-posterior diameters were measured in brain magnetic resonance imaging TSE/T1 sagittal sequence, and the corpus callosum index (CCI) was calculated using these measurements. The relationship of all these parameters with each other was examined.
Results: There were 40 patients (29 females, 11 males) with a mean age of 36.47±11.14 years in the study. In the CC morphometric measurements of the patients, the genu (mean±SD) was 11.46±1.60, truncus (median, min-max) 5.29 (4.6-6.52), splenium 11.09±1.82, anterior-posterior diameter 65.20 (63.64-67.22) and CCI was determined as 0.43±0.05 millimeters. The anterior-posterior diameter was smaller in MS patients (p=0.022). A negative correlation was determined between CCI and disease duration, the number of attacks, and EDSS scores in MS patients (p<0.05; r=-0.319; r=-0.316; r=-0.349; respectively). In the severe disability group, CC splenium, AP diameter, and CCI were lower (p=0.007; p=0.020; p=0.046; respectively).
Conclusion: In MS disease, the CC structure is affected, as in many central nervous system regions. The study results revealed that changes in the corpus callosum could be examined as a parameter in evaluating the disease process in MS patients.
Keywords: Multiple sclerosis; corpus callosum; morphometry; disability.
The Impact of Interventions Based on Mishel’s Uncertainty in Illness Theory on Caregivers of Children Diagnosed with Cancer: Randomized Controlled Trial
Authors: ÖZKAN Sevil , TAŞ ARSLAN Fatma
Published: August 2022

Aim: To investigate the effects of nursing interventions based on Mishel’s Uncertainty in Illness Theory (MUIT) on uncertainty, hopelessness, coping and adaptation for care givers of children diagnosed with cancer.

Materials and Methods: The study was randomized controlled experimental design study, which had repeated measures (pretest-posttest-follow up) and parallel group (intervention-control), it included measures of uncertainty (PPUS), hopelessness (BHS), coping and adaptation (CAPS). The study was conducted in January-July 2019 with the caregivers of 46 children diagnosed with cancer who followed in paediatric oncology-haematology clinics. Intervention Group (IG) was given 6 modules education and consultancy according to protocol that was developed based on theory. The CONSORT guideline was performed in the study.

Results: PPUS post-test mean score of IG was lower than CG (p
Erosión eólica en relaves mineros abandonados en zonas urbanas
Authors: Toro Pamela Isabel Valenzuela , González Juan Humberto Palma , Arancibia Gabriel Eduardo Villavicencio
Published: August 2022

La actividad minera ha sido practicada en Chile desde hace varios siglos, inicialmente por parte de los aborígenes, posteriormente los conquistadores y en la actualidad activamente, explotando minerales no metálicos y metálicos, lo que ha contribuido al progreso del país. Sin embargo, esta actividad constituye un potencial riesgo de afectación para personas y el medio ambiente. Los relaves abandonados en zonas urbanas, requieren especial atención, para controlar los negativos efectos que puede provocar la erosión eólica. Esta investigación analiza la situación de los depósitos de relave abandonados en nuestro país, catastrados por el Servicio Nacional de Geología y Minería, discute la problemática de la erosión eólica en depósitos de relave, especialmente cuando estos han quedado insertos en zonas urbanas y las metodologías presentadas en la NCh 3622-2012 Depósitos de relaves - Caracterización del producto supresor de polvo - Evaluación de propiedades de desempeño de los relaves tratados con supresor de polvo, como herramienta para evaluar la situación de un depósito antes y después de ser intervenido. En este contexto, se analizan casos de depósitos de relave emplazados en las ciudades de Andacollo y Copiapó, y las soluciones implementadas para la recuperación de zonas afectadas como espacios urbanos sostenibles, minimizando la erosión en sus superficies. Se concluye que desarrollar estos proyectos contribuye a dar un mejor aprovechamiento al territorio comunal, logrando una mejor calidad de vida de los asentamientos humanos, en concordancia con el desarrollo de actividades económicas y productivas, alineados con la sostenibilidad ambiental.
Güvenlik Güçlerinin Performansında Duygusal Emeğin Etkisi: Kavram Ve Literatür Odaklı Bir İnceleme
Authors: Sağbaş Murat , Yıkılmaz İbrahim
Published: August 2022

İşin ve örgütün gereklerine uygun olarak duyguların yönetilmesi duygusal emek kavramı ile açıklanmaktadır. Özellikle güvenlik gücü personeli açısından hizmet sunduğu mağdur ve suçlu bireyler ve elinde bulunan kamu gücü gözetildiğinde, uygun duygusal emek stratejisinin seçilmesi kritik bir süreçtir. Nitekim duygusal emek örgütsel performans ve çalışanın psikolojik sağlığı üzerinde olumsuz birçok etkiye sahiptir. Bu kapsamda duygusal emeğin güvenlik örgütleri ve personeli üzerindeki etkilerinin incelenmesi amaçlanmıştır. Bu amaca uygun olarak çeşitli indekslerde taranan (Ulakbim, Scopus, Web of Science ve Proquest) yayınlardan ampirik sonuçlar sunan 24 çalışma ayrıntılı bir şekilde ele alınmıştır. Güvenlik güçlerinin etkinliğinin ve performanslarının arttırılmasına ve duygusal emeğin etkilerin azaltılmasına yönelik somut önerilerde bulunulmuştur. Çalışmanın sonuçlarının kaos ve düzen arasındaki ince çizgide önemli bir rol üstlenen güvenlik güçlerinin sosyo-duygusal yeteneklerinin geliştirilmesi, bireysel ve örgütsel performanslarının arttırılmasına yönelik farkındalığı arttırırken, duygusal emek literatürüne önemli katkılarının olacağı değerlendirilmektedir.
SAVUNMA TEDARİK KONUSUNDA YAPILAN ÇALIŞMALARIN BİBLİYOMETRİK ANALİZİ
Authors: Desticioğlu Beste , Asiloğulları Ayan Merve
Published: August 2022

Tedarik zinciri, üretimde ihtiyaç duyulan ham maddelerin temin edilmesi, bu maddelerin son ürüne dönüştürülmesi ve bu ürünlerin müşterilere dağıtımını içeren ağ şeklinde tanımlanabilir. Savunma tedariki ise, tanklar, savaş uçakları, insansız hava araçları, helikopterler, uçaklar, füzeler, elektronik sistemler gibi ulusal savunma için ihtiyaç duyulan ürün ve sistemlerin tasarlanması, test edilmesi, sözleşmeye bağlanması, üretilmesi, kullanıcıya teslim edilmesi, lojistik destek sağlanması, ömür devri sonunda kayıtlarının silinmesi süreci şeklinde tanımlanabilir. Savunma tedariki, gerek ülkelerin ulusal savunması için kritik olduğundan gerekse ürünlerin değişen teknolojiye uyum sağlaması nedeniyle klasik tedarik zinciri yönetiminden farklı stratejiler gerektirmektedir. Literatürde özellikle son yıllarda savunma tedariki konusu dikkat çeken konular arasında yer almaktadır. Bu çalışmada da literatürdeki savunma tedariki konusunda yapılan çalışmalar için bibliyometrik analiz gerçekleştirilmiştir. Yapılan bibliyometrik analiz ile araştırmacıların hangi anahtar kelimelerle arama yapabileceği, hangi yayınları temel kaynak olarak alabileceği, hangi dergilerde bu konuya ait çalışmaların yoğunlaştığı, gelecek çalışmalar için hangi başlıkların önem kazanacağı gibi konularda araştırmacılara yol gösterici bir çalışma olması hedeflenmektedir. Araştırmada Web of Science veri tabanında savunma tedarik konusunda yapılan çalışmalar incelenmiştir. Çalışmaların bibliyometrik analizinin gerçekleştirilmesi için Web of Science’ta yer alan yayın bilgilerinden faydalanılarak VOSViewer programı kullanılarak analizler gerçekleştirilmiştir. Çalışmanın son bölümünde ise elde edilen sonuçlar yorumlanmış ve gelecek çalışmalar için önerilerde bulunulmuştur.
Impact of occupational exposure to petroleum products on coagulation and white blood cell indices of Petrol station attendants in Nnewi metropolis, Nigeria.
Authors: OKEKE CHIZOBA , ONYEKAOMELU ADAOLISA , UMEH OKECHUKWU , IBEH NANCY , CHUKWUMA OLUCHUKWU
Published: August 2022

Petroleum products are complex mixture of hydrocarbon compounds that is easily vaporized during handling. Occupational exposure to petroleum product fumes has become a major public health concern especially in developing countries where adequate protective measures are elusive. These fumes are known to be toxic and can cause abnormal alterations in the functioning of many vital organs. This was a comparative cross-sectional study designed to assess the impact of occupational exposure to petroleum products on the Prothrombin time, activated partial thromboplastin time and white blood cell indices of petrol station attendants (PSAs) in Nnewi metropolis. A total of 100 subjects were recruited comprising 50 petrol station attendants and 50 control subjects. Blood sample was collected and used to assay for the prothrombin time (PT), activated partial thromboplastin time (APTT) and white blood cell parameters. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 21. The Prothrombin time was significantly shorter in the Petrol station attendants than that of the control group (P=0.004), while the activated partial thromboplastin time was significantly longer in the petrol station attendants than the control group (P<0.001). The monocytes count was also significantly higher in petrol station attendants than the controls (P=0.009). Also among the petrol station attendants, the males had significantly longer PT, and APTT values compared to their female counterparts (P=0.008 and 0.006 respectively). Occupational exposure to petroleum products has a detectable impact on coagulation parameters (shorter PT and longer APTT values) which makes it needful that the petrol station workers should be provided with appropriate personal protective equipment to minimize exposure.
Latent profile analysis identified COVID-19 ARDS phenotypes in Thai patients: Research protocol and preliminary report
Authors: Pukiat Namsai , Sutherasan Yuda , Junhasawasdikul Detajin , Suppadungsuk Supawadee , Petchrompo Sanyapong , Theerawit Pongdhep
Published: August 2022

Background: Clinical heterogeneity was observed among COVID-19 patients with acute respiratory distress syndrome (CARDS). The heterogeneity of disease was contributed to different clinical progression, responses to treatment, and mortality.

Objective: We aim to study the phenotype and associated mortality of COVID-19 respiratory failure in Thai patients.

Methods: We conducted a single-center, retrospective observational study. The data were collected in CARDS who received an invasive mechanical ventilator in ICU. Patient-related data were collected at admission before the onset of respiratory failure. The main features include demographics data, SOFA score, laboratory, CXR severity score, treatment during hospitalization, and the following data at the onset of respiratory failure during invasive mechanical ventilator. We also collected patients’ status at 28-day, in-hospital complications, and ventilator-free days at 28-day after intubation. The latent profile analysis was performed to identify distinct phenotypes. After identifying phenotypes, characteristics and clinical outcomes were compared between phenotypes. The primary outcome was the phenotype and associated mortality of COVID-19 respiratory. Secondary outcomes include characteristics of phenotype, ventilator-free days, response to treatment, and complications in each phenotype.

Discussion: This study aims to identify the phenotype of COVID-19SARS-CoV-2 Respiratory Failure in Thai Patients The different phenotypes may be associated with varying responses to treatment and outcomes that the result of this study may be useful for determining treatment and predicted prognosis of COVID-19 SARS-CoV-2 Respiratory Failure In Thai Patients.

Ethics and dissemination: The study protocol was approved by the Institution Review Board of Ramathibodi Hospital, Mahidol University, Thailand (No. MURA2021/740). We plan to disseminate the results in peer-reviewed critical care medicine or pulmonology related journal, conferences nationally and internationally.
Association Between Race/Ethnicity and Total Joint Arthroplasty Utilization in a Universally Insured Population
Authors: Okike Kanu , Chang Richard N. , Royse Kathryn E. , Paxton Elizabeth W. , Navarro Ronald A. , Hinman Adrian D.
Published: August 2022

Introduction:

Previous studies have documented racial and ethnic disparities in total joint arthroplasty (TJA) utilization in the United States. A potential mediator of healthcare disparities is unequal access to care, and studies have suggested that disparities may be ameliorated in systems of universal access. The purpose of this study was to assess whether racial/ethnic disparities in TJA utilization persist in a universally insured population of patients enrolled in a managed healthcare system.

Methods:

This retrospective cohort study used data from a US integrated healthcare system (2015 to 2019). Patients aged 50 years and older with a diagnosis of hip or knee osteoarthritis were included. The outcome of interest was utilization of primary total hip arthroplasty and/or total knee arthroplasty, and the exposure of interest was race/ethnicity. Incidence rate ratios (IRRs) were modeled using multivariable Poisson regression controlling for confounders.

Results:

There were 99,548 patients in the hip analysis and 290,324 in the knee analysis. Overall, 10.2% of the patients were Black, 20.5% were Hispanic, 9.6% were Asian, and 59.7% were White. In the multivariable analysis, utilization of primary total hip arthroplasty was significantly lower for all minority groups including Black (IRR, 0.55, 95% confidence interval [CI], 0.52-0.57, P < 0.0001), Hispanic (IRR, 0.63, 95% CI, 0.60-0.66, P < 0.0001), and Asian (IRR, 0.64, 95% CI, 0.61-0.68, P < 0.0001). Similarly, utilization of primary total knee arthroplasty was significantly lower for all minority groups including Black (IRR, 0.52, 95% CI, 0.49-0.54, P < 0.0001), Hispanic (IRR, 0.72, 95% CI, 0.70-0.75, P < 0.0001), and Asian (IRR, 0.60, 95% CI, 0.57-0.63, P < 0.0001) (all in comparison with White as reference).

Conclusions:

In this study of TJA utilization in a universally insured population of patients enrolled in a managed healthcare system, disparities on the basis of race and ethnicity persisted. Additional research is required to determine the reasons for this finding and to identify interventions which could ameliorate these disparities.
Perception and Preference Towards English Language Learning and Teaching Through Virtual Mode: A Study on English Language Learners and Teachers
Authors: Boruah Deepa Moni
Published: August 2022

The paper intends to discuss English Language teachers' and students' perceptions and preferences toward English Language Teaching and Learning through online or virtual classes. The COVID 19 outbreak and the nationwide lockdown created a new set of environments for all. All educational institutions were closed down to prevent the widespread of the virus as a result the teaching and learning activities were disrupted extensively. All sorts of activities, including teaching and learning, were being carried out through online mode. Traditional classroom teachings shifted to online classroom teaching in order to continue with teaching and learning practices. The online mode of teaching became an effective strategy to continue the teaching and learning process without any interruption. The closure of educational institutions affected a large number of students. The abrupt change in teaching and learning methods impacted both the teachers as well as students. The main purpose of the study was to examine the perception and preferences of learners and teachers towards online learning and teaching. The study adopted the questionnaire method, and the data were collected from undergraduate students (Currently in B.A Third Semester) of Indira Gandhi National Tribal University, Madhya Pradesh by sending a questionnaire to participants' email ids. The English language teachers and students were selected for the present study. English language course is taught at this university as a compulsory subject for first-semester undergraduate students. Two questionnaires, one for the teachers' group and another for the students' group, were prepared to know the opinion of both the participant groups. The study reveals that students are more satisfied with face-to-face teaching than the online mode. All learners believe that learning and speaking English is an advantage, but they prefer classroom teaching over online. Similarly, the teachers’ group also showed their preferences for offline teaching over online teaching. The present paper elaborates on the findings of the present study.
ЦИТОМОРФОЛОГИЧЕСКИЕ ОСОБЕННОСТИ ТЕРАТОЗООСПЕРМИИ ПРИ УРОГЕНИТАЛЬНОЙ ХЛАМИДИЙНОЙ ИНФЕКЦИИ
Authors: Апсалямов Валий Хамитович , Барышев Борис Борисович , Ажкен Бахтияр Талғатұлы
Published: August 2022

Изучение причин и механизмов развития мужских бесплодных состояний, а также необходимость коррекции гипофертильности у мужчин в настоящее время полностью сохраняет свою актуальность в связи с высокой частотой бесплодных браков и неблагоприятной демографической ситуацией во многих регионах мира.Цель: исследовать особенности цитоморфологии и патогенеза тератозооспермии, индуцированной урогенитальной хламидийной инфекцией у бесплодных мужчин.Материалы и методы. Дата исследования: 08.2021-04.22. Дизайн исследования: поперечное исследование. Цитоморфологическим, иммуноморфологическим и ультрамикроскопическим методами изучена семенная жидкость 299 пациентов в возрасте от 21 до 57 лет с урогенитальной хламидийной инфекцией, обратившихся для обследования по поводу бесплодия в браке более 12 месяцев. Результаты исследования. У подавляющего большинства обследованных бесплодных пациентов с урогенитальной хламидийной инфекцией были обнаружены патологические отклонения показателей эякулята, включающие астенозооспермию и тератозооспермию на фоне выраженных признаков нейтофильно-мононуклеарной воспалительной реакции. Цитологической особенностью нарушений морфологии половых клеток явилось накопление в семенной жидкости тератоформ спермиев с избыточной резидуальной цитоплазмой, содержащей микроколонии-включения патогена, обнаруживаемые светомикроскопическим, иммуноморфологическим и электронномикроскопическим методами. Специфичное этиотропное и патогенетическое лечение приводит к постепенному снижению количества клеток с включениями в эякуляте и восстановлению фертильных характеристик семенной жидкости. Зключение. В избыточной резидуальной цитоплазме тератоформ сперматозоидов при мужских бесплодных состояниях, ассоциированных с урогенитальной хламидийной инфекцией, цитоморфологическими, иммуноморфологическими и ультрамикроскопическими методами обнаруживаются включения патогена. Обсуждается значение внутриклеточного присутствия возбудителя в патогенезе тератозооспермии.