bluuebunny/crossref_metadata_2025 huggingface dataset:
Long‐term follow‐up of two siblings with adult‐onset neuronal ceroid lipofuscinosis, Kufs type A
Authors: Özkara Çiğdem , Gündüz Ayşegül , Coşkun Tülin , Alpaslan Bengi Gül , Zeydan Burcu , Delil Şakir , Muona Mikko , Lehesjoki Anna‐Elina , Kızıltan Meral E.
Published: August 2019

Aim. Reports on the clinical presentation of adult‐onset neuronal ceroid lipofuscinoses (NCL) are scarce compared to infantile‐ and childhood‐onset forms. Here, we aimed to present detailed temporal evolution of clinical and electrophysiological features of two siblings with adult‐onset NCL and homozygous mutation in the CLN6 gene.

Methods. We retrospectively analysed medical records and electrophysiological data in order to delineate evolution of clinical and electrophysiological findings. Electrophysiological studies included routine EEG and video‐EEG, as well as polymyographic analysis of myoclonus and brainstem reflex studies.

Results. Both patients had seizures and cerebellar signs. Despite the slow progression of ataxia, they developed no mental deterioration, but had severe obsessive compulsive disorder and depression. EEG revealed frequent generalized spikes, polyspikes, and waves, prominent on awakening and during photic stimulation without significant change throughout the clinical course. Abnormalities concerning the blink reflex, auditory startle response, and startle response to somatosensory inputs manifested within four years. The patients underwent transient and mild improvement with valproate, whereas ataxia and seizures were dramatically ameliorated following high‐dose piracetam.

Conclusions. Patients with adult‐onset NCL may present with slowly progressive ataxia, persistent photosensitivity, and seizures without dementia or extrapyramidal findings. Brainstem abnormalities become more evident with time, in line with ataxia. Piracetam is effective for both seizures and ataxia.
Stereotactic bilateral transfrontal minimal radiofrequency thermocoagulation of the amygdalohippocampal complex for bilateral medial temporal lobe epilepsy: a retrospective study of 12 patients
Authors: Zhao Quanjun , Shi Tiejun , Cui Shaojie , Wu Zhaohui , Wang Wei , Jia Yunfeng , Tian Zengmin , Wang Fuli , Yin Feng , Zhao Hulin , Xiao Xia , Wang Haiying , Cai Changlan , Luo Huimin
Published: August 2019

Background. Some patients with temporal lobe epilepsy have bilateral discharges and a few have bilateral medial temporal sclerosis. Stereotactic bilateral radiofrequency thermocoagulation (RFTC) of the amygdalohippocampal complex can terminate seizures or reduce seizure severity in patients with bilateral medial temporal lobe epilepsy (BMTLE).

Aim. To explore the safety and efficacy of bilateral transfrontal minimal RFTC of the amygdalohippocampal complex for the treatment of BMTLE.

Methods. A total of 12 BMTLE patients were treated with bilateral transfrontal minimal RFTC of the amygdalohippocampal complex under limited coagulations. The volumes of coagulated lesions were less than 0.6 cm3 Clinical outcomes were evaluated using Engel's classification, the Liverpool Seizure Severity Scale (LSSS) 2.0, Wechsler Adult Intelligence Scale‐Revised (WAIS‐R), and Wechsler Memory Scale‐Revised (WMS‐R). Quality of life (QOL) was evaluated using the 36‐item Short Form Health Survey (SF‐36).

Results. Of the 12 patients, five (42%) were assessed as Engel Class I during 12–62 months of follow‐up. LSSS scores declined sharply compared with the baseline of patients not in the seizure‐free category. Functions of memory and intelligence declined transiently without statistical significance (p>0.05) immediately after surgery, but improved significantly (p<0.05) six months later. The qualities of life improved except vitality.

Conclusion. Bilateral transfrontal minimal RFTC of the amygdalohippocampal complex may terminate seizures or reduce seizure severity in patients with BMTLE. Under limited coagulations, neuropsychological function was not affected but improved along with seizure control.
Sensitive quantitative detection of somatic mosaic mutation in “double cortex” syndrome
Authors: Damiano John A. , Do Hongdo , Ozturk Ezgi , Burgess Rosemary , Kalnins Renate , Jones Nigel C. , Dobrovic Alexander , Berkovic Samuel F. , Hildebrand Michael S.
Published: August 2019

Aims. Somatic mutation of the lissencephaly‐1 gene is a cause of subcortical band heterotopia (“double cortex”). The severity of the phenotype depends on the level of mutation in brain tissue. Detecting and quantifying low‐level somatic mosaic mutations is challenging. Here, we utilized droplet digital PCR, a sensitive method to detect low‐level mutation.

Methods. Droplet digital PCR was used in concert with classic genotyping techniques (SNaPshot assays and pyrosequencing) to detect and characterize the tissue mosaicism of a somatic mutation (LIS1 c.190A>T; p.K64X) in a patient with posterior bilateral SBH and refractory epilepsy.

Results. The high sensitivity of droplet digital PCR and the ability to target individual DNA molecules allowed us to detect the mutation at low level in the brain, despite the low quality of the DNA sample derived from formalin‐fixed paraffin‐embedded tissue. This low mutation frequency in the brain was consistent with the relatively subtle malformation resolved by magnetic resonance imaging. The presence of the mutation in other tissues from the patient permitted us to predict the timing of mutagenesis.

Conclusion. This sensitive methodology will have utility for a variety of other brain malformation syndromes associated with epilepsy for which historical pathological specimens are available and specific somatic mosaic mutations are predicted.
Hemimegalencephaly with Bannayan‐Riley‐Ruvalcaba syndrome
Authors: Ghusayni Ryan , Sachdev Monisha , Gallentine William , Mikati Mohamad A , McDonald Marie T
Published: August 2019

Hemimegalencephaly is known to occur in Proteus syndrome, but has not been reported, to our knowledge, in the other PTEN mutation‐related syndrome of Bannayan‐Riley‐Ruvalcaba. Here, we report a patient with Bannayan‐Riley‐Ruvalcaba syndrome who also had hemimegalencephaly and in whom the hemimegalencephaly was evident well before presentation of the characteristic manifestations of Bannayan‐Riley‐Ruvalcaba syndrome. An 11‐year‐old boy developed drug‐resistant focal seizures on the fifth day of life. MRI revealed left hemimegalencephaly. He later showed macrocephaly, developmental delay, athetotic quadriplegic cerebral palsy, and neuromuscular scoliosis. Freckling of the penis, which is characteristic of Bannayan‐Riley‐Ruvalcaba syndrome, was not present at birth but was observed at 9 years of age. Gene analysis revealed a c.510 T>G PTEN mutation. This patient and his other affected family members, his father and two siblings, were started on the tumour screening procedures recommended for patients with PTEN mutations. This case highlights the importance of early screening for PTEN mutations in cases of hemimegalencephaly not otherwise explained by another disorder, even in the absence of signs of Proteus syndrome or the full manifestations of Bannayan‐Riley Ruvalcaba syndrome.
High‐level visual manifestations of epileptic seizures originating from the medial parietal cortex
Authors: Pendekanti Shrita , Baek Sori , Kilinc Yagmur Basak , Parvizi Josef
Published: August 2019

We describe the case of a patient with well‐localized focal seizures originating from the medial parietal cortex. Seizures originated from area 7m, and findings revealed clear visuospatial semiological signs that may be used clinically to help diagnose similar cases of seizures in non‐lesional patients.
Stimulation‐induced ictal vocalisation of left frontal lobe origin
Authors: Baysal‐Kirac Leyla , Hartl Elisabeth , Vollmar Christian , Ernst Katharina , Lohr Hannah , Noachtar Soheyl
Published: August 2019

Pure ictal non‐speech vocalisation occurs in frontal and temporal lobe epilepsies. Electrical stimulation of supplementary motor areas is reported to evoke vocalisation in selected patients. Here, we report a patient with focal epilepsy of the left anterior insula who had isolated monotonous vocalisation elicited by electrical stimulation of the left superior frontal gyrus. Quantitative analysis of audio signals was performed and compared with a former patient with left frontal lobe epilepsy who had pure ictal vocalisation. Both patients showed a comparable reduction in frequency variation indicating a monotonous voice. [Published with video sequences onwww.epilepticdisorders.com]
Epilepsy for primary health care: a cost‐effective Latin American E‐learning initiative
Authors: Carrizosa Jaime , Braga Patricia , Albuquerque Marly , Bogacz Alicia , Burneo Jorge , Coan Ana C. , Contreras Guilca , Guilhoto Laura , Izquierdo Álvaro , Ladino Lady , Lin Katia , Manreza Maria L. , Morales Lilia , Ríos Loreto , Solarte Rodrigo , Valente Kette , Venegas Viviana , Uscátegui‐Daccarett Angélica , Yacubian Elza M. ,   on behalf of the Working Group EVELA (Epilepsy Virtual Education in Latin America), and the ILAE Education Commission
Published: August 2019

Aims. A lack of neurologists in Latin America forces primary health care providers to manage epilepsy. With the main goal of improving diagnostic and therapeutic management of patients with epilepsy through training of physicians in the primary health care level, the International League Against Epilepsy Education Commission (2013–2017) created a low‐cost, regional, virtual course.

Methods. The course, set‐up in Moodle platform, was structured in eight modules, each lasting for a week. Teaching was based on written didactic material, videos, and interactive discussions, both in Spanish and Portuguese. Topics included epidemiology, diagnosis, classification, treatment, prognosis, social issues, and epilepsy policies. Each course was limited to 50 participants and priority was given to general practitioners. Certification was given to those approving the final examination.

Results. Since 2015, five courses have been developed, involving 143 participants from 17 countries and 21 tutors. Of the participants, 61% worked in primary health care services. A total of 129 participants (90%) completed the course, and 110 submitted the final examination with an approval rate of 95%. From 85 participants completing the course evaluation, 98% would recommend the course to other colleagues, and 99% showed interest in taking other similar courses. High self‐confidence for the management of patients with epilepsy increased from 21% at baseline to 73% after the course.

Conclusions. The online course on epilepsy for primary care physicians in Latin America was shown to be a cost‐effective course, with good retention and excellent approval rates. Our current challenges include periodic updating, complete self‐sustainability, and exploring different strategies to reach our target audience more effectively.
Rasmussen syndrome: an atypical presentation in ten patients
Authors: Caraballo Roberto H. , Valenzuela Gabriela Reyes , Pociecha Juan , Princich Juan P. , Gutierrez Robinson , Beltran Lucas , Lubieniecki Fabiana , Bartuluchi Marcelo
Published: August 2019

Aim. The aim of this study was to analyse the electroclinical and imaging findings and outcome of patients with Rasmussen syndrome (RS) with atypical manifestations.

Methods. We conducted a retrospective, descriptive study of 10 of 44 consecutive patients with RS with atypical features, followed between 1999 and 2017.

Results. Six patients were boys and four were girls. The mean and median ages at onset of the seizures were 8.8 and 6.5 years, respectively (range: 4.6‐13 years). All of the patients except one had seizures. Eight patients (80%) had epilepsia partialis continua that started at a mean age of 7.5 years (range: 7–15 years). In our series, hemiparesis without seizures was the first manifestation in three patients, one of whom had dual pathology. In two patients, the first manifestation was dyskinetic movements, followed by delayed‐onset seizures associated with unilateral caudate atrophy. Two patients had a focal lesion mimicking focal cortical dysplasia as the first MRI abnormality; one of these two patients had epileptic spasms in clusters. Bilateral cerebral hemisphere involvement was observed in three patients during the course of the disease. Six of eight patients responded well to surgical treatment.

Conclusions. Progressive hemiparesis alone or with delayed‐onset seizures, dyskinetic movements associated with seizures, a focal lesion mimicking focal cortical dysplasia, and bilateral brain involvement were the atypical features recognized. Our series of patients responded well to surgery. Clinical, video‐EEG, and neuroradiological follow‐up is important for early confirmation of RS in order to initiate adequate management of the condition.
INFORMATION COMPONENT OF THE HUMANITARIAN DEVELOPMENT STRATEGIES OF THE ASIAN AND AFRICAN COUNTRIES
Authors: Kuchmii O.
Published: August 2019

In the context of information development, new opportunities have emerged to solve humanitarian issues by supporting programs for the modernization of developing countries, based on the widespread achievements of science and technology. It is noted in the article that the emergence of new information and communication technologies, bio-and nanotechnologies, their widespread introduction into all spheres of society's life made it possible not only to improve the sphere of information and communication, but also acted as a significant factor in the strengthening of integration and cooperation in various spheres and at different levels of international co-operation. Increasing scale of new technologies using helps to overcome both information asymmetry and the asymmetry of the socio-economic and humanitarian development of the world. The article explored modern approaches to the use of technology for the socio-economic and humanitarian development of some countries in Asia and Africa. The example of the functioning of modern platforms proved that the introduction of «Aadhaar» system helps the Indian government to ensure the integration of socially disadvantaged groups and to overcome informational and socio-economic asymmetries in the country. The emergence of the digital payment platform M-Pesa enables the modernization of payment systems and encourages the development of small business not only in Kenya, but also in other countries of Africa. The functioning of e-commerce platform «Taobao» ensures the modernization and development of the backward regions of China with the traditional economic and social order through the introduction of e-commerce. The article showed that the obvious advantages of the introduction of modern information networks and technologies are expanding the scope of trade, facilitating entrance of small and medium businesses, increasing the efficiency and productivity in almost all sectors of the economy, and creating new jobs. Thus it has been proved that the positive experience of using new technologies in the countries of Africa and Asia can be used to address socio-economic and humanitarian issues in many countries and regions of the world.
La terminología del deporte en los diccionarios generales del español
Authors: Nomdedeu Rull Antoni
Published: August 2019

La terminología del deporte en los diccionarios generales del español.
La elaboración del Diccionario de locuciones verbales para la enseñanza del español
Authors: Penadés Martínez Inmaculada
Published: August 2019

La elaboración del Diccionario de locuciones verbales para la enseñanza del español.
Skill of donning surgical gloves amongst residents: a neglected skill
Authors: Kasula Jayasree , Yerroju Kodandapani
Published: August 2019

Background: Sepsis is a preventable cause of morbidity and mortality. Sepsis causes approximately 1 million new-born deaths annually. The global prevalence of maternal sepsis is 4.4% causing more than 5.7 million cases and one tenth of maternal deaths annually. Skin preparation, shaving and wound closure were some factors involved in surgical site infections. But the technique of wearing gloves in a sterile way has not received enough attention. Hence this cross sectional observational study was undertaken to assess the awareness and proficiency in this technique among the residents.Methods: 104 post graduate students from the departments of General Surgery, Obstetrics and Gynaecology, Paediatrics and Anaesthesiology from two medical colleges were administered a questionnaire and also were observed one at a time with a checklist in an OSCE station. Study was conducted in several sessions over a period of 2 months.Results: None of them were formally taught this technique. 36 (34.56%) were informally taught by seniors. 7 (6.72%) tore the glove while wearing. 39 (37.44%) put two fingers in one finger space. 42 (40.32%) touched bare skin with gloved hands while wearing. 54 (51.84%) touched bare skin with used surface of the glove while removing.Conclusions: Awareness about technique and skill of donning sterile gloves among residents of various specialities are not satisfactory. It is recommended to teach this skill as soon as the students enter medical school in a strict and formal way and monitor their proficiency throughout their training period.
Clinical and radiological evaluation of minimally invasive intramedullary fixation by titanium elastic nails in paediatric long bone fractures of lower limb: a prospective study
Authors: Sandeep A. , Jain Jayant
Published: August 2019

Background: Elastic stable intramedullary nailing for the treatment of paediatric femur and tibial diaphyseal fractures was introduced by Prevot and colleagues in 1979. It follows three-point fixation principle that provides internal support in presence of cortical contact and an intact soft-tissue envelope. This technique has many advantages, including better reduction, dynamic axial stabilization, shorter hospitalization with early rehabilitation and low complication rate.

Methods: This is a prospective observational study done at Kauvery Medical Centre, Trichy between May 2017 to May 2018 consisting of 39 children between age 5 to 16 years with diaphyseal fractures of femur and tibia. The fractures were treated by closed reduction and internal fixation with titanium elastic intramedullary nailing. The patients were evaluated clinically and radiologically and followed for an average of 6 months. Outcome was assessed using transcutaneous electrical nerve stimulation (TENS) scoring system used by Flynn et al.

Results: Our series consisted of 39 patients (22 cases with fracture shaft of femur and 17 cases with fracture shaft of tibia), 33 males and only 6 females. Average time for radiological union was 9.89 weeks. All patients had full range of hip and ankle motion and 2 (5.1%) patients had mild restriction in knee flexion at 12 weeks.

Conclusions: Elastic stable intramedullary nailing is an ideal method for treatment of paediatric femoral and tibial diaphyseal fractures due to lower complication rate and good functional outcome in comparison to other methods of treatment.
POLÍTICAS PÚBLICAS E DESENVOLVIMENTO REGIONAL: A INCLUSÃO DA PESSOA COM DEFICIÊNCIA NO MERCADO DE TRABALHO
Authors: Carvalho Maria Alcenir de , Gumbowsky Argos
Published: August 2019

O objetivo da pesquisa foi verificar a efetividade das políticas públicas, enquanto instrumentos para o desenvolvimento regional, relativos à inclusão do deficiente no mercado de trabalho em instituições públicas e privadas nos municípios do Planalto Norte Catarinense. O presente trabalho é caracterizado como pesquisa descritiva, qualitativa com abordagem quantitativa, apoiada em estudo de campo e bibliográfica. Participaram como sujeitos da pesquisa trinta e seis representantes de organizações públicas e privadas dos municípios de Bela Vista do Toldo, Canoinhas, Irineópolis, Major Vieira, Porto União e Três Barras. Os resultados possibilitaram identificar a necessidade de maior preparo de todos os órgãos públicos e privados, bem como das famílias e das próprias pessoas com deficiência, no que tange a inclusão destas no mercado de trabalho. A inclusão é uma tarefa interativa entre os segmentos sociais com probabilidade de sucesso e soluções se todos os segmentos se comprometerem com ações específicas. E ainda, a importância de um conhecimento específico e de preparo educacional com ações pedagógicas mais condizentes com a perspectiva de inclusão e não de segregação.
OPERACIONALIDADE DAS POLÍTICAS PÚBLICAS SOBRE DROGAS NO PLANALTO NORTE CATARINENSE
Authors: Fuchs Giselle Caroline , Milani Maria Luiza
Published: August 2019

A população do Planalto Norte Catarinense tem na sua história o uso de drogas como uma forma de lidar com as dificuldades do cotidiano, o mesmo aconteceu no mundo todo, uma vez que 5% da população mundial adulta usa alguma droga e com isso estima-se um gasto anual da 7% do PIB de um país para tratar as consequências do uso de drogas. Este artigo objetiva analisar a operacionalidade das politicas públicas e as implicações para saúde pública que o uso de drogas acarreta no Planalto Norte Catarinense. A pesquisa foi de natureza básica, quantitativa e qualitativa, como público alvo os Secretários Municipais de Saúde, gestores dos CAPS e das Comunidades Terapêuticas nos municípios de Canoinhas, Mafra e Porto União. O instrumento foi questionário fechado enviado pelo Google Forms. Com o desenvolvimento da pesquisa foi possível perceber a complexidade do tema e que a sociedade atual incentiva a exclusão do usuário de droga, estigmatizando-o e dificultando o processo de recuperação. Com isso é necessário repensar as crenças e a cultura envolta ao uso de drogas, buscando incluir o usuário nas decisões sobre o tratamento e no desenvolvimento de novas políticas públicas.
Assessment of Soil Phytotoxicity under the Conditions of Technogenic Impact of Enterprises of the Mining and Metallurgical Complex of the Republic of Bashkortostan
Authors: Seregina Yu.Yu. , Semenova I.N. , Suyundukov Ya.T. , Khasanova R.F. , Kuzhina G.Sh. , Rafikova Yu.S.
Published: August 2019

The soil contamination with heavy metals (HM) Cu, Zn, Fe, Mn, Cd and Pb was studied in the zone of influence of the Beloretsk Metallurgical Plant and the Sibay Beneficiating Plant (Republic of Bashkortostan). The direct dependence of phytotoxicity of soils on the content of HM in it at their relatively high concentrations has been established.
On Entering the Field: Notes from a Neophyte Researcher
Authors: Torelli Julian
Published: August 2019

Qualitative field research can capture the life worlds and definitions of the situation of informants often not reported in quantitative studies. Post hoc reflections of how more seasoned researchers de­fine, assess, and interpret the process of entering the field and the interview dynamic between the researcher’s subjectivity and the subjectivity of informants are widespread in the qualitative research literature. However, seldom are the personal stories and reflections of neophyte researchers voiced in published accounts. This article accounts for my experiences in researching the “dirty work” of front­line caseworkers and the importance of practicing empathy while managing a boundary. I emphasize the practical sense-making challenges of managing a delicate balance between under and over rapport in researching homeless shelter caseworkers as an occupational group. My experiences underscore the challenging dynamics of maintaining a professionally oriented research-role, as well as the crucial importance of boundary work and distancing as practical strategies to qualitative interviewing.
Botrytis cinerea causante del moho gris en frutos de zarzamora en México
Authors: Terrones-Salgado José , Nieto-Angel Daniel , Nava-Díaz Cristian , Téliz-Ortiz Daniel , García-Velasco Rómulo , Vallejo-Pérez Moisés Roberto , Sánchez-García Prometeo
Published: August 2019

La zarzamora (Rubus sp.) es una frutilla atacada por el género Botrytis. En México se desconoce que especies están involucradas con el síntoma de moho gris. El objetivo de este estudio fue identificar las especies de Botrytis asociadas a zarzamora. En noviembre-diciembre de 2016, se realizaron muestreos en 17 áreas productoras de zarzamora en México. Se colectaron frutillas con síntomas de moho gris, de las cuales se aislaron y purificaron los aislamientos. Con la técnica de cultivo monospórico, se obtuvieron 211 aislamientos, los cuales formaron 21 grupos basado en un agrupamiento por similitud de las características morfológicas, patogénicas y culturales. De cada grupo se eligió un aislamiento y se identificó molecularmente. El ADN se extrajo con el método de Phosphatasa Alcalina (AP), posteriormente se realizó la reacción en cadena de la polimerasa (PCR) de la región del espacio transcrito interno. (ITS) utilizando los iniciadores ITS1 e ITS4. El producto de amplificación se secuenció en ambas direcciones con el método de Sanger. Se identificaron diferencias morfológicas, culturales y patogénicas entre los 21 grupos. Basado en la caracterización morfológica, cultural y patogénica, así como el análisis de secuencias de la región ITS se encontró que los aislamientos corresponden a Botrytis cinerea.
IKHFA’ “DWIPROSES FONOLOGIS dan KAIDAH FONOLOGINYA”
Authors: Anam Faqihul Agus
Published: August 2019

This research aims to describe phonological processes (PP) of ikhfa, as object of Qur’anic Phonology, and  the phonological rule of  ikhfa by Generative Phonology approach. In addition, this aims to prove the duality of PP ikhfa too.  The data are al-Hashmi’s data (2004) that is wrtitten in his theses. The goal of aplicated this model of data is keeping validity of data. The result shows that PP of ikhfa’ is the duality of PP, namely consonant asimilation and vocalic nasalitation. The PP rule of PP ikhfa’ is [n] à/n/ [α ant] [β cor]/_ [α ant]. It means that arabic nasal sound [n] can be pronounced as phonem /n/ with [+ ant] [+ cor] property of distingtive feature if tha nasal sound [n] located at sound environment with [+ ant] property of distinctive feature.

 

Key words: Phonological Processes (PP), Ikhfa’, Quranic 

  Phonology, Generative Phonology, Distinctive   Feature
DINAMIKA KEBUDAYAAN ISLAM MELAYU DI NUSANTARA
Authors: Pulungan Jufri Suyuthi
Published: August 2019

The socio-cultural community of Palembang identifies itself as a Malay ethnic group. As a Malay family, Palembang's location is very strategic, so many foreign visitors who visit or settle in Palembang, among them, ethnic Chinese and Arabs and other foreigners. In turn, not a few of these migrants actually settled in Palembang, including, ethnic Chinese (Tionghoa). It is estimated that since the 7th century AD, there has been established trade relations between China and Palembang, although written sources mention that the peak of trade relations occurred in the 10th-16th century AD. On the post trip of Commander Cheng Ho three times to Palembang (1413-1415), Muslims from China flocked to come to Palembang. Lehih far away, Cheng Ho's second coming to Palembang in 1414, carrying 63 ships with 28,560 passengers. Furthermore, referring to the Barnes chronology, in the 13th century AD at least 83,980 Chinese stopped in to Palembang, mostly Muslims, because China was dominated by the Ming Dynasty, a symbol of Muslim rule in China. To commemorate the services of Admiral Cheng Ho in the spread of Islam in Palembang, ethnic Chinese Muslims took the initiative to establish Masjid al-Islam Muhammad Cheng Ho located in Jakabaring. The existence of the Cheng Ho Mosque has brought different colors and shapes with other mosques in the city of Palembang. Cheng Ho Mosque has a specification of architectural form and ornament on Cheng Ho Mosque, both structural and non structural showing the acculturation of Chinese (Islamic), Islamic (Arab), and local culture (Malayan Palembang) elements. The existence of Cheng Ho Mosque Palembang not only serves as a place of worship. But also the place of events of Islamic and civic activities and guidance for mu'alaf, especially derived from ethnic Chinese. Thus, the existence of Cheng Ho Palembang Mosque is not only a place of worship typical of Tionghoa Islam, but also a new portrait of Malayan Malay Islam.Keywords: Cheng Ho Palembang Mosque, Acculturation, and Malay Islam
The Development of Analytic Team Collaborative Learning Model Based on Brain-Based Learning (BBL) for Junior High School Science Learning in Agroecosystem Areas
Authors: Mertha Yolanda Leony Agustia , Mudakir Imam , Prihatin Jekti
Published: August 2019

Abstract

Students in the agroecosystem area are generally less active because the teacher does not utilize the potential of the surrounding agroecosystem. This can be overcome by applying Brain-Based Learning (BBL) approach combined with AT collaborative learning model. This study aimed to produce Analytic Team learning model based on Brain-Based Leaning (AT-BBL) that is valid, practical, and effective, and also improves the students' critical thinking skills and learning outcomes. This study used R&D with 4D development model which only carried out three stages, namely define, design, and development without using the disseminate stage. The average validation is 86.98 (highly valid). The average percentage of teacher responses is 92.94%, and the average percentage of student responses is 91.22% which is very practical.

 

Keywords: Agroecosystem, BBL approach, Analytic Team Learning Model, Collaborative Learning
Bioinformatics Analysis to Construct Cellulose-binding Module Synthetic Gene and Design Primer
Authors: Wahyuni Febriana Dwi , Fuad Asrul Muhamad
Published: August 2019

Cellulose-binding module (CBM) is a protein domain commonly found in various types of cellulase enzymes. The function of this CBM can be used for the binding process and the immobilization of a protein in the cellulose matrix. CBM can be obtained from several organisms, one of them is Trichoderma reesei. To get a gene, it does not have to be isolated from the original organism. Gene sequences can be obtained synthetically through bioinformatics analysis in accordance with the same gene sequences as those at Gene Bank. Bioinformatics analysis can be used to find new gene sequences or existing genes. This study aims to get a cbmsyn synthetic gene quickly and efficiently without reducing protein activity, which can then be ligated with other genes so that it functions as an immobilized enzyme. From the results of bioinformatics analysis, obtained DNA sequences measuring around 498 pb with 166 amino acid protein lengths. The sequence was modified by adding several restriction sites, namely BamHI, AfeI, and ScaI. The DNA sequences obtained were optimized with the Pichia pastoris codon.
De baixo para cima, de Eliane Costa e Gabriela Agustini
Authors: Silva Maurício
Published: August 2019

O mapeamento de práticas culturais “alternativas”, isto é, concebidas e realizadas fora do circuito cultural mais “tradicional”, além da discussão de conceitos que se vinculam, direta ou indiretamente, a esse universo, são o tema do livro sugestivamente intitulado De baixo para cima, organizado pelas pesquisadoras e agentes culturais Eliane Costa e Gabriela Agustini. Buscando apresentar reflexões e pontos de vista variados no campo dos estudos da cultura, da inovação e da economia criativa, destacando processos criativos, de engajamento e de colaboração e, portanto, invertendo a tradicional relação cultural entre seus agentes (de cima para baixo), ao propor uma relação de baixo para cima, as organizadoras propõem tratar de experiências que têm por base as ideias de compartilhamento e de construção horizontal do saber, não raras vezes dialogando com a noção de cultura periférica.
Som tridimensional para deficientes visuais
Authors: Mello Adriane Cristine Kirst Andere de , Vieira Milton Luiz Horn , Nassar Victor
Published: August 2019

Neste artigo são apresentadas algumas discussões teóricas que embasam uma das pesquisas em desenvolvimento no designlab/UFSC. O objetivo principal é investigar a construção, de um dispositivo sonoro que facilite na localização e locomoção de deficientes visuais. Parte-se da tridimensionalidade sonora e de seus princípios históricos nas vanguardas artísticas, bem como, alguns seus desdobramentos na arte contemporânea. Na pesquisa são relacionados estudos a respeito do desenvolvimento social e multissensorial do público alvo, com Vygostsky (1997) e (2002) e experiências da arte sonora, a partir de Luigi Russolo (1992) e (1996), John Cage (1985) e (2007) e R. Murray Schafer (1991) e (2001). Por fim, são introduzidos procedimentos técnicos necessários para a construção do protótipo.
Vestígios do silêncio
Authors: Santos Iago Moura Melo dos , Beck Maurício
Published: August 2019

Neste teatro textual, refletimos sobre o silêncio em três atos: 1. consideramos a significância do silêncio, a partir de Orlandi e em cotejo com outros autores; 2. analisamos o editorial do Lampião da esquina, com o objetivo de compreender como o si dos sujeitos homossexuais é falado em relação ao gueto e como esse dizer constitui resistência à censura moral imposta pela língua-de-espuma da ditadura militar; 3. evocamos asignificância do vestígio (trace) em Ricoeur e da ausculta em Heidegger, para especular sobre a escuta analítica em relação à temporalidade do silêncio. Para nós, o silêncio pode ser interpretado como a terceira margem do Rio Lethe (Ideologia), em relação à base material da língua (primeira margem), em que se dão os processos discursivos (segunda margem).
Factors Affecting Sustainable Apparel Consumption in Emerging Countries: A Systematic Literature Review
Authors: Hasbullah Nornajihah Nadia , Sulaiman Zuraidah , Mas'od Adaviah
Published: August 2019

The growth of sustainable apparels provides grounding for the emergence of a new consumer market. Surprisingly, this movement has not only taken place in developed countries but also in emerging countries. To the best of the authors’ knowledge, no systematic reviews have been carried out on sustainable apparels, focused specifically on emerging countries. The goal of this systematic review is to analyse the existing literature on various factors that influence sustainable apparel consumption in emerging countries, as well as presenting future research directions. This detailed literature review is guided by the PRISMA Statement (Preferred Reporting Items for Systematic reviews and Meta-Analyses) review method, and its searches encompass sources such as Web of Science, Scopus and Google Scholar databases which, in result, identified 19 related studies. Furthermore, the reviewers segregated the factors into four major domains which include value, subjective norm, perceived behavioural control and knowledge. The results of this review demonstrate that most customers in the emerging countries have already experienced a growing interest in sustainable apparel with a strong development of knowledge, great concern, values and social circle. In sum, this systematic literature review provides an insightful information about sustainable apparel purchase behaviour and helps academicians, manufacturers and retailers to position and market their sustainable clothing brands.
PENGARUH HASIL PERKEBUNAN KEMIRI TERHADAP KEHIDUPAN SOSIAL EKONOMI MASYARAKAT DESA BENTENG TADO KECAMATAN LEMBOR SE LATAN KABUPATEN MANGGARAI BARAT NUSA TENGGARA TIMUR
Authors: Chandra Kamilus Adi , Jayanti Mustika Arif
Published: August 2019

Masyarakat Desa Benteng Tado pada umumnya memiliki banyak perkebunan kemiri. Kemiri merupakan tanaman pohon asli indo-malaysia yang bijinya di manfaatkan sebagai sumber minyak dan rempah-rempah dan sangat berguna bagi masyarakat dunia. Tujuan dari penelitian ini adalah untuk mengetahui  apa pengaruh hasil perkebunan kemiri terhadap kehidupan sosial ekonomi masyarakat Desa Benteng Tado Kecamatan Lembor Selatan Kabupaten Manggarai Barat Propinsi Nusa Tenggara Timur.Metode yang digunakan dalam penelitian ini yaitu metode korelasional. Data hasil penelitian dianalisis secara statistik dengan teknik analisis data menggunakan pengukuran koefisien pearson produck moment dengan menggunakan program bantu SPSS 20 for windows.Berdasarkan hasil uji statistik pearson product moment correlations, diketahui nilai koefisien korelasi antara hasil perkebunan kemiri dengan kehidupan sosial ekonomi sebesar =0,937 dengan signifikansi =0,000. Nilai sig.=0,000<0,05, sehingga hipotesis yang diajukan diterima. Hal ini menunjukan bahwa ada pengaruh antara hasil perkebunan kemiri dengan kehiduan sosial ekonomi masyarakat Desa Benteng Tado Kecamatan Lembor Selatan Kabupaten Manggarai Barat Nusa Tenggara Timur
PENGARUH MODEL PEMBELAJARAN GROUP INVESTIGATION TERHADAP KEMAMPUAN MENULIS ARTIKEL ILMIAH PADA MAHASISWA PENDIDIKAN GEOGRAFI
Authors: Wardani Nila Restu , Sari Yuli Ifana
Published: August 2019

Model pembelajaran Group Investigation mengarahkan mahasiswa untuk menemukan informasi berdasarkan kenyataan di lapangan. Hasil penemuan mahasiswa dapat dituliskan melalui karya illmiah dalam bentuk artikel ilmiah. Mahasiswa menuliskan laporan hasil investigasi di lapangan berdasarkan kaidah-kaidah penulisan yang logis dan sistematis. Jenis penelitian ini adalah penelitian Quasy Experiment (eksperimen semu). Subjek penelitian yaitu mahasiswa kelas A (kelas eksperimen) dan B (kelas kontrol) Program Studi Pendidikan Geografi FIP Universitas Kanjuruhan Malang semester ganjil 2016/2017. Instrumen yang digunakan yaitu rubrik penilaian untuk mengukur kemampuan menulis artikel ilmiah. Data hasil penilaian artikel ilmiah mahasiswa kemudian dianalisis menggunakan t-test dengan taraf signifikan 5%. Selanjutnya dilihat rata-rata nilai kemampuan menulis artikel ilmiah yang lebih tinggi untuk mengetahui ada tidaknya pengaruh model Group Investigation. Perolehan data menunjukkan rata-rata nilai kemampuan menulis artikel ilmiah pada kelas eksperimen 83,33 dan kelas kontrol 72,27. Rata-rata nilai kelas eksperimen lebih tinggi daripada kelas kontrol dan hasil analisis H0 menunjukkan nilai sig.2-tailed=0,000 atau < 0,05. Jadi, H0 ditolak dan H1 diterima atau model pembelajaran Group Investigation berpengaruh terhadap kemampuan mahasiswa menulis artikel ilmiah.
PERUBAHAN PENGUNAAN LAHAN DAN PENGARUHNYA TERHADAP PERUBAHAN IKLIM KOTA MALANG
Authors: Hamdani Akhmad Faruq , Susanti Nelya Eka
Published: August 2019

Perkembangan kota dengan semakin meningkatnya jumlah penduduk akan meningkatkan kebutuhan terhadap lahan. Perubahan lahan terbuka menjadi lahan tertutup akan meningkatkan suhu udara di wilayah perkotaan. Tujuan dari penelitian ini untuk menganalisis perubahan penggunaan lahan dan pengaruhnya terhadap perubahan suhu udara di Kota Malang pada 25 tahun terakhir. Hal ini berkaitan dengan banyaknya perubahan lahan terbuka menjadi lahan tertutup di Kota Malang. Tahapan penelitian yang dilakukan yakni; 1) mengumpulkan data yang dibutuhkan dalam penelitian; 2) Melakukan analisis kepadatan penduduk Kota Malang, 3) Melakukan analisis suhu udara di Kota Malang yang kemudian dihitung rata-rata tahunan dan rata-rata bulanannya; 4) Melakukan analisis regresi linier sederhana untuk  menghitung pengaruh antar variabel; 5) Melakukan survey lapangan untuk mengetahui kecocokan antara hasil analisis yang telah didapatkan dengan kondisi di lapangan. Berdasarkan uraian hasil penelitian di atas diperoleh hasil bahwa kepadatan penduduk Kota Malang pada tahun 1991 adalah 6369,65 jiwa/km2 dan pada tahun 2016 adalah 7734,26 jiwa/ km2. Terdapat kenaikan ± 1000 jiwa/ km2 dalam 25 tahun. Berdasarkan hasil analisis suhu udara Kota Malang selama 25 tahun diperoleh telah mengalami rata-rata kenaikan suhu udara 1,590C, dengan suhu udara bulanan tertinggi terjadi pada bulan April 2016 dan suhu udara terendah terjadi pada bulan Agustus 1995 dengan suhu udara 21,5810C. Kepadatan penduduk berpengaruh terhadap penggunaan tata guna lahan dan berpengaruh terhadap peningkatan suhu udara di Kota Malang dari tahun 1991 - 2016. Kepadatan penduduk di Kota Malang memiliki pengaruh sebesar 49,6% terhadap perubahan suhu, sedangkan 50,4% peningkatan suhu dipengaruhi oleh variabel lain
PENGARUH PEMBELAJARAN MIKRO TERHADAP KESIAPAN PROGRAM MAGANG III MAHASISWA PRODI PENDIDIKAN GEOGRAFI
Authors: Sari Yuli Ifana , Wardani Nila Restu
Published: August 2019

Kematangan calon guru menjadi tolak ukur yang digunakan untuk mewujudkan guru yang berkompetensi di bidangnya. Tujuan penelitian ini adalah untuk menganalisis dan mengetahui: pengaruh yang signifikan antara pembelajaran mikro terhadap kesiapan program magang III. Populasi adalah mahasiswa Pogram Studi Pendidikan Geografi semester VIII yang telah menempuh matakuliah pembelajaran mikro dan magang III sejumlah 156 mahasiswa. Teknik sampling dalam penelitian ini adalah Proportional random sampling. Instrumen penelitian yang digunakan yakni penilaian kemampuan merencanakan pembelajaran dan kemampuan melaksanakan pembelajaran. Pengujian hipotesis dalam penelitian ini menggunakan t-test.
IMPLEMENTASI MODEL PEMBELAJARAN JIGSAW UNTUK MENINGKATKAN KEAKTIFAN DAN HASIL BELAJAR SISWA KELAS X SMA PLUS ‘BUSTANUL ULUM’ PUGER JEMBER TAHUN AJARAN 2016/2017
Authors: Kartika Novita , Sakdiyah Siti Halimatus , B Roni Alim
Published: August 2019

Keaktifan belajar siswa kelas X-D sangat rendah dan hasil ulangan harian dan ulangan tengah semester tahun pelajaran 2016/2017 pada semester genap masih belum memenuhi Kriteria Ketuntasan Minimal (KKM). Penelitian ini bertujuan untuk meningkatkan Keaktifan dan Hasil Belajar siswa kelas X-D SMA Plus ‘Bustanul Ulum’ Puger Jember melalui penerapan model pembelajaran Jigsaw. Penelitian ini menggunakan pendekatan kualitatif dengan jenis Penelitian Tindakan Kelas (PTK) yang dilakukan dalam dua siklus. Siklus 1 dengan pokok bahasan perairan darat, sedangkan pada siklus 2 dengan pokok bahasan perairan laut. Hasil penelitian menunjukkan bahwa untuk keaktifan siswa menunjukkan ketercapaian pada siklus 1 sebesar 67,7 % yang berada pada kriteria aktif sedangkan pada siklus 2 mencapai 83,4% yang berada pada kriteria sangat aktif. Hal ini menunjukkan bahwa terjadi peningkatan dari siklus 1 ke siklus 2 yaitu sebesar 15,7%. Hasil belajar pra tindakan rata-rata nilai siswa mencapai 53,3 dengan jumlah kentutasan klasikal 13,88%, siklus 1 nilai rata-rata siswa mencapai 62,3 dengan jumlah ketuntasan klasikal 33,3%, sedangkan pada siklus 2 mencapai 73,3 dengan jumlah ketuntasan klasikal 77,8%. Ini menunjukkan bahwa antara pratindakan dan siklus 1 mengalami peningkatan sebesar 19,5% dan antara siklus 1 dan siklus 2 mengalami peningkatan sebesar 44,5%. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa implementasi pembelajaran model Jigsaw memenuhi kriteria sangat baik. Pembelajaran model Jigsaw meningkatkan keaktifan dan hasil belajar mata pelajaran geografi siswa kelas X-D SMA Plus ‘Bustanul Ulum’ Puger Jember.
PENGEMBANGAN PARIWISATA ALAM DI KECAMATAN PONCOKUSUMO MENGGUNAKAN SISTEM INFORMASI GEOGRAFIS BERBASIS WEB
Authors: Saraswati Adinda Riskia , Malik Jamil Achmad Maulana
Published: August 2019

Kecamatan Poncokusumo merupakan daerah agrowisata di Kabupaten Malang, Tujuan penelitian ini membuat pengembangan pariwisata dengan menggunakan sistem informasi geografis berbasis web sehingga informasi tersebut dapat diakses dengan mudah oleh masysrakat. Metode yang digunakan dalam penelitian ini adalah kuesioner, wawancara dan dokumentasi. Subyek dalam penelitian ini adalah wisatawan yang datang ke obyek wisata, pengelola obyek wisata alam yang berada di Kecamatan Poncokusumo, tokoh masyarakat  di sekitar obyek wisata alam dan Dinas Pariwisata Kabupaten Malang. Penelitian ini merupakan penelitian kualitatif menggunakan analisis SWOT dalam pengembangan pariwisata alam di Kecamatan Poncokusumo. Berdasarkan hasil penelitian, banyak sekali potensi alam yang berada di Kecamatan Poncokusumo antara lain coban bidadari, coban pelangi, ledok ombo, gunungsari sunset, river tubing ledok ombo dan juga river tubing sedaer.
Dutch Healthcare Professionals Experiences of Assisted Dying: A Constructivist Qualitative Study Conducted in a Chronic Disease Care Centre and Hospice.
Authors: Lewis Deborah , Preston Nancy
Published: August 2019

Background: Assisted dying is a contemporary issue, but comprehensive consideration of healthcare professionals’ experiences has been lacking. This study sought to gain a deeper understanding of professionals’ experiences of assisted dying to inform the global debate surrounding its implementation.
Methods: This constructivist, qualitative study, recruited twenty-one physicians, nurses and therapists from a Dutch chronic disease care centre and a hospice. Data were gathered in semi-structured interviews, conducted in English. Questioning focused on professionals’ experiences along a clinical trajectory from an initial request to beyond the death. Data were subjected to thematic analysis to identify main and subthemes.
Results: Analytical procedures generated four broad themes ‘Assessment and its Challenges’, ‘Preparing Staff and Learners’, ‘Assisting a Death’ and ‘Bereavement Care and Beyond’, supported by subthemes. Assessment of requests involved all professional groups and required open dialogue, exploration of fears, palliative care optimisation and psychological evaluation. Such measures resolved the majority of requests.
Assisted deaths were challenging, required careful management and were not perceived as normal. Administration of lethal drugs and reporting procedures were stressful for physicians. Structured debriefing and proactive psychological support were valued by all professionals, but resolving their emotions took time. Some physicians required a recovery period creating equity of access issues. Life and care experience aided the preparation of professionals, but resilience was also needed. Support for the provision of assisted dying was overwhelming, but this was unqualified in only a third of participants.
Conclusions: Assisted dying creates significant challenges for healthcare professionals who require preparation and support. This is likely to require enhanced levels of palliative care education, legislative advice, and proactive psychological support to ensure professionals’ own well-being. Meeting these needs will have financial implications which should be addressed prior to implementing legislation which permits assisted dying.