bluuebunny/crossref_metadata_2025 huggingface dataset:
Manifest and latent social groups: Phenomenon, evolution, determinants. Part 1
Authors:   Institute of Psychology RAS, Tolochek Vladimir A.
Published: October 2022

Objective: to study the features of the social micro- and meso-environment as potential conditions for the formation, functioning and evolution of latent social groups. Hypotheses: 1. Various conditions of the social environment are not regarded as equivalent by people (persons of different genders, ages, working in different fields of activity, having different social experience, etc.). 2. The conditions of the social environment have different subjective significance for people and collectively represent relatively autonomous and closed social spaces. Methods: historical and theoretical analysis, empirical research (questionnaire), multidimensional methods of parametric statistics. According to the author’s methodology (questionnaire “Dynamics of professional life style” - DPLS), respondents assessed the role of social environment conditions as “factors of professionalism”, the dynamics of their professionalism from 20 to 65 years (retrospectively to the current age and prospectively – predicting the dynamics of subsequent evolution); their socio-demographic and official characteristics were also recorded. 482 employees, men and women aged 30-50 were interviewed (132 civil servants, 129 engineers and heads of departments of industrial enterprises, 221 managers). The results of the empirical study confirm the working hypotheses. Groups of conditions of different social spaces, conventionally called “Relatives”, “Interpersonal relationships”, “Family environment”, “Work environment”, “Meso-environment”, act as dominant or subdominant spheres of human activity, predetermining many differences between them. In the process of socialization, people form peculiar stable and universal mechanisms of activating and translating social experience; the lack of such experience often contributes to a person’s being less open and receptive to other conditions of the social micro- and meso-environment, to their being less socially successful. Briefly, the description and study of latent social groups is relevant since it helps to identify “subtle” mechanisms of self-organization of people into social communities.
Perfectionist self-presentation and altruistic attitudes during adulthood
Authors:   Belarusian State University, Truhan Elena A. , Savchuk Olga N. ,   Belarusian State University
Published: October 2022

The problem of effective tactics of personal self-presentation in various situations of social interaction is becoming increasingly important. The phenomenon of perfectionism as a person's desire for perfection, exceptional achievements and admiration from others, is becoming increasingly common both in professional and personal spheres. Objective: to identify the relationship between perfectionist self-presentation and altruistic attitudes in different periods of adulthood. It is hypothesized that there is gender and age characteristics and the interrelationships of perfectionist self-presentation and altruistic attitudes during adulthood. The study sample consisted of 90 respondents (men and women) aged 20 to 75 years (Minsk). Three periods of adulthood were compared: early (20-40 years), middle (40-60 years) and late (over 60 years). To diagnose perfectionist self-presentation, the Russian–language version of P. Hewitt's Perfectionist Self-Presentation Scale was used (adaptation by A. A. Zolotareva); to determine the manifestation of altruistic atti tudes, the methodology for diagnosing socio-psychological attitudes of the individual (O. F. Potemkin) was used. The authors obtained the data on gender and age characteristics and interrelations of perfectionist self-presentation and altruistic attitudes during adulthood. Through altruistic actions, men strive to create an image of a perfect person, demonstrate socially desirable behavior (altruism as a secondary benefit and a tool for self-promotion). With age, the level of perfectionist self-presentation decreases, and the manifestation of altruistic attitudes increases, reaching its peak in late adulthood. Empirically, the authors proved the existence of a relationship between perfectionist self-presentation and altruistic attitudes during late adulthood (the willingness to act for the benefit of others, to patronize people who suffer or experience difficulties, is associated with the desire to receive admiration and approval from others). Interpersonal interaction is shown to be regulated by empathy as well as by image and reputation goals, and altruism is one of the tactics of impression management. Taking care of one's reputation, public opinion, and image are important reasons for benevolence and prosocial behavior.
Character Design, Using MetaHuman Creator: Focusing on characters from the TV series ‘Arthdal Chronicles’
Authors:   The Korean Society of Beauty and Art, Moon Seo-Yeong , Kim Yeon-A , Lee Jeong-Hyun
Published: October 2022

In this study, character makeups were created from 5 main characters of the TV series ‘Arthdal Chronicles’, using MetaHuman Creator. It attempted to have a correct understanding of character makeup and recreate characters in consideration of historical background with a goal of completing perfect characters in the metaverse era by reviewing the tutorial of the MetaHuman Creator of Unreal Engine. For this, character makeups, historical background of ‘Arthdal Chronicles’ and 5 main characters were reanalyzed and reviewed through analysis of literature materials, previous studies and Internet resources. After learning how to use MetaHuman Creator, character makeups were eventually created. This process is essential for makeup specialists who are required to create characters by analyzing the scenario and characters. In this study, makeup specialists created characters who could lead industry 4.0, using computer. It is anticipated that makeup-IT convergence would further expand creative 3D character design and make a contribution to the continued growth and development of makeup and IT technologies.
Delineation of Stable High Yielding Lentil Genotypes Through HA-GGE and REML/BLUP Method for Gangetic Alluvial Zone of India
Authors: Bhattacharya Sudip , Das Arpita , Banerjee Joydeep , Mandal Swarupananda , Mandal G.S.
Published: October 2022

Background: Delineation of high yielding stable lentil genotypes (G) with least environmental (E) influence is a challenging issue. In the present study, an attempt has been made to unravel the magnitude of the effect of GEI for appraising the stable lentil genotypes through deploying HA-GGE biplot along with linear unbiased prediction (BLUP) using restricted maximum likelihood (REML) and other stability indices. Methods: The present experiment was conducted with 30 promising lentil genotypes grown at four different locations of West Bengal during two consecutive years for recording grain yield. Subsequently, G × E interaction was deciphered integrating HA-GGE and REML/BLUP method. Result: Genotypes appraisal detected presence of adequate genetic variability and significant G × E interaction. Integration of GGE biplot along with REML/BLUP precisely delineated G30 (IC 521442); G9 (BM 5); G11 (IC 560212) and G8 (Moitree) as stable and desirable lentil genotypes with coherent response across the locations over the years.
Acervos do sexagenário Centro de Planejamento Oscar Niemeyer da Universidade de Brasília
Authors: Oliveira Soares Eduardo
Published: October 2022

A nova capital do Brasil, Brasília, e a Universidade de Brasília (UnB), inauguradas em 1960 e 1962, respectivamente, são frutos da crença na capacidade cultural nacional e de vultoso investimento no desenvolvimento do país. Com o intuito de assessorar tecnicamente a administração da Universidade em relação aos assuntos atinentes ao planejamento físico, no mês seguinte a sua inauguração foi criado o Centro de Planejamento (Ceplan), tendo como primeiro coordenador Oscar Niemeyer. Esse centro assimilou o espírito da época da sua implantação, criando e reunindo relevantes produções que podem ser caracterizadas como diferentes acervos: seu edifício faz parte do acervo arquitetônico da UnB e conta com conta com obras de arte integradas; os espaços internos do prédio abrigam mobiliário original e maquetes de projetos relevantes; e a documentação acerca dos planos e projetos de infraestrutura em suas diversas escalas e especificidades registram uma longa trajetória. Este artigo apresenta os acervos do sexagenário Ceplan e os situam, em alguns aspectos, enquanto amostra de outros relevantes acervos da Universidade.
Tecnología al alcance del adulto mayor: proceso de fabricación de mueble inteligente Dalila con enfoque a usuario adulto mayor
Authors: Brenes-Mora Ileana , Artavia-Camacho Julianan , Albán-Varela Soledad
Published: October 2022

Dalila es un mueble aéreo inteligente de cocina cuyo objetivo es facilitar el almacenamiento y las actividades cotidianas de los adultos mayores. Este mueble hace uso de recursos tecnológicos para generar un espacio seguro en el que se pueda desenvolver el usuario, mediante alertas que sean percibidas por todos los sentidos. La tecnología presente en este producto es sencilla y poco perceptible, por lo que el producto es bastante intuitivo. Este artículo presenta la estrategia tanto de diseño como de fabricación de un mueble inteligente que facilita la interacción de adultas y adultos mayores y activos en el área de la cocina, un producto que no limite las posibilidades del usuario si no que más bien genere un ambiente seguro y libre de peligros.
If the Punishment Should Fit the Crime, How Serious Are 75 Crimes? An Empirical Study
Authors: McGee Robert W. , Petrides Yanira , Gelman Wendy
Published: October 2022

This paper reports on the results of a survey of more than 500 young and middleaged college-educated adults regarding their views on the seriousness of 75 crimes. If the goal is to apply the legal principle that the punishment should fit the crime, one must first know how serious the crime is. This study ranks 75 crimes in terms of seriousness, using a Likert Scale where 1 is not at all serious and 100 is extremely serious. Some comparisons of mean scores were made, and p-values were computed, to determine whether certain crimes are significantly more serious than other crimes. Is the life of a prostitute more or less valuable than the life of a drug dealer, politician or lawyer? Are some kinds of discrimination more serious than others? In the case of statutory rape, should the criminal be punished more severely if it is a man rather than a woman, or should their punishments be equal? These and other questions are answered in this study. The authors grant permission to replicate this study using their survey instrument.
Features of modern genesis of the Ishim steppe watershed plain soils
Authors: Kravtsov Yu. V. , Smolentseva E. N.
Published: October 2022

The genesis main directions of the Ishim steppe watershed plain soils depending on their economic use (arable land, forest belt, abandoned land) during the 1950s – 2020s were revealed. Within the studied region, soils were diagnosed on lands of different use. It is shown that the regional morphogenetic feature of all watershed plain soils is the tonguing of the humus horizon, which is reflected in their classification status by the allocation of a dark-tonguic subtype of the soils. Differentiation of the agrodarkhumus horizon into two subhorizons under the influence of plane-cutting processing was revealed in the agrozem, prevailing by area. The manifestation of postagrogenic transformation of soils occurring under forest belts and under deposits with herbaceous vegetation is determined. Postagrogenic soils are characterized by a granular structure, higher reserves of humus and total nitrogen in a layer of 0–20 cm compared to agrozems. In the soil of the forest belt, a coarse-humus neo-horizon was formed, which is not typical of steppe soils. The soil under abandoned for a long time grassland has signs of dark humus horizon progradation to a state close to a virgin one. The additional surface moistening of micro-subsidence soils causes them to have a higher humus content and its reserves in the 0–100 cm layer, deeper leaching of carbonates, the formation of a clay-illuvial horizon in the carbonate-free zone and prevents the formation of a gypsum horizon. The groundwater level raising in the modern period, which is a consequence of the mass plowing and functioning of impenetrable protective forest belts in the study area, caused the appearance of neo-hydromorphism in watershed plain soils and the formation of quasi-clay subtypes. The results indicate the regional specificity of the genetic properties of the Ishim steppe watershed plain soils that distinguish them from their European counterparts, as well as the influence of agrogenic transformation as an anthropogenic factor on them. This influence is reflected in the morphology of soils, their humus state, the nature of the carbonate and gypsum profiles, the processes of halogenesis in them and the variety of salt profiles.
A Scientometric Analysis on Cardiac Echinococcosis
Authors: UYAR Cemile , DİNDAR DEMİRAY Emine Kübra , OĞUZ MIZRAKÇI Serpil , ŞAHİNOĞLU Mustafa Serhat
Published: October 2022

Cardiac echinococcosis is a rare but mortal disease. The primary goal of this study was to quantitatively examine, using bibliometrics tools, the publications and assess the hot issues and new directions in cardiac echinococcosis research from 1970 to December 2021. We only included "journal articles" and "reviews" in the study. The keywords "cardiac echinococcosis", "cardiac hydatid disease’ or "echinococcal heart disease" were used for the search. The search covered the years 1970 through December 2021. The data was extracted from the Web of Science database. Vosviewer software was used for network mapping. The research findings, which were based on the search strategy used, showed that between 1970 and 2022, there were 425 articles and reviews on cardiac echinococcosis that had been indexed in the Wos database. Most of the papers were from Türkiye (n=152). India (n=29), Iran (n=29), Tunisia (n=26) and France (n=22) were the other top publishing countries. The first publication was published in 1991. Although the number of publications increased after 1996, it emphasizes an irregular distribution. The publications were cited 3900 times in total and 9.18 times per publication, and the mean H-index was 28. There was an increase in the number of citations after 1995. There were 151 publications from Türkiye, and these publications were cited 1,327 times total, 8.79 per publication, and the mean H index was 18. The number of publications was not at the expected rate. The findings of our study may be helpful to researchers researching cardiac echinococcosis.
Standard expert tasks in law cases with regard to articles 207.3, 280.3 of the Criminal Code of the Russian Federation, article 20.3.3 of the Code of Administrative Violations of the Russian Federation and possible procedures of their solution
Authors: Zharkov Igor V. , Konstantinova Veronika V.
Published: October 2022

The subject of the study is standard expert tasks subject to solving in linguistic and complex psychological and linguistic forensic enquiries with regard to cases on the charge of speech act of crimes or speech delicts related to the concept of use of Armed Forces of the Russian Federation. The relevance of the analysis resulted from the status of the corresponding criminal and administrative statutory regulations being innovations and from the fact that currently the practices of both commissioning of expert evidence and performance of expert examinations with regard to such cases are in course of development. In the course of the study, the expert tasks related to the sphere of the linguistic and psychological special conusance, stemming from the essential properties and characteristics of law cases pertaining to the denoted category, corresponding to the general task of forensic enquiries stated by article 2 of the “Act on state forensic activities in the Russian Federation” and reflecting developing administration of law were elicited, series of thoughts about possible procedures of solution of the expert tasks were expressed and proved. Based on the results of the study described in the article, the list of the standard expert tasks for the law cases pertaining to the denoted category is suggested.
Synergistic approach to the study of stability and mobility of the word meaning (on the material of polysemant red)
Authors: Kanakina Galina I. , Kezina Svetlana V.
Published: October 2022

We analyze the semantic structure of the polysemant red. The purpose of study is synergistic understanding of semantic stability and mobility of a polysemantic word. The main methods of the linguistic research are comparative, additive, comparative-historical, historical-comparative and method of component analysis. The problem of the stability and mobility of the word meaning is associated, on the one hand, with a significant accumulation of actual material, which requires explanation, on the other hand, with insufficient explanatory power of traditional approaches to study of semantic asymmetry and objective difficulties in reconstructing the preliterate state of a word semantics. The novelty of the study is determined by a synergistic approach to the study of the stability and mobility of the word meaning, which involves considering semantic asymmetry in a synergistic system. It is revealed that the unity of stability and mobility of polysemant semantic structure as a hierarchically organized system of sememes provides its dynamic equilibrium. In the process of lexeme evolution, dynamic equilibrium is disrupted due to hypertrophied growth of the meant with one meaning, that leads to the instability of the system and cardinal changes in it. It is justified that the semantic stability of a polysemant red is manifested in its preservation of the sememe “red” and is ensured by homeostaticity and hierachicity, and the semantical mobility is manifested, in particular, in the actualization of one sememe or some sememes, and in the redemption of others, and is determined by the incompletness, instability and nonlinear style of a polysemantic word as a synergistic system. We conclude that it is possible to use the results of the study for a dynamic (synchronous-diachronic) description of polysemantic words.
Tambov ergonyms dating back to the word “wolf”
Authors: Dzyuba Maria S.
Published: October 2022

We are making an attempt to establish the producing base of Tambov ergonyms, including the phrase “Tambov wolf”. We establish that the ergonym nomination is based on the katoikonym “Tambov wolves”. The coexistence of these onomastic facts in a single toponymic space indicates the presence of regional features as unifying territorial features, including with the help of linguistic means (for example, an unofficial onomastic nomination in the self-determination of residents of the village of Otyasy, Sosnovsky District, Tambov Region: “We are Tambov Salamatniks”). We prove that such stable phrases as “Tambov wolf” and “Tambov Salamatniks” are by their origin connected with folk colloquial speech, reflecting such a concept as “dialectal onomastics”.
Cognitive approach to the study of precedent names in media discourse (based on the material of Russian and French)
Authors: Razumovskaya Yulia M.
Published: October 2022

The object of study was precedent phenomena, or rather precedent names, and their functioning in modern Russian and French media discourse was considered as the subject of the study. Precedent names that perform appellative, cognitive, communicative, expressive, text-forming functions are strong elements of the text and are able to influence the mass consciousness. The frequency of their use in the materials of mass media discourse is steadily growing, which explains the relevance of the study. In the course of the study, the goal of analyzing precedent names was fulfilled, the comprehension of which requires referring to the cognitive context REAL ECONOMY, which is a component of a private matrix that includes the concept PERSONALITY as a core. Using the method of cognitive-matrix analysis to describe the components of the matrix as a system of cognitive contexts or conceptual areas, it was revealed that when comprehending a precedent name in relation to the context REAL ECONOMY, the cognitive contexts APPEARANCE, PSYCHE AND STATUS of the concept PERSONALITY are actualized. It is proved that the STATUS cognitive context when referring to the REAL ECONOMY conceptual area is most often interpreted. The study made it possible to draw a conclusion about the importance of the text-forming function of precedent names, which have become an effective tool for speech influence, and the importance of studying the cognitive mechanisms of their functioning.
On the history of the Russian translation of Chinese new literature in the 1920–1930s
Authors: She Xiaoling , Li Mengya
Published: October 2022

The issue of literary relationship between China and Russia in the first half of the twentieth century remains relevant to contemporary Russian and Chinese literary studies. The purpose of this work is to examine the history of the Russian translation of Chinese new literature in the 1920s-1930s and explore how Soviet critics evaluated them. The paper provides a cultural-historical analysis and indicates that, in the USSR, the introduction to Chinese new literature was inextricably linked to the activities of Academician V.M. Alekseev in the 1920s, when systematic publication of the works of Soviet Orientalists was launched, and in the late 1930s, due to the persecution against the translation group, the intensity of the translation and publication of modern literary works began to wane. In the 1920s–1930s, the first translations, reviews, and literary-critical reviews appeared, most of which belonged to those who had direct contact with Chinese intelligentsia. Chinese cultural figures such as translators of Russian literature including Cao Jinghua and Xiao Can also played an important role in promoting modern Chinese literature in the USSR. Chinese new narrative prose was praised by Soviet critics for revealing a real picture of the changes in China. Much attention was paid to the thematic-ideological and ethical aspects of the works of Lu Xin and Mao Dun, who were deemed as “leaders” of modern Chinese literature in the USSR.
Personal data in the media sphere: the specifics of work
Authors: Maltsev Nikita D.
Published: October 2022

The protection of personal data in the media at the modern stage of technological development is a challenging task with many aspects that must be observed according to the legislation of the Russian Federation. The most pressing problems related to the collection, storage, use and protection of personal data in the media are considered. We make the systematization of the main stages in the history of the development of legislation in the field of personal data protection in Russia and abroad, an analysis was made of modern methods of processing, storing and transferring personal data in various countries of the world. The legislative acts of the Russian Federation, which apply to certain algorithms for the work of mass media with personal data, are considered separately. We analyze in detail the domestic judicial practice on cases of incorrect processing of personal data in the media. Based on the results of the generalization of analytical and statistical materials, methods for protecting data during their collection, processing and storage at various stages of media production are proposed. The recommendations received can be used in the practice of media editorial work and in the blogosphere.
Insulin-like growth factors and their carrier proteins in kidneys of rats with experimental diabetes, malignant tumor, and their combination
Authors: Frantsiyants E. M. , Bandovkina V. A. , Kaplieva I. V. , Surikova E. I. , Neskubina I. V. , Pogorelova Yu. A. , Trepitaki L. K. , Cheryarina N. D. , Kotieva I. M. , Morozova M. I.
Published: October 2022

Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.

The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (IGFBP), and markers of kidney tissue damage (IL-18, L-FABP, cystatin C, NGAL, and KIM-1) in male rats with diabetes mellitus, tumor growth, and their combination.

Materials and methods. The study included white outbred male rats (n = 32) weighing 180–220 g. The animals were divided into four groups (n = 8 each): group 1 – intact animals; controls (2) – animals with diabetes mellitus; controls (3) – animals with Guerin carcinoma; experimental group (4) – animals with Guerin carcinoma against the background of diabetes mellitus. Levels of IGF-1, IGF-2, IGFBP-1, IGFBP-2 and markers of acute kidney injury (IL-18, L-FABP, cystatin С, NGAL, and KIM-1) were determined in the kidney homogenates using enzyme-linked immunosorbent assay.

Results. Increased levels of acute kidney injury markers were found in the kidneys of male rats with diabetes mellitus alone and in combination with Guerin carcinoma. In the animals with diabetes mellitus, the levels of IGF-1, IGFBP-1, and IGFBP-2 were decreased on average by 1.3 times, and the level of IGF-2 was increased by 2.1 times compared with the values in the intact male rats. The elevation of IGF-2 / IGF-1 on average by 2.8 times indicated increasing hypoglycemia in the kidney tissue of the animals with diabetes mellitus and in the experimental group with diabetes mellitus and Guerin carcinoma. In the kidney tissues of the rats with Guerin carcinoma, IGF-1 and IGF-2 were elevated on average by 1.5 times, and IGFBP-2 was decreased by 1.7 times. In the animals with malignant tumors growing against the background of diabetes mellitus, IGF-2 and IGFBP-1 were increased by 2.3 and 1.7 times, respectively, and the levels of IGF-1 and IGFBP-2 were similar to those in the intact animals.

Conclusion. The study demonstrated abnormalities in the metabolic profile of the kidneys in male rats with experimental diabetes mellitus, Guerin carcinoma, and their combination.
The effect of age and a high-fat, high-carbohydrate diet on the development of arterial hypertension and kidney disease in the experiment
Authors: Mustafina L. R. , Logvinov S. V. , Naryzhnaya N. V. , Kurbatov B. K. , Maslov L. N.
Published: October 2022

Aim. To identify the structural foundations of the pathogenesis of arterial hypertension and kidney disease associated with a high-fat, high-carbohydrate diet and age.

Materials and methods. The study was carried out on male Wistar rats aged 60 and 450 days. The animals were divided into 4 groups: group 1 (n = 14) – intact rats (60 days old) fed with a standard diet for 90 days; group 2 (n = 14) – rats (aged 60 days) receiving a high-fat, high-carbohydrate diet for 90 days; group 3 (n = 14) – intact rats (aged 450 days) receiving a standard diet for 90 days; group 4 (n = 14) – rats (aged 450 days) fed with a high-fat, high-carbohydrate diet for 90 days. Clinical and instrumental research methods, enzyme-linked immunosorbent assay, and immunohistochemistry and histology techniques were used in the study.

Results. Feeding 60-day-old animals with a high-fat, high-carbohydrate diet resulted in an increase in body weight and abdominal fat, a rise in systolic blood pressure, and moderately pronounced histologic changes in the kidneys. In intact 450-day-old rats, age-related changes prevailed: changes in the myocardial mass, an increase in TGF-β1, morphological changes in the renal tubules and glomeruli. In 450-day-old rats receiving a high-fat, highcarbohydrate diet, the most pronounced increase in both systolic and diastolic blood pressure, a significant rise in serum fibronectin, and destructive changes in the renal tissue were noted.

Conclusion. Functional and biochemical signs of arterial hypertension and morphological changes in the kidneys were the most pronounced in 450-day-old rats fed with a high-fat, high-carbohydrate diet.
The Effect of Subchronic Administration of Soursop (Annona muricata) Leaf Aqueous Extract In Bax Expression on Gastric Glandular and Non Glandular Mucosal Epithelium of Rat (Rattus norvegicus)
Authors: Handayani Ety Sari , Nugraha Zainuri Sabta , Rauf Chandra Muhammad , Thoriq Yusa Muhammad , Hidayah Nurul
Published: October 2022

Soursop leaf water extract (SLWE) contains acetogenin compounds which are mitochondrial complex I inhibitors. This compound can reduce cellular ATP production and induce apoptosis via bax pathways, causing side effects on cells. Gaster is a digestive organ that has direct contact with acetogenin. Gastric cells contain mitochondria and undergo physiological apoptosis.This study aims to determine the effect of subchronic administration of SLWE on bax expression on glandular/non glandular mucosal epithelium gastric of rats. This study was conducted at Research Laboratorium, Medical Faculty, UII, 2019. This study uses post test only control group design. The subjects were 10 female rats, Spraque-dawley strain which was divided into 2 groups; the treatment and the control group. The treatment group received extract of SLWE at a dose of 1000 mg/kgBB/day for 30 days, while the control group received aquades, both were administered using sonde. Observation of bax expression was performed on each IHC preparation with bax antibody. The difference in bax expression between the control and treatment groups was tested by t-test. There were significant differences in the number of bax expressions in gastric glandular mucosa (p 0.038) and non-glandular gastric mucosa (p 0.027) between the treatment group and the control group. There was an effect of subchronic administration of SLWE on bax expression on mucosalepithelium for both, glandular and non-glandular of rat gaster. There were differences in the number of glandular gastric as well as non-glandular gastric mucosa epithelium which exerted bax between the control and treatment groups
Regulations In Liew Of Statutes In States Of Emergency In Indonesia
Authors: Ansori Lutfil
Published: October 2022

The enactment of a Government Regulations in Lieu of Laws during states of emergency raises problems. This is evident so in the enactment of Government Regulation in Lieu of Law No. 1 of 2020 which was formed based on an emergency but used the framework of normal legal regime. Such has led to legal uncertainty and is hence vulnerable to abuse. This research was conducted to answer the problems regarding: the application of emergency laws in Indonesia and the government regulations in Lieu of Laws during states of emergency. This paper used normative legal research conducted by means of statutory, case study, and conceptual approaches. The study concludes that there have been some developments in the application of emergency law in Indonesia, since the status of the current public health emergency s is categorized as an emergency that must be responded to by legal regime in a state of emergency. From the aspect of legal regulation, it is apparent that there are various forms of emergency laws in Indonesia, and each of these legal forms has a different impact on the regulation and its legal binding power. However, the diverse arrangements of emergency laws are not supported by the standard concepts of the state of emergency and these arrangements tend to overlap which has caused ambiguity in the arrangement of emergency law in Indonesia. government regulations in lieu of laws that are stipulated the states of emergency bear the status of emergency regulations. Therefore, the issuance of a government regulations in lieu of Las in the state of emergency must comply with the legal principles of the state of emergency. On this basis, the issuance of government regulations in lieu of laws in the state of emergency must firmly determine the period of its validity as a way to ensure that the existence of the government regulations in lieu of laws does not create legal uncertainty.
Problems Of Implementation Of Electronic Land Certificate Arrangements As Debt Guarantee
Authors: Pakpahan Kartina , Azharuddin Azharuddin , Leviyanti Leviyanti
Published: October 2022

The implementation of land registration and electronic mortgage installation is intended to provide efficiency to rights holders and related agencies in carrying out activities in the land sector. This study aims to determine the positive law regarding the legal certainty of the parties to the electronic land certificate which is used as debt guarantee and the role of the Notary/Official Certifier of Title Deeds in the implementation of the installation of mortgage rights. Using library research, normative juridical methods, analyzing data with a qualitative approach. The Minister of Agrarian and Spatial Planning/Head of the National Land Agency realizes digital-based land registration activities as stipulated in the Regulation of the Minister of Agrarian Affairs and Spatial Planning/Head of the National Land Agency Number 1 of 2021 whose implementation has been postponed. Land-electronic certificates can be used as collateral for debtors' debts by making a deed of granting mortgage which is made and signed before the Land Deed Maker Officer which is then registered at the local National Land Agency Office. The Electronic Mortgage System is implemented as stated in the Regulation of the Minister of Agrarian Affairs and Spatial Planning/Head of the National Land Agency of the Republic of Indonesia Number 9 of 2019, the results of the mortgage certificate are in the form of printed electronic documents.
The Religious Courts’ Authority To Adjudicate Disputes Based On Principal Agreements And Security Agreements Due To Different Choice Of Law
Authors: Widodo Sri
Published: October 2022

A Sharia Banking Agreement is often secured by the Deed Granting Mortgage. These two agreements are different types and have different burden of proof. However, the existence of Sharia Banking Agreements as principal agreements is not often secured by the choice of law under Deed Granting Mortgage. This research will elevate the position of the legal burden of proof between Sharia Banking Agreements and Deeds of Granting Mortgage along with the legal consequences due to different legal choices between the Sharia Banking Agreement and Deed Granting Mortgage based on a study of Court Decision No.499/Pdt.G/2021/PA YK in the Religious Court of Yogyakarta. This research applied a normative approach with the literature study method based on the court decision and regulation as primary legal materials and used secondary legal materials including books, journals, and other legal works that are related to the topic. From this research obtained that between Sharia Banking Agreement and the Deed Granting Mortgage that secures have different types of agreements and the different burden of proof. Although Deed Granting Mortgage is an additional agreement it must secure the principal agreement which is Sharia Banking Mortgage. Based on Court Decision No.499/Pdt.G/2021/PA YK, whereas the Deed Granting Mortgage regulated on the authority of the District Court in the event of a dispute but because the principal agreement is Sharia Banking Agreement, it has authority from Religious Court to examine and settle disputes.
Adipocyte-derived exosomal lncRNA related to Insulin Resistance in Obesity.
Authors: Wang Ying , Li Xiaona , Wu Yanhui , Zhang Meiyu , Bai Hua , Luo Peiliang , Yuan Yingdi , Yao Yuqian , Wen Juan
Published: October 2022

Introduction:Through exosome-mediated transportation, long noncoding RNAs (lncRNAs) can influence cellular function and mediate cross-talk among organ systems. However, current understanding of the roles of exosomal lncRNAs in the context of insulin resistance (IR) remains limited. Accordingly, this study was developed to examine patterns of differential lncRNA expression in blood-derived exosomes from a murine high-fat diet-associated IR (HFD-IR) mice model and to explore the functions of these lncRNAs.Methods:A microarray approach was used to assess the differential patterns of lncRNA expression in blood-derived exosomes when comparing control and HFD-IR mice. The observed changes in lncRNA expression were also validated in blood and skeletal muscle from obesity-associated IR model mice and in C2C12 myotubes that had been subjected to high-dose 0.5 mM palmitate treatment. Further studies of the origins of exosomal lncRNA AK018453 were performed through the use of siRNAs and exosomes that had been labeled with PKH26.Results:In total, HFD-IR mice exhibited 375 lncRNAs that were differentially expressed in their blood-derived exosomes as compared to healthy control mice. Pathway and gene set enrichment analyses suggested these targets to be enriched in the NF-kB, PI3K-Akt, Wnt, JAK/STAT, and glucagon signaling pathways. Additional studies revealed that these exosome-derived lncRNAs contained binding sites for several miRNAs, some of which were related to the IR process. Functional studies suggested that the adipose-derived exosomal lncRNA AK018453 was associated with IR and could be taken up by skeletal muscle tissue.Conclusion:The results of these analyses indicated that obesity-associated IR results in the dysregulation of exosomal lncRNA expression in mice, while also supporting the ability of the lncRNAs within these exosomes to mediate cross-talk between adipose and skeletal muscle tissue, thereby potentially shaping the pathogenesis of obesity-associated IR.
Ambulance deployment without transport - A retrospective difference analysis for the description of emergency interventions without patient transport in Bavaria
Authors: Dax Florian , Trentzsch Heiko , Lazarovici Marc , Hegenberg Kathrin , Kneißl Katharina , Hoffmann Florian , Prückner Stephan
Published: October 2022

Background:

Not all patients who call the ambulance service are subsequently transported to hospital. This study describes factors that influence patient transport rates.

Method:

This is a retrospective cross-sectional study based on data from all Integrated Dispatch Centres of the Free State of Bavaria in 2018. Included were ambulance deployments without emergency physician involvement, which were subdivided into ambulance deployments without transport (RoT) and ambulance deployments with transport (TP). Patient transport quota (PTQ) were determined for the primary reasons for deployment and for the different community types. On-scene time was compared for calls with and without patient transport. Differences were tested for statistical significance (α = 0.05) using Chi2 tests and the odds ratio (OR) was calculated to determine differences between groups.

Results:

Of 510,145 deployments, 147,621 (28.9%) could be classified as ambulance deployments without transport (RoT) and 362,524 (71.1%) as ambulance deployments with transport (TP). The lowest PTQ was found for reasons with fire brigade involvement ("fire alarm system" 0.6%, "fire with EMS" 5.4%) and "personal emergency response system active alarm" (18.6%). The highest PTQs were for "childbirth/delivery" (96.9% PTQ) and "trauma" (83.2% PTQ). A lower PTQ is observed in large cities than in smaller cities or rural communities; in the community type Large City, the odds ratio for RoT is 2.02 [95% confidence interval 1.98–2.06] referenced to Rural Community. The median on-scene time for RoT was 20.8 minutes (n = 141,052) and for TP was 16.5 minutes (n = 362,524). The shortest on-scene times for RoT were identified for the reasons "fire alarm system" (9.0 minutes) and "personal emergency response system active alarm" (10.6 minutes).

Conclusion:

This study shows that the transport quota depends on the reason for deployment and the type of municipality. Particularly low PTQs are found in fire brigade and personal emergency response system operations. The engagement times of the rescue vehicle are increased for RoT deployments. The study could not provide a rationale for this and further research is needed.
Trial registration:
This paper is part of the study "Rettungswageneinsatz ohne Transport” [“Ambulance deployment without transport”] (RoT), which was registered in the German Register of Clinical Studies under the number DRKS00017758.
Portal blood Flow following Sleeve Gastrectomy; a before- after study
Authors: Alamdari Nasser Malekpour , Salevatipour Babak , Besharat Sara , Abbasi Maryam , Taherpour Niloufar , Mirahmadi Alireza , Rashnoo Fariborz , Zeinalpour Adel , Farsi Yeganeh , Hajimirzaei Seyed Hossein , Soori Mohsen
Published: October 2022

Backgrounds: Portal Venous Thrombosis after sleeve gastrectomy can be due to changes in portal vein flow. The present study was designed to compare the portal vein flow before and after sleeve surgery using Doppler ultrasonography to investigate any changes in the type of portal vein flow after the sleeve surgery.
Methods: This study is a prospective study in which all people (n=60) referred to our hospital in Tehran from June to August 2020 for Sleeve gastrectomy surgery were evaluated. Participants’ information was collected from patients’ medical records through a researcher-made checklist. Using proper statistical tests, all statistical analyses significant at less than 0.05 were analyzed.
Results: Among 60 patients under sleeve gastrectomy, 51 (85%) were females. The mean age was 35.63 ± 9.004. Based on postoperative follow-up (3 days after sleeve gastrectomy), portal vein flow has decreased (proportion: 0.3667, 95% CI: 0.25 – 0.49 cc/min) in 22 patients (36.67%). In these patients, both the mean of portal vein flow (955.90 ± 177.88 cc/min) and the mean of portal vein diameter (10.43 ± 0.80 mm) was significantly decreased (P<0.001).
Conclusion: The complications following the sleeve surgery are rare, but considering the various reports of thrombosis after sleeve surgery, it is necessary to pursue high-risk people and keep them under consideration to prevent any complications after surgery.
Adjuvant Melatonin for Uveal Melanoma (AMUM): Protocol for a Randomized Open-label Phase III Study
Authors: Hagström Anna , Omar UG Ruba Kal , Stålhammar
Published: October 2022

Background Uveal melanoma is the most common primary intraocular tumor in adults. In Sweden, 60 to 100 patients are diagnosed with the disease each year. Almost half of the patients develop metastases, with a median survival time of 1 year once metastases are detected. The primary ocular tumor is typically treated with either enucleation or brachytherapy, and no adjuvant treatment is added. Melatonin is an indolamine hormone that has improved survival in previous trials with patients diagnosed with various cancers, including advanced cutaneous melanoma. Side effects have been mild. We aim to investigate if adjuvant treatment with melatonin for 5 years following diagnosis of non-metastasized uveal melanoma can decrease the occurrence of metastases. Methods An open-label, prospective, 5-year randomized clinical trial (RCT) will be conducted at St. Erik Eye Hospital. Patients (n = 100) diagnosed with non-metastatic uveal melanoma will be included in this trial and randomized to either treatment with adjuvant melatonin 20 mg (4 tablets of 5 mg) at 10 pm for five years, or to standard follow-up (control group). The primary outcome measurement is the number of patients that have developed metastases 5 years after randomization. The secondary outcomes are overall survival, risk of developing other cancers, overall survival after detection of metastases, and differences in the occurrence of adverse events (AE) and serious adverse events (SAE) between the groups. Discussion Melatonin has been found to positively impact our immune system, inhibit angiogenesis, stimulate apoptosis in malignant cells, and act as a potent antioxidant. Previous clinical trials have used similar doses of melatonin with positive results, particularly in advanced stages of cancer. Previous animal and human studies have found the toxicity of the hormone to be low. Considering the potential benefits and limited risks of melatonin, as well as its global availability, it may be a suitable candidate for an adjuvant treatment in patients with uveal melanoma. Trial registration Our trial protocol has been approved and registered by the Swedish Medical Products Agency on June 22, 2022 (EudraCT 2022-500307-49-00). Our trial registration number is NCT05502900 and the date of registration is August 16, 2022.
Novel development of Zinc oxide coated Carbon nanoparticles from Pineapples leaves using sol gel method for optimal adsorption of Cu 2+ and reuse in a latent fingerprint.
Authors: Fouda-Mbanga Bienvenu-Gael , Kriveshini Pillay , Tywabi-Ngeva Zikhona
Published: October 2022

This study underlines a latest approach of preparing Nitrogen carbon nanoparticles fused on zinc oxide nanoparticles nanocomposite (N-CNPs/ZnONPs nanocomposite) for the uptake of copper ions (Cu2+) from wastewater using a sol gel method and applied the metal loaded adsorbent in the latent fingerprint application. N-CNPs/ZnONPs nanocomposite proved to be a good sorbent for the optimal adsorption of Cu2+ at pH 8 and 0.05 g dosage. Langmuir isotherm best fitted the process with the maximum adsorption capacity of 285.71 mg/g that was superior to most values reported in other studies for the removal of Cu2+. At 25 oC, the adsorption was spontaneous and endothermic. Furthermore, Cu2+-N-CNPs/ZnONPs nanocomposite revealed to be sensitive and selective for latent fingerprint (LFP) identification on a variety of porous surfaces. As a result, it is an excellent identifying chemical for latent fingerprint recognition in forensic science.