bluuebunny/crossref_metadata_2025 huggingface dataset:
Microcin C7 as a Potential Antibacterial-Immunomodulatory Agent in the Postantibiotic Era: Overview of Its Bioactivity Aspects and Applications
Authors: Yang Fengjuan , Yang Feiyun , Huang Jinxiu , Yu Haitao , Qiao Shiyan
Published: July 2024

In the postantibiotic era, the pathogenicity and resistance of pathogens have increased, leading to an increase in intestinal inflammatory disease. Bacterial infections remain the leading cause of animal mortality. With increasing resistance to antibiotics, there has been a significant decrease in resistance to both inflammation and disease in animals, thus decreasing production efficiency and increasing production costs. These side effects have serious consequences and have detracted from the development of China’s pig industry. Microcin C7 (McC7) demonstrates potent antibacterial activity against a broad spectrum of pathogens, stable physicochemical properties, and low toxicity, reducing the likelihood of resistance development. Thus, McC7 has received increasing attention as a potential clinical antibacterial and immunomodulatory agent. McC7 has the potential to serve as a new generation of antibiotic substitutes; however, its commercial applications in the livestock and poultry industry have been limited. In this review, we summarize and discuss the biosynthesis, biochemical properties, structural characteristics, mechanism of action, and immune strategies of McC7. We also describe the ability of McC7 to improve intestinal health. Our aim in this study was to provide a theoretical basis for the application of McC7 as a new feed additive or new veterinary drug in the livestock and poultry breeding industry, thus providing a new strategy for alleviating resistance through feed and mitigating drug resistance. Furthermore, this review provides insight into the new functions and anti-infection mechanisms of bacteriocin peptides and proposes crucial ideas for the research, product development, and application of bacteriocin peptides in different fields, such as the food and medical industries.
Long-Term Remission with Novel Combined Immune-Targeted Treatment for Histiocytic Sarcoma Accompanied by Follicular Lymphoma: Case Report and Literature Review
Authors: Zhang Minyue , Xiao Fei , Fang Jianchen , Liu Zebing , Shen Yanying , Zhu Di , Zhang Yiwei , Hou Jian , Huang Honghui
Published: July 2024

Histiocytic sarcoma (HS) is an extremely rare but aggressive hematopoietic malignancy, and the prognosis has been reported to be rather unfavorable with a median overall survival of merely 6 months. We presented a 58-year-old female patient complaining of abdominal pain and fever, who was admitted to our institution in September 2021. Fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) scan showed enlargement of generalized multiple lymph nodes. Subsequently, laparoscopic retroperitoneal lesion biopsy and bone marrow aspiration were performed. The pathological findings indicated the diagnosis of HS concurrent with follicular lymphoma. The immunohistochemistry (IHC) staining of the tumor lesion revealed a high expression of CD38 and PD-L1 proteins. Furthermore, KRAS gene mutation was identified by means of next-generation sequencing. The patient exhibited poor treatment response to both first- and second-line cytotoxic chemotherapies. Therefore, she underwent six cycles of Daratumumab (anti-CD38 monoclonal antibody), Pazopanib (multi-target receptor tyrosine kinases inhibitor) combined with third-line chemotherapy, followed by involved-site radiotherapy and maintenance therapy with the PD-1 inhibitor Tislelizumab. Long-term partial remission was finally achieved after multi-modality treatment. Duration of remission and overall survival reached 22 and 32 months, respectively. Our case indicated that immuno-targeted treatment coupled with chemotherapy and radiotherapy might constitute a potential therapeutic option for HS.
Optimization Design and Performance Study of Wearable Thermoelectric Device Using Phase Change Material as Heat Sink
Authors: Xin Jiakai , Xu Guiying , Guo Tao , Nan Bohang
Published: July 2024

Wearable thermoelectric generators have great potential to provide power for smart electronic wearable devices and miniature sensors by harnessing the temperature difference between the human body and the environment. However, the Thomson effect, the Joule effect, and heat conduction can cause a decrease in the temperature difference across the thermoelectric generator during operation. In this paper, phase change materials (PCMs) were employed as the heat sink for the thermoelectric generator, and the COMSOL software 6.1 was utilized to simulate and optimize the power generation processes within the heat sink. The results indicated that with a PCM height of 40 mm, phase transition temperature of 293 K, latent heat of 200 kJ/kg, phase transition temperature interval of 5 K, thermal conductivity of 50 W/(m·K), isobaric heat capacity of 2000 J/(Kg·K), density of 1000 kg/m3, and convective heat transfer coefficient of 10 W/(m·K), the device can maintain a temperature difference of 18–10 K for 1930 s when the thermoelectric leg height is 1.6 mm, and 3760 s when the thermoelectric leg height is 2.7 mm. These results demonstrate the correlation between the device’s output performance and the dimensions and performance parameters of the PCM heat sink, thereby validating the feasibility of employing the PCM heat sink and the necessity for systematic investigations.
Simulation Analysis and Key Performance Index for Experimental Verification of a New Type of Press Transmission Mechanism
Authors: He Yanzhong , Luo Xiang , Wang Xingsong
Published: July 2024

In this paper, the characteristics of special stamping process requirements and the shortcomings of existing application technology are studied. Through repeated motion simulation analysis and size optimization calculation, a kind of inertia-controlled molding press is proposed to make up for this technical vacancy. This paper first describes the working principle and structure scheme of the main transmission mechanism of the inertia-controlled molding press. With the help of Adams-View x64 2013, the main transmission mechanism is simulated and analyzed from the aspects of kinematics and dynamics, and a physical prototype is made to test the key reliability indexes of the main transmission mechanism. According to the test data, the static strength, stiffness, vibration characteristics, and dynamic characteristics of the 200 t inertia-controlled molding press are evaluated, which provides a reference for the design of this kind of machine tool.
Air-Assisted Electrospinning of Dihydromyricetin-Loaded Dextran/Zein/Xylose Nanofibers and Effects of the Maillard Reaction on Fiber Properties
Authors: Ren Yupeng , An Jianhui , Tian Cheng , Shang Longchen , Tao Yexing , Deng Lingli
Published: July 2024

Dihydromyricetin (DMY) has been encapsulated in delivery systems to address the solubility limitations of DMY in water and improve its bioavailability. Air-assisted electrospinning has been used as a novel technology to load DMY. To evaluate the impact of adding DMY to dextran/zein nanofibers and understand the effects of the Maillard reaction (MR) on the physical and functional properties of DMY-loaded nanofibers, dextran/zein/xylose nanofibers with 0%, 1%, 2%, 3%, and 4% DMY were fabricated, followed by MR crosslinking. Scanning electron microscopy (SEM) observations indicated that the addition of DMY and the MR did not affect the morphology of the nanofibers. X-ray diffraction (XRD) results indicated amorphous dispersion of DMY within the nanofibers and a decreased crystalline structure within the nanofibers following the MR, which might improve their molecular flexibility. The nanofibrous film formed after the MR exhibited both increased tensile strength and elastic modulus due to hydrogen bonding within the nanofibers and increased elongation at break attributed to the increased amorphization of the structure after crosslinking. The nanofibers were also found to exhibit improved heat stability after the MR. The antioxidant activity of the nanofibers indicated a dose-dependent effect of DMY on radical scavenging activity and reducing power. The maintenance of antioxidant activity of the nanofibers after the MR suggested heat stability of DMY during heat treatment. Overall, dextran/zein nanofibers with various DMY contents exhibited tunable physical properties and effective antioxidant activities, indicating that dextran/zein nanofibers offer a successful DMY delivery system, which can be further applied as an active package.
Effects of Different pH Levels on the Structural and Functional Properties of Proteins of Phaeodactylum tricornutum
Authors: Wang Yanli , Zhu Laijing , Zhu Zhunyao , Liu Meng , Zhao Xiangzhong
Published: July 2024

Phaeodactylum tricornutum is identified by its capacity for rapid growth, reproduction, and in vitro cultivation, as well as the presence of a range of high-value active compounds, including proteins, with potential food applications. The objective of this study was to investigate the effects of pH shift treatments (pH of 3, 5, 7, 9, and 11) on the structural and functional properties of the Phaeodactylum tricornutum protein (PTP). The molecular weight of the PTP was predominantly distributed within the following ranges: below 5 kDa, 5–100 kDa, and above 100 kDa. Compared to the acidic environment, the PTP demonstrated higher solubility and greater free sulfhydryl group content in the alkaline environment. Additionally, PTP had a smaller particle size and higher thermal stability in alkaline environments. The PTP exhibited superior foaming ability (135%), emulsification activity index (3.72 m2/g), and emulsion stability index (137.71 min) in alkaline environments. The results of this investigation provide a foundation for the future development and application of the PTP in the food industry.
Theoretical Study of Copper Squarate as a Promising Adsorbent for Small Gases Pollutants
Authors: Adjal Celia , Guechtouli Nabila , Timón Vicente , Colmenero Francisco , Hammoutène Dalila
Published: July 2024

Copper squarate is a metal–organic framework with an oxo-carbonic anion organic linker and a doubly charged metal mode. Its structure features large channels that facilitate the adsorption of relatively small molecules. This study focuses on exploring the potential of adsorbing small pollutants, primarily greenhouse gases, with additional investigations conducted on larger pollutants. The objective is to comprehend the efficacy of this new material in single and multiple molecular adsorption processes using theoretical methods based on density functional theory. Furthermore, we find that the molecular adsorption energies range from 3.4 KJ∙mol−1 to 63.32 KJ∙mol−1 depending on the size and number of adsorbed molecules. An exception is noted with an unfavorable adsorption energy value of 47.94 KJ∙mol−1 for 4-nitrophenol. More importantly, we demonstrate that water exerts an inhibitory effect on the adsorption of these pollutants, distinguishing copper squarate as a rare MOF with hydrophilic properties. The Connolly surface was estimated to give a more accurate idea of the volume and surface accessibility of copper squarate. Finally, using Monte Carlo simulations, we present a study of adsorption isotherms for individual molecules and molecules mixed with water. Our results point out that copper squarate is an efficient adsorbent for small molecular pollutants and greenhouse gases.
Molecular and Phytochemical Characteristics of Flower Color and Scent Compounds in Dog Rose (Rosa canina L.)
Authors: Jariani Parisa , Shahnejat-Bushehri Ali-Akbar , Naderi Roohangiz , Zargar Meisam , Naghavi Mohammad Reza
Published: July 2024

This study delves into the chemical and genetic determinants of petal color and fragrance in Rosa canina L., a wild rose species prized for its pharmacological and cosmetic uses. Comparative analysis of white and dark pink R. canina flowers revealed that the former harbors significantly higher levels of total phenolics (TPC) and flavonoids (TFC), while the latter is distinguished by elevated total anthocyanins (TAC). Essential oils in the petals were predominantly composed of aliphatic hydrocarbons, with phenolic content chiefly constituted by flavonols and anthocyanins. Notably, gene expression analysis showed an upregulation in most genes associated with petal color and scent biosynthesis in white buds compared to dark pink open flowers. However, anthocyanin synthase (ANS) and its regulatory gene RhMYB1 exhibited comparable expression levels across both flower hues. LC-MS profiling identified Rutin, kaempferol, quercetin, and their derivatives as key flavonoid constituents, alongside cyanidin and delphinidin as the primary anthocyanin compounds. The findings suggest a potential feedback inhibition of anthocyanin biosynthesis in white flowers. These insights pave the way for the targeted enhancement of R. canina floral traits through metabolic and genetic engineering strategies.
Theoretical Design of Tellurium-Based Two-Dimensional Perovskite Photovoltaic Materials
Authors: Long Chunhong , Huang Peihao
Published: July 2024

In recent years, the photoelectric conversion efficiency of three–dimensional (3D) perovskites has seen significant improvements. However, the commercial application of 3D perovskites is hindered by stability issues and the toxicity of lead. Two–dimensional (2D) perovskites exhibit good stability but suffer from low efficiency. Designing efficient and stable lead–free 2D perovskite materials remains a crucial unsolved scientific challenge. This study, through structural prediction combined with first–principles calculations, successfully predicts a 2D perovskite, CsTeI5. Theoretical calculations indicate that this compound possesses excellent stability and a theoretical efficiency of up to 29.3%, showing promise for successful application in thin–film solar cells. This research provides a new perspective for the design of efficient and stable lead-free 2D perovskites.
A Review of Machine Learning and QSAR/QSPR Predictions for Complexes of Organic Molecules with Cyclodextrins
Authors: Boczar Dariusz , Michalska Katarzyna
Published: July 2024

Cyclodextrins are macrocyclic rings composed of glucose residues. Due to their remarkable structural properties, they can form host–guest inclusion complexes, which is why they are frequently used in the pharmaceutical, cosmetic, and food industries, as well as in environmental and analytical chemistry. This review presents the reports from 2011 to 2023 on the quantitative structure–activity/property relationship (QSAR/QSPR) approach, which is primarily employed to predict the thermodynamic stability of inclusion complexes. This article extensively discusses the significant developments related to the size of available experimental data, the available sets of descriptors, and the machine learning (ML) algorithms used, such as support vector machines, random forests, artificial neural networks, and gradient boosting. As QSAR/QPR analysis only requires molecular structures of guests and experimental values of stability constants, this approach may be particularly useful for predicting these values for complexes with randomly substituted cyclodextrins, as well as for estimating their dependence on pH. This work proposes solutions on how to effectively use this knowledge, which is especially important for researchers who will deal with this topic in the future. This review also presents other applications of ML in relation to CD complexes, including the prediction of physicochemical properties of CD complexes, the development of analytical methods based on complexation with CDs, and the optimisation of experimental conditions for the preparation of the complexes.
Recent Innovations in Footwear and the Role of Smart Footwear in Healthcare—A Survey
Authors: Rukmini Pradyumna G. , Hegde Roopa B. , Basavarajappa Bommegowda K. , Bhat Anil Kumar , Pujari Amit N. , Gargiulo Gaetano D. , Gunawardana Upul , Jan Tony , Naik Ganesh R.
Published: July 2024

Smart shoes have ushered in a new era of personalised health monitoring and assistive technologies. Smart shoes leverage technologies such as Bluetooth for data collection and wireless transmission, and incorporate features such as GPS tracking, obstacle detection, and fitness tracking. As the 2010s unfolded, the smart shoe landscape diversified and advanced rapidly, driven by sensor technology enhancements and smartphones’ ubiquity. Shoes have begun incorporating accelerometers, gyroscopes, and pressure sensors, significantly improving the accuracy of data collection and enabling functionalities such as gait analysis. The healthcare sector has recognised the potential of smart shoes, leading to innovations such as shoes designed to monitor diabetic foot ulcers, track rehabilitation progress, and detect falls among older people, thus expanding their application beyond fitness into medical monitoring. This article provides an overview of the current state of smart shoe technology, highlighting the integration of advanced sensors for health monitoring, energy harvesting, assistive features for the visually impaired, and deep learning for data analysis. This study discusses the potential of smart footwear in medical applications, particularly for patients with diabetes, and the ongoing research in this field. Current footwear challenges are also discussed, including complex construction, poor fit, comfort, and high cost.
Desenvolvimento de dispositivo automatizado para o monitoramento da altura do dossel de gramíneas forrageiras
Authors: Coelho Rigles Maia , Pinto Milena Cardoso , Pereira Nathália Aparecida Fernandes , Losqui Alberto Luiz Costa , Vieira Júnior Damião de Sousa
Published: July 2024

Em uma sociedade contemporânea altamente tecnológica, é imprescindível a formação humana em nível superior, capaz de aliar as possibilidades dessa tecnologia às necessidades de sua área de atuação. Diante desse contexto, esse artigo apresenta um trabalho desenvolvido por estudantes de bacharelado em Zootecnia e orientado por docentes de Física, cujo objetivo foi contextualizar e utilizar a prototipagem eletrônica na otimização do método de monitoramento da altura do dossel de gramíneas forrageiras. Durante o trabalho, os graduandos puderam aprender técnicas envolvendo programação, eletrônica e trabalho em equipe. A metodologia foi baseada na verificação da eficiência do sensor vl53l1x, baseado na técnica LIDAR no monitoramento da altura de pastagem, sendo para isso desenvolvido um protótipo em pequena escala para realização de leituras em altura fixa, através da plataforma Arduino. Observou-se que as características morfológicas e a arquitetura de dossel influenciam diretamente nas leituras bem como o ângulo de medida do sensor. Além disso, foram observados dificuldades devido à interferência da luz solar. Em decorrência disso, o mesmo foi substituído por um sensor ultrassônico HC-SR04, que por sua vez demonstrou o potencial de sonares no acompanhamento da variável analisada. Para validação da técnica ao propósito desejado é necessário a implementação de um sensor LIDAR diferente do vl53l1x por um modelo com melhor tolerância à interferência de luz solar. Em termos gerais, os estudantes agregaram conhecimentos básicos em Física e na aplicabilidade de recursos tecnológicos à sua aŕea de formação, demonstrando o sucesso e a importância da metodologia interdisciplinar na formação superior.
Estudo da migração para o mercado livre de energia em uma indústria alimentícia
Authors: Francisco Ricardo Bezerra , Silva Leandro Cardoso da , Silva Edson Pereira da , Bisneto Manuel Patrício da Silva , Cardoso Edgar Gonçalves
Published: July 2024

Este estudo explora a transição de uma indústria alimentícia para o mercado livre de energia, enfatizando a análise dos benefícios econômicos dessa mudança. A metodologia adotada inclui a coleta e análise de dados de consumo de energia da empresa para avaliar o impacto financeiro da migração. Os resultados indicam uma redução significativa nos custos de energia, alcançando economias de aproximadamente R$ 440.000 em nove meses. A migração permitiu não apenas a negociação de tarifas mais vantajosas, mas também promoveu a adoção de práticas de eficiência energética. O estudo conclui que a migração para o mercado livre é benéfica, possibilitando uma gestão de energia mais eficiente e sustentável para a indústria alimentícia.
مشروع قانون تعديل المادة (198) من القانون رقم (16) لسنة (1960) بشأن قانون الجزاء فيما يتعلق بالتشبه بالجنس الآخر من القانون الكويتي دراسة فقهية مقاصدية
Authors: الرشيدي وسن سعد , القحطاني سارة متلع
Published: July 2024

فكرة البحث الرئيسية تتلخص في التعليق على مشروع قانون تعديل المادة (198) من القانون الكويتي رقم (16) لسنة (1960) بشأن قانون الجزاء فيما يتعلق بالتشبه بالجنس الآخر، وتكمن أهمية البحث في أن المادة (198) والتي نصت على تجريم التشبه بالجنس الآخر، قد صدر حكم المحكمة الدستورية بعدم دستورية عبارة (أو تشبه بالجنس الآخر بأي صورة من الصور) من المادة المذكورة -مما ترك فراغًا تشريعيًّا- قام على أثره مجموعة من نواب مجلس الأمة الكويتي باقتراح تعديل للمادة، ومن هذا المنطلق جاءت هذه الدراسة للتعليق على حكم المحكمة الدستورية، وتنقيح نص القانون المقترح. وتتمثل إشكالية البحث في الإجابة عن الإشكالات القانونية والفقهية فيما يخص حكم المحكمة الدستورية، وهل من الممكن إضافة بعض الفقرات على القانون المقترح بما يتوافق مع المقاصد الشرعية ويخدم أمن المجتمع الكويتي؟ ويهدف هذا البحث إلى بيان معنى التشبه بالجنس الآخر، وضوابطه، وحكم التشبه بالجنس الآخر وعقوبته، بالإضافة إلى توضيح الإشكالات القانونية والفقهية فيما يخص حكم المحكمة الدستورية، والتعليق على نص مشروع القانون المقترح. واتُّبِع في ذلك المنهج الوصفي، والمنهج النقدي التحليلي، ومن أبرز النتائج التي خلص إليها البحث: أن الإشكالات القانونية التي تم استناد حكم المحكمة الدستورية إليها في إبطال المادة (198) كانت لتزول إذا ما تم اتباع قواعد التفسير المعتبرة لنصوص الدستور، ودون الحاجة لإلغاء دستوريتها، بالإضافة إلى تهذيب نص مشروع القانون المقترح بما يتوافق مع الرؤية الفقهية والاجتهاد المقاصدي. لذلك يرى البحث: أن على السلطة التشريعية المسارعة بتشريع القانون الجديد المجَرِّم للتشبه بالجنس الآخر آخذًا بعين الاعتبار الملاحظات الشرعية الواردة في الدراسة.
Advances in Fiber-Based Wearable Sensors with Machine Learning
Authors: Luo Ziwang , Xu Jiaming , Zhou Xuhui , Wang Zhixun , Liu Yanting , Wang Shuai , Yuan Shixing , Zhang Haozhe , He Bing , Xin Jiwu , Wang Haoran , Zhang Weina , Lin Zhiping , Wei Lei
Published: July 2024

Fiber sensors, with their high sensitivity and flexibility, have contributed to the integration of wearable technologies into everyday clothing, enabling both comfortability and efficient data collection. Meanwhile, the rapid advancements in machine learning have substantially boosted the capability of wearable technology to process intricate information collected from the human body and environment. This work offers a comprehensive review of wearable devices that utilize both fiber sensors and machine learning. Various fiber sensors are discussed based on their working principles and dimensions, and an overview of the machine learning algorithms that have been applied with these fiber sensors is presented. Additionally, the advantages, limitations, and concerns of different approaches are highlighted, paving the way for the future development of intelligent wearable devices and systems.
QoS-Aware Precoding for Dual-Polarized Downlink Massive MIMO LEO Satellite Communications
Authors: Huang Yan , You Li , Wang Kezhi , Gao Xiqi
Published: July 2024

Low Earth Orbit (LEO) satellite communications (SATCOM) are important for wireless networks and offer better global wireless access services than higher altitude SATCOM options. SATCOM performance is affected by the number of antennas, which is usually constrained by the satellite space. In this paper, the application of dual-polarized technology is considered to assist LEO SATCOM. Compared with single-polarized antennas, dual-polarized antennas utilize two different polarization orientations to transmit and receive data. This can improve the quality of service (QoS) performance, as it allows for twice the amount of data to be transmitted over the same time–frequency resources. Specifically, we characterize the dual-polarized channel in massive multiple-input multiple-output (MIMO) LEO SATCOM and investigate the precoding design for enhancing the system performance. In particular, a precoding optimization problem is formulated, which aims to jointly optimize the system throughput and the QoS performance. We divide the problem into two stages and develop novel algorithms for each stage to obtain the precoding vectors. The numerical results demonstrate that the dual-polarized technology can improve the system throughput, and the proposed algorithm leads to a higher percentage of users achieving their QoS requirements compared to conventional approaches.
A cognitive contrast of Polish and English proverbs with dog components
Authors: Kochman-Haładyj Bożena
Published: July 2024

The article deals with the application of dog metaphorical concepts embodied in the proverbs of Polish and English linguo-cultures. By conducting a cross-cultural cognitive investigation of the main meaning encoded in the selected proverbs the aim of the study is directed at examining the universality of proverbs' content and the socio-cultural influences upon the use of dogs in proverbial items. Furthermore, there are shown some mechanisms affecting the conceptualization of human behaviour perceived in terms of animal behavior.
SYMBOLIC METAMETAPHORS IN BORGES' "THE HOUSE OF ASTERION"
Authors: Kravchenko Nataliia , Markova Yuliia
Published: July 2024

The paper examines metametaphors in Borges' "The House of Asterion", focusing on reconstructing symbolic metametaphors and derivative metaphorical constructs within a postmodernist and existentialist framework. It highlights the role of metaphorical core and periphery in encoding the narrative-semiotic structure. The study reveals that metametaphors serve as codes for interpreting and integrating images and meanings, aligning with symbolic metaphorical constants in postmodern and existential-philosophical texts.
WHAT DOES LOONG (龙) MEAN TO THE CHINESE PEOPLE? A CULTURAL COGNITIVE LINGUISTIC PERSPECTIVE
Authors: Wen Xu , Chen Chuanhong
Published: July 2024

This present study discusses the mythology of Loong in Chinese culture, analyzes the cultural metaphors of Loong, and elaborates on the cultural values of Loong. Through the discussion, it can be seen that the Chinese cultural values of Loong have a profound influence on cultural conceptualizations of Loong, not only manifested in language but also in many other aspects.
In Search of Institutional Servingness: Institutional Characteristics and Outcomes of Minority-Serving Institutions
Authors: Mac Jacqueline , Bauman Kandi , Bussey Karen , Gokpinar-Shelton Esen , Schellpfeffer Shane , McLaren Turner Claudine
Published: July 2024

Minority-serving institutions (MSIs) are considered models of excellence to support underrepresented racial and ethnic students; however, multiple definitions of MSIs complicate the consumption and production of research on these critical institutions. The U.S. Department of Education (ED) uses set criteria to define MSIs, based primarily on enrollment. However, scholars and practitioners have argued for considering factors beyond enrollment, such as equitable student outcomes and institutional markers of a serving culture. This study used descriptive analyses of IPEDS data to explore the extent to which MSIs served their target population. We use national weighted averages to report results on each MSI category compared to all other institutions. We found that MSIs enrolled higher percentages of MSI-aligned students and employed more-significant percentages of MSI-aligned instructional staff. Most MSIs generally retained higher percentages of MSI-aligned students. Most MSIs showed higher completion proportions, though nearly all MSI categories had lower graduation rates among MSI-aligned students. Some MSIs provided institutional aid to higher proportions of students; others provided lower proportions. Findings confirm that enrollment alone cannot be a proxy for servingness. We encourage researchers, practitioners, and government agencies to use more-holistic definitions. We make recommendations for government agencies to remove burdens to researching MSIs.
Convergence Issues for Disability Measures at Public 2-Year Institutions
Authors: Zilvinskis John
Published: July 2024

The purpose of this study is to demonstrate how triangulating responses from the Community College Survey of Student Engagement (CCSSE) with information from the federal Integrated Postsecondary Education Data System (IPEDS) exposes data incongruency, specifically when considering the population of students with disabilities at 2-year institutions. Data from 503 CCSSE institutions were aggregated to calculate the average proportion of respondents who use services for students with disabilities, and then were compared to the percent of undergraduates who are formally registered with the institution’s Office of Disability Services, as reported to IPEDS. Pearson correlation coefficients indicated statistically significant relationships, that are yet moderate in strength, between these measures of disability services use (.274 < r < .331), compared to strong correlations of measures of gender, race, and enrollment (.618 < r < .955). These effects indicate an incongruency between measures of disability, compared with other aspects of demography. Accounting for coverage of survey data using a multiple linear regression model did not improve convergence. These findings have implications both for institutional staff to triangulate their data to see if there is a need to review reporting procedures, and for higher education scholars who work with these data to understand the proportion of disabled students in the 2-year sector.
Socio-economic determinants of development in reference to the change in population size in Central and Eastern Europe between 2008 and 2019
Authors: Truskolaski Tadeusz , Bugowski Łukasz
Published: July 2024

For most regions of Central and Eastern Europe there has been a noticeable decline in population in recent years. The purpose of this article is to analyse the level of economic and social indicators as well as changes in population size between 2008 and 2019 in the regions of Central and Eastern Europe. In particular, the article attempts to answer the question of how the change in selected economic and social indicators impacts the change in population size. The answer to the above question will be provided with the use of the ratio analysis and thesoft model. The research results show that the two causes of changes in population size (natural causes and migrations) are significantly affected by a group of social indicators, even though—with regard to migration—the significance of economic indicators is increasing and the difference between the former and the latter is not substantial. Consequently, in response to the depopulation process, more attention should be paid to the social dimension of development. In other words, creating proper conditions for personal and professional activity may be more important than using financial instruments.
Sofosbuvir-based Antiviral Treatment in Patients with HCV and Chronic Kidney Disease
Authors: Козаченко М.Г. , Литвинчук Д.В. , Карпов И.А. , Данилов Д.Е. , Захарченко Т.С. , Карабань А.А.
Published: July 2024

Введение. Противовирусное лечение хронического гепатита С имеет важное значение для системы здравоохранения. Большинство схем лечения включают противовирусный препарат софосбувир, по применению которого у пациентов со сниженной функцией почек длительное время имелись ограничения. Цель. Оценить эффективность и безопасность противовирусного лечения ВГС-инфекции препаратами прямого действия с включением софосбувира у пациентов с хронической болезнью почек. Материалы и методы. В исследование включено 116 пациентов, у которых проводилось противовирусное лечение гепатита С на базе УЗ «ГКИБ» г. Минска в период с 2019 по 2023 г., в том числе 16 пациентов с хронической болезнью почек и 100 пациентов без хронической болезни почек. Использовались схемы: софосбувир + даклатасвир, софосбувир/велпатасвир, софосбувир/ледипасвир. Результаты. Частота достижения устойчивого вирусологического ответа у пациентов с хронической ВГС-инфекцией и хронической болезнью почек составила 100% (15/15) как через 12 недель, так и через 24 недели после завершения противовирусного лечения и была сопоставима с эффективностью лечения у пациентов без почечной патологии. Ни у одного из пациентов с хронической болезнью почек как в процессе противовирусного лечения хронической ВГС-инфекции, так и после его завершения не отмечалось статистически значимых изменений уровня креатинина и мочевины по сравнению с пациентами без хронической патологии почек. Заключение. Применение софосбувирсодержащих схем противовирусного лечения хронической ВГС-инфекции с хронической болезнью почек, включая пациентов на программном гемодиализе, характеризуется высокой эффективностью и безопасностью.

Introduction. Access to the antiviral treatment for chronic hepatitis C is essential for public health. Most antiviral regimens include sofosbuvir, which has been restricted for a long time in patients with renal insufficiency. Purpose of the study. To evaluate the efficacy and safety of HCV treatment with sofosbuvir-based antiviral regimens in patients with chronic kidney disease. Materials and methods. The study included 116 patients with antiviral treatment for hepatitis C in Minsk City Hospital for Infectious Diseases from 2019 to 2023, including 16 patients with chronic kidney disease and 100 patients without chronic kidney disease. The following regimens were used: sofosbuvir + daclatasvir, sofosbuvir/velpatasvir, sofosbuvir/ledipasvir. Results. All patients with chronic HCV infection and chronic kidney disease (15/15; 100%) achieved sustained virologic response both at 12 weeks and 24 weeks. Treatment results were comparable to those of patients without renal pathology. Both during and after antiviral treatment, none of the patients with chronic kidney disease had statistically significant changes in creatinine and urea levels. Sofosbuvir-based regimens are effective and safe in patients with chronic HCV infection and chronic kidney disease, including patients on hemodialysis.
RESPUESTA DE GRUPOS DE MAIZ DE DIFERENTE PRECOCIDAD A ETAPAS DE SEQUIA CONTROLADA
Authors: Martín del Campo-Valle Salvador , Luna-Flores Maximino
Published: July 2024

Nueve variedades de maíz (Zea mays L.)  de temporal, clasificadas en tres grupos de precocidad con 3 variedades por grupo, fueron sometidas a cuatro períodos únicos de sequía en las siguientes cuatro etapas fenológicas: de emergencia a 30 días, de 30 a 60 días, de 60 a 90 días y de 90 a 120 días después de la siembra. Cada etapa de sequía consistió en suspender el riego por aproximadamente 30 días, excepto en los tratamientos control los cuales se mantuvieron con humedad edáfica aprovechable durante todo el ciclo. Se observaron diferencias altamente significativas entre los efectos debidos a las etapas de sequía, a la precocidad y a las variedades dentro de grupos, pero las interacciones entre las etapas de sequía y grado de precocidad y de éstas con variedades no fueron significativas. Las correlaciones fenotípicas entre días a floración, rendimiento de grano y biológico, índice de cosecha y otros ocho caracteres fueron positivas y altamente significativas. No hubo correlación entre los índices de área foliar y de cosecha.
INFLUENCIA DE LA PODA EN EL CRECIMIENTO DEL FRUTO DEL DURAZNERO BAJO RIEGO Y TEMPORAL
Authors: Zegbe Domínguez Jorge A. , Pérez Barraza M. Hilda , Chan Castañeda José Luis
Published: July 2024

El rendimiento unitario de durazno (Prunus persica. L.) en Jerez, Zac. está limitado principalmen­te por un manejo deficiente del árbol. En esta re­gión se detectó que sólo 29 y 48% de los producto­res en áreas de riego y de temporal, respectivamen­te.conocen los beneficios de la poda. Con la fina­lidad de determinar el impacto de la poda y del am­biente sobre el crecimiento de fruto, en 1985 se es tudiaron en riego y temporal, los efectos del corte en la rama mixta (CRH; O, 25 y 50%), la el iminacion de chifones y bouquets (CB), y la época de poda (EP; en invierno o primavera). Se tomaron cinco frutos al azar de la parte media y alrededor del árbol, en cada uno de 11 muestreos. Las variables de respues ta que se midieron fueron: peso de fruto (PF), diámetro ecuatorial (DE) y diámetro polar (DP). Los resultados indicaron que la interacción de 25% CRH, sin CB con poda en invierno, favoreció significati­vamente a la ganancia en PF en riego. En temporal la mejor interacción fue 50% CRM, sin CB, con poda en invierno.
NEGRO ZACATECAS: VARIEDAD DE FRIJOL PARA SIEMBRAS DE RIEGO EN EL ALTIPLANO DE ZACATECAS
Authors: Alvarado Arroyo David
Published: July 2024

En 1976 se cosecharon casi 96 000 ha de frijol producido bajo condiciones de riego en el altiplano de Zacatecas, con un rendimiento promedio de 2100 kg/ha y una producción global de 106 mil toneladas, que representaron el 35% de la producción total del estado. Los principales problemas que limitan la producción de frijol bajo esas condiciones son: la decoloración y manchado del grano por la presencia de lluvias en la etapa de madurez; y en siembras tardías (15 de ccayo al 15 de junio) la presencia de en­fermedades como roya o chahuixtle {Uromices plaseolicola (Roben) Wint.}, tizón de halo {Pseudomonas phaseolicola (Burk) Dows.} y tizón común {Xanthomonas, phaseoli (E. F. Sm) Dows.} que pueden reducir el rendimiento de las variedades susceptibles hasta en 80%.
ENFOQUE SISTEMICO DE LA FISIOTECNIA Y LOS DETERMINANTES DE SU CURRICULA
Authors: Aguillón-Galicia Apolinar , Ibarra-Martínez José
Published: July 2024

Los cursos de Fisiotecnia de la Facultad de Agronomía de la Universidad Autonóma de Nuevo León (FAUANL) se iniciaron en1980 -semestre primavera- y en 1981 -semestre otoño- para los niveles de postgrado y licenciatura, respectivamente. A nivel de licenciatura se ofrece como un curso optativo, comprendido dentro de un paquete que abarca Fisiología Vegetal Avanzada-Fisiotecnia-Genotecnia, que se imparte en el 8o semestre de la Especialidad de Fitotecnia de la Carrera de Ingeniero Agrónomo; en la Maestría de Producción Agrícola es un curso formal. A la fecha, han cursado un total de 167 alumnos a nivel de licenciatura y 59 a nivel de postgrado, los cuales se muestran en el Cuadro 1. La Institución cuenta con un soporte físico para realizar las prácticas que se requieren en los cursos, como son: campos experimentales (Marín, Escobedo, Aramberri, Anáhuac), laboratorios (Fisiología Vegetal, Suelos, Genética, Botánica, etc.) los cuales están equipados con instrumental para realizar algunas mediciones propias de los temas impartidos (determinador de área foliar, bomba de presión, determinador de energía radiante), Biblioteca, Invernadero, Banco de Germoplasma y Centro de Cómputo. Estos recursos se han reflejado también en una serie de trabajos experimentales y tesis, en ambos niveles de enseñanza. Lo anterior es una visión panorámica de la interacción institución cursos de Fisiotecnia que se da en la FAUANL.
LA ENSEÑANZA DE LA FISIOTECNIA EN EL COLEGIO SUPERIOR AGROPECUARIO DEL ESTADO DE GUERRERO
Authors: Aguilar-Mariscal Immer
Published: July 2024

El curso teórico práctico de Fisiotecnia se ha impartido de manera optativa a nivel de licenciatura en el 8o. semestre de laEspecialidad de Fitotecnia en tres ocasiones: 1986, 1987 y 1989. El número de estudiantes que tomaron el curso fue aproximadamente de 15 en cada ocasión. El profesor responsable ha sido el autor de este trabajo, quien tiene un doctorado en Fisiotecnia de la Universidad de Guelph, Canadá. El contenido del curso ha sufrido varias modificaciones sobre todo por la falta de instrumentación y de facilidades en el laboratorio. Esto se ha subsanado en parte visitando el programa de Fisiología de Maíz del CIMMYT, en Tlaltizapán, Mor. La disponibilidad de bibliografía es una limitante ya que no se reciben revistas especializadas, además de que no se cuenta con un libro en español. Proporcionar al estudiante de licenciatura artículos en inglés, realmente no soluciona el problema, por lo que es urgente preparar apuntes impresos para este curso. Existen muchas facilidades de campo para realizar las prácticas, ya que el campo experimental está junto a las aulas; además, se cuenta con riego por gravedad y como no se presentan riesgos de heladas es posible tener dos ciclos de cultivo, o establecer estudios de fechas de siembra en cualquier época del año. Por otra parte, debido a que se tiene un invierno seco, es posible establecer ensayos de sequía en el ciclo de noviembre-marzo. Estas condiciones permiten el establecimiento de diferentes cultivos sin grandes problemas. La principal limitante es la falta de instrumentos, y aunque un invernadero está casi terminado, hace falta el equipo de laboratorio. Durante el presente año se está revisando el Plan de Estudios en el CSAEG, y afortunadamente se ha contemplado que Fisiotecnia pase de curso optativo a curso obligatorio curricular para la especialidad de Fitotecnia en el noveno semestre. Su implementación se espera a partir de 1992.
LA INVESTIGACION FISIOTECNICA EN LA UNIVERSIDAD AUTONOMA AGRARIA ''ANTONIO NARRO''
Authors: Oyervides-García Arnoldo , Borrego-Escalante Fernando
Published: July 2024

Los estudios fisiotécnicos conducidos en la Universidad Autonóma Agraria "Antonio Narro" (UAAAN) se han dirigido a la búsqueda de una mayor adaptabilidad del rendimiento de las plantas. Lo anterior, de acuerdo a la diversidad y características ambientales de la región en que está enclavada la UAAAN y su área de influencia, así como a la ecología de aquellas zonas con las que esta universidad mantiene relación. Las investigaciones están enfocadas a la búsqueda de soluciones a problemas agrícolas importantes en el entorno con que se vincula la UAAAN y a la vez, representan en muchos casos un apoyo a la enseñanza al constituir trabajos de tesis, tanto de licenciatura como de postgrado, lo que permite incorporar nuevos criterios y metodologías. De acuerdo con las tendencias desarrolladas, se pueden distinguir tres grupos de trabajos: los de parámetros de estabilidad, los de parámetros fisiotécnicos y los vinculados con la resistencia a factores adversos. En este escrito, se presenta sólo parte de los trabajos desarrollados en esos temas principales.
LA INVESTIGACION FISIOTECNICA DE OLEAGINOSAS EN MEXICO
Authors: Sánchez-Domínguez Samuel
Published: July 2024

La Fisiotecnia es una disciplina integradora de la planta, el ambiente y sus interacciones. Su propósito es definir nuevos criterios y estrategias que permitan lograr mayor eficiencia, tanto de los programas de fitomejoramiento genético, como de los procesos de producción de los cultivos agrícolas. Se ha señalado, asimismo, que la enseñanza de la Fisiotecnia se inició en México en el Colegio de Postgraduados en 1969 y posteriormente se extendió a la Escuela Nacional de Agricultura (hoy UACH) en 1970-1971 y en otras instituciones como la Universidad Autónoma Agraria Antonio Narro, Universidad de Nuevo León y Escuelas de Agricultura de otras Universidades en años posteriores. El objetivo de este trabajo fue hacer una revisión sobre la investigación de oleaginosas en México y elucidar el impacto que ha tenido la Fisiotecnia en los enfoques de investigación en dicho grupo de plantas.
RELACIONES FUENTE-DEMANDA EN FRIJOL. l. EFECTO DE LA REMOCION FOLIAR SOBRE LOS COMPONENTES DEL RENDIMIENTO
Authors: Escalante-Estrada J. Alberto , Martínez-Villegas Enrique , Rodríguez-González María Teresa , Kohashi-Shibata Josue
Published: July 2024

El tamaño de la fuente de fotosintatos (área foliar) puede ser un factor limitante del rendimiento en frijol común. El objetivo del presente trabajo fue evaluar el efecto de la remoción foliar sobre el rendimiento y sus componentes en frijol. Se realizaron experimentos de invernadero (I) y de campo (II) en Iguala, Gro. (1986) y Chapingo, Méx. (1987), respectivamente. Se utilizó la variedad Michoacán 12-A-3 de hábito indeterminado arbustivo. Los tratamientos de remoción foliar se aplicaron al inicio de la floración. En el experimento I, se eliminaron 1 ó 2 foliolos laterales o el total de las hojas localizadas en los estratos inferior, medio y superior de la planta. En el experimento II, se eliminaron los 2 foliolos laterales en toda la planta en la primera o segunda mitad de la floración. El testigo en ambos ensayos fueron plantas intactas. Las plantas con remoción de 66% en cualquier etapa del periodo de floración y la remoción de todas las hojas de cualquier estrato mostraron un número de vainas, semillas y rendimiento significativamente menor que la remoción de uno de los folio los y el testigo intacto. Por otra parte, la remoción de todas las hojas redujo el rendimiento en un 95%. Esto sugiere que los peciolos, tallos y pericarpios, sólo proporcionaron los fotosintatos para obtener un rendimiento equivalente al 5% del testigo.
EFECTO DE GENERACIONES AVANZADAS EN LA PRODUCCION DE DIFERENTES TIPOS DE HIBRIDOS DE MAIZ
Authors: Valdivia-Bernal Roberto , Vidal-Martínez Victor-Antonio
Published: July 2024

El creciente costo en la semilla de maíz, ha obligado a los productora de esta especie, a utilizar semilla de generaciones avanzadas, sin conocer la magnitud del decremento en rendimiento en los actuales híbridos. El objetivo de este estudio fue conocer elefecto en las generaciones avanzadas en diferentes tipos de híbridos de maíz actuales, al comparar las F1 con sus generaciones F2 y F3. Los tipos de híbridos incluidos fueron: cruzas simples, trilineales, dobles e intervarietales. La evaluación se realizó en 1992 entres regiones temporaleras del estado de Nayarit, México, a una altura entre 50 a 1000 msnm, bajo buenas condiciones de temporal, encontrandose una reducción media en rendimiento del 45.3% en la F2 y de 31.5% en la F3, en comparación con la F1. Los híbridos con mayor reducción fueron los simples con un 50.5% en la F2 y los de menor los intervarietales con un 39.1%. Los híbridos trilineales y dobles decrecieron su rendimiento en 47.3 y 43.7%. respectivamente. El efecto negativo de las generaciones avanzadas también fue observado en otras importantes características agronómicas, tales como número de días a floración, acame, pudrición de mazorcas y vigor en altura de planta. Se concluye que las generaciones avanzadas tuvieron un efecto negativo importante sobre el rendimiento y otras características agronómicas y por lo tanto no se recomienda su uso a los productores; en casos específicos se aconsejaría el uso de la F2 en híbridos con mayor número de progenitores.
ESTIMACION DE LA VARIANZA AMBIENTAL INTRAPARCELAR EN EL DISEÑO I DE CAROLINA DEL NORTE
Authors: Sahagún-Castellanos Jaime
Published: July 2024

La variación de origen ambiental que se produce entre las plantas de una misma parcela es de importancia teórica y aplicada en el mejoramiento genético de los cultivos. El problema de contar con un estimador de la varianza asociada a este tipo de variabilidad no ha sido totalmente resuelto puesto que de los estimadores existentes unos se basan en materiales genéticos y/o condiciones diferentes de las que se tienen en un programa de mejoramiento particular, en tanto que otros que si bien no adolecen de este problema no han sido caracterizados en términos de sus bondades como estimadores. En este estudio, utilizando el diseño I de Carolina del Norte, mediante la solución de un sistema de ecuaciones entre cuadrados medios y sus valores esperados, éstos en términos de varianzas aditiva, de dominancia y de variación ínter e intraparcelar, se identificó un estimador de la varianza ambiental intraparcelar que no tiene los problemas antes mencionados. Adicionalmente, se determinó la varianza de este estimador y la manera de estimarla.