bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolic stress levels influence the ability of the myelin transcription factors to regulate b-cell identity and survival
Authors: Tong Xin , Yagan Mahircan , Hu Ruiying , Nevills Simone , D. Stevenson Teri , W. Stein Roland , N. Balamurugan Appakalai , Gu Guoqiang
Published: July 2024

Abstract

A hallmark of type 2 diabetes (T2D) is endocrine islet b-cell failure, which can occur via cell dysfunction, loss-of-identity, and/or death. How each is induced remains largely unknown. Here, we use mouse b-cells that are deficient for Myelin transcription factors (Myt TFs, including Myt1, 2, and 3) to address this question. We have reported that inactivating all three Myt genes in pancreatic progenitor cells (MytPancD) causes b-cell failure and late onset diabetes in mice. Their lower expression in human b-cells is correlated with b-cell dysfunction and SNPs in MYT2 and MYT3 are associated in higher risk of T2D. We now show that these Myt TF-deficient postnatal b-cells also de-differentiate by reactivating several progenitor markers. Intriguingly, mosaic Myt TF inactivation in only a portion of islet b-cells does not results in overt diabetes, but this creates a condition where Myt TF-deficient b-cells stay alive while activating several markers of Ppy-expressing islet cells. By transplanting MytPancD islets into the anterior eye chambers of immune-compromised mice, we directly show that glycemic and obesity-related conditions influence cell fate, with euglycemia inducing several Ppy+ cell markers while hyperglycemia and insulin resistance inducing additional cell death. These findings suggest that the observed b-cell defects in T2D depend on not only their inherent genetic/epigenetic defects, but also the metabolic load.

Highlights:

· Myt TF-deficient b-cells dedifferentiate under euglycemia and hyperglycemia.

· Myt TF-deficient b-cells activate markers of Ppy-expressing cells at euglycemia.

· Myt TF-deficient b-cells die at hyperglycemia.

· Myt TF-deficient b-cells gain several Ppy-cell features under obesity-induction.
Estrategias de Reducción de costos en el proceso de elaboración de prendas de vestir en confecciones Yoly
Authors: Pastuña Cuchipe María Bertha ,   Universidad Técnica de Cotopaxi, Torres Briones Rosa Marjorie ,   Universidad Técnica de Cotopaxi
Published: July 2024

Este estudio se centró en identificar y proponer estrategias efectivas para la reducción de costos en el proceso de elaboración de prendas de vestir en Confecciones Yoly, una microempresa ubicada en Latacunga, Ecuador. Se realizó un análisis exhaustivo de la estructura de costos, la productividad y la calidad de los productos. Los resultados revelaron que la materia prima representaba el 55% del costo total de producción, seguida por la mano de obra directa (30%) y los costos indirectos de fabricación (15%). Se identificaron variaciones significativas en la productividad según el tipo de prenda y un desperdicio de tela del 12%. El análisis de devoluciones mostró que los defectos de costura eran la principal causa de insatisfacción del cliente. Basándose en estos hallazgos, se propusieron estrategias enfocadas en la optimización del uso de materia prima, la mejora de la productividad y la calidad, la implementación de un sistema de control de costos más riguroso, la adopción de tecnologías más eficientes y la gestión eficiente de la cadena de suministro. Se concluyó que la implementación de estas estrategias no solo era viable, sino necesaria para mejorar la competitividad de Confecciones Yoly en el mercado local.
On Some Acanthocephalans from Wildlife in Peru, with the Designation of Neoechinorhynchus (Neoechinorhynchus) cylindratus peruensis n. subsp. and Special Notes on the Status of “Polymorphus pacificus” sensu Karl, 1967
Authors: Amin Omar M , Peña César , Castro Teresa , Rubtsova Nataliya
Published: July 2024

Cystacanths and adults of 8 valid species of acanthocephalans in 3 classes that we collected from various species of wildlife in Peru over the last few years are reported. Notes on each species are supplemented by light microscope images giving new perspectives even though some have been previously published using line drawings or SEM images. The presented images are novel and original for each species and enhance some of the former depictions of species that may have been previously published. This presentation includes a treatment of the cystacanth of a moniliformid species, Moniliformis moniliformis (Bremser, 1811) Travassos, 1915 (Class Archiacanthocephala) from Rattus rattus (Linn.) in Lima, Peru. A new form of Neoechinorhynchus (Neoechinorhynchus) cylindratus (Van Cleave, 1913) Van Cleave, 1919 (Class Eoacanthocephala) different from the usual North American form collected from the mosquitofish Gambusia affinis (Baird & Girard) in Pantanos de Villa Wildlife refuge is designated as a new subspecies: Neoechinorhynchus (Neoechinorhynchus) cylindratus peruensis n. subsp. Species in 3 families of Class Palaeacanthocephala, Echinorhynchidae, Illiosentidae, and Polymorphidae are reported. Pseudoacanthocephalus lutzi (Hamann, 1891) (Echinorhynchidae) was found in the coastal toad Chaunus limensis Werner off Lima. Illiosentis furcatus Van Cleave & Lincicome 1939 (Illiosentidae) is reported from the Lorna drum Sciaena deliciosa Tschudi in La Punta. The following species in Polymorphidae are also reported. Cystacanths of Polymorphus spindlatus Amin & Heckmann, 1991 in 4 species of killifish Orestias in Lake Titicaca and in the Nile Tilapia Oreochromis niloticus Linn. in Villa swamps. Adult P. spindlatus were described from the black-crowned night heron at Puno Bay, Lake Titicaca. Cystacanths of Profilicollis altmani (Perry, 1942) Van Cleave, 1947 were described from the Pacific sand crab Emerita analoga (Stimpson) in Chorrillos, Lima and the adults from Belcher’s gull Larus belcheri (Vigors) in Ancȯn, Lima. The cystacanths of Neoandracantha peruensis Amin & Heckmann, 2017 were described from the ghost crab Ocypod gaudichaudii Milne-Edwards & Lucas from the Pacific coast off Lima. The questionable validity of “Polymorphus (=Profilicollis) pacificus” sensu Karl, 1967 is discussed and that species appears to be an extreme variant of P. altmani.
Pet Food: A New Food Item for Rhinella diptycha (Cope, 1862) (Anura: Bufonidae) in Brazil
Authors: Sousa Bruno Alves de , RA Benício , MG Fonseca
Published: July 2024

Rhinella diptycha (Cope, 1862) is a large anuran from the Bufonidae family, widely distributed in Brazil, occurring in open natural areas and urbanized regions. Its diet is mainly composed of insects, but it is known as a generalist species that consumes any available food resources. In this case report, we occasionally recorded individuals of Rhinella diptycha (in italics) (juveniles and adults) in two different regions of Brazil feeding on pet food on the ground. After observation, a female Rhinella diptycha (in italics) was collected and taken to the Laboratory of Herpetology and Parasitology of Wild Animals for diet analysis. Thirty-two prey items were identified in its stomach, in which “pet food” was the category with the highest volume (V = 55.1%) followed by Caribidae (V = 34.8%) and Formicidae (9.8%). Pet food was also the most representative item (N = 62.5%) followed by Formicidae (N = 34.3%) and Caribidae (3.1%). This is the first record in Brazil of an amphibian eating pet food. The results may be related to the urban environment, where they were recorded, as well as the presence of domestic animals in the environment. Here, we describe the unusual diet of this species, reinforcing its opportunistic nature.
The Littoral Distribution of Corals and their Relationship of Zooxanthellae Algae
Authors: Zamponi Mauricio O
Published: July 2024

There is a relationship between corals and Zooxanthellae algae very interesting because between both group there is an interchange of energy beneficious both of them and the presence of algae limits distribution of corals. This relationship is obligatory and without algae the life of corals go to the end (whitening), so this relationship is fundamental for both group because presence of each one is necesary for other.
Atmospheric Pressure and its Impact on COVID-19 Cases in Villa Clara, Cuba
Authors: Duarte Rigoberto Fimia , RR Osés , PR Vogt , GAF Osés , LD del Valle
Published: July 2024

There are a large number of natural and even social phenomena in nature, whose occurrences, evolution and final result depend on several independent variables. Even though all these variables intervene in the phenomenon, some are more important than others and even the interrelation between them plays a very important role. The intervention of several independent variables makes the prediction of the occurrence of a natural phenomenon difficult to quantify. Predictive techniques have been developed both in the study of natural phenomena and in social phenomena, each with its scope and limitations.
IMPLEMENTASI PERPUSTAKAAN SEKOLAH SEBAGAI SUMBER BELAJAR DALAM MENINGKATKAN PRESTASI BELAJAR SISWA
Authors: Kamulyan Mulyadi Sri , Primasari Febriana
Published: July 2024

The utilization existence of the library as a resource center for students in elementary school is a necessity that needs to be examined. Although the school does not have the personnel in charge of taking care of a special library, but it can be handled by a desig- nated teacher under the control of the principal to optimize he library utilization. The effectiveness of implementation will have an impact on the growth of like reading in the school library for students on one hand also creativity of teachers in using library as a learning resource for certain theme, so that students want to come or use to the school library. There is a prediction that the utilization of school library is able to increase the student achievement.
Pengukuran Elevasi Kawasan dan Penyelidikan Titik Genangan pada Kawasan Perumahan Nogotirto Elok II, Sleman, Yogyakarta
Authors: Nectaria Putri Pramesti  , Agustina Kiky Anggraini  , Christin Sri Hastuti  , Martinus Revano Bagus Pramudita
Published: July 2024

Pengabdian dilakukan pada kawasan Perumahan Nogotirto Elok II. Kawasan perumahan ini merupakan salah satu kawasan dengan kepadatan rumah yang cukup tinggi sehingga area resapan sangat rendah. Sistem drainase yang ada bertipe combined sewer system di mana air hujan dan air limbah dari dapur (grey water) dialirkan pada saluran yang sama. Kawasan perumahan ini tidak termasuk dalam area rentan banjir, namun pada musim penghujan, sering terjadi genangan yang cukup dalam. Pengabdian ini fokus pada pengukuran elevasi lahan Perumahan Nogotirto Elok II, pemodelan kawasan untuk mengetahui potensi titik genangan, dan usulan solusi yang dapat diterapkan. Pengukuran elevasi dilakukan menggunakan GPS Geodetik. Pemodelan dilakukan dengan piranti lunak EPA SWMM 5.1. Solusi ditarik dari hasil pengukuran elevasi dan pemodelan yang telah dilakukan. Berdasarkan pengukuran elevasi yang dilakukan, bagian timur perumahan memiliki elevasi yang lebih tinggi. Hasil pemodelan menunjukkan bahwa bagian yang rentan terjadi genangan ada di bagian selatan.
Kata Kunci — perumahan, elevasi, tata guna lahan, genangan
Tatort Syntax
Authors: Thormann Isabelle
Published: July 2024

Dieses Buch versteht sich einerseits als Lehrbuch für die forensische Linguistik. Zugleich ist es ein praxisorientierter Leitfaden zur Identifizierung anonymer Textverfasser:innen über ihre Sprachmuster. Anhand vieler Beispiele wird veranschaulicht, welch vielschichtige Informationen Texte und Sätze über ihre Verfasser:innen preisgeben. Im Vordergrund stehen qualitative Verfahren, in deren Rahmen auch eine sinnvolle Kodierung vorgestellt wird, die sich in der langjährigen Praxis der Autorin als öffentlich bestellte und vereidigte Gutachterin bewährt hat. Dieser verständliche und unverzichtbare Leitfaden enthält ein umfangreiches Glossar der Fachbegriffe, befasst sich auch mit der aktuellen Frage nach KI-generierten Texten und wendet sich nicht nur an Linguist:innen, sondern auch an Leser:innen aus den Rechtswissenschaften (insbesondere Richter:innen), der Informatik, Psychologie, Kriminologie und Kriminalistik.
Movement Analysis Of Bedincak Gymnastics Based On Traditional Dance Of Bangka Belitung
Authors: Srilestari Widia , Narawati Tati , Sukmayadi Yudi
Published: July 2024

The problem of this research is how Senam Bedincak can be an alternative recreational sport for the people of Bangka Belitung. The purpose of this study is to describe and analyze the choreographic and musical structure of Bedincak Gymnastics in Bedindak Gymnastics so that it becomes an alternative recreational sport for the people of Bangka Belitung. The method used is descriptive analysis with a qualitative approach. Bedincak Gymnastics is a community sport that adopts traditional Bangka Belitung dance movements such as Kedidi Dance, Dincak Dambus Dance and Measles Dance. The purpose of Bedincak Gymnastics is to improve the overall health and fitness of the community as well as to introduce and preserve Bangka Belitung culture to the community. Bedincak Gymnastics consists of 7 movement structures, namely opening movement, pattern 1 movement, pattern string movement, bedincak basic movement, pattern 2 movement, pattern 3 movement and closing movement.
Bubuka Lawang Dance in Nyiar Lumar as a Media for Cultural Communication in Ciamis
Authors: Intandiani Annastasya Nur , Musunah Juju , Narawati Tati
Published: July 2024

Dance performance is not merely a sequence of artistically arranged movements. Instead, a dance performance serves as a cultural communication medium between the creator and the audience. In the presentation of dance, expressed through each movement, there is meaning that goes beyond the physical aspects alone. Whether through harmonious movement or the selection of specific themes, a dance performance acts as a window that opens the audience's view into the world of emotions, values, and stories intended by the creator. The Bubuka Lawang Dance during Nyiar Lumar in Kawali, Ciamis Regency, West Java, showcases a community that continues to preserve and uphold its culture through Nyiar Lumar activities held every two years. Since 1998, Nyiar Lumar has been organized with the aim of building social solidarity through artistic activities in public spaces. This article aims to describe the research findings on the presentation of the Bubuka Lawang Dance during Nyiar Lumar in Kawali, Ciamis Regency. The research method employed is descriptive with a qualitative approach. The results reveal three stages in Nyiar Lumar: ngawalan (Opening ceremony), lalampahan (Journey), and magelaran (Performance). Additionally, there is a distinctive dance always featured during Nyiar Lumar titled "Tari Bubuka Lawang," with a different concept each year. Nyiar Lumar is closely related to the historical event of the Bubat War, which serves as the theme for Nyiar Lumar. The stage concept utilized is an outdoor stage with lighting relying on torches and candles. The movements are categorized into locomotion, pure movement, and symbolic gestures. Nyiar Lumar has become a biennial event to commemorate the history of West Java, Indonesia.
Technique as the “Last Love” of Humanity and the Anthropomodifying Factor in the Information Age
Authors: Solovieva Ludmila N. ,   Military Academy of Strategic Missile Forces named after Peter the Great – branch in Serpukhov,   Moscow Aviation Institute (National Research University)
Published: July 2024

This article engages in a socio-philosophical exploration of certain aspects of the interaction between man and technology at the present stage of development. It illustrates that the advent of the information age is accom-panied by profound socio-cultural changes closely intertwined and distinctly correlated with the key vectors of scientific and technological advancement, particularly emphasizing the pivotal role of information and commu-nication technologies. The article concludes on the deterministic and transformative influence of these technol-ogies on socio-cultural reality and on humanity itself, substantiating their anthropomodifying significance. It is noted that through the active incorporation of modern information and communication technologies into every-day life, humans endeavor to adapt to existence simultaneously within the realms of physical and digital worlds, navigating through vast volumes of information, virtual communication, and beyond. This adaptation process results in the alteration and expansion of the natural biopsychosocial nature of individuals. A logical outcome of such transformative technological influence is the emergence of a new type of human – technolog-ically advanced – endowed with qualities that determine their existence in the modern information-driven world.
Actual Problems of Modernity in the Cycle of Novels by A. Pérez-Reverte on the Spanish Civil War (1936–1939)
Authors: Tambiyants Yulian G. ,   Kuban State Agrarian University named after I.T. Trubilin, Shalin Viktor V. , Lukinov Andrey N. ,   Kuban State Agrarian University named after I.T. Trubilin,   Kuban State Agrarian University named after I.T. Trubilin
Published: July 2024

The article analyzes the works of the modern Spanish writer A. Pérez-Reverte on the theme of the Spanish Civil War, which, in combination with a number of scientific works, allow to reveal complex problems relevant to the modern world in general and to Russia in particular. The identified issues have structured the objectives of the study, namely: the political-practical, focused on defining conditions for optimal strategic success in wartime scenarios; the cultural-psychological, aimed at understanding human behavior during war through typologiza-tion; and the philosophical-ethical, seeking to delineate normative frameworks emergent amidst combat dy-namics. Based on the presentation and comprehension of the material, the authors have come to the following conclusions. Democratization, promoted by Western political correctness, increasingly shows itself as a de-structive factor in the growing need for social mobilization, hindering rather than facilitating the adoption of op-timal strategic decisions. In modern conditions, the social types of Zombart’s “bargainers” and “heroes”, as well as Gumilev’s passionaries, harmonious individuals and subpassionaries, which A. Pérez-Reverte’s works allow us to comprehend in greater depth, including with the intention of constructive use. Finally, Pérez-Reverte works propose an exploration of the phenomenon of humanistic heroism, whose values in a postmodernist context could serve as a resilient ideological foundation.
Political Risks of Russia’s National Security in the Confrontation with the West: Theoretical Analysis
Authors: Panesh Kaplan M. ,   Independent researcher
Published: July 2024

The study examines the political security risks of Russia in the confrontation with the West and the conduct of a special military operation in Ukraine. The author notes that the current risks in ensuring Russia’s security were predetermined by the political decisions taken by the country’s leadership after the collapse of the Soviet Un-ion. The analysis of the military-political situation in the country, which plays a priority role in ensuring the mili-tary security of the Russian Federation, is carried out. The causes of conflicts in the post-Soviet space, the role and place of state policy in ensuring military security are revealed. Based on the results of the analysis, prob-lems of organizational and legal regulation have been identified that require the elimination of negative factors. The ways of solving the problem of ensuring Russia’s military security at the present stage of development, taking into account new threats to military security, are determined. The author states that minimizing risks makes it possible to ensure strategic stability and national security of society, which is necessary to confront the collective West, as well as contributing to the construction, functioning and development of a military security system. Proposals are being made to improve the system of ensuring Russia’s military security and the need for a set of measures, including legal ones, as well as the use of existing potential.
The Concept of “Cultural Hegemony” by A. Gramsci in the Works of the Frankfurt School (M. Horkheimer, T. Adorno, and H. Marcuse)
Authors: Malyshko Yulia A. ,   Russian Presidential Academy of National Economy and Public Administration
Published: July 2024

The article analyzes the conceptual evolution of Antonio Gramsci’s notion of “cultural hegemony” as interpreted in Max Horkheimer and Theodor Adorno’s “Dialectic of Enlightenment” and Herbert Marcuse’s “One-Dimensional Man”. Spanning from Karl Marx’s publication of “Capital” in 1867 to Gramsci’s “Prison Notebooks” written in the 1920s and 1930s, over half a century elapsed. The socio-political panorama of their time, coupled with an analysis of the fragmentation of the workers’ movement alongside a communication revolution, ena-bled Gramsci to reformulate Marxist doctrine, introducing a new dimension: the level of mass consciousness and the competition among political forces for its control. These insights formed the basis of the works of the Frankfurt School authors. The aim of this study is to uncover the conceptual transformation of ideas concerning mass consciousness and its influence within the framework of neo-Marxist thought. Additionally, it examines critiques of the cultural industry and the power of brands within mass society.
The Perceptions of Accountancy Students on the Passing Rate of the Licensure Examination for Certified Public Accountants
Authors: Carator Maria Jean Montibon , Lavilla Joana Camelle , Pescadero Christian Paul , Pepania Artchelene D. , Sumicad Jr. Eligen H.
Published: July 2024

Purpose: This study aims to investigates the perceptions of 3rd-year accountancy students concerning the passing rates of the Licensure Examination for Certified Public Accountants (LECPA).Design/methodology/approach: This study utilized a qualitative research design with a multiple case study approach, the researchers employed in-depth interviews, observations, and data mining to explore students’ decisions to persist in pursuing CPA licensure or reconsider their career paths.Research Findings:  The results of the study indicated that some participants exhibited strong determination fueled by personal commitment, while others expressed hesitancy due to concerns about exam difficulty and the risk of failure. These insights emphasize the importance of robust support systems for aspiring Certified Public Accountants.Contribution/Originality/Novelty: The findings contribute valuable insights for academic institutions and educators to tailor effective support systems and interventions, advancing the understanding of career choices, educational motivation, and dynamics within the field of accountancy for 3rd-year students.
Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui persepsi mahasiswa akuntansi tahun ke-3 mengenai tingkat kelulusan Ujian Lisensi Akuntan Publik Bersertifikat (LECPA).Desain / metodologi / pendekatan: Penelitian ini memanfaatkan desain penelitian kualitatif dengan pendekatan studi kasus ganda, para peneliti menggunakan wawancara mendalam, observasi, dan penggalian data untuk mengeksplorasi keputusan siswa untuk tetap mengejar lisensi CPA atau mempertimbangkan kembali jalur karir mereka.Temuan Penelitian: Hasil penelitian menunjukkan bahwa beberapa peserta menunjukkan tekad yang kuat yang dipicu oleh komitmen pribadi, sementara yang lain menyatakan keraguan karena kekhawatiran akan kesulitan ujian dan risiko kegagalan. Wawasan ini menekankan pentingnya sistem pendukung yang kuat bagi calon Akuntan Publik Bersertifikat.Kontribusi / Orisinalitas / Kebaruan: Temuan ini memberikan kontribusi wawasan berharga bagi institusi akademis dan pendidik untuk menyesuaikan sistem pendukung dan intervensi yang efektif, memajukan pemahaman tentang pilihan karir, motivasi pendidikan, dan dinamika dalam bidang akuntansi untuk siswa tahun ke-3.
Homo offensus. Un ensayo sobre la disocialidad entre los seres humanos
Authors: Hernández Prado José
Published: July 2024

Procurando un acercamiento entre las ciencias sociohumanas y aquellas otras de la vida y la conducta, complementadas ambas por la filosofía, en partículas la del sentido común, este ensayo propone que el Homo offensus es un Homo sapiens que considera incuestionables, por evidentes de suyo, a las múltiples comunidades en las que se ha fragmentado a lo largo de la historia; que se reconoce como una sola y misma especie animal y que bien pudiera terminar extinguiendo al propio sapiens. El Homo offensus acompaño siempre la eusocialidad o sociabilidad cooperativa, altruista y armoniosa de las colectividades del Homo Sapiens con un disocialidad disruptiva, egoísta y conflictiva, tanto interna como externa, la cual entiende a la guerra como algo natural y normal, que se hay podido resolver con históricas formas legitimas de dominación política culminadas en la frágil democracia liberal moderna. Esta democracia quizás sea capaz de propiciar la paz perpetua entre las sociedades que conforman a la especie humana, por la que su inveterada disocialidad externa acaso puede convertirse en eusocialidad.
Digital transformation and agile methodologies: An innovative model for competitiveness in the manufacturing sector
Authors: Pacheco Alex , Mogrovejo Diana , Yupanqui Renato , Garay Joel , Uribe-Hernández Yrene
Published: July 2024

Currently, numerous companies intend to adopt digital transformation, seeking agility in their methodologies to reinvent products and services with higher quality, reduced costs and in shorter times. In the Peruvian context, the implementation of this transformation represents a significant challenge due to scarcity of resources, lack of experience and resistance to change. The objective of this research is to propose a digital transformation model that incorporates agile methodologies in order to improve production and competitiveness in manufacturing organizations. In methodological terms, the hypothetical deductive method was used, with a non-experimental cross-sectional design and a quantitative, descriptive and correlational approach. A questionnaire was applied to 110 managers in the manufacturing sector, obtaining a Cronbach’s alpha coefficient of 0.992. The results reveal that 65% of the participants consider that the level of innovation is regular, 88% think that the competition in their companies is of a regular level, and 76% perceive that the level of change is deficient. The findings highlight the importance of digital transformation in manufacturing companies, highlighting the adoption of agile methodologies as crucial to improving processes and productivity. In addition, innovation is essential to developing high-quality products and services, reducing costs and time. Digital transformation with agile methodologies redefines the value proposition, focusing on the customer and improving their digital experience, which differentiates companies in a competitive market.
Increased scientific research policies and the sustainable development of the education chain—Taking China as an example
Authors: Zhang Heng-Guo , Li Tailong
Published: July 2024

This paper models 54,559 Chinese news items about education industry and scientific industry by machine learning during the COVID-19 epidemic to build China’s increased scientific research policy (ISRP) index. The result of interrupted time series analysis indicates that, the ISRP has an emphatic positive causality on the education industry advancement and promotes the development of the education industry. The ISRP also has a remarkable positive causality on the development of the scientific industry. Moreover, the result of causal network indicates that, a virtuous circle within the ISRP, the education industry and the scientific industry has been formed, which has promoted the sustainable development of the education chain.
Palamede, inventore dei giochi da tavolo, corrispondenze planetarie e zodiacali nella Cronografia di Giovanni Malalas (5, 9) e nella filosofia del primo Ellenismo
Authors: Costanza Salvatore
Published: July 2024

Giovanni Malalas (490-570 ca.) offre nella Cronografia, un compendio di storia universale, un brano meritevole di essere analizzato con attenzione, perché enuclea la corrispondenza astrale tra i giochi da tavolo e i movimenti dei pianeti sul presupposto della simpatia cosmica. Queste analogie sono enunciate nel ritratto di Palamede, un eroe del ciclo troiano, reputato tradizionalmente il primus inventor di strumenti lusori quali dadi e pedine e delle corrispondenti tipologie ludiche. La fama dell’intelligenza di Palamede è ancora vitale nel periodo bizantino, come mostrano le menzioni antonomastiche di Anna Comnena, Eutimio Zigabeno, Giovanni Tzetzes. Il racconto di Malalas si rivela oltremodo interessante perché non si limita a ricordare il ruolo di geniale inventore dell’eroe, ma evidenzia altresì l’analogia tra i corpi celesti da un lato e il tavolo da gioco, le pedine e la torre usata per gettare i dadi dall’altro. Questa metafora astrologica non è una novità dello storico di origine siriache dell’età giustinianea, la filosofia post-aristotelica (Diodoro Crono, Clearco di Soli) ha, infatti, elaborato tale nozione, come conferma una citazione del libro di Svetonio Sui giochi dei Greci preservata dal dotto universale del XII secolo Eustazio di Tessalonica nei suoi commentari omerici. Una tradizione di lunga data è, quindi, attiva nella teoria della rispondenza astrale tra micro e macrocosmo nell’Antichità e nel Medioevo greco.
Research on Target Detection and Recognition Algorithms in Remote Sensing Images
Authors: Cai Wenlong
Published: July 2024

With the continuous improvement of computer vision and deep learning technology, the target detection methods of remote sensing images are also expanding and diversifying. In view of the shortcomings of the current object detection and recognition algorithms in terms of accuracy and versatility, this paper introduces the reverse scale transfer layer and feature pyramid (FPN) modules and applies the attention models of channel attention mechanism and spatial attention mechanism to each module of the convolutional neural network, so that the feature layer can obtain accurate and comprehensive prediction information, and finally proposes a remote sensing image object detection algorithm DCYOLOv7 with high accuracy. Compared with the benchmark model, the accuracy of the algorithm on small, medium, and large targets is improved by 14.69%, 4.14%, and 5.19%, respectively. The DC-YOLOv7 algorithm is improved by 10.15%, 12.16%, 13.18%, and 14.8% compared with the mAP, AP50, AP75, and AR100 of the benchmark algorithm, respectively. DC-YOLOv7 has a better detection application effect than the classical algorithm in the military aspect. The effectiveness and versatility of the target detection and recognition algorithm in the remote sensing images presented in this paper have been verified.
Research on the Interface Design of Smart Tourism APP for the Elderly Based on KANO-QFD
Authors: Zhou Lili
Published: July 2024

This paper analyzes the integration process of the Kano model and the QFD model, combines the advantages of the two, and proposes a method of obtaining the importance of user requirements based on the integration method of the QFD and Kano model. Organize older people’s smart tourism needs and use the Kano model analysis method to categorize each demand attribute. Obtain the self-scoring importance degree of the elderly demand, calculate the satisfaction index of the elderly demand, and get the comprehensive ranking of the importance degree centered on the elderly demand according to the SII, DDI, T
i, and K values of the demand elements. Clarify the elements of smart tourism APP interface design services, establish the relationship matrix between the needs of older people and the service index, and build the service quality house of smart tourism APP interface design for the elderly. Use the smart tourism APP functional interface planning strategy to present the functional design of the APP interface. It can be found that those with higher importance ratings are mainly basic functional requirements, attraction guides, and personalization center, of which the four importance indexes of U6 personalization center are U61=4.72, U62=4.75, U63=4.16, and U64=4.23. The calculation results of the quality house show that the importance of the service elements of the interface design of the APP for senior citizens’ smart tourism is ranked as APP content professionalism, service attitude, recommendation rationality, and service quality. Degree > service attitude > recommendation rationality > after-sale reliability.
Succinic semialdehyde dehydrogenase deficiency (SSADH-D) in an eleven-month-old infant with marked hypotonia and staring episodes: a case report
Authors: Mouskou Stella , Anagnostopoulou Katherine , Bikouli Danae , Paramera Efstathia , Papakonstantinou Evangelos , Korona Anastasia , Ziaka Vasiliki , Mavrikou Mirsini , Skouma Anastasia
Published: July 2024

Introduction

Succinic semialdehyde dehydrogenase deficiency (SSADH), also known as 4-hydroxybutyric aciduria (OMIM #271980, 610045), is an ultra-rare neurometabolic disorder inherited in an autosomal recessive pattern. It is usually characterised by a relatively nonprogressive encephalopathy in the first two years of life with hypotonia and developmental delay, associated with mild ataxia and hyporeflexia, as well as delays in language and speech development.

Case report

We report on a case of a four-year-old girl with SSADH deficiency who presented, at the age of 11 months old, with marked hypotonia, global neurodevelopmental delay and epilepsy. The diagnosis of “Succinic semialdehyde dehydrogenase deficiency” was indicated as there was a marked elevation of the levels of 4-hydroxy-butyric and 3,4-dihydroxybutyric acid caused by mutation at the gene ALDH5A1 in the homozygous state, identified with WES technique. Currently, she is four years old and has a severe global psychomotor delay, excessive hypotonia, hyperextensibility, and ataxia and is free of seizures.

Conclusion

At the early stage of clinical presentation, the condition is difficult to differentiate from other encephalopathies. This case report suggests that analysis of urinary organic acids should be performed in all patients at risk to allow early diagnosis. DNA analysis with the WES technique can confirm the diagnosis.
The use of ibuprofen as an anti-seizure medication: a systematic review
Authors: Tristan Ariel , Wijayahadi Noor , Kristina Tri Nur , Jaeri Santoso
Published: July 2024

Background

Epileptic seizure is a transient period of signs and symptoms resulting from the abnormal excessive and synchronous neuronal activity in the brain, resulting in brain damage. To prevent complications, the antiseizure medication is needed. Several agents have a potency of anti-seizure effect, including ibuprofen. Unfortunately, there are few studies regarding the anti-seizure effect of ibuprofen.

Aim

To determine the anti-seizure effect of ibuprofen to reduce the symptoms of epileptic seizures.

Materials and Methods

A systematic review using the databases ScienceDirect, SpringerLink, Nature, and Pubmed. The article was obtained using the keywords “ibuprofen” and (“epilepsy” or “anticonvulsant” or “antiseizure” or “epileptic” or “neuroinflammation”) in the period 2012 to 2022 and screened with inclusion and exclusion criteria. Out of the 1376 articles screened, there are three studies included in this review. The SYRCLE Risk of Bias Tool was used to assess the risk of bias, and the data was synthesised using SWiM guidelines.

Results

Ibuprofen affects seizures by reducing the number, grade, and duration of seizure intensity in the PTZ-induced rats. Despite the risk of bias assessment revealing some potential bias in the studies, our study shows that ibuprofen has potency as an additional agent for epileptic seizures among febrile convulsive patients.

Conclusion

In animal models of seizures, ibuprofen has an antiseizure effect by reducing the number, grade, and duration of seizures.
The Dog Bites: On the “Aggressive” Antipassive in Slavic and Baltic
Authors: Bondarenko Alice
Published: July 2024

Several Slavic and Baltic languages have an “aggressive” antipassive construction, where in a reflexive marker is used to mark object omission. The construction often carries habitual or potential aspectual meanings and is restricted to a small group of verbs. This study examines the lexical restrictions of the constructions across a sample of 11 Slavic and Baltic languages, with a special focus on Russian. The results show that across the languages, the construction is used to express a set of concepts, of which ‘hit’ and ‘push’ are the most prototypical. Verbs used in the antipassive express unwanted action on an animate patient, and they also share features of inherent atelicity and potential reciprocality. All languages in the survey display syncretism of reciprocal and antipassive markers, resulting in ambiguous plural subject constructions. Based on this, it is suggested that the “aggressive” antipassive with animate subjects has grammaticalized from the reciprocal function of the reflexive marker. Lexical semantics hence play an important role in the extension of functions of reflexive markers in these languages.
Las dos constituciones romanas: de la constitución antigua a la surgida en torno al poder imperial
Authors: Soza Ried María de los Ángeles
Published: July 2024

Estas reflexiones nacieron en el contexto del debate sobre el cambio constitucional que vivimos recientemente en el país. La contingencia nacional nos hizo pensar acerca del posible aporte de la experiencia romana al tema en cuestión. Al abordar el tópico, nos dimos cuenta de que era imposible avanzar sin discernir algunos temas previos que permitían situar bien el argumento de fondo: en primer lugar, era necesario resolver la cuestión relativa a la existencia o no de un sistema normativo, o de un ordenamiento jurídico en el derecho romano; la segunda, se refería al tema de lo público y lo privado, en el sentido de si el derecho romano reconoció la existencia de dos ámbitos de derecho, cada uno con sus propios principios y reglas. Una vez dilucidados ambos temas, pudimos avanzar en la propuesta que constituye el núcleo de este artículo, que es determinar si existió una constitución romana, y en qué términos ella pudo concebirse. En la segunda parte del escrito, pues, ofrecemos la idea de que, si bien ella efectivamente existió, quedó superada por un hecho de carácter político de la mayor importancia: el advenimiento del Principado. Con el devenir de los años y la concentración del poder en manos del emperador, esa primera constitución romana adquirió unas bases y principios distintos: es la razón que nos hace hablar de un verdadero cambio constitucional: de una segunda constitución romana.
Análisis de las sentencias de la Corte Suprema sobre indemnización de perjuicios derivadas de licitaciones públicas
Authors: Herrera Vargas Cristóbal
Published: July 2024

En los últimos años los Tribunales Superiores de Justicia han acogido demandas de indemnización de perjuicios deducidas por oferentes perjudicados en procesos de licitación pública. Esto importa un cambio relevante en la jurisprudencia previa de nuestros tribunales, puesto que eran renuentes al resarcimiento de los perjuicios, al sostener que la participación en un proceso licitatorio únicamente importaba una mera expectativa. Un factor relevante en este cambio lo constituyen las declaraciones de ilegalidad y arbitrariedad junto con la medida para restablecer el imperio del Derecho dictada por el Tribunal de Contratación Pública junto con la aceptación de la noción de pérdida de chance. Por lo que, procederemos a analizar la creación y funcionamiento de esta Magistratura especializada y qué entiende por acto ilegal y arbitrario. Luego, nos referiremos el concepto de mera expectativa, cuál es la noción de Responsabilidad del Estado utilizada por la Corte Suprema, para finalizar identificando cuáles son los criterios utilizados para acoger estas acciones y qué es lo que se indemniza mediante el análisis de sentencias.
Probabilistic Feature Matching for Fast Scalable Visual Prompting
Authors: Frick Thomas , Skura Cezary , Janicki Filip M. , Assaf Roy , Avogaro Niccolo , Caraballo Daniel , Cinar Yagmur G. , Ebouky Brown , Giurgiu Ioana , Katsuki Takayuki , Kluska Piotr , Malossi Cristiano , Qiu Haoxiang , Sakai Tomoya , Scheidegger Florian , Simeski Andrej , Yang Daniel , Bartezzaghi Andrea , Rigotti Mattia
Published: July 2024

In this work, we propose a novel framework for image segmentation guided by visual prompting which leverages the power of vision foundation models.

Inspired by recent advancements in computer vision, our approach integrates multiple large-scale pretrained models to address the challenges of segmentation tasks with limited and sparsely annotated data interactively provided by a user.

Our method combines a frozen feature extraction backbone with a scalable and efficient probabilistic feature correspondence (soft matching) procedure derived from Optimal Transport to couple pixels between reference and target images.

Moreover, a pretrained segmentation model is harnessed to translate user scribbles into reference masks and matched target pixels into output target segmentation masks.

This results in a framework that we name Softmatcher, a versatile and fast training-free architecture for image segmentation by visual prompting.

We demonstrate the efficiency and scalability of Softmatcher for real-time interactive image segmentation by visual prompting and showcase it in diverse visual domains including technical visual inspection use cases.
Enhancing Manufacturing with AI-powered Process Design
Authors: Genalti Gianmarco , Corbo Gabriele , Bianchi Tommaso , Missaglia Marco , Negri Luca , Sala Andrea , Magri Luca , Boracchi Giacomo , Miragliotta Giovanni , Gatti Nicola
Published: July 2024

Manufacturing companies are experiencing a transformative journey, moving from labor-intensive processes to integrating cutting-edge technologies such as digitalization and AI. In this demo paper, we present a novel AI tool to enhance manufacturing processes. Remarkably, our work has been developed in collaboration with Agrati S.p.A., a worldwide leading company in the bolts manufacturing sector. In particular, we propose an AI-powered tool to address the problem of automatically generating the production cycle of a bolt. Currently, this decision-making task is performed by process engineers who spend several days to study, draw, and test multiple alternatives before finding the desired production cycle. We cast this task as a model-based planning problem, mapping bolt technical drawings and metal deformations to, potentially continuous, states and actions, respectively. Furthermore, we resort to computer vision tools and visual transformers to design efficient heuristics that make the search affordable in concrete applications. Agrati S.p.A.'s process engineers extensively validated our tool, and they are currently using it to support their work. To the best of our knowledge, ours is the first AI tool dealing with production cycle design in bolt manufacturing.
InViTe: Individual Virtual Transfer for Personalized 3D Face Generation System
Authors: Jang Mingyu , Lee Kyungjune , Lee Seongmin , Tong Hoseok , Chung Juwan , Ro Yusung , Lee Sanghoon
Published: July 2024

With the expansion of the virtual communication industry using VR/AR, it has attracted increasing attention to enable users to represent their personalities in a 3D avatar. As the face of 3D avatars plays a crucial role in conveying human personality, a system that generates and manipulates 3D faces is desired. However, establishing the system is challenging due to the need for human effort and specialized knowledge. To fill this void, we present the Individual Virtual Transfer (InViTe), which enables the creation and customization of a 3D face according to the user's preference. Our proposed system is featured for 1) 3D face reconstruction with high fidelity texture map, 2) 3D face personalization, 3) realistic rendering results, and 4) real-time mobile virtual applications. We conduct an experiment to demonstrate that the proposed system can achieve sufficient individual personalization of 3D faces. Furthermore, we evaluate the system's data transmission protocol and demonstrate its efficiency. The demonstration video is available at https://www.youtube.com/watch?v=D 4pXZvGUWU.
Demo: Enhancing Wildlife Acoustic Data Annotation Efficiency through Transfer and Active Learning
Authors: Kath Hannes , P. Serafini Patricia , B. Campos Ivan , S. Gouvêa Thiago , Sonntag Daniel
Published: July 2024

Passive Acoustic Monitoring (PAM) has become a key technology in wildlife monitoring, generating large amounts of acoustic data. However, the effective application of machine learning methods for sound event detection in PAM datasets is highly dependent on the accessibility of annotated data, a process that can be labour intensive. As a team of domain experts and machine learning researchers, in this paper we present a no-code annotation tool designed for PAM datasets that incorporates transfer learning and active learning strategies to address the data annotation challenge inherent in PAM. Transfer learning is applied to use pre-trained models to compute meaningful embeddings from the PAM audio files. Active learning iteratively identifies the most informative samples and then presents them to the user for annotation. This iterative approach improves the performance of the model compared to random sample selection. In a preliminary evaluation of the tool, a domain expert annotated part of a real PAM data set. Compared to conventional tools, the workflow of the proposed tool showed a speed improvement of 2-4 times. Further enhancements, such as the incorporation of sound examples, have the potential to further improve efficiency.
ProMoAI: Process Modeling with Generative AI
Authors: Kourani Humam , Berti Alessandro , Schuster Daniel , van der Aalst Wil M.P.
Published: July 2024

ProMoAI is a novel tool that leverages Large Language Models (LLMs) to automatically generate process models from textual descriptions, incorporating advanced prompt engineering, error handling, and code generation techniques. Beyond automating the generation of complex process models, ProMoAI also supports process model optimization. Users can interact with the tool by providing feedback on the generated model, which is then used for refining the process model. ProMoAI utilizes the capabilities LLMs to offer a novel, AI-driven approach to process modeling, significantly reducing the barrier to entry for users without deep technical knowledge in process modeling.
LangXAI: Integrating Large Vision Models for Generating Textual Explanations to Enhance Explainability in Visual Perception Tasks
Authors: Nguyen Hung , Clement Tobias , Nguyen Loc , Kemmerzell Nils , Truong Binh , Nguyen Khang , Abdelaal Mohamed , Cao Hung
Published: July 2024

LangXAI is a framework that integrates Explainable Artificial Intelligence (XAI) with advanced vision models to generate textual explanations for visual recognition tasks. Despite XAI advancements, an understanding gap persists for end-users with limited domain knowledge in artificial intelligence and computer vision. LangXAI addresses this by furnishing text-based explanations for classification, object detection, and semantic segmentation model outputs to end-users. Preliminary results demonstrate LangXAI's enhanced plausibility, with high BERTScore across tasks, fostering a more transparent and reliable AI framework on vision tasks for end-users. The code and demo of this work can be found at https://analytics-everywhere-lab.github.io/langxai.io/.