bluuebunny/crossref_metadata_2025 huggingface dataset:
6. Investigating the Societal Impacts of Direct-to-Consumer Genetic Testing, and its Relationship to Mortality Salience, Attraction to Legacy and Attraction to Leisure
Authors: Crimi Laura
Published: April 2021

Homo sapiens are the only species that are aware that one’s life is impermanent, and that responds to that awareness with anxiety. Adaptive anxiety buffers include delusion through ‘legacy drive’ and ‘leisure drive’, which have been proposed as fundamental components in defining the evolutionary roots of human nature and sociocultural evolution. This study evaluates how legacy and leisure drive are impacted by mortality salience and ideas of genetic testing, and analyzes advancements in genomic technology and its societal implications. In this project, indicators of variation in legacy drive and leisure drive, due to mortality salience and genetic testing priming, were assessed based on participant responses (n=1449) from faculty and students at Queen’s University in an online survey. Direct-to-consumer personal genome testing is poised to usher in a new era of medicine through empowering individuals to learn and understand their own genetic make-up. Behavioural changes between sexes were evaluated in terms of Darwinian theory. This was assessed in conjunction with domains of legacy and connected with participant responses to recent and expanding opportunities for genomic testing—including in the context of so-called ‘designer babies—with potential for playing a role in modulating the evolution of humans both biologically and culturally. Results will be used to test for relationships between variation in demographic/gender traits and preferences associated with mortality awareness, and domains of legacy and leisure. Preliminary investigation reveals that mortality salience is positively correlated with both leisure and legacy drive. Further analysis of results will be presented at the conference.
9. Multiple Perspectives: An Orientation Resource for Queen’s Project on International Development Interns Working in Arviat (ᐊᕐᕕᐊᑦ), Nunavut with the Summer Camp Program
Authors: Jourdain Tessa
Published: April 2021

In 2011-2012 I was the Site Director for Queen’s Project on International Development’s (QPID) summer development project in Arviat, Nunavut. The project involves QPID Interns and the Site Director assisting the Arviat community in the coordination of their summer camp program. During my time in Arviat, I collected data from a variety of sources to inform the creation of an orientation resource for future Queen’s students working with the summer camp program. I used a blog to document my observations, interactions with the community, daily activities at camp, and the progression of my adjustment and adaptation to my experiences both in the job and in the community. Interns Katie Joyce and Holly Smith contributed information about their thoughts and observations of the community and the camp program. Also, Shirley Tagalik and Wendy Savikataaq, both community members, contributed information on Arviat’s history and culture. Three objectives of this resource include: 1) to develop an encompassing orientation resource for QPID Interns consisting of guiding information on all aspects of the project using a variety of perspectives; 2) to provide consistency and sustainability for QPID’s involvement through creating knowledge documentation of the project; and 3) to develop and encourage cross cultural knowledge sharing between Arviat and Kingston. As a tool for knowledge sharing that provides guidance and encourages a growing understanding of the Arviat community, this resource will be given to QPID electronically so that it can be built upon and refined over time.
13. Mitigating Avian and Bat Mortality at Wolfe Island’s Wind Facility
Authors: McDermott Tearney , Ehmann Victoria , McCord Chelsey , Morandi Garrett
Published: April 2021

This research focuses on exploring existing mitigation and modification options in order to develop appropriate recommendations to aid TransAlta Corporation in curbing bird and bat mortalities on Wolfe Island. Since the construction and operation of the Wolfe Island wind facility in Frontenac County, Ontario began in 2008, it has contributed to the deaths of many local and migratory birds and bats. While official tallies of avian and bat mortalities to date vary across reports, environmentalist groups and residents alike have expressed concerns for the safety of these species citing the facility’s position on a migratory route along the eastern end of Lake Ontario as a key point of contention (Bazillauskas, A. & Yatchew, A., 2011; Blackwell, R., 2012; Dierschke, J et al., 2006). In response, the power company behind the project, TransAlta Corporation, has begun conducting its own investigation into the issue and producing bi-annual monitoring reports of mortalities but has made no significant alterations to their turbines (TransAlta Corporation, 2012). As part of an effort to reduce the direct and indirect effects of the Wolfe Island wind facility on migrating bird and bat species, this report aims to assess the suitability for TransAlta corporation of certain mitigation options such as running turbines on a rotating schedule to account for the high traffic periods throughout the year when species are likely to be most at risk and avoiding the continuous lighting which attracts nocturnal species to the towers.
17. The State of Belle Park
Authors: Peters Garnet , Oliver Nadene , Oswald Sean , Rosenblat Howard
Published: April 2021

Our group used the Belle Park Golf course, located at 713 Montreal Street, as our project site. The course is located on top of a pre-existing dump that served as the city’s waste disposal site between the early 1950’s until 1974, it still shows signs of leachate seepage. The wildlife issue we explored is the effect of this leachate on the surrounding ecosystem, including tree species, fish and mammals. We researched case studies in similar situations that have been done in the past as a base for our understanding. The community entity are working with is the Environment Division of the City of Kingston, in charge of monitoring the hybrid poplar trees planted along the fairways. They are used as a means to extract contaminants from the soil, based on their proven ability for rapid growth. We will evaluate the effectiveness of this technique along with the vertical leachate extraction wells on site.  Also, our group hopes to obtain the history of the water sample data that is collected from monitoring wells around the site for our analyses and interpretation. The latest budget information shows that the golf course lost $203,000 last year. This has prompted city council to reconsider the future of the property and open the doors for new innovative ideas. As part of our project we hope to come up with a sustainable solution that preserves the natural habitat and serves the community, such as a park.
21. Invasion of Asian Carp in the Great Lakes
Authors: Smrekar Kassandra , Tanaka Shingo , Williams Lavie
Published: April 2021

A recent threat posed to the Great Lakes and adjoining waterways is the Asian Carp.  This large bodied fish originated from Asia and was first imported to the North American between 1960 to 1970. Their migration northward through the Mississippi River eliminated native freshwater species through competition of habitat and food resources. It is imperative to focus on the potential invasion of the Asian Carp because the risk assessment is high that the carp would eliminate all native species.  Currently the carp are at the border of entering Lake Michigan, which would then provide access to the rest of the freshwater regions in the surrounding area. Ultimately, the loss of lake biodiversity is the fundamental problem and is coupled with economic issues.  Bowfin Environmental Consulting INC and various invasive species awareness programs have been utilized to provide guidance on undertaking a project that involves an aggressive invasive species.  The challenge faced will be to determine a method in which to prevent the invasion of Asian Carp.  Examining their migration patterns, importation laws of live fish, and the policies of invasive species, will provide insight on the approach that should be taken to eliminate the threat of Asian Carp.  It is also important to analyze which native species are most susceptible to becoming extinct.  Overall, the intention is not only to increase government, scientific, and public awareness of this issue, but also to provide methods that can be implemented to prevent and eradicate the spread of Asian Carp in North American waterways.
23. Constitutively Active Signal Transducer and Activator of Transcription-3; an Oncogene that Increases Gap Junctional, Intercellular Communication
Authors: Trotman-Grant Aaron
Published: April 2021

Gap junctions are specialized intercellular channels that connect the cytoplasm of adjacent cells and mediate the direct exchange of small ions and molecules between them. Gap junctional intercellular communication (GJIC) is usually blocked, or down regulated, in cells transformed by oncogenes, such as Src. One of the Src effector pathways leading to transformation and GJIC suppression is the Ras/Raf/MEK/ERK pathway that has a prominent etiological role in cell proliferation, differentiation and cell survival; inhibition of this pathway in vSrc transformed cells restores GJIC. In addition, the distinct downstream effector of Src that is obligatory for neoplasia is the signal transducer and activator of transcription-3 (Stat3). Stat3 is up regulated in a range of tumors, and a modified version, the constitutively active form of Stat3 (Stat3C), has been shown to function as an oncogene. To examine the role of Stat3 upon the Src-mediated, GJIC suppression, Stat3 was down regulated in rat liver epithelial T51B cells expressing activated Src. The extent of GJIC was determined by the migration of the fluorescent dye, Lucifer Yellow, through adherent cells subsequent to electroporation. The results demonstrate that, contrary to inhibition of the Ras pathway, Stat3 inhibition in cells expressing activated Src does not restore GJIC. On the contrary, Stat3 inhibition in normal cells with high GJIC levels eliminated junctional permeability. Interestingly, our results also demonstrate that expression of Stat3C T51B cells and human lung cancer SK-LuCi6 cells, which have extensive communication and low Src levels, increased GJIC. Therefore, Stat3 is actually required for and increases junctional permeability.
Novel Integration of Administrative Pharmacy Residents in a Management Course
Authors: Ford James , Rotzenberg Katherine , Mott David
Published: April 2021

Background: Management skills are an essential component of a pharmacy graduate’s abilities for successful practice.  Although pharmacy education standards require that students have a working knowledge of management principles, students often do not see the value in management and business courses.  One innovative approach is restructuring course content using case examples and real-world experiences to improve student understanding of finance and management principles.
Innovation: Two specific changes were implemented in a second year (P2) management and finance course to improve the relevance of business principles.  Course content was organized around current pharmacy service cases from a variety of practice settings and supported by the value of problem-based learning.  Post-graduate year 1 (PGY-1) administrative pharmacy residents were engaged as course teaching assistants (TAs) who brought real-world experiences into the class.  An analysis of pre- and post-course voluntary surveys, course evaluations, and TA evaluations assessed the impact of the course redesign.
Findings: The course redesign achieved its intended goal of improving student-perceived course relevance.  This was shown through statistically significant improvements in course evaluations that were intended to measure student perception of pharmacy management and its relevance in their future career.  Student completed TA evaluations showed that those who reported their TA shared real-world applications had higher confidence in applying course concepts and greater understanding of course materials.
Conclusions: Administrative pharmacy residents were successfully integrated into a pharmacy management course redesign, resulting in improved student perceptions of course relevance.
EFICÁCIA DA REVASCULARIZAÇÃO NA FORMAÇÃO DO ÁPICE RADICULAR EM PACIENTES COM RIZOGÊNESE INCOMPLETA: UMA REVISÃO INTEGRATIVA
Authors: REIA Verônica Caroline Brito , MOLITOR Pedro , PIRAS Fernanda Furtado , CAMARGO Marcelo Ueti de , MAGRO Miriam Graziele
Published: April 2021

Objetivos: Verificar a eficácia da revascularização para induzir a continuidade de formação do ápice radicular em pacientes com rizogênese incompleta. Metodologia: A estratégia de busca foi aplicada nas bases de dados eletrônicas PubMed, Embase, Web of Science e LILACS, sendo selecionados quatro artigos publicados entre 2011 e 2021. Resultados: Um total de 27 pacientes diagnosticados com necrose pulpar foi incluído, de ambos os sexos. Os testes de percussão, térmico e elétrico no exame clínico foram realizados em 4 pacientes. Todos os pacientes fizeram radiografia periapical para análise inicial. O tratamento endodôntico foi realizado com indução do sangramento apical do canal radicular para revascularização em todos os estudos. No acompanhamento de até 4 anos, observou-se, radiograficamente, aumento do comprimento e espessura radicular, diminuição e posterior desaparecimento da radioluscência periapical, estreitamento do ápice radicular, desenvolvimento radicular e redução da lesão periapical. Conclusão: A revascularização permite que, mesmo após o estímulo para indução de sangramento, a região periapical continue a formação radicular por mais tempo quando comparada a outros materiais endodônticos.

 

THE EFFECTIVENESS OF REVASCULARIZATION ON ROOT APEX FORMATION IN PATIENTS WITH IMMATURE PERMANENT TEETH: AN INTEGRATIVE REVIEW

 

ABSTRACT

Objectives: To verify the effectiveness of revascularization to induce further root apex formation in patients with immature permanent teeth. Method: A searching strategy was performed at PubMed, Embase, Web of Science, and LILACS electronic database, four articles issued between 2011 and 2021 were screened. Results:  A total of 27 patients diagnosed with pulp necrosis were included, both genders. Percussion, electric, and thermal pulp testing were performed for clinical examination in those 4 patients. All the patients had a periapical x-ray taken for initial analysis. The endodontic treatment was performed with the apex-induced bleeding into the root canal for the revascularization in all the studies. At a 4-year follow-up it was observed, radiographically, an increase in root length and thickness, and afterward the periapical radiolucency disappearance, the root apex narrowing, root growing, and the periapical lesion reduction. Conclusion: Revascularization enables, even after the stimulus for bleeding induction, the periapical region to further continue the root formation when compared to other endodontic materials.  

 

Descriptors: Endodontics. Pulp Necrosis. Tooth Apex.
Intervención psicológica en personas con enfermedad renal crónica en hemodiálisis
Authors: Becerril González Mariana
Published: April 2021

Introducción: La enfermedad renal crónica es un padecimiento que deteriora el funcionamiento de los riñones de manera constante, progresiva e irreversible; por ello, es necesario fomentar la adherencia al tratamiento a favor de la calidad de vida y mejorar así los mecanismos de adaptación de quienes lo sufren. Objetivo: Incrementar la adherencia al tratamiento y los mecanismos de adaptación psicológicos, afectivos y sociales en adultos con enfermedad renal crónica en etapa 4-5 dentro del programa de hemodiálisis de un hospital de alta especialidad del Estado de México. Método: Se evaluó a un total de 16 personas con la Escala de Adherencia Terapéutica, y los mecanismos de adaptación de las personas con ERC en terapia de hemodiálisis, aplicándoseles un programa de once sesiones grupales por semana, con enfoque cognitivo-conductual y terapia racional emotiva. Resultados: Las puntuaciones de preevaluación y postevaluación mostraron que los mecanismos de adaptación aumentaron significativamente, y asimismo el puntaje de adherencia al tratamiento, manteniéndose el control de ingesta de medicamentos y alimentos. Discusión: El programa es útil en la muestra para incrementar los mecanismos de adaptación y adherencia al tratamiento.
Conflicto relacional y el estrés en el bienestar subjetivo y la satisfacción de parejas con cardiopatía
Authors: Bravo-Doddoli Andrea , Sánchez-Aragón Rozzana
Published: April 2021

La enfermedad cardiaca no solo tiene efectos en el paciente sino también en su pareja, debido a que al generar estrés puede facilitar la experiencia de conflicto en la relación, ya sea por motivos como las demandas de la enfermedad, la capacidad de enfrentarla, así como cuestiones más extremas como los sentimientos de pérdida o incluso el temor de la muerte de la pareja y el abandono que implicaría. Cuando el conflicto es frecuente en las relaciones de pareja genera emociones negativas, causando un malestar que impactará directamente en la evaluación que se hace de la relación. Por lo anterior, esta investigación tuvo como objetivos: 1) examinar las diferencias en los motivos de conflicto, estrés, bienestar subjetivo y satisfacción con la relación en hombres y mujeres con cardiopatía y sus parejas sanas; y 2) identificar los efectos de los motivos de conflicto y el estrés en el bienestar subjetivo y satisfacción con la relación. Para ello participaron 204 parejas heterosexuales, en las cuales uno de los miembros tiene una cardiopatía y el otro estaba sano al momento de la aplicación. Los hallazgos demostraron diferencias estadísticamente significativas entre sexos que indican que ellas experimentan más conflictos por indiferencia, actividades de la pareja y adicciones; y tienen más descontrol ante el estrés y emociones negativas en comparación con los hombres. Asimismo, se observaron diferencias en los conflictos por religión en donde se observa que son las mujeres sanas quienes los reportan más. Finalmente, se observaron –en general– efectos negativos del conflicto y el estrés en el bienestar subjetivo y en la satisfacción con la relación.
Isolasi dan karakterisasi bakteri yang berpotensi mengikat aflatoksin di rumen sapi
Authors: Sisriyenni Dwi , Suryahadi Suryahadi , G Wiryawan Komang , Evvyernie Dwierra , Pantaya Dadik
Published: April 2021

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh aflatoksin terhadap fermentasi rumen secara in vitro dan untuk mendapatkan isolat bakteri rumen yang mampu mengikat aflatoksin. Percobaan terdiri dari tiga tahap, tahap pertama adalah penurunan aflatoksin didalam rumen yang dilakukan secara in vitro. Tahap kedua adalah isolasi dan karakterisasi bakteri rumen yang bisa mengikat aflatoksin, dan tahap ketiga adalah uji daya ikat aflatoksin oleh bakteri rumen. Penelitian ini menggunakan rumen sapi yang didapatkan dari rumah potong hewan (RPH) Bubulak Bogor. Rancangan penelitian menggunakan rancangan acak kelompok (RAK) faktorial 2x3 dan 2 ulangan. Faktor pertama adalah kandungan aflatoksin (tanpa dan penambahan aflatoksin), faktor kedua adalah jenis pakan (ransum dan glukosa), dan faktor ketiga adalah waktu inkubasi (0 dan 4 jam). Hasil penelitian menunjukkan kandungan aflatoksin tidak mempengaruhi kondisi rumen (pH, volattile fatty acid (VFA), dan konsentrasi asam laktat rumen), dari hasil isolasi didapatkan 6 isolat dan bakteri rumen yang dapat mengikat aflatoksin hingga 50%.
Hubungan Ekspresi Protein 16 (p16) dengan Derajat Histopatologik dan Invasi Perineural pada Karsinoma Sel Skuamosa Kepala dan Leher
Authors: Musyarifah Zulda , Agus Salmiah , Yenita Yenita , Hardisman Hardisman
Published: April 2021

Protein 16 (p16) merupakan salah satu protein supresor tumor yang memiliki peran dalam patogenesis Karsinoma Sel Skuamosa (KSS) kepala dan leher. Peran protein ini berbeda sesuai dengan faktor risiko paparan karsinogen dan memiliki implikasi terhadap faktor prognostik patologik. Tujuan: Menentukan hubungan protein 16 dengan derajat histopatologik dan Invasi Perineural (IPN) pada KSS kepala dan leher. Metode: Penelitian ini merupakan cross-sectional study dengan sampel sebanyak 60 kasus KSS kepala dan leher yang telah didiagnosis di Laboratorium Patologi Anatomik RSUP Dr. M. Djamil Padang periode Januari 2016 sampai Desember 2018. Sampel diperoleh secara simple random sampling dari blok parafin yang berasal dari jaringan tumor. Dilakukan penilaian ulang pada slaid histopatologik untuk menilai derajat histopatologik dan invasi perineural. Ekspresi p16 pada sel tumor dilihat dengan pulasan imunohistokimia. Korelasi dilakukan analisis statistik bivariat menggunakan uji Chi-square dengan tingkat kemaknaan p<0,05. Hasil: Ekspresi p16 positif didapatkan pada 24 kasus (40%) dengan kasus terbanyak pada KSS kepala dan leher derajat tinggi, sedangkan pada 36 kasus (60%) tidak terdapat ekspresi p16. Ekspresi p16 positif memiliki hubungan yang bermakna dengan derajat histopatologik (p = 0,002) namun tidak terdapat hubungan antara ekspresi p16 dengan IPN (p = 1,000). Simpulan: Ekspresi p16 positif berhubungan dengan derajat histopatologik tumor yang lebih tinggi namun p16 tidak tidak berhubungan dengan kejadian invasi perineural pada KSS kepala dan leher.Kata kunci: derajat histopatologik, ekspresi p16, invasi perineural, KSS kepala dan leher
Gambaran Infeksi Nontuberculous Mycobacteria (NTM) pada Penderita Suspek TB Paru Menggunakan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) Kit
Authors: Akbar Putri Wulan , Iskandar Agustin , Astuti Tri Wahju , Indriana Kristin
Published: April 2021

Infeksi paru akibat Nontuberculous Mycobacteria (NTM) dan Mycobacterium tuberculosis (MTB) dapat memberikan gambaran klinis yang serupa sehingga berpotensi menyebabkan kesalahan diagnosis dan terapi. Pemeriksaan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) merupakan pemeriksaan berbasis molekuler untuk mendeteksi gen rpoB, IS1660 dan mtp40 yang dapat digunakan untuk membedakan infeksi NTM dari infeksi TB. Tujuan:  Mendapatkan gambaran infeksi NTM menggunakan MPCR-ULFA pada penderita terduga TB paru. Metode: Penelitian ini merupakan studi deskriptif dengan pendekatan potong lintang yang dilaksanakan sejak April sampai Juli 2019. Sebanyak 39 sampel sputum dari pasien terduga TB paru dari RSUD Kanjuruhan Kepanjen, Kabupaten Malang diperiksakan apusan BTA, GeneXpert dan MPCR-ULFA. Hasil: Sebanyak 5 sampel (12,8%) sputum dari pasien terduga TB paru terdeteksi sebagai NTM positif menggunakan pemeriksaan MPCR-ULFA. Empat dari lima sampel (80%) tersebut memiliki kesesuaian dengan hasil GeneXpert dan apusan BTA, yakni MTB negatif.  Pemeriksaan molekuler baik GeneXpert maupun MPCR-ULFA keduanya mendeteksi keberadaan gen rpoB dari Mycobacterium. Metode MPCR-ULFA mengamplifikasi 3 gen target sekaligus (IS1660, mtp40 dan rpoB) sehingga dapat mendeteksi infeksi NTM atau MTB. Simpulan: Prevalensi NTM pada pasien terduga TB paru di RSUD Kanjuruhan Kepanjen menggunakan MPCR-ULFA mencapai 12,8%. Sebanyak 80% dari NTM positif memiliki hasil pemeriksaan GeneXpert dan apusan BTA negatif.Kata kunci: GeneXpert, MPCR-ULFA, NTM, suspek TB paru
Efektifitas Metode William's Flexion dan Yoga Terhadap Intensitas Nyeri Punggung Bawah pada Ibu Hamil Trimester III di Kota Tanjungpinang Tahun 2019
Authors: Rahmadona Rahmadona , Batubara Kartika Sri Dewi
Published: April 2021

Nyeri punggung bawah pada kehamilan merupakan nyeri pada area lumbosacral. Hal ini sangat mengganggu aktivitas harian ibu hamil yang apabila tidak ditangani dapat menyebabkan kualitas hidup ibu hamil menjadi buruk. Beberapa terapi non farmakologis seperti latihan William’s flexion dan yoga dapat diupayakan mengatasi keluhan nyeri punggung bawah pada kehamilan.Tujuan: Menentukan efektifitas metode William’s flexion dan yoga terhadap intensitas nyeri punggung bawah pada ibu hamil trimester III di Kota Tanjungpinang tahun 2019. Metode: Penelitian ini adalah pra eksperimen dengan two group pre test post test design terhadap 60 sampel yang terbagi dua kelompok yaitu kelompok William’s flexion dan yoga. Data dikumpulkan dari Agustus hingga Oktober 2019, kemudian diukur menggunakan skala ukur numerik . Analisis data menggunakan t-test dependent  dan  independent. Hasil: Penelitian menunjukkan uji rerata dalam tiap kelompok perlakuan  menunjukkan hasil bermakna (p=0,000) dengan selisih rerata penurunan intensitas nyeri punggung bawah pada kelompok William’s flexion sebesar 1,27 dan kelompok yoga sebesar 2,50. Uji rerata antar kelompok perlakuan juga menunjukan hasil bermakna(p=0,000). Simpulan: Metode William’s flexion dan yoga efektif menurunkan intensitas nyeri punggung bawah.  Latihan yoga memberi penurunan intensitas nyeri lebih besar daripada latihan William’s flexion sehingga kedua metode ini bisa dipakai untuk mengatasi keluhan nyeri punggung bawah pada ibu hamil trimester III.Kata kunci: nyeri punggung bawah, William’s flexion, yoga
PERENCANAAN KEUANGAN DANA PENSIUN MELALUI METODE TIME VALUE OF MONEY DENGAN MENGGUNAKAN KALKULATOR FINANSIAL
Authors: Purnama Eka Desy , Frederica Diana , Adirinekso Gidion , Iskandar Deni , Subagyo Subagyo
Published: April 2021

Tujuan kegiatan ini adalah (1) untuk memberikan wawasan pentingnya perencanan keuangan sejak dini untuk persiapan masa pensiun kepada masyarakat, khususnya kepada jemaat GKI Bogor Baru. Fokusnya adalah beberapa alternatif investasi keuangan yang dapat dilakukan sesuai dengan profile risiko. (2) memberikan praktek perhitungan future value dana pensiun yang harus disediakan pada masa pensiun nanti, dengan memasukkan time value of money melalui aplikasi kalkulator finansial. Metode yang digunakan adalah penyuluhan dan pelatihan melalui presentasi materi oleh tim pengabdian kepada masyarakat, diskusi dengan peserta dan dipandu oleh moderator melalui aplikasi zoom. Umpan balik pelaksanaan kegiatan ini dilakukan dengan pengisian kuesioner melalui google form. Hasil kegiatan ini menunjukkan bahwa (1) melalui pelaksanaan kegiatan ini, peserta telah memahami perencanaan keuangan untuk masa pensiun dan memahani beberapa alternatif investasi keuangan sesuai dengan profile risiko masing-masing; (2) peserta mampu menghitung kebutuhan alokasi dana pensiun masa depan melalui penghitungan future value menggunakan aplikasi kalkulator finansial.
PENDAMPINGAN GIAT INOVASI DALAM DESIGN PROMOSI PRODUK DAN PENGELOLAAN KEUANGAN MELALUI PENGGUNAAN APLIKASI PLAYSTORE UNTUK MENINGKATKAN PENJUALAN DI MASA PANDEMI COVID-19 PADA KOMUNITAS LAPAK WARGA/UMKM PERMATA PAMULANG
Authors: Sugiyarti Listya , Hanah Siti , Asmilia Nur
Published: April 2021

Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah (1) untuk memberikan wawasan dalam mendesign promosi produk yang menarik (2) memberikan wawasan dalam membuat pembukuan yang baik dan tepat pada pengelolaan keuangan (3) untuk memperkenalkan aplikasi play store pada smartphone yang mendukung design promosi produk menjadi menarik (4) memperkenalkan aplikasi play store pada smartphone dalam mendukung pembukuan keuangan yang baik dan tepat sehingga pengelolaan keuangan menjadi akuntabel, (5) memberikan praktek dalam bentuk tutorial design promosi produk yang menarik dengan aplikasi play store dari smartphone (6) dan memberikan praktek dalam bentuk tutorial membuat pembukuan dengan menggunakan aplikasi play store dari smartphone. Metode yang digunakan adalah pendampingan dan pelatihan dengan pendekatan service learning melalui presentasi materi dan toturial oleh tim pengabdian kepada masyarakat secara tatap muka dengan prokes ketat di masa pandemi Covid-19. Unpam balik dari kegiatan ini dengan pengisian kuesioner dari para peserta. Hasil dari kegiatan pengabdian adalah untuk mendesign promosi produk dan pembukuan dengan aplikasi yang ada di play store smartphone. Peserta mampu mempraktekan aplikasi play store pada smartphone mereka dengan mendownload aplikasi yang direkomendasikan yaitu pixelLab untuk design promosi produk dan buku warung UMKM untuk membuat pembukuan dengan mudah. Aplikasi pixelLab dan buku warung UMKM ini sangat bermnafaat untuk para peserta dalam mendukung usaha mereka. Program kegiatan ini telah berhasil dilaksanakan dengan hasil yang memuaskan.
PELATIHAN KONSEP ANALISIS LAPORAN KEUANGAN KEPADA UMKM
Authors: Mayangsari Sekar , Banjarnahor Erliana , Lenggogeni Lenggogeni Jakarta , Nasution Kevin M. Pransilva
Published: April 2021

Abstrak:Tujuan dari pelaksanaan kegiatan Pengabdian kepada Masyarakat (PkM) ini membantu UMKM membuat laporan keuangan yang mengacu kepada Standar Akuntansi Keuangan Entitas tanpa Akuntanbilitas Publik (SAK-ETAP) serta memahami konsep analisis laporan keuangan. Kegiatan PkM ini yang merupakan kegiatan yang berkesinambungan. Dalam pelatihan, metode dilakukan dengan daring dengan menggunakan aplikasi zoom. Dalam pelatihan dilakukan diskusi dengan peserta yang dipandu oleh moderator melalui aplikasi zoom. Dilakukan pula umpan balik terhadap peserta dengan kuesioner melalui google form. Hasil evaluasi dari pelaksanaan PkM menunjukan bahwa peserta PkM menyatakan puas terhadap kegiatan, dan tujuan PkM tercapai dimana peserta memperoleh manfaat berupa pengetahuan, pemahaman dan ketrampilan tentang konsep analisis laporan keuangan UMKM. Abstract:The purpose of implementing this Pengabdian kepada Masyarakat (PkM) activity is to help MSMEs create financial reports that refer to the Financial Accounting Standards Entities without Public Accountability (SAK-ETAP) and understand the concept of financial statement analysis. This PkM activity is ongoing. During the training, discussions were held with participants guided by a moderator through the zoom application. Feedback was also carried out to participants with a questionnaire via a google form. The results of the evaluation of the implementation of PkM show that the PkM participants expressed satisfaction with the activities, and the PkM objectives were achieved where the participants benefited in the form of knowledge, understanding, and skills about the concept of analysis of SME financial statements.
Abdominal desmoid-type fibromatosis – a case report and an overview of treatment options
Authors: Koszarska-Mirek Justyna , Orleański Jakub
Published: April 2021

Fibromatosis (desmoid, desmoid tumour) is a tumour belonging to the group of fibrous tissue proliferative diseases. Although the tumour cannot produce distant metastases, it shows local malignancy by invading adjacent tissues, as well as high recurrence rates after local resection. The incidence of fibromatosis is 2-4 cases per 1 million inhabitants per year. Three types of fibromatosis have been distinguished: extra-abdominal, abdominal wall and intra-abdominal type. Although the most common types are sporadic, coexistence with familial adenomatous polyposis (FAP), known as the Gardner’s syndrome, is observed. Available therapeutic options include surgical treatment, watchful waiting, hormone therapy, non-steroid anti-inflammatory drugs, chemotherapy and radiation therapy. This case report aims to draw attention to the difficulties in selecting an appropriate treatment option, limited surgical treatment, the psychological aspect of the disease, as well as the need to actively search for modern diagnostic and therapeutic solutions. We present a case of a 26-year-old patient who was ultimately diagnosed with a desmoid tumour invading the abdominal wall and internal abdominal organs. The patient presented to a county hospital due to suspected gastrointestinal obstruction. It was found from medical history that the patient had palpated a tumour of the abdominal wall 9 months before admission.
Plastic and reconstructive surgeries of the anal canal
Authors: Kołodziejczak Małgorzata , Ciesielski Przemysław , Diuwe Piotr
Published: April 2021

Anal canal plasty is used to treat anal deformities, congenital defects and cosmetic disfigurements. The range of surgeries includes simple aesthetic procedures, as well as extensive sphincter reconstruction and anal strictureplasty. Plasty of hypertrophied anodermal folds is the most common cosmetic procedure. Anal deformations requiring surgical treatment include those causing anal canal deformation of functional importance. Perinatal injuries are the most common cause of this type of sphincter damage. Other include postoperative keyhole deformities and a ”gaping anus”. Another group of deformities includes anal stricture (postoperative, due to chronic inflammation in this region, post-traumatic or induced by radiation therapy) and lesions associated with the treatment of anal neoplasms. Surgical treatment of congenital anal defects is often initiated already in early childhood and performed by multidisciplinary teams led by paediatric surgeons. In the later period of treatment, these patients may require proctological interventions due to anal stricture or anal sphincter dysfunction as a result of surgeries. Plastic and reconstructive surgeries of the anal canal are mostly complex procedures requiring experience and should be performed in reference centres. Appropriate patient qualification and preparation for surgical treatment seem to be essential. Preoperative imaging and functional diagnosis is of key importance.
Profesor Edward Loth – Sprawiedliwy Wśród Narodów Świata za sprawą doktora Ludwika Stabholza
Authors: Ciesielska Maria
Published: April 2021

Professor Edward Loth was an outstanding scientist, author of numerous scientific dissertations, including 7 monographs cited all over the world to this day. The life and scientific achievements of prof. Loth have been described in many detailed studies focusing both on his didactic activities and active participation in the fight against the German invader during World War II. Due to the military experience gained during World War I and the Polish-Bolshevik war of 1920 as well as the medical specialization in the field of orthopedics and rehabilitation, prof. Loth was especially qualified to manage the sanitary facilities of the Home Army during the German occupation in Poland. Almost all studies show that Professor Loth was awarded, among others The Order of Virtuti Militari and that he was given the title of “Righteous Among the Nations”. Unfortunately none of the existing articles describe the circumstances in which Professor helped Jews and who applied for his candidacy for this prestigious distinction. Due to the scientific research on the history of the doctors of the Warsaw ghetto, the author reached documents and accounts describing the so-called ”rescue story” and the name of the person whom help was given.
Fournier gangrene – ward experience
Authors: Tański Zbigniew , Jarząbek Zbigniew , Konowalski Bartosz , Truszkowski Maciej , Biedrzycki Jakub , Kuzaka Bolesław , Kuzaka Piotr
Published: April 2021

Introduction. Fournier’s gangrene is a necrotising soft-tissue infection characterized by insidious and rapid onset. It belongs to the group of necrotising soft-tissue infections. The disease is more common in patients with systemic predispositions such as diabetes mellitus, obesity, hepatic cirrhosis, cancer, etc. Aim. The results of medical treatment thirtieths patients (man from 34 to 84 years old, middle age 67 years old) and co-morbidity with Fournier’s gangrene was presented. Material and methods. The co-morbidity was discussed and analized. The patients were treated by antishock therapy, proper antibiotic therapy was applied. The complications were presented during treatment, procedures with wounds, debridement and wounds treatment and final treatment skin deficiency. All patients had covered skin deficiency by mesh grafts, they were discharged from hospital with healed wounds or almost healed. Treatment from medical literature dealing with treatment and experience of Urological Wards was also presented (Fournier’s gangrene is a part of this disease). Results. Mortality was not observed in this group of patients. Conclusions. Fournier’s gangrene is a rapid-onset, life-threatening, acute urological disease requiring immediate diagnosis, as well as anti-shock and antibacterial therapy combined with intensive surgical debridement followed by the management of skin and soft tissue defects.
Surgical treatment of rapidly advancing active ulcerative colitis: a case report
Authors: Glinkowski Sławomir , Marcinkowska Daria
Published: April 2021

Ulcerative colitis is an inflammatory bowel disease with various clinical presentation. Due to an impaired immune response, diffuse inflammation develops in the intestinal tissue, which leads to bleeding and diarrhoea. The basis for diagnosis is the clinical presentation and the result of colonoscopy which confirms the presence of inflammatory lesions in the colon. The authors present the case of a patient admitted to their department following two previous hospitalisations at other centres who was suffering from active ulcerative colitis. After bacterial aetiology of the disease was excluded and conservative treatment was attempted at a gastroenterology ward, the patient was referred to a surgical department. During the previous hospitalisation colonoscopy was performed in which a lesion was observed in the splenic flexure, which precluded the visualisation of the further part of the colon. A colonoscopy performed at the surgical department did not confirm the presence of that lesion; however, it did reveal multiple pseudopolyps. Due to rapidly progressing cachexia and anaemia and a lack of improvement following attempted pharmacological treatment, a decision was made to perform an urgent colectomy with end ileostomy. After a week-long preparation of the patient (parenteral nutrition, packed red blood cells transfusion), pancolectomy was performed. Histopathological examination confirmed acute phase ulcerative colitis. In the postoperative period massive wound infection developed, which was treated for 14 days with vacuum therapy (VAC). The patient was treated for 30 days at the surgical department. He was discharged in a good general condition and instructed to report to his outpatient care centre.
Animal hair as a rare cause of pilonidal sinus – a case report
Authors: Dutkiewicz Paweł , Ciesielski Przemysław
Published: April 2021

Pilonidal sinus is a chronic inflammatory disease caused by the penetration of hair into the skin. Most often, it is located in the intergluteal area, but it may also develop at a different location. It is usually caused by the penetration of human hair, but animal hair can alaso cause it in rare cases. In the world publications, there are reports of the disease in other, often distant locations, e.g. the suprapubic area, armpit, foot, penis, umbilicus, eyelid, clitoris, intermammary cleft, nose, or scar after removing a Tenckhoff catheter. Usually, it is human hair that causes the formation of pilonidal sinus, but the literature also reports cases caused by animal hair in people who shear sheep. There is no other Polish publication describing pilonidal sinus of animal origin. The article presents a case of atypical pilonidal sinus caused by animal hair, located between the fingers of the patient who is professionally involved in shearing dogs. In the presented clinical case, treatment involved staged fistulotomy with the use of surgical thread. The patient was cured and full function of the hand was preserved. Staged fistulotomy is a safe procedure and can be used to treat pilonidal sinus of the hand.
The cradle of Western medicine
Authors: Lluch Alberto
Published: April 2021

The origins of Western Medicine can be found through the Greeks and the Romans, originally with Mythological figures represented by the god Asclepius, and later by Greek doctors such as Hippocrates and Galen. Roman medicine was highly influenced by the Greek medical tradition, relying more on naturalistic observations rather than on spiritual rituals. The writings of Galen survived more than other medical scriptures in antiquity. His theories dominated and influenced Western medical science for more than 1,300 years. This acceptance led to the spread of Greek medical theories throughout the Roman Empire, and thus a large portion of the West. Most of the actual medical terms are of Greek origin, as they were the founders of rational medicine in the golden age of Greek civilization. The Hippocrates were the first to describe diseases based on observation, and the names given by them to many conditions are still used today. On the other hand, most anatomical terms are in Latin (Nomina Anatomica), explained by the printed descriptions and illustrations of human dissections published in 1543 in the seminal work “De humani corporis fabrica” (“The Fabric of the Human Body”) by Andreas Vesalius.
Diode laser technology in the treatment of hemorrhoid disease. Laser HemorrhoidoPlasty (LHP) – description of the method
Authors: Glinkowski Sławomir , Marcinkowska Daria
Published: April 2021

Hemorrhoids is one of the most common proctological diseases of the anal canal. In the guidelines presented in 2018 in „Diseases of the Colon & Rectum”, the American Society of Colon and Rectal Surgeons (ASCRS) hasn’t specified laser techniques as a method of treatment. The first attempts of laser trail in hemorrhoidal treatment were made at the end of the 70s by using laser CO2 instead of scalpel. Nowadays one of the newest devices is Leonardo laser which emits fan-shaped movement of 1470 nm length. It enabled the development of laser hemorrhoidoplasty technique (LHP). The advantage of this procedure is decrease of hemorrhoidal plexus by obliteration of hemorrhoidal vessels leading to their fibrosis. It reclaims almost anatomical architecture of anal canal without a necessity to excise the extended hemorrhoids. Development of the connective tissue fibers guarantees adequate adhesion of mucosa to the underlying tissue which prevents the recurrence of the disease, especially the ones connected with prolapsing of hemorrhoids. The article contains a description of the method recommended by the manufacturer of Leonardo laser with the autors’ modifications developed on the basis of their own experience.
Anal abscess – a trivial disease or a serious one?
Authors: Kołodziejczak Małgorzata , Ciesielski Przemysław
Published: April 2021

A patient who reports to the hospital due to anal abscess is often treated as not seriously ill, although in about 40% of cases, abscess may initiate anal fistula development, and the one that is not or insufficiently emptied, may also cause septic complications that directly threaten patient’s life. The majority of inflammatory diseases in the rectum, including abscesses and anal fistulae, are a growing infection in the anal crypts. In recent years, a large group of patients with rectal abscesses have been patients with inflammatory bowel diseases, as well as immunocompromised patients, e.g. in the course of HIV infection. The anal abscess in any case should be urgently treated by its opening and drainage. The majority of patients with rectal abscesses should be admitted to the hospital and operated in the operating block, in adequate anesthesia (regional or general). The article discusses recommendations for the opening of low and high abscesses, postoperative management and possible complications associated with this disease and its inappropriate treatment. An abscess of the anus, generally considered a trivial disease, treated inappropriately, can cause serious complications.
Peripheral blood inflammatory parameters in patients with colorectal cancer
Authors: Nycz Michał , Kropieniewicz Jakub , Suliga Kamil , Zawadzki Tomasz , Opiłka Mieszko Norbert , Lorenc Zbigniew
Published: April 2021

Introduction. Colorectal cancer is the third most common cancer worldwide. The introduction of novel diagnostic and treatment methods has resulted in decreasing mortality rates; however, an increase in morbidity is observed. Severe inflammation plays an important role in many aspects associated with carcinogenesis. Neoplasia and inflammatory response are mutually related. Aim. The aim of the study was to evaluate the association between preoperative serum C-reactive protein levels and total leukocyte count in colorectal cancer patients in comparison with postoperative histopathological findings depending on whether there was neoplastic infiltration of the local adipose tissue or not. Material and methods. The study population included 50 patients with colon cancer. Exclusion criteria were distant metastases, neoadjuvant therapy and a past history of cancer diagnosis. Blood findings were compared with histopathology. Patients were divided into two groups – with and without neoplastic infiltration of fat tissue in histopathology. Results. Serum C-reactive protein levels were evaluated in all patients. The tested indicator was higher in the group with infiltration, but was not statistically significant. Additionally, the WBC count was normal in both groups, but it was lower in the group with infiltration, and the result was statistically significant. Conclusions. C-reactive protein level and total leukocyte count can be a helpful and supportive marker in staging in colorectal cancer patients. Owing to the wide availability and low cost of the above mentioned blood tests, they may be easily performed in daily medical practice. The decrease in the total leukocyte count was proportional with higher cancer stage; therefore, it needs to be further investigated.
«РОКСОЛАНІЯ» СЕБАСТЬЯНА КЛЕНОВИЧА ТА ОСТРОГ
Authors: Миненко Юрій
Published: April 2021

Стаття присвячена аналізу «Роксоланії» (1584) Себастьяна Кленовича. В описі міст Русі автор ігнорує Острог попри те, що на той час він був великим центром української культури. Уже 7 років діяла Острозька академія, що була заснована 1576 року. Вчений В. Шевчук припускає, що причиною цього є відсутність серед навчальних предметів закладу латинської мови. Сучасні дослідження доводять, що латинську мову в академії вивчали. В описі мешканців Львова Кленович негативно описав євреїв, звинувативши їх у нечистоті і лихварстві. На початку ХVI століття в Острозі сформувалася велика єврейська громада. Тут діяла Велика синагога і вища талмудична школа (єшибот). Саме Острог у цей час став головним центром іудейства Волині. Тож особиста неприязнь до єврейської національності була справжньою причиною, чому Кленович називає менш значимі на той час міста, але не згадує Острог.
V.V.STASOV VE RUS EPOSU KÖKENİ TARTIŞMALARI
Authors: Özer Yerke
Published: April 2021

У статті розглядається перше застосування в Росії теорії міграції, яке займає важливе місце в історії фольклористики і яке на Заході відоме як теорія Теодора Бенфея. Розглядається серія статей про епос, яка була опублікована в часописі «Вестник Европы» між 1868-1870 рр. І була першим прикладом порівняльногодослідження В.В. Стасова, першого представника цієї теорії в Росії. Незважаючи на різноманітні дискусії та різні думки, це дослідження, що стосується російського епосу та витоків історії, проклало шлях для порівняльної роботи в галузі особливо російського та східного епосу. Стаття також включає аналіз творчостіВ.В. Стасова та її наслідки для фольклористики цього періоду.
Compreensão e interpretação
Authors: Charaudeau Patrick
Published: April 2021

Quando se fala de interpretação, é obrigatório para toda disciplina referir-se a hermenêutica no campo da filosofia. Mas meu proposto não é fazer um análise filosófico. É somente fazer um percurso do que diz a discussão hermenêutica para depois tentar retomar essa questão no âmbito das ciências da linguagem, com o objetivo de fornecer uma perspectiva discursiva.