bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGGUNAAN METODE DEMONTRASI UNTUK MENINGKATKAN PRESTASI BELAJAR MATEMATIKA SISWA KELAS I B SDN 33 MATARAM
Authors: Siswati Siswati
Published: April 2023

Pencapaian hasil belajar siswa kelas I.B di SDN 33 Mataram, pada mata pelajaran Matematika masi berada dibawah KKM hal ini di karenakan metode yang digunakan belum tepat sehingga siswa hanya pasif dalam pembelajaran. Kreatifitas siswa dalam proses pembelajaran kurang karena dalam penyampaian guru bersifat monoton dan tanpa arah. Dari latar belakang diatas maka rumusan masalahnya “apakah metode Demonstrasi dalam pembelajaran Matematika tentang satuan waktu dapat meningkatkan prestasi belajar siswa kelas I.B SDN 33 Mataram Tahun Pelajaran 2021/2022” Jenis penelitian ini adalah penelitian tindakan kelas yang mencakup tahap perencanaan, tindakan, peaksanaan, observasi, evaluasi dan refleksi dengan melibatkan siswa kelas I.B sebagai subyek dan seorang guru sebagai teman sejawat/observer dan penelitian ini dilaksanakan dalam 2 siklus. Dengn menggunakan metode demonstrasi merupakan metode pembelajaran yang dapat meningkatkan kemampuan berpikir siswa untuk memecahkan masalah’ Terbukti dari peningkatan yang terjadi pada tiap siklus rata-rata prosentase pada pra siklus hasil tes 57% meningkat pada siklus I. 75% dan porsentasi pada siklus II meningakat jadi 90% dengan keaktifan siswa 100%. Metode demonstrasi dapat meningkatkan kompetensi siswa kelas I.B SDN 33 Mataram Tahun Pelajaran 2021/2022.
Spor Bilimleri Bölümlerine Merkezi Yerleştirme ile Kayıt Olan Üniversite Öğrencilerinin Spora İlişkin Tutumları
Authors: Akpınar Kocakulak Neşe , Özdemir Nurgül
Published: April 2023

Bu çalışmada merkezi yerleştirme yoluyla Egzersiz ve Spor Bilimleri Bölümüne yerleşmiş ve bölüm müfredatında uygulamalı eğitim alan öğrencilerin spora karşı tutumlarının incelenmesi amaçlanmıştır. Araştırma Egzersiz ve Spor Bilimleri Bölümü öğrencilerinin spora ilişkin tutum düzeylerini betimlemesi bakımından, nicel veri toplama tekniğinin kullanıldığı tarama modelinde betimsel bir çalışmadır. Çalışma İzmir Demokrasi Üniversitesi Sağlık Bilimleri Fakültesi, Egzersiz ve Spor Bilimleri Bölümünde öğrenim görmekte olan 147 öğrenciyi kapsamaktadır. Araştırmada katılımcıların spora ilişkin tutum düzeylerini belirlemek için Şentürk (2015) tarafından geliştirilen Spora Yönelik Tutum Ölçeği kullanılmıştır. Ölçek, 5’li likert tipinde spora ilgi duyma, sporla yaşama, aktif spor yapma olmak üzere üç alt boyuttan oluşmuştur. Ölçeğin Cronbach Alpha güvenirlik katsayısı r=.97 olarak bulunmuştur. Araştırmada ayrıca kişisel bilgilerin toplanmasında araştırmacılar tarafından düzenlenen kişisel bilgi formu kullanılmıştır. Araştırma verileri SPSS 26.00 paket programında analiz edilmiştir. Verilerin analizinde betimleyici istatistikler (frekans, yüzde, aritmetik ortalama, standart sapma) bağımsız gruplarda t-testi, tek yönlü varyans analizi testi kullanılmıştır. Araştırma sonucunda Egzersiz ve Spor Bilimleri Bölümü öğrencilerinin spora ilişkin tutumlarının orta düzeyde olduğu; tutumların cinsiyete, barınma durumuna, ekonomik duruma göre farklı olmadığı ve lisanslı spor yapma durumuna, sınıf değişkenine göre ise spora yönelik tutumlar arasında fark bulunduğu görülmüştür. Sonuç olarak, tercihle Egzersiz ve Spor Bilimleri Bölümüne yerleştirilen öğrencilerin spora yönelik tutumlarının olumlu olduğu, bu olumlu tutumun meslek olarak yönelimden kaynaklanabileceğini düşündürmektedir.
Understanding the experiences of caregivers of HIV-exposed children under five: A phenomenological inquiry
Authors: Hayati Happy , Nurhaeni Nani , Wanda Dessie , Nuraidah Nuraidah
Published: April 2023

Background: Children born to mothers with HIV require special care from the womb to the postnatal period, and caregivers involved in their care face several challenges.
Objective: This study aimed to explore caregivers’ experiences providing care for HIV-exposed children under five.
Methods: This study employed a phenomenological approach. Ten caregivers of HIV-exposed children living in Jakarta, Indonesia, were selected using snowball techniques. Online in-depth interviews were conducted to collect data from September 2021 to July 2022, and thematic analysis using Colaizzi’s method was performed for data analysis.
Results: The study involved ten caregivers (nine females and one male) aged between 23 and 42 years. Seven of them were mothers who tested HIV-positive, while one was an adoptive father, one was a mother’s sister, and one was an aunt of HIV-exposed children. The majority of them were housewives and had a low educational background. Three themes were generated: (i) disease-transmission foreboding, (ii) prejudice against mothers and children exposed to HIV, and (iii) seeking support.
Conclusion: Caring for HIV-exposed children poses emotional and physical challenges for caregivers, necessitating support from health professionals and peer groups. Nurses play essential roles in improving caregiver well-being and supporting optimal growth and development in HIV-exposed children under five by designing intervention programs. Furthermore, to enhance home-based HIV care in Indonesia, the government must implement social interventions that target families with limited resources.
PENGGUNAAN APLIKASI TIK TOK (VERSI TERBARU) DAN KREATIVITAS ANAK
Authors: Buana Tri , Maharani Dwi
Published: April 2023

Penelitian ini berjudul “Penggunaan Aplikasi Tik Tok (Versi Terbaru) Dan Kreativitas Anak”. Tujuan dari penelitian ini adalah mengetahui daya kreativitas anak usia 8-12 tahun. Media isosial tik tok adalah sebuah jaringan sosial dan platform video musik Tiongkok yang diluncurkan pada September 2016. Kreativitas mengacu pada kemampuan yang menandai ciriciri seorang kreatif. Aplikasi tersebut membolehkan para pemakai untuk membuat video musik pendek mereka sendiriTeori yang digunakan pada penelitian ini yaitu teori Sosial Kognitif yang dikembangkan oleh Albert Bandura dan Implementasi Teori Kreativitas yang dikembangkan oleh Wallas. Metode penelitian yang digunakan pada penelitian ini adalah metode kualitatif dengan pendekatan deskriptif, menggunakan metode pengumpulan data dengan cara wawancara, observasi serta dokumentasi. Lokasi penelitian ini terletak di Jalan Jendral Ahmad Yani No.1375, Plaju, Sumatera Selatan. Informan pada penelitian ini terdiri dari informan utama dan informan pendukung. Informan utama pada penelitian ini adalah Sakha Ibadil Qiram dan Naura sebagai Konten Kreator, beserta Khanaya Azzahra Salsabilla sebagai pengguna aktif aplikasi Tik Tok. Berdasarkan hasil penelitian, disimpulkan bahwa tik tok sebagai salah satu rekreasi dan salah satu media anak untuk mengeksplore diri dan berpikir kreatif dan sebagai penghibur anak.
PENGARUH KOMUNIKASI ANTAR PRIBADI TERHADAP MOTIVASI RELIGIUS ANGGOTA ROHIS SMK NEGERI 3 PALEMBANG
Authors: Rosseno Paray Muhammad , Isnawijayani Isnawijayani
Published: April 2023

This thesis entitled The Effect of Interpersonal Communication on Religious Motivation of Rohis Members of SMK Negeri 3 Palembang. The formulation of this problem is how much "The Effect of Interpersonal Communication on Religious Motivation of Rohis Members of SMK Negeri 3 Palembang", while the purpose of this study is to determine how much influence of interpersonal communication on religious motivation of Rohis members of SMK Negeri 3 Palembang. The method used in this research is quantitative by using a questionnaire, with the aim that researchers can immediately retrieve the data. The total population is 30 people, the total sample is 30 members of Rohis SMK Negeri 3 Palembang. The data analysis technique used in this research is to find regression by testing the hypothesis through the t distribution. The results of the study explains that the effect of interpersonal communication has a positive effect on Rohis members of SMK Negeri 3 Palembang on religious motivation of Rohis members of SMK Negeri 3 Palembang.
INTERPRETASI DIRI SEORANG FEMALE DISK JOCKEY DI NEOPC CLUB AND LOUNGE PALEMBANG
Authors: Hati Pelangi Rembulan Permata , Wati Desy Misna
Published: April 2023

The purpose of this study was to find out how self-interpretation  of a female disk  jockey. The research method used is qualitative. The object of this study is the self interpretation   of a female disk jockey at NEOPC Club and Lounge Palembang. The subjects in this study who acted as a source of information were two women who became female disk jockeys, Head disk jockeys, and a visitor at NEOPC Club and Lounge Palembang. Data  collection  techniques  obtained through interview data, observation data, and documentation data. Data analysis techniques using descriptive qualitative methods. The results of this study can be concluded that female disk jockeys interpret themselves when performing on stage with  their performances and  the songs they play. They give a good impression to visitors, from the way they interact with visitors, other employees, to other fellow disk jockeys. All about themselves  will  be  an  assessment for visitors who watch their performance. Researchers also see other things behind the performance on the stage how the female disk jockey interacts with their environment that is different from where they work.
REPRESENTASI FOTO VENEZUELA CRISIS DI KALANGAN PEWARTA FOTO PALEMBANG
Authors: Kurniawan Agung , Maharani Dwi
Published: April 2023

The purpose of this study was to determine the meaning of the Venezuelan Crisis PhotoRepresentation dance among Palembang Photo Reporters. This research method is qualitative witha descriptive approach to interview, observation, documentation, literature study. Subjects in thisstudy consisted of actors and observers of the art of journalistic photography using Charles SandersPierce's semiotic theory as the theoretical basis of the research entitled Venezuelan Crisis photorepresentation among Palembang photo reporters. Judging from the meaning in the VenezuelaCrisis photo, it is a journalistic photo with the theme of sports news containing a very strongmessage. The meaning of the photo of Venezuela Crisis, there is an allusion to the meaning impliedin it which contains the values and images of the riots in the city of Venezuela in crisis. Based onthe research results, it is concluded that the Venezuela Crisis photo is a photo with a strong messagemeaning to be conveyed to the public to win the world-level photography championship in the worldpress.
PENGGUNAAN MEDIA SOSIAL INSTAGRAM PADA AKUN @YHOOPHII_OFFICIAL SEBAGAI MEDIA KOMUNIKASI DENGAN PELANGGAN
Authors: Feroza Cindie Sya’bania , Misnawati Desy
Published: April 2023

This research entitled "Use of Instagram Social Media on @yhoophii_official Accountas a media of communication with customers". The purpose of this research is to find out how theuse of Instagram social media on the @yhoophii_official account as a media of communication withcustomers. Instagram is an application to share photos, videos, apply digital filters and share themto various network services including Instagram itself. The method used in this research is aqualitative method with a descriptive approach, using data collection methods with interviews,observation, and documentation. The theory used in this research is the theory of New Media byPierre Levy. The location of this research is located at Jalan Kapten Marzuki No. 528 C,Palembang, South Sumatera. Informants in this research consisted of key informants and supportinginformants. The key informant in this research is Sri Rahayu Widianti as the admin of the@yhoophii_official Instagram account. And two supporting informants in this research is Yoza DwiCahaya and Fitria Wulandari as a customers. The results of this research show that the@yhoophii_official account is used to share information about products, store operating hours, howto shop online, all things related to the Yhoophii Shop, and to become a media of communicationwith customers. Customers can interact by providing questions through the @yhoophii_officialaccount which will be answered by the admin.
EVENT SEBAGAI SARANA MEMPERERAT SOLIDARITAS KELOMPOK (STUDI DESKRIPTIF KUALITATIF PADA KOMUNITAS BYMAX BANYUASIN)
Authors: Habi Imam Idris , Wijayani Isna
Published: April 2023

The purpose of this research is to find out how event events can strengthen solidarityamong BYMAX Banyuasin Community members. The research method used is qualitative with adescriptive approach to interview, observation, documentation. The theory used in this study is theTheory of Social Relations. The subjects of the study were four members of Bymax Banyuasin, oneinformant, the general chairman, Vicky Mahendra, the second informant, the vice chairman, arifBudiman, the third informant, Ricky P.U, the secretary. The four informants, Erawadi's advisors,said that the location of the research was conducted at BYMAX Banyuasin Basecamp, which islocated at Jl. Mulya Agung is a gathering place for the BYMAX Banyuasin community. The resultsof this study show that social service activities were held because of the rampant Covid-19 pandemicin Indonesia. The lack of awareness of the Banyuasin community to use masks when traveling hasmade BYMAX Banyuasin Community members pioneer the movement to distribute street masks. Themembers raise funds from various circles. Funds or donations are channeled to buy masks andhandsanitizers and are distributed to the streets. several social service activities carried out by theBYMAX Banyuasin community. With this activity the solidarity of the community is alsostrengthened plus a sense of concern for the community that grows from the self-awareness of itsmembers to help society
Morphophysiological Parameters of Hard and Soft Wheat Genotypes Depending on Different Water Supply
Authors: Abdulbagiyeva S. , Mammadova S. , Zamanov A. , Ibrahimova I.
Published: April 2023

To determine drought tolerance of 10 wheat varieties (3 durum and 7 bread) differing in architectonics, the research was performed under normal and drought conditions. The reduction in the plant height due to cultivation conditions rather than genetic properties of the genotypes occurred because of the decreasing length of upper internodes by 0.47-9.51%. Structural components of the product were determined. The greatest reduction in above-ground dry biomass per unit of the field was detected in Barakatli 95 and Garagylchyg 2 genotypes. The amounts of pigments were determined to evaluate the level of the photosynthetic apparatus development, its physiological state, formation and accumulation potential of the product. The content of chlorophyll a, b and carotenoids was determined during the grain forming, milk ripening, and wax ripening phases. Green plastids were broken down and chlorophyll content decreased under drought. Chlorophyll a content decreased more sharply compared with chlorophyll b. Chlorophyll a content decreased more sharply in all phases in the durum variety Barakatli 95 (during the phases, respectively, 19.7; 16.6 and 35.6%) and bread variety Gyrmyzy gul 1 (21.9; 15.3; 39.5%). Chlorophyll b amount decreased less in the durum variety Tartar (11.0; 7.30; 14.2%) and bread variety 4th FEFWSN-50 (4.83; 10.8; 9.20%). Amounts of the photosynthetic pigments were determined in various regions (Gobustan and Jalilabad Regional Experimental Stations). Chlorophyll a content decreased more in the Gyrmyzy gul 1 and Garagylchyg 2 varieties (in Gobustan: 2.302 and 2.979 mg/g fresh weight) in Jalilabad: 2.096 and 2.737 mg/g fresh weight) under rainfed conditions. Drought had a relatively less impact on chlorophyll a content in the Azamatli 95 and Gobustan varieties. Chlorophyll b content ranged from 0.033 to 2.398 mg/g fresh weight in Gobustan and from 0.057 to 2.175 mg/g fresh weight in Jalilabad, whereas the content of did not decrease.
Neuro-Muscular Block, Its Reversion and Monitoring (Review Article)
Authors: Chyngyshova Zh. , Raimbekov Zh. , Turdiev U. , Nazarbekov D.
Published: April 2023

Muscle relaxants are often given during general anesthesia to facilitate endotracheal intubation. However, lingering effects after the end of anesthesia can lead to respiratory failure in the intensive care unit. Strategies to reduce these adverse events include monitoring for neuromuscular blockade, the use of short-acting drugs, and active pharmacological withdrawal before extubation. We analyzed the medical literature on neuromuscular block, its reversal and monitoring in neuromuscular block.
Focal Temporal Lobe Epilepsy, Analysis of Clinical and Anamnestic Data and Evaluation of the Effectiveness of Anti-epileptic Therapy
Authors: Batyrov M.
Published: April 2023

We studied clinical and anamnestic data and the effectiveness of anticonvulsants in 31 patients with focal temporal lobe epilepsy. Seizures in the form of isolated aura and non-motor seizures dominated at the onset of the disease (77%), which were regarded as non-epileptic paroxysms, and most patients (80%) sought medical help later than 6 months. Among non-motor seizures, it is worth noting the inhibition of behavioral reactions (22%), vegetative (42%) and mental seizures (13%). Automatisms was found in 18 (58%) patients, focal motor seizures in the form of a unilateral dystonic seizure in 9 (29%) patients, and secondary generalized seizures were noted in 19 (61%) patients. The use of modern antiepileptic drugs in combination was effective in 42%.
Perancangan Animasi Edukasi Minum Susu ‘Milkaya’ dengan Tema Kebudayaan Reog Ponorogo
Authors: Widyasari Widyasari , Wulandari Sri , Utomo Samuel Rihi Hadi , Shabina Sharah , Ramadhani Brilliant Firdaus
Published: April 2023

AbstrakDampak stunting tidak hanya berpengaruh dalam jangka pendek untuk anak-anak, tetapi apabila tidak ditangani maka jangka panjangnya dapat mempengaruhi produktivitas ketika anak beranjak dewasa dan kesulitan bersaing dalam dunia kerja. Minum susu dapat menjadi solusi terkait permasalahan stunting, membantu pemerintah dalam menekan angka kasus stanting di Indonesia. Melihat akan hal ini dibutuhkan edukasi minum susu untuk anak-anak. Penelitian ini berusaha melakukan eksplorasi penggunaan animasi sebagai edukasi minum susu untuk anak-anak usia 7-12 tahun, sekaligus untuk melestarikan kebudayaan lokal Reog Ponorogo dan promosi produk susu lokal Milkaya. Metode penelitian kualitatif dengan tahapan perancangan dari pra-produksi, produksi hingga pasca produksi dapat menghasilkan video animasi edukasi minum susu Milkaya yang tidak hanya menarik untuk anak-anak, tetapi proses penyampaian pesan edukasinya pun dapat berlangsung dengan mudah. Tema perjuangan dari kebudayaan Reog Ponorogo, memberikan semangat perjuangan yang sama untuk menekan angka kasus stunting di Indonesia dengan minum susu Milkaya dan perjuangan untuk melestarikan kebudayaan lokal Indonesia di tengah gelombang besar globalisasi. Kata Kunci: animasi, edukasi, minum susu, Milkaya, Reog Ponorogo AbstractThe impact of stunting does not only affect children in the short term, but if it is not handled in the long term, it can affect productivity when children grow up and have difficulty competing in the world of work. Drinking milk can be a solution to the problem of stunting, helping the government reduce the number of stunting cases in Indonesia. Seeing this, education about drinking milk is needed for children. This study seeks to explore the use of animation as education to drink milk for children aged 7-12 years, as well as to preserve the local culture of Reog Ponorogo and promote local milk products, Milkaya. Qualitative research methods with design stages from pre-production and production to post-production can produce animated educational videos of drinking Milkaya milk which is interesting for children. The process of delivering educational messages can also take place quickly. The theme of struggle from the cultural of Reog Ponorogo provides the same spirit of struggle to reduce the number of stunting cases in Indonesia by drinking Milkaya milk and the struggle to preserve local Indonesian culture in the midle of globalization wive. Keywords: animation, education, drinking milk, Milkaya, Reog Ponorogo
PHP web-based mathematics learning application: An analysis of student responses
Authors: Harun Muhammad , Ratnaningsih Nani , Supratman Supratman
Published: April 2023

This study aims to analyze and describe students' responses to PHP web-based mathematics learning applications. The research method used is quantitative descriptive. The research sample were 63 students of class X at SMK Al-Ihya Selajambe, Kuningan Jawa Barat. The research instrument uses a student response questionnaire. Data analysis used is quantitative descriptive analysis in the form of percentages. The results of the data in the form of percentages are described using response interpretation criteria. Based on the results of the study, PHP web-based mathematics learning applications gets a percentage of responses 87,04 % for the layout aspect which was in the very good response interpretation criteria, 85,71 % for the display aspect which was in the very good response interpretation criteria, and 88,94 % for the function aspect which was in the very good response interpretation criteria. Overall, the PHP web-based mathematics learning application gets a percentage of responses 87,70% which was in the very good response interpretation criteria. It can be concluded that PHP web-based mathematics learning applications get a very good response from students to use in learning.
Modelling of the safe traffic conditions of the intersection with nerby railway tracks
Authors:   National University of Water and Environmental Engineering, Khitrov Ihor
Published: April 2023

Highway are extremely important for the economic development of Ukraine. Road intersections are the critical part of the road network in terms of capacity, service level and safety. This is a place where oppose traf-fic flows are constantly changing and thus changing the traffic situation. To study the safety of traffic, we have chosen the problematic intersection of the city of Dubno, the intersec-tion of Mostova and Kremenetska streets, which are main roads with intensive round-the-clock traffic flow. The main feature of this intersection is the proximity location of the railway crossing. The PTV Vissim software was used to simulate the driving conditions of this intersection. As the initial data for modeling the intersection were used: observations of traffic flows, the number of vehicles, their distribution at the intersection, accumulation at a prohibited traffic light signal while waiting for a train. It is established, that the distribution of traffic flows in the main direction is 73,6%, while the left turn is made by 26,4%. The intersection is characterized by the 24-hour saturated traffic flow with frequent traffic stopping of vehicles of the main direction, which is due to the movement of trains. From the point view of the organization of traffic safety, the following road situations are observed: difficult driving; non-compliance with the trajectory of turning vehicles due to the overall features of transport or the choice of an insufficient trajectory of changing the direction of movement; the choice of an insufficient rounding radius for turning right (especially observed at night); the difficulty of performing a left turn, when the signal of the main direction railway crossing is prohibited. In order to speed up the passage of the intersection by vehicles, reduce the risk of traffic accidents while wait-ing for the train to pass, the convenience of crossing the road by pedestrians should be provided for: 1. Two traffic lanes in the main direction; 2. Pedestrian crossing of the main direction; 3. Marking traffic by traffic lanes; 4. Arrangement of modern lighting. Thus, the proposed measures will improve the efficiency and safety of crossing intersection, especially in the case of nearby railway tracks. The simulated traffic conditions for passing the intersection by vehicles indicate a positive trend, namely: a decrease in the delay time for passing the intersection when making a left turn by 50.6% and an increase in the overall speed of traffic by 24.3%. Keywords: crossroads, vehicles, railway tracks, traffic flow, safety, modeling.
Еxperimental tests of a diesel car operating on diesel fuel and diesel biofuel
Authors:   National Transport University, Kovbasenko Serhii , Bugryk Oleksii ,   SE “State Road Transport Research Institute"
Published: April 2023

Realizing the problems that constantly accompany the use of road transport, against the background of the increasing shortage of liquid fuels of petroleum origin in Ukraine and other countries, serious attention has long been paid to the use of alternative, more environmentally friendly types of motor fuels, which include biofuels, natural gas and hydrogen. At the same time, the issue of reducing environmental pollution by road transport is an important component of the general environmental problem, the severity of which increases every year. With the significant growth of food industry facilities, there is a need to dispose of food products, namely food fats, which create a negative impact on the environment. Therefore, a possible way to solve the problem of disposal of edible fats can be their processing into diesel biofuel. The use of biodiesel fuel from recycled food fat waste does not require significant changes in the engine design, at the same time, it will allow to expand the fuel base of diesel vehicles and reduce their harmful impact on the environment. The article presents the results of bench tests of a passenger car with a diesel engine when operating on diesel fuel and diesel biofuel, namely: emissions of harmful substances and fuel consumption by cycle, comparative load characteristics of a diesel engine in a passenger car. The possibility of using diesel biofuel from recycled food fat waste in diesel engines of modern cars has been confirmed. The conducted studies proved the reduction of the total mass emissions, reduced to carbon monoxide emissions, for work on diesel biofuel. Keywords: diesel, diesel biofuel, passenger car, experimental tests, fuel consumption, harmful emissions.
Dynamics of the suspension part of a wheeled vehicle and motion stability
Authors:   Hetman Petro Sahaidachny National Military Academy, Sokil Bohdan , Sokil Maria ,   Lviv Polytechnic National University, Romanchuk Yaroslav ,   Hetman Petro Sahaidachny National Military Academy
Published: April 2023

The article investigates the influence of longitudinal-angular vibrations of the sprung mass of wheeled vehicles (WV) with nonlinear characteristics of the suspension system and kinematic parameters of move-ment along the curved sections of the road on the stability of WV. The main results of the work were obtained using the equations of kinetic statics, a mathematical model of relative nonlinear longitudinal-angular oscillations of the sprung mass (SM), based on the analysis of the quantitative and qualitative influence of the main force parameters of the suspension system (SS) and the determining parameters of longitudinal-angular oscillations of the SM on the level of interaction of the tires with the road coating. The critical speed of steady movement of the vehicle is determined as a function of the geometric and power parameters of the SS, the characteristics of the road surface, and the amplitude of longitudinal and angular oscillations. The numerical analysis of obtained ratios has shown that the critical values of steady motion speed for the skidding of the WV along the curved sections of the road are different: a) a larger value of the amplitude of SM oscillations corresponds to a smaller value of the critical speed of steady motion; b) it is significantly overestimated if the longitudinal and angular fluctuations of the sprung mass are not taken into account; c) the value is bigger for WV with the progressive force characteristic of the shock absorbers at small amplitudes of oscillations compared to the linear force characteristic (under the condition of equality of static deformation), and vice versa for the “large” ones; d) the value for the regressive force characteristic of elastic shock absorbers at small amplitudes of oscillations is smaller than for the linear characteristic of the shock absorbers, and the opposite for the “large” ones; e) the critical value of the speed of steady motion is bigger for the progressive characteristic of elastic shock absorbers at larger values of the static deformation of the SS and, on the contrary, it is smaller for the regressive one. The obtained results can be used for the designing or modernization of suspensions and well as a basis for development of a new software product for the controlled suspension systems. They coincide in the limiting case with those known in the scientific literature, which confirms their credibility. Keywords: Oscillations of sprung mass, amplitude, frequency, critical speed of steady motion.
Overview of information and communication technologies and vehicle monitoring systems and analysis of their possibilities for the formation and implementation of innovative technologies for maintenance and repair of vehicles
Authors:   National Transport University, Biletskyi Volodymyr , Ivanushko Oleksandr , Loboda Andrii , Buhaichuk Oleksandr ,   National Transport University, Lovha Roman ,   “WebEye” (Ukraine)
Published: April 2023

Preventive maintenance is performed at fixed intervals based on pre-made statistical estimates of when a failure may occur or when a part may need to be replaced. Predictive maintenance is performed at unfixed intervals that are determined based on predictive estimates of when a failure may occur or when a part may need to be replaced. The predictive maintenance system is based on the automated collection and automated processing of all technical information necessary to predict the most optimal intervals. This possibility is provided by innovative information technologies for monitoring vehicles connected to the internet. An overview of the possibilities of infor-mation and communication technologies and monitoring systems in road transport, in particular, technologies connected to the Internet vehicles, which allow developing and implementing innovative maintenance and repair technologies, was conducted. The possibilities of connecting “unconnected” cars to the Internet are considered and given. The potential possibilities of a gradual transition from a planned and preventive maintenance system to a “predictive” system, which is based on the constant monitoring of the processes of changing diagnostic parameters and related parameters characterizing the modes and conditions of operation of the engine, transmission and the vehicle as a whole, are analyzed. A review of the current state of development, implementation and application of service systems “on operational need” and forecasting processes of changing the technical condition and forecasting the possibility of malfunctions for their prevention in motor vehicle enterprises was carried out. The main conclusions are drawn based on the analysis of informational materials and work experience of such companies as Stratio Automotive, Pitstop Connect, Web Eye, as well as BOSCH, LAUNCH, and Electronic Team Inc. Keywords: innovative technology, information technology, vehicle monitoring system, connected vehicle, remote diagnosis, real-time monitoring of diagnostic parameters, preventive maintenance system, predictive maintenance system, prediction of changes in technical condition, automated system maintenance planning, vehicle location monitoring.
Modeling the political choice of public health insurance
Authors: Fall Abdou Khadre Dit Jadir
Published: April 2023

This article aimed to study the choice that people have to make between two health insurance systems in a monopolistic scheme. The first health insurance system proposes a uniform contribution level and the second one proposes a contribution level that is proportional to the probability of getting sick. The individuals differ (or are distinguished) by their number in a group, the net income, the contribution level, the probability of getting sick, and health cost. Two kinds of voting models using the welfare function are used; a direct vote that involves a size effect and a probabilistic vote that involves a bias in favor of one system. The results, according to theoretical models, indicate that a uniform contribution level is adopted by high-risk individuals and also if wealth and illness are strongly negatively correlated. However, when wealth and illness are not correlated or are poorly correlated, a contribution proportional to the probability of getting sick is adopted. These results were explained by the fact that the loss of wellbeing for low-income and sick people is more important.
Formalin-free fixation and xylene-free tissue processing preserves cell-hydrogel interactions for histological evaluation of 3D calcium alginate tissue engineered constructs
Authors: Da Silva Iran Augusto , Gvazava Nika , Putra Wendi Indra , Guinea Rodrigo , García Giménez Francisco , Stegmayr John , Klementieva Oxana , Wagner Darcy E.
Published: April 2023

Histological evaluation of tissue-engineered products, including hydrogels for cellular encapsulation, is a critical and invaluable tool for assessing the product across multiple stages of its lifecycle from manufacture to implantation. However, many tissue-engineered products are comprised of polymers and hydrogels which are not optimized for use with conventional methods of tissue fixation and histological processing. Routine histology utilizes a combination of chemical fixatives, such as formaldehyde, and solvents such as xylene which have been optimized for use with native biological tissues due to their high protein and lipid content. Previous work has highlighted the challenges associated with processing hydrogels for routine histology due to their high water content and lack of diverse chemical moieties amenable for tissue fixation with traditional fixatives. Thus, hydrogel-based tissue engineering products are prone to histological artifacts during their validation which can lead to challenges in correctly interpreting results. In addition, chemicals used in conventional histological approaches are associated with significant health and environmental concerns due to their toxicity and there is thus an urgent need to identify suitable replacements. Here we use a multifactorial design of experiments approach to identify processing parameters capable of preserving cell-biomaterial interactions in a prototypical hydrogel system: ionically crosslinked calcium alginate. We identify a formalin free fixative which better retains cell-biomaterial interactions and calcium alginate hydrogel integrity as compared to the state-of-the-art formalin-based approaches. In addition, we demonstrate that this approach is compatible with a diversity of manufacturing techniques used to fabricate calcium alginate-based scaffolds for tissue engineering and cell therapy, including histological evaluation of cellular encapsulation in 3D tubes and thin tissue engineering scaffolds (∼50 μm). Furthermore, we show that formalin-free fixation can be used to retain cell-biomaterial interactions and hydrogel architecture in hybrid alginate-gelatin based scaffolds for use with histology and scanning electron microscopy. Taken together, these findings are a significant step forward towards improving histological evaluation of ionically crosslinked calcium alginate hydrogels and help make their validation less toxic, thus more environmentally friendly and sustainable.
Synthesis, band gap structure and third order non-linear optical properties of zinc tungsten oxide nanocomposite using a single CW laser beam
Authors: Jalili Zahra , Koushki Ehsan , Ehsanian Amir Hossein , Tayebee Reza , Maleki Behrooz
Published: April 2023

In this study, a composite of zinc tungsten oxide nanoparticles (W-ZnO NPs) has been synthesized via mixing Na2WO4 and zinc acetate in water, followed by dropwise addition of NaOH. The synthesized W-ZnO NPs were characterized using measurement methods such as XRD, dynamic light scattering (DLS), Scanning electron microscopy (SEM) and UV-Vis. Also, the results were compared with the pure synthesized ZnO and WO3 NPs. Non-linear optical properties of the synthesized composite were measured using the Z-scan technique with a continuous wave Nd-Yag laser. The negative non-linear absorption coefficient of the components was obtained which indicates that the saturation absorption occurred in this composite. In comparison with pure ZnO NPs, non-linear absorption decreases which can be attributed to the negligible optical response of WO3 structures. Also, the negative value of the close aperture Z-scan curve shows that the thermal lensing effect is the main reason for the third-order non-linear refraction.
A case report: Severe disseminated infection caused by Strongyloides stercoralis in an immunocompromised patient by metagenomic next-generation sequencing
Authors: Xu Qinfu , Xi Xiaotong , Feng Dan , Sang Qian , Sheng Yanbing , Ding Ran , Xu Aiguo
Published: April 2023

Background

Strongyloides stercoralis (S. stercoralis) is a nematode that is widely distributed in the tropical and subtropical regions of the world and which can cause severe disseminated infection in immunocompromised individuals. However, strongyloidiasis, the disease caused by S. stercoralis, is difficult to diagnose because of its non-specific clinical presentation and the inadequate performance of conventional diagnostic methods.

Case description

We report the case of a 75-year-old male patient with severe disseminated infection caused by S. stercoralis. The patient had a medical history of seasonal bronchitis and, as a consequence, had taken prednisone for many years. Initial clinical tests failed to detect any pathogens, but metagenomic next-generation sequencing (mNGS) resulted in the identification of S. stercoralis in the patient’s bronchoalveolar lavage fluid (BALF) and blood. Subsequently, routine testing repeatedly detected nematode larvae in the patient’s stool and sputum. Through a combination of mNGS results and clinical symptoms, the patient was finally diagnosed with severe disseminated infection caused by S. stercoralis.

Conclusion

The clinical manifestations of disease caused by infection with S. stercoralis are not specific; therefore, early and accurate diagnosis is very important. mNGS can detect S. stercoralis even when it is present at only a low level. This case report supports the notion that mNGS is a valuable tool in the diagnosis of severe disseminated infections caused by S. stercoralis in immunocompromised patients.
Metabolic pathways that permit Mycobacterium avium subsp. hominissuis to transition to different environments encountered within the host during infection
Authors: Abukhalid Norah , Rojony Rajoana , Danelishvili Lia , Bermudez Luiz E.
Published: April 2023

Introduction

M. avium subsp. hominissuis (M. avium) is an intracellular, facultative bacterium known to colonize and infect the human host through ingestion or respiratory inhalation. The majority of pulmonary infections occur in association with pre- existing lung diseases, such as bronchiectasis, cystic fibrosis, or chronic obstructive pulmonary disease. M. avium is also acquired by the gastrointestinal route in immunocompromised individuals such as human immunodeficiency virus HIV-1 patients leading to disseminated disease. A hallmark of M. avium pulmonary infections is the ability of pathogen to form biofilms. In addition, M. avium can reside within granulomas of low oxygen and limited nutrient conditions while establishing a persistent niche through metabolic adaptations.

Methods

Bacterial metabolic pathways used by M. avium within the host environment, however, are poorly understood. In this study, we analyzed M. avium proteome with a focus on core metabolic pathways expressed in the anaerobic, biofilm and aerobic conditions and that can be used by the pathogen to transition from one environment to another.

Results

Overall, 3,715 common proteins were identified between all studied conditions and proteins with increased synthesis over the of the level of expression in aerobic condition were selected for analysis of in specific metabolic pathways. The data obtained from the M. avium proteome of biofilm phenotype demonstrates in enrichment of metabolic pathways involved in the fatty acid metabolism and biosynthesis of aromatic amino acid and cofactors. Here, we also highlight the importance of chloroalkene degradation pathway and anaerobic fermentationthat enhance during the transition of M. avium from aerobic to anaerobic condition. It was also found that the production of fumarate and succinate by MAV_0927, a conserved hypothetical protein, is essential for M. avium survival and for withstanding the stress condition in biofilm. In addition, the participation of regulatory genes/proteins such as the TetR family MAV_5151 appear to be necessary for M. avium survival under biofilm and anaerobic conditions.

Conclusion

Collectively, our data reveal important core metabolic pathways that M. avium utilize under different stress conditions that allow the pathogen to survive in diverse host environments.
Fungal dysbiosis facilitates inflammatory bowel disease by enhancing CD4+ T cell glutaminolysis
Authors: Yu Minhao , Ding Hui , Gong Shuai , Luo Yang , Lin Haiping , Mu Yifei , Li Hao , Li Xiaobo , Zhong Ming
Published: April 2023

The fungal microbiota is an important component of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation. However, how fungi regulate inflammatory bowel disease (IBD) is poorly understood. This study found that intestinal fungi regulate immune responses in IBD. Antibiotic-mediated depletion of fungi facilitated the development of IBD. Fungi greatly enhanced oxidative phosphorylation (OXPHOS) by enhancing glutaminolysis. Mechanistically, we found that fungi could activate the dectin-1-Syk- NF-κB signaling pathway to promote the expression of key enzymes and transporters involved in glutaminolysis. In summary, our findings reveal that fungal interactions in the human gut could be a promising therapeutic target for IBD.
Characterization of anti-erythrocyte and anti-platelet antibodies in hemolytic anemia and thrombocytopenia induced by Plasmodium spp. and Babesiaspp. infection in mice
Authors: Zhou Mo , Xie Jun , Kawase Osamu , Nishikawa Yoshifumi , Ji Shengwei , Zhu Shanyuan , Cao Shinuo , Xuan Xuenan
Published: April 2023

Introduction

Malaria and Babesiosis are acute zoonotic disease that caused by infection with the parasite in the phylum Apicomplexa. Severe anemia and thrombocytopenia are the most common hematological complication of malaria and babesiosis. However, the mechanisms involved have not been elucidated, and only a few researches focus on the possible role of anti-erythrocyte and anti-platelet antibodies.

Methods

In this study, the Plasmodium yoelii, P. chabaudi, Babesia microti and B. rodhaini infected SCID and ICR mice. The parasitemia, survival rate, platelet count, anti-platelet antibodies, and the level of IFN-γ and interleukin (IL) -10 was tested after infection. Furthermore, the P. yoelii, P. chabaudi, B. rodhaini and B. microti infected ICR mice were treated with artesunate and diminaze, the development of the anti-erythrocyte and anti-platelet antibodies in chronic stage were examined. At last, the murine red blood cell and platelet membrane proteins probed with auto-antibodies induced by P. yoelii, P. chabaudi, B. rodhaini, and B. microti infection were characterized by proteomic analysis.

Results and discussion

The high anti-platelet and anti-erythrocyte antibodies were detected in ICR mice after P. yoelii, P. chabaudi, B. rodhaini, and B. microti infection. Actin of murine erythrocyte and platelet is a common auto-antigen in Plasmodium and Babesia spp. infected mice. Our findings indicate that anti-erythrocyte and anti-platelet autoantibodies contribute to thrombocytopenia and anemia associated with Plasmodium spp. and Babesia spp. infection. This study will help to understand the mechanisms of malaria and babesiosis-related thrombocytopenia and hemolytic anemia.
Case report: An occult hepatitis B virus infection reactivation in an HIV/HCV coinfected patient during an immune reconstitution inflammatory syndrome
Authors: Zaltron Serena , Cambianica Anna , Di Gregorio Marco , Colangelo Cosimo , Storti Samuele , Tiecco Giorgio , Castelli Francesco , Quiros-Roldan Eugenia
Published: April 2023

The natural history of occult hepatitis B virus infection (OBI) and the mechanism involved in HBV reactivation are only partially understood. As regards people living with HIV (PLWH), HBV reactivation is estimated to occur with an incidence ratio of 0.019 cases per 100 person-year. Here we report the case of OBI reactivation in a HIV/HCV co-infected patient followed for 25 years at our Infectious Diseases Unit, but, unfortunately, lost to follow-up about 19 months after Direct-acting antivirals (DAAs) treatment. At re-engagement, blood tests showed high replication of plasmatic HIV-RNA along with severe immunosuppression and normal levels of liver enzymes. However, 3 months after ART reintroduction, an immune reconstitution inflammatory syndrome (IRIS) was diagnosed with high detectable HBV-DNA load and transaminase elevation. Our case report shows how the balance between the virus and the host immune system is quite a dynamic process that might significantly impact the course of the disease. The aim of this case report is to bring to the attention of physicians that, although OBI reactivation is a rather rare occurrence, even amongst PLWH, its potential consequences compel to a high alertness on the matter. Therefore, especially in patients with an impaired immune system and on a tenofovir or lamivudine-sparing regimen, HBV serological and virological markers should always be strictly monitored, even in the absence of a hepatitis flare.
The unembodied metaphor: comprehension and production of tactile metaphors without somatosensation
Authors: Phillips Jacob B. , Grenoble Lenore A. , Mason Peggy
Published: April 2023

Introduction

Proposals for embodied metaphor and embodied cognition have suggested abstract concepts are understood indirectly through the simulation of previous sensory experiences in a different domain. While exceptions have been observed for sensory deficits and impairments that are common, such as vision and audition, it is commonly assumed that somatosensation (proprioception, haptic touch, pain, pressure, temperature, etc.) is fundamental for the comprehension of production of sensory metaphors and much abstract thought in general. In this way, our past sensory experiences are critical to our understanding not just of the world around us but also of our sense of selves. This would suggest that Kim, who was born without somatosensation, would have difficulty understanding, using, or even thinking about many abstract concepts typically linked to different sensory experiences through metaphor, including a creation of a sense of self.

Methods

To examine her comprehension of sensory metaphors, Kim was asked to select the best sensory idiomatic expression given its context. Her friends and family as well as a representative sample of individuals online were recruited to complete the survey as controls. Additionally, we transcribed and analyzed six hours of unprompted speech to determine if Kim spontaneously uses somatosensory metaphors appropriately.

Results

Results from the idiomatic expression survey indicate that Kim performs as well as controls despite lacking any previous direct sensory experiences of these concepts. Analysis of the spontaneous speech highlights that Kim appropriately uses tactile expressions in both their concrete sensory and abstract metaphorical meanings.

Discussion

Taken together, these two studies demonstrate that what is lost in sensory experiences can be made up in linguistic experiences, as Kim's understanding of tactile words was acquired in the complete absence of somatosensory experiences. This study demonstrates that individuals can comprehend and use tactile language and metaphor without recruiting past somatosensory experiences, and thus challenges a strong definition of embodied cognition which requires sensory simulations in language comprehension and abstract thought.