bluuebunny/crossref_metadata_2025 huggingface dataset:
THE IMPLEMENTATION OF GOOD ENVIRONMENTAL GOVERNANCE IN WASTE MANAGEMENT
Authors: Ramadhiyanti Triyani
Published: January 2025

Waste is a national problem in Indonesia that has not found an optimal solution and tends to get worse. Effective waste management for environmental preservation and extinction is one of the principles of good environmental governance. An important part of good governance is collaboration between the private sector and the community to achieve effective, efficient, and appropriate waste management. This study aims to assess the implementation of waste management in Tuah Karya Village. This study uses a qualitative descriptive method with data collection techniques including observation, interviews, and documentation. The results of the study show the implementation of Good Environmental Governance in waste management in Pekanbaru, with a focus on the steps that have been taken by local governments to build effective waste management in their respective regions. Several areas in Pekanbaru have implemented good waste management practices, such as building waste banks, recycling waste into new products, and promoting waste reuse. This study examines the forms of implementation of Good Environmental Governance in waste management in Pekanbaru. In the case of Waste Bank management in Tuah Karya, based on the principles of good environmental governance, it turns out that one of the seven principles, namely access to information, has not been able to achieve the goal of realizing a Smart City in Pekanbaru. This is because many residents are still unaware of the existence of the Waste Bank, and many are reluctant to participate. These challenges make it difficult for the Waste Bank to contribute to the ideals of Smart City in Pekanbaru.
Editorial
Authors: Filipová Lucie , Šír Jan
Published: January 2025

Editorial
“In a Sea of Fire, in a Rain of Bombs.” Jewish Children in Warsaw during September 1939 Siege
Authors: Ginsberg Eyal
Published: January 2025

The German invasion of Poland on September 1, 1939, led to the rapid evacuation of the Polish government from Warsaw, with the city eventually surrendering to the Nazis on September 28. The devastating aftermath saw a quarter of Warsaw’s houses destroyed and approximately 50,000 people killed or wounded. This article focuses on the experiences of Jewish children during this tumultuous period, a subject often overlooked in historical literature. While extensive research exists on children in Warsaw, particularly during the Ghettoization period, little attention has been given to the crucial initial month marked by both land and air assaults. Drawing from diverse sources such as diaries, archival materials, and oral testimonies, this article provides a comprehensive understanding of how Jewish children navigated the challenges of the siege and their survival strategies. By synthesizing these perspectives, it offers a nuanced analysis of their experiences, shedding light on an important aspect of this historical event.
Divided Memory: Dealing with the Past in the East German Town of Eisenhüttenstadt after the Upheaval of 1989–90
Authors: Serhiienko Stanislav
Published: January 2025

This paper explores perceptions of the German Democratic Republic (GDR) in Eisenhüttenstadt, the “first socialist town of Germany,” following the collapse of the state socialist dictatorship in East Germany. Despite its being the most well-known “socialist town” in Eastern Bloc, no systematic research has been done into how the town dealt with its troubled past. By analyzing discussion and representation of the town’s past in the public space through the year 2010, this study investigates how a town like Eisenhüttenstadt, which has no pre-socialist history, dealt with its past as East Germany transitioned away from state socialism. It also examines the impact of the town’s unique past on its current identity. The author argues that Diktaturgedächtnis [the memory of dictatorship], the lack of a pre-socialist past, and the town’s rejection of radical strategies for dealing with the past have led to complex collective memories and town identity in Eisenhüttenstadt. This complexity manifests itself in the embrace of different symbolic representations of history in different parts of the town and in splits in the public and private, and internal and external, collective memories.
Beyond Conquest: Decolonizing Adventure Sports through Outdoor Counterstories
Authors: Krásná Denisa
Published: January 2025

This paper explores decolonial outdoor counterstories written by minoritized adventure athletes, focusing particularly on Indigenous voices within the sports of rock climbing, (ski) mountaineering, highlining, and, marginally, white-water kayaking. Traditional adventure narratives have long been dominated by white, masculine figures who glorify conquest, reinforcing patriarchal, colonial, and anthropocentric ideas that marginalize diverse perspectives and contribute to environmental degradation. In contrast, contemporary decolonial counterstories challenge these exclusionary notions, reclaiming outdoor spaces and redefining success not as domination, but as a deep connection with nature, community, and personal well-being. By presenting Indigenous and other marginalized perspectives, these narratives critique and subvert Western colonial ideologies, promoting a more inclusive and ecologically mindful approach to outdoor sports. This paper argues that these counterstories contribute to the creation of a collective decolonial outdoor counternarrative that could inspire pro-environmental actions among adventure athletes who experience climate anxiety. The analysis highlights how these athletes are not only reshaping the cultural landscape of outdoor sports but also advocating for a shift from competitive dominance to collaborative coexistence, thereby supporting a more equitable and sustainable interaction with the natural world.
Pengaruh Penggunaan Jobsheet terhadap Hasil Belajar Kognitif Siswa pada Materi Waterpass di Kelas X Desain Pemodelan dan Informasi Bangunan SMK Negeri 5 Semarang
Authors: Puspasari Rizqiana Agista , Tugino  , Sucipto  , Yuhanafia Nurul
Published: January 2025

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh serta efektivitas penggunaan jobsheet terhadap hasil belajar kognitif siswa pada materi waterpass. Penelitian ini menggunakan metode penelitian eksperimen semu dengan desain penelitian nonequivalent control group design. Populasi pada penelitian ini adalah seluruh siswa kelas X Desain Pemodelan dan Informasi Bangunan SMK Negeri 5 Semarang yang mengikuti mata pelajaran Teknik Pengukuran Tanah sebanyak 107 siswa. Teknik pengambilan sampel yang digunakan adalah purposive sampling dengan jumlah sampel yang diperoleh sebanyak 71 siswa. Metode pengumpulan data pada penelitian ini menggunakan pre-test dan post-test berupa soal objektif yang telah di uji validitas, reliabilitas, tingkat kesukaran dan daya pembeda soal. Berdasarkan hasil penelitian yang diperoleh, nilai rata-rata post-test kelas eksperimen sebesar 80,95 dan nilai rata-rata post-test kelas kontrol sebesar 60,56.  Dengan analisis uji independent sample t-test diperoleh thitung 7,576 > ttabel 1,667 dengan nilai signifikansi 0,000 < 0,05. Selain itu, hasil penelitian menggunakan perhitungan N-Gain pada kelas eksperimen yang menggunakan media jobsheet diperoleh persentase sebesar 51,99% yang termasuk ke dalam kategori kurang efektif dan perhitungan N-Gain pada kelas kontrol yang tidak menggunakan media jobsheet diperoleh sebesar (-6,93%) yang termasuk ke dalam kategori tidak efektif. Dengan demikian, dapat disimpulkan bahwa penggunaan jobsheet memberikan pengaruh yang signifikan terhadap peningkatan hasil belajar kognitif siswa, namun media tersebut masih tergolong kurang efektif digunakan pada pembelajaran praktik waterpass di kelas X Desain Pemodelan dan Informasi Bangunan SMK Negeri 5 Semarang.
Produktivitas Kerja Tukang dan Pekerja Memasang Pasangan Bata, Plesteran, dan Acian (Studi Kasus Proyek Pembangunan Gedung Laboratorium Terintegrasi Fakultas Teknik Universitas Diponegoro)
Authors: Hardiyanto Antonius Erlangga , Sugiyarto Bambang , Tugino
Published: January 2025

Perencanaan sangat penting untuk memahami sejauh mana volume pekerjaan yang perlu diselesaikan serta waktu yang tersedia untuk menyelesaikannya. Agar setiap tugas dapat dilaksanakan sesuai harapan, diperlukan data yang dapat membantu kontraktor dalam menentukan jumlah kelompok pekerja yang akan digunakan untuk menyelesaikan setiap item pekerjaan. Dalam proyek konstruksi, kelompok pekerja berkolaborasi untuk menyelesaikan setiap tugas. Produktivitas adalah data yang memberikan informasi mengenai kemampuan pekerja dalam menyelesaikan suatu pekerjaan. Data produktivitas ini kemudian diolah menjadi informasi mengenai jumlah kelompok pekerja yang akan direncanakan. Pekerjaan pemasangan bata ringan, plesteran, dan acian merupakan jenis pekerjaan manual. Tujuan dari penelitian ini adalah untuk mengevaluasi produktivitas kelompok pekerja dalam melakukan pemasangan bata ringan, plesteran, dan acian. Penelitian tentang produktivitas kelompok pekerja dalam penelitian ini menggunakan pendekatan eksperimen. Peneliti melakukan observasi langsung di lapangan untuk menilai produktivitas kelompok pekerja. Dalam pengumpulan data untuk penelitian ini, peneliti menggunakan metode purposive sampling. Karena bersifat eksperimen, penelitian ini tidak bersifat umum dan hanya menyajikan informasi mengenai produktivitas berdasarkan data yang diperoleh di lapangan. Sampel dalam penelitian ini terdiri dari kelompok pekerja yang terlibat dalam pekerjaan pemasangan bata ringan dan plesteran di Proyek Pembangunan Laboratorium Terintegrasi Fakultas Teknik Universitas Diponegoro. Hasil penelitian menggambarkan bahwa produktivitas kelompok pekerja dalam pekerjaan pemasangan bata ringan mencapai 15,91 m²/hari. Sementara itu, produktivitas untuk pekerjaan pemasangan plesteran oleh kelompok pekerja adalah 21,33 m²/hari. Adapun untuk pekerjaan acian, produktivitas kelompok pekerja tercatat sebesar 18,24 m²/hari.
Pengaruh Keterampilan Critical Thinking, Communication, Collaboration, and Creativity (4C) Terhadap Hasil Belajar Siswa Pada Penerapan Model Pembelajaran Project Based Learning (PjBL) Elemen Produk Kreatif Dan Kewirausahaan Di Smk Negeri 2 Kendal
Authors: Soraya Angelia Nilam , Handayani Sri , Sucipto
Published: January 2025

Tujuan dari penelitian ini adalah (1) untuk mengetahui Keterampilan Critical Thinking, Communication, Collaboration, And Creativity (4C) dengan penerapan Model Pembelajaran Project Based Learning (2) Untuk Mengetahui Bagaimana Hasil Belajar Siswa dengan penerapan Model Pembelajaran Project Based Learning (3) Untuk Mengetahui Pengaruh Keterampilan Critical Thinking, Communication, Collaboration, And Creativity (4C) Terhadap Hasil Belajar Siswa Kelas XI Pada Elemen Produk Kreatif dan Kewirausahaan. Penelitian ini merupakan penelitian survey/asosiatif dengan jenis pendekatan kuantitatif, dengan menggunakan analisis deskriptif dan uji hipotesis menggunakan analisis regresi linier sederhana dengan software SPSS 25.0. Populasi yang digunakan dalam penelitian ini berjumlah 64 responden siswa kelas XI SMK N 2 Kendal. Metode pengumpulan data menggunakan 2 metode yaitu metode lembar tes siswa dan metode observasi keterampilan 4C. Pada penelitian ini memiliki sumbangan pengaruh sebesar 89% dan memiliki persamaan regresi linier sederhana yakni Y = 36.857 + 0.552X. Hasil penelitian ini menunjukkan bahwa; (1) Keterampilan critical thinking, communication, collaboration, and creativity (4C) siswa kelas XI pada elemen PKKWU dengan penerapan model pembelajaran project based learning menghasilkan nilai yang baik; (2) Hasil belajar siswa kelas XI pada elemen PKKWU dengan menerapkan model pembelajaran project based learning sudah menghasilkan nilai yang baik; (3) Terdapat pengaruh yang positif dan signifikan antara keterampilan critical thinking, communication, collaboration, and creativity (4C) terhadap hasil belajar siswa elemen PKKWU di SMK N 2 Kendal. Dimana jika siswa mendapatkan nilai yang baik pada keterampilan 4C maka hasil belajar pada elemen produk kreatif dan kewirausahaannya baik juga.
Remote Monitoring in Heart Failure: Revolutionizing Patient Management and Outcomes
Authors: Bashir Hanad , Prasad Pooja , Clark Cali , Bhatia Ankit , Abraham William T
Published: January 2025

Heart failure (HF) is a global health issue, contributing significantly to morbidity and mortality, particularly in North America. The management of HF is complex, requiring diligent monitoring to prevent decompensation and clinical progression. While there have been improvements in treating HF, it still leads to significant negative health outcomes and heavily contributes to the use of healthcare services. Outpatient management for HF lacks consistent application of proven therapies and the early identification and management of worsening conditions. Remote monitoring (RM) offers a solution to these challenges and there has been growing attention from HF healthcare providers and medical systems. This review explores the evolution and role of RM in the ambulatory care of HF patients, particularly emphasizing the impact of RM on clinical outcomes amid the COVID-19 pandemic.
Gyógyszerrezisztens epilepsziás betegek pszichológiai vizsgálata: affektív tényezők és társas támogatás
Authors: Csabai Orsolya , Kalmár Orsolya , Tóth Enikő , Szok Délia , Tánczos Tímea
Published: January 2025

Bevezetés: Az epilepszia krónikus agyi betegség, amelynek
kezelése elsősorban antiepileptikus gyógyszerekkel történik.
Célkitűzés: Vizsgálatunk célja a gyógyszerrezisztens
epilepsziás páciensek társas támogatásának feltérképezése, illetve az affektív
tényezők, azon belül a depresszió és a szorongás vizsgálata és összehasonlítása
volt az egészséges kontrollszemélyek állapotával. Módszer:
Kutatásunkba összesen 34 vizsgálati személyt vontunk be (22 nő és 12 férfi;
életkoruk: 21–66 év [M = 43,1, SD = 14,0]). A vizsgálatban 17 személy
gyógyszerrezisztens epilepsziás páciens (13 nő és 4 férfi; életkoruk: 21–66 év
[M = 46,6, SD = 13,5]) és 17 illesztett
kontrollszemély (9 nő és 8 férfi; életkoruk: 23–59 év [M = 39,6,
SD = 14,1]) vett részt. Az alkalmazott kérdőívek: Hospital
Anxiety and Depression Scale (HADS), Caldwell-féle Társas Támogatás Skála (SDS).
Eredmények: A vizsgált mintában a depresszió és a társas
támogatás mértéke fordított összefüggést mutatott. A depresszió nagyobb mértéke
szignifikáns kapcsolatban áll a kisebb társas támogatással: nehéz élethelyzetben
(rs [15] = –0,498, p<0,003), gyakorlati támogatásban (rs [15] = –0,622,
p<0,001), illetve azzal, hogy hány emberrel áll kapcsolatban a vizsgált
személy (rs [15] = –0,513, p<0,002). A HADS-összpontszám alapján szignifikáns
különbség mutatkozott a gyógyszerrezisztens epilepsziás és a kontrollszemélyek
között (t [24,4] = 3,40, p = 0,002, d = 1,16).
Megbeszélés: A szociális közeg megtartó és segítő szerepe
alapvető jelentőségű a krónikus gyógyszerrezisztens epilepsziás betegek
ellátásában. A társas támogatás hiányában a depresszió mértéke jelentős
növekedést mutat, ami tovább rontja a páciensek életminőségét.
Következtetés: Pilotkutatásunk eredményei rávilágítanak a
probléma időszerűségére, így elősegítheti a gyógyszerrezisztens epilepsziás
betegek részletes neuropszichológiai diagnosztikáját, ezáltal növelve a terápiás
hatékonyságot. Orv Hetil. 2025; 166(1): 20–26.
Belszervi perforációk IV-es típusú Ehlers–Danlos-szindrómában szenvedő gyermekben
Authors: Nagy Csilla , Jávorszky Eszter , Antal-Kónya Violetta , Köles Tímea , Kiss Imre , Tory Kálmán , Kálmán Attila
Published: January 2025

Az Ehlers–Danlos-szindróma IV-es (vascularis) típusa autoszomális domináns módon
öröklődő kollagénszintézis-rendellenesség, melyet általában megkésve
diagnosztizálunk. A leggyakrabban artériarepedés vagy vastagbél-perforáció
okozza az első panaszt. Dolgozatunk célja a belszervi rupturák egy lehetséges
ritka okának bemutatása egy többször műtött gyermek esete kapcsán. Ötéves fiút
vizsgáltunk erős hasi fájdalom miatt. Anamnézisében krónikus obstipatio,
minimális behatásra megjelenő suffusiók és visszatérő dysuriás panaszok
szerepeltek. Diffúz nyomásérzékenységet, izomvédekezést észleltünk. A klinikum
és a képalkotó vizsgálatok alapján bélelzáródás gyanújával laparotomiát
végeztünk, melynek során a rectosigmoidealis határon 3 mm-es perforációt
találtunk. Suturát követően a gyermek gyógyult. Kiváltó okként felmerült
krónikus székrekedés okozta bélfalgyengeség, Hirschsprung-betegség, idegen test
okozta sérülés (abúzus), gyulladásos bélbetegség és kötőszöveti betegség. A
többszervi érintettség etiológiájának konzultációja során kiderült a családban
generációkon át öröklődő fokozott vascularis fragilitás, ezért
Ehlers–Danlos-szindrómát valószínűsítettünk. A genetikai vizsgálat igazolta ezt,
a COL3A1 génben egy kóroki p.Arg449Leu missense variánst
azonosítottunk. Fél évvel az első műtét után a beteg dysuriás panaszainak
kivizsgálása során húgyhólyag-diverticulum igazolódott. A cisztoszkópiát követő
negyedik napon spontán húgyhólyagruptura alakult ki. Akut műtét során a hólyag
suturája történt, a gyermek meggyógyult. Az Ehlers–Danlos-szindróma már
gyermekkorban panaszt okozhat, akár életveszélyes állapothoz vezetve. Fontos a
panaszok hátterében a genetikai rendellenesség mielőbbi felismerése és a beteg
gondozásba vétele. Nem javasolt az erőlködés, a fokozott terhelés, és relatíve
kontraindikált a kolonoszkópia és a cisztoszkópia is. Orv Hetil. 2025; 166(1):
27–32.
HPV-associated cervical intraepithelial neoplasia: treatment and rehabilitation in perimenopausal women
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Laskava T.G. , Nykoniuk T.R. ,   Bogomolets National Medical University, Kyiv, Ukraine, Kovaliuk T.V. ,   Bogomolets National Medical University, Kyiv, Ukraine,
Published: January 2025

Optimization of postoperative rehabilitation of women with recurrent of cervical intraepithelial neoplasia (CIN) II contributes to a decrease in the frequency of postoperative complications and an increase in the efficiency of cervical epithelialization.
The aim is to reduce the frequency of complications after destructive treatment of recurrent CIN in perimenopausal women.
Materials and methods. 60 HPV-positive perimenopausal women with verified recurrent CIN II were examined. After radiowave conization, vaginal suppositories with extracts of centella asiatica seeds, calendula officinalis, aloe, tea tree essential oil; hyaluronic acid were prescribed in the Group I (n=30); vaginal suppositories with methyluracil - in the Group II (n=30). The effectiveness was assessed based on complaints, clinical manifestations, degree and duration of cervical epithelialization and complications at 6 weeks and 3 months after treatment.
Results. The high level of subjective comfort feeling at the 6th after operation in the Group I was 86.7% versus 63,4% in the Group II; at the 3rd month - 100% versus 83.3%, respectively. Pain, bloody vaginal discharge, lymphorrhea during the first 1-3 days of the postoperative period and during scab rejection on the 10-15th day were observed in 3-6% of women (Group I) versus 23-26.7% (Group II). A high degree of cervical epithelialization in the Group I occurred on 33.4±1.9 days versus 44.5±3.1 days in the Group II.
Conclusions. Radiowave conization in combination with a blend of herbal extracts for local application proves the high effectiveness of rehabilitation of women with recurrent CIN II compared to traditional management tactics.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients.
No conflict of interests was declared by the authors.
Course of the first trimester and the condition of the immune system in pregnant women after application of the assisted reproductive technologies
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Beniuk V.O. , Vygivska L.M. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: January 2025

Pregnancy, which is a consequence of the assisted reproductive technologies (ART) application, takes place in specific conditions and is accompanied by numerous complications. One of the factors’ causing infertility is disorders in the immune system (IC), which lead to a pregnancy complication.
Aim - to evaluate the course of the first trimester of pregnancy and determine the state of the immune system in women with tubal-peritoneal infertility whose pregnancy occurred application of the ART.
Materials and methods. 94 women with tubo-peritoneal type of infertility, whose pregnancy occurred as a result ART application, who formed the main group and 50 pregnant women with spontaneous onset and physiological course of pregnancy, who formed the control group, were examined. In addition, determination of the immunological link of homeostasis in all women was performed.
Results. In the first trimester of pregnancy in the main group women took place changes in the T-cell IC link, which was reflected in an increase in the number of CD3+ cells and a decrease in the number of CD8+ cells, which indicated the first degree of immune disorders. Examination of the humoral link in the main group pregnant women revealed a decrease in CD22+ cells, an increase in their absolute number together with an increase in the concentration of IgM and decrease in the concentration of IgG.
Conclusions. When analyzing the immune system in pregnant women with tubo-peritoneal type of infertility, a tendency to the formation of immune disorders in both the cellular and humoral links of the immune system due to an increase in the absolute and relative number of T-lymphocytes and a decrease in B-lymphocytes, an increase in the concentration of IgM and a decrease in the concentration of IgG, was established. confirms the activation of cellular and humoral links of the immune system.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients.
No conflict of interests was declared by the authors.
Analysis of modern markers of spontaneous preterm birth
Authors:   Dnipro State Medical University, Ukraine, Petrenko E.V. , Dubossarska Yu.O. ,   Dnipro State Medical University, Ukraine
Published: January 2025

Preterm birth (PВ) is an important problem of modern obstetrics and the main cause of morbidity and mortality among newborns worldwide.
Aim - to evaluate the clinical and anamnestic status of women with spontaneous preterm birth and to determine the role of certain haematological parameters and melatonin as prognostic markers of PB, development of pregnancy and delivery complications in such patients.
Materials and methods. The main study group included 57 women whose pregnancy ended in PB at 24-36 weeks of gestation. The control group consisted of 30 patients who had term labour. We studied the obstetric, gynaecological and somatic anamnesis of patients, including the history of pregnancy, childbirth and the postpartum period, clinical and laboratory parameters, including melatonin levels.
Results. Significant differences were found in the frequency of preterm birth in the history, which was reported by 14.0% of women in the main group and none of the patients in the control group. The percentage of women in the main group with a history of 3 or more abortions (artificial and spontaneous) was 4.8 times higher than in the control group. The overall incidence of pregnancy complications in the main group was twice as high as in the control group. The activation of the inflammatory process was confirmed by significantly increased levels of leukocytes (1.3 times) and C-reactive protein (4.9 times) in the blood serum of women in the main group. A 3.5-fold decrease in melatonin in the saliva of women with PB was found compared to the control group.
Conclusions. Among the main risk factors for spontaneous PB were the presence of a history of preterm birth, 3 or more abortions and miscarriages, concomitant gynaecological pathology, as well as a complicated course of pregnancy with cases of threatened abortion in the first and second trimesters and anaemia in the second trimester. The risk of PB was directly associated with increased levels of C-reactive protein, leukocytes, neutrophil/lymphocyte ratio, mean platelet volume and platelet distribution width, and inversely with melatonin production and magnesium levels. This allows us to consider these indicators as possible markers of preterm birth prediction.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee. Informed consent was obtained from the patients.
The authors declare no conflict of interest.
Perinatal complications of membrane premature rupture depending on laboratory markers of amniotic fluid
Authors:   Kyiv Perinatal Center, Ukraine, Tymoshchuk K.V. ,   Bohomolets National Medical University, Kyiv, Ukraine, Zahorodnia O.S. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: January 2025

Premature rupture of membranes complicates up to 10% of all births, but in the case of premature pregnancy it is the cause of one third of premature births.
Aim - to investigate the influence of low glucose concentration and increased creatinine content in amniotic fluid on the course of labor in case of premature rupture of membranes for improvement of management.
Materials and methods. The course of pregnancy in 200 women with premature rupture of membranes was analyzed. The Group 1 consisted of 50 pregnant with preretm gestation and glucose content >0.5 mmol/l, the Group 2 - 50 pregnant with preterm gestation and glucose content <0.5 mmol/l, the Group 3 - 50 pregnant in term and glucose content >0.5 mmol/l and the Group 4 – 50 pregnant in term and glucose content <0.5 mmol/l. Each group, depending on the creatinine content, was divided into subgroups A and B, the subgroup A included women with creatinine <200 mmol/l, and B - >200 mmol/l. In all pregnant women, the frequency of hyperthermia before the onset of labor and during labor, fetal distress and the need for operative delivery were analyzed.
Results. Patients with low glucose levels in amniotic fluid are more likely than those with normal glucose levels to have hyperthermia before labor begins (40% vs. 6% in preterm pregnancy, 64% vs. 10% in term pregnancy). Also noteworthy is the higher frequency of hyperthermia within 12 hours - 26% vs. 4% in preterm pregnancy, 44% vs. 6% in term pregnancy. An increase in creatinine levels against the background of low glucose levels in amniotic fluid in 35.7% is accompanied by fetal distress during labor (in women with normal creatinine levels - no more than 8.3%).
Conclusions. In women with premature rupture of membranes, reduced amniotic glucose concentration increases the risk of hyperthermia before the onset of labor and during labor, as well as other criteria for chorioamnionitis in both full-term and preterm pregnancies. Pregnant women with amniotic creatinine concentration greater than 200 mmol/l and low glucose levels have a higher rate of complications, such as fetal distress and meconium staining of the fluid.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients.
The authors declare no conflict of interest.
Coagulation and hemodynamic parameters in premature and growth restricted fetuses
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Leush S.S. , Ter-Tumasova A.G. ,   Municipal non-profit enterprise Perinatal Center of Kyiv, Ukraine
Published: January 2025

Premature birth and fetal growth retardation complicate 20% of pregnancies. Intraventricular hemorrhages cause up to 35% of neonatal losses. There is no complete understanding of the mechanisms of development and ways to prevent these complications.
Aim - to compare the indicators of newborns blood coagulation and fibrinolysis with growth retardation and prematurity, taking into account their hemodynamic prenatal characteristics for differential diagnostic of hemostasis disorders.
Materials and methods. 86 newborns and their mothers were examined. The indicators of pH, fibrinogen and D-dimer in mothers and newborns at 28-34 weeks of gestation after moderate premature birth (MPB group) and with growth restriction (FGR group) and after full-term childbirth (FT) were compared. On the eve of childbirth, hemodynamics of the uterine, umbilical cord and middle cerebral arteries were measured.
Results. The fibrinogen concentration in newborns is 2.29, 2.47 and 2.15 times lower than maternal ones respectively. The ratio of fibrinogen/D-dimer in mothers of the MPB group is 1.02x103 vs 6.7×103 and 6.5×103 of other groups. The ratio of fibrinogen/D-dimer of newborns is 2.0×103; 1.9×103 and 3.5×103 respectively. That is, in the FGR group, fibrinolysis is slowed down by 75-84% compared to MPB and FT. The peak blood flow velocity is higher in the MPB group (pulsatility index 1.99±0.204) with reduced vascular resistance (resistance index 0.87±0.048). The indicators are within the normal range in the FT group (1.17±0.062 and 1.54±0.101, respectively). Vascular resistance in the FGR group is reduced - 0.64±0.062.
Conclusions. The newborns fibrinogen content is up to 2.5 times lower than the mother's, on the contrary, the D-dimer content is 1.5-2 times higher, except for growth restricted newborns. There is a decrease in the D-dimer content in fetuses with growth retardation against the background of slow blood circulation, which indicates a decrease in fibrinolysis.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients.
No conflict of interests was declared by the authors.
Evaluation of the state of glutathione antiperoxidant system of oral fluid in adolescent smoking girls
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Lisetska I.S. , Solohub V.A. ,   Ivano-Frankivsk National Medical University, Ukraine
Published: January 2025

The powerful glutathione antiperoxidant system, which is involved in three of the four lines of defence, plays a leading role in providing antioxidant protection in the human body. It is represented by reduced glutathione and enzymes of its metabolism: glutathione peroxidase, glutathione transferase and glutathione reductase.
Aim - to study the state of the glutathione antiperoxidant system of the oral fluid in adolescent smoking girls.
Materials and methods. The study of indicators of the glutathione antiperoxidant system of oral fluid in 137 adolescent girls aged 18 to 24 years was conducted. The level of reduced glutathione was determined by the method of Travina O.V. (1955). The state of the system of glutathione-dependent enzymes was assessed by the activity of glutathione peroxidase - by the method of Vlasova SN et al. (1990); glutathione transferase activity - by the method of Vlasova SN et al. (1990); glutathione reductase activity - by the methods of biochemical studies edited by M.I. Prokhorova (1982).
Results. In adolescent girls who smoke traditional cigarettes, the most pronounced decrease in reduced glutathione activity was observed, which was 2.1 times less than in non-smokers. In participants who regularly smoked electronic cigarettes (vapes), the average activity of reduced glutathione in oral fluid was 3.75±0.02 mlmol/l, and in people who regularly smoked tobacco heating devices (IQOS) - 3.67±0.02 mlmol/l, which was 1.5 times less compared to non-smokers. Changes in the functioning of glutathione-dependent enzymes in the oral fluid of the study participants were also found depending on the presence of a bad habit and type of smoking. The glutathione-dependent enzymes of the oral fluid were characterised by activation of glutathione peroxidase and significant deficiency of glutathione transferase and glutathione reductase.
Conclusions. Thus, the changes in reduced glutathione and the system of glutathione-dependent enzymes of oral fluid in adolescent girls, which occur under the influence of smoking, depend on the type of smoking and are characterised by a decrease in the activity of reduced glutathione, glutathione transferase and glutathione reductase enzymes, as well as activation of the glutathione peroxidase enzyme.
The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients.
No conflict of interests was declared by the authors.
Cervical immune changes in women with infertility and post-traumatic stress disorder in the dynamics of treatment
Authors:   Shupyk National Healthcare University of Ukraine, Kyiv, Karlova O.O. , Blali F.E. ,   Shupyk National Healthcare University of Ukraine, Kyiv
Published: January 2025

More than 48 million couples in the world suffer from infertility, which, in addition to numerous social consequences, also has a psychological impact.
Aim - to study the peculiarities of the cervical local immune status in patients with PTSD and infertility in order to improve the treatment of fertility disorders.
Materials and methods. Cervical concentrations of IL-6, IL-8, lactoferrin and secretory leukocyte proteinase inhibitor were studied, as well as their dynamics during treatment in 112 women with infertility, divided into 3 groups. The Group I - 36 women who had the criteria of post-traumatic stress disorder syndrome, which developed after the diagnosis of infertility, the Group II - 31 women with infertility that arose against the background of post-traumatic stress disorder, Group III - 45 patients with infertility without criteria for post-traumatic stress disorder. For control, 50 healthy women were examined. Groups of infertility were divided into 2 subgroups each. 18 women of subgroup IA and 15 of IIA were treated for infertility according to its cause, 18 women of subgroup IV and 16 of IIV additionally received trauma-based psychotherapy sessions.
Results. All patients with infertility showed an increased content of all studied pro-inflammatory cytokines. After 3 months, patients of subgroups IA and IIA retained an increased content of pro-inflammatory cytokines. The content of IL-8 and lactoferrin after 3 months reached normal values in subgroups IV and IIV, and SILP - only in patients of subgroup IIV.
Conclusions. In patients of all examined groups, the level of IL-6 and IL-8, SILP and lactoferrin in cervical mucus was significantly increased compared to similar values in the control group, which indicates the activation of the anti-inflammatory link of the immunoinflammatory reaction. The highest value of IL-6 and SILP is characteristic of women of group I, lactoferrin - of women of group II. The use of trauma-oriented psychotherapy in the complex treatment of patients with infertility on the background of PTSD allows achieving a more pronounced decrease in IL-8 levels in women of subgroup IA. A decrease in cervical IL-6 and SILP concentrations on the background of psychotherapy was obtained only in women of subgroup IIV, which has a beneficial effect on the implementation of reproductive function.
The study was conducted in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the local ethics committee of the participating institution. Informed consent of the patients was obtained for the study.
The authors declare the absence of a conflict of interest.
Selection of the surgical intervention in rare cases of ectopic pregnancy: clinical cases
Authors:   Kharkiv National Medical University, Ukraine, Lakhno I.V. , Korovai S.V. ,   Communal non-commercial enterprise "Kharkiv Municipal Perinatal Center" of the Kharkiv City Council, Ukraine, Sykal I.M. ,   Kharkiv National Medical University, Ukraine, Korovai S.M. ,   Communal non-commercial enterprise "Kharkiv Municipal Perinatal Center" of the Kharkiv City Council, Ukraine, Repnikova A.V. ,   Communal non-commercial enterprise "Kharkiv Municipal Perinatal Center" of the Kharkiv City Council, Ukraine, Tkachev A.E. ,   Communal non-commercial enterprise "Kharkiv Municipal Perinatal Center" of the Kharkiv City Council, Ukraine
Published: January 2025

Ectopic pregnancy is a significant problem of modern gynecology. Recently, a new variant of ectopic pregnancy with localization in the area of the surgical scar after cesarean section has appeared. The etiology of cervical pregnancy is still unknown. Both types have a high threat to a woman's life and health. There is certain treatment strategies aimed at preserving fertility. However, the urgency of the situation affects the choice of method and volume of operative treatment.
The aim of the work was to substantiate the adequacy of access and the extent of surgical intervention in patients with ectopic pregnancy according to the clinical situation.
Clinical cases. This article demonstrates 2 cases of ectopic pregnancy that required hysterectomy. In the first case, an emergency hysteroresectoscopy was performed on a patient with vaginal bleeding due to an ectopic pregnancy in the area of the cesarean scar. However, it was not possible to stop the bleeding via coagulation of the vessels due to significant thinning and hypervascularization of the niche area. Therefore, the intervention was expanded to laparoscopy, hysterectomy. The second patient with a cervical pregnancy confirmed via ultrasonography was attended in a severe status due to a hemorrhagic shock clinic. She has been performed a laparotomy and hysterectomy.
The described clinical cases demonstrate that the bleeding and hemodynamic instability of the patient affect the choice of the volume of intervention in rare cases of ectopic pregnancy.
The study was conducted in accordance with the principles of the Helsinki Declaration. Informed consent was obtained from all patients.
The authors declare no conflict of interest.
Examining the Development of the Concept of Area in Secondary School Students with a Digital Educational Game
Authors: Alkan Selçuk , Ada Tuba
Published: January 2025

The aim of this study is to examine the effect of a digital game designed within the framework of hierarchic interactionalism theory on the development of the concept of area in secondary school students. The digital game used in this study was designed after being influenced by the
preliminary concepts and skills related to the concept of area taught in traditional activities. A qualitative research method was used to examine students' conceptual development in detail. First, preclinical interviews were conducted with the students through traditional activities related
to the concept of area. These clinical interviews were evaluated according to the criteria in Battista (2003) and Outhered and Mitchelmore (2000). Ten students having low levels in the concept of area participated in the study. Students were encouraged to use the thinking aloud technique and
thus the development of cognitive strategies related to the preconceptions and skills used in the game were revealed. At the end of the game, post-clinical interviews were conducted with the students using traditional activities and the development of the students was revealed. It was found
as a result of the present study that the digital game was quite effective on conceptual development, similar to traditional activities. Design features such as being reusable, allowing mistakes and having interactive objects shows that digital play is a more effective tool than traditional
activities.
Using Conservation Properties and Graphing Technology in Teaching Geometry
Authors: Stupel Moshe , Fravert David , Jahangiri Jay M.
Published: January 2025

The 1989 good old days' quote from the "Field of Dreams" by Kevin Costner that "If you build it, he or they will come" is no longer going to be attractive, especially in the field of mathematics education. One such challenging subject in the field of mathematics education is the teaching
and learning of geometry. It is the aim of this article to provide the pre-service and in-service geometry teachers a new perspective of teaching and learning geometrical problems that can spark students' interest to engage in geometrical tasks and build a much-needed confidence that can evolve
into a meaningful progress.
Interesting Conservation Properties of Areas in the Context of Parallelogram, Accompanied by Proofs Without Words and by Using Dynamic Research
Authors: Matan Damri , Stupel Moshe
Published: January 2025

Interesting conservation properties that exist in parallelograms are well known, such as: diagonal intersection, pairs of interior triangles that overlap each other, and other properties. This article presents a dynamic study of choosing any point inside and outside the parallelogram
and connecting it with two of the vertices of the parallelogram. It is proven mathematically and by using dynamic computer technology, that a triangle is formed, whose area is always equal to half the area of the parallelogram.
Formalizando a Inclusão da Neurodiversidade na Inteligência e Defesa Nacional do Brasil
Authors: Martini Bruno , Secchi Jamille , Sousa Lívia Aparecida de Almeida
Published: January 2025

A neurodiversidade, incluindo autismo, TDAH e dislexia, oferece grandes benefícios para a inteligência e defesa do Brasil. Em vez de ser vista como deficiência, deve ser reconhecida como uma fonte de riqueza e potencial. Integrar a neurodiversidade nesses setores pode ampliar perspectivas, criar vantagens competitivas, aproveitar habilidades únicas e melhorar a análise de ameaças e oportunidades. Exemplos práticos no Brasil incluem análise de dados, desenvolvimento de IA e cibersegurança. Entretanto, desafios como estigma, preconceito, necessidade de mudança cultural e falta de infraestrutura devem ser enfrentados. Para promover a inclusão da neurodiversidade, é essencial aumentar o conhecimento, revisar métodos de contratação, implementar políticas inclusivas e criar ambientes de trabalho acolhedores. Isso é fundamental para um Brasil mais forte, inovador e competitivo.
O papel do diagnóstico sobre a percepção da autoestima em indivíduos com TEA e/ou TDAH
Authors: Zanini Junior Carlos Antonio , Mayrink Nogueira Lorena Franklin , Zappa Lodi Sofia Rosana , Fernandes Scalvi Gustavo , Fabriz Caprara Larissa Milanezi , Biazim Miriana de Araujo , Domeniconi Camila
Published: January 2025

A autoestima desempenha um papel protetor na qualidade de vida de todas as pessoas, inclusive de indivíduos neurodivergentes. Sabe-se que o diagnóstico tardio pode impactar a percepção sobre si e em sua autoestima. O presente estudo teve como objetivo comparar a percepção da autoestima antes e depois do diagnóstico e analisar a relação entre suporte social e autoestima pós diagnóstico. A pesquisa foi realizada com 289 brasileiros, maiores de 18 anos e com diagnóstico de TEA e/ou TDAH. Todos os participantes responderam um questionário a respeito de sua percepção da autoestima antes e depois do diagnóstico. Foram coletadas também respostas qualitativas a respeito da percepção dos participantes sobre a autoestima após o diagnóstico. O recrutamento foi realizado através de divulgação nas redes sociais, e perfis oficiais da UFSCar. Os participantes tinham acesso a um formulário online que continha as respostas após receberem informações detalhadas a respeito da pesquisa e consentirem em participar. Os resultados evidenciaram melhora na autoestima pós diagnóstico, houve também uma correlação positiva e fraca entre a autoestima e suporte social percebido pelo indivíduo. Este estudo contribuiu para compreender como o diagnóstico, principalmente tardio, influencia na autoestima de indivíduos neurodivergentes.
Transformação no Sistema Agroalimentar
Authors: Aguilar Giselle , Paulino Sonia
Published: January 2025

El cambio climático ha generado crecientes preocupaciones sobre la resiliencia y sostenibilidad de los sistemas agroalimentarios. En este contexto, se ha vuelto urgente buscar alternativas efectivas para enfrentar los desafíos derivados del calentamiento global y la degradación ambiental. Este estudio examina la agroecología y la agricultura regenerativa como enfoques capaces de transformar los sistemas agroalimentarios ante estos desafíos. A través de una revisión sistemática de 54 artículos en las plataformas Web of Science y Scopus, buscamos esclarecer los beneficios y desafíos de estas prácticas. Los resultados indican que ambos enfoques promueven prácticas agrícolas que ofrecen beneficios como la mejora de la calidad del suelo, la reducción de la degradación ambiental y el secuestro de carbono, además de contribuir a la mitigación de las emisiones de gases de efecto invernadero. No obstante, sus desafíos son distintos: la agroecología se centra en el intercambio horizontal de conocimientos, empoderando a los agricultores y comunidades para reducir su dependencia de insumos externos. Sin embargo, para que su potencial se realice plenamente, es esencial eliminar las barreras para la adopción de prácticas agroecológicas. Por su parte, la agricultura regenerativa, aunque promueve prácticas resilientes al clima, no cuestiona las bases de la agricultura convencional, como la monocultura y el uso de insumos derivados del petróleo, lo que puede perpetuar un sistema que emite gases de efecto invernadero y sigue siendo vulnerable al cambio climático.
Análise da produção científica para uso sustentável da cinza da casca de arroz
Authors: Silva Lilian Tiscoski da , Madeira Kristian , Agostinetto Lenita
Published: January 2025

La generación de cascarilla de arroz durante el proceso de procesamiento es obligatoria y su aplicación para la generación de energía se ha vuelto recurrente. Así, el uso de la ceniza de cascarilla de arroz cobra relevancia para la correcta eliminación de este residuo, ya que ha sido ampliamente estudiado con su uso en diversos segmentos, por ejemplo, en la creación de polímeros, materiales cerámicos, integración en el suelo y tratamiento de efluentes. Así, el objetivo fue realizar un estudio bibliométrico de la producción científica sobre el uso sustentable de la ceniza de cascarilla de arroz. Entre los resultados encontrados, se observó que China e India son los países con mayor producción científica sobre el tema, con 8% y 7% de trabajos respectivamente y por ser los mayores productores del cereal; entre los estudios, 54 están relacionados con aplicación en la industria del cemento y el concreto; y en relación a las publicaciones, la plataforma con más publicaciones es Science Direct, con el 59% de ellas; relacionado con la revista de mayor cantidad de estudios, que es Construction & Buildings Materials, donde hay relación con el tema más estudiado. Por lo tanto concluimos que el uso de la ceniza de cáscara de arroz está ampliamente estudiado en diferentes aplicaciones y existen suficientes aportes científicos para validar su aplicación y realizar estudios de viabilidad.