bluuebunny/crossref_metadata_2025 huggingface dataset:
Real Time Assessment of Smart Concrete Inspection with Piezoelectric Sensors
Authors: Quah Tan Kai Noel , Vo Tran Vy Khanh , Tay Yi Wei Daniel , Tan Ming Jen , Wong Teck Neng , Li King Ho Holden
Published: September 2023

Utilization of an Electromechanical impedance (EMI) technique with Piezoelectric (PZT) sensors has showed potential for Structural Health Monitoring (SHM). The changes in mechanical structure via flexural bending and cracking can be detected by monitoring the deviations in electrical impedance signals recorded with embedded PZT sensors. This paper has conducted a comprehensive study on the potential of an EMI technique with embedded PZT sensors with 3D Concrete Printing (3DCP) structures subjected to flexural bending test until plastic failure. The impact of different Piezoelectric housing methods and materials has been studied comprehensively through the monitoring of EMI signals. Experimental results indicate that material housing types and thickness affect the sensitivity of EMI readings but also performed as a reinforcement when a load is directly applied. The embedded PZT sensors with the EMI technique have shown strong potential to address the cost and lifecycle challenges posed by traditional construction methods as the insertion of PZT sensors seamlessly functions with 3DCP workflows. Further developmental work can be carried out to address the sensitivity of the sensor, performance as a reinforcement, and installation automation. The results proved that the coated sensors could detect fractures in 3DCP concrete with decreased sensitivity on thicker coating layers through the variance in materials and coating thickness in the paper.
An Image Unmixing and Stitching Deep Learning Algorithm for In-Screen Fingerprint Recognition Application
Authors: Chen Xiaochuan , Feng Xuan , Li Yapeng , Duan Ran , Wang Lei , Li Yangbing , Xuan Minghua , Tan Qiaofeng , Dong Xue
Published: September 2023

The market share of organic light-emitting diode (OLED) screens in consumer electronics has grown rapidly in recent years. In order to increase the screen-to-body ratio of OLED phones, under-screen or in-screen fingerprint recognition is a must-have option. Current commercial hardware schemes include adhesive, ultrasonic, and under-screen optical ones. No mature in-screen solution has been proposed. In this work, we designed and manufactured an OLED panel with an in-screen fingerprint recognition system for the first time, by integrating an active sensor array into the OLED panel. The sensor and display module share the same set of fabrication processes when manufactured. Compared with the current widely commercially available under-screen schemes, the proposed in-screen solution can achieve a much larger functional area, better flexibility, and smaller thickness, while significantly reducing module cost. A point light source scheme, implemented by lighting up a single or several adjacent OLED pixels, instead of a conventional area source scheme as in the CMOS image sensor, or a CIS-based solution, has to be adopted since the optical distance is not long enough due to the integration. We designed a pattern for the point light sources and developed an optical unmixing network model to realize the unmixing and stitching of images obtained by each point light source at the same exposure time. After training, data verification of this network model shows that this deep learning algorithm outputs a stitched image of large area and high quality, where FRR = 0.7% given FAR = 1:50 k. In despite of a poorer quality of raw images and a much more complex algorithm compared with current commercial solutions, the proposed algorithm still obtains results comparable to peer studies, proving the effectiveness of our algorithm. Thus, the time required for fingerprint capture in our in-screen scheme is greatly reduced, by which one of the main obstacles for commercial application is overcome.
A High FoM and Low Phase Noise Edge-Injection-Based Ring Oscillator in 350 nm CMOS for Sub-GHz ADPLL Applications
Authors: Yousef Khalil , Alzahmi Ahmed
Published: September 2023

This paper presents an injection locked digitally controlled ring oscillator (IL-DCRO). To reduce jitter variations, minimize oscillator spurious signals, and eliminate periodical phase error, a double edge-injection (window injection) scheme with synchronized edge directions is proposed. A combinational edge generator is utilized to substitute the sequential edge generators for injection timing requirements relaxation. By biasing devices in deep triode, digitally controlled delay cells currents are adopted for frequency tuning. This helps reducing the devices flicker (1/f) noise and minimize the DCRO overall phase noise. At 1 MHz offset of frequency, the proposed oscillator has a measured phase noise of −125.95 dBc/Hz and −115.6 dBc/Hz at oscillation frequencies of 913.4 MHz and 432.6 MHz, respectively. Fabricated in 350 nm CMOS process, with a maximum power consumption of 3.3 mW, and oscillating at 913.4 MHz, this DCRO achieves a tuned oscillator figure of merit (FoM) of −197.35 dBc/Hz. The core area of this edge-injection-based DRCO is only 0.08 mm2.
Hospital Readmission and Length-of-Stay Prediction Using an Optimized Hybrid Deep Model
Authors: Tavakolian Alireza , Rezaee Alireza , Hajati Farshid , Uddin Shahadat
Published: September 2023

Hospital readmission and length-of-stay predictions provide information on how to manage hospital bed capacity and the number of required staff, especially during pandemics. We present a hybrid deep model called the Genetic Algorithm-Optimized Convolutional Neural Network (GAOCNN), with a unique preprocessing method to predict hospital readmission and the length of stay required for patients of various conditions. GAOCNN uses one-dimensional convolutional layers to predict hospital readmission and the length of stay. The parameters of the layers are optimized via a genetic algorithm. To show the performance of the proposed model in patients with various conditions, we evaluate the model under three healthcare datasets: the Diabetes 130-US hospitals dataset, the COVID-19 dataset, and the MIMIC-III dataset. The diabetes 130-US hospitals dataset has information on both readmission and the length of stay, while the COVID-19 and MIMIC-III datasets just include information on the length of stay. Experimental results show that the proposed model’s accuracy for hospital readmission was 97.2% for diabetic patients. Furthermore, the accuracy of the length-of-stay prediction was 89%, 99.4%, and 94.1% for the diabetic, COVID-19, and ICU patients, respectively. These results confirm the superiority of the proposed model compared to existing methods. Our findings offer a platform for managing the healthcare funds and resources for patients with various diseases.
Evaluating Sand Particle Surface Smoothness Using a New Computer-Based Approach to Improve the Characterization of Macroscale Parameters
Authors: Tessari Anthony , Muszynski Mark
Published: September 2023

The analysis of sands, and the foundation systems with which they interact, are largely dependent on macroscale behavioral parameters that represent the aggregated response of several microscale characteristics. This research paper examines the influence of surface texture, or smoothness, on the behavior of sands. The challenge of estimating or measuring smoothness, due to its microscale feature domain, is addressed through an examination of six artificially graded sand specimens. These specimens are evaluated both visually and numerically to characterize their surface smoothness. The first approach described is a simple visual method that uses a smoothness scale consistent with those of roundness and sphericity. This method, which can be performed with a tool as simple as a hand lens, evaluates a group of representative particles collectively. The second approach is also a visual evaluation, but it utilizes images obtained via scanning electronic microscopy, traditional optical microscopy, and newer low-cost digital microscopes that can be rapidly connected to a smartphone or laptop. To validate these visual estimates, a novel third approach is introduced. This approach is a more objective numerical analysis measurement technique that enables rapid and economic quantification of smoothness. This technique may assist both practitioners and academics in their understanding of the macroscale response of coarse-grained soils. In addition to the visual methods, this research also conducted several laboratory index tests to observe the mechanical behavior of the specimens, considering their particle shape and surface smoothness properties. The results indicate that angular sands have greater minimum and maximum void ratios, a larger difference between the minimum and maximum void ratios, greater critical state friction angles, and greater flow rates through an orifice of fixed size. When adjusted for surface smoothness using the proposed approach, the behavior of the sands—particularly the limit void ratio results—appears to be more predictable in some cases. These results provide additional evidence of particle smoothness contributing to the strength behavior of sand, which may be particularly useful in the domains of slope stability, land reclamation, soil–structure interaction, and soil dynamics.
Computer-Aided Design/Computer-Aided Manufacturing of Customized Abutment for Rehabilitating a Malpositioned Implant Using Digital Flow: A Case Report
Authors: Lopo Barros José Henrique , Oliveira Murilo Navarro de , Cardoso Igor Oliveiros , Oliveira Guilherme José Pimentel Lopes de , Prado Célio Jesus do , Neves Flávio Domingues Das
Published: September 2023

This study presented a rehabilitation option for malpositioned implants; this involved obtaining their position and inclination through intraoral scanning, and producing a customized abutment with CAD/CAM technology. The patient in this case report presented a root fracture in tooth 21 and was subjected to extraction, implant installation, and immediate provisional prosthesis. The implant was installed with a distal inclination due to anatomical limitations. After osseointegration, an intraoral scanning transfer provided a digital model (file extension .stl), which reproduced the implant’s position and inclination. Then, the file was sent so that a customized abutment (CAD/CAM) could be manufactured, promoting the final rehabilitation of the case; this allowed for good hygiene, load distribution in the dynamic interocclusal relationship, and favorable esthetics, whereas many would otherwise recommend implant removal. The result presented lower costs, a shorter time frame, and a lower morbidity for the patient.
A Study of the Accuracy of a 3D Indoor Camera for Industrial Archaeology Applications
Authors: Shults Roman , Levin Eugene , Aukazhiyeva Zhanar , Pavelka Karel , Kulichenko Nataliia , Kalabaev Naiman , Sagyndyk Maral , Akhmetova Nagima
Published: September 2023

The paper aims to study the geometrical quality and opportunities of the state-of-the-art 3D camera Matterport Pro and examine its potential for industrial archaeology applications. The presented study consisted of two steps. In the first step, the geometrical quality of the camera-generated point cloud was investigated on the calibration test field. The geometrical quality was checked in two ways: (1) with distance comparison between reference targets and (2) with point cloud comparison. The coordinates of the reference targets were determined using a high-precision total station, while the FARO Scanner generated the reference point cloud. The study established that Matterport Pro has a scale systematic error that must be accounted for in 3D modeling and the inventory of archaeological objects. In the second step, the geometrical quality of the camera was checked for the actual archaeological object. As such an object, the historical copper-shaft Quincy Mine in Michigan State Upper Peninsula was considered. The specific subject of the study was one of the largest hoist engines in the world. The Matterport Pro camera scanned the indoor environment of the hoist engine house. The accuracy of the 3D model of the hoist engine was checked using additional linear measurements on-site. It was found that the accuracy of 1% showed that the camera specification can be improved through calibration. As an output of the second step, the accurately refined 3D model of the hoist engine’s interior was built. That model was embedded into a 3D model of the hoist engine’s house for usage in virtual tours of the Quincy Mine Museum. Finally, a virtual tour was created of the Quincy Mine house with exterior and interior models referenced to the geographical frame.
A Multi-Framework of Google Earth Engine and GEV for Spatial Analysis of Extremes in Non-Stationary Condition in Southeast Queensland, Australia
Authors: Pakdel Hadis , Paudyal Dev Raj , Chadalavada Sreeni , Alam Md Jahangir , Vazifedoust Majid
Published: September 2023

The frequency and severity of extremes, including extreme precipitation events, extreme evapotranspiration and extreme water storage deficit events, are changing. Thus, the necessity for developing a framework that estimates non-stationary conditions is urgent. The aim of this paper is to develop a framework using the geeSEBAL platform, Generalised Extreme Value (GEV) models and spatiotemporal analysis techniques that incorporate the physical system in terms of cause and effect. Firstly, the geeSEBAL platform has enabled the estimation of actual evapotranspiration (ETa) with an unprecedented level of spatial-temporal resolution. Following this, the Non-stationary Extreme Value Analysis (NEVA) approach employs the Bayesian method using a Differential Evolution Markov Chain technique to calculate the frequency and magnitude of extreme values across the parameter space. Station and global climate datasets have been used to analyse the spatial and temporal variation of rainfall, reference evapotranspiration (ETo), ETa and water storage (WS) variables in the Lockyer Valley located in Southeast Queensland (SEQ), Australia. Frequency analysis of rainfall, ETa, and water storage deficit for 14 stations were performed using a GEV distribution under stationary and non-stationary assumptions. Comparing the ETa, ETo and ERA5 rainfall with station data showed reasonable agreement as follows: Pearson correlation of 0.59–0.75 for ETa, RMSE of 45.23–58.56 mm for ETa, Pearson correlation of 0.96–0.97 for ETo, RMSE of 73.13–87.73 mm for ETo and Pearson correlation of 0.87–0.92 for rainfall and RMSE of 37.53–57.10 mm for rainfall. The lower and upper uncertainty bounds between stationary and non-stationary conditions for rainfall station data of Gatton varied from 550.98 mm (stationary) to 624.97 mm (non-stationary), and for ERA5 rainfall datasets, 441.30 mm (stationary) to 450.77 mm (non-stationary). The results demonstrate that global climate datasets underestimate the difference between stationary and non-stationary conditions by 9.47 mm compared to results of 73.99 mm derived from station data. Similarly, the results demonstrate less variation between stationary and non-stationary conditions in water storage, followed by a sharp variation in rainfall and moderate variation in evapotranspiration. The findings of this study indicate that neglecting the non-stationary condition in some hydrometeorological variables can lead to underestimating their amounts. This framework can be applied to any geographical area for estimating extreme conditions, providing valuable insights for infrastructure planning and design, risk assessment and disaster management.
Editorial: Special Issue on “The Role of Exosomes in Cancer Diagnosis and Therapy”
Authors: Ludwig Nils , Reichert Torsten E.
Published: September 2023

As a result of extensive research in recent years, small extracellular vesicles (sEVs), also known as exosomes, are now considered major contributors to intercellular communication in health and disease [...]
The Cation/Calcium Channel of Sperm (CatSper): A Common Role Played Despite Inter-Species Variation?
Authors: Vicente-Carrillo Alejandro , Álvarez-Rodríguez Manuel , Rodriguez-Martinez Heriberto
Published: September 2023

The main cation/calcium channel of spermatozoa (CatSper), first identified in 2001, has been thoroughly studied to elucidate its composition and function, while its distribution among species and sperm sources is yet incomplete. CatSper is composed of several subunits that build a pore-forming calcium channel, mainly activated in vivo in ejaculated sperm cells by intracellular alkalinization and progesterone, as suggested by the in vitro examinations. The CatSper channel relevance is dual: to maintain sperm homeostasis (alongside the plethora of membrane channels present) as well as being involved in pre-fertilization events, such as sperm capacitation, hyperactivation of sperm motility and the acrosome reaction, with remarkable species differences. Interestingly, the observed variations in CatSper localization in the plasma membrane seem to depend on the source of the sperm cells explored (i.e., epididymal or ejaculated, immature or mature, processed or not), the method used for examination and, particularly, on the specificity of the antibodies employed. In addition, despite multiple findings showing the relevance of CatSper in fertilization, few studies have studied CatSper as a biomarker to fine-tune diagnosis of sub-fertility in livestock or even consider its potential to control fertilization in plague animals, a more ethically defensible strategy than implicating CatSper to pharmacologically modify male-related fertility control in humans, pets or wild animals. This review describes inter- and intra-species differences in the localization, structure and function of the CatSper channel, calling for caution when considering its potential manipulation for fertility control or improvement.
Effect of Short-Term High-Temperature Stimuli on the Functional Response of Trichopria drosophilae (Matsumura)
Authors: Chen Qiang , Zhang Jinlong , Tian Ye , Chen Guohua , Zhang Xiaoming
Published: September 2023

Researchers have previously investigated the role of Trichopria drosophilae as a pupal parasitoid in the biological control of Drosophila suzukii in China. Here, we investigated the ability of T. drosophilae to parasitize D. suzukii pupae at different temperatures. To do this, we evaluated the functional response of T. drosophilae to D. suzukii pupae at different temperatures and investigated the specific effects of density on parasitism. The results show that the parasitic functional response of T. drosophilae under different high-temperature stimuli is Holling type II. After processing at 29 °C, the instantaneous search rate was 1.1611; the theoretical maximum parasitic value was 20.88 at 31 °C. The parasitic efficiency decreased with increasing stimulation temperature, as the host pupa density increased from 5 to 25, and the strongest search effect occurred at 0.87 at 27 °C. The searching effect of T. drosophilae at each temperature fell gradually with an increase in prey density from 5 to 25. At 31 °C, the theoretical parasitic maximum of T. drosophilae reached a maximum of 20.88 pupae. At this temperature, when a pair of T. drosophilae was placed in a pupa density of 50, its actual total number of parasites was 18.60.
‘Candidatus Phytoplasma ziziphi’ Changes the Metabolite Composition of Jujube Tree Leaves and Affects the Feeding Behavior of Its Insect Vector Hishimonus hamatus Kuoh
Authors: Liu Rui-Chang , Li Bo-Liao , Chen Xiu-Lin , Liu Jing-Jing , Luo Kun , Li Guang-Wei
Published: September 2023

Hishimonus hamatus Kuoh is a leafhopper species native to China that feeds on Chinese jujube leaves. This leafhopper species has been verified to transmit jujube witches’ broom (JWB) disease, caused by phytoplasma, a fatal plant pathogen, which belongs to the phytoplasma subgroup 16SrV-B. The transmission of JWB phytoplasma largely relies on the feeding behavior of piercing–sucking leafhoppers. However, the specific mechanisms behind how and why the infection of JWB influences the feeding behavior of these leafhoppers are not fully understood. To address this, a study was conducted to compare the feeding patterns of H. hamatus when feeding JWB-infested jujube leaves to healthy leaves using the electrical penetration graph (EPG) technique. Then, a widely targeted metabolome analysis was performed to identify differences in the metabolite composition of JWB-infected jujube leaves and that of healthy jujube leaves. The results of EPG analyses revealed that when feeding on JWB-infected jujube leaves, H. hamatus exhibited an increased frequency of phloem ingestion and spent longer in the phloem feeding phase compared to when feeding on healthy leaves. In addition, the results of metabolomic analyses showed that JWB-infected leaves accumulated higher levels of small-molecular carbohydrates, free amino acids, and free fatty acids, as well as lower levels of lignans, coumarins and triterpenoids compared to healthy leaves. The above results indicated that the H. hamatus preferentially fed on the phloem of infected leaves, which seems to be linked to the transmission of the JWB phytoplasma. The results of metabolomic analyses partially imply that the chemical compounds might play a role in making the infected leaves more attractive to H. hamatus for feeding.
Lessons from the COVID-19 Pandemic
Authors: Giani Marco , Pozzi Matteo , Rona Roberto
Published: September 2023

The COVID-19 pandemic was an unprecedented global crisis that significantly impacted around the world [...]
The Heart and Seizures: Friends or Enemies?
Authors: Pasini Elena , Michelucci Roberto
Published: September 2023

The heart and seizures are closely linked by an indissoluble relationship that finds its basis in the cerebral limbic circuit whose mechanisms remain largely obscure. The differential diagnosis between seizures and syncopes has always been a cornerstone of the collaboration between cardiologists and neurologists and is renewed as a field of great interest for multidisciplinary collaboration in the era of the diffusion of prolonged telemonitoring units. The occurrence of ictal or post-ictal arrhythmias is currently a cause of great scientific debate with respect to the role and risks that these complications can generate (including sudden unexpected death in epilepsy). Furthermore, the study of epileptic seizures and the arrhythmological complications they cause (during and after seizures) also allows us to unravel the mechanisms that link them. Finally, intercritical arrhythmias may represent great potential in terms of the prevention of cardiological risk in epileptic patients as well as in the possible prediction of the seizures themselves. In this paper, we review the pertaining literature on this subject and propose a scheme of classification of the cases of arrhythmia temporally connected to seizures.
First-in-Human Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: Rationale and Design of the DEBuT-LRP Study
Authors: van Veelen Anna , Küçük I. Tarik , Fuentes Federico H. , Kahsay Yirga , Garcia-Garcia Hector M. , Delewi Ronak , Beijk Marcel A. M. , den Hartog Alexander W. , Grundeken Maik J. , Vis M. Marije , Henriques José P. S. , Claessen Bimmer E. P. M.
Published: September 2023

Patients with non-obstructive lipid-rich plaques (LRPs) on combined intravascular ultrasound (IVUS) and near-infrared spectroscopy (NIRS) are at high risk for future events. Local pre-emptive percutaneous treatment of LRPs with a paclitaxel-eluting drug-coated balloon (PE-DCB) may be a novel therapeutic strategy to prevent future adverse coronary events without leaving behind permanent coronary implants. In this pilot study, we aim to investigate the safety and feasibility of pre-emptive treatment with a PE-DCB of non-culprit non-obstructive LRPs by evaluating the change in maximum lipid core burden in a 4 mm segment (maxLCBImm4) after 9 months of follow up. Therefore, patients with non-ST-segment elevation acute coronary syndrome underwent 3-vessel IVUS-NIRS after treatment of the culprit lesion to identify additional non-obstructive non-culprit LRPs, which were subsequently treated with PE-DCB sized 1:1 to the lumen. We enrolled 45 patients of whom 20 patients (44%) with a non-culprit LRP were treated with PE-DCB. After 9 months, repeat coronary angiography with IVUS-NIRS will be performed. The primary endpoint at 9 months is the change in maxLCBImm4 in PE-DCB-treated LRPs. Secondary endpoints include clinical adverse events and IVUS-derived parameters such as plaque burden and luminal area. Clinical follow-up will continue until 1 year after enrollment. In conclusion, this first-in-human study will investigate the safety and feasibility of targeted pre-emptive PE-DCB treatment of LRPs to promote stabilization of vulnerable coronary plaque at risk for developing future adverse events.
Simultaneous Colonic Pressure Waves in Children and Young Adults with Gastrointestinal Motility Disorders: Artefact or Colonic Physiology?
Authors: Leibbrandt Richard , Nurko Samuel , Scott S. Mark , Dinning Phil G.
Published: September 2023

Background: Simultaneous pressure waves (SPW) spanning all recording sites in colonic manometry studies have been described as a potential biomarker of normal gas transit and extrinsic neural reflexes. In pediatric studies utilizing combined antroduodenal and colonic manometry, it was noted that most colonic SPWs appeared to also span all sensors in the gastric and small bowel regions. This suggests that a proportion of colonic SPWs may represent an artefact caused by forces extrinsic to the colon. Our aim was to characterize colonic SPWs and determine how many of these spanned most of the digestive tract. Methods: In 39 combined high-resolution antroduodenal and colonic manometry traces from 27 pediatric patients, we used our purpose-built software to identify all SPWs that spanned either (i) all recording sites in the digestive tract or (ii) those restricted to the colon. Results: A total of 14,565 SPWs were identified (364 ± 316 SPWs/study), with 14,550 (99.9%) spanning the entire antroduodenal and colonic recording sites. Only 15 SPWs (0.1% of the total) were restricted to the colon (all in one recording). Conclusions: Based on these findings, we suggest that, in pediatric studies, SPWs should not form part of any diagnostic criteria, as these events appear to be an artefact caused by factors outside the colon (abdominal strain, body motion).
Love, Like or Angry in Times of COVID-19? Analysing News Brands’ Audience Engagement on Facebook Amidst a Pandemic
Authors: Hendrickx Jonathan , Van Remoortere Annelien , Opgenhaffen Michaël
Published: September 2023

As an integral part of their online strategies and business models, news outlets diffuse their online content on social media platforms such as Facebook to increase traffic. They thereby succumb to the contingencies and constraints of third platforms infamous for their sudden changes in algorithms. In this article, we assess engagement patterns of 140,359 Facebook posts of 17 Belgian news brands between March 2020 and 2021. We map out differences in audience engagement of news outlets’ Facebook posts related and unrelated to the COVID-19 pandemic and differences between mainstream and alternative news outlets. We find that COVID-19-related posts generate more engagement and more so for mainstream media than for alternative media outlets.
Tax Shields, the Weighted Average Cost of Capital, and the Appropriate Discount Rate for a Project with a Finite Useful Life
Authors: Danielson Morris G.
Published: September 2023

The standard formulas for calculating the value of a firm’s tax shield and its weighted average cost of capital (WACC) use the assumption that the underlying cash flows are perpetuities. Yet, most projects will have a finite useful life. Because the perpetuity approach will overstate the value of a finite-life project’s tax shield, this factor will pressure the perpetuity-formula WACC to be less than the finite-life WACC. However, a large portion of the value of a perpetual tax shield can be attributed to interest payments during the next 5, 10, or 25 years, making it possible for the perpetuity-formula WACC to be greater than the finite-life WACC. Using a series of numerical examples, this paper shows that the finite-life WACC can be either higher or lower than the perpetuity-formula WACC depending on the project’s useful life, the required return on the unlevered project, the firm’s capital structure, the cost of debt, the marginal tax rate, and the debt repayment pattern (e.g., coupon bonds or amortizing loans). The analysis in this article helps managers better understand the potential biases introduced into the capital budgeting process when using the perpetuity-formula WACC to evaluate projects with finite useful lives.
Physical and Chemical Properties of Limestone Quarry Technosols Used in the Restoration of Mediterranean Habitats
Authors: Solé Pau , Ferrer Diana , Raya Irene , Pous Meri , Gonzàlez Robert , Marañón-Jiménez Sara , Alcañiz Josep Maria , Carabassa Vicenç
Published: September 2023

The lack of topsoil is frequently a limiting factor in limestone quarry restoration. This implies that new technosols for maintaining target habitats must be created using mining wastes as the main components. We designed three different technosols using different combinations of mineral materials (mining wastes, excavated soils and topsoil), organic amendment types (compost and digestate) and doses for the restoration of target habitats. Moreover, we monitored the main physicochemical indicators of the quality of the technosols. We observed not only an increase in soil organic carbon and plant nutrients related to the application of any type of organic amendment, but that the digestate mostly increased the soil resistance to erosion by improving soil aggregation even before the emergence of vegetation. Soil-water-retention capacity only improved in technosols built with organic amendments and topsoil. The combination of mining wastes, organic amendments and a superficial horizon of topsoil resulted in the most optimal technosol for the restoration of limestone quarries in the Mediterranean climate.
Spatio-Temporal Evolution of Key Areas of Territorial Ecological Restoration in Resource-Exhausted Cities: A Case Study of Jiawang District, China
Authors: Wang Fengyu , Tong Shuai , Chu Yun , Liu Tianlong , Ji Xiang
Published: September 2023

Resource-exhausted cities usually face problems of environmental degradation, landscape fragmentation, and impeded ecological mobility. By clarifying the spatial heterogeneity of ecological restoration needs, efficient and coordinated ecological protection and restoration can be carried out. This study selected Jiawang District, a typical resource-exhausted city, and constructed an ecological security evaluation framework to determine the ecological source area from the three aspects of ecosystem service importance, ecological sensitivity, and landscape stability. The resistance surface was corrected with ecological sensitivity evaluation data, and ecological corridors and ecological nodes were identified using circuit theory. Finally, it explored the spatial and temporal evolution of the key areas of territorial ecological restoration in Jiawang District. This study indicates that: (1) In 2000, 2010, and 2020, the ecological source areas were 123.59 km2, 116.18 km2, and 125.25 km2, and the corresponding numbers of ecological corridors were 53, 51, and 49. The total lengths of the ecological corridors were 129.25 km, 118.57 km, and 112.25 km, mainly distributed in the northern and central areas of the study area. (2) The study area contained 17, 13, and 19 ecological pinch points in 2000, 2010, and 2020, respectively, 16, 20, and 15 ecological obstacle points, and 8, 24, and 33 ecological fracture points, respectively. Targeted rehabilitation of these key areas can significantly improve ecological connectivity. (3) The key area of territorial ecological restoration in 2020 was composed of 125.25 km2 ecological source area, 8.77 km2 of ecological pinch point, 12.70 km2 of ecological obstacle point, and 33 ecological fracture points. According to the present situation of land use, protection strategies are put forward.
Declines in Livestock Numbers Accompany Cropping Deagrarianisation Processes in the Eastern Cape, South Africa
Authors: Shackleton Charlie , Ntshudu Monde
Published: September 2023

Deagrarianisation amongst smallholder farmers is a growing phenomenon globally, driven by a complex array of context-specific and higher-scale factors. Most research has focused on declines in arable cropping, with relatively little regard to the deagrarianisation dynamics associated with livestock ownership, yet the two are often linked through the need for draught power for ploughing. Here, we report on a survey of 293 rural households in 10 rural villages in the Eastern Cape province, South Africa, where we ascertained whether ownership of cattle, goats, sheep and pigs had changed over the previous 15 years and what were the underlying reasons for any changes at both village- and household-scale. The majority felt that there had been a decline in the number of households keeping livestock and the number of animals in the village. Additionally, a clear majority of owners for each type of livestock stated that their households currently have fewer animals than 15 years ago. The main reasons for declines were that their animals had died due to drought or disease, theft, or they had sold them because of financial needs. There was a positive association between the keeping of cattle and field cultivation. Despite these general declines, two-thirds of households currently without livestock wished that they had some, primarily for use in cultural ceremonies/rituals or for income. This study shows the deagrarianisation processes in the region also apply to the livestock sector despite the significance of livestock in the local Xhosa culture. This study highlights the multifaceted nature of deagrarianisation in communal tenure systems.
A Long-Term and Comprehensive Assessment of the Ecological Costs Arising from Urban Agglomeration Expansion in the Middle Reaches of the Yellow River Basin
Authors: Ren Xiaoyan , Yang Yuhao , Wang Zongming
Published: September 2023

The Yellow River Basin (YRB) stands as one of China’s most significant river basins, and the maintenance of its ecological functionality is of paramount importance for national well-being. The Guanzhong Plain Urban Agglomeration (GPUA), situated in the middle reaches of the YRB, represents the central hub of human activities. The rapid expansion of cities within this region poses formidable challenges to the ecological security framework of the highly sensitive middle reaches of the YRB. In this study, the dynamic equivalent coefficient method was employed to evaluate the changes in Ecological Service Values (ESVs) within the GPUA from 1990 to 2020, as well as the ecological costs incurred due to urban expansion. The results indicate the following: (1) Over the past three decades, the land-use pattern within the GPUA has undergone significant transformations. The area designated for urban development has expanded by a factor of 1.16 compared to its original extent, while the areas encompassing forests, shrubs, agricultural land, grassland, wetland, and bare land have experienced continuous reductions. (2) The ESV of the study area displays a declining trend initially, followed by a subsequent increase over the 30-year period. Forests play a predominant role in contributing to the ESV of the GPUA, with regulating services and supporting services standing out as the primary ecosystem functions. (3) The expansion of the GPUA between 1990 and 2020 has resulted in a net loss of 3772.10 km2 of ecological land. The ecological costs associated with urban expansion soar to an astonishing CNY 2.54 billion, with the highest costs attributed to the loss of hydrological regulation and soil conservation services; this issue demands significant attention. The outcomes of this research contribute to a better comprehension of the ecological costs and benefits that accompany the development of urban agglomerations in the middle reaches of the YRB. Furthermore, they provide invaluable insights for decision makers seeking to implement more effective strategies for sustainable land-use management.
The Problems of Dimension Four, and Some Ramifications
Authors: Poénaru Valentin
Published: September 2023

In this short note, I present a very quick review of the peculiarities of dimension four in geometric topology. I consider, in particular, the role of geometric simple connectivity (which means handle decomposition without handles of index one) for both closed manifolds and open manifolds and for finitely presented groups, together with some of recent developments in geometric group theory.
Accuracy of Personalized Computed Tomographic 3D Templating for Acetabular Cup Placement in Revision Arthroplasty
Authors: Winter Philipp , Fritsch Ekkehard , Tschernig Thomas , Goebel Lars , Wolf Milan , Müller Manuel , Weise Julius J. , Orth Patrick , Landgraeber Stefan
Published: September 2023

Background: Revision hip arthroplasty presents a surgical challenge, necessitating meticulous preoperative planning to avert complications like periprosthetic fractures and aseptic loosening. Historically, assessment of the accuracy of three-dimensional (3D) versus two-dimensional (2D) templating has focused exclusively on primary hip arthroplasty. Materials and Methods: In this retrospective study, we examined the accuracy of 3D templating for acetabular revision cups in 30 patients who underwent revision hip arthroplasty. Utilizing computed tomography scans of the patients’ pelvis and 3D templates of the implants (Aesculap Plasmafit, B. Braun; Aesculap Plasmafit Revision, B. Braun; Avantage Acetabular System, Zimmerbiomet, EcoFit 2M, Implantcast; Tritanium Revision, Stryker), we performed 3D templating and positioned the acetabular cup implants accordingly. To evaluate accuracy, we compared the planned sizes of the acetabular cups in 2D and 3D with the sizes implanted during surgery. Results: An analysis was performed to examine potential influences on templating accuracy, specifically considering factors such as gender and body mass index (BMI). Significant statistical differences (p < 0.001) in the accuracy of size prediction were observed between 3D and 2D templating. Personalized 3D templating exhibited an accuracy rate of 66.7% for the correct prediction of the size of the acetabular cup, while 2D templating achieved an exact size prediction in only 26.7% of cases. There were no statistically significant differences between the 2D and 3D templating methods regarding gender or BMI. Conclusion: This study demonstrates that 3D templating improves the accuracy of predicting acetabular cup sizes in revision arthroplasty when compared to 2D templating. However, it should be noted that the predicted implant size generated through 3D templating tended to overestimate the implanted implant size by an average of 1.3 sizes.
Efficacy of Wheelchair Skills Training Program in Enhancing Sitting Balance and Pulmonary Function in Chronic Tetraplegic Patients: A Randomized Controlled Study
Authors: Nam Seung-Min , Koo Dong-Kyun , Kwon Jung-Won
Published: September 2023

Background and Objectives: This study aimed to evaluate the effectiveness of a wheelchair skills training program (WSTP) in improving sitting balance and pulmonary function in patients with chronic tetraplegia resulting from cervical spinal cord injury (cSCI). Materials and Methods: Twenty-four patients were randomly divided into WSTP and control groups. The WSTP group participated in the WSTP for eight weeks, while the control group underwent conventional physical therapy for the same eight-week period. Sitting balance was evaluated using the activity-based balance level evaluation (ABLE) scale, and pulmonary function was evaluated using forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and peak expiratory flow (PEF). Results: The WSTP group showed significant improvements in both sitting balance and pulmonary function during the intervention period (p < 0.05), whereas the control group did not show any significant changes. A strong positive correlation was found between ABLE scores and all three pulmonary function parameters across all time points. Conclusions: Our results suggest that the WSTP significantly improves sitting balance and specific aspects of lung function in patients with tetraplegia.
Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment
Authors: Bravo-Perez Carlos , Guarnera Luca , Williams Nakisha D. , Visconte Valeria
Published: September 2023

Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan anchor biosynthesis class A (PIGA) gene. Clinical manifestations of PNH are intravascular hemolysis, thrombophilia, and bone marrow failure. Treatment of PNH mainly relies on the use of complement-targeted therapy (C5 inhibitors), with the newest agents being explored against other factors involved in the complement cascade to alleviate unresolved intravascular hemolysis and extravascular hemolysis. This review summarizes the biology and current treatment strategies for PNH with the aim of reaching a general audience with an interest in hematologic disorders.
Ductile Fracture Prediction in Hole Hemming of Aluminum and Magnesium Sheets
Authors: Kasaei Mohammad Mehdi , Pereira José A. C. , Carbas Ricardo J. C. , Marques Eduardo A. S. , da Silva Lucas F. M.
Published: September 2023

The present work proposes a suitable approach for predicting ductile fracture in a new joining process by plastic deformation called hole hemming. This process creates a combined form- and force-fit joint and enables the joining of lightweight materials with varying formability without requiring heating or auxiliary elements. In this process, the joinability of materials is limited by the occurrence of fracture in the outer sheet, highlighting the crucial need to accurately predict its damage during the process design phase. In this study, five different fracture criteria, including the McClintock, Rice–Tracey, Normalized Cockroft–Latham, and Brozzo and Modified Mohr–Coulomb (MMC) criteria, are examined during the joining of a challenging combination of lightweight materials (aluminum AA6082-T4 and magnesium AZ31). These criteria are calibrated by a hybrid experimental–numerical method using three tests with distinct stress states. These criteria are then implemented into the finite element model of the hole hemming process, utilizing an appropriate user subroutine. The results show that the flange edge of the outer sheet is the most prone region to fracture during the joining process, and a criterion must be able to model the fracture behavior of the material from uniaxial tension to shear to accurately predict fracture in this area. Among the examined criteria, only the MMC criterion was capable of such modeling and accurately predicted the critical displacement of the punch in the hemming stage with a negligible error (about 1%). On the other hand, the prediction accuracy of the other criteria varied significantly depending on the calibration test, resulting in errors ranging from 8.6% to 75.5%. The error of 8.6% was achieved with the Normalized Cockroft–Latham criterion calibrated by a uniaxial tension test. Thus, based on the results, the MMC criterion is recommended for ductile fracture prediction in the hole hemming process, offering valuable insights to assist in process design.
Bronchoalveolar Lavage Fluid from Chronic Obstructive Pulmonary Disease Patients Increases Neutrophil Chemotaxis Measured by a Microfluidic Platform
Authors: Ren Jiaqi , Chen Wenfang , Zhong Zhicheng , Wang Ning , Chen Xi , Yang Hui , Li Jing , Tang Ping , Fan Yanping , Lin Francis , Bai Changqing , Wu Jiandong
Published: September 2023

Chronic obstructive pulmonary disease (COPD) is a persistent and progressive respiratory disorder characterized by expiratory airflow limitation caused by chronic inflammation. Evidence has shown that COPD is correlated with neutrophil chemotaxis towards the airways, resulting in neutrophilic airway inflammation. This study aimed to evaluate neutrophil chemotaxis in bronchoalveolar lavage fluid (BALF) from COPD patients using a high-throughput nine-unit microfluidic platform and explore the possible correlations between neutrophil migratory dynamics and COPD development. The results showed that BALF from COPD patients induced stronger neutrophil chemotaxis than the Control BALF. Our results also showed that the chemotactic migration of neutrophils isolated from the blood of COPD patients was not significantly different from neutrophils from healthy controls, and neutrophil migration in three known chemoattractants (fMLP, IL-8, and LTB4) was not affected by glucocorticoid treatment. Moreover, comparison with clinical data showed a trend of a negative relationship between neutrophil migration chemotactic index (C. I.) in COPD BALF and patient’s spirometry data, suggesting a potential correlation between neutrophil migration and the severity of COPD. The present study demonstrated the feasibility of using the microfluidic platform to assess neutrophil chemotaxis in COPD pathogenesis, and it may serve as a potential marker for COPD evaluation in the future.
Centrifugal Microfluidic Synthesis of Nickel Sesquioxide Nanoparticles
Authors: Mou Jiayou , Wang Chenxi , Zhao Hongyi , Xiong Chuwei , Ren Yong , Wang Jing , Jiang Dan , Zheng Zansheng
Published: September 2023

Nickel sesquioxide (Ni2O3) nanoparticles were synthesized using centrifugal microfluidics in the present study. The obtained nanoparticles were characterized using SEM to investigate their morphology and microstructure, and XRD was employed to analyze their purity. The nanoparticle size data were measured and analyzed using ImageJ (v1.8.0) software. The flow process and mixing procedure were monitored through computational fluid dynamics simulation. Among the synthesized Ni2O3 nanoparticles, those obtained at the rotation speed of 1000 rpm for 10 min with angular acceleration of 4.2 rad/s2 showed the best performance in terms of high purity, complete shape and microstructure, small diameter, and narrow diameter distribution. The experimental results demonstrate that the rotation speed of the microfluidic chip and reaction time contribute to a decrease in particle diameter and a narrower diameter distribution range. In contrast, an increase in acceleration of the rotation speed leads to an expanded nanoparticle size range and, thus, a wider distribution. These findings contribute to a comprehensive understanding of the effects exerted by various factors in centrifugal microfluidics and will provide new insights into nanoparticle synthesis using centrifugal microfluidic technology.
Basement Mapping Using Nonlinear Gravity Inversion with Borehole and Seismic Constraints
Authors: Lyrio Julio Cesar S. O. , Li Yaoguo
Published: September 2023

We present an integrated method for mapping the basement structures of sedimentary basins by combining surface gravity data, seismic imaging, and borehole logging information. The core of the method is a nonlinear inversion algorithm for constructing the shape and depth of the basement from surface gravity data. By using the primal-logarithmic barrier method, we impose depth constraints from the borehole information. The basement depth was imaged by seismic interpretation and incorporated into the inversion as a reference model. As a result, the gravity inversion constructs basement structures that are closest to the seismic input while simultaneously satisfying the surface gravity data and borehole information. We used this new methodology to unveil the basement morphology of the Recôncavo Basin, Brazil. Recôncavo is a syn-rift onshore mature basin that exhibits a strong correlation between oil field distribution and tectonic framework. The seismic imaging in the area is ambiguous, and our approach improved the basement definition and highlighted exploration targets in the studied area.