bluuebunny/crossref_metadata_2025 huggingface dataset:
DESENVOLVIMENTO DE ESTRATÉGIAS FARMACOTERAPÊUTICAS PARA O INFARTO AGUDO DO MIOCÁRDIO: DESAFIOS E NOVAS PERSPECTIVAS, PARTE II
Authors: Paulino Emanuel Tenório , Rodrigues Amanda Karine Ferreira Barros , Rodrigues Célio Fernando de Sousa , Ribeiro Êurica Adélia Nogueira
Published: March 2022

O Infarto agudo do miocárdio é na atualidade a doença com maior prevalência ao redor do mundo e constitui o primeiro lugar no ranking de mortes precoces por agravos cardiovasculares em todo o planeta. O complexo e multifásico tratamento farmacoterapêutico aplicado às doenças isquêmicas cardíacas, tem levado a comunidade científica a repensar novas estratégias úteis na prevenção do infarto agudo do miocárdio e síndromes coronarianas que induzem lesão miocárdica de isquemia-reperfusão. Neste sentido, a cardioproteção é um tema que incita aos pesquisadores a transpor os desafios, para uma redução significante na epidemiologia do infarto e nas mortes precoces de indivíduos. Assim, este trabalho visa revisar o desenvolvimento de novas estratégias terapêuticas para a cardioproteção, trazendo as novas perspectivas e os resultados mais promissores na prevenção do infarto agudo do miocárdio, que em breve possa estar disponível na farmacoterapia avançada das doenças cardíacas. Os resultados deste trabalho mostram que o reestabelecimento de vias parassimpáticas, modulações farmacoterapêuticas em ensaios de isquemia-reperfusão com nutraceuticos e/ou fitoquímicos e/ ou a utilização da terapia gênica com células pluripotentes ou fatores que estimulam a neogênese de cardiomiócitos constituem as principais estratégias terapêuticas úteis nas pesquisas farmacológicas translacionais. Em conclusão, novas perspectivas têm sido propostas e mostram-se favoráveis ao prognóstico da cardioproteção e mostra-se como um avanço na terapia cardiovascular moderna.
Analysis of Painted Materials and the Latest Repaint Time of Arhat Statues in Zijin Nunnery, China
Authors:   National Research Center for Conservation of Ancient Wall Paintings and Earthen Sites, Department of Conservation Research, Dunhuang Academy, Dunhuang, Gansu, 736200, PR China, Cui Qiang , Shui Biwen ,   National Research Center for Conservation of Ancient Wall Paintings and Earthen Sites, Department of Conservation Research, Dunhuang Academy, Dunhuang, Gansu, 736200, PR China, Wu Fasi ,   National Research Center for Conservation of Ancient Wall Paintings and Earthen Sites, Department of Conservation Research, Dunhuang Academy, Dunhuang, Gansu, 736200, PR China, Fu Qianli ,   Emperor Qin Shihuang’s Mausoleum Site Museum, Xi’an, Shaanxi, Jiangsu, 710600, PR China, Feng Xia ,   Suzhou Wuzhong District Zijin Nunnery Scenic Spot Management Office, Suzhou, 215107, PR China
Published: March 2022

The arhat statues of Zijin Nunnery in Suzhou are painted clay statues considered to be ancient Chinese treasures, but there has been little investigation into the materials used in their manufacture along with a general lack of systematic and scientific knowledge regarding these statues. We attempted to address this deficiency in our study described here, where the materials comprising the pigment layer of the colored statues were characterized using a variety of techniques, including X-ray fluorescence, X-ray diffraction, micro infrared spectroscopy, and micro Raman spectroscopy. A range of contemporary synthetic pigments, such as chrome yellow, emerald green, and artificial ultramarine, was discovered to be available in addition to conventional inorganic pigments such as cinnabar, minium, and azurite. Analysis of the massive statue in the main hall showed that shellac is used as a surface sealing compound on the painted clay statue and beeswax as a bonding medium for the pigment layer. Following an extensive investigation into the synthetic pigments, it was determined that the painted statues of Zijin Nunnery were painted during the most recent era of the late Qing Dynasty.
Energy Legislation and Economic Transformation: The Case of the British Industrial Revolution
Authors:   School of Law, Shandong University of Technology, Kong Xiangdi ,   The Second Council of the Ecological Law and Economic Law Research Society of Zibo Law Society, Liu Wen ,   School of Law, Shandong University of Technology, Hou Chenglong ,   School of Law, Shandong University of Technology
Published: March 2022

The industrial revolution first occurred in Britain and was inextricably linked to its energy transformation. The land tenure system, the regulations of coal property rights and their changes have strongly contributed to the realization of this transformation. Therefore, based on the historical reflection on the origin of the industrial revolution, energy legislation should establish the primacy of energy transformation, gradually improve the institutional design of new energy, break the path dependence, promote energy innovation, and finally complete the historical task of economic transformation by structuring power and market with a dualistic view.
The epic genre in the works of A. Shogentsukov
Authors: Хакуашева Мадина Андреевна , Узденова Зулейха Абдулкеримовна
Published: March 2022

В статье рассматриваются эпические произведения Али Шогенцукова, относящиеся к периоду 30-х годов: поэмы «Вчерашние дни Тембота», «Партизан Жамбот», «Юный воин». Определяется жанровая система эпических произведений, характеризируется их структура, выявляются народная фольклорная основа. Анализируются особенности идиостиля, динамика формирования социального романа, эволюция перехода от лирического к эпическому жанру.

The paper examines the epic works of Ali Shogentsukov, relating to the period of the 1930s: the poems “Yesterday's Days of Tembot”, “Partisan Zhambot”, “Young Warrior”. The authors define the genre system of epic works, characterize their structure, and identify the folk folklore basis. An analysis is made of the features of the idiostyle, the dynamics of the formation of the social novel, and the evolution of the transition from the lyrical to the epic genre
Problems of cultural identification of Circassians through the prism of fine art of Karachay-Cherkesia
Authors: Сулейманова Фатима Хазерталиевна
Published: March 2022

Рассматриваются особенности культурно-идентификационных процессов в изобразительном искусстве художников-черкесов в поликультурном пространстве Карачаево-Черкесии. Искусство современных художников-черкесов КЧР интерпретируется как показатель идей, тем, образов, духовных устремлений, характеризующих не только художественную элиту, но и все общество республики. Констатируется смена парадигмы художественного развития в республике в постсоветское время и анализируются причины этой смены, проводится сравнительный анализ изобразительного искусства черкесов в других регионах. В настоящее время в искусстве Карачаево-Черкесии наблюдается нивелирование национальной черкесской идентичности, доминирование темы природы как знака снижения социальной активности мастеров кисти, уход в сферу массового искусства и дизайна, отсутствие коллективной сплоченности, определенная творческая апатия. Материалы исследования получены в результате проведенной научной группой Северокавказского филиала Государственного музея Востока весной 2021 года экспедиции в Карачаево-Черкесскую республику в рамках выполнения работы по гранту РФФИ «Культурные диффузии черкесов России и Турции: социокультурный и искусствоведческий анализ».

The paper discusses the features of cultural and identification processes in the fine art of Circassian artists in the multicultural space of Karachay-Cherkessia. The art of modern Circassian artists of Karachay-Cherkessia is interpreted as an indicator of ideas, themes, images, spiritual aspirations that characterize not only the artistic elite, but also the entire society of the republic. A change in the paradigm of artistic development in the republic in the post-Soviet era is noted and the reasons for this change are analyzed, a comparative analysis of Circassian fine art in other regions is carried out. Currently, in the art of Karachay-Cherkessia, there is a leveling of the national Circassian identity, the dominance of the theme of nature as a sign of a decrease in the social activity of brush masters, a departure into the field of mass art and design, a lack of collective cohesion, and a certain creative apathy. The materials of the study were obtained as a result of an expedition to the Karachay-Cherkess Republic conducted by a scientific group of the North Caucasus Branch of the State Museum of the East in the spring of 2021 as part of the work on the RFFI grant "Cultural diffusion of Circassians of Russia and Turkey: socio-cultural and art-historical analysis".
On the problem of the genre composition of folk prose about Zhabagi Kazanoko
Authors: Кудаева Зинаида Жантемировна
Published: March 2022

Представленная статья может рассматриваться в качестве одного из этапов разработки и воссоздания системы жанров адыгской народной несказочной прозы, результаты которого могут быть использованы в дальнейших теоретических исследованиях, а также для составления собрания адыгского прозаического фольклора. В статье исследуется цикл нарративов, связанных с именем народного мудреца и общественно-политического деятеля Кабарды Жабаги Казаноко (предположительно 1686-1750 гг.), который представлен разнообразными по своему жанровому воплощению, тематике и проблематике произведениями фольклора. В результате проведенного исследования в казаноковском цикле впервые выявлены морально-этические и этико-правовые предания, представляющие собой особые жанровые разновидности адыгской народной исторической прозы.

This work addresses one of the complex and topical theoretical problems of modern national folklore studies - the study of one of the specific layers of the Adyghe folk prose and the determination of the differentiating genre features of a number of works included in it. The article examines a cycle of narratives associated with the name of the people's sage and public and political figure of Kabarda Zhabagi Kazanoko (presumably 1686-1750), which is represented by works of folklore that are diverse in their genre, themes and problems. The purpose of the article is to identify and study new genre forms of folk non-fairytale prose that have arisen within the framework of this cycle. The study is based on theoretical and methodological guidelines developed in the works of Russian folklorists, defining the principles of identifying a genre, motive, the relationship of various genres of folklore to reality. The use of cultural-historical and comparative-historical methods of researching the works of the Adyghe oral folk prose made it possible to identify new trends in the field of genre education, caused by socio-historical conditions, occurring in the Adyghe oral folk art. As a result of the study, for the first time, moral-ethical and ethical-legal legends were revealed in the Kazanokov cycle, which are special genre varieties of the Adyghe folk historical prose. The presented article can be considered as one of the stages of development and reconstruction of the system of genres of Adyghe folk non-fairytale prose, the results of which can be used in further theoretical research, as well as for compiling a collection of Adyghe prose folklore.
Participatory Approach in Designing Tunas Bangsa 02 PAUD School Learning Facilities
Authors: Prihatmi Tutut Nani , Ghoustanjiwani Adiputra  , Hani Zulfia Zahro
Published: March 2022

School’s learning facility is one of the crucial components in supporting optimal education to achieve the educational goals, including early childhood education (PAUD). However, Tunas Bangsa 02 PAUD School is a private school that raises its finances and does not take any school fees (free tuition). The improvements to infrastructure and teaching resources are limited and carried out independently. It is necessary to have proper and directed planning so that the development of the learning facility follows the most critical needs. This study describes the design of participatory assistance to map the learning facilities. The participants in this program were the owner of the foundation, financial donors, representatives of parents, and all teachers, accompanied by a team of experts. Of the eight participatory design processes that have been implemented in this initial study, the researchers found that the participatory approach can be applied optimally and able to provide convenience for the school to map, plan and arrange their learning facilities, and a program design of Consultation Stage that consists of 5 stages can be implemented in the following years.
Aspectos dendrológicos de espécies arbóreas da Caatinga
Authors: Medeiros Thiago da Silva , Ferreira Cheila Deisy , Freire Antonio Lucineudo de Oliveira , Arriel Eder Ferreira , Bakke Ivonete Alves
Published: March 2022

Objetivou-se descrever as características macromorfológicas detalhadas de indivíduos adultos e de estruturas reprodutivas de três espécies arbóreas da Caatinga. Foram selecionados 20 indivíduos adultos de cada espécie em um fragmento de vegetação nativa de caatinga na Fazenda Experimental Nupeárido CSTR/UFCG. As três espécies desta pesquisa (Anadenanthera colubrina (Benth.) Brenan, Cenostigma nordestinum (Tul.) Gagnon & G. P. Lewis and Mimosa tenuiflora (Willd.) Poir.), são caducifólias e pertencem à família botânica Fabaceae. A espécie A. colubrina possui fuste reto, cilíndrico, base sem saliências (reta), raízes subterrâneas, a casca morta acinzentada, com estrias e grandes acúleos, enquanto que C. nordestinum e M. tenuiflora apresentam fustes na maioria dos indivíduos ramificados, retos e/ou inclinados, sem saliências, sendo que a casca morta da primeira possui coloração cinza claro, de aspecto áspero, lenticelas e desprendimento em placas; e a casca morta da segunda espécie possui coloração variando de amarronzada a castanho escura, com textura áspera ou reticulada, e presença de inúmeros acúleos pequenos e pontiagudos, desprendendo-se em fissuras longitudinais.
Budaya Politik Emha Ainun Nadjib dalam Meretas Problematika Pluralitas Agama di Indonesia
Authors: Angkat Ismail
Published: March 2022

Indonesia is a plural country of religion, race, ethnicity and culture. Apart from being a wealth of plurality, it is also a challenge, because plurality is prone to causing conflict. Religious diversity (including local religion) also makes Indonesia has the same vulnerability. For this reason, Emha Ainun Nadjib has a holistic view of how this diversity is realized and managed. This study aims to analyze Emha Ainun Nadjib's culture in hacking religious life in Indonesia. By using a qualitative approach and the theory of plurality and politics, the author maps the thoughts of Emha Ainun Nadjib in addressing these issues. The results showed that Emha Ainun Nadjib viewed plurality as an invaluable gift from God. Based on this phenomenon, Emha Ainun Nadjib provides understanding and builds awareness of the Indonesian people in processing diversity into a strength. Emha uses a political culture approach to break the chain of conflict generated by diversity into harmony.
Pelaksanaan Pendidikan Agama Islam di Universitas Asahan dan Koherensinya dengan Surat Keputusan Direktur Jenderal Pendidikan Tinggi No. 43/Dikti/Kep/2006
Authors: Pohan Sri Hairani
Published: March 2022

This study aims to analyze the learning of Islamic Religious Education at the Faculty of Economics, Asahan University. The problems studied include objectives, materials, methods, lecturer qualifications, facilities, semester credit load and learning evaluation. The various components of the problem will be analyzed for relevance by the letter of the Director General of Higher Education No. 43/DIKTI/Kep/2006 concerning guidelines for the implementation of personality development courses. The research method used is qualitative, with the technique of guaranteeing the validity of the data carried out by diligence, triangulation and member checking. The results of the study show that at Asahan University (1) the objectives of Islamic Religious Education are generally relevant to the decree in question (2) The learning materials are broadly adapted to the letter, but there is no syllabus and lesson plans prepared by lecturers of Islamic Religious Education. . (3) the learning method used is the lecture, discussion and question and answer method. (4) The qualifications of lecturers of Religious Education, Faculty of Economics, Asahan University are not relevant to the decree (5) The facilities provided are adequate to support the success of lectures, and this is also relevant to the said decree (6) The number of credits in learning is not relevant to the letter The decision letter referred to (7) evaluation of courses refers to the Faculty regulations, which is carried out with the first three stages of quizzes, second, mid-semester and lastly the end-of-semester exam.
Arsenic as an Indicator of Black Shale Assimilation by Nickel-Bearing Mafic-Ultramafic Intrusions, Muremera-Rujungu, Burundi
Authors: Evans David M. , Songore Tharcisse , Ntungwanayo Joël
Published: March 2022

The Muremera-Rujungu Ni-Cu sulfide mineralized chonolithic bodies are part of the well-endowed East African nickel belt of mafic-ultramafic intrusions in central-east Africa, dating from 1390 ± 10 Ma. Associated with the small, pod-like to tubular mineralized mafic-ultramafic intrusions is a suite of thin but extensive mafic sills that have geochemical patterns very similar to those of the marginal rocks of the chonolithic bodies (and are therefore assumed to be cogenetic) but that are generally unmineralized. The sills intrude pyrrhotite-rich phyllites (metasiltstones) that overlie a thick package of graphitic andalusite mica schists and quartzites (carbonaceous mudstones and sandstones) that are regionally enriched in As and Sb. The studied sills vary from 1 to 12 m thick, and they are distinctly differentiated into a coarse acicular-textured upper part of broadly gabbroic to quartz gabbroic composition and a granular, melanocratic pyroxene cumulate lower part, containing trace amounts of blebby sulfide and euhedral chromite. The geochemistry of the sills is typical of crustally contaminated high-Mg basaltic magma and is notable for the depletion of all chalcophile elements relative to primitive mantle melts. The chalcophile metals can be divided into two groups showing different behaviors: Cu, Bi, and Te follow S, which is preferentially concentrated in the upper, fractionated part of the sills, whereas Ni, Pt, and Pd follow As and Sb in being concentrated in the lower, cumulate part. Comparison of Ni/Cr and Ni/Mg ratios shows that this concentration of Ni exceeds that expected from accumulation in cumulus pyroxenes or chromite. The strong correlation of Ni (and to a lesser extent Pt and Pd) with As in the sills suggests a primary control by accumulation of small amounts of Ni-S-As liquid in the basal parts of the sills. We conclude that the parental magma of the sill became saturated in an immiscible S-As liquid by passing through the As-rich carbonaceous shales below and had most of its chalcophile elements stripped out by accumulation of this liquid at lower levels in the mineralizing system. Some of this early, As-rich mineralization was then reentrained by later batches of magma and incorporated into larger, composite chonolith-hosted mineralization such as at Kabanga North in Tanzania. This finding may have relevance for the methodology of future exploration in the East African nickel belt.
PHARMACOGNOSTICAL, PRELIMINARY PHYTOCHEMICAL AND IN VITRO ANTIOXIDANT EVALUATION OF THE AERIAL PARTS OF CYPHOSTEMMA SETOSUM (ROXB.)
Authors:   Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai – 600 117, Tamil Nadu, India, K Viswanath , Varghese Binoy C. , Aanandhi M Vijey
Published: March 2022

The objective of the investigation presented here is to explore the pharmacognostical nature, phytochemical characterization and in vitro antioxidant activity of Cyphostemma setosum (Roxb.). Vitis setosa (Roxb.) synonymous to C. setosum (Roxb.), is a herbaceous plant known for its folkloric treatment of ailments and belongs to the family Vitaceae. The aerial parts of the plant were collected and the pharmacognostic studies including anatomy of the aerial parts of the pant and powder microscopy, were performed. Microscopical examination of the transverse section of the leaf identified the presence of multicellular trichomes and tetracyclic stoma in the epidermal layers of the leaf. The shade dried crude plant drug powder was tested for ash values, extractive values and loss on drying. The crude drug was extracted with 80 % ethanol and fractionated with solvents of increasing polarity. The preliminary phytochemical chemical tests were done on various extracts of the powdered dried aerial parts of C. setosum (Roxb.). The phytochemical tests revealed the presence of alkaloids, tannins, flavonoids, carbohydrates, proteins, gums and quinones. These observations will be useful in evaluation of pharmacognostical and phytochemical standards to ensure the purity and quality of this plant. The chloroform, ethyl acetate and aqueous fractions of ethanolic extract of the leaves of V. setosa (Roxb.) were tested for antioxidant activity using in vitro models like nitric oxide radical scavenging study and 1,1-diphenyl, 2-picryl hydrazyl (DPPH) free radical scavenging activity. The results revealed that the fractions tested exhibit concentration dependent antioxidant activity. The ethyl acetate fraction predominant antioxidant activity than the other two fractions exhibited, while the chloroform fraction exhibited showed a minimal or less antioxidant activity when compared with standard.
NEVIRAPINE SOLID DISPERSION: DESIGN, DEVELOPMENT AND EVALUATION
Authors:   Department of Pharmaceutics, Srinath College of Pharmacy, Waluj – 431 136, Aurangabad, Maharashtra, India, Panzade Prabhakar , Shendarkar Giridhar
Published: March 2022

The objective of the present investigation was to enhance the solubility and dissolution rate of BCS class II drug nevirapine through scalable and commercially feasible solid dispersion approach by using Soluplus® (BASF) as hydrophilic carrier. The solid dispersion produced by melting method (1:5 weight ratio) exhibited highest solubility ~ 15 folds greater than pure drug. The changes in DSC, PXRD, and SEM validated the formation of solid dispersion and transformation of drug from crystalline to amorphous form. Besides, selected solid dispersion had better flow properties and higher dissolution rate than nevirapine. Furthermore, the two dissolution profiles were different (f2 value 33). Hence, preparation of nevirapine-soluplus® solid dispersion by melting method could be an appropriate pharmaco technical strategy to enhance the solubility and dissolution rate of nevirapine and probably other BCS class II drugs.
PREPARATION AND EVALUATION OF ACTIVE FILM COATING TABLET OF TENELIGLIPTIN HYDROBROMIDE HYDRATE WITH METFORMIN HYDROCHLORIDE FIXED DOSE COMBINATION
Authors: R Kumaravelrajan , M Thirumaran , T Sangavi , V Suba ,   Department of Pharmaceutics, C. L. Baid Metha College of Pharmacy, Thorapakkam, Chennai - 600 097, Tamil Nadu, India
Published: March 2022

The aim of the present study was to formulate fixed-dose combination tablets of metformin hydrochloride and teneligliptin hydrobromide hydrate. The extended-release core tablet consisted of a seal coating over metformin and outer layer coated by teneligliptin for immediate release using perforated film coating equipment. The seal coating is necessary to prevent the contact between metformin and teneligliptin. 23 Full factorial design was planned to determine critical processing parameters like the effect of hydroxypropyl methyl cellulose and ethyl cellulose in seal coating, ratio of drug and polymer in the coating solution, and spray rate as variables with lower and higher level. Optimized (F9) batch prepared from the design space from experimental variable as seal coat ratio of 0.33, drug coat ratio of 2 with rate of spray 3 g mL-1, gave desired release pattern. The optimized formulation was subjected to in vivo kinetic studies using Wistar rats. Metformin 100 mg kg-1 was administered orally and blood was withdrawn at various time intervals to assess the kinetic parameters. The observed AUC and Cmax were found to be 260 ng*h mL-1, and 58.0 ng mL-1, respectively, and the time needed to reach Tmax was 6 h for metformin tablets.
Growth and Yield of Rice Planted in a Tidal Soil Under NPK in situ and Cow Manure Application
Authors: Budianta Dedik , Alfredo Lee Panggar Bessy Jerry , Hermawan Agus
Published: March 2022

The specific location fertilization or in situ fertilization rate is a dynamic application and management method dynamically adapted to the plant’s need according to location and season related to soil chemical properties and aims to increase farmer profit. This greenhouse experiment aimed to evaluate the NPK fertilizer dose based on in situ soil chemistry of tidal swamp compared to NPK recommendation combined with cow manure from the local farm. These pot experiments were conducted from June to October 2019 in a Greenhouse of Soil Science Department, Faculty of Agriculture, Sriwijaya University, Indralaya, Ogan Ilir of South Sumatra.  This experiment used a factorial completely randomized design with two factors and three replications. The first factor was NPK fertilizer rate consisting of two levels (200 kg ha-1 Urea, 100 kg ha-1 SP-36, and 100 kg ha-1 KCl) from recommended fertilizer, and (102 kg ha-1 Urea, 0 kg ha-1 SP-36, and 66 kg ha-1 KCl) from the in situ soil analysis. The second factor was cow manure with four levels (2, 6, 8, and 10 Mg ha-1). The result showed that recommended NPK combined with 10 Mg ha-1 cow manure was the best for rice production in tidal lowland and produced 2.5 Mg ha-1.  However, this result was not significant compared to NPK specific locations combined with the same rate of cow manure.
Biocompost and Arbuscular Mycorrhizal Fungi on Chemical Properties of Inceptisols and Root Infection in Purple Corn Plants
Authors: Yusra . , . Rosnina , Aryani Dewi Sartika
Published: March 2022

The purpose of this study was to evaluate the application of biocompost and mycorrhizae fungi on chemical properties of inceptisol soil and root infection on purple corn plants.  This research was conducted in October-December 2020 at Experimental Garden, Faculty of Agriculture, Universitas Malikussaleh in Reuleut Village, Muara Batu District, Aceh Utara, employing Randomized Block Design (RBD) Factorial with 2 factors observed.  The first factor observed was different doses of biocompost: B0 (0 ton/ha, 0 g/plot), B1 (5 tons/ha, 1500 g/plot), B2 (10 tons/ha, 3000 gr/plot) and B3 (15 tons/ha, 4500 gr/plot). The second factor was M0 (0 ton/ha, 0 gr/plot, 0 g/plant), M1 (0.25 tons/ha, 75 g/plot, 5 g/plant) dan M2 (0,5 ton/ha, 150 g/plot, 10 g/plant).  The results indicated that the application of biocompost together with mycorrhizae has increased soil pH from 5.0 to 5.5 and the application of biocompost alone has improved the organic C (1.58% to 2.98%) and the application of mycorrhizae improved the root infection by 90%. The application of 5 ton/ha biocompost and 0.5 ton/ha mycorrhizae were to be found to be the best doses to improve the chemical properties of inceptisol soil and mycorrhizal infection.Keywords: biocompost, inceptisols, purple corn, mycorrhizal fungi
Effect Carrier Materials of Bradyrhizobium sp. strain PZS_A08 on Growth of Indigofera zollingeriana
Authors: Sanjaya Wilhelmus Terang Arga , Kartika Sari Yulia , Sukmadewi Desak Ketut Tristiana , Widyastuti Rahayu , Anas Iswandi
Published: March 2022

Sustainable forage production is needed to meet animal feed needs as the livestock industry increases. The purpose of this study is to evaluate the effect of liquid and solid carrier material on the effectiveness and infectivity of Bradyrhizobium sp. strain PZS_A08 on the growth of Indigofera zollingeriana (I. zollingeriana). The two carrier materials used were zeolite (solid) and molasses (liquid). This study used two carrier materials consisting of zeolite (solid) and molasses (liquid). The five treatments given were P0 (50% NPK), P1 (50% NPK+liquid biofertilizer), P2 (50% NPK+sterile liquid biofertilizer), P3 (50% NPK+solid biofertilizer), P4 (50 % NPK+sterile solid biofertilizer), P5 (100% NPK). Observations were made on the plant's height, number of leaves, number of nodules, upperparts and root wet biomass, root and upper parts dry biomass, root length, and microbial population). The use of liquid and solid carrier materials effectively affected the effectiveness and infectivity of Bradyrhizobium sp. strain PZS_A08 on  I. zollingeriana. Inoculants Bradyrhizobium sp. strain PZS_A08 significantly increased plants' growth and reduced the use of 50% NPK fertilizer. Cold storage temperature (5ºC) effectively maintained Bradyrhizobium sp. strain PZS_A08 on liquid and solid carriers, while solid carriers showed better effectiveness at room temperature storage (30oC). Through this research, solid carriers such as zeolite are recommended as carriers for Bradyrhizobium sp. filter PZS_A08.
Assessment of Three IAARD Maize Productivity In Tobadak District, Central Mamuju, Indonesia
Authors: Sirappa Marthen Pasang , Muhtar Muhtar , Heryanto Religius , Indrayana Ketut , Husnah Nurdiah
Published: March 2022

Assessment of three IAARD maize productivity was conducted in Tobadak sub-district, Central Mamuju. The purpose of the assessment was to determine the productivity of three IAARD hybrid maize. The area of   study 3 ha, applying Integrated Crop Management (ICM) models. Varieties which assessment Nasa 29, JH 37 and JH 45, and NK 212 as comparison variety. The experiments were arranged in a randomized block design which 3 times replication. Observations were made on the growth and maize yield. Based on the results of mapping of Indonesian Center for Agricultural Land Resources Research and Development (ICALRRD), land suitability classes for maize in Central Mamuju Regency which are quite suitable (S2) and marginal (S3) are 4,308 ha and 87,889 ha respectively, while that not suitability (N) covering an area of   193,441 ha with limiting factors including nutrient retention, nutrient availability, water availability, and root media. The studied was show that IARRD hybrid maize can increase productivity. The results showed that Nasa 29, JH 37, and JH 45 respectively gave yields 12.87 Mg, 9.02 Mg, and 7.77 Mg ha-1, higher than the average maize yield achieved in West Sulawesi and Central Mamuju Regency, each 4.70 Mg ha-1and 5.19 Mg ha-1. Nasa 29 gave higher yields and was significantly different compared to NK 212 (9.65 Mg ha-1) as comparison variety, and JH 37 variety was not significantly different with NK 212, but while JH 45 variety had lower results and was significantly different with NK 212. Nasa 29 and JH 37 varieties have the opportunity to be developed in Tobadak district, Central Mamuju, West Sulawesi.
The Effect of Gene Mutations on Disease Severity Scores in Pediatric Familial Mediterranean Fever Patients
Authors: GÜNGÖRER Vildan , YORULMAZ Alaaddin , ARSLAN Şükrü 
Published: March 2022

Objectives: Familial Mediterranean Fever (FMF) is a self-limiting autoinflammatory disease. In order to better understand the prognosis of diseases, disease severity scores are used. The aim of this study is to determine the effect of genetic mutations on disease severity scores in children with FMF.

Methods: 303 patients between the ages of 0-18, who were diagnosed with FMF according to Yalçınkaya-Özen diagnostic criteria and whose gene analysis was studied, were evaluated retrospectively. Pras et al's scoring system, Mor et al's scoring system and International severity score of FMF (ISSF) scoring system were applied to all patients. Genotypes were compared according to disease severity scores.

Results: When the patients were divided into 4 groups as M694V homozygous, heterozygous, M694V/other allele combined heterozygous and other mutations, according to the score of Pras et al., the frequency of mild disease tended to be less in the M694V homozygous group. When the patients divided as homozygous M694V, heterozygous M694V, heterozygous E148Q, heterozygous M694V/M680I combined mutations, according to the score of Pras et al., mild disease was found to be less common in the homozygous M694V group. When patients were divided into homozygous and heterozygous M694V groups, the disease was more severe in the homozygous M694V group according to the three scoring systems.

Conclusions: Based on the scoring system described by Pras et al., the rate of severe disease was higher in patients with homozygous M694V allele, whereas the rate of mild disease was statistically significantly higher in the heterozygous group compared with homozygous group.
Evaluation of the effectiveness of ultrasound-guided transversus abdominis plane (TAP) block for chronic pain after lower abdominal surgery
Authors: AKKEMİK Ümit , ALİYEV Dostali , ÖZGENCİL Güngör Enver
Published: March 2022

Aim: This study aimed to evaluate the effectiveness of ultrasound-guided transversus abdominis plane (TAP) block in patients diagnosed with chronic pain after undergoing lower abdominal surgery.

Methods: Patients who were admitted to the pain medicine clinic between January 1, 2016, and January 1, 2020, and underwent TAP block with the diagnosis of chronic pain after undergoing lower abdominal surgery were retrospectively analyzed. The visual analog scale (VAS) score was measured before the procedure and at the 1-month and 3-month follow-ups.

Results: The proportion of patients with a reduction in VAS scores of >50% after TAP block application was 50% at the 1-month follow-up and 72.5% at the 3-month follow-up. The changes in the VAS score was found to be statistically significant (p < 0.05).

Conclusion: Although ultrasound-guided TAP block seems to be an effective treatment method for chronic pain after lower abdominal surgery, further studies and clinical trials investigating different types of surgeries and including a larger number of patients are warranted.
Retrospective Analysis of Childhood Poisonings
Authors: GÖKÇEOĞLU Sonay , BEYAZ Emine
Published: March 2022

Aim: The aim is to determine the extent of the types of poisoning and the factors influencing them.
Method: The study was carried out between January and July of 2019. Hospital records of 107 cases who had presented to the pediatric emergency department for poisoning were retrospectively reviewed. In the analysis, descriptive statistics and the chi-square tests from univariate analyses were used. The SPSS 20.0 package program was used to analyze the data.
Results: 49.5% of the cases were girls, and 5.6% were villagers. 51.4% of poisonings occurred in spring, 68.2% were oral, pharmacological factors caused 51.4%. Poisoning of the pharmacological type was observed 17.4% less frequently in the age group 6-12 years than in other age groups, 60.3% less frequently in those who lived in the city center than in those who lived in the district, and 75.3% less frequently in those who took the drug orally than by other means (p<0.05). Poisoning occurred in 33.6% between 12:00-17:59. When analyzed by age group, poisonings are most common in the age group 0-5 years with 62.6%. Symptoms developed after poisoning in 72.0% of cases. In cases of poisoning, supportive treatment was the most commonly applied method, with 79.4%. There was no mortality due to poisoning in any of the cases.
Results: Pharmacological poisoning was detected in the majority of the cases. The risk of pharmacological poisoning was lower in children living in rural areas and the age group 6-12 years.
Evaluation of English 'Pediatric Basic Life Support' and 'Pediatric Cardiopulmonary Resuscitation' Videos in YouTube
Authors: TOSUN Osman Mücahit , HANEDAN Bülent , ÜNDAR Hasan Nabi , BOZDOĞAN Serdal , HANEDAN Bedia , ATCI Mustafa
Published: March 2022

Pediatric Basic Life Support is the initiation of cardiopulmonary resuscitation (CPR) until advanced life support is available. The American Heart Association (AHA) 2015 guideline recommend the people to perform CPR.

YouTube is a video sharing site where internet users can learn about many topics, including health. Everyone can upload videos easily. Therefore, there is no control mechanism for the accuracy and up-to-dateness of the videos. Thus, there is a risk of spreading incorrect or inaccurate information.

After the pediatric CPR and BLS guidelines were updated in 2015, we aimed to evaluate the quality and content of the videos published in English on YouTube.

The YouTube website was searched in 15th June, 2020, using the terms “pediatric cardiac massage” and “pediatric BLS”. A total of 200 videos were evaluated.by two anesthetists in terms of instructional, content, up-to dateness and resource.

33 videos included in the study were evaluated according to Azer SA criteria. 14 videos were found to be useful and 19 of them as misleading. The average total viewing times and daily viewing numbers of useful videos were found to be higher. When evaluated in terms of content, similar results were obtained in both groups. This shows that viewers value videos more being educational than content. For this reason, we think that while editing videos, Azer criteria should be taken into account as an objective criterion and their content should be prepared according to current guidelines.
Evaluation of Overall Survival Predictions In Inoperable Pancreas Ductal Adenocarcinoma
Authors: EROL Mustafa , ÖNNER Hasan , KÜÇÜKOSMANOĞLU İlknur
Published: March 2022

Objective: In this study, we aimed to determine the independent predictive parameters of overall survival (OS) ofpatients with inoperable pancreatic ductal adenocarcinoma (PDAC) and to investigate whether these parameterscan be used as potential biomarkers to shape precision medicine practices for PDAC patients.Material and Methods: The clinical and pathological data of patients who were diagnosed with inoperablepancreatic ductal adenocarcinoma between January 2016 and December 2019 and who underwent18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in our departmentwere retrospectively analyzed. Tumor diameter, maximum standardized uptake value (SUVmax), metabolictumor volume (MTV), and total lesion glycolysis (TLG) were calculated from FDG PET/CT images. Univariate andmultivariate Cox regression analyzes were performed to investigate the variable affecting overall survival. Overallsurvival data were analyzed using the Kaplan–Meier method, using the log-rank test.Results: A total of 48 patients, 31 male and 17 female, with a mean age of 65.85 ± 1.64 were included in the study.In univariate Cox regression analyzes were performed to examine the factor affecting OS. Clinicopathologicalfactors (tumor localization, tumor diameter, stage) and FDG PET/CT parameters (SUVmax, MTV and TLG) with ap-value of < 0.2 were compared to multivariate Cox regression analysis. TLG was found to be the only independentpredictor of OS. In the Kaplan-Meier analysis, the median OS duration of the patients with a median value of TLGbelow 298.34 was 13.87 months, while the median OS duration was found to be 4.97 months in patients with a TLGvalue above this value.Conclusion: In our study, TLG value, which is an FDG PET/CT parameter that reflects both the metabolic activity andthe volume of the tumor, was found to be the only independent predictor of the OS of inoperable PDAC patients.TLG can be used as a potential biomarker for survival in patients with inoperable PDAC and may assist precisionmedicine applications.
The Efficacy Of Preemptive Pregabalİn Administration on Pre-and Postoperative Anxiety and Postoperative Analgesia in Arthroscopic Shoulder Surgery: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study
Authors: ÇİÇEKCİ Faruk , SARGIN Mehmet , YILDIRIM Ahmet , KÖREZ Muslu Kazım , GÜNAYDIN Göksun , KARA  İnci
Published: March 2022

Aim: Few studies have investigated pregabalin use as preemptive analgesia in the management of acute pain and anxiety following arthroscopic shoulder surgery. We hypothesized that the preemptive use of oral pregabalin might decrease pain and postoperative anxiety on arthroscopic shoulder surgery pain during the initial 48 hours.
Patients and methods: In this prospective, randomized, double-blind, placebo-controlled study, 65 eligible patients were randomly divided into two groups, the preemptive pregabalin 150 mg (group P) and the control group (group C). The primary outcomes were pain levels measured both rest and during active motion based on a visual analog scale (VAS). Secondary outcomes were the level of anxiety (STAI-S and STAI-T), patient satisfaction, and complications.
Results: Group P showed lower pain (p < 0.001), better opioid consumption (p < 0.001), longer time to first requirement of analgesia (p < 0.001), and lower rescue analgesic dose (p < 0.001) than the control group at postoperative 48 h follow-up. Also, group P showed less preoperative and postoperative anxiety (p < 0.001) and greater patient satisfaction (p < 0.001) than group C. The rate of postoperative adverse effects was similar between the groups (p > 0.05).
Conclusion: The preemptive use of oral pregabalin received 150 mg daily for 2 days before surgery provided postoperative analgesia in both rest and active motion, and improved preoperative and postoperative anxiety levels and greater patient satisfaction in patients undergoing arthroscopic surgery.
Capacitação multiprofissional sobre a malformação congênita da fissura labiopalatina
Authors: Izidoro Thais Sales , da Silva Jaqueline Barros , Custodio Jéssica Betoni de Almeida , Vilas-Boas Maísa Rodrigues Misael , Silva Luciana Pereira , Caldeirão Talita Domingues , Mondini Cleide Carolina da Silva Demoro , Saade-Pacheco Cássia Regina
Published: March 2022

Lábio leporino é a anomalia congênita mais comum da cabeça e pescoço. É o desenvolvimento incompleto do lábio e/ou do palato (céu da boca) visto que eles se desenvolvem separadamente, durante a oitava e a décima segunda semana. A classificação mais utilizada por profissionais é a de Spina baseada no forame incisivo do palato: Grupo I- fissuras pré-forame (lábio e lábio-gengival), Grupo II- fissuras transforame (labiopalatal), Grupo III fissuras pós- forame ( palatal ) e Grupo IV- fissuras raras da face (fissuras faciais). Esse tipo de anomalia ainda não tem as causas bem definidas, provavelmente ocorre por uma combinação de fatores ambientais e genéticos. O objetivo deste estudo foi capacitar os profissionais da saúde sobre a fissura labiopalatinas e suas implicações. Tratou-se de um estudo de revisão integrativa fissura labiopalatinas em busca ativa em banco de dados da scielo, BIREME, Pubmed, para elaboração de um curso de capacitação multiprofissional e um e-book com principais orientações sobre os cuidados ao paciente relacionadas a amamentação, distúrbios de fala, odontológicos, auditivos e as etapas de reabilitação propostas pelos diferentes centros de atendimento e como os pais lidam com esta nova situação.
O lúdico na sala de aula: uma ferramenta de ensino/aprendizagem
Authors: Patrício Sandra Horstmann
Published: March 2022

Esta pesquisa nos mostra o quanto é importante para nossos alunos o ato de brincar, peça importante incluída no lúdico, com a brincadeira, o jogo ou o brinquedo, a criança resgata a auto estima, a vontade de aprender e a aprendizagem. A criança no início da alfabetização ou em outro ano, ela tem algumas dificuldades que podem ser sanadas pelo docente, através do lúdico.Desta maneira destaquei dentre as 3 peças importantes no lúdico, o jogo, pois com ele a professora ganha um aliado e facilitador da aprendizagem, possibilitando a criança a aprender de forma prazerosa e eficiente. O  lúdico é uma necessidade na vida do ser humano em todas as idades; e não deve ser vista apenas como diversão ou momentos de prazer, mas momentos de desenvolver a criatividade, a socialização, o raciocínio lógico, a coordenação motora, os domínios cognitivos, afetivos e psicomotores.
Usi espressivi della forma-canzone nelle "original soundtrack" del fenomeno Checco Zalone: performance, visioni, immaginario e crossmedialità. Da "Angela" (2009) a "L'immunità di gregge" (2020)
Authors: Bertoloni Luca
Published: March 2022

Checco Zalone is one of the most important phenomena of Italian Cinema of the last decades. One of the constants of his cinema is the presence of the song-form, in particular of original songs (original soundtrack), used as a mean to transit from the theatre, radio and TV to the cinema: this paper constitutes a sociosemiotic, interdisciplinary and culturalist analysis of the different expressive modalities with which Zalone makes use of his songs, that become a configuration element of his own style, representing a specific cinematographic way and strengthening Zalone’s authorial role in his cinema in a complex and considerable way.
Divismo, maturità e politica sessuale negli "Hollywood film" di Anna Magnani
Authors: Carnicé Mur Margarida
Published: March 2022

In the 1950s Anna Magnani played an important role in the internationalization of European stardom, becoming the first Italian actress to win an Oscar in 1955. She was 46 years old and had reached international success at the age of 37. Related to the aesthetical concerns of Italian Neorealism, and considered a pioneer in modern representation of female psychology and desire, Magnani’s case puts into question the idea that, according to Edgar Morin, grace, beauty and youth are sine qua non conditions to become a star. Between 1955 and 1960 the actress participated in three Hollywood movies along with mentoring figures such as Tennessee Williams and producer Hal B. Wallis: The Rose Tattoo (Daniel Mann, 1955), Wild is the Wind (George Cukor, 1957) and The Fugitive Kind (Sidney Lumet, 1959). Magnani’s Hollywood films suggest a kind of tailor-made melodrama, concerned in documenting her unique performative style while Hollywood experiences a great renewal of dramatic patterns and acting models. These titles also share a common subject: a passionate mature woman in crisis who, attracted to a younger man, experiences a personal rebirth closely linked to the raise of her sexuality and desire. Through the analysis of these films and how they relate to Magnani’s stardom construction in the Italian postwar, this article investigates the role of the actress in the transit of the 1950s to the 1960s. A season of great transformations in world cinema in which Hollywood, apparently interested in documenting Magnani’s uniqueness, has probably ended up discussing some of the greatest taboos in classic movies: aging over women’s bodies, erotism between mature femininity and young masculinity, or the experience of sex and passion according to a female character who remains the subject of its own desire.
El reto mexicano de construir un capital ético
Authors:   El Colegio de Morelos, González Ibarra Juan de Dios
Published: March 2022

La carencia de un capital ético que nos permita combatir la delincuencia organizada, así como la crisis actual que de lo financiero, industrial e inmobiliario se filtra en todo el cuerpo social. Paradójicamente las crisis en el sistema financiero, inmobiliario y automotriz se corresponden con muchos artículos, ensayos y libros que constantemente se escriben sobre este tema, sin embargo, ni el capital social ni el ético relacionados con la inseguridad pública deficiente son objeto de la atención que tienen, ni se les otorga el valor que ellos tienen como prerrequisitos para poder salir de la crisis.