bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding and Use of Artificial Intelligence Among Doctors in a University Hospital in Morocco
Authors: Berrami Hind , Serhier Zineb , Jallal Manar , Bennani Othmani Mohammed
Published: October 2023

Introduction: Research and development in artificial intelligence (AI) has increased dramatically over the past decade, with all areas of life being affected and particularly the medical field. It is with this in mind that this study focused on the perceptions of AI by physicians at the University Hospital of Casablanca in Morocco. Methods: A cross-sectional study conducted among physicians at the University Hospital of Casablanca in April 2023. A questionnaire was distributed electronically by sending it to the participants’ email addresses. Results: We received 103 responses to our questionnaire from physicians. The median age of the participants was 27 years with a range of 23-44 years. Concerning the seniority in clinical practice; about 59% had an experience ranging from 1 to 5 years,58% agreed that the use of medical artificial intelligence technologies will complete clinical tasks quickly, and 51% of these respondents agreed that these applications increase clinical performance. Prevalence of physicians using AI in daily life was 48% with a CI [38–57]%. The concerns perceived by the responding physicians regarding the use of artificial intelligence in the medical field were in 63% of the cases reported about the reduction of human contact with patients. Conclusion: In our study doctors have good knowledge in terms of artificial intelligence and they are open to develop their medical competences in relation with this artificial intelligence.
A Pilot Study to Assess Hydration in Geriatric Patients by Bioimpedance
Authors: Hlubik Jan , Vyslouzilova Lenka , Studnicka Filip , Vychodil Rostislav , Lhotska Lenka
Published: October 2023

Hydration plays a very important role in old age. This is because hydration changes over the course of life and therefore geriatric patients need to have their hydration monitored. However, the general problem is that there are no completely reliable methods’ that can measure this. In this paper we performed a pilot monitoring in geriatric patients and compared directly measured electrical data with results from biochemistry. The observed correlations on our pilot sample show very promising values for (r=0.68) creatinine correlation with phase angle and (r=0.71) creatinine correlation with NI (nutritional index). It also shows that electrical readings may in the future indicate much more accurately the true status of the patient. Our research is still ongoing, and we are planning further measurements on a larger sample.
Radiomics Enhances Diagnostic and Prognostic Value of Diffusion Kurtosis Imaging in Diffuse Axonal Injury
Authors: Danilov Gleb , Afandiev Ramin , Pogosbekyan Eduard , Goraynov Sergey , Pronin Igor , Zakharova Natalia
Published: October 2023

The aim of our study was to investigate the potential of advanced radiomics in analyzing diffusion kurtosis MRI (DKI) to increase the informativeness of DKI in diffuse axonal injury (DAI). We hypothesized that DKI radiomic features could be used to detect microstructural brain injury and predict outcomes in DAI. The study enrolled 31 patients with DAI (mean age 31.48 ± 11.10 years, 8 (25.8%) female) and 12 healthy volunteers (mean age 33.67 ± 11.06 years, 4 (33.3%) female). A total of 342,300 radiomic features were calculated (2282 features per each combination of 10 parametric DKI maps with 15 ROIs). Our results showed that several radiomic features were capable of distinguishing between healthy and injured brain tissue and accurately predicting outcomes with an accuracy of over 0.9. Advanced DKI radiomic features show high diagnostic and prognostic potential in DAI and may outperform average ROI values in DKI maps.
User Drafts for the Design of an mHealth Application for Equestrians
Authors: Haase Laura , Winter Julia
Published: October 2023

A study was conducted to find out user ideas for the design and workflow of an mHealth application supporting triage of horses by equestrians. Results focus on information input elements and also include some requirements for information.
Preserving Decentralized EHR-s Integrity
Authors: Kask Marten , Klementi Toomas , Piho Gunnar , Ross Peeter
Published: October 2023

A blockchain and decentralized storage technology-based architecture is proposed to support the integrity of Electronic Health Records (EHRs).
Enhancing Healthcare Through Telehealth Ecosystems: Impacts and Prospects
Authors: Manta Ourania , Vasileiou Nikolaos , Giannakopoulou Olympia , Bromis Konstantinos , Kouris Ioannis , Haritou Maria , Matsopoulos George K. , Koutsouris Dimitrios D.
Published: October 2023

This poster presents a comprehensive assessment of the transformative potential of telehealth ecosystems, integrating Internet of Things (IoT), Internet of Medical Things (IoMT), and Artificial Intelligence (AI) technologies. The study explores their impact on healthcare delivery and markets, emphasising the need for robust cybersecurity measures and technological integration. By facilitating continuous monitoring, personalised interventions, and improved patient outcomes, the integration of advanced technologies in telehealth ecosystems has the potential to revolutionise healthcare delivery and reduce healthcare costs. However, successful implementation and maximisation of their benefits require collaborative research and adherence to ethical and regulatory standards.
Pilot of Outpatient Preoperative Evaluation Through Teleassistance
Authors: Machado Claudia Regina , Neves Mario Fritsch , Costa Yago , Lunardi Claudia
Published: October 2023

The pilot project of pre-anesthetic evaluation through telemedicine at the Pedro Ernesto University Hospital (HUPE) of the State University of Rio de Janeiro (UERJ) is a commendable initiative that aims to address the challenges faced by patients in accessing preoperative care. The objective of this study was to reduce the waiting time between the surgical recommendation and its clinical clearance for the procedure. A service flow was established to enable patients to undergo a comprehensive evaluation, including examination and complementary tests, during a single visit with a general practitioner. Based on the type of surgery and the patient’s comorbidities, the Teleconsultants Center assessed the case and provided the necessary guidance. A total of 20 patients were attended to in face-to-face sessions during morning shifts, with the participation of Internal Medicine and Anesthesiology. Subsequently, these patients’ evaluations were scheduled for teleconsultation to assess their surgical risk. There has been a significant reduction in the time between the surgical recommendation and the clearance for the procedure with a notable improvement compared to the previous protocol. These initial outcomes demonstrate the project’s potential to enhance the efficiency and effectiveness of the preoperative evaluation process through teleassistance.
Evaluation of Diacerein Efficacy on Colitis as Anti-inflammatory and Anti-oxidant and its Role in Enhancing of Colon Barrier in Mice
Authors: Almezgagi MAGED , SHOAIB TAHER MUHAMMAD , ZHANG YU , Gamah Mohammed , Gao Xiang , ZHU QINFANG , ZHANG HUAN , ZHANG WEI
Published: October 2023

Ulcerative colitis (UC) is a prevalent disorder characterized by oxidative stress and the release of pro-inflammatory cytokines that disturb the colonic mucosa. Currently, available medicines for UC remain unsatisfactory. Diacerein (DIAC) has exhibited anti-oxidant and anti-inflammatory properties in wide inflammatory disorders. However, the limited understanding of DIAC's role in bowel inflammation has necessitated the investigation of its efficacy in dextran sodium sulfate (DSS)-induced UC in Balb/c mice in this study. Fifty mice were equally divided into five groups. Except for the control, all groups were given DSS for seven days to induce the colitis model. The model was treated with 25 and 50mg/kg/day of DIAC and 00mg/kg/day of 5-aminosalicylic acid (5-ASA) for ten days. Several clinical, molecular and biochemical parameters were evaluated. Following the exposure to DSS, there was a significant upregulation in the pro-inflammatory cytokines (IL-1β, IL-6, IL-17 and TNF-α) and oxidative stress index (MDA). Meanwhile, the concentration of anti-oxidative stress indices (SOD, GPx and CAT) and the levels of IL-10, mucin-1 and 2 and tight junction proteins (TJs) ZO-1 and occludin were markedly suppressed. The colon length and body weight were reduced while DAI and myeloperoxidase (MPO) were elevated. Conversely, DIAC 50mg and 5-ASA significantly reversed the altered pro-inflammatory cytokines, oxidative stress and MPO. Moreover, they significantly restored body weight, colon length, DAI, TJs, mucin-1 and 2 and IL-10. No significant results were found with DIAC 25mg. In conclusion, DIAC exhibited therapeutic effectiveness against colitis. This research may provide hope for testing its effectiveness against UC in humans
GC-MS evaluation of the essential oils from the newly developed cultivars of Satureja montana grown in southern Ukraine
Authors: Pokajewicz Katarzyna , Shanaida Mariia , Hudz Nataliia , Svydenko Liudmyla , Yezerska Oksana , Wieczorek Piotr Pawieł , Lipok Jacek
Published: October 2023

Satureja montana L. is widely used in traditional medicine and culinary. New varieties of this species are created and grown with different purposes. The essential oil (EsO) samples were obtained from the fresh flowering shoots of four new Ukrainian cultivars of S. montana: 'Krymski smaragd', 'Lunata', '697-1', and 'N3-18'. The EsO of cultivars ''Lunata' and 'Krymski smaragd' were studied in two following harvest years (2019 and 2020). The EsO samples were analyzed using gas chromatography-mass spectrometry (GC-MS). More than 60 components were identified in the studied EsO. Carvacrol was the principal component of all the samples (58.3-87.0% (as GC-MS relative abundances). p-Cymene was the second predominant component (5.0–8.8%) in the EsO of all the cultivars collected in the 2020 year, while cultivars ''Lunata' and 'Krymski smaragd' gathered in 2019 contained it in much fewer amounts (1.7% and 0.5%, respectively). γ-Terpinene was the third main component of EsO of the most studied varieties (0.9% to 6.6%). Only cultivar 'N697-1' contained carvacrol methyl ether at a significant level (11.7%). All the tested samples met the requirements of International Standard Organization (ISO) 79284:1991(E), supposing that the qualitative composition of the S. montana EsO should comprise the following main constituents: γ-terpinene, p-cymene, linalool, terpinen-4-ol, and carvacrol. It can be concluded that we dealt with the carvacrol chemotypes of S. montana. It was also revealed that growth year influenced the EsO composition of 'Krymski smaragd' and 'Lunata' cultivars. Our results afforded to compare the EsO of the S. montana new cultivars
ANTIOXIDANT POTENTIAL OF CORNELIAN CHERRY (Cornus mas L.) FROM MONTENEGRO
Authors: Blagojevic Nada , Kandic Mara , Vukasinovic Pesic Vesna , Brasanac Vukanovic Snezana , Tadic Vanja , Bojovic Dragica
Published: October 2023

Abstract: In this work, total phenols, flavonoids, tannins, anthocyanins, the antioxidant capacity (by the DPPH and FRAP method) were determined in the juice and pomice of cornelian cherry from the area of Montenegro. Also, content of microelements and macroelements in the juice, pomice and fruit of cornelian cherry were investigated. In the studied cornelian cherry samples, the content of phenols ranged from 159.57 to 244.93 mg GAE/100 g, flavonoids from 71.74 to 165.5 mg QE/100 g, tannins from 0.33 to 0.81 %, total anthocyanins 0.057-0.310 %. HPLC analysis identified anthocyanins: delphinidin-3-O-glucoside, cyanidin-3-O-galactoside, cyanidin-3-O-glucoside, pelargonin-3-O-glucoside and its derivative. The most abundant essential microelement in the studied cornelian cherry samples was Fe (23.44-37.69 mg/kg), followed by Zn (3.14-6.25 mg/kg), Cu (1.50-1.80 mg/kg) and Mn (0.58-0.78 mg/kg). The most abundant essential macroelement in the examined samples was K (2427.8-3276.2 mg/kg), followed by Ca (361.5-475.7), Mg (95.41-146.5 mg/kg) and Na (8.347-16.59 mg/kg). Pb, Cd and Ni were not detected in the tested samples. A high degree of correlation was obtained between the content of total flavonoids and antioxidant value measured by the FRAP method (R = 0.96), as well as between the content of total anthocyanins and antioxidant activity measured by the DPPH method (R = 0.89). Of individual anthocyanins, high correlation values were shown by cyanidin-3-O-galactoside (R = 0.96), cyanidin-3-O-glucoside (R = 0.95) and pelargonin-3-O-glucoside (R = 0.94) with antioxidant activity measured by the DPPH method.
Comparison of physiological state and conditions imitating the comorbidity of type 2 diabetes with Alzheimer's disease. The impact on: proliferation, H2O2, Aβ42, S100A8, S100B levels, neuronal protrusion and neurogenesis
Authors: Kubis-Kubiak Adriana , Wiatrak Benita , Piwowar Agnieszka
Published: October 2023

Abstract
Aim: Recent studies demonstrate that individuals with T2DM more likely to develop AD. While, disturbed glucose or insulin homeostasis, are at the forefront of AD research, not much is known about extra- and intracellular interplay between different forms of Aβ and microenviromental fluctuations of glucose or insulin concentrations in neuronal cells.
Methods: We create conditions imitating the coexistence of T2DM with AD and compare the results with state where the neuropathological changes are yet not developed. We have investigated the effect of the physiological (Aβ40) and toxic amyloid form (Aβ25–35) and its co-incubation with glucose or insulin on neuronal proliferation, H2O2, Aβ42, S100B, S100A8 protein concentrations, mature neuronal protrusions and neurogenesis.
Results: Aβ40 and Aβ25-35 with hyperglycaemia provoked stronger cytotoxic effect comparing to Aβ alone, while hyperinsulinemia dampen this effect. Opposite results were obtained in H2O2 measurement. Insulin stimulated Aβ42 generation when co-incubated with both Aβ forms. Aβ40 and Aβ25-35 caused similar pattern of extracellular S100B protein influx an concomitant cytosolic efflux. Neuronal protrusions and neurogenesis were initiated by co-incubation of Aβ40 with hyperglycaemia while reduced in Aβ25-35 and hyperglycemia or insulinemia.
Significance: Our finding suggest that for understanding the biochemical origins of neuropathological amyloid β progression and potential involvement of metabolic disturbances in this process, it’s crucial to gasp preliminary interactions on cellular level. Our data can lead to hypothesis that S100B protein could be a potential modulator as well as indicator of prodromal neuropathological alterations.
Treatment with Antitumor Agents Recommended by Cancer Genome Panel for Uterine Leiomyosarcoma
Authors: Hayashi Takuma , Tamura Saya , Abiko Kaoru , Konishi Ikuo
Published: October 2023

To date, cancer genomic medicine, using cancer gene panel covered by health insurance in June 2019, has been performed for advanced malignant tumors under public medical insurance. In gynecology, the first-line treatment for uterine leiomyosarcomas, which is a mesenchymal uterine tumor, is surgery. In uterine leiomyosarcoma cases, recurrence is observed within 2 years postoperatively; however, to date, clinical trials have not shown efficacy with existing antitumor agents. Currently, two cases of advanced uterine leiomyosarcomas have been associated with increased tumor mutation burden (TMB) or pathogenic variants (PVs) in the AKT serine/threonine kinase 1 (AKT). Therefore, treatment with pembrolizumab, which is a drug covered by insurance for patients with TMB high, or treatment with kinase inhibitors for patients with PVs in AKT, was considered. Cancer genomic medicine using cancer gene panel provides a new treatment strategy for intractable malignant tumors. This study aimed to discuss the usefulness of cancer genomic medicine by cancer gene panel testing using the case of advanced and recurrence uterine leiomyosarcoma and the latest findings.
Understanding the Sustainability of Materials through a Case Study of Rebuilding a Traditional Village House Using the Carbon Footprint Approach
Authors: Sakhlecha Manish , Bajpai Samir , Ralegaonkar Rahul , Datta Rahul
Published: October 2023

Houses in villages that are traditionally built with locally available materials like wood, mud, and stones are nowadays being demolished and reconstructed. The current trend has been to adopt framed construction with reinforced cement concrete and red bricks as the main materials. This is going to have a significant environmental impact and needs to be addressed with critical observations. This study is conducted for a local village in Tripura state, India, where a new house for the economically weaker section was constructed using stabilized mud blocks and bamboo as a model house. The main objective is to investigate the environmental impact of the transformation of a traditional house constructed out of locally available materials versus masonry and concrete houses. The impact has been represented as the difference in the Carbon footprint of the two houses based on the LCA approach. It was found that the total carbon footprint of the house built with locally available bamboo and stabilized mud bricks is 9.599 tons, 11.736 tons, and 11.401 tons lower in landfilling, waste treatment, and circular economy, respectively, as compared to concrete and masonry houses, and it has the potential to reduce the impact of the production stage to be negative.
Exploring the Synergistic Approach of Dual GLP-1 Agonist with Degludec Basal Insulin for Early Type 1 Diabetes Treatment for Albumin-Insulin Producing Cells Expression
Authors: Ahmed Amr , Akl Maher M.
Published: October 2023

This manuscript explores various aspects related to the use of dual GLP-1 agonist with degludec basal insulin as a potential treatment approach for early type 1 diabetes. The background section highlights the destruction of beta cells in early type 1 diabetes and the emergence of GLP-1 agonists as a promising option for managing obesity and type 2 diabetes. The authors discuss a retrospective analysis of the efficacy of semaglutide, a GLP-1 agonist, in patients with newly diagnosed early type 1 diabetes. The results show the elimination of prandial and basal insulin, increased C-peptide levels, and improved glycemic control. However, the study's retrospective nature and lack of a control group emphasize the need for larger prospective trials. The interpretation section highlights the potential of GLP-1 agonists in protecting residual beta cells, stimulating cell proliferation, and reprogramming liver cells into insulin-producing cells. Moreover, modifying GLP-1 agonists with albumin ligands shows promise in extending their half-life and enhancing their anti-diabetic effects. The perspective section provides a comprehensive overview of the synergistic approach, considering the pharmacokinetic properties of degludec, the plasticity of adult human hepatic tissue, and the benefits of modified GLP-1 derivatives. The conclusion emphasizes the need for further research to explore the full potential of this approach in early type 1 diabetes treatment. The proposed approach offers a promising avenue for the treatment of early type 1 diabetes, integrating the autoimmune hypothesis, the proliferative effects of GLP-1, and modifications using albumin ligands. By combining these elements, we can strive towards restoring beta cell mass and function, ultimately improving the lives of individuals living with type 1 diabetes. The manuscript is planned to undergo clinical trials in 2024, registered as 'Amr Ahmed, Maher M. Akl, Semaglutide GLP1 Agonists with Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus' with CLINICALTRIALS.GOV IDENTIFIER NCT06057077.
A single hidden variable interpretation of the quantum wave function
Authors: Gentile David
Published: October 2023

An interpretation of quantum mechanics is presented in which there is one hidden variable. While this number of hidden variables is insufficient to explain Bell nonlocality, it can help solve the measurement problem. It also provides an explanation of the delayed choice quantum eraser experiment that is more intuitive than current explanations. In addition, a theory of nonlocality emerges directly from its assumptions. The key idea is that from the perspective of an outside observer, not correlated with an observed system, we treat all interactions within the system as unitary. However, from the perspective of an “observer” inside the system, we treat all new entanglements as “micro-measurements” and as a projection onto some basis of measurement. One particle can “measure” another. Thus, particles will have a defined value on one measurement basis from an inside perspective. This means that the wave function, from the outside view, will at times describe an objective uncertainty, at other times a subjective uncertainty and at yet other times a combination of both. The standard wave function describes the total uncertainty, the minimal uncertainty that is present for any observer outside of the system, while for an “observer” inside the system, only the objective part of the uncertainty remains, and this can be described by an inner wave function. The hidden variable is invisible to the outside observer.
Multiplicity of solutions for nonlocal fractional equations with nonsmooth potentials
Authors: Yuan Ziqing , Yu Lin
Published: October 2023

This paper is concerned a specific category of nonlocal fractional Laplacian problems that involve nonsmooth potentials. By utilizing an abstract critical point theorem for nonsmooth functionals and combining it with the analytical framework on fractional Sobolev spaces developed by Servadei and Valdinoci, we are able to establish the existence of at least three weak solutions for nonlocal fractional problems. Moreover, this work also generalizes and improves upon certain results presented in the existing literature.
Komunikasi Antarpribadi Mentor dan Mahasiswa dalam Meningkatkan Skill Mahasiswa melalui Program Magang ANTV
Authors: Kusumah Nur Wulan Abiyah , Hamzah Radja Erland , Lubis Adiella Yankie
Published: October 2023

Penelitian ini menggunakan metode kualitatif dengan studi fenomenologi dan pendekatan konstruktivisme sebagai teknik pengumpulan data secara wawancara mendalam dan terbuka. Teori yang digunakan dalam penelitian ini menggunakan teori komunikasi antarpribadi. Program magang memberikan berbagai kesempatan, dan tantangan kepada seluruh mahasiswa, sehingga mahasiswa mampu meningkatkan serta mengembangkan kreativitas, kepribadian, kapasitas diri, dan kemandirian untuk mencari ilmu baru melalui berbagai kenyataan dan dinamika dilapangan seperti pemecahan masalah, komunikasi, etika komunikasi,dan berkolaborasi dengan berbagai pihak eksternal dan internal. Persaingan dunia industri yang semakin ketat membutuhkan karyawan yang tidak hanya memiliki hardskill tetapi juga softskill. Tujuan penelitian ini untuk mengetahui pengalaman komunikasi mentor dan mahasiswa/i dalam meningkatkan hardskill dan softskill mahasiswa/i melalui program magang. Hasil penelitian ini mendeskripsikan bagaimana makna tindakan, ucapan dan interaksi yang mendasari aktivitas kepemimpinan mentor saat membimbing mahasiswa dalam program magang agar mengetahui pengalaman komunikasi yang di rasakan, hambatan komunikasi dan gaya komunikasi serta menumbuhkan keinginan dan keterbukaan mahasiswa untuk melakukan komunikasi dengan lingkungan baru yang dapat meningkatkan hardskill dan softskill.
Berbagi Pengetahuan Antar Organisasi Sektor Publik Dalam Rangka Kerjasama Inovatif Internasional
Authors: Rachmatsyah T. Herry
Published: October 2023

Studi ini bertujuan untuk memberikan wawasan baru dan berguna mengenai kerjasama internasional di sektor publik dan khususnya mekanisme berbagi pengetahuan melalui jaringan internasional. Mekanisme ini penting karena tidak hanya menjelaskan bagaimana dan mengapa terlibat dalam kerjasama internasional, namun juga menyoroti pentingnya berbagi pengetahuan dan mekanismenya dalam konteks internasional di sektor publik. Studi kasus eksplorasi kualitatif digunakan untuk mengumpulkan dan menganalisis data dari lima organisasi publik melalui wawancara semi terstruktur dilakukan terhadap delapan partisipan dari lima organisasi publik berbeda di lima negara berbeda. Hasilnya menunjukkan bahwa mekanisme berbagi pengetahuan yang berbeda dalam konteks internasional di sektor publik mengarah pada kerjasama inovatif internasional sebagai cara baru untuk bekerjasama dengan mitra internasional. Mekanisme ini dianggap mendasar untuk meningkatkan inovasi dan memperoleh pengetahuan baru yang berharga dari berbagai negara yang dapat membantu meningkatkan pelayanan publik.
Software and Hardware Bundle for Controlling a Group of Unmanned Vehicles Based on Robust Computer Vision Algorithms
Authors:   Saint Petersburg Electrotechnical University, Belov A. M. , Belyaev P. Yu. ,   Saint Petersburg Electrotechnical University, Viksnin I. I. ,   Saint Petersburg Electrotechnical University, Kim Yu. V. ,   Saint Petersburg Electrotechnical University, Radabolsky V. S. ,   Saint Petersburg Electrotechnical University, Turushev T. A. ,   Saint Petersburg Electrotechnical University, Chuprov S. S. ,   Saint Petersburg Electrotechnical University,   Golisano College of Computing and Information Sciences, Rochester Institute of Technology
Published: October 2023

The widespread adoption of automated robotic systems requires their confirmed efficiency and safety. To test these criteria, experimental testbeds that simulate an external environment under the conditions similar to the operating environment are developed. Systems focused on performing tasks under real conditions should be robust against the dynamic external environment. In this work, we develop a combination of software and hardware components for controlling a group of unmanned vehicles (UVs) based on computer vision algorithms that would be robust to external environmental factors. As part of our investigation, UV prototypes and their testing environment are developed. The action decision-making of each UV is based on a computer vision system, which incorporates algorithms for positioning, movement correction, other vehicle and obstacle detection. To verify the developed system, we conduct an empirical study into how the UV decisionmaking is affected by such external environmental factors, as changes in the level and tone of lighting, as well as the appearance of the surface. The experimental results show that the developed and implemented UV computer vision system meets the established robustness and stability requirements regardless of the tested environmental conditions. The developed system minimizes deviations from the planned route, reduces the localization error to 10 % at most, provides the accuracy of 84 % of other UVs detection, and maintains UVs operation without failures for two hours. The developed hardware and software bundle and testbed can be used for security and smart city control algorithms verification, as well as for other tasks requiring UVs prototyping.
Mathematical and Graph Models of Specialized Multi-Agent Systems with Distributed Solution of Applied Problems
Authors:   Bauman Moscow State Technical University, Chernousova T. G.
Published: October 2023

The concept of a specialized multi-agent system (SMAS) as a system designed for a distributed solution of either one applied problem or a highly limited range of applied problems is considered. Such problems frequently require a large number of homogeneous operations, which can lead to a significant increase in the size of the system and, as a result, to inefficient control and a drop in performance. Therefore, it is advisable to divide a large-sized open SMAS into classes of agents and find relationships between them. This corresponds to dividing the applied task T into subtasks and determining relations between these subtasks. Such a path entails a two-level distributed control over SMAS agents. At the first and second levels, respectively, the relations of agents within classes and between classes of agents are studied. This paper proposes a multi-model approach to constructing, modeling, and analyzing SMAS. The properties of the agent and its mathematical model, described by a 5-digit set, as well as the mathematical model of the class of agents, described by a 12-digit set, which includes such components as the collective knowledge base of agents, the collective communication environment, mental, social, and other components, are discussed. Relations between classes of agents are reflected in a mathematical model of open SMAS. If a partition of a problem T is represented by an undirected acyclic graph GR′ whose terminal vertices have degree one and whose interior vertices have degree two, then GR′ is defined as a simple tree. In the case when any class of agents is a complete graph К then the Cartesian product CP′ = GR′ × Kn, according to the proved theorem, is a graph model of an open SMAS, consisting of the components К and connectives between them. According to the corollary of this theorem, it is possible to pass from CP′ to the multigraph model MYL′ = (MV′, ME′) of the system, if the components К are associated with the vertices of this model mv′ com  MV′, and the connectives are associated with its edges me′ con1  ME′. Moreover, the number of edges between any two vertices MYL′ is equal to n. The analysis of multigraph models of open SMAS of large sizes will significantly reduce the complexity of their study at the structural level.
Investigation of the Principles of Operation of an Isolated Driver
Authors:   Saint Petersburg Electrotechnical University, Telnov A. A.
Published: October 2023

This paper studies the operational principles of isolated drivers of power transistors with the purpose of developing recommendations for the construction of protection systems. To this end, driver models were developed in the LTspice circuit simulator software. The models were different in term of galvanic isolation implementation, i.e., using either a transformer or an optocoupler. In the second half of the article, the work of a protection system aimed at restricting the limiting modes of operation of semiconductor key crystals is considered.
Mobile Echo Sounder Simulator
Authors:   Saint Petersburg State University of Architecture and Civil Engineering, Korotkov A. A. , Bukunov S. V. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: October 2023

A mobile application, designed to simulate real echo sounder, was developed at the Department of Information Technologies of the Saint Petersburg State University of Architecture and Civil Engineering (St. Petersburg, Russia). This application, potentially categorized as business software, can be used to test systems related to maritime navigation, as well as to create sea and river maps. The application is developed by C++ programming language using the cross-platform Qt library. The Graphic User Interface of the application is designed using the declarative programming language QML. The implementation of the mobile version of the application made it possible to refuse the use of additional communication devices to ensure communication between the simulator and the device under test.
Formation of the Interface Structure: Possible Optimal Problems
Authors:   Saint Petersburg Electrotechnical University, Paderno P. I. , Ryk D. D. ,   Saint Petersburg Electrotechnical University
Published: October 2023

Discusses the problems that arise in the process of interface design at the initial design stage. At this stage, the main necessary system functions and user scenarios are determined; additionally, a general interface structure is formed, intended for a generalized representation of the future interface, highlighting the main and secondary areas, objects, functions, which identifies the type and direction of connecting components and blocks, as well as a sequence of commands and actions. As a model, the design of the general interface structure is considered as the definition of a number (set) of rules that determine the importance and sequence of using the existing set of functional blocks, which are then treated as vertices of a digraph, while the need to provide (possibility) transitions from one block to another is treated as transitions between vertices of a digraph (arc). A thorough discussion is provided describing in detail the process of constructing a basic graph and determining the necessary parameters of vertices and arcs, based on the integrated use of the relevant experts’ knowledge (users and developers). A number of possible statements of unconstrained optimization problems on the resulting graph and their features are formulated and analyzed. The problems of conditional optimization on the obtained graph are defined and studied. The proposed approach and the solution of optimization problems at the appropriate stages will help to determine the most efficient structure of the interface designed from the point of view of the user and system capabilities, as well as under limited time and other resources to complete tasks.
Self-Organizing Neural Cellular Automata for Reinforcement Learning and Evolutionary Development
Authors:   Saint Petersburg Electrotechnical University, Mokretsov N. S. , Tatarnikova T. M. ,   Saint Petersburg Electrotechnical University
Published: October 2023

The relevance of studying self-organizing systems through the modeling of cellular automata is shown, which allows solving various problems from optimization and resource management to predicting the behavior of systems. A review of cellular automata is provided, including classical cellular automata, variational neural cellular automata, and growing developmental networks with neural cellular automata. The significance of using cellular automata in modeling complex processes that require the ability of the model to recover and retrain when the properties of an agent or environment change is discussed. In particular, it is shown that the introduction of self-organization into the model of reinforcement learning agents endows them with adaptability properties, which makes it possible to make changes to the original problem without additional retraining of the model and restore the system’s performance in case of damage to its structure. Examples of the use of cellular automata for modeling various processes and training agents are given.
Compressorless Temperature Control System
Authors:   Saint Petersburg Electrotechnical University, Lillo A. V. , Stotckaia A. D. ,   Saint Petersburg Electrotechnical University
Published: October 2023

To design a compressorless climate control system and study its characteristics, this work uses the methods of complex analysis and design of climate technology, experimental research, physical modeling, and mathematical calculations. A device has been designed to control temperature and humidity in a specialized storage. The systems features include the use of Peltier modules, hydraulic system, and low-potential earth energy. In the process of developing the system and studying the characteristics of its parts, as well as physical experiments using mock-ups of the units of the installation, satisfactory results have been obtained for continuing work and software and hardware implementation of the project. It is shown that individual parts of the system have the desired characteristics and are ready for a general study of the assembled installation.
Diagnostic Methods of the Stator Winding of Asynchronous Motors with a Squirrel-Cage Rotor
Authors:   Saint Petersburg Electrotechnical University, Baidiuk M. A. , Konstantinov K. V. ,   Saint Petersburg Electrotechnical University
Published: October 2023

Due to the widespread use of induction motors with a squirrel-cage rotor, the issue of increasing the reliability of machines of this type remains acute. According to statistics, the stator winding is the weakest node in terms of reliability. This article discusses various approaches to the diagnosis of the stator winding, which is seen as one of the main ways to improve the reliability of the machine. Such methods, as surge tests, monitoring of equivalent values of insulation parameters, diagnostics of partial discharges, and analysis of the response to a high-frequency discharge are analyzed. The advantages and disadvantages of each approach are discussed to identify the most promising methods.
Development of methods for controlling the quality of hypochlorous acid solution obtained by electrochemical synthesis
Authors: Brezvyn O. M. , Kotsiumbas I. Ya. , Hyrenko D. V. , Lukianenko T. V. , Shmychkova O. B. , Dmitrikova L. V. , Velichenko O. B.
Published: October 2023

The article presents materials on developing quality control methods for hypochlorite acid obtained by electrochemical synthesis. Electrochemical synthesis of hypochlorous acid was carried out using a combined electrochemical-pyrolytic method. The electrocatalytic activity of the obtained materials in the hypochlorite acid synthesis reaction was evaluated under the electrolysis of 0.05 M NaCl solutions in a duct cell with a Ti cathode at 25 ºС. The cathode area was varied, so the cathode current density was 40 mA/cm2. The pH of the solutions was monitored with a pX-150MI universal ionometer. The volumetric current density in the channel cell was 2.4 A/dm3, and the volumetric rate of solution supply was 9.5 l/h. The authors developed an original method of iodometric titration, which is based on the sequential determination of the content of hypochlorite ions, their total content with chlorite ions, and the total content simultaneously with chlorite and chlorate ions. The content of individual components of the mixture is determined as the difference between the total content of ions and the content of hypochlorite ions. The iodometric method of titration of oxidants is based on the reaction of replacing oxygen-containing compounds of chlorine with elemental iodine with its subsequent titration with standard solutions of sodium thiosulfate. It is proposed to fix the endpoint of the titration potentiometrically, which allows you to speed up the analysis, and it is also relatively easy to automate it using an automatic titrator. The content of oxygen-containing compounds in the solutions depends on the oxidation conditions and the specified operating modes of the electrochemical catalyst. The solution's acidity determines the presence of hypochlorous acid and can be calculated based on the equilibrium constant of its dissociation. The developed analysis methods will allow the control of the quality of veterinary drugs based on hypochlorous acid obtained by electrochemical synthesis.
Age and breed susceptibility of dogs to the causative agent of cystoisosporosis
Authors: Suvorov R. , Melnychuk V.
Published: October 2023

Cystoisosporosis refers to a protozoan parasitic disease caused by coccidia of the genus Cystoisospora canis in dogs, especially young ones. Pathogens are localized in the small intestine of animals and lead to an imbalance of microflora, indigestion, enteritis, and diarrhea. Knowledge of the epizootological features of this invasion makes it possible to carry out complex preventive measures more effectively and maintain well-being in certain territories. The research aimed to establish the dependence of the infection of dogs with the causative agent of cystoisosporosis on their age and breed. The conducted studies established that the age-related dynamics of cystoisosoporosis in the conditions of the city of Kharkiv were characterized by a decrease in the extent of infestation with the age of the dogs. The most affected were young animals up to 6 months of age, where the extent of infestation was 32.0 %. In dogs aged 6–12 months and 1–3 years, the extent of cystoisosporous infestation decreases to 18.9 and 4.7 %, respectively. Dogs aged 3 to 6 years and older than six were the least affected by cystoisospor oocysts, where the extent of infestation is 4.7 and 2.7 %, respectively. Breed susceptibility to cystoisosprosis is characterized by the most excellent infestation of mixed-breed dogs and purebred animals, where their average infestation was at the level of 22.0 %. Cystoisosporosis was less often diagnosed in dogs of hunting, service, and decorative breeds; the extent of infestation ranged from 10.3 to 14.3 %. In terms of breeds, the highest infestation by protozoan organisms was found in labrador retrievers (extensive infestation 6.0 %), German shepherds (3.9 %), dachshunds (3.5 %), Yorkshire terriers (3.2 %) and cocker spaniels (2.8 %). The obtained data allow us to take into account the obtained results regarding the age and breed susceptibility of dogs to coccidia of the genus Cystoisospora for timely diagnosis and prevention of cystoisosporosis.
Study of Aspir-35 toxicity
Authors: Kaliuzhna T. M. , Fotina H. A.
Published: October 2023

Preclinical research on veterinary pharmaceuticals is crucial and required when creating new dosage forms. Preclinical research aims to ascertain the test substance's therapeutic efficacy, toxicity, future dose form, impact on the body's fundamental systems, and identification of potential side effects. The objective of this study was to assess the potential toxicity of Aspir-35 following short- and longer-term exposure in rats. The acute toxicity of the drug was studied on 30 white mice weighing 18–20.5 g and 15 white rats weighing 180–215 g. The animals were kept in a vivarium in accordance with sanitary rules and on a standard diet taken in the vivarium using compound feed. The drug “Aspir-35” was administered to rats and mice once in the morning on an empty stomach orally through a probe with a cannula in doses of 1250, 2500 and 5000 mg/kg of body weight. Animal feeding was started two hours after drug administration. The study of the toxicity of the drug “Aspir-35” during long-term subcutaneous administration was studied on rats with an initial body weight of 180–230 g divided according to the principle of analogues into two groups of 6 heads each. The animals were kept in similar conditions as in the study of the acute toxicity of the drug. The drug “Aspir-35” was administered to the rats of the experimental group subcutaneously daily for 18 days at a dose of 0.5 ml/kg of body weight. The drug “Aspir-35” did not cause the death of experimental rats and mice when administered once orally in doses of 1250, 2500 and 5000 mg/kg of body weight. On this basis, the drug “Aspir-35” can be attributed to the 4th class of danger according to the International Standard GOST 12.1.007-76, or to category 5 according to the International Global Classification of the Global Harmonized System, (GHS), since the LD50 of the drug “Aspir-35” when taken orally will exceed 5000 mg/kg of body weight. The drug “Aspir-35” in a dose of 0.5 ml/kg of body weight when administered subcutaneously for 18 days did not cause negative and harmful effects on the body of experimental rats, did not affect their growth and development, did not cause changes in the relative weight of internal organs and did not led to changes in hematological indicators in experimental animals. The analysis of the results of the conducted research indicates the relative harmlessness of the potential drug for veterinary medicine and allows us to predict that the drug “Aspir-35” can be classified as a low-risk substance, which justifies the feasibility of its further study and implementation in practice.
The Lifestyle and Mobility Connection of Community Supported Agriculture (CSA) Users
Authors: Nahas Nathalie , Lachapelle Ugo
Published: October 2023

Because Community Supported Agriculture (CSA) is considered a greener food shopping option, we hypothesized that users would adopt other sustainability-oriented behaviors. We sought, through 16 qualitative interviews with users, to understand whether CSA use in Montreal, Canada was accompanied by more ecological, non-motorized travel behavior. We find that urban users are typically able to subscribe to a nearby drop-off point and that many of them use non-motorized modes to access their weekly baskets. However, because of the weight of large produce baskets and the set time periods for collection, basket pick-ups by new Covid-19 era users are often part of car-based trip chains.
IUCN Red List of Ecosystem assessment: Tropical glacier ecosystem of the Cordillera de Mérida
Authors: Ferrer-Paris José , Llambi Luis , Melfo Alejandra , Keith David
Published: October 2023

This document uses the IUCN Red List of Ecosystems guidelines to diagnose the collapse of the Tropical glacier ecosystems of the Cordillera de Mérida in Venezuela.Tropical glaciers are rapidly disappearing, particularly in isolated mountain peaks and lower elevations. These glaciers are fundamental substrates for unique cryogenic ecosystems in tropical environments where the ice, melting water and rocky substrate sustain microbiological communities and other meso- and macro-biota. The IUCN Red List of Ecosystems assessment protocol provides a valuable framework for comparative analysis of threatened ecosystems. We undertook the assessment with existing data derived from field observations and samples, literature review, cartographic reconstruction, remote sensing products and climatic models, and complemented these with additional statistical analysis and modelling to calculate and predict rates of decline and relative severity of degradation. The evidence suggests an extreme risk of collapse (Critically Endangered) due to prolonged and acute declines in ice extent and changes in climatic conditions that are leading towards a complete loss of ice mass. The biotic compartments of the glacial ecosystem will consequently be lost, with ice loss also initiating a decades-long succession of forefield vegetation. Even the most optimistic climate change projections are unlikely to prevent imminent ecosystem collapse in this region.
Factors Affecting the Adjustment to College Life of Freshmen Students of College of Business and Accountancy
Authors: Sumicad Rulthan , Geraldizo-Pabriga Maria Gemma , Geraldizo Jr. Benjamin P. , Quiñal Jr. Pedro O.
Published: October 2023

This research identified the factors influencing the adjustment to college life among freshmen students, specifically focusing on those enrolled in the College of Business and Accountancy. The findings of this study will serve as the foundation for an actionable plan to be presented to the University of Cebu's administration department. A descriptive-correlational research method was employed, utilizing data from the Freshmen Interaction Form gathered over the past decade. The research uncovered a significant correlation between the factors impacting freshmen students' adjustment to college life and their gender. Among freshmen in the College of Accountancy, these factors were found to be linked to their biological sexual orientation. Notably, factors such as Personal, School-Related, Interpersonal, and financial aspects were identified as the primary influencers on the adjustment of first-year students within the College of Business and Accountancy. This study sheds light on the nuanced nature of college adjustment factors, especially among students pursuing business and accountancy degrees, and provides valuable insights for enhancing the support systems and services offered by the University of Cebu.