bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of CSM–CERES–Rice in scheduling irrigation and simulating effect of drought stress on upland rice yield
Authors: Hussain T , Anothai J. , Nualsri C . , Soonsuwon W
Published: April 2018

Crop models can provide rapid and cost effective means to deal with rice crop management. The objectives of this study included, exploring the ability of CSM–CERES–Rice in scheduling irrigation and to simulate the effect of drought stress on upland rice yield. Irrigation treatments 100, 70 and 50 % of field capacity (FC) were applied from 80 days after planting (DAP) at flowering stage until maturity and CSM–CERES–Rice was used to predict irrigation amount for each water regime for treatment duration. Results showed that, at 70 and 50 % FC, performance of an upland rice genotype, Dawk Pa-yawm was decreased significantly as compared to 100 % FC. Normalized root mean square error (RMSEn) values less than 10 % for each treatment indicated a strong agreement between simulated and observed grain yield (GY) and biomass. d-index approaching to unity and RMSEn less than 10 % indicated a good agreement between simulated and observed soil moisture contents (SMC) for all irrigation treatments. Overall, it was concluded that drought stress had negative correlation with GY and CSM–CERES–Rice was able to predict irrigation amount for all treatments assuring that, model has potential for its use as a tool to schedule irrigation for experiments under water limited conditions.
Biology and development of Sitophilus oryzae L. feeding on split pulses
Authors: Vijay S , Bhuvaneswari K.
Published: April 2018

An experiment was carried out at the Entomology Laboratory, Horticultural College and Research Institute for Women, Trichy in November- December 2013 to study the biology and development of Sitophilus oryzae L. under laboratory conditions. Observations were made on oviposition rate, total number of eggs, adult emergence per 100 grains, egg to adult survival percentage, adult longevity, adult emergence period and reproductive potential. The oviposition rate per female (9.43 nos), total number of eggs (94.30 nos), adult emergence per 100 grains (38.50 nos), reproductive potential (35.50 nos), egg to adult survival percentage (41.85), adult female longevity (12.88 weeks) and adult male longevity (8.33 weeks) were higher in redgram under room temperature condition feeding by the respective population as compared to controlled condition. In case of sorghum, all the above parameters were superior to redgram feeding by the respective population under room and controlled temperature condition. The larval (26.13 days), pupal (7.63 days) and adult emergence period (33.75 days) was maximum in lentil under room temperature as compared to controlled condition. In case of sorghum, larval, pupal and adult emergence period was minimum when compared to split pulses feeding by the respective population irrespective of temperature and humidity.
Response of clusterbean varieties to various inter and intra row spacings in rainfed alfisols
Authors: Kumari C Radha , Reddy B Sahadeva
Published: April 2018

A field experiment was conducted to study the influence of spacing on clusterbean varieties in alfisols of scarce rainfall zone under rainfed situation for consecutive three kharif seasons of 2013, 2014 and 2015 at the Agricultural Research Station, Ananthapuram of Andhra Pradesh. Pooled data revealed that higher yield was recorded with branched varieties (447 kg ha-1) than unbranched varieties (445 kg ha-1). Unbranched variety produced higher haulm yield. Among crop geometry, 22.5 x 10 cm recorded higher seed yield of 512 kg ha-1 while lowest seed yield of 393 kg ha-1 obtained with 45x10 cm. Among crop geometry tested, higher haulm yield was registered with 45x7.5 and 22.5x7.5 cm spacing resulted lowest haulm yield. Considering the economics and large scale availability of seed drills and planters with farmers sowing of cluster bean either branched or unbranched genotypes with 30 x 7.5 or 10 cm spacing was found optimum.
Status of available sulphur and cationic micronutrients in cultivated soils of Banaskantha district of Gujarat
Authors: Desai Dipali , Patel B T , Chaudhary Neha , Thakur Praveen
Published: April 2018

In order to assess the available sulphur and micronutrients (Fe, Mn, Zn and Cu) status in soils of Banaskantha district of Gujarat, five hundred and fifty six representative surface (0-15cm) soil samples were collected from farmer’s field of each taluka of Banaskantha district. All the collected soil samples were analyzed for available sulphur and DTPA-extractable cationic micronutrients (Fe, Mn, Zn and Cu) as per standard procedures. The available S content in soils of Banaskantha district varied from 4.98 to 66.89 mg kg-1 with a mean value of 15.49 mg kg-1. The DTPA- extractable Fe, Mn, Zn and Cu were in the range of 2.74 to 21.98; 4.22 to 25.02; 0.20 to 2.76 and 0.12 to 3.16 mg kg-1 with a mean value of 6.72, 10.15, 0.60 and 0.60, respectively. The overall nutrient index values were marginal for available S (1.82) and DTPA-extractable Fe (1.84) and Zn (1.74); high for DTPA-extractable Mn (2.40) and very high for Cu (2.75).
Antimicrobial Stewardship in Neonates: Challenges and Opportunities
Authors: McPherson Christopher , Liviskie Caren , Zeller Brandy , Nelson Miranda P. , Newland Jason G.
Published: April 2018

Neonatal infections result in significant morbidity and mortality. Antibiotics are vital for the treatment of infections but disrupt the neonatal microbiome, put the infant at risk for an adverse drug reaction, and may lead to the development of antibiotic resistance. Immediately after birth, clinicians must determine which infants require empiric antibiotics. Online risk stratification tools may provide a superior approach to decision trees. In infants who require empiric therapy for early-onset sepsis, ampicillin and an aminoglycoside with dosing based on recent pharmacokinetic studies represents the most appropriate first-line agents; third-generation cephalosporins should be reserved for patients with a high likelihood of Gram-negative meningitis. An antistaphylococcal penicillin and gentamicin should be utilized for suspected late-onset sepsis. Vancomycin and other broad-spectrum agents are reserved for patients with a history of resistant organisms. Antibiotic duration should be guided by understanding the clinical indications and obtaining the necessary cultures appropriately (i.e., adequate volume blood cultures). In the absence of a positive culture, antibiotic duration should often be limited. Individual institutions should leverage a multidisciplinary, interprofessional team to identify opportunities for antimicrobial stewardship. A collaborative, transparent system is required to change unit culture and generate a sustained impact on antibiotic utilization with optimal patient outcomes.
Structured Educational Intervention Leads to Better Infant Positioning in the NICU
Authors: Masri Saadieh , Ibrahim Perla , Badin Daniel , Khalil Samar , Charafeddine Lama
Published: April 2018

Purpose

The purpose is to test the effectiveness of an educational intervention in improving infant positioning because positioning may interfere with neuromotor development.

Methods

A quality improvement (QI) project was initiated to increase knowledge and improve the compliance of nurses and physicians in infant positioning using the Infant Positioning Assessment Tool (IPAT). The project was part of Neonatal Individualized Developmental Care Assessment Program (NIDCAP) training. It included informal discussion and practice about infant positions.

Main Outcome Variables

Staff knowledge, IPAT score.

Results

Fifty-two pediatric residents and 39 NICU nurses participated in this project. The mean knowledge assessment test score improved significantly for both nurses (p< .0001) and residents (p< .0001) postintervention; IPAT scores increased significantly from 3.4 (±2. 5) to 8.1 (±2.7) (p< .001).

Conclusion

Nurses’ education with hands-on practice improved infant positioning in the NICU; this may lead to fewer positional deformities and possibly an improved developmental outcome.
The History and State of Neonatal Nursing Quality Improvement Practice and Education
Authors: Kukla Aniko , Dowling Donna A. , Dolansky Mary A.
Published: April 2018

Quality improvement has evolved rapidly in neonatal nursing. This review outlines the history and current state of quality improvement practice and education in neonatal nursing. The future of neonatal nursing includes a stronger emphasis on quality improvement in advanced practice education that promotes doctoral projects that result in clinical improvements. A collective focus will ensure that neonatal nurses not only deliver evidence-based care, but also continually improve the care they deliver.
Promoting Newborn Safety Using the RAPPT Assessment and Considering Apgar Criteria: A Quality Improvement Project
Authors: Ludington-Hoe Susan M. , Morrison-Wilford Barbara L. , DiMarco Marguerite , Lotas Marilyn
Published: April 2018

Purpose

The aim of this project was to evaluate the implementation of the Respiratory, Activity, Perfusion, Position, and Tone (RAPPT) instrument in assessing the infant’s transition to extrauterine life while in skin-to-skin contact (SSC).

Sample/Design

Nurses (n= 17) completed a pretest and posttest of RAPPT and Apgar scoring knowledge, attended an in-service about accurate scoring, and were observed during 17 deliveries when newborns were in SSC.

Outcome Variables

Primary variables were knowledge scores, use of RAPPT, and accurate RAPPT scoring. Apgar scoring was also measured.

Results

Knowledge scores increased significantly after education, RAPPT scores were correctly assessed, and 1 of 17 newborns had a sudden unexpected postnatal collapse. Apgar scoring accuracy did not change and nurses reported that their Apgar scores were based on their overall impressions of the infant instead of Apgar criteria.
Implementing a Systematic Process for Consistent Nursing Care in a NICU: A Quality Improvement Project
Authors: McCarley Renay Marie , Dowling Donna A. , Dolansky Mary A. , Bieda Amy
Published: April 2018

Aim

The global aim of this quality improvement project was to develop and implement a systematic process to assign and maintain consistent bedside nurses for infants and families.

Methods

A systematic process based on a primary care nursing model was implemented to assign consistent care for a 48-bed, single-family room NICU.

Results

Four PDSA cycles were necessary to obtain agreement from the nursing staff as to the best process for assigning primary nurses. Post-intervention data revealed a 9.5 percent decrease of consistent caregivers for infants in the NICU ≤ 28 days and a 2.3 percent increase of consistent caregivers for infants in the NICU ≥ 29 days.

Conclusion

Although these findings did not meet the goal of the specific aim, a systematic process was created to assign bedside nurses to infants. Further PDSAs will be needed to refine the process to reach the aim.
Hidradenocarcinoma do Escroto com Metastização Ganglionar
Authors: Simões Maria Inês , Marcão Isabel , Toscano Mário , Borges Luís
Published: April 2018

O hidradenocarcinoma é uma neoplasia rara das células écrinas das glândulas sudoríparas, geralmente assintomática e de crescimento lento, com maior incidência entre os 50 e os 80 anos, atingindo ambos os sexos e com localização preferencial nas regiões palmar, plantar, frontal, axilar e nuca. Tem um comportamento agressivo, com alta taxa de recorrência local e metastização à distância, associando-se a mau prognóstico. Apresentamos um caso raro de hidradenocarcinoma do escroto manifestado por metastização ganglionar justificando exercício de diagnóstico diferencial clínico e histológico de adenopatia inguinal num adulto jovem.
Association of Anger Expression-Out with NK Cell Counts in Colorectal Cancer Patients
Authors: Kakoo-Brioso Estela , Costa Luís , Ouakinin Sílvia
Published: April 2018

Introduction: There is growing evidence describing the relation between psychological factors and the progression of colorectal cancer. Several mechanisms have been proposed but the one showing more promising evidence relies on the modulation of the antitumoral immune response by psychological factors, particularly through natural killer cells. We aimed to study the relation between natural killer cell count and anxiety, depression and anger state, trait and expression in 54 pre-surgical colorectal cancer patients.Material and Methods: We measured peripheral blood natural killer cell count and applied the State-Trait Anger Expression Inventory and the Hospital Anxiety and Depression Scale to 54 pre-surgical colorectal cancer patients. We used the Mann-Whitney U test and the Kruskal-Wallis test when appropriate to compare independent groups.Results: Patients with higher Anger Expression-Out had lower natural killer cell numbers than patients with lower Anger Expression-Out (p value = 0.008). No relation was found between natural killer cell levels and Anger State, Anger Trait, or Anger Expression-In. No difference in natural killer cell count was found between patients with and without clinical anxiety or depression.Discussion: These results suggest that, in colorectal cancer patients, natural killer cell counts are influenced by Anger Expression-Out, but not by clinical anxiety or depression.Conclusion: The unregulated emotional expression might be a conditioning factor of innate immunity. Additional studies are needed to further investigate this relation and to ascertain the clinical impact of therapeutic interventions regarding emotional regulation on the anti-tumoral immune response.
EP4 as a Therapeutic Target for Aggressive Human Breast Cancer
Authors: Majumder Mousumi , Nandi Pinki , Omar Ahmed , Ugwuagbo Kingsley Chukwunonso , Lala Peeyush K.
Published: April 2018

G protein-coupled receptors (GPCRs, also called seven-transmembrane or heptahelical receptors) are a superfamily of cell surface receptor proteins that bind to many extracellular ligands and transmit signals to an intracellular guanine nucleotide-binding protein (G protein). When a ligand binds, the receptor activates the attached G-protein by causing the exchange of Guanosine-5'-triphosphate (GTP) for guanosine diphosphate (GDP). They play a major role in many physiological functions as well as in the pathology of many diseases including cancer progression and metastasis. Only a few GPCR members have been exploited as targets for developing drugs with therapeutic benefit in cancer. Present review deals with the Prostaglandin E receptor EP4, a member of the EP family of GPCR, as a promising newer therapeutic target for treating breast cancer. We show that aberrant over-expression of cyclooxygenase (COX)-2, an inflammation-associated enzyme, occurring in 40-50% of breast cancer patients leads to tumor progression and metastasis due to multiple cellular events resulting from an increased prostaglandin (PG) E2 production in the tumor milieu. They include inactivation of host anti-tumor immune (NK and T) cells, increased immuno-suppressor function of tumor-associated macrophages, promotion of tumor cell migration, invasiveness and tumor-associated angiogenesis (due to upregulation of VEGF-A), lymphangiogenesis (due to upregulation of VEGF-C/D) and a stimulation of stem-like cell (SLC) phenotype in cancer cells. All these events were primarily mediated by activation of the PGE receptor EP4 on tumor or host cells. We show that selective EP4 antagonists (EP4A) could mitigate all these events tested with cells in vitro as well as in vivo in syngeneic COX-2 expressing mammary cancer bearing mice or immune-deficient mice bearing COX-2 over-expressing human breast cancer xenografts. We suggest that EP4A can avoid thrombo-embolic side effects of long term use of COX-2 inhibitors by sparing cardio-protective roles of PGI2 via IP receptor activation or PGE2 via EP3 receptor activation. Furthermore, we identified two COX-2/EP4 induced oncogenic and SLC-stimulating microRNAs - miR526b and miR655, one of which (miR655) appears to be a potential blood biomarker in breast cancer patients, for monitoring SLC-ablative therapies such as with EP4A. We suggest that EP4A will likely produce the highest benefit in aggressive breast cancers such as COX-2 expressing triple-negative breast cancers, when combined with other newer agents such as PD-1 or PD-L1 inhibitors.
Maniobras claves y trucos en eTEP
Authors: Palmisano Ezequiel Mariano , Martínez Juan David , Magdaleno Garcia Miguel , Gonzalez Luis Gabriel
Published: April 2018

Introducción: El abordaje TEP podría ser la opción ideal para reparar las hernias inguinales, pero tiene como limitaciones un campo quirúrgico reducido y una disposición restringida de los puertos de trabajo. Para superar estos problemas se ha descrito la modalidad extendida (eTEP) que amplía el campo quirúrgico y permite una mayor flexibilidad en el posicionamiento de los puertos de trabajo. El objetivo de este trabajo es revisar esta modalidad de abordaje como alternativa para tratar las hernias inguinales.Método: Revisión sistemática basada en las bases de datos Cochrane, Google, Embase y Medline usando PubMed, sin restricciones y usando como palabra clave: técnica totalmente extraperitoneal extendida.Resultados: Se describe la experiencia actual con el abordaje extendido y sus pasos técnicos para una correcta creación del espacio y posterior colocación de trócares.Conclusión: Nuestra evaluación multicéntrica de la técnica de acceso eTEP para reparar las hernias inguinales ha encontrado que el abordaje es factible y efectivo. Este nuevo enfoque ofrece una configuración más óptima para tratar un mayor número de hernias inguinales mediante laparoscopia.
Combinación de toxina botulínica A y neumoperitoneo preoperatorio progresivo abreviado como técnica adyuvante para la reparación de grandes hernias de la región inguinal. Reporte de un caso.
Authors: Palmisano Ezequiel Mariano , Pérez Grassano Andrés , Schmidt María Laura
Published: April 2018

Introducción. El tratamiento de las hernias inguinales gigantes representa un verdadero desafío terapéutico. Todavía no existe un consenso sobre la mejor forma de preparar a estos pacientes. El objetivo de éste trabajo es reportar un caso donde se utiliza de forma combinada el efecto de la toxina botulínica A y el neumoperitoneo preopertorio progresivo abreviado, como técnica adyuvante preoperatoria.  Caso clínico. Varón de 76 años con hernia inguinal gigante sintomática. Estudio de tomografía preoperatorio para medir espesor y longitud de la pared abdominal lateral y diámetro transverso máximo de la cavidad abdominal. Preparación con toxina botulínica A y a los 14 días con neumoperitoneo durante 7 días. Control de tomografía tras previo a la cirugía. Resultado. Se muestran los datos de modificación de la pared abdominal tras la preparación. La reparación quirúrgica fue una hernioplastia tipo Lichtenstein y no se registraron complicaciones.Conclusión. El uso combinado de toxina botulínica y neumoperitoneo como técnica adyuvante en los casos de hernias inguinales gigantes aumenta el volumen de la cavidad abdominal y facilita la técnica quirúrgica.
Anatomía quirúrgica de la pelvis femenina (con especial atención al tejido conectivo)
Authors: Kock Erwin
Published: April 2018

Introducción. Las características anatómicas de las fascias de la pelvis han sido descritas e interpretadas de forma distinta por anatomistas y cirujanos. Actualmente, todavía no sabemos cuál de dichas anatomías es la verdadera. El objetivo de este estudio es describir las fascias y espacios de la pelvis femenina e interpretar la anatomía desde una perspectiva quirúrgica.Material y Método. Estudio realizado en 29 cadáveres humanos, entre los años 2010 y 2015, en la Universidad de Tucumán, Argentina. Los cadáveres fueron disecados siguiendo la técnica quirúrgica habitual. Las vías  de abordaje  fueron superior, inferior o perineal, disección  de cortes sagitales, vertico-frontales y horizontales, y resección en bloque del contenido pelviano y su posterior preparación - disección.                  Resultados.  Se describe el diafragma aponeurótico y muscular, los espacios regionales, láminas y fijaciones de la pelvis femenina.Conclusión. La disposición anatómica de la pelvis femenina presenta como estructuras fasciales: 1) lámina iliogenital, 2) lámina interuretérica, 3) fascia de cubierta del espacio perirectal, 4) fascia de cubierta del espacio perivesical, 5) diafragma pelviano aponeurótico y 6) lámina perivisceral interdiafragmática. Y como espacios delimitados por estas fascias los siguientes: I) espacio perivesical, II) espacio perirectal, III) espacio intermedio, IV) espacio vesicogenital, V) espacio rectogenital y VI) el espacio interdifragmático.Palabras clave: pelvis femenina; anatomía; lámina iliogenital; periné
Pseudoquiste de pared abdominal: tratamiento con presión negativa. A propósito de un caso
Authors: Sánchez Natalia Josefina , Roche Sebastiàn , Bertone Santiago , Cetolini Fernando Emanuel , Brandi Claudio Dario
Published: April 2018

Introducción: La eventración constituye la complicación tardía más común de la cirugía abdominal. Una complicación poco frecuente de su reparación con material protésico lo constituye el pseudoquiste fibroso gigante de pared. En cuanto al tratamiento, la punción evacuadora solo es una solución transitoria, por lo que la cirugía con la resección completa del pseudoquiste se considera el tratamiento de elección.Caso clínico: Se presenta un caso clínico cuyo tratamiento consistió en un sistema de vacío y compactación.Discusión: El pseudoquiste es una complicación poco frecuente tras la reparación de una hernia incisional con prótesis. El tratamiento de elección es la resección total del mismo. Los sistemas de vacío y compactación pueden considerarse una alternativa de tratamiento, en casos recidivados.
Anatomía quirúrgica del músculo transverso abdominal y sus aponeurosis: consideraciones quirúrgicas para reparar la pared abdominal
Authors: Moreno Egea Alfredo
Published: April 2018

Introducción. El músculo transverso abdominal es el más desconocido de la pared abdominal para la mayoría decirujanos. Las nuevas técnicas quirúrgicas de reparación de la pared mediante separación de componentes necesitanconocer la anatomía especial de este músculo. Este trabajo describe la anatomía del músculo transverso y sus aponeurosis,como base para la cirugía reparadora de la pared abdominal.Material y métodos. Estudio prospectivo diseñado sobre 10 cadáveres disecados en la Cátedra de Anatomía de laFacultad de Medicina de la Universidad Católica de Murcia. Diez preparaciones del músculo transverso abdominalfueron separadas de sus conexiones regionales de forma cuidadosa y mantenidas en formol. Se grabaron todas lasdisecciones. Las piezas se fotografi aron y registraron para su posterior valoración.Resultados. Se verifi can las fi jaciones íntimas que el músculo transverso mantiene con las estructuras regionalesadyacentes. Se comprueba el cierre abdominal que asegura a nivel vertebral, costolumbar e ilíaco, y el papel de sus dosaponeurosis de inserción en la contención abdominal.Conclusiones. 1) El músculo transverso es el único en la pared abdominal que es completamente aponeurótico,anterior y posterior. 2) La integridad de la aponeurosis posterior del transverso asegura un cierre completo costoiliovertebral.3) Las aponeurosis del cuadrado lumbar y de los oblicuos son de cubierta, no útiles para el cirujano. 4) Laintegridad del músculo transverso garantiza la contención del abdomen; su sección debería seguirse de su reinserciónpara alterar toda la pared abdominal.
¿Mayúscula o minúscula inicial? (III): Nombres de enfermedades con antropónimo
Authors: Aguilar Manuel
Published: April 2018

Carta al director
¿Mayúscula o minúscula inicial? (I): Los nombres de enfermedades
Authors: Aguilar Manuel José
Published: April 2018

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In memoriam: Dr. Daniel Alfredo León (1959-2017)
Authors: Cano Carlos Alberto
Published: April 2018

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Actinomicosis primaria de pared abdominal: presentación de un caso con fístula enterocutánea y revisión de la bibliografía
Authors: López Casillas Nelson , Cuevas González Aarón
Published: April 2018

La actinomicosis es una infección causada por las bacterias del género Actinomyces; sus formas de presentación más comunes son la cervicofacial (50 %), la torácica (30 %) y la abdominal (20 %).Presentamos el caso de una mujer de 45 años con el antecedente de DM2 y uso de DIU durante 5 años. Presentaba un cuadro clínico insidioso con dolor abdominal crónico y posteriormente tumoración de pared abdominal en mesogastrio y fl anco izquierdo, con descarga de material seropurulento, escaso por solución de continuidad en la pared abdominal.La actinomicosis de pared abdominal es una enfermedad infecciosa rara, origen de abscesos y fístulas enterales espontáneas no relacionadas con neoplasias. Su diagnóstico preoperatorio es todo un reto. El tratamiento se basa en antibioticoterapia con betalactámicos, macrólidos y tetraciclinas. El tratamiento quirúrgico se reserva en caso de complicaciones.
Manejo multimodal de la eventración gigante
Authors: Juárez Muas Derlin
Published: April 2018

Antecedentes: La eventración gigante es una patología que afecta la calidad de vida de los pacientes, con altos índices de morbimortalidad y recidiva. Una correcta planificación prequirúrgica mejora las condiciones para la cirugía. El uso de descargas musculares y doble malla aumenta la seguridad de la eventroplastia. Objetivo: Describir el manejo multimodal de las eventraciones gigantes. Diseño: Estudio retrospectivo.Material y métodos: Presentamos dos pacientes mujeres con eventraciones gigantes manejadas con toxina botulínica A, neumoperitoneo preoperatorio, separación anatómica de componentes (a una anterior y a otra posterior) y eventroplastia con doble malla. Resultados: A ambas pacientes se les infiltró toxina botulínica tipo A (100 UI). A los 15 días se les efectuó neumoperitoneo preoperatorio progresivo durante 20 días. Se les realizó resección de cicatriz previa (diéresis por planos) y apertura y tratamiento del saco y se creó plano retrorrectal. En una paciente se efectuó descarga del oblicuo externo a lo Albanese bilateral, y en la otra, descarga del músculo transverso bilateral. Se efectuó cierre de aponeurosis posterior, se colocó malla de polipropileno pesado retromuscular y se fijó al pubis-Cooper, EIAS y transmuscular. Se cerró aponeurosis anterior, se colocó una segunda malla preaponeurótica de polipropileno liviano macroporoso y se fijó con sutura absorbible. Se dejaron drenajes prefasciales. Síntesis por planos. Se colocó faja en quirófano. El tiempo quirúrgico promedio fue de 217 minutos. Tuvieron buena evolución posquirúrgica, con alta hospitalaria a las 96 h y retorno laboral a los 30 días. Seguimiento PO de 14 meses, sin complicaciones ni recidiva clínico-ecográfica.Conclusiones: El manejo multimodal de las eventraciones gigantes permite a los pacientes llegar en mejores condiciones quirúrgicas. La toxina botulínica, el neumoperitoneo preoperatorio y las descargas musculares aumentan el porcentaje de restitución de la línea media sin tensión, minimizando el riesgo de hipertensión intraabdominal posoperatoria. La colocación de doble malla aumenta la seguridad de la plástica y disminuye la recidiva en pacientes con defectos complejos de la pared abdominal.
Anatomía quirúrgica de los pilares del diafragma: consideraciones técnicas para la reparación de la hernia hiatal esofágica
Authors: Moreno Egea Alfredo
Published: April 2018

Introducción. Los pilares de la porción lumbar del diafragma conforman el hiato aórtico y esofágico. La constitución de estos pilares es todavía controvertida en cuanto a su origen, disposición y relaciones. El objetivo de este estudio es analizarla anatomía de los pilares del diafragma, la configuración del hiato esofágico, como base para la reparación de la hernia hiatal.Material y método. Estudio prospectivo diseñado sobre 10 cadáveres disecados en la Cátedra de Anatomía de la Facultad de Medicina de la Universidad Católica de Murcia. Diez preparaciones del diafragma completo fueron separadas de sus conexiones regionales de forma cuidadosa y mantenidas en formol. Todas las disecciones fueron grabadas, y las piezas, fotografiadas y registradas para posterior valoración.Resultados: La separación del diafragma es imposible sin seccionar sus fijaciones con el músculo transverso abdominal. La porción lumbar se fusiona con la aponeurosis del transverso abdominal y con la vaina anterior de la fascia lumbodorsal. El hiato esofágico está formado exclusivamente por fibras del pilar derecho en el 70 % de los casos. En el otro 30 % participa el pilar izquierdo mediante un pequeño manojo de fibras poco consistentes que lo alcanza por detrás. El músculo de Low fue disecado en el 20 % de los casos.Conclusiones. 1) El diafragma forma unidad anatómica con el músculo transverso abdominal. 2) El hiato esofágico se forma habitualmente por la decusación del pilar derecho. El pilar izquierdo rara vez forma parte del hiato. 3) La alta variabilidad en la anatomía de los pilares desaconseja la sutura. 4) La reparación del hiato esofágico y del diafragma en general debería realizarse con el apoyo de una malla.
Infección protésica crónica asociada a extrusión tras hernioplastia umbilical
Authors: Viscido Germá , Biurrum Chamale Javier , Bocco Anastasía María Cecilia , Olmedo Ignacio , Picón Molina Héctor , Mandojana Facundo , Parodi Matías , Palencia Rafael , Doniquian Alejandro
Published: April 2018

La hernioplastia incisional es una de las cirugías más frecuentes que realiza un cirujano general. La utilización deprótesis durante la reparación de estos defectos ha mostrado excelentes resultados, con disminución en el porcentaje derecidivas. La infección protésica crónica es una complicación relativamente infrecuente pero grave, y que causa preocupaciónen el paciente y en el equipo médico y aumento de los costos en salud, y enlentece la reincorporación laboraly la recuperación de la calidad de vida del paciente, entre otras cosas. El tratamiento varía desde el manejo conservadorhasta el retiro de la malla infectada. Presentamos un caso de infección de herida crónica asociada a extrusión protésicatras hernioplastia incisional cuya resolución fue quirúrgica.
Hernia traumática aguda de la pared abdominal: reparación laparoscópica. Reporte de un caso y revisión bibliográfi ca
Authors: Pereira Warr Salín , Correa Cote Juan Camilo , Mejía Toro David A. , Jurado Muñoz Paula A.
Published: April 2018

Las hernias traumáticas aguda de la pared abdominal es un tipo raro de hernia y el tratamiento ha sido controversial.La vía de abordaje puede ser abierta o laparoscopica, la cual depende de las lesiones asociadas y el entrenamiento delcirujano. Los accidentes viales son la causa más común y su corrección puede ser un reto. Presentamos un caso dehernia traumática aguda de la pared abdominal con reparación exitosa vía laparoscopica y revisión de la literatura.
Pengaruh Waktu Pemupukan pada Dua Musim Tanam terhadap Karakter Wijen Sbr-1 dan Sbr-3 di Lahan Pasir Pantai
Authors: Nurhayati Dewi Ratna , Yudono Prapto , Taryono Taryono , Hanudin Eko
Published: April 2018

Sesame is recognized as healthy potential oil crops because can be used to control several diseases. Sesame can grow properly in light soil structure such as sandy coastal soil, however sandy soil is considered as unfertile one and therefore environmental friendly fertilizer application based on dung manure must be studied. The research toinvestigate the influence of application times of mixed fertilizer on the growth sesame in quality growth in coastal sandy soil both at rainy and dry seasons, therefore the experiment directly to the sandy field at the sandy coastal area of Keburuhan, Purworejo, Central Java. From the first stage, it could be said that the application of mixed fertilizer between chicken manure and inorganic fertilizer increasing tochlorophyll content, net assimilation rate, root volume sesame both in rainy and dry seasons.
The Potential of Outing Class Acitivities to Enhance Environmental Awareness for Elementary School Pre-Services Teacher
Authors: Patonah Siti , Rahardjo Sentot Budi , Cari Cari , Sajidan Sajidan
Published: April 2018

Environmental damage in various places requires concrete steps to be resolved. The purpose of this research is to make environmental awareness work for Elementary School Pre-services Teacher through outing class activities. Post-test only group design is used as a method of this research. The instruments used are environmental awareness questionnaire where adapted. There are 71 elementary pre-service teacher  (60 male and 11 female) who fill in questioner. Students devide into 2 groups: experiment group and control group. Data analysis is an independent sample test using SPSS vol. 22. Experiment group, learning is done by outing class while the control group is done in the classroom. Obtained significance of 0.029 < 0.05, indicating that there is a difference between the experimental group and the control group. Outing class has an effect on environmental awareness to elementary school pre service teacher. An in-depth study is required to modify outing class activities in enhancing environmental awareness.
Computer Supported Collaborative Writing: Does it Work among ESL Learners?
Authors: Ithnin Nur Hazirah Che , Fikray Farhanahbinti Mohamad , Razak Noor Zainab Abdul
Published: April 2018

This study examines the effectiveness of using Wiki as a platform to enhance EL learners’ writing skill in English language. In particular, the aim of this research is to examine learners’ performance in composing English language essays as well as to identify the challenges which the students faced throughout the process of writing through Wiki. This study involved the respondents from secondary school who were in Form 2 and it consists of three levels of language proficiency which the researchers have identified. Specifically, the research data is collected through writing assessments (pre-test and post-test). For pre-test and post-test, the website selected as a platform was ZOHO Wiki which is a free user friendly online server designed for collaborative writing. The data from pre-test and post-test was analysed according to the marks obtained. Particularly, the research findings showed that students positively show an encouraging improvement in their English language essays and writing skill. Besides, some   challenges on the Wiki website and technological related issues that occurred during the process of Wiki mediated writing have also been identified such as difficulties in terms of Wiki tools software, technological related problem, collaborative writing issues, and other relevant challenges related to the research topic. In addition, the pedagogical implications, limitations as well as recommendations on the future research which are relevant to the present study are discussed and elaborated. In short, collaborative learning through Wiki provides learners with an interactive platform for writing English language composition.
Analisa Kualitas Semen Melalui Pengukuran Konstanta Dielektrik Dan Resistivitas
Authors: Cahyono Bowo Eko , Misto Misto , Arivah Holili Nur
Published: April 2018

Cement is an adhesive material that is capable of tying dense ingredients into one solid unity, cement was used as construction materials. Any materials including cement has physical properties and is largely determined by the magnitude of the internal condition of the materials. This research was conducted to find out the quality of cement by using measurements of the dielectric constant and resistivity values. The materials examined in the form of 3 brands of cement mixed with sand and water. This research method using capacitive and resistive by using an oscilloscope as a voltage reader. Note that the three cement brands have the same dielectric constant value i.e. amounting to 0.30 and resistivity value of 30.00 Ωm on day 28. The relationship between the dielectric constant value against the addition of age showed a decrease, while for values of resistivity shows an improvement. Onthe measurement of the dielectric constant shows that cement A brand more quickly achieve drying compared to brand B and brand C, as for the measurements of the resistivity shows that cement brand C more quickl yachieve drying compared to cement brand A and brand B.
COTIDIANO E VIOLÊNCIA: A ESPETACULARIZAÇÃO DA VIOLÊNCIA COMO SUBSISTEMA NA SOCIEDADE DE CONSUMO DIRIGIDO/ Violence and daily life: The spectacularization of violence as a subsystem in the consumer society directed
Authors: Duarte Risaldo Lima , Nogueira Amélia Regina Batista
Published: April 2018

O cotidiano não deve ser compreendido como um sistema único, ele é formado por um conjunto de sistemas ou subsistemas como a moda, a cozinha, o automóvel, a sexualidade, o erotismo e o turismo. Portanto, a violência e o espetáculo que se faz dos atos violentos se constitui um subsistema? A partir desse questionamento, esse trabalho busca discutir a ideia de que a espetacularização da violência presente no cotidiano pode ser considerada como um desses subsistemas. Trata-se de uma discussão teórica acerca da violência estabelecida no cotidiano, em que os atos violentos são consumidos em forma de espetáculo. Os objetivos desse texto foram: compreender a espetacularização da violência como um subsistema; entender a violência como mercadoria e apresentar as condições necessárias para estabelecer essa espetacularização com um subsistema. O estudo apontou aspectos que revelam o consumo direcionado ao uso de atos violentos como uma mercadoria espetacular, capaz de definir a espetacularização da violência como um subsistema dentro da sociedade burocrática de consumo dirigido.
CANDESARTAN IN CARDIOLOGY PRACTICE
Authors: Dzhaiani N. A.
Published: April 2018

The most significant risk factor for the development of cardiovascular diseases such as myocardial infarction, ischemic heart disease, chronic heart failure, is arterial hypertension (AH). [1] AH also contributes to the development of cerebrovascular pathology (ischemic or hemorrhagic stroke, transient ischemic attack) and kidney diseases (chronic kidney disease).
A PATIENT WITH ACUTE CORONARY SYNDROME WITHOUT ST-SEGMENT ELEVATION AND CONSERVATIVE MANAGEMENT. PHARMACOLOGICAL OPTIONS TO IMPROVE PROGNOSIS
Authors: Barbarash O. L. , Kashtalap V. V.
Published: April 2018

The original article tells about the key aspects that characterize the problem of acute coronary syndrome without ST-segment elevation (ACSWSTE) in the Russian Federation: high prevalence, current approaches to risk assessment of early and long-term adverse outcomes and diagnostic challenges. Based on the data from the All-Russian Register RECORD-3, the main factors limiting the effectiveness of treatment of patients with ACSWSTE are highlighted: underestimated relevance of risk calculators (GRACE) and biological markers for myocardial necrosis by practicing physicians who manage these patients, underutilization of invasive treatment, failure to prescribe drugs that improve prognosis, including dual antiplatelet therapy in patients with conservative management. The prospects for the use of ticagrelor (Brilinta) to improve short- and long-term prognosis of the disease are estimated.
RIVAROXABAN IN LONG-TERM PREVENTION OF CARDIOVASCULAR EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME
Authors: Shalaev S. V.
Published: April 2018

In patients with acute coronary syndrome (ACS), the combination of dual antiplatelet therapy (DAT) and parenteral anticoagulants (unfractionated or low molecular weight heparin or fondaparinux) in the acute (inpatient) phase of the disease correlates with the most significant reduction in cardiovascular complications (CVC). Numerous attempts have been made to prolong the anticoagulant potential with enteral medications during long-term prevention of CVC in the outpatient setting in patients with recurrent ACS, both with vitamin K antagonists and new oral anticoagulants. J. Oldgren et al., based on the results of a metaanalysis of seven such studies, concluded that addition of an enteral anticoagulant “on top” of acetylsalicylic acid or DAT after an ACS episode is accompanied by a significant reduction in the risk of major CVC, while the hemorrhage frequency increases almost two-fold. [1]
PREVENTION OF VENOUS THROMBOEMBOLIC COMPLICATIONS IN PRIMARY CARE
Authors: Novikova N. A. , Shilova A. S.
Published: April 2018

Venous thromboembolic complications remain a widespread cause of mortality and disability in hospitalized patients both in surgery and primary care all over the world, despite the fact that medical and mechanical methods of prevention have been known for several decades.
ORAL ANTICOAGULANTS IN THE TREATMENT OF VENOUS THROMBOEMBOLIC COMPLICATIONS: FOCUS ON APIXABAN
Authors: Gilyarov M. Yu. , Konstantinova E. V.
Published: April 2018

Venous thromboembolism (VTE), comprising deep vein thrombosis and pulmonary embolism, is a common condition associated with a significant clinical and economic burden. Anticoagulant therapy is the mainstay of treatment for VTE. Current guidelines recommend the use of either low molecular weight heparins or fondaparinux overlapping with and followed by a vitamin K antagonist for the initial treatment of VTE, with the vitamin K antagonist continued when long-term anticoagulation is required. These traditional anticoagulants have practical limitations that have led to the development of direct oral anticoagulants that directly target either Factor Xa or thrombin and are administered at a fixed dose without the need for routine coagulation monitoring. The paper reviews results of the trials of apixaban application for treatment and/or long-term secondary prevention of VTE. The paper analyses effectiveness and safety of apixaban in different groups of patients, as well as features of apixaban application in every day practice.
CLINICAL VALUE OF DETERMINING GALECTIN-3 IN PATIENTS WITH CHRONIC HEART FAILURE
Authors: Gyamdzhyan K. A. , Kukes V. G. , Maksimov M. L.
Published: April 2018

Relevance:today, the task of finding new biomarkers that could help monitor the effectiveness of pharmacotherapy, ensuring early diagnosis and predicting the clinical outcome of the disease continues to be relevant.

Purpose:the purpose of the study was to assess the clinical value of determining galectin-3 in patients with chronic heart failure (CHF).

Material and methods:the study included 53 patients (women n = 31, men n = 22) with CHF II-III FC NYHA. The mean age of patients was 71 (95% CI 68.99-74.37). The group of patients with CHF II NYHA included 14 people, and the group with CHF III NYHA - 39. The median baseline level for NT-proBNP was 65.7 pmol/L, the median baseline for galectin-3 - 8.37 pmol/L.

Results:increased levels of galectin-3 correlated with reduced EF (%) (R = -0.26, p = 0.04), increased serum creatinine (r = 0.26, p = 0.04) and elevated plasma levels of NT-proBNP (r = 0.3, p = 0.02). No statistically significant relationship was obtained with other clinical indicators, such as SBP, DBP, heart rate, BMI, the 6-minute test, LVMI, LVM, glucose, TC, GFR. We obtained a moderate correlation between the plasma levels of NT-proBNP and galectin-3 (r = 0.3, p = 0.02). Reduced levels of galectin-3 after treatment were observed in 84.3% of patients.

Conclusion.Galectin-3 can be used as an additional diagnostic biomarker for CHF. The incidence of congestive heart failure (CHF) is 1–2% among the population in the developed countries reaching >10% in patients aged over 70 years. [1] Despite a significant progress in the treatment of CHF over the past decades, the mortality rate is very high reaching 60% in men and 45% in women after 5 years after the initial diagnosis. [2] Therefore, the development of new methods for the prevention and treatment of CHF is a relevant medical and social problem.
CONTINUOUS ECG MONITORING: WHAT DO CLINICAL GUIDELINES SAY
Authors: Yavelov I. S.
Published: April 2018

In clinical practice, electrocardiogram (ECG) is interpreted after registration across at least 12 leads or after completion of a multi-hour ECG monitoring (which can also be performed in 12 leads), and in real time with a simple visual observation or by automatic analysis of the individual parameters. At the same time, in real time ECG the number of leads may be different, including 12, and it does not exclude the possibility of simultaneous recording for archiving and subsequent additional analysis. The apparent advantage of ECG interpretation in real time is the possibility of a rapid response to the identified disturbances (particularly, in the event of life-threatening arrhythmias and myocardial ischemia). Retrospective analysis of a long-term ECG recording does not offer such a possibility.
CARDIOVASCULAR AND GASTROINTESTINAL COMMUNICATION: PREDICTIVE VALUE FOR COMORBID PATIENT
Authors: Vlasova T. V. , Shkarin Vl. V. , Solovieva E. V. , Romanova S. V. , Makarova T. Y.
Published: April 2018

The article provides the description of the clinical importance of comorbidity, its epidemiology, the attention is focused on the highest prevalence and prognostic significance of cardiovascular and gastrointestinal pathogenetic relations complicating the course of the cardiovascular pathology by development of erosive-ulcerative lesions of stomach and duodenum, the first manifestation of which are often life-threatening gastrointestinal bleeding. Symptomatic gastroduodenal ulcer lesions (SGUL) are described in detail including their modern definition, classification, epidemiology, clinical manifestations and diagnosis with a detailed analysis of features of pathogenesis and course of patients with cardiovascular diseases. SGUL induced by nonsteroidal anti-inflammatory drugs are analyzed including those induced by low-dose acetylsalicylic acid (NDA), risk factors for their occurrence and prevention in groups at high and moderate gastrointestinal risk are considered. The need for further scientific research of topical issues of «comorbidity» to improve diagnosis and treatment of comorbid pathology in public health practice are stressed.
Determination of Cryptosporidium spp. in Van cats by nested PCR
Authors: KILINÇ ÖZLEM ORUNÇ , YILMAZ ALI BILGIN , GÖZ YASAR , ÖZKAN CUMALI , DENIZHAN VURAL
Published: April 2018

The present study was conducted to investigate the presence of Cryptosporidium spp. agents in cats from the Turkish Van Cat Shelter at YüzüncüYıl University by a modified Ziehl-Neelsen staining method and nested PCR. Individual stool samples were obtained from 30 adult females, 30 adult males and 40 kittens – a total of 100 Van cats were analyzed in the study. A simplified formol-ether concentration method was applied to all samples. The samples were then examined microscopically by a modified Ziehl-Neelsen staining method. As a result of the staining, Cryptosporidium spp. oocysts were identified in stool samples of 3 kittens in the microscopic examination. After that, PCR and nested-PCR were conducted with suitable primers. Nested PCR identified 5 kittens (5%) as positive. As a result, it was concluded that nested PCR was a superior diagnostic method for Cryptosporidium diagnosis compared with staining methods and that infected cats could be a health hazard for other cats and individuals, since Cryptosporidium spp. agents infect via the faecal-oral route. Therefore, we believe it is necessary to raise the awareness of people in contact with cats..