bluuebunny/crossref_metadata_2025 huggingface dataset:
Amplified concern for social risk in adolescence: Development and validation of a new measure
Authors: Andrews Jack L , Foulkes Lucy , Bone Jessica , Blakemore Sarah-Jayne
Published: September 2019

In adolescence, there is a heightened propensity to take health risks such as smoking, drinking or driving too fast. Another facet of risk-taking, social risk, has largely been neglected. A social risk can be defined as any decision or action that could lead to an individual being excluded by their peers, leading to a reduction in one’s social hierarchy or loss of face; such as appearing different to one’s friends or standing up for an unpopular peer. In the current study, we developed and validated a measure of concern for health and social risk for use in individuals of 11 years and over (N=1399). Using exploratory and confirmatory factor analysis we show that concerns for health and social risks are distinct categories. Concerns for both health and social risk declined with age, challenging the commonly held stereotype that adolescents are less worried about engaging in risk behaviours, compared with adults. The rate of decline was steeper for social versus health risk behaviours, suggesting that adolescence is a period of heightened concern for social risk. We validated our measure against measures of rejection sensitivity, depression and risk-taking behaviour. Greater concern for social risk was associated with increased sensitivity to rejection and greater depressed mood, and this association was stronger for adolescents compared with adults. We conclude that social risks should be incorporated into future models of risk-taking behaviour, especially when they are pitted against health risks.
The psychology of partner choice
Authors: Martin Justin , Young Liane , McAuliffe Katherine
Published: September 2019

Partner choice captures the idea that individuals exist in a biological market of potential partners, and we can therefore choose or reject our social partners. While prior work has principally explored the functional basis of partner choice, here we focus on its mechanistic basis, motivated by a surge of recent work exploring the psychology underlying partner choice decisions. This work demonstrates that partner choice is predictably sensitive to a number of factors, including 1) a potential partner’s generosity and fairness, 2) cooperative disposition, 3) moral decision-making, and 4) intentions. We then broaden our scope, first reviewing work suggesting that, in some cases, the psychology underlying partner choice may be distinct from other responses to a partner’s behavior. We then discuss work demonstrating the sensitivity of partner choice decisions to market characteristics as well as work that illuminates the neural, ontogenetic and phylogenetic basis of partner choice. We conclude by highlighting outstanding questions and suggest directions for future research.
Understanding Culture with a Transnational Population: a Value-Sensitive Approach
Authors: Alsheri Tag , Abokhodair Norah , Olivier Patrick
Published: September 2019

It is widely acknowledged in design that culture is embodied in many aspects of an individual’s identity. Many design methods operationalize this understanding through the use of cultural markers or predefined cultural dimensions. Here, we take a first step to distil the culturally specific values of the Saudi culture. We adopt a bottom-up approach that allows for values to emerge from the data by reflecting on two studies of a transnational population: a form of identity where the choice of cultural values is conscious and deliberate. Despite their different goals, the two studies yield common overarching core cultural values. Using a value-sensitive approach, we propose a process for designers to identify culturally specific values, illustrating this in our context of interest: Saudi culture.
Evaluation of internal geometries within the Miocene Utsira Formation to establish the geological concept of observed CO2 responses on 4D seismic in the Sleipner area, North Sea
Authors: Kennett Christopher , Jackson Christopher Aiden-Lee
Published: September 2019

CO2 has been injected into the Miocene Utsira Formation at the Sleipner field in the Norwegian North Sea since October 1996. Repeat seismic surveying over the injection site in 1999, 2001, 2004 and 2006 have revealed the temporal development of the CO2 plume. However, in order to help better understand future plume development and aid in locating a new injection site the geological evolution of the Utsira Formation and its resultant stratal architecture needs further development in the greater Sleipner area. Combined used of seismic and well data show that the base of the Utsira Formation, the Middle Miocene Unconformity (MMU), is heavily deformed by soft sedimentary deformation. The source for this deformation is mass sand mobilization and injection of Skade Formation sandstones in the otherwise dominantly argillaceous sediments of the Upper Hordaland Group. Skade Formation sandstones are observed thickening in up-folded, and mounded regions of MMU, where seismic data reveal V-shaped amplitude anomalies or ‘chaotic’, noisy areas. Outside the deformed areas the Upper Hordaland Group is an otherwise flat sequence of continuous acoustic reflectors that are offset by a pervasive network of polygonal faults. Onlapping reflection terminations of lower Utsira Formation reflectors onto the deformed surface of the MMU indicate that soft sedimentary deformation occurred at a shallow depth before deposition of the Utsira Formation. Stratal elements within the sand rich (0.98 N:G) Utsira Formation include: i) south westerly dipping clinoforms, ii) erosional scours, and iii) large-scale sand waves, suggesting high depositional energy and potential erosion of (c.1 - 2.5 metre thick) shale interbeds. During deposition of the Utsira Formation differential compaction within the Upper Hordaland Group has down-folded, and rotated intra-Utsira reflectors onto underlying MMU mounded features. Løseth’s et al. (2003) and Jackson’s (2007) models for gas and fluid expulsion from the mobilized sediments during burial, leading to differential compaction, is the preferred hypothesis for this phenomenon. The result of collapsed sediments on reservoir architecture is folding, and the creation of the anticlinal internal geometries where the CO2 is injected today. CO2 reached the top of the reservoir by 1999, via a sequence of small accumulations beneath interpreted as intra-formational shale beds. It appears from this rapid ascent that shale layers are laterally discontinuous, and perhaps eroded by the high-energy depositional model inferred.
Corruption and Illicit Financial Flows in Nepal
Authors: Bhusal Tara Prasad
Published: September 2019

In recent years, considerable intellectual interest has arisen over the extent of illicit financial flows which may have development, governance or other consequences for both developed and developing countries. Illicit financial flows involve the cross-border transfer of the proceeds of corruption, trade in contraband goods, criminal activities, and tax evasion. The main objective of this article is to explore the current situation of illicit financial flows from the developing countries with special reference to south Asia and Nepal. The article also explains its causes, impact and measures to stem those flows. Although much effort and resources have been used to stem the illicit financial flows in the world, it is in increasing trend specially in case of developing world.
नेपालका सन्दर्भमा ग्रामीण विकासका निम्ति विकेन्द्रीकरण Nepalka Sandharbhama Gramin Bikaska Nimti Bikendrikaran
Authors: खड्का Khadka भबिन्द्र Jhabindra बहादुर Bahadur
Published: September 2019

विकास भनेको क्रमशः बढ्दै र सुधँ्रदै गएको भौतिक स्थिति हो । यसलाई उत्तरोत्तर प्रगति र क्रमिक परिवर्तका रूपमा पनि अथ्र्याउन सकिन्छ । नेपालको भौतिक विकास र समृद्धिका सन्दर्भमा यो अध्ययन केन्द्रित छ । यस अध्ययनमा नेपालका सन्दर्भमा ग्रामीणविकासका निम्ति विकेन्दीकरण कति आवश्यक छ भन्ने विषयमा केन्द्रित रही विषयको विश्लेषण गरिएको छ । विगतका वर्षहरूमा यस विषयमा निकै प्रयत्नहरू भएका हुन् तापनि विकेन्द्रीकरणलाई सिद्धान्ततः नस्वीकारेसम्म विकासको प्रतिफल सर्वसाधारणसम्म पुग्दो रहेनछभन्ने कुरा प्रायः सिद्ध भइसकेको छ । स्थानीय तहमा हुने र गरिने सबै खाले निर्णय निर्माण र कार्यक्रम कार्यान्वयनमा जनसहभागिता हुने भएकाले विकास गर्न सरल र सहज हुन्छ । अब आउने दिनमा ग्रामीण विकास गर्नका लागि विकेन्द्रीकरणको सिद्धान्त अवलम्बन गर्नु नेपालका सन्दर्भमा अत्यन्त आवश्यक देखिन्छ । यसले विकासमा सर्वसाधारणको पहुच बढ्ने र अपनत्व अनुभव हुने हुँदा विकासको गतिमा तीव्रता प्रदान गर्दछ । यस लेखमा सम्बन्धित क्षेत्रका जनप्रतिनिधि तथा जनसाधारणसँगको अन्तरक्रियात्मक विधिबाट सामग्री सङ्कलन गरीविषयको विश्लेषण गरिएको छ ।
Penerapan Strategi Cost Efficiency (Efisiensi Biaya) Pada PT Bank Muamalat Indonesia, Tbk. Tahun 2017
Authors: Izzah Nidaul , Rachmawan Muhammad Zakaria
Published: September 2019

This research discusses about the implementation of the cost efficiency strategy at PT Bank Muamalat Indonesia, Tbk. As for the phenomenon of the problem that the authors observe on the financial ratios report of PT Bank Muamalat Indonesia, Tbk., especially in the BOPO ratio (Operating Costs to Operating Income), it ranks fourth highest out of a total of 13 Islamic Commercial Banks in Indonesia. Based on the authors’ observation, it has implemented the cost efficiency strategy that is also carried out by banks in general. However, there are some obstacles that result in inefficient bank performance, so the BOPO ratio is still high. Therefore, PT Bank Muamalat Indonesia, Tbk. has made several solutions to overcome the obstacles faced
HEALTH EDUCATION TERHADAP PENGETAHUANIBU TENTANG PERAWATAN BAYI BERAT LAHIR RENDAH DI RUANG TERATAI RSUD DR.HARJONO PONOROGO
Authors: Wulandari Catur
Published: September 2019

Low birth weight babies (BBLR) is still a problem worldwide because it is acause of morbidity and mortality in the newborn, especially during the perinatal period.LBW care is good and true will improve the quality of life LBW so avoid the risk ofgrowth and developmental disorders and death. The purpose of the study to determine theeffect of health education on mother's knowledge about the care of Low Birth WeightBaby in Teratai Room Dr.Harjono Ponorogo Hospital.Pre-experimental research design with One Group Pretest-Posttest approach.The study was conducted 1-31 December 2018. The population is all mothers with LowBirth Weight Infants in Teratai Room Dr. Harjono Ponorogo a total of 37 people and asample of 31 people, with accidental sampling The independent variable is healtheducation and the dependent variable is knowledge. Instruments with quesionare.Statistical test using wilcoxon signed rank test with α = 0.05.The result of knowledge before health education is mostly 16 respondents(51,6%) enough and after health education mostly 18 respondents (58,1%) goodknowledge, p value 0,000 ≤ α 0,05 there is influence of health education to motherknowledge about care of Low Birth Weight Infant in Teratai room of RSUD Dr.HarjonoPonorogo.Nurses can improve the quality and quantity of health education activities inLotus room so that the knowledge of mother be good and can do care of Low BirthWeight at home.
PENGARUH JENIS PEKERJAAN DENGAN KETIDAK AKTIFAN IBU BERKUNJUNG KE POSYANDU DESA JALEN KECAMATAN BALONG KABUPATEN PONOROGO
Authors: Mustikawati Ambika Kurnia
Published: September 2019

Based on the Register Cohort weighing a toddler on November 10, 2018 atPosyandu Jalen there are 65 men mother toddler retrieved 25 (38.4%) bringing his son tothe always active and 40 posyandu (61.6%) mother toddler people not actively bring hisson to the Posyandu. A preliminary study of 10 people who are not active toddler'smother obtained work mother who brings her son off to their busy work posyandu 3(30%) as civil servants, 3 (30%) as farmers and 4 (40%) as a trader.Type of this research is quantitative approach to koresional and use the form ofcross sectional. The sample was all mother toddler who came to the village of posyanduJalen Subdistrict Balong Ponorogo in January 2019 with the inclusion criteria and aretaken using the technique of accidental sampling. The instruments used in this study usingquestionnaire. Analysis of the influence between the variable using the correlation testchi square with 0.05 significant level.The work of mothers in the village of Posyandu Jalen Subdistrict BalongPonorogo almost half of the respondents i.e. as many as 25 (38.4%) working as the IRTand as many as 20 (30.9%) working as a trader. The aktifan visit the mother of most ofthe respondents (58.5%) i.e., 38. There is the influence of the type of work with theinactivity of the mother paid a visit to the village of posyandu Jalen Subdistrict BalongPonorogo with statistical test p = 0.000. The kind of work that is most influentialWorking Moms as traders who are all as many as 20 respondents (100%) and motherworking as CIVIL SERVANTS who are all as many as 7 respondents (100%) not active inthe visit of the posyandu.Solutions carried out visits to posyandu on the schedule set by the posyandu andliveliness for a visit should arise on the mother because the toddler is a define in time isgrowing important role, will happen a whole person, due to his physical growth aspectshave first gained attention as well as conduct posyandu cadre in order to approach withentwined good cooperation.
Gambaran Kepuasan Terapi Pasien Diabetes Melitus Tipe 2 di Puskesmas Daerah Istimewa Yogyakarta
Authors: . Nur Rasdianah
Published: September 2019

Keberhasilan pengobatan diabetes melitus tidak hanya pada efikasi dan keamanan obat tetapi juga pada kepuasan terapi. Kepuasan terapi memiliki peran penting dalam pengelolaan diabetes. Penilaian kepuasan terapi secara rutin pada pasien diabetes melitus berguna bagi profesional kesehatan untuk mengidentifikasi masalah potensial yang dialami oleh pasien selama menjalani pengobatan. Penelitian ini merupakan penelitian observasional dengan metode pengambilan sampel menggunakan teknik accidental sampling. Sebanyak 123 pasien diabetes melitus tipe 2 rawat jalan direkrut dari puskesmas daerah Yogyakarta pada bulan Agustus–September tahun 2015. Instrumen penelitian berupa lembar pengambilan data dan kuesioner Diabetes Medication Satisfaction Tool (DMSAT). Data dianalisis menggunakan Chi-Square. Hasil penelitian menunjukkan bahwa tingkat kepuasan terapi pasien diabetes melitus tipe 2 berada pada kategori cukup puas sebanyak 49 subjek (39,84%), dan kategori puas sebanyak 74 subjek (60,16%). Hubungan antara kepuasan terapi dan jenis kelamin (p=0,458), usia (p=0,139), tingkat pendidikan (p=0,241), durasi penyakit (p=0,901), jumlah komorbid (p=0,130), dan riwayat diabetes (0,906) tidak signifikan (p>0,05) kecuali  ADO  (p=0,040 < 0,05). Kepuasan terapi harus lebih ditingkatkan lagi untuk memaksimalkan pengobatan pasien
Quantitative determination of glycine in pharmaceutical formulations by reaction with 2,3-dichlor-1,4-naphthoquinone reagent
Authors: Portna K. P. , Vasyuk S. O.
Published: September 2019

Glycine has been reported to be determined by different techniques including titrimetric methods, VIS spectrophotometry. Some of the proposed methods require inaccessible reagents, others – difficult in execution or offered only for substances. That is why, feasibility of developing new, simple, valid methods for the glycine quantitative determination in medical forms is not in doubt.

This paper presents a new, simple and accurate VIS spectrophotometric method for determining of glycine in pharmaceutical formulation using 2,3-dichlor-1,4-naphthoquinone as a reagent.

Pharmaceutical preparations: capsules of Doppel Herz, 0,50 g (Queisser Pharma Gmbh & Co, Germany); powder in packets Medichronalum-Darnitsa, 7,00 g (Pharmaceutical company «Darnitsa», Ukraine); tablets of Glycin («Biotiki», Russia).and Glicised («Arterium», Ukraine), 0,10 g.

Analytical balance (ABT-120-5DM); UV-VIS spectrophotometer (Specord 200); water bath (Memmert WNB 7-45).

The aliquot part (0,1200‒0,2000 g) of the glycine is put into a 25,00 ml volumetric flask, add 7,00 ml water and filled to the mark with DMF. The amount of 1,00 ml of the resulted solution is poured into a 25,00 ml volumetric flask, then treated with 2,50 ml of 1% solution of the 2,3-dichlor-1,4-naphthoquinone and mixed up. A received solution is heated up for 15 minutes on the water-bath under temperature of 95 °С, then is cooled down and filled to the mark with the DMF. Absorbance of the test solution is measured at 470 nm against the background of the compensation solution that does not contain any test solution.

Defined minimum calculated by common method is 3,20 mcg/ml.

Experimentally determined glycine optimal reaction conditions with the 2,3-dichlor-1,4-naphthoquinone as the basis for the development of spectrophotometric methods for glycine quantitative determination in the 4 drug dosage forms.

The analytical method was optimized and validated by establishing the linearity (in the range of 5,00‒8,00 mg/100 ml), the correlation coefficient (r = 1,000), precision and the accuracy.

Thus, the peculiarity of the developed method consists in it’s enhanced sensitivity in comparison with other available methods of quantitative determination. The developed method is simple and useful for routine analysis of glycine in pharmaceutical formulations and in-process quality control.
Synthesis of some new thiazolo[4,5-b]pyridin-2-ones and research of their anti-inflammatory activity
Authors: Chaban T. I.
Published: September 2019

In modern theoretical and clinical medicine inflammation problem remains one of the main.Deregulation of inflammatory processes leads to specific pathologies.There is a significant amount of drugs used to treat inflammation. But all of them have varying degrees of ulcerogenic properties. To overcome these limitations search is ongoing throughout the World to find new effective and safe anti-inflammatory agent. Therefore, of course, the synthesis of thiazolidines annelated with the pyridine cycle and the study of their anti-inflammatory properties is an interesting and relevant area.

The objective of the present work was to synthesize a series of novel thiazolo[4,5-b]pyridine-2-ones by the structural modification of the (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide for further pharmacological screening in vivo as anti-inflammatory activities.

The objects of the study were thiazolo[4,5-b]pyridines, obtained by the structural modification of the (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide. Anti-inflammatory activity was evaluated using carrageenan induced rat paw edema method in rats

In vivo studies were carried out  for anti-inflammatory activity employing the carrageenan-induced rat paw edema method. Anti-inflammatory activity was defined by measuring the paw edema volume 4 h after the carrageenan injection.The NSAID drug Ibuprofen in effective therapeutic doses were tested inparallel as an activity references. Inhibition of the inflammatory response was expressed as a percentage of the paw volume reduction. Studies of anti-inflammatory activity showed that the synthesized compounds had pronounced diuretic properties, and some of them according to activity indicators were approaching or exceeding comparative preparations.

The results of the anti-inflammatory activity of the synthesized compounds derivatives (5,7-dimethyl-2-oxo-thiazolo[4,5-b]pyridine-3-yl)-acetic acid hydrazide show the potential for the search for anti-inflammatory agents among thiazolo[4,5-b]pyridine-2-ones.
Antiinflammatory activity of 2-, 3-, 4-carboxymethylpyridinium hexafluorosilicates on carrageenan model of inflammation
Authors: Pristupa B. V. , Shyshkin I. O. , Rozhkovsky Ya. V. , Gelmboldt V. O.
Published: September 2019

In the last decade, high cariesprophylactic efficacy of ammonium hexafluorosilicates, including salts with substituted biologically active ammonium cations, has been demonstrated. Among the promising anti-caries agents are recently synthesized 2-, 3-, 4-carboxymethylpyridinium hexafluorosilicates, for whose cations anti-inflammatory activity is expected.

The aim of the work is to assess the presence of anti-inflammatory activity in the series of 2-, 3-, 4-carboxymethylpyridinium hexafluorosilicates in the experiment.

2-, 3-, 4-Carboxymethylpyridinium hexafluorosilicates (I–III, respectively) were synthesized according to the previously proposed technique, carrageenan is a commercial preparation, reference drug is a indomethacin. Experiments on the anti-inflammatory activity of hexafluorosilicates were performed on 77 white Wistar male rats weighing 174–190 g using the carrageenan model of inflammation. The inflammatory reaction was reproduced by subplantary administration of 0.1 ml of a 0.2% solution of carrageenan, the studied compounds were administered orally in doses 1/10, 1/20, 1/50 from LD50 for the compound III.

It was established that after administration of carrageenan, animals of the control group showed marked paw edema, which gradually increased and was maximal after 24 hours of observation. According to the data obtained, the indices for compounds I-III practically do not differ from those of the control group. This indicates that, despite the results of the PASS forecast and the presence of acetic acid residue, an anti-inflammatory pharmacofor, in compounds I-III, the compounds under study do not have an anti-inflammatory effect in the carrageenan model.

2-, 3-, 4-Carboxymethylpyridinium hexafluorosilicates do not show the expected anti-inflammatory activity in the carrageenan model of inflammation.
Antibacterial properties of thioridazine
Authors: Hrynchuk N. , Vrynchanu N.
Published: September 2019

The emergence and spread of antibiotic-resistant strains of microorganisms reduces the effectiveness of antibiotic therapy and requires finding solutions to problems, one of which is the study of antimicrobial properties in drugs of various pharmacological groups.

The purpose of the work was to summarize the data on the antibacterial activity of thioridazine and its derivatives to determine the feasibility and prospects of creating new antibacterial drugs on their basis.

The paper presents literature data on the effects of thioridazine on the causative agent of tuberculosis, antistaphylococcal activity, susceptibility of plasmodium and trypanosoma.

The antibacterial activity of the drug was established within in vitro studies with the determination of MIC towards gram-positive and gram-negative microorganisms, ex vivo using macrophage lines, as well as within in vivo experiments on mice.

It is established that the neuroleptic thioridazine is characterized by pronounced anti-tuberculosis activity, the mechanism of action is associated with the impact on the cell membrane of M. tuberculosis, inactivation by calmodulin and inhibition of specific NADH-dehydrogenase type II.

The literature data indicate that thioridazine is able to increase the activity of isoniazid against the strains of mycobacteria that are susceptible and resistant to its action. It has been established that resistance to thioridazine in antibiotic-resistant M. tuberculosis strains is not formed.

The drug is characterized by its ability to inhibit the growth and reproduction of both methicylin-sensitive (MSSA) and methicilin-resistant (MRSA) strains of Staphylococcus aureus, which has been proven within in vitro experiments.

The effectiveness of thioridazine has been proven within in vivo experiments in case of skin infection and sepsis caused by S. aureus. Antimicrobial effect of the drug is also observed towards to plasmodium (P. falciparum) and trypanosomes (Trypanosoma spp.).

Currently, the synthesis of thioridazine derivatives is carried out to identify compounds with a pronounced antibacterial effect. Some of the first synthesized compounds are not inferior or superior to thioridazine by the inhibitory effect.

Thus, these data suggest that drugs of different pharmacological groups, including drugs that affect the nervous system - thioridazine and its derivatives, can be a source of replenishment of the arsenal of antimicrobial drugs to control such threatening infections as tuberculosis and diseases caused by polyresistant strains of microorganisms.
Synthesis, physical-chemical and biological properties of 8-R-thioderivatives of 1-benzyltheobromine
Authors: Ivanchenko D. G. , Romanenko M. I. , Samura B. A. , Kornienko V. I.
Published: September 2019

Key way for creating new medicinal drugs is structural modification of known and existent natural compounds with high biological activity. In this aspect researchers’ attention is drawn by xanthine derivatives which appear to be antagonists of adenosine receptors, phosphodiesterase inhibitors and histone deacetylase inducers. This resulted in their widespread application in medicine to cure asthma, bronchitis and chronic obstructive pulmonary disease. In addition, xanthine derivatives are used as diuretics, analgesics, heart pacemakers, anti-inflammatory, psychotropic and renal protective agents. 

The aim of this work lies in developing unique methods to synthesize undocumented in other scientific papers 8-thioderivatives of 1-benzylthiobromine and also studying of their physical, chemical and biological properties.

Acute toxicity of synthesized compounds has been studied with the application of Kerber method. The study of diuretic activity of obtained compounds was carried out applying Berkhin method. Analgesic activity of synthesized xanthines was studied at ‘acetic acid writhing’ model. Anti-inflammatory activity was studied at ‘acute aseptic edema’ model. Antioxidant activity was studied in vitro using the method of non-enzymatic initiation of free-radical oxidation.

Heating of 1-benzyl-8-bromotheobromine with double excess of sodium sulphidenonahydrate in dimethylformamide environment results in formation of 8-thiotheobromine. Reactions of thioxanthines with halogenketones and chloroacetamide proceed smoothly with their short-time heating in aqueous alcohol environment.

By applying such computer programs as ALOGPS, DRAGON, GUSAR and ACD/Percepta Platform was established viability of further invitro and invivo research.

Accessible laboratory methods have been elaborated to synthesize 8-thiosubstituted 1-n-methylbenzyltheobromine, their structure having been proved by elemental analysis, PMR-spectroscopy and mass-spectrometry data.

Molecular and pharmacological descriptors to forecast properties of the obtained substances have been calculated, in addition to acute toxicity index.

Also the study of acute toxicity, diuretic, analgesic, anti-inflammatory and anti-oxidant activity of synthesized compounds has been carried out.

After additional research 1-benzyl-8-(2-oxo-2-phenylethylthio)theobromine can be used in medical practice as an antioxidant agent.
Mетодичні аспекти прогнозування поширення чужорідних видів на основі фітоіндикації
Authors: БУДЖАК ВАСИЛЬ ВАСИЛЬОВИЧ , ДІДУХ ЯКІВ ПЕТРОВИЧ , ЧОРНЕЙ ІЛЛЯ ІЛЛІЧ , ТОКАРЮК АЛЛА ІЛАРІОНІВНА
Published: September 2019

Проникнення інвазійних видів у природні угруповання буде успішним у тому випадку, якщо зона оптимуму більшості факторів для інвазійного виду буде накладатися (перекривати) на стресову зону цих самих факторів для угруповання, тобто потрапляти у діапазон значень так званої зони «зниженої ценотичної конкуренції». Дана гіпотеза перевірена на основі аналізу 2736 геоботанічних описів трав’яних угруповань, які належать до 26 союзів з території верхніх басейнів Прута та Сірету, у складі флори яких виявлено 106 чужорідних видів, у тому числі 5 видів-трансформерів. Проаналізовано ступінь перекриття діапазонів зон толерантності модельних видів (Erigeron annuus (L.) Desf. (вид трансформер), Cichorium intybus L. (інвазійний вид), Sisyrinchium septentrionale E. P. Bicknell (інвазійний вид) та угруповань у відсотках за відношенням до 12 провідних екофакторів (водний режим ґрунту (Hd), змінність зволоження (fH), аерованість (Ae), кислотний режим (Rc), сольовий режим (Tr (Sl)), вміст карбонатів у грунті (Ca), вміст засвоюваних форм азоту (Nt), термоклімат (терморежим) (Tm), вологість клімату (омброрежим) (Om), континентальність клімату (контрасторежим) (Kn), суворість зим (кріорежим) (Cr), освітлення (Lc)). Встановлено наявність модельних видів у складі угруповань тих союзів, де спостерігається сумарне перекриття зон толерантності екофакторів на 80-100%. Сформовано тривимірні моделі, що ілюструють залежність між часткою перекриття зони оптимуму виду, стресової зони та зони оптимуму угруповання, які можна використати для оцінки можливості проникнення інвазійних видів у природні рослинні угруповання та виявити потенційні угруповання для їх закріплення.
Pengaruh Kepatuhan Diet, Aktivitas Fisik dan Pengobatan dengan Perubahan Kadar Gula Darah pada Pasien Diabetes Mellitus Suku Rejang
Authors: Almaini Almaini , Heriyanto Hendri
Published: September 2019

Diabetes mellitus (DM) is a chronic disease characterized by blood glucose levels exceeding normal and impaired metabolism of carbohydrates, fats and proteins due to a relative or absolute deficiency of insulin hormones. This study aimed to determine the relationship between dietary compliance, physical activity, and adherence to taking medication with blood sugar levels when in patients with type 2 diabetes mellitus. This type of research was analytical with a cross-specific approach that uses a sample of 46 Rejang tribal diabetes mellitus patients who come to Curup Health Center, Prumnas Health Center and Delima Village Health Center during the period of August to October 2018 which met the criteria for inclusion and exclusion. The instruments used were food recall forms, questionnaires, medical records and glucometers. The results of the study were processed by bivariate analysis using the chi square test and multivariate analysis with logistic regression test. The results of the bivariate statistical test dietary compliance variable p = 0.001 OR = 15,343, CI = 3,327-67,636, and the medication adherence variable p = 0,035, OR = 4,038, CI 1,061-15,370. There was a significant relationship between diet compliance, adherence to taking medication with blood sugar levels when in patients with diabetes melititus Rejang tribe Rejang Lebong District. DM patients are expected to always adhere to diet, physical activity and medication treatment.
Peran Sicantik dalam Meningkatkan Kinerja Perawat di Rumah Sakit
Authors: Swedarma Eka , Dwidasmara Dwidasmara
Published: September 2019

The low ability of nurses in documenting nursing care as a result of limited human resources, too much writing format, differences in perceptions between nurses and the inability of nurses to enforce nursing diagnoses accurately will have an impact on the performance and service delivery to patients. This study aimed to fine out the nurse’s performance based on the characteristics of respondents and determine the effect of the application of the Si-Cantik application program (Electronic nursing record system) on the performance of nurses at the hospital. The research method used a one group pre-post test design approach with an intervention in the installation of an electronic nursing record system that is computer-based in the treatment room. The sampling technique used Simple random sampling with  sample of 35 nurses. Statistical analysis using Chi-square test and Wilcoxon signed rank test. The results showed that the majority of respondents (77.14%) found it easy to apply the program, most nurses (77.68%) had good performance and statistically the implementation of the electronic nursing record system had an effect on nurses' performance in providing nursing care in hospitals (p = 0.004). The application of electronic nursing records system can be applied by nurses as supporting nurses' performance in providing nursing care in hospitals and becoming a reference in the use of digital nursing as an effort to develop self-potential so that they can carry out nursing services professionally.
Keyakinan sebagai Faktor Penting dalam Kepatuhan Pengobatan TB pada Anak
Authors: Trianingsih Devi , Wanda Dessie , Waluyanti Fajar Tri
Published: September 2019

Children are one of the most vulnerable populations to the spread of tuberculosis (TB) ger, however, unfortunately the success of TB treatment in DKI Jakarta is still quite low. This study aimed to determine the factors that most influence TB child treatment adherence. The method used was descriptive analysis with cross sectional approach. The sample was determined using techniques Consecutive Sampling: Non Probability Sampling  which numbered 168 people. This study illustrated that belief variable  was the most influencing factors of TB treatment adherence in children (p value 0,001; α=0.05; OR 8,02 after controlled by long-term treatment of TB, PMO, cognitive developments stages, coping behaviour, memory, treatment regimens, communication with health care providers, social support and access to health facilities.  This study expected to be source of knowledge for nurses to provide client’s belief  and improve adherence to TB treatment in children.
Faktor – Faktor Yang Berhubungan Dengan Konsumsi Buah-Sayur Pada Remaja Di Daerah Rural-Urban, Yogyakarta
Authors: Oktavia Alfonsa Reni , Syafiq Ahmad , Setiarini Asih
Published: September 2019

Vegetable consumption of the Indonesian population is still low in the teen age group both in rural and urban areas. Consumption of fruits and vegetables in adolescents is important for preventing degenerative diseases. The aim of the study was to determine the factors associated with fruit and vegetable consumption in adolescents in rural-urban areas. This study used a cross-sectional research design in Yogyakarta with 196 rural-urban teens. The analysis used was univariate, bivariate, analysis. The results showed that teenagers in urban areas ate less vegetables. Whereas in teenagers in rural areas, they consume less fruit. There is a significant relationship between vegetable consumption in adolescents in rural areas with father's education level (p = 0.031) and self-image perception (p = 0.041), while in urban areas there is a significant relationship between vegetable consumption and self-image perception (p = 0.049) and education in adolescents (p = 0.047). Fruit consumption in adolescents in rural areas that are significantly related is the perception of body image (p = 0.016), while in adolescents in urban areas that are significantly related is monthly money (p = 0.003). Suggestions that can be given are provide health education about the importance of the benefits of vegetables and fruit.
ENHANCEMENT OF THE EFFICIENCY OF USE OF RETAIL AND METALLURGICAL SALES
Authors: Zaselskiy V.I. , Popolov D.V. , Sorokin A.V. , Osadchuk Yu.G. , Gukov S.A.
Published: September 2019

Рurpose. Expansion of the raw material base of ferrous metallurgy, a significant reduction of the environmental burden on the environment, and the reduction of areas under the sludge septic tanks.
Problem and its connection with practical tasks. The main waste of metallurgical production is sludge - disperse material, which includes a significant amount of iron oxides, manganese, calcium, which are currently either not utilized at all, or are utilized in very small quantities; sludges for their storage are formed in a dump; while their liquid part drains into the soil, while contaminating the groundwater, and the solid part after the natural drying is prone to wind erosion and pollutes the atmosphere.
The article considers the possibility of full use of sludge, which excludes their storage.
Emerging threat in antifungal resistance on superficial dermatophyte infection
Authors: Sultana Razia , Wahiduzzaman Md
Published: September 2019

Background: Dermatophytosis are most common fungul infection globally and according to WHO the prevalence is about 20-25% and does not spare people of any race or age. Over the past few years antifungal resistance has been emerged due to irrational use of antifungal drugs in cutaneous mycosis.

Objective: The aim of the study is to evaluate the efficacy of different antifungul drugs (Terbinafin. Fluconazole, Itraconazole, Griseofulvin) on superficial mycosis depending on various factors.

Methods: This prospective study was conducted among the Superficial fungul infected patients from April' 2017 to October 2017 in Khulna Medical College Hospital (KMCH) and dermatologist's private chamber in Khulna city. All the enrolled patients were put on oral Terbinafin, Fluconazole, Itraconazole and Griseofulvin. Each patient was given single antifungal drug orally. These cases were thus followed up after two months of treatment to look for persistent infection, cure or any relapse clinically.

Result: Among 194 patient 89 were given Tab. Terbinafin (250mg) where resistance cases were 20.22%. More cases (33.96%) were resistant to Cap. Fluconazol (50mg). High percentage of cases were resistant to Cap. Itraconazole (76.47%). Griseofulvin resistant cases were observed in 25.71%. Drug response is very poor (69%) in patient who had been suffering from diabetes mellitus.

Conclusion: Appropriate antifungal drugs should be chosen with strict indication, dose, duration, selection of perfect local preparation and taking laboratory facilities where necessary.

Bang Med J (Khulna) 2018; 51 : 21-24
Causative agents for diarrhoea in under 5 children in a tertiary care hospital
Authors: Pervin Mst Khashruba , Jhora Sanya Tahmina , Paul Shikha , Naher Akhtarun , Sarkar Dipika
Published: September 2019

Background: nfectious diarrhoea is a major public health problem in developing countries like Bangladesh. Bacteria and parasites are important etiological agents for diarrhoea in infants and children.

Objectives: To isolate and identify the causative organisms of diarrhoea from diarrhoeal stools in under 5 children.

Methodology: This was an observational cross sectional study carried out at Microbiology Department of Sir Salimullah Medical College, Dhaka. A total of 217 diarrhoeal patients upto 5 years age, attending Pediatric unit of Sir Salimullah Medical College and Mitford Hospital, Dhaka and Dhaka Shishu Hospital, Dhaka during the period of July 2015 to June 2016, were enrolled in the study. For isolation of enteric bacteria, diarrhoeal stools were inoculated on Mackonkey agar media and for Campylobacter spp. diarrhoeal stools were inoculated on selective Modified Campy-BAP media and nonselective Blood agar media with membrane filter. Positive culture was confirmed by Gram stain morphology and standard biochemical tests. Oocysts of Cryptosporidium were identified by Modified Ziehl Neelsen staining and other parasites were identified by wet mount preparation.

Results: Out of 217 diarrhoeal stools bacteria were isolated from 97 (44.7%) patients. Among 97 cases, Escherichia coli were detected in 51(52.58%) patients; Campylobacter spp. were detected in 23(23.71%) patients; Shigella spp. were detected in 15(15.46%) patients and Salmonella spp. were detected in 8(8.25%) patients. Microscopic finding of diarrhoeal stools were detected by pus cells with or without RBCs in 90(70.31%) samples. Cysts of Giardia intestinalis were found in 9(4.14%) samples, cysts of Entamoeba histolytica in 2(0.9%) samples, eggs of Trituris trichiura in 2(0.9%) samples and oocysts of Cryptosporidium were found in.5(2.30%) samples.

Conclusion: Escherichia coli was the most common bacteria and Giardia intestinalis was predominant parasite causing diarrhoea in under 5 children.

Bang Med J (Khulna) 2018; 51 : 25-28
ANALISIS TINGKAT KESEHATAN BANK DENGAN METODE RGEC (STUDI KASUS PADA PT.BANK MUAMALAT Tbk) PERIODE 2012-2016
Authors: Ghozali Zein , Hanifa Riri , Hendrich Mahdi
Published: September 2019

Penelitian ini bertujuan untuk mengetahui tingkat kesehatan PT.Bank Muamalat Indonesia Tbk periode 2012 sampai dengan 2016, diukur dengan menggunakan pendekatan RGEC (Risk Profile,Good Corporate Governance, Earnings dan Capital). Penilaian Kesehatan bank ini berdasarkan Peraturan Bank Indonesia Nomor 13/1/PBI/2011. Jenis Penelitian yang digunakan adalah penelitian deskriptif dengan pendekatan kuantitatif. Variabel Risk Profile diukur dengan menggunakan rasio NPL, Posisi Devisa Netto (PDN) dan LDR. Variabel dan pengukuran pada penelitian ini terdiri dari faktor Risk Profile, Faktor Good Corporate Governance, faktor Earning dan faktor Capital. Hasil analisis menunjukkan bahwa tingkat kesehatan PT.Bank Muamalat Indonesia Tbk pada periode 2012 sampai dengan 2016 dalam kategori sehat. Indikator Risk Profile dikategorikan pada posisi Low to moderate selama periode 2012-2016. Indikator GCG dikategorikan Baik selama periode penelitian. Indikator Earning PT.BMI Tbk dikategorikan Kurang Sehat selama periode 2012-2016. Dengan menggunakan indikator CAR, peneliti membuktikan bahwa PT.Bank Muamalat Tbk memiliki faktor Capital yang baik, yaitu diatas ketentuan Bank Indonesia sebesar 8%.
PENGARUH PEMBERIAN PENGUATAN TERHADAP MOTIVASI BELAJAR SISWA KELAS V SDN 018 RANTAU SIALANG KECAMATAN KUANTAN MUDIK KABUPATEN KUANSING
Authors: Citra Yulia , Syahrilfuddin Syahrilfuddin
Published: September 2019

This research is in the background by the weakness of student learning motivation in the teaching and learning process, one of which is characterized by students tend to be passive and less enthusiastic. The purpose of the study was to find out whether there was an effect of giving reinforcement to students 'learning motivation and how much influence the giving of reinforcement on students' learning motivation. The approach in this study is quantitative with the type of experimental research, the design of this study is pre-experimental. The pre-experimental design used in this study was one pretest-posttest group. The subjects in this study were 27 grade V students of SDN 018 Rantau Sialang with 8 men and 19 women. The variables in this study are the variables of giving reinforcement and student motivation. Data collection using documentation and questionnaires. Validity test using Pearson product moment formula and reliability test using Alpha formula. The analysis prerequisite test used the normality test with the Kolmogrov-Smirnov One Sample test using SPSS 17.0 for windows. Hypothesis testing uses the t test with the help of SPSS and the last effect test. The results showed that there was an effect of giving reinforcement to students' learning motivation, as evidenced by the results of the t test at a significant level of 1% and 5% namely tcount> ttable or at level 1% (7,751> 1,298) at the level of 5% (7,751> 1,674). Calculation of the effect test (effect size) obtained by ES is 3.146, this figure is included in the high category because the effect size is more than 0.8. It was concluded that giving reinforcement had an effect on the learning motivation of V grade students of SDN 018 Rantau Sialang Kecamatan Kuantan Mudik Kabupaten Kuansing with a high category
Transnacionalismo desde abajo y multiculturalismo desde arriba: perspectivas de ciudadanía para la incorporación migrante en Chicago
Authors: Cruz Lera Estefanía
Published: September 2019

The restructuring of citizenship has become a fundamental topic in the midst of contemporary debates surrounding the dynamics of immigrants. The research questions guiding this paper are: how are immigrant local dynamics reshaping citizenship? Why is the approach of immigrants and that of local governments towards citizenship so sharply contrasting? And, what are the consequences of these contrasts for immigrant incorporation? This paper presents a case study of the citizenship perspectives of Chicago’s immigrants and of the city's government, contrasting the transnational approach emerged from below with a multicultural project posed from above.
Ideas y reflexiones de Manuel Gamio acerca de los migrantes de retorno (1925-1930)
Authors: Alanís Enciso Fernando Saúl
Published: September 2019

The purpose of the present study was to analyze the central ideas developed by Manuel Gamio about return migrants in a project conducted by the Mexican scholar in 1925 and in his classic work, published in 1930. These views are the first instances of academic reflection concerning return migrants in Mexico, the influence of American society on this social group, and the social and economic consequences of their return to Mexico.
How Does the Rule of Law Impact the FDI Attraction? A Panel Study on Chinese Municipal Governments (2013-2017)
Authors: Fu Chengyu
Published: September 2019

This study focuses on the impact of the rule of law on FDI attraction in Chinese cities from 2013 to 2017. I divide nomocracy into four aspects and measure their different effects on FDI inflows. Furthermore, I present credible evidence that economic backgrounds influence the rule of law's marginal effects. My research will provide reasonable conclusions that rule of law, both general measurements, and its sub-indicators, has a significant influence on FDI inflows. In addition, their impacts are conditional on the cities’ performance in economic development.
Guerreiro Ramos, reader of Eric Voegelin: post-colonial theory and alternatives to liberal modernity.
Authors: Lynch Christian Edward Cyril
Published: September 2019

The paper aims to understand how Alberto Guerreiro Ramos (1915-1982), one of the three recognized fathers of Brazilian modern social science, assimilated Eric Voegelin’s critique of modernity during the last ten years of his career in the United States. Beside the apparent obstacle of disciplinary boundaries (more apparent than real), one of the strongest reasons for this silence lies in the fact that most of Brazilian social scientists feel uncomfortable in associating Ramos with a conservative thinker like Voegelin. Nonetheless, things are always more complicated than ideological approaches may suggest. The apparent paradox of a progressivist social scientist incorporating a conservative critic of liberal modernity must be understood by means of a careful study of how Ramos developed his intellectual sensibility during his youth; the disillusions he suffered after the political breakdown of 1964 and his reactions as an émigré to his new academic environment of the United States.
Who Follows the Generals? Polarization in Institutional Confidence in the Military
Authors: Robinson Michael
Published: September 2019

The military institution enjoys consistently high levels of public confidence, making it one of the most respected entities in American society. However, this aggregate trend conceals an underlying polarization among partisans, who arrive at different conclusions over the institutional quality of the military. What explains the divide? This analysis argues a partisan bias resulting from (1) exposure to different information about the military and (2) different cognitive biases in using that information to render an opinion on institutional quality. Using observational data on news media reporting patterns and original text-as-data processed through unsupervised machine learning techniques, I find that partisans during a key phase of the Iraq War were exposed to widely different types information on military performance. Furthermore, I find through original survey experimentation that when presented with information on negative performance by the military, partisans adopt very different sensibilities in how that information is used to evaluate it.
Experience in application of hybrid contact lenses for astigmatism correction
Authors: Khandjyan Anush , Myagkov Alexander , Guryanova Olga , Petrova Olga
Published: September 2019

The review covers the issue of hybrid contact lenses application as one of the modern contact correction methods in patients with ametropias of various genesis. Hybrid contact lenses consist of a rigid central optical part made of highly gas-permeable material and a flexible peripheral part made of hydrophilic material. These lenses combine the optical correction qualities of gas-permeable corneal lenses with the comfort and stable fit usually provided by soft contact lenses. Compared to gas-permeable corneal lenses, hybrid lenses are more comfortable; often have better centration and more stable fit on the eye. Hybrid contact lenses successfully correct both types of astigmatism: regular and irregular. This type of lenses is a good alternative method of contact correction for patients who place heavy demands in terms of the quality of vision.