bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural, functional, phylogenetic, and molecular dynamic simulation study of PEST-containing nuclear protein: An e-science view
Authors: Khan Nazeer Hussain , Shahid Muhammad , Wang Wenkang , Khatak Saadullah , Ngowi Ebenezeri Erasto , Mahmoud Salma S. , Chen Hao-Jie , Qian Lei , Qin Yangzhe , Li Tao , Zubair Muhammad , Fazry Shazrul , Wu Dong-Dong , Zhang Chun Yang , Ji Xin-Ying
Published: July 2022

PEST-containing nuclear protein (PCNP) is a short-lived novel nuclear protein. It has been well evaluated that PCNP mediates the progression of several cancers, but the exact mechanisms are still under investigation. In this study, we provided an e-science view of PCNP protein from the aspects of protein structure, interactions, and bioinformatics-based analysis related to evolutionary features as well as proteomic profile. The phylogenetic relationship results reveal that PCNP is closely related to Pan troglodytes and the Bovidae family, while being distantly related to the Muridae family. The analysis of the physicochemical properties of PCNP demonstrated that it is a thermolabile protein which is slightly acidic and hydrophilic in nature. Further, coexpression and protein-protein interaction analyses were carried out, which demonstrated that the PCNP gene was remarkably expressed with MORF4LI and RSL24D1 genes and has close interactions with TRAM1, PSMC6, SRP9, PRKRIR, UHRF2, and BMI1 proteins. Gene ontology and pathway enrichment analyses showed that PCNP has a high tendency to work in cell cycle regulation. Moreover, among the four 3D structure generating tools, I-TASSER-generated structure had the highest quality factor score. The validation analysis revealed that the I-TASSER-generated structure exhibited the best quality factor score with maximum amino acids in the favored region. In addition, molecular dynamic simulation analysis approved the stable structure of the PCNP. This is the first study that highlights the usefulness of the understanding of the structural and functional analysis of the PCNP, which lays the groundwork for further experimental studies to validate the outcome.
Inhibitory effect of Solanum xanthocarpum on the growth of KB human oral cancer cell line in vitro through ROS-induced mitochondrial pathway
Authors: Vijayalakshmi Annamalai , Anitha Venkateshwaran , Mustafa Al-Antary Tawfia M.
Published: July 2022

The aim of the present study was to investigate the effect of Solanum xanthocarpum on KB human oral cancer cells by analyzing its anti-proliferative and apoptotic properties as well as its inhibitory effect on cell adhesion. In this study, the leaves extract of S. xanthocarpum was prepared using the maceration method. Cytotoxic effect of different doses of the S. xanthocarpum extract was assessed using MTT assay. Measurements of reactive oxygen species (ROS), lipid peroxidation and antioxidant enzymes were also performed. In addition, we also studied the impacts of S. xanthocarpum on the apoptosis and mitochondrial membrane potential of KB cells. Determination of antioxidant enzymes and lipid peroxidation was performed using biochemical methods. The S. xanthocarpum showed cytotoxic activity against KB cells with IC50 (200 μg/mL). Besides, DCFH-DA staining and acridine orange/ethidium bromide staining results demonstrated that S. xanthocarpum induced the generation of ROS and apoptosis in KB cells, respectively. Based on the Rh-123 staining results, S. xanthocarpum decreased mitochondrial depolarization in KB cells. Furthermore, the S. xanthocarpum treatment contributed to increased lipid peroxidation, accompanied by reduced activities of superoxide dismutase and catalase, as well as decreased glutathione content. Taken together, these findings indicate that S. xanthocarpum extract might comprise bioactive compounds of therapeutic significance, which can inhibit the growth of KB cells.
A mini-review on quantification of atherosclerosis in hypercholesterolemic mice
Authors: Chen Hui , Howatt Deborah A. , Franklin Michael K. , Amioka Naofumi , Sawada Hisashi , Daugherty Alan , Lu Hong S.
Published: July 2022

Atherosclerosis is a leading cause of morbidity and mortality in many countries. Mice are the most frequently used animal model to study the pathogenesis and molecular mechanisms of atherosclerosis. En face analyses of the aorta and cross-sections of the aortic root are the two common modes for quantifying the severity of atherosclerosis in mice. This mini-review introduces these two methods, discusses their pros and cons, and provides suggestions to optimize the quantification of atherosclerosis, thereby enhancing rigor and reproducibility in preclinical research.
Role of circulating tumor DNA in the management of patients with non-small cell lung cancer
Authors: Jin Yi-Chen , Wu Man-Qi , Chen Ke-Zhong , Wang Jun
Published: July 2022

Circulating tumor DNA (ctDNA) is DNA fragment shed from tumor cells and can be isolated from peripheral blood. ctDNA carries genomic information of cancer and is the most widely utilized indicator in liquid biopsy. The application of ctDNA is gaining traction due to its reproducible, non-invasive, and easy-to-obtain characteristics. With the development of detection approaches, ctDNA plays an important role in the management of patients with cancers. In this review, we summarize the basic ctDNA detection measurements and review its application in early screening, prognosis evaluation after the surgery, and efficacy prediction of different therapies in non-small cell lung cancer.
Incentivos económicos para el fomento de la rehabilitación edificatoria en Portugal
Authors: Gómez-Gil Marta
Published: July 2022

El presente trabajo analiza iniciativas que contribuyen a aumentar el ritmo de la rehabilitación edificatoria en Portugal, a través de ayudas de carácter económico, con el objetivo de establecer una base que pueda llevar, en estudios posteriores, a la comparación de iniciativas entre países o incluso al estudio de la aplicabilidad de determinadas medidas al caso nacional. Para ello, se describen las características de los principales programas de apoyo en el país luso, aportando los resultados que han producido, así como sus fortalezas y puntos débiles. De esta manera, se ha podido comprobar la diversidad de los programas existentes y su capacidad para dar solución a diferentes problemáticas, con diferentes escalas y necesidades, a nivel financiero y técnico.
Vitalidad urbana y sociabilidad barrial: complejidades de una metrópolis latinoamericana
Authors: Link Felipe , Señoret Andres , Fuentes Luis , Rodríguez Sebastián
Published: July 2022

Ciertos autores argumentan que la vitalidad urbana incentiva la sociabilidad entre los habitantes. Sin embargo dicha literatura concentra sus análisis en los atributos del entorno construido, como la densidad o la diversidad de usos de suelo, sin considerar las prácticas efectivas ni la influencia de los factores sociodemográficos en la sociabilidad barrial. El presente artículo busca profundizar en esta relación, analizando indicadores identificados por la literatura como condiciones necesarias para la vitalidad urbana, contrastándolos con variables de sociabilidad barrial como el uso del barrio, la familiaridad pública, la vecindad de la red y la sociabilidad entre vecinos, y con indicadores sociodemográficos para el Área Metropolitana de Santiago de Chile. Además de encontrar una influencia importante de los factores sociodemográficos, se identifica una relación más compleja entre la vitalidad urbana y la sociabilidad barrial, lo que revela la necesidad de repensar el concepto para la realidad de las metrópolis latinoamericanas.
A Complex Dynamic Model of Autonomy Development
Authors: Borges Larissa
Published: July 2022

Over the last years, language learning has been described as a complex dynamic system, encompassing different interacting subsystems, such as autonomy. In this article, I argue that autonomy development is a complex, dynamic and fluctuating process in which a point of arrival cannot be defined, as autonomy is experienced in a nonlinear and continuous way throughout life, with moments of advances, stability and setbacks, involving the interaction between a large number of processes, elements, agents, among other subsystems. In this paper, I present the Complex Dynamic Model of Autonomy Development (CDMA). This model explains the dynamics of autonomy in learners’ language learning trajectory in light of the complexity paradigm. The model has been used in research and activities with a focus on language learning and language teacher education. It has been discussed with language majoring students, pre-service and in-service language teachers as a tool for reflection, self-awareness and self-regulation, as it enables a comprehensive view of the dynamism and complexity involved in the process of developing both learner autonomy and teacher autonomy.
Methodology for Assessing Meteorological Observation Data to Account for Wind Potential in The Design of a Wind Power Plant
Authors: Mamedova Natalia
Published: July 2022

The development of clean renewable energy sources is a strategic task to ensure the balance of energy supply to territories. When implementing a policy of reducing dependence on or abandoning fossil fuels, the use of renewable energy sources is an obvious competitive solution. And for territories remote from power supply networks, the development of renewable energy sources is generally the only alternative. Wind energy is increasingly being used to generate electricity. In this sense, accurate accounting of the influence of wind potential on the energy balance is the basis of energy-saving architecture. From a thermodynamic point of view, wind is a high-quality source of energy. Its high efficiency makes it possible in principle to convert into other types of energy. However, the wind energy flow is unstable – the performance of wind power plants is due to their extremely high sensitivity to the conditions of their location. In this situation, the reliability of the initial data on wind energy resources is a criterion of paramount importance. Therefore, the development of a methodology for evaluating data from long-term meteorological observations of wind speed and direction is of important empirical importance. To design a wind power plant, it is not enough to enter ready–made data on the value of specific power and specific wind energy in the territory into economic calculations - the data deviation is too large. It is necessary to calculate the technical potential of the wind power plant for each prospective location option. Both the approach to accounting for wind potential and the approach to scaling the data of the observation station to remote territories ensure the reliability of the initial data for the design of a wind power plant. The proposed methodology highlights all these aspects and offers an algorithm for evaluating the data of long-term ground-based meteorological observations on the territory of Russia.
메타버스와 가상부동산의 문제점과 시사점에 관한 연구
Authors:   Korea Real Estate Society, Kim Jin
Published: July 2022

Currently, Metaverse is rapidly emerging in a situation where human encounters are decreasing due to COVID-19 continuing to be non-face-to-face. This metaverse and extended, virtual world are newly coined words that combine "meta," which means virtual and transcendent, and "universe," which means the world and the universe. Another expression is translated as 'virtual universe'. Metaverse was first used in Neil Stevenson's 1992 novel "Snow Crash." This refers to a virtual world in which real life in three dimensions and legally recognized activities, such as job, finance, and learning are connected. As a higher concept of virtual reality and augmented reality, it is a system that expands reality into a digital-based virtual world so that all activities can be performed in a virtual space. Specifically, in terms of politics, economy, society, and culture as a whole, it is widely used in the sense of living type, game-type virtual world, and virtual real estate where reality and non-realization coexist. This study should first consider, the concept and definition of metaverse, which is not clearly defined, and secondly, the scope of use of metaverse and virtual property, the two-way circulation of metaverse and other platforms, and establish a sound and stable, metaverse ecosystem. For this reason, the purpose of this paper is to activate the safety of metaverse and virtual real estate and the community of users so that they can be further developed.
The Strength of Organizational Culture and Education in Motivating of Entrepreneurs During the Covid-19 Pandemic
Authors: Sungkawati Endang , Suarniati Ni Wayan
Published: July 2022

This study aims to determine the effect of organizational culture and education on the performance of entrepreneurs through motivation as a mediating variable. This research type is quantitative research, in terms of the level of explanation this research is associative research with a causal relationship, namely a causal relationship. This means that the research focuses on organizational culture and motivation as mediating variables. Respondents were 59 entrepreneurs and used path analysis for the analytical tool. The results of the study indicate that organizational culture, education, and motivation affect the performance of entrepreneurs, either partially or simultaneously. While motivation does not act as a mediating variable for the influence of organizational culture on performance and education on performance. Organizational culture gives a strong and appropriate influence on the performance of entrepreneurs.
ESCAPE ROOMS FROM A COLLABORATIVE AND INTERDISCIPLINARY PERSPECTIVE
Authors: Dorado Escribano Guadalupe
Published: July 2022

La enseñanza de lenguas extranjeras debería estar siempre unida a las nuevas tecnologías y nuevos avances que se proponen en el mundo de la educación y deberían incluir algunos retos actuales que no siempre están presentes en las clases. Los tres retos que este artículo explora son el aspecto emocional, la escasa conexión de la enseñanza de lenguas extranjeras con otras asignaturas y la competitividad entre alumnos. Como propuesta para conseguir estos objetivos, proponemos para alumnos de instituto las “escape rooms” consideradas como herramienta poderosa en educación, incorporando como nuevo elemento su elaboración junto con los profesores que imparten otras materias. Los resultados mostraron estudiantes deseosos de participar y muy concentrados en cada actividad. Pudieron revisar distintas asignaturas al mismo tiempo que utilizaban como lengua principal el inglés.
THE REPRESENTATION OF GENDER IN TURKISH AS A FOREIGN LANGUAGE (TFL) COURSEBOOKS
Authors: Nalan Kızıltan , Işıl Atlı , Senem Gürkan
Published: July 2022

Some languages are grammatically gender-bound. Spanish and French, for example, assign a gender to each and every noun while Turkish has a gender-free grammatical system. However, no language is completely genderless. The overall purpose of this study is to examine the linguistic and non-linguistic manifestation of gender in Turkish as a foreign language (TFL) coursebooks. To that end, the portrayal of women and men in three volumes of the coursebook series Yeni Hitit Yabancılar için Türkçe Ders Kitabı (The Yeni Hitit Turkish Coursebook for Foreigners) has been studied using content analysis. In this study, the coursebook series has been quantitatively analysed with respect to the visibility of female and male characters in the visuals and written context and first-place occurrences and the number of words uttered by both sexes in mixed-gender conversations. Female and male characters in the coursebook series have also been compared according to their professional roles, hobbies and interests, representation in the public and private sphere and the number and quality of descriptive adjectives. The findings have shown that although men are slightly over represented in the visuals and written content, the authors of the series seem to have achieved a balanced manifestation of female and male characters in the dialogues. However, men are represented in a wider range of professional roles than women. There is no major difference between women and men with regard to the frequency of descriptive adjectives.
Synthesis of α-(perfluoroalkylsulfonyl)propiophenones: a new set of reagents for the light-mediated perfluoroalkylation of aromatics
Authors: Castillo-Pazos Durbis J , Lasso Juan D , Li Chao-Jun
Published: July 2022

In response to the demand for late-stage perfluoroalkylation in synthetic chemistry, we report the synthesis of a series of bench-stable α-(perfluoroalkylsulfonyl)propiophenones. Their application as photocleavable reagents was tested with electron-rich aromatics under metal-free, redox- and pH-neutral conditions to enable late-stage perfluorooctylation, perfluorohexylation, and perfluorobutylation.
Synthesis of Protected Precursors of Chitin Oligosaccharides by Electrochemical Polyglycosylation of Thioglycosides
Authors: Rahman Md Azadur , Kuroda Kana , Endo Hirofumi , Sasaki Norihiko , Hamada Tomoaki , Sakai Hiraku , Nokami Toshiki
Published: July 2022

Synthesis of protected precursors of chitin oligosaccharides by electrochemical polyglycosylation of thioglycosides as a monomer is described. Oligosaccharides up to hexasaccharide were synthesized under the optimized reaction conditions. The modified method by repeating electrolysis with additional monomers enabled synthesis of oligosaccharides up to octasaccharide. Mechanism of electrochemical polyglycosylation was also discussed based on the oxidation potentials of the monomer and oligosaccharides.
CONTENT AND PRESENTATION FORM ANALYSIS OF TESTING MATERIALS IN RUSSIAN LANGUAGE FOR BILINGUAL CHILDREN
Authors: Каленкова О.Н.
Published: July 2022

Настоящая статья посвящена вопросам пересмотра и корректировки некоторых субтестов в системе сертификационного тестирования школьников-билингвов на уровень владения русским языком на основе анализа результатов последних лет.

This article is devoted to the issues of revision and adjustment of several subtests in the system of certification testing of bilingual schoolchildren for the level of proficiency in the Russian language based on the analysis of the results of recent years.
THE TRAINING SYSTEM WITH INTERACTIVE TASKS: TO THE QUESTION OF THE CONTENT
Authors: Чубарова О.Э.
Published: July 2022

Статья посвящена созданию систем интерактивных заданий на основе общедоступных платформ (онлайн-сервисов). Анализируется возможная структура подобных систем, ставится вопрос о выборе их центрального элемента – интерактивного видео либо вербального текста. Приводится описание созданной магистрантами Московского государственного лингвистического университета интерактивной панорамы в сервисе Thinglink. Рассматриваются особенности восприятия графической и вербальной составляющей мультимедийного текста. Обосновывается необходимость сохранения вербального текста как основы учебного процесса и опоры на текстовый материал как на центральный элемент при создании системы интерактивных заданий.

The article is devoted to the creation of interactive task systems based on publicly available platforms (online services). The possible structure of such systems is analyzed, the question is raised about the choice of their central element - interactive video or verbal text. The description of the interactive panorama created by undergraduates of the Moscow State Linguistic University in the Thinglink service is given. The features of perception of graphic and verbal components of multimedia text are considered. The necessity of preserving verbal text as the basis of the educational process and relying on text material as a central element in creating a system of interactive tasks is substantiated.
THE MECHANISMS OF BREACHING THE NORMS IN THE TEXTS OF NON-NATIVE AND NATIVE RUSSIAN LANGUAGE SPEAKERS
Authors: Овчинникова И.Г. , Боженкова Р.К. , Габова Н.И. , Хван С.Х.
Published: July 2022

В статье рассматривается проблема межъязыкового взаимодействия в аспекте выявления типичных отступлений от норм русского языка, обусловленных дефектами в работе речевых механизмов говорящих. На материале русскоязычных речевых продуктов (эссе) франко-англо-русских трилингвов в сопоставлении с Корпусом русских студенческих текстов (CoRST) определяется общее и специфическое в речевых нарушениях, характеризуются причины ошибок инофонов и речевых сбоев носителей русского языка.

The article deals with the problem of interlingual interaction in the aspect of identification of typical deviations from the norms of the Russian language, conditioned by the defects in speakers’ verbal mechanisms. Based on the material of Russian-language speech units (essays) of French-English-Russian trilingual speakers in comparison with the Corpus of Russian Student Texts (CoRST), the article defines common and specific features in speech errors, characterizes the reasons behind the errors by foreign Russian speakers and speech failures by native Russian speakers.
Teaching Russian to Chinese students in a non-linguistic environment on the materials about coronavirus (level b1)
Authors: Лю Ц.
Published: July 2022

Статья посвящена исследованию вопросов обучения китайских студентов русскому языку (уровень В1). В ней предлагается использовать в учебном процессе актуальные новостные материалы, освещающие проблему современной действительности – пандемию COVID-19 и борьбу с новой коронавирусной инфекцией. Актуальность исследования обусловлена тем, что начиная с 2020 г. появилось большое количество лексических изменений в русском языке в связи с необходимостью обозначения реалий и явлений, вызванных пандемией. Китайские студенты, находящиеся вне русской языковой среды (уровень B1), испытывают трудности в выражении мыслей при общении с русскими собеседниками на тему борьбы с коронавирусом. Именно поэтому в данной статье обращается внимание на совершенствование коммуникативной компетенции в процессе обучения устной русской речи с использованием не только адаптированных, но и оригинальных, аутентичных текстов из новостных материалов о коронавирусе. Рекомендуются различные образовательные технологии обучения и система практических заданий для организации процесса обучения китайских студентов устной русской речи вне русской языковой среды с использованием новостных материалов о пандемии COVID-19.

The article is focused on the study of Russian language education towards Chinese students (level B1). It suggest that relevant news materials covering the urgent problem of modern reality – the problem of the COVID-19 pandemic and the fight against the new coronavirus infection (coronavirus) be used in the educational process. The relevance of the study is due to the fact that since 2020 there have been a large number of lexical changes in the Russian language due to new realities and phenomena caused by the pandemic. Chinese students who are outside the Russian language environment will find it difficult to communication with Russian people on the topic of fighting coronaviruses, if they are not familiar with the new words and fixed expressions in advance. That is why, in this article, it was chosen as a priority educational approach - using not only adapted version of original texts, but also from news materials about the coronavirus in the process of oral Russian education, to improve the ability of communication. Various educational teaching technologies and a series of practical tasks system are recommended for organizing the process of teaching Chinese students oral Russian outside the Russian language environment using news materials about the COVID-19 pandemic.
Study on the influence of laser radiation in the plaque compared with 0.2% chlorhexidine – microbiological and microscopic analysis
Authors:   Disciplina de Reabilitare Orală şi Urgenţe în Medicina Dentară, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Mocuţa Daliana , Todea Carmen ,   Disciplina de Reabilitare Orală şi Urgenţe în Medicina Dentară, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Lazea Andreea ,   Disciplina de Pedodonţie, Facultatea de Medicină Dentară, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Hogea Elena ,   Disciplina de Microbiologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie„Victor Babeş“, Timişoara, România, Muntean Cornelia ,   Facultatea de Chimie Industrială şi Ingineria Mediului, Universitatea Politehnica, Timişoara, România
Published: July 2022

Objectives. The aim of this study was to evaluate de antimicrobian effect of laser radiation and chlorhexidine 0.2% treatment for reducing the number of pathogenic oral microorganisms, especially Streptococcus mutans, adjacent orthodontic brackets. Materials and methods. The suspension of microorganisms were obtained from patients orthodontic braces wearers. The probes were inoculated with this suspension and after that were exposed to decontamination methods represented by Erbium laser using two type of parameters: 80 mj - 15 Hz and 80 mj - 8 Hz, light emitting-diode (LED) 660 nm, surgery diode and 0.2% clorhexidine. After treatment, were harvesting probes around brackets and then were incubated aerobically at 37°C. To confirm the bactericid effect of treatment, it was adopted the colony forming units method. The Microsoft Excel program, one-way ANOVA and Tukey-Kramer test were used for statistical processing. Results. According to colony forming unit method the best bactericide effect was observed for the erbium laser group, following by surgery diode group comparatively with negative control group. Following one-way ANOVA analysis it can be remarked the significance difference from groups in terms of values resulted by application of different experimental treatments. Conclusions. The present study prove the highest efficiency of Er:YAG laser radiation on newly colony forming around orthodontic brackets decontamination.
Perception of dental laser treatment for pediatric patients
Authors:   Disciplina de Reabilitare orală şi urgenţe medicale, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Todea Carmen , Lazea Andreea ,   Discipina de Pedodonţie, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România, Mocuţă Daliana ,   Disciplina de Reabilitare orală şi urgenţe medicale, Universitatea de Medicină şi Farmacie „Victor Babeş“, Timişoara, România
Published: July 2022

Objectives. To evaluate the dental anxiety level and the degree of acceptance of laser assisted pedodontic treatments from the children part. Methods. Forty pediatric dental patients presented in the Department of Pedodontics, University of Medicine and Pharmacy „Victor Babes“, Timisoara, were evaluated using the Wong-Baker pain rating scale, which was administered postoperatory to all patients, to assess their level of laser therapy acceptance. Results. Wong-Baker faces pain rating scale (WBFPS) has good validity and high specificity; generally it’s easy for children to use, easy to compare and has good feasibility. Laser treatment has been accepted and tolerated by pediatric patients for its ability to reduce or eliminate pain. Around 65% of the total sample showed an excellent acceptance of laser dental treatment. Conclusions. Laser technology has a wide application in pediatric dentistry, and dental laser treatments are very well accepted and tolerated among children.
A técnica de prona segura: cuidados com pacientes em decúbito prona
Authors: Kuse Elisandra Alves , Rocha Alisson Ferreira da , Conceição Gabrielle Felisberto , Taschetto Luciane , Cembranel Priscila
Published: July 2022

Objetivo: Descrever a participação da enfermagem frente aos cuidados para a realização e manutenção da posição de prona em pacientes com Síndrome do Desconforto Respiratório Agudo. Metodologia: Realizou-se uma revisão de literatura científica, por meio de uma revisão bibliográfica integrativa, na obtenção de uma quantidade de informações, através da base de dados das plataformas científicas digitais (EBSCO, Biblioteca Virtual em Saúde e Scientific Electronic Library), livros, artigos científicos e monografia. Resultado: Observou-se os aspectos metodológicos e a similaridade entre os resultados encontrados, buscando respostas para os resultados diferentes ou conflitantes nos estudos e apresentado em forma de resumo sinóptico. Conclusão: A posição prona se caracteriza como um recurso terapêutico a ser aplicada em pacientes com essa síndrome, na obtenção da melhora das trocas gasosas, executada pela equipe de enfermagem capacitada.
MENAKAR PELAYANAN SATUAN TUGAS LAYANAN SERTIFIKAT HALAL DAERAH PROVINSI JAWA BARAT TAHUN 2021
Authors: Susanti Ati
Published: July 2022

Undang-Undang Jaminan Produk Halal yang ditetapkan pemerintah Tahun 2014 merupakan landasan hukum pelaksanaan jaminan produk halal di Indonesia. Undang undang tersebut menjadi dasar terbentuknya Badan Penyelenggara Jaminan Produk Halal. Sebagai realisasi pelayanan, dibentuk Satuan Tugas Layanan Sertifikat Halal yang berfungsi melayani Sertifikasi Halal di daerah. Artikel ini bertujuan untuk menganalisis hambatan dan tantangan pelayanan sertifikasi halal di Provinsi Jawa Barat. Penulis menggunakan data primer. Metode yang digunakan adalah deskriptif kualitatif. Hasil penelitian menunjukkan bahwa masyarakat telah memiliki kesadaran atas arti penting sertifikat halal, memahami hambatan dan tantangan prosedur pelayanan pada Satuan Tugas Layanan sertifikat Halal Provinsi sebagai keniscayaan dari sebuah proses pelayanan yang efektif dan efisien. Pelaku usaha memiliki persepsi positif atas waktu, biaya, SOP pelayanan dan penggunaan teknologi, yang difahami sebagai bagian penting dan modern untuk mencapai pelayanan cepat dan mudah. Adapun elemen penting pelayanan berupa keramahan, kemudahan dan respon pelayanan mendapat nilai yang cukup tinggi. Fungsi pelayanan konsultasi, mendapat penilaian yang baik, karena dianggap mampu memotivasi pelaku usaha untuk memiliki sertifikat halal,  memahami arti penting sertifikasi halal, berperilaku disiplin dan taat aturan sebagai proses yang harus ditaati untuk mendapatkan pengakuan produk yang halal,  dan lebih memahami nilai dari  halal dan thoyib.
Optical Linear Polarization Study toward Czernik 3 Open Cluster at Different Spatial Scales
Authors: Uppal Namita , Ganesh Shashikiran , Bisht D.
Published: July 2022

We present the optical linear polarization observation of stars toward the core of the Czernik 3 cluster in the Sloan i band. The data were obtained using the EMPOL instrument on the 1.2 m telescope at Mount Abu Observatory. We study the dust distribution toward this cluster by combining the results from our polarization observations with the data from Gaia EDR3, WISE, and the H i, 12CO surveys. In addition, we use the polarimetric data of previously studied clusters within 15° of Czernik 3 to understand the large-scale dust distribution. The observational results of Czernik 3 show a large range in the degree of polarization, indicating that the dust is not uniformly distributed over the plane of the sky, even on a small scale. The distance to Czernik 3 is constrained to 3.6 ± 0.8 kpc using the member stars in the core region identified from Gaia EDR3 astrometry. This makes it one of the most distant clusters observed for optical polarization so far. The variation of observed degree of polarization and extinction toward this cluster direction suggests the presence of at least two dust layers along this line of sight at distances of ∼1 and ∼3.4 kpc. There is an indication of the presence of dust in the center of the cluster as seen from an increase in the degree of polarization and WISE W4 flux. The large-scale distribution of dust reveals the presence of a region of low dust content between the Local Arm and the Perseus arm.
SDSS-IV MaNGA: Cannibalism Caught in the Act—On the Frequency of Occurrence of Multiple Cores in Brightest Cluster Galaxies
Authors: Hsu Yun-Hsin , Lin Yen-Ting , Huang Song , Nelson Dylan , Rodriguez-Gomez Vicente , Lai Hsuan-Ting , Greene Jenny , Leauthaud Alexie , Aragón-Salamanca Alfonso , Bundy Kevin , Emsellem Eric , Merrifield Michael , More Surhud , Okabe Nobuhiro , Rong Yu , Brownstein Joel R. , Lane Richard R. , Pan Kaike , Schneider Donald P.
Published: July 2022

Although it is generally accepted that massive galaxies form in a two-phased fashion, beginning with a rapid mass buildup through intense starburst activities followed by primarily dry mergers that mainly deposit stellar mass at outskirts, the late time stellar mass growth of brightest cluster galaxies (BCGs), the most massive galaxies in the universe, is still not well understood. Several independent measurements have indicated a slower mass growth rate than predictions from theoretical models. We attempt to resolve the discrepancy by measuring the frequency of BCGs with multiple cores, which serve as a proxy of the merger rates in the central region and facilitate a more direct comparison with theoretical predictions. Using 79 BCGs at z = 0.06–0.15 with integral field spectroscopic data from the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) project, we obtain a multiple-core fraction of 0.11 ± 0.04 at z ≈ 0.1 within an 18 kpc radius from the center, which is comparable to the value of 0.08 ± 0.04 derived from mock observations of 218 simulated BCGs from the cosmological hydrodynamical simulation IllustrisTNG. We find that most cores that appear close to the BCGs from imaging data turn out to be physically associated systems. Anchoring on the similarity in the multiple-core frequency between the MaNGA and IllustrisTNG, we discuss the mass growth rate of BCGs over the past 4.5 Gyr.
What It Takes to Measure Reionization with Fast Radio Bursts
Authors: Heimersheim Stefan , Sartorio Nina S. , Fialkov Anastasia , Lorimer Duncan R.
Published: July 2022

Fast Radio Bursts (FRBs) are extragalactic radio transients that exhibit a distance-dependent dispersion of their signal, and thus can be used as cosmological probes. In this article we, for the first time, apply a model-independent approach to measure reionization from synthetic FRB data assuming these signals are detected beyond redshift 5. This method allows us to constrain the full shape of the reionization history as well as the CMB optical depth τ while avoiding the problems of commonly used model-based techniques. A total of 100 localized FRBs, originating from redshifts 5–15, could constrain (at 68% confidence level) the CMB optical depth to within 11%, and the midpoint of reionization to 4%, surpassing current state-of-the-art CMB bounds and quasar limits. Owing to the higher numbers of expected FRBs at lower redshifts, the τ constraints are asymmetric (+14%, −7%), providing a much stronger lower limit. Finally, we show that the independent constraints on reionization from FRBs will improve limits on other cosmological parameters, such as the amplitude of the power spectrum of primordial fluctuations.
Trends in Silicates in the β Pictoris Disk
Authors: Lu Cicero X. , Chen Christine H. , Sargent B. A. , Watson Dan M. , Lisse Carey M. , Green Joel D. , Sitko Michael L. , Mittal Tushar , Lebouteiller V. , Sloan G. C. , Rebollido Isabel , Hines Dean C. , Girard Julien H. , Werner Michael W. , Stapelfeldt Karl R. , Wu Winston , Worthen Kadin
Published: July 2022

While β Pic is known to host silicates in ring-like structures, whether the properties of these silicate dust vary with stellocentric distance remains an open question. We re-analyze the β Pictoris debris disk spectrum from the Spitzer Infrared Spectrograph (IRS) and a new Infrared Telescope Facility Spectrograph and Imager spectrum to investigate trends in Fe/Mg ratio, shape, and crystallinity in grains as a function of wavelength, a proxy for stellocentric distance. By analyzing a re-calibrated and re-extracted spectrum, we identify a new 18 μm forsterite emission feature and recover a 23 μm forsterite emission feature with a substantially larger line-to-continuum ratio than previously reported. We find that these prominent spectral features are primarily produced by small submicron-sized grains, which are continuously generated and replenished from planetesimal collisions in the disk and can elucidate their parent bodies’ composition. We discover three trends about these small grains: as stellocentric distance increases, (1) small silicate grains become more crystalline (less amorphous), (2) they become more irregular in shape, and (3) for crystalline silicate grains, the Fe/Mg ratio decreases. Applying these trends to β Pic’s planetary architecture, we find that the dust population exterior to the orbits of β Pic b and c differs substantially in crystallinity and shape. We also find a tentative 3–5 μm dust excess due to spatially unresolved hot dust emission close to the star. From our findings, we infer that the surfaces of large planetesimals are more Fe-rich and collisionally processed closer to the star but more Fe-poor and primordial farther from the star.
Thomson Scattering above Solar Active Regions and an Ad Hoc Polarization Correction Method for the Emissive Corona
Authors: Schad Thomas A. , Jaeggli Sarah A. , Dima Gabriel I.
Published: July 2022

Thomson-scattered photospheric light is the dominant constituent of the lower solar corona’s spectral continuum viewed off-limb at optical wavelengths. Known as the K-corona, it is also linearly polarized. We investigate the possibility of using the a priori polarized characteristics of the K-corona, together with polarized emission lines, to measure and correct instrument-induced polarized crosstalk. First we derive the Stokes parameters of the Thomson scattering of unpolarized light in an irreducible spherical tensor formalism. This allows forward synthesis of the Thomson-scattered signal for the more complex scenario that includes symmetry-breaking features in the incident radiation field, which could limit the accuracy of our proposed technique. For this, we make use of an advanced 3D radiative magnetohydrodynamic coronal model. Together with synthesized polarized signals in the Fe xiii 10746 Å emission line, we find that an ad hoc correction of telescope- and instrument-induced polarization crosstalk is possible under the assumption of a nondepolarizing optical system.
Evidence for Parametric Decay Instability in the Lower Solar Atmosphere
Authors: Hahn Michael , Fu Xiangrong , Savin Daniel Wolf
Published: July 2022

We find evidence for the first observation of the parametric decay instability (PDI) in the lower solar atmosphere. In particular, we find that the power spectrum of density fluctuations near the solar transition region resembles the power spectrum of the velocity fluctuations but with the frequency axis scaled up by about a factor of 2. These results are from an analysis of the Si iv lines observed by the Interface Region Imaging Spectrometer in the transition region of a polar coronal hole. We also find that the density fluctuations have radial velocity of about 75 km s−1 and that the velocity fluctuations are much faster with an estimated speed of 250 km s−1, as is expected for sound waves and Alfvén waves, respectively, in the transition region. Theoretical calculations show that this frequency relationship is consistent with those expected from PDI for the plasma conditions of the observed region. These measurements suggest an interaction between sound waves and Alfvén waves in the transition region, which is evidence for the parametric decay instability.
The Physical Properties of Star-forming Galaxies with Strong [O iii] Lines at z = 3.25
Authors: Wen Run , An Fangxia , Zheng Xian Zhong , Shi Dong Dong , Qin Jianbo , Gonzalez Valentino , Bian Fuyan , Xu Haiguang , Pan Zhizheng , Tan Qing-Hua , Liu Wenhao , Fang Min , Ren Jian , Zhang Yu Heng , Qiao Man , Liu Shuang
Published: July 2022

We present an analysis of physical properties of 34 [O iii] emission-line galaxies (ELGs) at z = 3.254 ± 0.029 in the Extended Chandra Deep Field South (ECDFS). These ELGs are selected from deep narrow H2S(1) and broad K

s
imaging of 383 arcmin2 obtained with CFHT/WIRCam. We construct spectral energy distributions (SEDs) from U to K

s
to derive the physical properties of ELGs. These [O iii] ELGs are identified as starburst galaxies with strong [O iii] lines of L
OIII
∼ 1042.6–1044.2 erg s−1 and have stellar masses of M
* ∼ 109.0–1010.6
M
⊙ and star formation rates of ∼10–210 M
⊙ yr−1. Our results show that 24% of our sample galaxies are dusty with A

V
> 1 mag and EW([O iii])rest ∼ 70–500 Å, which are often missed in optically selected [O iii] ELG samples. Their rest-frame UV and optical morphologies from HST/ACS and HST/WFC3 deep imaging reveal that these [O iii] ELGs are mostly multiple-component systems (likely mergers) or compact. And 20% of them are nearly invisible in the rest-frame UV owing to heavy dust attenuation. Interestingly, we find that our sample ELGs reside in an overdensity consisting of two components: one southeast (SE) with an overdensity factor of δ
gal ∼ 41 over a volume of 133 cMpc3, and the other northwest (NW) with δ
gal ∼ 38 over a volume of 103 cMpc3. The two overdense substructures are expected to be virialized at z = 0 with a total mass of ∼ 1.1 × 1015
M
⊙ and ∼ 4.8 × 1014
M
⊙ and probably merge into a Coma-like galaxy cluster.
Systematic Review of Cardiovascular Manifestations in COVID-19 and Management Consideration
Authors: Pratistha Fernanda Savitri Mega , Maliawan Rani Paramitha Iswari , Wirawan Hendy , Gunadhi I.G.N. Putra
Published: July 2022

Introduction: Coronavirus disease 2019 (COVID-19) is a health problem that is still engulfing the world that contributes to the high mortality rate globally. Death arises from the severity of the disease due to complications in important organs such as the heart. The purpose of this study was to systematically review the manifestations of cardiovascular disease in COVID-19 patients and their management in terms of published articles.
Method: This research is a systematic review research. The research was conducted using the PRISMA method. Article searches are carried out by online publications throughPubMed, Science Direct and Google Scholarthat meet the inclusion and exclusion criteria. The population is articles about the manifestations of cardiovascular disease in COVID-19 patients and their management between 2011 and 2021. Inclusion criteria are studies that examine the manifestations of cardiovascular disease in COVID-19 patients and their management using primary data in the form of cohort research designs, in English and full text available. The exclusion criteria were a case study, review study and used secondary data. The data were analyzed by univariate analysis by calculating the frequency and percentage.
Result: The results show that several manifestations of cardiovascular disease in COVID-19 patients include cardiac injury, heart failure, myocardial infarction, myocarditis, cardiomegaly and others.Complications of these diseases occur with or without comorbidities and the risk increases with comorbid cardiovascular disease. The management of COVID-19 patients is basically done with antiviral agents, reducing symptoms and protecting important organs such as the heart.
Conclusion: In the treatment of COVID-19 patients with cardiovascular complications, the use of antiviral agents such as lopinavir or ritonavir should be used with caution because: may interact with cardiovascular drugs. Mechanical circulation support is suggested and the use of extracorporeal membrane oxygenation (ECMO) can also be performed totreat cardiovascular complications in COVID-19 patients.
Keywords: COVID-19, cardiovascular, manifestation, management, systematic review.
Self-management Effectiveness on the Quality of Life of Type 2 Diabetes Mellitus Patients during the COVID-19 Pandemic in Aceh, Indonesia
Authors: Fithria Fithria , Husna Cut , Ahyana Ahyana , Nurhidayah Irfanita , Jannah Syarifah Rauzatul
Published: July 2022

Background: Type 2 Diabetes Mellitus (DM) is a comorbid factor with a double risk of increased morbidity and mortality due to COVID-19. Therefore, diabetic patients need to prevent COVID-19 seriously. However, they also need to regularly check their condition in health care services, such as hospitals and community health centers, making them more vulnerable to Covid-19 infection. One factor playing a significant role in controlling diabetes is self-management. Self-management activities can increase independence in caring for and controlling the health of diabetic patients. Then, it also enhances self-efficacy to improve the quality of life among diabetic patients. This study aimed to examine the effect of self-management on quality of life among patients with type 2 DM.
Method: Fifty patients with type 2 DM consented to participate in the study. The patients were assigned to either the control group receiving standard care or the experimental group receiving standard care and self-management. The program was constructed using Kanfer’s three self-management steps, including self-monitoring, self-assessment, and self-reinforcement. The effect of the intervention was measured by the WHO Quality of Life Questionnaire (WHOQOL-BREF), consisting of 26 statement items on a 5-point Likert scale and a self-management intervention evaluation checklist. Data were analyzed using an independent sample t-test.
Results: The results showed a significant difference between the pre and post-intervention in the experimental group's quality of life of type 2 DM patients (p=0.000 and α = 0.01).
Conclusion: This study found that self-management effectively increases the quality of life among diabetic patients. The health care providers, especially the nurses interested in community and family health nursing, are suggested to improve the self-management of diabetic patients to prevent complications and improve the quality of life of the patients.
L’État des LGBTI
Authors: Prauthois Lus , Biland Émilie
Published: July 2022

Cet article articule la sociologie de l’État et de l’action publique et la sociologie des minorités sexuelles et de genre afin d’analyser l’évolution des conditions sociales et politiques de ces dernières dans un contexte de reconnaissance, partielle et controversée, de leurs droits. Les États occidentaux ont construit leur pouvoir sur les populations à partir d’identifications et de classements fondés sur le sexe et la sexualité. Au cours des dernières décennies, le déclin du répertoire fondé sur la répression, l’exclusion et l’invisibilisation au profit des normes d’égalité des droits et de lutte contre les discriminations conduit à ce que la citoyenneté des personnes LGBTI soit désormais prise en tension entre indifférence et exigence de dévoilement, entre discrimination et reconnaissance. Leurs expériences des services publics – en tant que personnels comme en tant que publics – varient fortement selon les contextes organisationnels et relationnels, ainsi que selon leurs positions au sein des différents rapports sociaux de domination, ce qui fragilise leur statut social.
Distinctions légales ou discriminations ?
Authors: Frémont Camille , Prauthois Lus
Published: July 2022

S’appuyant sur deux enquêtes menées en France entre 2011 et 2020, cet article montre que les parents homo/bisexuels sont confrontés à plusieurs dimensions de l’hétéronormativité lorsqu’ils interagissent avec les services publics. Leur traitement différentiel par les agents des services publics peut venir d’une distinction légale ou d’une discrimination dans la prise en charge. Ces personnes homo/bisexuelles deviennent parents en marge des services publics français médicaux et de l’adoption qui consacrent l’hétérosexualité reproductive. Elles font face à la présomption d’hétérosexualité qui transforme les premiers contacts avec les services publics de l’enfance en coming-out . Elles négocient des arrangements au quotidien avec la CAF, la crèche, l’école, etc. Les interprétations et réactions des parents varient en fonction de leur trajectoire sexuelle et sociale, leurs ressources socio-économiques, leur statut juridique et des marges de manœuvre offertes par chaque service public.