bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabonomic analysis of the haemolymph reveals the dual effects of dietary selenium supplementations on growth of silkwormBombyx mori
Authors: Zhang R. , Peng L.L. , Zhu H.T. , Jiang L. , Thakur K. , Tang S.M. , Hu F. , Wei Z.J.
Published: November 2022

Selenium (Se) is a vital micronutrient for the growth and development of organisms; however, its deficiency and toxicity pose worldwide challenges. Herein, we investigated the absorption, accumulation effect, and distribution of Se in silkworms, and tested the effect of Se feeding on the antioxidant indexes of silkworm haemolymph. Results showed that low concentrations of Se (50 μM and 100 μM) significantly increased the enzyme activities of catalase, glutathione peroxidase, glutathione S-transferase and superoxide dismutase in the silkworm haemolymph compared to control and 200 μM group. In addition, metabonomic analysis could reveal the metabolic changes in silkworm haemolymph after treatment with different concentrations (50 μM, and 200 μM) of Se. Compared to un-treatment group, the amount of 90 metabolites in both of 50 μM and the 200 μM Se-treated groups displayed significant differences, with 50 up-regulated and 40 down-regulated in 50 μM group, 36 up-regulated and 54 down-regulated in 200 μM group, respectively. The main different metabolites were amino acids, carbohydrates, lipids, nucleotide metabolites and their derivatives. These results suggest that Se could affect the carbohydrate metabolism in silkworms. The difference in metabolites was subject to different changes under different concentrations of Se and consequently altered their metabolic functions to meet the required energy demands under the Se toxic stress conditions.
Uniqueness results for a mixed $ p $-Laplacian boundary value problem involving fractional derivatives and integrals with respect to a power function
Authors: Alsaedi Ahmed , Alghanmi Madeaha , Ahmad Bashir , Alharbi Boshra
Published: November 2022

This paper is concerned with a mixed $ p $-Laplacian boundary value problem involving right-sided and left-sided fractional derivatives and left-sided integral operators with respect to a power function. We prove the uniqueness of positive solutions for the given problem for the cases $ 1 < p \le 2 $ and $ p > 2 $ by applying an efficient novel approach together with the Banach contraction mapping principle. Estimates for Green's functions appearing in the solution of the problem at hand are also presented. Examples are given to illustrate the obtained results.
A fishery predator-prey model with anti-predator behavior and complex dynamics induced by weighted fishing strategies
Authors: Tian Yuan , Gao Yan , Sun Kaibiao
Published: November 2022

In this work, a fishery predator-prey model with anti-predator behavior is presented according to the anti-predator phenomenon in nature. On the basis of this model, a capture model guided by a discontinuous weighted fishing strategy is established. For the continuous model, it analyzes how anti-predator behavior affects system dynamics. On this basis, it discusses the complex dynamics (order-$ m $ periodic solution ($ m = 1, 2 $)) induced by a weighted fishing strategy. Besides, in order to find the capture strategy that maximizes the economic profit in the fishing process, this paper constructs an optimization problem based on the periodic solution of the system. Finally, all of the results of this study have been verified numerically in MATLAB simulation.
Aeroponic systems design: considerations and challenges
Authors: Min Albert , Nguyen Nam , Howatt Liam , Tavares Marlowe , Seo Jaho
Published: November 2022

Controlled Environment Agriculture (CEA) holds promise as a way to intensify current agricultural production systems while limiting pressures on land, water, and energy resources. However, its use has not yet been widely adopted, in part because the engineering design considerations and associated challenges are not well known. This is even more apparent for aeroponics, where the additional cost and complexities in controlling atomization have yet to establish an advantage in scale over simpler hydroponic systems To shed light on these considerations and challenges, an instrumented aeroponic system was prototyped with the goal of creating a quantitative model of growth for various species of leafy greens. As the first consideration, pressure swirl atomizers were paired with a diaphragm-type pressure tank to supply the necessary pressures needed for effective atomization. Secondly, nutrient solution was mixed on-demand from Reverse Osmosis (RO) water and concentrated nutrient stock then pumped into the pressure tank using a positive displacement pump. A bamboo-based substrate that allowed both germination and extended vegetative growth was supported on a stainless steel mesh and PVC frame acting as a grow tray. Finally, a camera microservice platform was developed to quantify plant growth using a computer vision pixel-based segmentation method.
Comparison between Pre and Posttreatment Inclination of Maxillary Incisors in Adults
Authors: Assi Samar Bou , Macari Anthony , Hanna Antoine , Aybout Josephine , Salameh Ziad
Published: November 2022

Objective:

The objective of the study is to evaluate the orthodontic treatment effect on maxillary incisors’ inclination relative to facial and growth axes in adult subjects.

Materials and Methods:

Hundred consecutive nongrowing orthodontic patients with an average age of 26.24 ± 9.29 years were selected, and their T1 (initial) and T2 (final) lateral cephalograms were digitized. Cephalometric maxillary incisors’ (I) inclination was measured to SN, PP, NA, NBa, and true horizontal (H). Facial and growth axes’ inclinations were measured relative to NBa and H. Associations were tested using Chi-square tests for categorical data. Paired sample t-tests and Pearson's correlation were computed for continuous data.

Results:

Maxillary incisors’ inclination, MP/SN, and ANB angle did not show statistically significant differences between T1 and T2, while mandibular incisors’ inclination and interincisal angle increased significantly (P = 0.01 and P = 0.02, respectively). Facial and growth axes increased at T2 but changes were not statistically significant among the two groups. At T1, correlations between maxillary incisors’ inclination and facial/growth axes were not statistically significant. Similarly, correlations between MP/SN and ANB angles on the one hand and facial/growth axes on the another hand were not statistically significant. At T2, I/PP correlated significantly with facial axis (FA)/NBa (r = 0.308; P = 0.002) and with FA/H (r = 0.268; P = 0.007). Similarly, I/SN and I/NBa correlated significantly with FA/NBa (r = 0.399; P < 0.0001 and r = 0.422; P < 0.0001 correspondingly) and with FA/H (r = 0.305; P = 0.002 and r = 0.325; P = 0.001 correspondingly). Statistically significant negative correlations existed between MP/SN angle and facial/growth axes at T2 (r values ranging −0.704 to −0.409 at P < 0.0001).

Conclusions:

While there was no correlation between I and facial/growth axes at pretreatment, significant and higher correlations existed at the end of the orthodontic treatment. This association reflects the connection between the corrected posttreatment position of maxillary incisors relative to the corresponding vertical pattern. Therefore, orthodontists should evaluate the position of the maxillary incisors to FA and may consider it in their treatment objectives.
Efficacy of Bioceramic and Calcium Hydroxide-Based Root Canal Sealers against Pathogenic Endodontic Biofilms
Authors: Suwartini Tien , Santoso Jessica , Widyarman Armelia Sari , Ratnasari Dina
Published: November 2022

Background:

Complete eradication of root canal pathogens cannot be predictably achieved by chemomechanical preparation and root canal disinfection. Therefore, an obturation material that has superior antimicrobial activity and sealing ability is required to inactivate residual microbes and prevent them from reentering the root canal system. Recently developed bioceramic root canal sealers are hydraulic cement which form calcium hydroxide during the hydration process. Like calcium hydroxide sealers, they exert an antimicrobial effect by releasing hydroxyl ions and increasing the pH.

Objective:

The objective of this study was to evaluate and compare the antimicrobial activity of a calcium hydroxide-based sealer and two bioceramic sealers against Porphyromonas gingivalis, Enterococcus faecalis, and Candida albicans biofilms.

Materials and Methods:

The sealers were dissolved in sterile saline to obtain supernatants. Biofilm formation assays, colony counting, and real-time polymerase chain reaction (PCR) were performed to evaluate the antimicrobial activity of each supernatant. The data were analyzed using one-way analysis of variance.

Results:

All sealers exerted effects against all three microbial biofilms. The biofilm formation assays showed that the bioceramic sealers were more effective against P. gingivalis and E. faecalis biofilms. In contrast, colony counting and real-time PCR showed that the calcium hydroxide sealer was significantly more effective than the bioceramic sealers. All tests showed that the calcium hydroxide sealer was more effective against C. albicans, with the colony count and real-time PCR results showing statistically significant differences.

Conclusion:

The calcium hydroxide-based sealer was more effective than the bioceramic sealers in eradicating pathogenic root canal biofilms.
Non-Surgical Ciliated Cyst of the Maxilla – An Unconventional Variant
Authors: D’Souza Zaneta Ivy , Sattar Shumail , Padhye Mukul , Desai Rajiv S.
Published: November 2022

The term surgical ciliated cyst of the maxilla is a designation for cysts of the maxillary sinus conventionally associated with surgery and trauma. Surgical ciliated cysts with a noncontributory history of surgery or trauma can pose a diagnostic challenge. We report an interesting case of ciliated cyst of the maxilla in a 54-year-old male patient. The present case provides a plausible explanation for the occurrence of ciliated cyst of the maxilla lacking history of surgery or trauma.
Mandibular Teeth as Predictors in Forensic Age Estimation: A Cone-Beam Computed Tomography-Based Pulp Volume Regression Study
Authors: Rathore Akshay , Puri Nidhi , Singh Balwinder , Kaur Kirandeep , Singh Bikramjeet , Singh Shivangi
Published: November 2022

Background:

Age estimation is integral to science of forensic odontology and plays an important role in human identification. Pulp volume estimation using cone-beam computed tomography (CBCT) to derive age can be very useful as it is noninvasive and can be applied on individuals of all ages.

Aims and Objectives:

The study aimed to estimate the chronological age-based pulp and tooth volume (PTV) ratios in adults from Uttar Pradesh, India, using CBCT and voxel counting dental software.

Materials and Methods:

Thirty-six CBCT scans were allocated into three Groups, I, II, and III (12 in each group) randomly to study the pulp volume of lateral incisor, canine, and first premolar, respectively. PTV was calculated by image segmentation method using Xelis Dental software. A correlation between chronological age with PTV was established using derived regression equations.

Statistical Analysis:

All the data were subjected to statistical analysis using Statistical Package for Social Sciences version 16.0.

Results:

Estimated age and standard error were determined. Standard errors of estimates were 11.24 years (LI), 7.78 years (C), 9.89 years (PM) group, lowest being for canines. The estimated age was compared with the chronological age. The difference between the chronological age and the estimated age by the derived equation for the present study was statistically nonsignificant (P = 1.00).

Conclusions:

The results of the study show the feasibility of calculation of PTV ratios on CBCT to estimate the age for the set population with canine as the best predictor of age for the present study population.
Evaluation of Dentin Remineralization with Zinc Oxide and Calcium Fluoride Nanoparticles – An In vitro Study
Authors: Ahalya P. , Uloopi KS , Vinay C , RojaRamya Kakarla Sri , Alla RamaKrishna , RangaRaju P
Published: November 2022

Background:

Partially demineralized dentin is remineralizable when mineral ions are made available in the near vicinity. Nanoparticles (NPs) have wide applications in remineralization process. Zinc promotes remineralization and has a synergistic effect when combined with fluoride. Hence, zinc oxide and calcium fluoride NPs were considered for dentin remineralization.

Aim:

The aim of this study was to evaluate the remineralizing ability of zinc oxide and calcium fluoride NPs on demineralized dentin individually and in combined form.

Settings and Design:

This was an in vitro study.

Materials and Methods:

Forty-eight dentin disks were prepared from the crowns of 12 extracted human molars and were allocated into four groups of 12 each, i.e., Group I – nano zinc oxide (nZnO), Group II – nano calcium fluoride (nCaF2), Group III – combined group (nZnO + nCaF2), and Group IV – artificial saliva (AS, control group). The specimens were demineralized with 37% phosphoric acid and placed in the respective remineralizing solutions for 24 h and 1 month. Calcium (Ca) and phosphorous (P) uptake was measured using energy-dispersive X-ray spectrometry, and structural changes were analyzed using scanning electron microscopy (SEM).

Statistical Analysis:

One-way analysis of variance, Student’s t-test, and post hoc Tukey’s test were used for statistical analysis.

Results:

At 1-month interval, all the groups showed an increase in Ca/P ratio, with highest being the combined group (4.24), followed by nCaF2 (3.30), nZnO (1.71), and AS (1.31) groups, and these differences were statistically significant (P = 0.000). On SEM analysis of dentinal samples at 1 month, depositions were evident in intertubular regions, wherein the highest deposits were observed in the nZnO group, followed by nZnO + nCaF2 and nCaF2 groups.

Conclusion:

Dentin samples subjected to remineralization with aqueous solutions of nZnO and nCaF2 showed an increase in calcium and phosphorous uptake and also dense granular depositions were evident in intertubular regions of dentin.
Microbiota of Dental Abscess and their Susceptibility to Empirical Antibiotic Therapy
Authors: Judith M Jemima , Aswath Nalini , Padmavathy Kesavaram
Published: November 2022

Context:

Resistant pathogens to purulent odontogenic infections have evolved due to misuse of antibiotics. Hence, it is important to use a suitable antibacterial agent.

Aim:

This study aimed to identify the common bacterial species causing odontogenic infections and to determine their antibiotic susceptibility profile to amoxicillin, amoxicillin and clavulanic acid, azithromycin, and linezolid.

Settings and Design:

This was an in vitro cross-sectional study.

Material and Methods:

Fifty pus samples from odontogenic abscess were cultured and antibiotic susceptibility tests were performed as per the standard microbiological procedures.

Statistical Analysis Used:

Binomial test and Pearson's Chi-square test were used for statistical analysis.

Results:

Out of the 50 samples cultured, 30 samples showed growth. The distribution of growth among the 30 samples was Gram-positive cocci (n = 23, 67.65%) and Gram-negative bacilli (n = 11, 32.35%). Gram-positive isolates that were grown were Enterococcus faecalis (38.24%) followed by Staphylococcus aureus (29.41%) and Gram-negative bacilli that were isolated were Klebsiella pneumoniae (14.71%), Pseudomonas aeruginosa (8.82%), Escherichia coli (5.88%), and Enterobacter (2.94%). Enterococcus isolates were highly susceptible to amoxicillin (76.92%). An increase in the zone of inhibition to amoxicillin–clavulanic acid was appreciated more for Staphylococcus (50%) than Enterococcus (30.76%). Enterococcus and Staphylococcus showed high susceptibility of 92.31% and 90% to linezolid, respectively. E. coli and Enterobacter were 100% susceptible to amoxicillin. All the Gram-negative bacteria except for P. aeruginosa were 100% highly susceptible to amoxicillin–clavulanic acid.

Conclusions:

Culture-guided antibiotic prescriptions are necessary to prevent the emergence of antibiotic-resistant bacteria.
Vitamin D Levels and Antenatal Complications in Pregnant Nigerian Igbo Women
Authors: Brian-D Adinma Joseph Ifeanyi , Ahaneku Joseph Eberendu , Adinma Echendu Dolly , Ugboaja Joseph Odilichukwu , Oguaka Victor Nwabunwanne , Adinma-Obiajulu Nneoma Dolores , Edet Mark Matthew
Published: November 2022

Background:

Serum levels of Vitamin D have been linked to some complications in pregnancy such as diabetes mellitus and premature rupture of membranes (PROM). While some studies suggest inverse relationship between serum Vitamin D levels and poor pregnancy outcomes, others report a J-shaped (curvilinear) or U-shaped relationship.

Objective:

The objective of the study is to determine the relationship between serum Vitamin D and some selected pregnancy complications among pregnant Nigerian Igbo women.

Subjects and Methods:

A prospective, cross-sectional study conducted on 256 consecutive consenting antenatal women in Anambra state, Southeastern Nigeria. Maternal blood obtained was assayed for 25 hydroxyvitamin D3 using high-pressure liquid chromatography. A pro forma was used to elicit information with respect to the biosocial characteristics of the subjects. Data obtained were analyzed using SPSS version 23, and the relationship between Vitamin D levels and antenatal complications was determined using Chi-square at P < 0.05 at 95% confidence interval being considered statistically significant.

Results:

The overall results showed that no participant had hypovitaminosis D. It also showed that there is maximum safe limit for serum Vitamin D beyond which the prevalence of hypertensive disorders/preeclampsia, preterm labor, and PROM rises. However, higher serum Vitamin D appears to be protective against clinical and laboratory-diagnosed malaria and malaria parasitemia. The study showed an inverse relationship between the degree of malaria parasitemia and serum Vitamin D levels.

Conclusion:

Despite the importance of Vitamin D in both skeletal and extra-skeletal health, there appears to be a safe upper limit. Therefore, Vitamin D supplementation should be reserved for proven cases of hypovitaminosis in pregnancy, especially in our locality where there is abundance of sunshine and low prevalence of hypovitaminosis D.
AN ANALYSIS OF SENTENCE STRUCTURE ERRORS IN ESSAY WRITINGS COMMITTED BY SOPHOMORES AT CAN THO UNIVERSITY, VIETNAM
Authors: Sang Nguyen Thai Hoai , Thu Nguyen Au Minh , Chi Nguyen Ngoc Lan , Luan Nguyen Hoai
Published: November 2022

This study investigates the common sentence structure errors and the source of those errors, focusing on the four types of sentences such as simple, compound, complex, and compound-complex. The data source for this study was collected from 80 writings composed by EFL second-year students. Simultaneously, the researchers designed an interview to explore the causes of errors, from which some resolutions were proposed. The findings revealed that there were seven (7) types of errors in terms of sentence structure: (1) Dangling Modifier, (2) Squinting Modifier, (3) Illogical Sentence, (4) Fragmented Sentence, (5) Run-on Sentence, (6) Inappropriate Coordinating Conjunction, and (7) Inversion of Subject-Verb. Those errors were caused by mother tongue influence, teaching approaches and materials, lack of grammatical knowledge and others. This research contributes to the discipline of linguistics by giving out several possible solutions that can help learners to prevent in their compositions.
 

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TAIWAN’S BILINGUAL NATION POLICY 2030: CONCERNED ISSUES AND SUGGESTIONS / 2030年國家雙語政策之重要問題與建議
Authors: Ngangbam Shantikumar Meetei
Published: November 2022

Since the inception of the new “Bilingual Nation Policy 2030” by the Ministry of Education, Taiwan, it has raised debates and concerns among people. Opinions of scholars and laymen on the new bilingual nation policy issues have been published. But so far, no local or international research papers have been published on how the people of Taiwan perceived it. The present quantitative research investigates the perceptions of people on issues such as if the policy is necessary for every Taiwanese, if the policy will neglect the local languages, if the policy can be achieved by 2030, if enough English teaching hours can be added, if enough budget can be invested, if enough trained teachers can be hired, if non-English major teachers can teach both in English and Mandarin medium by 2030, and what challenges the policy might face on its path. For this purpose, the researcher distributed a self-designed questionnaire including seven questions in which, 171 participants took part. Main findings: 55% of participants think the new policy is necessary for everyone, while 14% of them think the policy will neglect the local languages. However, only 11% of participants believe the policy can be achieved by 2030. 22% and 11% of participants respectively think Taiwan government can add enough English teaching hours and invest enough money. While 14% of participants think Taiwan government can hire enough trained teachers, and 77% of them think the policy will face many challenges like insufficient budget, lack of trained teachers and lack of equipment.

自從教育部提出“2030年雙語國家”政策以來，人們對此話題的辯論和關注程度突然升高。針對新的雙語政策，不論來自專家或是民間，各界已經發表了他們對這議題的意見。針對島內民眾對政策的觀感如何，直到目前為止，國內外還沒有學術論文的發表。本文採用量化研究，調查一般民眾對雙語政策的觀感，例如：該政策是否人人都需要它?會不會排擠母語？能不能在2030年達成雙語國家的目標?能不能增加足夠的英語教學時數? 能不能挹注充裕的經費？訓練有素的教師足夠嗎? 不是英語本科的老師們，能不能在2030年之前，同時具備母語與外語的授課能力？在施行的過程當中，可能會發生的什麼問題或挑戰?研究的目的，經由筆者親身設計的問卷，一共七題，由171名受訪者填寫完畢。主要發現如下：（一）有55%的受訪者認人人需要雙語政策，其中也有14%的受訪者也認為它會排擠母語。（二）只有11%受訪者相信該政策可能於2030年達成目標。（三）分別有22%與11%受訪者認為政府可能增加足夠的英語教學時數，與挹注充足的經費。（四）雖然有14%的受訪者認為政府可能聘用足夠的訓練有素的老師們，也有77%的受訪者認為該政策的實施將會面臨預算不足、缺乏培訓的教師，設備不足等諸多挑戰。

 

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CONTRASTIVE ANALYSIS OF ENGLISH, RUSSIAN, AND HEBREW COLOR IDIOMS
Authors: Tali Kigel
Published: November 2022

The metaphorical acquisition is a necessary element of L2 acquisition for intercultural communication. English and Russian color idioms were the subjects of numerous studies but the contrastive study of color idioms in these three languages and the investigation of Hebrew color idioms are new in the linguistics of color. The work is a summary of the project ”Contrastive Analysis of English, Russian, and Hebrew Color Idioms” consisting of eight articles that conducted contrastive quantitative and qualitative analyses about 2500 (1,100 English, 800 Russian, and 600 Hebrew) idioms with basic color terms in addition of gold and silver idioms. In the framework of the lingua-cultural approach, have been used a set of linguistic methods such as component, qualitative, statistical, contrastive, and cultural-linguistic analysis. The work covered such issues as equivalents, unique metaphors, and idioms with both primary and secondary basic color terms. The article analyzed the associative chains of meanings, the key symbolic meanings, and the 20-21st century color idioms. Special attention was paid to such lexical-semantic features of color idioms such as antonymy, synonymy, variability, and ethnic color idioms. To convey a variety of concepts, a unified systematized table of three parts with wide and flexible classification was created: Nature, Human activity, and Mental, Moral, and Ethic Issues. The results reveal a big number of equivalent color idioms and a significant number of unique color idioms contributing to enriching and widening the lingua-cultural picture of the world and related to the nature, religion, and culture of trilingual speaking communities.
 

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Integrated Management of Knee Osteoarthritis Associated Hypertension with Naturopathy and Yoga: A Case Report
Authors: Singh Poonam
Published: November 2022

Osteoarthritis of the Knees (OA Knees) also known as degenerative arthritis or degenerative joint disease is a group of mechanical abnormalities involving the degradation of joints, including articular cartilage and subchondral bone. Associated comorbid conditions such as hypertension increase the symptoms. Allopathic drugs taken to relieve the symptoms have their own side effects. The aim of treatment with naturopathy, yoga, and diet therapy is the reduction of symptoms and an increase in functional activities of patients with osteoarthritis of the knees. Naturopathy and therapeutic yogic exercises reduce pain, improve the strength of the joints, and support muscles and ligaments which provides good flexibility of the joints, and increases the range of motion. Diet plays a major role to prevent and control degeneration. A Vitamin D-rich diet helps to regenerate the joint wear and prevents worsening of the knee symptoms. Osteoarthritis may lead to early disability condition which needs to be managed as soon as possible. Osteoarthritic management requires a holistic approach.
A Book Review on Vastipradeepam
Authors: Sankar R. Abhiram , A Dr Binitha
Published: November 2022

Ayurveda was side lined in the beginning of twentieth century due to the popularity and easy access to modern healthcare facilities as well as lack of enough promptness to popularize traditional health care systems. Sri C.Krishnan Vaidyan Panavally tried to make Ayurveda more popular and practical based on the principles of classical text books, through his clinical practices and books. One such notable work by the author is Vastipradeepam, a practical handbook, written in Malayalam published by C K Raghavan Vaidyan, CKV hospital, Panavally, who is the son of author. First edition of the book was published in 1933 and the second edition was published in the year 1988. This book contains a total of 109 pages and priced at Rs 100.
Book Review on Sirassekadi Vidhi
Authors: C K Aswathi , P P Jigeesh
Published: November 2022

The book sirassekadi vidhi is one of the ancient books on treatment procedures of Ayurveda written by Puthiyedath Raman Menon, who was born in 1877 and passed away in 1965. The book attempts to authentically document the practicality of certain therapies that are very popular in Kerala but not described in any of Samhita. The reputed and mostly accepted five types of Keraliya kriyakrama viz Takradhara, Pizhichil (Kayaseka), Pindasweda, Annalepa and Thalapothichil(Sirolepa) have been explained here. In light of the basic theories of Ayurveda, their explanation and scientific analysis of their applications are carried out here from the author's personal observation and experiences
Panchakarma Excerpts From Chikitsa Sangraha : A Book Review
Authors: K Amrithalatha , P P Jigeesh
Published: November 2022

Historically, Panchakarma had a pivotal role in treating patients of Kerala through the contributions of ancient physicians and their role in reforming Panchakarma to its current form is invaluable. Most of them couldn’t document their experiences as the social context was unfavourable at that time and the methods of treatment varied in different localities. There were scarcely any undertakings for giving them a unified form. Chikitsa sangraham is one of the few works that documented the treatment methods of that era and led to the consolidation of at least some of the regional changes in practicing the Panchakarma procedures.
A Comprehensive Study on Diabetic Foot Ulcer & its Management
Authors: Sharma Puneet
Published: November 2022

A devastating side effect of diabetes, diabetic foot exacerbates the patient's health and has a big socioeconomic impact. The current review aims to describe the pathogenetic mechanisms and causes of diabetic foot while concentrating on its management as a significant health concern. Along with good foot care, raising doctors' awareness and, consequently, their capacity to recognize the "foot at risk" may lower the likelihood of amputation by preventing diabetic foot ulcers.
A Review of Ayurvedic Approach in Convalescent Care
Authors: Shankar K Aabha , Shobhana M.C.
Published: November 2022

Introduction: Most of the diseases come up or get worsened with the results of staggering health condition of its survivors. It was happened in case of Covid pandemic too. It definitely had a deleterious impact on human health and economy. This certainly hint towards the need to implement a health promotion strategy during the period of convalescence. Convalescence is the period of recuperation of health after a serious illness or injury or weakness. The care given during this period are meant to improve immunity, body strength and vitality in a systematic manner by providing gradual nourishment and also to prevent further occurrence of the disease. Materials And Methods: A comprehensive literature search related to convalescent care and description related to basic principles of Ayurveda using all available Ayurvedic compendium, research papers, editorials and review papers from various databases were thoroughly screened, compiled, analyzed and presented in a systematic manner. Results And Discussion: Health is depended up on Bala. Convalescent care in Ayurveda comprises the practices that enhance Bala and Vyadhikshamatva and improve the quality of life after an illness/weakness, gradually bringing back to normalcy. In Ayurveda, the intention of convalescent care is to bring back Dhatusamya which was deranged by a disease or due to intense treatment Bheshajakshapita. Such a care is essential during some physiological conditions like Garbha kaala and Soothika kaala also.
Role of Music as a Therapeutic Measure in Women’s Health
Authors: Sivanandan Anagha
Published: November 2022

Background: Music is such an art form that conveys emotions and perceptions even without using a language. The research activities focusing on the effects of art forms on health and well-being has been evidently increasing over the past two decades. Music therapy is a widely accepted and popular form for improving health through arts. Studies have shown that women being more sensitive and sentimental can be influenced more easily by music. Materials and Methods: Review of relevant literature from modern medical science, Ayurvedic classics, text books of Indian Musicology, previous research works, articles published in peer reviewed journals and other genuine sources of internet. Results: Music plays a significant role in improving the health and wellbeing of a female both in preventive and therapeutic aspects. Discussion: Music being the product of Akasha and Vayu Mahabhuta is capable of controlling the bodily Vata Dosha. Ayurveda consider music as a means to tackle Pitta Dosha mainly. Previous research works have shown the effect of Indian classical music on gastric and allied secretions in digestive system where there is a major role for Pitta Dosha. The coordinated activity of Hypothalamo- Pituitary- Ovarian Axis (HPO Axis) is responsible for normal menstrual and reproductive mechanism in females where Vata and Pitta are having the main roles. So music can play an appreciable role in maintaining the normal functions in HPO axis.
Use of Agada Preparation in the Current Scenario- A Review Article
Authors: Sharma Sukriti , Singh Jaram , Kaur Dr.Kulwinder , Kumar Sanjeev
Published: November 2022

Background: In current scenario, maximum diseases are caused due to idiosyncratic etiology. Agada Tantra is one of the eight branches of Ayurveda which focusses on Viruddhaahara (Incompatible food), Gara Visha (Concocted poison) and Dushivisha (Denatured/Latent Poison), conditions and their treatments. There are different types of Agada yogas that are mentioned in the Vishachikitsa granthas which possess antitoxin properties, antioxidant activities can be very useful in such disease condition. In today’s era we need complete Nirvishikarana (Detoxification) because many of the diseases are caused due to cumulative, concocted, and incompatible dietary habits. So, Agada yogas need to be evaluated and given in these conditions. Aim: To evaluate the effect of Agada Yogas for their capabilities to be adopted in the diversified field of toxicology and in current scenario. Materials & Methods: Reviewed from various text books, databases, websites, and relevant journals. Results & Conclusion: Different types of Agada Yogas mentioned in Vishchikitsa Granthas,some of them are Bilwadi Agada, Mahagada, Dushivishari Agada, Dashanga Agada and Sanjivana Agada. From various types of studies, books, and relevant journals we got to know that these Agada Yogas possess antitoxic properties and was very effective in elimination of poisons from the body. In current scenario, there are many diseases that are happen due to different types of preservatives, artificial poisons we are using in our current day to day lives. These Agada Yogas are the mixture of antitoxic medications act as an immunomodulatory, antioxidants and some of them possess hepatoprotective action also. The Ushna (hot potency), Teekshna(sharp) and vyavayi (rapid spreading) qualities of Agada Yogas aid in the eradication of various poisons from the body. These Yogas are more effective due to its Vishaghna ingredients and Prabhav.
Clinical Significance of Marma (Vital Points in Body) - A Review
Authors: Sharma Prahalad Sahai , Sharma Girdhar Gopal
Published: November 2022

The unique principle of Ayurveda is Marma Sharira. The Veda also makes mention of Marma (vital points in body). Aside from serving as anatomical landmarks, Marma are also the places where the Tridosha (basic elements of body) and its various forms, Prana, Ojasa or Soma, and Tejasa or Agni (vital elements of the body), are present. There are several disorders that come from harm to these Marma. Samhitas provide a clear definition of these illnesses' ensuing signs and symptoms. Any lesion to these areas has the potential to cause death, excruciating pain, incapacity, loss of function, and loss of sensation. Therefore, it has been stated in the scriptures that even when doing procedures, these crucial places should not be damaged and should be left intact. According to recent studies, stimulating the Marma points close by can aid to reduce pain in Marma points that are inflamed or uncomfortable. The therapeutic advantages of Marma Therapy in treating a range of physical and mental illnesses have been recorded in several research and textbooks. The goal of this work is to give an Ayurvedic-based conceptual understanding of Marma.
Complexidade, genericidade e especificidade em edifícios
Authors: Nóbrega Lívia , Amorim Luiz , Koch Daniel
Published: November 2022

Este artigo discute a interação entre leiautes espaciais efêmeros e perenes que, embora observáveis em diversos tipos edilícios, são particularmente evidentes em espaços expositivos, e propõe três modelos descritivos – complexo, genérico e específico – capazes de capturar e relacionar suas possibilidades máximas, mínimas e intermédias de desempenho das funções genéricas de ocupação e movimento. Para tal, utiliza a Bienal de São Paulo como objeto empírico, expressão que designa um conjunto de exposições e um edifício, cuja configuração espacial é simultaneamente descrita como complexa e genérica, e que, desde 1957, é reconfigurado a cada dois anos para sediar o evento – composto por exposições de arte moderna e contemporânea de grande especificidade. A análise de nove casos de leiautes de exposições Bienais e do leiaute de seu edifício no ano correspondente permitiu elaborar e testar tais modelos e sintetizar os resultados por meio de escalas que relacionam os três sistemas e suas sequências de distribuição. Estes modelos e sequências caracterizam a propriedade de mediação espacial da arquitetura (Nóbrega, 2022) e podem suportar a descrição e análise da interação entre leiautes superpostos e o desempenho de suas funções genéricas em edifícios de outros tipos e usos.
Nem só em Superquardras viverás no Plano Piloto:
Authors: Pires Lucas Gabriela , Campos Gurgel Ana Paula , De Almeida Furtado Isadora , Accioly Lima Pillar
Published: November 2022

O objetivo desse artigo é discutir a morfologia da escala residencial unifamiliar nas quadras 700 sul do Plano Piloto de Brasília, tomando como aparato teórico metodológico a Sintaxe Espacial. Foram analisados os projetos originais, tanto na escala edilícia quanto na urbana, a partir de pesquisa nas fontes primárias disponíveis no Arquivo Público do Distrito Federal. A tipologia habitacional geminada popular, embora não estivesse presente no projeto original de Lucio Costa, logo foi inserida à época da construção à oeste da via W3 sul, com vistas a solucionar a demanda por habitação para servidores antes mesmo da inauguração da capital. As VGA’s dos projetos originais demonstram que critérios de proteção à intimidade e separação entre patrões e empregados são replicados. A inserção desse modo de morar tradicional cria uma dicotomia com o modelo originalmente proposto das Superquadras, especialmente no que tange à preservação patrimonial, visto que a legislação pouco fez para evitar ou fiscalizar as mudanças das casas geminadas.
Espaços-tipo e movimento
Authors: Monteiro Julia , Amorim Luiz Manuel do Eirado , Borba do Nascimento Cristiano Felipe
Published: November 2022

As edificações podem ser entendidas como artefatos culturais que produzem e reproduzem lógicas sociais de ocupação e de movimento por meio das funções genéricas do espaço. A partir dessa premissa, tem-se por objetivo identificar os efeitos sobre as possibilidades de movimento que são gerados por alterações nos padrões de permeabilidade espacial em edifícios. A análise é realizada a partir dos conceitos de espaço-tipo e de tipos de movimento — fully closed / fully open, como definidos por Bill Hillier — nos edifícios dos museus das Minas e do Metal e do Memorial Minas Gerais Vale, projetos de mudança de uso de exemplares originalmente concebidos para abrigar secretarias do Estado de Minas Gerais.
verdadeiro, o bom e o belo
Authors: Rosa Borges de Holanda Frederico
Published: November 2022

Três dimensões estão envolvidas nos termos “verdadeiro”, “bom” e “belo”: respectivamente, Ciência, Ética e Estética. Afirmações científicas podem ser avaliadas como verdadeiras ou falsas, segundo a evidência; têm credibilidade universal e superam o “aqui” e o “agora”. “Bom” e “belo” – ou seu oposto: “mau” e “feio” – são outra coisa: eles concernem valores de julgamento dependentes de tempo e espaço. Mudamos a chave: verificação ou refutação não são mais pertinentes, as coisas são apreciadas (ou não) a depender de valores históricos e culturais, de acordo com os quais elas não são consideradas verdadeiras ou falsas, mas boas ou más, belas ou feias. A confusão entre essas instâncias implica uma abordagem ingênua da configuração arquitetônica: opções são erradamente tomadas como “falsas” ou “erradas” quando, na verdade, são ética ou esteticamente determinadas. Nesses casos, códigos arquitetônicos, pelos quais gostamos ou não os lugares, ficam implícitos, mas deviam tornar-se explícitos; assume-se erradamente que “problemas” (simples incompetência à parte) resultam do desconhecimento da “verdade”, porém sua identificação como problemática (ou não) é função de valores afeitos a modos de ter, agir, pensar e sentir – o habitus de Pierre Bourdieu – que posiciona os sujeitos na escala social.
Acessibilidade metropolitana e produção territorial: um anel viário para o mercado imobiliário na Região Metropolitana de Natal/RN
Authors: Costa do Nascimento Rodrigo , Ferreira Dantas George Alexandre , Bezerra Faria Trigueiro Edja
Published: November 2022

Este artigo visa compreender como a recente formação de um anel viário em parte da Região Metropolitana de Natal (Rio Grande do Norte) impactou na dinâmica imobiliária, em área de consolidação do bairro de Lagoa Nova (Natal/RN) e de expansão do município de São Gonçalo do Amarante. Na primeira, em constante transformação urbana, preços de imóveis –  principalmente apartamentos – tem se elevado conforme dilatação do núcleo global ou conjunto de vias mais acessíveis da cidade. A outra, com características de espraiamento urbano, tem sofrido, nos últimos anos a gradual elevação de preços fundiários, após ampliação das conexões viárias que dão acesso ao novo aeroporto internacional Aluízio Alves. Através desses dois recortes passam eixos que se somam a um anel viário metropolitano influente nas tendências de fluxos e movimentos intraurbanos entre os dois municípios, em especial após conclusão do acesso sul para o novo aeroporto. Como método usa-se a Sintaxe do Espaço para aferir, mediante medidas de integração (centralidade) e atravessamento (choice), como os níveis de acessibilidade metropolitana da malha urbana dão respostas ao processo de precificação – para mais ou para menos – se apresentando como instrumento de análise da valorização imobiliária.
Evaluasi Kebijakan Dana Desa untuk Penanggulangan Kemiskinan dan Peningkatan Infrastruktur Pelayanan Dasar Air Minum serta Sanitasi Kabupaten/Kota di Indonesia
Authors: Chehafudin Muhamad , Wibawa Samodra , Wibowo Soesilo
Published: November 2022

This study aims to analyze the effect of the Village Fund on poverty alleviation and improvement of basic infrastructure services for drinking water and sanitation in districts and cities in Indonesia. The need for evaluation of the Village Fund policy is a consequence of the implementation of fiscal decentralization to villages based on Law no. 6/2014. This policy has implications for an increase in transfer funds to villages of more than IDR 329 trillion cumulatively. Theoretically, fiscal decentralization to villages should improve public services and accelerate poverty reduction through local preferences matching and more efficient allocations. This research was a quantitative study using path analysis to test the hypotheses. Data were obtained from BPS and the Ministry of Finance for all districts/cities receiving Village Fund. The results show that The Village Fund had a significant effect on poverty reduc-tion nationally, although its contribution was very small, and the effect was not significant in districts/cities with low fiscal capacity. The Village Funds had an effect on increasing drinking water but not significant, on the other hand, it had a significant effect on districts/cities with medium or low fiscal capacity with low poverty rate. The Village Fund had an effect on improving sanitation but it was not significant nationally or in all districts/cities. The Village Fund for drinking water had no significant effect on poverty reduction nationally and for all districts/cities. The Village Fund for sanitation had no effect on poverty reduction nationally or in all districts/cities but it had an effect on districts/cities with low fiscal capacity and poverty rate even though it was not significant. The implementation of the Village Fund policy needs to consider the fiscal capacity and diversity of regional characteristics in order to make the effectiveness of the Village Fund more optimal.
Toxicity of Malaysian Medicinal Plant Extracts Against Sitophilus oryzae and Rhyzopertha dominica
Authors: Hematpoor Arshia , Liew Sook Yee , Omar Hasmahzaiti , Shilpi Jamil Ahmad , Zahari Azeana , Syamsir Devi Rosmy , Mohd Salleh Haslinda , Tohar Norsita , Pei Theng Kim Rosalind , Qureshi Ahmad Kaleem , Nasrullah Ayu Afiqah , Chan Gomathi , Tiong Soon Huat , Ahmed Hamdi Omer Abdalla , Othman Muhammad Remy , Leong Sow Tein , Awang Khalijah , Mawi Masdah , Asib Norhayu
Published: November 2022

The insecticidal activities of extracts from 22 Malaysian medicinal plant extracts from 8 botanical families were tested against rice weevil: Sitophilus oryzae (L.) and lesser grain borer: Rhyzopertha dominica (F.). The extracts were obtained using hexane, methanol, and dichloromethane to extract potential biopesticides from dried leaves. The toxicity levels were examined periodically based on antifeedant activity and contact toxicity assays using treated grain assay. Hexane extracts of Alpinia conchigera, Alpinia scabra, Curcuma mangga, Curcuma purpurascens, Goniothalamus tapisoides, Piper sarmentosum, and methanol extracts of Curcuma aeruginosa, C. mangga, and Mitragyna speciosa were the most potent extracts against S. oryzae and R. dominica with lethal concentration (LC50) values of ≤ 0.42 mg/mL and ≤ 0.49 mg/mL, respectively. The contact toxicity test results showed that methanol extracts of C. aeruginosa and C. mangga, dichloromethane extracts of Cryptocarya nigra, and hexane extracts of C. mangga, and C. purpurascens resulted in 100% mortality of both pests within 28 days exposure of 5 mg/cm2 concentration.
Modified Nutrition Risk in Critically Ill Score, A Prognostic Marker of Morbidity and Mortality in Mechanically Ventilated Patients: A Prospective Observational Study
Authors: Dsouza Marius , Nagar Vidya S , Radhakrishnan Rahul , Pai Kalpita Suresh , Ireddy Vinay Kumar
Published: November 2022

Background: Critically ill (CI) patients, especially those requiring mechanical ventilation (MV) are at a higher risk of malnutrition, which in turn is associated with increased hospitalization and excess mortality. The modified Nutrition Risk in Critically Ill (mNUTRIC) score, a predictor of mortality, has not been validated adequately in CI Indian patients. Thus, this study evaluated the mNUTRIC score as a prognostic marker of morbidity and mortality in CI patients requiring MV. Materials and methods: This prospective observational study was performed, between January 2018 and June 2019, in the intensive critical care unit (ICCU) of the medicine department of a tertiary care hospital. A total of 250 patients aged above 12 years, admitted in ICCU, and requiring MV for >48 hours were included. Based on the data collected, mNUTRIC score was calculated and patients were classified as at low (0–4) and high (5–9) nutritional risk. Mortality was the outcome variable. Results: More than a quarter of patients had a high mNUTRIC score (28.4%) and the overall mortality was 35.6%. A significantly greater proportion of non-survivors had a high mNUTRIC score (p-value<0.0001). Likewise, the mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Sequential Organ Failure Assessment (SOFA) score, and mNUTRIC score (all p-values<0.0001) were significantly higher among the non-survivors than the survivors. On receiver operator characteristic (ROC) curve analysis, a cutoff value of >2 predicted mortality [area under the curve (AUC): 0.83; 95% confidence interval: 0.778–0.874] with a sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 80.9, 76.4, 65.5, and 87.9%, respectively. Conclusion: At a cutoff of >2, mNUTRIC score had high sensitivity and specificity in the prediction of mortality.
250 years of daily weather: Temperature and precipitation fields for Switzerland since 1763
Authors: Imfeld Noemi , Pfister Lucas , Brugnara Yuri , Brönnimann Stefan
Published: November 2022

Abstract. Climate reconstructions give insights into monthly and seasonal climate variability of the past few hundred years. However, for understanding past extreme weather events and for relating them to impacts, for example to periods of extreme floods or to yield losses, reconstructions on a daily time scale are needed. Here, we present a data set of 250 years of daily temperature and precipitation fields for Switzerland from 1763 to 2020, which has been created using early instrumental data. The temperature reconstruction shows even for an early period before 1800 with scarce data availability good results, especially in the Swiss Plateau. For the precipitation reconstruction, skills are considerably lower, which can be related to the few precipitation measurements available and the heterogeneous nature of precipitation. By means of a case study on the wet and cold years from 1769 to 1772, which triggered wide-spread famine across Europe, we show that this dataset allows more detailed analyses than hitherto possible.