bluuebunny/crossref_metadata_2025 huggingface dataset:
Segmental thoracic spinal anesthesia versus general anesthesia for breast cancer surgery: A prospective randomized-controlled open-label trial
Authors: Paliwal Naveen , Maurya Neetu , Suthar Om Prakash , Janweja Sarita
Published: December 2022

Background and Aims:

Breast surgery is associated with moderate-to-severe postoperative pain, nausea, and vomiting. For this, neuraxial anesthesia might be a better alternative to general anesthesia (GA), providing superior analgesia, with higher patient satisfaction and lesser incidence of nausea vomiting. This randomized-controlled open-label trial was done to compare segmental spinal and GA for breast cancer surgery.

Material and Methods:

The present study enrolled 56 female patients scheduled to undergo breast cancer surgery. They were randomly divided into two groups, group G (received standard GA) and group TS (received segmental thoracic spinal anesthesia with 0.5% isobaric levobupi vacaine at T5–T6 inter spaces). The primary objective of this study was patient satisfaction with the anesthetic technique, while secondary objectives were hemodynamic changes, perioperative complications, time of first rescue analgesic, total opioid consumption in first 24 h, and surgeon satisfaction score. Data were expressed as mean (SD) or number (%) as indicated and were compared using Chi-square, Fisher’s exact, or Student’s ttest as appropriate.

Results:

Patient in group TS had significantly higher satisfaction score median 5 (IQR 1) compared to patients in group G median 4 (IQR 3.5) (P = 0.0001). Nausea and vomiting were significantly higher in group G compared to group TS (P = 0.01). Mean time to rescue analgesia was 33.21 ± 7.48 min in group G as compared to 338.57 ± 40.70 in group TS and opioid consumption was also significantly lower in group TS (70.00 ± 27.38) as compared to group G (366.07 ± 59.40). There was no significant difference in hemodynamic parameters (except significantly lower heart rate at 15 min in group TS (P = 0.001) and surgeon satisfaction score between groups. Quality of postoperative analgesia was better in group TS.

Conclusion:

Segmental thoracic spinal anesthesia technique provides better satisfaction with superior postoperative analgesia and fewer complications in patients undergoing breast cancer surgery compared to GA.
Effect of pregabalin on postoperative pain and instrumentation-induced dysuria in patients undergoing percutaneous nephrolithotomy: A prospective randomized, double-blinded placebo-controlled study
Authors: Choppa Shivakrishna , Gurajala Indira , Kar Prachi , Jayaram Kavitha , Durga Padmaja , Devraj Rahul , Chilumula Ramreddy
Published: December 2022

Background and Aims:

The manipulation of urinary tract, the mandatory requirement of ureteral stenting, and bladder catheterization in patients undergoing percutaneous nephrolithotomy (PCNL) produces significant pain and dysuria postoperatively. The present study compared the efficacy of pregabalin with placebo in attenuation of these symptoms in patients undergoing PCNL.

Material and Methods:

This randomized controlled study was conducted in 110 patients of either sex, aged 18–65 years undergoing elective PCNL requiring nephrostomy tube under general anesthesia. Group G (n: 53) received pregabalin 150 mg and Group P received placebo (n: 49) orally 1 h before the anesthetic induction. All the patients received standard anesthetic protocol. Pain at the site of nephrostomy, instrumentation-induced dysuria (IID), anxiety, and sedation scores were recorded at 0 min, 15 min, 30 min, 1 h, 2 h, 4 h, 8 h, 12 h, 24 h postoperatively. Hemodynamics, total requirement of rescue analgesia, and incidence of any adverse effects were also noted.

Results:

Patients were demographically comparable between the two groups. There is no difference in nephrostomy site pain between the groups at different points of measurements. IID was less with pregabalin at 0 min, 15 min, 30 min, 1 h, and 2 h after extubation (P value < 0.05, 43% in Group G vs. 68% in group P). Severe urgency was seen in 4%, moderate in 31%, and mild in 33% of patients in placebo group. No patient in pregabalin had severe grade of instrumentation-induced dysuria score (P < 0.05). Patients in Group P required more rescue analgesic (P: 0.009). Anxiety scores, sedation scores, and hemodynamic parameters were comparable.

Conclusion:

A single dose of 150 mg pregabalin as oral premedication given 1 h before surgery reduced the incidence and intensity of IID compared to placebo in patients undergoing PCNL without significant adverse effects.
Correlation of Vitamin D Levels with Markers of Bone Metabolism in COVID-19 Patients
Authors: Agrawal Alok Chandra , Behera Ajoy Kumar , Mohapatra Eli , Sakale Harshal Suhas , Shah Seema , Kar Bikram Keshari , Ojha Mukund Madhav , Nayak Buddhadeb , Garg Ankit Kumar
Published: December 2022

Introduction:

Low serum Vitamin D levels are common in orthopedic patients in India. Low serum Vitamin D levels are implicated in COVID-19 worsening the illness. With this background, we assessed serum Vitamin D levels in COVID-19 patients presenting to us and correlated them with other markers of bone metabolism and systemic immune response.

Materials and Methods:

A cross-sectional analytical study was done on 107 COVID-19 patients. The sample was taken for serum calcium, serum Vitamin D, serum phosphate, bone-specific alkaline phosphatase (ALP), serum parathyroid hormone, creatine phosphokinase (CPK), CPK myocardial band (MB), serum protein, C-reactive protein, erythrocyte sedimentation rate, and hemoglobin in these patients. The levels were correlated with each other to assess their relations in COVID-19 patients.

Results:

One hundred out of 107 patients had low serum Vitamin D levels. In these patients, serum lactate dehydrogenase and serum ALP levels were high, and creatine kinase MB levels were low. The illness was found more in diabetic/hypertensive and rheumatoid arthritis patients. The values and findings correlate with increased disease activity and osteopenia with no obvious muscular injury.

Conclusion:

Managing Vitamin D deficiency (VDD) has been taken up as a major step in COVID-19 affection. The markers of bone metabolism and their correlation with serum Vitamin D were equivocal in COVID-19-affected and not affected Indian populations. The risk of infection has been more in diabetic, hypertensive, and rheumatoid arthritis patients, all of whom were also suffering from VDD.
“To Compare the Relative Effectiveness of Intralesional Steroid Versus Platelet-Rich Plasma Injection among 80 Patients in Plantar Fasciitis
Authors: Arya Ashish Kumar , Chandan Kumar , Kumarverma Pankaj , Kumar Santosh
Published: December 2022

Objective:

The objective of the study to compare the relative effectiveness of intralesional steroid versus platelet-rich plasma (PRP) injection among 80 patients in plantar fasciitis.

Materials and Methods:

A total number of 80 patients with plantar fasciitis were divided into two groups. Group A with 30 patients received intralesional PRP and Group B received intralesional methylprednisolone acetate injection. Pre- and post-intervention visual analogue scale (VAS), the Foot and Ankle Ability Measure (FAAM) score, and Plantar Fascia (PF) thickness for the assessment of pain relief in two groups were recorded at 6 months.

Results:

The mean VAS scores for heel pain measured after 6 months of treatment were 1.460 ± 0.6911 in PRP group and 3.024 ± 0.9572 in steroid group. The decrease in mean VAS score in both the groups was statistically significant when compared with pretreatment values (8.38 ± 0.6820 in PRP group and 8.44 ± 0.6021 in steroid group). The mean FAAM score measured after 6 months of treatment increased in both the groups (83.43 ± 5.661 in PRP group and 69.12 ± 5.795 in steroid group) when compared with pretreatment value (29.97 ± 5.997 in PRP group and 31.68 ± 6.297 in steroid group), and it was statistically significant. There was 35.90% reduction in mean PF thickness in PRP group and 28.67% reduction in steroid group as compared to baseline values after 6 months of injection.

Conclusion:

Intralesional injections of both the PRP and steroid are effective and safe modalities of treatment for plantar fasciitis. A steroid is better for short-term treatment of plantar fasciitis, but in long-term follow-up, PRP therapy is better than steroid. Both the treatment methods have caused a significant reduction in PF thickness.
Implant Density and Curve Correction in Scoliosis Surgery using a Three-Dimensional-Based Correction Strategy
Authors: Ng Bobby Kin-Wah , Illescas Victor , Chau Wai-Wang
Published: December 2022

Introduction:

The growing trend toward the use of pedicle screws for the operative treatment of patients with idiopathic scoliosis is to provide a three-dimensional (3D) deformity correction using a three-column fixation was observed. Reports have variable recommendations regarding the implant density as well as the configuration of the pedicle screws. This study re-evaluated implant density and curve correction currently based on the 3D correction strategy by comparing it to side-bending correction (SBC).

Materials and Methods:

Seventy-six adolescent idiopathic scoliosis (AIS) patients who had undergone posterior spinal fusion from 2017 to 2019 visited our specialized center were recruited. Demographic variables and radiological measurements were collected. Patients filled out the Scoliosis Research Society (SRS-22) questionnaire from a mobile device, of which the SRS-22 was digitally adopted using mobile technology and cloud computation.

Results:

In the 76 AIS patients, 28 (37%) were rigid curves and 48 (63%) were flexible curves. Of the 28 rigid curves (SBC <30%), 13 (46%) patients had low pedicle screw density (PSD), while 15 (54%) had high PSD. Of the 48 flexible curves, 26 (55%) patients had low PSD, while 22 (45%) patients had high PSD. SBC index for the high PSD group (172) is almost the same compared to the low PSD group (174).

Conclusions:

Using high or low PSD makes the same amount of spinal correction for this group and additional screws do not make significant improvement on spinal correction. Higher screw density instrumentation is associated with the same amount of correction rate, whether in rigid or flexible curves, leading us to postulate that scoliosis correction relates more to intrinsic curve flexibility rather than instrument density.
Histopathological finding of vesiculobullous lesions of skin in relation to their clinical presentation
Authors: Gupta Sudarshan , Varma Amit V. , Sharda Bela , Malukani Kamal , Malpani Garima , Sahu Harshita
Published: December 2022

Background:

Vesiculobullous disorders (VBDs) are extant with diverse clinical manifestations. Vesicles and bullae are fluid-filled cavities present within or beneath the epidermis. They are autoimmune blistering disorders in which autoantibodies are directed against target antigens present in the epidermis and dermo-epidermal junction.

Objective:

Evaluation of the various clinicodemographic profile of patients with a pattern of distribution (subtypes) of VBDs of the skin and assess the association between clinical aspects and histological changes in vesiculobullous lesions of the skin.

Materials and Methods:

The study material constituted 93 cases of VBDs out of 936 skin biopsies reported over two and a half years (January 2016 to June 2018) from the tertiary care center. A detailed history of the patients was taken, and a complete physical and dermatological examination with findings including clinical diagnosis was recorded. Histopathological examination (incisional/excisional/punch biopsy) was done in each case. The clinico-demographic evaluation was done and the results were correlated with histopathological findings.

Results:

Vesiculobullous lesions constituted 10.06% of all skin biopsies. The majority of cases were of pemphigus vulgaris (PV) 30 (32.25%) followed by 16 (17.2%) of bullous pemphigoid. In 83 cases (89.24%) histopathology findings were consistent with clinical diagnosis. Out of 34 cases that were diagnosed clinically as PV, the histopathological study proved 30 cases (88.23%) as PV.

Conclusion:

Vesiculobullous lesions of the skin are a heterogeneous group of disorders. It is essential to differentiate each pattern of subtype based on clinical examination and histopathological findings. Histopathological diagnosis with clinical correlation plays a major role in arriving at the diagnosis.
Effect of dynamic cupping therapy vs. vibrating foam roller on pain, range of motion, function, and quality of life in elderly with subacute and chronic osteoarthritis of knee
Authors: Kanabur Vijayalaxmi , Muragod Anil R.
Published: December 2022

Background:

Knee osteoarthritis (KOA) is a frequent degenerative disease of joints. The prevalence is approximately 28% among the Indian elderly. Recently complementary and alternative medicine therapies have been used in managing pain and disability. Dynamic cupping therapy is one of the forms used nowadays. Foam rolling and vibration therapy is also a popular intervention in musculoskeletal conditions such as osteoarthritis, osteoporosis, sarcopenia, and low back pain. Nowadays, these two have been combined for the development of vibrating foam rollers.

Objectives:

This research aimed to compare the result of dynamic cupping therapy to that of a vibrating foam roller on pain, range of motion, function, and quality of life in elderly with sub-acute and chronic KOA.

Materials and Methods:

The research was carried out on 45 subjects with subacute to chronic KOA who were given thrice a week sessions for 4 weeks’ intervention. Through the randomized method, subjects were divided into a conventional group, dynamic cupping group and vibrating foam roller group outcome measures Numeric Pain Rating Scale, knee range of motion, Western Ontario and McMaster Universities Arthritis Index (WOMAC), and brief Older People's Quality of Life Questionnaire (OPQOL-brief) were used.

Results:

Wilcoxon rank test revealed a pre-post difference in all three groups with significant P-values which were <0.05 and heterogeneously favored different outcome measures used. Kruskal–Wallis test revealed no difference between the groups.

Conclusion:

This study concluded that dynamic cupping therapy and vibration foam roller protocols used for the management of KOA are equally effective.
Hermeneutic phenomenology of lived experience of family caregivers of critically-ill patients sustained by healthcare technologies in Benin City, Nigeria
Authors: Olorunfemi Olaolorunpo , Nwozichi Chinomso Ugochukwu
Published: December 2022

Background:

Critical illness causes a severe financial impact on households not only because of illness-related inability to work but also because of the cost of medical care. Although the patients have the potential for recovery, they are usually presented with a life-threatening situation. Our study aimed to explore the lived experience of family caregivers caring for critically-ill patients.

Materials and Methods:

A qualitative study using a hermeneutic phenomenological design, to explore the lived experience of ten family caregivers caring for critically-ill patients admitted to the University of Benin Teaching Hospital, Benin-city in 2022. This study followed a hermeneutic phenomenological design using an in-depth interview of ten family caregivers who met the inclusion criteria: a family member who participated actively in the care was included. Data were collected, transcribed, and analyzed using Nvivo software and Paul Ricoeur’s theory for interpretation.

Results:

Based on Paul Ricoeur’s theory of interpretation, five themes were identified as the experience of family caregivers: caring neglect, psychological support, and words of encouragement, lack of confidence in nursing intervention, hopeless situation, and financial burden.

Conclusion:

This study shows that understanding the experience of family caregivers provides better and quality care. It also found that the hospital management needs to be aware of the identified caring neglect among family caregivers and provide a comprehensive health policy to accommodate their physiological needs while in the hospital
Extensive atherosclerosis associated with mobile thrombus in the left carotid bulb in an elderly
Authors: Dwivedi Shridhar , Ashfaq S. , Riyaz T.
Published: December 2022

A case of extensive atherosclerosis in an 88-year-old, chronic heavy smoker, associated with mobile thrombus in the left carotid bulb is presented. This patient also suffered from chronic obstructive pulmonary disease (COPD) and hypertension. He was fully worked up and confirmed as a case of the mobile thrombus attached to the plaque in the left carotid bulb by echocardiography and carotid Doppler. Thrombolysis of a large, mobile clot poses a theoretical risk of stroke worsening from incomplete fibrinolysis. He was prescribed anticoagulants and has been doing fine till the last follow-up. The importance of preventing premature atherosclerosis in the next generations is also discussed. We report this case to create awareness about this preventable malady and treatment options.
Tuberculosis of the tongue
Authors: Dahiphale Devidas B. , Nagarpurkar Abhijeet , Sharma Harshul , Pole Shivaji , Mishrikotkar Prasanna S.
Published: December 2022

Introduction:

Tuberculosis mostly affects the lungs, but may also affect the central nervous system, lymphatic system, circulatory system, genitourinary system, bones, joints, and skin. Extrapulmonary involvement in tuberculosis is rare, accounting for just 10 to 15% of cases. The lymph nodes are the second most common site of tuberculosis infection. Oral tuberculosis has long been thought to be an unusual phenomenon. Oral manifestations are thought to occur in just 0.05 to 5% of all tuberculosis cases. Surface ulcers, patches, papillomatous lesions, and indurated soft tissue lesions are the most common oral manifestations.

Case Presentation:

A 69-year-old man presented to the Department of Ear, Nose, Throat at MGM Hospital in Aurangabad, India, with a painful ulcer and tiny nodules on the tongue’s tip and lateral surface. The ulcer appeared 3–4 weeks ago without any obvious trigger with a prickling feeling and increased soreness over the area., Onintraoral inspection multiple small nodules is measuring about 0.1 cm and multiple circular ulcer measuring about 0.2 x 0.1 cm in diameter at the tip and lateral border of the tongue. A granulomatous center and a whitish, well-defined border with mild elevation characterized the ulcer.

Conclusion:

Despite the rarity of tuberculosis evidence in the oral cavity, oral tuberculosis should be included in the differential diagnosis of chronic oral lesions. To prevent ineffective oral therapy, accurate diagnosis is crucial for successful care by concentrating on the pathological source.
Sanitation and hand washing behavior of urban slum dwellers in Vellore Corporation of Tamil Nadu, India
Authors: Nirmalkumar K. , Sivasankar V.
Published: December 2022

Objectives:

This study examines the sanitation and hand-washing behavior of slum dwellers before coronavirus disease 2019 (pre-COVID-19) and during the COVID-19 period. The study also examines health-seeking behavior.

Materials and Methods:

Purposive sampling method was used to select the study area and household. Out of 49 registered slums in the Vellore municipality corporation, three slums were selected, which represent the highest number of slum households. The names of the urban slum settlement were Salavanpet, Old Town, and Makkan. After selecting the study areas, households were selected on snowball techniques through telephonic conversation with a structured interview schedule. The total samples were 75 households. The study period was from June 2021 to August 2021.

Results:

The study shows that Vellore has the 18th highest number of positive COVID-19 cases in Tamil Nadu. This study found that regular wage incomes in urban slum dwellers have been severely affected by COVID-19 lockdowns. The majority of households without a toilet in slums have used open defecation during COVID-19. Hand washing behaviors for people living in the urban slums have increased during the COVID-19 than the pre-COVID-19 pandemic. This study found that middle-aged (age 31–40 years) people’s habit of hand washing as a precautionary measure against coronavirus disease increased during COVID-19 compared with pre-COVID-19.

Suggestion and Conclusion:

The study suggests that improving hand-washing habits could aid in the prevention of the COVID-19 virus and other illnesses and suggests advancing hand washing habits after the pandemic as basic protective measures, which continues to remain essential in urban areas.
Assessment of anti-inflammatory activity of Tridax procumbens in wistar rats
Authors: Prakash Sandeep , Suman Rajesh Kumar , Chandra Gulab , Yadav Priti , Kumar Manish
Published: December 2022

Background:

Tridax procumbens Linn. is a spreading herb found throughout India. Tridax procumbens is known for several potential therapeutic effects like antiviral, antioxidant, anti-infective, wound healing, insecticidal and anti-inflammatory, hepatoprotective, and antidiabetic. Novel therapies for inflammation are essential to overcome the adverse effects of existing anti-inflammatory drugs. Thus, this study was designed to evaluate anti-inflammatory activity in the experimental animal.

Objective:

To evaluate anti-inflammatory efficacy in experimental animal

Materials and Methods:

Tridax procumbens plant leaves were taken for the study. The Plant extraction was prepared by using the Soxhlet apparatus. The ethanolic extract was used as a test drug. Indomethacin and Dexamethasone were used as control drugs. Wistar rats weighing 150g to -200g were used in the study.

Results:

At dosages of 200 and 400 mg kg-1, the ethanolic leaf extracts of Tridax Procumbens demonstrated substantial anti-inflammatory activity against Irish Moss-triggered inflammation. After 3 hours, 400 mgkg-1 showed a significant reduction in inflammation (48 percent), with the impact increasing after 3 hours (52 percent). The anti-inflammatory efficacy of Tridax Procumbens ethanol (EtOH) extracts was substantial and comparable to that of indomethacin (10 mg/kg). Tridax procumbens ‘s Ethanol (EtOH) leaf extract at a dose of 200 and 400 mgkg-1, demonstrated considerable anti-inflammatory action. The average weight of granulomatous surrounding tissue in the threading was considerably smaller in the Tridax procumbens extraction group after 7 days than in the comparison group. The 400 mg kg-1 dose was shown to be the most effective of the two. the greatest reduction in the production of granuloma tissue. Tridax procumbens at doses of 200 mg/kg and 400 mg/kg resulted in substantial reductions in granuloma weights of 38.16 ± 0.04 (7.4 percent inhibition) and 34.58 ± 0.04 (16.1 percent inhibition), respectively. The lower dose of 400 mg/kg resulted in a little lesser reduction in granumola weight than the conventional medication dexamethasone (28.92 ± 0.04). (29.8 percent inhibition).

Conclusion:

The present study concludes that Tridax Procumbens possess anti-inflammatory effects in animal models.
In vitro maturation (IVM) procedure in oncofertility patients
Authors: Ahmad Mohd F. , Sugishita Yodo , Suzuki-Takahashi Yuki , Iwahata Hideyuki , Takae Seido , Horage-Okutsu Yuki , Suzuki Nao
Published: December 2022

Our review aims to evaluate the benefit of in vitro maturation (IVM) in a standard control ovarian stimulation among oncofertility patients. A thorough search for relevant studies was conducted via PubMed, Google Scholar, Scopus, Cochrane Library, and clinical.gov databases. Our primary outcome was the oocyte maturation rate (OMR), which measures the number of immature oocytes that progress to mature (MII) oocytes following IVM. Our secondary outcomes were the number of oocytes and embryo cryopreservation following IVM for future use. The initial search identified 150 studies. Eight studies were included in our review after duplication assessment, title and abstract screening, and subsequent complete text evaluation tailored to our inclusion criteria. A total of 1040 patients with cancer with a mean age of 32.68 years were included in our review, in which half of them were diagnosed with breast cancer (BC). Most of the cycles were unstimulated. Two studies compared IVM in either follicular or luteal phases, and one study compared the in vitro fertilization (IVF) cycle with or without IVM. Our review included 7711 oocytes with 4604 oocytes that progressed to MII, obtaining an overall OMR of 59.70%. Following IVM, 335 embryos and 2380 oocytes were cryopreserved for future use. The oocyte numbers and maturation were comparable among all the studies, except that prognostic and predictor BC affects the IVM outcome. Our review concluded that IVM improves the number of MII following IVF cycles with similar survival rates, meiotic resumption rates, and blastocyst formation upon fertilization. Thus, IVM is a beneficial strategy for oncofertility patients.
COVID-19 and male fertility
Authors: Kaul Nalini
Published: December 2022

COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented global health crisis. The virus entry into the host cell is facilitated by the coexpression of angiotensin-converting enzyme 2 (ACE2) and TMPRSS2 receptors. The male genital system is vulnerable to infection because of the presence of ACE2 and TRMPSS2 on the spermatogonial and somatic cells. Testicular damage leading to the impairment of spermatogenesis and semen parameters has been documented, though the exact mechanism of testicular injury is not confirmed. Immune response to infection, dysfunction of the steroidogenic pathway, impairment of the blood–testes barrier, and fever per se are implicated. The alteration in semen parameters has been demonstrated with COVID-19 infection leading to reproductive compromise. The recovery of semen parameters occurs within 3 months of the infection. It is recommended to wait for 3 months after infection to start infertility treatment. The possibility of sexual transmission and vertical transmission remains a concern, even though the virus has not been detected in semen in most studies. Fertility preservation procedures (semen and testicular tissue cryopreservation) must not be deferred because of their time-sensitive nature. Safety protocols to prevent crosscontamination in cryostorage and to maintain the safety of laboratory personnel should be strictly adhered to. ESHRE and ASRM recommend screening patients before initiating fertility preservation procedures. Testing semen samples for SARS-CoV-2 by RT-PCR has also been advocated to improve safety. Long-term follow-up should be considered in men and young boys exposed to infection and in children conceived during the infection. Vaccination for COVID-19 should be promoted as it does not compromise male fertility.
There are no exotic actions of diffeomorphism groups on 1-manifolds
Authors: Chen Lei , Mann Kathryn
Published: December 2022

Let

M

be a manifold and

N

a

1

-dimensional manifold. Assuming that

r\neq\dim(M)+1

, we show that any nontrivial homomorphism

\rho:\mathsf{Diff}^r_c(M)\rightarrow\mathsf{Homeo}(N)

has a standard form: necessarily

M

is

1

-dimensional, and there are countably many embeddings

\phi_i: M\rightarrow N

with disjoint images such that the action of

\rho

is conjugate (via the product of the

\phi_i

) to the diagonal action of

\mathsf{Diff}^r_c(M)

on

M\times M\times\cdots

on

\bigcup_i\phi_i(M)

, and trivial elsewhere. This solves a conjecture of Matsumoto. We also show that the groups

\mathsf{Diff}^r_c(M)

have no countable index subgroups.
Computing the spectral action for fuzzy geometries: from random noncommutative geometry to bi-tracial multimatrix models
Authors: Pérez-Sánchez Carlos I.
Published: December 2022

A fuzzy geometry is a certain type of spectral triple whose Dirac operator crucially turns out to be a finite matrix. This notion incorporates familiar examples like fuzzy spheres and fuzzy tori. In the framework of random noncommutative geometry, we use Barrett’s characterization of Dirac operators of fuzzy geometries in order to systematically compute the spectral action

{S(D)= \operatorname{Tr} f(D)}

for

2n

-dimensional fuzzy geometries. In contrast to the original Chamseddine–Connes spectral action, we take a polynomial

f

with

f(x)\to \infty

as

\vert x\vert \to\infty

in order to obtain a well-defined path integral that can be stated as a random matrix model with action of the type

{S(D)=N \cdot \operatorname{tr} F+\sum_i \operatorname{tr}A_i \cdot \operatorname{tr} B_i }

, being

F

,

\smash{A_i}

and

B_i

noncommutative polynomials in

\smash{2^{2n-1}}

complex

N\times N

matrices that parametrize the Dirac operator

D

. For arbitrary signature—thus for any admissible KO-dimension—formulas for

2

-dimensional fuzzy geometries are given up to a sextic polynomial, and up to a quartic polynomial for

4

-dimensional ones, with focus on the octo-matrix models for Lorentzian and Riemannian signatures. The noncommutative polynomials

F

,

\smash{A_i}

and

B_i

are obtained via chord diagrams and satisfy: independence of

N

; self-adjointness of the main polynomial

F

(modulo cyclic reordering of each monomial); also up to cyclicity, either self-adjointness or anti-self-adjointness of

\smash{A_i}

and

B_i

simultaneously, for fixed

i

. Collectively, this favors a free probabilistic perspective for the large-

N

limit we elaborate on.
Quasi-periodic motions in generic nearly-integrable mechanical systems
Authors: Biasco Luca , Chierchia Luigi
Published: December 2022

In this note, we present and briefly discuss results, which include as a particular case the theorem announced in [Rend. Lincei Mat. Appl. 26 (2015), 423–432], concerning the typical behavior of nearly-integrable mechanical systems with generic analytic potentials.
Уязвимость квантовой криптографии с фазово-временны́м кодированием в условиях затухания
Authors: Kronberg Dmitry Anatolevich
Published: December 2022

Протокол квантовой криптографии с фазово-временны́м кодированием использует конфигурацию состояний с разделением на базисы, располагающиеся в различных временны́х окнах, из-за чего информация перехватчика оценивается на основе двух параметров. Показано, что при анализе стойкости протокола не были учтены некоторые атаки, использующие затухание в линии связи. Построена атака, которая явно демонстрирует уязвимость протокола: уже при сколь угодно малой длине линии связи протокол полностью теряет стойкость, т. е. перехватчику становится известен весь криптографический ключ.
The Estimation of Blue-green algae Cell Count and Phycocyanin Concentration using Fluorescent Concentration analyzer
Authors: Choi Jaeyun , Park Yelim , Lee Sujeong , Kim Kwangsoo , Kim Youngdo , Kwon Jaehyun
Published: December 2022

Objectives:The purpose of this study is to provide basic data for the development of a rapid and easy to measure alternative indicator for estimating the number of cyanobacteria cells in the field.Methods:Phycocyanin, algal cell number, and water quality items were measured at the left, middle, and right points of Maery Bridge near the Mulgeum and Maery algae monitoring network located downstream of the Nakdong River. The phycocyanin concentration(PC) was measured in the field using the LISST-HAB sensor, which is a fluorescence concentration analyzer, and comparative analysis was performed with the number of algal cells by algae species.Results and Discussion:As a limiting factor for blue-green algae occurrence, the correlation coefficient (r) between T-P and Blue-green algae (BGA) was 0.58 (≥0.3). Phycocyanin and Blue-green algae showed a high significant correlation at 0.96 (≥0.3). Prob (F-statistics) of the blue-green algae cell count estimation formula using phycocyanin was less than 0.05, showing a significant result. The estimation formula was estimated BGA(cells/mL) = 326.95×PC+50,484. As a result of the analysis of the predicted and measured values of Blue-green algae, r2 was 0.988, indicating a high coefficient of determination and 92.5% accuracy.Conclusion: The correlation analysis with the number of cyanobacteria showed a high significant correlation with phycocyanin of 0.96 (≥0.3), followed by T-P, a limiting factor for the occurrence of cyanobacteria, of 0.58 (≥0.3) indicating a significant correlation. In addition, the formula for estimating the number of blue-green algae cells using phycocyanin was found to be BGA (cells/mL)=326.95×PC+50,484 in which r2 was 0.927, and Prob (F-statistics) was less than 0.05. As a result of analyzing the predicted and measured values ​​of cyanobacteria cell numbers, r2 was 0.988, indicating a high coefficient of determination, with accuracy of 92.5%. Through this results, it reveals that the number of cyanobacteria cells can be estimated using the sensor of the fluorescence concentration analyzer at the target point by substituting the phycocyanin concentration into the blue-green algae cell number estimation formula.
Current Status and Perspectives of Carbon Capture and Storage
Authors: Lee Sanghyeok , Lee Mugung , Jeon Woong , Son Minseok , Jung Sokhee P.
Published: December 2022

As climate change progresses rapidly, unprecedented weather and natural changes are occurring. After carbon dioxide was identified as the main culprit of global warming and climate change, at the UN General Assembly in 2015, 195 countries signed the Paris Agreement to set greenhouse gas emission reduction targets. However, some countries are either withdrawing from the Paris Agreement or failing to implement it due to their own economic reasons. Reducing the use of fossil fuels increases energy costs. In this context, carbon capture and storage technology (CCS) is emerging as an alternative. In this review, the outline of CCS technology is explained, and the advantages and disadvantages of each technology, the status of CCS technology, and commercialization cases are investigated and analyzed. In addition, for an in-depth analysis of the CCS technology itself, the following issues were analyzed in depth during the research and analysis process: 1) Efficiency of CCS technology, 2) Comparison of carbon capture and storage capacity between CCS technology and vegetation, 3) Stability of carbon storage through CCS technology. Finally, the policy for carbon capture and storage technology and the development direction of this technology were presented.
Diaspora reconnection with homeland religion, cultural and heritage festival celebration
Authors: Umejei Aboshioke Lilian
Published: December 2022

This study was undertaken to examine and gain better understanding of the impact that “modernization” or “urbanization” has on members of the diaspora community. Using the Osun Osogbo festival in Nigeria as a case study, the study examined the perception of these members of the Nigerian diaspora community to the festival, their notion of cultural tourism celebration and their desire to participate. The study explored these migrants’ reservations with celebration activities at the Sacred Grove during the festival. This exploratory study employed a qualitative research design based on in-depth interviews to elicit data. The target population were first-generation Nigerian migrants of Yoruba descent who live in South Africa. Findings from the migrants’ experiences revealed that their reluctance was due to their reservation on the spiritual or religious undertones attached to these spiritual festivals. Many of these returning migrants no
longer desire to be identified with local religious or spiritual celebrations. By tapping into tourism and heritage, the study thus submits that, enhancing the relevance of the grove and the festival, as a tool to improve cultural and heritage tourism will best be achieved if religion can be separated from cultural celebrations.
Hitna neonatologija mačića
Authors: Klašterka Klara , Butković Ivan , Grizelj Juraj , Getz Iva , Prvanović Babić Nikica , Samardžija Marko , Špoljarić Branimira , Folnožić Ivan , Lojkić Martina , Vince Silvijo , Bačić Goran , Šavorić Juraj , Karadjole Tugomir , Maćešić Nino
Published: December 2022

U životu mladunčadi mačića neonatalno razdoblje predstavlja prva dva do tri tjedna života. U tom razdoblju novorođenčad je u potpunosti ovisna o majci. Mladučad reagira samo na bol, dodir i miris, a razvijene su im samo motoričke funkcije. Smrtnost mačića u dobi od jednog do sedam dana je do 85 %, što je vrlo visok postotak uginuća. Glavni uzrok neonatalnog mortaliteta je hipoksija, gotovo uvijek praćena s hipotermijom, hipoglikemijom i dehidracijom. Ova četiri hitna stanja najčešće se pojavljuju odjednom i potrebno ih je rješavati pravilnim redoslijedom da ne bi prouzročili veću smrtnost. Za liječenje i dijagnosticiranje ova četiri hitna stanja potrebno je razumjeti fiziologiju novorođenčadi. Novorođenčad prespava 80 % tijekom dana, a jesti trebaju svaka dva do četiri sata. Centar za termoregulaciju nije potpuno razvijen do dobi od šest tjedana. Tjelesna temperatura novorođenčadi ovisi o temperaturi okoliša, imaju mali postotak masnog tkiva i stoga su skloni razvoju hipotermije, koju uvijek treba riješavati zbog začaranog kruga koji se može razviti ako se hrani hipotermično novorođenče prije hipoglikemije. Jetra nije potpuno razvijena do dobi od osam tjedana pa stoga procesi glukoneogeneze i glikogenolize nisu aktivni, a razina glukoze ovisi samo o gutanju, odnosno o hranjenju. Zbog nedostatno razvijenih bubrega i nemogućnosti koncentriranja urina, povećane propusnosti kože i smanjene mogućnosti autoregulacije protoka krvi kroz bubrege neonatalni su bolesnici skloni i razvoju dehidracije. Nerazvijena jetra i bubrezi tako utječu i na lijekove koji se mogu koristiti. Klinički znaci bolesnog mačića su: neprestalni plač, anemična ili cijanotična sluznica, proljev i slabost, nedobivanje na tjelesnoj težini, mršavljenje i bradikardija. Za svakog bolesnog neonatalnog pacijenta potrebno je napraviti kompletan pregled uz vađenje krvi i određivanje hematoloških i biokemijskih parametara. Tumačenje krvnih parametara je drugačije nego u odraslih jedinki i potrebno ga je u skladu s time tumačiti. U slučaju zastoja ili perzistentne bradikardije potrebno je napraviti ABCD protokol.
Convective Flow of Blood through a Constricted Cylinder and the Effect of Cholesterol Growth Rate on the Motion in the Presence of a Magnetic Field
Authors: Bunonyo K. W. , Amos E.
Published: December 2022

An inflammatory disease resulting in the pathological constriction of the intima and media of the arterial system, such as the aorta, causes symptoms like stroke, heart attack, or angina; This research investigates the convective flow of blood through a constricted cylinder and the effect of cholesterol growth rate on the motion in the presence of a magnetic field by transforming the problem into a system of time-dependent partial differential equations. The governing partial differential equations (PDEs) were transformed into dimensionless ordinary differential equations (ODEs) and solved using the Laplace method. After obtaining the analytical solution, Wolfram Mathematica was used to perform the numerical computation where the various physical parameters such as Soret number, radiation number, solutal Grashof number, Schmidt number, and Prandtl number were varied to their impact studied. The study discovered that increasing the Soret number causes an increase in blood velocity, whereas decreasing the Solutal Grashof number decreases blood velocity. Furthermore, an increase in radiation parameter increases the blood velocity, but a Soret number increase results in a decrease in the concentration of cholesterol in the fluid, a Schmidt number, and oscillatory frequency increase, causing the temperature to decrease. This research is useful for clinicians and mathematical modellers who are trying to understand the flow of cholesterol saturated fluid in the human vascular system and how best to proffer analytical and numerical solutions in synergy with laboratory investigation.
MANUFACTURING AND CHARACTERIZATON OF WAAM-BASED BIMETALLIC CUTTING TOOL
Authors: GÜROL Uğur , DİLİBAL Savaş , TURGUT Batuhan , BAYKAL Hakan , KÜMEK Hülya , KOÇAK Mustafa
Published: December 2022

Wire-arc additive manufacturing (WAAM) is a promising method to produce many functional components in different industries. In this method, the welding wires from the feedstock are melted by arc discharge and deposited layer by layer. Other welding wires having different chemical compositions can also be added to the top of the previously deposited layer by replacing the feed wire from the stock to produce bimetallic components. This study investigated the feasibility of using robotic wire arc additive manufacturing technology to produce a bimetallic cutting tool. The bimetallic cutting tool was produced by depositing MSG 6 GZ-60 hard-facing welding wire on top of the austenitic stainless-steel wall produced with ER 316LSi solid wire. The cutting-based equipment requires an increased abrasion resistance with the combination of ductility to provide adequate tool life and performance. Thus, detailed microstructural analysis and hardness tests were conducted to understand the general microstructural characteristic of the manufactured cutting tool, including interfaces between two different materials.
Development of emotional skills in schoolchildren with special educational needs in Primary Schooll
Authors:   ", CIOBANU Adriana ,   Ion Creangă",   SPU, Chișinău, URSU Miluța ,   "Ion Creangă" SPU, Chișinău
Published: December 2022

Education is an extremely complex and profound process. Education based on emotional intelligence starts from the fact that all the action, both important and small, ones allow the creation of a healthy balance in relationships with children. Actions must emphasize the importance of feelings and help us and our children, control our emotions, instead of actiong impulsively or being overwhelmed by feelings.
Psycho-pedagogical assistance for cildren with hearing disabilities
Authors:   ", CIOBANU Adriana ,   Ion Creangă",   SPU, Chișinău
Published: December 2022

The psycho-pedagogical assistance of children with hearing impairment is complex, multilateral and interdisciplinary. Which is of major importance because hearing loss at a younger age makes it impossible to develop normal language and, implicitly, the child's thinking, with serious consequences in terms of his mental development and personality traits. For this reason, early diagnosis of hearing loss, followed by early hearing aids and psychopedagogical and speech therapy intervention is the most effective way to successfully include school children with hearing impairments.
He study of the personality of delinquent adolescents
Authors:   ", RACU Igor ,   Ion Creangă",   SPU, Chișinău, NICOLAESCU Eliza Penelopa ,   Psychiatric hospital Eftimie Diamandescu,București
Published: December 2022

This article is a brief presentation of the results obtained in the doctoral research "Development of the personality of delinquent adolescents". A comparative experimental research on personality development in delinquent and non-delinquent adolescents was conducted, differences in their personality profile were established, the clinical profile of adolescents with delinquent patterns was assessed, maladaptive coping strategies and the level of moral development of adolescent offenders were determined. the development of the personality of delinquent adolescents through the implementation of a formative program of dual psychological intervention having as major objective the decrease of the delinquent potential.
Self-esteem and anxiety in preadolescent
Authors:   ", CHIREV Larisa ,   Ion Creangă",   SPU, Chișinău
Published: December 2022

The article contains a short theoretical foray into defining the concepts of anxiety and self-esteem and analyzing the empirical results obtained. It was found that most preadolescents are characterized by average reactive and stable anxiety, the self-esteem of most study participants is average. Gender differences were found in the manifestation of anxiety and self-esteem in preadolescents, especially in 5th grade students. Significant indirect relation between anxiety and self-esteem in preadolescents has been demonstrated.
VALIDITAS DAN RELIABILITAS TERHADAP INSTRUMEN KEPUASAN KER
Authors: Slamet Rokhmad , Wahyuningsih Sri
Published: December 2022

Research instruments with appropriate and consistent measuring instruments in research can be carried out with validity and reliability tests. Validity test can be done using Corrected Item to Total Correlation method and reliability test using Cronbach's Alpha method. The test uses a two-sided test with a significance level of 0.05 or 5%.Data retrieval using Google Forms with a trial of 50 respondents in the form of ordinal data with SPSS tools analyzed by variability test using Corrected Item to Total Correlation method and reliability test using Cronbach's Alpha method.As many as 4 instrument numbers out of 50 instrument numbers were declared invalid, namely numbers 7, 9, 12 and number 14, while the other instrument item numbers were declared valid. In the reliability test using Cronbach's Alpha method with Cronbach's Alpha value of 0.987 0.60 then all the instrument questions are declared reliable.
PENGARUH LINGKUNGAN KERJA FISIK DAN NON FISIK TERHADAP STRES KERJA KARYAWAN PT CITRA ABADI SEJATI
Authors: Maryani Ani , Darmanto Rochmad Fadjar , Ariyanti Anik , Sunarso Sunarso
Published: December 2022

This study aims to determine the influence of the physical work environment and nonphysical work environment on employee work stress at PT Citra Abadi Sejati. This research was conducted at PT Citra Abadi Sejati in a population of 550 employees. A sample of 85 people was taken from stratified sampling techniques. The data collection method uses observation and dissemination of questionnaires. Data analysis method with validity test, reliability test, model test, and classical assumption test. The results showed that the physical work environment has a positive and significant influence on employee work stress. Likewise, the nonphysical work environment has a positive and significant influence on the work stress of PT Citra Abadi Sejati employees.