bluuebunny/crossref_metadata_2025 huggingface dataset:
Christine Greenhalgh e Mark Rogers - Innovation, Intellectual Property and Economic Growth
Authors: Esteves Luiz A.
Published: June 2017

O livro publicado por Greenhalgh e Rogers foi produzido para servir como manual para os cursos de economia da inovação, economia do crescimento econômico e propriedade intelectual. A ideia é que o material seja utilizado por alunos dos últimos anos de cursos de graduação ou cursos introdutórios ao nível de pós-graduação stricto sensu, mas também pode ser indicado, de forma bastante satisfatória, para outros formatos de cursos de pós-graduação, tais como os de especialização lato sensu e MBAs nas áreas de inovação, propriedade intelectual e empreendedorismo. Adicionalmente, o livro ainda tem o formato ideal para atender às necessidades de vários cursos de mestrado profissionalizante no país, principalmente nas áreas de administração, economia, direito, ciência e tecnologia e propriedade intelectual.
Editorial
Authors: Suzigan Wilson , Garcia Renato
Published: June 2017

Com este primeiro fascículo de 2014, a Editoria da Revista Brasileira de Inovação tem a satisfação de iniciar seu 13o ano de publicação. Ao longo desse período, a RBI vem se consolidando como um veículo de importância crescente no debate sobre as questões ligadas à Economia e à Gestão da Inovação, bem como em áreas subjacentes, com evidentes desdobramentos de políticas e implicações gerenciais. Os resultados alcançados em 2013 demonstram claramente a projeção da revista. Primeiro, cabe mencionar que durante 2013 foi recebida a submissão de exatos 100 artigos originais e inéditos, superando 2012 e 2011, com, respectivamente, 79 e 75 textos submetidos. Segundo, a consolidação da RBI como veículo de crescente importância para o debate acadêmico pode ser comprovada pela elevação da sua classificação no Qualis da Capes, que passou para B1 na área Interdisciplinar e B2 na Economia; além da classificação B2 na área de Administração, Ciências Contábeis e Turismo. Em termos dos indicadores de impacto, pode-se apontar que a RBI recebeu 30.000 novos acessos ao site da revista em 2013, conforme dados coletados pelo Google Analytics. Por fim, a Revista Brasileira de Inovação reafirma seu compromisso com a eficiência do processo de avaliação dos artigos submetidos, uma vez que o tempo médio para a comunicação da primeira decisão editorial aos autores foi de 49 dias em 2013. Todos os indicadores da RBI estão no Relatório Anual de Atividades 2013, disponível aos leitores no site da revista (http://www.ige.unicamp.br/ojs/index.php/rbi).
Genetic variability of three fish species of genus Puntius
Authors: H. Abu-Almaaty A. , Bahgat Iman M. , Al-Tahr Zaineb M.
Published: June 2017

The present study was aimed to evaluate the genetic variability among three fish species of genus Puntius, Puntius semifasciolatus, Puntius conchonius and Puntius oligolepis (family: Cyprinidae) using various genetic markers (SDS-Page and ISSR). The electrophoretic analysis of protein was revealed 29 bands of molecular weight ranging from 11 to 132KD with polymorphism 28%. A total of eleven ISSR primers produced 123 total bands their size ranged from 79 to 1185bp and the percentage of polymorphism ranged from 91% to 100%. Results analysis showed that the percentages of genetic relationship among three species were 33% and 47%. The results of the study revealed that Puntius semifasciolatus and Puntius conchonius have higher genetic similarity 47% while Puntius semifasciolatus and Puntius oligolepis exhibited lower genetic similarity 33%. Considering all the gained data, it is evident that molecular detection of SDS-Page and ISSR are suitable tools in assessing genetic variation among fish species. These markers provide interesting tools for breeding new varieties of Egyptian fish.
O ESFORÇO DO SETOR AGRÍCOLA PARA INFLUENCIAR A AGENDA BRASILEIRA NA RODADA DOHA
Authors: Mancini Claudia
Published: June 2017

Em dezembro de 2001, os membros da Organização Mundial do Comércio (OMC)
chegaram a um acordo para lançar a Rodada Doha de Desenvolvimento (RDD), a mais
complexa do sistema multilateral do comércio até hoje. Nessa negociação, o Brasil tem
utilizado o G-20 como o principal canal para defender seus interesses ofensivos no
agronegócio perante seus interlocutores. As demandas apresentadas passam por
discussões dentro do país, com boa parte delas – senão todas – sendo discutidas com
representantes do setor privado. Essa discussão tem se dado por meio de canais formais e
informais, alguns deles criados pelo Executivo nos últimos anos. Com o forte salto na
competitividade do agronegócio, esse setor passou a ocupar espaço privilegiado na
agenda internacional e ofensiva do Brasil. O setor privado tem acompanhado essa
mudança – ou até mesmo incentivado isso, demonstrando maior preparação para defender
sua própria agenda e tentar influenciar a do governo.
ACCOUNTABILITY PARA A PAZ PERPÉTUA
Authors: Boscov Camila
Published: June 2017

Com o fim da Guerra Fria ocorreu a ampliação da participação de organizações não governamentais no cenário internacional. O objetivo do trabalho é entender o processo de accountability destas instituições como instrumento de legitimação da atuação destas no sistema internacional, já que não são sujeitas as normas que valem a uma democracia. Ao final se conclui que legitimação da atuação de uma organização não governamental pode ser alcançada por meio do processo de accountability e os atributos deste processo dependerão de características individuais da organização, como, seu nível de formalidade, proximidade com os stakeholders, identificação com os valores e visibilidade.
O QUE OS GERENTES “APRENDEM” NOS CURSOS DE ESPECIALIZAÇÃO?
Authors: Grohmann Márcia Zampieri
Published: June 2017

Este estudo buscou compreender o impacto que um curso de pós-graduação lato sensu, teve na aprendizagem gerencial. Assim, foi realizada uma pesquisa qualitativa e longitudinal com gerentes que possuíam pouca experiência profissional. As entrevistas foram divididas em duas etapas: a primeira no início do curso e a segunda no final do curso. Em ambas, foram identificadas as percepções dos gerentes sobre suas competências. Através de análise comparativa destas narrativas identificou-se que o curso gerou: ampliação de algumas habilidades e valorização de outras; a aquisição de novos conhecimentos (principalmente voltados às tarefas); e poucas mudanças de atitude.
A RACIONALIDADE POR TRÁS DAS FUNÇÕES RITUALÍSTICAS: DESVENDANDO A ILUSÓRIA IRRACIONALIDADE DO MUNDO DOS NEGÓCIOS
Authors: Pereira Rafael Diogo , Muniz Reynaldo Maia , Calbino Daniel
Published: June 2017

Partindo da percepção de que nas organizações existem diversas ações, políticas e condutas que, ao menos aparentemente, podem ser interpretadas como irracionais, o presente artigo teve por objetivo discutir qual seria a lógica por trás de tais atos. Neste sentido, foram abarcadas as contribuições teóricas oferecidas pela Teoria da Ação de Parsons, juntamente com a teoria Institucional e Neo-Institucional. Além disso, foi realizada uma breve discussão acerca dos conceitos de Racionalidade Instrumental e Substantiva. A partir das análises, frente à opção teórica delineada, pode perceber que na essência de tais atos, aparentemente irracionais, reside uma lógica calcada em avaliações e interpretações racionais, desde que devidamente analisadas a partir das especificidades de seus contextos. Dessa forma, ao rotular como irracional os altos custos assumidos pelas organizações, para a participação de seus funcionários em “eventos espetaculares” cultuados pelo mainstream, ou despesas com cursos de MBA´s, que muitas vezes não representam o retorno de conhecimento esperado, tais atos são plenamente racionais uma vez que visa consolidar sua legitimidade, elevar o consenso entre seus atores internos e externos, e assegurar a sobrevivência da organização.
ESTUDO DE CASO SOBRE AS CONDIÇÕES DE SEGURANÇA DOS FUNCIONÁRIOS DE BASE DA EMPRESA X NO MUNICÍPIO DE ANASTÁCIO/MS
Authors: Costa Osmar Souza , Lanzarini Ricardo
Published: June 2017

A presente pesquisa foi realizada em 2008 numa empresa revendedora de combustíveis para veículos automotores no município de Anastácio/MS. A metodologia é a pesquisa exploratória com estudo de caso e observação participante, objetivando conscientizar empresários e empregados sobre a importância da melhoria das condições de segurança do trabalho. Dentre os resultados, o risco de morte e contato com produtos químicos são problemas que trabalhadores da empresa investigada estão expostos diariamente na execução das tarefas. Para a adequação das atividades há necessidade da implantação de Normas de Segurança e Medicina do Trabalho, diminuindo os acidentes de trabalho e aumentando a produtividade.
Segmentos de consumidores de carne: O caso de pequenas cidades no Brasil
Authors: Lima-Filho Dario De Oliveira , Facioni Dejanira , Quevedo-Silva Filipe
Published: June 2017

Este trabalho teve como objetivo caracterizar os hábitos de consumo de carne e identificar segmentos de consumidores em pequenas cidades brasileiras. Para tanto, foi feito um estudo quantitativo-descritivo junto a 1200 famílias residentes em Mato Grosso do Sul. Os entrevistados consumem carne bovina mais de 7 vezes por semana; carne de frango é consumida 2,32 vezes por semana e este consumo não é maior em função do preço; carne suína é consumida menos de uma vez por semana e muitos não consomem por acreditar que faça mal a saúde. Foram identificados dois segmentos distintos em hábitos e características sócio-demográficas.
Relação entre o desempenho das organizações e o tempo de mandato (tenure) do Diretor-Presidente: um estudo em empresas brasileiras de capital aberto entre 1999 e 2008
Authors: Medeiros Júnior Roberto , Serra Fernando Ribeiro , Ferreira Manuel Portugal
Published: June 2017

Este artigo avalia a relação entre o tempo de mandato do Diretor-Presidente e o desempenho da organização. Testamos empiricamente duas hipóteses numa amostra de 34 firmas de grande porte negociadas na BOVESPA, entre 1999 e 2008. Para entender o desempenho das firmas, examinamos empresas que tiveram apenas um Diretor-Presidente durante o período. A análise permitiu concluir que (1) o tempo de mandato do Diretor-Presidente não está relacionado linearmente com o desempenho da organização, (2) o desempenho das organizações brasileiras perante o tempo de mandato dos seus Diretores-Presidentes tende a seguir uma curva em U-invertido, (3) mesmo em organizações familiares, o comportamento do desempenho assume o formato de U invertido. Isto indica que seria mais prudente realizar a sucessão do Diretor-Presidente quando a empresa inicia o declínio de desempenho.
SUBJETIVIDADE NO TRABALHO E MUDANÇA ORGANIZACIONAL: sustentação e reconstrução identitária do funcionário
Authors: Backes Airton Luiz
Published: June 2017

A discussão desenvolvida neste artigo, a partir de uma pesquisa descritivo-qualitativa, trata da vivência subjetiva do funcionário em uma empresa em importantes processos de mudanças organizacionais. O escopo da pesquisa está em verificar como a vivência subjetiva das mudanças organizacionais se reflete na sustentação e reconstrução da identidade do funcionário inserido na empresa em questão. As mudanças em curso na empresa pesquisada relacionam-se à mudança de controlador e de gestores, a inserção de novos valores e a inovações organizacionais. No plano teórico, o artigo apresenta aspectos relacionados ao simbólico na relação de trabalho, ao imaginário, à identidade e crise de identidade, a imaginário e ideologia na construção da identidade e identidade organizacional. Conclui-se que a vivência subjetiva das mudanças ocorridas na empresa implicou na desestabilização da identidade do funcionário, por meio do comprometimento do ambiente amistoso, da metaforização do ser humano como fruto do imaginário, do aumento da competitividade e do individualismo e da busca por qualificação profissional em razão da assimilação de uma nova ideologia.
GESTÃO DE PESSOAS POR COMPETÊNCIAS: ESTUDO EM UMA MINERADORA DE GRANDE PORTE
Authors: Bianco Mônica De Fatima , Colbari Antonia De Lourdes , Gonçalves Olenice Amorim
Published: June 2017

O objetivo é analisar a prática da Gestão de Pessoas por Competências (GPC) e suas interfaces com outros sistemas de gestão de pessoas (GP) em uma grande empresa mineradora brasileira. Analisaram-se aspectos do modelo GPC implantado no período de 2006 a 2009. Com enfoque qualitativo, a pesquisa foi desenvolvida com base na análise de documentos e de material obtido por meio de entrevistas. Os resultados indicam aspectos críticos no processo de implantação e consolidação desse sistema de gestão e em suas articulações com outros processos de GP; porém confirmam a GPC como abordagem que permite a negociação entre os atores organizacionais e a realização de feedbacks entre gestor e empregado.
SIGNIFICADO DO TRABALHO E ENVELHECIMENTO
Authors: Marra Adriana Ventola , Souza Mariana Mayumi Pereira de , Marques Antônio Luiz , Melo Marlene Catarina de Oliveira Lopes
Published: June 2017

Reconhece-se que os significados do trabalho podem ser distintos para os sujeitos em função de diversos fatores como profissão, faixa etária, contexto sócio-histórico. Foram investigados dezoito ex-executivos em processo de envelhecimento, escolhidos intencionalmente em função de sua idade e cargo que ocupavam. O processo de coleta de dados foi realizado por meio de entrevistas semi-estruturadas, analisadas pela Análise do Discurso. Constatou-se que as variadas formas de trabalho dão significado à vida, auxiliam no resgate de formas de status e poder e contribuem para a manutenção das identidades profissionais, além de minimizarem os efeitos sociais e físicos do envelhecimento.
ESTUDO SOBRE A UTILIZAÇÃO DE ATRIBUTOS DA IDENTIDADE CULTURAL BRASILEIRA COMO FONTE DE VANTAGEM COMPETITIVA NO SEGMENTO DE MODA
Authors: Sutter Mariana Bassi , Barakat Simone Ruchdi , Massaini Silvye Ane , Porto Maria Cecilia , Marinho Bernadete De Lourdes
Published: June 2017

Este estudo procurou investigar se a Brasilidade na moda representa fonte de vantagem competitiva no segmento de moda. Buscou-se também, verificar se o consumidor consegue identificar e hierarquizar os atributos da Brasilidade na moda. Levantou-se o referencial teórico relacionado a fontes de vantagem competitiva, consumidor de moda e Brasilidade na moda. Para tanto conduzir o estudo, realizou-se uma survey. Para a coleta de dados elaborou-se um questionário estruturado com questões fechadas e fotos de vestuários. A amostra totalizou 411 respondentes selecionados por conveniência. Os resultados permitiram detectar que a Brasilidade na moda pode ser uma fonte de vantagem competitiva.
RESTAURANTE COMO OPÇÃO DE LAZER PARA PESSOAS COM DEFICIÊNCIA VISUAL: INVESTIGANDO PREFERÊNCIAS
Authors: Faria Marina , Silva Jorge Ferreira
Published: June 2017

O objetivo do estudo foi determinar a importância relativa que as pessoas com deficiência visual dão aos atributos do serviço de restaurantes em momentos de lazer e a utilidade associada por tais consumidores aos níveis desses atributos. Para atingir esse objetivo, utilizou-se a técnica multivariada de análise conjunta. Os resultados apontaram cinco atributos como sendo os mais importantes para os pesquisados: a ambiência, o atendimento, o formato da mesa, o acesso ao garçom e o cardápio. O “acesso ao garçom” teve a maior importância relativa, e o atributo “atendimento” teve a menor.
“ABRAM-SE ÀS MULHERES TODAS AS PORTAS!”: CONVERSAS EM BLOGS DE MULHERES EM CARREIRA DE TI
Authors: Medeiros Cintia Rodrigues de O , Borges Jacquelaine Florindo
Published: June 2017

A emergência da nova economia, centrada, principalmente, nas tecnologias de informação (TI), causou impacto na sociedade em geral e no ambiente de trabalho, em particular. Neste artigo, analisamos se os sentidos produzidos nas relações de gênero entre os profissionais de TI implicam em transformação ou manutenção dos estereótipos femininos e masculinos presentes em modelos convencionais de organização. Para tanto, nós analisamos conversas em blogs que têm como foco “mulheres na carreira de TI”. Como resultados, mostramos os sentidos de gênero que reproduzem os estereótipos do trabalho feminino e masculino.
EXPERIÊNCIA INTERNACIONAL E PERFORMANCE EXPORTADORA: O CASO DE UMA EMPRESA DO SETOR MOVELEIRO PARANAENSE
Authors: Da Rocha Adilson Carlos , Rossetto Camargo Caroline , Marques Kneipp Jordana , Luciane Scherer Flavia , Maffini Gomes Clandia
Published: June 2017

O presente estudo teve como objetivoanalisar a experiência internacional e a performanceexportadora em uma empresa do setor moveleiro Paranaense. A pesquisacaracteriza-se como qualitativa e adotou como delineamento o estudo de caso.Para fins de coleta e análise dos dados adotou-se o modelo de Papadopoulos e Martín (2010) que visa analisar a experiênciainternacional e a performanceexportadora por meio das dimensões estratégica e econômica. As evidênciaspermitem concluir que o modo de entrada no mercado internacional adotado pelaempresa é a exportação do tipo indireta, na qual utiliza-se de intermediáriospara inserir seus produtos no mercado.
A MOUSE MODEL OF MAMMARY HYPERPLASIA INDUCED BY ORAL HORMONE ADMINISTRATION
Authors: Sun Li , Guo Dong-Hui , Liu Fei , Qian Liu , Jiang Ning , Sun Yun-Feng , Cai Li-Ping , Zheng Hong-Xin
Published: June 2017

Background: Mammary hyperplasia is one of the most common benign breast disorders. Although traditional Chinese medicine has a vast experience in the treatment of mammary hyperplasia, it is not accepted widely due to its unclear mechanism.

Methods and Materials: To address the mechanism, we developed a mouse model of mammary hyperplasia. We gave mice estradiol valerate tablets and progesterone capsules sequentially for one month by intragastric administration.

Results: Mice treated by this method had a series of pathological changes which are similar to those detected in women with mammary hyperplasia, including ectopic level of estradiol and progesterone in serum, hyperplasia of mammary glands and increased expression of ERα and PR.

Conclusion: This model will facilitate the mechanical study of traditional medicine on mammary hyperplasia.
EFFECT OF ASTRAGALOSIDE ON VITAMIN D-RECEPTOR EXPRESSION AFTER ENDOTHELIN-1-INDUCED CARDIOMYOCYTE INJURY
Authors: Yunzhi Chen , Jiaxu Chen , Jie Gao , Yihui Chai , Wen Li , Zhong Qin
Published: June 2017

Background: Astragaloside, which is one of the main components of Astragalus membranaceus, has been widely used in the treatment of congestive heart failure in China, and it can protect cardiomyocytes. Its mechanism of action remains unclear. Therefore, the present study was carried out to investigate the influence of astragaloside on rat cardiomyocytes stimulated with endothelin-1 (ET-1), and explored the underlying mechanism.

Materials and Methods: ET-1 was used to stimulate primary rat cardiomyocytes and establish a cardiomyocyte hypertrophy model. Different astragaloside doses were administered in combination with ET-1. Cardiomyocyte hypertrophy and apoptosis were examined using transmission electron microscopy (TEM) and flow cytometry, respectively. The molecular mechanism was explored by analyzing the mRNA of the vitamin D receptor (VDR), cytochrome P450 family 27 subfamily B member 1(CYP27B), cytochrome P450 family 24 subfamily A member 1(CYP24A) and renin mRNA levels by quantificational real-time polymerase chain reaction(qRT-PCR).

Results: Rat cardiomyocyte hypertrophy model was established successfully. Astragaloside administration significantly affected cell apoptosis and significantly inhibited ET-1-induced cardiomyocyte hypertrophy in a dose-dependent manner. Astragaloside treatment affected the expression of signaling molecules in the vitamin D axis.

Conclusion: Astragaloside inhibits ET-1-induced cardiomyocyte hypertrophy. This effect can be reversed by regulating the levels of the relevant factors in the vitamin D axis.
ANTITUMOR EFFECTS OF CHRYSANTHEMIN IN PC-3 HUMAN PROSTATE CANCER CELLS ARE MEDIATED VIA APOPTOSIS INDUCTION, CASPASE SIGNALLING PATHWAY AND LOSS OF MITOCHONDRIAL MEMBRANE POTENTIAL.
Authors: Sun De-Kang , Wang Lin , Zhang Peng
Published: June 2017

Background: The main objective of the current research work was to investigate the antitumor and apoptotic effects of

chrysanthemin in PC-3 human prostate cancer cells.

Materials and Methods: MTT assay was used to evaluate the effects of chrysanthemin on cell viability whereas flow

cytometry along with fluorescence microscopy were used to study apoptotic induction in these cells. Effects on caspase

activation were detected through western blot assay.

Results:Results showed that chrysanthemin inhibited cancer cell growth in PC-3 cancer cells in a time-dependent as well as

concentration-dependent manner. Chrysanthemin-treated cells at 10, 50 and 150 μM doses led to 34.2%, 56.7% and 69.1%

apoptosis in these cells respectively.The percentage of cells with depolarized mitochondria increased from 5.3% in

untreated control cells to 27.2%, 57.6% and 86.9% in cells treated with 10, 50 and 150 μM dose of chrysanthemin

respectively. Chrysanthemin also enhanced the activity of all three caspases viz., caspase-3, 8 and 9 in a dose-dependent

fashion.

Conclusions: The study concluded that chrysanthemin ledanticancer effects in PC-3 prostate cancer cells by inducing

apoptosis, activating caspasesignaling pathway and loss of mitochondrial membrane potential.
Research progress of CpG-DNA in regulation of immune system and signal pathway
Authors: Wang Yunpeng , Yang Xiaoming
Published: June 2017

 CpG-DNA is a DNA sequence with immunostimulatory function as the core of unmethylated CpG motif.It includes synthetic oligodeoxynucleotides (CpG-ODN) containing CpG motifs and genomic DNA of lower organisms such as bacteria, viruses, and invertebrates.CpG-DNA as a potential immunostimulatory factor can be recognized by the vertebrate natural immune system, rapid activation of natural immune response. When exposed to microbes, the release of CpG-DNA provides a "dangerous signal" to the body's immune system, triggering a protective immune response to remove foreign pathogens. CpG-DNA activated cell signaling mechanisms include endocytosis of CpG-DNA, specificity with Toll-like receptor 9 (TLR9) and a series of signal cascades that induce the expression of target genes and Feedback by various endogenous factors. This paper reviews the basic concepts of CpG-DNA, the characteristics of TLR9 receptors, the regulation of the immune system and its signaling pathways.
Cobertura de protección en salud y perfil de la población sin protección en México, 2000-2012
Authors: Pablo Gutiérrez Juan , Hernández-Ávila Mauricio
Published: June 2017

Objetivo.Analizar la cobertura actual de protección en salud en México, su tendencia desde el año 2000 hasta 2012, y el perfil de la población sin protección. Material y métodos. Análisis descriptivo del reporte del informante del hogar sobre protección en salud en las encuestas nacionales de salud 2000, 2006 y 2012. Resultados. Entre los años 2000 y 2012, la población mexicana sin protección en salud pasó de 57.6 a 21.4%. Esta reducción está dada principalmente por el crecimiento del Sistema de Protección Social en Salud, que se ha constituido en el principal asegurador en México, que ha cubierto a 38.5% de la población. La población sin cobertura se concentra entre los 15 y 30 años de edad. Conclusión. Los resultados muestran avances muy importantes respecto al incremento de la cobertura de salud. Sin embargo, resaltan también la complejidad de alcanzar el aseguramiento universal en un sistema fragmentado.
Sustainability: A Business Imperative, Not a Moral Sacrifice
Authors: Fattahi Behrooz
Published: June 2017

Management

In recent years, sustainability has emerged as perhaps the most critical imperative of this century. As our lives are being altered by advancing technology in ways that we never imagined just a few short years ago, our awareness and understanding of the complexities in utilization of the nature and the impact of the footprint that we leave behind must lead us to a fundamental shift in the way we manage our individual and professional lives.

The petroleum industry in concert with the rest of the world is finding that sustainability presents both risks and opportunities for its business, thus the need for incorporating sustainability as a business imperative and not a moral sacrifice.

Within the next 30 minutes as you are reading this article, our planet will be travelling roughly 40,000 miles in space around the sun, more than 8,000 babies will be born on this planet, and our oil and natural gas industry will supply nearly 2 million bbl of oil in response to the increasing demand for energy. The important question is how we can keep up with the many new and unique challenges posed by this fast-paced change.

The oil and gas industry faces a very challenging future. Energy demand continues to grow, while our mature fields are declining. Out of the 1.2 trillion bbl of proved oil reserves, roughly two-thirds are extremely challenging to develop and produce due to a variety of complicating problems such as depth and tight and thin formations; development and application of leading-edge technologies; and a multitude of environmental considerations and regulatory issues. Our task is to extend the life of the industry by improving the success of finding new discoveries in frontier and remote basins, increasing the ultimate recovery from existing fields, as well as the need to find ways to tap into unconventional resources. At the same time, we must intensify our focus on sustainability, which calls for meeting humanity’s needs without harming future generations. How are we to accomplish this goal of meeting energy demand in a sustainable way? Technology has always been the enabler for our industry to meet demand for the last 150 years. But now more than ever, the need for quick development and rapid deployment of technologies in the field is paramount.
Deepwater-Structure-Installation Challenges Offshore Australia
Authors: Carpenter Chris
Published: June 2017

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper OTC 26720, “Structure Deepwater-Installation Challenges—Northwest Shelf, Australia,” by Trent Broadway, SapuraAcergy, and Vincent Tachoires, Subsea 7, prepared for the 2016 Offshore Technology Conference Asia, Kuala Lumpur, 22–25 March. The paper has not been peer reviewed. Copyright 2016 Offshore Technology Conference. Reproduced by permission.

This paper provides an insight into the challenges encountered and overcome during installation of 20 subsea structures, some close to 1000 t in weight and in water depths of up to 1350 m, for the Gorgon project offshore Western Australia.

Introduction

The Gorgon project development comprises the Gorgon and Jansz-Io gas fields located off Australia’s northwest coast, in water depths of 200 and 1350 m, respectively. Ten structures were installed in 20 separate lifts, using the multipurpose heavy-lift and pipe-laying vessel Sapura 3000. Tight angular tolerances and low landing speeds were required to meet the structures’ design criteria.

All structures were loaded onto cargo barges and towed to site for installation. Liftoff and deployment through the splash zone were performed with the Sapura 3000 main crane. Depending on the size of the lift and the installation water depth, the structures were either deployed directly to the seabed using the crane (in the Gorgon field only) or transferred to a deepwater lowering system (DLS). Structure foundations were either skirted mud-mat types (deep water, soft-seabed locations) or suction piles, and were all fitted with fixed guideposts to assist with module-landing operations.

Installation Analysis

Subsea-structure foundations and modules are typically designed with landing-speed limitations; exceeding these might cause overstress within the structures. On the Gorgon project, the landing speeds were limited to less than 0.3 m/s.

Initial structure-landing analysis showed that the prescribed landing velocities would be difficult to achieve without further heave compensation because the sea-state limits would be too low to be realistically achievable given the prevailing weather conditions at the site. Because the main crane of the Sapura 3000 is not fitted with a heave-compensation system, a passive heave compensator (PHC) was introduced in the lift-rigging model to achieve better installation sea states.

Each of the 20 Gorgon and Jansz-Io structures required different PHC stiffness and damping because of their individual properties such as mass, rigging properties, perforated areas, and associated drag effects.

Lift-off analysis from the cargo barge was performed for the sea states identified by the governing installation step (landout). To achieve sea-state limitations, different PHC settings (stiffness and damping) were required for structural liftoff.
Sustainable Building Blocks for Cost-Effective Deepwater-Field Development
Authors: Carpenter Chris
Published: June 2017

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 181707, “Truly Sustainable Building Blocks for Deepwater-Field Development: Need for Strategy Redefinition in a Persistently Low-Oil-Price Scenario?,” by Francesco Beltrami, Energo Engineering, and Kevin Hansen, Granherne, prepared for the 2016 SPE Annual Technical Conference and Exhibition, Dubai, 26–28 September. The paper has not been peer reviewed.

To survive the current economic scenario, the deepwater industry needs to rethink the way projects are carried out. This paper reviews clusters of information that will be termed “building blocks” for deepwater-field-development planning, discussing how they are currently used and exploring more-affordable, but technically robust, alternatives.

Building Blocks

Advantages of Building Blocks. The use of conceptual “building blocks” during concept definition and concept selection is not new; they have been used in field-development planning for more than 3 decades. The field-development building blocks are a very versatile and powerful tool and are relatively simple to define and to use. They may be tailored to the case under investigation, providing a higher-level view or more-detailed insight, and can enable rapid generation of several development options. They also offer the possibility of producing simplified sketches representing field-development options (Fig. 1).

The key components of a future offshore field development are represented by predefined, project-specific building blocks that are combined in a methodical way (often automated) to generate multiple development options to be further ranked and screened. A typical building block is the type of host required in an offshore-field development. Multiple alternatives are possible, such as the floating production, storage, and offloading (FPSO) vessel; the semisubmersible; the spar; the tension-leg platform; and other fixed or floating platforms. 

Even a limited number of initial building blocks can generate a remarkable number of field-development options. To manage the potential complexity of the building-block approach, the quantity and type of building blocks to be used are generally defined in an early stage of the project. Specific building blocks may be added to ensure that project challenges are addressed properly.

Building blocks may be purely qualitative or may provide some quantitative information. In some cases, there might be multiple combinations of technical and nontechnical features for a single building block. In some geographical areas, the FPSO would necessarily have to be disconnectable; this requirement would affect the definition of the building blocks to be used.
Technology Focus: Multilateral/Extended-Reach Wells (May 2017)
Authors: Aadnoy Bernt
Published: June 2017

Technology Focus

In a previous issue of JPT, I read an interesting comment. A petroleum engineering department had visitors. One of them was asked to draw a well on the chalkboard, and she instinctively drew a horizontal well. She obviously considered horizontal wells as common. This illustrates that, during the last decade, wells such as horizontal wells, long-reach wells, and multilateral wells came to be considered mature technologies. Another aspect is that the technical level has increased significantly during this development. Currently, in well engineering, there are also many activities designed to stretch limits, improve processes, and make solutions more competitive economically.

The main objective of multilateral and extended-reach wells is improved field recovery. Multilateral wells expose more reservoir and improve reservoir drainage, whereas long-reach wells often increase drainage from existing platforms. Up to 80% of long horizontal wells may have inflow-control tools. The most common is the inflow-control-device orifice to control the water/oil contact, but more-advanced autonomous systems are being developed with more-precise control functions. A related group of tools includes water-stop mechanisms. Water production is a considerable challenge for the oil industry, from production, cost, and disposal perspectives. At present, there exist many useful completion technologies for inflow control and for workovers and stimulation purposes. New and improved functionalities open up for more-detailed reservoir analyses that ultimately will result in higher field recovery.

The featured papers all show improved solutions for constructing multilateral and long-reach wells. They show the dynamics of a continuous striving for improvements. These well types are very important tools in the search to maximize recovery from petroleum fields. 

Recommended additional reading at OnePetro: www.onepetro.org.

SPE 180445 Increasing Performance of Multilateral Wells Using Oil Fingerprinting by M.D. Jensen, ConocoPhillips, et al.

SPE 183422 Korchagina P-108: Breaking ERD Records Offshore North Caspian Sea—A Case Study by Vasily Zvyagin, Lukoil, et al.

SPE 184608 Reducing Well Costs and Extending Field Life With Intelligently Controlled Trilateral and Quadrilateral TAML Level-5 Multilaterals by Mark Glaser, Halliburton, et al.
Overcoming Challenges and Optimizing Liner Deployment in Long Laterals
Authors: Wilson Adam
Published: June 2017

This article, written by Special Publications Editor Adam Wilson, contains highlights of paper SPE 181288, “Overcoming Challenges, Improving Understanding, and Optimizing Liner Deployment in Long Laterals,” by Kim Daniel Mathisen, SPE, Tore Sørheim, SPE, and Tom Rune Koløy, SPE, Trican, and Neil Decker, SPE, Hess, prepared for the 2016 SPE Annual Technical Conference and Exhibition, Dubai, 26–28 September. The paper has not been peer reviewed.

A North Sea field development included installation of long 4½-in. completion liners in the horizontal reservoir sections of each well. To minimize overall risk, the operator planned to use managed-pressure drilling (MPD). Despite the expected positive effects of MPD, a strong understanding of the downhole dynamics during deployment of the lower-completion liner was needed. To address this challenge, the operator installed a newly developed work-string-dynamics logging tool directly above the liner-hanger-running tools.

Logging-Tool Technology Overview

The logging tool is a compact and robust memory-based surveillance tool made for drillpipe-conveyed well operations. It is designed, manufactured, and maintainde to be used without being a weak point in the string. The tool is equipped with an electronics package consisting of sensors, batteries, and memory.

The logging tool records

Axial loads (tension and compression)

Torque (left/right)

Pressures (absolute internal pressure, absolute external pressure, and differential pressure)

Temperature

The logging tool is typically shipped to the rigsite ready to be run in the well. The rig crew treats the tool as though it is a standard drillpipe pup joint, eliminating the need for dedicated field personnel and increased personnel on board. After starting logging, the tool can log for 36 days continuously, enabling multiple installations on a single battery package.

Logging Tool Description

The tool consists of three major components—a main body, housing, and a tool joint. The main body (inner mandrel) contains the electrical package with sensors. The housing protects the electrical package and is installed on the outside of the main body. The tool joint is mounted on the lower section on the main body. Axial loads on the tool are transferred through the main body and the tool joint; the housing is not exposed to axial loads. Torque is transferred through a robust spline system.

Results

The logging tool was placed directly above the liner-hanger-running tool in the installation string on seven liner deployments in this campaign. For all installations, both the primary logging tool and the backup were started at the base before shipment to the rigsite. This allowed for testing and field verification of the tool’s memory and battery lifetime. After completion-liner installation, the operator recovered the deployment string to surface with the logging-tool memory sub, which was then shipped back to the workshop onshore. The vendor then downloaded the data for analysis.
A Multiscale Time-Splitting Discrete Fracture Model of Nanoparticles Transport in Fractured Porous Media
Authors: El-Amin Mohamed F. , Kou Jisheng , Sun Shuyu
Published: June 2017

Recently, applications of nanoparticles have been considered in many branches of petroleum engineering, especially, enhanced oil recovery. The current paper is devoted to investigate the problem of nanoparticles transport in fractured porous media, numerically. We employed the discrete-fracture model (DFM) to represent the flow and transport in the fractured formations. The system of the governing equations consists of the mass conservation law, Darcy's law, nanoparticles concentration in water, deposited nanoparticles concentration on the pore-wall, and entrapped nanoparticles concentration in the pore-throat. The variation of porosity and permeability due to the nanoparticles deposition/entrapment on/in the pores is also considered. We employ the multiscale time-splitting strategy to control different time-step sizes for different physics, such as pressure and concentration. The cell-centered finite difference (CCFD) method is used for the spatial discretization. Numerical examples are provided to demonstrate the efficiency of the proposed multiscale time splitting approach.
Understanding the True Stimulated Reservoir Volume in Shale Reservoirs
Authors: Hussain Maaruf , Saad Bilal , Negara Ardiansyah , Sun Shuyu
Published: June 2017

Successful exploitation of shale reservoirs largely depends on the effectiveness of hydraulic fracturing stimulation program. Favorable results have been attributed to intersection and reactivation of pre-existing fractures by hydraulically-induced fractures that connect the wellbore to a larger fracture surface area within the reservoir rock volume. Thus, accurate estimation of the stimulated reservoir volume (SRV) becomes critical for the reservoir performance simulation and production analysis. Micro-seismic events (MS) have been commonly used as a proxy to map out the SRV geometry, which could be erroneous because not all MS events are related to hydraulic fracture propagation. The case studies discussed here utilized a fully 3-D simulation approach to estimate the SRV.

The simulation approach presented in this paper takes into account the real-time changes in the reservoir's geomechanics as a function of fluid pressures. It consists of four separate coupled modules: geomechanics, hydrodynamics, a geomechanical joint model for interfacial resolution, and an adaptive re-meshing. Reservoir stress condition, rock mechanical properties, and injected fluid pressure dictate how fracture elements could open or slide. Critical stress intensity factor was used as a fracture criterion governing the generation of new fractures or propagation of existing fractures and their directions. Simulations were run on a Cray XC-40 HPC system.

The results proved the approach of using MS data as a proxy for SRV to be significantly flawed. Many of the observed stimulated natural fractures were stress related and very few that were closer to the injection field were connected. The situation is worsened in a highly laminated shale reservoir as the hydraulic fracture propagation is significantly hampered. High contrast in the in-situ stresses related strike-slip developed thereby shortens the extent of SRV. However, far field natural fractures that were not connected to hydraulic fracture were observed being stimulated.

These results show the beginning of new understanding into the physical mechanisms responsible for greater disparity in stimulation results within the same shale reservoir and hence the SRV. Using the appropriate methodology, stimulation design can be controlled to optimize the responses of in-situ stresses and reservoir rock itself.
Investigation on microbial inactivation and urea decomposition in human urine during thermal storage
Authors: Zhou Xiaoqin , Li Yajie , Li Zifu , Xi Yue , Nazim Uddin Sayed Mohammad , Zhang Yang
Published: June 2017

The World Health Organization suggests storing human urine for at least 6 months at 20 °C prior to application as fertilizer to reduce the potential health risks from pathogenic organisms. Such a storage condition for human urine, however, not only requires a long period of time and large space but also ignores the risk of nitrogen losses. In this study, human urine underwent thermal treatment during storage to improve disinfection and to inhibit urea hydrolysis. Microbial indicators such as Escherichia coli and fecal coliforms and the concentration of ammonia/ammonium were investigated in urine samples that were stored at 60 °C and 70 °C. Both the inactivation of indicators and decomposition of urea improved under storage temperatures of 60 °C and 70 °C compared with storage under ambient temperature. Therefore, human urine is recommended to be stored at 70 °C for 7 days for hygienic and stabilization purposes. Under this storage condition, pH is maintained below 8.0 and ammonia/ammonium content is maintained at approximately 800 mg/L.
Reusing effluent of flue gas desulfurization wastewater treatment process as an economical calcium source for phosphorus removal
Authors: Dou Weixiao , Zhou Zhen , Ye Jiongjiong , Huang Rongwei , Jiang Lu-Man , Chen Guofeng , Fei Xiaoyun
Published: June 2017

Flue gas desulfurization (FGD) wastewater treatment by conventional neutralization, chemical precipitation and coagulation process removes most suspended solids and heavy metals, and provides an effluent rich in calcium, alkalinity and chloride, which obstructs its reclamation and reuse but is in favor of phosphorus (P) precipitation. The goals of this study were to investigate feasibility of reusing FGD effluent as a calcium source for P removal from P-rich wastewater. Results revealed that increasing the volumetric ratio between FGD effluent and P-rich wastewater achieved higher pH value and Ca/P ratio, and thus enhanced P removal efficiency to 94.3% at the ratio of 40%. X-ray diffraction and scanning electron microscope analysis of harvested precipitates showed that increasing pH from 8 to 10 induced the conversion of hydroxyapatite to tri-calcium phosphate, and then to whitlockite. This study demonstrated that for reusing FGD effluent for P removal was highly feasible, both technically and economically. This process not only saves the cost of precipitants for P removal, but also provides an economical alternative for current zero liquid discharge technology for FGD wastewater, which requires high energy consumption and capital costs.
Recent Advances in Obesity: The Role of Turmeric Tuber and Its Metabolites in the Prophylaxis and Therapeutical Strategies
Authors: Jarząb Agata , Kukula-Koch Wirginia
Published: June 2017

Background:

Obesity in the 21st century society became an important health problem,
alarming both the scientists and medicine doctors around the world. That is why, the search for new
drug candidates capable to reduce the body weight is of high concern.

Objective:

This contribution tends to collect current findings on the biochemistry of obesity and on the
application of plants and in particular turmeric tuber – a commonly used spice - as an anti-obesity agent.

Methods:

Following an introduction on the biochemical characteristics of obesity, the description of
Curcuma secondary metabolites, their pharmacological applications and a study on the plants’ regulatory
properties in obesity was summarized. Particular attention was paid to curcumin – the major metabolite
present in the extracts of Curcuma spp., which is known to exhibit a variety of pharmacological
actions. Also, the characteristics of some semisynthetic analogues of this ferulic acid derivative, characterized
by a higher polarity and better bioavailability will be discussed.

Results:

Numerous scientific papers treat on the influence of turmeric on weight loss. Additionally,
some of them describe its anti-inflammatory properties.

Conclusions:

This important spice tends to fight the 21st century plague, which is an excessive weight
gain, related to the development of metabolic syndrome, to the occurrence of cardiovascular problems
and diabetes, and, in consequence, leading to a significant shortening of life span. As herein proven, the
extracts of turmeric play an important role in the regulation of inflammatory reactions which are evoked
in the overweight patients, helping them reduce the excess body weight.
Os novos manuais escolares de Português do 7.º ano e a (re)construção do conhecimento gramatical. Conteúdos gramaticais e operações (meta)linguísticas
Authors: Silva António Carvalho da
Published: June 2017

Desde 2012/2013, os manuais escolares (ME) de Português foram objeto de alteração em função da publicação das Metas Curriculares de Português (Buescu et al., 2012), um novo documento orientador que originou mudanças nos discursos e nas práticas desses ME, ao nível de conteúdos e atividades, ou seja, na organização do conhecimento gramatical (aqui estudado) e dos outros domínios específicos do ensino e da aprendizagem do Português.De facto, as Metas Curriculares de Português (MCP) defendem que “O ensino dos conteúdos gramaticais deve ser realizado em estreita sintonia com atividades inerentes à consecução dos objetivos dos restantes domínios” (Buescu et al., 2012, p. 6). Tal visão implica a tendência de um ensino integrado da gramática, em que o conhecimento apoia as competências de compreensão e de expressão orais e escritas.Neste contexto, escolhendo para objeto de análise ME novos do 3.º Ciclo, este artigo tem por objetivos verificar a ocorrência de novas formas de abordagem dos conteúdos gramaticais e avaliar se as questões desse domínio são vistas como (re)construção do conhecimento escolar do Português.Espera-se, pois, que as conclusões ajudem a caracterizar algumas dimensões da natureza da gramática escolar, pela análise de conteúdos, atividades e métodos de ensino da gramática presentes em três manuais escolares de Português do 7.º ano