bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of veneering porcelain thickness and background shade on the shade match of zirconia-based restorations
Authors: Tabatabaian Farhad , Aflatoonian Khotan , Namdari Mahshid
Published: June 2019

Background. Effects of veneering porcelain thickness and background shade on the shade match of zirconia-based restorations are unclear. The aim of this study was to evaluate the impacts of veneering porcelain thickness and background shade on the shade match of zirconia-based restorations. Methods. Forty A2 shade veneered zirconia disk specimens (10 mm in diameter) were fabricated, with veneering porcelain thicknesses of 1.6, 1.8, 2.0 and 2.2 mm. Three backgrounds were made of A2 shade composite resin (A2), nickel-chromium alloy (NC) and amalgam (AM). The veneered zirconia specimens were placed on the backgrounds. CIELab values were measured with a spectrophotometer. ΔE values were measured to determine color differences between the specimens and the A2 VITA classical shade (target shade). ΔE values were compared with an acceptability threshold (ΔE=3.7). Repeated measures ANOVA, Bonferroni, and 1-sample t-test were used to analyze data (P<0.05). Results. Mean ΔE values ranged between 1.9 and 5.0. The veneering porcelain thickness, the background shade and their interaction affected the ΔE (P<0.0001). The minimum veneering porcelain thickness for the shade match was 2 mm for NC and 1.8 mm for AM. Conclusion. Veneering porcelain thickness and background shade affected the shade match of zirconia-based restorations. With dark-shaded backgrounds, the amount of veneering porcelain thickness needed for the shade match might be beyond acceptable clinical limits. Tooth-shaded backgrounds are esthetically advocated rather than dark-shaded backgrounds in zirconia-based restorations.
Patient-centered evaluation of alignment changes during the first stage of orthodontic treatment: A longitudinal observational study
Authors: Sohrabi Aydin , Tahamtan Shabnam , Rafighi Ali , Moslemzadeh Seyed Hossein , Seyedshariatdoost Sana
Published: June 2019

Background. The aim of this longitudinal observational study was to evaluate patients’ perceptions of alignment changes during the first stage of fixed orthodontic treatment. Methods. Ninety-three non-extraction patients (mean age: 17.6 years) who were scheduled to undergo fixed-appliance treatment in the first author's private office were included. Patients assessed the alignment of their teeth subjectively using visual analogue scale at the bonding session and four, eight and 12 weeks later. The amount of Little's irregularity index at each session was calculated on stone casts. Freidman test was used to compare the "alignment changes" between different intervals. Correlation coefficients were calculated using Spearman test between Little’s irregularity indices and alignment scores reported by the patients in each session. Results. No patients reported regression in alignment changes during three-month course of treatment. The final changes (from bonding session to the 12th-week visit) were smaller than the sum of the three intervals, which indicated that patients became more perceptive as the treatment progressed. Comparison of two scores reported for each session (in the same session and in the next session) revealed that patients could not recall their previous situation well. Patients do not perceive alignment changes in the same way as clinicians. Furthermore, patients who were 16 or older perceived smaller alignment changes during the first four-week period and smaller final alignment changes. Conclusion. To obtain better patient compliance and improve their motivation throughout orthodontic treatment, patientspecific measures should be undertaken, including reminding them about their initial conditions and highlighting the changes as the treatment progresses.
Efficacy of electromagnetic lithotriptor in the treatment of renal and upper ureteral stones
Authors: Mehrabi Sadrollah , Rasoli Esmat , Ghafarian Shirazi Hamidreza , Mehrabi Amir
Published: June 2019

Introduction: The innovation of outpatient extracorporeal shock wave lithotripsy (ESWL) has created a revolution in the treatment of urinary tract stones. Objectives: The aim of this study was to evaluate the success rate of electromagnetic lithotriptor, in the treatment of renal and upper ureteral stones. Patients and Methods: In this study, 84 patients aged over 10 years, with renal and upper ureteral stones less than 20 mm, were considered for ESWL. Patients were randomly assigned into two groups. In all patients, using ultrasound and fluoroscopy, stone was localized and using an electromagnetic machine by standard method, ESWL was performed with electromagnetic waves. ESWL started with 12 kV and was increased to18 kV, up to a maximum of 3500 shock waves. Two weeks later a kidney, ureter, and bladder (KUB) X-ray and ultrasonography was conducted and the success rate of lithotripsy according to the crushing of stones and decrease in stone size was measured and recorded. Results: In this study, 61.9% of patients were male. The mean age of patients was 46.62 ± 13.12 years. The mean size of stones in both groups was 13.4 ± 2.5 mm. Around 56.3% of patients had opaque stones and 43.8% had non-opaque stones. A total of 63.5% of patients received up to 3000 shock waves and 37.5% of patients received more than 3000 shock waves. Complete efficacy and clearance of renal and ureteral stones was observed in 54.8% and 59.1% of cases, respectively (P>0.05). Conclusion: This study showed a similarity in the success and efficacy of electromagnetic lithotriptor in the treatment of renal and upper ureteral stones. Additionally, the success rate of opaque and non-opaque stones have no significant differences, while stone size and proportion of shock waves will not increase the efficacy of the electromagnetic lithotriptor in crushing the stones.
Risk factors for delayed graft function in deceased donor kidney transplantation; a potential preventive role for intraoperative thymoglobulin
Authors: Naderi Neda , Alamdari Azam , Lessan-Pezeshki Mahboob , Dashti-Khavidaki Simin , Heydari-Seradj Mehran , Safdarpour Armin , Moradi Hamid , Mehdizadeh Ahmad , Khatami Mohammad-Reza
Published: June 2019

Introduction: Delayed graft function (DGF) is associated with significant adverse outcomes in deceased donor kidney transplantation (KT) including lower graft survival. However, risk factors and potential preventive strategies like intraoperative rabbit antithymocyte globulin (rATG; thymoglobulin) have not yet been fully evaluated. Objectives: The aim of this study was to investigate DGF risk factors and determine the association of intraoperative rATG with the risk of DGF in deceased donor kidney recipients. Patients and Methods: We retrospectively examined medical records of 163 first time deceased donor kidney transplant recipients at two major kidney transplant centers from 2014 to 2016. All the donors were standard heart-beating, brain death donors. Risk factors for DGF in recipients were evaluated using multivariate logistic regression analysis. Results: The mean recipients’ age was 43±13 years and the majority of participants were male (64%). The overall rate of DGF was 27%. Intraoperative rATG was significantly associated with a lower rate of DGF (adjusted odds ratio [AOR], 0.33, 95% CI, 0.11-0.95). Intraoperative transfusion (AOR, 3.7, 95% CI, 1.4-9.9) and diabetes mellitus (AOR, 3.7, 95% CI, 1.5-8.9) were significantly associated with higher risk of DGF. Conclusion: This study showed that intraoperative blood transfusion and diabetes mellitus were associated with increased risk of DGF. Meanwhile, administration of intraoperative rATG was associated with reduced odds ratio of DGF. Future studies are needed to evaluate the potential role of rATG in DGF-related renal outcomes.
‚Akzeleration der Prekarität: Analyse neuer Emanzipationsmodelle im kognitiven Kapitalismus mit Gilles Deleuze und Félix Guattari
Authors: Feichtinger Michael
Published: June 2019

Ausgehend von Gilles Deleuzes und Félix Guattaris Weiterentwicklung der marxistischen Theorie des Kapitalismus in Tausend Plateaus lege ich dar, wieso bestimmte Widerstandsstrategien im Paradigma des kognitiven Kapitalismus nicht fruchtbar sein können und worin ihre Schwächen liegen. Im Anschluss an diese Kritik stelle ich Anna Tsings anthropologische Studie über die Matsutakepflücker_innen als ein Emanzipationsmodell vor, welches Transitionsmöglichkeiten in eine post-kapitalistische Gesellschaft in hyper-prekären Arbeitsbedingungen verortet. Die Arbeiter_innen von Amazons Mechanical Turk werden hierbei als äquivalentes Prekariat im kognitiven Kapitalismus diskutiert, da auch sie ihre eigene Destruktionslinie erschaffen. Abschließend zeige ich, dass der linke Akzelerationismus gewissermaßen eine in der Theorie selbst kaum explizierte Radikalisierung von Tsings Appell des Prekär-Werdens darstellt. Zusammenfassend soll damit eine mögliche Perspektive aufgezeigt werden, wie diese neue und spekulative Emanzipationsstrategie wieder an ein Ende des Kapitalismus und eine post-kapitalistische Welt denken lassen.
Was ist die soziale Dimension in der Hochschulentwicklung? Ergebnisse einer Analyse hochschulpolitischer Strategiepapiere im österreichischen Hochschulsystem
Authors: Brandmayr Michael
Published: June 2019

Der Beitrag analysiert hochschulpolitische Strategiepapiere zur Frage, was der Begriff der sozialen Dimension im Diskurs um Hochschulpolitik in Österreich bedeutet. Es wird gefragt, welche Deutungen von Chancengerechtigkeit und Bildungsungleichheit mit ihm verbunden sind und welche Fördermaßnahmen damit begründet werden. Methodisch orientiert sich der Beitrag an der Wissenssoziologischen Diskursanalyse (Keller 2011), der Untersuchungszeitraum beträgt zehn Jahre.Die Ergebnisse der Analyse zeigen, dass der Begriff der sozialen Dimension mit der Bologna-Deklaration erstmals im Diskurs auftritt. Darin wurde Employability zum zentralen Bildungsziel des europäischen Hochschulraums. Es zeigt sich die Deutung, durch Individualisierung, Konkurrenz und Wettbewerb die Leistungspotentiale von Individuen effizient auszuschöpfen. Der Begriff der sozialen Dimension wird in diesem Kontext nicht mehr im Sinne der Kompensation gesellschaftlicher Ungleichheit, sondern als Leistungsgerechtigkeit verstanden.
Frank Sauer/Carlo Masala (Hrsg.) (2017): Handbuch Internationale Beziehungen
Authors: Höll Otmar
Published: June 2019

n/a
Emotions as Context: Do the Naturalistic Effects of Emotion Regulation Strategies Depend on the Regulated Emotion?
Authors: Southward Matthew W. , Heiy Jane E. , Cheavens Jennifer S.
Published: June 2019

Introduction: Researchers have examined how several contexts impact the effectiveness of emotion regulation strategies. However, few have considered the emotion-to-be-regulated as a context of interest. Specific emotions are important contexts because they may require particular responses to internal and external stimuli for optimal regulation.

Method: Ninety-two undergraduates completed 10 days of ecological momentary assessment, reporting their current mood, recent emotions, and emotion regulation strategies three times per day.

Results: The frequency with which certain emotion regulation strategies were used (i.e., acceptance, positive refocusing, reappraisal, problem-solving, and other-blame) differed by the specific emotion experienced. Acceptance and positive refocusing were associated with better mood regardless of emotion, while substance use was associated with worse mood regardless of emotion. Reappraisal was associated with better mood in response to anger than anxiety or sadness, while emotional suppression and other-blame were associated with worse mood in response to anger.

Discussion: These results suggest some emotion regulation strategies exhibit emotion-invariant effects while others depend on the emotion-to-be-regulated.
Anxiety Buffer Disruption: Relationship Threat, Death Anxiety, and Coping Appraisals Among Low and High Posttraumatic Stress Symptom Samples
Authors: Vail Kenneth E. , Courtney Emily P. , Goncy Elizabeth A. , Cornelius Talea , Edmondson Donald
Published: June 2019

Objective: Prior work suggests that people function effectively in the world, in part, by relying on sociocultural anxiety-buffer systems to protect against death anxiety. However, traumatic experiences may overwhelm and disrupt those systems, and this work tests whether posttraumatic stress symptoms reflect a vulnerability to death anxiety and risk of coping failure.

Method: Following posttraumatic stress screening (n = 4129), individuals with low (n = 187) and high (n = 186) posttraumatic stress symptoms engaged in either an anxiety-buffer stressor task (contemplating relationship problems) or control task. Participants subsequently reported death anxiety and made coping appraisals.

Results: Results supported four key hypotheses. Among individuals with low posttraumatic stress: (1) death anxiety was low under control conditions but moderately increased after contemplating relationship problems; and (2) perceived coping ability remained high in both conditions. However, among those with high posttraumatic stress: (3) death anxiety was exceptionally high in both the relationship problems prime and the control conditions—indicating anxiety buffer disruption; and (4) perceived coping ability was low in the control condition, and even lower after contemplating relationship problems.

Conclusions: These findings support the hypotheses and make novel contributions, in that prior research on the existential implications of PTSD have not considered that anxiety buffer disruption may be associated with failure to cope with new challenges after traumatic experiences. Future research should determine whether therapies can improve the core dimensions of functional worldviews, a sense of meaning and self-esteem, and whether such improvements result in improvements to perceived coping abilities.
Cyfip1Haploinsufficiency Does Not Alter GABAAReceptor δ-Subunit Expression and Tonic Inhibition in Dentate Gyrus PV+Interneurons and Granule Cells
Authors: Trent Simon , Hall Jeremy , Connelly William M. , Errington Adam C.
Published: June 2019

Copy number variation (CNV) at chromosomal region 15q11.2 is linked to increased risk of neurodevelopmental disorders including autism and schizophrenia. A significant gene at this locus is cytoplasmic fragile X mental retardation protein (FMRP) interacting protein 1 (CYFIP1). CYFIP1 protein interacts with FMRP, whose monogenic absence causes fragile X syndrome (FXS).Fmrpknock-out has been shown to reduce tonic GABAergic inhibition by interacting with the δ-subunit of the GABAAreceptor (GABAAR). Usingin situhybridization (ISH), qPCR, Western blotting techniques, and patch clamp electrophysiology in brain slices from aCyfip1haploinsufficient mouse, we examined δ-subunit mediated tonic inhibition in the dentate gyrus (DG). In wild-type (WT) mice, DG granule cells (DGGCs) responded to the δ-subunit-selective agonist THIP with significantly increased tonic currents. In heterozygous mice, no significant difference was observed in THIP-evoked currents in DGGCs. Phasic GABAergic inhibition in DGGC was also unaltered with no difference in properties of spontaneous IPSCs (sIPSCs). Additionally, we demonstrate that DG granule cell layer (GCL) parvalbumin-positive interneurons (PV+-INs) have functional δ-subunit-mediated tonic GABAergic currents which, unlike DGGC, are also modulated by the α1-selective drug zolpidem. Similar to DGGC, both IPSCs and THIP-evoked currents in PV+-INs were not different betweenCyfip1heterozygous and WT mice. Supporting our electrophysiological data, we found no significant change in hippocampal δ-subunit mRNA expression or protein level and no change in α1/α4-subunit mRNA expression. Thus,Cyfip1haploinsufficiency, mimicking human 15q11.2 microdeletion syndrome, does not alter hippocampal phasic or tonic GABAergic inhibition, substantially differing from theFmrpknock-out mouse model.
Spread of Measles in Europe and Implications for US Travelers
Authors: Angelo Kristina M. , Gastañaduy Paul A. , Walker Allison T. , Patel Manisha , Reef Susan , Lee C. Virginia , Nemhauser Jeffrey
Published: June 2019

From January 2018 to June 2018, World Health Organization (WHO) European Region countries reported >41 000 measles cases, including 37 deaths, a record high since the 1990s. Low vaccination coverage in previous years is the biggest contributing factor to the increase in cases. The Ukraine reported the majority of cases, but France, Georgia, Greece, Italy, the Russian Federation, and Serbia also reported high case counts. Europe is the most common travel destination worldwide and is widely perceived as being without substantial infectious disease risks. For this reason, travelers may not consider the relevance of a pretravel health consultation, including vaccination, in their predeparture plans. Measles is highly contagious, and the record number of measles cases in the WHO European Region not only puts unvaccinated and inadequately vaccinated travelers at risk but also increases the risk for nontraveling US residents who come into close contact with returned travelers who are ill. The US Centers for Disease Control and Prevention encourage US travelers to be aware of measles virus transmission in Europe and receive all recommended vaccinations, including for measles, before traveling abroad. Health care providers must maintain a high degree of suspicion for measles among travelers returning from Europe or people with close contact with international travelers who present with a febrile rash illness. The current WHO European Region outbreak should serve to remind health care providers to stay current with the epidemiology of highly transmissible diseases, such as measles, through media, WHO, and Centers for Disease Control and Prevention reports and encourage measles vaccination for international travelers.
Electronic Communication of the Health Record and Information With Pediatric Patients and Their Guardians
Authors: Webber Emily C. , Brick David , Scibilia James P. , Dehnel Peter ,   COUNCIL ON CLINICAL INFORMATION TECHNOLOGY,   COMMITTEE ON MEDICAL LIABILITY AND RISK MANAGEMENT,   SECTION ON TELEHEALTH CARE, Weinberg Stuart T. , Alexander Gregg M. , Beyer Eric L. , Hamling Alexander M. , Kirkendall Eric S. , Lighter Donald E. , Mann Ann M. , Morgan Stephen J. , Shelov Eric , Wright Jeffrey A. , Altman Robin L. , Bondi Steven A. , Fanaroff Jonathan M. , Narang Sandeep K. , Oken Richard L. , Rusher John W. , Santucci Karen A. , Scott Susan M. , Alexander Joshua J. , Bodnar Chelsea E.F. , Curfman Alison , Herendeen Neil E. , Kahn Joseph A. , McSwain Steven D.
Published: June 2019

Communication of health data has evolved rapidly with the widespread adoption of electronic health records (EHRs) and communication technology. What used to be sent to patients via paper mail, fax, or e-mail may now be accessed by patients via their EHRs, and patients may also communicate securely with their medical team via certified technology. Although EHR technologies have great potential, their most effective applications and uses for communication between pediatric and adolescent patients, guardians, and medical teams has not been realized. There are wide variations in available technologies, guiding policies, and practices; some physicians and patients are successful in using certified tools but others are forced to limit their patients’ access to e-health data and associated communication altogether. In general, pediatric and adolescent patients are less likely than adult patients to have electronic access and the ability to exchange health data. There are several reasons for these limitations, including inconsistent standards and recommendations regarding the recommended age for independent access, lack of routine EHR support for the ability to filter or proxy such access, and conflicting laws about patients’ and physicians’ rights to access EHRs and ability to communicate electronically. Effective, safe electronic exchange of health data requires active collaboration between physicians, patients, policy makers, and health information technology vendors. This policy statement addresses current best practices for these stakeholders and delineates the continued gaps and how to address them.
Instituições de longa permanência e centros dia para idosos em Camboriú e Balneário Camboriú-SC
Authors: Malheiro Alessandra Domingues , Feil Daiana Caroline Prestes , Nunes Paulo Roberto Ribeiro , Da Silva Maria Inês Conceição , Fernandes Flávia De Souza
Published: June 2019

AIM: The present study had as general objective to analyze the asylum and daycare institutions of the municipalities of Camboriú-SC and Balneário Camboriú-SC.METHOD: This is a descriptive study. Interviews were conducted with clinic leaders. Respondents answered open and closed questions about the modality and nature of the places, capacity of attendance, occupancy of vacancies, structure and general characteristics of the residents, among others.RESULTS: It has been found that most of the residents are over 70 and are women. It was found only one place that offered the modality home day and was private.CONCLUSION: As an offer of public power, the Secretariat of the Elderly Person in Balneário Camboriú was identified, offering more than 80 workshops aimed at the elderly with little or no dependency.
Association between functional balance and knee extensors strength in people with Parkinson’s disease
Authors: Clael Sacha , De Lima Filipe Dinato , Brandão Elaine Cristina da Silva , Rodrigues Jhonatan Conrado , Marcelino Camila Wells Damato , Pinheiro Rafaela Do Vale , Neto José Celi , Bezerra Lídia Mara Aguiar
Published: June 2019

Aims: The aim of this study is to verify if there is a correlation between functional balance and muscular strength of knee extensors in individuals with Parkinson’s disease.Methods: The sample consisted of 28 volunteers with Parkinson’s disease (age: 65.43±8.48 years, height: 1.68±0.10 cm, weight: 71.50±13.27 kg) classified on the modified Hoehn & Yahr scale. The Four Step Square Test and the isokinetic dynamometer were used to evaluate the dynamic balance and muscular strength of knee extensors, respectively.Results: The peak torque shows a moderate, negative and significant correlation with the Four Step Square Test (right knee: r=-0.471 and p=0.012; left knee: r=-0.444 and p=0.018).Conclusions: There is a negative, moderate and significant association between muscular strength of knee extensors and dynamic balance in Parkinson’s disease individuals.
Mito, olvido y manipulación de la historia de la masonería
Authors: Ferrer Benimeli José Antonio
Published: June 2019

Con ocasión de los 10 años de la revista REHMLAC+ se viene reflexionando a modo de balance sobre las investigaciones realizadas en estos últimos 40 años por parte de la historiografía y su alcance en el conocimiento real del fenómeno masónico. Aprovechando la reunión del Seminario Permanente Internacional de Historia de las Masonerías en Gijón, en febrero de 2019, se presenta una síntesis alrededor del mito, olvido y manipulación de la Historia de la Masonería con el deseo que algún día la realidad del pasado masónico ocupe el lugar que se apropiaron sus mitos y leyendas.
Masonería y política en Madrid (1900-1939)
Authors: Según-Alonso Manuel
Published: June 2019

El investigador Manuel Según Alonso ha defendido una tesis doctoral en historia, cuyo título es “Masonería y política en Madrid (1900-1939)” en la Universidad de Educación a Distancia (UNED) en España, el 2 de octubre de 2018, bajo la dirección de Juan Avilés Farré.
La Sociedad Teosófica en Costa Rica: Estudio histórico sobre la implantación, la cultura impresa, la proyección socio-política y la metafórica teosófica (1904-1930)
Authors: Rodríguez Dobles Esteban
Published: June 2019

El investigador Esteban Rodríguez-Dobles ha defendido una tesis de maestría académica en historia, cuyo título es La Sociedad Teosófica en Costa Rica: Estudio histórico sobre la implantación, la cultura impresa, la proyección socio-política y la metafórica teosófica (1904-1930) en la Universidad de Costa Rica en Costa Rica, el miércoles 10 de octubre de 2018.
Pastoralists – Farmers’ Conflicts in Jigawa State Nigeria: Causes, Repercussions and Solutions
Authors: Babagana M. , Yakubu Zakar. , Bello Harris Hamidan , Hussaini Abdulaziz
Published: June 2019

dimensions of most conflicts involving man since time immemorial. Of all resources, however, land has remained an overwhelming source of conflicts among various user groups as well as individuals at varying thresholds. In particular, conflicts between farmers and herdsmen in the use of agricultural land are becoming fiercer and increasingly widespread in Nigeria, largely due to ‘intensification and extensification’ of production activities that are necessitated by increasing human population (Gefu and Kolawole 2005; Fasona and Omojola 2005 cited in Adisa and Adekunle, 2010). The vital role of agriculture in the development of conflicts between pastoralists and farmers have been noted as an example of Low Intensity Conflict emanating from environmental degradation, resource scarcity, demographic and climate change (Shettima and Tar, 2008).
Two-Level Evolutionary Approach to Persistent Surveillance for Multiple Underwater Vehicles with Energy Constraints
Authors: Bychkov Igor , Kenzin Maksim , Maksimkin Nikolai
Published: June 2019

Currently, the coordinated use of autonomous underwater vehicles groups seems to be the most promising and ambitious technology to provide a solution to the whole range of oceanographic problems. Complex and large-scale underwater operations usually involve long stay activities of robotic groups under the limited vehicle’s battery capacity. In this context, available charging station within the operational area is required for long-term mission implementation. In order to ensure a high level of group performance capability, two following problems have to be handled simultaneously and accurately – to allocate all tasks between vehicles in the group and to determine the recharging order over the extended period of time. While doing this, it should be taken into account, that the real world underwater vehicle systems are partially self-contained and could be subjected to any malfunctions and unforeseen events.

The article is devoted to the suggested two-level dynamic mission planner based on the rendezvous point selection scheme. The idea is to divide a mission on a series of time-limited operating periods with the whole group rendezvous at the end of each period. The high-level planner’s objective here is to construct the recharging schedule for all vehicles in the group ensuring well-timed energy replenishment while preventing the simultaneous charging of a plenitude of robots. Based on this schedule, mission is decomposed to assign group rendezvous to each regrouping event (robot leaving the group for recharging or joining the group after recharging). This scheme of periodic rendezvous allows group to keep up its status regularly and to re-plan current strategy, if needed, almost on-the-fly. Low-level planner, in return, performs detailed group routing on the graph-like terrain for each operating period under vehicle’s technical restrictions and task’s spatiotemporal requirements. In this paper, we propose the evolutionary approach to decentralized implementation of both path planners using specialized heuristics, solution improvement techniques, and original chromosome-coding scheme. Both algorithm options for group mission planner are analyzed in the paper; the results of computational experiments are given.
Simulation of Motion Stability of Deformed Elongated Bodies Based on Variations of Angular Velocities in Roll
Authors: Romanova Irina
Published: June 2019

The class of moving objects, which are bodies of revolution, which for some reason have undergone irreversible deformations of the hull, is considered.

The immediacy of the problem being studied has to do both with the need to study the dynamics of such objects and the insufficiency of the studies already conducted, which are mainly focused on the study of the effects of aeroelasticity or mass asymmetry and do not affect the dynamics of bodies with irreversible deformations.

The problem of the motion stability of the considered objects, including the process of interaction of the longitudinal and lateral movements of the deformed body, is formulated. Particular attention is paid to the movement of the curved body with rotation about the roll and the identification of the presence of critical roll velocities. It is noted that for the case of passive movement there are three possible reasons for this interaction: aerodynamic, kinematic, inertial.

A theoretical approach has been developed that takes into account the specific features of the geometry of deformed bodies. The approach made it possible in practical studies to determine the allowable deformation levels and its relationship with the motion parameters of deformed bodies.

The stability analysis was carried out based on the stability criteria of the system solutions describing the body movement according to the Routh – Hurwitz criterion. The body parameters , which have a varying degree of influence on the stability of movement, are determined. In a more general case, the curve of the stability boundary for a given angular velocity in roll will have a more complex form than a simple hyperbola.

The possibility of obtaining a direct solution to a nonlinear to the determining parameters equation is also shown. It will make it possible to obtain the dependences of the critical heel velocities and stability ranges on these parameters.

Mathematical modeling based on the developed techniques, carried out for direct and curved bodies, showed that the body curvature has a significant effect on the displacement of the lines of derivative pitch moments in the angle of attack and the moment of sliding in the angle of slip relative to the limits of stability. The range of angular velocities for the roll is determined, in which a loss of stability is observed for the curved body. The effect of variations in the angular velocity and the relative change in the derivative of the yaw moment coefficient in the slip angle on the value of the determining factor from the stability conditions for the direct and curved bodies is analyzed. It is shown how the curvature of the body leads to a shift of the saddle point. The effect of a change in the Mach number on the determining coefficient of characteristic equations is analyzed.
Analysis of Linear and Angular Deviations of Implants Installed With a Tomographic-Guided Surgery Technique: A Prospective Cohort Study
Authors: de Oliveira Guilherme José Pimentel Lopes , de Souza Mattos Wagner , Albaricci Mariana , Marcantonio Élcio , Queiroz Thallita Pereira , Margonar Rogério
Published: June 2019

The aim of this study was to evaluate the linear and angular deviations of the implants installed by the computerized tomography (CT)–guided surgery technique. Eighteen patients who underwent implant insertion by means of CT-guided surgery participated in this study. Ten of these patients had a fully edentulous maxilla, and 8 had a fully edentulous mandible. The patients received a total of 115 implants, of which 81 implants were installed in the maxilla and 34 installed in the mandible. Tomographic guides were made for tomographic examination in both the upper and lower jaws. After the image acquisition, the virtual planning of the positioning of the implants was performed in relation to the previously made prosthesis. The measurement of the linear and angular deviations between the virtual planning and the final position of the implants was performed with the overlap of the planning and postoperative tomography. There were no differences in the linear and angular deviations of the implants installed in the maxilla and mandible. Compared with the coronal region, there was a trend of greater linear deviations in the apical regions of the implants and a greater tendency toward deviations in the posterior regions than in the anterior regions of both arches. The CT-guided surgery promoted the installation of implants with high accuracy and allowed the installation of straight pillars in all cases evaluated. The linear deviations were not different in the different regions of the mouth or in the different portions of the implants.
Introduction
Authors: Hill Crag , Pitre Leilya , Bickmore Steve
Published: June 2019

Introduction
On Anaya’s Bless Me, Ultima and Becoming a Lifelong Reader, and How I Nearly Blew It as a Teacher: An Extended Testimonio
Authors: René Saldaña, Jr.
Published: June 2019

This article, written in large part as a testimonio, argues that the use of culturally relevant texts with struggling, minoritized readers will increase their opportunity at literacy and academic success. The author recounts the story of when he discovered Cisneros’ The House On Mango Street (1991) that then led, unexpectedly, to Anaya’s Bless Me, Ultima (1972), two novels that caused him to fall in love with the reading act once again. The article also argues that educators must intentionally act on behalf of their struggling, minoritized readers by providing them numerous opportunities at discovering themselves in class-sanctioned literature by restructuring their required reading lists.
“If You Read, You’re Never Alone:” A Conversation with Dr. Judith A. Hayn and Dr. Jeffrey S. Kaplan
Authors: Terri Suico
Published: June 2019

An interview with Dr. Judith A. Hayn and Dr. Jeffrey S. Kaplan.
Results of Holter monitoring in patients with angina pectoris treated by combination of trimethazidine with fabomotisol in the area of former armed conflict
Authors: Shakhbieva Z. Yu. , Abdullaev A. A. , Islamova U. A. , Abdullaeva A. A.
Published: June 2019

Aim. To assess the effectiveness of trimetazidine and fabomotisol adding to standard treatment in patients with stable angina in the area of former armed conflict in point of improving of Holter monitoring parameters.

Material and methods. One hundred and twelve patients with stable angina of the II-III functional classes (FC) living in the area of former armed conflict were randomly divided into two groups. For 6 months 54 patients (control group) received standard treatment (isosorbide dinitrate 40 mg/day, metoprolole tartras 50-100 mg/day, acetylsalicylic acid 100 mg/day, simvastatin 40 mg/day). Fifty eight patients (study group) in addition to a standard treatment, took trimetazidine 70 mg/day and fabomotisol 30 mg/day. Initially and after 6 months they underwent Holter monitoring.

Results. In patients of the control group the number of episodes of silent myocardial ischemia was statistically significantly reduced (p<0,05). The duration of episodes of silent and manifest myocardial ischemia, ST segment depression >1 mm, and the number of patients with supraventricular and ventricular extrasystoles decreased not statistically significant (p>0,05). The number of episodes of manifest myocardial ischemia did not change. In the study group, the number of silent ischemia episodes, the duration of silent and manifest myocardial ischemia significantly decreased. ST segment depression and the frequency of ventricular extrasystoles were also decreased (p<0,05). At the same time, the changes in number of supraventricular extrasystoles was not statistically significant (p>0,05).  

Conclusion. Using a combination of trimetazidine with fabomotisol in comparison with standard treatment in patients with angina reduces the frequency of angina episodes, the duration of myocardial ischemia, ST segment depression, the frequency of supraventricular and ventricular extrasystoles.
Prognostic value of the cardiac fraction of fatty acid binding protein in patients with non-ST elevation acute coronary syndrome with concomitant type 2 diabetes
Authors: Berns S. A. , Zakharova V. A. , Shmidt V. S. , Lynev V. S. , Zverev К. V.
Published: June 2019

Aim. To study the association between a positive results of Heart-type fatty acid binding protein (h-FABP) test with the development of adverse outcomes during the year of observation in patients with non-ST elevation acute coronary syndrome (NSTE-ACS) depending on the type 2 diabetes mellitus (DM-2) presence.

Material and methods. The study included 153 patients with NSTEACS hospitalized in the department of emergency cardiology in the period from March 2014 to January 2017. In addition to the standard examination, all patients underwent a qualitative analysis on the h-FABP in venous blood.

 Results. Kaplan–Meier estimator demonstrated a significant probability of a combined end point in patients with positive h-FABP, both with and without DM-2. H-FABP also acts as a marker for the development of adverse outcomes during the year after NSTE-ACS. Patients with adverse outcomes and type 2 diabetes mellitus had the highest frequency (100%) of positive test reactions.

Conclusion. H-FABP positive test when admitted to hospital may be considered as a predictor of adverse long-term outcomes in patients with NSTE-ACS. That statistics is most significant for patients with DM-2.
Predictors of the development of non-cardiogenic syncopal conditions at a young age
Authors: Napalkov D. A. , Sokolova A. A. , Kondratyuk M. R. , Kudryavtseva A. A. , Krupenin P. M. , Savkov G. E. , Savkova O. D. , Yagofarova S. Yu. , Buchneva A. V. , Kwedhi J. M.
Published: June 2019

Aim. Syncopal condition in young people are a relatively frequent and poorly understood medical problem. Non-cardiogenic syncope is not sufficiently studied because often they are not raise fears among doctors or patients, and at the same time their causes are associated with many complex medical and diagnostic aspects. The aim of the presented work is to identify the most significant risk factors in the development of non-cardiogenic syncopal conditions, identify triggers and assess the relationship between these factors, the lifestyle and development of syncope.

Material and methods. The article presents the results of a descriptive research, including 1031 young people with a history of syncope episodes. The study took into account the presence of chronic diseases which could become a syncope trigger. External triggers (prolonged upright staying, stuffy room, and so on) were also determined.

Results. In a multifactor survey of students living in Russia and abroad, the more frequent occurrence of non-cardiogenic syncopal episodes in young girls compared with young men was found. The effect of longterm upright and oxygen corporal were most likely risk factors for syncope.

Conclusion. A significant correlation was found between the onset of reflex syncope and the presence of anemia and autonomic dysfunction syndrome. We proved the absence of a correlation between the level of daily load and the frequency of syncope conditions.
Development of a novel monoclonal antibody against chitinase-like protein YKL-39 applicable for immunohistochemistry
Authors: Gratchev A. N. , Samoilova D. V. , Kurochkin S. N. , Kovaleva O. V.
Published: June 2019

Introduction. Mammalian chitinase-like proteins are produced in the areas of inflammation and in tumors. Some members of chitinase-like proteins family are studied as potential biomarkers of tumors (glioma, prostate and ovary). YKL-39 also known as chitinase-3-like 2 (CHI3L2) is a secreted protein produced by chondrocytes. Its high expression is also found in synoviocytes, lung heart and macrophages.

The aim of this study was the development of highly specific monoclonal antibodies against human YKL-39.

Materials and methods. Using recombinant full-length human YKL-39 as immunogen using hybridoma technology we have generated monoclonal antibody 1B2G4, that specifically binds YKL-39 in ELISA.

Results and conclusion. Obtained antibody was successfully tested in Western blot, immunocytochemistry, immunofluorescence and immunohistochemistry on FFPE sections. It was shown that the antibody binds the full-length YKL-39 protein and does not interact with other chitinase-like proteins.
N-glycosidesindolo[2,3,-a]pyrrolo[3,4,-c]carbazole derivatives chemical structure influence on antitumor activity
Authors: Kiseleva M. P. , Pokrovsky V. S. , Borisova L. M. , Golubeva I. S. , Ektova L. V.
Published: June 2019

Introduction . The report considers the prospect of rational approach to the new anticancer agents creation based on indolocarbazole derivatives.

Objective . To conduct a comparative study of 12 domestic N-glycosides, indolo[2,3-a]pirrolo[2,3-a]carbazole derivatives in the course of “structure – activity” bond analysis.

Materials and methods . The investigation of influence of 12 carbohydrate – containing indolocarbazoles, synthesized in N. N. Blokhin Russian Cancer Research Center of the Ministry of Health of Russia, performed on models of solid transplantable mouse tumors: lung Lewis epidermoid carcinoma and B16 melanoma. The antitumor effect was assessed by Lewis epidermoid carcinoma and B16 melanoma tumor growth inhibition (TGI %) criterion.

Results . A variety of indolocarbazoles modifications allowed revealing the dependence of their antitumor properties on the structure of both, the aglycone and the glycoside residue. Imino-nitrogen interchange of atoms in upper heterocycle influences on indocarbazole derivatives antitumor activity change. During a comparative study of 12 N-glycosides indolocarbazole derivatives on lung Lewis epidermoid carcinoma and B16 melanoma models, 8 derivatives showed antitumor activity.

Conclusion . The formulated concepts on the modification features in indolocarbazole derivatives structure can be used for more active compounds creation with greater action selectivity.
The role of tumor stem cells in the development of drug resistance of melanoma
Authors: Chulkova S. V. , Markina I. G. , Chernysheva O. A. , Grishchenko N. V. , Antipova A. S. , Titov K. C. , Ryabchikov D. A. , Egorova A. V. , Naskhletashvili D. R. , Tupitsyn N. N.
Published: June 2019

Despite the fact that melanoma is a tumor of visual localization, mortality from skin melanoma remains one of the leading causes of mortality worldwide. Early metastasis of melanoma, even during the initial stages of the tumor process, indicates a high malignant potential of the tumor. Moreover, metastatic melanoma is resistant to current chemotherapy regimens, which is a significant problem today. Progression, resistance to drug therapy of skin melanoma is associated with a population of tumor stem cells, which are characterized by dysregulation of signaling pathways and aberrant phenotypes. The formation of tumor stem cells contributes to their microenvironment. Surface markers expressed by tumor stem cells include transporter proteins that mediate chemoresistance. The study of the microenvironment, the activity of the expressed antigenic determinants makes it possible to understand the processes of chemoresistance formation and to discover (develop) strategies for its overcoming. The article provides an analysis of the literature data on the significance of tumor stem cells in the development of drug resistance of melanoma.
The influence of multiphytoadaptogen on leukocyte infiltration in mice hepatocarcinomas
Authors: Karpova R. V. , Bocharov E. V. , Bocharova O. A. , Kazeev I. V. , Kucheryanu V. G. , Soloviev Yu. N.
Published: June 2019

The aim of this study was the morphological investigation of the CBA mice liver tissue at different stages of ontogenesis as well as during liquid form multifitoadaptogen therapeutic administration.

Materials and methods . The study objects are the liver samples of CBA male mice (subline CBA / LacY). Experimental animals received a 10 % solution of multifitoadaptogen from 6 months of age until natural death. Tissue samples were fixed in neutral buffered formalin and embedded in paraffin. Sections from paraffin blocks were stained with hematoxylin and eosin. The structure of the liver tumours was determined as well as the quantitаtive degree of leukocyte infiltration in the tumour tissue.

Results . The tumours morphologically structured as moderately differentiated trabecular hepatocarcinomas (at 8 months of age) and low differentiated trabecular-acinar hepatocarcinomas (aged 22 months) were revealed in CBA male mice. Higher lever of leukocyte infiltration in hepatocarcinomas of experimental animals was determined.

Conclusion . Leukocyte infiltration may be important for antitumour immune reaction as well as for reduction of the tumour formation incidence in high-cancer mice.
Dangerous Moments
Authors: WAMSTED JAY
Published: June 2019

The high-poverty urban school building is a prime environment for racial misunderstanding between teenagers and adults: most teachers are white and middle class, while most students are nonwhite and live near the poverty line. In this reflective essay, Jay Wamsted, a white teacher, examines the complicated nature of a teacher-student relationship in one such school. He uses a story of a hallway incident as a frame for examining his time spent teaching a young, black male student, and in doing so he demonstrates both successes and missteps, providing a window into the various interpersonal challenges facing the teacher in the high-poverty urban school.
Créditos
Authors: Guimarães Gustavo Cerqueira
Published: June 2019

Créditos do v. 4, n. 1, jan.-abr., 2019. Faculdade de Letras da UFMGDiretora: Profª Graciela Inés Ravetti de GómezVice-Diretora: Profª Sueli Maria Coelho EditoresElcio Loureiro CornelsenGustavo Cerqueira Guimarães Editores de seçãoDossiê – FutebóisSilvana Goellner (UFRGS) Entrevista e Poética  Gustavo Cerqueira Guimarães  Pareceristas desta ediçãoAndré Mendes Capraro, UFPRCésar Castilho, UEMGCleber Dias, UFMGChristina Fornaciari, UFVEduardo de Gomes, UFRJLuiz Carlos Ribeiro, UFPRMarcelino da Silva, UFMGMarcel Vejmelka, Univ. de MainzRaphael Rajão, FGVThiago Costa, UFMGYvonne Hendrich, Univ. de Mainz Projeto gráficoPeDRa LeTRa Coordenação Editorial, Preparação de Originais, Diagramação e Editoração eletrônicaGustavo Cerqueira Guimarães Editoração eletrônica em Redes sociaisErilma DesireéGabriel Canuto da Gama Imagem da capa do portalPablo Lobato (Brasil)Um a zero #2 (2012) Imagem da capa deste númeroDaniel Kfouri (Brasil)Sem título, 201?.
Contos de futebol escritos por mulheres: "Entre as quatro linhas" (2013), de Luiz Ruffato
Authors: Guimarães Gustavo Cerqueira
Published: June 2019

Resenha do livro Entre as quatro linhas: contos sobre futebol, organizado pelo escritor Luiz Ruffato.
"Sabe aquele gol que o Pelé não fez? Eu fiz!: a trajetória esportiva de Duda" (2018), de Silvana Goellner e Suellen Ramos
Authors: Costa Thiago Carlos
Published: June 2019

Resenha sobre o livro Sabe aquele gol que o Pelé não fez? Eu fiz!: a trajetória de Duda, de autoria das pesquisadoras Silvana Vilodre Goellner e Suellen dos Santos Ramos.
La competencia científica en los libros de texto de Educación Primaria
Authors: Laya Iglesias Paula , Martinez Losada Cristina
Published: June 2019

Este trabajo tiene como objetivo indagar en qué medida las actividades dirigidas al estudio del ser humano y la salud que proponen los libros de texto LOMCE de 6.º de Educación Primaria, correspondientes a tres editoriales de amplia implantación, promueven la adquisición de la competencia científica de los escolares. El análisis de las actividades (369 en total) se realiza teniendo en cuenta su tipología y el tipo de capacidades que dan ocasión de desarrollar. Respecto a ellas, además de los tres tipos definidos en PISA 2015 se consideran otras capacidades cognitivas presentes en las actividades. Los resultados muestran que  la mayoría son cuestiones puntuales de tipo académico, muy centradas en el uso de capacidades ligadas al conocimiento científico en sí, mientras que las directamente asociadas a la competencia científica son poco consideradas. Lo indicado demanda un cambio en los planteamientos de los textos, pues constituyen un elemento clave en la innovación de la enseñanza.