bluuebunny/crossref_metadata_2025 huggingface dataset:
A Bayesian Approach to Investigating Factors Influencing Polytechnic College Students’ Academic Achievement
Authors: Getahun Kidane A.
Published: January 2022

TVET plays a significant role in human resource development and, as a result, in a society’s progress and prosperity. The study is aiming at identifying the key factors influencing students’ academic success at polytechnic colleges. The study’s target population was regular Bahir Dar Polytechnic College students in the 2019/2020 academic year. Stratified random sampling was employed to conduct a cross-sectional survey of 536 participants. The author employed SPSS version 25 and WinBUGS 1.4 for quantitative data analysis. Bayesian logistic regression was used to model the factors that significantly influence TVET students’ academic achievement. Gender, age, family monthly income, study hours, stimulant use during the study, English language proficiency, EGSECE score, previous perceptions of TVET, teacher satisfaction, and field of study placement satisfaction were identified as factors that significantly influenced TVET students’ academic achievements. Being female, having a low family income, studying for a shorter period, using stimulants while studying, having a low English language proficiency, having a low EGSECE result, having a negative perception of TVET, and having low satisfaction with field of study were all linked to lower academic achievement in this study. According to the findings, students should spend more time in learning and consume fewer stimulants during their studies. The Ministry of Education should modify the TVET curriculum to aid students in improving their English language skills. Teachers in TVET should also receive ongoing capacity-building training. Finally, rather than imposing norms and limits (in terms of student achievement), TVET colleges should respect students’ free choice of training sector (department).
Reliability Analysis of Social Network Data Transmission in Wireless Sensor Network Topology
Authors: Wang Zhixue
Published: January 2022

In this paper, the reliability of data transmission in social networks is thoroughly studied and analyzed using wireless sensor network topology technology. This paper, based on the introduction of sensor network reliability analysis-related technology, combined with the characteristics, and needs of the sensor network itself, focuses on the study of the reliability analysis of the sensor network under the state of perturbation scheme. Based on the idea of making full use of data changes to respond to the sensor state, this paper takes the actual monitoring data of the wireless sensor network as the research object, selects the temporal correlation and spatial correlation of the measured environmental data as the reliability index by extracting the features of the wireless sensor network data, and proposes the Evidential reasoning rule- (ER-) based wireless sensor network data reliability assessment model based on Evidential reasoning rule (ER) is proposed. The data are mined, analyzed, and quantified from the perspective of content popularity, and the interest indicators of nodes on data under content popularity are analyzed to derive stable interest quantification values. Combined with the network properties, i.e., node autoassembly community, we analyze the data dissemination characteristics of social networks in wireless sensor network topology environment and derive the upper and lower bounds of data transmission capacity under node interest-driven and its variation on network performance. Social relationships among nodes affected by social attributes are considered; in turn, the data forwarding behavior of nodes is modeled using data transmission probability and data reception probability; finally, the data forwarding process is analyzed and a closed expression for the average end-to-end transmission capacity is derived in turn.
[Retracted] Research on Clothing Image Database Retrieval Algorithm Based on Wavelet Transform
Authors: Cui Xiaoyue
Published: January 2022

Aiming at the problems of low image data retrieval accuracy and slow retrieval speed in the existing image database retrieval algorithms, this paper designs a clothing image database retrieval algorithm based on wavelet transform. Firstly, it represents the color consistency vector of clothing image, reflects the composition and distribution of image color through color histogram, quantifies the visual features of clothing image, aggregates them into a fixed size representation vector, and uses the Fair Value (FV) model to complete the collection of clothing image data. Then, the size of the clothing image is adjusted by using the size transformation technology, and the clothing pattern is divided into four moments with the same size. On this basis, the clothing image is discretized with the help of Hu invariant moment to complete the preprocessing of clothing image data. Finally, the generating function of wavelet transform is determined, and a cluster of functions is obtained through translation and expansion. The wavelet filter is decomposed into basic modules, and then, the wavelet transform is studied step by step. The clothing image data are regarded as a signal, split, predicted, and updated and input into the wavelet model, and the retrieval research of clothing image database is completed. The experimental results show that the design of the retrieval algorithm is reasonable, the retrieval data accuracy is high, and the retrieval speed is fast.
Research on Fast Face Retrieval Optimization Algorithm Based on Fuzzy Clustering
Authors: Dong Xiajun , Huang Bin , Zhou Yuncai
Published: January 2022

Aiming at the problem of long retrieval time for massive face image databases under a given threshold, a fast retrieval algorithm for massive face images based on fuzzy clustering is proposed. The algorithm builds a deep convolutional neural network model. The model can be used to extract features from face photos to obtain a high-dimensional vector to represent the high-level semantic features of face photos. On this basis, the fuzzy clustering algorithm is used to perform fuzzy clustering on the feature vectors of the face database to construct a retrieval pedigree map. When the threshold is passed in for database retrieval of the target face photos, the pedigree map can be quickly retrieved. Experiments on the LFW face dataset and self-collected face dataset show that the model is better than the commonly used K-means model in face recognition accuracy, clustering effect, and retrieval speed and has certain commercial value.
UPLC-MS/MS Method for Simultaneous Determination of 14 Antimicrobials in Human Plasma and Cerebrospinal Fluid: Application to Therapeutic Drug Monitoring
Authors: Sun Huiting , Xing Han , Tian Xueke , Zhang Xiaojian , Yang Jing , Wang Peile
Published: January 2022

Pharmacokinetics/pharmacodynamics is the foundation for guiding the rational application of antibiotics in clinical practice, so it is necessary to establish quantitative methods for accurate drug concentration determination. This study aimed to develop a rapid and simple ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for simultaneous quantification of 14 antibiotics (amikacin, etimicin, ceftazidime, cefepime, cefoperazone, ceftriaxone, daptomycin, latamoxef, linezolid, meropenem, biapenem, ampicillin, norvancomycin, and vancomycin) in human plasma and cerebrospinal fluid. Antibiotics were chromatographically separated on a Waters ACQUITY UPLC BEH C18 column (2.1 mm × 50 mm, 1.7 μm) via gradient elution within 3 minutes and were monitored using positive ion fitted with multiple reaction monitoring. The lower limit of quantification was 0.05–2.0 μg·mL−1. The method was verified according to the FDA bioanalysis method validation guidelines, which showed excellent accuracy (from 86.75% to 110.85%) and precision (from 0.46% to 10.97%). At last, this method was successfully applied to therapeutic drug monitoring in 113 patients under antibiotics treatment.
Sesamol Attenuates Neuroinflammation by Regulating the AMPK/SIRT1/NF-κB Signaling Pathway after Spinal Cord Injury in Mice
Authors: Feng Xiaochu , Chen Xianghang , Zaeem Muhammad , Zhang Wanying , Song Liwan , Chen Lulu , Mubwandarikwa Joana , Chen Xiangxiang , Xiao Jian , Xie Ling , Ye Keyong
Published: January 2022

Inflammation is one of the crucial mechanisms mediating spinal cord injury (SCI) progress. Sesamol, a component of sesame oil, has anti-inflammatory activity, but its mechanism in SCI remains unclear. We investigated if the AMPK/SIRT1/NF-κB pathway participated in anti-inflammation of sesamol in SCI. Sesamol could inhibit neuronal apoptosis, reduce neuroinflammation, enhance M2 phenotype microglial polarization, and improved motor function recovery in mice after SCI. Furthermore, sesamol increased SIRT1 protein expression and p-AMPK/AMPK ratio, while it downregulated the p-p65/p65 ratio, indicating that sesamol treatment upregulated the AMPK/SIRT1 pathway and inhibited NF-κB activation. However, these effects were blocked by compound C which is a specific AMPK inhibitor. Together, the study suggests that sesamol is a potential drug for antineuroinflammation and improving locomotor functional recovery through regulation of the AMPK/SIRT1/NF-κB pathway in SCI.
Based on Optimization Research on the Evaluation System of English Teaching Quality Based on GA-BPNN Algorithm
Authors: Chen Yafei , Yu Zhenbang , Zhao Weihong
Published: January 2022

English teaching is an important part of basic teaching in our country, which has been deeply concerned by all aspects. Its teaching quality not only is related to the purpose of English teaching, but also has a far-reaching impact on students’ English learning. Therefore, the construction of English teaching quality evaluation system has become the focus of research. However, the traditional English teaching quality evaluation method has some problems; for example, the subjectivity of teaching evaluation is strong, the evaluation index is not comprehensive, and the evaluation results are distorted. Therefore, this paper studies the English teaching quality evaluation system based on optimized GA-BP neural network algorithm. On the basis of BP neural network algorithm evaluation simulation, GA algorithm is introduced for optimizing, and GA-BP neural network algorithm model is further optimized by GA adaptive degree variation and entropy method. The experimental results show that the optimized GA-BP neural network algorithm has faster convergence speed and smaller error. At the same time, the optimized GA-BP neural network algorithm evaluation model has better adaptability and stability, and its expected results are more in line with the ideal value. The results of English teaching quality evaluation are more scientific, showing higher value in the application of English teaching quality evaluation.
Safety and Efficacy of Combination Maintenance Therapy with Ixazomib and Lenalidomide in Patients with Posttransplant Myeloma
Authors: Patel Krina K. , Shah Jatin J. , Feng Lei , Lee Hans C. , Manasanch Elisabet M. , Olsem Jasper , Morphey Ashley , Huo Xiao Jiao , Thomas Sheeba K. , Bashir Qaiser , Qazilbash Muzaffar H. , Weber Donna M. , Orlowski Robert Z.
Published: January 2022

Purpose:

In this study, the addition of ixazomib to lenalidomide maintenance post-autologous stem cell transplant (ASCT) in 64 patients with newly diagnosed multiple myeloma was evaluated on the basis of the observed benefit of lenalidomide-only maintenance in prior studies.

Patients and Methods:

Patients were started on maintenance therapy with lenalidomide and ixazomib within 60–180 days of stem cell infusion.

Results:

Response rates deepened over time from baseline post-ASCT for 39 patients. The complete response (CR)/stringent CR rate was 43% and median overall survival was not reached with a median follow-up of 62 months (range, 25–82 months). Median PFS (mPFS) for all patients was 73 months and has not been reached for those with International Staging System (ISS) stage 1 disease. mPFS in 9 patients who had ISS stage 3 disease and 14 patients who had high-risk cytogenetics was 34 and 25 months, respectively. Twenty-two patients had progressive disease, while 19 patients continue to receive dual maintenance. The most common grade 3/4 adverse events included neutropenia, leukopenia, thrombocytopenia, lung infections, diarrhea, and maculopapular rash. Second primary malignancies occurred in 9 patients. Toxicity led to dose reductions in ixazomib and lenalidomide in 20 and 31 patients, respectively. Discontinuation of ixazomib due to toxicity occurred in 4 patients. Grade 1/2 neuropathy occurred in 22 patients and led to reduction or discontinuation of ixazomib in 2 patients.

Conclusions:

The addition of ixazomib to lenalidomide maintenance demonstrated a better than expected PFS compared with historical data using lenalidomide alone and was safe and tolerable.
An Unbiased Functional Genetics Screen Identifies Rare Activating ERBB4 Mutations
Authors: Chakroborty Deepankar , Ojala Veera K. , Knittle Anna M. , Drexler Jasmin , Tamirat Mahlet Z. , Ruzicka Regina , Bosch Karin , Woertl Johanna , Schmittner Susanne , Elo Laura L. , Johnson Mark S. , Kurppa Kari J. , Solca Flavio , Elenius Klaus
Published: January 2022

Despite the relatively high frequency of somatic ERBB4 mutations in various cancer types, only a few activating ERBB4 mutations have been characterized, primarily due to lack of mutational hotspots in the ERBB4 gene. Here, we utilized our previously published pipeline, an in vitro screen for activating mutations, to perform an unbiased functional screen to identify potential activating ERBB4 mutations from a randomly mutated ERBB4 expression library. Ten potentially activating ERBB4 mutations were identified and subjected to validation by functional and structural analyses. Two of the 10 ERBB4 mutants, E715K and R687K, demonstrated hyperactivity in all tested cell models and promoted cellular growth under two-dimensional and three-dimensional culture conditions. ERBB4 E715K also promoted tumor growth in in vivo Ba/F3 cell mouse allografts. Importantly, all tested ERBB4 mutants were sensitive to the pan-ERBB tyrosine kinase inhibitors afatinib, neratinib, and dacomitinib. Our data indicate that rare ERBB4 mutations are potential candidates for ERBB4-targeted therapy with pan-ERBB inhibitors.

Statement of Significance:

ERBB4 is a member of the ERBB family of oncogenes that is frequently mutated in different cancer types but the functional impact of its somatic mutations remains unknown. Here, we have analyzed the function of over 8,000 randomly mutated ERBB4 variants in an unbiased functional genetics screen. The data indicate the presence of rare activating ERBB4 mutations in cancer, with potential to be targeted with clinically approved pan-ERBB inhibitors.
Ocular TASER Probe Injury Managed with Primary Evisceration: Case Report
Authors: Sharabura Anna B. , Fong Joseph W. , Pemberton John D.
Published: January 2022

A 34-year-old male presented to the emergency department with a penetrating injury of the left globe and orbit from a Thomas A Swift’s Electric Rifle (TASER®) probe. The severity of the globe injury precluded primary closure of the globe; a primary evisceration was performed. In this article, we discuss not only the case in detail but also the TASER® rifle and the literature to support our decision in performing an evisceration rather than an enucleation, which historically has been taught to decrease the risk of sympathetic ophthalmia (SO) in the fellow eye. We are of the opinion, after reviewing the literature, that SO is not an overwhelming reason to choose enucleation over evisceration and that evisceration has an advantage over enucleation with regard to functional and cosmetic outcomes.
Sunitinib-Induced Adrenal Crisis in a Patient with Pre-Existing Immunotherapy-Related Hypopituitarism
Authors: Javaid Anadil , Mathai Jared , Song David , Brown Stephen
Published: January 2022

Sunitinib is a tyrosine kinase inhibitor that is frequently used in the treatment of metastatic renal cell carcinoma (mRCC). As a multikinase inhibitor, numerous off-target side effects of this medication are widely recognized. More recently, endocrine side effects, including hypoadrenalism, are becoming more apparent. We report a case in which a 71-year-old female experienced recurrent adrenal crises when managed with sunitinib for mRCC on a background of immune-related hypopituitarism and hypoadrenalism as a result of previous treatment with immunotherapy. Clinicians should be aware of this potential toxicity when using such medications and consider further investigation in the appropriate clinical setting.
A grid interconnected nested neutral-point clamped inverter with voltage synchronization using synchronous reference frame controller
Authors: Bogimi Sirisha
Published: January 2022

Nested neutral-point clamped multi level inverter with inter connection to grid through the synchronous reference frame (SRF) controller for synchronization of voltage to the grid is demonstrated. The system's main feature is that voltage stress in each inverter switching device is kept to a minimum, and redundant inverter switching states are utilised for neutral point and flying capacitor voltage balancing with sinusoidal pulse-width modulation (PWM) technique, synchronisation to grid voltages, and power injection with low harmonic generation. The inverter receives its input from a photovoltaic (PV) source that is coupled to DC-DC booster converters that are regulated by the maximum power point (MPP) tracking incremental conductance algorithm to maintain a constant dc voltage. The system is examined under various load conditions with MATLAB/Simulink model.
The Correlation of Use of Depo Medroxy Progesterone Acetate (DMPA) In-jections with Lipid Profile Levels in Rats
Authors: Suratiah Suratiah , Surinati Dewa Ayu , Yasa I Dewa Gede Putu Putra
Published: January 2022

Introduction: Family Planning is a national strategy of Indonesia government to manage the population growth. Depo Medroxyprogesterone Acetate (DMPA) is one of injectable contraceptives most widely used because it is simple and easy to obtain. However, it has various side effects causing imbalance of hormone estrogen, in turns to result in a decrease in HDL (High Density Lipoprotein) and an increase in LDL (Low Density Lipoprotein) which will result in an increase in total cholesterol. It will also affect changes in fat metabolism in human body due to hormonal influences. This results in dyslipidemia and atherosclerosis. Method: The method in this study is an experimental study with a pretest-posttest control group design. Results: The purpose of this study was to determine the relationship between duration of use of DMPA injections with lipid profile levels in mice. The data were analyzed by using the Paired t-test parametric test to compare between treatment groups. This study found that there were significant differences in HDL levels and total cholesterol levels between before and after administration of DMPA injections on the 14th and 35th days. There is a significant relationship between the duration of administration of DMPA injections with HDL levels and total cholesterol levels in mice. However, there was no difference in LDL levels and triglyceride levels between before and after administration of DMPA injection on day of 14 and day of 35, while, there was a significant difference between before and after the 35th day. There is no relationship between duration of administration of DMPA injections with LDL levels, while there is a relationship among mice triglycerides. Conclusions: Administration of DMPA injections for a long time lowers HDL.
O dispositivo da veste e a cesura entre ser e práxis: pensando um poder não fazer
Authors: Teixeira Eduardo Tergolina
Published: January 2022

O presente artigo tem por alvo discutir a questão da veste a partir da teoria de Giorgio Agamben. É exposta, em um primeiro momento, a concepção de potência, trazida pelo filósofo italiano dos ensinamentos aristotélicos, apresentando-se, em seguida, a constatação agambeniana sobre a cesura entre ser e práxis. As noções de dispositivo e de oikonomia são trazidas na sequência, a fim de pavimentar o terreno à análise do específico dispositivo veste-nudez, analisado em seguida. Expõem-se, então, algumas ideias críticas a esse respeito, finalizando-se o trabalho com o aporte da categoria da profanação. Resta como pano de fundo a análise da fratura entre a vida e forma, entre ser e sua obra, e a necessidade da preservação da característica por excelência da humanidade: a potência-de-não.
Gênero, emoções, afetos e cuidados: novos desafios para o campo da filosofia
Authors: Coelho Mateus Gustavo , Wolff Cristina Scheibe
Published: January 2022

Este trabalho pretende traçar uma relação entre a recente abertura acadêmica da Filosofia para os estudos feministas no Brasil e de como estes, em grande parte, têm sido responsáveis por colocar novos desafios ao ato de filosofar a partir das possibilidades trazidas pela discussão das interações entre a categoria gênero, com os estudos de afetos, emoções e cuidado. Ao trazer os afetos e emoções, ligados ao gênero, para a discussão nas Ciências Humanas e na Filosofia, os estudos feministas buscam estabelecer relações com partes da vida humana que durante séculos foram deixadas de lado no pensamento filosófico. Temas como a relevância das emoções, o cuidado com o outro e os afetos cada vez mais se fazem presentes dentro dos espaços de debate. Os estudos feministas não apenas ampliaram as temáticas possíveis dentro da academia, como também propiciaram diferentes possibilidades de escrita ao dar ênfase às subjetividades. Partindo de uma análise bibliográfica de autoras que pesquisam o papel dos afetos, emoções e cuidados, defendemos aqui que os estudos feministas ao trazerem estes temas como categorias de análise trazem consigo o próprio ato de espantar-se e de afetar-se com o mundo.
A noção de liberdade para Silvia Federici
Authors: Dias Maria Cristina Longo Cardoso
Published: January 2022

Busca-se, neste artigo, explicitar o conceito de liberdade para Silvia Federici. Será mostrado que esta noção, para a autora, significa a construção de lutas contra o modo de produção capitalista entendido como um sistema produtor e reprodutor de diversas formas de opressão como as de classe, raça e gênero, com vistas ao lucro. Neste sentido, torna-se necessário explicitar o processo de acumulação primitiva de capital como constituinte de antigas e atuais explorações para então mostrar as diversas lutas anticapitalistas que se formam.
Razão à sombra do sexismo: o feminino no pensamento de Sêneca
Authors: Bueno Taynam Santos Luz
Published: January 2022

Neste artigo será abordada a ambígua e, por vezes, contraditória representação das mulheres no pensamento do filósofo estoico Sêneca. Com isso, pretende-se demonstrar que a construção da postura misógina no âmbito da filosofia se dá, primeiramente, desde a antiguidade e, muitas vezes, de modo conflituoso com os próprios pressupostos e princípios professados pelas diversas correntes de pensamento. No caso específico deste texto, pretendemos demonstrar como Sêneca, declarado filósofo estoico, apresenta o gênero feminino de modo pejorativo e, como veremos, com discutível respaldo no conjunto dos princípios da filosofia do pórtico. Ao acompanhar as reflexões do pensador romano sobre o gênero feminino percebemos que há uma dupla apresentação das mulheres. Em algumas passagens, o filósofo as expõe como virtuosas e, portanto, dignas da atividade filosófica e da realização de ações corretas. Por outro lado, e na maior parte das vezes, o autor latino confere ao gênero feminino características que indicam limitações e podem prejudicar seu comportamento ético, mitigando assim o exercício pleno de sua racionalidade. Por muitas vezes, vemos Sêneca associar aos adjetivos femininos falhas morais e deficiências de caráter, ao passo que, aos adjetivos masculinos, o filósofo creditará ações virtuosas e ligadas à racionalidade. No entanto, como compreender tal ambiguidade em relação ao gênero feminino se, por princípio, o pensamento estoico afirma que a potencialidade de realização de ações virtuosas é garantida à humanidade, graças a sua participação na razão universal?
Marie de Gournay e Simone de Beauvoir: notas sobre memória e história
Authors: Blaud Clêmie Ferreira
Published: January 2022

A prática de evocar o nome de mulheres, personagens míticas ou reais, nos discursos filosóficos que tratam da emancipação feminina serve a dois propósitos principais: i. resgatar a memória das mulheres, com o propósito de reconstruir a história da filosofia, refutando os argumentos desfavoráveis às mulheres; ii. exemplificar os conceitos discutidos no texto com a ação ou pensamento de outras mulheres, muitas delas esquecidas na história da filosofia. O estudo das semelhanças e diferenças no modo como os nomes de mulheres são mobilizados produz novas reflexões sobre a memória e a história da filosofia. Este artigo investiga essas questões em dois textos, sendo um do século XVII, Égalité des hommes et des femmes, escrito por Marie de Gournay; e o outro do século XX, o capítulo intitulado "História" da obra O segundo sexo de Simone de Beauvoir.
O feminismo espinosano de Marilena Chaui: Espinosa contra as Amazonas ou a hipótese contrária
Authors: Xavier Henrique Piccinato
Published: January 2022

A partir de um dos primeiros textos publicados por Marilena Chaui, o “Terceira margem. Notas para um rodapé selvagem” de 1976, que inaugura a sua reflexão acerca do estatuto político das mulheres e, ao mesmo tempo, amadurece suas primeiras ideias acerca do que viria constituir o Nervura do real (sua principal obra sobre Espinosa), o nosso ensaio se pergunta acerca da possibilidade de um feminismo espinosano operando na obra de Chaui. Para tanto, procuramos dar conta de como o referido texto de 1976 aborda a aparente hipótese da rejeição da participação das mulheres na democracia no Tratado político de 1677 de Espinosa, sendo esta rejeição um problema enfrentado pelas principais feministas contemporâneas que recorrem à filosofia de Espinosa para fundamentar suas ideias e lutas. Levando em conta esta última consideração e o fato de que no Brasil ainda sejam raras as aproximações entre feminismo e Espinosa (algo diferente do que acontece internacionalmente), o nosso ensaio apresenta um apêndice contendo o mapeamento das principais obras, autoras e linhas do que contemporaneamente vem a ser chamado de feminismo espinosano.
A intelectualidade negra e a produção científica: um olhar decolonial
Authors: Matta Betânia de Assis Reis , Machado Rita de Cássia Fraga
Published: January 2022

Este artigo discute o papel feminino na produção de conhecimentos científicos a partir da perspectiva decolonial. Possui como linha de análise a educação libertadora e reflete sobre os discursos sociais contemporâneos pautados em um modelo de pensamento colonialista. Para esse pensamento colonialista, a questão de gênero ainda é muito relevante. A importância deste tema se justifica pela necessidade de compreender os aspectos procedentes da mentalidade colonizadora, que silenciou, censurou e desvalorizou o conhecimento produzido pelas mulheres ao longo da história. Por isso, espaços democráticos de debates devem ser criados para que os grupos que não foram visibilizados durante muito tempo por essa sociedade patriarcal, machista e desigual possam ser ouvidos e acolhidos. Para tanto, a metodologia utilizada foi a pesquisa bibliográfica, tendo como corpus de análise artigos científicos e livros. Os materiais pesquisados fazem referência aos estudos decoloniais e ao legado do Movimento Feminista Negro.
Não ando só! Homenagem às professoras do Departamento de Filosofia da USP
Authors: Lacerda Tessa Moura
Published: January 2022

Neste relato, tenho a difícil e honrosa tarefa de me colocar ao lado de grandes mulheres, professoras do Departamento de Filosofia da Universidade de São Paulo, recuperando muito brevemente aspectos de minha trajetória pessoal.
Plebe, política e acontecimento, de Alain Brossat
Authors: Benedykt Breno , Pelegrini Maurício , Silva Renan Ferreira da
Published: January 2022

Apresentação da tradução e tradução do texto de Alain Brossat.
Calendários de mulheres nuas, batons e loções afrodisíacas: artefatos simbólicos e arquétipos ligados ao gênero, desejo e processos de dominação
Authors: Brière Manuela Triani Gomes de Knegt
Published: January 2022

O presente artigo trata de três obras de arte produzidas nas décadas de 1960 e 1970 por Lygia Pape, Wanda Pimentel e Maria Eugenia Chellet. Todas as três colocam em cena o corpo de mulheres ambientado em distintas situações onde discursos normativos da sexualidade e processos de dominação são evidenciados. As principais fontes de pesquisa para este artigo foram depoimentos das artistas, entrevistas, textos de exposições, além de uma literatura dirigida à sexualidade feminina e aos mecanismos de estabelecimento de relações de dominação.
Tecido adiposo marrom em adultos como alvo de estudo no desenvolvimento de novas terapias para o manejo e tratamento da obesidade: uma revisão integrativa
Authors: Schnaider Juliana Moreira , Borges Beatriz Essenfelder
Published: January 2022

Introdução: O tecido adiposo marrom foi inicialmente evidenciado em animais e posteriormente em humanos tendo sua função principal a termorregulação. A partir disso, pesquisam-se possibilidades desse tecido auxiliar no controle de massa corporal, a fim de alcançar novas perspectivas no tratamento da obesidade, uma pandemia da atualidade. Objetivo: Compreender o tecido adiposo marrom e abordar hipóteses que caracterizam a contribuição deste no tratamento da obesidade e de suas comorbidades. Materiais e Métodos: Realizou-se uma revisão integrativa na qual foram usados os descritores brown adipose tissue, obesity, thermogenesis, uncoupling protein 1, UCP nas bases de dados PubMed® e Google Acadêmico. Ao todo, 19 artigos e 4 livros referentes às ciências Histologia, Biologia Celular e Fisiologia embasam a revisão. Discussão: O tecido adiposo está presente por todo corpo humano e ocasiona efeitos significantes na fisiologia e patologia do organismo. Os adipócitos que o compõem apresentam diferenças histológicas, biocelulares e de distribuição e subdividem-se em uniloculares e multiloculares. As células multiloculares formam a gordura marrom que é capaz de regular o gasto energético por meio da termogênese adaptativa via proteína desacopladora (UCP). Com esses conhecimentos, buscam-se relações entre o tecido adiposo composto pelas células unicelulares, o qual é o responsável pelo desenvolvimento da obesidade, e o tecido adiposo marrom. Nesse âmbito, dentre as possibilidades de estudo há fatores que influenciam a expressão tecidual da proteína desacopladora e aumentam a termogênese química, há o controle do balanço energético e, ainda, a capacidade de adipócitos marrons de sequestrarem o succinato (flavoproteína que exerce controle agudo sobre a termogênese) da circulação. Conclusão: Foi possível compreender a multifuncionalidade e as características físicas e químicas do tecido adiposo marrom e reconheceu-se esse tecido como um dos potenciais alvos de estudo dada a singularidade epidemiológica da obesidade e seu histórico de tratamentos.
Estranhamentos e surpresas: hábitos alimentares no conteúdo de ensino de português língua estrangeira
Authors: Nélo Maria José , Sellan Aparecida Regina Borges
Published: January 2022

Este artigo discute estratégias de ensino tendo por focalização as necessidades essenciais de estudantes que visam aprender o português como língua estrangeira. Esses estudantes esperam obter conhecimentos linguísticos, enciclopédicos, sociointerativos plausíveis para o uso no cotidiano deles, por exemplo, designar, transformar os alimentos consumidos pelos nativos (maranhenses). Esses conteúdos sobre alimentos são, neste estudo, entendidos como um dado cultural e, para os falantes de outras línguas, uma oportunidade de compreender nosso sistema linguístico e de relação sociocultural para inserção no novo contexto. Os resultados demonstram que os falantes estrangeiros observados manifestaram menos estranhamentos linguísticos do que culturais, razão pela qual consideramos que significados culturais devem fazer parte dos conteúdos selecionados para o ensino de português língua estrangeira (PLE).
Preconceito e discriminação entre alunos do ensino médio
Authors: Kohatsu Lineu Norio , Ferreira Leoncio Tavares , Acosta Diana Ureña , Patty Neusa Dayane Mendoza , Salgado Júlia Demétrio
Published: January 2022

Neste artigo, são apresentados os resultados de uma pesquisa realizada no âmbito do Programa de Pré-Iniciação Científica da Universidade de São Paulo. A pesquisa teve por objetivo investigar as vivências e percepções de alunos de ensino médio sobre discriminação na escola e buscou comparar as respostas dos alunos de diferentes nacionalidades. A coleta de dados foi realizada em uma escola estadual no município de São Paulo, por meio de um questionário disponibilizado em formulário online, autopreenchido, além de entrevistas com dois alunos de origem boliviana. Constatou-se que as manifestações de discriminação na escola não são frequentes, sendo a xenofobia a forma mais mencionada pelos participantes. Foram constatadas também diferenças nas percepções de brasileiros/as, filhos/as de bolivianos e bolivianos/as.
Mitigating Initial Orthostatic Hypotension: Mechanistic Roles of Muscle Contraction Versus Sympathetic Activation
Authors: Sheikh Nasia A. , Phillips Aaron A. , Ranada Shaun , Lloyd Matthew , Kogut Karolina , Bourne Kate M. , Jorge Juliana G. , Lei Lucy Y. , Sheldon Robert S. , Exner Derek V. , Runte Mary , Raj Satish R.
Published: January 2022

Background:

Initial orthostatic hypotension (IOH) is defined by a large drop in blood pressure (BP) within 15 s of standing. IOH often presents during an active stand, but not with a passive tilt, suggesting that a muscle activation reflex involving lower body muscles plays an important role. To our knowledge, there is no literature exploring how sympathetic activation affects IOH. We hypothesized involuntary muscle contractions before standing would significantly reduce the drop in BP seen in IOH while increasing sympathetic activity would not.

Methods:

Study participants performed 4 sit-to-stand maneuvers including a mental stress test (serial 7 mental arithmetic stress test), cold pressor test, electrical stimulation, and no intervention. Continuous heart rate and beat-to-beat BP were measured. Cardiac output and systemic vascular resistance were estimated from these waveforms. Data are presented as mean±SD.

Results:

A total of 23 female IOH participants (31±8 years) completed the study. The drops in systolic BP following the serial 7 mental arithmetic stress test (−26±12 mm Hg;
P
=0.004), cold pressor test (−20±15 mm Hg;
P
<0.001), and electrical stimulation (−28±12 mm Hg;
P
=0.01) were significantly reduced compared with no intervention (−34±11 mm Hg). The drops in systemic vascular resistance following the serial 7 mental arithmetic stress test (−391±206 dyne×s/cm
5
;
P
=0.006) and cold pressor test (−386±179 dyne×s/cm
5
;
P
=0.011) were significantly reduced compared with no intervention (−488±173 dyne×s/cm
5
). Cardiac output was significantly increased upon standing (7±2 L/min) compared with during the sit (6±1 L/min;
P
<0.001) for electrical stimulation.

Conclusion:

Sympathetic activation mitigates the BP response in IOH, while involuntary muscle contraction mitigates the BP response and reduces symptoms. Active muscle contractions may induce both of these mechanisms of action in their pretreatment of IOH.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT03970551.
The Dissolution of the Soviet Union
Authors: Kramer Mark
Published: January 2022

In late December 1991—some 74 years after the Bolsheviks had taken power in Russia under the leadership of Vladimir Lenin—the Soviet Communist regime and the Soviet state itself ceased to exist. The demise of the Soviet Union occurred less than seven years after Mikhail Gorbachev became the leader of the Soviet Communist Party. Soon after taking office in March 1985, Gorbachev had launched a series of drastic political and economic changes that he hoped would improve and strengthen the Communist system and bolster the country's superpower status. But in the end, far from strengthening Communism, Gorbachev's policies of perestroika (restructuring) and glasnost (official openness) led inadvertently to the collapse of the Soviet regime and the unraveling of the Soviet state. This article analyzes the breakup of the Soviet Union, explaining why that outcome, which had seemed so unlikely at the outset, occurred in such a short period of time.
The historical relics in Chongqing Natural History Museum: An annotated checklist of original materials for 37 names of Chinese seed plants
Authors: CHEN FENG , HE HAI
Published: January 2022

A catalogue of type specimens deposited at the herbarium of Chongqing Natural History Museum (CQNM) is carried out. A total of 62 specimens belonging to 56 gatherings concerning 37 valid published names in 23 families of Chinese seed plants are documented as original materials. They include seven isotypes, 21 syntypes, of which 16 of them are isolectotypes and 34 paratypes. A checklist of the 37 names is presented with annotations on the typification, authorship citation, type localities and other taxonomic issues. Eight names were lectotypified, and one name’s second-step lectotype is proposed. Additionally, Distylium lanceolatum Chun, which is invalid pending for further study, and which has long been treated as a synonym of D. dunnianum H.Lév., is listed after the 37 names.
Sedum dormiens (Crassulaceae, Sempervivoideae, Sedeae): a new species from the Sierra de Manantlán, Mexico
Authors: CUEVAS-GUZMÁN RAMÓN , PÉREZ-CALIX EMMANUEL , CARRILLO-REYES PABLO
Published: January 2022

Sedum dormiens (Crassulaceae) from the Sierra de Manantlán in Jalisco, Mexico, is described. The distinctive characters of the species are its chamaephytic nature, capillary roots, formation of large colonies, tetramerous flowers with white petals, dormant terminal and lateral buds in the mother plant and connate fruits of ½–¾ its length. The habitat and morphology of the species is illustrated and its relationships with close species presented. Its conservation status was categorized as Endangered (EN).
A third species of Parakermania Vandel, 1973 (Isopoda: Oniscidea: Armadillidae) from China
Authors: HONG XINKAI , WANG YUTAO , LI WEICHUN
Published: January 2022

Parakermania longa sp. nov., the third species of the woodlouse genus Parakermania Vandel, 1973 is described and illustrated from China. The new species differs from the other two congeners in having a different number of dorsal tubercles, and two well-developed ornamentations on the outer sides of the sixth pereonite going beyond the apex of telson. A key to Parakermania species is provided.
4. Terminological Horizons
Authors: Potter Thea
Published: January 2022

The problem of determinate definition was assumed by Hegel and Heidegger but has been the problem for philosophy ever since Aristotle defined finding the ‘essence’ or being of something as the task of philosophy. The problem is always a terminological one, but we have inherited it also as a problem of translation. This problem belongs to the horos, the question of definition and the necessary overlap between words in both metonymy and metaphor. Chapter Four (‘Terminological Horizons’) focuses upon the translation of horos as ‘term,’ ‘definition,’ ‘determination,’ a sense of the word that is outlined by Aristotle in his Topics and Categories where he provides a definition of horos as the word that means ‘what it is to be.’ If horos (here ‘definition’) is a word that signifies the being of a thing, is it itself retained within the definition of a word even if in the form of a trace of this lithic term? Although the horos as ‘definition’ remains essential within the tradition of Western philosophy, its material presence has been confounded in the attempts at absolute conceptualisation and transcendental reasoning. That said, we do get a brief and telling glimpse of it in the preface to Hegel’s Phenomenology. Its echo remains also in the work of Heidegger, inherited from Husserl, as that which frames our position in the world, as the ‘horizon,’ verbal cognate of the horos.
6. Geophilia Entombed or the Boundary of a Woman’s Mind
Authors: Potter Thea
Published: January 2022

In Chapter Six (‘Geophilia Entombed or the Boundaries of a Woman’s Mind’) I return once again to the archaeological record to discover the material remains of the horos. Horos was also inscribed upon the gravestone, a reminder for the living of this most basic of boundaries. Even here a limit remains, for it is only in our translation of the stone into a memorial that conjures up the ghost of the dead. With a study of ancient drama and the role burial rites play in the signification of death, I discover another aspect of the horos. Burial rites have long been associated exclusively with Sophocles’ Antigone and the conflict between two different regimes of justice. Horos is what remains as the trace of our division from nature, and it also marks the futility of this division since we must all and without exception inevitably find a home for ourselves in the earth, inevitably engraving us all in a common fate. In this guise, the horos describes the boundary between the human and the organic world but is also dependent, in the archaic period in particular, on a reciprocal relationship between the living and the dead: I call this the economics of death.
A Novel Disease Detection and Classification Method Using Improved Fusion Random Weight Support Vector Machine
Authors: Usha Rani M. , Saravana Selvam N.
Published: January 2022

Health informatics is one of the main branch of engineering which provides a solution to a variety of problems like delayed, missed or incorrect diagnoses with the help of computational techniques. With the help of technologies such as bio-computing, health informatics, the disaster
impacts on both human health and biological factors can be reduced to a large extend. Using these computational technologies, the country’s economy can also get boosted up and due to increased disease-causing pathogens, which directly impact the human health system. In this research
work, a different type of sugarcane disease is detected and classified because manual identification is difficult and time-consuming. So, the farmers couldn’t find a better solution, than on the whole, they go for stubble burning, which is an alarming issue both on human and environmental
wellness. The burning of bagasse causes bagassois, an interstitial lung disease that affects the tissues present in the lung through the air sacs. So, this sugarcane disease detection needs to be done early to avoid various health and environmental issues. The proposed work consists of the
detection of four types of sugarcane leaf disease directly from the field. The sequence of methods is capturing images with WSN nodes, pre-processing with image enhancement and noise removal (IENR), segmentation with Fuzzy membership function and clustering (FMFC), feature extraction using
Gray Level Co-occurrence Matrix Vector (GLCMV) and classification using Support Vector Machine (SVM). With the help of the effective proposed method, the highest parameters like precision, accuracy, sensitivity, and specificity for sugarcane leaf disease have been obtained. Based on the successful
implementation process, the accuracy stated for the four sugarcane diseases along with the execution time is given below as Smut disease (87.12, 1.01 sec), Rust disease (90.23, 1.02 sec), Grassy Shoot disease (95.34, 1.047 sec), Red Rot disease (95.51, 1.04 sec).
Optimization Techniques for Improving the Performance of Solar Photovoltaic System in Conjunction with Health Informatics and the Hospital Energy Management System
Authors: Elam Cheren S. , Ashok Kumar L.
Published: January 2022

Energy savings, clean energy, savings in utility and energy governance tools are buzzwords in the healthcare industry. Healthcare sectors become largest consumer of energy in the modern world. Based on data of American Society of Heating, Refrigerating, and Air-Conditioning Engineers
(ASHRAE), a moderate hospital consume 2.5 times higher energy than commercial buildings. As a result, increased worries about energy costs and environmental issues, as well as the anticipation of rising energy prices in the future and the need to enhance the dependability of healthcare facilities,
have led to a focus on in-house power generation systems and the importance of energy management in hospitals and their health care facilities. Solar power systems that are clean and ecologically friendly have grown in popularity as distributed power generation (DPG) systems in recent years.
In this work, a Grid-tied Solar PV system incorporated with Battery energy storage technology is considered in conjunction with health informatics and the hospital Energy Management System reduces energy consumption cost and improves the reliability of the power supply to run all clinical
equipment available in the hospital’s Intensive Care Unit (ICU) and other premises. In this context, the Energy management controller utilised in the hospital Energy Management System will effectively use the electricity supplied by the Solar PV system while minimising grid demand and
stabilising the voltage in the DC bus, which must be inverted into AC using an inverter to feed clinical loads. Furthermore the maximum power point tracking method is adopted, which enhances the quality of DC voltage generated by solar PV panels and feed to the DC bus. Sliding mode controller
(SMC) is adopted in the inverter side and the quality of the inverted voltage is optimized using artificial bee colony (ABC) method. The proposed solar PV system in conjunction with health informatics and the hospital Energy Management System is developed and simulated in the MATLAB Simulink.
The response of the suggested SMC and ABC techniques are compared and their outcomes are shown to confirm the performance of hospital energy management system.