bluuebunny/crossref_metadata_2025 huggingface dataset:
Calcitermin-Loaded Smart Gels Activity against Candida albicans: A Preliminary In Vitro Study
Authors: Bellotti Denise , D’Accolti Maria , Pula Walter , Huang Nicolas , Simeliere Fanny , Caselli Elisabetta , Esposito Elisabetta , Remelli Maurizio
Published: February 2023

Calcitermin is an antimicrobial peptide of 15 amino acids found in human nasal fluid characterized by antifungal and antibacterial properties. Candida albicans is the most common human fungal pathogen affecting many tissues, such as vaginal mucosa. In this study a formulation suitable for calcitermin administration on vaginal mucosa was developed for the treatment of fungal infections. To favor topical application, mucosal adhesion, and permanence, gels based on poloxamer 407 and xanthan gum were designed and compared with regard to their rheological behavior, erosion, and leakage. The selected gel was loaded with calcitermin, whose release kinetic was evaluated in vitro by Franz cells. An antifungal activity assay was conducted to assess the calcitermin anticandidal potential and the effect of its inclusion in the selected gel. The rheological study revealed the elastic and viscous moduli behavior as a function of poloxamer 407 and xanthan gum concentration. Xanthan gum presence decreased the transition temperature of the gel, while prolonging its erosion and leakage. Particularly, poloxamer 407, 18% and xanthan gum 0.4% were chosen. The calcitermin loading in the selected gel resulted in a transparent and homogeneous formulation and in a 4-fold decrease of the release rate with respect to the calcitermin solution, as evidenced by Franz cell study. The anticandidal activity tests demonstrated that calcitermin-loaded gel was more active against Candida albicans with respect to the peptide solution.
Study on the Low-Temperature Rheology of Polar Drilling Fluid and Its Regulation Method
Authors: Huang Ning , Lv Kaihe , Sun Jinsheng , Liu Jingping , Wang Jintang , Wang Zonglun
Published: February 2023

Drilling fluid is the blood of drilling engineering. In the polar drilling process, the ultra-low temperature environment puts high demands on the rheological performance of drilling fluids. In this paper, the effects of temperature, ice debris concentration and weighting agent on the rheological properties of drilling fluids were studied. It was found that the lower the temperature and the higher the ice debris concentration, the higher the drilling fluid viscosity, but when the ice debris concentration was below 2%, the drilling fluid rheology hardly changed. Secondly, the low temperature rheological properties of drilling fluid were adjusted by three different methods: base fluid ratio, organoclay, and polymers (dimer acid, polymethacrylate, ethylene propylene copolymer, and vinyl resin). The results showed that the base fluid rheological performance was optimal when the base fluid ratio was 7:3. Compared with polymers, organoclay has the most significant improvement on the low temperature rheological performance of drilling fluid. The main reason is that organoclay can transform the drilling fluid from Newtonian to non-Newtonian fluid, which exhibits excellent shear dilution of drilling fluid. The organoclay is also more uniformly dispersed in the oil, forming a denser weak gel mesh structure, so it is more effective in improving the cuttings carrying and suspension properties of drilling fluids. However, the drilling fluid containing polymer additives is still a Newtonian fluid, which cannot form a strong mesh structure at ultra-low temperatures, and thus cannot effectively improve the low-temperature rheological performance of drilling fluid. In addition, when the amount of organoclay is 2%, the improvement rate of the yield point reaches 250% at −55 °C, which can effectively improve the cuttings carrying and suspension performance of drilling fluid at ultra-low temperature.
Genealogical Systematics
Authors: Kluge Arnold G.
Published: February 2023

Genealogical research usually begins with the discovery of affinity among individual humans. Such kinship is induced by direct observation, as well as by hearsay (indirect observation) that can be independently confirmed. Those who want to continue investigating a case history after the observational mode of fact-finding is no longer sustainable have no other choice than to switch to the discovery of consanguineous relationships. This involves a paradigm shift, where investigation dramatically changes from observation to inference, from inductive to deductive reasoning. Individuation is important in characterizing the personhood of an individual, but those same facts are of little empirical value in establishing the unification of a family. In addition, genealogists rely on marriage as an observable source of evidence for unification. However, this extrapolation is not completely convincing because marriage does not take into account the uncertainty of paternity. Individual parents usually descend from different parts of family history, which suggests genealogists should evaluate cultural factors responsible for non-random mating in attempting to infer consanguinity. For example, there is the incest taboo, a cultural convention which addresses the abnormal genetic consequences of inbreeding. Other non-random mating factors of a more general nature may also be identified in the unification of genetically different individuals. Here, for example, causality is expected in cultural principles that are of a cohesive and integrative nature. Those kinds of evidence may determine an unmarried pair’s earliest engagement and may also be responsible for the origin and maintenance of the marriage relationship, even throughout post-reproductive life. Lastly, current genealogical research is severely infected with confirmation bias, and from which it must be protected if it is to achieve the status of a scientific discipline. Critical rationalism provides a solution to that kind of problem. It is with remediation in mind, as it applies to all of the aforementioned issues, that genealogical systematics is characterized.
Mineralogy, Geochemistry and Fluid Inclusion Study of the Stibnite Vein-Type Mineralization at Rizana, Northern Greece
Authors: Stergiou Christos L. , Sakellaris Grigorios-Aarne , Melfos Vasilios , Voudouris Panagiotis , Papadopoulou Lambrini , Kantiranis Nikolaos , Skoupras Evaggelos
Published: February 2023

The stibnite mineralization at Rizana (Kilkis ore district; Serbo-Macedonian metallogenic province; northern Greece) occurs along a NE–SW-trending brittle shear-zone, which transects a two-mica and an augen-gneiss of the Vertiskos Unit. Barren Triassic A-type granites and satellite pegmatites and aplites, as well as Oligocene-Miocene plutonic, subvolcanic and volcanic rocks that are variably hydrothermally altered and mineralized, outcrop in the broader region. The mineralization appears as veins, discordant lodes and disseminations. Veins and discordant lodes exhibit massive and brecciated textures. Historic underground mining (1930s–1950s) produced 9000 t of stibnite ore, grading 40% Sb on average. The main ore mineral assemblage includes stibnite + berthierite + sphalerite + pyrite + chalcopyrite + native antimony and traces of wolframite, galena, tetrahedrite, marcasite, pyrrhotite, arsenopyrite, realgar, native arsenic and native gold. Quartz, minor barite and ankerite are the gangue minerals. Sericitization and silicification developed along the shear-zone, forming hydrothermal halos of moderate intensity in the two-mica gneiss. Locally, valentinite, goethite and claudetite are present due to the supergene oxidation of the stibnite mineralization. Bulk ore geochemistry shows enrichments in specific elements including As, Au, Cd, Se, Tl and W. Fluid inclusion microthermometry showed that the mineralization was formed under a limited range of temperatures and salinities. The fluids had low to slightly moderate salinities (6.6–8.1 wt% equiv. NaCl) with low homogenization temperatures (217–254 °C, with a maximum at 220 °C).
Physical Activity, Body Image, and Its Relationship with Academic Performance in Adolescents
Authors: Guimarães José Pedro , Fuentes-García Juan Pedro , González-Silva Jara , Martínez-Patiño María José
Published: February 2023

Academic success in adolescence is a strong predictor of well-being and health in adulthood. A healthy lifestyle and moderate/high levels of physical activity can influence academic performance. Therefore, we aimed to assess the relationship between the physical activity levels and body image and academic performance in public school adolescents. The sample consisted of 531 secondary school students in Porto (296 girls and 235 boys) aged between 15 and 20 years. The study variables and instruments were satisfaction with body image (The Body Image Rating Scale), assessment of physical activity (International Physical Activity Questionnaire for Adolescents (IPAQ-A), assessment of academic performance (academic achievement), school motivation (Academic Scale Motivation). The statistical analysis performed was descriptive analysis, an analysis of covariance, and a logistic regression. Regarding the results obtained, although there was no association between physical activity level and academic performance, it was observed in 10th grade students that the school average was higher for those practicing group or individual sports compared to students practicing artistic expression. Regarding the level of satisfaction with body image, we found different results in both genders. Our results support the importance of an active lifestyle, with the presence of regular physical activity being an important factor in improving academic performance.
Perceptions on Their Own Social Participation: A Qualitative Exploration of Ethiopian Secondary Students with Visual Impairments
Authors: Yeshanew Yisma Tsige , Xu Tianxi , Yuan Wei
Published: February 2023

Social participation is a vital part of life and has multifaceted positive outcomes on personal health and wellbeing. Social participation or the lack thereof might have more profound psychological impacts on individuals in a collectivist culture than its counterpart. The current study explored personal and environmental barriers that have hindered the effective social participation of secondary students with visual impairments. Exploration addressed various activities in and outside school settings in Ethiopia and discussed findings in relation to the prevailing cultural orientation. In-depth semi-structured interviews were conducted to gather qualitative data on barriers to social participation of 17 secondary students with visual impairments in Addis Ababa, Ethiopia. The qualitative data were analysed thematically, yielding four major themes and identifying twenty sub-themes that limited the social participation of students with visual impairments, such as personal, attitudinal, sociocultural, and practical barriers. The study showed a range of barriers that participants experienced related to social participation, the criticality of cultural orientation in providing context to understand the impacts of social participation, and the need for future research in the area.
Challenges in Care for Non-COVID-19 Patients with Severe Chronic Illnesses during COVID-19 Pandemic: A Qualitative Study of Healthcare Providers Working around Acute Care Hospitals in South Korea
Authors: Kim Yejin , Shin Jeong Mi , Yoo Shin Hye , Keam Bhumsuk
Published: February 2023

Background: The COVID-19 epidemic has afflicted patients with severe chronic illnesses who need continuous care between home and hospitals. This qualitative study examines the experiences and challenges of healthcare providers around acute care hospitals who have cared for patients with severe chronic illness in non-COVID-19 situations during the pandemic. Methods: Eight healthcare providers, who work in various healthcare settings around acute care hospitals and frequently care for non-COVID-19 patients with severe chronic illnesses, were recruited using purposive sampling from September to October 2021 in South Korea. The interviews were subjected to thematic analysis. Results: Four overarching themes were identified: (1) deterioration in the quality of care at various settings; (2) new emerging systemic problems; (3) healthcare providers holding on but reaching their limit; and (4) a decline in the quality of life of patients at the end of their lives, and their caregivers. Conclusion: Healthcare providers of non-COVID-19 patients with severe chronic illnesses reported that the quality of care was declining due to the structural problems of the healthcare system and policies centered solely on the prevention and control of COVID-19. Systematic solutions are needed for appropriate and seamless care for non-infected patients with severe chronic illness in the pandemic.
The Impact of the COVID-19 Pandemic on Kidney Transplant Candidate Waitlist Status across Demographic and Geographic Groups: A National Analysis of UNOS STAR Data
Authors: Lombardi Conner V. , Lang Jacob J. , Li Meng-Hao , Siddique Abu Bakkar , Koizumi Naoru , Ekwenna Obi
Published: February 2023

The primary goal of this retrospective study is to understand how the COVID-19 pandemic differentially impacted transplant status across race, sex, age, primary insurance, and geographic regions by examining which candidates: (i) remained on the waitlist, (ii) received transplants, or (iii) were removed from the waitlist due to severe sickness or death on a national level. Methods: The trend analysis aggregated by monthly transplant data from 1 December 2019 to 31 May 2021 (18 months) at the transplant center level. Ten variables about every transplant candidate were extracted from UNOS standard transplant analysis and research (STAR) data and analyzed. Characteristics of demographical groups were analyzed bivariately using t-test or Mann–Whitney U test for continuous variables and using Chi-sq/Fishers exact tests for categorical variables. Results: The trend analysis with the study period of 18 months included 31,336 transplants across 327 transplant centers. Patients experienced a longer waiting time when their registration centers in a county where high numbers of COVID-19 deaths were observed (SHR < 0.9999, p < 0.01). White candidates had a more significant transplant rate reduction than minority candidates (−32.19% vs. −20.15%) while minority candidates were found to have a higher waitlist removal rate than White candidates (9.23% vs. 9.45%). Compared to minority patients, White candidates’ sub-distribution hazard ratio of the transplant waiting time was reduced by 55% during the pandemic period. Candidates in the Northwest United States had a more significant reduction in the transplant rate and a greater increase in the removal rate during the pandemic period. Conclusions: Based on this study, waitlist status and disposition varied significantly based on patient sociodemographic factors. During the pandemic period, minority patients, those with public insurance, older patients, and those in counties with high numbers of COVID-19 deaths experienced longer wait times. In contrast, older, White, male, Medicare, and high CPRA patients had a statistically significant higher risk of waitlist removal due to severe sickness or death. The results of this study should be considered carefully as we approach a reopening world post-COVID-19, and further studies should be conducted to elucidate the relationship between transplant candidate sociodemographic status and medical outcomes during this era.
Multidisciplinary Approach to the Diagnosis and Therapy of Mycosis Fungoides
Authors: Vitiello Paola , Sagnelli Caterina , Ronchi Andrea , Franco Renato , Caccavale Stefano , Mottola Maria , Pastore Francesco , Argenziano Giuseppe , Creta Massimiliano , Calogero Armando , Fiorelli Alfonso , Casale Beniamino , Sica Antonello
Published: February 2023

Mycosis fungoides is the most common primary cutaneous T-cell lymphoma, characterized by skin-homing CD4+ T cells derivation, indolent course, and low-grade of malignancy. Mycosis fungoides’s classic type typically onsets with cutaneous erythematous patches, plaque, and tumor. In WHO-EORTC classification, folliculotropic mycosis fungoides, pagetoid reticulosis, and granulomatous slack skin are recognized as distinct variants of mycosis fungoides, because of their clinical and histological features, behavior, and /or prognosis. Mycosis fungoides often shows diagnostic difficulties, due to its absence of specific features and lesional polymorphism. A patient’s treatment requires staging. In about 10% of cases, mycosis fungoides can progress to lymph nodes and internal organs. Prognosis is poor at advanced stage and management needs a multidisciplinary team approach. Advanced stage disease including tumors, erythroderma, and nodal, visceral, or blood involvement needs skin directed therapy associated with systemic drugs. Skin directed therapy includes steroids, nitrogen mustard, bexarotene gel, phototherapy UVB, and photochemiotherapy, i.e., total skin electron radiotherapy. Systemic therapies include retinoids, bexarotene, interferon, histone deacetylase inhibitors, photopheresis, targeted immunotherapy, and cytotoxic chemotherapy. Complexity of mycosis fungoides associated with long-term chronic evolution and multiple therapy based on disease stage need a multidisciplinary team approach to be treated.
Distress of Educators Teaching Nursing Students with Potential Learning Disabilities: A Qualitative Analysis
Authors: Murakami Mari , Kawasaki Hiromi , Cui Zhengai , Kokusho Hiroko , Kakehashi Masayuki
Published: February 2023

Clinical training at Japanese nursing universities has an increasing need for individualized learning support for students with potential learning disabilities. Despite a high interest in student support, educators’ difficulties are neglected. This study clarified the difficulties encountered by practical training instructors in delivering clinical training to nursing students with potential learning disabilities. In this descriptive, qualitative study, online focus group interviews were conducted. Participants were nine Japanese nursing university graduates with over five years of clinical education experience. A total of five categories were extracted: searching for measures tailored to students in a short period of time during training; resistance to individualized responses that significantly differ from traditional Japanese collectivist education; conflict over support being perceived as favoring a particular student; hesitation to identify students’ limits; and barriers in the process of supporting difficulties due to the nature of learning disabilities. Practical training instructors experience difficulties and hesitation when teaching students with potential learning disabilities. The practical training instructors need support and educational opportunities as well as students who need help. To overcome these difficulties, university educational staff, as well as students and families, must be educated on the existence and value of support tailored to the characteristics of an individual’s learning disability.
Successful Implementation of Menstrual Cycle Biomarkers in the Treatment of Infertility in Polycystic Ovary Syndrome—Case Report
Authors: Kicińska Aleksandra M. , Stachowska Aneta , Kajdy Anna , Wierzba Tomasz H. , Maksym Radosław B.
Published: February 2023

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Absent, impaired, or rare ovulation induces progesterone deficiency in the luteal phase, which is a critical problem in PCOS. A usual pattern of progesterone administration from a fixed and arbitrary pre-determined day of a menstrual cycle may preserve infertility but can easily be avoided. We present the case of a 29-year-old infertile woman who had been ineffectively treated for over two years. We introduced a line of therapy that was suited to her individual menstrual cycle by implementing biomarker recording. Supplementation based on a standardized observation of the basal body temperature (BBT) and cervical mucus stopped the vicious circle of absent ovulation and hyperandrogenism, restoring regular bleeding, ovulation cycles, and fertility. The implementation of a reliable fertility awareness method (FAM), accompanied by a standardized teaching methodology and periodic review of the observations recorded by the patient, validated through an ultrasound examination and plasma gonadotropins, estrogens, and progesterone concentrations, is key to achieving therapeutic success. The presented case is an example of a clinical vignette for many patients who have successfully managed to improve their fertility and pregnancy outcomes by applying the principles of a personalized treatment approach together with gestagens by recording their fertility biomarkers.
The Impact of COVID-19 Confinement on Substance Use and Mental Health in Portuguese Higher Education Students
Authors: Oliveira Ana Paula , Luis Henrique , Luís Luís Soares , Nobre Joana Rita , Pinho Lara Guedes , Albacar-Riobóo Núria , Sequeira Carlos
Published: February 2023

The mental health of higher education students is a constant concern, and the pandemic situation caused by COVID-19 has intensified this concern. The social measures imposed to control and minimize the disease have led, among other things, to the reconfiguration of higher education students’ academic life habits, which has naturally altered their emotional balance, mental health, and substance abuse. This cross-sectional, descriptive, and correlational study assesses the influence of higher education students’ personal characteristics on their (self-reported) use of addictive substances (alcohol, tobacco, drugs, and pharmaceutical drugs) before and during their first compulsory confinement in Portugal, as well as its relationship with mental health. An online questionnaire was applied between 15 April and 20 May 2020, to students from various study cycles of higher education institutions in one region of Portugal (northern area of Alentejo), which included the Mental Health Inventory in its reduced version (MHI-5) and questions (constructed by the authors) on personal characterization and on the use of addictive substances before and during confinement. The convenience sample included 329 mostly female health care students between the ages of 18 and 24. In our results, we found a statistically significant decrease in tobacco, alcohol, and drug use; however, there was an increase in tobacco use among older students and an increase in anxiolytic use among students with higher academic achievement and among students who exhibited more active social behavior in the period prior to confinement. Students who took anxiolytics during confinement had higher MHI-5 scores and students who used the most addictive substances during confinement had lower MHI-5 scores than the other students.
Physiological Features of Olympic-Distance Amateur Triathletes, as Well as Their Associations with Performance in Women and Men: A Cross–Sectional Study
Authors: Barbosa José Geraldo , de Lira Claudio Andre Barbosa , Vancini Rodrigo Luiz , dos Anjos Vinicius Ribeiro , Vivan Lavínia , Seffrin Aldo , Forte Pedro , Weiss Katja , Knechtle Beat , Andrade Marilia Santos
Published: February 2023

The purpose of this study was to verify the physiological and anthropometric determinants of triathlon performance in female and male athletes. This study included 40 triathletes (20 male and 20 female). Dual-energy X-ray absorptiometry (DEXA) was used to assess body composition, and an incremental cardiopulmonary test was used to assess physiological variables. A questionnaire about physical training habits was also completed by the athletes. Athletes competed in the Olympic-distance triathlon race. For the female group, the total race time can be predicted by V̇O2max (β = −131, t = −6.61, p < 0.001), lean mass (β = −61.4, t = −2.66, p = 0.018), and triathlon experience (β = −886.1, t = −3.01, p = 0.009) (r2 = 0.825, p < 0.05). For the male group, the total race time can be predicted by maximal aerobic speed (β = −294.1, t = −2.89, p = 0.010) and percentage of body fat (β = 53.6, t = 2.20, p = 0.042) (r2 = 0.578, p < 0.05). The variables that can predict the performance of men are not the same as those that can predict the triathlon performance of women. These data can help athletes and coaches develop performance-enhancing strategies.
Effects of Velocity-Based versus Percentage-Based Resistance Training on Explosive Neuromuscular Adaptations and Anaerobic Power in Sport-College Female Basketball Players
Authors: Zhang Mingyang , Li Duanying , He Jiaxin , Liang Xingyue , Li Dongyu , Song Wenfeng , Ding Shicong , Shu Jie , Sun Xiaoning , Sun Jian
Published: February 2023

The purpose of this study was to compare the impact of velocity-based resistance training (VBRT) and percentage-based resistance training (PBRT) on anaerobic ability, sprint performance, and jumping ability. Eighteen female basketball players from a Sport College were randomly divided into two groups: VBRT (n = 10) and PBRT (n = 8). The six-week intervention consisted of two sessions per week of free-weight back squats with linear periodization from 65% to 95%1RM. In PBRT, the weights lifted were fixed based on 1RM percentage, while in VBRT, the weights were adjusted based on individualized velocity profiles. The T-30m sprint time, relative power of countermovement jump (RP-CMJ), and Wingate test were evaluated. The Wingate test assessed peak power (PP), mean power (MP), fatigue index (FI), maximal velocity (Vmax), and total work (TW). Results showed that VBRT produced a very likely improvement in RP-CMJ, Vmax, PP, and FI (Hedges’ g = 0.55, 0.93, 0.68, 0.53, respectively, p < 0.01). On the other hand, PBRT produced a very likely improvement in MP (Hedges’ g = 0.38) and TW (Hedges’ g = 0.45). Although VBRT showed likely favorable effects in RP-CMJ, PP, and Vmax compared to PBRT (p < 0.05 for interaction effect), PBRT produced greater improvements in MP and TW (p < 0.05 for interaction effect). In conclusion, PBRT may be more effective in maintaining high-power velocity endurance, while VBRT has a greater impact on explosive power adaptations.
Adolescent Behaviours and Their Relationship to the Risk of Developing Eating Disorders
Authors: Tarifa Pérez Joaquín , Monserrat Hernández Montserrat , Arjona Garrido Ángeles , Salguero García Darío , Checa Olmos Juan Carlos
Published: February 2023

Eating disorders (ED) in adolescents represent a significant problem in today’s society, with multiple factors influencing them, such as predisposing factors, precipitating factors and perpetuating factors. Objective: This paper aimed to determine the relationships between some of the factors considered to be predisposing and precipitating in terms of the development of ED in adolescents and to relate them to the SCOFF index. Participants: The sample was made up of 264 subjects aged between 15 and 19 (48.8% females and 51.1% males). Methods: This study was conducted in two phases. In the first study phase, a descriptive analysis of the sample was performed, encompassing the frequencies of the independent variables and dependent variable (ED). In the second phase of study, we created several linear regression models. Results: A total of 11.7% of adolescents are at high risk for ED, and the variables that predict the variability of manifesting the danger of ED are the following: physical self-conception and family relationships. Conclusions: This work shows the need to approach eating disorders in a multidisciplinary way (biological and social), since this will enable the disease to be better conceptualized and prevention guidelines to be more effective.
Mycorrhization Enhances Vegetative Growth, Leaf Gas Exchange, and Root Development of Micropropagated Philodendron bipinnatifidum Schott ex Endl. Plantlets during Acclimatization
Authors: Dewir Yaser Hassan , Habib Muhammad M. , AlQarawi AbdulAziz A. , Alshahrani Thobayet S. , Alaizari Ahmed Ali , Malik Jahangir A. , Alwahibi Mona S. , Murthy Hosakatte Niranjana
Published: February 2023

Philodendron bipinnatifidum Schott ex Endl. is a popular ornamental plant that is normally propagated by tissue culture methods. However, the growth and acclimatization of micropropagated plants are tarrying processes. Therefore, in the present study we examined the effect of arbuscular mycorrhizal fungi (AMF) Gigaspora albida and G. marginata on the success in the establishment, growth, and development of P. bipinnatifidum plantlets during the acclimatization phase. AMF plants had significantly more leaves (10.67 per plant), leaf area (75.63 cm2), plant height (14.17 cm), shoot fresh weight (3.30 g) and shoot dry weight (0.31 g), according to an analysis of growth characteristics. In comparison, non-AMF plants had lower values for these metrics. In addition, AMF plants had significantly longer main roots (23 cm), total length roots per plantlet (485.73 cm), average root diameter (4.58 mm) per plantlet, number of root tips (236) per plant, total root surface area (697.76 cm2), total root volume (79.98 cm3), roots fresh weight (1.51 g), roots dry weight (0.16 g) than non-AMF plants. AMF-treated plants showed better performance in leaf gas exchange, chlorophyll, and carotenoid content. These results emphasize the need for mycorrhization of micropropagated plants to promote vegetative growth, especially during the acclimatization stage.
Correction: Bao, W.; Shen, Y. Dynamic Changes on Floral Aroma Composition of the Three Species from Tilia at Different Flowering Stages. Horticulturae 2022, 8, 719
Authors: Bao Wenqin , Shen Yongbao
Published: February 2023

In the original publication [...]
Attitudes and Feelings towards the Work of Teachers Who Had a School Nurse in Their Educational Center during the COVID-19 Pandemic
Authors: Santana-López Borja Nicolás , Bernat-Adell María Desamparados , Santana-Cabrera Luciano , Santana-Cabrera Esteban Gabriel , Ruiz-Rodríguez Gloria Raquel , Santana-Padilla Yeray Gabriel
Published: February 2023

The objective of this study was to analyze the influence of the availability of a health professional on the beliefs, attitudes, and work feelings of teaching staff when facing the COVID-19 pandemic. This is a two-phase study: In the first one, the Delphi technique was used to update an instrument used by the authors in a previous investigation in 2020. The second phase was a cross-sectional, descriptive, and comparative study, carried out through an electronic questionnaire distributed among the teaching staff of the Autonomous Community of the Canary Islands (Spain), during the first two months of the 2021/22 academic year, in the midst of the fifth wave of COVID-19. Data were analyzed using Pearson’s chi-squared test and the linear trend test. The reasons for advantages were analyzed and the dimensions of the questionnaire were compared between the groups studied (with or without a healthcare professional in the center). Out of 640 teachers in the study, 14.7% (n = 94) stated that they had a reference professional with health training in their educational center (a school nurse) for the management of possible cases of COVID-19. Significant differences were found in five of the nine dimensions studied between the groups of teachers analyzed. Teachers who had a health professional, specifically a nurse, during the pandemic indicated that they felt safer in their educational center, as they perceived that they had more personal protective equipment (OR = 2.03, [95% CI: 1.23–3.35]; p = 0.006). They were also more committed (OR = 1.89, [95% CI: 1.04–3.46]; p = 0.038) with their educational work and assumed more obligations (OR = 1.87, [95% CI: 1.01–3.44]; p = 0.045) and risks (OR = 2.82, [95% CI: 1.13–7.07]; p = 0.027). In addition, they presented fewer feelings of burnout (OR = 0.63, [95% CI: 0.41–0.98]; p = 0.041). These results indicate that having nurses in educational centers improves teachers’ ability to cope with a pandemic situation.
Spatio-Temporal Changes in Land Use and Habitat Quality of Hobq Desert along the Yellow River Section
Authors: Meng Ruibing , Cai Jiale , Xin Hui , Meng Zhongju , Dang Xiaohong , Han Yanlong
Published: February 2023

As a key area in the Yellow River basin for sand control and management, the land change process in the Hobq Desert plays a crucial role in keeping the river and desert ecosystems and promoting the construction of ecological civilization in human systems. Based on multi-temporal remote sensing from 1991 to 2019 in the Hobq Desert along the Yellow River section, this study selected spatial statistical methods (land-use monitoring and landscape metrics) to examine land-use change dynamics. Then, we evaluated habitat quality using the InVEST model and quantitatively analyzed the factors causing spatial changes in habitat quality using geographic detectors. Finally, this paper predicted the pattern of land use and habitat quality in 2030 using the PLUS model. The results reveal that (1) from 1991 to 2019, the total area of forest grassland increased by 3572.5 km2, providing the most vegetation cover, and the sandy land and water area decreased continuously, while the cultivated land and construction land increased. There were 38.01% conversions of land types, with the land-use dynamic decreasing the greatest in sandy land (−12.66%) and increasing the greatest in construction land (9.26%); the comprehensive land-use dynamics were the highest in 2010–2019 (1.68%), which was the most active stage during our study period. (2) Both of the landscape indices NP and PD showed “N” type fluctuations during 1991–2019, and CONTAG and LSI rose from 69.19% to 70.29% and 36.01% to 38.89%, respectively, indicating that the land-use degree of landscape fragmentation increased, landscape connectivity turned better, and landscape dominance was enhanced, balanced, and developed evenly in overall landscape type. (3) From the overall region analysis, the average habitat quality in 1991, 2000, 2010, and 2019 was 0.3565, 0.5108, 0.5879, and 0.6482, respectively, with the overall habitat value showing a gradually increasing trend. Spatially, the habitat quality along the Yellow River section of the Hobq Desert has a certain regularity, and the overall pattern there is high in the south and low in the north, high in the east and west, and low in the middle. (4) The change in land use between 2019 and 2030 is similar to the previous period, but the change rate is generally lower. The habitat quality improved significantly, with the growth of high and medium habitat quality.
Motivators and Influencers of Adolescent Girls’ Decision Making Regarding Contraceptive Use in Four Districts of Zambia
Authors: Chola Mumbi , Hlongwana Khumbulani W. , Ginindza Themba G.
Published: February 2023

Low contraceptive use in sub-Saharan Africa, and Zambia specifically, negates the potential benefits of contraception in preventing unwanted and early pregnancies. This study aimed to explore and understand the motivators and influencers of adolescent girls’ contraceptive decision making. Using thematic analysis, we analysed qualitative data from seven focus group discussions and three key informant interviews with adolescent girls aged 15 to 19 years in four Zambian districts. The data were managed and organised using NVivo version 12 pro (QSR International). Fear of pregnancy, fear of diseases, fear of having more children, and spacing of children (especially among married adolescents) were key motivators for adolescents’ contraceptive use. Friends and peers motivated them to use contraceptives while fear of side effects and fear of infertility drove non-use. Peer pressure and fear of mocking by their friends were important deterrents to contraceptive use. Parents, peers and friends, family members, partners, churches, and religious groups influenced adolescent girls’ contraceptive decisions. Mixed messages from these influencers, with some in favour and others against contraceptives, make adolescents’ decisions to use contraceptives complex. Therefore, interventions targeting increased contraceptive use should be all-inclusive, incorporating multiple influencers, including at institutional and policy levels, to empower adolescents and give them autonomy to make contraceptive decisions.
Religiosity, Theism, Perceived Social Support, Resilience, and Well-Being of University Undergraduate Students in Singapore during the COVID-19 Pandemic
Authors: Gan Samuel Ken-En , Wong Sibyl Weang-Yi , Jiao Peng-De
Published: February 2023

The COVID-19 pandemic infection control measures severely impacted mental well-being, allowing insight into possible protective parameters. With religion playing a role during challenging times, this study investigated theism and religiosity on the mental well-being of university students during the COVID19 pandemic and how social support and resilience can mediate this effect. One hundred eighty-five university students between 17 and 42 years old responded to online surveys on their theism, religious affiliations, religiosity, well-being, perceived support, and resilience. Pearson’s correlations and single and sequential mediation analyses showed that theism did not significantly predict well-being (r = 0.049), but religiosity mediated the relationship (r = 0.432, effect size = 0.187). Sequential mediation analysis showed that resilience did not mediate the relationship between religiosity and well-being, but perceived social support significantly positively mediated religiosity and well-being with an effect size of 0.079. The findings reveal that factors, such as religiosity and social support could thus aid in the mental well-being of future challenging times such as the pandemic.
Perception of Remote Learning by Fixed Prosthodontic Students at a Romanian Faculty of Dentistry
Authors: Tanculescu Oana , Apostu Alina-Mihaela , Doloca Adrian , Solomon Sorina Mihaela , Diaconu-Popa Diana , Ciongradi Carmen Iulia , Vieriu Raluca-Maria , Aungurencei Ovidiu , Fatu Ana-Maria , Ioanid Nicoleta , Scurtu Mihaela , Saveanu Catalina Iulia
Published: February 2023

The COVID-19 pandemic has forced the transfer of traditional on-site educational activities to the online environment. This study aimed to evaluate the perception and acceptance of remote learning among fixed prosthodontic students attending the Faculty of Dental Medicine of “Grigore T. Popa” University of Medicine and Pharmacy in Iasi, Romania, and to analyze the feedback regarding their experience with the new online methods, the perceived quality thereof and suggestions for improvement. An observational cross-sectional, online study based on 22 questions was conducted with 259 students. The general opinion of online education was good or very good (40.15%); regarding its efficiency, 28.57% found it efficient while 34.36% found it inefficient or very inefficient; regarding the pleasure of learning online, 45.95% of students enjoyed online learning, while 36.64% did not enjoy it. The problem that was most cited by respondents was that of keeping all students motivated and involved (65.6%). Sixty-two percent of the respondents believe that online dental education should not exist, or just to a small extent, a result justified by the practical nature of the profession. The general opinion was that health risks should be managed and mitigated by using a hybrid system that would allow students to do on-site clinical training with direct contact with patients.
Toxicity of Tetracycline and Metronidazole in Chlorella pyrenoidosa
Authors: Li Junrong , Wang Yingjun , Fan Ziqi , Tang Panyang , Wu Mengting , Xiao Hong , Zeng Zhenxing
Published: February 2023

Antibiotics have become a new kind of organic pollutant as they are widely used in the water environment of China. Tetracycline (TC) is a class of broad-spectrum antibiotics produced or semi-synthesized by actinomycetes. Metronidazole (MTZ) is the first generation of typical nitroimidazoles. The content of nitroimidazoles is relatively high in medical wastewater, and their ecotoxicity is worthy of attention because they are difficult to completely eliminate. In this paper, the effects of TC and MTZ on the growth, cell morphology, extracellular polymer and oxidative stress of Chlorella pyrenoidosa (C. pyrenoidosa) were studied, and the toxic interactions between TC and MTZ mixture components were analyzed. The results showed that the 96h-EC50 of TC and MTZ was 8.72 mg/L and 45.125 mg/L, respectively. The toxicity of TC to C. pyrenoidosa was higher than that of MTZ, and the combined toxicity effect of TC and MTZ was synergistic after the combined action of a 1:1 toxicity ratio. In addition, the algal cells of C. pyrenoidosa died to varying degrees, the membrane permeability of algal cells was increased, the membrane was damaged, the surface of algal cells exposed to higher concentration of pollutants was wrinkled, and their morphology was changed. The extracellular polymer of C. pyrenoidosa was affected by a change in concentration. The effect of pollutants on the reactive oxygen species (ROS) level and malondialdehyde (MDA) content of C. pyrenoidosa also had an obvious dose–effect relationship. This study contributes to the assessment of the possible ecological risks to green algae due to the presence of TC and MTZ in aquatic environments.
Exercise-Induced Elevated BDNF Concentration Seems to Prevent Cognitive Impairment after Acute Exposure to Moderate Normobaric Hypoxia among Young Men
Authors: Chroboczek Maciej , Kujach Sylwester , Łuszczyk Marcin , Soya Hideaki , Laskowski Radosław
Published: February 2023

Memory impairment, reduced learning ability, decreased concentration, and psychomotor performance can be all signs of deleterious impact of hypoxia on cognitive functioning. In turn, physical exercise can improve performance and enhance cognitive functions. The purpose of this study was to investigate whether the potential positive effects of exercise performed under normobaric hypoxia can counteract the negative effects of hypoxia on cognitive function, and whether these changes correlate with brain-derived neurotrophic factor (BDNF) concentrations. Seventeen healthy subjects participated in a crossover study where they performed two sessions of single breathing bouts combined with moderate intensity exercise under two conditions: normoxia (NOR EX) and normobaric hypoxia (NH EX). To assess cognitive function, Stroop test was applied. There were no significant differences in any part of the Stroop interference test regardless of the conditions (NOR, NH), despite a statistical decrease in SpO2 (p < 0.0001) under normobaric hypoxic conditions. In addition, a statistical increase (p < 0.0001) in BDNF concentration was observed after both conditions. Acute exercise under normobaric hypoxia did not impair cognitive function despite a significant decrease in SpO2. Exercise in such conditions may offset the negative effects of hypoxia alone on cognitive function. This may be related to the significant increase in BDNF concentration and, as a consequence, positively affect the executive functions.
Prosociality and Personality: Perceived Efficacy of Behaviors Mediates Relationships between Personality and Self-Reported Climate Change Mitigation Behavior
Authors: Nezlek John B. , Cypryańska Marzena
Published: February 2023

The included studies examined the relationship between climate change mitigation behavior (CCB) and personality. In Study 1, 1089 US collegians completed a measure of the Big Five and indicated how often they engaged in five CCBs. Engaging in each CCB was regressed on the Big Five. These analyses found openness was positively related to all five CCBs, neuroticism was positively related to four of five CCBs, and extraversion was positively related to three CCBs. In Study 2, 1688 US collegians completed the same measures as in Study 1 with two additional CCBs. They also indicated how efficacious they thought each CCB was. Each CCB was regressed on the Big Five. These results largely replicated those of Study 1 and also found that conscientiousness was positively related to five of seven CCBs. Mediational analyses found that all relationships between personality factors and CCB were mediated by the perceived efficacy of the CCB. The present results suggest that efforts to increase climate change mitigation behavior need to take into account the perceived efficacy of such behaviors.
How Have Physical Activity and Sedentary Behavior, Changed during the COVID-19 Pandemic? A Swedish Repeated Cross-Sectional Design Study
Authors: Lindberg Daniel , Elvén Maria , Nilsson Kent , Von Heideken Wågert Petra , Stier Jonas , Dahlen Micael , Kerstis Birgitta
Published: February 2023

Physical activity (PA) and sedentary behavior (SB) affect people’s physical and mental health. The aim was to examine changes in PA and SB in a Swedish population: at three time points: 2019, 2020, and 2022, i.e., before and during the COVID-19 pandemic. Pre-pandemic PA and SB, i.e., 2019, were assessed retrospectively in 2020. Associations between PA and SB with sex, age, occupation, COVID-19 history, weight change, health, and life satisfaction were also examined. The design was repeated cross-sectionally. The main findings demonstrate the PA levels decreased between 2019 and 2020, and between 2019 and 2022, but not between 2020 and 2022. The SB increase was most evident between 2019 and 2020. Between 2020 and 2022, results showed a decrease in SB, but SB did not reach pre-pandemic levels. Both sexes decreased their PA over time. Although men reported more PA sex, they did not have any association with PA changes. Two age groups, 19–29 years and 65–79 years, decreased their PA over time. Both PA and SB were associated with COVID-19, occupation, age, life satisfaction, health, and weight change. This study underlines the importance of monitoring changes in PA and SB as they have relevance for health and well-being. There is a risk that the levels of PA and SB do not return to pre-pandemic levels in the population.
Distance to Natural Environments, Physical Activity, Sleep, and Body Composition in Women: An Exploratory Analysis
Authors: Teixeira Andreia , Gabriel Ronaldo , Martinho José , Oliveira Irene , Santos Mário , Pinto Graça , Moreira Helena
Published: February 2023

A growing body of evidence indicates that living close to nature is associated with better health and well-being. However, the literature still lacks studies analyzing the benefits of this proximity for sleep and obesity, particularly in women. The purpose of this study was to explore how distance to natural spaces is reflected in women’s physical activity, sleep, and adiposity levels. The sample consisted of 111 adult women (37.78 ± 14.70). Accessibility to green and blue spaces was assessed using a geographic-information-system-based method. Physical activity and sleep parameters were measured using ActiGraph accelerometers (wGT3X-BT), and body composition was assessed using octopolar bioimpedance (InBody 720). Nonlinear canonical correlation analysis was used to analyze the data. Our findings reveal that women living in green spaces close to their homes had lower levels of obesity and intra-abdominal adiposity. We also demonstrated that a shorter distance to green spaces seemed to correlate with better sleep onset latency. However, no relationship was found between physical activity and sleep duration. In relation to blue spaces, the distance to these environments was not related to any health indicator analyzed in this study.