bluuebunny/crossref_metadata_2025 huggingface dataset:
SMEs’ SUPPLY CHAIN PERFORMANCE: THE ROLE OF COLLABORATION, CAPABILITIES AND INNOVATION
Authors: Arsawan I Wayan Edi , Koval Viktor , Suhartanto Dwi , Babachenko Larysa , Kapranova Larysa , Suryantini Ni Putu Santi
Published: June 2022

This study aims to assess supply chain performance in the context of SMEs including supply chain collabora-tion and capabilities, as well as innovation performance as the drivers and analyse the moderating role of knowledge sharing on the relationship between supply chain collaboration and innovation, as well as the collaboration and sup-ply chain performances. The data were obtained from 179 SMEs involving 537 respondents in nine districts of Bali, Indonesia. Furthermore, a partial least square modelling was used to evaluate the proposed supply chain performance model. The present study generated three important findings; 1) supply chain collaboration has a significant effect on supply chain capability, innovation performance and supply chain performance, 2) innovation performance has no significant effect on supply chain performance, and 3) knowledge sharing acts as a moderating variable of the relation-ship between supply chain collaboration and innovation performance. By testing the research model conceptually and verifying it empirically, we contribute to the study of the relationship between collaboration and the capability of SMEs to generate innovation and supply chain performance.
E-LEADERSHIP COMPETENCES – THE IMPACT OF MEDIA USE AND ORGANIZATIONAL INFLUENCE
Authors: Kempner Frauke
Published: June 2022

E-Leadership as a new leadership paradigm is located in the field of tension between social (cohesion) and organizational (locomotion) basic orientations. The managers of the future need special skills in this field, which are significantly characterized by the use and influence of digital media. Even if there is agreement in the literature that the previous competencies of a classic leadership are not sufficient, the previous research does not yet provide a consistent competency profile. This gap is to be closed by means of a first cross-sectional study by which reference points for a first competence profile are to be given. Thereby, the special influence of Media Use and Organizational Influence is proved.
CORPORATE DECISIONS TO CONTRIBUTE TO NON-STATE SOCIAL PROTECTION IN GHANA WITHIN THE COVID-19 CONTEXT
Authors: Baah Richmond
Published: June 2022

In 2020, the private sector in Ghana established the Ghana COVID-19 Private Sector Fund to pool resources to, among others, construct the country’s first infectious disease centre in response to the COVID-19 pandemic. This research aims to: (a) identify the factors that enabled the decisions of private corporate managers to contribute to non-state social protection through the Fund; and (b) explore how wise their decisions to contribute to non-state social protection through the Fund are. Methodology: Content analysis and semi-structured interviews were performed. Conclusion: Based on the factors identified in this research, the decisions of the private sector to establish and contribute to the Fund were informed by wisdom. The research validates the wise management decision-making model and the assertion that managers need to take decision based on wisdom when they are confronted with wicked problems.
Travel-associated outbreak of COVID-19 in a departmental store, Wenzhou, China
Authors: Zhou Yiwei , Xiang Fanglv , Ni Chaorong , Zhang Xiaoming , Xie Haibin , Zhu Haishen , Zhou Zumu
Published: June 2022

Introduction: A local outbreak of coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic and the number of cases and deaths has increased exponentially. In this study, we report a COVID-19 outbreak that occurred in a departmental store, between January and February 2020, in Wenzhou, China and investigated the reasons for the outbreak.

Methodology: An outbreak investigation was initiated after the index case was diagnosed as COVID-19. Cases (confirmed and suspected) and close contacts were defined. Their pharyngeal swabs were collected and examined with real-time polymerase chain reaction (RT-PCR) for nucleic acid. All investigations of the confirmed and suspected cases were carried out by epidemiologists and the source of infection was tracked by using big data.

Results: Thirty-nine COVID-19 cases and one asymptomatic individual were found in this outbreak, as determined by clinical manifestations, epidemiological investigation, and RT-PCR. Majority of COVID-19 cases occurred in a departmental store, three of whom traveled to participate in a meeting held in H city. After disease outbreak in the departmental store, intra-family transmission of COVID-19 occurred in five families. Two clusters of the COVID-19 outbreak were identified. One cluster was attributed to the family party, while another was attributed to a hotel party, which was responsible for transmission across three generations, infecting five family members.

Conclusions: This was travel associated COVID-19 outbreak in a departmental store in Wenzhou, China. High infectivity of COVID-19 was observed. A departmental store, especially without recirculation of the air, was a high-risk site for the transmission of COVID-19. The use of big data and related information was very useful in epidemiological investigation of cases and contacts.
Compliance of abstracts of randomized control trials with CONSORT guidelines: A case study of Balkan journals
Authors: Sut Necdet , Koçak Zafer , Korkmaz Selcuk , Uzun Cem
Published: June 2022

Background: Published reports of randomized controlled trials (RCTs) are not compliant with the CONSORT checklist as much as they should.

Objective: To assess the quality, in terms of the level to which they are compliant with the CONSORT checklist, of abstracts of RCTs published in general medical journals in the Balkan region.

Methods: Two observers assessed the abstracts of RCTs published in five general medical journals of the Balkan region between 2012 and 2018 to determine the level to which the abstracts were compliant with the 16-item CONSORT abstracts checklist.

Results: Of the 183 studies that were identified for evaluation, 124 (67.8%) were excluded from the evaluation. The average compliance level was 44.5% (95%   CI: 41.9%–47.1%), the lowest being that for randomization (1.7%), funding (1.7%),

numbers analysed (11.0%), blinding (13.6%), and trial registration (18.6%). However, the compliance level was very high for conclusions (99.2%), objectives (96.6%), interventions (95.8%), and primary outcomes (83.9%). The length of the abstract (word count) and the level of compliance were positively correlated (rs = 0.43; p = 0.001). Abstracts of trials published in journals that endorse CONSORT in their publication policies were more compliant than those published in other journals (47.5 ± 10.4 versus 40.8 ± 8.0, p = 0.024).

Conclusion: The overall level of compliance with the CONSORT checklist was below 50%. To improve the quality of abstracts of RCTs, authors should be encouraged to use the CONSORT checklist, and editors should check compliance with the CONSORT guidelines as part the publishing workflow.
Morphological and molecular analyses reveal two new species of Gibellula (Cordycipitaceae, Hypocreales) from China
Authors: Chen MingJun , Wang Ting , Lin Yan , Huang Bo
Published: June 2022

Gibellula penicillioidessp. nov. and G. longisporasp. nov., two new species parasitising spiders collected in China, are illustrated and described, based on morphological features and multiloci phylogenetic analysis. The G. penicillioidessp. nov. group is sister to the G. scorpioides group, but form long penicilloid conidiophore producing enlarged fusiform conidia ((7–) 7.5–9 (–10) × 2.5–3.5 μm). G. longisporasp. nov. is sister to G. pigmentosinum, but has slender long conidia (5–7 × 1–2 μm); teleomorph and Granulomanus-synanamorphic conidiogenous cells are absent in these two species. Type specimens of G. penicillioidessp. nov. and G. longisporasp. nov. were deposited in the Anhui Agricultural University (RCEF). In addition, a key to all known species of Gibellula is illustrated.
D’une compétition l’autre : le Zaouli gouro, le patrimoine immatériel et le politique
Authors: Haxaire Claudie
Published: June 2022

Performance de masques gouro, Zaouli a été inscrit au patrimoine immatériel de l’Unesco en 2017, accomplissement d’un parcours international au départ duquel nous retrouvons le premier président de la Côte d’Ivoire, Félix Houphouët-Boigny. Cet article étudie le rôle joué par les premiers députés qui favorisèrent la carrière internationale des troupes de leur territoire, puis par les hommes politiques et leurs administrations dans la « festivalisation » et la patrimonialisation de cette tradition. Différentes versions de cette performance ont émergé, polysémiques, simplifiées ou « canonique » – celle que la patrimonialisation a exhumée. Les chorégraphes contemporains s’en saisissent. Les performances de Zaouli, figure de l’alliance et de la paix, survenaient après que son ancêtre sacré laid Zàùlì (tons bas) ait assaini l’espace de tous dangers nés de conflits non résolus. Il s’agissait de deux temps différents, ce que font mine d’oublier les jeunes de l’un des villages qui ont rabattu les deux figures sur une version hybride, qu’entérine le processus de patrimonialisation. Extraire Zaouli de son contexte occulte les conflits dont il marquait la résolution. Quand la nation de paix dont Zaouli est l’un des emblèmes paraît une utopie que l’histoire ne cesse de mettre à mal, cette distinction est essentielle.
Le glas de la globalisation ?
Authors: Brun Matthieu
Published: June 2022

La souveraineté alimentaire mobilise de plus en plus les esprits à l’aune des crises alimentaires répétées. Jusqu’à remettre en cause la mondialisation, longtemps perçue comme seul horizon ?
Flambées à réguler
Authors: Galtier Franck , De Schutter Olivier , Hervieu-Léger Benoît
Published: June 2022

La crise actuelle rappelle de près les précédentes, avec une hausse des prix de l’énergie répercutée sur les denrées alimentaires. La guerre en Ukraine amplifie l’équation, mais des solutions de régulation existent. Entretien.
Vers une Sécu alimentaire ?
Authors: Petersell Laura , Certenais Kévin , Hervieu-Léger Benoît
Published: June 2022

Appliquer le principe d’une sécurité sociale au domaine de l’alimentation, tel est l’horizon pour lequel plaident Laura Petersell et Kévin Certenais dans un récent ouvrage. Une révolution qui n’irait pas sans remise à plat de la filière.
Bombe alimentaire mondiale
Authors: Marie Anaïs
Published: June 2022

Plus de deux milliards d’individus dépendent de la Russie et de l’Ukraine en matière d’alimentation. Les autres pays exportateurs ne pourront compenser seuls le déséquilibre des marchés suscité par la guerre.
La violence au microscope
Authors: Guillou Benoît
Published: June 2022

Dans des contextes de crimes de masse en Syrie et en RDC ou du génocide au Rwanda, cet ouvrage explore les démarches adoptées pour rendre compte des violences extrêmes.
L’évaluation des apprentissages comme passages entre mondes de problèmes, de pratiques et de savoirs
Authors: Ravachol Denise Orange , Boyer Catherine
Published: June 2022

Notre étude inscrit la question de l’évaluation en situant le sujet apprenant à la croisée de plusieurs « mondes » (la famille, l’École, la classe, etc.) , et tente de rendre compte des conditions d’un passage assumé de ce sujet d’un « monde » à un autre. C’est une façon d’éviter une approche généraliste et techniciste de l’évaluation des apprentissages et de dépasser l’idée que si elle s’inscrit dans le « concret » de l’élève, elle en facilite sa réussite. En prenant le cas, à l’école primaire, d’une séquence de classe ordinaire sur l’alimentation, nous montrons que l’élève, l’enseignant et la classe fonctionnent et peuvent se rabattre dans des mondes qui ne sont pas a priori ceux que l’institution École dit viser.
S’assurer de la validité didactique des évaluations en milieux scolaires
Authors: Grapin Nadine , Vantourout Marc , Grugeon-Allys Brigitte
Published: June 2022

La validité d’une évaluation est appréhendée dans cet article selon deux approches didactiques complémentaires : l’une anthropologique et épistémo-didactique, l’autre psycho-didactique. Nous montrons et illustrons en quoi cette conception renouvelée de la validité qui articule qualitatif et quantitatif permet d’outiller les concepteurs et utilisateurs d’évaluations, qu’elles soient internes ou externes : un premier exemple est donné en mathématiques avec l’étude d’une évaluation à grande échelle et un second exemple en lecture-compréhension de textes, en lien avec un dispositif de formation d’enseignants.
Stock et flux
Authors: Gilliotte Quentin
Published: June 2022

Comment les individus classent et organisent les biens culturels numériques ? Pour les biens physiques, classer ses DVD, ses jeux vidéo, ou ses CD par taille, support, genre, auteur, ordre de consommation correspond à des formes d’engagement qui viennent soutenir la consommation des biens culturels, lui donner du sens. Quand il s’agit des biens numériques et qu’il n’y a plus de classification à établir par soi-même, de quelles façons se manifestent les différents niveaux d’engagement dans la pratique ? Nous nous appuyons sur plus de 60 entretiens semi-directifs et sur les données issues d’un questionnaire administré auprès de plus de 2000 répondants par méthode des quotas. L’article montre comment les individus mettent en place des architectures attentionnelles pour ordonner les biens culturels en stock et en flux. Ces pratiques se transforment, et se déplacent de plus en plus vers des formes idiosyncrasiques de classement où l’individu est le principal horizon des pratiques de classification. Il s’agit moins d’ordonner les biens numériques selon des critères institutionnels (le genre, la date, l’ordre alphabétique) que selon des logiques de gestion personnelle de sa consommation.
Repenser l’urbain depuis l’Afrique
Authors: Panata Sara
Published: June 2022

Cet article propose une analyse croisée des mobilisations féminines et masculines lors de la crise politique de la Région occidentale du Nigéria (1962/1965) telle qu’elle est vécue à Ibadan. Dans un espace urbain militarisé, l’activité des militants se déroule dans les bâtiments publics ou dans la clandestinité alors que les militantes adoptent des formes variées d’action politique. La radicalisation de la situation politique va de pair avec une radicalisation de moyens de contestation employés par les militantes : elles transforment leurs espaces ordinaires en espaces politiques à travers de chants de dérision ; elles marchent en semi-nudité et avec des signes des combats dans des lieux du pouvoir dont elles sont normalement exclues ; elles participent à des tueries dans un espace extra-urbain qui échappe au contrôle policier. Naviguant entre des formes d’action multiples, cet article a pour objectif de rendre compte de nouvelles divisons genrées du travail militant et de restructurations genrées de l’espace urbain par et pour le conflit politique.
Les compétences interculturelles et la coopération internationale : le cas des échanges germano-maghrébins
Authors: Ben Abid-Zarrouk Sandoss , Nal Emmanuel
Published: June 2022

Depuis 2019, le projet The Moroccan Entrepreneurial University Initiative , mené pour développer l’employabilité des étudiants diplômés par l’acquisition de compétences professionnelles, réunit deux universités allemandes, deux universités marocaines, deux tunisiennes et l’Université de Haute-Alsace. Mais cette expérience fit constater que la seule maîtrise de l’anglais ne suffisait pas à permettre des échanges internationaux constructifs et efficaces ; un an après le début du projet, des incompréhensions et certaines tensions rendirent indispensable une formation à la compétence interculturelle pour permettre aux acteurs d’acquérir ces savoirs et savoir-être indispensables afin de poursuivre le projet. Cet article va dans un premier temps resituer les fondements théoriques de la compétence interculturelle, pour mieux permettre d’analyser les situations où elle a fait défaut. Il va ensuite présenter une analyse qu’il définit comme une étude de cas pour permettre d’ancrer certains effets d’une formation aux compétences interculturelles dans un contexte de coopération internationale.
A Randomized Controlled Trial of the Veterans Coping Long Term With Active Suicide (CLASP) Program
Authors: Primack Jennifer M. , Bozzay Melanie L. , Gaudiano Brandon A. , Weinstock Lauren M. , Armey Michael F. , Brick Leslie A. , Holman Caroline S. , Miller Ivan W.
Published: June 2022

Veteran suicide rates remain unacceptably high despite recent initiatives and the surge in new prevention programs. Many suicide prevention interventions are treatment intensive and require significant training and expertise to deliver, and few have been developed and tested specifically for veterans. The Coping Long Term with Active Suicide Program (CLASP) is an adjunctive telephone-based suicide prevention program designed to reduce suicide behaviors after psychiatric hospitalization. CLASP was modified and tested with a veteran sample. One hundred three veterans hospitalized for suicide risk were randomized to CLASP versus Veterans Affairs' treatment as usual and observed for 12 months after hospital discharge. All veterans, regardless of treatment condition, showed a reduction in both suicide behaviors and rehospitalization during a 12-month period. Implications for Veterans Affairs suicide prevention are discussed.

[
Psychiatr Ann
. 2022;52(5):199–207.]
An Online Resilience Intervention for Military Personnel
Authors: Millstein Rachel A. , McCarthy Megan D. , Chudnofsky Rana , Fredriksson Stacie , Francona Jacqueline , Winklosky Tricia , Sampson Brianne , Mulzoff Ariel , Hirschberg Ronald E. , Park Elyse R. , Fricchione Gregory , Mehta Darshan H. , Denninger John , Sylvia Louisa G.
Published: June 2022

Mind-body programs can improve mental health and well-being in military populations. This pilot study of a virtual synchronous resilience intervention was conducted from 2018 to 2020 among 26 military personnel. Participants completed self-report psychosocial questionnaires before and after the 6-week program, including measures of posttraumatic stress disorder, depression, stress, resilience, and mindfulness. The intervention included eliciting the relaxation response, adaptive coping strategies, and healthy behaviors. Pre-post changes were calculated using paired
t
tests and effect sizes (
d
). Significant improvements were found for depression (Patient Health Questionnaire-8), stress reactivity (Measure of Current Status-Abbreviated Scale), and mindfulness (Cognitive Affective Mindfulness Scale-Revised). A 6-week resilience intervention can help military personnel improve mental health, coping, and stress management.

[
Psychiatr Ann
. 2022;52(5):186–190.]
The geominimal integral curvature
Authors: Mou Shuang
Published: June 2022

In this paper, the geominimal integral curvature on the convex body is introduced. The existence and uniqueness of the geominimal integral curvature are proved. Some other properties for the geominimal integral curvature, such as continuity, are investigated.
Les inventaires et le rôle de la statuaire grecque dans la Rome antique
Authors: van de Velde Suzan
Published: June 2022

À partir de la fin du iiie siècle avant notre ère, nombre de statues grecques furent transportées à Rome. Ces sculptures étaient exposées dans des contextes publics de la ville et furent au fil du temps déplacées et relocalisées. Cet article explore les systèmes administratifs romains qui ont inscrit ces « nouveaux » objets d’art à leur arrivée à Rome et qui ont enregistré leurs transferts successifs dans différents contextes. Le Cheval de bronze, statue grecque du ve siècle avant notre ère, porte des inscriptions qui sont très probablement des « numéros d’inventaires » faisant référence aux registres romains. En analysant cette œuvre du point de vue matériel, l’autrice défend que les inscriptions sur ces statues n’apportent pas seulement un éclairage sur les processus de leur transport dans la Rome antique, mais démontrent aussi que les inventaires fonctionnaient comme des moyens de contrôle sur ces objets mus dans la ville.
Role of Training Transfer in the Aftermath of the COVID-19 Pandemic
Authors: Dixit Ramnath , Sinha Vinita
Published: June 2022

This chapter aims to highlight the significance of training transfer in organizations in the aftermath of the COVID-19 pandemic. Transfer of training has always been sidelined in companies for various reasons, and this problem aggravates during situations such as the pandemic or economic upheavals. It is imperative that workplace transfer is given its due credit in the learning and development framework to ensure successful implementation of trained skills and knowledge thereby justifying the training investments made. The chapter highlights the bottlenecks that need to be addressed towards training transfer in the context of a post-pandemic scenario and also suggests practical recommendations to overcome these challenges.
Strategic Organizational Resilience as a Response to the Crisis
Authors: Vargas-Hernández José G. , Higuera Cota María Fernanda F.
Published: June 2022

SMEs, like other organizations, are subject to risk and change in an uncertain environment today more than ever with the economic effects of the COVID-19 pandemic. That is why this study aims to analyze resilience at a strategic level in organizations and the factors that make up organizational resilience. The analysis starts from the assumption that SMEs need to implement a cultural change to respond to crises and disruptions. From a strategic perspective, the chapter provides the concept of organizational resilience, the elements that make it up, and identifies the necessary actions to carry out more flexible and progressive strategies. The study concludes that SMEs require a cultural change, where the main objective is the creation of innovative and creative environments to face crises, through an adaptation and response system based on strategies that consider the resources and capacities of each productive unit.
Cyber Threat Hunting
Authors: Khan Muhammad Salman , Richard Rene , Molyneaux Heather , Cote-Martel Danick , Kamalanathan Elango Henry Jackson , Livingstone Steve , Gaudet Manon , Trask Dave
Published: June 2022

Security and Information Event Management (SIEM) systems require significant manual input; SIEM tools with machine learning minimizes this effort but are reactive and only effective if known attack patterns are captured by the configured rules and queries. Cyber threat hunting, a proactive method of detecting cyber threats without necessarily knowing the rules or pre-defined knowledge of threats, still requires significant manual effort and is largely missing the required machine intelligence to deploy autonomous analysis. This paper proposes a novel and interactive cognitive and predictive threat-hunting prototype tool to minimize manual configuration tasks by using machine intelligence and autonomous analytical capabilities. This tool adds proactive threat-hunting capabilities by extracting unique network communication behaviors from multiple endpoints autonomously while also providing an interactive UI with minimal configuration requirements and various cognitive visualization techniques to help cyber experts quickly spot events of cyber significance from high-dimensional data.
Review of Research on Vision-Based Parking Space Detection Method
Authors: Ma Yong , Liu Yangguo , Shao Shiyun , Zhao Jiale , Tang Jun
Published: June 2022

Parking space detection is an important part of the automatic parking assistance system. How to use existing sensors to accurately and effectively detect parking spaces is the key problem that has not been solved in the automatic parking system. Advances in Artificial Intelligence and sensing technologies have motivated significant research and development in parking space detection in the automotive field. Firstly, based on extensive investigation of a lot of literature and the latest re-search results, this paper divides parking space detection methods into methods based on traditional visual features and those methods based on deep learning and introduces them separately. Secondly, the advantages and disadvantages of each parking space detection method are analyzed, compared, and summarized. And the benchmark datasets and algorithm evaluation standards commonly used in parking space detection methods are introduced. Finally, the vision-based parking space detection method is summarized, and the future development trend is prospected.
Spectrum of histopathological changes and its quantification using a scoring system in patients with gastroesophageal reflux disease
Authors: Thakur Kavita , Varma Kachnar , Bhargava Mudita , Singh Tejasvita , Misra Vatsala , Misra Sri P. , Dwivedi Manisha
Published: June 2022

Aim:

The aim of this study was to evaluate the role of histopathological and histomorphometric features in oesophageal biopsy of patients presenting with symptoms of Gastroesophageal Reflux Disease (GERD).

Material and Methods:

Present study included 42 patients and 12 controls. Complete clinical evaluation followed by endoscopic examination of the patients was done and multipleoesophageal biopsies were taken. Biopsies were processed routinely and stained with Hematoxylin and Eosin and examined for any changes related to GERD. Morphometric assessment was done by using Leitz optical micrometer. The histological scoring was done based on the parameters: basal cell hyperplasia, stromal papillae elongation, cells with irregular nuclear contour (CINC), eosinophilic infiltrate, gastric and intestinal metaplasia. A numerical score was assigned to each parameter and sum of these scores represented the total score.

Statistics:

The statistical analysis was done using graph pad prism, Medcalc software and Windows MS office. P value and mean standard deviation (SD) was calculated.

Results:

The endoscopic findings of all the controls and 83.33% of patients were normal. Only 16.67% of patients had reflux associated changes of varying grades on endoscopy. Oesophageal biopsy of all patients had changes related to GERD on histology. Immunohistochemistry confirmed that cells with irregular nuclear contour were T- lymphocytes. The mean (SD) histological scoring of control and patients were 1.75 (0.62) and 5.66 (1.31) respectively. The difference was considered to be statistically significant (P < 0.001). Thus, it was suggested that a cut-off of histological score > 3 can be used to indicate GERD.

Conclusion:

Patients with gastroesophageal reflux symptoms can have normal endoscopic findings but can be diagnosed on the basis of histological changes in the squamous epithelium. Scoring of the histopathological parameters along with the cut-off value can give a definitive diagnosis of GERD.
Prognostic significance of mast cells and vascular density in prostatic adenocarcinoma
Authors: Das Bismay , Mendonca Susan M.
Published: June 2022

Context:

Though mast cells infiltrate solid tumors, the exact role of mast cells in tumor biology is controversial. Mast cell density (MCD) may vary depending on its location in the tumor and tumor vascularity. MCD may influence the tumor aggressiveness.

Aims:

This study evaluates MCD and tumor vascularity in different histopathological grades of adenocarcinoma prostate.

Settings and Design:

Descriptive study with purposive sampling.

Methods and Material:

The subjects of study were 42 adenocarcinoma patients. 20 cases were of intermediate grade (Gleason score 2–7) and 22 were of high-grade (Gleason score 8-10). Histological diagnosis was made by examining sections stained with hematoxylin and eosin. Additional sections from the same block were stained for mast cells using Giemsa stains as per standard protocol. Mast cell count was done in minimum six random high-power microscopy fields in four different regions- intratumoral, peritumoral, stromal and perivascular regions.

Statistical Analysis Used:

SSPS software version 13.0. Descriptive statistics, Student's t test and ANOVA test.

Results:

In high-grade adenocarcinoma, mast cell counts were higher in perilesional, stromal and perivascular regions, whereas it was lower in intralesional areas as compared to the intermediate grade. However, statistical significance was observed only for the perivascular region. There was significantly higher number of blood vessels in high-grade adenocarcinoma as compared to intermediate grade adenocarcinoma.

Conclusions:

In this study, perilesional mast cells and vascularity increased with increased severity of adenocarcinoma. These findings suggest a possible influence of mast cells on the tumor microenvironment such as vessel density and aggressiveness of tumor. However, further studies are required to substantiate results of this study.
Lucio Phenomenon in a Case of Lepromatous Leprosy
Authors: Musaddique Ansari Saba Mohammed , Zambare Uddhao Suresh , Gupta Ankit , Nayak Chitra Shivanand
Published: June 2022

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae), mainly affecting skin and nerves. Lucio leprosy (LuLp) is a pure primitive diffuse nonnodular form of leprosy. Lucio phenomenon (LP) is a type of necrotizing reaction seen in untreated or inadequately treated cases of LuLp. We present a case of LP in a patient of lepromatous leprosy. A 55-year-old male presented with hemorrhagic bullae, angulated ulcers with jagged margins on lower limbs, purpuric patches on extremities, trunk, and face, and erythematous plaques with intact sensations on back. LP was diagnosed on the basis of clinicohistopathological features.
Profile of Patients Presenting with Deliberate Drug Overdose and Outcome
Authors: Sanjay M , Rabbi Abel S. , Jain Aakriti , Abhilash Kundavaram P. P.
Published: June 2022

Background:

Deliberate self-poisoning (DSP) is one of the leading causes of mortality and morbidity in India. Drug overdose is one of the most common methods for the same and is a growing public health concern globally. It is important to know the spectrum of drugs used for the same and to identify any specific groups at risk.

Methodology:

This retrospective cohort study included patients presenting with medication drug overdose to the emergency department (ED) from January 2017 to December 2018. Patient data were obtained from the ED triage registry software and clinical workstation. Following this, their hospital outcome was determined.

Results:

During the study period, 1802 patients presented with DSP among which drug overdose comprised 27.6% (498/1802). The mean age was 32.8 years (SD-12.6) with a higher incidence in the age group comprising young adults (16–30 years, 52%), majority being females (68%). The most commonly consumed drugs belonged to the drug class of benzodiazepines (22%), NSAIDs (19.2%), antihistamines (15%), antidepressants (12%), and antipsychotics (10.2%). The mortality rate was 0.2%.

Conclusion:

Benzodiazepines were the most commonly consumed class of drugs used for DSP, followed closely by NSAIDs. Drug overdose showed a higher incidence in the age group of highly productive young adults. The incidence exhibited a seasonal pattern with peak in April and May. Although the mortality rate following drug overdose remains low, drug overdose is a commonly used method for DSP and continues to be a growing public health concern.
Degenerate stability of some Sobolev inequalities
Authors: Frank Rupert L.
Published: June 2022

We show that on

\mathbb S^1(1/\sqrt{d-2})\times\mathbb S^{d-1}(1)

the conformally invariant Sobolev inequality holds with a remainder term that is the fourth power of the distance to the optimizers. The fourth power is best possible. This is in contrast to the more usual vanishing to second order and is motivated by work of Engelstein, Neumayer and Spolaor. A similar phenomenon arises for subcritical Sobolev inequalities on

\mathbb S^d

. Our proof proceeds by an iterated Bianchi–Egnell strategy.
Redes sociales, política y Compromiso 2.0: La comunicación de los diputados españoles en Facebook
Authors: Túñez López José Miguel , García José Sixto
Published: June 2022

En una sociedad avanzada tecnológica y sociológicamente las organizaciones que no utilicen los nuevos soportes y técnicas de la comunicación cibernética están previsiblemente abocadas al fracaso. En esta esfera virtual las redes sociales se erigen como un recurso y canal adecuado para la implementación del marketing político 2.0, creando un escenario donde es posible la interacción con los usuarios. Desde esta perspectiva, hemos realizado un seguimiento de los 350 diputados del Congreso de España en Facebook, la red social de mayor audiencia del país, con el objetivo de constatar las presencias y su tipología, frecuencias de actualización, contenidos, recursos utilizados y tipo de información difundida. También se estudia la  interactividad del emisor en lo que conceptuamos como Compromiso 2.0: la comunicación política en entornos personales como las redes sociales exige pasar de la actitud participativa a la acción de participar; es decir, comprometerse con la interacción 2.0 como conducta en la red.
Canine fossa trephine is a beneficial procedure in patients with Samter`s triad
Authors: Seiberling K.A. , Church C.A. , Tewfik M. , Foreman A. , Chang D. , Ghostine M. , Wormald P.J.
Published: June 2022

Background: Canine fossa trephine (CFT) is an adjunctive technique to sinus surgery in patients with recalcitrant maxillary sinusitis. CFT allows for disease clearance in areas of the maxillary sinus that are hard to reach with standard endoscopic techniques. The objective of this study was to compare the surgical outcome of CFT to standard middle meatal antrostomy (MMA) in matched patients with the severely diseased maxillary sinus. Study design: Prospective clinical study Methods: Patients undergoing sinus surgery were enrolled in either the CFT or MMA group. All patients had nasal polyps, Lund Mackay score of 2 in the maxillary sinus, and nasal endoscopy showing the maxillary sinus full of polyps. The patients were followed and the maxillary sinus was graded endoscopically at 3, 6 and 12 months after the surgery. Length of surgery, disease recurrence and need for revision surgery was documented. Results: Forty-two CFTs and MMA were performed in each group. At 6 and 12 months the CFT group demonstrated statistically significant improvement in nasal endoscopy scores. Six patients recurred by the one year mark in the MMA group, 4 of which underwent revision surgery. In the CFT group 2 patients recurred, one who underwent a unilateral revision CFT. Furthermore the CFT did not prolong the surgical time and was often faster than performing a MMA. Conclusion: CFT allows for clearance of all gross disease in the maxillary sinus and appears to improve postoperative outcome at 6 and 12 months and decrease the need for revision surgery.
Antimicrobial and antihelminthic properties of shea butter (Vitellaria paradoxa)
Authors: Nwankwo C. C. , Daodu Bamidele T.
Published: June 2022

The phytochemical, antimicrobial and antihelminthic screening of the crude extract of three types of Vitellaria paradoxa (shea butter) was investigated in this study. The crude extracts were dissolved in di-methylsulfoxide. The phytochemical constituents of the crude extracts were accessed and compared. Clinical isolates under aseptic conditions were collected from the Medical Microbiology Laboratory, University of Port Harcourt Teaching Hospital and further morphological and biochemical tests were carried out to identify this clinical isolates as; Staphylococcus sp., Escherichia sp., Pseudomonas sp., Klebsiella sp., Streptococcus sp and Candida sp. Inoculums were prepared and adjusted to 0.5ml Mc Farland standard of each test bacterium. It was spread onto sterile Muller Hinton Agar plates so as to achieve even growth. The plates were allowed to dry and a sterile cork borer (6.0mm diameter) was used to bore wells in the agar plates. Ofloxacine and Fluconazole was used as bacteria and fungi control respectively. The crude yellow extracts exhibited inhibitory activities that were found to be higher than crude white and ivory colored extract on all the test organisms. Despite the crude yellow extract exhibited higher inhibitory activities than the other extracts; the antibacterial activity was low in 10-1 to 10-4 dilutions for some bacteria. The crude extracts revealed the presence of Alkaloids, flavonoids, Cardiac glycosides, saponnin, and carbohydrates. Anthraquinnone and phlobatannin were absent in the extracts. This study also revealed that shea butter has no anti-helminth effect after 24hours exposure of the eggs of Ascaris lumbricoides and Trichuris trichuria in the shea oil sample rather; the DMSO used as control killed the eggs. This calls for further investigation.
Pattern of immunohistochemical expression of inherited breast cancer genes and collagen changes among African women with early breast cancer in Calabar, Nigeria
Authors: Udonkang Niso , Ugbem Theophilus , Eze Iya , Ofem Esther , Amaka Akom , Johnson Solomon , Onwineng David
Published: June 2022

The disparity in age of diagnosis and genetic testing of breast cancer among African women is a major cause of concern. The common inherited breast cancer genes like breast cancer gene 1 (BRCA1), breast cancer gene 2 (BRCA2) and Tumour protein 53 (TP53 or p53) as well as increase collagen deposition in the stroma predispose women to early breast cancer. The aim of this study was to establish the immunohistochemical expressions patterns of BRCA1, BRCA2, and p53 proteins as well as collagen changes in females with early onset breast cancers in University of Calabar Teaching Hospital. Data on breast tumours occurrences among 96 females were obtained from the Histopathology register. Ten randomly selected paraffin wax-embedded breast tissue blocks from Histopathology laboratory, University of Calabar Teaching Hospital were sectioned at 4 micrometer, stained histologically with haematoxylin and eosin, van Gieson for collagen fibres and immunohistochemically for BRCA1, BRCA2 and p53 protein expressions. Results showed that of the 96 women with breast tumours, 84.4% were ≤50 years while 15.6% were >50 years. Among the 10 tissues, 60% were BRCA1(-) and 40% BRCA1(+), 10% BRCA2(-) with 90% BRCA2(+), and 30% p53(-) with 70% p53(+) for protein expressions, although these were not significant. The BRCA1(+) tissues had significant lower staining intensity than BRCA2(+) (50.5±12.5; p=0.011) and p53(+) (53.8±8.6; p=0.040) counterparts. Majority of the breast tumours had significant increases in collagen fibre sizes consistent with type of tumour and grade of carcinoma but was irrespective of BRCA or p53 statuses. In conclusion, breast tumours are common among women below 50 years in Calabar and the selected early breast cancers were mostly characterized by negative expressions of BRCA1, positive expressions of BRCA2 and p53 proteins as well as increase deposition of collagen fibres. There is urgent need to carryout wider studies on these inherited breast cancer genes and collagen alterations to determine the risk of early breast cancer development.
Trans-orbital sonographic assessment of optic nerve diameter in a sampled Nigerian population
Authors: Udoh Benjamin E. , Paulinus Samson O. , Efanga Samuel A. , Udo-Affah Gabriel U. , Efanga Itoro , Ukpong Ekaete V.
Published: June 2022

Background: Studies have reported variants in the dimensions of optic nerve diameter among different ethnic groups, just as other body anatomy differs from regions to regions.Aim: To establish normal range of optic nerve diameter in a sampled Nigerian population, sonographically.Materials and Method: A total of 725 apparently healthy adult subjects (362 males aged 32 to 65 years and 363 females aged 30 to 68 years) were recruited from the South South and South Eastern parts of Nigeria for this prospective descriptive study. The optic nerve diameter (OND) was measured using a high-resolution digital dedicated small-parts real time ultrasound machine (Sonoace 5500; Medicol, Medison, Miami, FL, USA) with a high frequency (10-MHz) linear array transducer. Subjects were in supine position and were asked to keep their eyes closed and still. Coupling gel was placed on the closed eye lid with the transducer softly placed over the upper temporal eyelid in an axial plane. The OND was measured perpendicular to the vertical axis of the scanning plane as a horizontal distance between the two walls of the nerve sheath. The height and weight of the subjects were determined using a meter rule and a weighing scale.Results: The mean optic nerve sheath diameter of males and females was 4.2 ± 0.13 mm. It ranged from 4.0 to 4.45 mm. The optic nerve sheath diameter of males was not significantly different from that of females (p = 0.345). No significant difference between the mean OND of both eyes (p = 0.345). Body mass index and age did not have any association with OND (r = 0.017, 0.034), the data were normally distributed.Conclusion: Optic nerve diameter of apparently normal Nigerian adults ranges from 4.0 to 4.5 mm. Values outside this range may demand further evaluation in the study population.
Skin carcinogenesis in mice using UVB radiation
Authors: Khanh Nguyen Phuong , Tan Nguyen Hoang , Uyen Le Thi Hoang , Ngan Le Thi Hong
Published: June 2022

Ultraviolet B (UVB) radiation is directly related to sunburn and other visible changes on the skin surface, including discoloration and skin carcinoma. This study investigates the influence of UVB rays (wavelength from 290-320nm) on the formation of cancerous tissues and also shows the differences between abnormal and normal tissue. The mice were stimulated with DMBA chemical protocol and exposure to UVB radiation for skin carcinogenesis. Normal and cancerous skin tissue were stained with Hematoxylin and Eosin, then were measured to obtain optical properties by applying Mueller-Matrix Decomposition, which is considered as an effective skin structure analysis method. Long term exposure to UVB radiation caused skin inflammation and the appearance of crystal bumps. Histopathology results clearly indicate the increasing number of papilloma cells, and prolonged damage by UVB radiation. Skin structural analysis was specified with the optical parameters by Mueller Matrix Decomposition method. The extension of skin carcinoma significantly lessened the values of Linear Birefringence (LB) and Circular Birefringence (CB), as well as the variation of Linear Dichroism (LD) and Circular Dichroism (CD) parameters help validate the differences between normal and squamous cell skin sample.
Cytotoxic activity related to survivin mRNA levels by Combretum quadrangulare Kurz extract against liver and breast cancer cells
Authors: Phuong Nguyen Thi , Huy Duong Thuc , Hung Nguyen Huu
Published: June 2022

Liver cancer and breast cancer have high death rate and increased rapidly in recent years in Vietnam and over the world. Currently, the study of bioactive compounds isolated from plants for killing cancer cells is of interest. Herein, the study aims to identify the cytotoxicity using MTT assay of Combretum quadrangulare Kurz fractions against MCF-7 cells. RT-qPCR method was used to determine the survivin mRNA levels in P12 fraction-treated HepG2 and MCF-7 in comparison to DMSO-treated cells. The results showed that P12 fraction with IC50 of 20.9 ± 0.8 µg/mL was the best cytotoxicity on MCF-7 cells amongst P fractions. P12 fraction exhibited the apoptotic effect on HepG2 and MCF-7 cells by down-regulating survivin expression levels. Thus, P12 fraction was promising for the next research for the impact of fractions assessment in vivo or bioactive compounds isolation.
Determining the risks of the process construction in border areas
Authors: Đat Huynh Tan , Trang Pham Thi Phuong
Published: June 2022

In all phases of the project, there are always events and conditions occurring that directly or indirectly affect the implementation of the project, causing the project to fail to achieve the target of the proposed project subject. Such events and conditions are called project risks. The more human society develops, the more diverse, rich, and complex human activities become. Therefore, risks are increasingly complex and have negative impacts on people’s lives. Construction work is a special product. Therefore there are more and more risks that are hidden in the construction process. Especially when projects are placed in remote, mountainous, or border areas, the risks become more complex and diverse. Hence, if risks are identified quickly and accurately, managers can reduce the level of risk in the process. Then, people can also suggest some solutions to reduce the risks. The goal of this paper is to propose and evaluate the risk factors of the construction process in the border district, Quang Nam Province, by applying the Exploratory Factor Analysis (EFA) method. This study tried to collect data analyze qualitative and quantitative risk factors. The results showed that the collected survey data is meaningful.
Some changes in physiological and biochemical properties of Musa paradisiaca and Musa acuminata AA banana peel during ripening harvested in Tien Giang Province, Viet Nam
Authors: Tat Truong Quoc , Tham Nguyen Thi Ngoc , Khanh Nguyen Duy
Published: June 2022

The objective of this study was to determine some physiological properties (mass ratio, moisture) and biochemical properties (the content of the chlorophyll, carotenoids and the total polyphenol (TPC)) of Musa paradisiaca and Musa acuminata AA banana varieties peel, which were harvested in Tien Giang province, Vietnam at 03 stages of ripeness (I, III and VI in the color index 08 ripeness of banana). The results showed that, the ripening from I to VI maturity had a significant effected on the mass ratio, the moisture, the chlorophyll, the carotenoids and the TPC in 02 banana varieties peel and following different trends. The mass ratio and the moisture decreased, the chlorophyll and the carotenoids content recorded as opposite trends with degradation of chlorophyll and synthesis of carotenoids occured simultaneously, the most specially, the TPC increased and reached to maximum value at III maturity and decreased after. Results suggest that two banana varieties peel could be effectively used for extraction of polyphenol compounds in the future.
Hikmatnoma İçerisinde Yer Alan Halk Hekimliği Unsurları
Authors: ALTUNSOY Sabiha
Published: June 2022

İnsanlar yaşamları boyunca birçok hastalıkla karşılaşmış ve bu hastalıkları sağaltacak yöntemler aramış ya da hastalıkları sağaltmak için bilgisi, yeteneği olan kişilere başvurmuştur. Kimi zaman insanlar bu hastalıkları sağaltmada doğadan yararlanırken kimi zaman da büyü, dua, muska gibi tekniklerden yararlanmışlardır. Sağlıklı hâle geri dönmek veya sağlıklı hâlin korunması için uygulanan bu teknikler, kadim zamanlardan beri var olan ve günümüzde de varlığını devam ettiren halk hekimliğini ortaya çıkarmıştır. Sözlü kültürün ürünlerinden olan, ataların deneyimleri, gözlemleri sonucu ortaya çıkan ve insanı etkileyen birçok unsuru içerisinde bulunduran atasözlerinde halk hekimliğine dair uygulamalar ile sağlıklı kalmak için verilen tavsiyeler kuşaktan kuşağa aktarılarak kullanılmaya devam etmiştir. Konu bakımından zengin bir içeriğe ve bilgi birikimine sahip olan, ustaca kurulmuş, kısa, özlü sözlerin yer aldığı Özbek atasözleri kitaplarında da halk hekimliğine dair unsurlara rastlanılmaktadır. Bu çalışmada Özbek atasözlerinin açıklamalı sözlüğü Hikmatnoma içinde yer alan tıbbi tavsiyeler, halk hekimliği uygulamaları, tedavi amaçlı kullanılan şifalı bitkiler gibi hususlar üzerinde durulmuştur.