bluuebunny/crossref_metadata_2025 huggingface dataset:
Tinjauan Yuridis Pelanggaran Cyber Attack Dalam Perang Modern Berdasarkan Hukum Humaniter Internasional
Authors: Pattiruhu Stenly , Peilouw Johanis Steny Franco , Leatemia Wilshen
Published: March 2023

Introduction: Violations in the form of cyber attacks are carried out by countries that have strong cyber space infrastructure against other countries that have weaknesses in their cyber defense systems.Purposes of the Research: The purpose of this paper is to find out and understand the position of cyber attacks in international humanitarian law and to know and understand the state's responsibility for the use of cyber attacks. Methods of the Research: This type of research is normative juridical where the research is carried out by collecting primary, secondary and tertiary data obtained using library research. The data that has been collected is analyzed qualitatively, the description of which is arranged systematically based on legal disciplines to achieve clarity on the issues to be discussed.Results of the Research: The results of this study indicate that the position of cyber attacks in international humanitarian law is the same as conventional wars based on a cyber attack approach as a war domain as well as attacks in cyber attacks. Cyber attacks also violate the principles of humanitarian law, namely the Principle of Discrimination, the Principle of Proportionality and Uncessary Suffering. Furthermore, with regard to the state having an obligation to be responsible for violations of the principles of International Humanitarian Law caused by cyber attacks carried out by a person or group, it is proven to have a close relationship with the state in accordance with international customs regarding state responsibilities and is also obliged in the responsibilities contained in the law. United Nations Charter. Forms of liability can be in the form of cessation of attacks and reparations. The reparations themselves can be carried out by means of restitution, compensation and giving satisfaction to the victim country.
Peranan Kepala Persekutuan Hukum Adat Sebagai Mediator Di Negeri Hutumuri Dalam Penyelesaian Sengketa Jual Beli Tanah Dati
Authors: Putra Elfransdo Saimima , Matuankotta Jenny Kristiana , Latupono Barzah
Published: March 2023

Introduction: The role of the head of the customary law union as a mediator is to help both parties to the dispute with a family approach.Purposes of the Research: This study aims to identify and explain the role of the Head of the Customary Law Alliance as a mediator in Hutumuri Country in resolving disputes over the sale and purchase of Tanah Dati. Methods of the Research: The research method used is the type of empirical research. The data used in this paper include primary data and secondary data. Techniques Data collection is done by means of field studies and literature studies. Analysis of the materials used in writing this thesis is to use the method of qualitative material analysis.Results of the Research: The results of the study indicate that all problems or disputes related to Dati's land will be resolved at the State Office by the Head of the Customary Law Alliance as a mediator, whose role is to assist the disputing parties by identifying the disputed issues, balancing options, and considering alternatives that can be offered to them. The parties to reach an agreement and only have the authority to provide advice or determine the mediation process in seeking dispute resolution.
Tanggung Jawab Pelaku Usaha Restoran Atas Penyediaan Aksesibilitas Bagi Konsumen Penyandang Disabilitas
Authors: Maisarah Jihan , Kuahaty Sarah Selfina , Pesulima Theresia Louize
Published: March 2023

Introduction: Consumers as users of restaurant services include persons with disabilities who have the right to accessibility. However, the reality is that there are still many restaurants in Ambon city which have not fulfilled their obligation to provide accessibility facilities for persons with disabilities.Purposes of the Research: This study aims to examine the accountability of business actors to consumers and consider resolving disputes between business actors and consumers with disabilities in public services. Methods of the Research: The research method used is normative juridical with a statutory approach in the sources of primary, secondary, and tertiary legal materials.  The technique of collecting legal materials is through library research and prescriptive analysis.Results of the Research: The results of this study show the conditions in order to be able to immediately form actions in supervision and guidance as regulated in Article 29 paragraph (1) and Article 30 paragraph (1) to business actors in public services such as restaurants, to ensure the rights of consumers as regulated in the Law. -Consumer protection law. Enforcement of regulations through legal sanctions so that the fulfillment of consumer rights is truly fulfilled. According to the Consumer Protection Act, it can be in the form of a refund, or by providing compensation in accordance with the provisions of the applicable laws and regulations.
МАҲАЛЛИЙ ДАВЛАТ ҲОКИМИЯТ ОРГАНЛАРИНИ РАҚАМЛИ ТЕХНОЛОГИЯЛАР АСОСИДА БОШҚАРУВ ФАОЛИЯТИНИ ЙЎЛГА ҚЎЙИШ
Authors: Нурмуродов Зафаржон
Published: March 2023

Мақолада маҳаллий давлат ҳокимият фаолиятини рақамлаштириш орқали улар томонидан чиқариладиган қарорлар «Э-қарор» электрон тизими орқали тайёрлаб, қабул қилиш амалиёти йўлга қўйилиши масаласи ёритилган. Бугунги кунда фуқароларнинг ҳуқуқ ва манфаатлари ҳимоя қилинишини, маҳаллий давлат ҳокимияти ва бошқаруви органлари фаолияти очиқлигини, жамоат ва парламент назоратини таъминлаш механизмлари такомиллаштирилиши долзарб масалалардан бири сифатида белгиланди.
THE USE OF PARALINGUISTICS IN JIM BUTCHER'S WORK
Authors: Masharipova Valentina
Published: March 2023

In this article, we explore the use of paralinguistics in Jim Butcher's work, specifically in his popular series, The Dresden Files. Through a comprehensive analysis of various paralinguistic cues used in his writing, we delve into how Butcher creates a rich and immersive reading experience for his fans.
ЯЗЫК - НОСИТЕЛЬ КУЛЬТУРЫ
Authors: Ярматова Мехринисо
Published: March 2023

В этой статье рассматривается, как язык является составной частью культуры. Основываясь на данный материал, можно утверждать, что язык в определенной мере формирует личность его носителя, навязывает заложенное в языке видение мира.
XORIJIY RIVOJLANGAN MAMLAKATLAR VA OʻZBEKISTON QONUNCHILIGIDA MUALLIFLIK HUQUQLARINI JAMOAVIY BOSHQARISHNI SHAKLLANTIRISH TAMOYILLARINING QIYOSIY TAHLILI
Authors: Yakubova Iroda
Published: March 2023

Huquq egalarining tashkilotga aʼzoligi jamoaviy boshqaruv tashkilotini tavsiflovchi muhim elementlardandir. Qolaversa, mualliflik asarlaridan ruxsatisiz foydalanish va mualliflarga mualliflik haqini adolatli toʻlanmatyotganlik holatlarining koʻpligi muallifning mulkiy huquqlarini jamoaviy asosda boshqarish institutini rivojlantirish zaruratining kuchayib borayotganligidan ham dalolat beradi. Maqolada ushbu institutni takomillashtirish bilan bogʼliq ayrim dolzarb muammolarga, shuningdek, Oʻzbekiston va boshqa mamlakatlar olimlarining fikrlariga eʼtibor qaratilgan. Mualliflik huquqini rivojlantirish uchun ilmiy va amaliy ahamiyatga ega boʻlgan taklif va tavsiyalar ilgari surildi.
The 'Bad Behavior Index': A Composite Measure of the Development Hindering Behavior of Individuals and Institutions
Authors: Al Fozaie Mohammad Tariq
Published: March 2023

Composite indices have become a popular tool for providing a quantitative, simplified, and visualized representation of complex phenomena. An example of such is the Human Development Index (HDI) which ranks countries by their level of development. The primary limitation of the HDI is its narrow scope, which hinders its effectiveness at explaining why some nations are more developed than others. The discussion as to why some nations are more developed than others goes back as far as the 14th century, where Ibn Khaldun developed a theory which aims to explain why civilizations rise and fall. Some of the hypotheses which seek to answer this question point to the importance of economic freedoms, absence of corruption, high investment in human capital, and the importance of institutions etc. to development. One hypothesis which has not been properly studied regards the culpability of individual and institutional behavior. The purpose of this study is to introduce a composite measure of the development hindering behavior of individuals and institutions, i.e., the Bad Behavior Index (BBI). The methodology of this study is influenced by the Mazziotta & Pareto framework for composite indices. The index weights have been computed by integrating expert opinion with the Fuzzy Analytic Hierarchy Process (FAHP). The findings of this study suggest that African countries engage in the highest level of bad behavior, which subsequently leads to their poor socio-economic development, whereas Northern countries engage in the least level of bad behavior. The study also finds that the most important drivers for socio-economic development are low levels of corruption, high levels of knowledge creation, strict application of the rule of law, high levels of social cohesion, and high levels of political stability.
Foreign Direct Investment-Growth Nexus in BRICS: How Relevant are the Absorption Capacities?
Authors: Tsaurai Kunofiwa
Published: March 2023

This study examined the impact of foreign direct investment on economic growth in BRICS using fixed effects, dynamic ordinary least squares (DOLS) and fully modified ordinary least squares (FMOLS). Panel data ranging from 1991 to 2019 was used for the purposes of this study. The same study also explored whether financial sector and human capital development are necessary absorption capacities that enhance economic growth in BRICS. To a larger extent, foreign direct investment had a negative impact on economic growth in BRICS, consistent with the dependency theory. Financial development was also found to be the channel through which economic growth is enhanced by foreign direct investment. Although the influence was observed to be non-significantly negative, human capital development improved the influence of foreign direct investment on economic growth. BRICS authorities are therefore urged to implement human capital and financial development enhancement policies to ensure significant foreign direct investment’s positive influence on economic growth.
Методика изучения «закона абсолютного излучения черного тела» в курсах физики академических лицеев
Authors: Саттаркулов К.Р.
Published: March 2023

В статье анализируется совместимость темы излучения абсолютно черного тела с принципом системности курса физики в академических лицеях. На основе современной учебной литературы (учебников, пособий) рассмотрен процесс освещения данной темы, представляющий собой поэтапное углубление и обогащение ее содержания в соответствии с требованиями принципа системности и сделаны соответствующие выводы относительно последовательности в преподавании данного предмета.
Laboratory Medicine and Research in Pathology
Authors: Vidyadaran Sharmili , binti Samsudin Intan Nureslyna , binti Mohd Tohit Eusni Rahayu , Mohd Ali Razana
Published: March 2023

The laboratory is where medicine and science meet. This supplementary issue on ‘Laboratory Medicine and Research in Pathology’ celebrates that partnership. The laboratory study of pathology informs not only diagnosis, but also prognosis and disease pathogenesis. Crucially, a diagnostic test is only as good as its sample and the rigour of its protocol. In this issue, readers can review -20°C and -80°C sample storage of whole blood for HbA1c measurements, analyse the haematological investigations in a rare case of lymphoplasmacytic lymphoma with paraprotein IgG, examine CD14 expression in urothelial bladder carcinoma tissue to correlate inflammation with prognosis, and more. Continuous and looping dialogue between medicine and science, physician and laboratory specialist betters the care of the patient. We hope this series of articles demonstrates that. Sincere thanks to our reviewers and the MJMHS Editorial Board and production team for bringing this special issue to fruition and we hope you enjoy the read.
Prediction of mRNA Targets of miR-101-3p in Diabetic Kidney Disease by Bioinformatics Tools
Authors: Zahari Sham Siti Yazmin , Azwar Shamin , Wai Kien Yip , Ng Chin Tat , Abdullah Maha , Thevandran Kalaiselvam , Osman Malina , Heng Fong Seow
Published: March 2023

Introduction: Diabetic kidney disease (DKD) remains the leading cause of chronic kidney disease (CKD) worldwide. Current biomarkers and treatment still fall short at preventing its progression. In search for a better diagnostic or therapeutic target, much interest in microRNAs, which act as post-translational regulators of gene expression has emerged. An upregulation of miR-101-3p was identified in the sera of type 2 diabetic patients with macroalbuminuria in a selected Malaysian population by profiler RT-PCR array. Using bioinformatics tools, this study aimed to predict the mRNA targets of miR-101-3p. Given the scarcity of bioinformatics studies in DKD, this study also attempted to fill the gap. Methods: The mRNA targets were identified from two experimentally validated databases, namely Tarbase and MirTarBase. The commonly identified mRNA targets were submitted to Metascape and Enrichr bioinformatic tools. Results: A total of 2630 and 342 mRNA targets of miR-101-3p were identified by Tarbase and miRTarbase, respectively. One-hundred ninety-seven (197) mRNA targets were submitted for functional enrichment analysis. Our bioinformatics and bibliographical analyses suggested that ras-related C3 botulinum toxin substrate 1 (RAC1) and Ras-associated protein-1 b (RAP1b) were the most promising putative mRNA targets of miR-101-3p. The most enriched Gene Ontology term and pathway associated with these putative mRNA targets included Ras protein signal transduction and focal adhesion, respectively. Based on these analyses, their molecular mechanisms were proposed. Conclusion: Given the structural heterogeneity of the kidneys and cell type-dependent miRNA modulation, an in-silico target prediction of miR-101-3p increases the probability of a successful future in-vitro experimental verification.
Identification of MYC/BCL2 Double-expressers Lymphomas in Diffuse Large B Cell Lymphoma Patients and Association with their Prognostic Parameters and Survival Rates: A Single Centre Experience
Authors: Ahmad Aliza , Abd Ghani Fauzah , Jaafar Junalina , Abdullah Maizaton Atmadini
Published: March 2023

Introduction: Diffuse large B cell lymphoma (DLBCL) is a heterogenous disease some of which show co-expression of c-MYC and BCL2 and they are known as double expressers (DE) lymphoma. DE lymphoma has been shown to be associated with aggressive clinical course and poor outcome in comparison to those without co-expression. The association of DE lymphomas with their prognostic parameters and the overall survival rate of DE compared to non-DE lymphoma patients were investigated. Method: 66 formalin-fixed paraffin-embedded DLBCL cases were subjected to c-MYC and BCL2 immunohistochemical staining. Results: Out of 66 cases, 25(37.9%) cases showed c-MYC and BCL2 co-expression. Majority of the patients were in age category of ≥ 60 years (68.0%). Male and female distribution were almost equal. DE lymphoma was significantly associated with ABC subtype in comparison to GCB subtype (p= 0.026). Median survival time for DE was 29 months and non-DE was 34 months. Log rank analysis showed there was no significant difference in the overall survival rate of DE and non-DE patients (p=0.401). Conclusion: This study showed significant association between DE lymphomas and ABC subtype. Identification of DE lymphoma with ABC subtype may guide the clinicians in identifying patients with poorer outcome hence a more aggressive treatment may be offered to this group.
CTLA-4 +49A/G And -318 C/T Polymorphisms and Cytokines Level on Inhibitors Development of Haemophilia A among Different Ethnicity in Malaysia
Authors: Nadarajan Anantha Kummar , KN Vaiappuri VS Selvavani , Dato’ Karim Faraizah , Abubakar Suhaili , Md Noor Sabariah
Published: March 2023

Introduction: Haemophilia A (HA) is an inherited X-chromosome recessive disorder characterized by the deficiency of factor VIII (FVIII). About 25-30% of HA patients which received FVIII concentrate developed inhibitors towards FVIII. Ethnicity has been associated as a predisposing factor for the formation of FVIII inhibitors. This study characterizes the polymorphism of +49A/G and -318C/T of Cytotoxic T-Lymphocytes Antigen 4 (CTLA-4) which relates to the development of inhibitors among Malaysian HA patients of Malay, Chinese and Indian ethnicity. Cytokines level of tumour necrosis factor alpha (TNFα), interleukin 4 (IL-4) and interleukin 10 (IL-10) were also measured to assess the link to inhibitors development. Method: Severe HA patients with and without inhibitor who were being treated at the National Blood Centre, Kuala Lumpur were recruited and consented where their collected blood was genotyped for both polymorphisms using the Polymerase Chain Reaction Restriction Fragment Length Polymorphism (PCR-RFLP) and their cytokines levels were measured using the Enzyme-linked Immunosorbent Assay (ELISA). Results: Analysis of the total 64 respondents who fulfilled the study criteria found polymorphisms of CTLA-4 +49A/G and CTLA-4 -318C/T were not significantly different among patients with and without inhibitors. However, HA patients without inhibitors revealed that the Chinese population exhibited a higher +49G allele which is protective towards inhibitors development. Indian patients expressed a higher level of inhibitors titre. Patients without inhibitors showed statistical differences between ethnicity for both genotypes and allele frequencies of CTLA-4 +49A/G (P < 0.05). Conclusion: The mixed pattern of polymorphisms and cytokine profiles were observed in multi-ethnicity. This finding requires further verification with a larger sample size involving multicenter for further confirmation.
Primary Small Cell Neuroendocrine Carcinoma: A Rare Entity of Bladder Neoplasm
Authors: Ahmad Sabri Nadiah , Baba Farahlina , Wan Muhamad Wan Muhamad Mokhzani , Bakrin Ikmal Hisyam , Mat Zin Anani Aila
Published: March 2023

Primary small cell neuroendocrine carcinoma (SCNEC) is a rare high-grade malignant neoplasm with neuroendocrine differentiation derived from the urothelium. Herein, we report a case which presented with symptomatic anaemia secondary to haematuria, complicated with acute kidney injury following obstructive uropathy caused by the SCNEC, along with the discussion of the clinical presentation, radiological imaging and pathological findings of the disease.
Glycated Haemoglobin as an Index of Glycaemic Control: Ethnic Variation among Patients with Type 2 Diabetes Mellitus in a Malaysian Tertiary Hospital
Authors: Arifin Adilah , C. Thambiah Subashini , Abdullah Hafizah , Samsuddin Intan Nureslyna , Zahari Sham Siti Yazmin
Published: March 2023

Introduction: Previous studies have revealed ethnic differences in glycated haemoglobin (HbA1c) value at the same glucose concentration. This study aimed to determine ethnic variation in HbA1c as an index of glycaemic control among type 2 diabetes mellitus (T2DM) patients. Methods: This cross-sectional, retrospective study recruited 293 T2DM patients by simple random sampling at the medical outpatient clinic of a tertiary hospital. Results: Ethnicity was equally distributed with 33.4% Malays and Indians, respectively, and 33.1% Chinese. Significant difference in ethnicity was noted between HbA1c groups ≤6.5% and >6.5%. Indians had the highest median HbA1c (8.3%), followed by Malays (7.7%) and Chinese (7.2%) [p=0.004]. Malays had lower HbA1c compared with Chinese at lower fasting plasma glucose (FPG) whereas Chinese had lower HbA1c compared with Malays at higher FPG, crossing over at FPG 2.8 mmol/L. Indians had higher HbA1c compared with Chinese and Malays except at FPG cross-over of 16 mmol/L where Malays were higher than Indians. FPG and ethnicity were independent predictors of HbA1c. An increase of 1 mmol/L in FPG resulted in an increase of 0.44% in HbA1c. Indians and Malays had 0.60% and 0.47% higher HbA1c, respectively, than Chinese. Conclusion: This pilot study in Malaysia examined ethnic variation in the relationship between FPG and HbA1c among T2DM patients. Since HbA1c is higher in Indians and Malays compared with Chinese at any given FPG, the hypoglycaemia risk may be increased in Indians and Malays when treatment strategies are focussed on using similar target HbA1c values to treat them.
Elucidation of mRNA targets of miR-145-5p in diabetic kidney disease using bioinformatics analysis
Authors: Zahari Sham Siti Yazmin , Azwar Shamin , Wai Kien Yip , Abdullah Maha , Thevandran Kalaiselvam , Osman Malina , Seow Heng Fong
Published: March 2023

Introduction: Diabetic kidney disease (DKD) is a major global cause of end-stage-kidney disease. In view of its ongoing risk of disease progression, the search for a better biomarkers and treatment led to the discovery of microRNAs which regulate gene expression post-translationally. Recently, we reported a trend of upregulation of miR-145-5p in sera of type 2 diabetic patients with macroalbuminuria in a selected Malaysian population, which concurred with previous in vivo and in vitro studies of DKD. In addition, miR-145 has been implicated as a tumour suppressor in various cancers. Methods: In this study, bioinformatics tools were utilized to predict the mRNA targets of miR-145-5p. Results: A total of 683 and 224 experimentally-validated mRNA targets of miR-145-5p were identified by Tarbase and miRTarbase, respectively. Eighty-six (86) commonly identified targets were submitted to Metascape and Enrichr for enrichment analysis. Bioinformatics analysis and literature search suggested that insulin receptor substrate 1 (IRS1) was the most promising target of miR-145-5p. Its associated Gene Ontology terms and pathways included insulin-like growth factor receptor signalling and Forkhead transcription factors (FOXO), respectively. Based on these analyses, the roles of IRS1 in DKD were proposed. Conclusion: As the kidneys are heterogenous in cell types and the mechanism of miRNA is cell-type-dependent, target prediction of miR-145-5p by bioinformatics analysis is particularly important in DKD, to improve the likelihood of a successful in vitro experimental verification in specific renal cell types. In addition, this study attempts to utilize bioinformatics studies, which is not widely done in DKD, as recently reported.
Chapter 15: Teaching for Social Justice in Japan: A Sustainable Model by Gerry Yokota
Authors: Yokota Gerry
Published: March 2023

To clarify our vision for the direction in which we ought to head in the pursuit of the most equitable education for all, it is imperative for us to have a historical perspective on where we have come from and contextualization to analyze how how far we still have to go. The author provides a retrospective view of her career in Japan to aid in that endeavor. Beginning with a reflection on an anti-racist school festival event that occurred in the 1980s, she proceeds to outline how that formative event influenced her development of a sustainable model of course design and implementation for social justice teaching based on the metaphor of the organic farmer: tilling, planting, watering, weeding, and rotating crops. Each metaphorical stage is illustrated with examples of concrete practices, with a focus on the use of music, poetry, and storytelling to inspire active engagement. Yokota concludes with reflections on the significance of two local anti-racist events that took place in 2020 and 2021.
Quraq in the Contemporary Art of Central Asia: Symbolic Language and Artistic Text
Authors: Shaigozova Zhanerke , Ibragimov Aman
Published: March 2023

A piece of fabric and products, made from it, are called quraq by the Kazakhs, in the past and now it occupy a special place in the cultural practice of the peoples of Central Asia; and today its renaissance is taking place in modern art both as an image itself and as an artistic device. This is due to its wide expressive technical and artistic, semantic and communicative capabilities.
In general, authors of the article understand the term of quraq as the traditional patchwork technique as such and the whole variety of products made with this technique. The analysis of modern works of art from the point of view of semiotics showed that a piece of fabric (as a sign and as a symbol) is able to demonstrate various ways of encoding ethnocultural information.
The main methodological tool of this study is the semiotic approach, where a piece of fabric is considered at the level of semantics as a sign of the symbolic language, and from the standpoint of pragmatics as a text representing relationship between the sign (a piece of fabric) and those who use it (an artist, a viewer). The study also uses general scientific methods of observation, comparison, analysis and synthesis. It seems that this approach is relevant in a study of modern visual art.
Based on the semiotic approach and the artistic experience of contemporary artists of Central Asia, this study aims to demonstrate new vectors of Kazakh cultural studies and art criticism.
Concerning the materials used in this article, they come from a variety of sources: the field research carried out by the Russian Ethnographic Museum during the period from 2019 to 2021, a number of regional studies museums in Kazakhstan, as well as online collections of the Central Asian region presented at the International Quilt Museum (Nebraska, USA).
The article has been prepared within the project of the Ministry of Higher Education and Science of the Republic of Kazakhstan AR09259280 Languages of Kazakh Culture as the Basis of Ethnic Identity: Semiotics and Semantics.
Yerel İnternet Haberciliğinde Doğrulama: Okurlara Yönelik Bir Saha Araştırması
Authors: ATA Fırat
Published: March 2023

İnternet ve internet erişim sağlayan teknolojik araçlar, yerel habercilikte hem okur sayısı/profili hem de haberciliğin sınırı açısından yenilikler getirmiştir. Yenilikler ve değişimler yaşanmasına rağmen hem geleneksel hem de internet haberciliğinde önemli ortak konulardan biri haber doğrulama sürecidir. Yerel internet haberciliğinde doğrulama sürecini konu edinen bu çalışma, Hatay ili özelinde gerçekleştirilmiştir. Çalışma, okurların haber doğrulama sürecindeki rolünü tanımlaması açısından önem arz etmektedir. Nicel yöntemin kullanıldığı çalışmada, okurların haber doğrulama sürecindeki rolünü ortaya koyabilmek için Hatay ilinde yedi ilçede 1065 kişinin katılımıyla bir anket çalışması gerçekleştirilmiştir. Elde edilen bulgulara göre, okurların habere güven düzeyi ve haber doğrulama süreci arasında pozitif yönlü bir ilişki söz konusudur. Okurlar, genel olarak güvendikleri haberleri doğrulamakta veya güvenmemesine rağmen ilgili habere yönelik bir doğrulama süreci gerçekleştirmemektedir. Okurlar, içeriğinden şüphe duyduğu haberlerde en çok habercilik dışı araçlara/alanlara yönelmektedir.
Effective ways of using Technology in Teaching
Authors: Mourya Surinder Kumar , Singh Tarandeep
Published: March 2023

During last two decades, technology has evolved and is still evolv ing. Many people are becoming technologically adept and digital citizens.  Technology is essential to the creation and exchange of knowledge in the  teaching sector in the current digital era. When technology is used in the  classroom, it may improve teacher knowledge and aid in the learning and  motivation of the students. Social networking has been used to support  teaching over the past ten years, including its integration with online games  and educational content (Johnson & Germain-Froese, 2016). Technology  has also demonstrated its efficacy in the classroom, serving as a source of  inspiration and creating an environment conducive to real learning. But  there are still drawbacks to using technology in the classroom. Students  might misuse technology and easily become distracted. In addition, exces sive use of technology may impair students’ ability to think (Fetylyana  Nor Pazilah, 2019). This study looked at the best practices for integrating  technology into the classroom. It aims to identify the most efficient online  platforms and technological resources that teachers can use in their line of  work. For creating educational content, many of these tools are free and  simple to use. The purpose of this study is to determine how much aware ness there is among teachers and students at various colleges regarding the  use of technology in the classroom.
Analysis of Marketing Strategies in the context of Green Products
Authors: Jaggi Pallavi , Rini
Published: March 2023

Purpose - In the context of the consumer durables products business,  transformational marketing tactics have been made possible by  the implementation of holistic marketing in the era of Industrial  Revolution 4.0. As a result of customers’ active involvement with  marketers, the range of marketing methods has expanded in line  with consumer knowledge of climate sensitivity, establishing the  groundwork for environmentally friendly products. Green marketing  makes it possible for businesses to create and sell environmentally  friendly goods. Enhancing the company’s reputation, making it  simple to reach a specific consumer group (Niche marketing), and  most crucially, retaining its competitive edge. As consumers become  increasingly conscious of the quality of the items, green products are  intriguing topics to debate. Consumer education about product quality  strives to promote environmental protection and health advantages.  The decision of consumers to purchase green products is influenced by  a variety of factors. In the context of green products in the consumer  durables business, the current study emphasizes the fundamentals  of marketing strategies and related techniques. Consumer durables  encompass anything from FMCG to electronic devices (white and  brown products).
Funding and University Performance: An Econometric Analysis of the Indian Public Universities
Authors: Kaur Amanpreet
Published: March 2023

Underpinning the aim of India’s National Education Policy, 2020 to  devise a performance-based funding mechanism, it is pertinent to  examine the impact of existing financial support on the university’s  performance. Using a fixed panel data analysis, the present study  investigates the influence of funding on the performance of Indian  public universities over the period 2016-2020. The funding is considered  in terms of the plan and non-plan grants received by universities  from the central government, while performance is measured using  performance parameters given by National Institutional Ranking  Framework, 2021. Controlling the age, size and ownership type of  university, findings reveal a significantly positive impact of funding on  teaching performance, research performance and graduation outcomes  of government-owned universities. Surprisingly, university’s outreach,  inclusivity and peer perception have been observed to be indifferent  towards central grants. Overall, the study provides valuable insights to  university practitioners and policymakers for future development of  the performance-funding mechanism.
An Analysis of : Embedded Systems in Embedded Processors Knack
Authors: Talawar Arun K , Malaj Sunita S , Hiremath Raju
Published: March 2023

The mechanisms via way of means of which software program interacts  with the bodily international are converting rapidly. Today’s fashion is  “smart” sensors and drives with microprocessors, community interfaces  and software program that permit far flung get entry to to sensor  records and far flung unit activation. There is likewise the Internet of  Things (IoT), Industry 4.0, Industrial Internet, Machine to Machine,  Internet of Everything, Smart Planet, TSensors (trillions of sensors)  or Fog (similar, however towards the cloud). Earth is an expression of  era that deeply connects our bodily and informational worlds. In the  IoT international, the interfaces among those worlds are stimulated  and derived from statistics era, specially net era. Our recognition  is on interacting with the bodily surroundings wherein software  program and hardware operate. This calls for a unique modeling of  the time dynamics of the software program and networks and a clean  specification of the parallel nature of the application. The truth that  implementation era has now no longer but reached this factor need to  now no longer educate a incorrect technonical approach. All need to  learn design and modeling and enrich them with a critical reflection on  what it is. Today’s embedded systems technology should be presented  in a neutral way, not as a collection of facts and tricks, as in many of  the recent trends in, but as a cornerstone to a better design experience.
Role of Medicinal Plant in the Management of Asthama
Authors: Omkar Dilip Bobade  , Shankar Ashok Dhage  , Nitin B. Kohale  , Suraj B. Rathod
Published: March 2023

Asthma is a common disease that is rising in prevalence worldwide with the highest prevalence in industrialized countries. Asthma affect about 300 million people worldwide and it has been estimated that a further 100 million will be affected by 2025. Since the ancient times, plants have been exemplary sources of medicine. Current asthma therapy lack satisfactory success due to adverse effect, hence patients are seeking complementary and alternative medicine to treat their asthma. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about 45,000 plant species and among them several thousand are claimed to possess medicinal properties. Researches conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for asthma have shown antiasthmatic, antihistaminic and antiallergic activity. This review reveals that some plants and their extract have antiasthmatic, antihistaminic, anticholinergic and antiallergic activity.
Teachers’ Practices and Perceptions of the Flipped Classroom Approach
Authors: Melliti Mimoun
Published: March 2023

Despite the importance of the flipped classroom approach, few studies have investigated its implementations in Tunisia. This study attempts to fill this gap by exploring the different applications of flipped classroom approach, its spread, and its applicability in Tunisia. This study aims to study the Flipped classroom approach’s practices in the English department within the Faculty of Arts and Humanities Kairouan (FLSHK). It also focuses on the English professors’ perceptions regarding this approach. Two research methods were used to collect data; observation of five English classes and interviews with nine FLSHK English professors. This research is of great value in understanding Tunisian professors’ perceptions of the flipped classroom and its applications within Tunisian English classrooms to seek better learning experiences. The findings have significant implications on teaching, teachers, and learners’ experiences.
StartUPV 10 años de ecosistema emprendedor universitario
Authors: Griol Barres Israel
Published: March 2023

StartUPV cumple 10 años. Una década de éxitos, emprendimiento y fomento de grandes ideas. Desde el vicerrectorado de Estudiantes y Emprendimiento queremos no solo seguir apostando por este ecosistema emprendedor,sino dotarlo de más recursos y sinergias para que siga siendo un referente a nivel internacional entre los programas universitarios de formación, incubación y aceleración de startups.Estas páginas incluyen una amplia variedad de historias que muestran como StartUPV ha impactado en la vida de los estudiantes y egresados de nuestra Universitat
La recreación del color de Érase una vez...
Authors: Berriatúa Luciano , Benavides Isabel
Published: March 2023

Para la animación española, 2022 ha sido celebrado como el año del reestreno de un filme prácticamente perdido y olvidado, aunque singular para su historia: Érase una vez…, largometraje dirigido por José Escobar y Alexandre Cirici Pellicer, que llevaba al cine la versión de La Cenicienta descrita por Charles Perrault. Su producción no solo supuso un esfuerzo ímprobo para el tejido industrial y artístico de la animación española, sino que padeció el sino de competir con La Cenicienta disneyana, obligando el llamado mago de Burbank a cambiar el título de la versión española. En las siguientes páginas, Luciano Berriatúa e Isabel Benavides, protagonistas de la recuperación del filme, narran los detalles de un arduo proceso que duró siete años, comprendiendo diferentes técnicas y procedimientos para aproximarse con rigor a la verdad histórica de Érase una vez…
СПОСОБИ ВЧИНЕННЯ КОНТРАБАНДИ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Барган Сергій Сергійович
Published: March 2023

Внаслідок запровадження в Україні правового режиму воєнного стану чинне законодавство з питань митної справи зазнало чималих змін в частині митного оформлення різних груп товарів, спростивши певні митні процедури під час проходження митного контролю і митного оформлення. Поступове наростання кризових явищ через активні бойові дії та стрімке скорочення темпів економічного зростання сприяли збільшенню кількості випадків переміщення через митний кордон України товарів за допомогою приховування від митного контролю. В цьому плані в межах дослідження здійснено спробу висвітлити сучасні способи вчинення контрабанди, що транспортується морським, повітряним, залізничним або автомобільним транспортом з урахуванням індивідуальних властивостей відповідного виду транспорту. На цій підставі розмежовано спосіб вчинення контрабанди шляхом переміщення товарів поза митним контролем від способу перевезення товарів за допомогою приховування від митного контролю і митного оформлення. Наголошено на провідній ролі суховантажів у вчиненні контрабанди, незважаючи на значні ризики блокування українських портів. Вказано, що в умовах закриття неба для цивільної авіації, контрабанда повітряними суднами втратила свою актуальність. Акцентовано увагу на зростаючій ролі автомобільного транспорту у перевезенні через митний кордон України товарів шляхом їх приховування від митного контролю та митного оформлення. В умовах збройної агресії провідної ролі набуває спосіб ввезення контрабанди через митний кордон України під виглядом гуманітарної допомоги, спрямованої на забезпечення першочергових потреб населення та військовослужбовців відповідно до Постанови Кабінету Міністрів України від 01 березня 2022 року № 174 «Деякі питання пропуску гуманітарної допомоги через митний кордон України в умовах воєнного стану», положення якої звільняють гуманітарні вантажі від застосування заходів нетарифного регулювання зовнішньоекономічної діяльності. Зрештою висловлено думку щодо необхідності здійснення подальших наукових пошуків щодо дослідження способів вчинення контрабанди з метою поступового вдосконалення існуючої системи заходів протидії порушенням митних правил.
ШЛЯХИ РОЗВИТКУ КОНЦЕПЦІЇ БІЗНЕСУ І ПРАВ ЛЮДИНИ В ГОСПОДАРСЬКОМУ ЗАКОНОДАВСТВІ УКРАЇНИ
Authors: Токунова Анастасія Володимирівна
Published: March 2023

У статті було проаналізовано правову природу Керівних принципів ООН з питань бізнесу і прав людини (у роботах їх укладача, Дж. Раггі, Спеціального уповноваженого Генерального Секретаря ООН з питань прав людини та транснаціональних корпорацій та інших суб’єктів підприємницької діяльності щодо теоретичного підґрунтя даних Принципів). Здійснено гіпотезу щодо покладення в основу Керівних Принципів ООН ідеї, східної то концепції «суспільного господарського порядку», розробленої Г. Знаменським у рамках формування теоретичних основ господарського права. Виявлено такі спільні риси, як: вихід за межі усталеного бачення та введення додаткового елемента за для вирішення проблеми, яку неможливо вирішити в межах існуючою «системи координат»; забезпечення універсальності такого елементу та його спрямованість на вирішення ключових питань, чи то регулювання господарських відносин в цілому, чи то регулювання корпоративної поведінки; застосування систематизації та побудова взаємодії між різними складовими того чи іншого предмету, методу, принципу тощо, базуючись на загальному підпорядкуванні чи відсиланні до вказаного вище додаткового елемента. Сформульовано перспективи розвитку концепції бізнесу і прав людини у господарському законодавстві України. Запропоновано нові редакції статей 44 і 49 Господарського Кодексу України. Зокрема, надано пропозиції щодо внесення поваги бізнесу до прав людини до переліку принципів підприємницької діяльності. Cтосовно відповідальності суб'єктів підприємництва, запропоновано визначити, що підприємці зобов'язані не завдавати шкоди довкіллю, не порушувати права людини, права та законні інтереси громадян і їх об'єднань, інших суб'єктів господарювання, установ, організацій, права місцевого самоврядування і держави. Також, вони повинні уникати здійснення або сприяння здійсненню негативного впливу на права людини, який зумовлюється їх діяльністю, та усувати такий вплив, коли він виникає. Нарешті, підприємці повинні прагнути запобігти або зменшити негативний вплив на права людини, який безпосередньо пов’язаний з їх діяльністю, продукцією або послугами через їх господарські відносини, навіть якщо при цьому вони не сприяли настанню такого впливу.
Pembrolizumab (Keytruda)
Authors: CADTH
Published: March 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.

The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.

This review assesses pembrolizumab (Keytruda), 200 mg IV every 3 weeks, or 400 mg IV every 6 weeks.

Indication: In combination with chemotherapy for the treatment of adult patients with locally recurrent unresectable or metastatic triple-negative breast cancer who have not received prior chemotherapy for metastatic disease and whose tumours express PD-L1 as determined by a validated test (CPS ≥ 10).
MODERN ASPECTS OF DIAGNOSTICS OF THYROID NODULES
Authors:   Belarusian State Medical University, N. N. Chur , G. G. Kondratenko ,   Belarusian State Medical University, S. U. Yakubouski ,   Belarusian State Medical University, A. P. Vasilevich ,   Belarusian State Medical University
Published: March 2023

Modern information on the problem of thyroid nodules is represented. The main diagnostic methods are discussed. The characteristic of the thyroid nodule, multinodular process and goiter is given. It is noted that inadequate pre- and intraoperative diagnostics, incorrect interpretation of research results often lead to inadequate scope of surgical intervention and unsatisfactory long-term results of treatment. One of the main conclusions is the search for new, more informative and safer methods for diagnosing the nature of thyroid nodules, which is crucial in choosing a treatment method that is adequate to the extent of the operation.
THE PROBLEM OF DIABETES IN THE TREATMENT OF VERTEBRAL INFECTION
Authors:   Vitebsk State Order of Friendship of Peoples Medical University, A. V. Kornilov , M. V. Kuncevich ,   Vitebsk State Order of Friendship of Peoples Medical University, D. S. Alexeev ,   Vitebsk State Order of Friendship of Peoples Medical University, Z. V. Kornilova ,   Vitebsk State Order of Friendship of Peoples Medical University, V. Yu. Zemko ,   Vitebsk State Order of Friendship of Peoples Medical University
Published: March 2023

The study included 88 patients with vertebral infection (nonspecific spinal osteomyelitis – M46.3, spinal epidural abscess – G06.1), of which 24 (27.3%) had diabetes. If the patient had impaired glucose metabolism, the lethality increased by 3.9 times. A key factor in the development of severe neurological deficit in patients with vertebral infection was the combination of epiduritis and diabetes. With the help of cluster analysis, it was found that the highest mortality (45%) is observed in patients who, in addition to the inflammatory focus in the spine, had diabetes, coronary heart disease and nephropathy.
RESULTS OF ELECTROPUNCTURE TESTING IN PATIENTS WITH SALIVARY STONE DISEASE
Authors:   Belarusian State Medical University, I. O. Pohodenko-Chudakova , K. Yu. Slizhykovz ,   Belarusian State Medical University
Published: March 2023

The aim of the study was to determine the informative value of electropuncture testing in patients with salivary stone disease. Objects and methods. The study was performed at the clinical bases of the Department of Surgical Dentistry of the educational institution "Belarusian State Medical University". Using electropuncture testing, 74 patients aged 2558 years (the main group) with diagnosis of salivary stone disease of the submandibular salivary gland were examined. The control group was represented by 30 practically healthy persons. The data obtained during the survey were subjected to statistical processing using the application software package "Statistica 10.0". At the end of the study, the diagnostic effectiveness of electropuncture testing was determined. Results. Functional deviations of auricular points corresponding to the function of the endocrine glands, kidneys – 46%, and the excretory system – 30% were determined in 41% of patients. In 3% of patients, there were no changes in these systems and organs that can affect the metabolic processes of the body. In addition, 3% of the patient had significant functional abnormalities in organ systems that did not affect metabolic processes. Conclusion. Electropuncture testing has a diagnostic efficiency of 98% in the analysis of organs and systems responsible for and involved in metabolic processes in patients suffering from salivary stone disease and allows at least 49% of observations to reliably (for two or more interested organ systems) identify metabolic disorders in individuals of this category which is an indirect confirmation of one of the links in the pathogenesis of the disease under study.
sujidades implexas do urbanismo
Authors: Rosin Maíra
Published: March 2023

Criado em 1935, na gestão de Fábio Prado na prefeitura de São Paulo, o Departamento de Cultura, dirigido por Mário de Andrade, abarcava diversas relações com a cidade, entre elas a dos Divertimentos Públicos. A área não só era de interesse do Departamento, como também interferiu diretamente nas relações urbanas e no combate à prostituição junto à Polícia de Costumes. Este artigo pretende, portanto, trazer luz a essas interferências e aos desdobramentos da divisão de Divertimentos Públicos após a saída de Prado da prefeitura.
Paulo Mendes da Rocha: existência como projeto
Authors: Rios Maira , Viegas Fernando
Published: March 2023

O texto comenta a obra de Paulo Mendes da Rocha por meio do projeto para a Pinacotec do Estado.
Arquitetura como resistência: Autoprodução da moradia popular no Maranhão
Authors: Lago Burnett Frederico , Pereira de Souza Clara Raissa , Moniz Filho Manoel Fernando
Published: March 2023

Perante o agravamento das condições de vida dos despossuídos e das limitações das políticas habitacionais, a autoconstrução persiste como alternativa nacional para a moradia popular. Estudando diferentes grupos sociais em assentamentos populares rurais e urbanos do Maranhão, pesquisa recente constatou que, diferentemente dos procedimentos padronizados do Estado, os processos construtivos populares consideram estrutura familiar, formas de ocupação da terra, práticas produtivas e acesso à renda. Ao exigir capacidade de gerenciamento e resultando em contribuições arquitetônicas significativas para os modos de morar dos que vivem sob adversidades, tais práticas representam exercícios de autonomia e resistência dos despossuídos na qualificação dos seus espaços de vida e afirmação de desejos e capacidades.