bluuebunny/crossref_metadata_2025 huggingface dataset:
Sleep, Internalizing Problems, and Social Withdrawal: Unique Associations in Clinic-Referred Youth With Elevated Sluggish Cognitive Tempo Symptoms
Authors: Rondon Ana T. , Hilton Dane C. , Jarrett Matthew A. , Ollendick Thomas H.
Published: February 2018

Objective: We compared clinic-referred youth with ADHD + sluggish cognitive tempo (SCT; n = 34), ADHD Only ( n = 108), and SCT Only ( n = 22) on demographics, co-occurring symptomatology, comorbid diagnoses, and social functioning. Method: In total, 164 youth (age = 6-17 years, M = 9.97) and their parent(s) presented to an outpatient clinic for a psychoeducational assessment. Between-group analyses and regressions were used to examine study variables. Results: SCT groups were older and exhibited more parent-reported internalizing problems, externalizing problems, sleep problems, and social withdrawal on the Child Behavior Checklist. No significant differences emerged between groups on the Teacher Report Form. Regression analyses involving multiple covariates revealed that SCT symptoms were uniquely related to social withdrawal but not general social problems. Conclusion: Based on parent report, SCT symptoms have a unique relationship with internalizing problems, sleep problems, and social withdrawal. Future research should explore correlates of SCT in youth using multiple informants.
Theory, social work methods and participation
Authors: Lub Vasco
Published: February 2018

This paper examines the use of theory in social work methods geared towards promoting participation of vulnerable groups, a subject that has been barely – if at all – researched empirically. The study comprised an analysis of 46 methods documented in the database of the Netherlands Institute for Social Development and interviews with social workers and educators.

Findings

Social work methods for participation are interspersed with theoretical notions. While the study shows that there is no shortage of theories in this field, what is more problematic are their use and integration. Incorporating theories in such a way that they provide an underpinning of the work method poses a challenge. Many theories appear to be presented out of window dressing, deviate from their original source in the literature, or are narrow in their paradigmatic focus, overlooking alternative theories that could promote or offer better nuanced participation perspectives.

Applications

The paper proposes criteria for a ‘theoretical underpinning’ and provides suggestions for a proper use of theory in social work methods.
“A paradigm of possibility”: Community mentors and teacher preparation
Authors: Cipollone Kristin , Zygmunt Eva , Tancock Susan
Published: February 2018

In this paper, we investigate mentor perspectives of their roles as de facto “teacher educators.” Drawing upon three years of qualitative data, we argue that community voices and knowledge should be reflected in decisions regarding what and how children are taught. We assert that, by broadening the definition of “teacher educator” beyond university faculty to include community members, we create spaces through which the development of culturally responsive teaching can more authentically emerge. The larger study from which this paper is derived examines the innovative practices of a teacher preparation program at a Midwestern university in the United States of America, wherein majority White, female, middle-class candidates are paired with mentor families in a low-income African-American neighborhood. This program of cultural immersion builds relational ties between community members, and mentors facilitate candidates’ movement beyond deficit perspectives of communities of color and simplistic notions of celebration to see cultural affirmation and contextual knowledge of children’s lived experiences as critical to student success. In the present study, we challenge neoliberal “commonsense” in the preparation of teachers by privileging community voices and highlighting how mentors perceive their respective roles as teacher educators.
Analysis of Iliac Artery Geometric Properties in Fenestrated Aortic Stent Graft Rotation
Authors: Doyle Matthew G. , Crawford Sean A. , Osman Elrasheed , Eisenberg Naomi , Tse Leonard W. , Amon Cristina H. , Forbes Thomas L.
Published: February 2018

Introduction:

A complication of fenestrated endovascular aneurysm repair is the potential for stent graft rotation during deployment causing fenestration misalignment and branch artery occlusion. The objective of this study is to demonstrate that this rotation is caused by a buildup of rotational energy as the device is delivered through the iliac arteries and to quantify iliac artery geometric properties associated with device rotation.

Methods:

A retrospective clinical study was undertaken in which iliac artery geometric properties were assessed from preoperative imaging for 42 cases divided into 2 groups: 27 in the nonrotation group and 15 in the rotation group. Preoperative computed tomography scans were segmented, and the iliac artery centerlines were determined. Iliac artery tortuosity, curvature, torsion, and diameter were calculated from the centerline and the segmented vessel geometry.

Results:

The total iliac artery net torsion was found to be higher in the rotation group compared to the nonrotation group (23.5 ± 14.7 vs 14.6 ± 12.8 mm−1; P = .05). No statistically significant differences were found for the mean values of tortuosity, curvature, torsion, or diameter between the 2 groups.

Conclusion:

Stent graft rotation occurred in 36% of the cases considered in this study. Cases with high iliac artery total net torsion were found to be more likely to have stent graft rotation upon deployment. This retrospective study provides a framework for prospectively studying the influence of iliac artery geometric properties on fenestrated stent graft rotation.
Contemporary best practice urolithiasis in pregnancy
Authors: Valovska Marie-Therese I. , Pais Vernon M.
Published: February 2018

Urolithiasis is the most common nonobstetric complication in the gravid patient. The experience can provoke undue stress for the mother, fetus, and management team. The physiologic changes of pregnancy render the physical exam and imaging studies less reliable than in the typical patient. Diagnosis is further complicated by the need for careful selection of imaging modality in order to maximize diagnostic utility and minimize obstetric risk to the mother and ionizing radiation exposure to the fetus. Ultrasound remains the first-line diagnostic imaging modality in this group, but other options are available if results are inconclusive. A trial of conservative management is uniformly recommended. In patients who fail spontaneous stone passage, treatment may be temporizing or definitive. While temporizing treatments have classically been deemed the gold standard, ureteroscopic stone removal is now acknowledged as a safe and highly effective definitive treatment approach. Ultimately, a multidisciplinary, team-based approach involving the patient, her obstetrician, urologist, radiologist, and anesthesiologist is needed to devise a maximally beneficial management plan.
A Cross-Sectional Assessment of Cutaneous Lumbosacral and Coccygeal Physical Examination Findings in a Healthy Newborn Population
Authors: Aby Janelle , Kim Juliann Lipps
Published: February 2018

Objective. The purpose of this study is to describe the range and frequency of cutaneous lumbosacral and coccygeal findings encountered during the newborn examination in a population of apparently healthy babies, to determine if the prevalence of these findings is associated with race/ethnicity, and to report the frequency of co-occurrence of low-risk cutaneous findings. Methods. Lumbosacral physical findings of 1121 infants were documented on well newborns at least 35 weeks or greater gestational age under the authors’ care. The overall frequency of each physical finding was tabulated in addition to determining whether frequencies varied by race/ethnicity. Co-occurrence of the most common physical findings was also examined. Results. Of 1096 infants included in the study, 24.8% had deviated or duplicated gluteal creases, 15.6% had dimples, and 24.7% had lumbosacral and/or coccygeal hairiness. All racial/ethnic groups had double to quadruple the risk of lumbosacral hair when compared with Caucasians. A total of 44.1% of study infants had lumbosacral/coccygeal slate-grey patches, which were least common in Caucasians. Seven infants had coccygeal skin tags, and 14 infants had lumbosacral vascular macules. Thirty-one percent had more than 1 cutaneous lumbosacral finding present, 24.8% had 2 findings, and 6.2% had 3 or more findings. Conclusion. Coccygeal dimples, increased lumbosacral and/or coccygeal hair, deviations and/or duplications of the gluteal crease, and lumbosacral slate-grey patches are common in healthy newborns and vary by race/ethnicity. Eleven percent of study infants had 2 or more low-risk cutaneous findings excluding slate-grey patches. Distinction between low-risk and common versus high-risk findings is important when deciding which patients need further evaluation.
Power, Dominance, and Constraint: A Note on the Appeal of Different Design Traditions
Authors: Rouder Jeffrey N. , Haaf Julia M.
Published: February 2018

The recent field-wide emphasis on power has brought the number of participants used in psychological experiments into focus. Social psychology typically follows a tradition in which many participants perform a small number of trials each; in psychophysics, the tradition is to include only a few participants, who perform many trials each; and the tradition in cognitive psychology falls in between, balancing the number of participants and trials. We ask whether it is better to add trials or to add participants if one wishes to increase power. The answer is straightforward—greatest power is achieved by using more people, and the gain from adding people is greater than the gain from adding trials. In light of these results, the design parameters in the social psychology tradition seem ideal. Yet there are conditions in which one may trade people for trials with only a minor decrement in power. Under these conditions, the limiting factor is the trial-to-trial variability rather than the variability across people in the population. These conditions are highly plausible, and we present a theoretical argument as to why. We think that most cognitive effects are characterized by stochastic dominance; that is, everyone’s true effect is in the same direction. For example, it is plausible that when performing the Stroop task, all people truly identify congruent colors faster than incongruent ones. When dominance holds, small mean effects imply a small degree of variability across the population. It is this degree of homogeneity, the consequence of dominance, that licenses the design parameters of the cognitive psychology and psychophysics traditions.
How I treat myelodysplastic syndromes of childhood
Authors: Locatelli Franco , Strahm Brigitte
Published: February 2018

Pediatric myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal disorders with an annual incidence of 1 to 4 cases per million, accounting for less than 5% of childhood hematologic malignancies. MDSs in children often occur in the context of inherited bone marrow failure syndromes, which represent a peculiarity of myelodysplasia diagnosed in pediatric patients. Moreover, germ line syndromes predisposing individuals to develop MDS or acute myeloid leukemia have recently been identified, such as those caused by mutations in GATA2, ETV6, SRP72, and SAMD9/SAMD9-L. Refractory cytopenia of childhood (RCC) is the most frequent pediatric MDS variant, and it has specific histopathologic features. Allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of choice for many children with MDSs and is routinely offered to all patients with MDS with excess of blasts, to those with MDS secondary to previously administered chemoradiotherapy, and to those with RCC associated with monosomy 7, complex karyotype, severe neutropenia, or transfusion dependence. Immune-suppressive therapy may be a treatment option for RCC patients with hypocellular bone marrow and the absence of monosomy 7 or a complex karyotype, although the response rate is lower than that observed in severe aplastic anemia, and a relevant proportion of these patients will subsequently need HSCT for either nonresponse or relapse.
The ratio of ADSCs to HSC‐progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem‐cell therapy
Authors: Kilinc Mehmet Okyay , Santidrian Antonio , Minev Ivelina , Toth Robert , Draganov Dobrin , Nguyen Duong , Lander Elliot , Berman Mark , Minev Boris , Szalay Aladar A.
Published: February 2018

Background

Stromal vascular fraction (SVF) represents an attractive source of adult stem cells and progenitors, holding great promise for numerous cell therapy approaches. In 2017, it was reported that 1524 patients received autologous SVF following the enzymatic digestion of liposuction fat. The treatment was safe and effective and patients showed significant clinical improvement. In a collaborative study, we analyzed SVF obtained from 58 patients having degenerative, inflammatory, autoimmune diseases, and advanced stage cancer.

Results

Flow analysis showed that freshly isolated SVF was very heterogeneous and harbored four major subsets specific to adipose tissue; CD34high CD45− CD31− CD146− adipose‐derived stromal/stem cells (ADSCs), CD34low CD45+ CD206+CD31− CD146− hematopoietic stem cell‐progenitors (HSC‐progenitors), CD34high CD45− CD31+CD146+ adipose tissue‐endothelial cells and CD45−CD34−CD31−CD146+ pericytes. Culturing and expanding of SVF revealed a homogenous population lacking hematopoietic lineage markers CD45 and CD34, but were positive for CD90, CD73, CD105, and CD44. Flow cytometry sorting of viable individual subpopulations revealed that ADSCs had the capacity to grow in adherent culture. The identity of the expanded cells as mesenchymal stem cells (MSCs) was further confirmed based on their differentiation into adipogenic and osteogenic lineages. To identify the potential factors, which may determine the beneficial outcome of treatment, we followed 44 patients post‐SVF treatment. The gender, age, clinical condition, certain SVF‐dose and route of injection, did not play a role on the clinical outcome. Interestingly, SVF yield seemed to be affected by patient's characteristic to various extents. Furthermore, the therapy with adipose‐derived and expanded‐mesenchymal stem cells (ADE‐MSCs) on a limited number of patients, did not suggest increased efficacies compared to SVF treatment. Therefore, we tested the hypothesis that a certain combination, rather than individual subset of cells may play a role in determining the treatment efficacy and found that the combination of ADSCs to HSC‐progenitor cells can be correlated with overall treatment efficacy.

Conclusions

We found that a 2:1 ratio of ADSCs to HSC‐progenitors seems to be the key for a successful cell therapy. These findings open the way to future rational design of new treatment regimens for individuals by adjusting the cell ratio before the treatment.
Unsupervised seismic facies analysis via deep convolutional autoencoders
Authors: Qian Feng , Yin Miao , Liu Xiao-Yang , Wang Yao-Jun , Lu Cai , Hu Guang-Min
Published: February 2018

One of the most important goals of seismic stratigraphy studies is to interpret the elements of the seismic facies with respect to the geologic environment. Prestack seismic data carry rich information that can help us get higher resolution and more accurate facies maps. Therefore, it is promising to use prestack seismic data for the seismic facies recognition task. However, because each identified object changes from the poststack trace vectors to a prestack trace matrix, effective feature extraction becomes more challenging. We have developed a novel data-driven offset-temporal feature extraction approach using the deep convolutional autoencoder (DCAE). As an unsupervised deep learning method, DCAE learns nonlinear, discriminant, and invariant features from unlabeled data. Then, seismic facies analysis can be accomplished through the use of conventional classification or clustering techniques (e.g., K-means or self-organizing maps). Using a physical model and field prestack seismic surveys, we comprehensively determine the effectiveness of our scheme. Our results indicate that DCAE provides a much higher resolution than the conventional methods and offers the potential to significantly highlight stratigraphic and depositional information.
Importance of Nongovernmental Organizations for the Establishment of a Successful Hematopoietic Stem-Cell Transplantation Program in a Developing Country
Authors: Rivera Franco Monica M. , Leon Rodriguez Eucario
Published: February 2018

Purpose

In low- and middle-income countries with limited resources, the success of a hematopoietic stem-cell transplantation (HSCT) program relies directly on its affordability while obtaining similar outcomes to developed regions. The objective of this study was to describe the experience of a tertiary/referral center in Mexico City performing HSCT with the subsidy of a nongovernmental organization (NGO).

Patients and Methods

We performed a retrospective analysis including 146 patients who underwent HSCT at the National Institutes of Health Sciences and Nutrition Salvador Zubiran and were subsidized by the NGO Unidos.

Results

Seventy-five patients (51%) and 71 patients (49%) underwent autologous and allogeneic HSCT, respectively. The median age was 30 years, 56% did not obtain a bachelor’s degree, 79% had a low socioeconomic level, and 75% were unemployed. None had any health coverage. According to the real patient out-of-pocket expense, the subsidy by Unidos corresponded to 88% and 72% in autologous and allogeneic HSCT, respectively.

Conclusion

Our results highlight that undergoing an HSCT was feasible for vulnerable patients because of the subsidy of medications and chemotherapy by Unidos. Therefore, creating NGOs in developing countries is important to provide complex medical procedures, such as HSCT, at limited-resource centers to underserved populations while obtaining good outcomes.
Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division
Authors: Choudhry Sanjeev Kumar , de Boer Rinse , van der Klei Ida J.
Published: February 2018

Here, we used fluorescence microscopy and a peroxisome-targeted tandem fluorescent protein timer to determine the relative age of peroxisomes in yeast. Our data indicate that yeast cells contain a heterogeneous population of relatively old and young peroxisomes. During budding, the peroxisome retention factor inheritance of peroxisomes protein 1 (Inp1) selectively associates to the older organelles, which are retained in the mother cells. Inp2, a protein required for transport of peroxisomes to the bud, preferentially associates to younger organelles. Using a microfluidics device, we demonstrate that the selective segregation of younger peroxisomes to the buds is carefully maintained during multiple budding events. The replicative lifespan of mother cells increased upon deletion of INP2, which resulted in the retention of all organelles in mother cells. These data suggest that, in wild-type yeast, transport of aged and deteriorated peroxisomes to the bud is prevented, whereas the young and vital organelles are preferably transported to the newly forming buds.
Accuracy and precision of manual segmentation of the maxillary sinus in MR images—a method study
Authors: Andersen Tobias N , Darvann Tron A , Murakami Shumei , Larsen Per , Senda Yurie , Bilde Anders , Buchwald Christian v , Kreiborg Sven
Published: February 2018

Objective:

To assess the accuracy and precision of segmentation of the maxillary sinus in MR images to evaluate the potential usefulness of this modality in longitudinal studies of sinus development.

Methods:

A total of 15 healthy subjects who had been both craniofacial CT and MR scanned were included and the 30 maxillary sinus volumes were evaluated using segmentation. Two of the authors did segmentation of MRI and one of these authors did double segmentation. Agreement in results between CT and MRI as well as inter- and intraexaminer errors were evaluated by statistical and three-dimensional analysis.

Results:

The intraclass correlation coefficient for volume measurements for both method error, inter- and intraexaminer agreement were > 0.9 [maximal 95% confidence interval of 0.989–0.997, p < 0.001] and the limit of agreement for all parameters were < 5.1%. Segmentation errors were quantified in terms of overlap [Dice Coefficient (DICE) > 0.9 = excellent agreement] and border distance [95% percentile Hausdorff Distance (HD) < 2 mm = acceptable agreement]. The results were replicable and not influenced by systematic errors.

Conclusion:

We found a high accuracy and precision of manual segmentation of the maxillary sinus in MR images. The largest mean errors were found close to the orbit and the teeth.

Advances in knowledge:

MRI can be used for 3D models of the paranasal sinuses with equally good results as CT and allows longitudinal follow-up of sinus development.
Quebras, falhas e lentidão no centro de distribuição automatizado da Choc Choc
Authors: Bourguignon Bianca Milli Lucchi , Lucchi Melissa
Published: February 2018

Este caso de ensino relata a modernização da operação logística da Choc Choc. Em 1997, a empresa implantou um Centro de Distribuição (CD) contendo o primeiro armazém vertical automatizado da América Latina. Após 12 anos, o supervisor Pedro Albuquerque enfrenta quebras, falhas em peças e lentidão no sistema. O que Pedro pode fazer para eliminar paradas recorrentes na operação logística do armazém? O caso pode ser utilizado em cursos de pós-graduação em Gestão Empresarial e em Supply Chain, em disciplinas como: Gestão de Operações de Estoque e Armazenagem; Gestão da Informação Aplicada à Distribuição e Transporte; Gestão de Operadores Logísticos/Terceirização. Nomes usados são fictícios. Situação e dados são verídicos.
Prática intercultural da liderança: desafios na organização Rotary
Authors: Vilas-Boas Otacílio Torres , Davel Eduardo
Published: February 2018

Este caso de ensino proporciona uma aprendizagem voltada para o conhecimento das dimensões culturais relacionadas à liderança, para o seu entendimento como expressão intercultural e para a discussão da liderança intercultural a partir da perspectiva da prática. O caso consiste na história de descobertas de João, rotariano – isto é, associado da organização Rotary – que, ao participar de um projeto internacional pela primeira vez, acompanha o trabalho dos líderes, que inclui a formação de parceria, a interação com os rotarianos envolvidos e as comunidades nas quais o projeto é realizado, e a solução de problemas. Com base na experiência vivida por João, é possível conhecer as práticas de liderança no contexto considerado, que estão associadas à presente interação entre culturas. Dessa forma, o caso possibilita que se analise e compreenda de que forma seguidores de diferentes culturas se unem aos líderes, o modo pelo qual líderes conduzem seguidores de diferentes culturas para a realização de objetivos e como são conciliadas as diferenças entre líderes e seguidores de diferentes culturas durante o seu convívio, desafios ligados ao contexto em questão.
Using the care hours per patient day tool: one hospital's experience
Authors: Giannasi Anika , Rudman Josie
Published: February 2018

This article examines one hospital's journey to improve the way in which the nursing workforce was used. A clear message in Lord Carter's review for the Department of Health ( Carter, 2016 ) was to drive efficiency and work towards being the ‘model hospital’. With the introduction of the care hours per patient day, a new rota management system, and a review of the establishment tool used, the hospital has developed a way of real time tracking of nursing time against patient care needs on a ward-by-ward basis. The trust also used a newly developed establishment tool to triangulate and articulate particular patient care requirements.
Never events in the NHS
Authors: Tingle John
Published: February 2018

John Tingle, Associate Professor (Teaching and Scholarship), Nottingham Trent University, discusses the recently revised NHS Never Events policy and framework
Winter pressures and a safety checklist
Authors: Foster Sam
Published: February 2018

Sam Foster, Chief Nurse, Oxford University Hospitals, discusses the Emergency Department Safety Checklist, some of the results after implementation and how it can help with increased emergency department admissions
Perspectiva indigenista en la música metal de Argentina
Authors: Belén Calvo Manuela
Published: February 2018

El indigenismo fue una corriente literaria que se originó en la década de 1920 en Perú y que se desarrolló en varios países andinos, incluso en la Argentina. Aquí la literatura indigenista fue una reacción a los ideales hegemónicos de civilización y barbarie con los cuales se asesinó y sometió a los pueblos originarios. A partir de la década de 1980, gran cantidad de bandas de música metal argentina adoptan esa misma postura. Este artículo tiene como objetivo examinar la forma en que la música metal de Argentina usa una lógica dualista para defender al referente aborigen y condenar al extranjero, utilizando retóricas propias del metal, externas al mundo indígena y provenientes del contexto de la globalización y el capitalismo. Esta reflexión se basa en el análisis sociosemiótico de las producciones de algunas bandas.
Morbo ancestral: Reformulando la cultural local a través de la música metal en Puerto Rico
Authors: Rivera-Segarra Eliut , Varas-Díaz Nelson , Mendoza Sigrid , Díaz Xaymara
Published: February 2018

La integración de la cultura local al metal hecho en Puerto Rico ha ganado interés y atención en las pasadas décadas. Durante la década de los 90 el metal, aún visto como una entidad foránea y estadounidense, integraba la cultura puertorriqueña a su música de forma celebratoria. Esto ha cambiado recientemente y hoy se experimenta una integración temática a través de líricas y arte visual que se distancian de dichas estrategias celebratorias y asumen una perspectiva más crítica sobre la cultura local. El objetivo de este trabajo fue documentar cómo la comunidad metalera de Puerto Rico ha integrado la cultura local al metal de modo crítico mediante una reformulación de los elementos locales. Implementamos un estudio de caso con técnicas de entrevista y análisis de documentos visuales. Aunque usualmente las producciones culturales son recibidas irreflexivamente y de manera celebratoria, recientemente el metal produce música y arte con elementos culturales que critican dicho acercamiento y destacan críticamente el modo en que las producciones culturales también aluden a la morbosidad y a lo oscuro. Examinamos dicha caracterización a través de la figura del vejigante usada en festivales culturales y en las artes plásticas en Puerto Rico. Discutimos el modo en que el metal utiliza la producción cultural como reflejo de un lado oscuro de lo social en Puerto Rico; un tema del cual la mayor parte de la población preferiría no hablar.
Letters, cassette tapes and zines: The circulation of Brazilian heavy metal as a gift system
Authors: dos Santos Silva Melina Aparecida
Published: February 2018

The article addresses cultural exchanges in the Brazilian metal scene and the social practices around materialities such as letters, cassette tapes and fanzines. The exchange of items between headbangers contributed to the globalization of metal and continued over the 1990s and 2000s, in peripheral territories, like Brazil, even with the presence of the Internet. The article is based on a questionnaire administered via social network groups dedicated to Brazilian metal and collectors of cassette tapes and fanzines. The circulation of metal in Brazil is explained from the paradigm of the gift, proposed by Marcel Mauss and others. Our purpose is to highlight the construction of identities and social bonds offered by this cultural exchange.
KUALITAS PELAYANAN PADA KAWASAN WISATA BENTENG KUTO BESAK PALEMBANG
Authors: Sabila Sabrina , Damayanti Maya
Published: February 2018

Benteng Kuto Besak (BKB) that is located in the middle of Palembang is a tourism destination with the main attraction of heritage buildings. Given that, the local government is expecting this area as the main destination in Palembang, it is expected that this destination can provide services that can satisfy visitors. Hence, this research aims to assess the service quality based on visitor perceptionThis research used quantitative descriptive as the method in collecting and analysing data. The results show that the BKB as a whole has satisfied the visitors need, but there are still some services that need to be improved, such as the information and promotion.
DAYA TARIK KAWASAN SOSROWIJAYAN, YOGYAKARTA SEBAGAI KAMPUNG WISATA BAGI WISATAWAN MANCANEGARA
Authors: Permatasari Riska Ardelia , Wahyono Hadi
Published: February 2018

As a tourist city, Yogyakarta has several areas that can become an attraction for international tourists, such as the Sosrowijayan. This area is located in a strategic location with a wide range of accommodation for international tourists. The attractiveness of this area particularly for the international tourists is based on its unique characteristics that have not explored in the previous research. Hence, this research aims to determine the level of attraction and the factors that influence the attractiveness of this area based on the perception of international tourists. This research applied quantitative research methods with questioner in the data collection to examine the tourist perception on the variables of destination attractiveness. This research found that these main factors are comfortability, relaxation, accommodation services, and accessibility.
Konference o jezuitské vědě
Authors: Čornejová Ivana
Published: February 2018

Conference report
A comparative analysis of RAPD and ISSR markers for assessing genetic diversity in Iranian populations of Nigella sativa L.
Authors: Hosseini KorehKhosravi Samira , Masoumiasl Asad , Dehdari Masoud
Published: February 2018

The genetic diversity of 18 Iranian populations of Nigella sativa L. was tested using RAPD (10 primers) and ISSR (12 primers) molecular markers. RAPD primers produced 103 acceptable bands and out of them, 42 bands were polymorphic and the total percentage of polymorphism was estimated 40.5%. Out of the 12 ISSR primers, only 5 of them produced acceptable bands. Five ISSR primers generated 39 amplified products and out of them, 19 bands were polymorphic and the total percentage of polymorphism was estimated 57.4%. As a result, the level of polymorphism obtained from the ISSR markers was higher than of the RAPD markers. Mean of marker index (MI) (0.822 for RAPD and 0.74 for ISSR) and Polymorphic information content (PIC) (0.402 for RAPD and 0.35 for ISSR) for each of the marker systems indicated that both markers were effective for evaluating genetic diversity. Cluster analysis classified the populations into 5 groups for both DNA markers. By integration and analyzing of the two marker systems, the populations were classified into 4 groups. The results of this research showed that RAPD and ISSR molecular markers can be useful for identifying and classifying the Iranian Nigella sativa L. populations.
A new target for the treatment of endometrium cancer by succinic acid
Authors: Iplik Elif Sinem , Catmakas Tolga , Cakmakoglu Bedia
Published: February 2018

Endometrium cancer is the most common invasive gynecologic malignancy in developed countries. Succinic acid (CO2HCH2-CH2CO2H) is a type of dibasic acid that has uncolored crystal. Succinic acid is used in bakery products and aromatized products. It is naturally found in some vegetables. Succinic acid has no adverse effects because it is metabolized by body cells and has a role in the tricarboxylic acid cycle (TCA) as a cycle media component. The TCA cycle and its enzyme components have some crucial roles for basal cell metabolism. Any mistakes, concentration differences in product, or enzyme deficiencies are important within the cell this cycle. In this proposal project, we aimed to investigate the effect of succinic acid at different doses and at different times in an endometrial cancer cell line. The study was performed using methods that determine for apoptosis (for cytotoxicity, WST-1, for caspase enzyme activity, Caspase 3/BCA; apoptotic determination using flow cytometry; Annexin V; to understand mitochondrial membrane potential; JC-1). The results showed that 5 and 10 µM concentration of succinic acid resulted in apoptosis in endometrium cancer; no such effect was seen in the control cell line, which comprised healthy lung cells.  According to our results, it is thought that succinic acid would be effective for the treatment of endometrial cancer cell lines, thus providing new data for other areas of cancer research.
Correlation between serum leptin and its gene expression to the anthropometric measures in overweight and obese children
Authors: Eldosouky Maha K , Abdu Allah Azza M , AbdElmoneim Abeer , Al-Ahmadi Najat Saaeid
Published: February 2018

Obesity is a multifactor disorder with evidence supporting the role of the genetic factor in its etiology. The present study evaluates the relationship between leptin G2548A (rs7799039) and leptin receptors (Gln223Arg (rs1137101) genotyping and its leptin level and the risk of childhood obesity. This case-control study was conducted on 168 overweight and obese Saudi children and 126 non obese one served as control. Fasting insulin, leptin, blood glucose, lipid profile levels were measured. HOMA- IR, and BMI were assessed. Genotyping of leptin and leptin receptor gene variants was done by SNP real-time PCR method. GG genotype and G allele of rs1137101 were significantly higher in overweight and obese children than controls. It showed significant association with risk of obesity OR 7.1 [ 95% CI: 3.4 – 14.8] and OR 2.8 [ 95% CI: 2.0 – 4.1] respectively. Leptin level was significantly greater in patients than controls (p<0.000*) with GG and AG genotypes having the highest level of leptin when compared with another genotype in the obese group. As regards, rs7799039 AA genotype showed significant higher leptin level than other genotypes in the same group with a non-significant difference in genotypes distribution between obese and controls. rs1137101 variant of leptin receptor and fasting leptin level are correlated with overweight and obesity in Saudi children. The GG genotype of leptin receptors rs1137101 and higher serum leptin levels can be used as risk factors for childhood obesity.
Ethanol promotes apoptosis in rat ovarian granulosa cells via the Bcl-2 family dependent intrinsic apoptotic pathway
Authors: Liu Yu , Zuo Haojiang , Wang Yao , Tian Liantian , Xu Xin , Xiong Jingyuan , Pei Xiaofang
Published: February 2018

Excessive and indulgent alcohol consumption causes tremendous public health issues worldwide. Not only is ethanol associated with a broad spectrum of critical chronic diseases, ethanol is also demonstrated to exert striking reproductive toxicity for both males and females. Epidemiological investigations suggested that ethanol is closely related to fertility decrease in women. Animal studies showed that ethanol intake obstructed ovulation and reduced ovarian weight during gestation. However, cellular mechanism for this inhibitory effect of ethanol on female fertility is yet to be explored. This study recruited rat ovarian granulosa cells, the primary effector of ovary, to investigate the effects of ethanol on cell apoptosis and explore potential mechanism. Ovarian granulosa cells treated with ethanol for three hours manifested observable reduction in cell viability and apparent apoptosis. In the presence of 200 and 300 mmol/l of ethanol, the percentages of apoptotic cells increased to 33% and 36%, respectively. In addition, apoptosis related caspase-3 activity was elevated with increasing concentrations of ethanol, suggesting a dose dependent effect. Furthermore, high concentrations of ethanol significantly disturbed the transcriptional and translational regulation of anti-apoptotic Bcl-2 and pro-apoptotic Bax, which are the two key members of Bcl-2 family tightly involved in intrinsic apoptotic pathway. These results indicated that ethanol promotes apoptosis in rat ovarian granulosa cells, possibly via the intrinsic apoptotic pathway.
Problem konstytucyjności art. 68 ustawy o emeryturach i rentach z Funduszu Ubezpieczeń Społecznych w kontekście kontynuacji nauki na studiach doktoranckich
Authors: Mrożek Jakub
Published: February 2018

Artykuł porusza pomijaną w dotychczasowym piśmiennictwie kwestię niedostosowania ustawowej granicy wyznaczającej prawo do renty rodzinnej w stosunku do uczestników studiów trzeciego stopnia (doktorantów). Inicjalnie przedstawiono podstawowe informacje dotyczące renty rodzinnej, ze szczególnym uwzględnieniem okresowego charakteru tego świadczenia, uwzględniając przy tym orzecznictwo Sądu Najwyższego. Następnie zaprezentowano wybrane przykłady ustawowych regulacji zrównujących w prawach i obowiązkach doktorantów ze studentami, jak również tych różnicujących status doktorantów. W dalszej kolejności dokonano kompilacji wcześniejszych tez, zestawiając je z unormowaniami konstytucyjnymi. Szczególny nacisk położono na wyrażoną w ustawie zasadniczej zasadę równości wobec prawa oraz prawa do pomocy socjalnej ze strony państwa, ergo tych regulacji szczególnie rzutujących na omawiany problem. Odwołano się przy tym do dotychczasowego dorobku doktryny oraz orzecznictwa Trybunału Konstytucyjnego. W podsumowaniu zasugerowano zmiany legislacyjne mające za zadanie eliminację zaobserwowanych zastrzeżeń względem Konstytucji RP.
Zalety i wady wprowadzenia systemu ochrony w sektorze banków spółdzielczych w Polsce
Authors: Piechocka-Kałużna Agnieszka
Published: February 2018

Celem niniejszego artykułu jest usystematyzowanie poglądów na temat zalet i wad systemu ochrony (Institutional Protection Scheme) funkcjonującego w sektorze banków spółdzielczych Polsce. Zalety i wady poddano analizie z różnych punkty widzenia, przed i w trakcie jego wdrażania. W artykule zaprezentowano ideę systemu ochrony oraz genezę jego powstania oraz unormowania prawne, w których został on uregulowany. Następnie przedstawiono (z punktu widzenia różnych kryteriów) przegląd zalet i wad systemu ochrony wdrażanego w Polsce. Na podstawie przeprowadzonej analizy dokonano oceny zalet i wad wdrażanego systemu ochrony, a następnie sformułowano wytyczne normatywne w tym zakresie.
O nabyciu użytkowania wieczystego w drodze zasiedzenia. Uwagi krytyczne
Authors: Rozwadowski Władysław
Published: February 2018

Instytucja zasiedzenia, wynaleziona i udoskonalona w prawie rzymskim, przejęta została do większości współczesnych systemów prawa. Do ustawodawstwa polskiego wprowadzona została po raz pierwszy dekretem o prawie rzeczowym z 11 października 1946 r. Dekret ten przewidywał, za kodeksem austriackim, nieznaną prawu rzymskiemu instytucję posiadania prawa, a także możliwość zasiedzenia ograniczonego prawa rzeczowego. Obie możliwości zarzucone zostały w obecnym polskim Kodeksie cywilnym. Jedyny wyjątek stanowi art. 352 k.c. o posiadaniu służebności. Co się tyczy zasiedzenia, to jego przedmiotem może być tylko rzecz materialna znajdująca się w posiadaniu samoistnym dokonującego zasiedzenia. Tu znowu wyjątek stanowi art. 292 k.c. o zasiedzeniu służebności. W roku 1975 Sąd Najwyższy podjął uchwałę o możliwości zasiedzenia użytkowania wieczystego. Sąd ten wyszedł z założenia, że w tym zakresie istnieje luka prawna, a skoro użytkowanie wieczyste jest podobne do prawa własności, można z tego tytułu zastosować analogię wobec użytkowania wieczystego. Obydwa poglądy SN uznać należy za błędne. Utratę użytkowania wieczystego przez długie jego nieużytkowanie przywrócić można z mocy kilku przepisów k.c. Podobieństwa użytkowania wieczystego do prawa własności są niewielkie. Przeprowadzając porównanie tych praw, zaledwie w sześciu przypadkach znaleziono ich podobieństwo, a w osiemnastu istnieją różnice. Nie ma tu także możliwości przyjęcia analogii z art. 292 k.c. Stanowi on bowiem wyjątek, a w myśl już znanej prawu rzymskiemu, a także prawu polskiemu reguły: exceptiones non sunt extendendae. Na podstawie cytowanej uchwały SN w szeregu innych orzeczeń tego Sądu przyjęto koncepcję o istnieniu w prawie polskim możliwości posiadania prawa. Ponieważ w drodze analogii nie można kreować instytucji nieznanej w danym porządku prawnym, uznać należy, że SN wprowadzając możliwość zasiedzenia prawa użytkowania wieczystego, dokonał tego, czego dokonać może wyłącznie ustawodawca.
Zakres i skutki depenalizacji wywołanej nowelizacją przepisu określającego znamiona przestępstwa niealimentacji
Authors: Pohl Łukasz
Published: February 2018

Artykuł dotyczy zakresu depenalizacji wywołanej zmianą art. 209 k.k. i związanej z tą depenalizacją problematyki właściwej wykładni art. 4 § 4 k.k.
Mapa zagrożeń przestępstwami na tle seksualnym jako instrument sytuacyjnej prewencji przestępczości w Polsce – uwagi krytyczne
Authors: Bocheński Maciej
Published: February 2018

Ustawa o przeciwdziałaniu zagrożeniom przestępczością na tle seksualnym została uchwalona 13 maja 2016 r. Przewidziane w jej przepisach instytucje i instrumenty prawne mają przeciwdziałać przestępczości seksualnej. Jednym z wprowadzanych rozwiązań jest mapa zagrożeń przestępstwami na tle seksualnym. O ile sama konstrukcja tego rodzaju narzędzia analizy rozmiarów i fenomenologii przestępczości nie budzi zastrzeżeń z punktu widzenia nauki kryminologii, o tyle wydaje się, że to rozwiązanie w polskim wydaniu jest nieadekwatne do realizacji zamierzonego celu. Artykuł poświęcony jest ocenie polskich rozwiązań w zakresie konstruowania mapy zagrożeń przestępstwami na tle seksualnym w kontekście dorobku i dotychczasowych ustaleń kryminologii środowiskowej, w tym w szczególności nurtu zapobiegania przestępczości przez kształtowanie bezpiecznej przestrzeni oraz sytuacyjnej prewencji przestępczości.
Subaru and Salt Spectroscopy of Chemically Peculiar Hot Subdwarfs
Authors: Jeffery C. Simon , Neelamkodan Naslim , Woolf Vincent M. , Crawford Steven M. , Østensen Roy H.
Published: February 2018

The majority of hot subdwarfs lie on or close to the helium main-sequence. Many have hydrogen-rich surfaces, but a substantial fraction of the hotter subdwarfs have hydrogen-depleted or hydrogen-deficient surfaces. Amongst the former, three were known to show extraordinary overabundances of heavy elements including zirconium and lead. Using Subaru/HDS,we commenced a high-resolution survey of hydrogen-depleted subdwarfs to discover new members of the class. UVO 0825+15, was found to exhibit strong lead lines, to be an intrinsic variable in K2 field 5, and to have a relatively high space motion. Two other lead-rich subdwarfs have been found in the Subaru sample. A much wider survey is in progress using SALT/HRS. Discoveries so far include one extreme helium star similar to V652 Her, and an intermediate helium star with possible comparison to HD144941. Analyses of the hotter and more compact members of the sample are continuing.
HST spectroscopy of chemically peculiar hot subdwarfs: PG 0909+276 and UVO0512–08
Authors: Wild James , Jeffery Christopher Simon
Published: February 2018

High-resolution ultraviolet spectroscopy of two chemically peculiar hot subdwarfs, PG 0909+276 and UVO0512-08, has been obtained using the Hubble Space Telescope. Chemical abundances in the stars’ atmospheres were measured from previous optical spectra and from the new ultraviolet observations. Iron-group metals, including cobalt, copper and zinc, are highly enriched relative to typical subdwarf B (sdB) stars. Lead is also enriched, but with an abundance similar to other sdB stars. The surface chemistry of these two stars is quite distinct from both hydrogen-rich normal sdB stars and also from the intermediate helium-rich sdB stars which show heavy-element superabundances. A full explanation for exotic chemistries in hot subdwarfs remains elusive.
Group actions, non-Kähler complex manifolds and SKT structures
Authors: Poddar Mainak , Thakur Ajay Singh
Published: February 2018

We give a construction of integrable complex structures on the total space of a smooth principal bundle over a complex manifold, with an even dimensional compact Lie group as structure group, under certain conditions. This generalizes the constructions of complex structure on compact Lie groups by Samelson and Wang, and on principal torus bundles by Calabi-Eckmann and others. It also yields large classes of new examples of non-Kähler compact complex manifolds. Moreover, under suitable restrictions on the base manifold, the structure group, and characteristic classes, the total space of the principal bundle admits SKT metrics. This generalizes recent results of Grantcharov et al. We study the Picard group and the algebraic dimension of the total space in some cases. We also use a slightly generalized version of the construction to obtain (non-Kähler) complex structures on tangential frame bundles of complex orbifolds.
Contact manifolds, Lagrangian Grassmannians and PDEs
Authors: Eshkobilov Olimjon , Manno Gianni , Moreno Giovanni , Sagerschnig Katja
Published: February 2018

In this paper we review a geometric approach to PDEs. We mainly focus on scalar PDEs in n independent variables and one dependent variable of order one and two, by insisting on the underlying (2n + 1)-dimensional contact manifold and the so-called Lagrangian Grassmannian bundle over the latter. This work is based on a Ph.D course given by two of the authors (G. M. and G. M.). As such, it was mainly designed as a quick introduction to the subject for graduate students. But also the more demanding reader will be gratified, thanks to the frequent references to current research topics and glimpses of higher-level mathematics, found mostly in the last sections.
Synthesis, physicochemical and catalytic properties of Ni/PrCeZrO catalysts for water-gas shift reaction
Authors: Larina Tatyana V. , Fedorova Yulia E. , Krieger Tamara A. , Ishchenko Arcady V. , Glazneva Tatiana S. , Sadovskaya Ekaterina M. , Eremeev Nikita F. , Sadykov Vladislav A.
Published: February 2018

Mixed nanocrystalline ceria-zirconia oxides doped with praseodymium containing 5, 7.5, 10, and 12.5 wt. % nickel were prepared by the incipient wetness impregnation of the oxide support. Complex physicochemical characterization by X-ray diffraction analysis, ultraviolet-visible diffuse reflectance spectroscopy, high resolution transmission electron microscopy and Fourier-transform infrared spectroscopy of adsorbed CO revealed that the nickelcontaining samples are comprised of a solid solution of praseodymium, cerium and zirconium oxides with the fluorite structure as well as nickel oxide particles with a size up to 100 nm. All prepared nanocomposite catalysts show a high catalytic activity in the water-gas shift reaction. The optimum content of nickel in the catalyst providing the maximum activity was found to be 10 wt. %. A high oxygen mobility in these catalysts estimated by the temperature-programmed oxygen isotope heteroexchange with C18O2 provides required coking stability. To eliminate local overheating of the catalyst and decrease the pressure drop in the reactor, as required for further up-scaling, the active component was supported on a metal plate made of Ni-Al foam alloy. At a fixed contact time, the same level of CO conversion with a fraction of the active component was achieved with an approximately 50 wt% loading on the support.