bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF MINERAL FERTILISERS AND ROOTSTOCKS ON THE GROWTH AND DEVELOPMENT OF THE TROITSKAYA CHERRY TREE VARIETY SEEDLINGS
Authors:   Ural Federal Agrarian Research Center of the Ural Branch of the Russian Academy of Sciences, GALIMOV V.R.
Published: April 2024

The growth and development of fruit crop seedlings depend on various factors that allow increasing the growth and the root collar diameter. The parameters are crucial for obtaining high-quality products. The application of mineral fertilisers allows the plant to fully feed on trace elements throughout the growing season, in conditions when the plant has a limited space for growth but experiences no deficiency in nutrients. Using rootstocks in growing stone fruit trees is critical for the development of seedlings and their resistance to adverse environmental conditions. The variety and rootstock response to mineral fertilisers is another important criterion for obtaining strong cherry seedlings [12, 14]. The Urea mineral fertiliser enhanced the growth of seedlings 1.5-fold on the rootstock of the Ashinskaya and Maak cherry varieties. The fertilisers also increased the root collar diameter: RCD enlarged 1.4-fold on the rootstocks of varieties Ashinskaya and Maaka. The Ashinskaya cherry tree variety has a high regenerative capacity, winter hardiness, rapid growth, high field resistance to pests and diseases [11]. The Maaka cherry tree variety has a monogenic resistance to coccomycosis, high winter hardiness, drought resistance, a high rooting rate of green cuttings and produces no overgrowth. The properties make variety Maaka valuable for rootstock use. The Troitskaya cherry tree variety has an average early ripening period, a high yield, annual fruiting, resistance to pests and diseases, it is a donor of large fruit. The experiment identified the best variant that involved applying the Urea mineral fertiliser at a dose of 5 g / l and, using the Maaka cherry tree variety as a rootstock. The variant demonstrated the highest values for the height of seedlings (68.6 cm) and the highest RCD values (6.9 mm) on average for three years
DEVELOPMENT OF A MODEL OF TRACTION RESISTANCE OF A CULTIVATOR PAW-SHEETER
Authors:   Buryat State Agricultural Academy, named after V.R. Filippova, RADNAEV D.N. , Kalashnikov S.S. ,   Buryat State Agricultural Academy, named after V.R. Filippova, PETROV V.A. ,   Buryat State Agricultural Academy, named after V.R. Filippova
Published: April 2024

The purpose of this work is to develop a mathematical model of the traction resistance in a cultivator share-coulter, which describes the dependence of the energy properties of the seeder on the conditions and mode of operation, characterized by the density and hardness of the soil, the speed of movement and the depth of seed placement. In physical modeling, a real object is characterized as its reduced copy or natural sample, which allows research in laboratory conditions while preserving the nature of the phenomenon. The application of the theory of similarity and dimensions greatly simplifies and makes it easier to determine the functional relationship between the goals of the complexes of quantities that characterize the phenomenon. The article developed a mathematical model of the traction resistance of a cultivator share-coulter with the justification of independent variable factors. The obtained model allows to substantiate the optimal operating parameters, under which the seeder in typical soil conditions has the maximum technological efficiency
NATURAL AND SYNTHESIZED PEPTIDES: COMPARATIVE ANTIMICROBIAL ACTIVITY
Authors:   Ural State Agrarian University, TIKHONOV S.L. , TIKHONOVA N.V. ,   Ural State Agrarian University, CHERNYSHENKO Y.N. ,   Bashkir State Agrarian University
Published: April 2024

A study of the comparative biological activity of a natural antimicrobial peptide isolated from trypsin hydrolysate of cow colostrum and its synthetic analogue was carried out. It was found that the isolated peptide consists of five amino acids and has a molecular weight of 407 Da. According to a search conducted on the Antimicrobial Peptide Database, the isolated peptide has 100 % similarity to the peptide AP01406 obtained from Eisenia foetida and has antiviral, antimicrobial and antitumor effects. The analysis of the chemical and physical properties of the peptide, screening of the results obtained by the Protein NCBI and Antimicrobial Peptide Database databases suggests that the isolated peptide has antimicrobial properties. A threephase synthesis of a natural analog peptide was carried out. It is proved that synthesized and natural peptides have antimicrobial and antifungal activity. The biological activity of the synthesized peptide is slightly higher than the natural one.
REGENERATION OF DWARF PEASHRUB (CARAGANA AURANTIACA KOEHNE) IN PASTURES OF THE INNER TIEN SHAN IN THE SUUSAMYR VALLEY
Authors:   Research Institute of Animal Husbandry and Pastures of the Ministry of Agriculture of thе KR, KENZHEBAEV S.S. , UMANOVA N.D ,   Kyrgyz State Technical University named after I. Razzakov, ABDYRAIMOV A.A. ,   Research Institute of Animal Husbandry and Pastures of the Ministry of Agriculture of Ше KR, KILYAZOVA N.V. ,   Research Institute of Animal Husbandry and Pastures of the Ministry of Agriculture of Ше KR, KERIMALIEV G.K. ,   Research Institute of Animal Husbandry and Pastures of the Ministry of Agriculture of Ше KR, SODOMBEKOV I.S. ,   Chemistry and Phytotechnology NAS of Ше KR
Published: April 2024

Over the past decades, pasture vegetation has been affected by anthropogenic factors in the study area. Poor grazing management and an annual increase in livestock have negatively affected the feed base. In addition, regeneration of ungrazed plant species is revealed. Studies of the experimental plots have established a herbicide impact on Caragana aurantiaca Koehne. The yearly observations show that the above-ground phytomass does not die completely, regrowth from the root and growth of young shoots are recorded
DEPENDENCE OF THE RADIAL GROWTH OF SCOTS PINE TREES ON ENVIRONMENTAL CONDITIONS
Authors:   Bashkir State Agrarian University, IANBAEV R.Y. , Bakhtina S.Y. ,   Bashkir State Agrarian University, Sadykov A.K. ,   Bashkir State Agrarian University
Published: April 2024

The results of a comparative analysis of the annual radial increment in two stands of Scots pine (Pinus sylvestris L.) are presented in the article. One of the trial plots is adjacent to the industrial dumps of the Uchalinsky Mining and Processing Plant, which pollute the environment with a complex of industrial pollutants with copper and zinc dominating among them. A nearby stand with trees without symptoms of direct exposure to industrial pollution was selected as a control. As a reference point for determining the dynamics of annual radial increment, 1959 was chosen when the Uchalinsky quarry began to be actively established. Despite the exposure of the trees on the territory of the plant to significant industrial pollution, a significant and increasing decrease in the values of annual radial growth was not observed among the trees of this trial plot. At the same time, the coefficient of variation of the increment in each year of measurements was consistently lower on this habitat compared to natural conditions. The results obtained were explained by the ecological plasticity of Scots pine and its tolerance to the toxic effects of copper and zinc. The data also prove the necessity of using the species for the natural remediation of industrially polluted territories and the accumulation of heavy metals in biomass of trees.
A NEW APPROACH TO EVALUATING SIRES BY THE OFFSPRING QUALITY
Authors:   Institute of Agriculture – branch of the Kabardino-Balkarian Scientific Center of the Russian Academy of Sciences, GUKEZHEV V.M. , KHURANOV A.M. ,   2Kabardino-Balkarian state agrarian university named after V.M. Kokov
Published: April 2024

The repeatability of the results of evaluating sires by the offspring quality according the conventional methods of daughter-herd (basic) and daughter-dam (clarifying) comparison for production is low and does not always correspond to the assigned categories. The records of evaluating eight sires of different genotypes by the offspring quality based on the daughter-dam comparison for production were investigated. To this end, daughters’ dams were assigned to seven groups by milk yield for 305 days of the first lactation, with a class interval of 500 kg in comparison with the daughter’s milk yield in each group, and the daughter-dam difference for production was established. The second stage involved assigning sires’ daughters, in the same manner, to the similar seven groups, for comparison with dams. The procedure aimed to establish which dams by milk yield produced different groups of daughters; compared with the dams the daughters came from. The proposed method for evaluating sires based on compatibility with the breeding stock of different milk yield classes has several advantages over the conventional method of the daughter-herd comparison. The new approach allows establishing the limits for dams based on the milk yield within which a sire has a significantly improving effect; selecting a class of dams by milk yield that gave birth to the highest-yielding daughters. The method eliminates the need to rank the tested sires as improving, neutral and worsening types with numerous variations and makes it possible for the breeder to set up a plan for selection – assigning dams to a sire. The study suggests the following selection plan of assignment (sires – dams with a milk yield for 305 days of the first lactation): Arzamas 8815 – from 3700 to 4700 kg, Gir 1883 (ceased), Grilyazh 6977 – from 4000 to 4500 kg, Iman 314 – limited to 4000 kg, Knor 45026 – from 4000 to 5000 kg, Twist 76849 – from 3000 to 4500 kg, Tibul 3728 – from 4000 to 5000 kg, and Torpan 2739 – with all classes up to 6001 kg and above.
INFLUENCE OF GRAIN MOISTURE ON THE DISTRIBUTION OF MICROWAVE FIELD FROM SEMICIRCULAR SLOTTED WAVEGUIDES
Authors:   Federal Scientific Agroengineering Center «VIM», VASILYEV A.A. , VASILIEV A.N. ,   Federal Scientific Agroengineering Center «VIM», TIKHOMIROV D.A. ,   Federal Scientific Agroengineering Center «VIM»
Published: April 2024

This article focuses on the utilization of microwave fields in installations for drying, pre-sowing treatment, and grain disinfection to enhance productivity and reduce energy consumption. The study examines the design of semi-circular waveguides with slotted radiators for the uniform distribution of microwave fields in a dense grain layer. Additionally, the research investigates the influence of grain moisture on the efficiency of microwave-convective installations. Using the CST Microwave Studio software, the effect of moisture on the distribution of microwave fields in the grain layer and energy transmission efficiency was investigated. The results showed that as the moisture content of the processed grain increased from 14 % to 26 %, the radiation efficiency decreased by 15.1 %, and the overall radiation efficiency decreased. Moisture variation also leads to changes in the characteristics of radiation efficiency with changes in the magnetron emission frequency.
Effects of Fermentation and Germination on Raw Whole-wheat Grain of Triticum durum in the Evaluation of Its Proximate, Minerals and Antinutrients Composition
Authors: Ilesanmi Adeyeye Emmanuel
Published: April 2024

Background: This work reports on the effects of processing on food composition of Triticum durum grown in Nigeria. Methods: Standard methods were used to determine proximate, minerals and antinutrients levels in raw (RS), fermented (FS) and germinated (GS) samples of T. durum. Results: Protein was enhanced in GS, crude fat in FS and GS whereas fibre was reduced in FS and GS and ash in FS. Water balance for protein metabolism were (ml): RS (579) > FS (576) < GS (630). Mineral reduction due to treatment can be seen as follows (mg/100g): RS (266.6) > GS (242.21) > FS (241.59). Major enhanced minerals during processing: Zn, Mn, and Na. Among the mineral ratios, [K/(Ca+Mg)] had values between 2.96-3.00 which were higher than the reference ideal balance of 2.20. In MSI for Na, Ca, Mg, Zn, Fe and P, only Zn had values greater than standard MSI indicating no deleterious effects in all the samples (except Zn). Processing highly reduced the antinutrients. Enhancement occurred in tannic acid, RS/FS (30.6), RS/GS (14.5), FS/GS (12.3). Significant differences (rc=0.01) existed; pairs RS/FS, RS/GS, FS/GS for proximate, mineral, antinutrient and molar ratios. Conclusion: In the areas of food functionality, importance would be GS > FS > RS.
Symplectic Form yang Berkaitan Dengan Satu-form Suatu Aljabar Lie Berdimensi Rendah
Authors: Kurniadi Edi
Published: April 2024

In this paper, we study symplectic form on low dimensional real Lie algebra. A symplectic form is very important in classifying of Lie algebra types. Based on their dimension and certain conditions, there are two types of Lie algebras. A lie algebra with odd dimension endowed with one-form  such that   is called a contact Lie algebra, while a Lie algebra whose dimension is even and it is endowed with zero index is called a Frobenius Lie algebra. The research aimed to give explicit formula of a symplectic form  of  low dimensional contact Lie algebras and Frobenius Lie algebras. We established that a one-form associated to simplectic form determine a type of a Lie algebra whether a contact or a Frobenius Lie algebras.To clearer the main results, we give some examples of one-form and symplectic form of Frobenius and contact Lie algebras.
Perbandingan Metode Muller dan Metode Newton-Raphson dengan Dekomposisi Adomian yang Dimodifikasi dalam Menyelesaikan Persamaan Polinomial
Authors: Azisah Nurman Try , Mariani Andi , Rahmat Rahmat Nurhidayat
Published: April 2024

Penelitian ini mengkaji mengenai penyelesaian masalah persamaan polinomial dengan membandingkan Metode Muller dan Metode Newton-Raphson dengan Dekomposisi Adomian yang Dimodifikasi menggunakan bantuan program Python berdasarkan nilai akar, nilai galat, dan jumlah iterasi. Persamaan polinomial dalam satu variabel ditetapkan sama dengan nol. Persamaan yang digunakan dalam penelitian ini ialah persamaan polinomial berderajat 5 dan persamaan polinomial berderajat 6. Hasil penelitian menunjukkan bahwa Metode Muller memperoleh nilai akar berbentuk real, iterasi yang lebih banyak dan nilai galat yang masih besar. Sedangkan pada Metode Newton-Rapshon dengan Dekomposisi Adomian yang Dimodifikasi memperoleh nilai akar berbentuk real, iterasi yang lebih sedikit dan nilai galatnya kecil. Dengan demikian, metode terbaik yang dapat digunakan dalam menyelesaikan masalah persamaan polinomial ialah metode Newton-Raphson dengan Dekomposisi Adomian yang dimodifikasi.
Optimization of adaptive capabilities of first-year students majoring in psychology
Authors: Komar Tetiana
Published: April 2024

Важливим завданням сьогодення є підготовка висококваліфікованих фахівців-психологів. Саме фахівці-психологи беруть активну участь у збереженні психічного та психологічного здоров’я населення. Важливо, щоб під час навчання здобувачі спеціальності психологія не тільки мажи можливість набути фахових компетенцій, але й були озброєні практичними навичками самодопомоги та оптимізації адаптаційних можливостей. У науковій статті представлені результати констатувального дослідження особливостей адаптаційних можливостей здобувачів першого курсу спеціальності психологія.За результатами дослідження встановлено, що досліджувані здобувачі першого року навчання спеціальності психологія переважно не вміють задовольняти свої актуальні потреби і реалізувати пов’язані з ними значущі цілі, вони не відчувають себе відповідальними за все, що відбувається з ними в житті і не думають, що здатні впливати на власне життя. Також є можливі проблеми з адекватною самооцінкою, негативна самопрезентація, неадекватний рівень домагань. Однак високий рівень показника самоприйняття свідчить про позитивне ставлення до себе, безумовне прийняття себе таким, яким є, при збереженій самокритичності, що може в сприяти успішній соціально-психологічній адаптації.В той час, одержані показники дослідження свідчать про те, що досліджувані намагаються об'єктивно оцінювати виникаючі ситуації у своєму житті, проте це їм вдається або не відразу, або вони не зовсім впевнені у своїх силах, можливостях та досвіді. Тому можливе порушення емоційної рівноваги та зниження працездатності. В той час наявне переважання високого рівня особистісної тривожності, що свідчить про переживання досліджуваними незадоволеності собою та своїм життям, почуттями невпевненості, сором’язливості, скутості у стосунках, наявності внутрішніх конфліктів. У поведінці орієнтовані на думку оточення, відчувають страх перед критикою та негативною оцінкою зовні. Можливі проблеми з адекватною самооцінкою, негативна самопрезентація і відповідне негативне ставлення до особистого життя та провідної діяльності.За результатами кореляційного аналізу втановлено, що на показник дезадаптивності позитивно впливають такі чинники, як неприйняття себе (0,570), неприйняття інших (0,725), емоційний дискомфорт (0,865), зовнішній контроль (0,804), відомість (0,591), ескапізм (0,632), ситуативна та особистісна тривожність (0,627; 0,651). Зазначені результати дослідження можуть свідчити про те, що показники за шкалами неприйняття себе, неприняття інших, емоційний дискомфорт, зовнішній контроль, відомість та ескапізм взаємозалежні із дезадаптивністю, та провокують її виникнення.Враховуючи результати дослідження, важливо запропонувати досліджуваним здобувачам першого року навчання спеціальності психологія участь у програмі оптимізації адаптаційних можливостей, що значно знизить прояви дезадаптивності та сприятиме розвитку адаптаційного потенціалу особистості.
Методика формування в майбутніх педагогів відповідального ставлення до професійних цінностей
Authors: Волошина Оксана , Пінаєва Ольга
Published: April 2024

The article describes the method of forming a responsible attitude to the system of professional values in future teachers. The essence of a responsible attitude to professional pedagogical activity is manifested in: the future teacher's awareness of the value of his profession, his own place in the professional environment, the formation of motives for professional behavior; the teacher has integrated subject and psychological-pedagogical knowledge, formed professional abilities and skills, experience in the practical implementation of professional activities; skillful organization by the teacher of his activity and effective management of it; the teacher's abilities to analyze pedagogical situations and pedagogical reflection; feelings of satisfaction from the results of pedagogical activity, striving for creative implementation of the teacher's duties and overcoming difficulties on the way to professional development. In the process of teaching the educational disciplines «Pedagogy», «Methodology of educational work», «History of pedagogy», «Fundamentals of pedagogical mastery», the methodology of forming a responsible attitude to the system of pedagogical values in future teachers was introduced. The requirements for the teacher's professional competencies were analyzed on the basis of modern documents on education. We determined the content of the educational material, identified semantic connections between its elements. The development of the procedural component consisted in the study of professional experience, the performance of cognitive and practical tasks. In the process of organizing educational activities, both traditional (lectures, practical, laboratory classes) and interactive (group work, business games, problem-based learning, project method) forms of work were introduced.
Підготовка викладача до здійснення E-навчання в освітньому процесі вищої школи Німеччини
Authors: Лазаренко Наталія , Гапчук Яна
Published: April 2024

У статті розглянуто проблему використання електронного навчання (Е-навчання) у підготовці майбутніх учителів в університетах Німеччини, що є достатньо новим і водночас перспективним напрямом порівняльної педагогіки. Особливо активного розвитку ця проблема набула в останні роки, що значною мірою обумовлено поширенням цифрових форм навчання, котрі були визнані у Німеччині особливою категорією новітніх освітніх технологій. Передбачається, що постійне впровадження нових педагогічних технологій надасть більш широких можливостей для розвитку педагогічних університетів Німеччини та підтримання конкурентоспроможності на міжнародному ринку освітніх послуг. Успішні сценарії Е-навчання враховують необхідні дидактичні умови навчання в різних контекстах, наприклад автентичний або соціальний контексти навчання та забезпечують суттєву цифрову підтримку навчальних матеріалів. Автори розглядають використання цифрових засобів навчання, що має диференційоване представлення та характеризують найбільш розповсюджені види Е-навчання, котрі використовуються у підготовці майбутнього вчителя в Німеччині та охоплюють сучасний спектр розміщення сценаріїв подій та матеріалів лекцій в Інтернеті для повністю віртуального викладання, а саме: комп’ютерне навчання в режимі онлайн, інтернет-навчання, змішане навчання (Blended Learning), виключно віртуальне навчання, дистанційне навчання в Інтернеті. Важливим аспектом Е-навчання є інструменти та медійні засоби реалізації Е-навчання, до яких відносять програмне забезпечення для порталів, систему управління адміністративними функціями (управління персоналом та управління студентами) та управління курсами, навчальною платформою, інструментами для створення та для спільної роботи в мережі. Е-навчання широко використовується в університетах Німеччини, воно підтримує процеси навчання завдяки використанню різних цифрових технологій, що забезпечують виконання операцій різними способами. Викладачам пропонується вибір навчальних сценаріїв викладання та навчання, а резерв електронного семестру спрямований на подальшу підтримку викладання в аудиторіях.
GERMAN RAILROADS, JEWISH SOULS
Authors: Browning Christopher R. , Hayes Peter , Hilberg Raul
Published: April 2024

German Railroads, Jewish Souls centers around Hilberg’s seminal essay of the same name, a landmark study of German railways in the Nazi era long unavailable in English. Supplemented with additional writings from Hilberg, primary source materials, and historical commentary from leading scholars Christopher Browning and Peter Hayes.
THE ANATOMY OF THE HOLOCAUST
Authors: Hilberg Raul
Published: April 2024

Though best known as the author of the landmark 1961 work The Destruction of the European Jews, the historian Raul Hilberg produced a variety of archival research, personal essays, and other works over a career that spanned half a century. The Anatomy of the Holocaust collects some of Hilberg’s most essential and groundbreaking writings―many of them published in obscure journals or otherwise inaccessible to nonspecialists―in a single volume. Supplemented with commentary and notes from Hilberg’s longtime German editor and his biographer.
INSTITUTIONALISED DREAMS
Authors: Drążkiewicz Elżbieta
Published: April 2024

Using examples from Poland, Elżbieta Drążkiewicz explores the question of why states become donors and individuals decide to share their wealth with others through foreign aid. She comes to the conclusion that the concept of foreign aid requires the establishment of a specific moral economy which links national ideologies and local cultures of charitable giving with broader ideas about the global political economy. It is through these processes that faith in foreign aid interventions as a solution to global issues is generated. The book also explores the relationship linking a state institution with its NGO partners, as well as international players such as the EU or OECD.
BECOMING VAISHNAVA IN AN IDEAL VEDIC CITY
Authors: Fahy John
Published: April 2024

Becoming Vaishnava in an Ideal Vedic City centers on a growing multinational community of ISKCON (International Society for Krishna Consciousness) devotees in Mayapur, West Bengal. While ISKCON’s history is often presented in terms of an Indian guru ‘transplanting’ Indian spirituality to the West, this book focusses on the efforts to bring ISKCON back to India. Paying particular attention to devotees’ failure to consistently live up to ISKCON’s ideals and the ongoing struggle to realize the utopian vision of an ‘ideal Vedic city’, this book argues that the anthropology of ethics must account for how moral systems accommodate the problem of moral failure.
IF EVERYONE RETURNED, THE ISLAND WOULD SINK
Authors: Petrou Kirstie
Published: April 2024

Focusing on the small island of Paama, Vanuatu, and the capital, Port Vila, this book presents a rare and recent study of the ongoing significance of urbanisation and internal migration in the Global South. Based on longitudinal research undertaken in rural ‘home’ places, urban suburbs and informal settlements over thirty years, this book reveals the deep ambivalence of the outcome of migration, and argues that continuity in the fundamental organising principles of cultural life – in this case centred on kinship and an ‘island home’ – is significantly more important for urban and rural lives than the transformative impacts of migration and urbanisation.
COLONIAL SEEDS IN AFRICAN SOIL
Authors: Munro Paul
Published: April 2024

“Empire forestry”—the broadly shared forest management practice that emerged in the West in the nineteenth century—may have originated in Europe, but it would eventually reshape the landscapes of colonies around the world. Melding the approaches of environmental history and political ecology, Colonial Seeds in African Soil unravels the complex ways this dynamic played out in twentieth-century colonial Sierra Leone. While giving careful attention to topics such as forest reservation and exploitation, the volume moves beyond conservation practices and discourses, attending to the overlapping social, economic, and political contexts that have shaped approaches to forest management over time.
IN FADING LIGHT
Authors: Leggott James
Published: April 2024

For over five decades, the Newcastle-based Amber Film and Photography Collective has been a critical (if often unheralded) force within British documentary filmmaking, producing a variety of innovative works focused on working-class society. Situating their acclaimed output within wider social, political, and historical contexts, In Fading Light provides an accessible introduction to Amber’s output from both national and transnational perspectives, including experimental, low-budget documentaries in the 1970s; more prominent feature films in the 1980s; studies of post-industrial life in the 1990s; and the distinctive perils and opportunities posed by the digital era.
BEYOND WILD AND TAME
Authors: Oehler Alex C.
Published: April 2024

Responding to recent scholarship, this book examines animal domestication and offers a Soiot approach to animals and landscapes, which transcends the wild-tame dichotomy. Following herder-hunters of the Eastern Saian Mountains in southern Siberia, the author examines how Soiot and Tofa households embrace unpredictability, recognize sentience, and encourage autonomy in all their relations with animals, spirits, and land features. It is an ethnography intended to help us reinvent our relations with the earth in unpredictable times.
Periprocedural intravenous heparin in patients with acute ischemic stroke treated with endovascular thrombectomy after intravenous thrombolysis
Authors: Wang Hao , Yuan Kang , Huang Xianjun , Zhong Yi , Xie Mengdi , Ye Ruidong , Han Yunfei , Lv Qiushi , Zhao Qingshi , Liu Rui
Published: April 2024

OBJECTIVE

The benefit-to-risk ratio of periprocedural heparin in patients treated with endovascular thrombectomy (EVT) after intravenous thrombolysis (IVT) remains unclear. This study aimed to evaluate the potential effects of periprocedural heparin on clinical outcomes of EVT after IVT.

METHODS

The authors retrospectively analyzed patients from multicenter studies treated with EVT after IVT in the anterior circulation. The endpoints were unfavorable outcome (defined as modified Rankin Scale score ≥ 3 at 90 days), 90-day mortality, symptomatic intracranial hemorrhage (SICH), successful recanalization, and early neurological deterioration. Patients were divided into two groups based on whether they were treated with heparin (heparin-treated group) or not (untreated group), and the efficacy and safety outcomes were compared using multivariable logistic regression models and propensity score–matching methods.

RESULTS

Among the 322 included patients (mean age 67.4 years, 54.3% male), 32% of patients received periprocedural heparin. In multivariable analyses, the administration of periprocedural heparin was a significant predictor for unfavorable outcome (OR 2.821, 95% CI 1.15–7.326; p = 0.027), SICH (OR 24.925, 95% CI 2.363–780.262; p = 0.025), and early neurological deterioration (OR 5.344, 95% CI 1.299–28.040; p = 0.029). Regarding successful recanalization and death, no significant differences between the groups were found after propensity score matching.

CONCLUSIONS

The results showed that periprocedural heparin is associated with an increased risk of unfavorable outcomes and SICH in patients treated with EVT after IVT. Further studies are warranted to evaluate the utility and safety of periprocedural heparin.
Aspects canoniques de la non-dissolution du marriage
Authors: Петренко Глеб Викторович
Published: April 2024

Данная статья посвящена вопросу нерасторжимости брака, христианскому пониманию и значению брачного союза. Рассматривается история вопроса нерасторжимости брака и отношение к нему в разные периоды жизни Церкви. Значительная часть исследования посвящена каноническому обоснованию нерасторжимости брака. Раскрывается Ветхозаветное и Новозаветное учение Церкви о браке. Проведен анализ канонов, а также рассмотрены комментарии авторитетных канонистов, посвященных данной тематике.

This article focuses on the issue of the irreducibility of marriage, the Christian understanding of the marriage union, and its importance and significance. It reviews the history of the issue of the non-dissolution of marriage and the attitude toward it in different periods of the life of the Church. A large part of the work is devoted to the canonical basis of the irreducibility of marriage. The Old Testament and New Testament teaching of the Church on marriage is disclosed. An analysis of the canons is made, and comments by authoritative canonists on the subject are considered.
Primacy and Sobornost: the view of Russian theologians
Authors: Задорнов Александр
Published: April 2024

В статье анализируется содержание двух сборников по проблеме первенства и соборности в Церкви, вышедшие в России в 2022–2023 гг. Прослеживаются общие тенденции в рефлексии на тему соборности как богословского, культурного и исторического понятия, отмечается канонический аспект понятия первенства и межправославных отношений.

The article analyses the content of two collections on the problem of primacy and sobornost in the Church, published in Russia in 2022–2023. The article analyses the content of two collections on the problem of primacy and sobornost in the Church, published in Russia in 2022–2023. The general trends in reflection on the topic of sobornost as a theological, cultural and historical concept are traced, and the canonical aspect of the concept of primacy and inter-Orthodox relations is noted.
Normalized solutions of quasilinear Schrödinger equations with a general nonlinearity
Authors: Deng Ting , Squassina Marco , Zhang Jianjun , Zhong Xuexiu
Published: April 2024

We are concerned with solutions of the following quasilinear Schrödinger equations − div ( φ 2 ( u ) ∇ u ) + φ ( u ) φ ′ ( u ) | ∇ u | 2 + λ u = f ( u ) , x ∈ R N with prescribed mass ∫ R N u 2 d x = c , where N ⩾ 3, c > 0, λ ∈ R appears as the Lagrange multiplier and φ ∈ C 1 ( R , R + ). The nonlinearity f ∈ C ( R , R ) is allowed to be mass-subcritical, mass-critical and mass-supercritical at origin and infinity. Via a dual approach, the fixed point index and a global branch approach, we establish the existence of normalized solutions to the problem above. The results extend previous results by L. Jeanjean, J. J. Zhang and X.X. Zhong to the quasilinear case.
Application of an artificial intelligence for quantitative analysis of endothelial capillary beds in vitro
Authors: Magnusson Marine M. M. , Schüpbach-Regula Gertraud , Rieger Juliane , Plendl Johanna , Marin Ilka , Drews Barbara , Kaessmeyer Sabine
Published: April 2024

BACKGROUND: The use of endothelial cell cultures has become fundamental to study angiogenesis. Recent advances in artificial intelligences (AI) offer opportunities to develop automated assessment methods in medical research, analyzing larger datasets. OBJECTIVE: The aim of this study was to compare the application of AI with a manual method to morphometrically quantify in vitro angiogenesis. METHODS: Co-cultures of human microvascular endothelial cells and fibroblasts were incubated mimicking endothelial capillary-beds. An AI-software was trained for segmentation of endothelial capillaries on anti-CD31-labeled light microscope crops. Number of capillaries and branches and average capillary diameter were measured by the AI and manually on 115 crops. RESULTS: The crops were analyzed faster by the AI than manually (3 minutes vs 1 hour per crop). Using the AI, systematically more capillaries (mean 48/mm2 vs 27/mm2) and branches (mean 23/mm2 vs 11/mm2) were counted than manually. Both methods had a strong linear relationship in counting capillaries and branches (r-capillaries = 0.88, r-branches = 0.89). No correlation was found for measurements of the diameter (r-diameter = 0.15). CONCLUSIONS: The present AI reduces the time required for quantitative analysis of angiogenesis on large datasets, and correlates well with manual analysis.
Management optimization strategy of the closed-loop supply chain by deep learning technology
Authors: Gao Chunjuan
Published: April 2024

With the continuous progress of science and the development of society, there are also problems of resource shortage and environmental pollution. People are eager to change this situation. How to achieve sustainable development has become an important problem to be solved. The development of society is inseparable from the supply chain, but the traditional supply chain cannot meet the requirements of sustainable development. The research manifests that the Closed-Loop supply chain (CLSC) can protect the environment while economic development, and achieve harmonious coexistence between man and nature. CLSC is studied initially, and the connotation and characteristics of CLSC are introduced. A management optimization of CLSC based on deep learning technology is proposed. Meanwhile, the genetic simulated annealing algorithm is used for simulation, and the obtained solution is the optimal solution. And this algorithm has good convergence, which provides new ideas for the future development of Chinese enterprises.
Alzheimer’s Disease in Lebanon: Exploring Genetic and Environmental Risk Factors—A Comprehensive Review
Authors: Khaled Mohamad , Al-Jamal Hadi , Tajer Layla , El-Mir Reem
Published: April 2024

Alzheimer’s disease (AD) is a neurodegenerative condition that displays a high prevalence in Lebanon causing a local burden in healthcare and socio-economic sectors. Unfortunately, the lack of prevalence studies and clinical trials in Lebanon minimizes the improvement of AD patient health status. In this review, we include over 155 articles to cover the different aspects of AD ranging from mechanisms to possible treatment and management tools. We highlight some important modifiable and non-modifiable risk factors of the disease including genetics, age, cardiovascular diseases, smoking, etc. Finally, we propose a hypothetical genetic synergy model between APOE4 and TREM2 genes which constitutes a potential early diagnostic tool that helps in reducing the risk of AD based on preventative measures decades before cognitive decline. The studies on AD in Lebanon and the Middle East are scarce. This review points out the importance of genetic mapping in the understanding of disease pathology which is crucial for the emergence of novel diagnostic tools. Hence, we establish a rigid basis for further research to identify the most influential genetic and environmental risk factors for the purpose of using more specific diagnostic tools and possibly adopting a local management protocol.
Incident Dementia After Spontaneous Intracerebral Hemorrhage
Authors: Zhang Zheting , Lim Mervyn Jun Rui
Published: April 2024

Post-stroke cognitive impairment and dementia (PSCID) is a complication that affects long-term functional outcomes after stroke. Studies on dementia after long-term follow-up in stroke have focused predominantly on ischemic stroke, which may be different from the development of dementia after spontaneous intracerebral hemorrhage (ICH). In this review, we summarize the existing data and hypotheses on the development of dementia after spontaneous ICH, review the management of post-ICH dementia, and suggest areas for future research. Dementia after spontaneous ICH has a cumulative incidence of up to 32.0–37.4% at 5 years post-ICH. Although the pathophysiology of post-ICH dementia has not been fully understood, two main theoretical frameworks can be considered: 1) the triggering role of ICH (both primary and secondary brain injury) in precipitating cognitive decline and dementia; and 2) the contributory role of pre-existing brain pathology (including small vessel disease and neurodegenerative pathology), reduced cognitive reserve, and genetic factors predisposing to cognitive dysfunction. These pathophysiological pathways may have synergistic effects that converge on dysfunction of the neurovascular unit and disruptions in functional connectivity leading to dementia post-ICH. Management of post-ICH dementia may include screening and monitoring, cognitive therapy, and pharmacotherapy. Non-invasive brain stimulation is an emerging therapeutic modality under investigation for safety and efficacy. Our review highlights that there remains a paucity of data and standardized reporting on incident dementia after spontaneous ICH. Further research is imperative for determining the incidence, risk factors, and pathophysiology of post-ICH dementia, in order to identify new therapies for the treatment of this debilitating condition.
Insulin-Degrading Enzyme Efficiently Degrades polyQ Peptides but not Expanded polyQ Huntingtin Fragments
Authors: Geijtenbeek Karlijne W. , Aranda Angela Santiago , Sanz Alicia Sanz , Janzen Jolien , Bury Aleksandra E. , Kors Suzan , Al Amery Nur , Schmitz Nina C.M. , Reits Eric A.J. , Schipper-Krom Sabine
Published: April 2024

Background: Huntington’s disease is an inheritable autosomal dominant disorder caused by an expanded CAG trinucleotide repeat within the Huntingtin gene, leading to a polyglutamine (polyQ) expansion in the mutant protein. Objective: A potential therapeutic approach for delaying or preventing the onset of the disease involves enhancing the degradation of the aggregation-prone polyQ-expanded N-terminal mutant huntingtin (mHTT) exon1 fragment. A few proteases and peptidases have been identified that are able to cleave polyQ fragments with low efficiency. This study aims to identify a potent polyQ-degrading endopeptidase. Methods: Here we used quenched polyQ peptides to identify a polyQ-degrading endopeptidase. Next we investigated its role on HTT turnover, using purified polyQ-expanded HTT fragments and striatal cells expressing mHTT exon1 peptides. Results: We identified insulin-degrading enzyme (IDE) as a novel endopeptidase for degrading polyQ peptides. IDE was, however, ineffective in reducing purified polyQ-expanded HTT fragments. Similarly, in striatal cells expressing mHTT exon1 peptides, IDE did not enhance mHTT turnover. Conclusions: This study shows that despite IDE’s efficiency in degrading polyQ peptides, it does not contribute to the direct degradation of polyQ-expanded mHTT fragments.
RETRACTED: Enhancing quality-driven iot operations for smart cities: A comprehensive approach for routing, security, and optimization
Authors: Tino Merlin R. , Ravi R.
Published: April 2024

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Psychometrics of inertial heading perception
Authors: Geno Olivia , Critelli Kyle , Arduino Cesar , Crane Benjamin T. , Anson Eric R.
Published: April 2024

BACKGROUND: Inertial self-motion perception is thought to depend primarily on otolith cues. Recent evidence demonstrated that vestibular perceptual thresholds (including inertial heading) are adaptable, suggesting novel clinical approaches for treating perceptual impairments resulting from vestibular disease. OBJECTIVE: Little is known about the psychometric properties of perceptual estimates of inertial heading like test-retest reliability. Here we investigate the psychometric properties of a passive inertial heading perceptual test. METHODS: Forty-seven healthy subjects participated across two visits, performing in an inertial heading discrimination task. The point of subjective equality (PSE) and thresholds for heading discrimination were identified for the same day and across day tests. Paired t-tests determined if the PSE or thresholds significantly changed and a mixed interclass correlation coefficient (ICC) model examined test-retest reliability. Minimum detectable change (MDC) was calculated for PSE and threshold for heading discrimination. RESULTS: Within a testing session, the heading discrimination PSE score test-retest reliability was good (ICC = 0. 80) and did not change (t(1,36) = –1.23, p = 0.23). Heading discrimination thresholds were moderately reliable (ICC = 0.67) and also stable (t(1,36) = 0.10, p = 0.92). Across testing sessions, heading direction PSE scores were moderately correlated (ICC = 0.59) and stable (t(1,46) = –0.44, p = 0.66). Heading direction thresholds had poor reliability (ICC = 0.03) and were significantly smaller at the second visit (t(1,46) = 2.8, p = 0.008). MDC for heading direction PSE ranged from 6–9 degrees across tests. CONCLUSION: The current results indicate moderate reliability for heading perception PSE and provide clinical context for interpreting change in inertial vestibular self-motion perception over time or after an intervention.
Yogistic efficacy on cardiopulmonary capacities, endurance efficiencies and musculoskeletal potentialities in female college students
Authors: Mitra Sudeep , Mitra Mousumi , Nandi Purna , Saha Mantu , Nandi Dilip Kumar
Published: April 2024

BACKGROUND: Physical exercise participation among female students is significantly compromised throughout the academic periods of college or university due to scholastic demands and also by less parental and community encouragements. Thus, physical inactivity in female college students leads to less musculoskeletal efficiency and work performance. OBJECTIVE: Customized yogic module may be considered to enhance both aerobic and anaerobic power, pulmonary capacity and musculoskeletal efficiency for the improvement of systemic body functions among female college students. METHODS: A randomized, controlled parallel study design (n = 60; age = 20.16±2.05 years), on sedentary female college students practicing customized yogic module (n = 30) for 5 days / week for 3 months (60 min daily in the morning) to observe anthropometric, physiological, cardiopulmonary and muscular endurance indices. RESULTS: After yogic practice, a significant reduction in body fat (p < 0.05) (%), heart rate (p < 0.001), systolic blood pressure (p < 0.001), double product (p‹0.01) and rate pressure product (p < 0.05) were estimated. Significant improvement (p < 0.001) in vital capacity, forced expiratory volume in 1 sec was also observed. Evaluation of hand grip strength, maximal oxygen consumption and physical work capacity showed significant increase (p < 0.01) after yogic intervention. CONCLUSIONS: A three-month customized yogic training improved resting physiological activities, cardiopulmonary functions, musculoskeletal strength and endurance fitness due to focused breathing, mindfulness meditation and by stretching-strengthening patterns for achieving recreational physical activity among female college students.
Application of Eastern Philosophical Principles to Ethical Dilemmas in Daily Medical Practice
Authors: Garg Arsh , Dahia Simranjeet Singh
Published: April 2024

This mini review highlights the underappreciated influence of Indian philosophical principles on medical ethics. Emphasizing concepts such as ahimsa, dharma, compassion, impermanence, non-attachment, and holistic healing, it explores their profound relevance in guiding healthcare professionals through complex ethical dilemmas. While Western philosophies dominate medical ethics discourse, there is a need to acknowledge and research the application of non-Western philosophies in medical practice. A broader recognition and integration of non-Western ethical principles to medical practice can foster culturally sensitive and ethically sound patient care.
Radical Development of Engineering Institutions in The Industrial Corridors
Authors: Vedhathiri Thanikachalam , V. Thamil Arasu , T. Sivanesan , B.V. Mathew , S. Subbaraj , E. Srividhya , Rani Sheeba
Published: April 2024

In the last fifteen years, lakhs of engineering students have not gotten any employment and more than 1000 engineering colleges were closed. The reasons are insufficient qualified faculty members, nonaccredited programs, no exposure to industries, poor infrastructure, and colleges not having linkages with the industries. The global review indicates that almost all engineering institutions are offering various industry-relevant courses and the students are undergoing adequate industrial training, have sufficient attributes, and are industry-ready. This enables the graduates to get industrial placement. The objectives of this research are to review the global practices in offering industry-specific curricula, on-the-job training, a framework to improve the linkages with the industries, the art of nurturing industrial collaboration, and a policy framework for radical developing industry-ready graduates. An action research method has been utilized in this project. It is concluded to actively create a link with the companies in the nation, develop industry-relevant and/or industry-specific and flexible curricula, and offer it with active collaboration with industries in the corridor. Ten suggestions are recommended to improve the abilities and skills of the engineering graduates and the faculty members. It is suggested to nurture various stakeholders and bring a win-win solution. Further, this focuses on creating a policy framework and cooperation of professional associations. All these focused on radical innovation in outcome-based curricula with active collaboration with employers.
Exploration of Quartz, Feldspar, and Mica Minerals Using Geophysical Resistivity, Self-Potential, and Natural Electrical Field Techniques
Authors: Golla Veeraswamy
Published: April 2024

The aim of the present study is examined by various modeling and self-potential (SP) techniques which are useful for the exploitation of shallow and deep deposits. In the present study area, 12 areas conducted the self-potential techniques. From that analysis, a v-shaped formation was formed, as may be the geological formation of an ore anomaly. The study area's highest millivolt values (30 to 50 mV) indicate the presence of quartz, feldspar, and negative values are associated with the mica group of minerals. The Nellore schist belt is majorly dominated by the schistose group of rocks. The schistose group of rocks has a density very less like 5 to 10 MV. This study would be helpful for various arenas, including exploration geologists and mineralogists.