bluuebunny/crossref_metadata_2025 huggingface dataset:
Draft Genome Sequence of a Novel
Chitinophaga
sp. Strain, MD30, Isolated from a Biofilm in an Air Conditioner Condensate Pipe
Authors: Wan Xuehua , Darris Maxwell , Hou Shaobin , Donachie Stuart P.
Published: October 2017

Most of the 24 known
Chitinophaga
species were originally isolated from soils. We report the draft genome sequence of a putatively novel
Chitinophaga
sp. from a biofilm in an air conditioner condensate pipe. The genome comprises 7,661,303 bp in one scaffold, 5,694 predicted protein-coding sequences, and a G+C content of 47.6%.
Draft Genome Sequence of a Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300 Isolate from a River Sample
Authors: Lepuschitz Sarah , Mach Robert , Springer Burkhard , Allerberger Franz , Ruppitsch Werner
Published: October 2017

The increasing emergence of multiresistant bacteria in health care settings in the community and in the environment represents a major health threat worldwide. Here, we report the draft genome sequence of a community-acquired methicillin-resistant
Staphylococcus aureus
(CA-MRSA) USA300 isolate (W1) from a small river in southern Austria.
Antimicrobial Resistance in
Rhodococcus equi
Authors: Giguère Steeve , Berghaus Londa J. , Willingham-Lane Jennifer M.
Published: October 2017

Pneumonia caused by
Rhodococcus equi
remains an important cause of disease and death in foals. The combination of a macrolide (erythromycin, azithromycin, or clarithromycin) with rifampin has been the recommended treatment for foals with clinical signs of infection caused by
R. equi
since the early 1980s with, until recently, only rare reports of resistance. Resistance to macrolides and rifampin in isolates of
R. equi
cultured from horses is increasing, with isolates resistant to all macrolides and rifampin now being cultured from up to 40% of infected foals at some farms. This text reviews the available data regarding antimicrobial resistance in
R. equi
, with emphasis on the molecular mechanisms of the recent emergence of resistance to macrolides and rifampin in equine isolates of
R. equi
.
Result of Health Illiteracy and Cultural Stigma: Fournier’s Gangrene, a Urological Emergency
Authors: Jiwrajka Manasi , Pratap Krishan , Yaxley William , Dunglison Nigel
Published: October 2017

A 63-year-old Caucasian man presents to his regional hospital 8 days postinsertion of beads in his urethra, causing Fournier’s gangrene of the penis and delayed surgical management of his gangrene. The reasons for his delay are cultural stigma associated with sexual practices and health illiteracy.
Expression and prognostic significance of ECT2 in invasive breast cancer
Authors: Wang Hong-kun , Liang Jian-fang , Zheng Hui-xia , Xiao Hong
Published: October 2017

Aims

To investigate the expression of epithelial cell transforming sequence 2 (ECT2) in invasive breast cancer and its prognostic significance.

Methods

ECT2 immunohistochemical detection was performed in 165 breast cancer specimens and 100 normal control tissues. Univariable and multivariable Cox proportional hazards regression model analysis was used to confirm independent prognostic factors. The PHREG procedure linear hypotheses testing method was used to analyse survival data.

Results

Expression of ECT2 in breast cancer was significantly higher than that of the normal control group (p<0.001), and it was related to tumour grade, the status of lymph node metastasis, TNM staging, recurrence status, menopausal status, and the Ki-67 proliferation index (p<0.05), and not related to age, tumour size, tumour type, expression of estrogen receptor, progesterone receptor and human epidermal growth factor 2, and triple-negative disease (p>0.05). Univariable analysis showed that expression of ECT2, the status of lymph node metastasis, triple-negative disease and Ki-67 proliferation index were related to the overall survival of patients with breast cancer (p<0.001, p=0.006, p=0.001, p=0.041, respectively). PHREG procedure linear hypotheses testing results for overall survival revealed that high expression of ECT2, lymph node metastasis, triple-negative disease and high Ki-67 proliferation index predicted lower overall survival rates. Multivariable Cox regression indicated that high expression of ECT2 and triple-negative disease were independent prognostic factors for patients with breast cancer (p<0.001, p=0.004, respectively).

Conclusions

Expression of ECT2 may be one of the main causes of the occurrence and development of breast cancer, and high expression of ECT2 as an independent prognostic factor predicts a poor prognosis. ECT2 could also be a potential molecular target for designing therapeutic strategies for breast cancer.
Myelographic and low‐field magnetic resonance imaging findings in dogs with presumptive acute hydrated non‐compressive nucleus pulposus extrusion
Authors: Ros Carlos , de la Fuente Cristian , Rodenas Sergio , Novellas Rosa , Viu Judit , AÃ±or Sonia
Published: October 2017

MRI is considered gold standard for the diagnosis of presumptive acute hydrated non‐compressive nucleus pulposus extrusions (AHNCNPE). This retrospective study describes the myelographic findings in dogs with AHNCNPE diagnosed by low‐field MRI and their association with neurological grade, need of surgical decompression and outcome. Forty‐two myelographies (21 dogs with presumptive AHNCNPE, 21 dogs with Hansen type I disc disease herniation) were blindly evaluated. Site of herniation, compression pattern, ratio of length of the lesion to length of the second lumbar vertebra (LL:L2) and degree of spinal cord compression (SCC) were measured on the myelographies of dogs with presumptive AHNCNPE and were compared with the corresponding MRI features. Percentage of extruded volume of nucleus pulposus (VNP) was calculated on MR images. Myelographic interobserver agreement for presumptive diagnosis of AHNCNPE was almost perfect (Îº=0.8). Accuracy of myelography to detect site of herniation was 80.9 per cent and to identify extradural compression was 57.1 per cent. Mean SCC was 5.8Â±2.6 per cent for myelography and 6.6Â±3 per cent for MRI. Mean LL:L2 ratio was 1.7Â±0.9 for myelography and 1.2Â±0.8 for MRI. Mean percentage of extruded VNP was 40Â±14 per cent, and it was positively associated with neurological grade.
Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales
Authors: Grierson Sylvia S , Werling Dirk , Bidewell Cornelia , Williamson Susanna
Published: October 2017

Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed. The authors carried out a genotyping study to characterise PCV2 associated with confirmed PCVD cases in England and Wales from 2011 to January 2016 (n=65). A partial fragment of PCV2 genome encompassing ORF2 was amplified and sequenced from 45 cases of PCVD. The majority of sequences were genotype PCV2b but four sequences were PCV2d. The significance of the emergence of PCV2d in England and elsewhere in the world is not yet known, although it does appear to represent an ongoing global genotype shift.
A real-time control method-based simulation for high-speed trains on large-scale rail network
Authors: Liu Yutong , Cao Chengxuan , Zhou Yaling , Feng Ziyan
Published: October 2017

In this paper, an improved real-time control model based on the discrete-time method is constructed to control and simulate the movement of high-speed trains on large-scale rail network. The constraints of acceleration and deceleration are introduced in this model, and a more reasonable definition of the minimal headway is also presented. Considering the complicated rail traffic environment in practice, we propose a set of sound operational strategies to excellently control traffic flow on rail network under various conditions. Several simulation experiments with different parameter combinations are conducted to verify the effectiveness of the control simulation method. The experimental results are similar to realistic environment and some characteristics of rail traffic flow are also investigated, especially the impact of stochastic disturbances and the minimal headway on the rail traffic flow on large-scale rail network, which can better assist dispatchers in analysis and decision-making. Meanwhile, experimental results also demonstrate that the proposed control simulation method can be in real-time control of traffic flow for high-speed trains not only on the simple rail line, but also on the complicated large-scale network such as China’s high-speed rail network and serve as a tool of simulating the traffic flow on large-scale rail network to study the characteristics of rail traffic flow.
First-order discrete Faddeev gravity at strongly varying fields
Authors: Khatsymovsky V. M.
Published: October 2017

We consider the Faddeev formulation of general relativity (GR), which can be characterized by a kind of d-dimensional tetrad (typically d = 10) and a non-Riemannian connection. This theory is invariant w.r.t. the global, but not local, rotations in the d-dimensional space. There can be configurations with a smooth or flat metric, but with the tetrad that changes abruptly at small distances, a kind of “antiferromagnetic” structure.

Previously, we discussed a first-order representation for the Faddeev gravity, which uses the orthogonal connection in the d-dimensional space as an independent variable. Using the discrete form of this formulation, we considered the spectrum of (elementary) area. This spectrum turns out to be physically reasonable just on a classical background with large connection like rotations by [Formula: see text], that is, with such an “antiferromagnetic” structure.

In the discrete first-order Faddeev gravity, we consider such a structure with periodic cells and large connection and strongly changing tetrad field inside the cell. We show that this system in the continuum limit reduces to a generalization of the Faddeev system. The action is a sum of related actions of the Faddeev type and is still reduced to the GR action.
Black hole event horizons — Teleology and predictivity
Authors: Bhattacharya Swastik , Shankaranarayanan S.
Published: October 2017

General Relativity predicts the existence of black holes. Access to the complete spacetime manifold is required to describe the black hole. This feature necessitates that black hole dynamics is specified by future or teleological boundary condition. Here, we demonstrate that the statistical mechanical description of black holes, the raison d’être behind the existence of black hole thermodynamics, requires teleological boundary condition. Within the fluid–gravity paradigm — Einstein’s equations when projected on spacetime horizons resemble Navier–Stokes equation of a fluid — we show that the specific heat and the coefficient of bulk viscosity of the horizon fluid are negative only if the teleological boundary condition is taken into account. We argue that in a quantum theory of gravity, the future boundary condition plays a crucial role. We briefly discuss the possible implications of this at late stages of black hole evaporation.
Band structures of one-dimensional buckled Arsenene nanoribbons: Strain and quantum size modulations
Authors: Luo Yanwei , Li Yuxiao , Guo Peng , Chen Weiguang , Tang Yanan , Jia Yu
Published: October 2017

In this work, we use first-principles methods to study the strain effects on the band structures of the armchair and zigzag arsenene nanoribbons (A-AsNRs and Z-AsNRs), as well as considering different ribbon widths. The results show that the band gap for each considered arsenene nanoribbons can be decreased when the size is increased. Moreover, strain can also reduce effectively the band gap of AsNRs. Interestingly, for A-AsNRs case, the indirect to direct band transition can be obtained under the tensile strain. In comparision, the direct–indirect transition only occurs under some strain ranges for zigzag AsNRs (Z-AsNRs).
The fully nonconforming virtual element method for biharmonic problems
Authors: Antonietti P. F. , Manzini G. , Verani M.
Published: October 2017

In this paper, we address the numerical approximation of linear fourth-order elliptic problems on polygonal meshes. In particular, we present a novel nonconforming virtual element discretization of arbitrary order of accuracy for biharmonic problems. The approximation space is made of possibly discontinuous functions, thus giving rise to the fully nonconforming virtual element method. We derive optimal error estimates in a suitable (broken) energy norm and present numerical results to assess the validity of the theoretical estimates.
Maximal proper force, black hole horizons and matter as curvature in momentum space
Authors: Castro Carlos
Published: October 2017

Starting with the study of the geometry on the cotangent bundle (phase space), it is shown that the maximal proper force condition, in the case of a uniformly accelerated observer of mass [Formula: see text] along the [Formula: see text] axis, leads to a minimum value of [Formula: see text] lying [Formula: see text] the Rindler wedge and given by the black hole horizon radius [Formula: see text]. Whereas in the uniform circular motion case, we find that the maximal proper force condition implies that the radius of the circle cannot exceed the value of the horizon radius [Formula: see text]. A correspondence is found between the black hole horizon radius and a singularity in the curvature of momentum space. The fact that the geometry (metric) in phase spaces is observer-dependent (on the momentum of the massive particle/observer) indicates further that the matter stress energy tensor and vacuum energy in the underlying space-time may admit an interpretation in terms of the curvature in momentum spaces. Some final comments are made pertaining to the Asymptotic Safety program in gravity and why phase space geometry seems to be a proper arena for a space–time–matter unification.
Towards modeling pedestrian’s invisible trail for simulating crowd movement
Authors: Wang Hao , Xiong Muzhou
Published: October 2017

Crowd modeling and simulation have drawn much attention in recent decades due to the functionality of recurrence of the crowd movement pattern in an efficient way. Much effort has been paid aiming at generating an accurate simulation result with respect to different aspects of crowd movement pattern. A fact has been observed that footprint left in mud or turf significantly affects pedestrian’s decision making and moving trajectory since those footprints help other pedestrians walk comfortably. Inspired by this, we in this paper propose a crowd simulation model aiming to model how the movement of previous pedestrians affects decision making process of the pedestrians coming later. Unlike pedestrians leaving footprint in mud or turf, pedestrians leave no marks on hard surface. We consider each step of pedestrian moving on hard surface as a mutable invisible footprint which further forms a virtual trail. We first build a model to simulate how the invisible footprint forms and evolves on hard surface, upon which an agent-based crowd simulation model is then built to simulate how pedestrian makes trade-off between the invisible trajectory and the shortest path. The proposed model is validated by case studies with two scenarios. The simulation results indicate that we are able to simulate the impact on pedestrian’s decision making by the invisible footprint.
THE DYNAMICS OF GOVERNMENT BOND YIELDS IN THE EURO ZONE
Authors: AKRAM TANWEER , DAS ANUPAM
Published: October 2017

This paper investigates the determinants of nominal yields of government bonds in the euro zone. The pooled mean group (PMG) technique of cointegration is applied on both monthly and quarterly datasets to examine the major drivers of nominal yields of long-term government bonds in a set of 11 euro zone countries. Furthermore, the autoregressive distributive lag (ARDL) methods are used to address the same question for individual countries. The results show that short-term interest rates are the most important determinants of long-term government bonds’ nominal yields. These results support Keynes’s view that short-term interest rates and other monetary policy measures have a decisive influence on long-term interest rates on government bonds.
Coronary capillary blood flow in a rat model of congestive heart failure
Authors: Kagan Heather J. , Belekdanian Varujan D. , Chen Jiqiu , Backeris Peter , Hammoudi Nadjib , Turnbull Irene C. , Costa Kevin D. , Hajjar Roger J.
Published: October 2017

The aim of this study was to explore the role of abnormal coronary microvasculature morphology and hemodynamics in the development of congestive heart failure (CHF). CHF was induced in rats by aortic banding, followed by ischemia-reperfusion and later aortic debanding. Polymerized casts of coronary vasculature were imaged under a scanning electron microscope (SEM). Matrix Laboratory (MATLAB) software was used to calculate capillary structure index (CSI), a measure of structural alignment also called mean vector length (MVL), for 93 SEM images of coronary capillaries (CSI→1 perfect linearity; CSI→0 circular disarray). CSI was incorporated as a constant to represent tortuosity and nonlaminar flow in Poiseuille’s equation to estimate the differences in capillary blood flow rate, velocity, and resistance for CHF vs. control. The morphology of CHF capillaries is significantly disordered and tortuous compared with control (CSI: 0.35 ± 0.02 for 61 images from 7 CHF rats; 0.58 ± 0.02 for 32 images from 7 control rats; P < 0.01). Estimated capillary resistance in CHF is elevated by 173% relative to control, while blood flow rate and blood velocity are 56 and 43% slower than control. Capillary resistance increased 67% due to the significantly narrower capillary diameter in CHF, while it increased an additional 105% due to tortuosity. The significant structural abnormalities of CHF coronary capillaries may drastically stagnate hemodynamics in myocardium and increase resistance to blood flow. This could play a role in the development of CHF.

NEW & NOTEWORTHY In the present study, coronary capillary tortuosity was measured by applying Matrix Laboratory software to scanning electron microscope images of capillaries in a rat model of congestive heart failure. Stagnant blood flow in coronary capillaries may play a role in the development of congestive heart failure. The application of computer modeling to histological and physiological data to characterize the hemodynamics of coronary microcirculation is a new area of study.
Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM
Authors: Song Kyung-A , Niederst Matthew J. , Lochmann Timothy L. , Hata Aaron N. , Kitai Hidenori , Ham Jungoh , Floros Konstantinos V. , Hicks Mark A. , Hu Haichuan , Mulvey Hillary E. , Drier Yotam , Heisey Daniel A.R. , Hughes Mark T. , Patel Neha U. , Lockerman Elizabeth L. , Garcia Angel , Gillepsie Shawn , Archibald Hannah L. , Gomez-Caraballo Maria , Nulton Tara J. , Windle Brad E. , Piotrowska Zofia , Sahingur Sinem E. , Taylor Shirley M. , Dozmorov Mikhail , Sequist Lecia V. , Bernstein Bradley , Ebi Hiromichi , Engelman Jeffrey A. , Faber Anthony C.
Published: October 2017

Purpose: Epithelial-to-mesenchymal transition (EMT) confers resistance to a number of targeted therapies and chemotherapies. However, it has been unclear why EMT promotes resistance, thereby impairing progress to overcome it.

Experimental Design: We have developed several models of EMT-mediated resistance to EGFR inhibitors (EGFRi) in EGFR-mutant lung cancers to evaluate a novel mechanism of EMT-mediated resistance.

Results: We observed that mesenchymal EGFR-mutant lung cancers are resistant to EGFRi-induced apoptosis via insufficient expression of BIM, preventing cell death despite potent suppression of oncogenic signaling following EGFRi treatment. Mechanistically, we observed that the EMT transcription factor ZEB1 inhibits BIM expression by binding directly to the BIM promoter and repressing transcription. Derepression of BIM expression by depletion of ZEB1 or treatment with the BH3 mimetic ABT-263 to enhance “free” cellular BIM levels both led to resensitization of mesenchymal EGFR-mutant cancers to EGFRi. This relationship between EMT and loss of BIM is not restricted to EGFR-mutant lung cancers, as it was also observed in KRAS-mutant lung cancers and large datasets, including different cancer subtypes.

Conclusions: Altogether, these data reveal a novel mechanistic link between EMT and resistance to lung cancer targeted therapies. Clin Cancer Res; 24(1); 197–208. ©2017 AACR.
Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells
Authors: Olson Brian M. , Gamat Melissa , Seliski Joseph , Sawicki Thomas , Jeffery Justin , Ellis Leigh , Drake Charles G. , Weichert Jamey , McNeel Douglas G.
Published: October 2017

Androgen deprivation is the primary therapy for recurrent prostate cancer, and agents targeting the androgen receptor (AR) pathway continue to be developed. Because androgen-deprivation therapy (ADT) has immmunostimulatory effects as well as direct antitumor effects, AR-targeted therapies have been combined with other anticancer therapies, including immunotherapies. Here, we sought to study whether an antigen-specific mechanism of resistance to ADT (overexpression of the AR) may result in enhanced AR-specific T-cell immune recognition, and whether this might be strategically combined with an antitumor vaccine targeting the AR. Androgen deprivation increased AR expression in human and murine prostate tumor cells in vitro and in vivo. The increased expression persisted over time. Increased AR expression was associated with recognition and cytolytic activity by AR-specific T cells. Furthermore, ADT combined with vaccination, specifically a DNA vaccine encoding the ligand-binding domain of the AR, led to improved antitumor responses as measured by tumor volumes and delays in the emergence of castrate-resistant prostate tumors in two murine prostate cancer models (Myc-CaP and prostate-specific PTEN-deficient mice). Together, these data suggest that ADT combined with AR-directed immunotherapy targets a major mechanism of resistance, overexpression of the AR. This combination may be more effective than ADT combined with other immunotherapeutic approaches. Cancer Immunol Res; 5(12); 1074–85. ©2017 AACR.
Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition
Authors: Stuhlmiller Timothy J. , Zawistowski Jon S. , Chen Xin , Sciaky Noah , Angus Steven P. , Hicks Sean T. , Parry Traci L. , Huang Wei , Beak Ju Youn , Willis Monte S. , Johnson Gary L. , Jensen Brian C.
Published: October 2017

Background

Most novel cancer therapeutics target kinases that are essential to tumor survival. Some of these kinase inhibitors are associated with cardiotoxicity, whereas others appear to be cardiosafe. The basis for this distinction is unclear, as are the molecular effects of kinase inhibitors in the heart.

Methods and Results

We administered clinically relevant doses of sorafenib, sunitinib (cardiotoxic multitargeted kinase inhibitors), or erlotinib (a cardiosafe epidermal growth factor receptor inhibitor) to mice daily for 2 weeks. We then compared the effects of these 3 kinase inhibitors on the cardiac transcriptome using
RNA
seq and the cardiac kinome using multiplexed inhibitor beads coupled with mass spectrometry. We found unexpectedly broad molecular effects of all 3 kinase inhibitors, suggesting that target kinase selectivity does not define either the molecular response or the potential for cardiotoxicity. Using in vivo drug administration and primary cardiomyocyte culture, we also show that the cardiosafety of erlotinib treatment may result from upregulation of the cardioprotective signal transducer and activator of transcription 3 pathway, as co‐treatment with erlotinib and a signal transducer and activator of transcription inhibitor decreases cardiac contractile function and cardiomyocyte fatty acid oxidation.

Conclusions

Collectively our findings indicate that preclinical kinome and transcriptome profiling may predict the cardiotoxicity of novel kinase inhibitors, and suggest caution for the proposed therapeutic strategy of combined signal transducer and activator of transcription/epidermal growth factor receptor inhibition for cancer treatment.
Prolyl 4‐Hydroxylase Domain Protein 3 Overexpression Improved Obstructive Sleep Apnea—Induced Cardiac Perivascular Fibrosis Partially by Suppressing Endothelial‐to‐Mesenchymal Transition
Authors: Zhang Guang‐hao , Yu Fu‐chao , Li Yang , Wei Qin , Song Song‐song , Zhou Fang‐ping , Tong Jia‐yi
Published: October 2017

Background

Intermittent hypoxia (IH) induced by obstructive sleep apnea is the key factor involved in cardiovascular fibrosis. Under persistent hypoxia condition, endothelial cells respond by endothelial‐to‐mesenchymal transition (EndMT), which is associated with cardiovascular fibrosis. Prolyl 4‐hydroxylase domain protein 3 (PHD3) is a cellular oxygen sensor and its expression increased in hypoxia. However, its role in obstructive sleep apnea–induced EndMT and cardiovascular fibrosis is still uncertain. We investigated the potential mechanism of obstructive sleep apnea–induced cardiac perivascular fibrosis and the role of PHD3 in it.

Methods and Results

In vivo, C56BL/6 mice were exposed to IH for 12 weeks. PHD3 expression was changed by lentivirus‐mediated short‐hairpin PHD3 and lentivirus carrying PHD3 cDNA. EndMT related protein levels, histological and functional parameters were detected after 12 weeks. In vitro, human umbilical vein endothelial cells were treated with IH/short‐hairpin PHD3/lentivirus carrying PHD3 cDNA to explore the mechanism of PHD3 in altered function of human umbilical vein endothelial cells. We found that chronic intermittent hypoxia increase PHD3 expression and EndMT. In vivo, IH accelerate cardiac dysfunction and aggravate collagen deposition via the process of EndMT. And, when PHD3 were overexpressed, cardiac dysfunction and collagen excessive deposition were improved. In vitro, IH induced EndMT, which endow human umbilical vein endothelial cells spindle morphology and an enhanced ability to migration and collagen secretion. PHD3 overexpression in cultured human umbilical vein endothelial cells ameliorated IH–induced EndMT through inactivating hypoxia‐inducible factor 1 alpha and small mothers against decapentaplegic 2 and 3.

Conclusions

Obstructive sleep apnea–induced cardiac perivascular fibrosis is associated with EndMT, and PHD3 overexpression might be beneficial in the prevention of it by inhibiting EndMT. PHD3 overexpression might have therapeutic potential in the treatment of the disease.
Contrasting Contrastive Left-Dislocation Explications
Authors: den Dikken Marcel , Surányi Balázs
Published: October 2017

Of the three logically possible approaches to contrastive left-dislocation (CLD) (base-generation cum deep anaphora; movement cum surface anaphora; elliptical clausal juxtaposition cum resumption), two are represented prominently in the recent literature. Ott’s (2014) account treats CLD uniformly in terms of clausal juxtaposition, the first clause being stripped down to its contrastive topic via an ellipsis operation said to be akin to sluicing. He argues that this analysis is superior to Grohmann’s (2003) approach, featuring movement within a single prolific domain and late spell-out of a resumptive element. Using data mainly from Hungarian and Dutch, we reveal problems for Ott’s biclausal account that undermine its apparent conceptual appeal and compromise its descriptive accuracy. We show that the ellipsis operation required is sui generis, that the approach fails to assimilate the crosslinguistic variation attested in the availability of multiple CLD to known cases of parametric variation in the left periphery, and that it undergenerates in several empirical domains, including P-stranding and “floated” arguments. Grohmann’s movement-cum-surface-anaphora analysis as it stands also cannot handle all these data, but it can be fixed to fit the facts. For Ott’s analysis, no patches seem available. Some further empirical properties of CLD appear underivable from either of these approaches. For these, the base-generation-cum-deep-anaphora analysis can be considered.
Culture of native species of zooplanktonic crustaceans: Tumeodiaptomus diabolicus (Brehm, 1935) from northern Patagonian lakes (Chile)
Authors: Encina-Montoya Francisco , De los Ríos Escalante Patricio , Salazar Katherine
Published: October 2017

The inland waters of Chile hold endemic species of crustaceans, and these habitats are threatened at present due to pollution as a result of human activities. Until now, the environmental studies performed have not considered native species for evaluating environmental risks. The aim of the present study was to do a first culture experiment with the freshwater copepod Tumeodiaoptomus diabolicus that inhabits central and northern Chilean Patagonian lakes. The copepods were cultured under two dietary regimes, i.e., a diet of microalgae and an artificial diet. The experiment was conducted over 12 days, and the maximum growth was obtained with the artificial diet. The present results would agree with similar results obtained for pseudodiaptomid copepods, that are massively used for aquaculture activities. In accordance with the obtained results and published data in the literature, T. diabolicus culture could be relatively easily done, and would thus qualify as an assay for investigating environmental conditions.
Self-determination and Self-governance for Communities Relocated across International Borders: The Quest for Banaban Independence
Authors: McAdam Jane
Published: October 2017

In 1945, the small Banaban community of Ocean Island (Banaba) in present-day Kiribati was relocated to Rabi Island in Fiji. The Balabans were ostensibly moved due to irreversible damage done to Ocean Island during Japanese occupation in the Second World War. However, this was largely a convenient excuse to facilitate the wholesale phosphate mining of the island by the British Phosphate Commission, a consortium of the British, Australian and New Zealand governments. The Banaban relocation provides a rare example of a whole community seeking to re-establish itself in another State. This article charts the Banabans’ bids for independence during the 1960–70s, revealing novel responses to complex questions of self-determination and governance, including legal status, nationality, political representation, and rights to land and resources. While their experience cannot be universalised, it is relevant to contemporary deliberations about the possible future relocation of Pacific communities impacted by climate change.
Models for Jewish Bible Theologies
Authors: Kalimi Isaac
Published: October 2017

Against continuing attempts to define “Old Testament theology” or “biblical theology” in exclusively Christian terms, and in light of ongoing methodological diversity and confusion between proponents of Jewish biblical theology, this article suggests three models for the latter. The first one investigates the theologies of the different parts of the Hebrew Bible on their own, diachronically, without interference from later theology or practice. The second one focuses synchronically on the form of the Hebrew Bible as canonized, and is as objective as this basic biblical text allows. The third one is explicitly subjective and confessional, reading the Hebrew Bible in relation to the larger canon of Judaism, that is, the Oral Torah (= talmudic and midrashic literature). All three models have a legitimate place in the construction of a genuinely Jewish biblical theology, but they must not be confused. They all begin with different presuppositions and pursue different goals, but when properly distinguished, they can also complement one another, each exploring different aspects of the theology of the Jewish Bible.
Christological Monotheism
Authors: Gaston Thomas , Perry Andrew
Published: October 2017

Richard Bauckham and N. T. Wright have proposed that in 1 Corinthians 8:6 Paul consciously expands upon the Shema, and would be understood to be doing so by his intended readers, and thus Paul includes Jesus within the unique divine identity. In this paper we question this proposal on several grounds. We argue that it is unlikely that 1 Corinthians 8:6 would be read as an expansion of the Shema. We demonstrate that κύριος in this context is unlikely to stand for Yhwh. We also raise doubts over the concept of “inclusion” within the divine identity. We conclude that 1 Corinthians 8:6 is better understood as an expression of monotheism simpliciter.
Amanita cingulata, a new annulate species of Amanita sect. Vaginatae from subtropical China
Authors: LIU JIAN-WEI , CAI QING , CUI YANG-YANG , YANG ZHU L.
Published: October 2017

Amanita cingulata, a new species of Amanita sect. Vaginatae with an annulus on the stipe is described based on morphological and molecular evidence. This species was found in forests dominated by members of Fagaceae and/or Pinaceae and is characterized by its small basidioma with a white pileus covered with white and lumpy volval remnants, a pileal margin with short striations, a white fragile annulus, a weak and easily broken lumpy volva on the stipe base and ellipsoid to elongate basidiospores measuring 9–11.5 × 5.5–7 μm. The new species is compared with similar species, especially the annulate taxa of A. sect. Vaginatae.
Neotypification of Terminalia paniculata (Combretaceae)
Authors: CHAKRABARTY TAPAS , KUMAR VENKATACHALAM SAMPATH
Published: October 2017

While preparing a revised treatment of the family Combretaceae for “Flora of India Project,” our attention was drawn on Terminalia paniculata Roth (1821: 383) which was described on the basis of a specimen collected by Benjamin Heyne from peninsular India. The species is well documented in Indian Floras (e.g. Wight & Arnott 1834, Beddome 1869, Brandis 1874, Clarke 1878, Cooke 1903, Talbot 1911, Gamble 1919 and Chandrabose 1983). Gangopadhyay & Chakrabarty (1997) in their revision of the family Combretaceae of Indian subcontinent mentioned that the type of this species is not extant. The type material of T. paniculata housed in the Berlin herbarium (B; herbaria acronyms follow Thiers 2017) was presumably destroyed during the World War II. In the Kew herbarium (K), there is a collection by Benjamin Heyne (K000786096: image!) identified and listed in Wallich’s Numerical List as T. triopteris B.Heyne ex Wallich (1831: no. 3980B). This material contains two twigs, one flowering and the other fruiting and this appears to be a specimen not seen by Roth (1821) since he clearly mentioned in the protologue: “Fructum non vidi.” Thus, as per the provisions of the Code (Mc Neill et al., 2012), as there is no other extant original material (Article 9.7) traceable, a neotype (Articles 9.11 and 9.13) is designated here for T. paniculata from Peninsular India, where Benjamin Heyne made botanical explorations (Burkill, 1965). The neotype specimen is housed in the Central National Herbarium, Botanical Survey of India, Howrah, India (CAL) and its duplicate in the Madras Herbarium, Botanical Survey of India, Southern Regional Centre, Coimbatore, India (MH).
Scoliorhapis stepanovi—new species of sea cucumber from the North-West Pacific (Holothuroidea: Synaptida: Chiridotidae: Taeniogyrinae) and some remarks on the genus Scoliorhapis
Authors: SMIRNOV ALEXEY V. , PANINA ELENA G. , SANAMYAN NADEZHDA P. , SANAMYAN KAREN E.
Published: October 2017

New species Scoliorhapis stepanovi has been collected from depths of 10–23 m on the sandy bottom of Avacha Bay (east coast of Kamchatka), Paramushir Island (North Kuril Islands), and Matua Island (Middle Kuril Islands). It is unique in having sigmoid ossicles in the body wall with points at both ends (without an open-eye, and with the two points lying in a perpendicular plane). Such sigmoids do not occur in any other taeniogyrinid species. The two-pointed sigmoids are 80–115 µm in length, and are scattered in the body wall and not clustered. Probably the two-pointed sigmoids are underdeveloped typical sigmoid with open-eye. In the tentacles there are straight and C-shaped rods, sometimes branched at the ends, 70–90 µm in length. It is assumed that atypical two-pointed sigmoid ossicles may have been originated due to deviating from the usual course of sigmoid development in the middle stages. Scoliorhapis stepanovi resembles S. lindbergi. A key for species of Scoliorhapis is provided.
A new species of Phyllodytes (Anura: Hylidae) from the Atlantic Rainforest of southern Bahia, Brazil
Authors: VÖRÖS JUDIT , DIAS IURI RIBEIRO , SOLÉ MIRCO
Published: October 2017

We describe Phyllodytes amadoi sp. nov., a species of treefrog from the Atlantic Rainforest of southern Bahia, Brazil. The new species can be diagnosed by its small body size (SVL 15.6–23.0 mm) and advertisement call with high dominant frequency (3.789–4.306 Hz). It is known from one locality in the Private Reserve of Natural Heritage Ararauna, in the municipality of Una (15° 18' 38.3" S, 39° 9' 55.9" W, 96 m a.s.l.).
Bimanual Coupling and the Intermanual Speed Advantage
Authors: Crites Michael J. , Gorman Jamie C.
Published: October 2017

This study investigated previously observed differences in speed when completing a two-handed task either bimanually (i.e., the normal, two-handed mode) or intermanually (i.e., when such tasks are performed with different peoples’ hands). When comparing these two manual “coordination modes,” a phenomena referred to as the intermanual speed advantage has been observed. While various research domains have reported the intermanual speed advantage (i.e., a “mode effect”), recent research suggests that the observed difference in performance may depend on fundamental bimanual limitations that are not observed when using the intermanual coordination mode. To investigate the intermanual speed advantage, a task was constructed to exploit a hypothesized bimanual limitation that may underlie this mode effect: bimanual coupling. Results showed a replication of the intermanual speed advantage and higher between-hand coupling during bimanual performance. Subsequent analyses suggests that speed during two-handed tasks may be facilitated by decoupled movement of the limbs, regardless of coordination mode.
Challenges when university researchers work collaboratively with industry in aviation safety: Why can’t we all just get along?
Authors: Fothergill Selina
Published: October 2017

Increasing interest exists for collaboration between university researchers and industry partners, however there have been few attempts to analyse the nature of these collaborations (Calvert & Patel, 2003). This presents a void in terms of the challenges present, as well as the mutual benefits. In order to identify the most salient concerns, six researchers from Australian universities, who have worked with corporations on aviation research projects, and eight individuals from industry, who have worked with academic collaborators on aviation research projects, were sampled. Survey respondents were also asked what benefits were realized from the cross academic/industry partnerships. Findings revealed the most frequent challenges that each group face, as well as the primary benefits. Qualitative comments are provided to illustrate the three most common challenges and benefits. Results provide both valuable insights into the common predicaments when conducting applied aviation research and an indication as to which areas to focus on, in order to improve future collaborations. Further analyses are being conducted to identify challenges within other safety domains and concerns that may exist within international partnerships.
Evaluating effects of workload on trust in automation, attention allocation and dual-task performance
Authors: Yuan Zhang Meng , Jessie Yang X.
Published: October 2017

This study aimed to examine how workload and automation aid type affected operators’ trust in automation, attention allocation and dual-task performance. With a simulated surveillance task, participants monitored the picture steaming from an unmanned ground vehicle (UGV) while planning the paths of two unmanned aerial vehicles (UAVs). The analysis of experimental results indicated that workload affected operators’ attention allocation and dual-task performance, but not their trust in automation. As workload increased, attention allocation on the automated task decreased and on the concurrent task increased. Moreover, an increasing workload led to longer response time for the automated task. For the concurrent task, higher workload harmed task performance accuracy but resulting in shorter response time.
Is visual search strategy different between level of judo coach when acquiring visual information from the preparation phase of judo contests?
Authors: Robertson Paul J , Callan Mike , Nevison Charlotte , Timmis Matthew A
Published: October 2017

Judo contests are complex situations for coaches observing them. Identifying where judo coaches look (i.e. their visual search strategy) when observing contests can help identify visual information they may use to inform coaching decisions. The current exploratory study investigated the visual search strategies of elite, sub-elite, and non-judo coaches when observing the preparation phase (viewed from video footage) of elite-level judo contests. Participants' eye movements were recorded using a mobile eye-tracker. Participants were instructed to provide verbal coaching instructions to improve a specified judoka's (judo athlete) performance at set times during the footage. Elite coaches fixated significantly more frequently and longer on the specified judoka's upper body ( p < 0.05) compared to the opponent's upper body and other key areas within the display. Sub-elite and non-judo coaches demonstrated no significant difference in the frequency or overall length of fixation between the judokas' upper bodies. The visual search strategy of elite judo coaches may have been a purposeful attempt to obtain accurate information about the judoka's attacking intentions early within the contest. This visual search strategy can be attributed to elite judokas' attempting to disguise their attacking intentions. Furthermore, elite coaches may have used the specified judoka's upper body as a visual pivot.
Ways of Reading
Authors: Williams Jeffrey J.
Published: October 2017

“Ways of Reading” presents an interview with Sharon Marcus in which she discusses the influential and controversial concept of “surface reading.” The interview covers the genealogy of the concept, its difference from symptomatic reading, its relation to description, and other issues in contemporary method in literary criticism. It also addresses some of the debate about the concept and offers one revision. Additionally, the interview also surveys Marcus's influential work in comparative literature, notably on the spaces in fiction in French and English literature in her book Apartment Stories and the homosocial relations among women in Victorian literature in her book Between Women. Last, it discusses coediting the new journal Public Books.
Gender differences in the prevalence of nonalcoholic fatty liver disease in the Northeast of Thailand: A population-based cross-sectional study
Authors: Summart Ueamporn , Thinkhamrop Bandit , Chamadol Nittaya , Khuntikeo Narong , Songthamwat Metha , Kim Christina Sunyoung
Published: October 2017

Background. Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease. A large number of studies have strongly described larger proportions of men being afflicted with NAFLD than women; however, recent studies investigating the role of gender and NAFLD have exposed the contrary.

Methods. This cross-sectional study utilized data from the baseline survey of an ongoing cohort study called the Cholangiocarcinoma Screening and Care Program (CASCAP), conducted in the northeastern region of Thailand between March 2013 and September 2015. Information regarding socio-demographic, including gender, was collected using a standardized self-administered questionnaire. NAFLD was diagnosed with ultrasonography by board-certified radiologists. A binomial regression was used for estimating the prevalence differences, odds ratios (OR) and the 95% confidence intervals (CI) of NAFLD between men and women.

Results. A total of 34,709 participants (27,073 females and 7,636 males) were recruited. The prevalence of NAFLD in women was 22.9% (95% CI: 22.5 to 23.5), whereas it was only 18.3% (95% CI: 17.4 to 19.2) in men. After adjusting for age and presence of diabetes mellitus and other underlying diseases, the prevalence was significantly higher in women, with adjusted prevalence difference of 4.2% (95% CI: 3.2 to 5.2) and adjusted OR of 1.3 (95% CI: 1.2 to 1.4). Women had a higher prevalence of NAFLD than men in all age groups and the largest difference was found in those aged 56-60 years (prevalence = 27.4% versus 21.2%; adjusted prevalence difference = 9.4%; 95% CI: 7.9 to 10.9; adjusted OR = 1.8; 95% CI: 1.8 to 2.0).

Conclusion. NAFLD is more likely to affect women more than men, in particular, among the population 56-60 years of age, which is the post-menopausal transitional period. Therefore, post-menopausal women should be the target for interventions or further investigation for NAFLD.
Cultura organizacional e qualidade em serviços em instituição de saúde pública portuguesa
Authors: Lourenço Paulo José de Freitas , Cardoso Ilda Maria Morais Massano , Matos Fátima Regina Ney , Hermann Nodari Cristine
Published: October 2017

Nos últimos anos, têm proliferado em Portugal investigações sobre a cultura organizacional e a gestão da qualidade, quer no setor industrial, quer no setor da saúde. Esta investigação por meio de um estudo de caso consistiu na aplicação de dois questionários, o Organizational Culture Assessment Instrument (OCAI) e o SERVPERF, no Hospital Distrital da Figueira da Foz tendo em vista identificar a tipologia da cultura organizacional e verificar uma possível relação com as dimensões da qualidade percecionadas pelos colaboradores desta instituição de saúde. Os resultados obtidos demonstram que a tipologia de cultura organizacional que obteve maior pontuação foi a cultura de mercado. Relativamente à perceção das dimensões da qualidade, nos serviços, pelos clientes internos, verificou-se que a dimensão confiança que obteve a pontuação mais elevada, correlacionando-se estatisticamente com as quatro tipologias de cultura, clã, adocrática, burocrática e de mercado.
Satisfação, conflitos e engajamento no trabalho para professores do ensino médio
Authors: Pauli Jandir , Tomasi Manueli , Gallon Shalimar , Coelho Elenise
Published: October 2017

O presente artigo tem como objetivo descrever a relação entre conflitos intragrupais, engajamento e satisfação com o trabalho para professores da Rede Pública do Ensino Médio. Trata-se de uma pesquisa quantitativa-descritiva de corte transversal com a aplicação de 201 questionários de tipo survey a professores de dez escolas públicas. As análises mostraram que os conflitos de ordem afetiva influenciaram diretamente na percepção de Satisfação no Trabalho. Além disto, a satisfação com a natureza do trabalho está diretamente relacionada com o engajamento e esta relação é moderada pela percepção de conflitos intragrupais. Os resultados encontrados sugerem que para os professores os conflitos são importantes vetores do engajamento, enfatizando a necessidade de promover vivências positivas nas atividades laborais em escolas preservando a natureza do trabalho docente.