bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy Comparison of Targeted Systemic Monotherapies Including Lebrikizumab for Moderate-to-Severe Atopic Dermatitis: a Network Meta-Analysis
Authors: Silverberg Jonathan , Bieber Thomas , Paller Amy , Beck Lisa , Kamata Masahiro , Puig Luis , Wiseman Marni , Ezzedine Khaled , Foley Peter , Johansson Erin , Dossenbach Martin , Akmaz Bülent , Casillas Marta , Karlsson Andrei , Chovatiya Raj
Published: January 2024

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 2–7% of adults globally, with 30% experiencing moderate-to-severe disease. Although several treatments for moderate-to-severe AD are available, the efficacy of many treatments has not been compared in head-to-head trials. Using a network meta-analysis (NMA), we evaluated the relative efficacy between lebrikizumab, an emerging biologic, and approved targeted systemic treatments for AD.

Methods: Double-blind, randomized, placebo-controlled clinical trials (systemic monotherapy-only) for moderate-to-severe AD in adults (≥18 years) and adolescents (≥12 years to ≤18 years) published before April 2023 were identified in a systematic literature review. Data were extracted for short-term (12–16 weeks) efficacy outcomes (Investigator’s Global Assessment [IGA] 0/1 with ≥2-point improvement from baseline and the Eczema Area and Severity Index [EASI]) and patient-reported outcomes (Peak Pruritus Numeric Rating Scale [PP-NRS] with ≥4-point improvement from baseline). Bayesian NMAs were performed using random-effects models, with baseline-risk adjustment. Key estimates from the NMAs included pairwise differences between all treatments and absolute response rates for each treatment.

Results: Twenty-three clinical trials were included. For % achieving IGA 0/1, at 12–16 weeks, the estimated response rates (posterior median and 95% credible interval) for each of the treatments were: upadacitinib 30 mg 56% (46–65%), upadacitinib 15 mg 42% (32–50%), abrocitinib 200 mg 38% (31–45%), lebrikizumab 250 mg 32% (25–40%), dupilumab 300 mg 32% (24–39%), abrocitinib 100 mg 26% (20–32%), tralokinumab 300 mg 18% (13–22%), baricitinib 4 mg 17% (10–25%), baricitinib 2 mg 16% (10–22%), and placebo 6% (5–8%). Similar trends were observed for the EASI and PP-NRS responses at 12–16 weeks.

Conclusion: This 16-week NMA analysis shows that lebrikizumab had a similar response rate to dupilumab, the most widely used targeted systemic therapy for AD, and may represent a valuable treatment alternative for moderate-to-severe AD.
Matching-Adjusted Indirect Comparison of the Efficacy of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis Beyond Week 16
Authors: Torres Tiago , Sohrt Petersen Anne , Rosso Aldana Mariela , Moreira Taveira Christian , Carrascosa José Manuel
Published: January 2024

Introduction: Tralokinumab and dupilumab are both licensed for the treatment of moderate-to-severe AD. However, to date no head-to-head studies or indirect comparisons of their efficacy beyond week 16 have been conducted.

Objective: To conduct a matching-adjusted indirect comparison (MAIC) comparing the efficacy of tralokinumab and dupilumab beyond week 16, both used in combination with topical corticosteroids.

Methods: An unanchored MAIC was conducted using individual patient data (IPD) from the ECZTRA 3 tralokinumab trial and aggregate data from the LIBERTY AD CHRONOS dupilumab trial. IPD were selected by applying the inclusion criteria from the LIBERTY AD CHRONOS trial, then weighted to match summary baseline characteristics – age, sex, race, BMI, disease duration, EASI, DLQI, IGA and SCORAD– of patients treated with dupilumab. Tralokinumab efficacy outcomes at week 32 were compared with dupilumab data at week 32 (EASI and IGA only) and week 52.

Results: Baseline characteristics of the matched tralokinumab arm were well balanced with the dupilumab arm. Tralokinumab and dupilumab showed comparable efficacy across all endpoints. The matched proportions of patients achieving IGA 0/1 were larger for tralokinumab patients at week 32 (49.9%) compared with dupilumab patients at week 32 (39.3%) and week 52 (36.0%). The matched differences in IGA 0/1 at weeks 32 and 52 were 10.6% (95% CI: −2.9%, 24.0%; p = 0.12) and 13.9% (95% CI: 0.6%, 27.3%; p = 0.04), respectively. For EASI 75, the proportion of responders was equivalent for tralokinumab and dupilumab (both 71.9%) at week 32 (difference 0%; 95% CI: −12.2%, 12.3%; p = 1.00). The proportion of EASI 75 responders was numerically lower for dupilumab (65.2%) at week 52 compared with tralokinumab at week 32, giving a difference of 6.8% (95% CI: −5.9%, 19.5%; p = 0.3).

Conclusion: These results confirm broadly similar efficacy for tralokinumab and dupilumab beyond week 16.
Laboratory Parameters in Adolescent Patients Aged 12–17 with Moderate-to-Severe Atopic Dermatitis Treated with Tralokinumab Up to Week 52: Results from the Phase 3 ECZTRA 6 Trial
Authors: Paller Amy , Cork Michael , Hong Chih-ho , Soong Weilly , Schneider Shannon , Lo Hannah , Pedersen Line Rosendahl Meldgaard , Vacko Emilia , Wollenberg Andreas
Published: January 2024

Introduction: Tralokinumab, a high-affinity, monoclonal antibody that targets IL-13, is approved in the EU and Canada for adolescents (aged ≥12 years) with inadequately controlled moderate-to-severe atopic dermatitis (AD), and it does not require laboratory monitoring. The phase 3 ECZTRA 6 (NCT03526861) clinical trial demonstrated efficacy and safety up to 52 weeks in that population.

Objective/Purpose: To further characterize the safety profile of tralokinumab by evaluating laboratory parameters of adolescents in the ECZTRA 6 trial.

Methods: ECZTRA 6 subjects received tralokinumab 150mg (n=98), 300mg (n=97) or placebo (n=94) every 2 weeks (Q2W) from week 0–16 after a loading dose at week 0 (twice the subsequent dose), and then randomized to maintenance [original tralokinumab dose either Q2W or every 4 weeks (Q4W) or placebo Q2W] or open-label (tralokinumab 300mg Q2W) until week 52. Laboratory parameters included hematology, serum biochemistry, and urinalysis throughout the trial (weeks 0, 8, 16, 28, and 52).

Results: Overall (n= 289 subjects), laboratory baseline parameters were similar across treatment groups. Mean and median changes of most hematology parameters showed minor fluctuations within the normal ranges through week 52, except for eosinophils. At baseline, elevated mean eosinophil counts (>0.5 109/L) were observed for 40.8% (tralokinumab 150mg), 48.5% (tralokinumab 300mg), and 43.6% (placebo) of subjects in each respective treatment group. Some tralokinumab-treated patients had small transient increases in eosinophils (maximum mean change from baseline 0.2×109/L) before week 16. Continued treatment with tralokinumab or placebo did not correspond with further increase in eosinophil levels over time, and no adverse events of eosinophilia were reported. Mean levels of most biochemistry parameters, including electrolytes, renal and liver function parameters, and lipid panel, were within normal range at baseline, and mean and median changes showed minor fluctuations within normal ranges in all treatment arms. Mean lactate dehydrogenase levels were around or above the upper limit of normal at baseline and decreased to within the normal ranges during the trial across all groups. Overall, no clinically meaningful differences were observed in hematology, biochemistry, or urinalysis parameters between active treatment groups or placebo.

Conclusions: Similar to findings in adult trials, no meaningful changes in laboratory parameters were observed in adolescents through week 52 with tralokinumab treatment. No routine laboratory monitoring is needed for adult or adolescent AD patients treated with tralokinumab.
Patient and Caregiver Perception of Antibiotics and Antibiotic Resistance in the Context of Managing Acne Vulgaris (AV), and Patient Global Assessment (ptGA) of AV Among Patients Administered Sarecycline in US Clinical Practices: Results from PROSES Study
Authors: Hebert Adelaide , Harper Julie C. , Graber Emmy , Rieder Evan A. , Fried Richard G. , Stein Gold Linda , Alexis Andrew F. , Kircik Leon , Del Rosso James , Narayanan Siva , Koscielny Volker , Kasujee Ismail , Baldwin Hilary
Published: January 2024

Objectives: To evaluate perceptions about antibiotics and antibiotic resistance among adult patients and caregivers of pediatric patients with AV, and ptGA of AV, in the cohort of AV patients administered sarecycline in community practices across the U.S.
Methods: A single-arm, prospective cohort study (PROSES) was conducted with moderate-to-severe non-nodular AV patients >9 years who were prescribed sarecycline in real-world community practices in the US. At baseline, adult patients and caregivers of pediatric patients with AV were individually asked about their concerns about using (self, or for child, respectively) antibiotics for AV, and the concerns about antibiotic resistance; responses were on a 5-point likert scale of 0 (not at all) to 4 (extremely). ptGA of AV was assessed on a 5-point likert scale of (0 (clear), 1 (almost-clear), 2 (mild), 3 (moderate), 4 (severe)) at baseline and week-12.
Results: A total of 253 AV patients completed the study (adults 60.08%; pediatric 39.92%). Regarding concerns about antibiotics to manage AV, 20.39% of adult AV patients and 31.68% of caregivers (of pediatric AV patients) were somewhat/moderately/extremely concerned; 24.34% and 33.66% of adults and caregivers respectively were slightly concerned, and 55.26% and 34.65% of adults and caregivers respectively were not at all concerned. Regarding concerns about antibiotic resistance, 27.63% and 34.65% of adults and caregivers respectively were somewhat/moderately/extremely concerned; 25.66% and 34.65% of adults and caregivers respectively were slightly concerned, and 46.71% and 30.69% of adults and caregivers respectively were not at all concerned. On ptGA of AV, 59.29% of patients reported clear/almost clear at Wk-12.
Conclusion: Within the study cohort administered sarecycline, a narrow-spectrum, tetracycline-derived antibiotic, adult patients, and caregivers of pediatric patients expressed less concerns about antibiotics or antibiotic resistance at baseline; majority of patients reported clear/almost clear AV after 12 weeks of sarecycline treatment.
Overview of the Safety Profile From Efgartigimod Clinical Trials in Participants With Diverse IgG-Mediated Autoimmune Diseases
Authors: Sholzberg Michelle , Gwathmey Kelly , Broome Catherine M. , Goebeler Matthias , Murai Hiroyuki , Bata-Csörgo Zsuzsanna , Newland Adrian , Ulrichts Peter , Kerstens Rene , Guptill Jeffrey T. , Agha Sofiane , Jiang Ming , Howard Jr James F.
Published: January 2024

Background
Efgartigimod is a first-in-class, human immunoglobulin-G (IgG) Fc fragment that inhibits the neonatal Fc receptor (FcRn) and outcompetes endogenous IgG binding. FcRn inhibition by efgartigimod is a rational therapeutic option for IgG-mediated autoimmune disorders, including immune thrombocytopenia (ITP).
Aims
To determine the safety profile of efgartigimod for a variety of IgG-mediated autoimmune disorders, including ITP.
Methods
Intravenous efgartigimod safety was assessed in a phase 3 (ADVANCE) trial in ITP. It was also evaluated in generalized myasthenia gravis (gMG) in phase 2 and 3 (ADAPT) trials and a 3-year open-label extension (ADAPT+) along with an open-label phase 2 trial in pemphigus. Varying dosing regimens of efgartigimod (10-25 mg/kg) were used, including cyclical (gMG) and continuous weekly dosing (ITP, pemphigus).
Results
Across all indications and doses studied, efgartigimod demonstrated a consistent safety profile, with comparable treatment emergent adverse event (TEAE) rates to placebo (ADVANCE 93.0% efgartigimod vs. 95.6% placebo; ADAPT 77.4% efgartigimod vs. 84.3% placebo; 85% of participants in open label pemphigus study). Most TEAEs across studies were mild to moderate in severity. Discontinuation rates due to adverse events were low across studies (3.5% efgartigimod vs. 2.2% placebo in ADVANCE; 3.6% efgartigimod vs. 3.6% placebo in ADAPT; 3% in pemphigus). No increase in TEAE incidence rates or infections with repeated efgartigimod cycles (up to 19) in ADAPT+ was observed. In ADVANCE, no thromboembolic TEAEs were reported. Efgartigimod did not impair participant ability to generate new specific IgG responses to non-live vaccines, regardless of the timing of vaccinations however, there were transient reductions in specific IgG titers observed.
Conclusions
Efgartigimod was generally well tolerated across indications and doses studied. Most TEAEs, including infections, were mild or moderate in severity and did not increase in frequency with recurrent dosing. Non-live vaccine responsiveness was preserved. There were no thromboembolic events in those treated for ITP.
Manajemen PAUD
Authors: Nabila Restu , Tri Utami Dian
Published: January 2024

This research was conducted with the background of government policy demands regarding the management of PAUD standards. The implementation of PAUD management is one of the benchmarks of success of an ongoing PAUD institution. Therefore, good PAUD management will be able to realize a quality PAUD institution. This research is a descriptive qualitative study conducted in PAUD Sekato, Marison Village, Minas District, Siak Regency. The purpose of this research is to describe in general the implementation of PAUD management. This study uses qualitative research methods aimed at field research. The type of data used is data obtained from observations, interviews, and documentation. The results showed that the management of Sekato PAUD has not been fully implemented, but there are supporting and inhibiting factors that influence the management of PAUD management.
Les critères de l’art au risque du numérique. L’œuvre-réseau
Authors: Colas-Blaise Marion
Published: January 2024

Quels sont les critères de l’art dans le cas d’une œuvre numérique ? Dans cet article, il s’agit de montrer que les critères de l’art traditionnels doivent être questionnés, voire dépassés, quand l’attention se porte non seulement sur la matérialité de l’œuvre numérique, sur sa texture, mais encore sur le geste et le processus techniques, qui peuvent être qualifiés de beaux, plutôt que sur l’objet esthétique lui-même. Le mouvement est accentué par les NFT (Non-fungible tokens, jetons non fongibles) : nous visons à vérifier l’hypothèse qu’en étant déployés sur des blockchains et impliqués dans des échanges de droits de propriété, ces derniers mettent en avant des modes inédits d’acquisition, de stockage et de consultation, qui font patrimoine à leur tour. Plus particulièrement, on se demandera en quoi l’art contemporain prépare et annonce l’art numérique. Il s’agit également de distinguer l’œuvre-réseau numérique du réseau scientifique.
Chevauchements art - street skate : les conditions d’existence d’un « méta-mode » artistique
Authors: Lenoël Anne-Cécile
Published: January 2024

Cet article s’intéresse aux modalités de l’agir et du créer du street skate. Nous considérons que les pratiques des skateurs possèdent les temporalités d’une praxis et d’une aesthesis qui interfèrent de manière plurielle dans l’urbain. Le street skate ne conçoit pas que des espaces alternatifs (Lenoël 2016), il tisse des liens ténus avec les champs de l’art. Par une approche transversale skate-art, nous recherchons des marqueurs poïétiques des « choses artistiques » du skateboard. Plus que les limites, nous observerons ces phénoménalités artistiques par le prisme de la notion de chevauchement. Celle-ci désigne en effet une zone interstitielle signifiante pour étudier la densité syntaxique et sémantique que le skateboard peut donner à la ville.
AN ANALYSIS OF CUSTOMER PERCEPTION ON SELF-ORDERING KIOSK OF FASTFOOD RESTAURANTS IN SAN PABLO CITY, LAGUNA
Authors: Dela Peña Gladiewin B. , Aquino John Matthew
Published: January 2024

Self-ordering kiosks are increasingly being used in fast-food restaurants due to their efficiency and convenience. However, little is known about how consumers perceive this technology and how their perception affects their willingness to use it. This study aimed to address this gap by answering five questions related to self-ordering kiosks in fast-food restaurants in San Pablo, Laguna. The study used a survey questionnaire and Technology Acceptance Model to evaluate how customers view self- ordering kiosks. Statistical treatments such as mean frequency, Kruskal Wallis H-Test, and effect size were used to analyze the data. The results showed that majority of the 300 respondents found self-ordering kiosks useful and easy to use, preferring them over ordering from staff. The study found that customer perception on self-ordering kiosks had a significant effect on the intention to use the system. The demographic profile of respondents was analyzed, and the study found that 59% of the respondents were male aged 21 to 30. Despite the positive findings, the study identified several obstacles, including technical difficulties, security concerns, and accessibility issues, that must be addressed. The study proposed technology enhancements such as headphone ports, bilingual interfaces, and digital payment options to enhance the accessibility and convenience of self-ordering kiosks in restaurants. The study findings can be used for market segmentation analysis and the development of targeted marketing strategies for different demographic groups. The study highlights the importance of understanding customer perceptions of self-ordering kiosks to improve customer satisfaction and increase adoption of this technology in fast-food restaurants.
EXAMINING OPERATION-BASED TANGIBILIZATION FACTORS AND THEIR IMPACT ON PATRONAGE OF TELECOMMUNICATION PRODUCTS IN AKWA IBOM STATE, NIGERIA: A MULTIPLE REGRESSION ANALYSIS
Authors: Udom Aniediabasi James , Etuk Samuel G.
Published: January 2024

This research aims to examine the impact of operation-based tangibilization factors, such as the cleanliness of service stores, the physical appearance of employees, the visual appeals of service providers, the customer service store, and the visual appeal of materials associated with service providers, on the patronage of telecommunication products in Akwa Ibom State, Nigeria. We established a research hypothesis to guide the study. The study employed a survey research design technique and gathered data from primary sources through the administration of a questionnaire. The respondents consisted of 384 individuals who were users of telecommunication products. The researchers utilised multiple regression analysis to examine the formulated hypothesis. The results of the study indicate a statistically significant relationship between the tangibility dimensions, including the neatness of the service store, employee physical appearance, the visual appeal of service providers’ customer service stores, the visual appeal of materials associated with the service provider, and the patronage of telecommunication products in Akwa Ibom State, Nigeria.. A regression coefficient of 0.743 supports this relationship. Based on the findings and conclusions of this study, it is advisable to ensure that the physical environment, facilities, and infrastructure of the company consistently reflect the values and principles of the organisation.
STRATEGIC ANALYSIS OF CORPORATE WITH EMPHASIS ON FINANCIAL PERFORMANCE
Authors: Lal Ambashtha Kanahaiya , Kumar Singh Manoranjan , Dey Rajesh
Published: January 2024

This paper has the objective of performing complete analysis of Infosys, which is a leading IT firm of India. Through the study, it can be said that Infosys has been growing consistently in the past and trends suggest that it will keep on growing in the future as well. The revenue and operating profit has shown a positive trend. Infosys has been able to benefit from constantly growing market size and exports of the Indian IT Industry. Infosys generate most of its revenue from Energy & Utilities and Manufacturing. As the total industry size of IT has been increasing, Infosys total revenue has been increasing as well. Same can be said about IT exports.
DIGITAL FINANCIAL LITERACY PLATFORMS AND THEIR IMPACT ON NIGERIAN SECONDARY SCHOOL STUDENTS' TRANSITION TO UNIVERSITY: A REVIEW
Authors: Olanipekun Hassan Azeez , Onunka Tochukwu , Abitoye Oluwabosoye , Oriji Oluwafunmilola , Daraojimba Chibuike
Published: January 2024

This review paper examines the landscape of digital financial literacy platforms in Nigeria and their effects on secondary school students’ transition to higher education. These platforms are essential educational resources because they provide students with a wealth of financial knowledge and skills through interactive features and various financial content. The paper’s first section overviews the difficulties these platforms face, such as restricted internet access, a lack of devices, linguistic diversity, and long-term funding. These challenges can hinder the effectiveness and accessibility of digital financial literacy education in Nigeria. Despite these challenges, the future of these platforms is promising. The paper identifies key future directions, such as infrastructure development, device provision, multilingual content, and sustainable funding models, to address these challenges and make digital financial education more inclusive and effective. The impact of digital financial literacy platforms on secondary school students is examined, focusing on how these tools improve students’ financial knowledge, decision-making, and behavior. Exposure to these platforms equips students with financial awareness, decision-making skills, and the confidence to navigate the financial challenges they will encounter as they transition to university and adulthood. In conclusion, digital financial literacy platforms in Nigeria can potentially empower a generation of financially literate individuals. We can work toward a future where all students, regardless of background or location, have equal access to high-quality financial education by comprehending their difficulties and pursuing the necessary future directions.
PRECISION AGRICULTURE: REVIEWING THE ADVANCEMENTS, TECHNOLOGIES, AND APPLICATIONS IN PRECISION AGRICULTURE FOR IMPROVED CROP PRODUCTIVITY AND RESOURCE MANAGEMENT
Authors: Sharma Shikha
Published: January 2024

Precision agriculture is a rapidly advancing field that combines advanced technologies and data analytics to improve crop productivity and resource management. This article reviews the advancements, technologies, and applications in precision agriculture. It explores the role of sensing technologies, such as remote sensing, ground-based sensors, and GPS/GIS applications, in data collection and analysis for informed decision-making. The article also examines the impact of variable rate technologies, including variable rate seeding, nutrient application, and irrigation, on optimizing input usage and improving crop performance. Furthermore, it discusses the integration of precision crop management techniques, such as remote sensing, artificial intelligence, and the Internet of Things (IoT), in enhancing farming practices. While precision agriculture offers significant benefits, challenges related to cost, accessibility, data management, and education need to be addressed. It is crucial to overcome these challenges to fully harness the potential of precision agriculture for sustainable and efficient food production. By acknowledging and addressing these challenges, farmers and stakeholders can work towards the widespread adoption of precision agriculture, leading to improved crop productivity, resource management, and environmental sustainability.
EFFECT OF STORAGE CONTAINER ON KENAF SEED QUALITIES
Authors: Islam Ariful , Al-Mamun Md. Shamim- , Miah M. A. Rashid , Jahan Israt , Sultana Afroza , Uddin Md. Jalal , Sarder Hemayet Uddin
Published: January 2024

Kenaf seeds lose their ability to germinate during storage, leading to a lack of quality seeds compared to planting requirements, hindering the expansion of kenaf cultivation in Bangladesh. The effects of different storage containers on the germination, field emergence moisture content and 100 seed weight of kenaf seeds of three varieties were studied during a 4-month storage period from mid-January 2022 to mid-May 2022 in a room. Four different containers viz. C1=A plastic pot, C2=a polythene bag, C3=a cloth bag and C4=an earthen pot are used to store kenaf seeds. Three varieties, V1=HC-95, V2=HC-2 and V3=BJRI Kenaf-3 were used in this experiment. This experiment revealed that the percentage of germination and field emergence of all three varieties were reduced with increasing the storage time. On the other hand moisture content and 100-seed weight of three selected varieties were increased with increasing the storage period. Among the four containers it was observed that after 120 days of storage germination percentage was maximum for plastic pot (81.6%) followed by polythene bag (80.6%), cloth bag (58.6%) and minimum for earthen pot (56.0%). Similarly in field emergence the highest result found for plastic pot (72.3%) and lowest for earthen pot (53.3%). On the other hand the highest moisture content and 100 seed weight were recorded in cloth bag (21.1%) and 4.7g in earthen pots respectively and the lowest moisture content (10.4%) and 100 seed weight (3.26%) in plastic pots. Germination rate at 120 DAS was recorded maximum in HC-95 (70.2%) and minimum in BJRI Kenaf-3 (67.7%). The highest filed emergence at 120 DAS was found in HC-2 (63.0%) and lowest in BJRI Kenaf-3 (61.3%). The highest moisture content and 100-seed weight at 120 DAS were obtained in HC-2 (15.8%) and BJRI kenaf-3 (4.04%) respectively. The results reveal that the quality of kenaf seeds decrease with increase the storage time.
https://rfna.com.my/archive/2rfna2023/2rfna2023-71-77.pdf
Authors: Pandey Menuka , Raj Awasthi Hemant , Subedi Roshan , Joshi Kamal
Published: January 2024

The success of System of Rice intensification (SRI) has been extrapolated to numerous crops in the name of System of Crop Intensification (SCI). Similar to SRI, SCI practices tend to have beneficial effects, especially on the performance of tillering crops by optimizing tiller production. Therefore, a field experiment was conducted at a farmer’s field in Sundarbazar, Lamjung from July 2018 to January 2019 to evaluate the influence of SCI practices on the performance of finger millet. The experiment was laid out in split plot design with three replications, comprising five varieties (Okhle-1, Dalle-1, KabreKodo-1, KabreKodo-2 and Local) as main plot factors and planting methods (Direct Sowing (DS) at 20 cm ×10 cm, Conventional Transplanting (CT) at 10 cm × 10 cm with 30 days old seedling and System of Crop Intensification (SCI) at 25 cm × 25 cm with 15 days old seedling) as sub-plot factors. Growth attributes like plant height, tillering habit and growth rates were recorded maximum in SCI method resulting in highest yield (2.75 tons/ha). The yield obtained from CT and DS was 14.90% and 29.69% less than SCI. Kabrekodo-1 variety recorded maximum height at harvest and growth rate during both vegetative and reproductive phases also the yield of this variety was higher than other varieties. Thus, the study revealed Kabrekodo-1 as potential variety of the area and SCI as a better option to increase performance of finger millet.
DOES THE ACADEMIC ENVIRONMENT DEVELOP TEAMWORK EFFICIENCY AMONG STUDENTS?
Authors: LINCĂ Florentina Ionela , MATEI Florentina Lavinia
Published: January 2024

Teamwork skills are considered essential for all areas of a person’s life, so universities take them into account when designing their curricula. These skills are especially important if we are talking about humanities fields. However, little is known about how students’ factors can affect the process of developing teamwork skills. Consequently, our study proposes to fill this gap and to analyze the mastery of teamwork skills by higher education students, measured by the efficiency of working in a team, in relation to teamwork styles, but also with the number of courses whose content allows the development of these skills. One Hundred Ninety-Five female students participated in this study, with an average age of M = 31.5, a standard deviation of SD = 9.2. The participants filled out a questionnaire that measured the efficiency of teamwork and the styles of teamwork based on specialized literature. Also, the questionnaires were first applied in a pilot study in which 50 female students participated and the Cronbach’s internal consistency index was 0.8 for the first questionnaire and 0.77 for the second. The results showed that there are statistically significant correlations between teamwork efficiency, teamwork styles, and the number of courses in which the development of these skills is encouraged, p < 0.01. Moreover, we also noticed that the number of courses in which the development of these skills is encouraged has a mediating effect on the relationship between working styles in a team and the efficiency of working in a team, p < 0.01. These results can support teaching staff in higher education to adopt the most suitable educational methods for the development of teamwork skills, essential skills, especially for students in the humanities domains.
WHAT’S IN A-WORD? MAKING AN IMPACT BY INTEGRATING VIDEOS IN ONLINE ASSESSMENT
Authors: Pop Anișoara
Published: January 2024

This paper is an empirical descriptive and at the same time exploratory case study of using Google Forms (GF) with integrated video listening as part of an online formative assessment (FA) in English for Medical Purposes (EMP), with a group of 74 first-year undergraduate students in medicine (N = 74), to engage students and facilitate constant autonomous learning. The online FA was based on a segment of the movie entitled A-word – standing for Autism – and it checked the students’ application of medical vocabulary, language functions, doctor-patient interviewing, and symptoms of autism. The online formative assessment was compared with a traditional onsite listening FA in terms of administration and results. The onsite FA had a similar degree of complexity and was conducted with the same group of students – a segment from One Flew over the Cuckoo’s Nest, a classic on life in a psychiatric institution, within the same scope of neuropsychiatric conditions. The impact of online FA on students was measured with Mentimeter (https://www.mentimeter.com/). The results of this case study demonstrate that the GF-based FA of listening in EMP is an enhanced version of the traditional one. In traditional FA feedback was general and approximate while overall statistics were not automatically generated. Reaching a more refined picture of the overall and individual student performance with question breakdown in onsite FA required additional time investment, and consequently, remedial teaching could not take place immediately. Online FA was low-anxiety, highly participative, and user-friendly. It offered students timely feedback on their learning and teachers a faithful, automatic picture of individual and group performance for further remedial strategies. Likewise, the impact and attitude to online FA measured by Mentimeter were positive and were associated with increased autonomy, online delivery, engagement through professionally relevant content, and focus on learning rather than testing and grading.
THE ROLE OF THE SCHOOL-FAMILY PARTNERSHIP IN THE EMOTIONAL REGULATION OF STUDENTS TAKING THE BACCALAUREATE EXAMINATION
Authors: Enache Rodica Gabriela , Didoacă Mihaela Mirela
Published: January 2024

School anxiety belongs to the category of social anxiety disorders and has broader consequences on emotional development. If a student’s academic self-concept does not align with their academic goals (such as success on an assessment), this can cause anxiety. Students may then try to use strategies to reduce the level of anxiety they feel. The ability to cope adequately with difficult academic assessment situations plays a major role in emotional regulation and increasing students’ psychological well-being. Our objectives for the study were to assess the level of test anxiety and level of worry of 12th-grade students, the level of communication between the school and the families of students taking the Baccalaureate Examination, to identify associations between students’ test anxiety and family involvement in students’ preparation and emotional regulation.
Evaluating uniformity of seed distribution with an experimental seeder: solid sowing of lawn grasses
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, PLYAKA VALERY I.
Published: January 2024

Solid seeding should ensure uniform distribution of seeds over the cultivated area. The experimental seeder SV‑0.9, developed and improved by the authors, is equipped with a coil type seed-feeding device. It provides variable seed supply from each pair of coils of the seed-feeding device and ensures uniform seeding when following a straight path and a curved path. For solid sowing, it is necessary to provide uniform seed distribution over the cultivated area. For this purpose, two indicators can be used: the seeding uniformity factor and the average feeding area of a plant. The Gazon Bystriy lawn grass mixture was used to test the experimental seeder for determining the indicators of seed distribution uniformity. The tests were carried out under laboratory conditions. During the experiment, seeds were fed into the seed box and the seeding rate was set at 3.5 kg/100 m2 . Paper tape was marked into 10x10 cm squares and further divided into centimetre cells. The prepared tape was covered with glue. The seeds were sown on the sticky tape while the seeder was moving. The uniformity of seed distribution over the area was evaluated by counting the seeds in the square cells. According to the experiment results, it was found that the seeding uniformity factor ranged between 0.92 and 0.96, which corresponds to the indicators of GOST 31345‑2017, and the average feeding area per plant was 0.48 to 0.56 cm2. The laboratory results prove the possibility of solid sowing by the SV‑0.9 seeder at a seeding rate of 3.5 kg/100 m2
Eksplorasi Etnomatematika Masjid Agung Al-Muhtaram Kajen Kabupaten Pekalongan dalam Pembelajaran Matematika
Authors: Musbaiti  , Miftahurrahmah Rizqi , Nabila Zulfa , Fahmy Ahmad Faridh Ricky
Published: January 2024

Ethnomathematics exists in order to bridge between students and culture so that mathematics is easy to understand. This study aims to explore the relationship between mathematics and culture, especially at the Great Al-Muhtaram Kajen Mosque, Pekalongan Regency. This study used an ethnographic approach with data collection methods, namely observation by three observers and documentation. The results of the study show that there is ethnomathematics in mosques such as the concept of plane shapes, arithmetic sequences, and sets.
Aplikasi Zyra sebagai Media Belajar Bangun Ruang Sisi Datar
Authors: Andini Nanda Meilia , Rini Juwita
Published: January 2024

The purpose of this development research is to determine the level of validity, practicality, and effectiveness of the Zyra application based on the android mobile game and integrated Augmented Reality as a medium for learning to build flat-sided spaces for class VIII students. This study applies the ADDIE development model, uses data collection techniques in the form of interviews, documentation, questionnaires, and tests, and uses descriptive qualitative techniques as data analysis techniques. This research, which lasted for approximately four months, produced a learning application product that was declared valid with a score of 83.5% and 79.5, practical with a score of 83%, and effective with a score of 86.66% based on the results of the pre-test. and post-test.
Kekerasan Simbolik Era Digitalisasi Terhadap Perilaku Masyarakat Beragama Di Desa Tanen Kecamatan Rejotangan Kabupaten Tulungagung
Authors: Wakhidatus wakhidatus  , Sindi Kania  , A Zahid
Published: January 2024

With the development of social media in Indonesia, it is easier for everyone to channel opinions through internet networks. Many things can be obtained besides channeling opinions, for example as a space for information, education, politics, da'wah, entertainment, health and so on. The era of digitalization is one sign of the development of globalization in the field of technology that displays the face of novelty and sophistication by providing convenience for users. This study aims to determine the symbolic violence of the digitalization era on the behavior of religious communities in Tanen Village and the causal relationship it causes. This research method uses descriptive qualitative research with observation techniques and interviews with several religious communities in Tanen Village by linking the results of the analysis and previous research using Pierre Bourdieu's theory of symbolic violence. The results of this study indicate that with the advancement of this digital era, the religious community in Tanen Village experienced symbolic violence as evidenced by some of the behavior of the people in Tanen Village, Rejotangan District. Evidence of symbolic violence experienced by the community is shown by the behavior of the people of Tanen Village behavior in social media but is not based on religious guidance.
Upaya Kelompok Ektrimis Untuk Menunggangi Isu Palestina-Israel: Analisis Diskursus Terhadap Narasi Kelompok Pro-Khilafah
Authors: Nurhidayat nurhidayat
Published: January 2024

In Indonesia, as the country with the largest Muslim population in the world, there has also been a strong and massive reaction to what happened in Palestine. Ismail Fahmi, through his social network analysis on social media Twitter, found that the Palestinian-Israeli issue was in fact being ridden by pro-khilafah groups. This paper attempts to study pro-khilafah groups that are trying to ride on the Palestinian-Israeli issue. The approach adopted in this paper is qualitative by using the netnographic method. Netnography is the application of ethnography in cyber space to examine the culture and behavior that occur in computer-based activities. In the midst of this struggle for influence in the narrative of defense of Palestine, there is one small group which, if not observed closely, can freely raise a theme which is quite dangerous: the caliphate. This small group moves among other Palestinian support groups. The pro-khilafah narrative emphasizes elements of Islamic identity rather than humanitarian issues. He blatantly tried to draw a line of distinction between Judaism and Islam. From there, then the pro-khilafah activists entered into their ultimate goal, which is to promote the caliphate as a solution to the problems of the Palestinian people. The narratives built by the supporters of the caliphate are generally accompanied by the hashtags #khilafahsolusipalestina and #palestinaneedskhilafah. Widespread public support for Palestine is used by a few groups to smuggle their pro-caliphate agenda. This group, although small, has its audience, including women. The pro-khilafah promote war as an attraction for men who want action, and elements of the safety of Palestinian families, children and women for female audiences.
Abed Al-Jabiri's Epistemology of Intelligence: A Case Study of Interfaith Marriage In Indonesia
Authors: Sutono Agus , Noorzeha Fuad
Published: January 2024

Interfaith marriage/mixed marriage is currently an unresolved social polemic. It means that the marital status of different religions is still a hot topic of discussion because seeing the impact caused by interfaith marriages is very large. These impacts are child care, inheritance rights, child morals, and up to divorce. Often, interfaith marriages occur based on freedom of reasoning in religion. Thus, for people in an interfaith marriage, the perception of reason provides legal justification to strengthen the legality of interfaith marriages. Therefore, various efforts in interfaith marriages continue to be carried out in Indonesia. This research used the epistemology of Abed al-Jabiri, namely: Bayani, Burhani, and Irfani to emphasize reason as Idraku al- Sabab Wa al-Musabbab and reason as Bila Wasitah. This method is different from the epistemological methods of other figures such as Ibn Rushd and Ibn Khaldun. Thus, the researcher used al-Jabiri's epistemological trilogy as a method of thinking to see the freedom of reasoning in interfaith marriages. This research was qualitative research with heuristic methodical elements and used an epistemological approach. The heuristic method provides criticism of a certain paradigm so that the consequences of criticism become an alternative to a new paradigm. The results of this research were Abed al-Jabiri's criticism through an epistemological trilogy to provide limits on freedom of reasoning in interfaith marriages.
Contesting the Exegetical Approaches of Muhammad Abduh and Fazlur Rahman to the Qur’ān
Authors: Maghribi Hamdan , Hidayah Alfina
Published: January 2024

The exegetical approaches that Muhammad Abduh and Fazlur Rahman used to study the Qur’ān are this study’s main focus of discussion. The research is essential to enrich the literature of contemporary Islamic studies by contesting the two scholars’ interpretation approaches. This article will answer whether the contextualized interpretation model is still relevant today by comparing and contrasting Abduh and Rahman’s respective interpretive approaches and providing examples of the verses mentioned. Hence, this study is qualitative-library research, whereas data processing relies on content analysis and comparative methods. Nevertheless, reading Abduh and Rahman’s ideas within contemporary situations is still necessary because of its rational-contextual interpretation, which is compatible with modern society and needs.
The Movement of Postcolonialism by Kiai Sholeh Darat Against the Dutch Colonialism (Study of Social-Religious Decolonization in Java 19th and 20th Century)
Authors: Maulana Luthfi , Hak Nurul , Abdurahman Dudung
Published: January 2024

This study discusses the postcolonial movement of Kyai Sholeh Darat in fighting Dutch colonialism at the end of the 19-20 centuries. This study is interesting because so far there has been a physical resistance movement against colonial figures. This study finds Kyai Sholeh's postcolonial movement through his cultural approach. Methodologically, this research is included in the library research category to produce historical research studies based on postcolonial movements carried out by Kiai Sholeh Darat. From this it was found that the movement culture of Kiai Sholeh Darat in post-Java War 19th and early 20th century Java seen as a postcolonial spirit and identity, with evidence showing a tendency towards a series of domination colonial regime in various lines of life of the Javanese people. cultural movement Kiai Sholeh Darat reflects the identity of the postcolonial movement through movement literacy which is manifested by publishing writings in the pegon script and translating the Qur’an into Javanese as a form of resistanceagainst the colonial project that seeks to separate Java from Islam. Kyai Sholeh also carry out kyai regeneration as a form of forming religious cadres and nationalist and conducts education for the Javanese people with da'wa from village or city in Java.
Living Hadith of the Lazismu Movement and Its Influence on Indonesian Society
Authors: Romansyah  , Rahmanto Mukhlis , Zainuddin Mahli , Robani Anidah
Published: January 2024

Poverty is an essential issue for Muhammadiyah as a socio-religious and social organization in Indonesia. Poverty is caused by ignorance and underdevelopment and has occurred from the past to the present. To solve this problem, Muhammadiyah through Lazismu takes social action based on hadith. Muhammadiyah revives and implements hadith in the form of genuine assistance. This paper aimed to address the problem of poverty through Lazismu based on the hadith of social action. This research used qualitative scientific methods based on field research through observation, interviews, and library research. The results of this study indicated that the social activities carried out by Lazismu are a manifestation of tajdid/renewal and efforts to revive hadiths. The Lazismu assistance program includes direct assistance to the poor, natural disaster relief, educational issues, and the economy. Lazismu has a major influence on the welfare of the Indonesian people, especially the poor and underdeveloped and those affected by disasters. Poor and unemployed people receive productive alms assistance from Lazismu to facilitate their innovation and creativity in creating business opportunities that are able to develop and be sustainable.
Salawat Adhiya Ulami at the Jalsatul Itsnain Baa Alawy Bandung Assembly: Salawat as a Medicine for Peace of Mind
Authors: Nurjanah Dian Siti , Yumna  , Wasik Abdul , Hamid Mohammad Fahmi Abdul
Published: January 2024

This paper discusses the role of Salawat adhiya ulami on the peace of mind of the members of Majelis Jalsatul Itsnain Baa Alawy Bandung. This paper is field research with the object of research at Majelis Jalsatul Itsnain Baa Alawy in Katapang, Bandung, West Java Indonesia. This research uses descriptive methods and a phenomenological approach to obtain data, observation, interview, and documentation techniques were used. While analyzing the data qualitative analysis techniques. This study found that Salawat adhiya ulami is a strand of Salawat that contains the life history of the Prophet Muhammad from birth to death, and Salawat adhiya ulami is a medium for a congregation of the Jalsatul Itsnain Baa Alawy Assembly to express longing for the Prophet Muhammad. By using a Sufistic approach, it can be concluded that after reading Salawat adhiya ulami, a congregation of the Jalsatul Itsnain Baa Alawy Assembly gets peace of mind in carrying out daily life. So that with peace of mind, the congregation believes that they will be husnul khatimah at the end of their lives. This belief is based on the words of Allah; calm souls, return to God with a heart that is pleased, and enter My servants and enter My heaven.
Understanding The Phenomenon of Fake Crazy Rich and Fraudulent Investment in Indonesia from the Philosophy of Happiness in Hazrat Inayat Khan’s Sufism
Authors: Roswantoro Alim
Published: January 2024

The phenomenon of crazy rich as one of modern materialism and hedonism have poisoned the life of Indonesian’s younger generation in the current millennial era. They have been eroded by worldly pleasures. Tempted by the glamorous and luxurious lifestyle of crazy rich people, they were willing to flaunt the wealth of property that was not yet theirs. Many people have fallen victim to their fraudulent investments in Indonesia. They did it to being able to deceive many people for investing their money in their fraudulent investment businesses. Those who cheated or were cheated have actually been deceived by worldly pleasures. What they got were not real happiness, but fake happiness and even the misery and humiliation of life. This phenomenon is interesting to read from the perspective of Inayat Khan’s philosophy of happiness in his Sufism. Inayat Khan differentiates happiness from pleasure. The first term refers to a true happiness, while the second one refers to a pseudo happiness. The relationship between pleasure and happiness is that of falsehood and trueness. His conception is relevant to be used as a theoretical framework to analyse the phenomenon of fake crazy rich and fraud investment in Indonesia. The phenomenon shows the preference of young Indonesians to pursue the material and physical wealth as a measure of a successful life by all means, both good and bad. This, from the viewpoint of Inayat Khan’s philosophy of happiness, is a false fulfilment of life satisfaction.