bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection of Fatty Acids and Some Secondary Metabolites in Macadamia and Hazelnut Fruits and their Shells, with Studding the Physiochemical Properties of its Extracted Oil: A comparative Study
Authors: Altaee Rana T. , Aldabbagh May G , Rashan Aya I.
Published: August 2024

General Background: Nuts are widely recognized for their nutrient density, offering a rich source of beneficial fatty acids and antioxidant phytochemicals. Specific Background: Among these, macadamia and hazelnuts are popular for their unique compositions, yet direct comparisons of their nutritional and bioactive profiles remain limited. Knowledge Gap: Despite their recognized health benefits, comparative analyses of the fatty acid profiles, bioactive compositions, and physicochemical characteristics between these nuts are scarce. Aims: The study compared macadamia and hazelnut oils' fatty acid content, lipid-soluble vitamins, phenolic compounds, and physicochemical properties to enhance their functional applications. Results: The findings revealed that hazelnut oil exhibited a higher polyunsaturated fat content, particularly linoleic acid (22.8% vs. 18.25%), while macadamia oil contained significantly more vitamin E, contributing to superior antioxidant potential. Both oils demonstrated the presence of vitamins A, D, and K1, with notable concentrations of quercetin and rutin among other flavonoids. Novelty: This study is novel in its comprehensive comparative analysis of these two nuts, particularly in identifying the unique phenolic compounds in the nutshells, which are often discarded but show potential as nutraceuticals. Implications: Macadamia and hazelnut oils offer significant nutritional benefits, with compositional variations allowing for personalized bioactivity and culinary applications. Further research is recommended for human health promotion.
Highlights:
 

Hazelnut oil has more polyunsaturated fats; macadamia oil is richer in vitamin E.
Both nuts contain vitamins A, D, E, K1, and flavonoids.
Phenolic compounds in nutshells have potential as nutraceuticals.

 
Keywords: macadamia nuts, hazelnut oil, fatty acids, antioxidant phytochemicals, bioactive compounds
Environmental Changes of the Temirnik River in Rostov-on-Don
Authors: AL-Ghizzi Murooj Abbas Buhlool , Al-Janabi Zahraa Zahraw
Published: August 2024

General Background: The increasing anthropogenic impact on river ecosystems has raised concerns about water quality and its effects on surrounding communities. Specific Background: This study focuses on the Temirnik River, located in the northern part of the city, particularly assessing pollution levels in the beaches of "Druzhba" and "Surp Khash." Historical data from 2000-2001 and recent analyses from 2017-2019 reveal significant fluctuations in chemical and biological toxicity. Knowledge Gap: While previous studies have documented pollution levels, a comprehensive comparison of historical and recent data to understand long-term changes and community impacts remains insufficiently explored. Aims: This study aims to track changes in pollution levels over time, evaluate the chemical and biological toxicity, and assess the anthropogenic impacts on the Temirnik River. Results: Chemical analysis revealed increased hardness of water due to the accumulation of calcium and magnesium sulfates and chlorides. The river, heavily impacted by untreated industrial and municipal waste, showed high toxicity levels, especially in the years 2017-2019. Bioassays using Chlorella vulgaris, Raphanus sativus, and Daphnia magna confirmed these findings. Novelty: This study provides a detailed comparative analysis of historical and contemporary pollution data, highlighting the persistent and worsening impact of anthropogenic activities on the Temirnik River. Implications: The findings underscore the critical need for ongoing monitoring and intervention to mitigate pollution. They advocate for implementing effective cleaning operations and regulatory measures to protect water quality and community health.
Highlights:
 

Increased water hardness from industrial and municipal waste.
Persistent high toxicity levels impacting ecosystems.
Urgent need for continuous monitoring and pollution control.

 
Keywords: Temirnik River, chemical pollution, biological toxicity, historical data, anthropogenic impact
Escalating Antibiotic Resistance in Uremia Patients Demands Urgent Global Action
Authors: Hameed Ahmad Shandookh
Published: August 2024

Background: Uremia, a frequent complication of Chronic Kidney Disease (CKD), compromises immunity, increasing patients' susceptibility to bacterial infections. Multi-drug resistance (MDR) and extensively drug resistance (XDR) further exacerbate infection management challenges, particularly in regions with limited resources. Knowledge Gap: While bacterial resistance is well-documented globally, the prevalence and specific resistance patterns in uremia patients in Nasiriyah City remain underexplored. Aims: This study aimed to establish the prevalence and resistance profiles of MDR and XDR bacterial isolates among uremia patients in Nasiriyah City, with a focus on treatment implications and infection control strategies. Methods: A cross-sectional study was conducted at Al-Hussein Teaching Hospital from February 2023 to January 2024. One hundred samples from uremia patients were cultured and tested using the Kirby-Bauer disk diffusion method following CLSI guidelines. Results: The most frequently isolated bacteria were Escherichia coli (40%), Klebsiella pneumoniae (30%), Staphylococcus aureus (20%), and Pseudomonas aeruginosa (10%). High resistance rates were observed for Ampicillin (95%), Amoxicillin-Clavulanate (80%), and Ceftriaxone (75%), while resistance to Imipenem and Meropenem was lowest at 5% and 10%, respectively. Significant resistance patterns were noted across all tested antibiotics (P<0.05). Novelty: This study provides the first comprehensive analysis of MDR and XDR bacterial prevalence in uremia patients in Nasiriyah City, highlighting the critical need for targeted antibiotic stewardship. Implications: The findings underscore the urgency of implementing stringent infection control measures and developing alternative therapeutic strategies to combat the rising threat of antibiotic resistance in this vulnerable population. The efficacy of carbapenems, though still relatively preserved, necessitates cautious use to prevent further resistance development.
Highlights:
 

High resistance to common antibiotics in E. coli and K. pneumoniae.
Carbapenems remain effective, with low resistance rates.
Urgent need for antibiotic stewardship and alternative treatments.

 
Keywords: Uremia, Multi-drug resistance, Antibiotic susceptibility, Nasiriyah City, Infection control
Cladophora spp. Extracts Show Remarkable Antibacterial Potential Against Pseudomonas aeruginosa
Authors: Hussain Hussain Adnan , Mezal Ezat H. , Alashoor Ahmed. S.
Published: August 2024

Background: Bacterial resistance, influenced by genetic processes and adaptive strategies, necessitates the discovery of novel antibacterial agents, especially from natural sources. Specific Background: Pseudomonas aeruginosa, a notorious pathogen in urinary tract infections (UTIs), demonstrates considerable resistance to conventional therapies, necessitating alternative therapeutic approaches. Knowledge Gap: Research indicates that while natural sources like Cladophora spp. offer antibacterial agents, their effectiveness in combating P. aeruginosa resistant strains remains underexplored. Aims: This study aims to evaluate the antibacterial potential of Cladophora spp. algae extracts against Pseudomonas aeruginosa isolated from UTIs, utilizing solvent extraction, MIC determination, disc diffusion assays, and GC-MS analysis to identify bioactive compounds. Results: All extracts, including those prepared with water, ethanol, and hexane, demonstrated inhibitory effects on P. aeruginosa. The hexane extract exhibited the most significant activity, with a mean zone of inhibition of 13.0 ± 0.7 mm at a concentration of 50%. GC-MS analysis identified several bioactive compounds potentially responsible for these effects. Novelty: This study is among the first to investigate Cladophora spp. as a source of antibacterial agents specifically targeting P. aeruginosa, providing new insights into the potential of algae-based therapeutics. Implications: Cladophora spp. holds promise as a source of novel antibacterial compounds, with potential for multidrug-resistant infections treatments. Further research is needed for clinical application.
Highlights:
 

Hexane Extract: Most effective against Pseudomonas aeruginosa.
Novel Source: Cladophora spp. shows potential as antibacterial agent.
GC-MS Findings: Identified key bioactive compounds.

 
Keywords: Cladophora spp., Pseudomonas aeruginosa, antibacterial agents, natural extracts, GC-MS analysis
Identification Methods of Helicobacter Pylori Bacteria
Authors: Al-Mozan Hanaa Daaj Khalaf , Aziz Hussam Saadi
Published: August 2024

Background: Helicobacter pylori is a well-known carcinogenic pathogen associated with gastrointestinal diseases, often infecting individuals during childhood and persisting asymptomatically for years. Specific Background: The failure to diagnose H. pylori early can result in severe health consequences, making timely and accurate diagnosis critical to preventing its spread. Knowledge Gap: Diagnostic methods' effectiveness depends on patient age, economic status, and operator skill, with some tests being expensive and influenced by protocol adherence. Aims: The study evaluates the efficacy of various diagnostic methods for H. pylori, focusing on the accuracy, reliability, and practicality of invasive and non-invasive techniques. Results: Invasive methods like histology, endoscopy, culture, rapid urease test, and polymerase chain reaction (PCR) provide direct detection of the bacterium, while non-invasive methods such as the urea breath test, stool antigen assay, and serology offer indirect detection without requiring endoscopy. PCR, when conducted with appropriate primers and gene targets, remains the most accurate diagnostic tool. Novelty: The study emphasizes the superior diagnostic value of PCR due to its precision, despite challenges related to operator skill and procedural compliance. Implications: The study emphasizes the significance of selecting suitable diagnostic methods based on patient-specific factors and the need for skilled execution for accurate results in managing and treating H. pylori infections.
Highlights:
 

PCR Accuracy: Most reliable H. pylori test with correct primers and targets.
Operator Skill: Diagnosis depends on skilled execution and procedural adherence.
Test Selection: Choose based on patient age, economic status, and method availability.

 
Keywords: Helicobacter pylori, diagnosis, gastrointestinal diseases, PCR, invasive tests
Elevated Cadmium Drives Calcium Deficiency in Renal Failure Patients
Authors: Mohammed Mostafa Salim
Published: August 2024

Background: Renal failure (RF) is a significant health issue with various etiological factors, including environmental toxins. Specific Background: Cadmium (Cd), a known toxic heavy metal, has been implicated in renal damage, while calcium (Ca) levels may also be affected. Knowledge Gap: The relationship between Cadmium and Calcium levels in RF patients, despite the well-established link between heavy metals and renal impairment, remains underexplored. Aims: This study aimed to evaluate changes in blood serum Cd and Ca levels in RF patients and investigate their correlation. Methods: The study, conducted in Iraq from July 2023 to February 2024, involved 150 participants, including 100 RF patients and 50 healthy controls, and used Flame Atomic Absorption Spectroscopy for analysis. Results: The mean Cd level was significantly higher in RF patients (2.30 µg/L) compared to controls (1.44 µg/L, P < 0.05). Conversely, the mean Ca level in RF patients was significantly lower (36.06 mg/dL) compared to controls (51.85 mg/dL, P < 0.05). A significant negative correlation between Cd and Ca levels was found (P ≤ 0.001). Novelty: This study provides novel insights into the detrimental impact of elevated Cd levels on Ca status in RF patients. Implications: The study underscores the necessity of controlling Cd exposure and Ca levels in renal function (RF) management to mitigate its environmental impact on renal health.
Highlights:
 

Higher Cd Levels: Increased cadmium in RF patients.
Lower Ca Levels: Decreased calcium in RF patients.
Negative Correlation: Cadmium inversely affects calcium levels.

 
Keywords: Cadmium, Calcium, Renal Failure, Heavy Metals, Blood Serum
Honey Enhances Antibiotic Effectiveness Against Urinary Tract Infections
Authors: Fejer Lamyaa Gh. , Hameed Ghaidaa S. , Ali Mayssam Hussein Mohammed , Al-Hammood Orooba
Published: August 2024

Background: Urinary tract infections (UTIs) are prevalent across all ages and genders and pose significant treatment challenges, often requiring alternative therapeutic approaches due to increasing antibiotic resistance. Specific Background: The study examines the impact of antibiotics and honey on bacterial UTIs, revealing 17 cases, primarily caused by Staphylococcus aureus and Klebsiella pneumoniae. Knowledge Gap: The study evaluates the effectiveness of honey in combining antibiotics with anise and spring flower honey, focusing on its potential to enhance antimicrobial effects in UTIs. Results: Biochemical analysis and VITEK diagnostics revealed significant bacterial growth. Antibiotic susceptibility tests showed varied effectiveness, with spring flower honey enhancing the activity of nitrofurantoin (35%), trimethoprim (17.6%), trimethoprim-sulfamethoxazole (23.5%), tetracycline, and norfloxacin (35.2%). Anise honey also demonstrated notable synergistic effects, particularly with norfloxacin (47%) and tetracycline (41%). Novelty: This study highlights the potential of combining honey with antibiotics to combat UTIs, offering new insights into alternative treatment strategies and demonstrating significant synergy with specific antibiotics. Implications: The findings suggest that incorporating honey into UTI treatments could improve therapeutic outcomes and help mitigate the growing issue of antibiotic resistance. Further research is needed to identify active compounds in honey and optimize their use with antibiotics.
Highlights:
 

Enhanced Efficacy: Honey boosts antibiotic effectiveness against UTIs.
Resistance Solution: Combines honey to counteract antibiotic resistance.
Honey Variability: Different honeys show varied synergistic effects.

 
Keywords: Urinary Tract Infection, Antibiotics, Honey, Synergistic Effect, Antibiotic Resistance
Effect the Nanoparticles of Fe2O3 and CuO to Increasing the Activity of Sulfadiazine Against Multidrug Resistant Pseudomonas Aeruginosa
Authors: Saleem Ali Jaffar
Published: August 2024

General Background: Antibiotic resistance is a critical global health issue, and innovative approaches are needed to combat multidrug-resistant (MDR) bacteria. Specific Background: Nanotechnology has emerged as a promising strategy to enhance antibiotic efficacy and reduce resistance. Knowledge Gap: However, there is limited understanding of how metal oxide nanoparticles (NPs) like Fe2O3 and CuO can be utilized to improve the performance of antibiotics such as sulfadiazine. Aims: This study aimed to synthesize Fe2O3 and CuO nanoparticles, conjugate them with sulfadiazine, and evaluate their antibacterial efficacy against MDR Pseudomonas aeruginosa. Results: The nanoparticles were synthesized via chemical precipitation, with Fe2O3 and CuO having mean crystal sizes of 41.40 nm and 44.83 nm, respectively. When bound to sulfadiazine, the crystal sizes were 42.62 nm (Fe2O3) and 38.77 nm (CuO). The minimum inhibitory concentration (MIC) values for sulfadiazine-bound CuO and Fe2O3 NPs ranged from 16-32 μg/ml, significantly lower than the 64-128 μg/ml observed for standard sulfadiazine. Hemolysis assays confirmed the biocompatibility of these nanocomposites at tested concentrations. Novelty: The study reveals that Fe2O3 and CuO nanoparticles significantly enhance sulfadiazine's antibacterial activity against MDR P. aeruginosa, suggesting a potential method to bypass traditional resistance mechanisms. Implications: The study suggests that nanoparticle-conjugated antibiotics could be a promising solution for combating antibiotic resistance, potentially reducing its negative impact on public health.
Highlights:
 

Nanoparticles reduce sulfadiazine's MIC against MDR Pseudomonas aeruginosa.
Fe2O3 and CuO nanoparticles enhance antibiotic efficacy.
Hemolysis assays confirm nanocomposites' safety and biocompatibility.

 
Keywords: Nanotechnology, Antibiotic Resistance, Fe2O3 Nanoparticles, CuO Nanoparticles, MDR Pseudomonas aeruginosa
Pemberdayaan Masyarakat Dalam Upaya Pemanfaatan Sampah Plastik Untuk Meningkatkan Pendapatan (Studi Pada Pokda Di Desa Ujung Piring, Bangkalan)
Authors: Hananah Hananah , Anshori Mochammad Isa
Published: August 2024

The problem in this study is that the community's awareness and concern for handling waste by the people of Ujung Piring village is still very lacking, the habit of burning garbage is still increasing greatly, in the community at the tip of the plate in dealing with existing waste problems. Besides that, by burning garbage, it is felt by the community to be the fastest way to deal with this problem, but this is actually not the case. Research describes community empowerment in increasing community income with POKDA by collecting plastic waste from the community, depositors and from other management operations, turning the value of goods higher, these activities create job opportunities and additional income for the community. The method used in this research is descriptive qualitative method. Data collection was carried out through observation, in-depth interviews, and documentation. The results showed that the research activities explaining Community Empowerment in Plastic Waste Efforts to Increase Income at POKDA in Ujung Piring Village, Bangkalan were able to make significant changes to the environment.
Analysis of the Role of Training and Development in Improving Employee Performance at PT. Karya Muda Mandiri Bangkalan.
Authors: Henik Yulis , Wispandono Raden Mas Mochammad
Published: August 2024

PT. Karya Muda Mandiri Bangkalan is one of the companies engaged in providing heavy rental equipment, civil works, production of mineral water management, and steam washing which requires special skills. For that, the company has provided training for the employees, but it only runs for one year which causes frequent work accidents. The objectives of this study are to determine the role of training in improving employee performance at PT Karya Muda Mandiri Bangkalan and to determine the role of development in improving employee performance at PT Karya Muda Mandiri Bangkalan. This study is conducted by a qualitative method using purposive sampling method to select informants who are determined by several criteria. Technique of collecting data uses three ways by conducting in-depth interviews, observation and documentation. The results of this study are 1) After PT. Karya Muda Mandiri Bangkalan carries out training on employee performance, the company can improve the performance of its employees, can reduce the number of work accidents and can make the company better. 2) The role of development at PT. Karya Muda Mandiri Bangkalan is that the employee performance is getting better. From the training, employees gain new knowledge and new experiences so that their performance can be maximized and have a positive impact on the company and also for consumers. The conclusions of this study are 1) Performance training for employees of PT. Karya Muda Mandiri Bangkalan is getting better than before in heavy equipment operation, heavy equipment maintenance, mineral water management and mineral water management machine maintenance. 2) Development of employee performance at PT. Karya Muda Mandiri Bangkalan is getting better. When employees are included in the training, the development of employee knowledge, skills and behaviors that bring changes to the company can be seen. Employees can further increase the service users and the employee performance can also be maximized.
Pengaruh Electronic Word Of Mouth (E-WOM) Terhadap Minat Berkunjung Melalui Citra Destinasi Pada Wisata Taman Rekreasi Kota Bangkalan
Authors: Wahyuni Sri , Wantara Pribanus
Published: August 2024

The development of the use of internet and social media is an oppurtunity for a tourist destination to increase the visitors. Likewise with TRK tour which is said still have minimal visitors, therefore there is a need information containing a special specification of TRK to triggers visit intention to make visit such as the destination image that is through EWOM. The purpose of this research was to find out how much influence EWOM has on visiting intention through destination image on Taman Rekreasi Kota in Bangkalan. This research using quantitative research with survey method via questionaire. The data analysis technique used to prove the hypothesis was compiled using Path Analysis and using the Sobel Test. The results of this research show that (1) EWOM has a direct, significant effect on visisting intentions; (2) EWOM has a direct effect on destination image; (3) The destination image has no effect on visiting interest and is not significant; (4) EWOM has limited indirect effect on visiting intention through the destination image, the destination image is able to mediate the effect between the Electronic Word Of Mouth on visiting intention. The researcher can conclude that the use of Electronic Word Of Mouth can influence the visiting intention and destination image is able to mediate it, but the mediating variable does not have much influence on the visiting intention.
Analisis Perbandingan Volume Perdagangan Saham, Abnormal Return dan Frekuensi Saham Perusahaan Sektor Energi Yang Terdaftar di Bursa Efek Indonesia Sebelum dan Sesudah Pelarangan Ekspor Batubara untuk Ketahanan Energi Dalam Negeri 2022
Authors: Habibillah R Apriyanto , Nugroho Prasetyo
Published: August 2024

This study aims to find out and compare the trading volume activity, abnormal return  and frequency of trading shares of energy companies before and after the announcement of the ban on export coal  for Domestic Market Obligation in Indonesia.The population in this study are companies that are included in the Energy Sector listed at IDX. The samples in this study used purposive sampling, where only 17 companies met the criteria. In this  study, the data used is 14 days before and after the announcement of the ban on export coal  for Domestic Market Obligation in Indonesia. The hypothesis test used is Wilcoxon Signed Rank Test. The result showed that: 1) there is a significant  differences in the trading volume and frequency trading share of sample  companies before and after the ban on export for Domestic Market Obligation, 2) there is no significant difference in the abnormal return of sample companies before and after the ban on export for Domestic Market Obligation.
Analisis Harga Diri, Efikasi Diri, dan Lokus Kendali pada Pokdarwis Putra Lon Malang
Authors: Faisol Achmad , Irawati S. Anugrahini
Published: August 2024

This study aimed to find out the description of Self Esteem, Self Efficacy, and Locus of Control at Pokdarwis (tourism awareness group) Putra Lon Malang, the organization that manages Lon Malang Beach. This research was a qualitative study with descriptive approach. The determination of informants was carried out using a purposive sampling technique and the data collection procedures employed observations, interviews, and documentation. Data analysis techniques used data reduction, data presentation, and conclusion. In addition. To ensure the validity of the data, the researcher employed credibility, transferability, dependability, and confirmability tests through triangulation (combination). The results showed that the organization managing the Lon Malang Beach tourist attraction, in this case, the Pokdarwis Putra Lon Malang, had a high level of self esteem, they are aware of the power or ability to control visitor activities to direct, reprimand, and even give strict punishment to visitors who break the rules with confidence. Regarding the self-efficacy of the Pokdarwis Putra Lon Malang members, they are confident in their ability to complete every task that is their responsibility as the organization that manages the tourist attraction. Regarding locus of control, they tend to believe that everything that happens in life is under self-control.
Pengaruh Harga, Kualitas Produk dan Citra Merek Terhadap Keputusan Pembelian Rizqy Bakery Bangkalan (Studi Pada Konsumen Rizqy Bakery Bangkalan)
Authors: Alisiyah Hoomzah Nur , Kurriwati Nirma
Published: August 2024

The purpose of this study was to determine the effect of price, product quality and brand image on purchasing decisions of Rizky Bakery Bangkalan, either partially or simultaneously on purchasing decisions. This research uses quantitative methods. The data analysis technique used is multiple linear regression analysis. The sampling technique used the non-probability sampling technique with the sampling method using the purposive sampling method which obtained as many as 80 respondents. The population used in this study are consumers who have purchased Rizky Bakery Bangkalan products. The results of this study indicate that price, product quality and brand image have a partial effect on purchasing decisions. Price, product quality and brand image have a simultaneous influence on purchasing decisions.
Pengaruh Citra Merek, Kualitas Produk, dan Harga Terhadap Keputusan Pembelian produk Cok Ko Tengok (CKT) Pada Masyarakat Kota Pematang Siantar
Authors: Simanjuntak Clinderton Alfrado , Purnomo Hadi
Published: August 2024

The purpose of this study determines variables of brand image, product quality and price have a partial and simultaneous influence on the purchase decision of Cok Ko Tengok products in the people of Pematang Siantar city.This study used a quantitative approach and the sampling used a non-probability sampling method with 96 sample, analyzed using regression analysis and the analysis tool, SPSS. Based on the test results on data that has been collected through questionnaires distributed. The results of the first hypothesis were obtained that the brand image variable had a significant and simultaneous effect on purchasing decisions, product quality was not significant on purchasing decisions but had a simultaneous effect, price had a significant and simultaneous effect.
Pengaruh Penggunaan Financial Technology (Fintech) Payment dan Uang Saku terhadap perilaku keuangan mahasiswa S1 Manajemen Fakultas Ekonomi dan Bisnis Angkatan 2019 Universitas Trunojoyo Madura
Authors: Hamro Najmatul , Susandini Aprilina
Published: August 2024

This study aims to determine the effect of using financial technology (Fintech) Payments and Pocket Money on the financial behavior of S1 Management students at the Faculty of Economics and Business Class of 2019, University of Trunojoyo Madura. The population used in this study was 282 students with purposive sampling method and 165 students were selected as samples in this study. The method used is descriptive quantitative. The data used in the study were obtained by distributing questionnaires to 2019 Batch of Management students at the Faculty of Economics and Business University of Trunojoyo Madura. The results of this study indicate that financial technology (fintech) Payment has a positive and significant effect on the financial behavior of S1 Management students at the Faculty of Economics and Business Class of 2019 Trunojoyo University Madura, Pocket Money has a positive and significant effect on the financial behavior of S1 Management students at the Faculty of Economics and Business Class of 2019 University Trunojoyo Madura and financial technology (fintech Payment and Pocket Money) have a positive and significant effect on the financial behavior of S1 Management students at the Faculty of Economics and Business Class of 2019, University of Trunojoyo Madura.
Pengaruh Kesadaran Lingkungan, Sikap Konumen dan Harga Terhadap Keputusan Pembelian Produk Ramah Lingkungan Botol Tumbler (Studi Pada Mahasiswa S1 Fakultas Ekonomi Dan Bisnis Universitas Trunojoyo Madura)
Authors: Safitri Dina , Setiyarini Triana
Published: August 2024

This study aims to determine the effect of environmental awareness, consumer attitudes and prices towards and prices on purchasing decisions for eco-friendly tumbler bottles. This study used a quantitative approach with data collection methods distributing questionnaires to students of the Faculty of Economics and Business, University of Madura. The sample 97 respondent. Data analysis techniques were performed using descriptive statistical analysis. Based on the results of data analysis and discussion of prices, the t value of the environmental awareness variable with sig. 0.515 where 0.05 does not have a significant influence on the purchasing decisions. The t value of consumer attitude variable with sig. 0.003 where 0.05, consumer attitudes have a significant influence on purchasing decisions. The value of the price variable t value with sig. 0.000 where 0.05, the price has a significant influence on the purchase decision. Simultaneously, Environmental Awareness, Consumer Attitude and Price have a significant effect on Purchase Decision, with an F-count of with a significance value of 0.000 0.05.
Pengelolaan Keuangan melalui Pengetahuan Keuangan, Sikap Keuangan, dan Gaya Hidup
Authors: Safitri Anni , Amaniyah Evaliati
Published: August 2024

The purpose of this study was to determine the influence of financial knowledge, financial attitudes and lifestyle on financial management among unmarried workers in Bojonegoro Regency. The selected population is all unmarried workers in Bojonegoro Regency. Samples are selected using the purposive sampling method and 96 respondents were selected. The type of study is quantitative. The data used in the study was obtained by distributing questionnaires. Data analysis techniques consist of descriptive statistics, testing research instrument requirements, classical assumption testing, multiple linear regression analysis, and hypothesis testing using SPSS 26 tools. The result of this study show that (1) Knowledge variables and lifestyle variables partially has an effect on financial management among unmarried workers in Bojonegoro Regency (2) The financial attitude variable partially has no effect on financial management among unmarried workers in Bojonegoro Regency (3) The variables of financial knowledge, financial attitude and lifestyle simultaneously have an effect on financial management
Motivasi Kerja sebagai Pemediasi dari Disiplin Kerja Dan Lingkungan Kerja Terhadap Kinerja Pegawai Perusahaan Daerah Air Minum (Pdam) Kota Bangkalan
Authors: Rahaditya Reza Rifqy , Aulia Safrizal Helmi Buyung
Published: August 2024

This study discusses the problems found at one of the government institutions, namely the PDAM Bangkalan, East Java. This study aims at determining the effect of work discipline and work environment on employee performance with work motivation as an intervening variable. This study employed a quantitative approach, using path analysis. A total of 51 respondents were involved in this study. The purpose of this study was to examine the effect of work discipline and work environment on employee performance with work motivation as an intervening variable. Based on the results of the analysis, it shows that 1) Work Discipline Variable has a positive and significant effect on Employee Performance. This is shown by the results of the calculation of the t-test, the t- count value is 2.377, and the t-table value is 2.01174 with a significance of 0.022 0.05. 2) Work Environment Variables have a positive and significant effect on Employee Performance. This is shown by the results of the calculation of the t-test, which comprises the t-count value of 2.324 and the t-table value of 2.01174 with a significance value of 0.024 0.05. 3) Work motivation variable has a positive and significant effect on employee performance. This is shown by the results of the calculation of the t-test, the t- count value of 2.212, and the t-table value of 2.01174 with a significance value of 0.032 0.05. 4) The Variable of Work Discipline has a positive and significant effect on Work Motivation. This is shown by the results of the calculation of the t-test, the tcount value of 2.907, and the t-table value of 2.01063 with a significance value of 0.006 0.05. 5) Work Environment Variable has a positive and significant effect on Work Motivation. This is shown by the results of the calculation of the t-test, the tcount value of 3.040, and the t-table value of 2.01063 with a significance value of 0.004 0.05. 6) Work Discipline Variable has a positive and significant effect on Employee Performance through Work Motivation. This is shown by the results of path analysis calculations with a path coefficient of 0.394 with a t-count of 2.619847 ttable of 2.01174. 7) Work Environment Variable has a positive and significant effect on Employee Performance through Work Motivation. This is shown by the results of path analysis calculations with a path coefficient of 0.479 with a t-count of 1.778234 a t-table of 2.01063.
Keputusan Pembelian melalui Live Streaming E-Commerce Shopee, Online Customer Review, dan Free Gift (Studi Kasus pada Pelanggan MS Glow by Mirza)
Authors: Monica Sevi , Jannah Miftahul
Published: August 2024

This research aims to determine the influence of Shopee e-commerce live streaming, online customer reviews, and free gifts on purchasing decisions for MS Glow by Mirza. The research method uses quantitative methods. The data used are primary and secondary data. Data was obtained by distributing questionnaires to a sample of 100 respondents. This research uses a purposive sampling method and the analytical tool used is multiple linear regression with the help of the SPSS 29 program. Partial test results show that live streaming has a significant influence on purchasing decisions, online customer reviews have no significant influence on purchasing decisions, and free gifts have no significant influence on purchasing decisions. For simultaneous tests, it shows that live streaming, online customer reviews, and free gifts have a significant influence on purchasing decisions. The coefficient of determination value is 0.665, meaning that the regression model obtained is able to explain that the variables live streaming, online customer reviews, and free gifts can influence purchasing decisions for MS Glow by Mirza products by 66.5%. Meanwhile, the remaining 33.5% is influenced by other variables not explained in this research.
PENGARUH KEPEMIMPINAN KARISMATIK KIYAI DAN BUDAYA ORGANISASI DALAM PEMBENTUKAN KARAKTER SANTRI DI PONDOK PESANTREN AL-AMIN PARENDUAN KABUPATEN SUMENEP
Authors: Rohim Robi , Wildan Muhammad Alkirom
Published: August 2024

The aim of the research is to determine the factors that can influence the character of students. The population in this study was 8,086 students at the Al-Amien Perenduen Islamic Boarding School, Sumenep Regency. The sampling technique used was simple random sampling, so that a sample of 100 students was obtained. This research is quantitative research using the variabels kiyai leadership style (X1) and organizational culture (X2) as independen variabels. Meanwhile, the student character variabel (Y) is the dependent variabel. This research uses primary data by distributing questionnaires to respondents. The primary data obtained was then analyzed using SPSS. The data analysis techniques used include data quality testing, classical assumption testing and hypothesis testing using multiple linear regression analysis. The results of the research show that the kiyai's leadership style and organizational culture on the character of the students at the Al-Amien Perenduen Islamic Boarding School, Sumenep Regency, have a very strong or very high correlation. The kiyai's leadership style and organizational culture have an influence of 65.61% on the character formation of students at the Al-Amien Perenduen Islamic Boarding School, Sumenep Regency.
Kewajiban Penanaman Pohon Sebagai Syarat Penerbitan Rekomendasi Pengantar Nikah dalam Peraturan Bupati Magetan Nomor 11 Tahun 2020 Tentang Gerakan Wajib Menanam Pohon
Authors: Safudin Endrik , Khasanah Uswatul
Published: August 2024

Peraturan Bupati Magetan Nomor 11 Tahun 2020 tentang Kewajiban Menanam pohon memiliki maksud yang mulia yaitu mendorong peran masyarakat dalam pengelollan dan kelestarian hidup. Kewajiban penanaman pohon tersebut salah satunya dibebankan kepada calon pengantin baik pria maupun wanita. apabila tidak melaksanakan kewajiban tersebut maka tidak diterbitkan rekomendasi pengantar nikah (NA) atau bentuk lainnya dari kepala desa/lurah. Kewajiban penanaman pohon bagi calon pengantin tersebut dapat dikatakan sebagai suatu bentuk penambahan persyaratan pernikahan yang tidak pernah diatur oleh peraturan yang lebih tinggi yang mengatur tentang persyaratan dan rukun pernikahan. Oleh karena itu menarik untuk dianalisis tentang keteraturan norma terhadap Peraturan Bupati Magetan Nomor 11 Tahun 2020 tentang Kewajiban Menanam Pohon dengan peraturan yang lebih tinggi. dengan menggunakan metode penelitian normative dan pendekatan perundang-undangan (legal approach), penelitian ini fokus pada keteraturan norma sebagai wujud adanya tertib substansi pada suatu peraturan perundang-undangan. hasil penelitian ini menunjukkan bahwa Peraturan Bupati Magetan Nomor 11 Tahun 2020 tentang Kewajiban Menanam Pohon khususnya bagi calon pengantin telah mengandung ketidaktertiban substansi dengan peraturan yang lebih tinggi yang mengatur tentang pernikahan. sehingga, peraturan bupati tersebut akan sulit dioperasionalkan dimasyarakat terlepas dari tujuan mulia dilahirnnya peraturan tersebut.
Keterlibatan Hakim Perempuan Sebagai Pekerja Publik Sekaligus Istri Dalam Mencipatakan Keluarga Yang Harmonis Perspektif Hukum Islam
Authors: Gardeni Alma Sari , Rofiah Khusniati
Published: August 2024

A female judge has a dual role when the judge is married. It's not just work that needs to be done. However, work as a wife and housewife must also be considered. A female judge certainly has high consequences for work. Not only is he responsible for his work, a judge must of course be ready to be transferred to various court areas throughout Indonesia. Moreover, a female judge, who is basically a woman, also plays an important role in the family, especially. For example, serving your husband and having to educate and give love to your children. The focus of the research is related to the role of female judges in earning a living and in creating family harmony when they have to be transferred to areas far from their families. This thesis is a qualitative research type of field research with a normative approach. Meanwhile, technical data collection involves conducting interviews and documentation. The analysis used in this research is descriptive analysis with an inductive method.
Comparing the effect of calcium citrate supplement with normal calcium diet on metabolic risk factors in recurrent calcium stone formers with idiopathic hyperoxaluria: A randomized clinical trial
Authors: Taheri Maryam , Tavasoli Sanaz , Jalali Saba , Borumandnia Nasrin , Basiri A
Published: August 2024

Background
Calcium supplementation is only recommended to treat enteric hyperoxaluria, and its effect on idiopathic hyperoxaluria has not been thoroughly assessed. In this study, we compare the effect of calcium citrate supplementation with adequate dietary calcium intake on 24-hour urine (24-U) oxalate, calcium, and calcium oxalate supersaturation index (Ca Ox SS).
Subjects:
In a parallel-group controlled randomized clinical trial, 72 recurrent calcium stone formers with idiopathic hyperoxaluria were recruited from a tertiary stone prevention clinic in 2019–2020. 24-hour urine analyses and filling the 24-hour food recall were done at baseline and after eight weeks of intervention. Finally, 44 patients completed the study protocol. The participants were randomly assigned to receive adequate calcium through diet or taking 800 mg calcium citrate (in two divided doses with lunch and dinner) with a limited intake of dairy products. The study’s outcome was the change of 24-U Ox, Ca, and CaOx SS index after intervention.
Results
Findings showed that both interventions significantly reduced 24-U Ox (B Time effect: -10.06, 95% CI: -13.70, -6.42; p < 0.001) and CaOx SS index (B Time effect: -2.54, 95% CI: -4.06, -1.02; p = 0.001). After adjusting the effect of potential confounders through a Random-effects ML regression, the reduction of 24-U Ox remained significant. There was no significant increase in 24-U Ca in both intervention groups (p = 0.269).
Conclusions
Calcium citrate supplementation effectively reduces 24-U Ox levels comparably to adequate dietary calcium intake, without significantly raising 24-U Ca levels, offering a viable management option for calcium stone formers with idiopathic hyperoxaluria.
Comparison and standardization of traditional siddha medicine pavala parpam
Authors: L Keerthana - , V Sharulatha - , P Pavithra -
Published: August 2024

Bronchial asthma is the condition in which persons airways become inflamed, swell and narrow and produce extra mucus and it makes breathing difficult. There are number of allopathic and ayurvedic drugs available to treat bronchial asthma, but those drugs cause severe side effects to the patients. Hence majority of the people prefer Siddha drug to treat bronchial asthma due to less side effects. Siddha medicine is an ancient system of medicine that aims at spiritual and physical perfection. According to Siddha pharmaceutical principles, when pavalam (red coral) is combined with herbal juices and purified it obtains high range of medicinal value. Pavala parpam is a traditional herbo-mineral formulation. In present study two samples of pavala parpam, one containing Ziziphus mauritiana herbal juice and other containing Heliotropium indicum herbal juice were purchased. And the standardization of this drug samples was done based on organoleptic, physico-chemical, phytochemical analysis and morphological analysis. When comparing both drugs, the result showed only slight changes in organoleptic and physicochemical analysis and major changes showed in phytochemical analysis. The FE-SEM and XRD results showed that the drug have better absorption capacity due to presence of micro particles in both the samples.
Population genetic structure of cotton pink bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae) from India
Authors: nagamandla ramyasri , Pushpavalli SN , T Uma Maheswari
Published: August 2024

Background Pink boll worm, Pectinophora gossypiella became serious pest on BG II cotton hybrids globally causing huge economic losses in cotton even during later stages of crop growth. Understanding the genetic background and diversity of insect pests can aid in understanding their evolution in changing environments, hence aiding in effecting their management in an agricultural ecosystem.
Results In the present investigation, the population genetic structure, distribution, and genetic diversity of P.gossypiella in cotton growing zones of India using partial mitochondrial DNA cytochrome oxidase-I (COI) gene was addressed. Results revealed a total of 9 haplotypes (17.64%) identified from 51 individual sequences distributed in 16 populations belonging to different cotton growing zones of India. Diversity analysis of COI sequences revealed low genetic diversity (0.000 to 0.01066), high haplotype diversity (0.800), low nucleotide diversity (0.002), negative Tajima D (-0.670) values and high gene flow.
Conclusion This data on population genetics indicate populations of pink bollworm are genetically similar and in Median Joining network Hap5 occupied central position and connected by low frequency haplotypes which are formed due to one or two point mutations indicating recent population expansion from limited number of founders due to post-Pleistocene warming and with the domestication range of hosts. Neutrality tests also support low frequency polymorphisms in the population consistent with the recent population expansion after bottleneck or selection sweep.
Fatal outcomes following onasemnogene abeparvovec in advanced-stage spinal muscular atrophy
Authors: sanmaneechai oranee , Pongsakornkullachart Peerada , Kulsirichawaroj Pimchanok , Kongkasuwan Ratcharin , Tovichien Prakarn , Jitwongwai Settapong , Kanjanauthai Supaluck , Preeprem Nutnicha , Limpaninlachart Sivaporn , Sermpon Nisasri
Published: August 2024

Objective
Supported by encouraging trial outcomes, onasemnogene abeparvovec (OA) was authorized for treating spinal muscular atrophy (SMA) in children under 2 years of age. Nevertheless, the efficacy of OA in advanced SMA patients remains underexplored. This investigation assessed the clinical effectiveness and adverse effects of OA in a patient cohort including those with advanced SMA, and compared these outcomes to historical survival data for SMA type 1 patients in Thailand.
Methods
We conducted an observational cohort study at Siriraj Hospital, Thailand, from May 2019 to April 2022. The study enrolled eight SMA patients receiving OA therapy. We monitored safety through laboratory tests and clinical evaluations. Patient outcomes, such as motor scores, motor milestones, and survival status, were analyzed.
Results
The cohort comprised five SMA type 1 patients treated at median age of 16.7 months (6.5–24.9 months) and three SMA type 2 patients treated at median age of 20.3 months (19–31.5 months). Before receiving OA, all type 1 patients needed invasive ventilation and nutritional support by feeding tubes. Posttreatment, these patients did not achieve new motor milestones, their survival rates remained static, and each patient experienced severe adverse events, including fatalities. Conversely, type 2 patients exhibited improved motor scores without experiencing serious adverse events.
Interpretation:
This real-world evaluation revealed that OA did not significantly improve outcomes or survival rates among advanced SMA type 1 patients, with all such cases resulting in mortality. These findings suggest the need for additional caution and revised guidelines when administering OA to this subgroup.
Randomized control trial on the effects of a home-based computer- adaptive cognitive training for patients with vascular cognitive impairment
Authors: Soni Amit Kumar , Kumar Mohit , Kothari Saroj
Published: August 2024

Vascular cognitive impairment (VCI) encompasses a range of cognitive deficits attributed to cerebrovascular disease, varying from minor cognitive disruptions to dementia. Innovative technological approaches, such as computerized cognitive retraining, offer promising strategies for mitigating the cognitive challenges faced by individuals with VCI. Despite their potential, the impact of these interventions on neuropsychological function and daily living capabilities has poor outcomes. In this randomized controlled trial (RCT), the effectiveness of a 4-week, remotely-delivered, multi-domain, computer-adaptive cognitive retraining (CACT) was assessed in a cohort of 62 VCI patients. Employing an active control research design, participants were randomly allocated to either an Experimental group, which underwent the CACT program tailored to individual performance levels, or a control group that received standard care. The evaluation focused on neuropsychological functions such as attention, memory, and executive processes, alongside daily living skills. Results indicated that participants in the CACT group exhibited notable improvements in several cognitive areas, including processing speed, category fluency, and visual confrontation naming, when compared to the control group. Nonetheless, enhancements in functional abilities, encompassing basic and instrumental activities of daily living (ADL), were minimal, with no significant changes reported post-intervention. This study proposes that extended periods of adaptive cognitive training might lead to more substantial improvements following CACT.