bluuebunny/crossref_metadata_2025 huggingface dataset:
Interaction Mechanism between Inter-Organizational Relationship Cognition and Engineering Project Value Added from the Perspective of Dynamic Impact
Authors: Xu Mengyu , Liu Xun , Bian Zhen , Wang Yufan
Published: September 2024

Projects involve inter-organizational relationship cognition, which is central to collaborative engineering project value added. Interest in value added in the project lifecycle is mounting and gaining increasing attention in the research literature. However, little is known about how inter-organizational relationship cognition facilitates value added and how such cognition pushes a project toward higher end-states of value. The existing literature mainly analyzes and studies value added on functional analysis and cost control. There are predominantly static analyses of the factors that influence value added in studies. The guiding role of value added has not been adequately explored in the studies on the influencing factors of value added. Utilizing a combination of Structural Equation Modeling (SEM) and Fuzzy Cognitive Maps (FCMs), this study addresses how inter-organizational relationship cognition influences engineering project value added, identifying complex structures of interaction and cognition dynamics. Results indicate that: (1) A hybrid SEM–FCM method can be able to model dynamic interactions between inter-organizational relationship cognition and value added; (2) trust and shared vision have positive effects on in-role behavior and extra-role behavior. Shared vision has a negative effect on opportunistic behavior. In-role behavior and extra-role behavior have a positive impact on value added, while opportunistic behavior has a negative impact. Organizational behavior is an important mediating variable to explain the interaction between inter-organizational relationship cognitions and value added. This hybrid method explores the potential mechanisms of inter-organizational relationship cognition on project value added from novel perspectives on construction project management practices, proposing practical advice for further project management.
HIV Vaccine Development at a Crossroads: New B and T Cell Approaches
Authors: Govindan Ramesh , Stephenson Kathryn E.
Published: September 2024

Despite rigorous scientific efforts over the forty years since the onset of the global HIV pandemic, a safe and effective HIV-1 vaccine remains elusive. The challenges of HIV vaccine development have proven immense, in large part due to the tremendous sequence diversity of HIV and its ability to escape from antiviral adaptive immune responses. In recent years, several phase 3 efficacy trials have been conducted, testing a similar hypothesis, e.g., that non-neutralizing antibodies and classical cellular immune responses could prevent HIV-1 acquisition. These studies were not successful. As a result, the field has now pivoted to bold novel approaches, including sequential immunization strategies to drive the generation of broadly neutralizing antibodies and human CMV-vectored vaccines to elicit MHC-E-restricted CD8+ T cell responses. Many of these vaccine candidates are now in phase 1 trials, with early promising results.
Assessing and Optimizing Ecological Flow Rates for the Habitat of Zacco platypus in the Tan River
Authors: Noh Yeonjung , Kim Seongjoon , Hong Eunmi
Published: September 2024

As rivers face growing environmental challenges due to climate change and the construction of artificial structures, it is essential that we improve river ecosystems to maintain their ecological functions and preserve the health of aquatic habitats. The aim of this study was to assess the aquatic ecosystem health of the lower reaches of the Tan River. We employed the Physical Habitat Simulation System and Hydrologic Engineering Center’s River Analysis System to calculate the ecological flow rate based on the weighted usable area (WUA) of Zacco platypus, which is a representative fish species in the Tan River, and the flow rate relationship curves. By analyzing the flow rates in the Tan River across different seasons from 2012 to 2021, we determined that the seasonal optimal ecological flow rate was 10.21–10.27 m3/s. Meanwhile, the WUAs for spring, summer, and autumn and winter were 90–100%, 95–100%, and 75–100%, respectively. Despite meeting the ecological flow criteria for summer, fall, and winter over 50% of the time, spring fell short at 41%; hence, the Tan River flow rates should be secured particularly in spring. This study highlights the urgency of addressing seasonal variations to ensure the overall health of the Tan River ecosystem.
Karst Hydrological Connections of Lakes and Neoproterozoic Hydrogeological System between the Years 1985–2020, Lagoa Santa—Minas Gerais, Brazil
Authors: Pacheco Neto Wallace , de Paula Rodrigo , Galvão Paulo
Published: September 2024

This study focuses on a complex Brazilian Neoproterozoic karst (hydro)geological and geomorphological area, consisting of metapelitic–carbonate sedimentary rocks of ~740–590 Ma, forming the largest carbonate sequence in the country. At the center of the area lies the Lagoa Santa Karst Environmental Protection Area (LSKEPA), located near the Minas Gerais’ state capital, Belo Horizonte, and presents a series of lakes associated with the large fluvial system of the Velhas river under the influence, locally, of carbonate rocks. The hydrodynamics of carbonate lakes remain enigmatic, and various factors can influence the behavior of these water bodies. This work analyzed the hydrological behavior of 129 lakes within the LSKEPA to understand potential connections with the main karst aquifer, karst-fissure aquifer, and porous aquifer, as well as their evolution patterns in the physical environment. Pluviometric surveys and satellite image analysis were conducted from 1984 to 2020 to observe how the lakes’ shorelines behaved in response to meteorological variations. The temporal assessment for understanding landscape evolution proves to be an effective tool and provides important information about the interaction between groundwater and surface water. The 129 lakes were grouped into eight classes representing the hydrological connection patterns with the aquifers in the region, with classes defined for perennial lakes: (1) constantly connected, (2) seasonally disconnected, and (3) disconnected; for intermittent lakes: (4) disconnected during the analyzed time interval, (5) seasonally connected, (6) disconnected, (7) extremely disconnected, and (8) intermittent lakes that connected and stopped drying up. The patterns observed in the variation of lakes’ shorelines under the influence of different pluviometric moments showed a positive correlation, especially in dry periods, where these water bodies may be functioning as recharge or discharge zones of the karst aquifer. These inputs and outputs are conditioned to the well-developed karst tertiary porosity, where water flow in the epikarst moves according to the direction of enlarged karstified fractures, rock foliation planes, and lithological contacts. Other factors may condition the hydrological behavior of the lakes, such as rates of evapotranspiration, intensity of rainfall during rainy periods, and excessive exploitation of water.
Tourist route in memory of the poet Rasul Gamzatov
Authors:   Lugansk State Pedagogical University, Lugansk, Murtuzaliev S. I.
Published: September 2024

The potential of the Republic of Dagestan in terms of tourism development is enormous. The article talks about the creation of a new tourist route associated with the work of the great poet Rasul Gamzatov.
THE USE OF A NEW BIOGENIC FEED ADDITIVE IN THE CULTIVATION OF BULLS
Authors: ГОРЛОВ И.Ф. , КАРПЕНКО Е.В. , ГРИШИН В.С. , НАТЫРОВ А.К. , МОРОЗ Н.Н. , УБУШАЕВ Б.С. , БАДМАЕВА К.Е. , ЭДГЕЕВ В.У.
Published: September 2024

Изучено влияние водного экстракта полыни горькой в составе рациона бычков калмыцкой породы после их отбивки в 6-месячном возрасте. Для опыта было сформировано по принципу аналогов 4 группы молодняка по 10 голов с живой массой особей 163,2—165,7 кг: контрольная и 3 опытных. Животные I, II, III опытных групп кроме основного рациона получали биогенную кормовую добавку в дозах 5, 15 и 25 мл на 1 голову в сутки соответственно. Установлено положительное влияние кормовой добавки, изготовленной на основе полыни, с целью повышения уровня бактерицидной активности у молодняка крупного рогатого скота. У особей II опытной группы этот показатель составил 74,23%, что на 5,91 п.п. выше, чем в контрольной группе. Фагоцитарная активность сыворотки крови у этих животных была выше на 11,72 п.п. по сравнению с контролем. Бычки, получавшие биогенную кормовую добавку в количестве 15 мл на 1 голову, демонстрировали наибольшую интенсивность роста. Применение разработанной кормовой добавки позволило повысить убойные качества подопытного молодняка. Установлено, что убойная масса бычков контрольной группы была ниже, чем у их сверстников из I, II и III опытных групп, на 7,4 (3,75%, P≤0,05), 18,4 (9,34%, Р≤0,001) и 4,3 кг (2,18%) соответственно. Убойный выход колебался по группам от 54,9 до 56,7%. Применение биогенной кормовой добавки из полыни в дозе 15 мл на 1 голову позволило повысить показатели неспецифической резистентности и продуктивные качества молодняка.

The effect of wormwood aqueous extract in the diet of Kalmyk bull calves after their culling at the age of 6 months was studied. For the experiment, 4 groups of young animals of 10 heads with a live weight of 163.2—165.7 kg were formed according to the principle of analogues: a control and 3 experimental groups. Animals of the I, II, III experimental groups, in addition to the basic diet, received a biogenic feed additive in doses of 5, 15 and 25 ml per a head per day, respectively. The positive effect of feed with wormwood extract has been revealed based on young cattle bactericidal activity level. This indicator in II experimental group was 74.23%, which is 5.91 percentage points higher than in the control group. Blood serum phagocytic activity in this case was 11.72 percentage points higher compared to control group. The bulls receiving the biogenic feed additive in amount of 15 ml per a head showed the highest growth rate. The use of the developed feed additive made it possible to increase experimental young animals slaughter qualities. It was found that slaughter weight of the control group bulls was lower than that of their peers from I, II and III experimental groups by 7.4 (3.75%, P≤0.05), 18.4 (9.34%, P≤0.001) and 4.3 kg (2.18%), respectively. Overall carcass yield ranged in groups from 54.9 to 56.7%. The use of the biogenic feed additive from wormwood in a dose of 15 ml per a head allowed increasing nonspecific resistance and productive qualities indicators of young animals.
El modelado para el desarrollo de la motricidad fina
Authors: Ramírez Aimacaña Anahí Gabriela , Sanguil Analuisa Shirley Lizbeth
Published: September 2024

El modelado es una técnica valiosa que involucra la creación de figuras y formas utilizando materiales como arcilla o plastilina, siendo un método que ha demostrado que tiene un impacto significativo en el desarrollo de la motricidad fina en niños de cero a los cinco años de edad. Por tanto, el objetivo fue evaluar el uso del manual “El reino de las fantasías” en el desarrollo de la motricidad fina en niños de educación inicial mediante la aplicación de la técnica del modelado. Por lo tanto, el enfoque de la propuesta sigue una metodología constructivista, la misma que forma parte de la estructuración de las actividades lúdicas, que a través de la lista de cotejo permitieron obtener resultados favorables, evidenciando un perfeccionamiento en el desarrollo de sus destrezas manipulables, su coordinación ojo-mano y sus actitudes creativas o expresivas. Finalmente, la técnica del modelado, implementada a través del manual "El reino de las fantasías," es altamente efectiva en la mejora de las habilidades motoras finas en niños de educación inicial.
EVALUASI PENGGUNAAN APLIKASI SISKEUDES DALAM UPAYA PENINGKATAN KUALITAS AKUNTABILITAS KEUANGAN DESA
Authors: Rahma Rika , Abdillah Muhammad Abdian
Published: September 2024

The method used is a qualitative research method. This study aims to determine how the evolution of the use of the Village Financial System Application in Mattunru- Tunrue Village and the quality of village financial accountability after the application of the Village Financial System Application. Data collection techniques used are observation, interviews, documentation, literature study, internet searching. This study uses the term informant, namely village employees who understand and are directly involved in the process of using the Village Financial System Application and the people of Mattunru- Tunrue Village who feel the benefits of implementing the application. The data analysis techniques used were data reduction, data presentation, and data conclusion. From the results of the evolution of the use of the village financial system application in Mattunru- Tunrue Village, it is known that Mattunru- Tunrue Village regularly updates the village financial system application version every year, this is done so that the village can use existing and improved features or the latest features of the application to support the creation financial reports. Then for the quality of financial accountability in Mattunru- Tunrue Village, after the implementation of the Village Financial System Application, it was found that there had been an increase due to the implementation of the principles of village financial management and balanced with compliance with applicable regulations when managing existing funds.
Evaluasi Implementasi Manajemen Stratejik Dengan Menggunakan Manajemen Berdasarkan Tujuan (MBO) Pada PT Beta Medical Sebagai Perusahaan Alat Kesehatan
Authors: Affar Muhammad
Published: September 2024

This study aims to determine the results of the evaluation of the implementation of strategies that have been implemented so far using Management by Objectif (MBO). This research was conducted at PT Beta Medical as a Medical Device Company in Indonesia. MBO is used in this study as an analytical tool because this company is a family company and this company is not so complex and not large-scale, only being the sole and non-single distributor of medical devices imported from the manufacturing countries. So to achieve this goal, this study uses a descriptive qualitative approach. Data collection techniques were carried out through interviews, observations, and documentation studies. Data analysis procedures are data reduction, data display, and verification. While the research subject is Mr. Andre Marthino, B.Mgt, MIB as the Marketing Director at PT Beta Medical and also as the son of the owner of the company PT Beta Medical, namely Mr. Drs. Ec. Amiruddin M. Noer, MBA. The results of this study indicate that the implementation of the strategy that has been implemented by PT Beta Medical is still very ineffective because the targets set by the company have not been achieved for the last two years. Most likely in the following year it will not be achieved. All of this can happen because the implementation process is not so good, clear and focused on each division which results in many obstacles and problems faced by the company.
DIGITAL DEXTERITY: STRATEGIC ENABLER YANG MENDORONG ORGANISASI MENUJU TRANSFORMASI DIGITAL
Authors: Asrunputri Aisyah Pia , Scorita Kurnia Budhy
Published: September 2024

The purpose of this study was to determine respondents' perceptions regarding digital dexterity in the workplace. The research also focuses on how digital dexterity includes critical skills such as mobilize, execute, transform, and agility. This type of research is exploratory-descriptive using 20 items of the 8 elements of the digital dexterity instrument developed by Capgemini Consulting. The results show that there are still many organizations that do not fully have adequate access to adapt to the digital era or the industrial revolution 4.0. This also prevents employees from receiving the training, facilities and infrastructure needed. Therefore, access to adequate technology, training and digital skills development are needed for employees to be able to create human resources that are ready to face the digital transformation needed.
Towards a new Ukraine?: substantive and value-oriented guidelines of Ukrainian constitutionalism in the post-war period
Authors: Krusian Anzhelika , Batanova Nataliia , Omelchenko Nataliia , Batanov Oleksandr , Kostetska Tetiana
Published: September 2024

The aim of the study is to analyze the substantive and value-oriented guidelines of modern Ukrainian constitutionalism in the post-war period. The relevance of the research is driven by the need to restore and reform Ukraine's legal system in the post-war period. Rebuilding the country requires not only physical reconstruction but also a rethinking and strengthening of the constitutional foundations upon which the state is built. The research methodology includes doctrinal research, comparative analysis, and empirical research methods. The study analyzed the shift in the values of Ukrainian constitutionalism in the post-war period. Key directions for the restoration and development of Ukraine's legal system were identified, including ensuring sovereignty, protecting citizens' rights and freedoms, developing democratic institutions, economic stability, national identity, international cooperation and integration, humanitarian support for war victims, and environmental sustainability. Challenges and opportunities facing Ukrainian society in the context of post-war recovery were analyzed, and measures to strengthen the legal order and democratic values were proposed.
Transformation of the content of the category of ‘artist’ in the modern era in philosophical and art historical discourse
Authors: Kalashnyk Mariya , Khirina Ganna , Soshnikov Andriy , Novikov Iurii , Savchenko Leonid
Published: September 2024

The article aims to explore the evolution of the concept of the artist from the Renaissance to the modern era, focusing on how cultural, philosophical, and socio-economic factors have redefined the artist's role in Western society. The study examines the shift from viewing artists as artisans or servants of religion and power to recognizing them as autonomous creators embodying individualism, creativity, and genius.

To achieve this, a multidisciplinary methodology was employed, integrating historical analysis, philosophical examination, and socio-cultural contextualization. The research draws on primary sources such as archival documents, artistic manifestos, and philosophical texts, alongside secondary sources including critical essays and historical analyses. The study's theoretical framework is grounded in concepts from art philosophy, socio-cultural theory, and intellectual history.

The results highlight significant transformations in the artist's status and self-perception, emphasizing the impact of Enlightenment ideas on creativity and individualism, the influence of socio-economic changes on artistic autonomy, and the evolving relationship between artists and their patrons. The article concludes that these shifts have had a profound and lasting impact on Western art philosophy and contemporary understandings of art and the artist.
KESULITAN KEUANGAN, KOMITE AUDIT, DAN FAKTOR LAINNYA YANG MEMENGARUHI MANAJEMEN LABA
Authors: Saputra Gerry , Rinjani Rinjani
Published: September 2024

This study was conducted to obtain empirical evidence on whether financial difficulties, audit committees and other factors affect profit management. The variety of independent variables used in this study includes financial distress, audit committee, leverage, financial stability, financial target, firm size, board size, and dividend payment. This study used a sample of 111 data from 37 companies listed in the Consumer Cyclicals and Consumer Non-Cyclicals sectors on the Indonesia Stock Exchange from 2020 to 2022. Sample selection in this study used purposive sampling and data analysis using multiple regression. Based on data analysis shows that dividend payments have an influence on profit management practices. In addition, other independent variables, such as financial hardship, audit committee, leverage, financial stability, financial targets, company size, and board size did not show any influence on profit management practices.
ALGORITHMS FOR SOLVING LINEAR CONSTRAINTS IN THE RING OF INTEGER NUMBERS
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, sl.krivoi@gmail.com, Kryvyi S.
Published: September 2024

The author proposes algorithms for constructing a pre-basis and the basis of the set of solutions for systems of linear constraints of the type of equalities and inequalities in the domains of integers, which are based on combined coefficients of constraints. The article considers the algorithm for constructing the pre-basis and basis of systems of linear equations and algorithms for constructing the fundamental system of solutions for systems of linear homogeneous and linear inhomogeneous inequalities. Keywords: ring of integer numbers, systems of linear constraints, algorithms.
A COMPLEX MATHEMATICAL MODEL OF THE VALUE OF FUNCTIONAL RELIABILITY OF FLIGHT CREW MEMBERS
Authors:   V.M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine, aralova@ukr.net, Chikriy A.O. , Aralova N.I. ,   V.M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine, g.chikrii@gmail.com, Shakhlina L.Ya.-G. ,   National University of Ukraine on Physical Education and Sport, Kyiv, Ukraine, sportmedkafedra@gmail.com
Published: September 2024

A complex mathematical model to determine the functional reliability of flight crew members is proposed. The components of the model are the model of control of oxygen modes in the human body, the model of transport and mass exchange of respiratory gases in the human body, the model of self-organization of the respiratory system, and the model of adaptation of the human body to extreme disturbances. It is shown that the model allows (given a corresponding data array) one to determine if a particular individual can adapt to work under extreme conditions of professional activity. Keywords: functional reliability of the pilot, functional respiratory system, mathematical model of the cardiorespiratory system, adaptation of the body to extremes, professional activity of the pilot.
Monitoreo de áreas de cultivo de maíz en la zona noroeste del Estado de México a través de sensores remotos
Authors: Cortez-Núñez Jocelyn Alejandra , Zepeda Mondragón Francisco , García Reyna Miguel Eduardo , Hernández-León Benjamín , Aguirre-Mendizabal Abraham
Published: September 2024

Debido al continuo crecimiento de la población mundial y como consecuencia el aumento de la demanda de alimentos se requiere que el sector agrícola sea eficiente y sostenible, es decir, que garantice la seguridad alimentaria, que promueva el desarrollo local y que disminuya la contaminación ambiental. Por otro lado, en la actualidad estamos viviendo una crisis climática global que ocasiona alteraciones en los ciclos hidrológicos y aumento de la temperatura, lo que está ocasionando pérdidas económicas en el sector agrícola. Por tal motivo, es necesario incorporar tecnologías modernas de la Agricultura de Precisión (AP) en las prácticas agrícolas tradicionales para mejorar el rendimiento y las ganancias de los agricultores, al mismo tiempo alcanzar beneficios ambientales. En este contexto, el presente estudio dio seguimiento al desarrollo fenológico y la salud del cultivo de maíz en parcelas del municipio de Atlacomulco, Estado de México, México a través de imágenes multiespectrales del satélite Sentinel-2 y un vehículo aéreo no tripulado (VANT). Se llevó a cabo un análisis espaciotemporal de índices de vegetación (IVs) con la finalidad de determinar su sensibilidad a los cambios del verdor del cultivo, en un entorno de condiciones reales. Además, las características agrícolas proporcionadas por los agricultores que manejan las parcelas se emplearon para confirmar los hallazgos. De igual forma, se detectó falta de homogeneidad en las parcelas evaluadas indicando una deficiencia de nutrientes o de agua en algunas de éstas. También, se analizaron las retrodispersiones polarizadas VH y VV del satélite Sentinel-1, demostrándose un potencial de la polarización VH ante la falta de datos de sensores ópticos debido a la nubosidad.
Índice de presión urbana sobre áreas naturales protegidas en México
Authors: Hernández Guerrero Juan Alfredo
Published: September 2024

La presión urbana sobre áreas naturales protegidas (ANP) comúnmente involucra aumento de población y superficie construida, concentración económica, cambio de uso y cobertura de suelo, mercantilización de recursos naturales, reducción o pérdida de biodiversidad, y reconfiguración productiva y cultural. Estas situaciones se acentúan según la dinámica urbana, la diversidad y tamaño de espacios urbanos y los sectores de incidencia. Es un problema común en países de América Latina, pero son escasos los estudios a escala nacional que identifican la presión que ejercen espacios urbanos de distinto tamaño  sobre ANP. Así, el presente trabajo identificó y representó la presión urbana que ejercen zonas metropolitanas sobre ANP en México. El proceso consistió en la elaboración de un índice de presión urbana sobre ANP con el uso de geoestadística y sistemas de información geográfica; recolección de datos, definición de indicadores, fiabilidad de los datos, manejo de imágenes de satélite y uso de  álgebra de mapas. En los resultados destacaron 30 zonas metropolitanas con presión urbana alta y muy alta, las cuales se relacionan con 8.5 ANP y la distancia hacia las ANP osciló entre 10.2 km. Asimismo, el sector central de México es la que presentó la mayor presión sobre ANP. Se concluye que la información generada puede acompañar regulaciones y políticas públicas para reducir presión sobre ANP y problemáticas ambientales.
WHEN QUIZWHIZZER IS USED EFFECTIVELY AT SMAN 1 BLITAR IN THE TENTH GRADE TO ENHANCE STUDENTS’ READING COMPREHENSION
Authors: Agung Cahyono Muh. Felix , Puspita Sari Hesty , Sutanti Nita , Supriyono
Published: September 2024

This research uses Quiz Whizzer to determine the effectiveness of Quiz Whizzer in improving the reading comprehension of recount text from 37 students in class X5 of SMAN 1 Blitar. The researcher wants to know the effectiveness of Quiz Whizzer in improving reading comprehension of recount text. The things the researcher wants to research include; finding the main idea, synonyms and antonyms, references, implied and explicit meaning, and concluding the reading text. The results show a significant increase in students' reading comprehension of recount text, this is proven by the average of 74.74 increasing to 83.84. Therefore, it can be recommended that teachers use Quiz Whizzer as an alternative learning medium as a medium for teaching and improving students' abilities.
Dismantling Silos: Academia, Industry, and a Science Museum Working Together
Authors: Zimmerman Thomas , Yu Kristina , Carrison-Stone Dana , Erwin Jonathan , Ma Joyce , He Zachary Hui , Bianco Simone , Esquerra Raymond , Capponi Sara
Published: September 2024

A partnership between four universities, an industrial research lab, and a public science museum, created as a National Science Foundation Science and Technology Center, offers diverse collaboration and learning opportunities in cellular engineering. Each institution plays a vital role: universities advance science education, industry develops and commercializes technologies based on basic research, and science museums educate and engage the public. However, differences in the culture, values, and focus of these institutions create collaboration challenges. Three workshops highlight how consistent funding, intellectual property agreements, shared facilities, and long-term collaborations can harness the strengths of each institution to promote rapid prototyping, confront global problems, and encourage commercial applications from research.
Using a Structured Research Framework to Improve Mentoring Capacity in a Biophysics Research Lab
Authors: Elliott Truitt , Drolet Erin , Briganti Jonathan S. , King Kelsie M. , Brown Anne M.
Published: September 2024

Undergraduate research experiences (UREs) cultivate workforce skills, such as critical thinking, project management, and scientific communication. Many UREs in biophysical research have constraints related to limited resources, often resulting in smaller student cohorts, barriers for students entering a research environment, and fewer mentorship opportunities for graduate students. In response to those limitations, we have created a structured URE model that uses an asynchronous training style paired with direct-tiered mentoring delivered by peers, graduate students, and faculty. The adaptive undergraduate research training and experience (AURTE) framework was piloted as part of the Brown Experiential Learning program, a computational biophysics research lab. The program previously demonstrated substantial increases and improvements in the number of students served and skills developed. Here, we discuss the long-term effectiveness of the framework, impacts on graduate and undergraduate students, and efficacy in teaching research skills and computational-based biophysical methods. The longitudinal impact of our structured URE on student outcomes was analyzed by using student exit surveys, interviews, assessments, and 5 years of feedback from alumni. Results indicate high levels of student retention in research compared with university-wide metrics. Also, student feedback emphasizes how tiered mentoring enhanced research skill retention, while allowing graduate mentors to develop mentorship and workforce skills to expedite research. Responses from alumni affirm that workforce-ready skills (communicating science, data management, and scientific writing) acquired in the program persisted and were used in postgraduate careers. The framework reinforces the importance of establishing, iterating, and evaluating a structured URE framework to foster student success in biophysical research, while promoting mentorship skill training for graduate students. Future work will explore the adaptability of the framework in wet lab environments and probe the potential of AURTE in broader educational contexts.
Herida cervical transfixiante por arma de fuego sin lesiones graves asociadas. Un resultado inesperado a una lesión potencialmente mortal.
Authors: MATURANA ARANCIBIA JUAN CARLOS , Saffie Conteras Belén , HECHT LÓPEZ PEDRO
Published: September 2024

Objetivo: Presentar un caso clínico de un paciente con herida por arma de fuego cervical transfixiante sin lesiones graves ni evidencia en la literatura nacional.Introducción: Las lesiones cervicales traumáticas por arma de fuego presentan elevada morbimortalidad, con secuelas físicas que requieren la atención de un equipo médico quirúrgico altamente entrenado.Caso clínico: Paciente masculino de 43 años, ingresa hemodinámicamente estable al servicio de urgencias, por traumatismo cervical transfixiante por arma de fuego sin lesiones neurovasculares.  Al examen físico se aprecia herida penetrante de aproximadamente 2 x 2cm con entrada por triangulo anterior derecho y salida por línea media cervical posterior. El paciente evoluciona favorablemente sin complicaciones, siendo dado de alta al tercer día.Conclusión: La presentación clínica de una herida cervical por arma de fuego debe siempre hacer sospechar de un gran daño de tejidos y obliga a descartar lesiones neurovasculares. La evolución excepcional es el alta temprana sin secuelas ni lesiones graves asociadas como fue el caso clínico.
Indicación de biopsia de linfonodo centinela en CDIS de mama. Estudio cooperativo de factores predictivos de hallazgo de carcinoma invasor postoperatorio.
Authors: Guesalaga Ruiz-Tagle Paz , Fernández Thiers Sebastián , Rodríguez Gutiérrez Javier Ignacio , Camus Appuhn Mauricio , Sánchez Rojel César , Acevedo Claros Francisco , Merino Lara Tomás , Abud Pérez Maritza , Domínguez De Landa Angélica , Domínguez Covarrubias Francisco
Published: September 2024

Introducción:El carcinoma ductal in situ (CDIS) de la mama es un precursor del carcinoma invasor,  representando el 20-25% de los diagnósticos de cáncer de mama. La biopsia percutánea preoperatoria no siempre identifica focos de invasión, por lo que informe postoperatorio de carcinoma invasor implica otra cirugía para biopsia de linfonodo centinela (BLC).El objetivo del trabajo es analizar factores clínico-patológico-radiológicos de pacientes con diagnóstico preoperatorio de CDIS que permitan predecir el riesgo de carcinoma invasor postoperatorio y en quienes sería necesario realizar BLC para evitar otra cirugía.Métodos:Se realizó un estudio retrospectivo de 304 pacientes con diagnóstico preoperatorio de CDIS mediante biopsia percutánea en nuestra institución entre 2007 y 2021. La asociación entre las variables y el diagnóstico de carcinoma invasor en el postoperatorio fue analizada con modelos de regresión logística usando análisis univariado y multivariado.Resultados:Se identificaron 304 pacientes con diagnóstico de CDIS puro en la biopsia percutánea. De ellos, 85 (28%) presentaron carcinoma invasor en el análisis postoperatorio.En el análisis multivariado la edad (OR 1,06; IC 95% 1,01-1,11), tamaño de la lesión (OR 1,03; IC 95% 1,01-1,05) y receptores hormonales negativos (OR 5,47; IC 95% 1,61-18,56) resultaron estar asociados a un mayor riesgo de componente invasor postoperatorio.Conclusión:En pacientes con CDIS, las variables edad, tamaño y estado de receptores hormonales son factores pronósticos para encontrar invasión en el estudio postoperatorio. Por lo tanto, deben ser considerados al decidir el tratamiento quirúrgico.
Corporate management of enterprises: a value-oriented approach
Authors: Dzoba Oleh
Published: September 2024

The article substantiates the relevance of the study of corporate value-oriented management, the concept of which is based on the need to take into account the interests of all market participants and is the basic identifier of sustainable and efficient functioning of organizations. The essence and main approaches to the interpretation of the concept of "corporate management" are defined, the basic principles and advantages of corporate management as one of the factors of enterprise development are identified. It is proved that corporate management in the modern world is an integral part of any organization and includes a heterogeneous system, which can be used to predict possible scenarios in organizations operating in national and international markets, taking into account specific industry and mental nuances. It is substantiated that the effectiveness of the applied methods and management techniques depends on the model of corporate governance of the company used by the company's management. The features and correlation of the concepts of "corporate administration" and "corporate management" are characterized. A comparative analysis of corporate management models is presented and a national model of corporate management is built, which takes into account the national peculiarities of the development of market relations in Ukraine and the mental traits of the population. The key aspects of implementing a value-oriented approach in the activities of an enterprise are analyzed, its main elements are identified, and the key principles and criteria for effective corporate governance are described. The asset, liability and balance sheet of enterprises operating in the field of crude oil and natural gas production for 2013-2022 are analyzed. It is proved that effective corporate management opens up fundamentally new business development opportunities for the company: improving the financial performance of the company due to higher productivity or profitability, invested capital and its development. The factors that influence the formation and functioning of the national model of corporate management are determined.
Tactical planning experience in the system of circular business models of enterprises
Authors: Maslak Oleksandr , Vorovonska Marta , Malyk Maksym
Published: September 2024

Introduction. In modern economic conditions, which are characterized by the exacerbation of socio-economic and environmental problems and an increase in the level of social responsibility of business, it is important to ensure careful handling of resources, their repeated consumption, innovative approaches to production and enterprise management, etc. This corresponds to the concept of the circular economy, embodied in the circular business models of enterprises.
In the conditions of revitalization of the European integration processes, the problems of the formation and development of the circular economy in Ukraine are being actualized, which requires the study of the EU action plan for the circular economy in general and its individual directions in order to determine the level of its implementation according to various components of the course of circular business processes at domestic enterprises.
Purpose. In accordance with the outlined problems, the article should study the domestic and foreign experience of tactical planning in the system of circular enterprises.
Method (methodology). To achieve the goals, the article uses a theoretical generalization, an arithmetic and logical method of researching statistical data of the National Bank of Ukraine, the State Statistics Service of Ukraine, UkrINTEI, etc., as well as methods of analysis, synthesis, comparison, and systematization. Histograms and dot charts built in the MS Excel were chosen for graphical representation of the obtained results. This ensured the formation of conclusions of the research.
Results. Based on the results of the analysis, the following conclusions were drawn in the article: in the studied period, a decrease in the level of waste is characteristic, which contributes to the establishment of an ecological balance, but is accompanied by the export of waste, which causes concern; a gap in the research is a comparison of the costs of environmental protection in EU countries and Ukraine, which did not publish such data during the period of the military invasion of the Russian Federation and martial law; comprehensive reforms and tactical plans of the circular economy of the EU are aimed at the emergence of new markets for goods and services and an increase in the level of employment, which has no resonance during the period of martial law in Ukraine; in 2023, a 5.3% increase in GDP is observed, which is associated with the volume of international aid, increased productivity, the development of alternative export routes and is not a consequence of the implementation of tactical measures of the circular economy; there is a significant potential to increase the innovative activity of enterprises, the development of cooperation between innovative enterprises and research institutions, the development of scientific and technological cooperation, entrepreneurship between Ukraine and the EU, which will contribute to the achievement of circular economy tactical plans.
Investment lending for small and medium-sized businesses in Ukraine under martial law: challenges and prospects
Authors: Mykhaylo Yarish
Published: September 2024

Introduction. The article analyzes the financial and credit levers supporting investment lending for small and medium-sized businesses (SMBs) in Ukraine under martial law. In particular, it examines the "Affordable Loans 5-7-9" program, mechanisms of state guarantees, and refinancing, as well as their role in ensuring the stability and development of SMBs during the war. Special attention is paid to assessing the current state and problems of bank investment lending to SMBs, as well as the development of effective monetary-credit instruments to stimulate this process.
The purpose of the article is to study the current state and problems of bank investment lending to small and medium-sized businesses in Ukraine under martial law, as well as to identify effective monetary-credit instruments and financial levers to activate it.
Methodology: General scientific methods of cognition are used in the research process, namely: methods of analysis and synthesis to assess the current state of investment lending to SMBs; comparison – to analyze the effectiveness of various financial and credit mechanisms; content analysis – to assess the impact of state programs and mechanisms on the stability and development of SMBs; generalization – to formulate recommendations for improving financial and credit support.
Results: It has been proven that the implementation of state support programs, such as "Affordable Loans 5-7-9," has significantly contributed to the stabilization and development of small and medium-sized businesses under martial law. Additionally, the development and implementation of long-term refinancing programs by the National Bank of Ukraine for state banks, the establishment of a development bank based on JSC "Ukrgasbank," and the introduction of a guaranteed debt mechanism for banks raising funds on international capital markets have substantially enhanced the possibilities of financing investment projects. Proposed ways to modernize existing state programs supporting investment lending take into account the need to develop infrastructure, ensure energy independence, and strengthen the military-industrial complex.
The impact of digital technologies on business development: transformation of business models and management of innovative projects
Authors: Zdrenyk Vasyl , Grod Andriy , Ocheretko Borys , Bohonskyi Volodymyr
Published: September 2024

Introduction. The article examines the impact of digital technologies on business development, particularly the transformation of business models and management of innovative projects in the context of globalization and rapid technological changes.
Objective. To investigate the main trends, challenges, and prospects of digital business transformation, and to analyze successful examples of digital technology implementation by Ukrainian enterprises.
Research Methods. The study employed methods of analysis and synthesis of scientific literature, case studies, and comparative analysis of successful practices.
Results.The key factors for successful digital transformation were identified, major obstacles for Ukrainian enterprises were highlighted, and future research perspectives in this field were outlined.
Herramientas pedagógicas para la enseñanza del lenguaje musical a personas con discapacidad visual que aspiran acceder a un pregrado en música
Authors: Ardila-Quiñonez Yazmin-Rossana , Ochoa-Valencia Friedrick , Álvarez-Osorno Jorge-Elicer , Tamayo-Medina Felipe
Published: September 2024

La investigación se enfoca en la recopilación de los recursos pedagógicos utilizados actualmente para la enseñanza musical a personas con discapacidad visual. A partir de lo anterior, se realiza un análisis de las problemáticas y dificultades que existen con estos materiales. Posterior al análisis del material existente, se propone un material pedagógico para la enseñanza de lenguaje musical en el sistema Braille adaptado a las necesidades actuales de los estudiantes de nivel medio ha avanzado que cuentan con una discapacidad visual. Este material cuenta con herramientas prácticas e innovadoras como el uso de las tecnologías de la información y la comunicación (TIC), las cuales facilitan la comprensión de diversos elementos sonoros para las personas con discapacidad visual (Gorbunova y Voronov, 2018). Con estas herramientas los estudiantes con discapacidad que deseen presentar un examen de admisión para un pregrado en música del Área Metropolitana del Valle de Aburrá tendrán las competencias requeridas en lectura rítmica y rítmico-melódica para afrontar dicho examen.
APICAL DEBRIS EXTRUSION FOLLOWING ENDODONTIC TREATMENT BY XPENDOSHAPER FILES: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Authors: Bhayani Maitri , Hegde Vibha , Dedhia Henal
Published: September 2024

Aim : The review aims to determine the relevant position of XPS in terms of apical debris extrusion and how it fares in comparison with the other file systems. Methods : A systematic search used keywords ("Debris extrusion" AND "XP Endo Shaper") across databases like MEDLINE, PubMed, PubMed Central, Web of Science, and Google Scholar. The inclusion and exclusion criteria was stringent to conduct the filtering and select the in-vitro, RCTs etc which were eligible for qualitative and subsequent quantitative analysis. Results : A total of n=5 studies were identified after a critical assessment of articles for the inclusion and exclusion criteria. The standard mean Difference is 1.66 (0.54 – 2.77) and the pooled estimates favour other file systems. This signifies that the debris extrusion is on average 1.66 times more by other file systems as compared to XP endo shapers file and this difference is statistically significant (p<0.05). By employing the random effect model the I2 statistic showed 97%, the heterogeneity for Tau2 was 1.56, x2 being (p<0.0001) and the overall effect for Z value being 2.91 (p=0.004). Conclusion: XP-Endo Shaper demonstrates efficiency in challenging anatomies while minimizing debris. It shows less debris extrusion than rotational systems, though more than reciprocating ones
KNOWLEDGE MANAGEMENT RISKS. A CLUSTER ANALYSIS DURING COVID-19 AND AFTER.
Authors: Ursache Vlad Mihai
Published: September 2024

The year 2024 and the knowledge management risks associated with organizational knowledge management still
require further and deeper analysis. Despite numerous studies in the field of knowledge risk management, this area
remains challenging and dynamic, particularly in the current era of transition and unpredictable times. This paper seeks
to analyze the academic research over the past four and a half years (2020-2024), highlighting the knowledge risks
analyzed in this period the relevant connections between terms like knowledge management, knowledge risks, and
knowledge dynamics. The primary purpose is to identify what knowledge risks caught researchers' attention during
these times of transition and ongoing change when uncertainties are more common than they first appear, making it
harder to calculate and not mention analyzing knowledge risks. The academic literature agrees on the importance of
knowledge risk management in the knowledge management domain, where risks take on greater significance and the
fact that they are crucial to any organization's management. In current times of transition and continuous change, when
knowledge risks are increasingly prevalent and crises are occurring more frequently than predicted, we question how
difficult it will be in the following years for a knowledge management system, particularly when it comes to managing
knowledge risks from new areas such as 'Artificial Intelligence'.
WASTE HEAT RECYCLING MANAGEMENT
Authors: Alexandru Daniel,
Published: September 2024

In the current context of increasing concerns regarding energy efficiency and environmental impact,the management
of waste heat recovery is essential for various industries. This article explores modern methods and technologies for
waste heat recovery,focusing on energy efficiency and sustainability.We examine processes for capturing and reusing
waste heat from industrial and commercial sources, assessing their impact on overall energy consumption and
greenhouse gas emissions.The study includes a review of relevant literature, case studies, and recent implementations
of waste heat recovery technologies.The conclusions highlight the economic and ecological benefits of efficient waste
heat management and provide recommendations for optimizing industrial processes to enhance energy performance.
This article aims to offer an integrated perspective on waste heat management practices, thereby contributing to the
development of innovative and sustainable solutions for the industry.