bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Therapeutic Cushion Using Chrysopogon Zizanioides (Vetiver) and Bamboo Fabric
Authors: B Jeyanthi , Chinnammal S Karpagam , R Karthikselvam
Published: May 2020

Textile is the key component of every human life from birth to last rights. In the recent decade, textile sectors have shown tremendous growth through improved technology from raw materials to product design and manufacturing process. These extraordinary developments provide a path to find an innovative solution to the medical sector especially in the field of therapeutic textiles. This project is a small initiative to confer a solution for particular workforce such as truck drivers who are suffering from hemorrhoids disease. The main aim was to find an innovative therapeutic textile solution for this ailment based on ancient method of herbal treatment.
Determination of the absorption cross-sections of higher order iodine oxides at 355 nm and 532 nm
Authors: Lewis Thomas R. , Gómez Martin Juan Carlos , Blitz Mark A. , Cuevas Carlos A. , Plane John M. C. , Saiz-Lopez Alfonso
Published: May 2020

Abstract. Iodine oxides (IxOy) play an important role in the atmospheric chemistry of iodine. They are initiators of new particle formation events in the coastal and polar boundary layer and act as iodine reservoirs in tropospheric ozone-depleting chemical cycles. Despite the importance of the aforementioned processes, the photochemistry of these molecules has not been studied in detail previously. Here, we report the first determination of the absorption cross sections of IxOy, x = 2, 3, 5, y = 1–12 at λ = 355 nm by combining pulsed laser photolysis of I2/O3 gas mixtures in air with time-resolved photo-ionization time-of-flight mass spectrometry, using NO2 actinometry for signal calibration. The oxides selected for absorption cross section determinations are those presenting the strongest signals in the mass spectra, where signals containing 4 iodine atoms are absent. The method is validated by measuring the absorption cross section of IO at 355 nm, σ355 nm, IO = (1.2 ± 0.1) ×  10–18 cm2, which is found to be in good agreement with the most recent literature. The results obtained are: σ355 nm, I2O3
The sensitivity of intense rainfall to aerosol particle loading – a comparison of bin-resolved microphysics modelling with observations of heavy precipitation from HyMeX IOP7a
Authors: Kagkara Christina , Wobrock Wolfram , Planche Céline , Flossmann Andrea I.
Published: May 2020

Abstract. Over the Cévennes–Vivarais region in southern France 5 h
intensive rainfall covering an area of 1000 km2 with more than 50 mm
of rain accumulation was observed during IOP7a of HyMeX. This study evaluates
the performance of a bin-resolved cloud model for simulating this heavy-precipitation event. The simulation results were compared with observations
of rain accumulation, radar reflectivity, temporal and spatial evolution of
precipitation, 5 min rain rates, and raindrop size distributions (RSDs).
The different scenarios for aerosol number concentrations range from 1000 to
2900 cm−3 and represent realistic conditions for this region. Model
results reproduce the heavy-precipitation event with respect to maximum rain
intensity, surface area covered by intense rain and the duration, as well as
the RSD. Differences occur in the short-term rainfall rates, as well as in
the drop number concentration. The cloud condensation number concentration
has a notable influence on the simulated rainfall, on both the surface
amount and intensity but also on the RSD properties, and should be taken into
account in microphysics parameterizations.
Mitochondrial disease: Replacing the powerhouse of the cell
Authors: Frederick Mallory
Published: May 2020

The mitochondria are called the powerhouses of the cell because they make most of the energy required by our cells. Diseases caused by mitochondrial mutations always occur in the children of women with mitochondrial disease and, due to this central role in energy production, can be extremely detrimental. A recently developed preventative therapy, mitochondrial replacement therapy, reduces carryover of mitochondrial disease from mother to child. Though these “three-parent babies” are born without mitochondrial disease, this type of gene editing carries ethical implications and unexplored effects on future generations.
Informarse en el smartphone: estrategias de lectura transmedia por parte de jóvenes universitarios del Aglomerado Gran Buenos Aires
Authors: Albarello Francisco Javier
Published: May 2020

El consumo de noticias se ha transformado sensiblemente en los últimos años, en virtud de la multiplicación de dispositivos a través de los cuales se accede a la información, los cambios en los modos de contar las noticias y la creciente importancia del software en la gestión de la información. El smartphone es el principal medio de acceso a las noticias por parte de los jóvenes universitarios del Aglomerado Gran Buenos Aires, quienes despliegan estrategias de lectura particulares a la hora de informarse. Los jóvenes navegan aprovechando la especificidad que le ofrece cada dispositivo en el modo de presentar las noticias y lo mejor de cada uno. En ese sentido, la “lectura transmedia” parece ser la forma que asume la relación que se establece con esos contenidos, puesto que los relatos noticiosos se despliegan en múltiples plataformas y se completan con la participación activa de los usuarios, quienes ponen en diálogo esas distintas plataformas, comparten las noticias en las redes sociales y producen contenidos relacionados con sus temas de interés. En esta investigación exploratoria, procuramos describir y analizar las prácticas de consumo de noticias que realizan los jóvenes a través del smartphone mediante 16 entrevistas en profundidad realizadas a estudiantes de diversas universidades del país. Del análisis de las entrevistas se desprende que los jóvenes despliegan estrategias de lectura habituales en las que alternan entre la exposición y la interacción, entre la lectura superficial y la lectura profunda, y entre la búsqueda de información y entretenimiento.
Postnesting migration routes and fidelity to foraging sites among loggerhead turtles in the western North Atlantic
Authors: Phillips Katrina F , Addison David S , Sasso Christopher R , Mansfield Katherine L
Published: May 2020

Although the western North Atlantic hosts the largest nesting assemblage of loggerhead turtles (Caretta caretta) in the world, their fine-scale habitat use beyond the nesting beach and how it effects reproductive output is still poorly understood. To characterize internesting
and postnesting habitats used by loggerheads in the region, we satellite tracked 32 individual mature female turtles from a nesting beach in the southeastern Gulf of Mexico from 2009 to 2016. Thirteen of these turtles were tagged and tracked for two or more nesting seasons to assess fidelity
to internesting movements, migratory pathway, and foraging site. Internesting movements for all turtles occurred over the West Florida Shelf in relatively close proximity to the nesting beach. Migratory pathways along the continental shelf led to foraging areas in four distinct regions: the
southeastern Gulf of Mexico (n = 16 turtles), northeastern Gulf of Mexico (n = 8), Bahama Banks (n = 7), and Campeche Bank (n = 1). Individual turtles exhibited high fidelity to foraging sites across seasons, and 22 of the 32 tracked turtles shared overlapping foraging
area utilization with at least one other individual during the tracking period. Loggerheads foraging closest to the nesting beach in the southeastern Gulf of Mexico were generally smaller than those foraging in other regions. This work highlights the importance of the West Florida Shelf for
eastern Gulf of Mexico sea turtle rookeries. Identifying and managing the multiple in-water habitats used within and between nesting seasons will help sustain loggerhead turtle population recovery and maintenance.
n. 25 - O DISCURSO AUSENTE DE DEMOCRACIA NA BASE NACIONAL COMUM CURRICULAR DO ENSINO FUNDAMENTAL
Authors: Santos Emina , Tomé Luane
Published: May 2020

Este trabalho tem o objetivo de compreender como a função social da escola enquanto espaço de formação para a democracia é concebida na Base Nacional Comum Curricular (BNCC) do ensino fundamental. A pesquisa se caracteriza como de natureza documental e investiga como o conceito de democracia se estabelece enquanto princípio para implementação e garantia de um espaço escolar democratizante. Constatamos que a articulação dos conteúdos do documento com princípios da gestão democrática apresentam-se de forma superficial e inconsistente na Base. Nesse sentido, indica-se que a democracia é apresentada como um conceito vago e com argumentação frágil no texto, ao invés de ser trabalhada como um construto social.
The Presentation of Shoah Events to Students at Various Educational Levels: A Review
Authors: Mašát Milan , Sladová Jana , Šmakalová Kristýna , Bínová Anna
Published: May 2020

The review study deals with the presentation of methods of acquainting pupils and students with the Shoah events at various levels of institutional education. Based on the opinions and positions of leading experts on the subject, we summarize the most important methods in the field. In the introduction we present the importance of one line of the events of World War II in the 21st century world: the defined phenomenon can be perceived as a warning against certain forms of stigmatization, ostracism or as a warning against the need to protect democratic political order. In the paper we define the terms Shoah, Holocaust, anti-Semitism and racism. We also deal with the Israeli public schools in the area of teaching about the Shoah, with the curricular anchorage of the terms Shoah and Holocaust and with the potential of Literary Education in the field of Shoah presentation. We believe that the educational system of the Jewish state can be a model in the area of implementation of the defined phenomenon for the educational systems of other countries. At the same time, we summarize the most important research surveys dealing with the teaching of the Shoah in Israel. In the area of methods are in more detail introduced “The Survivors´ Heritage”, “The Historical Approach”, “Multi-Level Approach” and “An Interdisciplinary Approach”.
Referenciais utilizados nas teorias de médio alcance: revisão integrativa
Authors: Tonin Luana , Batista Josemar , Lacerda Maria Ribeiro , Cruz Elaine Drehmer de Almeida , Mantovani Maria De Fatima , Do Nascimento Jaqueline Dias
Published: May 2020

Objetivo: Identificar os referenciais teóricos utilizados nos estudos primários da enfermagem brasileira para o desenvolvimento de Teorias de Médio Alcance. Método: Revisão integrativa de literatura, com coleta de dados no Banco de Teses da Coordenação de Aperfeiçoamento Pessoal de Nível Superior e na Biblioteca Digital Brasileira de Teses e Dissertações do Instituto Brasileiro de Informação em Ciência e Tecnologia, realizada entre os meses de setembro e novembro de 2018. Resultados: Após seleção dos 6.498 estudos recrutados, quatro abordavam Teorias de Médio Alcance na Enfermagem. Dentre os referenciais teóricos, dois utilizaram a Teoria do Alcance de Metas de Imogene King e dois o Modelo da Adaptação de Roy. Conclusão: Observou-se que os referencias utilizados para a construção das Teorias de Médio Alcance nos estudos primários da enfermagem brasileira foram o de Alcance de Metas de Imogene King e o Modelo de adaptação de Roy.
A Contrastive Analysis of Interpersonal Function Between the Chinese and English Versions of The Sight of Father’s Back
Authors: Xin Lijun , Gao Jun
Published: May 2020

As a reminiscent prose, The Sight of Father’s Back was written by the modern writer, Zhu Ziqing, in 1925. A wave of warm current floods a large body of readers since this essay describes, in earnest, love of father. This research performs a contrastive analysis of interpersonal function between the Chinese and English versions of The Sight of Father’s Back in terms of mood, modality, and evaluation meanings. We find that mood and evaluation meanings display parallel distribution. Declarative and exclamatory moods occur most frequently in both the Chinese and English versions, whereas interrogative mood is at a premium. Besides, various evaluative adjectives and adverbs are used in both versions. However, modality shows remarkable discrepancies. The English version tends to adopt modal verbs with median-and-low value, while most median-and-high value modal verbs are presented in the Chinese version. In our view, the exercise of median-and-high value modal verbs reflects the thoughts more directly. While the selection of median-and-low value modal verbs might be concerned with the need for politeness. Besides, diverse choices of modal verbs are incident to various modal meanings along with research purposes.
Hamsun i sør og Hamsun i nord. Kunsten å argumentere for et diktersenter
Authors: Egeland Marianne
Published: May 2020

In 2005, two ambitious local initiatives were launched that independently of each other argued for establishing a national centre in their particular community to commemorate Nobel laureate Knut Hamsun (1859–1952): one in Grimstad on the southern coast of Norway, and the other at Hamarøy in northern Norway. Both places boasted a special ownership to the world famous author, but only the northern initiative materialized and a new museum opened in time for Hamsun’s 150 year anniversary. Why did Grimstad’s project fail and Hamarøy’s succeed? How did The Knut Hamsun Centre in Hamarøy follow up their stated goals and ambitions when planning the exhibitions? And how did Grimstad motivate plans for a downscaled centre several years later? A major issue in the article as well as in the discussion of the projects, is how the initiators argue for celebrating an author who supported Hitler and the Nazis during the war. Rhetorical and textual analysis of four documents offer insight into deliberations of how to exhibit a problematic legacy.
Big Data im Personalmanagement
Authors: Götz Thomas
Published: May 2020

Das Werk erarbeitet ein transparentes Regelungskonzept zur Umsetzung von Big-Data-Analysen (auch „People-Analytics“) im Personalwesen. Ausgehend vom abstrakten Datenschutzrecht werden anhand konkreter Anwendungsbeispiele Lösungen entwickelt, die den Interessenausgleich zwischen Arbeitgeber, Arbeitnehmern und Betriebsrat praxisnah ermöglichen. Dies gelingt durch die technische und organisatorische Trennung von Datenanalyse und Ergebnisdarstellung („informationelle Gewaltenteilung“), zu der die Akteure kraft Betriebsvereinbarung verpflichtet werden. Daneben untersucht das Werk Besonderheiten der betrieblichen Mitbestimmung bei der algorithmischen Verarbeitung von Beschäftigtendaten.
Selbstbestimmt in Gottes Willen
Authors: Mintken Tammo Elija
Published: May 2020

Drawing from Edmund Husserl´s ethical reflections the study thematizes a phenomenologically deepened understanding of moral autonomy and allows a critique of arbitrary autonomy. The best possible life of reason and the categorical imperative not only requires a cultivated heart but it is also continuously connected to reflection, critique and renewal of traditionally sedimented means and values of the life-world. In the face of existential threats like irrationality, sin and death personal individuality is realized by means of the absolute ought. Instead of social isolation vocational communitization and the alignment with the idea of God fulfil the truth of will of the personal within her world-life.
Physical Health Status of Emergency Care Providers in South Africa
Authors: Mthombeni Solomon , Coopoo Yoga , Noorbhai Habib
Published: May 2020

Background: Emergency care providers (ECPs) have a physically, mentally, and emotionally demanding profession. Therefore, they are predisposed to cardiovascular and other non-communicable disease risk factors. Objectives: The objective of the study was to determine the physical health status of ECPs in the North West province of South Africa through a selected anthropometric and other health parameter test battery. Methods: Ninety-one ECPs (64 males, 27 females) took part in the study voluntarily for health screening tests including body mass index (BMI), lean body mass (LBM), resting heart rate (RHR), blood pressure (BP), skinfold measurement, waist circumference (WC), waist-to-hip ratio (WHR), fasting blood glucose (FBG), and total cholesterol (TC). The collected data were subjected to statistical analysis using the Statistical Package for Social Sciences (SPSS) version 25 (IBM). Results: The participants demonstrated a mean BMI of 28.2 ± 5.5 kg/m2, body fat of 26 ± 7.6 %, and LBM of 58.6 ± 10 kg. Significant differences were seen in height (170.5 ± 6.2 vs. 160.7 ± 5.3 cm), BF% (22.5 ± 5.3 vs. 34.2 ± 6.2 %), and LBM (62.3 ± 8 vs. 49.2 ± 8.2 kg) between males and females (P ≤ 0.05). Mean systolic BP was 122 ± 15 mmHg, and diastolic BP was 81 ± 10 mmHg. Mean WC was 90.8 ± 11.4 cm. Other health parameters included mean FBG of 5.1 ± 2.4 mmol/L and mean TC of 4.9 ± 0.7 mmol/L. Significant differences were seen in WHR (0.88 ± 0.04 vs. 0.79 ± 0.06) between males and females (P ≤ 0.05). Conclusions: A significant number of ECPs presented with cardiovascular and other NCD risk factors such as hypertension, obesity, high WC, elevated FBG, and abnormal levels of TC. This can be attributed to the nature of their occupation such as working irregular shifts leading to sleep deprivation, being exposed to psychological trauma, poor nutrition during shifts, and/or lack of exercise. Stress management is an important part of these workers’ rehabilitation program. A well-formulated employee wellness program is required to set remedial measures in place.
An Unusual Variant of Lemierre’s Syndrome with Multiple Abscesses and Hepatic Vein Thrombosis
Authors: Hammami Fatma , Koubaa Makram , Zeyni Abrakhom , Chakroun Amal , Rekik Khaoula , Marrakchi Chakib , Ben Jemaa Mounir
Published: May 2020

Introduction: Lemierre’s syndrome is an uncommon, life-threatening disease that develops as a severe complication of oropharyngeal infection. However, this syndrome has also been reported during anaerobic septicemia, originating from diverse sources of infection, such as the gastrointestinal system. The diagnosis of this syndrome remains challenging, and is often prompted by the detection of Fusobacterium necrophorum in blood culture, rather than with clinical signs or symptoms. Case Presentation: A previously healthy 38-year-old woman was hospitalized for a 6-day history of fever, watery diarrhea, and vomiting. Physical examination of the patient showed fever, pharyngitis, and diffuse abdominal tenderness. Laboratory investigations revealed elevated inflammatory markers, and two blood cultures revealed Fusobacterium necrophorum. An abdominal ultrasound showed a liver abscess and hepatic vein thrombosis. The thoracoabdominal and cerebral computed tomography scan confirmed the results of the abdominal ultrasound. It additionally revealed bilateral lung nodules and a parietal brain abscess. The patient’s general condition and her laboratory test results, improved after receiving treatment with ceftriaxone and metronidazole. She received antibiotics for three months, without anticoagulation therapy. Repeated computed tomography scans showed a resolution of the liver, pulmonary, and brain abscesses, as well as the recanalization of the hepatic vein. Conclusions: Lemierre’s syndrome emerges as a result of septic illness and liver abscesses in case of gastrointestinal symptoms despite the lack of common presentation.
Frequency of Coronavirus NL63 Infection in Children with Upper Respiratory Infection by Real-Time PCR
Authors: Mohammadi Mahtab , Arabzadeh Seyed Ali Mohammad , Mollaei Hamid Reza , Monavari Seyed Hamidreza , Nikpour Najmeh
Published: May 2020

Background: Human coronavirus NL63 (HCoV-NL63) is a new respiratory virus associated with acute respiratory infection in children. Infection with this virus is usually accompanied by upper and lower infections of the respiratory tract in adults. Objectives: In a retrospective study, we investigated the incidence of coronavirus infection in children under the age of five years. Methods: We collected 138 specimens (nasal and throat swabs) from children less than five-years-old with acute respiratory infection from October 2018 to December 2019. Then, HCoV-NL63 was investigated using real-time PCR. Results: Out of 138 samples, 33 (23.9%) were positive for coronavirus NL63, including 21 (63.6%) male samples and 12 (36.4%) female samples. There was no significant correlation between gender and positivity for coronavirus infection (P > 0.05). However, the association of clinical symptoms with the virus was statistically significant (P < 0.05). Conclusions: This study was conducted for the first time in Kerman Province. In this study, the frequency of coronavirus NL63 was evaluated among children with acute respiratory infection with a highly sensitive method, real-time PCR. The prevalence of this virus was 33%, which was more frequent than in similar studies.
Pancreatic Adenocarcinoma Growth Retardation in a Psoriasis Patient on Ustekinumab
Authors: Sheriff Tabrez , Thomas David , Murrell Dedee F
Published: May 2020

Introduction: The use of a biologic agent, ustekinumab, for psoriasis has lead to an observation of tumor growth retardation in a patient with unresectable pancreatic cancer. High circulating levels of interleukin-23 have been found in certain cancers. Case Presentation: This case report of an 86 year old gentleman with psoriasis and pancreatic cancer highlights a pre-liminary role of interleukin 23 blockade in altering the tumor microenvironment of certain cancers to influence their growth and metastases. Conclusions: 29 months since his diagnosis this patients remains well with no metastases, no secondary symptoms from an obstructive malignancy, and has demonstrated no significant tumor progression despite no curative therapy. Ustekinumab has been the only immunotherapy he has received since his diagnosis and his existing medications remained unchanged. Preliminary evidence for interleukin 23 inhibition and tumor retardation is present however larger studies investigating in vivo levels of interleukin 23 in cancer patients and subsequent blockade is necessary to substantiate a possible new target in pancreatic cancer.
Key Performance Indicators Related to the Quality of Life in Patients with Celiac Disease: A Descriptive-Analytical Study
Authors: Jahhantigh Farnaz , Behmaneshpour Fateme , Gharebaghi Fatemaeh
Published: May 2020

Background: Celiac disease (CD) is a chronic, systemic immune disorder that can affect one’s quality of life. Objectives: The aim of this study was to explore the key performance indicators (KPIs) related to the quality of life of patients with CD admitted to the Celiac Association of Bouali Hospital in Zahedan. Methods: This descriptive-analytical study was performed on 60 patients with CD who referred to the Celiac Association of Bouali Hospital in Zahedan in 2018. Data collection tools included a demographic questionnaire (age, gender, marital status, duration of illness, education, ethnicity, economic status, occupation, breastfeeding history, family history of CD, as well as vitamin D and iron supplementation) and the Quality of Life Questionnaire for patients with CD. Data were analyzed in SPSS 21 using descriptive statistics. All values less than 0.05 were considered statistically significant. Results: Sixty participants completed the study, 66.7% of whom were female, 76.7% were married, and 85.3% reported a family history of CD. The total score of patients’ quality of life was 81.66 ± 18.33, and the lowest score of quality of life was associated with patients’ concerns (51.81 ± 3.85). The findings also showed that, among various KPIs, vitamin D had a particularly significant relationship with patients’ quality of life. Conclusions: There was a significant relationship between the quality of life and vitamin D supplementation in the participants. Besides, considering the effect of physical health on improving the quality of life and the chronic nature of CD, it is necessary to enhance the quality of life of these individuals by raising their awareness about micronutrient intakes while respecting their dietary restrictions.
New species of caddisflies with bipectinate antennae from Cretaceous Burmese amber (Insecta, Trichoptera: Odontoceratidae, Calamoceratidae)
Authors: Wichard Wilfried , Espeland Marianne , Müller Patrick , Wang Bo
Published: May 2020

Three new fossil species from Burmese amber are described, one clearly in family Calamoceratidae, the other two in the highly variable family Odontoceridae. The family Odontoceridae contains 18 disparate genera, but there are no good diagnostic characters, which makes it difficult to place fossil taxa in this family. We here offer a revised diagnosis for the family, highlighting the lack of good diagnostic characters, and the need to use sets of characters to place (extinct) taxa in this family. On this taxonomic basis we describe two new species in the hitherto monotypic fossil genus Palaeopsilotreta Wichard & Wang, 2017 (Odontoceridae), Palaeopsilotreta burmanica sp. nov. and P. cretacea sp. nov., redescribe the type species based on additional information, and describe features of the female, based on two specimens, one of which is embedded adjacent to a male identified as P. xiai. Males of Palaeopsilotreta bear bipectinate antennae; the antennae of the females are simple and filiform. Similarly, bipectinate antennae are present in the third species we describe, Bipectinata orientalis gen. et sp. nov., which otherwise lacks the character combinations associated with the Odontoceridae, but clearly can be assigned to the family Calamoceratidae.
El español de las telenovelas mexicanas
Authors: Grimm Anja
Published: May 2020

Las variedades en las clases de ELE / EL2 son un ingrediente indispensable y hay que recurrir a fuentes auténticas para ofrecer un input real a los alumnos. El uso de los recursos audiovisuales para tal efecto ya se ha normalizado en los últimos años, pero antes de usar las telenovelas mexicanas en el aula habría que determinar si el español hablado en las telenovelas mexicanas es realmente un reflejo de la(s) variedad(es) mexicana(s). En este artículo se investigan las características lingüísticas de nueve telenovelas mexicanas y se busca dar respuesta a la pregunta de si pueden constituir un input valioso tanto como variedad preferente o variedad periférica.
Propiedades psicométricas de los cuestionarios Reactive/Proactive Questionnaire (RPQ) y How I Think Questionaire (HIT) en estudiantes peruanos
Authors: Rojas Zegarra María Elena , Arias Gallegos Walter Lizandro , Rivera Renzo , Geldres García Jenny Adelí , Starke Moscoso Marlene Alejandra , Apaza Bejarano Evert Nazaret
Published: May 2020

Abstract: The present study aimed to value the relationships between reactive/proactive aggression and cognitive distortion among adolescents from Arequipa City in Peru, for which it was necessary to realize a psychometric analysis of the tests used.  Evaluated were 2,830 high school students (48.9% female and 51.1% male) aged between 13 and 19 years old, with the Reactive/Proactive Aggression Questionnaire and the How I Think Questionnaire. A psychometric analysis was performed to evaluate  the validity and reliability of the instruments applied, as well as a correlation analysis to determine the relation between the variables. The psychometric results show a construct validity and reliability of the questionnaires, with adequate fit values and internal consistency; while the correlation analysis reveals that the reactive aggression is weakly related with cognitive distortions, and proactive aggression is moderately related to cognitive distortions. Propiedades psicométricas de los cuestionarios Reactive/Proactive Questionnaire (RPQ) y How I Think Questionaire (HIT) en estudiantes peruanos Key words: Reactive aggression; proactive aggression; cognitive distortion; psychometrics.Resumen: La presente investigación tiene por finalidad valorar las relaciones entre la agresión reactiva/proactiva y las distorsiones cognitivas de adolescentes de la ciudad de Arequipa (Perú), para ello ha sido necesario realizar un análisis psicométrico de los instrumentos utilizados. En ese sentido se evaluó a 2830 estudiantes nivel secundario (48.9% mujeres y 51.1% varones) entre 13 y 19 años de edad, a través del Cuestionario de Agresión Reactiva/Proactiva y el Cuestionario How I Think. Se realizó un procesamiento psicométrico para valorar la validez y la confiabilidad de los instrumentos, así como un análisis de correlación para determinar el grado de relación entre las variables. Los resultados psicométricos dan cuenta de la validez de constructo y la confiabilidad de los instrumentos, que tienen índices adecuados de ajuste y consistencia interna; mientras que el análisis de correlación reveló que la agresión reactiva se relaciona de manera débil con las distorsiones cognitivas, y la agresión proactiva se relaciona de manera moderada con las distorsiones cognitivas.
Where Soutine Started His Journey
Authors: Širkaitė Jolanta
Published: May 2020

The article presents the first years of Chaïm Soutine, the remarkable artist of the École de Paris. The reconstruction of the facts of his life in Smilavichy and the years of art education in Minsk and Vilnius is based on the bibliography about the artist and the recollections of the artists who were close to Soutine in his youth.
Mané-Katz: Jewishness and Modernity
Authors: Reingold Svetlana
Published: May 2020

This article introduces Emmanuel Mané-Katz (1894–1962), a Jewish artist from Ukraine, who spent most of his life in Paris. The article discusses the problem of Judaism in art, how this problem was seen by the artists belonging to the Jewish School of Paris, and the relationship between Judaism and modernity in art, including Mané-Katz’s work.
A educação ambiental e o novo conceito de fake green
Authors: Fonseca da Silva Andé Ricardo , Cordeiro Alves André Luiz
Published: May 2020

O presente trabalho apresenta uma análise da crise ambiental atual, com enfoque na importância da construção de uma racionalidade ambiental, baseada no pensamento de Enrique Leff Zimmerman, Doutor em Economia do Desenvolvimento, que defende a transdisciplinaridade para construção epistemológica ambiental capaz de criar uma gestão verdadeiramente sustentável dos recursos naturais. A metodologia adotada foi à pesquisa qualitativa. Utilizou-se também o método de abordagem dedutivo, partindo-se de temas gerais, como meio ambiente e sustentabilidade. Já no que diz respeito à técnica da pesquisa, foi empregado o procedimento técnico de pesquisa bibliográfica. E concluiu-se pela relativização do conceito de Desenvolvimento Sustentável, criando uma antítese a esse termo: o Fake Green, que aborda os malefícios silenciosos gerados pela precariedade desse modelo incompatível com realidade atual de degradação ao meio ambiente, num cenário forjado, retroalimentando um sistema produtivo predatório; tendo como resultado, um percentual ínfimo de contratos com a administração pública que adotam critérios de sustentabilidade e, na esfera privada, a perpetuação de relatórios ambientais de grandes empresas que estão em desacordo com a realidade do impacto ambiental em toda sua cadeia produtiva; sendo a educação ambiental o único instrumento eficaz para o combate ao Fake Green.
Suprema Corte limitadora ou efetivadora do princípio da livre iniciativa? Uma análise de conteúdo das decisões do STF
Authors: Fróes Couto Pablo Florentino , Maumann Ximenes Julia
Published: May 2020

A pesquisa empírica do Direito realizada utiliza a análise de conteúdo de Bardin (2009) examinando as decisões do Supremo Tribunal Federal nos períodos de 2014 até 2018. Ela parte de uma análise quantitativa e qualitativa que visa responder se no quadriênio (2014 – 2018) a Corte Suprema vem limitando ou efetivando o princípio da livre iniciativa. Assim, o objetivo é inferir o significado de livre iniciativa utilizado pelo STF no contexto da tensão entre ordem econômica e ordem social do texto constitucional de 1988. Os resultados apontaram para um tribunal efetivador do princípio em questão. Em outras palavras, o STF durante o período analisado tem um perfil econômico liberalizante, rejeitando, portanto, o dirigismo estatal, que foi uma característica típica dos países socialistas adeptos da economia planificada.
Economic assumptions of the Ecological State: looking for sustainability
Authors: Câmara Ana Stela
Published: May 2020

Although many efforts were taken until now, the fact is that environmental questions are still challenging governments and civil society, what is evidenced by the continuous tendency of pollution´s growth, depletion of resources and loss of biodiversity. Considering that considering that anthropocentric conduct, reflected particularly by capitalism, as economic system, and industrialism, as production method, would have led to this disastrous and generalized level of environmental degradation, Klaus Bosselmann has purposed the Ecological State, a theoric model of State (re)organization, ethically based on ecocentrism. The present work intends to introduce the economic assumptions of the Ecological State, to understand in which way it can contribute to improve the notion of strong sustainability. The study points out that economic modern standards, seen as dogmas, are a difficult obstacle to changes and brings some of Tim Jackson´s purposes to reach prosperity without growth to a democratic transition to an Ecological State. The methodological approach is qualitative, pure and the main source of research is bibliographical.
El templo de Karnak – 4000 años de eternidad
Authors: Mateos Comaposada Marc
Published: May 2020

Este artículo explica el proyecto de reconstrucción mediante herramientas digitales del templo de Karnak, llevado a cabo por Marc Mateos, estudiante del GMMD. Mateos comenta las distintas fases de realización del proyecto hasta su presentación en 3D en el Museo Egipcio de Barcelona.
Epigenetic inheritance of circadian period in clonal cells
Authors: Li Yan , Shan Yongli , Kilaru Gokhul Krishna , Berto Stefano , Wang Guang-Zhong , Cox Kimberly H , Yoo Seung-Hee , Yang Shuzhang , Konopka Genevieve , Takahashi Joseph S
Published: May 2020

Circadian oscillations are generated via transcriptional-translational negative feedback loops. However, individual cells from fibroblast cell lines have heterogeneous rhythms, oscillating independently and with different period lengths. Here we showed that heterogeneity in circadian period is heritable and used a multi-omics approach to investigate underlying mechanisms. By examining large-scale phenotype-associated gene expression profiles in hundreds of mouse clonal cell lines, we identified and validated multiple novel candidate genes involved in circadian period determination in the absence of significant genomic variants. We also discovered differentially co-expressed gene networks that were functionally associated with period length. We further demonstrated that global differential DNA methylation bidirectionally regulated these same gene networks. Interestingly, we found that depletion of DNMT1 and DNMT3A had opposite effects on circadian period, suggesting non-redundant roles in circadian gene regulation. Together, our findings identify novel gene candidates involved in periodicity, and reveal DNA methylation as an important regulator of circadian periodicity.
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses
Authors: Wang Ling , Johnson Zachary Lee , Wasserman Michael R , Levring Jesper , Chen Jue , Liu Shixin
Published: May 2020

ATP-binding cassette (ABC) transporters are molecular pumps ubiquitous across all kingdoms of life. While their structures have been widely reported, the kinetics governing their transport cycles remain largely unexplored. Multidrug resistance protein 1 (MRP1) is an ABC exporter that extrudes a variety of chemotherapeutic agents and native substrates. Previously, the structures of MRP1 were determined in an inward-facing (IF) or outward-facing (OF) conformation. Here, we used single-molecule fluorescence spectroscopy to track the conformational changes of bovine MRP1 (bMRP1) in real time. We also determined the structure of bMRP1 under active turnover conditions. Our results show that substrate stimulates ATP hydrolysis by accelerating the IF-to-OF transition. The rate-limiting step of the transport cycle is the dissociation of the nucleotide-binding-domain dimer, while ATP hydrolysis per se does not reset MRP1 to the resting state. The combination of structural and kinetic data illustrates how different conformations of MRP1 are temporally linked and how substrate and ATP alter protein dynamics to achieve active transport.
The architecture of EMC reveals a path for membrane protein insertion
Authors: O'Donnell John P , Phillips Ben P , Yagita Yuichi , Juszkiewicz Szymon , Wagner Armin , Malinverni Duccio , Keenan Robert J , Miller Elizabeth A , Hegde Ramanujan S
Published: May 2020

Approximately 25% of eukaryotic genes code for integral membrane proteins that are assembled at the endoplasmic reticulum. An abundant and widely conserved multi-protein complex termed EMC has been implicated in membrane protein biogenesis, but its mechanism of action is poorly understood. Here, we define the composition and architecture of human EMC using biochemical assays, crystallography of individual subunits, site-specific photocrosslinking, and cryo-EM reconstruction. Our results suggest that EMC’s cytosolic domain contains a large, moderately hydrophobic vestibule that can bind a substrate’s transmembrane domain (TMD). The cytosolic vestibule leads into a lumenally-sealed, lipid-exposed intramembrane groove large enough to accommodate a single substrate TMD. A gap between the cytosolic vestibule and intramembrane groove provides a potential path for substrate egress from EMC. These findings suggest how EMC facilitates energy-independent membrane insertion of TMDs, explain why only short lumenal domains are translocated by EMC, and constrain models of EMC’s proposed chaperone function.
Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
Authors: Jung Sung Hoon , Oh Jung Hwan
Published: May 2020

Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a global pandemic and is now the most threatening public health issue. Patients with the infection present with high fever and pneumonia with respiratory symptoms, but some patients also develop digestive symptoms such as diarrhea, vomiting, and abdominal pain. This may be the basis for the transmission route of the new virus, not only for respiratory infection through droplets but also for fecal-to-oral transmission. In addition, the high expression level of angiotensin-converting enzyme 2 on the surface cells in the gastrointestinal tract may support the occurrence of digestive symptoms and the possibility of fecal-to-oral transmission. Recent studies have shown positive fecal polymerase chain reaction (PCR) test results in patients with the infection who showed digestive symptoms. Therefore, we reviewed the related literature on the occurrence of digestive symptoms in patients with COVID-19 and present the usefulness and clinical application of the fecal PCR test for identifying the potential infection route and criteria for isolation.
Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from México
Authors: Rodríguez-Pérez Elba G. , Arce-Mendoza Alma Y. , Saldívar-Palacios Roberto , Escandón-Vargas Kevin
Published: May 2020

Strongyloides stercoralis hyperinfection syndrome is a medical emergency that requires a high level of suspicion. Immunocompromised patients are at high risk of hyperinfection syndrome; however, malnutrition, alcoholism, and diabetes mellitus also need to be considered as predisposing factors. The diagnosis and treatment of Strongyloides hyperinfection are challenging and patients often have severe complications. Consequently, mortality is overwhelmingly high, with proportions above 60%.Herein, we report a case of Strongyloides hyperinfection in a 40-year-old alcoholic diabetic patient living in México. Unfortunately, the late diagnosis resulted in his death despite the treatment and supportive measures. Increased awareness is needed to prevent the dire consequences of strongyloidiasis.
A Study on Constraints Faced by Tribals in Availing Benefits from Different Tribal Development Schemes in Jammu and Kashmir State
Authors: Iqbal Tariq , Nanda Rakesh , Peshin Rajinder , Paswal Shazia
Published: May 2020

The study was conducted to find out the constraints faced by gujjars and bakerwals in availing the benefits of tribal developmental schemes in Jammu division of Jammu and Kashmir State. Multi-stage sampling technique was employed for the selection of districts, blocks, villages and ultimate respondents. The total sample size was 112. Pretested interview schedule was used for the collection of data. The major finding of the study revealed that lack of proper awareness followed by lack of knowledge of government intervention (66%), adequacy of funds (41%), High illiteracy rate among the respondents and living in the far-flung area are the major constraints which are faced by tribal in availing the benefits from Tribals developmental schemes.
Very Low Birthweight Infant's Placenta and Its Relation to Pregnancy and Fetal Characteristics
Authors: Hansen Anne R. , Collins Margaret H. , Genest David , Heller Debra , Schwarz Susan , Banagon Petra , Allred Elizabeth N. , Leviton Alan
Published: July 2002

Our objective was to relate pathology of the very low birthweight (VLBW) infant's placenta to pregnancy and fetal characteristics. We correlated the pathologic features of 1146 placentas from infants with birth weights of 500–1500 g who were born between 1/1/91 and 12/ 31/93 to the number of gestations per pregnancy, initiator of preterm delivery, gestational age, birth weight Z score, and duration of rupture of membrane (ROM). Placental correlates of acute inflammation and villous edema were associated with preterm labor (PTL), pre-labor premature rupture of membranes (PROM), lower gestational age, and higher birth weight Z score. In PTL pregnancies delivered within 1 h of membrane rupture, 61% of placentas already had membrane inflammation. Placental correlates of pregnancy-induced hypertension (PIH) were seen more commonly with PIH pregnancies, older gestational age, and lower birth weight Z score. We found a more prominent histopathologic signature for singleton than for multiple gestation placentas. The placental pathologic findings associated with the clinical diagnoses of infection, PIH, and low–birth weight Z scores in our VLBW/preterm population are similar to those in the literature regarding term pregnancies. The presence of multiple histologic findings consistent with inflammation in placentas of PTL pregnancies with duration of ROM lasting < 1 h suggests that some cases of PTL are precipitated by a more long-standing infection than that previously suspected. Morphologic placental features appear to be correlates of the phenomena leading to premature delivery. Examination of the VLBW infant's placenta provides insight into the etiology and management of VLBW/preterm deliveries.
One-month-old Infant with Multiple Ulcers of Stomach, Small Bowel, Large Bowel, and Protein-losing Enteropathy: Case Report
Authors: Stephen Thomas C. , Bendon Robert W.
Published: July 2002

Multiple inflammatory ulcers of the gastrointestinal tract are rare in young infants. Most cases are caused by infectious organisms, vasculitis, or an autoimmune process. We report a 1-month-old infant who was healthy until he presented with an inflammatory mesenteric cyst, and multiple ulcers of the stomach, duodenum, jejunum, ileum, and colon. Histologically, the ulcerations were sharply demarcated, full thickness, and filled with macrophages. He had a low serum albumin and IgG due to protein-losing enteropathy. He was treated with supportive care and immunomodulating drugs. The gastrointestinal inflammation resolved by 3 and 1/2 years of age. The medications were withdrawn at 5 and 1/2 years of age he had no relapse of clinical symptoms. He continues to have asymptomatic mild hypoalbuminemia and low serum IgG. We could not find a report of a similar clinical presentation and outcome.
Comparison of Immunohistochemistry and Silver Stain for the Diagnosis of Pediatric Helicobacter pylori Infection in Urease-negative Gastric Biopsies
Authors: Eshun John K. , Black Dennis D. , Casteel Helen B. , Horn Hazel , Beavers-May Toni , Jetton Christina A. , Parham David M.
Published: July 2002

We compared immunohistochemical and silver stains of pediatric gastric biopsy sections for the identification of Helicobacter pylori infection with chronic inflammation and a negative urease screening test. Thirty-seven patients (age range 10 months to 21 years) whose gastric antral biopsies were negative for the rapid urease test (CLOR) but positive for lymphocytic infiltration were selected for a retrospective study. Specimens had been subjected to a rapid urease test (CLOR) and hematoxylin and eosin staining, and Dieterle silver staining and immunohistochemical staining specific for H. pylori were also performed. Twelve additional patients with ureasepositive biopsies were used as controls. With Dieterle staining, 8/37 (22%) urease-negative biopsies contained organisms morphologically compatible with H. pylori, 21/37 (56%) contained organisms not compatible with H. pylori, and 8/37 (22%) were negative for organisms. Immunostaining confirmed 6/8 (75%) Dieterle-positive cases as being H. pylori, was negative in 2/8 (25%) Dieterle-positive cases, and was positive in 2/8 (25%) Dieterle-negative cases. Biopsies from 8/12 (67%) urease-positive specimens contained organisms seen with both Dieterle and immunohistochemical stains, and 4/12 (33%) were negative with both stains. Although both stains yielded comparable results with H. pylori–positive biopsies, Dieterle staining was potentially confusing because of nonspecific staining of other organisms. A significant proportion of (CLOR)-negative biopsies was positive for H. pylori with special stains. We therefore recommend the use of immunohistochemical staining rather than silver staining in the evaluation of urease-negative gastric biopsies demonstrating chronic inflammation in children.
Aggressive CD34-positive Fibrous Scalp Lesion of Childhood: Extrapulmonary Solitary Fibrous Tumor
Authors: Ramdial P.K. , Madaree A.
Published: July 2002

Although solitary fibrous tumor (SFT) was originally described as a pleural tumor, an increasing number of extrapleural sites of SFTs have been documented. This has been attributed not only to the heightened awareness of the spectrum of histopathological features that characterizes SFTs but also to the recognition of the role of CD34 immunostaining in soft tissue tumors in general, and in SFTs in particular. Despite the large number of documented extrapleural SFTs in adults, cranial SFTs are rare, having been documented in the meninges, scalp, and infratemporal fossa. Extrapleural SFTs are, to date, an unrecognized entity in children.

We document an aggressive fibrous scalp lesion in a 30-month-old female child that demonstrated features common to benign cranial fasciitis and SFT. However, based on bright, diffuse CD34 antigen immunopositivity, a diagnosis of SFT was made. The need to include the CD34 antigen stain in a panel of immunohistochemical markers used to assess spindle cell lesions of childhood is emphasized.