bluuebunny/crossref_metadata_2025 huggingface dataset:
Ekspektasi Pemangku Kepentingan dalam Rezim Kekayaan Intelektual yang Responsif
Authors: Darmawan Oksimana , Citrawan Harison , Apriansyah Nizar , Kurniawan Arief , Rini Nicken Sarwo , Salasa Amin , Analis Dewi
Published: February 2023

Kehadiran buku ini telah berhasil mengangkat keberadaan stakeholder KI di Indonesia karena rezim KI tidak saja keberadaan DJKI secara kelembagaan, terhadap pelindungan KI di Indonesia, namun stakeholders turut andil dan menjadi bagian dalam pengelolaan dan pengembangan rezim KI guna memperkuat pembangunan nasional dalam kerangka hukum responsif. Buku ini menjadi pengantar agar mendapatkan pemahaman bersama terhadap gap yang terjadi dari pemangku kepentingan KI di Indonesia dengan DJKI sebagai pelaksana Undang-Undang di bidang KI, yang ditujukan sebagai institusi yang responsif dalam pengelolaan KI, pada gilirannya dapat diterapkannya strategi yang lebih komprehensif dalam pengeloaan rezim KI nasional.
KESADARAN HUKUM PENGGUNAAN KOSMETIKA HALAL DIKALANGAN MAHASISWI FAKULTAS SYARIAH DAN HUKUM UINSU (STUDI FATWA MUI NOMOR 26 TAHUN 2013 TENTANG STANDAR KEHALALAN PRODUK KOSMETIKA DAN PENGGUNAANYA)
Authors: Hasibuan Nazlyany , Lubis Azwani , Firmansyah Heri
Published: February 2023

Setiap orang pasti memiliki alasan tersendiri dalam menggunakan produk kosmetika. Namun, sangat disayangkan dilapangan dalam praktek pemilihan produk kosmetik. khususnya dikalangan Mahasiswi FSH UINSU asal dalam memilih produk kosmetika, mereka lupa bahwa Fatwa MUI Nomor 26 Tahun 2013 telah mengatur tentang standart kehalalan produk kosmetika dan menggunaannya. Studi ini diarahkan pada metode penelitian hukum empiris, dan jenis penelitian ini adalah penelitian lapangan (Field Research), data diperoleh dari hasil wawancara, pengumpulan data dan dokumentasi. Dari penelitian ini ditemukan bahwa Mahasiswi dikalangan FSH dalam praktek pemilihan produk kosmetika belum memiliki kesadaran hukum yang cukup dalam memilih produk kosmetika halal, bahkan banyak dari mereka yang belum mengatahui bahwa ada Fatwa MUI yang mengatur tentang hal ini. Selain itu, beberapa tokoh MUI  Kota Medan sepakat mengatakan dalam praktek pemilihan produk kosmetika harus memperhatikan komposisi dan  bahan yang terkandung didalamnya, dan menjadikan produk yang bersertifikasi halal sebagai acuan dalam memilih produk kosmetika agar terhindar dari kemudharatan dan sesuai dengan syariat islam dan merasa lebih aman.Untuk itu perlulah untuk melakukan edukasi agar setiap masyarakat khususnya dikalangan mahasiswi fakultas Syariah dan hukum bisa sadar dan dengan keinginan dirinya sendiri untuk menggunakan produk kosmetika yang sudah bersertifikasi halal.
Implementation of Dynamic IP Blocking Techniques on the Tanungbalai City Library Website
Authors: Sirait Azrai , Siddik Muhammad
Published: February 2023

Website Tanjungbalai Library, is one of the most visited by people to find the necessary information, not only that, the website is also a place where people exchange ideas and share knowledge. The Tanjungbalai library website server currently does not have security, of course this will have an impact on the security of the existing data on the website, therefore to prevent unwanted things such as theft or hacking of the Tanjungbalai library website here researchers will take advantage of the features contained in cloud-based cpanel software. So that the security of the library's website server will be maximized, at this time there are still many weaknesses and shortcomings found on the library website, later IP visitors who try to damage will be blocked only by utilizing features on cloud-based cpanel. Information that is less tested and accurate will certainly be very disturbing in the decision-making process and in making reports.
Online Library Management App Madrasah Aliyah Negeri Binjai
Authors: Azura Zahra , Samsudin Samsudin , Ikhwan Ali
Published: February 2023

Technological changes to date are growing increasingly rapidly in various fields of life both in the field of health, the field of government, especially in the field of education. The world of education can also undeniably have a rapid impact on the development of technology, one of which is the means of school learning, namely the library. The library provides a platform for every student and student to develop their knowledge insight with various types of books. The use of technology to make library applications is needed in schools. This library application is made web-based and online, in this application will also be made sms reminder so that students are not late in returning books. This will greatly facilitate and speed up the performance of library officers who previously still use ledger records. So with the system that researchers designed at the Madrasah Aliyah State Binjai library can make library officers work more effectively and efficiently
Multi-Criteria Decision Making Using Additive Ratio Assessment in Digital Voice Recorder Selection System
Authors: Nugroho Nurhasan
Published: February 2023

Digital Voice Recorder has many uses, usually used for interviews, recording voices and songs, recording meeting results, and can be used for learning. Currently, various Digital Voice Recorder products have been circulating and have different functions and specifications that are created according to the needs of users. For this reason, users must be observant in choosing a Digital Voice Recorder to support their work. So, we need a system that can provide recommendations and help in making decisions to choose the right Digital Voice Recorder. This study aims to develop a decision support system with Multiple Criteria Decision Making (MCDM) using Additive Ratio Assessment (ARAS) to assist in selecting a Digital Voice Recorder, so that it can assist in selecting the best solution appropriately and according to user needs. The ARAS method is used as a model that can select the best alternative based on the utility level of each alternative to determine the best alternative. Based on the case studies conducted, the utility values of each alternative were obtained, namely: Zoom Handy Recorder with a value of 0.5672, Sony PX470 with a value of 0.6147, Ruizu X52 with a value of 0.4664 and Tascam DR-22ML with a value of 0.9096. So, the best alternative is the Tascam DR-22ML. Based on testing through the black-box testing method, it shows that the system built has been running well
LUNAR REGOLITH SIMULATION AT MICROWAVES
Authors:   Space Research Institute of Russian Academy of Sciences  119317, Russia, Moscow, Profsoyuznaya str. 84/32, Skulachev D.P. , Kosov A.S. ,   Space Research Institute of Russian Academy of Sciences  119317, Russia, Moscow, Profsoyuznaya str. 84/32
Published: February 2023

А remote measurement of the lunar regolith temperature from a lander is expected in the near future. A special bench for experimental testing of the experiment details has been created. The test bench simulates the measurement of the temperature of the lunar regolith at depths down to 1 m. The design features and thermal characteristics of the device are considered. The simulator operates at normal atmospheric pressure and provides a temperature drop from 20 to 100 Celsius in a meter-long regolith layer. It is planned to create a test bench that provides operation in a vacuum and a temperature drop from minus 150 to minus 30 Celsius.
ALGORITHM FOR DEVELOPING THE PROGRAM OF CURVED SURFACES BURN-IN
Authors: Volchenkov Aleksey , Nikitina Lyubov'
Published: February 2023

The results of differential geometric modeling and laboratory studies of the burn-in of hardened materials for complex sculpted surfaces are presented. The criteria of high-performance burn-in are given. It is shown that for complex sculpted surfaces, the instantaneous wear rate can be considered in terms of the wear rate, which determines the intensity of removing wear particles during the burn-in of the part in accordance with the selected method. Another criterion for the burn-in productivity is the instantaneous wear rate. The obtained dependences allow improving the modes of technological burn-in of part materials according to the criterion of its productivity. Laboratory verification of the obtained modes makes it possible to formulate criteria conditions for highly efficient burn-in of hardened curved surfaces.
FEATURES OF USING MULTIAXIS CNC GRINDING MACHINES TO IMPROVE MACHINING PERFORMANCE, QUALITY AND ACCURACYOF PARTS AND ASSEMBLIES OF AVIATION GAS TURBINE ENGINES
Authors: Makarov Vladimir , Pesin Mihail , Norin Aleksandr
Published: February 2023

The paper is aimed at improving the productivity, quality and accuracy of manufacturing gas turbine engine parts and assemblies for the modern growing passenger aviation transport based on the use of technical capabilities of modern multiaxis CNC grinding machining centers. The paper shows the results of successful application of a five-axis CNC grinding machining center MFP-050.65.65 made by Magerle (Switzerland), which allows reducing by five times the number of operations, universal machines, special devices and cutting tools by increasing the number of machined surfaces for one set of nozzle blades of an aviation gas turbine engine. Simultaneously with a significant increase in the productivity of machining various multidirectional surfaces of the nozzle blades due to the use of new highly porous grinding wheels and rational modes of deep grinding, a higher burn-free quality of the ground surfaces is ensured and an important task is solved to increase the accuracy of the flow sections of the turbine nozzle apparatus with the combined use of CNC system and special software for correcting errors of part casting surfaces during their installation, turning and deep grinding of the base surfaces. The developed new technology of nozzle blades machining was introduced for the first time in the Russian Federation at the Aviadvigatel enterprise for manufacturing nozzle blades of modern newly produced gas turbine engines.
CONSTRUCTION OF PIPELINE STOP VALVES USING THE LAWS OF HYDROSTATICS AND HYDRODYNAMICS
Authors: Kramsakov Damir , Chudinov Aleksandr , Kol'ga Anatoliy , Stolpovskich Ivan , Aleksandrov Viktor
Published: February 2023

Study objective. Giving grounds to the possibility of making pipeline stop valves with minimal mass and size parameters and maximum operational efficiency.

The task to which the paper is devoted. Reduction of mass and size parameters of pipeline stop valves.

Research methods. The problems are solved according to the basic methods of hydrostatics (Pascal's law) and hydrodynamics (Bernoulli’s principle).

The novelty of the work. It consists in finding the possibility of replacing complex, large-sized and massive elements of pipeline control systems with simple elements operating according to the basic laws of hydraulics.

Study results. The studies conducted confirm the possibility to simplify significantly the designs of pipeline stop valves, reducing the mass and size parameters and increasing the efficiency and reliability of pipeline systems.

Conclusions. Taking into account the peculiarities of the static and dynamic state of the fluid (liquid, gas), using the laws of hydrostatics and hydrodynamics, it is advisable to divide the entire structure of the pipeline stop valves into two interconnected devise components combined in one case: a device that locks the pipeline (stopping the fluid flow), and a device that opens the pipeline (ensuring the fluid flow). At the same time, one of the devices operates due to high-speed (dynamic) fluid pressure, and the second - due to static pressure.
MATHEMATICAL MODELING OF TURBULENT VISCOUS LIQUID MODE WITH CONTINUOUS FLOW RATE CHANGE FOR HYDRAULIC SYSTEMS
Authors: Ismailova Shahla Hajibala gizi
Published: February 2023

The current state of the issue related to the flow of two-phase (heterogeneous) liquids in hydraulic and water management systems is analysed. The paper objective is to develop hydrodynamic equations of infinitely variable two-phase fluids in accordance with mathematical models taking into account external mass exchange. Based on the problems defined in accordance with the paper objective, the task of building a mathematical model to analyze the turbulent mode of viscous fluid with a continuous flow rate change for hydraulic systems is set.
MODELING OF THE TEMPERATURE DISTRIBUTION ON THE LATHE FRONT SURFACE TAKING INTO ACCOUNT GEOMETRIC PARAMETERS OF THE SECONDARY PLASTIC ZONE
Authors: Fominov Evgeny , Marchenko Andrey , Suhomlinova Viktoriya , Pyatnickaya Oksana , Gladkih Dmitriy
Published: February 2023

The study objective: modeling of the temperature distribution along the front surface of the lathe cutter for a given moment of the cutting system evolution.

The problem to which the paper is devoted. To evaluate the influence of the geometric parameters of the secondary plastic zone of on the characteristics of the temperature distribution for the front surface of the lathe cutter.

Research methods. Geometric parameters of the plastically deformed layer are defined by digital modeling of contact processes by the finite element method. Some initial data for computer modeling and subsequent verification of its results are carried out on the basis of a full-scale experiment with longitudinal turning of a work piece made of stainless steel 12X18H9T with a T15K6 solid-alloy plate.

The novelty of the work. Prediction of the temperature on the cutter front surface for a given moment of the cutting system evolution based on a scientific approach of using hydrodynamic analogies to the evaluation of deformation processes in the machined material and combined data of a full-scale and digital experiment.

The study results. By means of a digital experiment, the boundaries of the secondary plastic zone in the chip are determined, then a temperature distribution curve is made on the cutter front surface in two variants: for variable and for a constant average thickness of the deformed layer. It is found that the average value of the contact temperature in both cases differs slightly and agrees well with the results of the full-scale experiment. The difference between the maximum temperature values is significant: with a variable layer thickness, the calculated temperature is 11% lower than for the variant with a constant value of this parameter.

Conclusions: to calculate the average temperature in the secondary plastic zone, the average value of the deformed layer thickness can be used. In the case of solving problems related to determining the maximum temperature in the cutting zone, it is advisable to take into account the change in the thickness of the plastically deformed layer in the chip along the cutter front surface.
METHODS FOR DETECTING LOCOTIVE SLIPPAGE
Authors: Kozhukhov Ivan , Boldyrev Aleksey , Lozbinev Fedor , Antipin Dmitriy
Published: February 2023

The study objective is giving grounds for the application of methods to increase the relative slip of the wheel pair along the rail with its insignificant amount. The main difficulty in using systems based on measuring the absolute or relative slip of the wheel on the rail is a small difference in the value of the speeds and the difficulty of determining the rail horizontal speed. The use of angular acceleration of rotating parts as a diagnostic parameter may also not yield results if the relative slip grows gradually. The novelty of the work is in a detailed analysis of slippage detection devices and evaluation of these approaches. As a result, it is concluded that in practice it makes sense to combine all three mentioned approaches to identify the slippage start on various grounds. To determine the wheel slid on the rail, it makes sense to use all the listed informative signs to reduce the number of false estimates of the slip start.
THE EXTENSION OF THE BRAKE CYLINDER ROD OF DIESEL LOCOMOTIVE LEVER TRANSMISSIONS
Authors: Sinicyn Vladimir , Gapchin Roman
Published: February 2023

The study objective is to develop a method for calculating the extension of the brake cylinder rod of a diesel locomotive. The extension value of the locomotive brake cylinder rod is currently not regulated, while the parameter is subject to control and must be consistent with the gaps between the brake shoe and the tyre. Its calculation involves taking into account the pressure in the cylinder, the cylinder diameter, the gear ratio of the lever transmission, the gaps between the shoe and the tyre, as well as the elastic deformation of the system. Currently, there is no method for determining the latter component, and this does not allow for a grounded choice of the brake cylinder at the design stage. In addition, increased wear of the brake shoes, for example, on a steep long descent, can lead to an insufficient rod extension. It is shown that significant exceedances of standard values are possible in operation. Thus, the extension of the brake cylinder rod of a diesel locomotive is an important parameter affecting traffic safety. The development of its calculation method is relevant.

It should be noted, that a significant contribution to the elastic component is made by wear-resistant bushings of lever transmission joints made of sintered iron-based materials. At the same time, the calculation of bushings is the most difficult.

A method including the calculation of elastic deformation of levers and rods, as well as wear-resistant bushings by solving the contact problem of radial axis insertion into the wall of the sleeve is chosen as a prototype for the method of calculating the elastic component of the rod extension. This method is refined taking into account the features of the lever transmission.

The calculation of the rod extension for the lever transmission of the main diesel locomotive bogie is performed. At the moment, experimental data on the elastic component of the rod extension are obtained for it, and it gives the opportunity to evaluate the calculation results. The calculation of the rod extension showed good compliance with experimental measurements. The method can be used to select the appropriate brake cylinders for the locomotive lever transmission.
Profitability as a Moderating Effect of Liquidity, Sales Growth and Leverage on Financial Distress in Islamic Commercial Banks
Authors: Ayu Virnanda Khofifah , Kartika Oktaviana Ulfi
Published: February 2023

Islamic commercial banks are inseparable from the risk of financial distress. Several financial ratios are able to predict Financial Distress. This study aims to determine the effect of Liquidity, Sales Growth, and Leverage on Financial Distress which is moderated by Profitability. The type of data used is panel data so that it uses panel data regression analysis assisted by Eviews 10 software. The moderation variable test uses Moderating Regression Analysis (MRA). Data collection used a purposive sampling method so as to obtain a sample of 13 Islamic commercial banks in the 2014-2020 period. This study uses the Random Effect Model (REM) technique to see the effect of the relationship between liquidity, sales growth, and leverage variables on financial distress variables simultaneously or partially. The results show that the variables of liquidity and leverage have a significant effect on financial distress. While the sales growth variable has no significant effect on financial distress. Variables that can be moderated by profitability are sales growth and leverage, but profitability is unable to moderate the relationship between liquidity and financial distress.

Keywords: Islamic commercial banks, Liquidity, Sales Growth, Leverage, Financial Distress
The agricultural mechanization situation of agricultural enterprises involved in organic and conventional hazelnut cultivation in Turkiye
Authors: KAHRAMAN Onur , ALTUNTAŞ Ebubekir , GÖKDOĞAN Osman
Published: February 2023

The aim of the research is to examine and evaluate the agricultural mechanization status of organic and traditional hazelnut farming enterprises in Alaplı and Karadeniz Ereğli districts of Zonguldak province in Turkey. A survey was conducted with a total of 209 enterprises from 34 villages in 2 districts where hazelnut production is intense in the research. The survey study includes information about the land assets of the enterprises, tractor, agricultural-tool and machinery assets, and hazelnut production stages. In addition, mechanization applications in all agricultural processes from tillage to harvest in hazelnut production were examined and evaluated. It has been determined that 24 of the organic hazelnut production enterprises and 30 of the traditional hazelnut production enterprises have tractors and it has been determined that the tractor brand preferences of the enterprises vary independently from each other. Massey Ferguson and New Holland brands are mostly preferred. It has been determined that the vast majority of businesses prefer to use motorized hoeing machines. As a result, when organic hazelnut enterprises used traditional hazelnut production in previous years and gave up this production system, they reduced the use of tools and machinery. For this reason, it has been determined that there are fewer tools and machines in organic hazelnut producer enterprises compared to traditional hazelnut producer enterprises. While the tractor power (kW/ha) value per unit area processed in organic hazelnut producer enterprises was 1.344, this value was found as 6.320 kW/ha in traditional hazelnut producer enterprises. It is seen that traditional hazelnut producer enterprises are in a better situation in terms of mechanization level than organic hazelnut producer enterprises.
Evaluation of maize farmers’ attitude towards risk management and preference for crop insurance in Nigeria
Authors: ALABI Olugbenga Omotayo , MAKARAU Sheu Bako , ALUWONG Jeremiah , BAYEİ Joseph , LYOCKS Jummai Sunday , MAN Abdullahı , DRİSU Tijani , ANEKWE Chinwe Edith , SAFUGHA Godbless Friday , ALABUJA Funso , OBİNNA- NWANDİKOM Cynthia Onyinyechi
Published: February 2023

This study focused on evaluation of maize farmers’ attitude towards risk management and preference for crop insurance in Nigeria. Multi-stage method of sampling was used. One hundred (100) maize producers were sampled and selected. Primary sources of data were used for this study and the data were collected through the use of well-structured and well-designed questionnaire. Econometrics and statistical tools employed were used for data analysis. The results obtained show that 51% of maize farmers were risk averse, 21% were risk preferring, and 28% were risk neutral. Age, gender, and education level were statistically and significant predictors influencing risk averse attitudes of maize farmers. Age, farm size, household size, gender, risk aversion, education level, and access to agricultural extension services were the statistically and significant predictors influencing preference of maize farmers for crop insurance policy. Garrett index ranking technique employed for risk management strategies and crop insurance policy adopted by maize farmers show that crop diversification was ranked 1st, weather information was ranked 2nd, crop insurance was ranked 3rd, and off-farm activities was ranked 4th respectively. The results of constraints faced by maize producers revealed that lack of extension services was ranked 1st, lack of credit facilities was ranked 2nd, inadequate knowledge of agricultural insurance was ranked 3rd, high premium of agricultural insurance was ranked 4th, while lack of fertilizer was ranked 5th respectively. The constraints retained explained 74.85% of all constraints in the analysis. The study recommends that extension officers should be employed to disseminate research results, innovations and information on risk management strategies and crop insurance to maize farmers. Weather information should be made available to maize farmers, and credit facilities at low interest rate should be provided to maize farmers. Bureaucratic process and cumbersome administrative procedures in accessing credit facilities should be removed.
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Authors: Er Er , Arbic Given arabic
Published: February 2023

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Authors: Penulis
Published: February 2023

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Molecular hydrodynamic theory of the velocity autocorrelation function
Authors: Seyler Sean Lee , Seyler Charles E
Published: February 2023

The velocity autocorrelation function (VACF) encapsulates extensive information about a fluid’s molecular-structural and hydrodynamic properties. We address the following fundamental question: How well can a purely hydrodynamic description recover the molecular features of a fluid as exhibited by the VACF? To this end, we formulate a bona fide hydrodynamic theory of the tagged-particle VACF for simple fluids. Our approach is distinguished from previous efforts in two key ways: collective hydrodynamic modes are modeled by linear hydrodynamic equations; the fluid’s static kinetic energy spectrum is identified as a necessary initial condition for the momentum current correlation. Our formulation leads to a natural physical interpretation of the hydrodynamic VACF as a superposition of quasinormal hydrodynamic modes weighted commensurately with the static kinetic energy spectrum, which appears to be essential to bridging continuum hydrodynamical behavior and discrete-particle kinetics. Our methodology yields VACF calculations quantitatively on par with existing approaches for liquid noble gases and alkali metals; moreover, our hydrodynamic model for the self-intermediate scattering function extends the applicable domain to low densities where the Schmidt number is of order unity, enabling calculations for gases and supercritical fluids.
Management Of Mental Nursing Care Among Schizophrenia Patients With Social Isolation Problems: Case Study
Authors: Tanjung Ika Namira , Pardede Jek Amidos
Published: February 2023

The problem that often occurs in schizophrenic patients is social isolation. Schizophrenia is a psychotic disorder characterized by major disturbances in thought, emotion, and behavior, disturbed thinking, in which various thoughts are not logically related, erroneous perception and attention, flat or inappropriate affect, and various odd motor activity disturbances. Poor social skills are closely related to disease recurrence and patient return to the hospital. Social isolation is a condition in which individuals experience a decline or are even completely unable to interact with other people around them. Social isolation is a condition in which individuals experience a decline or are even completely unable to interact with other people around them. because schizophrenic patients lose their identity and experience role and function failure in interacting with society. This writing method is done by studying the problem of patient care. Collecting data using interviews and observation. Data collection tools or instruments use the assessment format. The subject to be used is one patient with social isolation in the cempaka room. The client's medical diagnosis is paranoid schizophrenia. With diagnoses including social isolation, hallucinations, and low self-esteem. The results of the analysis show that interventions with implementation strategies (SP) can reduce signs and symptoms of social symptoms in patients after being given an intervention even though it requires a gradual process, but does not experience drastic changes that can slowly improve the ability to socialize with other people.
Differential expression of AMIGO2 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding adhesion molecule with Ig-like domain 2, AMIGO2, when comparing pancreatic tumors to the tissue of origin, the pancreas. AMIGO2 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of AMIGO2 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. AMIGO2 expression changes may be important for the initiation or progression of human PDAC.
Differential expression of MST1R in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding macrophage stimulating 1 receptor, MST1R, when comparing pancreatic tumors to the tissue of origin, the pancreas. MST1R mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of MST1R in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. MST1R expression changes may be important for the initiation or progression of human PDAC.
Differential expression of CTSE in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding cathepsin E, CTSE, when comparing pancreatic tumors to the tissue of origin, the pancreas. CTSE mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of CTSE in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. CTSE expression changes may be important for the initiation or progression of human PDAC.
Differential expression of TRIM16 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding tripartite motif-containing 16, TRIM16, when comparing pancreatic tumors to the tissue of origin, the pancreas. TRIM16 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of TRIM16 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. TRIM16 expression changes may be important for the initiation or progression of human PDAC.
Berkenalan Singkat Dengan IoT
Authors: Irianto Kurniawan D.
Published: February 2023

IoT (ed. dibaca ‘ai o ti’) adalah singkatan dari Internet of Things di mana IoT merupakan sebuah jaringan yang menghubungkan objek-objek (Things) tertentu. Perangkat IoT juga biasanya sudah teintegrasi dengan sensor-sensor, perangkat lunak, dan teknologi lainnya yang berfungsi untuk menghubungkan dan saling bertukar informasi antara perangkat IoT dengan sistem-sistem menggunakan jaringan internet. Jenis perangkat IoT tersebut sangat banyak dan bervariasi, mulai dari perangkat yang ada di rumah tangga hingga perangkat khusus yang digunakan di industri. Pada tahun 2020, jumlah perangkat IoT di dunia yang terkoneksi ke internet adalah sekitar 10 milyar. Jumlah ini diperkirakan akan terus bertambah dan diprediksi akan berjumlah sekitar 100 milyar pada tahun 2030.
Disparate parasocial phenomena evaluation in traditional media and immersive virtual reality
Authors: Straight Ryan
Published: February 2023

As media types and platforms proliferate, viewers and users continue to build relationships with performers and personas. These distant and uni-directional experiences–known as “parasocial interactions” (PSIs) and “parasocial relationships” (PSRs)–have changed, as well. While research into immersive virtual experiences has shown to positively develop these parasocial phenomena, less is known about how and where these differences occur. This study compared similar traditional media (YouTube) and immersive media (virtual reality via head-mounted display) using existing parasocial evaluatory instruments. Findings confirm statistical differences between the two platforms and between instruments applied within platforms, suggesting a re-evaluation of the tools when exploring platform-specific parasocial phenomena, especially in immersive virtual environments.
BMF Collaborative Project 16: Belief about AI's mind and self-prolongation
Authors: Team AISDL
Published: February 2023

BMF Collaborative Project 16: Belief about AI's mind and self-prolongation
Application of Generalist Therapy in Providing Mental Nursing Care Among Schizophrenic Patients with Violent Behavior Risk Problems: A Case Study
Authors: Nazara Ristiniati , Pardede Jek Amidos
Published: February 2023

Schizophrenia is a psychiatric disorder experienced by someone who can affect behavior which is characterized by confused thoughts, irritability, tend to withdraw, difficulty sleeping and irritability. One of the symptoms of schizophrenia is the risk of violent behavior. The risk of violent behavior is an angry response expressed by making threats, injuring oneself or others and can damage the surrounding environment. Signs and symptoms of risk of violent behavior can occur changes in cognitive, affective, physiological, behavioral and social functions. Treatment with a risk of violent behavior can be implemented with generalist therapy. Purpose: to provide psychiatric nursing care through generalist therapy to patients at risk for violent behavior. Method: this writing uses a case study approach to interviews and observation techniques. The subject in this case study was one patient with a risk of violent behavior in the Pusut Buhit Room at the Mental Hospital Prof. Dr. Muhammad Ildrem. Implementation was carried out on patients at risk of violent behavior for fifteen days. The results obtained after giving generalist therapy show that the patient is able to control the risk of violent behavior with physical exercise 1: deep breathing and physical exercise 2: hit the bed with pillows, the patient is able to take medication regularly, the patient is able to speak well, the patient is able to pray independently It is expected that nurses will always apply generalist therapy to patients with a risk of violent behavior.
Application of Mental Nursing Care Among Schizophrenic Patients with Hallucination Problems Through Generalist Therapy (Sp 1-4): Case Study
Authors: Panjaitan Yemima
Published: February 2023

Schizophrenia is a group of psychotic reactions that affect various areas of individual functioning, including thinking, communicating, feeling and expressing emotions as well as brain disorders characterized by disorganized thoughts, delusions, hallucinations and strange behavior. Auditory hallucinations experienced by the patient even affect the mind, where the patient is ordered to do something that is sometimes dangerous. The purpose of this writing is to provide mental nursing care to Mrs. I at RSJ PROF. Dr. M. ILDREM. The writing method is descriptive, namely a case study by carrying out nursing care for patients with auditory hallucination problems with a treatment implementation strategy (SP) carried out for 6 days on Ny. I. Data collection techniques were carried out using interview techniques, observation, and physical examination. The nursing problem found in Mrs.I's patients is auditory hallucinations. With 6 days of management, Mrs. I was able to rebuke the hallucinations. Suggestions in managing patients with sensory perception disorders: auditory hallucinations are expected. With this study, medical staff can build a trusting relationship with clients so that good communication can emerge and clients can express their problems so that the nursing process can be achieved, the role of the family is to visit clients and take care of them. clients who now live alone and provide adequate support and attention to clients to speed up the client's healing process.
MAZHAB-MAZHAB ANTROPOLOGI HUKUM
Authors: Rahmanda Viko M
Published: February 2023

Antropologi hukum itu adalah ilmu pengetahuan (logos) yang mempelajari tentang manusia (antropos) yang bersangkutan dengan hukum. Dalam hal ini, manusia yang dimaksud adalah manusia yang hidup bermasyarakat, berinteraksi dan bergaul antara yang satu dengan yang lainnya. Baik itu masyarakat yang budayanya masih sederhana, maupun masyarakat yang sudah maju atau modern budayanya. Sedangkan budaya yang dimaksud dalam hal ini adalah budaya hukum, yaitu bentuk perilaku manusia yang berkaitan dengan masalah hukum.Antropologi sebagai disiplin terus berkembang, tidak hanya pada tataran teoritis tetapi juga sebgai ilmu terapan yang mampu memberikan masukan bagi para pembuat keputusan dalam menentukan kebijakan pembangunan. Awal kelahiran antropologi hukum biasa berkaitan dengan karya klasik Sir Henry Meine yang bejudul “The Ancient Law”, yang secara ringkas menyatakan bahwa hukum berkembang seiring dan sejalan dengan perkembangan masyarakat, dari masyarakat yang sederhana (primitive), tradisional, kesukuan (tribal), ke masyarakat yang kompleks dan modern dan hukum yang inherent dengan masyarakat semula menekankan pada status kemudian wujudnya berkembang ke bentuk kontrak.
Involuntary Xenophobic Reflex Shows Entrenched Xenophobia In Western European Academia: The Swedish Case
Authors: Tulun Teoman Ertuğrul
Published: February 2023

A Swedish professor, has been accused of committing xenophobic acts towards a Turkish university student. This occurrence, at first glance, seems ostensibly an isolated example of a lack of tolerance and acceptance in academia. It is helpful to briefly recall the last elections in Sweden and the attitudes of various parties on issues that may be related to xenophobia and racism. The Sweden Democrats were the most successful party in the election. Common understanding assumes that the Swedish Democrats were created by Nazi sympathizers and have been marginalized for decades. Many individuals fear that there will be a new wave of right-wing parties either directly coming to power in Europe or affecting the government. This and other examples and messages of the government officials are shown of the new "paradigm shift". However, some argue that "paradigm shift" should not be exaggerated.
ANTROPOLOGI HUKUM SEBAGAI LANDASAN MANUSIA BERFIKIR SECARA DASAR
Authors: althoriq M.dzakwan , althoriq muhammad dzakwan
Published: February 2023

.Berpikir kritis atau critical thinking adalah suatu keharusan bagi setiap orang memilikinya. Dengan berpikir kritis, seseorang tidak terjebak jurang negatif dan kesalahan karena berpikir kritis adalah berpikir positif mencapai produk yang otentik dan jelas
Manajemen Asuhan Keperawatan Jiwa Pada Ny. N Dengan Masalah Halusinasi Melalui Strategi Pelaksanaan (SP 1-4)
Authors: Dachi Lewistin
Published: February 2023

Schizophrenia is a group of psychotic reactions that affect multiple areas of individual functioning, including thinking, communicating, feeling and expressing emotions, and a brain disorder characterized by disorganized thoughts, delusions, hallucinations and strange behavior. Schizophrenia is a severe chronic mental disorder characterized by communication difficulties, reality disturbances, abnormal or blunted affect, impaired cognitive function and difficulty in carrying out daily activities. Auditory hallucinations are a state where a person experiences a change in pattern or when the client hears clear or unclear voices where the voice usually invites the client to speak or do something but is not related to real things that cannot be heard by other people. The research method uses a case study approach. The subject used in this case study is one of the patients with sensory perception disorders: auditory hallucinations in Prof. Dr. Muhammad Ildrem Medan, Collecting data using interviews, observation and documentation studies. Obtained data on clients who experience sensory perception disorders: auditory hallucinations. The client's medical diagnosis is paranoid schizophrenia. With a diagnosis of auditory hallucinations, social isolation and low self-esteem. The results of the analysis show that engagement interventions by implementing implementation strategies (SP) can reduce signs and symptoms of auditory hallucinations in patients after being given the procedure.
Differential expression of PYGB in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding phosphorylase, glycogen; brain, PYGB, when comparing pancreatic tumors to the tissue of origin, the pancreas. PYGB mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of PYGB in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. PYGB expression changes may be important for the initiation or progression of human PDAC.
Tinjauan Umum Tentang Konstitusi dan Kedaulatan di Indonesia
Authors: setiawan Roni
Published: February 2023

Penelitian ini menggunakan metode studi kepustakaan (library research)Sebagai konsekuensi logis dari fakta bahwa tidak ada negara yang dapat dibentuk tanpa konstitusi, konstitusi memainkan peran yang sangat penting dalam kehidupan ketatanegaraan negara, seperti "perjalanan cinta Romeo dan Juliet yang setia dan abadi". Demikian pula negara dan konstitusi merupakan lembaga yang tidak dapat dipisahkan satu sama lain.
ANTROPOLOGI DAN HUKUM DALAM SATU ILMU
Authors: Marisa Selvi
Published: February 2023

Hukum dapat dilihat dari berbagai persepektif, pandangan yang dominan dan yang mendominasi hukum di Indonesia yakni pandangan positivistic . Hal ini tidak sejalan dengan hukum yang memiliki perspektif antropologis yang memberikan pemahaman terhadap masyarakat tertentu. Selain itu ilmu antropologi hukum adalah proses membelajari perilaku manusia dengan sagala aspek terkait dengan norma hukum yang berlaku dapat berbentuk tertulis maupun tidak tertulis. Sehingga antropologi hukum merupakan bagian dari kebudayaan serta nerupakan bagian dari budaya hukum.
Differential expression of STYK1 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding serine/threonine/tyrosine kinase 1, STYK1, when comparing pancreatic tumors to the tissue of origin, the pancreas. STYK1 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of STYK1 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. STYK1 expression changes may be important for the initiation or progression of human PDAC.
Differential expression of FGD6 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding FYVE, RhoGEF and PH domain-containing 6, FGD6, when comparing pancreatic tumors to the tissue of origin, the pancreas. FGD6 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of FGD6 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. FGD6 expression changes may be important for the initiation or progression of human PDAC.
Differential expression of EFNA5 in pancreatic cancer.
Authors: Mamoor Shahan
Published: February 2023

Cancer is a leading cause of death and pancreatic cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with pancreatic cancer, pancreatic adenocarcinoma (PDAC). We found significant differential expression of the gene encoding ephrin A5, EFNA5, when comparing pancreatic tumors to the tissue of origin, the pancreas. EFNA5 mRNA was present at significantly higher quantities in tumors of the pancreas as compared to normal pancreatic tissue. Analysis of human survival data revealed that expression of EFNA5 in pancreatic tumors was correlated with overall survival in patients with pancreatic adenocarcinoma. EFNA5 expression changes may be important for the initiation or progression of human PDAC.
Aging and age-related diseases
Authors: Zhang Xiaoxiao , Ouyang Jess Lan , Tang Man , Fu Min , Peng Jingli , Liu Qiuyun
Published: February 2023

Various mechanisms have been proposed, and a molecular perspective is much awaited to account for the observed phenomena regarding aging and death. Valine and glycine are overrepresented in numerous causative factors of heart disease and Alzheimer’s disease, as well as in proteins of SARS-CoV-2 strains causing the current pandemic. Both amino acids have long carbonyl bond lengths and thus possess affinities to divalent cations, promoting the formation of insoluble salts. The insoluble and stiff calcium oxalate is stressful to cells and triggers cell senescence. Consequently valine plus glycine content can serve as a ticking aging clock as longevity genes generally encode proteins rich in valine plus glycine. Given the common characteristics of the longevity gene products, aging process may be intervened by diet, exercise and lifestyle.