bluuebunny/crossref_metadata_2025 huggingface dataset:
miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphoma
Authors: Kawaji-Kanayama Yuka , Tsukamoto Taku , Nakano Masakazu , Tokuda Yuichi , Nagata Hiroaki , Mizuhara Kentaro , Katsuragawa-Taminishi Yoko , Isa Reiko , Fujino Takahiro , Kimoto-Matsumura Yayoi , Mizutani Shinsuke , Shimura Yuji , Taniwaki Masafumi , Tashiro Kei , Kuroda Junya
Published: January 2023

B-cell receptor (BCR) signaling is critically activated and targetable for mantle cell lymphoma (MCL); however, the underlying mechanism of the activated BCR signaling pathway is not clear. The pathogenic basis of miR-17-92 cluster remains unclear although the oncogenic microRNA (miRNA) miR-17-92 cluster is highly expressed in patients with MCL. This study revealed that miR-17-92 cluster overexpression is partly dependent on SOX11 expression and chromatin acetylation of MIR17HG enhancer regions. Moreover, miR-17-92 cluster regulates not only cell proliferation but BCR signaling activation in MCL cell lines. Pulldown-seq, where mRNA was captured using biotinylated miRNA transfection, was performed and analyzed with next-generation sequencing. Additionally, novel miRNA targets, including tumor suppressors such as BTG2, were identified to comprehensively define miR-17-92 cluster targets. Notably, gene expression profile data of patients with MCL revealed that BTG2 expression was negatively associated with those of BCR signature genes. Moreover, BTG2 silencing in MCL cell lines significantly induced BCR signaling overactivation. Our results suggest an oncogenic role of miR-17-92 cluster-activating BCR signaling throughout BTG2 deregulation in MCL.
Synthesis, Crystal structure, in vitro, and in silico biological studies of 2, 5-dihydroxybenzaldehyde based novel Schiff bases
Authors: todarwal minakshee , Sancheti Rakesh S. , Shah Hakikulla H. , Patil Arvind M. , Patil Rahul D. , Bendre Ratnamala S.
Published: January 2023

The present study reports the synthesis of novel Schiff base ligands (S1-S8) derived from 2, 5-dihydroxybenzaldehyde by coupling with substituted amines. Further, the electron-donating and electron-withdrawing substituents on the amines are intended to tune the properties of the new Schiff base ligands. The chemical structures of these compounds were extensively elucidated by FT-IR,1H-NMR,13C-NMR, and ESI-MS. The X-ray analyses show that the compounds crystallized in a triclinic crystal system with a space group of P-1 and Z = 2 for S1. Besides, antimicrobial potency against gram-positive bacteria and gram-negative bacteria, as well as against fungi, was studied. S3has superior inhibitory activity against all bacterial strains. The consortium of different substituent atoms on the phenyl ring and the heterocyclic ring counterpart is one of the reasons behind the recorded optimal activity. Compound S8has potent antifungal inhibitory action againstC.albicanscompared to the standard antifungal, whereas Schiff base S5also has well to moderate activity against all fungal strains. A molecular docking result indicates that these compounds could also be effective against the resistance β-ketoacyl-ACP (acyl carrier protein) synthase-I enzyme ofE.coli.
Cuticular and glandular chemistry are correlated with ovary size in two populations of the facultatively social carpenter bee, Xylocopa sonorina
Authors: Saleh Nicholas W. , Ostwald Madeleine M. , Ramírez Santiago R.
Published: January 2023

Chemical communication plays a critical role in the organization of insect societies. Although the identity and function of chemical signals in eusocial species have been well-characterized, there is still relatively little understood about the role that chemical communication plays in insects with the simplest forms of social organization. Generally, it is hypothesized that the complex chemical signals of eusocial species evolved from existing fertility-linked chemical variation in solitary species, which then facilitated the formation of reproductive hierarchies as social complexity increased and the reproductive division of labor evolved. Here, we characterize the cuticular and Dufour’s gland chemistry of the facultatively social large carpenter bee, Xyolocopa sonorina, which can form small, fluid social groups that often consist of non-kin and assess whether chemistry is correlated with changes in reproductive status in two populations. We find that compounds from the cuticle and Dufour’s gland show strong correlations with ovary size in both populations. Overall, our results demonstrate that the cuticular and Dufour’s gland chemistry contains reproductive information that could be useful in mediating social interactions in small, simple insect societies.
Which One is Best? Household Solid Waste Collection Facility Siting in a Developing Countries’ Autonomous Region
Authors: Setiawan Eko , Kusuma Juang Victorio , Sulistyawan Ganang Adi , Astuti Septin Puji
Published: January 2023

In many developing countries, the regencies in them have a relatively high degree of autonomy one of which is related to rights to place capacitated waste collection facilities from which the waste is conveyed to final waste clearance facilities. The rights include the management of waste generated by the waste producers at some places yet, due to limited budget, do not touch the waste management at this lowest level at other places. Given the growing importance and emergence of waste-related issues, the paper deals with the problem of siting household solid waste collection facilities within the context of an autonomous region. A waste-weighted P-median, a pure P-median, a P-centre, a P-dispersion and a “distance gap” models are proposed for the problem. By using data obtained from Karanganyar Regency, the Republic of Indonesia, as a problem context, the paper concludes that the best model for the siting problem in such regions is driven by the objective of the siting itself. Moreover, the paper suggests that collection facilities with large capacities should be given a lot more attention in terms of having anticipation to the demand of household solid waste the regions will have in the future.
Minimal non-BFC-rings
Authors: ARTEMOVYCH Orest
Published: January 2023

We study associative rings in which every proper subring is BFC (i.e., has the center of finite index) and obtain a characterization of minimal non-BFC unitary rings of finite characteristic.
2010 Mathematics Subject Classification. 16L30, 20F24, 16N20, 17B60.
BERT-RCNN: an Automatic Classification of App Reviews using Transfer Learning based RCNN Deep Model
Authors: Kaur Kamaljit , Kaur Parminder
Published: January 2023

App reviews considered as the major concern over the internet. It influences the user’s mind before purchasing the app. However, such user reviews might contain technical information about the app that can be valuable for the developers and software companies. Due to pervasive use of mobile apps, large amount of data is created by users on daily basis. Manual identification and classification of such reviews is very time-consuming and laborious task. Hence, automating this process is essential for helping developers in managing these reviews efficiently. Recently, traditional machine learning and deep learning oriented approaches have been exploited for classification of app review into software requirements. Most of the machine learning techniques utilizes traditional word techniques to extract the features from the textual reviews. In addition, deep learning techniques with efficient word embedding technique also improve the classification performance of the model. However, it is found that these techniques suffer from polysemic problem. To address aforementioned problem, this research paper presents novel neural language based framework, BERT-RCNN to classify app reviews into specified categories of functional requirements such as Bug report, Feature Request and Relevant etc. The presented framework has two main modules: Bidirectional Encoder Representation for Transformer (BERT) module and Recurrent-Convolutional Neural Network (RCNN) module. BERT module extracts the contextual relationship between the textual reviews. Then, these features are input to RCNN module to capture more important features with deep semantic information. The output of RCNN is fed to fully connected layer for classification purpose. Extensive experiments are conducted on five datasets to investigate the effectiveness of the presented BERT-RCNN model. For evaluation purpose, standard performance measures are used to obtain the results. Moreover, hyperparameter such as BiLSTM memory unit, CNN filters and CNN kernel size are tuned to ensure the quality of prediction. Comparative analysis of proposed model is conducted with existing state-of-the-art models. It shows that BERT-RCNN outperforms other state-of-the-art models with respect to precision, recall, f-measure and accuracy.
Normal pressure hydrocephalus following cranial radiation: identification of shunting responders
Authors: Cayuela Nuria , Domínguez-Lizarbe Manuel , Plans Gerard , Alemany Montserrat , Sánchez Juan José , Andrés Begoña , Lucas Anna , Bruna Jordi , Simó Marta
Published: January 2023

Purpose
Normal pressure hydrocephalus (NPH) following cranial radiotherapy (RT) has a deleterious effect on patient’s daily functioning. However, there is no consensus on its management in cancer population. The aim of our study is to examine cognitive, brain MRI and lumbar infusion test (LIT) features and to identify predictors of response to ventricular shunting (VPS) in long-term cancer survivors.
Methods
Patients who completed cranial RT at least 2 years before, with clinically suspected NPH and an Evans’ index (EI) ≥ 0.30, undergo a cognitive and a cerebrospinal fluid (CSF) volumetric (MRI) analysis (n = 36). For those in whom VPS was placed (n = 14), we explore whether adding a CSF volumetric analysis to classical MRI and LIT (Tap Test) features would better identify VPS responders.
Results
Nearly 80% of our cohort exhibited cognitive impairment, especially focused on executive functioning. There were no differences regarding clinical, LIT or MRI classical features between those who improved or were not following VPS. In contrast, CSF volume at NPH diagnoses resulted significantly larger in the group of VPS responders (p = 0.04). The addition of CSF volume to NPH diagnoses increased accuracy to 93%, with a PPV of 91% and NPV of 100%, resulting in a predictive factor of response to VPS.
Conclusion
The addition of a quantitative MRI analysis of CSF volume to classical MRI and LIT NPH criteria, together with a high clinical suspicion of NPH in long-term survivors following cranial RT, may help to identify VPS responders, thus improving the clinical management and prognosis of this population.
A micro-econometric analysis of the determinants of Households Saving Behavior in Uganda- A Multinomial logit modelling approach
Authors: Ssebulime Kurayish , Sebukeera Hennery , Wasswa Francis
Published: January 2023

Households have a number of saving choices to make and each of their choices has profound implications for the economy and for their standards of living. To investigate the determinants of household choice of saving mechanism, the multinomial logit model is applied. The main conclusion of this paper is that, employment status, household size, household monthly expenditure, education level, age of the household head, residence of the household, and marital status are significant determinants of household saving behavior in Uganda. It is thus recommended that, policy measures for ensuring financial inclusion should take cognizant of the differences in socioeconomic household characteristics like residence of households with regard to rural and urban based households. Further, increasing the level of education is critical for enhancing financial knowledge and is critical for enhancing adoption of formal saving mechanisms. Targeted policy actions to enhance financial knowledge should be critical in enhancing financial inclusion.
JEL: D13; D14, D15
Early Functional Outcome of Proximal Femoral Nail Antirotation in Treatment of Unstable Intertrochanteric Fractures
Authors: Alssir Mohamed Ahmed , Elbadri Mohammed Elfatih , Fageer Mohamed Abdelgany Yousif , Hamad Mohammed Abdulal Mohammed Saied , Saeed Ali Awadallah
Published: January 2023

Background:
Fractures of the hip are common injuries. Approximately 50% of hip fractures occur in the intertrochanteric region, the prevalence of which increases exponentially with age. It is also associated with a high rate of morbidity and mortality. Beyond preventing avoidable deaths, the goal of the treatment is to restore patients to their pre-injury level of mobility. (5) Achieving stable reduction and fixation of the fracture, permitting immediate mobilization, is key to these goals.
Methods:
This is a descriptive cross-sectional hospital-based design study to evaluate the early Functional outcome of proximal femoral nail anti-rotation in the treatment of unstable intertrochanteric fractures conducted in 3 centers, and the total number in our study was 40 cases. Data were collected through a questionnaire that included patient data and analyzed using SPSS software (IBM Version-26).
Results:
Out of the Forty patients with an unstable intertrochanteric femur fracture (fractures A2.2 through A3.3), operated with PFNA enrolled in this study, 22 were males and the remaining were females. 24 patients had right hip fractures while 16 had left hip fractures. . Modified Harris Hip Score was used to assess postoperative pain, function, and functional activities.
There is a statistically significant difference between the mHHS and the age group, the functional outcome was excellent in young patient and the more patient’s age the less functional outcome and gender, and most of our patients score were fair and good. 17 female patients are fallen in this category while 12 male patients. All excellent patients are male group.
Conclusion:
Unstable intertrochanteric fracture is common in the elderly due to osteoporosis and in the young due to high-velocity trauma. As the fracture is more common in the elderly (80% of our study group), early reduction and internal fixation increases patient comfort, facilitates nursing care, and helps in the early mobilization of the patient. We believed our study had shown that the PFNA works well in the treatment of unstable intertrochanteric fractures, post-operative pain was ignored in most of our patients, 60% had slight limping not compromised their daily activity, most of them used a cane for walking 2-3 blocks, 52.5% climbed the stairs with banister, 72.5% put on socks/shoes with ease, 95.0% sitting in any chair for a long time and 62.5% entered public transportation. The overall functional outcome of our patients falls between good and fair.
UPLC-Q-TOF/MS-based metabolomics explored the metabolic mechanisms of thyroid cancer in different background
Authors: Sun Danyang , Zhang Yujie , Wang Dan , Zhao Xue , Han Rui , Li Ning , Li Xue , Li Tingwei , Wang Peng , Jia Qiang , Tan Jian , Zheng Wei , Song Lili , Meng Zhaowei
Published: January 2023

Thyroid papillary carcinoma (PTC) is the most common endocrine tumor, Hashimoto's thyroiditis (HT) is considered to be closely related to PTC pathogenesis, but their relationship still needs verification and exploration. Aim of the study. To analyze the differences and similarities of the metabolic mechanism of thyroid papillary carcinoma in normal and HT background, and to explore the relationship between HT and PTC. The Ultra performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UPLC-Q-TOF/MS) technology was used to analyze 61 PTC patient tissues (31 HT background and 30 normal tissue (NC) background). Potential biomarkers were screened from principal component analysis (PCA) to orthogonal partial least square (OPLS) discriminant analysis and further evaluated by ROC analysis. The HMDB was searched to identify potential differential metabolites and the final metabolic pathway analysis was performed by MetaboAnalyst 5.0. The HT and NC group had common metabolic pathways, such as taurine and hypo-taurine metabolism, arginine biosynthesis, alanine, aspartate and glutamate metabolism, arginine and proline metabolism and D-glutamine and D-glutamate metabolism. Furthermore, arginine, glutamic acid, cysteine, citric acid, malic acid, uracil and taurine showed statistical significance in PTC diagnosis (the area under the curve values of HT group and NC group were 0.867 and 0.973 respectively). The HT group had specific metabolic pathways, including aminoacyl-tRNA biosynthesis, glycine, serine and threonine metabolism. The metabolic profiles of the NC and HT groups had important similarities and differences in thyroid cancer. The correlation of PTC with HT may be related to aminoacyl-tRNA biosynthesis, serine and threonine metabolism.
Fixed Point Theorem for W-h Contraction Mappings In Generalized Menger Spaces
Authors: MBARKI ABDERRAHIM
Published: January 2023

In this paper, we study the problem of the existence of fixed points for weak-Hicks contractions in generalized Menger spaces. We will provide some examples to demonstrate the applicability and effectiveness of the theories and methods presented in the paper.
2010 Mathematics Subject Classification. Primary 54E70, 54H25. Secondary 47S50, 34B15.
Gastric Tumor Suppressor Genes Alterations Associated with cagA Positive H pylori among Patients with Gastric Cancer Systemic Review and Meta-Analysis
Authors: Hassan Abuobaida Alwasila , Abaker Mubarak Elnour , Osman Nazar Abdalazeem
Published: January 2023

Introduction: Gastric cancer is the fifth most frequent cancer worldwide After lung, breast, colorectal, and prostate cancers. Helicobacter pylori (H. pylori) is considered the most important causative agent of gastrointestinal diseases such as peptic ulcer, gastritis, gastric adenocarcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma.
Objective: to identify the tumor suppressor genes alterations associated with CagA in patients with gastric cancer.
Methods: All the available papers published before 2022 were collected by searching in PubMed and Scopus. The keywords included in the research were “H.pylori”, “gastric cancer”, “virulence factors”, “tumor suppressor genes” “ gene mutations” “cagA+” used by Boolean operators to obtain the articles with the keywords in their titles or abstracts.
Result: Initial searches yielded 111 articles, four articles were excluded as a duplication using the computer program Zotero (v5), then one hundred and seven articles were screened for the title and abstract evaluation using the Rayyan website, among them seventy-one articles were excluded. Thirty-six articles were scanned for full-text review and eligibility, furthermore, twenty-five articles were excluded because there were either Reviews and case reports, Not relevant studies, Insufficient data, and Unclear methods and results. Eleven articles were included for the literature review. In addition, the studies were in different regions of the world including Asia, Europe, North America, and Latin America. However, most of the studies were related to the USA.
Conclusion: Cag A can cause alterations on gastric tumor suppressor genes by either Decreased expression by increasing the methylation, inducing point mutation as mentioned, inactivation by increasing the methylation levels, increasing the levels of degradation and methylation the promotor of the tumor suppressor gene as mentioned
Changes in pollinator functional composition and plant –pollinator interaction networks in response to mangrove patch size and surrounding land use
Authors: Montoya-Pfeiffer Paula María , Monroy Carlos Eduardo Sarmiento , Montoya Augusto , Buenaventura Eliana , Rodríguez-Rodríguez Jenny Alexandra
Published: January 2023

Pollinators are declining worldwide as a result of land anthropization. However, several species have shown to be not affected or even benefited, since their responses depend on their functional traits that modulate their adaptability to particular environmental conditions. Pollinator responses may have important consequences on the structure of interaction networks, as the interacting species are sensitive to their counterparts. Despite the great importance that mangrove ecosystems have for human welfare, little is known about what is happening with pollinators' diversity and their interactions with mangrove species. This study investigates landscape effects on pollinator functional composition and their interactions with four dominant mangrove species in the Caribbean coast of Colombia. Pollinators of mangrove species Avicennia germinans, Conocarpus erectus, Laguncularia racemosa, and Rhizophora mangle were classified according to different functional traits and plant-pollinator interaction networks were created, with the aim to explore general patterns and to evaluate the effects of mangrove patch size and the surrounding land uses on pollinator functional composition and plant-pollinator interactions. Pollinator communities were mainly represented by wasps, flies, and bees, with the predominance of small and medium-sized predators, saprophagous, florivorous, no-social, and no-nesting species. Plant-pollinator interactions demonstrated a trend to niche differentiation in C. erectus and R. mangle, high number of interactions and pollinator species, as well as high values of interaction diversity and interaction evenness. Mangrove patch size decreased the richness of ground nesting wasps whereas increased network specialization, and urban size decreased the richness of predators, large-sized species, and ground-nesting wasps.
Intrinsic Friction Behaviour Originating from Molecular Structure of Lubricant in Nanoscale Gap Fabricated by Microelectromechanical Systems
Authors: Yagi Wataru , Xia Yuanlin , Tsuchiya Toshiyuki , Hirayama Tomoko
Published: January 2023

The purpose of this study was to obtain the friction properties reflecting the molecular structure of lubricant with a film-like specimen fabricated by MEMS technology. A bias voltage is applied to a film-like specimen to create a load between two surfaces by electrostatic force. This causes the specimen to deform. The two surfaces should then become parallel. A friction test was carried out by sandwiching n-hexadecane or toluene between the specimens. The friction property with n-hexadecane was a typical slip behaviour: transition from static to kinetic friction at a sliding velocity of 0.05–0.80 µm/s. The friction property with toluene was a characteristic slip behaviour depending on the sliding velocity: at 0.05–0.20 µm/s, a clear stick-slip motion was observed.
Developing and validating a Cashless Transaction Adoption Model (CTAM)
Authors: L Vimal Raj , S Amilan , K Aparna
Published: January 2023

This research intends to develop and validate a research model for the adoption of cashless transactions. For this purpose, this study was carried out using a two-stage approach. The first step in developing the conceptual framework for this study was undertaking an extensive evaluation of the prior research. Second, an empirical validation of the conceptual framework that was constructed in this research to investigate the use of cashless transactions was obtained. The study results reveal that twelve independent variables explained 84.7 percent of the variation in behavioural intention to adopt cashless transactions. In addition, performance expectancy is the strongest predictor of users' intentions to embrace cashless transactions, followed by perceptions of the economy's security and economic offence reduction, social influence, perceived trustworthiness, expected level of effort, and innovativeness. Further, in terms of impediments, perceived risk and cost are the negative influence factors influencing behavioral intention to adopt cashless transactions. Furthermore, this study's findings indicate that perceived economy's security (β = 0.279) was the second, and perceived economic offence reduction (β = 0.224) was the third most influential factor in adopting cashless transactions. These findings come from an evaluation of three new independent variables. Therefore, the CTAM has contributed to the literature by comprehensively explaining the user acceptability of cashless transactions. Consequently, this CTAM offers a more in-depth explanation than any other research for why individuals embrace cashless transaction systems.
Flow Management of First-Time Orders: A Dental Office Case Study
Authors: Majewski A. , Merkisz-Guranowska A. , Czarnota K.
Published: January 2023

The article presents the importance of managing the flow of first-time patients in a dental practice. Three main areas of difference between the popular linear model of dental office operation on the market and the author’s model of an integrated multi-specialist dental team were analyzed. Performance indicators for working with first-time patients illustrating the ability to manage the flow of patients in the office, communicate with patients, build patient awareness of oral health conditions, and harness patients’ potential for treatment are presented and discussed. It was proven that with the fuller utilization of patients’ potential for treatment, a noticeable effect is a simultaneous increase in the profitability of the dental practice, which, with an entirely ethical process based solely on diagnosed dental problems, makes both profitable.
Kurumsal Karbon Ayak İzi Analizi: Bir Kimya Fabrikası için Örnek Hesaplama
Authors: ÇOLAK Gözde , ATILGAN TÜRKMEN Burçin
Published: January 2023

Sürdürülebilir kalkınma kavramı, insanlığın gelecek nesillere yaşanabilir bir dünya bırakamaması riskiyle birlikte son yıllarda ortaya çıkmıştır. Sürdürülebilir kalkınma süreci ekonomik büyüme, çevrenin korunması ve sosyal sorumluluk alanlarındaki gelişimlere paralel olarak ilerleyebilmektedir. İklim değişikliği, sürdürülebilir kalkınma için büyük bir tehdittir ve sanayileşme, kentleşme ve enerji tüketimi gibi faktörlerin bir sonucu olarak etkileri daha görünür hale gelmektedir. İklim değişikliğinin etkilerini hafifletmek için sera gazı emisyonlarının hızla azaltılması gerekmektedir. Sera gazı emisyonlarının azaltılmasında en önemli adım, emisyonların kaynağının, nasıl üretildiğinin ve gerekli iyileştirme önlemlerinin belirlenmesidir. Bu amaçla bireysel, kurumsal veya sektörel karbon ayak izi hesaplaması yapılmaktadır. Bir şirketin kurumsal karbon ayak izinin hesaplanması, çoğu zaman iklim değişikliğiyle mücadelenin başlangıç noktasıdır. Bu hesaplama ile işletmenin faaliyetleri içerisinde en fazla sera gazına sebep olan noktalar bulunarak iklim değişikliğine olan etkiyi azaltabilmek için gereken hedefler belirlenmektedir. Bu hesaplama, işletmenin faaliyetlerinde en fazla sera gazının kaynaklarını tanımlar ve iklim değişikliğinin etkisini azaltmak için gereken hedefleri belirler. Bu çalışma sera gazı emisyonları, kurumsal sürdürülebilirlik, kurumsal karbon ayak izi ve hesaplama yöntemlerine genel bir bakışın yanı sıra kurumsal düzeyde karbon ayak izi hesaplayıcıları tarafından rehber olarak kullanılabilecek örnek bir hesaplama içermektedir.
The Use of English Songs to Teach Listening Skill
Authors: Ulfa Maria
Published: January 2023

There are four English skills that determine the learner’s performance in English. One of the very important skills is listening. The successful learning not only depends on the learner but also to the teacher. Teaching listening is one of the important thing that English teacher must know how to teach it. Teaching listening is not easier because not all of learners like listening. The teacher must create the enjoyable atmosphere, fun and interesting situation as possible as teacher can. The enjoyable atmosphere will have good effects on the education, because if they dislike the subject it will drop their spirit as soon as possible. In other word, the teacher should make learning enjoyable because many students like listening song and learn well when they are enjoying themselves. Using song can be boastful to motivate the students in learning English as well to enhance their ability in listening skill.
On the generality of symmetry breaking and dissipative freezing in quantum trajectories
Authors: Tindall Joseph , Jaksch Dieter , Sánchez Muñoz Carlos
Published: January 2023

Recently, several studies involving open quantum systems which
possess a strong symmetry have observed that every individual trajectory
in the Monte Carlo unravelling of the master equation will dynamically
select a specific symmetry sector to ‘freeze’ into in the long-time
limit. This phenomenon has been termed ‘dissipative freezing’, and in
this paper we argue, by presenting several simple mathematical
perspectives on the problem, that it is a general consequence of the
presence of a strong symmetry in an open system with only a few
exceptions. Using a number of example systems we illustrate these
arguments, uncovering an explicit relationship between the spectral
properties of the Liouvillian in off-diagonal symmetry sectors and the
time it takes for freezing to occur. In the limiting case that
eigenmodes with purely imaginary eigenvalues are manifest in these
sectors, freezing fails to occur. Such modes indicate the preservation
of information and coherences between symmetry sectors of the system and
can lead to phenomena such as non-stationarity and synchronisation. The
absence of freezing at the level of a single quantum trajectory provides
a simple, computationally efficient way of identifying these traceless
modes.
Language Learning Anxiety : a bometric investigation of stress and language learning using wearable devices
Authors:   , MacDonald William Tait
Published: January 2023

As Sapolsky (2015) notes, stress research has long been characterised by definitional debates that gave rise to a lack of agreement between theorists. An example of this definitional confusion can be seen in the area of Language Learning Anxiety, where there appears to be confusion in the literature over terms such as anxiety and stress. This study investigated the link between stress and language learning using wearable devices measuring heart rate variance, as a means of establishing the feasibility of using this new technology in stress research. The results indicate that the contextualised longitudinal data delivered by wearable devices mitigates against the current dominant paradigm in Language Learning Anxiety, which postulates a straight-line negative correlation between stress and learning. Instead, the inverted U stress relationship proposed by theorists such as Hebb (1955) seem to be a better fit for the data. The nature of the contextualised data generated in this study allowed for comparisons between participants’ stress readings in academic contexts, such as language and non-language classes, and their free time. The findings suggest that certain long-held assumptions about heightened stress in academic contexts may not hold true. While the findings of this study did not reach the levels of statistical significance, they constitute proof of concept that the type of contextualised data delivered by wearable devices may allow for a new type of stress research that incorporates contextualising longitudinal perspectives on participants’ stress levels. In this study the inclusion of contextualising data led to fundamentally different conclusions about the relationship between stress and language learning. The same may be true of many areas of stress research. The findings presented in this study have broader paradigm-altering implications not only for educational policy, but also for stress research in general. Perhaps equally important was that the type of data delivered by wearable devices was qualitatively different from that normally associated with quantitative studies. This presented challenges in data analysis in this study, but also opens intriguing possibilities regarding a means of reconciling the qualitative and quantitative split in research modalities. The use of wearable devices is not without issues, and some of the issues, ranging from practical considerations to ethical conundrums, are presented for the reader’s consideration and to inform future researchers regarding potential pitfalls.
Analysis of Ruangguru as the Online Learning Media on Chemistry Learning
Authors: Mas'udah Mas'udah , Agung Salamah , Bahriah Evi Sapinatul
Published: January 2023

Ruangguru is one of the leading online education platforms in Indonesia that has followed a learning system based on the applicable curriculum. There is a need for analysis to find out how capable the Ruangguru application is in supporting online learning activities. Therefore, this study aimed to know the process of learning chemistry in the Ruangguru online learning media, especially on the solubility product and solubility product constant (Ksp). The type of research used was descriptive qualitative. Data collection techniques used observation and documentation. The results showed that the Ruangguru application met the criteria in supporting the online learning system of solubility and solubility product constant (Ksp) materials, which had facilities with learning materials delivered via live streaming video with the guidance of online tutors. In addition, there were facilities that could support all student activities, such as the availability of study modules, study groups, and learning evaluations. These are in order to improve students understanding abilities and have a good impact on the learning outcomes obtained, which has facilities with learning materials delivered via live streaming videos with the guidance of online tutors.
Design of Chemo-entrepreneurship Oriented Teaching Materials to Analyze Students' Entrepreneurial Creativity
Authors: Wildana Maula Najikh , Sumarti Sri Susilogati , Susilaningsih Endang , Nuryanto Nuryanto
Published: January 2023

Studying Chemistry is not about the concept but how to train the students' creativity. The learning outcomes are influenced by several factors, including learning models and materials. Teachers still use the books provided by the school, so teachers should develop learning materials that suit learning objectives and students' conditions. Teachers should analyze the students' cognitive ability and also creativity. Chemo-entrepreneurship-oriented learning materials would help to analyze students' cognitive ability and entrepreneurial creativity. This research used research and development with ADDIE method. Results were the validity of material instrument from three experts gave very valid with the scores of 49, 50, and 48. The learning materials got a very good category from teachers' responses with a score of 34 out of 40 and got a good category from students' responses with a score of 38.53 out of 48. Results from the analysis of students' entrepreneurial creativity showed that students had high entrepreneurial creativity. Students also actively discussed and made creative products. There were aromatherapy candles, banana nuggets, apple donuts, and crispy balado potatoes.
The Implementation of STEM-Based Lipid E-Book on Student Learning Outcomes
Authors: Handayani Dewi , Alperi Muzanip , Uliyandari Mellyta
Published: January 2023

The purpose of the study  was to analyze the effect of using lipid e-books using the STEM approach on student learning outcomes. The method uses pre-experimental research with one group pretest posttest design. This research was conducted at one of the State Universities in Bengkulu with the subject consisting of 26 students who took the Organic Chemistry 2 course. The instrument used in this study was a multiple choice test with 4 meetings in the form of pretest and posttest questions. Data analysis techniques include the average value (mean), normality test, and hypothesis testing using a t-test using the SPPS for windows version 23 computer program. The results showed the average score of the learning outcomes before using the lipid organic chemistry e-book was 54.90, while after using the e-book the average value is 79.81. The learning outcomes data were normally distributed and the t-test value showed Significant (2-tailed) 0.00. These results indicate that the developed STEM-based teaching materials can improve student learning outcomes in particular and are able to improve the quality of learning for organic chemistry 2 courses in general.
Phenomenology of Conceptual Understanding Ability, Representation, and Student Algorithm on Stoichiometry Materials
Authors: Fitriani Aulia Rizki , Rahmawati Atik , Lathifa Ulya
Published: January 2023

One of the basics in studying quantitative chemistry is stoichiometry. Thus, skills are needed that can support students in studying stoichiometry. The purpose of this study was to determine the level of students' conceptual understanding, representation, and algorithm skills in stoichiometric material. The subjects in this study were students of the 2019 class D Chemistry study program who had studied stoichiometry in the Basic Chemistry course I. This study was a descriptive study, had a qualitative approach, and used a phenomenological design with research techniques such as tests and interviews. The results showed that the level of students' conceptual understanding ability was 32.5% in the intuitive understanding category, 37.5% in the functional misconception category, 6.25%, in the partial understanding category, 1.25% in the correct incomplete understanding category, and 22. ,5% best understanding category. The level of student representation ability in submicroscopic phenomena was 13.53% and symbolic phenomena was 70.13%. Meanwhile, the level of students' algorithmic ability is in the unstructural category, 3.75% in the multistructural category, 43.75% in the relational category, and 0% in the extend abstract category.
Development of Learning Model Tools STEAM-based SCT in Wetland Environment Theme
Authors: Norsalehah Norsalehah , Leny Leny , Rusmansyah Rusmansyah , Sholeha R A
Published: January 2023

This study aimed to produce learning tools that meet the eligibility criteria based on the level of validity, practicality, and effectiveness. This study used methods of RD with a 4D development model. The study was conducted with 5 students on individual trials, 9 students on small group trials, and 35 students on limited trials. The results showed: (1) Validity, expert validation results for lesson plans, and students' worksheets were obtained at 99.3% and 87.3% (accurate); (2) Practicality, from the results of students' responses to questionnaires on individual trials of 3.44 (good), small group trials of 4.29 (good), student response questionnaires of 3.93 (good), teacher's response questionnaires on learning and lesson plans of 4.70 and 4.30 (very good) and observations of the implementation of learning using lesson plans of 4.29 (excellent); (3) The effectiveness was seen in the average N-gain score for creative thinking abilities and self-efficacy of students, namely 0.54 (medium) and 0.73 (high). Overall the development of this learning device had met the eligibility criteria to train students' creative thinking skills and self-efficacy.
Waste to resource: Utilization of waste bagasse as an alternative adsorbent to remove heavy metals from wastewaters in sub-Saharan Africa: A review
Authors: Lemessa Gemechu , Gabbiye Nigus , Alemayehu Esayas
Published: January 2023

Heavy metals pollution of both surface and groundwater sources of sub-Saharan Africa is alarmingly increased due to unplanned urban populations. Inadequate policies for water management, political commitment, and financial resources forced 65% of rural communities of sub-Saharan Africa to live in economic water stress areas. Sugarcane bagasse (SCB) shows high heavy metals (HMs) adsorption capacity (20–700 mg/g) through chemical entrapments to carbon-oxygen containing functional group and interior pore filling of porous surface. Various modifications like a physical/thermal, chemical, and composite form of bagasse show better adsorption performance for HMs removal. Kinetic and isotherm studies of HMs adsorption equilibrium data over SCB show that both Langmuir and Freundlich adsorption isotherms (cooperative adsorption) as the main adsorption mechanism. In addition, SCB shows potential bio-adsorbent properties for the selective adsorption of target HMs based on their physicochemical properties and shows good repeatability in acid environments. It is believed that information on this review will shed light on the current and future prospects of raw and modified SCB for HMs adsorption removal capacity. Sugarcane bagasse shows a remarkable selectivity for HMs adsorption removals based on their physicochemical properties and shows good potential capability for future utilizations in real wastewaters of developing countries.
Urban water insecurity drivers in the Brazilian semi-arid region
Authors: Ramos Filho Rivaildo da Silva , Filho Mauro Normando Macêdo Barros , Alves Rufino Iana Alexandra , França da Costa Fagner , de Sousa Cordão Maria José
Published: January 2023

The imbalance between water supply and demand highlights the vulnerability of many people and the prospect of an uncertain future for water supply. This work aims to compare the Urban Water Security Index (UWSI) with three other methodologies (percentage flow duration curve, Urban Water Sustainability Indicator, and accumulated data from the Drought Monitor) for the municipality of Guarabira, Paraíba, Brazil. The results show water security based on the amount of water in the study area. However, there is a need for proposals for assessing urban water security to be based on local sustainability. Water-sensitive planning is the solution to maintaining and conserving natural resources for future generations in the face of impacts, particularly climate change and population growth. The methodology applied in this work can contribute to the investigation of probable and specific causes of water insecurity and gives evidence of improvement in the concept of water security based on the urban metabolism of water.
gestão do conhecimento no sistema de ensino STEM/STEAM
Authors: Teixeira Flávia Dantas de Azevedo , Boertolozzi Flávio , Almeida Iara Carnevale de , Zagonel Yasminn Talyta Tavares
Published: January 2023

A educação STEAM (“Science, Technology, Engineering, Art and Mathematics”, em português “Ciências, Tecnologia, Engenharia, Arte e Matemática”) pretende cultivar cidadãos alfabetizados no modelo através da capacitação dos alunos com conhecimentos, habilidades e valores para o século 21. A Gestão do Conhecimento (GC) oferece recursos para viabilizar essas conexões entre disciplinas e docentes. Este estudo tem como objetivo geral analisar a possibilidade dos ambientes Ba (físico e virtual) serem mediados pela GC. A pesquisa é de natureza aplicada, com abordagem qualitativa, através de modelo hipotético-dedutivo com coleta de dados via revisão da literatura. Como resultado, apresenta-se uma análise sobre as possibilidades dos ambientes físico e virtual serem mediados pela GC, onde constatou-se a importância de se estabelecer um ambiente propício para criação e compartilhamento do conhecimento. Além disso, deve-se aplicar métodos eficientes e sistemáticos para gerenciar o conhecimento dentro da organização de ensino.
Guia instrucional para professores de física
Authors: Mendes Jéssica dos Reis , Cordeiro Júnior Dirceu Antônio
Published: January 2023

Docentes capazes de reconhecer os benefícios que as tecnologias podem trazer ao processo de ensino-aprendizagem conseguem atuar de maneira mais atraente e inovadora junto aos seus alunos, tanto em sala de aula quanto no estímulo aos estudos complementares. Nesse contexto, o presente trabalho apresenta uma proposta de desenvolvimento e análise de um produto educacional para professores de Física, com o objetivo de estimular os estudos extraclasse por meio da utilização da plataforma Padlet. Trata-se de uma pesquisa de abordagem qualitativa realizada com a participação de duas turmas do terceiro ano do Ensino Médio. Após a análise dos resultados, é possível sugerir que a utilização da plataforma digital, em associação com estratégias pedagógicas adequadas, pode auxiliar em um ensino mais dinâmico, promovendo a relação entre os conteúdos básicos curriculares, a realidade e as expectativas dos alunos, incentivando a construção do conhecimento de forma mais abrangente e eficaz.
Nietzsche educador e a afirmação da singularidade
Authors: Hardt Lúcia Schneider
Published: January 2023

O artigo tem por objetivo explicitar o impacto de Schopenhauer sobre Nietzsche como um estilo de mestre, incorporando a singularidade como aquilo que a educação promove. Para contemplar esta tarefa e atualizar a reflexão para o nosso tempo, faz-se necessário enfrentar a tensão entre as demandas das instituições educacionais e a potência de um mestre na prática do seu ofício, a fim de buscar em cada estudante aquilo que ele tem de genuíno e original. Trata-se de um ensaio de abordagem qualitativa que reflete a trajetória formativa do próprio Nietzsche, capaz de promover sua condição extemporânea e enfrentar a cultura de sua época. Educar, formar-se, é uma tarefa que exige paciência, persistência, rigor, disciplina. Para isso, um mestre é necessário, de preferência, como nos indica Nietzsche, portador de uma serenidade admirável, cheio de um fogo forte e devorador para ser capaz de promover a singularidade do seu aluno.
brincar na educação infantil e suas relações com a formação e visão dos professores
Authors: Colete Fernanda Cândido Figueiredo Monteiro , Mariotti Milton Carlos
Published: January 2023

O brincar é uma das principais abordagens no processo de ensino na primeira infância, sendo defendido por diversos autores com autoridade no tema, como Vygotsky, Piaget, Kishimoto, Montessori, e descrito pela Base Nacional Comum Curricular como um dos direitos de aprendizagem e desenvolvimento da criança. Esse estudo teve como objetivo identificar a visão do brincar como prática utilizada por educadores do ensino infantil de diversos países. A metodologia abordada foi a Revisão de Escopo, com busca em cinco bases de dados, totalizando 19 artigos selecionados. As contribuições dos artigos foram relevantes para demonstrar que o brincar, como prática na educação infantil, não está completamente difundida, ainda não tem a valoração correspondente aos seus benefícios no processo de aprendizagem da criança e na formação dos professores, e a aplicação de práticas pedagógicas ainda não têm o olhar para o brincar como foco essencial para os currículos pré-escolares.
internacionalização em casa na pós-graduação na América Latina e Caribe na modalidade a distância
Authors: Pereira Vilmar Alves
Published: January 2023

Este estudo tem por objetivo apresentar reflexões a partir da experiência de estudantes em nível de doutorado sobre a modalidade da Internacionalização em Casa no contexto da Pós-graduação, através da Educação a Distância. Pesquisa de horizonte qualitativo com abordagem da Hermenêutica Filosófica, num primeiro momento, apresenta demarcações conceituais sobre a necessidade da internacionalização, suas formas e desafios no contexto da região da América Latina e Caribe. Num segundo, apresenta resultados de uma experiência com estudantes que vivenciam esta modalidade no Chile, Colômbia e Brasil. Os resultados expressam as motivações, avaliações, aprendizagens e desafios em cursar um doutorado nessa modalidade. A internacionalização em casa na Pós-graduação propicia a emergência de uma nova relação entre uma instituição internacional diretamente com o estudante. Para os estudantes, a satisfação está na realização de um curso que em outros moldes não seria possível sem perder os vínculos pessoais e profissionais. O maior desafio passa pela disciplina e gestão de espaços e tempos de estudo.