bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Foreign Direct Investment to the Quality of the Environment in Indonesia
Authors: Hadi Sasana , Retno Sugiharti , Yuliani Setyaningsih
Published: December 2018

Foreign Direct Investment (FDI) is the main element of the industrial development and economic growth. FDI will bring spillover effect in the form of technology transfer, increased competitiveness and surely will open up employment. But the presence of FDI into the country is not necessarily without problems. In the massif, the presence of FDI will build new factories that will bring the potential negative environmental externalities. This research aims to analyze the impact of FDI on the quality environment represented by CO2 emissions. In addition to the FDI also hosted other macroeconomic variables to see the impact on the environment in the aggregate economy. By using the time series regression analysis, the results show that the presence of the FDI has positive effects significantly to an increase in CO2 emissions. While the other macroeconomic variable, namely, poverty and population growth has a negative effect against CO2 emissions.
Monitoring System Heartbeat and Body Temperature Using Raspberry Pi
Authors: Sollu Tan Suryani , Alamsyah  , Bachtiar Muhammad , Bontong Benyamin
Published: December 2018

The development of the current monitoring system has become interesting to investigate, especially wireless sensor network based monitoring. Implementation of the wireless-based monitoring system widely implemented in the application of natural disasters, health monitoring, and military operations. One of the health services applications is the monitoring system of heartbeat and body temperature. Examination of the vital sign is a fundamental parameter for medical personnel in performing treatment early to maintain the safety and physical condition of patients. However, the problems that occur in health services is that medical staff need a long time to examine patients, patient data retrieval is still conventional, and equipment used still using the cable media. To solve the problem, the authors propose a heart rate monitoring system and body temperature using Raspberry Pi. This study aims to relieve the burden of medical personnel in monitoring the patient, shorten the time in taking patient data, and reduce the occurrence of misdiagnosis. Test results showed that the success rate of the system in detecting the heartbeat of 97.78% and body temperature of 99.73%. Distance range of sensor data transmission for open space without obstructions of 67 meters and enclosed space with a barrier of 13 meters.
Implementation Data Mining using Decision Tree Method-Algorithm C4.5 for Postpartum Depression Diagnosis
Authors: Supriyanto Aris , Suryono Suryono , Susesno Jatmiko Endro
Published: December 2018

Postpartum depression is a serious problem that needs to be addressed because it has negative effects on family, child welfare, cognitive, and mother child interactions. Diagnosis is done based on psychological condition, blood pressure, respiration, body temperature, and classification data extract by decision tree C4.5 algorithm method. Results of this study in the form of an online information system that can identify the level of depression more quickly and precisely. The results showed the greatest gain on the psychological variables of 0.57 node 1, blood pressure 0.54 node 2, body temperature 0,54 node 3, means that the three variables are more influential on the condition of depressed patients, and should be given priority treatment. Test results from 50 patients with 50 examinations showed 62% prevalence, 65.62% sensitivity, specificity 77.77%, negative predictive value of 56%, and positive predictive value 84%, and
Information System of Performance Assesment on Startup Business using Simple Multi-Attribute Rating Technique Exploiting Ranks (SMARTER)
Authors: Tangkesalu Alen Adriyanti , Suseno Jatmiko Endro
Published: December 2018

Performance evaluation system has a very strategic role in improving the performance of a company. Companies generally judge performance based only on the financial aspect only, regardless of other aspects that are also not less important. This study aims to build a performance evaluation system using a Balanced Scorecard perspective framework that is a financial perspective, customer perspective, internal business process perspective and learning and growth perspective, which can assist decision makers in evaluating performance and prioritizing competitive alternative measures in enhancing the achievement of strategic objectives company. Implementation of the Simple Multi-Attribute Rating Technique Exploiting Ranks (SMARTER) method of performance evaluation system provides the right performance evaluation data. The data were obtained by calculating the criteria and sub-criteria weightings from 4 perspectives and 14 key performance indicators (KPIs) based on the BSC perspective using Rank Order Centroid (ROC) weighting to obtain criteria and sub-criteria rating according to importance level. Base on case studies, the results of this research indicate that the perspective of internal business processes with a priority weight of 0.521 is the most important perspective in evaluating business startup performance, then the customer perspective with a weight of 0.271, then learning and growth perspective with a weight of 0.146 and perspective finance with a weight of 0.063. While the asset turnover performance indicator with a weight value of 0.009 and profit investment with a weight of 0.004 from a financial perspective are important factors for improvement.
Implementation of Advanced Encryption Standard (AES) and QR Code Algorithm on Digital Legalization System
Authors: Okfalisa  , Yanti Novi , Surya Wahyu Aidil Dita , Akhyar Amany , Frica A Ambarwati
Published: December 2018

A certificate is an important document that its validity must be ascertained. Fraud over the originality of this document demands a high level of security to ensure that this document is genuine. The Digital Certificate Legalization system (DCL) can regulate and guarantee the mechanism of document validity procedure. By implementing AES and QR Code algorithm, the information contained in the photo-scan of the certificate can be authenticated. The results of the scan are encrypted by using the legalized code in AES Algorithm. The code will be translated using the QR Code and matched to the data contained in the server system. The system will confirm whether the certificate is original or not. In order to test the system, black box testing is applied for functionality check; capacity testing in terms of execution time and memory load of benchmark testing are also examined for system performance measurement. Finally, user response testing is conducted to identify the user acceptance towards the system. As the result, the implementation of AES and QR Code algorithm provides good performance, efficient, light, and fast execution responses (less than one second and less than one megabyte) in a legalized certification checking system.
Integration of Internet Technology to Support The Wayang Orang Ngesti Pandawa Business
Authors: Widiantoro Albertus Dwiyoga , Sanjaya Ridwan , Raharjo Tjahyono , Winarno A. Rachmat Djati
Published: December 2018

Wayang orang is one of the cultural heritages that until now is still being preserved. However, the wayang orang Ngesti Pandawa in Semarang ifaces difficulty in attracting an audience. The number of viewers are few and limited to residents of Semarang and its surroundings. Internet technology, financial technology, website, social media integration, and government support is expected to increase the interest of people to attend the performances. This study examines the view of new students towards the Ngesti Pandawa wayang theatre. The results shows that young people are still interested in the wayang orang Ngesti Pandawa. They also have given various inputs on how to increase the audience number and keep the Wayang Orang well preserved
Analysis of Electrical Properties Using the four point Probe Method
Authors: Waremra Richard S. , Betaubun Philipus
Published: December 2018

There has been conducted Physics research on a material, that is, monitoring electric characteristic of a material using four-point probe method. This research measures current and voltage. The result is used to determine resistivity of a material. The research uses 2 samples, that is, chalk and charcoal. The result shows the resistivity of the sample in the form of bulk (t>s) for chalk has high resistivity on voltage of 6.6 Volt. Meanwhile, resistivity on thick sheet (ts) is in 6 Volt, and on large resistivity (t<s) is in 6.6 Volt.
The specific cultural terms and expressions in the translation of literary work (novel)
Authors: Purnomo Mulyo Hadi , Baharuddin Baharuddin
Published: December 2018

Specific terms in relation to geographic names and expressions of different culture often make difficulties for translators of literary works especially novel. This article is an investigation-based work on the translation work of an English-published novel into Bahasa Indonesia. The research studied the terms and expressions available in the translation version used by the translators in translating the novel into Bahasa Indonesia version. Some theories were applied in the data analysis such as the related factors that, during the translation, help the translator finish his work which sometimes is identified as a very difficult work, especially during making decision which translation theory to refer to and to apply as well as to select which principle to convey. This is crucial due to whether the translators should urge the receptor expression or to keep the original thought of the source terms. In some terms, translation should be faithful in one hand and beautiful in other hand, should be literal to keep the original and be free to smoothly pass the message to the readership. The research then showed that the translation is sometimes smooth but broken in other places. The research finally emphasized the truth of never-lasting dichotomy of translation between the attempt to maintain the form or the struggle for the content. This had long been discussed not only in years but also decade by decade even in centuries.
SLALOM: Open-source, portable, and easy-to-use solar cell optimizer. Application to the design of InGaN solar cells
Authors: Ould Saad Hamady Sidi , Fressengeas Nicolas
Published: December 2018

The design and optimization of novel structures is an essential part of the next-generation solar cells development. Indeed, the technological steps involved in the development of high-performance solar cells involve a huge set of interdependent physical and geometrical parameters: layers thicknesses, dopings, compositions, and defect characteristics. In this work, we propose a new open-source and free solar cell optimizer: SLALOM − for SoLAr ceLl multivariate OptiMizer − that implements a rigorous multivariate approach, which improves from the one-parameter-at-a-time procedure that is traditionally used in the field to a state-of-the-art multivariate approach. Applied to indium gallium nitride (InGaN) solar cells, it shows its potential to become a useful tool for the development of novel solar cells. SLALOM is implemented to be extended to any semiconductor simulation engine. Several models for solar cells have been implemented in SLALOM, including, for instance, InGaN. One can adapt these models to any solar cell technology by changing the parameter set, the here proposed generic code structure remaining unchanged.
Produktion und Qualitätskontrolle von Radiopharmaka mittels zugelassener Kits
Authors: Gildehaus Franz
Published: December 2018

Seit Jahrzehnten ist die Präparation von kommerziellen Markierungskits mit 99 mTc etablierte Praxis. Mit der 15. Novelle des Arzneimittelgesetzes (AMG) kam es zu einer rechtlichen Neubewertung der Eigenherstellung dieser Kit-Radiopharmaka. So wird diese Tätigkeit nunmehr eindeutig als pharmazeutische Herstellung im Sinne des AMG eingestuft, die bei den zuständigen Behörden angezeigt werden muss und auch der behördlichen Inspektion unterliegen (kann). Da eine umfassende Qualitätssicherung der 99 mTc-Kits gemäß den gültigen pharmazeutischen Standards den meisten Betreibern unmöglich ist, muss man sich aber dennoch den Qualitätsanforderungen, die an selbst hergestellte Arzneimittel gestellt werden, bewusst sein. Als radioaktive Arzneimittel bezeichnet man radioaktive Verbindungen, die sowohl für diagnostische Fragestellungen als auch für therapeutische Interventionen bei verschiedensten Erkrankungen eingesetzt werden können. Im Allgemeinen besitzen sie keine pharmakologischen Effekte, da sie nur in sehr geringen Mengen (mikro- bis nanomolarer Bereich) verwendet werden. Dosis-Wirkungs-Beziehungen treten im Gegensatz zu „normalen“ Pharmaka äußerst selten auf. Dennoch unterliegen sie als Parenteralia einer Reihe von biologischen Qualitätskriterien wie Sterilität und Pyrogenfreiheit, aber auch physikochemische Kriterien wie chemische, radiochemische Reinheit und Radionuklidreinheit müssen den Vorgaben entsprechen. Gerade die beiden letztgenannten sollten regelmäßig vom Anwender, der letztlich für die Bereitung der Markierungskits verantwortlich ist, überprüft werden. Dazu stehen eine Reihe schneller und einfacher Verfahren wie die Dünnschicht- oder Säulenchromatografie mittels Kartuschen zur Verfügung. Unter Verwendung dieser Methoden lässt sich ein einfaches und effizientes Qualitätssicherungssystem für das nuklearmedizinische Labor etablieren, das eine hohe Produktqualität garantieren kann.
Gut Hormone Responses to Mixed Meal Test in New-Onset Prediabetes/Diabetes After Acute Pancreatitis
Authors: Pendharkar Sayali , Singh Ruma , Cervantes Aya , DeSouza Steve , Bharmal Sakina , Petrov Maxim
Published: December 2018

The study was aimed to investigate gut hormone responses to mixed meal test in individuals with new-onset prediabetes or diabetes after acute pancreatitis (cases) compared with healthy controls, and the effect of body fat parameters. A total of 29 cases and 29 age- and sex-matched healthy controls were recruited. All participants were given standard mixed meal drink and blood samples were collected to measure dipeptidyl peptidase IV, gastric inhibitory peptide, glucagon like peptide-1, insulin, oxyntomodulin, and peptide YY. Body fat parameters were measured using magnetic resonance imaging. Repeated measures and linear regression analyses were conducted in unadjusted and adjusted models. Gastric inhibitory peptide levels were significantly higher whereas oxyntomodulin levels were significantly lower in cases compared with controls in both the unadjusted (p<0.001 and p<0.001, respectively) and adjusted (p<0.001 and p<0.001, respectively) models. In cases, liver fat % contributed up to 13.4% (vs. 2.9% in controls) to variance in circulating levels of gastric inhibitory peptide whereas body mass index - up to 20.8% (vs. 9.9% in controls) in circulating levels of oxyntomodulin. New-onset prediabetes/diabetes after acute pancreatitis is characterised by increased levels of gastric inhibitory peptide and decreased levels of oxyntomodulin. Further, liver fat % and body mass index appear to be the body fat parameters that contribute most significantly to gastric inhibitory peptide and oxyntomodulin levels, respectively.
Artifacts and Technical Restrictions in 2D Shear Wave Elastography
Authors: Bouchet Pierre , Gennisson Jean-Luc , Podda Andrea , Alilet Mona , Carrié Mathieu , Aubry Sébastien
Published: December 2018

2 D shear wave elastography (2D-SWE) is the latest evolution of elastography techniques and allows real-time quantitative assessment of the medium stiffness. The aim of this review is to identify, describe, explain and illustrate some technical restrictions and artifacts in 2D-SWE. Encountered artifacts and technical restrictions may be categorized according to acquisition technique, medium, or operator:

Clear knowledge of the underlying physical basis is necessary in 2D-SWE because radiologists have to deal with technical restrictions and a wide range of artifacts. Proper use of 2D-SWE ensures the reliability and reproducibility of the technique.
The Impella Device: Historical Background, Clinical Applications and Future Directions
Authors: Glazier James J. , Kaki Amir
Published: December 2018

The Impella device is a catheter-based miniaturized ventricular assist device. Using a retrograde femoral artery access, it is placed in the left ventricle across the aortic valve. The device pumps blood from left ventricle into ascending aorta and helps to maintain a systemic circulation at an upper rate between 2.5 and 5.0 L/min. This results in almost immediate and sustained unloading of the left ventricle, while increasing overall systemic cardiac output. The most common indications for using the Impella device are in the treatment of acute myocardial infarction complicated by cardiogenic shock and to facilitate high risk coronary angioplasty. Other indications include the treatment of cardiomyopathy with acute decompensation, postcardiotomy shock, and off-pump coronary bypass surgery. A growing body of observational and registry data suggest a potentially valuable role for the Impella system in reducing the mortality associated with cardiogenic shock. However, there are, as of yet, no randomized controlled trial data supporting this observation.
Diffuse Esophageal Leiomyomatosis in Pediatric Patients: A Systematic Review and Quality of Evidence Assessment
Authors: Ziogas Ioannis A. , Mylonas Konstantinos S. , Tsoulfas Georgios , Spartalis Eleftherios , Zavras Nikolaos , Nikiteas Nikolaos , Schizas Dimitrios
Published: December 2018

Background Diffuse esophageal leiomyomatosis (DEL) is a rare disorder characterized by benign hypertrophy of esophageal smooth muscle cells. No rigorous summary of available evidence on how to best manage these patients exists.

Objective To define the clinical features and outcomes of pediatric patients with DEL.

Materials and Methods A systematic literature search of the PubMed and Cochrane databases was performed with respect to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (end-of-search date: October 6, 2018). The algorithm: “esophageal leiomyomatosis AND (children OR pediatric*)” was implemented.

Results Thirty-five studies including a total of 58 patients were analyzed. The female:male ratio was 1.45:1. Mean patient age was 8.54 ± 4.67 years. The most common disease manifestations were dysphagia and gastrointestinal symptoms (90.0%, 95% confidence interval [CI]: 78.2–96.1), followed by failure to thrive (57.9%, 95% CI: 36.2–76.9) and pulmonary symptoms (56.4%, 95% CI: 41.0–70.7). Alport syndrome (AS) was seen in 57.7% (95% CI: 44.2–70.1) of the patients. The most commonly implemented procedure was esophagectomy (85.2%; n = 46/54; 95% CI: 73.1–92.6) with gastric transposition (37.8%; n = 17/45; 95% CI: 25.1–52.4). Postoperative complications developed in 33.3% (n = 15/45; 95% CI: 21.3–48) of the patients. All-cause mortality was 7.0% (95% CI: 2.3–17.2) and disease-specific mortality was 3.5% (95% CI: 0.3–12.6).

Conclusion DEL is an uncommon condition that typically occurs in the setting of AS. Esophagectomy with gastric transposition is the mainstay of treatment. Although complications develop in one-third of the patients, mortality rates are low.
The Comparison of Postoperative Outcomes Open and Closed Reduction for Patellar Fractures
Authors: Lee Si Young , Choi Jun Young , Lee Hyun Il , Lee Jung Min , Cho Jin Ho
Published: December 2018

Patellar fractures account for approximately 1% of all human body fractures. This study aimed to compare the surgical outcomes of open reduction and closed reduction for patellar fractures. This retrospective study included 62 patients (63 cases) who underwent surgical treatment of patellar fractures from 2008 to 2013. Of the 63 cases, open and closed reductions were performed in 42 and 21 cases, respectively. Plain radiography was used to assess fracture healing. Comminuted patellar fracture was the most common fracture type in both groups. Tension band wiring and cannulated screw fixation were mainly used in the open and closed reduction groups, respectively. There was no significant difference in the modified hospital for special surgery score, visual analog scale score for pain, and range of motion between the two groups. The mean union time was 3.2 and 3.0 months in open and closed reductions, respectively. Postoperative knee stiffness was noted in five cases of open reduction and in three cases of closed reduction. One patient in the open reduction group had a refracture. There were no notable differences in treatment outcomes between open and closed reductions. Thus, closed reduction may not be inferior to open reduction as a surgical treatment for patellar fractures.
Long-Term Use of Antiplatelet Therapy in Real-World Patients with Acute Myocardial Infarction: Insights from the PIPER Study
Authors: Degli Esposti Luca , Perrone Valentina , Veronesi Chiara , Buda Stefano , Rossini Roberta ,   on Behalf of a LHUs Group
Published: December 2018

The aim of this study was to assess long-term drug adherence and prognosis in real-world patients discharged on dual-antiplatelet therapy (DAPT) after acute myocardial infarction (AMI). A retrospective cohort analysis using administrative databases kept by eight local health units was performed. DAPT exposure (defined as ≥ 2 prescriptions), adherence, and the occurrence of major adverse events (MACE) were analyzed during a 36-month follow-up. The analysis included 11,101 patients who were discharged alive with a primary diagnosis of AMI. Of these, 5,919 patients (53.31%) were discharged on DAPT without a diagnosis of cancer or anemia, without transient DAPT discontinuation, and represented the study population. DAPT discontinuation occurred in 2,200 patients (37.2%) and in 1,995 (33.7%) after the first 6 and 12 months, respectively, whereas 423 patients (7.1%) were still on DAPT after 36 months. Patients who maintained DAPT up to 12 months had a significantly lower overall mortality, compared with patients who discontinued DAPT after 6 months. Exposure to DAPT at 3 years was associated with reduced all-cause mortality (hazard ratio [HR]: 0.067, 95% confidence interval [CI]: 0.027–0.162, p < 0.001) and reduced recurrent AMI (HR: 0.02, 95% CI: 0.003–0.173, p < 0.001). In conclusion, this study shows that prolonged DAPT over 12 months is maintained in a relevant number of patients after AMI. However, adherence to antiplatelet therapy in first 12 months after AMI is still unsatisfactory and efforts to enhance patients' compliance are warranted. Exposure to prolonged DAPT at 3 years seems to be associated with a significant reduction in all-cause mortality and AMI.
Pilot Study of Pharyngoesophageal Dysmotility Mechanisms in Dysphagic Infants of Diabetic Mothers
Authors: Malkar Manish B. , Viswanathan Sreekanth K. , Jadcherla Sudarshan R.
Published: December 2018

Objective Swallowing difficulties are common in infants of diabetic mothers (IDM) and mechanisms are unclear. We tested the hypothesis that pharyngoesophageal motility reflexes are distinct in IDMs compared with healthy controls in a pilot study.

Study Design Basal and adaptive pharyngoesophageal motility characteristics of 20 dysphagic IDMs and 10 controls were studied using purpose-built micromanometry system.

Results During basal swallows, IDMs had lower frequency of deglutition apneas (62.5 vs. 95.4%) and longer active upper esophageal sphincter (UES) relaxation duration (0.8 ± 0.1 vs. 0.4 ± 0.1 second), whereas during adaptive swallows, IDMs had longer response latency to esophageal peristalsis onset (24.4 ± 2.1 vs. 9.7 ± 2.9 seconds) and longer lower esophageal sphincter nadir duration (28.9 ± 3.2 vs. 12.9 ± 4.6) (all p < 0.05) compared with controls. Nine in the IDM group needed gastrostomy feeding tube at hospital discharge versus none in controls.

Conclusion Feeding difficulties in IDMs are likely to be associated with maladapted or maldeveloped vagal neuropathy mechanisms manifesting as dysregulation of pharyngeal–airway interactions, longer active UES relaxation response, delays in the activation of esophageal contractile apparatus during peristalsis, and prolonged inhibition at the gastroesophageal junction.
Is Metabolic Screening Necessary in Children with Autism Spectrum Disorder? A Mini Review
Authors: Gogou Maria , Evangeliou Athanasios
Published: December 2018

Autism spectrum disorder is a clinically heterogeneous entity with no known specific cause. A variety of inborn errors of metabolism include autistic-like phenotypes in their clinical manifestations. As targeted therapies for many of these errors exist, a question arises whether a routine metabolic screening in all children with autism should be performed. According to current literature, a metabolic workup should not be considered in children with nonsyndromic autism as a first-line investigation. However, detailed cost–benefit analyses are needed to investigate the benefit of a targeted screening of treatable metabolic errors compared with the total financial burden of autism.
Analysis of elastic incoherent neutron scattering data beyond the Gaussian approximation
Authors: Zeller D. , Telling M. T. F. , Zamponi M. , García Sakai V. , Peters J.
Published: December 2018

This work addresses the use of the Gaussian approximation as a common tool to extract atomic motions in proteins from elastic incoherent neutron scattering and whether improvements in data analysis and additional information can be obtained when going beyond that. We measured alpha-lactalbumin with different levels of hydration on three neutron backscattering spectrometers, to be able to resolve a wide temporal and spatial range for dynamics. We demonstrate that the Gaussian approximation gives qualitatively similar results to models that include heterogeneity, if one respects a certain procedure to treat the intercept of the elastic intensities with the momentum transfer axis. However, the inclusion of motional heterogeneity provides better fits to the data. Our analysis suggests an approach of limited heterogeneity, where including only two kinds of motions appears sufficient to obtain more quantitative results for the mean square displacement. Finally, we note that traditional backscattering spectrometers pose a limit on the lowest accessible momentum transfer. We therefore suggest that complementary information about the spatial evolution of the elastic intensity close to zero momentum transfer can be obtained using other neutron methods, in particular, neutron spin-echo together with polarization analysis.
Propensity for spontaneous relaxor-ferroelectric transition in quenched (Na1/2Bi1/2)TiO3-BaTiO3 compositions
Authors: K. V. Lalitha , Koruza Jurij , Rödel Jürgen
Published: December 2018

Recently, quenching lead-free non-ergodic relaxor Na1/2Bi1/2TiO3-BaTiO3 (NBT-BT) materials has been reported to increase the thermal depolarization temperature and enhance the lattice distortion. Driven by the conjecture that enhanced lattice distortion is typically associated with the onset of ferroelectric order, two non-ergodic relaxor NBT-BT compositions at the morphotropic phase boundary were investigated. As evident from the temperature-dependent permittivity, both compositions exhibit a stabilization of ferroelectric order upon quenching. An increase in the depolarization temperature by 40–60 °C is observed. Moreover, the composition with higher tetragonality undergoes a spontaneous relaxor-ferroelectric transition upon quenching. Annealing in oxygen atmosphere is shown to revert back the quenching-induced ferroelectric order to the relaxor state.
Surface reconstruction amendment to the intrinsic sampling method
Authors: Longford Francis G. J. , Essex Jonathan W. , Skylaris Chris-Kriton , Frey Jeremy G.
Published: December 2018

The intrinsic sampling method (ISM) is a powerful tool that allows the exploration of interfacial properties from molecular simulations by fitting a function that represents the local boundary between two phases. However, owing to the non-physical nature of an “intrinsic” surface, there remains an ambiguity surrounding the comparison of theoretical properties with the physical world. It is therefore important that the ISM remains internally consistent when reproducing simulated properties which match experiments, such as the surface tension or interfacial density distribution. We show that the current ISM procedure causes an over-fitting of the surface to molecules in the interface region, leading to a biased distribution of curvature at these molecular coordinates. We assert that this biased distribution is a cause of the disparity between predicted interfacial densities upon convolution to a laboratory frame, an artefact which has been known to exist since the development of the ISM. We present an improvement to the fitting procedure of the ISM in an attempt to alleviate the ambiguity surrounding the true nature of an intrinsic surface. Our “surface reconstruction” method is able to amend the shape of the interface so as to reproduce the global curvature distribution at all sampled molecular coordinates. We present the effects that this method has on the ISM predicted structure of a simulated Lennard-Jones fluid air-liquid interface. Additionally, we report an unexpected relationship between surface thermodynamic predictions of our reconstructed ISM surfaces and those of extended capillary wave theory, which is of current interest.
Does capillary evaporation limit the accessibility of nonaqueous electrolytes to the ultrasmall pores of carbon electrodes?
Authors: Liu Kun , Zhang Pengfei , Wu Jianzhong
Published: December 2018

Porous carbons have been widely utilized as electrode materials for capacitive energy storage. Whereas the importance of pore size and geometry on the device performance has been well recognized, little guidance is available for identification of carbon materials with ideal porous structures. In this work, we study the phase behavior of ionic fluids in slit pores using the classical density functional theory. Within the framework of the restricted primitive model for nonaqueous electrolytes, we demonstrate that the accessibility of micropores depends not only on the ionic diameters (or desolvation) but also on their wetting behavior intrinsically related to the vapor-liquid or liquid-liquid phase separation of the bulk ionic systems. Narrowing the pore size from several tens of nanometers to subnanometers may lead to a drastic reduction in the capacitance due to capillary evaporation. The wettability of micropores deteriorates as the pore size is reduced but can be noticeably improved by raising the surface electrical potential. The theoretical results provide fresh insights into the properties of confined ionic systems beyond electric double layer models commonly employed for rational design/selection of electrolytes and electrode materials.
Introduction to Islamic tourism.
Authors: Jamal A. , Raj R. , Griffin K. A.
Published: December 2018

This chapter defines Islamic tourism and presents an overview of the book's chapters.
Islamic customer relationship marketing (ICRM) and inspirations for religious tourism.
Authors: Kawsar M. J. , Rashid T.
Published: December 2018

The aim of this chapter is to explain and expand the understanding of Islamic customer relationship marketing (ICRM) and its factors for the purpose of religious tourism business. An extensive literature review of various business disciplines, including marketing, relationship marketing, customer relationship marketing, Islamic marketing, religious marketing and religious tourism, is presented in this chapter.
The impact of Umrah quality attributes on religious tourist loyalty in Saudi Arabia.
Authors: Ibrahim Alsini Ibrahim Alsini , Erdogan Ekiz Erdogan Ekiz , Kashif Hussain Kashif Hussain
Published: December 2018

The purpose of this chapter is to elaborate on how quality attributes for tourism activities are linked with tourist loyalty for a religious destination. The chapter reports findings of a research study that assessed Umrah quality attributes as presented in four dimensions (Islamic life and belief, Umrah package services, Umrah destination quality and religious tourist loyalty). These attributes are frequently used by researchers when investigating the quality of experience and loyalty and this chapter utilizes them to gauge religious tourists' perceptions after performing Umrah in Makkah, Saudi Arabia.
Religious tourism in the Sultanate of Oman: the potential for mosque tourism to thrive.
Authors: Kessler K. , Raj R.
Published: December 2018

The purpose of this chapter is to present religious tourism in the Sultanate of Oman and to determine the potential of mosque tourism as a means to contribute towards visitors' cultural experience enrichment. The chapter presents and discusses a classification of Oman's religious sites, including places of worship, tombs or graves of leading religious figures, sites where significant religious personalities lived or died, and sites commemorating specific religious events.
Battlefield tourism: the potential of Badr, Uhud and the Trench (Khandaq) battles for Islamic tourism.
Authors: Akbulut O. , Ekİn Y.
Published: December 2018

This chapter discusses the role of battlefield tourism within the context of Islamic tourism. Drawing insights from dark and heritage tourism literature, the chapter discusses why people are interested in visiting historical sites associated with famous battles. It then introduces three key battles in Saudi Arabia that have very high significance within the religion of Islam. The chapter finally discusses implications for Islamic tourism.
Tablighi Jamaat: a multidimensional movement of religious travellers.
Authors: Abbasi A. S.
Published: December 2018

Tablighi Jamaat is a voluntary mass movement that preaches Islamic teachings, mainly of the Deobandi school of thought, in the Indian subcontinent. This chapter aims to contribute to the religious tourism literature by discussing the transformative nature and role of Tablighi Jamaat within the context of Islamic tourism. To achieve this aim, the chapter provides a brief introduction to Tablighi Jamaat, briefly highlighting its history. It then provides an opportunity to the reader to understand the structure of this mass mobilization of human and other resources through religious travelling, the underlying principles and activities, mechanism of training and development of devotees, and the monitoring of performance and roles of both genders during practical involvements in activities of Tablighi Jamaat. In doing so, the chapter points to the significant transformative experiences that followers experience over an extended period of time. The implications of the movement for the Islamic tourism industry are also discussed, including its economic impact.
Supplemental feeding of phospholipid-enriched alkyl phospholipid from krill relieves spontaneous atopic dermatitis and strengthens skin intercellular lipid barriers in NC/Nga mice
Authors: Watanabe Nana , Suzuki Takuya , Yamazaki Yuya , Sugiyama Kozue , Koike Seiji , Nishimukai Megumi
Published: December 2018

Plasmalogen (Pls) is a glycerophospholipid derived from alkyl phospholipid (Alk) with antioxidant functions in vivo. The present study investigated the effects of ether phospholipids, such as Pls and Alk, on intercellular lipid barriers in the skin of NC/Nga mice, a model of atopic dermatitis (AD). NC/Nga mice fed Alk showed increased plasma levels of Alk and Pls. The AD-related changes in ceramide composition in the skin were abrogated by oral administration of Alk. Moreover, Alk suppressed skin inflammation in AD mice. These results indicate that Alk partially fortifies the stratum corneum lipid barrier and may be an effective treatment for AD.

Abbreviations: Pls: plasmalogen; PlsCho: choline plasmalogen; PlsEtn: ethanolamine plasmalogen; Alk: alkyl phospholipid; TJ: tight junction; FA: fatty acid; AD: atopic dermatitis; SO: soybean oil; FO: fish oil; DHA: docosahexaenoic acid; EPA: eicosapentaenoic acid; TG: triglyceride; PL: phospholipid; RF: retention factor; AlkCho: choline-type alkyl phospholipid; AlkEtn: ethanolamine-type alkyl phospholipid; LC-MS/MS: liquid chromatography-tandem mass spectrometry; FAR1: fatty acyl-coenzyme (Co)A reductase 1
Attenuation and reflection measurements for coaxials at 100 MHz, 1 GHz and 10 GHz - Type N Connector (AFRIMETS.EM.RF-S1)
Authors: Magagula L , Mallat A , Fezai N , Sallam A R
Published: December 2018

A supplementary comparison of two fixed attenuators (3 dB HP 8491B and 20 dB HP 8491B) for RF attenuation and two mismatched loads (Maury 2562C and Maury 2561A) for voltage reflection coefficient was carried out between three AFRIMETS members namely NMISA (South Africa, the pilot laboratory), DEFNAT (Tunisia) and NIS (Egypt). The motivation for the comparison was to verify the consistency and equivalence of RF attenuation and reflection measurements between the participants. The agreement between the participants' measurements was good as evidenced by the normalised error, which was less than unity for all the specified frequency points for both the attenuation measurements and voltage reflection coefficient measurements.

KEY WORDS FOR SEARCH

attenuation; measurement methods; reference value; reflection

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.

The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
How Did The American Recovery and Reinvestment Act Affect the Material Well‐Being of SNAP Participants? A Distributional Approach
Authors: Valizadeh Pourya , Smith Travis A
Published: December 2018

Money‐metric welfare, or material well‐being, can be defined by household expenditure. We find that the 2009 ARRA benefit increase improved material well‐being at all expenditure levels, which is interpreted as a first‐order policy improvement. The adverse effects of the 2013 benefit cuts, however, were concentrated among the most disadvantaged SNAP subpopulations. These effects are almost entirely driven by changes in food rather than nonfood spending. The asymmetric shift in the distribution of well‐being speaks to the resource management skills and coping strategies among the low‐income households, especially the most disadvantaged, and calls for improved education on budgeting skills.
Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women
Authors: Saquib Nazmus , Brunner Robert , Desai Manisha , Kroenke Candyce , Martin Lisa W , Daviglus Martha , Allen Norrina B , Robinson Jennifer , Tindle Hilary , Stefanick Marcia L
Published: December 2018

Background

physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death.

Methods

in the Women’s Health Initiative Observational Study, 48,906 women (50–79 years) had complete data at baseline on physical and mental health (assessed with Short Form-36) and key covariates. Changes in self-reported physical and mental health were calculated between baseline and year 3. Incident CVD and death between year 3 and end of the study were verified with medical records.

Results

over a median 8.2-year follow-up, 2,319 women developed CVD, and 1,571 women died, including 361 CVD deaths. Women with continued poor health and those with worsened health had significantly increased risk of CVD incidence, CVD-specific death and all-cause death relative to women with continued good health. Both major and minor declines in physical health were associated with an increased risk of these outcomes relative to women with no change in physical health. Only major declines in mental health were associated with poor prognosis.

Conclusions

changes in physical and mental health over 3 years were independently associated with subsequent CVD events.
Systematic characterization and prediction of post-translational modification cross-talk between proteins
Authors: Huang Rongting , Huang Yuanhua , Guo Yubin , Ji Shangwei , Lu Ming , Li Tingting
Published: December 2018

Motivation

Protein post-translational modifications (PTMs) regulate a wide range of cellular protein functions. Many PTM sites from the same (intra) or different (inter) proteins often cooperate with each other to perform a function, which is defined as PTM cross-talk. PTM cross-talk within proteins attracted great attentions in the past a few years. However, the inter-protein PTM cross-talk is largely under studied due to its large protein pair space and lack of a gold standard dataset, even though the PTM interplay between proteins is a key element in cell signaling and regulatory networks.

Results

In this study, 199 inter-protein PTM cross-talk pairs in 82 pairs of human proteins were collected from literature, which to our knowledge is the first effort in compiling such dataset. By comparing with background PTM pairs from the same protein pairs, we found that inter-protein cross-talk PTM pairs have higher sequence co-evolution at both PTM residue and motif levels. Also, we found that cross-talk PTMs have higher co-modification across multiple species and 88 human tissues or conditions. Furthermore, we showed that these features are predictive for PTM cross-talk between proteins, and applied a random forest model to integrate these features with achieving an area under the receiver operating characteristic curve of 0.81 in 10-fold cross-validation, prevailing over using any single feature alone. Therefore, this method would be a valuable tool to identify inter-protein PTM cross-talk at proteome-wide scale.

Availability and implementation

A web server for prioritization of both intra- and inter-protein PTM cross-talk candidates is at http://bioinfo.bjmu.edu.cn/ptm-x/. Python code for local computer is also freely available at https://github.com/huangyh09/PTM-X.

Supplementary information

Supplementary data are available at Bioinformatics online.
Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences
Authors: Rosenberg Noah A , Edge Michael D , Pritchard Jonathan K , Feldman Marcus W
Published: December 2018

Recent analyses of polygenic scores have opened new discussions concerning the genetic basis and evolutionary significance of differences among populations in distributions of phenotypes. Here, we highlight limitations in research on polygenic scores, polygenic adaptation and population differences. We show how genetic contributions to traits, as estimated by polygenic scores, combine with environmental contributions so that differences among populations in trait distributions need not reflect corresponding differences in genetic propensity. Under a null model in which phenotypes are selectively neutral, genetic propensity differences contributing to phenotypic differences among populations are predicted to be small. We illustrate this null hypothesis in relation to health disparities between African Americans and European Americans, discussing alternative hypotheses with selective and environmental effects. Close attention to the limitations of research on polygenic phenomena is important for the interpretation of their relationship to human population differences.
The Changing Relationship Between Partnership Status and Loneliness: Effects Related to Aging and Historical Time
Authors: Böger Anne , Huxhold Oliver
Published: December 2018

Objectives

Partnership status is a central predictor of loneliness. The strength of this predictive relationship, however, may decrease in the course of aging and over historical time. Moreover, there may be aging-related and historical changes in the satisfaction with partnership and singlehood.

Method

Longitudinal data from the German Ageing Survey (DEAS) assessed in 2008 and 2014 (N = 6,188, age range: 40–85 years) was analyzed with multigroup structural equation models to disentangle aging-related and historical changes in the relationship of partnership status and loneliness and in the average level of satisfaction with partnership and singlehood.

Results

With advancing age, partnership status became less predictive of loneliness and the satisfaction with being single increased. Among later-born cohorts, the association between partnership status and loneliness was less strong than among earlier-born cohorts. Later-born single people were more satisfied with being single than their earlier-born counterparts. There was no indication for an aging-related or historical decrease in partnership satisfaction.

Discussion

The relevance of partnership status as a predictor of social well-being is neither universal nor stable but appears to change in the course of aging and across historical time.
Sharing-Dominant Logic? Quantifying the Association between Consumer Intelligence and Choice of Social Access Modes
Authors: Aspara Jaakko , Wittkowski Kristina
Published: December 2018

With sharing economy and access-based consumption, consumers increasingly access goods through social access modes other than private ownership—such as co-ownership, leasing, or borrowing. Prior research focuses on consumers’ attitudinal motivations and consumption-cultural use experiences pertaining to such social exchange–based access modes. In so doing, prior research has overlooked the influence that consumers’ fundamental, even biologically shaped, cognitive traits may have on their choice of access modes. To fill this research gap, this study analyzes a data set of more than 30,000 new car registrations by male consumers in Finland, including cognitive test data from the Finnish Defense Forces and covariates from other governmental sources. The field data suggests that consumers’ intelligence scores and their choice to co-own and lease their cars are positively associated. Econometric evidence further suggests that the association between intelligence and choice of social exchange–based access modes can be explained by intelligent consumers’ higher social trust in people and institutions, as well as two circumstantial mechanisms: their financial standing and tendency to seek savings. The findings from the field data are supported by an additional survey study (n = 460). Implications for the evolution of markets and consumption, as well as human intelligence and cooperation, are discussed.
DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor
Authors: Schabla N Max , Mondal Koushik , Swanson Patrick C
Published: December 2018

Cullin-RING ligases (CRLs) comprise a large group of modular eukaryotic E3 ubiquitin ligases. Within this family, the CRL4 ligase (consisting of the Cullin4 [CUL4] scaffold protein, the Rbx1 RING finger domain protein, the DNA damage-binding protein 1 [DDB1], and one of many DDB1-associated substrate receptor proteins) has been intensively studied in recent years due to its involvement in regulating various cellular processes, its role in cancer development and progression, and its subversion by viral accessory proteins. Initially discovered as a target for hijacking by the human immunodeficiency virus accessory protein r, the normal targets and function of the CRL4 substrate receptor protein DDB1–Cul4-associated factor 1 (DCAF1; also known as VprBP) had remained elusive, but newer studies have begun to shed light on these questions. Here, we review recent progress in understanding the diverse physiological roles of this DCAF1 in supporting various general and cell type-specific cellular processes in its context with the CRL4 E3 ligase, as well as another HECT-type E3 ligase with which DCAF1 also associates, called EDD/UBR5. We also discuss emerging questions and areas of future study to uncover the dynamic roles of DCAF1 in normal physiology.