bluuebunny/crossref_metadata_2025 huggingface dataset:
The Dilemma in Treatment of hemodialysis patients with catheter-induced right atrial thrombi (CRAT): A case report
Authors: Ansari Aval Zahra , Baghaei Ramin , Khaheshi Isa , Alavi-Moghaddam Aida
Published: May 2017

Catheter-induced right atrial thrombi (CRAT) is a serious complication of central venous catheterization. Herein we report a case of large hypermobile right atrial thrombi in a 57-year-old man with hemodialysis catheter in the right internal jugular vein.
Der Einfluss spiritueller Übungen im Sinne der ignatianischen Lehre auf das religiös-spirituelle Wohlbefinden dermatologischer Patienten und Patientinnen
Authors: Aberer Elisabeth , Sallinger Anna , Pilch Michaela , Scharf Sabina , Lukanz Martin , Fink-Puches Regina , Wutte Nora , Glawischnig-Goschnik Monika , Unterrainer Human-Friedrich
Published: May 2017

In der Vergangenheit haben Studien gezeigt, dass sich Interventionen bei chronisch Kranken und Krebspatient/-innen positiv auf die religiös-spirituelle (r/s) Befindlichkeit und die Krankheitsverarbeitung auswirken können. Es gibt jedoch keine standardisierten Vorgaben für r/s Interventionen. In einer Pilotstudie führten wir bei 10/24 dermatologischen Patient/-innen religiös-spirituelle Interventionen durch, während 7 Patient/-innen einen Fachvortrag mit anschließendem Telefoninterview erhielten. Die Kontrollgruppe (n=7) erhielt keine Intervention. Alle Patient/-innen wurden mittels des Multidimensionalen Inventars zum religiös/spirituellen Befinden (MI-RSB) sowie mit dem SF-36 zur Lebensqualität zweimalig befragt.

Die r/s Interventionen fanden einmal pro Woche innerhalb von 2 Monaten insgesamt achtmal statt, dauerten 90 Minuten und wurden von einer christlichen Theologin vorgenommen, die Erfahrung in Exerzitien und spiritueller Begleitung hat. Elemente der Übungen waren Meditation, Rituale, Lieder, Erfahrungsaustausch, Geschichten und Impulse zu Themen, die für Sinnstiftung und die Tiefendimensionen des Lebens relevant sind. Diese Interventionen stützten sich auf Aspekte der ignatianischen Spiritualität und auf Grundfragen christlicher Spiritualität.

Während jede Art von Zuwendung für die Patient/-innen eine Zunahme der Lebensqualität bedeutet, nimmt durch die r/s Interventionen die transzendente Hoffnung signifikant zu. Die Auswirkung unserer r/s Intervention könnte Anlass sein, derartige Interventionen weiterzuentwickeln und in größer angelegten Multicenter-Studien zu testen.
Multi-Component Generalizations of Two Hierarchies Related to the Yajima-Oikawa Hierarchy
Authors: Li Nianhua , Li Hongmin
Published: May 2017

We present a multi-component modified Yajima-Oikawa hierarchy and a multi-component Novikov hierarchy. We get generalized Hamiltonian structures for the two hierarchies with the aid of trace identity.
Analysis of Cracking Resistance of Bituminous Mixtures Under Monotonic and Cyclic Loads
Authors: Pérez-Jiménez F. E. , Miró R. , Martínez A. H. , Botella R.
Published: May 2017

Although cracking resistance is one of the most important properties affecting the durability of asphalt mixtures, this property is often not considered as a requirement in the mixture design stage, and the bitumen content is determined from other properties (voids content, permanent deformation, or water sensitivity, etc…). The effect of bitumen content on the cracking resistance of an asphalt concrete mixture (type AC) was analyzed in this paper by means of different types of tests. Firstly, a cyclic strain sweep test (EBADE test) was used to obtain the evolution of the complex modulus and dissipated energy density with the number of cycles as well as the failure strain. Results from a previous research study helped approximate the fatigue laws of the mixtures studied, providing insight into the effect of binder content on the fatigue life of the mixtures manufactured with 3, 4, 5, and 6 % of binder by mixture mass. Secondly, a direct tensile monotonic test (Fénix test) was used to determine the strength and fracture energy of the mixture. The mixture with the 5 % binder content exhibited better results in all tests, indicating that this value would be the optimum binder content as it showed good consistency between the cyclic and monotonic tests employed.
Development and Initial Validation of an Inconsistent Responding Scale for the Youth Psychopathic Traits Inventory
Authors: Penson Brittany N. , Ruchensky Jared R. , Edens John F. , Donnellan M. Brent , Vaughn Michael G. , Eisenbarth Hedwig
Published: May 2017

The Youth Psychopathic Traits Inventory (YPI) is widely used in research, but there currently exist no means to identify potentially invalid protocols resulting from careless or random responding. We describe the development of an inconsistent responding scale for the YPI using three archival samples of youths, including two from the United States (juvenile justice and middle school) and one from Germany (vocational training school). We first identified pairs of correlated YPI items and then created a total score based on the sum of the absolute value of the differences for each item pair. The resulting scale strongly differentiated between genuine protocols and randomly generated YPI data (n = 1,000) across samples (AUC values = .88−.92). It also differentiated between genuine protocols and those same protocols after 50% of the original YPI items were replaced with random data (AUCs = .77−.84). Scores on this scale also demonstrated fairly consistent patterns of association with theoretically relevant correlates.
Borderline Personality Disorder Features and Sensitivity to Injustice
Authors: Lis Stefanie , Schaedler Anna , Liebke Lisa , Hauschild Sophie , Thome Janine , Schmahl Christian , Stahlberg Dagmar , Kleindienst Niko , Bohus Martin
Published: May 2017

Hypersensitivity to injustice has been proposed to contribute to interpersonal dysfunction in borderline personality disorder (BPD). We investigated whether BPD features are related to sensitivity to injustice and whether justice sensitivity mediates the relationship between BPD features and aggressive behavior. In an online survey, subjects reported justice sensitivity from the perspective of a victim, an observer, a beneficiary, and a perpetrator as well as BPD features and their own aggressive behavior. Justice sensitivity was higher in participants with a clinically relevant degree of BPD features when they evaluated injustice from the perspective of a victim or an observer. Victim sensitivity partially mediated the relationship between BPD features and the frequency of aggressive behavior. The present study provides first data on the important role of sensitivity to injustice in those with marked BPD features. Particularly, victim sensitivity with its close link to angry reactions may contribute to interpersonal problems in BPD.
Ireland in Late Antiquity
Authors: Johnston Elva
Published: May 2017

It is often assumed that Ireland entered recorded history with the emergence of organized Christianity on the island at some point in the fourth or fifth century C.E. This assumption has meant that the histories of late antique and early medieval Ireland are primarily viewed through the lens of conversion. Religious identities, frequently imagined as a binary opposition of “Christian” and “pagan,” have been a dominant historiographical focus. This essay argues that it is more fruitful to examine the relationship between Ireland and its neighbors from c. 150–c. 550 C.E. through a frontier dynamic, a dynamic in which religious identity was but one factor among many. By recasting the Irish experience in this way, it is possible to take a more comparative approach which cuts against the grain of Irish exceptionalism. Moreover, situating Ireland within the scholarly discourse of late antiquity allows for a new and nuanced understanding of the social and religious changes that characterized this period on the island.
Constantine in the Chronicle of Seert
Authors: Wood Philip
Published: May 2017

This article analyses the reception of the story of Constantine in Iraqi Christian circles in the ninth and tenth centuries. It situates the use of the story against the broader historiographic context in which the history of the Roman church was imported wholesale into Iraq in the sixth century to buttress its identity as an orthodox church. It argues that the legacy of Eusebius was respected but not followed in its details. Instead, the memory of Constantine and his family was dominated by the Doctrina Addai and the Julian Romance, pseudo-histories composed in Syriac in Edessa in the fifth and sixth centuries. Within an Islamicate environment, Constantine was remembered chiefly for his role in establishing a Nicene orthodoxy, which was shared by all major Christian confessions in the caliphate, and for his role in the cult of the True Cross, a strong symbol that continued to divide Christians and Muslims.
The Riddle of the Nablus Collection
Authors: Yaceczko Lionel
Published: May 2017

The Nablus Collection is a previously-unpublished hoard of imperial Roman bronze coins from the Tetrarchic Period (294-318) housed at the Catholic University of America.

The Collection is comparable to many other, similar hoards and confirms common trends such as weight, time span, and inflation during the period. One programmatic weight reduction, in the year 307/308, is well documented in the Collection, and the hoard further substantiates a lesser-known weight reduction in the year 312 for which no material evidence had as yet been discovered. The Collection, however, differs from other hoards in several remarkable ways, raising questions that require creative hypotheses. The mint distribution supported by comparable hoards of the period contrasts strikingly with that of the Collection, which evidences a balance of eastern and western mints peculiar for the period. The hoard testifies to the economic rise of a frontier colony which by the 320s had become an established community with its own bishop and the importance to attract a flow of foreign coin from across the Empire. The Collection adds a small piece to the story of that turbulent period when Constantine marched from York, crossed the Empire, and finally settled in the East.
Two Loci Contribute Epistastically to Heterospecific Pollen Rejection, a Postmating Isolating Barrier Between Species
Authors: Hamlin Jennafer A P , Sherman Natasha A , Moyle Leonie C
Published: May 2017

Recognition and rejection of heterospecific male gametes occurs in a broad range of taxa, although the complexity of mechanisms underlying these components of postmating cryptic female choice is poorly understood. In plants, the arena for postmating interactions is the female reproductive tract (pistil), within which heterospecific pollen tube growth can be arrested via active molecular recognition and rejection. Unilateral incompatibility (UI) is one such postmating barrier in which pollen arrest occurs in only one direction of an interspecific cross. We investigated the genetic basis of pistil-side UI between Solanum species, with the specific goal of understanding the role and magnitude of epistasis between UI QTL. Using heterospecific introgression lines (ILs) between Solanum pennellii and S. lycopersicum, we assessed the individual and pairwise effects of three chromosomal regions (ui1.1, ui3.1, and ui12.1) previously associated with interspecific UI among Solanum species. Specifically, we generated double introgression (‘pyramided’) genotypes that combined ui12.1 with each of ui1.1 and ui3.1, and assessed the strength of UI pollen rejection in the pyramided lines, compared to single introgression genotypes. We found that none of the three QTL individually showed UI rejection phenotypes, but lines combining ui3.1 and ui12.1 showed significant pistil-side pollen rejection. Furthermore, double ILs (DILs) that combined different chromosomal regions overlapping ui3.1 differed significantly in their rate of UI, consistent with at least two genetic factors on chromosome three contributing quantitatively to interspecific pollen rejection. Together, our data indicate that loci on both chromosomes 3 and 12 are jointly required for the expression of UI between S. pennellii and S. lycopersicum, suggesting that coordinated molecular interactions among a relatively few loci underlie the expression of this postmating prezygotic barrier. In addition, in conjunction with previous data, at least one of these loci appears to also contribute to conspecific self-incompatibility (SI), consistent with a partially shared genetic basis between inter- and intraspecific mechanisms of postmating prezygotic female choice.
Definition of a RACK1 Interaction Network in Drosophila melanogaster Using SWATH-MS
Authors: Kuhn Lauriane , Majzoub Karim , Einhorn Evelyne , Chicher Johana , Pompon Julien , Imler Jean-Luc , Hammann Philippe , Meignin Carine
Published: May 2017

Receptor for Activated protein C kinase 1 (RACK1) is a scaffold protein that has been found in association with several signaling complexes, and with the 40S subunit of the ribosome. Using the model organism Drosophila melanogaster, we recently showed that RACK1 is required at the ribosome for internal ribosome entry site (IRES)-mediated translation of viruses. Here, we report a proteomic characterization of the interactome of RACK1 in Drosophila S2 cells. We carried out Label-Free quantitation using both Data-Dependent and Data-Independent Acquisition (DDA and DIA, respectively) and observed a significant advantage for the Sequential Window Acquisition of all THeoretical fragment-ion spectra (SWATH) method, both in terms of identification of interactants and quantification of low abundance proteins. These data represent the first SWATH spectral library available for Drosophila and will be a useful resource for the community. A total of 52 interacting proteins were identified, including several molecules involved in translation such as structural components of the ribosome, factors regulating translation initiation or elongation, and RNA binding proteins. Among these 52 proteins, 15 were identified as partners by the SWATH strategy only. Interestingly, these 15 proteins are significantly enriched for the functions translation and nucleic acid binding. This enrichment reflects the engagement of RACK1 at the ribosome and highlights the added value of SWATH analysis. A functional screen did not reveal any protein sharing the interesting properties of RACK1, which is required for IRES-dependent translation and not essential for cell viability. Intriguingly however, 10 of the RACK1 partners identified restrict replication of Cricket paralysis virus (CrPV), an IRES-containing virus.
Building Ultra-High-Density Linkage Maps Based on Efficient Filtering of Trustable Markers
Authors: Ronin Yefim I , Mester David I , Minkov Dina G , Akhunov Eduard , Korol Abraham B
Published: May 2017

This study concerns building high-density genetic maps in situations with intrachromosomal recombination rate heterogeneity and differences in genotyping

The study is focused on addressing the problem of building genetic maps in the presence of ∼103–104 of markers per chromosome. We consider a spectrum of situations with intrachromosomal heterogeneity of recombination rate, different level of genotyping errors, and missing data. In the ideal scenario of the absence of errors and missing data, the majority of markers should appear as groups of cosegregating markers (“twins”) representing no challenge for map construction. The central aspect of the proposed approach is to take into account the structure of the marker space, where each twin group (TG) and singleton markers are represented as points of this space. The confounding effect of genotyping errors and missing data leads to reduction of TG size, but upon a low level of these effects surviving TGs can still be used as a source of reliable skeletal markers. Increase in the level of confounding effects results in a considerable decrease in the number or even disappearance of usable TGs and, correspondingly, of skeletal markers. Here, we show that the paucity of informative markers can be compensated by detecting kernels of markers in the marker space using a clustering procedure, and demonstrate the utility of this approach for high-density genetic map construction on simulated and experimentally obtained genotyping datasets.
Esquizofrenia y funcionamiento: medición con la escala breve de evaluación del funcionamiento y correlación con los años de enfermedad
Authors: Osorio-Martínez Miriam L.
Published: May 2017

Introducción. La esquizofrenia se asocia a deterioro de las capacidades de la persona, en varios ámbitos de su vida, en forma progresiva. Sin embargo, este hecho ha sido poco estudiado en nuestra población. Objetivo. Identificar la afectación en el funcionamiento según tiempo con esquizofrenia. Diseño. Estudio analítico correlacional, diseño observacional transversal. Lugar. Hospital Hermilio Valdizán, Lima, Perú. Participantes. Pacientes diagnosticados de esquizofrenia atendidos ambulatoriamente. Intervenciones. Entrevista y aplicación de escalas, a 136 pacientes, en 4 grupos de 34, según tiempo de enfermedad. El análisis se efectuó con las pruebas de t-student, Kruskall-Wallis, U de Mann Whitney y Correlación de Spearman, con intervalo de confianza 95%, p< 0,05. Principales medidas de resultados. Medida del funcionamiento empleando la escala breve de evaluación del funcionamiento (FAST) y medida de síntomas psicóticos con escala breve de valoración de síntomas psiquiátricos (BPRS). El puntaje FAST es inversamente proporcional con el funcionamiento. Resultados. El 57% fueron varones, 47,9 % en rango de 21 a 30 años. El puntaje FAST para el grupo menor de 1 año de enfermedad fue 50,2 + 9,3 DE, 1 a 5 años 57,1 + 10,6 DE, 6 a 10 años 59,0 + 9,7 DE, y con más de 10 años de enfermedad 60,2 + 10,1 DE. Se halló diferencia significativa entre el funcionamiento (p <0,005) para el grupo con menos de un año de enfermedad en relación a los otros. Conclusiones. Los pacientes con menos de un año de enfermedad mostraron mejor funcionamiento. Se observó disminución del funcionamiento después del primer año de diagnóstico, indistintamente entre los grupos. Existe la necesidad de empezar estrategias de rehabilitación tempranas.
Evolución del virus dengue en el Ecuador. Período 2000 a 2015
Authors: Real-Cotto Jhony Joe , Regato Arrata Mary Ernestina , Burgos Yépez Virginia Elisa , Jurado Cobeña Eduardo Tarquino
Published: May 2017

Introducción. Actualmente la infección por virus dengue constituye una de las arbovirosis más importantes y de amplia distribución en las regiones tropicales y subtropicales del planeta. Objetivo. Determinar la evolución del virus dengue circulante en el Ecuador durante el periodo 2000 a 2015. Diseño. Estudio no experimental, transversal, de tipo descriptivo y correlacional; Lugar. Unidades de salud del Ecuador. Participantes. Muestras tomadas a sospechosos de dengue con menos de 5 días de iniciada su enfermedad. Resultados. En el año 2000 se tuvo la presencia de los 4 serotipos, con predominio del DEN3 durante 2001 al 2006, coincidentes con los incrementos de casos del 2000, 2001 y 2005; en el año 2004 reapareció el virus DEN1 y los años siguientes su presencia predominó entre 2007 y 2012, coincidiendo con el incremento de casos en el 2010. Del año 2011 al 2015 se presentaron 3 virus circulantes a la vez (DEN1, DEN2 y DEN4), en 2014 y 2015 hubo la presencia del virus DEN3, con predominio del virus DEN2 en 2013 y 2014 y virus DEN1 en 2015; y ha sido la provincia del Guayas la de mayor relación con los virus. Conclusiones. La presencia de varios serotipos de virus dengue circulando a la vez y su permanencia se debería a otros factores que están influenciando en el comportamiento del virus, con una variabilidad de los cuatro serotipos. Se debe fortalecer la vigilancia molecular de la circulación de serotipos, genotipos y linajes del virus dengue.
Derivación y validación de una ecuación para estimar el colesterol ligado a lipoproteínas de baja densidad en una población de Lima, Perú
Authors: Saldaña Orejón Italo Moisés , Benites Ricra Miguel Ángel , Chipana Huallpa Justhin Andrés
Published: May 2017

Introducción. Numerosos estudios han demostrado una fuerte asociación entre el aumento de la concentración sérica del colesterol de las lipoproteínas de baja densidad (LDLc) y la incidencia de la enfermedad coronaria (EC). Objetivos. Derivar y validar la performance de una nueva ecuación para estimar el LDLc. Diseño. Estudio observacional y descriptivo. Institución. Hospital Edgardo Rebagliati Martins, Lima, Perú. Material. Informes de perfil lipídico. Intervenciones. La muestra de 4 644 informes de perfil lipídico extraídos de los archivos del laboratorio central, correspondiente a sujetos de ambos sexos, que presentaban edades entre 18 a 75 años, fue repartida en dos grupos. Del primer grupo conformado por 2 136 informes se derivó la ecuación para estimar el LDLc, mediante análisis de regresión múltiple. El segundo grupo conformado por 2 508 informes sirvieron para validar la performance de la nueva ecuación mediante la comparación con la medida del LDLc por el método directo homogéneo y estimado por la fórmula de Friedewald. Principal medida de resultados. Concentración sérica del LDLc. Resultados. La fórmula de Friedewald y la nueva ecuación infraestimaron el LDLc, obteniéndose sesgos de 14,01 mg/dL y 5,52 mg/dL, respectivamente, con respecto al método directo. Los errores sistemáticos en los tres niveles de decisión clínica para el LDLc resultaron ser mayores para la fórmula de Friedewald (12,6%, 12,0% y 11,7%) comparados a la nueva ecuación (4,2%, 5,7% y 6,7%). El factor de corrección de sesgo, que valora la exactitud, resultó ser más alto y más cerca de la línea de perfecta concordancia para la nueva ecuación, en toda la muestra y cuando esta se estratificó por niveles de triglicéridos. Conclusiones. La nueva ecuación ofrece una mayor exactitud y bajo error analítico comparada a la fórmula de Friedewald para estimar el LDLc, en los tres niveles de decisión clínica y en sueros con diferentes valores de triglicéridos.
Enfoques de aprendizaje y rendimiento académico en estudiantes de medicina del primer año de la Universidad Nacional Mayor de San Marcos
Authors: Barrón Pastor Heli Jaime , Mitma de Barrón Yesica Llimpe
Published: May 2017

Introducción. Cada año, miles de estudiantes de medicina se enfrentan al desafío de superar las asignaturas para adquirir las competencias para sus actividades profesionales. El éxito de la vida estudiantil en camino a la profesión depende de muchos factores incluyendo los enfoques de aprendizaje. Objetivo. Determinar los enfoques de aprendizaje predominantes de los estudiantes de medicina del primer año y su relación con el rendimiento académico. Diseño. Estudio observacional, descriptivo, de corte transversal, cuantitativo. Lugar. Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú. Participantes. Estudiantes de la Facultad de Medicina. Intervenciones. A 130 estudiantes de la Facultad de Medicina matriculados en la asignatura de Biología celular y molecular, se aplicó una versión corta del cuestionario Approaches and Study Skills Inventory for Students (ASSIST) y se evaluó la relación de enfoques de aprendizaje con rendimiento académico. La asociación de las subescalas del cuestionario se evaluó mediante análisis factorial y la consistencia interna mediante análisis alfa de Cronbach. La relación de cada enfoque de aprendizaje y el rendimiento académico se evaluó mediante análisis de regresión. El efecto de la edad, sexo y sus interacciones con cada enfoque de aprendizaje se evaluó con la prueba ANOVA de dos vías. Principales medidas de resultados. Puntaje de los enfoques de aprendizaje profundo, estratégico y superficial. Resultados. El puntaje total de los enfoques de aprendizaje profundo, estratégico y superficial fueron 22,4, 20,4 y 15,4, respectivamente. Hubo correlación significativa entre la puntuación de exámenes teóricos y enfoque estratégico (p=0,004). No se encontraron diferencias con relación a edad y sexo. Conclusiones. El enfoque profundo fue el predominante en estudiantes de medicina del primer año de la Universidad Nacional Mayor de San Marcos. Se encontró correlación significativa entre el enfoque estratégico y el rendimiento académico.
Elaboración de un artículo de reporte de caso clínico o de revisión, en la materia de metodología de la investigación en medicina
Authors: Aguilar-Vargas Esteban , Avilés-Ibarra Oswaldo José , Méndez Nina
Published: May 2017

Introducción. La formación en redacción y metodología de la investigación es importante en la formación médica. En el plan de estudios de la licenciatura en medicina de la universidad marista de Mérida, Yucatán, México, se imparte la materia de metodología de la investigación en el sexto semestre y actualmente involucra la generación de competencias para la comunicación escrita. En el presente artículo, presentamos los resultados obtenidos en el programa académico de la materia, en la cual los alumnos desarrollaron un borrador de artículo académico y posteriormente elaboraron un artículo, para lo cual optaron por un reporte de caso clínico o un artículo de revisión. Métodos. Este es un estudio descriptivo, observacional mediante encuesta a los alumnos. Adicionalmente se analiza los productos académicos derivados del curso que fueron sometidos para su publicación seis meses después de iniciado el curso y las experiencias y percepciones expresadas por los alumnos. Resultados. De una generación de 60 alumnos, 19 (32%) optaron por un manuscrito de reporte de caso clínico y 41 (68%) eligieron un tema de revisión. Un artículo derivado de la materia ha sido publicado, dos de revisión y tres de caso clínico se encuentran ahora bajo revisión. Conclusiones. Los alumnos de pregrado fueron capaces de desarrollar manuscritos de revisión y de reportes de caso clínico de calidad y eligieron el tipo de artículo tomando en cuenta el acceso a los datos, el tiempo requerido y la estructura del manuscrito.
Manifestaciones neurológicas de la infección por el virus zika
Authors: Zunt Joseph R.
Published: May 2017

El virus zika es un flavivirus transmitido a través de la mordedura de mosquito, transfusión de sangre, la relación sexual o de madre a hijo durante la gestación. Aunque las complicaciones neurológicas de la infección por el virus zika son raras, el síndrome de Guillain-Barré (GBS) es la manifestación más común y normalmente se desarrolla poco después de las manifestaciones sistémicas iniciales de la infección por el virus. Este síndrome comienza en las extremidades distales con alteraciones sensoriales simétricas y progresa hasta involucrar la debilidad y la disminución o ausencia de reflejos tendinosos profundos. Los casos graves pueden implicar deterioro respiratorio y cardiovascular, requiriendo atención en una unidad de cuidados intensivos, así como ventilador o soporte circulatorio. Una revisión de 166 casos publicados de GBS asociados con el virus zika se caracteriza por una menor mortalidad que los observados con GBS esporádica, pero los datos son limitados con respecto a resultados a largo plazo. Cuando esté disponible, el tratamiento con IgG intravenoso (IVIg) o plasmaféresis puede reducir la gravedad y duración de los síntomas.
CURING EFFECTS ON THE GROWTH OF LISTERIA MONOCYTOGENES AND ESCHERICHIA COLI O157:H7 IN CAMEL MEAT USING MOST PROBABLE NUMBER-POLYMERASE CHAIN REACTION METHOD
Authors: Reza Gheisari Hamid , Hamzeloo Afshin , Hosseinzadeh Saeid , Basiri Sara
Published: May 2017

MPN-PCR method was used to determine Escherichia coli O157:H7 and Listeria monocytogenes in cured camel meat samples during nine days of storage. The MPN-PCR is based on the combination between the conventional Most Probable Number and the Polymerase Chain Reaction technique targeting the Stx1and Stx2 gene for Ecoli O157:H7 and hlyA gene for L. monocytogenes.Growth of both bacteria in the cured and control experimental groups was initially subjected to a spectrophotometric MPN assay using a microplate reader followed by confirming by two PCR assays. It was shown that in the inoculated samples, the population of both microorganisms was significantly increased at all the test times. However, a significant reduction in the populations of both microorganisms was shown in the cured meat compared to the inoculated -but not- cured group. Our results suggested that curing can improve the microbial quality of camel meat.
Leitura de rótulos de alimentos por frequentadores de um estabelecimento comercial
Authors: Marzarotto Bruna , Alves Márcia Keller
Published: May 2017

Objetivo: Avaliar se os frequentadores de um estabelecimento comercial têm o hábito de ler e se conseguem compreender a rotulagem nutricional dos alimentos.Materiais e Métodos: Estudo transversal, realizado em 2012 e 2013, com 227 indivíduos selecionados e entrevistados aleatoriamente em um estabelecimento comercial alimentício de Caxias do Sul-RS. O questionário aplicado avaliou o nível socioeconômico, hábito e motivo de leitura, principal informação observada, critérios de escolha dos alimentos, entre outros. A associação entre as variáveis foi analisada através do teste qui-quadrado, utilizando o software SPSS versão 19.0.Resultados: A amostra foi formada principalmente por consumidores do gênero feminino, casados, com menos de 30 anos, com ensino superior completo e renda mensal acima de R$1.500,00. A maioria (70%) possui o hábito de leitura e 40,5% o fazem no supermercado. A informação nutricional mais lida é o valor calórico, motivada pela busca por uma alimentação saudável. A internet é a fonte de informação mais utilizada para a busca de conhecimentos sobre alimentação e nutrição. Qualidade e sabor do alimento são os critérios mais destacados pelos clientes na hora da compra do alimento. Entre os entrevistados, 39,2% diz ter 30 minutos para a realização das compras, tempo suficiente para efetuar a leitura dos rótulos. Os indivíduos dizem utilizar as informações encontradas para manter uma alimentação saudável, porém, não acreditam conhecer o suficiente de nutrição.Conclusão: O hábito de leitura está presente entre os entrevistados, que utilizavam a declaração nutricional para orientação alimentar com o objetivo de manter uma dieta saudável. Entretanto, os participantes não acreditam ter conhecimento suficiente de nutrição para a compreensão das informações contidas nos rótulos.
Mortalidade por doença cardíaca hipertensiva nas macrorregiões brasileiras
Authors: Fraga Amanda Silva , De Sá Cloud Kennedy Couto , Tenório Mário César Carvalho
Published: May 2017

Introdução: As doenças cardiovasculares estão em primeiro lugar entre as causas de morte no Brasil. A doença cardíaca hipertensiva (DCH) descreve um espectro de resposta de órgãos-alvo, que inclui doença arterial coronariana, hipertrofia ventricular esquerda, insuficiência cardíaca e arritmias.Objetivo: Realizar uma análise epidemiológica da mortalidade por DCH nas macrorregiões brasileiras.Materiais e Métodos: Estudo descritivo das taxas de mortalidade de base populacional com dados secundários e uma análise comparativa entre as macrorregiões brasileiras, utilizando as variáveis: sexo, faixa-etária, ano do óbito, cor/raça e escolaridade.Resultados: Observou-se grande acréscimo nos coeficientes de mortalidade brutos a partir de 40 a 59 anos. A DCH acometeu principalmente pessoas pardas nas regiões norte, nordeste e centro-oeste e indivíduos brancos nas regiões sul e sudeste, provavelmente por maior predomínio desses fenótipos nas respectivas áreas. Quanto ao sexo, a mortalidade é elevada em ambos. O número de óbitos é inversamente proporcional à quantidade de anos de escolaridade em todas as regiões, sendo os maiores valores no grupo de analfabetos.Conclusão: Observamos que com o aumento da idade há elevação do coeficiente de mortalidade, especialmente onde há maior precariedade na assistência à saúde, nas medidas de prevenção, controle e acompanhamento, além de repasse de recursos, a exemplo da região nordeste.
Pressão do cuff em pacientes em ventilação mecânica – relação com a mudança de decúbito
Authors: Ferreira Elenice Gomes , Rickli Poliana , Molina Filho Ênio Teixeira , Fischer Jefferson , Antunes Mateus Dias , Do Nascimento Júnior Jose Roberto Andrade , De Oliveira Daniel Vicentini
Published: May 2017

Objetivo: Verificar a pressão intra-cuff de pacientes sob ventilação mecânica e a relação com a mudança de decúbito.Materiais e Métodos: Trata-se de um estudo transversal. Para a verificação da pressão intra-cuff foi adaptado um cufômetro através de um manômetro, tendo como referência a pressão de 20 mmHg. No primeiro dia, inicialmente foi mensurada a pressão intra-cuff com o paciente em decúbito dorsal com cabeceira a 30º, seguido do decúbito lateral de costa para o ventilador e na sequencia o decúbito lateral de frente ao ventilador. Do segundo ao quinto dia foi verificada a pressão somente em decúbito dorsal com cabeceira a 30º. Para a análise dos dados foram utilizados os testes de Kolmogorov-smirnov e os testes t de Student independente e dependente (p<0,05).Resultados: Nos cinco dias consecutivos de verificação da pressão intra-cuff na posição de decúbito dorsal observou-se que estas estavam levemente diminuídas comparadas ao valor de referência, onde o terceiro dia foi verificado a menor pressão (16,4±15,1). Ao realizar a mudança de decúbito notou-se que as pressões intra-cuff apresentaram variações acima ou abaixo de 20 mmHg, que ao analisar a diferença entre as médias das pressões foram estatisticamente significativas (p=0,001) e (p=0,014). O decúbito lateral de costa para o ventilador apresentou-se com valores pressóricos dentro do referencial (20,3±6,5), enquanto houve diminuição no decúbito de frente para o ventilador (18,1±4,8).Conclusão: Conclui-se que as médias das pressões intra-cuff em cinco dias consecutivos apresentaram-se diminuídas. Apenas no quinto dia as pressões mantiveram-se em valores considerados normais e a mudança de decúbito influenciou significativamente na alteração desta pressão.
Validation and application of HPLC–ESI–MS/MS method for the determination of irsogladine
Authors: Hoang N. H. , Huong N. L. , Hong S.-Y. , Park Je Won
Published: May 2017

A highly sensitive analytical tool for the fast quantification of irsogladine in human plasma was developed. Cleanup using a solid-phase extraction technique is a simple method for extracting both irsogladine and lamotrigine (internal standard) spiked into human plasma. The resolvable separation of both analytes through reversed-phase high-performance liquid chromatography (HPLC) was carried out within 5 min. The HPLC–electrospray ionization (ESI)–tandem mass spectrometry (MS/MS) method, which was operated in a selected reaction monitoring mode specific to the target analytes, was verified for use in the quantification of irsogladine. The inter- and intra-day precision (relative standard deviation, RSD) of irsogladine spiked into quality control samples were <7%, and their accuracies were between 96.6% and 102.1%. The calibration curve for irsogladine spiked into human plasma was linear over the range from 1.8 to 100 ng mL−1 with lower limit of quantification at 1.8 ng mL−1. The established method was successfully applied for a bioequivalence study of irsogladine.
Isolation and purification of two tyrosinase inhibitors from camellia pollen by high-speed counter-current chromatography
Authors: Yang Y.-F. , Lai X.-Y. , Huang G.-L. , Chen Y.-H. , Du X.-P. , Jiang Z.-D. , Chen F. , Ni H.
Published: May 2017

Bee pollen is a health food with a wide range of nutritional and therapeutic properties. However, the bioactive compounds of bee pollen have not been extensively revealed due to low efficacy in separation. High-speed counter-current chromatography (HSCCC) and solvent extraction were applied to separate tyrosinase inhibitors from camellia pollen in this study. The camellia pollen extracts prepared with petroleum ether, ethyl acetate, and n-BuOH have tyrosinase inhibitory activity. Acidic hydrolysis could promote the tyrosinase inhibitory activity of crude sample. Three fractions with tyrosinase inhibitory activity were separated from the hydrolysate by a one-step HSCCC procedure. Among the fractions, two chemicals were sufficiently purified and identified to be levulinic acid (LA) and 5-hydroxymethylfurfural (5-HMF). The recovery was 0.80 g kg−1 pollen for LA and 1.75 g kg−1 pollen for 5-HMF; and their purity was all over 98%. The study demonstrates that HSCCC method is powerful for preparative separation of tyrosinase inhibitors from camellia pollen.
The Effect of Film Composition on the Texture and Grain Size of CuInS2 Prepared by Chemical Spray Pyrolysis
Authors: Jin Michael H.-C. , Banger Kulbinder K. , Harris Jerry D. , Hepp Aloysius F.
Published: May 2017

Ternary single-source precursors were used to deposit CuInS2 thin films using chemical spray pyrolysis. We investigated the effect of the film composition on texture, secondary phase formation, and grain size. Films with either (112)- or (204/220)-preferred orientation were deposited with most often In-rich composition. The (112)-preferred orientation became more pronounced as the film composition became more In-poor. Films with a (204/220)-preferred orientation were both In-rich and contained a yet unidentified secondary phase. The phase was evaluated as an In-rich compound based on composition analysis and Raman spectroscopy. Further experiments showed that the phase could be removed by depositing a thin Cu layer prior to the growth of CuInS2. Similarly, as-grown Cu-rich (112)-oriented films did not exhibit the In-rich compound. The (204/220) preferred orientation of the film is likely related to the equivalent symmetry between planes of CuInS2 and the In-rich compound. The largest grain size (∼ 0.5μm) was achieved with Cu-rich (112)-oriented films.
Neue Arzneimittel für Pferde und landwirtschaftliche Nutztiere 2016
Authors: Emmerich Ilka Ute
Published: May 2017

Im Jahr 2016 kam für Pferde und landwirtschaftliche Nutztiere nur ein neuer Wirkstoff auf den deutschen Tierarzneimittelmarkt. Der Immunmodulator Pegbovigrastim steht jetzt als Injektionslösung für Rinder zur Verfügung (Imrestor®). Vier Wirkstoffe erhielten eine Tierartenerweiterung. So wurde das Ektoparasitikum Amitraz (Apitraz®) aus der Gruppe der Triazapentadiene auch für Honigbienen, das Expektorans Bromhexin (Exflow® Vet) auch für Hühner, Puten und Enten und das Makrolidantibiotikum Gamithromycin (Zactran®) auch für Schweine zugelassen. Des Weiteren erhielt der Dopamin-D2-Rezeptoragonist Cabergolin (Velactis®) eine Zulassung für Milchrinder, für die allerdings wenige Monate nach Markteinführung wegen schwerwiegender Nebenwirkungen das Ruhen der Zulassung angeordnet wurde. Außer dem kamen ein Präparat mit einer neuen Wirkstoffkombination und ein Wirkstoff in Monozubereitung für Pferde und landwirtschaftliche Nutztiere auf den Markt.
Development and Analysis of Quality Parameters of an Innovative Juice
Authors: FARCAS Anca , MURESAN Crina , TOFANA Maria , MIRCA Simona
Published: May 2017

Nowadays, the functional products represent a sustainable trend in food industry due to the beneficial effects that they have on the human body as well as due to the increased interest of people for a healthy and balanced lifestyle. The aim of the present study was to develop and optimize a pumpkin and apple functional juice, respectively to accomplish the quality control in terms of its physicochemical and sensorial properties. The highest levels of vitamin C occurred in pumpkin and implicitly in the juice obtained in the 1:1 ratio, which also presented the highest antioxidant activity. The nitrates content was at very low level in all the analysed sample, with values between 24.7-41.2 mg/kg for apple and pumpkin, respectively between 28.41-30.94 mg/kg for juices. Also, the consumers were impressed by sensorial and nutritional properties of the new product, positively appreciating both variants of juice.
Towards the development of eco-industrial estates in Bhutan
Authors: Wangdi Sonam Chuki , Nepal Madhav Prasad
Published: May 2017

This paper investigates the potential of applying industrial ecology in the development of eco-industrial estates in Bhutan. It presents the factors contributing to the success or failure of eco-industrial estates along with the benefits arising from the set-up of such facilities to industry, the environment and local communities. The development strategies, policies, practices, laws, rules and regulations, market conditions and private-sector initiatives undertaken in Kalundborg Eco-industrial Park, Burnside Eco-industrial Park and Map Ta Phut Industrial Estate in Denmark, Canada and Thailand, respectively, are used to analyse eco-industrial development in Bhutan. The existence of supportive legislation, a close working relationship between the government and private sector, enabling an environment for information sharing, and a diverse mix of industries in Bhutan are identified as the key opportunities and supportive conditions for as well as the challenges to eco-industrial development in Bhutan and realisation of the government’s vision for a ‘cleaner’ industrial sector.
Cracking in walls with combined base and end restraint
Authors: Micallef Marianna , Vollum Robert L. , Izzuddin Bassam A.
Published: May 2017

Restraint of early-age thermal and long-term shrinkage strain can cause cracking in reinforced-concrete members. Eurocode 2 provides guidance on the design of crack control reinforcement in reinforced-concrete elements with base (edge) and end restraint, but not combined base and end restraint, which commonly occurs. The paper describes an experimental programme, which was conducted to investigate early-age and long-term shrinkage cracking in reinforced-concrete walls with combined base and end restraint. The main variables in the test programme were concrete cover and reinforcement ratio. Early-age cracking is simulated with non-linear finite-element analysis, which is shown to capture the observed behaviour adequately. Eurocode 2 gives reasonable estimates of long-term crack widths in the tested walls if edge restraint is assumed, but significantly overestimates crack widths if the worst case of end restraint is assumed.
Using carbon-fibre-reinforced polymer to strengthen concrete-filled steel tubular columns
Authors: Vijay Shankar G. R. , Sundarraja M. C. , Kim Yun Yong , Ganesh Prabhu G.
Published: May 2017

External bonding of carbon-fibre-reinforced polymer composites has been proposed as an innovative technique to strengthen steel structures. This paper discusses an experimental study carried out to investigate the feasibility of using carbon-fibre-reinforced polymer composite strips for strengthening concrete-filled steel tubular columns. In this study, columns were strengthened using polymer composite strips 50 mm wide at two different spacings. They were then tested under compression until failure. The test results are discussed in terms of failure modes, stress–strain behaviour, load-carrying capacity and ductility. The results show that externally bonding composite polymer strips is an effective approach to restraining axial deformation and enhancing the ultimate capacity of columns under compression. By bonding the strips, the deformation of the columns was restricted to a maximum of 141·2% and 69·75% compared to the reference column when set at spacings of 20 mm and 40 mm, respectively. The capacity of the columns increased by about 30% for a 20 mm spacing, whereas no significant increase in capacity was observed for a 40 mm spacing. It is therefore recommended to apply this technique for strengthening and rehabilitating concrete-filled steel tubular columns and to use a 20 mm spacing.
Testing specimen effect on shrinkage of lightweight concrete
Authors: Vakhshouri Behnam
Published: May 2017

The shape and size of the testing specimen influence the measured shrinkage strain of concrete at different ages. This study compares the shrinkage strain of lightweight concrete containing treated expanded polystyrene beads measured by prism (285 × 75 × 75 mm) and cylindrical (150 × 300 mm) specimens for 225 d after 7 and 14 d of moist-curing, respectively. The shape of the specimen had a distinct effect on the shrinkage, especially immediately before and after the age of 60 d. The increasing trend of the shrinkage strain in the prism and cylinder specimens was different. Considering the specimen shape, a relationship is proposed and verified by the existing models and experimental data to predict the shrinkage strain of lightweight concrete.
Intensive online foreign language learning at the advanced level
Authors: Enkin Elizabeth
Published: May 2017

Hybrid and online foreign language courses are becoming increasingly more important for students. However, several gaps in the literature point to needing studies investigating courses taught online, at the advanced level, and during intensive summer timeframes, since these classes can be advantageous for learners. This paper discusses an advanced-level online Spanish grammar course that was taught during the summer, and examines: (1) learning gains from a beginning-ofcourse test to end-of-course test (i.e., a pretest-posttest covering course content), and (2) students’ perceptions of the course gleaned from an end-of-course survey, which collected both quantitative and qualitative data. The pretest-posttest results showed a significant improvement in learners’ scores, and the survey results indicated mixed opinions. Specifically, positive course attributes included the course’s self-paced nature and practical benefits, however the course’s fast-paced nature may have led to several drawbacks. These findings offer insight into these types of courses, and may prove helpful for instructors who want to plan similar classes.
O que faz você feliz? Reflexões sobre a psicologia na sociedade de consumo
Authors: Acselrad Marcio , Lopes Josefa Crysleide Rodrigues
Published: May 2017

O presente trabalho objetiva identificar como se dá a busca pela felicidade através do consumo e quais são as implicações subjetivas desse processo através da investigação de como a psicologia define o que é a felicidade e como esta se relaciona com as atuais práticas de consumo. Para tanto foi feita uma revisão bibliográfica sobre o tema juntamente com a realização de entrevistas com psicólogos e um grupo focal com estudantes universitários. A partir das informações obtidas pode-se fazer uma explanação sobre a definição de felicidade e como o consumo é a ela atrelado. Assim, pudemos compreender que a felicidade é fruto de muitas fontes e vivências e que o consumo tem sido um meio privilegiado de se conseguir prazer e bem-estar.
O fenômeno da autocracia dentro do processo grupal
Authors: Blauth Angela Cruz
Published: May 2017

RESUMO

Buscando levantar uma reflexão acerca da autocracia operando em sistemas grupais, foi realizada uma revisão teórica a fim de esclarecer o tema, integrada juntamente à analise do filme A Onda. A experiência autocrata retratada no filme entre professor e alunos, mostra-se compatível às teorias grupais psicanalíticas, que buscam explicar como certos tipos de grupo se formam, qual a característica de seus líderes, e quais as motivações inconscientes que delineiam o funcionamento deste grupo. O presente trabalho revisitou o governo Hitler, sendo este um dos principais modelos de autocracia totalitária da história, além de ter sido tomado como base para a constituição de grupo no filme. A teoria social-histórica e a psicanálise se integram neste trabalho em uma mesma perspectiva.

Palavras Chave: Grupos, psicanálise, A Onda, Hitler, autocracia, totalitarismo.

ABSTRACT

Seeking to raise a debate about autocracy in group operating systems, a literature review was performed to clarify the issue, along with integrated analysis of the film The Wave. The autocrat experience portrayed in the film between teacher and students seems compatible to psychoanalytic group theories that seek to explain how certain types of groups are formed, leader’s characteristic, and which unconscious motivations operated in this kind of group. This article revisited the Hitler government, for being one of the main models of totalitarian autocracy of history, and has been taken as the basis for the formation of the group in the film. The social-historical theory and psychoanalysis integrate this work in the same perspective.

Keywords: Groups, psychoanalysis, The Wave, Hitler, autocracy, totalitarism.