bluuebunny/crossref_metadata_2025 huggingface dataset:
Coffin-Siris syndrome - one syndrome with various genetic variants and phenotypes
Authors: Boyarchuk O.R. ,   I. Horbachevsky Ternopil National Medical University, Ukraine, Chubata O.B. , Smashna O.Ye. , Makukh H.V. ,   Ternopil Regional Children's Clinical Hospital, Ukraine,   I. Horbachevsky Ternopil National Medical University, Ukraine,   LeoGEN Scientific Medical Genetic Center, Lviv, Ukraine,   Regional Center of Neonatal Screening, Municipal Non-Profit Enterprise Lviv Regional Clinical Perinatal Center, Ukraine
Published: July 2024

Coffin-Siris syndrome encompasses a group of genetic disorders with a wide spectrum of phenotypic features, characterized by varying degrees of intellectual disability, developmental delay, and other clinical signs. Among the most common features are the aplasia or hypoplasia of the distal phalanx or nail of the fifth finger and coarse facial features. The aim of the work is to increase awareness among physicians about the diagnosis of Coffin-Siris syndrome and expand knowledge of the spectrum of clinical features of the disease based on the presentation of two clinical cases. We presented two clinical cases of Coffin-Siris syndrome caused by variants in the SMARCA4 and DPF2 genes. In both cases, there is a delay in speech development, cognitive impairments of varying severity, behavioral changes, characteristic dysmorphic features, and changes in the hands and/or feet, especially in the little finger. Distal phalanx nail hypoplasia of the fifth finger was present in the case associated with a variant in the DPF2 gene. In the patient with a variant in the SMARCA4 gene, flexion deformity of the little finger and broad palms were observed. Pachydermodactyly and a congenital kidney defect were also diagnosed in this patient. Thus, genetic diagnosis allows for timely identification, preventing complications and avoiding unnecessary investigations. Accumulating clinical data on rare diseases and their systematization contribute to research development and, subsequently, to determining optimal therapeutic approaches. The identified genetic factor in the proband ensures genetic counseling for the family and determining risk indicators for pathologies in offspring. The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
Single-nucleotide variant rs1800139 of the LRP1 gene as a factor in the development of obesity in children
Authors: Abaturov O.Ye. ,   Dnipro State Medical University, Ukraine, Nikulina A.O. ,   Dnipro State Medical University, Ukraine
Published: July 2024

In the development of postnatal obesity and associated metabolic disorders, genetic features occupy a prominent place among various obesogenic factors. One of the genes that controls adipogenesis and determines the development of adipose tissue is the human low-density lipoprotein receptor-related protein 1 (LRP1) gene. The aim: study of the frequency of SNVs of the LRP1 gene in children with different phenotypes of obesity. Materials and methods. 253 obese children aged 6-18 years were examined. The main group (n=153) was made up of children with metabolically unhealthy obesity (MUO) according to IDEFICS 2014 criteria. The control group (n=100) was made up of children with metabolically healthy obesity (MHO). All children underwent a general clinical, immunobiochemical examination (Synevo, Ukraine). Whole-genome sequencing (CeGat, Germany) was performed in 31 children of the primary and 21 children of the control group. Static analysis: variational analysis, Wald analysis, calculation of χ2, Kramer's independence test, Spearman's correlation analysis, ROC analysis. Results. As a result of testing statistical hypotheses based on the conjugation table of features from 743 SNVs of 86 candidate genes studied, the greatest association with MUO was found in SNV rs1800139 LRP1 (V=0.44). In patients with MHO, the CC genotype was significantly less common (p<0.05) and the TT genotype of SNV rs1800139 of the LRP1 gene was more often registered than in the general human population (p<0.02). In patients with MUO, both homozygous genotypes of SNV rs1800139 of the LRP1 gene occurred significantly less frequently than in the general human population (p<0.05). Among patients with MUO, the TT genotype of SNV rs1800139 of the LRP1 gene occurred significantly less often compared to the group of patients with MHO (p<0.01). Conclusions. The СT genotype SNV rs1800139 of the LRP1 gene is highly associated with the presence of MUO and the development of dyslipidemia in children. The research was carried out in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of the institution mentioned in the work. Informed consent of parents or their guardians was obtained for conducting research. The authors declare no conflict of interest.
Significance of surfactant proteins in respiratory distress syndrome in preterm infants
Authors: Mirzayeva İ.A. ,   Azerbaijan Medical University, Baku, Baylarov R.O. , Gasimova Y.A. , Orujova P.A. ,   Azerbaijan Medical University, Baku,   Azerbaijan Medical University, Baku,   Azerbaijan Medical University, Baku
Published: July 2024

Respiratory diseases are considered to be widespread pathologies among preterm infants. The research aim was to determine the level of surfactant protein A (SP-A) in the blood and tracheobronchial lavage of infants with respiratory distress syndrome (RDS) and pneumonia, as well as to study its significance in predicting pathological processes in the lungs. Materials and methods. The study involved 80 very low birth weight infants with respiratory distress (2a - subgroup RDS, 2b - pneumonia), 42 extremely low birth weight infants (3a - RDS and 3b - pneumonia subgroups), and 20 children without respiratory distress (control group - 1). Results. The initial examination showed that the level of SP-A in venous blood in the control group was 2.9±2.3 ng/ml, while in the 2b group, it was 21.2 ng/ml, which was 7.1 times higher compared to the control group. In group 2, the difference between 2b (21.2 ng/ml) and 2a (6.01 ng/ml) was determined to be 3.5 times. A direct correlation was observed between the level of SP-A in the blood and the oxygen dependence of patients with RDS (r=0.240, p<0.05). In addition, an increase in the level of the inflammatory marker C-reactive protein (CRP) was observed in these patients over time, and a correlation was found between the level of SP-A in the blood and CRP. When comparing the level of SP-A between deceased and surviving infants, it was found to be that SP-A 2.9 times higher in the blood of deceased patients compared to surviving infants, and conversely, 2.3 times higher in tracheobronchial lavage in surviving infants compared to the deceased patients. Based on the results obtained, the importance of SP-A in the differential diagnosis and prognosis of RDS is emphasized. The research was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution indicated in the work. The informed consent of the children's parents was obtained for conducting the studies. No conflict of interests was declared by the authors.
On the Convergence of Swap Dynamics to Pareto-Optimal Matchings
Authors: Brandt Felix , Wilczynski Anaëlle
Published: July 2024

We study whether Pareto-optimal stable matchings can be reached via pairwise swaps in one-to-one matching markets with initial assignments. We consider housing markets, marriage markets, and roommate markets as well as three different notions of swap rationality. Our main results are as follows. While it can be efficiently determined whether a Pareto-optimal stable matching can be reached when defining swaps via blocking pairs, checking whether this is the case for all such sequences is computationally intractable. When defining swaps such that all involved agents need to be better off, even deciding whether a Pareto-optimal stable matching can be reached via some sequence is intractable. This confirms and extends a conjecture made by Damamme, Beynier, Chevaleyre, and Maudet (2015) who have shown that convergence to a Pareto-optimal matching is guaranteed in housing markets with single-peaked preferences. We prove that in marriage and roommate markets, single-peakedness is not sufficient for this to hold, but the stronger restriction of one-dimensional Euclidean preferences is.
Evidence of contingency factors related to financial management in state secretariats in the northern region of Brazil
Authors: Lopes Júnior Pedro de Lima , Pereira Deivison Gustavo Costa , Sell Filipy Furtado , Zonatto Vinícius Costa da Silva
Published: July 2024

This research aims to highlight the contingency factors influencing financial management in governmental entities. To achieve this goal, a descriptive, qualitative methodology was adopted, with data collection via individual electronic surveys sent to employees of different secretariats within a Brazilian state. The theoretical framework identified the following contingency variables: Environment, Structure, Technology, Information Technology, and Strategy. The results indicate that Contingency Theory (integration of contingency factors) impacts financial management, with Strategy being the only contingency variable showing interference in financial management when analyzed separately. Thus, the analyzed secretariats align with regulations, addressing managerial issues related to Environment, Structure, Technology, and Information Technology factors.
Producción de beauveria bassiana para la formulación de bioplaguicidas
Authors: Lucero Jessenia , Manzano Jorge , Loaiza Iliana , Orellana Yamile
Published: July 2024

The harmful effects of chemicals in conventional agriculture and the growing demand for food free of toxic residues has developed environmentally sustainable strategies. An effective alternative for integrated pest management in agricultural crops are biopesticides formulated with microorganic structures or from the production of active compounds. This paper describes the production processes of Beauveria bassiana for formulating biopesticides for agricultural use. The information was collected through a systematic search in Research Gate, Google Scholar, Science Direct and PubMed, using keywords such as production, Beauveria bassiana, solid fermentation, liquid fermentation and metabolites. The results affirm that B. bassiana is one of the microorganisms with great potential to produce biopesticides, due to the entomopathogenic mechanism of action and secondary metabolites, which can be used for the biological control of phytophagous insects. Likewise, for the formulation of B. bassiana it should be considered a profitable culture medium for large-scale production, also the control of environmental variables such as temperature at 25 oC, relative humidity 65-70 %, pH of 5.4, propagation time between 4 to 8 days, and for the liquid fermentation process, a constant agitation between 200 to 400 rpm must be maintained. Biological products represent an alternative to minimize the use of synthetic pesticides, reduce environmental pollution and ensure food safety and security.
Evaluación de la composición química del extracto alcohólico de Gynoxys cuicochensis cuatrec: identificación de metabolitos y exploración de sus propiedades farmacológicas
Authors: Montaño Cabrera Angel , Cartuche Angel , Gilardoni Gianluca , Espinosa Tapia Sandra , Malagón Avilés Omar , Cumbicus Torres Nixon
Published: July 2024

Gynoxys cuicochensis Cuatrec., a member of the Asteraceae family, inhabits the Fierro Urco moor in the province of Loja. Despite not being used in traditional medicine, it possesses significant landscape value due to its striking yellow inflorescence. For investigating its chemical composition and potential pharmacological properties, a phytochemical characterization of the plant’s ethanolic extract was conducted. The extract was obtained through static maceration for three days for the initial filtration, followed by one day for the second and third filtrations. Chlorophyll was se- parated using Diaion HP-20 resin as a solid phase packed in separation funnels, and an ethanol:water liquid phase with a concentration gradient ranging from 6:4 to 9:1 for elution. The dechlorophyllized extract was then freeze- dried and fractionated using gravity column chromatography. The obtained fractions were further purified through microcolumn and preparative chromatography. To elucidate the chemical structure of the molecules, nuclear magnetic resonance spectroscopy and electrospray ionization mass spectrometry were employed. Two metabolites were isolated for this study. The first one is a known glycosylated flavonoid called Nicotiflorin, while the second one is a phenolic derivative named 1,3-di-O-trans-feruloylquinic acid, which lacks a precise pharmacological description. This discovery represents an interesting and unique finding for this species, suggesting its potential medicinal use.
Rigor y objetividad como fundamentos de la racionalidad de la física en Evandro Agazzi
Authors: Rivera Guerrero Linda Marcela , Castellanos Muñoz Arjuna Gabriel , Gómez Rodas Carlos Andrés
Published: July 2024

In current epistemology, there are two opposing attitudes towards the empirical sciences. Onthe one hand, they appear as an essential tool for the advancement of knowledge. On the otherhand, there is doubt about the metaphysical and epistemological bases of this confidence inscientific knowledge, which has led science down paths of skepticism and pragmatism. This paper aims to contribute philosophically to the rationality and ontological status of physics, taking as a starting point some works of the philosopher of science Evandro Agazzi. The article presented hereintroduces Agazzi’s thought and the core issues of his epistemology. It then defines the concepts of rigor and objectivity as understood by Agazzi, and finally establishes criteria of rigor and objectivity for physics, showing how they are verified in two classical experiments. Based on these ideas, it is shown that physics, as the science it is, has criteria of rigor and objectivity that allow it to effectively reach the real, thus responding to the formalist and pragmatist challenge. Thus, the article does notexhaust itself in a description of Agazzi’s thought, but will apply his ideas to the concrete field of physics, making explicit ideas that have not been sufficiently made explicit by the Italian philosopher.
Realismo, Relatividad General y el Gato de Schrödinger
Authors: Restrepo Echavarria Ricardo
Published: July 2024

The present work examines the nature of reality, including the possibility of freedom, in the framework of modern physics. Additionally, it proposes a reform for the metaphysics of realism.For realism, the world is the way it is independent of the mind. However, general relativity supposesthat the speed of objects and the temporal order of events depend on the frame of referenceadopted. Which frame of reference is adopted depends on human interests. However, there are still physical facts independent of the frame of reference: the speed of light, spacetime distance,and the equivalence of matter and energy, amongst others. On the other hand, the CopenhagenInterpretation supposes that quantum states are in a superposition that is only realized at themoment of observation, leading to the implication that Schrödinger’s cat is both alive and deaduntil observed. However, less incredible realist possibilities are analysed. Modern physics, whetherdeterminist or indeterminist, also threatens the possibility of freedom. The compatibility of freedom as self-government and modern physics is analysed and developed. Although central aspectsof realist metaphysics are conserved, a philosophical-scientific conception of the universe that integrates mental beings within it emerges, which supposes a reform for standard scientific realism. The existence of facts independent of what we happen to think is saved alongside ineliminable mental phenomena.
Analogía entre diferencia de potencial eléctrico y diferencia de potencial gravitacional en la enseñanza de la física
Authors: Lima Bahia Raira Maria , Gómez Jaime Pedro Javier
Published: July 2024

The current research proposes to create a strategy that enables solid learning of the topicof electrical potential, through an analogy between electrical and gravitational potentials. The proposed activity conceives the use of low-cost materials with the objective of bringing physical knowledge closer to the students’ daily lives. This is because a certain lack of interest in Physics has been perceived in the focus population of this study, which in some way is contradictory, since thepresence of this science in our daily lives is manifested in the various activities that we carry out.in the context in which we are inserted. As well as, in the widespread use of new information andcommunication technologies to which the human species has been having access in recent years. For its part, for the creation of the aforementioned strategy, the use. The methodology includes a review of the available literature on the subject and has a qualitative-quantitative tendency, referring to the collected data’s analysis during the experience. The results shows that there were better students performances during the second stage of the research process. Which allows us to conclude that teaching Physics through analogies developed by the teachers of this subject enables better learning of this science to the extent that scientific and everyday knowledge are linked.
The problem of the knowledge of the thinking substance in the Meditations and in the Objections and Replies of Rene Descartes
Authors: França Freitas Vinícius , Teodoro Sousa Ana Cláudia
Published: July 2024

In this article, the hypothesis is developed that Descartes does not clearly articulate theknowledge of the thinking substance in the Meditations on First Philosophy and in Objections and Replies. It is argued that such exposition is necessary for a comprehensive understanding of the status of Cartesian philosophy at the time of writing the Meditations, particularly to grasp Descartes' conception of the knowledge of the thinking substance in the years 1641 and 1642. Asknown, knowledge of the thinking substance is a fundamental element in Descartes' philosophy.Firstly, Descartes' two modes of presenting knowledge of the thinking substance in the Meditations are examined, highlighting the issues each entails. Secondly, drawing from the Objections andReplies: especially the fifth and seventh, criticisms from Pierre Gassendi and Pierre Bourdin regarding the knowledge of the thinking substance are presented. Both Gassendi and Bourdin emphasize that the text of the Meditations does not sufficiently clarify how the thinking substanceis known. They question the possibility of such knowledge, pointing out the ambiguity andobscurity of Cartesian responses. It is concluded that in the Meditations, Descartes confronts aninsurmountable gap between the ontology of substance and its knowledge, which prompts him tofurther develop and clarify his theory in later writings.
Fundamentos filosóficos para una pedagogía de la cultura
Authors: Esparza Urzúa Gustavo Adolfo
Published: July 2024

The general objective of this paper is to elaborate a pedagogical reading of Ernst Cassirer’sPhilosophy of Symbolic Forms, focusing on the Phenomenology of Knowledge where the author detailsthat the foundations adduced by Paul Natorp, in Introduction to Psychology constitute a critical viewof psychology as the foundation of intellectual operations. In general, there are three results to beshown: first, it will be shown that this recovery of the Natorpian vision allows Cassirer to maintainthat all cultural activity (language, mythology, art, science, etc.) has as its foundation the psychologicalactivities of the subject, which implies that all symbolic formation is both an intellectual product ofthe individual and a cultural activity. Second, it will be shown that part of the development of acritical psychology, in accordance with Natorp’s general plan, is the need for a theory of formationthat explains how the cultural environment shapes the intellectual activities of the subject, a generalthesis assumed by Cassirer for the development of his theory of the symbol. Finally, it will be notedthat the cultural formative agents considered by Natorp for the formation of the individual (state,art and religion, mainly) constitute the theoretical bases of culture on which the student will laterdevelop his theory of language, myth/religion, art and science as cultural formations.
Do Not Extract Teeth which you could Restore Perhaps you do?
Authors: Peter F Kurer
Published: July 2024

The Kurer Anchor System, a once widely used dental restoration method, offered a solution for retaining root canal posts in treated teeth. Despite its success in preserving natural teeth and providing a cost-effective alternative to implants, the system's popularity waned due to changes in the dental industry. This paper revisits the Kurer Anchor System, examining its clinical efficacy, economic advantages, and potential integration with modern dental practices. Emphasizing the importance of implant surface cleanliness, the paper advocates for the revival of the Kurer Anchor System in contemporary dentistry. The conclusion underscores the need for educating dental professionals about this system's benefits and proper application.
DEVELOPMENT OF POP UP BOOK LEARNING MEDIA AT THE FIVE GRADE IPA CONTENT OF WONOKERTO STATE ELEMENTARY SCHOOL
Authors: Lanti Mei , Harmoko Haromoko , Egok Asep Sugenda
Published: July 2024

This research aims to develop teaching media products in the form of pop up book learning media. On the content of science class V SD Negeri Wonokerto which is valid, practical and effective for use in the learning process. The research method is RD (Research and development), with the ADDIE development model used analysis, design, development, implementation and evaluation. Based on the results of the analysis of assessments obtained from language validation experts, the average score of 0.87 is included in the high category, material experts have an average score of 0.84 in the high category and media experts have an average score of 0.77 including the fairly high category. Then the results of the practical analysis of students obtained an average of 92% for small groups very practical criteria, and large groups scored 97% very practical criteria and teacher practicality scored 94% very practical criteria. The quality of the pop up book media seen from the practical aspect is categorized as very practical with an overall score of 94% being very practical. Then the results of the effectiveness analysis obtained an average pretest score of 21.2 and a posttest score of 73.8 and the classical learning completeness criteria obtained a score of 66.7% including the "Good" category.
Application of moderation in determining natural disaster mitigation strategies as inclusive education in elementary school
Authors: Kosim Kosim , Stahrizal Syahrizal , Gunada I Wayan
Published: July 2024

Natural disaster mitigation learning is inclusive education in elementary school. There for, this aims to express the responses and opinions of teachers about the implementation of the disaster mitigation learning model and to improve the ability of teachers in elementary schools. The study was conducted on three schools consist elementary schools in Mataram, Ampenan, and Sembalun in Lombok Island-West Nusa Tenggara-Indonesia. The method of research begins with a presentation of a learning model for natural disaster mitigation such as peer teaching by the research team. After that discussion with moderation technique regarding disaster mitigation learning structure applied in the previous presentation. The results of the study obtained 5 main ideas of strategies about the implementation of the natural disaster mitigation learning model, namely that 1) students must be conditioned to natural disasters in the learning process, 2) teachers must have the correct steps in providing the understanding of natural disasters and in conducting direct demonstrations so that students thoroughly understand, 3) teachers must have knowledge of earthquakes, tsunamis, landslides, floods, hurricanes and volcanoes, 4) teachers provide examples of disaster mitigation learning to students using tools such as videos, disaster mitigation tools, etc, 5) understanding risk, vulnerability, threat and capability of natural disaster. In general conclusion, teachers have to ability to use technology pedagogical and content knowledge strategies for natural disaster mitigation learning.
Implications of the principle of involvement in learning design at elementary school level
Authors: Sibarani Debora Pratiwi , Nurdin Rachmy Aryati
Published: July 2024

A learning process requires the direct involvement of students to develop their potential to prepare them to seek opportunities and manage the challenges of the coming smart society 5.0. However, the involvement of students does not guarantee active learning in the classroom. This article will define the principle of involvement in learning, describe two learning approaches that can engage students in learning physically, mentally, emotionally, and intellectually, and explain the implications of these learning approaches in concrete learning for educators and students. This article used a literature review as a qualitative method to describe the principle of involvement through two learning approaches, namely John Dewey's Learning by Doing Theory and Barrows and Tamblyn's Problem-Based Learning (PBL) Method. Hence, the readers can see how important the principle of involvement in learning is and its implications as the teacher's ability to serve not only as a facilitator, but also as an activity manager who is able to direct, guide, and encourage students toward predetermined learning goals. Therefore, the direct involvement of students in the learning process is absolute because those experiences aim to alter and enrich them in acquiring the 21st-century skills needed.
Improving science process skills using the STEM (science, technology, engineering, and mathematics) learning model on environmental preservation business material for fifth grade elementary school students
Authors: Rismawati Ade , Kelana Jajang Bayu , Hadianti Yeni
Published: July 2024

Society must be able to adapt in various ways due to the rapid progress of science and technology in the era of globalization. One of the components is education, which is fundamental for the progress of a country. Science process skills are skills for developing the perspective needed to build natural science. This research was conducted to see whether science process skills improved after applying the STEM learning model to environmental conservation business materials, in class V students at SDN 1 Ciledug located in the city of West Bandung. This research was carried out by designing a pretest-posttest group and using a science process skills test, based on the indicators that had been designed. Data analysis to determine differences in perceptions regarding improving students' science process skills, before and after implementing the STEM learning model. The results of data analysis show that science process abilities have increased on the topic of environmental conservation efforts with the application of the STEM learning model. The resulting score with the average value of science process skills increased from application of 40.51 to 85.11. This improvement in skills can be seen from the N-Gain result value of 0.75 which is in the high classification. Thus, the research results that have been presented suggest that teachers can use the STEM learning model as an alternative in science subjects, especially to improve science process skills.
Développement du modèle d'apprentissage des compétences de réflexion d'ordre supérieur (hots) assisté par google sites pour la compréhension écrite niveau A2
Authors: AZIZAH Sofyani Nur , SUNENDAR Dadang , HARDINI Tri Indri
Published: July 2024

RÉSUMÉ.  Cette étude vise à produire des modèles d'apprentissage et des supports valides basés sur les compétences de réflexion d'ordre supérieur (HOTS) pour l'apprentissage de la compréhension écrite au niveau A2. Il s'agit d'une étude de recherche et développement (RD) portant sur le développement d'un modèle d'apprentissage des compétences de réflexion d'ordre supérieur (HOTS) assisté par des sites Google pour l'apprentissage de la compréhension écrite au niveau A2. La recherche a été menée en utilisant la méthode ADDIE (analyse, conception, développement, mise en œuvre et évaluation). Les données ont été obtenues par des techniques d'entretien, des questionnaires et des fiches de validation d'experts. Les résultats montrent que la phase de mise en œuvre du modèle comprend les phases d'activité suivantes : activation des connaissances, analyse du texte, évaluation des informations et création. Sur la base des validations, ce modèle et les supports d'apprentissage peuvent être utilisés pour l'apprentissage de la compréhension écrite au niveau A2 avec un score de 80% (mention très bien). Mots-clés : Compétences de réflexion d'ordre supérieur, Compréhension écrite niveau A2, Google sites, Modèle d’apprentissage.  ABSTRACT. This study aims to produce valid learning models and materials based on higher-order thinking skills (HOTS) for reading comprehension learning at A2 level. The work is a research and development (RD) study on the development of a Google site-assisted higher-order thinking skills (HOTS) learning model for reading comprehension learning at A2 level. The research was conducted using the ADDIE (analysis, design, development, implementation, and evaluation) method. Data were obtained through interview techniques, questionnaires, and expert validation sheets. The results show that the implementation phase of the model includes the following activity phases: knowledge activation, text analysis, information evaluation and creation. Based on the validations, this model and the learning materials can be used for learning reading comprehension at A2 level with a score of 80% (very good). Keywords : Google sites, Higher order thinking skills, Learning model development, Reading comprehension in french level A2
Discours et prédiscours, dans le contexte de la COVID-19, en Côte d’Ivoire
Authors: SANOGO Amidou
Published: July 2024

RÉSUMÉ :  Dans le contexte de la crise sanitaire mondialement ressentie, certaines stratégies politiques sont portées par les discours adressés aux populations. Dans le contexte de la COVID-19, les messages des instances politiques semblent se déduire les unes des autres par voie hiérarchique. Cette pratique langagière permet de déterminer un  prédiscours dont dérive un  discours. Celui-ci doit préciser les intentions et les idées de ce lieu mémoriel de discours, en identifiant des actions à mener pour endiguer la pandémie. Ainsi, ce discours revêt une visée actionnelle  par un acte de langage constatif. Dès lors, il convient de nous interroger sur le rapport entre le langage et l’action : Comment se manifeste, dans le discours politique, le nouage entre le prédiscours qui donne des orientations et le discours qui entend traduire en acte des intentions ? Quels sont les mécanismes et les opérations linguistiques qui font appel au prédiscours ? L’étude vise à comprendre les relations actionnelles entre prédiscours et discours dans la chaîne de transmission des décisions politiques. Il faut déjà énoncer que certains phénomènes linguistiques traduisent la valeur actionnelle des paroles de décisions. L’étude propose une nouvelle approche de l’analyse textuelle en référence à la théorie des opérations linguistiques d’Antoine Culioli et à la théorie fonctionnelle d’André Martinet.  Mots-clés : prédiscours, inter-discours, discours, action, langage, COVID-19  ABSTRACT :In the context of the worldwide health crisis, certain political strategies are supported by the speeches intended for populations. In the case of COVID-19, the messages of political bodies seem to be hierarchically inferred from each other by hierarchical means. This language practice helps to determine a prediscourse from which a speech derives. The latter must specify the intentions and ideas of this memorial place of speech, by identifying actions to be taken to contain the pandemic. Thus, this discourse takes on an action-oriented aim through a constant speech act. The question therefore relates to the relationship between language and action: How does political discourse manifest in the knotting between the prediscourse which gives orientations and the discourse which translates intentions into action ? What are the linguistic mechanisms and operations that call for prediscourse ? The study aims to understand the action relationships between prediscourse and discourse in the chain of transmission of political decisions. It’s important to state that certain linguistic phenomena translate the action value of the words of decisions. The study proposes a new approach to textual analysis with reference to A. Culioli’s theory of linguistic operations and to A. Martinet’s functional theory.  Keywords: prediction, inter-speech, speech, action, language, COVID-19
Training on Students’ Science Process Skills to Achieve Science Learning Outcomes at SMPN 4 Tarogong Kidul [Pelatihan Keterampilan Proses Sains Peserta Didik untuk Mencapai Capaian Pembelajaran IPA di SMPN 4 Tarogong Kidul]
Authors: Purnamasari Shinta , Abdurrahman Dudung , Rahmaniar Andinisa , Lestari Wiwit Yuli , Latip Abdul , Nurfadilah Vina Anggun , Fauziah Siti Rahayu , Nurma’ripat Ikna , Nurdiana Runi , Burhanudin Muhamad Yusuf Fahmi
Published: July 2024

Capaian pembelajaran mata pelajaran IPA pada Kurikulum Merdeka terdiri atas dua elemen, yaitu pemahaman IPA dan keterampilan proses. Hal tersebut mendorong dilakukannya kegiatan pengabdian kepada masyarakat yang bertujuan untuk memberikan pelatihan kepada guru dan peserta didik dalam mengembangkan keterampilan proses sains. Kegiatan ini mencakup 3 tahapan kegiatan, yakni tahap persiapan, pelaksanaan, dan evaluasi. Pada tahap persiapan dilakukan koordinasi antara tim PkM dan peserta PkM. Pada tahap pelaksanaan, dilakukan pelatihan dengan menerapkan teknik on and off-job training. Pelatihan dengan teknik on and off-job training meliputi pemberian materi dan workshop (off-job training), penerapan di kelas (on-job training), serta refleksi dan evaluasi (off-job training).  Pada tahap evaluasi, dilakukan penyebaran kuesioner kepada guru dan peserta didik. Hasil evaluasi menunjukkan respon positif terhadap kegiatan PkM baik dari guru maupun peserta didik. Guru menunjukkan persentase yang tinggi terkait kepuasan terhadap kegiatan PkM (93,33%), relevansi materi PkM dengan kebutuhan guru (90%), dan kebermanfaatan kegiatan PkM (90%). Persentase yang tinggi juga diberikan oleh peserta didik terhadap kegiatan pembelajaran yang dilakukan dalam kegiatan PkM. The learning outcomes of the science in Kurikulum Merdeka consist of two elements, that is scientific understanding and process skills. This encourages the conduct of community service activities with the aim of providing training to teachers and students in developing science process skills. This activity consists of 3 stages: preparation, implementation, and evaluation. In the preparation stage, coordination between the team and participants are conducted. In the implementation stage, training is conducted using on and off-job training techniques. On and off-job training techniques includes providing materials and workshops (off-job training), implementation in classroom on-job training), as well as reflection and evaluation (off-job training). In the evaluation stage, questionnaires are distributed to teachers and students. The evaluation results show positive responses to the community service activities from both teachers and students.  Teachers show a high percentage of satisfaction with the activities (93,33%), the relevance of material to teacher’s needs (90%), and the benefits of activities (90%). Students also give a high percentage for the learning activities carried out in the community service activities.
Adhesion characteristics between keratin fibers and unsaturated polyester
Authors: Ossa Alexander , Paniagua Marco , Ruiz Gladys
Published: July 2024

This work presents the methods and results employed to find the adhesion characteristics between keratin fibers and unsaturated polyester as matrix material. The fibers were conditioned prior to testing using four different methods in order to establish the effect of these treatments on the adhesion to the matrix by means of i) monofilament pull-out testing, as direct method; and ii) Lamina tensile tests as indirect method to analyze the adhesion in the fracture zone with the help of electron microscopy (SEM).
Sensitivity analysis for the positioning of electrodes in surface electromiography (semg)
Authors: Ramírez Angélica , Garzón Diego Alexander
Published: July 2024

The surface electromyography is widely used in laboratories of movement analysis due to its easy manipulation and its noninvasive character. However, this extended use generates a variation in the protocols and produces difficult to compare results [1]. In the present study, an analysis of sensitivity for the positioning of bipolar electrodes is made on three muscles of the quadriceps: vastus lateralis (VL), vastus medialis (VM) and rectus femoris (RF). The three main factors of the study are: a. the longitudinal position of electrode, b. the orientation of electrode and c. the angle of extension of the knee. Additionally, the response factors are the maxima force and the RMS of the EMG signal. The tests were made for maxima voluntary contraction (MVC) during an isometric force. We conclude that there are differences in the EMG signal when the electrodes are in different position and orientation. The best distance for the electrodes is 22.59 ± 2.84% for the VL, 29.44 ± 1.88% for the VM and 66.28 ± 0.38% for the RF from the apex of the patella. The best orientation of the electrodes is 0° for the VL, 70° for the VM and -20° for the RF.
Fingerprint Recognition Using Local Features
Authors: Aguilar Gualberto , Sánchez Gabriel , Toscano Karina , Nakano Mariko , Pérez Héctor
Published: July 2024

Fingerprint recognition is one of the most popular methods used for identification with greater degree of success. The fingerprint has unique characteristics called minutiae, which are points where a curve track finishes, intersect or branches off. Identification systems using fingerprints biometric patterns are called AFIS (Automatic Fingerprint Identification System). In this work a method for Fingerprint recognition is considered using a combination of Fast Fourier Transform (FFT) and Gabor Filters for image enhancement and later a novel method of recognition using local features.
Typical demand curvs of electric power for the residential, commercial and industrial sector of Medellin, using artificial neural networks and algorithms of interpolation
Authors: Tabares Héctor , Hernández Jesús
Published: July 2024

One of the main problems for modeling the electric power consumption in a certain place is the extraction of the knowledge when it is stored in big volumes of information like for example historical registrations. According with this representation, each fact happened and registered consists of a couple of components (t, P) where t represents the time of sample registration and P the electric power consumed at that time. The daily registration has N cases that each of the well-known stimulus-answer couples represents. The objective of this work is to develop a function that allows finding the vector of entrance variables t to the vector of exit variables P. F is any function, in this case the electric power consumption. Their modeling with Artificial Neural Netwok (ANN) is Multi a Perceptron Layer (PMC). Another form of modeling it is using Interpolation Algorithms(AI).
Two dimensional packing problem using a hybrid constructive algorithm of variable neighborhood search and simulated annealing
Authors: Toro Eliana Mirledy , Garcés Alejandro , Ruiz Hugo
Published: July 2024

In this work, the packing of rectangles is modeled based on divisions of the available area, a binary tree codification is used to arrange the pieces so that the guillotines type cutting is guaranteed. A three stages algorithm with individual strategies inspired by algorithms of variable neighborhood search simulated annealing and constructive techniques are used to obtain the solution of the problem. The results obtained are compared using the objective function and percentage used of available area with fifty test cases of the specialized literature and their respective well-known answer with excellent results.
Study and modeling of KR 6 KUKA robot
Authors: Archila-Diaz John Faber , Suell-Dutra Max
Published: July 2024

This work presents the study and modeling of KUKA KR 6 Robot, of robotics laboratory of Federal University of Rio de Janeiro, show the CAD model, the direct and inverse kinematics models and the dynamical model, the direct kinematical model is based in the use of homogeneous matrix, the inverse kinematics use the quadratic equations model, the dynamical model is based in the use of Euler - Lagrange equations, using homogeneous matrix and having in a count the inertial tensor, which one was found with help of CAD tools, is presented the jacobian of manipulator needed for the kinematical control. The work is the first stage for the control of KUKA KR 6 Robot and proposes the implementation of inverse kinematical model in one DSP of Texas Instruments family, analyzing his performance.
A new reaction rate constant for char combustion- formulation
Authors: Rojas Andrés , Barraza Juan , Barranco Richelieu
Published: July 2024

This paper shows the development and formulation of a new reaction rate constant of combustion for pulverized coal. The chemical reaction rate was considered as a function of coal intrinsic reactivity and fuel mass for a reaction order n. The equation for reaction rate constant was developed by dimensional analysis using the Rayleigh method. This equation is new, dimensionless and shows the dependency of the chemical reactivity on coal parameters such as maceral and mineral composition; char parameters, including specify surface area and apparent density, devolatilization time, temperature, and activation energy. The reaction rate constant model presents dimensional consistency and it is described by three dimensionless numbers having physical or chemical significance.
Evaluation of different sources of carbon and nitrogen in the production of rennet from Mucor miehei
Authors: Sánchez Claudia , Gómez Natalia , Osorio Adriana
Published: July 2024

The kinetics of biomass production and rennet from fungi Mucor miehei using culture media with alternative substrates as a source of carbon and nitrogen was studied in order to improve the enzymatic activity. An initial screening was performed in order to select the feasibility of each by-product and from these results the crossed effects of the best sources of carbon and nitrogen over enzymatic productivity were evaluated through an experimental factorial 22 design. It allowed us to propose an alternative culture media viable for the rennet production at industrial scale. The fermentations were carried out in a laboratory batch reactor, at 37° C, pH between 6.3-6.5 and 250 rpm. The best culture media was established as that which contained whey both as a source of carbon and nitrogen (media 1) and whey as a source of carbon and corn flour as a source of nitrogen (media 2). Maximum Rennet strength achieved (FC) was 1333.704 at 90 h in media 1 and 1069.71 at 85 h in media 2.
Evaluation of hydrodynamic behavior as a tool to optimize anaerobic reactors of attached growth
Authors: Pérez Andrea , Torres Patricia
Published: July 2024

The conditions of the non-ideal flow in reactors affect their performance; the common causes are short circuits, dead zones and internal recirculation by kinetics and/or density stream. In this study, the design of an anaerobic filter at full scale that treats cassava starch wastewater was optimized. It presented halt damming problems and low removal efficiencies. The initial hydrodynamic behavior showed the presence of dual flow (32% plug flow - PF and 37% mixed flow -MF), dead zones (20%) and absence of short circuits; additionally the modelling reactor indicated a high dispersion degree and tendency to a mixed reactor in series of two units. Based on these results, the following two modifications were implemented in the reactor design: false bottom and perforated pipe for biogas evacuation. This allowed to increase the PF fraction (44%), reduce the dead zones fraction (15%), decrease the dispersion index (DI) and increase the tendency of the reactor to MF in series of three units, which improved the real hydraulic retention time (HRT) from 9.6 to 10.2 h (HRT theoric 12 hours) and the theoric removal efficiencies from 73 to 78%.
k-NN based regression strategy used to estimate the fault distance in radial power systems
Authors: Morales-España Germán , Mora-Flórez Juan , Vargas-Torres Hermann
Published: July 2024

A regression strategy based on k nearest neighbors (k-NN) to estimate the fault distance in radial power systems is proposed. This fault location approach uses measurements of the fundamental components of voltage and current measured at the power substation. In addition, the approach is not constrained by the power system modeling and it is easily adaptable to the special characteristics of radial systems. The proposed fault locator is tested in a power distribution system and the obtained mean error is lower than 3%, by considering all fault types, several faulted nodes and fault resistances.
Oscillation Control in a Synchronous Machine using a Neural based PSS
Authors: Pérez-Londoño Sandra Milena , Mora-Flórez Juan José , Alzate Alfonso
Published: July 2024

This paper presents the methodological design and the laboratory test of neural net based power system stabilizer (PSS). The architecture of the proposed PSS uses two neural networks, one neural based controller which is used to generate a supplementary control signal to the excitation system, and an additional neural net used to improve the performance of the neural based controller. In order to guarantee the correct operation of the proposed PSS, it is trained by using data obtained from several machine operating conditions and a variety of disturbances. The effectiveness is demonstrated by testing the proposed approach in a real synchronous machine in a laboratory facility.
A Novel Routing Algorithm for Vehicular Ad Hoc Networks
Authors: Aquino-Santos Raúl , González-Potes Apolinar , Villaseñor Luis Armando , Edwards Arthur
Published: July 2024

This article examines the importance of wireless ad hoc networks and the Location Routing Algorithm with Cluster-Based Flooding (LORA-CBF) for inter-vehicular communication in the context of optimizing traffic flow and increasing motorway safety. The LORA-CBF routing algorithm is discussed and simulated in detail, considering a motorway environment with its associated high mobility. First, for small-scale networks, our proposed simulation model is validated with the results of a test bed. Then, for large-scale networks we use simulations to compare our model with both the Ad Hoc On-Demand Distance Vector (AODV) and Dynamic Source Routing (DSR) algorithms. We use a microscopic traffic model, developed in OPNET, to ascertain the mobility of 250 vehicles on a motorway. Finally, we apply LORA-CBF in a vehicular test bed.