bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study on Sound Analysis Algorithm for Heart Sounds using YOLO Deep Learning Model
Authors: Tamura Hiroki , Gunaratne Praveen Nuwantha , Takeguchi Hiromu , Fukumoto Hiroyuki , Hashiguchi Yoshifumi
Published: March 2024

As Japan’s population ages, the demand for home medical care is increasing. And, as the demand for home medical care increases, the burden on medical personnel becomes a problem. One of the ways to promote home medical care is to spread the use of medical equipment in households. However, since some medical knowledge is required to use basic medical equipment, it is considered difficult to spread the use of medical equipment among general households. Therefore, it demands the necessity to develop a medical device that can give the same decision as a medical doctor by using an algorithm. In this paper, we study the construction of an algorithm for an AI stethoscope that can make the same decisions as a medical doctor. We combine a frequency analysis method using three features and an image processing method using an image that represents the frequency features by wavelet transform. Using the results of each of these methods, we aim to improve the identification rate through machine learning techniques. The Random Forest training yields an identification rate of 94.68 ％ on the dataset of this paper.
Early Stunting Detection System for Toddlers Based on Height and Weight Using Backpropagation Neural Network Method
Authors: Ristanti Dini Eka , Syauqy Dahnial , Henryranu Prasetio Barlian
Published: March 2024

Stunting is a chronic nutritional problem characterized by height and weight problems. Toddlers who have height and weight of more than minus 2 standard deviations are at risk of suffering from stunting and require monitoring for 3 to 6 consecutive months. Currently, the system still measures toddlers' height and weight, then matches it with the World Health Organization(WHO) growth data table. Therefore, we proposed to develop a system to detect height and weight as well as the risk of stunting in toddlers using an ultrasonic sensor, load cell, and backpropagation algorithm. In its implementation, the ultrasonic sensor achieves an accuracy of 99%, and the load cell reaches 93%. The system uses backpropagation neural network method, which achieved an R of 0.99845 using 3 inputs, 16 hidden layers,1 layer for re-weighting, and 1 output layer. The mean squared error reaches 0.01 with 2 prediction classes, low risk, and high riskstunting. Overall, the total system accuracy can reach 97.75%.
Design of Soil Moisture Telemetry System Using cluster-based Wireless Sensor Networks
Authors: Utami Annisa Widuri Murti , Kartikasari Dany Primanita , Bhawiyuga Adhitya , Siregar Reza Andria , Bakhtiar Fariz Andri
Published: March 2024

Agriculture is an art and science used to cultivate the land, grow crops, and raise livestock. Agricultural land in Indonesia has different soil quality in each region. Soil quality for agriculture can have an impact on crops. Therefore, a Wireless Sensor Network (WSN) was created to make it easier to determine soil moisture. This system can help to monitor the condition of soil moisture content. WSN applies a Cluster-Based Algorithm, and the protocol used in WSN is a Low Energy Adaptive Clustering Hierarchy (LEACH). WSN will search for the cluster head, and then the sensor node will send the results of soil moisture sensing data to the cluster head for further data aggregation. Then, the results of the aggregation data will be sent to the sink node and then forwarded to the cloud. Data aggregation can make the sink stay longer than 30 minutes than the sink node that receives data without aggregation. Sink nodes that do not receive aggregation data also use more load current than sinks that receive aggregation data. The test results of the average response time to find new cluster heads have an average time of 6023.4 milliseconds. The maximum distance between nodes to transmit data to each other is 100 meters.
Development of Electrocardiogram Signal Generator for Fibrillation Detector
Authors: Siwindarto Ponco , Jason Bill , Muttaqin Adharul , Nurrohman Muhammad , Muis Muhram , Abidin Zainul
Published: March 2024

Fibrillation is one of the abnormalities in the heart where it beats irregularly, which can cause sudden death. Fortunately, these abnormalities can be detected using an electrocardiogram (ECG) fibrillation detector. An ECG can be detected as biopotential body signal that arises as a result of electrical activity of the heart muscle represented by the electrical signals consisting of P, Q, R, S and T waves that carry information about someone’s heart condition through graph pattern. However, a test in humans with the potential for fibrillation is needed to determine whether the fibrillation detector works correctly. Testing this way is ineffective because we cannot predict when and where a person will experience fibrillation. On the other hand, a site called PhysioNet provides various medical records from patients, including ECG signals of normal heartbeats, atrial fibrillations, and ventricular fibrillations. Because of the ineffectiveness of testing a fibrillation detector directly on a living person, this study focused on research to develop an ECG signal generator using microcontroller Arduino Due for reconstructing the heart signal in normal and fibrillated heart conditions collected from the PhysioNet database. The research focused on obtaining an R-peak value and RR interval time that resembled a heart ECG wave. This study compared the reconstructed signal with references from PhysioNet and measured the peak level of R and R-R interval time using an oscilloscope to calculate the accuracy of the ECG signal generator. The generated ECG signal during Atrial Fibrillation and Normal Sinus Rhythm has an overall accuracy of 88.65% for the R-peak level and 97.24% for the RR-Interval time. While Ventricular Fibrillation has been reproduced by achieving amplitude errors of less than 5.63% and 10.22% during first and second samples, respectively.
Correlations on the southern Kaapvaal Craton Margin, 1: Ventersdorp lavas transgressed the Doornberg lineament
Authors: Cornell D.H. , Meintjes P.G. , van der Westhuizen W.A. , Kristoffersen M.
Published: March 2024

Two small exposures of quartz-porphyritic rocks occur on the farm Zoutpekel 98 in the Marydale Terrane between the Doornberg Fault and Brakbos Shear Zone, apparently overlying Kaapvaal basement granite but lacking clear field relationships due to sand and Dwyka tillite cover. They are lavas and tuffs, metamorphosed in lower amphibolite facies. They contain quartz phenocrysts with a distinctive blue colour, due to metamorphic exsolution of rutile. Microbeam U-Pb zircon dating gives a combined 207Pb/206Pb age of 2 722 ± 3 Ma (seven determinations on four samples), interpreted as the age of extrusion. Three of these samples give the same discordia upper intercept age, but one sample gives discordia intercepts of 2 688 ± 15 and 1 223 ± 120 Ma, thought to reflect metamorphic lead loss related to the ~1 210 Ma Namaqua terrane assembly collisions.

The Zoutpekel exposures are coeval with the 2 720 ± 2 Ma Makwassie Formation of the Platberg Group, Ventersdorp Supergroup. They also correspond geochemically to the Makwassie Formation and no other unit of the supergroup. A sample from the T’kuip Formation of the nearest Ventersdorp Supergroup inlier on the Kaapvaal Craton (east of the Doornberg Fault), gives an age of 2 716 ± 8 Ma, also confirming its lithostratigraphic and geochemical correlation with the Makwassie Formation.

The Zoutpekel exposures show that not only the Kaapvaal basement granites, but also the supracrustal cover rocks of the Ventersdorp Supergroup, extend southwards across the Doornberg Fault, The Marydale Terrane is thus not an exotic terrane, but probably represents a passive continental margin developed at the beginning of the 1 300 to 1 000 Ma Namaqua-Natal Wilson cycle.

The age range of the Ventersdorp Supergroup and the age and stratigraphic correlation of the Marydale Group thrust complex, which straddles the Zoutpekel exposures, will be investigated in two companion papers.
Satellite imagery reveals the nature of the Archaean granite-greenstone basement of the Kruger National Park, South Africa, including the newly discovered Olifants River Greenstone Belt
Authors: Anhaeusser C.R.
Published: March 2024

Archaean greenstone remnants comprising mainly metamorphosed basaltic lavas and lesser metasedimentary interlayers are components of the granite-gneiss-migmatite basement terrane of the central and northern parts of the Kruger National Park (KNP), South Africa’s premier wildlife nature reserve. Most of the greenstone remnants represent extensions into the Kruger Park of better developed and exposed greenstone belts that exist beyond the borders to the west, including the Giyani and Murchison greenstone belts. Geological mapping in the national park presents challenges as exposures are poor and discontinuous, with the dense bush and wildlife adding to the difficulties. Satellite remote sensing provided an ideal solution and in this study Google Earth imagery proved to be especially helpful. The imagery provides a synoptic overview of the terrane making it possible to establish the outline of greenstone remnants irrespective of the dense bush cover. Google Earth imagery furthermore provided a preliminary impression of a hitherto unknown, yet sizeable, greenstone belt remnant in a remote area south of the Olifants River in the central section of the KNP. Referred to as the Olifants River Greenstone Belt in this study the remnant occurs as a major Type 2 interference fold resembling a mushroom-shaped diapir with a broad bulbous core fringed by laterally flattened skirts. Images are presented that illustrate various components of this imposing structure. Google Earth images furthermore display the general character of the Archaean granite-greenstone basement and the Palaeo- and Mesoproterozoic intrusive dyke swarms on the northeastern flank of the Kaapvaal Craton.
Analyzing the Role of Social Workers in Supporting People Living With HIV in New York City During the 1990s
Authors:   Centre for Research in Psychology and Human Well-Being, Faculty of Social Sciences and Humanities, University Kebangsaan Malaysia, Malaysia, Shaari Azahah Abu Hassan , Zakaria Siti Marziah ,   Centre for Research in Psychology and Human Well-Being, Faculty of Social Sciences and Humanities, University Kebangsaan Malaysia, Malaysia, Rajaratnam Surendran ,   Centre for Research in Psychology and Human Well-Being, Faculty of Social Sciences and Humanities, University Kebangsaan Malaysia, Malaysia, Ijon Ruzaini ,   Faculty of Language Studies and Human Development, Universiti Malaysia Kelantan, Kelantan, Malaysia, Razak Ateerah Abdul ,   Faculty of Language Studies and Human Development, Universiti Malaysia Kelantan, Kelantan, Malaysia, Halim Wan Puspa Melati Wan Abdul ,   School of Liberal Arts and Sciences, Taylor’s University, Selangor, Malaysia, Waller Bernadine ,   Department of Psychiatry, Columbia University Irving Medical Centre, New York State Psychiatric Institute, New York, U.S.
Published: March 2024

Social workers play a crucial role in empowering people living with HIV (PLHIV) and their family members. This qualitative study aimed to reflect social workers’ experiences working with PLHIV in New York City in the 1990s. Using a qualitative narrative inquiry method and convenience sampling technique, two social workers who experienced working with PLHIV in New York City in the 1990s were interviewed for this study. Findings revealed that since the beginning of the epidemic, social workers have played crucial roles in providing a range of psychosocial services for PLHIV, including individual therapy and support groups. Furthermore, social workers acted as advocates who demanded social rights and social justice for the HIV population. Finally, social workers, in the early discovery of HIV, collaborated with the community of PLHIV to establish some of the early nonprofit organizations to overcome the structural barriers, including gender inequity and stigma, for PLHIV to live well.
The Construction and Definition Problems Surrounding the Political and Legal Ideal
Authors: Lykov Andrey Yurievich
Published: March 2024

The subject of this study is the concept of “political and legal ideal.” Guided by current statistical data and international research results, it is substantiated that the models of state development used in the world have turned out to be untenable. The consequence of this circumstance is the need for legal science to develop new approaches to improving social relations. A political and legal ideal can serve this purpose. Based on the study of legal doctrine and modern scientific works, the author has attempted to analyze the concept of the “political and legal ideal” and propose a possible way to construct it. The methodological basis of the work consists of a systematic approach, analysis, synthesis, dialectical method, eclectic method, formal legal method, and the method of state-legal modeling. Statistical and sociological methods are also applied to use factual data about society. The author’s unique contribution to the study of the topic is forming a new approach to understanding the political and legal ideal and its construction. When forming theoretical provisions that make up the content of the political and legal ideal, it is proposed to consider three groups of mandatory consistent patterns. The first and foremost group is characteristic of any state, the second is only for a group of states united by a common goal, and the third is patterns that are exclusive to a specific state. In addition, the content of the created model must reflect the immanence of contradictions in society and form a mechanism for their resolution. The approach presented by the author can serve as the basis for further improvement of the theory of the political and legal ideal, as well as contribute to the development of the most necessary effective legal solutions on the part of the state.
Forms of organization of people as a primary stage in relations with the state
Authors: Kitaeva Viktoriia
Published: March 2024

The article analyzes the legal and organizational foundations of interaction between public authorities and people. Local self-government is considered as a modern and most important form of organizing the activities of people, since it is the type of public authority closest to the population and is designed to solve issues of local importance in a particular territory. The subject of the study is the problems of interaction between public authorities and people due to the fact that at the present stage in our country there is an urgent demand for direct participation of people in solving issues of local importance, since active participation of people in the field is necessary to solve national issues. The methodological basis was general scientific and special research methods: formal legal, systemic, comparative legal analysis. For example, the formal legal method made it possible to analyze the main forms of local self-government, and the comparative legal method helped to conduct a comparative analysis of the forms of direct implementation of local self-government and forms of public participation in the implementation of local self-government. The purpose of the work is achieved by identifying and analyzing current problems of interaction between public authorities and people. Result of the research that not all forms of interaction between public authorities and people are equally effective. Some of them are outdated. The article concludes that there is a need for priority interaction of public authorities with people to resolve issues of local importance, as well as that it is the forms of organization of people that are the primary link in relations with the state. The authorities need to involve people in the development of territories and solving problems, interacting in various forms and implementing the most successful practices of the regions everywhere.
Journalistic cultures in the context of the conflict of civilizations
Authors: Georgieva Elena Savova , Blokhin Igor Nikolaevich , Oleinikov Sergei Viktorovich , Labush Nikolai Sergeevich
Published: March 2024

The subject of the research is journalism as a social institution. Modern media industries are becoming maximally polarized and involved in the process of promoting and defending certain values, as a result of which we see an unprecedented information confrontation that is one way or another transforming the world community. Media researchers are beginning to recognize the untenability of the idea of a universal culture in the field of journalism. Based on these premises, the object of the study was journalistic culture, which includes the choice of methods for collecting information and creating a media product. The work used axiomatic (the specificity of the method is that at the beginning of the process a set of basic provisions is specified that do not require proof and are taken as explicit, in fact, they are an axiom), analysis and synthesis, combining the conclusions obtained during the previous research method into a single whole. The novelty of the study is seen in the fact that for the first time, when studying the functions of journalism, a conclusion is drawn about the need to move away from globalization ideas from an axiomatic point of view. It can be observed that in recent years, social networks, instant messengers and channels, which are capable of completely reformatting the mentality of society and even the way people think, can have an increasing influence. Based on the results of the study, the following conclusions can be drawn: trends and communication flows are now created mainly in social networks and the services that support them, and communication is then effective when it actively unfolds in the online media space. Numerous social networks of different types, while entertaining, involve their audience in the communication process and offer the opportunity for cultural and political socialization.
Perception of Andrei Bely's works in China
Authors: Zhang Linlin
Published: March 2024

The paper examines the history of Chinese translations and studies of the artistic creativity and theoretical research of Andrei Bely, as well as comparative analysis of the works of Chinese literary scholars specializing in the study of poetry, prose, as well as the critical heritage of the Russian symbolist. The purpose of the work is to give a complete picture of the state of translations and the degree of knowledge of Bely’s heritage in China, as well as to summarize this existing material, which seems important for subsequent research in this area. In addition, the article traces the stages of development of the study of the works of Andrei Bely, special attention is paid to the perception of the novel Petersburg and its literary criticism by Chinese scholars. An attempt is being made to identify gaps in Chinese literary studies and thus highlight promising lines of development in this area of literary criticism. The work uses comparative historical method, which allows us to determine the influence of Russian modernism, represented by Bely, on the modern literary process in China. Translations of Bely's works into Chinese are not yet a fully studied problem in science, which determines the novelty of the research. It is shown how the approach to the translation of symbolist text has changed and improved, three groups of translations have been identified and considered (translations of poetry, theory and novels), with special attention paid to the translation of novels. As for research, despite the sufficient number of works on Bely in Chinese science, they cannot be considered exhaustive. Our work attempts to highlight both problem areas and achievements of Chinese Bely studies, consider various scientific approaches to understanding Bely’s prose, and concludes that it is necessary to expand scientific tools for a deeper understanding of Bely’s heritage.
Associations between interleukin-13, interleukin-4 and their receptor gene polymorphisms and susceptibility to atopic dermatitis in a Chinese Han population
Authors: Zhong Lian-Sheng , Chen Xiao-Yi , Xiao Jing
Published: March 2024

Background

Atopic dermatitis (AD) is a common skin condition that occurs due to a combined effect of immune dysregulation, skin barrier dysfunction, changes in the cutaneous microbiome, and genetic factors. Recent data from both clinical trials and real-world studies indicate that dupilumab, a biological agent that inhibits interleukin 4 receptor-α is an effective drug in the treatment of AD, which further suggests the important role of IL-13 and IL-4 in the pathogenesis of AD.

Objectives

To assess the association between gene polymorphisms of IL-13, IL-13 receptor, IL-4, and IL-4 receptor and susceptibility to AD.

Methods

The single nucleotide polymorphisms (SNPs) of the above-mentioned genes were detected by single base extension (SNaPshot) assay. The association between these SNPs and AD risk was analysed using SPSS software.

Results

Two hundred and seventy-one subjects including 130 patients with AD and 141 healthy controls were enrolled. There were statistical differences between AD patients and controls in genotype distribution at rs2265753, rs6646259, and rs2254672 of the IL-13 receptor gene (P all < 0.001). Subjects with CG at rs2265753, AG at rs6646259 and TG at rs2254672 had increased risks for AD (P all < 0.001), and subjects with GG at rs2265753, rs6646259, and rs2254672 had reduced risks for AD (P all < 0.001).

Limitation

This was a single-centre and single-race study, with a relatively small sample size.

Conclusions

Findings from this study show that rs2265753, rs6646259 and rs2254672 of the IL-13 receptor gene are associated with susceptibility to AD.
Secondary normal pressure hydrocephalus following pituitary apoplexy: A case report
Authors: Tomita Yusuke , Fukuda Shoichi , Kobashi Aiko , Okada Yoshihiro , Makino Keigo , Kidani Naoya , Muraoka Kenichiro , Hirotsune Nobuyuki , Nishino Shigeki
Published: March 2024

Background:

Although secondary normal pressure hydrocephalus (sNPH) can occur in various central nervous system diseases, there are no reports of sNPH caused by pituitary lesions. Herein, we present a unique case of sNPH caused by pituitary apoplexy.

Case Description:

A 70-year-old man was transferred to our hospital because of a sudden onset of headache and loss of consciousness. The cerebrospinal fluid (CSF) test showed slightly elevated cell counts and protein levels but a negative CSF culture test. Magnetic resonance imaging showed a dumbbell-like cystic lesion with hemorrhagic change at the sella turcica. From the above, the patient was diagnosed with aseptic meningitis caused by pituitary apoplexy. Pituitary hormone replacement therapy was undertaken, and his symptoms fully improved. However, two months later, he complained of a gait disturbance and incontinence that had gradually appeared. Brain imaging with computed tomography showed no ventricular enlargement compared with initial images, although the lateral ventricles were slightly enlarged. As a CSF drainage test improved his symptoms temporarily, sNPH with possible longstanding overt ventriculomegaly in adults (LOVA) background was suspected. We performed a lumboperitoneal shunt (LPS) placement, which improved his symptoms.

Conclusion:

This case suggests that sNPH can develop even after a small subarachnoid hemorrhage caused by a pituitary apoplexy in LOVA patients. If the aqueduct of Sylvius is open, sNPH with a LOVA background can be successfully treated with LPS placement.
A case report of an unusual cerebral hydatid cyst
Authors: Ahmed Mubasher , Basurrah Abdulaziz A. , Brinji Zaina Siraj , Albargi Naseem , EL-Fattah Mona Abd , Alnashiwaaty Omar , Aljohani Mona Shadad , Alkhotani Alaa , Farag Ahmed Adel
Published: March 2024

Background:

Intracranial hydatid cyst is an exceedingly uncommon condition. Typically, it manifests as hydatid cysts in the liver, lungs, kidney, and spleen. In this report, we present a rare case of a hydatid cyst located in the brain, exhibiting atypical radiological characteristics, and successfully treated with complete microsurgical excision.

Case Description:

A 45-year-old male, a former smoker, presented with a new-onset seizure. Brain imaging revealed a solitary, intra-axial, and cystic lesion with wall enhancement in the right temporal region. The cyst extended into the temporal horn of the right lateral ventricle, surrounded by mild edema. Differential diagnoses included brain metastasis, abscess, and tuberculoma. However, following computed tomography (CT) scans of the chest, abdomen, and pelvis (CAP) and serological tests, the provisional diagnosis included a hydatid cyst. The CT CAP showed diffuse non-specific cystic lesions of variable sizes in the liver and spleen, along with numerous bilateral pulmonary cysts. A right temporal craniotomy was performed, and the cyst was microsurgically excised without rupture. Microscopic and histopathological examination confirmed the presence of a hydatid cyst.

Conclusion:

Intracranial hydatid cyst is an extremely rare condition and should always be considered a possible differential diagnosis in cases of cerebral cystic lesions. Hydrodissection is the preferred surgical method for resection; however, in atypical cases such as the one described here, meticulous dissection of the cyst capsule from the brain parenchyma may be successful with minimal risk of intraoperative rupture.
Blood rheology: mechanisms of change
Authors: Муравьев А.В. , Тихомирова И.А. , Приезжев А.В. , Луговцов А.Е.
Published: March 2024

Условием нормальной жизнедеятельности организма является эффективный транспорт и доставка в органы и их тканевые микрорайоны кислорода и всего спектра веществ, необходимых для метаболизма. Это достигается скоординированной работой всех систем организма и в том числе крови, которая обладает уникальной текучестью и тем самым эффективно решает транспортные задачи. Интегральной реологической характеристикой крови является ее вязкость. Величина последней определяется рядом ключевых параметров, таких как вязкость плазмы, показатель гематокрита, напряжение и скорости сдвига, агрегация и деформируемость эритроцитов. Изменение этих 5 основных реологических характеристик крови и эритроцитов определяет текучесть крови и ее транспортный потенциал. В обзоре рассмотрены возможные причины и механизмы изменений указанного выше комплекса гемореологических характеристик или отдельных элементов как в норме, так и при патологии.

The efficient transport and delivery of oxygen and other metabolically necessary substances to the organs and their tissue microregions is crucial for the proper functioning of the body. All body systems, including blood, cooperate. Blood has a unique fluidity that helps it transport substances effectively. Blood viscosity is an integral rheological characteristic that determines its flow properties. The value of blood viscosity is determined by several critical parameters, including plasma viscosity, hematocrit, stress and shear rates, and the aggregation and deformability of erythrocytes. The alteration of these 5 essential rheological characteristics has a significant impact on the fluidity of blood and its transport potential. The article discusses the potential causes and mechanisms responsible for altering the complex of hemorheological characteristics or individual components,both in normal and abnormal conditions.
Victim behavior in hemophilia patients
Authors: Королева А.А. , Полянская Т.Ю. , Выборных Д.Э. , Зоренко В.Ю.
Published: March 2024

У больных с тяжелыми наследственными заболеваниями, в том числе при гемофилии, нередко наблюдается развитие различных психических нарушений, среди которых, как правило, преобладают депрессия и повышенная тревожность. Наименее изучена на сегодняшний день у больных гемофилией проблема виктимного поведения, что в большинстве случаев сопряжено с повышенной травматизацией и значимым снижением качества жизни. Представлены 4 клинических случая больных гемофилией с различными типами виктимного поведения: паранойяльный, диссоциативный, диссоциальный, зависимый. У больных с виктимностью была отмечена низкая приверженность к лечению, повышенная травматизация и значимое снижение качества жизни. В зависимости от типа виктимности подробно описаны причины получения травм: агрессивное поведение, роль пассивной жертвы, игнорирование опасных ситуаций и создание регулярных конфликтных ситуаций. Показано, что наличие виктимного поведения у больных гемофилией оказывает значительное влияние на здоровье и риски травматизации. Необходимо разрабатывать стандартизированные инструменты оценки для диагностики виктимного поведения, позволяющие в дальнейшем минимизировать провоцирующие факторы для каждого типа виктимности у больных.

Patients with severe hereditary diseases, including hemophilia, often develop various mental disorders, with depression and increased anxiety being the most common. The issue of victim behavior in patients with hemophilia has been least studied to date, which in most cases is associated with increased trauma and a significant reduction in quality of life. We present 4 clinical cases of hemophilia patients with different types of victim behavior: paranoid, dissociative, antisocial, and dependent. Patients with a victim mentality exhibit low adherence to treatment, increased trauma, and a significant reduction in their quality of life. The causes of injury, depending on the type of victimization, are described in detail, including aggressive behavior, the role of a passive victim, ignoring dangerous situations, and creating regular conflict situations. Victim behavior in patients with hemophilia has been shown to have a significant impact on health and the risks of injury. Standardized assessment tools should be developed for diagnosing victim behavior, which can minimize provoking factors for each type of victimization in patients.
#Info-cervo, un nouveau type d'outil pour un cerveau synchronisé
Authors: Dorthe Catherine
Published: March 2024

Cet article présente les résultats et les implications d'un projet novateur appelé #info-cervo, qui explore les liens entre les neurosciences, la création artistique et la promotion de la santé chez les jeunes. En s'appuyant sur les observations faites lors d'ateliers de rap, l'auteur examine comment le processus de création de #info-cervo traverse les quatre filtres de l'attention du cerveau, tels que décrits dans l'ouvrage de Bourassa et al. (2021). En mettant en lumière les résultats des évaluations des jeunes et des professionnels, l'article démontre l'impact positif de #info-cervo sur la prise de conscience des jeunes de leurs propres capacités, ainsi que sur la promotion de leur auto-efficacité en matière de santé. En conclusion, l'auteur discute des limites du projet, de ses implications pour la pratique professionnelle et des perspectives d'avenir pour #info-cervo dans le domaine de la promotion de la santé des jeunes.
Classification of Depressed and Nondepressed Girls by Stress Load, Stress Coping, and Activity of HPA Axis
Authors:   University of Trier, Trier, Germany, L Reinhold , S Ulrike ,   University of Trier, Trier, Germany
Published: March 2024

Based on former empirical studies and theoretical considerations the present study investigated differences in stress load and stress coping between adolescent girls with major depression and controls. In addition a biological indicator of chronic stress (the cortisol awakening response) was measured. 148 girls with a mean age of 15 years were studied. 74 fulfilled DSM IV criteria for major depression. Stress symptoms and stress coping was measured with SSKJ 3-8 and SVFKJ which are validated German questionnaires. Depressed girls reported a significantly higher stress load and significantly more destructive stress coping. A classification in depressed and nondepressed girls was done by discriminant analysis. Stress load, stress coping, and cortisol awakening response were used as predictors. Canonical correlation coefficients were used to evaluate classification. When passive avoidance was included in the analysis, the best discriminant function could be obtained.
The Effectiveness of Play Therapy Intervention in Developing Social Skills for Children with Autism Spectrum Disorder: Meta-Analysis
Authors:   Department of Medicine, Alfaisal University, Clinical Psychology, Saudi Arabia, MS Alghslan , H Mohamed ,   Department of Mental Health, Certified Clinical Psychologist, Board Certified Behavior Analyst, Psychology Section, King Fahad Medical City, Saudi Arabia
Published: March 2024

The present study will examine existing data on the effectiveness of play therapy on the development of social skills in young children with Autism Spectrum Disorder (ASD). As the prevalence of ASD diagnoses continues to rise, families and educators are faced with critical decisions about the selection and provision of evidence-based approaches, as well as a need for knowledge on the approach to disability and help with long-term management planning. The following study analyzes the effectiveness of Play Therapy Intervention in building Social Skills for Children with Autism Spectrum Disorder using statistical evidence. The researcher used SPSS software to conduct statistical analyses to estimate effect sizes across the available data for the effectiveness of play therapy to foster social development in young children with ASD from 1 to 14 years old. The results revealed that play-based interventions are considered an effective intervention to support social development in young children, and type of play-based intervention as significant predictors of social development for young children with ASD who participate in play-based interventions. Such findings offer insights for families, clinicians, support providers, and decisionmakers that are purposely addressed in this analysis for their central role in the guidance in the implementation of various behavioral interventional modalities for ASD which aim to develop their social skills.
The Effectiveness of Play Therapy Intervention in Developing Social Skills for Children with Autism Spectrum Disorder: Meta-Analysis
Authors:   Health Emergency Operations Center (HEOC), Ministry of Health and Social Action (MHSA), Senegal, I Diagne , V Petit ,   French Research and Development Institute, UMR 196 CEPED, University of Paris: 45 rue des Saints Peres 75006 Paris, A Koundoul ,   Emile Badiane Psychiatric Center of Ziguinchor, Senegal
Published: March 2024

The mental health of young people is an issue of public health and sustainable development that is still underestimated in the countries of the South, particularly in sub-Saharan Africa, even though demographic and health transitions make it a major challenge. The overview of mental health in developing countries highlights the absence of a specific policy, the lack of resources allocated to this health sector, and the scarcity of research, even though mental illnesses have decisive and growing morbid, social, and economic impacts. The insufficient production of data contributes to the invisibilities of this issue. Based on the literature and the experiences of the authors on mental health in Senegal, they illustrate how the psychological health of young people is interwoven into the societal context.
Assessment of Factors Affecting for Adoption of Agroforestry by Local Communities of Vaishali, Bihar, India
Authors:   Department of Environmental Science, Magadh University, Bodhgaya, Bihar, India, Kumar Rajeev , Singh Pushpa ,   Department of Botany, A.N. College Patna, Patliputra University, Bihar, India, Barik Saroja Kumar ,   Department of Environment, Forest and Climate Change, Patna, Bihar, India, Pandey Jyoti ,   Department of Botany, A.N. College Patna, Patliputra University, Bihar, India
Published: March 2024

Agroforestry is considered one way to avoid deforestation to reduce CO2 emissions into the atmosphere and mitigate climate change. Deforestation is a serious problem in many developing countries, mainly due to subsistence and commercial agriculture. The present study complemented the secondary data related to Agroforestry schemes adoption with household surveys and key informant interviews to obtain evidence from farmers and promoters of the schemes on the factors affecting adoption the of agroforestry by the local community of Vaishali, Bihar. Based on data analysis and parameter estimates value, the three most important factors as Socio-Economic Level (Livestock, Income Level); External Unforeseen Factors (Protection from Wild Animals, Insects, Climate), and Economics of Business (Market Availability) impacting the Adoption of Agro-forestry Schemes (AAS) in Vaishali, Bihar.
The Tetrahymena Paradigm: Genetic Insights and Ecotoxicity Assessment
Authors:   Associate Professor, Department of Environmental Science and Occupational Safety and Health, Tajen University, Pingtung, Taiwan, Lee Yu-Ru , Lai Mei-Cho ,   Associate Professor, Department of Pharmacy and Master’s Program, Tajen University, Pingtung, Taiwan, Liu Hsiao-Han ,   Assistant Professor, Department of Medical Science and Biotechnology, I-Shou University, Kaohsiung, Taiwan, Chen Jung-Ren ,   Associate Professor, Department of Medical Science and Biotechnology, I-Shou University, Kaohsiung, Taiwan
Published: March 2024

Tetrahymena, a ciliated protozoan, thrives in freshwater habitats across diverse climates. Its importance as a genetic model organism lies in its cellular complexity, with cells comparable to human cells and a genome size between yeast and human. Tetrahymena’s germline genome undergoes unique chromosome breakage and DNA elimination, shedding light on genome rearrangement mechanisms. In 2020, the macronuclear genome was fully sequenced, offering improved insights into chromosome structure and gene models. Tetrahymena’s molecular tools enable gene characterization, knockouts, and overexpression. Beyond genetics, Tetrahymena serves as an ecotoxicity model, particularly Tetrahymena pyriformis. Changes in its morphology, food vacuole formation, and contractile vacuole response serve as toxicity indicators. Tetrahymena’s unique nuclear dimorphism (micronucleus and macronucleus) adds depth to ecotoxicological research. Additionally, Tetrahymena’s behavioral endpoints, including chemotaxis, phagocytosis, and motility, offer sensitive toxicity markers. Researchers have developed a T-maze toxotactic assay, a quick tool for studying Tetrahymena’s behavioral responses to different chemicals. Tetrahymena’s phagocytosis and motility are influenced by exposure to toxicants, reflecting changes in ion channels. Tetrahymena’s rapid movement makes it ideal for studying motility alterations caused by toxic substances. AI-driven tools enhance Tetrahymena behavior studies, allowing for behavior classification, feature extraction, and predictive modeling. This interdisciplinary approach aids in understanding Tetrahymena’s intricate behaviors, offering potential applications in gene discovery and pharmacological interventions. In conclusion, Tetrahymena stands as an invaluable model organism for genetic and ecotoxicological research. Its advantages, including genetic tractability and behavioral sensitivity, contribute to our understanding of fundamental biological processes and chemical safety assessment, with AI playing a growing role in advancing this field.
Leber Optic Neuropathy and Low Vision Rehabilitation: A Case Report
Authors:   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco, Ihssan Hasnaoui , Zahira Hazil ,   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco, Hassina Salma ,   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco, Amine Krichen ,   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco, Serghini Louai ,   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco, Elhassan Abdellah ,   Department of Ophtalmologie B & Faculty of Medicine and Pharmacy, Hospital of Specialities, CHU ibn Sina, University Mohamed V, Rabat, Morocco
Published: March 2024

Leber’s Hereditary Optic Neuropathy (LHON) is a maternally inherited mitochondrial disease, characterized by point mutations in mitochondrial DNA and subsequent mitochondrial dysfunction; which leads to a bilateral and painless loss of central vision. Unfortunately at this time, there is no proven treatment to prevent or reverse this optic neuropathy. Therefore, individualized low vision rehabilitation services and assistive devices are essential to help people with LHON regain their independence and quality of life. We highlight through a case study the importance of psychic support as well as the impact of low vision rehabilitation on a young man with LHON.
Implementation of a LC-MS based multi-attribute method (MAM) and intact multi-attribute method (iMAM) workflow for the characterisation of a GLP-Fc fusion protein.
Authors: Buckley Ciarán , Millán-Martín Silvia , Carillo Sara , Füssl Florian , MacHale Ciara , Bones Jonathan
Published: March 2024

Over the past few years, the implementation of mass spectrometry (MS) in QC laboratories has become a more common occurrence. The multi-attribute method (MAM), and emerging intact multi-attribute method (iMAM), are powerful analytical tools utilising liquid chromatography−mass spectrometry (LC-MS) methods that enable the monitoring of critical quality attributes (CQAs) in biotherapeutic proteins in compliant settings. Both MAM and iMAM are intended to replace or supplement several conventional assays with a single LC-MS method utilising MS data in combination with robust, semi-automated data processing workflows. MAM and iMAM workflows can also be implemented into current Good Manufacturing Practices environments due to the availability of CFR 11 compliant chromatography data system software. In this study, MAM and iMAM are employed for the analysis of 4 batches of a glucagon-like peptide-Fc fusion protein. MAM approach involved a first the discovery phase for the identification of CQAs and second, the target monitoring phase of the selected CQAs in other samples. New peak detection was performed on the data set to determine the appearance, absence or change of any peak. For native iMAM workflow both size exclusion and strong cation exchange chromatography were optimized for the identification and monitoring of CQAs at the intact level.
Inducible protein expression in stably transfected cells paves the way toward in-cell NMR studies in defined physiological states and 3D tissue cultures.
Authors: Trantirek Lukas , Foldynova-Trantirkova Silvie , Rynes Jan , Istvankova Eva , Krafcikova Michaela , Luchinat Enrico , Barbieri Letizia , Banci Lucia , Kamarytova Kristyna , Loja Tomas , Fafilek Bohumil , Rico-Llanos Gustavo , Krejci Pavel , Macurek Libor
Published: March 2024

In-cell NMR spectroscopy is the sole technique for characterizing protein structure, dynamics, and interactions in living human cells at atomic resolution. However, its applications have been restricted to asynchronous single-cell suspensions. We developed a strategy based on target protein inducible overexpression in stably transfected cells, allowing the acquisition of high-resolution in-cell NMR spectra in physiologically defined cellular states and 3D tissue models.
Urban and Regional Migration Estimates, Fourth Quarter 2023 Update
Authors: Whitaker Stephan D.
Published: March 2024

This Data Brief updates the figures that appeared in “Urban and Regional Migration Estimates: Will Your City Recover from the Pandemic?” with data for 2023:Q4 for all series. Migration estimates enable us to track which urban neighborhoods and metro areas are returning to their old migration patterns and where the pandemic has permanently shifted migration trends.
The Failure of the Bank of the Commonwealth: An Early Example of Interest Rate Risk
Authors: Prescott Edward S.
Published: March 2024

This Economic Commentary describes the collapse and subsequent bailout of the Detroit-headquartered Bank of the Commonwealth in 1972. Commonwealth failed because it invested heavily in long-duration, fixed-rate municipal securities in the mid-1960s in a bet that interest rates would decline. Instead, with the beginning of the Great Inflation of 1965–1980, rates rose. Liquidity problems then ensued, and the bank approached failure. Unable to find an acquirer because of Michigan’s banking restrictions, regulators instead bailed out the bank because of fears of contagion. This article also compares the collapse of Commonwealth with the spring 2023 failures of Silicon Valley Bank and First Republic. In particular, I discuss structural changes in banking that impacted the speed of the runs and the pools of potential acquirers.
Serverless Deployment Methodologies: Smooth Transitions and Improved Reliability
Authors:   Senior Manager Engineering, Clara Analytics, United States, Tripathi Ashutosh
Published: March 2024

The advancement of cloud computing has opened doors to serverless architectures, granting developers the freedom to create and launch applications without the burden of server management. This paper explores different approaches to deploying serverless applications, namely All-At-Once Deployment, Blue-Green Deployment, Canary Deployment, A/B Testing, and Shadow Deployment. Each method is thoroughly examined to grasp its approach, advantages, and ideal usage scenarios, offering a detailed roadmap for organizations seeking to enhance their deployment workflows for improved efficiency, dependability, and reduced downtime.
Examining Multicultural Representation in Lepus Songket of Palembang
Authors: Hutadjulu Dicky Maryoga
Published: March 2024

  

                        Sriwijaya in the 7th  century well known as Svarnadwipa that means island of gold. The Richness of gold made the kingdom produce woven fabric with golden thread called, songket.  

                        Lepus Songket is the ultimate songket in Palembang. Lepus has meaning covering , all the gold threads covered the whole fabrics.  

                        This article explains about the multicultural representation of Lepus Palembang songket. The examination of multicultural that influenced Lepus Songket would be presented. Lepus history is interesting, since the origin of it came from royalty family.  

The conclusion of this article suggest Lepus songket of Palembang is the precious multicultural legacy. The young generation should be the preserver of Lepus.  
Peranan Inyiak Upiak palatiang Dalam Melestarikan Pencak silat di Nagari Gunung, Kota Padang Panjang (1975-2010)
Authors: Lestari Silvia Dewi
Published: March 2024

Penelitian ini bertujuan untuk mengetahui riwayat hidup Inyiak Upiak Palatiang, untuk mengetahui peranan Inyiak Upiak Palatiang untuk melestarikan pencak silat di Nagari Gunung Kota Padang panjang, untuk mengetahui karakteristik pencak silat Inyiak Upiak Palatiang. Penelitian ini menggunakan metode sejarah yaitu seperangkat aturan atau prinsip sistematis untuk mengumpulkan sumber-sumber sejarah secara efektif, menilainya secara kritis, dan mengajukan sintesis atas hasil-hasil dicapai dalam bentuk tulisan. Adapun langkah-langkah dalam penulisan sejarah ini yaitu: (1) Heuristik merupakan sebuah kegiatan mencari sumber-sumber untuk mendapatkan data-data baik secara lisan maupun tulisan. (2) verifikasi adalah kegiatan dalam penelitian sejarah yang dilakukan secara memeriksa, mengoreksi dan menilai sumber-sumber sejarah yang telah dikumpulkan. (3) interpretasi merupakan menafsirkan fakta sejarah dan merangkai fakta tersebut hingga menjadi satu kesatuan yang masuk akal. (4) Historiografi merupakan tahap akhir dari penelitian ini. Hasil dari penelitian ini menunjukkan bahwa peranan Inyiak Upiak Palatiang untuk melestarikan pencak silat yang ada di Nagari Gunung Kota Padang Panjang, pernanan Inyiak Upiak Palatiang terlihat jelas dengan mengajarkan kepada generasi muda untuk tetap belajar silat, supaya pencak silat yang ada di Minangkabau ini tidak akan pudar.