bluuebunny/crossref_metadata_2025 huggingface dataset:
Middle East Success Story with World's First Adaptive Drill Bit and Premium Rotary Steerable Technology
Authors: Al-Enezi Dakhil , Gholoum Saleh , Al-Hajeri Mishari , Mohammed Jassem , Al-Enezi Reem , Deori Rupam , Pandya Mehul , Omar Marwa , Agawani Waleed , Valbuena Franklin , Abdelhamid Atef
Published: November 2018

The oil and gas industry has experienced multiple market surges and declines over the past decades. The latest downturn further assures the industry's nature of ‘change.’ Technology plays a key role in the management of change, allowing operators to maximize Return on Investment (ROI) through Cost per Foot (CPF) minimization. The adaptive drill bit was introduced to meet a major drilling operator's increasing demand for enhanced drilling efficiency and Non Productive Time (NPT) reduction.

The ‘adaptive drill bit’ embodies a hydro-mechanical apparatus and is entirely autonomous, requiring no input from surface as the system takes action to adapt downhole. Prior to the introduction of this exclusive technology, drill bits have been static devices, incapable of altering their characteristics in response to changes in formation or downhole loading conditions. The smart feature mitigates drilling vibration and hence improves drilling efficiency.

In the subject application, the 12.25-in. intermediate curved section is formed of challenging interbedded lithology [20-30K UCS], known to induce high drilling vibration levels. The high drilling vibrations typically jeopardize tools/rig components reliability and reduce drilling energy efficiency, leading to delayed section delivery and NPT. A diverse international team was appointed to develop an optimized solution for this market opportunity. The team introduced the adaptive drill bit and a premium technology Rotary Steerable System (RSS) combined solution to overcome the high torsional vibrations challenge and improve drilling energy efficiency.

In Kuwait, the first field deployment of the optimized solution reduced vibration levels by 33% and raised Rate of Penetration (ROP) by 42% from average field performance. The adaptive drill bit and RSS drilled at an average ROP of 44.3 ft/hr through approximately 2,500 feet building from 0 to 35 degrees at minimal steer force, offering 14% ROP leverage from competitor's best. The section was safely delivered one day earlier than offsets with zero NPT. Furthermore, the operator has requested for the technology utilization in three new drilling applications.
The Drive to Improve Water Quality via Conservation Adoption: Who's at the Wheel and Where Are We Headed?
Authors: Sharpley Andrew
Published: November 2018

Core Ideas

Public impacted by water impairment feels insufficient change within agriculture.

Change by litigation begs the question: Who's at the wheel and where are we headed?

Much litigation has a local focus but broad implications to agriculture.

Agricultural stakeholders must proactively advocate environmental stewardship.

Food service companies are driving change and widening the sphere of who pays.

Despite conservation practice (CP) adoption over the last 20 years, less than expected improvement in water quality has led some to question whether farmers are doing enough or have implemented appropriate CPs. As a result, environmental action groups have called for expansion of more restrictive land management measures. Based on the number of lawsuits from non‐agricultural against agricultural stakeholders, those affected by water quality impairment feel agriculture has changed little. Much litigation is based on geographically localized concerns, although the broader implications to agriculture are immense. In most cases, litigation has increased divisiveness among stakeholders. Thus, agriculture must advocate sound, sustainable environmental stewardship, which includes metrics that transparently track CP adoption and outcomes. Even though cost‐effective CPs are available that decrease nutrient loss under a range of settings, it will be increasingly costly and challenging to decrease losses further to achieve reduction goals to mitigate water quality impairment.
Impact of the North Atlantic Oscillation on Swedish Winter Climate and Nutrient Leaching
Authors: Ulén Barbro , Lewan Elisabet , Kyllmar Katarina , Blomberg Maria , Andersson Stefan
Published: November 2018

The winter climate in northwestern Europe is commonly influenced by the North Atlantic Oscillation (NAO). Its intensity, expressed as an index (NAOi), has been suggested for use in assessing nutrient leaching from arable land to water and the effects of mitigation measures. We found significant (p < 0.05) positive linear relationships between NAOi and an air freezing–thawing index in central and southern Sweden for 2004 to 2016. This period covered winters with both extreme low and high NAOi. There were significant negative linear relationships between NAOi and a snow depth index. Management and nutrient leaching were studied simultaneously in two agricultural catchments (20.7 ha, code 11M; 788 ha, code M36) in southwestern Sweden. Catchments 11M (silty–clay soil) and M36 (sandy hills with a central, heavy clay plain) are both artificially drained. Total N and total P leaching increased significantly with winter (November–April) NAOi in both catchments. In contrast, leaching of dissolved reactive P (DRP) was not related to NAOi. The highest DRP concentrations were observed in connection with specific agricultural practices, whereas moderately elevated DRP concentrations were linked to snowmelt events. Concentrations of P in other forms (other P) were even more elevated (1.02 mg L−1) in 11M in winter 2014–2015, probably due to a large (32% of area) internal buffer (ley–fallow) in a central ravine being plowed down in autumn 2014. No general trend in P or N fertilization was found in catchment M36. Thus NAOi may be appropriate for use in trend analyses of nutrient load in the study region.

Core Ideas

North Atlantic Oscillation (NAO) intensity index (NAOi) influences annual winter climate.

NAOi has an impact on regional nutrient leaching.

Moderate particle P leaching may reflect low NAOi and high snow depth index.

NAOi influences erosion less than ploughing down strategic unfertilized buffer zones.
High Yield Achieved by Early‐Maturing Rapeseed with High Light Energy and Temperature Production Efficiencies under Ideal Planting Density
Authors: Xu Zhenghua , Luo Tao , Rao Na , Yang Liang , Liu Jiahuan , Zhang Chunni , Hu Liyong
Published: November 2018

Early‐maturing rapeseed (Brassica napus L.) can alleviate the seasonal conflict between double‐season rice (Oryza sativa L.) and rapeseed in the Yangtze River basin. In this study, the early‐maturing rapeseed ‘Shengguang 127’ and intermediate‐maturing cultivar ‘Huayouza 9’ (control) were sown on 2 October under five different planting densities (150,000 [D1], 300,000 [D2], 450,000 [D3], 600,000 [D4], and 750,000 plants ha−1 [D5]) during two growing seasons. The patterns of change in growth and development, yield, and yield components were investigated systematically to reveal the light energy and temperature production efficiencies and to quantify the ideal plant density for the early‐maturing cultivar. The results showed that the early‐maturing genotype advanced the whole growth period by 3 to 5 d under the same densities, compared with those of the intermediate‐maturing genotype. The yield and population dry matter weight of both cultivars decreased after an initial increase, with the density increased initially from the D1 to D3 treatment, where it reached a maximum, and then decreased to the D5 treatment. Similar trends were observed in the light and temperature production efficiencies. Under the same densities, the production efficiencies of light energy and temperature in Shengguang 127 were 14.7 to 24.2% higher than those of the control, respectively; the yield and harvest indices in Shengguang 127 were significantly higher than those in Huayouza 9, which was attributed to the significantly higher 1000‐seed weight. These results provide a theoretical basis for the agronomic management and breeding of high‐yielding traits of early‐maturing rapeseed in the Yangtze River basin.
Water Movement and Finger Flow Characterization in Homogeneous Water‐Repellent Soils
Authors: Wang Yichen , Wang Xiaofang , Chau Henry Wai , Si Bingcheng , Yao Ning , Li Yi
Published: November 2018

Core Ideas

The cumulative infiltration decreased with increasing soil water repellency.

Soil water movement in higher water‐repellent levels tended to be more unstable.

Finger flow occurred preferentially in the coarser, more water‐repellent soils.

Strong correlations of cumulative infiltration and cumulative wetting area were shown.

Soil water repellency (SWR) is a widespread property in soils around the world. It influences soil water movement and causes unstable flow. The mechanics of finger flow occurrence in water‐repellent soils are not clearly understood. Slab chamber infiltration experiments consisting of increasing SWR persistence in clay and sandy loam soils were conducted to compare wetting front advancement and mechanics of finger flow development. The temporal variation curves of cumulative infiltration (CI) decreased with an increase in SWR persistence. For wettable soils, the wetting front advanced regularly with time, but for water‐repellent soils, it became unstable and finger flow occurred as the SWR persistence increased. Water movement in soils with higher SWR persistence tended to be more unstable. Water repellency contributed to finger flow development, especially for sandy loam. There were strong correlations among CI, finger length, and the cumulative wetting area. In the strongly, severely, and extremely water‐repellent sandy loam soils, the power function relationship fit better than the linear function. The average soil water content decreased with a higher SWR persistence, which meant that less water was available in the profile. Finger flow development was related to the more severe water‐repellent conditions and tended to be more easily formed in the water‐repellent sandy loam soils than the clay loam soils due to the faster infiltration rate.
Multi-objective calibration of MIKE SHE with SMAP soil moisture datasets
Authors: Li Dayang , Liang Zhongmin , Li Binquan , Lei Xiaohui , Zhou Yan
Published: November 2018

Root zone soil moisture plays an important role in water storage in hydrological processes. The recently launched Soil Moisture Active Passive (SMAP) mission has produced a high-resolution assimilation product of global root zone soil moisture that can be applied to improve the performance of hydrological models. In this study, we compare three calibration approaches in the Beimiaoji watershed. The first approach is single-objective calibration, in which only observed streamflow is used as a benchmark for comparison with the other approaches. The second and third approaches use multi-objective calibration based on SMAP root zone soil moisture and observed streamflow. The difference between the second and third approaches is the metric used to characterize the root zone soil moisture. The second approach applies the mean, which was commonly used in previous studies, whereas the third approach applies the hydrologic complexity μ, a dimensionless metric based on information entropy theory. These approaches are implemented to calibrate the distributed hydrological model MIKE SHE. Results show that the root zone soil moisture simulation is clearly improved, whereas streamflow simulation suffers from a slightly negative impact with multi-objective calibration. The hydrologic complexity μ performs better than the mean in capturing the features of root zone soil moisture.
Assessment of seasonal differences of ecological state of lotic ecosystems and applicability of some biotic indices in the basin of Lake Sevan (Armenia): case study of Masrik River
Authors: Asatryan V. L. , Dallakyan M. R.
Published: November 2018

Complex studies of seasonal differences of the ecological state of Masrik River (Armenia) were realized in 2017. Water quality was assessed by BMWP, ASPT and FBI indices based on studies of qualitative and quantitative structures of benthic macro-invertebrates. Potential reference sites in the basin were revealed using the %EPT taxa index in addition to water quality assessment by bioindication methods as well as hydro-chemical, -physical and -morphological measurements. The applicability of the used biotic indices for the different parts of Masrik River was discussed.
Autophagy Modulators and Neuroinflammation
Authors: Cho Kyoung Sang , Lee Jang Ho , Cho Jeiwon , Cha Guang-Ho , Song Gyun Jee
Published: November 2018

Background:

Neuroinflammation plays a critical role in the development and progression of various neurological disorders. Therefore, various studies have focused on the development of neuroinflammation inhibitors as potential therapeutic tools. Recently, the involvement of autophagy in the regulation of neuroinflammation has drawn substantial scientific interest, and a growing number of studies support the role of impaired autophagy in the pathogenesis of common neurodegenerative disorders.

Objective:

The purpose of this article is to review recent research on the role of autophagy in controlling neuroinflammation. We focus on studies employing both mammalian cells and animal models to evaluate the ability of different autophagic modulators to regulate neuroinflammation.

Methods:

We have mostly reviewed recent studies reporting anti-neuroinflammatory properties of autophagy. We also briefly discussed a few studies showing that autophagy modulators activate neuroinflammation in certain conditions.

Results:

Recent studies report neuroprotective as well as anti-neuroinflammatory effects of autophagic modulators. We discuss the possible underlying mechanisms of action of these drugs and their potential limitations as therapeutic agents against neurological disorders.

Conclusion:

Autophagy activators are promising compounds for the treatment of neurological disorders involving neuroinflammation.
Onion-Like Carbon Nanostructures: An Overview of Bio-Applications
Authors: Bobrowska Diana M. , Olejnik Piotr , Echegoyen Luis , Plonska-Brzezinska Marta E.
Published: November 2018

:

This article presents a brief review of the knowledge concerning onion-like carbons
(OLCs). These nanostructures are some of the most fascinating carbon forms due to their unusual
structure and physico-chemical properties. Generally, OLCs consist of a hollowspherical
fullerene core surrounded by concentric graphitic layers with increasing diameter.
Nevertheless, they can have different size, shape and type of core, which determine their
physicochemical properties. In this article, we review the most important literature reports in
this area and briefly describe these nanostructures, their physical and chemical properties and
their potential uses with a focus on biomedicine.
Dynamics of T Cells Repertoire During Trypanosoma cruzi Infection and its Post-Treatment Modulation
Authors: Egui Adriana , Lasso Paola , Pérez-Antón Elena , Thomas M. Carmen , López Manuel Carlos
Published: November 2018

Chagas disease courses with different clinical phases and has a variable clinical presentation and progression. The acute infection phase mostly exhibits a non-specific symptomatology. In the absence of treatment, the acute phase is followed by a chronic phase, which is initially asymptomatic. This chronic asymptomatic phase of the disease is characterized by a fragile balance between the host’s immune response and the parasite replication. The loss of this balance is crucial for the progression of the sickness. The virulence and tropism of the T. cruzi infecting strain together to the inflammation processes in the cardiac tissue are the main factors for the establishment and severity of the cardiomyopathy. The efficacy of treatment in chronic Chagas disease patients is controversial. However, several studies carried out in chronic patients demonstrated that antiparasitic treatment reduces parasite load in the bloodstream and leads to an improvement in the immune response against the Trypanosoma cruzi parasite. The present review is mainly focused on the cellular patterns associated to the clinical status and the evolution of the disease in chronic patients, as well as the effectiveness of the treatment related to T. cruzi infection control. Therefore, an emphasis is placed on the dynamics of specific-antigens T cell subpopulations, their memory and activation phenotypes, their functionality and their contribution to pathogenesis or disease control, as well as their association with risk of congenital transmission of the parasite.
Regulation of Histone Deacetylases by MicroRNAs in Bone
Authors: Shreya S. , Malavika D. , Priya V. Raj , Selvamurugan N.
Published: November 2018

Formation of new bone by osteoblasts is mediated via the activation of signaling pathways, such as TGF-β, BMP, and Wnt. A number of transcription factors participate in the signaling cascades that are tightly regulated by other regulatory factors. Histone deacetylases (HDACs) are one such class of regulatory factors that play an essential role in influencing chromatin architecture and regulate the expression of the genes that play a role in osteoblast differentiation by the mechanism of deacetylation. Four classes of HDACs have been identified namely, class I, class II A, class II B, class III and class IV. MicroRNAs (miRNAs) are small fragments of non-coding RNAs typically 19-25 nucleotides long that target mRNAs to upregulate or downregulate gene expression at a post-transcriptional level. A number of miRNAs that target HDACs in bone have been recently reported. Hence, in this review, we elaborate on the various miRNAs that target the different classes of HDACs and impact of the same on osteogenesis.
Graphene Family of Nanomaterials: Reviewing Advanced Applications in Drug delivery and Medicine
Authors: Joshi Kumud , Mazumder Bhaskar , Chattopadhyay Pronobesh , Bora Nilutpal Sharma , Goyary Danswrang , Karmakar Sanjeev
Published: November 2018

Graphene in nano form has proven to be one of the most remarkable materials. It has a single
atom thick molecular structure and it possesses exceptional physical strength, electrical and electronic
properties. Applications of the Graphene Family of Nanomaterials (GFNs) in different fields of therapy
have emerged, including for targeted drug delivery in cancer, gene delivery, antimicrobial therapy, tissue
engineering and more recently in more diseases including HIV. This review seeks to analyze current
advances of potential applications of graphene and its family of nano-materials for drug delivery and
other major biomedical purposes. Moreover, safety and toxicity are the major roadblocks preventing the
use of GFNs in therapeutics. This review intends to analyze the safety and biocompatibility of GFNs
along with the discussion on the latest techniques developed for toxicity reduction and biocompatibility
enhancement of GFNs. This review seeks to evaluate how GFNs in future will serve as biocompatible
and useful biomaterials in therapeutics.
Ablation of TRPV1 Elevates Nocturnal Blood Pressure in Western Diet-fed Mice
Authors: Zhong Beihua , Ma Shuangtao , Wang Donna H.
Published: November 2018

Background:

This study tested the hypothesis that genetically ablation of transient receptor potential vanilloid type 1 (TRPV1) exacerbates impairment of baroreflex in mice fed a western diet (WD) and leads to distinct diurnal and nocturnal blood pressure patterns.

Methods:

TRPV1 gene knockout (TRPV1-/-) and wild-type (WT) mice were given a WD or normal diet (CON) for 4 months.

Results:

Results: Capsaicin, a selective TRPV1 agonist, increased ipsilateral afferent renal nerve activity in WT but not TRPV1-/- mice. The sensitivity of renal sympathetic nerve activity and heart rate responses to baroreflex were reduced in TRPV1-/--CON and WT-WD and further decreased in TRPV1-/--WD compared to the WT-CON group. Urinary norepinephrine and serum insulin and leptin at day and night were increased in WT-WD and TRPV1-/--WD, with further elevation at night in TRPV1-/--WD. WD intake increased leptin, IL-6, and TNF-α in adipose tissue, and TNF-α antagonist III, R-7050, decreased leptin in TRPV1-/--WD. The urinary albumin level was higher in TRPV1-/--WD than WT-WD. Blood pressure was not different during daytime among all groups, but increased at night in the TRPV1-/--WD group compared with other groups.

Conclusions:

TRPV1 ablation leads to elevated nocturnal but not diurnal blood pressure, which is probably attributed to further enhancement of sympathetic drives at night.
Phenytoin Induced Chorea: A Rare Adverse Effect of the Drug
Authors: Patel Dhruvkumar M. , Gurumukhani Jayanti K. , Patel Mukundkumar V. , Patel Greshaben R.
Published: November 2018

Background:

Dyskinetic neurological diseases are common presentations of adverse reaction to many therapeutic agents. Phenytoin, a widely used age-old antiepileptic drug has been reported to cause dyskinesias, a rare Adverse Drug Reaction (ADR) in adults with toxic therapeutic serum level. When the drug is used in combination with other drugs which augments free drug level of phenytoin or in patients of organic brain lesion, this side effect is very occasionally reported with even normal therapeutic drug level.

Clinical Case:

We report a case of young male presented with chorea after two months of starting phenytoin for primary generalised epilepsy with normal therapeutic serum drug level. After excluding other differentials, drug-induced chorea was the final diagnosis. Despite phenytoin level was in therapeutic range, we have a trial of stopping Phenytoin with complete disappearance of chorea in 3 days. On reintroduction of phenytoin in the same dose, there was the reappearance of chorea in onemonth re-emphasising the diagnosis as “phenytoin-induced chorea”.

Conclusion:

If any patient on phenytoin develops any new neurological feature including dyskinesias, it should be considered as an ADR despite drug serum level within the normal therapeutic range.
Polysorbate 80 Coated Solid Lipid Nanoparticles for the Delivery of Temozolomide Into the Brain
Authors: Yadav Pawan , Rath Goutam , Sharma Gazal , Singh Ranjit , Goyal Amit Kumar
Published: November 2018

Introduction:

Anti-angiogenic therapy can produce transient regression in tumor in case of Glioblastoma (GBM); however, no prolongation of patient survival rate had so far been achieved.

Methodology:

To address this problem, an effort was made to design and characterize a temozolomide loaded nanosystem for targeting the tumor vasculature in the brain using polymeric nanoparticles. It included the formation of Temozolomide (TMZ) loaded Solid-Lipid Nanoparticles (SLNs) and their conjugation with polysorbate-80 (P-80) which enhanced the penetration of drug to blood-brain barrier resulting in the enhancement of pro-apoptotic activity.

Results:

Conjugating nanoparticles with a tumor-penetrating polymer (P-80) further enhanced the therapeutic efficacy of the drug.

Conclusion:

The animal studies indicated the enhanced potential of the developed system in the effective treatment of glioblastoma.
Epidemiology of Urinary Tract Infection in Neonatal Intensive Care Unit of Mohammed VI University Hospital in Marrakech
Authors: Lagrine Mariam , Bennaoui Fatiha , Slitine Nadia El Idrissi , Maoulainine Fadel Mrabih Rabou
Published: November 2018

Objective:

The objective of our study is to estimate the extent of urinary infection among neonatal infectious diseases.

Materials and Methods:

This work concerns a retrospective study of 91 newborns with urinary tract infections, collected in the Mohammed VI neonatal resuscitation unit, Marrakesh.

Results:

The average age of our newborns at admission was 10.8 days. In 20 cases, there were signs of maternal urinary tract infections. The main reason for hospitalization was jaundice in 72.53% of cases. The symptomatology was dominated by fever in 16.48% of cases, followed by a refusal to suck in 5.5% of cases. Escherichia coli was the predominant germ in 61.5% of cases. A probabilistic anti-biotherapy based on Ceftriaxone 3rd Generation and aminoglycoside was instituted in all cases after it was adapted to the antibiogram data. Ultrasound revealed malformations in 21 cases.

Conclusion:

Neonatal urinary tract infection remains a common pathology. Its potential severity involving renal functional prognosis and the frequency of urinary tract malformations require early diagnosis and adequate management.
Pollen morphology of selected taxa of Ehretiaceae from Western Ghats, India.
Authors: Michael Amalaurpava Mary , Gumma Vijay Gopal
Published: November 2018

Pollen Morphology is an important tool in the identification of a genera. Data on pollen morphology is used as a reference in other fields of palynology like allergic studies, melissopalynology, tracing the history of vegetation, genetic and evolutionary studies, climate change studies etc. Pollen morphology of two genera of Ehretiaceae family is studied using Scanning electron microscope. Palynological contributions are still fragmentary in the family Ehretiaceae of southern India. Ehretia pubescens Benth is a small tree belonging to Ehretiaceae family located at the foothill of Chamundi hill reserve forest which is a part of Western ghat near Mysuru and Cormona retusa (Vahl) Masam is a shrub found 3400ft above on top of Chamundi Hill. Pollen grains were acetolyzed and Scanning Electron Microscopic studies conducted to obtain data on pollen morphology. The study is conducted to assess the taxonomic significance of pollen morphology in relation to their phylogenetic origin of the two genera of Ehretiaceae in the region. The palynological evidence shows Ehretia pubescens with tri-zonocolporate and heterocolpate pollen grains and Cormona retusa with tricolpate pollen grain without the pseudocolpi. Both genera have foveolate tectum. Palynological data indicate that these two naturalized taxa ie. Ehretia pubescens and Cormona retusa belong to two different lineage of Ehretia and can be identified by their pollen morphology. Diversity in the pollen characters points towards the eurypalynous nature in Ehretiaceae.
TBS en Rapportage pro Justitia. Een historische beschouwing
Authors: Mooij A.W.M.
Published: November 2018

De wetswijziging in 1988 die leidde tot de naamswijziging van TBR in TBS, heeft geleid tot een aantal problemen met betrekking tot de rapportage pro Justitia. https://doi.org/10.21827/5a6b0da9d6269
Moet relationeel geweld apart strafbaar worden gesteld?
Authors: Lünnemann K.D.
Published: November 2018

https://doi.org/10.21827/5a6b2c93665f9
Hoe vertel ik het de Tweede Kamer?
Authors: Singer-Dekker H.
Published: November 2018

https://doi.org/10.21827/5a6b31bc0a9b1
Medische schaarste en het menselijk tekort
Authors: Jacobs Frans
Published: November 2018

https://doi.org/10.21827/5a6b329903272
Er is (n)iets mis met de maatregel TBS. Een overzicht van de recente ontwikkelingen
Authors: Raes B.C.M.
Published: November 2018

https://doi.org/10.21827/5a6b33bb94ff0
Risicotaxatie
Authors: Oppedijk Dick
Published: November 2018

https://doi.org/10.21827/5a6b33ecbf942
Recente ontwikkelingen en rechtspraak penitentiaire kamer Gerechtshof Arnhem
Authors: Otte M.
Published: November 2018

https://doi.org/10.21827/5a6b3c54aa56f
Jeugdige dader, volwassen straf?
Authors: Weijers I.
Published: November 2018

https://doi.org/10.21827/5a6b3defb4073
Wetsvoorstel deskundige in strafzaken
Authors: Hielkema J.
Published: November 2018

https://doi.org/10.21827/5a6b47f66c652
Het Penitentiair Psychiatrische Centrum: een volwaardige psychiatrische kliniek in de gevangenis?
Authors: Wesselius J.
Published: November 2018

https://doi.org/10.21827/5a6b49d43d329
Perspectives of People Who Are Overweight and Obese on Using Wearable Technology for Weight Management: Systematic Review (Preprint)
Authors: Hu Ruiqi , van Velthoven Michelle Helena , Meinert Edward
Published: November 2018

BACKGROUND

Obesity is a large contributor to preventable chronic diseases and health care costs. The efficacy of wearable devices for weight management has been researched; however, there is limited knowledge on how these devices are perceived by users.

OBJECTIVE

This study aimed to review user perspectives on wearable technology for weight management in people who are overweight and obese.

METHODS

We searched the online databases Pubmed, Scopus, Embase, and the Cochrane library for literature published from 2008 onward. We included all types of studies using a wearable device for delivering weight-loss interventions in adults who are overweight or obese, and qualitative data were collected about participants' perspectives on the device. We performed a quality assessment using criteria relevant to different study types. The Cochrane risk of bias tool was used for randomized controlled trials. The Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) was used for nonrandomized studies. The Oxman and Guyatt Criteria were used for systematic reviews. We used the critical appraisal checklist for qualitative studies. Data were extracted into a data extraction sheet and thematically analyzed.

RESULTS

We included 19 studies: 5 randomized controlled trials, 6 nonrandomized studies, 5 qualitative studies, and 3 reviews. Mixed perceptions existed for different constructs of wearable technologies, which reflects the differences in the suitability of wearable technology interventions for different individuals in different contexts. This also indicates that interventions were not often tailored to participants' motivations. In addition, very few wearable technology interventions included a thorough qualitative analysis of the participants' view on important features of the intervention that made it successful.

CONCLUSIONS

This study highlights the importance of determining the type of intervention most suitable for an individual before the intervention is used. Our findings could help participants find a suitable intervention that is most effective for them. Further research needs to develop a user-centered tool for obtaining comprehensive user feedback.

CLINICALTRIAL

PROSPERO CRD42018096932; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=96932
Higiene Sanitasi dan Uji Escherichia Coli Depot Air Minum Isi Ulang (Damiu) di Kelurahan Pesisir, Kecamatan Lima Puluh, Kota Pekanbaru
Authors: Mairizki Fitri , Hayu Riska Epina
Published: November 2018

Latar Belakang : Keberadaan DAMIU terus meningkat sejalan dengan dinamika keperluan masyarakat terhadap air minum walaupun tidak semua produk DAMIU terjamin keamanannya. Pemilihan DAMIU untuk memenuhi kebutuhan akan air minum beresiko bagi kesehatan jika konsumen tidak memperhatikan higiene sanitasi DAMIU.Tujuan : Mengetahui higiene sanitasi tempat, peralatan, operator dan uji Eschericia coli produk DAMIU di Kelurahan Pesisir, Kecamatan Lima Puluh, Kota Pekanbaru.  Metode : Jenis penelitian deskriptif dengan total sampling sebanyak 7 DAMIU. Penilaian higiene sanitasi menggunakan format pemeriksaan fisik berdasarkan pedoman penyelenggaraan higiene sanitasi DAMIU Kementerian Kesehatan. Kualitas bakteriologis diuji di laboratorium dengan persyaratan berdasarkan Permenkes RI No. 492/MENKES/KES/PER/IV/2010.Hasil : Kualitas bakteriologis air minum pada 7 DAMIU menunjukkan 1 DAMIU yang tidak memenuhi syarat dengan persentase 14% dan 6 DAMIU memenuhi syarat dengan persentase 86%.Kesimpulan : Secara umum higiene sanitasi tempat, peralatan, dan operator cukup baik, namun fasilitas sanitasi masih belum maksimal seperti belum adanya tempat cuci tangan yang  dan tempat sampah yang tertutup, operator tidak mencuci tangan setiap melayani konsumen dan tidak memeliki sertifikat kursus higiene sanitasi DAMIU.
Proposal of open field test as a model of varenicline pharmacokinetic study in rats
Authors: Zaccarelli-Magalhães Julia , Meira Sandini Thaisa , Rinaldi Fukushima André , De Souza Spinosa Helenice
Published: November 2018

Varenicline is a medication used for smoking treatment that acts as a partial agonist for nicotinic cholinergic receptors α4β2 and α3β4 and as a total agonist of receptor α7 in the central nervous system. Pharmacokinetic is important information for medications that acts in the central nervous system. This kind of assay is commonly done by expensive and complex analytical techniques. Therefore, the aim of this study was to evaluate the possibility of using the open field test as a pharmacokinetic model for varenicline in male rats exposed to a single dose of varenicline. Male rats received a single dose orally (gavage) of three different concentrations of varenicline: 0.03 (therapeutic dose for humans), 0.1 and 0.3 mg/kg or water (control group). The open field observations were recorded 30 min, 1, 2, 4, 6, 24, 48, 72 h and 7 days after the administration of varenicline or water. The results showed alterations in locomotion and rearing frequencies, as well as in immobility time observed in open field, which is consistent with this drug’s plasma peak. Consequently, this behavioral test apparently can be considerate as a model for pharmacokinetic evaluation of varenicline.
Avaliação da Educação Superior no Brasil - do Provao ao ENADE: um estudo meta-avaliativo
Authors: De Souza Francisco Jose , Souza Jurema Santos , Elliot Ligia Gomes , Hildenbrand Luci
Published: November 2018

O estudo teve como objetivo meta-avaliar o relatório apresentado ao Banco Mundial no ano de 2005, que trata das polÃ­ticas públicas de avaliação da educação superior implantadas no Brasil. No procedimento meta-avaliativo foi utilizada a Lista Chave de Verificação de Scriven (2007), apoiada nos critérios estabelecidos por Davidson (2005). Como resultado, o relatório demonstrou que houve melhoria nas avaliações da educação superior, mas que alguns pontos ainda carecem de determinados avanços. Entretanto, o estudo apontou que a utilização integral de todos os padrões do Joint Committee, pelos autores, possibilitaria acrescentar maior qualidade aos estudos avaliativos a serem realizados no futuro.Palavras-chave: Avaliação. Meta-avaliação. Padrões de avaliação. Lista Chave de Verificação.
PEMAKNAAN KREDIBILITAS KOMUNIKATOR ( Kasus pada Fasilitator PNPM Mandiri Perdesaan Desa Teluk Kecamatan Pemayung Kabupaten Batang Hari)
Authors: Muchlis Fuad
Published: November 2018

Tujuan penelitian ini adalah mengungkap makna kredibilitas fasilitator (dalam hal ini sebagai komunikator) menurut perspektif partisipan dan pelaku program pada implementasi PNPM MPd di lokasi penelitian. Paradigma yang dipilih dalam penelitian ini adalah paradigma kontruktivis. Lokasi penelitian berada di Desa Teluk Kecamatan Pemayung Kabupaten Batang Hari. Waktu penelitian dilaksanakan sejak tanggal 11 Maret 2009 sampai dengan tanggal 30 Juli 2009. Data dalam penelitian ini dianalisis secara kualitatif. Analisis data kualitatif adalah upaya yang berlanjut, berulang dan terus menerus. Analisis data dalam penelitian ini berlangsung bersamaan dengan proses pengumpulan data, meliputi tiga jalur, yaitu reduksi data, penyajian data dan penarikan kesimpulan.Hasil penelitian menunjukkan bahwa   kredibilitas fasilitator perspektif masyarakat penerima program (partisipan) dimaknai sebagai sosok yang memiliki kompetensi, berkarakter, karismatik; dan adaftif. Sementara itu dari perspektif pelaku PNPM MPd dapat disimpulkan bahwa kredibilitas fasilitator  menurun jika dibandingkan dengan program sebelumnya (PPK). Hal ini disebabkan oleh (1) semakin longgarnya syarat rekruitment calon fasilitator PNPM MPd jika dibandingkan dengan PPK. dan (2) PPK memberikan pelatihan pra tugas yang relatif cukup bagi calon fasilitator sebelum diturunkan ke lapangan dibandingkan pada PNPM MPd sehingga praktis pelatihan hanya mampu memberikan materi teknis. Kredibilitas yang cenderung menurun ini dikhawatirkan akan berdampak pada tidak efektifnya peran fasilitator dalam menjalankan dan mengawal program bervisi pemberdayaan.
ANALISIS STRATEGI BAURAN PEMASARAN DAN PENGARUHNYA TERHADAP VOLUME PENJUALAN AGROINDUSTRI KERUPUK KULIT (JANGEK) DI KOTA JAMBI
Authors: Ningrum Indah Uziyanti , Malik Adlaida , Kernalis Emy
Published: November 2018

Penelitian ini bertujuan untuk (1) menentukan strategi bauran pemasaran Kerupuk jangek pada Agroindustri di Kota Jambi, (2) mengetahui pengaruh strategi bauran pemasaran terhadap volume penjualan kerupuk jangek di Kota Jambi. Data yang digunakan adalah data pada Januari - Agustus 2012 selama ± 8 bulan terakhir (25 minggu), dimana data tersebut dikumpulkan secara kumulatif per minggunya. Data yang dikumpulkan terdiri dari data primer (observasi, interview) dan data sekunder. Data disusun, diolah dan dianalisis secara deskriptif kuantitatif dan diperkuat dengan analisis preferensi konsumen dengan melakukan uji inderawi sesuai dengan variabel yang diteliti. Untuk metode kuantitatif dalam penelitian ini menggunakan analisis Regresi Linier Berganda yang mencakup aspek biaya promosi, biaya distribusi dan volume penjualan melalui hasil wawancara menggunakan kuisoner. Hasil penelitian menunjukkan bahwa dengan nilai R2 sebesar 72,5% yang menunjukan variasi volume penjualan dapat dijelaskan oleh variasi biaya promosi dan distribusi sedangkan  27,5 % dijelaskan oleh faktor lain. F hitung (28.962  ) > F tabel (3,47) sehingga hipotesis diterima yang berarti secara keseluruhan promosi, dan distribusi berpengaruh nyata terhadap volume penjualan kerupuk jangek. Kata Kunci : Strategi Bauran Pemasaran (Promosi, Distribusi), Volume Penjualan
ANALISIS KONSUMSI PANGAN RUMAH TANGGA PETANI KARET DI KECAMATAN BATIN XXIV KABUPATEN BATANGHARI
Authors: Susanti Ling Ling , Damayanti Yusma , Nurchaini Dewi Sri
Published: November 2018

Penelitian ini bertujuan untuk mengetahui konsumsi pangan rumah tangga petani karet serta mengetahui faktor-faktor yang mempengaruhi  konsumsi pangan rumah tangga petani karet di Kecamatan Batin XXIV Kabupaten Batanghari. Penelitian ini dilaksanakan dari tanggal 25 November 2012 sampai dengan 25 Desember 2012. Data yang digunakan meliputi data primer dan data sekunder. Metode yang digunakan yaitu metode survey dengan wawancara secara langsung menggunakan metode recall 24 jam dan food frequency yang dilakukan dalam tiga kali perhitungan serta pengisian kuisioner yang telah dipersiapkan. Berdasarkan hasil penelitian diperoleh bahwa : (1) Bahan makanan pokok sumber energi yang paling sering dikonsumsi oleh responden adalah dari kelompok padi-padian yaitu beras dengan frekuensi 3 kali perhari, pangan nabati yang paling sering dikonsumsi adalah jenis kedele dalam bentuk tahu dan tempe dengan frekuensi 4-6 kali perminggu, pangan hewani yang sering dikonsumsi adalah dari jenis ikan asin/teri sebesar 50 persen responden dengan frekuensi makan 4-6 kali perminggu. Serta ikan sebesar 27,3 persen responden dengan frekuensi makan 2-3 kali permiggu. Rata-rata konsumsi energi dan protein rumah tangga petani karet di Kecamatan Batin XXIV Kabupaten Batanghari adalah 2.100,91 kkal/kapita/hari dan 47,53 gram/kapita/hari. (2) jumlah anggota rumah tangga dan penerimaan mempengaruhi konsumsi energi dan protein rumah tangga petani karet. Sedangkan pendidikan tidak mempengaruhi konsumsi energi dan protein rumah tangga petani karet di Kecamatan Batin XXIV Kabupaten Batanghari.   Kata Kunci : Kecukupan Konsumsi Pangan Energi Dan Protein
SISTEM PEMASARAN E-COMMERCE PRODUK PERTANIAN BERBASIS WEB CONTENT MANAJEMEN SYSTEM
Authors: Suratno Tri
Published: November 2018

Dalam era teknologi informasi sekarang ini, pemanfaatan aplikasi web tidak hanya sebagai media penyebar data dan informasi. Aplikasi web dapat digunakan dalam memasarkan hasil produk, yang dikenal dengan nama e-commerce atau online marketing. E-commerce merupakan  jual beli barang, jasa dan informasi melalui jaringan komputer internet atau sarana elektonik lainnya. Alur proses sistem e-commerce sama seperti penjualan dalam sebuah supermarket,yaitu mengambil keranjang belanja diawal masuk, kemudian memilih barang sesuai dengan keinginan, dan setelah barang diambil selanjutnya melakukan pembayaran dikasir.. Tujuan penelitian ini adalah melakukan perancangan  sistem pemasaran e-comerce produk pertanian berbasis web content manajemen sistem, yang dapat digunakan dalam memasarkan produk home industri yusra. Metode yang dilakukan dalam penelitian ini yaitu menggunakan pendekatan  waterfall life cycle model yang terdiri dari pengumpulan kebutuhan sistem, perancangan, pembangunan, pengujian, penerapan, serta operasi dan pemeliharaan. Hasil dari penelitian ini adalah sebuah aplikasi web yang dapat digunakan secara online untuk memasarkan hasil produk home industri yusra.   Kata Kunci : E-commerce, web, informasi, content manajemen system,
PARTISIPASI ANGGOTA PADA KEGIATAN KELOMPOK TANI KELAS LANJUT KHUSUS PADA TANAMAN KELAPA SAWIT
Authors: Purnomo Edi , Denmar Denny , Aprolita .
Published: November 2018

Penelitian ini merupakan penelitian survey yang bertujuan untuk mengetahui suatu kegiatan kelompok tani bagaimana cara mengembangkan kemampuan petani melalui peningkatan kelompok sehingga  meningkatkan taraf hidup dan perekonomian petani serta anggota kelompok tani. Petani dalam proses pembangunan pertanian adalah insan pembangunan yang berperan sebagai pelaku utama. Sebagai manusia pembangunan yang utama petani dengan kelompok taninya mempunyai potensi yang sangat besar untuk dikembangkan menuju usaha tani yang produktif dan menguntungkan. Namun demikian disadari bahwa saat ini belum semua petani menjadi anggota kelompok tani atau pun kalau sudah berkelompok, tingkat kemampuannya masih beragam. Kelompok tani adalah kumpulan petani yang tumbuh berdasarkan keakraban dan keserasian, serta kesamaan kepentingan dalam memanfaatkan sumber daya pertanian untuk bekerjasama meningkatkan produktivitas usaha tani dan kesejahteraan anggotanya yang dipimpin oleh seorang ketua yang disebut kontak tani. Jumlah anggota tiap kelompok minimum 10 orang dan maksimum disesuaikan dengan jenis usaha tani dan kondisi setempat. Pencapaian tujuan kelompok tani dapat terlihat jelas dari partisipasi anggota dalam melaksanakan kegiatan kelompok tani yang disusun berdasarkan rencana usaha kelompok yang meliputi pertemuan kelompok dengan PPL, pengadaan saprodi, penanaman dan pemeliharaan, panen dan pasca panen.  Dengan pentingnya keberadaan peran partisipasi dalam kelompok maka peningkatan partisipasi anggota dalam kelompok mutlak dilakukan yang mana akan meningkatan pula kemampuan kelompok dalam melaksanakan kegiatan kelompok yang telah disepakati bersama. Kelompok tani adalah merupakan suatu sasaran yang cukup strategis dalam pencapaian suatu tujuan dengan fungsi sebagai wadah dalam proses belajar mengajar, bekerja bersama dan wahana produksi.   Kata kunci : Partisipasi, Kelompok Tani kelas lanjut, Jenis Partisipasi dan factor yang berhubungan
PEMANFAATAN SISTEM INFORMASI DAN TEKNOLOGI INFORMASI UNTUK MENUNJANG E-AGRIBISNIS
Authors: Suratno Tri
Published: November 2018

Tulisan ini bertujuan untuk mengetahui pemanfaatan sistem informasi dan teknologi informasi dalam menunjang ecommerce atau dalam bidang pertanian disebut e-agribisnis. Penggunaan e-agribusiness dalam dunia pertanian digunakan untuk kegiatan pertanian yang memanfaatkan sistem informasi dan teknologi informasi. Untuk membuat aplikasi e-agribusiness dapat memanfaatkan aplikasi web yang open source, sehingga untuk pembuatan program e-agribusiness tidak membutuhkan biaya yang relatif besar, aplikasi web yang digunakan berupa sistem manajemen konten, seperti joomla, drupal, wordpress dan lain.lain.  Dalam sistem manajemen konten ini, pengguna dapat menambah, mengedit, mengelola, dan memasukan konten-konten yang ada seperti teks, grafis, video, dokumen, bahkan dapat melayout ulang web yang dibuat. Setelah membuat web menggunakan sistem manajemen konten, selanjutnya menentukan nama domain dan hosting. Domain adalah sebuah alamat, yang dapat diakses oleh pengunjung situs. Misalnya www.google.com, www.deptan.com domain berfungsi sebagai alamat dan sekaligus sebagai brand (merek) dari sebuah perusahaan, sehingga apabila nama domain mudah di ingat dan di kenal, akan mempengaruhi pengguna mengunjungi situs.  Hosting  berfungsi sebagai  tempat menyimpan semua data-data yang berhubungan dengan website. Hosting terhubung dengan internet selama 24 jam sehingga pengguna yang ingin melihat website dapat mengunjunginya kapan saja. Dalam menerapkan e-agribusiness diharapkan dapat menggunakan aplikasi web yang sudah ada seperti sistem manajemen konten, sehingga pengguna yang mengelola e-agribusiness dapat membangun e-agribusiness sendiri.   Kata Kunci : Sistem, teknologi, Informasi, e-agribusiness, e-commerce.
HUBUNGAN KOMUNIKASI INTERPERSONAL TENAGA PENDAMPING DENGAN PARTISIPASI PETANI DALAM PROGRAM AKSI DESA MANDIRI PANGAN (PROKSI DEMAPAN) DI KELURAHAN PALL MERAH KOTA JAMBI
Authors: Fitriyani . , Denmar Denny , Nurfathiyah Pera
Published: November 2018

Ketahanan pangan adalah kondisi terpenuhinya pangan bagi rumah tangga yang tercermin dari tersedianya pangan yang cukup, baik jumlah maupun mutunya, aman, merata dan terjangkau. Salah satu upaya mengatasi masalah kerawanan pangan dan kemiskinan adalah melalui Program Aksi Desa Mandiri Pangan. Penelitian ini bertujuan untuk mengetahui tingkatan pelaksanaan komunikasi interpersonal yang digunakan tenaga pendamping dalam Program Aksi Desa Mandiri Pangan di Kelurahan Pall Merah Kota Jambi serta untuk mengetahui hubungan antara komunikasi interpersonal tenaga pendamping dengan partisipasi petani dalam Program Aksi Desa Mandiri Pangan di Kelurahan Pall Merah Kota Jambi. Pemilihan lokasi dilakukan secara purposive dilatar belakangi karena Kelurahan Pall Merah telah mengikuti Program Aksi Desa Mandiri Pangan pada tahun 2010 hingga sekarang telah mencapai tahap kemandirian dan kondisi perkembangan dana bantuan sosial cukup tinggi di antara Kelurahan lainnya yang mengikuti program tersebut. Jenis data dalam penelitian ini meliputi data primer dan sekunder. Data dianalisis secara deskriptif melalui tabel distribusi frekuensi. Uji analisis yang digunakan adalah uji dengan metode Chi-Square (χ2). Dari hasil penelitian diperoleh bahwa : 1) Komunikasi interpersonal yang digunakan tenaga pendamping kategori tinggi sebesar 45%, sedang sebesar 35% dan rendah sebesar 20%. Hal ini menunjukan komunikasi interpersonal yang digunakan tenaga pendamping dalam program Aksi Desa Mandiri Pangan efektif. 2) Terdapat hubungan yang erat antara komunikasi interpersonal tenaga pendamping dengan partisipasi petani dalam Program Aksi Desa Mandiri Pangan di Kelurahan Pall Merah Kota Jambi.   Kata Kunci : Komunikasi Interpersonal, Partisipasi Petani, Ketahanan Pangan.