bluuebunny/crossref_metadata_2025 huggingface dataset:
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale
Authors: PIMENTA Larissa Salustiano Evangelista , MELLO Cláudia Berlim de , SOARES Diogo Cordeiro de Queiroz , DANTAS Anelisa Gollo , MELARAGNO Maria Isabel , KULIKOWSKI Leslie Domenici , KIM Chong Ae
Published: November 2019

Abstract The 22q11.2 Deletion Syndrome (22q11.2DS), the most common human chromosome microdeletion syndrome, is associated with a very heterogeneous neurocognitive phenotype. One of the main characteristics of the syndrome spectrum is the intellectual variability, which encompasses average performance and intellectual disability and discrepancies between Verbal Intelligence Quotient and Performance Verbal Intelligence Quotient, with greater impairment in nonverbal tasks. The present study aimed at investigating the intellectual performance aspects of a 21children and adolescents sample from Brazil who had been diagnosed with 22q11.2DS, based on the Wechsler Intelligence Scale for Children - 4th edition. The samples were reviewed considering the differences between indices. The results revealed an Full Scale Intelligence Quotient predominant in the borderline range (42 to 104) and a significant discrepancy between the indices of Verbal Comprehension and Perceptual Reasoning in 42% of the sample. With regard to the performance in the subtests alone, a better performance was found in Similarities, whereas block design, matrix reasoning, digit span and letter-number sequencing subtests were the most challenging. These findings indicate that a comprehensive assessment of intellectual performance aspects covering the different measures of the Wechsler Intelligence Scale may contribute to a broader understanding of the neurocognitive phenotype associated with 22q11.2DS.
Mapping self-report questionnaires for socio-emotional characteristics: What do they measure?
Authors: PRIMI Ricardo , SANTOS Daniel Domingues dos , HAUCK Nelson , FRUYT Filip De , JOHN Oliver Peter
Published: November 2019

Abstract Whereas the structure of individual differences in many social and emotional attributes is well understood in adults, much less work has been done in children and adolescents. The main goals of this research were to specify the major content domains that are assessed across multiple socioemotional instruments (self-esteem, grit, self-efficacy, strengths and difficulties, Big Five) in research in the United States and Europe, to test them in a less developed context with considerable educational challenges (Brazilian schools). We selected the five most promising instruments and studied their structure at the item level in a large sample of Brazilian school students (N = 3,023). The extracted factors to capture the major domains of child differences represented in these instruments closely resembled the Big Five personality dimensions. We discuss the contribution of our findings to the assessment of socio-emotional skills in education research, as well as limitations of the current study, and suggestions for future research.
Being a truck driver in Brazil: From implicit self-stereotypes to system justification
Authors: MESSIAS João Carlos , CAVIERES-HIGUERA Hector , SILVA Ramon Araújo , FACUNDO Gabriela Nogueira de Senna , LESSA Renata Thurler
Published: November 2019

Abstract Close to two million people currently work in Brazil's road transport sector, the country's leading logistical area. Most are self-employed individuals. The objective of this research project was to garner an understanding of the perceptions that Brazilian truck drivers hold regarding themselves. Eight experienced drivers were interviewed, starting from the question â"What is it like being a truck driver in Brazil?", and their responses were analyzed in accordance with social discourse studies. Five main categories – with specific subdivisions – were identified, relating to motivations to work in this area, contextual elements, and positive, group, and negative self-image. It is concluded that self-stereotypes play an important role in maintaining the situation of disadvantage and precarious working conditions that affect truck drivers.
School Improvement Trajectories in Chile: a case study
Authors: Rodríguez Luis Felipe de la Vega
Published: November 2019

Abstract: Progress in educational improvement research has generated consensus about the need to pay closer attention to the context within which it develops as well as to the multiple levels and participants involved in it. Within that analytic framework, a study was conducted to identify how the improvement trajectories experienced by schools can help understand their current scenario of strengths and weaknesses. Eight case studies were carried out in different types of Chilean schools, considering their socioeconomic and academic achievement characteristics. First, this study assessed the presence of educational improvement attributes in the schools. Following this, in-depth analyses of the trajectories of the four schools that attained the highest scores in the assessment were conducted. With the results obtained, an explanatory model was generated to describe the educational improvement trajectories of the schools that were analyzed. This model involves three stages (bring order; achieve organization, and improve teaching-learning), each of which includes one main process.
Política Educacional no Ceará: processos estratégicos
Authors: Vieira Sofia Lerche , Plank David Nathan , Vidal Eloisa Maia
Published: November 2019

Resumo: O artigo discute processos estratégicos à formulação e implementação da política educacional no Ceará no período 1995-2015, tendo por referencial as teorias da governança e da dependência da trajetória. O texto analisa aspectos relativos ao equilíbrio fiscal do estado, práticas meritocráticas de recrutamento e mecanismos de monitoramento associados à gestão por resultados. Nesse cenário, três processos estratégicos foram determinantes para criar condições propícias à melhoria da educação: a colaboração, a mobilização e a responsabilização. São apresentadas evidências de que tais processos, construídos historicamente na educação cearense, abriram caminho para a instituição de uma cultura institucional favorável à mudança, a exemplo da melhoria dos resultados obtidos pelo estado em processos de avaliação externa.
Resultados de Proyectos Socioeducativos en el Desarrollo Humano de los Jóvenes
Authors: Figueiredo Gustavo de Oliveira , Weihmüller Valentina Carranza , Orrillo Yansy Aurora Delgado
Published: November 2019

Resumen: El trabajo presenta y discute los resultados de una pesquisa participativa con 18 educadores sociales que desarrollan proyectos socioeducativos con jóvenes en 12 favelas de Rio de Janeiro. Por medio de cuestionarios, entrevistas individuales y grupos focales, en el marco de la Investigación-Acción-Participativa (IAP), este trabajo tiene por objetivo identificar y reflexionar sobre los efectos/resultados de los proyectos en el desarrollo humano de los jóvenes. Los resultados de la investigación demuestran que los educadores sociales perciben un efecto muy positivo de las intervenciones en la vida de los jóvenes, principalmente en indicadores a nivel personal, evidenciando aún limitaciones de los proyectos a nivel colectivo.
Estoque e perda de necromassa da vegetação lenhosa em um gradiente fitofisionômico na transição Amazônia-Cerrado
Authors: Carneiro Karla Monique Silva , Reis Simone Matias , Morandi Paulo Sérgio , Elias Fernando , Oliveira Edmar Almeida de , Marimon-Junior Bem Hur , Marimon Beatriz Schwantes
Published: November 2019

Resumo A necromassa é um importante componente da decomposição e ciclagem de nutrientes nos ecossistemas naturais. Nosso objetivo foi avaliar o estoque e perda de necromassa da comunidade e das espécies em um gradiente fitofisionômico de cerrado típico, cerradão e floresta estacional semidecidual, na transição Amazônia-Cerrado. Calculamos, para cada fitofisionomia, o estoque de necromassa, por meio dos diâmetros dos indivíduos mortos em pé em 2005, 2008, 2011 e 2013. Também calculamos a perda de necromassa da comunidade e das espécies por meio dos diâmetros dos indivíduos que permaneceram mortos em pé entre, pelo menos, dois censos (2002-2005; 2005-2008; 2008-2011 ou 2011-2013). O cerrado típico apresentou estoque e perda de necromassa significativamente inferior ao cerradão e à floresta estacional. Ao nível de espécie, a taxa de decomposição de necromassa não apresentou correlação com a densidade da madeira. Maiores estoque e perda de necromassa na floresta estacional em relação ao cerrado típico podem estar relacionados ao maior porte dos indivíduos, que pode propiciar maior cobertura do dossel e microclima mais favorável à ação de organismos decompositores. Dessa forma, características intrínsecas de cada fitofisionomia podem estar relacionadas diretamente ao estoque e perda de necromassa em formações savânicas e florestais da transição Amazônia-Cerrado.
Contribuições para a flora de samambaias da Serra dos Carajás, Pará, Brasil
Authors: Lima Lucas Vieira , Souza Filipe Soares de , Viveros Raquel Stauffer , Arruda André Jardim , Salino Alexandre
Published: November 2019

Resumo Este estudo trata os táxons das famílias Athyriaceae, Lomariopsidaceae, Metaxyaceae e Saccolomataceae (Polypodiopsida) encontrados nas formações de Floresta Ombrófila Densa circunvizinhas às formações de canga da Serra dos Carajás, estado do Pará, e conta com descrições, imagens, distribuição e comentários. Na área de estudo foram registradas oito espécies distribuídas em cinco gêneros.
Diagnóstico do conhecimento da biodiversidade de plantas vasculares nas unidades de conservação do estado de São Paulo
Authors: Colli-Silva Matheus , Ivanauskas Natália Macedo , Souza Flaviana Maluf
Published: November 2019

Resumo Com base em dados publicados sobre a ocorrência de espécies de plantas vasculares no estado de São Paulo, avaliamos a performance das unidades de conservação (UCs) na proteção dessas espécies, considerando especialmente aquelas endêmicas do estado e as ameaçadas de extinção. Das 648 espécies de samambaias e licófitas no estado, 71% ocorrem em UCs, 10 são endêmicas de São Paulo e 30 estão ameaçadas de extinção. Pouco menos da metade das espécies de samambaias e licófitas ameaçadas não foram registradas em UCs, e três são endêmicas do estado. Para as plantas com semente, das 8.521 espécies registradas, 48% ocorrem em UCs, 361 são endêmicas do estado e 676 estão ameaçadas de extinção. Entretanto, 65% das espécies ameaçadas estão desprotegidas, e 51 destas são endêmicas do estado, a maioria nativa da Mata Atlântica. Muitas UCs ainda possuem grande lacuna de conhecimento sobre a flora, de esforço de coleta de material botânico e de registro em herbários, com destaque para as Reservas Particulares do Patrimônio Natural (RPPNs). Nossos dados reforçam a necessidade de ampliação de coletas botânicas em UCs, bem como a criação de novas áreas no estado, a fim de proteger espécies ameaçadas e endêmicas da flora paulista.
Papilionoideae (Leguminosae) no Chaco brasileiro
Authors: Sinani Thomaz Ricardo Favreto , Lima Laura Cristina Pires , Alves Flávio Macedo , Matos-Alves Fábio , Sciamarelli Alan , Sartori Ângela Lúcia Bagnatori
Published: November 2019

Resumo O Chaco é maior domínio de florestas contínuas da América do Sul e agrega distintas famílias botânicas com destaque à Leguminosae. A elevada riqueza e diversidade de membros de Leguminosae, sobretudo de Papilionoideae, aliada à distribuição de determinados gêneros comuns às florestas secas tem motivado a investigação deste interessante grupo de plantas nas formações chaquenhas do Brasil. Este estudo florístico-taxonômico fornece chave de identificação, descrições morfológicas, ilustrações, comentários taxonômicos e ambientes preferenciais das espécies de Papilionoideae ocorrentes no Chaco do Brasil. Confirmamos a ocorrência de 45 espécies, distribuídas em 21 gêneros. Os gêneros com maior número de espécies são Aeschynomene (10), Galactia (4), Indigofera (4), Stylosanthes (4) e Desmodium (3). Os demais encontram-se representados por duas ou uma espécie: Arachis (2), Centrosema (2), Macroptilium (2), Rhynchosia (2), Amburana (1), Ancistrotropis (1), Camptosema (1), Crotalaria (1), Discolobium (1), Dolichopsis (1), Geoffroea (1), Machaerium (1) e Muellera (1), Sesbania (1), Tephrosia (1) e Zornia (1). Espécies dos gêneros Muellera, Dolichopsis e Geoffroea são exclusivas de áreas secas da América do Sul. Aeschynomene magna é registrada pela primeira vez para o Brasil, e considerada endêmica do Chaco. Stylosanthes maracajuensis é o primeiro registro para o Chaco.
Effects of Class II division 1 malocclusion treatment with three types of fixed functional appliances
Authors: Brito Deborah Brindeiro de Araújo , Henriques José Fernando Castanha , Fiedler Camilla Foncatti , Janson Guilherme
Published: November 2019

ABSTRACT Objective: This study aimed at comparing the dentoskeletal changes in patients with Class II division 1 malocclusion, treated with three types of fixed functional appliances. Methods: A sample comprising 95 patients with the same malocclusion, retrospectively selected, and divided into four groups, was used: G1 consisted of 25 patients (mean age 12.77 ± 1.24 years) treated with Jasper Jumper appliance; G2, with 25 patients (mean age 12.58 ± 1.65 years) treated with the Herbst appliance; G3, with 23 patients (mean age 12.37 ± 1.72 years) treated with the Mandibular Protraction Appliance (MPA); and a Control Group (CG) comprised of 22 untreated subjects (mean age 12.66 ± 1.12 years). Intergroup comparison was performed with ANOVA, followed by Tukey test. Results: The Jasper Jumper and the Herbst group showed significantly greater maxillary anterior displacement restriction. The Jasper Jumper demonstrated significantly greater increase in the mandibular plane angle, as compared to the control group. The MPA group demonstrated significantly greater palatal inclination of the maxillary incisors. Vertical development of the maxillary molars was significantly greater in the Herbst group. Conclusions: Despite some intergroup differences in the amount of dentoskeletal changes, the appliances were effective in correcting the main features of Class II malocclusions.
Evaluation of palate area before and after rapid maxillary expansion, using cone-beam computed tomography
Authors: Bruder Carolina , Ortolani Cristina Lucia Feijó , Lima Tatiana Araújo de , Artese Flavia , Faltin Junior Kurt
Published: November 2019

ABSTRACT Objective: The aim of this study was to estimate the changes in the palate area after rapid maxillary expansion (RME) with the Hyrax expander in growing subjects, using cone beam computed tomography (CBCT). Methods: Fourteen patients (9 girls and 5 boys; mean age = 11.7 ± 2.4 years) who required RME as part of their orthodontic treatment were included in this study. CBCT records had been taken before RME treatment (T0), at the end of active expansion (T1) and after a 6-month retention period (T2). The CBCT scans were manipulated with Dolphin Imaging® version 11.7 Premium software, in which landmarks were positioned and measured in relation to sagittal, coronal and axial planes, to verify the palate surface area. In addition, linear measurements of the palatal depth and width were assessed. These measurements were compared by using analysis of variance (ANOVA) for repeated measures. A p-value smaller than 0.05 was considered statistically significant. Results: The palatal surface area and width significantly increased from T0 to T1, respectively by 9.27% and 9.71%, and both decreased in a non-significant manner from T1 to T2. The palatal depth had non-significant differences at T0, T1 and T2. Conclusions: RME promotes a significant gain in the surface area of the palate and an increase in intermolar width. The Hyrax appliance was effective for the treatment of maxillary atresia in growing patients. There was no vertical alteration of the palate. After a 6-month retention period, the maxilla transverse dimension and the surface area of the palate remained stable.
Failure rates of miniscrews inserted in the maxillary tuberosity
Authors: Azeem Muhammad , Haq Arfan Ul , Awaisi Zubair Hassan , Saleem Muhammad Mudassar , Tahir Muhammad Waheed , Liaquat Ahmad
Published: November 2019

ABSTRACT Introduction: Anchorage conservation in orthodontics has always been a challenge. Objective: The aim of this current study was to find out the failure rate of miniscrews inserted in the maxillary tuberosity (MT) region. Methods: This pilot study consisted of 40 patients (23 female, 17 male; mean age = 20.1±8.9 years) that had received 60 MT miniscrews for orthodontic treatment. Clinical notes and pictures were used to find out the primary outcome of miniscrew failure. Independent failure factors were also investigated. Logistic regression analysis was done for predictor’s relation with MT miniscrews failure. Results: There was no significant correlation in failure rate according to various predictor variables, except for miniscrews installed by lesser experienced operators, which showed significantly more failure. The odds ratio for miniscrew failure placed by inexperienced operators was 4.16. Conclusion: A 26.3% failure rate of mini-implants inserted in the MT region was observed.
Sobrecarga térmica em áreas rurais: a influência da intensidade do trabalho
Authors: Roscani Rodrigo Cauduro , Maia Paulo Alves , Monteiro Maria Inês
Published: November 2019

Resumo Introdução: a legislação brasileira determina que se monitore o Índice de Bulbo Úmido Termômetro de Globo (IBUTG) nos ambientes de trabalho em que o calor possa representar risco à saúde dos trabalhadores. Porém, esse monitoramento e a adoção de medidas preventivas não são comumente observados. Objetivo: identificar e mapear a influência da intensidade do trabalho na extrapolação potencial de limites de sobrecarga térmica para trabalhadores em atividade a céu aberto em áreas rurais do Nordeste do Brasil. Métodos: com base na Norma Regulamentadora nº 15 e em dados do Instituto Nacional de Meteorologia, o software Sobrecarga Térmica foi utilizado para estimar os índices de IBUTG na região, no período de 1º de setembro de 2016 a 31 de agosto de 2017. Resultados: dos 132 pontos geográficos investigados, a extrapolação dos limites de sobrecarga térmica foi identificada em 48% dos trabalhos pesados e em 14% dos trabalhos moderados, indicando a necessidade de paradas para descanso em mais de 50% do tempo analisado. Discussão: a diminuição da intensidade do trabalho resulta em redução expressiva da sobrecarga térmica. Nas localidades historicamente reconhecidas pelo alto risco de exposição ao calor, deveria ser adotada, como medida efetiva de prevenção, a restrição ao estímulo de atividades extenuantes, sobretudo as promovidas pela remuneração atrelada à produtividade.
Visibilidad e impacto altmétrico de los investigadores de la Universidad de Antioquia: metodología aplicable a universidades
Authors: URIBE-TIRADO Alejandro , OCHOA-GUTIÉRREZ Jaider , RUIZ-NUÑEZ Kelis , FAJARDO-BERMÚDEZ Marcela
Published: November 2019

Resumen Este trabajo es resultado de uno de los componentes de una investigación macro que busca crear un Modelo para identifi car el grado de vinculación de una universidad con su entorno, en este caso, aplicado a la Universidad de Antioquia (Medellín-Colombia). Este componente se refi ere a la visibilidad e impacto de los investigadores desde la perspectiva y datos que ofrecen las altmetrics.Para ello, se analizan los datos altmétricos de 1.032 investigadores de seis áreas del conocimiento, considerando diferentes plataformas académicas, profesionales y sociales, además de una plataforma integradora de indicadores altmétricos. Aunque se realiza esta medición para investigadores de la Universidad de Antioquia, la metodología general para la captura e interpretación de datos puede aplicarse a otras universidades que comparten características de investigación y de comunicación científi ca y que, a partir de las altmetrics, desean identifi car la visibilidad e impacto de sus investigadores y la vinculación misma de lainstitución con su entorno, para complementar, de esta manera, las mediciones bibliométricas tradicionales u otras mediciones del entorno de la universidad, como lo considera, por ejemplo, el Manual de Valencia.
In vitro evaluation of the association of chitosan and cashew nut shell liquid as additives for ruminants
Authors: PEREIRA Daniele Cristina , GOES Rafael Henrique de Tonissi e Buschinelli de , MARTINEZ Antônio Campanha , GANDRA Jefferson Rodrigues , PRESENDO Eduardo , SANTOS Mariana Viegas dos , OLIVEIRA Raquel Tenório , SILVA Nayara Gonçalves da , RIBEIRO Max Gimenez , ALVEZ Jefferson Leonardo Rocha
Published: November 2019

ABSTRACT This study evaluated the in vitro digestibility of nutrients from different diets added with chitosan (Q), technic cashew nut shell liquid (LCC) and the association of Q and LCC. The treatments used consisted of 4 diets (forage: concentrate ratio of 100: 0, 50:50, 40:60 and 20:80) associated with 4 additives (control, chitosan, LCC and the association of Q + LCC), totaling 16 treatments, in a 4x4 factorial randomized block design. The dosages used were: Control (without additives), LCC (600mg/kg DM), Chitosan (900mg/kg DM), and LCCQ (600mg/kg LCC DM + 900mg/kg Chitosan DM). In the laboratory, samples were analyzed for IVDMD, IVNDFD, IVCPD, pH and RAN (ruminal ammonia nitrogen). For pH and RAN analyses, samples were taken at 0, 2, 4, 6 and 8 hours after incubation. The results showed higher digestibility of DM, NDF and CP for diets with chitosan and technic cashew nut shell liquid alone and higher pH and RAN values in the diets containing the two additives. The association of additives brings better results for animal nutrition and increases ruminant productivity.
Determining anthelmintic residues in goat milk in Brazil
Authors: PORTO FILHO José Matias , COSTA Roberto Germano , ARAÚJO Adélia Cristina Pessoa , ALBUQUERQUE JÚNIOR Eden Cavalcanti , CUNHA Adriano Nunes , CRUZ George Rodrigo Beltrão da
Published: November 2019

SUMMARY Anthelmintics are used to combat nematodes. The misuse of anthelmintics can raise the cost of milk production. The objective of this research was to determine the presence of anthelmintics in goat milk. Twenty goats were used, divided into four groups of five animals: I- animals treated with an ivermectin-based anthelmintic; II- animals treated with moxidectin; III- animals treated with levamisole hydrochloride; and IV: animals treated with albendazole. Milk samples were collected individually: before, and 1, 2, 3, 15 and 21 days after administration of the anthelmintics. Determination of anthelmintic residues was performed by liquid chromatography-mass spectrometry (LC-MS). According to the results, there was an exponential effect (P<0.05) for ivermectin and moxidectin. Moxidectin was the anthelmintic that left a residue in the milk for the longest time, up to 21 days. However, with all the anthelmintics researched, residues were below the maximum limit recommended by the inspecting agencies.
Physiological and N2-fixation-related traits for tolerance to drought in soybean progenies
Authors: Cerezini Paula , Kuwano Biana Harumi , Neiverth Walkyria , Grunvald Anna Karolina , Pípolo Antonio Eduardo , Hungria Mariangela , Nogueira Marco Antonio
Published: November 2019

Abstract: The objective of this work was to evaluate six soybean (Glycine max) genotypes for physiological traits and biological nitrogen fixation in drought conditions, and their capacity for recovery after rewetting, based on yield components. The genotypes evaluated in a greenhouse were the following: 'BRS 317', susceptible to drought; R01-581F and R02-1325, which show biological nitrogen fixation tolerant to drought; and the BRB14-207525, BRB14-207526, BRB14-207527 breed lines resulting from crossings between commercial genotypes and PI 471938, which shows a slow-wilting phenotype under drought. Drought conditions were applied to the genotypes at the full-flowering stage (R2) for ten days, whereas control plants were kept well-watered. Photosynthetic rate and gas exchanges under drought were more stable in the BRB14-207526 genotype. Root biomass increased 3.5 times in R02-1325 as an adaptive response to drought. In addition, leaf ureides - a trait related to biological nitrogen fixation in plants tolerant to drought - remained stable in genotypes R02-1325 and R01-581F exposed to drought, but decreased in BRB14-207527. Genotypes BRB14-207526, BRB14-207527, and R02-1325 show more favorable physiological performances and a lower accumulation of ureides under drought, besides a higher grain yield after rehydration. The BRB14-207526 and BRB14-207527 progenies show drought-tolerance traits from PI 471938, whereas R02-1325 is a promising source of tolerance to drought for soybean breeding.
Efficient inoculation of diazotrophic bacteria into sugarcane by the drip irrigation system
Authors: Simões Welson Lima , Oliveira Anderson Ramos de , Souza Moises Alves de , Reis Verônica Massena , Ivan Fernandes-Júnior Paulo
Published: November 2019

Abstract: The objective of this work was to assess the efficiency of the inoculation of a diazotrophic bacterial consortium by the drip irrigation system into sugarcane (Saccharum spp.), in the Brazilian semiarid region. The evaluated treatments were: standard inoculation by submersion; one or two inoculations by drip irrigation; nitrogen (urea) applied by fertigation; and negative controls, without inoculation or nitrogen fertilization. Leaf gas exchanges and plant growth and yield were assessed. Inoculation by irrigation is efficient for all variables, and double inoculation by the drip irrigation system stands out, increasing stem yield in 16% when compared with the negative control, without differing from the treatment with nitrogen fertilizer.
Growth curves of meat-producing mammals by von Bertalanffy’s model
Authors: Fernandes Felipe Augusto , Fernandes Tales Jesus , Pereira Adriele Aparecida , Meirelles Sarah Laguna Conceição , Costa Adriano Carvalho
Published: November 2019

Abstract: The objective of this work was to evaluate how the parameterization and the application of different allometric values affect the obtention of the most adequate fit of von Bertalanffy’s model, in the description of the growth curve of meat-producing mammals (bovine, pigs, rabbits, and sheep). Among the nonlinear models, von Bertalanffy’s has been very often applied in several areas, with different parameterizations. This model has been commonly used with an allometric value of m = 2/3; however, for mammals, it is believed that this value can be m = 3/4. The analyzed data referring to the mass of meat-producing mammals according to their age were obtained from research institutions and from the literature. The results showed that von Bertalanffy’s model, with the allometric value of m = 3/4 and the used parameterization, provided better adjustments to quality evaluators. Besides, the model softened the overestimation of parameter a, giving a direct interpretation of parameter b, with the lowest values for curvature measurements, mainly for the parametric ones, and provided more reliable adjustments. Von Bertalanffy’s model can be used in the description of the growth curves of meat-producing mammals.
Starch digestibility and sensory acceptance of gluten free foods prepared with tannin sorghum flour
Authors: Soares Raquel Rainier Alves , Vasconcelos Christiane Mileib , Oliveira Mariane Verônica de , Minim Valéria Paula Rodrigues , Queiroz Valéria Aparecida Vieira , Barros Frederico
Published: November 2019

Abstract: The objective of this work was to develop gluten-free cookies and savory fried pies using tannin-rich sorghum (Sorghum bicolor) flour, to evaluate their in vitro starch digestibility, and to verify how knowledge of sorghum benefits may contribute to the sensory acceptability of both products. The contents of rapidly digestible starch, slowly digestible starch, and resistant starch were determined. Sensory acceptance was evaluated in two sessions: one without information on sorghum benefits to human health; and another where this information was presented. The resistant starch and slowly digestible starch contents of the cookies (5.07 and 16.22%, respectively) were about twice those of the savory fried pies (2.54 and 8.89%, respectively), whereas the opposite was observed for the rapidly digestible starch contents (9.89 and 19.65%, respectively). The cookies and savory fried pies were sensorially accepted, with a significant increase in the means of the sensory scores after the information on sorghum benefits was disclosed. Therefore, gluten-free cookies and savory fried pies prepared with tannin sorghum flour have a great commercial potential, shown by the good sensory acceptance and by the slowly digestible starch and resistant starch contents of these products.
Nonlinear numerical analysis of composite slabs with steel decking
Authors: SILVA A. R. , SILVA P. B.
Published: November 2019

Abstract The composite slabs behavior is governed by longitudinal shear at the interface between the steel deck and concrete, which is developed in slabs under simple bending. The m-k method and the partial connection method, that are used in the evaluation of shear strength at the steel-concrete interface of composite slabs, are based on expensive and long-term experimental tests. The main objective of this work is to implement a finite element model for nonlinear numerical analysis of concrete slabs with steel decking. For this, flat shell elements are implemented, considering Reissner-Mindlin and Kirchoff plate theories, bar elements, considering the beam theory of Tymoshenko, and interface elements. In the numerical analyzes presented in the present work, the steel deck and the concrete slab, of thickness given by the total height of the slab less the height of the steel deck, are modeled with flat shell elements. The concrete rib is modeled with bar elements. The contact between steel deck and concrete is modeled through interface elements. The geometric and material nonlinearities are considered in the numerical analysis. The analyzed examples validate the numerical model suggested in this work, presenting the advantage of using a two-dimensional discretization of the problem while in comparative numerical models are uses a three-dimensional discretization of the concrete slab.
Experimental study of reinforced masonry beams
Authors: CAMACHO J. S. , CONTADINI L. F. , PARSEKIAN G. A.
Published: November 2019

Abstract An experimental program on reinforced concrete masonry beams was conducted aiming to better understand the behavior of reinforced masonry beams. The beams were designed to fail in flexure, assessing cracking patterns, maximum displacement, ultimate bending moment, and maximum flexural and axial compression strain. The experimental program included 12 reinforced masonry beam tested under flexure and built with bond-beam and hollow concrete blocks. Also, two type of prism were built and tested; one type stacked into the block greater dimension allowing testing with compression in the same direction as in the beams; and the second type as standard grouted prisms. Results indicate an average masonry compression strength parallel to bed joint 25% lower than the masonry compression strength in the other direction (perpendicular to bed joints). There was a significant increase on the beam stiffness due to the construction of one more block course. The model used to calculate the ultimate bending moment led to values close to the experimental result (difference of about 15%). Finally, the ultimate average shortening strain of masonry at axial compression was 50% lower than at flexural compression.
Structural models for analysis of reinforced concrete frame buildings with masonry infills
Authors: ALVA G. M. S. , MONTANDON G. A.
Published: November 2019

Abstract The behavior of single-storey, single-bay reinforced concrete infilled frame with masonry panel subjected to static horizontal load was studied using two structural models: i) equivalent strut model (ESM) and ii) model with two-dimensional finite elements for state stress plane (MEF). In the first model, an equivalent diagonal strut replaces masonry. The axial stiffness of this element is defined by evaluation of the equivalent diagonal width. In the second model, the infilled frame is modeling by two-dimensional finite elements, requiring the simulation of the sliding and separation between the wall surfaces and the reinforced concrete frame. Although equivalent strut models are more attractive for design, the formulas found in the literature to determine equivalent strut width provide very different values. In addition, most of these formulas ignore some parameters that may be important, such as beam flexural stiffness. For this reason, several numerical analysis were be carried out. The models simulated usual geometric and mechanical characteristics observed in reinforced concrete buildings. The results of the two-dimensional finite element modeling (by software ANSYS) were used as reference for the evaluation of the results provided by the equivalent strut model. The comparison of results allowed the assessment of the analytical expressions for evaluation of the equivalent diagonal width. Based on this assessment, a new expression is proposed for buildings with similar characteristics as analyzed in this paper. The results of numerical simulations with MEF models also allowed for an evaluation of stresses and the probable cracking pattern in infill walls.
Reliability of reinforced concrete beams designed in accordance with Brazilian code NBR-6118:2014
Authors: SCHERER M. , MORSCH I. B. , REAL M. V.
Published: November 2019

Abstract This paper aims to evaluate the reliability indexes of reinforced concrete beams designed in accordance with brazilian code NBR-6118:2014 in relation to the ultimate limit state of flexure. The main statistics of the resistance model are obtained through Monte Carlo simulation using ANSYS software and its probabilistic design tool. The reliability indexes are evaluated by FORM, being performed a parametric study in order to assess the influence of the main design variables on the safety level reached. It can be noticed that the reliability indexes are shown unsatisfactory in the combinations which the live loads are predominant.
About the use of semi-continuity in simply supported composite steel and concrete beams, to remove fireproof coatings for standard-fire resistance requirement of less than 30 minutes
Authors: ROMAGNOLI L. C. , SILVA V. P.
Published: November 2019

Abstract Previous studies of the behavior under fire conditions of composite steel and concrete beams, not subjected to local buckling (compact steel profile), showed that it’s not possible to justify, by design code methods, the absence of fire coating for 30 minutes standard-fire resistance requirement, even when considering the support rotational stiffness provided by the upper longitudinal slab reinforcement (semi-continuity). The purpose of this work is to verify the viability of this proposal for lower standard-fire resistance time, which, although rare, may occur with the use of the equivalent time method.
Contribution to hierarchical modeling in tunnel design practice
Authors: DZIALOSZYNSKI B. S. , STUCCHI F. R.
Published: November 2019

Abstract This work presents a comparative analysis between two model hierarchies commonly applied in tunnel structural design: continuum ground models and bedded-beam models. Firstly, the main characteristics of each model and the interfaces between them are discussed. Based on those evaluations a simple procedure is proposed for determining the bedded-beam model imposed loads which lead to results compatible to those of a given continuum model. Said procedure is then explored to estimate simplified compatibilization loads for basic and illustrative cases, where a reasonable compatibilization was achieved for a relatively simple applied load.
ENAT Karacabey endüstriyel ağaçlandırma yatırımında hasılat ve iç karlılık analizi
Authors: ERKAN Neşat , OK Kenan , PARLAK Salih
Published: November 2019

Ülkemizde orman endüstrisinin ihtiyaç duyduğu odun ham maddesinin karşılanması konusu, uzun yıllardır gündemdeki önemini korumaktadır. Özellikle özel sektör tarafından yapılacak endüstriyel ağaçlandırma yatırımlarında, girişimin ekonomik sonuçlarının ne olacağı ve kurulan plantasyonların hangi idare süresiyle işletilmesi gerektiği konularının, bilimsel çalışmalarla ortaya konması gerekmiştir. Bu çalışmada, Endüstriyel Ağaç Tarımı Sanayi ve Ticaret A. Ş. (ENAT) tarafından Bursa-Karacabey’de Sahilçamı ile yapılmış 493 ha büyüklüğündeki ağaçlandırma sahası örnek alınarak değerlendirilmiştir. Çalışma, ağaçlandırma alanının değişik bölgelerinden alınan 15 adet deneme sahasındaki tek ağaca dayalı gövde analizleri ve alan bazında yapılan hasılat ölçmeleri temel alınarak yapılmıştır. Ekonomik analizler için İç Karlılık Oranı Kriteri kullanılmıştır. Elde edilen sonuçlar, Karacabey Sahilçamı ağaçlandırma alanının beşli sınıflamaya göre I. ve II. bonitet alanlarından oluştuğunu, çoğunluğu 12 yaşında olan sahada bu yaşta ortalama artımın 20 m3/yıl a kadar çıkabildiğini göstermiştir. Yapılan iç karlılık analiz sonuçları, değişik arazi edinme ve kullanım stratejilerine göre değişmekle birlikte, yatırım sahasında hesaplanan iç karlılık oranlarının %12,263’e kadar ulaştığını göstermektedir. Özellikle kullanılma olasılığı en yüksek strateji olan tahsisli araziler Sahilçamı ile ağaçlandırma yapılması durumunda iç karlılık oranının 16 yıl idare süresi için %11,183’e kadar yükseldiği gözlenmiştir. Diğer önemli bir bulgu ise, analizi yapılan 6 değişik stratejiden 5’i için, iç karlılık oranına göre idare süresinin 15 ve 16 yıl olmasıdır.
Changes of exosomal matrix metalloproteinases level in colorectal cancer associated with sex and metabolic disturbance
Authors: Yunusova N. V. , Zambalova E. A. , Patysheva M. R. , Dimcha A. A. , Cheremisina O. V. , Afanas’ev S. G. , Kondakova I. V.
Published: November 2019

The objective is to evaluate the contents of matrix metalloproteinases (MMP) MMP9, MMP2, as well as their inducer EMMPRIN in circulating exosomes of patients with colorectal cancer in relation with clinical and morphological parameters, as well as with the presence of metabolic syndrome to search for promising exosomal markers associated with invasion, metastasis and metabolic disorders.

Materials and methods. The study included 40 patients with colorectal cancer (T2–4N0–2M0–1) and 10 control patients. Exosomes of blood plasma were isolated by ultrafiltration with ultracentrifugation. The level of MMP9, MMP2 and their inducer EMMPRIN in exosomes was evaluated by flow cytometry.

Results and conclusion. The level of MMP9‑positive exosomes was significantly higher in patients with colorectal cancer compared with patients with colorectal polyps. The proportion of MMP9‑negative and triple positive MMP9 + / MMP2+ / EMMPRIN+ exosomes, on the contrary, was higher in patients with polyps compared with patients with colorectal cancer. Mixed subpopulation of MMP9+ / MMP2– / EMMPRIN-exosomes prevailed both in patients with colorectal cancer and in control patients. There were no significant differences in the subpopulations of MMP and EMMPRIN in the exosomes of colorectal cancer patients depending on the age, stage, grade and localization. Gender differences in the occurrence of a triple-positive exosome subpopulation in colorectal cancer patients have been revealed. No relationship was found between the expression of MMP and EMMPRIN in exosomes and the presence of the metabolic syndrome, anthropometric parameters, the level of total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol. However, the relationships between MMP9+ / MMP2– / EMMPRIN–, MMP9+ / MMP2– / EMMPRIN– and the level of triglycerides and glucose in blood serum were revealed. Further studies are needed to study the characteristics of exosomes associated with metabolic disorders and the possibility of their use as diagnostic, prognostic, or predictor biomarkers.
The level of some blood serum inflammatory factors in depending on the morphological features of the primary tumor of of cervical cancer
Authors: Kayukova E. V. , Belokrinitskaya T. E. , Sholokhov L. F. , Tereshkov P. P.
Published: November 2019

Background.Tumors influence on various vital processes in organism leading to cachexia, immunosuppression, anemia, changes in humoral regulation etc. Inflammation is one of the well-known etiological factors of carcinogenesis, including for cervical cancer, so we suggest that some blood serum inflammatory factors in patients with cervical cancer influence are associated with the level of tumor progression.

The objectiveof our study was to analyze the level of some hematological markers of inflammation in the blood serum of patients with cervical cancer in dependence on the histological characteristics of the primary tumors.

Materials and methods.In the study we analyzed the blood serum of patients with invasive cervical cancer I–IV stage (4 patients with verrucous cancer and 26 – with cervical cancer among them 10 – of G1 stage, 6 – of G2 stage, 10 – G3 stage) using flow cytometry. We studied the value of myoglobin, calprotectin, lipocalin, matrix metalloperoxidase 2, matrix metalloperoxidase 9, osteopontin, myeloperoxidase, serum amyloid A, protein 4, insulin-like growth factor-binding protein 4, cell-cell adhesion molecule 1, vascular cell adhesion molecule, cystatin С.

Results.We revealed the changes of some serum markers of inflammation in patients with G3 and verrocous cervical cancer.

Conclusion.The obtained dates demonstrate that further study of blood inflammatory markers as an additional differential and prognostic criteria in patients with cervical cancer should be considered as reasonable.
Differences in the profile of cytokine expression induced by implantation of oncogenic and non-oncogenic millipore filters
Authors: Rybalkina E. Yu. , Susova O. Yu. , Moizhess T. G.
Published: November 2019

Background. Clarification of the mechanisms of carcinogenesis induced by foreign bodies is one of the urgent problems of modern oncology. This is due to the fact that there is a relationship between the processes of inflammation and carcinogenesis. Today, there is no doubt the fact that cytokines and signal molecules in the focus of inflammation (products of inflammation) can contribute to the initiation of carcinogenesis, as well as stimulate tumor progression. In the case of carcinogenesis induced by foreign bodies, the key issue is understanding the differences in the body’s response to the implantation of foreign bodies that can cause tumor formation and do not have this ability. One of the phenomena of this type of carcinogenesis is the occurrence of sarcoma after the subcutaneous implantation in mice of hydrophilic millipore filters with a pore diameter not exceeding 0.1 μm and the inability to induce tumors of one’s with a pore diameter greater than or equal to 0.22 μm.

The objective of our work was to study the differences between oncogenic and non-oncogenic filters at the molecular level.

Materials and methods. Reverse transcription polymerase chain reaction method was used to study the expression of a number of cytokines that are products of macrophage cells that live on the surface of implanted filters and in the surrounding capsule. Filters with pore diameters of 0.025 μm (carcinogenic) and 0.45 μm (non-carcinogenic) were compared in 8, 35 days and 5.5 months after implantation.

Results and conclusion. After 8 days we observed significant (p <0.01) excess of expression of two cytokines interleukin 1β (IL-1β) by cells around oncogenic filters (with pore of 0.025 μm) compared to non-oncogenic one’s (with pore of 0.45 μm) After 35 days, significant (p <0.01) excess of expression of IL-1β, Tnf-α, iNOS (induced nitric oxide synthase), and IL-6 by cells around the oncogenic filters (0.025 μm) compared to non-oncogenic one’s (0.45 μm) was observed. There was no quantitative difference in the expression of Nf-κB1 and Nf-κB2 (nuclear factor κ-B1, κ-B2), Tgf-β (transforming growth factor β), IL-10. After 5.5 months the expression of IL-1β by cells on oncogenic filters was still significant; for Tnf-α, iNOS, IL-6 and IL-10 there was no practically difference in expression. For Nf-κB1 and Nf-κB2, Tgf-β and COX-2 (cyclooxygenase 2) the difference was significant, cells on non-oncogenic filters are expressed more then on oncogenic one’s.
Modern approaches for the screening of epigenetically active xenobiotics
Authors: Maksimova V. P. , Bugaeva P. E. , Zhidkova E. M. , Usalka O. G. , Lesovaya E. A. , Belitsky G. A. , Yakubovskaya M. G. , Kirsanov K. I.
Published: November 2019

Objective. Review of the modern methodological approaches for testing and studying the epigenetic activity of xenobiotics.

Materials and methods. In preparing the review, we used information databases of biomedical literature SciVerse Scopus (538), PubMed (746), Web of Science (625), RSCI (45). To obtain full-text documents, electronic resources of PubMed Central (PMC), Research Gate, RSCI, CyberLeninka were used. In the text of the review, 87 modern publications (2010–2019) were cited, as well as 17 earlier articles published by the founders of the methods, which are used today.

Results. In the review, current data on epigenetic regulation for gene expression at the level of DNA methylation and histone modification are discussed, in vitro model systems and model organisms are described, and modern methods for screening of epigenetically active xenobiotics are presented.

Conclusion. Modern data concerning the mechanisms of epigenetic regulation of gene expression, the usage of existing model systems and model organisms, as well as the application of various methodological approaches and techniques, allow extensive screening of xenobiotics (including drugs and compounds synthesized for national economic tasks) for epigenetic activity. The identification of epigenetically active compounds is important in terms of improving the prevention and treatment of a number of diseases and, in particular, malignant neoplasms.
Male reproductive status after the classical inguinal hernia repair
Authors: Akramov N R , Omarov T I , Gimadeeva L R , Galliamova A I
Published: November 2019

Aim. To determine the male reproductive status 18-20 years after classic unilateral herniotomy performed in childhood. Methods. Newsletters were sent to 127 patients, of whom 12 (9.45 %) responded. Male patients were invited for examination, including physical examination spermography with mixed agglutination reaction (MAR)-test, scrotum Doppler ultrasonography, prostate ultrasonography. Complete list of abovementioned examinations was performed in 10 male patients, representing 7.87% of the total number of respondents. 10 volunteers who had no medical history of inguinal hernia surgery were tested as a comparison group. Results. Sclerotic changes manifesting as testicular calcification were found in 4 (3.15%) patients who underwent inguinal hernioplasty surgery. No such findings were registered in volunteers who had no inguinal hernia surgery. Besides, 4 patients developed unilateral testicular hypotrophy of the hernia side, accompanied by an increased resistance index of parenchymal vessels in 75% of cases, which indirectly explains the causes of pathological changes in sperm. Considering small number of examined patients, the study had not enough power to state that hernioplasty surgery had the negative impact on male reproductive function; hence, it should be noted that in 7 cases alterations in the semen analysis were found, and 3 patients were infertile. These changes are likely to be related to technical defects of classic inguinal hernioplasty surgery performed in childhood. Conclusion. It is necessary to revise the use of classic inguinal hernioplasty and herniorrhaphy surgery performed in male children.