bluuebunny/crossref_metadata_2025 huggingface dataset:
Severe Acquired Hypothyroidism and Van Wyk–Grumbach Syndrome in Two Children
Authors: Nicolescu Corina Ramona , Bazus Lucie , Stephan Jean-Louis
Published: July 2024

The primary manifestations of chronic hypothyroidism in children include growth arrest, delayed skeletal maturity, and delayed puberty. In 1960, Van Wyk and Grumbach reported three girls with hypothyroidism and a combination of incomplete isosexual precocious puberty (early breast development, menstruation, and absence of pubic hair), galactorrhea, delayed bone age, and pituitary enlargement. All abnormalities regressed after appropriate thyroid hormone replacement therapy. Over the years, an increasing number of reported cases has allowed for a more precise understanding of the clinical, biochemical, and radiological phenotypes of the Van Wyk–Grumbach syndrome (VWGS). These varying clinical manifestations are thought to result from a unique pathophysiological process where the thyroid‐stimulating hormone (TSH) is a key element. We describe the cases of two patients (a boy and a girl) with severe autoimmune thyroiditis and VWGS. The clinical, biochemical, and radiological imaging characteristics were similar in both patients and included growth failure, absence of clinical goiter, markedly elevated TSH concentrations >100 mIU/L, undetectable free thyroxine levels, “normal” thyroglobulin levels, high follicle‐stimulating hormone (FSH) and prolactin levels, prepubertal levels of luteinizing hormone (LH), delayed bone age, and hyperplasia of the pituitary gland. The two patients displayed differences, especially in the absence of clinical pubertal development, moderate anemia, abnormal renal function, and moderate goiter detected via ultrasonography (in the female patient). Thyroxine replacement therapy reversed the VWGS phenotype and hypothyroidism, with satisfactory growth velocity, strictly normal thyroid function, and normal pituitary size detected via magnetic resonance imaging at the 6‐month follow‐up visit.
Supplementary Table 2 from KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Authors: Sigafoos Ashley N. , Tolosa Ezequiel J. , Carr Ryan M. , Fernandez-Barrena Maite G. , Almada Luciana L. , Pease David R. , Hogenson Tara L. , Raja Arul Glancis L. , Mousavi Fatemeh , Sen Sandhya , Vera Renzo E. , Marks David L. , Flores Luis F. , LaRue-Nolan Kayla C. , Wu Chen , Bamlet William R. , Vrabel Anne M. , Sicotte Hugues , Schenk Erin L. , Smyrk Thomas C. , Zhang Lizhi , Rabe Kari G. , Oberg Ann L. , Zaphiropoulos Peter G. , Chevet Eric , Graham Rondell P. , Hagen Catherine E. , di Magliano Marina P. , Elsawa Sherine F. , Pin Christopher L. , Mao Junhao , McWilliams Robert R. , Fernandez-Zapico Martin E.
Published: July 2024

Supplementary Table 2 includes the SNP analysis of components of the Hedgehog pathway.
Supplementary Table 1 from KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Authors: Sigafoos Ashley N. , Tolosa Ezequiel J. , Carr Ryan M. , Fernandez-Barrena Maite G. , Almada Luciana L. , Pease David R. , Hogenson Tara L. , Raja Arul Glancis L. , Mousavi Fatemeh , Sen Sandhya , Vera Renzo E. , Marks David L. , Flores Luis F. , LaRue-Nolan Kayla C. , Wu Chen , Bamlet William R. , Vrabel Anne M. , Sicotte Hugues , Schenk Erin L. , Smyrk Thomas C. , Zhang Lizhi , Rabe Kari G. , Oberg Ann L. , Zaphiropoulos Peter G. , Chevet Eric , Graham Rondell P. , Hagen Catherine E. , di Magliano Marina P. , Elsawa Sherine F. , Pin Christopher L. , Mao Junhao , McWilliams Robert R. , Fernandez-Zapico Martin E.
Published: July 2024

Supplementary Table 1 describes the characteristics of the patients used in our study.
Supplementary Figure 7 from KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Authors: Sigafoos Ashley N. , Tolosa Ezequiel J. , Carr Ryan M. , Fernandez-Barrena Maite G. , Almada Luciana L. , Pease David R. , Hogenson Tara L. , Raja Arul Glancis L. , Mousavi Fatemeh , Sen Sandhya , Vera Renzo E. , Marks David L. , Flores Luis F. , LaRue-Nolan Kayla C. , Wu Chen , Bamlet William R. , Vrabel Anne M. , Sicotte Hugues , Schenk Erin L. , Smyrk Thomas C. , Zhang Lizhi , Rabe Kari G. , Oberg Ann L. , Zaphiropoulos Peter G. , Chevet Eric , Graham Rondell P. , Hagen Catherine E. , di Magliano Marina P. , Elsawa Sherine F. , Pin Christopher L. , Mao Junhao , McWilliams Robert R. , Fernandez-Zapico Martin E.
Published: July 2024

Supplementary Figure 7 shows how oncogenic KRAS modulates GLI target gene expression.
Supplementary Figure 10 from KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Authors: Sigafoos Ashley N. , Tolosa Ezequiel J. , Carr Ryan M. , Fernandez-Barrena Maite G. , Almada Luciana L. , Pease David R. , Hogenson Tara L. , Raja Arul Glancis L. , Mousavi Fatemeh , Sen Sandhya , Vera Renzo E. , Marks David L. , Flores Luis F. , LaRue-Nolan Kayla C. , Wu Chen , Bamlet William R. , Vrabel Anne M. , Sicotte Hugues , Schenk Erin L. , Smyrk Thomas C. , Zhang Lizhi , Rabe Kari G. , Oberg Ann L. , Zaphiropoulos Peter G. , Chevet Eric , Graham Rondell P. , Hagen Catherine E. , di Magliano Marina P. , Elsawa Sherine F. , Pin Christopher L. , Mao Junhao , McWilliams Robert R. , Fernandez-Zapico Martin E.
Published: July 2024

Supplementary Figure 10 shows not differences in H3K4me1 enrichment at Ccnd1 promoter in mutant KRAS cells.
Figure 3 from KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Authors: Sigafoos Ashley N. , Tolosa Ezequiel J. , Carr Ryan M. , Fernandez-Barrena Maite G. , Almada Luciana L. , Pease David R. , Hogenson Tara L. , Raja Arul Glancis L. , Mousavi Fatemeh , Sen Sandhya , Vera Renzo E. , Marks David L. , Flores Luis F. , LaRue-Nolan Kayla C. , Wu Chen , Bamlet William R. , Vrabel Anne M. , Sicotte Hugues , Schenk Erin L. , Smyrk Thomas C. , Zhang Lizhi , Rabe Kari G. , Oberg Ann L. , Zaphiropoulos Peter G. , Chevet Eric , Graham Rondell P. , Hagen Catherine E. , di Magliano Marina P. , Elsawa Sherine F. , Pin Christopher L. , Mao Junhao , McWilliams Robert R. , Fernandez-Zapico Martin E.
Published: July 2024

Gli2 is required for the regulation of Ccnd1 downstream of oncogenic KRAS. A, Heatmap of GLI target gene expression in 1012U cells at 12, 24, 48, and 72 hours posttreatment with doxycycline (Dox). B, Relative gene expression of Ccnd1 by qPCR in mouse pancreas tissue from Cre, CRG, KC, and KCRG mice. C, Western blot showing expression of p-ERK, total ERK, and CCND1 in 1012U −Dox and +Dox cells at 12, 24, 48, and 72 hours post treatment. Vinculin is used as the loading control. D, Relative gene expression of Ccnd1 and Gli2 by qPCR after the knockdown of Gli2 by siRNA in 1012U cells +Dox cells (72 hours treatment; P < 0.05 and P < 0.001). E, Western blot (left) and protein quantification (right) representing expression of CCDN1 and GLI2 in 1012U cells +Dox, after the knockdown of Gli2. Vinculin is used as the loading control. F, Western blot (left) and protein quantification (right) representing expression of CCDN1 and GLI2 in 1012U cells +Dox and murine KC cell line transfected with Gli2, ∆NGli2, or empty vector (control). Vinculin is used as the loading control. G, Top: Graphical representative of mouse Ccnd1 promoter region with (red) diamond indicating candidate Gli2-binding site. Bottom: Graph representing enrichment (percent input) of GLI2 at the Ccnd1 promoter in 1012U +Dox cells (72 hours treatment; P < 0.05).
Ambiente informacional de observatórios universitários de ciência, tecnologia e inovação: proposta de modelo
Authors: Melo Rinaldo Ribeiro de , Santos Raimundo Nonato Macedo dos
Published: July 2024

Science, technology and innovation observatories are structures capable of organizing large amounts of data and providing ready-made information to users. Studies that focus on their development are necessary and can serve as a basis to streamline the processes of availability and dissemination of indicators. Thus, the objective of this study is to propose a model of informational environment for science, technology and innovation observatories, aimed at university institutions. This is an investigation with a qualitative approach and is characterized as an exploratory, documental and bibliographic research. A model of informational environment for university observatories of science, technology and innovation was presented. The model is formed by four axes: 1) information sources; 2) specialized staff; 3) instruments and technology; and 4) informational products. It is inferred that the informational environment model presented, besides being fundamental for the development and operation of university observatories of science, technology and innovation, also represents an expansion of the structural and operational understanding of the functioning of observatories of science, technology and innovation.
A indexação da informação jurídica: mapeamento sistemático na área de Ciência da Informação
Authors: Silva Giseani Bezerra da , Correa Renato Fernandes , Fujita Mariângela Spotti Lopes
Published: July 2024

This paper addresses the information processing, more precisely, the theme of the indexing of legal information. Its objective is to analyze the scientific production on the theme in the area of Information Science, aiming at the elaboration of a systematic mapping of literature and identification of an overview of these publications. This is a theoretical, exploratory and descriptive research, with a qualitative and quantitative approach. The bibliographic databases searched were BRAPCI, LISTA, Redalyc, SciELO, Scopus and CAPES Periodicals Portal. The works analyzed point to the librarian’s need for specialized knowledge about the indexing of legal information. All articles dealt with the scarcity of works and discussions about the theme, and the need for further research in order to minimize noise at the time of searching. The conclusion is that the production of scientific knowledge disseminated by scientific journals on the theme, in the period from 2002 to 2022, includes ten articles by Brazilian authors associated mainly with universities. The articles bring important contributions to the research and practice of indexing legal information, but the problem of scarcity of works persists.
Uso de evidências científicas por enfermeiros na Região Centro Oeste do Brasil
Authors: Rocha Maria Gisélia da Silva , Villela Edlaine Faria de Moura , Galvao Maria Cristiane Barbosa , Ricarte Ivan Luiz Marques
Published: July 2024

Os profissionais de saúde, entre os quais estão os enfermeiros, precisam se preocupar diariamente em como acessar, selecionar e usar as melhores evidências científicas disponíveis, tarefa complexa em decorrência da produção exponencial de informações científicas no campo da saúde. Este estudo exploratório descritivo de análise quantitativa levantou barreiras e facilitadores para o uso de evidências científicas por profissionais de enfermagem na Região Centro-Oeste do Brasil. Participaram do estudo 115 enfermeiros que atuavam na prática clínica no momento da pesquisa. Observou-se que os recursos informacionais mais utilizados pelos participantes do estudo são artigos científicos, consulta a outros profissionais da saúde e diretrizes clínicas. No topo dos facilitadores e das barreiras para uso de informações científicas destacaram-se, respectivamente, a educação continuada e o excesso de tarefas. Conclui-se que o uso de evidências científicas por profissionais de enfermagem demanda o desenvolvimento de políticas organizacionais bem estabelecidas para busca e uso de informações associadas à capacitação continuada, à remuneração adequada e à revisão da carga horária de trabalho dos profissionais de enfermagem.
Contribuições da Fundação Ford à formação e consolidação de campos científicos no Brasil
Authors: Rocha Ednéia Silva Santos
Published: July 2024

No cenário da cooperação internacional a Fundação Ford se destaca, pois a partir do final da Segunda Guerra Mundial, assumiu uma posição de liderança em relação a outras agências de fomento, pois possui um volume substancial de recursos, o que lhe permite atuar em várias partes do mundo fomentando ações para produção e divulgação do conhecimento. Assim, o objetivo do artigo é examinar as contribuições da Fundação Ford na formação ou consolidação de campos científicos no Brasil. Para analisar como o apoio institucional e financeiro da fundação foi relevante para alguns campos científicos, recolheu-se um conjunto de dados que permitiu avaliar e conhecer os impactos do fomento nas comunidades científicas. Para a coleta dos dados empíricos procedeu-se inicialmente a uma pesquisa bibliográfica, por meio de consultas a catálogos de bibliotecas e base de dados nacionais e internacionais. A partir daí, coletou-se e organizou-se os dados a partir de fontes primárias como os relatórios anuais da fundação e fontes secundárias como base de dados de doações Grants Database. Conclui-se que não há evidências para se afirmar que o financiamento da Fundação Ford foi ou é imprescindível ao desenvolvimento científico do Brasil, mas de alguma forma ela desempenhou um papel fundamental na construção e apoio a comunidades de pesquisadores.
The Skull of the Syntax: On Translating Eisenstein's Capital Diaries
Authors: Kunichika Michael
Published: July 2024

The author discusses his translation of Sergei Eisenstein's Capital Diaries, focusing on such topics as Eisenstein's reflections on his own writing, the context of literary modernism in which he wrote, and the strains on psyche and syntax that the diaries reveal. It discusses the range of literary sources that Eisenstein made use of in the diaries, in particular the works of James Joyce and Velimir Khlebnikov. Also discussed are the challenges of translating the diaries, which constitute, all at once, a record of daily life, a series of cultural and political critiques, and a compendium of material the Soviet filmmaker planned to use in his (ultimately unrealized) film based on Karl Marx's Das Kapital. The diaries served as a workshop for refining various concepts and methods such as montage and dialectical thinking, and this too is addressed.
The Capital Diaries: A New Selection
Authors: Eisenstein Sergei
Published: July 2024

Almost fifty years after the first publication of Sergei Eisenstein's “Notes for a Film of Capital” in the pages of October, “The Capital Diaries: A New Selection” presents extensive new extracts from the Soviet filmmaker's notebooks from 1927 and 1928, drawing from over five hundred pages of notes, images, press clippings, drawings, and diagrams in which Eisenstein puzzles over his (unrealized) film based on Karl Marx's Das Kapital. This new selection emphasizes the experimental, diaristic, and proto-cinematic character of the material to present both a fuller sense of Eisenstein's work on the film and the central use of images to the process. What emerges is an autotheoretical experiment involving psychoanalysis (including the filmmaker's own), “intellectual attractions,” typage (non-professional actors), the film October, and the many ways in which James Joyce's Ulysses, especially the “inner monologue,” served as creative resources and experimental instruments for the Capital project.
A taxonomic review of Sueus Murayama, 1951 ambrosia beetles (Coleoptera: Curculionidae: Scolytinae: Hyorrhynchini) aided by molecular phylogenetic analyses
Authors: COGNATO ANTHONY I. , SMITH SARAH M. , SCHIFFER MATTHEW , LI YOU
Published: July 2024

Four Sueus Murayama, 1951 species occur in Southeast Asia and Oceania. They all likely have a female-biased haplodiploid inbreeding mating system and feed on symbiotic ambrosia fungi. These life history traits increase the potential of adventive events. Indeed, Sueus has been recently discovered on the Caribbean island of Martinique. Morphological variation has been observed among some populations of Sueus niisimai (Eggers, 1926), which questioned species boundaries. Given the beetle’s potential economic importance, we provide a molecular phylogeny as a foundation for systematic study and review the status of the known species. We sequenced a total of 1117 nucleotides from mitochondrial COI and nuclear CAD genes for 25 specimens. Parsimony and Bayesian phylogenies were similar in topology and demonstrated the sister placement of S. granulatus (Eggers, 1936) to the other Sueus species, reciprocal monophyly of S. niisimai and S. pilosus (Eggers, 1936) status restored, the monophyly of S. obesus Browne, 1977 and elevated levels of nucleotide divergence (interspecific = 16–22%). Sueus chatterjeei Smith & Cognato sp. nov. (India) and Sueus insulanus Schiffer, Smith & Cognato sp. nov. (Papua New Guinea) are described. Hyorrhynchus granulatus Eggers, 1936 is removed from synonymy with Hyorrhynchus lewisi Blandford, 1894 and reinstated as a valid species, Sueus granulatus (Eggers, 1936) status restored, comb. nov. A key to the eight recognized species is given. In addition, the identity of the Martinique species is revised as S. pilosus. Geographic distribution of species and the potential existence of cryptic species are discussed.
Association Between Serum 25(OH)D Concentration and Clinical and Biological Complications in Pediatric Patients with Sickle Cell Disease
Authors: Tall Fatou , Kandji Pape , Ndour El , Mbancké Serigne , Djité Moustapha , Barry Oumou , Cissé Aynina , Sall Philoméne , Gueye Papa
Published: July 2024

In addition to its role in phosphocalcic and bone metabolism, vitamin D also plays a global role in health. Despite high levels of sunshine, vitamin D deficiency remains a public health problem in sub-Saharan Africa, where sickle cell disease predominates. This study aimed to investigate an association between serum vitamin D (25(OH)D) levels and the occurrence of clinical and biological complications. The study was carried out in children with SS sickle cell disease aged 1 to 17 years (75 patients) matched to 17 AA controls. Plasma 25(OH)D concentration was obtained by immunoassay. The clinical complications studied were caso-occlusive crisis, osteomyelitis, osteonecrosis, acute chest syndrome, and priapism. Biological parameters included blood count, ionized calcium, and phosphorus. Statistical analysis was performed using R Studio 4.1.2 software. The significance threshold was 5%. Our study revealed a high prevalence of vaso-occlusive crisis (97%). Vitamin D deficiency was found in 4% of patients (3 SS patients) and 36% (27 SS patients) had a plasma concentration between 10 and 30 ng/ml. The association study revealed a negative association between vitamin D and the number of vaso-occlusive crises (r = -0.51; p < 0.001). We noted a positive association between vitamin D and blood calcium (r = 0.347; p < 0.002), phosphatemia (r = 0.347; p < 0.002), and hemoglobin (r = 0.243; p < 0.035). Vitamin D is correlated with certain clinical and biological complications. Vitamin D supplementation in children with sickle cell disease (SS) would therefore be relevant for better management of this disease.
The Contribution of Host Galaxy Properties in X-Ray Active Galactic Nuclei Clusters
Authors: Mekonen Gutu , Kare Anno
Published: July 2024

In this study, the influence of host galaxy properties on X-ray active galactic nuclei (AGN) clusters was investigated using multiwavelength data. X-ray data from the eFEDS main catalog, optical and near-infrared data from the fourth data release of KiDS/VIKING, and mid-infrared data from WISE were utilized. By integrating these datasets and employing the CIGALE code, the star formation rate, luminosity, and stellar mass of the host galaxies were estimated. The analysis reveals significant associations between luminosity, stellar mass, and star formation rate, providing valuable insights into AGN activity. Furthermore, AGN clusters were compared with non-AGN clusters to uncover distinctive characteristics. AGN clusters exhibit differences in their population across various luminosity levels. Interestingly, a significant proportion of AGN clusters is concentrated in the middle range of luminosity (45-46 measured in logL(0.5-2.0 keV)) for both low and high redshift classifications. Additionally, galaxies hosting AGNs detected in X-ray emission tend to fall within a specific range of stellar mass (10-11 measured in log(M⋆(M⊚)). This stellar mass range is populated by a substantial number of AGN galaxies, irrespective of their redshift classification. Moreover, a significant population of X-ray AGN is concentrated within the star formation rate range of 1.5-2.5 (expressed in log(M⊚ yr-1)) in both low and high redshift regions. By analyzing the dependencies on luminosity, stellar mass, and star formation rate, this study provides valuable insights into the correlation and relationship between AGN clusters and their host galaxies. The comparison with non-AGN clusters and the integration of multiwavelength data from eFEDS, KiDS/VIKING, and WISE enhance the depth of analysis, contributing to a comprehensive evaluation of AGN clusters. These findings advance our understanding of the complex relationship between AGN clusters and host galaxy properties in the field of astrophysics.
Recycling of Waste PET Plastic on Asphalt, by Using Application of Response Surface Methodology: Effect of Production Process Parameters
Authors: Sofo Hassan , Mohammed Mohagir , Sidick Batran
Published: July 2024

Plastic, polymers of variable compositions have become object of common use and difficult to digest by micro-organisms, especially single-use plastic waste, such as polyethylene terephthalate (PET) water canisters. These polymers are source of environmental pollution. Therefore, it is important to manage theme in the good way to protect environment. In this study, different conditions of waste plastic PET (Polyethylene Terephthalate) recycling on asphalt were optimized. Response Surface Methodology (RSM) using the Doehlert experimental design has been employed in the optimization. The independent variables considered were bitumen (5-8%), PET (0-12%), Mixing temperature (150-160°C) and Mixing time (20-30min). Four-second order polynomial models were generated. The responses obtained by the models were well described as: specific density (Y.SD), penetrability (Y.P), softening point (Y.SP), and flash point (Y.FP) of the process with satisfactory fits in terms of absolute average deviation, bias factor and accuracy factor. The optimum responses were 1,04 as specificity gravity (Y.SG), 60*(1/10mm) as penetrability at 25°C, 100g and 5sec (Y.P), 50°C as softening point (Y.SP), and 242°C as flash point (Y.FP). The statistical relation between the four independent variables and the process responses were well described.
The Functionality of Global Quality Management in the Dynamic and Global Environment of Mergers, Acquisitions, and Strategic Partnerships - Adoption of a Systematic Process Concept
Authors: Bashan Aviva , Notea Amos , Jacob Alon
Published: July 2024

Purpose: To explore the functionality of the quality management processes at the global level and understand its complexity and multiple dimensions. Design/methodology/approach: The researchers use a novel systems perspective to explore international standards ISO 9001/9004 capacity to encompass this complexity and analyze the stages by which global multinational organizations develop. In-depth interviews with experts (CEOs, quality managers, and global managers) from 18 international firms were some of the qualitative methods used in the research, along with content analysis, observations, and other methods. The study addresses the philosophy of global quality management and emphasizes the need for inter-organizational coordination and process management. Findings: The results of the qualitative tools showed that the existing definitions in ISO 9004/9001 have made it challenging to address the level of process complexity in international organizations. The main recommendations of the study are the following key points for expanding and refining the existing process concept for a global reality: 1) adopting a systems approach for analyzing the development of a global quality function in complex, multinational companies. 2) extending the classic process approach to open, multi-interface systems oriented towards mutual strategic, operational, and marketing processes. Originality/value: In this article, we suggest an innovative, integrated systems approach to multinational quality management based on shifting from the traditional emphasis on separate operations and manufacturing sites toward a comprehensive perspective that considers the interdependence and coordination among locations. This novel analysis and mapping process offers a comprehensive view of coordinating interdependence between elements comprising an international global process system. It expands the ‎classical approach and provides a basis for ‎developing a global, networked QMS. The current study might be useful for organizations that implement quality management systems in multinational companies. The study is part of vast academic research on international strategy in the global competitive landscape.
Capgras Syndrome with Non-Violent Behaviour Presenting in Postpartum Period: Case Study with Literature Review
Authors: Numan Nabil
Published: July 2024

Background: Capgras syndrome (CS) is one of the delusional misidentification syndromes (DMS) characterized by the belief by the patient that the close person, usually a close relative or family member is replaced by an imposter who looks physically the same. Since the first case of Capgras syndrome was described in 1923, the published literature is confined to a small number of case reports and a single case series. Capgras syndrome rarely occurs in postpartum period; there are few references in the literature to any of the delusions of misidentification occurring in a post partum period. Moreover, some authors described Capgras syndrome as frequently involving hostility, violence and risk of neglect towards an object of delusional misidentification. Their reports based on single cases report or small case series that may be subject to significant reporting bias. This case outlined here on a female patient affected by Capgras syndrome in post partum period with brief review of the literature. Case presentation: A 32-year-old woman presented to the psychiatric clinic for a delusional belief that newborn had been replaced by another one. Capgras delusion was developed after caesarean section on her 12th postpartum day. The patient was healthy individual whose Capgras syndrome was not linked to any psychiatric or neurological states in the past. Anxiety and depressive symptoms followed progressively without postpartum psychosis. Though she has a fixed belief, which is that her baby was replaced by another one, she did not show any psychotic features or aggression behaviour. Conclusion: In this case report, Capgras syndrome is typically a monothematic delusion (delusion about the baby may have an altered identity or replaced by another one) and is not accompanied by other delusions. Also, it displays the course of anxiety and depression in the period of postpartum period that accompanied with Capgras syndrome. The patient has no postpartum psychosis, only a delusion about the baby replaced by another one. Though her ambivalent emotions toward the baby, the patient did not show any hostility, aggression behaviour or violence and denied thoughts of harming baby.
Polymers in the Textiles and in the Construction Industry
Authors: Wahab Hebah , Gund Tamara
Published: July 2024

Ionic solids, ceramics and most polymers and plastics are insulators, they do not conduct electrical current. Plastics are materials that can be formed into various shapes by the application of pressure or heat. Plastics are classified into thermosetting plastics, thermoplastic material, or an elastomer. A thermosetting plastic cannot be reshaped readily as it’s made from an irreversible reaction. Thermoplastic materials can be reshaped, for example polyethylene polymer used in the making of milk containers. Elastomers are plastics with elastic behavior or rubbery plastics, as they can be subject to stretching and bending. Polymers can be either naturally occurring from animals or plants or synthesized in chemical plants or chemical laboratories. This work is aimed to identify the polymers that are used in the textile industry and the polymers used as fill in materials in the construction industry, to find polymers that are less toxic with similar properties as PVC in the textile industry due to the environmental concerns that comes with using PVC, to know whether poly vinyl chloride is still used in the textile industry in the United States, and to find suitable polymers used as fill material in the construction industry.
Antimicrobials Use by Smallholder Dairy Farmers in Peri-Urban Area of Nakuru Kenya: Knowledge, Attitudes and Practices
Authors: Njie Mariama , Bebe Bockline , Orenge Caleb
Published: July 2024

In dairy intensification, mastitis infections become prevalent and induce frequent Antimicrobial Use (AMU), sometimes inappropriately. This poses public health risks because of growing Antimicrobial Resistance (AMR), which calls for stewardship programs informed by Knowledge, Attitude and Practices (KAPs) about AMU and AMR to halt or reverse the worrying trend. Data was obtained in cross sectional survey conducted in four peri-urban wards around Nakuru city in Kenya. Randomly selected sample farmers (n=124) with free-grazing, semi-zero-grazing or zero-grazing dairy management, representing increasing dairy intensification levels provided data on the KAPs. Chi-square test statistics was fitted to establish associations between KAPs and dairy intensification levels. Among the sample farmers, six in ten (58.8 percent) had intensified dairy production, at least six in ten were marketing milk through informal outlets and were using antimicrobial drugs. Compliance with the withdrawal period was high and increased (p<0.05) with increasing intensification from free-grazing to zero-grazing. Within antibiotic withdrawal period, at least seven in ten farmers did not sell milk, fewer than four in ten consumed their milk at home and fewer than three in ten fed the milk to calves. Though independent of dairy intensification level (p>0.05), using antimicrobials for mastitis treatment increased while sourcing information on antimicrobial use from extension and veterinary officers decreased, with increasing intensification level. Farmers with some training on prudent antimicrobial use and with positive attitudes that milk from antimicrobial treated cows is unsafe, antimicrobial resistant pathogens and residues can be passed from milk to humans, mastitis can be treated without antimicrobial drugs, and antimicrobial residues can end up accumulating in the soils increased (p>0.05) with increasing dairy intensification levels. These results show that regarding AMU and AMR, farmers become more knowledgeable, with positive attitudes and good practices as they intensify their dairy management. The implication is that intensification of dairy management motivates farmers to gain more knowledge, acquire positive attitudes and apply good practices towards responsible prudent use of antimicrobials in livestock. Therefore, strengthening stewardship with targeted training and sensitization can foster prudent and responsible antimicrobial use.
Validating the Skills of Satellite Rainfall Products and Spatiotemporal Rainfall Variability Analysis over Omo River Basin in Ethiopia
Authors: Asefw Elsabet , Ayehu Getachew
Published: July 2024

Recently created long-term and regionally dispersed satellite-based rainfall estimates have emerged as crucial sources of rainfall data to assess rainfall's spatial and temporal variability, particularly for data-scarce locations. Objective (the general): The purpose of this paper is to assess the skills of nine selected satellite rainfall estimates i.e., (ARC 2.0, TRMM 3B42, CHIRPS v. 2.0, TAMSAT 3.1, CMORPH v. 1.0 adj., PERSIANN CDR and DNRT, and MSWEP v. 2.2) and understand Spatio-temporal variability of rainfall over the Omo River basin using the best performing product. Method: The validation analysis was done by using a point-to-grid-based comparison test at different temporal accumulations. MSWEP was selected as the best product to analyze the long-term trend and variability of rainfall over the Omo-River basin from 1990-2017. The coefficients of variation (CV) and the standardization rainfall anomalies index (SRAI) were used to examine rainfall variability, while the Mann-Kendall (MK) and Sen slope estimators were used to examine the trend and magnitude of rainfall patterns. Results: The overall statistical, categorical, and volumetric validation index results show that the MSWEP is the best performing rainfall product followed by CHRIPS, 3B42, and TAMSAT according to their order of appearance than the remaining products (i.e., ARC, RFE, PER CDR, PER DNRT, and CMORPH). The CV result with the relatively highest monthly variability (CV > 30%) was observed in some southern, northern, southeastern, and central parts of the study area. In general, the overall annual CV shows almost no variation in the entire basin except in the lower part because of the region's prevalent topographic variances, which ranged from 3455 to 352 m.a.s.l. In addition, the highest seasonal positive and negative anomalies are observed in each season in the entire basin. These abnormalities can result in significant floods and droughts that unquestionably influence the basin and its resources. Conclusion: In general, the basin has an increasing trend in the southern portions and a declining trend in the central to northern tip parts of the basin, as can be observed from the annual average MK trend tests. The basin has experienced a greeter variation but is not significant except in some parts of the basin.
Thermodynamics of Heat Inactivation of Aeromonas hydrophila in Soymilk of Varying Initial pH and Sugar Levels
Authors: Tersoo-Abiem Evelyn , Ariahu Charles , Igyor Micheal
Published: July 2024

The thermodynamics of thermal inactivation of Aeromonas hydrophila in soymilk of varying pH (6.0-7.0) and sugar concentration (0-10%) were studied at a temperature of 50-65°C using kinetic parameters generated through the Classical thermobacteriology assumption of a log-linear relationship between A. hydrophila survivors and heating time. The activation enthalpy (ΔH#), activation entropy (ΔS#), activation energy (Ea) and frequency factor (Ko) for thermal inactivation of A. hydrophila in the soymilk samples were also obtained. Thermal inactivation of the organism followed first order reaction kinetics. The heat destruction rate constant (k) decreased with increase in heating temperature. The activation energy ranged from 210.98 to 215.28 kJ/mol increasing with decrease in pH and increase in sugar concentration of soymilk. The isokinetic temperature (TC) obtained varied from 55.95 to 56.62°C with inactivation of A. hydrophila exhibiting true compensation effect, with a Gibbs free energy of 82.86 kJ/mol. A combination of temperature, pH and sucrose significantly influenced inactivation of A. hydrophila in soymilk, following a similar mechanism being driven by entropy. Optimum safety from A. hydrophila can be achieved through application of multifactorial hurdles in soymilk processing. The thermodynamic data obtained will be useful to optimize thermal processing conditions for soymilk targeting A. hydrophila.
Jugulocarotid Trauma in Civil Practice: About Three (3) Cases
Authors: Konaté N’faly , Nderagakura Sixte , Diarra Kassim , Sanogo Harouna , Guindo Boubakary , Ansari Mohamed , Kone Fatogoma , Cissé Naouma , Coulibaly Kalifa , Soumaoro Siaka , Sinkare Kadiatou , Bouare Ibrahima , Keïta Mohamed
Published: July 2024

Introduction: jugulocarotid trauma is rare and serious. They can be immediately life-threatening due to the impact of serious hemorrhage or obstruction of the upper airways. Objective: The objective of this work is to describe the clinical and therapeutic aspects of these lesions. Observations: The time taken to treat our patients was less than 12 hours in all our patients. A pressure dressing was placed in two patients. All our patients benefited from a preoperative assessment with Rh grouping and possibly a blood transfusion as needed. Exploratory cervicotomy was performed in all patients with, as appropriate, repair or ligation of the internal jugular vein and suture of the carotid wounds. All patients received antithrombotic treatment, antibiotic prophylaxis and analgesic treatment at the end of the procedure. The postoperative course was simple in all cases. Conclusion: vascular wounds of the neck constitute an emergency. Prehospital care is an essential step in the management of these lesions. Faced with massive hemorrhage, only immediate surgical exploration associated with resuscitation measures determines the survival of patients. In other cases, an imaging assessment may be necessary in stable patients.
An Engineered Assessment System to Manage Demand Reduction Initiatives
Authors: Hernandez Alejandro , Achor Nathanael , Franks Courtney , Gillogly William , Groller Randall , Hatch William , Ulmer Nicholas
Published: July 2024

The Joint Warfighting Concept is a framework for how the United States will fight in the future security landscape. To successfully carry out these new concepts, the military services must find ways to lessen the logistics burden at the strategic, operational, and tactical levels. Only by reducing the demands on its current and planned sustainment systems can the United States continue to be a dominant force on the world stage. However, defense agencies such as the Logistics Functional Capability Board lack a quantitative, credible, repeatable process to effectively assess and manage demand reduction initiatives. This paper is based on work from a student/faculty team that created an assessment system for demand reduction initiatives. Discussion highlights the systems engineering techniques that were used in the effort, which includes but is not limited to stakeholder analysis, functional analysis, morphological analysis, and value modeling. The blended qualitative and quantitative methods focused on user and stakeholder needs to create a process system to evaluate technologically disparate, multicriteria systems. The team expects that the resultant assessments system’s applicability to a range of demand reduction initiatives would be of interest to organizations that must prioritize technology proposals, as well as perform trade-off analysis. Additionally, the approach to create the assessment system has the flexibility to adapt to changes in the stakeholders’ requirements from the reduction initiatives, as well as the ongoing evolution of the warfighting concepts.
Occupational Health and Safety in the RMG Sector of Bangladesh: An Enormous Order
Authors: Kamal Takmina , Tarzid Surina
Published: July 2024

Today it’s a matter of concern to ensure the occupational health and safety in the Ready Made Garments (Hereinafter referred to as RMG) sector of Bangladesh. Some accidents such as the Tazrin Fashion Fire and the Rana Plaza collapse draw attention - to the critical situation the workers of Bangladesh are working in, and to what extent they are at risk. It's a matter of regret and shame that, it has been forgotten that the RMG sector not only contributes to our national economy but also emancipates the poor people from poverty and hunger, This sector also highlights our country in front of the world. Textiles and clothing account for earnings a lot in Bangladesh, where most of these come from the apparel sector. This sector has a crucial role in alleviating poverty in Bangladesh. However, rapid growth, as well as the failure of the Bangladesh government to enforce its building and labour regulations, resulted in worker abuse and unsafe for poorly constructed factories. This series has been elucidated to what extent occupational health and safety covered and their impact, also focuses on how the rights of the worker are violated and analysis the duties and responsibilities of the related persons such as occupiers of the factories, Trade Unions, Collective Bargaining Agent, Inspector, buyer and so on. It also focuses the statutory protection to ensure Occupational health and safety. Finally, put some recommendations or ways out to ensure the safe and sound working conditions of the workers of the RMG sector in Bangladesh.
About Absolute Convergence of Fourier Series of Almost Periodic Functions
Authors: Talbakov Farkhodzhon
Published: July 2024

The current stage of development of the theory of almost periodic functions is characterized by a desire for analysis and processing of a huge amount of accumulated scientific and practical material. The theory of almost periodic functions arose in the 20-30 s of the twentieth century; currently, extensive literature has accumulated on various issues of this theory. Long before the creation of the general theory of almost periodic functions, the outstanding Riga mathematician P. Bol drew attention to such functions. For functions of many variables f(x1, x2,...xp), Bol considered the corresponding multiple Fourier series and, in p-dimensional Euclidean space, a straight line passing through the origin: x1=a1 t, x2=a2 t,..., xp=apt, where a1, a2, ..., ap - some real, non-zero numbers. Considering the value of the function f(x1, x2,...xp) on this line, he obtains a function of one variable φ(t) = f(a1 t, a2 t,...ap t) and proves that this function is almost periodic. With some choice of numbers a1, a2, ..., ap - it may happen that this function is periodic. However, if the numbers a1, a2, ..., ap are linearly independent, then you can easily make sure that the function will not be a periodic function. Further development of the problem was carried out by the French mathematician E. Escalangon. However, the main significant drawback of the results of Bol and Escalangon was that from the very beginning, starting with the definition of almost-periodic functions, they introduced into consideration a fixed system of numbers a1, a2, ..., ap associated with the almost-period (τ). This drawback was eliminated by the Danish mathematician G. Bohr, who developed in general terms the theory of continuous almost-periodic functions. Bohr's research in its methods was closely related to Bohl's research. However, Bohr did not impose restrictions such as Bohl’s inequality in advance for the almost period. The results obtained by Bol and Bohr were based on the deep connection between almost periodic functions and periodic functions of many variables. The article examines the question of sufficient conditions for the absolute and uniform convergence of Fourier series of uniform almost periodic functions in the case when the Fourier exponents have a single limit point at zero, i.e. λk→0 (k→∞). In this case, the Laplace transform is used for the first time as a structural characteristic.
Antimicrobial Resistance and Innovation in the Development of Antimicrobial Reagents
Authors: Sahgal Shivangi , Srivastava Deepa
Published: July 2024

The effectiveness of our antibiotics and other antimicrobial treatments is at risk due to the global public health concern known as antimicrobial resistance. The emergence of resistant diseases presents a serious problem for society as well as for medical professionals. This article delves into the complex problem of antimicrobial resistance (AMR), examining its causes, effects, and possible remedies. The creation and application of efficient reagents, which are essential for research, diagnosis, and the creation of innovative treatments, is a critical component in the fight against antimicrobial resistance (AMR). The significance of these agents and how they can help lessen the impending problem of antimicrobial resistance is reviewed. An increasing worldwide health concern, antimicrobial resistance poses a danger to the efficacy of many of our most powerful medications. It is critical to create new antimicrobial reagents to counter this impending threat. But there are many obstacles in the way of developing effective antimicrobial reagents. In order to present a thorough overview of the current state of AMR and its solutions, this article explores the various obstacles and creative approaches in this sector. The quick evolution of resistance in microbial populations is one of the main obstacles to the development of antimicrobial reagents. Many new medications quickly lose their effectiveness due to the astonishing speed at which bacteria and other pathogens adapt to them. The overuse and abuse of currently available antimicrobial drugs is aggravating this progression. Consequently, there is a constant struggle to keep developing novel reagents ahead of these changing microbes. One costly and time-consuming part of developing antimicrobials is getting regulatory approval. The strict guidelines put in place by regulatory agencies to guarantee the security and effectiveness of new drugs may cause a delay in their introduction into clinical settings.
Effectiveness Analysis of the Combined Detection of CEA, SCC, CYFRA21-1, NSE and ProGRP for Early Diagnosis of Lung Cancer
Authors: Zhou Shufang , Ge Xiaojun , Yang Zhifang , Zeng Fei
Published: July 2024

Objective To explore the diagnostic value and application effect of the combined detection of CEA (carcinoembryonic antigen), SCC (squamous cell carcinoma antigen), CYFRA21-1 (soluble fragment of cytokeratin 19), NSE (neuron specific enolase) and proGRP (gastrin releasing peptide precursor) in early lung cancer. Method 66 patients who admitted to the hospital from April 2019 to February 2024 were selected as the early stage lung cancer group and the other 159 patients were selected as the benign lung group, in which all subjects were tested for NSE, CEA, ProGRP, CYFRA21-1, and SCC levels and were confirmed by histopathological analysis. In ROC analysis, the cut-off point, AUC, accuracy, sensitivity and specificity between single and combined detection indicators are analyzed. Result The size of cut-off point, AUC, accuracy, sensitivity, specificity, positive and negative detection rate and accuracy rate is 0.3072, 0.790, 89.33%, 0.894, 0.893, 89.40% (59/66), 89.31% (142/159) and 89.33% ((142+59)/225) respectively and it is obviously superior to those of single detection method. Meanwhile, indicator of SCC showed the worst performance by single detection. Conclusion The combined detection indicators have high diagnostic value in early diagnosis of lung cancer, and the sensitivity, positive detection rate, AUC value and accuracy have been significantly improved.
Seismic Prediction Technology for Channel Sand Body of Fuyu Oil Layer in Xinmin Area, Southern Songliao Basin
Authors: Mingli Shao , Xiaoliang Lian , Guodong Liu , Weiwei Qu , Qiaojie Yan , Chuntao Jiang , Jia Zhao , Lei Wang
Published: July 2024

The Fuyu reservoir in Xinmin area is a delta plane-front facies deposit, and the channel sand body in this area is the main reservoir of oil and gas. Due to the complex sedimentary environment, the sand body shows great variation in thickness and distribution. In this study, the method of combining well vibration, model forward modeling and stratum slicing are used to predict the sandstone bodies of different thickness successfully. Especially for the thin sand body with a thickness of less than 5 meters, this study found that the GR curve can effectively distinguish sandstone and mudstone through the intersection analysis of logging curves, and applied the GR curve co-simulation inversion technology to perform fine characterization. In addition, the study also reveals that the northeastward twisting fault zone in Xinmin area is a favorable accumulation area of the reservoir, which provides a new direction for oil and gas exploration. This study not only improves the accuracy of sandstone prediction, but also provides a valuable reference for oil and gas exploration under similar complex geological conditions.