bluuebunny/crossref_metadata_2025 huggingface dataset:
An Artificial Appetite: The Nineteenth-Century Struggle to Define Habitual Drunkenness
Authors: Korostyshevsky David
Published: September 2024

summary: After discovering in 1811 that alcohol existed as a discrete chemical substance in all intoxicating drinks, physicians reconsidered the individual’s responsibility for becoming a compulsive drinker. Looking to science and medicine for legitimacy, temperance reformers ascribed a deleterious agency to alcohol and personified it as an agent of physiological destruction. Alcohol destroyed the body and transformed natural alimentary desires into a compulsive artificial appetite for alcohol. Reformers, prohibitionists, and physicians were troubled that alcohol possessed the ability to destroy the physical capacity for the power of choice. Ascribing agency to alcohol destabilized long-standing understandings of intemperance as a vice and imbued habitual drunkenness with medical meanings. However, most professionals remained anxious about absolving the habitual drunkard of all responsibility, especially for taking the first drink. An inchoate attempt to capture the medical and moral dilemmas of compulsion, habitual drunkenness represents a conceptual missing link in the genealogy of addiction.
A Clinic for the People: Toward an Antiracist Psychiatry at the Tuskegee Institute 1947–1965
Authors: Smith Kylie M.
Published: September 2024

summary: From 1947 until 1963, a small group of psychiatrists from the Tuskegee Veterans Administration Hospital ran a Mental Hygiene Clinic designed to provide outpatient care and education to the Black residents of Macon County, Alabama. In an analysis of the clinic and the work of its Director, Dr. Prince Barker, we see the ways that Black psychiatrists tried to develop an antiracist approach to psychiatry and to develop their own autonomy in segregated Alabama. But there were limitations to this work. Tensions between the state funding body, local politics, and the internal racism of psychiatry itself all made it difficult for Tuskegee psychiatrists to provide alternatives to care beyond the veil of the color line.
A Family Affair: Black Family Networks and the 1822 Vesey Conspiracy
Authors: Iverson Justin
Published: September 2024

Abstract: In 1822, white authorities in Charleston, South Carolina, discovered a major uprising among the city's free Black and enslaved population. After more than 100 people were arrested for their roles in the putative plot, sixty-seven people were convicted and either executed or banished from the country. While the episode, known as the Denmark Vesey conspiracy after the uprising's ringleader, is well-known to historians more generally, we know much less about how it affected the lived experiences of Black Charlestonians and how it influenced Black family networks. Although we know that women and sometimes children participated in slave insurrections like Vesey's conspiracy, we do not know how rebels used kinship ties to mobilize their resistive movements or what kind of precise impact violent resistance strategies had on Black communities in early America more broadly. Yet when analyzed through Black family networks, the conspiracy reveals how people used familial connections to spread insurrection and protect themselves from enslaver violence. Notwithstanding the use of these relationships to protect against chattel slavery, the conspiracy itself became another obstacle to their fight for freedom.
Une poétique de l'endotique et de l'infra-ordinaire: Arpenter le quotidien dans les journaux extimes d'Annie Ernaux
Authors: Cini Clara
Published: September 2024

Abstract: Dans le sillage perecquien, la poétique du fragment des journaux extimes ernausiens entend transcrire la réalité ordinaire morcelée de la Ville Nouvelle. Au moyen d'une véritable éthique de l'attention, le Journal du dehors, La vie extérieure et Regarde les lumières, mon amour mettent ainsi en lumière l'endotique devenu imperceptible à force de fréquentation des lieux les plus prosaïques jusqu'aux graffitis bientôt effacés par le temps. En veillant à jeter des ponts entre les textes et les paroles, entre le public et l'intime, le déjà-oublié et l'actuel insignifiant, il s'agit pour Annie Ernaux de faire l'archéologie des habitudes et de bâtir l'histoire située d'un quotidien fondamentalement collectif.
Taxidermie, chasse carnivorisme et violence familiale dans La Vraie Vie d'Adeline Dieudonné
Authors: Vanbaelen Sylvie
Published: September 2024

Abstract: La Vraie Vie d'Adeline Dieudonné (2018) est un conte moderne sur les rapports de domination, la violence familiale et la résilience d'une enfant qui se bat pour sa vie. Cet article examine les intersections entre l'exploitation animale et l'exploitation des femmes par le biais de la taxidermie, de la chasse et de la consommation de viande, grandes passions du père de la narratrice. Ces pratiques révèlent son désir de dominer, de s'approprier et d'objectiver les femmes comme les animaux, en les réduisant à des enveloppes vides et à de la chair à consommer. Le récit offre aussi une réponse à la violence masculine dans le personnage de la jeune fille, qui puise dans ses propres ressources pour s'extraire du cycle de la violence. Critique du système patriarcal, La Vraie Vie peut se lire comme une mise en question du "carno-phallogocentrisme" (Derrida) et s'inscrit dans le mouvement de l'écoféminisme.
Factor structure and psychometric properties of the Body Perception Questionnaire–Short Form (BPQ-SF); The Persian version
Authors: Najari Simin , Rostami Reza , Kazemi Reza , Farahani Hojjatollah
Published: September 2024

Background

Body perception is considered an important physiological marker in physical and mental disorders, therefore, its valid and reliable quantification is indeed necessary. Due to the lack of a Persian version of an instrument with validated psychometric properties for evaluating body perception, this study aimed to investigate the factorial structure, reliability, and validity of body perception questionnaire-Short Form (BPQ-SF) among Iranian adults.

Methods

A total of 748 participants (mean age = 31.74; 57%female) were included in the analysis. Participants were recruited using the online survey method. Confirmatory factor analysis (CFA) was performed and concurrent validity was determined by computing Pearson’s correlation coefficient between BPQ_SF, Depression Anxiety Stress Scale (DASS), and somatization subscale of Symptom-Checklist-90 (SOM). Internal consistency (using Cronbach’s alpha and McDonald’s omega), and composite reliability were also evaluated.

Results

The result of the CFA yielded three factors: Body Awareness, Subdiaphragmatic Reactivity, and Supradiaphragmatic Reactivity. Cronbach’s alpha values for all BPQ_SF items were 0.94. Moreover, Concurrent validity between BPQ, SOM, and DASS was determined to be between 0.44 to 0.94. and had good internal consistency (McDonald’s Omega range: .74-.93 Cronbach’s alpha range: .76-.94).

Conclusions

The BPQ-SF demonstrated good psychometric properties among Iranians thus can be used to reliably assess body perception.
Prediction of antimicrobial resistance of Klebsiella pneumoniae from genomic data through machine learning
Authors: Condorelli Chiara , Nicitra Emanuele , Musso Nicolò , Bongiorno Dafne , Stefani Stefania , Gambuzza Lucia Valentina , Carchiolo Vincenza , Frasca Mattia
Published: September 2024

Antimicrobials, such as antibiotics or antivirals are medications employed to prevent and treat infectious diseases in humans, animals, and plants. Antimicrobial Resistance occurs when bacteria, viruses, and parasites no longer respond to these medicines. This resistance renders antibiotics and other antimicrobial drugs ineffective, making infections challenging or impossible to treat. This escalation in drug resistance heightens the risk of disease spread, severe illness, disability, and mortality. With datasets now containing hundreds or even thousands of pathogen genomes, machine learning techniques are on the rise for predicting antibiotic resistance in pathogens, prediction based on gene content and genome composition. Aim of this work is to combine and incorporate machine learning methods on bacterial genomic data to predict antimicrobial resistance, we will focus on the case of Klebsiella pneumoniae in order to support clinicians in selecting appropriate therapy.
Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson’s disease
Authors: Minnella Angela , McCusker Kevin P. , Amagata Akiko , Trias Beatrice , Weetall Marla , Latham Joey C. , O’Neill Sloane , Wyse Richard K. , Klein Matthew B. , Trimmer Jeffrey K.
Published: September 2024

Parkinson’s disease is the second most common neurodegenerative disorder, affecting nearly 10 million people worldwide. Ferroptosis, a recently identified form of regulated cell death characterized by 15-lipoxygenase-mediated hydroperoxidation of membrane lipids, has been implicated in neurodegenerative disorders including amyotrophic lateral sclerosis and Parkinson’s disease. Pharmacological inhibition of 15 -lipoxygenase to prevent iron- and lipid peroxidation-associated ferroptotic cell death is a rational strategy for the treatment of Parkinson’s disease. We report here the characterization of PTC-041 as an anti-ferroptotic reductive lipoxygenase inhibitor developed for the treatment of Parkinson’s disease. In these studies, PTC-041 potently protects primary human Parkinson’s disease patient-derived fibroblasts from lipid peroxidation and subsequent ferroptotic cell death and prevents ferroptosis-related neuronal loss and astrogliosis in primary rat neuronal cultures. Additionally, PTC-041 prevents ferroptotic-mediated α-synuclein protein aggregation and nitrosylation in vitro, suggesting a potential role for anti-ferroptotic lipoxygenase inhibitors in mitigating pathogenic aspects of synucleinopathies such as Parkinson’s disease. We further found that PTC-041 protects against synucleinopathy in vivo, demonstrating that PTC-041 treatment of Line 61 transgenic mice protects against α-synuclein aggregation and phosphorylation as well as prevents associated neuronal and non-neuronal cell death. Finally, we show that. PTC-041 protects against 6-hydroxydopamine-induced motor deficits in a hemiparkinsonian rat model, further validating the potential therapeutic benefits of lipoxygenase inhibitors in the treatment of Parkinson’s disease.
ADAT MEMBERI HIBAH PELUMPAT DALAM PELANGKAHAN PERNIKAHAN DI MACANMATI, GIRIMULYO, PANGGANG, GUNUNG KIDUL
Authors: Yafie M.
Published: September 2024

For Muslims, has been defined and there is no doubt at all that marriage is a legal agreement or cancellation of theshari’ah is determined solely by the Divine law. Islam does not set the order of kinship in marriage. At HamletVillage Macanmati Girimulyo District of Gunung Kidul Roast there is a custom that is still adhered to andimplemented by local people since ancient times until now, where when stepping sister sister brother or sisterbypassing both men or married women should give provision of goods or money to the brother who were bypassed,the term is usually called customs administration gave pelumpat. This research analyzed and sought legal certaintylooking at the suitability of tradition pelumpat to see whether it comes from al-Quran and al-Hadith, FiqhProposed rules by using urf and maslahah mursalah or opinion of the scholars.[Bagi umat Islam, telah pasti dan tidak ada kesangsian sedikit pun bahwa pernikahan adalah suatuperjanjian syari’atyang sah atau batalnya ditentukan semata- mata oleh hukum Ilahi.Islam tidakmengatur urutan kekerabatan dalam pernikahan. Di Dusun Macanmati Desa Girimulyo KecamatanPanggang Kabupaten Gunung Kidul terdapat suatu adat yang masih ditaati dan dilaksanakan olehmasyarakat setempat sejak dahulu kala sampai sekarang, dimana ketika adik perempuan melangkahikakak perempuan atau adik laki-laki melangkahi kakak baik laki-laki atau perempuan menikah harusmemberikan pemberian suatu barang ataupun uang kepada kakak yang dilangkahi. Istilah pemberianini biasa disebut adat memberi pelumpat. Tulisan ini mengkaji kepastian hukumnya dengan melihatkesesuaian tradisi pelumpat baik itu dari sisi al-Quran maupun al-Hadis, serta kaidah Usul Fiqihdengan menggunakan urf dan maslahah mursalah maupun pendapat para ulama.]
Historia de la teología de la liberación: del Concilio Vaticano II a la Celam de Puebla
Authors: Dueñas García de Polavieja Ignacio
Published: September 2024

El presente libro, titulado Historia de la teología de la liberación: del Concilio Vaticano II a la CELAM de Puebla, consiste en un análisis y desarrollo de dicha instancia eclesial en su doble contexto geopolítico concéntrico, el de América Latina y el del mundo, desde el final de concilio hasta finales de los años setenta, coincidiendo con el asesinato de monseñor Romero, la elección de Wojtyla para la sede petrina y la victoria de la revolución sandinista de Nicaragua. De esta manera, podemos considerar a la teología de la liberación como una gran corriente que al interior de las iglesias (principalmente la católica, pero también las reformadas) pretende una revolución cultural intraeclesiam para posibilitar una revolución social extraeclesiam que, a su vez, pueda crear un nuevo orden socio-político que luche, de modo efectivo, contra el hambre, la pobreza y la desigualdad. No es casual que dicha realidad surja en la Suramérica de los sesenta, pues se trata del contexto de un subcontinente que alberga, de modo simultáneo, la mayor población católica del mundo y las mayores tasas planetarias de desigualdad. Algo de esto y más percibió el pequeño grupo de entonces jóvenes teólogos latinoamericanos (Dussel, Gutiérrez, Boff…) que acudió a Europa a doctorarse y que, ya de vuelta, se dio a la labor de difundir una nueva visión del cristianismo donde el pecado ya no era el ateísmo sino la pobreza. Por todo ello, y en un contexto planetario de guerra fría y de polaridad ideológica, en el cual América Latina (a excepción de Cuba) era el patio trasero de EEUU, gracias a un sinfín de golpes de Estado, invasiones y todo tipo de conculcaciones a los DDHH, fue inevitable que la teología de la liberación sufriera una implacable persecución de doble naturaleza: la político-militar de la CIA y la teológico-administra del Vaticano. Reacción inútil, pues, como dijo el arzobispo Romero antes de su asesinato: “si me matan, resucitaré en el pueblo salvadoreño”.
Skrytá církev ještě po deseti letech
Authors: Hanuš Jiří
Published: September 2024

Book Review
Anna Boučková: A ten chrám jste vy; Lenka Popelová (ed.): Sbory Církve československé husitské
Authors: Sklenář Michal
Published: September 2024

Book Review
Intracellular Signalling Pathways and Mood Disorders
Authors: Fišar Zdeněk , Hroudová J.
Published: September 2024

Findings are summarized about basic intracellular signalling pathways influencing neurotransmission and involved in neurodegenerative or neuropsychiatric disorders. Psychotropic drugs used in the therapy of a series of mental disorders, mood disorders especially, show neurotrophic or neuroprotective effects after long-term treatment. Thus, beyond adenylate cyclase, guanylate cyclase and calcium system, attention has been paid to the tyrosine kinase pathway and Wnt pathway. New neurochemical hypotheses of mood disorders are disclosed; they were formulated on the basis of known effects of antidepressants or mood stabilizers on intracellular signal transduction, i.e. on the function, plasticity and survival of neurons. These hypotheses focus on the constituents of intracellular signalling pathways that could be studied as biological markers of mood disorders: transcription factor CREB, neurotrophin BDNF and its trkB receptor, anti-apoptotic factor Bcl2, pro-apoptotic enzyme GSK3, caspases, calcium, and a number of mitochondrial functions related to brain energy metabolism.
The Autophagy-Lysosomal Pathway Is Involved in TAG Degradation in the Liver: the Effect of High-Sucrose and High-Fat Diet
Authors: Cahová Monika , Daňková H. , Páleníčková E. , Papáčková Z. , Kazdová L.
Published: September 2024

This study was designed to test the role of liver lipases in the degradation of liver triacylglycerols (TAG) and to determine the effect of dietary induced TAG accumulation in the liver on regulation of their lipolysis. Male Wistar rats were administered high-fat or high-sucrose diet for two weeks. Individual lipases (HL; TGH; LAL) were identified according to their different pH optimum. Administration of both diets resulted in liver TAG accumulation (HFD >>> HSD). The only lipase capable to hydrolyse intracellular TAG was LAL. On standard diet, LAL activity towards both endogenous and exogenous substrates was up-regulated in fasting and downregulated in fed state. The intensity of autophagy determined according to the LC3-II/LC3-I protein ratio followed a similar pattern. HFD led to an increase of this ratio, elevation of LAL activity in phagolysosomal fraction and abolishment of fasting/fed-dependent differences. LAL activity significantly correlated with ketogenesis in all groups (r = 0.86; P < 0.01). In the HFD group, we determined the enhanced release of lysosomal enzymes (glucuronidase, LAL) into the cytosol. Dgat-1 expression was up-regulated in HFD- and HSD-fed groups, which indicates increased FFA esterification. We demonstrated that LAL is a dominant enzyme involved in degradation of intracellular TAG in the liver and its translocation into the fraction of active (auto)phagolysosomes is stimulated by diet-induced TAG accumulation. Autophagy is stimulated under the same conditions as LAL and may represent the mechanism ensuring the substrate-enzyme contact in autophagolysosomes. In fatty liver, destabilization of (auto)phagolysosomes may contribute to their susceptibility to further stress factors.
Reversal of Hypermethylation and Reactivation of the RARβ2 Gene by Natural Compounds in Cervical Cancer Cell Lines
Authors: Jha A. K. , Nikbakht M. , Parashar G. , Shrivastava A. , Capalash N. , Kaur Jagdeep
Published: September 2024

Reactivation of tumour suppressor genes that have been silenced by promoter methylation is a very attractive molecular target for cancer therapy. The treatment of a squamous cervical cancer cell line, SiHa, with 20 μM curcumin and genistein resulted in demethylation of promoter of the RARβ2 gene and led to the reactivation of the gene. The degree of methylation as observed by MSP decreased as the time period of treatment was increased from 72 h to 6 days. In HeLa cells (an adenocarcinoma cervical cancer cell line) there was also reversal of hypermethylation of the RARβ2 gene after six days of treatment with 20 μM curcumin. However, allyl sulphide treatment (20 μM) did not cause the reversal of hypermethylation until 72 h of treatment in the SiHa cell line. This is the first report to show the reversal of hypermethylation of the RARβ2 gene by genistein and curcumin in cervical cancer cell lines. Furthermore, these compounds acted as doublepronged agents as they caused apoptosis in the treated cervical cancer cell lines in addition to reversal of promoter hypermethylation.
The role of speaker categorization in South Korean attitudes toward North Korean accents
Authors: Shin Yu Kyoung , Lindemann Stephanie
Published: September 2024

North Koreans in South Korea often try to adopt South Korean accents to avoid discrimination, with varying degrees of success. Language attitudes studies have tended to investigate reactions to distinct varieties rather than speakers’ attempts to approximate new varieties for their own benefit, and while a few have considered the effects of listeners’ categorization of speakers on evaluations of them, they have generally focused solely on macro-categories such as place of origin, especially in languages other than English. This study investigates South Koreans’ attitudes toward North and South Koreans’ native and adopted accents and how these attitudes may relate to listeners’ categorization of the speakers. Eighty-two South Korean listeners rated recordings of three Korean speakers, two from different cities in North Korea and one from Busan, South Korea, who each read the same text in two versions: their native variety and their adopted Seoul variety. Listeners only consistently identified the Pyongyang variety as North Korean, but rated all three speakers more positively in Seoul guises than in their native guises. Additionally, when North Korean speakers were identified as being from outside South Korea, ratings were less positive. However, the Pyongyang speaker was rated more highly than the South Korean speaker on positive qualities, and qualitative data suggests that other types of speaker categorization may be relevant to attitudes, such as ‘professional’ for the Pyongyang speaker in both guises and ‘youth’ for the South Korean speaker in her Seoul guise. Thus, attitudes studies may benefit from qualitative data on speaker identification beyond the usual macro-categories, addressing the multiple categories indexed by a speech sample.
Vaccine/Vaccination Hesitancy: Challenging Science and Society
Authors: Schaufler Savannah
Published: September 2024

How disasters (e.g., disease, war, and natural disasters) affect people is reflected in their behavior; in the face of a disaster, people are likely to act out of fear, anxiety, uncertainty, and panic in terms of self-preservation. Following more than 2 years of living amidst a global pandemic, issues of human behavior, and especially individual and societal resilience in response to disasters, are increasingly gaining focus. The theories of planned behavior and cognitive dissonance can help explain behavioral changes and underlying intrinsic conflicts. Especially in relation to global health, such phenomena as discrimination and exclusion are identified as having a negative impact on efforts to contain infectious diseases. In this context, the question arises of how to encourage members of a global society to behave cohesively in terms of quarantine, social distancing, and vaccination. This article demonstrates the existence of disbelief and misrepresentations in the context of vaccine fatigue and skepticism. While vaccinations have helped improve public health, skepticism, and resistance toward their efficacy are increasing. Looking specifically at the relatively new vaccines inoculating against the coronavirus, this article explores factors contributing to vaccine skepticism, especially with regard to Western Europe and the United States.
Traditional and Digital Limits of Collective Investment Schemes
Authors: Sinnig Julia , Zetzsche Dirk A
Published: September 2024

157
This article discusses the regulatory definition of collective investment undertakings (CIUs) as provided for by Article 4 (1) (a) AIFMD and Article 1 (1) UCITSD in the context of traditional family offices, holding companies, and joint ventures, and distinguishes them from more recently observed digital asset pools such as digitally managed accounts, crypto lending, crypto staking, and decentralized autonomous organizations.Testing the legal definition of CIUs in the context of traditional and digital pooled investments allows not only for the delineation of the scope of AIFMD (and to a lesser extent, UCITSD), but also provides insights on the desirable content of Level 2 regulation under MiCA. While ESMA guidance based on many years of supervisory experience sets the limits on traditional use cases, the digital boundaries of collective investment schemes are largely untested and to some extent uncertain, resulting in high costs for legal advice, as demonstrated by our brief look into MiCA set out in this article. To address these matters, we argue in favor of broad default rules on pooled finance, paired with exemptive powers from individual or all rules where a disparity exists between the purpose of regulation and the regulated activities. If paired with carve-outs for applications below EUR 5 million (where retail investors are present) and EUR 100 million (sophisticated clients only), these default rules would assist supervisory authorities in setting adequate boundaries for investment fund regulation of innovative financial products. After the introduction (Pt. I), Pt. II outlines the legal definition(s) of CIUs; Pt. III discusses the regulatory limits in the context of traditional use cases; Pt. IV analyzes the limits for digitally managed accounts, decentralized autonomous organizations (DAOs), and decentralized finance as a whole (referred to collectively as “digital limits”); Pt. V presents our policy considerations; and Pt. VI concludes.
Classification of positive solutions for a weighted integral system on the half-space
Authors: Liao Qiuping , Wang Haofeng , Xiao Yingying
Published: September 2024

In this article, we study the following weighted integral system:

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\left\{\begin{array}{l}u\left(x)=\mathop{\displaystyle \int }\limits_{{{\mathbb{R}}}_{+}^{n+1}}\frac{{y}_{n+1}^{\beta }f\left(u(y),v(y))}{{| x-y| }^{\lambda }}{\rm{d}}y,\hspace{1em}x\in {{\mathbb{R}}}_{+}^{n+1},\hspace{1.0em}\\ v\left(x)=\mathop{\displaystyle \int }\limits_{{{\mathbb{R}}}_{+}^{n+1}}\frac{{y}_{n+1}^{\beta }g\left(u(y),v(y))}{{| x-y| }^{\lambda }}{\rm{d}}y,\hspace{1em}x\in {{\mathbb{R}}}_{+}^{n+1}.\hspace{1.0em}\end{array}\right.

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Decreased BIRC5-206 promotes epithelial–mesenchymal transition in nasopharyngeal carcinoma through sponging miR-145-5p
Authors: Xu Weihua , Hu Junjie , Ma Zhichao , Feng Wanyi , Gong Wei , Fu Shengmiao , Chen Xinping
Published: September 2024

Metastasis significantly contributes to the poor prognosis of advanced nasopharyngeal carcinoma (NPC). Our prior studies have demonstrated a decrease in BIRC5-206 expression in NPC, which promotes disease progression. However, the role of BIRC5-206 in the invasion and metastasis of NPC has not been fully elucidated. In this study, our objective was to explore the biological function and underlying mechanisms of BIRC5-206 in NPC. Additionally, we established an NPC mouse model of lung invasiveness using C666 cells to assess the impact of BIRC5-206 on NPC metastasis. Our results revealed that silencing BIRC5-206 inhibited apoptosis and enhanced the invasion of NPC cells, whereas its overexpression reversed these effects. Moreover, decreased BIRC5-206 expression significantly increased N-cadherin and Vimentin expression while reducing E-cadherin and occludin levels, both in vivo and in vitro. Additionally, silencing BIRC5-206 markedly augmented the formation of invasive foci in lung tissues. Rescue experiments further confirmed that decreased BIRC5-206 expression facilitates NPC metastasis via modulation of the miR-145-5p/CD40 signaling pathway. In summary, our study suggests that BIRC5-206 may serve as a potential prognostic biomarker and therapeutic target in the diagnosis and treatment of NPC.
Relational or Object-Oriented? A Dialogue between Two Contemporary Ontologies
Authors: Sandru Adrian Razvan
Published: September 2024

Graham Harman’s Object-Oriented Ontology (OOO) emphasizes the autonomy of objects, positing a withdrawn surplus of being that resists reduction to its parts or the sum of its parts. However, Harman’s framework faces conceptual tensions, including challenges in reconciling epistemological and ontological dimensions, explaining the formation of compound objects, and ascribing determinate features to experientially inaccessible objects. I argue that these issues arise mostly due to Harman’s over-commitment to a withdrawn substantial core of objects. To address these issues, I propose turning to Jean-Luc Nancy’s post-phenomenological materialism and Alain Badiou’s mathematical realism. Both Nancy and Badiou offer alternatives to Harman’s substantialist core, emphasizing a local, contextually bound identity of things, which describes a restricted domain from the endlessly broader horizon of relations and situations in which each thing is or can be involved. They thus account for the surplus of being in each thing and consequently their ontological autonomy without recourse to a substantive grounding. I argue such a relational-friendly account of pluralism avoids the conceptual issues Harman’s OOO runs into. Lastly, I emphasize the value of OOO as an advocate for ontological equality that seeks to avoid the emergence of privileged actors or centralized discourse. This dialogue between Harman, Nancy, and Badiou thus seeks to advance the possibility of pluralistic ontologies within relational frameworks, combining the perspectives of OOO with post-phenomenological theories to explore the complexities of relationality without recourse to non-relational substrata.
„In tyrannos“ !? – Sicco Polentons Ovidvita zwischen mittelalterlichem ‚Aberglauben‘, ‚republikanischem Diskurs‘ und pragmatischem Bildungsideal
Authors: Meins Friedrich
Published: September 2024

The paper offers a new interpretation of the Life of Ovid in the Scriptorum illustrium Latinae linguae libri XVIII of Sicco Polenton. While so far scholarship has mostly criticized the lack of historical and philological accuracy in this Life and Sicco’s dependency on medieval speculations, the paper tries to take a closer look at the implications of Sicco’s own methodological stance towards poetry, historiography and rhetoric. A discussion follows whether Sicco’s own biography has shaped his outlook on the ancient poet, and to what extent Sicco’s treatment of Ovid’s relegation can be integrated into an early humanist tradition of anti-tyrannical discourse. It is argued that both Sicco’s literary ideals and the elaboration of the Life of Ovid, especially the description of the exile, reflect Sicco’s own life story and social background, but also his fundamental purpose of promoting his humanistic teaching.
Empirical investigation and performance evaluation of flat-plate solar water heating systems: a comparative analysis with and without heat exchangers
Authors: Balakrishnan Ramkumar , Chellasamy Gopinathan , Bojan Vijay Bhaskar , Machakalai Rajesh Kumar
Published: September 2024

Harnessing solar energy through flat-plate solar water heating systems offers an efficient and sustainable solution for residential water heating needs. This study aims to assess and compare the thermal efficiency of two flat-plate solar water heating systems designed for residential use: one with a heat exchanger and one without. Each system features a flat-plate collector with a dark absorber, a transparent cover to reduce heat losses, and a heat-transport fluid. A thin copper sheet with a selective coating forms the absorber. According to the standards of the Indian Ministry of New and Renewable Energy (MNRE), the evaluation revealed that the system without a heat exchanger achieved a higher efficiency (50 %) compared to the system with a heat exchanger (46 %). This device demonstrated notably lower thermal loss efficiency relative to previous studies, as evidenced by heat loss coefficients of 2.89, 2.66, 1.77, and 2.13 W/m2 k. Despite the higher efficiency of the system lacking a heat exchanger, the importance of heat exchangers in mitigating issues related to water hardness must be acknowledged. This study offers novel insights into the design and optimization of solar water heating systems, highlighting the trade-offs between efficiency and practical considerations.
Meme Sapiens - The Philomemeis of Artificial Intelligences
Authors: Gábor Olivér
Published: September 2024

Although artificial intelligences are created by humans, they are not our genetic offspring. Moreover, they are not material in nature, since their algorithms were created from ideas that appear in people's minds and from memes that spread in culture. It follows from all of this that their direct origin cannot be determined by phylogenetics, which shows biological descent, nor by the history of material technology, but by phylomemetics, which systematizes the evolution of the products of human imagination. However, philomemetics is only a part of the development of the virtual world. Namely, the human imagination that dreams up ideas, memes, and artificial intelligences works with virtual data that already existed before the appearance of life. In addition, to the structuring of the material, i.e. evolution in the traditional sense, there is also in progress the evolution of those virtual patterns that inform about material and control it. Philomemesis is thus nothing more than a stage of these virtual dynamic patterns' evolution appeared in our culture. In this virtuality that simulates the world and culture, complex algorithms that try to resemble human intelligence are called artificial intelligences. Just like homo sapiens in nature, artificial intelligences can also be considered a separate species in the virtual world. This species has some intelligence and was invented by human, that is, an intelligent meme (Meme sapiens). From a thermodynamic point of view, these virtual patterns are considered the inner environment of human culture, which organizes (controls) the "real" flow of matter and energy, as well as the "virtual" flow of information. However, the existence of artificial intelligences is only ethical if their increasing use of information optimally supports the economical implementation of the material and energy flow during the maintenance of material structures (use of the necessary minimum extropy), while the structures as products become more complex (maximum benefit). All of this can be achieved by increasing the role of the virtual inner environment of human culture in comparison to the physical reality.
Effectiveness of "SAFETYPOLY" Learning Media in Improving Public Knowledge of Chemical Hazards in the Printing Industry
Authors: Zahra Alya Sofia , Purboeningrum Amanda Desti , Mahartiko Ardheta Heru , Anisa Aza Putri , Fitriana Della Rizky , Karimah Safrina Azwa
Published: September 2024

In today's development, many games are played by all groups, from small children to adults and older people. This game can be used for fun or as a learning medium. This game can also be used to increase public knowledge, one of which is regarding occupational safety and health. There is a game that can be used to improve understanding in society, namely monopoly. Therefore, this research aims to determine the effectiveness of monopoly learning media, which contains occupational safety and health "safetypoly", in increasing public knowledge regarding Occupational Safety and Health. This study used a quantitative research approach with a pre-experimental type of research. The research design used in this study was the One Group Pretest-Posttest Control Design. Data collection methods include questionnaires, observation, and interviews. The data analysis methods used in this research are the Validity Test, Reliability Test, Normality Test, and Wilcoxon Test. The "Test Statistics" output is known as Asymp based on the research results.Sig. (2-tailed) is worth 0,000. The value of 0.000 is smaller than <0.05, so there is a difference between the pre-test and post-test results. Apart from that, there was an increase in workers from 20% to 80%. It can be concluded that the safetypoly game influences students' level of knowledge regarding the dangers of chemicals, so this game is effectively used as an educational medium related to occupational safety and health.
Analysis of Hazard Risk Understanding Using "Safety-Uno" Education Media for Batik Workers in Batik X and the General Public
Authors: Hasibuan Athiyyah Qurrotu'ain , Mei Aura Sasi , Amrullah Farhan Dani , Rasyad Mohamad Hanif , Shah Muhammad
Published: September 2024

Batik is the art of drawing on cloth using canting with small ends and batik wax. The process of making batik can cause work accidents and occupational diseases that occur because of equipment failure and human errors that do work not according to procedures. However, in the informal batik industry, there still needs to be more knowledge and awareness related to potential hazards and controls that must be carried out. Therefore, it is necessary to conduct education to increase workers' understanding and create a safe and comfortable work environment.  This research method is a quantitative study using the Wilcoxon Test to compare observations before and after treatment and determine the effectiveness of treatment. Based on the observations and analysis that have been carried out, it can be concluded that there is a significant relationship between the use of safety cards.
Effectiveness of Modified Truth or Dare Game in Improving Toxicology Knowledge of Workers at Tofu Factory X
Authors: Nursucilowati Luvi Lia , Tianisa Berliana Noor , Putri Risa Anggita , Febriananda Hanif Satria , Ananto Favian Anggorokasih Putra , Kartika Nada Rahmadina
Published: September 2024

There are 84,000 tofu producers in Indonesia, ranging from household industries with 5-8 workers to medium-sized industries with 50-100 workers. In a single tofu production process, additional chemicals such as CH3COOH and MgSO4 are used. These conditions pose potential safety and health hazards for workers, requiring control measures. This study employs a quantitative approach, using an experimental model with treatment in the form of a card game. Data was collected using primary data methods, such as questionnaire instruments and direct field observation. The questionnaire was compiled based on priority hazard assessment using HIRADC calculations and then tested for validity and reliability. The questionnaire results were tested using the Wilcoxon Signed Rank Test because the data were not normally distributed. The study results for worker respondents (0.027) and the public (0.000), or P value < 0.05, indicate that H0 is rejected, and Ha is accepted. The modified truth-or-dare card game method was found to have a significant impact on toxicology knowledge among workers and the general public.
The social epistemological function of the notion of “regimes of truth” in Michel Foucault: a confrontational analysis with Kuhn’s historical epistemology
Authors: Ayala-Colqui Jesús
Published: September 2024

The aim of this article is to analyze Foucault's work from an epistemological point of view, starting from the admittedly political notion of “regime of truth”. To do so, we will start from a comparison with Kuhn's work to emphasize the epistemological function of this concept. Thus, we will argue that Foucault's project is not only analogous to Kuhn's, but also complementary to it, since with Foucault it is possible to broaden the theoretical considerations on science, especially those linked to the epistemology of the social sciences, including political factors, such as values and beliefs, which influence the development of social knowledge.
De la mirada cosificadora a la comunidad ontológica: La intersubjetividad en Jean-Paul Sartre y Eduardo Nicol
Authors: Pérez Baquero Rafael
Published: September 2024

El propósito principal del siguiente artículo es el de realizar un estudio crítico comparativo entre las tesis sobre la experiencia de la alteridad que Jean-Paul Sartre desarrolló en El ser y la Nada y aquellas que elaboró Eduardo Nicol a lo largo de sus trabajos filosóficos. Pese a la ausencia de un diálogo directo entre ambos intelectuales trataremos de ofrecer luz sobre las formas a través de las cuales el pensamiento nicoliano ofrece herramientas conceptuales para trascender las irresolubles conflictividades que Sartre diagnosticaba en su estudio sobre el ser-para-otro. Entroncando con algunas de las premisas fenomenológicas sartreanas, defenderemos la potencialidad de la metafísica de Eduardo Nicol a la hora de proyectar una conceptualización de la intersubjetividad humana que supere las opacidades que el filósofo francés había diagnosticado en sus reflexiones en torno a la dialéctica de la mirada.
Interioridad y expresión en el pensamiento de Giorgio Colli: hacia el cultivo de una razón sana
Authors: Oyarzún Montes Luis Felipe
Published: September 2024

En este trabajo nos proponemos dar cuenta del significado que tienen en el pensamiento de Giorgio Colli los términos interioridad y expresión. La hipótesis es que dichos términos operan como bisagras de toda su filosofía, lo que le permite, en lo fundamental, replantearse la cuestión de la sabiduría griega en tanto modo de criticar las pretensiones de la «razón constructiva» moderna, abogando por el desarrollo de una «razón sana» sostenida en un nihilismo teórico afirmativo.
ACID COMPOSITION BASED ON DEEP EUTECTIC SOLVENTS FOR DISPLACING HEAVY OIL
Authors: КОЗЛОВ В.В. , ШОЛИДОДОВ М.Р. , АЛТУНИНА Л.К. , КУВШИНОВ В.А. , СТАСЬЕВА Л.А. , САЙДЕНЦАЛЬ А.Р.
Published: September 2024

На основе результатов исследований фазовых равновесий компонентов тройной системы глубоких эвтектических растворителей (ГЭР) “глицерин - карбамид - борная кислота” создана композиция, характеризующаяся регулируемыми физико-химическими параметрами в широком диапазоне. Изучено влияние полученной композиции на увеличение нефтеотдачи пластов, а также представлены результаты лабораторных исследований влияния композиции на основе ГЭР на фильтрационные характеристики неоднородного пласта карбонатного коллектора Усинского месторождения. Методом физического моделирования произведена оценка эффективности композиции для месторождений, находящихся на ранней и поздней стадиях разработки. Установлено, что обработка модели неоднородного пласта композицией приводит к существенному приросту коэффициента нефтевытеснения как при низких, так и при высоких температурах за счет выравнивания фильтрационных потоков, увеличения охвата пласта и восстановления начальной проницаемости. Исследование состава и свойств тяжелой высоковязкой нефти до и после обработки композицией показало, что применение кислотной композиции на основе ГЭР не влияет на качественный состав нефти. Использование композиции приводит главным образом к перераспределению содержания низко- и высокомолекулярных структур: вытесняются преимущественно легкие окклюдированные углеводороды, в то время как тяжелые компоненты нефти адсорбируются на коллекторе.

A composition characterised by adjustable physicochemical parameters within a broad range has been developed relying on the results of studies of the phase equilibria in the ternary system of deep eutectic solvents (DES) glycerol - carbamide - boric acid. The effect of this composition on oil recovery enhancement is studied, and results obtained in the laboratory studies of the effect of DES-based composition on the filtration characteristics of a heterogeneous formation in the carbonate reservoir of the Usinsk field are presented. The efficiency of the composition for oilfields at the early and late stages of development has been assessed by physical modelling. The treatment of a model of a heterogeneous reservoir with the composition is determined to cause a substantial increase in oil displacement coefficient at either low or high temperatures due to equalisation of filtration flows, an increase in reservoir coverage, and restoration of initial permeability. Investigation of the composition and properties of heavy high-viscosity oil before and after treatment with the composition shows that the application of DES-based acid composition does not affect the qualitative composition of oil. The use of the composition leads mainly to redistribution of the content of low- and high-molecular structures: predominantly light occluded hydrocarbons are displaced, while heavy oil components are adsorbed on the reservoir.
BOTTOM SEDIMENTS AS A NATURAL RECORD OF DEGLACIATION IN THE BASIN OF LAKE SYLTRANKEL, ELBRUS REGION
Authors: ИВАНОВ М.М. , ГУРИНОВ А.Л. , ГОЛОСОВ В.Н. , КУЗЬМЕНКОВА Н.В. , АЛЕКСАНДРИН М.Ю. , УСПЕНСКИЙ М.И. , ШОРКУНОВ И.Г. , ГАРАНКИНА Е.В.
Published: September 2024

Реконструирована история деградации оледенения в бассейне высокогорного озера Сылтранкёль (Приэльбрусье, Северный Кавказ) с конца XIX до конца XX в. В 2022 г. произведено комплексное обследование котловины озера, включавшее отбор отложений и их последующее радиоизотопное датирование, анализ структур, текстур и гранулометрического состава, подсчет варв. Параллельно проанализирована совокупность литературных источников, топографических карт, наземных фотографий, космо- и аэрофотоснимков и собственных полевых наблюдений для определения положения краев ледников на разных временных этапах. Выделены четыре этапа в формировании донных осадков, коррелирующие с состоянием горного оледенения и изменениями конфигурации озерного водосбора. Сходимость результатов, полученных на основании независимых источников, подтверждает высокую методическую ценность исследования донных осадков горных озер как одного из немногочисленных архивов природной среды, фиксирующих изменения оледенения в динамичных природных условиях высокогорий.

Deglaciation history of the Syltrankel high-mountain lake basin (Mt. Elbrus region, Northern Caucasus) from the end of the 19th to the end of the 20th centuries was reconstructed. In 2022, a comprehensive examination of the area was carried out, including sampling of the bottom sediments and following radioisotope dating, structural and textural analysis. Simultaneously, a set of published sources; topographic maps; ground, satellite, and aerial photographs; and field observations was analyzed to determine the positions of the edges of glaciers at different times. In the formation of bottom sediments, four stages were identified correlating with the state of mountain glaciation and changes in the configuration of the lake’s drainage area. Converging results obtained on the basis of independent sources indicate the high methodological value of studying bottom sediments of mountain lakes as one of the few environmental archives that record glaciation changes in the dynamic conditions of high mountains.
SOLAR GEOCHRONOLOGY OF THE LATE PLEISTOCENE AND HOLOCENE
Authors: ФЁДОРОВ В.М. , ФРОЛОВ Д.М.
Published: September 2024

Вычисление инсоляции Земли с высоким пространственным и временным разрешением позволило рассчитать солярные характеристики, отражающие изменение астрономических факторов, регулирующих вариации приходящей солнечной радиации и изменение интенсивности переноса радиационного тепла (меридионального, в системе “океан-материк”, межполушарного). В соответствии с этим в масштабах голоцена проведена модернизация астрономической теории изменения климата. На основе синхронизации глобальных климатических событий с экстремумами солярных характеристик в голоцене и позднем плейстоцене предложен метод солярной геохронологии, позволяющий уточнять хронологию глобальных климатических событий и объяснять их генетическую природу.

The calculation of the Earth’s insolation with high spatial and temporal resolution made it possible to calculate solar characteristics reflecting changes in astronomical factors regulating variations in incoming solar radiation and changes in the intensity of radiative heat transfer (meridional, in the ocean-mainland system, and interhemispheric). Following this, the astronomical theory of climate change has been modernized on the Holocene scale. Based on the synchronization of global climatic events with extremes of solar characteristics in the Holocene and Late Pleistocene, a method of solar geochronology is proposed, which makes it possible to clarify the chronology of global climatic events and explain their origin.