bluuebunny/crossref_metadata_2025 huggingface dataset:
Academic Librarians’ Perception of Work-Life Balance and Self-Management Skills
Authors: Durodolu Oluwole Olumide , Mojapelo Samuel Maredi
Published: December 2023

This study focuses on the work-life balance of librarians and considers significant factors that could influence this balance, such as the formulation of policies, workplace support, workload, financial assistance, work expectations and work satisfaction. This research adopted a positivist research paradigm in which a questionnaire was used as an instrument of data collection. The survey targeted Kenneth Dike Library of the University of Ibadan, which is the first university library in Nigeria. With 103 members of staff, the sample size was purposively selected. The reliability of the research instrument was tested by using Cronbach’s alpha, which yielded an overall reliability value of 0.91. The study revealed the following: (1) Work-life policy documents were not at the disposal of the librarians because they were not implemented and no good programmes that could enrich the work-life balance of librarians exist. (2) Librarians want to receive fair treatment and respect among their colleagues and be recognised when they take the initiative on their job. It is crucial to communicate the policy to librarians, whether it is included in the employee’s handbook or not; it is vital to organise a seminar to alert library staff to the importance of the policy, the benefits it provides, and its implementation procedure.
Investigating Small-scale Farmers and Barriers to Entry in Cannabis Cultivation in South Africa
Authors: Dube Itumeleng , Makola Zamandlovu S , Ntoyanto Nonceba , Manamela Dipakiso
Published: December 2023

The legalisation of the prodigal green crop has left the most vulnerable small-scale cannabis farmers high and dry. In 2018 the South African constitutional court legalised the use of cannabis for personal and medical use. The 2018 regulations on cannabis were welcomed and a new lifeline in the eradication of poverty. However, in the haste to join the global urgency in cultivating cannabis, small-scale farmers were left behind and prevented in the bid of the green-gold rush. The cannabis legislation and laws that were created to enable South Africans to participate in the lucrative cannabis market has done the opposite and has crafted barriers of entry. Using a desktop study, this article explores how the 2018 regulations on cannabis cultivation prevent small-scale farmers in participating in the l market in South Africa. The aim of this paper is to highlight the challenges that small-scale cannabis farmers face in South Africa and how their participation in the newly opened market would benefit the communities they live and operate in. The main findings of the research indicate the challenges for small-scale farmers of no support system and transformational issues persist even after the 24 years of democracy in South Africa.
Physical Properties of ZnO-NPs Induced by the Thermal Annealing of Hydrozincite Derived from Adansonia Digitata Leaves Extract
Authors: Ngom Ibrahima , Fall Adama , Sarr Samba , Ndiaye Baye Modou , Mbodj Seynabou , Bucher Remy , Ngom Balla Diop
Published: December 2023

In this study, we investigated the effects of the annealing temperatures on the physical properties of zinc oxide nanoparticles produced by the decomposition of the hydrozincite obtained from Adansonia digitata leaves. The results of the X-ray diffraction revealed the formation of well-crystallised hexagonal zinc oxide with an average crystallite size of 11.80 nm, 11.90 nm, 11.97 nm and 15.28 nm for the samples annealed at 400 °C, 500 °C, 600 °C and 700 °C, respectively. The crystallite size of the hydrozincite constituting the unannealed sample was 22 nm. In the spectra of the Fourier transform infrared spectroscopy, the appearance of the peaks at 520 cm-1 for all synthesised materials confirms the formation of pure wurtzite zinc oxide. The band gap determined from diffuse reflectance ultraviolet-visible spectroscopy was found to be 3.19 eV, 3.21 eV, 3.23 eV and 3.24 eV for the samples annealed at 400 °C, 500 °C, 600 °C and 700 °C, respectively. These values increase with the annealing temperature and are still lower than the band gap of pure bulk zinc oxide (3.3 eV) owing to the structural defects as confirmed by the broad emission bands in the visible depicted from the photoluminescence analysis.
The U.S. Constitution is Not a Code: Unraveling the Idea and the Meaning of Substantive Due Process
Authors: Grossi Simona
Published: December 2023

This Article delves into the nuanced meaning of substantive due process by tracing its historical and contemporary contexts. Beginning with the exploration of pre-ratification state constitutions, the debates surrounding ratification, and early Court views on the Constitution’s nature (perceived not as a code

but an enduring collection of principles), the study then addresses the role and meaning of stare decisis as positive of history and tradition, and the role of judicial decision-making in our system starting from Marbury v. Madison. The Article concludes by linking substantive due process to universally recognized fundamental rights, emphasizing that our Constitution’s true intent is to safeguard these inalienable rights in service of our system and “We the People.”
Secrecy and Transparency in Substantive Due Process Litigation
Authors: Benham Dustin B.
Published: December 2023

A few years before the recomposed Court rejected abortion rights in Dobbs, it sustained several healthcare providers’ challenge to Louisiana abortion restrictions in June Medical. History will remember that 5–4 decision mostly as one of the last major cases to interpret and apply the Casey framework.

But in the little-noticed background of the June Medical litigation, a significant dispute over sealed court records boiled over. On one side, plaintiff physicians sought anonymity and confidentiality in light of potential threats to their physical safety and patient privacy. On the other side, Louisiana asserted the public’s longstanding right to access court records and its own right to include information from June Medical companion cases in its Supreme Court briefing. Ultimately, the Fifth Circuit agreed with Louisiana, vacating the sealing order.

June Medical evokes a larger dispute simmering in federal and state courts over public access to litigation information. Modern commerce and contemporary life generate an unprecedented volume of data. American civil discovery provides litigants with tools to discover and collect much of it. And courts have long recognized the public’s First Amendment and common law rights to inspect and copy public court files. Moreover, the internet and advent of electronic filing have transformed once obscure paper court files into easily accessible databases.

Proponents of expanded sealing and secrecy contend that this status quo threatens litigants’ privacy and intellectual property. Proponents of more transparency posit that public access to the evidence underlying court action is essential to the integrity and proper functioning of the judiciary, as well as to public health and safety.

This Article examines a largely unexplored angle of this debate: How should courts treat the unique privacy interests of litigants asserting substantive due process claims in the context of the public’s right to access litigation information? Part II explains the public’s court-access rights. Part III first considers whether forced identity revelation might infringe substantive due process rights. After concluding that infringement is possible, but recognizing that courts will often avoid the constitutional privacy questions posed by these scenarios, Part III goes on to consider the use and effects of subconstitutional privacy and access principles in rights cases where parties seek to proceed pseudonymously.
The control of growth and development in the reduction of anemia in Peru
Authors:   Universidad Continental. Cusco, Perú, Castro Mayta Evelyn Gabriela
Published: December 2023

Introduction: Anemia is a public health problem that mainly affects children under five years of age. Objective: Determine the impact of growth and development control (CRED) in reducing anemia in children under five years of age in Peru considering the analysis of the Demographic and Family Health Survey (ENDES) 2021. Method: Analytical and cross-sectional study with a secondary analysis of data from the 2021 ENDES survey. Results: 31.4% of children under five years of age had anemia, where 38.3% corresponded to rural areas; 34.0%, male children; 56.9%, under one year old; 38.5% were mothers with primary education and 40.8% belonged to the index of the poorest, showing statistically significant differences. In relation to the CRED, it was evident that 32.4% of children who did undergo a CRED and 30.2% of children who did not had anemia. Regarding the place where it was carried out, it was observed that 32.4% of children who were cared for in a health facility and 32.9% of children who were cared for by the nurse had anemia. Conclusion: Anemia is a public health problem that is present and conditioned by various factors and determinants. During the pandemic, the impact of CRED in reducing anemia was ambiguous, so there are assumptions about whether the interventions are having the desired and expected impact.
Influence of the Ptolemy-Pliny-Strabo Fault Zone in Bozburun Peninsula (southwest Türkiye): Evidence from structural data and focal mechanism solutions
Authors: SEYİTOĞLU Gürol , KAYPAK Bülent , TANÜLKÜ Edanur , KARABIYIKOĞLU Tolga , KOCA Begüm
Published: December 2023

Structural data obtained from fault surfaces in the Bozburun Peninsula, southwest Türkiye indicate that the previously known active normal faults are indeed strike-slip structures. The configuration of left- and right-lateral strike-slip segments and lineaments observed from high-resolution satellite images, plus the evaluation of available focal mechanism solutions of the earthquakes having less than 30 km depth around Bozburun Peninsula, show that the study area is under influence of the left-lateral Ptolemy-Pliny-Strabo Fault Zone.
ADVERSARIAL LEARNING IN IMAGE SEGMENTATION
Authors: Гайнетдинов А.Ф.
Published: December 2023

В статье рассматриваются методы нейронных сетей для сегментации изображений транспортных средств. Метод. Использовалось 3 нейронных сети: сверточная нейронная сеть (CNN), специализированные глубокие сверточные сети (TDCNN), сеть CowOut/CowMix, а также генеративно-состязательная сеть (GAN). В качестве объектов исследования были выбраны изображения автомобилей, автобусов, мотоциклов и велосипедов. Для обучения использовали разное количество изображений из выборки: от 30 до 300. Результаты работы.Все испытуемые модели показывают высокий процент эффективности. Значения показателей значительно увеличиваются с ростом количества данных для обучения во всех случаях. Минимальные результаты наблюдались при использовании типичной модели CNN и других нейронных сетей, тогда как генеративно-состязательная была наиболее результативной. В конечном итоге, показатели для классов «автомобиль», «автобус», «велосипед» и «мотоцикл» соответственно: IoU = 70,9%, 71,2%, 65,7%, 70,4%; dice = 96,0%, 97,3%, 94,7%, 96,7%; precision = 85,2%, 85,4%, 78,9%, 82,4%; specificity = 79,5%, 79,2%, 68,9%, 75,2%; accuracy = 80,3%, 80,3%, 75,3%, 79,7%. Выводы. Таким образом, применение состязательной сети является эффективным методом сегментации изображений транспортных средств, особенно автомобилей и автобосув, что может быть использовано в машинном зрении.

This article discusses different methods of vehicle image segmentation based on neural network. A total of four neural networks were employed: the Convolutional Neural Network (CNN), the Tailored Deep Convolutional Neural Network (TDCNN), the CowOut/CowMix Network, and the Generative Adversarial Network (GAN). The dataset contained images of cars, buses, motorcycles and bicycles. The training datasets comprised 30 to 300 images. All models under testing show high efficiency. As the training data size increased, the values of the indicators also increased significantly; this is true for all cases. The typical CNN model and other neural networks performed poorer than the GAN model, which proved to be the most effective. For the datasets “car”, “bus”, “bicycle” and “motorcycle”, the following indicators were obtained: IoU = 70.9%, 71.2%, 65.7%, and 70.4%; dice = 96.0%, 97.3%, 94.7%, and 96.7%; precision = 85.2%, 85.4%, 78.9%, and 82.4%; specificity = 79.5%, 79.2%, 68.9%, and 75.2%; accuracy = 80.3%, 80.3%, 75.3%, and 79.7%, respectively. Based on the research, adversarial training is an effective method to segment out vehicles, especially cars and trucks, which can be used in machine vision.
VALIDATION OF THE METHODOLOGY FOR QUANTITATIVE DETERMINATION OF GLYCERIDES OF SEA BUCKTHORN OIL
Authors: Горемыкина Н.В. , Верещагин А.Л. , Кошелев Ю.А. , Першин Н.С.
Published: December 2023

В статье представлены результаты валидации предложенной методики количественного определения глицеридов облепихового масла методом высокотемпературной газовой хроматографии. Валидация методики количественного определения трипальмитина и трипальмитолеина проводилась по следующим характеристикам: стабильность испытуемых растворов; специфичность; правильность, доверительный интервал; линейность, коэффициент корреляции; прецизионность; повторяемость и межлабораторная воспроизводимость.

The paper presents the results of validation of the proposed method of quantitative determination of sea buckthorn oil glycerides by high-temperature gas chromatography. Validation of the method of quantitative determination of tripalmitin and tripalmitolein was carried out according to the following characteristics: stability of test solutions; specificity; correctness, confidence interval; linearity, correlation coefficient; precision; repeatability and interlaboratory reproducibility.
STUDY OF THE INFLUENCE OF THE TYPE OF SUPPORT ON THE ACTIVITY, SELECTIVITY AND STABILITY OF THE CATALYTIC SYSTEM IN THE REACTIONS OF REDUCTIVE HYDROGENOLYSIS OF THE GB PRODUCT
Authors: Злочевская П.В. , Компаниец И.И. , Петров Е.А.
Published: December 2023

Гексанитрогексаазаизовюрцитан (CL-20) - мощнейшее взрывчатое вещество нового поколения. Высокие значения плотности (ρ = 2,04 г/см3) и энтальпии образования (DНоf =377,410 ∙103Дж∙моль-1) обуславливают уникальные энергетические характеристики продукта, и делают его, несомненно, привлекательным компонентом для создания различных рецептур и изделий. В настоящее время проводятся интенсивные разработки по применению CL-20 в рецептурах энергетически наполненных полимерных композициях – смесевых ракетных твердых топлив (СРТТ). Установлено, что использование ГАВа в составе СРТТ значительно повышает баллистическую эффективность топлива. Однако его широкому применению в СРТТ препятствует высокая стоимость. В синтезе CL-20 двухстадийный гидрогенолиз 2,4,6,8,10,12-гексабензилгексаазаизовюрцитана (ГБ) проходит с использованием дорогостоящего палладиевого катализатора Pd/сибунит, который подвержен быстрой дезактивации. Одним из основных инструментов оптимизации – варьирование свойств углеродного носителя. Наноалмаз – высокопрочный носитель с уникальной величиной удельной поверхности.

Hexanitrohexaazaisowurtzitane (CL-20) is a powerful new generation explosive. High values of density (ρ = 2.04 g/cm3) and enthalpy of formation (DНоf =377,410 ∙103 J∙mol-1) determine the unique energy characteristics of the product, and make it undoubtedly an attractive component for creating various formulations and products. Currently, intensive development is being carried out on the use of CL-20 in the formulations of energy-filled polymer compositions - mixed solid rocket fuels. It has been established that the use of CL-20 in mixed rocket propellants significantly increases the ballistic efficiency of the propellant. However, its widespread use in composite rocket fuel cells results in high cost. In the synthesis of CL-20, two-stage hydrogenolysis of 2,4,6,8,10,12-hexabenzylhexaazaisovurcitane takes place using an expensive palladium catalyst Pd/sibunite, which is subject to rapid deactivation. One of the main optimization tools is the variation of the properties of the carbon carrier. Nanodiamond is a high–strength carrier with a unique specific surface area.
DEVELOPMENT AND CREATION OF A STAND FOR INVESTIGATION OF ULTRASONIC IMPACT ON THE PROCESS OF DISSOLUTION OF CARBON DIOXIDE DURING ITS barbotage
Authors: Цыганок С.Н. , Абраменко Д.С. , Барсуков А.Р. , Шакура В.А.
Published: December 2023

Статья посвящена актуальной проблеме уменьшения углеродного следа от деятельности человека, а именно получение газогидрализатов при пропускании углекислого газа через водную среду. Проведен краткий анализ разных способов интенсификации такого процесса – абсорбции. Из рассмотренных методов как одним из перспективных предложено для интенсификации процесса абсорбции предложено применять механические колебаний ультразвуковой частоты высокой интенсивности. Для количественного анализа эффективности ультразвукового воздействия на процесс абсорбции углекислого газа разработана структурная схема измерительного стенда. Выработаны требования к создаваемому измерительному стенду, в соответствие с которыми подобраны первичные измерительные преобразователи и вспомогательное оборудование. Для оценки эффективности многофакторного эксперимента предложена параметрическая математическая модель поглощения углекислого газа в водной среде. В результате выполненной работы создан измерительный стенд для исследования ультразвукового воздействия на процесс растворения углекислого газа при его барботировании, на котором планируется в дальнейшем проводить экспериментальные исследования.

The article is devoted to the actual problem of reducing the carbon footprint from human activities, namely the production of gas hydrolysates by passing carbon dioxide through the aquatic environment. A brief analysis of different ways of intensifying such a process, absorption, has been carried out. Of the considered methods, as one of the promising ones, it was proposed to use high-intensity mechanical vibrations of ultrasonic frequency to intensify the absorption process. For quantitative analysis of the effectiveness of ultrasonic action on the process of carbon dioxide absorption, a block diagram of the measuring stand was developed. The requirements for the created measuring stand were developed, in accordance with which the primary measuring transducers and auxiliary equipment were selected. To evaluate the effectiveness of a multifactorial experiment, a parametric mathematical model of carbon dioxide absorption in an aquatic environment is proposed. As a result of the work performed, a measuring stand was created to study the ultrasonic effect on the process of dissolution of carbon dioxide during its barbotage, on which it is planned to carry out experimental studies in the future.
INFLUENCE OF FLUORIDE LEACHING ON THE PHASE COMPOSITION OF TITANOMAGNETITE ORE: DATA OF SCANNING ELECTRON MICROSCOPY
Authors: Орлов В.В. , Сачков В.И. , Князева Е.М. , Сачкова А.С.
Published: December 2023

Ванадийсодержащие титаномагнетитовые руды считаются одним из наиболее перспективных видов нетрадиционных руд и являются важным источником железа, титана и ванадия. Метод фторидной переработки с применением гидрофторида аммония является одним из наиболее перспективных, ввиду образования технологически приемлемых для дальнейшей переработки фторометаллатов аммония. В настоящей работе приводятся данные по морфологии и пространственному распределению элементов исходной титаномагнетитовой руды и твердого остатка после фторидной переработки. Для получения данных использовали метод сканирующей электронной микроскопии в режимах SE и BSE и проводили картирование по поверхности выбранной области. Минеральный состав представлен такими минералами, как ильменит, магнетит, титаномагнетит, магнезиоферрит, алюмосиликаты, кронстедтит и мейкснерит. Раствор NH4HF2 концентрацией 1 моль/л при 20°С позволяет извлечь Ti, Si, Alв форме фторометаллатов аммония и обогатить железом исходную руду. Таким образом, титаномагнетитовая руда Чинейского месторождения является перспективным сырьем и может быть переработана гидрометаллургическим способом по фторидной схеме.

Vanadium-containing titanomagnetite ores are considered one of the most promising types of unconventional ores and are an important source of iron, titanium and vanadium. The method of fluoride processing using ammonium hydrofluoride is one of the most promising, due to the formation of ammonium fluorometallates, which are technologically acceptable for further processing. This paper presents data on the morphology and spatial distribution of the elements of the original titanomagnetite ore and the solid residue after fluoride processing. To obtain data, the method of scanning electron microscopy was used in the SE and BSE modes and mapping was carried out over the surface of the selected area. The mineral composition is represented by such minerals as ilmenite, magnetite, titanomagnetite, magnesioferrite, aluminosilicates, cronstedtite and meixnerite. A solution of NH4HF2 with a concentration of 1 mol/l at 20°С makes it possible to extract Ti, Si, Al in the form of ammonium fluorometallates and to enrich the original ore with iron. Thus, the titanomagnetite ore of the Chiney deposit is a promising raw material and can be processed by the hydrometallurgical method according to the fluoride scheme.
DEVELOPMENT AND APPLICATION OF AN AUTOMATIC ADAPTATION SYSTEM BASED ON A SOFT SENSOR IN THE MODEL OF THE TECHNOLOGICAL PROCESS OF RECTIFICATION
Authors: Юрасов А.О. , Хафизов А.М. , Шулаева Е.А.
Published: December 2023

В данной работе описывается разработка система автоматической адаптации с применением виртуального анализатора в математической модели технологического процесса компьютерного тренажерного комплекса. Разработанная система автоматической адаптации способна в режиме реального времени предоставлять наиболее точную и достоверную информацию о будущем качестве получаемого продукта, тем самым способствуя повышению рабочих навыков персонала производственных предприятий, а также потенциальной прибыли производства при малых затратах, благодаря улучшению ведения технологического процесса и повышению показателей качества получаемого продукта. Выполненная работа состоит из нескольких частей, в которых приводится структурное описание системы автоматической адаптации, проблемы, возникающие на стадии разработки, основного описания выполнения расчетов, а также полученных результатов.

This paper describes the developed system of automatic adaptation using a virtual analyzer in a mathematical model of the technological process of a computer simulator complex. The developed system of automatic adaptation is able to provide the most accurate and reliable information about the future quality of the received product in real time, thereby contributing to the improvement of the working skills of the personnel of production enterprises, as well as the potential profit of production at low cost, thanks to the improvement of the technological process and the improvement of the quality indicators of the received product. The completed work consists of several parts, which provide a structural description of the automatic adaptation system, problems arising at the development stage, the main description of the calculations, as well as the results obtained.
DEVELOPMENT AND RESEARCH OF INTELLIGENT METHODS AND MODELS FOR PREDICTING PREDISPOSITION TO CARDIOVASCULAR DISEASES
Authors: Пужайкина А.Е. , Бубарева О.А.
Published: December 2023

Разработан метод оценки и прогнозирования в интеллектуальных системах поддержки принятия решений. Суть предлагаемого метода заключается в возможности анализа текущего состояния анализируемого объекта и возможности краткосрочного прогнозирования состояния объекта. Возможность объективного и полного анализа достигается за счет использования улучшенных нечетких временных моделей состояния объекта, улучшенной процедуры прогнозирования состояния объекта и улучшенной процедуры обучения эволюционирующих искусственных нейронных сетей. Процедура прогнозирования состояния объекта позволяет проводить многомерный анализ, учитывать и косвенно влиять на все компоненты многомерного временного ряда с различными временными сдвигами относительно друг друга в условиях неопределенности.

A method of evaluation and forecasting in intelligent decision support systems has been developed. The essence of the proposed method is the possibility of analyzing the current state of the analyzed object and the possibility of short-term forecasting of the state of the object. The possibility of objective and complete analysis is achieved through the use of improved fuzzy time models of the state of the object, an improved procedure for predicting the state of the object and an improved training procedure for evolving artificial neural networks. The procedure for predicting the state of an object allows for multidimensional analysis, taking into account and indirectly influencing all components of a multidimensional time series with different time shifts relative to each other under conditions of uncertainty.
Une utopie langagière : la glossolalie
Authors: DARRAULT-HARRIS Ivan
Published: December 2023

Notre article se présente comme un hommage conjoint à Michel de Certeau, l’auteur, à notre connaissance, de cette conception de la glossolalie comme utopie, et à Paolo Fabbri : leurs conversations à ce sujet ont été d’ailleurs publiées dans l’ouvrage Utopie vocali (Mimesis Edizioni, Milano-Udine, 2015). Le phénomène de la glossolalie, désignée à l’origine comme la « langue des anges », s’inscrit donc dans l’univers religieux, voire, plus précisément, néo-testamentaire et chrétien (la Pentecôte en est l’épisode culminant). Et l’on sait que le rite orthodoxe comprend toujours l’intervention glossolalisante d’un(e) fidèle, spontanément, le jour même de la Pentecôte, mimant la survenue de l’Esprit saint. Mais le phénomène glossolalique a glissé de l’univers religieux au profane, ainsi dans les manifestations en littérature, et du normal au pathologique. Et c’est bien au champ de la pathologie que nous voudrions nous attacher plus précisément, la glossolalie apparaissant chez certains sujets schizophrènes, relevant donc de la schizophasie. Des exemples montreront cette impressionnante manifestation d’une langue entièrement néologique, avec ses permanences (invariants phonologique et syntaxique) et ses règles de formation de véritables unités-phrases. Un exemple exceptionnel sera pris, celui d’un patient québécois disposant de cinq langages glossolaliques (ce cas nous a été communiqué par le célèbre aphasiologue André Roch Lecours). Le recours à la théorie des instances (J.-C. Coquet) permettra d’émettre une hypothèse sémiotique sur la survenue, chez le schizophrène, d’un tel phénomène, et cela à partir de ces ilôts limités dans le langage de ces patients que sont les mots néologiques et récurrents (appelés « predilection words ») au sein du langage normal préservé, y compris dans sa fonction métalinguistique. C’est le processus de reprise de l’expérience, le passage de la phusis au logos (selon les termes mêmes de Coquet) qui serait profondément atteint, engendrant la production inintelligible d’une pure expérience dans l’incapacité de se faire logos.
Le carré pathémique de l’identité discursive
Authors: Labiade Mohammed
Published: December 2023

En tant qu’outil d’analyse, certes non définitivement épuisé mais relativement opératoire, le carré sémiotique explicite la production du sens sur les plans de l’expression et du contenu. De Greimas à Coquet, le carré aristotélicien de la logique modale sous l’effet des concepts de modalité et d’identité bascule de la phorie au pathos. Le carré relatif à la phorie proposé pour étudier la compétence du sujet a été augmenté dans notre essai par un carré pathémique pour relever les rapports de sympathie ou d’antipathie entre les identités en interaction. Il caractérise la performance du sujet et non sa compétence. Dans le même esprit critique entamé par J. Petitot, c’est vrai moins pointilleux dans notre cas, nous souhaitons qu’un réexamen des priorités des différents modèles de carrés sémiotiques proposés jusqu’à nos jours puissent contribuer à l’interminable projet de la construction du sens.
El arraigo penal como instrumento de la tortura en México
Authors: Cobos Campos Amalia Patricia
Published: December 2023

La inconstitucionalidad del arraigo penal ha sido cuestionado en múltiples publicaciones y pareciera ocioso su abordaje, empero cobra aun mayor relevancia ante la reciente sentencia emitida por la Corte Interamericana de Derechos Humanos en el Caso Tzompaxtle Tecpile y otros vs México que vuelve a poner el dedo en la llaga de la existencia innegable de la tortura en este país; pese a las reformas constitucionales y la reestructuración de todo el Sistema Jurídico Mexicano, existen aún en dicho sistema figuras como la ya mencionada que consideramos favorecen la vulneración de los derechos humanos y muy en particular a la integridad corporal. El presente artículo es una investigación de corte teórico conceptual lo examina desde la perspectiva de los derechos humanos y parte de la hipótesis de que la sola existencia del arraigo pone en tela de juicio la tutela de las garantías judiciales más importantes tales como respeto a la integridad personal, presunción de inocencia y el debido proceso. Partimos de la utilización metodológica de la hermenéutica jurídica para un examen acucioso de las normas constitucionales, aplicándose igualmente la epistemología a efecto de examinar la doctrina pertinente al tema, utilizando como técnica básica la revisión de literatura especializada.
Protección constitucional de la víctima en Latinoamérica
Authors: Matos Quesada Julio César
Published: December 2023

La protección de la víctima de un delito carece de una dimensión constitucional general en las distintas constituciones de Latinoamérica, de tal forma que lo se protege en mayor medida, son los derechos fundamentales de los imputados, esto es, de los victimarios, por cuanto, increíblemente, existen los principios y garantías de protección hacia los derechos humanos de los delincuentes y criminales que se encuentran bajo el imperio de un proceso penal, el cual debe ser “justo” y “oportuno” para ellos. ¿Y la víctima? Es por ello que el objeto general, los retos políticos de las jurisdicciones constitucionales es el espacio ideal para intercambiar experiencias en cuanto a la manera cómo otros poderes judiciales de Latinoamérica han encarado los retos de la justicia transicional y la protección de los derechos de las víctimas. Razón por la cual, se comparten algunas reflexiones sobre la función que ha venido cumpliendo las distinta constituciones y sistema jurídico-penal en cada uno de los países de Latinoamérica. Una primera idea apunta a precisar conceptos, ya que con frecuencia oímos hablar de los derechos a la verdad, la justicia y la reparación de las víctimas sin tener mayor claridad acerca del origen y el significado de aquellos. Así las cosas, sea lo primero decir que la fuente primigenia de estos derechos es aquella del cumplimiento de buena fe de los tratados internacionales, que conduce a que los Estados partes se abstengan de vulnerar los derechos humanos (deberes negativos) y garanticen su ejercicio (deberes positivos).
A nanomedicine approach to targeting cuproplasia in cancer: Labile copper sequestration using polydopamine nanoparticles blocks tumor growth in vivo through altering metabolism and redox homeostasis.
Authors: Bonet Aletá Javier , Encinas-Giménez Miguel , Oi Miku , Pezacki Aidan T. , Sebastián Victor , de Martino Alba , Martín-Pardillos Ana , Martin-Duque Pilar , Hueso José L. , Chang Christopher J. , Santamaría Jesús
Published: December 2023

Copper plays critical roles as a metal active site cofactor and metalloallosteric signal for enzymes involved in cell proliferation and metabolism, making it an attractive target for cancer therapy. In this study, we investigated the efficacy of polydopamine nanoparticles (PDA NPs), classically applied for metal removal from water, as a therapeutic strategy for depleting intracellular labile copper pools in triple negative breast cancer models through the metal-chelating groups present on PDA surface. By using the activity-based sensing probe FCP-1, we could track the PDA-induced labile copper depletion while leaving total copper levels unchanged, and link it to the selective MDA-MB-231 cell death. Further mechanistic investigations revealed that PDA NPs increased reactive oxygen species (ROS) levels, potentially through the inactivation of superoxide dismutase 1 (SOD1), a copper-dependent antioxidant enzyme. Additionally, PDA NPs were found to interact with the mitochondrial membrane, resulting in an increase in mitochondrial membrane potential, which may contribute to enhanced ROS production. We employed an in vivo tumor model to validate the therapeutic efficacy of PDA NPs. Remarkably, in the absence of any additional treatment, the presence of PDA NPs alone led to a significant reduction in tumor volume by a factor of 1.66 after 22 days of tumor growth. Our findings highlight the potential of PDA NPs as a promising therapeutic approach for selectively targeting cancer by modulating copper levels and inducing oxidative stress, leading to tumor growth inhibition as shown in these triple negative breast cancer models.
Captopril molecules exhibit significant inhibitory effect for peroxidase-like nitrogendoped carbon dots
Authors: Hormozi Jangi Saeed Reza
Published: December 2023

In this continuation, the inhibitory effect of captopril molecules on the nanozymatic activity of peroxidase-like nitrogen-doped carbon dots was evaluated. In this regard, the carbon dots were synthesized via a simple hydrothermal method and then characterized for their FL properties and enzyme-like activity. Thereafter, the effect of captopril molecules on their nanozymatic activity was evaluated by calculating their nanozymatic activity in the presence and absence of captopril. The results reveal that the relative activity of nanozymes was inhibited by increasing the inhibitor concentration and finally reached 23% of its initial activity, revealing a strong inhibitory effect of captopril on the nanozymatic behavior of peroxidase-like nitrogen-doped carbon dots.
Beyond the Meso-/Macroporous boundary: Extending Capillary Condensation-based Pore Size Characterization in Thin Films Through Tailored Adsorptives
Authors: Füredi Máté , Vicente Manzano Cristina , Marton András , Fodor Bálint , Alvarez-Fernandez Alberto , Guldin Stefan
Published: December 2023

The characterization of thin films containing nanopores with diameters exceeding 50 nm poses significant challenges, especially when employing sorption-based techniques. Conventional volumetric physisorption or mercury intrusion methods have limited applicability to thin films, considering factors such as sample preparation time and the need for non-destructive testing. In this context, ellipsometric porosimetry (EP), represents a viable alternative. Its optical principle is highly sensitive to thin layers, offering insights into diverse structural parameters such as surface area, pore size, and porosity. While existing setups rely on capillary condensation of volatile compounds (such as water), their applicability is typically restricted to pore dimensions < 50nm. In this study, we introduce two high-molecular-weight hydrocarbon adsorptives, namely ethylbenzene and n-nonane to EP. These adsorptives show great promise in enhancing the accuracy of physisorption measurements beyond mesoporosity (>50 nm), extending the applicability up to 80 nm pores. The measurement guidelines established herein offer a non-destructive, expeditious (<60 min), low-pressure (<0.03 Bar) approach for investigating nanoporous thin films, with potential for adaptation to diverse structural architectures.
Neural tube defects: current view on etiology, prenatal prevention, and early diagnosis. A review
Authors: Chugunova Liliyana A. , Piskulina Alexandra A. , Kostiukov Kirill V.
Published: December 2023

A literature review on the etiology, prevention, and early diagnosis of neural tube defects is presented, focusing on the causes and risk factors for these disorders. Various pathogenetic mechanisms for neural tube defects and the role of folic acid in their prevention are described. The main stages of ultrasound evaluation of the central nervous system structures in the first trimester of pregnancy are addressed. A basic ultrasound imaging technique that allows to identify spina bifida is provided. This review aims to present current data on the etiology, prevention, and early diagnosis of neural tube defects. A search was conducted in domestic and foreign literature databases (eLIBRARY, Medline/PubMed, Embase, Crossref, RSCI) using the keywords "neural tube defect," "spina bifida," "prenatal diagnosis," "folic acid," "meningomyelocele," "myeloschisis." Twenty-five papers met the selection criteria and were included in the review. Healthcare providers' awareness of the methods of prenatal prophylaxis and the possibilities of early perinatal ultrasound diagnosis of neural tube defects will reduce their incidence and infant morbidity rates and increase the effectiveness of medical care.
MATLAB Simulation of Sinusoidal Pulse Width Modulation based Three and Seven Level Current-Source Inverters
Authors: M.S. Priyadarshini
Published: December 2023

Here, a multilevel current-source inverter (MCSI) topology is analyzed. Here, the issue of constructing a novelmodular single-rating inductor MCSI has been explored. The proposed topology isbuilt with identical modules where all inductors carry the sameamount of current, simplifying the construction and operationof industrial applications with higher efficiency. A new state machine approach with a proper implementation of the phase-shifted carrier-sinusoidal pulse width modulation (PSC-SPWM) allows both current balancein all modules and effective switching-frequency minimization. The performance of the MSCI proposed is simulated with MATLAB. As a result of this topology and PSC-SPWM utilization, current balance was achieved in both main and sharing inductors, even under load and operating point changes. The switching frequency was drastically reduced with a new state machine approach, taking the advantage of the three different zero-states of the topology. The topology adopted allows operation with high efficiency by reducing the current through the inductors and the losses in the switches.
МЕТОДОЛОГІЧНА СПЕЦИФІКА МІЖДИСЦИПЛІНАРНИХ ДОСЛІДЖЕНЬ НЕВЕРБАЛЬНИХ ЗАСОБІВ КОМУНІКАЦІЇ ХАРИЗМАТИКІВ
Authors: Бойченко М. К.
Published: December 2023

Статтю присвячено обґрунтуванню основних методологічних положень проведення міждисциплінарного вивчення взаємодії невербальних засобів у комунікації харизматичних мовців. Для реалізації мети дослідження виконано ретроспективний огляд наявних у лінгвістиці та у таких суміжних галузях наукового знання, як психологія, фізіологія, соціологія тощо, уявлень про взаємодію вербальних і невербальних елементів спілкування; розглянуто термінологічний апарат класифікацій невербальних засобів комунікації та визначено необхідність створення уніфікованої системи невербальних засобів у мовленні харизматиків. У праці розглянуто природу та методологічну сутність взаємодії вербальних і невербальних засобів, а наявну множину їх основних класів проаналізовано і зведено в систему у вигляді таблиці. З’ясувавши, що у вживанні харизматичним мовцем вербальних, невербальних і паравербальних засобів спілкування провідну роль відіграє правильний добір стратегії і тактик комунікації, авторка статті здійснила аналіз пропонованих у лінгвістичних дослідженнях стратегій і тактик харизматичного спілкування та мовленнєвого інструментарію їх реалізації, за результатами якого зафіксовано відсутність у працях більшості дослідників чіткої ієрархічної супідрядності та методологічних функцій зазначених понять. На основі системи цілей і засобів сугестивного впливу в комунікації, обґрунтованої вітчизняними науковцями Аллою Калитою і Ларисою Тараненко, у статті пропонується конвенціалізація низки стратегій, тактик, методів, способів і прийомів, уживаних харизматичними мовцями для здійснення сугестивного впливу на представників аудиторії, з метою усунення певних суперечностей у їх визначеннях. Вказано на перспективність конвенціалізації термінологічного апарату наукового опису результатів дослідження особливостей функціонування невербальних засобів у мовленні харизматиків та їх взаємодії з вербальними засобами за рахунок їх структурування у вигляді певної мегасистеми розглядуваних у статті понять.
The Role and Mechanism of Unfolded Protein Response Pathway in Tumor Drug Resistance
Authors: Han Yaqi , Zhou Bingjuan , Qiao Haizhi , Wang Lingyan , Zhang Jinku
Published: December 2023

In the process of tumor proliferation and metastasis, tumor cells encounter hypoxia, low glucose, acidosis, and other stressful environments. These conditions prompt tumor cells to generate endoplasmic reticulum stress (ERS). As a signal mechanism that mitigates ERS in eukaryotic cells, the unfolded protein response (UPR) pathway can activate cells and tissues, regulating pathological activities in various cells, and maintaining ER homeostasis. It forms the most crucial adaptive and defensive mechanism for cells. However, under the continuous influence of chemotherapy drugs, the quantity of unfolded proteins and erroneous proteins produced by tumor cells significantly increases, surpassing the normal regulatory range of UPR. Consequently, ERS fails to function properly, fostering tumor cell proliferation and the development of drug resistance. This review delves into the study of three UPR pathways (PERK, IRE1, and ATF6), elucidating the mechanisms of drug resistance and research progress in the signal transduction pathway of UPR related to cancers. It provides a profound understanding of the role and relationship between UPR and anti-tumor drugs, offering a new direction for effective clinical treatment.
Evaluation of Postoperative Psychological Distress and Its Driving Factors in Patients with Oral and Maxillofacial Malignant Tumors
Authors: Feng Yanqing , Lin Fengqiao , Huang Mengjun
Published: December 2023

Objective: To explore and analyze the evaluation and driving factors of postoperative psychological pain inpatients with oral and maxillofacial malignant tumors. Methods: Relevant data were collected from 80 patients with oral and maxillofacial malignant tumors who attended the outpatient clinic for follow-up consultations between May 2021 to May 2023. The patients used the psychological distress thermometer (DT) to circle words that best described their experiences in the past week, assigning a numerical value (0–10) to indicate their pain level on each day. The scoring results were employed to assess the psychological pain in these patients. A self-developed patient basic information questionnaire was utilized to record demographic details. Logistic regression analysis was employed to evaluate patients two weeks after surgery, focusing on the assessment of psychological distress and the identification and location of driving factors. Results: Following evaluation, the results revealed that the average postoperative DT score for the 80 patients with oral and maxillofacial malignant tumors was 4.53 ± 1.98 points. Scores < 4 points indicated no psychological pain (Group N) in 48 cases, while scores ≥ 4 points indicated psychological pain (Group Y) in 32 cases. The differences in postoperative DT scores among patients with varying educational levels, fears and worries about disease progression, economic problems, sleep problems, level of hope, and oral pain were statistically significant (P < 0.05). Multiple linear regression analysis results indicated that education level, fear and worry about disease progression, economic problems, sleep problems, level of hope, and oral pain are driving factors of postoperative psychological pain in patients with oral and maxillofacial malignant tumors (P < 0.05). Conclusion: The postoperative psychological pain level in patients with oral and maxillofacial malignant tumors is at a moderate level. Educational level, fear and worry about disease progression, economic problems, sleep problems, level of hope, and oral pain were identified as driving factors for postoperative psychological pain in these patients.
ABUSO DE PANTALLAS Y NORMALIZACIÓN DE LA VIOLENCIA EN LA PRIMERA INFANCIA: UNA REVISIÓN SISTEMÁTICA DE LA LITERATURA
Authors:   UNIVERSIDAD CATOLICA DE SANTA MARIA, AREQUIPA-PERU, CÁRDENAS LLAMOSAS LUCILA EVELINA
Published: December 2023

Los últimos años no han dejado de sorprender al mundo, y en un abrir y cerrar de ojos las pantallas han invadido todos los hogares, y han sido introducidos en la rutina familiar sin previo análisis de las posibles consecuencias, y más aún cuando se entregó ésta tecnología a los más pequeños, desde bebes que no llegan a cumplir un año, hasta niños que asisten a Centros de Educación Inicial, cuya característica innata en ellos es la curiosidad, ser activos, dinámicos pero que son silenciados cuando se enciende la luz azul que emiten celulares, tabletas entre otros y lo preocupante es que están expuestos a todo tipo de contenido, muchos de ellos altamente violento o terrorífico que no pasa ningún filtro de la supervisión paterna que pueda orientar sobre las acciones o valores que transmiten esos modelos de personajes, pero que aparecen en sus representaciones gráficas y hasta en sus juegos. Para la presente investigación se hizo una búsqueda de la literatura principalmente de artículos científicos, tomando en cuenta el intervalo entre los años 2018 y 2023, utilizando como bases de datos Scopus, Scielo, y principales revistas multidisciplinarias, también se incluyeron artículos de metaanálisis, revisiones sistemáticas entre otros. Los idiomas de dichos artículos fueron el inglés y español; se revisaron más de 50 artículos, pero solo se referenciaron 16 utilizando el gestor bibliográfico Mendeley. Palabras clave: abuso de pantallas, normalización violencia, primera infancia.
Packaging of an Amplifier Module for Sub-THz Wireless Transmission Based on Photonics
Authors: Kim Sooyeon , Choi Chan-Gyu , Moon Sang-Rok , Sung Minkyu , Kim Eon-sang , Song Ho-Jin , Jeong Hyunhak , Kim Seung Hwan , Cho Seung-Hyun
Published: December 2023

In this study, we have developed an amplifier waveguide module suitable for broadband communication in the sub-THz band. To achieve a waveguide module with excellent gain flatness characteristics, the effects of errors during the packaging procedures of the waveguide module and the space occupied by the bondwire were analyzed through an electromagnetic simulation. Furthermore, a photonics-based sub-THz wireless link with a carrier frequency of 288 GHz was established using a packaged amplifier module. The amplifier module was placed at the output of the sub-THz transmitter based on a uni-traveling-carrier photodiode and at the input of the sub-THz receiver. The maximum gain and 3 dB bandwidth of the amplifier module are 17.3 dB and 39 GHz, respectively. With this setup, we successfully transmitted a 100-Gbps 16-QAM modulated signal, employing a carrier frequency of 288 GHz, across a wireless distance of 100 m.
Design and Verification of a Miniaturized Multifunctional Transmitarray Unit Cell for the S-Band
Authors: Kim Gyoungdeuk , Hwang Myeongha , Lee Ingon , Kim Sangkil
Published: December 2023

In this paper, a miniaturized multifunctional unit cell structure of a transmitarray operating at S-band and its verification method using a waveguide structure is presented. The unit cell of a multifunctional transmitarray antenna is a critical component because it controls the phase and polarization of an incident wave. The proposed unit cell consists of three main parts: an Rx antenna, a Tx antenna, and a control circuit for phase and polarization. The performance of the designed unit cell is verified by a rectangular waveguide structure. The waveguide structure feeds an electromagnetic wave propagating in a TE10 mode to a 1 × 2 unit cell array to verify polarization and phase shifting capability of the unit cell. The phase shifting and polarization conversion capabilities of the proposed unit cell are directly measured by the radiation patterns and polarization of the transmitted wave.