bluuebunny/crossref_metadata_2025 huggingface dataset:
Production of sphere-like bacterial cellulose in cultivation media with different carbon sources: a promising sustained release system of rifampicin
Authors: Lazarini Silmara Cristina , Yamada Caroline , Nóbrega Tainá Rosa da , Lustri Wilton Rogério
Published: March 2022

Bacterial cellulose (BC) production can be performed using a static or agitated culture method. In the static culture method, the BC is obtained presents three-dimensional thinner network structures and excellent mechanical properties. In the agitated culture method, BC is produced in the form of granules or fibrous threads with a lower degree of polymerization, mechanical strength, and crystallinity than those formed in static fermentation. Compared with BC membranes, sphere-like BC (SBC) cultured under agitated conditions showed advantages for adsorption due to its larger surface area. The objectives of this work were to obtain SBC, by the bacterial strain Komagataeibacter hansenii ATCC 23769, in agitated cultivation, using media containing different carbon sources carbon sources, such as fructose (FRU), glucose and sucrose (MS1), sucrose (Y) and glucose (Z and HS), aiming to produce supports for sustained release of rifampicin (RIF). SBC has been produced under agitation at 130 rpm and 25°C. SBC obtained were processed to remove bacteria and residues from the culture media and lyophilized. The SBC characterizations were performed by Fourier transform infrared spectroscopy, X-ray diffraction, Field emission gun-scanning electron microscopy, thermogravimetric, and by derivative thermogravimetry analysis. The SBC produced were impregnated with antibiotic RIF and tested for the sustained release capacity of this drug by diffusion method and Frans cell kinetics. SBC that the best results for all tests were produced in FRU, Z and MS1 media, respectively. The results demonstrate the potential of the SBC to contribute to the design of new drug delivery systems with biomedical applications.
The Effect of Proton Pump Inhibitor use on Survival of Patients With Colorectal Cancer. A Study of a Racially Diverse Population
Authors: Obeidat Adham Eyad , Monti Gabriel , Choi Horyun , Acoba Jared
Published: March 2022

PurposeProton pump inhibitor (PPI) use is increasing in the general population. Chronic PPI use can lead to hypergastrinemia, which has been purported to increase the risk of developing colorectal cancer (CRC). Several studies have failed to report any association between PPI use and the risk of CRC. However, little is known about the effect of PPI use on CRC survival. In this retrospective analysis, we studied the effect of PPI use on CRC survival in a racially diverse population.MethodsData were abstracted for 1050 consecutive patients diagnosed with CRC from January 2007 to December 2020. Kaplan-Meier curve was created to study the effect of PPI exposure compared to no exposure on overall survival (OS). Univariate and multivariate analyses were performed to investigate predictors of survival.ResultsComplete data were available for 750 patients with CRC, 52.5% were males, 22.7% Whites, 60.1% Asians, and 17.2% Pacific-Islanders. 25.6% of patients had a history of PPI use. Moreover, 79.2% had hypertension, 68.8% had hyperlipidemia, 38.0% had diabetes mellitus and 30.2% had kidney disease.There was no difference in median OS among PPI users compared to non-users, p value= 0.4. Age, grade, and stage were predictors of inferior OS. No significant association was noticed with gender, race, comorbidities, or treatment with chemotherapy.ConclusionIn this retrospective analysis of a racially diverse population of CRC patients, we found that PPI use was not associated with worse OS. Until high quality prospective data are available, physicians should not stop PPIs that are clinically indicated.This article is present on a preprint server of Research square website and can be accessed on https://www.researchsquare.com/article/rs-796911/v1. This article is not published nor is under publication elsewhere.
Urban-rural disparities in the healthy aging trajectory in China: a population-based study
Authors: Li Haomiao , Zeng Yixin , Gan Li , Tuersun Yusupujiang , Yang Jiao , Liu Jing , Chen Jiangyun
Published: March 2022

Purpose: The aim of this study is to explore the differences and evaluate the equity in healthy aging trajectories between urban and rural areas in China. The hypothesis of this study is that there are differences in healthy aging trends between urban and rural areas, with inequity. Methods: A total of 9402 respondents aged 45 years and older interviewed in four waves were selected from the China Health and Retirement Longitudinal Study. A latent growth mixture model (LGMM) was applied to distinguish the trajectory of healthy aging. A multinomial logistics regression model (MLRM) was used to explore the relationship between urban-rural areas and healthy aging trajectories, and a concentration index was used to evaluate equity. Results: Urban-rural respondents differed in socioeconomic background, family characteristics, and personal lifestyle ( P < 0.05). Three classes (“low risk”, “middle risk”, and “high risk”) were grouped through LGMM. The MLRM results showed that urban living was significantly associated with a healthy aging trajectory (for [middle risk/low risk]: β=-0.41, RRR =0.66, P < 0.001, 95% CI =0.55–0.80, and for [high risk/low risk]: β=-1.10, RRR =0.33, P < 0.001, 95% CI =0.26–0.41). The concentration index was -0.022 and significantly indicated the inequity of healthy aging between rural and urban areas. Conclusion: Combined health status showed an irreversible downward trend with age, and this trajectory differed between urban and rural areas, with the rural population more likely to develop a high risk trajectory. Policy inclination and resource investment should be enhanced to reduce inequity in healthy aging between urban and rural areas in China.
Condicionantes para o licenciamento ambiental de três rodovias na Amazônia Legal: BR-429/RO, BR-242/TO e BR-163/MT
Authors: Leite Fernanda Helena Ferreira , Almeida Alexandre Nascimento de , Angelo Humberto
Published: March 2022

A emissão das licenças ambientais implica na determinação de condicionantes para que os empreendimentos causem o mínimo de impactos ambientais negativos possíveis. O objetivo do estudo é avaliar o cumprimento das condicionantes de licenças de instalação de três rodovias na Amazônia Legal. O método é a pesquisa documental, utilizando como material os processos das licenças dos trechos das rodovias BR-429, em Rondônia, BR-242, em Tocantins, e BR-163, em Mato Grosso. Os resultados indicaram uma extensa lista de condicionantes administrativas, o não cumprimento de várias condicionantes técnicas e a constatação de que alguns programas ambientais não foram realizados, ainda que previstos no licenciamento ambiental. Os resultados apontaram para a necessidade de aprimoramento dos estudos ambientais, com o acompanhamento e fiscalização mais efetivos pelos órgãos responsáveis, assim estimulando o seu fortalecimento institucional.
Exceptional points and pseudo-Hermiticity in real potential scattering
Authors: Loran Farhang , Mostafazadeh Ali
Published: March 2022

We employ a recently-developed transfer-matrix formulation of
scattering theory in two dimensions to study a class of scattering
setups modeled by real potentials. The transfer matrix for these
potentials is related to the time-evolution operator for an associated
pseudo-Hermitian Hamiltonian operator \widehat{\mathbf{H}}𝐇̂
which develops an exceptional point for a discrete set of incident
wavenumbers. We use the spectral properties of this operator to
determine the transfer matrix of these potentials and solve their
scattering problem. We apply our general results to explore the
scattering of waves by a waveguide of finite length in two dimensions,
where the source of the incident wave and the detectors measuring the
scattered wave are positioned at spatial infinities while the interior
of the waveguide, which is filled with an inactive material, forms a
finite rectangular region of the space. The study of this model allows
us to elucidate the physical meaning and implications of the presence of
the real and complex eigenvalues of \widehat{\mathbf{H}}𝐇̂
and its exceptional points. Our results reveal the relevance of the
concepts of pseudo-Hermitian operator and exceptional point in the
standard quantum mechanics of closed systems where the potentials are
required to be real.
Een archivalische tour de force
Authors: Van der Meulen Jim
Published: March 2022

Review of Johan Van Der Eycken, Ridders aan de Maas. Adel in het graafschap Loon (1300-1520), Studies in Belgian History 8 (Brussel: Algemeen Rijksarchief, 2020, 367 p., ill.)
Buitenplaatsen in het brandpunt van de geschiedenis. Vernieuwende monografieën tussen micro-histoire en het grote historische narratief
Authors: Ronnes Hanneke
Published: March 2022

Review of Conrad Gietman en Jorien Jas, red., Biljoen: Kasteel, bewoners, landschap (WBooks: Zwolle, 2020, 360 p., ill.), and Yme Kuiper en Sjoerd Cuperus, Dekema State Jelsum: Biografie van een landgoed (Noordboek: Gorredijk, 2020, 704 p., ill.).
The Grand Tour. A trial of aristocratic manhood
Authors: Clark Samuel
Published: March 2022

Review of Sarah Goldsmith, Masculinity and danger on the eighteenth-century Grand Tour (London: University of London Press, Institute of Historical Research, 2020, xiii + 272 p., index).
Electrochemical Synthesis of Germanium-Polypyrrole Composite Nanomaterials in Ionic Liquids for the Fabrication of Lithium-Ion Batteries
Authors:   Institute of Electrochemistry, Clausthal University of Technology, Arnold-Sommerfeld-Strasse 6, 38678 Clausthal-Zellerfeld, Germany, Liu Zhen , Yang Li ,   Institute of Electrochemistry, Clausthal University of Technology, Arnold-Sommerfeld-Strasse 6, 38678 Clausthal-Zellerfeld, Germany, Lahiri Abhishek ,   Department of Chemical Engineering, Brunel University London, Kingston Lane, Uxbridge UB8 3PH, Middlesex, England, Rohan James F ,   Electrochemical Materials and Energy Group Tyndall National Institute, University College Cork, Lee Maltings, T12 R5CP Cork, Ireland, Endres Frank ,   Institute of Electrochemistry, Clausthal University of Technology, Arnold-Sommerfeld-Strasse 6, 38678 Clausthal-Zellerfeld, Germany
Published: March 2022

Herein, we report the coating of nanostructured germanium using a polypyrrole (PPy) polymer coat as a composite anode material for the fabrication of lithium-ion batteries. The Ge/PPy composites were synthesized following the direct electrochemical deposition method in an ionic liquid (IL). The results revealed that the coating of PPy on Ge helped realize stable battery cycling and reversible capacities, which were not observed in uncoated Ge. The PPy layers could effectively inhibit side reactions between the electrode and electrolyte. The composition of the solid electrolyte interphase (SEI) formed after lithiation/delithiation cycles were analyzed using the X-ray photoelectron spectroscopy (XPS). Compact SEI layers consisted of decomposed TFSI− anion products such as LiF, Li2S, Li2NS2O4, and Li2CO3 at the Ge-PPy/IL interphase. In contrast, thick SEI layers consisted of not only decomposed TFSI− anion and [Py1,4]+ cation products but also chemically or physically adsorbed IL compounds at the Ge/IL interphase. In addition, the PPy coating could effectively inhibit Ge oxidation, resulting in improved battery capacity.
Effectiveness of Mobile Apps in Promoting Healthy Behavior Changes and Preventing Obesity in Children: Systematic Review
Authors: Yau Kiana W , Tang Tricia S , Görges Matthias , Pinkney Susan , Kim Annie D , Kalia Angela , Amed Shazhan
Published: March 2022

Background

Mobile apps have been increasingly incorporated into healthy behavior promotion interventions targeting childhood obesity. However, their effectiveness remains unclear.

Objective

This paper aims to conduct a systematic review examining the effectiveness of mobile apps aimed at preventing childhood obesity by promoting health behavior changes in diet, physical activity, or sedentary behavior in children aged 8 to 12 years.

Methods

MEDLINE, Embase, PsycINFO, CINAHL, and ERIC were systematically searched for peer-reviewed primary studies from January 2008 to July 2021, which included children aged 8 to 12 years; involved mobile app use; and targeted at least one obesity-related factor, including diet, physical activity, or sedentary behavior. Data extraction and risk of bias assessments were conducted by 2 authors.

Results

Of the 13 studies identified, most used a quasi-experimental design (n=8, 62%). Significant improvements in physical activity (4/8, 50% studies), dietary outcomes (5/6, 83% studies), and BMI (2/6, 33% studies) were reported. All 6 multicomponent interventions and 57% (4/7) of standalone interventions reported significant outcomes in ≥1 behavioral change outcome measured (anthropometric, physical activity, dietary, and screen time outcomes). Gamification, behavioral monitoring, and goal setting were common features of the mobile apps used in these studies.

Conclusions

Apps for health behavior promotion interventions have the potential to increase the adoption of healthy behaviors among children; however, their effectiveness in improving anthropometric measures remains unclear. Further investigation of studies that use more rigorous study designs, as well as mobile apps as a standalone intervention, is needed.
Dissemination and implementation research in health recommender systems: a systematic scoping review and evidence map (Preprint)
Authors: Sun Yue , Ji Mengmeng , Zhou Jia , Wang Zhiwen
Published: March 2022

BACKGROUND

Health recommender systems (HRSs) are information retrieval systems that provide users with relevant items according to the users’ needs, which can motivate and engage users to change their behavior.

OBJECTIVE

The aim of this scoping review was to give an overview of the state of the evidence on implementation and the gaps of HRSs and create an evidence map.

METHODS

We conducted a systematic literature review according to the PRISMA Extension for Scoping Reviews (PRISMA-ScR) guidelines and synthesized the results. Six databases were searched to identify HRSs reported in studies from inception to June 1, 2021 followed by forward citation and gray literature searches. Titles, abstracts, and full texts were screened independently by two reviewers, with discrepancies resolved by a third when necessary. Data extraction was performed by one reviewer and checked by a second reviewer.

RESULTS

A total of 46 studies were included for data extraction. Recommended items were classified into four major categories: general health promotion, lifestyle, generic health service and other domains. A total of 22 studies have reported the use of hybrid recommendation systems, which are the most commonly used recommender techniques in HRSs. A total of 28 studies reported the user interface of HRSs, and most HRSs work on users’ mobile interfaces, usually through a mobile app. Two categories of HRS evaluations were used, and evaluations of HRSs vary greatly. Half of the studies only evaluated the algorithm with various metrics, whereas only a few studies reported assessments involving users to evaluate HRSs.

CONCLUSIONS

Through this scoping review, nonmedical professionals and policymakers can visualize and better understand HRSs in future studies. HRS has been increasingly used in recent years, but there are many unique challenges associated with HRS. There is a lack of scientific evidence in user-centered evaluation approaches, and some other metric parameters vary in HRSs. Further studies should be proposed pertaining to HRS in other therapeutic areas apart from lifestyle and generic health services.
Masterplan Pengembangan Desa Wisata Gerbosari Kecamatan Samigaluh Kabupaten Kulon Progo
Authors: Wihastuti Latri , Oktavia Rina
Published: March 2022

Tourism development has become an option in many areas as a way to reduce poverty. One of the resources developed as a source of income is natural and cultural resources which are exploited as tourist objects and attractions. Tourism can be developed to improve the economy that is directly towards the community around attractions. Gerbosari Village is one of the leading villages in Samigaluh Subdistrict, Kulonprogo Regency which has a special tourism potential for use by tourist villages. The potential given by Gerbosari Village is a chrysanthemum plant whose data grows well, ponders beautiful nature, and harmonious community culture. The Village Government and Gerbosari Residents have a strong commitment to managing the potential of the village and creating innovations to enhance development through local tourism development. To realize the developed tourist village and provide direction to the welfare needed by the Gerbosari Tourism Village development masterplan. Based on the results of the preparation of the Gerbosari Tourism Village Development Masterplan, several Tourism Village objects that will be developed in the next 5 years include chrysanthemum agro-tourism areas, educational tours for the use of home yards, Camping ground and tracking of Jongkang Mountain, and the peak Cultural Tourism of Suroloyo.
STRATEGI PENGEMBANGAN TAMAN EDUKASI PERTANIAN DI DESA GERBOSARI KECAMATAN SAMIGALUH KABUPATEN KULON PROGO
Authors: Andari Yuni , Yuniyarti Nur Aini
Published: March 2022

Desa Gerbosari secara administrasi terletak di wilayah Kecamatan Samigaluh Kabupaten Kulon Progo Provinsi DIY. Desa Gerbosari memiliki potensi alam dan pertanian yang dapat dikembangkan menjadi potensi wisata berbasis alam dan agro, namun permasalahan yang dihadapi desa ini adalah ketersediaan sarana dan prasarana fisik maupun non fisik yang belum memadai yang dapat menunjang program desa wisata tersebut. Salah satu kegiatan yang dapat menunjuang program pengembangan desa wisata di Desa Gerbosari yaitu pembuatan taman edukasi pertanian, namun kurangnya pengetahuan dan keterampilan pengelola wisata dan pemerintah desa dalam pembuatan taman edukasi menjadi salah satu masalah yang dihadapi. Pengabdian Kepada Masyarakat ini bertujuan memberikan pelatihan dan pendampingan pembuatan taman edukasi pertanian dalam rangka meningkatkan pengetahuan dan keterampilan pengelola wisata dan anggota masyarakat dalam pembuatan taman edukasi pertanian. Khalayak sasaran dari kegiatan ini adalah anggota kelompok PKK Desa Gerbosari. Pelatihan diberikan oleh tenaga ahli yang disediakan oleh tim pengabdian SV UGM. Kegiatan pelatihan melibatkan kelompok masyarakat dan institusi Desa Gerbosari, serta Sekolah Vokasi UGM. Kegiatan pelatihan tersebut telah menambah pengetahuan dan keterampilan anggota kelompok PKK sebagai salah satu pengelola desa wisata dalam hal pembuatan taman edukasi pertanian.
Pelatihan Basic Safety Training (BST) & SKK 30 /60 Mil kepada Kru Kapal untuk Meningkatkan Keselamatan Pelayaran Kapal Penyeberangan Penumpang di Kawasan Wisata Labuan Bajo
Authors: Andromeda Vega Fonsula
Published: March 2022

Polikteknik Ilmu Pelayaran Semarang bekerjasama dengan KUPP Labuan baju menyelenggarakan DPM KLM dan SKK 30/60 Mil Labuan Bajo. Tim Diklat Keterampilan Khusus Pelaut memberikan pelatihan Basic Safety Training (BST) kepada crew kapal penyebrangan di Labuan Bajo pada kegiatan pengabdian imasyarakat. PIP iSemarang menugaskan narasumber ahlii dari dosen/praktisi dalam rangka menolong memberikan penyuluhan tentang pentingnyai keselamatan dasar dalam rangka survival di laut. Crew kapal penyebrangan lokal bergegas melakukan prinsip dasar keselamatanl dan bertahan di laut pada saat melakukan pekerjaanya rutinitasnya sehingga sesuaii pada aturan-aturan pelayarani dan menciptakan suasana aman dan nyamani pada saat berlayar.
ОБЗОР НОВИНОК КОМПАНИИ MAXIM INTEGRATED
Authors: Садеков Д.
Published: March 2022

В номенклатуру продукции компании Maxim Integrated входит более 6000 наименований изделий, среди которых аналоговые и цифровые компоненты, микросхемы смешанного сигнала. В статье представлен краткий обзор новинок Maxim Integrated, анонсированных в прошлом году.
Investigation of Different Deep Neural Networks for the Diagnostics of Brain Tumor, Skin Cancer and Breast Cancer
Authors: Nimje Riya , Paliwal Shreya , Saraf Jahanvi , Chavan Prof. Sachin
Published: March 2022

Abstract: Early disease detection cannot be neglected in the healthcare domain and especially in the diseases where risk is associated with a life of a person. As per the WHO, if diseases can be predicted ahead of time, death rates can be reduced. The paper's goal is to investigate how to detect Breast Cancer, Skin Cancer, and Brain Tumor at the early stages with the help of Deep Learning techniques. The authors of different papers have used different techniques and Algorithms like Convolutional Neural Network (CNN) algorithms, Visual Geometry Group (VGG16) and Residual Network (ResNet). We tried to investigate these three algorithms and compared them to find out the most efficient amongst them for each disease. Keywords: Breast Cancer, Skin Cancer, Brain Tumor, Deep Learning, CNN, VGG and ResNet
A RITUALIZAÇÃO DO RURAL CONTEMPORÂNEO: NOTAS SOBRE CHOUPANA DO GAVIÃO
Authors: Coghetto Franciele , Villwock Ana Paula Schervinski , Hillig Clayton
Published: March 2022

A multifuncionalidade do rural aborda a ampliação das funções sociais, ambientais, patrimoniais e alimentares através das funções simbólicas atribuídas ao rural, deixando-o de ser entendido apenas como produtor de bens agrícolas. Diante disso, este estudo tem como objetivo analisar os novos sentidos construídos através da ritualização do rural contemporâneo, tendo como área de estudo circunscrita à região do Alto Uruguai gaúcho e campo empírico a Choupana do Gavião. Trata-se de uma pesquisa de cunho antropológico, fundamentada na etnografia, que teve como ferramentas a observação participante, entrevistas em profundidade e questionários. Desta forma, se compreende que o meio rural, na pós-modernidade se transforma, deixa de ser um espaço meramente agrícola e passa a ser um espaço de multifuncionalidades, que se orientam em grande medida pela ritualização do espaço rural, apresentando múltiplos interesses onde circulam as novas construções do rural contemporâneo, exercendo funções sociais, ambientais e patrimoniais que podem ser acessadas através de bens simbólicos, como a religiosidade e espiritualidade. Ou seja, rural é mais que um espaço de produção de alimento para o corpo físico, ele é um espaço que nutre as relações dos seres humanos, espiritualidade e a natureza.
Existential Foundations of the "Mystical Experience"
Authors: Naidysh Viacheslav Mikhailovich , Naidysh Olga Viacheslavovna
Published: March 2022

In the existing philosophical interpretations of mystical experience (constructivism, essentialism, etc.), its essence is usually seen in the features of "mystical knowledge". At the same time, the value-semantic foundations of mystical experience and its existential aspect remain in the shadows. In this article, the mystical experience is analyzed from the standpoint of the theories of the subject's objective activity - the theory of activity (developed in Russian psychology), enactivism, and the concept of the "life world". It is shown that the essence of mystical experience is manifested not in cognitive, but in value-semantic, existential attitude to the world, which is represented by two groups of value-semantic viewpoints. In the first, the dependence of the subject on the sacred object of mystical experience is expressed, in the second - the volitional focus of the subject on overcoming such dependence, "mastering", "acquiring" the sacred object. These attitudes reflect the duality of the need-motivational sphere of consciousness, which gives the activity of the subject, on the one hand, activity, energy, and on the other, meaning. In mystical experience, the subject of active "development", "acquisition" (which can be both real and virtual) is an imaginative "otherworldly reality". The analysis allows us to conclude that mystical experience is one of the forms of motivational states of consciousness. Its peculiarity is that it is aimed at realizing the need for the harmonization of the subject's relations with the natural and social environment, the subject's finding the meaning of the "existence of his self" in an always open to the future, incomplete life world. It is the motivational basis that gives the mystical experience an improvisational character, as well as a creative, renewing potential (within the boundaries of the sensory-emotional experience of the world by the subject). The article also analyzes the concept of semantic reality. It is shown that the semantic foundations of mystical experience reflect the individually unique aspects of human life, are the result of the interactions of many factors of socio-cultural, individual-personal nature (psychological, medical, pharmacological, gender, psychiatric, etc.).
Contemporary Russian Philosophy: An Experience of Anthology
Authors: Malinov Alexey Valerievich , Rybas Aleksandr Evgenievich
Published: March 2022

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The Implementation of Arabic Vocabulary Learning Strategies Design Based on Howard Gardner's Multiple Intelligences /Penerapan Desain Strategi Pembelajaran Kosa-Kata Bahasa Arab Berbasis Multiple Intelligences Howard Gardner
Authors: Nadhif Nadhif
Published: March 2022

The students’ failure to catch learning information can be caused by some factors, such  as the unsuitability between teacher’s teaching strategies and students’ learning strategies. This paper is motivated by some teachers who have difficulties in implementing multiple intelligences and their need for closeness to the design of multiple intelligence-based mufrodat learning strategies that facilitate students 'comprehension and strengthen students' memories as the main provision for mastering four Arabic language skills. Through qualitative literature research taken from books and previous research that had been analyzed using descriptive analysis, it is founded that the teachers’ difficulties in designing Multiple Intelligences-based learning strategies can be caused by two factors; the focus on determining activities based on one type of intelligence and one-way learning paradigm. The design of a multiple intelligence-based learning strategy contains three components; first, the design of learning activities that contains various types of intelligence, two, paradigms of two-way learning, and third, the existence of activities to facilitate students’ comprehension and strengthen students' mufrodat memory through the use of the highest learning modalities, linking material with life safety, packaging material with emotions and giving appreciation of student learning progress.
Different factors dominate in each guild in Aculeata communities along an elevational gradient in a boreal forest
Authors: Uemori Kazushige , Mita Toshiharu , Hishi Takuo
Published: March 2022

The response of communities to climate change is expected to vary among
feeding guilds. To evaluate the response of guilds to environmental
factors without considering the taxonomic specificities, it is useful to
examine Aculeata bees and wasps, which consist of closely related taxa
including different guilds, pollinators, predators, and parasitoids. In
this study, we evaluated changes in species diversity (SD) and
functional traits of each feeding guild along an elevational gradient in
a boreal forest in northern Japan. We used yellow pan traps to collect
Aculeata bees and wasps at 200–1600 m above sea level. We investigated
six functional traits (trophic level, flight duration, body size,
elevational range, nesting position, and soil dependency) and the
horizontal distribution of the species. The SD of all Aculeata predators
and parasitoids decreased with an increase in elevation; however, the SD
of pollinators did not show any specific trend. Although the functional
trait composition of all Aculeata species did not show any trend, that
of each feeding guild responded to elevation in different ways.
Pollinators increased in body size and showed a decrease in flight
duration with increasing elevation, suggesting that tolerance and
seasonal escape from physical stress at high elevations are important
for shaping pollinator communities. Predators showed increased
elevational range and above-ground nesting species with increasing
elevation, suggesting that the ability to live in a wider range of
environments and avoid unsuitable soil environments at high elevations
might be important. Parasitoids changed their hosts and variable traits
with increasing elevation, suggesting that brood parasitoids have
difficulty in surviving at high elevation. The traits for each guild
responded in different ways, even if they were dominated by the same
environmental factors. Differences in the response of functional traits
would produce different patterns of community formation in different
guilds during further climate change.
Phylogenetic relationship and biogeography of the genus Diestramima, a cave cricket endemic to the Oriental realm (Rhaphidophoridae: Aemodogryllinae)
Authors: Zong Jingsong , Qin Yanyan , Shen Chuze , HE Zhu-Qing , Li Kai
Published: March 2022

Diestramima is only distributed in the Oriental realm, and mainly in
China. Because they are apterous, these insects are good materials for
studying biogeography. In this study, we reconstruct the phylogeny tree
of Diestramima species based on maximum likelihood and Bayesian
inference based on six genes, and use fossil-based molecular dating and
ancestral range estimation to reconstruct the dispersal route. The
results of molecular system are highly consistent with the morphological
characteristics of these species. The distribution area of a species has
an important influence on their interspecific differentiation. Dating
and historical biogeography analyses suggest an early Miocene origin of
the genus. Some ancestors of the genus Diestramima have been distributed
in Guangxi, Yunnan province and other regions of China at this time. In
the late Miocene, the genus Diestramima dispersed from the low mountain
and hilly areas of Guizhou, Guizhou and Hunan to inland China. With the
uplift of the Qinghai-Tibet Plateau and the drop in temperature in the
Neogene leading to the divergence within this genus. Diestramima
gradually spread from Guangxi and Yunnan to Chinese inland area.
Quaternary glaciation determines their current geographical distribution
pattern. Southeast Asia is the most likely original place of the genus
Diestramima.
Fabrication of amino acid conjugated Polymeric Micelles for controlled anticancer drug delivery using Radiation and pH-stimuli-triggering systems
Authors: Tsai Hsieh-Chih , Addisu Kefyalew Dagnew , Lee Wen-Yi , Wu Szu-Yuan
Published: March 2022

Drug delivery to the tumor site and minimizing adverse effects on
surrounding tissues remains a fundamental issue. In this study, pH and
radiation-responsive PLGA-PEG-PLGA amphiphilic copolymers were
terminally conjugated with hydrophobic tryptophan (Try), tyrosine (Tyr),
or histidine (His) amino acids (aa). To synthesize the tri-copolymers,
PEG was employed as an initiator and Sn (Oct) as a
catalyst. In this system, micelles were developed with an inner core
comprised of hydrophobic blocks (PLGA and Try/Tyr/His) and PEG as a
hydrophilic corona to improve the stability. The rise in DOX
fluorescence intensity and particle size shift because of light and pH
stimulation supported structural destabilization of the micelle.
Try-PLGA-PEG-PLGA-Try and Tyr-PLGA-PEG-PLGA-Tyr micelles had negligible
cytotoxicity (more than 90% cell viability at 100 g/mL) when incubated
with NIH-3T3 and HeLa cell lines using MTT assays. DOX-loaded micelles
(Try/Tyr), on the other hand, had a greater impact on HeLa cells, with
roughly 30% of cells were survived at a maximum DOX dosage (10 g/mL).
The cellular uptake experiment further verified that DOX-loaded micelles
were internalized in the cytoplasm and nucleus of cancer cells.
Therefore, the prepared copolymer systems have the potential to be
employed as stimuli-responsive carriers for the delivery of anti-cancer
drugs.
Pregnancies in women with previous complete uterine ruptures
Authors: Al-Zirqi Iqbal , Vangen Siri
Published: March 2022

Objective: To study the outcomes of new pregnancies after previous
complete uterine rupture. Design: Descriptive study based on population
data from the Medical Birth Registry of Norway, the Patient
Administration System, and medical records. Sample: Maternities with
previous complete uterine rupture in Norway during the period 1967–2011
(N=72), extracted from 2 455 797 maternities. Method: We measured the
rate of new complete ruptures and partial ruptures, as well as the
maternal and perinatal outcomes of these pregnancies. The
characteristics of both previous ruptures and new ruptures were
described. Results: Among 72 maternities, there were thirty-seven with
previous ruptures in the lower segment (LS) and 35 outside the LS. We
found three new complete ruptures and six uneventful partial ruptures,
resulting in a rate of 4.2% and 8.3%, respectively. All three complete
ruptures occurred preterm in scars outside the LS. The rate of new
complete rupture was 0% in those with previous rupture in the LS, and
8.6% in previous ruptures outside the LS. The corrected perinatal
mortality was 1.3%, and prematurity (<37 weeks) was high
(36.1%); this was noticed even in the absence of new ruptures and was
mostly iatrogenic. Two hysterectomies were performed in the absence of
rupture and two cases had abnormal invasive placenta. Conclusion: The
prognosis for pregnancies after previous complete uterine rupture is
favorable. Prematurity is a problem caused by both obstetrician and
mother anxiety, so the timing of delivery is most challenging. Careful
counseling, vigilance for symptoms, and immediate delivery are most
important.
Predicting preterm birth through vaginal microbiota, cervical length and WBC using a machine learning model
Authors: Park Sunwha , Moon Jeongsup , Kang Nayeon , Kim Younghan , You Young-Ah , Kwon Eunjin , Ansari AbuZar , Hur Young Min , Park Taesung , Kim Young Ju
Published: March 2022

Objective: To select markers that improve predictive power through
machine learning among various vaginal microbiota and develop an
excellent prediction algorithm that combines clinical information.
Design, setting and population: A multicenter case-control study with
150 Korean pregnant women. Methods: Cervicovaginal fluid were collected
from pregnant women during mid-pregnancy. Their demographic profiles,
white blood cell count, and cervical length were recorded, and the
microbiome profiles of the cervicovaginal fluid were analyzed. The
subjects were randomly divided into a training and a test set. A
univariate analysis was performed to select markers using seven
statistical tests. Using the selected markers, machine learning models
were used to build prediction models. Main outcome measures: The preterm
birth prediction model showed sensitivity of 79% and specificity of
83% (AUC=0.84). Results: The test area under the curve of the logistic
regression model was 0.72 with the 17 microbiome markers. When analyzed
by combining white blood cell count and cervical length, the random
forest model showed the test area under the curve of 0.84. The GUIDE
model confirmed that the association with preterm birth was high when
Prevotella and Ureaplasma increased, which could also be explained by
the fact that as the number of Peptoniphilus increased, the association
with preterm birth was higher. Conclusions: Our study demonstrates that
several candidate bacteria could be used as potential predictors for
preterm birth, and that the predictive rate can be increased through a
machine learning model employing a combination of cervical length and
white blood cell count information.
Political history of Croatia at the turn of the 19th–20th centuries: problems and methods
Authors: Dronov Aleksandr M.
Published: March 2022

The review analyzes the monograph by Croatian historian Branko Ostajmer Narodna stranka u Slavoniji i Srijemu 1883.–1903. [The People’s Party in Slavonia and Srem in 1883–1903] and considers the historiography, source base, structure, and content of the book. Not only does the author of the monograph contribute to the development of Croatian historiography, but he also polemicizes with his predecessors and contemporaries. The extant archival sources of the period studied by B. Ostajmer are not plentiful, so the book is largely based on periodicals. A specific feature of his work is the author’s focus on the outstanding personalities of the era associated with the activities of the People’s Party. In addition, it is necessary to highlight the author’s analysis of Slavonism, a concept that is important for understanding the period and the region under study. B. Ostajmer studies the internal organization of the party and its electorate, including the interaction with individual social and ethnic groups, as well as the activities of the party in the context of Croat-Hungarian relations. Much space in the narrative is given to the figure of Croatian Ban K. Khuen-Héderváry, whose reign was taken as the chronological framework of the work. The book can be of interest to historians of parties and social movements of the Modern Era as well as specialists in Croatia, the Balkans, and Central Europe.
Cebir Öğretiminde Gerçekçi Matematik Eğitimi Yaklaşımının Öğrenci Başarısına ve Kalıcılığına Etkisi
Authors: Özkan Melek , Aksoy Nuri Can , Çinar Cengiz
Published: March 2022

Bu araştırmanın amacı Gerçekçi Matematik Eğitimi ile 6. sınıf cebir öğretiminin, öğrencilerin akademik başarılarına ve kalıcılığa etkisini incelemektir. Araştırmada öntest-son test deney ve kontrol gruplu yarı deneysel desen kullanılmıştır. Çalışma, Bursa ilinde bulunan iki devlet ortaokulunda, 20 kişi deney ve 24 kişi de kontrol grubu olmak üzere 44 altıncı sınıf öğrencisiyle yürütülmüştür. Araştırmanın örneklemi rastgele örnekleme yöntemi kullanılarak oluşturulmuştur. Dersler, “Cebir” öğrenme alanında deney grubunda Gerçekçi Matematik Eğitimi yaklaşımı ile, kontrol grubunda ise Millî Eğitim Bakanlığı İlköğretim Matematik Dersi Öğretim Programı’nda yer alan mevcut öğretim yöntemi ile sürdürülmüştür. Araştırmada, Başarı Testi deney ve kontrol gruplarına ön test, son test ve kalıcılık testi olarak uygulanmıştır. Elde edilen ve normal dağılım gösteren veriler t testi ile analiz edilmiştir. Uygulama öncesi deney ve kontrol gruplarının aldıkları ön test puanları arasında anlamlı bir fark olmadığı görülmüştür. Araştırmadan elde edilen bulgulara göre, deney grubu öğrencilerinin akademik başarı düzeylerinin son test ve kalıcılık testlerinde, kontrol grubu öğrencilerine göre istatistiksel olarak anlamlı şekilde etkili olduğu bulunmuştur. Bu bağlamda cebir öğretiminde Gerçekçi Matematik Eğitimi’ne uygun etkinliklerin kullanılması önerilmektedir.
Anahtar Kelimeler: Gerçekçi matematik eğitimi; Akademik başarı; Cebir; Başarı; Kalıcılık.
Aquisição fonológica do Português Brasileiro
Authors: Pacheco Ribas Letícia , Faleiro Amanda , Sartori Bernardi Ana Carolina , Cerutti Lemmertz Maria Luiza
Published: March 2022

Introdução: O conhecimento sobre aquisição fonológica é balizador para a prática clínica na avaliação de transtornos fonológicos. Objetivo: Realizar revisão sistemática das publicações científicas sobre aquisição fonológica consonantal do Português Brasileiro (PB) por crianças com desenvolvimento linguístico típico. Metodologia: Foram selecionados descritores que atendiam à pergunta de pesquisa “qual a idade de aquisição fonológica consonantal típica de crianças falantes monolíngues do Português Brasileiro (PB)?” nas bases de dados Bireme, Pubmed, Scopus, Web of Science, Portal Periódicos Capes e Google Acadêmico, e literatura cinzenta. Critério de inclusão foi tratar-se de aquisição fonológica consonantal do PB por crianças. Excluíram-se estudos sobre aquisição de: vogais e/ou ditongos, domínios linguísticos que não fossem fonologia, segunda língua ou bilíngue, outra língua que não o PB, leitura, escrita, soletração, língua de sinais, também pesquisas somente com análise fonética, com dados de fala de crianças com alterações de fala, texto escrito, e linguagem não natural. Foram considerados os tipos de estudo, objetivos e indicadores de aquisição. Os estudos selecionados foram analisados via Iniciativa STROBE e Sistema GRADE. Resultados: Dos 1.381 estudos obtidos, selecionou-se 33. A aquisição fonológica consonantal foi identificada entre as idades um ano e quatro meses a sete anos, dependendo do fonema ou classe dos fonemas, apresentando grande variação entre indivíduos. A definição sobre aquisição convergiu para a frequência de 75% a 85% de produções corretas da consoante ou estrutura silábica. Conclusão: Constatou-se que a aquisição fonológica consonantal apresenta ampla variação entre indivíduos e entre diferentes consoantes e destas nas diversas estruturas silábicas.
Carbon Absorbing Vegetation and Enhancement of Ecosystem Benefits on Residential Environment
Authors: Jumiati Jumiati , Nugraheni Putranty Widha , Fitrianingsih Yulisa
Published: March 2022

With the increase in population, mainly in urban sprawls, the available vegetation decreases due to land conversion into the residential area. At the same time, the rise in population is proportional to the increase in air pollution, which is characterized by the Greenhouse Gases (GHG) problems. However, naturally, vegetation can absorb greenhouse gas emissions as a component in the photosynthesis process. Increasing space for housing is balanced with spatial regulations for the use of built-up land so that some of the carbon emissions from daily activities are reduced. Based on the research, there is still a difference between carbon absorption and carbon emissions; therefore, increasing the amount of vegetation as a Green Open Space (GOS) needs to be maximized based on the number and type of plants. The air pollution problem is attempted to be done naturally so that the ecosystem will naturally reduce the existing pollutants. The Community Service (CS) stages starting from land preparation, seed preparation, pathway construction, monitoring plantation, can be a solution to answer the problems of city dwellers on a housing scale. The overall implementation of the community services has gone well, such as constructing access pathways, planting trees and flower plants, and using land for public housing facilities into parks. The environment will be safer from wild and dangerous animals to create a better environment.
Research on the Countermeasures and Significance of Colleges and Universities based on the Current Situation of Labour Education of Contemporary College Students
Authors: Sun Liqin , Hu Yizhang
Published: March 2022

Labour is the cornerstone of the existence and development of human society, the common driving force of material civilization and spiritual civilization, and the source of the development and progress of human civilization. Incorporating Labour education into college teaching and combining it with ideological and political education is an important measure to improve college students' Labour ability, strengthen their will to Labour, and practice socialist Labour values. This research uses curriculum practice, questionnaire survey, media publicity, data analysis and other methods to take the students as the main body of the survey, and the Labour education course as the carrier to deeply understand the students’ daily Labour status, the preferences of course types, and individual Labour, concepts, external influencing factors and future course suggestions, fully realize the value of the course, and sublimate the meaning of the course.
Discussion on geothermal recovery process of deep borehole heat exchanger in layered stratum
Authors: Chen Feilong , Bai Yujie
Published: March 2022

To explore the characters of geothermal recovery process of deep borehole heat exchanger, a geothermal recovery process was simulated to explore the difference in stratum temperature distribution change under layered model and uniform model. The results indicated that the geothermal recovery rate is sharp at first and slow down then. The outlet temperature would be higher in the next heat extraction stage if the longer geothermal recovery period was adopted. Considering the time cost during the geothermal recovery period, the suggesting proportion of heat extraction and geothermal recovery could adopt 1:1. In addition, the uniform model cannot reveal the ground temperature variety of layered in geothermal recovery process accurately.
configuración del autor literario a lo largo de la historia
Authors: Ruiz Urbón Cristina
Published: March 2022

A pesar de que la conciencia autorial es connatural al ser humano, los escritores no han tenido siempre un reconocimiento social o una compensación económica por la producción de obras literarias y, menos aún, una protección jurídica. Tampoco han sido conscientes, hasta hace relativamente poco tiempo, de la unicidad de su escritura. En este trabajo ahondamos en las causas que han propiciado la configuración del autor literario a lo largo de la historia, primero como entidad social y, posteriormente y de forma gradual, como entidad profesional, jurídica e idiolectal; así como en su relación con la proliferación de textos anónimos, apócrifos, plagiarios, (auto)censurados o escritos bajo pseudónimo.
The Use of Payment Technology Through Financial Literacy
Authors: Estisia Pratiwi Rizka , Saefullah Kurniawan
Published: March 2022

Payment technology has dominated the fintech sector in Indonesia. Optimizing the use of payment technology requires encouragement in the development of financial literacy. Indonesia still has a low level of financial literacy compared to financial inclusion in Indonesia. The low level of financial literacy will lead to abuse of the use of fintech products and services. This study aims to see the effects of financial literacy on payment technology adoption using the TAM approach in urban cities in Indonesia, Jakarta Raya, Bandung, D.I. Yogyakarta, Semarang and Surabaya. The result demonstrates that financial literacy not an essential factor in adopting payment technology in Indonesia.
Methodological Paradigm of Non-Classical Science
Authors: GALUKHIN Andrey , MALAKHOVA Elena , PONIZOVKINA Irina
Published: March 2022

Scientific theories and methods developed within the framework of quantum and relativistic physics are the most representative paradigmatic instantiations of non-classical science. The profile of non-classical science is exposed through the analysis of a set of epistemic ideals and methodological principles. The adoption of the principle of operational relativity of phenomenal descriptions showed that a reference to the means of observation had become an intrinsic part of scientific description strategies. The transformation of the concept of objectivity can be seen in a specific combination of operationalism with interactional phenomenalism and constructivism. The introduction of the principle of complementarity marked the deviation from the standards of a monologic and linear description of the objects under study. This principle provides the operational basis for the integration of different parts of our knowledge with regard to non-trivial cognitive situations featured by the indeterminacy relations. Another prominent methodological trend is the reconsideration of the value of strict deterministic explanation strategies in favour of probabilistically oriented approaches. Scientists have encountered a new class of regularities that are typically analysed in terms of various types of statistical and non-causal determination. Nevertheless, it would be wrong to assume that any probabilistic account of natural phenomena implies indeterminism.