bluuebunny/crossref_metadata_2025 huggingface dataset:
N-fertilizer Postponing Application Improves Dry Matter Translocation and Increases System Productivity of Wheat/Maize Intercropping
Authors: Xu Ke , Chai Qiang , Hu Falong , Fan Zhilong , Yin Wen
Published: July 2021

Intercropping increases the grain yield to feed the ever-growing population in the world. It has been proven that N-fertilizer postponed topdressing can boost the productivity of cereal/legume intercropping. However, whether the application of this technology to cereal/cereal intercropping can still increase grain yield is unclear. A field experiment was conducted from 2018 to 2020 in the arid region of northwestern China to investigate the accumulation and distribution of dry matter and yield performance of wheat/maize intercropping in response to N-fertilizer postponed topdressing approaches. Allocations that were subjected to topdressing at the jointing and 15 d post-silking stages using the amount of nitrogen fertilizer (N3) that is traditionally used for maize production used only 30% and 10% of the total amount nitrogen, respectively. The allocations of postponed topdressing treatments of the two N fertilizers at these two stages were 10% and 30% for N1, and 20% and 20% for N2. The results showed that the postponed topdressing N fertilizer treatments boosted the maximum average crop growth rate (CGR) of wheat/maize intercropping. The N1 and N2 treatments increased the average maximum CGR by 32.9% and 16.4% during the co-growth period, respectively, and the second average maximum CGR was increased by 29.8% and 12.6% during the maize recovery growth stage, respectively, compared with the N3 treatment. The N1 treatment was superior to other treatments, since it increased the CGR of intercropped wheat during the co-growth period and accelerated the CGR of intercropped maize after the wheat had been harvested. This treatment also increased the biomass and grain yield of intercropping by 8.6% and 33.7%, respectively, compared with the current N management practice. This yield gain was primarily attributable to the higher total translocation of dry matter. The intercropping system increased the translocation of dry matter to grain in vegetative organs, while the N fertilizer postponed topdressing promoted this effect. Therefore, the harvest index of intercropped wheat and maize with N1 was 5.9% and 5.3% greater than that of N3, respectively. This demonstrated that optimizing the management of N fertilizer can increase the grain yield from wheat/maize intercropping via the promotion of accumulation and translocation of dry matter.
Development of a real-time RT-PCR assay for the detection of pan-human parechoviruses
Authors: Lu Huanhuan , Xiao Jinbo , Zhang Keyi , Han Zhenzhi , Song Yang , Wang Dongyan , Ji Tianjiao , Yan Dongmei , Zhu Shuangli , Xu Wenbo , Zhang Yong
Published: July 2021

Background
Parechoviruses (PeV-As), which constitute a new genus within the family Picornaviridae, have been associated with numerous localized outbreaks of serious diseases, such as coryza, pneumonia, maculopapular exanthem, and conjunctivitis. However, only a few laboratories worldwide routinely conduct tests for the identification of this group of viruses; presently, to the best of our knowledge, no laboratory in China conducts routine test for PeV-A identification. Therefore, in this study, we aimed to develop and validate a real-time RT-PCR assay for the identification of PeV-As.
Methods
To designed and validate a real-time PCR primer-probe targeting the 5′-UTR region of PeV-As, the 5′-UTR sequences of PeV-As available in GenBank were aligned using the MUSCLE algorithm in MEGA v7.0. Thereafter, the highly conserved 5′-UTR region was selected, and its primer-probe sequence was designed using Primer Premier v5.0. This primer-probe sequence was then evaluated for specificity, sensitivity, and repeatability, and for its validation, it was tested using fecal samples from 728 healthy children living in Beijing (China).
Results
The PeV-A real-time RT-PCR assay detected only the RNA-positive standards of PeV-A genotypes (1–8, 14, 17, and 18), whereas 72 serotypes of non-PeV-A EV viruses were undetected. In addition, the VP1 region of these 11 PeV-A genotypes that tested positive were amplified using the primers designed in this study. Typing results indicated that eight, one, and two strains of the 11 were PeV-A1, PeV-A4, and PeV-A6, respectively. We also determined and presented the genetic characterization and phylogenetic analyses results corresponding to these 11 VP1 region sequences. Furthermore, the real-time RT-PCR assay showed good repeatability, reproducibility, and sensitivity.
Conclusion
Our findings suggested that the real-time RT-PCR assay developed in this study can be applied for routine PeV-A identification. Additionally, we believe that our results will serve as a foundation for further studies on PeV-As and facilitate the expansion of the gene sequence information available in GenBank.
Comparison of Efficacy Between Steroid Therapy and Observation Therapy in the Treatment of Traumatic Optic Neuropathy-a Meta-analysis
Authors: Zhang Peipei , Xue Chao , Chen Ying , Su Xuening
Published: July 2021

Background: Until now, the exact pathophysiology of traumatic optic neuropathy(TON) is still unclear, its management has remained controversial. The effect of steroid in TON remains unclear. The purpose of this study is to compare the effect of steroid therapy with observation therapy in the treatment of traumatic optic neuropathy(TON). Methods: A systematic literature search was performed in data sources including CENTRAL, PubMed, EMBASE, Web of Science, Cochrane Library, MEDLINE, Chinese databases including Wanfang and China National Knowledge Infrastructure for to find relevant studies. The statistical analysis was performed by RevMan 5.3 software.Results: Eight studies including 263 eyes were enrolled in this study. The rate of improvement of VA in the steroid group was not better than that of the observation group (OR=2.17, 95%, CI=1.23-3.83, P=0.007), with no heterogeneity (I2=0,P=0.43).Conclusions: Patients with TON receiving steroid treatment may not have a better visual recovery than observation therapy. Steroid therapy is not recommend in patients with TON. Further larger randomized clinical trials are needed to evaluate the effect of steroid therapy for TON in the future.
Single-crystalline TiO2 Nanoparticles for Narrowing the Scalability Gap towards Stable and Efficient Perovskite Modules
Authors: Ding Yong , Ding Bin , Kanda Hiroyuki , Usiobo Onovbaramwen Jennifer , Gallet Thibaut , Yang Zhenhai , Liu Yan , Huang Hao , Sheng Jiang , Liu Cheng , Yang Yi , Queloz Valentin , Zhang Xianfu , Audinot Jean-Nicolas , Redinger Alex , Dang Wei , Mosconi Edoardo , Luo Wen , De Angelis Filippo , Wang Mingkui , Wu Jihuai , Yang GuanJun , Dai Songyuan , Dyson Paul , Nazeeruddin MOHAMMAD KHAJA
Published: July 2021

Remarkable progress in power conversion efficiency of perovskite solar cells (PSCs) has been achieved over the last decade, reaching 25.5%. However, transferring these accomplishments from individual small-size devices into large-area modules while preserving their commercial competitiveness compared to other thin-film solar cells remains a challenge. A major obstacle is to reduce the resistive losses and the number of intrinsic defects of electron transport layers (mesoporous TiO2, ETL) and to fabricate high-quality large-area perovskite films. Here, we report a facile solvothermal method to synthesize single-crystalline TiO2 rhombus-like nanoparticles with exposed {001} facets. Owing to their low lattice mismatch with the perovskite absorber, high electron mobility and lower density of defects, single-crystalline TiO2 nanoparticle-based small-size devices (0.09 cm2) achieve an efficiency of 24.05% and a fill factor of 84.7%. Importantly, these devices maintain about 90% of their initial performance after continuous operation for 1400 h. Combined with vacuum quenching-assisted techniques, we have fabricated large-area modules and obtained a certified efficiency of 22.72% with an active area of nearly 24 cm2. This represents the highest efficiency modules with the lowest efficiency loss between small-size devices and modules, enabling to reproducibly fabricate stable and efficient PSC modules.
Clinical Outcome and Risk Factors for Acute Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation: an Analysis of Nationwide CSECLS Database in China Mainland
Authors: Hao Tong , Jiang Yu , Wu Changde , Li Chenglong , Chen Chuang , Xie Jianfeng , Pan Chun , Guo Fengmei , Huang Yingzi , Liu Ling , Xie Haixiu , Du Zhongtao , Hou Xiaotong , liu Songqiao , Yang Yi , Qiu Haibo
Published: July 2021

Purpose: To assess the outcomes and risk factors for adult patients with acute fulminant myocarditis supported with venoarterial extracorporeal membrane oxygenation (VA ECMO) in China mainland. Methods: Data were extracted from Chinese Society of ExtraCorporeal Life Support (CSECLS) Registry database. Data from adult patients who were diagnosed with acute myocarditis and needed VA ECMO in the database were retrospectively analyzed. The primary outcome was 90-day mortality after ECMO initiation in patients with acute fulminant myocarditis supported with VA ECMO. Cox proportional hazard regression model was used to examine the risk factors associated with 90-day mortality. Results: Among 221 patients enrolled, 186 (84.2%) patients weaned from ECMO and 159 (71.9%) patients survived to 90 days. The median age was 38 years (IQR 29-49) and males (n=115) accounted for 52.0% of the patients. The median ECMO duration was 134 hours (IQR 96-177hrs). The main adverse events during ECMO course was bleeding (16.3%), followed by infection (15.4%). In the multivariate Cox model, cardiac arrest prior to ECMO initiation (adjusted HR 2.529; 95%CI: 1.341-4.767, p =0.004), lower pH value (adjusted HR 0.016; 95%CI: 0.010-0.059, p <0.001) and higher lactate concentration at 24 hours after ECMO initiation (adjusted HR 1.146; 95%CI: 1.075-1.221, p <0.001) was associated with 90day mortality. Conclusions: In our study, 71.9% patients with acute fulminant myocarditis supported with VA ECMO survived to 90 days. Cardiac arrest prior to ECMO, lower pH and higher lactate concentration at 24 hours after ECMO initiation were correlated with 90-day mortality closely.ClinicalTrials.gov registration number: NCT04158479, Registered 8 November 2019, https://clinicaltrials.gov/ct2/show/NCT04158479?term=hou+xiaotong&draw=2&rank=2.
Whispering of the city: Characteristics and origin of environmental shaking in the Taipei metropolitan area
Authors: Chen Kate Huihusan , Yeh Ting-Chen , Johnson Christopher W. , Chen Yaochieh , Lin Cheng-Horng , Lai Ya-Chuan , Shih Min-Hung
Published: July 2021

Examining continuous seismic data recorded by a dense broadband seismic network throughout Taipei shows for the first time, the nature of seismic noise in this highly populated metropolitan. Using 140 broadband stations in a 50 km x 69 km area, three different recurring, strong noise signals characterized by dominant frequencies of 2–20 Hz, 0.25-1 Hz, and < 0.2 Hz are explored. At frequencies of 2–20 Hz, the seismic noise exhibits daily and weekly variations, and a quiescence during the Chinese New Year holidays. The largest amplitude occurred at a station located only 400 m from a traffic-roundabout, one of the busiest intersections in Taipei, suggesting a possible correlation between large amplitude with traffic flow. The median daily amplitude for the < 0.2 Hz and 0.2-1.0 Hz frequency bands are mostly synchronized with high similarity between stations, indicating that the sources are persistent oceanic or atmospheric perturbations across a large area. The daily amplitude for the > 2 Hz band, however, is low, indicating a local source that changes on shorter length scales. Human activities responsible for the 2–40 Hz energy in the city, we discovered, are able to produce amplitudes approximately 2 to 1500 times larger than natural sources.
Genetic and non-genetic parameters for growth traits and Kleiber ratios in Dorper x indigenous sheep
Authors: Tesema Zeleke , Deribe Belay , Lakew Mesin , Getachew Tesfaye , Tilahun Mekonnen , Belayneh Negus , Kefale Alemu , Shibesh Mekonnen , Zegeye Asres , Yizengaw Liuel , Worku Getachew , Tiruneh Solomon , Kiros Shanbel , Asfaw Mengesha , Bishaw Molla
Published: July 2021

Genetic improvement program will only be successful when accompanied by a good understanding of the influence of environmental factors, knowledge of the genetic parameters, and the genetic relationships between the traits of interest. Thus, this study aimed to evaluate the influence of non-genetic factors on growth traits and Kleiber ratios and to estimate genetic parameters for early growth traits in Dorper x indigenous sheep. The effects of fixed factors were analyzed by the general linear model procedure of SAS and the genetic parameters were estimated by AI-REML algorithm using a WOMBAT computer program fitted animal model. The log-likelihood ratio test was used for selecting the best-fitted model from four models. The overall least-squares means for birth weight (BW), weaning weight (3MW), six-months (6MW), nine-month (9MW), and yearling (12WT) were 3.03 ± 0.02, 14.5 ± 0.18, 20.4 ± 0.26, 24.8 ± 0.31, and 28.3 ± 0.40 kg, respectively. The overall least-square means for Kleiber ratio from birth to weaning (KR1), weaning to six-month (KR2), six to nine-month (KR3) and nine-month to yearling age (KR4) were 16.8 ± 0.10, 6.41 ± 0.17, 4.55 ± 0.21 and 3.38 ± 0.20 g/kg of metabolic weight, respectively. The inclusion of maternal genetic effect exerted a significant influence on BW and it explains 20% of the phenotypic variation. The total heritability (h2t) estimates for BW, 3MW, ADG1 and KR1 were 0.10, 0.14, 0.16 and 0.12, respectively. The phenotypic correlation varied from − 0.11 to 0.98 whereas the direct genetic correlation ranged from − 0.32 to 0.98. The mean inbreeding coefficient was 0.105% with annual rate of 0.02%. The heritability estimates for growth traits and Kleiber ratio suggests that slow genetic progress would be expected from the selection. However it is, integration of selection with crossbreeding program with this level of variation would enhance the genetic gain. Therefore, selection should be conducted based on breeding values estimated from multiple information sources to increases the selection response.
Liver endothelium promotes HER3-mediated cell survival in KRAS wild-type and mutant colorectal cancer cells
Authors: Rathore Moeez , Wright Michel'le , Bhattacharya Rajat , Fan Fan , Vaziri-Gohar Ali , Winter Jordan , Wang Zhenghe , Markowitz Sanford , Willis Joseph , Ellis Lee , Wang Rui
Published: July 2021

We previously showed that human epidermal growth factor receptor 3 (HER3, also known as ERBB3) is a key mediator in liver endothelial cell (EC) promoting colorectal cancer (CRC) growth and chemoresistance, and suggested HER3-targeted therapy as a strategy for treating patients with metastatic CRC (mCRC) in the liver. Meanwhile, KRAS mutations occur in 40–50% of mCRC and render CRC resistant to therapies targeting the other HER family protein epidermal growth factor receptor (EGFR). It is necessary to elucidate the roles of KRAS mutation status in HER3-mediated cell survival and CRC response to HER3 inhibition. In the present study, we demonstrated that liver EC-secreted factors activated HER3 and promoted cell survival in KRAS wild-type and mutant CRC cells and tumors, and that blocking HER3 with an antibody, seribantumab, blocked EC-induced CRC survival. Our findings highlight a potential of utilizing HER3-targeted therapies for treating patients with mCRC regardless of KRAS mutation status.
Substantiation of the parameters of open stoping mining method with abandonment of unrecoverable pillars
Authors: Antipin Iurii
Published: July 2021

Relevance. Developing inclined ore bodies of low and uneven thickness using mining systems with caving results in great losses and dilution, deteriorating the conditions for ore gravitation. As a consequence, it becomes necessary to slice the barren rock in the lying side to form slopes with the desired angle. There are also characteristic ore losses at the dead end of the drawing drift independent of the ore body thickness, therefore acquiring a significant role under a lesser thickness. The height of the sublevels, limited by the ore body’s inclination, leads to a considerable amount of preparatory and development operations. The absence of actual in-process monitoring of useful component content in the ore drawing doses often leads to increased dilution rates due to the drawing of barren caved rocks of the previously worked overlying sublevel. Thus, the technological solutions search and their design parameters substantiation for the conditions of inclined ore bodies of low thickness is an urgent scientific and technical problem. Research aim is to substantiate the parameters of the open stoping mining which provides for leaving unrecoverable pillars which ensure the drawing of the maximum volume of pure ore under the cantilever of the hanging side rocks. Research methods. The work used a comprehensive research method based on search and design of technically rational options for geotechnology, their technical and economic assessment and mathematical modeling, and determination of stable parameters of mining system structural elements – the chamber span and the pillar width. Results analysis. The optimal variant of the open stoping mining system has been determined. In comparison with the basic technology of sublevel caving, the specific consumption of preparatory and development operations per 1000 tons of mined ore has been reduced by 34%, the cost of mined ore – by 12%, and ore losses and dilution – by 2 and 2.9 times, respectively. The stable parameters of the chamber span and pillar width have been established. Conclusions. The developed technology of sublevel open stoping with double chambers with frontal ore drawing using remote-controlled loading and hauling machines and subsequent caving of unrecoverable pillars of minimum width allows to significantly increase the efficiency of mining.
Substantiation of process schemes of field development taking into account technogenic conversion
Authors: Mazhitov Artur
Published: July 2021

Introduction. Mining disturbs the natural state of the rock mass. Besides, the field reserves are of a different degree and nature of man-induced changes, which directly affects mining prime cost and ore marketable value. The scientific and practical relevance of the research consists in ensuring increased completeness and economic efficiency of field development by applying the development systems of different classes and taking into account the man-induced changes in reserves in mining dynamics. Research aim is to substantiate the technological schemes of mining, that take into account the possibility and feasibility of developing the reserves which have been affected by the man-induced changes, in particular when switching from one class of development systems to another. Research methods. In this research, based on the analysis of the mining and geological conditions of copper sulfide deposits, economic and mathematical modeling of developing an ore deposit by development systems of different classes was carried out, and the man-induced changes in underground reserves in the process of mining were taken into account. Results. Based on the modeling results, it was found that the increase in the economic efficiency of the deposit development is provided by justifying the type, sequence, and limits of applying different geotechnologies related to different classes of development systems within the entire deposit and a separate ore body. Conclusion. The research results can be used when designing fields in terms of selecting and substantiating the applied development systems.
Stavovi nastavnika geografije o radu s učenicima s teškoćama u razvoju
Authors: Svilan Dominko , Pejdo Ana , Brkić-Vejmelka Jadranka
Published: July 2021

Za uspješnu primjenu koncepta inkluzivnog obrazovanja, uz materijalne i tehničke uvjete, vrlo je važna kvaliteta i unapređenje odgojno obrazovne prakse, temeljna znanja o odgoju i obrazovanju djece s teškoćama, kao i kompetentnost svih dionika u procesu odgoja i obrazovanja. Nastavnici su ključni dio odgojno-obrazovnog procesa pa su njihova stečena znanja i vještine od velike važnosti za uspjeh primjene koncepta inkluzivnog obrazovanja. Cilj ovoga rada bio je utvrditi stavove nastavnika geografije osnovnih i srednjih škola o radu s učenicima s teškoćama u razvoju te analizirati koje nastavne metode koriste i u kojoj mjeri ih prilagođavaju učenicima s teškoćama u razvoju. Istraživanje je provedeno metodom anketnog upitnika, a obuhvatilo je nastavnike osnovnih i srednjih škola u Hrvatskoj (N=110). Rezultati istraživanja pokazuju da se nastavnici ne smatraju dovoljno kompetentnima za svakodnevni rad s djecom s teškoćama te izražavaju potrebu za dodatnim edukacijama i usavršavanjima. U svakodnevnom radu nastoje prilagoditi nastavne sadržaje i metode poučavanja pojedinim teškoćama djece. Nastavnici smatraju kako je za uspjeh u poučavanju potrebna veća suradnja sa školskom stručno-pedagoškom službom i s roditeljima. Kod pojedinih tvrdnji utvrđene su razlike u stavovima nastavnika koji rade u osnovnim u odnosu na one zaposlene u srednjim školama.
Analiza primjene nastavnih strategija u visokoškolskoj nastavi umjetničkog područja
Authors: Radočaj-Jerković Antoaneta , Škojo Tihana
Published: July 2021

U radu je prikazano istraživanje koje je bilo provedeno s ciljem analize primjene nastavnih strategija – metoda i postupaka, oblika rada na nastavi, kao i postupaka vrednovanja i ocjenjivanja studentskih postignuća – na jednom većinski umjetničkom visokom učilištu u sastavu javnog sveučilišta s područja Republike Hrvatske. Iz rezultata istraživanja razvidno je da je visokoobrazovna nastava oblikovana na suvremenim didaktičkim načelima s dominantnom paradigmom nastave usmjerene na studenta u kojoj se studente potiče na preuzimanje aktivne uloge u procesu učenja. Također, procesi poučavanja u umjetnosti su individualizirani, a praćenje rada i vrednovanje napretka studenata sustavno. Uočeno je da u umjetničkoj nastavi postoji određena terminološka nedosljednost u korištenju pojedinih didaktičkih pojmova jer je visokoškolska umjetnička nastava preuzela tradicionalnu didaktičku terminologiju prikladniju oblikovanju nastave u znanstvenom području. Kroz dobivene rezultate aktualizirana je potreba za pojmovnim redefiniranjem u kojemu bi se istaknule i objasnile specifičnosti koje proizlaze iz prirode umjetničkog procesa, a povezane su sa specifičnostima svakog pojedinog umjetničkog polja. Dobiveni rezultati otvaraju uvid u pojedine prednosti i nedostatke umjetničke visokoškolske nastave. Osim boljem razumijevanju umjetničke nastave, oni mogu doprinijeti i budućem sistematiziranju nastavnoga rada na umjetničkim fakultetima, osobito u dijelu koji se odnosi na organizaciju i vrednovanja kvalitete nastavnoga procesa.
Vaccine containing immunologic adjuvants with a wide range of activity to provide protection against COVID-19
Authors: Berhanu Mulugeta
Published: July 2021

This paper proposes a wide spectrum immunologic adjuvant for vaccine development against  COVID-19 which is the current global problem. It has been reported that a wide range of immune cells are involved in the body’s response to SARS CoV2 infection. Therefore, vaccine with a wide-spectrum immunologic adjuvant can be used to provide protection against COVID-19. Lack of adjuvants that can induce the required immune responses is a serious impediment to vaccine development against this devastating virus. The approved adjuvants such as aluminum salts and MF59 exhibit a narrow range of activity. In an attempt to solve this problem, it is crucial to develop new adjuvants which can trigger a wide range of immune cells.
Transhumanismo, pregunta a la naturaleza humana
Authors: Fernández Valdés Giovanni
Published: July 2021

El transhumanismo como filosofía e ideología tecnologicista tiene cada vez más adeptos y se coloca en los ámbitos académicos como una posición positiva, posible y deseable. Su implementación aparece solapada en una vida cotidiana que depende, como nunca antes, de los avances tecnológicos. La posición que manejaremos es que esta ideología, que sobredimensiona el papel de la tecnología en la sociedad, tiene una visión limitada respecto con los conflictos éticos, económicos y sociales que dimanan de sus presupuestos. El problema no es negar la tecnología sino qué rol juega en la construcción de la sociedad. El transhumanismo puede estar vendiendo un falso sueño de libertad, donde la uniformidad, la ausencia de crítica, la discriminación y la separación radical entre pobres y ricos definan ese mundo paradisíaco que propone.
The 2020 Reform of the Water and Sanitation Services Sector in Brazil
Authors: Nunes C. M. , Anderaos A. A. , Marinho de Araujo Cintia Leal
Published: July 2021

With over 100 million people without access to sewage collection and treatment and over 35 million lacking access to piped drinking water, the water and sanitation services (WSS) sector in Brazil ranks last among all the infrastructure sectors. Despite previous efforts to reach universal coverage, the gap remains wide. In order to reduce this gap, the Brazilian Parliament approved the reform of the WSS sector in July 2020. This paper examines the state of the water and sanitation services in Brazil before 2020 as well as the potential effects of the recently approved reform. It demonstrates that the sector’s primary issues are the fragmented institutional arrangements and regulations, the low levels of investments by the public sector, including those made by State-owned water companies, and the barriers to entry for the private sector. The paper also discusses the new provisions included in the reform designed to remedy those issues. The authors believe that the reform has the potential to promote significant changes in the structure of the WSS towards providing a universal and equitable service in Brazil, but at a slower pace than the reformers anticipated.
Renewable Energy in Russia: System Analysis of Barriers
Authors: Ljovkina A. , Brody M. , Karagulyan E. , Zakharova A , Ljovkin V.
Published: July 2021

Considering the current ecological situation in the modern world, the quality of life depends not so much on a stable energy supply as on an environmentally friendly way of producing and consuming energy, which has turned social and research attention to the opportunities of renewable energy systems (RES). In spite of the vital necessity of transitioning to environmentally friendly energy production, the implementation and development of renewable energy technologies face a range of barriers: socio-cultural, technological, economic, institutional and environmental. To overcome these barriers, the authors of this article use the systems approach to gain deeper understanding of RES interconnection and interdependence. They apply STEEP analysis for classification and qualitative analysis of RES development barriers in Russia. The article proposes the analytical methodology, which reveals system specifications of the national RES development barriers and predicts the chain reaction of overcoming particular barriers. Using this methodology, the authors identify the main socio-cultural roots of RES development barriers in Russia: state control of the development of the energy sector, the political stake in hydrocarbons and the lack of consistent policies on RES development. The authors’ suggested analysis methodology is appropriate for identifying the root problems in energy socio-economic systems and for effective decision-making process in the energy sector.
A Participação popular no processo decisório da Agência Nacional de Saúde Suplementar
Authors: Leurquin Pablo , Manacés Renato
Published: July 2021

O presente trabalho tem como objetivo analisar a participação popular no processo decisório da Agência Nacional de Saúde Suplementar (ANS). Para tanto, adota-se como metodologia a pesquisa bibliográfica realizada em parte da doutrina brasileira constitucional e administrativa, bem como a pesquisa documental de dados elaborados pelo IPEA e de relatórios extraídos do sítio eletrônico da ANS. Parte-se da hipótese de que há um déficit de legitimidade democrática no que tange à participação da sociedade na tomada de decisões de tal autarquia. Ancorou-se em autores que abordam o assunto sob uma perspectiva crítica, colocando em evidência os problemas de se considerar os meios participativos enquanto ferramentas formais. Assim, conclui-se apontando o paradoxo de um modelo que se pretende participativo, mas que, na verdade, acaba por ser tomado pelas operadoras dos planos de saúde.
Protagonismo juvenil: reflexões jurídico-filosóficas acerca da participação das juventudes no agir político contemporâneo
Authors: Santos Cristiano Lange dos
Published: July 2021

O objetivo é refletir sobre a concepção que envolve o protagonismo juvenil, a participação e o agir das juventudes no campo da política. O problema é examinar o descompasso entre os conteúdos jurídicos dispostos no Estatuto da Juventude que garantem a participação dos jovens - em sua dimensão de protagonismo - e a sua efetiva aplicação no campo da política. A hipótese é que há um distanciamento entre as normas previstas no Estatuto da Juventude, que garantem os jovens como sujeitos de direitos e a sua inserção nos espaços políticos de participação, para considerá-los como protagonistas, capazes de assumir uma ação com caráter emancipatório no campo da política. O método de procedimento é monográfico, com técnicas de pesquisa bibliográfica e documental. Conclui-se que o protagonismo juvenil se limitou a exercer uma dimensão pedagógica, vinculada ao âmbito escolar, incapaz de afirmar os jovens enquanto sujeitos de direitos, capazes de fortalecer a cidadania e politização nos processos de participação política.
La desproporcionalidad de Derechos por la desnaturalización del plazo razonable en la atención de un conflicto familiar ju
Authors: Sierra-Zamora Paola Alexandra , Tapia Manuel Bermúdez
Published: July 2021

El desarrollo de los conflictos familiares que se judicializan generan un inconveniente que se amplifica en el ámbito del trámite judicial en la especialidad de familia, especialmente porque el tiempo genera una distorción de derechos que desnaturaliza el concepto de dignidad entre las partes que intervienen en el proceso y en el mismo conflicto familiar que en forma derivada provoca que los sujetos de derechos partícipes en dicho proceso judicial no tengan una condición de “igualdad” material, siendo esta situación negativa invisible al sistema judicial. El texto tiene una metodología descriptiva y analítica de la realidad judicial nacional, delimitándose al ámbito jurisdiccional en la especialidad de familia.
Os Papas na ONU e a defesa dos Direitos Humanos
Authors: Ribeiro Raphael Rego Borges
Published: July 2021

Neste artigo, analisamos as manifestações dos Papas endereçadas à Assembleia Geral das Nações Unidas, buscando nelas identificar elementos de defesa dos Direitos Humanos. Recorremos à consulta a fontes primárias, especificamente os discursos de Paulo VI, João Paulo II, Bento XVI e Francisco à ONU. Utilizamos o método dedutivo para conduzir nossa análise. Tivemos como objetivo geral verificar se a Igreja Católica assumiu publicamente, à comunidade internacional, uma postura de defesa da humanidade. Observamos que todos os Papas abordaram diversos temas de Direitos Humanos. Notamos que Paulo VI e João Paulo II focaram na promoção da paz, no combate à pobreza e na proteção à liberdade religiosa. Também percebemos que Bento XVI e Francisco, além de defender os tópicos trazidos pelos seus antecessores, também advogaram pela preservação ambiental.
Effect of Prenatal Yoga on Duration of the First Stage of Labor and Perineal Rupture in Primigravida Mothers
Authors: Daniyati Asri , Mawaddah Shohipatul
Published: July 2021

In primigravidas, the first stage of labor has a longer duration than multiparous. The first stage of labor in primiparous is around 13-14 hours, while in multiparous it is about 7 hours. Prolonged labor is one of the causes of maternal death. Yoga in pregnancy can maintain elasticity and strength of the ligaments of the pelvis, hips, and leg muscles, so that it can reduce pain during labor and provide space for the birth canal. The comparative analytical research method used pre-experimental design with the one shot case study design. With a sample of 26 trimesters III primigravida pregnant women who were divided into 2 groups, namely n = 13 groups who did prenatal yoga, and n = 13 groups who did not do prenatal yoga. The analysis of this research was univariate and bivariate using the Mann Whitney test. Assessment is carried out during the delivery process. As a result, the intervention and control groups with active phase I labor duration obtained p = 0.000, and perineal rupture p = 0.000. There was a significant difference in the length of the first stage of labor and perineal rupture between the yoga group and the non-yoga group. Prenatal yoga affects the duration of the first stage of labor and perineal rupture.
INTERPRETATIONS OF THE PHILOSOPHICAL LEGACY OF VOLODYMYR SHYNKARUK IN THE WORKS OF VITALII TABACHKOVSKYI
Authors: VOVK ANATOLIJ
Published: July 2021

The emergence of various interpretations of the legacy of Volodymyr Shynkaruk is caused not only by the texts of the classic of modern Ukrainian philosopher and facts from the histo-ry of philosophical thought development in Ukraine in the second half of the 20th century, but also by the struggle of various narratives that already exist or are offered by philosophers to tell about the fate of philosophy in Kyiv in Soviet and post-Soviet times. The discussion about the identity of Volodymyr Shynkaruk's philosophy arose in the late 1990s and early 2000s in connection with the publication by V.H. Tabachkovskyi of a number of articles and chapters in books devoted to the interpretation of the figure of V. Shynkaruk as the founder of the Kyiv anthropological school. Vitalii Tabachkovskyi tried to substantiate and reveal a cer-tain narrative about the Kyiv Philosophical School as the central mainstream in the philo-sophical sixties, as well as a narrative about the phenomenon of philosophical sixties as a kind of manifestation of liberalism and dissidence regarding the official ideology and philos-ophy. Many distortions of the true meaning of the texts of Kyiv philosophers occurred through reading them not in their own context and meanings, but through guessing what similar philosophical concepts are in world thought. Vitalii Tabachkovskyi's method of anal-ogies and his attempts to look at Volodymyr Shynkaruk's work through the prism of analo-gies with modern trends develop in his book and many articles. Despite the desire to posi-tively accept Vitalii Tabachkovskyi's reasoning about Volodymyr Shynkaruk's philosophical views, we cannot do this, as his reflections at certain points obviously contradict Volodymyr Shynkaruk's texts.
Параметры контура линий водяного пара при уширении гелием
Authors: Лаврентьева Н.Н. , Дударёнок А.С.
Published: July 2021

The averaged energy difference method has been applied to calculate the broadening coefficients of rotation vibration water vapor lines induced by helium pressure. The calculations have been performed for a wide range of rotational quantum numbers (the averaged energy difference method have been applied for J from 0 to 20, interpolation of the J-dependence have been used for J from 20 to 50) in the spectral range from 500 to 10000 cm-1. We compared the calculated H2O-He line broadening coefficients with the literature data, and a good agreement have been obtained. The temperature dependence for linewidths are calculated.
Aislamiento, identificación y evaluación de levaduras con potencial probiótico in vitro provenientes del suero de queso Paipa
Authors: López Barreto Ricardo Enrique , Becerra Jiménez Mónica Liliana , Balaguera- López Helber Enrique , Chaparro Acuña Sandra Patricia , Borrás Sandoval Luis Miguel
Published: July 2021

El objetivo de este trabajo fue aislar e identificar levaduras del lactosuero del queso Paipa y evaluar su potencial probiótico (in vitro) para su uso en alimentación animal. Las cepas se aislaron en caldo extracto de levadura-glucosa-cloranfenicol, se purificaron en agar PDA y se caracterizaron molecularmente. Se aislaron 10 cepas dentro de las que se encuentran Candida kefyr, Kluyveromyces marxianus, Pichia fermentans, entre otras. Las levaduras aisladas fueron evaluadas para evidenciar su uso potencial como probióticos en alimentación animal. Se determinó la resistencia a sales biliares (0,05, 0,1, 0,15, 0,20, 0,25 y 0,30 %), la estabilidad al pH del estómago (1,5, 2,0, 2,5, 3,0, 3,5 y 4,0) y resistencia al jugo gástrico (pH 1,5, NaCl de 0,2 % y pepsina de 0,32 %). En la prueba con diferentes concentraciones de sales biliares, las mejores cepas fueron K. marxianus (30_4) y P. fermentans (28_5). En la prueba de pH, el mejor desempeño lo tuvieron P. marxianus (30_4) y Yarrowia lipolytica. Finalmente, en la prueba de jugos gástricos se destacaron C. kefyr y K. marxianus (R_1). Las cepas que presentaron buen desempeño en casi todas las pruebas fueron K. marxianus (30_4) y P. fermentans (28_5), de tal forma que estas levaduras aisladas del lactosuero de queso Paipa tienen potencial en la aplicación como probióticos en la alimentación animal.
A Web-Based Integrated Management Program for Improving Medication Adherence and Quality of Life, and Reducing Readmission in Patients With Atrial Fibrillation: Randomized Controlled Trial
Authors: Hsieh Hui-Ling , Kao Chi-Wen , Cheng Shu-Meng , Chang Yue-Cune
Published: July 2021

Background

Atrial fibrillation (AF) is related to a variety of chronic diseases and life-threatening complications. It is estimated that by 2050, there will be 72 million patients with AF in Asia, of which 2.9 million will have AF-associated stroke. AF has become a major issue for health care systems.

Objective

We aimed to evaluate the effects of a web-based integrated management program on improving coping strategies, medication adherence, and health-related quality of life (HRQoL) in patients with AF, and to detect the effect on decreasing readmission events.

Methods

The parallel-group, single-blind, prospective randomized controlled trial recruited patients with AF from a medical center in northern Taiwan and divided them randomly into intervention and control groups. Patients in the intervention group received the web-based integrated management program, whereas those in the control group received usual care. The measurement tools included the Brief Coping Orientation to Problems Experienced (COPE) scale, Medication Adherence Rating Scale (MARS), the three-level version of the EuroQoL five-dimension self-report questionnaire (EQ-5D-3L), and readmission events 2 years after initiating the intervention. Data were collected at 4 instances (baseline, 1 month, 3 months, and 6 months after initiating the intervention), and analyzed with generalized estimating equations (GEEs).

Results

A total of 231 patients were recruited and allocated into an intervention (n=115) or control (n=116) group. The mean age of participants was 73.08 (SD 11.71) years. Most participants were diagnosed with paroxysmal AF (171/231, 74%), and the most frequent comorbidity was hypertension (162/231, 70.1%). Compared with the control group, the intervention group showed significantly greater improvement in approach coping strategies, medication adherence, and HRQoL at 1, 3, and 6 months (all P<.05). In addition, the intervention group showed significantly fewer readmission events within 2 years (OR 0.406, P=.03), compared with the control group.

Conclusions

The web-based integrated management program can significantly improve patients' coping strategy and medication adherence. Therefore, it can empower patients to maintain disease stability, which is a major factor in improving their HRQoL and reducing readmission events within 2 years.

Trial Registration

ClinicalTrials.gov NCT04813094; https://clinicaltrials.gov/ct2/show/NCT04813094.
The politics of civil society forms
Authors: Djindan Muhammad
Published: July 2021

Regardless of the debate on how and to what extent civil society contributes to enhance democratic practices, it is generally agreed that there is a reasonable link between civil society and democracy under certain conditions. The aim of this paper is to explore the politics of civil society forms and their contribution to maintain democratic practices in Jakarta. Building from the neo-Tocquevillean understanding of civil society, this article particularly analyses urban environmental activists’ strategy to adopt voluntary association and environmental spin off campaign as the forms of civic engagement to improve public policy in the province. Despite the lack of acknowledgement, this paper argues for the necessary inclusion and elaboration of spin off campaign and voluntary association in the Indonesian civil society literature because of their ability to facilitate diagonal accountability mechanism. Further analysis found that, however, the forms adopted by urban environmental activists suffer similar horizontal and vertical accountability problems frequently found in the more established civil society form (e.g. non-government organization). Nonetheless, the discussion in the paper provides an illustration about civil society’s ingenuity in pushing for democratic practices amidst the “democratic recession” in Indonesia.
Metaphoric Conceptualization of Social Reality in the Language of News Media
Authors: Karapetjana Indra , Roziņa Gunta
Published: July 2021

Today, social reality can hardly be viewed as the one-state-one-nationone language ideological framework (Bauman and Briggs, 2003). The modern multilingual and multicultural communities are inclined to examine social reality in a multiple variety of socio-economic and political manifestations and forms. To understand how social reality can be explored through examining certain socio-political processes in a country, the present paper aims at analysing the role of conceptual metaphor in cases when political scandals, involving corruption charges of high-ranking officials in Latvia are considered. For this purpose, the present study has focused on the analysis of selected commentaries that deal with corruption charges which were revealed in December 2019 issues of the magazine IR. The Latvian-origin weekly magazine IR was selected deliberately because; on the one hand, it has an enormous influence on how social reality is constructed and perceived by Latvian citizens. On the other hand, it was important to reveal that the evidence-based theoretical premises on the relationship between metaphor and society in the English language are applicable and work cross-linguistically in Latvian. The research presents a case study type. With the focus on the conceptualization of corruption-related social problems, selected discursive practices that dealt with the corruption cases being revealed by the news medium IR were considered. The results demonstrated that the journalists of the commentaries tend to take a critical discourse perspective on the representation of corruption-related issues and political events, which can be represented at the levels of abstraction. Conceptual metaphors contributed to mental representations of political issues and communication of social reality by conveying additional negative evaluation of such an inherently derogatory concept as corruption. The metaphors CORRUPTION IS DIRT, CORRUPTION IS GARBAGE, CORRUPTION IS NUCLEAR DISASTER, CORRUPTION IS A DISEASE also fulfil a cognitive function, helping to understand the concept of corruption in terms of another more concrete concept. The use of metaphors in the commentaries may have causal effects such as bringing about changes in the readers’ knowledge, beliefs and attitudes.
Hierarquias de gênero em questão (Gender hierarchies in question)
Authors: Birman Joel
Published: July 2021

A intenção deste artigo é o de destacar o campo social e existencial, hierarquia entre os gêneros numa perspectiva genealógica e tomando assim a construção histórica da categoria da mulher como mãe e a sua desconstrução posterior com o Primeiro Movimento Feminista.
Um pensamento diferencial ou fracional do poder: Laruelle, o princípio do poder e mais além (Differential or fractional thinking of power: Laruelle, the power principle and beyond)
Authors: Bruno Mario
Published: July 2021

O princípio do poder e o além deste princípio. As generalidades gregárias do poder (o Estado, a Luta de Classes, o Contrato, a Vontade geral etc.). O retorno ao materialismo político. O conceito de Continente político. O objeto pequeno (r). Os três “além” de Laruelle. A política fracional ou diferencial, o ser-político do sujeito e o Gozo além do princípio do poder.
The enigma of persistent hypertriglyceridemia: A Case Report
Authors: Dhaliwal Armaan , Ravi Soumiya , Bains Kanwal Naveen , Potharaju Anil , Shah Tasneem
Published: July 2021

A patient with a history of Mandibular hypoplasia, Deafness, Progeroid
Features Associated Lipodystrophy Syndrome (MDPL), a familial
lipodystrophy presented with hypertriglyceridemia induced pancreatitis
with triglycerides in the 3000s. This lipodystrophy occurs due to a
mutation in the POLD1 gene (DNA polymerase delta 1).
Inflammatory Myofibroblastic Tumor of the Larynx: Case Report
Authors: Foster Henry , Ow Thomas , Bottalico Danielle , Gorthey Scott , Ustun Berrin , Shifteh Keivan
Published: July 2021

Inflammatory Myofibroblastic Tumor is usually a benign tumor of
mesenchymal origin that is rarely found in the larynx. This case
explores the unique laryngeal location and presentation of this tumor as
well as the challenging radiographic and histologic findings.