bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-Care is Soul Care
Authors: Poppa Kristen
Published: October 2018

At the heart of soul care is self-care. Being able to love God and love others is rooted in how we love ourselves. Each person’s understanding of self-care is informed by their personal belief system and their implementation practices. This article will provide a multi-phasic model that describes the self-care journey and focuses on how to implement self-care practices. A key distinction of this model is that it is used in an ongoing fashion. To avoid confusion between beliefs and practice, attention will be given to the decision-making process for self-care implementation. Specific activities that address the physical, mental, emotional, spiritual, and relational parts of people will be discussed. The article will also consider the nuances of assessing self-care and why it is important to value self-care, which is in keeping with the greatest commandments provided by Jesus in Mark 12:28–30.
No Effect of Variations in Overstory Diversity and Phylogenetic Distance on Early Performance of Enrichment Planted Seedlings in Restoration Plantations
Authors: Schweizer Daniella , Brancalion Pedro H. S.
Published: October 2018

Enrichment planting is a strategy to increase tree diversity and reintroduce desirable species in restored forests, mainly in fragmented landscapes. However, the conditions that improve the performance of enrichment planted seedlings are not yet fully known. Here, we evaluate the role that overstory taxonomic diversity and mean overstory to seedling phylogenetic distance have as predictors of early performance of native tree seedlings planted beneath mixed-species restoration plantations in the Brazilian Atlantic Forest. By applying a phylogenetic approach, our study responds to recent calls for testing the application of such tools in restoration. We planted 12 mid- to late-successional species beneath a mixed-species restoration plantation with three nested tree diversity levels of 19, 58, and 107 species and estimated the mean phylogenetic distance between each seedling species and the overstory community. Seedling performance was not significantly affected by overstory diversity or mean phylogenetic distance. Overall good performance of the seedlings shows that enrichment planting beneath a mixed-species overstory can be successful even under variations in overstory species number and phylogenetic distance. However, significant species-specific differences in performance highlight the importance of an informed selection of which species to enrich plant.
Long-term mortality is increased in patients with undetected prediabetes and type-2 diabetes hospitalized for worsening heart failure and reduced ejection fraction
Authors: Pavlović Andrija , Polovina Marija , Ristić Arsen , Seferović Jelena P , Veljić Ivana , Simeunović Dejan , Milinković Ivan , Krljanac Gordana , Ašanin Milika , Oštrić-Pavlović Irena , Seferović Petar M
Published: October 2018

Background

We assessed the prevalence of newly diagnosed prediabetes and type-2 diabetes mellitus (T2DM), and their impact on long-term mortality in patients hospitalized for worsening heart failure with reduced ejection fraction (HFrEF).

Methods

We included patients hospitalized with HFrEF and New York Heart Association (NYHA) functional class II–III. Baseline two-hour oral glucose tolerance test was used to classify patients as normoglycaemic or having newly diagnosed prediabetes or T2DM. Outcomes included post-discharge all-cause and cardiovascular mortality during the median follow-up of 2.1 years.

Results

At baseline, out of 150 patients (mean-age 57 ± 12 years; 88% male), prediabetes was diagnosed in 65 (43%) patients, and T2DM in 29 (19%) patients. These patients were older and more often with NYHA class III symptoms, but distribution of comorbidities was similar to normoglycaemic patients. Taking normoglycaemic patients as a reference, adjusted risk of all-cause mortality was significantly increased both in patients with prediabetes (hazard ratio, 2.6; 95% confidence interval (CI), 1.1–6.3; p = 0.040) and in patients with T2DM (hazard ratio, 5.3; 95% CI, 1.7–15.3; p = 0.023). Likewise, both prediabetes (hazard ratio, 2.9; 95% CI, 1.1–7.9; p = 0.041) and T2DM (hazard ratio, 9.7; 95% CI 2.9–36.7; p = 0.018) independently increased the risk of cardiovascular mortality compared with normoglycaemic individuals. There was no interaction between either prediabetes or T2DM and heart failure aetiology or gender on study outcomes (all interaction p-values > 0.05).

Conclusions

Newly diagnosed prediabetes and T2DM are highly prevalent in patients hospitalized for worsening HFrEF and NYHA functional class II–III. Importantly, they impose independently increased long-term risk of higher all-cause and cardiovascular mortality.
Role competency scale on shared decision-making nurses: Development and psychometric properties
Authors: Tariman Joseph D , Katz Pamela , Bishop-Royse Jessica , Hartle Lisa , Szubski Katharine L , Enecio Toreend , Garcia Ima , Spawn Nadia , Masterton Katherine Jones
Published: October 2018

Objectives:

This study aimed to develop a scale that can measure the role competency of oncology nurses during shared decision-making process.

Methods:

A total of 226 oncology nurses who actively provide direct care to patients from inpatient and outpatient oncology units in the Midwest and Pacific Northwest completed the online or mail survey. Exploratory factor analysis and parallel analysis showed the multidimensionality of the role competency scale on shared decision-making nurses.

Results:

The role competency scale on shared decision-making nurses revealed four dimensions: knowledge, attitudes, communication, and adaptability. The 22 items have excellent internal consistency with a Cronbach’s alpha of 0.91. The four subscales also have adequate reliability with Cronbach’s alpha >0.70 as well as greater than 0.70 Spearman–Brown’s correlation coefficients in split-half reliability testing for each subscale.

Conclusion:

The new scale has the potential to be used as a clinical tool to assess the need for shared decision-making education and training in oncology nurses.
Investigating the Impact of System Quality on Service-Oriented Business Intelligence Architecture
Authors: Chan Lee-Kwun , Lau Phooi-Yee
Published: October 2018

Despite the recognized value that Business Intelligence (BI) systems bring to organizations, our understanding of the system quality and its impact on service-oriented architecture is limited. This study seeks to examine the impact of system quality on service-oriented BI architecture. Following the theory in the Information System success model, this study assesses the factors that can create impact to the individual and the organization. A total of 60 sample data were collected and analyzed using the partial least squares method. Majority of the respondents are the IT practitioners who hold managerial positions in their respective companies. The results suggest there are two sets of system quality factors. This study contributes to the literature of BI architecture. The managerial findings will be useful for BI stakeholders in the planning, reviewing, and implementing of SOA-based BI architecture.
Visualizing Bring-backs
Authors: Lizardo Omar , Stoltz Dustin S. , Taylor Marshall A. , Wood Michael Lee
Published: October 2018

The figure plots the number of articles that have attempted to “bring” something “back in” in the social sciences by publication year and number of citations. Andrew Abbott, taking a (pessimistic) sociology of knowledge perspective, identified this tendency—beginning with Homans’s classic article “Bringing Men Back in”—as emblematic of the tendency to rediscover old ideas in sociology. The plot shows that “bring-backs” did not become a common yearly occurrence until the mid to late 1990s but are now relatively frequent. The most successful bring-backs have been relatively abstract things such as the “state” and “society” and more recently, “culture,” “knowledge,” and “values.”
Infectious Endophthalmitis: Trends in Microbiology, Management, and Surgical Techniques
Authors: Keffer Stephen T. , Chin Eric K. , Almeida David R.P.
Published: October 2018

Purpose:

The purpose of this review is to provide an update on etiologies, preventive practices, management options, and surgical techniques for infectious endophthalmitis.

Methods:

A literature search was conducted for studies published over the past 5 years.

Results:

Endophthalmitis continues to be an uncommon but dangerous complication following cataract surgery. Recently, intravitreal injections have become heavily utilized as a treatment for various ocular diseases, leading to a greater incidence of postinjection infections. Likewise, long-term risk of endophthalmitis should always be a consideration following glaucoma surgery and implanted drainage devices. Although significant overlap exists for causative organisms among the different etiologies, more targeted studies are needed to better optimize treatment. There has been a lack of updates to treatment guidelines since the Endophthalmitis Vitrectomy Study was published in 1995. Despite promising outcomes seen with newer surgical techniques, the lack of randomized clinical trials represents a major barrier to widespread implementation of these approaches.

Conclusions:

Povidone-iodine prophylaxis remains the primary evidence-based technique for decreasing the rates of endophthalmitis following intraocular procedures. Intracameral antibiotics have gained momentum in recent years and represent a step forward in mitigating the risk of infection with cataract surgery, although some debate still exists. Newer surgical techniques for vitrectomy that improve visualization, minimize surgical trauma, and decrease operative time would benefit from large-scale randomized trials.
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA
Authors: Konstandin Nikola P. , Pastore Friederike , Herold Tobias , Dufour Annika , Rothenberg-Thurley Maja , Hinrichsen Tanja , Ksienzyk Bianka , Tschuri Sebastian , Schneider Stephanie , Hoster Eva , Berdel Wolfgang E. , Woermann Bernhard J. , Sauerland Maria C. , Braess Jan , Bohlander Stefan K. , Klein Hanns-Georg , Hiddemann Wolfgang , Metzeler Klaus H. , Spiekermann Karsten
Published: October 2018

Biallelic mutations of the CCAAT/enhancer binding protein α (CEBPA) gene define a distinct genetic entity of acute myeloid leukemia (AML) with favorable prognosis. The presence of GATA2 and CSF3R mutations that are specifically associated with this subgroup but not mutated in all samples suggests a genetic heterogeneity of biCEBPA-mutated AML. We characterized the mutational landscape of CEBPA-mutated cytogenetically normal AML by targeted amplicon resequencing. We analyzed 48 biallelically mutated CEBPA (biCEBPA), 32 monoallelically mutated CEBPA (moCEBPA), and 287 wild-type CEBPA (wtCEBPA) patient samples from German AML Cooperative Group studies or registry. Targeted sequencing of 42 genes revealed that moCEBPA patients had significantly more additional mutations and additional mutated genes than biCEBPA patients. Within the group of biCEBPA patients, we identified 2 genetic subgroups defined by the presence or absence of mutations in chromatin/DNA modifiers (C), cohesin complex (C), and splicing (S) genes: biCEBPACCSpos (25/48 [52%]) and biCEBPACCSneg (23/48 [48%]). Equivalent subgroups were identified in 51 biCEBPA patients from the Cancer Genome Project. Patients in the biCEBPACCSpos group were significantly older and had poorer overall survival and lower complete remission rates following intensive chemotherapy regimens compared with patients in the biCEBPACCSneg group. Patients with available remission samples from the biCEBPACCSpos group cleared the biCEBPA mutations, but most had persisting CCS mutations in complete remission, suggesting the presence of a preleukemic clone. In conclusion, CCS mutations define a distinct biological subgroup of biCEBPA AML that might refine prognostic classification of AML. This trial was registered at www.clinicaltrials.gov as #NCT00266136 and NCT01382147.
COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging
Authors: Washko George R. , Parraga Grace
Published: October 2018

A number of chronic diseases have benefited from both imaging and personalised medicine, but unfortunately, for patients with chronic obstructive pulmonary disease (COPD), there has been little clinical uptake or recognition of the key advances in thoracic imaging that might help detect disease early, or, perhaps more importantly, might help develop and phenotype patients for novel or personalised therapies that may halt disease progression. We outline our vision for how computed tomography and magnetic resonance imaging may be used to better inform COPD patient care, and, perhaps more importantly, how these may be used to help develop new therapies directed at early disease. We think that imaging and precision medicine should be considered and used together as “precision imaging” at specific stages of COPD when the major pathologies may be more responsive to therapy. While “precision medicine” is the tailoring of medical treatment to individual patients, we define “precision imaging” as the tailoring of specific therapies and interventions to individual patients with a detailed quantitative understanding of their specific imaging phenotypes and measurements. Finally, we stress the importance of “seeing” the pathology, because without this understanding, you can neither treat nor cure patients with COPD.
Natural History of Obesity Subphenotypes: Dynamic Changes Over Two Decades and Prognosis in the Framingham Heart Study
Authors: Echouffo-Tcheugui Justin B , Short Meghan I , Xanthakis Vanessa , Field Patrick , Sponholtz Todd R , Larson Martin G , Vasan Ramachandran S
Published: October 2018

Context

The natural histories of obesity subphenotypes are incompletely delineated.

Objectives

To investigate dynamic changes in obesity subphenotypes and associations with outcomes.

Design, Setting, Participants, and Measurements

Framingham Offspring Cohort participants (n = 4291) who attended the examination cycles 2 (1979 to 1983) to 7 (1998 to 2001), which included 26,508 participant observations. Obesity subphenotypes [metabolically healthy nonobese (MHNO), metabolically healthy obese (MHO), metabolically unhealthy nonobese (MUNO), and metabolically unhealthy obese (MUO)] were ascertained based on metabolic health (<2 Adult Treatment Panel III criteria). The outcomes were subclinical cardiovascular disease (CVD), incident diseases [diabetes, hypertension, chronic kidney disease (CKD), CVD], and all-cause mortality.

Results

At baseline, 4% and 31% of participants exhibited the MHO and MUNO subphenotypes, respectively. Four-year probability of MHO participants becoming MUO was 43% in women and 46% in men. Compared with MHNO, MHO participants had 1.28-fold (95% CI, 0.85 to 1.93) and 1.92-fold (95% CI, 1.38 to 2.68) higher odds of subclinical CVD and coronary artery calcification, respectively; corresponding values for MUNO were 1.95 (1.54 to 2.47) and 1.92 (1.38 to 2.68). During follow-up (median of 14 years), 231 participants developed diabetes, 784 hypertension, 423 CKD, 639 CVD, and 1296 died. Compared with MHNO, MHO conferred higher risks of diabetes [hazard ratio (HR), 4.69; 95% CI, 2.21 to 9.96] and hypertension (HR, 2.21; 95% CI, 1.66 to 2.94). Compared with MUO, MHO conferred lower risks of diabetes (0.21; 0.12 to 0.39), CVD (0.64; 0.43 to 0.95), and CKD (0.44; 0.27 to 0.73), but similar hypertension, cardiovascular mortality, and overall mortality risks.

Conclusion

Over time, most MHO participants developed metabolic abnormalities and clinical disease. The MHO subphenotype is a harbinger of future risk.
Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth
Authors: Saturnino Alicia Pérez , Lust Katharina , Wittbrodt Joachim
Published: October 2018

Patterning of a continuously growing naive field in the context of a life-long growing organ such as the teleost eye is of highest functional relevance. Intrinsic and extrinsic signals were proposed to regulate lineage specification in progenitors that exit the stem cell niche in the ciliary marginal zone (CMZ). The proper cell type composition arising from those progenitors is prerequisite for retinal function. Our findings in the teleost medaka (Oryzias latipes) uncover that the Notch–Atoh7 axis continuously patterns the CMZ. The complement of cell-types originating from the two juxtaposed progenitors marked by Notch or Atoh7 activity contains all constituents of a retinal column. Modulation of Notch signalling specifically in Atoh7-expressing cells demonstrates the crucial role of this axis in generating the correct cell type proportions. After transiently blocking Notch signalling, retinal patterning and differentiation is reinitiated de novo. Taken together we show that Notch activity in the CMZ continuously structures the growing retina by juxtaposing Notch and Atoh7 progenitors giving rise to distinct, complementary lineages, revealing a coupling of de novo patterning and cell-type specification in the respective lineages.
CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments
Authors: Boel Annekatrien , De Saffel Hanna , Steyaert Wouter , Callewaert Bert , De Paepe Anne , Coucke Paul J. , Willaert Andy
Published: October 2018

Targeted genome editing by CRISPR/Cas9 is extremely well fitted to generate gene disruptions, although precise sequence replacement by CRISPR/Cas9-mediated homology-directed repair (HDR) suffers from low efficiency, impeding its use for high-throughput knock-in disease modeling. In this study, we used next-generation sequencing (NGS) analysis to determine the efficiency and reliability of CRISPR/Cas9-mediated HDR using several types of single-stranded oligodeoxynucleotide (ssODN) repair templates for the introduction of disease-relevant point mutations in the zebrafish genome. Our results suggest that HDR rates are strongly determined by repair-template composition, with the most influential factor being homology-arm length. However, we found that repair using ssODNs does not only lead to precise sequence replacement but also induces integration of repair-template fragments at the Cas9 cut site. We observed that error-free repair occurs at a relatively constant rate of 1-4% when using different repair templates, which was sufficient for transmission of point mutations to the F1 generation. On the other hand, erroneous repair mainly accounts for the variability in repair rate between the different repair templates. To further improve error-free HDR rates, elucidating the mechanism behind this erroneous repair is essential. We show that the error-prone nature of ssODN-mediated repair, believed to act via synthesis-dependent strand annealing (SDSA), is most likely due to DNA synthesis errors. In conclusion, caution is warranted when using ssODNs for the generation of knock-in models or for therapeutic applications. We recommend the application of in-depth NGS analysis to examine both the efficiency and error-free nature of HDR events.

This article has an associated First Person interview with the first author of the paper.
Tropomyosin 3.5 protects the F-actin networks required for tissue biomechanical properties
Authors: Cheng Catherine , Nowak Roberta B. , Amadeo Michael B. , Biswas Sondip K. , Lo Woo-Kuen , Fowler Velia M.
Published: October 2018

Tropomyosins (Tpms) stabilize F-actin and regulate interactions with other actin-binding proteins. The eye lens changes shape in order to focus light to transmit a clear image, and thus lens organ function is tied to its biomechanical properties, presenting an opportunity to study Tpm functions in tissue mechanics. Mouse lenses contain Tpm3.5 (also known as TM5NM5), a previously unstudied isoform encoded by Tpm3, which is associated with F-actin on lens fiber cell membranes. Decreased levels of Tpm3.5 lead to softer and less mechanically resilient lenses that are unable to resume their original shape after compression. While cell organization and morphology appear unaffected, Tmod1 dissociates from the membrane in Tpm3.5-deficient lens fiber cells resulting in reorganization of the spectrin–F-actin and α-actinin–F-actin networks at the membrane. These rearranged F-actin networks appear to be less able to support mechanical load and resilience, leading to an overall change in tissue mechanical properties. This is the first in vivo evidence that a Tpm protein is essential for cell biomechanical stability in a load-bearing non-muscle tissue, and indicates that Tpm3.5 protects mechanically stable, load-bearing F-actin in vivo.

This article has an associated First Person interview with the first author of the paper.
Superior low-speed control of a permanent magnet synchronous motor with digital encoder
Authors: Wang M-S , Kung Y-S , Thi H , Chang C-M
Published: October 2018

Low-speed control is indispensable to several servo applications. Generally, motor speed acquired from the so-called M method is averaged by counting the number of pulses from the encoder at a fixed time period. As a result, a long detection delay, due to speeds lower than the minimum measurable value determined by the sampling frequency and the resolution of the encoder, may degrade the performance or even make systems unstable. In this paper, instead of using disturbance torque observers, a reference model derived from a full-order observer to denote the permanent magnet synchronous motor (PMSM) model is employed to approach instantaneous speed and improve the low-speed control performance. Two structures of model reference control are proposed. A proportional—integral—differential (PID) controller is located on the feedback path for one structure and on the forward path for the other. Additionally, in the latter structure, a composite signal obtained by adding motor speed and the estimated speed timed respective weighting factors is fed back to the input terminal to compare the speed command. This will further improve the performance. A digital signal processor-based drive provides experimental results, which show the improved speed resolution from 7.5 r/min to 1 r/min and the effectiveness of the system with loading.
Promoting Exercise Adherence Through Groups: A Self-Categorization Theory Perspective
Authors: Beauchamp Mark R.
Published: October 2018

The hypothesis presented in this paper is that adherence to exercise programs can be understood, and fostered through intervention, by considering how social identities form within group settings. This paper explains these processes from a self-categorization theory perspective.
Development of a hyperspectral imaging technique with internal scene scan for analysing the chemistry of food
degradation
Authors: Chen Guo , Huang Jung
Published: October 2018

Hyperspectral imaging (HSI) can provide valuable information about the spatial distribution of ingredients in an
object, therefore the technique has been widely adopted in numerous applications, ranging from remote sensing and land
planning, food quality control, to biomedical applications. However, HSI instruments are expensive, which has limited the
technique to some high-end applications. In this study, we developed a cost-effective HSI technique with an internal
scene-scan mechanism, which enables rapid acquisitions of a scene without moving the instrument or the tested object.
The apparatus was characterised, revealing an imaging resolution of 0.4 mm in a field of view (FoV) of 10 cm and a
spectral resolution of 1.3 nm in the 40–800 nm visible light region. We succeeded in applying our apparatus to analyse the
oxidation processes of apple and meat, which demonstrated our design and relevant data analysis to be of high value to
visualise chemistry related to food quality and safety.
Could differences in implicit attitudes to sexual concurrency play a role in generalized HIV epidemics?
Authors: Kenyon Chris R. , Wolfs Kenny , Osbak Kara , Malataliana Maleeto , Van Hal Guido , Zondo Sizwe , van Lankveld Jacques
Published: October 2018

Background: Sexual partner concurrency has been implicated in the genesis of generalized HIV epidemic in South Africa. Most South Africans, however, disapprove of concurrency in surveys. These surveys test individuals’ explicit attitudes which are susceptible to a number of important biases such as the social desirability bias. Assessment of implicit cognitions have been found to be better predictors of behaviour in socially sensitive domains. We hypothesized that South Africans may have implicit attitudes more tolerant of concurrency than lower concurrency prevalence populations.

Methods: To test this hypothesis, we developed a concurrency-implicit association test (C-IAT) and compared the C-IATs of samples of South African and Belgian university students.

Results: We found a large and statistically significant difference in the C-IAT between the South Africans (D600-score = -0.009, indicating absence of preference for concurrency or monogamy) and Belgians (D600-score = 0.783, indicating a strong preference for monogamy; t-test = 13.3; P < 0.0001). The effect size measure, Cohen’s d, was found to be 0.88, which is considered a large effect size in this field.

Conclusions: Our results are compatible with the thesis that differences in implicit attitudes to concurrency play a role in the genesis of generalised HIV epidemics.
Synthesis of Equations For Ruled Surfaces With Two Curvilinear And One Rectangular Directrixes
Authors: Кокарева Я. , Kokareva Ya.
Published: October 2018

Ruled surfaces have long been known and are widely used in construction, architecture, design and engineering. And if from the technical point of view the developable surfaces are more attractive, then architecture and design successfully experiment with non-developable ones. In this paper are considered non-developable ruled surfaces with three generators, two of which are curvilinear ones. According to classification, such surfaces are called twice oblique cylindroids. In this paper has been proposed an approach for obtaining of twice oblique cylindroids by immersing a curve in a line congruence of hyperbolic type. Real directrixes of such congruence are a straight line and a curve. It has been proposed to use helical lines (cylindrical and conical ones) as a curvilinear directrix, and a helical line’s axis as the straight one. Then the congruence’s rectilinear ray will simultaneously intersect the helical line and its axis. Congruence parameters are the line’s pitch and the guide cylinder or cone’s radius. The choice of the curvilinear directrix is justified by the fact that the helical lines have found a wide application in engineering and architecture. Accordingly, the helical lines based surfaces can have a great potential. In this paper have been presented parametric equations of the considered congruences. The congruence equations have been considered from the point of view related to introducing a new curvilinear coordinate system. The obtained system’s coordinate surfaces and coordinate lines have been also studied in the paper. To extract the surface, it is necessary to immerse the curve in the congruence. To synthesize the equations has been used a constructive-parametric method based on the substitution of the immersed line’s parametric equations in the congruence equations according to a special algorithm. In the paper have been presented 5 examples for the synthesis of ruled surfaces equations such as the twice oblique cylindroid and their visualization. The method is universal and algorithmic, and therefore easily adaptable for the automated construction of surfaces with variable parameters of both the congruence and the immersed line.
SMASH! The Salford medication safety dashboard
Authors: Williams Richard , Keers Richard , Gude Wouter T. , Jeffries Mark , Davies Colin , Brown Benjamin , Kontopantelis Evangelos , Avery Anthony J. , Ashcroft Darren M. , Peek Niels
Published: October 2018

Background

Patient safety is vital to well-functioning health systems. A key component is safe prescribing, particularly in primary care where most medications are prescribed. Previous research has demonstrated that the number of patients exposed to potentially hazardous prescribing can be reduced by interrogating the electronic health record (EHR) database of general practices and providing feedback to general practitioners (GPs) in a pharmacist-led intervention. We aimed to develop and roll out an online dashboard application that delivers this audit and feedback intervention in a continuous fashion.

Method

Based on initial system requirements, we designed the dashboard’s user interface over three iterations with six GPs, seven pharmacists and a member of the public. Prescribing safety indicators from previous work were implemented in the dashboard. Pharmacists were trained to use the intervention and deliver it to general practices.

Results

A web-based electronic dashboard was developed and linked to shared care records in Salford, UK. The completed dashboard was deployed in all but one (n = 43) general practices in the region. By November 2017, 36 pharmacists had been trained in delivering the intervention to practices. There were 135 registered users of the dashboard, with an average of 91 user sessions a week.

Conclusion

We have developed and successfully rolled out of a complex, pharmacist-led dashboard intervention in Salford, UK. System usage statistics indicate broad and sustained uptake of the intervention. The use of systems that provide regularly updated audit information may be an important contributor towards medication safety in primary care.
DOUBLE SIZE FULLJET FIELD RAINFALL SIMULATOR FOR COMPLEX INTERRILL AND RILL EROSION STUDIES
Authors: Kavka Petr , Strouhal Luděk , Jáchymová Barbora , Krása Josef , Báčová Markéta , Laburda Tomáš , Dostál Tomáš , Devátý Jan , Bauer Miroslav
Published: October 2018

Field observations and consecutive modelling of soil erosion events proved to be essential for understanding and predicting erosion and sediment transport. An experimental approach often utilizes a large variety of rainfall simulators. In this technical note a complex methodology is introduced, using a mobile rainfall simulator developed at the Czech Technical University in Prague. An experimental setup with two watered plots (16 + 1 m2) was established, which enables simultaneous measurements in two scales and monitoring of surface runoff, flow velocity, infiltration, sediment subsurface flow, vegetation cover effect suspended solids and phosphorus transport, surface roughness and surface evolution under rainfall and other variables. The simulator is built on a trailer transportable by car with folding arm carrying four FullJet WSQ nozzles operating independently. The configuration and water pressure 0.7 bar leads to the total watered area 2.4 x 9.6 m. Average drop size (d50) reaches 1.75 mm for 0.7 bar pressure. Christiansen uniformity index CU reaches 85%. A selection of experimental results highlights both the advantages and the weaknesses of the presented experimental setup.
Shakespearean Ballads in Thomas Percy’s Reliques of Ancient English Poetry: Transition from Oral Songs to Printed Historical Documents
Authors: Mihara Minoru
Published: October 2018

Thomas Percy’s ballad collection, Reliques of Ancient English Poetry, marks a point of intersection between balladry and Shakespeareana, which both went through a transitional phase from vocal performance to literary undertaking in the eighteenth century. In the Reliques, ballads that had been orally transmitted by minstrels were changed into validated printed sources for a scholarly project. This transition helped eighteenth-century editors gain a historical understanding of Shakespeare and emend his traditionally received texts. These editors were persuaded to use the ballads in the Reliques as reliable sources for their emendation since they were printed as authoritative documents that were useful for their academic editions of Shakespeare. They gained easy textual access to the printed ballads in the Reliques to search for contextual or emendatory materials. A comparison of four Shakespeare-related ballads in the Reliques (“King Cophetua and the Beggar-Maid,” “Take Thy Old Cloak about Thee,” “Willow, Willow, Willow,” and “The Passionate Shepherd to His Love”) to their counterparts in editions of Shakespeare reveals that the ballads that were printed as historical documents in the Reliques advanced the editors’ contextual illustration of Shakespeare and that they authorized the emendation of the textus receptus. This article focuses on the effect of the historical information provided by Percy’s printed ballads on George Steevens’s and Edmond Malone’s contextualization of Shakespeare and on their emendation of Shakespearean texts. In addition, it concentrates on the possibility that Edward Capell referred to Shakespearean ballads in Percy’s Reliques combined with old Quarto editions of Shakespeare’s works.
Philological Complement to Motets from the Chansonnier de Noailles (BnF f. fr. 12615), Part 1: Language of the Scribe and Versification
Authors: Rosenberg Samuel N. , Doss-Quinby Eglal
Published: October 2018

This text examines philological issues not covered in Motets from the Chansonnier de Noailles, music edited and introduced by Gaël Saint-Cricq, texts edited and translated by Eglal Doss-Quinby and Samuel N. Rosenberg (A-R Editions, 2017); it focuses on the hybrid dialect of the scribe and the varied modalities of the works’ versification.
Aspekty prawne kontaktów z dzieckiem
Authors: Zajączkowska Joanna
Published: October 2018

Artykuł przedstawia analizę instytucji kontaktów z dzieckiem, będącą stosunkowo nową regulacją w prawie rodzinnym. Rozważania teoretycznoprawne mają na celu określenie charakteru prawnego kontaktów i wskazać, że mają one charakter rodzinnoprawny i osobisty. Analizie poddano również obustronne prawo i obowiązek kontaktu z uwzględnieniem roszczenia po stronie dziecka, jak również samo pojęcie kontaktu, szczególnie w odniesieniu do równolegle występującego pojęcia osobistej styczności. Przy okazji omówiono bowiem instytucję osobistej styczności występującą przy przysposobieniu. W artykule przedstawiona została koncepcja konieczności ustalenia obowiązku do nienaruszania kontaktu przez jedno z rodziców zamieszkujące z dzieckiem, a także przemawiająca za wprowadzeniem instytucji zawieszenia kontaktów. W odniesieniu do jednego z rodziców sprawującego władzę rodzicielską przyjęto, że kontakt przyjmuje postać uśpionego roszczenia, które aktualizuje się w momencie rozpadu rodziny. W efekcie poczynione wnioski mają na celu wskazanie wykładni przepisów art. 113–1136 k.r.o., a także art. 1191 k.r.o., co sprawia, że rozważania mają również znaczenie praktyczne dla utrzymywania kontaktów z dzieckiem.
Mobilność jako potencjalność: sposoby rozumienia mobilności z perspektywy nowych technologii i paradygmatu mobilności
Authors: Rogowski Łukasz
Published: October 2018

Artykuł odnosi się do paradygmatu nowych mobilności (new mobilities paradigm) jako perspektywy opisu współczesnych zjawisk społecznych związanych z mobilnością i przemieszczaniem się. Wskazuje na zależność pomiędzy nowymi formami działań aktorów społecznych a rozwojem technologicznym. Opisuje trzy wymiary relacji technologia – mobilność – znaczenia społeczne: rozumienie przestrzeni, rozumienie czasu oraz tożsamość i podmiotowość jednostek. Najważniejszym założeniem artykułu jest jednak to, że mobilność jest definiowana społecznie. Na podstawie wyników jakościowych badań empirycznych wskazano kilka sposobów społecznego rozumienia mobilności: możliwość przenoszenia, dostępność, łączność z Internetem, porównanie z analogowością/stacjonarnością. W rezultacie mobilność pokazano nie jako stałą cechę społeczną, ale jako potencjalność.
Przejrzystość finansów publicznych a kształtowanie aktywnych postaw obywatelskich
Authors: Salachna Joanna M. , Tyniewicki Marcin
Published: October 2018

Celem niniejszego artykułu jest analiza oddziaływania zasady przejrzystości finansów publicznych, tj. rzetelnego informowania o tych finansach, na kształtowanie i zmianę postaw obywatelskich. Wynika on z niezwykle istotnego, naszym zdaniem, problemu: w jaki sposób władza publiczna powinna informować o procesach gromadzenia i wydatkowania środków publicznych, mając na uwadze z jednej strony skomplikowaną materię finansów publicznych, z drugiej zaś – różnorodnych, pod względem wykształcenia, odbiorców tworzących ogół społeczeństwa? Autorzy stawiają hipotezę, że dotychczasowy sposób realizacji zasady przejrzystości finansów publicznych, a więc sposób przekazywania informacji o tych finansach jest niewłaściwy (niezrozumiały) z punktu widzenia społecznego (adresata). Obecnie w Polsce zasada ta jest głównie skoncentrowana na mniej lub bardziej profesjonalnym odbiorcy, choć jej aspekt społeczny jest dostrzegany przez doktrynę. Zdaniem autorów informowanie o sprawach finansowych państwa powinno odbywać się stosownie do wykształcenia adresatów, będących przecież mocodawcą władzy publicznej. Niniejsza publikacja jest częścią zainicjowanych przez autorów szerokich badań nad rolą wartości moralnych w dystrybucji środków publicznych przez rządzących. W artykule zostały wykorzystane niereaktywne (nieempiryczne) metody badawcze skupiające się na analizie literatury i regulacji prawnych obowiązujących w Polsce.
Teachers’ Beliefs and Practices of Task-Based Language Teaching in Chinese as a Second Language Classrooms
Authors: Zhang Yumei , Luo Shaoqian
Published: October 2018

Chinese as a second language (CSL) policy makers and scholars began to introduce task-based language teaching (TBLT) to CSL teaching more than a decade ago. However, policy innovations or theoretical precepts are not necessarily the blueprints of teachers’ classroom practice. It is assumed that teachers are more likely to accept or apply the new approach if the new philosophy is concordant with their existing beliefs. This study attempts to examine the prospect of TBLT application in CSL teaching by exploring the extent to which TBLT philosophy has found its way into CSL teachers’ beliefs. The research also probes into teachers’ practices to explore whether their beliefs in TBLT could be actualized. A questionnaire, classroom observations and interviews have been employed. The results indicate that the Chinese teachers have strong faith in the effectiveness of TBLT, but they doubt its feasibility. Their difficulties and confusion in realizing their beliefs in practice, in turn, lead to their faith in TBLT philosophy having a peripheral status in their belief system. This may imply the bi-directional causal relationships between teachers’ beliefs and practices. The factors revealed make clear the responsibilities or measures to be taken at social-cultural, institutional and internal levels. The findings generate empirical insights into implementations of pedagogical innovations.
Relationship Between Tactical Performance, Somatic Maturity and Functional Capabilities in Young Soccer Players
Authors: Borges Paulo Henrique , Cumming Sean , Ronque Enio R.V. , Cardoso Felippe , Avelar Ademar , Rechenchosky Leandro , Costa Israel Teoldo da , Rinaldi Wilson
Published: October 2018

The aim of the study was to investigate the relationship between tactical performance, somatic maturity, and functional capabilities in young soccer players. Study participants were 48 soccer players (14.80 ± 1.5 years) belonging to an extension project at the State University of Maringa - Brazil. Anthropometric measurements of body mass, body height, and sitting height were carried out. The number of years to peak height velocity (PHV) was used as an index of maturation. Evaluations of functional fitness included the following tests: sit-and-reach, Yo-Yo Intermittent Recovery Test Level 1, handgrip test, modified abdominal test, and vertical jumps (Counter Movement Jump and Jump Squat). Tactical performance was assessed through the System of Tactical Assessment in Soccer (FUT-SAT). Multiple Linear Regression models were used to estimate the relative contributions of functional and maturational capacities to tactical performance. The results indicated weak associations between the tactical performance indices and somatic maturity, functional capacity, and anthropometric attributes (r < 0.40). The Yo-Yo Test contributed to 36% of the defensive tactic performance variation in the under 13 category. These results suggest that the level of maturity, growth status, and functional fitness have limited impact on tactical performance of young soccer players.
Acceleration and Speed Performance of Brazilian Elite Soccer Players of Different Age-Categories
Authors: Loturco Irineu , Jeffreys Ian , Kobal Ronaldo , Cal Abad César C. , Ramirez-Campillo Rodrigo , Zanetti Vinicius , Pereira Lucas A. , Nakamura Fábio Y.
Published: October 2018

This study aimed to compare vertical jump ability (squat-jump [SJ] and countermovement-jump [CMJ]), relative to body mass mean propulsive power in the jump-squat (MPP-REL JS), and the 0-5, 5-10, and 10-20 m acceleration and speed among soccer players from the same professional club, divided into age-categories (U15 [n = 20], U17 [n = 53], U20 [n = 22] and senior [n = 25] players). The tests were performed at the start of the preseason in indoor facilities. The magnitude-based inference approach and the standardized differences (based on effect sizes) were used to compare the age-groups. The SJ, CMJ, and MPP-REL JS increased across the age-groups up to U20, the latter being similar to senior players. Interestingly, the 0-5 m acceleration was likely and possibly higher in U15 players compared to U17 and senior players. Although soccer athletes improve their unloaded and loaded jump abilities across the age-categories (plateauing during adulthood), the same does not hold true for acceleration capacity, from the early phases of players’ development (i.e., U15). Strength and conditioning professionals should seek effective strategies to minimize impairment in maximal acceleration performance of elite soccer players throughout their prospective training programs.
SHOX gene deletion screening by FISH in children with short stature and Madelung deformity and their characteristics
Authors: Kurnaz Erdal , Savaş-Erdeve Şenay , Çetinkaya Semra , Aycan Zehra
Published: October 2018

Background

The short stature homeobox-containing (SHOX) gene strongly affects height. Therefore, a better understanding ofSHOXhaploinsufficiency could be advantageous to early diagnosis and treatment. We investigated the rate ofSHOXhaploinsufficiency in patients of short stature and documented their anthropometric measurements.

Methods

Between 2010 and 2017, we evaluated 86 patients (70 females, 16 males; age 4.3–18 years) with clinical diagnoses of short stature and Madelung deformity (MD). Clinical abnormalities are presented for patients with MD with and withoutSHOXhaploinsufficiency as determined by fluorescencein situhybridisation (FISH).

Results

According to our inclusion criteria, 78 of 86 patients (70 females, 16 males) had short stature (height <−2.5 standard deviation [SD]) and a family history suggestive of short stature. Eight patients had short stature, a family history suggestive of short stature and MD. MD was obvious in eight children in radiographic examinations. Although five of these had no deletion ofSHOX, three had deletion of this gene. The deletion detection rate was 37.5% in the individuals with short stature and MD, i.e. Leri-Weill dyschondrosteosis syndrome (LWS), whilst no deletions were detected in the individuals with only short stature. One individual responded well to growth hormone (GH) treatment for the first 2 years but then developed an intolerance with persistently elevated insulin-like growth factor-1 (IGF-1) levels.

Conclusions

As we likely missed cases due to our methodology, the routine analysis forSHOXscreening should be firstly multiplex ligation-dependent probe amplification (MLPA). The incidence of MD may have been higher in the cohort if X-rays were performed in all individuals. GH treatment was not well tolerated in one case due to persistently elevated IGF-1 levels, and long-term evaluations of patients withSHOXdeficiency are required.
Antipassive constructions: Correlations of form and function across languages
Authors: Vigus Meagan
Published: October 2018

This paper presents a cross-linguistic investigation of the antipassive within the framework of Radical Construction Grammar. Based on function, this study identifies constructions in 70 languages from 25 language families and four geographical macro areas. Iconically motivated correlations were found between functions and the morphosyntactic strategies they employ. The results of this study suggest that constructions indicating the lower individuation of patients and constructions indicating the lower affectedness of patients, previously grouped together as ‘antipassive’, should be considered two separate construction types. This is based on their separate functions, the distinct morphosyntactic strategies used to encode them across languages, and differences in productivity with regard to semantic classes of verbs.
Comparatives in Melanesia: Concentric circles of convergence
Authors: Schapper Antoinette , de Vries Lourens
Published: October 2018

Using a sample of 116 languages, this article investigates the typology of comparative constructions and their distribution in Melanesia, one of the world’s least-understood linguistic areas. We present a rigorous definition of a comparative construction as a “comparative concept”, thereby excluding many constructions which have been considered functionally comparatives in Melanesia. Conjoined comparatives are shown to dominate at the core of the area on the island of New Guinea, while (monoclausal) exceed comparatives are found in the maritime regions around New Guinea. Outside of Melanesia adpositional and other comparative constructions including particle comparatives are most frequent in Austronesian languages. The unity of the conjoined comparative type in the core Melanesian area illustrates that, while morpho-syntactic profiles of Melanesian languages are heterogenous, significant convergence in the “ways of saying things” can be found across the region. Additionally, we find no cases of clause chaining constructions being used for encoding comparatives, even in canonical clause chaining languages of central New Guinea. Our findings thus offer no support for Stassen’s claim of a correlation between temporal chaining type and comparative construction type. Instead we suggest that an areal preference for mini-clauses may explain the dominance of the conjoined comparative in Melanesia.