bluuebunny/crossref_metadata_2025 huggingface dataset:
The Function of RAS Mutation in Cancer and Advances in its Drug Research
Authors: Chen Shijie , Li Fengyang , Xu Dan , Hou Kai , Fang Weirong , Li Yunman
Published: May 2019

RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has
long been a vital research target for cancer. Its function is to transform the extracellular environment into a cascade
of intracellular signal transduction. RAS mutant protein regulates tumor cell proliferation, apoptosis, metabolism
and angiogenesis through downstream MAPK, PI3K and other signaling pathways. In KRAS or other
RAS-driven cancers, current treatments include direct inhibitors and upstream/downstream signaling pathway
inhibitors. However, the research on these inhibitors has been largely restricted due to their escape inhibition and
off-target toxicity. In this paper, we started with the role of normal and mutant RAS genes in cancer, elucidated
the relevant RAS regulating pathways, and highlighted the important research advancements in RAS inhibitor
research. We concluded that for the crosstalk between RAS pathways, the effect of single regulation may be
limited, and the multi-target drug combined compensation mechanism is becoming a research hotspot.
Medicinal Importance of Azo and Hippuric Acid Derivatives
Authors: Tahir Tehreem , Ashfaq Muhammad , Asghar Humna , Shahzad Mirza I. , Tabassum Rukhsana , Ashfaq Areeba
Published: May 2019

In this review, specific therapeutic and medicinal advantages including antiviral, antibacterial, antifungal and antitumor, strategies for drug designing, structure-activity relationship, advances in the syntheses of azo and hippuric acid derivatives of more than 50 compounds have been discussed since 2009-2018. It is found that phenyl-diazenyl azo derivatives and pyridinyl substituted hippuric acid derivatives showed promising antiretroviral potential. The incorporation of azo functionality to the respective quinolones and coumarin moieties and the insertion of thiocarbazone to hippuric acid displayed immense antibacterial activities. While, azo and hippuric acid derivatives of triazole and phenyl species gave maximum fungicidal as well as cytotoxic activities.
Insulin Management for Type 1 Diabetic Patients During Social Alcohol Consumption: The SPRITZ Study
Authors: Cipponeri Elisa , Blini Cesare , Lamera Christian , De Mori Valentina , Veronesi Giovanni , Bossi Antonio Carlo
Published: May 2019

Background :

There is no data available on the best insulin treatment to counteract the effects
of glucose excursions due to a moderate alcohol intake associated with portions of slight fat and
protein-containing food, as often the case during social happenings or “happy hours”.
Introduction: This study analyzes the glycemic control and quality of life in 8 adult type 1 diabetic
(T1D) patients on insulin-pump therapy which were invited to consume a traditional Italian aperitif
(“Spritz” and chips).

Introduction :

This study analyzes the glycemic control and quality of life in 8 adult type 1 diabetic
(T1D) patients on insulin-pump therapy which were invited to consume a traditional Italian aperitif
(“Spritz” and chips).

Methods:

Patients consumed Spritz aperitif twice: using their habitual bolus, based on carbohydrates
(CHO) counting (V1), or with a personalized, advanced bolus (V2) calculated from insulin/Kcal derived
from Fats and Proteins (FPU). Post-prandial glucose was continuously monitored; glucose incremental
areas (iAUC), glucose peak and time to peak, and estimated change from V1 to V2 from repeated-
measures models were computed. Each patient fulfilled validated questionnaires on quality of
life, knowledge about diabetes and CHO counting.

Results :

After the educational program, a reduced iAUC (0-80 min: -306, p=ns; 40-80 min: -400,
p=0.07) due to greater (p=0.03) and prolonged double-wave insulin boluses was observed. Blood glucose
peak and time to peak were also reduced. Moreover, improvements in the psycho-affective dimension,
as well as in the alimentary knowledge were detected.

Conclusion:

Therefore, a personalized educational program on CHO + FPU counting together with insulin
bolus management can improve glycemic control during social consumption of alcohol, with positive
reflections on the psycho-affective dimension. Further studies are mandatory to confirm such preliminary
results.
Electroanalytical Methods for Determination of Calcium Channel Blockers
Authors: Ağın Fatma
Published: May 2019

Background:

Calcium Channel Blockers (CCBs) are widely used in the treatment of cardiovascular and ischemic heart diseases in recent years. They treat arrhythmias by reducing cardiac cycle contraction and also benefit ischemic heart diseases. Electroanalytical methods are very powerful analytical methods used in the pharmaceutical industry because of the determination of therapeutic agents and/or their metabolites in clinical samples at extremely low concentrations (10-50 ng/ml). The purpose of this review is to gather electroanalytical methods used for the determination of calcium channel blocker drugs in pharmaceutical dosage forms and biological media selected mainly from current articles.

Methods:

This review mainly includes recent determination studies of calcium channel blockers by electroanalytical methods from pharmaceutical dosage forms and biological samples. The studies of calcium channel blockers electroanalytical determination in the literature were reviewed and interpreted.

Results:

There are a lot of studies on amlodipine and nifedipine, but the number of studies on benidipine, cilnidipine, felodipine, isradipine, lercanidipine, lacidipine, levamlodipine, manidipine, nicardipine, nilvadipine, nimodipine, nisoldipine, nitrendipine, diltiazem, and verapamil are limited in the literature. In these studies, DPV and SWV are the most used methods. The other methods were used less for the determination of calcium channel blocker drugs.

Conclusion:

Electroanalytical methods especially voltammetric methods supply reproducible and reliable results for the analysis of the analyte. These methods are simple, more sensitive, rapid and inexpensive compared to the usually used spectroscopic and chromatographic methods.
A QoS Based Formal Model for Software Defined Network
Authors: Srivastava Vivek , Pandey Ravi Shankar
Published: May 2019

Background & Objective:

Software-Defined Networks (SDN) decouple the responsibility
of data plane, control plane and aggregates responsibilities at the controller. The controller manages
all the requests generated from distributed switches to get the optimal path for sending data
from source to destination using load balancing algorithms. The guarantee of packet reachability is a
major challenge in real time scenario of a SDN which depends on components of network infrastructure
as switches, a central controller, channel capacity and server load. The success of this aggregation
and packet reachability demand is a high Quality of Service (QoS) requirement in terms of
throughput, delay and packet loss due to high traffic volume and network size. This QoS has two
perspectives one is required other is a computation of real QoS value.

Methods:

In this paper, we have presented the QoS based formal model of SDN to compute and to
investigate the role of the real QoS value. This formal model includes QoS on the basis of packet
movement hop by hop which is a real-time QoS. The hop by hop packet movement reliability has
been computed using channel capacity and server load which is an abstraction of throughput, delay,
and packet loss. The effect of channel capacity and server load can be varying using different values of
the weight factor. We have also considered an equal role of channel capacity and server load to compute
reliability. This QoS helps to the controller to match with required QoS to decide the better path.

Conclusion:

Our results finds the reliable path based on channel capacity and server load of the network.
Also, results showed that the reliability of the network and controller which are based on the
reliability of the packet delivery between two nodes.
ALGORITHMS FOR SEGMENTING A DIGITAL IMAGE OF AN UNKNOWN OBJECT AND ISOLATING ITS CONSTRUCTIVE ELEMENTS ON A LOW-CONTRAST AFTERDETECTOR IMAGE
Authors: Lavrov V. V. , Luchkin R. S. , Nemykin O. I. , Prokhorov M. E. , Ryndin Yu. G.
Published: May 2019

Algorithms for segmenting an optical image (OI) of an unknown remote object and isolating its main constructive elements on a low-contrast image are considered. The processing obtaining after the performed rank filtration of the image of the object, the description of which is specified in the form of a set of bitmaps formed at different threshold intensity levels, is carried out in two stages. At the first stage, the problem of segmentation of binary images is solved using the methods of graph theory and the apparatus of mathematical logic. With the participation of the analyst, the most qualitative image is picked out in the representation of the set of related domains. With Using the representation of the obtained OI in the form of a graph forest, the task of isolating the basic structural elements of the object is solved at the next stage of processing. Formations are made of estimates of their parameters, invariant to affine transformations and to scaling of the image intensity. These estimates are expedient for use in recognition.
QUALITY ASSURANCE OF SOFTWARE AND HARDWARE COMPLEXES FOR DATA STORAGE AND PROCESSING CENTERS
Authors: Ivakin Ya. A. , Morozov S. A. , Balashov V. M. , Smirnova M. S.
Published: May 2019

The article analyzes and presents an analysis of the structure of software and hardware systems, reviewed the documentation of regulatory and technical regulation, identified the main performance indicators for software and hardware systems for data storage and processing centers. A generalized representation of the software and hardware structure of software and hardware complexes for data centers in the form of an embedded scheme was developed and presented. Also, the article identifies and structures the basic or typical services supported by modern software and hardware systems of data centers. The role and place of software and hardware complexes of data centers in information support of state and corporate governance bodies are determined. The main indicators of the quality of the functioning of the software-hardware complexes of data center are presented in the work when hosting services are provided. The problem of creation of the normative and technical base and scientific and methodological tools for assessment and improvement of the quality of the corresponding software and hardware complexes is revealed. The structure of software and hardware systems, reviews the documentation of regulatory and technical regulation, determines the main performance indicators for software and hardware systems for data storage and processing centers.
METHODICAL ASPECTS OF EVALUATION OF CURRENT CHARACTERISTICS OF RADAR
Authors: Dikij V. I. , Zaripov D. I. , Kuptsov I. V.
Published: May 2019

Estimation of the TTX of radars used to monitor space objects is associated with great material and time costs. In this article, the methodological approaches to the assessment of some technical characteristics of the radar (control zone, radar potential, throughput, the rate of issuance of coordinate measurements, minimum tracking time, minimum RCS value of detectable space object) are presented based on the results of a posteriori statistical processing of the received trajectory measurements. The results of the approbation of these methods are given.
METHOD OF COMPENSATION OF IONOSPHERE ERRORS OF SPACE OBJECTS COORDINATES DEFINITION BY MEANS OF TWO POSITION RADAR OBSERVATION
Authors: Galkin P. S. , Lagutkin V. N.
Published: May 2019

The algorithm of estimation and compensation of ionosphere influence on the measurement of parameters of the motion of space objects in two-position radar system with account of radio physical effects depending on elevation angles and the operating frequency is developed. It is assumed that the observed space object is traсked object, the orbital parameters which are well known, including the dependence of the velocity of the point on the orbit, and the uncertainty of the current coordinates of the object is caused mainly by forecast error of its position of in orbit (longitudinal error). To estimate the true position of space object in the orbit and the parameter, determining the influence of the ionosphere, a joint optimal processing of measurement of ranges to the object, obtained by two separated radars, taking into account the relevant ionospheric propagation delays and available a priori data on observable object trajectory. Estimation of unknown parameters are obtained on the basis of the criterion of maximum a posteriori probability density for these parameters, taking into account the measured and a priori data. The task of searching for maximum a posteriori probability density is reduced to task of searching of minimum weighted sum of squares, for the solution of which the cascade algorithm of iteration through is implemented in the work. Estimation accuracy of the position of space objects in orbit after compensation of ionosphere influence have been studied by Monte-Carlo method. Dependencies of mean square error of the position estimation of space objects upon elevation angles, operation frequency and solar activity have been obtained. It is shown that the effectiveness of the algorithm increases with the spatial base of measurements (for a fixed orbit of the object).
METHOD FOR ESTIMATING PARAMETERS OF GENERALIZED MODEL OF LUMINOSITY OF SPACE OBJECTS BASED ON DATA FROM DIFFERENT RANGES
Authors: Gundrova E. I. , Lukyanov A. P. , Pruglo A. V. , Ravdin S. S.
Published: May 2019

Previously, the authors have proposed a generalized model for estimating the distribution law parameters of luminosity of space objects, assuming that not only successful but also unsuccessful measurement results are taken into account. Estimation was done on the data of observations under similar conditions: phase angle, range, sensibility of the telescope. The algorithm under such limitations was tested on model data and real measurements. Therefore, obtained results showed that algorithm did not fit for cases of changing range of space objects. In this work, the new algorithm, that allows to merge information from different ranges to the observed space object, is proposed. In this case, luminosity values are reduced to the ones at a reference distance of 1000 km considering sensibility of the telescope. To obtain estimates of the parameters the Cramer-Mises-Smirnov criterion is used. This algorithm was tested on model data and results of its work on real data were obtained. The data showed correct work of the algorithm and also confirmed the practicability of organization the registration of unsuccessful measurements.
SPACE OBJECT ORBIT ESTIMATION AT LIMITED ANGLE MEASUREMENTS ERRORS
Authors: Kolessa A. E. , Sokolov I. S.
Published: May 2019

The problem of a space object orbit estimation and determination of region with minimum volume, which contains with guarantee orbit state vector, is considered. Measurements are provided by the telescope and estimation of angle measurements errors are limited in absolute value. The significant dependence of the guaranteed area size on the choice of coordinate system for observations is found, the algorithm for determination of the minimum volume area is suggested based on the simplex-method. In addition the comparison analysis of results of created algorithm with known ones based on various methods (guaranteed and probabilistic) is presented. The developed algorithm is able to give more precise results in several cases in comparison with other known algorithms.
METHOD FOR ESTIMATING ERRORS IN MEASURING INSTRUMENTS BY THE SPACE CATALOGUE ORBITS
Authors: Sorokin K. V. , Sunarchina E. A.
Published: May 2019

Improvement of orbits precision is one of the most important tasks of space surveillance catalogue maintenance. The solution of this problem is directly related to an adequate consideration of the errors of the coordinate information from the measuring instruments. The article consideresd a new method for estimating the precision of measuring instruments on the catalog orbits. To carry out such analysis, in PJSC «VIMPEL» special technological program was created. Main results of a study of radar errors with orbits of space surveillance catalogue was presented. Also, the results were compared with data of measuring instrument's calibration software complex. This software complex provides determination of satellite's position with errors less than 10 m. A new dynamic model of measuring instrument errors is proposed.
CALCULATION OF THE DEPENDENCE OF THE DISTANCE TO THE LOCATED OBJECT FROM THE CORNER POSITION OF THE VEHICLE LINE
Authors: Artyushenko V. V. , Nikulin A. V.
Published: May 2019

To simulate echoes from the earth’s surface in the low flight mode, it is necessary to reproduce reliably the delayed reflected sounding signal of the radar in real time. For this, it is necessary to be able to calculate accurately and quickly the dependence of the distance to the object being measured from the angular position of the line of sight of the radar station. Obviously, the simplest expressions for calculating the range can be obtained for a segment or a plane. In the text of the article, analytical expressions for the calculation of range for two-dimensional and three-dimensional cases are obtained. Methods of statistical physics, vector algebra, and the theory of the radar of extended objects were used. Since the calculation of the dependence of the range of the object to the target from the angular position of the line of sight is carried out on the analytical expressions found in the paper, the result obtained is accurate, and due to the relative simplicity of the expressions obtained, the calculation does not require much time.
MAXIMUM PERMISSIBLE INPUT POWER OF DISCRETE TUNABLE RESONATOR ON THE CUTS OF HOMOGENEOUS LONG LINES
Authors: Unru N. E.
Published: May 2019

In the article the questions of building of discrete tunable resonator on segment of homogeneous long line in terms of the level of permissible input power are consider. For the first time a analytic expressions that allow calculating the maximum input power of a discrete tunable resonator on a segment of homogeneous long line are obtained. Analytic expressions for the solution of the problem of synthesis of a discrete tunable resonator - the calculation of the requirements for the parameters of pin-diodes and the tuning capacitors for the required level of maximum input power also are presented. The results of experiments and calculations confirm the possibility of constructing powerful tunable resonators and filters based on them with a short tunable time.
METHODICAL APPROACH TO AD WMSE FLEET TECHNICAL STATE PREDICTION FOR NEAR-TERM AND LONG-TERM OUTLOOK
Authors: Silkin A. T. , Belorozov M. S. , Makarov O. V.
Published: May 2019

Availability of a set number of operationally ready pieces of weapons and military equipment is the most important for the forces. A degree of conformity of the available number of serviceable (operable) pieces of the AD WMSE incorporated in the WMSE fleet with the required number for the set planned (predicted) period is used as a collective index of the AD WMSE fleet readiness degree. Modern automated informational technologies are actively used when performing tasks related to effective management of the AD WMSE fleet operation, including planning and predicting tasks. This allows for increase of operational control and efficiency of the WMSE fleet technical state predictions. In its turn, this fact requires further improvement of methods aimed at the AD WMSE fleet technical state prediction for the set operational periods taking into account different strategies of replenishment (renewal) of the WMSE fleet, organization of the WMSE pieces operation, and limitations on financing. Main standard documents determining the AD WMSE development prospects for the near-term and long-term outlook are the State Armament Plan (SAP) which is developed for a 10-year period and a State Defence Order which specifies the SAP for a 3-year period. The article considers options of preparing initial data in order to predict the AD WME fleet state for the future period taking into account different strategies of the WME pieces retirement which have expired service life and exhausted lifespan. The options of forming predictive assessments with regard to the available pieces of the AD WME in case of different financing variants of purchases and measures related to modernization, operation and repair of the AD WME are considered.
ASPECTS OF PROTECTION OF DEVELOPMENT ENTERPRISE’S RIGHTS TO INTELLECTUAL PROPERTY ITEMS
Authors: Strakhov A. F.
Published: May 2019

When performing research, development, and engineering (RD&E) financed using state, regional, or municipal budget funds, legal relations between a customer and a RD&E contractor with regard to ownership of a created intellectual property are regulated by Part 4 of the Civil Code of the Russian Federation [1]. The intellectual property includes patentable innovative solutions which are qualified as intellectual property items. According to the applicable legal standards and law enforcement practice, patent protection obligations with regard to the created intellectual property items are imposed on the RD&E contractors. However, patent right holders with regard to these intellectual property items are the RD&E customers. As a result, the RD&E contractors face several difficulties, delays, and limitations with regard to patenting the intellectual property items and do not obtain necessary privileges to the full extent in connection with patenting the created intellectual property items. This article analyses the applicable procedure for distribution of the rights and obligations between the contractors and customers of the RD&E with regard to the patent protection of the created intellectual property items. Using experience of JSC Principle Production and Technical Company Granit as an example, a possibility of protecting RD&E contractors' interests by pre-emptive patenting of the intellectual property items prior to RD&E activities start is explained.
DETERMINATION OF RADIO SOURCES LOCATION BY THE METHOD OF "IMAGINARY BASE" WHEN USING THE LINEAR MODEL
Authors: Petrov Yu. V. , Bakaras S. I. , Yukhno S. A.
Published: May 2019

This article presents the expressions which allow evaluating the potential accuracy of radio source location by the method of «imaginary base» when using the linear model of changing the bearing on it. The concept of the method of «imaginary base» is to be used in solving the triangulation problem not only of measuring bearing, but also their extrapolated values at a certain time interval. Potential characteristics is determined by accuracy, dynamic and geometrical factors, bearing measurement and extrapolation times. The article shows that when using a linear model, there are limitations both on the time of measuring bearing and on the time of extrapolation. It will be because of the increase in the variance of the error of estimating the distance. Limiting of series decomposition members number of non-linear bearing change dependence from time there are. It depends on the speed of changing bearing (depends on the range and speed) and the initial bearing (depends on the track angle). Extrapolation over long time intervals is possible only at long distances and at relatively low speeds.
MODAL ANALYSIS OF LINEAR ACTUATOR
Authors: Gorbunov A. V. , Zheltyshev O. I. , Yakovenko N. G.
Published: May 2019

The question of checking the linear drive for resistance to resonance in the structure of the precision positioning mechanism for space applications - hexapod, when it is taken to a near-earth orbit is considered. Calculation of the values of the natural frequencies of the structure is carried out by the finite element method using CAD. The application of the modal analysis of structural elements is presented on the example of the linear actuator case for evaluating the resistance to resonance as one of the criteria for selecting a material. The comparative results of the modal analysis for the variants of the linear actuator housing are presented. Modal analysis of the linear drive is carried out, calculated frequencies and forms of natural oscillations are presented. The initial data for the harmonic analysis of the linear drive are obtained. The compliance of the developed linear drive with the specified requirements has been confirmed.
ABOUT MATERIALS OF THE THERMOEMISSION COOLING SYSTEM OF BLADES OF TURBINES OF GAS TURBINE CONVERTERS OF AEROSPACE CRAFTS OF RADIO-ELECTRONIC REMOTE SENSING OF THE EARTH
Authors: Kolychev A. V. , Kernozhitskiy V. A. , Levikhin A. A.
Published: May 2019

Rated estimates of effect of application of the Thermal electron emission Way of Cooling (TWC) of blades of turbines (BT) of the gas turbine converters (GTC) of the Space Aircraft (SA) developed in in D. F. Ustinov Baltic State Technical University «VOENMEH» are given in the present article. Relevance of development of TWC is confirmed by the fact that now in the Russian Federation development of the SA platform with the energy basis at the heart of which the principle of gas turbine transformation is conducted. However, because of low reliability of its basic elements - blades of turbines in operating conditions, it is necessary to reduce temperature in installation that reduces efficiency and increases the weight and dimensions of SA in general. It means that taking into account opportunities of modern means of removal, opportunities for equipment of SA of the radio-electronic equipment are reduced and characteristics of SA with radio equipment in general decrease. Improvement of these characteristics requires increase of reliability of blades of turbines and increase on this basis of temperature of GTC, its efficiency with simultaneous decrease in weight and dimensions. But in this case it is supposed that turbine blades will be made of the ceramic materials functioning in the environment of the inert gases heated from onboard source of heat energy. One of problems at the same time is emergence of temperature gradients, tension and deformations that can lead to emergence of cracks. However, if to execute ceramic blades from metalsimilar connections (borida, carbides, alloys of borid and carbides) using TWC, then opportunity essential (more, than twice) decrease in both TB temperature, and temperature differences, and tension in TB design appears. In article it is also shown that decrease in temperature stresses in design of hot elements at equivalent heat load is reached due to fundamental properties of thermionic emission, namely thanks to dependence of intensity of thermionic emission and electronic cooling on temperature.
FEATURES OF PROCESSING OF SPECIAL SITUATIONS IN HIGH SPEED RECEIVERS OF SERIAL CHANNELS
Authors: Domozhakov D. A. , Kondratenko S. V.
Published: May 2019

The review and comparison of the ways of handling special situations, occurring at the input of high-speed signal receivers from serial communication lines, is presented. Particular attention is paid to the situation when the amplitude of the input signal is below a predetermined threshold and the problem of early detection and indication of this situation at the physical level (in the interface part of the receiver) is solved. The handling of special situations is provided in popular serial transmission standards, but its practical implementation for high-speed transceivers at the physical level is difficult due to the lack of ready-made solutions that take into account the entire set of requirements for the special situations processing subsystem. Proceeding from the formulated requirements, the analysis of possible solutions is justified and the structure of the special block for detecting a special situation of this type that produces the appropriate signal in real time is justified. The proposed special situation detection unit is an auxiliary range comparator that operates in parallel with the comparator in the main channel, does not affect the duty cycle of the signals in this channel and is built on the basis of asymmetric differential stages in the composition of two modified comparators. It is shown that such a solution, in combination with the envelope detector at the output of the auxiliary channel, makes it possible to provide stable thresholds for the operation of the receiver and the generation of a correct (non-destructive) signal indicative of the occurrence of a special situation.The results of modeling such a block in the CML receiver made using 90 nm CMOS technology and operating at a speed of not less than 3 Gbit/s are presented.
USING OF PROJECTIVE TRANSFORMATION IN CREATING NEURAL NETWORK DATA SET
Authors: Kuzmina V. V. , Khamukhin A. V. , Kononova A. I.
Published: May 2019

An experience of the neural network data set creation automation, which is used for license plate recognition, has been presented. The main problem of neural network training with data, obtained by nature filming is that collecting require amount of data takes a long time, beside this neural network does not effectively recognizer rare license plate formats after training. The main objective of the work is to improve recognition quality and training speed of the neural network. To achieve this objective, training data set is formed from automatically generated license plate images. Projective transformation are used for filming distortion imitation. The data set, generated in this way, includes all license plate standards, and the rare kinds percentage is enough to effectively recognize them. Using of the presented generator allows not only to significantly accelerate training data set creation, but also to improve rarely used standards of license plates recognition quality.
Engaged and Activist Scholarship for Socio-Economic Development in South Africa: A Conceptual Appraisal
Authors: Mbecke Paulin
Published: May 2019

The debate around scholarship (engaged and activist) is new in South Africa. Currently, the practice of engaged scholarship and activist scholarship is poor or quasi-inexistent, yet, it is believed that these two approaches can contribute to human rights activism which favours socio-economic development. This paper identifies the patterns and principles of engaged scholarship and activist scholarship and their connection with socio-economic development. It argues that effective engaged and activist scholarship programmes can contribute to and facilitate socio-economic development. Thus, the paper suggests a model outlining four key principles forming a conceptual framework for an effective engaged scholarship and a supporting activist scholarship model that facilitates the awareness and participation of communities in socio-economic development efforts.
The State of Female Activities in Iran and the Internet
Authors: Karimi Sedigheh
Published: May 2019

The rapid development of Internet and communication technologies raises the question of what role these media and communication interfaces play in social and political movements and development in individual countries. Although activities in cyberspace, including blogging, participation in social networks and other facilities provided by the Internet for its users are a new phenomenon, they have profound effects on social and political relations in the communities involved. In the information era, Internet is an important part of social movements in democratic societies and local communities. When the government blocks other ways to mobilization, Internet may bring like-minded people together and help them to find support for action. Internet has provided a new space for social movements and the effect of the virtual activities of the users on the actions and, often on the lack of social movements is of high importance.

Meanwhile, the Iranian women’s movement, like other social movements in contemporary Iran, realizes the impact and position of cyberspace and has made use of it. Many activists, for whom other ways for expressing their demands have been blocked, have entered this space and taken advantage of it for expressing their opinions and communicating information to other people. In fact, the dominant socio-political forces and the atmosphere of repression, and fear have led many Iranian women to use the virtual space to campaign for women’s empowerment and equal rights. They have realized that the Internet may inform the outside world of the movement’s goals and activities and facilitate maintaining contact with other members of the movement. In fact, the open space that provides a platform for sharing information and has given the chance to the Iranian women’s rights activists to perform their activities in a space with a decentralized structure where there is less pressure than there is in the real world. Campaigns formed following the cyberspace market boom indicate that cyberspace has indeed ushered in a new era in the history of the Iranian women’s movement.
The present study, covers the period from 2005 to 2017, provides an analysis of the role of the Internet in the activities of the women’s movement and explores the extent to which cyberspace has been assisting the women’s movement in achieving its objectives. By interviewing 50 active women inside Iran, the article investigates whether there has been successful interaction between cyberspace and the Iranian women’s social movement resulting from a dynamic adaptation between functions of social and political groups in the real world and the virtual world. It also examines how factors such as social participation, increasing awareness, changing beliefs, traditional views of women and social mobility have been affected by the application of the Internet, and whether cyberspace has been able to make women’s voices heard in Iran’s patriarchal society.
Aplicaciones de la Segunda Ley de Newton
Authors: Becerra Córdova Guillermo
Published: May 2019

En los cursos de Física, donde se incluya a la Mecánica, la Dinámica es parte esencial para explicar el movimiento de los cuerpos. El movimiento de un cuerpo queda determinado por su interacción con el medio ambiente a ésta se le denomina fuerza. Para que un cuerpo experimente una aceleración es necesario que la fuerza que se ejerza sobre él sea mayor a cero. De lo contrario el cuerpo no experimentará una aceleración y permanecerá en estado de reposo o en movimiento rectilíneo uniforme. La segunda ley de Newton establece que la suma vectorial de todas las fuerzas que actúan sobre un cuerpo es igual a su masa multiplicada por su aceleración. Así, para una masa dada, la aceleración que experimenta un cuerpo es directamente proporcional a la fuerza ejercida sobre éste y, para una fuerza dada, la aceleración que experimente un cuerpo es inversamente proporcional a su masa. En este trabajo se presentan sistemas de simulación de fenómenos en los cuales se aplica la segunda ley de Newton. El objetivo de este trabajo es ponerlo a disposición para los cursos de Mecánica Clásica en los diferentes bachilleratos a distancia.
Ciencias de la Salid I: El trabajo interdisciplinario
Authors: Navarro León Carlota Francisca
Published: May 2019

Se presenta una reflexión sobre el trabajo colaborativo e interdisciplinario que realizaron profesores expertos para construir contenido, actividades y estrategias de aprendizaje y evaluación para la asignatura de Ciencias de la Salud I, del Plan de Estudios del Bachillerato a Distancia.

El principal objetivo de este enfoque didáctico, que parte de la experiencia y el conocimiento de docentes expertos en las diferentes áreas del saber, es que los estudiantes logren aprendizajes integrales e interdisciplinarios, relacionen lo que están estudiando con otras disciplinas y puedan encontrar respuestas tanto a situaciones problema escolares como de la vida cotidiana.
Un pequeño comentario sobre tres puntos
Authors: Herrera María del Coral
Published: May 2019

Se propone reflexionar mínimamente sobre algunos ámbitos importantes de la práctica docente en la modalidad a distancia, y el beneficio de que los asesores lo tomaran en cuenta para la relación con el dicente, haciendo énfasis en la necesidad de apropiación del conocimiento como una vía de formación continua y vital de los humanos.
Educacion en Linea en la Universidad TecMilenio
Authors: Nava Guerra Candy
Published: May 2019

La Universidad TecMilenio del Sistema Tecnológico de Monterrey es un sistema con presencia en 21 estados del país, a través de 39 campus y un Campus en Línea. Fue fundado en 2002 para formar personas que se integren rápidamente al mercado laboral con las habilidades y la certificación en competencias que actualmente requieren las empresas. El Instituto Tecnológico y de Estudios Superiores de Monterrey (ITESM) es una universidad privada fundada en 1943 en la ciudad de Monterrey, Nuevo León, México. Fue la primera universidad de América Latina en conectarse al Internet en 1989, además de ser la institución encargada de manejar el dominio de registro del país a través de NIC México ubicado en el campus de la ciudad de Monterrey.
Bachillerato Tecnológico Bivalente a Distancia del Instituto Politécnico Nacional
Authors: Torres León Mónica Rocío , Bustamante Díez Yoloxóchitl
Published: May 2019

A fin de compartir la experiencia del Instituto Politécnico Nacional en el diseño, desarrollo y puesta en operación del Bachillerato Tecnológico Bivalente a Distancia (BTBD), en el presente trabajo se hace un recuento de las principales características de sus propuestas pedagógica y operativa, así como de los hallazgos y aprendizajes derivados de la vivencia del proceso de admisión e inicio de cursos de la primera generación.
Bachillerato a Distancia del Sistema de Universidad Virtual. Universidad de Guadalajara
Authors: Ochoa Reynoso Rosa Marcela
Published: May 2019

La incorporación de un enfoque educativo centrado en el aprendizaje y por competencias, el uso de Tecnologías de la Información y Comunicación (TIC´S) y la necesidad de ampliar la cobertura en el Nivel Medio Superior para atender a grupos socialmente vulnerables, entre otros, han sido factores de creación del Bachillerato a Distancia.

El objetivo general del Bachillerato a Distancia es ofrecer a todas las personas que han completado la secundaria la oportunidad de cursar y obtener su certificado de bachillerato, avalado por la Universidad de Guadalajara. Este programa está concebido como una alternativa de educación media superior para todos los interesados en cursar o concluir sus estudios de bachillerato, pero que no pueden asistir a un aula debido a sus responsabilidades sociales, familiares, personales y/o su ubicación geográfica.

El Bachillerato a Distancia del Sistema de Universidad Virtual es pionero en el país en ofrecer un programa educativo por competencias, que es ya la tendencia de programas de formación en México y en el mundo. Entre las competencias que el estudiante de este plan de estudios adquiere están: responsabilizarse de su propio proceso de desarrollo, comunicarse de manera eficiente, aplicar conocimientos científicos en su interacción con el entorno, adoptar prácticas para cuidar la salud y el medio ambiente, y apreciar las manifestaciones artísticas. Una de las competencias que el estudiante de bachillerato del Sistema de Universidad Virtual obtiene --a diferencia de la modalidad presencial- , es la utilización de las tecnologías de la información y la comunicación en la vida cotidiana: ser estudiante a distancia brinda la posibilidad de autogestionar un aprendizaje continuo en esta era de tecnología y conocimiento.
¿CÓMO MANEJAR LA ASESORÍA EN LA PRÁCTICA DOCENTE?
Authors: González García Bernardo
Published: May 2019

Se analiza la actitud del docente en la práctica cuando los estudiantes acuden a él para una asesoría en la unidad de aprendizaje de Física. Se hace una propuesta de cómo hacer más eficiente esta práctica para que el alumno se quede con un aprendizaje sólido y distinto al que adquiere cuando estudia sólo para aprobar la asignatura.
Bachillerato Virtual del Sistema de Universidad Virtual de la Universidad Autónoma del Estado de Hidalgo
Authors: González Farfán Érika , Rabling Conde Guillermo E.
Published: May 2019

La educación formal es una de las principales manifestaciones de crecimiento para el ser humano, por ello la Universidad Autónoma del Estado de Hidalgo, a través de su Sistema de Universidad Virtual brinda una nueva modalidad en su oferta educativa 2009: el aprendizaje en línea. Con un sistema propio dentro del modelo educativo centrado en el estudiante, utilizando las tecnologías de información como una herramienta que propicia la flexibilidad de integración de contenidos y actores en el proceso fundamental de enseñanza–aprendizaje. El Bachillerato Virtual, específicamente, fue creado con el fin de responder tanto a los requerimientos y exigencias de las instituciones de educación superior, como a los diversos sectores de la sociedad; se trata de una opción real para quienes aspiran a una educación profesional, pero que no pueden acceder o continuar en los sistemas presenciales. Su Misión es formar integralmente a los estudiantes en una modalidad no escolarizada, con conocimientos de cultura general, habilidades y valores, con una actitud crítica, creativa, emprendedora, solidaria tolerante y comprometida con la conservación del medio ambiente, que les permita la solución de los problemas de la vida, capacitándolos competitivamente para acceder exitosamente a estudios de nivel superior y a su entorno social.
La importancia de la motivación en el bachillerato a distancia
Authors: Alarcón Aguilar Ricardo
Published: May 2019

Participar como asesor en el Bachillerato a Distancia del Instituto Politécnico Nacional, aunado a la experiencia del sistema presencial, constituye un gran aprendizaje. Se identificó la importancia que tiene la motivación a través de un lenguaje adecuado en grupos de ambas modalidades (presencial y a distancia) para lograr un cambio positivo entre nuestros estudiantes.
Del diseño de programas, materiales y recursos. La experiencia del escritorio al aula
Authors: Echauri Vargas Erika Guadalupe
Published: May 2019

Dentro del diseño de un programa académico, debe considerarse el entorno del mismo, los insumos y los actores que serán directamente vinculados con la aplicación del programa, de esta manera “Autodeterminación y Aprendizaje” al tratarse de una Unidad de Aprendizaje Integrada (UAI) del Área Interdisciplinaria (AI) de “Sujeto y Aprendizaje”, se procuró diseñar estrategias que permitieran al estudiante analizar críticamente el proceso de construcción de su identidad y diseñar una trayectoria de vida acorde con sus habilidades, aptitudes y necesidades vocacionales. Buscando, mediante la metodología sugerida, el desarrollo de competencias, entrelazando los contenidos temáticos para lograr que el alumno interiorice los conocimientos convirtiéndolos en saberes prácticos, teóricos y vivenciales, que por consecuencia lleve de manera directa a los tres momentos de la evaluación: diagnóstica, sumativa y formativa. En conclusión, el desarrollo de programas para ambientes mixtos, es necesario que busque la mediación y asesoría permanente por parte del asesor, no dejando de lado la flexibilidad del mismo, la búsqueda constante de los momentos de autogestión y autoinstrucción respetando la diversidad de la población en necesidades personales y tiempos. Brindando la posibilidad de la retroalimentación continua mediante el contacto Asesor-Alumno, Alumno-Alumno, Asesor-Asesor.

 
“Así viví mi Bachillerato a Distancia”
Authors: Herrera Márquez Alma
Published: May 2019

Lo que hace de la lectura de este libro una experiencia apasionante es que está conformado por 50 historias autobiográficas cuyo entramado sigue un orden lógico, articulado a partir de la selección de algunos acontecimientos, personajes e interacciones. Pero dicho entramado atrapa la atención de tal forma que, tras la lectura, la serie de acontecimientos narrados en cada historia, se recombina en la memoria del lector para quedar ordenada en una secuencia que tiene múltiples consecuencias.
Diseñar para aprender: redes sociales en línea como un entorno de clase
Authors: Casey Gail , Evans Terry
Published: May 2019

Este artículo presenta las nociones de emergencia, conexiones y diseños para aprender con el fin de conceptualizar las interacciones de estudiantes de bachillerato al usar redes sociales en línea como entorno de aprendizaje. Establece vínculos con las teorías del caos y de la complejidad, así como con patrones fractales al reportar sobre una investigación de la primera autora. Dicho estudio se realizó en Australia mientras trabajaba en un bachillerato público y completaba su doctorado. El estudio investiga el uso de una red social en línea Ning como un entorno de aprendizaje compartido por siete grupos de clase y examina las reacciones y actividad en línea de los

estudiantes al usar una variedad de media social y herramientas de la Web 2.0.

Los autores usan el enfoque de Graham Nuthall (2007) llamado “lente en el aprendizaje” para explorar los procesos sociales y culturales de esta aula virtual compartida. El artículo utiliza un extenso cuerpo de conocimiento y analiza los procesos de aprendizaje en aula para conceptualizar y analizar datos a lo largo del ciclo de investigación acción. Discute las implicaciones pedagógicas que surgen del uso de las redes sociales y, al hacerlo, cuestiona los modelos tradicionales de enseñanza y aprendizaje.

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 Este artículo ha sido reproducido de la Revista The International Review of Research in Open and Distributed Learning (IRRODL). Volumen 12, Número 7; utilizando una licencia Creative Commons Attribution International 4.0. © 2011. Autores: Gail Casey, Terry Evans.
Universidad de la Tierra en Oaxaca, A. C.: aprender sin escuela
Authors: Beltrán Arruti Sergio
Published: May 2019

En el presente artículo el autor presenta una reflexión personal sobre su experiencia y aprendizajes adquiridos durante la creación la Universidad de la Tierra, A.C. como una alternativa educativa a quienes la modalidad presencial no puede atender.
Influencia de los estilos de aprendizaje y la autorregulación en el rendimiento escolar de los alumnos del Bachillerato a Distancia del Estado de México
Authors: García Salas Lilia , Ortega Massé Juan Carlos
Published: May 2019

métodos de educación dentro del proceso enseñanza-aprendizaje han cambiado, aunado a esto, el manejo de nuevas tecnologías en apoyo al área educativa ha generado cambio en los paradigmas educativos, conceptualizando al alumno con diferentes características y habilidades dentro de dicho proceso. Intervienen diversos factores tanto sociales como personales, en estos últimos debe considerarse que el alumno cuenta con diversas estrategias de estudio influenciadas por los estilos de aprendizaje y la capacidad de autorregulación para generar una enseñanza significativa. El presente estudio tuvo como objetivo identificar la relación entre los estilos de aprendizaje y la autorregulación en el rendimiento académico de alumnos que se encuentran en esta modalidad a distancia de nivel medio superior en la Universidad Digital del Estado de México, Centro de Atención y Evaluación 09 “San Pedro Xalostoc” del municipio de Ecatepec. Los resultados demuestran que existe una correlación entre estrategias de autorregulación y rendimiento, no así entre estilos de aprendizaje y rendimiento, además de que se vislumbran diferencias no tan significativas entre sexos. Concluyéndose que los alumnos que cuentan con más claras y mejores estrategias de autorregulación tendrán un mayor rendimiento académico, y con ello habilidades para un aprendizaje significativo.