bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-cusped postcanine teeth are associated with zooplankton feeding in phocid seals
Authors: Ishihara U , Miyazaki N , Yurkowski DJ , Watanabe YY
Published: January 2024

Tooth morphologies often reflect diet in animals. Among marine mammals, a well-known example is the krill-feeding crabeater seal Lobodon carcinophaga, in which complex, comb-like postcanine teeth function as a sieve by retaining krill inside the mouth while expelling water. However, information on tooth morphology and function is scarce for other seal species. A recent bio-logging study found that Baikal seals Pusa sibirica feed on tiny pelagic amphipods at remarkably high rates with highly multi-cusped postcanine teeth, highlighting the need for comparative analyses on tooth morphologies and diets in phocid seals. Here, we quantified postcanine tooth morphology for 13 seal species based on museum skull specimens, with a particular focus on Baikal seals and their related species (genera Pusa and Phoca). Pusa species, including Baikal seals, had more specialized multi-cusped postcanine teeth than Phoca species, reflecting higher zooplankton proportions in their diets. Postcanine teeth of Baikal seals exhibited the highest degree of specialization among Pusa, even when the effect of age-related wear was controlled for. This result agrees with the highest zooplankton preference in this species. Further, we found a strong positive correlation between the degree of specialization in postcanine teeth and zooplankton reliance across phocid seal species. Our findings indicate that the functional role of multi-cusped postcanine teeth as a sieve is not limited to crabeater seals but prevails in many phocid seals feeding on zooplankton.
Intraoperative imaging, navigation and radiation management in aortic and peripheral endovascular procedures
Authors:   , Jansen Marloes Marleen
Published: January 2024

Endovascular techniques are essential in treating vascular conditions, to ensure safe and rapid recovery, particularly for elderly and vulnerable patients. Approximately 60% of vascular treatments currently employ endovascular techniques. Within the expanding field of endovascular techniques, there is a growing demand for advanced imaging technology. The current reliance on fluoroscopy has limitations, including exposure to radiation and limited 3D interpretation.

This dissertation primarily focuses on reducing radiation exposure and optimizing intraoperative imaging and navigation, with an emphasis on introducing Fiber Optic RealShape (FORS) technology developed by Philips Medical. FORS enables real-time 3D visualization of guidewires and catheters while minimizing radiation use. This innovation promises significant progress in the quality of endovascular treatments.

The dissertation also explores other methods to decrease radiation exposure, such as using radiation-absorbing cloths, and provides guidelines for optimizing the operating room setup. Additionally, it offers a comprehensive overview of current imaging and navigation in peripheral endovascular procedures, delving into image fusion—a technique combining conventional real-time fluoroscopy with 3D imaging data. The study focuses on artery displacement during operations and the challenges it poses to guidance accuracy.

The dissertation underscores the critical importance of advanced imaging technologies for advancing endovascular techniques and provides practical solutions to overcome current limitations, significantly enhancing the quality of endovascular treatments.
Nononinvasive evaluation of portal-systemic shunting by glyceryl trinitrate
Authors: Slanař O , Aubrecht J , Perlík F
Published: January 2024

Portal-systemic shunting is an important circulatory abnormality in patients with liver cirrhosis. Glyceryl trinitrate (GTN) that is normally subject to first pass elimination, may exhibit higher bioavailability in these patients. This study compares the pharmacodynamic effects of GTN after peroral and sublingual administration for noninvasive assessment of shunting. Six control subjects and 15 patients with cirrhosis were studied after oral and sublingual application of 0.5 mg of GTN. Liver cirrhosis was complicated by portal hypertension in 7 of the patients and 4 patients had surgically implanted portocaval anastomosis. Digital plethysmography, which is highly sensitive and is essentially noninvasive in nature, was used to assess and compare the pharmacodynamic effects of GTN. The following values of the ratio of areas under the pharmacodynamic effects/time curve were obtained: 0.08±0.06 in healthy subjects, 0.52±0.21 in patients with uncomplicated cirrhosis, 0.99±0.34 in patients with portal hypertension and 1.24±0.43 in patients with portal-systemic shunts. We conclude that increased bioavailability of GTN reflects portal-systemic shunting and might be used providing that the pharmacodynamic data reflect both pharmacokinetic variability and the pharmacokinetic-pharmacodynamic interrelations.
Effect of liposomal muramyl tripeptide phosphatidylethanolamine and indomethacin on hematopoietic recovery in irradiated mice
Authors: Macková NO , Fedoročko P
Published: January 2024

The effects of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE/MLV, radioprotective immunomodulator; 10 mg/kg) and indomethacin (INDO, inhibitor of prostaglandin production; 2 mg/kg) on post-irradiation recovery of hematopoietic functions in mice were investigated. Two agents with distinct radioprotective mechanisms were administered alone or in combination 24 h and 3 h before exposure to 7 Gy 60Co radiation. In the post-irradiation period (3-14 days) combined pre-treatment of mice accelerated recovery of bone marrow cellularity, weight of spleen and myelopoietic and erythropoietic activity in both hematopoietic organs, compared to treatment with MTP-PE/MLV or indomethacin alone. In the peripheral blood, improved radioprotective effects of combined drug administration were found in the recovery of reticulocytes and platelet count. No further significant differences in the recovery of leukocyte count were observed in the examined groups until post-irradiation day 14. Within the first 3-6 post-irradiation days, the bone marrow and peripheral blood smears of mice pre-treated with indomethacin alone or its combination with MTP-PE/MLV more frequently featured blast cells and large cells with abundant cytoplasm which could be considered the hematopoietic stem cells.
The role of carbon dioxide in free radical reactions in organism
Authors: Veselá A , Wilhelm J
Published: January 2024

Carbon dioxide interacts both with reactive nitrogen species and reactive oxygen species. In the presence of superoxide, NO reacts to form peroxynitrite that reacts with CO2 to give nitrosoperoxycarbonate. This compound rearranges to nitrocarbonate which is prone to further reactions. In an aqueous environment, the most probable reaction is hydrolysis producing carbonate and nitrate. Thus the net effect of CO2 is scavenging of peroxynitrite and prevention of nitration and oxidative damage. However, in a nonpolar environment of membranes, nitrocarbonate undergoes other reactions leading to nitration of proteins and oxidative damage. When NO reacts with oxygen in the absence of superoxide, a nitrating species N2O3 is formed. CO2 interacts with N2O3 to produce a nitrosyl compound that, under physiological pH, is hydrolyzed to nitrous and carbonic acid. In this way, CO2 also prevents nitration reactions. CO2 protects superoxide dismutase against oxidative damage induced by hydrogen peroxide. However, in this reaction carbonate radicals are formed which can propagate the oxidative damage. It was found that hypercapnia in vivo protects against the damaging effects of ischemia or hypoxia. Several mechanisms have been suggested to explain the protective role of CO2 in vivo. The most significant appears to be stabilization of the iron-transferrin complex which prevents the involvement of iron ions in the initiation of free radical reactions.
Effects of alprazolam and fluoxetine on morphine sensitization in mice
Authors: Votava M , Kršiak M , Moravec V
Published: January 2024

Benzodiazepines seem to be frequently abused in conjunction with opioids. Fluoxetine was reported to block morphine locomotor sensitization in rats. Sensitization has been implicated in some aspects of drug abuse. We have investigated the effect of alprazolam (0.25 mg/kg) and fluoxetine (5 mg/kg) on the development and expression of sensitization to the locomotor stimulant effect of morphine (10 mg/kg) in mice. Sensitization was produced by daily injections of morphine (10 mg/kg) for 10 days. There was a clear sensitization of locomotor activity produced by morphine in photocell activity cages but co-administration of alprazolam with morphine had no effect on the degree of sensitization. Alprazolam was also without effect on the expression of the sensitized response to morphine in mice sensitized with morphine alone. Fluoxetine partly reduced both the development and expression of morphine sensitization. In conclusion, the present experiments have not yielded evidence that alprazolam may influence the development or the expression of sensitization to morphine. However, they have corroborated and extended results indicating that fluoxetine can attenuate, to a certain level, the development and expression of morphine sensitization.
Hypercapnia does not affect functional residual capacity enlargement induced by chronic hypoxia
Authors: Maxová H , Vízek M
Published: January 2024

To determine whether changes in partial pressure of CO2 participate in mechanism enlarging the lung functional residual capacity (FRC) during chronic hypoxia, we measured FRC and ventilation in rats exposed either to poikilocapnic (group H, FIO2 0.1, FICO2 <0.01) or hypercapnic (group H+CO2, FIO2 0.1, FICO2 0.04-0.05) hypoxia for the three weeks and in the controls (group C) breathing air. At the end of exposure a body plethysmograph was used to measure ventilatory parameters (V´E, fR, VT) and FRC during air breathing and acute hypoxia (10 % O2 in N2). The exposure to hypoxia for three weeks increased FRC measured during air breathing in both experimental groups (H: 3.0±0.1 ml, H+CO2: 3.1±0.2 ml, C: 1.8±0.2 ml). During the following acute hypoxia, we observed a significant increase of FRC in the controls (3.2±0.2 ml) and in both experimental groups (H: 3.5±0.2 ml, H+CO2: 3.6±0.2 ml). Because chronic hypoxia combined with chronic hypercapnia and chronic poikilocapnic hypoxia induced the same increase of FRC, we conclude that hypercapnia did not participate in the FRC enlargement during chronic hypoxia.
Possible role of matrix metalloproteinases in reconstruction of peripheral pulmonary arteries induced by hypoxia
Authors: Novotná J , Herget J
Published: January 2024

Exposure to chronic hypoxia results in hypoxic pulmonary hypertension characterized by structural remodeling of peripheral pulmonary vasculature. An important part of this remodeling is an increase of collagen turnover and deposition of newly formed collagen fibrils in the vascular walls. The activity of collagenolytic metalloproteinases in the lung tissue is notably increased in the first days of exposure to hypoxia. The increased collagenolytic activity results in the appearance of collagen cleavages, which may be implied in the triggering of mesenchymal proliferation in peripheral pulmonary arteries. We hypothesize that radical injury to pulmonary vascular walls is involved in collagenolytic metalloproteinase activation.
The relationship between the system of IGF-I and its binding proteins and microvascular reactivity in type 1 diabetes mellitus
Authors: Kršek M , Prázný M , Škrha J , Justová V , Lacinová Z , Haas T
Published: January 2024

The system of IGF-I and its binding proteins may be involved in the pathogenesis of vascular damage in Type 1 diabetes. The aim of this study was to analyze the relationship between this system and the microvascular reactivity in Type 1 diabetes as measured by laser-Doppler flowmetry. Twenty-two Type 1 diabetic patients (13 women and 9 men) with microangiopathy and fifteen healthy subjects (8 women and 7 men) were examined clinically, underwent laser-Doppler flowmetry and intima-media thickness measurements. Fasting serum levels of IGF-I, free IGF-I, IGFBPs and lipids were examined. The microvascular reactivity was impaired in Type 1 diabetic patients. Maximal perfusion during post-occlusive reactive hyperemia (PORHmax) and during thermal hyperemia (THmax) was significantly decreased in Type 1 diabetes (p<0.01). Percentage perfusion increase in both tests (PORH and TH) was lower in Type 1 diabetes mellitus (p<0.01) and the reaction after heating was slower in diabetic patients (THmax/t) (p<0.01). We did not find any significant dependence of microvascular reactivity on the parameters of IGF-I or its binding proteins. We conclude that the microvascular reactivity is impaired in Type 1 diabetes mellitus, but this impairment is not clearly dependent on the activity of the IGF-I system. It is probably only a complementary pathogenic factor.
Güvence Denetimi ve Hukuki Altyapısı
Authors: Aydoğan Gökhan , Ertugay Emrah
Published: January 2024

Şirketlerin üretmiş olduğu bilgilerin bilgi kullanıcıları için güvenilir olmasını sağlamaya yönelik hukuki araçlardan en önemlisi “denetim”dir. Denetimin farklı türleri olmakla birlikte bunlar arasında “güvence denetimi”; finansal ve finansal olmayan özel nitelikli bilgilerin tarafsız, bağımsız ve uzman kişiler tarafından bu alana ilişkin oluşturulan belirli standartlar çerçevesinde incelenip “doğrulama hizmeti” veya “doğrudan denetim” yoluyla “makul” veya “sınırlı” olmak üzere iki tür güvence düzeyine ulaşılmasına yönelik bir faaliyettir. Söz konusu faaliyet, Uluslararası Muhasebeciler Federasyonu bünyesindeki Uluslararası Bağımsız Denetim ve Güvence Denetimi Standartları Kurulu tarafından hazırlanan ve Türkiye de dâhil birçok ülkede model olarak kullanılarak yürürlüğe konulan belirli standartların kapsadığı konularda yürütülebilmektedir. Türkiye’de özellikle son dönemde daha da önem kazanmış olan konkordato süreçleri, sürdürülebilirlik raporlamaları ve sermaye piyasası araçlarının halka arzı için hazırlanan izahnamelerde yer alan birtakım bilgiler hakkında güvence denetiminin gerçekleştirilmesi bu konuda yürürlüğe konulan standartları önemli kılmaktadır.
Bu çalışmada güvence denetiminin kavramsal çerçevesi ve terminolojisi, hukuki altyapısı, yürürlükte olan güvence denetimi standartları ve güvence denetiminin Türkiye’deki kullanım alanları ele alınmıştır. Aynı zamanda bu faaliyetin yürütülmesine temel teşkil eden güvence denetimi sözleşmesi; sözleşmenin tarafları, şekli ve hukuki niteliği bağlamında incelenmiştir
Analysis of Employee Competency Development
Authors: Setiawan Irfan
Published: January 2024

AThis research aims to examine the analysis of the competency development of the State Civil Officials in Tangerang Regency. This study uses a descriptive qualitative research method with an inductive approach. Primary data collection comes from observations and interviews with informants, namely employees who have the authority and duties in developing the competence of Officialsin Tangerang Regency, and Secondary Data obtained from documents at the Tangerang Regency Personnel and Human Resources Development Agency. Researchers used the data analysis technique of the Miles & Huberman model. Competency development carried out by the Tangerang Regency Personnel and Human Resource Development Agency has not been running effectively due to a lack of cooperation built by the Tangerang Regency Personnel and Human Resource Development Agency, the implementation of the Training Needs Analysis has not been maximized, the ineffectiveness of the implementation of education and training, there is still political intervention in the implementation of transfer, as well as the lack of motivation for civil servants in Tangerang Regency. So that the Personnel and Human Resources Development Agency for Tangerang Regency needs to build cooperation by conducting information dissemination and field visits related to the conditions for developing civil servant competencies, maximizing the SIMPEG and SIDAK applications to streamline the implementation of Training Needs Analysis, increasing supervision in organizing training and carrying out transfer management based on the principle put the right people in the right places.
The Implementation of Talent Management Implementation at Regional Employee Agency Wonogiri Regency Central Java
Authors: Ambarawati Ni Gusti Made Ayu , Wijoyo Risang Priyo
Published: January 2024

Bureaucratic Reform (RB) in Indonesia represents a strategic redesign of the bureaucratic system to adapt to societal and global dynamics. Within the spectrum of RB-induced changes, particular attention is given to human resources, with Talent Management emerging as a pivotal element aimed at enhancing the governance of civil servants (ASN). This research seeks to explore the implementation of Talent Management in the Regional Employee Agency (BKD) of Wonogiri Regency, examining both supporting and inhibiting factors, and proposing solutions in line with Policy Implementation theory. Employing qualitative research methods encompassing observation, interviews, and documentation, the study reveals that the implementation of Talent Management in Wonogiri Regency is generally commendable, driven by effective communication, the commitment of the Wonogiri Regent, and clear Standard Operating Procedures (SOPs). Nevertheless, challenges include the absence of assessors, lack of an Assessment Center, insufficient budget allocation, and the absence of a dedicated field for Talent Management. Mitigation efforts involve certifying assessor employees, proposing the construction of an Assessment Center, requesting budget allocations, and refining the organizational structure to address these challenges and further enhance the Talent Management framework.
Queerlit – a bibliography of Swedish fiction with LGBTQI topics
Authors: Humlesjö Siska , Bergenmar Jenny , Matsson Arild
Published: January 2024

This paper summarizes the project Queerlit: Metadata and Searchability for LGBTQ+ Literary Heritage 2020-2023 and discusses some challenges in the development of this resource. The Queerlit project consist of four parts: 1. Creating a bibliography of Swedish fiction with LGBTQI themes 2. Creating a Swedish thesaurus (QLIT), adapted from the of the linked open data thesaurus Homosaurus 3. Assigning all material in the bibliography with subject headings from QLIT. 4. A web user interface for searching the material All four parts are integrated with the Swedish union catalog, Libris, making the results of the project available for all under a CC0 license. QLIT is the first external thesaurus integrated in the linked open data framework used in the technical platform of Libris, XL. The bibliography spans from rune stones from the 7th century to recently published fiction. When applying subject headings for the material both general aspects of the work and specific LGBTQI topics are described, making this the most comprehensive retrospective indexing project of Swedish literature to date. The underlying knowledge organization is made a prominent method of interacting with the search interface, which is empirically designed around the needs of various user groups.
Research stories on Twitter
Authors: Lorentzen David G. , Nelhans Gustaf
Published: January 2024

This paper aims to study what type of research seems to interest the users of a social network platform and then complement the data with data from an open catalogue for research, exemplifying with Twitter and Open Alex. The basic idea is to get an overview of the stories the platform content tells during three months regarding topics, disciplines, and open access status. The findings suggest that the picture look very different between the approaches to map the topics, especially when looking at the articles most mentioned compared to the ones that are most retweeted. The study mainly highlights the methodological opportunities of combining text analysis and link relationships to explore the content and public interest in academic research.
Humanistic AI: Towards a new field of interdisciplinary expertise and research
Authors: Fridlund Mats , Alfter David , Brodén Daniel , Green Ashely , Karimi Aram , Lindhé Cecilia
Published: January 2024

The Gothenburg Research Infrastructure in Digital Humanities (GRIDH) have participated in projects within various humanities fields that utilise as well as develop research tools and infrastructural resources that incorporate applications of ‘artificial intelligence’ (AI). These applications can include natural language processing, machine learning, computer vision, large language models, image recognition algorithms, classification, clustering, and deep learning. This paper advances the term ‘humanistic AI’ to describe an emergent form of interdisciplinary practice that uses and develops AI-based research applications to answer humanities research questions together with its entangled humanistic reflection. We coin this term to make implicit and visible the epistemological and material particularities of its practice and the new forms of knowledge its affordances make possible. The paper presents GRIDH projects within ‘humanistic AI’ together with its developed AI resources and applications.
Samförfattande som datadriven tvärvetenskap: Pragmatiska lärdomar från SweTerror-projektet
Authors: Brodén Daniel , Fridlund Mats , Olsson Leif-Jöran , Ängsal Magnus P. , Öhberg Patrik
Published: January 2024

Terrorism i svensk politik (SweTerror) är ett storskaligt tvärvetenskapligt forskningsprojekt med forskare från såväl human- och samhällsvetenskaperna som datavetenskaperna. Samtidigt använder och utvecklar SweTerror nationell forskningsinfrastruktur för riksdagsdata. Detta paper beskriver användningen av samförfattande som en datadriven tvärvetenskaplig praktik för att integrera olika vetenskapliga perspektiv och skapa samsyn i projektforskningen. Vi tar fasta på betydelsen av valet att koncentrera samarbetsformen kring konferenspapers inom specifikt digital humaniora och diskuterar erfarenheten av att samskrivande försvagar vetenskapligt revirtänkande, liksom ett iterativt förhållningssätt till forskningsdata kopplade till forskningsinfrastrukturer under uppbyggnad. Avslutningsvis betonar vi datadrivet samförfattande som en pragmatisk praktik för att stärka kollaborativt samarbete och kunskapsbryggor inom en tvärvetenskaplig forskargrupp.
Acessing centuries of documentation - Resources to improve access to Swedish rock art documentation and metadata
Authors: Green Ashely , Bridge Tristan , Horn Christian , Humlesjö Siska , Karimi Aram , Ling Johan , Westin Jonathan
Published: January 2024

The archive of rock art documentation maintained by SHFA provides a valuable resource to archaeologists and others who study rock art. The archive includes images of rock art documentation, sites, and the documentation process, from the 17th century to the more recent high resolution 3D recording and visualizations. In the last few years, GRIDH, in collaboration with SHFA, have begun to improve access to the archive through a Django-based solution and new digital resources. In this paper, we introduce the images in the archive, provide details on the new digital resources, and reflect on how the new website will impact data availability and rock art research.
Kosten att bedriva svensk ordforskning utan att kränka upphovsrätten
Authors: Bouma Gerlof , Forsberg Markus , Sikora Justyna , Sköldberg Emma
Published: January 2024

Vi beskriver KB-labb och Språkbanken Texts samarbete för att underlätta ordforskning på de upphovsrätts-skyddade korpusar som finns i Kungliga bibliotekets samlingar. Satsningen har hittils lett till två öppna datasamlingar, Kubord 1 och 2, som ger tillgång till ordstatistik och ordsamförekomststatistik. Vi beskriver även Kubord-fastText, en samling vektormodeller som är baserade på samma korpusar, som är under utveckling.
Efforts of Government Institutions to Support Exclusive Breastfeeding Among Civil Servants
Authors: Batjo Siti Hadijah , Hadiha Hadina , Muliani Muliani , Radjulaini Zakiah
Published: January 2024

Exclusive breastfeeding rate in Palu City has decreased in the last three years from 59.9% (2018) to 57.8% (2019) and 52.42% (2020). Work caused failure to provide exclusive breastfeeding among women. This study aims to explore the efforts of government institutions to support exclusive breastfeeding among civil servants in Palu City, Central Sulawesi. This study applied a qualitative approach, constructivism paradigm, and phenomenological strategy. The study subjects were selected according to the study objectives, which involved the main informants namely the heads of health department; women's empowerment and child protection department, education department, employment department, social affairs department and head of the Religious Office. In addition, there were key informants, namely civil servants with babies aged <12 months who had breastfed or were currently breastfeeding. The number of study subjects was considered sufficient when the coding results and data categories obtained were saturated. Triangulation was carried out towards the Mayor of Palu. Data were collected through in-depth interviews based on interview guides. All interviews were recorded using an audio recorder. The main instrument in this study was the researchers. Ethical Clearance letter Number: 0042/KEPK-KPK/V/2022 dated June 7, 2022 was issued by the Ethics Commission of Palu Health Polytechnic. The results revealed that breastfeeding rooms in the workplace were not yet available for breastfeeding women; there was no reduction in working hours for breastfeeding women, the workload for breastfeeding women was the same, and there was no specific support or motivation from the leaders, and no one had ever provided rewards. Furthermore, the triangulation towards the Mayor of Palu revealed that he promised to make a Regional Regulation (PERDA) that women who exclusively breastfeed will be given leave for 6 months. It can be concluded that the government institutions had not provided support for civil servants to perform exclusive breastfeeding. To achieve the target of exclusive breastfeeding, the government must support exclusive breastfeeding.
Exploring Spiritual-Based Transformational Leadership Indicators in Palu City Hospital: A Qualitative Study
Authors: Kolomboy Fajrillah , Rizkaningsih Rizkaningsih , Syamsu Andi Fatmawati
Published: January 2024

Due to contextual issues, including social culture and pluralism, spiritual-based leadership in the nursing field has rarely received attention, resulting in comparatively few research projects. Whereas such research can lead to a spiritually supportive environment, benefiting the patients, nurses, and organizations. Current research aims to explore indicators of spiritual-based transformational leadership in Palu City Hospital. This research was done qualitatively through a grounded theory approach and Focus Group Discussion (FGD). In this case, 12 informants were chosen by purposive sampling. The instrument used was Focus Group Discussion (FGD) guidelines. In this study, the results of the FGD were analyzed using the N Vivo 12 Plus. Based on the qualitative data analysis results, a spiritual-based transformational leadership required three primary skill indicators, namely emotional skills, including emotional proficiency and emotional intelligence, spiritual skills including spiritual attitudes and spiritual intelligence, and social skills, namely being able to behave socially. For further research, it is necessary to carry out model intervention and model evaluation under new normal conditions and add other variable components such as performance and commitment.
Healthy Food Education Affects Underweight Adolescent's Knowledge and Intakes of Energy, Macro and Micro Nutrients
Authors: Mustafa Annasari , -Sutjiati Endang , Agustin Sheily Inge
Published: January 2024

One of the causes of underweight is an imbalance between nutritional intake and needs. The condition often occurs in teenagers and in Indonesia there are 8.1%. This study aims to investigate the impact of healthy diet education delivered by peers on the level of knowledge; energy, macro and micro nutrients intake among underweight adolescents at state Senior High School 1 in Singosari, Malang Regency. This study conducted on 33 undeweight adolescent’s girls selected based on inclusion criteria. Data collection was carried out before and after the intervention. Adolescents’ nutritional knowledge was collected by asking questions using Google forms and food consumption data collection was carried out by direct interviews using a 24-hour food recall form. The intervention took the form of education and guidance from peer tutors when the subjects consumed snacks and lunch at school, which was carried out 14 times, 2 times a week during 8 weeks. The effect of providing education on the level of knowledge; Energy, carbohydrate, protein, fat and zinc intake were analyzed using the paired sample t test, while vitamin C and iron intake used the Wilcoxon test (95% CI; α = 0.05).The results showed significant improvements in the level of knowledge intake of Energy, Protein, Fat, Carbohydrates as well as Iron and Zinc (p-value <0.05), while the increase in vitamin C intake was not significantly different (p-value >0.05). These findings demonstrated the potential of providing healthy diet education by peers to increase knowledge, energy, macro and micro nutrient intake among underweight adolescent girls.
Related Factors, Causes and Stress Respons of Hypertension Patients in Coastal Communities: Mixed Method
Authors: Atoy Lena , Tahir Rusna , Rini Dewi Sartiya , Pertami Sumirah Budi
Published: January 2024

Hypertension is a non-communicable disease (NCD) that is now a health problem that is difficult to control in number and is the cause of high mortality and morbidity rates globally. In addition to the prevalence of events that are increasing over time, hypertension is also known to be dangerous because it is a risk for other chronic diseases such as heart disease and stoke disease. This study aims to analyze the incidence and related factors of hypertension in coastal communities in Motui District, North Konawe Regency, Southeast Sulawesi Province. The research design uses a mix of quantitative and qualitative methods. Quantitative methods use cross-sectional while quantitative methods by determining themes. The sample in the study was 60 people with hypertension. Sampling technique with non probability sampling with consecutive sampling method. The results showed that 44 people (73.3%) experienced severe stress and 16 people (26.7%) experienced moderate stress. Some factors that cause stressful events are gender (p = 0.002), and occupation (p = 0.000). The cause of stress experienced is due to the heavy workload, economic difficulties and personal problems. While the response of hypertension patients who experience stress is anger, anxiety and pressure and crying. The conclusion of this study is that people with hypertension experience severe stress caused by workload, economic and personal problems.
Combination of Eucheuma Cottonii and Corticosteroids has a Superior Immunomodulatory Effect on Asthma
Authors: Rizaldy Rheza , Mulyani Sri Priantini , Sumarawati Titiek
Published: January 2024

Asthma prevalence has been increasing globally which is commonly treated using corticosteroid as gold standard treatment. However, corticosteroids have adverse effects and cases of corticosteroid-resistant asthma are emerging. Eucheuma cottonii (EC) has been shown to potentially attenuate inflammatory response in type I hypersensitivity. This study aimed to investigate the effect of Eucheuma cottonii extract and methylprednisolone combination on IL-4, IL-10, and histamine levels in Ovalbumin-induced asthma BALB/c mice. Thirty female BALB/c mice were randomly assigned to 6 groups : (1) Sham; (2) Ovalbumin-induced asthma mice; (3) Ovalbumin-induced asthma mice treated with methylprednisolone (MP) 0.24 mg/day; (4) Ovalbumin-induced asthma mice treated with EC extract 300 mg/kgBW/day; (5) Ovalbumin-induced asthma mice treated with combination of both. Treatments were given respectively for 7 days. Plasma IL-4, IL-10, and histamine levels were measured using ELISA method. The combination group showed both the lowest IL-4 levels (89.30 ± 1.37 pg/ml) and  the highest IL-10 levels (487.03 ± 20.57 pg/ml) compared to other asthma-like mouse groups (p = 0.001). No significant difference was observed in histamine levels among all treatments (p > 0.05). The administration of a combination of methylprednisolone and Eucheuma cottonii extract significantly affected plasma IL-4 and IL-10 levels compared to monotherapies. However, there was no significant difference in plasma histamine levels compared to monotherapies.
Spiritual Emotional Freedom Technique Intervention on Anxiety Level of Hypertensive Heart Disease Patients
Authors: Rachman Wa Ode Nova Noviyanti , Rahmadhania Wa Ode , Indriani Cece , Yani Ahmad , Ima Lukman
Published: January 2024

Hypertension is one of the leading causes of various heart diseases. In patients with Hypertensive Heart Disease (HHD), anxiety symptoms can continue to increase, which can affect the treatment and healing process and can cause various complications. This study aims to determine the effect of Spiritual Emotional Freedom Technique (SEFT) therapy on anxiety levels in HHD patients in the ICCU room of Kendari City Hospital. This type of research is a pre-experiment with a one-group pretest-posttest design. The population in this study were all HHD patients treated in the ICCU room of Kendari City Hospital. The sampling technique used was purposive sampling, with a total sample size of 22 respondents. This research instrument uses the Anxiety Visual Analog Scale (VAS-A) questionnaire sheet to measure anxiety levels. The analysis method uses a paired-sample t-test. The results showed that the level of anxiety before and after SEFT therapy decreased. This can be seen from the statistical test p-value = 0.000 < α = 0.05, which shows a significant difference. It can be concluded that SEFT therapy influences reducing anxiety levels in HHD patients. It is expected for service institutions and other institutions to provide training for health workers to perform SEFT therapy to help reduce patient anxiety levels.
Pembagian Masker Kepada Masyarakat Sebagai Upaya Pencegahan Penyebaran Covid-19
Authors: Gustini Gustini , Wartana I Kadek , Elmiyanti Ni Ketut
Published: January 2024

Coronavirus Disease 2019 (COVID-19) merupakan penyakit menular yang disebabkan oleh Coronavirus jenis baru yang menyebabkan terjadinya wabah di tengah masyarakat. Penanganan dan pencegahan kasus pandemik ini sudah dilakukan   dengan berbagai cara,  baik  secara  global  maupun nasional atau wilayah akan tetapi penerapan protokol kesehatan seperti penggunaan masker oleh masyarakat  dalam pencegahan terinfeksi Covid-19 belum berjalan secara maksimal. Penggunaan Masker sangat penting untuk melindungi pemakainya dari berbagai infeksi atau kemungkinan menularkan infeksi Covid-19. Melihat masih banyaknya masyarakat yang belum menggunakan masker saat berada di tempat umum, maka dosen bersama mahasiswa STIK Indonesia Jaya melakukan kegiatan pengabdian kepada masyarakat melalui pembagian masker untuk mencegah terjadinya penularan Covid-19 di Desa Binangga Kecamatan Marawola Kabupaten Sigi. Kegiatan pembagian masker ini dilakukan pada saat berlangsungnya kegiatan lomba karapan sapi, mengingat banyaknya masyarakat yang mengikuti kegiatan tersebut tetapi tidak menggunakan masker. Hal ini dilakukan secara langsung dengan membagikan masker kepada masyarakat terutama masyarakat yang tidak memiliki dan tidak menggunakan masker di tempat berlangsungnya lomba karapan sapi di Desa Binangga. Kegiatan Pembagian masker dilakukan pada tanggal 22 Maret 2021 kepada 100 orang masyarakat yang tidak memiliki/menggunakan masker. Masyarakat yang diberikan masker menggunakan masker dengan tepat terutama di tempat umum pada saat kegiatan perlombaan karapan sapi berlangsung.
Peningkatan Kesejahteraan Penderita Diabetes Melitus melalui Edukasi dan Simulasi Senam Kaki Diabetik
Authors: Semuel Ra’bung Alfrida , Gustini  , Salamung Niswa
Published: January 2024

Diabetes melitus merupakan penyakit kronik berupa gangguan metabolisme yang dipengaruhi oleh gaya hidup dan pola makan. Salah satu komplikasi yang paling umum terjadi pada pasien DM yaitu  kaki diabetik yang diakibatkan oleh aliran darah pada bagian ekstremitas bawah tidak lancar. Komplikasi ulkus diabetik dapat meningkatkan rawat inap pasien diabetes, meningkatkan beban ekonomi keluarga dan menyebabkan peningkatan morbiditas dan mortalitas. Salah satu upaya yang dapat dilakukan untuk mencegah terjadinya komplikasi bisa dilakukan dengan latihan jasmani berupa senam kaki diabetik. Berdasarakan data yang diperoleh di Posyandu Aster belum pernah dilakukam penyuluhan dan senam kaki diabetik. Adapun tujuan pengabdian masyarakat ini yaitu untuk menambah pengetahuan dan meningkatkan kesadaran penderita DM dalam mencegah terjadinya komplikasi neuropati. PkM ini dilaksanakan di Posyandu Aster Puskesmas Sangurara pada tanggal 15 Januari 2020. Khalayak sasaran dalam kegiatan ini yaitu penderita diabetes yang berjumlah 20 orang. Metode PkM ini yaitu pemberian edukasi dan simulasi senam kaki diabetik. Hasil PkM ini diperoleh sebagian besar peserta dapat menyebutkan pengertian, tujuan, dan manfaat senam kaki diabetik dan semua peserta dapat mempraktekkan senam diabetk dengan baik. Kegiatan senam kaki ini dapat dijadikan salah satu program diwilayah tersebut dalam rangka meningkatkan kesehatan dan mencegah terjadinya komplikasi DM sehingga kesejahteraan pasien DM meningkat.
Mewujudkan Masyarakat Desa Sehat Melalui Penyuluhan Perilaku Hidup Bersih dan Sehat
Authors: Mangemba Daeng , Musaidah  , Normalia
Published: January 2024

Perilaku Hidup bersih dan sehat (PHBS) adalah upaya yang harus dilakukan untuk mewujudkan masyarakat desa yang sehat. PHBS adalah sebuah rekayasa sosial yang bertujuan menjadikan sebanyak mungkin anggota masyarakat sebagai agen perubahan agar mampu meningkatkan kualitas perilaku sehari – hari dengan tujuan hidup bersih dan sehat. Langkah ini harus diawali dari perubahan pola pikir sehat masyarakat yang harus diusahakan oleh diri sendiri. Upaya ini adalah untuk mewujudkan masyarakat desa sehat sebagai satu modal utama bagi pembangunan sumber daya manusia yang produktif. Sementara itu, kesadaran masyarakat akan kesehatan dan pola hidup bersih sehat, khususnya masyarakat dusun berua desa kale bentang masih rendah. Untuk itu pelaksanaan penyuluhan Perilaku Hidup bersih sehat bertujuan untuk meningkatkan kesadaran masyarakat akan pentingnya menerapkan Perilaku Hidup bersih sehat dalam kehidupan sehari-hari sehingga dapat terwujud masyarakat desa sehat. Kegiatan ini dilakukan dengan pemberian edukasi berupa penyuluhan terkait perilaku hidup bersih sehat kepad masyarakat desa. Adapun hasil yang diperoleh, yaitu terjadinya peningkatan pemahaman masyarakat desa mengenai perilaku hidup bersih dan sehat. kegiatan seperti ini sangat penting dilakukan secara berkelanjutan terutama pada masyarakat pedesaan untuk menyadarkan pentingnya melaksanakan Perilaku Hidup bersih dan sehat..
Peningkatan Pengetahuan Pasien Katarak Melalui Edukasi Pemberian Obat Tetes
Authors: Gustini Gustini , Wartana I Kadek
Published: January 2024

Katarak merupakan kelainan mata yang umum terjadi. Katarak terjadi karena proses penuaan alami pada lensa mata. Oleh karena itu, risiko katarak akan meningkat seiring dengan bertambahnya usia. Faktor risiko katarak antara lain mencakup miopia yang serius, paparan sinar matahari yang terlalu lama, penyakit tertentu seperti diabetes, atau penggunaan obat-obat tertentu. Katarak awal tidak memiliki gejala yang jelas. Jika tidak diobati, katarak bisa menyebabkan kebutaan yang permanen. Pencegahan yang dilakukan supaya tidak terjadi kebutaan yang permanen adalah melakukan operasi katarak. Berdasarkan data yang diperoleh di Rumah Sakit Umum Daerah Palu belum pernah dilakukan penyuluhan tentang perawatan mata pada pasien post op katarak. Adapun tujuan pengabdian kepada masyarakat ini untuk menambah pengetahuan pasien post op tentang perawatan mata. Kegiatan ini dilaksanakan pada 05 Mei 2021. Khalayak sasaran dalam kegiatan ini yaitu pasien post op katarak dan keluarga sebanyak 20 orang. Metode pengabdian yaitu memberikan edukasi peningkatan pengetahuan pasien post op katarak tentang perawatan mata. Hasil kegiatan ini diperoleh sebagian besar peserta dapat menyebutkan pengertian dari katarak, penyebab katarak, tanda dan gejala katarak serta cara perawatan mata post op katarak.. Kegiatan penyuluhan ini dapat dijadikan salah satu program di ruangan Aster RSUD Undata dalam rangka meningkatkan pengetahuan dan pencegahan terjadinya komplikasi sehingga penyembuhan mata pada pasien lebih cepat.
Pelatihan Senam Kaki Diabetik Bagi Pasien Diabetes Melitus di Wilayah Kerja Puskesmas Pembantu Tondo
Authors: Saleh Azizah , Nurmalisa Baiq Emy , Kolomboy Fajrillah
Published: January 2024

Persentase diabetes mellitus (DM) tertinggi pada tahun 2016 adalah Kota Palu sebesar 0,45%. Neuropati diabetik yang menjadi komplikasi paling sering pada pasien diabetes melitus ini menjadi penyebab tingginya angka morbiditas pada pasien diabetes melitus dan bahkan menyebabkan  amputasi. Senam kaki diabetes digunakan sebagai latihan kaki dan bermanfaat dalam mengurangi nyeri, mengurangi kerusakan saraf dan mengontrol gula darah serta meningkatkan sirkulasi darah pada kaki. Tujuan pengabdian masyarakat ini  adalah meningkatkan pengetahuan dan kemampuan pasien Diabetes Melitus dalam melakukan senam kaki diabetik. Metode yang digunakan dalam kegiatan  ini adalah penggabungan metode ceramah, diskusi, demonstrasi dan praktek. Media yang digunakan untuk membantu penyampaian materi adalah leaflet. Kegiatan diawali dengan tahap persiapan, pelaksanaan dan evaluasi. Untuk mengetahui efektifitas kegiatan ini maka dilakukan apersepsi untuk mengukur sejauhmana tingkat pengetahuan peserta dan diakhir kegiatan dilakukan evaluasi dengan memberikan pertanyaan terkait materi yang sudah disampaikan serta peserta diminta untuk redemonstrasi senam kaki DM . Tingkat keberhasilan pelaksanaan pengabdian masyarakat ini dapat dilihat dari ketercapaian jumlah peserta, tujuan dan target materi. Jumlah peserta yang hadir sebanyak 28 peserta.  Tujuan pengabdian tercapai dilihat dari antusias para peserta dan di akhir kegiatan peserta bisa menjawab pertanyaan yang diajukan oleh tim pengabdi dan dapat melakukan redemonstrasi senam kaki DM. Diharapkan bagi Puskesmas Talise untuk melaksanakan kegiatan serupa secara berkala dan jumlah peserta yang lebih besar agar semua pasien DM yang ada di wilayah kerja Puskesmas Talise memiliki pengetahuan dan keterampilan yang baik dalam melakukan senam kaki
Sosialisasi dan Simulasi Tindakan Basic Life Support (BLS) pada Masyarakat di Lingkungan Pelabuhan Taipa
Authors: Supirno Supirno , Jurana Jurana , Amir Amir
Published: January 2024

Introduction Emergency situations can occur at any time and anywhere, and happen to anyone. Efforts to reduce the number and severity of victims require appropriate knowledge by rescuers. Increased readiness can be carried out through outreach and simulations of how to help victims through Basic Life Support (BLS)/basic life assistance. The purpose of community service is to increase community capacity in providing basic life support to victims. Methods of outreach and simulation to the general public. The target participants were Taipa port workers and the community as many as 35 people. Palu Ministry of Health Polytechnic as initiator and facilitator, as well as funding source. The activity begins with participant identification, participant approval, pre-test, then training (socialization and simulation) is held, guidance/assistance and ends with a post-test to determine changes in participants' abilities. Results: the activity was carried out on 15-16 February 2023 at Taipa Port attended by 35 participants consisting of Taipa Port officials, representatives from Sub-District and Community Officials. All participants participated from the beginning to the end of the activity, both during the delivery of material, discussions and during practice using the BHD pantom. Judging from the pre-test scores with an average score of 88.85 and an average score of 96.6, there was an increase in participants' knowledge. The conclusion is that there needs to be continuity of BHD training activities periodically and for communities with more targets.
Aktifitas fisik berupa Senam Lansia pada Masa New Normal
Authors: Siregar Hasbunsyah , Baiq Emy Nurmalisa
Published: January 2024

Introduction: The new normal period requires people to implement health protocols including social distancing which requires staying at home. This causes a decrease in community activity, including the elderly, who are a vulnerable group in the transmission of Covid-19. On the other hand, a decrease in the activity of the elderly can lead to reduced immunity and the health of the elderly in general. The aim of this community service is to increase the motivation of elderly people to do elderly exercise by implementing health protocols. Method This community service activity was carried out on June 10 2022. The targets involved in this community service activity were all elderly people and PSTW Tentena Madago administrators. Health promotion in the form of counseling and direct practice of exercise for the elderly is the method used to carry out this community service. Counseling material was carried out before the exercise by emphasizing the importance of physical activity for the elderly during the new normal period as an effort to increase the immunity of the elderly. The results of educational activities and elderly exercise can increase the motivation of elderly people to get involved in elderly exercise at PSTW Madago. Physical activity in the form of exercise for the elderly needs to be routine as an effort to maintain the health of the elderly at PSTW Madago
Pengaruh Terapi Bermain terhadap Kecemasan Anak Usia Sekolah Saat Hospitalisasi di Ruangan Catelia Rumah Sakit Umum Daerah Undata Palu
Authors: Mangundap Selvi Alfrida
Published: January 2024

Hospitalisasi adalah keadaan yang menyebabkan seseorang harus tinggal dirumah sakit untuk mendapatkan perawatan dan pengobatan. Salah satu akibat anak yang mengalami hospitalisasi adalah kecemasan. Kecemasan yaitu suatu respon emosional terhadap penilaian sesuatu yang dianggap membahayakan, dimana cemas sangat berkaitan dangan perasaan ketidakpastian dan ketidakberdayaan. Salah satu intervensi keperawatan anak untuk membantu mengurangi kecemasan anak sekolah selama menjalani hospitalisasi adalah terapi bermain. Tujuan penelitian ini adalah diketahuinya pengaruh terapi bermain terhadap kecemasan anak usia sekolah saat hospitalisasi di ruangan Catelia Rumah Sakit Umum Daerah Undata Palu Tahun 2017. Desain penelitian ini adalah penelitian kuantitatif dengan rancangan quasi eksperiment dengan one group pre test and post test design. Pada penelitian ini responden diberikan perlakuan bermain menggunakan model permainan bola kaki mini yang dirancang sendiri, proses pengambilan data dilakukan sebelum dan sesudah bermain. Hasil menunjukkan bahwa terdapat berbedaan yang signifikan antara kecemasan sebelum diberikan terapi bermain dan sesudah dilakukan terapi bermain pada anak usia sekolah saat hospitalisasi di ruangan Catelia Rumah Sakit Umum Daerah Undata Palu. Kesimpulan dalam penelitian ini adalah terdapat berbedaan yang signifikan antara kecemasan anak usia sekolah sebelum dan sesudah bermain. Saran, perawat perlu memberikan terapi bermain sebagai salah satu paket dalam merawat pasien anak karena merupakan bagian dari tindakan mandirinya.