bluuebunny/crossref_metadata_2025 huggingface dataset:
The Right to Vote in the Light of an Individual’s End of Life
Authors:   Uniwersytet Szczeciński, Zych Radosław
Published: February 2024

This paper has the following research thesis: An individual’s end of life has far-reaching legal effects, also in the sphere of the person’s subjective rights. The research problem consists in reflecting on the right to vote, understood as a human right, in the light of a set of legal norms that undergo changes quite frequently. The aim of this paper is to examine what concepts the legislator uses to describe the death of a person and what effects it brings in the sphere of substantive law? Does the current legal state require amendments? If so, what kind of changes? To determine this, I will examine two fundamental normative acts in the Polish system of sources of law: the Constitution and the Electoral Code. In the research conducted, I will apply the formal-dogmatic method. Apart from legal regulations, I will examine the opinions of legal scientists and some relevant judicial decisions. The Constitution does not link the consequences in the sphere of the electoral law to the end of individual’s life. Electoral Code uses the terms “death” and “died” directly providing for the end of life in special situations confirming the natural consequence of a given state of affairs and requiring various procedural steps. The author expresses the hope that his findings will become the basis for further profound research on the issues of electoral procedures related to the death of a person as: a voter, candidate or member of electoral bodies.
Wpływ francuskiego Trybunału Konstytucyjnego na krajowy system podatkowy. Analiza na przykładzie podatku od bardzo wysokich dochodów (taxe sur les très hauts revenus)
Authors:   Uniwersytet w Białymstoku, Popławski Mariusz , Pahl Bogumił ,   Uniwersytet Warmińsko-Mazurski w Olsztynie, Mariański Michał ,   Uniwersytet Warmińsko-Mazurski w Olsztynie
Published: February 2024

This publication is a part of the study of the role of French Constitutional Court (Conseil constitutionnel) in the field of control of tax law regulations. The main purpose of this publication is not only to describe the specificity of the French legal system in this field but in the basis of the functional approach of the comparative legal method, the historical-descriptive and the dogmatic method, the verification of the thesis of the effectiveness of constitutional control of tax regulations in French legal system. This study that was done on the example of the high income tax (fr. taxe sur les très hauts revenus) however, it may be an incentive for further in-depth research in this area.
Wojciech Bogumił Jastrzębowski’s Draft European Constitution Versus the Contemporary Realisation of the Idea of Continental Unity
Authors:   Nicolaus Copernicus University in Toruń, Serowaniec Maciej , Gaca Andrzej ,   Nicolaus Copernicus University in Toruń
Published: February 2024

Wojciech Bogumił Jastrzębowski’s draft of a Constitution for Europe is a vision of an ideal European social order, whose foundation is to be found, inter alia, in the citizen’s universal right to freedom and independence, to diversity and individual identity, as well as the right to live in peace. It is thus highly apparent that a number of parallels exist between the alliance of nations postulated by Jastrzębowski and later forms of integration existing and still being developed in contemporary Europe. The aim of this article is to analyse and characterize the existing similarities, and also the most significant differences, between the monarchist vision of the European alliance of nations, as presented by the author of the Constitution for Europe, and the contemporary realisation of the idea of the unity of the continent.
The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function
Authors: Haykir Betül , Moser Seraina Olivia , Pastor-Arroyo Eva Maria , Schnitzbauer Udo , Radvanyi Zsuzsa , Prucker Isabel , Qiu Danye , Fiedler Dorothea , Saiardi Adolfo , Jessen Henning J. , Hernando Nati , Wagner Carsten A.
Published: February 2024

Significance Statement

Kidneys are gatekeepers of systemic inorganic phosphate balance because they control urinary phosphate excretion. In yeast and plants, inositol hexakisphosphate kinases (IP6Ks) are central to regulate phosphate metabolism, whereas their role in mammalian phosphate homeostasis is mostly unknown. We demonstrate in a renal cell line and in mice that Ip6k1 and Ip6k2 are critical for normal expression and function of the major renal Na+/Pi transporters NaPi-IIa and NaPi-IIc. Moreover, Ip6k1/2

−/−
mice also show symptoms of more generalized kidney dysfunction. Thus, our results suggest that IP6Ks are essential for phosphate metabolism and proper kidney function in mammals.

Background

Inorganic phosphate is an essential mineral, and its plasma levels are tightly regulated. In mammals, kidneys are critical for maintaining phosphate homeostasis through mechanisms that ultimately regulate the expression of the Na+/Pi cotransporters NaPi-IIa and NaPi-IIc in proximal tubules. Inositol pyrophosphate 5-IP7, generated by IP6Ks, is a main regulator of phosphate metabolism in yeast and plants. IP6Ks are conserved in mammals, but their role in phosphate metabolism in vivo remains unexplored.

Methods

We used in vitro (opossum kidney cells) and in vivo (renal tubular-specific Ip6k1/2

−/−
mice) models to analyze the role of IP6K1/2 in phosphate homeostasis in mammals.

Results

In both systems, Ip6k1 and Ip6k2 are responsible for synthesis of 5-IP7. Depletion of Ip6k1/2 in vitro reduced phosphate transport and mRNA expression of Na+/Pi cotransporters, and it blunts phosphate transport adaptation to changes in ambient phosphate. Renal ablation of both kinases in mice also downregulates the expression of NaPi-IIa and NaPi-IIc and lowered the uptake of phosphate into proximal renal brush border membranes. In addition, the absence of Ip6k1 and Ip6k2 reduced the plasma concentration of fibroblast growth factor 23 and increased bone resorption, despite of which homozygous males develop hypophosphatemia. Ip6k1/2

−/−
mice also show increased diuresis, albuminuria, and hypercalciuria, although the morphology of glomeruli and proximal brush border membrane seemed unaffected.

Conclusions

Depletion of renal Ip6k1/2 in mice not only altered phosphate homeostasis but also dysregulated other kidney functions.
METHODS OF MOTIVATING STUDENTS IN THE CLASS OF KYRGYZ LITERATURE AND USING THE ELEMENTS OF ETHNOPEDAGOGY IN TEACHING STORIES
Authors:   Ministry of Education and Science of Kyrgyz Republic, Akmatov Kyalbek , Zailova Zhumagul ,   Osh State Pedagogical University, Abdibaliev Emilbek ,   Osh State Pedagogical University, Jumabaev Ertoshtuk ,   Osh State Pedagogical University
Published: February 2024

The article shows several ways to inspire students in a Kyrgyz literature lesson, and what the teacher’s activities should be. Getting students interested in a lesson is not a difficult task. The main problem is insufficient knowledge of methods and technologies for active student participation in the classroom or the inability to implement them. First of all, it is necessary to have information about the methods that interest students. Then, through experience, the deficiencies are made up for. It was noted what should be relied on when encouraging students to study. Our folk pedagogy is a rich heritage, an inexhaustible treasure left by our ancestors, who absorbed, so to speak, the sourdough of Kyrgyz history and culture, spanning dozens of centuries. The more we hold them sacred, appreciate them and learn to study them, the more they reveal their amazing secrets to us. Therefore, it was proposed to use elements of ethnopedagogy in the Kyrgyz literature lesson. The article can be used by teachers, parents and students.
THE DEVELOPMENT OF CHILDREN'S THINKING IN THE FORMATION OF THE COMPETENCE OF YOUNGER SCHOOLCHILDREN
Authors:   Ministry of Education and Science of Kyrgyz Republic, Attokurova Chynar
Published: February 2024

In this article we will talk about mathematical and mathematical-functional financial literacy of younger schoolchildren. The development of memory and thinking of junior schoolchildren, the ability to apply the acquired knowledge in practice is considered as the basis for the formation of functional literacy, mathematical skills. The mathematics lesson discusses the development of logical thinking, verbal counting, conclusions and the depth of Webb's knowledge, problem setting, analysis, which is important for the formation of functional, mathematical-functional, financial literacy among students. In the math textbook for grades 1-4, the availability of financial literacy tasks is analyzed and it is proposed to reformulate them. Several examples and tasks for use in the classroom are analyzed, taking into account the system-activity approach to the development of competencies of younger schoolchildren.
PROBLEMS OF COMPARATIVE TEACHING OF THE EPIC "MANAS" AND THE EPIC "MAHABHARATA" IN MEDICAL UNIVERSITIES
Authors:   International Higher School of Medicine, Zayrkulova Rima
Published: February 2024

The article deals with the problems of comparative study of the epic "Manas" and the epic "Mahabharata" in higher medical educational institutions in the discipline "Manas studies". Regardless of the form of ownership, the discipline "Manas Studies" is taught in higher educational institutions. Due to the increase in the number of young people studying in medical educational institutions from the Republic of India, in order to ensure effective teaching of the discipline "Manas Studies", the comparative study of the epic "Mahabharata" and the epic "Manas" is relevant today. The comparative study of epics on the world stage plays an effective role in the development of foreign medical students, first as individuals, and then as doctors, by studying the similarities and differences between the epics of the two peoples through the prism of history, literature, traditions, culture and religion. Using historical, sociological, comparative and statistical methods of comparative teaching when teaching the discipline "Manas Studies" in higher educational institutions, comparing the epics "Manas" and "Mahabharata", we strive to preserve and transmit national values from generation to generation to students studying in the medical field.
PROBLEMS E-LEARNING IN THE BASIC EDUCATION SYSTEM OF KYRGYZSTAN
Authors:   Kyrgyz Academy of Education, Ibiraiym kyzy Aizhan , Kabylova Sveta ,   Kyrgyz National University named after Jusup Balasagyn, Kaldybaev Salidin ,   Ala-Too International University
Published: February 2024

The article discusses issues of digital education, e-learning and the use of electronic resources in general education in Kyrgyzstan. First, the problems of digitalization of education are listed, and then the problems arising in e-learning are listed. Specific problems affecting the quality of e-learning in basic education are identified, and ways to solve them are presented in order. It says that e-learning is very different from traditional learning, and writes that successful implementation of e-learning can be achieved by acquiring additional technical skills. At the end it is written that e-learning has several possibilities.
Australian Army General Service Wagon Mark X: researching the historical context of a generic artefact
Authors:   Queensland Museum, Powell Jeff
Published: February 2024

Many military artefacts are considered ‘generic artefacts’, the last remaining examples of standardised equipment produced en masse and used in their hundreds and thousands. It is rare to be able to attach a user’s name to a rifle, pick or tent. These items are interpreted as part of the background to a bigger picture of a battle or campaign. When Queensland Museum acquired a horse-drawn General Service wagon in 2013 it was to fill a niche within the Museum’s vehicle collection, adding an example of military applications to the multitude of roles performed by horses which are already represented in the collection held at the Museum’s Cobb+Co campus. The wagon was a generic representation. It is not known where this particular wagon was used in the First World War, much less who used it. The General Service wagon did not appear initially to be a promising place to start research on the early years of the Australian Army, or the ‘Homefront’ coachbuilding industry. Yet the simple question of why a wagon of English rather than local manufacture found its way into the Australian Army produced surprising insights. The story unfolded of a country ill prepared to send an army to a war overseas, and slow to comprehend the magnitude of that war. The investigation also revealed something of Australia’s role as part of the British Empire in the early years of the twentieth century.
Adolf & Du et al., 2024 v1
Authors: Adolf Frank
Published: February 2024

These protocols details methods for cloning, expression, purification and structural determination by transmission electron cryo-microscopy of 20S CPs and assembly intermediates.
POSSIBILITY OF INCREASING THE LIFETIME OF THE CHOPPING KNIFE BY APPLICATION OF PVD COATING EVALUATED IN LABORATORY CONDITIONS
Authors:   Technical University in Zvolen, Faculty of Technology, Tavodova Miroslava , Krilek Jozef ,   Technical University in Zvolen, Faculty of Technology, Falat Ladislav ,   Slovak Academy of Sciences Kosice, Institute of Materials Research
Published: February 2024

A wood is a heterogeneous material and its elements adversely affect the process of its processing. This also significantly affects the service life of tools during its processing. The aim of the contribution was, based on laboratory tests, to assess the suitability of the application of the selected coating on the chopping knife. After the basic analysis of the chopping knife, the CROSAL+ (AlCrN) coating was designed, which is an improved variant of the successfully used first generation CROSAL coating. In the experiment, samples from two knives made of tool steel X48CrMoV8-1-1 were analyzed. One sample was uncoated and the other coated. Based on the results of laboratory analyzes and tests, namely basic macroscopic and microscopic analysis of samples from tools, with semi-quantitative EDX analysis to determine the presence and content of individual chemical elements on the base material - substrate. Furthermore, the samples were tested for resistance to abrasive wear according to GOST 23.208-79. Relative resistance to abrasive wear ψabr was assessed. and hardness coefficient KT. HV and HRC hardness measurements were also carried out to determine the difference in hardness between uncoated and coated knife samples. In conclusion, it can be concluded that from the analysis and results of the measurements, the given coating for the process of processing wood by chopping can ensure the extension of the life of the tool and ensure the sufficient quality of the produced chips.
NOVEDADES EN ASTERÁCEAS COLOMBIANAS – I
Authors: Díaz-Piedrahita Santiago , Rodríguez-Cabeza Betsy Viviana
Published: February 2024

El estudio de materiales recientemente ingresados al Herbario Nacional Colombiano (COL), permitió el hallazgo de cinco nuevas especies de asteráceas pertenecientes a los géneros Lessingianthus (Vernonieae, 1 especie), Hebeclinium (Eupatorieae, 1 especie) y Pentacalia (Senecioneae, 3 especies). Se describen e ilustran estas novedades. Además se transfiere Espeletiopsis laxiflora a Coespeletia laxiflora; este cambio conlleva el registro del género Coespeletia Cuatrec. en Colombia.
Redes vivas en salud en la pandemia de covid-19: evaluación del curso de formación multiprofesional “Nós da Linha de Frente” en Manaus, Amazonas, Brasil
Authors: Therense Munique , Neves André Luiz Machado das
Published: February 2024

Este artículo presenta la evaluación del curso de intervención terapéutica en situaciones de pérdida traumática y duelo, ofrecido en línea por la Universidade do Estado do Amazonas, entre abril y agosto de 2021, para profesionales voluntarios. Se aplicó un cuestionario semiestructurado con preguntas abiertas y cerradas. El análisis de las 55 respuestas de profesionales voluntarios y 14 respuestas de personas atendidas se basó en el modelo de evaluación Kirkpatrick. Los resultados muestran el acierto teórico y práctico del curso, con una evaluación positiva en los niveles de reacción, aprendizaje, comportamiento y resultados, en la que se destacó el trabajo colectivo y la motivación de los disertantes del curso. Los principales contenidos aprehendidos fueron temas relacionados con el cuidado de la muerte y el duelo. Las conductas derivadas del curso se encuadran en los campos afectivo-social y técnico-profesional. En cuanto al impacto, hubo un predominio de la satisfacción de las personas atendidas, así como identificación de cambios provocados por la formación.
Turmocin Plus Suppresses Vascular Endothelial Growth Factor (VEGF) and Macrophage Infiltration in the Management of Perineal Wounds, Anal Fistula, Acute Anal Fissures and Haemorrhoids
Authors: Porwal Ashwin , Kundu Gopal , Bhagwat Gajanan , Nimma Ramakrishna , Chowdhury Jayeeta
Published: February 2024

Anorectal problems such as anal fistula, Crohn’s disease, haemorrhoids, and fissures are prevalent across the general population. Severe discomfort, inflammation, swelling, itching, and bleeding during defecation are common symptoms of anorectal disorders. Depending on the severity of the condition, several medical therapies or surgical procedures may be used to treat these diseases. Surgical treatments like fistulectomy and sphincterotomy or haemorrhoidectomy are highly intrusive and have a risk of recurrence. Furthermore, surgical procedures cause pain, inflammation, and perineal sores. These will lead to severe socio-economic ramifications in the patient’s life. Therefore, treatment options that aid in the reduction of inflammation, pain, and perineal wounds are critical for anorectal disease management. Herbal formulations that comprise turmeric (Curcuma longa) extract have anti-inflammatory, pain-relieving, and wound-healing properties. The purpose of the current study was to elucidate the effect of Turmocin Plus on the infiltration of inflammatory cells and the expression of pro-angiogenic factors in anorectal and lower gastrointestinal disorders. MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) and wound migration assays were performed to determine the results of Turmocin Plus on the viability and migration of inflammatory cells. The effect of Turmocin Plus on pro-angiogenic factors was determined using Western blot analysis and immunofluorescence. Further, we validate our in vitro findings in human fistula specimens using IHC. The investigation showed that Turmocin Plus inhibits immunological (RAW 264.7) cell migration while maintaining their viability. Inflammation and increased levels of Vascular Endothelial Growth Factor (VEGF) were observed in Inflammatory Bowel Disease (IBD), fistula, fissures, and higher-grade haemorrhoids. However, Turmocin Plus suppresses the VEGF expression in macrophages (RAW 264.7) cells. Furthermore, compared to untreated human fistula tissues, decreased expression of VEGF was observed in Turmocin Plus treated patient samples, validating the in vitro findings. Our study suggests that Turmocin Plus is a potent therapeutic formulation in treating fistula, perineal wounds, and Crohn’s disease.
Phytosomes: A Contemporary Method for Delivering Novel Herbal Drugs
Authors: Kanojiya Divya , Parmar Ghanshyam , Chauhan Bhavik , Gondalia Shamana , Rakholiya Monika
Published: February 2024

Our country has a wealth of Ayurvedic expertise, but only recently has its full potential been recognized. Any herbal medication’s efficacy depends on the medically active substance being delivered at an effective dosage. When given directly or externally, their bioavailability is severely constrained. With increased effectiveness, quality, and enhancement of active plant components, phytosome technology has evolved as a dedicated and hopeful means of delivering new drugs. Traditional herbal remedies have been used for a long time to successfully treat various types of illnesses, but their effectiveness has often been limited by the difficulty of getting the active compounds to their intended targets in the body. However, recent advances in herbal formulation technology have made it possible to create more efficient and targeted delivery systems for these compounds. This study emphasizes the special qualities of the phyto-phospholipid complex and how they are used in cutting-edge natural drug administration. The emphasis of the current review is on phytosome production and characterization methods, benefits, and significant developments.
Plants as Regular Phytochemical Sources of Dentistry - Formulation and Evaluation of Polyherbal Tooth Paste
Authors: Matangi Surya Prabha , Samineni Ramu , Kumar Kanhaiya , Kumar Ashutosh , Kumar Shantanu , Salmon Raju M.
Published: February 2024

Different plant components have been used in medicinal preparations in indigenous systems of medicine to clean teeth or treat oral diseases such as periodontal disease. Herbal toothpaste is equally as good at controlling plaque and gingivitis as dentifrices made according to standard formulas. Streptococcus mutants, out of all the examined bacteria, were shown towards the most susceptible to the created dentifrice, as evidenced by a zone inhibition (7-8 mm), followed by Escherichia coli (7 mm), as well as oral micro-biota (8mm). The created Poly-herbal dentifrice was successfully tested using a variety of industry-recognized standards to verify its high quality and physio-chemical qualities. According to the findings, the created Poly-herbal dentifrice shows promise for having antibacterial properties on both gramme-positive and gramme-negative organisms. Compared to completely synthetic dentifrice, it must be safer. For the development of Poly-herbal dentifrice to be proven safe and effective, more research is required. According to the study’s findings, herbal toothpaste is safer and has fewer side effects than synthetic preparations. It is also more commonly used in dentistry research. The toothpaste that is designed for oral hygiene and teeth shows antimicrobial activity against pathogens. The market preparation was contrasted with the formulation. Therefore, it demonstrates an equal amount of patronizing and engrossing passion for the promoted formulations. The development of herbal toothpaste has a promising future in the research of natural cures and general dental health.
Natural Carbonated Drink (Kombucha Tea) and its Health Benefits: A Review
Authors: Gupta Kalpana , Malhotra Yogita , Choudhary Priyanka
Published: February 2024

Kombucha is a traditional carbonated tea obtained by fermentation with Symbiotic Culture of Bacteria and Yeast(SCOBY). The SCOBY consumes sugar in tea and produces enzymes and organic acids. The process typically takes one or two weeks and changes tea into a fizzy, slightly sour fermented (generally non-alcoholic) beverage. Kombucha contains chemical and biologically active compounds such as polyphenols, antioxidants, and a source of probiotics (Lactobacillus) that show health-promoting properties. Kombucha has potential health benefits, but not all have been proven in studies with humans. It is being commercialized in India and can be prepared at home easily with precautions. It can be prepared by fermenting sweetened green or black tea using a Symbiotic Culture of Bacteria and Yeast (SCOBY). As the fermentation proceeds, the yeast in the SCOBY breaks down the sugar present in the tea and releases friendly probiotic bacteria. In this paper, we highlighted various factors affecting fermentation, where the pH shows a significant impact on the tea quality. Herein, we have also discussed the health benefits and toxicity of Kombucha tea along with the recent literature.
A Review of the Phytochemical and Pharmacological Characteristics of Hernandia nymphaeifolia
Authors: Das Sumana , Khan Afsana , Bishal Amlan , Badyopadhya Bratati , Mondal Mohini , Datta Aveek , Jha Shilpy , Das Raneet , Debnath Biplab
Published: February 2024

Since ancient times, medicinal plants have been the primary source of most medications. In actuality, a large number of the medications that are now on the market may be obtained either directly in extract form or in modified synthetic form. As phytoconstituents, which are employed by plants to carry out biological processes and defend us from predators like viruses, fungi, and other microbes, they are naturally able to produce goods that are helpful for humans. Hernandia nymphaeifolia is a traditional medicinal plant that is used in several traditional remedies to treat several ailments. The extracts from various portions of the plant have excellent therapeutic effectiveness. Numerous pharmacological investigations have demonstrated this plant’s capacity to display anti-cytotoxic, anti-inflammatory, anti-platelet aggregation, vasodilator, antioxidant, anti-microbial, and Ca2+ signalling properties. The current study covers a thorough examination of the plant’s systematic botanical position, phytochemical analysis, investigations into the plant’s pharmacological activity, and therapeutic uses.
Management of Kotha Roga (Necrotizing Fasciitis) by Modified Ksharapichu (Wound Packing): A Case Report
Authors: Shrivastav Pooja , Yawale Suyog , Tichkule Suraj , Parwe Shweta
Published: February 2024

The present case report was a 25-year-old male patient with severe pain at the right index finger, fever, oedema, and discharge, not having any history of surgery, hypertension, diabetes, or any systemic disorder was diagnosed with kotha roga (necrotizing fasciitis). Presently available treatment for this is broad-spectrum intravenous antibiotics, appropriate hydration support, and meticulous surgical debridement with regular wound packing. But because of contaminated wounds and poor prognosis, herbal therapies have a possibility to cure kotha as they are readily available, and inexpensive. In this case, a kshara formulation i.e., modified ksharpichu was chosen as an atrial medication to be applied locally after everyday cleaning and dressing. It was observed that ksharpichu acted as a debriding agent and healing as well. The case was followed up for 30 days. This study employed pretty simple criteria to gain preliminary observations on the effectiveness of this Kshara taila on kotha roga.
Sinapis alba ln Status Epilepticus: A Preclinical Study
Authors: Nayak Gayatri R. , Parida Amrita , Hegde Shreya , Shenoy Smita , Mohandas Rao K. G. , Shivakumar Reddy K. , V. Manju
Published: February 2024

In this study, the anti-convulsant effect of Sinapis alba seed oil and its combination with sodium valproate was evaluated in Wistar albino rats using the lithium-pilocarpine Status Epilepticus (SE) model. The experimental groups included: Group I - normal control; Group II - disease control; Group III - Sinapis alba seed oil; Group IV - sodium valproate; Group V - Sinapis alba seed oil + ½ dose sodium valproate. Antioxidant markers and Brain-Derived Neurotrophic Factor (BDNF) levels were measured from the brain samples. The pathological changes were also determined using Cresyl violet staining. Sinapis alba oil did not prevent rats from developing status epilepticus but reduced the intensity and frequency of occurrence. Oil administration increased antioxidant levels and decreased lipid peroxide levels as well. The combination of oil and sodium valproate showed a synergistic effect in the status epilepticus model. The study results show that Sinapis alba can be used as an adjuvant in status epilepticus along with other antiepileptic drugs.
Investigation of the Effect of Coconut Palm Sugar on Metabolic Disorders in Experimental Diabetic Rats
Authors: Patel Shraddha , Navale Archana
Published: February 2024

Diabetes is a metabolic disorder with many different underlying factors. Humans can develop Type 1 diabetes, which is brought on when the immune system assaults and destroys insulin, and Type 2 diabetes, which can be brought on by several variables, the most important of which is lifestyle, as well as by different genotypes. Due to the presence of polyphenols, which have high antioxidant qualities, Coconut Palm Sugar (CPS) is nutritious and has a good potential for managing diabetes. In this investigation, we took the STZ-Nicotinamide model for diabetes induction. In normal rats (Phase 1) and diabetes-induced rats (Phase 2), After exposure to table sugar and coconut palm sugar, we measured a variety of factors, including body weight, food intake, water consumption, blood sugar level, insulin level, insulin resistance, lipid profile, atherogenic index, and insulin resistance.
Efficacy of Chatuprasrutik Basti in Management Of Oligospermia – A Pilot Study
Authors: Magar Sagar F. , Nakade Mamata M. , Kshirsagar Rahul , Pawar Snehalata
Published: February 2024

Oligospermia is one of the most common reasons for infertility in day-to-day life. Infertility is a widespread issue that affects 8-12 % of couples globally on average and is getting worse day by day. It was observed that the pathology is found in approximately incidence of 60% males alone in infertile couples. In Ayurveda, Oligospermia can be correlated with Shukra-Alpta. Bastikarma is considered to be having particular action on Shukra Dhatu and Chatuprasrutik Basti is explained as Shukrakrut Basti in Charak Samhita, So in this study, Chatuprasrutik Basti was selected in the management of Oligospermia.
Aim: This clinical investigation looked into how Chatuprasrutik Basti affected the number of sperm in patients with infertility.
Study Design: This was interventional clinical research with one arm.
Materials and Methods: Chatuprasrutik Basti was administered for two cycles of Basti of 6 days each with a month gap in Seven newly diagnosed cases of Oligospermia from the outpatient Department of Panchakarma at SST’s Ayurved Mahavidyalaya in, Sangamner, Ahmednagar, Maharashtra, India.
Statistical Analysis: The “Student paired t-test” was used statistically to analyze the data.
Results: At the conclusion of therapy, a significant (p<0.05) result was found in the evaluation of an objective parameter, specifically sperm count, and a significant result was not found in the evaluation of the factor sperm motility as p>0.05.
Conclusion: Chatuprasrutik Basti is effective in the management of Oligospermia considering the factor of sperm count.
The Socio-Political Views of P.‑Sh. Leveque (Problem of Russian «Civilization»)
Authors:   Saratov State University, Ilichenko E. V.
Published: February 2024

In the article deals with socio-political views of one of brightest representatives of the French Enlightenment era, the historian of Russia P.-Sh. Leveque. The great interest is the analysis of the views by Leveque on the most urgent problems of state and public arrangement of Russia of the XVIIIth century: the reign of Peter I and Catherine II. In considering the topic judgments of the French historian with the ideals of the one of the leading philosophers of the Enlightenment era, D. Diderot were compared.
French Traveler E. Valbezen about Englishmen in India in the Middle of the 19th Century
Authors:   Saratov State University, Overina G. Y.
Published: February 2024

This article examines the image of India, as it was seen by the French traveler. The author primarily focused at his perception of British colonial policy and its negative consequences for India. The rivalry between France and Britain resulted, among other things, in the critical approach toward the British style of governance in Indian colonies, which was perceived as outrageous and hard for the natives. Such image of Britain rest on the strong ground of competition between France and Britain in South-East Asia was pretty widespread in French society because of a number of critical publications in journals and newspapers. One of these publications is the subject of the author’s research represented in the article.
I.A. Fessler in Volga Region
Authors:   Saratov State University, Gorbachev D. V.
Published: February 2024

In Russian and European historiography D. V. Gorbachev’s article presents the first example of a critical analysis dealing with memoirs of I. A. Fessler, being a German thinker, public and religious figure, writer and freemason. The author purposes to estimate the reliability of information about Fessler’s stay in Saratov Volga region in 1810–1820th which is described in these memoirs. In connection with this aim author ascertains the subjects, which are passed by Fessler over (circumstances of his journey from St. Petersburg to Saratov province, Saratov Freemasonry, conflicts connected with a church practice of the Volga Germans).
Work G.I. Chernyshevsky over Drawing up of «The Church Historical and Statistical Description of the Saratov Diocese» (1850–1856)
Authors:   Museum of N.G. Chernyshevsky, Zaharova I.E.
Published: February 2024

Drawing up in the middle of XIX in history-statistical descriptions of dioceses across all Russia under the Synod project was the important stage in development of regional history and study of local lore. On the basis of archival materials resulted in article it is possible to track a technique of work of archpriest G.I. Chernyshevskii over drawing up of statistical research on stories of the Saratov diocese.
Incompressible Schrödinger Flow with Heat-Transfer: An Introduction to the Analysis of Isotropic Fluid Dynamics in Sobolev Spaces for an Immersed Arbitrary Isothermal Geometry
Authors: Santos Rômulo Damasclin Chaves dos , Sales Jorge Henrique de Oliveira
Published: February 2024

This research investigates the intricate interplay of incompressible Schrödinger flow, heat-transfer, and the presence of an immersed isothermal body. The mathematical framework encompasses the Schrödinger equation for incompressible fluids, the heat transfer equation, and introduces a term that represents the thermal influence of an immersed isothermal geometry. Emphasizing the modeling and analysis of isotropic fluid dynamics, the study seeks to unravel the subtle relationship between the principles of quantum mechanics and the classical behavior of fluids. The initial discoveries produce an important theorem that leads the name of the authors, allowing new and valuable insights into the effects of the isothermal body immersed in a fluid medium. As a result, it was found that the term temperature source offers a unique perspective at the intersection of quantum mechanics and fluid dynamics.
Distance Learning of a Foreign Language in the Context of Neuropedagogical Factors
Authors: Lakhmotova Yuliia , Sadovets Olesia , Orlovska Olha , Martynyuk Olena , Myroshnychenko Viktoriia , Lebedieva Liudmyla
Published: February 2024

The relevance of the article lies in the fact that in our time, the organization of distance learning when learning a foreign language is extremely relevant.
The purpose of the article: to find out the main terms and forms of distance learning; consider the features of online education; explore platforms for the convenient organization of online learning; highlight the advantages and disadvantages of distance learning when learning a foreign language as an aspect of neuropedagogical training.
Work methods: compare the analysis of literary sources on the research problem; to systematize the researched; compare the benefits of distance learning.
The novelty of using mobile technologies, which is extremely effective and necessary when learning a foreign language online.
Results: synchronous, asynchronous and mixed learning are distinguished among distance learning forms. E-learning is a basic form that has both advantages and disadvantages. Blackboard is widely used among e-learning platforms.
Conclusion: the role of the teacher who uses interactive forms of learning for mobile learning has changed. The Internet provides a wide selection of modern materials for learning a foreign language. Students and teachers accept online education with desire and interest, increase their information and communication competence. Physical activity is necessary for long-term work on educational platforms.
The Importance of Involving a Multidisciplinary Team in the Management of a Patient Diagnosed with TB, Associating Erythema Nodosum
Authors: Mihailov Oana Mariana , Mihailov Raul , Dinu Ciprian , Ciubara Alexandru Bogdan
Published: February 2024

Tuberculosis (TB) is an important and topical problem at global level, so it remains a challenge for public health policies . According to the World Health Organization (WHO), in 2018, about 10 million new TB cases worldwide were estimated. Of these, 11% are children under the age of 15. In addition to these alarming data, TB is responsible for 130,000 deaths per year in children and it is estimated that there are approximately 1 million TB-cases in the global population of children, being one of the top 10 causes of death in children worldwide.  According to the WHO, there are economic, social, cultural, ethnic/racial, psychological and behavioral factors that interfere with the occurrence of diseases, and these factors are attributed to the persistence of infectious diseases such as TB in the population, even today. Numerous specialized studies strengthen the hypothesis of associating social vulnerability with TB emergence and distribution in the community.
Therefore, the development of more accurate estimates of pediatric TB cases is an urgent need for public policy scheduling and resource allocation and, consequently, for reducing morbidity and mortality from TB among children.
Reading Neurocognitive Disorder
Authors: Mihailov Liliana , Diaconu Ioan Florin , Ichim Vlad , Mutică Mihai , Pîrvu Bogdan , Poroch Vladimir
Published: February 2024

The multiple uses of Humanities in teaching Medicine need hardly detailing; suffice to say that a number of top Medical Schools have included Medical Humanities in their curricula. In this context we will consider the way Eugène Ionesco can be put to good use when it comes to teaching neurocognitive disorder; his theatre, come to think of “The Bald Soprano,” focuses on non-sequiturs, dislocated language and distorted logic – all of these being unfailing expressions of a cognitive impairment or even demise.
Dental Anxiety- a Prospective Study among Medical and Non-Medical Subjects
Authors: Moroianu Marius , Matei Madalina Nicoleta , Moroianu Lavinia-Alexandra , Curis Cecilia , Mihailov Raul , Mihailov Oana Mariana
Published: February 2024

The subject of anxiety related to dental treatments is recognized and long debated in medical literature. There are various motivations, starting with individual, age-related, social, economic or strictly medical reasons. Considering the medical and psychological importance of oral health that impact the whole organism health, there is an increasingly sustained, interdisciplinary concern, with the involvement of dentists, generalists, psychologists or psychiatrists. This situation is quantified at the individual and social level with reference to both the financial costs and the organic and psychological suffering determined by this medico-psycho-social problem. This is why the authors of this article proposed in the current study to determine if there is a difference in terms of anxiety towards dental treatments in subjects trained from a medical point of view versus people without medical instruction. The study used an online questionnaire and was carried out over a period of one month in the year 2023. The data were processed with the help of LibreOffice Calc and Microsoft Excel. The conclusions of the study revealed that poor oral health can serve as a precursor to anxiety and depression, creating a link between oral hygiene and mental well-being. Oral pain, embarrassment and the resulting self-consciousness can contribute to feelings of anxiety and depression, feelings that exist no matter if there were subjects trained in medical field or not, therefore individuals may have difficulty socializing, communicating, and maintaining a positive self-image.
The Prevalence of Burnout Syndrome Among Emergency Department Nurses
Authors: Moscu Cosmina-Alina , Vlad Ciprian , Zainea Pusica , Ciubara Anamaria
Published: February 2024

Introduction. Burnout syndrome is a manifestation of chronic stress characterized by emotional, mental and physical exhaustion, caused by occupational stressors and is represented by three dimensions: emotional exhaustion, depersonalization and decreased personal performance. The COVID-19 pandemic had a major impact on the medical system, with a psychological impact on the medical staff. This emotional and physical exhaustion is also found among nurses.
Material and methods. We studied a total of 112 participants receiving 80 valid questionnaires. This was a descriptive, cross-sectional study of the medical staff within the UPU-SMURD section of the County Emergency Clinical Hospital “St. Ap. Andrei” Galați, who is in the front line in the fight against coronavirus. After signing an informed consent, the participants completed a socio-demographic questionnaire and the MBI-HSS (MP) questionnaire to assess their level of burnout.
Results. The aim of our study was to identify the prevalence of burnout syndrome among emergency department nurses in the context of the Covid-19 pandemic. The study found that 46.2% of nurses suffer from an average level of burnout, and only 32.5% suffer from a high level. Also, emotional exhaustion is directly proportional to professional experience and age.
Conclusions. The prevalence of burnout syndrome is high, with most front-line nurses suffering from moderate to severe burnout.
The Power of Religious Faith as a Predictor of Autonomy, Community, and Divinity Ethical Values
Authors: Nicoara Romulus-Dan , Ana-Maria Nicoară , Codruța Alina Popescu
Published: February 2024

This article investigates the influence of religious faith on ethical values (autonomy, community, and divinity), and specifically considers the predictive role in shaping individuals' orientations toward autonomy, community, and divinity. Study examines the ways in which adherence to religious beliefs molds ethical perspectives. The research employs a multidimensional framework to assess the correlation between religious faith and values associated with personal autonomy, communal responsibility, and the sacred. Understanding the power of religious faith as a predictor of ethical values has implications for fostering a deeper comprehension of diverse moral frameworks and facilitating interfaith dialogue. The article underscores the importance of recognizing and respecting the role of religious beliefs in shaping ethical convictions, thereby contributing to a more inclusive and informed discourse on morality in a pluralistic society.
The Role of Current Computer Technologies in Developing Professional Competence of Music Teachers: A Model of a Personalized Educational Environment
Authors: Pavlenko Oleksii , Rastruba Tetiana , Huseinova Larysa , Khomenko Leonid , Pelekh Khrystyna , Koval Olena
Published: February 2024

The importance of the article lies in the fact that the profession of school music teacher today needs to create its own updated competence model of personal educational environment taking into account digital transformation and computerization of general education. The information competence of the music teacher, the issues of his professional development in working with music and computer technologies are taken into account. Analyzed the possibility of building a personal educational environment in the era of postmodern (including electronic) and their application in further professional activities. The author analyzes the possibility of introducing modern computer technology as a resource for the formation of musical needs of the teacher of the educational institution. In addition to professional competencies, some general requirements for music teachers today, which can be grouped into four groups: general professional, communicative, behavioral and analytical. The article presents a model of university music education in the postmodern era; ways of acquiring professional competence of a music teacher are considered; the stages of creating a model of personal educational environment of a music teacher in the postmodern era are described; the role of professional competence of a music teacher in the postmodern personal educational environment model is defined; the role of current music and computer technologies (MCT) in creating a model of personal educational environment of a music teacher was determined.
The Influence of Physical Activity Regime on Body Composition in Teenagers With and Without Intellectual Disabilities
Authors: Puni Alexandru-Rareș , Cojocariu Adrian , Abalașei Beatrice-Aurelia , Popescu Lucian , Martinaș Florentina-Petruța , Bulduș Codruța-Florina , Tătăranu Elena , Popa Cristian , Ene-Voiculescu Carmen , Pârvu Carmen , Ungurean Bogdan-Constantin
Published: February 2024

This study aims to assess several morphofunctional parameters in female teenagers with and without intellectual disability to characterise normality and its disturbances. More precisely, the purpose was to examine the factors contributing to the differences in body composition elements between groups, such as the physical activity level. To evaluate these parameters, we used bioelectrical impedance analysis technology (BIA), most commonly used in studies concerning body composition because it is non-invasive, quick, with high data fidelity; it can be easily moved to various locations and applied straightforwardly among populations with diverse types of intellectual disability. Our research sample comprised 212 subjects (boys and girls) aged 17.1±0.6, divided into six groups by gender and type of intellectual disability.  The study found influences of physical activity level on body composition components. In addition, we report a highly significant relationship for p<0.05, body mass index and the independent variable (No. of min./week) in some groups.
Unmasking Burnout in Romanian Primary Care: Implications for Healthcare Careers and Well-Being in Pandemic Times
Authors: Silistraru Ioana , Olariu Oana , Ciubara Anamaria , Rosca Stefan , Azoicăi Doina , Alexa Anisia-Iuliana , Severin Florentina , Zainea Pusica , Anghel Lucretia , Danila Radu , Ciureanu Ioan-Adrian
Published: February 2024

This cross-sectional study investigates primary care physicians' intentions to change occupations and the presence of burnout in Romania in the pandemic. The research was carried out using an updated version of the MBI-Human Services Survey for Medical Personnel - MBI-HSS (MP) questionnaire. Our sample group consisted of 95 Romanian family doctors, of which 85 were female and 10 were male. 70.58% of female respondents reported having a high level of emotional Exhaustion, while 100% of male participants reported having the same raised levels of Exhaustion. 50% of men and 34.11% of women reported significant levels of Depersonalization, whereas 41.17% of female respondents indicated the lowest levels of Depersonalization.
Regarding personal accomplishment, 40% of men and 27.05% of women indicated they had high levels of PA. Based on statistical analysis, there is no significant correlation between gender and burnout dimensions, indicating that primary care physicians are at risk for burnout regardless of gender. The study also looked at an inclination to switch to a different medical speciality because of burnout. Of the participants, 55.78% said they would opt for the same specialisation again, 29.47% said they were unsure, and 33.68% said they would not choose the same medical profession again if given the chance. According to the findings, there appears to be a positive correlation between Depersonalization and the intention to change careers. Specifically, higher Depersonalisation scores were associated with a higher probability of considering changing careers. Emotional Exhaustion and personal achievement, however, did not substantially correlate with changing professions.