bluuebunny/crossref_metadata_2025 huggingface dataset:
PURION® processed human amnion chorion membrane allografts retain material and biological properties supportive of soft tissue repair
Authors: Moreno Sarah , Massee Michelle , Campbell Shauna , Bara Heather , Koob Thomas J , Harper John R
Published: April 2024

The reparative properties of amniotic membrane allografts are well-suited for a broad spectrum of specialties. Further enhancement of their utility can be achieved by designing to the needs of each application through the development of novel processing techniques and tissue configurations. As such, this study evaluated the material characteristics and biological properties of two PURION® processed amniotic membrane products, a lyophilized human amnion, intermediate layer, and chorion membrane (LHACM) and a dehydrated human amnion, chorion membrane (DHACM). LHACM is thicker; therefore, its handling properties are ideal for deep, soft tissue deficits; whereas DHACM is more similar to a film-like overlay and may be used for shallow defects or surgical on-lays. Characterization of the similarities and differences between LHACM and DHACM was conducted through a series of in vitro and in vivo studies relevant to the healing cascade. Compositional analysis was performed through histological staining along with assessment of barrier membrane properties through equilibrium dialysis. In vitro cellular response was assessed in fibroblasts and endothelial cells using cell proliferation, migration, and metabolic assays. The in vivo cellular response was assessed in an athymic nude mouse subcutaneous implantation model. The results indicated the PURION® process preserved the native membrane structure, nonviable cells and collagen distributed in the individual layers of both products. Although, LHACM is thicker than DHACM, a similar composition of growth factors, cytokines, chemokines and proteases is retained and consequently elicit comparable in vitro and in vivo cellular responses. In culture, both treatments behaved as potent mitogens, chemoattractants and stimulants, which translated to the promotion of cellular infiltration, neocollagen deposition and angiogenesis in a murine model. PURION® processed LHACM and DHACM differ in physical properties but possess similar in vitro and in vivo activities highlighting the impact of processing method on the versatility of clinical use of amniotic membrane allografts.
Are Large-Scale Data From Private Companies Reliable? An Analysis of Machine-Generated Business Location Data in a Popular Dataset
Authors: Grigoropoulou Nikolitsa , Small Mario L.
Published: April 2024

Large-scale data from private companies offer new opportunities to examine topics of scientific and social significance, such as racial inequality, partisan polarization, and activity-based segregation. However, because such data are often generated through automated processes, their accuracy and reliability for social science research remain unclear. The present study examines how quality issues in large-scale data from private companies can afflict the reporting of even ostensibly uncomplicated values. We assess the reliability with which an often-used device tracking data source, SafeGraph, sorted data it acquired on financial institutions into categories, such as banks and payday lenders, based on a standard classification system. We find major classification problems that vary by type of institution, and remarkably high rates of unidentified closures and duplicate records. We suggest that classification problems can affect research based on large-scale private data in four ways: detection, efficiency, validity, and bias. We discuss the implications of our findings, and list a set of problems researchers should consider when using large-scale data from companies.
Gender-Ambiguous Voices and Social Disfluency
Authors: Mohsenin Shahryar , Munz Kurt P.
Published: April 2024

Recently, gender-ambiguous (nonbinary) voices have been added to voice assistants to combat gender stereotypes and foster inclusion. However, if people react negatively to such voices, these laudable efforts may be counterproductive. In five preregistered studies ( N = 3,684 adult participants) we found that people do react negatively, rating products described by narrators with gender-ambiguous voices less favorably than when they are described by clearly male or female narrators. The voices create a feeling of unease, or social disfluency, that affects evaluations of the products being described. These effects are best explained by low familiarity with voices that sound ambiguous. Thus, initial negative reactions can be overcome with more exposure.
Adaptive prescribed performance tracking control for uncertain nonlinear systems with unknown backlash-like hysteresis
Authors: Zhao Wei , Zhu Shan-Liang , Zhou Ya-Feng , Han Yu-Qun , Wang Wen-Wu , Zhou Qing-Hua
Published: April 2024

In this paper, an adaptive prescribed performance tracking control(PPTC) problem of uncertain nonlinear systems with unknown hysteresis input is investigated. For the purpose of implementing the PPTC, a performance function and an error conversion function are introduced. Moreover, a backlash-like hysteresis model is adopted to describe the hysteresis nonlinearity, which makes the controller design feasible. Additionally, by converting the backlash-like hysteresis model into a linear model with bounded error, the difficulties caused by hysteresis behavior on controller design are settled. Thus, integrating multi-dimensional Taylor network(MTN) approximation technique into adaptive backstepping method, an adaptive control scheme for uncertain nonlinear systems is proposed. Apart from ensuring that all signals of the closed-loop system keep bounded, the proposed control scheme not only makes the tracking error converge to an arbitrarily small neighborhood around the origin, but also guarantees the tracking error trajectory within the limits set by PPTC. Ultimately, two simulations are applied to verify the validity of the proposed control scheme.
Kangaroo Mother Care in India: Down the Memory Lane
Authors: Udani Rekha H. , P. N. Suman Rao , Bergh Anne-Marie
Published: April 2024

India has been at the forefront of kangaroo mother care (KMC) promotion and implementation in the past three decades. In this article, we describe the history of KMC implementation in India and how KMC has become the standard of care for all preterm or low-birth-weight infants. We distinguish three phases in the development of KMC implementation and scale-up: the early years, the slow middle years and becoming a leader.
Birth trauma in a population requiring inpatient mental health care in the postpartum period
Authors: Isobel Sophie , Emerton Alexandra , Lim-Gibson Sylvia
Published: April 2024

Objective

This study explores rates of birth-related symptoms of trauma in a population of parents experiencing severe perinatal mental illness.

Method

Birthing-parents admitted to a perinatal inpatient unit completed birth trauma measures on admission which were descriptively analyzed.

Results

The population had higher rates of birth-related potentially traumatic events and trauma-related symptoms than the general population.

Conclusions

The findings highlight that assessing for and responding to experiences of birth trauma is highly relevant to an inpatient perinatal population.
The Development of Elder-Governed Adjuvant Cultural Therapy for Aboriginal and/or Torres Strait Islander Young People With Mental Health Conditions
Authors: Vance Alasdair , McGaw Janet , O’Rorke Di , White Selena , Eades Sandra
Published: April 2024

A 10-year review of the 2008 Council of Australian Governments’ (COAG) Close the Gap Strategy identified the lack of involvement of Indigenous people in developing policies as a key reason health disparities persist. It also posits that disconnection from Country and culture have been crucial factors. Physical and mental health cannot be separated from spiritual health and well-being amongst Indigenous Australians. This article describes the co-development of a cultural enrichment research study with Indigenous Elders, health service leaders, and community members that places culture at the centre of care to augment traditional Western mental health management. The study has been overseen and nurtured from its inception by a governance board of Traditional Custodian Elders and an Advisory Group of Indigenous health workers. Qualitative data were collected through community ‘zoom- yarns’ between an Indigenous research assistant and 44 community members during COVID-19 lockdowns. These yarns were analysed through an innovative, constructivist, multi-perspectival discursive grounded theory method. Findings have led to an Elder-governed adjuvant cultural therapy which is currently being trialled and will be evaluated using the same multi-perspectival discursive grounded theory research methodology. One third of all Indigenous Australians now live in capital cities, so developing models to bring culture and Country into urban health facilities are becoming increasingly important. The Indigenous-led research approach outlined in this paper suggests a model for engaging Indigenous communities that mainly distrust Western research and have been failed by Western mental health care. It has the potential to shape future policy.
Control theory for fractional differential Sylvester matrix equations with Caputo fractional derivative
Authors: Sadek Lakhlifa
Published: April 2024

In this manuscript, we introduce the concept of first-time controllability and observability concerning fractional differential Sylvester matrix equations employing the Caputo fractional derivative. Our work establishes necessary and sufficient conditions for controllability and observability, wherein controllability equates to having a controllability matrix with full rank and observability aligns with an observability Gramian matrix that is nonsingular. Furthermore, we provide several theorems addressing the observability of fractional differential Sylvester matrix equations. Finally, we offer two illustrative examples to demonstrate the efficacy and application of our established results.
Anti-plane waves in a liquid-loaded piezo-flexo-electric layered model with interface energy
Authors: Singh Sonam , Singh Abhishek K
Published: April 2024

The basic design of a Love wave (LW) bio-sensor contains the loading of a viscoelastic liquid on top of a layered structure with distinct viscoelastic properties. Changes in the characteristics of the propagating acoustic wave caused by biochemical interactions at the sensing area can be detected at the output Inter digital transducer (IDT). The propagation of the anti-plane (AP) wave is discussed in this work in a layered structure of piezo-flexo-electric (PFE) layer bonded with a PFE half-space having a soft reinforced layer at the interface. The free surface of the PFE layer is loaded with viscous liquid. The viscosity of the loaded liquid introduces losses and results in the damping of the wave. For the formulation of the problem with interface energy, the Gurtin–Murdoch approach is used. Using suitable conditions, a dispersion relation for propagating waves is derived in complex form. On separating the dispersion relation in real and non-real parts, the expressions relating the phase and damp velocities with wave number are derived. The obtained theoretical results are portrayed for the numerical data of PFE materials and distinct data of the interface layer. The obtained results are validated with pre-existing literature.
Prevalence of Soil-Transmitted Helminth Infections and Associated Risk Factors Among School Children in Dembecha Town, Ethiopia
Authors: Aemiro Aleka , Menkir Sissay , Girma Abayeneh
Published: April 2024

Soil-transmitted helminth (STH) infections are among the most common infections that affect the poorest and most deprived communities. In most developing countries, children aged 5 to 15 years are at risk for chronic helminth infection and associated morbidity. This study aimed to determine the prevalence of STH infections and associated risk factors among three government elementary schools in Dembecha town, Ethiopia. We conducted a school-based cross-sectional study involving 316 participants between November 2019 and March 2020. A systematic random sampling method was used to select study participants from the study schools. Data related to the sociodemographic characteristics of the study participants and risk factors for STH infections were collected using a pretested questionnaire survey. Parasitological examinations of stool samples were performed using the formal-ether concentration method. Study participants aged 5 to 15 years were enrolled in this study. The overall prevalence of STH infection was 21.5% (68/316). Ascaris lumbricoides ranked highest, with a prevalence of 11.4%, followed by hookworms 7.3%, Trichuris trichiura 1.9%, and Strongloides stercoralis 0.9%. Age groups of 10-15 years (AOR =3.109; 95% CI: 1.033, 9.350), residence in Kebele 2 (AOR =2.990; 95% CI: 1.082, 8.264), illiterate mothers (AOR =4.689; 95% CI: 1.410, 15.59), and a family size of 4-6 (AOR =3.286; 95% CI: 1.299, 8.313) were significantly associated with STH infections. The prevalence of STH infections remains an important health issue for study participants. Therefore, school deworming programs twice a year are crucially needed until the prevalence falls below the level of public health importance.
Examining the correlates of cigarette smoking, e-cigarette use and dual use among Canadian post-secondary students
Authors: Fagan Matthew James , Zhan Jian Kun , Wunderlich Kelly B. , Faulkner Guy
Published: April 2024

Many Canadians use nicotine products such as cigarettes and e-cigarettes. A particular subpopulation of concern is post-secondary students given they have a higher prevalence of use. Many correlates of cigarette smoking and e-cigarette use have been identified. However, less focus has been on examining the correlates of cigarette smoking, e-cigarette use and dual use. This study explores the correlates of different nicotine modality use in post-secondary students. Using data from the Canadian Campus Wellbeing Survey (CCWS; n = 27,164), a multi-level nominal regression assessed the correlates of nicotine modality use. In comparison to individuals who were <20, individuals 20-24 (OR = .448, 95% CI .321, .625), 25-29 (OR = .140, 95% CI .093, .212), 30-34 (OR = .076, 95% CI .046, .125) and over 35 (OR = .041, 95% CI .024, .071) had lower odds of e-cigarette use compared to cigarette smoking. Identifying as a woman (OR = 1.553, 95% CI 1.202, 2.006), non-heterosexual (OR = .642, 95% CI = .485,0.851), current cannabis user (OR = 1.651, 95% CI 1.296, 2.104), and being an international student (OR = .350, 95% CI .251, .487) also impacted the odds of e-cigarette use vs only cigarette smoking. When considering dual use vs cigarette smoking, individuals aged 20-24 (OR = .491, 95% CI .337, .717), 25-29 (OR = .221, 95% CI .137, .357), 30-34 (OR = .163, 95% CI .091, .292) and over 35 (OR = .122, 95% CI .065, .230) had lower odds than individuals <20. Current cannabis use (OR = 1.680, 95% CI = 1.209, 2.138), binge drinking (OR = 1.885, 95% CI 1.384, 2.568), and international student status (OR = .689, 95% CI .476, .996) also impacted cigarette smoking vs dual-use. Overall, a minority of young adults (11.5%) at post-secondary institutions in our sample use nicotine products, and the higher prevalence of e-cigarette use warrants continued monitoring. Health promotion campaigns addressing e-cigarette use are required. Additionally, tailored intervention efforts could prioritize the treatment needs of international students studying in Canada.
Replicating the rolling-sliding dynamics of cam-roller contacts in large-scale hydraulic drivetrains: A small-scale approach
Authors: Amoroso Pedro , van Ostayen Ron AJ , de Rooij Matthijn B
Published: April 2024

The rolling-sliding dynamics of large-scale cam-roller contacts are strongly influenced by the inertia of the roller, particularly when slippage occurs. Slippage can potentially impact the reliability of these rolling interfaces. This study introduces an approach to replicate the rolling-sliding dynamics of cam-roller contacts in a large-scale hydraulic drivetrain, on a small scale. For that, we have upgraded our two-roller tribometer to enable cyclic loading, allow the application of resisting torques, and generate inertia torques. These are three essential elements required to mimic the dynamics observed at large scales. A method has been proposed for scaling the roller inertia accordingly. Furthermore, we have implemented a modeling framework from previous work to make predictions under various dynamic conditions. The results show that our small-scale approach can replicate five key characteristics anticipated at a large scale, including those linked to slippage. Small increments in the resisting torque significantly increased the slide-to-roll ratio (SRR) and peak traction force, among others. The simulations also predicted these effects, capturing trends and producing reasonable predictions of the magnitude and relevant features of key parameters. The use of cyclic loading, extra inertia, and adjustable resisting torques, effectively generated repeatable and controllable dynamic rolling-sliding conditions. Our work is significant for the design and development of novel large-scale hydraulic drivetrains. Our findings highlight the importance of reducing slippage at low contact forces to prevent the brusque change in the rolling conditions during the high contact force phase. By doing so, surface damage and detrimental dynamic effects can be prevented.
Time-dependent reliability assessment and optimal design of corroded reinforced concrete beams
Authors: Li Junxiang , Guo Xiwei , Zhang Xinxin , Wu Zijun
Published: April 2024

It remains a significant challenge to quantitatively describe the corrosion of reinforced concrete (RC) structures under chloride penetration. Moreover, when considering uncertainties throughout the life cycle of corroded RC structures for assessing their safety, reliability, and optimal design, the complexity of the problem intensifies. To address these issues, this paper studies the time-dependent reliability analysis and optimal design of corroded RC beams. At first, the time-dependent reliability of beams is investigated by considering both the serviceability limit state (SLS), which corresponds to the corrosion initiation of the reinforced steel, and the ultimate limit state (ULS), associated with the bending failure of the beam. This analysis takes into account the time-dependent chloride diffusion coefficient and incorporates a stochastic process. The reliability is evaluated using the Monte Carlo Simulation (MCS) method and the cumulative distribution function (CDF) method. Subsequently, a time-dependent reliability-based design optimization (TRBDO) problem is formulated, and the PSO-MCS, a methodology incorporating a particle swarm optimization (PSO) algorithm and MCS is adopted to solve it. After optimization, the initial cost of the specific RC beam is reduced from 1351.879€ to 1247.075€, while the time-dependent reliability within [0, 100] years is improved from 0.6057 to 0.6508. The effectiveness of the CDF, MCS and PSO-MCS methods are demonstrated through reliability analysis and design examples of corroded RC beams.
Exploring the presence of Cymraeg on TikTok
Authors: Cunliffe Daniel
Published: April 2024

Many of the world’s languages are endangered or vulnerable. For some of these languages, a presence in technological domains can illustrate vitality and demonstrate relevance to the lives of younger speakers. A presence on social media is often seen as particularly significant for younger speakers due to their high levels of social media use. This article explores the presence of Cymraeg (the Welsh language) on TikTok. Through the analysis of a corpus of 200 videos, the article reveals a complex and richly bilingual content space with considerable intermingling of Cymraeg and English. Commenting on videos and engaging in a text-based conversation with the content creator and other audience members is shown to be a significant activity. The corpus demonstrates that Cymraeg is being used, taught, discussed and promoted on TikTok. This article contributes to an ongoing assessment of the digital vitality of Cymraeg and extends our understanding of the role that social media can play in supporting the sustainability and vitality of minority languages.
Investigation of the effect of injection rate shaping on combustion and emissions in heavy-duty diesel engine under steady and transient conditions
Authors: Sun Haibo , Zheng Zunqing , Li Jincheng , Li Gang , Wang Xiaohui , Yao Mingfa
Published: April 2024

The fuel injection rate (ROI) is a crucial factor that affects the combustion and emissions of diesel engines. This study focuses on the injection pressure in a common rail system, which is divided into a high-pressure section and a low-pressure section. A control-oriented ROI shaping (ROIs) model is developed based on the switching strategy between high and low injection pressure. Three types of ROI were generated, namely ROIB (conventional ROI), boot-ROI (low followed by high injection pressure), and anti-boot-ROI (high followed by low injection pressure) respectively. The 1-D and 3-D numerical simulations are conducted to analyze the impact of the shaped ROI on combustion and emissions for steady condition and transient condition. In terms of overall results, boot-ROI shows significant advantage among the three types of ROI. For the steady condition, the boot-ROI was able to increase the IMEP (indicated mean effective pressure) (1.57 bar) at high load conditions with almost unchanged NOx emission. For low load conditions with delayed SOI (start of injection), the exhaust temperature is close to that of the ROIB with a reduction of 0.51 g/kW·h in NOx emissions. For transient condition, the boot-ROI also shows its advantage. It was found to improve the BSFC (brake specific fuel consumption) with almost unchanged NOx emission during load-down process. And in load-up process, the BSFC and soot emission also could be improved with slightly increase in NOx emission through advance of SOI when boot-ROI was adopted. The one-dimensional model using boot-ROI reduces fuel consumption by 2 g/kW·h in experiment with WHTC cycles, with slightly higher soot emission and similar NOx emission.
The Psychological Symptoms and Their Relationship to the Quality of Life Among Dementia Patients Caregivers
Authors: Baniah Lafee Alzaben Mamduh , Suhail Mousa Shawaqfeh Baha’
Published: April 2024

The study aims to identify psychological symptoms (depression and anxiety) and their relationship to the quality of life among dementia patients’ caregivers, and whether there are differences in the level of each of them due to the gender variable. The study follows the correlational approach, with a sample of 174 dementia patients’ caregivers. To pursue the analysis, the study uses 3 measurement tools: anxiety, depression, and quality of life. The results show that the level of depression, anxiety, and quality of life among dementia patients’ caregivers is moderate. It also finds that there is a positive relationship between anxiety and depression, and there is a negative relationship between quality of life and anxiety and depression. There are no differences in the level of depression and anxiety due to gender, as the study finds female caregivers to have a higher level of quality of life.
Lessons in Legacies: Treatment Plant Expansion Under the Clean Water Act
Authors: Solis Miriam
Published: April 2024

The US Clean Water Act of 1972 required cities to build secondary wastewater treatment plant capacity to improve the environment and protect public health. The expansion of the Southeast Pollution Control Plant in San Francisco’s Bayview-Hunters Point, a historically Black neighborhood, illustrates how planners employed rational-comprehensive approaches as the bases for their decision-making, worsening the community’s environmental burdens. This occurred even as the community used recently adopted environmental policy frameworks to mitigate the plant’s consequences. The Clean Water Act should be evaluated on clean water objectives and in terms of how communities were harmed to achieve these environmental goals.
The Game-Like Experience of Virtual Reality Art: Sensational Players and Critical Audiences
Authors: Zhao Xinyang
Published: April 2024

This article delves into why audiences perceive virtual reality (VR) art as a game-like experience and how it impacts audiences’ reception of culture by examining two VR art pieces and their respective audience responses in focus group discussions. Through qualitative analysis, two factors are identified: the cognitive association of VR with gaming due to audiences’ preconceptions about VR, and the immersive environment of VR creating the “magic circle” that fosters the sense of play. The study argues that the intersection of VR and art generates the affordance allowing audiences to “play” with culture. However, the “not-serious” feature of play in VR may work against the norms and mores of a specific culture in the real world, especially when it relates to religious or ethnic culture. This article sheds light on the implications of the game-like experience in VR for creating VR applications beyond gaming, particularly in art and cultural heritage.
Different Ways of Being, Doing and Telling in Qualitative Research: Lessons From d/Deafblind Studies
Authors: Watharow Annmaree , Wayland Sarah
Published: April 2024

Traditional qualitative inquiry research methods exhort us to look for the ‘good’ story tellers who use metaphors to describe their experiences, emotions, and events. This privileges abled-bodied individuals, meaning that without full individual accessibility for people with disability is not achieved. The objective of this paper is to present a case study on inclusion of research participants who live with deafblindness. This case study posits where qualitative story telling spaces currently are; whose voices occupy these narratives; what is said and how it is said: and the performative aspects of the qualitative inquiry currently. Research including people with disability is reflected in the evidence base, however the question that if qualitative methods don’t seek to explore and understand these differences, epistemic injustices will be perpetrated. The case study reflects on a research project whose methodology sought to solicit hospital experiences for those living with deafblindness. The Australian study of 18 deafblind participants with wide ranging communication needs, shared in-depth narrative inquiry stories told in: ‘snapshots’ of moments of disempowerment; through sign and vibrotactile communication; usage of the strong verb with metaphor rarely present except to exclusively describe instances of dehumanisation. Narrative inquiry method when used with people who are deafblind is predominately chaotic with some tense instability for non-signing participants. Emphasis is via repetition, altered pitch and expletives. Touch centricity is fundamental. Dissonance is evident between words used and stories told. The thematic analysis identified a need to reflect epistemically across the creation of any qualitative project from beginning to end, focussing on what is being said and how it is being said or signed or felt. The conclusion of the paper provides a roadmap for future projects to ensure improvements in the enhancing of awareness of different ways of being, doing and telling in qualitative research methods.
Xhafer Deva: Nationalism, Collaboration and Mass Murder in Pursuit of a ‘Greater Albanian’ State
Authors: Zaugg Franziska
Published: April 2024

Xhafer Deva is one of the most notorious figures in the history of World War II in Kosovo and ‘Greater Albania’. As Minister of the Interior of the ‘Greater Albanian’ state and a Nazi collaborator, he was responsible for the assassination, deportation and expulsion of countless Serbs. At the same time, he fought for the integration of Kosovo into Albania. As such, notwithstanding the mass atrocities for which he is responsible, he is still revered in nationalist circles to this day. In this contribution, Xhafer Deva, a controversial public figure, will be examined and presented against the backdrop of the shifting empires and loyalties during the end of the 19th and the first half of the 20th century.
The 3 + 3 design in dose-finding studies with small sample sizes: Pitfalls and possible remedies
Authors: Chiuzan Cody , Dehbi Hakim-Moulay
Published: April 2024

In the last few years, numerous novel designs have been proposed to improve the efficiency and accuracy of phase I trials to identify the maximum-tolerated dose (MTD) or the optimal biological dose (OBD) for noncytotoxic agents. However, the conventional 3+3 approach, known for its and poor performance, continues to be an attractive choice for many trials despite these alternative suggestions. The article seeks to underscore the importance of moving beyond the 3+3 design by highlighting a different key element in trial design: the estimation of sample size and its crucial role in predicting toxicity and determining the MTD. We use simulation studies to compare the performance of the most used phase I approaches: 3+3, Continual Reassessment Method (CRM), Keyboard and Bayesian Optimal Interval (BOIN) designs regarding three key operating characteristics: the percentage of correct selection of the true MTD, the average number of patients allocated per dose level, and the average total sample size. The simulation results consistently show that the 3+3 algorithm underperforms in comparison to model-based and model-assisted designs across all scenarios and metrics. The 3+3 method yields significantly lower (up to three times) probabilities in identifying the correct MTD, often selecting doses one or even two levels below the actual MTD. The 3+3 design allocates significantly fewer patients at the true MTD, assigns higher numbers to lower dose levels, and rarely explores doses above the target dose-limiting toxicity (DLT) rate. The overall performance of the 3+3 method is suboptimal, with a high level of unexplained uncertainty and significant implications for accurately determining the MTD. While the primary focus of the article is to demonstrate the limitations of the 3+3 algorithm, the question remains about the preferred alternative approach. The intention is not to definitively recommend one model-based or model-assisted method over others, as their performance can vary based on parameters and model specifications. However, the presented results indicate that the CRM, Keyboard, and BOIN designs consistently outperform the 3+3 and offer improved efficiency and precision in determining the MTD, which is crucial in early-phase clinical trials.
Let’s do it: Response times in Mental Paper Folding and its execution
Authors: Dahm Stephan Frederic , Sachse Pierre
Published: April 2024

Action imagery is the ability to mentally simulate the execution of an action without physically performing it. Action imagery is assumed to rely at least partly on similar mechanisms as action execution. Therefore, we expected that imagery and execution durations would be constrained by the number of folds in a Paper Folding Task. Analogously, individual differences in execution durations were expected to be reflected in imagery durations. Twenty-eight participants performed two imagery conditions (computer vs. paper) and one execution condition (paper) where two-dimensional grids of a three-dimensional cube were (mentally) folded to determine whether two selected edges overlapped or not. As expected, imagery performance and execution performance were strongly correlated and decreased with the number of folds. Further, the number of folds influenced imagery durations even more than execution durations. This may be due to the additional cognitive load in imagery that emerges when tracking the folds to follow up with the next ones. The results indicate that Mental Paper Folding predominantly involves dynamic visual representations that are not functionally associated with one’s own movements as in action imagery.
Postoperative cognitive dysfunction: Review of pathophysiology, diagnostics and preventive strategies
Authors: Nešković Nenad , Budrovac Dino , Kristek Gordana , Kovačić Borna , Škiljić Sonja
Published: April 2024

Postoperative cognitive impairment is a common disorder after major surgery. Advances in medicine and treatment have resulted in an increasingly ageing population undergoing major surgical procedures. Since age is the most important risk factor for postoperative cognitive decline, it is not surprising that impairment of cognitive functions after surgery was recorded in almost a third of elderly patients. Postoperative cognitive dysfunction is part of the spectrum of postoperative cognitive impairment and researchers often confuse it with postoperative delirium and delayed neurocognitive recovery. This is the cause of great differences in the results of research that is focused on the incidence and possible prevention of postoperative cognitive dysfunction. In this review, we focused on current recommendations for a uniform nomenclature of postoperative cognitive impairment and diagnosis of postoperative cognitive dysfunction, the presumed pathophysiology of postoperative cognitive dysfunction and recommendations for its treatment and possible prevention strategies.
How diabetes forum-users complain about others’ expectations: Troubles-telling and troubles-receiving
Authors: De Cock Barbara , Antaki Charles
Published: April 2024

This article offers a qualitative analysis of two instances of troubles-telling threads on a diabetes forum, with a specific focus on how these instances contribute to constructing a way to manage others’ expectations concerning how persons diagnosed with diabetes control their condition. From the perspective of conversation analysis and discursive psychology, this article shows some recurrent features of both troubles-telling (namely announcement, stake inoculation and self-deprecation) and of troubles-receiving (namely appreciation, second stories, escalation). Our analysis furthermore shows how inadequate expectations from family members are judged differently from those of health professionals. The latter are judged more harshly for what seems a lack of professional competence, whereas the former are more easily pardoned but pose a particular challenge in that patients do not wish to remove these persons from their lives. Through this analysis, we contribute to showing a particularly important function of patient fora, namely allowing patients to tell troubles about others’ expectations and to receive support and advice for these circumstances that put a heavy emotional burden.
International Migration Framing in the Global Times (2012–2022): Constructing Identity Narrative About the Self and the Other
Authors: Soboleva Elena
Published: April 2024

This article addresses a research gap in the studies of international migration discourse in China's mass media. The focus on the Global Times, a Chinese Communist Party-owned commercialised newspaper famous for its nationalist discourse, elucidates how news about this global issue is used to construct China's identity narrative. The empirical part includes the analysis of the data spanning a decade (2012–2022) collected from the Global Times. It is studied with the help of computational text analysis tools, including topic modelling that is used to identify frames in the coverage of international migration. The analysis reveals that the Global Times devotes disproportionate attention to migration-related political, security, and socio-economic problems in the West, reproducing elements of the mainstream discourse in the Western media. Such overrepresentation, coupled with the selective coverage of China's own experience with international migration is used to emphasise the weaknesses of the Other in contrast to the stable Self.
Sustainability Within the HRD Field: A Systematic Review
Authors: Lee Sumi , Han Seung-hyun , Oh Jihye
Published: April 2024

Promoting sustainability creates environments for thriving while conserving resources for generations to come. Implementing sustainability practices has been increasingly emphasized, as businesses are required to go beyond their organizational boundaries and improve performance. Despite the intense interest in sustainability, its research has rarely been investigated and synthesized within the current knowledge base in the HRD field. Therefore, we aim to systematically analyze recent articles on sustainability and its relevance to HRD. We conducted a systematic review of the literature in this by following the PRISMA guidelines, and this resulted in a set of 59 articles. Our review identified several impending issues of sustainability, such as a lack of definitions, constructs, and empirical investigation of sustainability. Based on the findings, we discussed them from the recent conversations on sustainability and emphasized the role of HRD in how organizations should be based on sustainability and how to promote sustainability through integrated learning. In addition, this review delved into key strategies to foster sustainability initiatives and discussed implications for HRD practice and research.
Can Human Growth Hormone Accelerate Tendon and Ligament Injury Recovery?
Authors: Baumgarten Keith M. , Sandhurst Eric S. , Sun Hongli
Published: April 2024

Background:

Studies involving human fibroblasts and use of human growth hormone (HGH) administration for injury recovery are limited. It is plausible that if the administration of HGH to human cells increased cellular proliferation and differentiation, then HGH might be able to assist in accelerating recovery from injury.

Hypothesis:

HGH will increase proliferation and differentiation of human tendon and ligament fibroblasts in vitro based on both a single-dose and a sustained-dose model of HGH administration.

Study Design:

Basic science cellular study.

Methods:

Human tendon and ligament tissue were harvested from 24 patients. Tissue samples were digested with type I collagenase to isolate the target cell types. HGH was administered directly to isolated cells at doses ranging from 100 pg/mL to 10 µg/mL, either in a single-dose or a sustained-dose model. Proliferation was analyzed at days 4 and 7. Differentiation of ligament and tendon fibroblasts was assessed at day 14.

Results:

Administration of a single-dose of HGH to both cell types demonstrated similar or inferior cellular proliferation compared with controls after 7 days. For the sustained-dosing model of ligament fibroblasts, only the 100 ng/mL concentration demonstrated at least statistically similar or improved proliferation compared with controls. When examining the 100 ng/mL HGH concentration with larger sample sizes, cellular proliferation was not improved over controls for any cell type for the single- or sustained-dosing models. Proliferation for tendon fibroblasts was either similar or inferior to the control group at all concentrations of HGH. There was no clear dose-response relationship demonstrating enhanced collagen production with administration of HGH to suggest it enhances injury recovery.

Conclusion:

HGH administered to human tendon and ligament fibroblasts does not appear to positively affect cellular proliferation and differentiation.

Clinical Relevance:

This study does not support the use of HGH for accelerating recovery from injury.
A cross-sectional study of resilience and well-being among nursing students in Saudi Arabia
Authors: Rayani Ahmad M , Alodhailah Abdulaziz M , Alreshidi Salman M
Published: April 2024

Objectives:

Promoting resilience and embracing healthy coping strategies can effectively assist nursing students in managing stress and enhancing their welfare. Nonetheless, a comprehensive understanding of the factors influencing their well-being and resilience, pivotal for both academic accomplishments and future career longevity, remains incomplete.

Methods:

A cross-sectional descriptive correlational design was adopted for this study. Participants comprised students enrolled in pre-registration nursing programs at both undergraduate and graduate levels. The World Health Organization-5 Well-Being Index and the 10-item Connor-Davidson Resilience Scale were utilized to assess psychological well-being and resilience, respectively.

Results:

The study involved 175 university nursing students selected through convenience sampling. On the 10-item Connor-Davidson Resilience Scale, the average score was 25.5, with undergraduate and graduate students scoring an average of 25.4 and 26.3, respectively. Nevertheless, the two groups had no statistically significant difference ( p = 0.526). Regarding perceived well-being, the average World Health Organization-5 score was 16.1, with no noticeable distinction between undergraduates and postgraduates ( p = 0.858). Notably, bivariate analysis revealed a moderate positive correlation between self-reported resilience and perceived well-being ( rp = 0.281, p = 0.001). Moreover, senior students exhibited significantly higher scores on the perceived well-being scale than junior students (17.0 vs 15.1, p = 0.010). Multivariable regression analysis also identified that self-reported resilience represents a consistent means of predicting perceived well-being (regression coefficient B = 0.22, p < 0.001).

Conclusions:

The outcomes indicate that university-based nursing students who exhibit higher levels of resilience have more positive perceptions of their well-being. Moreover, postgraduate students exhibit more significant resilience levels than undergraduate students.
Lupus enteritis as systemic lupus erythematosus main manifestation: Two case reports
Authors: Chaparro Camilo Andrés , Bernal-Macías Santiago , Muñoz Oscar Mauricio
Published: April 2024

Lupus enteritis denotes inflammation of the intestinal walls resulting from the influence of systemic lupus erythematosus. It represents a rare manifestation associated with notable morbidity and mortality, marked by nonspecific gastrointestinal symptoms. In this article, we present two cases of individuals experiencing severe gastrointestinal symptoms. They had a personal or familial history of autoimmunity with intestinal involvement consistent with the presentation of lupus enteritis. Following treatment with glucocorticoids and immunomodulators, both patients exhibited a satisfactory clinical evolution. While lupus enteritis remains an uncommon occurrence, its clinical significance is undeniable. Hence, it is imperative to maintain a high level of clinical suspicion to facilitate prompt diagnosis and treatment.
The EU Settlement Scheme: Footprints in quicksand
Authors: Juverdeanu Cristina
Published: April 2024

Part of an accelerated trend to integrate algorithms in immigration decision-making, the UK's EU Settlement Scheme relies on automated data checks as an essential and mandatory step in the application for UK residence. In this article, I engage with the literature on datafication and algorithmic accuracy to showcase algorithmic inaccuracy within borders in regard to the allocation of residence statuses and rights. I argue that, while the EUSS uses big data to create a data double of the ‘desirable’ migrant, even applicants within this category experience mismatches. Some EU+ Citizens on linear residence and career trajectories were initially offered pre-settled status and had difficulty proving their entitlement to the full status, while others, who did not qualify for settled status, obtained it nevertheless. The analysis is based on in-depth interviews with high skilled applicants, and experts on the EUSS, exposing that footprints are not evidence per se. Instead, the outcomes are decided by an opaque algorithm that is not retained and disappears as easily as footprints in quicksand.
Assessing Teacher Competencies in Public Schools of Pakistan: A Pathway for Improving the Effectiveness of Professional Development Programs for Teachers
Authors: Kalim Usama , Bibi Saira
Published: April 2024

Professional development (PD) programs are considered as essential for improving the teacher quality and performance in schools. Despite introducing several PD programs, the teachers’ quality in the public schools is a matter of concern for Pakistan. It has become a challenge for policymakers and school leaders to design PD programs which can be effective for all teachers. PD programs in Pakistan normally undertakes a standard approach without considering the strengths and weaknesses of different groups of teachers which may not address the specific needs of these groups. There is a need of structuring PD programs to make these learning opportunities more effective for teachers. Therefore, the current study evaluates the teacher competencies of different groups of teachers in Pakistan’s public schools. For that purpose, the study first identifies three key themes of teacher competencies required in 21st century from extant review of recent literature. Interview guide then is designed based on these key teacher competencies to solicit information from seven principals of public schools. The public schools were selected using the criteria of size of school and principal working experience in that school. Structured interviews been used as a medium for collecting data from the principals. All interviews were recorded and transcribed verbatim. The deductive content analysis approach was used in analyzing the data. The analytical tool used for the coding of themes was the MAXQDA software. The results highlighted certain differences in teacher competencies varying from gender to age. Female teachers and teachers who are younger in general are found to have more competencies compared to male teachers and senior teachers. The results of this study offer vital information for planning and tailoring TPD programs for teachers. These specially designed learning opportunities can be more effective for the professional development of teachers and can foster teachers’ competence.
Listening to the Voices of Mothers Who Participated in a Video Feedback Intervention for Postpartum Depression
Authors: Bon Bernard Jennifer , Moules Nancy , Tough Suzanne , Tryphonopoulos Panagiota , Letourneau Nicole
Published: April 2024

Postpartum depression (PPD) symptoms can negatively influence mother-infant interactions. Video-Feedback Interaction Guidance for Improving Interactions Between Depressed Mothers and their Infants (VID-KIDS) is a parenting intervention that allows mothers experiencing PPD symptoms to observe and improve their interactions with their infants. VID-KIDS has also positively influenced infants’ stress (cortisol) patterns. There is limited research on maternal perspectives of interventions like VID-KIDS. In this hermeneutic study, four mothers were interviewed to increase understanding of the VID-KIDS experience. Key findings included: 1) VID-KIDS provided an opportunity for mothers with PPD symptoms to positively transform their identity; 2) VID-KIDS provided a chance to witness the mother-infant relationship forming and improve maternal mental health and; 3) VID-KIDS provided a space for mothers to dialogue about their experience with PPD symptoms authentically. VID-KIDS promoted healing from PPD as mothers experienced a transformation in how they perceived themselves and their relationships with their infants.