bluuebunny/crossref_metadata_2025 huggingface dataset:
Toxicity and Binding Assessment of Pararosaniline with Biological Proteins: Myoglobin and Hemoglobin (A Computational Approach)
Authors: - Ritika Singh , - Nibedita Mahato , - Dr. Prateek Pandya
Published: January 2025

This study explores the intricate molecular interactions between pararosaniline (BR9)
and crucial proteins, myoglobin (MB) and hemoglobin (HB), employing advanced
computational docking methodologies. The study prepares a protein structure by
removing the solvent molecules and irrelevant ligands, ensuring a refined
environment for accurate docking stimulations. Additionally, the ligand structure of
pararosaniline undergoes optimization to facilitate compatibility with docking
software utilizing CB Dock and Seam Dock software. Docking simulations are
conducted carefully, with defined parameters allowing for the exploration of various
binding modes and prediction of binding affinities. The comparative analysis of two
docking platforms serves to enhance the reliability of the results. Furthermore, the
study integrates the toxicity predictions of pararosaniline using computational tools
to discern potential biological implications. By intervening in structural biology,
computational chemistry, and toxicology, this comprehensive approach offers
profound insight into intricate molecular dynamics and potential toxicological
ramifications of pararosaniline interactions with myoglobin and hemoglobin.
Secure Artificial Intelligence (SAI): A Dual-layer defence model against prompt injection and prompt poisoning attacks
Authors: - Hitika Teckani , - Devansh Pandya , - Harshita Makwana
Published: January 2025

Secure Artificial Intelligence (SAI): A Dual-layer defence model against prompt injection and prompt poisoning attacks.
Keywords— Large Language Model, Secure Artificial Intelligence, Artificial Intelligence, Prompt Injection, AI security.
Abstract— Artificial Intelligence (AI) is deeply embedded in sectors handling sensitive information and mission-critical operations, and safeguarding these systems has become paramount. This paper introduces a novel dual-layer defence system termed Secure Artificial Intelligence (SAI), designed to mitigate risks associated with prompt injections and prompt poisoning attacks. Using two Large Language Models (LLMs) in a sequential setup “SAI”– a “Guard” model for initial input prompt classification which effectively filters out adversarial inputs to protect the AI system and a primary response model that responds to the user’s queries. Through rigorous testing, SAI has shown resilience in preventing malicious prompts from compromising AI responses, thereby significantly advancing AI security. This paper thoroughly examines SAI’s architecture, methodology, and performance, addressing the growing demand for secure and adversarial-resistant AI systems.
Effect of Aquatic Pollution on Fish in Libya: A Review
Authors: - Mona I. Saad , - , Huwaida M. Doma , - Issam A. Alfaghi , - Amani Fitori
Published: January 2025

Aquatic pollution has a serious negative influence on Libya's vast coastline, endangering both human health and marine ecosystems. This paper highlights the main contaminants, their sources, and the biological effects of water pollution on fish species in Libyan waters. Heavy metals (mercury, lead, arsenic, and cadmium), microplastics, polycyclic aromatic hydrocarbons (PAHs), and artificial detergents such as sodium lauryl sulphate (SLS) are important contaminants. Industrial discharges, untreated wastewater, petrochemical operations, and agricultural runoff are the sources of these contaminants.They cause genetic harm, physiological changes, and ecotoxicological concerns in fish species, which may cause cancer in humans who consume them. Food security and marine biodiversity are at risk because elevated pollutant levels frequently surpass global safety criteria established by the FAO and WHO. In order to protect Libya's marine ecosystems and coastal communities, this report emphasises the urgent need for stronger legislation, improved environmental monitoring, and efficient mitigation strategies.
The Influence of Parental Engagement, Parenting Approach on Scholarly Success, and Emotional Intelligence among Adolescents.
Authors: - Deshmukh Milind Babaso
Published: January 2025

“This study examines The Influence of Parental Engagement, Parenting Approach on Scholarly Success, and Emotional Intelligence among Adolescents. The research is set in the context of modern societal trends, where both parents often engage in full-time jobs, potentially reducing their involvement in their children's education and extracurricular activities. A sample of 100 students aged 13–19 years from Mahatma Phule Vidyalaya, Urun-Islampur, Sangli was analyzed using standardized tools, including the Children’s Perception of Parenting Scale (CPPS), Emotional Intelligence Scale, and the Parental Involvement Scale (TPIS). Key findings include a significant influence of parenting style on academic achievement (F = 42.14, p < 0.05), with autocratic parenting identified as most impactful. However, parenting style showed no significant effect on emotional intelligence (F = 0.12, p = 0.73). Similarly, no significant relationships were found between parenting involvement and either academic achievement (F = 1.04, p = 0.392) or emotional intelligence (F = 0.6, p = 0.666). The study highlights the nuanced effects of parenting practices on adolescent development while identifying limitations in sample size and randomness, suggesting future research directions. These include larger, more diverse samples and further exploration of other influencing variables.”
“Drowning Journalism”- A Qualitative examination of problems faced by journalists and aspiring journalist in Jamshedpur
Authors: - Abhirup Bhadra
Published: January 2025

This research paper explores the challenges faced by working journalists and students who want to pursue their career in journalism in Jamshedpur, a city known for its industrial landscape and diverse community. Using unstructured interviews with 10 senior journalists from local newspapers and insights from the students enrolled in professional degree, this study delves into the professional, ethical, and socio-economic difficulties they encounter. The findings highlight the interplay of resource constraints, editorial pressures, safety concerns, and evolving public expectations in shaping the journalism profession in the region.
Fragmented Identities and Cultural Reflections in Indian Some Women’s Writing
Authors: - MR S ANANDAN , - Dr. PRASOON TRIPATHI
Published: January 2025

This paper focuses on the study of emerging, potent voices of selected women writers, Shashi Deshpande, Jhumpa Lahiri and Chitra Banerjee Divakaruni. Belonging to India gives these writers certain common ethical values and identity, while the differences between them result from the fact that living abroad widens the mental horizons of Indian women. These women are no doubt conditioned by the Indian upbringing but have risen above the traditional constraints. This paper attempts to describe the crisis and solution to ethical values and identity from India living in in the layers of selected works of Indian women writers. There is constant interplay of nostalgia and reality in their works. At a deeper level they show a conflict between tradition and modernity. The trials and tribulations and the struggle to maintain the modern values and to carve out an identity of their own in the new and ostensibly stifling environment of her protagonists makes them a feminist.
An Analysis of the Social and Economic Impact of Lay-Off in Industrial Sector with Reference to Current Scenario.
Authors: - Praveen Kumar Pandey
Published: January 2025

ABSTRACT
This study analyzes the social and economic impact of layoffs in the industrial sector, with a particular focus on the current scenario. It endeavours to ascertain the social-economic impacts of an unanticipated and involuntary layoff of employees, analyses the impact of the legislation in this context, and explores the measures implemented by those who have lost their jobs as a result of layoffs. The several social scientists and psychologists have studied the effects or implications of losing one's job. Their findings indicate that lay-offs traumatize both the lives of the individual and their loved ones. Every member of society is negatively impacted by retrenchment, including the organization, the company, and the fortunate individuals who survive. Lay-offs causes a rapid and permanent crisis. It maintains a focus on the socio-economic impacts but the narrower scope is to a specific industry, which could provide more targeted insights. Additionally, it can explore both short-term and long-term effects on workers, families, and communities, into strategies for mitigating the negative consequences of lay-offs. The industrial sector, often viewed as a pillar of economic stability and growth, has experienced significant disruptions, leading to workforce reductions. The research explores the causes behind these lay-off, such as automation, economic downturns, and global market competition, and investigates their repercussions on both the employees and the broader economy. Socially, layoffs result in increased unemployment, mental health challenges, and family instability, while economically, they contribute to reduced consumer spending, lower productivity, and slower economic growth. This study also assesses the role of government policies, corporate social responsibility (CSR) practices, and reskilling initiatives in mitigating the negative impacts of layoffs. By using qualitative and quantitative methods, including case studies and employee surveys. This research aims to provide a comprehensive understanding of how lay-offs affect both individuals and the industrial sector as a whole, offering recommendations for better workforce management and support systems in times of crisis.
Oral Bioequivalence Study Of Dapagliflozin 10 Mg And Rosuvastatin 20 Mg Tablet In Healthy Indian Subjects Under Fasting Conditions
Authors: - Rahul Kapse , - Swarali Bhakare , - Deepak Bagde , - Prashant Kumthekar , - Mihir Upadhyay , - Vishwas Pukale
Published: January 2025

The objective to conduct this study is to compare the rate and extent of absorption and also to monitor the safety and tolerability of a single dose of Dapagliflozin 10 mg and Rosuvastatin 20 mg Tablets using Open label, balanced, randomized single-dose, two-treatment, two-sequence, two-period two-way Crossover design in 24 Healthy, Adult, Human Subjects Under Fasting Conditions. All subjects were dosed with the one tablet of Test product (T): Dapagliflozin 10 mg and Rosuvastatin 20 mg Tablet or reference product (R): Forxiga® 10 mg (Dapagliflozin 10 mg Tablets) and Rosulip 20 (Rosuvastatin 20 mg Tablets orally while in sitting position with 240 mL of 20% aqueous glucose solution as per the randomization schedule at ambient temperature. The LC-MS/MS method was developed at Bion Clinicals Pvt. Ltd., Pune, India to determine Plasma concentrations of Dapagliflozin and Rosuvastatin.
The result showed ratios of geometric least squares means of the test product (T) and reference product (R) for the Ln-transformed pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞ of Dapagliflozin were found to be 93.21%, 97.09% and 96.12% respectively and for Rosuvastatin were found to be 101.29%, 100.91% and 99.39%.
The 90% confidence intervals for the ratios of geometric least squares means for the Ln-transformed pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞ of Dapagliflozin were found to be 84.38% -102.97%, 93.45% -100.88% and 92.60%-99.78% respectively.
The 90% confidence intervals for the ratios of geometric least squares means for the Ln-transformed pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞ of Rosuvastatin were found to be 91.53%-112.09%, 91.39%-111.43% and 88.16%-112.04% respectively.
In conclusion, the 90% confidence intervals of the differences of least squares means for the Ln-transformed pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞ of Dapagliflozin and Rosuvastatin were within the bioequivalence acceptance limits of 80.00 - 125.00% and thus the test product (T): Dapagliflozin 10 mg and Rosuvastatin 20 mg Tablet and reference product (R): Forxiga® 10 mg (Dapagliflozin 10 mg Tablets) and Rosulip 20 (Rosuvastatin 20 mg Tablets) were found bioequivalent with respect to rate and extent of absorption. The Dapagliflozin 10 mg and Rosuvastatin 20 mg oral dose was well tolerated and was found safe.
The Psychological Impact of Meditation Practices: A Systematic Review on Anger Management in Workplace Settings
Authors: - SUNIL SUNDERDAS MOTIRAMANI , - MEHULKUMAR SURENDRABHAI PATEL
Published: January 2025

This systematic review explores the psychological impact of meditation practices on anger management in workplace settings. By synthesizing data from multiple studies, this review aims to evaluate the effectiveness of various meditation techniques in reducing anger and enhancing emotional regulation among employees. The review includes a comprehensive analysis of randomized controlled trials, observational studies, and qualitative research, focusing on outcomes such as self-reported anger levels, behavioral changes, and physiological markers of stress. Preliminary findings suggest that meditation practices, particularly mindfulness-based interventions, can significantly reduce anger and improve overall emotional well-being in workplace environments. This review highlights the potential of meditation as a cost-effective and non-pharmacological approach to anger management, with implications for organizational policies and employee mental health programs.
Workplace stress and anger are significant challenges that affect employee well-being and organizational productivity. Meditation practices, particularly those rooted in mindfulness and spiritual traditions, have gained attention for their potential to mitigate these issues. This systematic review examines the psychological impact of meditation practices, with a focus on their effectiveness in anger management within workplace settings. Drawing on evidence from peer-reviewed studies, the review explores the underlying mechanisms through which meditation influences emotional regulation, stress response, and interpersonal behavior.
Special emphasis is placed on practices like meditation, mindfulness-based stress reduction (MBSR), and transcendental meditation, assessing their role in fostering emotional stability and resilience among employees. Findings indicate that meditation practices significantly reduce anger levels by enhancing self-awareness, promoting cognitive reappraisal, and reducing physiological markers of stress. The review also highlights the organizational benefits of integrating meditation programs, including improved workplace harmony, employee engagement, and mental health outcomes.
The Synergy of Generative AI and Big Data for Financial Risk: Review of Recent Developments
Authors: - Satyadhar Joshi
Published: January 2025

This paper presents a comprehensive review of the latest development in Generative AI and Big Data with application in Finance. 2025 is the year of Agentic AI, marking a pivotal shift in generative AI (Gen AI) and its integration with big data. This paper explores the synergies between Gen AI and big data, particularly in financial risk management, proposing strategies for deeper integration. By citing the latest white papers and focusing on developments over the past two years, we expand the scope of research in this transformative domain. Recent advancements in Gen AI, such as GPT-4, VAE-GANs, and explainable AI architectures, demonstrate significant improvements, including 25–40% gains in workflow efficiency and 18–30% reductions in error margins for financial and enterprise systems (based on current literature). We segment these developments to identify potential applications in market and credit risk, while addressing challenges such as the lack of universal Python full-stack architectures. To bridge this gap, we propose recommendations for seamless communication between Gen AI and big data systems, enabling scalable solutions and actionable insights. This paper underscores the role of Gen AI in transforming big data into operational excellence, setting the stage for future innovations in financial and enterprise analytics.
The Impact of the Gig Economy on Traditional Labour Laws in Maharashtra, India
Authors: - Kumar Dinesh Warghade , - Taherali Bakir Slatewala , - Ramesh Paras Gupta
Published: January 2025

The emergence of the gig economy in India, backed by technological advancements and changing societal norms, has significantly altered the landscape of labour markets. This paper examines the impact of the gig economy on traditional labour laws in Maharashtra, a state experiencing a rapid rise in gig work. It explores the challenges posed by this shift, evaluates the gap between existing labour laws and the realities of gig work, and proposes reforms aimed at protecting gig workers while fostering economic growth.
CYBER SECURITY
Authors: - Dr.chandrika G
Published: January 2025

Cyber security plays a vigorous role in the area of information technology. Safeguarding the information has become an enormous problem in the current day. The cybersecurity main thing that originates in mind is 'cyber crimes' which are aggregate colossally daily. Different governments and organizations are taking numerous measures to keep these cyber wrongdoings. Other than different measures cybersecurity is as yet a significant worry to many. This paper mostly emphasizes on cyber security and cyber terrorism. The significant trends of cybersecurity and the consequences of cybersecurity are discussed in it. The cyber-terrorism could make associations lose billions of dollars in the region of organizations. The paper also explains the components of cyberterrorism and its motivation of it. Two case studies related to cybersecurity are also provided in this paper. Some solutions for cyber security and cyber terrorism also explain in it.
Comparative Assessment on Physiological and Psychological Variables among Different Format of Soccer Games
Authors: - Limon Kumar Saha , - Manoj Kumar Murmu
Published: January 2025

The goal of this analysis was to compare among small sided different format of soccer players on selected Physiological parameter and psychological variable from different club of West Bengal. Thirty subjects (N=30) having age range from 16 to 19 years, (average of their ages 17.57±1.43 years, average of their heights 171.18±5.16 cm, average of their body weights 68.15±4.21 kg and average of their sports experiences 4 years) who must have participated at different format of soccer games in different clubs in West Bengal voluntarily participated in this study. The physiological capacity measurements of players in this study were determined by Vo2 max test. The psychological variable was measured by Self-esteem scale. “F” test statistical procedure was taken and analysis of variance was set at 0.05% level of confidence. In order to find out the comparison of selected variables in different formats among soccer players from different clubs, the One-way Analysis of Variance (ANOVA) was applied.In comparison of Vo2 max and Self-esteem level, it was statistically found that there was no significant difference among different format of Soccer players (P>0,05).
Social Engineering 2.0 Deepfake and Deep Learning-based Cyber-attacks (Phishing)
Authors: - Siva Krishna Jampani
Published: January 2025

This research paper examines the emerging risk of deepfake phishing, or modern social engineering, where deep learning techniques are used to produce realistic fake media for cyberattacks. The paper investigates the topic of deepfakes: voice and video manipulation which have become widespread tools to mislead the target audiences and bring severe financial and organizational losses. The study relies on secondary sources and provides trend analysis, case and quantitative data to demonstrate increase in deepfake phishing attacks in the finance, healthcare and technology sectors. By considering sectoral data, the paper determines the biggest focused areas, which stated, finance and healthcare have the highest proportion of the financial damages. The present research also explores the development in the technology of deepfake and explains how the technology has improved the authenticity of fake videos and audio by providing examples of how these technologies have advanced from simple imitations to near-photorealistic replicas of real voices and faces. What consequences do have this progression for the rate of successful phishing attacks? The answer is quite serious – with this progression, the attackers can act more freely as they do not need to overcome conventional security barriers. Finally, the paper urges people to fight these risks using AI tools for time-independent deep fake detection, stricter guidelines and specific informative training for employees for such shiny attacks. Through exploring the current state of deepfake phishing as a threat, the work underscores the importance of continuing caution and development in cyber defence. The research indicates that to address the threats posed by deepfake phishing one needs to employ both, developed technological solutions and actively maintained organizational shields.
Market Dynamics and Consumer Preferences for Organic Rice Purchase in Central Java and Yogyakarta, Indonesia
Authors: Rozaki Zuhud , Alifah Salsabilla , Rahmawati Nur , Triyono  , Al Hadi Salsabila Salma , Ardila Riska Aula , Pamungkas Himawan Wahyu , Fathurrohman Yusuf Enril
Published: January 2025

The production and consumption of organic rice in Indonesia continue to increase along with the growing public awareness of the importance of healthy eating habits and environmental conservation efforts. Consumers in Central Java and Yogyakarta increasingly favor organic rice, prioritizing health and product quality. This has led to increased demand and can also motivate farmers to increase organic rice production to meet the ever-growing market needs. This study analyzes the market dynamics and consumer preferences for organic rice in Central Java and Yogyakarta. The research employed a quantitative descriptive approach, utilizing the 4P marketing mix (product, price, place, promotion) and a Likert scale to measure consumer preferences. Sampling was conducted through proportional stratified random sampling from five regencies, with 310 respondents. The results show that promotion is the most significant factor influencing consumer purchasing decisions, with a relative importance of 30.289%. The primary factors driving consumer preferences for organic rice are health benefits and product quality. Although organic rice is priced higher than conventional rice, consumers tend to choose it due to its health and sustainability benefits. However, uneven distribution of organic rice and price fluctuations caused by high production costs and climate factors pose major challenges. The study suggests more intensive promotional strategies, improved market accessibility, and subsidy policies to support farmers’ production costs. By understanding market dynamics and consumer preferences, this research provides critical insights for stakeholders to design more effective policies and marketing strategies while supporting sustainable agriculture in Indonesia.
Dificuldades nos processos de ensino e de aprendizagem de Mudanças de Coordenadas: uma análise no contexto do Cálculo Integral
Authors: Silva Pedro Aurélio Cardoso da , Mota Janine Freitas
Published: January 2025

The study's axis of discussion was the difficulties faced by teachers and students in teaching and learning Coordinate Changes. With a qualitative approach, a Systematic Literature Review was carried out based on a selection of theses, dissertations and articles on the topic. Eleven academic productions reached the final stage of selection, with the general objective of analyzing the use of Digital Technologies in teaching Coordinate Changes in Multiple Integrals, in theses, dissertations and scientific articles, focusing on the difficulties reported about the processes of teaching and learning. With the analysis, common difficulties in learning Integral Calculus were identified, such as the difficulty in visualizing and understanding the integration processes, and the lack of contextualized exercises. Studies indicate that digital tools such as GeoGebra helped to overcome some of these difficulties, providing better visualization of mathematical objects.
Kerja sama Perpustakaan IKOPIN dan Perpustakaan Universitas Al-Mas'oem dalam Memenuhi Kebutuhan Informasi Pengguna
Authors: Rashifa Saffana , Rukmana Evi Nursanti
Published: January 2025

IKOPIN and Al-Mas'oem University Libraries are university libraries that play an important role in supporting implementation of  Tri-Dharma of higher education. In order to fulfill this function, it is impossible for university libraries to act independently. Cooperation is needed in fulfillment, improvement, development, procurement and promotion of the services provided by the library to its users. This research aims to see how cooperation and impact of organizational structure in the cooperation carried out by IKOPIN Library and Al-Mas'oem University in meeting the information needs of users. This research has been conducted using a qualitative approach through a case study research instrument through observation, interviews, and literature studies. The process is carried out with the existence of MoA, MoU and discussions related to the collaboration. The impact of the cooperation between IKOPIN Library and Al-Mas'oem University can be seen in the improvement of quality and services that mainly affect users and librarians through cross borrowing services, librarian comparative studies, information exchange and joint collection procurement. In practice, the cooperation between the two libraries has not been successful. The unsuccessful cooperation between the two libraries is caused by many things, but the most likely is the inappropriate organizational structure implemented.
Perkembangan Penelitian Penggunaan Artificial Intelligence di Perpustakaan Berbasis Data Scopus
Authors: Tupan Tupan
Published: January 2025

This study aims to analyze the development of AI use in libraries with bibliometric methods based on Scopus data. The study uses bibliometric analysis methods. Data were collected from the Scopus database using the keywords (Artificial intelligence OR AI) AND (Library" OR Libraries)) AND (Limit-To ( Subjec Area, "Soci" ) ) AND ( Limit-To ( Language , "English" ) ) AND ( Limit-To ( Doc Type , "ar" ) ). The data were analyzed using the R-biblioshiny   and VOSviewer tools. The results of the study show that the trend of research on the use of artificial intelligence in libraries has increased significantly since 2020. The most widely used keywords in research on the use of artificial intelligence in libraries are artificial intelligence, machine learning academic libraries, libraries, ChatGPT, AI, library services, natural language processing, education information literacy and chatbots. The most productive main journals are Library Hi Tech News, Journal of Chemical Information and Modeling, Journal of Academic Librarianship, Library Hi Tech, Library Philosophy and Practice, and Electronic Library. The latest trending topics are AI literacy, electronic data interchange, intelligent libraries, library technologies, robotics in libraries, smart services, chatbots, ChatGPT, humanoid robot, large language models, library maching, library operations, library technology, openrefine, user experience, and research support. The results of this study can help libraries understand the direction of AI technology development to improve services.
Potensi Industri Pangan dalam Pengembangan Pariwisata Bromo: Persepsi Penduduk Desa Wonokitri
Authors:   Food Technology Program, Universitas Ciputra Surabaya, Krisbianto Oki , Minantyo Hari ,   Tourism-Culinary Business, Universitas Ciputra Surabaya, Sahertian Juliuska ,   Tourism-Culinary Business, Universitas Ciputra Surabaya
Published: January 2025

Pembangunan pariwisata di kawasan Bromo berpotensi merusak budaya Tengger akibat masuknya budaya asing yang dibawa wisatawan, seperti tergilasnya pangan warisan budaya Tengger oleh jenis makanan yang lebih populer dikenal wisatawan. Peran industri pangan penting untuk mendukung citra pangan warisan budaya Tengger, antara lain meningkatkan kapasitas produksi, sanitasi, keamanan, standar kualitas, umur simpan, dan penanganan limbah makanan. Permasalahan yang dihadapi adalah kesiapan sumber daya manusia hingga teknologi masyarakat Tengger serta seberapa jauh kesediaan masyarakat Tengger dalam menyerap perkembangan zaman tanpa mengubah adat budaya tradisional mereka. Penelitian ini bertujuan untuk mengetahui persepsi masyarakat Tengger yang tinggal di Desa Wonokitri, Pasuruan, terhadap potensi pengembangan industri pangan di sana. Metode penelitian yang dipilih adalah penelitian kuantitatif secara sampling kuota terhadap 400 orang penduduk Desa Wonokitri di Pasuruan dengan menggunakan kuesioner. Ditemukan bahwa meskipun mayoritas responden berpendapat bahwa industri pangan sangat mungkin untuk didirikan di Wonokitri, kurangnya minat penduduk dan kurangnya keterampilan menjadi penghambat yang paling utama. Selain itu, kurang dari separuh responden terjangkau penyuluhan dan kurang dari seperempatnya terjangkau bantuan modal pemerintah. Temuan penelitian ini dapat dimanfaatkan untuk pengembangan pariwisata Bromo yang berkelanjutan, baik untuk konservasi alam maupun konservasi budaya Tengger.
Predicting Postoperative Mortality in Head Injury Patients: Evaluating the Accuracy of Rotterdam Score
Authors: Fadhli Aufar Kasyfi  , Agung Muda Patih  , Erial Bahar
Published: January 2025

Introduction: Head injury remains a leading cause of mortality and morbidity globally, necessitating accurate prognostic tools to guide clinical decision-making and inform patient outcomes. Rotterdam Score, a computed tomography (CT)-based scoring system, has shown promise in predicting mortality in head injury patients. This study aimed to evaluate the accuracy of the Rotterdam Score in predicting postoperative mortality in head injury patients undergoing surgery.
Methods: A retrospective analysis was conducted on 56 head injury patients who underwent surgery at Dr. Mohammad Hoesin General Hospital, Palembang, between December 2023 and November 2024. Patient demographics, clinical characteristics, and CT scan findings were collected. Rotterdam Score was calculated for each patient, and its accuracy in predicting postoperative mortality was assessed using receiver operating characteristic (ROC) curve analysis.
Results: The study cohort comprised 37 (66.1%) males and 19 (33.9%) females, with a mean age of 31.8 ± 21.6 years. Mild head injury was the most common Glasgow Coma Scale (GCS) classification (42.9%). The overall mortality rate was 17.8%. ROC curve analysis revealed an area under the curve (AUC) of 0.953 for the Rotterdam Score, with an optimal cut-off value of 4.5. Rotterdam Score demonstrated a sensitivity of 80%, specificity of 97.8%, positive predictive value (PPV) of 88.8%, and negative predictive value (NPV) of 95.7% in predicting postoperative mortality.
Conclusion: The Rotterdam Score is a highly accurate predictor of postoperative mortality in head injury patients undergoing surgery. Its CT-based assessment allows for rapid and objective prognostication, aiding clinicians in risk stratification and treatment planning. Further research with larger and more diverse populations is warranted to validate these findings and establish the generalizability of Rotterdam Score across different healthcare settings.
Paperless Classroom Paradigm: Shift toward Environmental Sustainability in the Implementation of an Emerging LMD System in Eastern DR Congo
Authors: Mubalama Leonard K. , Novoa Constanza Para , Wandarh’asima Lucien M. , Batachoka Daniel M. , Masumbuko Dieumerci R. , Murhula Irenée M. , Mushagalusa Emery M. , Kahindo Charles M.
Published: January 2025

Mass production of paper is one of the significant factors that are contributing to the increase in carbon outrush in the global ecological system. The transition to paperless systems in higher education is gaining momentum as institutions strive to reduce environmental impacts, streamline operations, and embrace digital technologies in the framework of the implementation of the LMD system in eastern DR Congo. This paper explores the implications of paperless consumption, focusing on its potential to mitigate forest destruction. The shift towards a paperless classroom offers significant environmental and financial benefits, particularly in reducing carbon emissions and conserving natural resources. The analysis revealed that a total of 16,226 students for the academic year 2021-2022 have consumed 1,125 A4-sheet annually per student giving approximately 36,508.5 reams of paper, with a total weight of 91,271.25 kilograms, thus leading to the destruction of approximately 1,521.19 trees and incurring a loss of 33,466.96 kg of CO₂ emissions that could have been absorbed. The study found that saving 1,115.54 trees would provide 24,541.88 kg of CO₂ absorption annually. This figure represents the additional CO₂ that would have been absorbed by these trees if they were left standing rather than used in paper production. Though seemingly minor per unit, the cumulative impact over the years is substantial. A total of 73% reduction in paper consumption, calculated from saving approximately 1,115.54 out of 1,521.19 trees, leads to proportional savings across related costs: $1,533,000 in paper, $664.30 in printer depreciation, $659,190 in toner, and $1,362.91 in electricity. These cumulative savings amount to a total of $2,194,217.21 annually. Overall, the shift towards a paperless environment not only contributes to significant reductions in GHG emissions but also supports cost-effective environmental stewardship, underscoring the potential benefits of adopting sustainable practices in educational settings
Perencanaan Pembelajaran Mata Pelajaran Pai dalam Kajian Teori Belajar Kognitif
Authors: Amma Tasurun , Komariyah Siti , Bahrudin Arik
Published: January 2025

This research discusses learning planning for PAI subjects in the study of cognitive learning theory, using a literature review type of research, namely the researcher collects, evaluates and synthesizes information from various sources to gain an understanding of the research topic. The research results concluded that learning planning is a systematic process that aims to develop a structured and measurable plan to achieve learning outcomes, including objectives, materials, teaching methods and evaluation. Cognitive theory, pioneered by Piaget, Bruner, and Vygotsky, emphasizes the role of mental processes, with a focus on deep understanding, development of critical thinking skills, and evaluation. In Islamic Education learning, the learning planning process uses cognitive theory studies with goal setting steps, focusing on understanding concepts, and developing critical thinking skills, then the material is designed to facilitate in-depth understanding by linking religious concepts with life contexts using selected learning methods such as discussion and problem solving , encouraging active student participation. Learning evaluation is used to measure understanding of concepts and critical thinking abilities.
Optimalisasi Pembelajaran Agama Islam Melalui Penggunaan Media Interaktif Perspektif Guru
Authors: Ula Ahmad Nilnal Munachifdlil , Hidayati Hanik
Published: January 2025

Islamic Religious Education is an integral part of education that requires innovative and effective approaches. This study aims to optimize Islamic Religious Education through the use of interactive media from the perspective of teachers. The research method used is a case study involving ten Islamic Religious Education teachers in a secondary school in Indonesia. The results show that the use of interactive media in Islamic Religious Education can increase students' interest and understanding of the subject matter. The teachers involved in this study also indicate that the use of interactive media provides variation in teaching and helps achieve learning objectives more effectively. This study makes an important contribution to the development of more interactive and effective methods of Islamic Religious Education.
Pola Komunikasi Orang Tua Dan Anak Di Era Digital: Parenting Dalam Perspektif Al-Qur’an (Kajian Surah Yusuf [12]: 4-6)
Authors: Rindiani Natasya , Razzaq Abdur , Imron Kristina
Published: January 2025

The purpose of this research is to find out parenting in QS Yusuf: 4-6 and its relevance in line with the communication patterns of parents and their children in the digital age. This research uses a type of literature by collecting data through the main source, namely the Qur'an and supporting sources in the form of articles, reading books and the web. The data analysis technique applied is to reduce the data, then present the data and finally determine the final result of the conclusion that is in line with the research. The results of his research are that parents usually wear a bad way of communication called laissez-faire, that is, parents are reluctant to chat with their children, from the consequences of freeing their children to wear gadgets that trigger the friendship between parents and their children is stuck. They should emulate Joseph's family relationship with Ya'qub who uses an interpersonal way as well as an interactive approach. Shown by the act of openness, mutual reassurance, emotional closeness in the two, Ya'qub formed it with acts of gentle interaction, civility, obedience and respect for his father and mother, tolerance and concern for his baby. The harmony for this study is that when parents wear the communication pattern recommended in QS Yusuf 4 to 6, of course family ties become harmonious. Children become more confident to express their grievances with their parents than on social media which is vulnerable to crime. Until, all hopes to achieve a happy family in the hereafter have been realized.
Analisis Dasar-Dasar Pendidikan Islam Berdasarkan Perspektif Filosofis, Akademis, Sosiologi, Politik, Dan Ekonomi
Authors: Azzahra Radita , Handayani Tutut , Zuhdiyah
Published: January 2025

Islamic education is a system that makes learners able to exert their lives in accordance with what has become the goal and not out of Islamic law and then developed based on the basic abilities of learners towards the maximum point in growth and development. The method used in writing this article is using the Library Study Method (Library Reasearch). Library study is a method of collecting data by knowing and examining the theories created by scholars who have a connection with the research topic. The basics of Islamic education are things that include fundamental principles that become the basis for carrying out education. The aspects contained in Islamic Education are Philosophical aspects which are Academic aspects which are containers or institutions that practice learning activities critical thoughts that are needed in teaching and learning activities. Furthermore, the political aspect provides evidence of the government's seriousness in controlling the education system. There is also a sociological aspect as a mutual interaction between children, teachers, and the entire community in the school environment and finally the economic aspect which is often one of the factors inhibiting children's education in Indonesia
Short-term outcomes after implementation of SABA-free asthma management with a maintenance and anti-inflammatory reliever regimen within primary care
Authors: Harrison Samantha , Goulding Emma , Read Julie , Ghosh Sudip
Published: January 2025

Aim: Short-acting β2-agonist (SABA) overuse adversely affects asthma-related outcomes and the environment. The latest Global Initiative for Asthma (GINA) report no longer recommends SABA-only therapy. Since 2020, we have implemented an inhaled corticosteroid (ICS)-containing reliever strategy for our moderately severe asthmatics within our practice population. We only administered budesonide/formoterol (BUD/FORM) via a single device maintenance and reliever therapy (MART) across this cohort and eliminated the use of SABA therapy. Methods: Our asthma registry revealed 195 patients in the cohort. All patients were invited for assessment and 101 patients agreed to this new strategy [MART + simultaneous anti-inflammatory reliever (AIR)]. The remaining 94 patients continued with MART and SABA inhalers. Both groups were followed up for 24 months. Results: There were no deaths in either group. Asthma-related hospitalizations fell by 91.5% in the SABA-free group (p = 0.003). Exacerbations requiring oral corticosteroids (OCS) fell by 82.1% in the SABA-free group over the 24-month period (p = 0.041). At the end of 24 months, 97.5% of patients in the SABA-free group remained SABA-free, with an average of 4.9 cannisters of BUD/FORM prescribed per year, compared with 7.68 cannisters in the MART/SABA groups (p = 0.00347). Conclusions: This data provides real world evidence that the use of MART/AIR with BUD/FORM simultaneously with the elimination of SABA is safe and effective for moderate asthmatics within primary care.
Gut microbiota-derived metabolites and chronic inflammatory diseases
Authors: Vargas Alejandra , Robinson Benjamin L. , Houston Kevin , Vilela Sangay Ana Rosa , Saadeh Michael , D’Souza Steve , Johnson David A.
Published: January 2025

The gut microbiota, a complex ecosystem of microorganisms, plays an essential role in maintaining immune and metabolic homeostasis. Disruption of this microbial balance, known as dysbiosis, has been increasingly implicated in the pathogenesis of chronic inflammatory conditions, including cardiovascular, gastrointestinal, and autoimmune diseases, as well as metabolic disorders such as diabetes and obesity. A crucial mechanism through which the gut microbiota exerts its effects on host physiology is via the production of bioactive metabolites. These metabolites, including short-chain fatty acids, bile acids, and tryptophan derivatives, are key in modulating immune responses and regulating metabolic functions. Dysbiosis disrupts the production and function of these metabolites, thereby contributing to immune dysregulation, chronic inflammation, and disease progression. This review examines the role of gut microbiota-derived metabolites in chronic inflammatory diseases, with a focus on their immunomodulatory and metabolic effects. A deeper understanding of these mechanisms may open the way for novel therapeutic strategies aimed at restoring immune homeostasis and mitigating the global burden of chronic inflammatory diseases.
CRYPTANALYSIS OF SIGNATURE SCHEMES BASED ON THE ROOT EXTRACTION PROBLEM OVER BRAID GROUP DOI: https://doi.org/10.37418/amsj.14.1.2
Authors: Djimnaibeye S. , Wamba G.M. , Hassan B.M. , Haggar M.S.D. , Tieudjo D. , Sow D.
Published: January 2025

Cumplido, María and al. have recently shown that the Wang-Hu digital signature is not secure and has presented a potential attack on the root extraction problem. The effectiveness of generic attacks on solving this problem for braids is still uncertain and it is unknown if it is possible to create braids that require exponential time to solve these problems. In 2023, Lin and \textit{al.} has proposed a post-quantum signature scheme similar to the Wang-Hu scheme that is proven to be able to withstand attacks from quantum computers. This paper presents evidence of an algorithm that uses mean-set attacks to obtain the private key in two different schemes, without having to solve the root extraction problem. Additionally, in the post-quantum signature version, we demonstrate that an attacker can forge a signature that will pass verification without actually recovering the private key.
Riešo kanalo tunelinis sindromas: konservatyvaus ir chirurginio gydymo veiksmingumas
Authors: Lebionka Edgar , Simanauskas Kazys
Published: January 2025

Riešo kanalo tunelinis sindromas (RKTS) yra dažniausia kompresinė neuropatija, sudaranti apie 90 proc. visų neuropatijų atvejų. RKTS gydymas skirstomas į dvi pagrindines grupes – konservatyvų (neinvazinį) ir chirurginį. Optimalaus gydymo metodo pasirinkimas, ypač ankstyvose ligos stadijose, išlieka prieštaringu. Renkantis gydymo strategiją būtina įvertinti simptomų sunkumą, trukmę, intervencijų riziką ir paciento pageidavimus. Šioje apžvalgoje glaustai pristatomi RKTS rizikos veiksniai, patofiziologija, klinika ir diagnostika.
Priklausomybė nuo tabako ir su juo susijusių gaminių: valdymo ir sprendimų paieškos
Authors: Ramanauskė Sandra , Čaplinskas Saulius
Published: January 2025

Priklausomybė nuo tabako išlieka reikšminga visuomenės sveikatos problema, kurios valdymas kelia daug iššūkių. Ji apima tiek fizinius, tiek psichologinius aspektus, todėl jos atsisakymas dažnai reikalauja kompleksinių sprendimų. Dėl stipraus priklausomybės pobūdžio staigus žalingų įpročių nutraukimas dažnai nėra sėkmingas, todėl nuoseklus ir individualizuotas požiūris galėtų prisidėti prie priklausomybės žalos mažinimo ir veiksmingesnio problemos valdymo.
Ūminiai otitai šeimos gydytojo praktikoje
Authors: Jovarė Rūta , Jonavičiūtė Bernadeta , Minelgienė Rūta , Mikulskienė Akvilė
Published: January 2025

Ūminiai otitai – tai ausų infekcijos, dažniausiai pasireiškiančios vaikams, tačiau galinčios paveikti ir suaugusiuosius. Ūminis išorinis otitas, dar vadinamas plaukiko ausimi, dažniausiai sukeliamas bakterijų, tokių kaip Pseudomonas aeruginosa ir Staphylococcus aureus. Rizikos veiksniai apima maudymąsi, ausų krapštukų naudojimą ir ausinių nešiojimą. Pagrindiniai simptomai – skausmas, niežulys ir išskyros iš ausies. Ūminis serozinis otitas atsiranda dėl skysčio susikaupimo už būgnelio ir dažniau pasireišia vaikams. Gydymas apima pagrindinės priežasties pašalinimą, o prireikus – otorinolaringologo konsultaciją. Ūminis miringitas yra būgnelio uždegimas, dažnai susijęs su virusinėmis infekcijomis. Simptomai apima staigų ausies skausmą ir klausos sutrikimus. Gydymas – skausmo malšinimas ir, jei būtina, antibiotikų vartojimas. Ūminis vidurinis otitas yra dažna vaikų infekcija, kurią sukelia tiek virusai, tiek bakterijos. Simptomai apima ausų skausmą, karščiavimą ir klausos sutrikimą. Gydymas priklauso nuo paciento amžiaus ir simptomų intensyvumo, dažniausiai pradedamas antibiotikais, jei simptomai nepraeina per 48–72 val. Svarbu vengti netinkamo antibiotikų vartojimo ir skatinti skiepytis nuo Streptococcus pneumoniae.
Peningkatan Literasi Fiqih Perdarahan Wanita Berbasis Seminar Lintas Madzhab kepada Jama'ah BKMT Kotabumi Lampung
Authors: Saadah Siti Zumrotus , Rohmah Arifiani Nailul Fauziyah
Published: January 2025

Salah satu hal yang dianggap ironis adalah rendahnya pengetahuan tentang hukum terkait perdarahan wanita bagi jama’ah BKMT Kotabumi Lampung Utara. Padahal problematika perdarahan terus mereka alami seiring banyaknya konsumsi alat kontrasepsi bagi wanita. Pengabdian ini memiliki tujuan untuk menganalisis fakta rendahnya literasi jama’ah di lapangan, melaksanaan kegiatan pengabdian berbasis seminar peningkatan literasi fiqih perdarahan wanita lintas madzhab, dan mengevaluasi hasil pengabdian. Melalui pendekatan Participatory Action Research (PAR) dengan mengadopsi desain KUPAR (Knowing, Understanding, Planning, Executing, and Reflecting), pengabdian ini menyimpulkan sebuah hasil bahwa program peningkatan literasi fiqih perdarahan ini dampak peningkatan tingkat pemahaman sesudah seminar 85%, relevansi materi dengan kebutuhan peserta 90%, kualitas penyampaian materi oleh narasumber 92%, tingkat partisipasi peserta dalam diskusi 78%. Selain itu terdapat 100% peserta yang menyarankan agar seminar dilakukan secara berkala dan lebih mendalam lagi. Rekomendasi selanjutnya dari program ini adalah dari segi peningkatan kembali durasi waktu, peningkatan jumlah nara sumber serta, pendalaman materi secara mendetail dan spesifik. Sementara terkait interaksi peserta perlu diperpanjang lagi sesi tanya jawab yang diberikan.