bluuebunny/crossref_metadata_2025 huggingface dataset:
TRAILS: Tree reconstruction of ancestry using incomplete lineage sorting
Authors: Rivas-González Iker , Schierup Mikkel H. , Wakeley John , Hobolth Asger
Published: February 2024

Genome-wide genealogies of multiple species carry detailed information about demographic and selection processes on individual branches of the phylogeny. Here, we introduce TRAILS, a hidden Markov model that accurately infers time-resolved population genetics parameters, such as ancestral effective population sizes and speciation times, for ancestral branches using a multi-species alignment of three species and an outgroup. TRAILS leverages the information contained in incomplete lineage sorting fragments by modelling genealogies along the genome as rooted three-leaved trees, each with a topology and two coalescent events happening in discretized time intervals within the phylogeny. Posterior decoding of the hidden Markov model can be used to infer the ancestral recombination graph for the alignment and details on demographic changes within a branch. Since TRAILS performs posterior decoding at the base-pair level, genome-wide scans based on the posterior probabilities can be devised to detect deviations from neutrality. Using TRAILS on a human-chimp-gorilla-orangutan alignment, we recover speciation parameters and extract information about the topology and coalescent times at high resolution.
Global epidemiology of hepatitis C virus in dialysis patients: A systematic review and meta-analysis
Authors: Kenfack-Momo Raoul , Ngounoue Marceline Djuidje , Kenmoe Sebastien , Takuissu Guy Roussel , Ebogo-Belobo Jean Thierry , Kengne-Ndé Cyprien , Mbaga Donatien Serge , Zeuko’o Menkem Elisabeth , Lontuo Fogang Robertine , Tchatchouang Serges , Ndzie Ondigui Juliette Laure , Kame-Ngasse Ginette Irma , Kenfack-Zanguim Josiane , Magoudjou-Pekam Jeannette Nina , Bowo-Ngandji Arnol , Mahamat Maimouna , Nkie Esemu Seraphine , Ndip Lucy , Njouom Richard
Published: February 2024

Dialysis is a replacement therapy for patients with End-Stage Renal Disease (ESRD). Patients on dialysis are at high risk of acquiring hepatitis C virus (HCV), which has become a leading cause of morbidity and mortality in this population. There is a wide range of prevalence of HCV in dialysis populations around the world. It is still unknown how prevalent HCV infection is among worldwide dialysis patients (including those undergoing hemodialysis and peritoneal dialysis). A review was conducted to estimate the global epidemiology of hepatitis C in dialysis patients. We searched PubMed, Excerpta Medica Database (Embase), Global Index Medicus and Web of Science until October 2022. A manual search of references from relevant articles was also conducted. Heterogeneity was evaluated by the χ2 test on Cochrane’s Q statistic, and the sources of heterogeneity were investigated using subgroup analysis. In order to assess publication bias, funnel plots and Egger tests were conducted, and pooled HCV prevalence estimates were generated using a DerSimonian and Laird meta-analysis model. The study is registered with PROSPERO under CRD42022237789. We included 634 papers involving 392160 participants. The overall HCV case fatality rate was 38.7% (95% CI = 28.9–49). The global prevalence of HCV infection in dialysis population group were 24.3% [95% CI = 22.6–25.9]. As indicated by UNSD region, country, dialysis type, and HCV diagnostic targeted; Eastern Europe had the highest prevalence of 48.6% [95% CI = 35.2–62], Indonesia had 63.6% [95% CI = 42.9–82], hemodialysis patients had 25.5% [95% CI = 23.8–27.3], and anti-HCV were detected in 24.5% [95% CI = 22.8–26.2]. Dialysis patients, particularly those on hemodialysis, have a high prevalence and case fatality rate of HCV infection. Hemodialysis units need to implement strict infection control measures.
Windblown sand hazards risk assessment along the highways based on GIS-game theory combination weight
Authors: Li Liangying , Lv Lele , Tao Zhizhong , Yin Wenhua , Li Qi , Wang Zhenqiang
Published: February 2024

Windblown sand hazards seriously threaten the safe operation of highways in desert areas. Reasonable risk assessment can provide the basis for windblown sand hazards prevention and risk reduction. To facilitate the formulation of better windblown sand hazards prevention and reduction strategies, a new windblown sand hazards risk assessment model along the highways was proposed, in which seven evaluation indicators were selected from danger of the hazard-causing factors, vulnerability of the hazard-forming environment, and the vulnerability of the hazard-bearing body. The model was established based on the combination weighting method of game theory, and the risk map was generated based on the GIS platform. Finally, the model was applied to the windblown sand hazards risk assessment along the Wuhai-Maqin Highway. The result showed that the risk of the windblown sand hazards along the Wuhai-Maqin Highway is mainly medium, low, and very low. High and very high risk windblown sand hazards sections account for only 33% of the total length of the highway. The high and very high risk highway sections of the windblown sand hazards are mainly distributed in the hinterland of shifting dunes area and near the horizontal curve with a small radius in the flat sandy land area. By comparing with the real information of windblown sand hazards along the highway, correlation was up to 85.93%, which verified the accuracy of the model. The model can be applied to windblown sand hazards risk assessment along the highways.
A lagrange programming neural network approach for nuclear norm optimization
Authors: Dai Xiangguang , Qiu Jian , Wan Chaoyang , Dai Facheng
Published: February 2024

This article proposes a continuous-time optimization approch instead of tranditional optimiztion methods to address the nuclear norm minimization (NNM) problem. Refomulating the NNM into a matrix form, we propose a Lagrangian programming neural network (LPNN) to solve the NNM. Moreover, the convergence condtions of LPNN are presented by the Lyapunov method. Convergence experiments are presented to demonstrate the convergence of LPNN. Compared with tranditional algorithms of NNM, the proposed algorithm outperforms in terms of image recovery.
A linearly decreasing deterministic annealing algorithm for the multi-vehicle dial-a-ride problem
Authors: Mortazavi Amir , Ghasri Milad , Ray Tapabrata
Published: February 2024

Dial a ride problem (DARP) is a complex version of the pick-up and delivery problem with many practical applications in the field of transportation. This study proposes an enhanced deterministic annealing algorithm for the solution of large-scale multi-vehicle DARPs. The proposed method always explores the feasible search space; therefore, a feasible solution is guaranteed at any point of termination. This method utilises advanced local search operators to accelerate the search for optimal solutions and it relies on a linearly decreasing deterministic annealing schedule to limit poor jumps during the course of search. This study puts forward a systematic series of experiments to compare the performance of solution methods from various angles. The proposed method is compared with the most efficient methods reported in the literature i.e., the Adaptive Large Neighbourhood Search (ALNS), Evolutionary Local Search (ELS), and Deterministic Annealing (DA) using standard benchmarks. The results suggest that the proposed algorithm is on average faster than the state-of-the-art algorithms in reaching competitive objective values across the range of benchmarks.
Syrian crises effect on specialty choice and the decision to work in the country among residents of six major hospitals in Syria, Damascus
Authors: Soqia Jameel , Yakoub-Agha Laila , Mohamad Lama , Alhomsi Rawan , Shamaa Mohamad Ashraf , Yazbek Albaraa , Alsaid Bayan
Published: February 2024

Assessing the impact of war on medical residents’ specialty choices and migration decisions is critical to ensure the sustainability of healthcare systems worldwide. This study aimed to evaluate the effect of the Syrian crisis on specialty choices, related factors, and decisions to work in Syria among residents of six major university hospitals in Damascus. A cross-sectional study was conducted using a validated questionnaire from 20/4/2022 to 20/5/2022, including all eligible residents with no missing data. The questionnaire was comprised of 68 items, and residents were divided into two groups: group 1 included residents who made their specialty choice after the end of the military war in Damascus 2018, while group 2 included residents who made their specialty choice (the point of submitting their lists and applying for residency) during the war. A total of 370 residents were included, with 38.4% females and 61.6% males. Our findings revealed that 30% of residents preferred working in Syria, while 43.5% preferred working abroad. The factor of a "safer and more stable life" was significantly higher in Group 1 than in Group 2 (3.86>3.5, p-value = 0.026). Additionally, Group 1 residents were more likely to choose radiology, pathology, laboratory, and psychiatry specialization as their specialties, while choosing surgical specializations and hematology decreased compared to Group 2 (p-value<0.05). Factors related to social life were rated higher by group 1 (mean = 3.31) than by group 2 (mean = 2.27, Standard deviation = 0.19, p-value = 0.002). Moreover, the factor of "a specialization to facilitate traveling abroad" was significantly higher in Group 1 (2.69>2.21, Standard deviation = 0.22, p-value = 0.033). The Syrian crisis and its economic aftermath have influenced residents’ specialty choices and practice locations. Even after the war’s end, the high level of migration intentions could negatively affect the quality of provided healthcare services.
Current approaches addressing oral health practitioners’ responsiveness to child abuse and neglect: A scoping review protocol
Authors: Han Heuiwon , Koziol-McLain Jane , Morse Zac , Lees Amanda B.
Published: February 2024

Introduction

Child abuse and neglect (CAN) poses significant risks, causing severe and long-lasting effects on a child’s well-being, including physical and mental health and learning and socializing capabilities. Oral health practitioners (OHPs) uniquely position themselves to identify signs of maltreatment in the orofacial area, offer appropriate support, and collaborate with a multidisciplinary team. The literature has shown that OHPs under-report child protection concerns to a statutory child protection agency. Responding to CAN is often hindered by various factors, such as the fear of making false accusations and insufficient knowledge to detect and report potential cases. However, the literature lacks a comprehensive understanding of the strategies and interventions that can address the responsiveness of OHPs and other professionals to child protection issues. This scoping review aims to provide a broad overview and map the literature on the existing approaches to enhance the responsiveness of OHPs in child protection.

Materials and methods

The proposed scoping review will be conducted following the JBI methodology for scoping reviews guideline and reported using the PRISMA-ScR guideline. The first exploratory search is conducted to refine the search strategy and inclusion and exclusion criteria. The second search will include MEDLINE (EBSCO), CINAHL (EBSCO), Dentistry & Oral Science Source (EBSCO), Cochrane Library, and Scopus, with a date range from January 2000 to March 2023. The third search will involve reference list searching and gray literature searching in Google and Google Scholar. Government and international health organizations’ websites will be searched for policies and guidelines. The review will consider studies that report the current approaches to address OHPs’ responsiveness to CAN in any setting. Two reviewers will independently select sources and extract data. Any disagreements will be resolved by consensus of the research team. The extracted data will be presented in a tabulated chart with a narrative summary.
Non-contrast free-breathing 2D CINE compressed SENSE T1-TFE cardiovascular MRI at 3T in sedated young children for assessment of congenital heart disease
Authors: Ristow Inka , Hancken-Pauschinger Caroline-Viktoria , Zhang Shuo , Stark Maria , Kaul Michael G. , Rickers Carsten , Herrmann Jochen , Adam Gerhard , Bannas Peter , Well Lennart , Weinrich Julius Matthias
Published: February 2024

Cardiac MRI is a crucial tool for assessing congenital heart disease (CHD). However, its application remains challenging in young children when performed at 3T. The aim of this retrospective single center study was to compare a non-contrast free-breathing 2D CINE T1-weighted TFE-sequence with compressed sensing (FB 2D CINE CS T1-TFE) with 3D imaging for diagnostic accuracy of CHD, image quality, and vessel diameter measurements in sedated young children. FB 2D CINE CS T1-TFE was compared with a 3D non-contrast whole-heart sequence (3D WH) and 3D contrast-enhanced MR angiography (3D CE-MRA) at 3T in 37 CHD patients (20♂, 1.5±1.4 years). Two radiologists independently assessed image quality, type of CHD, and diagnostic confidence. Diameters and measures of contrast and sharpness of the aorta and pulmonary vessels were determined. A non-parametric multi-factorial approach was used to estimate diagnostic accuracy for the diagnosis of CHD. Linear mixed models were calculated to compare contrast and vessel sharpness. Krippendorff’s alpha was determined to quantify vessel diameter agreement. FB 2D CINE CS T1-TFE was rated superior regarding image quality, diagnostic confidence, and diagnostic sensitivity for both intra- and extracardiac pathologies compared to 3D WH and 3D CE-MRA (all p<0.05). FB 2D CINE CS T1-TFE showed superior contrast and vessel sharpness (p<0.001) resulting in the highest proportion of measurable vessels (740/740; 100%), compared to 3D WH (530/620; 85.5%) and 3D CE-MRA (540/560; 96.4%). Regarding vessel diameter measurements, FB 2D CINE CS T1-TFE revealed the closest inter-reader agreement (Krippendorff’s alpha: 0.94–0.96; 3D WH: 0.78–0.94; 3D CE-MRA: 0.76–0.93). FB 2D CINE CS T1-TFE demonstrates robustness at 3T and delivers high-quality diagnostic results to assess CHD in sedated young children. Its ability to function without contrast injection and respiratory compensation enhances ease of use and could encourage widespread adoption in clinical practice.
Impact of two endotracheal tube fixation on the incidence of peri-oral lesions: Elastic adhesive strips versus cord in a protective sheath. Study protocol for a cluster cross-over randomized trial
Authors: Zinzoni Vanessa , Planche Lucie , Le Potier Sophie , Robin Laurence , Le Parco Cécile , Terrat Philippe , Leroyer Marie-Hélène , Atger Romain , Dauvergne Jérôme E. , Muller Lucie , Fontaine Laetitia , Morand Célina , Dennemont Pascaline , Paillard Ophélie , Vastral Servane , Dardaine Baptiste , Le Guillou Sylvie , Maquigneau Natacha , Martin Stéphanie , Lachérade Jean-Claude
Published: February 2024

Background

Endotracheal tube fixation in ventilated patients must be appropriate to ensure security during mechanical ventilation and prevent skin lesions. The incidence of endotracheal tube‐caused pressure ulcers ranges from 7% to 45%. Various endotracheal tube fixations are used in intensive care units (ICUs) worldwide. By pressure exercised on the skin, these systems could lead to mucosal and skin peri-oral lesions. The main objective of this study is to evaluate the impact of the two fixation systems most commonly used in French ICUs (adhesive elastic band versus fixation cord with PolyVinyl Chloride (PVC) sheath) on the incidence of these peri-oral skin lesions.

Methods

This studyis a multicenter, open-label, controlled, superiority, cluster cross-over randomized trial. 768 patients will be recruited in the 16 ICUs involved. The inclusion of patients will be carried out over two 12-month periods. Each site begins with one of the evaluated fixation systems: elastic adhesive tape or cord associated with a protective sheath. After a 4-month break, each site switches to the other fixation system. The primary outcome is the development of at least one peri-oral lesion during the first ten days of maintaining an orally inserted endotracheal tube. The presence of lesions is assessed by a blinded adjudication committee using photographs taken daily.

Discussion

This study is the first multicenter, randomized trial designed to evaluate the impact of elastic adhesive tape versus fixation cord with PVC sheath on the incidence of peri-oral lesions. The results will provide data which could change and standardize care practices.

Trial registration

https://www.clinicaltrials.gov. Reference number: NCT04819425.
Identification of self-incompatibility alleles in Quince (Cydonia oblonga Mill.)
Authors: Sadeghnejad Sara , Abdollahi Hamid , Davoodi Daryoush , Tatari Maryam , Khosroshahli Mahmoud
Published: February 2024

The Quince (Cydonia oblonga Mill.), typically known for its self-compatibility, surprisingly presents a degree of self-incompatibility. This research focused on exploring the diversity within the self-incompatibility gene locus (S) in various C. oblonga genotypes. Through meticulous DNA sequencing, the study sought to unearth potential novel S alleles. In the process of genotyping the S gene across multiple quince genotypes, not only were the previously documented S1 and S2 alleles identified, but this investigation also uncovered two previously unrecognized alleles, termed S4 and S5. These alleles, particularly S4, emerged as the most prevalent among the tested genotypes. To corroborate the findings derived from DNA sequencing, the study employed pollen tube growth germination assays. These assays elucidated a higher pollen germination rate in the Ardabil2 genotype in contrast to Behta. Additionally, the study involved assessing pollen tube growth in both Ardabil2 and Behta through cross-pollination techniques, meticulously tracking the development of pollen tubes at various stages. Remarkably, the outcomes demonstrated that the Behta genotype possesses self-incompatibility, whereas the Ardabil2 genotype showcases a notable degree of self-compatibility. This groundbreaking discovery of new S alleles in quince not only affirms the species’ self-compatibility but also sheds light on the complexities of allelic diversity and its impact on self-incompatibility. Such insights are invaluable for enhancing the yield of quince orchards through strategic breeding programs.
A América do Sul no governo Bolsonaro (2019-2022)
Authors: Correa Paulo Gustavo Pellegrino , Silva Ivan Henrique de Mattos e
Published: February 2024

O presente artigo tem como objetivo principal a discussão sobre as mudanças de diretrizes da Política Externa Brasileira (PEB) durante o governo de Jair Bolsonaro (2019-2022) para a América do Sul. O subcontinente foi durante duas décadas plataforma de ação internacional da PEB após o fim da Guerra Fria e a redemocratização do Brasil. Estratégias distintas tiveram o entorno geográfico como base diplomática fundamental e ações bi e multilaterais fortaleceram a América do Sul como entidade geopolítica com forte protagonismo brasileiro. Entretanto, o governo Bolsonaro se elegeu a partir de um discurso que buscava mudanças substantivas na tradicional diplomacia nacional, deslocando as relações existentes no subcontinente. Nossa discussão será focada na política externa de Bolsonaro para América do Sul e de como os preceitos que alicerçam o bolsonarismo refletiram no deslocamento diplomático para a região. Faremos uma breve recapitulação da PEB para a América do Sul desde os anos 1990. Em seguida, apresentaremos os conceitos e base ideológicas do bolsonarismo, assim como sua conexão internacional. Finalmente, discutiremos as ações diplomáticas do período bolsonarista para o entorno geográfico e suas consequências para os existentes projetos regionais existentes.
Biblio Informa
Authors: Figueiredo Elida Moura , Dantas Cleide Furtado Nascimento , Lima Adriana Araújo de , Pires Erik André de Nazaré
Published: February 2024

O texto aborda o processo de criação e disseminação de um produto informativo para a comunidade acadêmica atendida pela Biblioteca Benedicto Monteiro (BBM) do Campus Universitário de Ananindeua da Universidade Federal do Pará (UFPA), localizado na Região Metropolitana de Belém, o Biblio Informa. Tal produto foi pensado como estratégia no sentido de influenciar positivamente no combate a desinformação dos usuários da biblioteca, se antecipando a possíveis informações e notícias falsas que por ventura cheguem a comunidade acadêmica local, assim como para divulgar serviços, eventos e as novidades no acervo da biblioteca.
Bibliotecários como mediador da informação entre acervos de bibliotecas e bibliografias de projetos de cursos
Authors: Almeida Aline Christian Pimentel , Santos Simone de Fátima Rodrigues dos
Published: February 2024

Trabalho em formato de Resumo Expandido.
Contribuições para o combate à desinformação durante a pandemia da covid-19
Authors: Sanches Priscila Elizabeth Ferreira Duarte , Oliveira Maria Lívia Pachêco de
Published: February 2024

Trabalho em formato de Resumo Expandido.
Auto-Brewery Syndrome After COVID-19 Infection
Authors: Yates Sarah R. , Saito Akira
Published: February 2024

Auto-brewery syndrome (ABS) is a rare medical condition, wherein gut microbiota ferment carbohydrates to alcohol. Risk factors for ABS include diets high in carbohydrates and sugars, diabetes mellitus, prior gastrointestinal surgery, nonalcoholic fatty liver disease, and certain genetic mutations, among others. We provide a case of ABS that developed after known COVID-19 infection, which may be one of the contributing factors to its development.
Nintedanib-Induced Colitis Can Mimic Inflammatory Bowel Disease
Authors: Odah Tarek , Karime Christian , Hashash Jana G. , Farraye Francis A.
Published: February 2024

Nintedanib is a medication that has been increasingly used for treatment of idiopathic and progressive pulmonary fibrosis. In this case series, we describe 3 patients with colitis symptoms associated with nintedanib use. Nintedanib discontinuation resulted in symptomatic resolution in all patients. Budesonide decreased symptoms in 1 patient. Clinicians should be vigilant in taking a thorough medication history and include nintedanib as a cause for gastrointestinal symptoms including colitis.
A modalidade argumentativa polêmica nas redes sociais
Authors: Pires Zem El-Dine Igor
Published: February 2024

O artigo busca explorar a modalidade argumentativa polêmica por meio de interações em redes sociais. O objetivo é relacionar a desqualificação do outro, à cultura do ‘cancelamento’ e o discurso de ódio nas redes sociais, considerando aspectos constitutivos da polêmica: a dicotomização de teses; a polarização social e a desqualificação do outro. O arcabouço teórico-metodológico utilizado é constituído por Ruth Amossy (2017, 2018), em diálogo com os estudos de Judith Butler (2021), acerca do discurso de ódio. Como resultado, foi possível perceber que as redes sociais são espaços de interação digital que iteram formas de preconceito, de discriminação e de ofensas contra grupos minoritários e vulneráveis socialmente. A linguagem é o canal de comunicação utilizado nas plataformas digitais que pode machucar as pessoas por meio dos atos de fala. Nesse sentido, as discussões apresentadas neste artigo mobilizam debates necessários sobre o discurso de ódio e a cultura do ‘cancelamento’.
Vozes midiáticas sobre o sujeito indígena em Dourados-MS e o falar de si
Authors: Zanzi Jaqueline , De Melo Silvia Mara
Published: February 2024

Temos como objetivo, neste artigo, apresentar reflexões acerca das representações pela mídia local no que concerne aos sujeitos indígenas sobreviventes no estado do Mato Grosso do Sul, mais especificamente na Reserva Indígena de Dourados. Além de enunciados midiáticos, nossa pesquisa contou ainda com relatos desses sujeitos, a fim de detectar nas regras de formação discursiva eventuais dispositivos de poder, que muitas vezes incidem, tanto no modo como ocorre o processo de subjetivação dessas pessoas, quanto na forma como isso aparece na mídia. Metodologicamente, valemo-nos de recortes feitos em notícias e reportagens veiculadas em jornais on line de Dourados, entrevistas e pesquisa bibliográfica. Empregamos como referencial teórico os Estudos Discursivos Foucaultianos, comentadores de Michel Foucault, Goffman para a abordagem sobre estigmas, entre outros. Concluímos com esta análise que a mídia não representa a realidade e acaba por reforçar os estigmas e estereótipos já tão engessados na sociedade douradense quando se trata de sujeitos indígenas. Por isso, ouvi-los para a constituição dessa análise permitiu-nos conhecê-los e perceber como se subjetivam pelo olhar midiático e cultural.
Palavras-chave: Sujeitos Indígenas; Estudos Discursivos Foucaultianos; Estigmas.
Legalidade como efeito de sentido
Authors: Marques Juliene
Published: February 2024

A partir do Projeto de Extensão “Mulheres Sim - Empoderar é libertar mulheres: educação integral, arte e trabalho”, realizado pelo Instituto Federal de Santa Catarina, em 2018, no Presídio Feminino de Tubarão – SC, este artigo apresenta como corpus um recorte de entrevista narrativa realizada com uma mulher em situação de privação de liberdade participante do projeto. Como objetivo geral, estabelece-se a ação de analisar as condições de produção do cárcere e seus efeitos de sentido no sujeito encarcerado e, para tanto, traça-se um trajeto teórico-analítico de investigação, contando com a Análise de Discurso pêcheuxtiana como aporte teórico, bem como com alguns pressupostos da filosofia política contemporânea. Diante de um embate entre o corpus e documentos legais referentes ao funcionamento do cárcere, a investigação destacou a legalidade como um efeito de sentido que faz a manutenção de direitos: para alguns, os assegura; para outros – inseridos em um sistema prisional entendido como legal –, apresenta-se como falta.
Las transición(es) de la maternidad española (1975-1999)
Authors: Romano Alejandra Suyai
Published: February 2024

El presente trabajo pretende analizar el fenómeno de la maternidad en la Transición española en dos movimientos sociales de mujeres de la época que registran, a los efectos de la investigación historiográfica feminista, diversos modos de apropiación, negociación y resignificación de la práctica social materna. Así, sigo los aportes de Adrienne Rich (1998) en la diferenciación entre institución y experiencia de la maternidad para indagar, por una parte, en la configuración de los movimientos feministas sindicales y de izquierda en la década de los ‘70, y por otra, en la recuperación del agenciamiento político poco abordado de las “maternidades robadas” desde finales de la etapa franquista hasta bien entrados los años democráticos de los ‘90. Como hipótesis principal postulo que si bien ambas reformulan las operaciones de sentido respecto de las narrativas maternas del franquismo, toman posiciones diferenciadas en cuanto a las formas de politización que la naturaleza dual de la maternidad presenta. Mientras que para las primeras, sostengo que la relación materna se establece como una institución a rechazar, en tanto no conforma una reivindicación prioritaria, para las segundas es precisamente el agenciamiento de su experiencia materna lo que permite politizar la búsqueda filial de sus hijos robados así como la restitución de sus identidades biológicas. A pesar de sus diferencias y de la invisibilización de éstas últimas en la historiografía reciente, ambas producen una fisura en el discurso hegemónico patriarcal al arrojar luz sobre la existencia de otras lógicas políticas que cuestionan modos de vivir, crean estrategias de resistencia y disputan experiencias colectivas en el terreno de la arena pública (pero también personal) política.
Subjetividades encontradas
Authors: Alonso Luciano
Published: February 2024

En el presente texto se argumenta que las resistencias, negaciones o impugnaciones a las memorias que condenan en Argentina el terror de Estado de 1975-1983, pueden referenciarse por un lado a los componentes autoritarios de la sociedad, exacerbados en un proceso de polarización política, y por el otro a una más amplia subjetividad neoliberal.

Tras un largo proceso de luchas iniciado en la etapa de la transición a la democracia, las memorias propuestas por el movimiento por los derechos humanos llegaron a ser hegemónicas en Argentina. Pero en la última década ese predominio fue puesto en cuestión. Recurriendo a diversas fuentes de información, se destaca la emergencia cada vez más frecuente de memorias antidemocráticas y a favor de la represión. El texto concluye con consideraciones acerca de la interpretación que puede darse a ese proceso en atención a variables complejas, incluyendo la producción social de las subjetividades.
América Latina y el Caribe en las políticas y procesos de internacionalización de la UNL: a propósito del 10º Aniversario de la Cátedra Abierta de Estudios Latinoamericanos “José Martí”
Authors: Canteros Guillermo Agustín
Published: February 2024

Reseña del libro Nuestra América en las políticas y procesos de internacionalización de la UNL. Reflexiones y aperturas en el 10º Aniversario de la Cátedra Abierta de Estudios Latinoamericanos “José Martí”. Copes, Ana y Canteros, Guillermo (Directores del Volumen). Universidad Nacional del Litoral. Santa Fe, 2022, 319 páginas.
Investigación pedagógica para solución de conflictos desde la educación de la primera infancia como aporte a la paz territorial
Authors: Pedraza Avila Nancy Milena , Mosquera Téllez Jemay
Published: February 2024

Este estudio tuvo como propósito establecer la forma en que la inteligencia emocional y los valores pueden ser aprovechados en la solución de conflictos y la construcción de escenarios de paz de niños y docentes del área rural, para lo cual se abordó el caso del municipio colombiano de Chitagá (Norte de Santander), en el que se presenta escaza atención institucional infantil y baja solución de conflictos en el ámbito escolar. Para ello se utilizó enfoque cualitativo basado en un diseño etnográfico, con un muestreo aleatorio de participantes para la aplicación de instrumentos. El procesamiento y análisis de la información se realizó con ayuda de una matriz de antecedentes y otra matriz de categorización axial. Como resultado se obtuvo el diseño de una propuesta pedagógica dirigida a la educación de la primera infancia en actitudes y valores para la construcción de paz en entidades educativas y de salud.
Reconfiguraciones identitarias en madres proveedoras cuando los padres son los principales cuidadores de sus hijas e hijos
Authors: González Viveros María Constanza , Jaramillo Sierra Ana Lucía , Vargas Trujillo Elvia
Published: February 2024

Se presentan los resultados de los procesos de reconfiguración identitaria de las mujeres de siete parejas heterosexuales en las cuales ellas son las principales proveedoras económicas del hogar y ellos son los principales cuidadores de sus hijos. Los resultados de esta investigación cualitativa mostraron que esta distribución de roles alternativa les permite generar unas narrativas de sí mismas más equitativas, que les generan mayor bienestar. Esto, en tanto les posibilita continuar su desarrollo profesional en el contexto de sus proyectos vitales, experimentar la maternidad desde el gozo y no desde la culpa, y valorar el rol de sus parejas como principales cuidadores. No obstante, estas identidades se ven coartadas cuando las mujeres interiorizan algunas normas de género presentes en la cultura. Se discuten las implicaciones de los resultados en el desarrollo de iniciativas de promoción de la equidad de género.
Medicina tradicional tikuna en tiempos de postpandemia. Una perspectiva desde la comunicación para el cambio social
Authors: Ortiz Nova Yaneth , Manrique Villanueva Lina
Published: February 2024

Con el objetivo de comprender las diversas formas de mantener y transmitir los conocimientos tradicionales sobre el manejo de los recursos naturales silvestres y domesticados para prevenir y tratar la enfermedad de los miembros de la comunidad tikuna del Resguardo de San Sebastián de los Lagos, en Leticia (Amazonas), esta investigación utiliza elementos del método etnográfico y la Investigación- Acción- Participativa (IAP). Este proyecto se desarrolló en tres fases: diagnóstica, acción participativa y sistematización de la información. En el contexto del trabajo de campo con la comunidad se realizaron visitas en julio de 2022 al huerto, la chagra y el bosque con las mujeres de la comunidad, recolectando hojas de un herbario que funcionó como pretexto para el diálogo sobre las propiedades medicinales de las plantas. Los resultados muestran que las personas que lograron mantenerse dentro de la comunidad, realizando cuidado a partir de la medicina tradicional con hojas, sahumerios y cuidado, lograron recuperarse del Covid-19.
Editorial
Authors: González Pablo Guadarrama
Published: February 2024

Cultura Latinoamericana se ha caracterizado por promover los estu-dios de investigadores de distintas partes del orbe, interesados en pro-fundizar y divulgar el conocimiento de los aportes de diversos actores de esta región a la cultura universal. En este número se pretende continuar dicha labor y, con ese ob-jetivo, en su sección Historia y Política se presenta el artículo “De la comuna a la parcela. Crítica de la película Los reyes del mundo”, en el que Mateo Romo plantea con acierto que la idea motriz de la película, en cuanto filme que presenta una genuina lectura sobre la violencia y propicia un viaje a las profundidades de los que sufren, es, a su vez, una experiencia de concientización colectiva
Pablo Guadarrama González, entre anacronismo y ucronismo
Authors: Tovar González Leonardo
Published: February 2024

¡Es Pablo Guadarrama González un filósofo pasado de moda? Mejor dicho, ¿el modo de hacer filosofía de Pablo Guadarrama González está pasado de moda? Y, dado que Pablo Guadarrama González hace filosofía latinoamericana, ¿la filosofía latinoamericana está pasada de moda? Estos son interrogantes políticamente incorrectos y filosófica-mente impertinentes que me asaltan después de leer Pablo Guadarrama González, filósofo latinoamericano, el pormenorizado libro en el que el filósofo colombiano radicado en el Caribe, Carlos Rojas Osorio (2022), reconstruye la obra latinoamericanista del cubano residente en Colombia.
Las representaciones literarias y sociales en la obra "Los mexicanos pintados por sí mismos"
Authors: Galicia Isasmendi Erika
Published: February 2024

En esta propuesta se analizan las representaciones simbólicas que se le otorgaron a la mujer mexicana decimonónica recreadas por la literatura costumbrista. Tal revisión se hará a partir del estudio de la historia social, el cual nos ayudará a comprender mejor a las mujeres como sujetos sociales en su convivencia cotidiana en el ámbito social y en el laboral. La obra fue editada en el año de 1854 y está ilustrada con litografías que retratan la actividad laboral femenina, así como las costumbres y las interpretaciones sociales que llegaron a crear ideales del modelo femenino mexicano. Las mujeres objeto de nuestro estudio serán examinadas en variadas actitudes, actividades y quehaceres do-mésticos, lo que nos permitirá conocer una tipología de personajes como la recamarera, la casera, la costurera, la estanquillera, la chiera, la partera, la china y la coqueta.
El Kaziyadu de Orlando: por un Estado regional hacia el neofederalismo
Authors: Sánchez Ángel Ricardo
Published: February 2024

Las ideas sobre la regionalización territorial y organización del Estado colombiano, elaboradas durante una extensa e intensa investigación del connotado científico social Orlando Fals Borda, presentan un gran sentido de actualidad y enriquecen el debate sobre los planes de desarrollo y las políticas públicas. La pertinencia de las propuestas de federalismo, neofederalismo o Estado regional cobran relevancia, ante la gravedad de las crisis del Estado nacional, soportada en el fraccionamiento territorial, sumado a la incidencia de los procesos económicos, políticos, culturales y, de manera relevante, los ambientales. Es el propósito de este artículo demostrar la relevancia de los mencionados estudios y destacar su gran calidad analítica, al tiempo que reconocerlos como guía me-todológica para la investigación-acción-participativa
Filme für die Zukunft
Authors: Boelens Marlo , Förstner Dirk , Hänger Christian
Published: February 2024

Technische Entwicklungen haben das Bundesarchiv veranlasst, die Sicherung von Filmen durch Umkopieren auf neue Filmrollen zu beenden. Zukünftig erfolgt die langfristige Sicherung ausschließlich in digitaler Form, auch wenn die Filmrollen weiterhin unter klimatisierten Bedingungen aufbewahrt werden. Am Standort Hoppegarten werden alle Arbeitsschritte der digitalen Postproduktion vom Audio- und Filmscannen über die Lichtbestimmung bis zum Mastering angeboten.
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc
Authors: Wang Yong , Hu Jianping , Chen Chen , Li Yongbo
Published: February 2024

This study aimed to clarify the role of pituitary tumor-transforming gene 1 (PTTG1) in proliferation, migration, invasion, and aerobic glycolysis of pancreatic cancer cells, and evaluate the potential of PTTG1 as a therapeutic target. PTTG1 expression in pancreatic cancers was analyzed using the GEPIA databank. In the Panc1 cell with the PTTG1 knockdown or Mia-PaCa2 cells with PTTG1 overexpression, the cell proliferation was evaluated using cell viability curves and colony formation, and wound heal assay and transwell assay were performed to evaluate the migration and invasion, respectively. Furthermore, a western blot was performed to evaluate the expressions of PTTG1, proliferating cell nuclear antigen, E-cadherin, N-cadherin, and c-myc. Meanwhile, the glucose uptake, extracellular acidification rates (ECAR), and oxygen consumption rates (OCR) were analyzed. Our results showed that PTTG1 expression is upregulated in pancreatic cancer, which promoted cell proliferation. Low PTTG1 contributed to higher disease-free survival and overall survival. In Panc1 cell, PTTG1 knockdown resulted in reduced cell viability and colony formation. The migration and invasion abilities of the cells were also reduced in Panc1 with PTTG1 knockdown. Correspondingly, PTTG1 knockdown decreased c-myc expression, glucose uptake, ECAR, and OCR in Panc1 cells. In Mia-PaCa2 cells, PTTG1 overexpression promoted cell proliferation, aerobic glycolysis, and translocation of β-catenin to the nucleus by regulating c-myc. In conclusion, PTTG1 induces proliferation, migration, and invasion, and promotes aerobic glycolysis in pancreatic cancer cells via regulating c-myc, demonstrating the potential of PTTG1 as a therapeutic target.
Role of serum B-cell-activating factor and interleukin-17 as biomarkers in the classification of interstitial pneumonia with autoimmune features
Authors: Zhao Lihong , Liu Li , Liu Yehua , Zheng Hong , Jiang Ping
Published: February 2024

Interstitial pneumonia with autoimmune features (IPAF) is a type of interstitial lung disease (ILD) with immune features that do not meet the diagnostic criteria for specific connective tissue diseases (CTDs). This retrospective case–control study investigated the role of serum B-cell-activating factor of the tumor necrosis factor family (BAFF) and interleukin (IL)-17 as biomarkers for IPAF. The differences in serum BAFF, IL-17, and IL-10 were compared among patients with idiopathic pulmonary fibrosis (IPF), IPAF, ILD associated with CTD (CTD-ILD), and healthy controls. The patients were treatment naïve. The correlations of BAFF with IL-10, IL-17, and pulmonary function were analyzed. The classifiable value of BAFF for IPAF was examined. The results showed that the serum levels of BAFF and IL-17 in the IPAF and CTD-ILD groups were higher than in the IPF group. High BAFF levels and high predicted diffusion capacity of the lungs for carbon monoxide (DLCO) were independent predictive factors for IPAF vs IPF. In the IPAF and CTD-ILD groups, serum BAFF levels were negatively correlated with predicted values of forced vital capacity (FVC%) and diffusing capacity of the lungs for carbon monoxide (DLCO%) and positively correlated with serum IL-17 and IL-10 levels. The cutoff value of combined BAFF and IL-17 was 0.704, and the sensitivity and specificity for classifying IPAF were 78.9 and 95.7%, respectively. In conclusion, combining serum BAFF and IL-17 as a biomarker may have classifiable value in differentiating IPAF from other forms of ILD.
A case of Trousseau syndrome: Screening, detection and complication
Authors: Liu Hui , Jiang Meng , Wu Nan , Liu Qingxin , Fan Xueli
Published: February 2024

Trousseau syndrome (TS) is a malignant tumor-mediated complication of the hypercoagulable state with an unknown etiology. Laboratory testing results in patients with TS have indicated elevated D-dimer levels. The imaging analysis in patients who had undergone stroke has shown the presence of several cerebral infarction lesions in multiple regions. Since patients have had malignant tumors for a long time when they suffer from a secondary stroke, the optimum time for radical tumor treatment is usually missed. This study reports a case to improve the early screening and detection of TS and reduce the risk of recurrence of cerebral infarction.
Preparation of Cu2+/TA/HAP composite coating with anti-bacterial and osteogenic potential on 3D-printed porous Ti alloy scaffolds for orthopedic applications
Authors: Haitao Xu , Siyuan Li , Sutong Guo , Yu Guo , Peirong Xu , Ling Wang , Yujian Ding , Dehong Feng
Published: February 2024

Because of stress shielding effects, traditional titanium (Ti) alloy scaffolds have a high elastic modulus, which might promote looseness and bone disintegration surrounding the implant, increasing the likelihood of a second surgery. In contrast, 3D-printed porous Ti alloy scaffolds can reduce the scaffold weight while enhancing biocompatibility. Further, these scaffolds’ porous nature allows bone tissue ingrowth as well as strong pore connectivity, which can improve nutrient absorption. Nevertheless, bare Ti alloy implants may fail because of inadequate bone integration; hence, adding a coating on the implant surface is an effective technique for improving implant stability. In this study, a composite coating comprising hydroxyapatite (HAP), chitosan (CS), tannic acid (TA) and copper ions (Cu2+) (Cu2+/TA/HAP composite coating) was prepared on the surface of 3D printed porous Ti alloy scaffolds using electrophoretic deposition. Using the standard plate count method, Live/Dead bacteria staining assay, FITC Phalloidin and 4′,6-diamidino-2-phenylindole staining assay, and live/dead staining of cells we determined that the composite coating has better antibacterial properties and cytocompatibility as well as lower cytotoxicity. The Alkaline Phosphatase assay revealed that the coating results showed good osteogenesis potential. Overall, the composite coatings produced in this investigation give new potential for the application of Ti alloys in clinics.
On the correspondence between periodic solutions of differential and dynamic equations on periodic time scales
Authors: Tsan Viktoriia , Stanzhytskyi Oleksandr , Martynyuk Olha
Published: February 2024

This paper studies the relationship between the existence of periodic solutions of systems of dynamic equations on time scales and their corresponding systems of differential equations.
We have established that, for a sufficiently small graininess function, if a dynamic equation on a time scale has an asymptotically stable periodic solution, then the corresponding differential equation will also have a periodic solution.
A converse result has also been obtained, where the existence of a periodic solution of a differential equation implies the existence of a corresponding solution on time scales, provided that the graininess function is sufficiently small.
Fully automated chemiluminescence microarray immunoassay for detection of antinuclear antibodies in systemic autoimmune rheumatic diseases
Authors: Yuan Dandan , Yang Xue , Ji Chen , Sun Guo , Xu Yang , Cao Ye , Ye Yan , Wang Tingting , Hu Zhigang
Published: February 2024

Objectives

Detection of specific antinuclear antibodies is very important in term of diagnosis, prognosis and management of patients with systemic autoimmune rheumatic diseases. Chemiluminescence microarray immunoassay (CLMIA) is a microdot array-based method that allows simultaneous detection of multiple antinuclear antibodies, which received increasing attention.

Methods

A CLMIA method that can detect 14 kinds of antinuclear antibodies was established and optimized. Basic performance and diagnostic performance of CLMIA was evaluated by comparing it with line immunoassay (LIA) and indirect immunofluorescence (IIF).

Results

Through conditional exploration, the optimal blocking time and blocking temperature were determined to be 18 h and 25 °C, respectively. The enzyme-labeled secondary antibody reaction concentration was 0.1 μg/mL, the incubation temperature of serum and enzyme-labeled secondary antibody were 30 °C, and the incubation time of serum and enzyme-labeled secondary antibody were 40 min. After parameter optimization, CLMIA demonstrated high accuracy with a relative bias <15 %; high sensitivity with detection limits below 3 IU/mL for dsDNA and below 1 RU/mL for other ANAs; and high reproducibility with both intra-assay and inter-assay coefficients of variation (CV) <15 %.The CLMIA detection method established in this study was also demonstrated to have good clinical diagnostic performance, showing the highest area under curve (AUC=0.87, p=0.042 and p=0.03). The CLMIA and LIA revealed substantial to good agreements on specific antinuclear antibodies except anti-dsDNA, with the Cohen’s kappa from 0.72 to 0.89. Samples that produced discrepant results between the CLMIA and LIA methods were further analyzed. Upon additional testing, most of these samples were ultimately determined to have been correctly detected by the CLMIA assay rather than the LIA assay, suggesting that CLMIA also shows some superiority in diagnosing dsDNA.

Conclusions

The CLMIA could become a potential routine method for detecting ANAs with the advantages of good detection performance.
Multifunctional hydrogels for wound healing
Authors: Yang Xinyu , Li Jinyan , Chen Xi , Wang Tao , Li Guifei , Zhang Kunxi , Yin Jingbo , Cui Haiyan
Published: February 2024

The process of wound healing is complex and dynamic. Given the unique nature of the skin, wound healing requires dressings that meet a wide range of functional requirements. Due to their unique structure and properties, hydrogel dressings provide ideal conditions for supporting the process of wound healing and can be enhanced with additional functions to meet the specific requirements of different types of wounds. Compared to traditional wound dressings, the newly developed hydrogel wound dressing offers several advantages, including its soft texture, ability to retain moisture, oxygen permeability, and comfort. With the advancement of medical technology, higher demands are being placed on the functionality of hydrogel dressings. Therefore, this paper offers a comprehensive overview of hydrogel wound dressings with various functions. These functions primarily include hemostatic hydrogel dressings, antibacterial hydrogel dressings, angiogenesis-promoting hydrogel dressings, and other functional hydrogel dressings. The paper also reviews the research and application of these dressings in recent years.