bluuebunny/crossref_metadata_2025 huggingface dataset:
Proposal for the conversion of Eucalyptus urograndis into bioethanol via acid hydrolysis, using the concepts of biorefineries
Authors: Camargo Sâmique Kyene de Carvalho Araújo , Ventorim Gustavo , Camargo Bruno Silva , Salvador Rodrigo , de Carvalho Araújo Cristiane Karyn , de Carvalho Araújo Camilla Kawane Ceciliano , Henrique Antunes Vieira Fábio
Published: September 2022

The production of bioethanol from materials of renewable origin is an important matter for a more sustainable economic development, and at the same time it challenges researchers to seek more efficient technologies that can make it viable. Wood is a profitable and advantageous option, with special emphasis on eucalyptus, whose cultivation has high turnover in Brazil, where land is available for this purpose. Therefore, the goal of this research was to optimize the hydrolysis stage using acid instead of enzymes for the conversion of chips of Eucalyptus urograndis into bioethanol, with additional co-production of furfural and commercial lignin, in order to make the process more advantageous. To obtain bioethanol, a pre-treatment adapted from autohydrolysis was performed to remove the hemicelluloses, followed by soda pulping to remove the lignin and, finally, the acid hydrolysis of the β-(1→4) glycosidic bonds between the C1–C4 cellulose carbons releasing β-D-glucose monomers to be fermented into bioethanol. In the acid hydrolysis step, sulfuric acid of concentration 1127 gL−1 was used. After the experimental analyses performed, it could be observed that in acid hydrolysis, treatments using 70 mL and 80 mL of sulfuric acid did not differ statistically in relation to glucose production. However, by increasing the volume of acid to 90 mL, there was an increase in the production of fermentable sugars into bioethanol, 63.7 %, which began decreasing when adding acid above 93 mL, because the excess of acid also caused the degradation of sugars into 5-hydroxymethylfurfural (HMF); and in the treatment of 100 mL there was a higher production of HMF. The production of bioethanol proved to be competitive after the fermentation of the sample from the 90 mL treatment with a production of 103.7 L of bioethanol/ton of wood, in addition to being beneficial to the process as a whole with the co-production of furfural, 28.8 kg of furfural ton−1 of wood, and commercial lignin, 428.3 kg of lignin per ton of wood, precursors to various chemicals such as resins, coatings and inks.
Modelling and graphing the Wi-Fi wave field using the shape function
Authors: Trang ThanhTrung , Pham ThanhLong , Hu Yueming , Li Weiguang , Lin Shoujin
Published: September 2022

This article deals with modelling the Wi-Fi wave field, which is not visible to the naked eye, into a mathematical structure for assigning colours to observe the wave strength change compared to the source layout’s location correlation of obstacles in the survey environment. The shape function is used as a tool in modelling combined with finite sample measurement data to determine the basic parameters of the shape function. These will allow the wave field to be modelled using two techniques: the theoretical shape function and the experimental shape function. The measuring tool used in the article is the Wi-Fi Analyzer App that runs on a smartphone. The colour-assigned representation of an invisible field such as a wave will help select the signal maximal or minimization positions most beneficial to the user. The proposal is easily applied in the wave field and other quantities such as temperature, light, and concentration with similar techniques.
Main group cyanides: from hydrogen cyanide to cyanido-complexes
Authors: Schulz Axel , Surkau Jonas
Published: September 2022

Homoleptic cyanide compounds exist of almost all main group elements. While the alkali metals and alkaline earth metals form cyanide salts, the cyanides of the lighter main group elements occur mainly as covalent compounds. This review gives an overview of the status quo of main group element cyanides and cyanido complexes. Information about syntheses are included as well as applications, special substance properties, bond lengths, spectroscopic characteristics and computations. Cyanide chemistry is presented mainly from the field of inorganic chemistry, but aspects of chemical biology and astrophysics are also discussed in relation to cyano compounds.
Radiation error of air temperature measurements: Minimization of the error by a new reference system and comparison with conventional measurement systems, diurnal and annual variation of their errors as a function of radiation and wind speed
Authors: Miegel Konrad , Fröhlich Thomas , Pätz Joachim
Published: September 2022

The measurement of air temperature is associated with inaccuracies resulting from radiation errors. Liquid thermometers and automatic sensors are therefore housed in screens. Mechanical ventilation also helps to increase the accuracy of readings. Nonetheless, temperature measurements are not completely accurate. This spurred the development of a measuring system that features improved radiation protection and a modified mechanical ventilation system through a new type of screen. Parallel measurements with this new measurement system and two conventional screens of multiple plastic cones were taken at a location in north-east Germany with a temperate climate. Of the two traditional screens, one was ventilated and the other not. Based on previous findings concerning the seasonality of radiation errors, our analysis of their dependency on global radiation and wind speed was focused on the months of May to August, when global radiation is at its strongest. It was found that the not insignificant differences in

Δ
T

\Delta T

display a characteristic diurnal variation. With the new measurement system, in comparison with the two conventional measurung systems, the average air temperature of the four surveyed months during daylight hours was 0.43 K and 0.58 K lower. The differences in

Δ
T

\Delta T

are greatest not in the middle of the day but when the sun is low in the sky, as radiation is then reflected into the screen. The findings contribute to the understanding of the temporal variability of radiation errors in modern weather stations in dependence on global radiation and wind speed. The technical innovations presented here allow radiation errors to be largely avoided.
Ketamine alleviating depressive-like behaviors is associated with regulation of nNOS–CAPON–Dexras1 complex in chronic unpredictable mild stress rats
Authors: Shen Yiwei , Lv Feng , Min Su , Hao Xuechao , Yu Jian
Published: September 2022

Background

A growing number of studies have demonstrated that ketamine induces rapid and sustained antidepressant action. Neuronal nitric oxide synthase (nNOS) signaling has been explored for the treatment of neuropsychiatric disorders for decades. But the effect of ketamine on nNOS signaling is poorly understood. The aim of the present study was to investigate the effect of ketamine on nNOS signaling in a chronic unpredictable mild stress (CUMS) model of depression.

Methods

Forty-eight rats were randomly divided into four groups: the control group of healthy rats (group C), the healthy rats treated with ketamine 10 mg/kg for 3 days (group CK), the rats model of stress-induced depression group (group D), and the depressed group treated with ketamine 10 mg/kg for 3 days (group DK). The sucrose preference test and open field test were used to assess behavioral changes. Immunohistochemistry, immunofluorescence, and real-time PCR analysis were carried out to measure the expression of nNOS, CAPON, and Dexras1 in the prefrontal cortex (PFC) of the CUMS rats.

Results

Compared with healthy rats, the total distance traveled, the rearing counts, the sucrose preference percentage (SPP), and CAPON and Dexras1 expression in the PFC significantly decreased, while nNOS expression increased in CUMS rats. After treating with ketamine, the total distance traveled, the rearing counts, the SPP, and CAPON and Dexras1 expression significantly increased, while nNOS expression significantly decreased.

Conclusion

The results indicated that ketamine improved the depressive behavior of rats, which may be related to the reduced nNOS expression and enhanced CAPON and Dexras1 expression.
Optimization Algorithm of Reinforcement Point Location of New Lightweight Concrete Material for Building Exterior Wall
Authors: Gao Jingyang
Published: September 2022

Current methods for predicting the location of reinforced concrete materials neglect the precise division of material damage areas, resulting in poor prediction accuracy of the location of reinforced concrete. Therefore, a new optimization algorithm for the location of reinforcing points of new lightweight concrete materials for building exterior walls is proposed. The damage area of lightweight concrete is divided into several zones by using the precise threshold method. Based on the least squares support vector machine, the crack location on the surface of the new lightweight concrete wall is predicted. By solving the coordinates of each point of the triangle, the active reinforcement of the surface cracks of the new lightweight concrete wall materials is realized. The experimental results show that the proposed method takes less time and the prediction accuracy of the reinforced point position of the new lightweight concrete material is higher.
The Possibility of Producing Uniform Nanofibers from Blends of Natural Biopolymers
Authors: Abdulkadhim Mushreq Kareem , Habeeb Salih Abbas
Published: September 2022

This study was designed for the fabrication, characterization, and optimization of electrospinning blending three natural biopolymers including gelatin:chitosan:sodium alginate (G:CS:SA) solutions. Series of pure gelatin, 80:10:10, 60:20:20, 40:30:30, and 20:40:40 ratios of blends (G:CS:SA) were dissolved in aqueous acetic acid. The effects of solution property parameters blends were investigated through evaluation of the electrical conductivity, viscosity, and surface tension. The morphological properties of bio-nanofibers were studied using field-emission scanning electron microscopy to determine the diameter, bead formation, and the nanofiber distribution. The results showed that the increase in the percentage ratio of CS with SA higher than 40 % in G:CS:SA caused a decrease in polymer viscosity, average fiber diameter, and bead formation. The nanofibers produced from blending ratio 80:10:10 G:CS:SA had a uniformity and low numbers of bead formation. On the other hand, X-ray diffraction showed a higher crystallinity percentage and crystalline size for the aforementioned ratio; in addition, the Fourier-transform infrared showed interactions among the molecules of G, CS, and SA in nanofibers.
ENTREVISTA COM ANNE-MARIE CHARTIER
Authors: Peres Eliane
Published: September 2022

Em comemoração aos 30 anos de Cadernos de Educação, a Revista publica uma entrevista com umaimportante pesquisadora francesa dos temas ligados ao ensino da leitura e da escrita, a professora Anne-Marie Chartier.
O ENSINO DA ESCRITA ALFABÉTICA NO FINAL DA EDUCAÇÃO INFANTIL
Authors: Gomes de Morais Artur , Da Silva Alexsandro
Published: September 2022

Este artigo analisa comparativamente as prescrições de currículos nacionais de seis países (Brasil, Portugal, México, Espanha, Canadá e França) para o ensino da notação alfabética na Educação Infantil. O estudo, desenvolvido por meio da pesquisa documental e da análise de conteúdo, evidenciou que três dos seis currículos (Portugal, França e Canadá) assumem, de modo explícito, o direito de as crianças menores de seis anos viverem, na escola, experiências de reflexão sobre a escrita, a partir das quais possam ampliar seus conhecimentos sobre o sistema de notação alfabética, sem que isto implique antecipar o ensino sistemático de relações fonema-grafema.
Lack of L-type amino acid transporter 2 in murine thyroid tissue induces autophagy
Authors: Venugopalan Vaishnavi , Rehders Maren , Weber Jonas , Rodermund Lisa , Al-Hashimi Alaa , Bargmann Tonia , Golchert Janine , Reinecke Vivien , Homuth Georg , Völker Uwe , Verrey Francois , Kirstein Janine , Heuer Heike , Schweizer Ulrich , Braun Doreen , Wirth Eva K , Brix Klaudia
Published: September 2022

Proteolytic cleavage of thyroglobulin (Tg) for thyroid hormone (TH) liberation is followed by TH release from thyroid follicles into the circulation, enabled by TH transporters. The existence of a functional link between Tg-processing cathepsin proteases and TH transporters has been shown to be independent of the hypothalamus–pituitary–thyroid axis. Thus, lack of cathepsin K, combined with genetic defects in the TH transporters Mct8 and Mct10, that is the Ctsk−/−/Mct8−/y/Mct10−/− genotype, results in persistent Tg proteolysis due to autophagy induction. Because amino acid transport by L-type amino acid transporter 2 (Lat2) has been described to regulate autophagy, we asked whether Lat2 availability is affected in Ctsk−/−/Mct8−/y/Mct10−/− thyroid glands. Our data revealed that while mRNA amounts and subcellular localization of Lat2 remained unaltered in thyroid tissue of Ctsk−/−/Mct8−/y/Mct10−/− mice in comparison to WT controls, the Lat2 protein amounts were significantly reduced. These data suggest a direct link between Lat2 function and autophagy induction in Ctsk−/−/Mct8−/y/Mct10−/− mice. Indeed, thyroid tissue of Lat2−/− mice showed enhanced endo-lysosomal cathepsin activities, increased autophagosome formation, and enhanced autophagic flux. Collectively, these results suggest a mechanistic link between insufficient Lat2 protein function and autophagy induction in the thyroid gland of male mice.
Preparation of cellulosic air filters with controllable pore structures via organic solvent-based freeze casting: The key role of fiber dispersion and pore size
Authors: Ma Shanshan , Zhang Meiyun , Yang Bin , Song Shunxi , Nie Jingyi , Lu Peng
Published: September 2022

Green and biodegradable cellulose filters with controlled designer pore structures were prepared using organic solvent-based freeze casting. In this paper, the relationship between the different freeze media, including ethanol, isopropanol, and tertiary-butyl alcohol, and the microstructure of the porous filters was investigated. The results of the pore size distribution indicated that the pore channel size decreased remarkably when organic solvents were used as the freezing media. Moreover, the filters showed high filtration efficiencies, up to 99.70% and 99.66% for 0.5 µm and 0.3 µm particles, respectively, under a pressure drop of 180 Pa and at 32 L·min-1 flow rate. The fabrication of cellulosic filters would not only make it a promising candidate for capturing fine particulate matter, but also provide a versatile approach to regulate and design a porous structure for materials applied in various fields.
Effect of the Ca2+ concentration on anaerobic digestion and microbial communities of granular sludge
Authors: Wang Zhiwei , Zhu Cancan , Yi Min , Yang Zhenzhen , Feng Qiming , Wang Shuangfei
Published: September 2022

The effects of substrate Ca2+ concentration were studied relative to the anaerobic digestion and microbial community structure of anaerobic granular sludge. In the treatment of papermaking wastewater by anaerobic granular sludge, the cumulative gas production was maximum at a Ca2+ concentration in the substrate of 120 mg/L, whereas it was the lowest at a concentration of Ca2+ in the substrate of 4000 mg/L. A high Ca2+ concentration in the substrate (≥1200 mg/L) will cause the pH of the fermentation broth to decrease during the fermentation process, which is not conducive to the anaerobic fermentation of the methanogenic process, resulting in unsatisfactory anaerobic digestion of the granular sludge. In addition, when the Ca2+ concentration was below 200 mg/L, the abundance of the important bacterial family Ruminococcaceae (rumen bacteria) in the anaerobic fermentation hydrolysis stage was drastically reduced and methane gas production increased. When the Ca2+ concentration was above 200 mg/L, the abundance of Anaerolineaceae (Anaerobic Streptomyces), which supplies organic acids, was substantially reduced. The methane gas production decreased as the Ca2+ concentration increased. Thus, the results showed that when the concentration of Ca2+ was above 200 mg/L, the methanogenic activity of granular sludge decreased.
Litoesculturas del Periodo Formativo en Yambrasbamba, cuenca media del Imaza (Bongará-Amazonas)
Authors: Villar Quintana Anthony Alex
Published: September 2022

Actualmente, se observan distintas muestras de sillares prehispánicos finamente tallados en Yambrasbamba (Bongará-Amazonas), los cuales no cuentan con algún estudio arqueológico hasta el momento. Tres de estos cuentan con grabados figurativos en alto relieve, cuya iconografía es diagnóstica del Periodo Formativo. Asimismo, exploramos algunas posibilidades en relación a su funcionalidad y la cosmovisión de las sociedades que las elaboraron; a lo cual se suman algunas reflexiones acerca de la implicancia de este y otros sitios, de las cuencas del Imaza y Utcubamba, en las redes te interacción interregional durante el Formativo, basándonos principalmente en comparaciones iconográficas con otros sitios de este periodo.
Pinedo Pérez, Omar (Ed.). La arqueología de Lima Norte
Authors: Querevalú Ulloa José Samuel
Published: September 2022

El presente texto es el producto del Primer Simposio de Lima Norte que se realizó el 10 de agosto del 2018 en el distrito de Los Olivos, en el cual el autor de la presente reseña también tuvo la oportunidad de asistir. Antes de tocar individualmente los escritos que conforman este libro, vale señalar los motivos del editor para realizar el esfuerzo, no sólo de organizar un evento cultural presencial (con la colaboración de la Municipalidad de Los Olivos y la UCSS), sino además publicar lo expuesto aquel día, hecho que ya no es tan frecuente respecto a otros eventos académicos sobre zonas o temas específicos.
Rosaura Andazabal (1961-2021): una retrospectiva de su labor académica en el SHRA-UNMSM
Authors: Soria Casaverde María Belén
Published: September 2022

Agradezco a los coordinadores de la Revista del ISHRA por haberme invitado a rememorar algunos aspectos de la trayectoria académica de la historiadora Rosaura Petronila Andazabal Cayllahua. Ella nació en Ayacucho, en 1961. Fue hija de don Menelio Andazabal y doña Maximiliana Cayllahua. Fuimos colegas de trabajo en el Seminario de Historia Rural Andina - SHRA, centro de investigación fundado en 1966 por nuestro querido maestro, el historiador Dr. Pablo Macera. Rosaura sentó presencia en el SHRA desde 1985, hasta su sentida partida en el 2021. Cumplió 36 años de labor ininterrumpida y desarrolló una amplia producción bibliográfica y curaduría de exposiciones. Me complace saber que la presente revista anexará en su parte final un listado de su producción bibliográfica, por lo que me centraré en resaltar algunos aspectos de su formación profesional.
Confección de férulas de descarga personalizadas por CAD-CAM
Authors: Anitua Eduardo
Published: September 2022

La elaboración de férulas de descarga con la utilización de la técnica convencional, basada en la mezcla de un monómero y polímero con el posterior curado de la mezcla, puede dejar restos de monómero que generen reacciones de hipersensibilidad en algunas personas sensibles a estos químicos. Así, el uso de la tecnología CAD-CAM (Diseño Asistido por Ordenador - Fabricación Asistida por Ordenador), puede mejorar el ajuste y confort relacionado con el uso del dispositivo por el paciente. En el siguiente artículo se presenta un método de elaboración de férulas basado en esta tecnología.
Determinación del periodo de retiro de enrofloxacina en cuyes (Cavia porcellus)
Authors: Ortiz G. Tomás , Lucas L. J. Raúl , Aybar E. Mariel , Angulo-Tisoc José , Ramos D. Daphne
Published: September 2022

El objetivo del estudio fue determinar el periodo de retiro de enrofloxacina en cuyes (Cavia porcellus). Se utilizaron 51 cuyes (25 hembras y 26 machos) de la raza Perú de una granja ubicada en el distrito de Maranganí (Cusco, Perú). Para ello, se administró enrofloxacina al 10%, vía oral, a razón de 10 mg/kg (0.1 ml/kg PV) cada 24 horas por un periodo de 10 días. Inmediatamente después de la última administración del antibiótico (hora 0), tres cuyes fueron seleccionados en forma aleatoria y sacrificados cada dos horas hasta las 32 horas del retiro del fármaco, tomándose muestras del músculo diafragma. El análisis y cuantificación de los residuos del antibiótico en el diafragma se realizó empleando el kit comercial Max Signal® Enrofloxacin ELISA Kit. La concentración máxima de enrofloxacina (1425 ± 53.4 µg/kg) se determinó a las 12 horas del retiro, descendiendo hasta 80.8 ± 6 µg/kg a las 28 h, valor por debajo de 100 µg/kg considerado como límite máximo de referencia. Bajo las condiciones de este estudio, se sugiere un periodo de retiro de dos días para cuyes tratados con enrofloxacina.
Comparison of Early-Onset Sepsis Risk-Stratification Algorithms in Neonates in a Kenyan Nursery
Authors: Fileccia Lindsey , Wood Tristan , Guthrie Alyssa , Ronoh Cynthiah , Sleeth Clark , Kamath-Rayne Beena D. , Liu Chunyan , Schaffzin Joshua K. , Rule Amy RL.
Published: September 2022

BACKGROUND AND OBJECTIVES

Risk stratification algorithms (RSAs) can reduce antibiotic duration (AD) and length of stay (LOS) for early-onset sepsis (EOS). Because of higher EOS and antibiotic resistance rates and limited laboratory capacity, RSA implementation may benefit low- and middle-income countries (LMIC). Our objective was to compare the impact of 4 RSAs on AD and LOS in an LMIC nursery.

METHODS

Neonates <5 days of age admitted for presumed sepsis to a Kenyan referral hospital in 2019 (n = 262) were evaluated by using 4 RSAs, including the current local sepsis protocol (“local RSA”), a simplified local protocol (“simple RSA”), an existing categorical RSA that uses infant clinical examination and maternal risk factors (CE-M RSA) clinical assessment, and the World Health Organization’s Integrated Management of Childhood Illness guideline. For each RSA, a neonate was classified as at high, moderate, or low EOS risk. We used к coefficients to evaluate the agreement between RSAs and McNemar’s test for the direction of disagreement. We used the Wilcoxon rank test for differences in observed and predicted median AD and LOS.

RESULTS

Local and simple RSAs overestimated EOS risk compared with CE-M RSA and the Integrated Management of Childhood Illness guideline. Compared with the observed value, CE-M RSA shortened AD by 2 days and simple RSA lengthened AD by 2 days. LOS was shortened by 4 days by using CE-M RSA and by 2 days by using the local RSA.

CONCLUSIONS

The local RSA overestimated EOS risk compared with CE-M RSA. If implemented fully, the local RSA may reduce LOS. Future studies will evaluate the prospective use of RSAs in LMICs with other interventions such as observation off antibiotics, biomarkers, and bundled implementation.
Development and validation of interpretable machine learning models for inpatient fall events and electronic medical record integration
Authors: Shim Soyun , Yu Jae Yong , Jekal Seyong , Song Yee Jun , Moon Ki Tae , Lee Ju Hee , Yeom Kyung Mi , Park Sook Hyun , Cho In Sook , Song Mi Ra , Heo Sejin , Hong Jeong Hee
Published: September 2022

Objective Falls are one of the most frequently occurring adverse events among hospitalized patients. The Morse Fall Scale, which has been widely used for fall risk assessment, has the two limitations of low specificity and difficulty in practical implementation. The aim of this study was to develop and validate an interpretable machine learning model for prediction of falls to be integrated in an electronic medical record (EMR) system.Methods This was a retrospective study involving a tertiary teaching hospital in Seoul, Korea. Based on the literature, 83 known predictors were grouped into seven categories. Interpretable fall event prediction models were developed using multiple machine learning models including gradient boosting and Shapley values.Results Overall, 191,778 cases with 272 fall events (0.1%) were included in the analysis. With the validation cohort of 2020, the area under the receiver operating curve (AUROC) of the gradient boosting model was 0.817 (95% confidence interval [CI], 0.720–0.904), better performance than random forest (AUROC, 0.801; 95% CI, 0.708–0.890), logistic regression (AUROC, 0.802; 95% CI, 0.721–0.878), artificial neural net (AUROC, 0.736; 95% CI, 0.650–0.821), and conventional Morse fall score (AUROC, 0.652; 95% CI, 0.570–0.715). The model’s interpretability was enhanced at both the population and patient levels. The algorithm was later integrated into the current EMR system.Conclusion We developed an interpretable machine learning prediction model for inpatient fall events using EMR integration formats.
La coca convoca: autonomía ante la acumulación en Colombia
Authors: Dest Anthony
Published: September 2022

Este artículo analiza un fenómeno relativamente nuevo en el norte del Cauca: la expansión masiva de los cultivos de coca. Tras décadas de intensas campañas de erradicación forzada respaldadas por el gobierno de Estados Unidos, la llamada "guerra contra las drogas" ha fracasado en su supuesto objetivo. En el norte del Cauca los cultivos de coca están asociados con una ola de colonización de cultivadores desplazados por el Plan Colombia que llevó consigo lo que algunos habitantes de la región llaman la “anticultura de la coca” asociada con nuevas formas de consumo, violencia y una relación extractiva con la tierra. Esta etnografía explora el poder de la coca para transformar relaciones sociales y económicas, también revela cómo se reproducen las desigualdades estructurales de la sociedad colombiana en las regiones donde se cultiva la planta.
Contar en tiempos de fusiles: aproximaciones a la escritura etnográfica
Authors: Parra Jhon Alberto
Published: September 2022

Para contar el mundo hay que aprender a sentirlo, escucharlo, verlo e imaginarlo. La imaginación en sí misma es una forma de narrar y de reivindicar otros espectros de realidad; lo que le otorga un carácter identitario a lo contado es cómo la imaginación logra conjugarse con las palabras y de paso delimita esa poética que hay en cada forma de estructurar aquello que se quiere gritar con símbolos. La antropología en Colombia ha tenido que aprender a escribir en los ritmos que cada partitura de violencia ha sabido componer: una etnografía de la violencia va más allá de nombrar duelos.
Combinatorial description around any vertex of a cubical n-manifold
Authors: Hinojosa Gabriela , Valdez Rogelio
Published: September 2022

We say that a topological space N is a cubical n-manifold if it is a topological manifold of dimension n contained in the n-skeleton of the canonical cubulation of Rn+2. For instance, any smooth n-knot Sn → Rn+2 can be deformed by an ambient isotopy into a cubical n-knot. An open question is the following: Is any closed, oriented, cubical n-manifold N in Rn+2, n > 2, smoothable? If the response is positive, we could give a discrete description of any smooth n-manifold; in particular, if we can stablish that for smooth n-knots, that fact can be useful to define invariants. One of the main dificulties to answer the above question lies in the understanding of how N looks at each vertex of the canonical cubulation. In this paper, we analyze all possible combinatorial behaviors around any vertex of any cubical manifold of dimension n, via the study of the cycles on the complete graph K2n.
New linearization method for nonlinear problems in Hilbert space
Authors: Bouazila Nada , Guebbai Hamza , Merchela Wassim
Published: September 2022

In this paper, we build a Newton-like sequence to approach the zero of a nonlinear Fréchet differentiable function defined in Hilbert space. This new iterative sequence uses the concept of the adjoint operator, which makes it more manageable in practice compared to the one developed by Kantorovich which requires the calculation of the inverse operator in each iteration. Because the calculation of the adjoint operator is easier compared to the calculation of the inverse operator which requires in practice solving a system of linear equations, our new method makes the calculation of the term of our new sequence easier and more convenient for numerical approximations. We provide an a priori convergence theorem of this sequence, where we use hypotheses equivalent to those constructed by Kantorovich, and we show that our new iterative sequence converges towards the solution.
Stability analysis of a fractional virotherapy model for cancer treatment
Authors: Tavoni Robinson , A. Mancera Paulo F. , Camargo Rubens F.
Published: September 2022

This paper presents a stability analysis of a differential equations model related to the cancer treatment with an oncolytic virus in its classical and fractional version via Caputo derivatives. Numerical simulations of three possible scenarios are presented and support the discussions on the advantages of using fractional modeling.
A self-contained guide to Frécon's theorem
Authors: Corredor Luis Jaime , Deloro Adrien
Published: September 2022

A streamlined exposition of Frécon's theorem on non-existence of bad groups of Morley rank 3. Systematising ideas by Poizat and Wagner, we avoid incidence geometries and use group actions instead; the proof becomes short and completely elementary.
Obtención de bioproductos a partir de residuos del beneficio húmedo del café (pulpa)
Authors: Triviño Pineda Jairo Smith , Contreras García José , Amorocho Cruz Claudia Milena , Sánchez Ramírez Javier Eduardo
Published: September 2022

Este trabajo presenta los resultados obtenidos a escala de laboratorio para el aprovechamiento de la pulpa de café (residuos), en el proceso de beneficio húmedo aplicando el concepto de biorrefinería. Los resultados mostraron que es posible tratar este residuo mediante procesos fermentativos y obtener bioetanol separado por medio de la destilación simple con un contenido en alcohol entre 3,85% al 6,90% por cada 250ml de biomasa tratada en condiciones ambientales. Se observó en todos los ensayos que una variable importante es el tiempo de fermentación y la estructura inicial del residuo ya que esto influye sobre el rendimiento obtenido en términos del bioalcohol producido. Este trabajo forma parte del estudio preliminar para la implementación del concepto de biorrefinería a los residuos generados en el beneficio húmedo del café. La búsqueda de alternativas que permitan el aprovechamiento de los residuos del café constituye una problemática actual. Estos residuos al no ser tratados, por lo general son vertidos a las fuentes hídricas y en ocasiones utilizados como enmiendas agrícolas en los cultivos, lo cual puede causar graves problemas de contaminación. Por este motivo es necesario realizar investigaciones en este campo que permitan su tratamiento o aprovechamiento integral.
Bata o seu koo
Authors: Oliveira Luciana Xavier de
Published: September 2022

Dentro de um projeto de pesquisa mais amplo voltado para o estudo sobre cenas musicais negras desenvolvidas no atual contexto urbano brasileiro, este artigo resulta de observações desenvolvidas a respeito da festa Batekoo, realizada na cidade de São Paulo. A partir de um relato de inspiração etnográfica, o texto apresentado busca discutir os sentidos, estéticas e valores postos em circulação a partir dessa festa, a fim de ampliar as discussões sobre as reconfigurações das identidades raciais observando o consumo da música popular, a configuração de novos estilos e as performatizações de gênero como estratégias reflexivas para a negociação de subjetividades e tensionamento das relações de poder. Busca-se, dessa forma, apresentar novos caminhos teóricos para a compreensão das dinâmicas raciais, reconhecendo nas mediações das produções culturais negras juvenis diferentes dramatizações de linguagens e novos projetos estéticos e identitários performados no espaço da festa que ensejam diferentes exercícios estéticos, comunicativos e políticos na cidade contemporânea.
Integração das tecnologias da informação e comunicação no espaço escolar e sua interlocução com o projeto político pedagógico: uma revisão sistemática da literatura
Authors: De Lima Brito Mateus , Lima Vasconcelos Francisco Herbert , Marçal Edgar
Published: September 2022

Este artigo tem como objetivo analisar trabalhos que tratam sobre a integração das Tecnologias da Informação e Comunicação (TICs) no espaço escolar e sua interlocução com o Projeto Político Pedagógico (PPP). A pesquisa trata-se de uma Revisão Sistemática da Literatura (RSL) com natureza quanti-qualitativa na metodologia. Como resultado, constatou-se que ainda existe uma carência de pesquisas que relacionem as tecnologias ao PPP das escolas. Verificou-se a relevância do uso das TICs e observou-se que as escolas citam sobre as TICs, mas não descrevem como seria a integração das tecnologias nos processos educacionais.
Improving Student's Reasoning Ability Through The Tahfizh Al-Qur’an Program
Authors: Chalida Sri , Syafruddin Syafruddin , Pinto Nandi , Fakhruddin Muhammad Irhash
Published: September 2022

Teaching tahfizh al-Quran is one way to build student competence to do reasoning in and memorizing the Al-Qur’an. Given the changes in vision and mission as stated in the competency-based curriculum, it is necessary to make concrete efforts to prepare and make its implementation successful. This study aims to identify the teaching method of tahfizh al-Quran  at the Tafsir Hadis Major, to explain the strategy of optimally developing tahfizh al-Qur'an so that it can improve students' reasoning abilities and identify the level of students' reasoning ability after participating in the tahfizh al-Qur'an program at the Tafsir Hadis Major. This study is a development activity carried out in collaboration between students and lecturers to conceptually design the design of teaching materials based on experience and existing conditions. These two stages will always be accompanied by a process of evaluation and reflection to improve the designs developed. This research shows that first; the sima'i method is a method that is widely used by students in memorizing the Qur'an, secondly; the strategy of fostering tahfizh al-Quran   should be done with the muraja'ah method, Third; From the results of the calculation of the student's reasoning ability test scores, the average score of students' reasoning abilities in the high category was 48.82, the average category was 41.06, and the low category has obtained an average of 39. These different average gains indicate that the levels of students' reasoning abilities are different.
METODE EXPONENTIAL SMOOTHING WITH TREND PADA AKURASI PERAMALAN KEBAKARAN HUTAN DAN LAHAN
Authors: Pratiwi Merina , Syarief Amiroel Oemara
Published: September 2022

Kebakaran hutan dan lahan yang terjadi membuat dampak global mengakibatkan gangguan pernapasan dan mengganggu aktivitas sehari-hari. Pemerintah sedang berupaya mengatasi permasalahan tersebut, namun belum dapat sepenuhnya menentukan area kebakaran hutan dan lahan. Penelitian ini bertujuan untuk meramalkan kebakaran hutan dan lahan menggunakan metode exponential smoothing with trend. Hasil penelitian menunjukkan bahwa akurasi peramalan dengan metode Exponential Smoothing with Trend  menggambarkan tingkat kesalahan yang cukup berdasarkan kriteria, dengan memiliki MAPE yang lebih kecil sebesar 30,99 sehingga metode ini merupakan salah satu metode peramalan yang cocok untuk meramalkan luas kebakaran hutan dan lahan tahun 2023 dengan luas sebesar 167,487 Hektare. Hasil perhitungan ini dapat dijadikan sebagai dasar kebijakan dalam pemberian informasi dan penanganan dini luas daerah yang terkena dampak kebakaran hutan dan lahan pada tahun 2023.
A importância da religiosidade e espiritualidade durante o processo de saúde-doença dos pacientes hospitalizados
Authors: De Sousa Silva Natália Cristina
Published: September 2022

O fenômeno da religiosidade e da espiritualidade tem alterado de maneira significativa o sentido e o significado da doença para aquele que sofre. Mesmo que não implique na remoção dos sintomas que causam a dor, modifica-se a percepção dos significados quanto à doença. Parte-se da hipótese de que a religiosidade e a espiritualidade atribuem sentido à vida mesmo diante do sofrimento, pois criam uma rede de apoio, que deve ser mobilizada de maneira conjunta às práticas médicas tradicionais. Diante desse cenário, a partir de uma pesquisa bibliográfica, este estudo tem como objetivo geral discutir sobre os impactos da religiosidade e espiritualidade no processo saúde-doença. Visa-se demonstrar que a religiosidade e a espiritualidade constituem as crenças e percepções do indivíduo quanto à doença e, desse modo, não podem ser excluídas do tratamento terapêutico dos pacientes.
Penyelenggaraan Umrah Dalam Perspektif Hukum Perlindungan Konsumen Pasca PMA No. 8 Tahun 2018
Authors: Suwandono Agus , S. Dajaan Susilowati
Published: September 2022

To give better protection to the prospective participant of the Islamic pilgrimage (‘umrah), the Minister of Religious Affairs has just added consideration to the Consumer Protection Law in enacting the Minister of Religious Affairs’ Regulation No. 8 of 2018. According to the Consumer Protection Law, this research studies the qualification of the Islamic Pilgrimage’s prospective participant and organizer. It also looks at the recourse obtained by the prospective participants from the perspective of the consumer protection law, after the enactment of the Minister of Religious Affairs’ Regulation No. 8 of 2018. This research is using a juridical-normative approach by specifying the study in a descriptive-analytical manner. The result shows that the Consumer Protection Law’s provision qualifies the prospective participant of Islamic pilgrimage (‘umrah) as a consumer, whereby its organizer as a business actor. From the perspective of the Consumer Protection Law, the enactment of the Minister of Religious Affairs’ Regulation No. 8 of 2018 has not yet fully safeguarded the prospective participant’s interests. In conclusion, after bearing into mind that their rights have not yet wholly fulfilled, particularly at the time of departure cancellation.

 

Pemberlakuan PMA No. 8 Tahun 2018 dengan mempertimbangan ketentuan Undang-Undang Perlindungan Konsumen merupakan hal baru diharapkan dapat lebih memberikan perlindungan  terhadap calon jemaah umrah. Penelitian ini mengkaji bagaimanakan kualifikasi calon jemaah umrah serta PPIU berdasarkan Undang-Undang Perlindungan Konsumen serta bagaimanakah perlindungan calon jemaah umrah dalam perspektif perlindungan konsumen pasca pemberlakuan PMA No. 8 Tahun 2018. Penelitian ini merupakan penelitian yurudis normatif dengan spesifikasi penelitian deskriptif analitis. Hasil penelitian menunjukkan bahwa calon jemaah umrah dapat dikualifikasikan sebagai konsumen dan PPIU juga dapat dikualifikasikan sebagai pelaku usaha berdasarkan Ketentuan Undang-Undang Perlindungan Konsumen. Perlindungan calon jemaah umrah dalam perspektif perlindungan konsumen pasca pemberlakuan PMA No. 8 Tahun 2018 belum sepenuhnya memberikan perlindungan bagi calon jemaah umrah, mengingat pemenuhan akan hak-hak para calon jemaah umrah tidak dapat terpenuhi terlebih dalam hal terjadinya  gagal berangkatnya calon jemaah umrah.
ARCHIVING AND LANGUAGE DOCUMENTATION
Authors: Epps Patience , Kung Susan Smythe , Moore Denny , Labrada Jorge Rosés , O’Hagan Zachary , Brandao Ana Paula
Published: September 2022

This article is derived from a conference at the ABRALIN ao vivo, held online, in 2020. The goal is to discuss the benefits and challenges associated with archiving in language documentation considering our accumulated knowledge as scholars who are deeply involved in administering, contributing to, and drawing on language archives, with an emphasis on the indigenous languages of Latin America. We focus in particular on the relevance of language archiving in Brazil, and its significance for scholars, community members, and other stakeholders.
Brazilian’s Foreign Policy and Health (1995-2010): A policy analysis of the Brazilian Health Diplomacy – from Aids to ‘Zero Hunger’
Authors: Almeida Celia Maria de , Lima Thaisa Santos , Campos Rodrigo Pires de
Published: September 2022

This article examines how health entered Brazilian foreign policy between 1995 and 2010 and the factors that allowed it to support the country's international presence. This issue is rarely examined in the literature on Brazilian health diplomacy. We analyze the specificities of this process within a policy analysis approach. By drawing on literature review, document analysis and key-actor interviews, we revise policies that were triggered by far-reaching and complex historical processes of change in Brazil. The article points to significant interrelationships between foreign policy and social policy, including health. Only during Lula governments (2003-2010) did health actually enter the foreign policy agenda, in significant support of Brazil’s growing international presence. Brazil’s internationalisation of its domestic policies connected with South-South cooperation exerted a central role. These developments were made possible by the activism and commitment of a variety of State and non-State actors who acted on at least two lines: national and transnational advocacy, and coordinated activities of Brazilian diplomats and government representatives, in collaboration with civil society activists. Institutional arrangements shifted in different conjunctures and were adjusted in a process permanently prone to conflicts and moves.
Greener and scalable synthesis of N-methyl imines using a sustainable functional polymer
Authors: Mihankhah Peyman , Khaligh Nader Ghaffari
Published: September 2022

N-Methyl imines, as simple Schiff bases, could be prepared using a more sustainable and greener system, including a 33 wt.% solution of methylamine in absolute ethanol, and poly(N-vinylimidazole) (PVIm) at room temperature within 45–60 min. PVIm is a biocompatible, biodegradable and water-soluble synthetic solid functional polymer. It was indicated that PVIm can act as a reagent with multiple tasks in this reaction, including (a) reducing activation energy and stabilizing the transition states through hydrogen bond acceptor sites and low acidity of C(2)–H and (b) dehydrating activity through trapping of the released water molecules as the association phase. Inexperienced chemists can handle it easily because it is solid and less toxic than conventional catalysts – that is, piperidine, pyridine or metal- or halogen-containing salts. Additionally, ethanol and PVIm could be recycled and reused in subsequent runs without any further purification. The regenerated PVIm demonstrated stable activity after several recycle runs. No changes were detected in its chemical structure, as confirmed by Fourier transform infrared and nuclear magnetic resonance spectrum analyses.
Protein adsorption on amino-acid-conjugated self-assembled molecule-modified SiO2 surfaces
Authors: Demirbüken Sezin Eren , Aktaş Bengü , Öncel Meftune Özgen Öztürk , Hür Deniz , Uzun Lokman , Garipcan Bora
Published: September 2022

Protein adsorption has a crucial effect on biocompatibility during the interaction of biomaterial surfaces and the biological environment. It is significant to understand and control the interactions among biomaterials and proteins for several biomedical applications. Surface engineering plays a significant role in determining biocompatibility by tuning the effects directly on proteins. In this study, amino acid (histidine and leucine) conjugated self-assembled molecules were synthesized and used to modify silicon dioxide (SiO2) surfaces to investigate protein adsorption behavior. Silicon dioxide surfaces were modified with (3-aminopropyl)triethoxysilane-conjugated histidine and leucine amino acids. Modified silicon dioxide surfaces were characterized by water contact angle measurements and X-ray photoelectron spectroscopy analysis. Protein adsorption (human serum albumin, fibrinogen and immunoglobulin G) on silicon dioxide-coated crystals was investigated in situ by using a quartz crystal microbalance (QCM) biosensor. From the results, model proteins showed different selectivities to the amino-acid-conjugated silicon dioxide-coated crystals depending on the type of the amino acid and concentration. Consequently, this controlled chemistry on the surface of biomaterials has a great potential to manipulate protein adsorption and enhance the biocompatibility of biomaterials for various biomedical applications.
Recent innovations in surface topography
Authors: Chambers Lily , Roach Paul , Shirtcliffe Neil
Published: September 2022

In this review, the authors provide a general review of current research themes where complex surface topography plays a role. Recent innovations and research possibilities have opened up using modern microtopography creation techniques. This review considers a large range of themes in limited depth to provide an introduction and to illustrate how broad the field is and, to those already working in the area, to help gain a broad perspective. Due to the breadth of scope, this review does not go into much depth into any given area. This review aims to provide a comprehensive understanding of and practical guidance on the modern use of micro- and nanotopography to control water; adhesion; wettability; biological adhesion, including implants, cell culture and biofouling; and directional fluid transport. The broad range of functionality is highlighted in the many interfacial interactions. However, the methods allowing economy of scale allowing these surfaces to be used commonly is still in development. To make this review more accessible, the authors have chosen to concentrate on open-access articles to cite.
Desarrollo de las competencias básicas de los estudiantes en el aprendizaje de lenguas extranjeras a través de métodos interactivos
Authors: Trofymenko Anastasiia A. , Hniedkova Olena H. , Tokarieva Olha V. , Lytvynko Oksana A. , Kravchenko Odarka O.
Published: September 2022

El objetivo del estudio fue sistematizar la experiencia mundial de comprensión del proceso de formación de competencias en el aprendizaje de una lengua extranjera utilizando métodos interactivos. Para ello, se realizó una evaluación objetiva de las competencias básicas a través de métodos interactivos. Los métodos y técnicas de adquisición de las competencias básicas requeridas que se han utilizado eficazmente en el proceso educativo se elaboraron como parte del desarrollo profesional y personal de los futuros especialistas. Se utilizó el método analítico-sintético, por medio de una encuesta; asimismo, se utilizó un método de modelado situacional; análisis cualitativo y cuantitativo; interpretación empírica estadística y matemática; y un análisis funcional de los resultados de la investigación. A partir de un análisis teórico de un problema científico, se desarrolló un modelo objetivo y subjetivo para diagnosticar el nivel de formación de competencias básicas de los estudiantes. El primer grupo de encuestados tenía un nivel suficiente de competencias básicas (364,1 puntos), que es del 73,8%. El segmento intelectual y creativo mostró la tasa más alta en la estructura de competencias - 75,1%. El segundo grupo de encuestados no lingüísticos mostró un nivel algo similar de Competencias Básicas (369,9 puntos = 75,8%), sin embargo, mostró una debilidad relativa del segmento socioemocional (53,5%). Se pueden realizar más investigaciones para identificar y desarrollar métodos de investigación para muchas competencias, teniendo en cuenta las características de edad de los estudiantes.