bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review of COVID-19 Vaccine Adverse Event Following Immunization Case Reports by four CARICOM Countries to VigiBase
Authors: Marin Danini
Published: July 2024

The World Health Organization declared COVID-19 a pandemic on 12 March 2020. One of the strategies to combat the pandemic was the development of novel COVID-19 vaccines. Once these vaccines were deployed, immunizations followed. The objective of this study was to identify the characteristics of case reports of adverse events following immunization (AEFIs) with COVID-19 vaccines based on Individual Case Safety Reports (ICSRs) in VigiBase, submitted by four CARICOM countries: Barbados, Haiti, Jamaica and St. Vincent and the Grenadines. A review of the publicly available data on AEFIs with COVID-19 vaccines based on ICSRs in VigiBase was conducted from March 1, 2021 to December 14, 2022. A total of 1,582 AEFI case reports were identified for this period. Most of these were non-serious events, involving persons under 65 years (84.9%), and females (74.1%); 19% were classified as serious events. The top age group reported for AEFIs in VigiBase were 18-44 years (46.6%). The most frequently reported reactions were headache (29.3%), pyrexia (19.3%), dizziness (19.3%). Altogether for the four countries, the AEFIs per 100,000 doses was 64.1 and 12.2 serious AEFIs per 100,000 doses. Recommended actions identified were strengthening national pharmacovigilance regulatory frameworks, establishing robust national pharmacovigilance centres, capacity building of professionals, enhancing communication with key stakeholders and consider relying in a regional pharmacovigilance system.
Análise de Enterobactérias em Emerita brasiliensis (Schmitt, 1935) Coletados na Praia de Balneário Rincão, Santa Catarina, Brasil
Authors: Boff Larissa de Aguiar , Quadros Rosiléia Marinho de
Published: July 2024

A pesquisa em questão teve como objeto de estudo o crustáceo Emerita brasiliensis, conhecido popularmente como “tatuíra”, e seu objetivo foi o de identificar a presença de enterobactérias em Emerita brasiliensis de ambiente natural no município de Balneário Rincão, sul de Santa Catarina, Brasil. Para isso, foram coletadas o total de 30 amostras de dois pontos distintos onde haviam indícios de despejos de efluentes. As amostras foram preparadas e inoculadas em água peptonada e, em seguida, semeadas em meio de cultura de MacConkey e TCBS (tiossulfato, citrato, bile sacarose), o primeiro sendo um meio específico para o isolamento e identificação de enterobactérias e o segundo para os microrganismos do gênero Vibrio. Houve crescimento bacteriano em 53,33% das amostras coletadas, sendo os seguintes microrganismos identificados: Enterobacter sp.; Escherichia coli; Klebsiella pneumoniae e Edwardsiella sp. No TCBS, houve crescimento em 16 meios, porém apenas duas eram de coloração esverdeada, sendo um indicativo de Vibrio parahaemolyticus. Contudo, o fato de algumas espécies patogênicas terem sido identificadas nas amostras coletadas, já é um possível indício de contaminação.
Smoking among children and adolescents as a modern multidisciplinary problem
Authors: Fayzullina R. M , Geppe N. A. , Sannikova A. V. , Shangareeva Z. A. , Kozhevnikova T. N. , Panchikhina O. Yu. , Arslanova O. A.
Published: July 2024

The prevalence of smoking, use of tobacco and nicotine-containing products among children and adolescents is a significant problem of our time. The continuing high prevalence of child and adolescent smoking and contradictory statistical data for certain regions of the Russian Federation determine the need to study this topic.

Purpose. To study the prevalence and risk factors of smoking among children and adolescents in the Republic of Bashkortostan.

 Material and methods. A one-stage continuous study oftobacco smoking among children aged 7 to 17 years was conducted using an anonymous voluntary online questionnaire of schoolchildren using the Google questionnaire form. 76 543 respondents took part in the study.

Results. The study showed that 2.5% of children and adolescents are smokers. More than 3/4 of them smoke daily, most of them prefer electronic cigarettes. Every fourth child is not motivated to quit smoking. Half of smoking children first try smoking at the age of 12–17 years, 1/3 — at the age of 10 years. The reasons for introducing children to smoking are the example of parents, friends and classmates, the availability of smoking products. Every third child who smokes feels a deterioration in their health. Every second child is open to communication with adults and is ready to listen to medical conversations.

Conclusion. To reduce the prevalence of smoking among children and adolescents, competent, scientifically based multidisciplinary work is needed with the introduction of regional multicomponent prevention programs.
Peculiarities of development and lesions of the central nervous system in late preterm newborns
Authors: Zhuravleva I. V. , Zyablova I. Yu. , Sarkisyan E. A. , Vorona L. D. , Dumova S. V. , Shabelnikova E. I. , Tulsky I. N. , Shumilov P. V.
Published: July 2024

The last weeks of pregnancy are a critical period of intrauterine development of the central nervous system. In late preterm infants born at gestational age 340/7 — 366/7 weeks, the maturation of the central nervous system continues postnatally, which determines its high vulnerability to various pathologic effects. Morphofunctional immaturity and frequent complications of the neonatal period increase the likelihood of early brain lesions leading to further disorders of neuropsychiatric development. Even in the absence of clinically significant neurological abnormalities in the neonatal period, late preterm neonates have a risk of social-adaptive, behavioral, motor and cognitive impairments in later life. Predicting the outcome of central nervous system lesions in late preterm neonates is possible with the help of neuroimaging methods, as well as with the use of specialized tools to assess various areas of psychomotor development. Modern approaches to prevent neurological complications include prevention and treatment of hypoxia, hypoglycemia, hyperbilirubinemia, infections, provision of adequate nutritional support and adherence to vaccination in late preterm neonates.
Generalized arterial calcification of infancy due to mutations of the ENPP1 and ABCC6 genes: phenotype features, bisphosphonate therapy
Authors: Savenkova N. D. , Leviashvili Zh. G. , Barsukova V. N. , Lyubimova O. V.
Published: July 2024

The literature review presents current concepts of the pathogenesis, features of phenotype, course, and prognosis of orphan disease — generalized arterial calcification of infancy, type 1 due to mutation of the ENPP1 gene and type 2 due to mutation in the ABCC6 gene. The published results of clinical observations confirmed the effectiveness of bisphosphonate therapy in pediatric patients with generalized arterial calcification of infancy type 2. The enzyme replacement therapy with recombinant ENPP1, which can prevent arterial calcification and intima proliferation, reduce hypertension and mortality in an experiment on mouse models of ENPP1 deficiency, is promising.
Prader–Willi syndrome with atypical 15q deletion due to an unbalanced translocation between chromosomes 13 and 15
Authors: Shilova N. V. , Minzhenkova M. E. , Markova Zh. G. , Matyschenko G. N.
Published: July 2024

Prader-Willi syndrome (PWS) (OMIM #176270) is a neurobehavioral disorder that is caused by various genetic mechanisms. These mechanisms include a deletion in the q11.2–q13 region of the paternal chromosome 15, maternal uniparental disomy of chromosome 15, or a pathology of gene imprinting in the proximal part of the long arm of chromosome 15. The most common cause of PWS is a 15q11.2–q13 deletion of approximately 6 Mb, which typically occurs spontaneously. However, there have been rare cases of 15q11.2–q13 deletion associated with unbalanced translocations involving chromosome 15. In order to accurately diagnose PWS and determine the mechanisms behind the chromosomal imbalance, various diagnostic methods such as conventional cytogenetics, fluorescence in situ hybridization (FISH) or microarray comparative genomic hybridization are necessary.

The aim. To determine the origin of an atypical 15q deletion in a patient with Prader–Willi syndrome.

Methods. Conventional cytogenetic study, FISH with DNA probes for chromosomes 13 and 15, and chromosomal microarray analysis.

Results. Showed that the patient had an 8.7 Mb deletion in the 15q11.2–q13.3 region, which was found to be a consequence of a meiotic malsegregation of a reciprocal translocation between chromosomes 13 and 15 in the patient’s father. The scope of the results is in informing medical genetic counseling of patients and families with a hereditary disease.

Conclusion. A comprehensive cytogenomic approach in diagnosis of genetic variations associated with Prader–Willi syndrome allows for accurate determination of copy number variations and provides information on the structure and origin of genomic imbalance. This information can be valuable for guiding medical genetic counseling and making decisions regarding future prenatal or preimplantation diagnoses.
Interaction of high-tech perinatal and ophthalmological centers as the basis for favorable outcomes of retinopathy of prematurity
Authors: Tereshchenko A. V. , Trifanenkova I. G. , Vydrina A. A. , Isaev S. V.
Published: July 2024

Purpose. To analyze the incidence, structure and methods of treatment of active retinopathy of prematurity (ROP) in a modern hightech perinatal center by specialists from the federal ophthalmology clinic.

Material and methods. The results of ophthalmological monitoring of 979 premature babies were analyzed. The children’s body weight at birth were 460–2200 g. The gestational age of the children was 22–36 weeks. The children were nursed in the perinatal center “Kaluga Regional Clinical Hospital” from 2021 to 2023. Indications for the treatment were the identification of the 2nd and 3rd stages of active ROP with an unfavorable course, aggressive posterior ROP and ROP of the 1st zone.

Results. For the analyzed period, active ROP was registered in 125 children (12.77%), the aggressive posterior ROP was registered in 4 (0.4%) cases. In the structure of morbidity, ROP with a favorable course accounted for 72% of cases (90 children). The proportion of the 2nd and 3rd stages of ROP with an unfavorable course, subject to treatment was 2.4% and 22.4%, respectively, and aggressive posterior ROP was 3.2%. Treatment of active ROP with an unfavorable course was required in 28% of cases. In 2021, among the used treatment methods, the leading place belonged to laser coagulation of the retina — 72.2%. The technique of intravitreal injections of an angiogenesis inhibitor was used in 2022 in 46.2% of cases, and in 2023 it reached 100%. By 2023, the effectiveness of the treatment with achieving regression of ROP was 100% of cases.

Conclusion. Modern high-tech capabilities for providing care to premature infants in Perinatal Centers, combined with the use of advanced technologies from specialized ophthalmological centers, allow for timely high-tech treatment of active ROP, which ensures that the incidence of severe, disabling forms of the disease is minimized.
Features of the onset of juvenile psoriatic arthritis
Authors: Chebysheva S. N. , Geppe N. A. , Korsunskaya I. M. , Sobolev V. V. , Polyanskaya A. V. , Khachatryan L. G. , Nikolaeva M. N. , Afonina E. Yu.
Published: July 2024

Juvenile psoriatic arthritis is a chronic inflammatory disease of the peripheral joints, spinal joints and entheses, which occurs in 10–25% of patients with psoriasis. Studying the features of the juvenile psoriatic arthritis debut will increase early diagnosis and will help to avoid disability, socialize and integrate the child into society.

Purpose. To identify the relationship between the onset of juvenile psoriatic arthritis and the age and gender of the child, to trace the nature of the articular syndrome in our patients from the onset to the height of the disease.

Methods. 155 patients with an established diagnosis of juvenile psoriatic arthritis were examined. To analyze the data, universal nonparametric (randomization-permutation) algorithms for constructing confidence intervals (CI) and statistical comparisons based on the bootstrap and Monte Carlo methods were used.

Results. It was possible to identify a relationship between the onset variant and the gender of the child. The incidence of asymmetric oligoarthritis in boys and girls at onset was approximately the same, 68% and 59%, respectively, and did not differ significantly. At onset, girls had a higher incidence of rheumatoid-like arthritis (37%) (p<0.005), and boys had a higher incidence of spondyloarthritis (26%) (p<0.005). A relationship was also revealed between the onset, gender and age of the child. Girls aged 0–6 years most often debuted with asymmetric oligoarthritis (90%) (p<0.005), and at the age of 11–15 years — with the rheumatoid-like (polyarticular) variant (73%) (p<0.005). In boys aged 0–6 and 7–10 years, asymmetric oligoarthritis predominated (100% and 100%, respectively) (p <0.005), and at the age of 11–15 years, spondyloarthritis with damage to peripheral joints was more common (73%) (p<0.005). A transformation of the articular syndrome was revealed: if at the onset of the disease asymmetric oligoarthritis was most common (63%), then 5 years from the onset of the disease, 40.7% of the observed children had a rheumatoid-like (polyarticular) variant of the disease.

Conclusion. The course of juvenile psoriatic arthritis may be influenced by the gender and age of the child at onset; a certain pattern of the course of juvenile psoriatic arthritis from oligoarthritis to the polyarticular (rheumatoid-like) variant has been identified.
An Examination of Conflict Resolution Skills and Leadership Characteristics of Gifted Students
Authors: Geçer Songül , Demirel Dingeç Şule , Tamul Ömer Faruk
Published: July 2024

Introduction: Despite the inclusion of leadership skills in the Marland Report, which addresses the characteristics of gifted individuals and their education, there are very few studies, which remained under-researched. Similarly, studies on the conflict resolution skills of gifted individuals, who may show different developmental trajectories in empathy, problem-solving, and conflict resolution compared to their peers, are also scarce. This study, which addresses leadership and conflict resolution skills as part of 21st-century competencies, can provide valuable insights into the status of these skills among gifted individuals.
Method: This study aims to examine the level of conflict resolution skills and leadership characteristics of gifted students and the impact of demographic variables that may affect these two skills. Thus, the relational survey model, a quantitative research method, was employed. The leadership skills and conflict resolution skills of the students were analyzed according to grade level, gender, and the presence of siblings. Additionally, the relationship between the two skills was examined through correlation analysis. Convenient sampling, one of the purposeful sampling methods, was used, and the present study was conducted with 147 gifted middle school students.
Findings: The findings obtained in this study showed that gifted students scored high on both conflict resolution skills and leadership characteristics, and there was a positive and moderate relationship between these two skills. The students’ conflict resolution and leadership skills did not vary by grade level. While leadership skills did not differ by gender, a significant difference was found in favor of female students in the "seeking compromise" sub-dimension of conflict resolution skills (p < .05). When examined according to whether the participants had siblings, no statistically significant difference was found in either leadership skills or conflict resolution and its sub-dimensions.
Discussion: One possible reason for female students scoring higher in the seeking compromise sub-dimension of the conflict resolution scale could be that female students tend to resolve issues more constructively and collaboratively. Male students may tend to solve conflicts with different solutions.
Study of academic dishonesty among students at a tertiary university: Forms, prevalence, and associated factors
Authors:   Laboratory High School, NEUST General Tinio Campus, Nueva Ecija University of Science and Technology, Cabanatuan, Philippines, Cleto Emmanuel Joy T.
Published: July 2024

The purpose of this research was to analyze the prevalence of academic dishonesty among college students at a university and to investigate the different forms it can take and how common these behaviors are. Additionally, the study aimed to identify the factors related to academic dishonesty. The participants were undergraduates studying various subjects at the university. Data was collected through questionnaires and interviews to gather both quantitative and qualitative information about experiences with academic dishonesty. The findings highlighted the common types of academic dishonesty among college students and revealed how often these activities occur. The research also identified potential factors contributing to academic dishonesty, such as peer influence, perceived academic pressure, and a lack of proper instruction in ethical principles. These findings enhance our understanding of academic dishonesty among college students and provide educational institutions and policymakers with valuable insights to develop effective strategies and interventions to address this issue and promote academic integrity.
NVIDIA’s “Chat with RTX” Custom Large Language Model and Personalized AI Chatbot Augments the Value of Electronic Dermatology Reference Material
Authors: Kamel Boulos Maged N , Dellavalle Robert
Published: July 2024

This paper demonstrates a new, promising method using generative artificial intelligence (AI) to augment the educational value of electronic textbooks and research papers (locally stored on user’s machine) and maximize their potential for self-study, in a way that goes beyond the standard electronic search and indexing that is already available in all of these textbooks and files. The presented method runs fully locally on the user’s machine, is generally affordable, and does not require high technical expertise to set up and customize with the user’s own content.
Examining Practices Related to Ethical Aspects in eHealth Evaluation Research: Protocol for a Scoping Review (Preprint)
Authors: Wienands Linda , Valenta Sabine , Leppla Lynn , De Geest Sabina , Kovács László , Teynor Alexandra , Krumme Julia
Published: July 2024

BACKGROUND

eHealth technologies for remote patient monitoring (RPM) hold promise for improving cancer and cardiovascular care. However, they also raise ethical aspects that require careful consideration. Current efforts to address these aspects in primary eHealth research are insufficient. Therefore, a better understanding of how ethical aspects are currently addressed, both in terms of content and methodology, is needed to enhance respective practices.

OBJECTIVE

This scoping review will aim to systematically examine practices in eHealth research concerning ethical aspects. Specifically, it will focus on practices in primary research, evaluating the use of RPM applications in treating cancer and cardiovascular diseases.

METHODS

This review will be conducted in accordance with the JBI methodology and PRISMA ScR guidelines. A comprehensive search strategy will use keywords related to “cancer OR cardiovascular disease” and “eHealth OR remote patient monitoring.” Databases will be searched including MEDLINE, Embase, CINAHL, SocINDEX, Philosophers Index and PsychINFO. Data extraction will follow a mixed deductive-inductive approach, aiming to capture ethical aspects, methodological approaches and potential areas for improvement. Data will be analyzed using basic qualitative content analysis.

RESULTS

The initial search on MEDLINE yielded a total of 10,407 results. The final results of this research are expected to be presented in winter 2024/2025.

CONCLUSIONS

The results of this scoping review will inform recommendations for improving practices regarding the consideration of ethical aspects in primary eHealth evaluation research.

CLINICALTRIAL

This protocol is registered on the Open Science Framework website (registration link: https://osf.io/7xafv/).
Influence of Partnership Relationships on Long-Term Neurological Rehabilitation in Germany: Protocol for a Qualitative Retrospective Study (Preprint)
Authors: von Bosse Alexa , König Peter , Jansen Eva
Published: July 2024

BACKGROUND

Acquired neurological diseases entail significant changes and influence the relationship between a patient and their significant other. In the context of long-term rehabilitation, those affected collaborate with health care professionals who are expected to have a positive impact on the lives of the affected individuals.

OBJECTIVE

This study aims to examine the changes in the relationship between the patient and their loved ones due to acquired neurological disorders and the influence of health care professionals on this relationship.

METHODS

Through sociogenetic type building, we will identify different types of patient-caregiver dyads and their effects on health care professionals and vice versa. The results will then be integrated into a model based on the theory of symbolic interactionism and Baxter’s Relational Dialectics Theory.

RESULTS

This study is not funded and was approved by the ethics committee of the German Society for Nursing Science, and it complies with the Declaration of Helsinki. The data collection started in June 2024 based on narrative couple interviews and is running. We assume that patients and their relatives will demonstrate heterogeneity as individuals, as well as in their interactions within the dyad, regarding certain orientations such as coping with illness, motivation for therapy, and coping strategies.

CONCLUSIONS

Our findings address a biopsychosocial perspective that enhances treatment approaches in neurological long-term care. Understanding the influence of professionals on dyadic couple relationships can improve rehabilitation effectiveness by tailoring therapeutic approaches to various patient types, relatives, and dyadic relationship constellations. This fosters patient- and family-centered therapy in line with holistic care.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/63949
A 3-Month Comparison of Blueberry and Date Consumption among Older Adults: Rationale, Protocol, and Initial Recruitment for a Randomized Controlled Trial (Preprint)
Authors: Mukamal Kenneth J. , Seager Reva , Kramer Daniel B. , Arnaout Ramy , Davis Roger B. , Sahni Shivani
Published: July 2024

BACKGROUND

Although anthocyanin-rich foods have been associated with health benefits, it is unclear how well these effects extend to older adults and common geriatric syndromes. In addition, many studies have relied upon supplements or food extracts, and the effects of whole-food supplementation remain uncertain.

OBJECTIVE

To determine the effectiveness of highbush blueberry supplementation, compared with an isocaloric serving of Deglet Noor dates, on blood pressure, physical function, falls, cognition, and other domains relevant to older adults.

METHODS

We are conducting a single-center randomized controlled trial among older adults residing in the greater Boston, MA region. Eligible participants include women and men aged 70 years and older. The trial was planned for conduct at a single congregate living facility for older adults, but after the COVID-19 pandemic hit, the initial recruitment was moved to an alternate senior congregate living facility and has subsequently been expanded to a second facility and the larger community. Participants are randomized on a 1:1 basis to consume 1 cup of frozen blueberries or 2-3 pitted dates daily for 3 months. Following a one-week wash-out, participants attend a fasting baseline visit that includes phlebotomy, questionnaires, functional assessments, anthropometric measurements and 24-hour electrocardiographic monitoring and ambulatory blood pressure monitoring. Participants return after 3 months for identical measurements. Recruitment was planned for 70 individuals with 15% attrition.

RESULTS

Recruitment for the trial began in April 2022 and ended in April 2024, when the originally planned number of completers was reached. The final population included 61 participants with a median age of 76 years (range 70-94 years), 56% women, and 53% assigned to blueberries. The demographic characteristics of enrolled participants demonstrate the tradeoffs of recruitment based in senior congregate living facilities, with unusually advanced ages but limited racial diversity and a fixed pool of potential participants.

CONCLUSIONS

This randomized trial will test the effectiveness of whole highbush blueberry supplementation, compared with an isocaloric serving of dates, upon physiological and clinical parameters of interest to older adults. With its emphasis on whole foods, its results will add to a growing number of studies that test the effects of anthocyanins on common chronic diseases of aging.

CLINICALTRIAL

The trial is registered at clinicaltrials.gov (NCT05358210).
The Role of Relevance in Shaping Perceptions of Sleep Hygiene Games Among University Students: Mixed Methods Study (Preprint)
Authors: Liang Zilu , Melcer Edward , Khotchasing Kingkarn , Chen Samantha , Hwang Daeun , Hoang Nhung Huyen
Published: July 2024

BACKGROUND

Sleep games are an emerging topic in the realm of serious health game research. However, designing features that are both enjoyable and effective at engaging users, particularly university students, to develop healthy sleep habits remains a challenge.

OBJECTIVE

This study aims to investigate user preferences for 3 sleep game prototypes, that is, Hero’s Sleep Journey, Sleep Tamagotchi, and Sleepland, and to explore their popularity and perceived utility in promoting sleep health.

METHODS

A mixed methods approach was used in this study. Quantitative and qualitative data were collected through a co-design workshop involving 47 university students. Participants were presented with storyboard cards of game features and were asked to provide an overall rating on each game, as well as ratings for individual features. They were also encouraged to provide free-form comments on the features and suggest improvements. In addition, participants were asked to express their preferences among the 3 games regarding which game they would most like to play and which one they found most useful for promoting sleep health.

RESULTS

Surprisingly, while Hero’s Sleep Journey was the most popular choice among participants, Sleep Tamagotchi was perceived as the most beneficial for improving sleep health. Relevance emerged as an overarching theme in the qualitative data analysis, with 3 interconnected dimensions: psychological relevance to users’ personal lives, logical relevance to sleep health, and situational relevance to users’ circumstantial context. We discussed how the 3 dimensions of relevance address the autonomy and relatedness constructs outlined in the self-determination theory and proposed 3 design recommendations.

CONCLUSIONS

Our serious sleep game prototypes demonstrated the potential to engage university students to develop healthy sleep hygiene. Future sleep game designs should aim to create a sense of relevance to users’ personal lives, sleep health goals, and situational contexts. Rather than a one-size-fits-all approach, it is essential to develop a wide range of game genres and features to cater to diverse users. Aligning game features with sleep health goals and educating users on the design rationale through sleep knowledge are also important aspects. Furthermore, allowing users to customize their game experience and manage technology boundaries is necessary to nurture a sense of control and autonomy in the process of forming good sleep hygiene.
Comparative Evaluation of Efficacy of Honey Thermal micro cautery (Kshoudra Agnikarma) versus Standard Physiotherapy versus Sida cordifolia oil via nasal administration (Nasya Karma) in the management of Frozen Shoulder (Avabahuka) (Preprint)
Authors: Pathania Shalini , Parwe Shweta , Sawarkar Punam , Nisargandha Milind
Published: July 2024

BACKGROUND

Frozen shoulder(Avabahuka) is a shoulder ailment that denotes dysfunction in the arm. Sage Sushrut has considered Frozen shoulder(Avabahuka) and bodily humor disease (Vata Vyadhi). Frozen shoulder hampers a person’s day to day activities. With a frozen shoulder, the range of motion of the shoulder joint is limited. Administering oil through the nasal route (Nasya karma) is mentioned in Ayurvedic Scriptures for managing disorders of the above head and neck (Urdhwajatrugata rogas). Thermal microcautery (Agnika arma) is a parasurgical procedure for treating related pathologies of bodily humor (Vata and Kapha). In the modern world, physiotherapy and exercise are the chosen lines of treatment. With this context in mind, our study will aim to compare the efficacy of Honey Thermal micro cautery (Kshoudra Agni karma) versus Standard Physiotherapy versus cordifolia oil via nasal administration in the treatment of frozen shoulder to find out the best among these three in terms of providing relief from the complaints.

OBJECTIVE

Primary objectives of this study are firstly to evaluate the efficacy of Honey thermal micro cautery (Kshoudra Agnikarma) on VAS, R.O.M., S.P.A.D.I secondly to evaluate the efficacy of Standard Physiotherapy on VAS, R.O.M., S.P.A.D.I. thirdly evaluate the efficacy of Sida cordifolia oil via nasal administration (Shudhabala Taila Nasya) on VAS, R.O.M., S.P.A.D.I. and lastly To compare the efficacy of Honey thermal micro cautery (Kshoudra Agnikarma), Standard Physiotherapy, Sida cordifolia oil via nasal administration (Shudhabala Taila Nasya) on VAS, R.O.M., S.P.A.D.I. The secondary objective is to study the sustained relief individually in all three groups.

METHODS

For this study, we will enrol 60 patients. Group A will receive Thermal micro cautery using honey for two days (1st and 7th ) and placebo capsules for seven days, and Group B will receive Standard Physiotherapy and placebo capsules for seven days; Group C will be given Sida cordifolia oil via nasal administration with eight drops in each nostril and placebo capsules for seven days.

RESULTS

The result will be subjected to statistical analysis using appropriate methods.

CONCLUSIONS

Kshoudra Agnikarma, Standard Physiotherapy may be more efficacious than Shudhabala oil nasal administration in managing Frozen shoulder (Avabahuka) with more sustainability.

CLINICALTRIAL

CTRI/2023/11/059594 ( clinical trial registry India)
Звернення головного редактора
Authors: Authors No
Published: July 2024

No abstract
ROLE OF DUAL-ENERGY COMPUTED TOMOGRAPHY IN THE EMERGENCY DIAGNOSIS OF KNEE BONE MARROW EDEMA: A COMPARATIVE STUDY WITH MAGNETIC RESONANCE IMAGING
Authors: GEETHANJALI SUNDARAM  , SEETHARAMAN CANNANE  , TAPAS KUMAR SAHU  , JEEVITHAN SHANMUGAM  , PANKAJ MEHTA
Published: July 2024

Objective: Key markers of injury processes in acute knee trauma are bone bruises, which are detected by magnetic resonance imaging (MRI) as increased signal intensity on T2-weighted images and signal loss on T1-weighted imaging. However, due to its restricted availability and lengthy acquisition times, particularly in emergency situations, MRI is not often employed in knee trauma cases. A viable substitute is dual-energy computed tomography (DECT) with virtual non-calcium (VNCa) techniques, which improves bone marrow edema (BME) visibility and allows for greater material distinction. This study uses MRI as the reference standard to assess the diagnostic performance of third-generation DECT and VNCa methods for detecting BME in acute knee injuries.
 Methods: This prospective observational study involved 40 patients with acute knee trauma who had both MRI and DECT between July 2019 and July 2021 at Kovai Medical Center and Hospital in Coimbatore. Individuals who were pregnant had a history of knee injuries or were above the age of 18 were eliminated, as were those who had an MRI or CT contraindication. Siemens Healthcare’s Somatom Force, a third-generation 192-slice dual-source CT scanner, was used for DECT imaging, while Philips Ingenia 1.5T was used for MRI. Image analysis used SPSS version 27.0 for statistical analysis to determine whether BME was present in MRI and DECT images.
Results: The study participants had a mean age of 47±16 years, predominantly male (72.5%). DECT demonstrated a sensitivity of 81.15% and a specificity of 96.70% for detecting BME compared to MRI. The diagnostic accuracy was notably high in the lateral femoral condyle (sensitivity and specificity of 93.33%) and the lateral tibial condyle (sensitivity and specificity of 86.36%). Overall, DECT identified 59 out of 69 MRI-positive regions, reflecting its robustness in detecting true positives and true negatives in acute trauma settings.
Conclusion: Third-generation DECT with VNCa techniques is a highly effective imaging modality for detecting edema of the bone marrow in acute knee trauma, offering high diagnostic accuracy comparable to MRI. It is ability to provide clear visual differentiation and rapid acquisition makes it a valuable alternative, particularly in emergency settings where MRI is unavailable or contraindicated. DECT’s shorter reconstruction time and high reliability can optimize workflow and improve patient outcomes, underscoring its potential role in early diagnosis and management of knee trauma.
Building information modeling for Public Private Partnership Projects A literature review and future research directions
Authors: Al-Shamayleh Ali , Zakaria Sharifah , Rahim Nur , Totanji Doa’a Al
Published: July 2024

The main focus of the Public Private Partnership (PPP) is to maximise the projects' profitability. Building Information Modeling (BIM) can help decision-makers make educated decisions throughout the project's life cycle. However, despite the number of studies on BIM for PPP projects, many challenges, inconveniencies, and hurdles still face the successful and feasible implementation of BIM in PPP projects. The study presents a systematic review based on an in-depth review of 56 journal articles published from 2012 to 2022 of the status of Building Information Modeling (BIM) adoption in Public Private Partnerships (PPP) projects, highlights current trends and patterns, and systematically outlines future research agenda. Finally, it is hoped that this research will argue for the future development of a smoother BIM adoption in PPP projects to overcome hurdles and improve overall project outcomes. The results of this study clarify the current research areas and future research agenda in the field of BIM for PPP projects. Defining current and future research on the topic will help the smooth implementation of BIM in PPP projects to reap the benefits, overcome the challenges and provide key decision-makers with the ability to make educated decisions across the project life cycle.
Transcending Boundaries: Wole Soyinka’s Fusion of African and Western Dramatic Traditions in A Dance of the Forests
Authors: Panda Asit
Published: July 2024

The objective of this research article is to investigate the innovative fusion of Western and indigenous performance traditions that Wole Soyinka employs in his celebrated tragedy, A Dance of the Forests. This study identifies specific indigenous and European forms and performance idioms that contribute to Soyinka's tragedy through an in-depth analysis of the play's structure, themes, and performance techniques. This article emphasises Soyinka's incorporation of Western theatrical devices and traditions, as well as Yoruba mythology and traditional performance elements such as percussion, dance, music, and song. The reclamation and affirmation of precolonial indigenous theatrical forms and performance idioms make a substantial contribution to the assertion of indigenous identity. Soyinka's use of dramaturgy in A Dance of the Forests exemplifies the theatre's capacity to transcend artistic and cultural limitations. This article positions Soyinka's dramatic work as a response to the asserted dominance of Western modernity, reflecting a post-colonial society's endeavour to establish a legacy of alternative modernity in the artistic sphere.
Decolonizing Performance: Wole Soyinka’s Synthesis of Theatrical Traditions in Death and the King’s Horseman
Authors: Panda Asit
Published: July 2024

This research article seeks to focus on exploring the diverse facets of Wole Soyinka's blending of indigenous and Western performance traditions in his groundbreaking tragedy, Death and the King's Horseman. This research article, through the examination of Soyinka's inventive dramaturgy in Death and the King's Horseman, explores how the playwright challenges the established norms of the stage by subverting the dominance of western theatrical conventions. The article underscores the dexterous integration of Yoruba cultural elements with Western dramatic techniques that Soyinka employs in his performances, resulting in a theatrical experience that transcends cultural boundaries. This study further explores how this fusion functions as a form of resistance against the cultural domination of Europe. This article posits that Soyinka’s creative combination of African and Western theatrical traditions in Death and the King’s Horseman serves the greater purpose of decolonizing the stage. Soyinka’s incorporation of indigenous performance idioms contributes to the growth of the nationalist cultural renaissance, revitalizing indigenous artistic tradition.
Oratory as Political Theatre: Performative Dynamics in Bangabandhu Sheikh Mujibur Rahman's March 7, 1971 Speech
Authors: Sikder Sumon , Rahmatullah Mohammad , Uddin Mohammad Jashim
Published: July 2024

This paper examines the performative dimensions of Bangabandhu Sheikh Mujibur Rahman's seminal March 7, 1971, speech through the lenses of Erving Goffman’s dramaturgical analysis and Richard Schechner’s performance theory. By deconstructing the speech’s gestural rhetoric, vocal dynamics, and audience engagement, this study elucidates how Bangabandhu's oratory transcended mere political discourse to become a potent act of political theatre. The analysis reveals that through strategic use of gestures, pauses, and direct interaction with the audience, Bangabandhu not only conveyed his message with compelling clarity but also fostered a robust communal identity and mobilized collective action. The symbolic and ritualistic elements embedded within the speech further underscore its transformative impact on the Bengali liberation movement. This scholarly exploration offers valuable insights into the intersection of performance and politics, highlighting the enduring relevance of performative strategies in contemporary political oratory. The practical implications of this study extend to enhancing the efficacy of political communication and leadership in mobilizing societal change.
Лазерное термоупрочнение и восстановление штампов (в том числе крупногабаритных) с использованием мобильного лазер-­робота
Authors: Чухланцев Д.О. , Умнов В.П. , Силантьева Д.А. , Шишкин Е.С.
Published: July 2024

В статье представлен мобильный лазер-­робота МЭЛ‑3.0 для лазерного термоупрочнения и наплавки широкого перечня изделий, снабженный диодным лазером. Робот создан компанией ООО «ТермоЛазер». Приведены примеры термоупрочнения матриц штампов и их восстановления на некоторых предприятиях. Обсуждаются возможности мобильного роботизированного лазерного инструмента и некоторые вопросы его использования применительно к крупногабаритным объектам, в том числе непосредственно на месте их эксплуатации.
Повышение ресурса работы инструментальных сталей при лазерной закалке
Authors: Бирюков В.П. , Горюнов Я.А.
Published: July 2024

В работе рассмотрены результаты металлографических и триботехнических испытаний инструментальной стали Х12 в паре трения с объемно закаленной сталью 40Х при смазке индустриальным маслом И20. Показано, что применение поперечных колебаний лазерного луча значительно повышает производительность обработки. Установлено, что качественное лазерное термическое упрочнение кромок образцов возможно только с применением поперечных колебаний луча при воздействии непрерывным лазерным излучением. При оптимальных режимах лазерной обработки и упрочнении 50% поверхности трения образцов износостойкость повышалась в 1,6 раза по сравнению с объемной закалкой.
Отечественный рынок фотоники
Authors: Истомина Н.Л. , Карякина Л.В.
Published: July 2024

Чуть более месяца прошло с момента закрытия выставки «Фотоника. Мир
лазеров и оптики‑2024», в рамках которой сопровождающая экспозицию Деловая
программа вызвала такой же большой интерес. «Лицом к лицу лица не увидать: большое видится на расстоянье…». Теперь можно окинуть взглядом отечественный
рынок фотоники, сделать какие-то выводы, пусть пока и поверхностные, о состоянии
оптико-электронной отрасли, лазерного станкостроения, производства лазерной техники, приоткрыть завесу над продукцией фотонной отрасли Китая.
Влияние температуры подложки на оптические свой­ства тонких пленок GaSe, полученных методом PECVD
Authors: Кудряшов М.А. , Мочалов Л.А. , Кудряшова Ю.П. , Слаповская Е.А. , Вшивцев М.А. , Крюков Р.Н.
Published: July 2024

Впервые тонкие пленки GaSe были получены методом плазмохимического осаждения
из газовой фазы (PECVD), где в качестве исходных веществ использовались высокочистые элементарные галлий и селен. Инициирование взаимодействия элементов осуществлялось ВЧ-разрядом (40,68 МГц) при пониженном давлении 0,1 Торр. Исследованы состав, морфология поверхности, структурные и оптические свойства пленок селенида галлия в зависимости от температуры подложки. Осажденные пленки поликристаллического GaSe были получены на сапфировой подложке при температурах 250 и 350 °C, а аморфные пленки GaSe – при 150 °C.
A Preliminary Survey of Airborne Fungal Spores of Vittaleshwar Temples at Sironcha (M.S.)
Authors: Shende Sandip H.
Published: July 2024

Abstract: Fungal spores constitute the major portion of bio pollutant. Temple is religious place where people from various places gather to get their wishes fulfil. So it was decided to study the indoor aeromycoflora of few temples of Sironcha. Rotorod sampler was used for collection of airborne fungal spores .Sampler was run daily between 10:00 a.m. to 11:00 a.m. from June to December (2022). During investigation period total 12 types of fungal spores recorded viz. Aspergillus, Alternaria, Bispora, Cercospora, Chaetomium, Cladosporium, Fusarium, Curvularia, Helminthosporium, Nigrospospora, Penicilium and Torula. Among these Cladosporium and Aspergillus, were dominant. Dark, damp and moisture condition, presence of biogenic material and droppings of many birds help the fungus grow. These fungi are allergenic to the human beings. Therefore, the area of temple should be cleaned regularly. This information will be significant to allergy patients.
Antimicrobial Activity of Biosynthesized Copper Nanoparticles Using Methanolic Extract of Ocimum Sanctum
Authors: Biswas Rishav
Published: July 2024

Abstract: Methanolic extract of Ocimum sanctum leaves were used as a reducing and stabilizing agent for the synthesis of copper nanoparticles (CuNPs). It is a cost-effective and eco-friendly process. On the treatment of Ocimum sanctum leaf extract with copper sulphate solution, stable CuNPs were formed. The formed CuNPs were characterized under UV-Vis spectrophotometer. The biologically synthesized copper nanoparticles show high antibacterial activity against opportunistic pathogen Staphylococcus aureus. The antimicrobial activity was determined by three assays with agar well diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) and the values were compared to observe the antimicrobial efficacy of the CuNPs.
Pengaruh Persepsi dan Manfaat Digitalisasi terhadap Keputusan Pembayaran Infaq
Authors: Febriyanti Laela Dwi , Rusdianto Rusdianto
Published: July 2024

The digital transformation of infaq management in Indonesia marks a strategic shift towards increased transactional efficiency and transparency. With technological advancements, the use of digital platforms for religious donations has grown, altering the landscape of charitable giving. This study aims to explore the impact of perceived ease of use, security, transparency, trust, and perceived benefits on donor decision-making in online infaq payments. Employing a quantitative approach, data were collected from 100 respondents in the Special Region of Yogyakarta (DIY), selected based on their experience with online infaq payments, residency, employment status, and religious adherence. Multiple regression analysis conducted using SPSS revealed that ease of use, trust, and perceived benefits significantly influence donor decisions, whereas security and transparency do not. These findings highlight the importance of ease and benefits in enhancing the adoption of online infaq payments.
Abstrak
Transformasi digital dalam pengelolaan infaq di Indonesia menandai pergeseran strategis menuju peningkatan efisiensi dan transparansi transaksi. Seiring dengan perkembangan teknologi, penggunaan platform digital untuk donasi keagamaan meningkat, mengubah lanskap pemberian amal. Penelitian ini bertujuan untuk mengeksplorasi pengaruh persepsi kemudahan penggunaan, keamanan, transparansi, kepercayaan, dan manfaat yang dirasakan terhadap keputusan donatur dalam pembayaran infaq online. Menggunakan pendekatan kuantitatif, data dikumpulkan dari 100 responden di Daerah Istimewa Yogyakarta (DIY), yang dipilih berdasarkan pengalaman pembayaran infaq online, domisili, status pekerjaan, dan kepatuhan beragama. Analisis regresi berganda dengan SPSS mengungkap bahwa kemudahan penggunaan, kepercayaan, dan manfaat yang dirasakan berpengaruh signifikan terhadap keputusan donatur, sedangkan keamanan dan transparansi tidak. Temuan ini menekankan pentingnya faktor kemudahan dan manfaat dalam meningkatkan adopsi pembayaran infaq online.
Análisis de la dinámica del aprovechamiento del agua y del nitrógeno con mezclas de zeolita durante el crecimiento vegetativo del maíz (Zea mays) en un suelo Andisol de la zona de Poás de Alajuela
Authors: Blanco Espinoza Raul Andres , Brenes Paola , Peña Wagner
Published: July 2024

Con una creciente población mundial y una reducción significativa en las tierras de cultivo, es de suma importancia la eficientización de la agricultura, ya sea en el aprovechamiento del agua y en el uso correcto de los fertilizantes químicos, en especial las fuentes nitrogenadas. Por este motivo, es que se evaluó la zeolita como un mejorador en el aprovechamiento del agua, por medio de la reducción de la evapotranspiración y como eficientizador de los fertilizantes nitrogenados, reduciendo de esta forma su uso. El ensayo experimental requirió de un cultivo indicativo (maíz), basado en cinco tratamientos (TA: 100% Fertilizante, TB: 25%Z+75% ½ fertilizante, TC: 25%Z+75% fertilizante, TD: 25%Z+75% doble fertilizante, TE: 100%Z+100%fertilizante), con 15 repeticiones, para poder evaluar el consumo de agua y pesos frescos y secos, además de análisis químico de suelo, para medir el remanente de N y análisis químico foliar, para observar el consumo de nutrimento, también se evaluó la relación C/N, para evidenciar la influencia del mineral en la microbiota del suelo. Los resultados, demuestran que a pesar de que en los primeros 21 dds existe diferencia estadística entre los tratamientos, para las demás mediciones (42 y 70 dds) ocurre todo lo opuesto, aspecto muy similar se presenta en el desarrollo de biomasa, donde no se evidencia diferencia estadística. En cuanto a presencia de N remanente, los tratamientos con el porcentaje más altos son el A y E, presentando estos a la vez una mayor cantidad de N foliar, mientras que en lo que a la relación C/N, la más elevada la presentó el tratamiento B (>10) que, a la vez, posee la menor cantidad de fertilizante