bluuebunny/crossref_metadata_2025 huggingface dataset:
The problem of finding eigenvalues and eigenfunctions of boundary value problems for an equation of mixed type
Authors: Tojiboev Ibrokhimjon Tojaliyevich
Published: February 2025

In this work, we investigate the eigenvalue problem for an elliptic-hyperbolic equation with a non-smooth line of type changing within a special domain. The boundary conditions considered include Frankl’s condition, which is crucial for such problems involving mixed type equations. We derive the eigenvalues and corresponding eigenfunctions of the problem, paying special attention to the structural complexities introduced by the discontinuity in the equation’s type across the domain. Furthermore, we rigorously prove that the system of eigenfunctions obtained from the problem is not complete in the L
2 space, meaning that not every square-integrable function in the domain can be represented as a series expansion in terms of these eigenfunctions. This non-completeness is demonstrated by constructing a specific function orthogonal to the entire system of eigenfunctions. We utilize advanced techniques, including the transformation to polar coordinates and variable substitution, to express integrals involving Bessel functions, thereby providing a clear framework for proving the non-completeness. Our findings are applicable to both symmetric and anti-symmetric cases of the problem, with boundary conditions that either involve equal or opposite values at points reflected across a line of symmetry. This study highlights significant challenges in dealing with mixed-type equations and contributes to the broader understanding of how eigenvalue problems with Frankl’s conditions behave in non-standard geometries, particularly in domains with discontinuities.
Topogenous orders on forms
Authors: Iragi Minani , Holgate David , Šlapal Josef
Published: February 2025

Departing from a categorical concept of topogenous orders defined relative to the bifibration of subobjects, we introduce and discuss topogenous orders on forms, i.e., faithful and amnestic functors. These topogenous orders are shown to include both closure and interior operators on forms. We define and study two special morphisms relative to a topogenous order, namely strict and final morphisms. We give a characterization of the two morphisms by the help of their cartesian and cocartesian liftings. Some examples from topology and algebra demonstrating our results are included.
Monastic Estates in the Wachau Region: Nodes of Exchange in Past and Present Days
Authors: Gruber Elisabeth , Kühtreiber Thomas
Published: February 2025

In the Lower Austrian part of the Danube region, known as the Wachau, viticulture as an agrarian form of economy was established to a large extent by monastic estates. From the ninth century onwards at the latest, numerous monasteries in Austria, Salzburg, Bavaria, and Bohemia came into possession of vineyards in the Wachau by donation or purchase. Charters, urbaria, and tax lists document the importance of these mostly far-off properties from the beginning of the thirteenth century. Viticulture played a special role in this process. This is even more remarkable because the distances between the monastery and the estates – the so-called “Lesehöfe” – were sometimes considerable, for example, in the case of the Augustinian canons’ monasteries of Herrenchiemsee (Traunstein, Bavaria) and Höglwörth (Berchtesgaden, Bavaria) or the Benedictine monasteries of Prüfening (Regensburg, Bavaria) and Tegernsee (Miesbach, Bavaria) and the Hochstift Freising. These far-off estates served as an interface for the interests of both local and foreign actors, still visible today in the form of surviving buildings and historical documents and objects. As part of a project, the monastery estates and their historical documents were catalogued to establish a basis for an interdisciplinary analysis of the phenomenon. The essential goal of the project was to record the monastic estates as broadly as possible to create a basis for an interdisciplinary analysis of the phenomenon. Basic groundwork was laid to make the various estates available for the interests of cultural tourism within the Wachau World Heritage region.
Sabbatical Framework of Sacred Times in H
Authors: Young Hye Kim
Published: February 2025

This essay explores the significance of the Sabbath’s inclusion in Leviticus 23 by analyzing the expressions שבת שבתון, שבתון, and שבע שבת[ו]ת. It uncovers a framework linking the Sabbath, Day of Atonement, and Sabbatical Year, highlighting the Sabbath’s central role. This study investigates the seventh-month festivals and examines the social justice implications of the Sabbatical Year, Jubilee, and grain harvest festival, all structured around the Sabbath concept. The findings indicate that H’s sabbatical framework marks a significant development in the conceptualization of sacred time.
Educación y sociedad: hacia un nuevo giro epistemológico decolonial
Authors: Cruz Picón Pablo Emilio
Published: February 2025

The objective of this essay is to redefine the value of the approaches of Latin American theorists, such as Boaventura, Dussel, Freire, Grosfoguel, Zea and Zuleta, among other authors, who advocate a decolonial education based on criticality, cultural diversity, own knowledge, emancipation, and liberation, among other features. For this reason, the analysis was based on a qualitative hermeneutic-analytical approach. Among the main contributions, it is determined that the construction of a decolonial pedagogy is obtained from a polynomial epistemic-humanist-ethical alliance: the recognition of the other, interculturality, critical-emancipatory pedagogy, and the validity of ancestral knowledge. It is concluded that the decolonial turn and epistemological decolonization not only outlines theoretical perspectives, but also a possible cognitive pragmatism that guides epistemic praxis to a sociopolitical terrain, where human beings recognize their history and place in the world.
Association between proton pump inhibitors and anti-coagulants for a better prevention of gastrointestinal bleeding
Authors: Alotaibi Fahad Mudhi , Alotaibi Nasser Faihan , Alsubaie Faisal Farraj , Ekhuraidah Hussain Ali , Koshan Mohammed Ahmed , Alzahrani Rayan Hassan , Alghamdi Hamdan Saleh , Allehibi Abed Houmod , Aljumah Abdulrahman Abdullah
Published: February 2025

Background and aim. Gastrointestinal bleeding (GIB) is one of the most common medical emergencies. Proton pump inhibitors (PPI) are among the most widely used drugs in gastroenterology to treat various types of acid-related disorders. We aim to investigate the safety of proton pump inhibitors (PPIs) when used concurrently with anticoagulants in patients with upper and lower gastrointestinal bleeding (GIB) and assess the risk of hospitalization, GIB, and mortality in patients receiving this combined treatment.
Methods. A retrospective multicenter study was conducted at two tertiary care hospitals. Patients were selected according to inclusion and exclusion criteria. Demographic data, vital signs, medical history, physical examinations, comorbid conditions, medications, laboratory investigations, endoscopy findings, management, and complications were retrieved from the medical records of all participants.
Data obtained from all patients’ medical records were reviewed. Endoscopic findings and management of the bleeding site were collected according to the presenting symptoms. Statistical analyses were performed using IBM SPSS version 25.0 software.
Results. Our results revealed a significant increase in acute GIB risk with the number of concurrent anticoagulants used, particularly in patients not using PPIs. Those using four anticoagulants along with PPIs had a lower likelihood of acute GIB at 6.3% (P = 0.0001). Patients taking two or three anticoagulants also experienced reduced GIB risk when PPIs were added (P ≤ 0.05). Age played a role, with a statistically significant difference between PPI users and non-users, especially in the 31-40 age group, where PPI users had a higher incidence of GIB (69.80%) compared to non-users (30.20%) (P < 0.05). Comparing patients on anticoagulants with or without PPIs, the study found a lower risk of hospitalization (adjusted hazard ratio, AHR: 1.02; 95% CI: 0.92-1.57) and mortality (AHR: 1.00; 95% CI: 0.84-1.11) in those using Rivaroxaban and PPIs concurrently. By contrast, patients using Rivaroxaban alone without PPIs faced an increased risk of hospitalization (AHR: 1.15; 95% CI: 0.98-2.35) and mortality (AHR: 1.12; 95% CI: 0.90-1.37).
Conclusions. Combining PPIs with anticoagulant drugs reduced the risk of GIB, hospitalization, and mortality, particularly in older adults, thereby mitigating potential complications.
Comparative Assessments of PET and ASL MR Perfusion in the Evaluation of Early Dementia
Authors: Jain Savyasachi , Gaikwad Shailesh B , Charan Bheru Dan , Gupta Anu , Tripathy Madhvi
Published: February 2025

Background: Overtly morbid dementing diseases have a prodromal MCI (mild cognitive impairment) phase which is crucial to recognize. Clinical scores provide an easy bedside assessment tool for holistic cognitive evaluation but fail to provide lead time. While routine biomarkers of brain atrophy are late to appear, non-contrast MRI perfusion studies like ASL may serve as a valuable alternative to 18F-FDG-PET for the recognition and classification of the degree of neurodegeneration in individuals with MCI, especially when FDG-PET is not available. Our study adds confidence as we noted brain regions where PET-ASL concordance was most robust and devised concordance with ACE-3 scores.Material and methods: We conducted a prospective study from Jan 2021 to Jan 2024. Cases were selected based on the inclusion and exclusion criteria, which have objective cognitive impairment. Healthy controls were selected. MRI and PET scans were performed in all cases. Perfusion values of arterial spine labeling, PET, and clinical examination were recorded.Results: We included 33 patients and 15 healthy controls in the study. We compared ASL and PET for all selected individuals. Our study showed that ASL can detect a hypo-perfusion region with a 91% sensitivity, 85.98% specificity, 89.8% PPV, and 87.62% NPV, with a diagnostic accuracy of 88.9%.Conclusion: ASL was a dependable replacement for the gold-standard FDG-PET. ASL may serve as a valuable alternative to 18F-FDG-PET for classifying the degree of neurodegeneration in individuals with prodromal AD, especially when FDG-PET is unavailable.
Uwagi katechetyczne – nieznany tekst ks. Walentego Gadowskiego przeznaczony dla rodziców „by umieli pomagać w nauczaniu”
Authors: Jaworski Piotr
Published: February 2025

Ks. Walenty Gadowski należał do jednego z pionierów ruchu odnowy katechetycznej, propagatorem nowych metod szeroko rozumianej edukacji religijnej. Ksiądz W. Gadowski opracował katechizmy z nowym sposobem prze­kazu wiedzy. Wprowadził ilustracje, teksty Pisma Świętego, opowiadania biblijne, przykłady z dziejów ojczystych i życia świętych. Katechizmy prze­mawiały więc do całej osobowości ucznia.
Wkład ks. W. Gadowskiego we współczesną katechetykę jest ogrom­ny. Był on przede wszystkim praktykiem katechezy, odważnym pionierem, który nie bał się szukać nowych dróg, rozwiązań w nauczaniu religii, nie rezygnując z dorobku naukowego i doświadczenia jego poprzedników oraz katechetyków, a co najważniejsze, sam był nie tylko autorem katechizmów dla dzieci, młodzieży, dorosłych, ale również znakomitym praktykiem kła­dącym duży nacisk na dostosowanie nauczania do możliwości percepcyj­nych odbiorców, czyli na przystępność nauczania.
Archiwum Diecezjalne w Tarnowie posiada w swoich zasobach bogatą spuściznę naukową ks. Walentego Gadowskiego, a wśród nich również teksty praktycznie nieznane, gdyż nie były nigdzie publikowane, lub publikowane tylko częściowo.
W poczet tych pism należy zaliczyć: Wychowanie religijne, Dydaktykę i metodykę, Pedagogikę chrześcijańską oraz tzw. Czytanki majowe[1] pisane z myślą o nabożeństwach majowych w diecezji ale i poza jej terenem. Oprócz wymienionych do tego zbioru zaliczyć należy także mniej obszerne teksty jak: Przygotowanie do pierwszej spowiedzi i pierwszej Komunii św. dla dzieci w wieku przedszkolnym, Katechizowanie elementarne, czy też niezwykle ważny tekst W sprawie ulepszenia katechizmu. W zbiorach stanowiących spuściznę ks. Gadowskiego znajduje się również liczący 7 kart niezwykle ciekawy tekst Uwagi katechetyczne napisany w Bochni w 1951 r. i dotyczący wskazówek dla rodziców odnośnie edukacji i wychowania religijnego. Wszystkie wspomniane teksty pozostają w zbiorach tarnowskiego Archiwum Diecezjalnego.
 
[1] Należy w tym miejscu podkreślić, że wspomniane pisma tj. Wychowanie religijne, Dydaktykę i metodykę, Pedagogikę chrześcijańską oraz tzw. Czytanki majowe są w chwili obecnej na etapie opracowania edycji źródłowej w ramach badań prowadzonych przez Ks. Jacka Siewiorę i autora prezentowanego artykułu.
It takes four to tango: the cooperative adventure of scientific publishing
Authors: Carmona-Gutierrez Didac , Kainz Katharina , Madeo Frank
Published: February 2025

The publication and scientific implementation of scholarly articles is a collaborative effort that unites readers, authors, editors, and referees. A scientific journal thereby serves as a vital platform, enabling these interactions and fostering a shared commitment to advancing the quality and impact of scientific communication. In this short editorial, we celebrate the milestone of publishing the 500th article in Microbial Cell by highlighting these collective efforts. Importantly, from the outset of the journal more than ten years ago, we have cultivated a handcrafted organ that is produced by scientists for scientists. In that frame, we have followed and advocated a radical open access approach that fuels interaction and visibility of such cooperative endeavors for the public good.
A qualidade da atenção primária à saúde sob a perspectiva da pessoa idosa: a realidade de um município do Brasil Central
Authors: Silva Leidiane Soares da , Andrade Sonia Maria Oliveira de , Batiston Adriane Pires , Medeiros Arthur de Almeida
Published: February 2025

Resumo Objetivo Avaliar a qualidade da Atenção Primária à Saúde na perspectiva dos usuários idosos de Rio Brilhante, MS, Brasil. Método Pesquisa de delineamento transversal de análise quantitativa e amostra representativa do Brasil Central (n= 345 pessoas idosas). Os dados foram coletados utilizando o questionário do instrumento PCATool-Brasil (Primary Care Assesment Tool), validado nacionalmente pelo Ministério da Saúde. Para análise de dados, foram utilizados procedimentos de análise descritiva com apresentação dos resultados por meio das frequências absolutas e relativas para as variáveis categóricas e através das medidas de tendência central e variabilidade, desvio padrão, para as variáveis contínuas. A análise inferencial foi realizada por meio do teste de regressão logística com apresentação da Odds Ratio, com valor de p<0,20. Resultados Constatou-se maior utilização dos serviços oferecidos pelos usuários do sexo feminino de 69,7%. O escore essencial da APS no município, avaliação da assistência oferecida no nível primário, obteve média 6,94 acima da nota de corte de 6,6, classificado como qualidade alta. O escore geral foi avaliado em 6,27, porém, considerado baixo pelo instrumento. Conclusão A qualidade da APS segundo o escore geral é baixa, O escore essencial é alto, indicando que os serviços de saúde da APS do município são orientados por seus atributos promovendo maior satisfação dos usuários com impacto positivo no estado de saúde da população.
Polypharmacy in the Brazilian elderly population and associated chronic non-communicable diseases: a nationwide study
Authors: Licoviski Pamela Taina , Blanski Clóris Regina , Farago Paulo Vitor , Soares Gabriella Barreto , Bordin Danielle
Published: February 2025

Abstract Objective To analyze the prevalence of polypharmacy and the chronic non-communicable diseases (NCDs) associated with polypharmacy among Brazilian elderly based on data from the National Health Survey (PNS). Method This was an observational, cross-sectional, quantitative, and exploratory study utilizing secondary data from public domain sources, derived from the most recent population-based survey, the PNS, conducted in 2019. The study population comprised older adults from across Brazil who were interviewed in the PNS. Polypharmacy was used as the dependent variable, while NCDs were considered as independent variables. The entirety of the information contained in the database (n=293,726) was considered. After applying exclusion criteria, the final sample comprised 31,633 individuals. Results The sample predominantly consisted of males, with a mean age of 70.8 years, who were married, White, literate, had completed high school, and reported a mean monthly income of R$1,928.59. Among the older adults, the prevalence of polypharmacy was 23.8% (n=7,534). All evaluated NCDs were associated with polypharmacy (p<0.05), and individuals with at least one NCDs were more likely to use polypharmacy compared to those without NCDs (p<0.05). Conclusion The prevalence of polypharmacy was high and demonstrated an association with NCDs among older adults across the five regions of Brazil, with a negative impact. This highlights the need for public policies aimed at reducing or preventing polypharmacy and its associated risks.
I Brazilian guideline on hypertension in dialysis of the Brazilian Society of Nephrology
Authors: Rodrigues Cibele Isaac Saad , Ferreira-Filho Sebastião Rodrigues , Moura Ana Flávia de Souza , Poli-de-Figueiredo Carlos Eduardo , Silva Dirceu Reis da , Polacchini Fernanda Salomão Gorayeb , Almeida Fernando Antônio de , Pinheiro Maria Eliete , Bezerra Rodrigo , Paula Rogério Baumgratz de , Peixoto Aldo José , Figueiredo Ana Elizabeth Prado Lima , Feitosa Audes Diógenes Magalhães , Machado Carlos Alberto , Amodeo Celso , Mion Junior Décio , Muxfeldt Elizabeth Silaid , Silva Giovanio Vieira da , Moura-Neto José Andrade , Pazeli Júnior José Muniz , Lotaif Leda Daud , Drager Luciano F. , Martín Luis Cuadrado , Bortolotto Luiz Aparecido , Bastos Marcus Gomes , Malachias Marcus Vinícius Bolívar , Moreira Marcos Vinícius Paiva Cavalcanti , Canziani Maria Eugenia Fernandes , Miranda Roberto Dischinger , Franco Roberto Jorge da Silva , Pecoits Filho Roberto , Mulinari Rogerio Andrade , Elias Rosilene Motta , Barroso Weimar Kunz Sebba , Nadruz Wilson
Published: February 2025

Abstract Hypertension in dialysis patients (HTND) has a high prevalence, affecting at least 80% or more of patients, and its management in the nephrology practice is heterogeneous and often empirical. Knowing how to define, understand the pathophysiology, diagnose, monitor and treat with lifestyle changes, and adjust antihypertensive drugs to achieve the recommended blood pressure (BP) target - to reduce morbidity and mortality - requires specific knowledge and approaches within the contexts of hemodialysis (HD) and peritoneal dialysis (PD). This document is the first guideline of the Brazilian Society of Nephrology, developed by the departments of Hypertension and Dialysis. It aims to guide physicians who provide care in dialysis centers on how to manage patients with HTND, in a comprehensive and individualized manner, based on the critical appraisal of the best available scientific evidence. When such evidence is scarce or unavailable, the opinion of specialists should be recommended. The different topics covered include HTND definition (pre-HD BP ≥ 140/90 mmHg and post-HD BP ≥ 130/80 mmHg), epidemiology, and pathophysiology; diagnosis of HTND preferably with BP measurements outside the dialysis setting (BP ≥ 130/80 mmHg); complementary assessment; blood pressure targets; non-pharmacological treatment; use of the most appropriate antihypertensive medications; special situations; and complications of HTND, predominantly cardiovascular ones.
Hiperparatireoidismo secundário devido à doença renal crônica e acesso ao tratamento clínico e à paratireoidectomia no Brasil: uma pesquisa nacional
Authors: Pelepenko Lauter Eston , Louça Marcelo Giacomini , Fausto Tarcísio , Bucharles Sergio Gardano Elias , Custódio Melani Ribeiro , Lucca Junior Leandro , Barreto Fellype de Carvalho , Carvalho Aluízio Barbosa , Jorgetti Vanda , Moura Neto José Andrade , Oliveira Rodrigo Bueno de
Published: February 2025

Resumo Introdução: A doença renal crônica (DRC) pode levar ao hiperparatireoidismo secundário (HPTS) e seu tratamento baseia-se no controle da hiperfosfatemia, hipocalcemia e níveis séricos de paratormônio (PTH). Apesar dos avanços no tratamento do HPTS, a falha terapêutica é frequente, e pacientes com DRC em diálise demandam paratireoidectomia (PTx). Objetivo: Atualizar a pesquisa de 2011, estimar a prevalência atual de HPTS nos centros de diálise brasileiros, verificar acesso a medicamentos e identificar obstáculos para a realização de PTx. Métodos: Questionário enviado às unidades de diálise ativas. Os resultados foram compilados e comparados estatisticamente (p < 0,05). Resultados: 114 unidades responderam com sucesso ao questionário, a maioria da região sudeste. Aproximadamente 9% dos indivíduos (23.535) apresentaram níveis séricos de PTH acima de 1.000 pg/mL (10,7% foram relatados em 2011). Um número considerável das dificuldades relatadas indicou disponibilidade limitada de medicamentos essenciais para o manejo do HPTS e complicações associadas. Ressalta-se que apenas 2,7% dos indivíduos foram submetidos à PTx. Para aqueles com indicação de PTx, o tempo de espera pelo procedimento foi superior a dois anos em 28% dos casos. As principais barreiras à realização da PTx foram relatadas como o longo tempo de espera pelo procedimento, a escassez de cirurgiões de cabeça e pescoço e a falta de leitos para internações hospitalares. Conclusão: Alguns aspectos melhoraram desde 2011. Entretanto, o HPTS continua altamente prevalente no Brasil, e um número significativo de indivíduos não tem acesso à PTx ou enfrenta longos períodos de espera por esse procedimento cirúrgico, além de dificuldades substanciais para obter tratamento clínico.
Jean-Christophe Le Coze and the study of socio technological risks
Authors: Hurtado Sandra Lorena Beltran , Simões Raoni Rocha , Almeida Ildeberto Muniz de , Vilela Rodolfo Andrade de Gouveia , Le Coze Jean-Christophe
Published: February 2025

Abstract Jean-Christophe Le Coze has been working for the INERIS National Institute for Industrial Environment and Risks in France for more than 20 years now. He started his career as a safety engineer, but very quickly moved into the human and social sciences. From the beginning of his career, he was brought in with the idea that engineers could incorporate Human Factors in their visions and practices of safety. He then spent almost a year at the Technical University of Delft in the Safety Science Group. After that there was an accident in a French pyrotechnic plant in 2003, and Jean-Christophe Le Coze, in charge of the investigation, wrote a report showing the importance of the Human and Organisational Factors behind this event. It was a moment in France during which high-hazardous plants were questioned and were at the heart of the political agenda in terms of developing adequate regulation. Since then, he has contributed significantly to the advancement of knowledge in the safety area. One of his publications “Thirty years of accidents: the new face of socio-technological risks” was translated into Portuguese and published in 2023. This interview highlights the main concepts of the book and current challenges for accident prevention.
Tuberculose na população privada de liberdade: epidemiologia e análise espacial entre 2014 e 2020
Authors: Souza Pablo Cristiano de , Couto Rodrigo de Macedo , Lacerda Alec Brian , Silva Pãmela Rodrigues de Souza , Espinosa Omar Ariel , Lima Jaqueline Costa
Published: February 2025

Resumo Objetivo: Descrever a epidemiologia e distribuição espacial da tuberculose na população privada de liberdade no estado de Mato Grosso, no período de 2014 a 2020. Método: Estudo descritivo, com análise espacial da distribuição geográfica da tuberculose. Estimaram-se as incidências, avaliando suas distribuições nos municípios de Mato Grosso - Brasil através da análise de aglomerados espaciais Gi*. Resultados: 14,0% (n=1.003) dos 7.201 casos de tuberculose notificados entre 2014 e 2020 em pessoas com maioridade ocorreram na população privada de liberdade. A incidência de tuberculose nesta população passou de 3.261,1 para 722,3 casos/100 mil-habitantes entre 2014 e 2020. Pessoas de 18-39 anos, do sexo masculino, de raça/cor parda e com ensino fundamental incompleto foram associadas à maior ocorrência de tuberculose. Conclusão: Aglomerados de alto risco foram encontrados nas regiões central e sul do estado, próximos de municípios com maior número de presídios. O estudo contribui na formação de políticas públicas de saúde e estratégias de controle da Tuberculose.
Fatores associados aos sintomas de depressão de pessoas com insuficiência cardíaca
Authors: Melo Débora Ananias de , Frazão Maria Cristina Lins Oliveira , Ferreira Gerlania Rodrigues Salviano , Silva Cleane Rosa Ribeiro da , Viana Lia Raquel de Carvalho , Lima Riane Barbosa de , Costa Katia Neyla de Freitas Macedo
Published: February 2025

RESUMO Objetivo: Identificar os fatores associados aos sintomas de depressão de pessoas com insuficiência cardíaca. Método: Estudo transversal com abordagem quantitativa, realizado com pessoas com diagnóstico médico de insuficiência cardíaca em seguimento no ambulatório de cardiologia de um hospital universitário do município de João Pessoa, Paraíba, Brasil. Os dados foram coletados no período de dezembro de 2021 a maio de 2022, utilizando-se um instrumento para caracterização sociodemográfica e clínica e o Patient Health Questionnaire-9. Análise por estatística descritiva e inferencial. Resultados: Dos 89 participantes, 32,6% referiram presença de sintomas de depressão. Na associação entre as variáveis, os sintomas de depressão associaram-se ao sexo (p=0,004), autoavaliação da saúde (p=0,042), classe funcional (p<0,001) e internação por insuficiência cardíaca (p=0,044). Conclusão: Tais achados podem embasar novas pesquisas e intervenções de enfermagem com o intuito de proporcionar uma assistência integral e de qualidade.
ENFOQUES DE APRENDIZAJE DE KOLB, HERRMANN Y GARDNER EN EL PROCESO ENSEÑANZA-APRENDIZAJE
Authors: Puente Balcázar Reyes Guadalupe , Arellano Díaz Sara Marcela , Vázquez Rojas Silvia
Published: February 2025

Se presentan tres modelos de aprendizaje: el aprendizaje experiencial de David A. Kolb, los cuatro cuadrantes cerebrales de William "Ned" Herrmann, y las inteligencias múltiples de Howard Gardner. Cada modelo proporciona una perspectiva distinta sobre cómo los alumnos aprenden, procesan e interpretan la información. El objetivo de este artículo es identificar y analizar las características de los alumnos para poder proponer estrategias pedagógicas que mejoren el aprendizaje de los estudiantes. Con apoyo de un enfoque comparativo, se busca destacar los aspectos más relevantes para cada teoría; destacando las diferencias entre cada tipo de alumno con el uso de tablas comparativas, las cuales nos ayudan a ubicar los distintos estilos de aprendizaje para con ello contribuir en la mejora pedagógica y didáctica de los docentes dentro y fuera del aula.
Study of hardware methods impact on the physical properties of hyaluronic acid-based tissue fillers in experiment
Authors: Mishurinskaya E.A. , Karpova E.I. , Terent’ev A.Yu. , Supil’nikov A.A. , Lopanchuk P.A. , Sepp V.V. , Bakulin K.S. , Ubushaev S.V. , Ovcharenko T.A.
Published: February 2025

The article is devoted to studying the change of physical and chemical properties of hyaluronic acid-based tissue fillers after focused ultrasound and radio-frequency spectrum exposure. The physical properties of tissue fillers (dynamic viscosity, water absorption, cohesiveness) before and after focused ultrasound exposure, as well as radio-frequency spectrum are described. Experiments were carried out in vitro in a polyethylene bag, as well as on a cadaver material, anatomical bioblocks of human origin at the Multidisciplinary Accreditation and Simulation Center of the Institute of Anatomy and Morphology named after Academician Yu. M. Lopukhin of the Pirogov RNRMU with the support of the MHICPE, companies producing hyaluronic acid-based tissue fillers, «National Company of Beauty» and KIT-MED companies. The obtained data show that the physical and chemical properties of hyaluronic acid-based tissue fillers have changed after hardware methods exposure. According to the ultrasound data, it is clearly seen that the volume of hyaluronic acid-based tissue filler decreases and its fragmentation occurs in some cases due to the impact of physical factors. This fact requires further investigation.
Clinical features of severe acne and genetic determinants of therapeutic efficacy of systemic isotretinoin
Authors: Demina O.M.
Published: February 2025

Objective. To study the clinical features of severe acne and pharmacogenetic mechanism of resistance to systemic therapy. Material and methods. A prospective open-label nonrandomized single-center comparative study was performed at the Department of Skin Diseases and Cosmetology of the Pirogov RNRMU in 2011—2024. The study included 388 subjects divided into 2 groups: study —309 patients with severe acne, comparison group — 79 conditionally healthy persons. Molecular genetic diagnosis was carried out by the method of next-generation sequencing (NGS) with the use of targeted multi-gene panels at the Laboratory of Molecular Biology of the Dmitry Rogachev NRCPHOI. Statistical processing of results was done by means of the Python language (Python 3.11.). Results. It has been established that the clinical features of severe acne are 2 clinical forms, namely severe papulopustulous acne, moderate nodular acne and severe nodular acne, acne conglobata in approximately equal proportion (49.5 and 50.5%, respectively). Thus, the pattern has been revealed: women suffered mainly from the first clinical form, men — from the second. We have demonstrated for the first time that the PTCH1 (rs574688) in intron, ABCA1 (rs2777801) in intron, RET (-(. ) in introns increase the risk of acne development by 2.85, 2.54 and 2.33 times, respectively (p<0.05); severe acne is associated with GA SMPD1 rs1050239 genotype. Strong inverse correlation between the GG SMPD1 rs1050239 genotype and the A SMPD1 rs1050239 allele and moderate inverse correlation between the GC PTCH1 rs574688 and GG SMPD1 rs1050239 genotypes have been found. Conclusion. Detection of the specific loci of genes, regulation of the activation of response on retinoic acid and its derivatives can be pharmacogenetic markers of acne resistance.
Comparison of dermoscopic picture of the foci of localized scleroderma and tumor-associated localized scleroderma
Authors: Kazakova P.O. , Zhukova O.V. , Malyarenko E.N. , Denisova E.V. , Radionova E.E. , Khamaganova I.V. , Golousenko I.Yu.
Published: February 2025

Background. Digital dermoscopy is actively used in the diagnosis of various diseases of dermatological profile. Non-invasiveness, painlessness and performance rate of this method facilitates the application of dermoscopy at the initial attendance, that optimizes the diagnostic process. Timely routing of patients is extremely important in diseases associated with the oncological process. Objective. To compare the dermoscopic picture of the foci in patients with tumor-associated localized scleroderma and in patients with localized scleroderma. Material and methods. Digital dermoscope was used for investigation of 2 groups of patients. We examined 25 patients with tumor-associated scleroderma: 24 (96%) women and 1 (4%) men. The group with localized scleroderma included 25 patients: 23 (92%) women and 2 (8%) men. Mean age of the examined — 63.7 years. Results. A combination of 3 dermoscopic features has been noted in patients with tumor-associated localized scleroderma. The foci are characterized by less distinct dermoscopic features in the number of 2—3 in dermoscopy of all lesion foci. Conclusion. Patients with tumor-associated localized scleroderma have signs of inflammation in the foci. Further research should be performed to determine the presence of specific dermoscopic signs in this pathology.
Prevention of herpetic infection during lip dermopigmentation procedure
Authors: Sazhina A.O. , Ustyuzhanin A.V.
Published: February 2025

Background. Dermopigmentation is currently one of the most frequently performed invasive cosmetic procedures. Traumatization of the trigeminal nerve fibers during the process of dermopigmentation can contribute to the recurrence of herpes simplex virus type 1 (HSV-1) and affect the healing process, aesthetic result, increase the risk of HSV-1 transmission to healthy people. The majority of specialists in the field of permanent tattoo do not have medical education, are not aware of the mechanisms of virus reactivation and optimal measures for the prevention of virus transmission, that determines the study’s relevance. Objective. To reveal the reactivation rate of herpes labialis after lip dermopigmentation, to evaluate the effectiveness of preventive medication of antiherpetic drugs before the procedure, to provide protocol for prevention of HSV-1 recurrences. Material and methods. A questionnaire survey of 206 respondents, retrospective study of medical history and clinical picture for reactivation of HSV-1 in the form of herpes labialis in patients after the procedure of lip dermopigmentation were performed. Results. The lip dermopigmentation procedure promotes reactivation of HSV-1 in the form of herpes labialis in 39% of patients. Preventive medication of antiviral drugs a few days before the procedure reduces the probability of recurrence. Antiviral prevention has a dose-dependent effect, which is determined by the choice of regimen for preventive medication of drugs and should be based on the prediction of the infection reactivation risk relative to the patient’s medical history. Valacyclovir may be recommended as an agent of choice. Conclusion. The procedure of lip dermopigmentation increases the risk of HSV-1 transmission to healthy people. It is advisable to carry out the prevention by oral antiherpetic drugs to all users of this service, that will reduce the probability of spreading the causative agent of viral infectious pathology.
Psychometric evaluation of the Quick Screening Procedure for Referral to Occupational Therapy (QSPOT) for five year olds with and without barriers to learning
Authors: Vial Lauren Jeannie , Franzsen Denise
Published: February 2025

ABSTRACTIntroduction: Adjustments made to the Quick Screening Procedure for Referral to Occupational Therapy (QSPOT) required further validation of the test. This assessment, which was developed in South Africa, is used to screen motor, praxis and sensory-perceptual performance skills related to intrinsic barriers to learning in 4 to 6 year old children. Method: The aim of this study was to determine the accuracy of the QSPOT in identifying intrinsic barriers to learning in 5 year olds, as well as the concurrent criterion validity of the QSPOT compared to the Movement ABC - 2nd Edition (MABC-2), and the Developmental Test of Visual-Motor Integration - 6th Edition (DTVMI-6) (VMI and Visual Perception subtests). Eighty-three learners in mainstream schools and Learners with Special Education Needs (LSEN) schools were assessed with all three tests.Results/Findings: Acceptable specificity was found for the QSPOT; however, sensitivity was unacceptably low. Adequate concurrent criterion validity was found between the QSPOT Total Score and the MABC-2 Total Score, as well as between the QSPOT and the DTVMI-VMI for Age-band 1 (5 years 0 months to 5 years 5 months), but not for Age-band 2 (5 years 6 months to 5 years 11 months). Conclusion: The QSPOT accurately identifies learners without barriers to learning, but may under-identify those with barriers to learning. Strong concurrent criterion validity of the QSPOT to the DTVMI-VMI and MABC-2 indicate that motor, praxis and sensory-perceptual performance skills deficits were all identified within Age-band 1.Key words: Intrinsic barriers to learning, motor and praxis performance skills, sensory-perceptual performance skills, screening, screening procedures, sensitivity, specificity, concurrent criterion validity
Análise dos Indicadores de Transporte da ISO 37122
Authors: Costa Laura Meira , Silva Thaísa Leal da
Published: February 2025

The use of digital technologies has become increasingly present in urban spaces, and the management of the generated data aims to improve the efficiency of urban services, optimizing resources and increasing the quality of life of its inhabitants. In this sense, the objective of this article is to analyze the Transportation indicators of NBR ISO 37122 - Sustainable cities and communities - Indicators for smart cities, in the context of the city of Passo Fundo, in Rio Grande do Sul. In addition, it intends to investigate the level of development of the city in relation to these indicators, verifying those that lack investment by public management, and which initiatives the city has implemented or plans to implement aiming at improving the analyzed indicators. In the research methodology, a bibliographic review was initially carried out on the themes of urban indicators, Smart Cities, Transportation and ISO 37122, soon after, a data survey was carried out in relation to the Transportation indicators of ISO 37122 and the city of Passo Fundo-RS. Based on the results, it was possible to observe the urban development of the municipality in relation to the indicators analyzed, as well as to observe the results of urban actions implemented in the scope of transportation and urban mobility. Furthermore, the relevance of data collection was determined with regard to urban indicators, which are important tools for the planning and development of cities, being decisive in directing public policies and investments by urban management.
The Effect of Anxiety, Depression, Social Support and Clinical Features on Hope in Kidney and Liver Transplant Recipients
Authors: Esra Şeker , Gülsüm Nihal Çürük , Özgül Karayurt
Published: February 2025

Aim: This study aimed to examine the effects of anxiety, depression, social support, and clinical features on hope among kidney and liver transplant recipients.
Method: This study used a descriptive cross-sectional design, and the study sample included 192 kidney (n:100) and liver (n:92) transplant recipients. A sociodemographic and clinical characteristics form, The Hospital Anxiety and Depression Scale, The Perceived Available Support Scale, and The Herth Hope Index were used to collect data. Data were collected through face-to-face interviews and patient records between 15 August and 30 December 2020. Numbers, percentages, mean values, and multiple regression analyses were used to evaluate data.
Results: The mean score on The Perceived Available Support Scale was a significant, positive predictor of the mean score on The Herth Hope Index (β = 0.386, SE = 0.056; p < 0.001), but the mean score on The Hospital Anxiety and Depression Scale was a significant, negative predictor of the mean score on The Herth Hope Index (β = -0.390, SE = 0.115; p < 0.001). The time elapsing after transplantation (β = -0.219, SE = 0.009, p = 0.006) and transplants from cadavers (β = -0.201, SE = 0.886; p = 0.004) were also significant, negative predictors of hope in kidney and liver transplant recipients.
Conclusion: The results showed that a significant portion of the patients were at risk of anxiety and depression and had moderate social support after transplantation. Besides, the level of anxiety did not affect hope and as social support increased, so did hope.
Representación y Emociones: Discursos de Candidatas Independientes en la Convención Constituyente Chilena
Authors: Gartenlaub Andrea , Rodolfo Rodolfo , Alfaro Andrea
Published: February 2025

El devenir político chileno, con un estallido social y la crisis de los partidos tradicionales, permitió la aparición de candidaturas independientes de mujeres gracias a la introducción de fórmulas de paridad en la elección de representantes en el proceso constituyente 2020. Este trabajo explora los resultados de uno de estos procesos. Para ello se desarrolló un diseño de investigación cualitativa en que se entrevistó mediante entrevistas en línea a ocho candidatas, sin militancia partidista, residentes de dos provincias semi rurales de la región de Valparaíso, quienes relataron sus experiencias de campaña. La información recogida se analizó mediante la identificación de categorías, según la teoría fundamentada, y la identificación inferencial de las emociones latentes en la explicitación verbal. Los resultados evidenciaron que la gestión de la emoción puede entenderse como un obstaculizador para la participación de mujeres en política. Algunas de las emociones aquí descritas emergieron como un factor que impactó decisivamente en las trayectorias de las candidatas, en términos de continuación o abandono de la política institucionalizada. Este trabajo evidencia cómo la perspectiva subjetiva influye en la baja incorporación de mujeres en cargos de representación pública.
From Digital Divide to Employment Equity: How Digitalization Affects Women's Involvement in the Workforce in OECD Countries
Authors: Tunçsiper Çağatay
Published: February 2025

Purpose: This study examines how digitization affects women's employment in 22 OECD nations that were chosen for their varied political, economic, and digital traits. To better understand how technological adoption interacts with socioeconomic factors to influence employment outcomes, the study will look at the short-term and long-term effects of digitalization on women's labour force participation. Design/Methodology: A strong panel data structure is used, with variables like the fertility rate (F), GDP per capita (GDP), internet usage (WEB), mobile cellular subscriptions (MB), and women's labour force participation (W) for the years 2000–2021. Utilizing econometric methods such as unit root tests, co-integration analysis, and causality models, the study aims to identify dynamic connections between women's employment and digitization. Findings: The results show that women's labour market engagement is greatly increased by digitalization, as seen by the rise in the use of mobile and internet gadgets. Results from co-integration show that women's employment and digitalization have a consistent, long-term relationship. Originality: This study highlights the revolutionary potential of digitization in establishing gender-neutral employment markets and provides fresh insights into the relationship between digitalization and gendered labour market outcomes. The study adds to the conversation on creating inclusive digital economies worldwide by being in line with the Sustainable Development Goals, especially those on gender equality and decent labour.
Editorial: Gendered Cultures in Platform Economies—Entertainment, Expertise and Online Selfhood
Authors: Kompatsiaris Panos , Álvares Cláudia , Van Bauwel Sofie
Published: February 2025

This thematic issue examines the gendered dimensions of platform economies, focusing on the construction of gendered online selfhood. Through the affordances of social media platforms, users expand the range of topics and content accessible to the public, simultaneously exposing these subjects to increased visibility and potential debate. Platforms such as TikTok, YouTube, Instagram, Twitch, X, and Telegram enable anyone to create channels and publicize content on virtually any topic, fostering niche communities. In other words, platforms, driven by their pursuit of attention, time, and data, cannot be analyzed solely through a business or organizational lens. The economic dimension is intertwined with cultural formations—beliefs, values, and identity constructions—which carry an anthropological dimension. In this thematic issue, we are particularly interested in the gendered aspects of this intertwining.
VISUAL PROOF OF FACTORIZATION FORMULA-PRACTICAL GUIDANCE FOR STUDENTS
Authors: Fukuda Chuya , Sugawara Koki
Published: February 2025

In this paper, we report practical guidance for students on visual proof of factorization formula. First, we use area to guide students on factorizing quadratic equations. Based on this, next we use volume to guide students on factoring cubic equations. Finally, students try a visual proof of factoring a cubic equation. The results of the challenge came positive.
The course of pregnancy and childbirth in patients with uterine fibroids
Authors: Dobrokhotova Yulia E. , Ilyina Irina Yu. , Hachatrian Aznar S. , Narimanova Metanat , Ibragimova Gamila M. , Platova Elena S , Kauseva Olga I.
Published: February 2025

Uterine fibroids are a common disease against which pregnancy can occur. In some cases, uterine fibroids do not prevent pregnancy, but can contribute to the development of complications during pregnancy and childbirth. The effect of fibroids on the onset and course of pregnancy is determined by the localization, size and number of nodes. Currently, the age of women planning pregnancy is gradually increasing, which increases the likelihood of uterine fibroids in pregnant women. Therefore, the main surgical direction is to perform organ-preserving operations in order to prepare patients for pregnancy and reduce the risks of complications. What kind of treatment can lead to the optimal result, the least number of complications, and a reduction in symptoms has not been established to date, and depends on many factors and requires careful selection of patients for a particular treatment method.
Fortalezas del ecoturismo en Tamaulipas:
Authors: Tovar Cabañas Rodrigo , Jaramillo Escobedo José Vicente , Rangel Blanco Lidia
Published: February 2025

La importancia de este trabajo reside en que, tras la pandemia de 2020, el sector turístico ha sido fuertemente impactado en su participación dentro del Producto Interno Bruto Nacional, siendo el ecoturismo y el turismo rural una opción viable para las nuevas dinámicas espaciales que ha de experimentar esta actividad recreativa. Por lo que esta investigación tuvo como objetivo, diseñar y estimar el primer índice de potencialidad turística de Tamaulipas, México, para documentar las fortalezas del ecoturismo y el turismo rural a escala municipal y de ese modo aportar elementos para caracterizar el rumbo que pudieran seguir algunas agendas ecoturísticas de dicho estado. Es de advertir que el tratamiento metodológico partió de un cociente de localización alimentado con bases de datos nacionales e internacionales, así como de consultas en redes sociales. Dentro de los resultados más apremiantes tenemos que, dos municipios son los más óptimos para este tipo de turismo: Madero y Tampico; luego están otros dos municipios de la zona sur y centro que presentan óptimas condiciones para el turismo rural o el ecoturismo: Victoria y Nuevo Morelos; les siguen algunos municipios de la porción sur: Mante, Antiguo Morelos y Altamira.  Estos resultados fortalecen a la teoría de la planificación integral del turismo puesto que el índice condensa de forma holística aspectos físicos, económicos, sociales y culturales; a la teoría del turismo rural familiar, puesto que las diversas temporadas de trabajo de campo contribuyeron a involucrar a los habitantes en actividades turísticas relacionadas con su cultura y su entorno natural; y a la teoría del desarrollo turístico sostenible al priorizar una gestión adecuada de áreas naturales como la Laguna del Carpintero.