bluuebunny/crossref_metadata_2025 huggingface dataset:
Transformando la educación desde la gestión educativa: hacia un cambio de mentalidad
Authors: Jimenez-Cruz Jenny
Published: June 2020

Este artículo plantea la transcendencia sobre la organización del trabajo en las instituciones de educación superior, proponiendo la generación de nuevas estructuras que reparen las falencias existentes alrededor de la falta de planeación, direccionamiento y gestión, que bloquea sustancialmente a los integrantes de la comunidad educativa. Por tanto, en este documento se exponen ideas asociadas a la profesionalización de acciones educativas comparadas con la elaboración de tareas en un entorno laboral, a partir de un proyecto pedagógico-organizacional que integra los rasgos de identidad del modelo de administración y la gestión educativa, la estructura de un curso de formación para directivos y profesores sobre la apertura del aprendizaje y la innovación y la creación de la estrategia pedagógica y organizacional para mejorar las prácticas de dirección. La metodología utilizada se enfocó particularmente en la observación de hechos y realidades (proyectiva-holística) los sujetos y sus relaciones e interacciones en el contexto pedagógico y organizacional.
Análisis de riesgo mediante el método de simulación de Montecarlo aplicado a la inversión pública en el sector educativo peruano: el caso del departamento de Puno
Authors: Inquilla-Mamani Juan , Rodríguez-Limachi Omar Moisés
Published: June 2020

Los Estados en general invierten recursos económicos y financieros con la finalidad de mejorar los servicios educativos en los diferentes ámbitos y contextos. Para este propósito ejecutan proyectos de distintos tipos (infraestructura y de servicios). El objetivo de esta pesquisa es ofrecer un análisis de riesgo en los proyectos de inversión en el sector educación en el departamento de Puno. El estudio se basa en la aplicación del método de simulación de Montecarlo mediante el programa informático Risk Simulator y Crystal Ball. Los resultados indican que, para el proyecto de inversión pública en el sector educación, la probabilidad de que el VANS sea mayor que cero [p (VANS>0)] es de 67,10 %; consecuentemente, la probabilidad de no viabilidad del proyecto de inversión pública es de 32,9 %; y la probabilidad de que la TIRS sea mayor que la tasa social de descuento [p (TIRS>8 %)] es del 67,10 %. Finalmente, se puede concluir que, con base en los hallazgos encontrados, es recomendable aplicar el análisis de riesgo utilizando el método de Montecarlo en proyectos de inversión pública en el sector educación para decidir la viabilidad económica y social del proyecto.
Faecal Microbiota Transplantation in Inflammatory Bowel Disease: Current Concepts and Future Challenges
Authors: Zatorski Hubert , Nakov Radislav
Published: June 2020

Dysbiosis has been repeatedly observed in inflammatory bowel disease (IBD) and is now
recognized as an essential factor in the gut inflammatory process. IBD is a significant burden to
health-care systems, mainly due to treatment-related costs. Available treatments have several limitations:
up to 30% of patients are primary non-responders, and between 10 and 20% lose response per
year, requiring a dose-escalation or a switch to another biologic. Hence, the current IBD treatment is
not sufficient, and there is an urgent need to introduce new therapies in the management of these patients.
Recently, the correction of dysbiosis has become an attractive approach from a therapeutic
point of view. Faecal microbiota transplantation (FMT) appears as a reliable and potentially beneficial
therapy in IBD patients. There is developing data that FMT for mild-to-moderately active UC is a safe
and efficient therapy for the induction of remission. However, the current studies have different designs
and have a short follow up, which makes clinical interpretation significantly difficult. There is a
need for RCTs with a well-defined study cohort using FMT for the therapy of CD patients. The location,
behavior, and severity of the disease should be taken into account. The goal of this manuscript is
to review the data currently available on FMT and IBD, to explain FMT principles and methodology
in IBD patients and to discuss some unresolved issues.
[Bmim]HSO4 loaded on Graphene Oxide: A Green and Retrievable Nanocatalyst for the Synthesis of Polysubstituted Pyrroles; Some of Which are Fluorinated
Authors: Shekarchi Maral , Behbahani Farahnaz K.
Published: June 2020

1-Butyl-3-methylimidazolium hydrogen sulfate [bmim]HSO4 as a non-halogenated ionic liquid was loaded on graphene oxide ([bmim]HSO4/GO) and employed as a green, reusable, solid nanocatalyst for the preparation of polysubstituted pyrroles in the presence of amines (such as benzeneamine, 2-amino-4-methylthiazole, adenine (9H-purin-6-amine)), benzaldehydes or cinnamaldehyde or furfural, 1,3-dicarbonyl compounds, and nitromethane at 90-95°C. The advantages of this protocol are the synthesis of some novel polysubstituted pyrroles containing fluorine atoms, thiazole and adenine nuclei that are very important in pharmaceutical and drug discovery research in comparison to previously reported results.
High Performance Thin Layer Chromatography (HPTLC) for the Investigation of Medicinal Plants
Authors: Gökbulut Alper
Published: June 2020

Background:

Chromatographic techniques, such as TLC basically and HPLC, GC,
HPTLC, equipped with various detectors are most frequently used for the qualitative and quantitative
examination of herbals.

Method:

An overview of the recent literature concerning the usage of HPTLC for the analysis of
medicinal plants has been carried out.

Results:

During the last decade/s, HPTLC, a modern, sophisticated, and automatized TLC technique
with better and advanced separation efficiency, detection limit, data acquisition, and processing, has
been used for the analysis of herbal materials and preparations since the rapid development of technology
in chromatography world. HPTLC with various detectors is a powerful analytical tool, especially
for the phytochemical applications, such as herbal drug quantification and fingerprint analysis.

Conclusion:

In this review, a latest perspective has been established and some of the previous studies
were summarized for the usage of HPTLC in the analysis of herbal remedies, dietary supplements,
and nutraceuticals.
High Parasitic Contamination of Soil Samples in the North of Iran: A Potential Risk of Parasitic Infection for Tourists
Authors: Haghparast-kenari Beheshteh , Nayeri Tooran , Sarvi Shahabeddin , Rahimi Mohammad Taghi , Ahmadpour Ehsan , Sharif Mehdi , Daryani Ahmad
Published: June 2020

Background:

Soil-transmitted parasites (STPs) are significant intestinal parasites that infect
humans and animals and impose considerable burdens on human society and animal husbandry
industries. Therefore, the present study aimed to determine the prevalence of parasitic elements
of soil samples collected from the north of Iran.

Methods:

A total of 256 soil samples were collected from public parks, public places, vegetable
gardens, sand heaps, and shadow areas near houses in the north of Iran and examined using the sucrose
flotation method.

Results:

Out of 256 examined samples, 131 (51.2%) showed parasitic contamination, including larvae
(43%), oocysts (14.1%), and different eggs (6.6%). According to the results, the most and least
common parasites observed in the samples were larvae (43%), as well as Toxascaris leonina, and
Trichuris trichiura (0.4%), respectively. Moreover, the most and least contaminated locations were
sand heaps (62.5%) and shadow areas near houses (45.6%), respectively. Regarding cities,
Behshahr (68.3%) and Sari (67.5%) had the highest contaminated soil samples, whereas Chalus
(37.5%) showed the lowest contamination. On the other hand, rural samples showed more contamination
compared to urban areas (P< 0.05).

Conclusion:

The findings of the present study indicate that the overall prevalence of STPs in examined
areas and highly contaminated soil samples can be considered as a potential source of human
contamination particularly tourists with STPs.
Analisis kesiapan mahasiswa jurusan pendidikan fisika menggunakan e-learning dalam situasi pandemi Covid-19
Authors: Setiaji Bayu , Dinata Pri Ariadi Cahya
Published: June 2020

Efektivitas dari penerapan e-learning di perguruan tinggi pada situasi pandemi Covid 19 dipengaruhi beberapa faktor. Faktor yang paling penting adalah kesiapan mahasiswa menggunakan ­e-learning dalam proses perkuliahan. Tujuan dari penelitian ini adalah untuk mengetahui tingkat kesiapan mahasiswa pendidikan fisika dalam menggunakan e-learning. Dengan mengetahui tingkat kesiapan mahasiswa, dosen dan pemangku kebijakan dapat mempersiapkan kebijakan pengembangan lebih lanjut. Metode yang digunakan adalah survei. Kesiapan mahasiswa menggunakan e-learning diukur dengan menggunakan angket kesiapan mahasiswa. Angket kesiapan mahasiswa yang dikembangkan berdasarkan pada instrumen model Aydin dan Tasci. Angket kesiapan mahasiswa ini memiliki 25 pernyataan dengan 4 indikator. 75 mahasiswa pendidikan fisika dilibatkan dalam penelitian ini. Hasil pengisian angket dianalisis dengan menggunakan metode suksesif interval kemudian dikategorikan ke dalam skala penilaian kesiapan e-learning. Hasil penelitian menunjukkan bahwa mahasiswa Jurusan Pendidikan Fisika UNY termasuk dalam kategori siap pada 3 indikator dan tidak siap pada 1 indikator. Hal ini dapat dijadikan evaluasi bagi para dosen dan pemangku kebijakan agar kesiapan mahasiswa dapat lebih ditingkatkan.    Analysis of e-learning readiness on physics education students during Covid-19 pandemic AbstractThe effectiveness of e-learning implementation in University during Covid-19 Pandemic is depending on several factors. The most important factor is the readiness of students using e-learning in the studying process. The aim of this research is to know physics education student’s readiness in using e-learning. By knowing student’s e-learning readiness, lecturer and stakeholders would be able to prepare further development of e-learning. The method in this research is survey method. Student’s e-learning readiness is measured by using student’s e-learning readiness questionnaire. This questionnaire is developed based on Aydin and Tasci Model. This questionnaire has 25 statements and 4 indicators. 75 students involved in this research. The results are analyzed using successive interval method then categoryzed using e-learning readiness scale. The results show that Physics Education Students of UNY are ready in 3 indicators and not ready in only 1 indicator. This result could be an evaluation for lecturers and stakeholders to increase student’s e-learning readiness.
An Analysis of Artistic Diversity in Hybrid Art Practice among Malaysian Artists
Authors: Anak Michael Valerie , Abd Rahman Khairul Aidil Azlin , Abdul Shukor Shureen Faris , Mohd Ali Noor Azizi
Published: June 2020

This research objective is to analyze the artistic diversity in hybrid art practice among selected Malaysian artists. The paper examines the process of making hybrid artworks where focusing on media diversity and experiment activity. The researchers had used cluster sampling and twenty artists involved to answer the questionnaires. The researchers used bar graph and Principal Component Analysis to analyze the artistic diversity in Hybrid Art. The finding of media diversity shows that Malaysian artists are focusing on mixed media, strength and equipment. Besides, the artists are focusing on subject matter, experiment, influence and research for the finding of experiment activity.   
Keywords: Collaboration, experiment activity, media diversity, hybrid approach.   
eISSN: 2398-4287 © 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.   DOI: https://doi.org/10.21834/ebpj.v5iSI1.2307
Giht, suvremeni pogled na drevnu bolest
Authors: Laktašić Žerjavić Nadica , Hoteit Nadia , Soldo Jureša Dragica
Published: June 2020

Giht je kronična metabolička, no istovremeno i upalna reumatska bolest koja nastaje kao posljedica hiperuricemije i taloženja kristala mononatrijeva urata. Glavni uzrok hiperuricemije je smanjeno bubrežno izlučivanje urata. U patogenezi upalnog odgovora na kristale urata važna je fagocitoza kristala od strane makrofaga koja dovodi do aktivacije inflamasoma NLRP3 i posljedičnog oslobađanja glavnog proupalnog citokina u gihtu interleukina 1β. Neadekvatno liječenje hiperuricemije dovodi do razvoja kroničnog gihta s tofima, značajnih strukturnih oštećenja zglobova s umanjenom funkcionalnom sposobnosti i kvalitetom života. Stoga je važno dugotrajno liječenje usmjereno k cilju održavanja koncentracije urata < 350 umol/L, a u težem obliku bolesti s tofima < 300 umol/L. Akutni artritis u gihtu i akutizaciju kroničnog gihta treba liječiti protuupalnim lijekovima: nesteroidnim antireumaticima, kolhicinom ili glukokortikoidima, uglavnom po monoterapijskom principu. Pacijente s gihtom treba pažljivo pratiti radi udruženih bolesti, posebice bubrežne bolesti, hipertenzije, metaboličkog sindroma i povišenog kardiovaskularnog rizika.
Magnetska rezonancija i kompjutorizirana tomografija u dijagnostici cističnih lezija gušterače
Authors: Petrović Nikša , Matana Kaštelan Zrinka , Grubešić Tiana , Miletić Damir
Published: June 2020

Cistične lezije gušterače su raznovrsna grupa lezija s vrlo širokom histološkom diferencijacijom, od benignih tvorevina do invazivnih malignih tumora. Predstavljaju klinički problem budući da je etiologija tih promjena vrlo raznolika, tijek bolesti često asimptomatski, a potencijalno su malignog karaktera. Tijekom godina broj pacijenata s dijagnosticiranim cističnim lezijama gušterače je značajno porastao prvenstveno zbog napretka radioloških tehnika i starenja populacije. Kompjutorizirana tomografija i magnetska rezonancija predstavljaju izvrsne slojevne slikovne metode za otkrivanje i karakterizaciju cističnih lezija te su predvodnice u dijagnostici i temelj odluke o terapijskom pristupu. U radu ćemo ukratko prikazati spektar najčešćih cističnih lezija gušterače i njihovu radiološku prezentaciju.
Biološka terapija u liječenju kroničnih upalnih bolesti crijeva
Authors: Milaković Dora , Crnčević Urek Marija
Published: June 2020

Upalne bolesti crijeva kronični su upalni poremećaji gastrointestinalnog sustava nepoznatog uzroka u koje ubrajamo Crohnovu bolest, ulcerozni kolitis i nedeterminirani kolitis. Ciljevi liječenja upalnih bolesti crijeva su postizanje i održavanje remisije bolesti, kao i mukozno cijeljenje. Biološka terapija predstavlja značajan napredak u liječenju s obzirom na to da može inhibirati upalnu kaskadu u podlozi kronične upalne bolesti te na taj način modificirati tijek i zaustaviti progresiju bolesti. S obzirom na to da je riječ o kompleksnim terapijama s potencijalno ozbiljnim nuspojavama, njihova primjena zahtijeva iskustvo i provodi se prvenstveno u specijaliziranim centrima, ali sve više u općim i županijskim bolnicama.
Podudarnost procijenjene veličine rezidualnog tumorskog procesa magnetskom rezonancijom i patohistološkom dijagnostikom u pacijentica s karcinomom dojke nakon provedene neoadjuvantne kemoterapije
Authors: Černeka Elvis , Miletić Damir , Avirović Manuela , Grebić Damir , Valković Zujić Petra
Published: June 2020

Cilj. Cilj istraživanja je procijeniti podudarnost veličine rezidualnog tumora, izmjerene magnetskom rezonancijom (MR) i patohistološkom dijagnostikom (PHD) u pacijentica s karcinomom dojke nakon provedene neoadjuvantne kemoterapije (NAK) te procijeniti mogući utjecaj ypT stadija tumora na nepodudarnost veličina izmjerenih navedenim metodama. Ispitanici i metode: U retrospektivno istraživanje uključeno je 50 pacijentica. Uključni kriterij su pacijentice kod kojih je učinjen operativni zahvat uz prethodno proveden NAK karcinoma dojke, na što je odgovor praćen s najmanje dva MR pregleda. Veličina tumora na MR-u uspoređena je s veličinom na PHD-u (zlatni standard) pomoću regresijske analize Passing-Bablok te je izračunat njihov koeficijent korelacije. Analizirana su sva odstupanja i podudarnosti veličine, kao i eventualni utjecaj ypT stadija tumora na razliku između dviju metoda. Razlika od ± 0,5 cm u veličini tumora procijenjenih slikovnom metodom i u PHD nalazu smatrale su se podudarnima veličinama. Rezultati: Srednja vrijednost veličine rezidualnog tumora na MR-u iznosila je 19,1 ± 17,71 mm, dok je na PHD-u iznosila 16,87 ± 18,19 mm. Izračunati r koeficijent korelacije iznosi 0.64 (p < 0.001). Provedenom analizom potvrđeno je da nema značajne razlike izmjerenih veličina tumora na MR-u i PHD-u (p = 0.552) te se metode mogu smatrati podudarnima. Nije uočena statistički značajna razlika u ovisnosti o ypT stadiju tumora koja bi utjecala na nepodudarnost veličina. Zaključci: Među dvjema metodama nema konstantnog niti proporcionalnog odstupanja u mjerenjima te se metode mogu smatrati podudarnim. MR dojke je dobra metoda za procjenu veličine rezidualnog tumora dojke kod pacijentica koje su podvrgnute neoadjuvantnoj kemoterapiji usporedno s PHD-om (zlatni standard).
Učinkovitost liječenja bola terapijom udarnog vala u plantarnom fascitisu, kalcificirajućem tendinitisu ramena i lateralnom epikondilitisu lakta
Authors: Grubić Kezele Tanja , Fužinac-Smojver Ariana , Đudarić Luka , Kauzlarić-Živković Tamara , Nemrava Jan
Published: June 2020

Uvod: Terapija udarnim valom (TUV) (od engl. shockwave therapy) je neinvazivna metoda temeljena na mehaničkim pulsovima koji se u obliku vala šire kroz ljudsko tijelo te izazivaju mikroskopske intersticijalne i ekstracelularne biološke učinke među kojima je i regeneracija tkiva. Cilj: Cilj ovog retrospektivnog istraživanja bio je ispitati učinkovitost i razlike u liječenju bola TUV-om u pacijenata s dijagnozama plantarni fascitis, kalcificirajući tendinitis ramena i lateralni epikondilitis lakta nakon upotrebe tri i pet uzastopnih tretmana. Ispitanici i metode: U radu su korišteni podatci pacijenata iz baze podataka Zavoda za fizikalnu i rehabilitacijsku medicinu Kliničkog bolničkog centra u Rijeci, a pri tome su u skladu s Helsinškom deklaracijom ostali anonimni: dob, spol, mjerenja intenziteta bola dobivena uz pomoć vizualno analogne skale (od engl. Visual Analogue Scale, VAS). Ispitanici su podijeljeni u dvije grupe za svaku dijagnozu (TUV3 i TUV5). Ispitivanje je sadržavalo ukupno 148 pacijenata: plantarni fascitis N = 50, kalcificirajući tendinitis ramena N = 50 i lateralni epikondilitis lakta N = 48. Rezultati: Primjena terapije udarnim valom kod pacijenata s dijagnozama plantarni fascitis, kalcificirajući tendinitis ramena i lateralni epikondilits lakta, s ciljem smanjenja intenziteta bola, pokazala se uspješnom. Dobivenim rezultatima utvrđeno je da primjena pet TUV tretmana dovodi do boljih rezultata smanjenja bola u sve tri dijagnoze negoli samo tri primijenjena tretmana (p < 0,001; p < 0,001; p < 0,001). Nadalje je utvrđeno da se nakon tri primijenjena tretmana postigao bolji učinak smanjenja bola kod plantarnog fascitisa negoli kod kalcificirajućeg tendinitisa ramena i lateralnog epikondilitisa lakta, dok nakon pet primijenjena tretmana nije bilo razlike u smanjenju bola među dijagnozama. Zaključak: Ova studija preporučuje primjenu pet tretmana kod sve tri dijagnoze kako bi pacijenti imali bolji učinak smanjenja bola.
Bifid cardiac apex in Pallister-Killian syndrome
Authors: Barišić Anita , Finderle Aleks , Petrović Oleg , Vraneković Jadranka
Published: June 2020

Aim: Pallister-Killian syndrome (PKS) is a rare chromosomal disorder, caused by tissue-limited mosaicism for an isochromosome 12p. Prenatal diagnosis of PKS is generally incidental. Although clinical presentation of PKS varies, cytogenetic findings are constant, and include a tetrasomy of chromosome 12p. We report a case of prenatally diagnosed PKS with unique dysmorphic feature: bifid cardiac apex, a type of morphology that has not been documented before. Case presentation: Our patient was the 38-year-old pregnant woman who underwent amniocentesis. Cytogenetic analysis of amniotic fluid detected a mosaic karyotype with a supernumerary chromosome (SMC) in 64 % of fetal amniocytes. To determine the chromosomal origin of SMC, fluorescence in situ hybridization was performed and tetrasomy 12p was confirmed: mos 47,XY,+mar[18]/46,XY[10].ishi(12p)(8M16/SP6++,CEP12+,VIJyRM2196-). Ultrasound examination showed a fetus with cleft lip, echogenic focus in the left ventricle of the heart and shortened fetal long bones. After receiving a genetic counseling for PKS, the woman requested a termination of pregnancy. A postmortem inspection of the fetus revealed a complex heart anomaly that includes bifid cardiac apex and ventricular septal defect. Conclusions: This report expands the clinical manifestations of PKS with a unique feature of bifid cardiac apex, and highlights the targeted prenatal diagnosis of PKS if specific ultrasound markers are present.
Online Information Exchange and Anxiety Spread in the Early Stage of the Novel Coronavirus (COVID-19) Outbreak in South Korea: Structural Topic Model and Network Analysis (Preprint)
Authors: Jo Wonkwang , Lee Jaeho , Park Junli , Kim Yeol
Published: June 2020

BACKGROUND

In case of a population-wide infectious disease outbreak, such as the novel coronavirus disease (COVID-19), people’s online activities could significantly affect public concerns and health behaviors due to difficulty in accessing credible information from reliable sources, which in turn causes people to seek necessary information on the web. Therefore, measuring and analyzing online health communication and public sentiment is essential for establishing effective and efficient disease control policies, especially in the early stage of an outbreak.

OBJECTIVE

This study aimed to investigate the trends of online health communication, analyze the focus of people’s anxiety in the early stages of COVID-19, and evaluate the appropriateness of online information.

METHODS

We collected 13,148 questions and 29,040 answers related to COVID-19 from Naver, the most popular Korean web portal (January 20, 2020, to March 2, 2020). Three main methods were used in this study: (1) the structural topic model was used to examine the topics in the online questions; (2) word network analysis was conducted to analyze the focus of people’s anxiety and worry in the questions; and (3) two medical doctors assessed the appropriateness of the answers to the questions, which were primarily related to people’s anxiety.

RESULTS

A total of 50 topics and 6 cohesive topic communities were identified from the questions. Among them, topic community 4 (suspecting COVID-19 infection after developing a particular symptom) accounted for the largest portion of the questions. As the number of confirmed patients increased, the proportion of topics belonging to topic community 4 also increased. Additionally, the prolonged situation led to a slight increase in the proportion of topics related to job issues. People’s anxieties and worries were closely related with physical symptoms and self-protection methods. Although relatively appropriate to suspect physical symptoms, a high proportion of answers related to self-protection methods were assessed as misinformation or advertisements.

CONCLUSIONS

Search activity for online information regarding the COVID-19 outbreak has been active. Many of the online questions were related to people’s anxieties and worries. A considerable portion of corresponding answers had false information or were advertisements. The study results could contribute reference information to various countries that need to monitor public anxiety and provide appropriate information in the early stage of an infectious disease outbreak, including COVID-19. Our research also contributes to developing methods for measuring public opinion and sentiment in an epidemic situation based on natural language data on the internet.
Marrying Medical Domain Knowledge With Deep Learning on Electronic Health Records: A Deep Visual Analytics Approach (Preprint)
Authors: Li Rui , Yin Changchang , Yang Samuel , Qian Buyue , Zhang Ping
Published: June 2020

BACKGROUND

Deep learning models have attracted significant interest from health care researchers during the last few decades. There have been many studies that apply deep learning to medical applications and achieve promising results. However, there are three limitations to the existing models: (1) most clinicians are unable to interpret the results from the existing models, (2) existing models cannot incorporate complicated medical domain knowledge (eg, a disease causes another disease), and (3) most existing models lack visual exploration and interaction. Both the electronic health record (EHR) data set and the deep model results are complex and abstract, which impedes clinicians from exploring and communicating with the model directly.

OBJECTIVE

The objective of this study is to develop an interpretable and accurate risk prediction model as well as an interactive clinical prediction system to support EHR data exploration, knowledge graph demonstration, and model interpretation.

METHODS

A domain-knowledge–guided recurrent neural network (DG-RNN) model is proposed to predict clinical risks. The model takes medical event sequences as input and incorporates medical domain knowledge by attending to a subgraph of the whole medical knowledge graph. A global pooling operation and a fully connected layer are used to output the clinical outcomes. The middle results and the parameters of the fully connected layer are helpful in identifying which medical events cause clinical risks. DG-Viz is also designed to support EHR data exploration, knowledge graph demonstration, and model interpretation.

RESULTS

We conducted both risk prediction experiments and a case study on a real-world data set. A total of 554 patients with heart failure and 1662 control patients without heart failure were selected from the data set. The experimental results show that the proposed DG-RNN outperforms the state-of-the-art approaches by approximately 1.5%. The case study demonstrates how our medical physician collaborator can effectively explore the data and interpret the prediction results using DG-Viz.

CONCLUSIONS

In this study, we present DG-Viz, an interactive clinical prediction system, which brings together the power of deep learning (ie, a DG-RNN–based model) and visual analytics to predict clinical risks and visually interpret the EHR prediction results. Experimental results and a case study on heart failure risk prediction tasks demonstrate the effectiveness and usefulness of the DG-Viz system. This study will pave the way for interactive, interpretable, and accurate clinical risk predictions.
“Smartphone apps are cool, but do they help me?” A thematic analysis of adolescents’ expectations on apps to manage Nonsuicidal Self-injury (Preprint)
Authors: Čuš Anja , Edbrooke-Childs Julian , Ohmann Susanne , Plener Paul L. , Akkaya-Kalayci Türkan
Published: June 2020

BACKGROUND

Nonsuicidal Self-injury (NSSI) is a major mental health problem associated with negative psychosocial outcomes and it most often starts in early adolescence. Although recent technology-enabled interventions show promise in managing NSSI, they rarely consider expectations of their intended target group.

OBJECTIVE

This study explored patients’ experiences, needs and preferences about future digital interventions that are delivered through smartphones.

METHODS

We interviewed fifteen young females aged 12-18 who engaged in NSSI in the past year and were in contact with mental health services. The data was analysed following a thematic analysis approach and the findings were discussed in one follow up interview to include member checking.

RESULTS

This study identified two main themes that represent shared patterns of meaning across the interviews. The first theme Experiences of NSSI depicts the experiences and needs of young people with NSSI. The second theme App in Context portrays preferences of young people about smartphone interventions and includes adolescents’ perspectives on how technology can improve or hinder engaging with these interventions.

CONCLUSIONS

Young people show interest in using smartphone interventions if they recognize them as helpful, relevant for their life situation and easy to use. The authors adopt these study findings to discuss how the future NSSI and mental health interventions could be more engaging through taking into account three contexts in which mental health interventions are embedded (mental health condition, person using the intervention, and technology-related factors). The cooperation between mental health experts, human computer interaction professionals and people with lived experience is vital to advance the development of digital resources for mental health and NSSI management.
Healthcare apps on smartphones available in Brazil: a preliminary classification (Preprint)
Authors: Pereira Neto André De Faria , Barbosa Leticia , Paolucci Rodolfo
Published: June 2020

UNSTRUCTURED

Billions of people in the world own a smartphone. It is a low-cost, portable computing device with countless features, among which applications stand out, which are programs or software developed to meet a specific goal. A wide range of applications available ranging from entertainment and personal organization to work and education is available currently. It is a vast and profitable market. Health applications have been a means of intervention for different areas, including chronic diseases, epidemics, and health emergencies. A recently published paper in the journal with the highest impact factor in Digital Health (“Journal of Medical Internet Research”) proposes a classification of health applications. This study performs a critical analysis of this organization and presents other sort criteria. This paper also presents and analyzes the “Meu Info Saúde” (“My Health Info”) app – a pioneering government initiative focused on primary care launched by the Oswaldo Cruz Foundation. The application classification proposal that will be presented builds on the intervention strategies in the health-disease process, namely: “Health Promotion”, “Disease Prevention” and “Care, Treatment and Rehabilitation”, as defined by official documents such as the World Health Organization and the Centers for Disease Control and Prevention. Most applications present in the sample are of private and foreign origin, free to download, but with a display of ads or the sale of products and services. The sampled applications were classified as “Health Promotion”, and some applications have also been categorized as “Disease Prevention” or “Care, Treatment or Rehabilitation” because they have multiple functionalities. The applications identified as “Health Promotion” focused only on individuals’ lifestyle and their increased autonomy and self-care management capacity. From this perspective, the apps analyzed in this paper differ from the “Meu Info-Saúde” application developed at Fiocruz.
Connected Mental Health Solutions to Assist Healthcare Workers with their Mental Health during COVID-19: A Literature Review (Preprint)
Authors: Drissi Nidal , Ouhbi Sofia , Ghogho Mounir , Janati Idrissi Mohammed Abdou
Published: June 2020

BACKGROUND

Covid-19, a highly infectious disease that spread to all regions of the world, has influenced the education, economy, and all daily life activities, and caused global feelings of stress, fear, and depression. But most importantly it influenced health care systems and health care workers (HCWs). HCWs are working under hard circumstances and are suffering from different psychological stressors, in addition to several ethical and moral dilemmas. HCWs were found to suffer from different psychological issues caused by the pandemic, including, stress, anxiety, and depression, and they are undeniably in need of mental care interventions.

OBJECTIVE

The aim of this study is to identify connected mental care intervention (i.e. technology-based interventions), developed for HCWs during the COVID-19 pandemic, that are reported in the literature.

METHODS

A review, following the PRISMA protocol, of the existing literature was conducted, by searching the sources: IEEE Digital Library, ACM Digital Library, ScienceDirect, Scopus, and PubMed.

RESULTS

A total of 11 publications were included in the final selection. Several interventions were extracted from the publications and presented in this study.

CONCLUSIONS

COVID-19 has a huge impact on the mental health of HCWs, to the extent of leading to multiple suicide cases. In these tough times, HCWs are in need for mental care interventions. Under the circumstances caused by COVID-19, connected mental health interventions including online platforms, programs, and mobile apps, seem to be suitable and effective tools to deliver the needed care to HCWs. These solutions help provide care remotely, respecting the recommended safety measures, which include social distancing, and avoiding in-person contact.
Efek integrated nutrition programme terhadap profil lipid dan komposisi tubuh pada remaja obes
Authors: Ardiaria Martha , Kustanti Erin Ratna , Sulistiani Ria Purnawian , Noer Etika Ratna
Published: June 2020

The effect of integrated nutrition programme on lipid profile and body composition among adolescent obesityBackground: Obesity is a serious public health issue increasingly in the adolescent. Obesity in adolescence will continue into adulthood and lead to later health problems. The adolescent has high food dense calories which high fat and low in fiber that can trigger obesity. Integrated Nutrition Programme (INP) is an intervention model for obesity with an emphasis on a low-calorie diet, low fat, high fiber, moderate physical activity, and nutrition counseling.Objective: This study aimed to evaluate the effect of INP on lipid profile and body composition in obese adolescents.Methods: Quasi-experimental study pre-post trial design with a total of subjects 18 obese adolescents. Duration of intervention in subjects for four weeks with a hypocaloric diet, low fat, high fiber, and prepared by a dietician. Moderate exercise and dietary counseling were conducted on the subject regularly. Bodyweight (BW) and waist circumference (WC) were monitored once a week. Food record intake is done before and during the intervention.Results: The mean weight loss of 1.55 kg. There is a difference in mean BW, WC, and BMI (p<0.01), whereas there were no significant differences in lipid profiles and body composition between before and after the intervention.Conclusions: INP can significantly affect weight loss, BMI, and WC as well as a significant increase in physical activity.
Lingkar pinggang dan lingkar leher dengan kadar kolesterol total pada wanita usia subur obesitas
Authors: Manik Rifial Ramadhan , Widyastuti Nurmasari , Nissa Choirun
Published: June 2020

Waist circumference, and neck circumference correlated to total cholesterol among reproductive-age women with obesityBackground: Dyslipidemia is a metabolic disorder condition that is closely related to cholesterol and obesity. The prevalence of obesity in reproductive-age women (>18 years) in Indonesia increased dramatically. Reproductive age women with obesity are at greater risk of hypercholesterolemia compared with non-obese. Waist circumference (WC), mid-upper arm circumference (MUAC), and neck circumference (NC) can be used as a marker of higher or low cholesterol levels. Objective: This study aimed to determine the relationship between WC, MUAC, and NC with total cholesterol. Methods: The study design was cross-sectional with several subjects were 54 women of reproductive-aged 18-29 years. Subject with obese category (BMI ≥25kg/m2) was measured the WC, MUA, and NC as an independent variable and total cholesterol as the dependent variable, and dietary intake (total fat, cholesterol, and saturated fat) as confounding variables. The bivariate analysis used the Pearson correlation test. Multivariate analysis used multivariate linear regression. Results: Bivariate analysis showed there was a significant relationship between WC and NC to total cholesterol (p=0.006 and p=0.001), but not on MUAC (p=0.063). In multivariate analysis, NC is the most significantly related to total cholesterol (β=0.367; p=0.004; Adjusted R Square 24%) than WC. Conclusions: There is a significant relationship between WC and NC to the total cholesterol in women of reproductive age obesity. NC more significantly related to total cholesterol.
IMPACT OF PHARMACIST LED INTERVENTION IN IMPROVING MEDICATION KNOWLEDGE AMONG CHRONIC KIDNEY DISEASE PATIENTS: A PRELIMINARY STUDY
Authors: PANEERSELVAM GANESH SRITHERAN
Published: June 2020

Objective: This study aims to evaluate the impact of pharmacist-led medication management clinics in improving medication knowledge among chronic kidney disease (CKD) patients.

Methods: This was a retrospective study using a convenient sampling method. All CKD patients age 18 y above with complete pre and post knowledge assessment record were included. The pre-knowledge assessment was done at baseline while the post-assessment was done after a few sessions of medication knowledge teaching done by the clinical pharmacist using medication knowledge assessment form. Demographics data and pre-post knowledge scores were retrieved from patient’s electronic medical record system. All data were analysed using the Statistical Package for Social Sciences (SPSS) version 24.

Results: The study shows a total of 13 patients, with the majority being Malay, male with a median age of 60. 84.6% of the patients were consuming more than 5 medications. While 53.9% of patients fall into CKD stage 4 and 5. Patient’s knowledge towards medications improved significantly with an increase in the median pre-knowledge score of 13 to post knowledge score of 18 (p<0.05) after completion of the session.

Conclusion: From this preliminary evaluation, pharmacist-led medication management clinic resulted in significant improvement of medication knowledge which is further expected to improve medication adherence and delay the disease progression
ARTABOTRYS HEXAPETALUS (L. F.) BHANDARI: A PLANT WITH ENORMOUS BIOMEDICAL POTENTIAL
Authors: PURI ABHIJEET V.
Published: June 2020

This review is intended to investigate the published report regarding phytochemical, ethnomedicinal, and pharmacological activities and put forth the therapeutic potential of Artabotrys hexapetalus (L. f.) Bhandari. (A. hexapetalus). It belongs to the family Annonaceae, one of the therapeutically important plants, broadly distributed throughout the world. An extensive review of the literature available in various recognized databases including logical writing and scientific literature, search engines such as Springerlink, ScienceDirect, SciFinder, PubMed, Scopus, Google Scholar, and BioMed Central as well as relevant books, websites, scientific publications, and dissertations were utilized as a source of information that provided an up-to-date review. Phytochemical profiling of these species revealed the presence of some imperative phytochemicals alkaloids, terpenoids, anthraquinones, butyrolactones, flavonoids, neolignans, phenolic compounds, and leucoanthocyanins as the basis of its valuable therapeutic properties. The other imperative phytoconstituents which contribute to the therapeutic properties are isoamericanin A, isoamericanol, americanin, artabotricinol and artabotriol, β-unsaturated-β-butyrolactones, arapetaloside taxifolin, apigenin-7-O-apiosylglucoside, glucoluteolin, and artabotrine. The pharmacological activities exhibited by Artabotrys hexapetalus as antimicrobial, antileishmanial, antioxidant, antifungal, antifertility, and anthelmintic properties are attributed to the presence of valuable bioactive phytoconstituents. Considering these facts an effort was made to present a comprehensive review enlightening the taxonomical, phytochemical, and pharmacological activities of plant Artabotrys hexapetalus. Future research can be directed to an extensive investigation about phytochemistry, clinical trials, pharmacokinetics, and acquiring safety data to add new dimensions to the therapeutic utilization of Artabotrys hexapetalus and other Artabotrys species.
Calidad seminal de ovinos de pelo suplementados con Moringa oleifera (Moringaceae) y Trichanthera gigantea (Acanthaceae)
Authors: Ramírez-Bautista Marco A. , Ramón-Ugalde Julio P. , Aguilar-Urquizo Edgar , Cetzal-Ix William , Sanginés-García Roberto , Domínguez-Rebolledo Álvaro E. , Piñeiro-Vázquez Ángel T.
Published: June 2020

Se evalúo el efecto de la inclusión de Moringa oleifera Lam. y Trichanthera gigantea (Bonpl.) Nees en la dieta de ovinos de pelo (Pelibuey) sobre su calidad seminal. Durante 90 días, se dividieron las dietas de 15 ovinos (24 kg ± 3.95) en tres tratamientos: T1: dieta integral con 30% de M. oleifera + pasto Taiwán (Pennisetum purpureum Schumach.), T2: dieta integral con 30% de T. gigantea + pasto Taiwán y T3: alimento comercial + pasto Taiwán. Se determinaron la ganancia diaria de peso (GDP), rendimiento de la canal (RC), desarrollo testicular (DT) (determinado por el ancho (AE) y la circunferencia escrotal (CE)), el volumen del eyaculado, concentración y motilidad, viabilidad (SYBR-14/IP), actividad mitocondrial (J-C1) e integridad acrosomal (FITC-PSA) en los espermatozoides. No se encontraron diferencias (p>0.05) en la GDP y RC. Se encontraron diferencias (p˂0.05) en el DT, los T1 (AE = 48.84±5.99 mm, CE = 26.48±1.13 cm) y T3 (AE = 48.83±4.34 mm, CE = 26.62±1.27 cm) presentaron valores más elevados que T2 (AE = 44.57±5.59 mm, CE = 25.42±1.50 cm); en la viabilidad, T2 (62.90±6.10%) y T1 (54.00±6.61%) poseen mayores porcentajes que T3 (24.45±7.56%); en la motilidad, T1 (93.9± 2.1%) y T2 (88.6±1.9%) tuvieron mayor porcentaje que T3 (71.9± 4.0%). La inclusión de M. oleifera y T. gigantea en la dieta permite obtener una GDP, RC y DT similar al alimento comercial e incrementa más del 20% de las células espermáticas viables; también mejora algunos parámetros de motilidad, lo que incrementa el potencial reproductivo de los sementales.
Bolos intrarruminales con liberación controlada de minerales traza. Revisión
Authors: León-Cruz Misael , Ramirez-Bibriesca Efrén , López-Arellano Raquel , Miranda-Jiménez Leonor , Rodriguez-Patiño Gabriela , Diaz-Sánchez Victor M. , Revilla-Vázquez Alma L.
Published: June 2020

Los minerales traza son nutrientes esenciales para el mantenimiento de la vida, el crecimiento y la reproducción. Las deficiencias de minerales en rumiantes afectan las funciones fisiológicas y metabólicas que con frecuencia causan enfermedades. El diseño y uso de los bolos intrarruminales de liberación controlada (BILC) es una alternativa para corregir la falta de los microelementos en el organismo. El propósito de esta revisión es evidenciar la información disponible sobre los diferentes tipos de BILC de minerales traza, así como de los métodos de fabricación que incluye: técnicas de extrusión en caliente, granulación por fusión y fusión directa. Además, se describen los efectos de BILC relacionados en la salud, en los parámetros productivos y reproductivos en rumiantes.
Avaliação pelos pares com o uso de tecnologias digitais no ensino superior
Authors: Hypolito Vera Adriana Huang Azevedo , Santos Rosa Selma , Luccas Simone
Published: June 2020

Este artigo apresenta uma Revisão de Literatura a fim de compreender a Avaliação pelos Pares com o uso de tecnologias digitais no Ensino Superior. Identificou-se tecnologias já existentes utilizadas nesse tipo de avaliação; softwares para esse fim e que as estratégias de Online Peer Assessment (OPA) têm sido utilizadas em cursos de formação docente. Os métodos de avaliação da OPA evidenciam competências como a organização e distribuição de pares e o anonimato. Pondera-se que o tema tem ganhado força e que há fragilidades, desafios e contribuições. Um dos desafios é o suporte docente no desenvolvimento do processo e o anonimato da avaliação. Segundo os autores analisados, esta estratégia potencializa a autonomia, a colaboração e autorregulação dos alunos, corroborando como uma “avaliação para a aprendizagem”. Pondera-se que a OPA seja um recurso avaliativo que contribui para reflexão e sistematização da aprendizagem do aluno, agregando valores ao repertório docente.Palavras-chave: Avaliação pelos Pares Online. Tecnologia. Avaliação para a Aprendizagem. Avaliação formativa.
A configurational approach to the determinants of women on boards
Authors: Guedes Maria João , Monteiro Alice Galamba
Published: June 2020

This study applies a qualitative comparative analysis (fsQCA) to test how configurations of gender equality, masculinity, highly educated women, and happiness, alone or in different combinations, explain the presence or absence of women on the board of directors (WoB). The global solution has considerable explanatory coverage and presents four alternative combinations conducive to both the presence and absence of WoB. Overall, the results show that the absence of gender equality is almost a necessary condition for the absence of WoB. The other conditions, per se, are not enough to explain the presence or absence of WoB, but in different combinations they are. For example, the combination of highly educated women, gender equality, and happiness is the solution with a higher consistent value to explain the presence of WoB. In this study, we sought to contribute with a novel, and far-reaching way of considering the determinants of the presence of WoB, moving past the typical determinants of WoB such as board size and board independence, or board members characteristics (such as experience or age) and shifting the focus solely from the corporate context to broader social, cultural and political contexts. The study presents recommendations for academics, practitioners, and policymakers, particularly to consider different determinants of underrepresentation of WoB and how new initiatives shall be implemented to advance the field and transition to economies and societies with greater social justice and gender equality.
REAL TIME CONTROL OF TWIN ROTOR MIMO SYSTEM WITH PID AND FRACTIONAL ORDER PID CONTROLLER
Authors: DOĞRUER Tufan , TAN Nusret
Published: June 2020

This paper presents real-time control applications for the TRMS system. The twin rotor helicopter model has some complex features which make it difficult to control and therefore it can be used an ideal test setup for control applications. In this study, firstly, twin rotor helicopter model is run in real time and mathematical models are determined. According to the mathematical models, fractional order PID controller designs are realized by using Genetic Algorithm and real time pitch and yaw position control of the twin rotor helicopter model is provided. In the optimization algorithm, fractional order PID controller parameters were determined according to four different integral performance criteria. In real-time control of TRMS, integral performance criteria are compared with each other and the results are presented in figures. The results show that the real-time control of the system has been successfully performed using fractional order PID controller.