bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights into The Function and Regulation of Jumonji C Lysine Demethylases as Hypoxic Responsive Enzymes
Authors: Chopra Anand , Adhikary Hemanta , Willmore William G. , Biggar Kyle K.
Published: December 2019

Cellular responses to hypoxia (low oxygen) are governed by oxygen sensitive signaling
pathways. Such pathways, in part, are controlled by enzymes with oxygen-dependent catalytic activity,
of which the role of prolyl 4-hydroxylases has been widely reviewed. These enzymes inhibit hypoxic
response by inducing the oxygen-dependent degradation of hypoxia-inducible factor 1α, the master
regulator of the transcriptional hypoxic response. Jumonji C domain-containing lysine demethylases
are similar enzymes which share the same oxygen-dependent catalytic mechanism as prolyl 4-
hydroxylases. Traditionally, the role of lysine demethylases has been studied in relation to demethylation
activity against histone substrates, however, within the past decade an increasing number of nonhistone
protein targets have been revealed, some of which have a key role in survival in the hypoxic
tumor microenvironment. Within this review, we highlight the involvement of methyllysine in the
hypoxic response with a focus on the HIF signaling pathway, the regulation of demethylase activity by
oxygen, and provide insights into notable areas of future hypoxic demethylase research.
Paracrine Interactions Involved in Human Induced Pluripotent Stem Cells Differentiation into Chondrocytes
Authors: Zhao Yunchang , Liu Honghao , Zhao Chunjie , Dang Peng , Li Haijian , Farzaneh Maryam
Published: December 2019

Osteoarthritis (OA), as a degenerative joint disease, is the most common form of joint disorder
that causes pain, stiffness, and other symptoms associated with OA. Various genetic, biomechanical,
and environmental factors have a relevant role in the development of OA. To date, extensive efforts
are currently being made to overcome the poor self-healing capacity of articular cartilage. Despite the
pivotal role of chondrocytes, their proliferation and repair capacity after tissue injury are limited.
Therefore, the development of new strategies to overcome these constraints is urgently needed. Recent
advances in regenerative medicine suggest that pluripotent stem cells are promising stem cell sources
for cartilage repair. Pluripotent stem cells are undifferentiated cells that have the capacity to differentiate
into different types of cells and can self-renew indefinitely. In the past few decades, numerous attempts
have been made to regenerate articular cartilage by using induced pluripotent stem cells
(iPSCs). The potential applications of patient-specific iPSCs hold great promise for regenerative medicine
and OA treatment. However, there are different culture conditions for the preparation and characterization
of human iPSCs-derived chondrocytes (hiChondrocytes). Recent biochemical analyses reported
that several paracrine factors such as TGFb, BMPs, WNT, Ihh, and Runx have been shown to be
involved in cartilage cell proliferation and differentiation from human iPSCs. In this review, we summarize
and discuss the paracrine interactions involved in human iPSCs differentiation into chondrocytes
in different cell culture media.
Research Situation Analysis of On-line Detection Technology for Power Transformer Winding Deformation
Authors: Li Zhenhua , Jiang Weihui , Qiu Li , Li Zhenxing , Xu Yanchun
Published: December 2019

Background:

Winding deformation is one of the most common faults in power transformers,
which seriously threatens the safe operation of transformers. In order to discover the hidden
trouble of transformer in time, it is of great significance to actively carry out the research of
transformer winding deformation detection technology.

Methods:

In this paper, several methods of winding deformation detection with on-line detection
prospects are summarized. The principles and characteristics of each method are analyzed, and the
advantages and disadvantages of each method as well as the future research directions are expounded.
Finally, aiming at the existing problems, the development direction of detection method
for winding deformation in the future is prospected.

Results:

The on-line frequency response analysis method is still immature, and the vibration detection
method is still in the theoretical research stage.

Conclusion:

The ΔV − I1 locus method provides a new direction for on-line detection of transformer
winding deformation faults, which has certain application prospects and practical engineering
value.
Potassium fertilization in bareroot nurseries in the southern US: a review
Authors: South David B.
Published: December 2019

This review covers most of the published literature on potassium (K) fertilization in bareroot seedbeds with the intent to concentrate on the southern United States. The timing and rates of K fertilization for bareroot seedlings are often based on logic and myths and, as a result, K recommendations vary considerably. Some recommend bareroot pine seedlings be fertilized with twice as much K as nitrogen (N) while others apply less than 100 kg ha-1. It was determined that several long-held claims about K fertilization are invalid. Nursery seedbeds do not need to contain four times as much available K as N and the belief that extra K fertilization will increase freeze tolerance or drought resistance of non-deficient seedlings is invalid. There are no data to support the claim that K fertilization increases root growth or assists in the formation of terminal buds. For sandy seedbeds, there is no need to apply K before sowing. Adding extra K during the fall does not increase seedling morphology or seedling performance when loblolly pine seedlings, at lifting, have more than 0.5% K in needles. A reduction of K fertilization can be achieved by reviewing foliar tests prior to K top-dressings.
“lugares de memória” midiáticos e a preservação da imagem do herói político na imprensa:
Authors: Pádua Gesner Duarte
Published: December 2019

Este artigo aborda como a imagem de herói e mártir da democracia, atribuída ao ex-presidente Tancredo Neves pela mídia na década de 1980, permanece viva na memória coletiva nacional graças, em grande medida, a sua reprodução nos veículos de imprensa eletrônicos, tomados aqui como novos “lugares de memória”, segundo a perspectiva de Pierre Nora e Jacques Le Goff. O corpus empírico é composto por 33 publicações do Portal UOL, revista Veja online e Folha de São Paulo online. Observa-se como recorte temporal a efeméride do aniversário de 30 anos de sua eleição para a Presidência e sua trágica morte, pouco depois. Verifica-se que, a despeito de um lapso temporal de três décadas, a figura do herói político sobrevive na atualidade reelaborada em “lugares de memória” midiáticos que contribuem para a disseminação de certas versões do passado no imaginário coletivo, em operações de enquadramento da memória.
Temporal Expression Classification and Normalization From Chinese Narrative Clinical Texts: Pattern Learning Approach (Preprint)
Authors: Pan Xiaoyi , Chen Boyu , Weng Heng , Gong Yongyi , Qu Yingying
Published: December 2019

BACKGROUND

Temporal information frequently exists in the representation of the disease progress, prescription, medication, surgery progress, or discharge summary in narrative clinical text. The accurate extraction and normalization of temporal expressions can positively boost the analysis and understanding of narrative clinical texts to promote clinical research and practice.

OBJECTIVE

The goal of the study was to propose a novel approach for extracting and normalizing temporal expressions from Chinese narrative clinical text.

METHODS

TNorm, a rule-based and pattern learning-based approach, has been developed for automatic temporal expression extraction and normalization from unstructured Chinese clinical text data. TNorm consists of three stages: extraction, classification, and normalization. It applies a set of heuristic rules and automatically generated patterns for temporal expression identification and extraction of clinical texts. Then, it collects the features of extracted temporal expressions for temporal type prediction and classification by using machine learning algorithms. Finally, the features are combined with the rule-based and a pattern learning-based approach to normalize the extracted temporal expressions.

RESULTS

The evaluation dataset is a set of narrative clinical texts in Chinese containing 1459 discharge summaries of a domestic Grade A Class 3 hospital. The results show that TNorm, combined with temporal expressions extraction and temporal types prediction, achieves a precision of 0.8491, a recall of 0.8328, and a F1 score of 0.8409 in temporal expressions normalization.

CONCLUSIONS

This study illustrates an automatic approach, TNorm, that extracts and normalizes temporal expression from Chinese narrative clinical texts. TNorm was evaluated on the basis of discharge summary data, and results demonstrate its effectiveness on temporal expression normalization.
Turizmde Yeni Ürün Geliştirme ve Pazarlama Stratejileri: Kastamonu Şehir Merkezi Destinasyonu Örneği
Authors: BÜYÜKMEHMETOĞLU Nagehan , OKTAY Kutay
Published: December 2019

Amaç: Turizmden sağlanan gelirlerin
kalkınmaya önemli katkılarının olduğu bilinmektedir. Bu katkılarından dolayı turistik
destinasyonlar arasındaki rekabet hızla artmaktadır. Günümüzde, özellikle küçük
ölçekli destinasyonların, kendini geliştirmiş ve önemli bir yere sahip olan
destinasyonlara karşı rekabette üstün duruma gelecek pazarlama stratejileri
geliştirmeleri gerekli olmaktadır.

Bu
çalışmanın amacı, Kastamonu şehir merkezi destinasyonunda yeni ürün geliştirme
ve pazarlama stratejilerinin neler olması gerektiğinin araştırıl-masıdır

Yöntem: Bu amaçla nitel araştırma yöntemi olan
görüşme tekniğinden yararlanılmıştır. Kastamonu Üniversitesi Turizm Fakültesi
tarafından 23-25 Kasım 2017 tarihleri arasında gerçekleştirilen I. Uluslararası
Sürdürülebilir Turizm Kongresi’ne katılan 20 akademisyen ile görüşme yapılarak
veriler toplanmış ve içerik analizi tekniği ile
çözümlenmiştir.

Bulgular: Araştırmada, Kastamonu Şehir
Merkezinin tarih, kültür, inanç ve eko turizm destinasyonu olarak ele alınması
gerektiği, konumlandırmanın da bu doğrultuda yapılabileceği, turizm açısından
yeterli potansiyele sahip olduğu, turizmin reklam ve tanıtımlarla desteklenmesi
gerektiği, paydaşlarla iletişimin arttırılması ve mevcut ürünlerin tanıtılarak/
geliştirerek yöresel ürünler ekseninde hareket edilmesi gerektiği bulgularına
ulaşılmıştır.

Sonuç: Kastamonu, kültürü, sanatı, el
işçiliği, yöresel yemekleri ve ürünleri bakımından oldukça zengin olmasından
dolayı yeni turistik ürünlerin de bunlar üzerinden geliştirilmesi ve var olan
mevcut ürünlerde de bu doğrultuda farklılaşmaya gidilmesi gerektiği sonucu
ortaya çıkmıştır.
Homology Modeling and Structural Dynamics of the Glucose Oxidase
Authors: Maulana Farhan Azhwin , Ambarsari Laksmi , Wahyudi Setyanto Tri
Published: December 2019

Glucose oxidase from Aspergillus niger IPBCC.08.610 (GOD_IPBCC) is a locally sourced flavoenzyme from Indonesia that can potentially be developed in a variety of industrial processes. Although this enzyme has a high activity in catalyzing the redox reactions, the use of this enzyme was still limited to be applied as glucose biosensor. Using information from the amino acid sequences, a computational structure of GOD_IPBCC was therefore designed by homology modeling method using two homologous structures of GOD from protein data bank (1CF3 and 5NIT) as the templates. The quality of the resulting structures was evaluated geometrically for selection of the best model, and subsequently, 50 ns of MD simulations were carried out for the selected model as well as the corresponding template. Results obtained from the validation analysis showed that the 1CF3 template-built structure was selected as the best reliable model. The structural comparison exhibited that the best-modeled structure consisted of two functional domains and three catalytic residues similarly to the corresponding experimental structure. The overall dynamic behavior of the 50 ns of the structure was structurally stable and comparable with that of the positive control both from globally and locally observations. Implications of these stable nature within the best-modeled structure unfold the possibilities in search of notable residues and their roles to enhance enzyme thermostability.
Multivariate Statistical Analysis Applied to Water Quality of a Tropical Coastal Lagoon, Cartagena, Colombian Caribbean
Authors: Baldiris-Navarro Ildefonso , Acosta-Jimenez Juan Carlos , Gonzalez-Delgado Angel Dario , Realpe-Jimenez Alvaro , Fajardo-Cuadro Juan Gabriel
Published: December 2019

Coastal lagoons are one of the most threatened ecosystems in the world, because of population growth, habitat destruction, pollution, wastewater, overexploitation and invasive species which are the main causes of their degradation. The objective of this paper was to evaluate the water quality behavior in a stressed coastal lagoon in Cartagena, Colombian Caribbean. Environmental data was analyzed using hypothesis testing, confidence intervals, and also Principal components analysis (PCA). The study was focused on water parameters such as dissolved oxygen (DO), biochemical oxygen demand (BOD5), chemical oxygen demand (COD), salinity, pH, total dissolved solids, total coliforms (TC), Fecal coliforms (FC), ammonium (NH4+) and total phosphorus (TP). The analysis was conducted in line with the Colombian national water standard. Results showed that BOD5, COD, phosphorus, and coliforms are out of the limits for these variables in Colombia and are reaching levels that may be a threat to human health. Principal components analysis detected five components that explained 79.4% of the variance of data and showed that anthropogenic and temporal factors might be affecting the variation of the parameters.
Ekspansi Query Berbasis Semantik Pada Online Public Access Catalog (OPAC)
Authors: Dirga Nugraha Nirindra Primavera , S.Kom, M.Kom. Maskur , Hayatin Nur
Published: December 2019

Digital library is an important system useful as the fulfillment of information needs library collection. The Online Public Access Catalog (OPAC) is a feature available in digital libraries that lets you browse library collections. In this research, semantic based query expansion system is developed. The goal is to improve search results to be more relevant. Domain used is information technology where book data obtained from online book site and book publishing sites as much as 500 data. The stage is to build ontology according to the data obtained. The formation of ontology refers to the data of UMM Informatics Engineering curriculum which refers to the Association for Computing Machinery (ACM) Ontology is applied to find the connection between a user entered keyword. To support the search results used cosine similarity method. Cosine similarity is a method to calculate the similarity between search results with user keywords so as to generate search results ranking. Stages of testing the system using precision obtained a value of 65.6. This indicates that the system is capable enough to provide search results that are relevant to a user's search keyword.
Kariyer Değerlerinin Tükenmişlik Düzeyi Üzerindeki Etkisi: Hopa İlçesinde Öğretmenler Üzerinde Bir Uygulama
Authors: DOĞAN Özgür , DURSUN Muhammed Kürşad
Published: December 2019

Tükenmişlik sendromu günümüz iş dünyasının önemli bir sorunudur. Tükenmişliği doğuran birçok içsel ve dışsal neden vardır. Bireylerin, mesleki değerleriyle uyumlu bir mesleği seçmemeleri ise tükenmişliği doğuran ya da düzeyini arttıran önemli bir içsel faktördür. Bu çalışmanın temel amacı, öğretmenlerin kariyer değerlerinin, tükenmişlik düzeyleri üzerindeki etkisini incelemektir. Bu bağlamda, kariyer değerleri ve tükenmişlik konularıyla ile ilgili literatür incelenmiştir. Aralarındaki ilişki, Hopa ilçesinde görev yapan öğretmenlerin oluşturduğu 154 kişilik bir örneklem üzerinde araştırılmıştır. Sonuç olarak, güvenlik değerinin duygusal tükenme ile pozitif yönlü, yaşam tarzı değerinin ise negatif yönlü bir ilişkiye sahip olduğu bulgusuna ulaşılmıştır. Yaşam tarzı değerinin ise azalan kişisel başarı boyutuyla negatif yönlü bir ilişkiye sahip olduğu bulgusuna ulaşılmıştır. Yapılan regresyon analizi; güvenlik ve yaşam tarzı değerlenin, bazı tükenmişlik boyutları üzerinde etkileme gücüne sahip olduğunu göstermiştir.
Smallholders Oil Palm: Problems and Solutions
Authors: Sokoastri Valentina , Setiadi Doni , Hakim Arif Rakhman , Mawardhi Andre Dani , Fadli M Lukman
Published: December 2019

Forty percent of the total oil palm plantation area in Indonesia belong to the smallholder palm oil plantations. The productivity of smallholder oil palm plantations is still relatively low, only around 2-3 tons of CPO/ha/year under PBN dan PBS. The aim of this study is to identify internal dan external constraints that cause low productivity of smallholder oil palm dan the recommended solutions. This research was taken in Sanggau dan Sintang Regencies which are the largest areas of smallholder palm oil plantation in West Borneo. Data obtained were analyzed by SWOT. The results showed that there were four main strategies to increase productivity dan solve problems on oil palm plantation in Sanggau dan Sintang Regencies, namely, 1) intensifying technical training of oil palm cultivation to increase the farmers’ knowledge dan capabilities, 2) increasing the role dan ability of farmer institutions both farmer groups dan ‘koperasi’ in establishing cooperation with stakeholders dan in marketing fresh fruit bunch (FFB), 3) escalating the awareness dan understanding of farmers in using digital information technology to support their business activities on oil palm, dan 4) strengthening the government protection against middlemen.
Ways of Visiting: non-traditional and peripheral approaches to museums
Authors: Bruno Moreschi
Published: December 2019

This exposition is part of my PhD thesis that discusses the possibilities of building approaches in museological institutions, based on specific case studies that were visited and problematized during the study. The result is an experimental inventory of possibilities for critical action in these legitimating spaces of art and history - with an interest in the decoding of their discourses and strategies, revealing their power games, explicit or implicit, and often moving in the opposite direction to their procedures.
Just a mere Spring to take: Embedding in Capitalocenic Atmospheres
Authors: Christoph Solstreif-Pirker
Published: December 2019

30 years after the publication of Félix Guattari’s “The Three Ecologies,” we are facing a turning point in the way we are encountering our environment. Established concepts of “nature” have proved to be considerably part of a grand homocentric design whose spatiality Peter Sloterdijk poignantly defined as the “World Interior of Capital.” To investigate these capitalocenic strata, it becomes necessary to re-territorialize institutionalized debates, conceptions and practices, and perceive contemporary landscapes as manifold, unknown and peripheral alterities.

This research exposition aims to encounter the capitalocenic field, its actors and inherent specificities, and to propose a peripheral methodology for its investigation. According to its etymological roots, periphery not only implies a field or site at “the outer surface”, but also refers to the Greek verb periphérō, meaning “to carry around.” This adds a proto-ethical component, as we become part of a carrying and compassionate interplay with virtual forces of capitalocenic dominance, violence, and destruction.

In this intimate moment of becoming peripheral, we are striving from the grand institutional narrative towards the fragility of an uncertain world interior. To Félix Guattari, this is an act of empathy, of an affective affinity and imaginary re-construction that unfolds new practices, grounds, and epistemologies of how to encounter our manmade planet. Furthermore, it highlights the importance of peripheral discourse on the edge of the planetary crisis, and unfolds a vibrant and democratic borderspace within the all-encompassing ecological trauma.

Departing from Victor Turner’s “social drama” and the unpredictability of a global monetary system, the research exposition focuses on the specific context of Iceland as a knot geographically located within the global fabric of the Capitalocene. Being the site of a massive banking crisis between 2008 and 2011, the island-state is seen as an artificial environment of capitalist warfare, based on an ecosystem of virtual forces that actualize themselves on a social, economic, cultural or ecological level.

Applying a situated performative research praxis, the research exposition affirmatively investigates this manifold and monetary-driven spatiality. As the research exposition suggests, performative research allows to confront the unpredictability of the capitalocenic field in all its complexity and to pave the way for “vanquishing [...] or even befriending“ the dominant forms of global financial market capitalism” (Gilles Deleuze, Logic of Sensation). “Just a mere Spring to take” is a discursive assemblage of various investigative highlights on a virtual, global and elusive phenomenon, aiming at peripherically unfolding horizons of performative thinking, and enabling a fragile intra-active confrontation with our vertiginous, traumatized but still living cosmos.
Dagerotipija u Zagrebu (1839. – 1855.)
Authors: Gržina Hrvoje
Published: December 2019

Članak rekapitulira postojeće i donosi brojne nove
podatke o dagerotipijskoj djelatnosti u Zagrebu sredinom devetnaestoga stoljeća.
Slijedom napisa objavljenih u onodobnim novinama rekonstruira se ozračje
dolaska novoga izuma u Zagreb 1839. godine kao i razina spoznaje o ovome ranome
fotografskom procesu u hrvatskome društvu. Posebna je pozornost poklonjena
Demetru Novakoviću, prvomu hrvatskom dagerotipistu koji je, po svemu sudeći,
poduku za izradu dagerotipija dobio izravno u Parizu u vrijeme javne
demonstracije procesa. Rad ostalih praktičara – uglavnom putujućih
dagerotipista – koji su djelovali u glavnome hrvatskom gradu ocrtan je na
temelju podataka dostupnih kroz novinske oglase i nešto literature. Među njima valja
istaknuti Johanna Boscha, predstavnika takozvane Bečke škole dagerotipije te
Ferdinanda Rahmanna i Josepha Kallaina, čije rivalstvo i nadmetanje u kvaliteti
izrade dagerotipija predstavlja prvi zabilježeni primjer fotografske
konkurencije na hrvatskome prostoru.
Study of heat and mass transfer control inside channel partially filled with a porous medium using nanofluids
Authors: Ben Hamida , Massoudi Mohamed , Marzouki Riadh , Kolsi Lioua , Almeshaal Mohammed , Hussein Ahmed
Published: December 2019

The steady mixed convection of heat and mass transfer inside and outside a
porous vertical wall is numerically studied. The porous wall, placed in a
vertical channel, contains a solid phase, a nanofluid phase (Water-Al2O3 or
Water-Cu) and gas phase. The effect of several physical quantities such as
nanoparticle volume fraction, ambient temperature and initial nanofluid
saturation on heat and mass transfer were investigated. Results reveal that
the temperature of porous medium is decreased considerably with nanoparticle
volume fraction. It has been also found that the heat and mass transfer are
dramatically reduced using Water-Alumina nanofluid when compared with pure
water.
Measurement of shale gas in place based on different approaches and their comparison study
Authors: Memon Asadullah , Li Aifen , Ren Xiaoxia , Mehmood Asif , Fang Qi , Han Wencheng , Ma Min
Published: December 2019

The understanding of gas sorption mechanism is essential to characterize the original gas-in-place for shale gas reservoirs. In this study, experimental data of five shale samples have been used to estimate the shale gas-in-place with new sights. Langmuir model is commonly used to measure the amount of adsorbed gas but this model does not include the amount of absorbed gas and its behavior. However, such gas usually contributes about 22% in respect to total gas storage even though its input remains undefined. Sorption model used in this study includes adsorbed and absorbed gas. Good results are obtained from sorption model as compared to Langmuir model. Variable range of total gas storage is observed using different approaches in all shale samples. Initially at low pressure, total gas storage is observed to be higher because of gas absorption contribution in new proposed approach when compared to approach-2. When pressure increases, total gas storage is altered in keeping with characteristics of adsorption and absorption of gas. Adsorbed and sorbed porosity is estimated at two different approaches and where total gas storages capacity is affected due to adsorbed or sorbed porosity. Further, the contribution of absorbed gas amount is found at about 19-22% in respect to total gas storage in all shale samples and that is in same range as mentioned in literature. The sorption model and new proposed approach includes adsorption and absorption of gases and provides new insights to understand the gas storage mechanisms and estimation of shale gas-in-place.
The effect of the intermediate fluid-flow rate on the system performance in the closed circuit applications of the solar collector
Authors: Yildizhan Hasan , Cheema Taqi , Sivrioglu Mecit
Published: December 2019

Solar collector water heating system use solar thermal energy to provide hot water for domestic and industrial use. These systems are operated either as open-loop or closed-loop flow circuit. The former loop systems are not recommended for the cold climates having water freezing problem. Although previous studies on solar collectors have used closed-loop operation with water as the working fluid. However, it must have high boiling and low freezing points for the colder regions and thus arises the need for antifreeze mixtures of water. Another solution the same problem is the use of heat transfer oil as intermediate working fluids. In the present study, the energy and exergy analysis of a boiler supported vacuum tube solar collector system working with closed-loop in different working fluid-flow rates have been performed and evaluated. Heat transfer oil has been used as an intermediate working fluid in the closed loop system at different flow rates of 0.277 kg/s, 0.383 kg/s, and 0.494 kg/s. The results show that the collector temperature difference as well as the outlet temperature decrease. However, the collector inlet temperature increases by increasing the flow rate. Moreover, with the increase in flow rate, it was ascertained that the energy and exergy efficiency of the system and the collectors increase. The main finding of the present study is that the intermediate fluid used in the closed-circuit operation of the solar collectors has a direct effect on the energy and exergy efficiency of the system
Impact of Instituting General Anesthesia on Oral Sedation Care in a Tertiary Care Pediatric Dental Clinic
Authors: Moore David L , Ding Lili , Yang Gang , Wilson Stephen
Published: December 2019

Tertiary pediatric medical centers disproportionately care for low-income, underserved children with significant dental needs. Long wait times for hospital operating room treatment increase tooth loss rather than restoration. Oral sedation has commonly been provided to avoid the long waits for operating room treatment. However, this can be challenging with young, anxious patients. High failure rates and repeat visits for oral sedation have resulted in continued waiting for definitive dental services in the operating room. The Division of Dentistry requested the Department of Anesthesiology to create a general anesthesia program in the dental clinic to increase the use of anesthesia services but align the cost of the anesthetic with the revenue stream. Our aim was to objectively measure the performance of a dental clinic anesthesia service by comparing the percentage of case completions, percentage of complete radiographs, and number of serious adverse events to clinic-based oral sedations. We were also interested in total number of cases completed. We retrospectively studied data regarding an in-office general anesthesia (IOGA) program for dentistry and compared it to oral sedations before and after instituting the IOGA program. Patients received either a general endotracheal anesthetic or nonintubated total intravenous general anesthesia. Successful case completion increased from 88.6% (oral sedation) to 99.5% (IOGA). One hundred percent of IOGA cases had complete radiographs, as opposed to 63.4% for oral sedation. This was an increase from 53.5% from the previous 2 years with oral sedation. Serious adverse event rate was 0% (0/508) for oral sedation and 0.2% (1/418) for IOGA. Comparing 2 years before and after IOGA revealed a decrease in oral sedations from 930 to 508, whereas IOGA increased from 0 to 418 cases. Anesthesia services in dental clinic increased complete dental care and complete radiographs, reduced failed sedations, and were performed safely.
Anesthetic Management of a Patient With Fanconi Anemia
Authors: Nagano Saki , Tsukamoto Masanori , Yokoyama Takeshi
Published: December 2019

Fanconi anemia (FA) is a type of bone marrow failure syndrome based on an autosomal recessive inherited trait with increased predisposition for other cancers. It is extremely rare and is characterized by short stature, polydactyly, and pancytopenia. At present, the only effective treatment for FA is allogeneic hematopoietic stem cell transplantation (SCT). Chemotherapy is necessary prior to allogeneic SCT. Dental treatment is usually performed before chemotherapy to reduce potential infections. We experienced the anesthetic management of a 4-year-old boy diagnosed with FA, who underwent extensive dental extractions before chemotherapy for SCT. In the preoperative examination, the platelet count was decreased to less than 3.0 × 104 cells/μL because of chronic pancytopenia. The patient received 20 units of platelet transfusion over 3 days prior to anesthesia. Dental surgery and multiple dental extractions were successfully completed under general anesthesia with sevoflurane, fentanyl, and remifentanil, and chemotherapy started 3 days postoperatively.
Malignant Hyperthermia: A Case Study in the Dental Ambulatory Surgery Setting
Authors: Cornelius Bryant W. , Dib Shelby Olsen , Dowdy Regina A. , Horton Christina K. , Frimenko Katherine , Mansour Shadee , Sharkh Farah Abu , Joy Marcus T. , Hall David L. , Emam Hany A. , Jatana Courtney A. , Kennedy Kelly S.
Published: December 2019

Historically, patients who developed malignant hyperthermia had an extremely high rate of mortality. Today, if treated appropriately, patients who experience an episode of malignant hyperthermia will most likely survive. This dramatic decrease in mortality associated with malignant hyperthermia is due to several factors, including an increased understanding of the disease, improved diagnostic and monitoring equipment, and the development of lifesaving pharmacologic agents. This article presents the very likely case of acute malignant hyperthermia in a 24-year-old man with special needs, who presented for restorative dentistry under general anesthesia in the outpatient clinic of The Ohio State University's College of Dentistry.
The influence of chokeberry juice and inulin as osmotic-enriching agents in pre-treatment on polyphenols content and sensory quality of dried strawberries
Authors: Kowalska Jolanta , Lenart Andrzej , Roszkowska Sylwia , Kowalska Hanna
Published: December 2019

The objective of this study was to explain the effect of osmotic dehydration pre-treatment (chokeberry juice or inulin) and drying method (microwave-convective drying or freeze-drying) on polyphenols content, antioxidant activity and sensory properties of dried strawberries. The addition of a chokeberry juice concentrate to the osmotic solution significantly influenced the increase of polyphenols content in the fruit. Their content was significantly higher in the samples treated via osmotic dehydration in solutions containing the chokeberry juice concentrate, followed by freeze-drying and also by microwave-convective method. The ability to bind DPPH• radicals ranged from 40% in the dried strawberries without osmotic dehydration to 82% in fruit osmo-dehydrated in a mixture of inulin and the chokeberry juice concentrate and dried by freeze-drying. Study results indicate that the concentrated chokeberry juice and inulin can be used as beneficial osmotic substances. The dried strawberries can represent an alternative to snacks or may be attractive component of other products. One of the very attractive proposals for today’s increasingly demanding consumers can therefore be dried fruit snacks enriched with natural bioactive ingredients.
Ellen Thesleff 150 vuotta!
Authors: Schreck Hanna-Reetta
Published: December 2019

Pääkirjoitus
Ilman ja liikkeen fenomenologiasta
Authors: Stewen Riikka
Published: December 2019

This article discusses Ellen Thesleff’s artistic practice and suggests that it is informed by a minimalistically phenomenological attitude. Minimalist phenomenology is a term introduced by Dominique Janicaud to describe artistic practices as translations of embodied perceptual experiences comparable to philosophical efforts to define experience. It is further suggested that air and gravity play an important role in her work. Her artistic thinking is also seen in connection with the artistic practice of dancer Isadora Duncan and theatre theorist Edward Gordon Craig. The role of antiquity as imagined in early 20th century modernism is reinterpreted as a phenomenological point de repère for these artists in their pathbreaking practices
Spatial Features Transformation of Emission from Motor Vehicles in Moscow
Authors: Bityukova Viktoria R. , Mozgunov Nikita A.
Published: December 2019

The article examines changing volumes of emission from vehicles by administrative and municipal districts of Moscow. In Moscow automobile transport is the general source of pollution, it produces more than 93% of allover, and this is the absolute maximum of impact for Russian cities and regions. In 2011-2017, it was the first time when the growth of motorization was noticed against background of reduce of pollution due to modernization of car park and new quality of petrol. Total gross emission from vehicles decreased four times. Shifts in the factors defining spatial specifics of distribution of pollution from vehicles are revealed. Assessments of air pollution based on information of all Moscow streets provides estimations for 93 thousand low-level city areas. One of the research result revealed a high correlation between changes of pollution density and changes in transport infrastructure including developing of public transportation, modernization of car park structure. Spatial uniformity of pollution from vehicles has become the main trend of recent years. Programs of the new housing construction and large-scale projects aimed at the transformation of the districts increase the transport connectivity of the city. Administrative decisions on the traffic intensity reduction in the central districts decrease territorial differentiation of pollution. Transport and planning structure at the level of the city, the district, and the area is the defining characteristic. An attempt to solve the transport problem through the transformation of the street road network complicates the application of innovative techniques for combatting air pollution in Moscow.
Land-Use Change in New Moscow: First Outcomes after Five Years of Urbanization
Authors: Vasenev Viacheslav I. , Yaroslavtsev Alexey M. , Vasenev Ivan I. , Demina Sofiya A. , Dovltetyarova Elvira A.
Published: December 2019

Urbanization coincides with remarkable environmental changes, including conversion of natural landscapes into urban. Moscow megapolis is among the largest urbanized areas in Europe. An ambitious New Moscow project expanded the megapolis on extra 1500 km2 of former fallow lands, croplands and forests. The research aimed to monitor land use changes in New Moscow between 1989 and 2016 years. Landsat 5 and Landsat 8 images (30 m spectral resolution) and Sentinel – 2 images (10 m spectral resolution) were analyzed. All the images were collected for the similar summer period (from June to August). The images were preprocessed and classified by Semi-Automatic Classification Plugin in open source QGIS software to derive land cover maps. The following land cover classes were identified: water, built-up areas, bare soils, croplands and forested areas, and the total area covered by each class was estimated. The following land-use change pathways were reported: 1) reduction of the forested areas by 2.5% (almost 2000 ha) between 1989 and 1998; 2) partial reforestation (more than 1000 ha) and abandonment of croplands (more than 3000 ha) between 1998 and 2010 and 3) intensive urbanization (more than 11000 ha) between 2010 and 2016. New build-up areas and infrastructures were constructed on former forested areas and croplands. Although, some uncertainties in the absolute estimates are expected due to the classification errors, the general urbanization trend can be clearly distinguished as a principal outcome after the five years of New Moscow project.
Effectiveness of multidisciplinary team as a new model of after stroke patients’ rehabilitation
Authors: Ivanova GE , Melnikova EV , Shmonin AA , Verbitskaya EV , Belkin AA , Bodrova RA , Lebedev PV , Maltseva MN , Prokopenko SV , Prosvirnina MS , Sarana AM , Stakhovskaya LV , Suvorov AYu , Khasanova DR , Shamalov NA
Published: December 2019

Modern papers on treatment and rehabilitation of stroke patients describe the advantages and effectiveness of certain medical rehabilitation types, but these data are not enough to evaluate the efficiency of the whole rehabilitation system. The study was aimed to investigate the potential of the patient-centered problem-oriented multidisciplinary three-stage system for medical rehabilitation of stroke patients. Thestudyincluded 1021 patientsover 18 affected with ischemic or hemorrhagic stroke in the acute phase. All patients had a disability of admission at the time (but no persisting disability in their history). Two models of rehabilitation measures were compared in two consecutive phases of the study. The linear model of rehabilitation assistance was mainly implemented in phase 1, and the multidisciplinary model was implemented in phase 2. The patients’ condition was evaluated using the Modified Rankin Scale (mRS) at the end of rehabilitation. Comparison of the 1st and 2nd phase results demonstrated that the number of patients with mRS score 0–1 in the 2nd phase was lower by 18%. The proportion of patients with positive dynamics was significantly higher in the 2nd phase than in the 1st phase, (16 and 30% respectively). In the 2nd phase there were significantly more patients who demonstrated improvement by 1–4 (mRS score). Thus, the use of a multidisciplinary model provides a significant benefit compared with a linear rehabilitation model.
PENGEMBANGAN E-COMMERCE PRODUK UMKM BERBASIS ANDROID DI KOTA SERANG-BANTEN
Authors: Purbohastuti Arum Wahyuni , Aribowo Didik
Published: December 2019

Awareness of technology is increasing along with the development of technology from time to time. Sophisticated technology and its use that is easily accessible to every age group. Based on observations and interviews with the community of Micro, Small and Medium Enterprises (MSMEs) in Serang City, Banten Province, a mobile application that is capable of supporting access to information systems for MSMEproducts can be reached more widely. The objectives of this study are: 1) Developing an android-based mobile application system for marketing MSME products at the Department of Industry and Trade and MSME Serang. 2) Knowing the feasibility of an android-based mobile application system for marketing MSME products at the Department of Industry and Trade and MSME Serang City. The research method uses R&D (Research and Development) with a waterfall development model. In this waterfall development model there are four stages, namely requirements analysis, design, implementation, and testing. This research is expected to help the community, especially the SMEs in Serang City, Banten Province to be able to expand and facilitate the marketing of superior products.
Pelatihan Pemasaran Produk Olahan Telo Ungu Di Desa Wonosari Kecamatan Wonosari Gunung Kawi Kabupaten Malang
Authors: Kumala Farida Nur , Hudha Muhammad Nur , Aji Sudi Dul
Published: December 2019

Tujuan program kemitraan masyrakat ini adalah melakukan pelatihan pemasaran produk olahan telo ungu di desa Wonosari Kecamatan Wonosari Kabupaten Malang. Sebelumnya telah dilakukan pelatihan tentang pengolahan dan produksi telo ungu menjadi beberapa produk diantaranya brownies, bakpia dan stik Telo ungu.  Namun dari kegiatan tersebut terdapat kendala yakni pemasaran yang masih bersifat sederhan dan dalam lingkup yang sempit. Metode yang digunakan pada kegiatan kemitraan pada masyarakat ini dilakukan melalui tiga tahapan yakni persiapan, pelaksanaan dan evaluasi program. Program kemitraan pada masyarakat ini diikuti oleh 20 orang warga desa Wonosari Kecematan Wonosari Kabupaten Malang. Pelatihan dilakukan melalui pemasaran secara online dan offline. Hasil pelatihan didapatkan program pemasaran secara online dan offline. Pemasaran secara online dilakukan melalui media social seperti Instragram, Facebook dan Whatsapp.
Pelaksanaan Assertiveness Training Pada Anak Berhadapan dengan Hukum (ABH) di LPKA Bandung
Authors: Lestari Mutiara Ayu , Santoso Meilanny Budiarti
Published: December 2019

Jumlah Kasus Anak berhadapan dengan Hukum (ABH) setiap tahunnya terus mengalami peningkatan. Pada Tahun 2018, tercatat ada sebanyak 1434 kasus pengaduan Anak Berhadapan dengan Hukum yang diterima oleh Komisi Perlindungan Anak Indonesia (KPAI). Terdapat berbagai faktor yang berkontribusi sebagai penyebab terjadinya kasus Anak Berhadapan Dengan Hukum (ABH). Faktor yang paling mendominasi peningkatan anak berhadapan dengan hukum adalah pengaruh dari teman dan pergaulan. Teknik Assertiveness Training diterapkan sebagai upaya pencegahan peningkatan kasus Anak Berhadapan dengan Hukum melalui pemberian pemahaman kepada para anak didik (ANDIK) di LPKA Bandung mengenai penerapan perilaku asertif dalam kehidupan sehari-hari. Tujuan dari kegiatan ini adalah agar para ANDIK dapat memahami dampak dari 3 sikap dalam assertiveness training yaitu aggressive, non assertive dan assertive. Hal ini dilakukan karena sangat penting bagi seorang individu untuk menerapkan perilaku asertif dalam aktivitas sehari-hari terutama ketika seorang individu berada di dalam lingkungan masyarakat. Assertiveness Training dilakukan sebagai salah satu rangkaian praktikum Mahasiswa Kesejahteraan Sosial Universitas Padjadjaran dan juga bentuk pengabdian mahasiswa kepada para generasi penerus bangsa. Teknik Assertiveness Training dilakukan melalui metode Social Group Work bersama para ANDIK LPKA Bandung. The cases of children dealing with the law (ABH) continues to increase every year. In 2018, there were 1434 cases of Children dealing with the Law that were received by the Indonesian Child Protection Commission (KPAI). Various factors contributed as a cause of Children dealing with the Law (ABH), the most dominant factor that increased the case of children dealing with the law is the influence of friends and relationships. Assertiveness Training Technique is applied as an effort to prevent the increase of cases of Children dealing with the Law through providing understanding in LPKA Bandung regarding the application of assertive behavior in their daily lives. The purpose of this activity is that the Children can understand the impacts of 3 attitudes in assertiveness training, namely aggressive, non-assertive and assertive. This is done because an individual needs to implement assertive behavior in daily activities, especially when an individual is in a community. The Assertiveness Training is conducted as a series of social welfare programs by Padjadjaran University Social Welfare Students and also a form of devotion to the next generation of the nation. The Assertiveness Training technique is carried out through the Social Group Work method alongside the ANDIK LPKA Bandung.
Sosialisasi Pengenalan Revolusi Industri 4.0 dan Internet of Things (IoT) bagi Siswa SMAN 1 Cicalengka, Jawa Barat, Indonesia
Authors: Sari Deasy Silvya , Heryadi Dudy , Alexandri Mohammad Benny
Published: December 2019

Artikel ini bertujuan memaparkan kegiatan pengabdian pada masyarakat (PPM) yang terinterasi dengan kegiatan Kuliah Kerja Nyata Mahasiswa (KKNM) Universitas Padjadjaran dalam semester ganjil 2019 di SMAN 1 Cicalengka berupa sosialisasi mengenai pengenalan Revolusi Industri 4.0 dan Internet of Things (IoT). Metode yang dilakukan adalah eksperimen dengan mengajak para siswa untuk ikut berperan aktif dalam kegiatan sosialisasi. Selain mendengarkan materi sosialisasi, para siswa melakukan simulasi mengenai keterampilan-keterampilan sederhana terkait IoT. Hasil dari kegiatan ini menunjukkan bahwa siswa SMAN 1 Cicalengka telah mengetahui mengenai Revolusi Industri 4.0 dan tantangan yang akan dihadapi. Internet of Things (IoT) yang diperkenalkan adalah artificial intelligence (AI), esport, dan Youtube.
Boots on the streets: a “policization” of the armed forces as the new normal?
Authors: Resteigne Delphine , Manigart Philippe
Published: December 2019

The article analyses how the boundaries of postmodern military organizations are changing and how these evolutions affect their relations with the civilian society. The case of the Belgian Defence and the deployment of its military personnel in the streets are used as a case study to illustrate this transformation. Since January 2015, in response to the imminent terrorist threat in Belgium, military units have been deployed in support of the police to monitor sensitive areas, guard buildings and patrol the streets. The article analyses, first, how the population reacted to these new “proximity” roles and, second, the impact of these homeland deployments on the expeditionary readiness of the Belgian Defence and its capacity to carry out its primary missions.

The empirical analyses are, based on several quantitative and qualitative surveys, carried out among the Belgian population and the personnel of the Belgian Defence. In particular, the impact of the evolution of the public’s support over time on the blurring of the traditional roles of the military and the use of the military for internal security tasks is analysed.
Tahapan Perilaku Aktor Jaringan Komunikasi Pada Sosialisasi Isu Bullying
Authors: Arindita Ruvira , Shambodo Yoedo
Published: December 2019

Bullying has been an alarming issue for kids and teenagers nowadays. One of community that shares serious concern over this issue is Sudah Dong. This study aims to find out how the behaviour stages of actors in creating the communication networks between the volunteers of Sudah Dong community by employing the qualitative approach with in-depth interviews and observation, and theory of actor network. The result of this research revealed that the main volunteers have done the six stages of behaviour to create communication network, including problemization, interessement, enrollment, mobilization, dan inscription. Few focal actors have become the strongest nodes of the communication network and contributed much to the existence of the community. Moreover, human collectivism such as supporting organizations and private sectors were also contributing factors for the network. The non-human factors namely events and media helped attract individuals to join as volunteers. This research also found that only a few main volunteers actively participated in the community, but it was relatively effective to run the community. The shared feelings towards bullying issues and the close friendships ties were the significant factors strengthening the communication network among the main volunteers.