bluuebunny/crossref_metadata_2025 huggingface dataset:
Linked Data Generation for Adaptive Learning Analytics Systems
Authors: Lieber Sven
Published: October 2023

Did you ever use a language learning app and were annoyed that the exercises are either too easy or too hard? That are actually reasons people give up. Well, probably you would profit from adaptive learning systems, which adapt the difficulty of the exercises to your abilities!
FAIR Data Digest #10
Authors: Lieber Sven
Published: October 2023

On persistent identifiers for research and DCAT data catalogs
New Career, Same Me
Authors: Mounce Ross
Published: October 2023

This is a quick post to announce what I’ll be doing next after my postdoc at the Department of Plant Sciences, University of Cambridge. From June 2017 onwards, I’m delighted to say I’ll be the new Open Access Grants Manager for Arcadia Fund.

About Arcadia Fund

If you haven’t heard of it before here’s what you need to know: Arcadia is a charitable fund, set up by Peter Baldwin and Lisbet Rausing in 2002.
Elsevier selling access to open access again
Authors: Mounce Ross
Published: October 2023

TL;DR Elsevier are selling access to open access articles again

I saw this humorous tweet today: This tweet references the fact that Elsevier have been caught selling access to paid-for “open access” articles in 2014, 2015, and 2016.
What is Provenance?
Authors: Lieber Sven
Published: October 2023

Having Provenance or not having it, that could be worth than several hundred million dollar. Where does something come from, how was it changed since it exists, that is provenance. These informations help human beings to asses things.
Our short paper on moral dimensions of open
Authors: Taylor Mike
Published: October 2023

Back in mid-April, when I (Mike) was at the OSI2016 conference, I was involved in the “Moral Dimensions of Open” group. (It was in preparation for this that wrote the Moral Dimensions series of posts here on SV-POW!.) Like all the other groups, ours was tasked with making a presentation to the plenary session, taking questions and feedback, and presenting a version 2 on the final day. Here’s the title page that I contributed.
#OpenAccessWeek: my Jisc interview about designer labels
Authors: Taylor Mike
Published: October 2023

It’s open access week! As part of their involvement with OA Week, Jisc interviewed me. You can read the interview here. A brief taster: Read the full interview here.
Brockington Lab Weekly Research Round-Up
Authors: Mounce Ross
Published: October 2023

This week I chose the papers for the Brockington Lab ‘journal club’ here at the Department of Plant Sciences, University of Cambridge (I prefer to call it the ‘weekly research round-up’ though, because good content has nothing-to-do with

journals

per se!). We rotate the choice of papers between each lab member every week.
The unquiet corpse of Ingelfinger is still shambling around, smashing up science
Authors: Taylor Mike
Published: October 2023

It’s very doubtful that Franz J. Ingelfinger ever intended the rule named in his honour to prevent online preprints — after all, such things didn’t exist when he introduced his no-prior-publication policy at the  New England Journal of Medicine  in 1969, or even at the time of his death in 1980. Yet the rule lingers on in corrupt form.
Pricing, Citation Impact, and Springer Nature (Part 1)
Authors: Mounce Ross
Published: October 2023

On the 26

th

October 2021, Springer Nature published version 1 of a (not peer-reviewed) “white paper” titled “Going for gold: exploring the reach and impact of Gold open access articles in hybrid journals” by Christina Emery, Mithu Lucraft, Jessica Monaghan, David Stuart, and Susie Winter.
Transparency in Legislation, a must-have
Authors: Lieber Sven
Published: October 2023

The cabinet of Germany has the plan to publish the drafts of laws and associated position papers of the lobbies. This should be done for more than 600 laws of the past 4 years. This transparency can reveal a lot. For instance, which Lobby influenced which law actively. Nearly 17,000 documents are planned to be published. But how can one handle this huge amount?
Tutorial 31: ways to start a new open-access journal
Authors: Taylor Mike
Published: October 2023

A few months ago I got an email from Nathan Myers, who asked me: In many ways, I’m the wrong person to ask: I’ve never started a journal, OA or otherwise, nor even served on an editorial board. But, hey, I’m not one to let something like that stop me. So here’s what I told Nathan. I’m sure I missed a lot of important possibilities: please point them out in this comments. I’ll try to keep this post updated as the landscape changes.
ISWS 2018 Poster
Authors: Lieber Sven
Published: October 2023

For the ISWS summer school I prepared an interactive poster. Read in his post what it is about and see how it was made. My summer this year will start with the attendance of the International Semantic Web Research Summer School (ISWS) in Bertinoro, Italy. For that we were invited to bring a poster, describing our PhD research. My current research tasks involve so called shapes, describing data within a graph of information.
Documenting the many failures across OUP journals
Authors: Mounce Ross
Published: October 2023

Updated 2017-02-01: Mathematical equation rendering failures spotted at the journal ‘Molecular Biology & Evolution’ (MBE). Added to the lengthy list.

In this post I shall try and summarise the different types of error that are occurring across Oxford University Press (OUP) journals at the moment.
Hybrid open access is unreliable
Authors: Mounce Ross
Published: October 2023

The TL;DR summary: In February 2017, when Elsevier were accused of selling one paid-for hybrid open access article, at first they sowed doubt about it, then three days later admitted it to be true. In their admission they state that it is the only wrongly paywalled open access article “affected” at their websites.
Elsevier has started destroying SSRN
Authors: Taylor Mike
Published: October 2023

As predicted, the popular and useful Social Sciences repository SSRN, having been acquired by Elsevier, is now being destroyed.
Knowledge Graphs for Data Integration - UHasselt 2023
Authors: Lieber Sven
Published: October 2023

In June 2023 I attended a workshop in Hasselt, Belgium, organized by a research network on Knowledge Graphs and Data Integration. Linked Data-based systems and declarative SPARQL queries somehow magically do all the work efficiently, but how? For many people, presentations about  using  Linked Data and SPARQL already seem very technical. But this event went further, it covered the fundamental algorithms that power the Linked Data systems!
Seeking Justice for Readers
Authors: Mounce Ross
Published: October 2023

I am highly curious as to why Elsevier do not seem to be responding to emails at the moment: Four days ago, continuing an existing thread on the public GOAL mailing list, I wrote to Dr Alicia Wise (Director of Access and Policy at Elsevier), about how Elsevier’s paywall systems are wrongly defrauding readers across the world by charging them to access content that has been paid-for to be open access.
Suppression as a form of liberation?
Authors: Mounce Ross
Published: October 2023

On Monday 29th June 2020, I learned from Retraction Watch that Clarivate, the for-profit proprietor of

Journal Impact Factor

™ has newly “suppressed” 33 journals from their indexing service.
Remarkable ongoing chaos at OUP
Authors: Mounce Ross
Published: October 2023

Just a quick post tonight. Yet another paywalled open access article. It’s becoming a daily occurrence!
Increase in the Amount of Soil Organic Matter and Populations of Microorganisms by Addition of Different Types of Compost for Sustainable Agriculture
Authors: Kabaivanova L. , Nacheva L. , Goushterova A. , Dinev N.
Published: October 2023

Maintaining a positive balance of organic matter in arable land is a fundamental issue for sustain¬able agriculture. Environmentally friendly and cost-effective solutions applicable to large areas and also to small farms are needed. This is especially true for areas affected by environmental processes, leading to deteriorating soil fertility and limiting opportunities for organic farming. Organic fertilization through composting is an effective method of maintaining soil fertility. Due to shortage of traditional organic fertil¬izers, new sources of organic matter are being sought, such as agricultural waste, sewage sludge, household or industrial waste. Identification of waste products and possibilities for their use in compost production with a certain composition was carried out. Physico-chemical characteristics of the starting materials be¬fore composting was carried out. Estimation of their effectiveness as soil improvers on two types of soils - leached cinnamon forest soil from the area of village of Chelopechene, near Sofia, Bulgaria and alluvial meadow soil from the area of Tsalapitsa, Plovdiv region, Bulgaria was accomplished. When composting the ameliorants with the first type of soil, all additives led to positive changes in soil organic matter, while composting ameliorants with the second type of soil, the added organic materials provided a lower degree of storage of organic matter. Therefore, compost addition to leached cinnamon forest soil is more reason¬able, ensuring good stock in the form of humin. Application of compost led to increase in the populations microorganisms, including bacteria and fungi, which is a good indicator of increased soil microbial activity in respective treatments.
Koi Herpesvirus Highlights and Potential of Probiotics to Reduce or Even to Prevent Koi Herpesvirus Infection
Authors: Mancheva K. , Danova S. , Vilhelmova-Ilieva N. , Simeonova L. , Dobreva L. , Atanasov G.
Published: October 2023

Koi herpesvirus (KHV) is a highly contagious virus that causes high morbidity and mass mortality of koi carp (Cyprinus rubrofuscus Lacepède, 1803), common carp (Cyprinus carpio Linnaeus, 1758) and its ornamental (coloured) varieties. Koi herpesvirus disease (KHVD) is one of the major factors that cause sig¬nificant economic losses affecting both wild and cultured populations of common and koi carp worldwide. It is thought that there is no effective treatment for KHVD. The usage of vaccines for aquatic animals and water environments is limited, associated with the risk of viral reactivation and reversion to virulence. In Europe, for example, no commercial vaccine for KHVD is available. On the other side, probiotic additives are one of the most prospective, promising, and safe alternatives of drugs, that provide fish health benefits such as improvement of fish immune resistance and increased growth performance. This paper provides a thoroughgoing analysis of the knowledge about Koi herpesvirus and the disease, its distribution, and con¬ventional treatment methods. We discuss the potential of probiotics for improvement of growth rate and carp immune resistance, associated with the fish mucosal immune system as the first immune barrier.
The Immunology of Malaria: А Review
Authors: Falade I.J. , Simeon O.N.
Published: October 2023

Plasmodium falciparum malaria is still very much regarded as a global health challenge recording morbidity close to half a million annually. Special attention has been given to Plasmodium due to this high rate of morbidity. The steps taken towards control have produced a considerable result. Some of these steps are aimed at controlling the vector hosting P. falciparum or a nib in the bud during the several stages of P. falciparum invasion in humans. These controls include effective antimalarials, the use of insecticide-treated nets (ITNs), indoor residual spraying (IRS) campaign, and vaccine. Several vaccines have been tested but none came close in success to the recent vaccine (RTS, S/AS01) which was approved for pilot implementa¬tion program in three African countries in 2015. However, despite the success recorded, this vaccine has its limitations, which include low efficacy in certain age groups, poor immunogenicity, and the need for sev¬eral booster doses to achieve reasonable effectiveness. With this in mind, an intentional search for a more effective vaccine is still ongoing and an understanding of naturally acquired immune responses would help in vaccine design. This review put together what is currently known about P. falciparum and the immune responses against malaria.
Real Time Quantitative PCR as Detection Method for CMV Reactivation in Patients with Lymphomas – a Single-Center Experience
Authors: Stoykova Z. , Kostadinova T. , Todorova T. , Ivanova L. , Kalchev K. , Micheva I.
Published: October 2023

Cytomegalovirus (CMV) becomes an important pathogen in individuals whose immune system is compromised like patients with various types of lymphomas. Our goal was to estimate the deal of CMV reactivation in RT PCR during the treatment course, considering the seroprevalence of 49 patients with lymphomas from the Clinic of Hematology “St. Marina” University Hospital, Varna. We used commercial ELISA and quantitative RT-PCR for CMV detection. We found 90% (95% CI: 78.9% - 97%) of the patients anti-CMV IgG positive. In addition, we found 10% (95% CI: 1.6% - 18.3%) of them PCR positive (range 2 332 - 5 688 IU/ml). The highest viral loads were detected in 3 patients with non-Hodgkin’s lymphoma (NHL), histologic variant “diffuse B-cell giant cell lymphoma”. In conclusion, approximately 10% of pa¬tients with ML reactivate their latent CMV infection during the treatment of the main disease. Because IgM alone cannot serve as a reactivation marker, qRT-PCR is a reliable method for early identification of CMV reactivation and would assist for better management and prevention of complications in this high risk group of patients.
Evaluation of Antimicrobial Activities of Different Extracts from Phlomis tuberosa, Abutilon fruticosum, and Nepeta transcaucasica
Authors: Asnaashari S. , Heshmati-Afshar F. , Amin-Aghdam N. , Asgharian P. , Hallaj-Nezhadi S.
Published: October 2023

The use of medicinal plants for the natural treatment of infections has received much attention. Pre¬viously, plants of Nepeta, Phlomis, and Abutilon genera showed remarkable antimicrobial activities. We aimed to evaluate the antimicrobial effects of three Iranian plants including Abutilon fruticosum Guill. & Perr., Nepeta transcaucasica Grossh., and Phlomis tuberosa (L.) Moench. Aerial parts of the plants were extracted by the maceration method using petroleum ether, chloroform, ethyl acetate (EtAc), and methanol solvents. The antimicrobial activity of the extracts against seven Gram-positive strains and three Gram-neg-ative strains was studied via the disk diffusion method. Potent extracts were fractionated and diameters of the inhibition zone (DIZ) and Minimum Inhibitory Concentration (MIC) were determined. The chloroform extract of N. transcaucasica and EtAc extract of A. fruticosum were the most active extracts. Staphylococ¬cus aureus, was the most sensitive strain to N. transcaucasica (DIZ=17 mm, MIC=3.125 mg/ml), whereas S. epidermidis (DIZ=15 mm, MIC=1.56 mg/ml), and Bacillus subtilis (DIZ=13mm, MIC=0.39 mg/ml) were the most sensitive bacteria to A. fruticosum. Fractions of 40% and 60% EtAc/n-hexane of chloroform extract of N. transcaucasica and fractions of 40%-100% of EtAc extract of A. fruticusum revealed the potent activities. B. cereus was “very sensitive” to 60%-100% fractions of chloroform extract of N. trans¬caucasica (DIZ=16–19 mm, MIC=12.5 mg/ml). S. pneumoniae was “extremely” (DIZ=20 mm) sensitive to the 60% Ethyl acetate fraction of A. fruticosum and noticeably, their antimicrobial effects were greater than that of the standard antibiotic. The results support some of the traditional applications of the studied plants.
Antifungal Susceptibility Pattern of Malassezia sp. Isolated from the North-East Region of India
Authors: Marak E.K. , Singh Th.N. , Devi Kh.S. , Singh Y.R.B. , Devi Kh.R.
Published: October 2023

Malassezia comprises lipophilic yeasts which are considered as commensals of the skin and become pathogenic under certain conditions. One hundred and forty-four specimens from clinically suspected cas¬es of pityriasis versicolor were collected and processed microbiologically. Malassezia sp. was identified phenotypically and MIC for common antifungal drugs was performed. Thirty-three percent of the collected specimens were culture positive for Malassezia sp. M. furfur (50%) is the commonest species isolated from pityriasis versicolor cases, followed by M. globosa (35.4%). The study observed low MICs for itraconazole and voriconazole. Itraconazole is the choice of drug for the treatment of Malassezia infection.
KẾT QUẢ ĐIỀU TRỊ 60 BỆNH NHÂN U PHÌ ĐẠI LÀNH TÍNH TUYẾN TIỀN LIỆT BẰNG NỘI SOI NIỆU ĐẠO VỚI NĂNG LƯỢNG LASER THULIUM, TẠI BỆNH VIỆN QUÂN Y 110
Authors: Nguyễn Hoàng Hiệp  , Nguyễn Xuân Phúc  , Nguyễn Văn Tuấn  , Nguyễn Hồng Việt
Published: October 2023

Mục tiêu: Đánh giá kết quả điều trị u phì đại lành tính tuyến tiền liệt bằng cắt đốt và bốc hơi nội soi qua niệu đạo với năng lượng LASER Thulium, tại Bệnh viện Quân y 110.

Đối tượng và phương pháp: Nghiên cứu tiến cứu mô tả, cắt ngang 60 bệnh nhân u phì đại lành tính tuyến tiền liệt, được phẫu thuật cắt đốt và bốc hơi nội soi qua niệu đạo với năng lượng LASER Thulium. Đánh giá kết quả phẫu thuật qua thang điểm IPSS, thang điểm QoL và các biến chứng tại thời điểm sau phẫu thuật 1 tháng, 3 tháng.

Kết quả: Bệnh nhân nghiên cứu trung bình 73,17 tuổi. Thể tích tuyến tiền liệt phân bố từ 39-80 gam (trung bình 57,78 + 15,24 gam). Thời gian phẫu thuật từ 34-95 phút (trung bình 60,25 ± 11,46 phút). Lượng dịch rửa trong phẫu thuật từ 19-43 lít (trung bình 34,27 ± 7,39 lít). Thời gian tưới rửa sau phẫu thuật từ 1-3 ngày (trung bình 1,35 ± 0,36 ngày). Thời gian lưu thông niệu đạo sau mổ từ 2-4 ngày (trung bình 2,14 ± 0,47 ngày). Không bệnh nhân nào gặp hội chứng nội soi hoặc chảy máu phải truyền máu. Thời gian nằm viện sau mổ của bệnh nhân từ 3-5 ngày (trung bình 3,58 ± 0,62 ngày). Tỉ lệ bệnh nhân tiểu máu sau mổ 3,34% và chỉ cần điều trị bằng các thuốc cầm máu thông thường. Sau phẫu thuật 1 tháng và 3 tháng, điểm IPSS trung bình (8,03 ± 1,8 điểm và 7,23 ± 2,69 điểm), điểm QoL trung bình (2,15 ± 0,72 điểm và 1,93 ± 0,61 điểm) của các bệnh nhân nghiên cứu đều thay đổi so với trước phẫu thuật (IPSS: 30,06 ± 3,57 điểm; QoL: 4,78 ± 0,71 điểm) có ý nghĩa thống kê.
ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ 109 BỆNH NHÂN CHẢY MÁU MŨI, TẠI BỆNH VIỆN QUÂN Y 110, TỪ THÁNG 01/2021 ĐẾN 12/2022
Authors: Thân Thế Dũng  , Thân Văn Thương
Published: October 2023

Mục tiêu: Nghiên cứu đặc điểm lâm sàng và kết quả điều trị chảy máu mũi tại Bệnh viện Quân y 110.

Đối tượng và phương pháp: Nghiên cứu tiến cứu, mô tả cắt ngang 109 bệnh nhân chảy máu mũi, vào điều trị tại Bệnh viện Quân y 110, từ tháng 1/2021 đến 12/2022.

Kết quả: Hay gặp chảy máu mũi ở bệnh nhân nam giới (87,2%), từ 40 tuổi trở lên (51,4%), vào thời điểm mùa Đông-Xuân (67,9%), trên người có bệnh lí nền tăng huyết áp (74,3%) và chảy máu mũi mức độ nhẹ (75,2%). Với các bệnh nhân chảy máu mũi mức độ nhẹ, xử trí chủ yếu là tiêm cầm máu và nhét merocell mũi. Với các bệnh nhân chảy máu mũi mức độ nặng hoặc chảy máu mũi dai dẳng, tái phát nhiều lần, cần điều trị bằng nội soi đông điện cầm máu khi các kĩ thuật khác thất bại. Tỉ lệ thành công của kĩ thuật tiêm thuốc cầm máu là 15/109 bệnh nhân (13,8%), nhét merocell mũi là 52/94 bệnh nhân (55,3%) và nội soi đông điện là 41/42 bệnh nhân (97,6%); thời gian nằm viện trung bình là 6,8 ngày.
NHẬN XÉT ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ PHẪU THUẬT ĐIỀU TRỊ NANG CUỐNG RĂNG, TẠI BỆNH VIỆN QUÂN Y 110
Authors: Nguyễn Văn Thăng  , Dương Đức Phong
Published: October 2023

Mục tiêu: Nhận xét đặc điểm lâm sàng, cận lâm sàng và kết quả phẫu thuật điều trị nang cuống răng.

Đối tượng và phương pháp: Hồi cứu kết hợp tiến cứu mô tả cắt ngang 58 bệnh nhân nang cuống răng, điều trị phẫu thuật tại Khoa Răng hàm mặt, Bệnh viện Quân y 110, từ tháng 01/2016-3/2023.

Kết quả: Bệnh nhân nang cuống răng điều trị phẫu thuật tại Bệnh viện Quân y 110 phân bố từ 27-72 tuổi, trong đó 51,7% bệnh nhân từ 30-49 tuổi; tỉ lệ bệnh nhân nam là 41,4% và nữ là 58,6%. Đa số bệnh nhân mắc bệnh từ 6-12 tháng (69,0%), nguyên nhân do chấn thương (62,1%). Lâm sàng biểu hiện các triệu chứng: lợi sưng nề/đỏ (93,1%), đau răng (86,2%), rò mủ tại chỗ (72,4%), răng đổi màu (65,5%), răng lung lay tương ứng vị trí nang (51,7%), phồng xương (43,1%), biến dạng mặt (13,8) và 34,5% bệnh nhân không có triệu chứng (tình cờ phát hiện bệnh qua chụp X quang). Về kích thước nang cuống răng: 48,3% bệnh nhân có nang dưới 2 cm; 27,6% bệnh nhân có nang từ 2-3 cm và 24,1% bệnh nhân có nang trên 3 cm. Về phương pháp điều trị, có 72,4% bệnh nhân phẫu thuật cắt nang và cắt cuống răng; 27,6% bệnh nhân phẫu thuật cắt nang và nhổ răng. Kết quả gần: tốt chiếm 89,7%; khá chiếm 6,9% và kém chiếm 3,4%. Kết quả xa: tốt chiếm 93,1% và khá chiếm 9,6%.
ĐẶC ĐIỂM BỆNH LÍ VÀ KẾT QUẢ ĐIỀU TRỊ 36 BỆNH NHÂN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ CÓ ĐỘT BIẾN GEN EGFR BẰNG THUỐC ỨC CHẾ TYROSIN KYNASE, TẠI BỆNH VIỆN QUÂN Y 110
Authors: Đào Thanh Hoàn  , Lê Khắc Hiệp  , Nguyễn Văn Giang  , Nguyễn Văn Kiên  , Phạm Thị Hồng Thắm
Published: October 2023

Mục tiêu: Nhận xét đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị các bệnh nhân ung thư phổi không tế bào nhỏ có đột biến gen EGFR bằng thuốc ức chế tyrosin kynase.

Đối tượng, phương pháp: Nghiên cứu tiến cứu, mô tả cắt ngang và theo dõi dọc 36 bệnh nhân chẩn đoán xác định ung thư phổi không tế bào nhỏ có đột biến gen EGFR, điều trị bằng thuốc ức chế tyrosin kynase, tại Khoa Ung bướu, Bệnh viện Quân y 110, từ tháng 01/2019 đến tháng 10/2022.

Kết quả: Bệnh nhân trung bình 64,2 ± 9,1 tuổi, độ tuổi từ 60-69 tuổi chiếm 41,7%. Tỉ lệ giới tính bệnh nhân nam/nữ = 1,4/1. Đa số bệnh nhân không có tiền sử mắc bệnh nội khoa (83,4%), không có tiền sử hút thuốc (52,8%), có toàn trạng khá và tốt (88,8%), bệnh ở giai đoạn di căn xa (91,7%). Triệu chứng thường gặp là đau tức ngực (47,2%), ho khan kéo dài (47,2%). Đột biến gen EGFR ở vị trí exon 19 chiếm tỉ lệ 52,8%. Kết quả điều trị bằng thuốc ức chế tyrosin kynase: 91,7% bệnh nhân thuyên giảm các triệu chứng lâm sàng; 63,9% bệnh nhân đáp ứng điều trị một phần. Kiểm soát bệnh đạt 91,7%. Trung vị thời gian sống thêm toàn bộ đạt 22 tháng, dài hơn ở các bệnh nhân có đột biến gen EGFR exon 19 (p < 0,05). Tác dụng không mong muốn hay gặp là nổi ban da (47,2%), viêm kẽ móng (25%) mức độ nhẹ đến vừa.
ĐÁNH GIÁ HIỆU QUẢ PHỐI HỢP BÀI THUỐC TK1 VỚI ĐIỆN CHÂM TRONG ĐIỀU TRỊ 68 BỆNH NHÂN THOÁI HÓA KHỚP GỐI, TẠI BỆNH VIỆN QUÂN Y 110
Authors: Đặng Phương Phương  , Ngô Trọng Lượng  , Lê Văn Bình  , Nguyễn Hữu Nhẫn
Published: October 2023

Mục tiêu: Đánh giá hiệu quả phối hợp bài thuốc TK1 với điện châm trong điều trị thoái hóa khớp gối.

Đối tượng, phương pháp: Nghiên cứu mô tả cắt ngang có so sánh trước và sau điều trị trên 68 bệnh nhân thoái hóa khớp gối, tại Bệnh viện Quân y 110, từ tháng 4/2019 đến tháng 12/2022. Đánh giá mức độ đau khớp gối theo thang điểm VAS. Đánh giá mức độ nặng của thoái hóa khớp theo chỉ số Lequesne. Đánh giá chức năng vận động khớp gối theo phương pháp Zero và chỉ số gót-mông.

Kết quả: Về hiệu quả giảm đau, sau 30 ngày điều trị, tỉ lệ bệnh nhân không đau và đau nhẹ giảm còn 88,3%, không còn bệnh nhân đau nặng; hiệu suất cải thiện chỉ số VAS trung bình là 4,50 ± 1,05 (điểm). Về hiệu quả cải thiện mức độ nặng của thoái hóa khớp gối, chỉ số Lequesne trung bình trên các bệnh nhân sau điều trị 15 ngày (6,45 ± 2,31 điểm) và 30 ngày (3,47 ± 1,50 điểm) cải thiện có ý nghĩa thống kê so với trước điều trị (10,06 ± 2,32 điểm). Về chức năng vận động khớp gối, sau điều trị 30 ngày, tầm vận động khớp gối thay đổi rõ rệt, khác biệt giữa trước và sau điều trị có ý nghĩa thống kê, với p < 0,05. Phương pháp điều trị không gây ra các tác dụng không mong muốn trên lâm sàng.
Inhibition of IgE Activity to Bind its High Affinity Receptor (FcεRIα) by Mouse Anti-IgE Ce3~4 Monoclonal Antibody (QME5)
Authors:   Institute of Basic Medical Sciences, Beijing, P. R. China, Feng Jian Nan , Hua Xiao Li ,   Medical Biotechnology Institute and Clinical Immunology Laboratory, Suzhou University, Suzhou, P. R. China, Qiao Chun Xia , Lv Ming , Guo Lei Ming , Yu Ming , Li Yan , Lin Zhou , Hou Chun Mei , Shen Bei Fen ,   Institute of Basic Medical Sciences, Beijing, P. R. China
Published: October 2023

Using computer-guided homology modeling method, the 3-D structure of the Fv fragment of a functional anti-IgE antibody (MAE11) was constructed and the spatial structure of E24-MAE11 complex was modeled based on the crystal structure of IgE-Fc (abbr. E24) and molecular docking method. Then the identified epitope of IgE was determined theoretically, which showed the key role of IgE-Cε3 in interacting with both FcεRIα and MAE11. By normal protocols, we immunized mice with purified protein E34 and screened six anti-E34 monoclonal antibodies. Purified antibodies could identify E34 by Western blot; furthermore, all of them could bind IgE by ELISA, in which QME5 seemed to be the best. Flow cytometry analysis displayed that only QME5 could bind membrane IgE and it could compete with membrane FcεRIα to bind soluble IgE. Meanwhile, QME5 couldn't bind FcεRIα-attached IgE, which suggested no hypersensitivity in triggering the target cells (mast cells or basophils) by crosslinking or inducing the release of a variety of chemical mediators.
Standardization of a Method to Evaluate the Antioxidant Capacity of High-Density Lipoproteins
Authors:   Department of Biochemistry, Institut de Recerca, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, Sanchez-Quesada Jose Luis , Juan-Franco lena de , Ribas Vicent ,   Department of Biochemistry, Institut de Recerca, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, Perez Antonio ,   Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, Sanchez-Hernandez Juan Antonio ,   CIBER de Diabetes y Enfermedades Metabolicas Asociadas CIBERDEM, Blanco-Vaca Francisco , Ordonez-Llanos Jordi ,   Department of Biochemistry and Molecular Biology, Universitat Autonoma de Barcelona, Barcelona, Spain
Published: October 2023

Background: A method to evaluate the antioxidant capacity of high-density lipoprotein (HDL) was developed and standardized. Methods: This method measure conjugated diene (CD) formation and electrophoretic mobility of low-density lipoprotein (LDL) in agarose gels in the presence and absence of HDL. HDL was isolated from 1 mL of plasma within 24 hours and oxidation assays were performed within 6 hours. Oxidation was induced by adding CuSO4. The lag phase increase in CD kinetics and the inhibition of electrophoretic mobility were defined as the HDL antioxidant capacity. Results: The optimal conditions for the CD assay were 2.5 μM CuSO4, LDL at 0.1 g apoB/L, HDL at 0.1 g apoA-I/L, at 37ºC and for 3h 50 min. Agarose electrophoresis at 100 V, at 4ºC for 50 min was then performed immediately. CD formation variability was 21.1% for inter-assay CV and 12.7% for intra-assay CV. Electrophoretic mobility was 26.5% for inter-assay CV and 2.4% for intra-assay CV. Correlation analysis showed a significant association between the antioxidant capacity of HDL and its neutral/polar lipid ratio. Conclusions: The method herein described measures of the HDL antioxidant capacity in a reproducible and rapid manner that can be applied to a relatively high number of samples.
Butte Mine Flooding Operable Unit water-level monitoring and water-quality sampling 2021 consent decree update Butte, Montana, 1982-2021
Authors:   Montana Bureau of Mines and Geology, Duaime T.E. , McGrath S.F. , Icopini G.A.
Published: October 2023

Summary of 2021 monitoring and sampling results, combined with long-term data/trends.
Effect of Work Environment and Work Discipline on Employee Performance in the District Office Majalaya, Karawang District
Authors: Pitrianti Iim , Rismayadi Budi , Sumarni Neni
Published: October 2023

The purpose of this study was to see and assess how the work environment and work discipline affect the performance of employees in the Majalaya District office, Karawang Regency. Quantitative research methodology is used in this study. The distribution of questionnaires, interviews and observations are data collection methods in this study. By using a saturated sample of 40 employees at the Majalaya District office, the sample is determined. The data analysis technique used validity test, reliability test, normality test, heteroscedasticity test, multiple analysis technique, coefficient of determination, significance test. The results showed that the factors of the work environment and work discipline which were studied partially and simultaneously had a major effect on the performance of employees at the Majalaya District office, Karawang Regency.
Industrial competitiveness and FDI opportunities in the metropolitan periphery - product space network analysis of Laval, Canada
Authors: WANG Yihan , TURKINA Ekaterina , LEMAY Normand
Published: October 2023

This paper investigates the industrial competitiveness and FDI opportunities in the metropolitan periphery embedded in the product space network. Assessing the knowledge complexity and revealed competitive advantage (RCA) of local industries, entrepreneurs and policymakers can identify the most prominent ones and implement competitive strategy accordingly. Complementarily, they can attract FDI inflows in non-RCA structural hole sectors of close knowledge proximity with existing RCA sectors in the product space network. In the case study of Laval, Canada, we conduct quantitative product space network analysis and qualitative thematic analysis on the semistructured interviews with entrepreneurs and policymakers to address these points.
The power of syndication: the innovation output of venture capital investments in the United States
Authors: SHUWAIKH Fatima , DIAS Joakim
Published: October 2023

This paper demonstrates the impact of the participation of corporate venture capital (CVC) funds and independent venture capital (IVC) funds in syndicated investments. We examine the dynamics of the impact of these syndications and the channels (industry fit and location fit) that improve innovation effectiveness. Based on the main sample of 5182 US. funded companies between 1998 and 2017, there is strong evidence of an existing superiority of CVC engagement in syndications (CVC/IVC) that can further boost the innovation output contribution. Additionally, the results show that industry and location fit augment the innovation output of the entrepreneurial companies.
CEO overconfidence and tax practices: Does board gender diversity matter?
Authors: LAKHAL Faten , KHEMIRI Sabrina , BACHA Sami , GUIZANI Assil
Published: October 2023

This study examines the effect of chief executive officer (CEO) overconfidence on tax avoidance practices. Based on a sample of French-listed firms, the results show that overconfident CEOs engage in high levels of tax avoidance suggesting that the overconfidence bias may lead CEOs’ to behave unethically and use deceitful tactics to avoid taxes. However, board gender diversity mitigates this behavior suggesting that female directors are good monitors on the board. Our findings give insights to policymakers who may consider gender diversity on top management positions in addition to the board of directors to prevent a loss in tax revenues.
Saved by trust: when extensive supply chain integration becomes detrimental
Authors: HAMDI Ahmed , SAIKOUK Tarik , BAHLI Bouchaib , ANAND Amitabh
Published: October 2023

This paper refines existing literature on supply chain integration (SCI) by exploring its possible adverse effects on higher levels of SCI on firm performance. Furthermore, we explain how trust offsets the negative effects of increased integration. Based on data gathered from 152 firms in the United States, our research reveals two important results: (1) an inverted U-shaped relationship exists between supplier integration and firm performance, (2) the levels of trust attenuate the effects of increased integration on firm performance. Finally, using the relational view and transaction costs theory, we discuss the theoretical and managerial implications of our research results.
RELATIONSHIP BETWEEN PHYSICOCHEMICAL PARAMETERS AND ANTIMICROBIAL ACTIVITY OF MOLDAVIAN HONEY
Authors: Eremia Nicolae , Coșeleva Olga , Sucman Natalia , Balan Greta , Lupașcu Lucian , Mardari Tatiana , Modvala Susana , Macaev Fliur
Published: October 2023

Six samples of Moldavian honey from different regions were analyzed, physical and chemical parameters, the content of macro-, microelements, and aminoacids were determined, as well as antibacterial and antifungal activity. The antibacterial and antifungal properties were determined using the double serial dilution method. It was established that all of the samples of acacia, linden, and sunflower honey possess high antibacterial activity. The bioactivity of the samples of honey was proven to be dependent on the type and origin of honey. Sunflower honey has higher antibacterial potency than linden, but linden honey is more active than acacia. Both Gram-positive and Gram-negative bacterial species proved to be susceptible to Moldavian honey. Acacia, linden, and sunflower honey, possess high antibacterial potency against S. aureus and P. aeruginosa even at a dilution of 1:16 (2.5%). The studied samples showed weak antifungal activity against Candida albicans, with the MIC determined at 1:2 dilution (20%). For linden and sunflower honey, the antifungal activity was higher than for acacia honey. The samples with the best bioactivity (sunflower honey) contain a higher amount of free acids, had lower pH values of the honey solution, and these samples also have the highest content of OMF.
Determinación del campo de velocidad en una válvula magnetoreológica con efecto de deslizamiento hidrodinámico
Authors: Gómez López Juan Rolando , Escandón Colin Juan Pablo
Published: October 2023

El presente trabajo analiza el comportamiento de una válvula magnetoreológica (MR) en presencia de un campo magnético aplicado. Se asume que el fluido MR modifica su comportamiento reológico a partir del esfuerzo de fluencia, resultando en un flujo con una combinación entre una fase sólida y líquida. Para simular este fenómeno de flujo, se utiliza el modelo de Herschel-Bulkley con las ecuaciones gobernantes descritas por las ecuaciones de continuidad y de cantidad de movimiento para un fluido incompresible. En el análisis se considera que las paredes del conducto que forman la válvula MR han sufrido desgaste y, por tanto, se presenta un deslizamiento hidrodinámico. Los resultados se presentan en función de perfiles de velocidad que dependen de los parámetros adimensionales que surgen del modelo matemático. Estos son el gradiente de presión, el esfuerzo de fluencia, el índice de ley de potencia, la razón de viscosidad y el deslizamiento hidrodinámico.
Uncertainty analysis of the dual-lift use case for the industrial wireless testbed
Authors: Montgomery Karl , Candell Richard , Hany Mohamed
Published: October 2023

This report serves to characterize the uncertainty of measurements for key performance indicators (KPIs) used to measure the physical and network performance of the NIST industrial wireless dual-lift testbed. A review of the methods used to determine uncertainty is presented. We use the method known as the Guide to the Expression of Uncertainty in Measurement (GUM) to calculate the uncertainty values for each measurement. A description of the dual-lift use case and the KPIs are presented. The resulting expanded uncertainty values are calculated for the KPIs, which are the positional Cartesian error between the leader and follower robots, and the latency of the data packets associated with the informational transactions of the leader and follower’s control loop. It is concluded that the measurement systems used in the dual-lift use case have relatively small uncertainty values for the detection of latency perturbations in the real-time control application
implemented on the testbed.
Introgression of cytoplasmic male sterility (CMS) in tropical carrots (Daucus carota subsp. sativus Schubl. & Martens)
Authors: Singh BK , Karmakar Pradip
Published: October 2023

The petaloid-CMS plants identified in naturally occurring open-pollinated population were used for introgression of male sterility in two varieties (Kashi Arun and Kashi Krishna) and 11 advanced elite materials of tropical carrot through backcrossing at ICAR-IIVR, Jakhini, Varanasi, UP. The tropical varieties and elite materials having diverse morphological backgrounds i.e. root colour (Red, Orange, Yellow, Rainbow, Black & White) and root shape (Danvers, Nantes & Kuroda) were used as recurrent parent in order to recover their background. Thirteen CMS-lines [VRCAR-211, VRCAR-212 & VRCAR-214 (red root); VRCAR-231, VRCAR- 234 & VRCAR-241 (orange root); VRCAR-271 & VRCAR- 272 (yellow root), VRCAR-291 & VRCAR-292 (rainbow root), VRCAR-251 & VRCAR-252 (black root), and VRCAR-331 (white root)] and their respective maintainers were similar in root colour, root shape and synchronous in flowering/ pollination activities which may be used for heterosis breeding for development of nutrient-rich hybrids suitable for tropical/sub-tropical conditions.
Conservation of Urban Heritage Landscapes: Lessons from Souq AlSaffarin in Baghdad, Iraq
Authors: Albayati Rasha , Alobaydi Dhirgham
Published: October 2023

For centuries, traditional bazaars, or Souqs have been integral to urban life and the economic landscapes of Arabic-Islamic regions. The tangible and intangible heritage that shapes the identity of a place and contributes to its economy is essential to the functioning of these bazaars. With appropriate spatial configurations, they could foster creative industries, handcrafts, and customs, which can generate new services, create jobs, diversify a city’s economic distribution and promote small businesses. This paper explores Souq alsaffarin, which is also known as the copper market in old Rusafa in Baghdad. It is a heritage urban landscape and has a role in shaping the sense of place in this area. It has been subject to many socio-economic and political events that have influenced the importance and character of its profession, in terms of production and selling. It is a landmark of Baghdad that has maintained its position despite difficulties. The distinctive handicrafts produced and their relationships with people’s social practices highlight their impact on tourism and their role as an economic source for the region. They provide economic permanence that helps to develop the historical core of the city, preserve its historical identity, and promote cultural tourism. However, the market faces a significant problem of declining numbers of shopkeepers and craftsmen, which threatens the continuation of its local small businesses. This research examines this issue. It employs site observations, questionnaires, and interviews with craftsmen and shop owners who still run the market, as a research methodology. SWOT analysis is employed to identify the best solutions to develop the souq and preserve its identity. The paper concludes that the significance of Souq Alsaffarin lies in its deep connection to the rich history and culture, which defines the identity and heritage of the community. Thus, it argues that preservation and conservation are essential. This requires an approach that considers both tangible and intangible aspects of the souq, engaging the local community, and promoting sustainable practices, so that this souq can thrive as a living testament to its rich history and culture.
“Mamuli” Pattern in East Sumba Woven Fabric as Inspiration For “Kandunnu” Standing Lamp Using the IMOE Method
Authors: Halim Erwin Ardianto , Joneurairatana Eakachat , Vongphantuset Jirawat , Jamuni Pairoj
Published: October 2023

Inspiration is a crucial factor in the conception and development of innovative design products. In the contemporary creative world, an innovative product transcends mere aesthetic factors, encompassing intrinsic values. This study investigates a framework for transforming Mamuli pattern, found in East Sumba woven fabric, into a contemporary and innovative product, in the form of a standing lamp. This effort aimed to guide designers and design students in the precise and effective transformation of local culture. Innovation was done through materialization, observation and experimentation (IMOE). They were applied to cultural artifacts, structured across four levels, namely the inner, middle, outer, and experimental. The experimental element assumed a central role in the methodology. The inner level encompassed the meanings and symbols of the cultural artifact (Mamuli pattern), while the middle level involved its creative process. The outer level represented the physical appearance, including materials, colors, and ornaments. The experimental element involved the creative process of transforming the cultural artifact into a contemporary form. The experiment targeted designers and design students, facilitating the creation of contemporary products through a culturally-sensitive transformation, fostering innovations. Developed through an ethno-mathematical theory and experimental folding techniques, it generated experimental innovative product designs. It transformed Mamuli pattern from East Sumba woven fabric into Kandunnu standing lamp, drawing inspiration from both the outer and inner levels.
Contemporary Technologies for Promoting Safe Cities: The Case of Al-Salheya Compound in Iraq
Authors: Al-Hilli Amar Mohammed Abdulmajeed , Al-Alwan Hoda A. S.
Published: October 2023

After the events of 9/11, the world's perception of security in the cities has changed. Management and security have become an important issue of contemporary cities. In fact, almost all cities of the world seek to have their cities safe from terrorism, and threats of vice. To reach this goal, the contemporary cities use modern techniques and technologiesin various fields, installed by individuals, societies, as well as institutions. Installing security and civil technologies in public places and vital sites is one of the most important ways to improve safety, security, and civil control. The hardware, software, and qualified human element, with the presence of the latest auxiliary and supportive mechanisms, contribute significantly to achieving safety of the cities. The research examinessecurity technologies implemented in the Al-Salheya residential compound in Iraq to enhance safety of the city. It therefore carries out a comprehensive review of modern security technologies in contemporary cities. It employs a qualitative approach as a research methodology. Data is collected from surveys, observation, questionnaires and interviews. It concludes a variety of security and civil technologies at the levels of monitoring, verification, reaction, central database, and support technologies compatible with the needs of Al-Salheya compound in Iraq.
Analyzing Translation Strategy of Loneliness Song Lyric
Authors: Kriswesti Rhematra , Afifulloh M , Widyasari
Published: October 2023

The song Loneliness went viral after America's Got Talent gave it a Golden Buzzer for the performance of the song's owner, Putri Ariani. Behind the popularity of this song, there is a sad story that Putri experienced, such as being underestimated because of her physical limitations. In this case, a song lyric can have value and be able to attract attention if the choice of words is correct. As the function of lyrics and songs is to speak universally, they can express the contents of the creator's heart, and reflect the culture of various existing cultural diversity. Therefore, examining song lyrics can provide an academic narrative of the meaning contained therein. This research aims to explain the technique of translating English into Indonesian for the song Loneliness by Putri Arian. Using a theoretical approach to translation techniques from Newmark (1988) and Larson (1984), the song Loneliness was analyzed qualitative-descriptive. The results of research on the lyrics of the song Loneliness by Putri Ariani are the meaning of the song using adaptation techniques, semantic translation and the concept of lexical items.
AKTIVITAS DAKWAH MELALUI PROGRAM SHALAT DHUHA PADA SISWA JURUSAN MULTIMEDIA SEKOLAH MENENGAH KEJURUAN (SMK) AL-HUDA KEDUNGWUNGU ANJATAN INDRAMAYU
Authors: Taufikin Taufikin
Published: October 2023

The school environment is a very good place for da'wah activities. School is a place to instill values of character, religion and humanity. Da'wah activities in schools are interesting to study. This study discusses the process and effects of the Dhuha prayer for students majoring in Vocational High School multimedia at Al-Huda Kedungwungu Anjatan Indramayu Vocational High School. The qualitative approach is the research approach used by the author in this study. Based on the type of research, this research is included in field research. As for the technique of collecting data through the process of observation, interviews and documentation that comes from both sources and from related documents which are then analyzed and interpreted in a qualitative descriptive form. The results of the research show that there is a process of da'wah activities for Al-Huda Kedungwungu Anjatan Indramayu Vocational High School (SMK) Students. In addition to the teaching and learning process at Al-Huda Kedungwungu Anjatan Vocational High School, Indramayu also includes da'wah activities in it. Based on the field, the Al-Huda Vocational School programmed Dhuha prayers to be held at schools which were then revived with da'wah activities including Al-Qur'an study and lectures.
STRATEGI DAKWAH MELALUI LAGU MATI MASUK SURGA
Authors: Ghifari Irfan , Abdurrazaq Muhammad N. , Tebba Sudirman
Published: October 2023

Da'wah is one of the obligatory tasks for every Muslim, especially in conveying good messages. One of the da'wah activities that is commonly found is through a lecture activity. During the Sunan Kalijaga era, preaching was not only through lecture activities, but through an art that was already being performed by the general public on the island of Java. With the development of the times, many methods of da'wah are used, one of which is through music. Wali Band is a band that preaches through music. Of the many songs that have been composed, the Wali Band song which is used as the object of research is "Mati Masuk Surga". The purpose of this research is to find out the background of the creation of the song "Mati Masuk Surga" and the Wali Band's missionary strategy in the future. In this study, the authors used a qualitative research approach. In collecting data, researchers used observation techniques, interviews, and documentation. For data analysis techniques used through data analysis, data reduction, data presentation, and drawing conclusions. After analyzing the song "Mati Masuk Surga", research found that the song was created because during the pandemic many people used the TikTok application to entertain themselves. The strategy carried out by Wali Band in the future uses a sentimental approach (Al-Manhaj Al-Lathifi).