bluuebunny/crossref_metadata_2025 huggingface dataset:
Introduction. The Social Construction of the Anthropocene: Theoretical and Ethical Perspectives
Authors: Douglas Price Jorge Eduardo , Preite Gianpasquale
Published: February 2023

The ancient one-to-one relationship with the biological life cycle has gradually deteriorated due to the world undergoing a metamorphic process. Such a metamorphosis has affected ecological harmony, in terms of it being both an approach to studying the relationships between living beings and the environment, and a branch of knowledge protecting and promoting ecological balance. One of the crucial aspects of this phenomenon is the need to rethink and redefine the concept of life in an era that has been described as the “Anthropocene”. In introducing this special issue of the Journal, the paper aims to investigate the environmental question, which plays a crucial role in contemporary political thought, due to the survival of both nature and mankind being threatened. Since the 1950s, such a complex situation has resulted in two lines of thought whose views follow two opposed ideologies – anthropocentrism and anti-anthropocentrism.
Anthropocène et action politique : l’émergence d’un nouveau temps baroque
Authors: Roth Deubel André-Noël
Published: February 2023

The Anthropocene, as a geological and biological fact, is a baroque moment insofar as it is the meeting with an uncertain outcome between two irreconcilable truths. The truth hitherto considered as such, classic, is put in doubt by another truth, without this one being able to impose itself. The awareness of this confrontation, irreconcilable for the moment, favors in the human species a spectacular and rhetorical political action, that is to say baroque.
L’ambientalização dans les territoires de l’Amazonie brésilienne : entre production et engendrement
Authors: Teisserenc Pierre
Published: February 2023

The article uses research carried out on three Extractivist Reserves in the Brazilian Amazon to “test” the distinction proposed by Bruno Latour (Où atterrir ?) between territories of production and territories in begetting on which the social question challenges the environmental question in a context of ambientalizaçao (Leite Lopes, 2006). These analyzes are inspired by a grid proposed by Claude Lefort (Essais sur le Politique) to respond to the “challenges of the democratic revolution”.
Dal cosmopolitismo radicale al cosmopolitismo radicato. Intervista a Anthony Kwame Appiah
Authors: Taraborrelli Angela
Published: February 2023

Anthony Kwame Appiah is an internationally renowned philosopher who has worked on the philosophy of language, political and moral theory, African intellectual history and cosmopolitanism, with a particular interest in the theme of identity. He has held prominent positions and received numerous important awards; he has also dedicated himself to an intense activity of dissemination, giving countless lectures and collaborating with a number of newspapers, such as the BBC at which in 2016 he gave the Reith Lectures on the theme of identity and the New York Times Magazine where, as a columnist, he reasons about the ethical dilemmas that can arise in everyday life. In Italy he has published Cosmopolitismo. L’etica in un mondo di estranei (2007), Il codice d’onore. Come cambia la morale (2011), La menzogna dell’identità (2019). In this interview, given in July 2021, he explains his conception of cosmopolitanism, which he named “rooted or patriotic”, and from this perspective addresses the topics of migration, cosmopolitan education and practice, ‘cancel culture’ and freedom of expression.
Sentiment civique et anticivisme chez Simone Weil
Authors: Chenavier Robert
Published: February 2023

In our world, removed from all transcendence, the “freedom of the modern” triumphs. The criticism of a certain modernity in Simone Weil’s work does not imply the return to a praise of the value of citizenship as a virtue of the citizen who has the sense of his “duties towards society”. True, she never advocated “incivism”, which is an expression of individualism. However, she professed a form of “anticivism”, which implies a very different axiology from that of civism defined by society, which belongs to the “middle region of values”. That is why Antigone is the Weilian model of “anticivism”.
Virgilio Mura, o della serietà
Authors: Bovero Michelangelo
Published: February 2023

Passed away in the early summer of 2021, Virgilio Mura practiced political philosophy following the method of conceptual analysis, in the wake of the tradition generated by neo-empiricism and far from “analytical philosophy” that become dominant in the last half century. In Mura’s thought, seriousness as rigor in the application of the analytical method is combined with the defence of secularism, expressed in his stance in favour of a form of relativism that should not be confused with indifferentism.
Salvatore Veca: filosofo e intellettuale pubblico
Authors: Maffettone Sebastiano
Published: February 2023

The article aims at showing Salvatore Veca’s philosophical thought, from the classical figures of the beginnings of his reflection (in particular Kant and Marx), to his encounter with Rawls’ political philosophy and up to the recent developments. The author also emphasises the importance of Salvatore Veca as a philosopher tout court and public intellectual.
Governance models of Hungarian higher education: from Humboldtian to State-controlled model
Authors: Rodrigues Pimenta Carla Liege , Rónay Zoltán
Published: February 2023

The paper focuses on the higher education evolution in Hungary from the historical perspective regarding the governance models implemented and constructed in connection with the legal provision of decision-making power within universities, between various governance mechanisms (faculty, academic committees, senates, and boards) and administrative structures. We identified four governance models during the last hundred years. In the primary stage, we track down the Humboldt model, and the German influence played a role in the institutional development. The beginning of communist era represented a reform called “de-Humboldtization” and it was the beginning of the second phase in which the Hungarian higher education reform can be identified under the socialist influence, concentrating on the formation and organisation of the Soviet higher education institutions. The subsequent stage, the neo-Humboldtian type (1993-2012), can be identified as the regaining autonomy at the higher education underneath the shifting of communism regime to democracy and market economy. However, during this era, the government continuously tried to reform university governance, which touched every time the autonomy issue. Undoubtedly, many elements of these reforms caused a slow sink of the level of autonomy. Ten years ago, started the fourth period. First, the state-controlled model (chancellor and Consistory system) and now the pseudo-private model has been introduced. These last two models are linked with intensive decreasing institutional autonomy and academic freedom at Hungarian higher education and showed that the current legislation regulates the operational and financial issues of the institutions.
The The right to outdoor education at the beginning of the Twentieth century: reflections and practices from the pages of a Milanese journal (1911-1923)
Authors: Seveso Gabriella , Comerio Luca
Published: February 2023

In the early Twentieth century in Europe there was a very lively debate about the need for an outdoor education for boys and girls, linked to the more general sensitivity to the issue of the protection of children’s rights: many associations, movements, thinkers underlined, in fact, how boys and girls should have enjoyed the right to health, education and dignified growth. Among these, the Società Umanitaria (Humanitarian Society) in Milan stood out: it took an active part in the debate on teacher training and the reform of children’s institutions, playing a fundamental role in the propagation of the Montessori method; this institution also disseminated original reflections on the right to outdoor education and initiated innovative experiences centred on contact with the natural environment, both because this theme was a fundamental part of the Montessori proposal, and because more generally it responded to the ideals based on healthy life, on education in nature, and on the recovery of juvenile discomfort through contact with the natural environment. This contribution, therefore, aims to investigate the role played by the Società Umanitaria in promoting the right to outdoor education, analysing the issues of the magazine “La Coltura Popolare”, with a particular focus on the activities carried out to promote holiday camps and recreational facilities: this is a still unexplored research path, which brings to the attention of scholars a magazine that offered important spaces of exchange for the most innovative pedagogical experiments and the most stimulating reflections of the time.
Florence’s schools photographic heritages: themes and method of a work in progress research
Authors: Naldi Chiara
Published: February 2023

This contribution intends to define aims and methodologies of a research project on Florence’s school photographic heritages between Nineteenth and Twentieth century. The research is part of relevant national interest project on school memory and proposes a first and partial reconstruction of the significant role of photography in visual school memories. The research methodology intertwine History of Education with History of Photography and starts from the photographic objects found in the single schools to investigate the historical and pedagogical contests in relationship with their photographic representation. Focusing on three cases studies, the research project aims to investigate the different using of photography at school, it also exploring the specific visual culture developed between different approaches, experiments and views on students and teaching activity.
The question of education in the thought of Carlo Pisacane
Authors: Ferrari Giovannipaolo
Published: February 2023

The Italian Risorgimento left behind a series of figures and personalities that have become part of the mythopoiesis of a modern nation. An important role was played by the figure of Carlo Pisacane, who on many occasions was stripped of his philosophical-political stance to make way for the figure of the Risorgimento martyr or romantic passionate. We want here to follow in the footsteps of those who have paid particular attention to Pisacane’s political, philosophical and social thought, describing him as a precursor of socialism, anarchism and the idea of a republican Italy united in an assembly of communes. The purpose of this paper is to offer reflections on the problem of education in Pisacane, a subject that very few historians and biographers of Pisacane have addressed and that he himself treated only in passing, but to which he gave an important place in his work. Although he was not an educator or pedagogue, Pisacane attempted to sketch a model of national education because he felt it necessary to complete his description of the social order that would emerge from the new social pact and to emphasize the importance that would be given to education and the pedagogical function in the future organization of the masses.
Webster’s 1793 speller: not yet a portrait of America
Authors: Meirelles Virginia , Mitchell Linda , Revuelta Maria
Published: February 2023

The many different authors that have examined Webster’s speller agree on its influence in establishing American English. However, this examination seeks to accomplish something different from these works: to further explore the author’s linguistic and political concerns to reveal how they influenced the design of the speller. For that reason, this article compares Webster’s American Spelling Book of 1793 to Thomas Dilworth’s American edition of A New Guide to the English Tongue (1796). The essay identifies the changes that Webster introduces in his speller, set apart from Dilworth’s, and reveals how they were determined by his nationalistic beliefs and how the alterations might have contributed, from the author’s perspective, to the creation of a national character in the United States. Still, the investigation concludes that this edition of the speller does not, yet, define what it is to be American.
Historiography in contemporary Italy
Authors: Cambi Franco
Published: February 2023

The text traces the development of Italian historiographic research from the second post-war period to the present, establishing the innovative moments and the models that have gradually established themselves that have evolved and enriched. In particular, it was the 1960s and 1970s that developed this transformative trend and to which we are still indebted today, precisely because of the high quality that has characterized national historical research.
El Desarrollo Profesional Docente para el fortalecimiento de la competencia digital en prácticas pedagógicas en educación básica: Una revisión sistemática
Authors: Ramírez-Galindo Filemón , Bernal-Ballén Andrés
Published: February 2023

El desarrollo profesional docente como proceso que fortalece la competencia digital en las prácticas pedagógicas en educación básica es un asunto de gran importancia que requiere del trabajo y ejercitación cognitiva y emocional en el ámbito personal y colectivo. Aunque la literatura científica sobre este aspecto ha abordado con suficiente claridad las convicciones y creencias y la puesta en práctica de alternativas apropiadas de mejora por parte del docente, esta investigación pretende realizar una revisión sistemática de la literatura que hace referencia al desarrollo profesional docente enmarcado en el contexto de la competencia digital. La metodología planteada fue elaborada siguiendo los principios contenidos en la declaración PRISMA y se encuentra estructurada en dos fases: la primera establece la estrategia de búsqueda de los artículos relacionados con la temática y la segunda organiza, analiza y presenta los resultados más significativos de la revisión sistemática de la literatura. Los resultados obtenidos evidencian la necesidad de fortalecer los procesos de desarrollo profesional docente en cuanto a la competencia digital y el uso de recursos tecnológicos, así como la formulación de políticas educativas que incentiven mejorar en los docentes su nivel profesional.
Proceso de aprendizaje durante Covid-19. Percepción de universitarios en el área de agronomía
Authors: Montes de Oca Erika Román , Licea Resendiz Jesús Eduardo , Victorino Ramírez Liberio
Published: February 2023

El presente trabajo analiza cómo los estudiantes percibieron las principales problemáticas en el proceso de enseñanza y aprendizaje aplicado durante la pandemia por Covid-19, y cómo se fueron adaptando a esta nueva realidad al hacer uso de las Tecnologías de Información y Comunicación (TIC) en el desarrollo de las actividades contenidas en las unidades de aprendizaje, esto a partir del cierre de las instituciones educativas instruido por las autoridades correspondientes. El método de investigación fue de tipo cualitativo y cuantitativo. La muestra para el análisis fue del tipo por conveniencia, aplicando 145 encuestas y seis entrevistas a profundidad a estudiantes de dos carreras de la Facultad de Ciencias Agropecuarias de la Universidad Autónoma del Estado de Morelos, México. Se observaron problemáticas como la falta de interés por parte de los estudiantes para realizar las actividades académicas, el exceso de trabajos, entre otros problemas de tipo psicológico y económico, principalmente. Empero, se concluye que tanto estudiantes como docentes se esforzaron para poder cumplir con el programa de las asignaturas y no perder o reprogramar el ciclo o semestre escolar correspondientes.
Penerapan Search Engine Optimazation untuk Optimasi Performa Konten Pada Website Kampus
Authors: Triawan Anggra , Pujiantina Majid An Nissa
Published: February 2023

The use of content on the campus website that is still static, using a single meta tag, and not applying meta writing techniques causes the content on the website to be not optimal and the use of meta tags, headings and subheadings in website content is not yet effective, so optimization on page optimization is still weak. Search Engine Optimization (SEO) is a way to optimize a website so that it ranks at the top of search results. On Page Optimization is a technique for optimizing content on website pages. This study applies Search Engine Optimization On Page to optimize content on the Binaniaga Indonesia University website. The results of the measurements carried out for one week obtained the final result measurement of 3.59, the average number of persession pages from 5 users, with an increase of 41.78% after implementing Search Engine Optimization. So that the developed application can be categorized into a very feasible interpretation.
La dudosa ubicación en el sistema de fuentes del acuerdo de funcionarios
Authors: Santandreu Capón Francisco José
Published: February 2023

El artículo trata de la difícil ubicación de los acuerdos de funcionarios a la luz del artículo 38 del texto refundido del Estatuto del empleado público por suponer la posibilidad de inversión en el orden jerárquico en la pirámide normativa entre acuerdos de funcionarios y normas reglamentarias. Esta situación se aprovecha para hacer una indagación en la doctrina constitucional referida a la naturaleza de los convenios, pactos y acuerdos de funcionarios con el fin de establecer su concreta ubicación, que dependerá de las relaciones existentes ya no solo entre normas, sino entre los principios constitucionales de distribución de competencias y jerarquía.
Responsabilidad patrimonial por el impacto de la normativa COVID-19 en el ejercicio de las actividades económicas
Authors: Oreiro Romar José Ángel
Published: February 2023

Como consecuencia de la pandemia producida por el virus COVID 19, las Administraciones públicas han adoptado toda una serie de medidas legislativas para combatir las consecuencias del virus sobre la salud de los ciudadanos y sobre el funcionamiento del sistema sanitario público. Este trabajo analiza la viabilidad de las reclamaciones de responsabilidad patrimonial encaminadas a resarcir los perjuicios derivados del impacto de estas medidas sobre el ejercicio de actividades económicas y mercantiles.
Responsabilidad patrimonial y Covid
Authors: González-Varas Ibáñez Santiago
Published: February 2023

En este trabajo se estudia la responsabilidad patrimonial por daños como consecuencia de las medidas administrativas impuestas durante el COVID-19
Factors That Support The Completeness of Filling Out KIA Book (Mother and Child Health)
Authors: Ustriyaningsih Ustriyaningsih , Irene Kartasurya Martha , Sriatmi Ayun
Published: February 2023

The KIA Handbook is a manual that contains information sheets and records of health services for mothers and children. However, the use of the KIA handbook has not achieved maximum results because the documentation system is still done conventionally. This study aims to analyze and describe the input, planning, and organizing factors that affect the completeness of filling out the KIA handbook. This study uses a literature review method. Journal searches were obtained from the Google Scholar database using keywords and inclusion criteria. The steps of data analysis are: data collection, data reduction, data presentation, and conclusions. The article search results obtained 34 articles published in national online journals using the Google Scholar search engine with keywords and inclusion criteria, namely: time period, language, subject, type of article, and theme of article content. The conclusions in this study are: (1) The input factors that affect the completeness of filling out the KIA book from the midwife's side are knowledge, attitudes, skills, while from the mother's side, namely in terms of knowledge, (2) Planning factors that affect the completeness of filling out the KIA book are service SOPs. Antenatal care at the Puskesmas is made by the Puskesmas based on the integrated antenatal service guidelines set by the District Health Office, and (3) Organizing factors that affect the completeness of filling out the KIA handbook, namely cooperation and joint commitment by each part involved such as: Health Office, Head of Puskesmas, Implementing Midwives, Local Government (Districts), Pregnant Women's Families, and Employers
SURGICAL TREATMENT OF ACUTE SMALL BOWEL OBSTRUCTION: CLINICAL AND LABORATORY PARAMETERS ASSOCIATED WITH STRANGULATION AND EARLY MORTALITY AFTER SURGERY
Authors: Kryvoruchko Igor A. , Boyko Valeriy V. , Sartelli Massimo , Coccolini Federico , Catena Fausto , Olefir Olexander S.
Published: February 2023

The aim: The study aimed to evaluate some criteria for preoperative diagnosis of strangulation and significant indicators of the prognosis of short-term outcomes in patients with small bowel obstruction.
Materials and methods: The results of the treatment of 123 patients aged 18–70 years with SBO were evaluated.
Results: All of these patients underwent emergency surgery, and 22 patients (17.9%) have died. It has been shown that four lab parameters (blood leukocytes, lactate, intestinal fatty acid-binding protein, and C-reactive protein levels) and one instrumental (involving the mesentery of the small intestine, free fluid in the abdomen during CT) with 80% probability or more were associated with the strangulation type of SBO (Λ=0.276, p = 0.000). Three lab indicators (WBC count, serum lactate, and intestinal fatty acid-binding protein levels) and two clinical parameters (abdominal perfusion pressure level and the presence of abdominal sepsis) were associated with early mortality after surgery (Λ=0.626, p = 0.000) with the same probability. Immediate results of the treatment in these patients depended on the development of intra-abdominal complications after surgery (P = 0.024) and the need for early reoperation (P = 0.006) as well as the development of cardiovascular dysfunction (P = 0.000) and respiratory dysfunction (P = 0.000).
Conclusions: There were confirmed parameters that were significantly associated with strangulation before surgery and short-term in-hospital mortality with an 80% probability or more. This made it possible to develop new mathematical models for the diagnosis of strangulated bowel obstruction and early postoperative mortality with an accuracy of 84.5% and 84.2%, respectively.
OCCUPATIONAL SAFETY AND HYGIENE OF HEALTHCARE PROFESSIONALS IN THE CONTEXT OF HOSPITAL ENVIRONMENT SAFETY
Authors: Yavorovskyi Oleksandr P. , Brukhno Roman P. , Omelchuk Sergii T. , Skaletsky Yurii M. , Paustovskyi Yurii O. , Zenkina Valentyna I. , Zinchenko Tetyana O.
Published: February 2023

The aim: This study was conducted to carry out a comprehensive assessment of the occupational safety and health of medical workers.
Materials and methods: The study involved a questionnaire survey and full-scale physiological and hygienic research using bibliosemantic, questionnaire, hygienic, and statistical methods.
Results: In the course of research it was recorded that the work of surgeons (according to the criteria of the current “Hygienic classification of work”) is characterized by high intensity (class 3.2), high probability of exposure to infectious agents (class 3.3, and 4), harmful effects of physical factors (class 3.1 ), which according to the criteria of the general hygienic assessment of working conditions according to the degree of harmfulness and danger allows being assigned to class 3.3 (“harmful”) and 4 (“dangerous”), respectively. Such working conditions provoke an increase in chronic morbidity (industrial and temporary disability), lead to the development of occupational diseases, and can pose a threat to the lives of workers. The need to focus attention on assessing the safety of hospitals in emergencies not only on issues of occupational safety and health but also on the stability and reliability of hospitals in such extreme conditions.
Conclusions: The work process of doctors is characterized by the impact on their body of a complex of unfavorable production factors of psycho-physiological, biological, physical, and chemical nature, among which the leaders are high labor intensity due to intellectual and emotional load, irrational mode of work and rest, and biological factors.
THE NEUROPROTECTIVE EFFECT OF TOCILIZUMAB IN BRAIN ISCHEMIA REPERFUSION INJURY
Authors: Assad Rashid Muhssen , Al Mudhafar Ahmed M , Hadi Najah R.
Published: February 2023

The aim: This research was conducted to assess the possible neuroprotective effect of Tocilizumab in brain ischemic reperfusion injury in rats.
Materials and methods: 24 adult Sprague-Dawley rats were divided into four groups randomly. The sham group was given anesthesia at the same time as the other groups and was in the same condition as the other groups. Control group: 1 h of ischemia followed by 4 h of reperfusion. The vehicle group was the same as the control, but they were given the vehicle intraperitoneally (1 ml/kg of 0.9 % NaCl) for 7 days before the ischemia. The treatment group as the control group, but they were given tocilizumab (8 mg/ kg) intraperitoneally for 7 days before ischemia.
Results: control group, inducing ischemia/reperfusion increased infarction size considerably (p<0.001), when comparison to the control and vehicle groups, tocilizumab at dose (8 mg/kg) showed a significantly (p<0.001) smaller infraction area.
Conclusions: In a cerebral ischemia/reperfusion, a reduction in infarction area in injected with Tocilizumab medication was considered neuroprotective for cerebral ischemia/reperfusion.
EVALUATION OF HUMAN ABO BLOOD GROUPS AND BLOOD COMPONENTS AMONG IRAQI PATIENTS INFECTED WITH CORONAVIRUS DISEASE 2019 (COVID-19)
Authors: Ghafil Nagham Yahya , Bairam Ahsan Falah , Kadhim Zahraa Jawad , Alkaabi Yarob Saad Abdiljaleel
Published: February 2023

The aim: To evaluate the differences in blood groups, gender and type of Rh factor, as well as the levels of hemoglobin, white blood cells and platelets among patients infected with COVID-19.
Materials and methods: A cross-sectional study was performed on 202 patients diagnosed with sever COVID-19 infection who were admitted to the Al-Shefaa center in Al- Hakeem hospital in Al-Najef city.Haematological investigations involved the types of blood groups, Rh factors, haemoglobin (Hb), white blood cells (WBCs), and platelets. In addition, the demographic features including age, gender and presence of any prescribed medications before or at the time of the study were also included.
Results: This study indicated that COVID–19 infected patients with type A blood group are at higher risk of hospitalization than other blood groups, and the majority of these patients were Rh positive. Additionally, WBCs counts indicated that the majority of patients had increased risk of getting infections which demonstrated lower WBC counts than normal. Platelet and Hb levels were normal for the majority of patients.
Conclusions: The findings of this study may help in the diagnosis of the pandemic infection with COVID-19, and prediction of the incidence of some complications caused by COVID-19. Further researches are warranted to confirm our findings.
GUT MICROBIOTA COMPOSITION AND ITS METABOLITES CHANGES IN PATIENTS WITH ATHEROSCLEROSIS AND ATRIAL FIBRILLATION
Authors: Melnychuk Iryna , Lizogub Viktor G.
Published: February 2023

The aim: To check changes of gut microbiota composition and its metabolites in atherosclerosis (AS) patients with or without atrial fibrillation (AF) and special connections between them and important clinic and laboratory features of investigated groups.
Materials and methods: 300 patients were investigated. All investigated were divided into 3 groups: control group (CG) – 27 patients without AS and arrhythmias; mean group – 149 patients with AS but without arrhythmias; comparable group – 124 patients with AS and AF paroxysm. By 16-S rRNA sequencing was checked gut microbiota composition. The level of trimethylamine-N-oxide (TMAO), trimethylamine (TMA) plasma was determined by gas chromatography with mass electron detection.
Results: The mean and comparable groups have the significant abundance of total bacterial mass, Bacteroides Spp., Faecalibacterium Prausnitzii, Actinobacter Spp. and decreas¬ing Ruminococcus Spp. In the comparable group to the mean significant increasing of Actinobacter Spp. and decreasing Eubacterium Rectale, Ruminococcus Spp. were checked. Bacteroides Fragilis Group/ Faecalibacterium Prausnitzii ratio was significantly higher than in patients’ comparable group. In the mean group patients compared with CG significant abundance of Streptococcus Spp. was checked. In the comparable group compared with CG significant leak of Eubacterium Rectale was checked. The highest amount of correlations was between Lactobacillus Spp., Streptococcus Spp. and clinic-laboratory changes. The mean and comparable groups the significant increasing of TMA ta TMAO plasma levels were checked. In patients of comparable group compared with patients mean group the significant increasing of TMAO plasma level was revealed.
Conclusions: We checked special bacterial changes of gut microbiota that are common for patients with AS and AF comparable with AS patients. TMAO plasma levels are increased significantly for patients with AS and AF comparable with AS patients. Connections between AS and AF with TMAO plasma levels are confirmed by reliable correlations between TMAO and age, BMI, GFR, HDL levels. Special bacterial species are closely connected with age, BMI, GFR, HDL, LDL, plasma TMA and TMAO levels.
THE RISK OF ACUTE KIDNEY INJURY AFTER ELECTIVE VERSUS EMERGENCY CORONARY INTERVENTION
Authors: Al-Mosawi Mohammed , Mousa Bashar Abed , Almohana Sadiq , Hadi Najah R.
Published: February 2023

The aim: A serious and common complication after percutaneous coronary intervention is acute kidney injury, which is associated with an increased risk of renal, cardiovascular and even mortality; therefore, early prognosis and identification of patients at higher risk are essential for early initiation of preventive measures. The aim of this study is to predict and compare the risk for the development of CI-AKI in patient with ACS who undergo emergency PCI or elective (i.e. after medical stabilization) PCI by utilizing the sensitivity of serum NGAL as an early and reliable predictor for CI-AK.
Materials and methods: The study include 37 patients with acute coronary syndrome, baseline serum creatinine, complete blood count and pre and two hours post operative serum neutrophil gelatinase-associated lipocalin were measured and all patients underwent percutaneous coronary intervention according to the standard protocol used in Al Najaf Cardiac Center.
Results: This is a Two-Arm study that included a total of 37 patients with acute coronary syndrome aged 38-83 years. Eighteen of them had emergency percutaneous coronary intervention while the remaining 19 had elective percutaneous coronary intervention (after medical stabilization). Elevation of serum neutrophil gelatinase-associated lipocalin level two hours after percutaneous coronary intervention was found to be significantly higher among emergency percutaneous coronary intervention group compared to elective group.
Conclusions: Acute coronary syndrome patients are undergoing emergency percutaneous coronary intervention are at an increasing risk for the development of contrast induced acute kidney injury than those undergoing elective percutaneous coronary intervention.
PROGNOSTIC ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN THE CARDIOVASCULAR COMPLICATIONS DEVELOPMENT IN PATIENTS WITH POLYMORBID PATHOLOGY: THE COMBINED COURSE OF HYPERTENSION, TYPE 2 DIABETES MELLITUS AND SUBCLINICAL HYPOTHYROIDISM
Authors: Nemtsova Valeriya D. , Vysotska Olena V. , Strashnenko Hanna M. , Borodkina Hanna M. , Utytskykh Tetiana O. , Balym Yurii P.
Published: February 2023

The aim: To determine the prognostic value of vascular endothelial growth factor (VEGF) levels for the development of cardiovascular complications in patients with a combined course of hypertension, type 2 diabetes mellitus and subclinical hypothyroidism.
Materials and methods: 93 patients (mean age 61,71±0,87 years) with the combined course of hypertension, type 2 diabetes mellitus and subclinical hypothyroidism were examined. Parameters of lipid, carbohydrate metabolism, plasma insulin, VEGF (by ELISA), blood pressure levels were measured. Observation period was12 months.
Results: VEGF levels in the patients group were significantly higher than in the controls (482,77±21,34 pg/ ml vs. 121,84±11,66 pg/ ml, p <0,001). The results of the ROC analysis made it possible to propose the level of VEGF ≥ 512.31 pg/ml as an identifier for the cardiovascular complications development in patients with studied comorbidity. VEGF levels in patients who developed cardiovascular complications during observation period were significantly higher the VEGF threshold levels (650,76 ± 52,04 pg / ml vs. 512,31 pg/ml, respectively, p = 0,038) and VEGF levels in patients without cardiovascular complications were significantly lower the threshold values (420,47± 21,67 pg/ml vs. 512,31 pg/ml, respectively, p = 0,047).
Conclusions: Determination of the vascular endothelial growth factor plasma level allows to evaluate the long-term prognosis in comorbid course of hypertension, type 2 diabetes mellitus and subclinical hypothyroidism.
THE VALUE OF SERUM SEROMUCOID IN THE DIFFERENTIAL DIAGNOSIS OF BACTERIAL PNEUMONIA AND TUBERCULOSIS IN HIV-POSITIVE PATIENTS
Authors: Tsyko Olena V. , Kozko Volodymyr M. , Yurko Kateryna V. , Solomennyk Ganna O. , Mohylenets Olena I. , Merkulova Nina F.
Published: February 2023

The aim: To optimize the differential diagnosis of bacterial pneumonia and tuberculosis in HIV-positive patients based on the value of serum seromucoid.
Materials and methods: The study included 77 HIV-positive patients with lung pathology. The 1st group consisted of 44 HIV-infected patients with BP; the 2nd group – of 33 patients with HIV/TB co-infection. Level of SSM, CD4+ T-lymphocytes, HIV-1 RNA viral load was determined. Сlinical, laboratory, microscopic, radiological, microbiological, and statistical methods were used in the research.
Results: In patients with HIV/TB co-infection CD4+ T-lymphocyte level was lower, and viral load was higher than in HIV-infected patients with BP. The level of SSM was statistically significantly elevated in patients of both groups compared with the control (p<0,001), but in patients with HIV/TB co-infection the values were statistically significantly higher (p<0,001). In patients with BP, the content of SSM≤15,95 TU occurred statistically significantly more often than in patients with TB (χ2= 65,5; p <0,001). No statistically significant relationship between SSM content and CD4+ T-lymphocyte levels was found.
Conclusions: The content of SSM in patients with HIV/TB co-infection is statistically significantly higher than in the group of HIV-infected patients with BP. Determination of SSM level can be used as a rapid method of differential diagnosis of BP and TB in HIV-positive patients that will allow to optimize the diagnostic algorithm at the early stage of hospitalization and to receive the necessary timely treatment for HIV-infected patients.
FEATURES OF THE FEMORAL HEAD FRACTURES COMBINED WITH ACETABULUM POSTERIOR WALL FRACTURES SURGICAL TREATMENT
Authors: Ankin Mykola L. , Petryk Taras M. , Zazirnyi Igor M. , Ladyka Viktoria A. , Barylovych Mykola M. , Fedoniuk Larysa Y. , Кerechanyn Іryna V.
Published: February 2023

The aim: To conduct a thorough analysis of the surgical approach features in femoral head fractures combined with acetabulum posterior wall fractures; to analyze these patients’ treatment results 12-36 months after the surgery; to determine the criteria affecting the satisfactory treatment results achievement in these injuries.
Materials and methods: The surgical treatment results were evaluated 13 and 36 months after the surgery. The retrospective analysis included 21 patients (17 men and 4 women) with femoral head fractures combined with the acetabulum posterior wall fractures. Pipkin and Brumback classifications were used to classify the fractures.
Results: The results of acetabulum posterior wall fractures delayed treatment are significantly different to the ones treated with early osteosynthesis. The reasons for that are difficulties in anatomical repositioning, femoral head malnutrition due to its displacement or chronic subluxation, reduced blood supply to the fragments due to surgical manipulations during the approach. Thus, according to Matta criteria anatomical reposition of the fragments was achieved in 19 (90.5%) cases, imperfect reposition in 1 (4.8%) case, unsatisfactory reposition - in 1 (4.8%) patient. The treatment results’ improvement after 3 years occurred due to hip joint replacement in 5 (23.8%) patients.
Conclusions: The treatment results of femoral head fractures with acetabulum posterior wall fractures depends on the type of fracture, concomitant injuries, the timing, and method of removing the femoral head dislocation, and the surgical treatment method.
EFFECTS OF ALPHA-LIPOIC ACID ON GLYCEMIC STATUS IN 2 TYPE DIABETES PATIENTS WITH СHRONIC CORONARY SYNDROME
Authors: Altunina Nataliia , Bondarchuk Oleksandr
Published: February 2023

The aim: To study the possibilities of alpha-lipoic acid (ALA) to control the parameters of carbohydrate metabolism.
Materials and methods: We examined 80 people with type 2 DM and coronary heart disease who suffered non-Q-myocardial infarction (non-Q-MI). All patients at the time of inclusion in the study received oral hypoglycemic agents, ACE inhibitor, β-blocker, statin and antiplatelet agent. 600 mg of ALA per day for 4 months was added to this treatment. After checking the patients for compliance with the criteria, they were divided into the main and experimental groups. The dosage of alpha-lipoic acid was determined for each of the groups. The results of the treatment were analyzed by determining the mean and standard deviations.
Results: At the end of the observation period, a significant decrease in the level of fasting glucose (FG) by 11.6% was found, which corresponded to the average size of the clinical effect. The values of glycosylated hemoglobin (HbA1c) and the insulin resistance index HOMA (HOMA-IR) showed only a tendency to decrease on the background of treatment. The effect of ALA on postprandial glycemia (PPG) and insulin levels was not detected in this study.
Conclusions: An additional 4-month dose of ALA in addition to baseline therapy showed a moderate effect on the decrease in FG concentration in the absence of significant dynamics in other parameters of glycemic control in the examined patients.
PREDICTING THE OCCURRENCE OF PRIMARY OPEN-ANGLE GLAUCOMA DEPENDING ON THE GENETIC POLYMORPHISM ENDOTHELIAL NO SYNTHASE (NOS3) GENE
Authors: Isaiev Oleksii , Serdiuk Valerii , Ziablitsev Denys
Published: February 2023

The aim: To develop the model for predicting primary open – angle glaucoma (POAG) depending on the presence of the genetic polymorphism in the endothelial NO-synthase (NOS3) gene.
Materials and methods: The results of genotyping 153 patients (153 eyes) with POAG are included in this investigation. 47 patients were in the control group. Their age was 65,0±13,1 years, duration of disease – 4,9±5,3 years. The polymerase chain reaction was carried out in the patients’ blood in the real time mode (Gene Amp® PCR System 7500 amplifier; USA) with the help of the TaqMan Mutation Detection Assays Life-Technology test system (USA). The program Statistica 10 (StatSoft, Inc., USA) was used for mathematical testing of the obtained results.
Results: The regression analysis confirmed the effect of rs1799983 and rs2070744 polymorphisms of the NOS3 gene on the development of POAG. Calculating their specific gravity based on the degree of the impact on the probability of developing the disease showed that rs2070744 – 72.2% had the greater impact than rs1799983 – 38.5%. The regression model of POAG risk depending on the genotypes of the NOS3 gene rs1799983 and rs2070744 polymorphisms was constructed with the satisfactory quality of mathematical prediction (-2log=202.59; χ2=28.91; P<0.001). The value of probability of developing POAG exceeded the limit value (Cut-off=0.8), respectively, OR 4.39 (95% CI 1.00-19.30; P=0.048) and OR 14.15 (95% CI 1.88-106.28; P<0.001) in carriers of the rs1799983 and rs2070744 GT-CC and TT-CC haplotypes.
Conclusions: The results of the study proved the importance of risk genotypes (TT rs1799983 and CC rs 2070744) for the development of POAG in patients from the Ukrainian population. It has been shown that the significant increase in the risk of POAG exists for carriers of the GT-CC and TT-CC haplotypes.
MORPHOLOGICAL PECULIARITIES OF THE PANCREAS OF MALE RATS AFTER PROLONGED ADMINISTRATION OF MONOSODIUM GLUTAMATE DURING THE RECOVERY PERIOD
Authors: Litvak Yulia V. , Harapko Tetiana , Lytvak Vasil , Foros Anatolii I.
Published: February 2023

The aim: To study changes in the exocrine and endocrine parts of the pancreas of rats after abolition of monosodium glutamate (MSG) administered in the diet.
Materials and methods: White male laboratory rats with a baseline weight of 120 ± 5 g were randomized into 3 groups: 1 – control, 2 – animals with daily feeding of 70 mg/ kg MSG for 8 weeks, 3 – abolition of MSG with transfer of animals to a standard diet and pancreatic examination after 8 weeks. We used histological studies with morphometric analysis and statistical processing of acini and acinar cell areas, Langerhans islets, connective tissue (according to Stolte M.) and adipose tissue. Preparations of pancreas were stained with hematoxylin and eosin and azan.
Results: The animals of groups 2 and 3 showed atrophic, degenerative and inflammatory disturbances in the exocrine and endocrine parts of the pancreas, which worsened after 8 weeks of MSG withdrawal (3 rd group). In the preparations, the Langerhans islets were of different shapes and sizes. Small islets predominated, as well as islets with low density of α- and β-cells, different capillary filling with blood and overgrowth of connective tissue in the capillary areas. The acinar cells and acini were reduced, and degenerative abnormalities were detected in the structures.
Conclusions: After daily administration of 70 mg/kg MSG for 8 weeks, atrophic and degenerative changes in the exocrine and endocrine parts of the pancreas were revealed. No recovery of pancreatic structures was observed 8 weeks after MSG withdrawal.
MAŞINQAYIRMADA MƏMULATLARIN KEYFİYYƏTİNİN İDARƏ EDİLMƏSİ
Authors: Ləman Əskərova, Rafiq Hacıyev Ləman Əskərova, Rafiq Hacıyev , Samirə Maliyeva, Sevinc Baxşəliyeva Samirə Maliyeva, Sevinc Baxşəliyeva , Şəmkir Zəkəriyəyev Şəmkir Zəkəriyəyev
Published: February 2023

Müasir dövrdə malların yüksək keyfiyyətinin müəssisənin uğurunda həlledici amil olması getdikcə aydınlaşır. Bu prinsipə riayət etmək ölkənin qlobal rəqabət qabiliyyətinə nail olmaq və onun həyat keyfiyyətini təmin etmək üçün ən mühüm şərtlərdən biridir. Yerli maşınqayırma müəssisələrinin məhsullarının yüksək keyfiyyətinin təmin edilməsi probleminin həlli zərurəti elmi-texniki tərəqqinin əsas elementidir. Bundan əlavə, keyfiyyət məsələlərinin həlli satış bazarının davamlı olaraq genişlənməsinə və mənfəətin artmasına, eləcə də müştəri tələbinin ödənilməsinə kömək edir. Ona görə də bu gün bu məsələ xüsusi əhəmiyyət kəsb edir. İstehsalın bütün digər sahələrində və qeyri-istehsal fəaliyyət sahələrində mütərəqqi dəyişikliklər əsasən maşınqayırma sənayesinin məhsullarının keyfiyyətindən asılıdır. Məhsulun keyfiyyət səviyyəsi həm xarici, həm də yerli müəssisələr üçün ən mühüm prioritetlərdən biridir. Bu baxımdan məhsulun keyfiyyətinin qiymətləndirilməsi üsullarının, onların formalaşma xüsusiyyətlərinin, idarə edilməsinin, səviyyəsinin təhlili üsullarının, habelə təşkilatlar üçün əhəmiyyətinin öyrənilməsi həm nəzəri, həm də praktiki baxımdan aktualdır. Həmçinin məhsulun keyfiyyətinin formalaşması prosesləri müəyyən qanunlara tabedir. Beləliklə, maşınqayırma müəssisələri tərəfindən məhsulun keyfiyyəti problemlərinin getdikcə artan aktuallığı, onların səviyyəsinin təmin edilməsinin nəzəri və praktiki əsaslarının öyrənilməsi bu işin mövzusunun, məqsədlərinin, vəzifələrinin, əsaslandırılmasının və strukturunun seçilməsini müəyyən edir.
Açar sözlər: maşınqayırma, idarəetmə, məhsulun keyfiyyəti, nəzarət, istehsal
NEFTQAZÇIXARMA SİSTEMİNDƏ HAVA KOMPRESSORLARININ SƏMƏRƏLİLİYİNİN ARTIRILMASI
Authors: Əlövsət Bağırov, Elmir Qocayev Əlövsət Bağırov, Elmir Qocayev
Published: February 2023

Məqalə neftqazçıxarma sistemlərində istismar olunan hava kompressorların texnoloji parametrlərinin təhlilinə, onların məhsuldarlığının və ümumi səmərəliliyinin artırılması məsələlərinə həsr olunub.
Müxtəlif neftqazçıxarma müəssisələrindəki hava kompressorlarının tam çeşidi və tətbiq sahələri üzrə təhlili nəticəsində kompressor parkının effektivliyini azaldan amillər müəyyən edilmiş, prioritet təşkil edən faktorlar daha dərindən öyrənilmişdir. Kompressorların məhsuldarlığına mənfi təsir edən əsas amil kimi havanın bilavasitə sıxılmasını təmin edən və boz çuqundan hazırlanmış silindr, piston və piston həlqələrin qarşılıqlı şəkildə sürtünmə nəticəsində yeyilməsi müəyyən edilmişdir.
Baş verən yeyilməni aradan qaldırmaq üçün çuqun piston həlqələrinin F4K20 markalı qeyri-metal ftorlon materialından hazırlanmıs həlqələrlə əvəzlənməsi məqsədəuyğun hesab edilmişdir.
Ftorlon həlqələrinin tətbiqi nəticəsində 2SQ-50 tipli kompressorlarının məhsuldarlığının 20-30% artacağı, elektrik enerji, ehtiyat hissələri və təmir xərclərinin azalacağı göstərilmişdir.
Açar sözlər: hava kompressoru, məhsuldarlıq, silindr, piston həlqələri, ftorlon.
The Application of CHSE in Cook Interpreter Activities at Sibayak International Hotel Berastagi
Authors: Zaitun Zaitun , Hutomo Ngger Putro Cahyo
Published: February 2023

The Ministry of Tourism and Creative Economy is currently implementing CHSE-based health protocols (Cleanliness, Health, Safety and Environment Sustainability) on tourism and creative economy efforts, to revive the sector from the downturn caused by the Covid-19 pandemic. The key to successful tourism in order to rebound immediately is the implementation of CHSE-based health protocols well and disciplined in each destination and tourism sector actors. Berastagi city is one of the tourist cities that is a mainstay of tourism in north Sumatra. This is certainly very related to the implementation of the CHSE program from the government, in order to make tourism activities in Berastagi city bounce back. The purpose of this research is to find out how to understand and apply the CHSE program to employees working in the kitchen department at Sibayak International hotel so as to have a positive impact from the application and can increase the trust of guests to stay. This research is descriptive research with data analysis method is qualitative descriptive. The results of the study can be concluded that cooks get a good understanding of the CHSE program that is being implemented by the government as an effort to prevent the transmission of the covid.19 virus, especially in the kitchen area as the place most at risk of becoming a medium of transmission of bacteria and viruses from humans to processed foods. The implementation of CHSE program in Sibayak Berastagi hotel kitchen goes well so it is expected that it will also have a good influence on the level of trust of guests not to worry about visiting and staying at Sibayak Berastagi hotel.