bluuebunny/crossref_metadata_2025 huggingface dataset:
MODERN GAME WITH THE NORM: LANGUAGE SPACE OF UKRAINIAN POETRY OF THE END OF THE 20TH AND THE BEGINNING OF THE 21ST CENTURY
Authors: MAKARETS Iuliia
Published: May 2022

The article tries to analyze the linguistic space of the Ukrainian poetry of the end of the 20th and the beginning of the 21st century. Its purpose is to trace tendencies in the language behavior of the Ukrainian poets of the period, especially in the treatment of the language norm. The new cultural situation caused mixing in texts of linguistic features of different social groups. Poetry, which used to be the sphere of refined language, now is filled with abnormal and deviant units.
Kitsch, chaos, and destruction, which guided the poets of this period, are manifested in the destruction of the norms of literary language. Language deviation is the organic part of the poetic space of the period, one of the means of realizing its multilevel nature. On the one hand, it serves to homogenize, reconcile, and address the mass reader in their language, while on the other hand it is an instrument of irony and additional expression for the intellectual reader. The combination of high and mass cultures leads to the penetration of vernacular, surzhyk, obscene, and slang vocabulary in poetry, to the deconstruction of basic linguistic units.
The research proves: the destruction of the generally accepted literary standard, the diffusion of language codes, the collage of stylistically heterogeneous language signs, the deconstruction of words have become part of the language game, an an organic component of the poets’ language behaviour, in which deviation becomes the new norm.
THE ROLE OF THE MUSICAL HEARING IN THE FORMATION
OF PHONETIC AND PHONOLOGICAL COMPETENCE
Authors: POPOVA Marianna V. , TOKMAKOVA Ksenia M.
Published: May 2022

The main objective of the study was to determine whether the musical hearing may be considered among factors affecting the degree of a foreign accent in a second language (L2) and how important it is mastering the perceptual and productive aspects of the suprasegmental level of foreign languages by students of linguistics specializations. The results of the study showed that subjects with developed musical hearing performed tasks on both aspects perceptual and productive more successfully. However, there are reasons to assume that the significance degree of the influence of a developed musical hearing on both the perceptual and productive aspects may differ depending on a range of other factors. Therefore, further research aimed at establishing the role of musical hearing in the hierarchy of the factors affecting the development of the phonetic and phonological competence is of great importance. The obtained results might contribute to finding new original forms and methods of teaching phonetics of foreign languages based on musical art, as well as to improving the efficiency of mastering the phonetic-phonological competence by students of linguistics majors, and to creating auxiliary programs aimed at the developing of musical, and, consequently, phonetic hearing.
FROM INTERFERENCE IN THE TURKISH LITERARY LANGUAGE TO A TOTAL BAN
(THE LANGUAGE POLICY OF COMMUNIST BULGARIA)
Authors: HACI Sadık
Published: May 2022

Although in some periods of communist Bulgaria there was a weakening of the pressure and control over the education, language, culture and literature of the Turks in the country, the assimilation policy was always on the agenda of the totalitarian authorities. Various means of control over the education and the press were used, and after the April Plenum the authorities gradually proceeded to deform the Turkish literary language by forcing the introduction of Bulgarian vocabulary and the violation of its grammatical construction, punctuation, transcription. A special list of words which had to be used in print and literature was created. This rude intervention was supported by the publication of materials in Bulgarian, which were progressively increasing. The publication of Turkish literature was stopped, and writers either had to start writing in Bulgarian or remain silent forever. The linguistic policy of the totalitarian state against the Turkish minority in the second half of the 1980s reached its highest degree, resulting in a total ban on the Turkish language not only in its written form, but even its use in a home environment.
This study aims at presenting a previously unexplored problem of the direct encroachment on Turkish literary language and the destruction of already published literature.
A Statistical Investigation of Variables on Government Economic Policy Choices, Business Environments and Prices
Authors: Todo Charles Oghenekparobor , Obisue Edwin Ikechukwu
Published: May 2022

Does government economic policy choices have effects on businesses and/or prices? Do they relate in some way? This is the issue the paper seeks to address. We collected data on government economic policy choices, businesses environments and prices from countries in Africa, Asia, America and Europe. The data were subjected to statistical investigation by calculating six correlation coefficients for each continent, ascertaining which variables are correlated, and getting the levels of correlations. The results empirically show that in three continents, government economic policy choices do have effects on the business environment. The continents are Africa (correlation between Govt. Debt to GDP growth and Corruption Index is 0.504488), Asia (0.488973), and America (0.515489). They are all in the same range. The correlation coefficient for Europe is very low (0.016655).
Investigating Factors to be Considered for Successful STEM Integration Education in Ghana
Authors: Takyi-Bondzie John , Asiedu-Addo Samuel Kwesi , Saah Jemima
Published: May 2022

The purpose of the study was to investigate into the main factors to consider for successful STEM integration education as Ghana decides to incorporate STEM education into its educational curriculum. The study used concurrent mixed method as the study design and purposive and snowball sampling to sample thirteen (13) stakeholders for the study. The instruments used for the data collection were questionnaire items for the quantitative part and a semi-structured interview for the qualitative part. All thirteen respondents answered the questionnaire whereas 12 respondents availed themselves for the interview. The data gathered were analysed separately yet concurrently. The findings reveal that for a successful STEM education in Ghana there is a need to look at capacity building of teachers which is paramount, interest of students, etc. The study recommends that the Ghana Education Service must ensure that well qualified STEM teachers are recruited into our schools. Heads of institutions must ensure there is continuous professional development of their teachers.
Sistem Pakar untuk Klasifikiasi dan Diagnosa Penyakit Burung Murai Batu Menggunakan Metode Dempster-Shafer
Authors: Rifki fahrial zainal  , Syariful Alim  , Muhammad Hamza Syaiful Islam
Published: May 2022

Burung murai batu adalah anggota keluarga Turdidae. Burung keluarga Turdidae dikenal memiliki kemampuan berkicau yang baik dengan suara merdu, bermelodi, dan sangat bervariasi. burung ini juga mempunyai harga yang cukup mahal oleh sebab itu kebutuhan informasi sangat di butuhkan para masyarakat awam untuk mengatasi masalah tentang penyakit burung Murai Batu yang hanya bisa diselesaikan dengan bantuan para ahli. Dempster-Shafer adalah generalisasi dari Bayesian theory of subjective probability. Fungsi kepercayaan berbasis derajat kepercayaan (atau keyakinan, atau jaminan) pada suatu masalah terhadap probabilitas untuk masalah terkait. Derajat kepercayaan itu sendiri mungkin atau mungkin tidak memiliki sifat probabilitas matematika; seberapa banyak perbedaannya tergantung pada seberapa dekat kedua permasalahan itu berkaitan.

Pada penelitian ini menghasilkan sebuah aplikasi sistem pakar untuk klasifikasi dan diagnosa penyakit pada burung murai batu menggunakan metode Dempster Shafer. Dalam aplikasi ini juga dapat digunakan untuk mencari presentase kemungkinan penyakit dengan mendiagnosa gejala yang tampak pada burung murai batu. Diharapkan dengan penggunaan aplikasi ini dapat menghasilkan diagnosa yang valid.
First record of Trichosea ludifica (Linnaeus) from Kazakhstan with notes on its bionomics (Lepidoptera: Noctuidae: Pantheinae: Pantheini)
Authors: Titov Sergey V. , Volynkin Anton V.
Published: May 2022

Trichosea ludifica (Linnaeus, 1758) is reported from Kazakhstan (East Kazakhstan Region, West Altai Mountains) for the first time. The species habitat in Kazakhstan is briefly characterized and illustrated. A list of noctuid moths occurring syntopically with T. ludifica is also provided.
Realizing Fee-Free Higher Education in South Africa; Dreams and Nightmares
Authors: Sefoka Isaiah Mmatipe
Published: May 2022

The component of free rudimentary education is guaranteed and recognized by the 1996 Constitution, the African National Congress (ANC) Freedom Charter as well as other international instruments such as the Universal Declaration of Human Rights (UDHR) and the International Covenant on Economic, Social and Cultural Rights (ICESCR). Conversely that there exists no component of free higher education in South African laws and statutory guidelines, let alone in the international arena advocating for free higher education. Notwithstanding this fact, reality has shown that free higher education has not been realized despite students’ petition which fact has instigated them to take part in severe dissents from the four walls of South Africa. This paper argues that free higher education is not realizable the South African government has limited resources and the economy is on its knees. The paper further argues that for the South African government to fund free higher education it needs a well-resourced economy which is the contrary in South Africa.
The Impact of Online Learning on Students’ Achievements
Authors: El Malaki Fatima Zahra , Kroum Fatima Zohra
Published: May 2022

The current research tends to investigate the effect of online learning on students’ achievement and performance in classrooms. The pandemic has disrupted teaching and learning system around the world, in general, and Morocco in particular. Electronic learning (e-learning) has become the core method of teaching curriculum during the lockdown. This paper investigates the impact of online learning on students’ achievement during the lockdown; Moroccan vocational institutions as a case study.  This research attempts to shed light on the perceptions and attitudes toward students’ experiences regarding online learning, capacity to assimilate information, targeted skills, and the use of e-learning platforms. The paper also discusses some key challenges of online teaching for instructors and teachers followed by a discussion of the results to enhance the effectiveness of online learning.
The Impact of Gender on English Professors’ Use of Computer Technologies in Moroccan Universities
Authors: Laabidi Hicham , Laabidi Youssouf
Published: May 2022

To prepare students to face the challenges of the twenty-first century, teachers should integrate computer technologies into their teaching practices. These modern technologies are very beneficial for both teachers and students. They help teachers develop professional through the use of various ways of teaching. Students, on the other hand, can increase their achievements in the sense that they access several materials. The use of ICT in classroom practices is extremely significant for providing opportunities for students to function appropriately in an information age. This paper aims to explore the effect of the gender factor on English professors’ use of computer technologies in Moroccan higher education institutions. Descriptive analysis of means, and standard deviations were employed to analyse the collected data. Also, inferential statistics, especially the Independent-samples t- test, were used to determine the impact of gender on ICT implementation in the classrooms. The findings revealed that there were statistically significant differences in the means of males and females when using ICT in their classroom practices, t (161) = -3.921, p< 0.05.
Comparative study on quality self-assessment processes at higher education institutions in Algeria
Authors: BELIMANE Wissam , CHAHED Amina
Published: May 2022

Algeria has introduced the institutional self-assessment as Quality Assurance (QA) approach in Higher Education Institutions (HEIs) at the national level. It has been formalized in official reports communicated to the Ministry. The purpose of this study is to evaluate self-assessment practices implemented in HEIs in a comparative perspective. The method of qualitative content analysis of self-assessment reports was used, based on category system deduced from the literature review. Results show that the HEIs followed common approaches with some differences in the deployment of steps and the importance given to them. The study concludes by highlighting the implemented processes advantages and difficulties and producing important recommendations for improvement of future self-assessment exercises.
Influence of University Service Quality on Student Satisfaction and Loyalty in Bangladesh
Authors: Hasan Mahamudul , Hosen Zakir
Published: May 2022

Evaluating the service quality of higher educational institutions in Bangladesh has become crucial to ensure continuous improvement and strategy development for tertiary education sector. The present study has aimed to investigate the influence of higher education service quality dimensions on student satisfaction and student loyalty. Moreover, the study also tests the mediating impact of university reputation and external prestige between university service quality and satisfaction and loyalty.  The research work has shown the performance of selected public universities in higher education service quality dimensions. Data has been collected through a structured questionnaire from a sample of 390 graduate and undergraduate students of two public universities of Bangladesh. The study reflects that the performance on service quality dimensions of selected public universities is not satisfactory. The results of the study have shown that Teaching, Support services, Library and lab facilities and internationalization have significant influence on student satisfaction except Administrative service and Hostel facilities. Teaching, Administrative services, Library and lab facilities and Internationalization have significant influence on student Loyalty. The mediating analysis has shown that student satisfaction partially mediates between service quality and student loyalty. The results of the study have also indicated that university reputation and external prestige partially mediate between service quality and student satisfaction and loyalty. The previous studies which measure service quality of Bangladeshi higher educational institutions have applied SERVQUAL model which is not absolutely suitable for an educational institution. However, this study has applied higher education service quality model which has been uniquely developed to measure service quality of higher educational institutions.
SOSIALISASI PENGEMBANGAN DESA WISATA PLAWANGAN INDRAMAYU JAWA BARAT
Authors: Istianah Iis , Yuliah  , Runeti  , Kristian  , Kholis Nur , Hadiwibowo Imam
Published: May 2022

Pengembangan desa wisata adalah salah satu bentuk pengembangan pariwisata yang dapat di kembangkan potensi-potensi yang ada di suatu desa. Fungsi pengembangan desa wisata merupakan sebagai wadah langsung bagi masyarakat akan kesadaran adanya potensi wisata dan terciptanya pesona lingkungan wilayah tersebut. Pengembangan desa wisata dewasa ini telah menjadi alternatif pembangunan ekonomi local yang diterapkan diberbagai daerah. Salah satu desa yang dikembangkan sebagai desa wisata adalah desa Plawangan, Kabupaten Indramayu. Desa Plawangan memiliki potensi pengembangan jika dilihat dari aspek potensi fisiknya, yaitu panorama persawahan yang hijau, sumber mata air Kali Beiji, taman Sri Rahayu, home industry berupa olahan makan bawang goreng, perkebunan rempah-rempah dan sayur. Pengabdian ini bertujuan untuk mengeksplorasi potensi pengembangan Desa Plawangan Sebagai desa wisata dengan mensosialisasikannya. Pendekatan yang digunakan dalam pengabdian ini adalah metode observasi, wawancara dan dokumentasi.
SARS-CoV-2 infection in pregnancy and risk of stillbirth
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Panaitescu Anca Maria ,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania, Toma Dalila-Ana ,   Intensive Care Department, "Prof. Dr. Matei Bals" National Institute for Infectious Diseases, Bucharest, Romania, Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania, Cimpoca-Raptis Brindusa ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania, Ciobanu Anca ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania, Popescu Mihaela Roxana ,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania,   Cardiology Department, Elias Emergency University Hospital, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila“ University of Medicine and Pharmacy Bucharest, Bucharest, Romania
Published: May 2022

The COVID-19 pandemic has changed the lives of millions of people across the globe. As of November 2021, WHO has reported more than 250 million confirmed cases of SARS-CoV-2 infection with more than 5 million deaths. Despite the continuous efforts being made by the medical community to address the fundamental questions posed by the SARSCoV-2 infection in pregnant women and its impact over the mother and the offspring. The aim of this paper is to assess the evidence accumulated since the emergence of the pandemic concerning the impact of SARS-CoV-2 infection on the mother and fetus, especially addressing the risks of intrauterine death in SARS-CoV-2 positive mothers. We searched different databases up to November 2021 for variations of the sentence: "SARS-CoV-2 infection and COVID-19 and pregnancy and fetal death, stillbirth, intrauterine death". The changing physiological and immune responses during pregnancy make a pregnant woman more prone to developing severe forms of COVID-19, causing sometimes serious pregnancy complications such as fetal loss. At times mild general symptoms related to COVID-19 can cause serious fetal complications, suggesting that placental changes are responsible for fetal outcome. Infection with non-Delta variant increases the risk of fetal loss in the third trimester two times compared to healthy population, while Delta variant increases this risk four times. The exact mechanism of vertical transmission is still to be established and these aspects need further research especially assessing COVID-19 variant particularities.
Prevention of neonatal group B streptococcal disease
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Ilie Ilinca , Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Demetrian Mihaela ,   Filantropia Clinical Hospital, Bucharest, Romania, Ciobanu Anca Marina ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Cimpoca-Raptis Brindusa Ana ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Corina ,   Filantropia Clinical Hospital, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Group B streptococcal (GBS) disease and its early onset continues to pose major economic and perinatal implications regarding maternal and neonatal morbidity and mortality rates and methods of treatment. Universal GBS screening via rectovaginal culture is now recommended between 36 and 37 weeks and 6 days of gestation for all pregnant women. Timely identification of groups of women suitable for intravenous intrapartum antibiotic prophylaxis of GBS early onset infection has also proven to be effective, although less so than the universal screening approach.
The symptomatology of the gastroesophageal reflux disease and the first line therapy
Authors:   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, ", Hanghicel Teodora ,   Grigore T. Popa",   University of Medicine and Pharmacy, Iasi, Romania,   Aris Pharmacy, Iasi, Romania, Strugaru Emanuela ,   Aris Pharmacy, Iasi, Romania, Ionescu Oana Maria ,   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania, Profire Lenuta ,   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania
Published: May 2022

Over time, gastroesophageal reflux has undergone an unexpected and at the same time undesirable evolution towards the most commonly diagnosed upper gastrointestinal disease, called gastroesophageal reflux disease. The symptoms of gastroesophageal reflux disease are complex, difficult to treat and often recurrent. In order to prevent the disease recurrences, it is also necessary to establish the treatment in accordance with the gastroesophageal reflux symptoms. Unfortunately, nowadays, more and more patients of all ages go to the pharmacy with typical symptoms of gastroesophageal reflux, this ailment having a negative impact on the quality of life. This article aims to highlight the role of the pharmacist in recognizing the symptoms of gastroesophageal reflux and initiating firstline treatment.
Therapeutic management of gastrointestinal disorders
Authors:   Department of Drug Industry and Pharmaceutical Biotechnology, Faculty of Pharmacy, ", Dragan Maria ,   Grigore T. Popa",   University of Medicine and Pharmacy, Iasi, Romania, Stan Ruxandra Teodora ,   Faculty of Dental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania, Dragostin Oana Maria ,   Faculty of Medicine and Pharmacy, ”Dunarea de Jos” University, Galati, Romania, Stan Catalina Daniela ,   Department of Drug Industry and Pharmaceutical Biotechnology, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania
Published: May 2022

Chronic gastrointestinal disorders are becoming more widespread among the population, therefore physicians and pharmacists are meant to use their knowledge and deliver appropriate treatments according to the needs of each patient, relying on new research results and medical practice acquisitions. Common chronic gastrointestinal disorders are: gastroesophageal reflux disease, dyspepsia, irritable bowel syndrome, coeliac disease, inflammatory bowel disease, with a growing global incidence and prevalence, especially in Western countries, being closely linked to socio-economic progress. The effect of patient counseling is seen in improving the patient`s quality of life. As part of medication therapy management, patient counseling focusing on compliance, diet and medications is an effective tool to improve health-related. Such services improve outcomes in chronic gastrointestinal disorders.
Pharmacist-doctor collaboration during the pandemic, effective management of gastrointestinal pathology
Authors:   Clinical Pharmacy, “Sf. Spiridon” County Emergency Hospital, Iasi, Romania, Mandici Alexandru , Munteanu Ana ,   Clinical Pharmacy, “Sf. Spiridon” County Emergency Hospital, Iasi, Romania, Cojocariu Daniel ,   Clinical Pharmacy, “Sf. Spiridon” County Emergency Hospital, Iasi, Romania, Iacob Andreea-Teodora ,   Pharmaceutical Chemistry Department, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania
Published: May 2022

The novel coronavirus SARS-CoV-2 is responsible for the emergence of a potentially life-threatening disease (COVID-19) which has put tremendous pressure on the healthcare systems worldwide. Pharmacists, either from hospital or community pharmacies, are playing an essential role in the management of current COVID-19 pandemic as trustworthy partners of physicians, contributing to the reduction of drug-induced adverse events through medication guidance, thereby improving patient compliance and helping them regaining their confidence to overcome the disease. In the management of gastrointestinal symptoms that may or may not be in the context of COVID-19, pharmacists should recommend that patients consult a physician when gastrointestinal pathology is complex and associated with other symptoms.
Ethics in patient counseling and pharmaceutical practice by emotions management
Authors:   Department of Analytical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Sava Alexandru , Sava Elisabeta ,   Specialist Pharmacist, The College of Pharmacists from Romania, Panainte Alina ,   Department of Analytical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Focsa Alin ,   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Bibire Nela ,   Department of Analytical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania
Published: May 2022

Effective communication is an essential part of pharmacy practice aimed to ensured counsel patients about their prescribed medicines. This will lead to a rational use of medicine with an improved therapeutic outcome, increasing compliance and decreasing confusion and insecurity. For the purpose of legal regulation of pharmacist-patient communication, professional associations from different countries have developed the codes of ethics for pharmacists. As in other countries, the Code of Ethics of Pharmacists in Romania and Law 81/1997 guarantee respect for the rights and dignity of the patient. Communication is a highly complex area and ability to understand a patient’s feelings could be the key to ensuring high-quality interactions. Developing that relationship can mean addressing patients’ emotional responses to therapy, as well as acknowledging their concerns or frustrations. Through careful analysis of the communication in pharmaceutical practice we can help develop skills, tools and processes to make patient encounters as optimal as possible. This paper analyses some tools to understand a patient’s feelings that could be the key to ensuring high-quality interactions.
Skin cancer and pregnancy
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Scutelnicu Ana , Ciobanu Anca Marina ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Corina ,   Filantropia Clinical Hospital, Bucharest, Romania, Demetrian Mihaela ,   Filantropia Clinical Hospital, Bucharest, Romania, Cimpoca-Raptis Brindusa Ana ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Skin cancer during pregnancy is common, with malignant melanoma being the most frequent and the most aggressive. Any pigmented skin lesion that suffers changes should be examined by a specialist and if considered high-risk, biopsy should be performed right away and not postponed as it is thought to be safe during pregnancy. Recent studies showed that it has the same outcome compared with the non-pregnant state, if diagnosed and treated as soon as possible. Diagnosis of skin cancer, including melanoma, does not necessarily require an early delivery or termination of pregnancy, if in the first trimester, except for pregnant patients with poor prognosis (advanced disease) that need more aggressive, systemic treatment. Management needs to be established in specialized centers with a multidisciplinary team. Monitoring should be performed by a team consisting of an obstetrician, a maternal-fetal medicine specialist, a neonatologist, and an oncologist.
Peptic ulcer disease during pregnancy
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Dumitru Andreea Elena , Gica Corina ,   Filantropia Clinical Hospital, Bucharest, Romania, Demetrian Mihaela ,   Filantropia Clinical Hospital, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ciobanu Anca Marina ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Peptic ulcer disease during pregnancy has to be separated from its management and treatment in the general populations. It was demonstrated to have a low incidence rate, with symptoms, frequency and complications decreasing due to maternal hormones. We aimed to outline the actual management and treatment of peptic ulcer disease (PUD) during pregnancy. We performed a literature review by searching relevant information on the subject in PubMed database using the keywords: peptic ulcer disease, pregnancy, H2 receptor antagonists, proton-pump inhibitors, fetal, congenital abnormalities. Current literature studies show a decreased rate of both incidence and symptoms in pregnant women compared to the general population. Step by step therapy combines both lifestyle modifications and medical drugs for the benefit of both mother and fetus. It is difficult to differentiate from the beginning between PUD and gastroesophageal reflux (GERD) or hyperemesis gravidarum, due to similar symptoms. An accurate anamnesis and a good understanding of serological and paraclinical investigations can define the right diagnosis. Management of this pathology in a pregnancy state can be difficult, but a compliant attitude of the mother together with an organized medical approach can facilitate treatment.
Trauma in pregnancy
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Atanasescu Ioana Emanuela , Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ciobanu Anca ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Trauma is complicating 1 in 12 pregnancy and is considered to be the first cause of non-obstetrical maternal death. Frequently encountered complications are preterm delivery, placental abruption or spontaneous abortion. Presence of the gravid uterus is a major contributor that increases the risk of the occurrence of possible wounds, and as the pregnancy progresses, multiple changes that occur can make the management of the pregnant patient harder. Studies have shown that domestic abuse should not be overlooked. First evaluation needed for pregnant trauma woman comprise complete blood count, coagulation profile, Rh factor determination, urine analysis, electrolytes and glucose, toxicology screening and the Kleinhauer-Betke (KB) test. Also, diagnostic imaging is not discouraged, and may raise and also confirm the suspicion for placental abruption or uterine rupture. In case of cardiac arrest and unsuccessful resuscitation of the mother within 4 minutes, literature recommends a perimortem cesarean delivery, if gestational age is above 23 weeks and the fetus is potentially viable.
Acute appendicitis in pregnancy
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Zechiu Ioana , Ciobanu Anca Marina ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Corina ,   Filantropia Clinical Hospital, Bucharest, Romania, Demetrian Mihaela ,   Filantropia Clinical Hospital, Bucharest, Romania, Cimpoca-Raptis Brindusa Ana ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Acute appendicitis is the most frequent non-obstetrical surgical emergency encountered in pregnancy with negative maternal and fetal outcomes, mostly attributed to appendicular perforation. The purpose of this article is to discuss the characteristics in diagnosing appendicitis in pregnancy, recommendations of management, as well as maternal and fetal outcomes. It is significantly challenging to diagnose appendicitis in pregnancy due to the anatomic displacement of the appendix caused by the enlargement of the uterus (which may cause uncommon symptomatology), the physiologic leukocytosis of pregnancy, the raised prevalence of abdominal discomfort along with the inability to perform computed tomography because of the radiation exposure of the fetus. These particularities may delay an accurate and timely diagnosis which is of utmost importance in order to avoid the significant complications associated with peritonitis. Rapid surgical intervention (especially laparoscopy) is recommended, nevertheless, the key in managing appendicitis in pregnant patients is finding a balance between the risk of delaying the diagnosis and consequent perforation against the risk associated with a negative appendectomy.
Acute cholecystitis in pregnancy
Authors:   Filantropia Clinical Hospital, Bucharest, Romania, Atanasiu Ioana Emanuela , Gheoca George Dumitru ,   Filantropia Clinical Hospital, Bucharest, Romania, Botezatu Radu ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ciobanu Anca Marina ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Corina ,   Filantropia Clinical Hospital, Bucharest, Romania, Cimpoca-Raptis Brindusa Ana ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Demetrian Mihaela ,   Filantropia Clinical Hospital, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gica Nicolae ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Panaitescu Anca Maria ,   Filantropia Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2022

Acute cholecystitis is the most common non-obstetric abdominal emergency in pregnant patients. It is a consequence of increased formation of cholelithiasis, and occurs due to inflammation of the gallbladder, usually caused by the blockage of the cystic duct. There is also described the appearance of cholecystitis without the presence of gallstones, and this is named as acalculous cholecystitis. Elevated levels of estrogen and progesterone are thought to be a cause of women’s increased predisposition to this condition. In pregnancy, literature describe the appearance of gallstones in 1% to almost 3% pregnancies, and it is known that pregnancy by itself affects the contractility of gallbladder. For sludge and gallstones, even if there is a large range of symptoms, almost up to 50% of patients are asymptomatic. Acute cholecystitis is suspected in a patient with continuous pain in the right upper quadrant, alongside anorexia, vomiting, and fever. Laboratory findings in acute cholecystitis show leukocytosis, an elevated level of bilirubin, up to 4 mg/dl and elevated liver tests. The most useful imaging tool in diagnosing gallstones and further acute cholecystitis is an abdominal ultrasound. Any pregnant women with upper right quadrant pain should be hospitalized to exclude other differential diagnoses and for pain management, usually done with acetaminophen. Supportive care treatment includes administration of intravenous fluids and when necessary antibiotic therapy. Recent studies have showed that interventional surgery by itself brings some associated risks during pregnancy, but with an experienced team of surgeon, anesthesia specialist, and obstetrician, outcomes are better, no matter the trimester of pregnancy.
Model to improve charting performance for physicians
Authors: Mammoliti Maryna , Ly Adam , Chen Cindy
Published: May 2022

Timely, accessible, and comprehensive charting of medical care is a complex issue that has clinical, legal, regulatory, and financial implications. Documentation, along with the rise in other administrative tasks, is a factor contributing to physician burnout. We posit that difficulties with charting are multifactorial and can stem from physician, patient, and environmental factors. Physician leaders have a responsibility to enforce charting standards and deadlines and are best positioned to lead charting-related solutions. To assist physician leaders, we propose a charting performance model as a tool to assess charting difficulties within their organizations.
Analysis of Impaired Functions and Disability Due to Diseases of the Blood and Hematopoietic Organs with Regard to the Need for Rehabilitative Measures
Authors: Fedorova Irina V. , Zapariy Natalya S. , Samusenko Anastasia G. , Bolotov Denis D. , Koneva Elizaveta S.
Published: May 2022

Diseases of the blood and hematopoietic organs are one of the urgent medical and social problems. The effectiveness of the rehabilitation measures carried out depends on their compliance with functional disorders and the degree of disability associated with them.
Aim. To study the dysfunction of the disabled person’s body and, based on them, to assess the limitation of vital activity and the degree of their severity.
Material and methods. The study was generated in xlsx format and uploaded to the environment for statistical data analysis (https:www.r.project.org) using methods: documentary, data copying (184 units). Data processing and analysis were performed using scripts. For continuous normally distributed variables, the average value, the standard deviation, were calculated when comparing two groups of studies — the t–criterion, when comparing several groups — the ANOVA. Medians, 1st and 3rd quartiles were calculated for continuous abnormally distributed variables, and when comparing groups, the Kruskall-Wallis criterion was used. Absolute and relative frequencies were calculated for categorical variables, and when checking the conjugacy tables of 2x2 sizes, the Chi-square criterion or the Fisher criterion was used. Spearman’s rank correlation index was calculated for each pair of categorical variables. The significance level when testing statistical hypotheses was assumed to be 0.05.
Results. It was found that in patients with blood and hematopoietic organs diseases, the greatest proportion in the structure of impaired functions were violations of the functions of the blood system and immunity, cardiovascular system, neuromuscular, skeletal and movement-related (statodynamic) and total functions, the severity of which, as a rule, was moderate. In the structure of restrictions of vital activity, the following restrictions of vital activity were determined: self-service abilities of the 1st degree, self-locomotion of the 1st degree and work activity of the 1st degree.
Conclusion. Expert-rehabilitation diagnostics based on samples of different numbers and nosology among persons who have passed examination at the ITU bureau, allows us to form an idea of the amount of rehabilitation measures required for them, including in the conditions of assessment according to the requirements of the International Classification of Disorders, Disability and Social Insufficiency.The expert-statistical assessment of this contingent of disabled people allows us to predict the volume of examinations, to assume a prognosis for the course of diseases and to plan the volume of medical and rehabilitation care.
The Effectiveness of Rehabilitation in a Day Hospital for Patients Previously Suffered from Covid Pneumonia
Authors: Guryanova Evgenya A. , Kuzminykh Anna F. , Peredreeva Alexandra K.
Published: May 2022

Aim. To research the eff ectiveness of the third stage of rehabilitation in patients who have had pneumonia caused by the Covid-19 virus.
Material and methods. A retrospective study of medical records was carried out on the basis of a medical rehabilitation department of the Sanatorium “Chuvashiyakurort” day hospital (Cheboksary, Chuvash Republic). The research included 124 people admitted to stage 3 of rehabilitation after suffering pneumonia associated with a new coronavirus infection in the period from April 2021 to September 2021. The rehabilitation included physical exercise therapy, dry carbon dioxide baths, low-frequency magnetotherapy, mud applications, halotherapy and massage procedures as well as psychotherapy methods.
Results and discussion. As a result of rehabilitation, an improvement was achieved among all groups of patients: the median of the rehabilitation routing scale decreased from moderate (3 points) to mild (2 points). According to the results of the six-minute walk test after rehabilitation, an increase in distance from 100.00 m to 220.00 m was recorded among all groups of patients, the maximum increase in distance for both men and women was observed in the age group of 50-59 years, the minimum — in men and women of 60–69 years. In the group of patients with the comorbid diseases, the six-minute walk test scores were lower than in other group. In all age groups, the tolerance of physical activity on the Borg scale decreased from 2 to 1 in both women and men, except for women in the age group of 60–69 years, and men of 60–79 years (from 3 to 2). According to the BDI and TDI scales, an increase in the degree of necessary efforts was recorded: the indicators before rehabilitation were 3, after — 4 among all groups of patients. The severity of dyspnea on the mMRC scale had a positive trend: the median before rehabilitation was 1, after — 0 among men and women of all ages. The combination of physiotherapy exercises and physiotherapy procedures is the most effective in the process of rehabilitation. It is necessary to motivate patients to continue rehabilitation activities at home or in the sanatorium and resort environment because of persistent symptoms of breath shortness, sleep disorders, incomplete restoration of exercise tolerance.
Conclusion. Comprehensive rehabilitation of patients after pneumonia associated with the new coronavirus infection caused by SARS-CoV-2 improves the general condition, increases exercise tolerance and helps to restore activity in everyday life, and improves the quality of life.
Eurasian guidelines for the diagnosis and treatment of pulmonary hypertension associated with congenital heart defects in adults (2021)
Authors: Chazova I. E. , Gorbachevskij S. V. , Martynyuk T. V. , Shmal’c A. A. , Valieva Z. S. , Baryshnikova I. Yu. , Glushko L. A. , Gramovich V. V. , Azizov V. A. , Veselova T. N. , Danilov N. M. , Zelveyan P. A. , Ivanov S. N. , Lazareva I. V. , Matchin Yu. G. , Mukarov M. A. , Nakonechnikov S. N. , Sarybaev A. Sh. , Stukalova O. V. , Shalaev S. V.
Published: May 2022

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INVESTMENT CHARACTERISTICS OF INDONESIAN GOVERNMENT BOND MARKET DURING THE COVID-19 PANDEMIC
Authors: Ganchev Alexander
Published: May 2022

The purpose of the study is to define the main investment characteristics of the Indonesian government bond market during the COVID-19 pandemic. The subject of the analysis is the yield to maturity yield curve of Indonesian government bonds, the dynamics for the period 2 January 2020–15 February 2022 is analyzed with various quanti-tative methods such as descriptive statistical analysis, time series analysis, correlation and autocorrelation analysis, probability distribution analysis, principal component analysis and graphical analysis. The study reveals that under the COVID-19 pandemic, the yield curve on Indonesian government bonds is highly stable and lacks the strong general volatility of highly developed debt markets during the same period. Quantitative analysis shows that the yield of the in-vestigated bonds has many of the well-studied characteristics that are present in the developed debt markets. However, there are some specifics and anomalies, such as a strong correlation along the entire yield curve and inhomogeneous volatility of medium-term yields. Therefore, despite the probable existence of incorrectly priced debt instruments, In-donesian government bonds should be considered by investors as an appropriate instrument for hedging interest rate risk in the COVID-19 environment.
ASSESSMENT OF THE EFFECT OF REGULATOR’S COMMUNICATION ON THE FINANCIAL MARKET PARTICIPANTS
Authors: Freimanis Kristaps , Šenfelde Maija
Published: May 2022

There is significant discussion in the academia and industry regarding over-regulation and under-regulation of the financial markets. Some discussion has been devoted to the transparency requirements for market players im-posed by the regulator and their impact on the financial market. However, in the view of the authors, there is a lack of discussion on the effects of regulator communication on financial market participants. Thus, the aim of this paper is to contribute to this discussion. Authors review methods used in assessing central banks’ communication effects on the financial markets and based on them develop the approach for regulator’s (in this case central bank) communication effect assessment on the financial market participants. The model is validated on the euro area central bank and two major economies. The results show that a lot of adverse market participants’ reactions on the signals from the central bank’s speeches have been observed.