bluuebunny/crossref_metadata_2025 huggingface dataset:
Streptozotocin and diabetes: Modulatory role of an aqueous extract of cactus on kidney histo-architecture of model
Authors: Uthman Ademola Yusuf  , Hellen Kabwe  , Francine Kafula  , kalande Kaimba  , Wandi Kalipenta  , John Mulemena  , Sam Beza Phiri  , Michelo Miyoba  , Adrian Phiri  , Bwalya Bupe Bwalya  , Isabel Namfukwe Luambia  , Precious Simushi  , Aminat Adejoke Yusuf
Published: August 2022

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The prevalence of DM globally in 2019 was estimated to be 9.3% of the world’s population. Complications of DM include nephropathy, neuropathy, retinopathy, stroke and coronary heart disease. Traditional plants have been used in the management of diabetes mellitus, an example is the cactus plant. This study aimed to shade more light on the effect of an aqueous extract of cactus on the kidney histo-architecture of the diabetic Wistar rats. Thirty adult male Wistar rats weighing between 160-200g and were randomly grouped into five consisting of six rats each: group A. normal control, group B. diabetic only, group C. diabetic treated with Cactus and group D. diabetes treated with Metformin only and group E Cactus extract only. Diabetes was induced by a single intraperitoneal injection of Streptozotocin of 70mg/kg/body weight. After 72 hours of uninterrupted diabetes (blood glucose≥ 7mmol). The cactus extract and Metformin was administered orally at 100 mg/kg body weight daily for four weeks and blood glucose level were recorded weekly. After the fourth week of administration, animals were sacrificed by euthanasia. The kidneys from all the groups were weighed and their weight recorded and were fixed in 10% formal saline. Data was analyzed using one way ANOVA p<0.05 was considered significant and the graphs were plot using excel. The findings of this study showed that the blood glucose level of Diabetic +Cactus group and diabetes + Metformin were significant when compared to the diabetic group (p<0.05). The body weight and relative organ weight of Diabetic +Cactus group and diabetes+ Metformin when compared to the diabetic group was significant P<0.05. Histologically, the diabetic group that showed disruption of macula densa and a large urine space compared to the Wistar rats in the Diabetes+cactus group and Diabetes+metformin group that showed little disruption in macula densa were observed. From the results obtained, the aqueous cactus extract has the ability to lower blood glucose level in diabetic Wistar rat and is histologically renoprotect to the damage caused by Diabetes mellitus.
Evaluation of solid biomedical waste management practices in six health facilities in southern Benin
Authors: Denise Assiba DAVOU  , Hervé Agbomakou GBEGNIDE  , Martin Pépin AÏNA  , Edgard-Marius OUENDO
Published: August 2022

Introduction: Health care generates biomedical waste that present risks to humans and the environment if poorly managed. The objective of this study was to assess the management practices of solid biomedical waste in southern Benin. Methods: This was a descriptive cross-sectional study conducted in six health facilities. The study included 12 administrative agents selected by reasoned choice and 431 health care agents selected by convenience. The data were collected by questionnaire, interview, and observation. They concerned variables related to the production, the practice of managing, knowledge of the impact of solid biomedical waste on the environment and health, training and protection of personnel. Data analysis was done with R 4.5.0 software. Quantitative variables were described by median and interquartile range. Proportions were compared with the chi-square test or that of Fisher at the threshold of 0.05. Results: The health facilities did not have solid biomedical waste management database. Sorting was not systematic in 59.5 %. Final storage locations did not meet standards. Almost one in four health workers (24.4 %) were injured by biomedical waste. Overall, 45.8 % of the staff had been trained at least once on biomedical waste management. 61 % of the staff surveyed were vaccinated, hepatitis B (41.3 %), tetanus (32.9 %). Conclusion: In view of the results, it is necessary to ensure the on ongoing awareness and training of medical staff in the sorting and packaging of biomedical waste and to set up an efficient and sustainable solid biomedical waste management system with effective monitoring mechanisms.
Pengobatan Medis oleh Perawat dan Bidan dalam Manajemen Terpadu Balita Sakit
Authors: Aloysius Tri Joehanto
Published: August 2022

This study analyzed a normative legal research on conflict resolution of norms of legislation related to the implementation of Integraded Management of Childhood Illness abbreviated as IMCI or Manajemen Terpadu Balita Sakit abbreviated as MTBS which discusses two problem fornulations, namely: first, are nurses and midwives have authority to conduct medical treatment in the application of MTBS? Second, what are the juridical consequences of medical treatment by nurses or midwives in the application of MTBS? This research uses a statue approach and conceptual approach. Nurses and midwives do not have the authority to provide medical treatment in the application of MTBS on the basis of Permenkes Nomor 25 Tahun 2014 tentang Upaya Kesehatan Anak Pasal 25 ayat (2) dan ayat (3) that MTBS is performed by trained nurses and midwives and in its implementation should be supervised by the doctors who have been trained, as this may lead to conflict of norms of existing legislation because of the authority to make clinical decisions based on the diagnosis of a disease and medical treatment efforts in the application of MTBS is the authority of the medical or doctor as regulated in Undang-Undang Nomor 29 Tahun 2004 tentang Praktik Kedokteran Pasal 35 ayat (1). Health workers in carrying out practices should be conducted in accordance with the authority based on their competence to ensure legal certainty and sense of justice in order to improve the welfare of the community. On the one hand providing protection for doctors, nurses and midwives and on the other hand provides protection also for users of health services to achieve a quality service, safe, non-discriminatory and remain affordable.
Perlindungan Hukum bagi Bidan Praktik Mandiri dalam Menjalankan Praktik Kebidanan
Authors: Rezky Fransilya Sumbung
Published: August 2022

Legal Protection for Practicing Midwives is regulated in Law Number 36 Year 2014 concerning to Health Workers, Articles 57 and 75. Article 57 stipulates that: "personnel in carrying out practices have the right to legal protection as long as they carry out their duties in accordance with professional standards, professional service standards, and standard operating procedures." Article 75 stipulates that: "in carrying out the practice, health workers have the right to legal protection in accordance with statutory provisions". Likewise in Permenkes 1464 / Menkes / Per / X of 2010 concerning Permits and Practices of Midwives Article 19 stipulates that: "in carrying out practice / work, midwives have the right to obtain legal protection in carrying out practice / work as long as it is in accordance with standards". This paper will explain about the authority of midwives in implementing midwife practices and legal protection for midwives in implementing independent midwives. The purpose of this paper is to analyze the authority of independent practice midwife services and to examine the form of legal protection for independent practicing midwives in the implementation of independent practice midwives. The author uses a research method with a normative juridical type and the approach issue using statutory approach, a conceptual approach and a comparative approach.
Pertanggungjawaban Hukum Direktur Rumah Sakit Dalam Pelaksanaan Terapi Oksigen Hiperbarik
Authors: Siti Hamidah
Published: August 2022

The community's need for quality and affordable health services cannot be delayed any longer and a dynamic and increasingly critical Indonesian society demands sophisticated and humane professional services. The Ministry of Health has a health service policy that is based on the vision of an independent community to live healthily and has a mission to make people healthy. One of the health services that is needed by the community is hyperbaric oxygen therapy, which is a therapy using pure oxygen in a high-pressure room which was originally used as the main treatment for diving diseases, now hyperbaric has also been used as an additional treatment and other treatment options for the general public to help cure various diseases. With the increasing public demand for hyperbaric oxygen therapy services and many hospitals that provide services for this therapy. The government through the Minister of Health needs to issue a Decree of the Minister of Health Number 120 / MENKES / SK / II / 2008 concerning Hyperbaric Medical Service Standards. The establishment of operational standards in the implementation of hyperbaric oxygen therapy is a reference for the responsibility of the Hospital Director as the executor of the therapy service provider.
Kompetensi Tambahan Dokter Gigi Dalam Peraturan Perundang-Undangan di Indonesia
Authors: DASUKI
Published: August 2022

Lahirnya UU Praktik Kedokteran telah mengubah paradigma penyelenggaraan pelayanan kesehatan, praktik kedokteran gigi dari regulasi berbasis administrasi menjadi kompetensi yang menjadi domain Konsil Kedokteran Indonesia (KKI) dan Organisasi Profesi, kewajiban mengikuti perkembangan ilmu kedokteran gigi. dan teknologi dalam Pengembangan Program Berkelanjutan sebagai proses pembelajaran sepanjang hayat, untuk sertifikasi ulang kompetensi dan tambahan kompetensi dan Surat Tanda Registrasi (STR) kompetensi sebagai bentuk pengakuan dan kewenangan yang diberikan setelah mengikuti PKB sesuai dengan prinsip dan norma hukum yang berlaku agar tidak menimbulkan permasalahan dalam pelaksanaannya dan dapat membuka seluas-luasnya program kompetensi tambahan dalam rangka peningkatan kompetensi profesional, sebagai solusi atas keterbatasan pelayanan spesialis di Indonesia. Penelitian ini bertujuan untuk mengkaji sifat dari kompetensi tambahan dokter gigi dan institusi yang memiliki kewenangan untuk menyediakannya dalam peraturan perundang-undangan yang berlaku di Indonesia. Penelitian ini merupakan penelitian yuridis normatif dengan pendekatan undang-undang, pendekatan konseptual dan pendekatan komparatif. Hakikat Kompetensi Tambahan Dokter Gigi adalah kompetensi yang diperoleh melalui PPK sebagai pembelajaran sepanjang hayat yang diselenggarakan oleh Organisasi Profesi dan lembaga yang berwenang untuk mengesahkan Kompetensi Tambahan Dokter Gigi di Indonesia, yaitu Konsil Kedokteran Indonesia dengan menerbitkan Tanda Daftar Kompetensi Tambahan sesuai dengan Undang-Undang Nomor 29 Tahun 2004 Tentang Praktik Kedokteran, Peraturan Konsil Kedokteran Indonesia tentang Kewenangan Tambahan Dokter dan Dokter Gigi, Peraturan Konsil Kedokteran Indonesia tentang Pendaftaran Dokter dan Dokter Gigi, Peraturan Konsil Kedokteran Indonesia tentang Kualifikasi Tambahan Dokter Spesialis dan Dokter Gigi.dentist, additional competence, legislation
Analisis kelayakan usaha tani Kopi Arabika di Kabupaten Simalungun
Authors: Siadari Ulidesi , Batubara Heri Dia Anata , Pane Pertama Yul Asmara , Shanty Ade Maya Mei
Published: August 2022

This study aims to determine the feasibility of farming and analyze the sensitivity of Arabica coffee farming to the increase in costs and the decrease in the selling price of Arabica coffee in Simalungun Regency. The population of this study were Arabica coffee farmers, the number of respondents in this study was 60 people. The method used in the feasibility analysis is to calculate the R/C ratio, Return on Investment (ROI), NPV, IRR, Net B/C, and PP. Meanwhile, analyzing the sensitivity of farming is carried out using the method of increasing costs and decreasing the selling price of Arabica coffee in Simalungun Regency. Based on the feasibility analysis of the farming business carried out, Arabica coffee farming is categorized as still feasible to cultivate. Meanwhile, Arabica coffee farming is more sensitive to the decline in the selling price of Arabica coffee by 10% and 20%, respectively. The feasibility analysis and sensitivity analysis are one of the things that encourage people to continue cultivating Arabica coffee because based on the feasibility analysis and sensitivity analysis, Arabica coffee is suitable for cultivation.
Evaluation of potato hybrids by the dynamics of accumulation of yield and starch content in tubers in agro-ecological conditions of the Volga-Vyatka region
Authors: Sintsova N. F. , Lyskova I. V. , Kratyuk E. I. , Arkhipov V. M.
Published: August 2022

The article provides the results of studying the accessions of potato in the nursery of dynamic test for 2019-2021 in agro-ecological conditions of the Volga-Vyatka region (Kirov region) by the yield and starch content in tubers. The objects of the study were 10 hybrids bred by Falenki Breeding Station - branch of Federal Agricultural Research Center of the NorthEast named N. V. Rudnitsky (FARC North-East). Early variety Udacha (Russian Potato Research Centre), middle-early variety Nevsky (North-West Research Institute of Agriculture), mid-season variety Chaika (FARC North-East) were taken as standard. Promising potato hybrids of different maturity groups with high potential yield have been selected: early variety 172- 13 (24.1 t/ha), middle-early varieties 27-07 (22.7 t/ha), 179-10 (22.9 t/ha), 233-12 (24.0 t/ha), mid-season 232-12 (22.4 t/ha). By favorable agro-weather conditions (2019) the highest yield (more than 28.0 % t/ha) was developed by hybrids: early 172-13, middle-early 27-07 and 179-10, mid-season 580-13. In the unstable environment of 2020 and 2021 the following hybrids were noted: middle-early 233-12 (19.6 and 27.7 t/ha) and mid-season 232-12 (19.2 and 24.0 t/ha). In the group of middle-early varieties with high starch content (15 % and more) during the years of study there were selected the hybrids 27-07, 179-10, 72-13, 182-13. The maximum accumulation of starch (18-21 %) was noted in mid-season hybrid 580-13. Significantly high inter-seasonal correlations by yield on the 60th day from the planting have been established, that characterized all the varieties as the most stable. On the 80th day there were noted weak inter-seasonal correlations that proved the instability of this parameter during the years which differed in weather conditions (strong interaction “genotype-environment”, that is the yield of variety samples during this period depended on the effect of environment factors). High inter-seasonal correlations by the parameter “starch content” on the 80th day have been revealed. The varieties and hybrids by the time of complete ripeness preserved the stability by this indicator unlike early harvesting periods when they were more dependable on the fluctuations of environmental factors.
The assessment of promising fiber flax lines of breeding variety testing according to the main agronomic traits and adaptability
Authors: Stepin A. D. , Rysev M. N. , Ryseva T. A. , Utkina S. V.
Published: August 2022

The purpose of the research is a comprehensive assessment of promising lines of fiber flax according to the main agronomic traits and adaptability based on the results of breeding variety testing in the conditions of the North-Western region of the Russian Federation. The research was carried out in the conditions of Pskov region in 2016-2019 on sod-weakly podzolic light loamy well-cultivated soil. The hydrothermal coefficient (HTC) for the growing season was in 2016 – 1.98, in 2017 – 1.60, in 2018 – 0.95 and in 2019 – 1.44. Abiotic conditions of the year had the greatest significant impact at 5 % significance level on the formation of plant height (79.2 %), the yield of flax seeds (83.6 %), flax straw (78,0 %) and flax fiber (68.5 %), the duration of the growing season (58.3 %). The share of the genotype prevailed in the formation of the fiber content in the stem (75.0 %). Variability was greatest in the yield of flax seeds (CV = 26.4...34.1 %); mainly average ‒ in the yield of flax straw and flax fiber (CV = 11.3…21.5 %) and weak ‒ in other characteristics (CV = 1.5...10.5 %). Based on the results of the research according to the complex of agronomic traits, three best lines of practical interest have been identified: P-4382-3-2 f-3, P-4453 c-6 and P-4629 sh-1. All of them belong to early ripening (the growing season is 77...79 days), are resistant to lodging (4.1...4.7 points) and fusarium wilting (86.5...93.3 %), tall (78...81 cm), have the yield of flax straw (50.2...51 c/ha) and flax seeds (5.9...6.9 c/ha) at the level of standard variety Voskhod. They are characterized by high fiber content (35.9...39.6 %) and flax fiber yield (18.4...19.9 c/ha), exceeded the standard by 2.5...5.9 % (abs.) and 7.6...17 %, respectively. Based on a comprehensive assessment of the breeding material according to productivity and adaptability parameters, using the ranking principle, the same genotypes are the most adapted to the soil and climatic conditions of the NorthWestern region, as having scored the lowest amounts of ranks. Their use in breeding programs will contribute to the development of new varieties that ensure high and stable yields of flax products of good quality.
Phytochemical characteristic and activity of medicinal raw material from the leaves of pharmacopoeial plant
Authors: Timofeev N. P.
Published: August 2022

In 2016-2020 there was carried out a comprehensive study of the problem on involvement into the industrial turnover of ecdysterone-containing substance from the leaf parts of Rhaponticum carthamoides, which is included in the list of plants of the State Pharmacopoeia, in relation to the activity and safety of harvested raw materials. Studied were phytochemical and qualitative characteristics of medicinal raw materials obtained by alternative technology (vegetative shoots instead of roots with rhizomes). Cultivated by organic cultivation in the European North-East of Russia (Archangelsk region) with a cool and humid climate, in an agropopulation with a density of 24-28 thousand plants per 1 ha. Harvesting was carried out at the beginning of the budding phase, the concentration of the active ecdysterone substance was determined by the pharmacopoeial method of high performance liquid chromatography (HPLC) analysis. It has been established that the objects of collection are the fractions of young and adult rosette leaves, where the accumulation of large amounts of ecdysterone is associated with the presence of increased amounts of protein substances (r2 = 0.99-0.98) and there is an inverse negative dependence on fiber (r2 = -0.99…-0.94). An indicator of increased synthesis of ecdysterone is the level of crude protein of 33-27 %, at which the concentration of ecdysterone reaches 4850-3550 mg/kg (0.49-0.36 %) at a standard of 1000 mg/kg (0.1 % based on dry substance). A high degree of availability of ecdysterone from the substance in aqueous extracts, in the temperature range from -10 to +100 ºC, with subsequent preservation of the active substances during the day by 93-98 % was revealed. Total yield of extractive substances is 50.2 % (with the standard value of 12.0 %). Complex biological activity of the extract in biotests was characterized by a stimulating effect at high dilution (10-9-10-11 M per ecdysterone) and inhibitory at low dilution (1:100). Medicinal raw materials meet the established sanitary and toxicological safety standards for the content of pollutants: it does not accumulate heavy metals (Hg, Cd, As, Zn; Ni, Cu, Cr) above the background level; there are no prohibited chlorine and organophosphorus compounds; radionuclide, nitrate and nitrite content is below norms of maximum allowable concentration.
Aspects of aerobic endurance in middle school students
Authors:   . Secondary School ”Zelk Zoltan” Valea lui Mihai, 6th Ady Endre street, 415700, Valea lui Mihai, Romania, KÖRMENDI Gyulla , LUCACIU Simona ,   Secondary School ”Dimitrie Cantemir” Oradea, 2A Sextil Pușcariu street, 410512, Oradea, Romania, LUCACIU Gheorghe ,   University of Oradea, Department of Physical Education, Sport and Physical Therapy, 1st University street, 410087, Oradea, Romania
Published: August 2022

The general, harmonious physical development of school youth is a major desideratum included among the aims of physical education promoted by all authors with concerns in this field, being the most important requirement of the ideal of physical education, a presence in any stage of design, planning, organization and development. this activity. In accordance with this task of great importance for school physical education, we mention that this paper aims primarily at the student, but also to improve the activities of teachers in the direction of achieving higher levels, a very important goal in general physical training of students and mainly the development / optimization of aerobic endurance. Goal: the role of this paper is to highlight the effects that “application paths” can generate as means oriented towards the development of aerobic endurance. Methods: In carrying out the research we mainly used the field test method, the observation method and the statistical-mathematical method. Results: The means used in the form of "application path" influence and demand at the same time the cardiovascular and respiratory systems and automatically lead to the increase of somato-functional indices of students.
How Acquired Technical Skills Surpass Cognitive Personality Traits of PR Employees: A Case Study of Economy Hotels in Egypt
Authors: Hany B. Moussa, Mohamed , Abdul-AAL Fatma , Mohamed Khair Hassan
Published: August 2022

The hotel industry is one of the world’s oldest commercial industries (Bovin 2019). The industry is rapidly expanding, necessitating the assignment of tasks to skilled staff that will ensure client satisfaction. Hotel investment activities in African countries have lately increased (Ernst & Young 2013), and new hotel developments have become the fastest rising economic activity not just in Sub-Saharan Africa but also globally (Ernst & Young 2013). Human resource allocation in hotels refers to the assignment of hotel workers to service tasks, where staff can only be engaged for a certain amount of time due to labor laws. Human resource allocation requirements differ depending on the application area (Kayoko et al. 2011). The system’s success is frequently ascribed to how well it manages human resources. It is a critical issue in order to improve performance. When a task requires certain abilities, such as accounting skills, a human resource that handles the activity should have those skills in order to complete the assignment efficiently (Ernst et al. 2014). On the other hand, the impact of personality traits on employee job performance is undeniable, and many businesses take use of this effect. One of the most important psychological aspects influencing human behavior is personality. It is said to be crucial in the workplace. Personality qualities have an essential influence in improving an employee's job performance’s efficiency and are probably much weighted than technical ones. Personality traits are favorably connected with job success, and conscientiousness has attributes that directly correspond to job performance of employees with the highest weights, according to previous researches. It is the main objective of this paper to find out whether personalities traits from one side outweighs employees’ skills from the other side taking PR employees of economy hotels in Cairo as a sample for application and how could this contribute to the performance of the hotel. Keywords: attitudes, skills, cognitive personality traits, PR department, economy hotels, reputation and performance
Imagined Women: Bearing, Rearing, and Wearing the Tajik Nation
Authors: Nozimova Shahnoza
Published: August 2022

In contemporary Tajikistan, the onus of national identity’s (re-)production has been disproportionately placed on women. Decisions about female bodies, dress, duties, and the limits of women’s roles in the public and private spaces serve as important differentiating markers and mobilization tools for the competing ideological forces. Using the insights from the scholarship on nation-building and gender, this paper explores the official (government’s) narrative on women in Tajikistan. Based on content analysis of various primary data sources, including official documents, government publications, official speeches, and media sources, I argue that contemporary nation-building has become about tangible lifestyles. Thus, nationhood in Tajikistan has acquired a recognizably gendered character. In this state-promoted imagination, women encapsulate the Tajik nation by performing three significant tasks that continuously reproduce and represent the nation: they bear, rear, and wear the Tajik nation-state.
Online Male Sex Work in Kazakhstan: A Distinct Market?
Authors: Thibault Hélène
Published: August 2022

In this article, I explore male sex-work in Kazakhstan and show that unlike male sex work around the world, the Kazakhstani market appears to be overwhelmingly heterosexual. Based on a sample of 200 online advertisements, this paper generates original data by providing an overview of male sex work in Kazakhstan’s two largest cities, Almaty and Nur-Sultan. This data is analyzed through a gender lens that acknowledges a shift in local gender roles and expectations and I argue that a desire for sexual emancipation, which is constrained by conservative views surrounding female sexuality explains this particular phenomenon. More precisely, I suggest that women are likely to have discreet sex with anonymous professionals rather than indulge in casual sex with strangers or acquaintances to maintain their reputation. While most gender research in Central Asia focuses on issues of re-traditionalization, this article investigates women’s sexuality and desires in Kazakhstan outside of the re-traditionalization paradigm.
Non-formal and dual education in Ukraine
Authors: Viter Mykhailo , Derzhuk Olena
Published: August 2022

The article substantiates the process of implementation and recognition of the education, which provides educational process outside the formal education system in Ukraine. It is shown that, along with formal education, knowledge and relevant qualifications can be acquired through non-formal and informal education. These types of education become significant nowadays due to the dynamics of market needs, which often require promptly changing of professional qualification. The authors of the article present the measures taken by the Government of Ukraine, which are aimed at the development of the new educational paradigm in the country, including: the development of relevant normative documents, the formation of the register of qualifications, and the establishment of the network of qualification centers, which will assign professional qualifications outside formal educational institutions. They present the definitions of the concepts of formal education, non-formal education, informal education, educational qualification, professional qualification, and competence in accordance with their interpretation specified in the regulations of the Government of Ukraine. Special attention is paid to the analysis of the current state and the perspectives in the development of dual form of education in Ukraine. Based on the experience of Germany and other European countries, the authors substantiate the relevancy and feasibility of dual education in Ukraine. They demonstrate as the examples of successful implementation of dual education the cases of the National Technical University of Ukraine “Kyiv Polytechnic Institute named after Igor Sikorskyˮ and the University of State Fiscal Service of Ukraine. The advantages and disadvantages of the dual form of education are described. The main reasons for the low rate of implementation of these types of education in Ukraine are indicated. Keywords: education, non-formal education, dual education, qualification, competency.
Artistic educational competence of future primary school teachers: essence, components, ways of formation
Authors: Kovalchuk Larysa , Yavorska Khrystyna
Published: August 2022

The article considers the issue of the development of artistic educational competence, which is relevant due to the educational reform the New Ukrainian school, and the introduction of the State Standard of Primary Education, that led to the changes not only in the approaches to teaching in primary education, but also in the professional training of future primary school teachers. On the basis of analysis of academic and pedagogical literary sources, the authors of the article present the meaning of the notions «competence», «cultural competence» and «artistic competence», and specify the essence of the concepts «cultural competence of primary school students» and «artistic educational competence of the future primary school teachers». The components of artistic educational competence (artistic and pedagogical knowledge; artistic and pedagogical skills and abilities; values and attitudes; experience of creative activity; professional and pedagogical abilities and personal qualities) are distinguished and characterized. The artistic educational competence of the future primary school teachers is defined as a combination of these components and the ability to apply them in practical/professional activities. The ways of formation of artistic educational competence of the future primary school teachers are given. It is determined that the artistic educational competence of the future primary school teachers is shaped during the students’ mastering educational components (academic disciplines, term papers, internships) in higher education institutions. It is noted that self-education and self-development are important factors in the development of the artistic educational competence, which ensures the readiness of future primary school teachers to develop the cultural competence of primary school students. Keywords: competence, cultural competence, students of primary education, artistic competence, artistic educational competence, artistic education, future primary school teachers.
The Influence of Self-Efficacy in Mediated Individual Characteristics on Leadership Learning Performance in PT X
Authors: Rahmat Tasnim RahmatTasnim
Published: August 2022

The achievement of learning performance can create benefits for a company both in increasing employee competence and company productivity. The cost spent, however, is usually not proportional to the graduation rate and returns on the company. Self-efficacy is a performance predictor. Individual characteristics have a strong role in the effectiveness of learning. This research aims to test the role of individual characteristics in  leadership learning performance with self-efficacy as a mediator variable. The data in this study are secondary data owned by PT X. This data were processed by parallel mediation analysis model using Macro PROCESS and SPSS software. The results showed that self-efficacy is able to mediate the role of individual characteristics in leadership learning performance. This research found that self-efficacy and continuous learning ability were able to partially mediate the role of individual characteristics in leadership learning performance. Thus, by adding indirect effect of mediator variable, it can further enhance the role of individual characteristics in leadership learning performance.

Tercapainya kinerja pembelajaran dapat memberikan manfaat bagi perusahaan baik dalam peningkatan kompetensi karyawan maupun produktivitas perusahaan. Biaya yang dikeluarkan, bagaimanapun, biasanya tidak sebanding dengan tingkat kelulusan dan pengembalian perusahaan. Self-efficacy adalah prediktor kinerja. Karakteristik individu memiliki peran yang kuat dalam efektivitas pembelajaran. Penelitian ini bertujuan untuk menguji peran karakteristik individu dalam kinerja pembelajaran kepemimpinan dengan efikasi diri sebagai variabel mediator. Data dalam penelitian ini adalah data sekunder milik PT X. Data ini diolah dengan model analisis mediasi paralel menggunakan software Macro PROCESS dan SPSS. Hasil penelitian menunjukkan bahwa efikasi diri mampu memediasi peran karakteristik individu dalam kinerja pembelajaran kepemimpinan. Penelitian ini menemukan bahwa efikasi diri dan kemampuan belajar berkelanjutan secara parsial mampu memediasi peran karakteristik individu dalam kinerja pembelajaran kepemimpinan. Dengan demikian, dengan menambahkan pengaruh tidak langsung dari variabel mediator dapat lebih meningkatkan peran karakteristik individu dalam kinerja pembelajaran kepemimpinan.

 
Perancangan Sistem Monitoring Gangguan Traksi Motor pada Lokomotif Cc 201/203 Berbasis IoT di Depo Induk Sidotopo Surabaya
Authors: Prasetyo Kusuma Aji , Hartayu Ratna , Basyarach Niken Adriaty , W Izzah Aula
Published: August 2022

Pengecekan kondisi kesalahan pada taksi motor lokomotif seri CC 201 dan CC 203 apabila terjadi gangguan saat ini tidak dapat terdeteksi secara otomatis, sehingga apabila terjadi gangguan pada traksi motor, pengecekan untuk perbaikannya masih manual dengan cara pekerja tenaga perawatan harus mencari terlebih dahulu traksi motor mana yang mengalami gangguan dengan melihat pada kondisi traksi motor satu per satu, hali ini dirasa kurang efesien, dan membutuhkan waktu yang lama. Berdasarkan permasalahan diatas,dibutuhkan suatu alat untuk melakukan pembacaan kesalahan arus pada masing – masing traksi motor lokomotif CC 201/ CC 203 agar dapat mempercepat proses pendeteksian terjadinya gangguan pada traksi motor. Tugas akhir ini berupa aplikasi yang dapat menampilkan kondisi arus pada 3 traksi motor lokomotif CC 201/ CC 203  melalui aplikasi blynk. Alat ini menggunakan LEM HTC 1000 sebagai sensor arus, NodeMCU ESP32 sebagai pengolah data, dan aplikasi blynk untuk menampilkan hasil pembacaan serta notifikasi adanya gangguan. Pada pengujian sistem, dilakukan dengan cara membandingkan hasil pembacaan alat yang telah dibuat dengan hasil pembacaan secara manual menggunakan tang ampere, kemudian nilai arus pada masing – masing traksi motor selalu ditampilkan pada aplikasi blynk sehingga ketika ada gangguan pada salah satu traksi motor akan kemudian ditampilkan notifikasi berisi pada traksi motor ke berapa yang sedang mengalami gangguan besera nilai arusnya. Dari pengujian tersebut untuk sistem monitoring deteksi gangguan traksi motor dapat berjalan dengan baik dengan tampilan arus tiap – tiap traksi motor dapat diketahui melalui aplikasi blynk begitu pula pada saat adanya gangguan. Untuk kestabilan monitoring tersebut dalam melakukan pembacaan juga dirasa cukup baik dengan waktu realtime dengan selisih pengukuran dalam 10 kali percobaan didapatkan selisih kecepatan pembacaan tidak lebih dari 1 detik sehingga alat dapat memberikan informasi di traksi motor mana yang sedang terjadi gangguan dengan notifikasi pada aplikasi blynk dengan cepat.
Sistem Multiproteksi Pencegahan Dini Deteksi Kebakaran Berbasis Atmega16
Authors: Putra Affandy Nazar , Ridhoi Achmad , Santoso Santoso , Hariadi Balok , Slamet Puji
Published: August 2022

Kebakaran merupakan hal yang sangat sering terjadi terutama pada rumah yang ditinggal pergi oleh pengghuninya, hal ini akan diperparah karena ketika terjadi kebakaran pada rumah kosong intensitas api pada saat diketahui sudah sulit ditanggulangi. Untuk itu pada proyek akhir ini dirancanglah suatu system peringatan dini deteksi kebakaran berserta penanggulangan dini yang dapat membantu dan menginformasikan kepada user/pemilik rumah ketika terjadi indikasi kebakaran atau terdapat sumber gas (elpiji) dalam intensitas yang masih kecil dengan system multiproteksi yakni penginformasian setiap terdapat indikasi api atau gas yang berpotensi menyebabkan kebakaran sehingga memungkinkan user/pemilik rumah untuk melakukan tindakan berikutnya untuk menanggulangi/mencegah membesarnya kondisi api atau gas
Implementasi Lean Manufacturing untuk Mengurangi Waste pada Produksi Pivot Piece (Studi Kasus PT. Tri Jaya Teknik Karawang)
Authors: Farida Muthia Elsa , Azizah Fahriza Nurul , Hamdani Hamdani
Published: August 2022

PT Tri Jaya Teknik Karawang is one of the manufacturing companies engaged in the production of vehicle parts, because its main product is pivot piece. As for other forms of products produced by this company, such as Gongsol and Fuji Seat. This product research at PT Tri Jaya Teknik Karawang will be carried out on one type of Piece Pivot product, because this product is the company's main product, whose regular demand every month is always there and the amount is uncertain. This company has waste in the production line, namely the existence of product defects and lead times. This study aims to determine the types of waste and what factors occur in the production of pivot pieces at PT. Tri Jaya Engineering Karawang. By using the Lean Manufacturing method which begins with creating a Value Stream Mapping (VSM) then performs an analysis using the Failure Mode and Effects Analysis (FMEA) method. It is known that in the production of pivot pieces there are 3 types of waste identified, namely waiting time, unnecessary waste of inventory, and product defects. Proposed improvements to minimize waste in the production of pivot pieces are to carry out regular machine maintenance, create a production flow and provide warnings and evaluations of the performance of production operators.
Misdiagnosis of epithelioid trophoblastic tumors: a case report and literature review
Authors: Zhou Tao , Ying Jun , Feng Jiawen , Wu Weiqiang , Ye Peng , Shi Jie , Wan Qihong , Qian Jianhua
Published: August 2022

Background: The most common clinical types of gestational trophoblastic neoplasia are invasive hydatidiform mole and choriocarcinoma, which can be diagnosed without pathology, and be cured by chemotherapy. Epithelial trophoblastic tumor, a rare type of gestational trophoblastic neoplasia, does not exhibit precise clinical manifestations upon auxiliary examinations. Therefore, since epithelial trophoblastic tumors are prone to misdiagnoses and missed diagnoses, their diagnosis have to be confirmed through pathology and immunohistochemistry. Case: We describe a case of a 37-year-old woman that had been misdiagnosed at a local hospital after she had presented with irregular vaginal bleeding and elevated human chorionic gonadotropin. The initial diagnosis was ectopic pregnancy and she was subjected to left salpingectomy, however, after treatment, there was no significant drop in human chorionic gonadotropin. Later, she was diagnosed with gestational trophoblastic neoplasia and was treated with multiple chemotherapy and hysterectomy. However, after treatment, her human chorionic gonadotropin was found to repeatedly fluctuate. Eventually, pathological examination of a resected lung lesion confirmed the presence of epithelial trophoblastic tumors. Conclusions: Epithelial trophoblastic tumor is an intermediate trophoblastic tumor that is not sensitive to conventional chemotherapy. Surgical resection is the recommended therapeutic option. Gestational trophoblastic neoplasia patients presenting with persistently low levels of human chorionic gonadotropin and resistance to conventional chemotherapy should, therefore, be considered for early surgical resection, or tissue biopsy to pathologically confirm the diagnosis and inform treatment options.
Genome-Wide Identification, Expression and Interaction Analysis of ARF and AUX/IAA Gene Family in Soybean
Authors: Ali Shahid , Wang Wanpeng , Zhang Zhaohan , Xie Linan , Boer D. Roeland , Khan Naeem
Published: August 2022

Background: The plant hormones auxin affects most aspects of plant growth and development. The auxin transport and signaling are regulated by different factors that modulate plant morphogenesis and respond to external environments. The modulation of gene expression by Auxin Response Factors (ARFs) and inhibiting Auxin/Indole-3-Acetic Acid (Aux/IAA) proteins are involved in auxin signaling pathways. These components are encoded by gene families with numerous members in most flowering plants. Methods: However, there is no genome-wide analysis of the expression profile and the structural and functional properties of the ARF and Aux/IAA gene families in soybean. Using various online tools to acquire of genomic and expression data, and analyzing them to differentiate the selected gene family’s expression, interaction, and responses in plant growth and development. Results: Here, we discovered 63 GmIAAs and 51 GmARFs in a genome-wide search for soybean and analyzed the genomic, sequential and structural properties of GmARFs and GmIAAs. All of the GmARFs found have the signature B3 DNA-binding (B3) and ARF (Aux rep) domains, with only 23 possessing the C-terminal PB1 (Phox and Bem1) domain (Aux/IAA), according to domain analysis. The number of exons in GmARFs and GmIAAs genes varies from two to sixteen, indicating that the gene structure of GmARFs and GmIAAs is highly variable. Based on phylogenetic analysis, the 51 GmARFs and 63 GmIAAs were classified into I–V and I–VII groups. The expression pattern of GmARFs and GmIAAs revealed that the GmARF expression is more specific to a particular part of the plant; for example, ARF 2, 7, and 11 are highly expressed in the root. In contrast, GmIAAs expression has occurred in various parts of the plants. The interaction of ARF with functional genes showed extensive interactions with genes involved in auxin transport which helps to control plant growth and development. Furthermore, we also elaborate on the DNA-protein interaction of ARFs by identifying the residues involved in DNA recognition. Conclusions: This study will improve our understanding of the auxin signaling system and its regulatory role in plant growth and development.
Coronary Artery Disease and Revascularization in Patients Undergoing Transcatheter Aortic Valve Replacement
Authors: Garg Aakash , Ilyas Suleman , Cryer Michael , Abbott J. Dawn
Published: August 2022

Coronary artery disease (CAD) and aortic stenosis share similar risk factors and underlying pathophysiology. Up to half of the patient population undergoing work-up for aortic valve replacement have underlying CAD, which can affect outcomes in patients with more severe disease. As the indications for transcatheter aortic valve replacement (TAVR) have expanded to intermediate and now low risk patients, the optimal management of CAD in this patient population still needs to be determined. This includes both pre-TAVR evaluation for CAD as well as indications for revascularization in patients undergoing TAVR. There is also limited data on coronary interventions after TAVR, including the incidence, feasibility and outcomes of patients undergoing percutaneous coronary intervention (PCI) after TAVR. This review provides an updated report of the current literature on CAD in TAVR patients, focusing on its prevalence, impact on outcomes, timing of revascularization and potential challenges with coronary interventions post-TAVR.
Longer Hospitalizations and Higher In-Hospital Mortality for Acute Heart Failure during the COVID-19 Pandemic in Larger vs. Smaller Cardiology Departments: Subanalysis of the COV-HF-SIRIO 6 Multicenter Study
Authors: Ostrowska Małgorzata , Kasprzak Michał , Stolarek Wioleta , Grzelakowska Klaudyna , Kryś Jacek , Kubica Aldona , Adamski Piotr , Podhajski Przemysław , Navarese Eliano Pio , Anielska-Michalak Edyta , Matuszewska-Brycht Oliwia , Curzytek Andrzej , Dudek Aneta , Gromadziński Leszek , Grzelakowski Paweł , Kamiński Leszek , Kleinrok Andrzej , Kostkiewicz Marcin , Koziński Marek , Król Paweł , Kulawik Tomasz , Minczew Gleb , Mindykowski Marcin , Pawlak Agnieszka , Prokopczuk Janusz , Skonieczny Grzegorz , Sobkowicz Bożena , Sowiński Sergiusz , Stankala Sebastian , Szymański Paweł , Wester Andrzej , Wilczewski Przemysław , Bartuś Stanisław , Budaj Andrzej , Gajda Robert , Gąsior Mariusz , Gruchała Marcin , Drożdż Jarosław , Jaguszewski Miłosz , Jankowski Piotr , Legutko Jacek , Lesiak Maciej , Leszek Przemysław , Mitkowski Przemysław , Nessler Jadwiga , Tomaszuk-Kazberuk Anna , Tycińska Agnieszka , Zdrojewski Tomasz , Kaźmierczak Jarosław , Kubica Jacek
Published: August 2022

Background: The coronavirus disease-2019 (COVID-19) pandemic is surging across Poland, leading to many direct deaths and underestimated collateral damage. We aimed to compare the influence of the COVID-19 pandemic on hospital admissions and in-hospital mortality in larger vs. smaller cardiology departments (i.e., with ≥2000 vs. <2000 hospitalizations per year in 2019). Methods: We performed a subanalysis of the COV-HF-SIRIO 6 multicenter retrospective study including all patients hospitalized in 24 cardiology departments in Poland between January 1, 2019 and December 31, 2020, focusing on patients with acute heart failure (AHF) and COVID-19. Results: Total number of hospitalizations was reduced by 29.2% in larger cardiology departments and by 27.3% in smaller cardiology departments in 2020 vs. 2019. While hospitalizations for AHF were reduced by 21.8% and 25.1%, respectively. The length of hospital stay due to AHF in 2020 was 9.6 days in larger cardiology departments and 6.6 days in smaller departments (p < 0.001). In-hospital mortality for AHF during the COVID-19 pandemic was significantly higher in larger vs. smaller cardiology departments (10.7% vs. 3.2%; p < 0.001). In-hospital mortality for concomitant AHF and COVID-19 was extremely high in larger and smaller cardiology departments accounting for 31.3% vs. 31.6%, respectively. Conclusions: During the COVID-19 pandemic longer hospitalizations and higher in-hospital mortality for AHF were observed in larger vs. smaller cardiology departments. Reduced hospital admissions and extremely high in-hospital mortality for concomitant AHF and COVID-19 were noted regardless of department size.
Optimization of High Concentration Plasmid DNA for Use in COVID-19 mRNA Vaccine Development: Comparison of Between Alkaline Lysis Method and Commercial Kit Results
Authors: Duran Tuğçe , Çine Naci , Koçak Nadir , Kurt Saliha
Published: August 2022

While forming the stable IVT mRNA molecule, high concentration and purity plasmid DNA must be obtained to ligase the ORF antigen sequence initially copied from the plasmid DNA with the UTR regions. In this study, in the stage of creating the mRNA molecule, which is the first step of the COVID-19 mRNA vaccine, comparison and optimization of the pDNA containing the ORF target antigen sequence were performed as a result of isolation with alkaline lysis method and commercial kit. Plasmid DNA bacteria containing the target antigen ORF sequence were grown under appropriate conditions. Plasmid DNA was isolated by commercial kit and alkaline lysis method from bacterial cultures stopped at different OD600 nm values (0.02-0.05, 0.05-0.1, 0.1-0.2, 0.2-0.3, 0.3-0.4, 0.4-0.5). After the obtained pDNAs were visualized on an agarose gel, their purity and concentration were measured by spectroscopic measurement. After the stab culture is resuscitated in SOC medium, bands are formed in a single form after isolation with the kit, and in multiple forms (linear, supercoiled, circular) after pDNA isolation by alkaline lysis method. The ideal OD600 nm for both methods was 0.3-0.4. As a result of isolation with the kit, higher purity on the contrary low concentration pDNA was obtained. The ideal OD600 nm value is a critical parameter that affects the concentration and purity of pDNA. The alkaline lysis method is a cheap and powerful technique that can be used as an alternative for mRNA vaccine development compared to kit isolation.