bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost-effectiveness analysis of denosumab versus alendronate for improving bone mineral density in renal transplant recipients: a comparative study
Authors: Alshahawey Mona , Shawki May A , Sayed Sherihan Ahmed , Elseasi Ahmad , ElWakeel Lamia
Published: October 2024

Background

Denosumab and alendronate had a positive impact on bone mineral density (BMD) preservation after kidney transplantation. However, the cost-effectiveness of these agents in the context of kidney transplantation remains largely unexplored. We have conducted a cost-effectiveness analysis to compare the cost and the clinical outcomes of adding subcutaneous (SC) 60 mg denosumab every 6 months vs. oral weekly 70 mg Alendronate, to the standard care therapy (vitamin D and calcium) in renal transplant recipients (RTRs). The impact of both drugs on BMD t-score improvement and fracture prevention was investigated. A decision-analysis model from a health care payer perspective was applied.

Results

The cost-effectiveness analysis has shown that alendronate add-on to the standard therapy was the most cost-effective regimen, in terms of BMD improvement and fracture prevention with an incremental cost-effectiveness ratio (ICER) of $154/patient/year. The one-way sensitivity analyses have delineated the change in cost-effectiveness when alendronate retail unit price was increased by 25% and 50%, or when denosumab retail unit price was decreased by 25% and 50%. The model was sensitive to the uncertainties (95% confidence interval) in the probabilities of fracture prevention and the probabilities of attaining the desired outcome.

Conclusion

The model suggests that oral once weekly alendronate add-on regimen to standard therapy seems to be substantially more cost effective than twice yearly SC denosumab in terms of BMD improvement and fracture prevention in RTRs. Longer time horizon models with longer follow-up periods for fracture risks and adverse events are warranted to validate these data.
Upper airway obstruction patterns among non-obese individuals with snoring and obstructive sleep apnea
Authors: Aref Essam Eldin M. , Mohammed Basma Khairy , Magdy Doaa M. , Ibrahim Reham A.
Published: October 2024

Background

Snoring is an inspiratory noise due to partialobstruction of the upper airways. It is commonly linked to a sleep problem known as obstructive sleep apnea (OSA). The clinical criteria of OSA in non-obese patients are distinct and warrant more investigation, despite being well-studied in the obese population.

Objective

The aim of this study is to provide a diagnostic profile of snoring and OSA in non-obese patients using various assessment tools in order to identify upper airway obstruction patterns and potential risk factors in these patients to improve their management and prevent related comorbidities.

Methodology

An observational cross-sectional study of 30 non-obese (BMI < 29.9) snorers (18 males and 12 females) with a mean age of 38.13 ± 8.4 years. All patients underwent polysomnography and thorough clinical examination, including searching for possible risk factors/co-morbidity, Epworth Sleepiness Score (ESS), Mallampati score, awake upper airway endoscopy combined with Muller maneuver, and drug-induced sleep endoscopy (DISE).

Results

OSA presented in 80% of our patients, the age range of 17–58 years, apnea–hypopnea index (AHI) mean 20.63 ± 17.8 event/h, and its severity was mild 7 (23.3%), moderate 6 (20%), and severe 11 (36.7%). Findings of oral and nasal examination showed no association with AHI. Also, sleep endoscopy findings regarding specific structures causing upper airway obstruction showed no significant association. A positive correlation was found between the extent of retropalatal airway collapse and AHI. A notable association was found between smoking and AHI as a risk factor for OSA in non-obese individuals. No significant relationship was found between ESS, concomitant diseases, and AHI.

Conclusion

OSA is common in non-obese patients and probably may be attributed to retropalatal/oropharyngeal airway collapse and associated with smoking as a risk factor. Further studies are warranted to reveal other pathophysiological aspects in this group of patients.
Mineral imbalance and cardiovascular disease in animals of the canine (Canidae) and feline (Felidae) families: a study in Russian zoos
Authors: Zaitsev Sergei Yu. , Stepanova Marina V. , Sotnikova Larisa F.
Published: October 2024

It is important to consider the full spectrum of complex interactions between mineral elements and biologically active substances to evaluate the development of cardiovascular disease (CVD) in animals, in addition to the classical physiological approach. This study aimed to assess changes in mineral element levels in wild and exotic animals in relation to their cardiovascular diseases. A total of 171 animals, including 128 healthy and 43 sick animals from three Russian zoos, were sampled and analyzed. For the first time, species from the canine (nine) and feline (seven) families from Moscow, Ivanovo, and Yaroslavl zoos in the Central Federal District of Russia were selected. A total of 108 samples from canines and 63 samples from feline animals were collected. Mineral element measurements were conducted on 1026 samples via a "Kvant-2A" atomic absorption spectrometer from Russia. Correlation and regression analyses were performed. CVDs were found in 10.1% of the studied animals, with a high percentage of heart muscle pathologies noted (25.8% of all CVDs). Iron (Fe) accumulated in canine and feline fur at approximately 208 and 203 mg/kg, with variations of 72.8% and 80.9%, respectively. A significant decrease in Fe and an increase in cadmium (Cd) during CVD were observed (correlations r = 0.25 and r = 0.16, respectively). The dysregulation of Fe homeostasis, increased absorption, and accumulation of Fe in the reticuloendothelial system are discussed. Finally, the mineral elements absorbed by canine and feline fur can be ranked in descending order: Fe > Zn > Cu > Pb > Cd > As.
Effect of Mutation Type on Ectopic Ossification Among Adult Patients With X-Linked Hypophosphatemia
Authors: Kato Hajime , Ishihara Yasuki , Ohata Yasuhisa , Irie Koki , Watanabe So , Kimura Soichiro , Hoshino Yoshitomo , Hidaka Naoko , Kinoshita Yuka , Taniguchi Yuki , Kobayashi Hiroshi , Braddock Demetrios T , Kubota Takuo , Ozono Keiichi , Nangaku Masaomi , Makita Noriko , Ito Nobuaki
Published: October 2024

Context

Causative factors for ectopic ossifications in X-linked hypophosphatemia (XLH) remain to be elucidated.

Objective

This work aimed to investigate the genotype-phenotype correlations between the phosphate-regulating endopeptidase homologue, X-linked gene (PHEX) and ectopic ossifications in XLH.

Methods

Biochemical data, spinal computed tomography scans, and x-rays of hip/knee joints were retrospectively reviewed. Genetic analysis and the measurement of plasma inorganic pyrophosphate (PPi)—a potent inhibitor of tissue calcification—were performed. The effect of PHEX mutations on protein function was predicted using nonsense-mediated decay (NMD) and 3-dimensional structure modeling. The index of ossification of the anterior/posterior longitudinal ligament and yellow ligament (OA/OP/OY index) and the sum of the OA/OP/OY index (OS index) were used to quantify the severity of spinal ligament ossification. The severity of the hip/knee osteoarthritis was evaluated by the Kellgren-Lawrence classification.

Results

We examined 24 distinct pathogenic PHEX variants in 28 patients from a study population of 33 individuals in 27 unrelated, nonconsanguineous families. Among the 31 patients whose plasma samples were analyzed for PPi, 14 patients (45%) showed decreased plasma PPi concentrations; however, PPi concentrations did not correlate with mutation type or ectopic ossification. Fibroblast growth factor 23 levels in women with NMD-insensitive mutations trended lower than in men with NMD-sensitive mutations but failed to reach statistical significance. Both models revealed no correlations between PHEX pathogenic variant and ectopic ossification.

Conclusion

Neither modeling found correlates between PHEX pathogenic variants and ectopic ossification. The effects of PPi on ectopic ossifications in adults with XLH revealed trends that should be investigated with a large sample size.
Real-Time Ultrasonography for the Placement of Caudal Epidurals for Thoracic Surgery in Infants: A Description of the Technique and Case Series
Authors: Varman Mithun A. , VV Subramanian , R. Sripriya , Asha Kundrapu
Published: October 2024

Caudal epidural catheters threaded to the thoracic levels are increasingly utilized in infants undergoing thoracic and abdominal surgery, compared to lumbar or thoracic epidural techniques. Estimating catheter length traditionally relies on anatomical landmarks, but the lack of spine ossification in infants makes ultrasonography a valuable and noninvasive tool. We present 3 cases where real-time ultrasonography facilitated caudal to thoracic epidural catheter placement in infants undergoing thoraco-abdominal surgeries. Incision-congruent placement of the catheter tip ensured effective perioperative analgesia with low doses of bupivacaine administered as intermittent boluses resulting in potent and prolonged analgesia with reduced opioid requirements.
“But on Sunday, They Are Free”
Authors: Dela Cruz Ariel M.
Published: October 2024

This article examines the site of the home in Baby Ruth Villarama's 2016 documentary Sunday Beauty Queen to better understand how tomboy migrant domestic workers in Hong Kong mess up and queer domesticity. By focusing on the appearances in the film of the home of Leo Selomenio, a tomboy Filipino migrant domestic helper and organizer of Sunday beauty pageants, the author explores alternative modes of care performed by tomboys that refuse respectability politics as they operate within transnational migrant labor structures. Despite the regulatory and confining modes of racialized and gendered care that structure global care work, Selomenio reconfigures and reshapes his home to operate as a site of refuge, an archive, a gathering space, and a site of resistance. Engaging in what the author terms “tomboy domesticity,” Selomenio utilizes his control over home space and time as a result of his exemption from the live-in requirement of his work to ensure collective survival in the face of labor precarity. Selomenio's performance of care ethics that refuse the state's neglect of domestic helpers articulates tomboy and diasporic Filipino life as valuable outside of its capacity to labor.
The efficacy of hemoglobin spray in wound management: a systematic review and network meta-analysis of comparative studies
Authors: Wilasrusmee Chumpon , Supsamutchai Chairat , Pornwaragorn Chaowanun , Jirasiritham Jakrapan , Poprom Napaphat
Published: October 2024

Purpose There is no evidence comparing the treatment results of hemoglobin spray and hyperbaric oxygen therapy (HBOT) in chronic wounds. Therefore, we conducted a systematic review and network meta-analysis to explore the efficacy and role of hemoglobin spray in the treatment of chronic wounds. The probabilities of being the best treatment option were estimated and ranked between hemoglobin spray and HBOT. Methods A systematic review and network meta-analysis (NMA) were conducted according to the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines and PROSPERO number: CRD42020161396. Results A total of 934 studies were identified from PUBMED and SCOPUS databases, and 112 articles were deleted. Among the 24 studies, 16 RCTs and eight cohort studies met our inclusion criteria. In direct meta-analysis, HBOT had higher proportion of wound healing rate than control with pooled risk ratios (RRs) of 1.67 (95%CI: 1.10, 2.52). Hemoglobin spray had a higher wound healing rate than the control, with a pooled odds ratio (OR) of 1.92 (95%CI: 1.35, 2.73). In the network meta-analysis, the probability of being the best treatment was hemoglobin spray, followed by hyperbaric, with surface under the cumulative ranking curve (SUCRAs) of 67.9, and 32.1, respectively. Conclusions Our evidence suggests that the proportion of wound healing in the hemoglobin spray and HBOT groups was higher than that in the control group. A network meta-analysis demonstrated that hemoglobin spray had the highest chance of treatment success. There is a need for further studies using well-designed RCTs and updated meta-analyses to provide enough evidence to compare the effectiveness of hemoglobin spray and HBOT in clinical practice.
Transcutaneous stimulation as a niche theme in gastroparesis therapy
Authors: SALEH ARMAN YURISALDI , Valentina Riezky , Saputra Dwi Arwandi Yogi
Published: October 2024

Introduction Gastroparesis, a global condition causing bile salt accumulation, is prevalent globally. Diagnosis techniques like bile salt titration and nitric oxide sulfate can improve patient care. However, simptomatic control is needed to reduce inflammation and control potential diseases. Neurological techniques like gyroscope stimulation and endoscopy can diagnose refractive gastroparesis. Interdisciplinary collaboration and bibliometric research are crucial for finding effective treatments. Gastroparesis, a motility issue affecting 0.9-1.3% of diabetics, can be improved by new diagnostic methods like osmotic pressure and gastric emptying, enhancing patient treatment. Methods This study uses a literature review methodology to gather data from the Scopus database on neuroaid, analyzing it using Biblioshiny and VOSviewer software. The focus is on dietary adjustments, glucose regulation, and transcutaneous stimulation’s role in gastroparesis treatment, using quantitative and qualitative analysis. Results The research trend found are documents by year, most relevant sources, factorial map of the most cited documents, factorial map of The documents with the highest contributes, documents by author, documents by country or territory, documents by subject area, documents by affiliation, network visualization, overlay visualization of scopus database using vosviewer, density visualization, thematic map, thematic evolution, cluster analysis, topic dendogram, and country collaboration map. According to our analysis, transcutaneous stimulation holds great promise for treating gastroparesis. We also found the necessity of multidisciplinary collaboration in the management of this illness. Conclusions The study on gastroparesis highlights key themes like diet modification, glucose control, medication therapy, Cajal’s role in smooth muscle concentration, common causes, transcutaneous stimulation, motorcycle themes, vagus nerve, and emerging devices and electronics. Basic themes include gastrointestinal disorders, neuromodulation, patients, diabetes, and gastric electrical stimulation. The management of gastroparesis involves multidisciplinary approaches, lifestyle changes, medication therapy, and bedtime interventions, with further investigation into transcutaneous stimulation being warranted.
Chlorophyll-a determinations in mesocosms under varying nutrient and temperature treatments: in-situ fluorescence sensors versus in-vitro measurements
Authors: Levi Eti Ester , Jeppesen Erik , Nejstgaard Jens C. , Davidson Thomas Alexander
Published: October 2024

Harmful algal blooms (HABs) are a significant threat to freshwater ecosystems, and monitoring for changes in biomass is therefore important. Fluorescence in-situ sensors enable rapid and high frequency real-time data collection and have been widely used to determine chlorophyll-a (Chla) concentrations that are used as an indicator of the total algal biomass. However, conversion of fluorescence to equivalent Chla concentrations is often complicated due to biofouling, phytoplankton composition and the type of equipment used. Here, we validated measurements from 24 Chla and 12 phycocyanin (cyanobacteria indicator) fluorescence in-situ sensors (Cyclops-7F, Turner Designs) against spectrophotometrically (in-vitro) determined Chla and tested a data-cleaning procedure for eliminating data errors and impacts of non-photochemical quenching. The test was done across a range of freshwater plankton communities in 24 mesocosms (i.e. experimental tanks) with a 2x3 (high and low nutrient x ambient, IPCC-A2 and IPCC-A2+50% temperature scenarios) factorial design. For most mesocosms (tanks), we found accurate (r2 ≥ 0.7) calibration of in-situ Chla fluorescence data using simple linear regression. An exception was tanks with high in-situ phycocyanin fluorescence, for which multiple regressions were employed, which increased the explained variance by >16%. Another exception was the low Chla concentration tanks (r2 < 0.3). Our results also show that the high frequency in-situ fluorescence data recorded the timing of sudden Chla variations, while less frequent in-vitro sampling sometimes missed these or, when recorded, the duration of changes was inaccurately determined. Fluorescence in-situ sensors are particularly useful to detect and quantify sudden phytoplankton biomass variations through high frequency measurements, especially when using appropriate data-cleaning methods and accounting for factors that can impact the fluorescence readings. Nevertheless, corroborating these data with in-vitro Chla assessments would provide additional validation for the early warnings provided by sensor data.
Oriented artificial nanofibers and laser induced periodic surface structures as substrates for Schwann cells alignment
Authors: Lifka Sebastian , Plamadeala Cristina , Weth Agnes , Heitz Johannes , Baumgartner Werner
Published: October 2024

People with injuries to the peripheral nervous system suffer from paralysis of the facial muscles, fingers and hands or toes and feet, often for the rest of their lives, due to its poor functional regeneration. Therefore, to improve patients’ quality of life, there is an urgent need for conduits that effectively support the healing of large defects in nerve pathways through specific guidance of nerve cells. This paper describes two specific methods for achieving directed growth of Schwann cells, a type of glial cells that can support the regeneration of the nerve pathway by guiding the neuronal axons in the direction of their alignment. One method uses aligned polyamide-6 (PA-6) nanofibers produced via electrospinning on a very fast rotating structured collector, which enables easy nanofiber detachment, without additional effort. The other method implies the exposure of a poly(ethylene terephthalate) (PET) foil to a KrF* laser beam, that renders a nanorippled surface topography. Schwann cell growth on these substrates was inspected after one week of cultivation by means of scanning electron microscopy (SEM). For both methods we show that Schwann cells grow in a certain direction, predetermined by nanofiber and nanoripple orientation. In contrast, cells cultivated on randomly oriented nanofibers or unstructured surfaces, show an omnidirectional growth behavior. These two methods can be used to produce nerve conduits for the treatment of injuries to the peripheral nervous system.
Niewolni w późnośredniowiecznych Prusach
Authors: Kwiatkowski Krzysztof
Published: October 2024

W artykule został podjęty temat jeńców wojennych z ziem żmudzkich, litewskich i czarnoruskich uprowadzonych przez wojska pruskiej gałęzi zakonu niemieckiego podczas tak zwanej wojny litewskiej w latach 1283–1406. Przeprowadzona analiza szerokiej bazy źródłowej pozwoliła ustalić, że jeńcy zostali wzięci do niewoli w trakcie 118 przedsięwzięć militarnych Zakonu przeciwko Litwie. Dla 77 wypraw można było ustalić ich liczbę (w zależności od źródeł od 33 404 do 40 343 osób). Uwzględnienie tych danych, uzupełnionych o szacunki oparte na ekstrapolacjach dotyczących pozostałych 41 oraz kolejnych 108 wypraw, dało łączny szacunek około od 72 591 do 118 419 osób uprowadzonych do Prus w tym okresie. Liczby te pokazują realną skalę przymusowego przepływu ludności z obszarów podlegających władzy książąt litewskich do Prus w latach 1283–1406.
Geschichte der Debatten um Lohnarbeit, Sklaverei und die Triebkräfte hinter dem Kapitalismus
Authors: Yazdani Kaveh
Published: October 2024

Inwiefern ist die Unterscheidung zwischen freien und unfreien Arbeitsverhältnissen im Hinblick auf die Geschichte und Dynamik des Kapitalismus sinnvoll? Anhand einer kursorischen Untersuchung und Analyse, insbesondere deutschsprachiger Diskurse über Sklaverei und (freie) Lohnarbeit seit dem späten 18. Jahrhundert, wird ein erster Versuch unternommen, diese Frage vor dem Hintergrund einiger englisch- und französischsprachiger Beiträge der letzten 300 Jahre zu erörtern und zu kontextualisieren.
Stosowanie aresztu prewencyjnego (Schutzhaft) na ziemiach okupowanej Polski na przykładzie Akcji „Inteligencja” w okręgu administracyjnym Zichenau (Ciechanów)
Authors: Pulvermacher Alexandra
Published: October 2024

Na ziemiach okupowanej Polski Niemcy stosowali tzw. areszt prewencyjny (Schutzhaft), który miał służyć unieszkodliwieniu potencjalnego ruchu oporu. Do czerwca 1941 roku aresztowano około 44 000 polskich obywateli. Szczególnie chętnie okupanci sięgali po ten środek zapobiegawczy wobec członków polskiej inteligencji. Ponad połowa aresztowanych nie dotrwała do końca wojny z powodu nieludzkich warunków panujących w miejscach przetrzymywania.
Influence of dysbiotic syndrome on the formation of experimental nepropathy
Authors: Stepan V. , Sydorchuk R. , Stepan N.
Published: October 2024

Kidneys are sensitive to damage by pathogenic factors of dysbiotic syndrome, among which lipopolysaccharide is the main one. However, the influence of the dysbiotic syndrome on the formation of nephropathy has not been studied enough.
The aim of the study is to determine the effect on the kidneys of rats of an experimental dysbiotic syndrome, which was modeled using the antibiotic lincomycin in combination with the administration of epinephrine.
Material and methods. Experimental dysbiotic syndrome (systemic dysbiosis) was reproduced in 21 Wistar rats (female, 11 months old, average weight 310±25 g) by administration of lincomycin with adrenaline hydrotartrate. The activity of urease and lysozyme was determined in blood serum and tissue homogenates and the degree of dysbiosis was calculated. The condition of the kidneys was assessed by the activity of elastase, urease, lysozyme, catalase, the content of malondialdehyde (MDA), creatinine, indicators of antioxidant protection.
Results. The level of urease increases in the liver of rats with experimental dysbiosis by 2.3 times, in the mucous membrane of the stomach - by two times, and in blood serum - by 2.3 times. The activity of lysozyme decreases in rats with dysbiosis: in the liver - by 42%, in the stomach - by 36%, and in blood serum - by 32%. Urease activity in the kidneys increases by 76%, lysozyme activity decreases by 33%, which indicates a 2.6-fold increase in the degree of dysbiosis. As a result of dysbiosis in the kidneys, the level of biochemical markers of inflammation significantly increases: elastase by 79.5% and MDA by 18%, catalase activity significantly decreases (by 6%).
Conclusions. The combined administration of lincomycin and adrenaline causes the development of a dysbiotic syndrome in experimental animals. Under the condition of modeling the dysbiotic syndrome, an inflammatory-dystrophic process develops in the kidneys, and the level of antioxidant protection significantly decreases. Under conditions of experimental dysbiosis, pathological processes in the kidneys are manifested to a lesser extent than in other organs, possibly due to the high initial level of lysozyme in the tissue.
Theory-Based Entrepreneurial Search
Authors: Chavda Ankur , Gans Joshua S. , Stern Scott
Published: October 2024

How should Theory-based entrepreneurs search for strategies to implement their ideas? The theory-based view of strategy posits that decision makers hold key conjectures about their path to success and use theory to understand and test beliefs underlying those conjectures. This causal framework also has implications for entrepreneurial search: the process by which entrepreneurs uncover strategies to implement their ideas. In this paper, we develop a Bayesian model where entrepreneurs update their beliefs as they conduct entrepreneurial search. We find several optimal behaviors for Theory-based entrepreneurs such as reverting to a previous strategy after finding a relatively poor strategy and continuing to search after finding a relatively good strategy, which are missing when entrepreneurs lack such a theory-based approach. As our theoretical predictions align with examples of successful entrepreneurs, our findings both provide a method to empirically identify Theory-based entrepreneurs and demonstrate the usefulness of applying the theory-based view to entrepreneurial behavior more generally.
the philosophy of liberation for/with children: in search of liberation and the creation of an ageless pueblo
Authors: Padilla rosas Erick javier
Published: October 2024

From its origins, the philosophy of liberation has had both a critical and a creative aspect. The first seeks to critically examine domination, dependency, and the permanent effects of colonization. The second aims to create and re-create the liberation of peoples, developing and reconstituting ways of existing, imagining, thinking, and philosophizing that surpass colonial ways of existing, imagining, thinking, and philosophizing. Thus, for the philosophy of liberation, the liberation of peoples is distinguished from the notions of emancipation and freedom that hide reality under processes of ideologization. An example of the latter is modernity’s notion of emancipation. In this paper, I propose to approach the critical and creative function of the philosophy of liberation from a childist lens in which not only the voices of children are considered, but also the adultist and modern vision of emancipation is overcome. This will be particularly important to continue the legacy of the philosophy of liberation, and its mission to criticize and create from the political and philosophical participation of the victims in the processes of ideologization. From this legacy the children are participants, who, by engaging in pedagogical practices of liberation, act as un pueblo, a collective political actor without age. of the latter is modernity’s notion of emancipation. In this paper, I propose to approach the critical and creative function of the philosophy of liberation from a childist lens in which not only the voices of children are considered, but also the adultist and modern vision of emancipation is overcome. This will be particularly important to continue the legacy of the philosophy of liberation, and its mission to criticize and create from the political and philosophical participation of the victims of the processes of ideologization. Of this legacy, the children are participants, who, by engaging in pedagogical practices of liberation, act as un pueblo, a collective political actor without age.
Recursos Educacionais Abertos: uma revisão sistemática dos artigos no portal da Capes com um olhar especial para o Ensino de Ciências
Authors: Araujo da Silva Amanda , VIEIRA DE CARVALHO ROCHA MOLISANI DANIELA , Delgado Machado Maria Auxiliadora
Published: October 2024

Neste trabalho buscamos analisar de forma sistemática as publicações sobre Recursos Educacionais Abertos (REA) presentes na Plataforma Periódicos CAPES, a fim de conhecermos as principais perspectivas de uso e/ou produção desses recursos na Educação de forma geral e mais especificamente no Ensino de Ciências. A seleção dos artigos de interesse se deu pela menção do termo REA nos títulos ou nos resumos. A partir desses elementos textuais procedemos à análise das ocorrências de palavras nos títulos e, a partir da análise categorial temática, os sentidos com que essas palavras estavam associadas aos REA. Usamos nessa análise o software Voyant Tools, disponível de forma gratuita na rede de internet. Nossos resultados mostram que o nível de produção de REA ainda é bem menor que os levantamentos bibliográficos realizados em torno do tema. Em sua maioria, os REA produzidos pertencem à área da saúde, em especial à enfermagem, e ao ensino de história. Somente três artigos entre os 95 selecionados se relacionavam ao Ensino de Ciências e desses somente três tratavam da produção de algum recurso. Esse cenário permite inferir que os REA ainda não foram identificados pelos profissionais do Ensino de Ciências como uma possibilidade potencializadora de conteúdos, principalmente numa situação de ausência de laboratórios que caracteriza muitas escolas da Educação Básica. Motivados por essa ausência de recursos, apresentamos a produção de um REA, desenvolvido por uma das autoras, e que servirá como um piloto para as futuras etapas do projeto, que preveem a produção de REA específicos para o Ensino de Ciências.
Questão ambiental e dinâmica expansiva do capital: renda fundiária e a determinação social das condições naturais
Authors: Monerat Julio Cesar Pereira
Published: October 2024

O artigo relaciona a dinâmica necessariamente expansiva do capital – enquanto valor que se valoriza – e a renda fundiária – enquanto punção do valor social. Essa relação revela-se fundamental para a compreensão crítica das consequências ambientais da dinâmica expansiva do capital sobre parcelas crescentes da natureza. Recorre à categoria marxiana de renda fundiária – I, II e absoluta –, desdobrando-a na análise de situações concretas de expansão capitalista no campo/ambiente que se efetivam em uma historicidade não linear, mas fundamentalmente desigual e combinada. São discutidos temas relacionados ao monopólio da terra, ao papel regulador do pior solo, às vantagens e obstáculos postos ao capital agrário, dentre outros que permitem identificar a determinação social da relação capital-natureza. O artigo salienta o papel do capital no aproveitamento das vantagens, na geração de obstáculos e, principalmente, nas formas de superação das situações de crise ambiental, o que se dá pela ecologização capitalista e crescente mercadorização da natureza.
A dimensão socioeducativa do serviço social em Angola sob a perspectiva de Gramsci
Authors: Dias Mateus José , Chedian Pimentel Rosalinda
Published: October 2024

Este artigo objetiva analisar a dimensão socioeducativa do Serviço Social sob uma perspectiva Gramsciana, pautada no materialismo histórico-dialético, com base em pesquisa bibliográfica. Foram levantados livros e artigos de pesquisadores angolanos (assistentes sociais) e outros autores brasileiros, cujas abordagens nos levaram a concluir (provisoriamente) que Antônio Gramsci é uma figura importante na América Latina e, de certa forma, por isso, o Serviço Social nesta região tem uma particularidade que dimensiona significativamente a emancipação política da profissão. Em Angola a realidade é diferente, ou seja, não se tem aquele pensador marxista como referência. O Serviço Social em Angola em sua dimensão socioeducativa não apresenta um diálogo direto com o pensamento de Gramsci. Ao contrário, possui uma visão da profissão como “ajuda”, fundamentada na “Pedagogia da Ajuda”, portanto, calcada no humanismo cristão abstrato, que dialoga com a teoria social positivista de matriz funcionalista. A forma como se processa o capitalismo dependente em Angola dificulta as possibilidades de emancipação política da classe trabalhadora, ao ponto de que algumas profissões, como o Serviço Social, não se reconhecem como trabalho. Deste modo, as concepções dos profissionais dessa área têm poucas recorrências à teoria social emancipatória. Mas com a presença do marxismo na profissão desde 2016, há possibilidades de se construir gradativamente a interlocução dos assistentes sociais com o pensamento de Antônio Gramsci.
Palavras chaves: Angola; dimensão socioeducativa; Serviço Social; Gramsci.
Voltar ao Centro
Authors: Olina Dourado Elziane , Rabelo Rangel Júlia
Published: October 2024

Por motivos técnicos, o arquivo da Mostra Fotográfica precisou ser dividido em duas partes:
     - o primeiro PDF vai da página 269 a página 280 e constam o texto de abertura da Mostra + as 12 primeiras fotos;
     - o segundo PDF vai da página 281 a página 287 e dá continuidade às demais fotos, da 13 a 21.
Limites absolutos do capital na crise estrutural: uma análise em Mészáros
Authors: Da Silva Santos Milena
Published: October 2024

O texto tem como objetivo analisar os limites absolutos do capital no processo de crise estrutural, a partir das formulações teóricas de István Mészáros. A investigação utilizou o enfoque materialista-histórico e dialético, de base marxiana, e teve como procedimento metodológico a pesquisa bibliográfica. Analisa as determinações fundamentais da crise estrutural e evidencia a ativação dos limites absolutos do sistema do capital. Para a permanência do movimento de autorreprodução ampliada do capital, o sistema demanda o total controle da base material e um comando político que se apresenta através do Estado. As ações corretivas do capital (na economia e na política) contribuem para a manutenção do sistema de deslocamento de contradições. Porém, este mecanismo não se torna eficiente diante da crise estrutural e dos limites absolutos. Ressaltamos que a constituição da relação capital impede a resolução desses problemas e que estes só podem ser eliminados com a superação do capital.
Questão social e pandemia da Covid-19: expressões sobre a educação pública brasileira
Authors: Da Silva Souza Lilian Angélica , Rodrigues Freire Montavoni Pereira Amabele , Guimarães Oliveira Luiza
Published: October 2024

O presente artigo tem como objetivo analisar as expressões da questão social durante a pandemia da Covid-19 sobre a educação pública no Brasil. Baseada no método materialista histórico-dialético, a pesquisa tem caráter quanti-qualitativo, é classificada como exploratória e, no seu percurso metodológico, utiliza-se da revisão bibliográfica. Foram analisados, entre os anos de 2020 e 2022, em anais de eventos e em determinadas revistas com publicações na área de Serviço Social, trabalhos e artigos que tratavam das relações entre pandemia e educação pública brasileira. Os resultados apontaram 27 produções, que correspondiam aos critérios de inclusão e de exclusão definidos na pesquisa. Conclui-se que assimetrias sociais, que não eram novas, como o racismo, o desemprego e a fome, refletiram em desigualdades socioeducacionais, que foram exponenciadas durante a pandemia, como parte das crises estruturais do capital.
A percepção dos profissionais dos CRAS sobre o atendimento às demandas de violação de direitos
Authors: Zanin Daiane , Von Hohendorff Jean
Published: October 2024

O objetivo deste artigo é abordar a percepção dos/as profissionais que atuam em centros de referência de assistência social (Cras) sobre o atendimento da política de assistência social às demandas de violação de direitos em municípios que não possuem em sua área de abrangência o Centro de Referência Especializado em Assistência Social (Creas) ou equipe técnica específica. Para tanto, foi realizada uma pesquisa qualitativa, com base em pesquisa bibliográfica, aplicação de questionário e entrevista semiestruturada. Os principais resultados demostram que a responsabilidade em atender aos dois níveis de proteção do Sistema Único de Assistência Social (Suas) – proteção social básica (PSB) e proteção social especial (PSE) – implica prejuízos à prevenção e ao atendimento das demandas de violação de direitos, comprometendo o exercício das funções da política de assistência social, bem como repercute no trabalho dos/as profissionais pela intensificação e sobrecarga de trabalho.
Using Augmented Reality to Teach Digital Literacy Course to Primary School Children with Special Educational Needs
Authors: Rakhimzhanova Lyazzat , Issabayeva Darazha , Kultan Jaroslav , Baimuldina Nazira , Issabayeva Zhanylsyn , Aituganova Zhamila
Published: October 2024

Augmented reality technologies can create unique interactive learning environments for students with special educational needs that enrich the learning process and provide immediate feedback. This research analyzed the use of augmented reality in teaching digital literacy courses for primary school children with special educational needs. The study involved a quasi-experiment with participants using a mobile augmented reality application to assess its impacts on learning outcomes. The results showed the positive effects of augmented reality on student achievement. The results highlight the potential of augmented reality in inclusive education. In addition, the findings emphasize the importance of further research and development in this area and an increased use of augmented reality to improve the educational experience of students with disabilities. In light of the results, we conclude with recommendations for integrating augmented reality into educational programs and improving educational practices.
Confirmed record of Criorhina vivida Brunetti, 1923 (Diptera, Syrphidae) in India with description of the male, and notes on the distribution and checklist of the genus in the country
Authors: MAQBOOL AMIR , YATOO SUHAIB FIRDOUS , AKBAR SHAHID ALI , BANU A. NAJITHA , WACHKOO AIJAZ AHMAD
Published: October 2024

Based solely on the holotype, different information sources indicate the possible presence of Criorhina vivida Brunetti, 1923 in India and Pakistan. However, none of them confirm this scenario. In this study, we confirm the occurrence of the species in India, and provide first description of the male. Additionally, we provide information on distribution, a species checklist and identification key of the genus in the country.
Update on the aetiopathogenesis of obstructive sleep apnea: Role of inflammatory and immune mediated mechanisms
Authors: Nag Deb Sanjay , Varghese Koshy , Swain Amlan , Patel Roushan , Sahu Seelora , Sam Merina
Published: October 2024

Obstructive sleep apnea (OSA) is often a lifestyle disease associated with obesity, which is rapidly evolving as a major health concern with diverse multisystemic implications. To prevent and mitigate its adverse effects and reduce its burden on society, its aetiopathogeneses must be precisely understood. Numerous studies focusing on the range of diverse anatomic, functional, and lifestyle factors have already been carried out to determine the possible contributory roles of these factors in OSA. Recently, evidence to validate the role of inflammatory pathways and immune mechanisms in the aetiopathogeneses of OSA is being developed. This allows for further research and translation of such knowledge for targeted therapeutic and preventive interventions in patients with or who are at risk of developing OSA.
Characterizations of complex P-matrices
Authors: Tsatsomeros Michael , Olesky Dale , Van den Driessche Pauline
Published: October 2024

A P-matrix is a square matrix all of whose principal minors are positive. The characterization of real P-matrices as matrices that do not reverse the sign of any nonzero real vector is generalized to complex P-matrices by associating them with the reflection of complex vectors. This prompts the extension of other P-matrix properties and related real matrix classes to the complex field. In particular, semipositivity of real P-matrices is generalized to complex P-matrices. Principal pivot transforms and Cayley transforms of complex P-matrices are also considered.
Five- and ten-year follow-up of medial unicompartmental knee arthroplasties in obese and non-obese patients
Authors: Gregor Reinhold H. , Hooper Gary J. , Frampton Christopher
Published: October 2024

Aims

The aim of this study was to determine whether obesity had a detrimental effect on the long-term performance and survival of medial unicompartmental knee arthroplasties (UKAs).

Methods

This study reviewed prospectively collected functional outcome scores and revision rates of all medial UKA patients with recorded BMI performed in Christchurch, New Zealand, from January 2011 to September 2021. Patient-reported outcome measures (PROMs) were the primary outcome of this study, with all-cause revision rate analyzed as a secondary outcome. PROMs were taken preoperatively, at six months, one year, five years, and ten years postoperatively. There were 873 patients who had functional scores recorded at five years and 164 patients had scores recorded at ten years. Further sub-group analysis was performed based on the patient’s BMI. Revision data were available through the New Zealand Joint Registry for 2,323 UKAs performed during this time period.

Results

Obese patients (BMI > 30 kg/m2) were 3.1 years younger than non-obese patients (BMI < 30 kg/m2) at the time of surgery (mean age of obese patients 65.5 years (SD 9.7) and mean age of non-obese patients 68.6 years (SD 10.1)). Preoperatively, obese patients tended to have significantly lower functional scores than non-obese patients, which continued at five and ten years postoperatively. At these timepoints, obese patients had significantly lower scores for most PROMs measured compared to non-obese patients. However, there was no significant difference in the improvement of any of these scores after surgery between obese and non-obese patients. There was no significant difference in revision rates between obese and non-obese patients at any time. All-cause revision rate for obese patients was 0.73 per 100 observed component years compared to 0.67 in non-obese patients at ten years. There was also no significant difference in the aseptic loosening rate between groups.

Conclusion

Our study supports the use of UKAs in obese patients, with similar benefit and survival compared to non-obese patients at ten years.
An Accelerated Ray Tracing Method based on Embree3 Ray Tracing Library for Targets with Non-uniform Thickness Materials
Authors: Zhu Yi , Wei Gao , Li Jianzhou
Published: October 2024

This paper proposes an accelerated ray tracing method utilizing the Embree3 ray tracing library for targets with non-uniform thickness materials. In contrast to the traditional surface-based ray tracing, the proposed approach performs ray tracing within the materials, since surface tracing is ineffective for materials with non-uniform thickness. To ensure efficiency and handle the overlapping grids between different materials, the Embree3 ray tracing library is introduced to ray intersection. Numerical results confirm that the proposed method surpasses existing methods in terms of efficiency and applicability while maintaining accuracy.
Comparative Study of High-speed Permanent Magnet Synchronous Motors with In-line Slot Conductors and Equidirectional Toroidal Windings
Authors: Sun Yinjun , Wang Peixin , Nie Rui , Nie Fuquan , Gao Peng , Si Jikai
Published: October 2024

The high-speed permanent magnet synchronous motor (HSPMSM) plays an important role in a wide range of engineering fields due to its high power density, high efficiency, and light weight. In this paper, a HSPMSM equipped with in-line slot conductors(I-LSC) is proposed and compared with one equipped with equidirectional toroidal winding (ETW). Firstly, the differences between them are revealed, including topology, back-electromotive force (EMF), slot fill factor, copper loss, and torque. Secondly, two-dimensional finite element method (2D-FEM) tools are used to obtain more precise performance such as air-gap field, back-EMF, torque characteristics, efficiency maps, and the unbalanced magnetic force (UMF). Considering the end-windings of copper loss of ETW and the end ring copper loss of I-LSC, the losses and efficiency of two motors are simulated by three-dimensional finite element method (3D-FEM). Finally, the simulation results validate the feasibility of the newly proposed winding and indicate that in-line slot conductors have superiority in power density due to the high slot fill factor.
Herbal Based Traditional Practices Used by the Bhotias and Gangwals of the Central Himalayan Region, Uttarakhand, India
Authors: P.S. Mehta  , K.S. Negi  , S.N. Ojha  , Anupam Rayal  , S.K. Verma
Published: October 2024

Indigenous Traditional Knowledge (ITK) on herbal medicines is gaining importance continuously, due to their efficiency, rare chances of side effects in the treatment, good faith of society on herbal medicines and their products. The present study was carried out on the tribal communities i.e., the Bhotias and Gangwals. A non-participant observation method was used to extract the knowledge from local medicine men. Ethno-medicinal uses of local plants by the natives the Bhotias and Gangwal tribes were documented.In this paper a total of 78 plants belonging to 39 families and 61 genera were recorded, which were used for the treatment of 68 diseases. Out of 78 plants, roots and rhizomes of 26 are used for medicine preparation followed by leaves (20), fruits (03), whole plant/ aerial parts (10/04), seeds (07), bark (07), flowers (07), stem (01), aerial bulbs (01), latex (02), resin (01). About 07 species were commonly used for treating wounds/ sores followed by 05 species for treating fever and 05 species for headache, 04 species each for pregnancy problems, sprains, urine problem and cold and cough. Twenty one species were found using for curing more than one ailments while 57 species were reported for single therapeutic application. Twelve species are also used as dyes, spices, condiments, flavouring agent and food items and play a significant role is rural economy of the region. P.S. Mehta E-mail: mehta.puran@yahoo.com Now, due to change of socio-economy and culture, the traditional knowledge of these communities is also diminishing. It needs to be preserved before the onslaught of modernization. There is also an urgent needof conservation and resource augmentation of these medicinal plants in their natural habitat as well as their plantation in suitable agro-climatic conditions. Thus, it was concluded that the tribes Bhotias and Gangwals possess a good knowledge of herbal based medicinal practice.
Synthesis of Multi-walled Carbon Nanotubes from Glycine Max Oil and Their Potential Applications
Authors: V.S. Angulakshmi  , C. Sathiskumar  , S. Karthikeyan
Published: October 2024

The discovery of carbon nanotubes has created new era in the field of nanotechnology. Spectacular properties of these nanostructured materials, stimulating scientists to peep into this tiny tube with ever increasing curiosity. The immediate challenge is to produce desired structural and characteristic featured carbon nanotubes in large quantities. Chemical vapor deposition is the most popular method of producing carbon nanotubes and it is of low-cost and highly useful technique for mass production of carbon nanotubes. These efforts requires not only chosen technique but also based on the precursor and the catalytic support. Glycine max oil a botanical hydrocarbon, has been found to be effective precursor for the synthesis of multi-walled carbon nanotubes (MWNTs) by Spray Pyrolysis over well dispersed Fe /Mo catalyst supported on silica at 650 °C under Ar atmosphere. As-grown MWNTs were characterized by SEM, HRTEM, Raman spectroscopy and Nitrogen adsorption studies. Raman spectroscopy revels that MWNTs are well graphitized. Dynamic and equilibrium studies of adsorption of Basic brown-4 on MWNTs were also reported.