bluuebunny/crossref_metadata_2025 huggingface dataset:
Ecological and Health Risks Attributed to Rare Earth Elements in Coal Fly Ash
Authors: Slavković-Beškoski Latinka , Ignjatović Ljubiša , Ćujić Mirjana , Vesković Jelena , Trivunac Katarina , Stojaković Jelena , Perić-Grujić Aleksandra , Onjia Antonije
Published: January 2024

The occurrence and distribution of yttrium and rare earth elements (REYs), along with major elements and heavy metal(loid)s (HMs) in coal fly ash (CFA) from five coal-fired power plants (CFPPs), were analyzed, and the REY-associated ecological and health risks were assessed. The individual REYs in CFA were abundant in the following order: Ce > La > Nd > Y > Pr > Gd > Sm > Dy > Er > Yb > Eu > Ho > Tb > Tm > Lu. The total REY content ranged from 135 to 362 mg/kg, averaging 302 mg/kg. The mean light-to-heavy REY ratio was 4.1, indicating prevalent light REY enrichment in CFA. Significantly positive correlations between the REYs suggested that they coexist and share similar origins in CFA. REYs were estimated to pose low to moderate ecological risks, with risk index (RI) values ranging from 66 to 245. The hazard index (HI) and target cancer risk (TCR) of REYs from CFA, estimated to be higher for children (HIc = 0.15, TCRc = 8.4 × 10−16) than for adults (HIa = 0.017, TCRa = 3.6 × 10−16), were well below the safety limits (HI = 1, TCR = 1.0 × 10−6). However, the danger to human health posed by HMs in the same CFA samples (HIc = 5.74, TCRc = 2.6 × 10−4, TCRa = 1.1 × 10−4) exceeded the safe thresholds (excl. HIa = 0.63). The mean RI and HI attributed to REYs in CFA were 14% and 2.6%, respectively, of the total risks that include HMs.
Resourcization of Argillaceous Limestone with Mn3O4 Modification for Efficient Adsorption of Lead, Copper, and Nickel
Authors: Li Deyun , Li Yongtao , He Shuran , Hu Tian , Li Hanhao , Wang Jinjin , Zhang Zhen , Zhang Yulong
Published: January 2024

Argillaceous limestone (AL) is comprised of carbonate minerals and clay minerals and is widely distributed throughout the Earth’s crust. However, owing to its low surface area and poorly active sites, AL has been largely neglected. Herein, manganic manganous oxide (Mn3O4) was used to modify AL by an in-situ deposition strategy through manganese chloride and alkali stepwise treatment to improve the surface area of AL and enable its utilization as an efficient adsorbent for heavy metals removal. The surface area and cation exchange capacity (CEC) were enhanced from 3.49 to 24.5 m2/g and 5.87 to 31.5 cmoL(+)/kg with modification, respectively. The maximum adsorption capacities of lead (Pb2+), copper (Cu2+), and nickel (Ni2+) ions on Mn3O4-modified argillaceous limestone (Mn3O4–AL) in mono-metal systems were 148.73, 41.30, and 60.87 mg/g, respectively. In addition, the adsorption selectivity in multi-metal systems was Pb2+ > Cu2+ > Ni2+ in order. The adsorption process conforms to the pseudo-second-order model. In the multi-metal system, the adsorption reaches equilibrium at about 360 min. The adsorption mechanisms may involve ion exchange, precipitation, electrostatic interaction, and complexation by hydroxyl groups. These results demonstrate that Mn3O4 modification realized argillaceous limestone resourcization as an ideal adsorbent. Mn3O4-modified argillaceous limestone was promising for heavy metal-polluted water and soil treatment.
Ritonavir Has Reproductive Toxicity Depending on Disrupting PI3K/PDK1/AKT Signaling Pathway
Authors: Jung Eun-Ju , Jo Jae-Hwan , Uwamahoro Claudine , Jang Seung-Ik , Lee Woo-Jin , Hwang Ju-Mi , Bae Jeong-Won , Kwon Woo-Sung
Published: January 2024

Ritonavir (RTV) is an antiviral and a component of COVID-19 treatments. Moreover, RTV demonstrates anti-cancer effects by suppressing AKT. However, RTV has cytotoxicity and suppresses sperm functions by altering AKT activity. Although abnormal AKT activity is known for causing detrimental effects on sperm functions, how RTV alters AKT signaling in spermatozoa remains unknown. Therefore, this study aimed to investigate reproductive toxicity of RTV in spermatozoa through phosphoinositide 3-kinase/phosphoinositide-dependent protein kinase-1/protein kinase B (PI3K/PDK1/AKT) signaling. Duroc spermatozoa were treated with various concentrations of RTV, and capacitation was induced. Sperm functions (sperm motility, motion kinematics, capacitation status, and cell viability) and expression levels of tyrosine-phosphorylated proteins and PI3K/PDK1/AKT pathway-related proteins were evaluated. In the results, RTV significantly suppressed sperm motility, motion kinematics, capacitation, acrosome reactions, and cell viability. Additionally, RTV significantly increased levels of phospho-tyrosine proteins and PI3K/PDK1/AKT pathway-related proteins except for AKT and PI3K. The expression level of AKT was not significantly altered and that of PI3K was significantly decreased. These results suggest RTV may suppress sperm functions by induced alterations of PI3K/PDK1/AKT pathway through abnormally increased tyrosine phosphorylation. Therefore, we suggest people who use or prescribe RTV need to consider its male reproductive toxicity.
Zambia: A Narrative Review of Success and Challenges in Lymphatic Filariasis Elimination
Authors: Chimfwembe Kingford , Shirley Hugh , Baker Natalie , Wamai Richard
Published: January 2024

The establishment of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) to stop the transmission of infection has significantly reduced the incidence of lymphatic filariasis, a debilitating mosquito-borne neglected tropical disease. The primary strategies that have been employed include mass drug administration (MDA) of anthelminthics and morbidity management and disability prevention (MMDP). While some countries have been able to reach elimination status in Africa, there is still active transmission of LF in Zambia. The nematode responsible for the disease is Wuchereria bancrofti, which is transmitted by Anopheles mosquitoes. To alleviate the suffering of those infected by the disease, the Zambian Ministry of Health launched a program to eliminate LF as a public health problem in 2003. This project reviewed the efforts to achieve the elimination of LF in Zambia, past and present government policies, and the anticipated challenges. MDAs have been conducted since 2014 and coverage has been between 87% and 92%. Zambia has now moved towards pre-transmission assessment surveys (PRETAS) and transmission assessment surveys (TAS). MMDP is a major priority and planned to be conducted between 2022 and 2026. COVID-19 presented a new challenge in the control of LF, while climate change, immigration, co-infections, and funding limitations will complicate further progress.
A GIS-Based Emotion Detection Framework for Multi-Risk Analysis in Urban Settlements
Authors: Cardone Barbara , Di Martino Ferdinando , Miraglia Vittorio
Published: January 2024

The application of sentiment analysis approaches to information flows extracted from the social networks connected to particular critical periods generated by pandemic, climatic and extreme environmental phenomena allow the decision maker to detect the emotional states of citizens and to determine which areas are most at risk and require specific resilient adaptation interventions. Of particular relevance today is the need to analyze the multiple risks generated by extreme phenomena in urban settlements in order for the decision maker to identify which areas are most at risk and prepare resilient intervention plans with respect to all the phenomena analyzed. In recent years, the COVID 19 pandemic emergency has forced citizens to undergo specific restrictions to protect their health; to these were added critical issues due to the occurrence of extreme climatic or environmental phenomena. In order to monitor pandemic and climate/environmental multi-risks in urban settlements, we propose a GIS-based framework in which an emotion detection method is applied to determine the prevailing emotional categories in urban study areas during pandemic periods and in the presence of extreme climatic phenomena. The framework was tested on a study area based in the six districts of the city of Bologna (Italy) in order to detect, based on the emotions expressed on social channels, which were the most critical city neighborhoods in pandemic periods and in the presence of extreme heat wave climatic events. The results show that the proposed model can represent a valid tool to support decision makers in identifying the most critical urban areas in the presence of pandemic and climate/environmental multi-risks.
Prevalence of Hepatitis B in Canadian First-Time Blood Donors: Association with Social Determinants of Health
Authors: O’Brien Sheila F. , Ehsani-Moghaddam Behrouz , Goldman Mindy , Drews Steven J.
Published: January 2024

Hepatitis B is transmitted sexually, by blood contact, and vertically from mother to child. Chronic hepatitis B is often seen in immigrants from higher-prevalence countries and their Canadian-born children. We assessed the relationship between hepatitis B and social determinants of health. Included were 1,539,869 first-time Canadian blood donors from April 2005 to December 2022. All donations were tested for hepatitis B markers. Logistic regression was fit with chronic hepatitis B as the dependent variable and age, sex, year, and ethnocultural composition and material deprivation quintiles as independent variables. Chronic hepatitis B prevalence was 47.5/100,000 (95% CI 41.5–53.5, years 2017–2022). Chronic hepatitis B prevalence was elevated in males, older age groups, and those living in more materially deprived and higher ethnocultural neighbourhoods. Of 212,518 donors from 2020 to 2022 with race/ethnicity data, chronic hepatitis B prevalence was highest in East Asians. The findings are consistent with infections in immigrants, acquired in their country of origin, in their Canadian-born children and in those with other risks. As blood donors are a low-risk population unaware of their infection and unlikely to seek testing, our results highlight the ongoing public health challenges of diagnosing chronic hepatitis B and treating it when appropriate.
Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy
Authors: Li Feng , Yu Hao , Qi Aosi , Zhang Tianyi , Huo Yuran , Tu Qiuse , Qi Chunyun , Wu Heyong , Wang Xi , Zhou Jian , Hu Lanxin , Ouyang Hongsheng , Pang Daxin , Xie Zicong
Published: January 2024

Pigs play important roles in agriculture and bio-medicine; however, porcine viral infections have caused huge losses to the pig industry and severely affected the animal welfare and social public safety. During viral infections, many non-coding RNAs are induced or repressed by viruses and regulate viral infection. Many viruses have, therefore, developed a number of mechanisms that use ncRNAs to evade the host immune system. Understanding how ncRNAs regulate host immunity during porcine viral infections is critical for the development of antiviral therapies. In this review, we provide a summary of the classification, production and function of ncRNAs involved in regulating porcine viral infections. Additionally, we outline pathways and modes of action by which ncRNAs regulate viral infections and highlight the therapeutic potential of artificial microRNA. Our hope is that this information will aid in the development of antiviral therapies based on ncRNAs for the pig industry.
mRNA Vaccine Nanoplatforms and Innate Immunity
Authors: Wei Lai , Dong Chunhong , Zhu Wandi , Wang Bao-Zhong
Published: January 2024

mRNA-based vaccine technology has been significantly developed and enhanced, particularly highlighted by the authorization of mRNA vaccines for addressing the COVID-19 pandemic. Various biomaterials are developed in nano-scales and applied as mRNA vaccine delivery platforms. However, how these mRNA nanoplatforms influence immune responses has not been thoroughly studied. Hence, we have reviewed the current understanding of various mRNA vaccine platforms. We discussed the possible pathways through which these platforms moderate the host’s innate immunity and contribute to the development of adaptive immunity. We shed light on their development in reducing biotoxicity and enhancing antigen delivery efficiency. Beyond the built-in adjuvanticity of mRNA vaccines, we propose that supplementary adjuvants may be required to fine-tune and precisely control innate immunity and subsequent adaptive immune responses.
Burden and Impact of Reactogenicity among Adults Receiving COVID-19 Vaccines in the United States and Canada: Results from a Prospective Observational Study
Authors: Rousculp Matthew D. , Hollis Kelly , Ziemiecki Ryan , Odom Dawn , Marchese Anthony M. , Montazeri Mitra , Odak Shardul , Jackson Laurin , Miller Angela , Toback Seth
Published: January 2024

As SARS-CoV-2 variants continue to emerge, vaccination remains a critical tool to reduce the COVID-19 burden. Vaccine reactogenicity and the impact on work productivity/daily activities are recognized as contributing factors to vaccine hesitancy. To encourage continued COVID-19 vaccination, a more complete understanding of the differences in reactogenicity and impairment due to vaccine-related side effects across currently available vaccines is necessary. The 2019nCoV-406 study (n = 1367) was a prospective observational study of reactogenicity and associated impairments in adults in the United States and Canada who received an approved/authorized COVID-19 vaccine. Compared with recipients of mRNA COVID-19 booster vaccines, a smaller percentage of NVX-CoV2373 booster recipients reported local and systemic reactogenicity. This study’s primary endpoint (percentage of participants with ≥50% overall work impairment on ≥1 of the 6 days post-vaccination period) did not show significant differences. However, the data suggest that NVX-CoV2373 booster recipients trended toward being less impaired overall than recipients of an mRNA booster; further research is needed to confirm this observed trend. The results of this real-world study suggest that NVX-CoV2373 may be a beneficial vaccine option with limited impact on non-work activities, in part due to the few reactogenicity events after vaccination.
Analysis of CVC1302-Mediated Enhancement of Monocyte Recruitment in Inducing Immune Responses
Authors: Lu Haiyan , Yu Xiaoming , Hou Liting , Zhang Yuanpeng , Li Lan , Qiao Xuwen , Cheng Haiwei , Du Luping , Chen Jin , Zheng Qisheng , Hou Jibo
Published: January 2024

Monocytes (Mos) are believed to play important roles during the generation of immune response. In our previous study, CVC1302, a complex of PRRs agonists, was demonstrated to recruit Mo into lymph nodes (LNs) in order to present antigen and secret chemokines (CXCL9 and CXCL10), which attracted antigen-specific CD4+ T cells. As it is known that Mos in mice are divided into two main Mo subsets (Ly6C+ Mo and Ly6C− Mo), we aimed to clarify the CVC1302-recruiting Mo subset and functions in the establishment of immunity. In this study, we found that CVC1302 attracted both Ly6C+ Mo and Ly6C− Mo into draining LNs, which infiltrated from different origins, injection muscles and high endothelial venule (HEV), respectively. We also found that the numbers of OVA+ Ly6C+ Mo in the draining LNs were significantly higher compared with OVA+ Ly6C− Mo. However, the levels of CXCL9 and CXCL10 produced by Ly6C− Mo were significantly higher than Ly6C+ Mo, which plays important roles in attracting antigen-specific CD4+ T cells. Under the analysis of their functions in initiating immune responses, we found that the ability of the Ly6C+ monocyte was mainly capturing and presenting antigens, otherwise; the ability of the Ly6C− monocyte was mainly secreting CXCL9 and CXCL10, which attracted antigen-specific CD4+ T cells through CXCR3. These results will provide new insights into the development of new immunopotentiators and vaccines.
Development of Vaccines against Emerging Mosquito-Vectored Arbovirus Infections
Authors: Principi Nicola , Esposito Susanna
Published: January 2024

Among emergent climate-sensitive infectious diseases, some mosquito-vectored arbovirus infections have epidemiological, social, and economic effects. Dengue virus (DENV), West Nile virus (WNV), and Chikungunya virus (CHIKV) disease, previously common only in the tropics, currently pose a major risk to global health and are expected to expand dramatically in the near future if adequate containment measures are not implemented. The lack of safe and effective vaccines is critical as it seems likely that emerging mosquito-vectored arbovirus infections will be con-trolled only when effective and safe vaccines against each of these infections become available. This paper discusses the clinical characteristics of DENV, WNV, and CHIKV infections and the state of development of vaccines against these viruses. An ideal vaccine should be able to evoke with a single administration a prompt activation of B and T cells, adequate concentrations of protecting/neutralizing antibodies, and the creation of a strong immune memory capable of triggering an effective secondary antibody response after new infection with a wild-type and/or mutated infectious agent. Moreover, the vaccine should be well tolerated, safe, easily administrated, cost-effective, and widely available throughout the world. However, the development of vaccines against emerging mosquito-vectored arbovirus diseases is far from being satisfactory, and it seems likely that it will take many years before effective and safe vaccines for all these infections are made available worldwide.
A Potential Association between Abdominal Obesity and the Efficacy of Humoral Immunity Induced by COVID-19 and by the AZD1222, Convidecia, BNT162b2, Sputnik V, and CoronaVac Vaccines
Authors: Angeles-Martinez Javier , Monroy-Muñoz Irma Eloisa , Muñoz-Medina José Esteban , Fernandes-Matano Larissa , Salas-Lais Ángel Gustavo , Hernández-Cueto Ma De Los Ángeles , Bravo-Flores Eyerahi , León-Juárez Moisés , Santacruz-Tinoco Clara Esperanza , Montes-Herrera Daniel
Published: January 2024

Abdominal obesity is highly prevalent in Mexico and has a poor prognosis in terms of the severity of coronavirus disease (COVID-19) and low levels of antibodies induced by infection and vaccination. We evaluated the humoral immune response induced by COVID-19 and five different vaccination schedules in Mexican individuals with abdominal obesity and the effects of other variables. This prospective longitudinal cohort study included 2084 samples from 389 participants. The levels of anti-S1/S2 and anti-RBD IgG antibodies were measured at various time points after vaccination. A high prevalence of hospitalization and oxygen use was observed in individuals with abdominal obesity (AO) who had COVID-19 before vaccination; however, they also had high levels of anti-S1/S2 and anti-RBD-neutralizing IgG antibodies. The same was true for vaccination-induced antibody levels. However, their longevity was low. Interestingly, we did not observe significant differences in vaccine reactogenicity between abdominally obese and abdominally non-obese groups. Finally, individuals with a higher body mass index, older age, and previous COVID-19 had higher levels of antibodies induced by COVID-19 and vaccination. Therefore, it is important to evaluate other immunological and inflammatory factors to better understand the pathogenesis of COVID-19 in the presence of risk factors and to propose effective vaccination schedules for vulnerable populations.
The experience of treating chronic peri-implantitis in HIV positive patients
Authors: Morozov M. A. , Iordanishvili A. K. , Serikov A. A.
Published: January 2024

Relevance. There is a scarcity of data regarding the treatment of chronic peri-implantitis in HIV-positive patients. The refinement of available techniques for managing inflammation around dental implants holds significant importance, particularly in individuals infected with HIV. Hence, this study aims to consolidate clinical experiences in managing chronic peri-implantitis in HIV-positive patients.Materials and methods. The study involved six male patients (treatment group), aged 35 to 54, diagnosed with chronic peri-implantitis, exhibiting inflammation around dental implants and testing HIV positive. These patients, under dynamic observation by their infectious disease specialist, were consistently receiving antiretroviral treatment. The control group consisted of 10 males aged 28 to 55, devoid of HIV or any other condition causing secondary immunodeficiency. Oral cavity microbiota and mucosal immunity were examined, and treatment for chronic peri-implantitis was administered. Both groups had dental implants for 5 to 7 years. The specifics of the implantation systems were not explored.Results. HIV-positive patients with peri-implantitis exhibited alterations in microbiota and mucosal immunity, correlating with "viral load" indicators. The study presented combined treatment outcomes for periodontitis and the influence of adjusted antiretroviral therapy on mucosal immunity and oral cavity microbiota parameters.Conclusion. Peri-implantitis onset in HIV-positive patients with adequate oral hygiene might be linked to an underlying factor involving ineffective administration of antiretroviral treatment. Consequently, diagnosing periimplantitis in HIV-positive individuals should not only entail appropriate therapeutic and preventive measures as part of a comprehensive peri-implantitis treatment regimen, along with precise oral hygiene correction performed professionally, but also timely referral to an infectious disease specialist for adjustment of antiretroviral therapy.
RESEARCH OF THE BINDER SYSTEM STRUCTURE BASED ON THERMAL ACTIVATED EXPANDED CLAY DUST
Authors: Knyazeva S. , Yakovlev G. , Bur'yanov A. , Zhukov A. , Kirshin I.
Published: January 2024

The production of Portland cement is associated with a high consumption of mineral raw materials and significant emissions of carbon dioxide into the atmosphere. Therefore, the partial replacement of cement with technogenic mineral additive in cement compositions is a rational way of utilizing production waste. Besides, the use of industrial waste products as mineral additives allows solving environment problems and reducing the consumption of primary natural resources.

This paper presents the study on the hydraulic activity of thermally activated expanded clay dust used as an active mineral additive in cement compositions. Expanded clay dust is an industrial waste formed during the production of ceramsite gravel, and captured in the dust cleaning systems of kilns: dust chambers, cyclones, filters.

A comprehensive study of the composition, containing expanded clay dust and water, was carried out using the IR spectral analysis, differential scanning calorimetry and scanning electron microscopy with X-ray microanalysis.

It was established that the strength of baked samples increased by 80% after immersion in water. The main hydration products of baked expanded clay dust are three types of compounds - fibrous crystals of calcium hydrosulfoaluminate, calcium hydroaluminates in the form of cruciform twins, amorphized spherulite-like formations based on low-base calcium silicate hydrates.
HISTORICAL AND NATURAL ARCHITECTURAL COMPLEX PARAMONOV WAREHOUSES IN ROSTOV-ON-DON
Authors: Petrusenko Yu. , Belova A.
Published: January 2024

This paper examines the history and architecture of a unique historical and natural architectural complex of export grain warehouses of the second half of the XIX century in Rostov-on-Don. The objects under study are inextricably linked with the historical landscape, the Bogatyanovsky tract, and the urban environment. The buildings of grain warehouses stand on an ancient aquifer slope with springs and hydraulic devices for organizing their flows. The purpose of the study is a detailed examination of the object of cultural heritage of federal significance "Complex of export grain warehouses, XIX century.". In the course of the study, the architectural, artistic and design features of each of the buildings included in the complex of grain warehouses belonging to Paramonov and Maximov were formulated. The studied objects of export grain warehouses are decorated in a "brick" style. At that time, the "brick" style represented a fundamentally new compositional solution of volumes and a variety of plastic forms of brick decor, which conditioned the aesthetic perception of industrial architecture structures. The characteristic features corresponding to the "brick" style are revealed. The initial design solutions based on the preserved archival data on the object of cultural heritage were studied and project proposals for the reconstruction of warehouses with possible operation and adaptation to new functions in modern urban conditions were considered, new factual data were obtained.
PYRITE CANDICE AS A FILLER FOR COMPOSITE MATERIAL BASED ON STYRENE-BUTADIENE RUBBER
Authors: Bondarenko N. , Kovylova Yu. , Dacenko A.
Published: January 2024

Currently, recycling waste from various types of production, as well as finding the possibility of reusing it, is a very relevant topic. In the modern world, rubbers make a tremendous contribution to the development of the industrial sector. In order to study the possibility of using pyrite cinders as a filler for a rubber mixture based on styrene-butadiene rubber, the elastic-strength and rheological characteristics of the finished composite mixtures were studied, and the contact angle of wetting was determined to assess the interaction of the compositions with other materials. It was established that there was no influence of pyrite cinders on the nature of the surface of the rubber mixture. The dependence of the storage modulus on the deformation amplitude for different types of fillers has been established, which makes it possible to evaluate the qualitative and quantitative distribution of the filler in the polymer and the interaction of the polymer and the filler. It was revealed that pyrite cinders and chalk have a weak interaction with the polymer, from which it follows that they behave as a non-reinforcing filler, but their introduction into the polymer matrix does not deteriorate the elastic-strength properties of the rubber. The dependence of stress on deformation for mixtures with different types of fillers has been established. It was established that in terms of technological characteristics, no deviations in the material from the generally accepted patterns of introducing fillers into the polymer matrix were found. The values remain at the level of unfilled rubber and rubber filled with technical chalk. The general complex of properties of the composition based on styrene-butadiene rubber with pyrite cinders allows it to be recommended, after modification, for use in the production technology of rubber products.
MOBILE ROBOT MOTION CONTROL FOR DIFFERENT PATHS ON THE BASIS OF THE PRINCIPLE OF REDUCTION OF THE THEORY OF FUZZER
Authors: Lazarev M. , Ezhkova V.
Published: January 2024

The object of the study is the control of the movement of a mobile robot along a line. To build automatic control systems for robots, various algorithms are used, for example, PID controllers, as well as algorithms based on fuzzy logic methods. Methods of the fuzzy theory form one of the universal approaches to the analysis and modeling of applied problems, including in matters of robot control.

In any study, problems arise immediately as soon as events (facts) are accepted as fuzzy, for example, due to inaccurate measurement, fuzzy description, etc. The concept of fuzziness is intuitively clear to everyone, but its formalization causes difficulties, which are always of a fundamental nature. Consideration of the foundations of the theory is caused by the search for possible solutions to problems in the experimental part of the study, which addresses the issues of speed regulation and dynamic accuracy of the movement of a mobile robot.

The article puts forward a hypothesis about the effectiveness of the method of controlling the movement of a mobile robot based on the fuzzy theory in comparison with the PID controller. To substantiate the hypothesis, a description of the movement of the robot in terms of fuzzy theory is given, the features of the movement of the robot depending on the type of tracks are considered, a fragment of the program for implementing a controller based on fuzzy logic is presented, and a number of experiments are carried out.

Experimental verification showed a more stable and faster movement of the robot along the tracks and confirmed the hypothesis of the study. The results of the experiments made it possible to correct the fuzzy inference rules and the robot motion control program. The results obtained open up new possibilities for the wide application of fuzzy theory in robotics.
Aspectos clinicopatológicos do Lipoma Intraoral – relato de caso
Authors: Silva Laura Cecília Monteiro , Barbosa Sudaleif dos Santos Silva , Da Silva Luiz Arthur Barbosa
Published: January 2024

Lipomas intraorais são neoplasias mesenquimais benignas que surgem a partir da proliferação de adipócitos maduros. Podem acometer diversas regiões do corpo e em cerca de 1-5% dos casos surgem em cavidade oral. O objetivo deste trabalho é relatar o caso de uma paciente do sexo feminino, 36 anos, com queixa de “caroço” na língua com evolução de 2 anos. Ao exame intraoral, observou-se a presença de lesão nodular, bem delimitada, com coloração normal da mucosa, assintomática, localizada em região anterior esquerda de dorso da língua. Diante das características clínicas observadas, levantou-se a hipótese diagnóstica de Hiperplasia fibrosa. Foi realizada a biópsia excisional e durante fixação do espécime no formol a 10%, notou-se que o mesmo flutuou. Diante disso, foi incluída a hipótese diagnóstica de Lipoma, tendo sido confirmada esta hipótese após realização da análise histopatológica. A paciente encontra-se há 3 anos sem sinais de recidiva da lesão.
A importância da analgesia no parto vaginal
Authors: Maia Rusnaini da Silva , Costa Lucas Lima
Published: January 2024

Objetivo: Analisar a relevância da utilização de métodos de alívio da dor durante o parto vaginal. Metodologia: Trata-se de uma revisão integrativa da literatura. Adotou-se como pergunta norteadora: “Qual é a importância da analgesia no parto vaginal?” Para construção da pesquisa, a coleta e análise de dados foi realizada através do Portal da Biblioteca Virtual em Saúde e das bases de dados Medical Literature Analysis and Retrievel System Online via PubMed e Google Acadêmico através dos seguintes Descritores em Ciências da Saúde (DeCS): “Analgesia Obstétrica”, “Dor do Parto” e “Trabalho de Parto” combinados entre si pelo operador booleano AND com seus respectivos correspondentes no Mesh Terms. Resultados e Discussão: Após o cumprimento dos procedimentos metodológicos, 13 artigos disponíveis no Portal da BVS, na base de dados PubMed e no Google Acadêmico foram selecionados, os quais retratam que a analgesia peridural é considerada o padrão para o manejo da dor durante o trabalho de parto. O acesso ao manejo da dor é um direito fundamental e não deve ser retido ou negado a qualquer paciente, independentemente da idade, etnia ou nível socioeconômico. Considerações Finais: O direito é violado se uma parturiente for incapaz de participar nos métodos padrão utilizados para gerir a dor do parto. A importância da analgesia durante o trabalho de parto está relacionada ao acesso que as parturientes têm aos cuidados do pré-natal.
Compreensão dos pacientes submetidas à colonoscopia frente às orientações de enfermagem no preparo do exame
Authors: Domingos Bruna Ferreira , Bohm Lilianne , Icker Patrícia Moreira , Mendes Jânifer Souza , Fernandes Hellen Maria de Lima Graf
Published: January 2024

Introdução: A colonoscopia é um exame utilizado para investigação de doenças colorretais. Para um resultado eficaz com boa visualização do cólon, é necessário o preparo intestinal de 12 a 72 horas antes, com ingestão de líquidos claros sem resíduos e laxativos, restrição de frutas, legumes e fibras. A compreensão do indivíduo sobre as orientações relacionadas ao preparo do exame pode ser prejudicada devido à ansiedade e apreensões causadas pelo fato de ser um procedimento invasivo. Objetivo: Compreender o entendimento dos pacientes quanto às orientações de enfermagem no preparo de colonoscopia. Metodologia: Estudo descritivo de abordagem qualitativa. Os participantes foram entrevistados presencialmente, antes da realização do exame de colonoscopia em uma clínica especializada de Santa Catarina. As entrevistas foram gravadas e posteriormente transcritas. Os resultados foram organizados em planilha e analisados através da análise temática. A pesquisa obedeceu aos preceitos éticos da Resolução do Conselho Nacional de Saúde nº 510/2016, e foi iniciada após aprovação pelo Comitê de Ética e Pesquisa por meio do CAAE 57940722.0.0000.5365. Resultados: Os resultados evidenciaram que os participantes receberam orientações claras e as informações repassadas pela equipe de enfermagem foram completas e coesas. Porém, alguns sentiram dificuldade em realizar o preparo, principalmente para conciliar a rotina de trabalho com os efeitos das medicações laxativas. Conclusão: O papel da enfermagem é fundamental na orientação do indivíduo para realização de um bom preparo, reforçando o direito ao afastamento das atividades laborais para realizá-lo corretamente.
Parada cardiorrespiratória em raquianestesia – relato de caso
Authors: Siqueira Lyza Alencar , Vieira Raquel Cristina Freire de Deus
Published: January 2024

A raquianestesia é uma técnica anestésica considerada segura devido ao baixo índice de complicações. No entanto, apesar de infrequentes, alguns riscos e efeitos indesejados podem ser relacionados a essa técnica. Como exemplo, pode-se citar as repercussões no sistema cardiovascular, que pode culminar em parada cardiorrespiratória (PCR). A PCR na raquianestesia é algo incomum, tendo cerca de 0,4 a 7 casos a cada 10.000 anestesias. O objetivo deste artigo é relatar o caso de paciente que apresentou episódio de parada cardiorrespiratória após a raquianestesia em uma cirurgia ortopédica de urgência. Conclui-se que a parada cardiorrespiratória em raquianestesia é um evento multifatorial que, mesmo com a identificação precoce desses fatores, pode ser inevitável.
Physicochemical models applied to a malt healthy-friendly soft drink production
Authors: Santos Magno Fonseca , De Paula Solciaray Cardoso Soares Estefan , Da Silva Lucas Martins , Saraiva Sérgio Henriques , Maradini Filho Antonio Manoel , Teixeira Luciano José Quintão
Published: January 2024

The increasing demand for enzymatically hydrolyzed proteins, easily digestible carbohydrates, and nutritionally enriched beverages has propelled the popularity of malt-based health-friendly soft drinks (MHFSDs). Ensuring consistent quality, safety, and flavor underscores the significance of comprehending MHFSDs' physicochemical attributes. Through the application of central composite rotational design (CCRD), the impact of light and dark malt extract concentrations (LME and DME) and added sugar (AS) on these attributes was assessed. CCRD facilitated the creation of predictive mathematical models for pivotal physicochemical properties in MHFSDs, including pH, acidity, reducing sugar, total sugar, and color. These properties exert substantial influence on MHFSDs' overall quality and sensory characteristics. The reliability in understanding MHFSDs' physicochemical attributes is confirmed by high determination coefficients (pH=0.98, acidity=0.87, reducing sugar=1.00, total sugar=0.98, luminosity dimension=0.98, red-green dimension=0.76, yellow-blue dimension=0.64). The integration of CCRD and mathematical models provides a systematic, data-oriented strategy for formulating health-friendly soft drinks that fulfill desired benchmarks, presenting consumers with a more health-conscious and enjoyable beverage alternative.
Relações entre espécies florestais como indicativo de manejo e possibilidades econômicas em ambiente de várzea
Authors: Dos Santos Gideão Costa , Pinheiro Klewton Adriano Oliveira , Pimentel José Alessandro Belém
Published: January 2024

As várzeas do estuário amazônico são ambientes reconhecidos por seus solos com alto nível de saturação hídrica, pelo domínio de poucas espécies arbóreas e a presença de um elevado número de palmeiras importantes na manutenção das comunidades ribeirinhas. Objetivou-se nesse estudo evidenciar a composição florística e a fitossociologia como ferramentas para a adoção do manejo sustentado nas várzeas. Para isso, o estudo foi realizado em uma área de várzea situada na ilha Conceição, Santa Bárbara do Pará, Estado do Pará. Foram selecionadas ao acaso dois hectares, divididos em duas parcelas de um hectare cada, 100 x 100 m, onde para facilitar o levantamento florístico, cada hectare foi subdividido em faixas de 20 x 100 m. Em cada parcela amostraram-se indivíduos à 1,30 m do solo com CAP ≥ 30 cm, estimou-se a altura comercial das espécies madeireiras; a identificação botânica foi feita no herbário João Murça Pires - MPEG para algumas espécies. A análise deu-se por meio da estrutura horizontal da floresta com os parâmetros densidade, frequência, dominância e índice de valor de importância, todos relativos e ainda, número de indivíduos e área basal. Constatou-se que as espécies de maior índice de valor de importância fitossociológica foram Euterpe oleracea, Pterocarpus officinalis, Symphonia globulifera, Hevea brasiliensis, Virola surinamensis e Carapa guianensis, destas E. oleracea destaca-se como a espécie de maior importância socioeconômica. Os valores encontrados referentes ao número de indivíduos, densidade relativa e índice valor de importância, denotam que as espécies, especialmente as de importância econômica, apresentam-se viáveis ao manejo para um aumento de produção, necessitando de técnicas especiais de manejo no sentido de elevar suas volumetrias. Conclui-se que o levantamento florístico e o uso da fitossociologia, ajudam na definição de quais espécies necessitam de manejo bem como auxiliam na definição de tratamentos silviculturais e suas intensidades.
Controle social através do monitoramento de metas municipais por meio de Tecnologias de Informação e Comunicação na região metropolitana do estado de São Paulo
Authors: Crantschaninov Tamara Ilinsky , De Medeiros Anny Karine
Published: January 2024

Um dos instrumentos apresentados pela vertente gerencialista da Administração Pública está centrada na gestão de resultados. Este artigo apresenta como a contratualização de metas ou resultados pode subsidiar estratégias de controle social, a partir de seu monitoramento por meio de Tecnologias de Informação e Comunicação (TICs). A partir desta argumentação, foram estudados os 39 municípios da região metropolitana do Estado de São Paulo, a fim de verificar se os municípios da região metropolitana de São Paulo se apropriaram do estabelecimento de metas de gestão como instrumento de políticas públicas; e se é possível, através das TICs, controlar socialmente a administração pública através de suas metas estabelecidas. Com apenas 2 municípios contando com instrumentos de controle por resultados, é feita uma discussão sobre a falta de apropriação deste instrumento e também das TICs pelos municípios, e como este processo influencia negativamente o controle social.
Removal of a local antiseptic dye on two solid supports by adsorption
Authors: Guemache Abderezak
Published: January 2024

In this research, we studied the adsorption of an Eosin B (EB) dye is a local antiseptic, available in pharmacies in the form of an active preparation on the surface of activated carbon and natural clay. Activated carbon and natural clay were characterized using various physicochemical techniques to determine the crystalline structures of the two adsorbents by DRX, and the chemical bonds by FTIR analysis, and finally, to know the maximum absorbance λmax of the dye by UV-Visible analysis. The effects of various experimental parameters, such as the effect of adsorbent mass, the initial concentration of eosin B is 1.610-4 molL-1, the contact time is 24 hours, and the pH 7 ~ 9, were studied. The removal of the dye increases with the decrease of the initial concentration of Eosin B (EB) and the contact time of the solution. The percentage of Eosin B (EB) removal increases accordingly, which arrives at 80% for activated carbon and 92% for natural clay. Langmuir and Freundlich adsorption models were used for the adsorption equilibrium descriptions. The data was very well corrected with these models. Monolayer adsorption capacities were equal to 50 mgg-1 at pH 8.3 and 25°C. Adsorption measurements show that the adsorption process is very fast and physical in nature.
Restauração ecológica de mata ciliar em região ecótono do Maranhão
Authors: Angelo Dalton Henrique , Schneider Chaiane Rodrigues , Lima Julia Cerqueira , Machado Sebastião da Silva , Gomes Jaqueline Macedo , Raabe Joabel , Arce Julio Eduardo
Published: January 2024

As nascentes, rios e suas matas ciliares desempenham um papel fundamental no desenvolvimento tecnológico, alimentar e do bem-estar da sociedade, além de contribuir para a formação das bacias hidrográficas e a conservação da biodiversidade. O objetivo do presente estudo foi diagnosticar e avaliar os impactos e as metodologias de restauração ecológica em uma nascente degradada, no município de Buritirana – MA. A metodologia consistiu na avaliação dos impactos por uma tabela de interações básica da nascente, e com isso implantar um projeto de restauração ecológica com associação de distintos métodos e técnicas. Os resultados demonstraram uma área encontra-se com elevado grau de degradação, especialmente pelos impactos negativos indiretos observados. Em relação à restauração ecológica, o plantio resultou em uma baixa sobrevivência de mudas, associado ao período de estiagem prolongado e a falta de cercamento da área de estudo. Recomenda-se que o entendimento sobre a importância das matas ciliares deve ser melhor explorado com os proprietários das áreas a serem restauradas. Além disso, recomenda-se o uso de Senna alata (L.) Roxb., Bauhinia cheilantha, Inga edulis Mart., Libidibia ferrea (Mart. Ex Tul.) L.P. Queiroz, Clitoria fairchildiana R.A. Howard., como espécies resistentes às condições adversas semelhantes a este estudo, além do planejamento do plantio com uso do hidrogel, ou com a frequência já estabelecida de precipitação pluviométrica na área.
Ganacias de peso de bovinos en pastoreo en la epoca seca en el trópico de México
Authors: Quiroz Javier Francisco Enríquez , Aguilar Eduardo Daniel Bolaños , Islas Abraham Fragoso , Lagunes Maribel Montero , Vadillo Julio Cesar Vinay
Published: January 2024

El objetivo fue conocer el rendimiento de forraje y ganancias de peso de bovinos en pastoreo en una pradera de gramínea en monocultivo y en asociación gramínea-leguminosa en la época seca del año. El estudio se realizó en el Campo Experimental La Posta, en Medellín, Veracruz, México. En mayo 2018 se establecieron 4 hectáreas de praderas, 2 hectáreas  fueron para monocultivo, y 2 hectáreas para la asociación gramínea-leguminosa. Las especies establecidas fueron; Mombaza Megathyrsus maximus, Kudzú Pueraria phaseoloides y Clitoria ternatea. El pastoreo de becerros se realizó durante la época seca feb – mayo del 2020. Se empleó un pastoreo rotacional de 14/42 días de ocupación y descanso. Una vez estabilizado el pastoreo se inició con las evaluaciones. En los animales se evaluó la ganancia de peso vivo, y en la pradera la disponibilidad de materia verde seca de la gramínea (MVSG), la leguminosa (MVSL), material muerto (MMG), contenido de proteína, FDN, FDA, lignina y cenizas de los componentes antes descritos. Como resultados, las ganancias de peso de los animales no fueron diferentes (P>0.05) entre tratamientos, pero superiores a los 500 g/animal/día. La carga animal promedio fue 0.87 UA, lo cual fue acorde a la disponibilidad de forraje. No fue posible observar los beneficios que tienen las leguminosas en la producción animal, ya que la disponibilidad fue baja. La composición química de la biomasa fue similar entre tratamientos (P>0.05) el porcentaje de proteína cruda en la MVSG y MMG tuvo promedios de 7.86 y 3.07%, respectivamente y 12.86% la biomasa de leguminosa. Se concluye que el pasto Mombaza permitió importantes ganancias de peso de becerros en pastoreo (600 g/animal/día) en la época seca del año, aun cuando la disponibilidad de la leguminosa en la pradera fue baja.
Implementasi Green Accounting Dan Internal Corporate Governance Strength, Terhadap Sustainable Development: Csr Sebagai Variabel Moderasi
Authors: Wiguna Meilda , Hardi  , Eka Hariyani  , Devi Safitri
Published: January 2024

Penelitian ini menguji implementasi green accounting dan internal corporate governance strength terhadap sustainable development, dengan corporate social responsibility sebagai variabel moderasi. Populasi dalam penelitian ini adalah perusahaan textile dan garmen yang terdaftar di Bursa Efek Indonesia periode 2019-2021. Sampel penelitian yaitu 60 perusahaan textile dan garmen di Indoensia. Implementasi green accounting memasukkan unsur biaya lingkungan dalam pelaporan keuangan perusahaan yang sesuai dengan konsep sustainable development yaitu mengintegrasikan pertimbangan lingkungan, sosial dan ekonomi ke dalam strategi pembangunan untuk menjamin keutuhan lingkungan, keselamatan, efisiensi, kesejahteraan dan kualitas hidup generasi sekarang dan mendatang. Internal corporate governance strength atau tata kelola perusahaan memiliki empat prinsip yaitu transparansi, akuntabilitas, tanggung jawab dan keadilan operasional perusahaan yang dapat memenuhi kebutuhan sustainable development suatu perusahaan. Adannya Corporate Social Responsibility (CSR) membentuk komitmen perusahaan untuk berkontribusi dalam pengembangan ekonomi yang berbasis sustainable development. Analisis data yang digunakan yaitu Persial Least Square (PLS). Hasil penelitian ini menyatakan implementasi green accounting, internal corporate governance strength, berpengaruh terhadap sustainable development. Implementasi green accounting yang di moderasi oleh CSR berpengaruh terhadap sustainable development. sementara internal corporate governance strength yang di moderasi oleh CSR tidak berpengaruh terhadap sustainable development, dikarenakan internal corporate governance strength memiliki peran tersendiri untuk menunjang keberlanjutan perusahaan.
 
Kata kunci: Sustainable Development, Implementasi Green Accounting, Internal Corporate Governance Strength, Corporate Social Responsibility