bluuebunny/crossref_metadata_2025 huggingface dataset:
Sexual Dimorphism and Discrimination of Barbel Steed (Hemibarbus labeo) in the Jinhe River, China: An Indicator of Habitat Status
Authors: Li Jing , Tuo Yun , Xiao Tiaoyi , Chen Cuihe , Fang Guangwei
Published: January 2023

Sex identification is linked to sexual dimorphism and is an important study issue in fish biology and aquaculture. However, owing to the unmarked sexual heteromorphism between adult Hemibarbus labeo, it is often difficult to distinguish their sex by visual observation. This study aimed to find a simple and reliable morphometric criterion for the sex identification of H. labeo using discriminant models. Forty-two morphometric traits of sixty-eight H. labeo individuals collected from the Jinhe River were measured, and 41 standardized features were calculated and analyzed. Eight trait variables from 41 standardized attributes were screened using stepwise discriminant analysis. The total classification accuracy of the model was 95.59%. Twelve standardized features significantly differed between male and female H. labeo individuals (p < 0.05). The condition factor, body height, dorsal fin coxal length, the distance between the pelvic and anal fins, and body length were significantly greater in females than in males (p < 0.05), suggesting that females of H. labeo in the Jinhe River were plumper than males, with a larger body size, but a smaller caudal peduncle. These results implied that the sex identification of H. labeo can be performed using the discriminant equation established in this study. This study provides a theoretical basis for endangered fish species protection and their artificial propagation.
Assessment of the Impact of Industrial and Municipal Discharges on the Surface Water Body Status (Poland)
Authors: Wiesner-Sękala Marta , Kończak Beata
Published: January 2023

Due to potential pressure from industrial and municipal activities, urban water bodies are at risk of not achieving the environmental objectives of the Water Framework Directive (WFD) by 2027. This study comprised the quality assessment of water body “Kłodnica do Promnej (bez)” under a strong anthropogenic influence. The main potential sources of pollution in the catchment were identified and the related characteristic contaminants were analysed. The obtained values of pollutants were compared with the limit values for surface waters from Regulation (Journal of Laws 2021, item 1475). The results confirmed that the analysed water body located in highly urbanized area is characterized by poor water quality and chemical status below the good status. The main threat to the aquatic environment is high salinity associated with the presence of mine water discharges. Moreover, the priority substances, such as Cd, Ni and Pb, exceeded the environmental quality standards values (EQS) in most of the designated measurement points. Due to the fact that water ecosystems do not constitute stand-alone structures, but are included in a wider socio-ecological system, the implementation of an integrated approach to characterizing the existing status of the water bodies and estimating the risk posed to the aquatic ecosystem is a crucial element of the catchment management process in the context of the provisions of the WFD.
A Characterization of Graphs with Small Palette Index
Authors: Labbate Domenico , Mattiolo Davide , Mazzuoccolo Giuseppe , Romaniello Federico , Tabarelli Gloria
Published: January 2023

Given an edge-coloring of a graph G, we associate to every vertex v of G the set of colors appearing on the edges incident with v. The palette index of G is defined as the minimum number of such distinct sets, taken over all possible edge-colorings of G. A graph with a small palette index admits an edge-coloring which can be locally considered to be almost symmetric, since few different sets of colors appear around its vertices. Graphs with palette index 1 are r-regular graphs admitting an r-edge-coloring, while regular graphs with palette index 2 do not exist. Here, we characterize all graphs with palette index either 2 or 3 in terms of the existence of suitable decompositions in regular subgraphs. As a corollary, we obtain a complete characterization of regular graphs with palette index 3.
Origin of Homochirality: The Formation and Stability of Homochiral Peptides in Aqueous Prebiological Environment in the Earth’s Crust
Authors: Toxvaerd Søren
Published: January 2023

The oldest forms of living organisms on Earth are about 3.5 billion years old, and they are found in hydrothermal deposits, and it is often hypothesized that life originated there. However, hydrothermal systems with a fairly strong flow of chemical components are not the optimal place for the prebiological self-assembly of biomolecules and for the emergence of homochirality. This article examines the possibility that the self-assembly of homochiral molecules took place in an aqueous environment in the Earth’s crust. Based on the latest literature regarding the conditions in the lithosphere, there are several factors that point to the fact that the crust could be the location for the prebiological self-assembly of biomolecules, and there is nothing against it. The crust and the mantle contain a substantial amount of water, and at the time prior to the emergence of life, the crust most likely contained the necessary chemical substances for the synthesis of biomolecules and an aqueous environment where homochirality could be established.
Impact Attenuator Design for Improvement of Racing Car Drivers’ Safety
Authors: Itu Calin , Vlase Sorin
Published: January 2023

An essential element for driver safety is represented by the Impact Attenuator (especially for race cars). The effect of the Impact Attenuator can be seen in the behavior of a dummy, tied with a seat belt, in a frontal collision with a rigid wall. The loads that act on the dummy are determined and checked to see if they fall within the values recommended by existing standards. The car is considered a structure with a dummy fixed with a seat belt and equipped with an Impact Attenuator. Two types of Impact Attenuator having constructive similarity and symmetries are studied, made up of three different materials and different thicknesses of material. The behavior of the dummy was studied, considering a frontal collision of the car–dummy assembly, in accordance with existing standards. Using simulation software, the accelerations were determined at various points on the mannequin’s body and the force appearing on the seat belts was determined. The Gibbs–Appell equations are the method used to determine the dynamic response in this problem involving shocks.
Foreign Language Vocabulary Acquisition and Retention in Print Text vs. Digital Media Environments
Authors: Pikhart Marcel , Klimova Blanka , Ruschel Fanny Bohnenberger
Published: January 2023

In the context of very current trends in digital language education generally supported by governments and educational institutions, it seems necessary to evaluate the efficiency of these tools from various points of psycholinguistics and applied linguistics, mostly when it comes to learning a foreign/second language (L2). Therefore, this paper aims to evaluate vocabulary retention in L2 when using print text in contrast with digital media. The research was conducted among 122 participants who were university students and were divided into two groups to learn 60 new phrasal verbs; one group of them using a standard print text, the other using the same text displayed and annotated on their digital devices. There were two memory tests after four weeks of studying the four sets of phrasal verbs, i.e., 15 verbs a week, and another test after another month to evaluate students’ memory retention of the given vocabulary in time. The results clearly show a slight but clear discrepancy in these two groups in favor of the group using the print text in both tests performed. The findings of this study suggest that students can retain L2 vocabulary better in conditions where they have access to printed vocabulary and if they can make notes, highlight or write their translation in their native language. However, these findings should be verified from other perspectives as well to obtain more reliable data.
Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K+ Channel KV1.2 and Small- and Intermediate-Conductance Ca2+-Activated K+ Channels KCa2.2 and KCa3.1
Authors: Naseem Muhammad Umair , Gurrola-Briones Georgina , Romero-Imbachi Margarita R. , Borrego Jesus , Carcamo-Noriega Edson , Beltrán-Vidal José , Zamudio Fernando Z. , Shakeel Kashmala , Possani Lourival Domingos , Panyi Gyorgy
Published: January 2023

A novel peptide, Cm39, was identified in the venom of the scorpion Centruroides margaritatus. Its primary structure was determined. It consists of 37 amino acid residues with a MW of 3980.2 Da. The full chemical synthesis and proper folding of Cm39 was obtained. Based on amino acid sequence alignment with different K+ channel inhibitor scorpion toxin (KTx) families and phylogenetic analysis, Cm39 belongs to the α-KTx 4 family and was registered with the systematic number of α-KTx 4.8. Synthetic Cm39 inhibits the voltage-gated K+ channel hKV1.2 with high affinity (Kd = 65 nM). The conductance–voltage relationship of KV1.2 was not altered in the presence of Cm39, and the analysis of the toxin binding kinetics was consistent with a bimolecular interaction between the peptide and the channel; therefore, the pore blocking mechanism is proposed for the toxin–channel interaction. Cm39 also inhibits the Ca2+-activated KCa2.2 and KCa3.1 channels, with Kd = 502 nM, and Kd = 58 nM, respectively. However, the peptide does not inhibit hKV1.1, hKV1.3, hKV1.4, hKV1.5, hKV1.6, hKV11.1, mKCa1.1 K+ channels or the hNaV1.5 and hNaV1.4 Na+ channels at 1 μM concentrations. Understanding the unusual selectivity profile of Cm39 motivates further experiments to reveal novel interactions with the vestibule of toxin-sensitive channels.
Retrospective Modeling of the Omicron Epidemic in Shanghai, China: Exploring the Timing and Performance of Control Measures
Authors: Lou Lishu , Zhang Longyao , Guan Jinxing , Ning Xiao , Nie Mengli , Wei Yongyue , Chen Feng
Published: January 2023

Background: In late February 2022, the Omicron epidemic swept through Shanghai, and the Shanghai government responded to it by adhering to a dynamic zero-COVID strategy. In this study, we conducted a retrospective analysis of the Omicron epidemic in Shanghai to explore the timing and performance of control measures based on the eventual size and duration of the outbreak. Methods: We constructed an age-structured and vaccination-stratified SEPASHRD model by considering populations that had been detected or controlled before symptom onset. In addition, we retrospectively modeled the epidemic in Shanghai from 26 February 2022 to 31 May 2022 across four periods defined by events and interventions, on the basis of officially reported confirmed (58,084) and asymptomatic (591,346) cases. Results: According to our model fitting, there were about 785,123 positive infections, of which about 57,585 positive infections were symptomatic infections. Our counterfactual assessment found that precise control by grid management was not so effective and that citywide static management was still needed. Universal and enforced control by citywide static management contained 87.65% and 96.29% of transmission opportunities, respectively. The number of daily new and cumulative infections could be significantly reduced if we implemented static management in advance. Moreover, if static management was implemented in the first 14 days of the epidemic, the number of daily new infections would be less than 10. Conclusions: The above research suggests that dynamic zeroing can only be achieved when strict prevention and control measures are implemented as early as possible. In addition, a lot of preparation is still needed if China wants to change its strategy in the future.
Movement Protein Mediates Systemic Necrosis in Tomato Plants with Infection of Tomato Mosaic Virus
Authors: Liao Qiansheng , Guo Ge , Lu Ran , Wang Xiaoyi , Du Zhiyou
Published: January 2023

The necrogenic strain N5 of tomato mosaic virus (ToMV-N5) causes systemic necrosis in tomato cultivar Hezuo903. In this work, we mapped the viral determinant responsible for the induction of systemic necrosis. By exchanging viral genes between N5 and a non-necrogenic strain S1, we found that movement protein (MP) was the determinant for the differential symptoms caused by both strains. Compared with S1 MP, N5 MP had an additional ability to increase virus accumulation, which was not due to its functions in viral cell-to-cell movement. Actually, N5 MP, but not S1 MP, was a weak RNA silencing suppressor, which assisted viral accumulation. Sequence alignment showed that both MPs differed by only three amino acid residues. Experiments with viruses having mutated MPs indicated that the residue isoleucine at position 170 in MP was the key site for MP to increase virus accumulation, but also was required for MP to induce systemic necrosis in virus-infected tomato plants. Collectively, the lethal necrosis caused by N5 is dependent on its MP protein that enhances virus accumulation via its RNA silencing suppressor activity, probably leading to systemic necrosis responses in tomato plants.
Anti-Entry Activity of Natural Flavonoids against SARS-CoV-2 by Targeting Spike RBD
Authors: Meng Jie-Ru , Liu Jiazheng , Fu Lu , Shu Tong , Yang Lingzhi , Zhang Xueji , Jiang Zhi-Hong , Bai Li-Ping
Published: January 2023

COVID-19 is still a global public health concern, and the SARS-CoV-2 mutations require more effective antiviral agents. In this study, the antiviral entry activity of thirty-one flavonoids was systematically evaluated by a SARS-CoV-2 pseudovirus model. Twenty-four flavonoids exhibited antiviral entry activity with IC50 values ranging from 10.27 to 172.63 µM and SI values ranging from 2.33 to 48.69. The structure–activity relationship of these flavonoids as SARS-CoV-2 entry inhibitors was comprehensively summarized. A subsequent biolayer interferometry assay indicated that flavonoids bind to viral spike RBD to block viral interaction with ACE2 receptor, and a molecular docking study also revealed that flavonols could bind to Pocket 3, the non-mutant regions of SARS-CoV-2 variants, suggesting that flavonols might be also active against virus variants. These natural flavonoids showed very low cytotoxic effects on human normal cell lines. Our findings suggested that natural flavonoids might be potential antiviral entry agents against SARS-CoV-2 via inactivating the viral spike. It is hoped that our study will provide some encouraging evidence for the use of natural flavonoids as disinfectants to prevent viral infections.
Evaluation of Histone Demethylase Inhibitor ML324 and Acyclovir against Cyprinid herpesvirus 3 Infection
Authors: Matsuoka Shelby , Petri Gloria , Larson Kristen , Behnke Alexandra , Wang Xisheng , Peng Muhui , Spagnoli Sean , Lohr Christiane , Milston-Clements Ruth , Divilov Konstantin , Jin Ling
Published: January 2023

Cyprinid herpesvirus 3 (CyHV-3) can cause severe disease in koi and common carp (Cyprinus carpio). Currently, no effective treatment is available against CyHV-3 infection in koi. Both LSD1 and JMJD2 are histone demethylases (HD) and are critical for immediate-early (IE) gene activation essential for lytic herpesvirus replication. OG-L002 and ML324 are newly discovered specific inhibitors of LSD1 and JMJD2, respectively. Here, HD inhibitors were compared with acyclovir (ACV) against CyHV-3 infection in vitro and in vivo. ML324, at 20–50 µM, can completely block ~1 × 103 PFU CyHV-3 replication in vitro, while OG-L002 at 20 µM and 50 µM can produce 96% and 98% inhibition, respectively. Only about 94% inhibition of ~1 × 103 PFU CyHV-3 replication was observed in cells treated with ACV at 50 µM. As expected, CyHV-3 IE gene transcription of ORF139 and ORF155 was blocked within 72 h post-infection (hpi) in the presence of 20 µM ML324. No detectable cytotoxicity was observed in KF-1 or CCB cells treated for 24 h with 1 to 50 µM ML324. A significant reduction of CyHV-3 replication was observed in ~6-month-old infected koi treated with 20 µM ML324 in an immersion bath for 3–4 h at 1-, 3-, and 5-days post-infection compared to the control and ACV treatments. Under heat stress, 50–70% of 3–4-month-old koi survived CyHV-3 infection when they were treated daily with 20 µM ML324 in an immersion bath for 3–4 h within the first 5 d post-infection (dpi), compared to 11–19% and 22–27% of koi in the control and ACV treatments, respectively. Our study demonstrates that ML324 has the potential to be used against CyHV-3 infection in koi.
Dancing with the Devil: A Review of the Importance of Host RNA-Binding Proteins to Alphaviral RNAs during Infection
Authors: Westcott Claire E. , Isom Cierra M. , Karki Deepa , Sokoloski Kevin J.
Published: January 2023

Alphaviruses are arthropod-borne, single-stranded positive sense RNA viruses that rely on the engagement of host RNA-binding proteins to efficiently complete the viral lifecycle. Because of this reliance on host proteins, the identification of host/pathogen interactions and the subsequent characterization of their importance to viral infection has been an intensive area of study for several decades. Many of these host protein interaction studies have evaluated the Protein:Protein interactions of viral proteins during infection and a significant number of host proteins identified by these discovery efforts have been RNA Binding Proteins (RBPs). Considering this recognition, the field has shifted towards discovery efforts involving the direct identification of host factors that engage viral RNAs during infection using innovative discovery approaches. Collectively, these efforts have led to significant advancements in the understanding of alphaviral molecular biology; however, the precise extent and means by which many RBPs influence viral infection is unclear as their specific contributions to infection, as per any RNA:Protein interaction, have often been overlooked. The purpose of this review is to summarize the discovery of host/pathogen interactions during alphaviral infection with a specific emphasis on RBPs, to use new ontological analyses to reveal potential functional commonalities across alphaviral RBP interactants, and to identify host RBPs that have, and have yet to be, evaluated in their native context as RNA:Protein interactors.
PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future
Authors: Gokengin Deniz , Bursa Dominik , Skrzat-Klapaczynska Agata , Alexiev Ivailo , Arsikj Elena , Balayan Tatevik , Begovac Josip , Cicic Alma , Dragovic Gordana , Harxhi Arjan , Aimla Kerstin , Lakatos Botond , Matulionyte Raimonda , Mulabdic Velida , Oprea Cristiana , Papadopoulos Antonios , Rukhadze Nino , Sedlacek Dalibor , Sojak Lubomir , Tomazic Janez , Vassilenko Anna , Vasylyev Marta , Verhaz Antonija , Yancheva Nina , Yurin Oleg , Kowalska Justyna
Published: January 2023

With no expected vaccine for HIV in the near future, we aimed to define the current situation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central and Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited to respond to a 27-item survey including questions on PrEP (response rate 91.6%). PrEP was licensed in 68.2%; 95 centers offered PrEP and the estimated number on PrEP was around 9000. It was available in daily (40.1%), on-demand (13.3%), or both forms (33.3%). The access rate was <1–80%. Three major barriers for access were lack of knowledge/awareness among people who are in need (59.1%), not being reimbursed (50.0%), and low perception of HIV risk (45.5%). Non-occupational PEP was available in 86.4% and was recommended in the guidelines in 54.5%. It was fully reimbursed in 36.4%, only for accidental exposures in 40.9%, and was not reimbursed in 22.72%. Occupational PEP was available in 95.5% and was reimbursed fully. Although PrEP scale-up in the region has gained momentum, a huge gap exists between those who are in need of and those who can access PrEP. Prompt action is required to address the urgent need for PrEP scale-up in the CEE region.
Assessment of Groundwater Quality Using APCS-MLR Model: A Case Study in the Pilot Promoter Region of Yangtze River Delta Integration Demonstration Zone, China
Authors: Chen Zi , Zhou Quanping , Lv Jinsong , Jiang Yuehua , Yang Hai , Yang Hui , Mei Shijia , Jia Zhengyang , Zhang Hong , Jin Yang , Liu Lin , Shen Rujia
Published: January 2023

Groundwater contaminant source identification is an endeavor task in highly developed areas that have been impacted by diverse natural processes and anthropogenic activities. In this study, groundwater samples from 84 wells in the pilot promoter region of the Yangtze River Delta integration demonstration zone in eastern China were collected and then analyzed for 17 groundwater quality parameters. The principal component analysis (PCA) method was utilized to recognize the natural and anthropogenic aspects impacting the groundwater quality; furthermore, the absolute principal component score-multiple linear regression (APCS-MLR) model was employed to quantify the contribution of potential sources to each groundwater quality parameter. The results demonstrated that natural hydro-chemical evolution, agricultural activities, domestic sewage, textile industrial effluent and other industrial activities were responsible for the status of groundwater quality in the study area. Meanwhile, the contribution of these five sources obtained by the APCS-MLR model were ranked as natural hydro-chemical evolution (18.89%) > textile industrial effluent (18.18%) > non-point source pollution from agricultural activities (17.08%) > other industrial activities (15.09%) > domestic sewage (4.19%). It is believed that this contaminant source apportionment result could provide a reliable basis to the local authorities for groundwater pollution management.
Characterization of Sub-Catchment Stream and Shallow Groundwater Nutrients and Suspended Sediment in a Mixed Land Use, Agro-Forested Watershed
Authors: Gootman Kaylyn S. , Hubbart Jason A.
Published: January 2023

Excess nutrients and suspended sediment exports from agricultural watersheds are significant sources of global water quality degradation. An improved understanding of surface water and groundwater pollutant loads is needed to advance practices and policies. A study was conducted in an agricultural-forested catchment of the mid-Atlantic region of the United States. Stream water (SW) and shallow groundwater (SGW) samples were collected monthly between January 2020 and December 2021 from eight sub-catchment study sites. Samples were analyzed for nitrate (NO3-N), nitrite (NO2-N), total ammonia (NH3-N), total nitrogen (TN-N), orthophosphate (PO43-P), and total phosphate (TP-P) concentrations using spectrophotometric methods. Total suspended solids concentrations (mg/L) were quantified gravimetrically and volumetrically to estimate mean particle diameter (MZ, µm), particle surface area (CS, m2/mL), sample skewness (Ski), and particle size distributions (sand/silt/clay%). Results showed significant (p < 0.05) differences in nutrient concentrations and suspended sediment characteristics between SW and SGW between study sites. Differences were attributed to source water type and sub-watershed location. Principal components analysis indicated seasonal effects on water quality in summer months and connected land use with TSS, TN-N, and TP-P concentrations. Study results emphasize the importance of SGW water quality metrics for non-point source loading predictions to inform management decisions in agro-forested watersheds.
Comparison of Tool Steels for Tube End Flanging
Authors: Trautman Bence , Tóth László , Fábián Enikő Réka
Published: January 2023

One of the most important components of a tube end flaring machine is the flanging tool, which is subjected to mechanical stresses such as compression, bending and abrasion. It is therefore very important to choose the optimal material and manufacturing technology for the flanging tool. Böhler tool steel grades K110 and K340 were chosen as the subject of our research. Both materials were used to produce tube flanging tools, which were subjected to hardness testing, microscopic examination and surface wear testing after simple cooling or deep cooling and triple high temperature tempering after austenitisation in a vacuum at elevated temperature. Based on the measurements, the deep cooled and triple tempered K340 steel was found to be the most favourable tool steel for the production of the tube flanging tool.
Application-oriented use of Laser-induced Periodic Surface Structures
Authors: Windisch Márk , Maloveczky Anna , Aradi László , Veres Miklós , Fürjes Péter , Vida Ádám
Published: January 2023

This paper investigates the phenomenon of Laser-induced Periodic Surface Structures (LIPSS) on Si single crystals. As usual, by variation of parameters, the morphological and physical properties of the resulting surfaces can be tailored, with respect to their use in many applications. One application-oriented use of LIPSS is the preparation of SERS (Surface Enhanced Raman Spectroscopy) substrates, which can be used to detect extremely low concentrations of molecules. In this experimental work, a possible way of manufacturing of SERS substrates, followed by SERS enhancement testing has been shown.
THE EFFECT OF MANAGEMENT MOTIVATION AND COMPENSATION ON EMPLOYEE PERFORMANCE AT PT INHIL SARIMAS KELAPA
Authors: Okta Prianus Handro , Hendriani Susi , Chairilsyah Daviq
Published: January 2023

The research was conducted at PT Inhil Sarimas Kelapa. The aim is to determine the direct effect of the influence of motivation and management compensation on employee performance. This study took a sample of 115 employees. The variables used are management motivation and compensation and employee performance. The data were analyzed using SEM (Structural Equation Modeling) analysis which was operated through the Smart PLS 3.2.8 . program

The results showed that there is a positive and significant motivation on employee performance. Based on the results of the respondents' responses, it was found that the respondents had considered the motivation given by the company to have been carried out well. However, for indicators of recognition of the performance of getting higher wages and jobs that challenge the desire to learn to master the work in their field, improvements still need to be made, because the average respondent's response compared to other indicators has the lowest value. Compensation has a positive and significant effect on employee performance. Based on the results of the respondents' responses, it was found that the respondents had considered the compensation was good. However, it is necessary to pay attention to the Salary/Wage indicator because compared to other compensation indicators, respondents gave the lowest score. Motivation and compensation have a simultaneous positive effect on employee performance.
THE EFFECT OF COMPENSATION AND JOB SATISFACTION ON EMPLOYEE COMMITMENT AND LABOR TURNOVERAT PT. PARTNERS ATEDA SELARAS PANGKALAN KERINCI
Authors: Febriyana Olivia , Hendriani Susi , Samsir Samsir
Published: January 2023

This study aims to determine the effect of compensation and job satisfaction on worker commitment, to determine the effect of compensation and job satisfaction on workers' labor turnover, to determine the effect of compensation and job satisfaction on worker's labor turnover through commitment and to determine the effect of commitment to worker's labor turnover through commitment. . The population in this study were all workers of PT. Mitra Ateda Selaras, totaling 118 people. While the sample used as many as 118 people. The data used in this study were primary data and secondary data, while the data collection technique used a questionnaire. The data analysis technique used in this study is the data analysis used in this study is SEM. The results showed that compensation and satisfaction had an effect on employee commitment. Compensation and job satisfaction have an effect on employee labor turnover. Employee commitment has a significant effect on employee labor turnover. Compensation has a significant effect on employee labor turnover through employee commitment. Satisfaction has a significant effect on employee labor turnover through employee commitment.
TESTING THE EFFECT OF CUSTOMER CAPITAL AND TECHNOLOGICAL INNOVATION ON BUSINESS PERFORMANCE
Authors: Sudirman Acai , Hanika Ita Musfirowati , Halim Fitria , Julyanthry Julyanthry , Chandra Erbin
Published: January 2023

The digital era, which should be implemented and able to get high opportunities, can also become a threat if MSMEs keep their business the same. To face business competition that is now increasingly complex, every SME actor is required to be able to adapt to the company's external environment by continuously monitoring and managing customer capital and applying innovation in technology. This study analyzes and examines the effect of customer capital and technological innovation on business performance.This study uses a causality quantitative research design. The number of samples used in this study was 110 SME business actors. Data analysis used an instrument test, normality test, regression test, hypothesis test, and correlation test, as well as the coefficient of determination. The results of the data analysis confirm that customer capital and technology have a positive and significant impact on business performance. This research concludes that effective customer capital management and the readiness of SMEs to deal with rapidly changing technology are believed to impact business performance significantly. It can be implemented with a good idea that can be replicated more easily, requiring continuously new and better product usage methods, processes, and faster services
THE IMPORTANCE OF TEACHER WELFARE IMPROVEMENT
Authors: Fatria Mellio , Corrina Fatti , Zulammar Zulammar
Published: January 2023

In order to keep teachers with good skills and talents in the teaching process, well-being and compensation must be ensured. The well-being offered is very meaningful and useful to meet the physical and mental needs of teachers and their families. The aim is to maintain and improve the physical and mental condition of teachers so that morale improves and the quality of education improves with teacher welfare programs based on legal provisions, based on fairness and eligibility and organized by the government regulation. The form of teacher welfare is salary, such as compensation and basic salary and additional salary. The purpose of this study is to find out how teacher welfare affects the improvement of the quality of education. The type of research used in this research is qualitative research with a descriptive approach to document / text research.
IMPACT OF WORK FAMILY CONFLICT (WFC) ON ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) WITH PSYCHOLOGICAL WELL-BEING (PWB) AS MEDIATION
Authors: Khairi Said , Rahmat Adi , Abdillah Muhammad Rasyid
Published: January 2023

This study aims to investigate and explain theoretically and empirically the impact of WFC on OCB Employees. Furthermore, this study aims to investigate the PWB mechanism that influences or mediates the relationship. The location of this research was conducted at the Dinas Perkebunan of Indragiri Hilir Regency. The sample uses a census sampling technique because the population is relatively small. So that the sample used in this study amounted to 58 respondents. Analysis of research data was processed using Warp PLS software version 7.0 to analyze the data and determine the relationship between constructs. The results showed that WFC had a negative and significant effect on OCB, WFC had a negative and significant effect on PWB, PWB had a Positive and significant effect on OCB, while PWB has a negative and significant effect in mediating the relationship between WFC and OCB.
La enseñanza de las Tecnologías de la Información Geográfica orientadas al trabajo territorial e interactoral: empezar a ver la ciudad con otros ojos
Authors: Lucioni Nora , Rusler Verónica , Heredia Marina
Published: January 2023

Tradicionalmente las asignaturas de la Licenciatura de Geografía de la Universidad de Buenos Aires, y en especial las referidas a la enseñanza de Tecnologías de la Información Geográfica, han incluido propuestas aplicadas al ordenamiento territorial o a la evaluación ambiental. En la actualidad, han incorporado el trabajo colaborativo con otras instituciones y disciplinas para abordar problemáticas sociales a las que se enfrentan diariamente las personas que encuentran barreras en su movilidad como sucede con las personas con discapacidad y lxs adultos mayores. En este sentido, compartiremos las experiencias emanadas de un proyecto de trabajo colaborativo entre la Cátedra de Sistemas de Información Geográfica, el Programa de Discapacidad y Accesibilidad, en el cual participan integrantes de la Fundación Rumbos, que incluyó cuatro relevamientos, de momento presencial, sobre el estado de veredas, rampas y accesos a establecimientos públicos en los alrededores de la Facultad de Filosofía y Letras, y una instancia de relevamiento de campo durante la pandemia. Lxs estudiantes tuvieron, en las clases teóricas, una introducción al enfoque social sobre discapacidad y accesibilidad, luego trabajaron en la preparación de la salida a campo ajustando planillas, escalas de valores, utilizaron dispositivos de posicionamiento global (GPS), procesaron la información en un Sistema de Información Geográfica (SIG) incorporando categorías propias del análisis territorial y difundieron los resultados obtenidos en un geoportal web. La importancia de haber tenido la experiencia de trabajar con otras disciplinas junto con la Fundación Rumbos, y de utilizar sillas de ruedas o poder observar los desplazamientos de personas ciegas usuarias de bastón blanco durante los relevamientos a campo, cambió el modo en que lxs miembros de las cátedras y lxs estudiantes percibimos el espacio.
Memorias gustativas, familiares y colectivas: aportes para repensar la comensalidad de niños y niñas en comedores
Authors: Angeli María Julia , Huergo Juliana , Ibáñez Ileana D. , Simoni María Laura
Published: January 2023

En este artículo presentamos una serie de reflexiones emergentes de nuestra experiencia de trabajo durante el año 2019, en dos salas cuna localizadas en diferentes sectores (zona sureste y noroeste) de la ciudad de Córdoba, Argentina. Estos espacios están dedicados al cuidado de niños y niñas de entre cuarenta y cinco días y tres años, allí juegan, aprenden y comen. En este sentido era una preocupación de las cuidadoras la alimentación, por ello la propuesta consistió en abordar la comensalidad de manera conjunta con los actores que participan en la cotidianidad de estos espacios (equipo de docentes, auxiliares y cocinera, niños/as y grupos familiares) desde una perspectiva sociocultural, donde las memorias gustativas familiares fueron el eje de la intervención a partir de técnicas expresivo creativas. A partir de esta experiencia escribimos de forma conjunta con las familias recetarios colectivos como propuesta de abordaje participativo entre las instituciones y la comunidad.
Debates en torno al modelo universitario y la deserción estudiantil
Authors: Wauters Cuervo Alejandra
Published: January 2023

El presente artículo aborda la problemática de la deserción estudiantil que atraviesa a todo el nivel superior en la Argentina. Con relación a esto, se presentan las principales barreras y dificultades a tener en cuenta a la hora de abordar la permanencia y el egreso de la universidad, y cuál es el rol activo que deben asumir las instituciones educativas y el Estado para aportar a garantizar este derecho. Se reflexiona en torno al modelo universitario, desde la perspectiva de una Universidad al servicio de la sociedad, que busque ser inclusiva, transformadora y no autocentrada. Para ver aplicados estos conceptos, se presentará un dispositivo concreto impulsado por la Facultad de Filosofía y Letras de la Universidad de Buenos Aires (FFyL, UBA) que tiene como finalidad acompañar a estudiantes en su trayectoria educativa y evitar la deserción, el Taller de Apoyo Universitario (TAU). Este artículo se enmarca y es el resultado de la cursada del seminario de grado PST (Prácticas Socioeducativas Territorializadas): “El derecho a la universidad: estrategias interdisciplinarias en el taller de apoyo universitario del CIDAC-Barracas”, de la la FFyL, UBA.
Diazoxide and its Tautomers - A DFT Treatment
Authors: Türker Lemi
Published: January 2023

Diazoxide have several potential effectors that may potentially contribute to cardio protection. It is used to manage symptoms of hypoglycemia that is caused by pancreas cancer, surgery, or other conditions. It also acts as a non-diuretic antihypertensive agent. Diazoxide possessing various tautomeric forms should display variable biological properties depending on its tautomer content. It may exhibit 1,3- and 1,5-type proton tautomerism. Presently, all those possible tautomeric forms are considered. All the calculations have been performed within the realm of density functional theory with the constraints of B3LYP/6-311++G(d,p) level. All the tautomers are electronically stable and thermo chemically favorable formation values at the standard conditions. Some quantum chemical and spectral properties of those tautomeric systems as well as nucleus-independent chemical shift (NICS) values have been obtained and discussed.
The Genomics of Liposarcoma: A Review and Commentary
Authors: Beird Hannah , Lazar Alexander J. , Truong Danh
Published: January 2023

Soft tissue sarcomas STS are malignancies that show mesenchymal and neuroectodermal differentiation and thus most often resemble supportive and connective tissue including fat blood vessels muscle bone tendons and nerves Over 70 subtypes of sarcomas exist and pathologists have classified these broadly according to the degree to which they resemble differentiated cell types Figure 1 1 This review will focus on the most common subset of STS in adults liposarcoma which are tumors with histological features of specialized fat cells Liposarcoma are broken down into several subtypes The four with the highest incidence are welldifferentiated liposarcoma WDLPS dedifferentiated liposarcoma DDLPS myxoid liposarcoma MLPS and pleomorphic liposarcoma PLPS 1 Overall survival is highest for MLPS followed by WDLPS and DDLPS and then PLPS2-4 Figure 2 While WDLPS occurs predominantly in the deep soft tissues of the limbs and retroperitoneum DDLPS is located mostly in the retroperitoneum MLPS and PLPS are preferentially located within the limbs5 Despite these broad categories liposarcoma can also have mixed phenotypes and is often further subdivided into even more rare entities with other ultra-rare features For instance pleomorphic MLPS has attributes of both PLPS and MLPS6,7.
Sermaye Türleri ve Eğitim İlişkisi
Authors: ERDEM Burcu , AKCA Ümit
Published: January 2023

Günümüz dünyasında bilim ve teknoloji, siyaset, eğitim, askeri ve ekonomik alanda yaşanan hızlı gelişim ve değişimler klasik sermaye anlayışında da değişimlere sebep olmuştur. Bu anlamda daha önce sadece ekonomik anlamda ön plana çıkan sermaye kavramı da dönüşüme uğramış ve çok boyutlu olarak incelenmesi gereken bir hal almıştır. Günümüz toplumlarını, toplumsal yapıda meydana gelen değişimleri açıklamada özellikle sosyal, kültürel, entelektüel ve psikolojik sermaye kavramları ön plana çıkmıştır. Örgütsel anlamda beşeri bir kaynak olan insan kaynağına ve onunla ilgili sermaye türlerine yönelik araştırmalar hız kazanmıştır. Dünyada küresel ölçekte yaşanan değişim ve gelişmelerden temel bir toplumsal kurum olan eğitim kurumu da etkilenmektedir. Toplumda eğitim kurumunun etkinliği ve verimliliği sahip olduğu ekonomik, kültürel, sosyal, entelektüel ve psikolojik sermayelerine bağlıdır. Sermaye türleri açısından güçlü eğitim kurumlarına sahip olan toplumlar bilimsel teknolojik, askeri, sanatsal ve siyasi gelişmenin öncüsü konumundadır.
Inducing Positive Sorting through Performance Pay: Experimental Evidence from Pakistani Schools
Authors: Brown Christina , Andrabi Tahir
Published: January 2023

Attracting and retaining high-quality teachers has a large social benefit, but it is challenging for schools to identify good teachers ex-ante. This paper uses teachers’ contract choices and a randomized controlled trial of performance pay with 7,000 teachers in 243 private schools in Pakistan to study whether performance pay affects the composition of teachers. Consistent with adverse selection models, we find that performance pay induces positive sorting: both among teachers with higher latent ability and among those with a more elastic effort response to incentives. Teachers also have better information about these dimensions of type than their principals. Using two additional treatments, we show effects are more pronounced among teachers with better information about their quality and teachers with lower switching costs. Accounting for these sorting effects, the total effect of performance pay on test scores is twice as large as the direct effect on the existing stock of teachers, suggesting that analyses that ignore sorting effects may substantially understate the effects of performance pay.
Detector-Driven Classroom Interviewing: Focusing Qualitative Researcher Time by Selecting Cases in Situ
Authors: Baker Ryan Shaun , Hutt Stephen , Bosch Nigel , Ocumpaugh Jaclyn L. , Biswas Gautam , Paquette Luc , Munshi Anabil , Andres Juliana , Nasiar Nidhi
Published: January 2023

In this paper, we propose a new method for selecting cases for in situ, immediate interview research: Detector-Driven Classroom Interviewing (DDCI). Published work in educational data mining and learning analytics has yielded highly scalable measures that can detect key aspects of student interaction with computer-based learning in close to real-time. These measures detect a variety of constructs and make it possible to increase the precision and time-efficiency of this form of research. We review four examples that show how the method can be used to study why students become frustrated and how they respond, how anxiety influences how students respond to frustration, how metacognition interacts with affect, and how to improve the design of an adaptive learning system. Lastly, we compare DDCI to other mixed-methods approaches and outline opportunities for detector-driven classroom interviewing in research and practice, including research opportunities, design improvement opportunities, and pedagogical opportunities for teachers
Reducing the effects of the Ukraine war: analysis of increasing food imports from eco member states to azerbaijan
Authors: Huseynova Arzu Dogru qizi , Mammadova Arzu Imamverdi qizi , Abilova Arzu Sabir qizi , Hajikerimova Khatun Qedir qizi , Hasanova Heyran Rehim qizi , Mazanova Ophelya Idris qizi
Published: January 2023

The paper analyzes the stabilization of the situation in Azerbaijan against the background of rising food prices on world markets as a result of the war in Ukraine. The authors studied the effects of the Ukrainian war on the world and Azerbaijani import markets. Opportunities to replace the import of Azerbaijan’s largest importers Russia and Ukraine by ECO member states were analyzed. It was also investigated the question of whether OIC member states can be considered as an alternative markets. Analysis and evaluations were conducted to find answers to these and other similar questions. As a result, using the tools of the International Trade Centers such as the Market Access Map, Export Potential Map, etc., three member states of the Economic Cooperation Organization (Turkey, Kazakhstan, and Pakistan) with high potential for strategic food products for Azerbaijan have been identified. The article concluded the following: the war in Ukraine still continues to destabilize the world market. The Azerbaijan state should find alternative sources in a very short time.
The concept of organizing the work of research universities: prerequisites, tasks, recommendations for Ukraine
Authors: Balanchuk I. S.
Published: January 2023

Long before the emergence of modern research universities, in society, it became necessary to create educational institutions of an absolutely new type: with the latest approaches and methods to the principles of teaching; with mechanisms for mastering knowledge, modern by that time; with the structure of transferring acquired experience into practical activities. Thus, based on the conclusions of many specialists, scientists, teachers, it were developed and presented general and specific recommendations for the opening and development of such educational institutions, which we now call institutions of higher education of an innovative type, or research universities. The purpose of this article was to study the specifics of the functioning of research institutions by analyzing the features of the organization of their work, the main tasks, key problems and expected results of activities. The main scientific method used in this work was a system-analytical method, using which the main prerequisites for the creation of a research university were determined, as well as a holistic structure of the activities of such an institution of higher education in order to present practical recommendations for opening innovative institutions in Ukraine. The main results obtained in the course of this study can be identified as follows: determination of the characteristics of the “triple helix” model in the work of research universities; characteristics of the basic tasks, goals and problems in the work of such institutions; providing relevant proposals for the development of the concept of creating a research university in Ukraine. The results of this scientific work and the conclusions obtained in the course of the presented study can be used for further practical scientific research on this topic, as well as for: teachers and students of higher education in the specialty history, pedagogy, educational technology.
The activity of the enterprise in post-pandemic conditions
Authors: Parkhomenko V. D. , Lazarenko V. V.
Published: January 2023

The COVID-19 pandemic has become a big shock for the global and European economy. For the first time, world economies entered an epidemic crisis, which was not caused by the rules of market mechanisms, but by direct intervention in the work of enterprises related to health, the introduction of prohibitions and restrictions, which negatively affected the activities of enterprises, especially small and medium-sized businesses were affected. As a consequence of this natural phenomenon, nowadays there are practically no international recommendations for overcoming the consequences of the crisis. This fact demonstrated a clear lack of coordinating role of the main players, and, as a result, caused the introduction of unsystematic national response measures. The economic consequences of the impact of the epidemic crisis caused serious problems both on the supply side and on the demand side. The effectiveness of the work of enterprises both at the regional and national levels depend on their management system, especially in crisis situations. That is why the activities of enterprises should be considered together with the management system and the state of the environment. Enterprise activity is an integral function of the socio-economic system, and therefore requires the adaptation of each individual enterprise to the new requirements of the environment, to the corresponding changes, new logic and new principles regarding the functioning of the enterprise in the new conditions of the post-pandemic crisis, and therefore is important and relevant.