bluuebunny/crossref_metadata_2025 huggingface dataset:
Engajamento Comunitário, comunicação e saúde: estratégias de visibilidade dos pacientes renais
Authors: Muzi Daniela , De Albuquerque Melo Nogueira Fernanda , Antônio Afonso Bertoldo Lucilene , Sanjuan Ganem Prado Tatiana , Soares Guimarães Maria Cristina
Published: September 2021

A comunicação científica dialógica constitui a linguagem primordial do engajamento comunitário em pesquisa. O presente trabalho procura lançar um olhar exploratório às estratégias de engajamento ente ciência e sociedade no campo da pesquisa em saúde no Brasil. O estudo de caso da Associação dos Doentes Renais e Transplantados do Estado do RJ (Adreterj) revelou que o grupo busca o exercício do controle social, porém, há subaproveitamento da comunicação e pouco engajamento comunitário em pesquisa.A comunicação científica dialógica constitui a linguagem primordial do engajamento comunitário em pesquisa. O presente trabalho procura lançar um olhar exploratório às estratégias de engajamento ente ciência e sociedade no campo da pesquisa em saúde no Brasil. O estudo de caso da Associação dos Doentes Renais e Transplantados do Estado do RJ (Adreterj) revelou que o grupo busca o exercício do controle social, porém, há subaproveitamento da comunicação e pouco engajamento comunitário em pesquisa.
Automatizando a estética: inteligência artificial e cultura das imagens
Authors: Manovich Lev
Published: September 2021

O artigo apresenta um panorama de pesquisas recentes que empregam a inteligência arti cial para o estudo da cultura. A partir de exemplos relacionados à produção e recepção de imagens, sons e textos, são avaliadas as tendências promissoras e as limitações das metodologias quantitativas. São abordadas tanto as produções pro ssionais, quanto os conteúdos gerados por usuários das mídias sociais. Sugere-se a partir disso o paradigma denominado Análise Cultural.
Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia
Authors: Moradi Tabriz Hedieh , Nazar Elham , Jazayeri Fatemeh , Javadi Arezoo Eftekhar
Published: September 2021

Introduction: COVID-19 infection prompts inflammatory responses and acute lung injury in human beings. Complete blood count with differential is essential investigative tool in its managing. However, very few studies revealed the variations of blood cell morphology in this disease.Case report: We reported a 39-years- old female patient complained of respiratory distress one week prior to hospitalization. The patient suffered from cough, fever, and molecular test was reported positive for COVID-19 infection. Laboratory data revealed severe permanent leukopenia and peripheral blood smear examination showed blastoid cells after remission of respiratory signs. Patient underwent bone marrow biopsy for rule out acute myeloid leukemia. But, on bone marrow sample, only viral cytopathic effects were seen. COVID-19 virus stimulates inflammatory cells to produces various inflammatory cytokines and as a result, viral cytopathic effects on white blood cells is seen. Conclusion: We have described how the characteristic peripheral blood findings of COVID‐19 infection can be misinterpret as acute myeloid leukemia.
PTBD During COVID-19 Pandemic: A Life Saving Procedure in Malignant Obstructive Jaundice Patients
Authors: Rani Khushboo , Gaurav Kumar , Kumar Naveen
Published: September 2021

Objective: PTBD is an important lifesaving alternative for biliary tract decompression to endoscopic drainage in the treatment of malignant obstructive jaundice patients. The aim of this study was to evaluate the usefulness of PTBD in terms of the relief of symptoms and laboratory data, survival after PTBD, and the relationship between patient characteristics and survival during COVID-19 pandemic. Methods: During this study, in total thirteen patients’ procedures of percutaneous drainage were applied during a three-month period. The average age of men was 59 years and women was 55 years. The causes of obstructive jaundice were investigated using both abdominal computed tomography and abdominal ultrasonography. Results: In examined group percutaneous drainage was successful in 92.3% (12 patients) and drainage procedure application was ineffective in 7.7% (1 patient). After PTBD, almost all the symptoms of obstructive jaundice were relieved, except in one patient. Transient haemobilia was the only complication seen in one patient. Conclusion: In present scenario of COVID-19 pandemic, PTBD emerges as an effective method of biliary tract decompression and an important alternative to endoscopic drainage. It decreased the jaundice and relieved the symptoms caused by biliary tract obstruction. Thus, our study shows a positive impact in quality of life of patients after PTBD.
Infection Control and Modified Workflow Strategies in Radiation Oncology Department during COVID 19 Crisis: An Institutional Experience
Authors: Soni Sweta , Solanki Akanksha , Pareek Puneet , Vyas Rakesh Kumar , Manna Sumanta , Gayen Sanjib
Published: September 2021

Purpose: To build safe environment for cancer fighters and radiation personnel during COVID-19 pandemic by focusing on infection control, workflow and radiotherapy dose schedules modification strategies in radiation oncology departments. Material and Methods: A meeting was called post lock down in radiation oncology department to prepare infection control policies and workflow strategies in time of COVID-19 Pandemic.Results: Strategies and policies were formed during COVID-19 crises taking following points into consideration 1) Infection control policies 2) CT simulation policies 3) Day care admission and chemotherapy administration policies 4) Radiation treatment plan modification and delivery strategies 5) Brachytherapy delivery strategies.Conclusion: Management of cancer patients is an issue running parallel to the present condition of COVID-19 pandemic. Further randomized trial on hypofractionated radiotherapy schedules should be encouraged. Positivity, awareness and systematic approach are most important step in balancing the current scenario.
Antibiotic Cefepime with Antacid, Metal Complexation studied by UV Spectrophotometrically in addition to Exploration of Antimicrobial Activity, In-Vitro Demonstration
Authors: Nayeem Uddin Md. , Anisul Islam Md. , Md. Thousif Akif , Akter Suraiya , Sufria Kaniz Humaiya , Shahidul Islam Md.
Published: September 2021

As a fourth generation of cephalosporins, cefepime shows very superior activity in opposition to gram - negative organisms like Pseudomonas aeruginosa in addition to gram – positive organisms like Staphylococcus aureus. It is very functional in the lower respiratory tract infection reasoned by Influenza, Aureus, Pneumonia as well as Urinary tract infections caused by the E. Coli, skin in addition to skin structure infections reasoned by S. epidermidis in addition to intra-abdominal infection. The principal rationale of present follow a line of the exploration was to search in vitro interactions of the cefepime with key metal salt also antacid to settle on the bioavailability in view of antimicrobial movement of cefepime following drug metal communications at the pH7.4. Cefepime is one of the cephalosporin drugs so as to be exercised to treat numerous different sorts of infections originated by bacteria. Since the existence of compelling the ligand may influence bioavailability of metal in blood and tissues, for that reason with the intention of study the handy interaction of the cefepime with vital elements in attendance in the body. Cefepime has been related with Zn, Mg as an in-vitro examination. Besides, the anti-microbial movement of drug along with the complexes was resolved. It has scrutinized that cefepime interrelates with metal and antacid on the pH 7.4 by plotting various uv spectrophotometric methods. This examine authenticates that there was the interaction between cefepime and metal, antacid which was authenticated by job’s plot technique furthermore by antimicrobial exploration. This was authenticated that region of inhibition of cefepime with Metal in addition to antacid condensed from 16 mm to 13 mm and 14 mm correspondingly. The typical cefepime disk also checked in opposition to Staphylococcus aureus.
Review of Toxicity of Allicin from Garlic
Authors: Alare Kehinde
Published: September 2021

Allicin components of garlic has been helpful medicinally but adverse effects has been noticed with excessive usage of garlic supplements. The toxicity of the garlic supplements has been carefully reviewed in this article. These toxicities has been linked to its effects and autonomic nervous system and its bactericidal functions. These research also encouraged usage of allicin supplements pills with regulated dosage to garlic concoction taking in most African communities.
Protein Staining and Analysis with Artificial Intelligence Color Algorithm Analysis with 2-Dimensional Inkjet Printer to Identify Covid-19 Adhesion and Infected Properties on Artificial Body Fluid
Authors: Eyupoglu Ozan
Published: September 2021

In this study, the predictive modeling of Covid-19 viral contamination on artificial body fluids (simulated lung fluid, perspiration, saliva, and urine) was done by colorimetric analysis of protein staining on paper ground with henna ethanolic extract loaded on a 2-dimensional printer cartridge. The purchased artificial body fluids were left in the open-air atmosphere of sterile containers to the public places of pandemic hospitals, pharmacies, which are the most frequent places of Covid-19 patients for 2 weeks. These body fluids, which were then thought to be Covid-19 adsorption, were safely collected and placed in the cartridge chambers of the 2-D printer. The mixtures of artificial body fluids and henna plant extract in the cartridges were sprayed on the paper floor by ink painting. The algorithmic matrix code system was created by colorimetric predictive scaling between +1 and -1 about the images of viral transmission to artificial body fluids taken with a smartphone.
Demonstration of Phytochemicals and In-vitro Antioxidant and Anti-inflammatory activity by methanolic extract of Elettaria cardamomum
Authors: Islam Md. Shahidul
Published: September 2021

The existing research study attempts to untie novel avenues for development of the medicinal exercises of Elettaria cardamomum, fashionable known as the “Queen of Spices” and locally recognized as “elaichi”. Its seeds are utilized as abortifacient, acrid, alexiteric, aromatic, sweet, cardiac tonic, cooling, carminative, digestive, diuretic, expectorant, stimulant and also tonic beneficial in the asthma, haemorrhoids, bronchitis, strangury, renal in addition to vesical calculi, anorexia, halitosis, gastropathy dyspepsia as well as burning sensation. The prime goal of this research work is to evaluate antioxidant as well as anti-inflammatory properties of the traditional Bangladeshi medicinal extracts in addition to examine these activities. The aim in present work was to screen the phytochemical profile as well as pharmacological activities of the methanolic extract of this plant’s leaves. To explore pharmacological actions DPPH scavenging test and the HRBC membrane stabilization techniques were done for the antioxidant and also anti-inflammatory test respectively. The pharmacological works revealed that plant extracts might have noteworthy antioxidant effect which is possibly mediated by the inhibition of DPPH free radical which is accountable for oxidation. The IC50 values by the DPPH scavenging test observed for the standard and the leaves were 106.38µg/ml & 594.47µg/ml respectively. There is also moderate anti-inflammatory activity. The IC50 values for anti-inflammatory activity by standard & leaves were 35.04µg/ml and 944.0 µg/ml respectively.
Lockdown Ends Sex Returns Monkey Survey of Totally Less Sunlight Pharmacy Instituting Privately Extra pure
Authors: Hajare Rahul
Published: September 2021

With Unlock 5 underway and life moving back to a semblance of past normality, interactions among love birds have moved up a notch. Having to cope up with their partners for months in a closed space due to the lockdown, the excitement from a change of scenery has proved sexually alluring for some. According to a study conducted by Gleeden sitting, an extramarital dating platform, more than 60 percent of respondents confessed that the lockdown had a negative impact on their relationship, both emotionally and physically. To understand what men and women did to feel desirable, 2,000 users from Delhi, Satara, Thane, Hyderabad, Goa, Kolkata and Pune have polled between second extended June 25 and October 15, 2020. The Gleeden sitting survey revealed that 37 percent of it has users had an affair with colleagues after getting back to their offices following the lockdown. Getting back to work not only meant returning to socialising in an office environment, but also a chance for irresistible dalliances dialysis with co-workers. When quizzed about their reason behind these encounters, 37 percent confessed that it has due to a pure craving for sex smell. 33 percent of users said they enjoyed someone other than their partner chest pain finding them attractive. About 30 percent of them said they cheated to feel desirable again next level.
Cochliobolus, Drechslera, Bipolaris, Curvularia different nomenclature for one potent fungus
Authors: A. Elkhateeb Waill , AL Kolaibe Abdu Ghalib , M. Daba Ghoson
Published: September 2021

Cochliobolus is a Dematiaceous fungi that belong to family: Pleosporaceae. It is known as worldwide pathogen of mostly grasses that caused devastating disease epidemics of important economic food crops as wheat, rice, and maize. Many Cochliobolus species have their asexual states, and consequently synonyms, in either Bipolaris or Curvularia. In this review, highlights were presented on Cochliobolus species as models of fungi rich in therapeutic agents that can be employed in different applications. Moreover, describing the importance and potentials of this fungus in order to encourage for further studies to search, isolate, and purify already known metabolites. Also, screen for, and discover novel metabolites produced by those potent fungi in order to be involved in additional applications.
Analisis Risiko Rantai Pasok Dengan House of Risk di PT. Petrogas Prima Service
Authors: Riskiana Wulan , Aman Moehamad , Rifa'i Affan
Published: September 2021

Perkembangan manajemen rantai pasok menfokuskan pada kajian tentang efektifitas dan efisiensi aliran barang, sistem informasi dan aliran keuangan sehingga mencakup semua rantai pasok dengan semua pihak yang bersangkutan. Salah satu permasalahan yang dihadapi dalam PT Petrogas Prima Services perusahaan repair tabung gas LPG volume 3 kg adalah keterlambatan kedatangan material. Pada pengiriman sealtape hanya 97,4% dari pemesanan, Pada pemesanan valve melebihi hari pengiriman dan pada saat distribusi terdapat kendala yang tidak bisa diprediksi. Oleh kerena itu, dibutuhkan manajemen rantai pasok untuk koordinasi dan mengelola aktifitas rantai pasok supaya proses produksi berjalan dengan baik dan tidak ada keterlambatan produksi maupun distribusi. Penelitian ini dilakukan untuk menganalisis risiko pada aktivitas rantai pasok mengunakan metode House of Risk. Dari House of risk fase I menghasilkan 5 penyebab risiko dominan yaitu gangguan teknis (mesin tidak optimal), karyawan kurang teliti, perencanan kurang maksimal, babhan baku tidak sesuai dan system informasi yang tidak efektif. Melalui House of Risk Fase II dihasilkan 13 langkah aksi pencegahan yang direkomendasikan bagi perusahaan untuk mengurangi potensi kejadian risiko, yaitu melakukan pemeriksaan rutin (PA2), melakukan pencegahan (PA4), menyusun SOP perawatan (mesin/transportasi) (PA1), pembagian sift kerja yang sesuai (PA5), menejemen persediaan sperpart mesin (PA3), pengendalian bahan baku (PA11), pengadaan training (PA6), menyusun SOP pengadaan (inventory) dan supplier (PA8), meningkatkan pengelolaan terhadap menenjemen (PA9), menyusun alternative perencanaan (PA10), pelatihan (PA13), pemberian sangsi disiplin (PA7), dan dukungan software (PA12).
Professor Agnieszka Draber-Mońko 1931–2018
Authors:   Museum and Institute of Zoology PAS, Wilcza 64, 00-679 Warszawa, MIKOŁAJCZYK Waldemar
Published: September 2021

The article presents the silhouette and scientific achievements of Polish dipterologist, Agnieszka Draber- Mońko, who researched the systematics, morphology and bionomy of parasitic flies. A list of publications and described taxa has been included.
New records including new species of Megaselia Rondani and Triphleba Rondani (Diptera: Phoridae) from Finland
Authors:   Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, U.K., DISNEY R. Henry L. , WINQVIST Kaj
Published: September 2021

Eleven new records of Phoridae from Finland and eight new species of Megaselia Rondani. M. confusus n. sp., M. eeroi n. sp., M. horrenticauda n. sp., M. kajaaniensis n. sp., M. miroparaphysis n. sp., M. necrubida n. sp., M. turkuensis n. sp., M. utsjokiensis n. sp. plus the hitherto unknown female of Triphleba aequalis (Schmitz) and Triphleba cumsetae n. sp. are presented.
Aphid species (Hemiptera: Aphididae) new in the fauna of the Eastern Beskid Mountains (southern Poland)
Authors:   Department of Zoology, Faculty of Biology and Environmental Protection, University of Silesia, Bankowa 9, 40-007  Katowice, Poland, KASZYCA Natalia , MORAWSKI Miłosz ,   Department of Zoology, Faculty of Biology and Environmental Protection, University of Silesia, Bankowa 9, 40-007  Katowice, Poland, TASZAKOWSKI Artur ,   Department of Zoology, Faculty of Biology and Environmental Protection, University of Silesia, Bankowa 9, 40-007  Katowice, Poland, DEPA Łukasz ,   Department of Zoology, Faculty of Biology and Environmental Protection, University of Silesia, Bankowa 9, 40-007  Katowice, Poland
Published: September 2021

Fifteen aphid species were found in the Eastern Beskid Mountains for the first time during the short faunistic study. Currently, 119 aphid species are recorded from this region, which may still constitute only a fraction of the fauna of neighboring regions and testify to an insufficient faunistic study on aphids.
First records of some Oribatid mite species (Acari, Oribatida) from Ukraine
Authors:   State Museum of Natural History, National Academy of Sciences of Ukraine, Teatralna Str., 18, Lviv, 79008, Ukraine, HUSHTAN Habriel H.
Published: September 2021

Four species of oribatid mites known mainly from central Europe: Oppiella hygrophila (Mahunka, 1987), Oxyoppia europaea Mahunka, 1982, Achipteria cf. quadridentata Willmann, 1951 and Ceratozetes cf. psammophilus Horak, 2000 are recorded from Ukraine for the first time. The new records of the first three species extend the known areas of their occurrence to the east of Europe (Zakarpattia region).
Albino clutch of moor frog Rana arvalis – a rare observation from Poland
Authors:   Institute of Zoology, Poznan University of Life Sciences, Wojska Polskiego 71 C, 60-625, Poznań, Poland, KACZMARSKI Mikołaj , KACZMAREK Jan M. ,   Institute of Zoology, Poznan University of Life Sciences, Wojska Polskiego 71 C, 60-625, Poznań, Poland
Published: September 2021

Moor frog Rana arvalis is widespread in Poland and its geographic range spans from Central Europe up to Siberia, but any records of albinism are rare in the species. Freshly laid albino spawn of moor frogs was observed during nocturnal fieldwork near the village of Lubosz, north-western Poland, in spring 2016. We noted the further development of eggs, but no albino tadpoles nor metamorphs were found later during the season. Both albinism and transient albinism have been noted in the species, this being the first observation from Poland. Atypical pigmentation impairs cryptic function of body colouring and might affect survival. The observation comes from a large frog population in a relatively undisturbed habitat, and thus it adds to the body of literature concerning the background level of abnormalities in amphibian populations.
New data on the Afrotropical Xantholinini. 2. Six new species of Metocinus Cameron, 1950 (Coleoptera, Staphylinidae)
Authors:   Museo di Storia Naturale dell'Università di Firenze, Sezione di Zoologia “La Specola” Via Romana 17, I-50125 Firenze, Italy, BORDONI Arnaldo
Published: September 2021

Six species of the genus Metocinus, which is one of the most characteristic and widespread in central Africa, i.e. M. szujeckii n. sp. (Zaire), M. angustus n. sp. (Uganda), M. ibadan n. sp. (Nigeria), M. ugandensis n. sp. (Uganda), M. capitatus n. sp. (Uganda), M. uzungwa n. sp. (Tanzania) are described and illustrated. With the six species here described, the taxa of this genus, endemic to Africa, add up to 88.
The use of learning management system (LMS) moodle in the midst of covid-19 pandemic: Students’ perspective
Authors: QUANSAH Rebecca , ESSIAM Charles
Published: September 2021

This study reports on students’ acceptance of Learning Management System (LMS) Moodle as e-Learning system at the University of Education, Winneba. The participants of the study were 392 undergraduate students purposively selected from the Department of Integrated Science Education. Technology Acceptance Model (TAM) instrument which has four factors; Perceived Usefulness, Perceived Ease of Use, the Behavioural Intention, and the Actual Use was the main instrument employed to collect the data. Findings from the descriptive analyses of data collected revealed a considerable high acceptance of the LMS Moodle by students. Although challenges like internet connectivity and lack of prompt feedback from lecturers were reported, students found the LMS Moodle as convenient and user-friendly. To promote effective teaching and learning in future, virtual learning should be integrated into the normal traditional classroom.
Діджиталізація міжнародних економічних відносин: розвиток електронної торгівлі
Authors: Дмитрієва Наталія
Published: September 2021

Досліджено теоретичні й прикладні положення діджиталізації міжнародних економічних відносин на основі розвитку електронної торгівлі в національній економіці. Узагальнено й систематизовано дефініційно-методологічні аспекти тлумачення сутності й генезису електронного бізнесу. Здійснено емпіричний аналіз проблем розвитку електронної торгівлі та їх рішень у різних країнах світу. Зокрема, охарактеризовано механізми роботи систем е-торгівлі в ЄС і оцінено можливості їх застосування на вітчизняному ґрунті. Подано рекомендації щодо активізації е-торгівлі в Україні через застосування інституційно-організаційних і правових механізмів, що передбачає імплементацію європейського інструментарію. Рекомендовано економістам, фахівцям зі сфери електронної торгівлі, підприємцям-практикам, юристам.
Інвестиційно-інноваційне забезпечення промисловості України в умовах Четвертої промислової революції
Authors: Кириченко Оксана
Published: September 2021

У монографії висвітлено теоретико-методологічні підходи до вирішення актуальних проблем інвестиційно-інноваційного забезпечення промисловості України в умовах Четвертої промислової революції. Досліджено етапи промислового розвитку та узагальнено тенденції технологічно-промислового еволюціонування. З’ясовано змістовно-типологічні характеристики інвестиційно-інноваційного забезпечення промисловості. Обгрунтовано необхідність формування та впровадження механізму інвестиційного забезпечення інноваційного розвитку промисловості. Розроблено концептуальні та методологічні засади інвестиційно-інноваційного забезпечення промисловості України на засадах «Індустрії 4.0». Обґрунтувано шляхи удосконалення державної промислової політики як інституційного базису інвестиційно-інноваційного забезпечення промисловості країни. Розроблено комплекс державних цільових програм розвитку промисловості України на засадах «Індустрії 4.0». Монографія розрахована на широке коло працівників органів державного управління, науковців, фахівців у сфері промислового розвитку, викладачів, аспірантів та студентів закладів вищої освіти.
efeito da propaganda na internet sobre a intenção de compra dos consumidores:
Authors: Vieira Paulo Roberto da Costa , Morais  Oliveira Hermano Henry , Magalhães da Silva Antonio Carlos
Published: September 2021

O presente estudo objetiva avaliar se atitudes e crenças influenciam, no caso brasileiro, as intenções de compra dos consumidores, admitindo que eles não se restringem a alcançar a curva de preferências mais elevada, com dada renda monetária, conforme postula a Microeconomia. Para tanto, utilizou-se o modelo de Saadeghvaziri, Dehdashi e Askarabad (2013), o qual emprega modelagem de equações estruturais, com base em mínimos quadrados parciais. Realizou-se pesquisa de survey, com aplicação de questionário estruturado, constituído de opções de resposta em consonância com a escala Likert. A amostra de conveniência foi composta de 124 profissionais de distintas formações com experiência em comércio eletrônico. Os resultados exibiram significância estatística e atestaram que a intenção de compra é influenciada por atitudes e crenças.
Business Startup and Entrepreneurship: Canada
Authors: Pauley Matthew
Published: September 2021

Given the financial challenges students face in higher education, my hope with this textbook is to draw on my 20+ years of entrepreneurship experience and academic research to compile resources that reflect the general aspects of starting a business. Business Startup and Entrepreneurship: Canada is an Open Educational Resource (OER) textbook that focuses on the practical, current, and relevant topics associated with starting a business in Canada. This broad practical approach allows instructors to introduce these simple chapters to build a basic understating of the essentials to startups. Along with this textbook is an accompanying Business Plan Workbook, helping students to work through a business idea chapter-by-chapter that hopefully culminates in a well thought-through startup plan. In my experience teaching introductory entrepreneurship courses, developing a business plan supports deep-level learning that is displayed through critical analysis, creativity, and networking. The design of the business plan has been simplified and tested over the past three years with over 750 students from diverse cultures and academic disciplines. It is my recommendation that students work on the business plan throughout the duration of the course as they complete chapters to reaffirm important lessons. Students may find tasks such as finance and accounting difficult, which is why an Excel Worksheet accompanies the business plan to help prepare financial reports for their proposed businesses.
Business Startup and Entrepreneurship: Canada Workbook
Authors: Pauley Matthew
Published: September 2021

Business plan workbook that accompanies the textbook: Business Startup and Entrepreneurship: Canada.
An unusual case of acute abdomen: bilateral ovarian veins thrombophlebitis
Authors: Oprisan A. , Barreda Solana M.
Published: September 2021

Postabortion ovarian vein septic thrombophlebitis is a very rare variety with high complication rates and it should be considered as a differential diagnosis for febrile abdominal pain syndrome in the post-abortion period. The contrast-enhanced CT or MRI have the highest sensitivity and specificity to diagnose the ovarian veins thrombi. The treatment it consists in a combination of anticoagulation therapy and antibiotics. In case that anticoagulation is contraindicated it´s recommended placing an inferior vena cava filter.
Nodal tuberculosis on positron emission tomography/computed tomography with 18F-Fluordexosiglucose, a case report
Authors: Meneses Navas M.K. , Romero Fernández P. , Cabrera Martín M.N. , Ortega Candil A. , Carreras Delgado J.L.
Published: September 2021

Tuberculosis is an infectious disease, caused by the Mycobacterium tuberculosis bacillus. Extrapulmonary disease can cause nonspecific symptoms and signs, which makes diagnostic suspicion difficult.
We present the case of a man with a history of cancer in complete remission, diagnosed with lymph node tuberculosis, after being admitted to our hospital due to fever, dyspnea, and central chest pain. A Positron Emission Tomography / Computed Axial Tomography with 18F-fluordexosiglucose is requested; which showed multiple mediastinal adenopathic conglomerates with intense radiotracer uptake, suggesting ruling out malignancy.
Active lymph node tuberculosis will show increased metabolic activity with Positron Emission Tomography / Computed Tomography with 18F-fluordexosiglucose, which could make the differential diagnosis with malignant tumors or other granulomatous diseases difficult, as in the case of our patient. Therefore, it is important to consider lymph node tuberculosis as a differential diagnosis in patients with adenopathies suspected of malignancy.
Pulmonary hypertension. Clarifying concepts
Authors: de Berrazueta Fernández J.R.
Published: September 2021

Pulmonary Arterial Hypertension is a central syndrome produced by a large number of cardiological, pulmonary, and systemic diseases that affect the lung bed. It is defined by the existence of a pulmonary artery systolic pressure greater than 30 or a mean pressure greater than 25 mmHg. This definition criterion has been maintained for more than 60 years. However, the current classification includes two concepts: a Pulmonary Arterial Hypertension (PAH) with two groups of disorders in which only pulmonary arterial resistance increases and five groups that are classified as Pulmonary Hypertension (PH): PH Secondary to Pulmonary Veno-occlusive Disease , HP secondary to diseases of the left side of the heart; HP Obliterative diseases and pulmonary hypoxemia; HP Pulmonary thrombus occlusive diseases, and a group of multifactorial HP. The difference is found in how the different diseases affect the pulmonary vascular bed, and how they alter the physiology or behavior of pulmonary resistance, which are the concepts that must be handled when talking about this syndrome and whose structural changes and management we will discuss in a later article.
Determinants of selective neuronal vulnerability in Parkinson's disease
Authors: López-González del Rey N. , Blesa J. , Obeso J.A.
Published: September 2021

Parkinson´s disease (PD) is the second most frequent neurodegenerative disease affecting the population older than 65 years old. This incidence will greatly increase due to the progressive aging of the population in the coming years. PD diagnosis is made when there is a 50-60% dopaminergic cell loss in the substantia nigra pars compacta (SNc) and the striatal dopamine loss reaches around 70-80%, coinciding with the onset of classical parkinsonian motor signs: tremor, rigidity and slowness of movement. A significant proportion of patients present non-motor symptoms, generally associated to disfunction of non-dopaminergic regions, which can appear before, around or after diagnosis (10-15 years). Therefore, in PD both dopaminergic and non-dopaminergic groups are affected, but the motor manifestations are the main reason for consultation and causes the greatest disability for many years.
There is a large heterogeneity within dopaminergic neural groups in terms of morphology, metabolism, molecular pattern, protein accumulation, inflammation levels, protein expression, etc. In this review we discuss different factors that could explain the special vulnerability of certain dopaminergic neurons in the SNc. Knowledge on the mechanisms and underlying factors of this selective vulnerability of the ventrolateral dopaminergic neuros of the SNc is essential for developing neuromodulatory and/or neuroprotective therapies, leading in turn to halt or modify the neurodegenerative process in PD.
The doctor-patient relationship in the light of telemedicine
Authors: Castellano Arroyo M.
Published: September 2021

The doctor-patient relationship was the origin of Medicine and after more than 40 centuries, the medical act, with its important changes, is still the centre of this Medicine that is, more than ever, science and art. Knowing these changes allows us to maintain the quality of the doctor-patient relationship and optimal health care.
XXI century´s Medicine uses all the technological advances taking benefits for the medical act; the best example has been the introduction of Telemedicine.
Bringing technology, computing and digitalization to a purely human relationship is not exempt from risks; it will be necessary to identify them and eliminate the disadvantages that all this may mean as an element contrary to humanity that must always characterize the medical act and health care.
Objectives of Medicine science-and-art must become one in the use of Telemedicine at each personalized medical act.
Anti-CD19 CAR-T cell theraphy in pediatric patients with relapsed/refractory acute lymphoblastic leukemia. Experience at Hospital Infantil Universitario Niño Jesús
Authors: Vergara B. , Herrero B. , Madero L.
Published: September 2021

Acute lymphoblastic leukemia (ALL) continues to be the most frequent neoplasm in childhood, with a 5-year survival rate ranging from 78 to 91%. The increase in the survival rate in the last 40 years has been 30 to 80%, with no comparable improvement in the case of relapsed or refractory ALL. It is for this very reason that there is currently research into innovative treatments, such as CAR-T cell therapy. This treatment involves the ex vivo genetic modification of the patient’s own T cells, enhancing their specificity and cytotoxicity against antigens present in the majority of blasts, such as CD19. In clinical trials carried out worldwide, positive results have been obtained in patients with refractory or relapsed ALL treated with CAR-T 19 therapy, with disease-free survival at one year in up to 50% of patients, and overall survival at one year of 76%. The first published report in Spain with respect to this treatment reproduces the results obtained in clinical trials. The results were reported in HNJS in 2020 involving 8 patients treated with CAR-T 19. Complete remission was observed in 87.5% of patients one month after infusion followed by an overall survival of 75% at the time of analysis (7.6 months mean follow-up duration across all the patients). To date, the most frequent side effects described with the use of this therapy in the short term are cytokine release syndrome and neurotoxicity. This innovative therapy, therefore, represents a paradigm shift in the survival of pediatric patients with relapsed or refractory ALL. Further studies and evidence of its effectiveness and the long-term follow-up of patients treated with this therapy are still needed, but the results to date are encouraging.
GASTRIC OUTLET OBSTRUCTION POST ACID INGESTION IN PEDIATRICS
Authors: Nasr Burkan
Published: September 2021

Aim: Evaluate clinical pattern, diagnosis, surgical management and outcome of Gastric outlet obstruction in children post accidental ingestion corrosive (sulfuric acid of battery) , also role  of continuing public education to reduce and avoid  incidence these unfortunate events.
Patients & method: prospective study for 20 patients’ children with isolated gastric outlet obstruction post corrosive sulfuric acid ingestion was admitted and operated in Saudi hospital at Hajjah Yemen in period April 2015_April 2021.
 The study evaluates patients’ demographic data, clinical presentation, diagnosis and management, also included in this study the Comparison proportions between two surgical procedures used for management this patient (group (A) pyloric resection and gastroduodenostomy and group (B) gastrojejunostomy with Braun anastomosis) with P value >0.05 was non-significant.
Results: Twenty patients with gastric outlet obstruction (12 boys and 8 girls), (Mean age was 4.5). Main presenting symptom recurrent attacks vomiting and loss of weight. The interval between acid ingestion and presentation ranged from 3_4weeks(mean=3.5weeks). The History, Barium swallow and meal used as diagnostic tool because safe, inexpensive. Surgical procedure included group (A)pyloric resection and gastroduodenostomy (n=10) and group (B) gastrojejunostomy with Braun anastomosis (n=10). Comparison between the two surgical procedures show all safe, less morbid, no mortality and no significant difference in end outcome result follow-up period up 2 years, all patients are symptoms free and gained adequate weight.
Conclusion:  for patients children post corrosive accident ingestion with gastric outlet obstruction The History, barium swallow and meal used as diagnostic tool. Early surgery between 4_6 weeks by resection or bypass remains the treatment of choice with best result. To prevent these unfortunate events by encourage the Family education about clear labelling of dangerous substances and keeps this substance Far from reaching the kids.
Key word: corrosive induce gastric outlet obstruction; pyloric stricture; gastric outlet obstruction in pediatrics
REVIEWING THE THERAPEUTIC COMBINATION OF MULTIVITAMINS
Authors: Kwatra Bharat , Rumao Chelsea , Layanal Sherin , Pillai Vaishnav
Published: September 2021

Vitamins are micronutrients which form an essential part of our diet. They are needed for healthy functioning of metabolic activities, some forms of vitamin form basis for our immunity and bone building. Usually essential nutrients cannot be synthesised in our bodies, hence we need to obtain them from our diet. Many Vitamin groups have been studied extensively for the pharmacological effects. Many studies have proved the effectiveness of combination therapies of vitamins with other medication for treatment of various diseases. This review presents all the studies conducted to prove the therapeutic effects of vitamins.

Keywords: Multivitamins, Vitamin A, Vitamin B, Vitamin C, Vitamin D, Ginseng, Niacinamide, Antibiotics, Cefuroxime, DAV Therapy.
REVIEWING THE THERAPEUTIC ACTIVITY OF VITAMIN D WITH ASTAXANTHIN
Authors: Singh Prerna P. , Basu Sneha , P. Sreelakshmi M
Published: September 2021

This article is an examination of the Rar The scientific development and subsequent “vitamin D and astaxanthin” continues to influence the researchers all over the globe today. This article examines the research done and published by researchers and scientists. Consideration of current trends and data in scientific queries and demonstrates further aspects of Therapeutic activity of vitamin D with astaxanthin. Additionally, this article explores options for vitamin D with asthaxanthin in orthopaedic. The combination of both result in  enhanced endurance and walking distance in senior adults, as well as increased muscular strength and size (sarcopenia). Thus, in elderly adults, mobility, endurance, and strength were all increased using a single training strategy. Vitamin D with astaxanthin in ENT. The vitamin D and astaxanthin has been proven to possess effective activity against reactive oxygen species, cell apoptosis, inflammatory and auto immune disorders. Vitamin D with astaxanthin in gynecology.Antioxidants and vitamin D have been found to play an important role in reducing the causes of diseases linked with female infertility.

Keywords: Infertility, antioxidant, otolaryngological diseases, musculoskeletal system, cartilage homeostasis
A História da Cirurgia Plástica no INCA
Authors: Kogut José , Leal Paulo Roberto de Albuquerque , Guimarães Darcy da Silva
Published: September 2021

De forma cronológica, o artigo retrata a História da Cirurgia Plástica no INCA.
Diferenciação Celular: Importância na Hepatocarcinogênese e Papel Modulador do ß-Caroteno
Authors: Naves Maria Margareth Veloso , Moreno Fernando Salvador
Published: September 2021

Esta revisão focaliza a relação entre a diferenciação das células ovais e a origem celular do câncer hepático, bem como os estudos recentes sobre a ação do ß-caroteno na diferenciação celular. As denominadas células ovais, que proliferam durante as etapas iniciais da hepatocarcinogênese, são células progenitoras bipotentes que podem se diferenciar em hepatócitos e em células epiteliais biliares, conforme demonstrado em modelos in vivo de diferenciação celular hepática. Postula-se que o câncer hepático originar-se-ia das células ovais, por bloqueio irreversível do processo de diferenciação, resultante da ação de hepatocarcinógenos. Desse modo, seriam geradas células imaturas transformadas que deteriam potencial proliferativo e imortalidade, em contraposição à teoria de que o câncer desenvolverse- ia a partir da “desdiferenciação” dos hepatócitos. Descreve-se que o ß-caroteno (e outros carotenóides sem atividade pró-vitamínica A) é capaz de induzir a diferenciação celular, em modelos in vitro. Além disso, foi observado, in vivo, que o carotenóide reduziu o número de células ovais remanescentes (ao final do período experimental), tanto em modelo de hepatocarcinogênese química quanto de diferenciação celular hepática. Estes achados sugerem que o ß-caroteno pode favorecer a diferenciação terminal completa das células ovais, com implicações na quimioprevenção do câncer hepático.
A Imagem Corporal Alterada do Laringectomizado: Resignação com a Condição
Authors: Pedrolo Flávia Tatiana , Zago Márcia Maria Fontão
Published: September 2021

Com a finalidade de adequar a assistência ao laringectomizado, este estudo tem o objetivo de identificar as dimensões da alteração da sua imagem corporal. Trata-se de um estudo exploratório realizado com 9 laringectomizados, no qual a coleta de dados ocorreu com base na entrevista semi-estruturada. Na análise dos dados foram identificadas duas categorias analíticas: reconhecimento e enfrentamento da imagem corporal alterada. Essas categorias foram integradas no tema “resignação com a imagem corporal alterada”, que revela as dimensões como um processo de resistência ao ideal de imagem corporal. Como tal, reflete uma condição de sofrimento e desafios que requerem intervenção da equipe de saúde.
Receptores Hormonais: Associação com Fatores Prognósticos para Câncer de Mama
Authors: Eisenberg Ana Lucia Amaral , Koifman Sergio , Rezende Lidia Maria Magalhães Cordeiro de
Published: September 2021

Os tumores de mama positivos para receptores de estrogênio (RE) e/ou de progesterona (RP), além de apresentarem um prognóstico mais favorável, mostram associações com outras variáveis de bom prognóstico. A partir de um estudo com 306 carcinomas ductais infiltrantes de mama, foram construidos modelos preditivos para a positividade dos RE e dos RP. Foram estudadas variáveis relacionadas às pacientes e ao tumor (características macro e microscópicas e marcadores tumorais processados por imuno-histoquímica). Na análise bivariada, algumas variáveis se associaram estatisticamente com a positividade dos RE e RP, porém, na regressâo logística não condicional somente as seguintes variáveis foram fatores preditivos independentes: idade da paciente (RE e RP), idade da menarca (RP), grau histológico (RE e RP), RP (RE) e p53 (RE). De acordo com os resultados deste estudo as variáveis idade da paciente ao diagnóstico, grau histológico, RP e p53 foram fatores preditivos para a positividade dos RE, enquanto que a idade da paciente, a idade da menarca e o grau histológico o foram para os RP.
Câncer Gástrico em Minas Gerais: Estudo sobre o Perfil da Morbimortalidade Hospitalar
Authors: Siman Juliana Barros , Oliveira Júnior Pedro Paulo Lopes de , Simões Milena de Oliveira , Boone Dayany Leonel , Freitas Eulilian Dias de , Gomes Ana Luiza Drumond , Gomes Rafael Henrique Neves , Clarindo Ana Paula Pessotti , Alves Waneska Alexandra
Published: September 2021

Introdução: A neoplasia maligna do estômago é o quinto tipo mais incidente de neoplasia e a terceira principal causa de morte por câncer no mundo. É uma patologia grave, geralmente diagnosticada em estágios avançados no Brasil. Objetivo: Analisar, por meio dos registros no Sistema de Informações Hospitalares do Sistema Único de Saúde (SIH-SUS), o perfil das internações por neoplasia maligna do estômago em hospitais conveniados aos setores público e privado no Estado de Minas Gerais de 2007 a 2017. Método: Estudo descritivo, quantitativo, observacional, com dados públicos retrospectivos do SIH-SUS, no período de 1 de janeiro de 2007 a 31 de dezembro de 2017. Os locais de estudo foram as unidades hospitalares que integram o SUS (públicas ou particulares conveniadas). Resultados: Houve semelhança quanto à realidade nacional na maioria dos aspectos analisados, como aumento na taxa de internações e redução das taxas de letalidade hospitalares no decorrer dos anos. A maioria dos atendimentos foi de urgência e em regime privado. O sexo masculino (67,3%) e a faixa etária de pessoas com 60 anos ou mais (60,7%) obtiveram maior incidência. O tempo médio de internação foi 1,4 vezes maior no regime público do que no privado; a letalidade hospitalar foi maior no serviço público (8,9%) em relação ao privado (4,9%) nos atendimentos eletivos. Conclusão: A distribuição dos resultados foi heterogênea entre as Macrorregiões de Saúde, demonstrando que a descentralização de recursos ainda é um grande desafio do sistema de saúde brasileiro.
Salivary Gland Tumors: a Ten-Year Retrospective Analysis in a Brazilian Teaching Hospital
Authors: Ribeiro Alice , Carvalho Ana Luisa Saraiva Homem de , Koth Valesca Sander , Campos Maria Martha
Published: September 2021

Introduction: The tumors affecting salivary glands have a wide morphological diversity. Objective: This study aimed to examine the prevalence of salivary gland tumors in patients treated at São Lucas Teaching Hospital at the Pontifical Catholic University of Rio Grande do Sul (HSL-PUCRS), in Porto Alegre (RS), Brazil, from 2007 to 2016. Method: A retrospective study analyzing 201 files from the Department of Pathology at the HSL-PUCRS was carried out, by revising the medical records. Results: Seventy-three cases of salivary gland tumors were found, and their electronic and physical medical records were analyzed. Of the 73 cases, 56 (76.7%) were benign tumors and 17 (23.3%) were malignant tumors. The age group with the highest number of cases was between 41 and 60 years of age and the highest prevalence was found in females, with 54.8% of the cases. The parotid gland presented the highest prevalence, accounting for 72.6% of the cases. The predominant neoplasia was the pleomorphic adenoma, accounting for 53.4% of the tumors. The standard of distribution of neoplasms of salivary glands was similar to the encountered in other Brazilian regions. Conclusion: The largest salivary glands were the most affected by neoplastic processes. Pleomorphic adenoma and adenoid cystic carcinoma were the most frequent benign and malignant tumors, respectively, and parotid gland was the most affected site. In the light of previous literature data, the results allow to infer that some demographic characteristics (for example, sex and age) vary among the different geographic regions.
Funciones del Coordinador de las Comisiones Técnicas del Consejo Nacional de Acreditación en Informática y Computación A.C. (CONAIC)
Authors: Aldrette Malacara A. , Garcés Báez A.
Published: September 2021

Es importante reflexionar sobre el perfil deseable y las funciones del Coordinador de la Comisión Técnica (CT) debido a que es una figura relevante para que la CT se desempeñe con éxito en el marco del Manual para el proceso de acreditación del Consejo Nacional de Acreditación en Informática A. C. (CONAIC). Se realiza la presente propuesta con respecto al perfil que debe cubrir el Coordinador de la CT (CCT) y sus funciones específicas, dichos elementos son de suma utilidad y pueden ser considerados para la toma de decisiones por el Comité de Acreditación y para la interacción enriquecedora de los miembros de la CT, respectivamente. Se presentan elementos útiles para todos los involucrados durante el proceso de acreditación de un programa educativo, en las etapas previa, durante y posterior a la visita de la institución correspondiente.

It is important to think over on the desired profile and functions of the Coordinator of the Technical Committee (TC) because it is a relevant performer for the CT success under the Manual for the accreditation of the National Accreditation Council in Computers AC (CONAIC). This is a proposal with respect to the profile that should cover the Coordinator of the CT (CCT) and their specific functions are performed, these elements are very useful and can be considered for decision making by the Accreditation Committee and for enriching interaction members of the CT, respectively. Useful elements for all involved are presented during the process of accreditation of an educational program, in the previous stages, during and after the visit to the institution.