bluuebunny/crossref_metadata_2025 huggingface dataset:
Squamous Cell Skin Cancer Treatment Experience in Patients with Dystrophic Form of Epidermolysis Bullosa
Authors:   BELA. Children-Butterflies’ Charitable Foundation, Moscow, Zinovyev G.V. , Drozdovskaya D.A. , Anokhina Ye.M. , Gekht M.A. , Pleshkov A.S. , Sabitova A.A. , Kornev V.I. , Nikiforov M.V. ,   N.N. Petrov National Medical Research Center of Oncology, Saint-Petersburg,   R.M. Gorbachyova Research Institute of Pediatric Oncology, Hematology and Transplantology of the Academician I.P. Pavlov First Saint-Petersburg State Medical University,   Saint-Petersburg State University, N.I. Pirogov High Medical Technology Clinic of Saint-Petersburg State University,   A.M. Nikiforov All-Russian Center of Emergency and Radiation Medicine, Saint-Petersburg
Published: May 2024

Epidermolysis bullosa (EB) is a hereditary, heterogeneous group of rare genetic dermatoses characterized by the skin and mucous membranes fragility. One of the most severe forms of the disease is dystrophic EB, the severity of which is due to the generalized nature of the lesion of the skin and mucous membranes of internal organs. In the absence of pathogenetic treatment of EB, multidisciplinary care is aimed at minimizing the risk of progression of skin lesions, relieving symptoms and specific complications. One of the most dangerous complications of EB is the early development of squamous cell skin cancer (SCC), which is especially characteristic for patients with dystrophic form. There are no generally accepted recommendations for the systemic therapy of SCC in EB, as well as clear evidence of the cytotoxic drugs clinical effectiveness in the treatment of this group of patients. The presented in the article experience of treatment of both localized and widespread forms of SCC in patients with dystrophic form of EB shows the possibilities of the surgical approach and the systemic therapy effectiveness. Of course, any experience in the treatment of a malignant tumor with such a severe orphan disease is of great value and can help in the selection of the most effective treatment tactics in the future.
Immunotherapy in Combination with Radiation Therapy in the Treatment of Patients with Squamous Cell Skin Cancer
Authors:   N.I. Pirogov Russian National Research Medical University, Kravchuk D.A. , Trofimova O.P. , Ivanilov K.Yu. , Nazarova V.V. , Demidov L.V. , Orlova K.V. ,   N.N. Blokhin National Medical Research Centre of Oncology,   Russian Medical Academy of Continuous Professional Education
Published: May 2024

Squamous cell skin cancer (SCC) is the second most common malignant neoplasm. The incidence of SCC continues to grow. As a rule, the tumor is characterized by a benign clinical course and is cured surgically, but in some cases, the development of locally common (and/or metastatic) forms is observed. For a long period of time, there were no methods of drug therapy of patients with such forms of SCC that would lead not only to a local effect, but also to an increase in life expectancy. In most cases, SCC is characterized by a high mutational load, the presence of PD-L1 expression, which potentially suggests a possible sensitivity of the tumor to immunotherapy. This knowledge contributed to the conduct of clinical studies of anti-PD-1 immunotherapy in locally common inoperable and/or metastatic forms of SCC. In the USA, in 2018, the first drug for the treatment of patients with locally advanced inoperable and/or metastatic form of SCC, cemiplimab, was approved for the first time. In 2020 another anti-PD-1 drug, pembrolizumab, was approved, which allowed expanding the possibilities of drug therapy for this category of patients. Despite the high frequency of objective responses against the background of anti-PD-1 immunotherapy in the first line (about 50%), a number of patients have stabilization of the disease or progression of the process. Stabilization of the disease is not enough for most patients, taking into account the peculiarities of clinical manifestations characteristic of SCC, which requires the search for new approaches and the use of immunotherapy with other treatment options to improve immediate and long-term results. The article presents a clinical case of a patient with locally advanced right shin SCC who received anti-PD-1 immunotherapy (nivolumab) in combination with radiation therapy as part of first-line therapy. On the background of such therapy, it was possible to achieve some success.
The Role of Immunosuppressive Factors in the Prognosis of Cellular Therapy Efficacy in Patients with Solid Tumors
Authors:   N.N. Petrov National Medical Research Centre of Oncology, St. Petersburg, Danilova A.B. , Novik A.V. , Nekhaeva T.L. , Baldueva I.A. ,   St. Petersburg State Pediatric Medical University
Published: May 2024

Production of different factors with wide immunosuppressive properties by tumor cells is one of the mechanisms that support tumor growth. We think that immunosuppressive action of tumor cells should be taken into account for cellular antitumor therapy optimization. Aim of the study – to evaluate the effectiveness of cellular immunotherapy factors (ISF) for response prediction in patients receiving tag7/PGRP-S gene modified tumor cells (GMV) or autologous dendritic cells vaccine (DCV) for melanoma (Mel), kidney cancer (RCC) and soft tissue sarcoma (STS). Material and methods. We have treated 204 patients with cellular therapy since 2001 till 2016 (88 – GMV, 1 16 – DCV). ISF (MICA, TGF-β, IL-10 и VEGF) were measured in tumor tissue cultures of 88 patients (71 – Mel, 6 – RCC, 11 – STS). Median age of patients was 51 year. Patient were divided as having insufficient response (IR) or sufficient response (SR) for the analysis purpose. Results. ISF concentration in cultures of patients with IR was higher than in patients with SR (р < 0.05). SR could be predicted correctly in 74.4% using ISF. The most important factor was TGF-β1. In the Cox model TGF-β1 and MICA levels were significant predictors of overall survival for Mel patients (р < 0.05). VEGF was the most important factor for time to progression prognosis. Spirman correlations showed moderate significant correlation between ISF (р < 0.05). Conclusions. ISF concentration in cell cultures obtained from the patients with Mel, RCC or STS is important independent predictive factor for time to progression and overall survival. Our data supports rigid selection criteria based on biological properties of tumor cells for patients receiving cellular therapy for solid tumors
Study of the Role of Professional Factors in the Occurrence of Neoplasms in Employees of Port Enterprises of Novorossiysk
Authors:   Kuban State Medical University, Leonov M.G. ,   Novorossiysk State Maritime University named after Admiral F.F. Ushakov,   Novorossiysk Oncological Dispensary No. 3,   Novorossiysk Clinical Center of the Federal Medical and Biological Agency, Kharbandaridi E.S. , Rakhuba G.A. , Istomina D.E. , Chernov S.N.
Published: May 2024

According to the scientific literature, when studying the health status of workers engaged in various activities at port enterprises, it was revealed that they have a high risk of diseases of the visual organs, pathology of the ent organs and the endocrine system. A number of researchers believe that working at the port is a factor that increases the risk of diseases of the urinary system. According to other data, port work increases the risk of cardiovascular diseases. Many authors have presented results confirming the negative impact of professional activity in the port on human health, which increases the risk of developing such chronic non-communicable diseases as diabetes mellitus and malignant neoplasms. The increase in cancer incidence remains a problem worldwide, and advances in diagnosis and treatment do not lead to a significant reduction in morbidity and mortality. Undoubtedly, the priority reasons determining the growth of oncological morbidity of the population are various environmental factors, including occupational harmfulness.
Modern Ideas About Diffuse Alopecia
Authors:   Selfmade Clinic, Krasnodar, Ereshko A.R.
Published: May 2024

This article presents modern ideas about the etiology and pathogenesis of diffuse alopecia. The classification, possible etiological factors, and links of pathogenesis are analyzed in detail. All possible approaches to the reatment of diffuse alopecia are described, including external therapy and physiotherapy techniques.
Modern Approaches to the Treatment of Periorbital Veins
Authors:   Artve Clinic, Moscow, Popova A.S.
Published: May 2024

This article presents modern approaches to the treatment of periorbital veins. The current methods of periorbital vein removal, such as sclerotherapy, phlebectomy, and laser removal, are described. The advantages and disadvantages of the above-mentioned techniques and therapeutic advantages are described.
Morphofunctional Characteristic of the Hepar and Pancreas When Exposed to the Hepatoprotector Remaxol in Cases of Acute Alcohol Damage in Rats
Authors:   Izhevsk State Medical Academy, Styazhkina S.N. , Glushkova T.G. , Kir'yanov N.A. , Zaitsev D.V. , Lentsova S.I. , Gorbunova M.A.
Published: May 2024

Purpose of the study. To study the effect of hepatoprotective drug Remaxol on morphology of the liver and pancreas as well as on biochemical indices of blood serum in rats with alcohol damage. Material and methods. The study was carried out on sexually mature male white laboratory rats divided into three groups: 1st control group – intact animals (2 rats); 2nd – experimental animals (5 rats), on which acute pancreatitis on the background of alcohol poisoning was modeled by daily administration of 40% aqueous ethanol solution at a dose of 5 mg/kg weight for 7 days without treatment; 3rd – experimental group (5 rats) with alcohol exposure and with administration of Remaxol at a dose of 5 mg/kg weight daily for another 7 days. Morphological study of the liver, its macrostructure was carried out, diameters of hepatocytes and pancreatic acinuses in animals of experimental and control groups were measured, biochemical parameters were estimated. Results. Blood tests indicate acute alcohol poisoning in the experimental groups; short-term (7 days) alcohol damage has less effect on the size of hepatocytes than on the size of pancreatic acini; pancreatic acini were more reactive to the toxic effect of alcohol; against the background of insignificant morphometric differences, the morphological signs of cells and organs changed; in the liver and pancreas there were signs of inflammatory (swelling of cells in the liver and pancreas). Conclusion. Histological picture of the liver and pancreas of animals with acute alcohol damage against the background of Remaxol treatment showed a decrease in the toxic effect of 40% alcohol on hepatocytes and pancreatocytes, normalization of their morphological parameters.
Telemedicine Technologies in Hepatology: Time to Move Forward?
Authors:   United Medical Systems, Moscow, Gonik M.I. , Bogomolov P.O. , Bueverov A.O. ,   Moscow Regional Research Clinical Institute named after M.F. Vladimirsky,   Ministry of Health of the Moscow Region, Krasnogorsk,   Russian University of Medicine, Moscow, Shub N.A. , Sapanyuk A.I. , Ushkanenko I.N. , Maev I.V.
Published: May 2024

The article considers the possibility of using telemedicine technologies in providing specialized medical care to patients with chronic hepatitis C and nonalcoholic fatty liver disease. Foreign experience of implementation of this direction of work and our own results are presented.
Análisis del crecimiento de Trifolium repens cultivado en pasivos mineros artificialmente como estrategia de remediación
Authors: Yaulilahua-Huacho Russbelt , Huere-Peña Jorge Luis , Sumarriva-Bustinza Liliana Asunción , Castañeda-Campos Cesar , Martínez-Cáceres Manuel Agustín
Published: May 2024

Los pasivos ambientales mineros generan la degradación del suelo a la contaminación agua; por ello, que el uso de materia orgánica y humus como estimulantes y plantas con elevada producción de biomasa que a través de sus raíces hagan la extracción de contaminantes. De ahí que el objetivo fue evaluar la germinación y crecimiento del pasto trébol blanco (Trifolium repens) en pasivos mineros, con la adición de tierra negra y compost como sustratos. El estudio se realizó en la Compañía Buenaventura Julcani Huancavelica Los tratamientos estudiados fueron: T1 (relave puro), T2 (relave puro y tierra negra), T3 (relave puro y compost), T4 (relave puro, tierra negra y compost) en combinaciones de 4: 3,1: 3,1: 3:1,1 con total de doce unidades experimentales. Se utilizó un diseño completamente al azar (DCA) con arreglo factorial 1 x 4, considerando en cada tratamiento doce repeticiones. Los resultados, en germinación de semillas de Trifolium repens a los 18 días, se obtuvo un porcentaje de germinación del 31 ± 7 en el tratamiento uno de relave puro (grupo control), el 55 ± 10 en tratamiento dos de relave puro y tierra negra, el 26 ± 10 en tratamiento tres de relave puro y compost, y el 41 ± 9 en el tratamiento cuatro de relave puro, tierra negra y compost, para las semillas de Trifolium repens. La combinación de relave puro, tierra negra y compost mejora la germinación en comparación con el grupo control y el tratamiento tres, pero no alcanza la efectividad del tratamiento dos.
Gestionar el Efecto de fertilizantes NPK y dos densidades de siembra en maíz (Zea mays L.)
Authors: López Córdova Jenny Jeanette , Piñarreta Olivares Rony Alexander , García Juárez Hugo Daniel , Nole Zapata Jersson Anthony , Rodríguez Abraham Antonio Rafael
Published: May 2024

El maíz, un cultivo ampliamente consumido a nivel mundial, es una valiosa fuente de carbohidratos, proteínas y nutrientes esenciales. Esta investigación se centró en analizar el impacto de tres dosis de fertilizantes NPK en dos densidades de siembra de maíz (Zea mays L.) en Piura, Perú. El estudio se llevó a cabo con un diseño experimental de bloques completos al azar, combinando tres dosis de NPK y dos densidades de siembra, totalizando 24 parcelas. Se evaluaron el rendimiento, longitud, diámetro y peso de las mazorcas, así como el índice de cosecha. Los resultados destacan que la combinación de una densidad de siembra de 75 000 plantas por hectárea con la dosis D3 de fertilizante NPK (200-80-100) logró el mayor rendimiento de 16,399 kg/ha-1, evidenciando diferencias significativas en comparación con otras combinaciones. Estos hallazgos subrayan la relevancia de la densidad de siembra y las dosis de fertilizantes NPK en la productividad del maíz, resaltando la importancia de estos factores en la optimización de los rendimientos agrícolas.
Sentences denoting the elimination of the result of an action as a semantic-structural type
Authors:   Lomonosov Moscow State University, Mukhacheva I. V.
Published: May 2024

The article is devoted to Russian sentences denoting the elimination of the result of the previous action. Their semantic and syntactic structures are analyzed in order to understand whether such sentences constitutea united semantic-structural type. The analysis shows that these sentences have a similar propositional structure. They include a proposition-macrosituation which consists of three situations: the liquidated situation; situation-action aimed at eliminating the result of the previous action and new situation. The sentences have a similar semantic structure in general, but they differ from each other in more particular semantic aspects. There are two subtypes among them. The first subtype denotes the elimination of contact. The sentences of this subtype have three obligatory actants – Subject, Object 1 and Object 2. The second subtype denotes changing the shape of an object. The sentences of this subtype have two obligatory actants – Subject and Object. In spite of semantic differences, syntactically sentences denoting the elimination of the result of an action are built according to the general model: ‘Subject + predicate with the meaning of eliminating the result of an action + Object’. This general model isrealized in two particular models for each sentence subtype. Sentences denote the elimination of contact are constructed according to the model ‘Subject + predicate of the elimination of contact + Object 1 and / or Object 2’: Mama razdvinula zanaveski(‘M om parted the curtains’); Soldat razobral pulemet(‘The soldier dismantled the machine gun’); Rabochie razgruzili mashinu(‘The workers unloaded the car’). Sentences denote changing of the shape of an object are built according to the model ‘Subject + predicate of changing shape + Object’: Mama razvernula nebrezhno skatannyi kover(‘Mom unrolled a carelessly rolled carpet’).
Agrammatical texts and their place among the of speech activity’s products
Authors: Norman B. Ju.
Published: May 2024

Agrammatism in Russian language is understood as the production of an utterance with such violation of morphological and syntactic norms, by which the main means of expressing grammatical meanings are word order and (in oral speech) intonation. Government and coordination are supplanted by parataxis, the frequency of the use of the nominative case increases. This is a situation when there are no proper means of connection between words in an utterance (inflectional morphemes, prepositions, conjunctions, particles), and the utterance itself becomes “crumbly”. The factual material for the paper is extracted from three communication areas: colloquial speech, special texts (commercial and technical advertising) and fiction. It is shown that there are general linguistic grounds that explain the development of this phenomenon. These are: a) expectation on the lexical semantics of words and the combinatorial connections inherent in them; b) grammatical semantics, represented by the linear order of words (and in oral speech – by intonation also); c) support from social conditions, personal characteristics of those who communicate, everyday context, paralinguistic means. The special functional and stylistic role of names in the syntax of the phrase is noted – in their opposition to the verb. In the facts of agrammatism, the interaction of language means with each other is manifested. In this regard, particular prerequisites and conditions are systematized that contribute to the emergence of agrammatic constructions in the Russian language – such as lemmatization, compression, ellipsis, the use of loan-words, etc. A general conclusion is made that agrammatism is not so much a fact of text destruction, but situational (discursive) conditional use of the diverse functionality of the language.
Evaluative statements in the comments to stream
Authors:   Yaroslav-the-Wise Novgorod State University, Shmeleva T. V.
Published: May 2024

The article discusses the semantic type of Russian sentences as it is presented in the comments to a livestream – a video broadcast of communication of a host-streamer with their viewers on some topic, in the chosen case – a musical one, involving a performance of cover versions of popular songs in different styles by the streamer. Based on the concepts of constructive, semantic and actual syntax, as well as taking into account the discursive conditions for the functioning of the analyzed evaluative statements, a range of simple sentence models used to construct them, ways to designate all elements of the evaluation situation – the subject of evaluation, its object, the evaluation itself, mechanisms of model distribution and expression of evaluation within the model or its dissemination. The main attention is paid to expressing the meaning of evaluation, the variety of means of which creates paradigmatic series of sentences with homogeneous evaluative vocabulary. It was revealed that the composition of the evaluative predicate vocabulary includes both literary and slang, while its grammatical possibilities – inflectional and derivational – are realized to the maximum. It is shown that for the considered discursive conditions, when implementing evaluative statements, the meaning of a high level of evaluation intensity is actualized, which is ensured by a series of techniques, including the inclusion of a special type of adjective and substantive forms (elatives, augmentatives), constructions with particles, pronouns, and going beyond a simple sentence into the realm of parataxis. The results of the study clarify ideas about the grammar of evaluativeness in its media implementation, and also convince us that the appeal to the discursive conditions for the implementation of different semantic types of sentences opens up new aspects of their functioning,in particular, the specifics of the constructive and semantic aspects.
EPİDEMİYOLOJİDE MATEMATİK MODEL KULLANIMI: GELECEK TAHMİNİ
Authors: Hayran Osman , Balcı Yapalak Ayşe Nur
Published: May 2024

İnsan bedenine ilişkin “normal” işlevleri tanımlama ihtiyacının ortaya çıktığı günden beri sayıları kullanarak değerlendirme yapmak alışkanlık ve gereklilik haline gelmiştir ki sayı matematiğin dilidir. Yirminci yüzyılda bilgisayarların kullanılmaya başlanması ile yeni bir aşamaya geçilmiş ve hastalıkların tanısı, tedavisi, izlenmesi ve ileriye yönelik beklentilerin belirlenmesi konusunda önemli adımlar atılmıştır. Günümüzde veri madenciliği, yapay zeka, makine öğrenmesi, nöral ağ uygulamaları tıbbın her alanına girmiş ve geliştirilen algoritmalarla, modellemelerle matematik kullanımı tıbbın ve sağlık hizmetlerinin vazgeçilmez bir parçası haline gelmiştir. Özellikle son yaşanılan COVID-19 pandemisi döneminde matematik modellemelere olan ihtiyacın önemi daha da belirginleşmiştir.Sağlıkla ilgili her türlü durum ve olayın sıklığını ve dağılımını inceleyerek uygun kontrol yöntemleri geliştirmeyi amaç edinmiş epidemiyoloji bilimi için önemli bir alan olan matematik modellemeler başlangıçta sihirli bir formül gibi görünse de pek çok açmaz ile karşı karşıya olunduğu görülmektedir. Bu çalışmada tıpta matematik modellemelerin kullanılma amaçları ve türleri konusunda özet bilgi verildikten sonra epidemiyolojik amaçla geliştirilmiş olan çeşitli modellemeler üzerinde durulmuştur.
FİYAT HAREKETLİLİKLERİ BAĞLAMINDA MEMLÛK DEVLETİ’NDE EKONOMİK BUHRAN (1511-1517)
Authors: Erzurumlu Harun
Published: May 2024

Memlûk Devleti’nin genel olarak gelir kaynağı tarım ve ticarettir. Bu iki olguya etki eden olumlu veya olumsuz her türlü unsur, Memlûk ekonomisini etkilemiştir. 1511-1517 tarihleri arasında Memlûklerin tarım ve ticaretinin en yoğun zarar gördüğü dönemler olmuştur. Portekizlilerin dünya ticaret güzergâhlarının değişmesinde üstlendikleri rol, Memlûk ticaretini kesintiye uğratırken; ülkede bir türlü sonu gelmeyen salgın hastalıklar ise tarımsal faaliyetleri sekteye uğratarak ülke ekonomisine ağır darbeler vurmuştur. Bu olumsuz durumlar, doğal olarak ülke içinde bir türlü önü alınamayan fiyat hareketliliklerine neden olmuştur. Yöneticilerin piyasayı normalleştirmek amacıyla yaptıkları müdahaleler, piyasada ters tepki yaratarak fiyat hareketliliklerini daha da artırmıştır. Bu çalışmada, Osmanlıların Memlûk ülkesini ele geçirmeden hemen önce Memlûk Devleti’nin içinde bulunduğu ekonomik buhranı, ülkede meydana gelen fiyat hareketlilikleri üzerinden açıklanmaya çalışılmıştır. Bu yönüyle genellikle siyasi boyutu öne çıkan bu dönemin iktisadi yönüne de vurgu yapılmıştır. 1511-1517 yıllarında meydana gelen olaylar kronolojik olarak anlatılırken, çalışmanın sonunda bazı ürünlerin fiyat hareketliliklerini gösteren grafikler okuyucunun istifadesine sunulmuştur.
Estrategia metodológica para atención de estudiantes con necesidades educativas especiales no asociadas a la discapacidad en sector rural de Ecuador
Authors: Rivadeneira-González Edgar , Fernández-Fernández María
Published: May 2024

The article aims to present the design of a methodological strategy for the care of students with special educational needs not associated with disabilities in the rural sector of the city of Manta, at the Ahitana Ponce Santana Fiscal Educational Unit. The methodology was mixed approach, with a descriptive scope and a non-experimental design. The methods used were analysis, synthesis, inductive and deductive reasoning; additionally, interviews and surveys were conducted with a sample of 3 teachers and 84 students corresponding to sections A and B of the 8th year of Basic General Education, respectively. According to the teachers, the main special educational needs not associated with disabilities in the students include learning difficulties, attention deficit and hyperactivity disorder (ADHD), and language or communication disorders. Students show difficulties in understanding and applying concepts, insecurities in self-esteem and academic confidence, as well as difficulties in conflict resolution and decision-making. Therefore, additional support is required, as well as the development of specific strategies to improve the learning process and academic well-being. The conclusion is reached through a methodological strategy that includes activities aimed at initial assessment, design of individualized intervention plans, use of technological resources to enhance learning and attention, teacher training and support, as well as collaboration with families.
Religious Populism and the Future of Indian Democracy
Authors: Editors Intersections
Published: May 2024

An article summarizing a special issue of Studies in Indian Politics investigates the contemporary struggle to maintain democracy in the country.
An Unfinished but Hopeful Country
Authors: Editors Intersections
Published: May 2024

An analysis of a film series on equality and faith in post-pandemic Indonesia.
Reinventing How Journalists and Religious Scholars Communicate
Authors: Editors Intersections
Published: May 2024

This article summarizes a 2018 conference at Northeastern University dedicated to investigating the relationship between journalists and religious scholars as it relates to reporting on sensitive issues in religion, politics, and society.
PRECONCEITO? PRESENTE! HOMOFOBIA? PRESENTE! EDUCAÇÃO SEXUAL? FALTOU, PROFESSOR/A
Authors: De Jesus Souza Elaine , Paula da Rocha Eugerbia , Francisca da Silva Elânia
Published: May 2024

Este estudo tem como objetivo problematizar discursos e cenas escolares acerca de práticas homofóbicas na escola, analisando de que modos a Educação Sexual contribui para a (des)construção de preconceitos e discriminações. Trata-se de um recorte de uma pesquisa qualitativa realizada em escolas públicas de dois municípios cearenses, por meio de entrevistas semiestruturadas com docentes e da análise foucaultiana do discurso. Os resultados obtidos evidenciam uma carência na formação docente aliada a um fundamentalismo religioso, que dificultam abordagens socioculturais da Educação Sexual na escola e em consequência a presença marcante da homofobia, que ocorre de forma sutil ou manifesta, por meio de preconceitos e discriminações. Assim, são necessárias (in)formações, articulações entre campos de estudos, comunidades e escola, a problematização de discursos e estratégias didático-metodológicas para o reconhecimento de identidades/diferenças, visando à desconstrução da homofobia na escola.
High aspect ratio SiO2/SiN (ON) stacked layer etching using C3HF5, C4H2F6, and C4H4F6
Authors: Abe C. , Sasaki T. , Kondo Y. , Yoshinaga S. , Kuboi S. , Takahashi Y. , Kato K. , Shimizu H. , Fukumizu H. , Omura M.
Published: May 2024

High aspect ratio SiO2/SiN (ON) stacked layer etching using hydrofluorocarbon gases was conducted with various ratios of H, F, and C to achieve higher etching rates and precise profile control. The experimental gases were C3HF5, C4HF5, C4H2F4, C4H2F6, C4H4F6 and C5H2F10. The oxygen gas flow rate and mixing ratio were optimized to maximize mask selectivity while avoiding clogging at the top of the mask. For comparison, C4F6/CH2F2/Ar/O2, and C4F6/C4F8/CH2F2/Ar/O2 were used as reference gas mixtures. The initial screening narrowed the candidate pool to 3 gases: C3HF5, C4H2F6, and C4H4F6. At equivalent power, the C3HF5 condition achieved a 15% faster ON etch rate, and C4H2F6 achieved a 9% faster ON etch rate compared to the reference condition. Only C4H4F6 showed a worse ON etch rate than the reference (∼33%) due to severe mask clogging. Furthermore, C3HF5 achieved a 29% faster ON etch rate under high power conditions. It also achieved a 57% faster ON etch rate without excessively compromising selectivity or bow CD expansion after optimization. We report detailed comparisons of etch rate and clogging while controlling the CD profile in the ON stack process.
Imagem e corrosão: a écfrase crítica na narrativa de W. G. Sebald
Authors: Cardoso Luis Gustavo
Published: May 2024

Este artigo investiga a écfrase na produção narrativa de W. G. Sebald. Seu corpus está delimitado por uma série de imagens e écfrases selecionadas do romance Os anéis de Saturno, bem como por passagens do primeiro longo poema da obra Nach der Natur: Ein Elementargedicht (“Segundo a Natureza: um poema elementar”), em que narrador trata da vida e obra de Matthias Grünewald. Ao mobilizar a análise e descrição da écfrase, situando-a como recurso retórico e literário de efeito poético e crítico, este artigo desenvolve-se sobre a hipótese de que Sebald se vale da écfrase a fim de restituir a experiência tal como tomada por Walter Benjamin, isto é, como tradução do vivido em experiência viva.
Bipolar Junction Transistor Amplifiers-State-Space-Modeling Across Frequencies
Authors: Campos-Salazar José M. , Aguayo Juan , Rafiezadeh Roya , Garcia-Rojas Gabriel
Published: May 2024

This study presents a comprehensive analysis of three
bipolar-junction-transistor (BJT) amplifier topologies common-emitter,
common-collector, and common-base amplifiers-under transient conditions
across low and high frequencies. Utilizing MATLAB-Simulink simulations,
the response of each amplifier topology to varying frequency inputs is
investigated, with a particular emphasis on state space modeling.
Beginning with low-frequency models characterized by specific voltage or
current sources, the study delves into the steady-state dynamics of
output variables, employing state space equations to elucidate amplifier
behavior. Notably, the common-emitter amplifier topology exhibits high
gains, as corroborated by established literature, underlining its
potential for high-performance applications. Conversely, the
common-collector and common-base amplifier topologies demonstrate lower
gains, reflecting distinct design characteristics. Transitioning to
high-frequency operation, the impact of Miller capacitance on gain
reduction is explored, especially pronounced in the common-emitter
amplifier topology. Despite this, all amplifier configurations remain
functional, with state space models validated through meticulous
simulations. Simulation parameters are meticulously adjusted to
accurately represent real-world scenarios, enhancing the reliability of
the findings. These insights underscore the importance of comprehending
amplifier behavior across different frequency domains, with state space
modeling offering a powerful framework for analysis. By providing
detailed insights into BJT amplifier performance under transient
conditions, this study facilitates informed decisions regarding
amplifier configuration selection and design, tailored to specific
application requirements and frequency considerations.
Non-Puerperal Uterine Inversion Caused by Embryonal Rhabdomyosarcoma in an Adolescent: A Case Report
Authors: Asmouki Hamid , Oumalloul Basma , Essaoudy Ilyass , Sali Myriem , Fakhir Bouchra , Soumani Abderraouf
Published: May 2024

Introduction: Non-puerperal uterine inversion is an uncommon gynecologic emergency that can be triggered by either malignant or, more commonly, benign tumors. Uterine sarcoma, including the rare subtype known as embryonal rhabdomyosarcoma, is among the malignant causes. The management of this condition poses a significant challenge for surgeons. Case Report: A 15-year-old nulliparous and virgin female arrived at the emergency department in hemorrhagic hypovolemic shock, experiencing pelvic discomfort and expelling endometrial tissue through the vagina. She underwent a total abdominal hysterectomy with bilateral oophorectomy, a pathological examination revealed that the uterine inversion was caused by embryonal rhabdomyosarcoma. Subsequently, the patient was referred to an oncologist for chemotherapy. Conclusion: Rapid perioperative diagnosis can be achieved through physical examination and magnetic resonance imaging (MRI), with histopathological examination serving as the definitive diagnostic confirmation tool.
Trigeminal Neuroma: A Case Report and Review of the Literature
Authors: Lemtouni K. , Essofi R. , Slioui B. , Hammoune N. , Atmane M. , Mouhsine A.
Published: May 2024

Trigeminal neuromas are rare tumors arising from the trigeminal nerve, often presenting diagnostic challenges due to their infrequent occurrence and varied clinical manifestations. We present a case report of 52 year-old female patient presenting with right diplopia and progressive facial pain resistant to standard treatment. Early recognition and appropriate management are crucial to prevent complications and improve patient outcomes. This report underscores the importance of considering trigeminal neuromas in the differential diagnosis of facial pain and the pivotal role of imaging modalities in guiding clinical management decisions.
A possível interlocução entre as teorias foucaultianas e o sistema carcerário no Brasil
Authors: Costa Abraão Lincoln Ferreira
Published: May 2024

The present article proposes to investigate the theories of the French philosopher Michel Foucault, especially located in Discipline and Punish and Microphysics of Power, trying to bring them closer to the reality of the penal system, as well as the State and Brazilian civil society. Therefore, the search will be divided as follows: First, explore the Foucauldian term “illegalism”, verifying the conditions of its best suitability in cases of violence against detainees within some prisons in the country. Then, the study intends to succinctly address the phenomenon known as “panopticism” and its manifestation, not simply directed to the prison environment, but also perceiving it in school, hospital, military, religious and other spaces. After analyzing the considerations of illegalism and the Panopticon, it will be possible to substantiate the suspicion of the meaning of “docile bodies”, as modes of political and economic subjection, probably resulting from a classist and consumerist system, whose success would depend on the full effectiveness of its mechanisms.
Digital and Sustainable Built Environment Digest [DS-BED]: First Edition May 2024
Authors: Aigbavboa Clinton
Published: May 2024

– Unlocking Africa’s Construction Potentials: The Revitalization solutions. – Sustainable and Innovative Construction Materials. – Construction Digitalization. Sustainable Human Settlement and Construction Research Centre (SHSCRC) DSI-NRF Research Chair in Sustainable Construction Management and Leadership in the Built Environment Faculty of Engineering and the Built Environment University of Johannesburg
APPLICATION PERSPECTIVES OF HOMOGENEOUSLY DISTRIBUTED DISPERSED SINGLE-WALLED GRAPHENE NANOTUBES IN DENTISTRY
Authors: Сущенко А.В. , Олейник О.И. , Красникова О.П. , Никулин Д.С. , Дробяцкая М.В. , Ростова Л.М.
Published: May 2024

В данной статье рассматриваются перспективы использования гомогенно распределенных диспергированных одностенныхграфеновых нанотрубок в стоматологии. Углеродные нанотрубки обладают множеством уникальных свойств, такими как физическая прочность, химическая стабильность, инертность, биосовместимость, что делает их привлекательными для применения в различных медицинских направлениях и стоматология не является исключением. Авторы статьи исследуют возможности использования графеновых нанотрубок для улучшения свойств средств гигиены полости рта, стоматологических материалов и инструментов. В работе анализируются различные механизмы взаимодействия графеновых нанотрубок с компонентами средств гигиены полости рта, стоматологических материалов и инструментов и их влияние на прочность, износостойкость, антибактериальные свойства и другие характеристики. Особое внимание уделяется исследованию биосовместимости, биоактивности и биодеградации графеновых нанотрубок, что является ключевым фактором для их применения в стоматологии. Авторы статьи обсуждают возможные пути интеграции углеродных нанотрубок в матрицы материалов средств гигиены полости рта, стоматологических материалов и инструментария. Статья представляет собой обзор и анализ современных исследований в области применения графеновых нанотрубок в стоматологии, а также предлагает перспективные направления для дальнейших исследований

This paper discusses the prospects of using homogeneously distributed dispersed single-walled graphene nanotubes in dentistry. Carbon nanotubes have many unique properties, such as physical strength, chemical stability, inertness, biocompatibility, which makes them attractive for use in various medical applications and dentistry is no exception. The authors of the paper explore the possibilities of using graphene nanotubes to improve the properties of oral hygiene products, dental materials and instruments. The paper analyzes various mechanisms of interaction of graphene nanotubes with components of oral hygiene products, dental materials and instruments and their influence on strength, wear resistance, antibacterial properties and other characteristics. Special attention is paid to the study of biocompatibility, bioactivity and biodegradation of graphene nanotubes, which is a key factor for their application in dentistry. The authors of the article discuss possible ways to integrate carbon nanotubes into the material matrices of oral hygiene products, dental materials and instruments. The article presents a review and analysis of current research on the application of graphene nanotubes in dentistry, and suggests promising directions for further research
STUDY OF THE MORPHOLOGICAL FEATURES OF THE MICROSTRUCTURE OF HARD TISSUES OF PREPARED TEETH
Authors: Каверина Е.Ю. , Гордеева Т.А. , Малыхина И.Е. , Кошев К.А. , Акопян К.Н.
Published: May 2024

В связи с тем, что в современной клинической стоматологии все шире применяются адгезивные технологии, особую актуальность приобретают вопросы адекватной подготовки адгезионных поверхностей твердых тканей зуба. Известно, что препарирование ротационным инструментом оказывает повреждающий эффект с нарушением микроструктуры эмали и дентина. При этом важнейшими факторами являются режим охлаждения операционного поля и тип привода ротационного инструмента. С помощью сканирующей электронной микроскопии была изучена микроструктура адгезионной поверхности эмали при ее обработке с различными режимами подачи водно-воздушного спрея и различными типами привода бора. С этой целью был использован сканирующий электронный микроскоп CamScan S4. Сканирование эмали проводилось перпендикулярно ходу пучков эмалевых призм при одинаковом увеличении для всех образцов. Материалом для исследования являлись удаленные зубы. Результаты электронной микроскопии наглядно свидетельствовали, что оптимизация таких параметров как режим подачи водно-воздушного спрея, тип привода ротационного инструмента позволяют решить следующие проблемы при препарировании твердых тканей зуба – перегрев тканей зуба; огрубение рельефа поверхности после препарирования; появление сколов и трещин эмали; изменение качества адгезионной поверхности

Due to the fact that adhesive technologies are increasingly used in modern clinical dentistry, the issues of adequate preparation of adhesive surfaces of hard tooth tissues are becoming particularly relevant. It is known that preparation with a rotary instrument has a damaging effect with a violation of the microstructure of enamel and dentin. In this case, the most important factors are the cooling mode of the operating field and the type of rotary tool drive. Using scanning electron microscopy, the microstructure of the adhesive surface of the enamel was studied during its processing with various modes of water-air spray supply and various types of boron drive. For this purpose, the CamScan S4 scanning electron microscope was used. The enamel was scanned perpendicular to the course of the enamel prism beams at the same magnification for all samples. The material for the study was extracted teeth. The results of electron microscopy clearly demonstrate that optimizing parameters such as mode of delivery of water and air spray, rotary tool drive can solve the following problems at preparing dental hard tissues – overheating of the tooth structure; rough surface after preparation; chipped and cracked enamel; as an adhesive surface
ВЛИЯНИЕ ТЕРМООБРАБОТКИ НА ЭФФЕКТИВНЫЙ ЗАРЯД И ПЛОТНОСТЬ ПОВЕРХНОСТНЫХ СОСТОЯНИЙ В СТРУКТУРАХ С КРЕМНИЕВЫМ ЗАТВОРОМ
Authors: Хасанов А.И. , Мустафаев Г.А.
Published: May 2024

Проведены исследования по влиянию условий термообработки МНОП структур перед металлизацией на эффективный заряд и плотность быстрых поверхностных состояний. Все виды обработки проводились в течение 30 мин. Показано, что обработка в азоте уменьшает и даже может сделать отрицательным заряд в окисле и увеличивает плотность поверхностных состояний; обработка в водороде снижает плотность поверхностных состояний. Структуры с затвором, легированным фосфором, имеют меньший заряд в окисле, чем в случае легирования бором. Для структур с затвором, легированным бором соотношение между толщинами слоев окисла кремния и нитрида кремния 900А/300А приводит к меньшему заряду, чем для слоев окисла кремния и нитрида кремния 300А/300А.
РОЛЬ ДИСКУРСИВНОГО АНАЛИЗА В ПЕРЕВОДЕ
Authors: Даутмурзаева З.Г.
Published: May 2024

Дискурс-анализ (ДА) – это дисциплина, изучающая взаимосвязь между языком и контекстом, в котором он используется. Другими словами, дискурс-анализ – это раздел прикладной лингвистики, который исследует используемый язык. Как объясняет Маккарти, «эта область исследований выросла из работы в различных дисциплинах 1960-х и 1970-х годов, включая лингвистику, семиотику, психологию, антропологию и социологию» [5, с. 5]. Одной из наиболее интересных областей исследований, на которую в последнее время повлиял анализ дискурса, является недавно зародившееся направление под названием «Исследование перевода». Эта новая область исследований, которая набирает силу, углубляется в систематическое изучение перевода. Предполагается, что ДА и исследования перевода имеют много общего. Некоторые из областей исследований, на которые повлиял ДА, – это систематическая функциональная грамматика Холлидея, модель оценки качества перевода Джулиана Хауса и типология текста Кэтрин Рейзис в переводе. Целью данной статьи является анализ этих понятий и терминов в контексте переводоведения.
NL2SQL For Chatbot with Semantic Parsing Using Rule-Based Methods
Authors: Kurniawan Adi , Abdiansah Abdiansah , Utami Alvi Syahrini
Published: May 2024

Structured Query Language (SQL) is a command language that allows users to access database information. Ordinary people generally donot know how to make queries with SQL to a database. The chatbot is acomputer program developed to interact with its users via text or voice. In this study, chatbots were developed to help and facilitate users intheNatural Language to Structured Query Language (NL2SQL) process tosearch for information in an Academic Information Systemdatabasewith semantic parsing using a rule-based method that accepts input inthe form of interrogative sentences or order. In the Natural Language toStructured Query Language (NL2SQL) process several problems arise, namely input problems with unique parameters for the knowledge base, and slow searching or translation processes, which make Natural Language to Structured Query Language (NL2SQL) inef icient, problems This problem will be solved using a semantic parsingapproach using a rule-based method that is proven to be ef icient insolving issues such as the Natural Language to Structured QueryLanguage (NL2SQL) process. The results showed that the semanticparsing approach using the rule-based method succeeded in obtainingan accuracy rate of 96.72% using 122 test data in the formof questionsentences or command data about the Academic Information Systemof the Department of Informatics Engineering, Sriwijaya University inIndonesian, and an average execution time of 50.68 milliseconds. seconds or 0.05 seconds.
INVESTIGATION OF THERMAL CONDUCTIVITY IN SINGLE-WALLED (n,n) CARBON NANOTUBES USING MOLECULAR DYNAMICS SIMULATION
Authors: Mohammed Hashim Albashir  , Hajhamed Diab  , Hashim Gad Elseed
Published: May 2024

Single-walled carbon nanotubes (SWCNTs) are captivating materials renowned for their outstanding thermal properties and diverse applications in nanotechnology. This study utilizes molecular dynamics simulations to investigate the factors influencing thermal conductivity in SWCNTs, namely diameter, length, temperature, and defects. Results reveal that thermal conductivity exhibits an increase with both diameter and length, with values ranging from 3100 to 3400 W/m·K for diameters varying from 0.68 to 1.70 nm , and from 2800 to 3700 W/m·K for lengths ranging from 20 to 200 nm . Conversely, thermal conductivity demonstrates a decrease with rising temperatures, with values dropping from 3400 to 2600 W/m·K as temperature increases from 100 to 700 K . Furthermore, the presence of defects significantly diminishes thermal conductivity, as illustrated by reductions from 3200 to 2900 W/m·K for single vacancy defects and further to 2500 W/m·K for double vacancies. These findings insights into the thermal behavior of SWCNTs, enhancing our understanding of their thermal properties and broadening their potential applications, including in nanoscale cooling and nanoelectronics
WALKING IN THEIR SHOES: A PHENOMENOLOGICAL STUDY OF THE LIVED EXPERIENCES OF TEACHERS MANAGING STUDENTS WITH DISRUPTIVE BEHAVIOR
Authors: Ericka T. Villaceran  , Nessim B. Mediodia  , Kimberly Yvonne A. Bisaya  , Wenefredo E. Cagape
Published: May 2024

This study focuses primarily on the lived experiences of secondary education teachers who work with students exhibiting disruptive behavior. The research employs a qualitative phenomenological approach, utilizing semi-structured in-depth interviews with a sample of five teachers from a secondary school in Barangay Sigaboy who are responsible for managing students with disruptive conduct. The selection of participants was done through purposive sampling. Thematic analysis was employed to evaluate the data, which facilitated the identification of key statements pertaining to the challenges, coping methods, and insights of secondary teachers in managing disruptive conduct exhibited by their students. Upon deliberation, 2 general themes surfaced breaking into 2 subthemes of each result. The results have shown that the first theme: learner’s background have described the types of learners and the reason for disruptions. It is evident that secondary teachers experience varied learners that disrupts the learning process and carries different reason of disruptions. The second theme: academic background exposed the teachers’ emotional attachments and strategies in the disruptive behavior. This study describes the lived experiences of 5 secondary teachers in the journey of educating young adults.
KEYWORDS: Secondary Teachers, Disruptive Behavior, Lived Experience