bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of nitrogen and carbon sources and salt stress on the bioactive components concentration in Scenedesmus obliquus
Authors: Luz Marina Zapata  , Mariana Jiménez-Veuthey  , Natalia Agustina Sacks  , Gina Fiorella Vezzosi-Zoto
Published: March 2022

In Scenedesmus obliquus culture, the effects of different nitrogen and carbon sources and saline stress on total carotenoids, total proteins and total phenols contents were investigated. Microalgae in Allen & Arnon culture medium were cultivated, until reaching the stationary phase. Then, sodium nitrate or urea as nitrogen source and sodium acetate or glucose as carbon source, were incorporated. Additionally, sodium chloride was added for cause saline stress. Fourteen treatments were carried out, during 40 days. Differences in bioactive components concentration were observed for the different nitrogen and carbon sources from day 26. When 0.24 g/L of urea were used, 3 times more of total carotenoids were obtained than when sodium nitrate was used; while, with 3.68 g/L of glucose, 1.5 times more of total carotenoids were reached than with sodium acetate was used. Total proteins concentration was 1.9 times higher when 0.24 g/L of urea and 5.02 g/L of sodium acetate were utilized as nitrogen and carbon sources, respectively. With 31.00 g/L of urea 4 times more of total phenols were obtained than with sodium nitrate; while, 12 times more of total phenols were achieved with 3.68 g/L of glucose than with sodium acetate. Saline stress caused a reduction in the bioactive components of interest. The highest concentrations obtained were: 513.20±13.21mg β-carotene/gdwc, 7.25±0.34 mg BSA/gdwc, and 16.78±0.54 mg GAE/gdwc. Therefore, this study confirmed that Scenedesmus obliquus microalgae developed strategies to adapt to the new conditions caused by the nitrogen and carbon sources incorporation, causing changes in the concentration of bioactive components.
Síndrome de Fahr con hipoparatiroidismo primario como causa de epilepsia refractaria
Authors: Mora-Garzón Edwin Ronald , Restrepo Valencia Cesar Augusto , Parra Santacruz Cindy Paola , Rodas Restrepo Valentina
Published: March 2022

Introducción: el hipoparatiroidismo primario se caracteriza por niveles inadecuadamente bajos de hormona paratiroidea (PTH), lo cual conlleva un estado de hipocalcemia crónica que, de no corregirse, genera perturbaciones predominantemente de tipo neuromuscular.Objetivo: se presenta un caso de una paciente con hipoparatiroidismo primario con el fin de mostrar sus característicasclínicas, criterios diagnósticos y patologías diferenciales. Se evidencia la importancia de un diagnóstico temprano y de untratamiento oportuno que impacte en el pronóstico y calidad de vida de los pacientes.Presentación del caso: se presenta el caso de una mujer de 23 años con antecedente de epilepsia de difícil control desde los dos meses de edad, manejada con múltiples anticonvulsivantes, pero con persistencia de crisis convulsivas. En neuroimágenes de control realizadas a sus 22 años, se reportan calcificaciones ganglio-basales y frontales y es derivada a la consulta de Endocrinología para estudios. En los estudios de perfil fosfocálcico se evidenció hipocalcemia severa, hiperfosfatemia y PTH suprimida.Discusión y conclusión: se realiza el diagnóstico de síndrome de Fahr secundario a hipoparatiroidismo primario, por lo que se instaura tratamiento con carbonato de calcio y calcitriol, lográndose control de los episodios convulsivos y finalmente suspensión de drogas anticonvulsivantes. Estos hallazgos sugieren incluir al hipoparatiroidismo primario como diagnóstico diferencial de pacientes con epilepsia refractaria.
Myo-inositol in geriatric patients with cognitive impairment
Authors: Aldossary Nasser , Kotb Mamdouh , Elsifey Ayman , Ahmed Yassmin , Ahmed Ali
Published: March 2022

Background & Objective: Cognitive impairment, in geriatric population, is reported in patients with depression, mild cognitive impairment (MCI), and dementia. MCI is the transitional stage before dementia, with annual conversion rate to dementia of about 20%. Early diagnosis of the underlying cause of cognitive impairment in geriatric patients is crucial for proper management. This could be achieved through proton magnetic resonance spectroscopy. We aimed to study the difference of frontal, posterior cingulate gyrus, and occipital myo-inositol (MI), and myo-inositol/creatine (MI/Cr) ratio between patients with MCI, and cognitive impairment associated with geriatric depression; and study if these metabolites could differentiate between MCI and cognitive impairment associated with geriatric depression.
Methods: Geriatric patients with MCI, and elderly patients with depression associated with cognitive impairment, along with sex and age matched healthy control were evaluated clinically and underwent neuropsychological testing, laboratory tests as well as brain MRI and proton magnetic resonance spectroscopy at baseline. Patients were reevaluated clinically, and neuropsychologically at 12, and 24 months from baseline.
Results: The present study included 62 subjects. Patients with MCI had significantly higher posterior cingulate gyrus, occipital MI/Cr ratio, and frontal MI and MI/Cr ratio than normal controls. No differences were seen between geriatric patients with cognitive impairment associated with depression and those with MCI and healthy control in any of the studied metabolites in the studied brain regions.
Conclusion: Elevated posterior cingulate gyrus, occipital, and frontal MI/Cr ratio, and frontal MI level could help to identify patients with MCI from healthy control, but could not differentiate between MCI and cognitive impairment associated with depression.
Craniotomy versus endoscopic approach in basal ganglia haemorrhage: A systematic review and meta-analysis
Authors: Tan Tze Khiang , Merola Joseph , Zaben Malik , Gray William , Leach Paul
Published: March 2022

Objectives: Basal ganglia haemorrhage (BGH) is the most common type of intracerebral bleed with high morbidity and mortality rate. Despite advancements in minimally invasive techniques in recent years, the efficacy between craniotomy and endoscopic approach for BGH is still debatable. The aim of this systematic review and meta-analysis was to evaluate the outcomes of craniotomy and endoscopic approach for BGH.
Methods: Databases of Pubmed, EMBASE, MEDLINE and CENTRAL were systematically searched from its inception until December 2020. All randomized clinical trials and observational studies comparing craniotomy versus endoscopic approach in BGH were included.
Results: Twelve studies enrolling 1,297 patients (craniotomy:675, endoscopy:632) were included for qualitative and quantitative analysis. Endoscopic approach was associated with significantly lower postoperative mortality (OR:0.35, P<0.001), higher haematoma evacuation rate (MD:4.95, P<0.001), shorter operative time (MD:-117.03, P<0.001), lower intraoperative blood loss (MD:-328.47, P<0.001), higher postoperative Glasgow Coma Scale (GCS) (MD:1.14, P=0.01), higher postoperative Glasgow Outcome Scale (GOS) (MD:0.44, P=0.05), shorter length of hospital stay (MD:-2.90, P<0.001), lower complication rate (OR:0.30, P=0.001), lower infection rate (OR:0.29, P<0.001) and lower modified Rankin Scale (mRS) (MD:-0.57, P=0.004) compared to craniotomy. No significant difference was detected in re-operation, and re-bleeding.
Conclusion: The best available evidence suggest that endoscopic approach has better outcomes in mortality rate, operative time, haematoma evacuation rate, intraoperative blood loss, length of hospital stay, mRS, postoperative GCS and GOS compared with craniotomy in the management of BGH. However, there is a need for high quality randomised controlled trials with large sample size for definitive conclusions.
Brown-Séquard syndrome: An uncommon presentation of hydatid cyst
Authors: Prasad Pratibha , Verma Prem Shanker
Published: March 2022

Primary spinal hydatid cyst account for 1% of all cases of hydatid disease. In Indian literature, few cases are reported. We report a case of 27-year-old immunocompetent Indian male patient presenting with brown sequard syndrome like presentation who later was diagnosed with extramedullary intradural multicystic large hydatid cyst. Following surgical removal of hydatid cyst, he was asymptomatic and was discharged on albendazole. There was no relapse in one year follow up. This case is being reported due to its rarity of occurence and presentation.
Therapeutic potential of cinnamon for neurological disorders: A mini-review
Authors: Ahmadi Ali , Naziri Mahdyieh , Fallahpour Fatemeh , Gholami Kosar , Arabpour Javad , Pazeshgare Fateme , Akbarzadeh Diba , Ansari Arina , Sabri Hamoun , Deravi Niloofar
Published: March 2022

An increasing amount of evidence suggests that cinnamon, due to its rich source of polyphenol content, may exert antioxidant and anti-inflammatory properties, hence could be used in the treatment of variety of diseases. in this regard, many studies explored the effects of cinnamon and its bioactive components (coumarin, cinnamic acid, cinnamaldehyde and type A procyanidin polymers) on various neurological diseases including Parkinson’s disease, neuroinflammation, multiple sclerosis, brain injury, Alzheimer’s disease, migraine, and hyperactivity. The present study attempts to review available data concerning the therapeutic potential of cinnamon and its derivatives in neurological disorders.
The sequelae of a neglected thoracolumbar cystic spinal lesion
Authors: Goo Zhen Qiang , Sockalingam Sutharshan , Cham Chun Yoong , Raja Aman Raja Rizal Azman , Veerakumaran Jeyaganesh , Ganesan Dharmendra
Published: March 2022

Large thoracolumbar intradural cystic lesions are rare. The possible diagnosis would be a cystic nerve sheath tumour, dural ectasia or arachnoid cyst. We report the first case of a neglected giant thoracolumbar spinal cystic tumour that had resulted in progressive deleterious spinal column deformity due to bony erosion precluding any form of surgical remedy. In the same case, another fatal sequela of a neglected spinal cystic tumour is a spontaneous rupture resulting in an acute hydrocephalus and mortality. This case impresses the natural history of a spinal cystic lesion. The take home point would be these cases need early surgical intervention is indicated to prevent sequelae that has been described.
Lactate as an important biomarker of cerebrospinal fluid in infectious diseases of the central nervous system: A comprehensive literature review
Authors: Vélez-Paez Jorge L. , Rueda-Barragán Fernando E. , Torres-Carpio Daniel A. , Guerrero Fausto M. , Romero Juan J. , Vásconez-González Eduardo , Ortíz-Prado Esteban
Published: March 2022

Central nervous system (CNS) infections are a group of diseases, where meningitis (associated or not to neurosurgical interventions) and bacterial ventriculitis have been studied for many years in order to establish early diagnosis methods through direct therapy to reduce morbidity and mortality in this population. Analysis of the cerebrospinal fluid (CSF) is an important source of information for diagnosis of neuroinfection. Lactate concentration in the cerebrospinal fluid has a value independent of plasma because it does not cross the blood-brain barrier, therefore, constitutes the end-product of the bacterial anaerobic glycolysis being the primary source of lactate in the CSF. Therefore, it has a great tool in the diagnostic approach of bacterial meningitis, however, reference values ​​are not warranted. Objective: The authors present the latest scientific evidence on the use of lactate as a diagnostic method for two neurological pathologies with highest incidence on population, establishing a translational approach to clinical practice. Methods: A comprehensive literature review was carried out. We describe the results of a structured search based on keywords infection, meningitis, ventriculitis, bacterial, cerebrospinal fluid, and lactate, vía Medline, Scopus, WoS, EMBASE, and LATINDEX databases. Conclusion: Lactate in a CSF sample is useful to determine the bacterial etiology in patients with suspected meningitis. CSF lactate value equal or higher than 4 mmol/l could indicate bacterial meningitis about 90% of probability. Lactate value is identical in patients with ventriculitis; however, it cannot be established as neuroinfection, therefore, we should use another diagnostic method.
Objective: This work will present the updated scientific evidence regarding the use of lactate as a diagnostic method for two neurological entities with high incidence in our population, establishing a translational approach to our clinical practice.
Methods: A comprehensive literature review was carried out we wrote the results of a structured search with the keywords infection, meningitis, ventriculitis, bacterial, cerebrospinal fluid, and lactate, in both English and Spanish within the Medline, Scopus, WoS, EMBASE, and LATINDEX databases.
Conclusion: Measuring lactate in a CSF sample is useful to determine the bacterial etiology in patients with suspected meningitis, a CSF lactate value greater than or equal to 4 mmol / l means that a patient will have bacterial meningitis with certainty greater than 90% However, the lactate value is the same in a patient with ventriculitis, it cannot be established with total certainty that it is a neuroinfection, therefore, we should use some other diagnostic method
Literally Resistance: The basic concerns
Authors: Kamran Shahzad Muhammad
Published: March 2022

ادبی مزاحمت: بنیادی مباحث

This article defines resistance and examines literal and terminological concepts of resistance with a critical point of view. In addition, the article discusses in detail, the types of condemnation (individual resistance, collective resistance), cases, scope and impact of resistance on the society. At the end the evolutionary stages of resistance and resistance as a literary term are examined and conclusions, are drawn.
Diversity, Distribution and Indigenous uses of Medicinal Plants of Nirmand Block in Seraj Valley, Kullu District of Himachal Pradesh
Authors: Vidyarthi Shalini , Samant Sher , Sharma Pankaj
Published: March 2022

The Indian Himalayan Region is one of the richest reservoirs of biological diversity in the world and is considered as a store house of the valuable medicinal plants. In the remote areas of Indian Himalaya, the inhabitants are largely dependent on plants for curing various diseases/ailments. But, due to urbanization and modernization, the indigenous knowledge and traditional practices of medicinal plants are vanishing fast. The Kullu district of Himachal Pradesh is one of the twelve districts, and is a veritable emporium of herbal plants and consists of five blocks (Kullu, Anni, Banjar, Naggar and Nirmand). Nirmand Block (31o25’28"N and 77o34’36"E) covers an area of 77.45 km2. The medicinal plants wealth of Nirmand valley has not been explored so far. Therefore, an attempt has been made to; (i) assess the medicinal plants diversity; (ii) document indigenous uses and practices; (iii) analyze for nativity and endemism; and (iv) suggest strategy for the conservation and management of the species. The present study recorded first hand information on 41 species of medicinal plants belonging to 39 genera and 29 families from the Nirmand Block. The recorded species represent trees (06 spp.), shrubs (06 spp.) and herbs (29 spp.). Different parts of these species, such as whole plants, roots, leaves, flowers, fruits, seeds, stems, barks, etc. were used by the inhabitants for curing various diseases. Twenty seven (27) species were natives and 14 species non-natives to the Himalayan region. Due to changing environmental conditions and habitat degradation, the populations of many species are depleting fast. Therefore, studies on habitat ecology, development of conventional and in-vitro propagation protocols and introduction in cultivation and natural habitats are suggested.
Rapid and Visual Detection of Barley Yellow Dwarf Virus by Reverse Transcription Recombinase Polymerase Amplification with Lateral Flow Strips
Authors: Kim Na-Kyeong , Lee Hyo-Jeong , Kim Sang-Min , Jeong Rae-Dong
Published: March 2022

Barley yellow dwarf virus (BYDV) has been a major viral pathogen causing significant losses of cereal crops including oats worldwide. It spreads naturally through aphids, and a rapid, specific, and reliable diagnostic method is imperative for disease monitoring and management. Here, we established a rapid and reliable method for isothermal reverse transcription recombinase polymerase amplification (RT-RPA) combined with a lateral flow strips (LFS) assay for the detection of BYDV-infected oat samples based on the conserved sequences of the BYDV coat protein gene. Specific primers and a probe for RT-RPA reacted and optimally incubated at 42 o C for 10 min, and the end-labeled amplification products were visualized on LFS within 10 min. The RT-RPA-LFS assay showed no cross-reactivity with other major cereal viruses, including barley mild mosaic virus, barley yellow mosaic virus, and rice black streaked dwarf virus, indicating high specificity of the assay. The sensitivity of the RT-RPA-LFS assay was similar to that of reverse transcription polymerase chain reaction, and it was successfully validated to detect BYDV in oat samples from six different regions and in individual aphids. These results confirm the out-standing potential of the RT-RPA-LFS assay for rapid detection of BYDV.
Physiological and Biochemical Changes in Lucerne (Medicago sativa) Plants Infected with ‘Candidatus Phytoplasma australasia’-Related Strain (16SrII-D Subgroup)
Authors: Ayvacı Hümeyra , Güldür M. Ertuğrul , Dikilitas Murat
Published: March 2022

Changes in physiological and biochemical patterns in lucerne plants caused by the presence of ‘Candidatus Phytoplasma australasia’, which is one of the significant pathogens causing yield losses in lucerne plants, were investigated. Significant differences were evident in total chlorophyll, chlorophyll a, chlorophyll b, and protein amounts between ‘Ca. Phytoplasma australasia’-positive and negative lucerne plants. Stress-related metabolites such as phenol, malondialdehyde, and proline accumulations in ‘Ca. Phytoplasma australasia’-positive plants were remarkably higher than those of phytoplasma-negative plants. As a response to disease attack, phytoplasma-positive plants exhibited higher antioxidant enzymes (peroxidase and catalase) and non-enzymatic metabolite responses such as jasmonic and salicylic acids. We state that partial disease responses were revealed for the first time to breed resistant lucerne lines infected by ‘Ca. Phytoplasma australasia’.
Pengembangan Modul Pembelajaran Perawatan Berkala Sistem Pendingin Air Pemeliharaan Mesin Sepeda Motor
Authors: Ruwaida Rahmiati , Dabet Abubakar , Siraj Siraj , Taufiq Taufiq
Published: March 2022

Module development is one of the efforts to increase students' independence in learning. Research objectives: (1) module development; (2) module feasibility; (3) student learning outcomes on the material for periodic maintenance of the water cooling system. The type of research is Research and Development. The instruments used were observation, interviews, questionnaires, and documentation. Data analysis techniques include: media and material expert validation, percentage qualitative analysis, and t-test analysis. The results of the study show that: (1) module development makes students more active and learn independently, 2) validation results from module development are very suitable, obtained material expert validation values of 94.16% and 95.55%, and validation values from experts media by 93.78% and 92.42%. 3) student learning outcomes have increased as evidenced by the score obtained by the experimental class of 94.6%.
Peran Whistleblowing System dan Teknik-teknik Audit pada Audit Investigatif dalam Pengungkapan Fraud
Authors: Hidayah Vina Nur , Nurcahya Yulida Army
Published: March 2022

This study aims to determine the role of the whistleblowing system and audit techniques in investigative audits in disclosing fraud. As we know that many frauds have occurred in Indonesia, so it is necessary to review the role of the whistleblowing system and audit techniques. This whistleblowing system application is used to prevent fraud. The reporting party in this application has been kept confidential, so that the reporter feels safe. In this study, the method used is a qualitative method with a literature review in the journals of previous researchers. Sources of data obtained from journals, books and the internet in accordance with the theme of this study.
Profil Perilaku Perundungan Terhadap Siswa Kelas VIII SMPN 5 Kota Serang Tahun Ajaran 2021/2022
Authors: Djadjas Reni Nur'aeni , Rahmawati Rahmawati , Dalimunthe Raudah Zaimah
Published: March 2022

Students will go through time after time, when students enter school, students will feel unfamiliar with the new environment, and new friends. When entering a new environment and meeting new friends, students will be anxious, when students cannot interact with the new environment in class, students find friends who will become victims of bullying. This research uses descriptive quantitative method. The population taken is junior high school students and the number of respondents is 200 students through random sampling. The results of this study indicate that the bullying behavior of students at SMPN 5 Kota Serang tinggi. on verbal indicators there are about 34% in the high category, then cyberbullying there are about 28.08% in the high category, Physical bullying is around 27.58% in the medium category, doing physical bullying is around 27.58% , indirect is in the low category of 18.8%.
Manajemen Pendidikan Anak Usia Dini di TK Bunda Wardah Kecamatan Bacukiki Barat Kota Parepare
Authors: Hasnawati Sri , Jufri Muhammad
Published: March 2022

The background of this research is that early childhood management is very important and BUNDA WARDAH Kindergarten already has good management. Based on this background, the authors are interested in conducting research that examines the management of early childhood education in Bunda Wardah Kindergarten, West Bacukiki District, Parepare City. The formulation of the problem in this study is "how is the management of early childhood education in Bunda Wardah Kindergarten, West Bacukiki District, Parepare City?". This study aims to determine whether the process of early childhood education management in Bunda Wardah Kindergarten is in accordance with the implementation steps or not. The type of research that the author uses is phenomenological. The object of this research is the management of early childhood education. Data collection techniques in this study using interviews, observation and documentation. While the data analysis technique uses descriptive analysis techniques which include collecting data, reducing data, presenting data, and drawing conclusions.
To Tidy or not When Teaching R Skills in Biology Classes
Authors: Martin Andrew
Published: March 2022

An essential skill for STEM undergraduates is the ability to understand the world by manipulating, visualizing, and analyzing data to make or evaluate claims. Current online debate, without peer-reviewed literature, explores which of two common R syntax environments (base R or tidyverse) is best for teaching novice R users. In an in-person undergraduate course on evolutionary biology, we implemented two coding curricula: one using base R (n = 49 students) and the other using tidyverse (n = 58 students). We compared these two curricula using several dimensions of student success: interpretation of syntax, creation of appropriate data visualizations and analyses,      and an absence of sex bias in performance. A linear model revealed prior experience had the largest estimated effect, followed by syntax environment; sex had the smallest effect. Pedagogical approaches that ensure students have repeated opportunities for practice and that implement techniques to overcome student frustration and anxiety are likely more important than syntax environment when learning coding in biology classes. Furthermore, the small effect of sex combined with the high proportion of females in the biological sciences suggests introducing computer programming in biology may allow females to discover interest and ability that they may not have had if computer programming was the sole propriety of computer science departments.
What Should the Future of Learning Look Like? Looking Back, Looking Forward
Authors: Ipperciel Donald
Published: March 2022

This paper explores a possible and desirable future of technology-enhanced teaching and learning in higher education. It takes a normative lens that defines what ‘ought to be,’ based on considerations grounded in the philosophy of education. In other words, its aim is more prescriptive than predictive. It will suggest we embrace technology only to the extent that it brings us closer to realizing the pedagogical ideals of educability, personalization, and active, experiential learning. This paper examines how these principles prove helpful in prioritizing the technologies worthy of being adopted and how technology can contribute in a meaningful way on all three fronts. In addition to the principles of pedagogical innovation, practical considerations for realizing the future state will be identified. In this context, it is argued that the envisioned future of technology-enhanced teaching and learning in higher education can come to fruition only when education becomes collaborative and course creation builds incrementally on previous educational iterations, made possible through institutional support and collaborative design.
Analysis of trend and temporal variability in rainfall over Northeast India
Authors: SINGH PRIYANKA , KUMAR NARESH
Published: March 2022

Study of rainfall trend is of great importance in India where food security and consequently economy primarily dependent on rainfall. Present work is carried out to perform the detailed analysis of temporal variability in North East India rainfall. Temporal variation in monthly, seasonal and annual rainfall over northeast India (NEI) is studied using monthly data for 150 years (1857-2006). Magnitude of trend in time series data is determined by using both parametric and non-parametric test i.e linear regression and Man-Kendall test. Analysis of data suggests a significant decrease in monsoon rainfall and increase in post monsoon rainfall. Influence of global teleconnection like North Atlantic Oscillation (NAO) and Southern Oscillation (SO) on NEI rainfall is also studied to address the temporal variation. To carry out detail analysis, time series rainfall data is further divided into five normal periods of 30 year each: 1857-1886 (P1), 1887-1916 (P2), 1917-1946 (P3), 1947-1976 (P4) and 1977-2006 (P5) and trend analysis on seasonal rainfall performed for above mentioned periods. Decreasing trend for four out of the five classified periods for monsoon rainfall and significant increase in three periods obtained for post monsoon rainfall. 11 year running mean also calculated for annual as well as seasonal rainfall to see the changes in rainfall pattern.
Effect of weather variability on soil temperature, enzyme activities and nutrient availability under pear tree orchard in semi arid condition
Authors: YADAV B.K. , PAL R.K.
Published: March 2022

The present study was conducted to quantify the effect of weather variability on soil temperature, enzyme activities and nutrient availability in arid soil under semi arid condition of Bathinda district of Punjab. In this context, soil samples were collected on weekly basis for three consecutive years (2016-2018) randomly from pear tree (Pyrus communis L.) orchard at three depths: 0-5 cm (top), 5-15 cm (middle) and 15-30 cm (lower), while, soil temperature observations for the respective depths were taken. The value of organic carbon content in soil decreased with increase in soil depth and reported 24 and 40 per cent lower organic carbon in middle and lower depths, respectively. Similarly, K content was also found more at 0-5 cm soil depths and decreased with depth. While, the value of dehydrogenase, acid and alkaline phosphatase and P was found more at 5-15 cm soil depth. Furthermore, nutrients (P and K) availability was found slightly higher in 2017 followed by 2018 and 2016. Alternatively, due to more moderate to heavy rainfall activities during 2016, soil nutrients were leached down from upper layers than rest years. Additionally, among the soil depths and years of study, soil temperature was watched higher than air temperature. Lesser deviations in soil enzyme activities and nutrient availability were found during the investigation year of 2016 followed by 2017 and 2018, likewise, lesser deviations were additionally found in 2016 than rest of the years in regard of weather parameters. Among soil depths and years of study, correlation coefficient (r) value between air and soil temperature was found positive and significant at 1% probability level. However, In respect of bright sunshine and rainfall vs. soil temperature, non-significant but positive correlation was found except 2018 for rainfall which was significant.
Pengaruh Pelatihan dan Disiplin Kerja terhadap Kinerja Guru SMA Swasta di Wilayah Kecamatan Parung Panjang dan Tenjo Kabupaten Bogor
Authors: Sudarso Aden Prawiro , Narimawati Umi , Affandi Azhar , Priadana Sidik , Erlangga Heri
Published: March 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh pelatihan dan disiplin kerja terhadap kinerja Guru SMA Di Wilayah Kecamatan Parung Panjang dan Tenjo Kabupaten Bogor baik secara parsial maupun secara simultan. Metode yang digunakan adalah metode asosiatif. Teknik sampling yang digunakan adalah random sampling menggunakan dengan sampel sebanyak 142 responden dari populasi 220 dengan menggunakan rumus slovin. Hasil penelitian ini adalah Pelatihan berpengaruh signifikan terhadap kinerja guru dengan koefisien determinasi sebesar 40,5%. Disiplin kerja berpengaruh signifikan terhadap kinerja pegawai dengan koefisien determinasi sebesar 43,2%. Pelatihan dan disiplin kerja berpengaruh signifikan terhadap kinerja pegawai dengan persamaan regresi Y = 6,031 + 0,382X1 + 0,469X2. Nilai korelasi sebesar 0,754 artinya variabel bebas dengan variabel terikat memiliki tingkat hubungan yang kuat dengan koefisien determinasi sebesar 56,8% sedangkan sisanya sebesar 43,2% dipengaruhi faktor lain. Uji hipotesis diperoleh nilai F hitung > F tabel atau (91,540 > 2,670). Dengan demikian H0 ditolak dan H3 diterima. Artinya terdapat pengaruh signifikan secara simultan antara pelatihan dan disiplin kerja terhadap kinerja Guru SMA Swasta  Di Wilayah Kecamatan Parung Panjang dan Tenjo Kabupaten Bogor.
Myo-inositol in polycystic ovary syndrome: a systematic review and positioning of its use
Authors: Ribas Filho Durval , Nogueira-de-Almeida Carlos Alberto , Zotarelli-Filho Idiberto José
Published: March 2022

Introduction: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disease among women of reproductive age 6 to 15% its presentation is complex and heterogeneous and is characterized by clinical and laboratory findings of hyperandrogenism, oligo-anovulation, metabolic abnormalities such as insulin resistance (IR), overweight, obesity, type 2 diabetes mellitus, dyslipidemia and increased risk of cardiovascular disease. Objective: To evaluate the effects of myo-inositol in pregnant and non-pregnant women with polycystic ovary syndrome in relation to fertility improvement, gestational outcomes, and metabolic and hormonal parameters. Methods: Data from randomized clinical trials on the efficacy of myo-inositol in women with PCOS were used in this review. The PubMed database was used for literature search. Results: Insulin resistance is one of the mechanisms that explain the emergence of metabolic and reproductive changes in women with PCOS. When compared to placebo, myo-inositol was effective in improving fertility, increasing ovulation and fertilization rates, in addition to improving metabolic parameters as indicators of insulin resistance (HOMA index). Even when compared to more traditional insulin sensitizers like metformin, myoinositol showed similar efficacy in restoring fertility. Myo-inositol was also effective when associated with clomiphene acetate and in women undergoing in vitro fertilization processes. There was also an improvement in pregnancy outcomes and a reduction in the risk of developing gestational diabetes with the use of myo-inositol. Conclusions: Myo-inositol improves clinical and laboratory parameters in both pregnant and non-pregnant PCOS patients, increasing the fertility rate and improving pregnancy outcomes.
APPLICATION OF STEREOMETRY IN SCHOOL COURSES
Authors: Saparkanova B. M. , Taskynbayeva G. Z.
Published: March 2022

In today’s modernized education system, it is important to provide students with a comprehensive education and teach them to apply the acquired knowledge in practice. The subject of geometry, taught in the school course, also contributes to the student’s knowledge of the world around him, the study of the properties of objects in space. The article discusses the features of one of the sections of geometry-stereometry, similarities and differences in the field of planimetry. The purpose and essence of teaching the field of stereometry in the school course are also indicated, as well as the benefits of stereometry for students are analyzed.
INTERACTION OF FAMILY AND SCHOOL IN THE CONTEXT OF INCLUSIVE EDUCATION
Authors: Kenzhebekova У. M. , Kavdyrova A. A.
Published: March 2022

Currently, an inclusive education system is organized in the process of adaptation of children with special educational needs to the environment. This process is very relevant in the world and in the country.

The main purpose of the article «interaction of family and school in inclusive education» is to establish close ties between parents raising a child with special educational needs and the staff of an educational secondary school, the organization of trusting and strong relationships with school teachers.

The main subject participating in the inclusive education system is the child, the school staff and the parent.

A parent is a person who occupies a special place in the education of a child with special educational needs, adaptation of the child to the environment. Psychological and pedagogical assistance to parents is organized by the school staff. The joint activity of specialists (teachers, psychologists, speech therapists, speech pathologists, social educators) has a huge impact on the development of the child.

When conducting correctional and developmental classes, parents receive personal information about their child, special consultations are given for parents. Parents should take an active part in the correctional and developmental activities of the child, conduct repeated classes outside of school hours (fixing the studied material at home, medical treatment).
THE STATUS OF THE KAZAKH LANGUAGE IS A LANDMARK FOR THE FUTURE OF THE NATION
Authors: Abduova B. S. , Tulesheva G. K.
Published: March 2022

About the sphere of use of the Kazakh language of the present time both in social networks and in public places. We can say that compared to previous years, we have achieved significant results over the past five or six years. After Independence, the role of the Kazakh language in the field of socio-economic, scientific, technical and general culture has increased, and the volume of use has expanded. The requirements for the study of the Kazakh language have increased, especially in other language groups of the university. In this regard, the knowledge of the Kazakh language by students of Russian groups is guided by the basics of modern education in the educational process. Listening to the Kazakh language, speaking, reading, writing, mastering high-quality knowledge and culture of the Kazakh language is a prestigious duty of Kazakhstanis. Along with international processes, the development-oriented education system also requires a new organization of all branches in order to study it from a different angle. Teaching true connoisseurs of the language, national historical and cultural traditions, who understand the role of the Kazakh language in the world community, is very important today. Only with the help of competent language learning, the future of the Kazakh people can be bright.
STUDENT YOUTH TRAINING AT THE MODERN STAGE OF EDUCATION DEVELOPMENT
Authors: Gonenko S. V. , Muldinova E. S.
Published: March 2022

Any field of activity, within the framework of modern scientific and technical development, has undergone, and continues to make more and more adjustments to its structure. Changes in the structure of the sphere of education, in particular - the discipline "Physical culture", is no exception.

The main documentation on which the lessons on the subject are based is the educational-methodological complex of the discipline (EMCD), the working curriculum (WC), as well as their constituent parts.

In the current conditions (pandemic), education had, for the most part, to switch to such a type of education as distance learning. Physical education teachers, coaches and teachers had to find new methods and means of conducting classes.

Changing the methods (even coordinating ones) in conducting classes in the discipline "Physical culture" does not cancel its purposefulness. The goal - upbringing, development and maintenance of a healthy lifestyle among student youth, still remains relevant.
MYTHOLOGICAL IMAGES IN PROSE POEMS by I.S. TURGENEV
Authors: Grun A. V. , Zhaxylykova A. N.
Published: March 2022

As early as the beginning of the 20th century, linguists noted the growing interest of writers in mythology, which prompted them to study this phenomenon in more detail. Although traces of mythology can be found throughout the history of world literature. After all, mythological motifs contributed to the creation of images, themes and plots known to the whole world. The mythological basis of a literary work is the highest level of intertextuality and the cultural immersion of the reader's imagination into the literary canvas of a work of art. Through the analysis of mythological images, additional authorial meanings and the ideological idea of any writer are revealed. I.S. Turgenev is very stingy in choosing emotionally colored vocabulary, but his vivid images, sometimes developing into symbols, are all the more valuable. "Poems in prose" have not been studied in the literary world from the point of view of mythotectonics, which determines the relevance of the study. The article deals with the images of Hercules, an old woman and a fly, which take their origins from ancient, Slavic and Eastern mythology.
DEVELOPMENT OF LABIAL CONSONANTS IN TURKIC LANGUAGES
Authors: Khassenov B. R. , Nefedova L. A. , Аdilova A. S.
Published: March 2022

The article examines the archetypal nature of labial consonants in the Turkic languages. In Turkology and Altaic studies, the correspondence of sounds is a well-studied problem. In the question of which of the labial consonants is an archetype, each scientist makes his own assumption. The purpose of this article is to generalize thoughts related to labial consonants and to link the development of labial consonants with speech ontogenesis.
Elevation and construction of covered walkway in Caingin elementary school in the City of Malolos, infrastructure facility improvement: Resulting to better learning environment
Authors: Estacio Madonna R
Published: March 2022

The quality of education infrastructure, specifically its appropriate educational planning and design with a focus on child development, has been widely discussed in recent years. The Sustainable Development Goals, which are defined by the United Nations and scope the development agenda for all countries in the world, require countries to “build and upgrade education facilities that are child, disability and gender sensitive, and provide safe, non-violent, inclusive, and effective learning environments for all.” This study aims to provide Infrastructure Facility Improvement that can be achieved by the Proposed Elevated and Covered Walkway of Caingin Elementary School sought to improve the campus ground to provide a safe and secure environment to all the stake holders. The researcher utilized descriptive research design using combination of qualitative and quantitative methods. The recently raised public road as solution to the recurring problem in the community has impacted directly to the campus of Caingin Elementary School as it turned the ground into catch basin. Urgent and timely action of proposing Infrastructure Facility Improvement through Elevation and Construction of Covered Walkway for comfort, safety and convenience of the stakeholders.
Health Facilities Assessment and Implementation of Facility Based Nutrition Services in Punjab
Authors: Naeem Naureen , Khan M Amjad , Ashraf Aqeela , Hussain Shabbir , Hassan Syeda Mona , Gulzar Fakhar
Published: March 2022

Government of the Punjab provide nutrition services through primary, secondary and tertiary health care facilities across Punjab. But many gaps persist, that reduce the services delivery and timely management of cases, which results in high rate of nutrition maladies. For its appraisal, a rapid assessment of nutrition services centres was conducted, which gauged either these facilities are equipped with standard operating procedures, from identification, treatment and follow up of the patient to service delivery. A rapid assessment tool was developed to measure functionality of these service centres during October-November 2016. The data analysis for the Outpatient Therapeutic Centres (OTP) showed that out of the total number of health facilities samples 73 percent of the centres are fully functional, 24 percent were found to be semi-functional at the time of data collection, largely due to nonavailability of equipment and supplies, while 3 percent of the centres were found to be nonfunctional. Of the 20 Stabilization Centres (SCs) surveyed, one was found to be only semifunctional due to the newly recruited staff, not having received the relevant training details mentioned in the Punjab Nutrition Plan. The SC also did not have available provisions of therapeutic food required to cure malnourished children. The other 19 SCs were reported as fully functional, but it was found that there was weak coordination between some the SC and the Provincial Program Implementation Unit of the program, as they were not sharing their monthly report using the standard reporting format. In order to make nutrition services more functional and effective, proper planning, timely available of medicine, record keeping and follow up are essential components to maintain the integrity of the program.
Importance of Means of Preaching Writing
Authors: Abdulrazzaq Emam
Published: March 2022

All Praise be to Allah Lord of the worlds, and blessings and peace be upon the Imam of the Preachers, the Master of the Prophets, and the Messengers, May Allah be pleased with the Esteemed Companions and the Righteous Followers, and those who followed them with kindness. The aim of the research is to clarify the status of the means of advocacy writing, and to clarify its most prominent characteristics and controls affecting the invitees, deduced from texts. The study established the status of the means of advocacy writing and its elevated status, whose policy was drawn up, inspired by Allah The Almighty, guided the Sunnah of the Prophet, and the Messenger (r) implemented the features of advocacy writing in all fields of da'wah, and the life of the individual, the family, society and the nation. During extrapolation of text of the glorious Quran and purified Sunnah. We find that the preacher gives abundant credit in choosing the best method and the most appropriate in the advocacy writing, in a way that benefits the invitees with good effect and good fruit in both worlds, and it has been shown that the advocacy writing has a high status in the Glorious Quran and purified Sunnah. Therefore, I assumed the supreme place and the high honor in the books of God Almighty. This study made clear that the advocacy writing was distinguished by unique legal characteristics, the severity of these characteristics being linked, and their role in the success of the call.The strength of its influence is according to the effectiveness of the preacher's gain, the accuracy of his mastery and his observance of these characteristics in various fields of the da'wah, and that his keenness and his found, in directing the causes of excellence and creativity in them contributing to the realization of the objectives of the call. In the texts of the Qur’an and Sunnah, it has an important role to devise the provisions of Shari’a, the foundations of the call, its methodology, its means, and methods of persuading the invitees, using eloquent written methods. The origins and branches of science and knowledge, theoretical and applied, and with which all the pillars and origins of the da'wah flourished. And the study has proven that the disciplined advocacy writing, with competence, wisdom, clarity, correctness, priority, and other etiquette, has the greatest impact on the hearts of those invited, the most powerful benefit, reaching their hearts and ears, a fruitful way to persuade and reform their condition, and a practical course for the growth of their scientific and practical strength, and by which it is preserved.
KONTEYNER TAŞIMACILIK İTTİFAKLARI
Authors: ATALAY Murat , AYDIN ÜNAL Duygu
Published: March 2022

Stratejik ittifaklar firmaların mal, hizmet ve teknolojilerinin değiş tokuş, paylaşım ve birlikte geliştirme amacıyla yapmış oldukları gönüllüğe dayalı anlaşmalardır. Denizyolu ittifaklarının faaliyetleri, son on yılda yoğun bir şekilde artmış ve küreselleşmeden kaynaklanan yeni bir ihtiyacı karşılamıştır. Konteyner taşıyıcıların stratejik ittifak kurma amaçlarından en önemlileri; özellikle daha büyük gemileri kullanarak ve birim bazda maliyeti düşürerek ölçek ekonomisinden yararlanma, operasyonel sinerji elde etme, yatay ve dikey bağlamda pazarı kontrol etme, yeni pazarlara girme, müşteri ihtiyaçlarını karşılamaktır. Stratejik ittifakların geliştirilmesi, bu endüstrisi için çok önemlidir. Bu çalışma, deniz taşımacılığı alanında kurulmuş olan stratejik ittifaklarla ilgili araştırmaları sistematik bir biçimde tarayarak analiz etmiştir.
TÜRKİYE’DE TEPE YÖNETİCİLERİN STRATEJİK YÖNETİM SÖYLEMİ
Authors: SÖZÜER Aytuğ
Published: March 2022

Bu çalışmanın amacı, Türkiye’de değişmekte olan iş çevresi ışığında ve tepe yöneticilerin söylemleri vasıtasıyla, ülkedeki stratejik yönetim paradigmasını anlamaktır. Uluslararası değer zincirlerinin bir parçası olan, tam rekabet piyasasına yakın sektörlerde iş yapan veya kamu ihaleleri ve teşviklerin yarattığı fırsatlardan yararlanmak isteyen işletmelerin stratejileri birbirinden ayrışır. Öte yandan, bu işletmeler bulundukları ülkelerin kendine has tarihsel ve kültürel özellikleri ile çeşitli dışsal faktörlerin etkisini sürdürdüğü ortak iş çevresinde yer almaktadır. Bu makro düzen altında, işletmelerin tepe yöneticilerinin söylemleri, ülkede uygulanmakta olan stratejileri de aydınlatabilir. Buradan hareketle, Harvard Business Review Türkiye dergisinde yayınlanmış 73 görüşme içeriği, vurgulanan stratejik yönetim temaları açısından incelenmiştir. Bulgular, işletmelerin eski usul yöneticiliğin ötesinde, modern stratejik yönetim prensiplerine zamanla artan uyumuna işaret etmektedir. Çalışmanın, Türkiye’nin mevcut iktisadi bağlamında işletmecilik anlatısının güncellenmesine katkı sunması beklenmektedir.