bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECT OF A MEDICAL DECOMPRESSION PROTOCOL ON THE USE OF ANTIEMETICS, NASOGASTRIC TUBE USAGE AND DIET ADVANCE IN LATE STAGE CANCER PATIENTS WITH FUNCTIONAL INTESTINAL OBSTRUCTION
Authors: Bhati Anil , Shrivastava Abhishek
Published: December 2020

Background: At the end of life, many cancer patients suffer from a syndrome that simulates classic small bowel obstruction. The traditional approach to intestinal obstruction is relief of pressure in the gastrointestinal tract using mechanical methods. The Medical Decompression(MD) protocol is a non-invasive pharmacologic approach for this problem that is easy and economical.
Methods: The study was done in a academic institution of central India from April 2019 to October 2019. It included 21 cases based on the inclusion and exclusion criteria. Data regarding demographics, cancer diagnosis, existing drug history and diet history was collected and the sample was randomly divided into two groups: one received medical decompression and the other didn’t. The data was compared using t-tests on the outcome variable days to advanced diet.
Results: Out of 21 cases, 43% were males whereas 57% were females with a mean age of 66 years. About 30% of these had a pre-inserted NG tube. Around 19% of these were already on a clear liquid diet. Most men had colon cancer whereas most females had ovarian cancer. A mean of 1.1 doses and 3.8 days was taken to advance the diet. There was a statistically significant difference between the MD and the non MD group.
Conclusions: A pharmacologic method such as MD is strongly useful as first line treatments for the functional intestinal obstruction syndrome and indeed be considered as adjuncts to allow the removal of invasive mechanical interventions in the end of life patient.
A COMPARATIVE ANTICANCER STUDY OF BIOSYNTHESIZED NANOPARTICLES, DOXORUBICIN & NANO-DOX CONJUGATE AGAINST CERVICAL CANCER HELA CELL LINE
Authors: Priya M. R. Kamala , Iyer Priya R.
Published: December 2020

Doxorubicin is the most common chemotherapy drug used in cancer therapy. Its usage is associated with various side-effects. In order to overcome the challenges in Doxorubicin administration, the present study has focussed on synthesizing a drug conjugate with biosynthesized gold nanoparticles and doxorubicin. The gold nanoparticles were biosynthesized using green extracts of medicinal plants with potential anticancer activities. The nanoparticle that possesses anticancer activity was conjugated with the drug for a combinatorial effect of the nanoparticles and the drug. The in vitro cytotoxicity was checked in Vero cell line through MTT assay. The in vitro anti proliferative effects were screened against cervical cancer in HeLa cell line. Fluorescence activated cell sorting analysis was carried out to detect the difference between live and dead cell populations. The preliminary confirmation was carried out in UV-VIS spectrophotometer. The morphological characterization was carried out by SEM and stability by Zeta potential. The IC50 of the nanocompounds demonstrated anti-proliferative activity against cervical cancer similar to the chemotherapeutic drug, Doxorubicin; additionally in a much lesser concentration of the drug. The in vitro cytotoxicity exhibited high viability of cells in Vero cell line with minimum viability of 80% in all the tested concentrations. There was a synergistic effect of the nanoparticles along with the drug; thereby an enhanced therapeutic efficiency was achieved. FACS analysis showed 36% of cell death in Dox treated HeLa cells whereas 96% of cell death in Nano-Dox treated HeLa cells. Nano-Dox conjugate has demonstrated high anticancer effects than drug alone Doxorubicin. Further biosynthesized nanomaterials based drug formulation can be developed as a potential strategy in cancer therapy.
A CASE SERIES OF PLEURO-PULMONARY MANIFESTATIONS IN RHEUMATOID ARTHRITIS PATIENTS AT A TERTIARY CARE HOSPITAL IN KANCHIPURAM
Authors: Banerjee Indranil , Radhika CH. , Srinivasan R.
Published: December 2020

Rheumatoid Arthritis is a systemic inflammatory disorder that most commonly affects the joints, causing progressive, symmetric, erosive destruction of cartilage and bone and is usually associated with autoantibody production. Although joint disease is the main presentation, there are a number of extra-articular manifestations including subcutaneous nodule formation, vasculitis, inflammatory eye disease and lung disease. Of these manifestations, lung disease is a major contributor to morbidity and mortality. There are a variety of pulmonary manifestations of rheumatoid arthritis, including pulmonary parenchymal disease (interstitial lung disease) and inflammation of the pleura (pleural thickening and effusions), airways (bronchiectasis) and pulmonary vasculature (pulmonary hypertension). The present article reports five clinical cases in order to elucidate the diversity of the pathophysiological mechanisms that underlie rheumatoid arthritis associated pulmonary diseases. The five manifestations are: interstitial lung disease, pulmonary hypertension, pleural effusion, bronchiectasis and pulmonary tuberculosis (due to prolonged use of pneumotoxic anti-rheumatoid drugs). This case series illustrates the diagnostic challenges that may occur in pleuro-pulmonary disease associated with RA and also the importance of early diagnosis.
HEMATOLOGICAL PARAMETERS AND MORPHOLOGICALALTERATIONS IN LEUCOCYTES OF COVID-19 PATIENTS
Authors: Murarkar Prashant S , Gosavi Alka Vikas , Jujgar Amruta Shankar , Patil Priyanka Sanjay
Published: December 2020

World Health Organization (WHO) announced COVID-19 outbreak as a pandemic on 11th March 2020. COVID-19 caused its impact globally with a substantial morbidity and mortality in people across the world especially in those at a higher age group with comorbidities. Most of the organ systems are affected including hematopoietic system. We studied the hematological profile of 196 confirmed COVID-19 positive patients at our tertiary care center from 22nd March 2020 to 15th June 2020. Various hematological parameters including Haemoglobin(Hb), Total Leucocyte Count(TLC), Absolute Neutrophil count(ANC), Absolute Lymphocyte Count(ALC), Absolute Monocyte Count(AMC), Absolute Eosinophil Count(AEC), Platelet Count(PC), Neutrophil to Lymphocyte Ratio(NLR), Erythrocyte Sedimentation Rate(ESR) and Peripheral blood smears were studied.
We found Hb levels were decreasing in the patients with more severe disease. Leucopenia, lymphopenia, eosinopenia, neutrophilia, raised ESR and increasing NLR was seen in patients with more severe disease and those who succumbed to death. We also observed various morphological abnormalities in leucocytes in peripheral blood films of these patients. These parameters prove their prognostic significance in risk stratification in the COVID-19 positive patients for early intervention and deciding treatment regimens which may help to alleviate the morbidity and mortality. As these tests are easily available even at low resource settings, in developing country like India this study may help the patients who are being treated at peripheral centers to get referred to a higher center and get better treatment to reduce the morbidity and mortality.
COMPARATIVE STUDY OF CLINICAL VERSUS USG IN DIAGNOSIS OF EARLY TRIMESTER BLEEDING PV
Authors: Hait Narendra Nath , Das Brahmarshi , Mandal Ratan Chandra , Roy Haricharan , Jana Debarshi
Published: December 2020

Background: Threatened abortion is till most common cause of early trimester bleeding PV and can be diagnosed and managed by early USG diagnosis.
Materials and methods: This was a prospective observational study. Place of the study was Department of Obstetrics and Gynaecology and Department of Radiodiagnosis, Midnapore Medical College and Hospital from January 2019 to June 2020. Eighteen months.
Result: When the clinical method to diagnose threatened miscarriage was compared to the sonographic method, it was evident that sonographic method was reliable than the clinical method and the difference was statistically significant.
Conclusion: In case of missed miscarriage and complete miscarriage, although the percentage of discrepancy was 100%, on further statistical analysis, the discrepancy was not statistically significant. And the cause behind this was probably inadequate sampling.
Protocol for a literature review in investigating the potential of DevOps for public sector Information Technology delivery
Authors: Kelly Lesley
Published: December 2020

Background

The United Kingdom (UK) public sector has spent more than
£3.2bn on digital, data and technology services since 2012. The UK public
sector borrowing year ending March 2018 was at £41bn. The debt at the end of
February 2019 was at £1785bn (Office of National Statistics, 2019) and because
of this spiralling debt, the UK government had to implement austerity.
Therefore, there was a need to address solutions to help the government
implement austerity. For example, the NHS Digital (NHSD) annual report and
accounts 2017 to 2018 reported an increase in expenditure for permanent staff,
software development, IT maintenance and IT support. It is evident there is an
increase in expenditure compared to their 2016 to 2017 report. This provides
scope for reduction in expenditure.

Objective

This literature review aims to investigate if DevOps has the
potential to transform public sector IT delivery and provide value for money to
the taxpayer by reducing expenditure in software development, IT maintenance
and IT support. We will also be reviewing the maturity of DevOps in its current
form and address the benefits and downsides from a public sector perspective.

Method

Our literature review will apply the Preferred Reporting
Items for Systematic Reviews and Meta-Analysis Protocol (PRISMA-P). We will
accomplish a two-part study and apply thematic organisation of our literature.
We will use databases recommended by the University of Portsmouth Library. Grey
Literature will be included, but we will exclude untrustworthy literature,
social media, broadcasting, and press media. Only literature with confirmed
validity will be included for further research.
Maximizing the Probability of Message Delivery over Ever-changing Communication Scenarios in Tactical Networks
Authors: Loevenich Johannes , Rigolin F. Lopes Roberto , Rettore Paulo H. , M. Eswarappa Sharath , Sevenich Peter
Published: December 2020

This letter introduces a stochastic model to maximize the probability of message delivery over ever-changing communication scenarios in tactical networks. Our model improves modern tactical systems implementing store-and-forward mechanisms organized in a hierarchy of layers for messages, IP packets and radios. The goal is to compute close to optimal parameters for a transport protocol by computing the optimum redundancy for the user data-flow to overcome packet loss during changes in the link data rate, including disconnections. Experiments in a VHF network illustrate the numerical results from our model using messages with different sizes over two patterns of data rate change.
Los criterios de inclusión-exclusión en el menemismo
Authors: De los Ángeles Yannuzzi Maria
Published: December 2020

Abstract/short description:

Article originally published without abstract
Triunfo y fracaso de ta alternativa revolucionaria en América Central: causas y consecuencias
Authors: Gruszczak Artur
Published: December 2020

Abstract/short description:

The article relates the rise and fall of the revolutionary groups in Central America. Gruszczak states that behind the growth of revolutionary movements in the region, such as those in Guatemala, Salvador, Nicaragua and other Central American countries, were great abuses of civil and human rights. The author notes that the groups, which have been using revolutionary ways, or in other words armed struggle, to achieve their political goals, in 1990's changed their methods of action. Following democratization processes the left-wing militant groups have transformed themselves into political parties, working within the framework of democratic elections.
ARTICLE ON BONAFIDE LEADERSHIP
Authors: Raveen Purohit
Published: December 2020

Bonafide leadership symbolizes one of the most novel spaces of leadership research field. Its focal details lie on assessment regarding leadership. As the approach entails, veritable leadership is about the genuineness of leadership. Dissimilar to the hypothesis that we have talked about in this book, veritable leadership is still in the shaping form of growth. Thus, Bonafide leadership should be regarded as tentative. It is potential to alteration as new research about the hypothesis is issued. Recently, uplifts in order have stimulated enormous requirement for reliable leadership. The catastrophic Covid19 has incorporated outrages in societies plus in the manufacturing, banking, etc. industries. People have become apprehensive and feel unsafe about surrounding and thus, Bonafide leadership finds faith and honesty from people. People need trustworthy leaders thus making the subject of Bonafide leadership well-timed and worthwhile.
Концепция специализированной карты гидроэкологического назначения и основные принципы ее проектирования
Authors: Козелкова Евгения Николаевна , Наговицына Валерия Романовна
Published: December 2020

В статье приводится понятие специализированных карт, основные области применения специализированных карт, концепция специализированной карты гидроэкологического назначения, ее содержание, а также основные принципы ее проектирования.
О культурной жизни эмигрантов первой волны во франции (на примере жизни И.Е. Ачкеева)
Authors: Кадырова Наиля Наилевна
Published: December 2020

В статье затрагиваются вопросы культурной жизни эмигрантов первой волны во Франции. Вопрос рассматривается на основе периодических изданий 1920–30-х гг., выпускавшихся в Париже. Примером насыщенной культурной жизни русской диаспоры во Франции послужила жизнь белоэмигранта И.Е. Ачкеева, проживавшего до 1920 г. в местечке Алексеевский Горячий Ключ. В результате восстановления родословной Ачкеевых жизнь героя Первой Мировой войны Ивана Ачкеева, о котором родственники ничего не знали после 1920 г., была раскрыта до конца его жизни – 1961 года.
Relocating Florence Weiss’ Fieldwork Photography as Anthropological Practice
Authors: Dick Michèle
Published: December 2020

During her 17 months of fieldwork (1972-74) in the village of Palimbei in Papua New Guinea, the Swiss anthropologist Florence Weiss took 5 674 black and white negatives and 4 794 col-our transparencies. Although the photographs were not taken at regular intervals, the average number of approximately 19 photographs per day gives an idea of the presence of photography in her fieldwork practice. Yet, Florence Weiss was not considered – or considered herself – a visual anthropologist. So, what kind of practice does her photography represent, and what role did it play in her wider fieldwork practice?
Attuned to the Everyday
Authors: Loher David , Schwaller Corinne , Wolf Anna-Lena
Published: December 2020

In May 2017, Veena Das joined the second edition of «Anthro-pology Talks» at the University of Bern. Every two years, the Institute of Social Anthropology invites leading social and cultural anthropologists to discuss their recent work. After a series of lectures and workshops, the event concludes with an interview about the visiting scholar’s work and their thoughts on the future of our discipline.
Neue Kaiserweihungen und Ehrungen aus Aspendos
Authors: OKTAN Mehmet , ADAK Mustafa
Published: December 2020

With the start of more recent archaeological research work, several inscriptions were discovered in the central Pamphylian city of Aspendos. This article presents eight of them, mostly copied in the urban area in 2019. The first three inscriptions are imperial dedications, followed by several hono-rary decrees for Roman and local officials. No. 1, whose upper part was already known from a copy by Hirschfeld, contains a dedication for Germanicus Caesar and mentions four priests of emperors and Thea Rome. No. 2 is a public dedication to Hadrian from AD 125. The milestone no. 3, ori-ginally set up about 7.0 km southeast of Aspendos, bears an honorary inscription for Emperor Iu-lian, which overwrites a previous text. No. 4 honours the previously unknown proconsul of the province of Lycia-Pamphylia, Aelius Antonius. Municius Touesianos, the dedicant, held high posi-tions both in Aspendos and in the Pamphylian League. The honorary inscription no. 5 is dated after the well-known equestrian governor Terentius Marcianus, who excelled in fighting a major uprising in AD 278. No. 6 honours the local dignitary Demetrios, priest of the imperial cult for five years, who also served as demiourgos. Here, the long tenure of archiereia seems to be high-lighted as an outstanding achievement. No. 7 honours the physician Zoilos, who served as archiat-ros in his hometown. The last inscription names a C. Curtius (cognomen lost), who was probably related to the senatorial family of the Curtii, known for the foundation of the great theatre.
New Inscriptions from Perge 2: The Funerary Inscriptions of the Tomb Buildings Discovered in Parcel 169 of the Western Necropolis
Authors: ÖZDİZBAY Aşkım
Published: December 2020

This article deals with a second group of funerary inscriptions discovered in the Western Necropolis of Perge during the excavations between 1998 and 2011. The funerary inscriptions in question are located in the excavation site known as Parcel 169. This parcel consists of burial complex M9, tomb building M3 and the burial complex M6 with the burial chamber M6.3. The authors give an architectural description of the monuments with dating suggestions and epigraphic assessments. M9 is the area’s largest, best-preserved, and most monumental burial complex and contains two levels to different periods. It belonged to the local family of the Iulii for over almost a century (from the second half of the 2nd century CE to the second half of the 3rd century CE). The tomb building M3 has a single chamber. Its façade and western side is built of terracotta bricks, while its eastern and southern sides were carved on the natural rock. Inside the tomb are three sarcophagi made of terracotta bricks. Owners of the tomb were Eutychos, his wife and his heirs. The tomb’s architecture points to the 3rd century CE. The tomb complex M6 contains four chambers with the first three constructed with alternating terracotta bricks and mortared rubble stone. M6.3 demonstrates different features from the other burial chambers with its direction, use of limestone blocks for its constructions and its interior design. It belonged to Ophonius Marcianus and was constructed in the 3rd century CE.
Die lykische ?ni mahanahi: griechisch, luwisch oder ,anatolisch'
Authors: SCHÜRR Diether
Published: December 2020

The Lycian designation ẽni mahanahi has no Bronze Age Luwian predecessor, contrary to what is often supposed: This belief is based upon a misunderstanding. There is also no connection between this goddess and the Old Phrygian goddess called matar (kubileya), becoming later the Greek Kybele and the Roman Magna Mater, and the habit of speaking of an ‘Anatolian’ mother goddess is based on a false precondition, because Anatolia (or Asia Minor) was never a linguistic or cultural unity. Ẽni mahanahi could theoretically be a translation of Greek μήτηρ ϑεῶν, ‘mother of the gods’, but if, following mention of Trqqas, the Lycian weather god, in an inscription from Tlos, the words ẽni maha]nahi are to be restored, then an identification with the Greek Leto is still plausible. This goddess is probably attested in Lycia first by the Greek inscriptions of the dynast Erbbina around 400 BC, but may well have been imported significantly earlier.
Zasada jawności a jawność wewnętrzna w procesie karnym
Authors: Koper Radosław
Published: December 2020

Zasada jawności, jako jedna z podstawowych zasad procesu karnego, jest realizowana – z wyjątkami – w toku całego postępowania. Nie jest jednak jednoznaczne, czy ta zasada obejmuje tylko jawność zewnętrzną rozumianą jako dostępność procesu dla społeczeństwa, czy także jawność wewnętrzną. Ten drugi aspekt jawności oznacza głównie dostępność procesu dla stron i ich przedstawicieli. Artykuł został poświęcony problemowi ujętemu w pytaniu: czy zasada jawności obejmuje także jawność wewnętrzną? Przedmiotem opracowania była analiza poglądów doktryny w tym przedmiocie. W konsekwencji autor zaprezentował też własne zapatrywania poparte szeroką argumentacją. Konkluzja artykułu polega na sformułowaniu tezy o potrzebie włączenia jawności wewnętrznej do zakresu zasady jawności.
Zakres znaczeniowy wynagrodzenia w postępowaniu egzekucyjnym w administracji
Authors: Liskowski Mariusz
Published: December 2020

Ustawa – o postępowaniu egzekucyjnym w administracji zawiera legalną definicję terminu „wynagrodzenie”, nadto posługuje się zwrotami „wynagrodzenie ze stosunku pracy”, „egzekucja z wynagrodzenia za pracę”. Mając na względzie powszechne stosowanie przez administracyjne organy egzekucyjne środka egzekucyjnego w postaci wynagrodzenia za pracę, jawi się pytanie, czy ustawa posługuje się wyrażeniem „wynagrodzenie” w tym samym znaczeniu, co w powyższych zwrotach? Artykuł stanowi próbę poszukiwania odpowiedzi na powyższe. W tym celu, w pierwszej kolejności, oś badań odniesiono do ustalenia znaczenia terminu „wynagrodzenie” w ujęciu przepisów ustawy. Dalsze dociekania poświęcono porównawczemu zestawieniu ustalonego znaczenia terminu „wynagrodzenie” ze zwrotami „wynagrodzenie ze stosunku pracy”, „egzekucja z wynagrodzenia za pracę”. Wyznaczone cele determinują zastosowaną metodę badawczą formalno-dogmatyczną, która powinna przyczynić się do udzielenia odpowiedzi na postawione pytanie.
A Digitalisasi Dakwah
Authors: Fairozi Ahmad , Ayu Sulistya
Published: December 2020

Abstrak

Artikel ini membahas tentang upaya meningkatkan daya saing Islam ramah pada masa pandemi. Adanya Covid-19 menuntut seluruh aktivitas dilakukan secara daring, termasuk dakwah. Tulisan ini hendak meneliti daya saing, kompetensi antara kedua dakwah “Islam ramah” dan “Islam marah” pada masa pandemi. Pendekatan deskriptif-analitis dalam teori competitive superiority dan efektivitas dakwah digunakan sebagai alat untuk menganalisis artikel ini. Penelitian ini dilakukan dengan menganalisis konten dakwah dalam situs (Nu.or.id, Panrita.id dan ppanwarulhuda.com) dan channel youtube (164 Chanel dan Tawaf TV), sebagai representasi Islam  ramah. Sementara konten dakwah dalam situs (Hidayatullah.com, Eramuslim.com, dan Voa-islam.com) dan channel youtube (Hidayah.Indonesia dan SAP Chanel) sebagai representasi “Islam  marah”. Tulisan ini menyimpulkan  bahwa dakwah Islam ramah di era pandemi masih lemah sehingga perlu dilakukan optimalisasi. Tulisan ini merekomendasikan digitalisasi dakwah dengan lima langkah yang harus diupayakan; 1) sentralisasi media dakwah, 2) responsif untuk menjadi problem solving, 3) memberi penekanan (emphasize) pada isu penting, 4) framming and authoritative, 5) digital friendly.

Kata Kunci: Digitalisasi dakwah, Daya saing, Islam ramah, Covid-19 

 

Abstract

This article discusses efforts to increase the competitiveness of cordial Islam during the pandemic. The existence of Covid-19 requires all activities to be carried by online, it is including da’wah. This paper intends to examine the competitiveness, the competence between two types of da’wah of “cordial Islam” and “Islamic harsh” during the pandemic. The descriptive-analytical approach in the theory of competitive superiority and the effectiveness of da'wah is used as a tool to analyze this article. This research was conducted by analyzing the da'wah content on websites (Nu.or.id, Panrita.id and ppanwarulhuda.com) and YouTube channels (164 Chanel and Tawaf TV), as representations of cordial Islam. Meanwhile, the da’wah content on the websites (Hidayatullah.com, Eramuslim.com, and Voa-islam.com) and the YouTube channel (Hidayah.Indonesia and SAP Chanel) as a representation of “Islamic harsh”. This paper concludes that cordial Islam da’wah in the pandemic era is still weak, so the optimization needs to be done. This paper recommends digitizing da'wah with five steps that must be pursued; 1) centralization of da’wah media, 2) responsive to be problem solving, 3) emphasizing on ​​crucial issues, 4) framing and authoritative, 5) digital friendly.

Keywords: Digitizing da'wah, Competitiveness, cordial Islam, Covid-19
Associação entre variáveis antropométricas e desempenho esportivo de atletas da seleção masculina de Pentatlo Militar do Exército Brasileiro: um estudo transversal
Authors: Santos Lúcio Luís dos , Mello Danielli Braga de , Sales Thiago Dias , Martins Daniel Tavares de Mattos , Mainenti Miriam Raquel Meira
Published: December 2020

Introdução: O Pentatlo Militar (PMil) é uma modalidade ímpar por possuir características específicas da profissão militar. Identificar o perfil associado ao bom desempenho pode auxiliar na seleção de atletas e na identificação de variáveis importantes para acompanhar a eficácia do treinamento.

Objetivo: Investigar a associação entre variáveis antropométricas e desempenho esportivo em atletas de elite de PMil.

Métodos: Participaram da pesquisa cinco atletas da equipe de PMil masculina do Exército Brasileiro. Calculou-se os componentes da composição corporal: percentual de gordura (%G), massa gorda (MG) e massa livre de gordura (MLG). Foram considerados os melhores resultados de competições oficiais (2017) em análise de Clusters e teste de correlação de Spearman.

Resultados: Houve correlação muito forte positiva de MLG com o desempenho da prova de corrida através-campo (8km) (r=0,90,p=0,04). Não houve correlação significativa com as demais provas da modalidade (tiro, pista de natação utilitária, pista de pentatlo militar e lançamento de granada).

Conclusão: A correlação positiva e muito forte de MLG com o desempenho na prova de corrida indica a destacada relevância desse componente corporal para o desempenho dos pentatletas militares de alto rendimento.
Pre-Transplant Marital Status and Hematopoietic Cell Transplantation Outcomes
Authors: Tay J. , Beattie S. , Bredeson C. , Brazauskas R. , He N. , Ahmed I. A. , Aljurf M. , Askar M. , Atsuta Y. , Badawy S. , Barata A. , Beitinjaneh A. M. , Bhatt N. S. , Buchbinder D. , Cerny J. , Ciurea S. , D’Souza A. , Dalal J. , Farhadfar N. , Freytes C. O. , Ganguly S. , Gergis U. , Gerull S. , Lazarus H. M. , Hahn T. , Hong S. , Inamoto Y. , Khera N. , Kindwall-Keller T. , Kamble R. T. , Knight J. M. , Koleva Y. N. , Kumar A. , Kwok J. , Murthy H. S. , Olsson R. F. , Angel Diaz-Perez M. , Rizzieri D. , Seo S. , Chhabra S. , Schoemans H. , Schouten H. C. , Steinberg A. , Sullivan K. M. , Szer J. , Szwajcer D. , Ulrickson M. L. , Verdonck L. F. , Wirk B. , Wood W. A. , Yared J. A. , Saber W.
Published: December 2020

Background: Evidence about the impact of marital status before hematopoietic cell transplantation (hct) on outcomes after hct is conflicting. Methods: We identified patients 40 years of age and older within the Center for International Blood and Marrow Transplant Research registry who underwent hct between January 2008 and December 2015. Marital status before hct was declared as one of: married or living with a partner, single (never married), separated or divorced, and widowed. We performed a multivariable analysis to determine the association of marital status with outcomes after hct. Results: We identified 10,226 allogeneic and 5714 autologous hct cases with, respectively, a median follow-up of 37 months (range: 1–102 months) and 40 months (range: 1–106 months). No association between marital status and overall survival was observed in either the allogeneic (p = 0.58) or autologous (p = 0.17) setting. However, marital status was associated with grades 2–4 acute graft-versus-host disease (gvhd), p < 0.001, and chronic gvhd, p = 0.04. The risk of grades 2–4 acute gvhd was increased in separated compared with married patients [hazard ratio (hr): 1.13; 95% confidence interval (ci): 1.03 to 1.24], and single patients had a reduced risk of grades 2–4 acute gvhd (hr: 0.87; 95% ci: 0.77 to 0.98). The risk of chronic gvhd was lower in widowed compared with married patients (hr: 0.82; 95% ci: 0.67 to 0.99). Conclusions: Overall survival after hct is not influenced by marital status, but associations were evident between marital status and grades 2–4 acute and chronic gvhd. To better appreciate the effects of marital status and social support, future research should consider using validated scales to measure social support and patient and caregiver reports of caregiver commitment, and to assess health-related quality of life together with health care utilization.
Presenting Stage and Risk Group in Men Dying of Prostate Cancer
Authors: Parimi S. , Bondy S. , Aparicio M. , Sunderland K. , Cho J. , Bachand F. , Chi K. Nguyen , Pickles T. , Tyldesley S.
Published: December 2020

Introduction: Prostate cancer remains the 3rd leading cause of cancer-related mortality in Canadian men, and yet screening for prostate cancer continues to be controversial because the majority of men diagnosed with prostate cancer do not die of the disease. It also remains uncertain whether treatment of cases that can be treated with curative intent alters the mortality rate. There are very few studies describing the presenting stage, risk groups, and survival after diagnosis for men dying of prostate cancer in the literature. In this study, we explored these characteristics for all men who died of prostate cancer in British Columbia between 2013 and 2015. Methods: The population-based BC Cancer databases were used to identify all patients diagnosed between January 2013 and December 2015 who died of prostate cancer. Patient, tumour, and treatment characteristics were collected, and the risk grouping for each tumour was determined. The proportion of cases in each risk group at the time of diagnosis was determined. Survival time from diagnosis to death was calculated for all patients and for each risk group using the Kaplan–Meier method. Results: A total of 1256 patients died of prostate cancer. Of patients who presented with metastatic disease, 57.2% presented with a Gleason score of 8 or more, compared with only 35.7% of patients who presented with nonmetastatic disease (p < 0.0001). The presenting stage and risk group of those dying of prostate cancer were as follows: 32% metastatic disease, 3% regional (defined as node-positive), 39% localized high risk, 9% localized intermediate risk, 4% localized low risk, 6% localized not otherwise specified, and 7% unknown. Therefore, 80.3% of those with a known risk group presented with either localized high-risk, regional, or metastatic disease at diagnosis. The median survival times from diagnosis to death were 12 years for localized low-risk, 10 years for localized intermediate-risk, 6.5 years for localized high-risk, 4 years for regional, and 1.7 years for metastatic disease at diagnosis. Conclusions: This population-based analysis demonstrates that patients with localized high-risk, regional, or metastatic disease at diagnosis constitute the overwhelming majority of patients who die of prostate cancer in British Columbia. Unless these disease states can reliably be identified at an earlier low- or intermediate-risk localized state in the future, it is unlikely that treatment of localized low- and intermediate-risk cancer will have an impact on survival. Furthermore, patients with de novo metastatic disease had identifiable risk factors of a higher prostate-specific antigen and Gleason score. Further studies are required to confirm these results.
Canadian Guidelines on the Management of Colorectal Peritoneal Metastases
Authors: Brind’Amour A. , Dubé P. , Tremblay J.F. , Soucisse M.L. , Mack L. , Bouchard-Fortier A. , McCart J.A. , Govindarajan A. , Bischof D. , Haase E. , Giacomantonio C. , Hebbard P. , Younan R. , MacNeill A , Boulanger-Gobeil C. , Sidéris Lucas
Published: December 2020

Modern management of colorectal cancer (CRC) with peritoneal metastasis (PM) is based on a combination of cytoreductive surgery (CRS), systemic chemotherapy, and hyperthermic intraperitoneal chemotherapy (HIPEC). Although the role of hipec has recently been questioned with respect to results from the PRODIGE 7 trial, the role and benefit of a complete CRS were confirmed, as observed with a 41-month gain in median survival in that study, and 15% of patients remaining disease-free at 5 years. Still, CRC with PM is associated with a poor prognosis, and good patient selection is essential. Many questions about the optimal management approach for such patients remain, but all patients with PM from CRC should be referred to, or discussed with, a PM surgical oncologist, because cure is possible. The objective of the present guideline is to offer a practical approach to the management of PM from CRC and to reflect on the new practice standards set by recent publications on the topic.
Národní muzeum pohledem Československé televize ve druhé polovině 20. století
Authors: Hadaš Jiří
Published: December 2020

Based on historiographical procedures and methods used in the field of media science, a research was conducted, through quantitative and qualitative analysis, on unique historical sources in the form of television programs which provided information on the National Museum. In the selected period, which is delimited by the year 1953, when television broadcasting began in Czechoslovakia and the year 1993, an analysis of these media was undertaken focusing on their use as historical sources. In the period under review, a genre diversity was detected, which offered news service, opinion journalism, educational programs and entertainment. Through historical sources, valuable in today’s perspective, these programs formed the media image of the National Museum as an institution with a rich past closely linked to national history and as an irreplaceable scientific platform.
Using Data Mining In Learning Management Systems Amidst Covid-19
Authors: Mobo Froilan D
Published: December 2020

The Second Semester of Academic Year 2019-2020 was temporarily suspended due to the widespread COVID-19 last March 16, 2020, forcing the President of the Republic of the Philippines, Hon. Rodrigo Roa Duterte imposed an Enhanced Community Quarantine in Luzon which is known as a lockdown closing all the border points of each town and provinces. One of the major problem encountered during the lockdown is the suspension of classes because as per IATF guidelines you need to stay home, the said Memorandum Order was posted in the official gazette, (Medialdea, 2020)

The dataset on the features of the Learning Management Systems using Moodle is that Professors will be the one who will set the topics, quizzes, and exercises for his class even the assessment methods on the system. To prevent from slowing down the network,  the Team of Seaversity the developer of the learning management systems headed by C/E Ephrem Dela Cernan conducts a ZOOM Training to all Faculty to be familiarized more on the Learning Management Systems of the Philippine Merchant Marine Academy. 

The Moodle Learning Management Systems is a user-friendly environment because of its features and users can easily adjust from the traditional face to face teaching going to e-Learning approach because of it’s all capabilities as a data mining methods such as statistics, association rule mining, pattern mining visualization, categorization, clustering, and text mining., (AlAjmi & Shakir, 2013)
Analisis Terapi Komplementer Yoga Terhadap Penyalahgunaan Napza Pada Remaja
Authors: Indirawaty Indirawaty , Syarif Kurnia Rahma , Genggeng Rosita , Sumirah Sumirah
Published: December 2020

According to Riskesdes data (2018), the prevalence of mental disorders has increased when compared to the 2013 Riskesdes from 1.7% to 7%. In addition, the prevalence of mental emotional disorders in people aged> 15 years rose from 6% to 9.8%. Based on the results of data analysis the World Drug Report states that in this decade showed about 208 million people or 5% of the world's population who use narcotics and other addictive substances. Users of narcotics, psychotropic substances and other addictive substances are aged 15 years to 64 years and it is estimated that in 2025 it will increase to 15% of the world's population (Syahrial, 2015). One method that can be used to help control depression or mood due to narcotics consumption is complementary yoga therapy (Streeter, Gerbarg, Domenic, & Brown, 2012). The research design used was quasy experimental. In this study, One group pretest posttest design. The subjects in this study were 40 people with kiteria. The results of the study are based on paired t test results obtained that the value of the statistical test results obtained p value (0,000) <0.05 which means there is a difference in knowledge scores between before and after the intervention while the statistical test results obtained p value (0,000) <0.05 which means there is a difference in scores attitude between before and after the intervention. So it can be concluded that complementary yoga therapy can increase knowledge and attitudes on drug abuse.
Construction of Optimal Investment Portfolio Based on Efficient Portfolios Complex
Authors: Gertsekovich David
Published: December 2020

The paper presents the scheme for preliminary processing of historical records, provides the algorithm for historical sample length optimization, estimates expected returns and risks by prognostic models of optimal complexity, drawing on the principle of integrated decisions. The author offers a new method to generate efficient portfolios taking into account cross correlation links and construction of investment portfolio of optimal complexity based on the principle of integrated decisions.
The Blue Straggler Population of the Open Clusters Trumpler 5, Trumpler 20, and NGC 2477
Authors: Rain M. J. , Carraro G. , Ahumada J. A. , Villanova S. , Boffin H. , Monaco L.
Published: December 2020

We present a study based on Gaia DR2 of the population of blue straggler stars in the open clusters Trumpler 5, Trumpler 20, and NGC 2477. All candidates were selected according to their position in the color–magnitude diagram, their proper motion components, and their parallax. We also looked for yellow stragglers, i.e., possible evolved blue stragglers. We found that Trumpler 5 hosts a large blue straggler star population, which allowed us to analyze their radial distribution as a probe of the cluster’s dynamical status. The blue straggler star distribution was compared with that of red giant branch stars to evaluate mass segregation. Our results indicate that blue straggler stars are not more centrally concentrated than red giant branch stars stars in any of the clusters. The radial distribution of blue straggler stars in Trumpler 5 is flat. Additionally, using a multi-epoch radial velocity survey conducted with the high-resolution spectrograph FLAMES/GIRAFFE at the Very Large Telescope, we measured the radial velocities of a sample of stragglers to compare with the mean radial velocity and velocity dispersion of the clusters. Based on the radial velocity variations for different epochs, we roughly classified these stars as possible close or long-period binaries.
ARMADA. I. Triple Companions Detected in B-type Binaries α Del and ν Gem
Authors: Gardner Tyler , Monnier John D. , Fekel Francis C. , Schaefer Gail , Johnson Keith J. C. , Le Bouquin Jean-Baptiste , Kraus Stefan , Anugu Narsireddy , Setterholm Benjamin R. , Labdon Aaron , Davies Claire L. , Lanthermann Cyprien , Ennis Jacob , Ireland Michael , Kratter Kaitlin M. , Ten Brummelaar Theo , Sturmann Judit , Sturmann Laszlo , Farrington Chris , Gies Douglas R. , Klement Robert , Adams Fred C.
Published: December 2020

Ground-based optical long-baseline interferometry has the power to measure the orbits of close binary systems at ∼10 μas precision. This precision makes it possible to detect “wobbles” in the binary motion due to the gravitational pull from additional short-period companions. We started the ARrangement for Micro-Arcsecond Differential Astrometry (ARMADA) survey with the Michigan Infra-Red Combiner (MIRC)/MIRC-X instrument at the Center for High Angular Resoloution Astronomy (CHARA) array for the purpose of detecting giant planets and stellar companions orbiting individual stars in binary systems. We describe our observations for the survey, and introduce the wavelength calibration scheme that delivers precision at the tens of microarcseconds level for <02 binaries. We test our instrument performance on a known triple system, κ Peg, and show that our survey is delivering a factor of 10 better precision than previous similar surveys. We present astrometric detections of tertiary components to two B-type binaries: a 30 day companion to α Del, and a 50 day companion to ν Gem. We also collected radial velocity data for α Del with the Tennessee State University Automated Spectroscopic Telescope at Fairborn Observatory. We are able to measure the orbits and masses of all three components in these systems. We find that the previously published radial velocity orbit for the inner pair of ν Gem is not consistent with our visual orbit. The precision achieved for these orbits suggests that our ARMADA survey will be successful at discovering new compact triple systems to A/B-type binary systems, leading to better statistics of hierarchical system architectures and formation history.
Role of the Fan Beam Model in Population Synthesis of Isolated Radio Pulsars
Authors: Huang W. J. , Wang H. G.
Published: December 2020

On the basis of the P
sr
P
op
P
y software package, we developed an evolution model of population synthesis for isolated radio pulsars by incorporating the fan beam model, an alternative radio emission beam model to the widely used conal beam model. With proper choice of related models and parameters, we successfully reproduced the observational distributions of Galactic longitude (l) and latitude (b), spin period, period derivative, dispersion measure and 1.4 GHz flux density for the 1214 isolated pulsars discovered by the Parkes multibeam and Swinburne pulsar surveys. The size of the underlying population of radio-loud pulsars is found to be 2.27 × 106, which is larger than the underlying population of radio-loud pulsars simulated with the conal beam model. The model is used to estimate the number of isolated radio pulsars detected by the Galactic-plane pulsar survey with Five hundred-meter Aperture Spherical Telescope (FAST). Approximately 2700 and 240 new isolated pulsars are expected to be discovered in the inner galactic plane (20° < l < 90°, ∣b∣ < 10°) and the outer galactic plane (150° < l < 210°, ∣b∣ < 10°), respectively. These numbers are smaller than those estimated by the evolution models with conal beams and the snapshot models.
Coherent Events at Ion Scales in the Inner Heliosphere: Parker Solar Probe Observations during the First Encounter
Authors: Perrone Denise , Bruno Roberto , D’Amicis Raffaella , Telloni Daniele , Marco Rossana De , Stangalini Marco , Perri Silvia , Pezzi Oreste , Alexandrova Olga , Bale Stuart D.
Published: December 2020

The Parker Solar Probe mission has shown the ubiquitous presence of strong magnetic field deflections, namely switchbacks, during its first perihelion where it was embedded in a highly Alfvénic slow stream. Here, we study the turbulent magnetic fluctuations around ion scales in three intervals characterized by a different switchback activity, identified by the behavior of the magnetic field radial component, B

r
. Quiet (B

r
does not show significant fluctuations), weakly disturbed (B

r
has strong fluctuations but no reversals), and highly disturbed (B

r
has full reversals) periods also show different behavior for ion quantities. However, the spectral analysis shows that each stream is characterized by the typical Kolmogorov/Kraichnan power law in the inertial range, followed by a break around the characteristic ion scales. This frequency range is characterized by strong intermittent activity, with the presence of noncompressive coherent events, such as current sheets, vortex-like structures, and wave packets identified as ion cyclotron modes. Although all these events have been detected in the three periods, they have different influences in each of them. Current sheets are dominant in the highly disturbed period, wave packets are the most common in the quiet interval; while, in the weakly disturbed period, a mixture of vortices and wave packets is observed. This work provides an insight into the heating problem in collisionless plasmas, fitting in the context of the new solar missions, and, especially for Solar Orbiter, which will allow an accurate magnetic connectivity analysis to link the presence of different intermittent events to the source region.
A Model for Coronal Inflows and In/Out Pairs
Authors: Lynch Benjamin J.
Published: December 2020

This report presents a three-dimensional (3D) numerical magnetohydrodynamics (MHD) model of the white-light coronagraph observational phenomena known as coronal inflows and in/out pairs. Coronal inflows in the Large Angle and Spectrometric Coronagraph/C2 field of view (approximately

) were thought to arise from the dynamic and intermittent release of solar wind plasma associated with the helmet streamer belt as the counterpart to outward-propagating streamer blobs, formed by magnetic reconnection. This interpretation was essentially confirmed with the subsequent identification of in/out pairs and the multispacecraft observations of their 3D structure. The MHD simulation results show relatively narrow lanes of density depletion form high in the corona and propagate inward with sinuous motion that has been characterized as “tadpole-like” in coronagraph imagery. The height–time evolution and velocity profiles of the simulation inflows and in/out pairs are compared to their corresponding observations and a detailed analysis of the underlying magnetic field structure associated with the synthetic white-light and mass density evolution is presented. Understanding the physical origin of this structured component of the slow solar wind’s intrinsic variability could make a significant contribution to solar wind modeling and the interpretation of remote and in situ observations from Parker Solar Probe and Solar Orbiter.
A Herschel Mapping of
, and
Lines from the Circumnuclear Region of M31
Authors: Li Zongnan , Li Zhiyuan , Smith Matthew W. L. , Gao Yu
Published: December 2020

The circumnuclear region of M31, consisting of multiphase interstellar media, provides a close-up view of the interaction of the central supermassive black hole and surrounding materials. Far-infrared (FIR) fine-structure lines and their flux ratios can be used as diagnostics of physical properties of the neutral gas in this region. Here we present the first FIR spectroscopic mapping of the circumnuclear region of M31 in [C ii] 158 μm, [O i] 63 μm, and [O iii] 88 μm lines with the Herschel Space Observatory, covering an ∼500 × 500 pc (2′ × 2′) field. Significant emissions of all three lines are detected along the so-called nuclear spiral across the central kiloparsec of M31. The velocity field under a spatial resolution of ∼50 pc of the three lines are broadly consistent and also consistent with previous CO(3–2) line observations in the central region. Combined with existing [C ii] and CO(3–2) observations of five other fields targeting the disk, we derived the radial distribution of [C ii]/CO(3–2) flux ratio, and found that this ratio is higher in the center than in the disk, indicating a low gas density and strong radiation field in the central region. We also found that the [C ii]/FIR ratio in the central region is 5.4 (±0.8) × 10−3, which exhibits an increasing trend with the galactocentric radius, suggesting an increasing contribution from the old stellar population to dust heating toward the center.