bluuebunny/crossref_metadata_2025 huggingface dataset:
Oxidative Transformation of Nafion-Related Fluorinated Ether Sulfonates: Comparison with Legacy PFAS Structures and Opportunities of Acidic Persulfate Digestion for PFAS Precursor Analysis
Authors: LIU ZEKUN , Jin Bosen , Liu Tianchi , Gao JInyu , Men Yujie , Liu Jinyong
Published: January 2024

The total oxidizable precursor (TOP) assay has been extensively used for detecting PFAS pollutants without analytical standards. It uses hydroxyl radical (HO•) from the heat-activation of persulfate under alkaline pH to convert H-containing precursors to perfluorocarboxylates (PFCAs) for target analysis. However, the current TOP assay oxidation method does not apply to emerging PFAS because (i) many structures do not contain C−H bonds for HO• attack, and (ii) the transformation products are not necessarily PFCAs. In this study, we explored the use of classic acidic persulfate digestion, which generates sulfate radical (SO4−•), to extend the capability of TOP assay. We examined the oxidation of Nafion-related ether sulfonates that contain C−H or −COO−, characterized the oxidation products, and quantified the F atom balance. The SO4−• oxidation greatly expanded the scope of oxidizable precursors. The transformation was initiated by decarboxylation, followed by various spontaneous steps such as HF elimination and ester hydrolysis. We further compared the oxidation of legacy fluorotelomers using SO4−• versus HO•. The results suggest novel product distribution patterns depending on the functional group and oxidant dose. Therefore, (1) the combined use of SO4−• and HO• oxidation, (2) the expanded list of standard chemicals, and (3) further elucidation of SO4−• oxidation mechanisms will provide more critical information to probe PFAS precursor structures.
Poly(L-glutamic acid) augments the transfection performance of lipophilic polycations by overcoming tradeoffs among cytotoxicity, pDNA delivery efficiency, and serum stability
Authors: Sekar Ram Prasad , Lawson Jessica L. , Wright Aryelle R.E. , McGrath Caleb , Schadeck Cesar , Kumar Praveen , Tay Jian , Dragovan Joseph , Kumar Ramya
Published: January 2024

Polycations are scalable and affordable nanocarriers for delivering therapeutic nucleic acids. Yet, cationicity-dependent tradeoffs between nucleic acid delivery efficiency, cytotoxicity, and serum stability hinder clinical translation. Typically, the most efficient polycationic vehicles also tend to be the most toxic. For lipophilic polycations—which recruit hydrophobic interactions in addition to electrostatic interactions to bind and deliver nucleic acids—extensive chemical or architectural modifications sometimes fail to resolve intractable toxicity-efficiency tradeoffs. Here, we demonstrate a facile post-synthetic polyplex surface modification strategy wherein with poly(L-glutamic acid) (PGA) rescues toxicity, inhibits hemolysis, and prevents serum inhibition of lipophilic polycation-mediated plasmid (pDNA) delivery. Importantly, the sequence in which polycations, pDNA, and PGA are combined dictates pDNA conformations and spatial distribution. Circular dichroism spectroscopy reveals that PGA must be added last to polyplexes assembled from lipophilic polycations and pDNA; else, PGA will disrupt polycation-mediated pDNA condensation. Although PGA did not mitigate toxicity caused by hydrophilic PEI-based polycations, PGA tripled the population of transfected viable cells for lipophilic polycations. Non-specific adsorption of serum proteins abrogated pDNA delivery mediated by lipophilic polycations; however, PGA-coated polyplexes proved more serum-tolerant than uncoated polyplexes. Despite lower cellular uptake than uncoated polyplexes, PGA-coated polyplexes were imported into nuclei at higher rates. PGA also silenced the hemolytic activity of lipophilic polycations. Our work provides fundamental insights into how polyanionic coatings transform intermolecular interactions between lipophilic polycations, nucleic acids, and serum proteins, and facilitate gentle yet efficient transgene delivery.
Nuclear Quantum Effects in Gas-Phase Ethylene Glycol
Authors: Arandhara Mrinal , Ramesh Sai
Published: January 2024

Path integral molecular simulations are used to explore the nuclear quantum effects (NQEs) on the structure, dihedral landscape and infrared spectrum of ethylene glycol. The simulations are carried out on a new reaction surface Hamiltonian-based model potential energy surface, with especial focus on the role of the OCCO and HOCC dihedrals. By contrast with classical simulations, we analyse how the intramolecular interaction between the OH groups changes due to zero-point effects as well as temperature. These are found to be weak. The NQEs on the free energy profile along the OCCO dihedral are analysed, where notable effects are seen at low temperatures and found to be correlated with the radii of gyration of the atoms. Finally, the power spectrum of the molecule from path integral simulations is compared with the experimental infrared spectrum, yielding good agreement of band positions.
Numerical representations of AB-type copolymer complexes: Analysis of 1H NMR chemical shift patterns in terms of a Smith-Cantor set
Authors: Colquhoun Howard , Grau-Crespo Ricardo
Published: January 2024

When considering the possibility of storing information in the sequence of monomer residues within an AB-type copolymer chain, it is constructive to model that sequence as a string of ones and zeros. The local (intramolecular) environment around a given monomer residue within the chain can then be represented by another string of integers, which we denote as a code, obtained by summing pairs of digits at equivalent positions, in both directions, from that monomer residue’s position. The code can include only the integers 0, 1 and 2, and in principle it can represent a number in any base b, higher than 2 (i.e. it cannot be a binary number). Whereas in base b = 3 the resulting set of codes includes all numbers (because only digits 0, 1 and 2 are required for ternary representations), in any base b > 3 the codes define a limited set of numbers comprising a type of fractal we term a last-fraction Smith-Cantor set. Experimentally, the 1H NMR spectrum of a random, AB-type co(polyester-imide) shows, on complexation with the ring-current-shielding molecule pyrene, a pattern of chemical shifts approximating very closely to the fourth-quarter Smith-Cantor set (i.e. b = 4). It is demonstrated that this pattern results from the binding of pyrene to single diimide residues under conditions of fast-exchange on the NMR timescale. Other co(polyimide) complexes show a related 1H NMR pattern, but one now corresponding to a specific sub-set of the same fractal. We show that this sub-set corresponds to codes based on a “stop-at-zero” limitation, whereby digits in the initial string are disregarded (i.e. set to zero) for code-generating purposes if they occur beyond a zero, when viewed from the central “1”. This limitation is found to arise in copolymer systems where the shielding molecule binds by intercalation between pairs of adjacent diimide residues. The present numerical approach provides a complete, unifying theory to account for the emergence of fractal character in the 1H NMR spectra of AB-type copolymer complexes.
A Research on Clinical Pharmacists' Assessment of Drug-Related Problems in Patients with Chronic Kidney Disease
Authors: Chakra R Gautham , Kumar Reddy K. Venkata Lava , Dilshad K. , Thulasi P. , Taj S. Shereen , Vasantha S. , Lathifmunnisha Y. , Akshitha P. , Jayasree M.
Published: January 2024

The aim of the study is to Spirulina protective effects against acute Fenitrothion-induced toxicity in rats. The objective of a present investigation has been to determine if Spirulina could protect male Wistar albino rats from the toxic effects of Fenitrothion by acting as an antioxidant and hepato-nephroprotector. The toxic effects of DLM are significantly influenced by oxidative stress. In numerous earlier interventions, antioxidants are useful in reducing DLM-induced toxicity. Spirulina is a strong antioxidant that has the potential to lessen the effects of numerous common chemotherapeutic drugs and insecticides. It is evident from the current study that DLM exposure caused variable changes in serum biochemical indicators, levels of lipid peroxidation, and the inhibition of antioxidant enzyme activity. In terms of biochemical changes in blood and tissues, antioxidant enzyme activity, and oxidative stress, AP pre-exposure offered almost full protection.
Optimum Duration for Efficient Gait Training in New Transtibial Prosthesis Users
Authors: Balaji G Enian , Sharma Minakshi
Published: January 2024

Background Gait training is the key to regain the ability to walk independently following amputation. There are many gait training methods with different durations for lower limb amputation LLA. ICRC gait training was the most common type used over ground training method for LLA. Researchers found a gap in the studies regarding the appropriate duration of gait training. Aim To determine the optimum prosthetic gait training duration for the new transtibial users with regard to stability balance speed and mobility.Methods A total of 16 patients eight each in group 1 and group 2 continued with prosthetic training. After completing the same gait training with different durations 40 mins20 mins for seven days outcome measures were taken and analysed. Results The scores of Berg Balance Scale BBS were 48.50 plusmn 2.83 SD3.46 in group 1 and 53.50 plusmn 3.33 SD0.92 in group 2 P lt0.004. Four-Square Step Test FSST of 11.75 plusmn 2.23 s SD2.29 in group 1 and 9.03 plusmn 1.28 s SD1.28 in group 2 P lt0.001 L test 27.61 plusmn 2.83 SD2.82 in group 1 20 mins and 22.24 plusmn 3.33 SD3.32 in group 2 40 mins P lt0.011 and 10 meter walk test 10MWT 8.92 plusmn 2.3 s SD2.99 in group 1 and 5.78 plusmn 0.35 s SD0.34 in group 2 P lt0.011 were noted.Conclusion The gait duration of 40 minutes was effective in improving stability mobility speed and balance. The results of this study demonstrated significant impact of gait training durations of 20 mins and 40 mins in improving stability mobility balance and speed.
An Overview of Rasa Chandamshu / Rasa Ratna Sangraha: A 20th Century Contribution in Rasashastra
Authors: Kumar Shashi , Jadar Prashant , Metia Elina
Published: January 2024

Rasa Chandamshu 20th century C.E. alchemical treatise authored by Shri Datta Vaidya is a useful compilation book related to preparation of medicines of mineral and metallic origin. The present work is an attempt to study and summarize the important comprehensive and specific points mentioned in Rasa Chandamshu and to elaborate the contribution of Rasa Chandamshu.This text throws light on the state of Indian expertise in the field of alchemy regarding the extraction purification conversion of metals minerals into therapeutically suitable forms various instruments developed for alchemical purposes and treatment of numerous diseases by using herbo-mineral preparations. The uses of metals and minerals in treating nearly about 87 diseases are explained in this text with their pathophysiology symptomatology and therapeutics. This book gives detailed description of about 700 formulations.Practical aspect dealt regarding the processing of various Rasaushadhi makes the text unique in its presentation and utility. Classifications of minerals and metals description of some new instruments are the key features of Rasa Chandamshu.
Development of Shodashanga Data Template: A Discrete Template to Accomplish Manuscript Literature Studies in Ayurveda
Authors: Kumar Arhanth , . Shreevathsa
Published: January 2024

Literature is the paramount strength of Ayurveda. Huge literary data are available in manuscript centres across India and overseas. Meanwhile Ministry of AYUSH CCRAS Ministry of Culture and other funding agencies are motivating Ayurveda research scholars to review and research on extensive Ayurveda manuscripts. During this significant time concerned personnel should be prepared with vital requisites in terms of expertise tools advancements etc. As of now there is no proven or standard guidelines to perform literary research on Ayurveda manuscripts. Many scholars who are well versed or exposed to Ayurveda manuscripts follow their own methodology. These methodologies may not be applicable for all Ayurveda manuscript research projects. Hence there is a need for standard protocol development. Shodashanga data template is a distinctive template developed exclusively for Ayurveda manuscript studies. Here criteria are set mainly based on 16 specialities of Ayurveda followed by critical analysis aspects under different headings. Contents of any Ayurveda manuscript can be collected and arranged based on this Shodashanga data template. Based on the entry in the template even critical analysis of many manuscripts can be done simultaneously. Altogether Shodashanga data template is an effective tool to perform manuscript literature studies in a reasonably effective way in Ayurveda fraternity.nbsp
Evaluation of Effectiveness of Mineral Trioxide Aggregate for Root Furcation Repair Using Diode Laser as Adjunct - An In Vitro Study
Authors: Rahul S Halkai , Amaan Ahmed , Kiran R Halkai
Published: January 2024

Background Most of the materials used for furcation perforation repair often leads to microleakage. Therefore novel techniques to prevent this are needed. This study aimed to determine the ability of Mineral trioxide aggregate MTA and Ethoxy benzoic acid Super EBA along with laser for sealing the root furcation.Methods About 108 human-extracted mandibular molar teeth were decoronated at directly above and beneath the furcal area. After access opening the canal orifices were closed with sticky wax. A furcal defect of 1 mm width was prepared. The specimens were allocated into six groups for furcation repair n18. Group 1 MTA Group 2 Super EBA Group 3 Laser MTA Group 4 Laser Super EBA Group 5 positive control Unrepaired furcal defect and Group 6 negative control Intact furcation. In Groups 3 and 4 furcal defects were irradiated with diode 980 nm laser before placing the materials. All specimens were submerged in 2 methylene blue solution for two days were cleaned with sterile water and sectioned mesiodistally. Microleakage was assessed using stereomicroscope. Data was analysed using SPSS version 22. One-way ANOVA and Post hoc Tukey tests were used P le0.05.Results Except for the MTALaser all groups demonstrated decreased microleakage which was statistically significant. The positive control group showed highest microleakage and the negative control group showed none.Conclusion MTA as adjunct to laser activation is effective in preventing microleakage in furcation defects.nbsp
The Use of a Silk Fibroin-Based Dressing on Full Thickness Facial Skin Wounds: A Randomised Controlled Clinical Trial
Authors: NK Aditya , Lakshmi Shubha
Published: January 2024

Background and Objectives Trauma and surgical procedures often produce open wounds on the facial skin. These wounds need to be covered by a dressing or graft to prevent microbial infection excessive fluid loss contamination and optimize the rate of wound healing. Aesthetics and minimal contracture are added concerns for wounds on the face. Silk Fibroin SF membranes containing Asiaticoside membrane was used as dressing in full-thickness facial wounds and its effectiveness as a biological dressing material was evaluated.Methods Twenty four consenting adults were chosen for the study and randomly allotted to SF or petrolatum Gauze PG groups. The dressings were assessed based on the parameters of wound surface area pain relief granulation and epithelisation of the wound exudate produced adherence frequency of change and total scores. Scoring was done on the day of enrolment and over the four subsequent weeks and the performance of the dressing membranes was evaluated.Results SF membrane showed significantly higher scores in the formation of granulation tissue epithelisation exudation and frequency of dressing change. No inflammatory or allergic reaction to the SF membrane was recorded. Significantly higher total scores were seen in the SF membrane group.Conclusion Higher total scores indicated the effectiveness of SF membrane as a dressing in extraoral open wounds compared to PG. The SF membrane was found to be a safe and biocompatible wound dressing material.
Comparative Evaluation of Disinfection of Dental Water Unit Line Using Neem Extract and Sodium Hypochlorite: An In vitro Study
Authors: Monteiro Nikhil , P Shetty Prashant , Ashwini Vergis Bettina , Madhavan Souparna , Varma Lavanya
Published: January 2024

Background Dental Unit Water Lines DWU disinfection is important because of the risk of infection via aerosol to dental staff and patients particularly to those with comorbidities. Objectives To quantify microorganisms in dental water unit line prior to disinfection and to determine the effectiveness of Neem extract and Sodium hypochlorite in reducing the microbial count.Methods 50 mL of water samples were collected in sterile containers from the outlets of airwater syringe and high-speed hand piece of 20 dental chairs and the contamination of microorganisms in DWU total viable count were estimated. The samples were subjected to serial dilutions were inoculated onto R2A agar plates and the colony forming unitsmL were manually counted. The dental water unit lines were treated with either 5 Sodium hypochlorite or commercially available Neem extract after obtaining the baseline samples. Water samples were collected after 48 hours and were quantified again for total viable count. SPSS version 23 was used to analyse the data. Paired and unpaired ldquotrdquo tests were applied to analyse the data before and after the intervention.Results The difference between the two groups at baseline P gt0.05 was not statistically significant. In Group 1 Neem group the mean CFUmL at baseline was 128.70 and after the intervention it reduced to 51.90. In Group 2 Sodium hypochlorite group the mean CFUmL at baseline was 125.90 28.661 and after intervention it reduced to 0 both were found statistically significant P lt0.05.Conclusion Sodium hypochlorite was found to be significantly effective compared to Neem extract in disinfecting DUWL system.nbsp
Analyzing Susceptibility and Severity of SARS-CoV-2 Virus with ABO Blood Group Type
Authors: A Mehta Mahima , S Renuga , NS Sahana , G Suganya , T Yadav Satish , J Chandrakala
Published: January 2024

Background The Corona virus spread like a wild fire and took millions of lives worldwide. New variants with new symptoms are evolving periodically. The complete understanding of virus and its virulence is much needed to save lives. The present study on susceptibility and severity of Corona virus among the individuals belonging to various blood groups will help in better understanding of this deadly infection.Aim To study the susceptibility and severity of COVID infection among the previously COVID infected individuals belonging to different blood groups.Method This was an online questionnaire survey which included 353 COVID infected individuals. The questionnaire was prepared in Google forms based on the required data and was circulated on various social media platforms. Results A significant difference was noted among the individuals of various blood groups with respect to COVID symptoms especially diarrhoea frequency of COVID infection mode of treatment breathlessness among the hospitalized individuals post COVID complications and speed of recovery.Conclusion Elaborate studies on susceptibility and severity of infection among various blood groups may serve as an efficient biomarker and also effective tool for triaging the high-risk groups. This would further help to take precautionary steps in treating individuals belonging to more susceptible blood groups.
Modern Endodontic Rotary File Systems - A Review
Authors: Aishwarya K Sneha , Prasad BS Keshava
Published: January 2024

Endodontic treatment approaches have advanced dramatically in recent decades due to the introduction of various novel techniques and devices. Clinicians should be versed in all the properties and capabilities of the devices that can be utilised to perform root canal therapy for choosing the ideal rotary file. A number of nickel-titanium root canal shaping devices have been developed over the years. NiTi rotary systemsrsquo therapeutic efficacy is influenced by numerous factors and physical features. Clinical experience handling qualities safety and case results should ultimately determine the fate of an instruments design. This article outlines the distinct properties present applications and most recent advances in endodontic rotary files.
Recreation of Aesthetic Smile by Restoring Form, Function and Aesthetics: A Prosthodontic Approach: A Case Report
Authors: Khatuja Neha , Tarannum Fauzia , Katiyar Pratibha , Kumar Pandey Kaushik , Ali Mariyam
Published: January 2024

Smile designing primarily involves an enhancement towards appealing and elegant smile through appropriate dental restorations. Todayrsquos modern society gives a lot of precedence to a beautiful and healthy smile making it crucial for dental specialists to devise a comprehensive plan for fulfilling patientrsquos desires. Oral rehabilitation of patients in need of an appealing smile necessitates an integrative approach that involves a modification not only in the soft tissue architecture but also in the form and configuration of teeth. This clinical report describes a successful interdisciplinary approach for the treatment of an aesthetically and functionally compromised anterior dentition of a young female patient. Treatment plan included extraction of teeth with poor prognosis intentional root canal treatment and crown lengthening of maxillary and mandibular anterior teeth followed by conventional porcelain-fused-to metal fixed prosthesis. The final treatment outcome not only restored satisfactory function and aesthetics of the patient but also led to an improvement in the quality of life with a positive mind set towards her appearance.nbsp
Advances in Research trends
Authors: Suchetha A Dr.
Published: January 2024

None
Inter-Rater Agreement on the Scale Developed for Identification of Autism Spectrum Disorder in Early Childhood
Authors: H S Preethi , Murthy D Srinivasa , . Manjunath
Published: January 2024

Background Early identification and diagnosis of Autism spectrum disorder ASD is highly beneficial as it facilitates parents to access early intervention which leads to improved childrsquos quality of life. The newly developed scale for identifying ASD is comprised of 40 items which were extracted from 120 pooled items with each component extracted based on the sensitivity and specificity of the scale. The scale included items related to cognitive behaviour and communication components.Aim To estimate the inter-rater agreement on newly developed scale for identification of ASD.Methodology This prospective study was conducted in a tertiary care hospital setting involving children diagnosed with ASD. Two independent raters were involved in the study and the data collected was analysed to determine the inter-rater agreement.Results A total of 45 children were included in the study of which 32 were males and 13 were females and the mean age was recorded as 62.13plusmn1.6 months. The children were predominantly from urban domicile. Both the raters showed very good inter-rater agreement with K statistic varying between 0.683 to 1 and a P value of 0 was derived for each item of the scale mentioned.Conclusion Overall the study results demonstrated a very good inter-rater agreement on the scale among all the 40 items.
Relationship between Body Mass Index (BMI) and Foot Posture Index (FPI) Among Healthy Adults Aged 20-30 Years - An Observational Cross-Sectional Study
Authors: L K Shrihari , Kulkarni Sweta , Sabestin Dsouza Regina , Kour Harpreet
Published: January 2024

Background and Objective Obesity is the new epidemic globally. Obesity has also been linked to increased leg swing velocity higher metabolic expenditure and poorer postural stability all of which might affect foot function. Therefore this study was planned to determine the relationship between body mass index and foot posture index among healthy adults in the age group of 20-30 years studying at a medical university.Methods The study was conducted in the outpatient department of orthopaedics and physiotherapy SDM College of Medical Sciences and Hospital Dharwad India. This study was an observational cross-sectional study which included 50 healthy adult participants in the age group of 20-30 years based on the eligibility criteria. BMI was calculated using the Quelets index and foot posture scoring was done to determine the foot mass index. Descriptive analysis was done and presented as mean and standard deviation. Pearson correlation was done to determine the correlation between BMI and foot posture index. P less than 0.05 was considered significant.Results Increased body mass index was positively correlated with right and left foot posture indices. Conclusion Increased BMI leads to pronation of the feet. This can further cause the individual to walk slightly on the outside of the foot instead of the feet flat on the ground.
Spatiotemporal Gait Asymmetry Across the Lifespan: A Cross-Sectional Study in Adults
Authors: C Bhandarkar Aditi , Ravindra Savita , V Debur Ramesh
Published: January 2024

Background Human gait a complex motor activity essential for daily functioning is influenced by age health musculoskeletal and neurological factors. Appreciating the diverse features of gait with a specific focus on symmetry and asymmetry is essential for gaining insights into typical walking patterns. Moreover it plays a pivotal role in discerning potential irregularities associated with specific conditions underscoring the importance of recognizing asymmetry in the analysis of gait.Aim The current study aimed to determine the spatiotemporal asymmetry and assess the variations in these patterns throughout the lifespan.Methods A cross-sectional study was done using a convenience sample of seventy-two healthy adults between the ages 20 to 79 years. Subjects were divided into six groups according to the decade with 12 subjects included in each group. Gait analysis was done using a portable single layer pressure sensitive walkway measuring gait parameters Gait Rite. Subjects were asked to walk three times on the walkway at their preferred speed. The spatiotemporal parameters were measured.Results The results of the study indicated an increase in gait asymmetry across the age range. A total of nine spatiotemporal parameters were studied for evaluating asymmetry. Of these seven spatiotemporal parameters showed asymmetry across the age groups and an increase in asymmetry was observed across these parameters with advancing age.Conclusion The spatiotemporal gait asymmetry across the age groups in normal ambulatory individuals was established
Efektivitas Media Edukasi Leaflet tentang Infeksi Saluran Pernapasan Atas di Puskesmas Bandarharjo Kota Semarang
Authors: Martono Wahju Budi , Sari Astin Prima , Suryani Redi Eka , Balqis Indira Aura
Published: January 2024

Latar Belakang: Infeksi Saluran Pernapasan Atas (ISPA) merupakan penyakit menular yang memiliki risiko kematian tinggi di negara berkembang termasuk Indonesia. Insiden ISPA (per 1000 balita) di Indonesia tahun 2018 sebesar 20,06%. Pengabdian masyarakat dilakukan dengan memberi penyuluhan serta menilai efektivitas leaflet sebagai media edukasi terhadap pengetahuan masyarakat mengenai ISPA di Puskesmas Bandarharjo Semarang. Metode: Kegiatan pengabdian masyarakat ini berbasis penelitian intervensi yaitu quasi eksperimen dengan pre and post-test design untuk menilai efektivitas kegiatan. Pengabdian masyarakat dilakukan Desember 2022 di Puskesmas Bandarharjo. Responden adalah masyarakat umum yang datang ke penyuluhan di Puskesmas sejumlah 30 orang. Instrumen yang digunakan berupa kuesioner pengetahuan masyarakat tentang pentingnya pencegahan ISPA yang sudah dilakukan uji validitas dan uji reliabilitas. Pengambilan data menggunakan kuesioner yang dibagikan saat penyuluhan dengan dibantu oleh petugas Puskesmas Bandarharjo. Analisis univariat untuk melihat distribusi frekuensi dan dilakukan uji normalitas data menggunakan uji Shapiro wilk. Uji Wilcoxon dijalankan guna mengetahui efektivitas intervensi penyuluhan dengan leaflet tentang pentingnya pencegahan ISPA dengan membandingkan pre-test dan post-test. Hasil: Didapatkan hasil sebagian besar umur responden adalah usia lebih dari 35 tahun (73,68%), jenis kelamin perempuan (58%), tingkat pendidikan SMA (52%), bekerja (79%). Tingkat pengetahuan pada pretest sebagian besar baik (70%). Ada perbedaan signifikan skor pre-test dan post-test (p= 0,000). Peningkatan skor rata-rata sebesar 18,67. Kesimpulan: Sebagian besar responden memiliki pengetahuan pencegahan ISPA yang baik. Media edukasi leaflet efektif dalam meningkatkan pengetahuan masyarakat tentang ISPA.
Analisis Hubungan Antara Personal Hygiene Dan Penggunaan Alat Pelindung Diri Dengan Gejala Dermatitis Kontak Iritan Pada Pekerja Pabrik Tahu
Authors: Ropii Ahmad , Amalia Icca Stella
Published: January 2024

Latar Belakang : Dermatitis kontak iritan merupakan peradangan pada kulit yang disebabkan oleh kontak langsung dengan substansi yang menyebabkan reaksi inflamasi atau alergi, kemudian mengiritasi kulit, menjadikannya rusak dan merangsang reaksi peradangan. Data Dinas Kesehatan Kuningan Penyakit dermatitis merupakan 10 penyakit utama di Kabupaten Kuningan dengan jumlah 3.475 kasus. Tujuan penelitian ini adalah menganalisis hubungan antara personal hygiene dan penggunaan alat pelindung diri dengan gejala dermatitis kontak iritan pada pekerja pabrik tahu di Kabupaten Kuningan Tahun 2023. Metode : Jenis penelitian ini adalah analitik observasional dengan pendekatan cross sectional. Teknik pengambilan sampel menggunakan total sampling. Populasi dalam penelitian ini berjumlah 50 orang, besar sampel 50 responden. Instrumen yang digunakan adalah kuesioner dan pengambilan data dilakukan dengan wawancara. Analisis data menggunakan uji statistik Chi-Square dengan a = 0,05. Hasil : Distribusi frekuensi personal hygiene responden diketahui sebagian besar buruk yaitu sebesar 58%, penggunaan APD responden sebagian besar tidak lengkap yaitu sebesar 52% dan sebagian besar responden mengalami gejala dermatitis sebanyak 27 responden (54%). Hasil uji analisis chi-square menunjukan bahwa dalam penelitian ini didapatkan ada hubungan yang signifikan antara personal hygiene p=0,000 OR 2,177 (95%CI= 0,681-6,963) dan penggunaan APD p=0,001 OR 8,550 (95%CI= 2,354-31,060) dengan keluhan gejala dermatitis kontak iritan. Kesimpulan : Terdapat hubungan antara personal hygiene dan penggunaan APD dengan gejala dermatitis kontak iritan pada pekerja pabrik tahu di Kabupaten Kuningan Tahun 2023
Studi Kasus: Penerapan Intervensi ROM Untuk Meningkatkan Kekuatan Otot Ekstremitas Pasien Stroke Non Hemoragik
Authors: Fauziyah Naelly Nur , Sulistyanto Benny Arief , Wahyuningtyas Bekti
Published: January 2024

Pendahuluan: Stroke mengakibatkan kelemahan otot pada ekstremitas, sehingga diperlukan terapi pemulihan berupa latihan Range of Motion (ROM). Tujuan dari studi kasus ini adalah untuk mengidentifikasi keefektifan intervensi setelah dilakukan terapi ROM pada pasien stroke. Metode: Studi kasus ini mengaplikasikan tindakan keperawatan yang berbasis bukti (evidence-based practice) dengan mengobservasi satu pasien stroke yang mempunyai gangguan mobilitas fisik. Pasien diberikan terapi standar untuk terapi stroke dan ditambah dengan tindakan ROM selama tiga hari. Hasil: Setelah tiga hari dilakukan intervensi ROM, didapatkan peningkatan kekuatan otot dari skala satu pada hari pertama dilakukannya intervensi menjadi grade dua pada hari ketiga pasca intervensi. Tidak terdapat tanda-tanda komplikasi pasca tindakan. Kesimpulan: Terapi ROM aman diberikan pada pasien stroke dan tidak hanya dapat menurunkan kekakuan pada sendi tetapi juga dapat meningkatkan tonus/kekuatan otot pasien. Perawat disarankan untuk dapat memberikan terapi non farmakologi khususnya ROM sebagai terapi tambahan dalam pemberian asuhan keperawatan khususnya pada pasien stroke.
Senam Dalam Prespektif Islam: Studi Kasus Senam Aerobic Bagi Ibu-Ibu di Desa Wuled
Authors: Risdiani Risdiani , Setianto Gigih , Panggraita Gilang Nuari , Fatinabila Helmi
Published: January 2024

Latar belakang: Olahraga dalam Islam sangatlah dianjurkan. Salah satu jenis oleh raga yang dapat dilakukan adalah senam. Esensi senam adalah kreasi gerakan-gerakan tubuh yang teratur untuk mencapai tujuan tertentu diantaranya adalah kebugaran, kesehatan, dan penyembuhan atau bahan untuk mendapatkan bentuk tubuh yang indah. Akan tetapi Islam memberi batasan bagi umatnya dalam melaksanakan aktifitas termasuk senam. Metode: Penelitian ini menggunakan metode kualitatif diskriptif dengan pendekatan studi kasus senam Aerobic yang dilakukan oleh ibu-ibu di desa Wuled, Kecamatan Tirto, Kabuapaten Pekalongan. Hasil: Pelaksanaan senam Aerobic yang dilakukan oleh ibu-ibu di desa Wuled belum sepenuhnya sesuai dengan syariat Islam, dijumpainya pelaksanaan senam di tempat terbuka dan sebagian masih mengenakan busana yang ketat harus menjadi perhatian. Kesimpulan: Sebagai seorang muslimah harus benar-benar memahami tuntunan berolahraga menurut ajaran agama Islam sehingga aktivitas olahraga yang bertujuan untuk kebaikan, menjadi aktivitas yang tidak bertentangan dengan agama. Untuk itu disarankan dalam berolahraga mengenakan pakaian yang tidak memperlihatkan aurat dan lekuk tubuh, serta memilih tempat tertutup untuk menghindari diri dari fitnah.
Penerapan Relaksasi Otot Progresif Pada Pasien Post Operasi Laparatomi Benign Prostat Hyperplasia: Studi Kasus Di Rumah Sakit Umum Daerah Tugurejo Semarang
Authors: Nurkholila Mila , Sulistyanto Benny Arief
Published: January 2024

Latar belakang: Seorang pasien laki-laki usia 60 tahun menderita Benigna prostat hiperplasia (BPH). Pasien dilakukan tindakan pembedahan radical retropubic prostatectomy. Pengkajian pasien didapatkan keadaan umum baik, kesadaran composmentis, pasien juga mempunyai riwayat penyakit DM. Pasien mengeluh nyeri pada area operasi (dibawah pusar). Studi ini bertujuan untuk mengidentifikasi gambaran penerapan terapi relaksasi otot progresif pada nyeri akut terhadap pasien Benign Prostat Hyperplasia (BPH). Metode: Studi kasus ini mengaplikasikan tindakan keperawatan yang berbasis bukti (evidence based practice) dengan mengobservasi satu pasien post operasi laparotomi BPH. Pasien diberikan terapi standar dan ditambah dengan tindakan Relaksasi Otot Progresif (ROP) selama tiga hari masa perawatan post operasi. Pasien dievaluasi tiap hari yang meliputi skala nyeri, tanda-tanda vital, dan luka operasi. Hasil: Setelah tiga hari dilakukan intervensi ROP, pasien mengalami penurunan intensitas nyeri dari skala 4 pada hari pertama pasca operasi menjadi skala 1 pada hari ketiga. Pasien juga tidak terdapat tanda-tanda infeksi pada luka operasi. Namun demikian, keterbatasan kasus ini adalah penurunan skala nyeri sangat mungkin dikarenakan efek dari obat anestesi. Kesimpulan: Terapi relaksasi progresif terbukti aman diberikan pada pasien post operasi BPH dan juga dapat menurunkan intensitas nyeri pasien. Perawat disarankan untuk dapat memberikan ROP sebagai terapi tambahan dalam pemberian asuhan keperawatan khususnya pada pasien pasca operasi.
Aktivitas Larvasida N-Heksan Rimpang Kencur Terhadap Larva Aedes albopictus: Studi Pendahuluan
Authors: Mastura Nurul Izzah , Anwar Risyandi , Sayono
Published: January 2024

Latar belakang: Aedes albopictus merupakan vektor primer Chikungunya dan sekunder untuk Dengue dan Zika. Cara pengendalian spesies ini masih mengandalkan metode kimia seperti fogging dan larvasida. Kondisi ini telah berlangsung lama, sehingga muncul status resisten pada populasi Aedes dan menghambat upaya pengendalian penyakit-penyakit tersebut sehingga perlu dicari bahan aktif larvasida yang aman, mudah dan ramah lingkungan. Penelitian ini bertujuan untuk mengetahui aktivitas larvasida ekstrak n – heksan kencur terhadap larva Aedes albopictus. Metode: Penelitian eksperimen ini menerapkan Posttest Only Control Group Design dengan 5 konsentrasi ekstrak n-heksan kencur yaitu 10, 25, 50, 75, dan 100 ppm. Sebanyak 500 larva instar III Aedes albopictus instar menjadi subjek penelitian yang dibagi menjadi 5 kelompok perlakukan dan masing-masing direplikasi 5 kali sehingga setiap perlakuan berisi 20 larva. Analisis data menggunakan uji Kruskal-Wallis dan probit. Hasil: Kematian larva Ae. albopictus berkisar antara 3-100 % dengan konsentrasi efektif larvasida ekstrak n–heksan kencur (LC50 dan LC90) masing-masing 32,051 (29,741–34,419), dan 46,145 (42,395–51,531) ppm. Kesimpulan: Ekstrak n–heksan kencur dapat menjadi kandidat bahan aktif larvasida terhadap larva Aedes albopictus dengan tingkat efektivitas yang tinggi (LC50< 50 ppm).
Efektifitas Penggunaan Media Audio Visual Tentang Anemia Pada Ibu Hamil Di Kelurahan Gayamsari Dan Kelurahan Siwalan
Authors: Kamila Nurkholifah Natasya , Jusuf Jenny , Irsam M , Kukuh Nur
Published: January 2024

Latar belakang: Anemia masih menjadi salah satu faktor risiko kejadian morbiditas dan mortalitas maternal dan perinatal di Indonesia. Dalam upaya menurunkan risiko morbititas dan mortalitas maternal dan perinatal, puskesmas memiliki peran melalui pendampingan ibu hamil anemia. Pendampingan ibu hamil anemia tidak hanya didukung dari sistem manajemen puskesmas tetapi juga pada perilaku dan pengetahuan masyarakat di wilayah tersebut. Metode: Pengabdian ini menggunakan metode quasi eksperimen dengan pendekatan media edukasi audio visual. Edukasi berupa edukasi anemia pada ibu hamil diberikan kepada 40 responden. Pengabdian dilakukan pada bulan Maret 2023. Pengumpulan data menggunakan kuesioner pengetahuan dan sikap terhadap anemia dalam kehamilan serta pretest dan post-test. Hasil: Terdapat peningkatan nilai posttes dibandingkan pretes dengan peningkatan nilai sebesar 1,62 atau sebesar 20,5 persen. Kesimpulan: Intervensi berupa edukasi anemia pada ibu hamil dengan media audio visual  meningkatkan pengetahuan dan sikap responden terhadap anemia dalam kehamilan
Child Marriage Dan Upaya Pencegahannya Melalui Penerapan Model Public Health Literacy Pada Usia Remaja
Authors: Novita Medyati , Enos Karapa , Apriyana Irjayanti
Published: January 2024

Latar Belakang: Child marriage merupakan masalah kesehatan masyarakat yang berdampak pada kondisi fisik dan psikologi seorang remaja bahkan berisiko mengalami kematian. Proses perkembangan sosial dan seksual remaja menjadi hal yang penting untuk diperhatikan agar remaja dapat terhindar dari child marriage dan dampak yang ditimbulkannya, dengan cara memberikan dukungan edukasi dan pendampingan. Tujuan pengabdian ini adalah mengukur tingkat pengetahuan remaja tentang pencegahan pernikahan dini serta dampak yang ditimbulkannya serta mengupayakan remaja agar dapat memiliki proteksi diri terhadap berbagai faktor yang dapat memicu terjadinya pernikahan diusia remaja. Metode: Pengabdian masyarakat ini menggunakan model public health literacy yaitu pendekatan dengan metode edukasi dan pendampingan terhadap kelompok remaja gereja sebanyak 40 remaja. Adapun tahapan kegiatan diawali dengan pemberian pre-test untuk mengukur tingkat pengetahuan remaja tentang pengertian child marriage serta dampaknya terhadap perkembangan fisik, psikis serta kehidupan sosial remaja.tahapan kegiatan berikutnya dengan pemberian edukasi serta pendampingan Selanjutnya, pemberian post-test sebagai tahapan akhir kegiatan untuk mengetahui perbedaan tingkat pengetahuan sebelum dan sesudah diberikan edukasi dan pendampingan, dengan analisis data menggunakan Wilcoxon Signed Ranks Test. Hasil : Terdapat perbedaan yang signifikan pada tingkat pengetahuan remaja sebelum dan sesudah melalui penerapan public health literacy dengan nilai (p= 0,000) Kesimpulan : Pemberian edukasi disertai pendampingan sebagai sebuah pendekatan yang digunakan dalam model public health literacy telah memberikan sumbangsih yang signifikan terhadap peningkatan pengetahuan remaja terhadap child marriage dan dampaknya.
Olahraga Sebagai Kegiatan Positif Pada Siswa SMP Muhammadiyah 2 Kebumen
Authors: Muhibbi Muhammad , Yogaswara Andre , Dhuha Ahad Agafian , Abubakar Sayid Fariz Bin Seh
Published: January 2024

Latar belakang: Kualitas hidup yang baik akan tercipta salah satunya melalui kegiatan yang positif. Banyak kegiatan positif yang dapat dilakukan anak remaja salah satunya dengan berolahraga. Ditinjau dari pengertian, tujuan dan manfaat olahraga, olahraga merupakan kegiatan yang positif jika dilakukan dengan benar dan baik. Dalam olahraga terdapat nilai-nilai yang positif diantaranya; kejujuran, fair play, sportif, empati, simpati, sikap mental yang baik, tanggung jawab, menghormati orang lain, disiplin, motivasi, dan kerjasama. Metode:  Kegiatan pengabdian ini berbentuk Community-Based Participatory Research (CBPR). Desain dalam penelitian pengabdian ini menggunakan pre-test post-test group design. Teknik pengambilan data dalam penelitian pengabdian ini menggunakan teknik observasi, kuesioner (angket), wawancara, dan dokumentasi. Instrumen yang digunakan terkait teknik pengambilan data yaitu; panduan observasi, penyebaran angket, panduan wawancara, dan kamera/analisis dokumen-dokumen sebelumnya. Dalam penelitian pengabdian ini menjelaskan pentingnya berolahraga dengan hasil penelitian terdapat peningkatan dari tiga indikator (pemahaman, motivasi, dan ketertarikan) sebanyak 22,71%. Kesimpulan: Pentingnya kegiatan positif terhadap siswa SMP dengan tujuan untuk menghindari hal-hal yang tidak diinginkan oleh orang tua maupun guru di sekolah, dan terciptanya siswa yang berkarakter baik. Salah satu kegiatan positif tersebut yaitu melakukan olahraga di waktu luang. Alangkah lebih baiknya kalau setiap sekolahan memberikan dukungan penuh terhadap siswa untuk melakukan kegiatan olahraga dengan menyediakan sarana prasarana seperti ekstrakurikuler.
KEMAMPUAN KONEKSI MATEMATIS SISWA MELALU MODEL MEANINGFUL INSTRUCTIONAL DESIGN (MID) PADA MATERI SISTEM PERSAMAAN LINEAR DUA VARIABEL (SPLDV)
Authors: Sapurata Juang , Prihatingtyas Nindy Citroresmi , Nurhayati Nurhayati
Published: January 2024

Penelitian ini bertujuan untuk mengetahui kemampuan koneksi matematis siswa melalui model meaningful instructional design (MID) terhadap kemampuan koneksi matematis siswa, dan motivasi belajar siswa saat pembelajaran dengan model MID pada materi SPLDV dikelas VIII SMP Negeri 11 Singkawang. Jenis yang digunakan dalam penelitian ini adalah Quasi Experimental Design dengan desain penelitian The Nonequivalent Posttest Only Control Group Design. Instrumen  yang digunakan dalam penelitian ini adalah tes kemampuan koneksi matematis siswa, angket motivasi belajar siswa, dan lembar keterlaksanaan model MID. Berdasarkan hasil analisis disimpulkan bahwa; 1) Terdapat perbedaan kemampuan koneksi matematis siswa antara kelas yang menggunakan model pembelajaran MID dengan kelas yang menggunakan model pembelajaran langsung. 2) Pengaruh model pembelajaran MID terhadap kemampuan koneksi matematis siswa tergolong besar. 3) Motivasi belajar siswa yang diajarkan dengan model pembelajaran MID tergolong tinggi. 4) Keterlaksanaan model pembelajaran MID telah terlaksana dengan sangat baik. 
PENERAPAN MODEL PEMBELAJARAN SOMATIS, AUDITORI, VISUAL, INTELKTUAL (SAVI) UNTUK MENINGKATKAN KEMAMPUAN KOMUNIKASI MATEMATIS SISWA PADA MATERI FUNGSI LINEAR
Authors: Putra Issu , P Nindy Citroresmi , Nurhayati Nurhayati
Published: January 2024

Tujuan Penelitian ini adalah untuk mendeskripsikan penerapan model pembelajaran SAVI untuk meningkatkan kemampuan komunikasi matematis siswa, ketuntasan, dan aktivitas belajar siswa saat pembelajaran dengan model SAVI pada materi fungsi linear kelas X SMA Negeri 2 Singkawang. Penelitian ini menggunakan desain Quasi Eksperimental dengan rancangan Nonequivalent Control Grup Design. Populasi dalam penelitian ini adalah semua kelas X SMA Negeri 2 Singkawang yang terdiri dari 6 kelas yang berjumlah 184 siswa. Sampel diambil dengan teknik purposive sampling. Adapun sampel yang dipilih terdiri dari dua kelas yaitu kelas X. IIS-4 sebagai kelas eksperimen dan kelas X. IIS-3 sebagai kelas control. Hasil analisis menunjukkan: 1) terdapat peningkatan kemampuan komunikasi matematis siswa setelah diterapkan model pembelajaran SAVI; 2) terdapat perbedaan secara signifikan antara peningkatan kemampuan komunikasi siswa pada materi fungsi linear antara siswa yang mendapat pembelajaran menggunakan model pembelajaran SAVI dan siswa yang mendapat pembelajaran menggunakan model pembelajaran langsung; 3) hasil belajar siswa tercapai (mencapai KKM 70) baik secara individual maupun klasikal dengan diterapkan model pembelajaran SAVI; 4) aktivitas belajar siswa menjadi tergolong aktif setelah diterapkan model pembelajaran SAVI.
PENINGKATAN KEBERANIAN DENGAN STRATEGI TEAM ASSISTED INDIVIDUALIZATION
Authors: Fitriyani Marlinda
Published: January 2024

Keberanian belajar matematika terdapat beberapa indikator. Indikator-indikator tersebut antara lain : a) mau mencoba hal-hal yang baru, b) mau mengemukakan pendapat, c) mampu mengendalikan rasa takut, d) mau menghadapi tantangan. Keberanian merupakan kemampuan mengendalikan situasi untuk bertanya dan menjawab, sehingga meraih hasil belajar yang maksimal. Tujuan penelitian untuk mengkaji peningkatan keberanian matematika bagi siswa SMP Negeri 3 Colomadu kelas IX F semester ganjil tahun ajaran 2013/2014 melalui strategi pembelajaran Team Assisted Individualization. Metode yang digunakan dalam penelitian ini adalah metode penelitian tindakan kelas yang terdiri dua siklus. Data yang diperoleh berupa nilai tes pada akhir siklus I dan pada akhir siklus II. Analisis data dilakukan dengan analisa deskriptif komparatif yaitu membandingkan nilai tes pada kondisi awal, siklus I dan pada siklus II. Hasil penelitian menunjukkan peningkatan keberanian siswa yang dapat dilihat dari meningkatnya indikator-indikatornya meliputi: 1) siswa mampu mencoba hal-hal baru sebelum tindakan 16,21%, siklus I 45,16%, dan siklus II 67,74%, 2) siswa mampu mengemukakan pendapat sebelum tindakan 22,58%, siklus I 51,61%, dan siklus II 77,41%, 3) siswa mampu mengendalikan rasa takut sebelum tindakan 19,35%, siklus I 58,06%, dan siklus II 74,19% 4) siswa mampu menghadapi tantangan dengan menjawab soal sebelum tindakan 22,58%, siklus I 54,83%, dan siklus II 80,64% dan siswa yang nilainya tuntas KKM sebelum tindakan 19,35%, siklus I 61,29%, dan siklus II 83,87%. Berdasarkan uraian diatas disimpulkan bahwa penerapan strategi pembelajaran Team Assisted Individualization dalam pembelajaran matematika dapat meningkatkan keberanian siswa dalam pembelajaran matematika
ANALISIS KESADARAN MASYARAKAT PULAU LINGAYAN TERHADAP PENDIDIKAN
Authors: Utomo Jepri
Published: January 2024

ABSTRAK

 

Penelitian ini bertujuan untuk menganalisis faktor-faktor yang melatarbelakangi rendahnya kesadaran masyarakat Pulau Lingayan terhadap pendidikan. Metode penelitian ini adalah kualitatif deskriptif berbentuk survei dengan  teknik pengumpul data observasi langsung, komunikasi langsung, dan studi dokumenter (bibiliografis). Adapun alat pengumpul data yang digunakan berupa observasi, wawancara (interview), dan panduan dokumentasi. Penelitian ini menggunakan teknik analisis data model interaktif Miles dan Huberman yang dilakukan melalui 4 tahapan, yaitu: pengumpulan data, reduksi data, display data, dan kesimpulan/verivikasi. Hasil penelitian menunjukkan bahwa rendahnya kesadaran masyarakat Pulau Lingayan terhadap pendidikan disebabkan oleh faktor: 1) Mindset masyarakat setempat/orang tua peserta didik yang menganggap pendidikan bukan prioritas utama untuk masa depan anak-anaknya. 2) Satu diantara ukuran masyarakat/orang tua dalam menilai anaknya berbakti adalah anak menuruti/bersedia membantu orang tuanya bekerja, meskipun pada saat jam belajar di sekolah sedang berlangsung. 3) Mindset masyarakat/orang tua menganggap bepergian ke pasar adalah hal yang tidak kalah pentingnya dengan kegiatan bekerja. 4) Mayoritas masyarakat yang mendiami Pulau Lingayan berlatarbelakang ekonomi kelas bawah. Mata pencahariaan yang dijalani hanya mencukupi kebutuhan dasar sehari-hari. Mereka cenderung berpola pikir “sudah sangat bersyukur jika bisa makan sehari-hari dan anak-anak bisa calistung (baca, tulis, hitung)”. Sehingga pendidikan tidak menjadi prioritas penting.