bluuebunny/crossref_metadata_2025 huggingface dataset:
The Therapeutic Potential of Targeting the Angiotensin Pathway as a Novel Therapeutic Approach to Ameliorating Post-surgical Adhesions
Authors: Khalili-Tanha Ghazaleh , Khalili-Tanha Nima , Nazari Seyedeh Elnaz , Chaeichi-Tehrani Negin , Khazaei Majid , Aliakbarian Mohsen , Hassanian Seyed Mahdi , Ghayour-Mobarhan Majid , Ferns Gordon A. , Avan Amir
Published: June 2021

Background:

Post-surgical adhesion is a common complication after abdominal or pelvic surgeries.
Despite improvements in surgical techniques or the application of physical barriers, few improvements have
been achieved. It causes bowel obstruction, pelvic pain, and infertility in women and has an adverse effect on
the quality of life. Renin-Angiotensin System (RAS) is traditionally considered a blood pressure regulator.
However, recent studies have indicated that the RAS plays a vital role in other processes, including oxidative
stress, fibrosis, proliferation, inflammation, and wound healing. Angiotensin II (Ang II) is the main upstream effector
of the RAS that can bind to the AT1 receptor (ATIR). A growing body of evidence has revealed that targeting
Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II type 1 Receptor Blockers (ARBs),
and Direct Renin Inhibitors (DRIs) can prevent post-surgical adhesions. Here we provide an overview of the
therapeutic effect of RAS antagonists for adhesion.

Methods:

PubMed, EMBASE, and the Cochrane library were reviewed to identify potential agents targeting
the RAS system as a potential approach for post-surgical adhesion.

Results:

Available evidence suggests the involvement of the RAS signaling pathway in inflammation, proliferation,
and fibrosis pathways as well as in post-surgical adhesions. Several FDA-approved drugs are used for targeting
the RAS system, and some of them are being tested in different models to reduce fibrosis and improve
adhesion after surgery, including telmisartan, valsartan, and enalapril.

Conclusion:

Identification of the pathological causes of post-surgical adhesion and the potential role of targeting
the Renin-Angiotensin System may help to prevent this problem. Based on the pathological function of
RAS signaling after surgeries, the administration of ARBs may be considered a novel and efficient approach to
prevent postsurgical adhesions. Pre-clinical and clinical studies should be carried out to have better information
on the clinical significance of this therapy against post-surgical adhesion formation.
miRNA and Nanoparticle Conjugate as a Future Therapeutic Approach
Authors: Acharya Rituparna
Published: June 2021

Micro RNAs are naturally occurring RNA molecules that help in the
degradation of mRNA molecules sequence specifically. They degrade the mRNA
molecules and thus inhibit the formation of protein after translation. miRNA expression
varies from tissue to tissue and from one disease condition to other. Thus this molecule
becomes a target of therapy in various types of disease conditions. But, the use of bare
miRNAs has several drawbacks as they may degrade in the body fluid due to their
fragile nature. So, in this regard nanoparticles have a very vital role to overcome these
disadvantages. In this study, we intended to discuss the various forms of miRNA
therapeutic approaches, along with various types of nanoparticles that may carry the
miRNA and its antagomirs to the target site.
De invloed van ouderlijke echtscheiding op schoolloopbanen
Authors: Havermans Nele , Vanassche Sofie , Matthijs Koen
Published: June 2021

In dit onderzoek wordt de invloed van een echtscheiding op drie scharniermomenten in de schoolloopbaan van kinderen onderzocht aan de hand van data van het onderzoeksproject Scheiding in Vlaanderen. De resultaten tonen aan dat kinderen van gescheiden ouders significant minder kans hebben om een ASO‐richting te volgen in het secundair onderwijs en om een diploma hoger onderwijs te behalen. De effecten van een echtscheiding op de onderwijsuitkomsten van kinderen verschillen naargelang het opleidingsniveau van ouders: kinderen van laagopgeleide ouders ondervinden een sterker negatief effect van een echtscheiding op hun schoolloopbaan dan kinderen van hoogopgeleide ouders. Leerlingen die reeds een moeilijkere positie hebben in het onderwijs, lopen hierdoor het risico nog verder achterop te geraken. De resultaten benadrukken de nood aan meer aandacht voor de thuissituatie van kinderen in het Vlaams onderwijsbeleid.
Abstract :
The influence of divorce on three key moments in children’s educational careers is investigated in this article. Data of the research project Divorce in Flanders are used to investigate this relationship.  The results demonstrate that children of divorced parents have a lower probability of following a general track in secondary school and attaining a degree of higher education. Further, the results show that the effects of divorce on the educational outcomes of children differ according to parents’ educational level. Children of lower educated parents are more negatively affected by a parental divorce than children of high educated parents. So, to put it differently, children who already struggle more in school on average, risk even more difficulties when parents divorce. The results stress the need for more policy attention for children’s family life.
Het professioneel zorg‐ en psychofarmacagebruik van gescheiden vrouwen en mannen : wat is de rol van informele steun ?
Authors: Buffel Veerle , Colman Elien , Bracke Piet
Published: June 2021

Deze studie vergelijkt het zorg‐ en psychofarmacagebruik omwille van psychische klachten van gescheiden personen (met een nieuwe partner of alleenstaand) met gehuwden. Binnen het theoretisch kader van de crowding‐in/out hypothesen, stellen wij ons de vraag of de beschikbaarheid van informele steun professioneel zorggebruik aanmoedigt of substitueert. Logistische regressieanalyses werden uitgevoerd afzonderlijk voor mannen (N=3020) en vrouwen (N=3450) met het contacteren van een huisarts, psychiater, psycholoog en psychofarmacagebruik als afhankelijke variabelen. Gescheiden alleenstaanden rapporteren het hoogste zorg‐ en psychofarmacagebruik.  Gescheiden vrouwen (en vooral alleenstaande) contacteren vaker een huisarts, psychiater en psycholoog, ongeacht hun mentale gezondheid, informele steun en sociaaleconomische achtergrond. Vrouwen die kunnen rekenen op emotionele steun van familie en niet‐familieleden zijn meer geneigd om een huisarts te contacteren. Bij mannen beïnvloedt de aanwezigheid van emotionele steun van leden buiten de familie het contacteren van elk type van zorgverlener. Deze bevindingen zijn in lijn van de crowding‐in hypothese.
Abstract :
This study compares mental health care and psychotropic drug use of the divorced (re‐partnered or single) to the married. Within the theoretical framework of crowding in/out thesis, we question whether the availability of informal support, facilitates or substitutes formal care seeking. Logistic regression analyses were performed for women (N=3450) and men (N=3020) to determine the correlates of contacting a GP, a psychiatrist, a psychologist and taking psychotropic drugs. Divorced singles report the highest mental health care and psychotropic drug use. Divorced women (especially singles) contact more often each type of health care provider, regardless of their mental health, informal support and socio‐economic background. Women who can rely on the support of family and non‐family members are more inclined to contact a GP. With regard to men, informal support of non‐family members positively influences each type of care seeking. These findings are in line with the crowding‐in thesis.
Frequenter contact met ouders bij volwassen mannen en vrouwen na echtscheiding
Authors: Van Rossem Tina , Jappens Maaike , Theunis Lindsay , Van Bavel Jan
Published: June 2021

Aan de hand van data van de survey 'Scheiding in Vlaanderen' onderzoeken we in dit artikel het verband tussen een echtscheiding van volwassen kinderen en de frequentie van ontmoetingen met hun ouders. Daarbij houden we zowel rekening met door de volwassen kinderen als door de ouders gerapporteerde contactfrequenties. De resultaten tonen aan dat gescheiden personen meer contact hebben met beide ouders dan gehuwden. Meer specifiek geldt dat de frequentie van ontmoetingen het hoogst is wanneer men na de echtscheiding niet samenwoont met een nieuwe partner. De verschillen naargelang de huwelijks‐ en partnerstatus zijn beduidend groter voor zoons dan voor dochters.
Abstract :
Using data from the survey ‘Divorce in Flanders’, we study the relationship between the divorce of adult children and the frequency of face‐to‐face contacts with their parents. Doing so, we take into account contact frequencies reported by the adult children as well as frequencies reported by their parents. The results indicate that, when compared to married persons, divorced people have more face‐to‐face contact with both of their parents. More specifically, the frequency of encounters is the highest when one is not living with a new partner after the divorce. The differences according to the marital and partner status are significantly larger for sons than for daughters.
Voor eeuwig en altijd ? : Houdingen omtrent huwen en scheiden bij Vlaamse jongeren met gehuwde en gescheiden ouders
Authors: Theunis Lindsay , Jappens Maaike , Vandenbroeck Bente , Van Bavel Jan
Published: June 2021

Op basis van antwoorden van 874 jongeren (14‐ t.e.m. 25‐jaar) in de survey ‘Scheiding in Vlaanderen’ (N = 874) onderzochten we verschillen in de houdingen ten aanzien van huwen en scheiden tussen jongeren met gehuwde en jongeren met gescheiden ouders. Daarnaast gingen we ook na of de mate van ouderlijk conflict en de kwaliteit van de ouder‐kindrelaties een rol spelen en zoomden we dieper in op verschillen in houdingen binnen de groep echtscheidingsjongeren. Vooral de echtscheiding op zich blijkt van belang te zijn: jongeren met gescheiden ouders willen vaker niet trouwen, schatten hun eigen echtscheidingskans hoger in en nemen liberalere houdingen aan ten opzichte van het huwelijk dan jongeren waarvan de ouders nog steeds gehuwd zijn. Verschillen tussen echtscheidingsjongeren onderling worden voornamelijk verklaard door de verblijfsregeling en de mate waarin de jongere nog steeds geraakt wordt door de echtscheiding.
Abstract :
Based on data obtained from 14 to 25 year olds in the survey ‘Divorce in Flanders’ (N = 874), we investigated the relationship between adolescents’ attitudes towards marriage and divorce and the marital status of their parents. We also examined whether parental conflict and parent‐child relationships play a role and we took a closer look at differences within the group of adolescents with divorced parents. Parental divorce as such appeared to be a major factor: adolescents from dissolved families are less willing to marry, perceive their chance of ever getting divorced as higher and have more liberal attitudes towards marriage than adolescents from intact families. Differences among children of divorce are related to the residence arrangement and to the way they are coping with the divorce.
(Groot)ouders over de echtscheiding van hun zoon of dochter
Authors: Jappens Maaike , Van Bavel Jan
Published: June 2021

Op basis van de antwoorden van meer dan 1300 respondenten die deelnamen in de studie ‘Scheiding in Vlaanderen’, onderzoeken we hoe ouders ermee omgaan als hun zoon of dochter een echtscheiding doormaakt. De resultaten maken duidelijk dat de impact van een echtscheiding verder reikt dan ex‐partners en hun kinderen. De meeste ouders verleenden hun zoon of dochter steun tijdens de echtscheiding, zowel emotioneel, praktisch als financieel. Een meerderheid van de ouders vond een echtscheiding in de gegeven omstandigheden het beste voor zoon of dochter, maar sommigen keurden de echtscheiding af of deden pogingen tot verzoening. Indien er kleinkinderen aanwezig waren, maakten vooral grootouders van vaderskant zich zorgen over de nadelen voor hen. De echtscheiding viel behoorlijk wat ouders zwaar. Dit beterde na verloop van tijd, maar sommigen hadden het ook vele jaren na de echtscheiding nog moeilijk, vooral als het om een gescheiden zoon ging en als er kleinkinderen bij betrokken waren.
Abstract :
Based on the answers of more than 1300 respondents in the study ‘Divorce in Flanders’, we investigate how parents cope with the divorce of their son or daughter. Results clearly imply that the impact of a divorce reaches beyond divorcing ex‐partners and their children. Most parents provided their son or daughter with emotional, practical as well as financial support during the divorce. A majority of parents agreed that the divorce was the best solution in the given circumstances, but some totally disapproved of the divorce or tried to reconcile. If there were grandchildren involved, especially paternal grandparents considered divorce was detrimental for them. A lot of parents struggled with their child’s divorce. This got better with time, but for some parents it was still difficult many years later, especially if it concerned the divorce of a son and if there were grandchildren in the dissolved marriage.
De Onzichtbare Scheidingsgolf : Een analyse van relatieontbinding van samenwonenden en gehuwden in België
Authors: Van den Berg Layla , Mortelmans Dimitri
Published: June 2021

 
Abstract : 
This article studies relationship break‐up among married and cohabiting couples, based on the Belgian data ofthe Crossroads Bank of Social Security. The results are based on a sample of couples marrying for the first timeor starting to cohabit for the first time between 1999 and 2001. The sample is followed over time until 2013. Thepurpose of this study is to gain insight in relationship break‐up of married and cohabiting couples using registerdata. Given the fact that cohabiting couples are underestimated in official statistics because these only use offi‐cially registered partnerships (e.g. legal cohabitation), cohabiting couples are identified in this article on the basisof their LIPRO typology giving a more correct insight in relationship dynamics of cohabiting couples.The article looks at patterns of relationship dissolution with the aid of survival analysis and a discrete time eventhistory analysis for three relationship trajectories: marriages formed without premarital cohabitation, marriagesformed after a period of premarital cohabitation and cohabitations not (yet) converted into a marriage duringthe observation period. The results show that cohabiting couples not marrying during the observation period,have a much lower chance to be together after 14 years compared to the married couples. The differences be‐tween married couples with and without a period of unmarried cohabitation are more limited. Further, we findthat a break‐ups are more common among couples who start living together at an early age, start from a weakereconomic background or those that do not have children during the first four years. The association betweenrelationship break‐up and these background characteristics is similar among all three relationship trajectoriesstudied.
CuBr-усилитель яркости с частотой следования импульсов сверхизлучения/усиления до 200 kHz
Authors: Мусоров И.С. , Торгаев С.Н. , Евтушенко Г.С.
Published: June 2021

The paper presents the results of research and development of a high-speed brightness amplifier based on copper bromide vapor active medium, with a pulse repetition frequency of up to 200 kHz. This became possible due to the use of the reduced input energy into the discharge mode (less than 60 µJ / cm3 per pulse), by shortening the leading edge of the high-voltage pump pulse to 20 ns and the duration (at half-height) to 30 ns.
Моделирование влияния агломерации графена на механические свойства керамических композитов с графеном
Authors: Шейнерман А.Г. , Красницкий С.А.
Published: June 2021

A model is proposed that describes the porosity, hardness, and fracture toughness of ceramic composites with agglomerates of graphene platelets. The model assumes that the agglomeration of graphene platelets occurs during the hot pressing of such composites, and pores are formed around the agglomerates. Within the model, the dependences of porosity, hardness, and fracture toughness of ceramic/graphene composites on the volume fraction of graphene are calculated. It is shown that the formation of pores explains the experimentally observed drop in the hardness and fracture toughness of composites for the volume fraction of graphene exceeding a critical value. The results of the model agree with the experimental data for the composites Al2O3-WC-TiC-Gr.
Регистрация однофотонного сигнала от низколетящих спутников для целей спутникового квантового распределения ключей
Authors: Хмелев А.В. , Дуплинский А.В. , Майборода В.Ф. , Бахшалиев Р.М. , Баланов М.Ю. , Курочкин В.Л. , Курочкин Ю.В.
Published: June 2021

A ground-based receiving station for quantum key distribution with a satellite, capable of analyzing the quantum polarization states of photons, is demonstrated. In the experiment on tracking a low-Earth orbit satellite, the residual tracking error by the ground station does not exceed 10 μrad, which ensures stable reception of the optical signal in four channels of the polarization state decoder. An estimation of the efficiency of registration of an optical signal in the mode of tracking satellites is carried out.
Power representation in the leadership of academic libraries in Indonesia
Authors: Laugu Nurdin
Published: June 2021

Introduction. Libraries as a  dynamic environment have supported  dynamic interactions in various aspects of life. These interactions occur in several  frames such as  culture, social, and ideology that pose power in library leadership at universities.

Data Collection Method. In-depth interviews with nine informants, consisting of heads, librarians, and library staff in three libraries, conducted unstructurally between 2018 and 2020. Interview data was used as the main data collection  technique,  supported by observations and documentation.

Data Analysis. Miles and Huberman's model with three stages, i.e. data reduction, data presentation, and conclusion or verification, was employed to interpret findings.

Results and Discussion. The results showed  five main issues, which are directly related to power representation in libraries. These issues include religious understanding, institutional vision, temporary power, seniority of library personnels, and the influence of the library collection development.

Conclusion. The representation of power in library leadership practices has emerged in the frames of religiosity, organizational ideology, seniority, power, and impact of library  collection. Therefore, this research contributes to library science theorists and practitioners concerning the awareness of the power representation issues.
Persepsi pemustaka terhadap layanan perpustakaan “Rumah Ilmu” Universitas Negeri Semarang
Authors: Handoyo Mokhamad Zakaria Eko , Burhanudin Muhamad , Rahmadhani Amalia
Published: June 2021

Introduction. Universitas Negeri Semarang (UNNES) Main Library is committed to providing excellent services. One of the activities is to understand the users’ needs. This paper investigates the users’ perceptions of UNNES Main Library services. The objectives of the study include; (1) determining users’ perception on library services quality, (2) Examining satisfaction level of library services, (3) Measuring users’satisfaction level based on Service Satisfaction Index.

Data Collection Methods. The paper used a quantitative methods approach with questionnaires, involving 203 library users, selected randomly.

Data Analysis. The data were descriptively analysed by using an online survey tool (SurveyGizmo.com).

Results and Discussion. The results report; (1) Users were satisfied with library services quality, but less satisfied with book collections; (2) Satisfaction level of library services was satisfactory; (3) Average score of customer satisfaction was 2.89, within the interval scale of 2.52 to 3.27.

Conclusions. Based on the findings concluded that user’s perceptions of UNNES library services were satisfied and furthermore, the UNNES library will continue to improve the quality of services until it achieves very satisfying results.
A COST VARIATION ANALYSIS STUDY OF DRUGS USED IN THE MANAGEMENT OF BENIGN PROSTATIC HYPERPLASIA AVAILABLE IN THE INDIAN MARKET
Authors: RANI VIBHA , VENEPALLY SAILAXMI
Published: June 2021

Objectives: The objectives of the study are to evaluate the cost variation and cost ratio of different brands of the drugs used in the treatment of benign prostatic hyperplasia (BPH).

Methods: The cost of alpha-blockers and 5 alpha-reductase inhibitors used in the treatment of BPH was noted from CIMS (Oct 2019–Jan 2020), Drugs Update, and Medline. The differences between the maximum and minimum cost of various brands of the same drug were analyzed and percentage variation in the cost was calculated. The results of the study were expressed in absolute numbers and percentages.

Results: All the drugs used in the treatment of BPH are only available in tablet and capsule forms, in 10 different dosages and in 242 different brand names, of which 10 mg alfuzosin and 2.5 mg finasteride have the highest (518) and lowest (14) percentage of cost variation, while 0.4 mg tablet form of tamsulosin is available in the maximum number of brands-41.

Conclusion: This pharmacoeconomic study reveals that there is wide variation in the cost of most of the drugs used in the treatment of BPH. Therefore, it is very much essential for both government and pharmaceutical companies to make combined efforts to reduce the cost of these drugs, which will reduce the economic burden on the patients and also reduce the overall health care costs.
“SLURRED SPEECH AND TREMORS RESULTING FROM ANTIPSYCHOTIC THERAPY IN A PATIENT WITH BIPOLAR DISORDER: A CASE REPORT”
Authors: PADMAKAR SOMANABOINA
Published: June 2021

Bipolar disorder (BD) is a mood disorder where moods can fluctuate from depression to elevated moods referred to as mania. BD is currently divided into three types. All three types involve clear changes in mood, energy, and activity levels. BD-I is the most severe disorder and symptoms of mania can be so severe that they can require psychiatric hospitalization. BD-II has the same symptoms as BD-I; however, it was described as hypomania because they are less severe than in pure mania. Cyclothymia, also known as a cyclothymic disorder, is a minor mood disorder characterized by fluctuating low-level depressive symptoms and periods of mild mania, similar to BD-II. Mood stabilizers and second-generation antipsychotics are first-line for treating and maintaining a stable mood. This study related to a case report on slurred speech and tremors induced by antipsychotics in a patient suffering from BD.
GOKHRU (TRIBULUS TERRESTRIS AND PEDALIUM MUREX): MEDICINAL IMPORTANCE OF CHOTA GOKHRU AND BADA GOKHRU IN AYURVEDA AND MODERN SCIENCE
Authors: CHOUDHARY SHAILJA , KAURAV HEMLATA , CHAUDHARY GITIKA
Published: June 2021

Tribulus terrestris and Pedalium murex are the two popular herbal plants originated from a very famous Ayurvedic plant named Gokshuru. These plants are well known for their medicinal importance. In Ayurveda, T. terrestris is known as laghu gokhshuru and P. murex is known as brihat gokshuru. The fruits of T. terrestris plant are slightly astringent in taste while the fruits of P. murex are somewhat sweeter in taste. The fruits are used to treat various diseases such as urinary disorder adrenal stone. In this current paper, we have discussed the pharmacological, Ayurvedic and folk uses of these plants in every region of the world. From various reported studies, it was found that the T. terrestris plant carries much medicinal importance while the P. murex fruits is only used as a substitute or as an adulterant of the T. terrestris plant. It was found that the T. terrestris plant is mainly used to cure urinogenital disorders and kidney disorders such as renal and gall bladder stone. On the other hand, the P. murex plant carries aphrodisiac property and mainly used to cure sexual disorders like infertility, erectile dysfunctioning in both male and females. It was also found that these plants have some similar phytochemical constituents which possess aphrodisiac, anti-inflammatory, demulcent, diuretic properties, and also used to cure other diseases such as cough, asthma, cardiac disease, vesical calculi, and gall bladder stone. These plants are known for major therapeutic properties such as anti-ulcerative, antiurolithic, anticancer, aphrodisiac, analgesic, stomachic, anti-hypertensive, diuretic, urinary anti-infective, cardio tonic, antibacterial, anti-inflammatory, nephroprotective, antispasmodic, anthelmintic, and anti-carcinogenic.
A COMPARATIVE STUDY OF CAUDAL BLOCK AND ULTRASOUND-GUIDED TRANSVERSUS ABDOMINIS PLANE BLOCK WITH LEVOBUPIVACAINE AND DEXAMETHASONE AS ADDITIVE IN EXTRAPERITONEAL LOWER ABDOMINAL SURGERIES IN PEDIATRICS
Authors: GHODKE SANDHYA , N MADHAVI , RN HIREMATH
Published: June 2021

Objective: The objective of the study was to evaluate the efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus caudal block for post-operative analgesia with levobupivacaine and dexamethasone as additive in extraperitoneal lower abdominal surgeries in pediatrics as there is no available literature showing the same.

Methods: This is a randomized control study carried out between two groups among 50 children (1–8 years of age), both sexes, posted for elective extraperitoneal lower abdominal surgeries after taking informed consent from parents. Fifty children were randomly allocated into two groups, 25 in each group. Caudal epidural (CE) group received general anesthesia and caudal block with 1 ml/kg of 0.2% levobupivacaine and 0.1 mg/kg dexamethasone. TAP group received general anesthesia and ultrasound-guided TAP block with 0.5 ml/kg of 0.2% levobupivacaine and 0.1 mg/kg dexamethasone. Data were collected by means of pre-designed format with pre-/post-operative assessment with standardized scores.

Results: The mean age of the patients was 4.84 (SD=2.29). Mean face, legs, activity, cry, and consolability score was low and non-significant before shifting the patient (<2 h post-operative [post-op]) in both the groups. Thereafter from 2 to 12 h, the mean score increased to 4.92 (SD=2.72) in the CE group and 2.92 (SD=2.17) in the TAP group and the difference was statistically significant at 2 h, 4 h, 6 h, and 12 h postoperatively. Mean time to rescue analgesia in the CE group was 4.96 h (SD=4.32) and 5.52 h (SD=7.53) in the TAP group and difference was statistically significant (p=0.000). Mean total rescue analgesic requirement for the CE and TAP groups was 298.40 mg (SD=170.70) and 111.40 mg (SD=138.81) and the difference was also significant. Post-operative complications such as urinary retention and motor blockade were seen in 28% of CE patients, while none of the patients experienced post-operative nausea/vomiting.

Conclusions: Our study showed significant increase in duration of post-operative analgesia among TAP patients with reduced requirement of rescue analgesics and lesser post-operative complications as compared to CE patients
COMPARATIVE STUDY OF HISTOLOGICAL AND HISTOCHEMICAL PROPERTIES OF PERITONEAL MAST CELLS OF ALBINO RAT USING TWO TYPES OF FIXATIVES
Authors: NIRALA KAMTA PRASAD , GUPTA SUBHASH
Published: June 2021

Objectives: To make a comparative study of histological and histochemical properties of peritoneal mast cells in albino rat using neutral buffered formalin and formal alcohol as fixatives.

Methods: The stretch preparation from Albino rat peritoneum was made on chemically clean glass slides and immediately placed into the fixatives.

Results: With toluidine blue (pH 4.4), the mast cells stained deep purple and similar reaction was obtained with toluidine blue at pH 2. These staining reactions indicate the presence of substantial amount of heparin trisulfate, small amount of heparin monosulfate, and neutral mucopolysaccharide.

Conclusion: Heparin trisulfate is an active form of heparin and is the main constituent of the mast cell granules of the albino rat.
WHEATGRASS (TRITICUM AESTIVUM LINN.): A POTENTIAL SUBSTITUTE OF HUMAN BLOOD IN TRADITIONAL SYSTEM OF MEDICINE
Authors: CHOUDHARY SHAILJA , KAURAV HEMLATA , CHAUDHARY GITIKA
Published: June 2021

Wheatgrass (Triticum aestivum Linn.) refers to the young grass of the common wheat plant which belongs to the family Poaceae. It is known as thepowerhouse of nutrients and vitamins. The juice of wheatgrass is known as “green blood” which contains an excessive amount of chlorophyll content(70% of the total chemical constituents), antioxidants, active enzymes, vitamins, and other vital nutrients which are used to enhance lungs and heartfunction. Wheatgrass juice is also taken as a supplementary diet to boost the immune system and provide strength to the human body. From reportedstudies, it is proved that molecules of human blood hemoglobin and wheatgrass chlorophyll contain the same structure and can act as a substitute forhemoglobin in hemoglobin deficiency conditions. It is a highly nutritive plant and is used to cure diseases such as cancer, diabetes, ulcer, rheumatoidarthritis, hyperlipidemia, thalassemia, anemia, kidney stone, asthma, digestive problems, and skin diseases. Pharmacologically, wheatgrass carriesproperties such as anti-diabetic, anti-allergic, antioxidant, anti-ulcer, anticancer, hepatoprotective, cardioprotective, anti-inflammatory, and antiarthriticproperties. In this review paper, attempts have been made to provide a brief overview of wheatgrass, its pharmacological activities, andayurvedic view.
CUIDADO DE PACIENTES EM FINAL DE VIDA: o que profissionais de enfermagem expressam sobre
Authors: Silvestrin Flávia , Nunes Tayna Nayara , Braga Luiz Renato de Moraes
Published: June 2021

The perception that we have about death and dying in our society and the way it is experienced by health professionals can bring important psychic repercussions, especially for those who are closest to patients: the nursing team. Literature often suggests the creation of spaces for speech and/or discussion groups, as a care strategy for these professionals. The present study refers to a qualitative, exploratory and empirical research, whose proposal was to verify, through semi-structured interview, if nursing professionals in a Semi-Intensive Care Center have demands to work on themes related to care of end-of-life patients through an operative group and, according to the results, propose its realization. 21 professionals participated. The interviews were analyzed using the Content Analysis technique, which allowed to list five categories: Frequency; Difficulties; Coping strategies; Established links; Demands for updates and speech spaces. The results showed that the participants considered it necessary a space to talk about their experiences in the context of care for patients at the end of life, however, when it was proposed, it did not have adherence. A number of reasons can be considered about the impediments and difficulties in the implementation of a group with nursing professionals working in intensive care, as the main contingents are issues related to the profession itself, resistance, work overload, the context itself institutional and pandemic, making clear the need for further studies.
Effect of elevated temperature on the population dynamics of fall armyworm, Spodoptera frugiperda
Authors:   Department of Agricultural Entomology, Tamil Nadu Agricultural University, Coimbatore - 641003, India, Ashok K. , Balasubramani V. ,   Department of Agricultural Entomology, Tamil Nadu Agricultural University, Coimbatore - 641003, India, Kennedy J.S. ,   School of Post Graduate Studies, Tamil Nadu Agricultural University, Coimbatore - 641003, India, Geethalakshmi V. ,   Directorate of Crop Management, Tamil Nadu Agricultural University, Coimbatore - 641003, India, Jeyakumar P. ,   Department of Crop Physiology, Tamil Nadu Agricultural University, Coimbatore - 641003, India, Sathiah N. ,   Department of Agricultural Entomology, Tamil Nadu Agricultural University, Coimbatore - 641003, India
Published: June 2021

Aim: The present study was conducted to determine the growth, survival, fecundity and mortality rate of Spodoptera frugiperda in maize at elevated temperature. Methodology: Biology and life table experiments were carried out in custom made Open Top Chambers (4m x 4m x 4m size) fitted with SCADA under increasing temperature regimes viz., 32˚C, 33˚C, 34˚C, 35˚C and 36˚C. Each stage of the insects was examined daily and the fertility and life-table parameters were calculated by using TWOSEX-MS chart. Results: The overall developmental time for egg, larva, pupa and adult stages (total lifespan) at different elevated temperatures were in the order of 32˚C > 33˚C > 34˚C > 35˚C > 36˚C. The fecundity rate of S. frugiperda at different elevated temperatures were in the order of 34˚C > 33˚C > 32˚C > 35˚C > 36˚C. Interpretation: The current study confirms that the elevated temperature regimes had a positive correlation with fecundity rate upto 34˚C and negative correlation with the survival rate of S. frugiperda.
Influence of abiotic factors on stem borer incidence and species distribution in rice (Oryza sativa L.)
Authors:   Department of Agricultural Entomology, Agricultural College and Research Institute, TNAU, Coimbatore- 641 003, India, Sharmitha T. , Justin C.G.L. ,   Department of Plant Protection, Anbil Dharmalingam Agricultural College and Research Institute, TNAU, Tiruchirappalli-620 027, India, Roseleen S.S.J. ,   Department of Plant Protection, Anbil Dharmalingam Agricultural College and Research Institute, TNAU, Tiruchirappalli-620 027, India
Published: June 2021

Aim: To evaluate the effect of abiotic factors such as temperature, relative humidity, wind velocity, sunshine hours and rainfall on the distribution and relative abundance of stem borer species in rice ecosystem. Methodology: Seasonal incidence of stem borer species was monitored using light trap catches and were correlated with the weather parameters. The relative abundance of stem borer species during Kharif and Rabi was estimated based on light trap catches and larval incidence. Results: Seasonal incidence revealed the occurrence of three stem borer species (yellow stem borer, pink stem borer and dark headed borer) populations in rice ecosystem. Yellow stem borer was found to dominate in rice ecosystem during Kharif, (80.61%) whereas during Rabi, pinkstem borer was found to be dominant (72.60%) than yellow stem borer (21.92%) and dark headed borer (5.48%). Weather parameters such as temperature, rainfall and wind velocity negatively influenced the occurrence of stem borer species in rice, whereas relative humidity and sunshine hours had positive effect. Regression analysis revealed the increased effect of abiotic factors such as temperature, relative humidity and wind velocityon the population of pink stem borer against yellow stem borer and dark headed borer. Interpretation: The present study reveals that, the change in weather parameter during seasons, such as temperature (25 - 27°C), relative humidity (69 - 80 %) and wind velocity (3 - 4 km hr-1) increased the fitness of pink stem borer species population than yellow stem borer and dark headed borer species in rice ecosystem, which was evidenced by the occurrence and relative abundance of pink stem borer population during Kharif 2018 and Rabi 2019 respectively.
Degradation ability of wood decay fungi in teak (Tectona grandis L.) wood under storage condition
Authors:   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India, Sudha A. , Thiribhuvanamala G. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India, Rajamanickam S. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India
Published: June 2021

Aim: The present study was undertaken to provide basic knowledge about the teak woody biomass degradation ability of wood decay fungi. Methodology: Wood decay fungi was isolated from the decayed wood samples collected from teak wood logs. The weight loss of teak wood and moisture content were assessed under in-vitro condition by incubating the teak wood block with the isolated fungi. Further, the secretion of ligninolytic enzymes viz., laccase, lignin peroxidise (LiP) and manganese peroxidase (MnP) produced by wood decay fungi were assessed to understand their degrading ability. Results: Wood decay fungi namely, Daldinia concentrica, Ganoderma lucidum, Lenzites betulina, Ganoderma tsugae, Trametes versicolor and Schizophyllum commune, were isolated from teak wood logs as pure culture and were used for studying their degrading ability. Higher degrading percentage of 10.50 and 12.0 was recorded with L. betulina and T. versicolor inoculated wood blocks on 60th day of incubation. Similarly, the maximum moisture content of 54.45 and 50.00 percent was recorded with L. betulina and T. versicolor at 60th day of incubation in teak wood blocks. Supporting these results, L. betulina showed increased secretion of laccase, LiP and MnP enzyme activity to the level of 0.60, 0.056 and 0.26U ml-1, respectively. Interpretation: The results of the present study gives an understanding on the degrading ability of wood decay fungi which can be used to devise integrated management practices to minimise the losses under storage.
Neuroendocrine control of cocoon production in native earthworm Perionyx ceylanensis subjected to seasonal variation
Authors:   Earthworm Research Laboratory, Department of Zoology, Tripura University, Tripura-799022, India, Chaudhuri P.S. , Datta R. ,   Earthworm Research Laboratory, Department of Zoology, Tripura University, Tripura-799022, India
Published: June 2021

Aim: The aim of the present study was to observe the role of cerebral ganglionic neurosecretory cells (NSCs) during cocoon production in native earthworm species Perionyx ceylanensis subjected to amputation and seasonal variations. Methodology: Histological studies (using Aldehyde Fuchsin and Chrome Alum Haematoxylin Phloxin stain) were carried out on brain NSCs in the two groups of earthworms (Group I and Group II) maintained in earthen culture pots (2L) with cowdung as food. Group I comprised of brain amputed earthworms was subjected to observe the role of brain NSCs in production of cocoon and Group II earthworms subjected to seasonal changes in the cerebral NSCs during cocoon production. Five replications were kept for Group I (1 individual per pot) and Group II (1 pair per pot). Results: Group I debrained earthworms started to lay cocoons from the 31st day following regeneration of cerebral ganglionic type A NSCs. In group II worms the highest neurosecretory activity was registered in the cerebral type A cells, especially during monsoon coinciding with the hike of cocoon generation. Interpretation: Appearance of type A NSCs in regenerated brain and peak of type A neurosecretory cell activity during peak reproductive period of earthworm species (as indicated by peak of cocoon production) indicates the possible role of cerebral type A NSCs in cocoon laying.
Response of cotton genotypes against the incidence of Alternaria leaf blight of cotton under field conditions
Authors:   Department of Plant Pathology, ICAR-Indian Institute of Millets Research, Hyderabad-500 030, India, Rajesha G. , Nakkeeran S. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India, Indumathi T. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India, Adhipathi P. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India, Chandrasekar A. ,   Department of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore-641 003, India
Published: June 2021

Aim: To identify the resistant source present in the breeding materials against Alternaria leaf blight disease of cotton (Gossypium spp.). Methodology: Breeding entries were sown in a randomized complete block design in the experimental site. Disease intensity on each genotype at 45, 90, 135 and 180 days after sowing (DAS) were recorded from leaves of lower, middle and upper parts of plants and graded. According to 0 - 4 disease scoring scale, per cent disease index (PDI) was calculated and genotypes were categorized into different categories based on disease reaction Results: Development of Alternaria disease was noticed at early days of crop growth in few genotypes and the disease increased upto 135 days after sowing. The maximum mean per cent disease index of 41.17 and 40.06 were recorded in Br.14a (ZT)1333 and Br.14a (ZT)1332 respectively. The least PDI of 0.58 was recorded in Br.03a (ZT)1303. Disease incidence of <11.00% of was reported in 37 entries at 45 days after sowing. None of the genotypes showed apparently immune reaction, twenty-one genotypes showed resistant reaction, eleven genotypes were moderately resistant and five showed moderately susceptible reaction. Interpretation: Twenty-one breeding lines showed resistant reaction against Alternaria leaf blight disease under field conditions, however, further utilization of these lines may be carried out in breeding programmes for the development of resistant source against this disease.
The city of Tijuana as seen by the residents of Fort Irwin, California
Authors: García Chaira Sandra Cruz Aurelia , Miranda Zavala Ana María , Cruz Estrada Isaac
Published: June 2021

The objective is to analyze the perception that the residents of Fort Irwin have about the city of Tijuana. For this quantitative methodology, a survey was applied to 260 inhabitants of Fort Irwin, and the instrument consists of four dimensions: general data, characteristics, services and perception of Tijuana. Results: the elements that motivate the citizens of Fort Irwin to visit Tijuana are the weather, the variety of cultural and outdoor activities and gastronomy but the negative aspects are the insecurity and lack of cleanliness in the city. Conclusion: the factors of safety, public services and gastronomy are those that are related in greater incidence with the image of the city of Tijuana.
EDUCAÇÃO MATEMÁTICA PARA E COM IDOSOS EM TEMPOS DE PANDEMIA
Authors: Lopes Ronaldo André , Julio Rejane Siqueira , Silva Guilherme Henrique Gomes da , Cardoso Rafael Ferreira , Neves Sara Maria Fagundes Conti
Published: June 2021

O projeto de extensão Conversas Matemáticas desenvolve atividades pedagógicas envolvendo matemática para e com pessoas idosas na Universidade Federal de Alfenas. Neste artigo, abordamos novas formas de ser e compor um projeto extensionista em tempos de pandemia, considerando o desenvolvimento do Conversas Matemáticas no ano pandêmico de 2020, bem como as avaliações das participantes sobre o projeto e as expectativas em relação à edição de 2021 do projeto. Em 2020, a equipe elaborou e desenvolveu vinte atividades remotamente para e com dezessete idosas, utilizando um grupo de Whatsapp para as interações e a entrega de atividades em domicílio, via correio. Também foram realizadas ligações de áudio para manter o contato com as idosas e para conversar sobre as vivências pessoais delas durante a pandemia. Como resultado, as participantes apontam a importância do projeto, que possibilitou que elas se mantivessem ativas e permitiu o senso de pertencimento ao grupo, proporcionando alegria e aprendizado. Além disso, as idosas destacaram aspectos relevantes para a execução do projeto em 2021, com interesse pela continuidade das atividades. Concluímos que o projeto tem impactado positivamente a vida das idosas, viabilizando a inclusão social e a interação dialógica.
ANÁLISE DE SAZONALIDADE NA SÉRIE DOS PREÇOS MÉDIOS DA BANANA E TOMATE CONSTANTES NA CESTA BÁSICA DO MUNICÍPIO DE VITÓRIA DA CONQUISTA, BA
Authors: De Carvalho Delza Rodrigues , Santos Josefa de Lisboa , Amaral Marcelo Santos , Santana Júnior Gildásio
Published: June 2021

Este artigo tem por objetivo estudar o comportamento sazonal da série dos preços médios do tomate e da banana da prata, bem como os seus impactos nos gastos da Cesta básica do Município de Vitória da Conquista, utilizando a Análise de Séries Temporais, por meio dos modelos clássico aditivo e multiplicativo, em planilha eletrônica de Excel. Os dados foram fornecidos pelo Programa de Indicadores Econômicos da UESB e compreendem os preços médios mensais coletados entre outubro de 2014 e julho de 2019. Nos resultados apresentados pelos modelos, houve influência da sazonalidade, apresentando quedas nos preços médios para os meses de setembro, outubro, novembro e dezembro, e aumentos nos preços para os meses de fevereiro, marco, abril e maio. A variação dos preços médios de alguns dos produtos que compõem a cesta básica é influenciada pela mudança climática que determina as melhores épocas para plantio e colheita no Brasil. Conclui-se,  destacando a importância de se fazer uma análise sazonal, não só para a série de produtos que impactam no custo da cesta básica, como para todas as outras séries econômicas semelhantes.
SISTEMAS AVALIATIVOS E O ENSINO REMOTO EMERGENCIAL
Authors: Jaime Maria Clara Rabelo , De Oliveira Ellen Eloise , Domingues Soraya Correa
Published: June 2021

A partir da declaração da OMS sobre a pandemia do Coronavírus, diferentes estratégias buscaram minimizar o contágio do vírus com medidas profiláticas, como o distanciamento social. Neste contexto, a escola precisou adaptar o processo de ensino presencial para remoto emergencial, alterando os sistemas metodológicos e avaliativos para atender as atuais demandas. Com isso, o seguinte artigo buscou analisar os modelos avaliativos adotados por nove instituições de ensino básico da cidade de Curitiba-PR e região metropolitana, entre privadas e públicas, objetivando apresentar seus respectivos métodos e compreender estratégias adotadas. Como caminho metodológico foi realizada análise qualitativa expositiva, através de entrevista semi-estruturada realizada de forma remota com professores de educação física. Por fim, pode-se considerar que existem diferentes modelos avaliativos que estão em consonância com o método usado pela escola no processo ensino-aprendizagem remoto e particularidades diversas são evidentes, relacionadas à inserção tecnológica no ambiente escolar, a não aferição da aprendizagem por verificação e exames, e entre os sistemas escolares e a ampliação ou limitação desses métodos. Conclui-se que, que as inovações do sistema avaliativo são alicerce para argumentações e melhorias no sistema tradicional, sua exposição evidencia a necessidade de possibilidades que auxilia a travessia desse momento da forma mais equilibrada possível.
IMPLANTAÇÃO DA EXTENSÃO UNIVERSITÁRIA EM UM CURSO DE DIREITO EM ATENDIMENTO À RESOLUÇÃO CNE/CES Nº. 7/2018
Authors: Jacob Alexandre
Published: June 2021

Trata-se de relato de experiência da implantação de atividades de extensão universitária em um curso de Direito de uma faculdade no leste mineiro com o objetivo de tornar fática a Resolução CNE/CES nº. 7/2018 que prevê a obrigatoriedade para a extensão universitária em todos os cursos de graduação em 2021. Com fundamento na Lei de Diretrizes e Bases da Educação Nacional e no Projeto Pedagógico do Curso, as atividades de extensão visam integrar a Universidade à Comunidade. Durante a implantação no ano de 2020 fomos surpreendidos com a quarentena em razão da pandemia por Covid-19, o que poderia impactar negativamente nos objetivos, contudo, com a adoção de metodologias participativas foi possível obter resultados acima do esperado, com a adesão de quase todos os alunos do curso de Direito e uma pluralidade de atividades de extensão universitária desenvolvidas em meio a uma crise sanitária e econômica, o que leva à conclusão que a implantação da extensão universitária atende às determinações legais e aos seus objetivos de forma positiva e que as dificuldades impostas pela quarentena não foram suficientes para desanimar os alunos das ações relacionadas aos Direitos Humanos, essenciais, especialmente nesses períodos de crise.