bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary figures 1-9 Supplementary Table 1 from Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2
Authors: Malakar Pushkar , Stein Ilan , Saragovi Amijai , Winkler Roni , Stern-Ginossar Noam , Berger Michael , Pikarsky Eli , Karni Rotem
Published: April 2023

Supplementary Information: Figure S1: MALAT1 affects cancer glucose metabolism Figure S2: Glucose metabolism in HCC cell lines with MALAT1 knockdown. Figure S3: Regulation of TCF7L2 protein expression by MALAT1 in HCC cell lines. Figure S4: A non-phosphorylatable mutant of 4EBP1 inhibits TCF7L2 protein expression and expression of glycolytic genes. Figure S5: SRSF1 regulates TCF7L2 levels post-transcriptionally. Figure S6: TCF7L2 modulates glucose metabolism in a HCC cell line. Figure S7: MALAT1 and TCF7L2 regulate gluconeogenesis through the same pathway. Figure S8: Oncogenic properties of HCC cell lines with TCF7L2 knockdown. Figure S9: TCF7L2 protein, Gluconeogenesis and Glycolytic enzyme expression in livers from mouse HCC model Mdr2-/-. Table S1: List and sequences of shRNAs, siRNAs and PCR primers used in the paper
Supplemental Figure Legends from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Legends for Supplemental Figures 1-8
Supplement Table 1 from Diabetes Treatments and Risks of Adverse Breast Cancer Outcomes among Early-Stage Breast Cancer Patients: A SEER-Medicare Analysis
Authors: Chen Lu , Chubak Jessica , Boudreau Denise M. , Barlow William E. , Weiss Noel S. , Li Christopher I.
Published: April 2023

Characteristics of women included in the study and women not eligible due to enrollment requirement
Figure S7 from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Restoring GFR-signaling in mILC1-shFOXOs cells is insufficient to rescue cell proliferation and stress kinase induction.
Supplementary Information from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer
Authors: Cox Orla T. , Edmunds Shelley J. , Simon-Keller Katja , Li Bo , Moran Bruce , Buckley Niamh E. , Bustamante-Garrido Milan , Healy Nollaig , O'Flanagan Ciara H. , Gallagher William M. , Kennedy Richard D. , Bernards René , Caldas Carlos , Chin Suet-Feung , Marx Alexander , O'Connor Rosemary
Published: April 2023

Supplementary Methods
Supplementary Figure 6 from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer
Authors: Cox Orla T. , Edmunds Shelley J. , Simon-Keller Katja , Li Bo , Moran Bruce , Buckley Niamh E. , Bustamante-Garrido Milan , Healy Nollaig , O'Flanagan Ciara H. , Gallagher William M. , Kennedy Richard D. , Bernards René , Caldas Carlos , Chin Suet-Feung , Marx Alexander , O'Connor Rosemary
Published: April 2023

Related to Figure 6: Western blots and immunofluorescence images of PDLIM2 and b-catenin phospho-Ser675 expression and localization in BT549 cells overexpressing HA-PDLIM2 are included. Graph depicting measurements of cell migration in HA-PDLIM2-expressing BT549 is shown. The effects of suppression of PDLIM2 on b-catenin and b1-integrin levels in HCC1806 and MDA-MB-231-LUC2 are shown. Further analyses of effects of loss of adhesion and also, serum starvation, on PDLIM2 and active b-catenin subcellular localization in TN Breast cell lines are also shown.
Figure S3 from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Immunohistochemistry analysis of mILC1-shFOXOs tumors & primary tumor size upon detection of metastasis.
Figure S1 from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Immunohistochemistry analysis of mILC1-iFOXO3.A3 tumors & primary tumor size upon detection of metastasis.
Supplementary Figure 1 from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer
Authors: Cox Orla T. , Edmunds Shelley J. , Simon-Keller Katja , Li Bo , Moran Bruce , Buckley Niamh E. , Bustamante-Garrido Milan , Healy Nollaig , O'Flanagan Ciara H. , Gallagher William M. , Kennedy Richard D. , Bernards René , Caldas Carlos , Chin Suet-Feung , Marx Alexander , O'Connor Rosemary
Published: April 2023

Related to Figure 1: Includes additional images of immunohistochemical staining and scores of PDLIM2 expression in tumor and stroma of Breast Cancer TMA samples.
Supplementary Data from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer
Authors: Cox Orla T. , Edmunds Shelley J. , Simon-Keller Katja , Li Bo , Moran Bruce , Buckley Niamh E. , Bustamante-Garrido Milan , Healy Nollaig , O'Flanagan Ciara H. , Gallagher William M. , Kennedy Richard D. , Bernards René , Caldas Carlos , Chin Suet-Feung , Marx Alexander , O'Connor Rosemary
Published: April 2023

Supplementary Table I (RPPA) and Table II (Gene expression data).
Supplementary Materials and Methods from Novel SEC61G–EGFR Fusion Gene in Pediatric Ependymomas Discovered by Clonal Expansion of Stem Cells in Absence of Exogenous Mitogens
Authors: Servidei Tiziana , Meco Daniela , Muto Valentina , Bruselles Alessandro , Ciolfi Andrea , Trivieri Nadia , Lucchini Matteo , Morosetti Roberta , Mirabella Massimiliano , Martini Maurizio , Caldarelli Massimo , Lasorella Anna , Tartaglia Marco , Riccardi Riccardo
Published: April 2023

Description of additional methods and procedures used in the study; list of primers and antibodies used.
Supplementary Table S9, S10 from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Authors: Wang Lei , Felts Sara J. , Van Keulen Virginia P. , Scheid Adam D. , Block Matthew S. , Markovic Svetomir N. , Pease Larry R. , Zhang Yuji
Published: April 2023

Table S9: The information of lncRNAs associated with H3K4me3 and H3K36me3 (including immune-associated, translation-associated, and differentially expressed lncRNAs), i.e., the number of lncRNAs with H3K4me3 and H3K36me3 peaks in the region of +/- 3 kb transcription start sites of lncRNAs in CD4+, CD8+, and CD14+ PBCs respectively. Table S10: The information of RNA-binding proteins associated with the 16 most highly expressed lncRNAs in CD4+, CD8+, and CD14+ PBCs.
Supplementary Table S8 from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Authors: Wang Lei , Felts Sara J. , Van Keulen Virginia P. , Scheid Adam D. , Block Matthew S. , Markovic Svetomir N. , Pease Larry R. , Zhang Yuji
Published: April 2023

The information of the trans-regulatory lncRNAs associated with PD-1 checkpoint pathways in T cells (CD4+ and CD8+ PBCs).
Supplementary Table S6 from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Authors: Wang Lei , Felts Sara J. , Van Keulen Virginia P. , Scheid Adam D. , Block Matthew S. , Markovic Svetomir N. , Pease Larry R. , Zhang Yuji
Published: April 2023

The information of the trans-regulatory lncRNAs associated with immune responses and 3 mRNA translation pathways in CD8+ PBC.
Supplementary Figure 1 from Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination
Authors: Aryal Neeraj K. , Pant Vinod , Wasylishen Amanda R. , Rimel Bobbie J. , Baseler Laura , El-Naggar Adel K. , Mutch David G. , Goodfellow Paul J. , Arur Swathi , Lozano Guillermina
Published: April 2023

Tumors and Metastasis in KRas+/LA1;Dicer+/2SD mice
Video 2. Neurosurgical case visualization with SlicerDMRI from SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research
Authors: Norton Isaiah , Essayed Walid Ibn , Zhang Fan , Pujol Sonia , Yarmarkovich Alex , Golby Alexandra J. , Kindlmann Gordon , Wassermann Demian , Estepar Raul San Jose , Rathi Yogesh , Pieper Steve , Kikinis Ron , Johnson Hans J. , Westin Carl-Fredrik , O'Donnell Lauren J.
Published: April 2023

Video 2. This video shows visualization of multi-fiber diffusion MRI tractography for a neurosurgical patient with a left insular glioblastoma.
Suppl Figure 7 from BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC
Authors: Leonard Brandon , Brand Toni M. , O'Keefe Rachel A. , Lee Eliot D. , Zeng Yan , Kemmer Jacquelyn D. , Li Hua , Grandis Jennifer R. , Bhola Neil E.
Published: April 2023

Evaluation of RTK and Ki67 expression in PDX6282 treated with cetuximab and JQ1
Supplementary Materials from PADI2-Mediated Citrullination Promotes Prostate Cancer Progression
Authors: Wang Lin , Song Guanhua , Zhang Xiang , Feng Tingting , Pan Jihong , Chen Weiwen , Yang Muyi , Bai Xinnuo , Pang Yu , Yu Jindan , Han Jinxiang , Han Bo
Published: April 2023

Legends for Supplementary Figures and Tables.
Supplemental Table 1 from PADI2-Mediated Citrullination Promotes Prostate Cancer Progression
Authors: Wang Lin , Song Guanhua , Zhang Xiang , Feng Tingting , Pan Jihong , Chen Weiwen , Yang Muyi , Bai Xinnuo , Pang Yu , Yu Jindan , Han Jinxiang , Han Bo
Published: April 2023

Primer sequence used in this study
Figure S5. from PADI2-Mediated Citrullination Promotes Prostate Cancer Progression
Authors: Wang Lin , Song Guanhua , Zhang Xiang , Feng Tingting , Pan Jihong , Chen Weiwen , Yang Muyi , Bai Xinnuo , Pang Yu , Yu Jindan , Han Jinxiang , Han Bo
Published: April 2023

PADI2 inhibition decreases the transcriptional activity of PSA. Treatment with siPADI2 or Cl-amidine suppresses the transcriptional activity of PSA in LNCaP and C4-2B cells.
Figure S4 from The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
Authors: Weissmann Simon , Cloos Paul A. , Sidoli Simone , Jensen Ole N. , Pollard Steven , Helin Kristian
Published: April 2023

Supplementary Figure S4 depicts global gene expression changes in G144 cells (WT and CIC-KO) in response to MEK inhibition as well as expression changes after HDAC inhibition in combination with MEK inhibition at selected target genes.
Combined supplementary figures from The Canonical Wnt Pathway Drives Macropinocytosis in Cancer
Authors: Redelman-Sidi Gil , Binyamin Anna , Gaeta Isabella , Palm Wilhelm , Thompson Craig B. , Romesser Paul B. , Lowe Scott W. , Bagul Mukta , Doench John G. , Root David E. , Glickman Michael S.
Published: April 2023

Figure S1: Activation of the canonical Wnt pathway stimulates macropinocytic BCG uptake; Figure S2: Macropinocytosis Assay Validation; Figure S3: rWnt3A increased macropinocytosis in a Ras-wild type cell line; Figure S4: Expression of E(beta)P increases macropinocytosis in a Ras-wild type cell line; Figure S5: Activation of the Wnt pathway stimulates macropinocytosis in Ras-wild type cell lines; Figure S6: Wnt Pathway Inhibitors inhibit macropinocytic uptake of BCG; Figure S7: Treatment with ICG001 decreases macropinocytosis in a Ras-mutant cell line; Figure S8: WNT pathway activation is an essential cofactor in Ras driven macropinocytosis; Figure S9: Expression of pQCXIP-AXIN1 decreases macropinocytosis in a Ras-wild type cell line; Figure S10: Wnt pathway activation stimulates macropinocytosis and bacterial uptake in the mouse colon;
Supplementary Figures S1-5, Tables S1-3, Captions for Movies S1-3 from An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells
Authors: Freedman Joshua D. , Duffy Margaret R. , Lei-Rossmann Janet , Muntzer Alice , Scott Eleanor M. , Hagel Joachim , Campo Leticia , Bryant Richard J. , Verrill Clare , Lambert Adam , Miller Paul , Champion Brian R. , Seymour Leonard W. , Fisher Kerry D.
Published: April 2023

Supplementary Files detailing additional experiments supporting the conclusions of the manuscript, including additional activation, cytotoxicity, and cytokine analyses. Supplementary tables contain more details on characterisation of patient biopsies and virus stocks used in the study.
Table S1 from miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes
Authors: Hu Tianxiang , Chong Yating , Lu Sumin , Wang Rebecca , Qin Haiyan , Silva Jeane , Kitamura Eiko , Chang Chang-Sheng , Hawthorn LesleyAnn , Cowell John K.
Published: April 2023

Summary of predicted targets of miR-339-5p using TargetScan, ,iRDB and miRWalk
Table S1 from LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates
Authors: Purcell James W. , Tanlimco Sonia G. , Hickson Jonathan , Fox Melvin , Sho Mien , Durkin Lisa , Uziel Tamar , Powers Rick , Foster Kelly , McGonigal Thomas , Kumar Subashri , Samayoa Josue , Zhang Dong , Palma Joann P. , Mishra Sasmita , Hollenbaugh Diane , Gish Kurt , Morgan-Lappe Susan E. , Hsi Eric D. , Chao Debra T.
Published: April 2023

Cross species binding and tolerability of ABBV-085.
Table S7 from A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk
Authors: Lu Yingchang , Beeghly-Fadiel Alicia , Wu Lang , Guo Xingyi , Li Bingshan , Schildkraut Joellen M. , Im Hae Kyung , Chen Yian A. , Permuth Jennifer B. , Reid Brett M. , Teer Jamie K. , Moysich Kirsten B. , Andrulis Irene L. , Anton-Culver Hoda , Arun Banu K. , Bandera Elisa V. , Barkardottir Rosa B. , Barnes Daniel R. , Benitez Javier , Bjorge Line , Brenton James , Butzow Ralf , Caldes Trinidad , Caligo Maria A. , Campbell Ian , Chang-Claude Jenny , Claes Kathleen B.M. , Couch Fergus J. , Cramer Daniel W. , Daly Mary B. , deFazio Anna , Dennis Joe , Diez Orland , Domchek Susan M. , Dörk Thilo , Easton Douglas F. , Eccles Diana M. , Fasching Peter A. , Fortner Renée T. , Fountzilas George , Friedman Eitan , Ganz Patricia A. , Garber Judy , Giles Graham G. , Godwin Andrew K. , Goldgar David E. , Goodman Marc T. , Greene Mark H. , Gronwald Jacek , Hamann Ute , Heitz Florian , Hildebrandt Michelle A.T. , Høgdall Claus K. , Hollestelle Antoinette , Hulick Peter J. , Huntsman David G. , Imyanitov Evgeny N. , Isaacs Claudine , Jakubowska Anna , James Paul , Karlan Beth Y. , Kelemen Linda E. , Kiemeney Lambertus A. , Kjaer Susanne K. , Kwong Ava , Le Nhu D. , Leslie Goska , Lesueur Fabienne , Levine Douglas A. , Mattiello Amalia , May Taymaa , McGuffog Lesley , McNeish Iain A. , Merritt Melissa A. , Modugno Francesmary , Montagna Marco , Neuhausen Susan L. , Nevanlinna Heli , Nielsen Finn C. , Nikitina-Zake Liene , Nussbaum Robert L. , Offit Kenneth , Olah Edith , Olopade Olufunmilayo I. , Olson Sara H. , Olsson Håkan , Osorio Ana , Park Sue K. , Parsons Michael T. , Peeters Petra H.M. , Pejovic Tanja , Peterlongo Paolo , Phelan Catherine M. , Pujana Miquel Angel , Ramus Susan J. , Rennert Gad , Risch Harvey , Rodriguez Gustavo C. , Rodríguez-Antona Cristina , Romieu Isabelle , Rookus Matti A. , Rossing Mary Anne , Rzepecka Iwona K. , Sandler Dale P. , Schmutzler Rita K. , Setiawan Veronica W. , Sharma Priyanka , Sieh Weiva , Simard Jacques , Singer Christian F. , Song Honglin , Southey Melissa C. , Spurdle Amanda B. , Sutphen Rebecca , Swerdlow Anthony J. , Teixeira Manuel R. , Teo Soo H. , Thomassen Mads , Tischkowitz Marc , Toland Amanda E. , Trichopoulou Antonia , Tung Nadine , Tworoger Shelley S. , van Rensburg Elizabeth J. , Vanderstichele Adriaan , Vega Ana , Edwards Digna Velez , Webb Penelope M. , Weitzel Jeffrey N. , Wentzensen Nicolas , White Emily , Wolk Alicja , Wu Anna H. , Yannoukakos Drakoulis , Zorn Kristin K. , Gayther Simon A. , Antoniou Antonis C. , Berchuck Andrew , Goode Ellen L. , Chenevix-Trench Georgia , Sellers Thomas A. , Pharoah Paul D.P. , Zheng Wei , Long Jirong
Published: April 2023

Variants with P < 5E-8 either in BCAC or OCAC between 42,836,399 and 44,910,520 on the chromosome 17.
Table S5 from A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk
Authors: Lu Yingchang , Beeghly-Fadiel Alicia , Wu Lang , Guo Xingyi , Li Bingshan , Schildkraut Joellen M. , Im Hae Kyung , Chen Yian A. , Permuth Jennifer B. , Reid Brett M. , Teer Jamie K. , Moysich Kirsten B. , Andrulis Irene L. , Anton-Culver Hoda , Arun Banu K. , Bandera Elisa V. , Barkardottir Rosa B. , Barnes Daniel R. , Benitez Javier , Bjorge Line , Brenton James , Butzow Ralf , Caldes Trinidad , Caligo Maria A. , Campbell Ian , Chang-Claude Jenny , Claes Kathleen B.M. , Couch Fergus J. , Cramer Daniel W. , Daly Mary B. , deFazio Anna , Dennis Joe , Diez Orland , Domchek Susan M. , Dörk Thilo , Easton Douglas F. , Eccles Diana M. , Fasching Peter A. , Fortner Renée T. , Fountzilas George , Friedman Eitan , Ganz Patricia A. , Garber Judy , Giles Graham G. , Godwin Andrew K. , Goldgar David E. , Goodman Marc T. , Greene Mark H. , Gronwald Jacek , Hamann Ute , Heitz Florian , Hildebrandt Michelle A.T. , Høgdall Claus K. , Hollestelle Antoinette , Hulick Peter J. , Huntsman David G. , Imyanitov Evgeny N. , Isaacs Claudine , Jakubowska Anna , James Paul , Karlan Beth Y. , Kelemen Linda E. , Kiemeney Lambertus A. , Kjaer Susanne K. , Kwong Ava , Le Nhu D. , Leslie Goska , Lesueur Fabienne , Levine Douglas A. , Mattiello Amalia , May Taymaa , McGuffog Lesley , McNeish Iain A. , Merritt Melissa A. , Modugno Francesmary , Montagna Marco , Neuhausen Susan L. , Nevanlinna Heli , Nielsen Finn C. , Nikitina-Zake Liene , Nussbaum Robert L. , Offit Kenneth , Olah Edith , Olopade Olufunmilayo I. , Olson Sara H. , Olsson Håkan , Osorio Ana , Park Sue K. , Parsons Michael T. , Peeters Petra H.M. , Pejovic Tanja , Peterlongo Paolo , Phelan Catherine M. , Pujana Miquel Angel , Ramus Susan J. , Rennert Gad , Risch Harvey , Rodriguez Gustavo C. , Rodríguez-Antona Cristina , Romieu Isabelle , Rookus Matti A. , Rossing Mary Anne , Rzepecka Iwona K. , Sandler Dale P. , Schmutzler Rita K. , Setiawan Veronica W. , Sharma Priyanka , Sieh Weiva , Simard Jacques , Singer Christian F. , Song Honglin , Southey Melissa C. , Spurdle Amanda B. , Sutphen Rebecca , Swerdlow Anthony J. , Teixeira Manuel R. , Teo Soo H. , Thomassen Mads , Tischkowitz Marc , Toland Amanda E. , Trichopoulou Antonia , Tung Nadine , Tworoger Shelley S. , van Rensburg Elizabeth J. , Vanderstichele Adriaan , Vega Ana , Edwards Digna Velez , Webb Penelope M. , Weitzel Jeffrey N. , Wentzensen Nicolas , White Emily , Wolk Alicja , Wu Anna H. , Yannoukakos Drakoulis , Zorn Kristin K. , Gayther Simon A. , Antoniou Antonis C. , Berchuck Andrew , Goode Ellen L. , Chenevix-Trench Georgia , Sellers Thomas A. , Pharoah Paul D.P. , Zheng Wei , Long Jirong
Published: April 2023

Genes coregulated in predicted expression at 2q31.1, 9p22.3, 17q21.31 and 17q21.32.
Figure S5 from Glycoprotein nmb Is Exposed on the Surface of Dormant Breast Cancer Cells and Induces Stem Cell–like Properties
Authors: Chen Chen , Okita Yukari , Watanabe Yukihide , Abe Fumie , Fikry Muhammad Ali , Ichikawa Yumu , Suzuki Hiroyuki , Shibuya Akira , Kato Mitsuyasu
Published: April 2023

Genes expression levels in 2D or 3D-cultured 4T1 cells and 4T1 tumors, and secondary tumorigenicity of cell surface-GPNMBlow/high 4T1 tumor cells.
Figure S1 from Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma
Authors: Li Binghao , Wang Zhan , Wu Hao , Xue Mingfeng , Lin Peng , Wang Shengdong , Lin Nong , Huang Xin , Pan Weibo , Liu Meng , Yan Xiaobo , Qu Hao , Sun Lingling , Li Hengyuan , Wu Yan , Teng Wangsiyuan , Wang Zenan , Zhou Xingzhi , Chen Huabiao , Poznansky Mark C. , Ye Zhaoming
Published: April 2023

Supplementary figure S1. CXCL12 promotes cell proliferation and migration via CXCR4.
Supplementary Figure S1-S9 from Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer
Authors: Su Wenmei , Feng Shumei , Chen Xiuyuan , Yang Xia , Mao Rui , Guo Chunfang , Wang Zhuwen , Thomas Dafydd G. , Lin Jules , Reddy Rishindra M. , Orringer Mark B. , Chang Andrew C. , Yang Zhixiong , Beer David G. , Chen Guoan
Published: April 2023

Supplementary Figures S1-S9. S1: MIR22HG expression in lung cancer. S2: MIR22HG expression in lung cancer cell lines. S3: Changing of cell proliferation, colony formation, migration and invasion after MIR22HG knockdown in lung cancers. S4: Western blot showing the changing of AKT, ERK1/2 and STAT3 proteins after MIR22HG siRNA treatment. S5: MIR22HG interacts with YBX1 protein and the correlation of MIR22HG, MET, YBX1 and p21. S6: P21 plays an oncogenic role in promoting tumor cell proliferation, anti-apoptosis and senescence. S7: Genes negatively correlated to MIR22HG are involved in cell cycle/proliferation regulation in primary lung cancer. S8: MIR22HG, CDKN1A (p21), YBX1 and MET mRNA expression in primary tumors and correlation on different lung RNA-seq datasets. S9: Higher expression of p21 mRNA Is related to poor patient survival and p21 protein is co-expressed with Ki-67 in a subset of tumors.
Supplementary Methods & Figure Legends from Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
Authors: Moses Michael A. , Kim Yeong Sang , Rivera-Marquez Genesis M. , Oshima Nobu , Watson Matthew J. , Beebe Kristin E. , Wells Catherine , Lee Sunmin , Zuehlke Abbey D. , Shao Hao , Bingman William E. , Kumar Vineet , Malhotra Sanjay V. , Weigel Nancy L. , Gestwicki Jason E. , Trepel Jane B. , Neckers Leonard M.
Published: April 2023

A Word file that contains Supplementary Methods & Figure Legends
Table S3 from Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult
Authors: Yao Yuxiao , Sun Shaoyang , Wang Jingjing , Fei Fei , Dong Zhaoru , Ke Ai-Wu , He Ruoyu , Wang Lei , Zhang Lili , Ji Min-Biao , Li Qiang , Yu Min , Shi Guo-Ming , Fan Jia , Gong Zhiyuan , Wang Xu
Published: April 2023

List of absolute amounts of selected lipid species in 6 dpf control, Tg(Myc), Tg(Kras), and Tg(Myc&Kras) larvae
Table S2 from Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult
Authors: Yao Yuxiao , Sun Shaoyang , Wang Jingjing , Fei Fei , Dong Zhaoru , Ke Ai-Wu , He Ruoyu , Wang Lei , Zhang Lili , Ji Min-Biao , Li Qiang , Yu Min , Shi Guo-Ming , Fan Jia , Gong Zhiyuan , Wang Xu
Published: April 2023

List of raw data of complete lipidomic mass spectrometry data
Table S1 from Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult
Authors: Yao Yuxiao , Sun Shaoyang , Wang Jingjing , Fei Fei , Dong Zhaoru , Ke Ai-Wu , He Ruoyu , Wang Lei , Zhang Lili , Ji Min-Biao , Li Qiang , Yu Min , Shi Guo-Ming , Fan Jia , Gong Zhiyuan , Wang Xu
Published: April 2023

Tabulated information about the 209 clinical HCC samples and their donors
Figure S2 from Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
Authors: Moses Michael A. , Kim Yeong Sang , Rivera-Marquez Genesis M. , Oshima Nobu , Watson Matthew J. , Beebe Kristin E. , Wells Catherine , Lee Sunmin , Zuehlke Abbey D. , Shao Hao , Bingman William E. , Kumar Vineet , Malhotra Sanjay V. , Weigel Nancy L. , Gestwicki Jason E. , Trepel Jane B. , Neckers Leonard M.
Published: April 2023

Effects of biotinylated-C86 on binding of purified Hsp40/Hsp70/Hsp90 protein; effect of 17-AAG on FL-AR/ARv7 protein; cell lysate inputs for Figure 2
Supplementary Figures and methods from Canonical Wnt Signaling Remodels Lipid Metabolism in Zebrafish Hepatocytes following Ras Oncogenic Insult
Authors: Yao Yuxiao , Sun Shaoyang , Wang Jingjing , Fei Fei , Dong Zhaoru , Ke Ai-Wu , He Ruoyu , Wang Lei , Zhang Lili , Ji Min-Biao , Li Qiang , Yu Min , Shi Guo-Ming , Fan Jia , Gong Zhiyuan , Wang Xu
Published: April 2023

The supplementary materials including: supplementary figures about human HCC sample, zebrafish liver immunostaining, transgenesis, TCGA database analysis, cell behavior, UPLC chromatograms; supplementary table list and real-time RT-PCR primers; additional methodological details
Figure S4 from EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma
Authors: An Zhenyi , Knobbe-Thomsen Christiane B. , Wan Xiaohua , Fan Qi Wen , Reifenberger Guido , Weiss William A.
Published: April 2023

Western blotting of IκB and p-IκB from protein lysates of U87 cells expressing EGFR, EGFRvIII, or both genes.
Supplemental Figures S1-S5 from Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations
Authors: Sowalsky Adam G. , Ye Huihui , Bhasin Manoj , Van Allen Eliezer M. , Loda Massimo , Lis Rosina T. , Montaser-Kouhsari Laleh , Calagua Carla , Ma Fen , Russo Joshua W. , Schaefer Rachel J. , Voznesensky Olga S. , Zhang Zhenwei , Bubley Glenn J. , Montgomery Bruce , Mostaghel Elahe A. , Nelson Peter S. , Taplin Mary-Ellen , Balk Steven P.
Published: April 2023

Figure S1: Assessment for neuroendocrine features by histology and IHC; Figure S2: Scatter plots depicting relationships between the 267-gene AR activity ssGSEA score and the 131-gene proliferation ssGSEA score for multiple genesets; Figure S3: Plots depicting correlations with AR activity ssGSEA score, and assessing GR expression; Figure S4: Segmented read depth array CGH-style plots for chromosomes showing alterations to cancer-related genes; Figure S5: Euler diagrams depicting shared and distinct somatic genomic events for cases 003, 007, 501, 503, 506, 507, 509, 512, and 520.
Table S3 from Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor
Authors: Matsunaga Naoya , Ogino Takashi , Hara Yukinori , Tanaka Takahiro , Koyanagi Satoru , Ohdo Shigehiro
Published: April 2023

KEGG classifications of the time-dependently expressed genes in ALDH-negative 4T1 cells
Supplementary Data from Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer
Authors: Srinivasan Supriya , Totiger Tulasigeri , Shi Chanjuan , Castellanos Jason , Lamichhane Purushottam , Dosch Austin R. , Messaggio Fanuel , Kashikar Nilesh , Honnenahally Kumaraswamy , Ban Yuguang , Merchant Nipun B. , VanSaun Michael , Nagathihalli Nagaraj S.
Published: April 2023

Supplementary Materials and Methods
Figure S4 from Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer
Authors: Srinivasan Supriya , Totiger Tulasigeri , Shi Chanjuan , Castellanos Jason , Lamichhane Purushottam , Dosch Austin R. , Messaggio Fanuel , Kashikar Nilesh , Honnenahally Kumaraswamy , Ban Yuguang , Merchant Nipun B. , VanSaun Michael , Nagathihalli Nagaraj S.
Published: April 2023

Figure S4 shows CREB shRNA and xenografts data
Fig. S11-S13 from Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor
Authors: Matsunaga Naoya , Ogino Takashi , Hara Yukinori , Tanaka Takahiro , Koyanagi Satoru , Ohdo Shigehiro
Published: April 2023

Supplementary Fig. 11 Unedited full blots of Fig. 3B. Supplementary Fig. 12 Unedited full blots of Fig. 4A. Supplementary Fig. 13 Unedited full blots of Fig. 4B.
Fig. S1-S3 from Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor
Authors: Matsunaga Naoya , Ogino Takashi , Hara Yukinori , Tanaka Takahiro , Koyanagi Satoru , Ohdo Shigehiro
Published: April 2023

Supplementary Fig. 1 shows the tumor formation by ALDH-positive or ALDH-negative 4T1 cells implanted in BALB/c female mice. Supplementary Fig. 2 shows the the temporal mRNA expression profile of Aldh6a1 in 4T1 tumor implanted in BALB/c female mice. Supplementary Fig. 3 shows the preparation of Aldh3a1 down-regulated 4T1 cells.
Supplementary Tables from RAS–MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma
Authors: Eleveld Thomas F. , Schild Linda , Koster Jan , Zwijnenburg Danny A. , Alles Lindy K. , Ebus Marli E. , Volckmann Richard , Tijtgat Godelieve A. , van Sluis Peter , Versteeg Rogier , Molenaar Jan J.
Published: April 2023

Supplementary Table 1: Public datasets used in this study, Supplementary Table 2: gRNA sequences against CIC, NF1 and DMD, Supplementary Table 3: Primers used for RT-qPCR experiments, Supplementary Table 4: Genes differentially expressed in the various model systems, Supplementary Table 5: Enrichment analysis of Hallmark gene sets , Supplementary Table 6: Statistical analysis of the role of RAS-MAPK activation in survival, Supplementary Table 7: Known RAS-MAPK activating mutations in our tumor series
Supplementary Figures from RAS–MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma
Authors: Eleveld Thomas F. , Schild Linda , Koster Jan , Zwijnenburg Danny A. , Alles Lindy K. , Ebus Marli E. , Volckmann Richard , Tijtgat Godelieve A. , van Sluis Peter , Versteeg Rogier , Molenaar Jan J.
Published: April 2023

Supplementary Figure 1: RAS-MAPK activation on the protein level is related to mutation status, Supplementary Figure 2: Differentially expressed genes between the experimental systems used for signature generation, Supplementary Figure 3: Differences in signature scores between RAS-MAPK mutated and non-mutated cell lines, Supplementary Figure 4: Expression of our gene signature relates to mutation status and compound sensitivity in a panel of neuroblastoma cell lines, Supplementary Figure 5: Hierarchical clustering of expression of our signature genes in sets of primary neuroblastoma tumors, Supplementary Figure 6: The effect of RAS-MAPK activation on Progress Free Survival, Supplementary Figure 7: The effect of RAS-MAPK activation on Overall Survival within the different tumor stages, Supplementary Figure 8: The relationship between RAS-MAPK activation, MYCN amplification and the presence of mutations in ATRX and TERT, Supplementary Figure 9: RAS-MAPK signature scores in primary tumors based on the presence of activating mutations, Supplementary Figure 10: Focal deletion of CIC in an additional tumor, Supplementary Figure 11: Overexpression of mutant PHOX2B or deletion of DMD does not induce expression of RAS-MAPK signature genes in cell lines, Supplementary Figure 12: Overexpression of mutant PHOX2B or deletion of DMD does not induce expression of RAS-MAPK signature genes in xenograft tumors and does not affect survival, Supplementary Figure 13: Mutations in CIC are associated with resistance of cell lines to the MEK inhibitor Trametinib
Table S9 from Zebrafish: Speeding Up the Cancer Drug Discovery Process
Authors: Letrado Patricia , de Miguel Irene , Lamberto Iranzu , Díez-Martínez Roberto , Oyarzabal Julen
Published: April 2023

This file contains imaging techniques to monitor tumor process in zebrafish cancer models
Table S3 and S4 from Zebrafish: Speeding Up the Cancer Drug Discovery Process
Authors: Letrado Patricia , de Miguel Irene , Lamberto Iranzu , Díez-Martínez Roberto , Oyarzabal Julen
Published: April 2023

This file contains supplemental tables of zebrafish cancer models induced by chemical mutagenesis and by gene editing techniques
Tables S1-3 from Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Authors: Hompland Tord , Hole Knut Håkon , Ragnum Harald Bull , Aarnes Eva-Katrine , Vlatkovic Ljiljana , Lie A. Kathrine , Patzke Sebastian , Brennhovd Bjørn , Seierstad Therese , Lyng Heidi
Published: April 2023

Clinical characteristics, pimonidazole immunoscore and DWI parameters versus clinicopathological markers
Supplementary Method S2 from Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Authors: Hompland Tord , Hole Knut Håkon , Ragnum Harald Bull , Aarnes Eva-Katrine , Vlatkovic Ljiljana , Lie A. Kathrine , Patzke Sebastian , Brennhovd Bjørn , Seierstad Therese , Lyng Heidi
Published: April 2023

Construction of histology images of cell density and blood vessel density.
Table S5 from IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer
Authors: Wu Te-Chia , Xu Kangling , Martinek Jan , Young Robyn R. , Banchereau Romain , George Joshy , Turner Jacob , Kim Kyung In , Zurawski Sandra , Wang Xuan , Blankenship Derek , Brookes Hannah M. , Marches Florentina , Obermoser Gerlinde , Lavecchio Elizabeth , Levin Maren K. , Bae Sookyoung , Chung Cheng-Han , Smith Jennifer L. , Cepika Alma-Martina , Oxley Kyp L. , Snipes George J. , Banchereau Jacques , Pascual Virginia , O'Shaughnessy Joyce , Palucka A. Karolina
Published: April 2023

Clinical outcome in clinical trial
Table S3 from IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer
Authors: Wu Te-Chia , Xu Kangling , Martinek Jan , Young Robyn R. , Banchereau Romain , George Joshy , Turner Jacob , Kim Kyung In , Zurawski Sandra , Wang Xuan , Blankenship Derek , Brookes Hannah M. , Marches Florentina , Obermoser Gerlinde , Lavecchio Elizabeth , Levin Maren K. , Bae Sookyoung , Chung Cheng-Han , Smith Jennifer L. , Cepika Alma-Martina , Oxley Kyp L. , Snipes George J. , Banchereau Jacques , Pascual Virginia , O'Shaughnessy Joyce , Palucka A. Karolina
Published: April 2023

Information from patients in clinical trial
Table S2 from MYBL2 Supports DNA Double Strand Break Repair in Hematopoietic Stem Cells
Authors: Bayley Rachel , Blakemore Daniel , Cancian Laila , Dumon Stephanie , Volpe Giacomo , Ward Carl , Almaghrabi Ruba , Gujar Jidnyasa , Reeve Natasha , Raghavan Manoj , Higgs Martin R. , Stewart Grant S. , Petermann Eva , García Paloma
Published: April 2023

Gene expression analysis with Balance diagnosed composition
Supplementary figures from IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer
Authors: Wu Te-Chia , Xu Kangling , Martinek Jan , Young Robyn R. , Banchereau Romain , George Joshy , Turner Jacob , Kim Kyung In , Zurawski Sandra , Wang Xuan , Blankenship Derek , Brookes Hannah M. , Marches Florentina , Obermoser Gerlinde , Lavecchio Elizabeth , Levin Maren K. , Bae Sookyoung , Chung Cheng-Han , Smith Jennifer L. , Cepika Alma-Martina , Oxley Kyp L. , Snipes George J. , Banchereau Jacques , Pascual Virginia , O'Shaughnessy Joyce , Palucka A. Karolina
Published: April 2023

Figure S1. Cytokines screening from breast tumor tissue Figure S2. IL-1β induces TSLP production from breast cancer cells. Figure S3. IL-1β production in DCs is caspase-1 dependent. Figure S4. IL-1β production requires TAK1-dependent caspase-1 activation. Figure S5. IL-1 and TGF-β mediate tumor-promoting type 2 cytokines in humanized mouse model. Figure S6. Cells component in blood from patients in clinical trial. Anakinra signature clustered breast cancer patients in TCGA dataset.
Figure S1, Figure S2 and Table S1 from EGR1-Mediated Transcription of lncRNA-HNF1A-AS1 Promotes Cell-Cycle Progression in Gastric Cancer
Authors: Liu Hai-Ting , Liu Sen , Liu Lei , Ma Ran-Ran , Gao Peng
Published: April 2023

Figure S1 showed that the overexpression and knockdown efficiency of HNF1A-AS1 in both GC cells and the proliferation of GC cells transfected with SI-HNF1A-AS1-2 were inhibited. Figure S2 indicated that the migration, invasion and cell cycle progression of GC cells transfected with SI-HNF1A-AS1-2 were inhibited. Table S1 showed sequences of primers.
Figure S4 from Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation
Authors: van Lidth de Jeude Jooske F. , Spaan Claudia N. , Meijer Bartolomeus J. , Smit Wouter L. , Soeratram Tanya T.D. , Wielenga Mattheus C.B. , Westendorp B. Florien , Lee Amy S. , Meisner Sander , Vermeulen Jacqueline L.M. , Wildenberg Manon E. , van den Brink Gijs R. , Muncan Vanesa , Heijmans Jarom
Published: April 2023

Supplementary Figure S4
Supplementary Table S2 from p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Authors: Kajiwara Chihiro , Fumoto Katsumi , Kimura Hirokazu , Nojima Satoshi , Asano Keita , Odagiri Kazuki , Yamasaki Makoto , Hikita Hayato , Takehara Tetsuo , Doki Yuichiro , Morii Eiichi , Kikuchi Akira
Published: April 2023

Relationship between DKK3 and CKAP4 expression and clinicopathological characteristics of ESCC.
Supplementary Table 2 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

A) Cytosine Methylation Status by Mass Spectrometry.
Supplementary Figure 5 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

Uracil-DNA glycosylase (UDG) hydrolysis assay.
Supplementary Figure S3 from p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Authors: Kajiwara Chihiro , Fumoto Katsumi , Kimura Hirokazu , Nojima Satoshi , Asano Keita , Odagiri Kazuki , Yamasaki Makoto , Hikita Hayato , Takehara Tetsuo , Doki Yuichiro , Morii Eiichi , Kikuchi Akira
Published: April 2023

DKK3-CKAP4 signaling-dependent in vitro proliferation of KYSE960 cells used in the xenograft tumor formation assay. The binding of DKK3 to CKAP4 in vitro.
Supplementary Figure 4 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

AICDA and RELB expression after TKI exposure was inhibited upon pretreatment with BAY11-7802.
Supplementary Figure 1 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

Deamination of Cytosine or 5-methylcytosine to Uracil or Thymine respectively.
Fig, S6 from RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis
Authors: Zeng Fanxin , Chen Xiao , Cui Weiyi , Wen Wei , Lu Fujian , Sun Xueting , Ma Dongwei , Yuan Ye , Li Zezhong , Hou Ning , Zhao Hong , Bi Xinyu , Zhao Jianjun , Zhou Jianguo , Zhang Yan , Xiao Rui-Ping , Cai Jianqiang , Zhang Xiuqin
Published: April 2023

Figure S6. siRNA-mediated RIPK1 or MCU Silencing Inhibites the OCR. (A, B) Oxygen consumption rate of HT29 transfected with si-RIPK1 (200 pM) and si-MCU (200 pM, n=5). *p Ë, 0.05, **p Ë, 0.01, control vs treatment.
Table S1 from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State
Authors: Yoo Jae Hyuk , Brady Samuel W. , Acosta-Alvarez Lehi , Rogers Aaron , Peng Jingfu , Sorensen Lise K. , Wolff Roger K. , Mleynek Tara , Shin Donghan , Rich Coulson P. , Kircher David A. , Bild Andrea , Odelberg Shannon J. , Li Dean Y. , Holmen Sheri L. , Grossmann Allie H.
Published: April 2023

Table S1: ARF6 pathways and related genes.
Table S1 from APC/C-CDH1–Regulated IDH3β Coordinates with the Cell Cycle to Promote Cell Proliferation
Authors: Wu Qingnan , Zhang Weimin , Xue Liyan , Wang Yan , Fu Ming , Ma Liying , Song Yongmei , Zhan Qi-Min
Published: April 2023

Supplementary Table S1 Metabolic gene with KEN box and D box.
Supplementary Figure S6 from Proteolytic Release of the p75NTR Intracellular Domain by ADAM10 Promotes Metastasis and Resistance to Anoikis
Authors: Bao Xin , Shi Jianbo , Xie Furong , Liu Zengying , Yu Jingshuang , Chen Wantao , Zhang Zhiyuan , Xu Qin
Published: April 2023

Schematic representation of the role for ADAM10-p75NTR ICD-TRAF6-NF-kB axis in promoting anoikis resistance and metastasis identified in the present study.
Supplementary Figure S4 from Proteolytic Release of the p75NTR Intracellular Domain by ADAM10 Promotes Metastasis and Resistance to Anoikis
Authors: Bao Xin , Shi Jianbo , Xie Furong , Liu Zengying , Yu Jingshuang , Chen Wantao , Zhang Zhiyuan , Xu Qin
Published: April 2023

p75NTR ICD does not affect TRAF6 transcription, and TRAF6 wt, but not TRAF6 mut underwent ubiquitination under suspension culture condition.
Supplementary Movie S2 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer
Authors: Seo Jae Ho , Chae Young Chan , Kossenkov Andrew V. , Lee Yu Geon , Tang Hsin-Yao , Agarwal Ekta , Gabrilovich Dmitry I. , Languino Lucia R. , Speicher David W. , Shastrula Prashanth K. , Storaci Alessandra Maria , Ferrero Stefano , Gaudioso Gabriella , Caroli Manuela , Tosi Davide , Giroda Massimo , Vaira Valentina , Rebecca Vito W. , Herlyn Meenhard , Xiao Min , Fingerman Dylan , Martorella Alessandra , Skordalakes Emmanuel , Altieri Dario C.
Published: April 2023

Effect of scrambled MFF peptide on tumor cell morphology
SI Table S2 from Implications of Epigenetic Drift in Colorectal Neoplasia
Authors: Luebeck Georg E. , Hazelton William D. , Curtius Kit , Maden Sean K. , Yu Ming , Carter Kelly T. , Burke Wynn , Lampe Paul D. , Li Christopher I. , Ulrich Cornelia M. , Newcomb Polly A. , Westerhoff Maria , Kaz Andrew M. , Luo Yanxin , Inadomi John M. , Grady William M.
Published: April 2023

This file provides a list of the genomic location, associated genes, proximity to transcription start sites (TSS200 or TSS1500), the number of array probes and number of identified drift probes and the island-level drift rate (regression slopes) for each of the 781 identified drift-CGI in normal colon.
Supplementary Movie S1 from MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer
Authors: Seo Jae Ho , Chae Young Chan , Kossenkov Andrew V. , Lee Yu Geon , Tang Hsin-Yao , Agarwal Ekta , Gabrilovich Dmitry I. , Languino Lucia R. , Speicher David W. , Shastrula Prashanth K. , Storaci Alessandra Maria , Ferrero Stefano , Gaudioso Gabriella , Caroli Manuela , Tosi Davide , Giroda Massimo , Vaira Valentina , Rebecca Vito W. , Herlyn Meenhard , Xiao Min , Fingerman Dylan , Martorella Alessandra , Skordalakes Emmanuel , Altieri Dario C.
Published: April 2023

Morphology of MFF targeting in tumor cells
Supplementary Fig. 6 from In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis
Authors: Yogev Orli , Almeida Gilberto S. , Barker Karen T. , George Sally L. , Kwok Colin , Campbell James , Zarowiecki Magdalena , Kleftogiannis Dimitrios , Smith Laura M. , Hallsworth Albert , Berry Philip , Möcklinghoff Till , Webber Hannah T. , Danielson Laura S. , Buttery Bliss , Calton Elizabeth A. , da Costa Barbara M. , Poon Evon , Jamin Yann , Lise Stefano , Veal Gareth J. , Sebire Neil , Robinson Simon P. , Anderson John , Chesler Louis
Published: April 2023

Exogenous manipulation of STAT3 levels partially mimics the effect of CYT387, Th-MYCNCPM32 cell lines show cross resistance to front line chemotherapy.
Table S3 from Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy
Authors: Liu Changlong , Banister Carolyn E. , Buckhaults Phillip J.
Published: April 2023

Table S3. Negative selection scores of all genes from MAGeCK test
Supplementary Data - Figures S1_S2_S3_S4_S5 from Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy
Authors: Liu Changlong , Banister Carolyn E. , Buckhaults Phillip J.
Published: April 2023

Supplemental Figures S1, S2, S3, S4 and S5.
Figure S5 from The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right
Authors: Park Derek S. , Robertson-Tessi Mark , Luddy Kimberly A. , Maini Philip K. , Bonsall Michael B. , Gatenby Robert A. , Anderson Alexander R.A.
Published: April 2023

Expanded parameter analysis for model parameter omega. Increases in effector cell back-conversion rate lead to a larger Goldilocks Window.
Table S1 from DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy
Authors: Peiffer Daniel S. , Wyatt Debra , Zlobin Andrei , Piracha Ali , Ng Jeffrey , Dingwall Andrew K. , Albain Kathy S. , Osipo Clodia
Published: April 2023

PCR and ChIP Primer Sequences and KMplotter criteria
Figure S2 from ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma
Authors: Sachdeva Rohit , Wu Megan , Smiljanic Sandra , Kaskun Oleksandra , Ghannad-Zadeh Kimia , Celebre Angela , Isaev Keren , Morrissy A. Sorana , Guan Jennifer , Tong Jiefei , Chan Jeffrey , Wilson Taylor M. , Al-Omaishi Sayf , Munoz David G. , Dirks Peter B. , Moran Michael F. , Taylor Michael D. , Reimand Jüri , Das Sunit
Published: April 2023

(A) Western blot analysis for the identification of two clones lacking ID1 protein expression, consistent with successful gene knockout by CRISPR. (B) DNA sequence analysis of chosen clones. Red boxes mark the sgRNA target sequence and denote predicted cut-site. (C) Cell viability was measured using Alamar Blue in a time-dependent manner. (D) Cells were cultured for 48h followed by staining with propidium iodide for flow cytometric analysis. Bar chart shows quantification of the cell cycle distribution.
Supplementary Table S6 from Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3
Authors: Zheng Zi-Qi , Li Zhi-Xuan , Zhou Guan-Qun , Lin Li , Zhang Lu-Lu , Lv Jia-Wei , Huang Xiao-Dan , Liu Rui-Qi , Chen FoPing , He Xiao-Jun , Kou Jia , Zhang Jian , Wen Xin , Li Ying-Qin , Ma Jun , Liu Na , Sun Ying
Published: April 2023

Supplementary Table S6. The most differentially expressed lncRNAs between 3 pairs of NPC and normal nasopharynx tissues (fold change {greater than or equal to} 3, P-value < 0.05 and raw signal intensity > 1,500)
Tables S1-S3 from Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival
Authors: Moore Paul C. , Qi Jenny Y. , Thamsen Maike , Ghosh Rajarshi , Peng Justin , Gliedt Micah J. , Meza-Acevedo Rosa , Warren Rachel E. , Hiniker Annie , Kim Grace E. , Maly Dustin J. , Backes Bradley J. , Papa Feroz R. , Oakes Scott A.
Published: April 2023

CRISPR/Cas9 guide oligos, genotyping/sequencing primers, and q-PCR primers
Figure S5 from Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival
Authors: Moore Paul C. , Qi Jenny Y. , Thamsen Maike , Ghosh Rajarshi , Peng Justin , Gliedt Micah J. , Meza-Acevedo Rosa , Warren Rachel E. , Hiniker Annie , Kim Grace E. , Maly Dustin J. , Backes Bradley J. , Papa Feroz R. , Oakes Scott A.
Published: April 2023

KIRA8 and GSK-PKI induce distinct apoptotic markers in INS1 tumors