bluuebunny/crossref_metadata_2025 huggingface dataset:
Osmanlı Donanması için Canik ve Havalisinden Kereste Temini (1773-1840)
Authors: KOCAOĞLU Burak
Published: March 2022

Gemi inşasının tamamen ahşaba dayalı yürütüldüğü dönemlerde kereste temini ve nakli meselesi gemi inşa sürecindeki en önemli konuların başında gelmiştir. Bu noktada Kuzey Yarım Küre’de yaklaşık olarak 10-50° kuzey paraleli ve 0-60° doğu meridyeni arasında kalan Tropikal İklim ve Orta Kuşak olarak adlandırılan iki farklı iklim kuşağında hüküm sürmüş olan Osmanlı Devleti zengin bitki örtüsü ve orman alanıyla kereste temini noktasında çağdaşı olan çoğu devlete göre avantajlı bir konuma sahip olmuş ve bunu stratejik açıdan iyi değerlendirmiştir. Bu çalışmamız da devletin önemli kereste temin noktalarından birisi olan Canik ve havalisini ele almış bulunmaktayız. Çalışmamız da ilk olarak Osmanlı Devleti ve denizcilik faaliyetlerine çok kısa bir giriş yapıldıktan sonra Canik ve havalisinden kereste temini noktasında devletin nasıl bir yol izlediğini bu süreçte ne gibi sorunların yaşandığını ve devletin sorunlara ne gibi çözüm yolu bulduğunu arşiv kaynaklarına dayanarak gösterilmiştir.
On some qualitative properties of Ciric's fixed point theorem
Authors:   ", Moga Madalina ,   Babes-Bolyai University, Faculty of Mathematics and Computer Sciences, 1, Kogalniceanu Street, 400084 Cluj-Napoca, Romania e-mail: madalina.moga@math.ubbcluj.ro"
Published: March 2022

"It is well known that of all the extensions of the Banach-Caccioppoli Contraction Principle, the most general result was established by \'{C}iri\'{c} in 1974. In this paper, we will present some results related to \'{C}iri\'{c} type operator in complete metric spaces. Existence and uniqueness are re-called and several stability properties (data dependence and Ostrowski stability property) are proved. Using the retraction-displacement condition, we will establish the well-posedness and the Ulam-Hyers stability property of the fixed point equation $x=f(x)$."
Well-posedness for set-valued equilibrium problems
Authors:   ", Miholca Mihaela ,   Technical University of Cluj-Napoca, Department of Mathematics, 25, G. Baritiu Street, 400027 Cluj-Napoca, Romania e-mail: mihaela.miholca@yahoo.com"
Published: March 2022

"In this paper we extend a concept of well-posedness for vector equilibrium problems to the more general framework of set-valued equilibrium problems in topological vector spaces using an appropriate reformulation of the concept of minimality for sets. Su cient conditions for well-posedness are given in the generalized convex settings and we are able to single out classes of well-posed set-valued equilibrium problems. On the other hand, in order to relax some conditions, we introduce a concept of minimizing sequences for a set-valued problem, in the set criterion sense, and further we will have a concept of well-posedness for the set-valued equilibrium problem we are interested in. Suficient results are also given for this well-posedness concept."
Quasiconvex functions: how to separate, if you must!
Authors:   ", Frenk Johannes Bartholomeus Gerardus ,   Department of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey e-mail: frenk@sabanciuniv.edu", Gromicho Joaquim Antonio dos Santos ,   "University of Amsterdam, The Netherlands & ORTEC, Zoetermeer, The Netherlands e-mail: j.a.s.gromicho@uva.nl", Zhang Shuzhong ,   "Department of Industrial and Systems Engineering, University of Minnesota, Minneapolis, USA e-mail: zhangs@umn.edu"
Published: March 2022

"Since quasiconvex functions have convex lower level sets it is possible to minimize them by means of separating hyperplanes. An example of such a procedure, well-known for convex functions, is the subgradient method. However, to nd the normal vector of a separating hyperplane is in general not easy for the quasiconvex case. This paper attempts to gain some insight into the computational aspects of determining such a normal vector and the geometry of lower level sets of quasiconvex functions. In order to do so, the directional di erentiability of quasiconvex functions is thoroughly studied. As a consequence of that study, it is shown that an important subset of quasiconvex functions belongs to the class of quasidifferentiable functions. The main emphasis is, however, on computing actual separators. Some important examples are worked out for illustration."
Bounds for blow-up time in a semilinear parabolicproblem with variable exponents
Authors:   ", Rahmoune Abita ,   Department of Technical Sciences, Laboratory of Pure and Applied Mathematics, University of Laghouat 03000, Algeria e-mail: abitarahmoune@yahoo.fr", Benabderrahmane Benyattou ,   "Laboratory of Pure and Applied Mathematics, Mohamed Boudiaf University-M'Sila 28000, Algeria e-mail: bbenyattou@yahoo.com"
Published: March 2022

This report deals with a blow-up of the solutions to a class of semilinear parabolic equations with variable exponents nonlinearities. Under some appropriate assumptions on the given data, a more general lower bound for a blow-up time is obtained if the solutions blow up. This result extends the recent results given by Baghaei Khadijeh et al. \cite{Baghaei}, which ensures the lower bounds for the blow-up time of solutions with initial data $\varphi\left( 0\right) =\int_{\Omega }u_{0}{}^{k}dx$, $k$ = constant.
Root canal treatment of a maxillary second molar with four mesiobuccal root canals – a case report
Authors:   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal, Nogueira Flávia , Pires Mariana ,   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal, Baruwa Abayomi ,   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal, Pereira Beatriz ,   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal, Martins Jorge ,   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal,   Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal,   Centro de Estudo de Medicina Dentária Baseada na Evidência (CEMDBE) – Cochrane Portugal, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal, Ginjeira António ,   Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal,   Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal
Published: March 2022

Among the roots of maxillary molars, the mesiobuccal often presents with a root canal system that may be complex and variable, leading to a greater challenge when trying to achieve a proper chemo-mechanical preparation. The present report intends to show a successful root canal treatment of a maxillary second molar with six root canals, of which four were present in the mesiobuccal root. After being diagnosed with pulp necrosis and symptomatic apical periodontitis, a molar was endodontically treated. It also had an uncommon paracone cusp. A careful inspection of the pulp chamber floor revealed a mesiopalatal sulcus, which, after exploration with ultrasonic tips under an operating microscope magnification, showed three additional mesiobuccal root canals. After proper mechanical debridement, disinfection with sodium hypochlorite, and warm gutta-percha obturation, a favorable outcome was observed at the 12-month follow-up.
Land Records Modernisation in India: Haryana
Authors: Mitra Sudeshna , Goswami Amlanjyoti , Jha Deepika , Sasidharan Sahil , Lushington Kaye , Yadav Mukesh
Published: March 2022

This work provides an institutional, legal and policy review of crucial aspects of land records modernisation systems in Haryana. The state offers a unique window into the regional diversity of land systems in India; it underwent a large-scale land consolidation exercise in 1950s, and features rectangular land parcels of equal area, and a share-system of joint landholdings with limited spatial demarcation. Technologically, the state has an integrated system of land record management, and continues to make advances. Haryana is also one of the country’s most prolific real estate markets, attracting some of the largest private sector investment. However, the land records management system remains primarily rural, and does not yet capture the realities of an urban property landscape and the transition into a fragmented, individualised private property system.
Analysis of The Effect of Bank Capacitor Placement as Voltage Drop Increase in Distribution Network
Authors: Rofandy Muhammad Yudha , Hasibuan Arnawan , Rosdiana Rosdiana
Published: March 2022

The quality of electricity distribution in the distribution network is an important thing that must be considered. To maintain the quality of electrical energy, there are several parameters that must be considered in the distribution network, including voltage drop, power losses, power factor and other factors. One of the solutions used to improve the voltage drop and power factor is to install a capacitor bank in the distribution network. This paper will discuss the placement of capacitor banks using the fuzzy logic method with inputs in the form of voltage profiles, power losses and power flow calculations using ETAP 12.6.0 software. In the Rao feeder, the final voltage is 16.806 kV or has passed the standard set by PLN (-10% and +5%). The Rao feeder has a power loss of 0.242 MW and a power factor of 0.7815. Fuzzy logic method is used to determine the optimal location of capacitor placement. After the installation of the capacitor bank, the terminal voltage increases and the total power loss decreases, while the power factor increases. From the results obtained, PLN as a supplier of electrical energy can reduce power losses by placing and installing capacitor banks in the distribution network.
Pengaruh Persentase Nanoserat Pinang dan TiO2 Terhadap Sifat Listrik dan Sifat Mekanik Komposit Polianilin
Authors: 'Arifah Nur , Mahyudin Alimin
Published: March 2022

Penelitian mengenai pengaruh persentase TiO2Â dan nanoserat pinang terhadap sifat listrik dan sifat mekanik PANi. Penelitian ini bertujuan untuk menganalisis pengaruh penambahan TiO2Â terhadap PANi yang diperkuat nanoserat pinang. Perbandingan persentase TiO2Â dan nanoserat pinang yang ditambahkan pada PANi untuk uji sifat listrik berturut-turut adalah 27% : 3% ; 25% : 5% ; dan 23% : 7%. Perbandingan persentase TiO2Â dan nanoserat pinang yang ditambahkan pada PANi untuk uji sifat mekanik berturut-turut adalah 3% : 2% ; 2% : 3% ; dan 1% : 4%. PANi dipolimerisasi dari monomer anilin menggunakan metode polimerisasi oksidasi kimia. Metode pembuatan nanoserat pinang menggunakan metode dewaxing, bleachingÂ dan dehemiselulosa. Pembuatan komposit dilakukan melalui metode dry mixing (pencampuran kering) antara nanoserat pinang dan PANi-TiO2. Pengujian yang dilakukan berupa uji sifat listrik (konduktivitas dan kapasitansi), uji sifat mekanik (kuat tarik, regangan dan modulus elastisitas), SEM dan XRD.Â Hasil karakterisasi menggunakan XRD diperoleh puncak untuk nanoserat pinang dan TiO2. Hasil pengamatan SEM pada permukaan filmÂ PANi-TiO2 nanoserat pinang ukuran partikel berbeda-beda. Berdasarkan hasil pengujian yang telah dilakukan, nilai konduktivitas semakin tinggi seiring penambahan nanoserat pinang dengan nilai sebesar 3,25 x 10-3Â S/cm. Penambahan nanoserat pinang pada persentase 4% menghasilkan nilai kuat tarik, regangan dan modulus elastisitas berturut-turut 1,6 MPa, 16,67% dan 9,4 MPa
Estudo transversal da avaliação das causas gestacionais e maternas associadas à prevalência de nascidos vivos com gastrosquise
Authors: Lima Kauanny Fernandes , Magalhães Bruna Garcia Vilar de , Gomes Felipe Kliemaschewsk Ferreira , Almeida Francisco Jammal Simão de , Júnior Justo Reynaldo Padilla Bustamante , Medeiros Karoline Lopes Lellis  de , Oliveira Gisele do Couto
Published: March 2022

Objetivo: Compreender os aspectos epidemiológicos e sociodemográficos associados à ocorrência de gastrosquise em recém-nascidos vivos de gestantes com atendimento pré-natal no Estado de Mato Grosso (MT). Métodos: Trata-se de um estudo transversal em que as informações foram quantificadas através da Declarações de Nascimentos Vivos realizadas entre 01/01/2015 a 31/12/2015, sendo as variáveis separadas para análise no Epi info™ para associação entre exposição, fatores de risco e desfecho gerando significância estatística. Resultados: Na amostra total de 43 223 mulheres, através da análise bivariada foi constatada maior prevalência de gastrosquise em filhos de primíparas (IC95% 1,88; 4,78), na faixa etária de risco ≤18 ou ≥36 (IC95% 1,31; 3,63), solteiras, separadas ou viúvas (IC95% 1,84;4,65) e que realizaram até 6 consultas pré-natais (IC95% 0,81; 2,04). Em relação ao neonato, houve maior prevalência da anomalia em fetos prematuros (IC95% 4,30;10,60). Em relação a disposição geográfica, destacaram-se as cidades de Sinop, Rondonópolis, Diamantino e Juara, todas pertencentes a áreas de exposição à agrotóxicos (IC95% 2,08;5,12) e regiões com alto IDH (IC95% 2,17;10,30). Conclusão: Primiparidade, regiões com alto IDH, áreas de exposição à agrotóxicos, mães sem união estável, prematuridade e baixa idade materna são fatores de risco para ocorrência da gastrosquise.
Efeitos da pandemia da Covid-19 na condução da farmacoterapia em idosos com hipertensão e diabetes atendidos em uma Policlínica no Estado de Pernambuco
Authors: Silva Nyllaha Rosângela Costa da , Ferreira Maria Eduarda Paiva do Rêgo Quintas , Gomes Elisangela Christhianne Barbosa da Silva , Pontes Margareth Rose de Lyra , Melo Silvia Pereira da Silva de Carvalho , Santos Mônica Maria Henrique dos , Melo Janaína Gonçalves da Silva , Barreto Maria Nelly Sobreira de Carvalho
Published: March 2022

Objetivo: Descrever os impactos da Covid-19 na condução da farmacoterapia em idosos com hipertensão e diabetes, atendidos em uma policlínica localizada no estado de Pernambuco, considerando as características dos usuários e do seu tratamento farmacológico. Métodos: Trata-se de um estudo descritivo com abordagem quantitativa realizado em duas etapas. Na primeira etapa, foi realizada uma análise retrospectiva do banco de dados do Sistema Hórus, para levantamento dos hipertensos e/ou diabéticos, acima de 60 anos, cadastrados neste sistema, levando em consideração os perfis de anti-hipertensivos e antidiabéticos. Na segunda etapa, foram realizadas entrevistas com os idosos pré-selecionados, por meio de amostra por conveniência, segundo dados do relatório da primeira etapa. Resultados: Dos 42 idosos entrevistados, a maioria era mulher (69,05%) e a faixa etária predominante entre 70 a 79 anos (45,24%). Apenas 2,4% afirmaram suspensão do tratamento farmacológico e a maioria continuou recebendo medicamentos na policlínica. Os entrevistados relataram terem recebido orientações dos profissionais de saúde, principalmente médicos e farmacêuticos. Os idosos referiram cuidados para prevenção da Covid-19 e menos de 20% foram contaminados. Conclusão: Evidenciou-se a importância da adesão ao tratamento farmacológico, bem como o apoio dos profissionais de saúde, para minimizar os problemas causados pela Covid-19 em idosos.
Ações de saúde desenvolvidas em escolas de educação infantil sob a perspectiva dos professores
Authors: Lisboa Daniela Gomes de Freitas , Piccolo Josiane , Rezende Helena de
Published: March 2022

Objetivo: Mapear as ações de saúde desenvolvidas nas Escolas de Educação Infantil (EEI) e identificar o papel do enfermeiro sob a perspectiva dos professores. Métodos: Estudo quantitativo do tipo observacional e descritivo, com aplicação de questionário online para professores de educação infantil que atuam em um município do estado de São Paulo, seguindo o método bola de neve. Resultados: A amostra foi constituída por 39 participantes, onde 92,3% eram do gênero feminino e 82,1% não possuíam treinamento em saúde. As ações de saúde mais frequentes foram a promoção da alimentação saudável (84,6%) e o monitoramento do estado vacinal (82,1%); ações de prevenções tais como de acidentes e de doenças transmissíveis foram poucas desenvolvidas e corresponderam 35,9% e 33,3% respectivamente. Somente 5,1% professores relataram a presença do enfermeiro no quadro de profissionais de saúde das EEI, porém 94,5% expressaram a importância deste profissional nas escolas Conclusão: A análise dos dados evidenciou que são diversas ações de saúde desenvolvidas nas EEI, no entanto, não estão totalmente implementadas, revelando que os profissionais de saúde precisam atuar no ambiente escolar. Do ponto de vista dos professores, a presença do enfermeiro na EEI desempenha um papel fundamental.
Pictorial review of computed tomography features of diffuse cystic lung disease
Authors: Chan Yi Lam Priscilla , Yu Chun Hung Kevin , Chong Wing Ho , Kwok Kai Yan , Li Allen
Published: March 2022

Diffuse cystic lung disease represents a diverse group of uncommon disorders that has been increasingly diagnosed due to the increasing use of computed tomography. It poses a frequent diagnostic challenge to radiologists due to the similar clinical and radiological features these diseases share. This pictorial review includes selected cases from the Hospital Authority New Territories West Cluster (NTWC) in Hong Kong from the past 3 years. It will illustrate the spectrum of diffuse cystic lung diseases, including some rarer entities in our locality, and identify the pertinent differentiating imaging features on CT. A flowchart to summarize these features is provided at the end to aid in diagnosis.
Psychological Well-Being in Postoperative Pain: A Correlational Study
Authors: MAKAL ORĞAN Esra , YILDIZELİ TOPÇU Sacide
Published: March 2022

Background: This study aims to determine the role of postoperative pain experienced by patients in their psychological well-being.
Materials and Methods: This correlational study was conducted with 63 volunteer patients who underwent surgery.
Results: There was a negative correlation between psychological well-being and postoperative pain level, and also, age of the patients.
Conclusion and suggestions: The increased pain severity caused decreasing psychological well-being. Decreased psychological well-being may affect the healing process negatively by impairing the participation of patients in their own treatment and care. Nurses can help patients maintain their psychological well-being through good pre-operative psychological preparation and effective postoperative pain control.
Computing Optimal Repairs of Quantified ABoxes w.r.t. Static EL TBoxes (Extended Version)
Authors: Baader Franz , Koopmann Patrick , Kriegel Francesco , Nuradiansyah Adrian
Published: March 2022

The application of automated reasoning approaches to Description Logic (DL) ontologies may produce certain consequences that either are deemed to be wrong or should be hidden for privacy reasons. The question is then how to repair the ontology such that the unwanted consequences can no longer be deduced. An optimal repair is one where the least amount of other consequences is removed. Most of the previous approaches to ontology repair are of a syntactic nature in that they remove or weaken the axioms explicitly present in the ontology, and thus cannot achieve semantic optimality. In previous work, we have addressed the problem of computing optimal repairs of (quantified) ABoxes, where the unwanted consequences are described by concept assertions of the lightweight DL EL. In the present paper, we improve on the results achieved so far in two ways. First, we allow for the presence of terminological knowledge in the form of an EL TBox. This TBox is assumed to be static in the sense that it cannot be changed in the repair process. Second, the construction of optimal repairs described in our previous work is best case exponential. We introduce an optimized construction that is exponential only in the worst case. First experimental results indicate that this reduces the size of the computed optimal repairs considerably.
FISHING LINKS OF THE SEA-ECONOMIC COMPLEX OF THE RUSSIAN FAR EAST
Authors: Мошков А.В.
Published: March 2022

Морехозяйственный комплекс Дальнего Востока выполняет важную роль в экономике страны, обеспечивая основную долю в уловах рыбы и морепродуктов, производстве пищевой рыбопродукции. Важнейшей составляющей морехозяйственного комплекса Дальневосточного региона России выступает рыбопромышленная деятельность. Выделяются благоприятные факторы развития вида экономической деятельности в регионе, а также основные проблемы (в первую очередь производство и экс порт преимущественно сырья и полуфабрикатов, т.е. продукции с низкой добавленной стоимостью). Кроме этого, в регионе слабо развита база судостроения и судоремонта рыбодобывающего флота, практически отсутствуют современные рынки сбыта продукции рыбного промысла. Изучение процессов формирования территориальной и функциональной структуры морехозяйственных комплексов акватерриториальных производственных систем является актуальной теоретической проблемой современной экономической географии, решение которой имеет также большое практической значение для целей территориального управления.

The sea economic complex of the Far East plays an important role in the economy of the country, providing the main share in the catches of fi sh and seafood, and in production of food fi sh products. The fi shing activity is the most important component of the marine industry of the Far Eastern region of Russia. The favorable factors of development of the type of economic activity in the region, and also the main problems (fi rst of all, production and export mainly of raw materials and semifi nished products, i.e. production with low added value) are allocated. In addition, the region has a poorly developed base of shipbuilding and ship repair of the fi shing fl eet practically there are no modern markets for fi shery products. The studies of the processes of formation of the territorial and functional structure of marine complexes an aquaterritorial production systems is an actual theoretical problem of modern economic geography, the solution of which is also of great practical importance for the purposes of territorial administration.
FEATURES OF ORTHOSTATIC HYPOTENSION IN PATIENTS WITH HIGH BLOOD PRESSURE
Authors: Вылегжанина Е.В. , Валиуллин Н.Р. , Загидулина С.И. , Лисицына Д.Ю. , Сайфуллина А.Р. , Саляхиева А.А. , Одинцова Н.Ф.
Published: March 2022

По статистике, 30 населения земного шара отмечают у себя повышенный уровень артериального давления (АД). Из них, около 50 составляет доля населения в возрасте старше 50 лет. По данным Всемирной Организации Здравоохранения, артериальная гипертензия (АГ), на сегодняшний день, занимает 1 место в Российской Федерации в структуре причин инвалидизации и смертности населения, в том числе трудоспособного возраста 3. Особую сложность в подборе антигипертензивной терапии составляет сочетание АГ и ортостатической гипотензии (ОГ). ОГ значительно ухудшает качество жизни у этих пациентов и является фактором риска неблагоприятного прогноза 1, 2. ОГ характеризуется снижением систолического (С) АД на 20 мм рт.ст. и/или диастолического (Д) АД на 10 мм рт. ст. в течение 3 минут после перехода в вертикальное положение (ортостаз). Распространенность ОГ колеблется от 7 у здоровых пожилых людей без АГ до 30 у лиц старше 75 лет с различными коморбидными состояниями.

According to statistics, 30 of the worlds population report an elevated level of blood pressure. Of these, about 50 is the proportion of the population over the age of 50 years. According to the World Health Organization, arterial hypertension currently occupies the fi rst place in the Russian Federation in the structure of causes of disability and mortality of the population, including the working age 3. AH in the elderly has its own laws. One of the features is the combination of hypertension and hypertension, which degrades the quality of life of patients and is a risk factor for poor prognosis. Orthostatic hypotension is characterized by a decrease in CBP in 20 mm Hg. and / or DBP at 10 mm Hg. within 3 minutes after the transition to a vertical position (orthostasis). The prevalence of exhaust gas is quite high and ranges from 7 in healthy elderly people without hypertension to 30 in people over 75 years of age with various comorbid conditions. The combination of AH and EG is a particular diffi culty for the doctor, since the treatment of one condition certainly worsens the course of another 1, 2.
CORRECTION OF IODINE DEFICIENCY IN YOUNG MINK (NEOVISON VISON) SCANDINAVIAN SELECTION DURING THE SUMMER AND AUTUMN HAIRLINE CHANGE
Authors: Лоенко Н.Н. , Кровина Е.В. , Демина Т.М. , Растимешина О.В. , Майоров А.И. , Тинаева Е.А.
Published: March 2022

Установлено, что введение органического йода в рацион молодняка норок в период летней и осенней смены волосяного покрова позволяет корректировать йододефицитное состояние и процесс созревания зимнего волосяного покрова у молодняка норок.

It was established that the introduction of organic iodine into the diet of young minks during the summer and autumn hairline change makes it possible to correct the iodine defi ciency state and the maturation process of winter pubescence of young minks.
ADAPTIVE INTERPOLATION METODS
Authors: Нейман Ю.М. , Сугаипова Л.С.
Published: March 2022

Рассмотрены методы адаптивной интерполяции скалярного поля, опирающиеся на использование свёртки. Ядро свёртки адаптируется под локальные особенности рассматриваемого сигнала с учётом расстояния до ближайшей точки с измерениями. Использование так называемых карт достоверности позволяет делать чёткое различие между точками, где измерения равны нулю и где они отсутствуют. В статье приводится возможный алгоритм выполнения адаптивной интерполяции в окрестности каждой точки выборки.

Methods of adaptive interpolation of scalar fi eld are considered. They are based on use of a convolution. The convolution kernel adapts to the local features of the signal under consideration taking into account the distance to the nearest point with measurements. The use of so-called certainty maps allows a clear distinction to be made between points where the measurements are zero and where they are absent. The paper provides a possible algorithm for performing adaptive interpolation in the vicinity of each sampling point.
Spontaneous and Ion-Specific Formation of Inverted Bilayers at Air/Aqueous Interface
Authors: Nayak Srikanth , Kumal Raju R , Uysal Ahmet
Published: March 2022

Developing better separation technologies for rare earth metals, an important aspect of a sustainable materials economy, is challenging due to their chemical similarities. Identifying molecular scale interactions that amplify the subtle differences between the rare earths can be useful in developing new separation technologies. Here, we describe ion-dependent monolayer to inverted bilayer transformation of extractant molecules at the air/aqueous interface. The inverted bilayers form with Lu3+ ions but not with Nd3+. By introducing Lu3+ ions to preformed monolayers, we extract kinetic parameters corresponding to the monolayer to inverted bilayer conversion. Temperature-dependent studies show Arrhenius behavior with an energy barrier of 40 kcal/mol. The kinetics of monolayer to inverted bilayer conversion is also affected by the character of the background anion, although anions are expected to be repelled from the interface. Our results show the outsized importance of ion-specific effects on interfacial structure and kinetics, pointing to their role in chemical separation methods.
1’-cyano substitution of Remdesivir “template-dependent” inhibiting the transcription of SARS-CoV-2
Authors: Luo Xueying , Wang Xiaowei , Gao Xin , Zhang Lu
Published: March 2022

Remdesivir is one nucleotide analog prodrug capable to terminate RNA synthesis in SARS-CoV-2 RdRp by two distinct mechanisms. The “delayed chain termination mechanism” has been extensively investigated, while the “template-dependent inhibition mechanism” remains elusive. In this study, we have demonstrated that Remdesivir embedded in the template strand seldom directly disrupted the complementary NTP incorporation at the active site. Instead, the translocation of the template strand from +2 to +1 site was hindered, as the 1’-cyano group of Remdesivir would sterically clash with V557. Moreover, we have elucidated the molecular mechanism of how SARS-CoV-2 RdRp gained the drug resistance to Remdesivir upon V557L mutation. Overall, our studies provided valuable insight into the “template-dependent inhibition mechanism” exerted by Remdesivir on SARS-CoV-2 RdRp and paved venues for an alternative drug design strategy for the treatment of COVID-19.
Structure and Stability of 7-mercapto-4-methylcoumarin SAM on Gold: an Experimental and Computational analysis.
Authors: Marchi Davide , Cara Eleonora , Ferrarese Lupi Federico , Hönicke Philipp , Kayser Yves , Beckhoff Burkhard , Castellino Micaela , Zoccante Alberto , Laus Michele , Cossi Maurizio
Published: March 2022

Self-assembled monolayers of 7-mercapto 4-methylcoumarin (MMC) on a flat gold surface were studied by Molecular Dynamics (MD) simulations, reference-free grazing incidence X-ray fluorescence (GIXRF) and X-ray photoemission spectroscopy (XPS), to determine the maximum monolayer density and to investigate the nature of the molecule/surface interface. In particular, the protonation state of the sulfur atom upon adsorption was analyzed, since some recent literature presented evidences for physisorbed thiols (preserving the S-H bond), unlike the common picture of chemisorbed thiyls (losing the hydrogen). MD with a specifically tailored force field was used to simulate either thiol or thiyl monolayers with increasing number of molecules, to determine the maximum dynamically stable densities. This result was refined by computing the monolayer chemical potential as a function of the density with the Bennet Acceptance Ratio method, based again on MD simulations. The monolayer density was measured with GIXRF, which provided a quantitative estimate of the number of sulfur atoms on top of flat gold surfaces embedded in a solution of MMC, to allow the formation of a dense monolayer. The sulfur core level binding energies in the same monolayers were measured by XPS, fitting the recorded spectra with the binding energies proposed in the literature for free or adsorbed thiols and thiyls, to get insight on the nature of the molecular species present in the layer.
Novel Azo-Stilbene and Pyridine-Amine Hybrid Multifunctional Molecules to Target Metal Mediated Neurotoxicity and Amyloid-β Aggregation in Alzheimer’s disease
Authors: Rana Monika , Cho Hong-Jun , Arya Hemant , Bhatt Tarun , Bhar Kishalay , Bhatt Surabhi , Mirica Liviu , Sharma Anuj
Published: March 2022

Neurodegenerative diseases such as Alzheimer’s diseases (AD) are associated with progressive neuronal cell death and a common correlation is aberrant protein misfolding and aggregation of the Aβ peptide. Transition metal ions (Cu, Fe and Zn) have been shown to promote aggregation and oxidative stress through formation of Aβ-metal complexes. In this context, integrating molecular scaffolds rationally is used here to generate multifunctional molecules as modulators for metal-induced abnormalities. This work encompasses two novel compounds (HL1 and HL2), the rationale behind the design, their synthesis, characterization and metal chelation ability [Cu(II) and Zn(II)]. The molecular frameworks of the designed compounds consist of stilbene as an Aβ interacting moiety; whereas N,N,O and N,N,N,O donor atoms are linked to generate the metal chelation moiety. Further, we went on exploring their multifunctionality w.r.t. to (i) their metal chelating capacities (ii) their utility to modulate the aggregation pathways of both metal-free and metal-bound amyloid-β, (iii) scavenge free radicals, (iv) inhibit the activity of acetylcholinesterase and (v) cytotoxicity. Moreover, the compounds were able to sequester Cu2+ from the Aβ-Cu complex and thus disrupt the redox cycle. Molecular docking studies were also performed with Aβ and acetylcholinesterase enzyme. Overall, the studies presented here qualify these molecules as promising anti-Alzheimer’s candidates.
State-specific solvation for restricted active space spin-flip (RAS-SF) wave functions based on the polarizable continuum formalism
Authors: Alam Bushra , Jiang Hanjie , Zimmerman Paul , Herbert John
Published: March 2022

The restricted active space spin-flip (RAS-SF) formalism is a particular form of single-reference configuration interaction that can describe some forms of strong correlation at relatively low cost, and which has recently been formulated for the description of charge-transfer excited states. Here, we introduce both equilibrium and nonequilibrium versions of a state-specific solvation correction for vertical transition energies computed using RAS-SF wave functions, based on the framework of a polarizable continuum model (PCM). Ground-state polarization is described using the solvent's static dielectric constant and in the nonequilibrium solvation approach that polarization is modified upon vertical excitation using the solvent's optical dielectric constant. Benchmark calculations are reported for well-studied models of photo-induced charge transfer including naphthalene dimer, C2H4...C2F4, pentacene dimer, and perylene diimide (PDI) dimer, several of which are important in organic photovoltaic applications. For the PDI dimer, we demonstrate that the charge-transfer character of the excited states is enhanced in the presence of a low-dielectric medium (static dielectric constant epsilon = 3) as compared to a gas-phase calculation (epsilon = 1). This stabilizes mechanistic traps for singlet fission and helps to explain experimental singlet fission rates. We also examine the effects of nonequilibrium solvation on charge-separated states in an intramolecular singlet fission chromophore, where we demonstrate that the energetic ordering of the states changes as a function of solvent polarity. The RAS-SF + PCM methodology that is reported here provides a framework to study charge-separated states in solution and in photovoltaic materials.
Preparation and Characterization of Natural Face Pack
Authors: Prakash Gnana
Published: March 2022

Herbal Products have huge demand from few decades as they yield good results without any side effects and provide a soothing effect for longer period of time. Using natural ingredients in a cosmetic formulation thus provides healthy and glowing skin. Currently, due to increase in pollution rate, skin allergic conditions, microbes and external effects human skin have become sensitive and prone to faster aging. Here we have made an attempt to formulate a pack ideal for all skin types. Thus, in the current work, the face packs that can be easily made with the available ingredients showed all the benefits and further optimization studies are necessary on various parameters to identify benefits on humans. The flow properties of natural herbal face pack show accurate results. All the ingredients were mixed homogenously and were evaluated for parameters like organoleptic properties (Appearance, color, odor, texture & smoothness) particle size ranges from 23.5±2.15 ?m to 24.4±5.14 ?m, Ash content ranges from 86 ± 0.951 % to 94 ± 0.34 %, pH was ranges from 6.51 ± 0.12 to 6.65± 0.16. Loss on drying ranges from 3.18 % to 4.12 %. Irritancy tests, rheological features and stability. The obtained results showed that the prepared formulation was stable on all parameters. Irritancy test revealed negative. Stability tests showed the inertness of the formulation.
Numerical Experiments of the Dual Null Field Method for Dirichlet Problems of Laplace’s Equation in Elliptic Domains with Elliptic Holes
Authors:   National Sun Yat-sen University, Li Zi-Cai , Huang Hung-Tsai ,   I-Shou University, Zhang Li-Ping ,   Zhejiang University of Technology, Lempert Anna ,   Matrosov Institute for System Dynamics and Control Theory SB RAS, Lee Ming-Gong ,   Chung Hua University
Published: March 2022

Dual techniques have been used in many engineering papers to deal with singularity and ill-conditioning of the boundary element method (BEM). In the first part of the two-part article, our efforts were focused on studying the theoretical aspects of this problem, including the analysis of errors and the study of stability. We provided the theoretical analysis for Laplace equation in elliptic domains with elliptic holes. To bypass the degenerate scales of Dirichlet problems, the second and the first kinds of the null field methods (NFM) are used for the exterior and the interior boundaries, simultaneously. This approach is called the dual null field method (DNFM). This paper is the second part of the study. Numerical results for degenerate models of an elliptic domain with one elliptic hole at 𝑎 + 𝑏 = 2 are carried out to verify the theoretical analysis obtained. The collocation Trefftz method (CTM) is also designed for comparisons. Both the DNFM and the CTM can provide excellent numerical performances. The convergence rates are the same but the stability of CTM is excellent and can achieve the constant condition numbers, Cond = 𝑂(1).
Approximating generalized laplace transforms
Authors: Diego Caratelli  , Paolo Emilio Ricci
Published: March 2022

An extension of the Laplace transform (LT) obtained by using Bell polynomials and Laguerre-type exponentials was recently introduced. Computational techniques for evaluating the transformed functions numerically are developed. To this end, Tricomi’s method is applied in combination with the matrix pencil method for approximating the kernel of generalized Laplace transforms
APPLYING VLOG IN TEACHING VOCABULARY
Authors: Syam Nur Ina , Emirati Emirati
Published: March 2022

The aim of this study is to find out whether or not the use of vlog will enhance the vocabulary of the students. This study used pre-experimental studies consisting of pre-test, treatment, and post-test. The participants in the study were 25 students of the second grade students of Universitas Muhammadiyah Bulukumba. Based on the findings of the study, there is a substantial difference between the mean pre-test score and the mean post-test score, from a very bad classification to a decent classification. In addition, the t-test value of this analysis (16,12) is greater than the t-table value (3,745) with a degree of significance of 0,05. It means that it supports the alternative hypothesis.
ANALYSIS OF VAK STUDENT LEARNING STYLE PGSD UKI TORAJA
Authors: Patintingan Mersilina Luther , Lolotandung Reni
Published: March 2022

One of the factors that affect a person's learning outcomes is their learning style(Aryo Andri Nugroho, Ida Dwijayanti 2017). The division of student classes, taking into account each individual's learning styles; will greatly aid instructors in preparing teaching methods and materials that are appropriate for the students' learning styles. The VAK (Visual, Auditory and Kinesthetic) learning style was developed by Rita Dunn and Kennenth Dunn(Lehmann dan Ifenthaler 2012). Children with visual learning styles typically learn through external visual relationships, children with auditory learning styles learn more easily through listening, and children with kinesthetic learning styles learn through physical movements to input information into their brain(Sari n.d.).The aim of this study is to describe the results of the VAK analysis of the learning style (visual, auditory and kinesthetic) of students in the UKI Toraja PGSD study program in order to address issues related to the National Research Master Plan (RIRN) on Social Humanities, Cultural Arts, and education bureau can solve. Domestic studies on educational and learning technology. This research will be carried out in 3 (three) stages. The first phase was to observe the VAK (Visual, Auditory and Kinesthetic) learning style of the UKI Toraja PGSD study program students. In the second phase, data was collected and direct interviews were conducted with relevant sources on the VAK (Visual, Auditory and Kinesthetic) learning style of students in the UKI Toraja PGSD study program. The third phase is to manage and analyze the results of face-to- face interviews and to publish the results of research on the VAK learning styles (visual, auditory and kinesthetic) of students in the UKI Toraja PGSD study program. The results of the analysis of the VAK learning style of students in the UKI Toraja PGSD study program for the 2019/2020 academic year. This research is a descriptive study with a qualitative approach. The subjects of this study were all students in the 2018/2019 primary school teacher-training course. The instrument used in this study was a questionnaire, the content of which was adapted from 18 elements from the versions of Rita and Kenneth Dunn. These are then grouped into 6 subsections of learning styles that are common to students, namely: Visual, Auditory, and Kinesthetic. The data analysis used in this study is a descriptive analysis using statistical methods. Based on the results of the analysis of the study style questionnaire of 2018 UKI Toraja PGSD students, of which the respondents were 282 students, the auditory was 34.2%, the visual 44.7% and the kinesthetic 21.1%. From the above data, it can be concluded that the class of PGSD students in 2018 has a predominantly visual learning style.
THE EFFECT OF PICTURE WORD INDUCTIVE MODEL (PWIM) ON THE STUDENTS’ ENGLISH WRITING ACHIEVEMENT AT JUNIOR HIGH SCHOOL
Authors: Aris Patmawati , Ampa Andi Tenri , Sulfasyah Sulfasyah
Published: March 2022

This research was aimed to know the effect of using Picture Word Inductive Model (PWIM) on the students’ achievement of writing skills.This research implemented the design of quasi-experimental which consisited of two classes of the same level. This research applied total sampling technique, because therewere just two classes of the seventh grade, namely: VII A as the sample of experimental group and VII B as the control group. The total numbers of the sample was 25 students for each group. the data were analyzed quantitatively. The results of statistical analysis showed that the mean score of students' posts in the experimental group was 88.20 which was categorized as “Very Good” while the average post-score of students in the control group was 81.20 which was categorized as “Good”. This shows that after being given treatment, the average value of the experimental group is higher in the control group. It proves that the treatment by applying PWIM can give effect to improve the students’ writing achievement. It was also indicated that t-value (2.78) t-table (1.68), with df. 48, Sig. (2 tailed) and the level of significance was 0.05 which was smaller than t-value (0.008 0.05).This means that there was a significant difference of students’ writing achievement between experimental class and control class after being treated by using PWIM
STUDENTS’ VOCABULARY MASTERY BEFORE AND AFTER TAUGHT USING TALKING STICK STRATEGY
Authors: Jusman Jusman , Latifa Ammang , Amaluddin Amaluddin
Published: March 2022

This exploration was expected to uncover that: to discover the understudies' vocabulary dominance previously, after educate through talking stick strategy, additionally the huge distinctive the understudies' vocabulary authority at the long term understudies of SMP Negeri 5 Pinrang. This examination utilized semi test strategy, with two gathering pre-test and post-test plan. The general population was the drawn out understudies of SMP Negeri 5 Pinrang. The example is picking by random sampling technic. Where, the specialist accept one class as trial class and one class as control class. The outcome of the data assessment showed that the understudies' jargon predominance improved through and through when given treatment. It was showed up by the mean score of the pre-test was (67.96) and the post-test was (78.70). It showed that talking stick strategy can improve the jargon authority of the drawn out understudies of SMP Negeri 5 Pinrang out and out. Resulting to inspecting the data by using t-test formula, the eventual outcome of t-test regard (4.58) and t-table (2.021), Those showed that H1 was recognized and H0 was excused.
ENGLISH VIRTUAL BASED LEARNING: INTEGRATING TECHNOLOGY AND LEARNING MEDIA THROUGH ‘ASSURE’ TEACHING MODEL
Authors: Arriyani Nurfisi , Pratama Putra
Published: March 2022

This research had the objective to measure the effectiveness of ASSURE teaching model in the integration of technology and learning media in the process of virtual-based English learning. One class comprising of 20 students of 6th grade was chosen as the sample of this study. A quantitative descriptive method was applied by using both pre-and post-tests as the instruments in collecting the data. In analyzing the data, the average score difference gained by the students in these two tests was firstly measured before they were further calculated through the 'Paired sample t-test'. The analysis revealed that the mean score reached by the students in the post-test (80.75) was higher than their performance in the pre-test (56). Additionally, the t-test score hit by these students was 14.14; bigger than the value of the t-table (1.73) in the significance level of 5% (0.05). This also explained that ASSURE teaching model as variable X significantly influenced students' English achievement (variable Y).  These findings confirmed that in the integration of technology and learning media in English virtual instruction, ASSURE teaching model was effective in increasing students' English achievements.
Bilingual Approach: The Role of Flashcards in Teaching Vocabulary to Young Learners
Authors: Erniwati Erniwati , Mertosono Sudarkam R , Arid Muhammad , Anggreni Afrillia
Published: March 2022

This paper discusses teaching approach and media in English as a foreign language (EFL) classroom. It brings to lights vocabulary teaching, bilingual approach and using flashcards in the teaching of vocabulary to young learners. As teaching vocabulary can take place from very early stage to a high level of learning, its introduction needs to be managed in such a way using an appropriate approach along with utilizing particular media, such as flashcards, that the learners can enjoy the teaching process. This is based on the consideration that not all teaching media fit in the context of vocabulary teaching through bilingual approach. For this reason, it is important that teachers of English whose concern is how young learners learn vocabulary adopt appropriate teaching media on their behalf. Once the learners feel secured and confortable with the media used, it is guaranteed that they can learn as many words as possible and, thus, the desired outcome of the learning can be projected to occur. This article emphasizes the issue of bringing together bilingual approach and flahcards together in the teaching of vocabulary to young learners.
IDENTIFICATION OF BUGINESE STUDENTS’ LEARNING NEEDS FOR A PRIVATE ENGLISH CRASH COURSE
Authors: Nur Rafi'ah
Published: March 2022

This study aims to identify the needs of Buginese learners in mastering English in the crash course program at Neroa School, a non-formal English course institution in Soppeng Regency, South Sulawesi, Indonesia. This research method was a descriptive research. The instrument used by the researcher to collect data was a questionnaire that was previously validated by an expert. In processing data of the questionnaire, the researcher implemented an approach including stages of presentation of descriptive statistics. This approach refers to Gay (2012), Johnson Christensen (2014), and each analysis phase adopts Nur (2015). There were five basic components represented in the questionnaire including general information, skills background of English, difficulties in learning English, learning material expectation, and learning process Expectation. The results of the study narrowed to a conclusion that respondents were generally teenagers aged 15-18 years who had difficulties in speaking and pronunciation, and lacked environmental support but had great motivation to achieve English language independence in a short time without disturbing their activities in formal education. Therefore, respondents in general were more likely to follow the crash course program which was divided into small groups of at least 1 to 3 months.