bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Keluarga Dengan Kepatuhan Minum Obat Pada Pasien TB Di Wilayah Kerja Puskesmas
Authors: Zulkahfi Zulkahfi , Hadi Irwan , Halid Sopian , Maliki Imam
Published: September 2024

Tuberculosis (TB) is an infectious disease with the highest death cases in the world. One of the things that causes is the low role of the family in drug adherence. This study aims to determine the relationship between family roles and medication adherence in TB patients. The design used in this research is an analytical correlation with a retrospective approach. The number of samples in this study is 37 respondents. The results of the chi square statistical test obtained a p value = 0.0005 or p < 0.05. H1 is accepted and H0 is rejected which means there is a relationship between the role of the family and adherence to TB medication the recommendations that can be given are the provision of counseling and health promotion activities about the importance of family support for the success of OAT therapy treatment.
Kejadian Anemia Pada Ibu Hamil Trimester I Terhadap Status Hiperemesis Gravidarum Di Wilayah Kerja PKM Bambu
Authors: Susanti Susanti , Parwati Dewi , Musdalifah Musdalifah , Irma Irma
Published: September 2024

Anemia is a disease that can occur during pregnancy due to the mother's iron deficiency. Mothers who have insufficient knowledge about the benefits of iron will show behavior that is not as recommended, so complete information about the benefits of iron is needed. Hyperemesis gravidarum can cause disruption to daily activities, thereby endangering the health of the fetus and mother, and can even cause death. 6. Apart from that, nausea and vomiting also have a negative impact on pregnant women, often occurring in the morning, and can even occur at any time or sometimes occur at night. 40-60% of these symptoms usually occur in multigravidas. The aim of this PKM is to determine the relationship between nutritional status and hyperemesis gravidarum with the incidence of anemia in pregnant women in the first trimester at PKM Bambu. The service method begins with educational activities carried out by providing material, symptoms and preventing anemia in pregnant women. Providing education about anemia provides an initial understanding of the impact of anemia. The second activity was carried out after providing education by carrying out early detection of anemia through Hb examination. The third activity is nutritional counseling which will be provided by a nutritional counselor. Sampling used a total sampling technique, namely a sampling technique whose number was the same as the population with a sample size of 30 respondents. Based on the results of a questionnaire that was carried out on 30 pregnant women in the first trimester who experienced anemia at PKM Bambu, some data was obtained about the characteristics of respondents based on age and employment status. There is a positive relationship between X1 (nutritional status) and Y (the incidence of anemia in pregnant women) and it is statistically significant.
Pendampingan dan Sosialisasi dalam Pemberian Edukasi dengan Leaflet (brosur) Penggunaan Obat Tetes Telinga
Authors: Suminar Saka , Utami Yuri Pratiwi , Surya Sara , Mustarin Rahmah
Published: September 2024

Various drug-related problems can be caused by the community's lack of understanding about the use and proper handling of drugs. Providing education on how to use special drugs such as ear drops is very important because there are critical points in ear drops, especially in the method of instillation. Providing incomplete and unclear information on how to use drugs will result in less than optimal therapy so that the drug will not achieve the desired therapeutic effect. This community service activity aims to increase public knowledge about how to use ear drops properly. This service is carried out by providing information through leaflets and explaining directly to the community. Providing education on how to administer ear drops to the community received a good response because most people do not know how to use them properly. The presence of 36 participants and the participants who attended were very enthusiastic in listening to the explanation and actively asked questions related to the use of ear drops and their handling. This can support the realization of government programs in improving health services for the community. This counseling received significant results. Therefore, the PkM TEAM hopes that with this counseling, it can share information about the correct use and handling of ear drops with their family members.
Sosialisasi dan Penyuluhan Kesehatan Penanganan Pertama Luka Terbuka Pada Anak Usia Dini
Authors: Tawil Muh. Risal , Tarigan Nanarita , Ali St. Aminah , Fahamsya Arifina , Alfiraza Ery Nourika , Syahrir Muhammad
Published: September 2024

Open wounds are a type of wound that is exposed to air due to skin damage without or accompanied by damage to the underlying tissue. Types of open wounds are abrasions (abrasion or excoriation), incised wounds or incised wounds (vulnus scissum), torn wounds (laceration or vulnus laceratum), stab wounds (vulnus punctum), bite wounds (vulnus morsum), gunshot wounds, burns (combustion).  Early childhood are those who are in their growth period. During their growth period, it is not uncommon for them to be very active and explore new things. While exploring, some of them may fall, slip, get scratched and get wounds on their hands, foreheads or feet. The aim of community service is to provide education to the public about the types and procedures for initial treatment of wounds, as well as things that must be done and what must be avoided so that wound healing can be maximized. The method used is socialization and health education on the first treatment of open wounds in early childhood using observation and approaches through pre-test and post-test. The results achieved show that children's knowledge has increased and they know the steps for dealing with open wounds, which was proven during the question and answer session, children were able to mention how to handle open wounds in the correct order. The conclusion is that socialization of appropriate initial treatment is very necessary to prevent complications and speed up the wound healing process.
The Role of Punjab Public School Support Program in Enhancement of Enrollment
Authors: Shahid Iqbal Khan  , Dr. Asif Jamil
Published: September 2024

The enhancement of enrollment in PEIMA-financially supported PSSP schools in the Mianwali area was the main focus of the current study. Survey constructed as intended and quantitative methodology used. The study's goals were to investigate any shortcomings in PSSP schools receiving assistance from PEIMA and to monitor the improvement of enrollment in these schools. The study's population consisted of all the male and female primary schools in the district of Mianwali that were founded in the public sector and funded by the Punjab Education Initiative Management Authority under the PSSP mode. Seven hypotheses and five research questions were developed. 110 instructors and 33 principals made up the study's sample. The tool was a 5-point Likert scale questionnaire created by the researcher. Test of Validity & Reliability and Pilot testing were done before administering the instrument. This study can help the concerned authorities and implementing partners to consider study findings for recruitment & selection, training & development, performance appraisal, succession planning & infrastructure facilities, and academic achievement of the student and teacher's competencies.
Analytical study for the assessment by Independent Monitoring Unit (IMU) for monitoring teaching effectiveness and physical facilities in Secondary Schools of Khyber Pakhtunkhwa
Authors: Muhammad Arshad Khan  , Dr. Assim Saeed  , Prof. Dr. Muhammad Shah
Published: September 2024

This study endeavors to find quality assurance in schools monitoring measured by the Independent Monitoring Unit (IMU) which covered critical areas of interventions and requires independent monitoring on monthly basis to track progress. This plan also sets out a series of interventions and reforms that will support the attainment of the objectives like teacher’s attendance and enhancing teaching skills. The main objectives of the study were; 1) To find out the quality assurance of school monitoring by this Independent Monitoring Programme. 2) To assess the teaching effectiveness and effective use of ICT. 4) To assess the physical facilities of schools. 5) To assess the Support establishment of performance monitoring mechanisms. 6) To assess the increase retention and reduction of dropout with improved teaching, learning and with less teacher absenteeism. Null Hypothesis entail that there is no significant effect of IMU Programme in promoting effective teaching by teachers whereas Alternate Hypothesis reflects that there is a significant effect of IMU in promoting effective teaching by teachers. The study was perception based work whereas three stakeholders i.e. Head Masters, Teachers and Students were selected for this research study. The population of the study was all Government High schools Boys and Girls of the Khyber Pakhtunkhwa. Total six girls and boys schools were selected, out of these, sample of 50 (40 from Students, 08 from teachers & 02 from Head Masters) taken from each school. Thus total numbers of sample was 300. Name of selected schools were:- 1) GHS Boys Kirri Khesure lie at most northern part of D.I.Khan. 2) GHS Boys Parova lie at the most southern part of D.I.Khan. 3) GHS Boys Kachi Paind Khan situated in D.I.Khan city. Whereas three selected GGHS were:-1) GGCMHS No.1 lie in the heart of City. 2) GGHS Wanda Madad 35 Kilometer away from D.I.Khan City at North side. 3) GGHS Behari Colony, Zafarabad, D.I.Khan. It is concluded that IMU is a systematic and planned monitoring programme. Main focus was given to teacher’s absenteeism. This programme may also extend to measure other dimensions like school physical facilities, teacher’s competencies, students drop out and their retention etc.
When Learning Counts: Rethinking Licenses for School Leaders
Authors: Adams Jacob E. , Copland Michael A.
Published: September 2024

A national report examines how states can rethink their systems for licensing principals to better support learning goals.
Quality Measures: Principal Preparation Program Self-Study Toolkit—12th Edition
Authors: King C.L.
Published: September 2024

This self-assessment toolkit can help principal preparation program leaders and others assess the quality of pre-service principal training.
Parametrization of PHENOBMSBv.02 - A Model for Simulation of Developmental Instars of Halyomorpha halys
Authors: Lazăr Cătălin , Popescu Dan , Maistrello Lara , Costi Elena , Ichim Loreta , Georgescu Emil Igor Vlad
Published: September 2024

This paper proposes an extended parametrization for a simple model for the development of the invasive brown marmorated stink bug (Halyomorpha halys Stål, 1855) proposed by the same authors in a previous conference. The quadratic equations for the duration of each instar under variable temperatures were obtained by regressions of datasets from a controlled temperature experiment published by other authors. Compared with the previous version of the model, in this paper was analysed the impact on the calibration of additional three different phenological data sets available in literature. The thermal efficiency for the development of each temperature record from a data logger is given by the ratio of the minimal duration of the considered instar (duration under optimal temperature to fulfil a specific stage) and the duration of the same stage at a recorded temperature. The simulated stage is considered fulfilled when the sum of the products between record duration and its thermal efficiency is equal to the minimal duration of the consideration stage. The model was tested with experimental data obtained from a life table study performed in cages under outdoor weather conditions in the Emilia Romagna region in 2015.
Experimental and Numerical Approaches to Optimize Heat Blocking Efficiency in Intumescent Coatings
Authors:   Macromolecular Science and Engineering, Case Western Reserve University,, Hafiz Taher , Covello James ,   Macromolecular Science and Engineering, Case Western Reserve University,, Wnek Gary ,   Macromolecular Science and Engineering, Case Western Reserve University,, Liao Ya-Ting ,   Mechanical and Aerospace Engineering, Case Western Reserve University,, Gassama Edrissa ,   Equity Engineering Group, Research and Development, Melaiye Abdul Kareem ,   Goodyear Tire & Rubber Company, Research and Development
Published: September 2024

Intumescent coatings, which swell and form a protective char when exposed to flame, are key for fire protection. This study evaluates the Heat Blocking Efficiency (HBE) of epoxy resin coatings, incorporating eco-friendly tannic acid (TA) and ammonium polyphosphate (APP) on hot-rolled carbon steel (HRCS). Using a methane torch, a 6.3-mm thick HRCS plate was subjected to 130 kW/m2 heat flux. To predict heat transfer and estimate HBE, we combined experimental methods and numerical simulations involving a two-dimensional heat conduction model via finite element analysis (FEA), considering thermal insulation, heat flux boundary conditions, convection, and radiation. The results aligned closely with experimental data, confirming the coatings' efficacy in keeping steel temperature below the critical range of 550-600°C for up to 20 minutes, with the minimum temperature observed under 250°C. The coatings' HBE successfully reduced the substrate temperature by 90%, demonstrating their potential for advancing fire safety in coatings technology.
ՀԱՐԿԱՅԻՆ ԾԱՌԱՅՈՂՆԵՐԻ ԱՇԽԱՏԱՆՔՆԵՐԻ ԳՆԱՀԱՏՄԱՆ ՀԻՄՆԱԿԱՆ ՍԿԶԲՈՒՆՔՆԵՐԸ ՀՀ-ՈՒՄ / BASIC PRINCIPLES OF ASSESSMENT OF THE WORK OF TAX SPECIALISTS IN RA
Authors: Frangulyan Mher
Published: September 2024

In the context of the formation of an effective tax system in RA, the assessment of the work of tax officials as personnel performers of tax functions in the tax system, has an undeniable role and importance. The purpose of the latter is to determine the effectiveness of the implementation of tax functions by tax officials, which will give an opportunity to understand to what extent the implementation of this or that tax function by tax officials is appropriate, necessary or provides the desired result. As any evaluation process, the evaluation of the work of tax officials must also be carried out with the observance of certain principles, which is aimed at ensuring the objectivity, fairness and efficiency of the evaluation process. In this regard, the article presents the main principles that need to be taken into account and maintained in order to more objectively evaluate the work of tax officials in the RA tax system, contributing to the formation of an effective tax system. Therefore, first of all, the principles were taken into account, by the application of which, the evaluation of the work of tax officials in RA will enable to identify the problems arising during the implementation of tax functions and to exclude the implementation of such functions, which are not aimed at increasing the efficiency of the tax system.
Linking Patient Safety Culture, Job Satisfaction, And Nursing Care Quality: Evidence From Private Hospitals
Authors: Asroriyah Zulia Khozanah  , Irviana Fitriyati
Published: September 2024

Patient safety and nursing care quality are two crucial aspects of healthcare delivery. Todays, ensuring a robust patient safety culture is fundamental to achieving high standards in nursing care. This present study aims to investigate the relationship between patient safety culture and nursing care quality. In addition, job satisfaction assessed as mediating variable. Using convenience sampling technique, a total of 236 nurse participated in the survey during February until April 2024. The respondents are nurses who works in private hospital, located in Tangerang. SPSS 26 is employed as a statistical tool to assess path analysis. The result showed that patient safety culture has a positive influence on nursing care quality. Patient safety culture also shares positive effect on nurse’s job satisfaction. In addition, based on the sable test result, job satisfaction significantly mediates the connection between patent safety culture and nursing care quality. These findings suggest that enhancing patient safety culture not only improves the quality of nursing care but also boosts nurses’ job satisfaction. Therefore, interventions aimed at strengthening patient safety culture can provide dual benefits in improving healthcare outcomes.
Penerapan Senam Dismenore Pada Remaja Putri di Kecamatan Sukarami
Authors: Putu Mae Lovenya  , MK Fitriani Fruitasari  , Novita Anggraini
Published: September 2024

Dysmenorrhea is a gynecological complaint resulting from an imbalance of the hormone progesterone in the blood, resulting in pain. The impact of menstrual pain is very diverse, including young women being unable to walk, having difficulty sleeping, being in a bad mood, losing concentration in doing something, and so on. Gymnastics is a relaxation technique for experiencing dysmenorrhea. To find out nursing care for adolescents with reproductive disorders, dysmenorrhea, the design used in this scientific report is a case study. This case study results from the application of Evidence Based Practice (EBP), client K experienced moderate dysmenorrhea pain on a scale of 4 after being given the intervention, decreasing to mild pain on a scale of 2, client R experienced mild dysmenorrhea pain with a pain scale of 3 after being given the intervention, decreasing to mild pain on a scale of 1 and client S experienced mild dysmenorrhea pain with a pain level of 3 after being given the intervention, decreasing to no pain on a scale of 0. Applying Evidence Based Practice (EBP) it can be concluded that dysmenorrhea exercises can reduce the dysmenorrhea pain experienced by young women during menstruation.
Study of antimicrobial activity of Thymus vulgaris extract Against bacterial acne vulgaris.
Authors: Sura S Talib
Published: September 2024

One of the most significant species in the Lamiaceae family, thymus vulgaris isendemic to the Mediterranean region and is used widely for both medicinal andculinary purposes. this study aims to evaluate the use of natural antimicrobials asan alternative therapy because the long-term use of antibiotics in the treatment ofacne has resulted in the formation of resistance. It may be inferred that Thymusvulgaris (T. vulgaris) extracts have the ability to suppress the test bacteria in theplan, indicating that they may be used as antimicrobial agents against pathogenicbacteria.
Knowledge, Attitude and Practice Of Self Medication (Self Drugs Prescription) Among Students In Al-Qadisiyah University/ College Of Medicine
Authors: Israa Mahmood Abd Al-Zihra  , Fatima Abd Alkathem Redha Alkhalidi
Published: September 2024

Background: Self-medication is defined as using medicinal products to treat the disorders or symptoms diagnosed by oneself, Self-Medication is common practice worldwide in both developed and developing countries, Regulations usually distinguish between prescription-only medicines (POM) and over the counter (OTC) drugs. inappropriate self-treatment can pose various risks including drug side effects, recurrence of symptoms, drug resistance, etc. the purpose of this study was to investigate the knowledge, attitude, and practice of medical students towards self-medication.  Subjects and Methods: A cross-sectional study was carried out among five stages that were selected by the simple random sampling for choosing the students. Data collections were performed from the beginning of March to October 2023. Data were collected with A four-part researcher questionnaire. It was designed to address the students’ knowledge, attitude, and practice. Statistical analysis was performed using Statistical Package for the Social Sciences 23 software. Results: Out of 462 questionnaires distributed, 445 questionnaires were completed; giving a response rate of 96.3%. According to the results, 310 (69.7%) students had carried out self-medication within the past one year. Common cold was the most common ailment treated with self-medication (73.9%) and antipyretics analgesics (64.5%) were the most used drugs. The primary information sources used by the students were their academic knowledge and books (47.4%). Health problems are not serious the most reason for self-medication in the study and lack of knowledge about medicine the highest causes for not taking medication. Conclusion: students’ knowledge of self-medication appears to be good and significantly high. As well self-medication was highly practiced among the students. Therefore, medical students should be viewed as important contributors to the public health care system, and future health professionals should be properly educated on good pharmacy practice and responsible self-medication.
The role of Tenascin-X, Paraoxonase 1 and some other biochemical parameters in infertility women
Authors: Yasameen Abdulhuussien Salman  , Saif. M. Hasan  , Nagham Qasim Kadhim
Published: September 2024

The thyroid interact with the hypothalamic-pituitary reproductive axis. Tenascins (TN) are a group of versatile glycoproteins found in the extracellular matrix (ECM) that have distinct expression patterns in different tissues and stages of development, as well as in homeostasis tissue balance and during infections and diseases. Furthermore there  are   four types of  family members that are referred as  tenascin (-C,-R,-X, -W).Tenascin-X and tenascin-C have significant involvement in human diseases. The paraoxonase family consists of three genes: paraoxonase 1, paraoxonase 2, and paraoxonase 3. These genes have around 70% genetic sequence similarity and 60% same sequence of amino acid. Materials and Methods: 120  Sample of the current study were collected from married women aged 20 and 45 years after taking their information (age, height, weight, and health status in detail) to obtain suitable samples.  Results : The anti-mullerian hormone showed significant decrease at (P<0.01) in hypothyroidism and increase significant in infertility at (P<0.01). Prolactin showed highly increase significant in hypothyroidism at (P<0.01) and in infertility women patients compared with women control . Luteinizing hormone level showed increase significant in hypothyroidism and infertility at (P<0.01)  and follicle-Stimulating hormone level showed decrease significantly .The tenascin-X showed a high significant increase at (P<0.01) in  hypothyroidism patient compared with control group. The optimal cut-off value tenascin-X was (10.382 pg/ml as cut-off value). The tenascin-X showed a high significant increase at in infertility with hypothyroidism women patient compared with control group. The optimal cut-off value for tenascin-X was (8.904 pg/ml) . Albumin level showed decrease significant in hypothyroidism at (P<0.01) and increase significant in hypothyroidism and infertility patients at (P<0.01) with control group. Conclusions: Hypothyroidism is associated with changes in the level of sex hormones, which is one of the main causes of infertility . tenascin-X were related with hypothyroidism. Hypothyroidism is associated with oxidative stress, PON-1conseder anti-oxidant and activity is changes in oxidative stress of different etiology.
The Effect of Some Heavy Metals on Kidney Tissue and Function
Authors: Asmaa Khalid Matni
Published: September 2024

This research tested the effect of cadmium chloride and lead acetate on kidney function and their impact on kidney tissues. The study included (30) white rats that were randomly divided into (6) groups:- The control group takes plain water orally for 30 days, the group that was given CdCl2 (5 mg/kg) of body weight, the group that was given CdCl2 10 mg/kg of body weight, the group that was given lead acetate 50 mg/kg of body weight, the group that was given lead acetate 100 mg/kg of body and the group that was given cadmium chloride 5mg/kg with lead acetate 50 mg/kg body weight with drinking water for a month .The results shown in Table (1) indicated a significant increase (P < 0.05) in the levels of urea, creatinine, and uric acid in the serum of groups treated with CdCl2 at doses of 5 and 100 mg/kg, and the groups treated with lead acetate at doses of 50 and 100 mg/kg, as well as the group that received CdCl2 at a dose of 5 mg/kg along with lead acetate at a dose of 50 mg/kg, comparison with the healthy group .As for histological sections, the results showed the following section of the renal of the group treated with cadmium chloride 5 mg/kg shows atrophic renal glomerulus, necrosis of cells lining Bowman’s capsule , necrosis of cells lining the convoluted tubule  and a large increase in the space between the glomerulus and the capsule. As for the group treated with high-dose cadmium chloride showing necrosis of cells lining the glomerulus  and degeneration of cells lining the renal tubules Fragmentation of the glomerulus. As for the group treated with lead acetate at a dose of 50 mg/kg showing renal glomerulonephrosis, proximal and distal convoluted tubule necrosis, and periglomerular space in an almost normal manner. A section of the kidney of the group treated with with high-dose lead acetate, showing atrophy of some renal glomeruli and congestion of blood vessels and showing blood congestion within the kidney tissue, and decomposition of the cells lining the urinary tubules , Cross-section of the kidney of the group treated with cadmium chloride 5 mg/kg and lead acetate 50 mg/kg body weight Shows destruction of renal glomeruli  and swelling of renal tubule cells and necrosis of the kidney tissue with the appearance of hemorrhage Comparison with the healthy group
Pengaruh Pemasaran Digital, Kualitas Layanan Elektronik dan Citra Merek terhadap Keputusan Konsumen Menggunakan Aplikasi Ovo
Authors: Nurul Sriminarti
Published: September 2024

The behavior of digital wallet users in Indonesia depends on individual preferences, user habits, and other factors. Consumers' decisions in using digital finance applications are influenced by various factors, including digital marketing, the quality of electronic services and the brand image of the digital finance applications they use. This research aims to determine the influence of digital marketing, electronic service quality and brand image on consumer decisions to use the OVO application in the Jabodetabek area. The method used in this research is a quantitative method that is associative. Data was collected using a questionnaire distributed via Google Form to 155 respondents who used the OVO application. The sampling technique uses purposive sampling. Data processing in this research used the IBM Statistical Package for the Social Sciences (SPSS) ver.25. Based on the results of hypothesis testing, it shows that: (1) digital marketing variables have a positive and significant effect on consumer decisions to use the OVO application (2) electronic service quality variables have a positive and significant effect on consumer decisions to use the OVO application (3) brand image variables have a positive and significant effect on consumer decisions to use the OVO application and (4) digital marketing variables, electronic service quality and brand image together have a significant influence on consumer decisions to use the OVO application.
The Impact of Infrastructure Development, Education, Tourism, and Agriculture on Regional Economic Growth in Indonesia
Authors: Yusuf Iskandar  , Kurniawan Kurniawan  , Alzetrho Baja Pratama  , Yana Priyana
Published: September 2024

In order to better understand the complex links between infrastructure development, education, tourism, agriculture, and regional economic growth in Indonesia, this study uses structural equation modeling with partial least squares, or SEM-PLS. The research makes use of a 287-observation dataset and applies rigorous measurement model evaluation, bootstrapping analysis, structural model estimation, and model validation against multiple fit indices. The results show a strong positive correlation between each sector—agriculture, tourism, education, and infrastructure development—and regional economic expansion. The necessity for comprehensive, integrated development strategies is highlighted by the interconnectedness of these interactions. In order to promote balanced and resilient regional economic growth, the findings provide policymakers with useful insights and highlight the significance of ongoing investments in infrastructure, education, and sustainable tourism and agricultural practices.
Peningkatan Seal Online Player Loyalty: Peran Experiental Value, Promosi, dan Player Satisfaction (Seal Online Gladius)
Authors: Bayu Adhi Nugroho  , Andriya Risdwiyanto
Published: September 2024

Information technology (IT) plays an important role in supporting various aspects of modern life and industry. This research used quantitative methods with purposive sampling technique for sampling. Respondents were taken from members of the Seal Online Gladius community in an application called Discord totaling 298 members with a sample of 58 respondents. The research results showed that the contribution of the independent variable influence to the dependent variable was 13.8%, while partially the experiential value and the promotion did not have a significant effect on players’ loyalty. However, the player satisfaction has a significant effect on their loyalty.
Análisis crítico de la irrenunciabilidad de los derechos laborales en mediación en Ecuador.
Authors: Durán- Chávez Carlos Eduardo , López- Alarcón Edison Israel
Published: September 2024

En esta investigación se analizan algunos criterios normativos, doctrinarios y jurisprudenciales relacionados con el principio de irrenunciabilidad de los derechos laborales y su relación con la mediación como método alternativo de resolución de conflictos que se aplica en Ecuador. Se trata de una investigación teórica, jurídica y analítica. Como principal resultado se refiere que la Corte Nacional de Justicia del Ecuador ha resuelto mediante sentencia que los derechos laborales son irrenunciables, más no los beneficios laborales (distintos a los derechos), considerando que estos últimos son aquellos que no están previstos en la Constitución de la República y el Código de Trabajo. Lo desarrollado por la Corte Nacional de Justicia constituye un desconocimiento de principios laborales tales como: el principio de irrenunciabilidad de derechos, el principio de intangibilidad de derechos, el principio protector, así como el desconocimiento de derechos adquiridos y otros que surgen de diversas fuentes del Derecho Laboral.
O QUE REVELAM OS INDICADORES DA CIDADE GUARAPUAVA/PR? UM CAMINHO PARA UMA CIDADE INTELIGENTE E SUSTENTÁVEL
Authors: Maria Izabel Ramos  , Chiusoli Claudio
Published: September 2024

O objetivo é levantar indicadores de Guarapuava-Pr comparando os anos de 2022 e 2023, com base no Ranking Connected Smart. A metodologia adotada é considerada como descritiva e qualitativa mediante dados secundários, examinando 75 indicadores em 11 eixos temáticos que se refere a Educação (11), Mobilidade (10), Meio Ambiente (8), Urbanismo (7), Economia (7), Tecnologia e Inovação (6), Saúde (6), Empreendedorismo (5), Segurança (5), Governança (5) e Energia (4). Os principais achados na pesquisa revelam mudanças em diferentes eixos. Observa-se que tiveram os melhores desempenhos os eixos economia (71,4%), saúde (66,7%) e educação (54,7%). Os resultados sugerem um desenvolvimento da cidade e crescimento importante na qualidade de vida dos cidadãos. Como contribuição é possível que esses indicadores se tornam importantes para orientar a gestão pública com políticas e investimentos com a proposta de um desenvolvimento sustentável a caminho para uma cidade inteligente.
ANÁLISE DE MARCADORES SOROLÓGICOS DE AUTOIMUNIDADE NO LÚPUS ERITEMATOSO SISTÊMICO: ASSOCIAÇÃO COM MANIFESTAÇÕES CLÍNICAS
Authors: Maiara Bortoli Rodrigues  , Laura Marostica Brustolin  , Isabella Cristina Michelon  , Rafael Rauber  , Diogo Cunha Lacerda
Published: September 2024

Introdução: O Lúpus Eritematoso Sistêmico (LES) é uma doença crônica autoimune que pode acometer diversos órgãos e sistemas, apresentando-se com manifestações clínicas diversas. A classificação e o diagnóstico são estabelecidos a partir de sinais e sintomas observados e análises laboratoriais de marcadores imunológicos. Existem correlações conhecidas entre esses marcadores e as manifestações clínicas relacionadas nos critérios classificatórios de LES, todavia, ainda não completamente exploradas. Objetivos: o objetivo deste estudo foi avaliar a associação dos marcadores sorológicos de autoimunidade em pacientes com diagnóstico de LES com as manifestações clínicas presentes nos critérios classificatórios da doença. Métodos: trata-se de um estudo transversal, retrospectivo e observacional, a partir de prontuários eletrônicos de pacientes com diagnóstico de LES em um centro especializado de Cascavel-PR. Uma análise estatística descritiva foi conduzida para avaliação da associação entre a presença e ausência dos diferentes sintomas e a atividade ou não dos diferentes anticorpos. Foi aplicado o teste de Qui-quadrado de independência, seguido do pós-teste de resíduos ajustados, quando necessário, sendo que para as diferentes manifestações, foi considerado o critério de exclusão para aquelas que acometeram menos que 35% da amostra considerada. Foram considerados significativos apenas os dados com p-valor
Further Observations in Wiper design and Particle Transport Simulation in the Sealing Gap
Authors:   Freudenberg FST GmbH, Barillas Gonzalo A. , Gropp Andreas
Published: September 2024

"In the last ISC results with several wiper designs with regards to dirt insert rate into a sealing system was presented. Also, the simulation of the motion of such particles in the sealing gap was shown. Material wear resistance and fluid streamlines before the lip seems to have an influence on particle’s ability to pass the gap between seal and rod. In this paper, starting from a standard wiper, lip design alterations were tested. By changing the wiper’s lip design a change in the flow lines of the fluid and therefore the particle insert rate was intended. Among the lip design changes furthermore the improvement in simulation of particle flow in the wiper-rod interaction area is presented. The effects of the lip variation on the particle insert test results will be discussed and compared with simulation results."
Stochastic analysis on tribological behavior of radial shaft seals with focus on lubricants
Authors:   TU Bergakademie Freiberg, Institute for Machine Elements, Design and Manufacturing (IMK, Lin Yongzhen , Nepp Ringo , Kröger Matthias , Haupt Stefanie
Published: September 2024

This study deals with a methodical interpretation into the complex landscape of the tribological behavior of Radial Shaft Seals (RSS) using dynamic investigations focusing on the influence factor lubricant. The RSS forms a tribological system with the shaft surface as counterpart and the applied lubricant as medium. The lubricant has been identified as one of the main drivers for the tribological behavior of RSS especially due to its chemical structure and physical viscosity. Previous research has shown that the tribological behavior of RSS, such as leakage or wear, can be observed during and after testing with different lubricants, especially with different viscosities. This study evaluates the impact of lubricants with different chemical structure but similar viscosity, which allows to gain a deeper understanding of the further properties of lubricants. More specifically, different kinds of lubricants have been analyzed on RSS with different materials and diameters. Thereby, the rotational speed has been varied in relevant ranges. Using stochastic calculus analysis, the tribological behavior of RSS with lubricants can be evaluated in more detail. Especially, the variance of the frictional moment of the seal can be analyzed and interpreted depending on the test conditions. Secondly the potential damage and the wear formation can be evaluated optically with a microscopy. These results not only contribute to the academic discourse on RSS and lubricants as well as the tribological system, but also classify the different operating combinations for real applications. A specially designed RSS test rig at the Institute for Machine Elements, Design and Manufacturing is available for the experimental investigations. The aim of the extensive investigations is to create a basis for future, more in-depth research into understanding on the tribological behavior of the RSS as well as predictions for specific classified working environment for the different RSS systems.
Frictional characteristics of elastomeric radial lip seals at extremely low temperatures
Authors:   Leibniz University Hannover, Institute of Machine Design and Tribology (IMKT), Amro Mousa , Wennehorst Bengt , Poll Gerhard
Published: September 2024

A novel low-temperature radial lip seal test rig was set up, allowing for simultaneous non-contact, telemetric measurements of both radial lip seal contact temperature and seal friction torque. Extreme cooling of the sealing contact zone down to below -50 °C was achieved by continuously feeding carbon dioxide snow pellets into the bore of a hollow seal counterface adaptor. Though this setup enables a simultaneous evaluation of two identical test seals, where the inner space is filled with lubricant, in this work, the frictional characteristics of wetted, single test seals were investigated. This eliminates the churning losses of the oil-filled ring gap that, due to the drastic increase of the lubricant viscosity at low temperatures, would severely hinder the correct determination of the seal friction torque. Experiments were conducted with plain radial lip seals made of NBR and FKM, using two polyglycol oils with different viscosity grades VG 220 and VG 46, respectively. Starting from a stationary state at 100 rpm (0.419 m/s) with contact temperatures in the range of 45 °C to 60 °C, the sealing contacts were subsequently cooled down, finally reaching steady state seal contact temperatures as low as approx. -50 °C. Thus, during cool-down of the sealing systems, both seal elastomers pass through the glass transition, and both lubricants pass through their pour points. In contrast to warm operating conditions, where speed-step dependent seal friction changes could be accurately predicted based on soft micro-elastohydrodynamic asperity lubrication theory, speed step experiments at such extremely low temperatures revealed that there was no viscous friction response, i. e. the seal friction was due to Coulomb-type friction. While showing larger fluctuations, the overall level of this Coulomb-type friction was comparable to the steady-state seal friction measured under warm operating conditions. When warming the systems up, the original lubrication mode was reestablished.
Functional testing of additively manufactured hydraulic rod seals
Authors: Ebel Thomas , Ottink Kathrin , Graf Matthias , Lankenau Tobias
Published: September 2024

"Hydraulic rod seals are crucial machine elements in a lot of applications. Malfunction of rod seals can cause huge economic loss by long shutdown times for repair. Especially if equipment is used in remote areas in the nature, malfunction can also cause severe environmental damage by spilled polluting hydraulic fluid. The delivery time of dynamic rod seals for hydraulic applications can last weeks or even months as these seals are often manufactured on demand. In addition, the last years have shown that also geopolitical incidences like a war or a pandemic can have a huge impact on international channels of trade. In order to avoid, or at least minimize, machine shutdown times, it seems to be desirable to have local production solutions for rod seals by using easy to handle machinery and a single, simple raw material. A possible solution to circumvent delivery challenges can be the use of an additive manufacturing (AM) method. The research question addressed in the presented study is whether it is possible to produce functional rod seals using simple AM methods. The results of the method screening and the preliminary investigations were presented at the 21st International Sealing Conference in Stuttgart in 2022. One of the results was the choice of Fused Filament Fabrication (FFF) as the additive manufacturing method for the study and thermoplastic polyurethane (TPU) as the material class to be used. Our latest results, the outcomes of two series of functional tests conducted with these different filaments, will be the core of the presentation that we plan to give at this year’s conference. Parts that are produced by using the Fused Filament Fabrication method are never fully dense due to the process. Nevertheless, the functional tests conducted on a rod seal test rig showed that the research question can be answered in an affirmative way for tested pressures up to 15 MPa. Even in a long-term test the function of the additively manufactured seals met the demands."
The impact of social restrictions on the incidence and microbiology of severe acute tonsillitis
Authors: Sørensen Thomas Lynge , Greve Thomas , Klug Tejs Ehlers
Published: September 2024

INTRODUCTION. We aimed to explore the impact of social distancing on the incidence, severity and microbiology of patients with acute tonsillitis (AT). METHODS. In this single-centre study, we retrospectively included all patients with AT referred to the Ear-Nose-Throat Department, Aarhus University Hospital, Denmark, in the two years preceding versus the two years after the COVID-19 lockdown in Denmark (11 March 2020). RESULTS. In total, 425 patients were included. The incidence of AT was significantly lower in the post-lockdown period (n = 128) than in the pre-lockdown period (n = 297) (p < 0.001). Reduced incidence was observed across all age groups. No significant differences were found in patient characteristics between periods. The proportion of hospitalised patients was significantly lower in the post- than in the pre-lockdown period (36% versus 25%, p = 0.032). Prevalent culture findings were Streptococcus pyogenes (15%), S. anginosus group (11%) and Fusobacterium necrophorum (5%). No statistically significant differences in the relative prevalence of individual bacteria were found between periods. CONCLUSIONS. The incidence of patients with AT referred to hospital decreased by 57% in the two-year period after the COVID-19 lockdown compared with the period leading up to the lockdown. Our findings suggest that this decrease mirrored a general decline in AT incidence rather than altered referral patterns. FUNDING. None. TRIAL REGISTRATION. The study was approved by the Danish Data Protection Agency (#1-16-02-134-23) and the Danish Patient Safety Authority (#1-45-70-41-23).
Perspectives of patient and public partners on their involvement in research
Authors: Jacobsen Birgitte Gade , Grønkjær Lea Ladegaard , Locock Louise , Ploug Magnus
Published: September 2024

INTRODUCTION. Patient and public involvement (PPI) in research integrates patient and public perspectives to improve research relevance and quality. The experiences of PPI partners have revealed mixed findings in countries where PPI is well established, but accounts from areas less accustomed to PPI in research are limited. This study aimed to explore the knowledge, motivations, expectations and experiences of PPI representatives in such a setting. METHODS. This was a qualitative study based on semi-structured interviews. Patient and public partners who had recently been engaged in a PPI collaboration to redesign the written patient material for a clinical study were interviewed. The interviews were analysed using inductive content analysis in which quotations were extracted, coded, categorised and interpreted into themes. RESULTS. Interviews indicated a lack of knowledge concerning PPI in research. Despite their motivation to collaborate, the PPI partners expressed anxiety and doubts about their abilities as laypeople. A sense of societal obligation to collaborate was noted. Groups-based, repetitive sessions fostered productivity, while challenges included off-topic discussions and skepticism. CONCLUSIONS. The findings provide valuable insights for shaping PPI processes and recruitment strategies in regions that are new to PPI. This highlights the need to describe the PPI concept when recruiting participants elaborately and to utilise repetitive group-based sessions in the design. FUNDING. Supported by the Novo Nordisk Foundation and the Chief Scientist Office, Scotland. TRIAL REGISTRATION. Not relevant.
The prognosis of schizophrenia
Authors: Starzer Marie , Hansen Helene Gjervig , Hjorthøj Carsten , Albert Nikolai , Nordentoft Merete
Published: September 2024

Psychotic and negative symptoms are core features of schizophrenia but knowledge on the long-term course of these symptoms is lacking. While antipsychotics improve psychotic symptoms, they have limited effect on negative symptoms. Specialized early interventions like OPUS show great effects while ongoing but long-term follow-up indicates no lasting disease-modifying effects. 18% of patients achieved clinical recovery, and 40% obtained symptom remission after 20 years, but high mortality rates and continuous negative symptoms constitute an unmet treatment need, as argued in this review.
Severe poisoning with semi-synthetic cannabinoids
Authors: Reiter Nanna , Linnet Kristian , Andersen Natasja Østermark , Rasmussen Brian Schou , Nielsen Marie Klose , Eriksen Karen Reenberg , Palmqvist Dorte Fris
Published: September 2024

Recently, semi-synthetic cannabinoids have entered the illegal market and are produced to mimic the psychoactive effects of tetrahydrocannabinol (THC). This is a case report of a 19-year-old man, who was hospitalized due to severe sedation, hypotension and tachy- and bradycardia after ingestion of the semi-synthetic cannabinoids hexahydrocannabinol (HHC) and hexahydrocannabiphorol (HHC-P) mixed in food. HHC-P, HHC and metabolites were identified in blood samples. The amount of semi-synthetic cannabinoids in illegal products can be high, which can explain the described prolonged clinical effects.
Hazard Effects and Mechanisms of Action of Microplastics on Health
Authors:   College of Veterinary Medicine, Yangzhou University China, China, Hussain Zahid , Ali Bhatti Sher ,   Sindh Agriculture University Tandojam, Pakistan, Chandio Muhammad Ali ,   Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Pakistan
Published: September 2024

Microplastics, particles smaller than five millimeters, have emerged as significant environmental pollutants, drawing attention due to their widespread distribution in the atmosphere, water, and soil. They enter organisms through ingestion, inhalation, and skin contact, inducing cytotoxicity, tissue damage, and compound health risks. This review systematically examines exposure pathways, health hazards, and mechanisms of microplastics, aiming to inform research on their environmental health impacts.
Role of Applied Behavior Analysis in Developing Expressive Verbal Communication in Intermediate Learners with Autism
Authors:   Walden University. Atlanta, Georgia, USA, Basu Oyindrila
Published: September 2024

Verbal behavior is a fundamental mode of communication and human interaction. Any form of obstruction in the performance of verbal behavior can lead to life-long impairment. In this paper, I want to do a literature review of four research articles, which focus on different treatment strategies based in applied behavior analysis, to improve the verbal and expressive communication of children with autism. I also want to propose a methodology for intervention based in applied behavior analysis which can improve all the different operants of verbal behavior. The proposed intervention involves a combination of visual perceptual aids, verbal shaping, stimulus fading and stimulus transfer. As my objective is to improve the communication of intermediate learners who are more functional, we can improve evidencebased music therapy as well in eveloping speech structure and consistency in learners.