bluuebunny/crossref_metadata_2025 huggingface dataset:
Psicosis tardías y fenocopias
Authors: Ollari Juan , Deschle Florencia , Rubiño Valeria , Blanco Romina , Ciufia Natalia , Delembert Walter
Published: October 2023

Los síntomas psicóticos pueden manifestarse a cualquier edad, pero en las personas mayores representan un verdadero desafío diagnóstico. Pueden observarse trastornos del pensamiento, alucinaciones (usualmente visuales), trastornos del estado de ánimo con ideas delirantes, trastornos en la interacción social y ocasionalmente agresividad verbal o física (Karon & VandenBos, 1998). Desde lasprimeras descripciones de la psiquiatría clásica se ha intentado definir a las psicosis observadas en las personas mayores y determinar si se trata de síndromes “psiquiátricos” primarios o, por el contrario, si se los puede atribuir a otras patologías. Así, han surgido diferentes conceptos, como psicosis de comienzo tardío (Late Onset Psychosis) o esquizofrenia de comienzo tardío (Late-Onset Schizophrenia – LOS), psicosis de comienzo muy tardío (Very Late-Onset Psychosis)o psicosis esquizofreniforme de comienzo muy tardío (very late-onset schizophrenia-like psychosis – VLOSL), psicosis de la vida avanzada (Late-Life Psychosis), etc.
Mechanisms of ginseng in pancreatic cancer metastasis
Authors: Wang Zhaohong , Cai Xufan , Lin Shengzhang
Published: October 2023

It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.
CHARACTERISTICS OF THE AITYS GENRE AMONG KAZAKH AND TURKISH PEOPLE
Authors: Mursаlіmovа N.M. , Oralbek А.
Published: October 2023

Aitys is a special genre that occupies a special place in our national literature. All types of aitys require eloquence, mobility, and ingenuity. In Kazakh and Turkish literature this genre is in accord with social, socio-political issues. Using jokes, humor and satire in their improvised verses two poets compose dialogue on significant changes and various social phenomena within the country. At the same time by giving a clear, rational reply to the opponent, one can be on an advantageous position. Poets also use this aitys genre of verses competition to convey their inner feelings of mood. At all times, aitys genre can be called a mirror of its era. Therefore, the study of such diverse characteristics and specific features of the aitys genre, its generality as a harbinger of social situations is considered one of the main tasks of the science of Kazakh literary studies.

Improvisational talent is the natural talent of the poet. Aitys genre requires great responsibility and deep knowledge in different spheres. Accepting the advantages of other poets in his/her environment and advancing his/her knowledge should be considered as the stage of the poet's ascension.

Kazakh aitys genre works have more improvisational feature, have a large and artistic content, descriptive of a long chronicle about the country’s and people’s life, while the assonant rhymes of Turkish atyshma are subject to a special condition and certain rules of artistic schedule. It can be said that the basis of both theatrical and dramatic art is connected here. A characteristic feature of Kazakh and Turkish traditions is their formation in ancient times, when both nations had a common spiritual heritage and even a common stat.

Aitys is a common heritage of the Turkic people. Aytys genre is a phenomenon of the Turkic-speaking peoples culture that spread orally.

As the object of the study was selected and considered the artifacts of the ancient Turkic era, the first versions of aitys, as well as the works by folk poets of the XIX-XX centuries and the Kazakh and Turkish aitys types, which are main subjects for the research relevance.

The article analyzed deeply the division of the aitys genre into subtypes, its methods, features and similarities among the Turkic peoples based on the opinions and conclusions of Kazakh and Turkish scientists.
Las Características Asociadas A Lesiones Personales Y Sospecha De Maltrato Físico En Adultos Mayores Evaluados En La Clínica Médico Legal, 2019-2020
Authors: Flores Ariel
Published: October 2023

OBJETIVO Determinar las características asociadas a lesiones personales y sospecha de maltrato físico en adultos mayores atendidos en la Clínica Médico Legal (CML) de Calidonia del 1 de enero de 2019 al 31 de diciembre de 2020. MATERIALES Y MÉTODOS Un estudio descriptivo, retrospectivo de corte transversal. El Universo correspondía a 432casos atendidos por lesiones personales y sospecha de maltrato físico y la muestra calculada con un nivel de confianza de 95% y un margen de error de 5 % fue de 204 casos. Se tomaron los datos de los expedientes de los evaluados en la CML-Calidonia, mediante un formulario de recolección de datos y se realizó un análisis descriptivo de las variables estudiadas. RESULTADOS Las víctimas evaluadas por lesiones personales y/o sospecha de maltrato físico fueron en su mayoría de sexo masculino con un 64% (N130) vs un 36% (N74) de femeninas, con una edad promedio de 67 años (DE=6.4), con un nivel educativo de Primaria en el 30% (N61). El 14% (N 29) de los evaluados no presentaba lesiones en su anatomía, siendo el sitio anatómico más lesionado, el rostro con un 40% (N 81) seguido de los miembros superiores con 39% (N79), el mecanismo de trauma más frecuente fue contundente con un 74.5% (N52), con un peligro de vida de 1.5 % (N3) de los casos CONCLUSIONES La distribución de los casos analizados reportó: sexo masculino en un 64% vs el sexo femenino con un 34% y una edad promedio de 67 años. Las enfermedades más frecuentes fueron la Hipertensión Arterial y la Diabetes Mellitus. El mecanismo causal más frecuente de las lesiones encontradas fue el contundente en un 74.5 % y un 14% de los evaluados no presentaban lesiones traumáticas recientes en su anatomía.
Introduzione
Authors: Lima Eleonora , Maiolani Michele , Malvestio Marco
Published: October 2023

Introduzione al numero monografico La fantascienza di Primo Levi.
EFFECTS OF ORAL SODIUM BICARBONATE SUPPLEMENTATION ON NUTRITIONAL STATUS OF PATIENTS UNDERGOING MAINTENANCE HEMODIALYSIS
Authors: RAFIQ A , ARSHAD AR
Published: October 2023

To determine the oral sodium bicarbonate supplementation effects on nutritional status of patients undergoing maintenance hemodialysis. In a Medicine department at Combined Military Hospital, Peshawar, a case-control study was carried on “14-October 2021 to 14-April 2022”. It enrolled patients of ESRD on MHD with low serum bicarbonate levels. Patients were allocated into two groups: an experimental group receiving oral sodium bicarbonate and a control group receiving standard care. Parameters such as mid-thigh circumference, serum bicarbonate, and serum albumin were assessed at baseline and after 3 months, with statistical analysis performed using an independent sample t-test.   The intervention group had a notable elevation in serum bicarbonate levels (20.87±1.58 mmol/l) as compared to the control group (18.73±2.38 mmol/l) (P = 0.0001). Furthermore, it was observed that the intervention group had a noteworthy elevation in serum albumin levels after 3 months (4.40±0.28 g/l), as compared to the control group (3.77±0.30 g/l) (P = 0.0001). Additionally, there was a statistically significant rise in the average mid-thigh circumference among participants in the intervention group during the third month, in comparison to those of the control group (41.20±1.70 vs. 39.74±1.27 cm; P = 0.001). Oral sodium bicarbonate supplementation in patients on maintenance hemodialysis significantly increased serum bicarbonate level, serum albumin level and mid-thigh size.
Analisis Kompetensi dalam Meningkatkan Kinerja Pegawai pada Biro Pemerintahan dan Otonomi Daerah Provinsi Sulawesi Tenggara
Authors: Darmawan Khariq , Supriaddin Nofal , Nur Muh
Published: October 2023

This study aims to determine competence in improving employee performance in government bureaus and regional autonomy of Southeast Sulawesi Province. The method used in this study is qualitative descriptive method. The types of data used in this study are quantitative and qualitative data. The methods carried out in collecting data in this study are interviews and documentation. The informants in this study were 4 regional apparatus ranks. Data analysis techniques are data collection, data reduction, data presentation, and conclusions. The results of the data analysis show that the competence of employees at the Bureau of Government and Regional Autonomy of Southeast Sulawesi Province is good, which is assessed in terms of knowledge, expertise and attitudes is good and able to improve employee performance. The performance of employees at the Bureau of Government and Regional Autonomy is assessed by quality, quantity, punctuality, effectiveness and attendance is good. The competence of employees in improving the performance of employees of the Bureau of Government and Regional Autonomy is good. Improving employee competence through training and education, and development, workshops, seminars, collaboration with educational institutions, and the use of educational technology such as e-learning for distance learning
Pengaruh Media Flash Card Terhadap Kemampuan Memahami Nilai Sosial Kelas IV Sekolah Dasar Hang Tuah 10 Juanda
Authors: Fadhilah Nabilah Jihan , Irianto Apri , Rachmadtullah Reza
Published: October 2023

This research is motivated by students' lack of understanding of social values. Students' lack of ability to understand social values ​​is evident when students misbehave with other students, creating conflicts. The implementation of social values ​​is facilitated using flash card media, which can arouse students' interest and attention in learning social values. The purpose of this study was to determine the effect of flashcard media on students' understanding of social values ​​in fourth grade. This study uses a quantitative approach in a pre-experimental study using a single-group pre-test-post-test design. Fourth grade students participated in the current study, the sample of which was 20 children. The data collection method used was a test in the form of a pre-test, post-test and direct observation and documentation. Using a statistical analysis method with a formula is a paired sample test. Based on the results of the paired sample test, Sig (2-tailed) < 0.05 received a total of 0.000 < 0.05. Thus, when deciding for a paired sample test, one can conclude that h0 is rejected and ha is accepted. This means that it can be concluded that flashcard media affects the understanding ability of social values ​​of fourth grade students of Hang Tuah 10 Juanda Primary School
Pengembangan Media Pembelajaran Komik pada Materi Menganalisis Struktur Teks Biografi Kelas X SMK Negeri 1 Lotu
Authors: Arman Suka Damai Zega  , Riana  , Lestari Waruwu
Published: October 2023

The purpose of this research is to develop comic learning media on the material of analyzing the structure of biography text in class X SMK Negeri 1 Lotu which is valid/worthy, practical, and effective. This type of research is research and development (Research and Development). The development model used is the 4D model which consists of four stages, namely the Define stage, Design stage, develop stage, and Disseminate stage. Comic learning media developed through the validity test stage by three validators (material and content experts, linguists, and design experts), small group tests and field tests conducted in class X DPIB SMK Negeri 1 Lotu. Based on the results of research conducted by three validators/experts, comic learning media has been tested valid and feasible by 100% material and content expert validators, 100% language expert validators, and 96% design expert validators. The practicality of comic learning media in the small group test was 93%, and the field test was 94% with very practical criteria. The effectiveness of comic learning media has also been tested very effective with the percentage of classical completeness in the small group test of 100%, and the field test of 87.5%.
Pengembangan Booklet pada Materi Merangkum Buku Fiksi Kelas VII SMP Negeri 2 Gunungsitoli Utara
Authors: Yudika Rahmawani Zebua  , Riana  , Lestari Waruwu
Published: October 2023

The purpose of this study is to determine the development of Booklets on material summarizing fiction books grade VII SMP Negeri 2 North Gunungsitoli. This type of research is development (Research and Development). The development model used is the Hannafin and Peck model which consists of four phases namely needs analysis, design, development and implementation and Evaluation and Revision. This Booklet product was developed through a validity test stage by three validators (material experts, linguists, and design experts), small group tests, and large group trials. The results of data analysis, Booklet products on the material summarizing class VII fiction books have been tested valid and feasible by material expert validators in revision III 100%, linguist validators in revision II 94.2%, and design expert validators in revision II 98.4%. The practicality of Booklet in small group trials was 97.2%, and large group trials were 96.9% with very practical categories. Booklet's effectiveness has also been shown to be highly effective with an average hearing for small group trials of 84.3% and large group trials of 96.5%. Based on the results of the research above, the Booklet in the material summarizes the fiction book grade VII SMP Negeri 2 Gunungsitoli Utara which has been developed with the Hannafin and Peck model has met the requirements and is suitable for use
Pengembangan Buku Saku Berbasis Inkuiri pada Materi Mengidentifikasi Unsur-Unsur Drama di Kelas VIII SMP Negeri 2 Hiliduho
Authors: Restu Krismon Putra Zebua  , Riana  , Lestari Waruwu
Published: October 2023

The purpose of this research is to develop a decent, practical, and effective Inquiry-based pocketbook learning media. This type of research is development research using the ADDIE model which consists of analysis (Analyze), design (Design), development (Development), implementation (Implementation), evaluation (Evaluation). The research instruments used were questionnaires validating material experts, linguists, and design experts, as well as student response questionnaires and the effectiveness of student learning outcomes. The results of this research are in the form of inquiry-based pocketbook products on the material of identifying the elements of drama. Material expert assessment in revision I reached 71%, in revision II reached 96.3%, with very decent criteria. The assessment of linguists in revision I reached 82.1%, in revision II it reached 100%, with very decent criteria. The design expert's assessment in revision I was 40%, in revision II it reached 98.33% with very feasible criteria. The results of the assessment on the student response questionnaire in the small group trial obtained a score of 95.5% in the very practical category. In the field test, a score of 87.3% was obtained in the very practical category. Assessment of student learning outcomes tests obtained a percentage of classical completeness in 100% small group trials and 100% field trials with very effective criteria. From the results of the research above, pocketbooks are feasible, practical, and effective for use in the learning process.
Analisis Kesalahan Berbahasa Indonesia Tataran Ejaan Menulis Karangan Siswa Kelas VIII SMP Negeri 7 Gunungsitoli
Authors: Grace Dominggos Febrini Zendrato  , Riana
Published: October 2023

This research aims to analyze language errors in the expository essays of class VIII students at SMP Negeri 7 Gunungsitoli. This research is a qualitative descriptive study. The data for this research is the worksheet of students who wrote expository essays. The data source in this research was class VIII students at SMP Negeri 7 Gunungsitoli. The data analysis techniques used are data collection, data reduction, data presentation, and drawing conclusions. Based on the research results, it shows that spelling errors in class VIII students at SMP Negeri 7 Gunungsitoli included 104 errors consisting of: 48 errors in the use of capital letters were found, including 27 errors in usage at the beginning of sentences, 18 errors in place names, in There is 1 error in the divine name, and there are 2 errors in the title of the essay. There was only 1 error in using italics. There were 25 errors in writing derived words, including 24 errors in the prefix and 1 error in the suffix. There were 6 errors in writing the word re-form. There were 6 errors in writing prepositions found. There were 18 errors in the use of punctuation marks, including 8 errors in the use of the dot (.), 4 errors in the use of the comma (,) and 6 errors in the use of the hyphen (-).
Pengembangan Media Komik Digital Berbasis Aplikasi Canva pada Kelas III di Sekolah Dasar Negeri 064017 Medan Kecamatan Perjuangan
Authors: Aulika Riska , Gandamana Apiek , Gultom Ibrahim , Feliks Dody , Tambunan Husna
Published: October 2023

The purpose of this study is to develop digital comic media based on the Canva application, in terms of the feasibility and benefits of learning media in the research learning process used in this study is a type of research and development or Research and Development (R&D). The development of this media used procedures from ADDIE (Analysis, Design, Development, Implementation and Evaluation). The subjects in this study were 1 class teacher and 15 students who were directly involved in the teaching and learning process every day. As well as 1 material expert and 1 media expert. Data collection was carried out by means of: observation, questionnaires, interviews, and tests. The results showed that the Canva Application-Based Digital Comics media was "Very Eligible" with details of the eligibility percentage obtained from media experts of 88% with the criteria of "Very Eligible", material experts of 84% with the criteria of "Very Eligible", Education practitioners (teachers) by 94% with the criteria of "Very Practical", education practitioners (students) by 92% with the criteria of "Very Practitioner", and student learning outcomes after using digital comic media based on the Canva application have increased with the acquisition of a post-test score of 87.5% with the criteria of "Effective". Therefore, it can be concluded that digital comic media based on the Canva application on theme 6 sub-theme 2 learning 2 on PPKn class III content at SDN 064017 Medan Perjuangan District is feasible to use in the process of teaching and learning activities
Entrepreneurship Education and the Role of Technology in Driving Business Innovation
Authors: Rahayu Puspita Puji , Mayasari Isti , Fitriyatinur Qurnia , Agustina Menik Tetha
Published: October 2023

Increasing business innovation is the main key in facing increasingly fierce competition in the current era of globalisation and information technology. One factor that plays a key role in driving business innovation is entrepreneurship education. This study aims to investigate the relationship between entrepreneurship education and the role of technology in driving business innovation. This research is a literature review that uses a qualitative method approach, which means it will analyse and interpret data by relying on information and text from various sources. The study results show that entrepreneurship education and the role of technology in fostering business innovation are two elements that are highly related and mutually supportive. Effective entrepreneurship education should include technology as an integral part of its curriculum, enabling students to understand how technology can be used in various aspects of business. With this understanding, they can develop practical skills, think creatively, collaborate and innovate with the support of technology, thus being better equipped to face challenges in an increasingly digital and competitive business world. The limitation of this research is that it is a literature review, so it does not involve primary data collection or field research. Therefore, the findings are descriptive and based on existing information in the literature accessed.
Human Resource Management Strategies in Improving Lecturer Performance in Higher Education
Authors: Muhamad Lili Fadli
Published: October 2023

Higher education has a very important role in the development of society and the progress of a country. In the higher education environment, the role of lecturers or teachers is crucial in creating a quality learning experience for students. This study aims to examine how human resource management can play a role in improving lecturer performance in higher education. This research is a literature review that uses a qualitative method approach, which means it will analyse and interpret data by relying on information and text from various sources. The results of the study show that regular and continuous evaluation of human resource management strategies is an important stage in adjusting and improving the approach applied. This allows higher education institutions to continue to grow and ensure that their lecturers have maximum support in an effort to provide quality education and improve the institution's reputation
Pengaruh Literasi Numerasi Terhadap Kemampuan Komunikasi Matematik Siswa Melalui Pendekatan Saintifik Kelas V SD Negeri 0507 Latong
Authors: Mutiah Era , Harahap Nurhalimah , Lubis Rahmi Hartaty
Published: October 2023

Numeracy literacy is the ability to solve mathematical problems using various types of numbers and symbols practically. Students of SD Negeri 0507 Latong have problems understanding the story problems in the numeracy literacy assessment section, so they need a solution. This study aims to determine the effect of numeracy literacy on students' mathematical communication skills through a scientific approach grade V SD Negeri 0507 Latong. The subjects in this study were class V as many as 37 students with a simple random sampling technique. Data collected using test instruments are then processed with descriptive statistical data analysis techniques and inferential statistical analysis tests. The results of the descriptive analysis showed that the results of the values were normally distributed with the acquisition of the average value of the variable (X) which was 82.97 which was in the medium category and the acquisition of the average value of the variable (Y) 88.11 which was in the medium category. The results of inferential analysis on testing significant data using SPSS found that there was an influence of numeracy literacy on the mathematical communication skills of Class V students of SD Negeri 0507 Latong, Lubuk Barumun District, Padang Lawas Regency
Implementasi Aplikasi Exambro Sebagai Pengawasan Penilaian Hasil Belajar Peserta Didik di SMA Negeri 1 Wangon
Authors: Gunawan Yosi Intan Pandini
Published: October 2023

This research illustrates how the internet has provided unlimited access to vast educational and information resources. Educators and Learners can access learning materials, scientific journals, textbooks, and other online resources relevant to the learning topic. This eliminates geographical limitations and allows schools with limited resources to acquire quality learning materials. This study aims to determine the implementation of the exambro application as a supervision of the assessment of student learning outcomes at SMA Negeri 1 Wangon. Through the Exambro Application implemented at Wangon State High School, it can be an application to supervise students in the process of assessing learning outcomes. The type of research used is qualitative descriptive. The instruments used are observation and interviews. The results showed that this Exambro application can minimize cheating on students. The use of the Exambro application has advantages, but there are still disadvantages in the process of using it. That way educators must carefully prepare this application before sharing it with students. To create good internet utilization through this exambro application in supervising the assessment of student learning outcomes at Wangon State High School
Analisis Kesulitan Pembelajaran Berdiferensiasi pada Materi Bagian Tubuh Tumbuhan di Sekolah Dasar
Authors: Fitriah Iin , Widiyono Aan
Published: October 2023

This research aims to determine differentiated learning difficulties among primary school students. This condition is caused by teachers and students having difficulty implementing differentiated learning. This research design uses qualitative research. The research subjects were 24 students of class IV of SDN 3 Menganti. Data collection uses observation and interviews. Data analysis uses data reduction, data presentation and conclusion. Test data validity using technical triangulation and source triangulation. The results of this research show that teachers find it difficult to bring together the abilities and learning styles of each student and that the time, facilities and materials that teachers need to prepare are limited. The problems are also found among the students themselves, particularly due to internal and external factors. By preparing learning plans, developing learning strategies, learning materials, and performing cognitive diagnostic assessments that aim to maximize time allocation during the learning process
Analisis Kemampuan Mendidik Guru dalam Perkembangan Psikologi Anak di MIN 2 Palembang
Authors: Astuti Mardiah , Mutyati Mutyati , Septiani Tria , Nurfadillah Maja , Rahmawati Aliyah , Cantika Chania Mega , Ibrahim Ibrahim
Published: October 2023

The way teachers educate children in educational institutions is of utmost importance as it involves the psychological development of children. Teachers also have the responsibility to meet the needs of students, including their spiritual, intellectual, moral, ethical, and physical needs. This research examines how teachers educate children in their psychological development, conducted at MIN 2 Palembang. This study is field research with a qualitative descriptive approach. Data collection methods used were through interviews and observations. The data analysis technique includes data reduction, data presentation, and verification of research data results. The research results show that the way teachers educate children is crucial for the psychological development of students because a teacher's role is not only to impart knowledge but also to instill good morals in students. This way, students will hopefully be good both physically and mentally. The teaching methods of teachers in the psychological development of children at MIN 2 Palembang have been implemented. The teacher's approach to child development is crucial in helping children grow and develop optimally. Here are some steps and principles that can help teachers in dealing with the psychological development of children, including understanding the stages of child development, creating a safe and supportive learning environment, understanding the diversity of students, implementing active learning approaches, and involving all stakeholders, and fostering collaboration between parents, students, and educational institutions
Review Article: Analysis Caffeine in Powder Coffee Using Spectrophotometry UV-VIS Method
Authors: Abriyani Ermi , Nusaiba Amara Aisha , Wulandari Amalia , Setiawati Devi
Published: October 2023

Introduction: Caffeine is made by extraction from roasted and ground coffee by dichloromethane after being heated in deionized water mixed with magnesium oxide. The extract was purified, dried and bottled in a bottle of dark glass. A stratified random selection was applied to select a number of vials for the study of homogeneity and stability, which revealed that the prepared reference material was homogeneous and fairly stable.  Objective: This study aims to determine the level of caffeine levels in ground coffee.  The quantification of the % purity of caffeine was performed using a calibrated UV/visible UV/visible spectrophotometer and high-performance liquid chromatography calibrated by the diode-array detection method. Method: This study uses literature review, from several articles published in literature through PubMed, Science Direct,  Researchgate, publons and Google Scholar with articles published from 2012 to 2022.  Result and Discussion: The results obtained from both methods combined to drive the certified value and uncertainty regarding the certified value of the purity of the reference material were found to be 99.86% and the associated uncertainty was ±0.65%, which makes the candidate reference material a very useful calibran in the chemical analysis of food and medicine.  Conclusion: It can be concluded that the caffeine levels contained in robusta and arabica coffee beans with varying soaking duration of 3 days, 5 days, and 7 days there are differences in caffeine levels
ChatGPT and academic integrity in nursing and health sciences education
Authors: Alkhaqani Ahmed
Published: October 2023

As the realm of technology continues to evolve, artificial intelligence (AI) applications are revolutionizing various industries, including education. In the field of health sciences and nursing education, AI-powered tools such as ChatGPT are being utilized to enhance learning experiences and help students improve their academic performance. However, as with any technological advancement, there are certain concerns surrounding the use of AI in higher education. One of the main issues is the potential for plagiarism facilitated by AI. This article explores the role of AI and ChatGPT in health sciences and nursing education and the challenges it poses regarding academic integrity
Social Stigma and Psychological Burden among Caregivers of Children with Cerebral Palsy
Authors: Hassan Noora
Published: October 2023

The goal of the study was to assess the psychological burden and social stigma among caregivers of children with cerebral palsy. Find out the relationship between the psychological burden of parents' and their socio-demographic characteristics (Age, numbers of family members, marital status, level of education, occupation, participation in trainings about CP, monthly income of the family, residency area, and house ownership).
Material and methods: A descriptive design, a non-probability purposive sample of 80 parents having children with cerebral palsy was conducted in the period from March to July 2023. Setting of the Study: The study has been carried out on parents of children with cerebral palsy at the Physiotherapy Center and Oncology Center located in Al-Saddar Medical City.
Study's findings: The findings of the study revealed that the majority of caregivers were mothers. Most of the sample is their age (30–34), they graduated from secondary school, and suffer from insufficient monthly income. The majority of participants had a moderate level of psychological burden and social stigma, and we found a highly significant correlation between psychosocial burden and social stigma.
The study recommended providing access to counseling and mental health services to help parents manage their psychological burden and improve their mental health. Increasing awareness and education about cerebral palsy and its impact on families will reduce social stigma and improve the acceptance of children with cerebral palsy. Offering support groups for caregivers to connect and share their experiences.
Alchornea laxiflora as therapeutic agent in the treatment of Trypanosoma brucei brucei infection using experimental wistar rats; invivo and gene expression studies
Authors: Durojaye Catherine , Elekofehinti Olusola , Osho Innocent , Abodunrin Stephen
Published: October 2023

Aims: African trypanosomosis is a zoonotic tropical disease of Sub-Saharan Africa. Its etiology is a group of extracellular protozoans of the genera Trypanosoma which has numerous species including Trypanosoma brucei brucei. Inavailability of vaccines and numerous side effects arising from few available antitrypanosomal drugs gives the indication for search for local alternatives. This experimental study investigates the antitrypanosomal efficacy of chloroform extract of A. laxiflora leaves in wistar albino rats infected with Trypanosoma brucei brucei.

Place and Duration of Study: Animal Parasitology and Microbiology Research Unit, Department of Animal Production and Health, Federal University of Technology, Akure, Nigeria, between July and November, 2022.

Methodology: Thirty-six rats of both sexes were infected with Trypanosoma brucei brucei and treated with Alchornea laxiflora extracts intraperitoneally at dosages of 100, 200 and 400mg/kg for three consecutive days. Diminacene aceturate at 3.5mg/kg as single dose was used as positive control. Daily parasiteamia, rectal temperature and body weight were monitored for 26 days. Antioxidant (SOD, CAT, Nrf2) and pro-inflammatory (TNF-α, IL-6) gene expressions were determined.

Results: Treatment with Alchornea laxiflora caused significant (p < 0.05) decrease in parasitemia of infected rats compared to negative control. Increase in weight gain was recorded after the initial weight loss post infection. There was prolongation of survival days to 22days at 400mg/kg treatment dose compared to 7days in the untreated control. Significant (p < 0.05) dose dependent upward regulation of SOD, CAT and Nrf2 antioxidant genes and down-regulation of TNF-α and IL-6 inflammatory genes were observed in all treatment groups compared to the untreated control in the spleen and liver.

Conclusion: These observations suggest that A. laxiflora extract possess excellent anti-trypanosomal properties with the downregulation of pro inflammatory genes and up-regulation of antioxidant genes
Efficacy of different live infectious bursal disease vaccines on antibodies to infectious bursal disease virus and Newcastle disease vaccine La Sota in ISA brown chicks
Authors: Barka Sanni , Orakpoghenor Ochuko , Andamin Aliyu , Markus Talatu , Abdu Paul , Oladele Sunday , Wakawa Aliyu , Akade Felix , Madugu Shuaibu , Adam Mohammed
Published: October 2023

Aim: In this study, the efficacy of five commercial live infectious bursal disease (IBD) vaccines on antibody (Ab) decay and response to a very virulent IBD virus (vvIBDV) and Newcastle disease (ND) vaccine La Sota in ISA Brown chicks were assessed.
Methods: Seven groups of chickens (A, B, C, D, E, F, and G) comprising 50 chicks each were used for the study. Groups A, B, C, D, and E were vaccinated with Bur-706, MB-Strain, B87-Strain, Bursa-B2K, and HIPRA live IBD vaccines, respectively, at 14 and 28 days of age (doa), and challenged with a vvIBDV at 35 doa. Groups F and G served as positive and negative controls, respectively. At 42 doa, all groups were vaccinated with ND vaccine La Sota. Blood was collected at 1, 7, 14, 21, 28, 35, 42, and 49 doa, and serum was harvested. The serum was analyzed for IBD virus (IBDV) Ab titres using enzyme-linked immunosorbent assay (ELISA) and ND Ab titres using a haemagglutination inhibition (HI) test.
Results: Results revealed significantly (p < 0.05) higher ELISA IBDV Ab titres in groups A to E than in F from 21 to 49 doa, with the highest in group D. At 49 doa, there was significantly (p < 0.05) higher HI Ab titre in groups A to E than in F with the highest in group D. In conclusion, the live IBDV vaccines were immunogenic following vaccination. The vaccines decreased the decay of IBDV Ab and mitigated the decreased response to ND vaccine La Sota in the chicks following the vvIBDV challenge, with more effects induced by Bursa-B2K.
Conclusion: The live vaccines (Bur-706, MB-Strain, B87-Strain, Bursa-B2K, and HIPRA) were immunogenic following vaccination.
Meningkatkan Literasi Teknologi di Masyarakat Pedesaan Melalui Pelatihan Digital
Authors: Hariyanto  , Susanti Pipit Aprilia , Hadjaat Michael , Wasil Muhammad , Susilawati Agnes Dwita
Published: October 2023

Kehadiran teknologi menyebabkan meningkatnya kemakmuran bagi masyarakat. Namun sayangnya manfaat teknologi sering kali masih belum dapat dirasakan oleh masyarakat perdesaan secara maksimal. Hal ini dikarenakan masih rendahnya literasi teknologi di kalangan masyarakat perdesaan. Penelitian ini kemudian bertujuan untuk melihat mengenai bagaimana manfaat pelatihan digital di dalam masyarakat perdesaan dalam meningkatkan literasi teknologi. Proses pengabdian ini dapat dilaksanakan melalui ceramah dan praktik secara langsung. Dalam implementasinya, diperlukan adanya persiapan yang dapat dibagi sesuai tahapan-tahapan yang diperlukan. Hasil pengabdian ini mengharapkan untuk terjadinya adanya peningkatan di dalam pemahaman literasi teknologi bagi masyarakat perdesaan. Dengan peningkatan pemahaman ini, maka masyarakat perdesaan dapat merasakan manfaat dari kehadiran teknologi secara total. Dengan demikian, maka masyarakat desa dapat meningkatkan kelebihan produk lokal mereka, serta terhindar dari hoaks yang sering muncul di ranah digital. Hasil akhir yang diinginkan adalah masyarakat desa dapat merasakan kemakmuran sebagai akibat dari kehadiran teknologi digital.
The Challenges and Strategies of Social Workers in the Care of the Elderly with Chronic Illness
Authors: Tukino
Published: October 2023

The objective of the research is to identify, analyse, and understand the challenges faced by social workers in the care of older persons suffering from chronic diseases, as well as to describe and strategies used in addressing them. The research method uses a qualitative approach by conducting in-depth interviews with four social workers who have experience treating elderly people suffering from chronic diseases. The techniques used are interviews and observations, which are then analyzed using content analysis techniques. Research results show that social workers face several significant challenges in the care of older persons with chronic diseases, including the medical complexity of chronic disease, social isolation, mobility constraints, and financial problems. In addition, social workers also face obstacles in coordinating with various health and care services. However, it also developed various effective strategies, such as collaborative approaches with multidisciplinary care teams, intensive emotional support, and providing education to patients and their families. The results of the research can conclude that social workers have an important role to play in addressing the complex challenges in the care of older people with chronic diseases. The strategy applied can help improve the quality of life of patients and support their families in the face of emerging problems.
Nursing Care Of Type Ii Diabetes Mellitus Patients
Authors: Yestika Saleha Triya , Cahyati Yanti , Arifin Hidayat Unang
Published: October 2023

Background: Type II Diabetes Mellitus is a chronic disease with a high prevalence in Indonesia. As nursing care providers, nurses have an essential role in managing patients with type II Diabetes Mellitus. Purpose: Get an overview of the implementation of nursing care in patients with Type II Diabetes Mellitus. Methodology: A case study was conducted on Mrs. D in Dahlia Room  RSUD Ciamis  on 27 - 30 June 2022. Results: The results of the nursing evaluation obtained: ineffective peripheral perfusion, acute pain, nutritional deficits, impaired skin integrity, unstable blood glucose levels, impaired physical mobility, and disturbed sleep patterns are partially resolved, and the risk of hypovolemia has been determined. Conclusion: Nursing care carried out can overcome the problems experienced by patients.
Application Of Five Finger Hypnosis To Anxiety In Hypertension Patients In The Cikoneng Health Center Kabupaten Ciamis
Authors: Asep Riyana  , Rahmat Salsabila
Published: October 2023

The high mortality due to hypertension and various possible complications due to hypertension can make people with hypertension not only have physiological but also psychological diseases such as anxiety. Hypertension sufferers who experience anxiety will show mental symptoms in the body such as stuttering, panic, fear. Mental symptoms in other anxiety vary, such as dizziness or lightheadedness, difficulty breathing, lack of fluids, excess watery bowel movements, heart palpitations. The prevalence of hypertension varies greatly in each region. Based on data taken regarding the summary of reports of the 10 most common diseases at the UPTD Cikoneng Health Center in 2021, hypertension is in third place with a total of 656 people. The purpose of this study was to describe the application of five finger hypnosis to people with anxiety. The process of providing nursing care was carried out for three days, starting from April 4 to April 9 2022. The problem experienced by the client was the level of anxiety and hypertension experienced by Mrs.E and Mrs.Y. the conclusion that there is an influence in the application of five finger hypnosis therapy on anxiety in hypertensive patients.
Фермерські господарства в Україні: стан та перспективи розвитку
Authors: Беженар І. М. , Грищенко О. Ю.
Published: October 2023

Фермерство в Україні не просто економічна галузь, але й справжня історія підприємницького духу та самостійності, яка відзначається інноваціями та прагненням до якісного та сталого розвитку аграрного сектору. Тому важливим є визначення шляхів для подальшого розвитку цього сектору. Основною метою статті є аналіз сучасного стану розвитку фермерських господарств в Україні, виявлення ключових проблем, які впливають на їхню діяльність і визначення пріоритетних напрямків, потенціалу та можливостей, фермерських господарств у контексті глобальних викликів та пошук шляхів їх сталого розвитку. У результаті вивчення цієї проблеми були виявлені нові можливості, спрямовані на підвищення ефективності фермерських господарств та підтримку їхнього розвитку – орієнтація на виробництво нішевої продукції, органічної тощо. Визначена їх важлива роль у сільському господарстві для забезпечення продовольчої безпеки та стійкості сільськогосподарського сектору в цілому. Досліджено ключові обмежуючі фактори, які гальмують їхній потенційний розвиток, та окреслено шляхи їхнього стимулювання через надання вигідних іпотечних кредитів та інших засобів держпідтримки на конкретні цілі. Практична значущість результатів даного дослідження полягає у можливості використання отриманих висновків для оцінки ефективності різних методів та механізмів впливу на розвиток фермерських господарств в Україні.
Місія та етимологія аудиту оподаткування великих підприємств
Authors: Татенко Н. Ю. , Назарова К. О.
Published: October 2023

У статті досліджено місію та етимологію аудиту оподаткування для великих підприємств. Проаналізовано його нормативно-правове регулювання в Україні та країнах ЄС. Обґрунтовано місію аудиту оподаткування як інструменту протидії шахрайству та корупції на підприємстві. Досліджено динаміку збиткових великих підприємств та зареєстрованих кримінальних правопорушень у сфері оподаткування. Надано оцінку звітів податкових органів за 2020 – 2022 роки наведено суми донарахування податків внаслідок порушення чинного законодавства. Наведені результати компаративного аналізу різного трактування законодавства між підприємствами і податковими органами (які виникають суперечки, їх результати тощо). Обґрунтовано місію аудиту у стимулюванні платників до сплати всіх податків та достовірному їх декларуванні. Наведено професійно обґрунтоване визначення поняття «аудит оподаткування» та обґрунтовано зміни, які необхідно внести в чинне законодавство для гармонізації співвідношення понять «аудит», «аудит оподаткування» та «податковий аудит».
CLASSIFICATION OF FORMS OF COMMITTING A THREAT OF MURDER OR CAUSING SERIOUS HARM TO HEALTH, IN RELATION TO ARTICLE 119 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION
Authors: Шутова Ю.А.
Published: October 2023

В статье представлен анализ возможных форм совершения угрозы убийством или причинением тяжкого вреда здоровью, а также систематизация и клас-сификация выявленных форм. Материалы и методы. В ходе исследования использовались мнения отече-ственных ученых, судебно-следственная практика в виде 170 материалов уголовных дел и 200 судебных решений (обвинительные приговоры и постановления об освобож-дении лица от уголовной ответственности в связи с примирением сторон) по ст.119 УК РФ, а также экспертная оценка 100 сотрудников правоохранительных органов. Автор использовал общенаучные методы: системный подход, индукция, аналогия, анализ, синтез, социологический опрос в форме анкетирования. Результаты исследования. В работе произведена классификация форм выраже-ния угрозы убийством или причинением тяжкого вреда здоровью по степени структу-рированности, применительно к ст.119 УК РФ. Выводы и заключения. Разработанная классификация позволит правопримени-телям правильно толковать диспозицию ч.1 ст.119 УК РФ, в следствии чего планиру-ется повышение эффективности защиты личности от преступных посягательств на пси-хическое и социальное здоровье.

The article presents an analysis of possible forms of committing a threat of murder or causing serious harm to health, as well as systematization and classification of the identified forms. Materials and Methods: the research used the opinions of domestic scientists, foren-sic investigative practice in the form of 170 materials of criminal cases and 200 convictions under Article 119 of the Criminal Code of the Russian Federation, as well as an expert as-sessment of 100 law enforcement officers. The author used general scientific methods: a sys-tematic approach, induction, analogy, analysis, synthesis, a sociological survey in the form of a questionnaire. The Results of the study: the paper classifies the forms of expression of the threat of murder or causing serious harm to health according to the degree of structuring, in relation to Article 119 of the Criminal Code of the Russian Federation. Findings and Conclusions: the developed classification will allow law enforcement officers to correctly interpret the disposition of Part 1 of Article 119 of the Criminal Code of the Russian Federation, as a result of which it is planned to increase the effectiveness of pro-tecting the individual from criminal attacks on mental and social health.