bluuebunny/crossref_metadata_2025 huggingface dataset:
SHEEP PRODUCTION ON DRYLAND LUCERNE
Authors: Knight T.L.
Published: July 2020

On dryland at Winchmore Irrigation Research Station in Mid Canterbury high levels of lamb production were obtained during 12 years in a self-contained lucerne/supplementary forage farmlet. The system established lucerne under a barley crop and used turnips with Italian ryegrass and Tama ryegrass in the lucerne renewal rotation. Lucerne hay and barley grain and straw were conserved for supplementary feed. Stocked at 15 ewes/ha, lamb meat production varied from 210-300 kg/ha between years. This variation reflected the effect of dry summer conditions on both lucerne growth and the establishment of the supplementary crops which in turn influenced ewe prolificacy and lamb growth. Because of yield variability and increasing costs, use of annual forage crops in a dryland sheep unit is questioned. Keywords: grazing, management, forage crops, lamb production
FAKTOR- FAKTOR YANG MEMPENGARUHI CASH HOLDING
Authors: Astuti Nita , Ristiyana Rida , Nuraini Luthfi
Published: July 2020

Penelitian ini bertujuan untuk mengetahui pengaruh siklus konversi kas, pertumbuhan penjualan, ukuran perusahaan  dan modal kerja bersih terhadap kas ditangan pada perusahaan manufaktur yang terdaftar di bursa efek indonesia periode 2017-2019. Metode pemilihan sampel menggunakan purposive sampling, sehingga diperoleh 97 perusahaan dengan data pengamatan (n) = 264 dengan analisis data menggunakan regresi linier berganda. Berdasarkan hasil analisis disimpulkan bahwa secara parsial variabel siklus konversi kas dan modal kerja bersih berpengaruh signifikan terhadap kas ditangan,  sedangkan variabel pertumbuhan penjualan dan ukuran perusahaan tidak berpengaruh signifikan terhadap kas ditangan. Secara simultan siklus konversi kas, pertumbuhan penjualan, ukuran perusahaan dan modal kerja bersih berpengaruh terhadap kas ditangan. Kata kunci: Kas ditangan, Siklus Konversi Kas, Pertumbuhan Penjualan, Ukuran Perusahaan Modal Kerja Bersih
Іпостась генерала О.О. Загродського (за матеріалами мемуарної літератури)
Authors: Rohozha Maria
Published: July 2020

Генерал Армії УНР О.О. Загродський у період національно-визвольних змагань 1917-1921 рр. виявив себе професійним військовим. Отримав належне сімейне виховання та визначивши особисті пріоритети у житті, він вибрав військову службу, розпочав її рядовим солдатом. До жовтневого перевороту 1917 р. устиг взяти учать у боях Першої світової війни, отримати досвід керівництва військовими підрозділами та чин штабс-капітана. У непростому політичному житті 1917 р. прийняв свідоме рішення, перейшов на службу до українського війська. Подальша участь у збройній боротьбі за українську державність остаточно сформувала його іпостась вояка.
«Зруйнований мікрокосмос»: сім’я парафіяльного священника в радянській Україні у 1920-1930-х рр.
Authors: Savchuk Tetiana
Published: July 2020

У статті здійснена спроба мікроісторичного аналізу становища сім’ї парафіяльного сільського священника з Дніпропетровщини Сергія Андрійовича Мізецького в умовах суспільно-політичних трансформацій у радянській Україні в 1920-1930-х рр. Простежено моделі взаємодії між представниками різних поколінь, ступінь впливу радянської модернізації на формування членами сім’ї стратегій побудови життєвої траєкторії. Показано, що відмова від власного «я», свого минулого у родині священника мала поступовий, трагічний і незворотний характер.
Формування першої в УСРР школи конструкторів електричних машин (1920-і роки)
Authors: Annienkov Ihor
Published: July 2020

У статті встановлено, що форматом першої в УСРР школи конструкторів електричних машин стало відкрите у 1930 р. Відділення електромашинобудування вищого технічного навчального закладу при Харківському електромеханічному заводі. Її остаточне формування в Харкові, попри наявний на момент встановлення радянської влади в Україні потенціал щодо створення таких шкіл у низці її регіонів, зумовлювалося провадженою урядом СРСР протягом 1920-х років промисловою політикою. Першість організації школи конструкторів електричних машин саме на промисловому підприємстві стала об’єктивним наслідком обраного способу наукового забезпечення вітчизняного електромашинобудівного виробництва.
PENGARUH PERAN KELUARGA, AKTIVITAS FISIK, INTERAKSI SOSIAL DAN STRES TERHADAP KUALITAS HIDUP LANSIA
Authors: Savita Riza
Published: July 2020

Kualitas hidup merupakan suatu konsep yang luas terdiri dari kesehatan fisik, psikologis, hubungan sosial dan hubungan dengan lingkungan. Masa lansia akan mengalami suatu perubahan dalam segi fisik, kognitif maupun dalam kehidupan psikososialnya sehingga dapat mempengaruhi kualitas hidup lansia tersebut. Tujuan penelitian ini adalah untuk mengetahui pengaruh langsung dan tidak langsung serta besaran antara peran keluarga, aktivitas fisik, interaksi sosial, dan stres terhadap kualitas hidup lansia di Puskesmas Petaling Mendobarat Bangka Belitung tahun 2017. Metode penelitian ini adalah pendekatan kuantitatif dengan desain cross-sectional. Jumlah sampel 60 lansia. Metode analisis dengan Structural Equation Model (SEM) mengunakan SmartPLS 2.0. Hasil pengujian hipotesis SEM dengan metode SmartPLS menghasilkan temuan penelitian yaitu peran keluarga (2,14%), aktivitas fisik (13,01%), interaksi sosial (57,41%) dan stres (13,34%). Pengaruh langsung kualitas hidup lansia di Puskesmas Petaling Mendobarat Bangka Belitung sebesar 85,90% dan pengaruh tidak langsung sebesar 6,27%. Total pengaruh langsung dan tidak langsung kualitas hidup lansia sebesar 92,17%. Semakin tinggi interaksi sosial lansia maka semakin baik kualitas hidup lansia dan sebaliknya semakin rendah interaksi sosial lansia maka semakin buruk kualitas hidup lansia. Saran penelitian adalah Puskesmas sebaiknya meningkatkan program posyandu lansia dan lebih mengoptimalkan senam lansia yang sudah ada sehingga para lansia mampu lebih berinteraksi kepada sesama lansia, petugas kesehatan dan kader.
Efek Pemberian Jus Semangka Terhadap Penurunan Tekanan Darah
Authors: Munir Zainal , Muhajaroh Muhajaroh
Published: July 2020

Hipertensi adalah penyakit degeneratif  yang semakin sering dijumpai dimasyarakat. Hipertensi juga mempunyai hubungan erat dengan resiko kejadian penyakit kardiovaskuler, dengan tekanan darah yang lebih tinggi, maka akan lebih besar pula kemungkinan terjadinya penyakit ginjal, stroke, serangan jantung, dan gagal jantung. Tujuan penelitian adalah Menganalisa adanya pengaruh pemberian jus semangka terhadap perubahan tekanan darah sistolik dan diastolik pada penderita hipertensi di Dusun Tanjung Lor Desa Karang Anyar Paiton Probolinggo. Desain dalam penelitian ini menggunakan eksperimen semu (quasy experiment design), dengan perancangan pretest-posttest with control group. Teknik yang digunakan ialah teknik purposive sampling dengan jumlah  populasi 35 individu yang mengalami hipertensi dan sampel yang digunakan adalah 30 individu sebagai responden dengan penyakit hipertensi, Penelitian ini dilakukan 10 hari dan responden diukur tekanan darahnya pre dan post intervensi, observasi tekanan darah selama 3 hari dengan pre perlakuan. 7 hari dengan perlakuan waktu pengukuran 2 jam setelah perlakuan, penelitian ini dilakukan untuk mengetahui perbedaan tekanan darah sistolik dan diastolik pre perlakuan dengan setelah perlakuan. Hasil uji analisa statistik menunjukkan ada pengaruh pemberian jus semangka terhadap penurunan tekanan darah sistolik dan diastolik dengan p=<0.05 (0.010). Kesimpulan dari penelitian ini adalah ada perbedaan tekanan darah pada penderita hipertensi setelah pemberian jus semangka terhadap penurunan tekanan darah sistolik dan diastolik. Berdasarkan hasil penelitian ini diharapkan memberikan manfaat bagi masyarakat dan merupakan salah satu solusi bagi perawatan penderita hipertensi.
Persepsi Perawat Tentang Spiritual Care di Ruang Intensive Care Unit
Authors: Maryana Maryana , Erwan Erwan
Published: July 2020

Spiritual care merupakan hal yang penting bagi pasien. Satu – satunya sumber penyembuhan (healing) bagi pasien terminal adalah spiritualitas mereka. Namun dalam pelayanan keperawatan masih terfokus pada aspek fisik. Tujuan penelitian ini adalah untuk mengeksplorasi persepsi perawat tentang spiritual care di ruang Intensive Care Unit (ICU) Rumah Sakit Medika Stannia Sungailiat.Jenis penelitian kualitatif dengan pendekatan fenomonologi. Informan 10 orang dengan teknik non purposive sampling. Tehnik pengumpulan data, wawancara dan observasi. Terdapat 5 tema persepsi perawat tentang spiritual care, yaitu pemahaman perawat tentang spiritual care, cara perawat mengidentifikasi kebutuhan spiritual pasien, pelaksanaan spiritual care, berbagai hambatan dalam pelaksanaan spiritual care, dan harapan terhadap spiritual care : advokasi dalam pembuatan kebijakan di rumah sakit tentang kewajiban perawat melaksanakan spiritual care, upaya bimbingan dalam peningkatan pengetahuan, serta evaluasi berkelanjutan dalam melaksanakan spiritual care di ruangan.
Faktor-Faktor yang Berhubungan dengan Kunjungan Antenatal Care Ibu Hamil di Puskesmas
Authors: Anggriani Gustika
Published: July 2020

Peningkatan KPS Ibu di Indonesia yang melakukan pemeriksaan kehamilan dari 95,2% menjadi 96,1%, proporsi k1 ideal dari 81,3% menjadi 86%, proporsi pemeriksaan kehamilan (k4) dari 70% menjadi 74,1% sedangkan proporsi persalinan di fasilitas kesehatan dari 66,7% menjadi 79,3% (Riskesdas 2013). Tujuan penelitian adalah mengetahui yang berhubungan dengan kunjungan ANC di puskesmas pasar kota prabumulih tahun 2019. Penelitian ini menggunakan Survey Analitik dengan menggunakan pendekatan Cross Sectional. Populasi penelitian ini adalah keseluruhan ibu hamil dengan usia kehamilan trimester III yang berjumlah 54 orang. Sampel berjumlah 54 responden. Pada analisa univariat didapatkan responden yang usia beresiko 33 responden (61,1%) dan responden yang usia tidak beresiko sebanyak 21 responden (38,9%). Paritas risiko tinggi sebanyak 35 responden (64,8%) dan paritas risiko rendah sebanyak 19 responden (35,2%). Berpendidikan tinggi sebanyak 41 responden (75,9%) dan rendah sebanyak 13 responden (24,1%). Berpengetahuan baik sebanyak 43 responden (79,6%) dan kurang baik sebanyak 11 responden (20,4%). Analisa Bivariat menunjukkan Usia Ibu mempunyai hubungan yang bermakna dengan kunjungan antenatal care (p value 0,002), Paritas Ibu mempunyai hubungan yang bermakna dengan kunjungan antenatal care (p value 0,000), Pendidikan Ibu mempunyai hubungan yang bermakna dengan kunjungan antenatal care (p value 0,000) dan Pengetahuan Ibu mempunyai hubungan yang bermakna dengan kunjungan antenatal care (p value 0,000). Simpulan dari penelitian ini adalah bahwa ada faktor-faktor yang berhubungan dengan kunjungan antenatal care di puskesmas.
Pengukuran Faktor yang Berpengaruh Terhadap Kualitas Hidup Penderita HIV/AIDS Pada Ibu Rumah Tangga
Authors: Patimah Siti
Published: July 2020

Kualitas hidup merupakan keadaan dimana seseorang mendapatkan kepuasan dan kenikmatan dalam kehidupan sehari-hari. Kualitas hidup tersebut menyangkut kesehatan fisik dan kesehatan mental yang berarti jika seseorang sehat secara fisik dan mental maka orang tersebut akan mencapai kepuasan dalam hidupnya.Tujuan dari penelitian ini untuk mengetahui pengaruh langsung dan tidak langsung promosi kesehatan lingkungan sosial, peran petugas kesehatan dan peran suami terhadap kualitas hidup penderita HIV/AIDS pada ibu rumah tangga di Yayasan Pelita Ilmu tahun 2017. Penelitian ini menggunakan metode cross sectional dengan sampel sebanyak 70 responden. Metode analisis yang digunakan adalah Structural Equation Model (SEM) menggunakan Smart PLS2.0 dan SPSS 18. Hasil penelitian ini menunjukkan pengaruh langsung dan tidak langsung antara variabel promosi kesehatan, lingkungan sosial, peran petugas kesehatan dan peran suami, terhadap kualitas hidup penderita HIV/AIDS pada ibu rumah tangga sebesar 76,8%. Variabel kualitas hidup dipengaruhi langsung oleh beberapa variabel, diantaranya promosi kesehatan (12,14%), lingkungan sosial (23,83%), peran petugas kesehatan (30,31%), dan peran suami sebesar (10,50%). Pengaruh tidak langsung sebesar 1,51%. Petugas kesehatan di Yayasan Pelita Ilmu sehingga lebih meningkatkan pelayanan pendidikan serta pendekatan kepada penderita HIV/AIDS sehingga akan meningkatkan kualitas hidup yang lebih baik.
COVID-19 PANDEMIC- ATTRIBUTES IN CHILDREN AND IMPLICATIONS FOR CLINICAL PAEDIATRIC DENTISTRY –A REVIEW ARTICLE.
Authors: BANERJEE AAHELI , GHOSH AINDRILA , ZAHIR SHABNAM , KUNDU GAUTAM
Published: July 2020

The pandemic spread of COVID -19 infection has gripped the entire world and caused public health concerns. The pathogen of this zoonotic infection is believed to be present in abundance in the nasopharynx and saliva of the affected patients and spreads through respiratory droplets. The dentists, including the paediatric dentists may come across suspected or confirmed infected patients and have to use their professional judgement not only in dealing with these patients but also to prevent nosocomial infections. This article aims to provide an overview of COVID- 19 disease, the characteristics of the infection in children, recommendations for paediatric dental practice and strategies to control the COVID-19 infections.

KEYWORDS- Corona virus, paediatric dentistry, immunology, infection control.
Glide Path: “Path to the successful root canal instrumentation”- Review
Authors: Mairal Oak Anjali
Published: July 2020

Appropriate biomechanical preparation of the root canal is the base for successful root canal treatment. The “mechanical” part of this procedure which is the root canal instrumentation is not complete without achieving “glide path”. Clinicians must understand the importance of this small and simple but important concept of glide path which in turn will help to avoid a number of mishaps and give a long term predictable endodontic success.

Key Words : “ Glide path, Rotary instrumentation “
UPAYA PENINGKATAN PENJARIGAN IBU HAMIL RESIKO TINGGI DENGAN METODE SKOR POEDJI ROCHYATI
Authors: Nilakesuma Nur Fadjri
Published: July 2020

Penyebab kematian ibu dan bayi dapat dicegah dengan melakukan pemeriksaan kehamilan  (antenatal care atau ANC) yang memadai dengan memberikan alat skrining Kartu Skor Poedji Rochjati (KSPR) oleh mitra kesehatan (kader) dan petugas kesehatan lainnya. Cakupan deteksi dini ibu hamil resiko tinggi di kelurahan Kurao Pagang Wilayah Kerja Puskesmas Nanggalo Padang paling rendah jika dibandingkan dengan 2 kelurahan lainnya yaitu hanya sebesar 7,8% .Hasil diskusi yang dilakukan tim pengabdi terhadap mitra didapatkan rendahnya capaian ini dikarenakan keterbatasan pengetahuan masyarakat dan kemampuan kader dalam melakukan deteksi dini ibu hamil resiko di lingkungan. Metode pengabdian adalah melakukan penjaringan ibu hamil resiko, penyuluhan kesehatan dengan teknik focus grup diskusi dan simulasi pengisian kartu skor poedji rochyati oleh kader. Hasil pengabdian adalah Lebih dari separoh (60%) ibu hamil terkategori kehamilan resiko tinggi dengan jumlah skor 6. Terdapat peningkatan kemampuan mitra kesehatan dalam menggunakan kartu skor poedji rochyati ketika tim pengabdi memberikan contoh kasus sebesar 80%.  Deteksi dini (skrinning) sedini mungkin terhadap kehamilan risiko tinggi pada awal kehamilan dapat dilakukan oleh ibu hamil, keluarga dan kader kesehatan untuk mencegah kematian ibu dan bayi
Hydrogel Nanoparticle as a Functional Coating Layer in Biosensing, Tissue Engineering, and Drug Delivery
Authors: Cho Heejoo , Jeon Sumin , Yang Junghyeok , Baek Song Yi , Kim Doeun
Published: July 2020

The development of functional coating materials has resulted in many breakthroughs in the discovery of energy, environmental, and biomedical applications. Responsive polymeric hydrogels are an example of smart coating materials due to their stimuli-responsive characteristics upon changes in their local environment. This review focuses on the introduction of hydrogel nanoparticles and their applications in functional layers as responsive coating materials. Hydrogels are explained by the composition of cross-links and monomers used for preparation. In particular, an important class of responsive hydrogels, that is, nanosized hydrogel particles (nanogels), are described for thee synthesis, modification, and application in assembly of functional coating layers. Finally, nanogel functional layers for biological applications will be discussed with recent advances in biosensing, tissue engineering, and drug delivery.
Synthetic Mono-Rhamnolipids Display Direct Antifungal Effects and Trigger an Innate Immune Response in Tomato against Botrytis Cinerea
Authors: Robineau Mathilde , Le Guenic Sarah , Sanchez Lisa , Chaveriat Ludovic , Lequart Vincent , Joly Nicolas , Calonne Maryline , Jacquard Cédric , Declerck Stéphane , Martin Patrick , Dorey Stephan , Ait Barka Essaid
Published: July 2020

Natural rhamnolipids are potential biocontrol agents for plant protection against bacterial and fungal diseases. In this work, we synthetized new synthetic mono-rhamnolipids (smRLs) consisting in a rhamnose connected to a simple acyl chain and differing by the nature of the link and the length of the lipid tail. We then investigated the effects of these ether, ester, carbamate or succinate smRL derivatives on Botrytis cinerea development, symptoms spreading on tomato leaves and immune responses in tomato plants. Our results demonstrate that synthetic smRLs are able to trigger early and late immunity-related plant defense responses in tomato and increase plant resistance against B. cinerea in controlled conditions. Structure-function analysis showed that chain length of the lipidic part and type of acyl chain were critical to smRLs immune activity and to the extent of symptoms caused by the fungus on tomato leaves.
Interaction of Ampicillin and Amoxicillin with Mn2+: A Speciation Study in Aqueous Solution
Authors: Foti Claudia , Giuffrè Ottavia
Published: July 2020

A potentiometric and UV spectrophotometric investigation on Mn2+-ampicillin and Mn2+-amoxicillin systems in NaCl aqueous solution is reported. The potentiometric measurements were carried out under different conditions of temperature (15 ≤ t/°C ≤ 37). The obtained speciation pattern includes two species for both the investigated systems. More in detail, for system containing ampicillin MLH and ML species, for that containing amoxicillin, MLH2 and MLH ones. The spectrophotometric findings have fully confirmed the results obtained by potentiometry for both the systems, in terms of speciation models as well as the stability constants of the formed species. Enthalpy change values were calculated via the dependence of formation constants of the species on temperature. The sequestering ability of ampicillin and amoxicillin towards Mn2+ was also evaluated under different conditions of pH and temperature via pL0.5 empirical parameter (i.e., cologarithm of the ligand concentration required to sequester 50% of the metal ion present in traces).
Taste Processing: Insights from Animal Models
Authors: Molero-Chamizo Andrés , Rivera-Urbina Guadalupe Nathzidy
Published: July 2020

Taste processing is an adaptive mechanism involving complex physiological, motivational and cognitive processes. Animal models have provided relevant data about the neuroanatomical and neurobiological components of taste processing. From these models, two important domains of taste responses are described in this review. The first part focuses on the neuroanatomical and neurophysiological bases of olfactory and taste processing. The second part describes the biological and behavioral characteristics of taste learning, with an emphasis on conditioned taste aversion as a key process for the survival and health of many species, including humans.
Structure-Based Design of Biologically Active Compounds
Authors: Gemma Sandra
Published: July 2020

The past decades have witnessed tremendous progress in the detailed structural knowledge of proteins as potential or validated drug targets and the discovery of new drugs based on this wealth of knowledge progressed in parallel [...]
New Dihydroxytyrosyl Esters from Dicarboxylic Acids: Synthesis and Evaluation of the Antioxidant Activity In Vitro (ABTS) and in Cell-Cultures (DCF Assay)
Authors: Roma Elia , Mattoni Elena , Lupattelli Paolo , Moeini Seyed Sepehr , Gasperi Tecla , Bernini Roberta , Incerpi Sandra , Tofani Daniela
Published: July 2020

New dihydroxytyrosyl esters 2a, 2c–2j of dicarboxylic acids were synthesized from methyl orthoformate protected hydroxytyrosol 3 and diacyl chlorides. New compounds were characterized (HRMS, FT-IR, 1H- and 13C-NMR), and tested for antioxidant activity both in vitro (ABTS) and on L6 myoblasts and THP1 leukemic monocytes cell culture by DCF assay. According to the ABTS assay, compounds 2a, 2c–2j showed a TEAC value of antioxidant capacity up to twice that of Trolox. Very high or complete ROS protections were obtained in the cell environment where lipophilicity and rigidity of dicarboxylic structure seem to facilitate the antioxidant effect. MTT assay and proliferation test were used for assessment of cell viability. These compounds can be envisaged as a new class of preservatives for food or cosmetic products.
N-Heterocyclic Carbene Platinum(IV) as Metallodrug Candidates: Synthesis and 195Pt NMR Chemical Shift Trend
Authors: Bouché Mathilde , Vincent Bruno , Achard Thierry , Bellemin-Laponnaz Stéphane
Published: July 2020

A series of octahedral platinum(IV) complexes functionalized with both N-heterocyclic carbene (NHC) ligands were synthesized according to a straightforward procedure and characterized. The coordination sphere around the metal was varied, investigating the influence of the substituted NHC and the amine ligand in trans position to the NHC. The influence of those structural variations on the chemical shift of the platinum center were evaluated by 195Pt NMR. This spectroscopy provided more insights on the impact of the structural changes on the electronic density at the platinum center. Investigation of the in vitro cytotoxicities of representative complexes were carried on three cancer cell lines and showed IC50 values down to the low micromolar range that compare favorably with the benchmark cisplatin or their platinum(II) counterparts bearing NHC ligands.
Asymmetric Dinuclear Lanthanide(III) Complexes from the Use of a Ligand Derived from 2-Acetylpyridine and Picolinoylhydrazide: Synthetic, Structural and Magnetic Studies
Authors: Maniaki Diamantoula , Perlepe Panagiota S. , Pilichos Evangelos , Christodoulou Sotirios , Rouzières Mathieu , Dechambenoit Pierre , Clérac Rodolphe , Perlepes Spyros P.
Published: July 2020

A family of four Ln(III) complexes has been synthesized with the general formula [Ln2(NO3)4(L)2(S)] (Ln = Gd, Tb, Er, and S = H2O; 1, 2 and 4, respectively/Ln = Dy, S = MeOH, complex 3), where HL is the flexible ditopic ligand N’-(1-(pyridin-2-yl)ethylidene)pyridine-2-carbohydrazide. The structures of isostructural MeOH/H2O solvates of these complexes were determined by single-crystal X-ray diffraction. The two LnIII ions are doubly bridged by the deprotonated oxygen atoms of two “head-to-head” 2.21011 (Harris notation) L¯ ligands, forming a central, nearly rhombic {LnIII2(μ-OR)2}4+ core. Two bidentate chelating nitrato groups complete a sphenocoronal 10-coordination at one metal ion, while two bidentate chelating nitrato groups and one solvent molecule (H2O or MeOH) complete a spherical capped square antiprismatic 9-coordination at the other. The structures are critically compared with those of other, previously reported metal complexes of HL or L¯. The IR spectra of 1–4 are discussed in terms of the coordination modes of the organic and inorganic ligands involved. The f-f transitions in the solid-state (diffuse reflectance) spectra of the Tb(III), Dy(III), and Er(III) complexes have been fully assigned in the UV/Vis and near-IR regions. Magnetic susceptibility studies in the 1.85–300 K range reveal the presence of weak, intramolecular GdIII∙∙∙GdIII antiferromagnetic exchange interactions in 1 [J/kB = −0.020(6) K based on the spin Hamiltonian Ĥ = −2J(ŜGd1∙ ŜGd2)] and probably weak antiferromagnetic LnIII∙∙∙LnIII exchange interactions in 2–4. Ac susceptibility measurements in zero dc field do not show frequency dependent out-of-phase signals, and this experimental fact is discussed for 3 in terms of the magnetic anisotropy axis for each DyIII center and the oblate electron density of this metal ion. Complexes 3 and 4 are Single-Molecule Magnets (SMMs) and this behavior is optimally observed under external dc fields of 600 and 1000 Oe, respectively. The magnetization relaxation pathways are discussed and a satisfactory fit of the temperature and field dependencies of the relaxation time τ was achieved considering a model that employs Raman, direct, and Orbach relaxation mechanisms.
Vasodilatory Effect of Phellinus linteus Extract in Rat Mesenteric Arteries
Authors: Kwon Youngin , Haam Chae Eun , Byeon Seonhee , Choi Soo Jung , Shin Dong-Hoon , Choi Soo-Kyoung , Lee Young-Ho
Published: July 2020

Phellinus linteus is a well-known medicinal mushroom that is widely used in Asian countries. In several experimental models, Phellinus linteus extracts were reported to have various biological effects, including anti-inflammatory, anti-cancer, hepatoprotective, anti-diabetic, neuroprotective, and anti-angiogenic activity. In the present study, several bioactive compounds, including palmitic acid ethyl ester and linoleic acid, were identified in Phellinus linteus. The intermediate-conductance calcium-activated potassium channel (IKCa) plays an important role in the regulation of the vascular smooth muscle cells’ (VSMCs) contraction and relaxation. The activation of the IKCa channel causes the hyperpolarization and relaxation of VSMCs. To examine whether Phellinus linteus extract causes vasodilation in the mesenteric arteries of rats, we measured the isometric tension using a wire myograph. After the arteries were pre-contracted with U46619 (a thromboxane analogue, 1 µM), Phellinus linteus extract was administered. The Phellinus linteus extract induced vasodilation in a dose-dependent manner, which was independent of the endothelium. To further investigate the mechanism, we used the non-selective K+ channel blocker tetraethylammonium (TEA). TEA significantly abolished Phellinus linteus extract-induced vasodilation. Thus, we tested three different types of K+ channel blockers: iberiotoxin (BKca channel blocker), apamin (SKca channel blocker), and charybdotoxin (IKca channel blocker). Charybdotoxin significantly inhibited Phellinus linteus extract-induced relaxation, while there was no effect from apamin and iberiotoxin. Membrane potential was measured using the voltage-sensitive dye bis-(1,3-dibutylbarbituric acid)-trimethine oxonol (DiBAC4(3)) in the primary isolated vascular smooth muscle cells (VSMCs). We found that the Phellinus linteus extract induced hyperpolarization of VSMCs, which is associated with a reduced phosphorylation level of 20 KDa myosin light chain (MLC20).
10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells
Authors: Ediriweera Meran Keshawa , Moon Jeong Yong , Nguyen Yen Thi-Kim , Cho Somi Kim
Published: July 2020

10-Gingerol is a major phenolic lipid found in the rhizomes of ginger (Zingiber officinale). Being amphiphilic in nature, phenolic lipids have the ability to incorporate into cell membranes and modulate membrane properties. The purpose of the present study was to evaluate the effects of 10-gingerol on lipid raft/membrane raft modulation in radio-resistant triple negative breast cancer (MDA-MB-231/IR) cells. The effects of 10-gingerol on MDA-MB-231/IR cells’ proliferation, clonogenic growth, migration, and invasion were assayed using MTT, colony formation, cell migration, and invasion assays, respectively. Sucrose density gradient centrifugation was used to extract lipid rafts. Western blotting and immunofluorescence were employed to assess the effects of 10-gingerol on lipid raft/membrane raft modulation and lipid rafts-associated PI3K/Akt signaling. Cholesterol measurements were carried out using a commercially available kit. 10-gingerol suppressed the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. Moreover, 10-gingerol was found to modulate the lipid rafts of MDA-MB-231/IR cells and attenuate the key PI3K/Akt signaling components in lipid rafts. The cholesterol content of the lipid rafts and rafts-resident Akt signaling were also affected by exposure to 10-gingerol. The results of the present study highlight rafts-associated PI3K/Akt signaling as a new target of 10-gingerol in MDA-MB-231/IR cells, thus rationalizing a new rafts-mediated treatment approach for radio-resistant triple negative breast cancer cells.
The Relationships among Environments, External Knowledge Acquisition, and Innovation
Authors: Kim Kwangsoo , Li Fan , Yoo Jae Wook , Kim Choo Yeon
Published: July 2020

The purpose of this study is to investigate the mediation effects of external knowledge acquisition on the relationships between environments (dynamism, complexity, and hostility) and innovation. Although prior studies have extensively examined the relationships between environments and innovation or innovativeness, the results of the studies appear to lack consistency. To help clarify the relationships between environments and innovation, this study intends to examine the impact of environments on innovation through external knowledge acquisition, and it is argued that environments are likely to motivate or force firms to acquire new knowledge from the outside, which, in turn, tends to enhance their ability to innovate. Based on data collected from manufacturing SMEs in China through a questionnaire survey, we have found that dynamism, complexity and hostility have all positive total effects on innovation and that they also have positive influences on firms’ external knowledge acquisition. Besides, we have found that external knowledge acquisition has a complete mediation effect on the relationships between all three environmental dimensions and innovation. The results further show that the positive direct effects of all three environmental dimensions on innovation disappear completely when external knowledge acquisition is considered as a mediator. These results imply that the significant relationships between three respective environmental dimensions and innovation demonstrated in prior studies may be spurious. Based on these findings, we have presented key conclusions, implications, and limitations with the direction of future research.
THE RESEARCH OF MULTILAYER OUTER FENCING INCLUDING MATERIALS USING ASH AND SLAG WASTE OF THERMAL POWER PLANTS
Authors: Medvedeva G. , Lifant'eva A.F. A.
Published: July 2020

the most important direction of resource saving in construction is the widespread use of secondary material resources, which are waste products. The use of secondary products of industry as raw materials for the production of various building materials is very important, because it provides production with rich sources of cheap and, often, already prepared raw materials; lead to lower costs for the production of some building materials, and therefore saves capital investments intended for the construction of buildings and structures; release large areas of land and reduce the impact on the environment. The article deals with heat-insulating and structural-heat-insulating materials, with partial replacement of components by ash-slag waste (ASW): lightweight concretes with broken glass and concretes modified with sulfur. Properties of concretes modified with sulfur are investigated: compressive strength, density and thermal conductivity. In accordance with the obtained properties, a comparative characteristics of the received materials with existing building materials was carried out: sulfur modified concrete and lightweight concrete; lightweight concrete using broken glass and claydite-concrete. Thermophysical calculation of multilayer hencing is made. In each of the options, one of the following materials was selected as a structural and heat-insulating material: lightweight concrete using broken glass and sulfur modified concrete. Also, for each type of hencing, the necessary heat-insulating and structural materials were selected. In the economic part, the cost of the raw materials necessary to obtain 1 m3 of the investigated materials and the cost of 1 m3 of multilayer hencing, which includes the investigated concrete, are calculated.
Tirinhas em situações de ensino e o alcance do leitor
Authors: Buin Edilaine , Meneguini Bianca Estefani
Published: July 2020

Este artigo é resultado da análise das propostas referentes à leitura de tirinhas em um 6º ano de uma escola pública em Amambai-MS. Observando 73 tirinhas trabalhadas ao longo do ano, verifi ca-se quantitativamente que: (i) a maioria das atividades trata as tirinhas como gêneros discursivos, focalizando aspectos relevantes de leitura; (ii) a minoria é utilizada como pretexto para o ensino de gramática. Embora isso represente um quadro positivo, ainda se negligencia a questão da leitura em várias atividades. Na condução do uso do material didático, observa-se que se dedica maior tempo às atividades mais próximas da tradição gramatical, embora representem a minoria. Esse tipo de encaminhamento parece funcionar como clichê, lugar de esvaziamento dos sentidos. Fazer do aluno um leitor é estar diante da possibilidade de se perder, ao fugir do que é corriqueiro – risco do qual muitos se distanciam, apesar de duas décadas de orientações inovadoras nos documentos oficiais.
COMPORTAMIENTO PRODUCTIVO DE HIBRIDOS F1 DE TOMATE Y SUS POBLACIONES F2
Authors: Magaña-Lira Natanael , Peña-Lomelí Aureliano , Sánchez-del Castillo Felipe , Rodríguez-Pérez Juan E. , Moreno-Pérez Esaú del C.
Published: July 2020

En México se han desarrollado sistemas súper intensivos de producción de tomate (Lycopersicon esculentum Mill.) que demandan altas cantidades de semilla. La semilla de los híbridos comerciales de tomate es cara, por lo que es necesario explorar alternativas que ayuden a reducir los costos de semilla para esos sistemas de producción. El objetivo del presente estudio fue analizar el comportamiento productivo de siete híbridos comerciales (F1) de tomate tipo ‘‘bola’’ y de sus respectivas segundas generaciones filiales (F2), en un sistema súper intensivo de producción. El experimento se estableció con hidroponía bajo invernadero. Se utilizó una densidad de 25 plantas/m2 y se aplicó una poda para dejar un racimo por planta. Se evaluó rendimiento, número de frutos por planta, peso promedio por fruto en dos cortes, peso total, y la proporción de frutos firmes a los 45 d después del corte, como un indicador de vida poscosecha. Seis híbridos no cambiaron significativamente su rendimiento total de una generación filial a la siguiente. La F2 de ‘Badro’ rindió 57 % más que la F1. Con base en el rendimiento total por planta, es posible utilizar semilla de la F2 de las variedades ‘Sedona’, ‘Monte Verde’, ‘Badro’, ‘Charleston’ y ‘Lorena’, aun cuando aumenta la heterogeneidad en tamaño y número de frutos. En vida poscosecha, el único híbrido que presentó diferencias entre generaciones fue ‘Lorena’, cuya proporción de frutos firmes fue menor en la F2 que en F1. Los híbridos ‘Monte Verde’ y ‘Caimán’ presentaron los comportamientos más homogéneos entre las dos generaciones.
REACCIÓN DE GERMOPLASMA DE SOYA A Phakopsora pachyrhizi EN CAMPO
Authors: Peña-del-Río María de los Ángeles , Maldonado-Moreno Nicolás , Díaz-Franco Arturo
Published: July 2020

La roya asiática (Phakopsora pachyrhizi) de la soya (Glycine max (L.) Merr.), hizo su aparición en 2005 en México. Las variedades comerciales comúnmente sembradas han mostrado susceptibilidad al patógeno, por lo que el presente estudio tuvo el objetivo buscar fuentes de resistencia genética a la enfermedad, a través de la reacción de 197 genotipos de soya evaluados en campo. Se establecieron dos fechas de siembra (24 de febrero y 24 de abril, 2007) y las inoculaciones se hicieron a inicio de la floración. La severidad se evaluó en la etapa R6, mediante una escala de 1(0 %) a 3 (> 30 %). Se identificaron 23 genotipos de soya resistentes a P. pachyrhizi, en ambas fechas de siembra, los cuales no exhibieron lesiones foliares.
COMPORTAMIENTO POSTCOSECHA DE FRUTOS DE AGUACATE ‘HASS’ AFECTADO POR TEMPERATURA Y ATMÓSFERA MODIFICADA CON MICROPERFORADO
Authors: Espinosa-Cruz C. Cristóbal , Valle-Guadarrama Salvador , Ybarra-Moncada Ma. Carmen , Martínez-Damián M. Teresa
Published: July 2020

El fruto de aguacate (Persea americana Mill.) ‘Hass’ puede manejarse con refrigeración y atmósferas modificadas (AM) en postcosecha, pero las AM pueden causar metabolismo fermentativo por disponibilidad insuficiente de O2, lo que hace necesario controlar el intercambio gaseoso en el envase; esto último puede atenderse con microperforado. El objetivo del trabajo fue evaluar el efecto de baja temperatura y AM con envase microperforado en el comportamiento postcosecha de frutos de aguacate ‘Hass’. Se usaron recipientes de tereftalato de polietileno (PET) de 1.87 L con 0, 2, 4, 6 y 8 orificios de 200 μm en las paredes, con lotes de tres frutos y peso total de 550.0 (± 34.2) g, donde al variar el número de perforaciones se pudo controlar la concentración de O2 en los envases. El uso de microperforado con 4 y 2 orificios fue adecuado para manejar los frutos a 18 y 5 °C, con O2 en concentración de 3.5 y 4.0 %, respectivamente, pues se redujo pérdida de peso, velocidad de ablandamiento, velocidad de cambio de color y la actividad fermentativa, con relación a un almacenamiento en aire normal.
SILENCIAMIENTO GÉNICO EN PLANTAS: MECANISMOS MOLECULARES DEL ARN DE INTERFERENCIA Y APLICACIONES BIOTECNOLÓGICAS
Authors: Ricaño-Rodríguez Jorge , Zavala-González Ernesto A. , Ramírez-Lepe Mario
Published: July 2020

Las moléculas de ácido ribonucleico de cadena corta, que forman parte del mecanismo de ARN de interferencia (RNAi), son secuencias de ribonucleótidos que regulan la expresión a nivel traduccional de genes eucariontes. El silenciamiento génico mediado por RNAi, se refiere al proceso que permite, mediante complementariedad entre una molécula de ARN de interferencia y un ARN transcrito, promover la degradación de este último así como la reducción de sus niveles de traducción. Existen dos clases principales de moléculas ARN reguladoras que llevan a cabo dicho fenómeno: ARN de interferencia corto (siRNA) y microARN (miRNA). Ambas son generadas a partir del rompimiento de monómeros de ARN de doble cadena por una enzima ribonucleasa denominada DICER perteneciente a la familia de las ARNasas III, que genera fragmentos entre 17-25 nucleótidos. A nivel transcripcional, el ARN de interferencia promueve un complejo proceso de metilación de ADN (adición de un grupo metilo a la molécula), el cual conduce a una transformación de la eucromatina en heterocromatina en una posición fija del cromosoma (locus). A nivel post-transcripcional, el fenómeno de silenciamiento se origina mediante la intervención de una molécula de RNAi. El complejo de silenciamiento ARN-inducido (RISC) resultante permite la vinculación al ARN mensajero (mRNA) diana. En plantas, las secuencias RNAi reguladoras en posición cis se encuentran involucradas en mecanismos de defensa contra organismos antagonistas y transposones, mientras que aquéllas en posición trans, interceden en la expresión de genes relacionados con su crecimiento. De igual manera, algunas respuestas adaptativas a estrés se regulan por el miRNA. La presente revisión recopila de forma detallada algunos de los avances más importantes en el conocimiento del RNAi, e incluye antecedentes sobre su relación con el metabolismo de las plantas. Asimismo, se discuten progresos recientes en el entendimiento de su mecanismo molecular al igual que algunas aplicaciones biotecnológicas.
O Estudo do Meio como Metodologia de Ensino
Authors: Andrade André Benatti de , Marcellino Nelson Carvalho
Published: July 2020

Este trabalho busca fazer aproximações entre os conceitos de “estudo do meio”, ou EM, e de lúdico, com o intuito de aprimorar essa metodologia de ensino relacionada à vivência da aula não formal. Nosso objetivo é colaborar com o entendimento do EM com base nas características do lúdico. O trabalho foi desenvolvido pela combinação das pesquisas bibliográfica e de campo. A pesquisa de campo foi realizada em Campinas, SP – cidade em que os estudos do meio têm se apresentado como alternativa cada vez mais frequente. O estudo envolveu 78 participantes entre professores, coordenadores, animadores socioculturais e gestores de agências por meio de questionário com 16 perguntas sobre estudo do meio e o lúdico. Entre outros itens, concluímos que existe, em alguns pontos, um distanciamento entre discurso e ação e que o lazer não é bem incorporado ao EM, mesmo tendo, a partir de seu conceito, uma aproximação interessante com a educação.
Effects of Relaxation Therapy Using Music on Breast Milk Production in Postpartum Mothers
Authors: Widyantari Kadek Yuke
Published: July 2020

Introduction: Low milk production is one of the main reasons mothers do not provide breast milk exclusively. Relaxation therapy interventions are expected to help increase milk production. Purpose: The purpose of this scoping review is to map available evidence related to the effect of relaxation therapy interventions on breast milk production in postpartum mothers. Methods: In this scoping review, the authors identify studies that explain the effect of relaxation therapy on breast milk production in postpartum mothers from three databases (PubMed, Wiley, and Science Direct). Searches are limited to studies published in English and present data for the period 2010-2019. The identified study was reviewed using the PRISMA Flowchart. Studies with quantitative designs related to the effect of relaxation therapy on the production of breast milk are then selected for review. Results: From a total of four articles that have been reviewed two sub-themes are found, relaxation therapy increases milk production (increased success of breastfeeding, increased milk secretion and fat content in breast milk) and relaxation therapy decreases maternal stress levels (decreases stress scores and cortisol levels). Conclusion: From this review, some evidences shows music therapy is effective in significantly increase milk production. All studies included in the review have limitations related to the research design or sample collection procedures. The method of relaxation therapy is simple, inexpensive, and easy to use without the involvement of hospital staff. Regarding the intervention, all the intervention groups in this study showed a significant effect compared to the control group.

Keywords: Music Therapy, Relaxation Therapy, Breastfeeding, Lactating
A violência segundo os mestres da suspeita
Authors: Dos Santos Nadson Vinícius
Published: July 2020

as obras de Freud, Marx e Nietzsche constituem pontos de partida para a crítica da racionalidade ocidental. Neste artigo, analisam-se as reflexões desses pensadores a respeito da violência humana relacionando-as com a literatura de testemunho. Nesse sentido, são observadas as considerações a respeito da moral ocidental, da relação entre razão e instinto, da vontade de poder, da violência socioeconômica e da ideologia como falsa consciência.
Le amministrative 2019 a Firenze e le cifre del PD
Authors: Corica Graziana
Published: July 2020

The 2019 municipal elections in Florence confirm the electoral success of the Democratic Party and the Mayor, Dario Nardella. The center-right candidate, Ubaldo Bocci, an entrepreneur and member of local catholic associations, collected 25% of the votes. The Five Star Movement, with Roberto De Blasi as mayoral candidate, and the left candidate Antonella Bundu got about 7% of the electoral preferences each.In which areas of the city did the PD win? Is it possible establish a causal relation between voting behaviour, the neighbourhood and sociodemographic variables? To answer these questions, the article examines the electoral results through a geographical approach, based on the 72 «elementary areas» of Florence and other variables provided by ISTAT. This analysis identifies four macro-areas, distinguished for the different combinations of the presence of the political parties. Overall, the preferences collected by the PD, more than 50%, make difficult to found a link between the vote and the social background.In order to understand the electoral success of the PD and of local politicians other factors, like political culture or specific contextual features, have to be taken into consideration. Indeed, from a qualitative perspective, this contribution suggests to consider Florence as a «urban regime», composed by several actors who share interests and visions about the growth of the city.
Luglio-Dicembre 2018
Authors: Rombi Stefano
Published: July 2020

Review of elections around the world, July 2018 - December 2018
SEMICONDUCTOR CONDUCTIVITY
Authors: Gulhayo Oybekovna Akbarova
Published: July 2020

In given article has been expressed solids, free carriers during their motion continuously experience collisions with atoms and ions of impurities and various defects, as a result, free carriers scatter as well.
KEY WORDS: semiconductor, conductivity, source, ion, experience, atoms.
Escenarios de la experiencia estética en el aprendizaje
Authors: Rubio Pardo Luis Alfonso
Published: July 2020

El presente artículo se propone describir y examinar algunas experiencias escolares vividas durante la realización de un trabajo que propone la vinculación de la música y la literatura como elemento esencial para la enseñanza de la asignatura de lengua castellana, procurando forjar un espacio para el surgimiento de una experiencia estética que reúnan al estudiante, al maestro y a la escuela en un proceso formativo cada vez más significativo e integral.
Una propuesta para el desarrollo del vocabulario en inglés en el Marco de la educación inclusiva
Authors: Garibotto Trujillo Vivian Camila , Ramos Rodríguez Nelly Yazmin , Ríos Castro Camila Alejandra
Published: July 2020

La siguiente investigación pretende identificar estilos de aprendizaje de los estudiantes de grado sexto del colegio I.E. La Merced (municipio de Mosquera), de igual manera conocer las perspectivas de los docentes sobre la enseñanza del inglés en el marco de la educación inclusiva y las estrategias que utilizan para la enseñanza de vocabulario de lengua extranjera, la investigación se realizó bajo un enfoque cualitativo con el método IAP, y se logró identificar el estilo de aprendizaje que más prevalece y el que menos sobresale.
An Analysis of Code Mixing in Bayu Skak’s Videos
Authors: Hasanah Raudatul
Published: July 2020

This study investigated the types and factors that influence code mixing in Bayu Skak’s videos. The data in this study are in the form of utterances that contain code mixing in Bayu Skak’s videos. This research was conducted by analyzing the data qualitatively. The research instruments are the researcher herself. There were three videos that was used in this research. The techniques of data collection were done by watching Bayu Skak’s videos one by one, noting down the utterances that contained code mixing, and giving numbers and codes in every utterance that contained code mixing and analysing the data based on Spradley’s theory (1965). The steps of data analysis are domain analysis, taxonomy analysis, componential analysis, and cultural values. The finding of the research described types and factors that influence the code mixing and the total data showed thirty two data used code mixing from types of code mixing which attained eleven data from insertion, eight data of alternation, and eleven data of congruent lexicalization. Then, factors that influence code mixing cover four need for synonymy, four data of social value, three data of intrduction and development of new culture, five data of low frequency or word, five data of oversight, five data of pernicious homonymy, four data of in sufficiently differentiated, and two data of end.