bluuebunny/crossref_metadata_2025 huggingface dataset:
The Conformational Contribution to Molecular Complexity and Its Implications for Information Processing in Living Beings and Chemical Artificial Intelligence
Authors: Gentili Pier Luigi
Published: February 2024

This work highlights the relevant contribution of conformational stereoisomers to the complexity and functions of any molecular compound. Conformers have the same molecular and structural formulas but different orientations of the atoms in the three-dimensional space. Moving from one conformer to another is possible without breaking covalent bonds. The interconversion is usually feasible through the thermal energy available in ordinary conditions. The behavior of most biopolymers, such as enzymes, antibodies, RNA, and DNA, is understandable if we consider that each exists as an ensemble of conformers. Each conformational collection confers multi-functionality and adaptability to the single biopolymers. The conformational distribution of any biopolymer has the features of a fuzzy set. Hence, every compound that exists as an ensemble of conformers allows the molecular implementation of a fuzzy set. Since proteins, DNA, and RNA work as fuzzy sets, it is fair to say that life’s logic is fuzzy. The power of processing fuzzy logic makes living beings capable of swift decisions in environments dominated by uncertainty and vagueness. These performances can be implemented in chemical robots, which are confined molecular assemblies mimicking unicellular organisms: they are supposed to help humans “colonise” the molecular world to defeat diseases in living beings and fight pollution in the environment.
Conjugated Oligoelectrolyte with DNA Affinity for Enhanced Nuclear Imaging and Precise DNA Quantification
Authors: Zhang Xinmeng , Zhou Cheng , Hou Jianxun , Feng Gang , Xu Zhourui , Shao Yonghong , Yang Chengbin , Xu Gaixia
Published: February 2024

Precise DNA quantification and nuclear imaging are pivotal for clinical testing, pathological diagnosis, and drug development. The detection and localization of mitochondrial DNA serve as crucial indicators of cellular health. We introduce a novel conjugated oligoelectrolyte (COE) molecule, COE-S3, featuring a planar backbone composed of three benzene rings and terminal side chains. This unique amphiphilic structure endows COE-S3 with exceptional water solubility, a high quantum yield of 0.79, and a significant fluorescence Stokes shift (λex = 366 nm, λem = 476 nm), alongside a specific fluorescence response to DNA. The fluorescence intensity correlates proportionally with DNA concentration. COE-S3 interacts with double-stranded DNA (dsDNA) through an intercalation binding mode, exhibiting a binding constant (K) of 1.32 × 106 M−1. Its amphiphilic nature and strong DNA affinity facilitate its localization within mitochondria in living cells and nuclei in apoptotic cells. Remarkably, within 30 min of COE-S3 staining, cell vitality can be discerned through real-time nuclear fluorescence imaging of apoptotic cells. COE-S3’s high DNA selectivity enables quantitative intracellular DNA analysis, providing insights into cell proliferation, differentiation, and growth. Our findings underscore COE-S3, with its strategically designed, shortened planar backbone, as a promising intercalative probe for DNA quantification and nuclear imaging.
Enhanced Nanozymatic Activity on Rough Surfaces for H2O2 and Tetracycline Detection
Authors: Alsulami Tawfiq , Alzahrani Abdulhakeem
Published: February 2024

The needless use of tetracyclines (TCs) in foodstuffs is a huge health concern in low- and middle-income and Arab countries. Herein, a sensitive and faster monitoring system for H2O2 and TCs is proposed, utilizing the large surface-to-volume ratio of a non-spherical gold nanoparticle/black phosphorus nanocomposite (BP-nsAu NPs) for the first time. BP-nsAu NPs were synthesized through a single-step method that presented nanozymatic activity through 3,3′,5,5′-Tetramethylbenzidine (TMB) oxidation while H2O2 was present and obeyed the Michaelis–Menten equation. The nanozymatic activity of the BP-nsAu NPs was enhanced 12-fold and their detection time was decreased 83-fold compared to conventional nanozymatic reactions. The proposed method enabled us to quantify H2O2 with a limit of detection (LOD) value of 60 nM. Moreover, target-specific aptamer-conjugated BP-nsAu NPs helped us detect TCs with an LOD value of 90 nM. The present strategy provides a proficient route for low-level TC monitoring in real samples.
Jugular Foramen Tumors: Surgical Strategies and Representative Cases
Authors: Castillo Andrea L. , Meybodi Ali Tayebi , Liu James K.
Published: February 2024

(1) Background: Jugular foramen tumors are complex lesions due to their relationship with critical neurovascular structures within the skull base. It is necessary to have a deep knowledge of the anatomy of the jugular foramen and its surroundings to understand each type of tumor growth pattern and how it is related to the surrounding neurovascular structures. This scope aims to provide a guide with the primary surgical approaches to the jugular foramen and familiarize the neurosurgeons with the anatomy of the region. (2) Methods and (3) Results: A comprehensive description of the surgical approaches to jugular foramen tumors is summarized and representative cases for each tumor type is showcased. (4) Conclusions: Each case should be carefully assessed to find the most suitable approach for the patient, allowing the surgeon to remove the tumor with minimal neurovascular damage. The combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach can be performed in a stepwise fashion for the resection of complex jugular foramen tumors.
Revealing the Complexity of Fatigue: A Review of the Persistent Challenges and Promises of Artificial Intelligence
Authors: Rudroff Thorsten
Published: February 2024

Part I reviews persistent challenges obstructing progress in understanding complex fatigue’s biology. Difficulties quantifying subjective symptoms, mapping multi-factorial mechanisms, accounting for individual variation, enabling invasive sensing, overcoming research/funding insularity, and more are discussed. Part II explores how emerging artificial intelligence and machine and deep learning techniques can help address limitations through pattern recognition of complex physiological signatures as more objective biomarkers, predictive modeling to capture individual differences, consolidation of disjointed findings via data mining, and simulation to explore interventions. Conversational agents like Claude and ChatGPT also have potential to accelerate human fatigue research, but they currently lack capacities for robust autonomous contributions. Envisioned is an innovation timeline where synergistic application of enhanced neuroimaging, biosensors, closed-loop systems, and other advances combined with AI analytics could catalyze transformative progress in elucidating fatigue neural circuitry and treating associated conditions over the coming decades.
Effects of Transcranial Direct Current Stimulation on Clinical Features of Dizziness and Cortical Activation in a Patient with Vestibular Migraine
Authors: Yeo Sang Seok , Kim Chang Ju , Yun Seong Ho , Son Sung Min , Kim Yoon Jae
Published: February 2024

Background: Vestibular migraine (VM) is common migraine that occurs in patients with dizziness. Vestibular rehabilitation for managing VM generally remains unclear. Recently, it has been reported that transcranial direct current stimulation (tDCS) has positive effects in alleviating dizziness. This study investigated the effects of tDCS on dizziness and cortical activation in a patient with VM. Methods: We recruited a male patient aged 31 years with no dizziness. The patient watched a video to induce dizziness using a virtual reality device. The study applied the intervention using tDCS for 4 weeks and measured 4 assessments: functional near-infrared spectroscopy (fNIRS), quantitative electroencephalography (qEEG), dizziness handicap inventory, and visual vertigo analog scale. Results: We showed the activation in the middle temporal gyrus and inferior temporal gyrus (ITG) of the left hemisphere and in the superior temporal gyrus and ITG of the right hemisphere in the pre-intervention. After the intervention, the activation of these areas decreased. In the results of qEEG, excessive activation of C3, P3, and T5 in the left hemisphere and C4 in the right hemisphere before intervention disappeared after the intervention. Conclusions: This study indicated that tDCS-based intervention could be considered a viable approach to treating patients with vestibular dysfunction and dizziness caused by VM.
Influence of Inherited Seizure Susceptibility on Intermittent Voluntary Alcohol Consumption and Alcohol Withdrawal Seizures in Genetically Epilepsy-Prone Rats (GEPR-3s)
Authors: Silva-Cardoso Gleice Kelli , N’Gouemo Prosper
Published: February 2024

Background: The link between epilepsy and alcohol consumption is complex, with conflicting reports. To enhance our understanding of this link, we conducted a study to determine how inherited seizure susceptibility affects voluntary alcohol consumption and influences alcohol withdrawal seizures in male and female genetically epilepsy-prone rats (GEPR-3s) compared to Sprague Dawley (SD) rats. Methods: In the first experiment, animals were given access to two bottles simultaneously, one containing water and the other 7.5%, 15%, or 30% (v/v) alcohol three times a week for each dose after acclimation to drinking water. In a second experiment, animals were tested for acoustically evoked alcohol seizures 24 h after the last session of voluntary alcohol consumption. Results: Analysis revealed that GEPR-3s (males and females) had lower alcohol intake and preference than SD rats, particularly at lower alcohol concentrations. However, female GEPR-3s consumed more alcohol and had a higher alcohol preference than males. Furthermore, withdrawal from voluntary alcohol consumption facilitated the onset and duration of seizures in GEPR-3s. Conclusions: Our study suggests that genetic seizure susceptibility in GEPR-3s is negatively associated with alcohol consumption. However, withdrawal from low to moderate amounts of alcohol intake can promote epileptogenesis in the epileptic GEPR-3s.
Promoting or Prohibiting? Investigating How Time Pressure Influences Innovative Behavior under Stress-Mindset Conditions
Authors: Zhou Yufan , Zhang Jianwei , Zheng Wenfeng , Fu Mengmeng
Published: February 2024

The existing empirical evidence on the relationship between time pressure and innovative behavior is paradoxical. An intriguing yet unresolved question is “When does time pressure promote or prohibit innovative behavior, and how?” We theorize that the paradoxical effect of time pressure on innovative behavior can be elucidated by the moderating role of stress mindset, and we also explore the mediating role of thriving at work. Our research involved a field study of 390 research and development personnel from eight enterprises and research institutes in China to test our proposed model. Results indicated that the stress-is-debilitating mindset negatively moderated the association between time pressure and thriving at work, while the stress-is-enhancing mindset positively moderated the link between time pressure and thriving at work. Furthermore, the findings demonstrated that the stress-is-debilitating mindset negatively moderated the indirect impact of time pressure on employees’ innovative behavior through thriving at work, while the stress-is-enhancing mindset positively moderated the indirect effect of time pressure on employees’ innovative behavior through thriving at work. The theoretical and practical implications of these findings are also discussed.
Immobilization of Alcohol Dehydrogenases on Silica-Based Supports and Their Application in Enantioselective Ketone Reductions
Authors: Armani Daria , Piccolo Oreste , Petri Antonella
Published: February 2024

The use of immobilized alcohol dehydrogenases (ADHs) offers numerous advantages, especially in the reaction conditions required by industrial applications. Looking for more efficient and cost-effective methods of ADH immobilization, in this study we explored silica-based supports as an alternative to the use of functionalized polymeric resins. Three commercially available ADHs were immobilized by adsorption and covalent bond formation. The obtained supported biocatalysts were applied for the bioreduction of acetophenone and some derivatives with good yields and excellent enantioselectivity. The important intermediate (S)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol was obtained with a high enantiomeric excess (>99%) by using the highest performing immobilized ADH sample. The reusability of this biocatalyst was investigated in a flow system for five consecutive runs; the experiments showed that the biocatalyst could be recycled without a loss of activity and enantioselectivity. Finally, cross-linking with the glutaraldehyde of the supported biocatalyst was also carried out to prevent the leaching of the enzyme during the catalytic reactions.
Templated Synthesis of Cu2S Hollow Structures for Highly Active Ozone Decomposition
Authors: Jiang Yishan , Xu Ying , Zhang Qichao , Zhao Xin , Xiao Feng , Wang Xinbo , Ma Guojun
Published: February 2024

Nowadays, it is highly desired to develop highly active and humidity-resistive ozone decomposition catalysts to eliminate the ozone contaminant, one of the primary pollutants in the air. In this work, a series of Cu2S hollow structured materials were rapidly synthesized using different structured Cu2O templates. The Cu2S from porous Cu2O showed the highest ozone catalytic decomposition efficiency of >95% to 400 ppm ozone with a weight hourly space velocity of 480,000 cm3·g−1·h−1 in dry air. Importantly, the conversion remained >85% in a high relative humidity of 90%. The mechanism was explored by diffusive reflectance infrared spectroscopy which showed the decomposition intermediate of O22−, and X-ray photoelectron spectroscopy revealed the dual active site of both Cu and S. The EPR and UPS characterization results also explained the superiority of porous Cu2S catalysts from the material itself. All these results show the effective decomposition of ozone by Cu2S, especially in harsh environments, promising for active ozone elimination.
Quantum Dot Imaging Agents: Haematopoietic Cell Interactions and Biocompatibility
Authors: Naylor-Adamson Leigh , Price Thomas W. , Booth Zoe , Stasiuk Graeme J. , Calaminus Simon D. J.
Published: February 2024

Quantum dots (QDs) are semi-conducting nanoparticles that have been developed for a range of biological and non-biological functions. They can be tuned to multiple different emission wavelengths and can have significant benefits over other fluorescent systems. Many studies have utilised QDs with a cadmium-based core; however, these QDs have since been shown to have poor biological compatibility. Therefore, other QDs, such as indium phosphide QDs, have been developed. These QDs retain excellent fluorescent intensity and tunability but are thought to have elevated biological compatibility. Herein we discuss the applicability of a range of QDs to the cardiovascular system. Key disease states such as myocardial infarction and stroke are associated with cardiovascular disease (CVD), and there is an opportunity to improve clinical imaging to aide clinical outcomes for these disease states. QDs offer potential clinical benefits given their ability to perform multiple functions, such as carry an imaging agent, a therapy, and a targeting motif. Two key cell types associated with CVD are platelets and immune cells. Both cell types play key roles in establishing an inflammatory environment within CVD, and as such aid the formation of pathological thrombi. However, it is unclear at present how and with which cell types QDs interact, and if they potentially drive unwanted changes or activation of these cell types. Therefore, although QDs show great promise for boosting imaging capability, further work needs to be completed to fully understand their biological compatibility.
New Insights on the Male and Female Reproductive Organs of Centrorhynchus globocaudatus (Acanthocephala), Intestinal Parasite of Birds of Prey
Authors: Sayyaf Dezfuli Bahram , Pironi Flavio , Rossetti Emanuele , Herlyn Holger
Published: February 2024

Acanthocephalans are dioecious parasites that gain sexual maturity in the alimentary canal of their definitive hosts (gnathostome vertebrates). This initial survey by light and transmission electron microscopy was conducted on the functional organization of the ovarian balls and uterine bell in mature females and on Saefftigen’s pouch and the copulatory bursa in males. We studied these structures via the example of Centrorhynchus globocaudatus (Palaeacanthocephala) in Falco tinnunculus and Buteo buteo, from the Province of Ferrara (Northern Italy). Our study confirms that the ovarian balls have surface microvilli and consist of a multinucleate supporting syncytium and a cellular region with oogonial syncytium, single germ cells, zygotes, and shelled eggs. Germ cells are embedded in the supporting syncytium. The ultrastructural features of these components and data on fertilization, shell formation, and release from the ovarian ball, alongside insights into the likely egg sorting function of the uterine bell, are provided. We also present light and electron microscopy observations of Saefftigen’s pouch and a suggestion regarding its hydrostatic functioning in the eversion of the copulatory bursa.
Effect of LDL Extracted from Human Plasma on Membrane Stiffness in Living Endothelial Cells and Macrophages via Scanning Ion Conductance Microscopy
Authors: Kiseleva Diana , Kolmogorov Vasilii , Cherednichenko Vadim , Khovantseva Ulyana , Bogatyreva Anastasia , Markina Yuliya , Gorelkin Petr , Erofeev Alexander , Markin Alexander
Published: February 2024

Mechanical properties of living cells play a crucial role in a wide range of biological functions and pathologies, including atherosclerosis. We used low-stress Scanning Ion-Conductance Microscopy (SICM) correlated with confocal imaging and demonstrated the topographical changes and mechanical properties alterations in EA.hy926 and THP-1 exposed to LDL extracted from CVD patients’ blood samples. We show that the cells stiffened in the presence of LDL, which also triggered caveolae formation. Endothelial cells accumulated less cholesterol in the form of lipid droplets in comparison to THP-1 cells based on fluorescence intensity data and biochemical analysis; however, the effect on Young’s modulus is higher. The cell stiffness is closely connected to the distribution of lipid droplets along the z-axis. In conclusion, we show that the sensitivity of endothelial cells to LDL is higher compared to that of THP-1, triggering changes in the cytoskeleton and membrane stiffness which may result in the increased permeability of the intima layer due to loss of intercellular connections and adhesion.
Synthesis of ZnS/Al2O3/TaSe2 Core/Shell Nanowires Using Thin Ta Metal Film Precursor
Authors: Polyakov Boris , Kadiwala Kevon , Butanovs Edgars , Dipane Luize , Trausa Annamarija , Bocharov Dmitry , Vlassov Sergei
Published: February 2024

This study introduces a novel approach for fabricating ZnS/Al2O3/TaSe2 heterostructured core/shell nanowires (NWs) through the selenization of a metallic Ta thin film precursor. The synthesis process involves a meticulously designed four-step protocol: (1) generating ZnS NWs on an oxidized silicon substrate, (2) encapsulating these NWs with a precisely controlled thin Al2O3 layer via atomic layer deposition (ALD), (3) applying a Ta precursor layer by magnetron sputtering, and (4) annealing in a Se-rich environment in a vacuum-sealed quartz ampoule to transform the Ta layer into TaSe2, resulting in the final core/shell structure. The characterization of the newly produced NWs using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) was validated using the integrity and composition of the heterostructures. Our method not only establishes a new pathway for the synthesis of TaSe2-based core/shell NWs but also extends the potential for creating a variety of core/shell NW systems with chalcogenide shells by adapting the thin film metal precursor approach. This versatility opens the way for future advancements in nanoscale material applications, particularly in electronics and optoelectronics where core/shell geometries are increasingly important.
RepDwNet: Lightweight Deep Learning Model for Special Biological Blood Raman Spectra Analysis
Authors: He Jiongheng , Zhou Rigui , Ren Pengju , Li Yaochong , Xiong Shengjun
Published: February 2024

The Raman spectroscopy analysis technique has found extensive applications across various disciplines due to its exceptional convenience and efficiency, facilitating the analysis and identification of diverse substances. In recent years, owing to the escalating demand for high-efficiency analytical methods, deep learning models have progressively been introduced into the realm of Raman spectroscopy. However, the application of these models to portable Raman spectrometers has posed a series of challenges due to the computational intensity inherent to deep learning approaches. This paper proposes a lightweight classification model, named RepDwNet, for identifying 28 different types of biological blood. The model integrates advanced techniques such as multi-scale convolutional kernels, depth-wise separable convolutions, and residual connections. These innovations enable the model to capture features at different scales while preserving the coherence of feature data to the maximum extent. The experimental results demonstrate that the average recognition accuracy of the model on the reflective Raman blood dataset and the transmissive Raman blood dataset are 97.31% and 97.10%, respectively. Furthermore, by applying structural reparameterization to compress the well-trained model, it maintains high classification accuracy while significantly reducing the parameter size, thereby enhancing the speed of classification inference. This makes the model more suitable for deployment in portable and mobile devices. Additionally, the proposed model can be extended to various Raman spectroscopy classification scenarios.
Bone Deformities through the Prism of the International Classification of Functioning, Disability and Health in Ambulant Children with Cerebral Palsy: A Systematic Review
Authors: Bailly Rodolphe , Pons Christelle , Haes Anne-Charlotte , Nguyen Lisa , Thepaut Matthias , Houx Laëtitia , Lempereur Mathieu , Brochard Sylvain
Published: February 2024

(1) Aim: The aim of this study was to determine the relationship between lower limb bone deformities and body functions, activity, and participation in ambulant children with CP and whether changing bone morphology affects outcomes in these domains. (2) Methods: A systematic literature search (PROSPERO CRD42020208416) of studies reporting correlations between measures of lower limb bone deformities and measures of body function, activity or participation, or post-surgical outcomes in these domains was conducted from 1990 to 2023 in Medline, Scopus, and Cochrane Library. We assessed study quality with the Checklist for Case Series (CCS) and a quality assessment developed by Quebec University Hospital. Meta-analysis was not possible; therefore, descriptive synthesis was performed. (3) Results: A total of 12 of 3373 screened articles were included. No studies evaluated the relationships between bone deformities and activity or participation, or the effect of isolated bone surgery on these domains. Correlations between bone deformities and body functions were poor-to-moderate. Internal hip rotation during gait improved after femoral derotation osteotomy. (4) Conclusions: A shift in paradigm is urgently required for the research and management of bone deformities in children with CP to include the activity and participation domains of the ICF, as well as consider more psychological aspects such as self-image.
Attachment-Based Mentalization Profiles of Iranian Children: A Mixed-Method Approach
Authors: Zandpour Masoumeh , Lind Majse , Sharp Carla , Hasani Jafar , Bagheri Sheykhangafshe Farzin , Borelli Jessica L.
Published: February 2024

Mentalization, operationalized as reflective functioning (RF), is the ability to understand one’s own and another’s mental world implicitly or explicitly. RF is a newly discovered research field in Iran and is largely under-studied in Eastern cultures in general, underscoring the high need for cross-cultural studies in this field of research. A qualitative method was used to examine the ability to understand, process, and respond to high-arousal attachment situations in typical and clinical populations of Iranian children recruited from a Tehran primary school. A well-known semi-structured interview commonly used to assess RF in children was used to collect data. Required information on internalizing and externalizing symptoms, demographic information, and all formal diagnoses of children were collected by parents. The results indicated the identification of four different profiles of RF in children, one of which was adaptive, while the other three were maladaptive. Also, the results showed that typically developing children and those having a high social and economic status (SES) were characterized as having a more adaptive profile of RF, while children from the clinical population and those with a low SES reported a more maladaptive profile (passive mentalizing, helpless mentalizing, narcissistic mentalizing) of RF. The present study is an important step in increasing our understanding of the development of mentalization in children and has significant educational and clinical implications.
Hybrid Organic–Inorganic Biomaterials as Drug Delivery Systems: A Molecular Dynamics Study of Quercetin Adsorption on Amorphous Silica Surfaces
Authors: Raffaini Giuseppina , Pirozzi Pasqualina , Catauro Michelina , D’Angelo Antonio
Published: February 2024

Many important drugs in pharmaceutical applications are poorly soluble. Solubilization, which is diffusion through biological barriers, and the control of local administration are crucial steps for bioavailability and to avoid cytotoxic effects. Hybrid organic/inorganic biomaterials can incorporate drugs for in situ release after implantation. Molecular Mechanics (MM) and Molecular Dynamics (MD) simulations are useful tools for investigating intermolecular interactions between drug and biomaterial surfaces at the atomistic level for these applications. This work studies quercetin, a flavonoid drug important for its anti-inflammatory, antioxidant, and anticancer properties, and the amorphous SiO2 surface using a simulation protocol proposed in previous work related to ketoprofen drugs. After adsorption on the amorphous silica surface, the adsorption process of quercetin drug molecules at two different drug concentrations near a hydrated and then dried silica surface is investigated. Interestingly, these theoretical results are compared with experimental data obtained via Fourier Transform Infrared Spectroscopy (FT–IR) spectra related to quercetin molecules homogenously entrapped in a silica matrix obtained via the Sol–Gel method. Favorable H– bonds and some π–π interactions among drug molecules are crucial surface interactions for the new generation of biocompatible materials capable of incorporating anti-inflammatory agents for release into the human body.
Promising Antifungal Activity of Cedrela fissilis Wood Extractives as Natural Biocides against Xylophagous Fungi for Wood Artwork of Cultural Heritage
Authors: Vovchuk Camila Sofía , González Garello Tomás , Careaga Valeria Pilar , Fazio Alejandra Teresa
Published: February 2024

Xylophagous fungi are able to thrive inside wood because they produce enzymes that can degrade it and cause significant damage. Due to this process, in the case of wood that forms part of the structure of a building or furniture, xylophagous fungi pose a serious problem that needs to be addressed, as they can compromise the integrity and durability of the wood. The aim of this work was to obtain extractives from Cedrela fissilis wood in order to conduct a preliminary evaluation of their antifungal activity against xylophagous fungi Trametes trogii (white rot), Pycnoporus sanguineus (white rot), and Chaetomium globosum (soft rot). The antifungal activity of the extractives was evaluated against these xylophagous fungi through tests of growth fungal colonies with the extractives in Petri dishes. All the evaluated extractives showed antifungal activity against all the fungi tested, demonstrating their potential use as natural biocides for wood artwork of Cultural Heritage.
Micron-Smooth, Robust Hydrophobic Coating for Photovoltaic Panel Surfaces in Arid and Dusty Areas
Authors: Guo Rongrong , Wang Yuanhao , Lu Hao , Wang Shifeng , Wang Bohan , Zhang Qiyu
Published: February 2024

Photovoltaic (PV) power generation is a clean energy source, and the accumulation of ash on the surface of PV panels can lead to power loss. For polycrystalline PV panels, self-cleaning film is an economical and excellent solution. However, the main reasons why self-cleaning coatings are currently difficult to use on a large scale are poor durability and low transparency. It is a challenge to improve the durability and transparency of self-cleaning thin films for PV panel surface against ash accumulation. Therefore, in this paper, a resin composite film containing modified silica components was designed and synthesized, mainly by the organic/inorganic composite method. A transparent hydrophobic coating with nano-micro planar structures was constructed, which primarily relies on the hydrophobic properties of the compound itself to build the hydrophobic oleophobic coating. The layer has a micrometer-scale smooth surface structure and high transparency, with a 0.69% increase in light transmittance compared with uncoated glass, and the durability is good. It is mainly applied to the surface of photovoltaic devices, which can alleviate the dust accumulation problem of photovoltaic panels in arid, high-temperature, and dusty areas and reduce the maintenance cost of them.
Corrosion Behavior of Aluminum Alloys in Different Alkaline Environments: Effect of Alloying Elements and Anodization Treatments
Authors: Fabris Riccardo , Masi Giulia , Bignozzi Maria Chiara
Published: February 2024

Aluminum alloys are extensively used to manufacture mechanical components. However, when exposed to alkaline environments, like lubricants, refrigerants, or detergents, they can be corroded, reducing their durability. For this reason, the aim of this study is to investigate the influence of aggressive alkaline solutions (i.e., pH and presence of chlorides) on the corrosion resistance of three aluminum alloys (AA 5083-H111, AA 6082-T6, and AA 7075-T6) with and without anodizing treatments. Open circuit potential (EOCP) and anodic polarization measurements were carried out and typical corrosion parameters such as corrosion current density (icor) and corrosion rate (CR) were determined. Morphology of the corrosion attack and samples microstructure were investigated by scanning electron microscope. Results show that corrosion behavior of the three investigated alloys is influenced by (i) the aggressiveness of the testing environments; (ii) the thickness of the anodizing treatment; (iii) the alloy chemical composition; (iv) the distribution of intermetallic phases in the aluminum matrix. Moreover, three galvanic series have been built also testing other metallic alloys commonly used in mechanical applications, i.e., carbon steel (C40), stainless-steel (AISI 304), and Cu-based alloys (Cu-Ni alloy and CW 617 N, respectively). Results clearly indicate that galvanic series play a fundamental role when it is necessary to select an alloy for a specific environment, highlighting the thermodynamic conditions for corrosion occurrence. On the other hand, kinetic measurements and microstructural studies carried out on the three aluminum alloys stress the importance of the surface treatments and relevant thickness as well as the effect of metal exposure. Future work will involve the study of other surface treatments on aluminum alloys and the evaluation of their corrosion behavior in acidic environments.
Enhanced Biocidal Activity of Heterophase Zinc Oxide/Silver Nanoparticles Contained within Painted Surfaces
Authors: Bakina Olga , Pikuschak Elizaveta , Prokopchuk Anna , Evplonova Elena , Plaksina Tatiana , Avgustinovich Alexandra , Spirina Liudmila , Vorozhtsov Alexander , Yakovlev Nikolay , Lerner Marat
Published: February 2024

Today, one of the biggest challenges is infections in the painted walls of hospitals. Acrylic-based paints are a target of antibiotic-resistant microorganisms since they contain cellulosic compounds as thickeners. The aim of this study was to synthesize and investigate the biocidal activity and toxicity of heterophase ZnO-Ag nanoparticles fixed in water-based acrylic paint layers in reference to a nontreated water-based paint. The ZnO-Ag nanoparticles with average particle sizes of about 80 nm were simply obtained by electrical explosion of two twisted wires in an oxygen-containing atmosphere. The nanoparticles and modified paint were characterized using SEM, TEM, XPS, and XRD techniques. The antimicrobial activity of the nanoparticles and modified paint layers was tested against P. aeruginosa, S. aureus, MRSA, E. coli bacteria, and C. albicans using ISO 22196. The antiviral activity against smallpox virus was tested according to ISO 21702. Flow cytometry tests were used to investigate the toxicity of the modified paint coating. As-synthesized nanoparticles had “Janus-like” morphology, with a clear interface inside the nanoparticle. Nanoparticles had enhanced antibacterial activity, which is based on the nanoparticle photocatalytic activity in water decomposition and reactive oxygen species generation. The paint coating with a ZnO-Ag nanoparticle mass ratio of 1.0 wt.% displayed significant antibacterial activity (more than a 99% reduction) and 100% antifungal activity. In addition, this coating inactivates >99% of the virus after 2 h of contact relative to a nontreated control paint. The paint coating showed low toxicity against the sensitive 3T3 fibroblast cell line. More than 90% cell viability was observed after 24 h of incubation with the sample extract. Therefore, heterophase ZnO-Ag nanoparticles have high biocidal activity and low toxicity use and can be applied to other commercial water-based paints to improve their performance against pathogens.
The Icing Characteristics of a 1.5 MW Wind Turbine Blade and Its Influence on the Blade Mechanical Properties
Authors: Han Yexue , Lei Zhen , Dong Yuxiao , Wang Qinghui , Li Hailin , Feng Fang
Published: February 2024

Ice accumulation significantly impacts the mechanical properties of wind turbine blades, affecting power output and reducing unit lifespan. This study explores the icing characteristics and their effects on a 1.5 megawatt (MW) wind turbine blade’s mechanical properties under various conditions, including wind speeds of 5 m per second (m/s) and 10 m per second, temperatures of −5 degrees centigrade (°C) and −10 degrees centigrade, and different liquid water contents, by using icing wind tunnel tests and structural statics analysis. The research reveals that ice predominantly forms in an irregular pattern on the leading edge of the blade. It is easy to produce corner ice and ice skating when the icing temperature and wind speed are higher, and the icing surface is rougher. When the other conditions remain unchanged, the decrease in temperature, an increase in wind speed, or a rise in liquid water content all lead to an increase in the average thickness of icing and the volume of icing at the leading edge, with the effect of the wind speed on the two being 147.8% and 147.9%, the effect of the liquid water content on the two being 39.9% and 53.5%, and the effect of the temperature on the two being 24.6% and 13.2%. The study finds that the blade tip experiences the maximum displacement in both iced and non-iced states, although the positions of peak equivalent stress and strain vary. The above study will also provide references for the design of new wind turbine blades and the anti-icing maintenance of wind turbine generator sets.
Sulfonated Molecules and Their Latest Applications in the Field of Biomaterials: A Review
Authors: Akram Ambreen , Iqbal Mujahid , Yasin Aqeela , Zhang Kun , Li Jingan
Published: February 2024

This review provides an overview of the latest applications of sulfonated molecules in biomaterials. Sulfonation, a chemical modification process introducing sulfonic acid groups, enhances biomaterial properties. This review explores the effect of sulfonation and recent innovations in biomaterial applications. It covers hydrogels, scaffolds, and nanoparticles, emphasizing sulfonation’s unique advantages. The impact on cellular responses, including adhesion, proliferation, and differentiation, is discussed. This review also addresses sulfonated biomaterials’ role in regenerative medicine, drug delivery, and tissue engineering challenges. It also provides a small overview of the sources and features of marine-derived sulfonated molecules, emphasizing their potential roles in advancing scientific research. As a novel aspect, an unconventional complex, “traditional Chinese medicine” and its sulfonation method have come to the forefront after a thousand years of history. This article concludes with a reflection on current research and future avenues, highlighting sulfonation’s transformative potential in biomedicine.
The Mechanism of Resonant Amplification of One-Dimensional Detonation Propagating in a Non-Uniform Mixture
Authors: Lopato Alexander , Utkin Pavel
Published: February 2024

The propagation of detonation waves (i.e., supersonic combustion waves) in non-uniform gaseous mixtures has become a matter of interest over the past several years due to the development of rotating detonation engines. It was shown in a number of recent theoretical studies of one-dimensional pulsating detonation that perturbation of the parameters in front of the detonation wave can lead to a resonant amplification of intrinsic pulsations for a certain range of perturbation wavelengths. This work is dedicated to the clarification of the mechanism of this effect. One-dimensional reactive Euler equations with single-step Arrhenius kinetics were solved. Detonation propagation in a gas with sine waves in density was simulated in a shock-attached frame of reference. We carried out a series of simulations, varying the wavelength of the disturbances. We obtained a non-linear dependence of the amplitude of these pulsations on the wavelength of disturbances with resonant amplification for a certain range of wavelengths. The gain in velocity was about 25% of the Chapman–Jouguet velocity of the stable detonation wave. The effect is explained using the characteristic analysis in the x-t diagram. For the resonant case, we correlated the pulsation period with the time it takes for the C+ and C− characteristics to travel through the effective reaction zone. A similar pulsation mechanism is realized when a detonation wave propagates in a homogeneous medium.
A Eulerian Numerical Model to Predict the Enhancement Effect of the Gravity-Driven Motion Melting Process for Latent Thermal Energy Storage
Authors: Tian Shen , Tan Bolun , Lin Yuchen , Wang Tieying , Hu Kaiyong
Published: February 2024

Latent thermal energy storage (LTES) devices can efficiently store renewable energy in thermal form and guarantee a stable-temperature thermal energy supply. The gravity-driven motion melting (GDMM) process improves the overall melting rate for packaged phase-change material (PCM) by constructing an enhanced flow field in the liquid phase. However, due to the complex mechanisms involved in fluid–solid coupling and liquid–solid phase transition, numerical simulation studies that demonstrate physical details are necessary. In this study, a simplified numerical model based on the Eulerian method is proposed. We aimed to introduce a fluid deformation yield stress equation to the “solid phase” based on the Bingham fluid assumption. As a result, fluid–solid coupling and liquid–solid phase transition processes become continuously solvable. The proposed model is validated by the referenced experimental measurements. The enhanced performance of liquid-phase convection and the macroscopic settling of the “solid phase” are numerically analyzed. The results indicate that the enhanced liquid-phase fluidity allows for a stronger heat transfer process than natural convection for the pure liquid phase. The gravity-driven pressure difference is directly proportional to the vertical melting rate, which indicates the feasibility of controlling the pressure difference to improve the melting rate.
Transcriptional Profiling Reveals Key Regulatory Roles of the WUSCHEL-Related Homeobox Gene Family in Yellowhorn (Xanthoceras sorbifolia Bunge)
Authors: Zhang Wentao , Xie Xinyao , Le Linlin , Cao Fuliang
Published: February 2024

The WUSCHEL-related homeobox (WOX) gene family plays a crucial role in regulating embryonic development, organ formation, and stress resistance. Yellowhorn (Xanthoceras sorbifolia Bunge), a drought-resistant tree known for its oil production, lacks sufficient information regarding the WOX gene family. To understand the evolutionary mechanisms and potential functions of this gene family in yellowhorn, we conducted a comprehensive investigation on its expression patterns and evolutionary characteristics. Our analysis revealed the presence of nine XsWOX genes in the yellowhorn genome, which could be categorized into three distinct clades through a phylogenetic analysis. A chromosomal localization analysis indicated that these nine XsWOX genes were situated on six out of the fifteen chromosomes. An intra-species collinear analysis revealed only one pair of tandem duplicated genes within the XsWOX family. The promoter regions of the XsWOX family were found to contain responsive cis-acting elements associated with plant growth and development, stress responses, and hormone signaling. Moreover, an analysis of the gene expression profiles in different developmental stages of callus revealed significant expressions of XsWOX1, XsWOX4, and XsWOX5 in embryogenic callus and somatic embryo formation, suggesting that they have special roles in regulating yellowhorn’s somatic embryogenesis. Furthermore, the expression level of XsWOX5 indicated its potential involvement not only in organ formation but also in responding to low temperature, salt, and saline-alkali stresses. Overall, our findings lay a solid foundation for future in-depth studies on the functionality and evolution of XsWOX genes in yellowhorn.
The Impact of Aesthetic Expectations and Aesthetic Experiential Qualities on Tourist Satisfaction: A Case Study of the Zhangjiajie National Forest Park
Authors: Wen Ying , Luo Fen , Li Hao
Published: February 2024

Aesthetic expectations often constitute the primary focus in marketing nature-based tourist destinations. However, academic research has insufficiently explored the disparity between tourists’ aesthetic expectations and the actual aesthetic quality maintenance in shaping satisfaction. Employing the Expectation Confirmation Theory, this study utilized structural equation modeling techniques to analyze survey data (n = 446). It proposed and tested an Aesthetic Expectation Confirmation Model to examine the relationship between aesthetic expectations, experiential qualities, and tourist satisfaction in the Zhangjiajie National Forest Park. The empirical findings show that aesthetic expectations have a direct, negative impact on satisfaction, while aesthetic expectation confirmation has a positive direct impact on satisfaction. Moreover, aesthetic expectation confirmation also plays a mediating role in the influence of aesthetic expectations and experiential quality on satisfaction. Specifically, aesthetic expectations indirectly impact satisfaction negatively through aesthetic expectation confirmation, whereas aesthetic experiential qualities have a positive, indirect impact on satisfaction through the same process. These findings offer theoretical contributions to the literature on forest recreation aesthetics and hold practical significance for the planning and management of destination aesthetics.
Preparation and Properties of Soft-/Hard-Switchable Transparent Wood with 0 °C as a Boundary
Authors: Liu Yang , Zhang Yi , Guo Jianhui , Guo Gaiping , Li Cheng
Published: February 2024

Transparent wood has excellent optical and thermal properties and has great potential utilization value in energy-saving building materials, optoelectronic devices, and decorative materials. In this work, transparent wood with soft-/hard-switchable and shape recovery capabilities was prepared by introducing an epoxy-based polymer with a glass transition temperature of about 0 °C into the delignified wood template. The epoxy resin was well filled in the pore structure of the delignified wood, and the as-prepared wood exhibited excellent transparency; the optical transmittance and haze of the transparent wood with a thickness of 2.0 mm were approximately 70% and 95%, respectively. Because the glass transition temperature of the epoxy-based polymer was about 0 °C, the prepared transparent wood was rigid below 0 °C and flexible above °C; meanwhile, the transparent wood exhibited shape change and shape recovery properties. Incorporating optical transparency and soft-/hard-switchable ability into the transparent wood opens a new avenue for developing advanced functional wood-based materials.
Utilizing Comprehensive Criteria and Indicators for Post-Fire Forest Restoration in Spatial Decision Support Systems (SDSS)
Authors: Alayan Rahaf , Lakner Zoltán
Published: February 2024

Amidst the increasing frequency and severity of forest fires globally, the imperative of effective post-fire forest restoration has gained unprecedented significance. This study outlines a comprehensive approach to post-fire forest restoration and discusses its implementation through spatial decision-making systems. The methodology involves utilizing multi-criteria analysis (MCA) to identify and prioritize criteria based on their relative importance. This allows for the creation of easily assessable alternatives and their application to spatial maps, providing local officials with valuable information. To achieve optimal decision-making, the study utilized the Analytic Hierarchy Process (AHP) and the Decision-Making Trial and Evaluation Laboratory (DEMATEL) methods along with Spatial Decision Support Systems (SDSS) to generate a suitability map. The results highlight that 28% of the study area is well-suited for post-fire forest restoration, with 44% moderately appropriate, while 3% is deemed unsuitable for restoration until the end of 2023 due to severe soil loss or inherent geographical challenges.