bluuebunny/crossref_metadata_2025 huggingface dataset:
Motivation is not enough: A qualitative study of lung cancer screening uptake in Australia to inform future implementation
Authors: Dunlop Kate L. A. , Marshall Henry M. , Stone Emily , Sharman Ashleigh R. , Dodd Rachael H. , Rhee Joel J. , McCullough Sue , Rankin Nicole M.
Published: September 2022

Introduction

Participation in lung cancer screening (LCS) trials and real-world programs is low, with many people at high-risk for lung cancer opting out of baseline screening after registering interest. We aimed to identify the potential drivers of participation in LCS in the Australian setting, to inform future implementation.

Methods

Semi-structured telephone interviews were conducted with individuals at high-risk of lung cancer who were eligible for screening and who had either participated (‘screeners’) or declined to participate (‘decliners’) in the International Lung Screening Trial from two Australian sites. Interview guide development was informed by the Precaution Adoption Process Model. Interviews were audio-recorded, transcribed and analysed using the COM-B model of behaviour to explore capability, opportunity and motivation related to screening behaviour.

Results

Thirty-nine participants were interviewed (25 screeners; 14 decliners). Motivation to participate in screening was high in both groups driven by the lived experience of lung cancer and a belief that screening is valuable, however decliners unlike their screening counterparts reported low self-efficacy. Decliners in our study reported challenges in capability including ability to attend and in knowledge and understanding. Decliners also reported challenges related to physical and social opportunity, in particular location as a barrier and lack of family support to attend screening.

Conclusion

Our findings suggest that motivation alone may not be sufficient to change behaviour related to screening participation, unless capability and opportunity are also considered. Focusing strategies on barriers related to capability and opportunity such as online/telephone support, mobile screening programs and financial assistance for screeners may better enhance screening participation. Providing funding for clinicians to support individuals in decision-making and belief in self-efficacy may foster motivation. Targeting interventions that connect eligible individuals with the LCS program will be crucial for successful implementation.
An aesthetic of (re)appropriation: Remediating practices as history and identity in LA Rebellion film and hip hop sampling
Authors: Wilder S. A.
Published: September 2022

This article examines remediation practices as forms of Black creativity in films associated with the ‘LA Rebellion’ and in hip hop from its first two decades. As used here, remediation has two meanings. It stands for the use of prior media in subsequent works, be it the file footage incorporated by the UCLA-based filmmakers of the ‘LA Rebellion’ (the name given to Black filmmakers who studied and produced films between the late 1960s and 1980s), or the use of sampling and turntable-manipulated breakbeats that defines early hip hop. However, remediation is also used here for its potential as a corrective. Although postmodernity’s pastiche is discernible in the remediated elements of texts associated with these separate but contemporaneous movements, there is something specifically Black in the freely appropriated and repurposed prior creative work towards transformative ends. Beyond any postmodern effect, these practices reflect specific ideas related to politics, revolution and counter-ideological impulses opposed to the dominant white culture that surrounded these artists, and to which their texts respond. This transformative reuse – visual or aural – expresses what Foucault termed ‘counter-history’ and ‘counter-memory’ – revealing subversive texts that complicate and challenge white cultural and historical hegemony.
‘Doing that music which moves me’: A conversation with Bristol hip hop pioneer, Krissy Kriss
Authors: McNally James , Johnson Kriss ‘Krissy Kriss’
Published: September 2022

From the early-1980s, the arrival of hip hop in the UK city of Bristol created a wave of new possibilities for multiracial Bristolians. In the medium-term, this would help yield the music popularly termed ‘the Bristol Sound’, exemplified by post-hip hop performers like Tricky and Massive Attack – all of whom were part of the city’s early hip hop scene. More immediately, however, Bristol would become home to a vital hip hop party culture, centred on makeshift – and frequently illegal – parties thrown in warehouses, shebeens and small independent clubs in and around the city’s storied Black district, St. Paul’s. In this wide-ranging oral history conversation, which broadens the debate on Bristol hip hop and its diasporic sound-making, pioneering Bristol MC, Kriss ‘Krissy Kriss’ Johnson, discusses his memories and experiences of hip hop in the city. He provides fresh insights on diasporic Black identities in semi-rural contexts; the historic textures of teenage Black popular culture in Bristol in the 1970s–80s; the political realities of early-Thatcherism; the resurgence of British street racism in the 1970s; the psychogeography of Bristol neighbourhoods and historic change in St. Paul’s; the historically grounded appeals of hip hop culture as a site of affirmative teenage Black identity and possibility; the lived experience of Bristol’s DIY hip hop party culture. In doing this, Johnson offers a historically important Black perspective on a scene that has often been glossed by journalists and academics alike in terms of its utopian polyculturalism. By prioritizing his response as a young Black person in the historical particularities of his lived context, the conversation moves beyond the priorities of such accounts to provide a nuanced appreciation of Bristol’s hip hop movement in the city’s complex race and class geography. The account, moreover, recentres hip hop in the history of this party scene, which journalists have typically viewed from the prism of an overdetermined hybridity seen as peculiar to the city.
Biological Activities of Schiff Bases Incorporating Benzothiazole Moiety
Authors: Ratnakar Baraskar Archana , P. Sonawane Ratnamala , Kshirsagar Nilesh , Pathan Sultan
Published: September 2022

The functionalization of organic molecules with the Schiff bases having benzothiazole moiety has grown rapidly due to its multiple therapeutic and pharmacological properties. They have driven enormous studies on their stereochemistry, bioactivity and synthetic attempts. The benzothiazole moiety is infinitesimal but broadly used for industrial purposes and also exhibits a broad range of biological activities. Study carried out on Schiff bases having benzothiazole had well-known promising activities like antimicrobial, antimalarial, antifungal, antitubercular, antiviral, antitumor, analgesic, anti-inflammatory and many more. This review brings forward a systematic and comprehensive survey of the reactivity and biological properties associated with the Schiff bases-benzothiazole derivatives and their analogs.
Synthesis and Biological Evaluation of Biphenyl Derivatives of Hydrazine via Palladium Catalyzed Suzuki-Miyaura Coupling Reaction
Authors: Chauhan M.H. , Solanki N.L.
Published: September 2022

Generally, several methods for the construction of biphenyls, including Stille coupling, Gomberg-Bachmann reaction, Ullmann reaction and Suzuki-Miyaura cross-coupling are reported. In present research, considering the particularities of these methods and the characteristics of the target compounds by Suzuki-Miyaura cross-coupling reaction. To investigate the optimal conditions, a model reaction was performed using 1-bromo-4-iodobenzene and phenyl boronic acid under different conditions. The products were characterized by FT-IR, mass, 1H NMR and 13C NMR spectroscopy.
Energy Efficient Synthesis of various Benzodiazepin-2-ones using Microwave Synthesizer
Authors: K. Khatri Jasmin , R. Pednekar Suhas , S. Chaughule Ramesh
Published: September 2022

Benzodiazepine-2-one moiety consists of a seven-membered heterocyclic ring, a derivative of benzodiazepine group, that works in the central nervous system and used for a variety of medical conditions, such as anxiety, seizures and alcohol withdrawal. Microwave assisted synthesis of certain medically important benzodiazepin-2-ones was carried out using hexamine and ammonium chloride starting from 2-aminobenzophenones. Feasibility and optimization of the reaction conditions under closed vessel CEM microwave synthesizer provide the desired product with excellent yields (~90%), within minutes of focused microwave irradiation, without the use of catalyst, thereby, revealing the benefit of saving energy and time.
Teatro amador e (re)existência
Authors: Figueiredo Ricardo Carvalho de , Oliveira Júlia de Castro
Published: September 2022

O presente artigo traz à cena o Grupo de Teatro São Gonçalo do Bação para discutir as relações que envolvem a criação e formas de existência de um grupo de teatro amador em um contexto comunitário. Após uma pesquisa inicial para descobrir grupos amadores no Estado de Minas Gerais, elegemos o referido grupo para acompanhamento dos ensaios, conhecer mais de perto a comunidade na qual estava inserido e realizamos uma Entrevista Narrativa com o fundador e diretor do grupo, a fim de conhecermos os meandros da criação teatral e o processo de inserção na comunidade. Concluímos com essa pesquisa que grupos amadores (re)existem e realizam um trabalho artístico potente, inspirador e repleto de afetividade, sendo agentes culturais necessários para fortalecer o campo artístico e cultural no contexto do qual estão inseridos. Tensionam a política cultural local e nacional e são importantes fomentadores do teatro em lugares que há pouca, ou quase nenhuma manifestação artística. A força e a resistência de um grupo longevo demonstrou que, no coletivo, é possível existir e resistir ao tempo que amedronta e tolhe a criação artística.
Education Fair: Layanan Bimbingan Karier dalam Perencanaan Studi Lanjut Siswa di Tumbuh High School
Authors: Sari Ferra Puspito
Published: September 2022

Student problems related to planning for further studies require career guidance services from guidance and counseling teachers at schools. Tumbuh High School, through the Education Fair program, seeks to assist students in the process of planning further studies. This study aims to describe and analyze the application of education fair as a career guidance service in planning for further studies for Tumbuh High School students. This study uses descriptive qualitative research methods, data collection through interviews, observation, and documentation. The subjects in this study were school principals, guidance and counseling teachers, parents, and Tumbuh High School students who were involved in and affected by the education fair program. The results of this study indicate that the education fair held at Tumbuh High School begins with an in-depth assessment to determine the talents and interests of students, the selection of universities or partner institutions according to the results of the assessment, the implementation of the educational fair by partner institutions attended by students and their parents; and evaluation of implementation. Students are more mature in planning a career related to studies based on their talents and interests.
Pendidikan Kritis Mansour Fakih: Sudut Pandang Pendidikan Islam
Authors: Amri Mochammad Ja’far , Radino Radino
Published: September 2022

Education has a final orientation as a form of humanization, namely humanizing humans, and aims as a vehicle for liberation. One of the figures who brought this idea up was Mansour Fakih, a social activist who is aggressively voicing education from the point of view of the marginalized. This study uses qualitative research methods with the type of literature study. The results show that the idea of education with Mansour Fakih's critical paradigm can improve the domination structure which is considered inappropriate in the field of education by producing a critical perspective. A review of Islamic education can later have implications for education that eliminates aspects of class, humanist education, and critical ideas aligned with Islamic views. From these three concepts, it is hoped that education in Indonesia can be better in the future structurally and culturally so that it can become a vehicle for learning to think critically for the next generation of people who innovate with development.
New Diagnostic Criteria for Overmedication in Systemic Arterial Hypertension
Authors: Silva Ricardo Pereira , Rodrigues Henrique
Published: September 2022

Background

Guidelines on managing arterial blood pressure have begun to include lower targets, despite the risk for overmedication-induced hypotension. Because there is no consensus as to what constitutes overmedication in the treatment of hypertension, we conducted a study to develop relevant diagnostic criteria.

Methods

We used ambulatory monitoring during a 24-hour period to measure blood pressure in 567 patients with medication-controlled hypertension. We then divided this cohort into 3 groups. Group A (n = 413 [72.8%]) comprised patients in whom less than 10% of systolic blood pressure measurements were less than 100 mm Hg (no or mild hypotension). Group B (n = 154 [27.2%]) comprised patients in whom 10% or more of the measurements were less than 100 mm Hg, signifying overmedication. Group C comprised those patients in Group B in whom 20% or more of the measurements were less than 100 mm Hg (n = 74 [48.1%]; attributed to “accentuated” overmedication). Group C patients were prescribed significantly more antihypertensive drugs than were group A patients.

Results

Our findings support a 2-part definition of overmedication in hypertension treatment: (1) mild overmedication, in which 10% or more but less than 20% of systolic blood pressure measurements are less than 100 mm Hg in the awake state and less than 90 mm Hg during sleep; and (2) accentuated overmedication, characterized by 20% or more of valid systolic blood pressure measurements less than 100 mm Hg in the awake state and less than 90 mm Hg during sleep, during a 24-hour period.

Conclusion

We think this guidance will help to avoid overmedicating and consequences such as fainting and falls when systolic blood pressure is too low.
Znaczenie neutralności klimatycznej w systemie ochrony praw jednostki Republiki Federalnej Niemiec
Authors: Hałub-Kowalczyk Olga
Published: September 2022

Celem niniejszego artykułu jest analiza wyroku Federalnego Trybunału Konstytucyjnego (FTK) w Niemczech wydanego w marcu 2021 r., w którym Trybunał orzekł, że osiągnięcie neutralności klimatycznej jest nowym, konstytucyjnym obowiązkiem władz publicznych. Przesłankami podjęcia niniejszych badań stał się nie tylko fakt przełomowego charakteru tego orzeczenia, ale także jego spodziewany wpływ na kształtowanie się nowej linii orzeczniczej w sprawach środowiskowych, których liczba w państwach europejskich sukcesywnie rośnie. W ramach badań należy zweryfikować hipotezę badawczą, że najnowsze orzecznictwo FTK pozwala na przyjęcie założenia, że postępujący proces ekologizacji praw człowieka w niemieckim porządku konstytucyjnym prowadzi do wyewoluowania nowej grupy uprawnień związanych z osiągnięciem neutralności klimatycznej. Ze względu na doniosłą rolę orzecznictwa FTK niniejsze badania stanowią głos w dyskusji nad aktualnymi wyzwaniami, z którymi musi mierzyć się judykatura w obliczu konieczności implementacji Europejskiego Zielonego Ładu, a także rolą i znaczeniem neutralności klimatycznej jako nowej wartości konstytucyjnej. W badaniach posłużono się metodą dogmatycznoprawną, przeprowadzono również analizę wybranego orzecznictwa FTK oraz Europejskiego Trybunału Praw Człowieka. Niniejsze rozważania prowadzą do konkluzji, iż w najnowszym orzecznictwie poświęconym kwestiom klimatycznym FTK koncentruje się przede wszystkim na ocenie konstytucyjności celów regulacji i przedsięwziętych środków służących terminowemu osiągnięciu neutralności klimatycznej. Należy jednak uznać, że w ciągu najbliższych lat zakres odpowiedzialności władz publicznych znacząco się zwiększy. Nie można wykluczyć, że po 2030 r. FTK będzie musiał ponownie zmierzyć się z pytaniem już nie tylko o celowość działania władz, lecz także efektywność przyjętych rozwiązań. W ocenie autorki do tego czasu sądowa, progresywna wykładnia przepisów Ustawy zasadniczej będzie potwierdzeniem rosnącego znaczenia neutralności klimatycznej jako nowej wartości o konstytucyjnym znaczeniu.
Niepewność a pieniądz gotówkowy w okresie pandemii: przypadek Polski
Authors: Pietrucha Jacek , Gulewicz Michał
Published: September 2022

Wzrost podaży pieniądza gotówkowego jest jednym z najciekawszych zjawisk monetarnych ostatnich lat. Zwłaszcza okres pandemii COVID-19 cechował się skokowym wzrostem znaczenia pieniądza gotówkowego w obiegu. W artykule rozważa się, czy niepewność związana ze skutkami pandemii była źródłem zwiększonej podaży pieniądza gotówkowego. W celu pomiaru niepewności skonstruowano Wskaźnik Niepewności Pandemicznej oraz Wskaźnik Niepewności Gospodarczej za okres styczeń 2019 – grudzień 2021. Konstruując wskaźniki przyjęto, że poziom niepewności odczuwany przez gospodarstwa domowe oraz przedsiębiorstwa niefinansowe lepiej obrazują wyszukiwania haseł w wyszukiwarce internetowej aniżeli (jak to ma miejsce w przypadku innych mierników niepewności) publikacje prasowe lub wskaźniki rynków finansowych. Obydwa nowe wskaźniki wykazują związek z podażą pieniądza gotówkowego w Polsce w okresie pandemii, przy czym związek ten jest szczególnie silny w przypadku Wskaźnika Niepewności Pandemicznej. Zmiany podaży pieniądza gotówkowego w Polsce nie były związane z dynamiką sprzedaży detalicznej (wykluczyć zatem można zmiany popytu na pieniądz z motywu transakcyjnego). Znaczenia nie mają także rzeczywiste przypadki COVID-19 oraz wysokość stopy procentowej. Utrzymywanie rezerwy pieniądza gotówkowego jest wobec tego traktowane przez podmioty jako optymalna strategia w okresie wzrostu niepewności. Ta funkcja pieniądza gotówkowego stwarza nowy kontekst w dyskusjach dotyczących pełnej rezygnacji z pieniądza gotówkowego.
Lipschitz Chain Approximation of Metric Integral Currents
Authors: Goldhirsch Tommaso
Published: September 2022

Every integral current in a locally compact metric space
X
can be approximated by a Lipschitz chain with respect to the normal mass, provided that Lipschitz maps into
X
can be extended slightly.
Kant’s Account of Epistemic Normativity
Authors: Hadisi Reza
Published: September 2022

According to a common interpretation, most explicitly defended by Onora O’Neill and Patricia Kitcher, Kant held that epistemic obligations normatively depend on moral obligations. That is, were a rational agent not bound by any moral obligation, then she would not be bound by any epistemic obligation either. By contrast, in this paper, I argue that, according to Kant, some epistemic obligations are normatively independent from moral obligations, and are indeed normatively absolute. This view, which I call epistemicism, has two parts. First, it claims that in the absence of other kinds of obligations, rational agents would still be bound by these epistemic obligations, i. e., that the latter are normatively independent. Second, it claims that, no matter what other obligations are at stake, rational agents are bound by these epistemic obligations, i. e., the normativity of these epistemic obligations is absolute in that it cannot be undercut by any moral or other sort of obligation. The argument turns on an exploratory reading of Kant’s remarks in “What Is Orientation in Thinking?” (1786) about the maxim of “thinking for oneself” as the “supreme touchstone of truth”. In contrast to O’Neill and Kitcher, I argue that if we interpret this maxim as stating the unifying principle of theoretical and practical reason, then we must interpret it as stating an epistemic, and not merely practical imperative. This result, I argue, vindicates epistemicism and illuminates interesting lessons about Kant’s conception of the category of “epistemic” norms. Further, it helps us make headway with Kant’s enigmatic remarks about the unity of practical and theoretical reason in the Groundwork, the first and second Critiques, and the Lectures on Logic. On my proposal, principles of the practical and theoretical uses of reason are unified through a formal epistemic principle.
Heterozygous CDC73 mutation causing hyperparathyroidism in children and adolescents: a report of 2 cases
Authors: Blackburn James , Mulvey Ian , Nadar Ruchi , Dias Renuka P. , Saraff Vrinda , Senniappan Senthil
Published: September 2022

Objectives

Primary hyperparathyroidism (PHPT), whilst common in elderly populations, is rare in adolescents. Hereditary cases make up less than 10% of patients with PH. We report two patients with CDC73 mutation presenting in early adolescence.

Case presentation

Case 1: A 14-year-old patient was referred from an adolescent mental health unit with hypercalcaemia. Imaging revealed a parathyroid adenoma. Genetic testing of the patient showed a heterozygous deletion of CDC73. Case 2: A 10-year-old patient was admitted to the general paediatric ward with symptoms suggestive of hypercalcaemia. The patient was known to carry an autosomal dominant mutation of CDC73. Imaging of the parathyroid gland showed bilateral adenoma.

Conclusions

We present two patients with CDC73 defects, who both presented with symptoms of hypercalcaemia. The cases highlight the difference in paediatric populations with PHPT who are often symptomatic at the time of diagnosis when compared to adult patients.
The Roles of Social Media in Information Services: Systematic Review and Expert Scrutiny
Authors: Keshavarz Hamid , Norouzi Yaghoub , Shabani Ali
Published: September 2022

As useful tools in delivering information services, social media could create a wide range of opportunities and reduce communication costs significantly. The present study set out to initially identify the potential roles of social media in information services using a systematic review procedure. Using the meta-synthesis method, the identified roles were organized in a conceptual model and then prioritized through Shannon’s entropy technique. The results showed that the operational, financial, strategic, user-related, and informing roles ranked first to fifth, respectively. In the last step, the results of a survey of 30 experts active in online information services were analyzed using the weighted average method to be compared with the findings of the systematic review. The order of prioritization of the roles and indicators from the experts’ point of view showed financial, user-related, strategic, operational, and informing roles, respectively. The prioritization of roles in Shannon’s entropy method was similar to the results from the perspective of experts in terms of strategic and informing roles. However, experts have come to understand more about financial and user-related roles for social media. The only factor that had the greatest difference in ranks between Shannon’s entropy method and experts’ opinions survey was the operational role, which ranked first in Shannon’s entropy method and fourth in expert scrutiny. The present study is one of the first attempts to identify the possible roles of social media in information services that can be considered a pioneering research by related researchers.
Contextual Factors Affecting the Cooperation of Vietnamese Academic Libraries in Information Resource Sharing
Authors: Van Do Hung , Dorner Daniel G. , Calvert Philip
Published: September 2022

The research examines the contextual landscape of academic libraries in Vietnam with the intention of discovering and exploring the barriers and enablers of cooperation in information resource sharing. The aim of this research is to address the principal question of: what are the contextual factors affecting the cooperation of academic libraries in information resource sharing in Vietnam? The interpretive study employed a mixed-methods approach and its findings are based on the analysis of data gathered from key informant interviews (20 library directors) and surveys (145 librarians, 182 students, and 46 lecturers) from 20 universities, as well as from documentary evidence. The participants involved in this study include library directors, librarians, and information users. Data shows that there are contextual factors affecting the cooperation in information resource sharing in terms of policies, directors’ attitudes, cooperative culture, IT infrastructure, information resources, lack of standards, and inappropriate funding roles of professional associations. Based on the findings, a model for cooperation in information resource sharing was developed with the contextual factors. The outcome of this research provides a model which incorporates the contextual factors influencing information resource sharing among academic libraries in Vietnam. To that extent, it contributes to our knowledge of information resource sharing in general, especially in regard to developing countries and more specifically to Vietnam. An acknowledgment of these factors will encourage more academic libraries to collaborate in sharing information resources in order to meet the demands of information users.
Comparisons of the Economist Topics on Three Countries from 1991 Through 2016
Authors: Guo Shesen , Zhang Ganzhou
Published: September 2022

New topic modeling technique has been increasingly used in research of communication for quick discovery of latent topics that are spread across huge volumes of text. This work intends to analyze and compare the topics automatically generated by Latent Dirichlet Allocation (LDA). The data for building LDA model in this work is based on 38,124 articles published from 1991 through 2016 in one of the world’s most influential political and economic magazines, The Economist. The retrieved documents for generating topics are divided into three countries of the UK, the US, and China in order to observe topical differences between these ingroup or outgroup countries in The Economist coverage. The work analyzes interpretability, overall weight distributions, and historical changing patterns of the topics using LDA model diagnostics. It discusses the hot or increasing trends using regression coefficient. The work also tentatively explores the relationship between the media agenda and events.
Diamond-like carbon films for tribological modification of rubber
Authors: Liu Jiaqi , Yang Tao , Cao Huatang , Deng Qiaoyuan , Pan Changjiang , Wen Feng
Published: September 2022

The service conditions of rubber seals are primarily in the dynamic sliding state, with a high coefficient of friction, which can seriously compromise the equipment’s safety and the services’ lifespan. Diamond-like carbon (DLC) films have been the ideal candidate for tribological modification of rubber surfaces due to their excellent tribological properties over the last two decades. This field can be widely discussed as a hard film on soft substrates, where the challenge is the mismatch of mechanical properties, leading to the exfoliation of DLC films in friction. Early work developed the DLC films with a segment structure to solve this critical issue, illustrating the possibility of wear-resistant rubber. In recent years, researchers have paid attention to further increasing the coated rubber’s lifetime in friction, focusing on adhesion. These research achievements were reviewed on the aspects of structurization, adhesion, and doping in this article. It proposed an alternative direction of understanding the surface wear mechanism for designing wear-resistant DLC films on rubber.
Academic Libraries’ Sustainable Preservation and Conservation Practices
Authors: Rachman Yeni Budi , Ratnasari Wiwit
Published: September 2022

Studies on climate change and sustainability have been gaining interest within the global preservation and conservation communities. However, studies related to sustainability in library preservation and conservation, especially in academic libraries, are still limited. This study aims to determine current practices of sustainable library preservation and conservation in academic libraries. The findings of this study will serve as a starting point to obtaining a comprehensive understanding of how academic libraries are implementing climate change–responsible preservation and conservation programs. This study applies quantitative and descriptive approaches to collect data. A questionnaire was distributed to the top 200 universities in the Universitas Indonesia (UI) GreenMetric World University Rankings 2021. The results show that current practices of sustainable library preservation and conservation implemented at the majority of academic libraries relate to sustainable energy use. Although some areas still need to be developed (e.g., policy and regulation toward sustainable library preservation and conservation practices, alternative eco-friendly preservation and conservation materials, and waste management practices), the fact that academic libraries have implemented sustainable practices in preservation and conservation is noted as a positive finding, since it represents success in universities’ efforts to address the climate change issue.
Back to School Amidst COVID-19 Impacts: A Perspective Report
Authors: Grover Sanya , Johal Shubhreet , Kyrychenko Polina , Leenus Selvin , Sabac Denise , Soliman Peter
Published: September 2022

Although the merits of in person learning outweigh those of virtual learning for elementary students, online learning is often implemented in response to rising cases of COVID-19. As such, the significant number of barriers to remote learning must be addressed in order to promote effective and health conscious learning for students during the pandemic. Students have been facing challenges with self-regulation, work management and lack of socio-emotional connections while teachers have been facing obstacles related to effectively using technology to deliver content and engage students. Parents have struggled to understand and fulfill their role supporting their children within the online school environment. Considering the perspectives presented in the literature, efforts should be made to promote connectedness and support for families during this difficult time. A resource toolkit is suggested for caregivers of children enrolled in online school to implement strategies at home to assist their children in their education.
Peripheral Auditory Nerve Impairment in a Mouse Model of Syndromic Autism
Authors: McChesney Nathan , Barth Jeremy L. , Rumschlag Jeffrey A. , Tan Junying , Harrington Adam J. , Noble Kenyaria V. , McClaskey Carolyn M. , Elvis Phillip , Vaena Silvia G. , Romeo Martin J. , Harris Kelly C. , Cowan Christopher W. , Lang Hainan
Published: September 2022

Dysfunction of the peripheral auditory nerve (AN) contributes to dynamic changes throughout the central auditory system, resulting in abnormal auditory processing, including hypersensitivity. Altered sound sensitivity is frequently observed in autism spectrum disorder (ASD), suggesting that AN deficits and changes in auditory information processing may contribute to ASD-associated symptoms, including social communication deficits and hyperacusis. The MEF2C transcription factor is associated with risk for several neurodevelopmental disorders, and mutations or deletions ofMEF2Cproduce a haploinsufficiency syndrome characterized by ASD, language, and cognitive deficits. A mouse model of this syndromic ASD (Mef2c-Het) recapitulates many of theMEF2Chaploinsufficiency syndrome-linked behaviors, including communication deficits. We show here thatMef2c-Het mice of both sexes exhibit functional impairment of the peripheral AN and a modest reduction in hearing sensitivity. We find that MEF2C is expressed during development in multiple AN and cochlear cell types; and inMef2c-Het mice, we observe multiple cellular and molecular alterations associated with the AN, including abnormal myelination, neuronal degeneration, neuronal mitochondria dysfunction, and increased macrophage activation and cochlear inflammation. These results reveal the importance of MEF2C function in inner ear development and function and the engagement of immune cells and other non-neuronal cells, which suggests that microglia/macrophages and other non-neuronal cells might contribute, directly or indirectly, to AN dysfunction and ASD-related phenotypes. Finally, our study establishes a comprehensive approach for characterizing AN function at the physiological, cellular, and molecular levels in mice, which can be applied to animal models with a wide range of human auditory processing impairments.

SIGNIFICANCE STATEMENTThis is the first report of peripheral auditory nerve (AN) impairment in a mouse model of humanMEF2Chaploinsufficiency syndrome that has well-characterized ASD-related behaviors, including communication deficits, hyperactivity, repetitive behavior, and social deficits. We identify multiple underlying cellular, subcellular, and molecular abnormalities that may contribute to peripheral AN impairment. Our findings also highlight the important roles of immune cells (e.g., cochlear macrophages) and other non-neuronal elements (e.g., glial cells and cells in the stria vascularis) in auditory impairment in ASD. The methodological significance of the study is the establishment of a comprehensive approach for evaluating peripheral AN function and impact of peripheral AN deficits with minimal hearing loss.
FAO, FIDA, OMS, PMA Y UNICEF. EL ESTADO DE LA SEGURIDAD ALIMENTARIA Y LA NUTRICIÓN EN EL MUNDO 2019. PROTEGERSE FRENTE A LA DESACELERACIÓN Y EL DEBILITAMIENTO DE LA ECONOMÍA (PRIMERA EDICIÓN. ROMA: FAO, 2019)
Authors: Salinas Ramírez Nicolas , Martínez Patricio Gustavo , Uribe Cortez Jaime , Romero Santos Rosita Deny , García Lopez Elvis , Soto Martín Juan José Guadalupe , Castillo Martínez Antonio , Gutiérrez Ramírez Adriana
Published: September 2022

El estudio denominado El estado de la seguridad alimentaria y la nutrición en el mundo: Protegerse frente a la desaceleración es una producción de la Organización de las Naciones Unidad para la Alimentación y la Agricultura del año 2019, la cual presenta una brillante exposición sobre las condiciones que guarda la alimentación en el mundo. En el libro se muestra la estructura capitular que permite observar su conformación general. A lo largo de este texto se desarrollan las temáticas más relevantes.
Planificación estratégica para el diseño curricular universitario. Una propuesta metodológica
Authors: Barquero D’Avanzo Ana Milena
Published: September 2022

El presente artículo tiene como propósito contribuir con la modernización de la enseñanza superior por medio de la transformación y la renovación del currículo orientado a la excelencia académica, la generación, innovación y transferencia del conocimiento, la equidad e inclusión social, la globalización e internacionalización del conocimiento.Este estudio se realizó en el marco de una investigación educativa con un enfoque cualitativo. Con el objetivo de analizar el diseño curricular en la Sede del Atlántico de la Universidad de Costa Rica. Uno de los resultados de esta investigación es una estrategia de planificación para el diseño curricular universitario, desarrollada en la Universidad de Costa Rica para la Sede del Atlántico.Este trabajo incluye un referente cognoscente sobre estrategias de planificación y el diseño curricular universitario. Al mismo tiempo que evidencia la relación existente entre los términos educación y currículo. Producto del proceso de indagación se propone una estrategia de planificación para innovar, renovar y / o redefinir el diseño curricular de la Sede del Atlántico en términos de formación, investigación y proyección social.
An improved ultra-high performance liquid chromatography-tandem mass spectrometry method determining hispidulin and homoplantaginin in rat plasma and associated pharmacokinetic studies
Authors: Zhang En , Chen Junying , Li Xia , Luo Lvqi , Ma Yizhe , Zhang Qingwei , Wang Xianqin
Published: September 2022

Flavonoids are the most abundant components in Salvia plebeia, with significant pharmacological antioxidant and hepatoprotective properties. Hispidulin and homoplantaginin are the main flavonoid components in S. Plebeia. In this study, we established an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to determine hispidulin and homoplantaginin in rat plasma samples, which were precipitated using acetonitrile-methanol (9:1, v/v). We used a UPLC HSS T3 (100 mm × 2.1 mm, 1.7 μm diameter) chromatographic column, an acetonitrile-water (containing 0.1% formic acid) mobile phase, and a gradient elution flow rate of 0.4 mL min−1 in an elution time of 4 min. We used electrospray ionization (ESI) detection in positive ion mode, and multiple reaction monitoring mode (MRM) for quantitative analysis: m/z 301 → 286 for hispidulin, m/z 463 → 301 for homoplantaginin, and m/z 465 → 303 for internal standard (IS). In pharmacokinetic studies, 24 rats were orally administered hispidulin and homoplantaginin (5 mg kg−1) and received sublingual intravenous injections (1 mg kg−1) at two different doses, four groups with six rats/group. Differences in hispidulin and homoplantaginin pharmacokinetics in rat plasma were evaluated. The calibration curve showed good linearity in the 0.5–1,000 ng mL−1 range, with r > 0.99. Precision, accuracy, recovery, matrix effects, and stability results all met standard biological sample detection requirements. Our pharmacokinetic studies showed hispidulin bioavailability was much higher than homoplantaginin at 17.8% and 0.1%, respectively.
Nilai-Nilai Pernikahan Ideal Perspektif Hadis dalam Film Twivortiare
Authors: Awaliyah Robiah
Published: September 2022

Building an ideal marriage is an issue that often occurs in society. This study aims to discuss the ideal marriage in the film Twivortiare from a hadith perspective. This research is a qualitative type using successive thematic, takhrij and syarah approaches and the living sunnah method is used to find the ideal marriage values in the Twivortiare film. The results and discussion in this article show that in the Twivortiare film there are ideal marriage values from a hadith perspective such as treating spouses well as contained in Musnad Ahmad Number 7095, accepting and complementing each other as contained in Sahih Muslim Number 2672, and maintaining intimacy. with a partner as exemplified by Rasulullah in Sahih Bukhari Number 288. This study concludes that in the Twivortiare film there are ideal marriage values that can be a solution so that marriages avoid actions that lead to disharmony and divorce. This study recommends that every married couple can instill the value of an ideal marriage even though it is through the meaning of the film.
„Zielona” rewitalizacja starówki w Gorlicach
Authors:   Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych, Instytut Nauk Rolniczych, Ochrony i Kształtowania Środowiska, Pracownia Architektury Krajobrazu, Polska, Gargała-Polar Marta , Gajdek Agata ,   Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych, Instytut Nauk Rolniczych, Ochrony i Kształtowania Środowiska, Pracownia Architektury Krajobrazu, Polska, Kaspruk Ilona ,   Gorlice, Pracownia Architektury Krajobrazu Ilona Kaspruk, Polska
Published: September 2022

In the era of climate change and the need for closer contact with nature for the population of urban agglomerations, modern cities modernize their development strategies, designing new and supplementing existing urban layouts with plant forms. A good solution to the current urban problems is to create spaces that are filled with greenery, while maintaining the value of the existing historical values. The aim of the study is to present the possibility of supplementing the existing composition of the historic town square with various plant forms, on the example of the Gorlice. The original concept of creating a sustainable space in the city center, accessible to residents and tourists, refers to the current trends of greening and unsealing impermeable city squares.
Wypas koni huculskich jako forma zrównoważonego rolnictwa w rejonie Bieszczadów
Authors:   Zakład Produkcji Zwierzęcej i Oceny Produktów Drobiarskich, Kolegium Nauk Przyrodniczych, Uniwersytet Rzeszowski, Polska, Topczewska Jadwiga , Krupa Wanda ,   Zakład Behawioru i Dobrostanu Zwierząt, Wydział Nauk o Zwierzętach i Biogospodarki, Uniwersytet Przyrodniczy w Lublinie, Polska, Krempa Amanda ,   SKN Animal Equus, Uniwersytet Rzeszowski, Polska
Published: September 2022

The aim of the study was to analyze the grazing of Hucul horses as an element of sustainable agriculture in NATURA 2000-protected areas. The condition of the horses and the grazing load were assessed, as well as the number of birds present and foraging. A load of up to 10 DPJ, resulting from the implementation of agri-environmental programs, appears to be adequate both in terms of counteracting succession and protecting against degradation. The results confirm the positive impact of grazing on habitat species diversity, contributing to the preservation of nesting and foraging sites for birds.
A novel damage index extracted from frequency response of cracked Timoshenko beam subjected to moving harmonic load
Authors: Khiem Nguyen Tien , Hang Phi Thi
Published: September 2022

In this paper, there is proposed a novel damage index extracted from frequency response of cracked Timoshenko beam under moving harmonic load using the so-called Modal Assurance Criterion (MAC) concept. First, frequency response of a cracked Timoshenko beam subjected to harmonic force moving on the beam with constant speed is obtained in an analytical expression. Then, a scalar characteristic like the coherence between the frequency responses of intact and cracked beams is determined and called herein Spectral Assurance Criterion (SAC). Such designed criterion is dependent upon crack parameters (location and depth), the load frequency and speed as well as position on beam where the responses have been measured. Numerical analysis shows that SAC is much more sensitive to crack than natural frequencies and can be used as a novel damage index for crack detection in beam using moving load. The effect of moving load frequency and speed has been also examined with the aim to have got an indicator most adequate for the crack detection problem.
Morphological and molecular characterisations of \(\textit{Scutellonema brachyurum}\) (Steiner, 1938) Andrassy, 1958 from the western highlands, Vietnam
Authors: Phap Trinh Quang , Nguyen Thi Duyen , Linh Le Thi Mai , Tien Nguyen Huu
Published: September 2022

The genus Scutellonema consists of about 50 species that are phytophagous (ecto- and partially endo-parasites). Among species of the genus Scutellonema, Scutellonema brachyurum was reported to be one of the three most damaging ones, causing serious symptoms to numerous host plants worldwide. In the past, Scutellonema species have been described using morphological and morphometric characterizations, however, cryptic species have been proven to exist in the genus. Therefore, molecular data is clearly needed in identifying Scutellonema species to ensure correct outcomes. In this study, we provide morphological and molecular characterizations of S. brachyurum recovered from the rhizosphere of Vietnamese ginseng for the first time. Morphological comparison and PCA analysis indicated that our nematode population is closer to S. brachyurum type B, however, molecular data of D2-D3 of 28S rRNA region indicates that the Vietnamese population of S. brachyurum belongs to type A. Our study also provides the 18S rRNA sequence of S. brachyurum for the first time in GenBank (only 18S sequences of Scutellonema bradys are available in the genus Scutellonema before this study). Phylogenetic trees based on 18S and D2-D3 sequences are also provided for a better understanding of the relationships between Scutellonema species. Besides, this species was found in association with tuber rot symptom of the host plant, implying potential pathogenicity, and thus, more attention needs to be paid to better understand this pest.
A taxonomic update 20 years after the book release “The amphibians and reptiles of a lowland forest reserve in Vietnam”- Ho Ke Go: implications for conservation
Authors: Ziegler Thomas , Ong An Vinh , Hoang Quang Xuan , Pham Cuong The , Nguyen Truong Quang
Published: September 2022

We provide a taxonomic update of the herpetofauna of the Ke Go Nature Reserve, Ha Tinh province, north-central Vietnam, 20 years after the book release “The amphibians and reptiles of a lowland forest reserve in Vietnam”. In this work, Ziegler (2002) recorded 31 amphibians and 57 reptiles. Since then 30 changes in the generic assignment of species took place, five of six unnamed identifications could be solved, three unclear identifications clarified, and 12 taxa were newly described. This review has not only significance for updated names of taxa listed in the book and follow-up papers, but also for conservation. Reviews and descriptions resulted in taxa with more restricted distributions, such as, e.g., Gekko reevesii (formerly G. gekko, listed on CITES Appendix II and in the Red Data Book) and Pelodiscus variegatus (formerly P. sinensis, listed in the IUCN Red List, and split off taxa on CITES Appendix II). More species meanwhile are listed as threatened (in total 25), and for some of them, the threat status has increased in the meantime. In addition to the 88 amphibian and reptile species recorded by Ziegler (2002), three further records are added herein, resulting in 91 proven species. There is also evidence for the occurrence of 10 further reptile species, which would increase the herpetofauna list to 101. One half of these 10 additional reptile species are threatened which would increase the threatened herpetofauna to 30 species. This highlights the need for improved conservation, both concerning the official protection status of so far not yet officially listed threatened taxa and IUCN’s One Plan Approach conservation, covering in situ conservation measures and ex situ conservation breeding approaches. Representing one of Vietnam’s last remaining lowland forests with a high biodiversity and conservation value, the Ke Go Nature Reserve highly deserves reinforced conservation measures.