bluuebunny/crossref_metadata_2025 huggingface dataset:
Extensive Modeling of Peculiar Hydration in Fine Micro-Pore Structures Applicable to Integrated Thermodynamic Analysis for Portland Cement
Authors: Kinomura Koji , Ishida Tetsuya
Published: May 2019

Although applications of low water-to-cement ratio mixtures to practical structures have been increasing to enhance seismic resistance and long-term durability in recent years, it was experimentally observed that such a mixture causes peculiar hydration under long-term normal or high temperature curing. On the other hand, excessive hydration was revealed in the analysis using the original model, compared with the experiment in such an environment, because un-hydrated cement particles and existing condensed water reacted more significantly in the model. This study aims to enhance the integrated multiscale thermodynamic analysis, which is able to predict structural behavior in various conditions in a unified approach, by incorporating recent technical evolutions for its reverification and extending the original model to resolve the above peculiar concerns. Hence, the extensive modeling of continuous hydration considering spatial condensed water in fine micro-pore structures was proposed. Further, coupling of the integrated analysis with the extensive model was conducted, providing good agreement with time-dependent deformation experiments at different temperatures. Eventually, the validity and practical benefit of this study were demonstrated.
Extraction of Zero-Point Energy from the Vacuum: Assessment of Stochastic Electrodynamics-Based Approach as Compared to Other Methods
Authors: Moddel Garret , Dmitriyeva Olga
Published: May 2019

In research articles and patents several methods have been proposed for the extraction of zero-point energy from the vacuum. None of the proposals have been reliably demonstrated, yet they remain largely unchallenged. In this paper the underlying thermodynamics principles of equilibrium, detailed balance, and conservation laws are presented for zero-point energy extraction. The proposed methods are separated into three classes: nonlinear processing of the zero-point field, mechanical extraction using Casimir cavities, and the pumping of atoms through Casimir cavities. The first two approaches are shown to violate thermodynamics principles, and therefore appear not to be feasible, no matter how innovative their execution. The third approach, based upon stochastic electrodynamics, does not appear to violate these principles, but may face other obstacles. Initial experimental results are tantalizing but, given the lower than expected power output, inconclusive.
Identification of Crucial Candidate Genes and Pathways in Glioblastoma Multiform by Bioinformatics Analysis
Authors: Alshabi Ali Mohamed , Vastrad Basavaraj , Shaikh Ibrahim Ahmed , Vastrad Chanabasayya
Published: May 2019

The present study aimed to investigate the molecular mechanisms underlying glioblastoma multiform (GBM) and its biomarkers. The differentially expressed genes (DEGs) were diagnosed using the limma software package. The ToppGene (ToppFun) was used to perform pathway and Gene Ontology (GO) enrichment analysis of the DEGs. Protein-protein interaction (PPI) networks, extracted modules, miRNA-target genes regulatory network and TF-target genes regulatory network were used to obtain insight into the actions of DEGs. Survival analysis for DEGs was carried out. A total of 590 DEGs, including 243 up regulated and 347 down regulated genes, were diagnosed between scrambled shRNA expression and Lin7A knock down. The up-regulated genes were enriched in ribosome, mitochondrial translation termination, translation, and peptide biosynthetic process. The down-regulated genes were enriched in focal adhesion, VEGFR3 signaling in lymphatic endothelium, extracellular matrix organization, and extracellular matrix. The current study screened the genes in the PPI network, extracted modules, miRNA-target genes regulatory network, and TF-target genes regulatory network with higher degrees as hub genes, which included NPM1, CUL4A, YIPF1, SHC1, AKT1, VLDLR, RPL14, P3H2, DTNA, FAM126B, RPL34, and MYL5. Survival analysis indicated that the high expression of RPL36A and MRPL35 were predicting longer survival of GBM, while high expression of AP1S1 and AKAP12 were predicting shorter survival of GBM. High expression of RPL36A and AP1S1 were associated with pathogenesis of GBM, while low expression of ALPL was associated with pathogenesis of GBM. In conclusion, the current study diagnosed DEGs between scrambled shRNA expression and Lin7A knock down samples, which could improve our understanding of the molecular mechanisms in the progression of GBM, and these crucial as well as new diagnostic markers might be used as therapeutic targets for GBM.
Rapid Profiling of Soybean Aromatic Compounds Using Electronic Nose
Authors: Ravi Ramasamy , Taheri Ali , Khandekar Durga , Millas Reneth
Published: May 2019

Soybean (Glycine max (L.)) is the world’s most important seed legume, which contributes to 25% of global edible oil, and about two-thirds of the world’s protein concentrate for livestock feeding. One of the factors that limit soybean’s utilization as a major source of protein for humans is its characteristic soy flavor. This off-flavor can be attributed to the presence of various chemicals such as phenols, aldehydes, ketones, furans, alcohols, and amines. In addition, these flavor compounds interact with protein and cause the formation of new off-flavors. Hence, studying the chemical profile of soybean seeds is an important step in understanding how different chemical classes interact and contribute to the overall flavor profile of the crop. In our study, we utilized the HERCALES Fast Gas Chromatography (GC) electronic nose for identification and characterization of different volatile compounds in five high-yielding soybean varieties, and studied their association with off-flavors. With aroma profiling and chemical characterization, we aim to determine the quantity and quality of volatile compounds in these soybean varieties and understand their effect on the flavor profiles. The study could help to understand soybean flavor characteristics, which in turn could increase soybean use and enhance profitability.
The Advances in Biomedical Applications of Carbon Nanotubes
Authors: Saliev Timur
Published: May 2019

Unique chemical, physical, and biological features of carbon nanotubes make them an ideal candidate for myriad applications in industry and biomedicine. Carbon nanotubes have excellent electrical and thermal conductivity, high biocompatibility, flexibility, resistance to corrosion, nano-size, and a high surface area, which can be tailored and functionalized on demand. This review discusses the progress and main fields of bio-medical applications of carbon nanotubes based on recently-published reports. It encompasses the synthesis of carbon nanotubes and their application for bio-sensing, cancer treatment, hyperthermia induction, antibacterial therapy, and tissue engineering. Other areas of carbon nanotube applications were out of the scope of this review. Special attention has been paid to the problem of the toxicity of carbon nanotubes.
Integrin Regulation of CAF Differentiation and Function
Authors: DiPersio C. Michael , Van De Water Livingston
Published: May 2019

Extensive remodeling of the extracellular matrix, together with paracrine communication between tumor cells and stromal cells, contribute to an “activated” tumor microenvironment that supports malignant growth and progression. These stromal cells include inflammatory cells, endothelial cells, and cancer-associated fibroblasts (CAFs). Integrins are expressed on all tumor and stromal cell types where they regulate both cell adhesion and bidirectional signal transduction across the cell membrane. In this capacity, integrins control pro-tumorigenic cell autonomous functions such as growth and survival, as well as paracrine crosstalk between tumor cells and stromal cells. The myofibroblast-like properties of cancer-associated fibroblasts (CAFs), such as robust contractility and extracellular matrix (ECM) deposition, allow them to generate both chemical and mechanical signals that support invasive tumor growth. In this review, we discuss the roles of integrins in regulating the ability of CAFs to generate and respond to extracellular cues in the tumor microenvironment. Since functions of specific integrins in CAFs are only beginning to emerge, we take advantage of a more extensive literature on how integrins regulate wound myofibroblast differentiation and function, as some of these integrin functions are likely to extrapolate to CAFs within the tumor microenvironment. In addition, we discuss the roles that integrins play in controlling paracrine signals that emanate from epithelial/tumor cells to stimulate fibroblasts/CAFs.
Malignant Pheochromocytomas/Paragangliomas and Ectopic Hormonal Secretion: A Case Series and Review of the Literature
Authors: Angelousi Anna , Peppa Melpomeni , Chrisoulidou Alexandra , Alexandraki Krystallenia , Berthon Annabel , Faucz Fabio Rueda , Kassi Eva , Kaltsas Gregory
Published: May 2019

Malignant pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine neoplasms defined by the presence of distant metastases. There is currently a relatively paucity of data regarding the natural history of PCs/PGLs and the optimal approach to their treatment. We retrospectively analyzed the clinical, biochemical, imaging, genetic and histopathological characteristics of fourteen patients with metastatic PCs/PGLs diagnosed over 15 years, along with their response to treatment. Patients were followed-up for a median of six years (range: 1–14 years). Six patients had synchronous metastases and the remaining developed metastases after a median of four years (range 2–10 years). Genetic analysis of seven patients revealed that three harbored succinate dehydrogenase subunit B/D gene (SDHB/D) mutations. Hormonal hypersecretion occurred in 70% of patients; normetanephrine, either alone or with other concomitant hormones, was the most frequent secretory component. Patients were administered multiple first and subsequent treatments including surgery (n = 12), chemotherapy (n = 7), radionuclide therapy (n = 2) and radiopeptides (n = 5). Seven patients had stable disease, four had progressive disease and three died. Ectopic hormonal secretion is rare and commonly encountered in benign PCs. Ectopic secretion of interleukin-6 in one of our patients, prompted a literature review of ectopic hormonal secretion, particularly from metastatic PCs/PGLs. Only four cases of metastatic PC/PGLs with confirmed ectopic secretion of hormones or peptides have been described so far.
Wastewater Treatment by Catalytic Wet Peroxidation Using Nano Gold-Based Catalysts: A Review
Authors: Rodrigues Carmen S.D. , Silva Ricardo M. , Carabineiro Sónia A.C. , Maldonado-Hódar F.J. , Madeira Luís M.
Published: May 2019

Nowadays, there is an increasing interest in the development of promising, efficient, and environmentally friendly wastewater treatment technologies. Among them are the advanced oxidation processes (AOPs), in particular, catalytic wet peroxidation (CWPO), assisted or not by radiation. One of the challenges for the industrial application of this process is the development of stable and efficient catalysts, without leaching of the metal to the aqueous phase during the treatment. Gold catalysts, in particular, have attracted much attention from researchers because they show these characteristics. Recently, numerous studies have been reported in the literature regarding the preparation of gold catalysts supported on various supports and testing their catalytic performance in the treatment of real wastewaters or model pollutants by CWPO. This review summarizes this research; the properties of such catalysts and their expected effects on the overall efficiency of the CWPO process, together with a description of the effect of operational variables (such as pH, temperature, oxidant concentration, catalyst, and gold content). In addition, an overview is given of the main technical issues of this process aiming at its industrial application, namely the possibility of using the catalyst in continuous flow reactors. Such considerations will provide useful information for a faster and more effective analysis and optimization of the CWPO process.
NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β–NDRG2–PP2A Complex Formation
Authors: Park Soojong , Han Hyun-Tak , Oh Sang-Seok , Kim Dong Hyeok , Jeong Jin-Woo , Lee Ki Won , Kim Minju , Lim Jong Seok , Cho Yong Yeon , Hwangbo Cheol , Yoo Jiyun , Kim Kwang Dong
Published: May 2019

N-Myc downstream-regulated gene 2 (NDRG2) was characterized as a tumor suppressor, inducing anti-metastatic and anti-proliferative effects in several tumor cells. However, NDRG2 functions on anticancer drug sensitivity, and its molecular mechanisms are yet to be fully investigated. In this study, we investigated the mechanism of NDRG2-induced sensitization to As2O3 in the U937 cell line, which is one of the most frequently used cells in the field of resistance to As2O3. NDRG2-overexpressing U937 cells (U937-NDRG2) showed a higher sensitivity to As2O3 than mock control U937 cell (U937-Mock). The higher sensitivity to As2O3 in U937-NDRG2 was associated with Mcl-1 degradation through glycogen synthase kinase 3β (GSK3β) activation. Inhibitory phosphorylation of GSK3β was significantly reduced in U937-NDRG2, and the reduction was diminished by okadaic acid, a protein phosphatase inhibitor. NDRG2 mediated the interaction between GSK3β and protein phosphatase 2A (PP2A), inducing dephosphorylation of GSK3β at S9 by PP2A. Although the C-terminal deletion mutant of NDRG2 (ΔC NDRG2), which could not interact with PP2A, interacted with GSK3β, the mutant failed to dephosphorylate GSK3β at S9 and increased sensitivity to As2O3. Our findings suggest that NDRG2 is a kind of adaptor protein mediating the interaction between GSK3β and PP2A, inducing GSK3β activation through dephosphorylation at S9 by PP2A, which increases sensitivity to As2O3 in U937 cells.
Multi-Path Dilated Residual Network for Nuclei Segmentation and Detection
Authors: Wang Eric Ke , Zhang Xun , Pan Leyun , Cheng Caixia , Dimitrakopoulou-Strauss Antonia , Li Yueping , Zhe Nie
Published: May 2019

As a typical biomedical detection task, nuclei detection has been widely used in human health management, disease diagnosis and other fields. However, the task of cell detection in microscopic images is still challenging because the nuclei are commonly small and dense with many overlapping nuclei in the images. In order to detect nuclei, the most important key step is to segment the cell targets accurately. Based on Mask RCNN model, we designed a multi-path dilated residual network, and realized a network structure to segment and detect dense small objects, and effectively solved the problem of information loss of small objects in deep neural network. The experimental results on two typical nuclear segmentation data sets show that our model has better recognition and segmentation capability for dense small targets.
Antifungal Starch–Gellan Edible Coatings with Thyme Essential Oil for the Postharvest Preservation of Apple and Persimmon
Authors: Sapper Mayra , Palou Lluís , Pérez-Gago María B. , Chiralt Amparo
Published: May 2019

Starch–gellan (80:20) coating formulations were applied to apples and persimmons to analyse their effectiveness controlling the weight loss, respiration rate, fruit firmness, and fungal decay during postharvest. Thyme essential oil (EO) was incorporated (0.25 and 0.5 g per g of polymer) directly or encapsulated in lecithin to enhance antifungal action. Coatings did not reduce weight loss or firmness changes in apples, but they prevented water loss in persimmons. In contrast, no significant effect of the coatings was observed on the respiration rates and the respiration quotient of persimmons, whereas the respiration rates and quotient was increased in apples. On the other hand, the coatings without lecithin reduced the incidence and severity of black spot caused by Alternaria alternata in persimmons, regardless of the content of essential oil. Likewise, these reduced the severity of gray mold caused by Botrytis cinerea in apples. No positive effect of lecithin in coatings was observed on the postharvest quality and decay in either apples or persimmons, nor did EO exert antifungal action despite its proven effectiveness in in vitro tests.
A New Crop Spectral Signatures Database Interactive Tool (CSSIT)
Authors: Awad Mohamad M. , Alawar Bassem , Jbeily Rana
Published: May 2019

In many countries, commodities provided by the agriculture sector play an important role in the economy. Securing food is one aspect of this role, which can be achieved when the decision makers are supported by tools. The need for cheap, fast, and accurate tools with high temporal resolution and global coverage has encouraged the decision makers to use remote sensing technologies. Field spectroradiometer with high spectral resolution can substantially improve crop mapping by reducing similarities between different crop types that have similar ecological conditions. This is done by recording fine details of the crop interaction with sunlight. These details can increase the same crop recognition even with the variation in the crop chemistry and structure. This paper presents a new spectral signatures database interactive tool (CSSIT) for the major crops in the Eastern Mediterranean Basin such as wheat and potato. The CSSIT’s database combines different data such as spectral signatures for different periods of crop growth stages and many physical and chemical parameters for crops such as leaf area index (LAI) and chlorophyll-a content (CHC). In addition, the CSSIT includes functions for calculating indices from spectral signatures for a specific crop and user interactive dialog boxes for displaying spectral signatures of a specific crop at a specific period of time.
Data for Fish Stock Assessment Obtained from the CMSY Algorithm for all Global FAO Datasets
Authors: Hélias Arnaud
Published: May 2019

Assessing the state of fish stocks requires the determination of descriptors. They correspond to the absolute and relative (to the carrying capacity of the habitat) fish biomasses in the ecosystem, and the absolute and relative (to the intrinsic growth rate of the population) fishing mortality resulting from catches. This allows, among other things, to compare the catch with the maximum sustainability yield. Some fish stocks are well described and monitored, but for many data-limited stocks, catch time series are remaining the only source of data. Recently, an algorithm (CMSY) has been proposed, allowing an estimation of stock assessment variables from catch and resilience. In this paper, we provide stock reference points for all global fisheries reported by Food and Agriculture Organization (FAO) major fishing area for almost 5000 fish stocks. These data come from the CMSY algorithm for 42% of the stock (75% of the global reported fish catch) and are estimated by aggregated values for the remaining 58%.
Fault Diagnosis for Rolling Element Bearings Based on Feature Space Reconstruction and Multiscale Permutation Entropy
Authors: Zhang Weibo , Zhou Jianzhong
Published: May 2019

Aimed at distinguishing different fault categories of severity of rolling bearings, a novel method based on feature space reconstruction and multiscale permutation entropy is proposed in the study. Firstly, the ensemble empirical mode decomposition algorithm (EEMD) was employed to adaptively decompose the vibration signal into multiple intrinsic mode functions (IMFs), and the representative IMFs which contained rich fault information were selected to reconstruct a feature vector space. Secondly, the multiscale permutation entropy (MPE) was used to calculate the complexity of reconstructed feature space. Finally, the value of multiscale permutation entropy was presented to a support vector machine for fault classification. The proposed diagnostic algorithm was applied to three groups of rolling bearing experiments. The experimental results indicate that the proposed method has better classification performance and robustness than other traditional methods.
Assessment of Groundwater Vulnerability in the North Aquifer Area of Rhodes Island Using the GALDIT Method and GIS
Authors: Mavriou Zografina , Kazakis Nerantzis , Pliakas Fotios-Konstantinos
Published: May 2019

Salinization of coastal aquifer systems constitutes a major threat for groundwater. Especially areas with high population density due to increasing tourist activity may face severe problems. In this study, the GALDIT method was applied in the north side of Rhodes Island, Greece, in order to assess groundwater vulnerability to seawater intrusion. Hydrogeological data were elaborated in geographical information systems (GIS), and appropriate thematic maps were produced. The final vulnerability map was obtained from the combination of the thematic maps using overlying techniques. Based on the application of the GALDIT method, a zone up to 1000 m from the shore is characterized by medium to high vulnerability, while medium vulnerability characterizes the eastern part of the study area. Overexploitation of the aquifer, due to the intense touristic activity in Ialysos area, constitutes the main reason for groundwater salinization due to seawater intrusion in the study area. Consequently, planning of proper groundwater management and systematic monitoring of the groundwater reserves are of the utmost importance in order to solve existing problems and prevent future issues of salinization.
Tropical Dry Forest Diversity, Climatic Response, and Resilience in a Changing Climate
Authors: Stan Kayla , Sanchez-Azofeifa Arturo
Published: May 2019

Central and South America tropical dry forest (TDF) is a water-limited biome with a high number of endemic species and numerous ecosystem services which has experienced a boom in research in the last decade. Although the number of case studies across these seasonal, water-limited, tropical forests has increased, there has not been a comprehensive review to assess the physiological variability of this biome across the continent and assess how these forests respond to climatic variables. Additionally, understanding forest change and resilience under climatic variability, currently and in the future, is essential for assessing the future extent and health of forests in the future. Therefore, the objective of this paper is to provide a literature review on the variability of TDF diversity and structure across a latitudinal gradient and to assess how these components respond to differences in climatic variables across this geographic area. We first assess the current state of understanding of the structure, biomass, phenological cycles, and successional stages across the latitudinal gradient. We subsequently review the response of these five areas to differences in precipitation, temperature, and extreme weather events, such as droughts and hurricanes. We find that there is a range of adaptability to precipitation, with many areas exhibiting drought tolerance except under the most extreme circumstances, while being susceptible to damage from increased extreme precipitation events. Finally, we use this climatic response to provide a commentary on the projected resilience of TDFs under climatic changes, finding a likelihood of resilience under drying scenarios, although model projections do not agree on the magnitude or direction of precipitation change. This review of quantitative studies will provide more concrete details on the current diversity that encompasses the TDF, the natural climatic ranges under which this ecosystem can survive and thrive, and can help inform future forest management practices under climate change scenarios.
Relationships between Satellite-Based Spectral Burned Ratios and Terrestrial Laser Scanning
Authors: Kato Akira , Moskal L. Monika , Batchelor Jonathan L. , Thau David , Hudak Andrew T.
Published: May 2019

Three-dimensional point data acquired by Terrestrial Lidar Scanning (TLS) is used as ground observation in comparisons with fire severity indices computed from Landsat satellite multi-temporal images through Google Earth Engine (GEE). Forest fires are measured by the extent and severity of fire. Current methods of assessing fire severity are limited to on-site visual inspection or the use of satellite and aerial images to quantify severity over larger areas. On the ground, assessment of fire severity is influenced by the observers’ knowledge of the local ecosystem and ability to accurately assess several forest structure measurements. The objective of this study is to introduce TLS to validate spectral burned ratios obtained from Landsat images. The spectral change was obtained by an image compositing technique through GEE. The 32 plots were collected using TLS in Wood Buffalo National Park, Canada. TLS-generated 3D points were converted to voxels and the counted voxels were compared in four height strata. There was a negative linear relationship between spectral indices and counted voxels in the height strata between 1 to 5 m to produce R2 value of 0.45 and 0.47 for unburned plots and a non-linear relationship in the height strata between 0 to 0.5m for burned plots to produce R2 value of 0.56 and 0.59. Shrub or stand development was related with the spectral indices at unburned plots, and vegetation recovery in the ground surface was related at burned plots. As TLS systems become more cost efficient and portable, techniques used in this study will be useful to produce objective assessments of structure measurements for fire refugia and ecological response after a fire. TLS is especially useful for the quick ground assessments which are needed for forest fire applications.
Positive Results of an Early Intervention Strategy to Suppress a Spruce Budworm Outbreak after Five Years of Trials
Authors: MacLean David A. , Amirault Peter , Amos-Binks Luke , Carleton Drew , Hennigar Chris , Johns Rob , Régnière Jacques
Published: May 2019

Spruce budworm (Choristoneura fumiferana Clem.; SBW) outbreaks are one of the dominant natural disturbances in North America, having killed balsam fir (Abies balsamea (L.) Mill.) and spruce (Picea sp.) trees over tens of millions of hectares. Responses to past SBW outbreaks have included the aerial application of insecticides to limit defoliation and keep trees alive, salvage harvesting of dead and dying trees, or doing nothing and accepting the resulting timber losses. We tested a new ‘early intervention strategy’ (EIS) focused on suppressing rising SBW populations before major defoliation occurs, from 2014 to 2018 in New Brunswick, Canada. The EIS approach included: (1) intensive monitoring of overwintering SBW to detect ‘hot spots’ of low but rising populations; (2) targeted insecticide treatment to prevent spread; and (3) proactive public communications and engagement on project activities and results. This is the first attempt of area-wide (all areas within the jurisdiction of the province of New Brunswick) management of a native forest insect population. The project was conducted by a consortium of government, forest industry, researchers, and other partners. We developed a treatment priority and blocking model to optimize planning and efficacy of EIS SBW insecticide treatment programs. Following 5 years of over 420,000 ha of EIS treatments of low but increasing SBW populations, second instar larvae (L2) SBW levels across northern New Brunswick were found to be considerably lower than populations in adjacent Québec. Treatments increased from 4500 ha in 2014, to 56,600 ha in 2016, and to 199,000 ha in 2018. SBW populations in blocks treated with Bacillus thuringiensis or tebufenozide insecticide were consistently reduced, and generally did not require treatment in the subsequent year. Areas requiring treatment increased up to 2018, but SBW L2 populations showed over 90% reductions in that year. Although this may be a temporary annual decline in SBW population increases, it is counter to continued increases in Québec. Following 5 years of tests, the EIS appears to be effective in reducing the SBW outbreak.
Comparison of Horizontal Accuracy, Shape Similarity and Cost of Three Different Road Mapping Techniques
Authors: Kweon Hyeongkeun , Kim Myeongjun , Lee Joon-Woo , Seo Jung Il , Rhee Hakjun
Published: May 2019

Accurate spatial information on forest roads is important for forest management and harvest operations. This study evaluated the positional accuracy, shape similarity, and cost of three mapping techniques: GNSS (Global Navigation Satellite System) mapping, CAD file conversion (as-built drawing), and image warping. We chose five road routes within the national forest road system in the Republic of Korea and made digital road maps using each technique. We then compared map accuracy to reference maps made from field surveys. The mapping and field-survey results were compared using point-correspondence, buffering analysis, shape index, and turning function methods. The comparisons indicate that GNSS mapping is the best technique because it generated the highest accuracy (Root Mean Square Error: GNSS mapping 1.28, image warping 7.13, CAD file conversion 13.35), the narrowest buffering width for 95% of the routes overlapped (buffering width: GNSS mapping 1.5 m, image warping 18 m, CAD file conversion 24 m), highest shape similarity (shape index: GNSS mapping 19.6–28.9, image warping 7.2–10.8, CAD file conversion 6.5–7.4), and smallest area size difference in turning function analysis (GNSS mapping 2814–4949, image warping 7972–26,256, CAD file conversion 8661–27,845). However, GNSS requires more time (236 min/km) and costs more ($139.64/km) to produce a digital road map as compared to CAD file conversion (99 min/km and $40.90/km) and image warping (180 min/km and $81.84/km). Managers must decide on the trade-off between accuracy and cost while considering the demand and purpose of maps. GNSS mapping can be used for small-scale mapping or short-haul routes that require a small error range. Image warping was the lowest cost and produced low-accuracy maps, but may be suitable for large-scale mapping at the regional or national level. CAD file conversion was expected to be the most accurate method, because it converted as-built drawings to a map. However, we found that it was the least accurate method, indicating low accuracy of the as-built drawings. Efforts should be made to improve the accuracy of the as-built drawings in Korea.
Reaction Spinning Titanium Dioxide Particle-Coated Carbon Fiber for Photoelectric Energy Conversion
Authors: Yuan Leonardo , Wei Xupeng , Martinez Jenny P. , Yu Christina , Panahi Niousha , Gan Jeremy B. , Zhang Yongping , Gan Yong X.
Published: May 2019

In this paper, a titanium dioxide particle coated carbon fiber was prepared by reaction spinning. Polyacrylonitrile (PAN) was used as the precursor to generate a continuous carbon nanofiber. A solution containing 10% wt PAN polymer dissolved in dimethylformamide (DMF) was made as the core fluid. The sheath fluid contains 10% titanium (IV) isopropoxide, 85% ethanol, and 5% acetic acid. The two solutions were co-spun onto an aluminium plate covered with a layer of soft tissue paper. A titanium hydroxide layer formed at the surface of the PAN fiber through the hydrolysis of titanium isopropoxide due to the moisture absorption in the co-spinning process. The reaction spun fiber was converted to a partially carbonized nanofiber by the heat treatment in air at 250 °C for two hours, then in hydrogen at 500 °C for two hours. During the early stage of the heat treatment, the titanium hydroxide decomposed and produced titanium dioxide nanoparticles at the surface of the carbon fiber. The structure and composition of the carbonized fiber were studied by scanning electron microscopy (SEM). The photosensitivity of the particle-containing fiber was characterized by measuring the open circuit voltage under visible light excitation. The photoelectric energy conversion behavior of the fiber was confirmed by open circuit potential measurement. The potential applications of the composite fiber for photovoltaics and photonic sensing were discussed.
The Effect of Internal and External Heating on the Free Convective Flow of a Bingham Fluid in a Vertical Porous Channel
Authors: Rees D. Andrew S. , Bassom Andrew P.
Published: May 2019

We study the steady free convective flow of a Bingham fluid in a porous channel where heat is supplied by both differential heating of the sidewalls and by means of a uniform internal heat generation. The detailed temperature profile is governing by an external and an internal Darcy-Rayleigh number. The presence of the Bingham fluid is characterised by means of a body force threshold as given by the Rees-Bingham number. The resulting flow field may then exhibit between two and four yield surfaces depending on the balance of magnitudes of the three nondimensional parameters. Some indication is given of how the locations of the yield surfaces evolve with the relative strength of the Darcy-Rayleigh numbers and the Rees-Bingham number. Finally, parameter space is delimited into those regions within which the different types of flow and stagnation patterns arise.
Retention of Pro-Vitamin A Content in Products from New Biofortified Cassava Varieties
Authors: Eyinla Toluwalope Emmanuel , Maziya-Dixon Busie , Alamu Oladeji Emmanuel , Sanusi Rasaki Ajani
Published: May 2019

Plant breeding efforts in sub-Saharan Africa (SSA) have produced biofortified cassava with high carotenoid content to address vitamin A deficiencies (VAD). Since carotenoids in foods are easily depleted during processing, the retention of β-carotene in some newly released cassava varieties is under query. From four of these new varieties, two commonly consumed products (gari and its dough) were processed according to standard methods. Retention of β-carotene was then probed after applying fermentation periods of a day and three days. The possible contribution of the products to Vitamin A intake in children, adolescents, and women was also assessed. The concentration of β-carotene in fresh Cassava roots ranged from 5.32 to 7.81 µg/g. The percentage retention ranged from 14.4 to 29.3% and 10 to 21.7% in gari fermented for one and three days respectively. The impact of varietal difference and length of fermentation was significant on retention in the intermediate and final products (p < 0.001). When compared with dietary intake data, cooking biofortified gari into its dough reduced Vitamin A intake in most varieties. We conclude that processing Cassava into gari (especially its dough) could hinder the retention of β-carotene however some varieties have retention advantage over others irrespective of the initial concentration in their fresh roots.
Detecting Schisandrae Chinensis Fructus and Its Chinese Patent Medicines with a Nucleotide Signature
Authors: Jiang Wenjun , Ren Li , Guo Mengyue , Mantri Nitin , Zhao Sha , Pang Xiaohui
Published: May 2019

Schisandrae Chinensis Fructus (Wuweizi) is often adulterated with Schisandrae Sphenantherae Fructus (Nanwuweizi) in the herbal market. This adulteration is a threat to clinical treatment and safety. In this study, we aimed to develop a nucleotide signature for the identification of Wuweizi and its Chinese patent medicines based on the mini-DNA barcoding technique. We collected 49 samples to obtain internal transcribed spacer 2 (ITS2) sequences and developed a 26-bp nucleotide signature (5′-CGCTTTGCGACGCTCCCCTCCCTCCC-3′) on the basis of a single nucleotide polymorphism (SNP) site within the ITS2 region that is unique to Wuweizi. Then, using the nucleotide signature, we investigated 27 batches of commercial crude drug samples labeled as Wuweizi and eight batches of Chinese patent medicines containing Wuweizi. Results showed that eight commercial crude drug samples were adulterants and one of the Chinese patent medicines contained adulterants. The nucleotide signature can serve as an effective tool for identifying Wuweizi and its Chinese patent medicines and can thus be used to ensure clinical drug safety.
Insight into Heterogeneous Calcite Cementation of Turbidite Channel-Fills from UAV Photogrammetry
Authors: Marini Mattia , Della Porta Giovanna , Felletti Fabrizio , Grasso Benedetta Marcella , Franzini Marica , Casella Vittorio
Published: May 2019

Diagenesis is a key controlling factor on sandstone porosity and permeability. Understanding type, paragenetic sequence and spatial patterns of cements is thus important for assessing sandstone hydrocarbon reservoir properties. In this study Unmanned Aerial Vehicle (UAV) photogrammetry is used to evaluate the shape and spatial distribution of calcite concretions developed within the sand-prone fill of a turbidite channel. The studied channel-fill is entrenched into hemipelagic marlstones and include a lower conglomeratic sandstone loaded with marlstone rip-ups and an upper fill featuring a range of turbidite bed types, which, up-section and off the channel axis, are progressively finer grained and less amalgamated. Concretion shape analysis highlighted a continuum of equant to oblate shapes with flat-lying major axes and a cumulative volume fraction of ca. 22%. Equant to sub-equant concretions are ubiquitous and occur at different heights within beds, often developing around marlstone rip-ups. Conversely, elongated concretions are either strata-bound concretions or completely cemented beds which become volumetrically dominant up section and off the channel axis. The interparticle pore-space of concretions represents on average ca. 22% and is tightly filled by poikilotopic and blocky calcite cement precipitated near to maximum burial depth, whereas host sandstones lack calcite cements and show smectite clay cement and an average preserved porosity of ca. 15%. The oxygen and carbon isotopes of calcite cements point to the marlstone as the main source of carbonate ions, suggesting concretions developed during burial by either diffusion from rip-ups and mud caps or recrystallization of, matrix micrite. Results suggest that the process by which the carbonate-rich component was eroded from the substrate and trapped within the channel-fill is a key control on spatial distribution of calcite concretions, likely to reflect on spatial variability of reservoir properties.
Associated Factors of Drinking Prior to Recognising Pregnancy and Risky Drinking among New Zealand Women Aged 18 to 35 Years
Authors: Parackal Sherly , Parackal Mathew , Harraway John
Published: May 2019

Nearly half of all pregnant women in the Western world drink prior to recognising pregnancy. The current study aimed to investigate the factors associated with drinking prior to recognising pregnancy among pregnant women and factors associated with risky drinking among nonpregnant sexually active women. The study was a cross-sectional survey of a random sample of women aged 18 to 35 years (n = 1062) selected from the New Zealand electoral roll. Pregnant women (currently pregnant: n = 65; previously pregnant: n = 202) who were risky drinkers and who smoked in the year prior to pregnancy had five times the odds (p < 0.01) and women who planned their pregnancy (p = 0.05) and who used a community service card (p = 0.004) had less than half the odds to drink prior to recognising pregnancy than their respective counterparts. Among sexually active nonpregnant women who consumed alcohol, those who smoked in the year prior to the survey and those who drank for social reasons, for mood enhancement or coping reasons had higher odds of being risky drinkers (p < 0.05). Addressing risky drinking, especially in social settings, and smoking among women of peak childbearing age may mitigate the potential risk of drinking prior to recognising pregnancy.
Substance Use among Economically Disadvantaged African American Older Adults; Objective and Subjective Socioeconomic Status
Authors: Assari Shervin , Smith James , Mistry Ritesh , Farokhnia Mehdi , Bazargan Mohsen
Published: May 2019

Purpose. This study investigated the effects of objective and subjective socioeconomic status (SES) indicators on two health behaviors, cigarette smoking and alcohol drinking, among African American older adults. Methods. This community-based study recruited 619 economically disadvantaged African American older adults (age ≥ 65 years) residing in South Los Angeles. Structured face-to-face interviews were conducted to collect data. Data on demographic factors (age and gender), subjective SES (financial difficulties), objective SES (educational attainment), living arrangement, marital status, healthcare access (insurance), and health (number of chronic medical conditions, self-rated health, sick days, depression, and chronic pain) and health behaviors (cigarette smoking and alcohol drinking) were collected from participants. Logistic regressions were used to analyze the data. Results. High financial difficulties were associated with higher odds of smoking cigarettes and drinking alcohol, independent of covariates. Educational attainment did not correlate with our outcomes. Similar patterns emerged for cigarette smoking and alcohol drinking. Conclusion. Subjective SES indicators such as financial difficulties may be more relevant than objective SES indicators such as educational attainment to health risk behaviors such as cigarette smoking and alcohol drinking among African American older adults in economically constrain urban environments. Smoking and drinking may serve as coping mechanisms with financial difficulty, especially among African American older adults. In line with the minorities’ diminished returns (MDR) theory, and probably due to discrimination against racial minorities, educational attainment has a smaller protective effect among economically disadvantaged African American individuals against health risk behaviors.
Frailty, Quality of Life, Anxiety, and Other Factors Affecting Adherence to Physical Activity Recommendations by Hemodialysis Patients
Authors: Hornik Beata , Duława Jan
Published: May 2019

Hemodialysis patients perform little physical activity. We formulated a hypothesis that some factors, i.e., frailty, medical and functional factors, psychological factors, quality of life, awareness of recommendations, and sociodemographic factors influence the decisions of taking up physical activity. This prospective study comprised 72 dialysis patients aged 57.8 ± 16.0 ( x ¯ ± SD; in the range of 19–87 years of age). The following research tools were used: an interview about awareness of the physical activity recommendations, the Canadian Study of Health and Aging Scale (CSHA-CFS), scales for the assessment of functional status, State-Trait Anxiety Inventory (STAI), Acceptance of Illness Scale (AIS), and the questionnaire of Kidney Disease Quality of Life (KDQOL-SF 1.3). The majority of patients diagnosed with frailty did not follow the physical activity recommendations (79.3%). Quality of life was better in active patients compared to inactive patients, especially in the domains of sleep and physical performance. The severity of trait anxiety was significantly higher in patients who did not follow the recommendations compared to patients who adhered to physical activity recommendations (46.0 ± 10.5 vs. 40.0 ± 8.2; p = 0.021 ). The likelihood of adherence decreased by 1% after each subsequent month of dialysis (odds ratio = 0.99; 95% confidence interval = 0.972–0.999; p = 0.047 ). Adherence was most limited by frailty. Adherence to recommendations on physical activity was affected by: motivation, lower levels of trait anxiety, and better quality of life. Age modified the effect of awareness and acceptance of the disease on adherence to physical activity recommendations.
Overweight and Obesity among Sexual Minority Adults in the United States
Authors: Azagba Sunday , Shan Lingpeng , Latham Keely
Published: May 2019

There is evidence that sexual minority populations have a potentially heightened risk of poor health outcomes due in part to the discrimination they may face. In the present study, we examined whether overweightness and obesity vary by sexual minority subgroup using a large, nationally representative sample. Data were drawn from 2014–2017 Behavioral Risk Factor Surveillance System (BRFSS) surveys (n = 716,609). We grouped participants according to sexual identity (straight, lesbian or gay, bisexual, and other/don’t know/not sure). The propensity score matching technique was used to address covariate imbalance among sexual identity groups. In addition, subgroup analyses were performed for both males and females. Compared to straight adults, lesbian females had significantly higher odds of being overweight (OR (odds ratio) 1.33; 95% CI (confidence interval) 1.17–1.53), whereas gay males had significantly lower odds (OR 0.66; 95% CI 0.59–0.73). Similarly, lesbians were more likely to be obese (OR 1.49; 95% CI 1.31–1.70), whereas gay men had significantly lower odds of obesity (OR 0.77; 95% CI 0.69–0.86) when compared to straight adults. Bisexual females had significantly higher odds of being overweight (OR 1.21; 95% CI 1.10–1.34) and obese (OR 1.43; 95% CI 1.29–1.59), whereas bisexual males showed no significant difference. Our results strengthen previous findings and further highlight the need for research by sexual minority subgroup.
Influence of Prolonged Visual Display Terminal Use and Exercise on Physical and Mental Conditions of Internet Staff in Hangzhou, China
Authors: Cheng Xiao , Song Mengna , Kong Jingxia , Fang Xinglin , Ji Yuqing , Zhang Meibian , Wang Hongmei
Published: May 2019

To examine the effects of prolonged visual display terminal (VDT) working hours and exercise frequency on VDT-related symptoms, we recruited 944 Chinese internet staff for the study. A self-administered questionnaire survey was used to obtain the hours of daily VDT work, exercise frequency, and the physical and mental health of the participants. The daily VDT working time of participants was 8.7 hours. Musculoskeletal pain and eye complaints were prevalent, and the participants had poor mental health status. When daily VDT operation time was more than 11 hours, VDT-related symptoms, including backache (odds ratios (OR) = 3.59), wrist pain (OR = 1.88), hip pain (OR = 2.42), dry eyes (OR = 2.22), and ocular soreness (OR = 2.16) were more likely to occur, and an increased risk of serious occupational stress (OR = 6.75) and job burnout (OR = 2.66) was found in internet workers. Compared with those who never exercised, appropriate exercise frequency (three times per week) was helpful to relieve pain in the shoulders (OR = 0.28), neck (OR = 0.45), back (OR = 0.30), lower back (OR = 0.25), and wrists (OR = 0.38), as well as to prevent vision loss (OR = 0.33) and job burnout (OR = 0.42). Therefore, avoiding excessive VDT exposure and performing moderate exercise could protect the physical and mental health of internet staff from the adverse effects of VDT.