bluuebunny/crossref_metadata_2025 huggingface dataset:
Obtenção do biodiesel metílico através da transesterificação via catálise básica do óleo de coco-da-baía (Cocos nucifera L)
Authors: Ortiz Lace Valter , Matos Fraga Isabel , Castrillon Fernandez José Ricardo , Gonçalves Cláudia Roberta
Published: February 2018

O presente trabalho tevecomo objetivo principal a produção de biodiesel metílico através da reação de transesterificação via catálise básica, utilizando como matéria-prima alternativa ao óleo de soja comumente utilizado, o óleo de coco-da-baía (Cocos nuciferaL). Obiodiesel foi caracterizado quanto ao seu índice de acidez, densidade, umidade,teor de éster, ponto de fulgor, glicerol (livre, total, mono, di e triglicerol) e porcentagem máxima de metanol. Oóleo usado foi caracterizado por índice de acidez, índice de saponificação, ácidos graxos, densidade e umidade. Através destes resultados, verificou-se a qualidade do biocombustível obtido.
Uso da voltametria cíclica e da espectroscopia de impedância eletroquímica na determinação da área superficial ativa de eletrodos modificados à base de carbono
Authors: De Souza Letícia Lopes , Forbicini Christina Aparecida Leão Guedes de Oliveira
Published: February 2018

Eletrodos à base de carbono, como os eletrodos de troca iônica, entre outros, têm aplicação principalmente no tratamento de efluentes industriais e rejeitos radioativos. Carbono é também amplamente utilizado em células a combustível como substrato para os eletrocatalisadores, por possuir elevada área superficial, que supera a sua área geométrica. O conhecimento desta superfície ativa total é importante na determinação das condições de operação de uma célula eletroquímica no que diz respeito àscorrentes a serem aplicadas (densidade de corrente). No presente estudo foram utilizadas duas técnicas eletroquímicas na determinação da área superficial ativa de eletrodos de carbono vítreo e poroso e eletrodos de troca iônica: espectroscopia de impedância eletroquímica (EIE) e voltametria cíclica (VC). Os experimentos foram realizados com soluções de KNO30,1 molL-1em célula eletroquímica de três eletrodos: eletrodo de trabalho à base de carbono, eletrodo auxiliar de platina e eletrodo de referência de Ag/AgCl. Os eletrodos de carbono vítreo e de carbono poroso utilizadospossuíam uma área geométrica de 3,14 x 10-2cm2e 2,83 х 10-1cm2, respectivamente. O eletrodo de troca iônica foi preparado misturando-se grafite, carbono, resina de troca iônica e um aglutinante, sendo esta mistura aplicada emtrês camadas sobre feltro de carbono, utilizando-se nos experimentos uma área geométrica de 1,0cm2.
Determinação do número de ciclos de reuso do adsorvente cinza de casca de arroz no tratamento de um banho residual de tingimento têxtil
Authors: Barcellos Ivonete Oliveira , De Lima Thyego , Blosfeld Ana Maria
Published: February 2018

Este estudo avaliou um sistema de fluxo contínuo utilizando cinzas de casca de arroz como adsorvente para tratamentodo banhoresidualde tingimento têxtil. O sistemaconsistiu narecirculaçãodo efluentenuma buretacontendo oadsorvente.Este procedimento foi realizadoem cincociclosde reutilizaçãodo adsorvente. A Demanda Química de Oxigênioe Corforam determinadaspela estimativada eficiência doadsorventeem função do tempo, comparando os ciclosde reuso das águas residuais, antes e depois de tratadascom cinzas. A máxima eficiênciaobtidafoi de 91%no 1ºciclo. No entanto,no ciclo 5, aeficiência do adsorvente foi em torno de 46%.
Seasonality and hydrodistillation time effects on the yield and chemical composition of leaves essential oil of Piper mikanianum (Kunth) Steudel
Authors: Clemes Sabrina de Moraes , Santos Thalita Gilda , Rebelo Ricardo Andrade , Laps Rudi Ricardo , Pescador Rosete
Published: February 2018

Piper mikanianum from Santa Catarina, southern Brazil, is a well known source of safrole, an arylpropanoid precursor of several bioactive molecules. This work determined the seasonal and hydrodistillation time influence on the essential oil (EO) yield and composition. Dehydrated leaves were hydrodistilled with and without fractioning during a total period of 240 min. The EO yields varied from 0.66-0.84% with the highest values been observed during spring and summer seasons. The highest concentration of safrole was found in the winter oil (81%). In the fractioning experiments the concentration of safrole varied from 75-80% in F1 (oil distilled during 60 min) and 42-64% in F2 (oil distilled between 60-240 min).
Antibacterial potential of flavonoids with different hydroxylation patterns
Authors: Resende Flávia Aparecida , Nogueira Leonardo Gorla , Bauab Tais Maria , Vilegas Wagner , Varanda Eliana Aparecida
Published: February 2018

The antibacterial activity of ten flavonoids, with variations in the hydroxylation pattern, was assayed in this study with the aim of investigating the influence of the hydroxyl groups of flavonoids on the evaluated activity. The evaluated degree of hydroxylation of the flavonoid molecules appears to have a crucial role in antibacterial effects. Kaempferol, the most active compound against Staphylococcus aureus, has a hydroxyl group in the B ring, a double bond between carbons 2 and 3 in conjunction with a 4-carbonyl group and hydroxyl groups at positions 3, 5 and 7, showing that the hydrophilic / lipophilic balance appears to be an important variable for antibacterial activity. With respect to the strain of Escherichia coli, the compounds evaluated did not inhibit completely bacterial growth; however they reduced the percentage of Gram-negative cells, under the conditions used in this work. These studies contribute to clarify the mechanisms by which these compounds act in the evaluated activity, since flavonoids can act through different mechanisms other than conventional antibiotics and could, therefore, be of use in the treatment of resistant bacteria.
Microgravimetric method for the determination of metformin in pharmaceutical preparations and in the bulk drug
Authors: Tubino Matthieu , Bianchessi Luís Francisco , Vila Marta Maria Duarte Carvalho
Published: February 2018

This article reports a microgravimetric method for the quantitative determination of metformin in bulk and in pharmaceutical preparations. The analysis is simple and relatively rapid. A complete analysis can be performed in only an hour and thirty minutes due to the drying procedure of the precipitate. However a sample can be treated every each five minutes. The method is based on the reaction of nickel (II) with metformin that in basic medium forms an orange precipitate. The reaction is performed in a plastic syringe. The filtration was done in a glass tube containing a sintered glass disk or in Millipore® syringe filters, with posterior weighing after drying. The analytical results were statistically compared with that obtained with a HPLC and with the titrimetric method suggested by the United States and by the Japanese pharmacopoeias.
Efeito da aplicação da eletrorremediação na estrutura e nos contaminantes de catalisador desativado. Avaliação por técnicas de RMN, RPE, DRX e FRX
Authors: Leonel Raquel Folmann , Valt Renata Bachmann Guimarães , De Godoi Luciane , Ponte Maria José Jeronimo de Santana , Ponte Haroldo de Araújo
Published: February 2018

O processo de remediação eletrocinética, através da aplicação de potencial elétrico e diferentes eletrólitos, visa a mobilização e remoção de metais aderidos em catalisadores desativados de craqueamento catalítico (FCC). Neste trabalho, são estudados catalisadores desativados de FCC após o processo de remediação com soluções de citrato de sódio, ácido sulfúrico ou ácido cítrico comoeletrólitos. Foram utilizadas as técnicas de DRX, FRX, RMN e EPR de forma a avaliar as alterações resultantes. Os resultados indicaram que a remediação eletrocinética tende a reorganizar a estrutura interna do catalisador, recuperando parte da cristalinidade e removendo um percentual dos contaminantes.
Avaliação quantitativa da susceptibilidade do crescimento de Staphylococcus aureus na presença de sistemas antimicrobianos de alta complexidade
Authors: Garrido Saulo Santesso , De Oliveira Isabelle Cavalini , Zambom Carolina Reis , Vaz Aline Buda dos Santos , Marchetto Reinaldo , Barbosa Luiz Carlos Bertucci
Published: February 2018

Antimicrobial peptides (PAMs) found naturally in living organisms are a great promise for the fight against infectious diseases specially by microorganisms multiresistant to the commercial antibiotics available on the market due to intensive and inadequate applying of those substances. However, some particular characteristics that may be present in PAMs (big size, low solubility, the existence of effective load, high structural complexity, etc.) pose difficulty vis-à-vis the use of this class of substances for clinical application. As an approach to solve this technical barrier to application of PAMs, different formulations of LUV liposomes were prepared with the intent to promote the encapsulation of CcdBET2, a proven PAM, and promote its delivery in the intracellular environment. CcdBET2 was synthesized by solid-phase methodology and the 100 nm liposomes by extrusion. The peptide-liposomes systems were tested against Staphylococcus aureus by a quantitative methodology using MTT to test their ability in promote the interruption of cell growth. It is possible to suggest that the liposomal system is responsible to interact with the bacterial membrane allowing CcdBET2 to exert its antimicrobial activity.
Verificación y validación de software
Authors: Leopoldo Pauta Ayabaca Leopoldo , Moscoso Bernal Santiago
Published: February 2018

El proceso de verificación y validación (V&V) aborda todas las etapas del ciclo de vida del software de manera determinante, siendo utilizado para establecer si determinada tarea o producto, cumple con las necesidades del usuario y los requisitos establecidos para su desarrollo. V&V apoya al proceso de construcción proporcionando una valoración objetiva de los productos y los procesos que forman parte del ciclo de  vida de desarrollo del software. Estos procesos se apalancan en estándares como ISO/EEC 15288:2008 e ISO/EEC 12207:2008 que permiten aportar al software el concepto de calidad, estableciendo si los requisitos son correctos, completos, precisos, consistentes y verificables. Las pruebas son parte de un proceso más amplio de verificación y validación de software V&V, y se soporta en los estándares IEEE1008 e ISO / IEC 29119. Las pruebas de software nacen por la necesidad de garantizar un producto de calidad, descubriendo defectos que podrían contener los programas antes de la implantación, y demostrar  que un programa hace lo que se pretende que haga. El artículo busca diferenciar entre conceptos de Verificación, Validación y Pruebas, su tiempo de aplicabilidad en las diferentes fases del desarrollo de un software de calidad, y los diferentes estándares que pueden ser aplicados en función de estos conceptos.
Modification of Laplace Adomian Decomposition Method for Solving Nonlinear Volterra Integral and Integro-differential Equations based on Newton Raphson Formula
Authors: Rani Dimple , Mishra Vinod
Published: February 2018

In this paper, we establish a modified Laplace decomposition method for nonlinear volterra integral and integro-differential equations. This technique differs from the general Laplace decomposition method because of the terms involved in Adomian polynomial.We have used Newton Raphson formula in place of the $u_{i}$ in Adomian polynomial. The proposed scheme is investigated with some illustrative examples and has given reliable results.
CONCESSIONAL AGREEMENTS IN THE SPHERE OF HOUSING AND COMMUNAL SERVICES OF THE REPUBLIC OF CRIMEA
Authors: Глушко Юлия , Glushko Yuliya
Published: February 2018

The main problems in the sphere of housing and communal services of the Republic of Crimea in the article considered. Particular attention is paid to concession agreements, as an effective form of public-private partnership. The ways of development of investment activity in the form of concessions are proposed to create such legal and economic conditions under which the business will have the opportunity to cooperate with the state on mutually beneficial terms.
Infrastructural constraints of transport and logistics system of the Sverdlovsk region
Authors: Сидоренко Александр , Sidorenko Aleksandr
Published: February 2018

The article focuses on the role of transport infrastructure in the formation of transport-logistical system in the region. The analysis of the dynamics and structure of goods distribution and passenger transportation in the context presented in the Sverdlovsk region modes of transport. The infrastructural constraints typical of Sverdlovsk region in terms of modes of transport: rail, road, air. Defined strategic directions for overcoming the current situation in the medium term.
Prevalensi Kejadian Penyakit Kulit pada Anjing di My Vets Animal Clinic Bumi Serpong Damai Tahun 2016
Authors: Kristianty Tri Ayu , Efendi Zella Nofitri , Ramadhani Fathia
Published: February 2018

Pyoderma adalah dermatitis yang disebabkan oleh infeksi bakteri dan merupakan penyakit kulit yang umum terjadi pada anjing. Pyoderma pada anjing terjadi sekitar 55% dari kasus kulit yang datang ke My Vets BSD pada tahun 2016. Malassezia spp. adalah commensal yeast yang umum ditemukan pada kulit dan mukosa anjing. Infeksi Malassezia terjadi sekitar 43% dari kasus kulit yang datang ke My Vets BSD pada tahun 2016. Infestasi parasit pada kulit anjing yang umum terjadi disebabkan oleh mites dan serangga. Infestasi parasit pada anjing terjadi sekitar 9% dari kasus kulit yang datang ke My Vets BSD dengan parasit yang paling umum adalah Demodex spp. Ras anjing yang paling sering terkena penyakit kulit dari keseluruhan anjing yang datang ke My Vets BSD di antaranya adalah Beagle dengan jumlah sekitar 11%, Shih Tzu dengan jumlah sekitar 11%, dan Mongrel dengan jumlah sekitar 16%. Berdasarkan data tersebut, kasus kulit yang paling banyak terjadi dibandingkan dengan kasus kulit lain di My Vets BSD pada periode tahun 2016 adalah pyoderma dan anjing yang paling sering terkena penyakit kulit adalah Mongrel.
Fistula tembolok pada kakatua putih (Cacatua alba)
Authors: Paramita Intan Maria , Fajrin Leoisna Nirbhita , Oktrianinta Ranin , Darmawan Haris
Published: February 2018

Pemeliharaan burung kakatua di Indonesia secara individual menyebabkan burung mudah mengalami stress dan menimbulkan perilaku feather pecking atau mencabuti bulunya sendiri. Perilaku ini dapat menyebabkan luka pada area yang bulunya dicabuti dan jika hal tersebut terjadi di area tembolok akan menyebabkan fistula tembolok. Fistula juga dapat disebabkan oleh kesalahan manajemen pakan dengan memberikan pakan terlalu banyak atau terlalu panas. Tembolok yang sudah berlubang dapat diperbaiki dengan melakukan penjahitan dan pemberian enrofloxacin secara oral. Pencegahan yang dapat dilakukan adalah dengan memperbaiki edukasi klien terkait manajemen pemberian pakan agar tidak terlalu banyak atau terlalu panas, dan juga terkait enrichment pada kakatua yang dipelihara secara individual.
Diagnosa Radiografi dan Penanganan Penyakit Periodontal pada Anjing Yorkshire Terrier
Authors: Hafizhuddin Muhammad Faiz , Zaenab Siti , Noviana Deni
Published: February 2018

Tujuan studi kasus ini adalah mengetahui gambaran radiografi serta penanganan kasus penyakit periodontal pada anjing Yorkshire Terrier. Radiografi dilakukan dengan menggunakan teknik paralel pada gigi premolar dan molar mandibula anjing. Studi kasus ini menggunakan anjing jantan jenis Yorkshire Terrier. Hasil pengambilan gambar radiografi menunjukan adanya penurunan densitas pada sekitar gigi molar 308 yang memiliki nilai indeks plak, gingivitis, dan furcation yang tinggi dibandingkan dengan gigi yang memiliki nilai indeks yang kecil yaitu gigi 306. Selain itu, pada gigi 308 didapatkan sulkus gingiva sedalam 0.3 mm. Pencabutan gigi anjing dilakukan pada seluruh gigi incisor mandibula.  Berdasarkan studi kasus yang dilakukan, diagnosa untuk melakukan penanganan penyakit periodontal dapat dilakukan dengan radiografi.
Profil Hematologi Sederhana pada Trenggiling Jawa (Manis Javanica) yang Mengalami Diare Kronis
Authors: Rifai Muhammad Sulthan Rasyid , Choliq Chusnul , Nisa Chairun , Hambandima Danny Umbu Tay
Published: February 2018

Seekor trenggiling jawa (Manis javanica) jantan berusia lima tahun menderita diare kronis selama dua bulan. Pemeriksaan hematologi dilakukan secara manual untuk mengetahui kondisi fisiologis trenggiling dengan parameter Red Blood Cell (RBC), White Blood Cell (WBC), Packed Cell Volume (PCV), hemoglobin (Hb), indeks RBC, dan diferensial WBC. Trenggiling diidentifikasi mengalami polisitemia relatif, dehidrasi, anemia mikrositik-normokromik, indikasi hipoksia, dan neutrofilia. Kondisi ini disebabkan oleh diare kronis akibat infeksi multi kausa dengan didominasi oleh infeksi bakteri yang menyebabkan trenggiling mengalami malnutrisi dan stres secara fisik dan fisiologis.
Pencitraan Ultrasonografi Organ Hepatobiliari pada Ular Sanca
Authors: Lestari Nurul Aeni Ayu , Pertiwi Amira Putri , Kombo Muhammad Piter , Tumbelaka Ligaya ITA , Ulum Mokhamad Fakhrul
Published: February 2018

Teknologi pencitraan ultrasonografi memiliki peranan penting dalam manajemen kesehatan pada ular sanca. Struktur sistem organ di dalam tubuh seperti hepatobiliari dapat dipantau secara non-invasif menggunakan teknologi ultrasonografi. Citra ultrasonografi organ hepatobiliari pada tiga spesies ular sanca, yang terdiri atas sanca batik, sanca bodo, dan sanca bola dilaporkan dalam tulisan ini. Pencitraan organ hepatobiliari dilakukan menggunakan trasnduser linear dengan frekuensi 10 MHz. Ukuran organ hepatobiliari diukur berdasarkan nomor dan jumlah sisik ventral tubuh. Hasil pengukuran menunjukkan bahwa organ hati pada ketiga sanca memiliki ukuran yang bervariasi dan berada di antara persinggungan nomor sisik ventral 72-102. Organ kelenjar empedu berukuran 7-9 sisik dan berada di antara nomor sisik ventral yang bervariasi. Derajat ekogenitas organ hepatobiliari di antara ketiga sanca tidak menunjukkan adanya perbedaan. Ekogenisitas organ hati pada ketiga sanca tampak hipoekoik dengan dinding hiperekoik di antara bayangan organ paru-paru yang tampak hiperekoik. Kelenjar empedu tampak anekoik dengan dinding hiperekoik berada diantara organ limpa yang tampak hiperekoik dan organ pankreas yang tampak hipoekoik.
Efektifitas Penggunaan Antibiotik Beta Laktam dan Amitraz Topikal untuk Demodikosis Lokal pada Anjing Golden Retriever
Authors: Kristianty Tri Ayu , Ichsanniyati Zulfa , Setiawati Anjani Retno , Efendi Zella Nofitri , Budiharjo Bagus Satrio , Ramadhani Fathia
Published: February 2018

Demodex canis adalah mikroflora normal komensal pada kulit anjing. Demodex spp. berhabitat di bawah folikel rambut atau kelenjar sebum. Bakteri kokus juga merupakan mikroflora normal pada kulit dan umum ditemukan pada kondisi infeksi kulit. Infeksi bakteri pada kasus demodikosis terjadi sebagai kejadian sekunder. Antibiotik beta laktam merupakan golongan antibiotik pilihan yang digunakan terhadap kasus infeksi bakteri kokus. Amitraz adalah akarisida topikal dan digunakan pada kasus demodikosis. Anjing Golden Retriever berusia 7 tahun datang ke My Vets Animal Clinic Bumi Serpong Damai (BSD) dengan kondisi kedua pipi erythema, pustul, erosi, dan pruritic akibat demodikosis dan infeksi sekunder bakterial. Anjing tersebut diberikan terapi fluralaner oral satu kali untuk satu bulan dan amitraz topikal setiap minggu untuk mengatasi demodikosis. Lesi pada anjing tersebut tidak terlihat berkurang nyata. Terapi antibiotik beta laktam oral kemudian diberikan untuk membantu mengatasi infeksi bakteri yang diduga terjadi sekunder dari demodikosis tersebut dan amitraz topikal diberikan setiap hari pada lesi di kedua pipi tersebut. Terapi ini menunjukkan perbaikan yang nyata dalam 8 hari. Lesi erythema, pustul, dan erosi semakin berkurang nyata dan lesi pustule sudah menghilang pada pemberian antibiotik hari keempat. Berdasarkan pengamatan, penggunaan antibiotik beta laktam dan amitraz topikal cukup efektif pada kasus demodikosis lokal.
Diagnosa Radiografi Kasus Hernia pada Kucing
Authors: Vidiastuti Dian
Published: February 2018

Hernia terjadi akibat kelemahan dinding abdomen sehingga memungkinkan bagian usus atau organ lain melewati celah abdomen mengakibatkan penonjolan. Dua ekor kucing jantan, berumur sekitar 3-4 bulan, menjalani pemeriksaan radiologi di Rumah Sakit Hewan Pendidikan Universitas Brawijaya. Gambaran radiografi kasus 1 gejala dyspnea dengan standar pandang left lateral menunjukkan usus terjepit masuk di dalam rongga thorax dengan diagnosa peritoneo-pericardial diaphragmatic hernia (PPDH). Pada kasus 2 dengan gejala perut kanan membesar, tampilan radiografi standar pandang dorso ventral menunjukkan hernia inguinalis akibat trauma.
Sonometri fetus kambing kacang usia 7 minggu hasil superovulasi menggunakan hormon PMSG
Authors: Arif Ridi , Andriyanto . , Boediono Arief , Winarto Adi , Satrija Fadjar , Manalu Wasmen
Published: February 2018

Teknologi superovulasi dapat dimanfaatkan untuk meningkatkan sekresi endogen hormon kebuntingan. Salah satu manfaat dari peningkatan sekresi endogen hormon kebuntingan adalah perbaikan perkembangan lingkungan uterus selama kebuntingan. Kambing Kacang betina sebanyak 8 ekor dan telah dewasa kelamin dengan bobot rataan 22 kg dibagi ke dalam dua kelompok yaitu kelompok kontrol (tidak disuperovulasi) dan kelompok superovulasi menggunakan hormon Pregnant Mare Serum Gonadotropin (PMSG) dengan dosis 15 IU/kgBB. Kambing Kacang percobaan diserentakkan berahinya menggunakan PGF2α sebanyak 2 kali dengan selang 11 hari. Penyuntikan PMSG dilakukan bersamaan dengan penyuntikan PGF2α kedua pada kelompok superovulasi. Setelah berahi, semua kambing dikawinkan secara alami dengan pejantan pilihan. Fetus kemudian diukur secara ultrasonografi (USG) pada usia kebuntingan 7 minggu. Hasil pengukuran menunjukkan kelompok Kambing Kacang hasil superovulasi memiliki ukuran fetus yang lebih panjang daripada kelompok kontrol (P<0.05). Ukuran diameter amnion terpanjang dan terpendek serta tebal dinding uterus terlihat cenderung meningkat pada kelompok superovulasi dibandingkan dengan kelompok kontrol (P>0.05). Kesimpulan penelitian ini adalah superovulasi pada induk Kambing Kacang mampu meningkatkan pertumbuhan fetus sampai dengan usia kebuntingan 7 minggu.
Analisis kadar fibrinogen sebagai biomarker diabetik pada tikus wistar yang diinduksi streptozotocin
Authors: Rosyadi Imron , Romadhona Ella , Utami Ajeng Tyas , Hijrati Yayik Nur , Santosa Christin Marganingsih
Published: February 2018

Penyakit diabetes mellitus adalah serangkaian proses penyakit yang bermula dari kerusakan jaringan terutama di pankreas dimana awalnya ditandai dengan munculnya protein fase akut. Pada mamalia, konsentrasi protein fase akut yang dominan adalah serum amyloid A protein, C-reaktive protein dan fibrinogen. Penelitian ini bertujuan untuk mencari korelasi protein fase akut fibrinogen untuk digunakan sebagai biomarker pada tikus diabetes yang diinduksi streptozotocin. Tikus yang digunakan adalah tikus Wistar jantan sebanyak 20 ekor, umur sekitar 2 bulan dengan berat badan 180-250 gram. Tikus dibagi menjadi dua kelompok, masing-masing kelompok 10 ekor tikus sebagai kelompok perlakuan (I) dan kelompok kontrol (II). Kelompok I dipuasakan selama 24 jam kemudian diinjeksi streptozotocin 1 kali dengan dosis 40 mg/kg bb yang dilarutkan dalam bufer sodium sitrat 0,1 M pH 4,0. Tikus diambil darahnya pada jam ke-0, 6, 12, 24, 48, 60, 72, 84 dan 96  post induksi diabetes untuk diperiksa kadar konsentrasi protein fase akut fibrinogen Hasil penelitian rata-rata kadar fibrinogen pada jam ke-0 dan ke-6 yaitu sebesar 0,57±0,06 mg/mL dan 0,60±0,35 mg/mL masih dalam range normal, kemudian mulai meningkat terus berturut-turut di jam ke-12 sebesar 0,6±0,4 mg/mL, jam ke-24 0.93±0,46 mg/mL, jam ke-36 1,1±0,1 mg/mL, jam ke-48 1,13±0,81 mg/mL, jam ke-60 1,17±0.40 mg/mL, jam ke-72 1,47±0,06 mg/mL, jam ke-84 1,6±0,1 mg/mL dan jam ke-96 1,8±0,1 mg/mL. Hasil dari penelitian ini menunjukkan protein fase akut fibrinogen dapat dijadikan sebagai salah satu marker pada tikus yang diinduksi diabetes mellitus.
Pengaruh Investasi, Kapasitas Produksi, Nilai Produksi dan Jumlah Unit Usaha pada Sektor Industri Terhadap Penyerapan Tenaga Kerja di Kabupaten Bulungan
Authors: Aslan Aslan
Published: February 2018

The purpose of this study was to determine How much influence the investment to the production capacity in the district of Bulungan, To know How much influence the production capacity of the production value in the district of Bulungan, To know How much influence the production value of the number of business units in the district of Bulungan, To know How large indirect effect of investment on employment in the industrial sector through the production capacity in the district of Bulungan, To know How big is the indirect effect of production capacity in the labor market in the industrial sector through the production value in the district of Bulungan, To know How much influence the indirect value production on employment in the industrial sector through a number of business units in the district of Bulungan. The results of the research are investments (X1) direct effect on employment (Y) of 0.667. Production Capacity (X2) direct effect on employment (Y) of -0.040. Value of Production (X3) direct effect on employment (Y) of -0.282. Total Business Unit (Y1) direct effect on employment (Y) of 0.957. Investments (X1) direct effect on employment in the industrial sector through the production capacity (X2) is 0,053. Production capacity (X2) direct effect on employment in the industrial sector through the production value (X3) of 0.395. The production value (X3) direct effect on employment in the industrial sector through a number of business units (X4) of 0.886.Keywords:  Investation, Product Capacity, Product Value, Number of Business Units, Employment Absorpt
Akuntabilitas pada Organisasi Religi; Studi Kasus Masjid-Masjid di Balikpapan, Kalimantan Timur
Authors: Fitria Yunita
Published: February 2018

The study aims to test the accountability of the organization in the mosques located in Balikpapan, Kalimantan Timur. This study uses the concept of accountability mechanisms presented by Ebrahim (2003). Data is collected by interview, observation, field notes and document analysis. The study uses semi-structures interview used to explore the perception of mosque board. This study examines 3 mosque organizations and 15 people became interviewees. An interesting result in the study was informal accountability form in Balikpapan mosque. The study consisted of only a few people interviewed, so the results should be interpreted in context and not generalizable. The limitations of this study were that most mosques coud not show the full financial report due to the confidentiality of their financial statements. These findings illustrated to the government about informal accountability in mosques. Thus, this study provides an overview of other studies to see more about accountability in non-profit organizations.Keywords: Accountability, non profit organization, Balikpapan, mosque
Pengaruh Struktur Corporate Governance terhadap Integritas Laporan Keuangan Perusahaan pada Perusahaan LQ45 yang Terdaftar di BEI
Authors: Istiantoro Inosensius , Paminto Ardi , Ramadhani Herry
Published: February 2018

The influence of Corporate Governance Structure  on Integrity Corporate Financial Statements of the LQ45 companies listed on the Indonesia Stock Exchange 2009-2014. (Under the guidance of Dr. H. Ardi Paminto, MS and Herry Ramadhani, SE., MM). The purpose of research is to analyze the influence of Corporate Governance Structure on Integrity Corporate Financial Statements of the LQ45 companies listed on the Indonesia Stock Exchange 2009-2014. The data used in this study is 18 companies using criteria through purposive sampling method. Analysis of the data used in this study is the classical assumption test and multiple linear regression SPSS 19.0. The results of this study indicate that the institutional ownership has a negative and significant influence on integrity corporate financial statements, Managerial Ownership is positive but no significant effect on integrity corporate financial statements, Audit Committee is positive and has a significane effect on integrity corporate financial statements, Independent Commissioner is negative and no significant effect on integrity corporate financial statements.Keywords:  Institutional Ownership, Managerial Ownership, Audit Committee and Independent Commissioner.
Dampak Makro Ekonomi terhadap Profitabilitas Bank BPD di Indonesia
Authors: Fathunnida Fathunnida , Defung F. , Yudaruddin Rizky
Published: February 2018

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana Pengaruh Inflasi, Tingkat Suku Bunga dan GDRP Terhadap Profitabilitas pada Bank BPD di Indonesia selama periode tahun 2010-2013. Data diperoleh dari Laporan Keuangan publikasi yang diterbitkan oleh Bank Indonesia dengan periode waktu tahun 2010-2013. Jumlah populasi penelitian ini adalah 26. Penelitian ini menggunakan Regresi Data Panel dengan metode Random Effect Method (REM) melalui program Eviews 8. Hasil dari penelitian ini menunjukan bahwa Inflasi berpengaruh positif tidak signifikan terhadap Profitabilitas, Tingkat Suku Bunga berpengaruh positif signifikan terhadap Profitabilitas dan GDRP berpengaruh negatif signifikan  terhadap Profitabilitas pada Bank BPD di Indonesia selama periode tahun 2010 hingga 2013.
Analisis Assigment Problem Berdasarkan Penilaian Kinerja Karyawan Menggunakan Metode Hungarian (HUNGARIAN METHOD) dan Pohon Keputusan (DECISION TREE)
Authors: Husniati Nur , Judiarni Justina Ade , Adhimursandi Doddy
Published: February 2018

Analisis Penugasan Soal Berdasarkan Penilaian Kinerja Dengan Menggunakan Metode Hungaria (Metode Hungaria) dan Pohon Keputusan (Decision Tree) pada PT Suryabumi Tunggal Perkasa di Kutai Kartanegara. Dipandu oleh Ibu Justina Ade Judiarni dan Pak Doddy Adhimursandi. Tujuan dari penelitian ini adalah untuk mendapatkan penugasan hak kepada karyawan, dengan menggunakan data dari penilaian produksi dan kinerja yang diperoleh dari PT Surya Bumi Tunggal Perkasa. Alat analisis yang digunakan dalam penelitian ini adalah metode Metode Hungarian atau Assignment yang merupakan teknik pemecahan masalah penugasan kepegawaian. Untuk dapat menerapkan metode ini, jumlah sumber daya dan jumlah tugas harus sama banyaknya di mana masing-masing sumber daya ditugaskan untuk satu tugas. Selain metode Hungaria yang digunakan juga merupakan alat analisis Decision Tree adalah alat manajemen dalam membuat keputusan tentang isu-isu kompleks, sekuensial dan membutuhkan serangkaian rincian sekuensial dalam kerja tim yang baik. Penelitian dilakukan dengan wawancara, observasi dan studi pustaka. Dari hasil penelitian ini disimpulkan bahwa penugasan yang dilakukan oleh perusahaan saat ini sudah optimal, berdasarkan hasil produksi sebesar 378 (ratusan ton) dan penilaian kinerja dengan total skor 356. Berdasarkan analisis tugas pegawai Daud Sianipar harus ditugaskan ke Divisi II, Andi Pratama ditugaskan ke Divisi III, Willy Tuba ditugaskan ke Divisi IV dan Tiki Fajar ditugaskan ke Divisi I.
Con esta Edición Especial
Authors: Martínez Molina Oscar Antonio
Published: February 2018

Con esta Edición Especial, la Revista arbitrada Scientific, editada en el mes de Febrero del 2017, se presenta una temática nutrida y multidisciplinaria, desde la relación de la Educación Ambiental, en ese compartir ecológico hombre-ambiente; la responsabilidad social desde el entorno de la Gerencia y los valores motivacionales conducentes al desempeño docente en los diversos niveles educativos.

Veinticinco (25) artículos, generados de la producción investigativa en los ambientes universitarios a nivel Internacional, son firma de la calidad de artículos/ensayos que presentamos en esta Edición Especial. Son varios los motivos que impulsan la pluma literaria de nuestros autores, ajustándose al ritmo de los tiempos y al uso de las nuevas tecnologías; y en correspondencia con el cuidado del ambiente, esta forma de divulgar y visibilizar los contenidos científicos de corte humanístico y social, apoyan el cuidado y protección de los bosques, al ser una producción en línea, en el Cloud.

Gracias al soporte del Instituto Internacional de Investigación y Desarrollo Tecnológico Educativo INDTEC, C.A., la Revista Scientific, ha podido desarrollarse a partir del trabajo cooperativo de las personas que componentes sus diferentes comités: Comité Académico Editorial, Comité Científico Académico y los Árbitros en la revisión y valoración de la calidad de los artículos.

Con estos activos, la Revista Scientific, apertura al público en general y en especial, al académico nuevos horizontes intelectuales.
Hubungan Penguasaan Perkalian dan Pembagian Dasar terhadap Prestasi Belajar Matematika Siswa Kelas VIII SMP PMDS Putra Palopo
Authors: Rahmah Nur , Asnidar Asnidar
Published: February 2018

Permasalahan pokok penelitian ini adalah (1) bagaimana penguasaan perkalian dan pembagian dasar peserta didik kelas VIII SMP PMDS Putra Palopo?; (2) bagaimana prestasi belajar matematika peserta didik kelas VIII SMP PMDS Putra Palopo?; (3) apakah penguasaan perkalian dan pembagian dasar mempunyai hubungan yang signifikan terhadap prestasi belajar matematika peserta didik kelas VIII SMP PMDS Putra Palopo?. Penelitian ini merupakan penelitian ex-post facto. Populasi dalam penelitian ini adalah kelas VIII PMDS Putra Palopo tahun pelajaran 2013/2014 sebanyak 32 orang. Sampel yang digunakan adalah sampel jenuh. Instrumen yang digunakan berupa tes uraian dan nilai rapor kelas VII semester II. Teknik analisis data yang dilakukan yaitu analisis statistik deskriptif dan inferensial. Hasil analisis statistik deskriptif menunjukkan bahwa penguasaan perkalian dan pembagian dasar peserta didik berada pada kategori baik dengan nilai rata-rata 70,56 dengan varians 104,835 serta standar deviasi 10,239 dan rentang skor 45. Sedangkan prestasi peserta didik berada dalam kategori baik dengan nilai rata-rata 74,06 dengan varians 81,351 dan rentang skor 45. Hasil statistik inferensial menunjukkan bahwa thitung > ttabel  sehingga dapat disimpulkan bahwa terdapat hubungan yang signifikan antara penguasaan perkalian dan pembagian dasar peserta didik dengan prestasi belajar matematika siswa.
BAĞIMSIZLIKLARINI KAZANDIKTAN SONRA TÜRK CUMHURİYETLERİNİN DİL POLİTİKALARI VE TÜRKİYE İLE ORTAK DİL VE ORTAK ALFABE ÇALIŞMALARI
Authors: Abdıeva Rakhat
Published: February 2018

Sovyetler Birliğinin dağılmasından sonra Türk
Cumhuriyetlerinde bağımsızlığın ilk yıllarında Sovyetler Birliği, özellikle de
Rusya’nın izlerini taşıyan birçok alanda değişiklik yapılmıştır. Bu
değişikliklerin başında cumhuriyetlerin kendi anayasalarının kabul edilmesi,
bayrak ve armalarının tespit edilmesi, kendi para birimlerinin belirlenmesi
gibi değişiklikler gelmektedir. Ayrıca bu dönemde devlet dili, dil politikası,
diğer Türk Cumhuriyetleri ile ortak bir yazı dili ve ortak alfabe konuları
gündeme gelmiştir. Çalışmada Türk Cumhuriyetleri arasında oluşturulması
planlanan ortak dil ve ortak alfabe çalışmaları, cumhuriyetlerin uyguladığı dil
politikaları ve bu çalışmalarda günümüzde gelinen nokta değerlendirilmeye
çalışılmıştır.
Promoting Collaboration in Jabodetabekjur: A Learning Regions Perspective on Knowledge-Based Economy
Authors: Yananda Muhammad Rahmat , Maksum Irfan Ridwan , Fathurahman Heri
Published: February 2018

This research raised issues on knowledge – based economy (KBE) in Jabodetabekjur, especially Bogor, Depok and South Tangerang. Using qualitative approach, this research examines collaboration involving city governments, college/research institutions, businesses/industries,communities and found the reasons why collaborations for the beneft of KBE in Jabodetabekjur as a learning region has not established yet. The causes are: (1) lack of cohesion in terms of policy/administration, ecology, economics and social system; (2) institutional failure; (3) non optimalregional cooperation; (4) unalignment with the national urban development strategies; and (5) loss of momentum in KBE development. Learning regions can be constructed by analyzing a path or trajectories combined with the potentials of the urban region elements (Academicians, Businesses, Communities and Governments). They can also be constructed via governance approach and development of appropriate organizational models. City’s administrations should take active roles as the initiator of the collaboration process opted by certain types and activities. Strategy and policy – making related to collaboration gave rise to: (1) KBE development themes; (2) vision/ mission statements; and (3) principles of engagement and capacities. Resources gaps were found and can be applied as inputs to build joint projects, namely: (1) incubation and innovation centers; and (2) product innovation promotion center.
Relation among Stakeholders in HIV/AIDS Response Case Study: Palu Municipality
Authors: Sari Mustika , Lele Gabriel
Published: February 2018

This study aims at acquiring data and information regarding why there is an increasing annual trend of HIV/AIDS in the city of Palu. In order to answer the aforementioned question, this research focused on the relation established among stakeholders involved in HIV/AIDS response.The ongoing trend of HIV/AIDS in the city of Palu has always been confronted with HIV/AIDS response policies in the form of: (1) fnding as much cases as possible; (2) preventive measures; (3) policies on medication, support and treatment/care; and (4) empowerment policy. However,research results show that the increasing trend of HIV/AIDS found in the Palu Municipality is due to the poorly established relation among stakeholders, be it key stakeholders, primary stakeholders, or secondary stakeholders. In addition to the poor relationship established among stakeholders being observable through a number of negative characteristics seen in their interactional and relational paterns, it was also found that the said relation was inﬂuenced by each of the stakeholders’ power and interests.
The Inﬂuence of Spiritual Leadership on Organizational Culture at Bank Syariah Mandiri Branch Office and Sub Branch Office Depok
Authors: Jabbar Abdul , Kusumastuti Retno
Published: February 2018

This research aims to examine and analyze the inﬂuence of spiritual leadership on organizational culture implemented by Bank Syariah Mandiri (hereinafter will be referred as “BSM”) Branch Ofce and Sub Branch Ofce Depok. Spiritual leadership can be measured by using the concept of spiritual leadership developed by Fry (2003) with fve dimensions, namely: vision, altruistic love, hope/faith, meaning/calling, membership, and organizational culture as measured by the ETHIC (Excellence, Teamwork, Humanity, Integrity, and Customer Focus) dimensions in Bank Syariah Mandiri’s organizational culture. This research utilized a quantitative approach wherein research data were collected through survey conducted to all employees in the BSM Branch Ofce and Sub Branch Ofce Depok, with 55 respondents being involved in this research. The research data were subsequently analyzed by using descriptive statistics analysis and simple linier regression analysis. The results of this research show that spiritual leadership of the Head of BSM Branch Ofce Depok has a 56 percent positive eﬀect on the implementation of ETHIC organizational culture in BSM.
The Adaptability of The Society in Dealing with The Vulnerability of Earthquake Threats in Bantul
Authors: Delfi Delfi
Published: February 2018

Earthquake in Bantul on May 27, 2006 brought catastrophic impacts for society as the victims. There were the most serious damages and highest number of victims in Bawuran Village. On the other hand, Srigading Village had the lowest damages and there was no victim. Bawuran Village is located on graben which causes its vulnerability towards earthquake threat. Meanwhile, Srigading Village is situated on 3-10 meters above the sea level, which makes it vulnerable to tsunami. The adaptation capacity is very important to minimize the costs of natural disasters. Based on the reviews of those backgrounds, the researcher will examine the societal adaptation capacity in Bawuran and Srigading Village regarding to its vulnerability towards tsunami and earthquake. Societal adaptation capacity can be seen as society’s readiness in facing natural disasters. This research uses qualitative-descriptive method. Data collecting techniques are done by using literature study, field observation through interview and documentation. The researcher also has conducted an in-depth interview with the local government i.e. the oﬃcers of Regional Disaster Management Agency (BPBD) in Bantul Regency. The result of this research is to find out the society’s adaptation capacity towards earthquake, drought, landslide, flood, fallen tree, tornado and river flow closing in Bawuran Village. Meanwhile in Srigading Village, the risk of tsunami, flood and puddle have been found. The society’s adaptation capacity in Bawuran and Srigading Village can be assessed by using economic growth, social capital, information and communication, and social competence. Based on those assessments, societies do not have readiness in facing disasters yet. It is caused by poor economic condition, inadequate economic resources with low incomes in Bawuran Village, and the uneven population of Srigading Village. The networks within the community have not been fully developed. The community also cannot access information through the internet network. This is due to the unavailability of internet facilities in the two villages. It also lacks of disaster management competency. This condition is indicated by the absence of disaster programs in the two villages. Awareness from the society, especially the victims in responding disasters is also needed. The result of research shows that societies do not have readiness in facing any upcoming disasters yet.
Revisiting Understanding of The Whistleblowing Concept In The Context of Indonesia
Authors: Nurhidayat Ilham , Kusumasari Bevaola
Published: February 2018

The conduct of this study came in the backdrop of thinking of the need for opening a discussion for a more comprehensive and contextual concept of whistleblowing  for Indonesia from the vantage point of existing theoretical perspectives, regulations and practices. There is a lot of misunderstanding and bias about the concept of whistleblowing in public and private organizations in Indonesia. This study is largely based on previous literature and observation of the implementation of whistleblowing system (WBS) in several institutions that the author considered credible enough to be best practices. The study used descriptive qualitative approach and used various reference sources that were drawn from library research. This research has produced several formulations. First, the synonym or equivalent phrase in the Indonesian language for the term whistleblower is Pengungkap dugaan kecurangan, (revealer of alleged fraud) and Pengungkap dugaan pelanggaraan (revealer of alleged violation) or Pengungkap dugaan perbuatan tidak benar (wrongdoing) (revealer of alleged wrongdoing). Secondly, the most appropriate equivalence to the phrase whistleblowing system (WBS) in the context of Indonesia is “Sistem Pengungkapan Dugaan Pelanggaran” (alleged violation disclosure system). Third, the object of the report or complaints of whistleblowing (wrongdoing) is classifying into seventeen types of behavior that are in turn categorized into seven groups. WBS development and implementation in a number of government and private sector institutions emphasize seven key points. Research findings fill a mainstream research gap on whistleblowing in  Indonesia, which has for long been plagued by misunderstanding  between  WBS and  complaints handling system that is evident in several institutions and  government agencies in Indonesia. The expectation is that research results will make some contribution to government policy making in the realm of whistleblowing system by providing a definition that is in line with the initial conception of the concept of whistleblowing. That way, this research is expected to contribute to the development of a more effective policy and WBS that not only protects the whistleblower but also pays attention ethics, culture, and local context in Indonesia which are different from the countries where the concept of whistleblowing had its origins.
Multi-fractal characteristics of particle size distribution of granular backfilling materials under different loads
Authors: Yan Hao , Zhang Jixiong , Wang Jiaqi , Zhou Nan , Zhang Sheng
Published: February 2018

This study is focused on the inhomogeneity and local heterogeneity of the particle size distributions (PSD) of granular backfilling materials (eolian sands and loess) from western mines of China under overburden strata loads. The multi-fractal spectrum and variations in corresponding parameters of PSD of granular backfilling materials were obtained under different loads using a laser particle size analyzer and an environmental scanning electron microscope (ESEM). The results indicated that the load had negligible effects on the multi-fractal characteristics of PSD of eolian sand. There were no significant variations in the capacity dimension D(0), the information entropy dimension D(1) and the bandwidth of the multi-fractal spectra (Δα) as a function of the load. In contrast, the load significantly affected the multi-fractal characteristics of the PSD of loess, and D(0), D(1) and Δα increased and then decreased (maximized at 2 MPa) as the load increased. Furthermore, there was a correlation between structural morphology parameters and multi-fractal parameters in the particle breakage process, which demonstrated that D(0), D(1) and Δα of PSD of granular backfilling materials could effectively reflect the particle breakage and the change of structural morphology parameters of backfilling materials under different loads.
Treatment of medically refractory seizures with responsive neurostimulation: 2 pediatric cases
Authors: Kokoszka Malgosia A. , Panov Fedor , La Vega-Talbott Maite , McGoldrick Patricia E. , Wolf Steven M. , Ghatan Saadi
Published: February 2018

The responsive neurostimulation (RNS) system, an adjunctive treatment for pharmacoresistant partial-onset seizures with 1 or 2 foci, has been available to patients aged 18 years or older since the device’s FDA approval in 2013. Herein, the authors describe their off-label application of this technology in 2 pediatric patients and the consequent therapeutic benefit without surgical complications or treatment side effects. A 14-year-old nonambulatory, nonverbal male with severe developmental delay was considered for RNS therapy for medically and surgically refractory epilepsy with bilateral seizure onsets in the setting of a normal radiological examination and a known neuropathological diagnosis of type I cortical dysplasia. The RNS system was implanted with strip electrodes placed on the left lateral frontal and right lateral temporal neocortex. At 19 months’ follow-up, cortical stimulation resulted in sustained reduction in both seizure frequency—3 seizures per day down from 15 to 30 per day—and seizure severity. The patient subsequently underwent a trial of corticothalamic stimulation with a right temporal cortical strip and a left thalamic depth electrode, which resulted in a further 50% reduction in seizure frequency. In a second case, a 9-year-old right-handed female with radiological evidence of a small watershed infarct on the left and medically refractory seizures was referred for presurgical evaluation. Invasive monitoring revealed an unresectable seizure focus in the eloquent cortex of the left posterior frontal and parietal lobes. The RNS device was implanted with cortical leads placed at the putative seizure focus. At 21 months after surgery, the patient had been seizure free for 4 months, following a 17-month period in which the seizure frequency had decreased from 12 per month to 2 per month, with associated functional and behavioral improvement. The authors’ results suggest that RNS may be a palliative option for children with intractable seizures whose condition warrants off-label use of the surgical device. The improved therapeutic effect noted with time and sustained RNS treatment points to a possible neuromodulatory effect.