bluuebunny/crossref_metadata_2025 huggingface dataset:
COMBINED THERAPY WITH MEDICAL GASES AND RESPIRATORY SUPPORT IN PATIENTS WITH HYPERCAPNIC RESPIRATORY FAILURE WITH EXACERBATION OF COPD
Authors: Truong T.T. , Selimir D.S. , Panin A.A. , Chuchalin A.G.
Published: November 2021

COPD is one of the leading causes of morbidity and mortality in the Russian Federation. The prevalence reaches 6-10% of the general population. Severe and frequent exacerbations of COPD lead to acute hypercapnic DN requiring NIV. In 30% of patients with severe exacerbation of COPD, NIV does not lead to the desired results. To optimize NIV in this group of patients, we used inhalations of thermal heliox (t-He/O2) and nitric oxide (iNO), which significantly improved O2 transport, CO2 elimination, hemodynamics and stabilized lactate levels.
FUNCTIONAL MAGNETIC RESONANCE TOMOGRAPHY IN STUDYING THE INFLUENCE OF THERMOHELIOX ON HEMODYNAMICS OF THE HUMAN CEREBRAL CORTEX EXCITED BY THE VISUAL STIMULUS
Authors: Semenova N. , Ublinskiy М. , Akhadov Т. , Bykov V. , Panin А. , Tsybenova S. , Varfolomeev S.
Published: November 2021

Using functional magnetic resonance imaging, it was shown that inhalation with thermogeliox changes the time dependence of the BOLD response to a visual stimulus. The resulting change in the duration of hemodynamic response caused by slowing down of the process of vasoconstriction of vessels in excitement.
DIAGNOSTIC TRAINING SENSOR SYSTEMS FOR PERSONALIZED CONTROL OF OXYGEN STATUS OF HUMAN TISSUE TISSUE
Authors: Mazing M.S. , Avdyushenko S.A.
Published: November 2021

An optical sensor system for the analysis of the integral oxygen status of human tissues has been developed and investigated on the basis of information technologies for training and pattern recognition.
ANTIBIOFILM ACTIVITY OF Β-HAIPRIN ANTIMICROBIAL PEPTIDES FROM MARINE POLYCHAETA
Authors: Panteleev P.V. , Ovchinnikova T.V.
Published: November 2021

Recombinant β-hairpin antimicrobial peptides were obtained from marine polychaeta Capitella teleta and Abarenicola pacifica, and their antibiofilm activity was studied.
INDUCTION OF T-CELL IMMUNE RESPONSE BY A RECOMBINANT STRAIN OF VACCINIA VIRUS EXPRESSING A CASSETTE OF STRUCTURAL PROTEIN'S GENES OF MARBURG VIRUS
Authors: Grazhdantseva A.A. , Antonets D.V. , Karpenko L.I. , Starostina E.V. , Borgoyakova M.B. , Kochneva G.V.
Published: November 2021

The constructed recombinant strain MVA-GP-VP40-MARV, in addition to the induction of humoral immunity, also forms specific cellular immunity to the Marburg virus, and therefore can be considered as a promising vaccine against Marburg fever.
ABILITY OF AURICULARIA AURICULAR-JUDAE EXTRACT TO SUPPRESS INFLUENZA VIRUS REPRODUCTION
Authors: Potekhina A. , Alexyuk P.G. , Zaitseva I.A. , Sokolova N.S. , Omirtayeva E.S. , Alexyuk M.S. , Bogoyavlenskiy A.P. , Berezin V.E.
Published: November 2021

The ability of the Auricularia auricular-judae extract to suppress the reproduction of the influenza virus was studied. It was shown that the index of the therapeutic activity of the extract is comparable to that of commercial preparations Tamiflu and Remantadine.
IMPLANTED MATERIALS BASED ON MODIFIED PECTINS FOR BIOENGINEERING NERVE TISSUE RECONSTRUCTION
Authors: Shved N.A. , Kuzyakova O.Yu. , Vitkalova A.V. , Kovalev V.V. , Malykin G.V. , Dyuizen I.V. , Kumeiko V.V.
Published: November 2021

The structure and properties of implanted materials based on modified pectins have been investigated, and the proposed mechanism of their action on the cells of the nervous tissue has been shown.
POINT-OF-CARE (POC) DEVICES – A NEW TREND IN BIOMEDICAL DEVICE
Authors: Rudnitskaya G.E. , Lukashenko T.A. , Evstrapov A.A.
Published: November 2021

Microchip devices made of glass, silicon, polymeric materials have been designed and tested for use in Point-of- Care diagnostic systems for biomedical purposes.
RECONSTRUCTION OF EVOLUTION OF GENOME STRUCTURES WITH PARALOGS
Authors: Gorbunov K.Yu.
Published: November 2021

For any weighted directed chain-cycle graphs a and b (referred to as structures) and any equal costs of operations (intermergings and duplication), we obtain an algorithm which, by successively applying these operations to a, outputs b if the first structure contains no paralogs (edges with a repeated name) and the second has no more than two paralogs for each edge. The algorithm has a multiplicative error of at most 13/9 + ε, where ε is any strictly positive number, and its runtime is of the order of no(ε–2.6), where n is the size of the initial pair of graphs. We also obtain algorithms for reconstruction of the evolution of genome structures with a condition on ancestor structures and along the phylogenetic tree.
DEVELOPMENT OF FLUORESCENCE POLARIZATION IMMUNOASSAY OF PHTHALATES: COMPARISON OF DIFFERENT DERIVATIVES IN OBTAINING ANTIBODIES AND TRACERS
Authors: Shanin I.A. , Karimova M.R. , Mukhametova L.I.
Published: November 2021

Reagents for fluorescence polarization immunoassay (FPIA) of phthalates have been obtained: phthalate-protein conjugates, polyclonal antibodies, tracers - antigens labeled with fluorescein derivatives. By the example of dibutyl phthalate (DBP) with the use of a portable detector Sentry-200, the FPIA method was developed, which makes it possible to determine DBP in water samples in concentrations 1 μg / ml in 5 min.
HIGHLY SENSITIVE IMMUNOASSAY OF PENICILLINS IN DAIRY AND MEAT PRODUCTS
Authors: Zilberman A.I. , Vashkevich I.I. , Sviridov O.V.
Published: November 2021

Specific immunoreagents have been obtained and a direct enzyme-linked immunosorbent assay with a very high sensitivity to penicillins in standard solutions (0.06 ng/ml) as well as in the samples of milk (0.3 μg/kg) and meat (2.4 μg/kg) has been developed.
MONITORING OF BIOLOGICAL ACTIVITY OF BETA-LACTAM ANTIBIOTICS RECEPTOR BLAR-CTD IN THE PROCESSES OF ITS HETEROLOGICAL EXPRESSION, PURIFICATION AND APPLICATION IN ANALYTICAL SYSTEMS
Authors: Semizhon P.A. , Scheslenok H.P. , Harbachova I.V. , Vashkevich I.I. , Sviridov O.V.
Published: November 2021

To develop the technologies of beta-lactam antibiotics bioassays in foods, high purity beta-lactam receptor BlaR-CTD has been obtained and characterized. A test system for the quantitation of the biologically active and immunoreactive receptor in the processes of its heterological expression, isolation and reagent forms preparation was elaborated. The immunochemical properties and antibiotic binding ability of BlaR-CTD were investigated, and the constructions and application procedures of receptor-immune systems for the assay of beta-lactam antibiotics using microplates or chromatographic test-strips were proposed.
RESEARCH OF PHYSICAL AND MECHANICAL PROPERTIES OF COMPOSITE MATERIALS BASED ON BACTERIAL CELLULOSE AND СЕО2
Authors: Revin V.V. , Rusyaeva V.V. , Starostina O.I.
Published: November 2021

This work is aimed at obtaining smart materials with improved functional characteristics for biomedical applications.
MODERN BIOCATALYTIC TECHNOLOGIES FOR PROTECTIVE MATERIALS AGAINST BIOLOGICAL AND CHEMICAL AGENTS
Authors: Zavyalova N.V. , Zavyalov V.V. , Gorelenkov V.K. , Frolov G.A. , Stepanov N.A. , Aslanli A.G. , Efremenko E.N.
Published: November 2021

Modern innovative approaches which can be applied to obtain universal protective materials with a wide spectrum of action are analyzed.
BIOCATALYTIC TECHNOLOGIES IN CONSTRUCTION AND HOUSING AND COMMUNAL SERVICES: APPLICATION AND PROSPECTS
Authors: Pustovgar A.P.
Published: November 2021

This paper describes the use of biocatalytic technologies in construction and housing and communal services. Special attention is paid to the use of microbiological processes for the modification of soil bases, concretes and building mortars. The problems and directions of future research in this area are considered.
PRECLINICAL STUDIES TO ASSESS ACUTE AND CHRONIC TOXICITIES OF A CANDIDATE DRUG BASED ON COMPLEMENT C3 NEODETERMINANT RECOMBINANT HUMANIZED ANTIBODY FOR TREATMENT OF TRAUMATIC
BRAIN INJURIES
Authors: Trofimov A.V. , Zhakhov A.V. , Rodin S.V. , Gorbunov N.P. , Petrov A.V. , Pigareva N.V. , Aleksandrov G.V. , Zakharov M.S. , Kiryanova А.S. , Khuttunen О.E. , Bendt I.V. , Krylova A.E. , Ischenko A.M.
Published: November 2021

A drug based on complement C3 neodeterminant recombinant humanized antibody for the treatment of traumatic brain injuries belongs to the class III of low-risk drugs.
EVOLUTION OF THE LIPID COMPOSITION OF THE HUMAN BRAIN
Authors: Stekolshchikova Е.А. , Tkachev А.I. , Osetrova М.S. , Smirnov D.N. , Efimova О.I.
Published: November 2021

We measured lipid composition for 33 regions of the brain, covering all basic brain structures in healthy humans, chimpanzees, bonobos, and macaques. This analysis allows us to identify features of lipidomes of functionally divergent brain regions that are unique to humans.
DETERMINATION OF LIGANDS SPECIFIC TO MACROPHAGE MANNOSE RECEPTORS USING COMPUTER MODELING AND SPECTRAL METHODS
Authors: Kudryashova E.V.
Published: November 2021

Computer simulations have shown that concanavalin A lectin is a relevant model of macrophage mannose receptors. Optimal parameters of modification of the drug carrier β-cyclodextrin were determined: a high degree of mannosylation (it is enough to use simple mannose) - from 60%, the presence of spacers. Such molecules form a strong complex with the concanavalin receptor: Kd from 0.8 to 2.2 μM.
GENOME EDITING FOR THE DEVELOPMENT OF ETIOTROPIC THERAPY OF HEREDITARY DISEASES
Authors: Smirnikhina S.A.
Published: November 2021

Genome editing techniques could be used as gene therapy for hereditary diseases. Clinical trials are already underway for at least seven of them, and several dozen drugs are at the preclinical stage of research.
APPLICATION OF NEUROTROPHIC FACTORS BDNF AND NT-3 IN CELL THERAPY OF EXPERIMENTAL POSTTRAUMATIC SPINAL CORD CYSTS
Authors: Voronova A.D. , Chadin A.V. , Fursa G.A. , Karsuntseva E.K. , Valikhov M.P. , Semkina A.S. , Reshetov I.V. , Chekhonin V.P.
Published: November 2021

The experimental post-traumatic spinal cord cysts were modeled. It has been shown that NT-3 enhances the effectiveness of the use of human olfactory ensheathing cells in the treatment of experimental spinal cord cysts.
SEARCH AND CHARACTERIZATION OF ELECTRONOACEPTORS FOR L-GALACTONE-1,4-LACTONE DEHYDROGENASE FROM ARABIDOPSIS THALIANA
Authors: Kudryashova E.V.
Published: November 2021

Natural (cytochrome C) and artificial electron acceptors (1,4-benzoquinone, phenazine methosulfate, tetramethylphenylenediamine) were characterized, and the possibility of using the acceptors to determine the enzymatic activity of L-galactone-1,4-lactone dehydrogenase of Arabidopsis Thaliana in an aqueous solution and in a micellar system was investigated.
NANOMECHANICAL PROPERTIES OF GLIOMA CELLS WITH IDH1 R132H MUTATION IN PRIMARY CULTURES AS PROSPECTIVE MARKERS FOR ONCODIAGNOSTICS
Authors: Gulaya V.S. , Romanishin A.O. , Farniev V.M. , Shved N.A. , Kumeiko V.V.
Published: November 2021

Phenotyping and genotyping of tumor cells of various genesis provides irreplaceable information for targeted therapy. We have revealed the nanomechanical properties of living cells of cultures of primary cell lines of gliomas with the IDH1 R132H mutation, which make it possible to differentiate them from cells that do not have this mutation, which is necessary for personalized therapy of these diseases.
Vulnerabilidad de la caficultura del Norte de Santander a la broca del café en diferentes eventos climáticos
Authors: Giraldo-Jaramillo Marisol , Montoya Esther Cecilia , Sarmiento-Herrera Ninibeth , Quiroga Mosquera Audberto , Espinosa-Osorio Juan Camilo , García-López Juan Carlos , Duque Orrego Hernando , Benavides Machado Pablo
Published: November 2021

Conocer la vulnerabilidad de una zona a la broca de café, teniendo claro que es una condición natural de esta y que, bajo ciertos escenarios climáticos, la plaga puede comportarse de una forma esperada, es una ventaja competitiva clara para los caficultores, pues podrán anticipar muchas decisiones de manejo. En este Avance Técnico consulte la vulnerabilidad del departamento de Norte de Santander a la broca del café en diferentes escenarios climáticos, Neutro, La Niña y El Niño.
X-Rays from V723 Mon are due to Optical Loading in Swift XRT
Authors: Hare Jeremy , Kargaltsev Oleg , Cenko S. Bradley , Klingler Noel J.
Published: November 2021

V723 Mon was recently reported to be hosting the nearest (d = 460 pc) candidate black hole by Jayasinghe et al. An X-ray detection was claimed based on deep Swift XRT observations with a luminosity of L
X ≈ 8 × 1029 erg s−1 or L
X/L
Edd ≈ 10−9. Here we show that the X-ray photons detected by Swift XRT are due to optical loading from the bright (V = 8.3 mag) star. Using events in the 2–10 keV energy band, where optical loading does not strongly contribute, we find a 3σ upper-limit on the unabsorbed 2–10 keV X-ray flux of F
X < 2.8 × 10−14 erg cm−2 s−1, corresponding to a luminosity L
X < 7.2 × 1029 erg s−1 at a distance of 460 pc or L
X/L
Edd ≲ 2 × 10−9 for a M ≈ 3M
⊙ black hole.
Écriture et forme scolaire : spécificités de transcription et de traitement
Authors: Doquet Claire , Revelli Luisa , Moysan Arnaud
Published: November 2021

Cet article examine les manières de donner à voir les écrits scolaires en respectant leur sémiotique propre, fondée à la fois sur la spatialisation et sur la stratigraphie de l’écriture. À partir des travaux de sémiotique et de génétique textuelle, il explicite les choix de transcription et de traitement opérés dans deux bases d’écrits d’élèves existantes, l’une française et l’autre italienne, pour étudier les transformations que les spécificités et les conventions de l’écriture scolaire imposent aux méthodes forgées sur d’autres écrits.
Productivistes contre écologistes
Authors: Boy Daniel
Published: November 2021

La question de la croissance industrielle et de ses conséquences parfois dommageables constitue depuis longtemps un motif de disputes idéologiques. Toutefois, jusqu’aux années 1970, elle n’a pas véritablement généré de clivage majeur dans le champ partisan. L’émergence de l’écologie politique de la décennie suivante a, pour la première fois, institué un espace de controverses sur le thème de la croissance. Pour un temps, les écologistes ont conservé le monopole d’une remise en question du productivisme. Désormais, plus un seul parti ne peut ignorer les questions que pose la prégnance des enjeux climatiques. Si nulle formation politique ne se prétend opposée à toute croissance, aucune non plus ne défend une croissance sans condition.
Construction of competitive endogenous RNA network related to circular RNA and prognostic nomogram model in lung adenocarcinoma
Authors: Song Pingping ,   School of Mathematics and Statistics, Southwest University, Chongqing 400715, China, Chen Jing , Zhang Xu , Yin Xiaofeng ,   School of Science, Southwest University of Science and Technology, Sichuan 621000, China
Published: November 2021

Early researches have revealed that circular RNA (circRNA) had the potential of biomarkers and could affect tumor progression through regulatory networks. However, few research focused on the function of circRNA in lung adenocarcinoma and the regulation mechanism of competitive endogenous RNA. In present study, through differential expression analysis, 10 circRNAs, 98 miRNAs(microRNA) and 2497 mRNAs were screened. Based on the 10 circRNAs and related databases, a competitive endogenous RNA regulatory network (ceRNA network) containing 7 circRNAs, 13 miRNAs and 147 mRNAs was constructed. KEGG and GO analysis suggested that 147 mRNAs were obviously enriched in biological pathway related to LUAD. By constructing a PPI network, 12 hub genes were identified by MCODE. The result of survival analysis showed that 10 hub genes (BIRC5, MKI67, CENPF, RRM2, BUB1, MELK, CEP55, CDK1, NEK2, TOP2A) were significantly related to the survival of LUAD. We randomly divided 483 clinical data into two parts: train set and validation set. The train set was used for Cox regression analysis, 3 prognostic factors (stage, T, CDK1) were screened. The nomogram model was constructed based on stage, T and CDK1. The model was evaluated by ROC curve, calibration chart, Kaplan-Meier (KM) curve and validation set data. The results indicated that the model has good accuracy. Our study elucidated the regulatory mechanism of circRNA in lung adenocarcinoma, and the nomogram model also provided insight for the clinical analysis of lung adenocarcinoma.
Offrandes alimentaires en Italie du Sud : le témoignage des terres cuites en milieu funéraire
Authors: Meirano Valeria
Published: November 2021

Dans le monde grec ainsi que dans les contextes indigènes de l’Italie méridionale, la coroplathie joue un rôle dans le rituel funéraire, soit dans la composition des mobiliers, soit au cours des cérémonies qui avaient lieu durant et après l’enterrement. Malgré leur occurrence limitée dans la majorité des nécropoles par rapport à d’autres offrandes, plusieurs recherches récentes ont mis en évidence la façon dont ces objets contribuaient à la « construction » de l’identité du défunt, surtout en relation avec le genre et les classes d’âge. Parmi ces artefacts, les reliefs et les figurines portant des offrandes alimentaires, ainsi que les petits modèles reproduisant des aliments, constituent un sujet d’étude à part entière. Associée aux données relevant des realia et à d’autres sources documentaires – telles que les textes littéraires et épigraphiques, l’iconographie véhiculée par la céramique figurée, etc. –, l’étude de ces objets contribue à éclairer un aspect important de l’univers lié à la mort, grâce aussi à la comparaison avec la « nourriture symbolique » attestée dans les espaces sacrés. L’article propose quelques réflexions sur la présence de ces terres cuites dans les nécropoles grecques et indigènes de l’Italie du Sud, visant à saisir la façon dont ces offrandes participaient de la stratégie funéraire et de la performance rituelle, ainsi que les différentes valeurs revêtues selon leurs contextes spécifiques.
À propos de deux vases inscrits du Louvre. À la recherche d’une pharmacopée étrusque
Authors: Briquel Dominique , Frère Dominique
Published: November 2021

Le musée du Louvre possède deux petits vases globulaires sans anses à col allongé, issus de la collection Campana et provenant vraisemblablement des fouilles entreprises par le marquis sur le site de Cerveteri, portant inscrits l’un le terme CUPRUM, l’autre le terme RUTA. Ces deux inscriptions ont été parfois attribuées à l’osque, souvent considérées comme fausses, tandis que les vases étaient datés d’une période tardive. Mais le caractère étrusque de ces documents ne fait pas de doute, leur authenticité ne paraît pas contestable, les vases – même s’ils relèvent d’une catégorie de céramique encore mal étudiée – remontent à l’époque archaïque. Les mots cuprum et ruta sont donc à considérer comme étrusques mais sont des mots d’emprunt, transcrivant les dénominations grecques du henné et de la rue. Ces deux vases ont dû contenir des produits liquides ayant pour base ces deux plantes. Des analyses biomoléculaires, menées en novembre 2011 dans le cadre du programme Perhamo/MAGI, ont permis d’apporter quelques précisions sur les contenus de ces vases. Ils sont formés d’une base grasse composée, pour l’un, de graisse animale (celui avec inscription RUTA) et, pour l’autre, d’huile végétale (avec un produit laitier et de l’oléorésine de conifère). La rue représentait le principe actif d’un liniment tandis que le henné a sans doute servi à la fabrication d’une huile médicinale faisant office d’embrocation. On s’interrogera ici sur la signification de ces deux produits, connus pour leur usage médicinal, dans la tombe où ils avaient été placés – puisqu’il est hors de doute que les deux vases ont été trouvés dans une tombe et, de facture identique, ont appartenu à un même mobilier funéraire.
Du miel aux cendres. Pour une archéologie du miel étrusque
Authors: Jolivet Vincent
Published: November 2021

Les tombes étrusques du début de la période hellénistique ont livré, pour l’essentiel à Tarquinia et dans son territoire, une centaine d’exemplaires d’un récipient de forme inusitée, caractérisé par une large collerette placée au-dessus de l’épaulement du vase. Bien que cette forme ait généralement été interprétée comme une urne cinéraire, à partir de différents exemplaires effectivement utilisés à cette fin, il s’agit probablement dans tous les cas d’une utilisation secondaire, comme le montre l’absence de tout couvercle correspondant dans les tombes. Les parallèles ethno-archéologiques effectués avec des formes très semblables utilisées encore aujourd’hui en Crète et dans la péninsule ibérique, où la forme a été produite depuis l’Antiquité, invitent à penser qu’il s’agissait de vases à miel, la collerette étant destinée à être remplie d’eau pour protéger le contenu du vases des insectes rampants. Il s’agirait là du premier témoignage concret d’une activité d’apiculture en Étrurie où l’on n’a pas, à ce jour, identifié de ruches. Il est possible que le choix de ce type de récipient comme urne funéraire ait été suggéré par les valeurs de luxe et d’immortalité traditionnellement associées au miel dans le monde hellénistique.
Riti alimentari nella Sardegna punica: il caso di Pani Loriga
Authors: Botto Massimo , Frère Dominique , Garnier Nicolas , Madrigali Emanuele
Published: November 2021

Scopo del seguente contributo è quello di presentare alla comunità scientifica internazionale i risultati delle recenti indagini all’abitato punico di Pani Loriga, nella Sardegna sud-occidentale. Gli scavi avviati dal CNR sul versante settentrionale della collina hanno messo in luce un grande edificio polifunzionale composto da oltre dieci vani, il cui impianto originale risale alla fine del VI-inizi del V sec. a.C. La struttura, ancora in corso di scavo, presenta alcune situazioni particolarmente pertinenti alle tematiche affrontate nell’ambito del Convegno MAGI. Infatti, nel vano 7, è stato messo in luce una specie di pozzetto chiuso da una lastra di scisto, sul fondo del quale sono state rinvenute ossa animali e un ritaglio di piombo pertinenti molto verosimilmente ad un rituale di fondazione. Le ossa sono state disposte con cura all’interno della struttura e grazie all’analisi di Jacopo De Grossi è possibile affermare che si tratta di parti selezionate di diverse specie animali: sono documentati gli ovicaprini, il bue e il cervo. Nel vano 1, interpretato come un sacello, alla base della banchina sulla quale dovevano essere deposti gli ex voto sono state recuperate ossa animali pertinenti a sacrifici o a resti di pasto. De Grossi ha individuato resti di ovicaprini, bue, maiale e cervo. Questi dati possono essere integrati con quelli relativi alle analisi biochimiche condotte da Nicolas Garnier sui contenuti di numerosi vasi rinvenuti nell’attiguo vano 2, dove molto verosimilmente dovevano essere confezionati cibi e bevande da consumare nel corso di cerimonie pubbliche.
Des professionnels qui s’agitent dans l’effervescence du Grand Paris
Authors: Vu Hélène Dang , Gomes Pedro
Published: November 2021

Sept-cents projets d’urbanisme sont engagés dans la zone dense du Grand Paris. Devant cette effervescence, ce n’est pas que le territoire qui se transforme mais aussi les acteurs et leurs pratiques ainsi que les compétences professionnelles recherchées. Cet article revient sur le travail d’un collectif de recherche qui, pour capter et comprendre ces évolutions, a interviewé une douzaine de professionnels en position de direction dans différents milieux de l’aménagement. Leurs trajectoires et pratiques professionnelles et leurs points de vue sur les transformations en cours sont présentés sous la forme de quatre compétences majeures mises en œuvre et de cinq figures de professionnels, archétypes de l’aménagement de ce Grand Paris en effervescence.
Patrícia Moreira contra “noventa milhões em ação”? Racismo e antirracismo no futebol brasileiro
Authors: Mello Luciana Garcia
Published: November 2021

Nos últimos anos multiplicam-se os ataques racistas a jogadores de futebol, o que parece indicar a banalização do racismo. Esse fenômeno sempre foi um tabu, dificultando a sua percepção enquanto problema social e, consequentemente, a definição de estratégias para combatê-lo. A partir de um episódio envolvendo o goleiro Aranha, esse artigo tem por objetivo refletir em que medida esses casos que tiram a ideia de democracia racial da zona de conforto têm potencial para promover o antirracismo. Utilizou-se como objeto de análise o discurso de dois atores envolvidos no fato em questão – o Grêmio Futebol Porto Alegrense e a torcedora Patrícia Moreira, que tinham por meta, respectivamente, promover o antirracismo no futebol e esquivar-se da acusação de racismo. É possível afirmar que o antirracismo esbarra na desqualificação do racismo e no reforço da ideologia da mistura e da indistinção racial.
A presença de mulheres imigrantes e refugiadas no estado do Paraná: caracterização do fenômeno recente e elaboração de políticas públicas
Authors: Baltar Cláudia Siqueira , Baeninger Rosana
Published: November 2021

O presente trabalho tem como objetivo pesquisar a presença das mulheres imigrantes e refugiadas, no período recente, no estado do Paraná, articulada à análise do panorama das políticas migratórias e para mulheres, existentes em âmbito municipal. Em termos teóricos, considera-se a perspectiva da complexidade das migrações internacionais contemporâneas, a articulação entre migrações internacionais e gênero e os desafios na elaboração de políticas migratórias, em âmbito municipal. Em termos empíricos, são analisados os registros administrativos do Sistema de Registro Nacional Migratório (SISMIGRA), da Polícia Federal, e os microdados da Pesquisa de Informações Básicas Municipais (MUNIC), realizada pelo IBGE. O recorte espacial compreende microrregiões e municípios do estado do Paraná e o recorte temporal compreende o período 2010-2019. Busca-se contribuir para o debate teórico no campo dos estudos migratórios e reforçar a importância da sistematização e disponibilização de informações sobre as migrações internacionais contemporâneas e a elaboração de políticas públicas.
Certifications in Cybersecurity Workforce Development
Authors: Wang Ping , D'Cruze Hubert
Published: November 2021

The workforce demand for cybersecurity professionals has been substantial and fast growing. Qualified cybersecurity professionals with appropriate knowledge, skills, and abilities for various tasks and job roles are needed to perform the challenging work of defending the cyber space. The certified information systems security professional (CISSP) certification is a globally recognized premier cybersecurity credential and validation of qualifications. This case study analyzes the CISSP certification requirements, domains and objectives and attempts to map them to the cybersecurity industry competencies and the US national cybersecurity workforce framework (NCWF). This research is an extended study with full mapping of all CISSP domain areas to the knowledge, skills, and abilities in NCWF. The extended study aims to discover the in-depth value and role of reputable certifications such as CISSP in competency development for cybersecurity workforce. This article also discusses the value and implications of the CISSP certification on cybersecurity education and training.
Towards the Development of a Game for Computational Thinking
Authors: Kosmas Panagiotis , Philippou Andrea , Psomos Panagiotis
Published: November 2021

Computational thinking (CT) is now considered an essential approach for developing critical thinking and 21st-century skills. CT as a teaching methodological approach is more connected to STEM education as it provides clearer conceptual and practical considerations to understand science, computer, and mathematical concepts. Based on the recent literature, educational robotics, applications, and serious games are the means of applying CT in teaching practice. This study examines students' needs, interests, and motivations for using a game in the context of CT. Quantitative analysis from an online questionnaire to 394 students from secondary education in different five countries (Greece, Cyprus, Italy, Poland, United Kingdom) demonstrate the students' game interests and needs that guide us to develop a game for CT's implementation in the classroom. Essential insights, considerations, and implications are providing for the design, development, and use of games for the CT in an educational environment.
Recognizing the Physical Activity of Hospitalized Older People From Wearable Sensors Data Using IoT
Authors: Boukhalfa Siham , Amine Abdelmalek , Hamou Reda Mohamed
Published: November 2021

The IoT is a new concept that provides a world where smart, connected, embedded systems operate, giving rise to the amount of data from different sources that are considered to have highly useful and valuable information. Data mining would play a critical role in creating smarter IoT. Traditional care of an elderly person is a difficult and complex task. The need to have a caregiver with the elderly person almost all the time drains the human and financial resources of the health care system. The emergence of Artificial intelligence has allowed the conception of technical assistance where it helps and reduces the time spent by the caregiver with the elderly person. This work aims to focus on analyzing techniques that are used for prediction purposes of falls in the elderly. We examine the applicability of three classification algorithms for IoT data. These algorithms are analyzed and a comparative study is undertaken to find the classifier that performs the best analysis on the dataset using a set of predefined performance metrics to compare the results of each classifier.
New Discrete Crow Search Algorithm for Class Association Rule Mining
Authors: Hichem Haouassi , Rafik MEHDAOUI , Ouahiba Chouhal
Published: November 2021

Associative Classification (AC) or Class Association Rule (CAR) mining is a very efficient method for the classification problem. It can build comprehensible classification models in the form of a list of simple IF-THEN classification rules from the available data. In this paper, we present a new, and improved discrete version of the Crow Search Algorithm (CSA) called NDCSA-CAR to mine the Class Association Rules. The goal of this article is to improve the data classification accuracy and the simplicity of classifiers. The authors applied the proposed NDCSA-CAR algorithm on eleven benchmark dataset and compared its result with traditional algorithms and recent well known rule-based classification algorithms. The experimental results show that the proposed algorithm outperformed other rule-based approaches in all evaluated criteria.
Exploring K-3 Educator Perspectives on STEM Learning
Authors: Ntuli Esther , Ray Beverly B. , Ray Berverly B.
Published: November 2021

Science, technology, engineering, and mathematics (STEM) instruction has become a priority b across the globe in recent years. Elementary educators are seeking ways to integrate STEM in all areas of learning. However, research indicates that most elementary teachers grapple with identifying and using appropriate STEM tools and instructional strategies that teach STEM as an integrated subject. This paper reports on an exploratory study examining the experiences of K-3 teachers (n=26) who contributed to the development of a summer STEM institute. It also examines in greater detail the perceptions of twelve of those participants who participated in the professional development institute. The study used quantitative and qualitative approaches to collect and analyze data. Findings indicate that teachers appreciate the use of inexpensive STEM tools and that they recognize the potential that an integrated STEM project-based learning approach has for young students. Implications for teacher education and professional development are offered along with recommendations for future research.
Investigating K-12 Pre-Service Teacher TPACK in Instructional Technology Learning
Authors: Abebe Fitsum F. , Gaskill Martonia , Hansen Tommy , Liu Xianquan
Published: November 2021

This study investigated the change in pre-service teachers’ Technological Pedagogical Content Knowledge (TPACK) self-efficacy beliefs in a technology integration course in a teacher education program. It assessed knowledge components that predicted TPACK self-efficacy beliefs. Pre and post-surveys were administered using Schmidt et al. (2009) instrument at the beginning and end of the course. The study revealed statistically significant change in all dimensions of TPACK self-efficacy beliefs. Cohen’s effect size revealed medium effect size on TPACK self-efficacy beliefs during the pre-service teacher education technology integration course. PCK and TPK were the significant predictors of TPACK in both pre and post-survey report. Content Knowledge (CK) was a significant predictor of TPACK in the post-survey. The result implies that instructional technology courses should pay attention to the factors affecting TPACK during curriculum design and course delivery. In the current research context CK, PCK and TPK predicted TPACK. TK and PK can be mediated by TPK and PCK respectively.
Developing a Framework for Electronic Engagement at Work
Authors: Gupta Manish , Jain Aman , Nayak Niladri Bihari , Kumar Anil , Behl Abhishek
Published: November 2021

Several electronic-engagement-related questions arise at work due to the beginning of a new era of social distancing, lockdowns, quarantining, and sanitization. These terms were not so common before. What challenges do employees face while working from home? Why do they face those challenges? How are they overcoming these challenges? In summary, in a work-from-home setting, what are the issues and solutions in engaging remote workers electronically? To answer these questions, 23 Information Technology (IT) employees in India and four in the United Kingdom were interviewed, and data were analyzed using interpretive phenomenological analysis (IPA). Few Information Technology employees from the United Kingdom were also interviewed to ensure the transferability of the results. Along with a few suggestions, six challenges emerged. These may help employers formulate their electronic engagement strategies for employees in a better manner.
Reproduction and fecundity of invader of internal insemination Trachelyopterus galeatus in a Neotropical floodplain
Authors: Schmidt Amanda Borges dos Santos , Pereira Vanessa de Brito , Antunes Arthur Henrique de Sousa , Bernardes Ana Luiza Faria , Santana Herick Soares de , Tos Claudenice Dei
Published: November 2021

After the formation of Itaipu Reservoir, the invader Trachelyopterus galeatus colonized the upper Paraná River. Light microscopy was used to describe gametogenesis and the reproductive phases of females and males. The following data were verified: diameter of the oocytes, spawning type, batch fecundity by ovary weight, standard length, and total weight of the fish, along with the regions where this species reproduced in the upper Paraná River floodplain. A total of 470 specimens were collected quarterly in 2016, 2018 and 2019, and bimonthly in 2017. The gonads were fixed in a Karnovsky solution, dehydrated, infiltrated, and embedded in historesin. The histological slides were stained using PAS + iron hematoxylin + metanil yellow, analyzed and photographed under an image-capturing microscope. As regards diameter of the oocytes and fecundity estimates, ovaries whose oocytes were measured under a stereomicroscope were sampled. In the oogenesis, undifferentiated and differentiated oogonia, early primary growth oocytes, secondary growth oocytes, full-grown oocytes and maturing oocytes were recorded. In the spermatogenesis, primary and secondary spermatogonia, primary and secondary spermatocytes, spermatids and spermatozoa were recorded. The reproductive phases found for females and males were: immature, early development, late development, spawning/sperm-releasing capable, regression, and regeneration. Trachelyopterus galeatus prefers to occupy and reproduce in the Ventura, Patos, Guaraná, Fechada, Garças, and Pau Véio lagoons. The diameter of the oocytes varied from 0.4 to 2.9 mm. Females spawn, on average, 113 oocytes per batch. Batch fecundity variation shows that the larger the ovary, standard length, and total weight, the larger the number of oocytes to be spawned. This invader possesses reproductive success in the upper Paraná River floodplain, especially in lagoons.
Enhancement of antioxidant properties of Triticum durum obtained by traditional spontaneous fermentation in underground silos
Authors: Benhamada Nabila , Idoui Tayeb
Published: November 2021

Fermented foods have made important contributions to human diets for thousands of years and continue to do so. Their health-promoting benefits are attracting increasingly attention. The present study was conducted to evaluate the impact of natural fermentation on antioxidant properties of traditionally fermented wheat (Triticum durum) compared to unfermented samples. Initially, the samples were submitted to traditional spontaneous fermentation. Subsequently, an aqueous extract was obtained and used to determine polyphenolic and flavonoid contents. Moreover, the antioxidant potential was also measured through the determination of the scavenging ability against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, reducing power and hydrogen peroxide scavenging activity. The results showed that the total phenolic and total flavonoid contents were significantly increased in fermented wheat. Moreover, the antioxidant activity was more effective in fermented than in unfermented wheat. Thus, natural fermentation can enhance natural antioxidants in wheat and transform it into a healthy food or ingredient with multi-functional properties which can be used in the food industry.
Para compreender a proposta de alfabetização: o livro didático para o primeiro ano do ensino fundamental em foco
Authors: Freitas Vinícius Adriano de , Galuch Maria Terezinha Bellanda
Published: November 2021

Fundamentando-se na Teoria Crítica da Sociedade, este artigo tem como objetivo compreender a relação entre os encaminhamentos dados ao ensino e à aprendizagem inicial da língua escrita e a proposta de formação cultural para crianças em processo de alfabetização. Os dados foram coletados no livro didático ‘Aprender juntos: letramento e alfabetização’, destinado ao componente curricular letramento e alfabetização para o primeiro ano do ensino fundamental. As análises apontam que a proposta apresentada prioriza situações de vivência do uso social da leitura e da escrita, com poucas atividades voltadas ao estudo explícito das habilidades de ler e de escrever quaisquer palavras, frases ou textos. Apesar de este encaminhamento se pautar na ideia da necessidade de formar o sujeito crítico, ao enfatizar a forma (no dualismo forma e conteúdo), acaba concorrendo para a formação cuja ênfase é a adaptação à realidade vigente, portanto concorre para a pseudoformação.
Respiratory mechanics behavior after heart surgery: an experimental study
Authors: Lima Francisco José Nascimento , Avena Katia de Miranda , Duarte Helder  Brito , Mendes Kristine Menezes Barberino , Gomes Yasmin Silva , Feijó Luciana Ferreira , Olivieri Flávia Milholo
Published: November 2021

Changes in ventilatory mechanics and their consequent pulmonary complications are common after surgical procedures, particularly in cardiac surgery (CS), and may be associated with both preoperative history and surgical circumstances. This study aims to compare ventilatory mechanics in the moments before and after cardiac surgery (CS), describing how pulmonary complications occurred. An experimental, uncontrolled study was conducted, of the before-and-after type, and with a descriptive and analytical character. It was carried out in a private hospital in the city of Salvador, Bahia, Brazil, and involved 30 adult patients subjected to CS. In addition to clinical and epidemiological variables, minute volume (VE), respiratory rate (RR), tidal volume (VT), forced vital capacity (FVC), maximum inspiratory pressure (MIP), and peak expiratory flow (PEF) were also recorded. Data were collected in the following moments: preoperative (PRE-OP) period, immediate postoperative (IPO) period, and 1st postoperative day (1st POD). The sample was aged 48.1 ± 11.8 years old and had a body mass index of 25.5 ± 4.9 kg m-2; 60% of the patients remained on mechanical ventilation for less than 24 hours (17.5 [8.7-22.9] hours).  There was a significant reduction in VT, FVC, MIP and PEF when PRE-OP versus IPO, and PRE-OP versus 1st POD were compared (p < 0.05). There were no significant changes between IPO and the 1st POD. The highest incidence of pulmonary complications involved pleural effusion (50% of the patients). This study showed that patients subjected to CS present significant damage to ventilatory parameters after the surgery, especially in the IPO period and on the 1st POD. It is possible that the extension of this ventilatory impairment has led to the onset of postoperative pulmonary complications.
Retrospective study of polytrauma patients’s medical records that presented abdominal trauma, comperad to abdominal trauma and extra-abdominal injuries
Authors: Coutinho Izadora Gabriela , Crema Thiago Henriqque , Petta Bruno Felipe Viotto , Fontes Carlos Edmundo  Rodrigues
Published: November 2021

This study sought to retrospectively assess the relationship between intra and extra-abdominal injuries in polytrauma patients undergoing laparotomy at the Regional University Hospital of Maringá between 2017 and 2018.This study was based on 111 electronic medical records from the Brazilian public health system “SUS”, admitted to the hospital due to trauma and undergoing laparotomy, comparing two groups: abdominal injury without extra-abdominal injury (WoEI) and abdominal injury with extra-abdominal injury (WiEI).A total of 111 medical records were analyzed, 57 from 2017 and 54 from 2018. Of these 111records, 43 (39%) were trauma victims with only abdominal injuries and 68 (61%) trauma victims with abdominal and extra-abdominalinjuries. Most patients were male (85%), with an average age of 33 years, ranging from 14 to 87 years. In statistical analysis, according to the T-test, there was significance (p > 0.05) between the WoEI and WiEI groups for data collected regarding death rates and hospitalization days. As for the morbidity rate and difference between genders (male and female), there was no statistical significance (p < 0.05). Polytrauma patients are exposed to greater kinetic energy, with more severe conditions and therefore required more in-hospital care.
Plant growth-promoting activity of wild-type and bromate-resistant mutant of the endophytic fungus Colletotrichum karstii
Authors: Oliveira João Arthur dos Santos , Ferreira Ana Paula , Polli Andressa Domingos , Silva Angela Aparecida da , Ribeiro Amanda da Silva , Azevedo João Lúcio , Pamphile João Alencar
Published: November 2021

Endophytes may play important roles in agriculture. Spontaneous or induced mutant strains may increase their biotechnological properties. Seventeen Colletotrichum endophytic fungi were investigated for their plant growth-promoting characteristics (in vitro phosphate solubilization, IAA, and siderophore production). The five best strains were inoculated into bean seeds, and the most prominent isolate was selected to obtain auxotrophic mutants by Potassium Bromate Resistance System (PBRS). The plant growth-promoting ability of the mutant was also investigated. Further, 41.17% of the evaluated endophytes presented promising results for in vitro assays (C. karstii SL10, C. karstii SL28, C. karstii SL57, C. karstii SL59, C. karstii SL12, C. karstii SL40, and C. karstii SL24). The endophyte C. karstii SL57 was statistically conspicuous for plant height and root length when compared to those in control plants. Bromate-resistant mutant C. karstii SL57 increased in vitro phosphate solubilization (23%) and chlorophyll levels (Chlb 0.607 mg g-1 and Chlt 0.973 mg g-1) of bean plants when compared to the wild-type strain (Chlb 0.551 mg g-1 and Chlt 0.881 mg g-1). This is the first time an auxotrophic mutant fungus has been obtained by PBRS with a biotechnological application for the agricultural field
Customer Acceptance and Service Continuation Intention of the Touch Travel Pass Terminals in Sri Lanka
Authors: Lakmal D.N.E.
Published: November 2021

The Touch travel pass system is introduced to the Sri Lankan market with the intention of automating the traditional bus ticketing mechanism. After five years of the product introduction, it is revealed that there are less acceptance and service continuation intention amongst the terminal users. Hence, the purpose of this study is to investigate the determinants of customer acceptance and service continuation intention of touch travel pass terminals in Sri Lanka. This study employs a quantitative methodology and survey strategy. Primary data was gathered from a sample of 150 bus owners and 150 bus conductors using a structured questionnaire utilizing a systematic random sampling technique. The theoretical framework and hypotheses were developed based on previous literature. The independent sample t-tests, one-way ANOVA, and multiple regression models were used through SPSS software in testing the hypotheses. Perceived usefulness, social influence, and trust show a significant positive impact on customer acceptance. Trust shows a higher impact on customer acceptance than the other determinants. Further, the findings disclose that demographic factors such as gender, age, marital status, and education do not show any significant impact on customer acceptance and service continuation. Moreover, it is implied that the perceived usefulness, perceived ease of use and government influence have a significant impact on service continuation intention. Government influence shows a higher impact on service continuation intention than the other determinants. The management should focus more on perceived trust, social influence and perceived usefulness in enhancing customer acceptance. Further, the marketers should focus more on perceived usefulness, ease of use, and government influence in enhancing the service continuation. Moreover, the government should also focus on developing a mandatory requirement for the use of travel pass for the enhancement of both customer acceptance and the service continuation. Further, the government should develop the necessary infrastructure facilities to smoothen the process. This study is the first to investigate the factors affecting customer acceptance and service continuation of touch travel pass terminals in the Sri Lankan context.
Impact of Firm-Specific News Releases on Share Prices in Bank, Finance and Insurance Sectors of Colombo Stock Exchange
Authors: Banda Y.K. Weerakoon , Yeshani G.G.S.
Published: November 2021

This paper examines the impact of firm-specific news releases on share price changes in bank, finance, and insurance sectors of the Sri Lankan stock market: Colombo Stock Exchange (CSE). The data is gathered from the CSE data base and annual reports for the daily share prices, All Share Price Index (ASPI), and news releases for the period from January 2017 to December 2018. Two types of analysis were performed to identify the impact of firm-specific news releases on share prices, namely an individual company level analysis and industry level analysis. The findings of both the analysis indicate that relationship between firm specific information releases and changes in share prices is statistically insignificant except for dividend announcements. Further, research in this area is needed to substantiate the findings of this study using subcategories of the firm specific news releases.