bluuebunny/crossref_metadata_2025 huggingface dataset:
Cumulative Effects of Prenatal and Concurrent Maternal Distress
on Psychiatric Disorders in Adolescent Offspring
Authors: Mortaji Neda , Savoy Calan , Boylan Khrista , Amani Bahar , Lieshout Ryan J Van
Published: November 2021

Background:

Mental disorders affect 20% of children and adolescents
globally and are among the most chronic and costly problems affecting youth.
Offspring exposure to maternal disorders (depression, anxiety, and/or stress)
prenatally as well as in adolescence increases the risk of psychopathology in
adolescence.

Objective:

Exposure to maternal distress in pregnancy, as well as in adolescence,
has independently been linked to psychopathology in youth. However, our
understanding of the cumulative effects of exposure to maternal distress over time
remains incomplete.

Methods:

1964 participants enrolled in the 2014 Ontario Child Health Study
(OCHS) aged 12-17 years completed the Mini-International Neuropsychiatric
Interview for Children and Adolescents (MINI-KID). Maternal prenatal distress
was defined as mother-reported depression and/or anxiety during pregnancy
requiring treatment. Maternal concurrent distress was self-reported when offspring
were 12-17 years of age using the Kessler Psychological Distress Scale (K6). We
examined associations between increasing levels of exposure to maternal distress
(no exposure, prenatal exposure only, concurrent exposure only, both prenatal and
concurrent exposure) and the risk of psychiatric disorder in 12-17-year-olds.

Results:

The odds of major depressive disorder (OR=1.29, 95% CI: 1.01-1.67) and
ADHD (OR=1.30, 95% CI: 1.02-1.65) increased with increasing exposure to
maternal distress. Associations between increasing levels of maternal distress and
several psychiatric disorders were amplified in males.

Conclusions:

The accumulation of exposure to maternal distress over time predicts
offspring psychopathology in adolescence and emphasizes the significance of the
early detection of maternal distress and ongoing monitoring and intervention to
reduce the burden of mental disorders in offspring.
Clanes familiares en España en el contexto del crimen organizado
Authors: Cano-Paños Miguel Ángel
Published: November 2021

Este artículo tiene como objetivo analizar las estrategias que se han desarrollado recientemente en España para combatir las actividades delictivas de los clanes familiares dedicados al crimen organizado, desde un punto de vista policial, penal y procesal. Al mismo tiempo se ponen sobre la mesa una serie de medidas de carácter preventivo dirigidas a impedir el nacimiento y consolidación de estos clanes familiares. La metodología utilizada ha consistido básicamente en la consulta de fuentes abiertas, tanto en trabajos doctrinales publicados como en artículos de prensa referidos al fenómeno de los clanes familiares. También se ha acudido a la información obtenida en una entrevista a un agente de la Policía Nacional española, que permitió obtener información novedosa de primera mano sobre las medidas policiales y penales en este contexto.
El sistema de inteligencia criminal ante las nuevas amenazas y oportunidades del ciberespacio
Authors: Paya-Santos Claudio , Luque-Juárez José María
Published: November 2021

Este trabajo analiza las distintas fases y ciclos de la inteligencia criminal para discernir de qué manera el ciberespacio supone un impacto en ellas, así como establecer si el ciclo clásico de la inteligencia es válido para el trabajo de inteligencia en este dominio. A partir de ello, se evidencia cómo las fases de inteligencia clásica guardan una estrecha relación en su concepto con características transversales que pueden ejecutarse para obtener inteligencia en el ciberespacio, pero cuyos procedimientos provienen de otras épocas en que el ciberespacio no existía como concepto. Se plantean, entonces, las necesidades ante las nuevas amenazas y las inéditas oportunidades que brinda el desarrollo tecnológico del dominio ciberespacial.
Futuros escenarios: análisis prospectivo de la automatización y la crisis medioambiental
Authors: Hernando Cuñado Jorge , Enríquez-Román Javier Antonio
Published: November 2021

El siglo XXI ha traído una crisis dual y contradictoria surgida de la automatización y el deterioro medioambiental, dos factores que dan incertidumbre a esta época histórica. Este artículo aborda algunas de las interacciones entre estas dos dinámicas en el campo de la seguridad mediante técnicas prospectivas. A través del análisis de cuatro informes de distintas organizaciones, se descubren tendencias futuras clave en el área de la seguridad: movimientos migratorios asociados al cambio climático, inestabilidad social provocada por los cambios tecnológicos o la irrupción de pandemias asociadas al deterioro de los ecosistemas. Este análisis prospectivo permite modelar el futuro mediante las acciones presentes, para así romper el aura de inevitabilidad sobre las consecuencias negativas de estos dos factores.
Yoga: A Holistic Approach to Addiction Treatment and Recovery
Authors:   Associate professor in the department to Social Work, East Tennessee State University, Johnson City, Greene Dorothy S
Published: November 2021

Yoga is increasingly becoming a strategy for wellness in the United States. A 2016 survey found that nearly 37 million Americans practice yoga and an additional 12 million say they intend to try it in the coming year. Yoga is also being studied as an intervention for a number of physical and behavioral health disorders. This short report examines yoga’s utility as a treatment or adjunctive tool for addiction recovery. Because addiction is characterized as a biopsychosocial-spiritual disorder and yoga is a holistic practice focusing on the integration of body, mind, and spirit, It is logical to test yoga's efficacy on the treatment and recovery of addiction. Yoga’s positive effect on craving and negative mood states make it a promising modality for addiction recovery.
A 12-Month Follow-Up of the Effects of a Digital Diabetes Prevention Program (VP Transform for Prediabetes) on Weight and Physical Activity Among Adults With Prediabetes: Secondary Analysis
Authors: Batten Ryan , Alwashmi Meshari F , Mugford Gerald , Nuccio Misa , Besner Angele , Gao Zhiwei
Published: November 2021

Background

The prevalence of diabetes is increasing rapidly. Previous research has demonstrated the efficacy of a diabetes prevention program (DPP) in lifestyle modifications that can prevent or delay the onset of type 2 diabetes among individuals at risk. Digital DPPs have the potential to use technology, in conjunction with behavior change science, to prevent prediabetes on a national and global scale.

Objective

The aim of this study is to investigate the effects of a digital DPP (Virgin Pulse [VP] Transform for Prediabetes) on weight and physical activity among participants who had completed 12 months of the program.

Methods

This study was a secondary analysis of retrospective data of adults with prediabetes who were enrolled in VP Transform for Prediabetes for 12 months of the program. The program incorporates interactive mobile computing, remote monitoring, an evidence-based curriculum, behavior tracking tools, health coaching, and online peer support to prevent or delay the onset of type 2 diabetes.

Results

The sample (N=1095) was comprised of people with prediabetes who completed at least 9 months of the VP Transform for Prediabetes program. Participants were 67.7% (n=741) female, with a mean age of 53.6 (SD 9.75) years. After 12 months, participants decreased their weight by an average of 10.9 lbs (5.5%; P<.001) and increased their physical activity by 91.2 (P<.001) minutes.

Conclusions

These results suggest that VP Transform for Prediabetes is effective at preventing type 2 diabetes through a significant reduction in body weight and increase of physical activity. Furthermore, these results suggest that the DPP remains effective 12 months after beginning the program. A prospective randomized controlled clinical study is warranted to validate these findings.
Perceived Impact of Outdoor Swimming on Health: Web-Based Survey
Authors: Massey Heather , Gorczynski Paul , Harper C Mark , Sansom Lisa , McEwan Kieren , Yankouskaya Alla , Denton Hannah
Published: November 2021

Background

Outdoor swimming in lakes, lidos (outdoor pools), rivers, and the sea has grown in popularity in many countries, including the United Kingdom. Many anecdotal accounts indicate improvements in medical conditions, which are considered a consequence of outdoor swimming.

Objective

The aim of this study is to better understand outdoor swimmers’ perceptions of their health and the extent to which participation impacted their existing self-reported symptoms.

Methods

A survey was conducted to investigate outdoor swimming behaviors and reports of any diagnosed medical conditions. Medical conditions were coded into categories, and descriptive statistics were generated regarding the outdoor swimmers’ behaviors and the effect that outdoor swimming had on their medical symptoms if any. The medical categories were clustered into five larger categories based on their prevalence in the current sample: mental health; musculoskeletal and injury; neurological; cardiovascular and blood disease; and other, which comprises inflammatory, immune, endocrine, and respiratory conditions.

Results

In total, 722 outdoor swimmers responded, of whom 498 (68.9%) were female. The probability of outdoor swimming having some positive impact on health across all medical categories was 3.57 times higher compared with no impact (B=1.28, 95% CI 0.63-1.91; P<.001), 44.32 times higher for the mental health category (B=3.79, 95% CI 2.28-5.30; P<.001), 5.25 times higher for musculoskeletal and injury category (B=1.66, 95% CI 0.52-2.79; P=.004), and 4.02 times higher for the other category (B=1.39, 95% CI 0.27-2.51; P=.02). Overall, outdoor swimming was associated with perceived reductions in symptoms of poor mental health (χ22=25.1; P<.001), musculoskeletal and injury (χ22=8.2; P=.04), cardiovascular and blood (χ22=14.7; P=.006), and other conditions (χ22=18.2; P<.001).

Conclusions

Physical activity in the form of outdoor swimming is perceived to have positive impacts on health and is associated with perceived symptom reductions in mental health, musculoskeletal and injury, and cardiovascular and blood conditions. This study cannot provide causal relationships or provide mechanistic insights. However, it does provide a starting point for more targeted prospective intervention research into individual conditions or categories of conditions to establish the impact in those who choose to start outdoor swimming.
The Contact Dermatitis Quality of Life Index (CDQL): Survey Development and Content Validity Assessment
Authors: Hill Mary K , Laughter Melissa R , Harmange Cecile I , Dellavalle Robert P , Rundle Chandler W , Dunnick Cory A
Published: November 2021

Background

There is limited measurement and reporting of quality of life (QoL) outcomes for patients with contact dermatitis (CD).

Objective

The purpose of this study is to develop a standardized Contact Dermatitis Quality of Life index (CDQL) for adult patients.

Methods

A list of 81 topics was compiled from a review of QoL measures used previously in CD research. A total of 2 rounds of web-based Delphi surveys were sent to physicians who registered to attend the 2018 American Contact Dermatitis Society meeting, asking that they rank the relevance of topics for measuring QoL in CD using a 4-point scale. Items met consensus for inclusion if at least 78% of respondents ranked them as relevant or very relevant, and their median score was ≥3.25.

Results

Of the 210 physicians contacted, 34 physicians completed the initial survey and 17 completed the follow-up survey. A total of 22 topics met consensus for inclusion in the CDQL, addressing symptoms, emotions, functions of daily living, social and physical functions, work/school functions, and treatment.

Conclusions

This study was limited by the following factors: few open-ended questions in the initial survey, a lack of direct patient feedback, and long survey length, which likely contributed to lower survey participation. The CDQL is a comprehensive, CD-specific QoL measure developed on the basis of expert consensus via a modified Delphi process to be used by physicians and other health care professionals who care for adult patients with contact dermatitis.
How Clinicians Perceive Artificial Intelligence–Assisted Technologies in Diagnostic Decision Making: Mixed Methods Approach
Authors: Hah Hyeyoung , Goldin Deana Shevit
Published: November 2021

Background

With the rapid development of artificial intelligence (AI) and related technologies, AI algorithms are being embedded into various health information technologies that assist clinicians in clinical decision making.

Objective

This study aimed to explore how clinicians perceive AI assistance in diagnostic decision making and suggest the paths forward for AI-human teaming for clinical decision making in health care.

Methods

This study used a mixed methods approach, utilizing hierarchical linear modeling and sentiment analysis through natural language understanding techniques.

Results

A total of 114 clinicians participated in online simulation surveys in 2020 and 2021. These clinicians studied family medicine and used AI algorithms to aid in patient diagnosis. Their overall sentiment toward AI-assisted diagnosis was positive and comparable with diagnoses made without the assistance of AI. However, AI-guided decision making was not congruent with the way clinicians typically made decisions in diagnosing illnesses. In a quantitative survey, clinicians reported perceiving current AI assistance as not likely to enhance diagnostic capability and negatively influenced their overall performance (β=–0.421, P=.02). Instead, clinicians’ diagnostic capabilities tended to be associated with well-known parameters, such as education, age, and daily habit of technology use on social media platforms.

Conclusions

This study elucidated clinicians’ current perceptions and sentiments toward AI-enabled diagnosis. Although the sentiment was positive, the current form of AI assistance may not be linked with efficient decision making, as AI algorithms are not well aligned with subjective human reasoning in clinical diagnosis. Developers and policy makers in health could gather behavioral data from clinicians in various disciplines to help align AI algorithms with the unique subjective patterns of reasoning that humans employ in clinical diagnosis.
A Two-Minute Walking Test With a Smartphone App for Persons With Multiple Sclerosis: Validation Study (Preprint)
Authors: van Oirschot Pim , Heerings Marco , Wendrich Karine , den Teuling Bram , Dorssers Frank , van Ee René , Martens Marijn Bart , Jongen Peter Joseph
Published: November 2021

BACKGROUND

Walking disturbances are a common dysfunction in persons with multiple sclerosis (MS). The 2-Minute Walking Test (2MWT) is widely used to quantify walking speed. We implemented a smartphone-based 2MWT (s2MWT) in MS sherpa, an app for persons with MS. When performing the s2MWT, users of the app are instructed to walk as fast as safely possible for 2 minutes in the open air, while the app records their movement and calculates the distance walked.

OBJECTIVE

The aim of this study is to investigate the concurrent validity and test-retest reliability of the MS sherpa s2MWT.

METHODS

We performed a validation study on 25 persons with relapsing-remitting MS and 79 healthy control (HC) participants. In the HC group, 21 participants were matched to the persons with MS based on age, gender, and education and these followed the same assessment schedule as the persons with MS (the HC-matched group), whereas 58 participants had a less intense assessment schedule to determine reference values (the HC-normative group). Intraclass correlation coefficients (ICCs) were determined between the distance measured by the s2MWT and the distance measured using distance markers on the pavement during these s2MWT assessments. ICCs were also determined for test-retest reliability and derived from 10 smartphone tests per study participant, with 3 days in between each test. We interviewed 7 study participants with MS regarding their experiences with the s2MWT.

RESULTS

In total, 755 s2MWTs were completed. The adherence rate for the persons with MS and the participants in the HC-matched group was 92.4% (425/460). The calculated distance walked on the s2MWT was, on average, 8.43 m or 5% (SD 18.9 m or 11%) higher than the distance measured using distance markers (n=43). An ICC of 0.817 was found for the concurrent validity of the s2MWT in the combined analysis of persons with MS and HC participants. Average ICCs of 9 test-retest reliability analyses of the s2MWT for persons with MS and the participants in the HC-matched group were 0.648 (SD 0.150) and 0.600 (SD 0.090), respectively, whereas the average ICC of 2 test-retest reliability analyses of the s2MWT for the participants in the HC-normative group was 0.700 (SD 0.029). The interviewed study participants found the s2MWT easy to perform, but they also expressed that the test results can be confronting and that a pressure to reach a certain distance can be experienced.

CONCLUSIONS

The high correlation between s2MWT distance and the conventional 2MWT distance indicates a good concurrent validity. Similarly, high correlations underpin a good test-retest reliability of the s2MWT. We conclude that the s2MWT can be used to measure the distance that the persons with MS walk in 2 minutes outdoors near their home, from which both clinical studies and clinical practice can benefit.
Identification of the Most Suitable App to Support the Self-Management of Hypertension: Systematic Selection Approach and Qualitative Study (Preprint)
Authors: Alessa Tourkiah , Hawley Mark , de Witte Luc
Published: November 2021

BACKGROUND

Smartphone apps are increasingly being used to aid in hypertension self-management, and a large and ever-growing number of self-management apps have been commercially released. However, very few of these are potentially effective and secure, and researchers have yet to establish the suitability of specific hypertension apps to particular contexts.

OBJECTIVE

The aim of this study is to identify the most suitable hypertension app in the context of Saudi Arabia and its health system.

METHODS

This study used a 2-stage approach to selecting the most suitable app for hypertension self-management. First, a systematic selection approach was followed to identify a shortlist of the most suitable apps according to the criteria of potential effectiveness, theoretical underpinning, and privacy and security. Second, an exploratory qualitative study was conducted to select the most suitable from the shortlist: 12 doctors were interviewed, and 22 patients participated in 4 focus groups. These explored participants’ attitudes towards self-management apps in general, and their views towards the apps identified via the systematic selection process. The qualitative data were analyzed using framework analysis.

RESULTS

In the first stage, only 5 apps were found to be potentially effective while also having a theoretical underpinning and protecting users’ data. In the second stage, both doctors and patients were generally interested in using hypertension apps, but most had no experience with these apps due to a lack of awareness of their availability and suitability. Patients and doctors liked apps that combine intuitive interfaces with a pleasant and clear visual design, in-depth features (eg, color-coded feedback accompanied with textual explanations), activity-specific reminders, and educational content regarding hypertension and potential complications. When the pros and cons of the 5 apps were discussed, 3 apps were identified as being more suitable, with Cora Health rated the highest by the participants.

CONCLUSIONS

Only 5 apps were deemed potentially effective and secure. Patients’ and doctors’ discussions of the pros and cons of these 5 apps revealed that 3 out of the 5 are clearly more suitable, with the Cora Health app being judged most suitable overall.
Co-Development of Implementation Interventions to Support Parent-Led Infant Pain Care: A Collaborative, Theoretically Informed Study (Preprint)
Authors: University) Britney , Cassidy Christine , van Wijlen Jacqueline , Correll Quinn , Campbell-Yeo Marsha , Hendra Sionnach , Martin-Misener Ruth , Leuschner Jennifer , Cameron Ashley
Published: November 2021

BACKGROUND

Untreated infant pain is associated with adverse health outcomes. Despite the strong evidence for accessible, effective, and low-cost parent-led pain-relieving interventions such as breast/chestfeeding and skin-to-skin contact, these interventions are not routinely used.

OBJECTIVE

The objective of this research is to support implementation of parent-led pain interventions by 1) identifying barriers and facilitators to parent-led, evidence-informed infant pain care during acute procedures, and 2) developing theory-informed, contextually relevant implementation interventions for supporting the use of parent-led infant pain care in hospital and community contexts.

METHODS

This study will consist of two phases that follow a systematic, theoretically informed approach guided by the Theoretical Domains Framework (TDF) and the Behaviour Change Wheel (BCW). In Phase 1, we will utilize a qualitative descriptive design to explore barriers and facilitators to use of parent-led infant pain care from the perspectives of hospital and community-based clinicians, clinical leaders, and families. In Phase 2, we will utilize the BCW to design tailored implementation interventions that have evidence for effectively addressing identified barriers in collaboration with an advisory committee of administrative, clinical, and family leaders.

RESULTS

Following completion of this study we will have co-designed, theoretically informed implementation interventions that can be pilot tested and experimentally applied.

CONCLUSIONS

Findings will be used to implement parent-led interventions that improve patient safety and health outcomes for diverse families.
Patterns of Promotional Content by Dermatology Influencers on TikTok (Preprint)
Authors: Ranpariya Varun K , Fathy Ramie , Chu Brian , Wang Sonia , Lipoff Jules B
Published: November 2021

UNSTRUCTURED

N/a
Feasibility, Acceptability, and Preliminary Efficacy of an App-Based Meditation Intervention to Decrease Firefighter Psychological Distress and Burnout: A One-Group Pilot Study (Preprint)
Authors: Pace Thaddeus W W , Zeiders Katharine H , Cook Stephanie H , Sarsar Evelyn D , Hoyt Lindsay T , Mirin Nicholas L , Wood Erica P , Tatar Raquel , Davidson Richard J
Published: November 2021

BACKGROUND

Firefighters are often exposed to occupational stressors that can result in psychological distress (ie, anxiety and depression) and burnout. These occupational stressors have only intensified with the onset of the COVID-19 pandemic and will likely persist in the postpandemic world.

OBJECTIVE

To address occupational stressors confronting firefighters, we pilot tested a novel, cost-effective, smartphone app–based meditation intervention created by Healthy Minds Innovations that focused on mindfulness (awareness) training along with practices designed to cultivate positive relationships (connection), insight into the nature of the self (insight), and a sense of purpose in the context of challenge (purpose) with a sample of professional firefighters from a large metropolitan area in southwestern United States.

METHODS

A total of 35 participants were recruited from a closed online group listserv and completed the self-guided 10-unit meditation app over the course of 10 days, at 1 unit per day. We assessed anxiety symptoms, depression symptoms, burnout, and negative affect as well as saliva diurnal cortisol rhythm, an objective indicator of stress-related biology, before and after use of the meditation app.

RESULTS

This study demonstrated the meditation app was both feasible and acceptable for use by the majority of firefighters. We also found significant reductions in firefighters’ anxiety (P=.01), burnout (P=.05), and negative affect (P=.04), as well as changes in cortisol diurnal rhythm, such as waking cortisol (P=.02), from before to after use of the meditation app.

CONCLUSIONS

Our study findings call for future research to demonstrate the efficacy of this meditation app to reduce psychological distress and burnout in firefighters.
SYNERGISTIC IMMUNOMODULATORY ACTIVITY OF AQUEOUS ROOT EXTRACT OF ASPARAGUS RACEMOSUS WILLD AND ETHANOL WHOLE PLANT EXTRACT OF BOERHAVIA DIFFUSA LINN
Authors: KUMARI AMRITA , CHAKRABORTY MAINAK , SARKAR NILANJAN , BOSE SEKHAR KUMAR , ROY KALYAN , KARUNAKARAN GAUTHAMAN
Published: November 2021

Objective: On the basis of traditional use and Ethno pharmacological evidences Boerhavia diffusa whole plant and root part of Asparagus racemosus (Shatavari) both are widely used to enhance the immunity. But in combination there is no scientific evidence so current study was designed.
Methods: Laboratory based study, namely, carbon clearance, cyclophosphamide induced immune suppression and neutrophil adhesion was designed using mice as an experimental animals in different combination of aqueous whole plant extract of B. diffusa and methanol extract of root part of A. racemosus were used as a test drug in the ratio 1:1, 1:2, and 2:1 (100 mg/kg) against the established standard drug Ashwagandha.
Results: The results revealed that animals treated with combined extract (1:1, 1:2, and 2:1) at a dose of 100 mg/kg increase rate of carbon clearance from blood, there is significance alternation in blood parameter in cyclophosphamide group and also improve the Neutrophil adhesion when treated with different combination of polyherbal formulation treated groups.
Conclusion: The polyherbal formulation in different ratio showing good significant immunomodulatory activity as compare to standard.
IMPACT OF FAMILY STIGMA AND CAREGIVER BURDEN ON QUALITY OF LIFE AMONG WIVES OF PATIENTS WITH ALCOHOL AND OPIOID USE DISORDER
Authors: GARG ROHIT , GUPTA ABHISHEK , KUNDAL DEEPAM , SINGH SAVIJOT
Published: November 2021

Objectives: Spouses of patients with alcohol use disorder (AUD) and opioid use disorder (OUD) suffer from burden, stigma, and low quality of life (QoL). The present study assessed the impact of stigma and burden on QoL among wives of patients with AUD and OUD.
Methods: 90 wives of in-patients with severe AUD (n=54) and OUD (n=36) as per DSM-5 were assessed using socio-demographic pro forma, WHO QoL Bref Hindi, Hindi family stigma scale and Family Burden Interview Schedule. Statistical Package for the Social Sciences Inc., Chicago, IL, version 25.0 for Windows was used for analysis. Appropriate statistical tests including Kolmogorov–Smirnov tests of normality, Mann–Whitney test, and Kruskal–Wallis test were used. To see the relationship between two variables Pearson Correlation coefficient was calculated. All statistical tests were two-sided and performed at a significance level of α=.05.
Results: Majority of the wives were more than 30 years old, literate and belonged to rural areas. Higher financial burden reduced overall QoL (p=0.001**), satisfaction with physical health (0.006**), psychological health (p=0.032*), and environment (p=0.001**). There was a negative correlation of satisfaction with environment with disruption of family interaction (p=0.003**), burden on mental health (p=0.001**), overall burden (p=0.000**), and discrimination (p=0.032*).
Conclusion: QoL of spouses of patients with AUD and OUD reduces significantly due to stigma and burden. Enhancing QoL of spouses should be a part of management of AUD and OUD.
ОПТИМИЗАЦИЯ ЗАПОМИНАЮЩИХ СВОЙСТВ ОТ СОСТАВА МЕМРИСТОРА НА ОСНОВЕ SIOX, ПОЛУЧЕННОГО ПЛАЗМОХИМИЧЕСКИМ ОСАЖДЕНИЕМ
Authors: Гисматулин А.А. , Гриценко В.А. , Камаев Г.Н.
Published: November 2021

Исследованы запоминающие свойства мемристоров на основе SiOx, полученных плазмохимическим осаждением. Установлено, что пленки SiOx нестехиометрического состава проявляют резистивные переключения при х = 0,7-1,8. Оптимальными запоминающими свойствами обладает мемристор на основе SiOL1.
КОНСТРУКТИВНО-ТЕХНОЛОГИЧЕСКИЕ ОСОБЕННОСТИ ПРОЕКТИРОВАНИЯ АНАЛОГОЦИФРОВЫХ СХЕМ С ПРОЕКТНЫМИ НОРМАМИ 28 НМ
Authors: Горшкова Н.М.
Published: November 2021

Рассмотрены конструктивно-технологические особенности проектирования аналого-цифровых схем, выполненных по КМОП-технологии 28 нм, повышающие выход годных. Предложен метод, повышающий согласование активных и пассивных приборов. Приведены конструктивные решения для предотвращения тиристорного эффекта в потенциально опасных местах.
Encoding-dependent generalization bounds for parametrized quantum circuits
Authors: Caro Matthias C. , Gil-Fuster Elies , Meyer Johannes Jakob , Eisert Jens , Sweke Ryan
Published: November 2021

A large body of recent work has begun to explore the potential of parametrized quantum circuits (PQCs) as machine learning models, within the framework of hybrid quantum-classical optimization. In particular, theoretical guarantees on the out-of-sample performance of such models, in terms of generalization bounds, have emerged. However, none of these generalization bounds depend explicitly on how the classical input data is encoded into the PQC. We derive generalization bounds for PQC-based models that depend explicitly on the strategy used for data-encoding. These imply bounds on the performance of trained PQC-based models on unseen data. Moreover, our results facilitate the selection of optimal data-encoding strategies via structural risk minimization, a mathematically rigorous framework for model selection. We obtain our generalization bounds by bounding the complexity of PQC-based models as measured by the Rademacher complexity and the metric entropy, two complexity measures from statistical learning theory. To achieve this, we rely on a representation of PQC-based models via trigonometric functions. Our generalization bounds emphasize the importance of well-considered data-encoding strategies for PQC-based models.
The contribution of organized food retail to the Greek socio-economic development during the years of economic crisis
Authors: Zisoudis Nikolaos , Zafeiriou Eleni , Garefalakis Alexandros , Spinthiropoulos Konstantinos , Garefalakis Stavros
Published: November 2021

The economic crisis in the EU had severe impacts not only on the performance of the domestic economy but also on the living standard for the citizens. The extended spread of this crisis resulted in limitation in the disposable income and significant negative changes have taken place with negative consequences for the corporate economic performance and competitiveness (de Jorge Moreno, Castillo, & de Zuani Masere, 2010). Within the dominance of certain conditions of economic crisis, there are a few firms that act as lighting exceptions. The present work makes an effort, to unveil the role of selected supermarket retail chain stores in the performance of certain macroeconomic parameters and therefore to illustrate the mechanism through which the restoration of the economy in Greece becomes feasible. More specifically, based on data derived by Eurostat and Greek National Statistics with the assistance of the findings of present analysis that validate a significant contribution of the firms studied to macroeconomic parameters such as national income or employment it may provide policymakers with knowledge tools to promote corporate efforts of this type and in sequence to lead the macroeconomic system in a trajectory of economic growth.
Metagenomic targets of balancing selection in the human gut
Authors: Moeller Andrew H.
Published: November 2021

Bacteria in the human gut contend with numerous fluctuating
environmental variables, including bouts of extreme selective agents
like antibiotics. Theory predicts that oscillations in the adaptive
landscape can impose balancing selection on bacterial populations,
leaving characteristic signatures in the sequence variation of
functionally significant genomic loci. Despite their potential
importance for gut bacterial adaptation, the metagenomic targets of
balancing selection have not been identified. Here, I present population
genetic evidence that balancing selection maintains allelic diversity in
multidrug efflux pumps of multiple predominant bacterial species in the
human gut metagenome. Metagenome wide scans of 566,958 core open reading
frames (CORFs) from 287 bacterial species represented by 118,617
metagenome assembled genomes (MAGs) indicated that most CORFs have been
conserved by purifying selection. However, dozens of CORFs displayed
positive Tajima’s D values that deviated significantly from their
species’ genomic backgrounds, indicating the action of balancing
selection. The AcrB subunit of a multidrug efflux pump (MEP) in
Bacteroides dorei displayed the highest Tajima’s D of any CORF, and AcrB
and other MEPs from a diversity of bacterial species were significantly
enriched among the CORFs with the highest Tajima’s D values. Crystal
structures indicated that the regions under balancing selection bind
tetracycline and macrolide antibiotics. Other proteins identified as
targets of balancing selection included synthases, hydrolases, and ion
transporters. Intriguingly, bacterial species experiencing balancing
selection were the most abundant in the human gut based on metagenomic
data, further suggesting fitness benefits of the allelic variation
identified.
Successful use of veno-venous extracorporeal membrane oxygenation for acute chest syndrome in a child with sickle cell disease and SARS-CoV-2
Authors: Koh Wonshill , Malik Punam , Whitehead Jason , Morales David , Hayes Don
Published: November 2021

Children with sickle cell disease (SCD) are at increased risk for severe
illness due to severe acute respiratory syndrome Coronavirus 2
(SARS-CoV-2). We describe the successful native lung recovery of a child
with SCD referred for lung transplant (LTx) evaluation who was on
prolonged veno-venous extracorporeal membrane oxygenation (VV-ECMO). He
initially presented with acute chest syndrome complicated by SARS-CoV-2
infection that ultimately required dual-lumen, single bicaval VV-ECMO
cannulation for respiratory support. Despite increased risk of hemolysis
and thrombosis from SCD and SARS-CoV-2 infection, he was successfully
supported on VV-ECMO for 71 days without complications leading to native
lung recovery with meticulous management of his SCD therapy. This report
provides new insight on our approach to VV-ECMO support in a child with
SCD and SARS-CoV-2 infection. With a successful outcome, the patient has
returned home but still on mechanical ventilation with LTx still an
option if he is not eventually liberated from invasive respiratory
support.
Representation of slim lattice by poset
Authors: Gorjanac-Ranitovic Marijana , Tepavcevic Andreja
Published: November 2021

In this paper, we present the necessary and sufficient conditions for a poset
to be a poset of the union of join and meet irreducible elements of the slim
lattice. Slim lattices are special finite lattices that are intensively
investigated recently. The problem that we solved in this paper is a
generalization of the problem proposed very recently by Cz?dli.
Association between blood pressure and the risk of chronic kidney disease in treatment-naïve hypertensive patients
Authors: Lee Haekyung , Kwon Soon Hyo , Jeon Jin Seok , Noh Hyunjin , Han Dong Cheol , Kim Hyoungnae
Published: November 2021

Background: Although hypertension is a well-known risk factor for chronic kidney disease (CKD), the blood pressure (BP) at which antihypertensive interventions should be initiated remains to be determined. Therefore, we investigated the association between BP and CKD in treatment-naïve individuals.Methods: This prospective cohort study considered 7,343 individuals in the Korean Genome and Epidemiology Study who were not taking antihypertensive medications. Subjects were categorized into six groups according to their systolic BP (SBP) and five groups according to their diastolic BP (DBP). The primary outcome was incident CKD, which was defined as an estimated glomerular filtration rate of <60 mL/min/1.73 m2 or the development of proteinuria. The secondary outcome was incident cardiovascular disease (CVD).Results: In the time-varying Cox models, the hazard ratios (95% confidence interval [CI]) for CKD were 1.39 (1.10–1.77) with SBP 130–139 mmHg, 1.79 (1.40–2.28) with SBP 140–159 mmHg, and 3.22 (2.35–4.40) with SBP ≥ 160 mmHg, compared with SBP 100–119 mmHg. In addition, the hazard ratios (95% CI) for CKD were 1.88 (1.48–2.37) with DBP 90–99 mmHg and 4.30 (3.20–5.76) with DBP ≥ 100 mmHg, compared with DBP 70–79 mmHg. A significantly increased CVD risk was also observed in subjects with SBP ≥ 130 mmHg or DBP ≥ 90 mmHg.Conclusion: Our findings indicate that SBP ≥ 130 mmHg and DBP ≥ 90 mmHg are associated with an increased risk of CKD. Therefore, BP-lowering strategies should be considered starting at those thresholds to prevent CKD development.
Build Awareness Of The Hamlet Of Both Rajumas About The Cleanliness Of The Health & The Environment Community
Authors: Suryansah Suryansah - , Hariadi Hariadi , Nopiana Rina
Published: November 2021

Pengabdian masyarakat ini telah dilaksanakan pada bulan Juli hingga Agustus 2020 di Dusun Rajumas Desa Mantang Kecamatan Batukliang. Pengabdian ini bertujuan untuk membangun, menumbuhkan dan meningkatkan kepedulian masyarakat khususnya dusun rajumas terhadap kebersihan dan kesehatan lingkungan dikarnakan lingkungan atau dusun rajumas akan menjadi wisata desa dan wisata kebersihan dan kesehatan. Pengabdian ini dilakukan dalam bentuk observasi, tindakan dan penyuluhan tentang pentingnya kebersihan dan kesehatan lingkungan itu sendiri, serta aksi lapangan dalam bentuk kerja bakti yang melibatkan para remaja atau pemuda rajumas yang membentuk organisasi namanya pemuda garuda emas ikut serta dan berperan aktif untuk meningkatkan kebersihan dan kesehatan lingkungan. Setelah pengabdian selesai, tingkat kepedulian sebagian masyarakat terhadap kebersihan dan kesehatan lingkungan mulai meningkat. Hal ini dapat dilihat dari peningkatan peran aktif dan antusiasme mereka dalam mengikuti kegiatan aksi lapangan dalam meningkatkan kebersihan dan kesehatan lingkungan.
Socialization of Cricket to Physical Education Students University of Bengkulu
Authors: Nopiyanto Yahya Eko , Defliyanto Defliyanto , Raibowo Septian , Ilahi Bogy Restu
Published: November 2021

The purpose of the socialization of cricket was increased the knowledge of physical education students about the development of cricket in Indonesia and improved the skills of physical education students in playing cricket. The socialization activity was carried out in the physical education study program, University of Bengkulu. Partners in this activity were second semester physical education students, totaling 35 students. This activity was carried out on March 14-15 2020. The forms of activities carried out were socialization and practicum. This activity was carried out with a model of small group discussion, lectures and demonstrations. The stages carried out in this activity consist of three stages, namely: socialization, practicum, and evaluation. Based on the results of the activities and the results of the evaluation, it can be concluded that the socialization of cricket to physical education students increased knowledge about cricket and skills in playing cricket.
Socialization Training Programs Physical Condition Of The Athletes In The Face Of The Situation Of The Pandemic And Post Pandemic In KONI Kota Payakumbuh Sumatera Barat
Authors: Yendrizal Yendrizal , Yenes Ronni , N Erizal
Published: November 2021

Based on studies in the field, found the problem that almost all of the coaches of the sport in the KONI Kota Payakumbuh have constraints in the preparation of training programs physical condition to the athlete in a situation of pandemic COVID-19 right now. It is originated from the low understanding of the trainers about the basic concepts of the physical conditions in sports coaching achievement for athletes. Through this community service activity of the team of community services Universitas Negeri Padang will give you a full u in scientific to the participants about: (a) the basic concept of training the physical conditions in sports coaching achievements against the athlete. (b) basic Concepts related to test and measurement of the physical condition of the athlete. (c) the Design and preparation of training programs physical conditions in the face of the situation of the pandemic and post-pandemic which according to The rules of the science of Sports Coaching (d) Innovation forms of exercise physical conditions with the intensity adjusted to each branch of the sport. The delivery of material to the participants was performed through the stages of presentation, discussion, practice with mentoring, and evaluation. The results of the activities of the participants obtained is: (a) Have an understanding of the basic concepts of training the physical conditions in sports coaching achievements. (b) Have an understanding and be able to perform the test, measurement, and evaluation of the physical condition of the athlete. (c) is Capable of designing training programs physical conditions in the face of the situation of the pandemic and post-pandemic. (d) able to innovate in compiling forms of exercise physical conditions with the intensity adjusted to each branch of the sport.
Nutritional Status For Increasing Performance
Authors: Pitriani Pipit , Basiran Basiran , Hidayah Nida'ul
Published: November 2021

Nutritional status in athletes is one of the important factors that affect athlete performance. Athlete's knowledge of nutrition is still lacking. Malnutrition and other health problems are found many in athletes. The purpose of this activity is trained athletes to improve the understanding of nutritional status and measure anthropometry to improve performance. This training contains materials that is needed to improve athlete's knowledge on nutritional status and anthropometric measurements. Further it can be used in the training process or in match conditions. This community service activity was attended by 29 participants consisting of female and male athletes as well as handball trainers. The activity is carried out online. Before and after the training participants fill out a google form for data on body weight, height, and questions about training materials. From the results of data processing, the average height for male athletes was 176 ± 6.33cm and for female athletes 164 ± 5.79cm. Meanwhile, the body weight of female athletes is 60.5 ± 8.3kg and male athletes are 74.02 ± 9.05kg. BMI in female athletes is 22.5 ± 2.2kg / m2 and in male athletes 23.88 ± 1.88 kg / m2. The mean pre-test score for female athletes was 60.35 ± 11.09, while for male athletes it was 60.35 ± 14.69. The average post-test score for female athletes was 67.85 ± 11.90, while for male athletes the average post-test score was 72.5 ± 9.20. Thus, the difference (gain) change in post-test scores to pre-test in female athletes is 12.43% and 20.12% in men. From this training, it can be concluded that there is an increase in the knowledge of handball athletes regarding nutritional status, nutrition, and dietary regulation in athletes. It is hoped that further this community service activity can be carried out in terms of determining the calorie and nutritional needs of athletes as well as athletes can be given knowledge about how to make food menus according to the needs of athletes.
Implementation of Integrated Shuttle Time in Involving and Developing Badminton Sports
Authors: Donie Donie , Arifianto Irfan , Hermanzoni Hermanzoni
Published: November 2021

Badminton sport coaching which tends to be instant causes a gap between athletes' achievements in Sijunjung Regency and sports activities for potential athletes of elementary school age. It takes a program that can socialize badminton among elementary school students that is able to foster interest and motivation to play badminton and form a coaching forum into the badminton coaching club. The integrated Shuttle Time program is an effort to socialize and increase interest in playing badminton in elementary school students in general in Sijunjung Regency. The partner in this activity is the Sijunjung Regency Sports Facilities Association (ISORI). The key to implementing badminton with Shuttle Time is to provide badminton lessons that are cheaper, more interesting, fun and safe for elementary school students. The method used in this activity is through several stages, namely the first stage of direct field observation and coordination with related parties in this activity. The second stage provides Shuttle Time training for elementary school sports teachers and the third stage the teacher implements the shuttle time for students. The result of this activity is that the training activities will be carried out for 3 days and the teacher will get provisions in implementing this shuttle time in learning badminton in class hours and extracurricular development activities
Evaluasi Pembelajaran Daring Melaui Media E-Learning di Masa Pandemi Covid-19 pada Mata Kuliah Fisiologi Olahraga
Authors: Sepriani Rika , Ambiyar Ambiyar , Aziz Ishak
Published: November 2021

The problem in this study is that there has not been an evaluation of online learning through e learning during the Covid-19 pandemic in the Sports Physiology course. For this reason, this study aims to determine the achievement of online learning that has been carried out until mid-semester as a form of learning evaluation. In this study, the sample was obtained from students who took the Sports Physiology lecture who met the inclusion criteria as many as 58 people. This type of research is a quantitative descriptive study using two methods, survey methods namely in the form of a questionnaire to determine the ability of students to access e learning and an essay test to determine student learning outcomes until mid-semester, especially in the cognitive aspects. The results showed that students had been able to access e learning well and had a good average value of learning outcomes.
Studi Eksperimen Pada Unit Kegiatan Mahasiswa Petanque Universitas Islam Riau: Meningkatkan Kesegaran Jasmani Melalui Permainan Hadang dan Bentengan
Authors: Apriani Leni , Sari Merlina , Alpen Joni
Published: November 2021

The purpose of this study was to determine and test the increase in physical fitness through bentengan and obstacle course games. In this study the authors used an experimental method. From the results of paired samples test, it can be seen that the significance value is 0.038, which is smaller than α = 0.05. These results prove that using the game hadang has a significant effect on increasing the level of physical fitness of UIR Petanque UKM athletes. A different thing happened to the fortress game that it was not significantly proven to the level of physical fitness of the Petanque UIR UKM athletes with a value of 0.603. If seen in table 1 the mean value of the game hadang was 1.12, while the game of bentengan was -62, this could mean that the game hadang better than the clash of arms.
Pengaruh Metode Latihan dan Motivasi Berprestasi Terhadap Kemampuan Lay Up Shoot Permainan Bola Basket Ekstakulikuler Siswa SMP N 1 Watampone
Authors: Harliawan Muhammad , Dos Santos Maria Herlinda , Okilanda Ardo
Published: November 2021

The purpose of this study is to determine the effect of the methods section training  and methods overall training motivation achievement shoot lay-up skills in the game of basketball The research is conducted at extracurricular student SMP 4 Watampone ,This study is using  treatment by level 2 x 2. The samples are consisted of 40 student. The technique of data analysis is two ways analysis of variance (ANAVA) and followed by Tuckey's test for significance level of α = 0, 05. The results of this study show that (1) score for method training section (A1) is higher than the method of overall training (A2) at extracurricular student SMPN 1 Watampone ; (2) there is an interaction between practice methods (A) and training motivation (B) shoot lay-up skills in the game of basketball; (3) score of high method section training  (A1B1) is higher than score of high method overall training (A2B1); 4) score of low method section training (A1B2) is lower than score of low method overall training (A2B1)