bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Multiple Degrees-of-Freedom Compliant Parallel Mechanisms Using Improved Beam-Based Structural Optimization Method
Authors: Nguyen Van Tu , Nguyen Minh Tuan , Pham Minh Tuan
Published: June 2022

This paper presents the development of a three degrees-of-freedom (DOF) compliant parallel mechanism (CPM) with spatial motions, i.e., two rotations about the X and Y axes and one translation along the Z axis (θX-θY-Z). Such CPM is synthesized by the improved beam-based structural optimization method. The obtained results suggest that the proposed CPM is able to produce totally decoupled motions illustrated by a diagonal stiffness/compliance matrix, a large workspace of ±22,5 degrees × ±22,5 degrees × ±9,6 mm, fast dynamic response with the first natural frequency of ~100 Hz and high stiffness ratios between actuating and non-actuating directions (with stiffness ratios of 6210 and 2706 for translations and rotations respectively). Finite element analysis (FEA) is employed to evaluate the actual performance of the synthesized CPM with Ti6Al4V material in order to verify the correctness of the synthesis method. The effectiveness of the improved beam-based structural method is demonstrated by the good agreement between the simulation and predicted data with the highest deviations are 8.8% and 6.7% for the stiffness and dynamic properties respectively. In addition, some comparisons are carried out to investigate the advantages as well as disadvantages of the proposed CPM and existing designs. The comparison results show that the 3-DOF CPM presented in this paper has many merits compared to its counterparts. It can be used in various applications, e.g., the micro/nano positioners and alignment systems in precision engineering field due to its good mechanical properties (high stiffness ratios and fast dynamic behavior), large work range and fully-decoupled motion characteristic.
Tool Wear of Cubic Boron Nitride in Intermittent Cutting of Hardened Steel ASTM D2 with High-Pressure Coolant Supply
Authors: Wada Tadahiro
Published: June 2022

To clarify the effect of using high-pressure coolant supply in combination with the intermittent cutting of hardened steel ASTM D2, intermittent cutting of hardened steel was performed with various sintered cubic boron nitride compact (cBN) tools. The result revealed that it was effective to use a high-pressure coolant supply method in combination for intermittent cutting of hardened steel. An effective tool material had a bonding phase of WC-Co-Al and a high content of cBN particles. Furthermore, the more suitable cutting edge shape was "a negative-land width of 0.13mm, a negative-land angle of 45°, and R honing of 0.04 mm".
Capacity Planning Considering Uncertainty Factors
Authors: Phan Mai Ha , Nguyen Tai Duc
Published: June 2022

Capacity planning is the process of determining the production capacity needed by an organization to meet changing demands for its products. Production capacity planning is generally based on all capabilities determining that wireless production is stable, with no fluctuations in machine downtime, variable processing times, defective products, etc., and use the mean for cycle time. However, actual production not only has many fluctuations in human resources that affecting the production time on each stage, but also affected by defective products leading to inaccurate planning. Therefore, planning production capacity under uncertain conditions is essential for any manufacturing enterprise. This paper proposes a model of capacity planning in uncertain conditions using real-time observation and then distributing observation time from which to analyze production capacity. Uncertainty factor as labor and defective products will be considered in this model.
Evaluation of Fatigue Life of Ultra-High-Strength Steel under Stress Corrosion Environment
Authors: Gu Kyoung Hee , Lee Ki Sik , Lee Gum Hwa , Nam Ki Woo
Published: June 2022

Ultra-high-strength steel (UHSS) structures are exposed to corrosive environments during service, and hydrogen-assisted cracking (HAC) may occur owing to stress corrosion cracking and hydrogen embrittlement. In this study, the HAC threshold stress intensity factor and fatigue life of UHSS steel were evaluated by applying stress in a corrosive environment to prevent structural fracture. For specimen with semicircular slits by electric discharge machining, fatigue limit was obtained by static fatigue test under corrosive environment. The fatigue limit of the crack specimen was evaluated by the fatigue limit of the experiment and HAC threshold stress intensity factor, and comparative evaluation was performed. On the surface of cracks, grain boundaries were embrittled by corrosion, and grains were clearly observed. Meanwhile, cracks in the surface direction propagated slightly, unlike cracks in the depth direction. The static fatigue limit of UHSS (SKD11:HV670) was determined to be 400 MPa, and the fatigue limit of the crack specimen could be evaluated. The experimental results agreed well with the evaluation results.
Efficacy of mechanical thrombectomy in stroke patients with large vessel involvement
Authors: Aghamiri Seyed Hossein , Mansouri Behnam , Mehrpour Masoud , Karani Seyed Meghdad Hoseini , Ghaffari Mehran , Lima Behnam Safarpour , Komlakh Khalil
Published: June 2022

Ischemic stroke is a common disease worldwide and leads to a significant rate of mortality and disability in patients every year, and imposes high costs on the health care system. The aim of this study was to evaluate the efficacy of the invasive method of mechanical thrombectomy for rapid intervention in ischemic stroke patients with large vessel involvement. Patients suspected of having a stroke, who were referred to Imam Hossein Hospital, were examined, and the diagnosis of stroke was confirmed. In the next stage, patients' MRS index was measured and the possibility of emergency thrombectomy was evaluated in patients. Patients who underwent thrombectomy were considered as the case group and the other patients were contemplated as the control group; then, the cases of the two groups were evaluated and compared. The mean age of patients was 66.63 ± 12.26 years. the use of emergency thrombectomy in the study group significantly reduced the MRS index of patients after 90 days (p <0.001), while a significant increase in the mean scores of the MRS index was seen in patients receiving pharmacological treatments. Also, there was no significant difference in terms of gender between the group of patients undergoing thrombectomy and the group receiving other treatments (p = 0.375). Emergency mechanical thrombectomy significantly reduces disability in stroke patients in the long term and can be a good alternative to conventional drug treatments.
Prevalence and antimicrobial resistance profile in Salmonella spp. isolates from swine food chain
Authors: Lauteri Carlotta , Festino Anna Rita , Conter Mauro , Vergara Alberto
Published: June 2022

The aim of this survey was to examine the prevalence and the antimicrobial resistance (AMR) of Salmonella spp. isolated from swine food chain. A total of 435 samples were collected: 360 from slaughterhouse (150 carcasses, 30 cecal samples, 180 environmental samples) and 75 from Italian traditional pork dry sausages. Thirty-six Salmonella were isolated and identified by Polymerase Chain Reaction (PCR): 13,3% (4/30) in fecal samples, 5,5% (10/180) in environmental samples, 7,3% (11/150) in carcasses, and 14,6% (11/75) in Italian traditional dry sausages. Salmonella serotypes were: S. Typhimurium (44,4%), S. Typhimurium monophasic variant (8,3%), S. Typhi (2,8%), S. Enteritidis (22,2%), S. Rissen (16,6%) and S. Derby (5,5%). Phenotypic and genotypic characterization of AMR Salmonella spp. isolates was executed through automatic system (VITEK 2, bioMèrieux) and PCR assays. Salmonella spp. showed phonotypical and genotypical resistance to at least one or more classes of antibiotic. All Salmonella spp. were resistant to aminoglycoside (amikacin and tobramycin) and gentamicin, 86,1% strains were resistant to tetracycline, 55,5% strains were resistant to ampicillin and piperacillin, 25% strains to trimethoprim, 5,5% strains to chloramphenicol, 2,8% strains to amoxicillin/ clavulanic acid, and nitrofurantoin. Among Salmonella isolates, the most detected AMR genes were catA for chloramphenicol (94,4%), nitrofuran nfsA (77.7%), nfsB (86,1%) and, for fluoroquinolone par C (100%) and gyrA (94,4%). This study reported epidemiological data regarding Salmonella spp. and AMR’s circulation in the swine food chain. This phenomenon (AMR) has critical repercussions on the final consumer health; therefore, it represents a crucial One-Health issue.
Micro-Politics and the Prospects for Convivial Conservation
Authors: Pandya Revati
Published: June 2022

This research article calls for explicit attention to micro-politics through engagement with a feminist intersectional lens for enabling convivial conservation. Convivial conservation provides a vision for equitable conservation through simultaneously pursuing structural change and addressing context specific micro-politics. This research article draws on feminist intersectional research and feminist political ecology to argue that convivial conservation needs to explicitly engage with the ways that intersections of class, gender, caste, and other identity positions shape the micro-politics of power around land rights and opportunities for benefitting from conservation interventions. It draws on findings from two forest villages near the Corbett Tiger Reserve in India to demonstrate the micro-politics that shape the variegated access and tourism dependencies experienced by different local residents. Engaging with learnings from implementation of the progressive Forest Rights Act (FRA) which intended to redress these issues, this analysis highlights that the FRA serves as both a cautionary and potentially transformative example for furthering the convivial conservation vision of local people's engagement with conservation areas.
Signet ring cell lymphoma of follicular type with BCL2 gene rearrangement
Authors: Mishra Pritinanda , Adhya Amit Kumar , Kar Madhabananda , Parihar Mayur , Samal Swagatika , Sable Mukund
Published: June 2022

A case of signet ring cell lymphoma of presacral lymph node is reported. The patient was diagnosed as follicular lymphoma on the basis of clinical and laboratory features, including immunohistochemistry (IHC) and gene rearrangement studies. Light microscopy examination showed neoplastic atypical cells with signet ring cell morphology in core biopsy of lymph node that stained for B-cell markers by IHC. In addition, the neoplastic cells expressed CD20, CD10, BCL-2, and BCL-6, indicating follicular center origin. Fluorescence in situ hybridization study demonstrated BCL2 gene arrangement. Especially in the case of deep-seated intra-abdominal lymph nodes with atypical presentation, the differential diagnosis arises with nonhemopoietic tumors, and this needs to be distinguished by specific immunostaining and gene arrangement studies.
Cyclin-dependent kinase inhibitor p21 and proliferative marker ki67 in colonic carcinoma
Authors: Kumar Sanjay , Singh Neha , Kataria Sant Prakash , Kandoi Shruti , Verma Meena , Sen Rajeev
Published: June 2022

Objective:

Tumor grade employed for colorectal cancer has long been based on the degree of differentiation, which is difficult to judge objectively. The aim of this study was to assess the immunohistochemical expression of p21 and ki67 and their correlation with the histological grading of colorectal carcinoma.

Materials and Methods:

A total of 45 biopsy specimens of colorectal cancer were pathologically reviewed and correlation of grade and differentiation of tumor was performed with immunostaining.

Results:

Ki 67 and p21 markers showed inverse relationship. An inverse relationship of p21 was found with tumor grade, differentiation, Dukes staging and lymph node status, whereas no correlation could be found between these parameters and ki67 expression.

Conclusion:

We found that p21 can be used to assess the grading and metastatic potential of colorectal carcinoma whereas increased Ki67 expression can help us in the diagnosis of malignancy.
Topical Herbal Therapeutic Formulation used in the Management of Oral Potentially Malignant Disorders – A Systematic Review
Authors: Dhanvanth M , Maheswari T N Uma
Published: June 2022

Background:

Oral potentially malignant disorders (OPMDs) are divided into two groups precancerous lesions, a benign lesion with morphologically altered tissue, which has a greater than normal risk of transforming into malignancy, and precancerous conditions, a disease or patient's habit that does not necessarily alter the appearance of local tissues but is associated with a greater or normal risk of precancerous lesion or cancer development in that tissue.

Aim:

This systematic review aims to evaluate the effectiveness of topical herbal therapeutics in the management of potentially malignant oral disorders.

Objective:

Primary objective was to evaluate the efficiency of tulsi, aloe vera, and turmeric in the management of OPMDs, and the secondary objective was to determine the herbal therapeutic response in patients with oral leukoplakia oral sub, mucous fibrosis, and lichen planus.

Data Sources and Search Methods:

The search was done using the MeSH [medical subject headings] terms and keyword search in the electronic databases, namely Pub Med and Google Scholar. The studies included in this systematic review were identified by a comprehensive search from the electronic search engines like Pub Med Advanced search (from April up to January 2021) and Google scholar. The search yielded 39 articles out of which 11 articles were only included based on the inclusion criteria.

Data Collection and Analysis:

All the studies included were based on the data extraction and analysis of the studies for quality. The outcome measure evaluated the reduction in burning sensation, mouth opening, and clinical resolution of the lesion.

Results:

A total of 39 articles were included in this systematic review from electronic searches using Pub Med advanced search and Google scholar.

Conclusion:

For management of oral submucous fibrosis topical aloe vera gel showed 90% of complete clinical response, oral lichen planus topical tulsi and turmeric gel showed 90% complete clinical response, and only two studies were conducted on oral leukoplakia which had a high risk of bias; hence, this systematic review does not yield to a piece of conclusive evidence for the management of oral leukoplakia using topical herbal therapeutics.
Ewing's Sarcoma of the Maxilla in an Adolescent Male – A Rare Case Report
Authors: Sharma Manisha Lakhanpal , Srivastava Siddharth , Uppal Mansimranjit Kaur , Martolia Garima
Published: June 2022

Ewing's sarcoma (ES) is an atypical malignant neoplasm of long bones rarely affecting the head and neck region. Here, we report a case of a 13-year-old male patient with a chief complaint of an unhealed socket and swelling in the right mid-facial region, following an extraction. Intraoral examination revealed an unhealed socket with respect to permanent maxillary right second molar region. Advanced imaging such as cone-beam computed tomography (CBCT) revealed an aggressive, expansive, osteolytic lesion involving the right posterior maxillary alveolus, extending into the maxillary sinus. Histopathology and tumor markers such as the cluster of differentiation (CD)99 were deterrent in the diagnosis.
Plasmacytoid Myoepithelioma Arising in Hard Palate – A Rare Case Report
Authors: Gaikwad Trupti V. , Chavan Mahesh S. , Khare Vikram V. , Gore Charusheela R.
Published: June 2022

Myoepithelioma, which is benign, is a salivary gland neoplasm representing 1.5% of all the neoplasms of salivary glands. The commonest location of its occurrence is parotid gland. In this condition, there is proliferation of myoepithelial cells arranged in cords, mantles, or nests. A 20-year-old woman presented with a well-circumscribed, asymptomatic swelling on the left half of the hard palate, which was gradually increasing in size for 10 years. A provisional diagnosis of pleomorphic adenoma was made. Computed tomography scan showed a well-defined soft tissue density lesion, which on histopathologic examination revealed a well-circumscribed, partially encapsulated neoplasm comprising monomorphic tumor cells in clusters and lobules with plasmacytoid characteristics. Therefore, it is necessary to consider myoepitheliomas also as one of the differential diagnoses while dealing with palatal swellings.
Determining the Probability of Malignant Transformation of Tobacco-Induced Oral Leukoplakia using Tissue p53 as a Prognostic Marker – A Cross-Sectional Study
Authors: Ramesh Bhargavi , Aswath Nalini , Shyamsundar Vidhya Rani
Published: June 2022

Context:

The concept of field cancerization necessitates substantiation of clinical assessment and histopathological examination by molecular markers. Molecular tumor biomarkers such as p53 protein overexpression aid in assessing the malignant transformation of such potentially malignant oral lesions.

Aim:

To identify the molecular changes in oral leukoplakia by studying the immunoexpression of tissue p53 and correlating it with the clinical and histological findings to establish an appropriate treatment plan.

Methods and Material:

Biopsy samples taken from 25 oral leukoplakia cases were subjected to histopathological and immunohistochemical analysis to determine the percentage positivity of p53 expression. Histopathological grading was based on dysplastic features and level of epithelial involvement. Dysplasia grading in IHC sections was estimated by p53% positivity in the cells. The obtained data were subjected to statistical analysis.

Results:

24 samples were considered for statistical analysis due to the loss of epithelium in the IHC section of one sample. The results showed a statistically significant association between histopathological and IHC grading of dysplasia with a P value less than 0.05 in Fisher Exact test.

Conclusion:

Increased expressions of p53 in potentially malignant oral lesions are proportional to the risk of malignancy. The gold standard histopathological result does not reveal the molecular abnormality associated with a potentially malignant oral lesion. Therefore molecular analysis of such lesions will aid in the effective prevention of oral cancer.
Matrix Method of Determining Optical Energy Bandgap of Natural Dye Extracts
Authors: Yerima J. B. , Babangida A. , Ezike S. C. , Dunama W. , Ahmed A. D.
Published: June 2022

In this paper, a total of fourteen dye extracts from different plants’ parts (flowers and fruits) were extracted. Absorbance of light by dye extracts with 5%, 10% and 20%concentrationsweremeasured using a UV-Vis spectrophotometer at different wavelengths. A system of linear equations in terms of wavelength and absorbance without film thickness was developed and solved using MATLAB software. Also, optical energy bandgap (Eg) obtained experimentally are at range of 1.77- 2.76 eV. From the solutions of the system of equations, the (Eg) of the natural dyes were obtained. The results show all the dye extracts have (Eg) in the range 1.34-2.09 eV which falls within the range of UV and IR portions of the electromagnetic spectrum. Also, the results reveal that sunflower (Helianthus) dye has the smallest (Eg) of 1.34 eV and guava (Guajava) peel dye with the higher (Eg) of 2.09 eV. This means Helianthus dye absorbs more light over a wider part of the electromagnetic spectrum and the easier electron transfer from its valence band to the conduction band. The values obtained via matrix method are in agreement with the experimental values with slight deviation, hence this validates the matrix method of obtaining optical energy bandgaps.
Determining the Causes of Internally Displaced Persons (IDPS) and Counselling for Social and Psychological Adjustment in Plateau State, Nigeria
Authors: Godfrey R. Dungum , Tafida M. Adjei
Published: June 2022

This study investigated the main causes of internally displaced persons (IDPs) and proffered counselling intervention for social and psychological adjustment in Plateau state. The survey research design was adopted for this study. A questionnaire was used to elicit information from sixty (60) respondents who were randomly selected from the three camps for the study. 13 factors were presented to the respondents as to determine the main factors that are responsible for internally displaced persons in Plateau State, Data were analyzed and results indicated that the main causes of Internally displaced people in Plateau State include: herdsmen/farmers’ conflicts, Boko Haram activities, Religious crises, Political conflict, Communal conflict, and disparity in political appointment. It was also found that the following factors are harmful and responsible for displacement of people from their homes in plateau state, which include: Security agents who cannot protect properties and harmless civilians, Natural disasters, and lack of employment. Based on the findings of this study, recommendations were made towards improving the enormous challenges arising from the internally displaced persons in Plateau state and Nigeria at large.
Fulvestrant, an estrogen receptor inhibitor, relieves postoperative hemorrhoid edema via up-regulation of miR- 424-5p
Authors: Meng Fanyu , Chen Xinghua , Liu Huajiang , Zhang Lei , Yu Ting , Xie Minning
Published: June 2022

Purpose: To investigate estrogen receptor (ER) expression in postoperative hemorrhoid edema tissues, and the likely mechanism involved in fulvestrant-mediated reduction of postoperative hemorrhoid edema.Methods: One hundred and eighty-five patients admitted to Jinshan Hospital of Fudan University, Shanghai who accepted hemorrhoidectomy were enrolled in this study. Primary cells were extracted from the anal margin tissues of patients for the determination of changes in ERα and vascular endothelial growth factor (VEGF). In vitro cellular experiments were performed in primary vascular endothelial cells to verify whether ER promoted postoperative perianal edema via the miR-424-5p estrogen receptor α gene (ESR1) axis. The cells were exposed to Fulvestrant, estradiol, and miR-424-5p mimic. Changes in expressions of ERα and VEGF were determined.Results: Fourteen patients (7.57 %), comprising 2 males (2.60 %) and 12 females (11.1 %), developedpostoperative anal margin edema. There was a significant difference in the incidence of postoperative anal edema between males and females (p < 0.05). Both immunohistochemistry and immunoblotting revealed markedly higher ERα levels in postoperative anal edema tissues than in preoperative tissues (p < 0.05). Moreover, ERα level was regulated by estradiol, and miR-424-5p targeted the estrogen receptor α gene (ESR1).Conclusion: Estradiol inhibits miR-424-5p through ERα in perianal tissues after hemorrhoid surgery. It increases VEGF and promotes perianal edema. However, fulvestrant inhibits ERα, thereby reducing VEGF expression and mitigating postoperative hemorrhoid edema, and therefore, has potential application for the management of postoperative hemorrhoid edema.
Potential Economic and Environmental Benefits of Faecal Sludge Derived Compost and Char Briquettes: The case of Dar es Salaam, Tanzania
Authors: Mkude Isabela T , Kimwaga Richard , Gabrielsson Sara
Published: June 2022

The concept of resource recovery, particularly from waste has recently gained much attention and popularity. The aim of this study was to quantify the potential economic and environmental benefits of recovering nutrients and energy from faecal sludge (FS). The empirical data were collected from three unplanned settlements of Dar es Salaam City at Keko, Kipawa and Manzese. Two scenarios were developed to recover nutrients and energy. The estimations of potential amounts of compost and char briquettes were performed by using the resource value mapping (REVAMP) tool. Results from REVAMP indicated daily economic benefits across the study areas ranging between 680 and 950 USD for energy and up to 7,000 USD for nutrients recovered, based on the faecal sludge composition. In general, FS derived compost was found more profitable than FS derived briquettes. The analyzed environmental benefits include saving the estimated to 5 hectares of forest area from being cut when substituting the use of wood charcoal with FS-derived briquettes. Since the composting process resulted to be more profitable option between the two, this study recommends the adoption and scaling up. However, guidelines and standards should be developed for proper practices.

Keywords: Faecal sludge; resource recovery; resource value mapping; briquettes; compost; economic benefits; environmental benefits
Modelling Internet Traffic Streams with Ga/M/1/K Queuing Systems under Self-similarity
Authors: Popoola Judoka , Popoola Olusogo J , Olaniran Oyebayo R
Published: June 2022

High-intensity concurrent arrivals of request packets in Internet traffic can cause dependence of event-to-event-times of the requests being served, which causes non-memoryless, modelled with heavy-tail distributions unlike common known traffics. The performance of Internet traffic can be examined using analytical models for the purpose of optimizing the system to reduce its operating costs. Therefore, our study examined a Ga/M/1/K Internet queue class (Gamma arrival processes, Ga; with memoryless-Poisson service process, M; a single server, 1, and K waiting room) and proposed specific derivations of its performance indicators. Real-life data of a corporate organisation Internet server was monitored at both peak and off-peak periods of its usage for Internet traffic data analysis. The minimum ‘0’ in the arrival process indicates self-similarity and was assessed using Hurst parameter, H, and their (standard deviation). ‘H’ > 0.5 arrival process in the peak period only, indicates self-similarity. Performance of Ga/M/1/K was compared with various queuing Internet traffic models used in existing literatures. Results showed that the value of the waiting room size for Ga/M/1/K has closest ties with true self-similar model at peak-periods usage of the Internet, which indicates possible concurrent arrival of clients' requests leading to more usage of the waiting room, but with light-tailed queue model at the off-peak periods. Therefore, the proposed Ga/M/1/K model can assist in evaluating the performance of high-intensity self-similar Internet traffic.     

Keywords: Internet traffic; self-similarity; Ga/M/1/K model; gamma distribution
Avian Use of Habitat Patches Dominated by Exotic Leucaena leucocephala or Native Tree Species in Urban Dar es Salaam, Tanzania
Authors: Werema Chacha , Wilson Charles
Published: June 2022

There has been an incursion of an exotic Leucaena leucocephala in disturbed areas and into habitat patches of native tree species in some areas in Tanzania. However, the impacts of this exotic tree on native biodiversity are not well understood. We assessed bird use of habitat patches dominated by L. leucocephala in comparison to patches of native tree species  at the University of Dar es Salaam main campus, Tanzania, by comparing bird species richness, abundance and diversity using mist netting. Based on the same mist netting efforts in each habitat patch type, patches of native trees had significantly higher overall diversity (t = 1.999, df = 293.64, p < 0.05) and abundance (χ2 = 40.525, df = 1, p < 0.001) of birds than those dominated by the exotic L. leucocephala and significantly greater abundance of forest-dependent species (χ2 = 10.938, df = 1, p < 0.001) and forest visitors (χ2 = 15.258, df = 1, p < 0.001). The similarity in bird species between the two habitats was 0.658 indicating that many bird species occurred in both habitat types. The lower diversity and overall abundance of  birds in the patches dominated by the exotic plant suggest that it does not provide appropriate habitat for many bird species, and further spread of this exotic will be detrimental to the local avifauna.

Keywords: Birds, diversity, native tree species, exotic tree species, Leucaena leucocephala.
Mizoandria. Wokół eseju Pauline Harmange Moi les hommes, je les déteste
Authors: Kłosińska Krystyna
Published: June 2022

Misandry. Around Pauline Harmange’s Essay I Hate Men The object of reflection is Pauline Harmange’s famous essay, I Hate Men (2020). I start from the perturbations it caused on the political scene, then try to situate it on the French map of feminist and anti-feminist movements since the 1970s, asking about the place from which the young essayist speaks. I consider the central issue to be the misandric discourse she has activated, and around it I (re)construct a spectrum of issues that, in her view, illuminate it. I trace the “archaeology” of the word misandry, which is not anchored in the everyday reality, including the academic one. I ask about its function by juxtaposing two contradictory perspectives: Harmange’s feminist one and the anti-feminist one whose activists proclaim misogynist and sexist slogans. The symmetrical or asymmetrical approaches to misandry and misogyny are also arranged at these poles. Harmange, while cultivating misandric attitudes among women, consistently enumerates the benefits they should derive from misandry.
Nawrócenie synodalne w rozumieniu papieża Franciszka
Authors: Szałanda Tomasz
Published: June 2022

Nawrócenie synodalne jest powrotem Kościoła do wspólnotowego działania misyjnego – głoszenia Ewangelii wszędzie. Polega ono na zmianie myślenia o Kościele, zmianie sposobu bycia w Kościele i zmianie przeżywania Kościoła. Ta zmiana winna się dokonywać przez spotkanie wspólnoty, słuchanie Ducha Świętego i siebie nawzajem, by dobrze rozeznać, co dzisiaj Paraklet mówi do Kościoła.

Synodal conversion according to pope Francis

Synodal conversion is the return of the Church to community missionary activity – to proclaim the Gospel everywhere. It consists in changing the way of thinking about the Church, changing the way of being in the Church, and changing the way of perceiving the Church. This change should be made by meeting the community, listening to the Holy Spirit and one another, in order to discern well what the Paraclete is saying to the Church today.
On Q-Polynomial Shilla Graphs with b=6
Authors: Махнев А.А. , Чжиган В.
Published: June 2022

{Графом Шилла называется дистанционно регулярный граф $\Gamma$ диаметра 3,имеющий второе собственное значение $\theta_1$, равное $a = a_3$. В этом случае $a$ делит $k$и полагают $b = b(\Gamma) = k/a$. Далее, $a_1 = a - b$ и $\Gamma$ имеет массив пересечений$\{ab,(a + 1)(b - 1), b_2; 1, c_2, a(b - 1)\}$. И.~Н. Белоусов и А. А.~ Махнев нашли допустимые массивы пересечений $Q$-полиномиальных графов Шилла с $b=6$:$\{42t,5(7t+1),3(t+3);1,3(t+3),35t\}$, где $t\in \{7,12,17,27,57\}$,$\{312,265,48;1,24,260\}$, $\{372,315,75;1,15,310\}$, $\{624,525,80;1,40,520\}$, $\{744,625,125;1,25,620\}$,$\{930,780,150;1,30,775\}$, $\{1794,1500,200;1,100,1495\}$ или$\{5694,4750,600;1,300,4745\}$.В работе доказано, что графы с массивами пересечений $\{372,315,75;1,15,310\}$, $\{744,625,125;1,25,620\}$ и $\{1794,1500,200;1,100,1495\}$ не существуют.
On the Issue of Implementing Criminal Law Axioms in the Form of Presumptions
Authors: Кабанов В.М.
Published: June 2022

В статье проведен анализ процесса реализации уголовноправовой аксиомы в форме презумпции, рассмотрены понятия правовой аксиомы и презумпции, приведены примеры закрепления в уголовном праве конкретных правовых аксиом в виде презумпций. Автором сделан вывод о том, что уголовно-правовая аксиома может быть реализована в форме правовой презумпции лишь в косвенном виде, в связи с чем существование такой аксиомы может быть установлено только путем применения той или иной нормы к процедуре грамматического и логического толкования.

The article analyzes the process of implementing criminal law axioms in the form of presumption, considers concepts of legal axiom and presumption, provides examples of consolidating specific legal axioms in the form of presumptions in criminal law. The author concludes that the criminal law axiom can be implemented in the form of a legal presumption only indirectly, and therefore the existence of such an axiom can be established only by applying one or another norm to the procedure of grammatical and logical interpretation.
Violation of the Accused Person’s Right to Defense: Who Is to Blame?
Authors: Черемисина Т.В.
Published: June 2022

В статье исследуются дефиниции следственных ошибок и причины их появления в практической деятельности субъектов уголовного процесса. Рассмотрены случаи возвращения уголовных дел судами прокурору в случае обнаружения нарушений права обвиняемого на защиту стороной защиты, а не обвинения. Приводятся актуальные примеры возвращения уголовных дел для устранения препятствий к их рассмотрению судами в порядке ст. 237 УПК РФ. Следователям предлагаются рекомендации по действиям после выявления нарушений уголовно-процессуального закона со стороны защитника. Автор обращает внимание на необходимость привлечения адвокатов к дисциплинарной ответственности при выявлении нарушений законодательства

The article examines definitions of investigative errors and reasons for their appearance in practical activities of the subjects of criminal proceedings. It considers cases of the return of criminal cases by the court to the prosecutor, in case the accused person’s right to defense is violated by the defense, and not by the prosecution. Actual examples of the return of criminal cases to eliminate obstacles to their consideration by the court in accordance with Article 237 of the Criminal Procedural Code of the Russian Federation are given. The work presents recommendations for investigators regarding their actions after detection of violations of the criminal procedural law by the defender. The author draws attention to the need to bring lawyers to disciplinary liability when detecting violations of the law
DESIGN AND OPERATION FEATURES OF FRICTION DISCS
Authors:   Joint Institute of Mechanical Engineering of the NAS of Belarus, ANTONYUK Vladimir E.
Published: June 2022

The features of changes in geometric parameters of friction discs during operation are described, in particular, the main type of disc warping in the dish-shaped form. Causes of dish-shaped form occurrence are considered. It is offered to estimate a tendency to a deflection in a dish-shaped form of disc by relative width of a working surface of frictional discs, that is as a relation d/D of internal diameter d to external diameter D, and also on a relation h/rср, width h of a disc body to average radius rср. By results of calculation of disc tendency to temperature rise and to deformation, the optimum relative width of a working surface of frictional discs is defined as the relation d/D = 0.675. It is suggested to classify discs with d/D ˃ 0.675 as “narrow” discs, and with d/D ˂ 0.675 as “wide” discs. Peculiarities of operation of “narrow” and “wide” discs are formulated and recommendations for their use in different friction units are given. The values of an allowable deviation from flatness of disc working surfaces are given and technological possibilities of achieving accuracy by deviations from flatness are determined using dynamic stabilization. Information about the results of dynamic stabilization application in manufacturing of friction discs and clutch discs is presented. For realization of dynamic stabilization of all types of discs two schemes of loading are offered: with disc rotation between rollers located in staggered order, and without disc rotation on the basis of cogged bending. The promising outlook of dynamic stabilization technology is proved in manufacturing of discs for wheel and tracked vehicles of civil and special purposes.
FEATURES OF APPLYING STEEL AND TITANIUM COATINGS BY HYPERSONIC METALLIZATION
Authors:   JSC Belaruskali, KARPETS Maksim N. , SOSNOVSKY Aleksey V. ,   Joint Institute of Mechanical Engineering of the NAS of Belarus
Published: June 2022

Currently, methods of thermal spraying are widely used to restore and harden various worn parts of machines. In most cases, metal and composite wires are used as materials for gas-thermal coating applying methods. As a rule, metal coatings applied by thermal spraying have lower strength characteristics than cast materials. An important factor characterizing the possibility of using metal coatings in various industries is their density and adhesion strength of coatings with the base metal. In this paper, the structure and density of coatings, as well as the adhesion strength of coatings made of steel and titanium wires deposited by hypersonic metallization were studied.
METHOD SELECTION OF DATA PROCESSING AND RECEIVING LONGITUDINAL PROFILE OF THE ROAD, VEHICLE MOVEMENT MODE USING GPS (GNSS RECEIVER)
Authors:   OOO “Midivisana”, MISHUTA Dmitriy V. , MIKHAILOV Vladimir G. , SIRAI Maksim V. ,   Ministry of Defence of the Republic of Belarus
Published: June 2022

The existing methods are analyzed for receiving and processing data from a GNSS receiver obtained on a moving car in the form of messages in degrees of latitude and longitude and converting them into meters. An accuracy assessment was carried out to determine the location and movement of machinery using various methods. The method is proposed for data processing and obtaining the longitudinal profile of the road, the car velocity (mode) using a GNSS receiver (according to the parameters of the velocity and altitude of a moving object on the surface of the Earth). It is revealed that the considered foreign methods of location determination in relation to the CIS give significant discrepancies (up to 2 times), which is associated with the use of various systems of reference points in the CIS and abroad, including in cartography, electronic maps. It is established that when estimating the distance covered by the difference in the displacements of two points of the positioning projections and their summation for small quantization increments (8–20 m, depending on velocity and frequency), the considered methods can lead to a discrepancy of up to 30–47 %. It is proposed to use the simplified linear formula lat_m = 112297,6196∙Ddec lat, lon_m = 63215,444 Ddec lon in the territory of the Republic of Belarus when determining relative distances and linking to maps. It has been found that to obtain a longitudinal profile of the road, depending on the distance covered, the mode of movement of vehicles, military machinery, unmanned aerial vehicles, it is more correct to use GNSS receiver data on velocity and altitude, providing a minimum error (0.15 %), which is confirmed by the nature of the change h = f(l), υa = f(l) and indicates the correctness of the proposed method. Also, when modelling the car movement, it is necessary to take into account road factors affecting the driving mode.
Las TIC una aproximación teórica
Authors: Garófalo-García Ruth Noemí , Avellaneda-Callirgos Lolo , León Julio César Tay , Vilchez Shirley Tatiana Bustamante , García Angelo Guerrero , Melendez Ingrid Milagros Albán , Dávila Alberto Lachos , Luque Celso Huanca
Published: June 2022

El objetivo del presente artículo de revisión es identificar las aproximaciones teóricas elaboradas acerca de las TIC en las universidades del Ecuador y América Latina. El método utilizado ha sido el teórico, básico y sistemático y para fundamentar y sustentar la literatura a utilizarse se han seleccionado bases de datos indexadas y de reconocimiento científico internacional que cumplan con los estamentos establecidos por organismos internacionales de investigación, dichas revistas en las cuales se fundamenta este estudio fueron Erick, Scielo,  Google Académico, Revista Espacios, Scopus, Alteridad y  Redalyc, todas estas reconocidas mundialmente y pertenecen a  los países Latinoamericanos, Europa y no podría faltar 2 revistas ecuatorianas. Así mismo se seleccionaron 50 artículos de los cuales 20 fueron elegidos por tener una relación directa con la variable del presente estudio. Los años considerados oscilan entre el 2016 hasta el 2020. Resultados, Se considera también que el bagaje de información que se encontró en la red es amplia y muy nutrida, existen muchos artículos actualizados que hablan de las TIC y el uso que las universidades en el Ecuador y América Latina le están dando. Conclusiones, las TIC en la actualidad se han convertido en potenciales de aprendizaje, investigación y estudio.
A Double-Blind, Randomised, Placebo-Controlled Trial of EMLA® Cream (Eutectic Lidocaine/Prilocaine Cream) for Analgesia Prior to Cryotherapy of Plantar Warts in Adults
Authors: Lee Siew Hui , Pakdeethai Janthorn , Toh Matthias PHS , Aw Derrick CW
Published: June 2022

Introduction: Cryotherapy with liquid nitrogen is an effective, safe and convenient form of treatment for plantar warts. EMLA® cream (eutectic mixture of lidocaine 2.5% and prilocaine 2.5%) is a topical local anaesthetic agent that has proven to be effective and well tolerated in the relief of pain associated with various minor interventions in numerous clinical settings. Materials and Methods: In a single-centre, double-blind, randomised placebo-controlled study, 64 subjects were randomised into 2 groups. The subjects had a thick layer of EMLA® cream or placebo cream applied to pared plantar wart(s) and onto the surrounding margin of 1 mm to 2 mm under occlusion for 60 minutes prior to receiving cryotherapy. The pain of cryotherapy was evaluated by the subjects using a self-administered Visual Analogue Scale (VAS) immediately after the cryotherapy. Results: There was no statistical difference between the mean VAS score for EMLA® cream (47.0 ± 21.4 mm) and placebo (48.9 ± 22.0 mm). Those with more than 1 wart had a significantly higher VAS score than those with only 1 wart (59.1 ± 21.8 vs. 44.3 ± 20.4, P <0.05) but this did not affect the therapeutic effect of EMLA® cream prior to cryotherapy. Conclusion: We conclude that the application of EMLA® cream prior to cryotherapy does not reduce the pain associated with cryotherapy.

Key words: Anaesthetic, Pain, Wart
Physiologically-guided Balanced Resuscitation: An Evidence-based Approach for Acute Fluid Management in Paediatric Major Trauma
Authors: Kua Jade PH , Ong Gene YK , Ng Kee Chong
Published: June 2022

Trauma is a major cause of death, and haemorrhage represents an important target for improving outcomes after severe injury. Volume replacement with crystalloids in resuscitation might become harmful in large amounts because of coagulopathy. A fine balance must be achieved between haemodynamic and haemostatic resuscitation. Permissive hypotension refers to permitting some degree of hypotension in such adult patients in an attempt to attain this fine balance. For patients who require a significant volume of blood product resuscitation, the term ‘massive transfusion protocol’ (MTP) is used. There is very little data on transfusion protocols for paediatric trauma patients, and children respond to hypovolemic shock in a different physiological manner compared to adults. Hence, concepts such as permissive hypotension may not be appropriate when treating children involved in major trauma. We recently embarked on a plan to streamline the management of blood transfusion in massive bleeding during paediatric trauma, to reduce the logistical problems associated with the transport of blood products from the blood bank to the patient. From this, we evolved a MTP for paediatric major trauma. Nonetheless, further studies will be needed to see if there is indeed improved outcome after MTP in paediatric major trauma as current evidence is extrapolated from adult studies. Key words: Compensated versus decompensated shock, Damage control resuscitation, Massive transfusion protocol, Permissive tachycardia
Spectrum and Burden of Movement Disorder Conditions in a Tertiary Movement Disorders Centre—A 10-Year Trend
Authors: Eu Kar Mun , Tan Louis CS , Tan Amanda RJ , Seah Irene SH , Lau Puay Ngoh , Li Wei , Au Wing Lok , Tay Kay Yaw
Published: June 2022

Introduction: The precise burden of movement disorder conditions in our movement disorders centre is unclear. This study investigated the clinical burden of the Movement Disorders Clinic (MDC) in National Neuroscience Institute (NNI) over 10 years, aiming to identify the burden and spectrum of movement disorders conditions, to facilitate future resource allocation. Materials and Methods: We identified all patient visits from January 2002 to December 2011 at MDC from the Movement Disorders (MD) database using a standardised data collection form. Results: There was a linear increase in the clinical burden of MDC during this period. Parkinsonism comprised 71.6% of this clinical burden of which 84.8% were Parkinson’s disease (PD) patients. Dividing the incident cases of MD conditions into two 5 years’ blocks, the proportion of PD cases had not changed. There was significant increase in time to diagnosis for PD, hemifacial spasm and dystonia. Conclusion: There was nearly 4-fold increase in the burden of movement disorders conditions in our tertiary condition within a decade. However, we did not find increasing proportion of PD cases which would be in line with an ageing population. This could be due to the fact that we are still in the early stages of an ageing population and we postulate that this proportion will go up in the future. The increased time to diagnosis may indicate increasing waiting time to see a movement disorders specialist and that current outreach effort to promote awareness may not be reaching its target audience. The upward trend of clinical burden indicates a need for increased resource allocation to cope with demand for movement disorders services. Key words: Clinical burden, Movement disorder, Parkinson Disease, Tremor
Suicidal Ideation, Suicidal Plan and Suicidal Attempts Among Those with Major Depressive Disorder
Authors: Subramaniam Mythily , Abdin Edimansyah , Seow Esmond LS , Picco Louisa , Vaingankar Janhavi Ajit , Chong Siow Ann
Published: June 2022

Introduction: The aims of the study were to identify the prevalence and sociodemographic and clinical correlates of suicidal behaviours using data from a cross-sectional survey among those with major depressive disorder (MDD) in Singapore. Materials and Methods: The Singapore Mental Health Study (SMHS) was a cross-sectional epidemiological study that surveyed Singapore residents (Singapore citizens and permanent residents) aged 18 years and above. The assessment of mental disorders was established using version 3.0 of the Composite International Diagnostic Interview (CIDI 3.0). For the purposes of this study, suicidal behaviour was assessed by questions which were asked to respondents who answered positively to the screening questions in the CIDI 3.0 “Depression” module. Results: The prevalence of suicidal ideation, plan and attempt among those with lifetime MDD was 43.6%, 13.7% and 12.3%, respectively. We found that suicidal ideation, plan and attempt were significantly associated with ethnicity, education and income. The rate of those who had sought some professional help was higher among those with suicidal plan (71.7%) and attempt (72.3%) as compared to those with suicidal ideation (48.7%) and those with MDD but no suicidal behaviour (29%). Conclusion: Individuals with MDD and suicidal behaviour do differ from their non-suicidal counterparts as they have a different sociodemographic and clinical profile. There is a need for more research and a better understanding of this population which in turn could lead to the development and implementation of relevant interventions.

Key words: Composite International Diagnostic Interview, Depression, Prevalence, Singapore Mental Health Study, Suicidal behaviour