bluuebunny/crossref_metadata_2025 huggingface dataset:
The Self-Concept of Students Receiving Bidik Misi Scholarships at University of Jember
Authors: Garniasih Belly , Jannah Raudlatul
Published: October 2021

One of the scholarship programs at the University of Jember, which annually provides a lot of quotas, is a scholarship through the Bidikmisi program, which is given to students who come from economically low-income families and a good history of achievement. As it is known that ideally, Bidikmisi students must behave, appear, and act according to the definition of Bidikmisi scholarship itself to prevent misunderstandings in the use of scholarship funds. But still, some Bidikmisi students at Jember University do not display the definition of 'ideal.' From this phenomenon, a question arises about 'Self-Concept of Bidikmisi Students at Jember University.' In this study, researchers used a qualitative descriptive approach, which aims to obtain information about the self-concepts of Bidikmisi students at Jember University. The theory used is symbolic interactionism by George Herbert Mead, where the theory explains that a person is seen as an actor who interprets, evaluates, defines, acts, and tells about the use of symbols as a form of interpretation in one's interactions with others or with groups. The symbols used cold become in the form of verbal or nonverbal. The results showed that there were two kinds of Bidikmisi students' self-concepts, namely positive concepts and negative concepts. Positive self-concept, namely (1) making parents proud, (2) getting high achievements and aspirations, (3) being responsible. On the other hand, negative self-concepts are (1) feeling inferior (2) overly confident.

Keywords: self-concept, Bidikmisi students, positive concepts, negative concept

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Shintaviana, Fransisca Vivi. 2014. Konsep Diri Serta Faktor-Faktor Pembentuk Konsep Diri Berdasarkan Teori Interaksionisme Simbolik (Studi Kasus Pada Karyawan Kantor Kamahasiswaan, Alumni Dan Campus Ministry Universitas Atma Jaya Yogyakarta. Fakultas Ilmu Sosial Dan Ilmu Politik Universitas Atma Jaya Yogyakarta. E-journal.uajy.ac.id.id/5780/ (diakses pada 17/09/2017).
The Articulation of Healthy Water Closet Program in Kabuaran Village of Bondowoso: Analysing Society’s Behavioural Change in Defecation
Authors: Nisa Wardani Khoirun , Handayani Baiq Lily
Published: October 2021

The people in Kabuaran village used to defecate haphazardly. Since a sanitation program for healthy closet was promulgated, the people have been used to using water closet. To date, the village has been renowned as Open Defecation Free (ODF) Village, which is national award endowed to an area where the poeple no longer defecate haphazardly. The present study applied qualitative approach. The paradigm founded the study was criticism paradigm, coupled with the theory of Hegemony and Gramsci domination, adopted from Marx. The research findings evinced that the public behavioural change represented government’s control, actualized by local government. The synergy was a structure operationalized for positive behavioural change to stop haphazard defecating. Numerous innovations and initiatives were carried out by the village government, be it providing public toilet, clean water program, and water closet provision. It was at this juncture that domination mechanism was at work. In this regard, the village government accidentally involved traditional intellects, religious figures, to take part in accruing public awareness, which was done in hegemonic manner through regular Al-Qur’an recital.

Keywords: Behavioural change, domination, hegemony, traditional intellects.

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Rio, Sutanto Boby. 2015. Perilaku Masyarakat dalam Pemanfaatan Sarana Mandi Cuci Kakus (MCK): Studi Deskriptif Warga Desa Candijati Kecamatan Arjasa Kabupaten Jember. Universitas Jember: Jurusan Kesejahteraan Sosial.

Munthe, Hadriana Nurhaeni. 2007. Modernisasi dan Perubahan Sosial Masyarakat dalam Pembangunan Pertanian: Suatu Tinjauan Sosiologis. Medan: Universitas Sumatera Utara. Jurnal Harmoni Sosial Volume II No. 1.
Construction of Knowledge about Sholawat among "Bhenning" Recitation Members in Situbondo
Authors: Islamiyah Shofiatul
Published: October 2021

This study explains the construction of knowledge among members of the Sholawat Bhenning Community in Situbondo. By using social construction theory, this research describes the reality of the community based on the experience of the Bhenning prayer members. The research method used was qualitative, with in-depth interviews toward members of Sholawat Bhenning. The results of this study are the participation of members in the prayer activities carried out by the Bhenning group has changed bad behavior into good behavior. Members have many reasons to join the Sholawat Bhenning community. 1) Members want to learn about theater; 2) Members were fascinated by Karisma Kyai Aza Ibrahimy, 3) Members wished to gain knowledge from the group of Sholawat Bhenning; 4) members wanted to get merit from Allah Subhanahu wata'ala. Finally, their participation was supported by their friends.  Keywords: "Bhenning" prayer, Social Construction, youth, motivation involved, behavior change

Referensi:

Afifah, Latifatul. 2014. Eksistensi Pengajian Nurul Hidayat Dalam Meningkatkan Perilaku Sosial Keagamaan Remaja di Desa Trosono Kecamatan Sekaran Kabupaten Lamongan. Skripsi.UIN Sunan Ampel Surabaya

Alfina, Citra 2017. Perilaku Beragama Masyarakat Urban di Kawasan Ampel Surabaya. Skripsi. UIN Sunan Ampel Surabaya

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Praktik Agensi Masyarakat Desa Nglurup Dalam Program Pengelolaan Hutan Bersama Masyarakat (PHBM)
Authors: Handayani Baiq Lily , Akhbar Bobby
Published: October 2021

Lembaga Masyarakat Desa Hutan Argo Mulyo sudah ada sejak tahun 2006 lalu, lembaga tersebut dibentuk oleh pihak Perhutani melalui program Pengelolaan Hutan Bersama Masyarakat (PHBM). Tujuan dari penelitian ini untuk mengetahui serta menjelaskan tentang praktik agensi masyarakat Desa Nglurup dalam pengelolaan hutan bersama masyarakat. Adapun metode penelitian yang digunakan dalam penulisan karya ilmiah ini adalah kualitatif deskriptif dengan pendekatan deskriptif naratif. Untuk lokasi penelitian, peneliti mengambil setting di Desa Nglurup Kabupaten Tulungagung. Teknik penentuan informan yang dipakai oleh peneliti menggunakan teknik purposive yang dianggap relevan dengan masalah penelitian tersebut. Metode pengumpulan data menggunakan wawancara, observasi lapangan serta dokumentasi. Adapun uji keabsahan data yang dipakai yakni teknik triangulasi data. Hasil penelitian tersebut keterlibatan praktik agensi masyarakat dalam kegiatan penanaman lahan hutan, masyarakat berperan dalam kegiatan tersebut secara sukarela sebagai upaya mereka untuk melestarikan hutan melalui kegiatan penanaman bibit di lahan hutan. Praktik agensi masyarakat dalam pengelolaan lahan hutan yakni mereka pada umumnya menggarap lahan hutan produksi milik Perhutani. Praktik agensi masyarakat dalam pengelolaan kawasan wisata hutan.

Kata kunci: PHBM, pelestarian hutan, praktik agensi
Dampak Sosial dan Ekonomi Kunjungan Wisata di Desa Wisata Organik Lombok Kulon, Bondowoso
Authors: Cahyani Larasati Tiara , Ganefo Akhmad
Published: October 2021

Penelitian ini dilatarbelakangi oleh berkembangnya pengelolaan Desa Wisata Organik Lombok Kulon yang menggunakan konsep CBT dan mampu menarik wisatawan baik lokal maupun mancanegara, serta menimbulkan beberapa dampak dalam kehidupan masyarakat setempat. Adanya kunjungan dari wisatawan ke Desa Lombok Kulon tersebut jelas menimbulkan beberapa dampak bagi kehidupan masyarakat setempat. Artikel ini akan membahas tentang dampak sosial dan ekonomi dari kunjungan wisata di Desa Wisata Organik Lombok Kulon bagi masyarakat setempat. Teori yang digunakan dalam penelitian ini adalah teori dampak pariwisata yang dikemukakan oleh Erik Cohen. Penelitian ini pun menggunakan metode kualitatif deskriptif dengan teknik pengumpulan data berupa observasi, wawancara, dokumentasi, serta studi pustaka. Temuan dalam penelitian ini adalah munculnya dampak sosial dan ekonomi kunjungan wisata di Desa Wisata Organik Lombok Kulon, Bondowoso bagi masyarakat setempat. Dampak sosial dan ekonomi yang ditimbulkan antara lain : (1) Meningkatnya produksi kerajinan Desa Lombok Kulon, (2) Terbukanya lapangan pekerjaan baru bagi masyarakat,(3) Dampak terhadap stratifikasi dan mobilitas sosial, (4) Munculnya antusias masyarakat untuk melestarikan kesenian lokal, (5) Dampak terhadap dasar organisasi, dan (6) Munculnya antusias masyarakat terhadap Bahasa Inggris.

Kata Kunci: Dampak Sosial, Dampak Ekonomi, Dampak Pariwisata, Desa Wisata
Pengaruh Usia Dan Pendidikan Terhadap Implementasi nisiasi Menyusu Dini (IMD) Pada Pasien Post Sectio Caesarea
Authors: Parela Ningsih Meylina , Soesetijo FX. Ady , Rokhmah Dewi
Published: October 2021

Early initiation of breastfeeding (EIBF) in post sectio caesarea patients is the process of breastfeeding the baby to his mother immediately after birth by placing the baby on the mother's chest or abdomen so that skin-to-skin contact occurs and letting the baby find the mother's nipple and then breastfeed until satisfied. The benefits of IMD are very large for mothers and babies including accelerating the production of colostrum as a baby antibody so as to prevent infection, prevent hypothermia and hypoglycemia and prevent anemia due to bleeding after delivery. IMD becomes important to be carried out both for mothers with normal labor and with the act of sectio caesarea. This study aims to determine the effect of maternal age and education on the implementation of early initiation of breastfeeding (IMD) in post sectio caesarea patients. This type of research was analytic observational with cross sectional design. Data obtained from primary data 99 respondents by filling out a questionnaire and direct observation. The research site at Bina Sehat Jember Hospital in April 2021. Data obtained from the primary data of 99 respondents by filling out questionnaires and making direct observations. Data analysis used is bivariate analysis using SPSS statistical data processing tool. The results of the instrument test show that all variables were valid and reliable as a data collection tool. The results of data analysis showed that: 1) Age had no significant effect on the implementation of IMD in post sectio caesarea patients (p = 0.769) because the indication for delivery by sectio caesarea was not carried out in patients with high risk age, but also in productive age. 2) Education had no significant effect on the implementation of IMD in post sectio caesarea patients (p = 0.284) Because knowledge about the importance of early breastfeeding initiation and how to do it is not obtained during formal education but from non-formal education and other educational media, so that other educational media are needed in order to support the implementation of IMD, especially in post sectio cesarea patients. Keywords: Early Initiation Breastfeeding, Education, Sectio Caesarea, Age
Hubungan Intake Protein dengan Status Gizi pada Remaja Puteri
Authors: IIslaamy Talitha Zulis , Endah Yani Ristya Widi , Ningtyias Farida Wahyu
Published: October 2021

At the age of teenagers, students are more concerned with physical appearance. Adolescent girls are a group that is vulnerable to nutritional problems. Poor food intake is a common cause of nutritional problems in adolescents. A balance between the nutrients that enter is needed for optimal health. The data used in this study is a cross sectional design which aims to determine the relationship between protein intake and nutritional status in adolescent girls. Data collection on protein intake variables used a 24-hour food recall form. Data were collected on nutritional status variables using weight measurement with analytical digital scales and height measurements using microtoa. The sample used was 40 female students at MA Mambaul Khoiriyatil Islamiyah. The statistical test used is the Chi Square test. The percentage of respondents with less protein intake is 90%. The conclusion of this study is that there is a significant relationship between protein intake and nutritional status with a p value of 0.035 (<0.05). Keywords: Protein Intake, Nutritional Status, Adolescent Girls
Studi Sanitasi RSU “ Dr. Koesnadi ” Kabupaten Bondowoso
Authors: Ahmadi,S.KM Haris , Ma’rufi. S.KM., M.Kes. Dr. Isa
Published: October 2021

The quality of the Hospital Environment (RS) that is good in terms of physical, biological, chemical, and social will make it a place of health services that can guarantee the maintenance and improvement of the health status of the community. Hospitals are places where there is close contact between humans (visitors, patients, and the community) with the surrounding environment, then the hospital must comply with the sanitation quality standards that have been regulated in the applicable law. Hospital health worthiness is carried out to prevent things that can cause problems in decreasing the quality of sanitation and the quality condition of hospital sanitation facilities, such as waste, clean water media, drinking water, food, air media, infrastructure and building quality as well as vectors/animals carrying disease. resulting in the transmission of disease in the hospital itself. The purpose of the study was to find out the description of the hospital's health-worthy quality which was determined through the achievement of standard environmental quality standards and fulfilled other health requirements at the "Dr. Koesnadi” Hospital Bondowoso. This type of research is classified as descriptive evaluative, namely wanting to obtain an explanation of the sanitary conditions in the hospital. The research subject is “dr. Koesnadi” Hospital Bondowoso and his environment in accordance with the reference to the use of the Hospital Environmental Health Inspection Form (IKL) in accordance with the Minister of Health Regulation No. 007/Menkes/Per/II/2019. The results of the research, in general the results of environmental supervision and inspection are very good (total score of 8,840) but still need improvement on variables, especially air health media on aspects of lighting quality standards and certain spaces, ready food health in the certificate process. Healthy Catering Services Category B and measuring vector density numbers, especially those that are still being carried out so that it will affect vector control activities. Keywords: Hospital, environmental quality, hospital category
Epidemiological survey of oral lesions diagnosed at a stomatology service
Authors: Arruda Etienny da Silva , Sombra Gesom Avohai Dias , Pereira Juliana Vianna , Domingues José Eduardo Gomes , Alcântara Tânia Cristina Chicre , Conde Nikeila Chacon de Oliveira
Published: October 2021

Objetivo: Determinar a prevalência de alterações de mucosa e lesões bucais diagnosticadas na Faculdade de Odontologia da Universidade Federal do Amazonas, Manaus - Brasil. Materiais e métodos: Estudo transversal, descritivo e retrospectivo, que analisou os prontuários de pacientes maiores de 18 anos atendidos entre 2010 e Foram coletados dados relacionados a presença de alterações de tecido mole, com ênfase em lesões de coloração branca, além de variáveis como idade, sexo, uso de medicações, doenças sistêmicas e hábitos deletérios. Os dados foram submetidos a análise descritiva e apresentados através de médias e desvio padrão por meio de tabelas. Resultados: Foram incluídos 82 prontuários, com prevalência do sexo feminino (60,98%) e média de idade de 43,3 anos. Foram encontradas 307 alterações de mucosa bucal, e dentre estas 27,69% consistiam em lesões de coloração branca. Grânulos de Fordyce (35,37%), linha alba (15,85%) e hiperqueratose focal (9,76%) foram as alterações de coloração branca mais relatadas. Dentre as lesões com potencial de malignização, líquen plano, leucoplasia e queilite actínica estiveram presentes em menos de 5% dos achados, correspondendo a 2,6% das alterações brancas encontradas. Conclusão: Os pacientes atendidos neste serviço de estomatologia possuíram alta prevalência de alterações em mucosa bucal, dentre elas, lesões de coloração branca. Certificado de Apreciação Ética nº 38861314.3.0000.5020.
Morfología dental y cénit gingival en adolescentes en la región Junin
Authors: García Sixto , Torres Adriana , Baltodano Aylín
Published: October 2021

La estética en la odontología ha cobrado mayor importancia, se han desarrollado diversos estudios antropométricos sobre estética, pero éstos se desarrollaron en poblaciones caucásicas. Objetivo: determinar la relación del cénit gingival y la morfología dentaria de las piezas dentales superiores del sector anterior en adolescentes peruanos. Material y Métodos: El estudio fue de tipo descriptivo, correlacional y transversal. La muestra fue de tipo probabilístico por conveniencia, y estuvo conformado por 92 adolescentes en la región Junín, Perú. Cada modelo fue analizado y se registró la morfología dental, la posición del cénit gingival y la distancia del cénit gingival al eje longitudinal de pieza dentaria. Resultados: Se obtuvo que la media de la ubicación del cénit gingival para el incisivo central superior  era 72,8% hacia distal (0,54 mm), en cambio el incisivo lateral  (59,2%) y canino (50,5%) estaban en la misma posición que el eje longitudinal del diente. Con respecto al tipo de forma dental, la forma oval se halló en el 71,2% de los incisivos centrales, en el 67,9% de los incisivos laterales y en el 73,9% de los caninos. Se concluyó que la ubicación del cénit gingival en los incisivos centrales superiores se hallaba hacia distal en relación al eje longitudinal, con una distancia promedio de 0,54 mm, en cambio  en los incisivos laterales y caninos superiores  su  cénit gingival se hallaba en el eje longitudinal del diente. Con respecto a la morfología dentaria la forma oval fue la más predominante. Conclusiones: Existe una migración hacia distal de los cénits gingivales en los incisivos centrales, pero no en los incisivos laterales o caninos superiores.
Aplicación del láser de baja potencia para analgesia de la odinofagia causada para radioterapia de cabeza y coello: Reporte de series de casos clínicos
Authors: Grando Liliane , Mituuti Cláudia , Santos Aira , Ghidini Gabriela , Smiderle Fabiane , Simões Alyne , Lisboa Mariáh
Published: October 2021

Objetivo: Proponer el uso del láser de baja potencia extraoral para el tratamiento de la odinofagia asociada a mucositis hipofaríngea radio inducida. La odinofagia se caracteriza por dolor al tragar, que a menudo requiere cambios en la dieta, lo que impacta directamente en la calidad de vida del paciente. Material y métodos: La investigación fue un estudio observacional descriptivo con reporte de series de casos clínicos. Se realizó aplicación de fotobiomodulación extraoral para tres pacientes con odinofagia asociada a mucositis oral e hipofaríngea. Se utilizó la terapia con láser de baja potencia (Therapy XT DMC®), con λ808nm, 100 mW de potencia y 4J de energía, 40 segundos por punto. Se recopilaron, transcribieron y revisaron cualitativamente los informes de tres pacientes que se sometieron a tratamiento. Los puntos de aplicación del láser se propusieron a partir de un estudio anatómico previo en cadáveres, que buscó identificar la mejor zona de aplicación del láser extraoral en la región cervical para llegar a la hipofaringe. Resultados: Los pacientes informaron una reducción de la odinofagia y una mayor comodidad con el uso de este tratamiento en el trígono carotídeo. Conclusión: El trígono carotídeo resultó ser la mejor región extraoral para la aplicación de láser para llegar a la región hipofaríngea. El uso de láser de baja potencia aplicado en esta región redujo la odinofagia de los pacientes. Se necesitan más estudios para evaluar la capacidad analgésica de este tratamiento.
COVID-19 y su impacto en la odontología
Authors: Curay Camacho Yamilette Tatiana , Koo Benavides Valery , Cubas Rivadeneira Kassandra Guadalupe , Huanca Cárdenas Katherine Rocio , López Ramírez Walter Gabriel , Barturen Heredia Edar Willian , Damián Guevara José David , Ladera Castañeda Marysela Irene
Published: October 2021

El COVID-19 es una nueva enfermedad, este virus ha demostrado en diversos estudios tener un tiempo de incubación aproximado de cinco días. Las áreas sanitarias, incluyendo el área odontológica, se han visto en un panorama de alta vulnerabilidad y exposición, ello ha permitido modificar el rol del cirujano dentista durante esta pandemia, adoptando nuevos lineamientos de bioseguridad para preservar la salud del personal asistencial y pacientes. Es así que los protocolos en el uso de EPP, antisepsia de la cavidad bucal y desinfección se han convertido en pilares de la atención de tratamientos de urgencia y emergencia. El objetivo de la presente revisión de literatura es evidenciar la información recolectada durante la crisis sanitaria y la actualización de protocolos adoptados por los cirujanos dentistas y personal asistencial para dar una atención adecuada durante la pandemia.
Manejo de tejidos periimplantarios con provisionales atornillados en Agenesia bilateral: Reporte de caso
Authors: Guerra Raquel , Bolaños Anthony , Chávez Pablo
Published: October 2021

Una de las alternativas de tratamiento para los casos de agenesia de incisivos laterales en el sector superior es mediante la rehabilitación con implantes dentales. Es importante realizar un adecuado diagnóstico y plan de tratamiento respetando los tiempos biológicos para la regeneración ósea y manejo de tejidos, de tal manera el resultado final cumpla con la estética que involucra el caso. El objetivo del presente trabajo es reportar un caso clínico de un paciente de sexo masculino de 24 años de edad con agenesia bilateral superior de los incisivos laterales, recibió tratamiento de ortodoncia por 6 años, para la fase definitiva del tratamiento rehabilitador involucró la regeneración ósea horizontal de las zonas afectadas con injerto autólogo de mentón, la planificación de la colocación de los implantes y el manejo de tejidos periimplantarios.
Educación Dental Asincrónica “EDA”
Authors: Saravia Miguel , Fukuhara Mary
Published: October 2021

El modelo de aprendizaje asíncrono es una posibilidad que podemos hacer uso y resulta realmente valioso y oportuno, más aún en estos momentos que la manera de aprender y generar aprendizajes significativos han sufrido un cambio radical. Se muestra cómo usando tecnologías disruptivas como el teléfono inteligente y algunos aplicativos que se encuentran de manera gratuita en dichos dispositivos nos ayudan a poder generar y transmitir información valiosa que ayuda de manera significativa al aprendizaje de manera síncrona. Educación dental asíncrona persigue generar un material didáctico de calidad para favorecer el aprendizaje corporativo de los alumnos usando tecnologías propias de la generación milenio.
Jaringan Advokasi Transnasional (GAATW) dalam Penyelesaian Isu Migrasi Pekerja Perempuan dan Perdagangan Manusia di Asia Tenggara
Authors: Kristanti Monica Vira Ajeng
Published: October 2021

Southeast Asia is one of the regions that has a fairly high rate of labor migration, both as a contributor and a recipient country. However, this is not equated with strict regulations and laws. Violations of the rights of migrant workers are common in several countries. Unfortunately, ASEAN as a regional regional organization has not been able to provide targeted advocacy. The Transnational Advocacy Network (TAN) is here to provide recommendations and advocacy to migrant workers across countries. In this article, the transnational advocacy network that will be studied further is the Global Alliance Against Trafficking in Women (GAATW) which has been actively advocating and providing policy recommendations to five countries in Southeast Asia, namely Indonesia, Singapore, Cambodia, the Philippines, and Thailand. The research method used in this study is a qualitative method using secondary data. In this study, we can see how GAATW cooperates with several migrant worker unions in these countries, either by conducting research, advocating for victims, or by publishing publications aimed at the public and the government.
INCREASING TEACHERS' CAPABILITIES IN DISTANCE LEARNING USING THE GOOGLE CLASSROOM APPLICATION THROUGH PERSONAL ASSISTANCE OF TEACHERS IN KEMPONG KALIBAWANG, KULON PROGO DISTRICT, 2020/2021
Authors: Wahyuni Dwi
Published: October 2021

This research is motivated by teachers who are still not ready to face distance learning during the Covid-19 pandemic. To overcome this problem researchers take corrective actions through school action research which aims to improve the ability of teachers and researchers to provide personal assistance using the Google Classroom application program for learning. distance and improve school performance in order to be able to compete in the field of graduation. The research design uses a qualitative design, while the data collection technique uses the method of documentation and observation. The data analysis technique was carried out through a qualitative descriptive model consisting of data reduction, data presentation, and drawing conclusions. The results of this study can be seen from the increase in the results of the ability of the participants in personal assistance and the implementation of activities by resource persons from before the action in cycles I and II. In the pre-cycle of participants who got an average score of 3.52, the percentage was 88.04% with the "Very Good" category, there was 1 person while the average score was 3.12, the percentage was 78.12%, the conversion value reached 3, the next 6 participants got a score of 2, the category "Quite Good". Based on the teacher's ability in the first cycle it reached 74.65% if converted the value obtained 3, with the "Good" category while in the second cycle it reached 87.49%, if the conversion value obtained a value of 4, with the "Very Good" category. Based on the implementation of mentoring by the resource persons in the first cycle, it reached 87.46%, if converted the value obtained 4, with the "Very Satisfactory" category while in the second cycle it reached 91.22% if converted the value obtained 4, with the "Very Satisfactory" category
Improving Teacher Competence in Questions on Google Forms Through In House Training (IHT) in the Era of the COVID-19 Pandemic at Candirejo State Elementary School, Kalibawang, Kulon Progo Regency
Authors: Paryati Paryati
Published: October 2021

The purpose of this study is to improve the ability of teachers in preparing questions on google forms. Building teachers' practical ways of thinking in solving problems related to the preparation of HOTS questions, as well as increasing the professionalism of school principals in organizing In House Training (IHT) and increasing the motivation and competence of school principals during the COVID-19 pandemic. This research method is descriptive qualitative through school action research which further deepens the teacher development process related to writing HOTS questions on the google form. The data of this study are qualitative data, while the research subjects are Candirejo State Elementary School teachers, totaling 8 teachers consisting of 6 classroom teachers and 2 study teachers. The results showed that the teacher's ability to write written test questions was initially only 2 people (20%), after the research was carried out with the first cycle of activities from 2 teachers to 8 teachers (100%), while the research activities at the end the implementation of the second cycle of activities with an average score of 69.00 and an average score of 3.80, while based on presentation it reached 94.91%. As for the stage of the second cycle of meeting 1 the teacher's ability in preparing questions through In House Training (IHT) on Google Form there was an increase of 2.14% and at the second meeting of cycle II it rose to 91.79% in the "Very Good" category. And the average score increased in the second cycle of meeting 2 to 64.25 from 61.38. While the activities of IHT participants at the second meeting of the second cycle reached 22.50, the average value of the second cycle of the second meeting reached 3.75 while the percentage-based score reached 93.75% in the "Very Good" category. So that the research can be ended at the stage of cycle II for the second meeting.
Implementation Of Individual Guidance Through Whatsapp Group To Increase Achievement And Learning Motivation Of Students Of Class VII SMP Negeri 3 Ngaglik Sleman 2020/2021
Authors: Suratmi Suratmi
Published: October 2021

This study aims to increase the learning motivation of seventh-grade students of SMP Negeri 3 Ngaglik Sleman through "WhatsApp Group" in individual guidance. The population in this study was 369 students. The sample in this study was class VII SMP Negeri 3 Ngaglik Sleman totaling 128 which was divided into 3. The research method used in this study was Action research Guidance Counseling with the model developed by Kemmis and Mc. Taggart goes through four stages, namely planning, action, observation, and reflection. The research flow is carried out in two cycles. The results showed that the application of individual guidance through WhatsApp Group to the learning outcomes of Class VII students of SMP Negeri Ngaglik Sleman could increase. The average student evaluation results have exceeded the minimum value for each subject. As for the results after the students carried out mentoring activities for 3 cycles, as many as 5 students were in the very good category, and as many as 25 students were in a good category, and in the sufficient category as many as 2 students. Overall, the development of learning outcomes before being given action (pre-action) and after being given action for 3 cycles increased by 93.75%. Based on the results of the study showed that as much as 85% in the process of applying individual guidance through "WhatsApp group" on learning motivation can be used as an alternative in an effort to improve the process and learning outcomes of students.
PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells
Authors: Tang Wei , Wu Yu , Qi Xin , Yu Rilei , Lu Zhimin , Chen Ao , Fan Xinglong , Li Jing
Published: October 2021

Objective: Glycogen synthase kinase-3β (GSK3β) has been recognized as a suppressor of Wnt/β-catenin signaling, which is critical for the stemness maintenance of breast cancer stem cells. However, the regulatory mechanisms of GSK3β protein expression remain elusive. Methods: Co-immunoprecipitation and mass spectral assays were performed to identify molecules binding to GSK3β, and to characterize the interactions of GSK3β, heat shock protein 90 (Hsp90), and co-chaperones. The role of PGK1 in Hsp90 chaperoning GSK3β was evaluated by constructing 293T cells stably expressing different domains/mutants of Hsp90α, and by performing a series of binding assays with bacterially purified proteins and clinical specimens. The influences of Hsp90 inhibitors on breast cancer stem cell stemness were investigated by Western blot and mammosphere formation assays. Results: We showed that GSK3β was a client protein of Hsp90. Hsp90, which did not directly bind to GSK3β, interacted with phosphoglycerate kinase 1 via its C-terminal domain, thereby facilitating the binding of GSK3β to Hsp90. GSK3β-bound PGK1 interacted with Hsp90 in the “closed” conformation and stabilized GSK3β expression in an Hsp90 activity-dependent manner. The Hsp90 inhibitor, 17-AAG, rather than HDN-1, disrupted the interaction between Hsp90 and PGK1, and reduced GSK3β expression, resulting in significantly reduced inhibition of β-catenin expression, to maintain the stemness of breast cancer stem cells. Conclusions: Our findings identified a novel regulatory mechanism of GSK3β expression involving metabolic enzyme PGK1-coupled Hsp90, and highlighted the potential for more effective cancer treatment by selecting Hsp90 inhibitors that do not affect PGK1-regulated GSK3β expression.
SHP-1 acts as a tumor suppressor by interacting with EGFR and predicts the prognosis of human breast cancer
Authors: Geng Qian , Xian Ruiting , Yu Yinjue , Chen Fengsheng , Li Rong
Published: October 2021

Objective: The aims of this study were to examine the prognostic value of SHP-1 in breast cancer, its roles in the regulation of breast cancer cell growth and metastasis, and the underlying mechanisms. Methods: Tumor specimens from 160 patients with breast cancer and 160 noncancerous tissues were used to examine the expression of SHP-1 and to analyze its association with overall survival through Kaplan–Meier and multivariate Cox regression analyses. RNA sequencing data and the expression and clinical importance of SHP-1 in breast cancer were evaluated with data from The Cancer Genome Atlas. In vitro and in vivo assays were performed to elucidate the effects of SHP-1 on breast cancer cell proliferation and invasion. Confocal immunofluorescence and GST pulldown assays were used to demonstrate the interaction between SHP-1 and epidermal growth factor receptor, as well as its downstream pathways. Immunohistochemistry and The Cancer Genome Atlas database were used to investigate the clinical association between SHP-1 and EGFR in human breast cancer. Results: SHP-1 expression was associated with better survival in patients with breast cancer, whereas SHP-1 expression was negatively correlated with EGFR in human breast cancer. Ectopic SHP-1 expression significantly suppressed breast cancer cell proliferation, migration, and invasion. SHP-1 knockdown induced a more invasive phenotype and accelerated cell growth. Mechanistically, EGFR, a protein directly interacting with SHP-1, mediates the SHP-1-induced inactivation of Ras/Erk/GSK3β signaling and its downstream effectors. Conclusions: SHP-1 is an important prognostic biomarker in patients with breast cancer, and the SHP-1-EGFR axis is a promising target for treatment.
Improved diagnosis of thyroid cancer aided with deep learning applied to sonographic text reports: a retrospective, multi-cohort, diagnostic study
Authors: Zhang Qiang , Zhang Sheng , Li Jianxin , Pan Yi , Zhao Jing , Feng Yixing , Zhao Yanhui , Wang Xiaoqing , Zheng Zhiming , Yang Xiangming , Liu Lixia , Qin Chunxin , Zhao Ke , Liu Xiaonan , Li Caixia , Zhang Liuyang , Yang Chunrui , Zhuo Na , Zhang Hong , Liu Jie , Gao Jinglei , Di Xiaoling , Meng Fanbo , Ji Wei , Yang Meng , Xin Xiaojie , Wei Xi , Jin Rui , Zhang Lun , Wang Xudong , Song Fengju , Zheng Xiangqian , Gao Ming , Chen Kexin , Li Xiangchun
Published: October 2021

Objective: Large volume radiological text data have been accumulated since the incorporation of electronic health record (EHR) systems in clinical practice. We aimed to determine whether deep natural language processing algorithms could aid radiologists in improving thyroid cancer diagnosis. Methods: Sonographic EHR data were obtained from the EHR database. Pathological reports were used as the gold standard for diagnosing thyroid cancer. We developed thyroid cancer diagnosis based on natural language processing (THCaDxNLP) to interpret unstructured sonographic text reports for thyroid cancer diagnosis. We used the area under the receiver operating characteristic curve (AUROC) as the primary metric to measure the performance of the THCaDxNLP. We compared the performance of thyroid ultrasound radiologists aided with THCaDxNLP vs. those without THCaDxNLP using 5 independent test sets. Results: We obtained a total number of 788,129 sonographic radiological reports. The number of thyroid sonographic data points was 132,277, 18,400 of which were thyroid cancer patients. Among the 5 test sets, the numbers of patients per set were 439, 186, 82, 343, and 171. THCaDxNLP achieved high performance in identifying thyroid cancer patients (the AUROC ranged from 0.857–0.932). Thyroid ultrasound radiologists aided with THCaDxNLP achieved significantly higher performances than those without THCaDxNLP in terms of accuracy (93.8% vs. 87.2%; one-sided t-test, adjusted P = 0.003), precision (92.5% vs. 86.0%; P = 0.018), and F1 metric (94.2% vs. 86.4%; P = 0.007). Conclusions: THCaDxNLP achieved a high AUROC for the identification of thyroid cancer, and improved the accuracy, sensitivity, and precision of thyroid ultrasound radiologists. This warrants further investigation of THCaDxNLP in prospective clinical trials.
The mutation landscape of multiple cancer predisposition genes in Chinese familial/hereditary breast cancer families
Authors:   Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin&, Dong Li ,   #x2019,   s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin 300060, China
Published: October 2021

Objective: Approximately 5%–10% of breast cancer (BC) patients display familial traits that are genetically inherited among the members of a family. The purpose of this study was to profile the germline mutations in 43 genes with different penetration rates and their correlations with phenotypic traits in Chinese familial BC families. Methods: Ion Torrent S5™-based next generation sequencing was conducted on 116 subjects from 27 Chinese familial BC families. Results: Eighty-one germline mutations in 27 BC predisposition genes were identified in 82.8% (96/116) of the cases. Among these, 80.8% of the mutated genes were related to DNA damage repair. Fourteen possible disease-causing variants were identified in 13 of 27 BC families. Only 25.9% (7/27) of the BC families exhibited hereditary deficiency in BRCA1/2 genes, while 22.2% of the BC families exhibited defects in non-BRCA genes. In all, 41.7% (40/96) of the mutation carriers had BRCA mutations, 88.5% (85/96) had non-BRCA mutations, and 30.2% (29/96) had both BRCA and non-BRCA mutations. The BC patients with BRCA mutations had a higher risk of axillary lymph node metastases than those without mutations (P < 0.05). However, the BC patients with non-BRCA mutations frequently had a higher occurrence of benign breast diseases than those without mutations (P < 0.05). Conclusions: In addition to BRCA1/2, genetic variants in non-BRCA DNA repair genes might play significant roles in the development of familial/hereditary BC. Therefore, profiling of multiple BC predisposition genes should be more valuable for screening potential pathogenic germline mutations in Chinese familial/hereditary BC.
The active surveillance management approach for patients with low risk papillary thyroid microcarcinomas: is China ready?
Authors: Liu Wen , Yan Xuejing , Cheng Ruochuan
Published: October 2021

Due to exponential increases in incidences, low risk papillary thyroid microcarcinoma (PTMC) has become a clinical and social issue in recent years. An active surveillance (AS) management approach is an alternative to immediate surgery for patients with low risk PTMC. With decreased doubts about the safety and validity due to evidence from a large number of studies, the AS approach has become increasingly popular worldwide. However, Chinese thyroid surgeons still lag behind other countries in their knowledge of clinical practices and research related to AS. To promote the implementation of AS in China, thyroid surgeons should understand the implications, advantages, and disadvantages of management approaches for AS, and should also consider the willingness of Chinese patients, the impact on the medical billing system, and the enthusiasm of doctors. Thus, a management approach for AS based on the Chinese population should be developed to reduce the risk of disease progression and enhance patient adherence. Herein, we summarize the recent research achievements and deficiencies in AS approaches, and describe the initial experiences regarding AS in the Chinese population, in order to assist Chinese thyroid surgeons in preparing for AS management in the era of PTMC precision medicine.
Function Representation for Basic Processes Modeling in 3D Bioprinting
Authors: Pakhomova Katherine Alex , Pasko Alexander Alexandrovich , Akhatov Iskander Shaukatovich
Published: October 2021

We propose a non-invasive approach to control the quality of spheroids and their fusion into a complex bioconstruct. The proposed method is based on the union of the nutrient concentration change calculated using Fick's law and the "reaction-diffusion" equations, taking into account absorption coefficient with specifying the exact fusion geometry using implicit Function Repre-sentation (FRep) functions. The proposed approach allows us to analyze the viability of cells within the spheroid, predict the fusion of spheroids, and accurately model complex heteroge-neous biostructures as a future task for our research. These results will significantly accelerate the development of such a promising field of additive biotechnologies as 3D bioprinting.
The Neurobiology of Autism Spectrum Disorder As It Relates to Twice Exceptionality
Authors: Sharkey Rachel , Nickl-Jockschat Thomas
Published: October 2021

There is a long-standing association between exceptional cognitive abilities, of various sorts, and neuropsychiatric illness, but it has historically largely been investigated in an exploratory and non-systematic way. One group in which this association has been investigated with more rigor is in subjects who have been identified as twice exceptional; an educational term describing subjects who are both gifted and diagnosed with a neuropsychiatric disability. This term covers multiple conditions, but is of specific interest in particular in the study of autism spectrum disorder. Recent findings have led to the development of a hypothesis that a certain degree of the neurobiology associated with autism might even be advantageous for individuals and could lead to high giftedness, while becoming disadvantageous, once a certain threshold is surpassed. In this model, the same neurobiological mechanisms confer an increasing advantage up to a certain threshold, but become pathological past that point. Twice-exceptional individuals would be exactly at the inflection point, being highly gifted, but also symptomatic at the same time. Here, we review how existing neuroimaging literature on autism spectrum disorder can inform research on twice exceptionality specifically. We propose to study key neural networks with a robust implication in ASD to identify the neurobiology underlying twice-exceptionality. A better understanding of the neural mechanisms of twice exceptionality should help to better understand resilience and vulnerability to neurodevelopmental disorders and tofurther support affected individuals.
Emotional exhaustion in Peruvian university students during the COVID-19 pandemic
Authors: Araoz Edwin Gustavo Estrada
Published: October 2021

The COVID 19 pandemic has caused the teaching-learning modality to go from being face-to-face to being virtual, which has forced students to adapt to this new scenario, however, despite the fact that this modality has favorable aspects, it also it has had implications in the socio-emotional aspect. Therefore, the present research aimed to describe the emotional exhaustion in Peruvian students from a private university during the COVID-19 pandemic. The approach was quantitative, the design was non-experimental, and the type was descriptive, transectional. The sample consisted of 265 students, to whom the Emotional Tiredness Scale was applied, an instrument with required levels of validity and reliability. The results found indicate that the students presented high levels of emotional exhaustion (39.4%) and it was determined that some sociodemographic variables such as sex and age were significantly associated with this condition (p<0.05). It was concluded that it is necessary for the University's Psychology area to detect students with high levels of emotional exhaustion in a timely manner so that they receive treatment and can improve their academic performance and quality of life. On the other hand, students should be encouraged to develop coping strategies for stressful situations, typical of academic life and the context of pandemic.
CONSUMER WORTH AS A SYSTEM
Authors: VASIUCHONAK L.
Published: October 2021

Consumer worth is a system of relations between people and things regarding the correspondence of endowing things with certain functional properties (production) to their socially determined extraction (consumption). Consumer worth in a post-industrial society serves as an effective tool for determining the behavior of economic entities - people and their organizations - in the coordinates of the commodity economy, their orientation on the production of value on the principles of abstract equivalence, combinatorics and virtual calculus. Creation of new functional properties of things as a consumer values, their integration into society and building society for them pushes the boundaries of the commodity form of economy.
PROPERTY AS A POLITICAL AND ECONOMIC CATEGORY IN THE 21ST CENTURY
Authors: SOLODOVNIKOV S.
Published: October 2021

The article systematically considers traditional and modern approaches to the definition
of property as an economic phenomenon. The general and special in relation to property in the 21st century are shown. In particular, the author notes an increase in the value of ownership of functions and “dispersed” forms of ownership in the network economy, as well as a wide range of objects of property relations, which includes the entire set of economic goods — material means of production, the natural environment, and consumer values, information and social conditions of production, production and social abilities of individuals and the production and socio-economic functions themselves, information and knowledge. The definition of property as a political and economic category is given.