bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Dienogest Alone or in Combination with Ethinylestradiol on the Quality of Life of Women with Endometriosis: A Prospective Cohort Study
Authors: Canbay Mujde , Salman Suleyman
Published: December 2023

OBJECTIVE: We aim to compare the effectiveness of oral contraceptives and dienogest, primarily by considering the quality of life scale. We also aim to compare the Cancer Antigen-125 and Anti-mullerian Hormone values.
STUDY DESIGN: Gynecological examination findings evaluated based on ESHRE and ASRM Guideline criteria are compatible with endometriosis, or a previous surgery pathology result is consistent with endometriosis, and patients whose imaging report was compatible with endometriosis were selected. Among the patients who were recommended medical treatment, patients selected as Dionegest 2mg+Ethinylestradiol 0.03 mg (Dienelle) treatment were considered Group 1, and patients deemed suitable for treatment with treatment 2mg Dionegest (Visanne) were considered Group 2. Pre-treatment Cancer Antigen-125/Anti-mullerian Hormone values and SF-36 were recorded.
RESULTS: There was no significant difference between drug groups in terms of education status, body mass index, family history, smoking, alcohol consumption, age, age at menarche, menstruation pattern, duration of menstruation, infertility, gestational status, job loss due to pain complaints, operation, and MRI findings (p>0.05). There was no significant difference between the drug groups regarding the quality of life before and after treatment (p>0.05). There was no significant difference between drug groups regarding endometrioma size, Cancer Antigen-125, and anti-mullerian hormone findings (p>0.05).
CONCLUSION: Evaluating our data, the efficacy and success of the two treatment protocols were the same. It seems more logical to prefer cost-effective oral contraceptive treatments with a low side-effect profile than high-cost Dionegest. Following the guidelines accepted step therapy in treating mild or moderate endometriosis, cyclic oral contraceptives may be recommended as first-line therapy.
Breast Cancer-related Lymphedema: Recent Updates on Clinical Efficacy of
Therapies and Bioengineering Approaches for a Personalized Therapy
Authors: Zhang Xinliang , Beeraka Narasimha M. , Sinelnikov Mikhail Y. , Glazachev Oleg S. , Ternovoy Konstantin S. , Lu Pengwei , Isaeva Aida , Cao Yu , Zhang Jin , Nezhad Arshia Bakhtiari , Plotnikova Maria , Chen Kuo
Published: December 2023

Background:

Post-mastectomy lymphedema is a chronic progressive disease characterized by a significant
reduction in quality of life and a range of complications.

Aim:

To this date, no single treatment method provides pathological correction of the mechanisms associated
with tissue reorganization observed in later-stage breast cancer-related lymphedema (BCRL).

Methods:

To define a personalized approach to the management of patients with iatrogenic lymphedema, we
performed a systematic review of literature without a comprehensive meta-analysis to outline existing molecular-
genetic patterns, overview current treatment methods and their efficacy, and highlight the specific tissue-associated
changes in BCRL conditions and other bio-engineering approaches to develop personalized therapy.

Results:

Our results show that several tissue-specific and pathological molecular markers may be found, yet
current research does not aim to define them.

Conclusion:

As such, currently, a strong foundation for further research into molecular-genetic changes in
lymphedema tissue exists, and further research should focus on finding specific targets for personalized treatment
through bio-engineering approaches.
Privileged Scaffolds in Drug Discovery against Human Epidermal Growth Factor
Receptor 2 for Cancer Treatment
Authors: Peerzada Mudasir Nabi , Hamdy Rania , Rizvi Masood Ahmad , Verma Saurabh
Published: December 2023

HER2 is the membrane receptor tyrosine kinase showing overexpression in several human malignancies,
particularly breast cancer. HER2 overexpression causes the activation of Ras- MAPK and PI3K/Akt/
NF-κB cellular signal transduction pathways that lead to cancer development and progression. HER2 is, therefore,
presumed as one of the key targets for the development of tumor-specific therapies. Several preclinical
have been developed that function by inhibiting the HER2 tyrosine kinase activity through the prevention of
the dimerization process. Most HER2 inhibitors act as ATP competitors and prevent the process of phosphorylation,
and abort the cell cycle progression and proliferation. In this review, the clinical drug candidates and
potent pre-clinical newly developed molecules are described, and the core chemical scaffolds typically
responsible for anti-HER2 activity are deciphered. In addition, the monoclonal antibodies that are either used
in monotherapy or in combination therapy against HER2-positive cancer are briefly described. The identified
key moieties in this study could result in the discovery of more effective HER2-targeted anticancer drug molecules
and circumvent the development of resistance by HER2-specific chemotherapeutics in the future.
Efficient Synthesis and Characterization of 6-substituted-N-p-tolyl-imidazo[1,2-
a]pyridine-8-carboxamide: A Promising Scaffold for Drug Development
Authors: Bhatt Keval , Patel Dhara , Rathod Mrudangsinh , Patel Ashish , Shah Drashti
Published: December 2023

Imidazo[1,2-a]pyridine is a highly significant fused bicyclic heterocycle widely
utilized in medicinal chemistry, and it holds a prominent position as a "drug prejudice"
framework because of its extensive applications. Numerous approaches have been documented
for the synthesis of imidazo[1,2-a]pyridines, with a particular focus on functionalizing
these compounds. In this research, we have presented an effective multi-step synthesis method
for producing imidazo[1,2-a]pyridines, achieving impressive yields ranging from 93% to
97%. The synthesized compounds were subjected to thorough characterization using various
spectral analysis techniques, including FTIR, 1H NMR, 13C NMR, mass spectrometry, and
elemental analysis. Overall, this synthetic strategy possesses desirable features for the synthesis
of imidazo[1,2-a]pyridines and their derivatives, including high product purity, accessible
starting materials, broad substrate scope, scalability, and transformability. These characteristics make it a promising
approach for further development and potential application in the synthesis of valuable therapeutic compounds.
Comparative Pharmacokinetics of Intravenous Enrofloxacin in One- Six- And
Twelve-Month-Old Sheep
Authors: Coskun Devran , Corum Orhan , Durna Corum Duygu , Uney Kamil
Published: December 2023

Background:

Enrofloxacin (ENR) is a fluoroquinolone antibiotic approved for use in sheep of all
ages. The body composition and metabolic capability change with age. These changes may alter the pharmacokinetics
of drugs and thus their effect. Therefore, the pharmacokinetics of drugs need to be established in target-
age animals

Objective:

To determine the pharmacokinetics of ENR and its active metabolite, ciprofloxacin (CIP), following
a single intravenous administration of ENR at a dose of 10 mg/kg in different ages of sheep.

Methods:

The study was carried out in the one-, six- and twelve-month age period of the sheep. A single dose
of 10 mg/kg ENR was administered intravenously through the jugular vein to sheep in all age periods. ENR
and CIP plasma concentrations were determined using HPLC–UV and analyzed using a non-compartmental
method.

Results:

ENR was detected in the plasma until 36 h in one-month-old and up to 24 h in other ages. CIP was detected
in the plasma up to 24 h in all age groups. The t1/2ʎz and Vdss were significantly higher in one-month-old
sheep than in six and twelve-months old sheep. There was no difference in ClT and AUC values in different
age groups. AUC0-∞CIP/AUC0-∞ENR ratios were higher in one-month-old than in six- and twelve-months sheep.

Conclusion:

The most important pharmacokinetic changes associated with aging in sheep are decreased Vdss
and t1/2ʎz of ENR and the low ratio metabolizing of ENR to CIP. Pharmacokinetic/pharmacodynamic data
showed that ENR after IV administration of 10 mg/kg dose provided the optimal AUC0–24/MIC90 ratios for E.
coli, P. multocida and Mycoplasma spp. (>125) with MIC of 0.37 μg/mL and for S. aureus (>30) with MIC of
0.5 μg/mL in all ages of sheep.
Does the Grape Products Intake has an Effect on Body Weight in Adults:
A Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Goudarzi Mohammad Ali , Sohrabi Zahra , Hashempur Mohammad Hashem , Nosratabadi Saeed , Namkhah Zahra , Clark Cain C.T. , Haghighat Neda
Published: December 2023

Introduction::

There is a growing interest in the considerable benefits of grape products
intake, as some studies have indicated that they may improve cardiometabolic risk factors. However,
the widespread impact of grape products on the anthropometric indices is not fully resolved.

Method::

The purpose of this systematic review and meta-analysis was to examine the effects of
grape products intake on anthropometric indices in adults. Randomized controlled trials (RCT) examining
the effects of grape products intake on anthropometric indices, published up to December
2021, were identified through PubMed, SCOPUS, and ISI Web of Science databases. 30 studies
with 35 effect sizes, including 1284 participants (708 cases and 576 controls), were included and
analyzed using a random-effects model to calculate weighted mean differences (WMDs) with
95% confidence interval (CI).

Result::

The outcomes have revealed grape products intake to significantly decrease body weight
(p = 0.001) and body mass index (p = 0.004) in obese participants, and also, a greater effect was
observed when grape seed extract was used.

Conclusion::

Our study suggests that grape products intake may help to decrease body weight in
obese participants. Future large RCTs with longer duration and obese populations are needed to expand
our findings.
Predicting Futile Recanalization in Acute Ischemic Stroke Patients
Undergoing Endovascular Thrombectomy: The Role of White Blood Cell
Count to Mean Platelet Volume Ratio
Authors: Yu Wantong , Jia Milan , Guo Wenting , Xu Jiali , Ren Changhong , li Sijie , Zhao Wenbo , Chen Jian , Duan Jiangang , Ma Qingfeng , Song Haiqing , Ji Xunming
Published: December 2023

Background:

Approximately half of AIS patients have an unfavorable outcome even
after complete reperfusion. White blood cell (WBC) count to mean platelet volume (MPV) ratio
(WMR) may be a promising predictive factor for futile recanalization. This study aimed to determine
the predictive value of WMR in identifying individuals at higher risk of futile recanalization.

Methods:

In this retrospective cohort study, 296 patients who achieved complete reperfusion
after endovascular treatment (EVT) were included in the analysis. WBC count and MPV were
collected at admission. Multivariable logistic regression was used to examine the independent
association of the WMR with functional outcomes at three months. Net reclassification improvement
(NRI) and integrated discrimination improvement (IDI) analyses were used to compare
the accuracy of WMR for predicting futile recanalization.

Results:

The adjusted odds ratios for the fourth quartile of WMR were 3.142 (95% CI 1.405-
7.027, P = 0.005) for unfavorable outcomes at 3 months in comparison with the first quartile.
The inclusion of WMR in the traditional model enabled a more accurate prediction of unfavorable
outcomes (NRI 0.250, P = 0.031; IDI 0.022, P = 0.017).

Conclusion:

Elevated WMR at admission was independently associated with futile recanalization
among AIS patients who received EVT and might be useful in identifying futile recanalization.
The Effect of Silencing MiR-4270 on Apoptosis in HCC Cell Line
Authors: Gholamia Hanieh , Akrami Hassan , Sassan Hosseinali , Erfani Nasrollah , Fattahi Mohammad Reza , Heidari Mojdeh
Published: December 2023

Background::

Hepatocellular carcinoma (HCC) is the most common type of cancer.
Although HCC treatment has greatly improved over the past few decades, patient survival rates
are still very low. Therefore, it is essential to find new treatments for HCC. Apoptosis has been
shown to be the most effective in disrupting cancer growth. Improper functioning of proteins in
apoptosis can lead to cancer growth. MicroRNAs (miRNAs) are key regulators in the development
and progression of HCC.

Objective::

Irregular expression of miRNAs involved in apoptosis signaling can lead to tumorigenesis.
Therefore, we investigated the effect of the hsa-miR-4270 inhibitor on cell proliferation
and apoptosis.

Methods::

HepG2 cells were cultured at 37°C and 95% air. Transfection of HepG2 cells was
performed by miR-4270 inhibitor and lipofectamine 2000. Cell proliferation of HepG2 cells was
determined with MTT assay and different concentrations of miR-4270 specific inhibitors. DNA
laddering assay was performed to evaluate the induction of apoptosis. Finally, the transcription
level of genes involved in apoptosis, including BAX, BCL2, Caspase3, and p53, was measured
by real-time RT-PCR.

Results::

The results of MTT and DNA laddering assays showed that the miR-4270 inhibitor
declined cell proliferation and induced apoptosis in HepG2 cells. Also, the results of quantitative
real-time RT-PCR indicated an upregulation of transcription of BAX, p53 and Caspase3 genes
and a decline in expression of BCL2 gene.

Conclusion::

Taken together, we found hsa-miR-4270 inhibitor decreased cell proliferation and
induced apoptosis in the HepG2 cell line, which can be used as a new therapeutic strategy for
HCC patients.
Relación de la productividad en fincas bananeras con el perfil de los racimos en Urabá-Antioquia
Authors: Bernal-Monterrosa Miguel Angel , Delgado-Bejarano Laura , Causil Pastrana Ever José , Algarín Guerra Luís Javier
Published: December 2023

The development and production of bananas are influenced by spatio-temporal edaphoclimatic conditions, which explains in a certain way the heterogeneous response that occurs on the farms, highlighting the need to generate information regarding the morphological characteristics of fruit for taking corrective actions that entail to increased productivity. The objective of this research was to carry out an analysis of production, taking into account the quantifiable variables through bunches profiling. 98,956 bunches recorded in a period of 108 weeks between 2021 and 2022 were analyzed in ten farms of two banana groups in Urabá-Antioquia, in the municipalities of Turbo, Apartadó and Carepa. Variables such as: cluster age, cluster weight, number of hands, basal-apical calibration, basal-apical length, removal of fingers and hands in the field. The R 4.2.1 software was used, with which a Spearman correlation, analysis of variance (ANOVA) was obtained and for comparison of means, a Kruskal post-hoc was done. Statistical differences were identified (p-value<2.2e-16) and the highest correlations were between age-weight (0.24), age-basal calibration (0.23) and number of hands-weight (0.45). These results indicate that harvest profiling is a practical and agile method that allows quantifying morphological variables of the bunches, making yield projections and adjusting agronomic management depending on the specifications of the marketer.
BERT-Based Neural Network for Inpatient Fall Detection From Electronic Medical Records: Retrospective Cohort Study
Authors: Cheligeer Cheligeer , Wu Guosong , Lee Seungwon , Pan Jie , Southern Danielle A , Martin Elliot A , Sapiro Natalie , Eastwood Cathy A , Quan Hude , Xu Yuan
Published: December 2023

Background

Inpatient falls are a substantial concern for health care providers and are associated with negative outcomes for patients. Automated detection of falls using machine learning (ML) algorithms may aid in improving patient safety and reducing the occurrence of falls.

Objective

This study aims to develop and evaluate an ML algorithm for inpatient fall detection using multidisciplinary progress record notes and a pretrained Bidirectional Encoder Representation from Transformers (BERT) language model.

Methods

A cohort of 4323 adult patients admitted to 3 acute care hospitals in Calgary, Alberta, Canada from 2016 to 2021 were randomly sampled. Trained reviewers determined falls from patient charts, which were linked to electronic medical records and administrative data. The BERT-based language model was pretrained on clinical notes, and a fall detection algorithm was developed based on a neural network binary classification architecture.

Results

To address various use scenarios, we developed 3 different Alberta hospital notes-specific BERT models: a high sensitivity model (sensitivity 97.7, IQR 87.7-99.9), a high positive predictive value model (positive predictive value 85.7, IQR 57.2-98.2), and the high F1-score model (F1=64.4). Our proposed method outperformed 3 classical ML algorithms and an International Classification of Diseases code–based algorithm for fall detection, showing its potential for improved performance in diverse clinical settings.

Conclusions

The developed algorithm provides an automated and accurate method for inpatient fall detection using multidisciplinary progress record notes and a pretrained BERT language model. This method could be implemented in clinical practice to improve patient safety and reduce the occurrence of falls in hospitals.
Manifestation of female subjugation and sexual exploitation: An analytical study of Maya Angelou’s I Know Why the Caged Bird Sings
Authors: Tripathi Rsvika , Sharma Dr. Geeta
Published: December 2023

The study underscores the challenges faced by racial subalterns in America, with Maya Angelou's renowned autobiography, I Know Why the Caged Bird Sings, providing detailed insights into the hardships endured by this community. Born during the Jim Crow Laws Era, Maya faced severe racial segregation, particularly evident in the racial animosities prevailing in Stamps, Arkansas, between Americans and subalterns (Blacks). Maya became a victim of patriarchal oppression, a consequence of her status as a subaltern and African American in a society predominantly controlled by men. The subjugation experienced by subaltern women restricted their freedom to pursue their dreams, subjecting them to domination by their counterparts. The shared inferior and marginalized status of African Americans in society serves as a thematic backdrop. Maya, however, transcended these challenges, breaking the metaphorical glass ceiling to become the voice of her racial subaltern community. Notably, she achieved the historic milestone of becoming the first subaltern woman to ascend to a position of prominence.
Survey Research on Physical Education Teaching Satisfaction—Taking Adamson University as an Example
Authors: Cui Yangyang
Published: December 2023

In order to improve the quality of physical education teaching in colleges and universities and the love of sports among college students, a survey and research on the satisfaction of physical education teaching among college students was conducted. Methods such as literature method, questionnaire survey method, interview method and mathematical statistics method were used to conduct questionnaire surveys and interviews with college students. Research results show that college students' satisfaction with physical education teaching is affected by many factors, including teaching content, teaching methods, teacher quality and teaching environment. Suggestions for improving physical education teaching in colleges and universities include optimizing the content of physical education and increasing the diversity and practicality of physical education content; secondly, flexibly using physical education teaching methods to increase the interactivity and participation of physical education; and thirdly, continuously improving physical education. Teacher quality specifically requires strengthening the professional training of physical education teachers and optimizing the age structure of physical education teachers; finally, improving the physical education teaching environment and providing safe and comfortable physical education teaching venues, facilities and sports equipment.
Case Study: Factors Affecting the Behavior of School Students in the Age of Pre-Adolescence
Authors: Jeevarathinam N. , Shanmugam Kalaiyarasi , Saravanan B.
Published: December 2023

Using multilevel modeling, this study sought to understand the factors affecting the behaviour of school students at the age of pre-adolescence. The study included 1977 pre-adolescents (1031 boys, 946 girls) from middle schools (Grades 4–7) in suburban areas of the United States from the Department of Children and Family (DCF) 2014 National Child and Youth Panel Survey database. The individual and environmental effects of significant factors affecting pre-adolescent behavior were studied using multilevel models. Among the characteristics linked to emotional-behavioral difficulties were BMI, study tendency, and socioeconomic status. Emotional-behavioral disorders were linked to connections with teachers, according to more studies. The school, family, friends, community, and media all negatively affect students' conduct. As a result, similar educational institutions should teach students social and emotional skills. This may help reduce student disruption. Individual and environmental factors influence pre-adolescents' emotional-behavioral issues. Preventing emotional-behavioral issues require addressing both the environment in which preadolescents live and their unique traits.
CareerConnector
Authors: Yadav Abhishek
Published: December 2023

Abstract: Career Connector is an innovative online platform designed to facilitate efficient job searching and recruitment processes, connecting job seekers with potential employers. Powered by a robust technology stack, with .Net serving as the backend language, CareerConnector offers a seamless user experience for both job seekers and employers. Key functionalities encompass user registration and profile creation, advanced job search and filtering, streamlined job posting and application processes, user notifications, and an array of administrative tools for platform management. Additionally, the system incorporates advanced features such as resume upload and parsing, applicant tracking, machine learning-driven job recommendations, and user feedback and review systems. CareerConnector places paramount importance on data privacy and security, adhering to pertinent data protection laws while implementing stringent encryption measures. Scalability and performance optimization are integral to ensuring a smooth and responsive user experience, even as the platform expands. By embracing. Net as the backend language, CareerConnector benefits from its reputation for reliability, scalability, and a wealth of community support. .Net , including React.js, provide the essential infrastructure for handling HTTP requests and database interactions. The ultimate aim of CareerConnector is to create a dynamic, user-centric job portal that effectively bridges the gap between job seekers and employers. By streamlining the job search and recruitment process, it contributes to a more efficient and vibrant
Characterization of Soil Physicochemical Properties in Boda Area, Batauli Block, District Surguja, Chhattisgarh
Authors: Dewangan Shailesh Kumar
Published: December 2023

Abstract: The physico-chemical properties of soil play an important role in determining its fertility, productivity and overall suitability for various land uses. The objective of this study is to characterize the physicochemical properties of soil in Boda area, Batauli block, district Surguja, Chhattisgarh. A systematic sampling approach was employed, and soil samples were collected from various locations within the study area. The collected samples were analyzed for various physicochemical parameters including soil pH, electrical conductivity (EC), organic matter content, texture, nutrient content (nitrogen, phosphorus, and potassium), and heavy metal concentrations. The results showed that the soil in the Boda area had a slightly acidic to neutral pH range, with variations observed at different locations. Electrical conductivity values indicated moderate salinity levels, which may have an impact on soil fertility and plant growth. The amount of organic matter varied across the study area, with some locations exhibiting greater amounts of organic matter than others. Overall, the findings of this study provide valuable insights into the physicochemical properties of soils in Boda area, Batauli block, district Surguja, Chhattisgarh. These findings can serve as a baseline for future land management and agricultural practices in the region, aiding sustainable land use planning and soil fertility improvement strategies.
Mental Health Effects of Social Media on Adolescents
Authors: Tiwari Rohit
Published: December 2023

Abstract: The rise of social media platforms has revolutionized the way adolescents interact and communicate. This paper aims to delve into the intricate relationship between social media usage and the mental health of adolescents. With the pervasive integration of social media in their lives, this study seeks to examine the potential implications on their mental well-being, specifically focusing on anxiety, depression, and self-esteem. The research methodology involves a comprehensive literature review of academic articles, studies, and surveys conducted on the subject matter. Analysis of various empirical studies allows for the identification of patterns, trends, and correlations between social media engagement and mental health outcomes among adolescents. Several key findings emerge from the collected data. Firstly, there exists a discernible association between heightened social media use and increased levels of anxiety and depression among adolescents. The constant exposure to idealized images, cyberbullying, and the pressure to conform to societal standards significantly contribute to elevated stress levels and emotional distress. Moreover, the impact on self-esteem warrants attention, as comparisons to curated online personas often lead to feelings of inadequacy and decreased self-worth. The phenomenon of 'social comparison' perpetuated by social media exacerbates these negative feelings, creating a distorted perception of reality. However, amidst these adverse effects, the research also highlights potential avenues for positive engagement. Moderation, responsible usage, and awareness campaigns aimed at fostering digital literacy and resilience strategies emerge as potential mitigating factors.
Chatbot for MindTech Digital Solutions
Authors: N S Ms. Shilpa
Published: December 2023

Abstract: Technological advancements have opened the door for businesses to automate customer service through artificial intelligence (AI) chatbots. While these digital assistants offer a range of potential benefits, interactions with them can often feel robotic and sterile. AI chatbots have undoubtedly revolutionized customer service. They offer 24/7 availability, handle repetitive tasks with lightning speed, and can access vast stores of information. However, their purely functional nature can leave customers feeling disconnected and yearning for a more personal touch. This study explores the concept of using humour in AI chatbots as a way to bridge this gap and create a more humanized customer experience.
Counseling Loss as a New Variable in the Education Production Function
Authors: Hornor Tara , Westberry Lee A.
Published: December 2023

The purpose of this qualitative study was to investigate counselling loss as a new variable in the education production function as a result of the COVID-19 pandemic and the associated social and emotional impact on students. Study participants unanimously reported a sizable counselling loss and a 30 percent average decrease in time spent in direct counselling service provision during the COVID-19 pandemic; at the same time, students’ counselling needs increased. Participants identified three salient categories of impact from counselling loss associated with the pandemic, including emotional manifestations, social manifestations, and students’ growth and development-related opportunity loss.
Coaches' benevolent leadership and athletes' psychological wellbeing: The role of caring climate
Authors: Ding Zhichao , Yan Jun
Published: December 2023

The leadership style of coaches plays a vital role in affecting athletes' psychological well-being; however, little is known about the relationship between coaches' benevolent leadership and their athletes' psychological wellbeing. The purpose of this study was to examine the mediating
mechanism of caring climate in the link between benevolent leadership and psychological wellbeing. With a sample of 295 university athletes from three universities in China, we conducted structural equation modeling to test our hypotheses. The results indicated that coaches' benevolent leadership
was positively related to the psychological well-being of athletes, and that caring climate mediated this relationship. Findings from this study highlight the significance of adopting benevolent leadership and creating a caring climate as a means of enhancing the psychological well-being of
university athletes.
POST-PROCEDURAL REHABILITATION: NICE TO DO OR NEED TO DO?
Authors: Kolber Morey , Purita Joseph , Hanney William J.
Published: December 2023

Patients with musculoskeletal disorders who are recalcitrant to formal rehabilitation may seek non-surgical interventions such as orthobiologics. The care pathway following an orthobiologic procedure may include but is not limited to ancillary modalities, supplements, booster injections, and formal rehabilitation. In some cases, the decision to pursue post-procedural rehabilitation may be questioned due to a paucity of evi-dence supporting efficacy and safety following orthobiologic procedures. Moreover, patients and physicians may possess a level of uncertainty in pursuing an intervention that may have been previously unsuccessful. Although higher-level evidence does not exist to support routine post-procedural rehabilitation, a body of evidence supports enhanced physical functioning as well as cellular and molecular effects synergistic to orthobiologics. Given the potential benefits of post-procedural rehabilitation, there would seem to be little downside to participation, provided that the physician and rehabilitation specialist consider individual patient characteristics such as the current pathoanatomical diagnosis, stage of acuity, and pre-morbid activity levels.
EFFECT OF FINANCIAL LITERACY AND FINANCIAL TECHNOLOGY ON MICRO-BUSINESS PERFORMANCE MEDIATED BY FINANCIAL INCLUSION (CASE STUDY OF MICRO-BUSINESSES IN MUARA BULIAN DISTRICT)
Authors: Kusumardiyani Hesti Nila , Setiawati Rike , Wediawati Besse , Hasanah Uswatun
Published: December 2023

This study aims to the Effect of Financial Literacy and Financial Technology on business performance through Financial Inclusion mediation in the subdistrict Muara Bulian. This research is quantitative and the research data used are primary and secondary. The sample is in the subdistrict Muara Bulian, totalling 93 actors. Data collection was carried out by distributing questionnaires with a Likert scale. Data testing techniques use the Validity Test and Reliability Test, R-Square test and Hypothesis Test with Bootstrapping using SmartPLS 3.0 Software. The results showed that Financial Literacy had a positive significant effect on Business Performance, Financial Technology had a positive significant effect on Business Performance, Financial Literacy had a positive significant effect on Financial Inclusion, Financial Technology had a positive significant effect on Financial Inclusion, Financial Inclusion had a positive significant effect on Bussiness Performance, Financial Literacy had a positive significant effect on Business Performance with Financial Inclusion mediation, Financial Technology had a positive significant effect on Business Performance with Financial Inclusion mediation.
FACTORS THAT EFFECT EMPLOYEE PRODUCTIVITY WITH WORK COMPETENCY AS INTERVENING VARIABLE AT FOOD AND BEVERAGE MSMEs IN BATAM
Authors: Lo Mischelle , Setyawan Agustinus
Published: December 2023

Labour is one of the most important things in measuring the competitiveness of a country. Indonesia's workforce is ranked 51 out of 63 studied by the International Institute for Management Development (IMD) in the World Talent Ranking in 2022. This can be seen based on statistical data on the level of labour productivity released in 2022 by the ILOSTAT (International Labor Organization) agency that Indonesia is still in 107th place out of 185 countries at US $ 13.1 per hour. This study was conducted to examine the effect of work discipline and work motivation on employee productivity with work competence as mediation in Food and Beverage MSMEs in Batam. The research method used is a quantitative approach. The research collected respondents using a questionnaire method through gform for 400 samples. The data were analyzed using SPSS to analyze descriptive data and Smart PLS to test research hypotheses. The results showed that the variables of work discipline and work motivation directly affect employee productivity and indirectly affect through work competency.
INFLUENCE OF CUSTOMER EXPERIENCE ON INTEREST USING THE TIX.ID APPLICATION IN PURCHASING CINEMA TICKETS IN JAMBI CITY WITH CUSTOMER SATISFACTION AS AN INTERVENING VARIABLE
Authors: Subhi Ahmad , Erida Erida , Yuniarti Yenny
Published: December 2023

The perpetrator's business can use the internet and digital marketing as a medium for support activities marketing , like For do promotion, buying and selling process. One of them is the emergence of online sites and applications internet-based _ used to help do activity sales or purchase products online. Study This is study descriptive quantitative aim _ To explain the influence Customer Experience and Customer Satisfaction as well as interest_use repeat consumers who have application Tix. Id . Population in research This is user application Tix.Id in Jambi City with sample as many as 75 respondents . Withdrawal sample use non-probability sampling with the technique purposive sampling . Data collection using google form. Deep data analysis techniques study This is Partial Least Square use application SmartPLS . Research results This show that : Customer Experience and Customer Satisfaction influential positive and significant to Interest  Use Repeat , Customer Experience influential positive and significant to Customer Satisfaction. CustomerExperience influence  interest use repeat through customer satisfaction as intervening variable
EFFORTS TO IMPROVE EMPLOYEE PERFORMANCE THROUGH COMPENSATION POLICY AND JOB DESIGN EFFECTIVENESS MEDIATED BY JOB SATISFACTION AT MANDIRI UTAMA FINANCE SERANG BRANCH
Authors: Ratnasari Henny , Rahmansyah Agus David
Published: December 2023

This study aims to determine the relationship between compensation policy variables and the effectiveness of job design in improving employee performance and job satisfaction in mediating compensation policies and the effectiveness of job design in improving employee performance. Building a model of business phenomena and research gaps in improving employee performance at the Serang Branch of Mandiri Utama Finance with a purposive sampling technique. Data analysis using the SEM-PLS method. The results of the study show 1) Steering policies have a positive and significant effect on job satisfaction, 2) Job design effectiveness has a positive and significant effect on job satisfaction, 3) compensation policies have a positive and insignificant effect on employee performance, 4) Job design effectiveness has a positive influence and significant to employee performance, 5) Job satisfaction has a positive and significant impact on employee performance. 6) Job satisfaction mediates the effect of compensation policy significantly on employee performance, 7) Job satisfaction mediates the effect of job design effectiveness significantly on employee performance.
EFFECT OF INFLATION, INTEREST RATE, EXCHANGE RATE, CORRUPTION PERCEPTION INDEX, AND TRADE OPENNESS ON FOREIGN DIRECT INVESTMENT IN 6 ASEAN COUNTRIES
Authors: Fiona Fiona , Laulita Nasar Buntu
Published: December 2023

Every country faced economic instability during the COVID-19 pandemic. Despite the economic instability, some discovered that the number of foreign direct investment inflows increases in most of ASEAN countries. This phenomenon makes investors hard to predict the level of foreign direct investment within the region. The purpose of this research is to understand which are the variables that may have impact on the inflows of foreign direct investment, specifically in ASEAN countries. Therefore, the research is conducted in 6 ASEAN countries that contribute the most to the overall foreign direct inflows in ASEAN from the year 2002 to 2021. This research uses a quantitative approach with panel data regression analysis. This research is tested in both Eviews 12. The result shows that inflation and interest rates don't affect foreign direct investment inflows significantly in the 6 ASEAN countries, whereas exchange rate, corruption perception index, and trade openness have a significant effect on foreign direct investment.
BOOK REVIEW OF POWER IN ORGANIZATIONS BY JEFFREY PFEFFER
Authors: Hasanah Nur
Published: December 2023

This book initiated “new wave” organizational studies that begin to edit, prune, apply, and synthesize what we have to see what we do not have yet, what we have too much of, and what we agree on as the basics. What makes this assessment plausible is the fact that Pfeffer has shown that the several perspectives now dotting the field can converge more strongly on a problem than mere lists of properties can. Pfeffer applies multiple perspectives simultaneously to a durable puzzle in organizations and shows not only that power is less puzzling than we thought but also that all perspectives we are currently working with have something to say about how that puzzle can be untangled most meaningfully. In doing so, Pfeffer has made a major contribution in the form of an important book.
INFLUENCE OF ENVIRONMENTAL ENTREPRENEURSHIP LEVEL AND ENTREPRENEURIAL CHALLENGES ON THE INNOVATION OF WOMEN ENTREPRENEURS
Authors: Sriayudha Yayuk , Musnaini Musnaini , Roza Suswita
Published: December 2023

Entrepreneurship plays a pivotal role in a nation's economic development, and it is essential for women to participate and innovate in this sphere actively. This study seeks to investigate and delineate the following: (1) the correlation between the degree of entrepreneurship, entrepreneurial challenges, the entrepreneurial environment, and the innovation of female entrepreneurs; (2) the interplay between the level of entrepreneurship, entrepreneurial challenges, and the innovation of female entrepreneurs, with the entrepreneurial environment acting as a mediating factor; and (3) the framework of entrepreneurial innovation specific to female entrepreneurs. This research focuses on female entrepreneurs engaged in eco-friendly business practices in the Jambi Province, involving a sample of 200 respondents. A nonprobability sampling technique was employed to select participants. Data collection was carried out using a structured questionnaire. The gathered data was analysed using the Structural Equation Model (SEM/PLS) via the Smart PLS tool. The findings reveal significant links between the degree of entrepreneurship and the entrepreneurial environment, as well as between entrepreneurial challenges and both the entrepreneurial environment and eco-friendly entrepreneurial innovation. The primary goal is to develop an empirical model of eco-friendly entrepreneurial innovation, which can be utilised to promote environmental sustainability by integrating key factors identified in the current study. This research is anticipated to make a significant theoretical contribution to scholars in related fields.
ECO-INNOVATIVE STRATEGIES: ENHANCING ENVIRONMENTAL AWARENESS AND SHAPING CONSUMER PREFERENCES THROUGH GREEN MARKETING
Authors: Nurhidayat Prasetyo , Indah Sonia Melati , Vebiola Ayu , Atmanegara Sandri , Nurhasanah Ana , Octavia Ade
Published: December 2023

This study delves into the burgeoning field of green marketing and its pivotal role in shaping environmental awareness and influencing consumer preferences. Positioned within the realm of marketing management, this research sets the groundwork for developing hypotheses about the dynamics between green marketing and various dependent variables, aiming to guide future empirical investigations. Employing a qualitative descriptive approach, this research synthesizes insights from an extensive review of academic literature, utilizing resources such as Crossref, Google Scholar, and other esteemed academic platforms. The findings underscore two primary impacts of green marketing: (1) a significant influence on consumer environmental consciousness, and (2) a notable effect on consumer preferences. Beyond these key areas, the study identifies additional factors interplaying with green marketing. These include competitive advantage, environmental sustainability, brand image, Eco Labelling, and Eco Branding. These insights contribute to a more nuanced understanding of green marketing's multifaceted influence and highlight potential avenues for further research in the field.
VALUE CREATION IN E-BUSINESS: A STUDY OF TWO B-TO-B COMPANIES
Authors: Efendi Efendi
Published: December 2023

The current study analyzes the study of Amit and Zott (2001) using the nowadays business practices in two B-to-B companies. The companies utilize value constellations strategies in conducting their business. They re-create values for their business customers. The study intends to find new sources of value creation not discovered in Amit and Zott (2001). Amit and Zott (2001) argue that the sources of value creation in e-business are efficiency, complementarities, lock-in, and novelty. The research uses in-depth interview as a tool in qualitative methodology. Two interviews were conducted on the executives from two e-business companies providing services to other companies in the value chain. After analyzing the data, it was found that, there are two new sources of value creation in e-business, which are the value of information and digital ecosystem. The new findings in this research could be due to the focus of Amit and Zott (2001) on B-to-C customers and the absence of fully-fledged digital ecosystem seen in today’s digital platforms.
GROWTH ANALYSIS OF CHINESE LIQUOR LISTED COMPANIES BASED ON PRINCIPAL COMPONENT ANALYSIS
Authors: Luo Jun , Shi Xiaoyu , Liu Jingwei
Published: December 2023

Online shopping has been increasingly popular in recent years due to the spread of the Internet, and the livestream sector has increased. Many traditional companies, such as Chinese liquor enterprises, tried to engage in livestreaming to keep pace with their new customers. The overall perceived value’s impact on user behavior has been examined in social commerce research, but the livestream context has received less attention. This study proposed and empirically tested a theoretical model, considering online word-of-mouth, and investigated the effect of consumer perceived value on livestream purchase intention of Chinese liquor. The findings demonstrate that online word-of-mouth serves as a mediator between the three dimensions of perceived value - functional, emotional, and social value - and livestream purchase intentions of Chinese liquor.
INFLUENCE OF BRAND IMAGE AND LIFESTYLE ON PURCHASING DECISIONS IPHONE IN JAMBI CITY
Authors: Marsyaf Agesha , Rifandi Dimas Ihza , Dani Rian
Published: December 2023

The purpose of this study is first to determine the effect of brand image on iPhone purchasing decisions. The second is to determine the effect of lifestyle on iPhone purchasing decisions. The third is to determine the effect of brand image and lifestyle on iPhone purchasing decisions. The first data analysis method used was the instrument test. Both are multiple linear regressions. The third uses hypothesis testing. The results of this study concluded that brand image and lifestyle influence iPhone purchasing decisions. Both brand image and lifestyle affect iPhone buying decisions. The three brand images and lifestyles simultaneously have a significant effect on iPhone purchasing decisions in Jambi City.
Statement Of Retraction: Emotional Intelligence And Empathy: Predictors Of Counselors’ General Health
Authors: Saifuddin Ahmad
Published: December 2023

We, the editors and publishers, decided to retract the article entitled "Emotional Intelligence And Empathy: Predictors Of Counselors' General Health" with authors Peter Worlanyo Abomah (Department Of Psychology, Methodist University College, Ghana), Gladstone Agbakpe (Department Of Psychology, Methodist University College, Ghana), Cynthia Naa Lamiley Quaye (Department Of Psychology, Methodist University College, Ghana). We published the article in Volume 4 Issue 1 2023 (https://ejournal.uinsaid.ac.id/index.php/ajpc/article/view/7478). The authors were proven to have committed violations in the form of multiple submissions (https://scientific-publishing.webshop.elsevier.com/research-process/paper-retraction-meaning-and-main-reasons/). This article was also published in the International Journal of Natural Sciences: Current and Future Research Trends Volume 20 Issue 1 page 1-17 (https://ijnscfrtjournal.isrra.org/index.php/Natural_Sciences_Journal/article/view/1200). The authors have been informed about the retraction of the article. The retracted articles will remain online, but they will be digitally watermarked on each page as ‘Retracted’.
KONFLIK TEOLOGIS DALAM AL-QU'RAN
Authors: Wahab Abdul Jamil , Hariyadi Muhammad , Tahir Muhammad Suaib
Published: December 2023

Al-Qur’an di dalamnya terkandung ayat-ayat yang memiliki arti perdamaian (āyāt as-silm) dan ayat-ayat yang memiliki arti peperangan (āyāt al-qitāl) atau disebut juga ayat-ayat pedang (āyāt as-saif). Sebagian mufasir berpandangan bahwa ayat-ayat perdamaian itu telah dianulir (di-nasakh) oleh ayat-ayat pedang atau ayat yang memiliki arti peperangan. Pandangan tersebut ditolak oleh mufasir lainnya, karena tidak sejalan dengan misi Islam sebagai agama raḥmatan li al-‘alamīn atau membawa perdamaian. Jika ayat perdamaian dianulir dengan ayat peperangan akan dianggap bahwa Islam melegitimasi adanya kekerasan (violence) dan peperangan atas nama Al-Qur’an. Hal demikian akan menimbulkan persepsi bahwa Al-Qur’an menjadi penyebab lahirnya kekerasan dan peperangan dalam kehidupan masyarakat. Melalui pendekatan mauḍū‘ī, disimpulkan bahwa ayat-ayat peperangan tidak menganulir ayat-ayat perdamaian dan demikian pula sebaliknya. Masing-masing memiliki konteksnya sendiri. Ayat-ayat peperangan turun merespons konflik yang eskalatif antara kaum muslim dengan orang musyrik, ahli kitab, kafir, dan munafīk. Peperangan dalam Islam dibolehkan ketika kaum muslimin dizalimi dan karena diperangi terlebih dahulu oleh orang musyrik atau kafir. Jika tidak dalam peperangan, hubungan sosial antara kaum muslimin dengan non-muslim adalah didasari ayat-ayat perdamaian yaitu, bersikap toleran, sabar, memaafkan, mengalah, tidak mendendam, menghindari perselisihan, berdialog, serta hidup berdampingan secara damai.