bluuebunny/crossref_metadata_2025 huggingface dataset:
Selebriti dan Fandom di Era Media Sosial: Fenomena Selebgram
Authors: Hasna Safira
Published: March 2022

Perkembangan media sosial membuat pergeseran arti selebriti yang semula traditional celebrities yang dapat dikategorikan sebagai aktor, musisi, model, bergeser menjadi “micro celebrities” dan lahir fenomena selebgram atau selebriti Instagram di Indonesia. Oleh karena itu, tujuan penelitian ini adalah untuk mengetahui bagaimana fenomena selebriti Instagram dengan meninjau beberapa konsep yang terkait dengan selebriti dan fandom di era media sosial. Penelitian menggunakan studi kepustakaan yaitu merinci konsep yang berkaitan dengan selebriti, fandom, dan media sosial. Hasilnya, Semakin unik, semakin menarik, atau bahkan semakin kontroversial maka semakin banyak fans yang mereka dapatkan. Konten yang relatable, terlihat nyata, ternyata menjadikan para selebgram diidolakan banyak orang. Layaknya fans pada selebriti tradisional, fans selebgram juga dapat membangun suatu fanbase dan berinteraksi dengan idolanya melalui fitur komentar yang ada dalam Instagram.

Kata Kunci: Selebriti, Mikro Selebriti, Selebgram, Fans, Fandom, Instagram
Use of sunflower gene pool accessions in breeding for high content of oleic acid in oil
Authors: Makliak KM , Leonova NM , Suprun OH
Published: March 2022

The results of using sunflower gene pool accessions (variety-population Kruiz, lines - sterility fixers Kh 1012 B, Mkh 215 B and Kh 52 B) in sunflower breeding for high content of oleic acid in oil are presented. During the period of 2007-2018, 52 self-pollinated lines were created, including 39 lines - sterility fixers and 13 lines - pollen fertility restorers, with high, medium and low content of oleic acid in oil. In 2019-2021, various expression levels of valuable economic and morphological features were determined in 15 lines - sterility fixers. The oleic acid content in oil from seeds of the lines was found to exceed 85%; the "seedlings-flowering" period lasted 53-59 days; the lines were highly resistant to rust, downy mildew and broomrape (parasitic plant). The lines are valuable sources for creating oleic sunflower hybrids.
Estilos de afrontamiento y el bienestar psicológico de los alumnos de Psicología de la Universidad Católica de Santa María
Authors: Quintanilla Acosta Andrea
Published: March 2022

En la actualidad, hablar de estrés es muy común y es importante estudiar las formas de afrontarlo, por eso nuestro objetivo es establecer el tipo de relación entre los estilos de afrontamiento y el bienestar psicológico de los alumnos de psicología de la Universidad Católica de Santa María en Arequipa. Para ello se hizo un estudio correlacional con 120 participantes a los que se les aplicó el Cuestionario de Afrontamiento al Estrés (CAE) y la Escala de Bienestar Psicológico (BIEPS). Para obtener los resultados se aplicó la correlación de Pearson obteniendo que los estudiantes de psicologia que autoperciben un mayor bienestar psicológico utilizan técnicas de afrontamiento de focalización en la solución del problema, revaluación positiva y búsqueda de apoyo social, ya que presentan correlaciones significativas positivas moderadas. Entonces las personas con un elevado bienestar se caracterizaron por analizar la causa de los problemas de un modo sistemático, ver el lado positivo y pedir ayuda.
RACISM IN 42 MOVIE DIRECTED BY BRIAN HELGELAND
Authors: Laksmiati Yuyun Dwi , Sutrisno Bejo
Published: March 2022

This Thesis is an attempt to find the racism that occurred by the man character in 42 movie. There are 3 problems of the study: (1) What are the factors causing the racism in 42 movie? (2) How to determine the racism in 42 movie by Brian Helgeland? (3) What are the effects of racism in 42 movie by Brian Helgeland?. A qualitative methods used to explain about Racism in 42 movie directed by Brian Helgeland. The data were collected from websites, references books, some articles, and the original movie. The writer watched the movie many times to get the point of story in this movie. Put the dialogues or the conversation that related with the main title in this paper to analyze the data. The results of this research indicates: first, the factor of racism are from culture and America history, second,  determining racism by selecting the racism action that occurred between white and black ,the third effect of racism upon the offender and upon the victim, and the last moral message from racism action in 42 movie
Covid-19 And Cardiovascular Disease In The Global Chronic Disease Epidemic
Authors: Martins Ian James
Published: March 2022

The COVID-19 epidemic and global chronic disease epidemic is expected to cost billions of dollars in the next 20 years. The role of various chronic diseases such as NAFLD, diabetes, cardiovascular disease and neurodegenerative disease research may now be relevant to the COVID-19 pandemic with the anti-aging gene repression connected to mitophagy [1,2] and the severity of the COVID-19 and heart disease.
Tangeretin Improves Anxiety-Like Behaviors in a Rat Model of Post-Traumatic Stress Disorder
Authors: Yan He , Gao Huan
Published: March 2022

Post-traumatic stress disorder often contributes to various anxiety-like behaviors. The single prolonged stress was used to induce anxiety-like behaviors of rats. In this model, using an elevated plus maze test, we observed that tangeretin treatment reversed the decrease in the number of open arms entries, the percentage of time spent in open arms with no change in the number of closed arms entries, and percentage of time spent in closed arms in rats subjected to single prolonged stress. Furthermore, in an open field test, tangeretin treatment reversed the decrease in the number of crossing and time spent in the center field with no change in the activities in the peripheral regions. Diminution in serotonin in different parts of brain of rats with post-traumatic stress disorder was reversed by tangeretin. At the molecular level, tangeretin treatment increased the expression of nuclear factor erythroid 2-related factor 2, heme oxygenase 1, and oxidoreductase-1 that was reduced in the post-traumatic stress disorder group in a dose-dependent manner. In conclusion, these studies have shown for the first time that tangeretin relieves anxiety-like behaviors in rats with post-traumatic stress disorder by activating nuclear factor erythroid 2-related factor 2 signaling pathway.
ORGANIZATION OF INDEPENDENT WORK OF BACHELORS IN THE FIELD OF ECONOMICS WHEN STUDYING MATHEMATICS
Authors:   Samara State Transport University, Gumennikova Yu.V.
Published: March 2022

The article notes the importance of independent work of students as an obligatory element of the educational process, discusses the issues of organizing independent work of bachelors-economists when they study mathematics at the Samara State Transport University. A model of organization of independent work of students and its control in preparation for lectures, practical classes, tests and exams, in the performance of control work is given, which allows resolving the contradiction between the need for careful organization of independent work and the teacher's lack of time for its development and implementation. The research materials are applicable to the teaching of full-time students, because. The organization of the IWS of part-time and part-time forms of education differs significantly in the limited time of direct communication between the teacher and students. The SIW is the most important component of the educational process at the university, and therefore the teacher is required to competently and comprehensively organize and control it. The model of organization of independent work of a bachelor proposed in the paper does not require significant labor and time costs from the teacher, while it contributes to the formation of skills and abilities to develop the qualities of students necessary for mastering general cultural and professional competencies.
Система управления работой с одаренными сельскими школьниками
Authors:   ФГБОУ ВО «АлтГПУ», Парфенова Г.Л. , Холодкова О.Г. , Бокова О.А. , Мельникова Ю.А.
Published: March 2022

В монографии обосновывается актуальность и необходимость решения проблемы системного управления работой по развитию одаренных сельских школьников; акцентировано внимание на специфике условий проживания и развития одаренных детей в сельской местности и их обучения в сельской школе; определены трудности, возможности, современные характеристики сельской школы как компонента образовательного пространства региона, с учетом специфики которого должна строиться система управления деятельностью по развитию и психолого-педагогическому сопровождению одаренных детей и молодежи в селе. Представлен обзор зарубежного, российского, регионального опыта управления развитием одаренных детей и молодежи; результаты эмпирического исследования личностных качеств одаренных сельских школьников как показателей их готовности к развитию и самореализации. Издание предназначено для студентов, магистрантов, аспирантов психолого-педагогического направления подготовки, для педагогов, психологов, административных работников образования, занимающихся системными взаимодействиями в вопросах эффективного развития одаренности детей и молодежи.
Analysis of Over-Dispersed Count Data: Application to Obligate Parasite Pasteuria Penetrans
Authors: Vagelas Ioannis
Published: March 2022

In this article we present with STATA regression models suitable for analyzing over-dispersed count outcomes. Specifically, the Negative Binomial regression can be an appropriate choice for modeling count variables, usually for over-dispersed count outcome variables. The common problem with count data with zeroes is that the empirical data often show more zeroes than would be expected under either Poisson or the Negative Binomial model. We concluded, this publications showcases that Zero-inflated models can be used to model count data that has excessive zero counts.
Pengetahuan Perawat Tentang Attraumatic Care Di RSUD Ibnu Sina Bojonegoro
Authors: Ardianti Ikha , Mei Fitria Kurniati
Published: March 2022

ABSTRAK

Prosedur tindakan yang diterima anak merupakan stressor fisik yang dapat membuat anak tidak kooperatif, sehingga dapat menghambat intervensi keperawatan yang akan diberikan. Oleh karena itu penting bagi seorang perawat mengetahui prinsip attraumatic care dalam pemberi asuhan keperawatan pada anak. Attraumatic care adalah prinsip pemberian asuhan keperawatan yang bertujuan untuk mencegah trauma pada anak dan keluarga selama proses hospitalisasi. Tujuan penelitian yaitu mengetahui Mengetahui gambaran pengetahuan perawat tentang attraumatic care di di RSU Ibnu Sina Bojonegoro.

Desain penelitian menggunakan metode deskriptif kuantitatif dengan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah seluruh perawat yang bekerja di RS Ibnu Sina Bojonegoro yang berjumlah 66. Penelitian ini dilakukan pada bulan April-Agustus 2019 sejumlah 32 dengan menggunakan purposive sampling.

Hasil penelitian menunjukkan tidak ada hubungan Usia dengan Kepatuhan Kontrol Gula Darah Pasien Diabetes Mellitus dengan nilai P- value 0.91. Tidak ada hubungan Jenis Kelamin dengan Kepatuhan Kontrol Gula Darah Pasien Diabetes Mellitus dengan nilai P- value 0.681 perawat yang memiliki tingkat pengetahuan tentang atraumatic care berada dalam kategori cukup yaitu sebanyak 14 orang (43,8%), kategori baik sejumlah 9 orang (28,1%) dan kategori kurang sejumlah 9 orang (28,1%).

Anak yang tidak tidak kooperatif selama masa perawatan dapat memperlambat proses penyembuhan. Hal tersebut dapat dicegah dengan penggunaan prinsip atraumatic care dalam pemberian asuhan keperawatan. Oleh karena itu penting bagi seorang perawat mengetahui prinsip attraumatic care dalam pemberi asuhan keperawatan pada anak. sehingga bisa mencegah terjadinya komplikasi dan meminimalkan dampak hospitalisasi.
Excess success in articles on object-based attention
Authors: Francis Gregory , Thunell Evelina
Published: March 2022

Twenty-five years of research has explored the object-based attention effect using the two-rectangles paradigm and closely related paradigms. While reading this literature, we noticed statistical attributes that are sometimes related to questionable research practices, which can undermine the reported conclusions. To quantify these attributes, we applied the Test for Excess Success (TES) individually to 37 articles that investigate various properties of object-based attention and comprise four or more experiments. A TES analysis estimates the probability that a direct replication of the experiments in a given article with the same sample sizes would have the same success (or better) as the original article. If the probability is low, then readers should be skeptical about the conclusions that are based on those experimental results. We find that 19 of the 37 analyzed articles (51%) seem too good to be true in that they have a replication probability below 0.1. In a new large sample study, we do find evidence for the basic object-based attention effect in the two-rectangles paradigm, which this literature builds on. A power analysis using this data shows that commonly used sample sizes in studies that investigate properties of object-based attention with the two-rectangles paradigm are, in fact, much too small to reliably detect even the basic effect.
Open Lab: A web application for running and sharing online experiments
Authors: Shevchenko Yury
Published: March 2022

Online experiments have become a popular way of collecting data in the social and behavioral sciences. However, the high technical hurdles of setting up a server may prevent researchers from starting them. Also, proprietary software may restrict a researcher’s freedom to customize or share their study. Open Lab is a server-side application designed to host online surveys and experiments created using lab.js. Available online at https://open-lab.online, Open Lab offers a fast, secure, and transparent way to deploy studies; it handles uploading experiment scripts, customizing study design, managing the participant database, and working with the study results. Open Lab is integrated with the lab.js experiment builder (https://lab.js.org/), a browser-based program which enables the creation of new studies from scratch or the use of templates. This paper compares Open Lab with other study deployment services, discusses how Open Lab contributes to open science practices, and provides a step-by-step guide for researchers.
Coordination-assembled myricetin nanoarchitectonics for sustainably scavenging free radicals
Authors: Ma Xiaoyan , Gong Haoning , Ogino Kenji , Yan Xuehai , Xing Ruirui
Published: March 2022

Oxidative stress can lead to permanent and irreversible damage to cellular components and even cause cancer and other diseases. Therefore, the development of antioxidative reagents is an important strategy to alleviate chronic diseases and maintain the redox balance in cells. Small-molecule bioactive compounds have exhibited huge therapeutic potential as antioxidants and anti-inﬂammatory agents. Myricetin (Myr), a well-known natural flavonoid, has drawn wide attention because of its high antioxidant, anti-inflammatory, antimicrobial, and anticancer efficacy. Especially regarding antioxidation, Myr is capable of not only chelating intracellular transition metal ions for removing reactive oxygen species, but also of activating antioxidant enzymes and related signal pathways and, thus, of sustainably scavenging radicals. However, Myr is poorly soluble in water, which limits its bioavailability for biomedical applications, and even its clinical therapeutic potential. The antioxidant peptide glutathione (GSH) plays a role as antioxidant in cells and possesses good hydrophilicity and biocompatibility. However, it is easily metabolized by enzymes. To take advantages of their antioxidation activity and to overcome the abovementioned limitations, GSH, Zn2+, and Myr were selected to co-assemble into Myr-Zn2+-GSH nanoparticles or nanoarchitectonics. This study oﬀers a new design to harness stable, sustainable antioxidant nanoparticles with high loading capacity, high bioavailability, and good biocompatibility as antioxidants.
Polymorphism of fucosyltransferase 3 (FUT3) gene is associated with inflammatory bowel disease (IBD) — a systematic review and Meta-analysis
Authors:   Putian University, ZHENG Jiansheng , ZHU Tang
Published: March 2022

Review question / Objective: Polymorphism of fucosyltransferase 3 (FUT3) gene is associated with inflammatory bowel disease (IBD) — a systematic review and Meta-analysis. Condition being studied: This study collected relevant literatures and analyzed the relationship between the polymorphism of the FUT3 genes at rs3745635, rs3894326, and rs28362459 to the IBD with Meta-analysis, in order to further explore the possible mechanism of the polymorphism of the FUT3 gene and IBD.
Analysis of current practical solutions of crime mapping information systems
Authors: Kmeť Roman
Published: March 2022

Crime mapping information systems are currently a commonly used tool by public authorities, primarily for the police, security forces and services, local and regional government, as well as for the inhabitants of a certain territory. The main idea of ​​creating these systems is to monitor and evaluate the current security situation, which is significantly affected by the active or passive activities of the police or other entities dealing with security issues. An important part is also the knowledge of the security situation on the part of the population, in which a certain state of security can evoke a feeling of security and vice versa.
Cascode Current Mirror for a Variable Gain Stage in a 1.8 GHz Low Noise Amplifier (LNA)
Authors: Lee Lini , Sidek Roslina Mohd , Jamuar Sudhanshu Shekhar , Khatun Sabira
Published: March 2022

A high frequency CMOS variable gain low noise amplifier (VGLNA) constructed based on an inductive source degenerated LNA and a cascode current mirror is proposed. The 'variable' concept is to prevent the unwanted saturation phenomenon due to large input signal. A cascode current mirror cell which consumes minimal voltage headroom without sacrificing the accuracy of the circuit is proposed in the circuit. With a 0.18 m CMOS technology, this technique is applied on a VGLNA operating at 1.8 GHz for GSM band application. The simulation results reveal that the maximum gain is 17.29 dB with gain tuning range of 9.56 dB. The noise ¯gure (NF) is less than 0.92 dB with the power consumption of 9.34 mW at power supply of 1.8 V. Comparison with several same operating frequency LNA circuits published show that this work demonstrated among the lowest NF and highest IIP3 with compromise on the gain.
Optimized Ion Implantation Profiles for the p-n Junction Using Forth Moment Approach for Application in High Frequency VLSI Circuits
Authors: Agrawal N. C. , Parida R. K. , Dash G. N. , Panda A. K.
Published: March 2022

The ion implantation based impurity doping profile across a p-n junction can be represented accurately using Pearson's fourth moment approach. The high-frequency characteristics of the reverse biased p-n junction (IMPATT diodes) are computed using different ion implantation profiles. It has been observed that the microwave properties of IMPATT diodes are very sensitive to the change in doping profiles. The optimized ion implantation profiles are suggested for different frequency bands to fabricate the reverse biased p-n junction for application in high-frequency circuits.
A Study on RAT Selection Algorithms in Combined UMTS/GSM Networks
Authors: Wu Leijia , Sandrasegaran Kumbesan
Published: March 2022

The future wireless network is expected to be a heterogeneous system, which integrates different Radio Access Technologies (RATs) through a common platform. A major challenge arising from this heterogeneous network is Radio Resource Management (RRM) strategy. Common RRM (CRRM) has been proposed in the literature to jointly manage radio resources among a number of overlapped RATs in an optimized way. Currently, the RAT selection algorithm is one of the key research areas of CRRM. This paper studies RAT selection algorithms in co-located UMTS/GSM networks. In this paper, a three complex algorithm called IN*VG*Load is proposed based on improvements on the IN*VG algorithm. The simulation results show that the IN*VG*Load algorithm can optimize the system performance in highly loaded combined UMTS/GSM networks. A new algorithm suitable for low to medium loaded UMTS/GSM networks is also proposed and simulation results are presented in this paper.
Statistical Study of Unusual DNS Query Traffic
Authors: Romana Dennis Arturo Ludena , Musashi Yasuo , Nagatomi Hirofumi , Sugitani Kenichi
Published: March 2022

We statistically investigated on the unusual big DNS resolution tra±c toward the top domain DNS server from a university local campus network in April 11th, 2006. The following results are obtained: (1) In April 11th, the DNS query tra±c includes a lot of fully qualified domain names (FQDNs) of several specific web sites as name resolution keywords. (2) Also, the DNS query traffic includes a plenty of source IP addresses of PC clients. Also (3), the several DNS query keywords including speci¯c well-known web sites can be found in the DNS traffic. Therefore, it can be concluded that we can detect the unusual tra±c and bots worm activity (DDoS attacks and/or prescannings) by assuming a threshold based statistifical detection model and checking the several specific keywords of web sites in the DNS resolution traffic.
Comparative Experimental Exploration of Robust Norm Functions for Iterative Super Resolution Reconstructions under Noise Surrounding
Authors: Patanavijit Vorapoj
Published: March 2022

In DIP (Digital Image Processing) research society, the multi-frame SRR (Super Resolution Reconstruction) algorithm has grown to be the momentous theme in the last ten years because of its cost effectiveness and its superior spectacle. Consequently, for a multi-frame SRR algorithm which is commonly comprised of a Bayesian ML (Maximum Likelihood) approach and a regularization technique into the unify SRR framework, numerous robust norm functions (which have both redescending and non-redescending influence functions) have been commonly comprised in the unify SRR framework for increasingly against noise or outlier. First, this paper presents the mathematical model of several iterative SRR based on Bayesian ML (Maximum Likelihood) approach and a regularization technique. Three groups of robust norm functions (a zero-redescending influence function (Tukey’s Biweight, Andrew’s Sine and Hampel), a nonzero-redescending influence function (Lorentzian, Leclerc, Geman&McClure, Myriad and Meridian) and a non-redescending influence function (Huber)) are mathematically incorporated into the SRR framework. The close form solutions of the SRR framework based on these robust norm functions have been concluded. Later, the experimental section utilizes two standard images of Lena and Susie (40th) for pilot studies and fraudulent noise patterns of noiseless, AWGN, Poisson, Salt&Pepper, and Speckle of several magnitudes are used to contaminate these two standard images. In order to acquire the maximum PSNR, the comparative experimental exploration has been done by comprehensively tailoring all experimental parameters such as step-size, regularization parameter, norm constant parameter.
A Distributed Target Localization Algorithm for Mobile Adaptive Networks
Authors: Pak Amin Lotfzad , Rastegarnia Amir , Khalili Azam , Islam Md Kaul
Published: March 2022

Adaptive networks with mobile nodes possess the distributed adaptation abilities in addition to the collective patterns of motion. Thus, mobile adaptive networks have been used in new applications such as modeling the biological networks and source localization. The original mobile adaptive networks needs full cooperation among the neighbor nodes meaning that each node gathers the information from all of its neighbour nodes. This strategy requires large amount of communications per iteration per node. To address this problem, in this paper we propose a mobile diffusion adaptive network with selective cooperation. In the proposed algorithm each node selects a subset of its neighbors so that its steady-state performance be  as close as possible to the traditional mobile diffusion network. Since the selective cooperation reduces the learning rate we also use affine projection algorithm (APA) as the learning rules at the nodes. Our simulation results reveal that the proposed algorithm is able to achieve the same mean-square deviation (MSD) as the original mobile adaptive network but with a lower communication per iteration per node.
Statistical characterization of ischemic stroke lesions from MRI using discrete wavelet transformations
Authors: Karthik R. , Menaka R.
Published: March 2022

The segmentation and characterization of lesion structures from brain Magnetic Resonance Imaging (MRI) slices serves to recognize the degree of the influenced tissues for effective diagnosis and planning in the treatment of ischemic stroke. The different portions of the affected tissues might exhibit different properties in the different imaging modalities. Hence, developing a fully-automatic approach for segmentation of these abnormal structures is considered to be a challenging research issue in medical image processing. This research applies the discrete wavelet transformation of different types for characterizing the properties of the lesion structures from MRI images. The wavelet co-efficients were determined for different levels and the statistical parameters were extracted from it for characterizing the texture properties of the brain tissues. The experimental results were presented for both normal and abnormal MRI datasets. Observations indicate that there was a clear demarcation between the range of values in the statistical features obtained for normal and abnormal images.
Sensor Array Optimization for Complexity Reduction in Electronic Nose System
Authors: Rahman Md. Mizanur , Charoenlarpnopparut Chalie , Suksompong Prapun , Toochinda Pisanu
Published: March 2022

An Electronic nose (E-Nose) can be used to assess food quality and fruit ripeness without personal bias. A set of relevant sensors must be identified to design an effective E-Nose and reduce implementation cost and complexity. The analysis of tropical fruit odour in terms of pattern recognition errors is carried out to determine the minimum number of sensors and their combinations. Two new methods namely 1) principal component loading and mutual information between sensor data, and 2) threshold based approach are proposed in this work to evaluate and optimize the sensor set. Four pattern recognition methods, namely multilayer perceptron neural network (MLPNN), radial basis function neural network (RBFNN), support vector machine (SVM), and k-nearest neighbour (k-NN) are also compared in terms of classification performance. The pattern recognition error of SVM with the optimal set of sensors is as low as 2.78% and that of k-NN is 9.72%. The results conclude that the pattern classification error with MLPNN, and RBFNN is higher than the error from k-NN and SVM.
Analytical Approach and Simulation of GaN Single Gate TFET and Gate All around TFET
Authors: Samuel T.S.Arun , Arumugam N. , Chandra S.Theodore
Published: March 2022

In this work, we investigate the impact of Gallium Nitride (GaN) based Single Gate Tunnel field effect transistors (SG TFET) and Gate All Around (GAA) TFET by using analytical models. The models are derived by solving the 2D-Poisson’s equation and Parabolic Approximation Technique. The analytical model includes the calculation of the surface potential, lateral electric field and vertical electric field. Finally the drain current is extracted by using Kane’s model. The device simulations are carried out using 2-D device simulator, Technology Computer Aided Design (TCAD). The model can be used to study the impact of GaN based SG TFET and GAA TFET in terms of higher ON current characteristics. The results expected by the model are compared with those obtained by 2-D simulation to verify the accuracy of the proposed analytical model.
Computation of Extended Suzuki Mobile Fading Channel (Type I) Parameters
Authors: Al-Ka'bi Amin
Published: March 2022

The analysis and modeling of mobile fading communications channels has been an active research topic since early beginnings of mobile radio systems. In mobile wireless communication systems, the multipath propagation in addition to the movement of the receiver and/or the transmitter leads to drastic and random fluctuations of the received signal. For flat fading channels, the extended Suzuki process of type (I) has been proposed as a stochastic model of such received signal fluctuations. In this paper we discuss this stochastic model and an appropriate deterministic model, and subsequently present and analyze simulation results based on these models. In this paper, a method to mitigate the effect of multipath propagation using an adaptive array antenna is presented. It is shown that by controlling a number of active elements and their spacing the array’s capability to eliminate scattered signals can be enhanced in the presence of pointing errors.
Persepsi Mahasiswa Prodi Sarjana Kesehatan Masyarakat Stikes Dharma Husada Bandung Terhadap Penerapan Adaptasi Kebiasaan Baru Di Masa Pandemi COVID-19 Tahun 2021
Authors: Pamungkas Gugum , Dwi Tamara Metha , Puspita Sari Intan
Published: March 2022

Persepsi merupakan proses pemberian arti terhadap lingkungan atau objek oleh individu. Persepsi yang muncul dari dalam individu ini kemudian menggerakkan masing-masing individu untuk dapat mengatur dan mengelola dirinya dalam menerapkan protokol kesehatan sebagai kebiasaan baru yang diberlakukan di beberapa tatanan pada masa pandemi COVID-19. Tujuan dari penelitian ini adalah untuk mengetahui persepsi mahasiswa kesehatan terhadap AKB pada masa pandemi COVID-19. Pada penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif. Sampel dalam penelitian ini adalah mahasiswa tingkat akhir non regular dan mahasiswa tingkat dua regular, jumlah keseluruhan sampel berjumlah 6 orang. Teknik pengumpulan data yang digunakan adalah wawancara, observasi dan dokumentasi kepada mahasiswa kesehatan. Hasil penelitian menunjukkan Pesepsi mahasiswa kesehatan terhadap penerapan AKB di kampus, terdapat mahasiswa yang berpersepsi bahwa protokol kesehatan yang sudah diberlakukan di kampus masih kurang efektif. Persepsi mahasiswa kesehatan terhadap penerapan AKB di tempat ibadah, hampir semua mahasiswa berpersepsi penerapan AKB di tempat ibadah sudah efektif. Persepsi mahasiswa kesehatan terhadap penerapan AKB di transportasi umum, hampir semua berpersepsi bahwa penerapan protokol kesehatan yang sudah di terapkan pada transportasi umum online seperti Gojek dan Grab sudah cukup baik. Persepsi mahasiswa kesehatan terhadap penerapan AKB di tempat umum, sebagian mahasiswa berpersepsi bahwa penerapan AKB tersebut masih kurang efektif dan kondusif. Persepsi mahasiswa kesehatan terhadap rencana tindak lanjut sebagai mahasiswa kesehatan dalam menghadapi AKB adalah dengan melakukan promosi kesehatan.
ERROR CORRECTION MODEL FOR ANALYSIS OF INFLUENCE OF FISCAL POLICY ON ECONOMIC GROWTH IN EU
Authors: Voda Alina Daniela , Dobrotă Gabriela , Dobrotă Dan , Dumitrașcu Dănuț Dumitru
Published: March 2022

Ensuring fiscal sustainability in the Member States of the European Union has become an extremely important goal in the current economic context. The formulation of appropriate policies can lead to fiscal consolidation, and the manifestation of a fiscal shock with direct implications on national budgets and can be mitigated by a rational approach. The aim of this paper is to examine issues related to ensuring fiscal sustainability and to identify the necessary fiscal policy instruments in this regard. Using a data set for EU member states for the period 2000–2019, we researched fiscal policy objectives for economic development and the volume of public and private investment. The error correction model (ECM) was used as a derivative of the autoregressive model with distributed lags (ARDL) to assess the short-term variation of Gross Domestic Product under the influence of seven fiscal indicators. The study highlights the aspects of fiscal policies at EU level as well as the correlation between economic development and the fiscal behaviour of the authorities. We contribute to the existing literature by providing empirical evidence on the existence of a direct relationship between economic growth and the volume of private investment.
Black Seed (Nigella sativa) Efficacy in Improving Clinical Symptoms and Interleukin-6 Levels Schizophrenic Patients
Authors: Purwatiningsih Sri , Syamsuddin Saidah , Lisal Sonny T. , Liaury Kristian , Bahar Burhanuddin , Yustisia Ika
Published: March 2022

BACKGROUND: Schizophrenia with a global prevalence of 0.33–0.75% and one of the top 15 causes of disability. The etiology underlying this disease is still controversial. One of the causes is the Vulnerability Stress-Schizophrenia Inflammatory Model which shows an increase in pro-inflammatory cytokines, one of which is Interleukin-6 (IL-6).

AIM: It is hoped that through the adjuvant anti-inflammatory effect of black seed or Nigella sativa can improve the clinical symptoms of schizophrenia and reduce levels of Serum IL-6 as a marker of therapeutic efficacy, as well as observing the effect of treatment on liver function.

METHODS: The present study was conducted 22 schizophrenic patients hospitalized at the psychiatric hospital (Rumah Sakit Khusus Daerah) of South Sulawesi aged 20–45 years and received risperidone 4 mg/day therapy. Patients were divided into two groups, the control and treatment groups received N. sativa 1000 mg/d for 4 weeks. Each group was measured for baseline and week 4 clinical symptoms of schizophrenia with Positive and Negative Symptom of Schizophrenia (PANSS) and serum IL-6 levels. The analysis also measured serum IL-6 levels in 14 healthy people by assessing the side effects of N. sativa adjuvants by measuring liver function enzymes of Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT).

RESULTS: Serum IL-6 levels of schizophrenic patients were higher than healthy controls. Administration of adjuvant N. sativa 1000 mg for 4 weeks significantly p < 0.001 improved PANSS value, decreased serum IL-6 levels 2.5 times faster in the treatment group and did not give a significant change in SGOT and SGPT values.

CONCLUSION: This study suggests that N. sativa may consider as an adjuvant therapy to improve clinical symptoms of schizophrenia and reduce levels of IL-6 was faster than control group and is safe for liver function.
Expression of Stanniocalcin-1 as a Predictor of Recurrence in Breast Cancer Patients
Authors: Prajoko Yan Wisnu , Hastari Rizka , Muniroh Muflihatul , Puspasari Dik
Published: March 2022

Introduction: About 40% of breast cancer patients will experience a recurrence and the life expectancy will decrease from 95% to 40%. Stanniocalcin-1 is a biomarker that is thought to have potential as a risk factor for recurrence.
Objective: To determine the role of Stanniocalcin-1 (STC1) expression as a risk factor for recurrence in breast cancer patients.
Methods: Cross sectional observational study on breast cancer patients, assessed the clinicopathological character and seen whether the patient's condition had a recurrence. Immunohistochemical staining with STC1 antibody was performed on the patient's paraffin block. Reading of immunohistochemical preparations using the Allred score method by looking at 5 fields of view. Data analysis regarding the relationship between STC1 and recurrence was carried out using the Chi-Square test or Fisher's Exact test, then Logistic regression analysis was performed to determine the significant relationship between risk factors for recurrence.
Results: Expression of STC1 was significantly different in patients who had recurrence and who did not experience recurrence (p= 0.000). There was a significant relationship between STC1 expression with age, tumor size, lymph node status, type of cancer, estrogen receptor status and stage at diagnosis. (p<0.005).
Conclusion: It can be concluded that STC1 has a strong relationship with recurrence, so it has the potential to be used as a predictor of recurrence in breast cancer.
Correlation between Insulin Resistance with Soluble CD40 Ligand and Plasminogen Activator Inhibitor-1 Plasma in Pre-diabetic Patients
Authors: Decroli Eva , Afriant Rudy , Kam Alexander , Puspita Upi
Published: March 2022

BACKGROUND: The main condition of pre-diabetes is insulin resistance that can lead to a prothrombotic state.

AIM: This study aims to correlate insulin resistance with soluble CD40 ligand (sCD40L) and plasminogen activator inhibitor-1 (PAI-1) plasma in pre-diabetic patients.

METHODS: This study is an analytic observational study with a cross-sectional approach. HOMA-IR assessed insulin resistance, and prothrombotic factors were assessed by PAI-1 and soluble CD40L. PAI-1 and sCD40L were examined by ELISA. These indicators were assessed on 30 pre-diabetic patients.

RESULTS: Thirty subjects included in this study with a mean age of 31.47 (5.03) years old, consist of 19 (63%) men and 11 (37%) women. The mean HOMA-IR was 3.69 (1.12), PAI-1 was 10.25 (3.72) ng/mL, and the PAI-1 levels were increased (>8.4 ng/mL) in 70% of the subjects. The mean of sCD40L levels was 4495.7 (1136.3) pg/ml, and sCD40L levels were increased (>4000 pg/ml) in 63% of subject. There was a significant correlation between HOMA-IR levels and sCD40L (r = 0.636, p < 0.05) and between of HOMA-IR and PAI-1 (r = 0.742, p < 0.05). Moderate correlation was found between sCD40L levels and plasma PAI-1 (r = 0.592, p < 0.05) in pre-diabetic patient. The correlation between three variables was HOMA-IR had a significant effect on PAI-1 levels through sCD40L (t = 2.010, p < 0.05, structure loading factor = 0.286).

CONCLUSION: Insulin resistance has a strong and significant correlation with sCD40L and PAI-1 levels in pre-diabetic patients.
Analysis of Zinc and Copper Serum Levels in Premature Hair Graying at Young Age
Authors: Anggraini Dwi Rita , Feriyawati Lita , Sitorus Mega Sari , Syarifah Siti
Published: March 2022

BACKGROUND: Premature canities or premature hair graying is a terminology for early hair graying at an unusual age, with unclear etiology. The pathogenesis of graying is multifactorial such as genetic, environmental, and nutritional factors. The risk factor of premature graying is a deficiency of micronutrient serum such as zinc, copper, and selenium.

AIM: The aim of the present study was to examine the role of zinc and copper serum concentrations in premature hair graying as well as the relationship between them.

MATERIALS AND METHODS: This study was a cross-sectional recruited 40 consecutive respondents suffering from premature graying and healthy controls, male sex and aged <25 years. The serum samples were collected to detect zinc and copper with atomic absorption spectrophotometry.

RESULTS: The mean age of cases was 20.28 ± 1.99 years and controls were 21.25 ± 2.02. Zinc serum concentration was significantly lower in premature hair graying compared with controls (0.48 ± 0.19 vs. 1.92 ± 0.68 ug/dL, p = 0.001) while copper serum concentration was not significantly lower in premature hair gray compared with controls (0.08 ± 0.03 vs. 0.09 ± 0.18 ug/dL, p = 0.706).

CONCLUSION: A low zinc serum level may contribute to premature hair graying of college students at Universitas Sumatera Utara.
Correlation of Patient Generated-subjective Global Assessment with Serum C-reactive Protein Level in Stage I–IV Head-and-neck Cancer
Authors: Siregar Anastasya , Chandra Dian Novita , Rinaldi Ikhwan
Published: March 2022

AIM: This study aims to identify the correlation between patient generated-subjective global assessment (PG-SGA) with serum C-reactive protein (CRP) to be used to predict inflammation and prevent cachexia in head-and-neck cancer patients.

METHODS: This was a cross-sectional study using 51 patients with inclusion criteria of patients diagnosed with head-and-neck cancer irrespective of stage, age ≥18 years old, had not received treatments of radiotherapy, chemotherapy, and surgery. The statistical analysis performed was Kolmogorov–Smirnov normality test, bivariate analysis by Spearman test, and linear regression analysis.

RESULTS: As many as 64.7% of the patients had PG-SGA score ≥9 (average PG-SGA score 11.7 ± 6.2). The CRP median value was 6.4 (0.4–170.4) mg/L. There was a statistically significant positive but weak correlation between PG-SGA score with serum CRP (r = 0.372 and p = 0.007) and a significant linear relationship (r2 = 0.201).

CONCLUSIONS: Malnutrition risk assessment using PG-SGA showed a high prevalence of malnutrition risk in head-and-neck cancer patients. PG-SGA score is correlated with serum CRP level. Further studies are needed to confirm the result of this study.
Anti-mullerian Hormone Serum Level as a Predictor of Responsiveness to Clomiphene Citrate Therapy in Iraqi Women with PCOS
Authors: Rashid Dhai , Bardan Raghda
Published: March 2022

BACKGROUND: Ovulation induction in polycystic ovarian syndrome is one of the most common interventions used in the treatment of infertility and prediction of the response is very important. Although the serum anti-mullerian hormone (AMH) concentrations are known to be a reliable predictor of ovarian response in in vitro fertilization, in women with polycystic ovary syndrome (PCOS) with a higher level of AMH ovulation induction by clomiphene citrate may be not enough to increase the level of follicle-stimulating hormone and reduce the intraovarain AMH to a level that compatible with the restoration of ovulation.

AIM: Our study aimed to identify those females who will respond to treatment and the starting dose of anti-mullerian hormone serum level as a predictor of responsiveness to clomiphene citrate therapy in Iraqi women with PCOS.

METHODS: 79 females with polycystic ovarian syndrome were included in the study. AMH serum concentrations were determined on the second or 3rd day of the early follicular phase of the menstrual cycle before initiating clomiphene citrate in the first treatment cycle.

RESULTS: The females were falling-out into two groups according to their response to treatment. The patient who ovulated had a significantly lower AMH level among responders 7.89 +−3.2 compared to non-responder 9.41 +−3.27. The women who responded at 50 mg dose had lower AMH 6.56 +−2.2 compared to women who responded at 100mg clomiphene citrate had AMH of 8.74 +−3 with optimum cutoff value for AMH is 6.25 to respond.

CONCLUSION: Serum AMH level measurement prior to treatment initiation in women with PCOS may be a useful method for predicting the outcome of clomiphene citrate treatment, and for each specific ethnic group, there is a cutoff value for AMH above which the response to clomiphene citrate is impaired.
Stage specific expression of angiotensin-converting enzyme and thickened lamina propria in relation to male fertility
Authors: Pencheva Mina , Koeva Yvetta , Pavlova Ekaterina , Atanassova Nina
Published: March 2022

Introduction: The testis is an immune privileged organ that provides a specific environment for germ cell development. Various factors responsible for inflammatory changes can lead to deterioration of the immune tolerant model found in the testis. As a result, the thickness of the proper membrane of seminiferous tubules changes and the process of spermatogenesis is disturbed. 

Aim: The purpose of the present study was to find the connection between the changes in the level of testis-specific isoform of angiotensin-converting enzyme (tACE) expression and the morphological changes of the seminiferous tubule wall of the testis in patients with infertility.

Materials and methods: The study included 24 infertile men who underwent a testicular biopsy. Routine histological techniques, immunohistochemical reactions for tACE, α-smooth muscle actin, and morphometric analysis were performed to examine the biopsy preparations.

Results: By using testicular biopsy to diagnose patients with infertility, a stage-specific pattern of the processes associated with thickened proper membrane of seminiferous tubules was established and a decreased or absent spermatogenic activity was observed.

Conclusions: A significant increase in the proper membrane thickness of the seminiferous tubules in the testis was found in patients with infertility. This finding shows that the processes take place gradually over time, correlating with the degree of pathology, and that changes do not depend on the factors causing them. We also found that the degree of proper membrane thickening correlated with disturbances of spermatogenesis, using tACE expression as a marker for spermatogenic epithelium differentiation. 
Advantages and disadvantages of laparoscopic inguinal hernia repair (hernioplasty)
Authors: Trokovski Nikola , Uchikov Petar , Yordanov Emanuil , Atliev Kiril
Published: March 2022

Aim: The aim of this study was to explore the advantages and disadvantages of laparoscopic hernioplasty by comparing them with conventional surgeries.

Materials and methods: The study included 376 patients (344 men and 32 women) who underwent inguinal hernia repair in inpatient settings over a 3-year period (2017–2020). The patients were divided into two groups: patients with conventional hernioplasty (CH) - 312 patients (291 men and 32 women, mean age 55±15 years, range 18–93) and 64 patients with laparoscopic hernioplasty (LH), all of them middle-aged men at mean age 45±15 years (range 24–69).

Results: Thirty-eight patients (59.38%) with LH were ASA class 1 patients while the CH patients were stratified in ASA classes 1 to 4. The LH group consisted of 39 patients who had transabdominal preperitoneal (TAPP) surgery and 25 who received total extraperitoneal (TEP) repair. The average operating time was 12 minutes (range 90–200 min) for TAPP and 50 minutes (range 20-125 min) for TEP. The mean intensity of pain score measured by VAS (0-10) was 4 (2-5) for CH patients and 3 (2-4) for LH patients. The duration of pain was 3 days (2-4) for CH patients and 2 days (1-3) for the LH group. Ninety-five percent (61/64) of LH patients defined their quality of life as “better”.

Conclusions: The following factors are of particular importance for the choice of hernioplastic technique: operating time, possible intraoperative complications, the level of postoperative pain and potential postoperative analgesics, possible complications, patient recovery, length of hospital stay, cost, quality of life, and long-term results of the treatment.