bluuebunny/crossref_metadata_2025 huggingface dataset:
Gelatinous Drop-Like Corneal Dystrophy in an Acehnese Family: Serial Cases.
Authors: Samira Cut Putri , Akbar Muhammad Khalil
Published: February 2024

Introduction : Gelatinous drop-like dystrophy (GDLD) is a rare type of corneal dystrophy with an autosomal recessive inheritance pattern. Although the prevalence in Japan is approximately 1 in 33,000, it is much less common in other nations. Lamellar or penetrating keratoplasty is needed for most patients to alleviate the symptoms. This case series aims to provide knowledge regarding rare cases of GDLD and its management.

Case Illustration : Three male siblings from consanguineous marriage were found to have corneal dystrophy, characterized by a white-yellow nodular lesion with a kumquat-like appearance on the corneal surface. The visual acuity of each patient was light perception with good projection. To treat the condition, all patients underwent full-thickness penetrating keratoplasty. One month after the procedure, their visual acuity had improved to 3/60, 2/60, and 2/60, respectively.

Discussion : GDLD is a genetic disease with gelatinous amyloid deposits in the cornea that typically manifests within the first decades of life. GDLD can present in three different phenotypes, including band keratopathy, mulberry, and kumquat-like appearance. In the case of these siblings, they have developed the severe kumquat-like phenotype. Detection by examining family involvement and the cornea's clinical presentation can help diagnose GDLD. Full-thickness penetrating keratoplasty can be an option for managing severely impaired visual acuity caused by GDLD.

Conclusion : GDLD is a rare corneal dystrophy that can lead to severe visual impairment. The objective of treating GDLD is to enhance vision and prevent its progression. Vision loss can be alleviated througha surgical procedure such as full-thickness penetrating keratoplasty.
CHARACTERISTICS AND MANAGEMENT OF PEDIATRIC CATARACT AT UNIVERSITAS TANJUNGPURA HOSPITAL 2019-2021
Authors: MUHAMMAD ASRORUDDIN  , WIWIK WINDARTI  , YESSLYN YULIANTO
Published: February 2024

Abstract

Introduction & Objectives : One of the causes of blindness in children that can be treated is cataracts. The prevalence of childhood cataracts in Asia is the highest in the world at 7.43 per 10,000 children. There were 4,270 children in Indonesia who experienced blindness due to cataracts in 2017. Data on childhood cataracts in West Kalimantan is still limited. However, the prevalence of blindness in West Kalimantan is the highest in Indonesia at 1.6%. Characteristics of pediatric cataract patients need to be known to assist in diagnosis and treatment so that the risk of blindness in children can be prevented. This study is to describe cataracts in children at Universitas Tanjungpura Hospital in 2019-2021.

Methods : This study used a cross-sectional descriptive design. Data collection was obtained from the medical records of pediatric cataract patients at the Universitas Tanjungpura Hospital during 2019-2021.

Results : The total number of pediatric cataract patients obtained from medical records during 2019-2021 was 27 patients, consisting of 8 girls and 19 boys. Congenital cataracts were the most common cataracts (59%) and the most diagnosed age was in the 0-1 year group. Bilateral cataracts (48%) were almost as numerous as unilateral cataracts (52%). The most common visual acuity before and after surgery was fixating and following object (60%).

Conclusion : Cataracts in children at Universitas Tanjungpura Hospital in 2019-2021 were dominated by congenital cataracts, diagnosis age was at 0-1 years, bilateral and unilateral, male gender, and visual acuity before and after surgery was fixating and following object.
Monocular Electrical Cataract: A Case Report
Authors: Ey Merry Giovedi , Dewanto Erry , Prastayani Reni
Published: February 2024

Introduction : An electric shock is experienced when an electric current passes through a part of the body from an entry point to an exit point. Cataract is frequently described as a complication of electrical injury and it is usually bilateral. We report a rare case of high voltage electric injury in young male patient resulting in monocular cataract.

Case Illustration : A 23 years old man was presented with a diminution of vision one year after sustaining an overhead high voltage power transmission wire that stung his head. The visual acuity of the right eye was hand movement dan 1.0 in the left eye. On slit-lamp examination, opacities were presented in the lens of the right eye and a clear lens in the left eye. Being diagnosed as having monocular cataract, the patient was then performed phacoemulsification on his right eye (April 12th 2023). The pupil shrank until 5 mm during the surgery but foldable IOL was successfully inserted in the capsule. The right eye vision was improved to 0.5 one day after surgery.

Discussion : The consequences of high-voltage electric burns are complex. Electrical shock can cause protein coagulation and cataract formation. Lens manifestations are more likely when the transmission of current involves the patient’s head. Proper management of electrical cataracts will result in good visual rehabilitation if the eye does not suffer additional damage as in this case.

Conclusion : Secondary cataract formation due to electric injury may occur, therefore routine examinations with the ophthalmologist are needed after the electrical trauma. The incidence of monocular cataracts after the electric injury is rare.
Prostaglandin analogs regimen for open-angle glaucoma or hypertensive ocular, is it still effective nowadays?: a systematic review
Authors: Tikha Fidya Ainun , Rahadi Aditia Rizka
Published: February 2024

Introduction & Objectives : Open-angle glaucoma and hypertensive ocular therapy are still developing. There are new medications that offer fast and safe in lowering intraocular pressure. Prostaglandin analogs regimenis a well-known medication that we use in lowering intraocular pressure and still use in this era.

Methods : A literature search was performed in PubMed, Chocraine, and Google Scholar for studies that fit our inclusion criteria. The Literature must be Randomized controlled trials, Systematic reviews, and meta-analyses from 2013 until 2023 that report data on prostaglandin analogs regimen uses medications for open-angle glaucoma or ocular hypertension. That consists of data on intraocular pressure (IOP) lowering effect by the use of prostaglandin analogs regimen monotherapy or combination.

Results : We included Ten literature that consists 5 RCTs (1514 participants), and 5 systematic reviews with meta-analysis (235 RCT literature), that overall make intraocular pressure (IOP) reduction. There are differences in duration to reduce IOP between prostaglandin analogs regimen types and combinations with other classes of regimen.

Conclusion : prostaglandin analogs regimen effective in IOP lowering effect in open-angle glaucoma and hypertensive ocular both monotherapy and combination.
BARRAGE LASER PHOTOCOAGULATION IN HIGH-MYOPIC PATIENT WITH SYMPTOMATIC RETINAL TEARS BEFORE PHACOEMULSIFICATION: A CASE REPORT
Authors: Budhiastra I Putu , Tridiyoga Komang Putra , Jayanegara I wayan Gede , Suryathi Ni Made Ari , Andayani Ari , Pitanatri Nyoman Brahmani
Published: February 2024

Introduction : Retinal tears can be present in up to 2.4% of cases of lattice degeneration, which is considered an important risk of retinal detachment in a high-myopic patient. Laser photocoagulation has been shown to reduce the risks of retinal detachment before phacoemulsification thus improve in the visual outcome. We report a case of a high myopic patient with symptomatic retinal tears who underwent phacoemulsification that was treated prophylactically with barrage laser photocoagulation.

Case Illustration : A 43 years-old female with a history of high myopia complained of flashes and floaters on both eyes. She had high myopia measuring -13.0 dioptres and -28.0 dioptres in the right and left eyes respectively. Unaided visual acuity was 2/60 in both eyes. Fundus examination showed lattice degenerations with a small tear found on both eyes with no retinal detachments. She was treated with a barrage laser on both eyes followed by phacoemulsification. On the last follow-up, the retina remained stable and the visual acuity was significantly improved with no development of macular edema or retinal detachment in both eyes.

Discussion : Although most cases of lattice degeneration do not need intervention, some present a risk of retinal detachment. Barrage laser photocoagulation may have a place in high myopic patient lattice degeneration with symptomatic retinal tears to maintain retinal stability and to obtain the optimal outcome after phacoemulsification.

Conclusion : Barrage laser photocoagulation is beneficial as a prophylactic treatment of symptomatic retinal tears before phacoemulsification in high-myopic patients.
Inteligência Artificial em Cardiologia: do Teorema de Bayes às Redes Neurais de Aprendizado Profundo
Authors: Larissa Gonçalves Coutinho  , João Paulo dos Santos Mauler  , Daniel Gomes Braga dos Reis  , Marcelo Góes Alves da Silva
Published: February 2024

Este artigo de atualização tem como objetivo fornecer uma revisão sobre a evolução e o estado atual da inteligência artificial com foco nas suas aplicações em cardiologia. Recapitulamos sucintamente o histórico da inteligência artificial, desde as suas primeiras aplicações, passando pelos sistemas históricos baseados em lógica bayesiana até as recentes evoluções no que tange ao aprendizado de máquina, aprendizado profundo e as aplicações da ciência de dados e “big data”. Descrevemos achados de recentes estudos sobre o tema, que demonstram a grande aplicabilidade da ciência da computação à prática médica, auxiliando a tomada de decisão e na interpretação de exames de imagem através das redes neurais. Relatamos como os modelos de inteligência artificial já ajudam o processo de tomada de decisão médica em cardiologia e como, no futuro, este processo poderá sofrer uma radical mudança de paradigma, o princípio do qual já estamos testemunhando.
Abordagem Ortopédica das Fraturas Supracondilares do Úmero na Infância
Authors: Marcos Almeida Matos
Published: February 2024

As fraturas supracondilares do úmero na infância são importantes pela sua alta prevalência e especialmente importante para médicos pelo mesmo motivo além de multiplicidade de opções terapêuticas e possibilidade de sequelas irreversíveis. Essas fraturas possuem incidência de 1,7 por mil e representam 15% de todas as fraturas pediátricas, perfazendo 50 a 70% das que ocorrem no cotovelo. Lesões vasculares ocorrem em 10 a 20% e lesões nervosas estão presente em 12,7% a 16,6% das fraturas. São diferenciadas em dois tipos principais: extensão e flexão. Lesões em extensão são classificadas em quatro tipos: Tipo I, Tipo II (divididos em A e B), Tipo III e Tipo IV. O tratamento conservador é realizado de forma global em cerca de 90% das fraturas supracondilares. Fraturas do Tipo I são tratadas com gesso axilopalmar por quatro a seis semanas. Lesões do Tipo IIA e IIB majoritariamente são tratadas por redução, utilizando o arco C e sob anestesia, sendo o gesso axilopalmar suficiente na maior parte dos casos, contudo aproximadamente 15% necessitam de fixação com pinos e/ou redução aberta. Fraturas do Tipo III ou IV devem ser tratadas com fixação por fios ou pinos e a redução aberta pode ocorrer em 16,7 a 23,33% dos casos. A redução aberta pode ser realizada por via posterior ou anterior e a fixação pode utilizar pinos laterais divergentes ou medial e lateral cruzados. As principais complicações destes métodos são a perda da redução e as lesões neurológicas, especialmente do nervo ulnar.
C-Reactive Protein as a Prognostic Indicator: Navigating the Challenge of Predicting Severity and Mortality in Acute Pancreatitis
Authors: Rahman Ibadur , Saleem Hira , Muhammad Burhan ul Haq  , Muhammad Adnan Khokhar  , Arif Khurshid  , Zulfiqar Khan Tanoli  , Shaharyar Ahsan
Published: February 2024

Objective: The main goal was to evaluate the effectiveness of C-reactive protein (CRP) in assessing acute pancreatitis severity 48 hours after onset by contrasting its results with CT scans.

Methodology: This cross-sectional study, which lasted six months from May to December 2019 at the Department of General Surgery, Pakistan Institute of Medical Sciences, comprised 150 suspected cases. CT scans and serum samples were taken 48 hours after the onset of symptoms. A postgraduate trainee created reports using a standard proforma to record CT scan results and CRP levels.

Results: The average age of the patients was 45.03±10.86 years, with severe acute pancreatitis confirmed in 28.7% of cases by CT scans. CRP demonstrated notable diagnostic values: sensitivity 81.4%, specificity 92.52%, PPV 81.4%, NPV 92.52%, and an overall accuracy of 89.33%.

Conclusion: C-reactive protein (CRP), a product of interleukin-1 and interleukin-6 responses by the liver, emerges as a valuable and cost-effective biomarker. Its consistent elevation in correlation with pancreatitis severity, especially within the critical 48-hour window, suggests its potential as a reliable predictor. This study underscores CRP's diagnostic utility and accessibility, emphasizing its role in assessing acute pancreatitis severity.

 

Key Words: C-reactive protein, CT scan, Acute pancreatitis
IMPLEMENTASI E-GOVERNMENT DALAM PELAYANAN PINDAH KELUAR KOTA/KABUPATEN ATAU PROVINSI DI KELURAHAN BONGKARAN SURABAYA
Authors: Rachmad Amalia Ramadhani , Hardjati Susi
Published: February 2024

Surabaya is the provincial capital and one of the largest cities in Indonesia. Because of its high migration flow, immigrants and migrants in Surabaya require population administration services. In compliance with Presidential Regulation Number 6 of 2001, the Surabaya City Population and Civil Registration Service, which organized population administration (adminduk), implemented e-government by offering a variety of conveniences, including administrative service innovations like e-Klampid, which later became Klampid New Generation (KNG). The purpose of this study is to investigate how e-government is being implemented in provinces, cities, and districts with innovative programs like Bongkaran Village, and Surabaya City's Klampid New Generation (KNG) program. Researchers employ qualitative approaches in their work; these methods are qualitative and descriptive in nature. The PAN Ministerial Decree No. 63 of 2003, which addresses the Principles of Public Services, is the theoretical foundation for this study. The result of the research found that Bongkaran Subdistrict's e-government implementation, which utilizes the KNG program for inter-city/regency or provincial transfer services, is performing well in terms of service procedure, cost, time, officer competency, facilities, and infrastructure indicators.
Dependence of sensitivity loss on organic film thickness and influence of cantilever warpage in a piezoelectric wideband acoustic sensor coated with an organic film
Authors: Kuchiji Hiroyuki , Masumoto Naoki , Morishita Kota , Hasegawa Shunta , Suzuki Takaaki , Baba Akiyoshi
Published: February 2024

A wideband acoustic sensor is reported, comprising a piezoelectric MEMS acoustic transducer with organic film-coated cantilevers. Considering the sensitivity reduction associated with the application of an organic film, it is necessary to optimize the material selection and thickness of the organic film. Therefore, the relationship between the thickness of the polyurethane film and the consequent loss in sensitivity is elucidated. Our findings demonstrate that the polyurethane film thickness should be approximately 0.5 μm (or less) to limit sensitivity loss to 6 dB. Additionally, both simulations and experimental results reveal that the resonant frequency of the system is significantly influenced by the warpage of the cantilever. This study provides essential insights into optimizing the performance of MEMS acoustic transducers with organic film-coated cantilevers.
Providing Guidance to Software Practitioners: A Framework for Creating KPIs
Authors: Fatima Iffat , Funke Markus , Lago Patricia
Published: February 2024

Monitoring performance in organizations can act as a catalyst for (i)
fostering a culture of continuous improvement over-time, and (ii)
achieving their overarching business goals. To this aims, organizations
employ Key Performance Indicators (KPIs). However, a common pitfall is
the collection of excessive data which is partially disconnected from
the business goals. In this study, we propose a KPI framework in the
form of a model, an associated template, and a checklist with the aim of
providing guidance to practitioners for creating sound KPIs. We examine
KPI development and monitoring through four case studies in the context
of software systems in two organizations. Through these case studies, we
evaluate our KPI framework for its utility in practice and gain insights
to uncover related challenges.
Neurogenic Myositis Ossificans of the Hip in a Bedridden Patient with Neurofibromatosis
Authors: Mhaili Jihane , Chbichib Chada , Hajjami Youssef Bouktib Ayoub El , Boutakioute Badr , Idrissi Meriem Ouali El , Ganouni Najat Cherif Idrissi El
Published: February 2024

Neurogenic myositis ossificans is an uncommon condition characterized by the formation of heterotopic bone in the periarticular soft tissues of individuals who have paraplegia or tetraplegia due to neurological disorders, frequently occurring after head or spinal cord injuries. Diagnosis relies on imaging, particularly CT scans, which commonly show the appearance of bony formations within the muscles around joints. Management involves the use of pain relievers, physical therapy, and surgery as a final option.
Epidemiology and Antibiotic Resistance of Enterobacteriaceae Isolated in Urinary Tract Infections at Oued Eddahab Military Hospital Agadir
Authors: Mouline Souhail , Jendouzi Omar , Assoufi Naoufal , Alayoud Ahmed , Azizi Mounia
Published: February 2024

Objective: Determine the current bacteriological profile of urinary tract infections and the antibiotic resistance of the main enterobacteria isolated in urine. Methods: Retrospective study over a period of 18 months from January 1, 2022 to June 30,2023 including all urinary cytobacteriological examinations of patients hospitalized in the various departments of the Oued Eddahab Military Hospital in Agadir, as well as outpatients. Results: Out of 4483 urine samples, 487 met the criteria for UTI (10.86% of total samples). The microorganisms were predominantly Enterobacteriaceae (421/487 86.44%). Of the infections, 75% originated from outpatients. The sex Ratio F/M was 1.35. E.Coli dominated the epidemiological profile for both inpatients and outpatients (63% vs. 77%). There was a high frequency of resistance to the main families of antibiotics, while quinolones, fosfomycin, nitrofurans, and aminoglycosides retained good activity. Resistance to third-generation cephalosporins through the production of extended-spectrum betalactamase was present in 09% of Enterobacteria. Finally, no resistance to imipenem and colistin was detected.
Malignant Adnexal Carcinoma of the Face: A Case Report
Authors: Olaya Hamidi , Hassene Zeine Abidine Baba , Bouchra Dani , Malik Pr Boulaadas
Published: February 2024

Malignant adnexal tumors (MAT) form a group of rare, typically low-grade- malignancy carcinomas with follicular, sebaceous, apocrine, or eccrine differentiation or a combination of the first 3 subtypes, the biopsy is required to establish the differentiation subtype and the definitive diagnosis. our case is a 67 years old female presented to our department of maxillofacial surgery of Ibn Sina hospital in Rabat with a left frontal skin lesion that had begun evolving 6 months ago. An excisional biopsy was performed afterwards using an elliptical excision with 1 cm of margins laterally and including the periost deeply, and then the sking defect was sutured in 3 layers. Malignant pilosebaceous tumors are more rare, especially those of the hair follicle. Sebaceous gland carcinoma commonly arises in the periorbital area. Surgical resection is the most commonly implemented treatment modality in MATs.
Adrenal Myelolipoma: Case Report
Authors: Benaich Dounia , Hsain Ihssan Hadj , Jahid A. , Zouaidia F. , Znati K. , Bernoussi Z.
Published: February 2024

Introduction: Myelolipomas were first described in 1905 as an adrenal tumor composed of mature fat mixed with myeloid and erythroid cells. Adrenal myelolipomas are the second most common benign type of tumor in the adrenals, following after adrenocortical adenomas. It is mostly discovered incidentally on imaging of abdomen done for non-adrenal related reasons or at autopsy. Symptomatic tumors, growing tumors or tumors larger than 10 cm should be excised surgically. We report the case of 1 male patient presenting with flank pain and upper pole renal masse, treated surgically with adrenalectomy. Myelolipoma was confirmed on histology. Case presentation: a 46-years-old male, with a history of blood hypertension, presented with persistent abdominal discomfort and occasional pain in the right flank region. Physical examination revealed a non-tender palpable mass in the right upper quadrant of the abdomen. The abdominal CT scan revealed a large well-defined retroperitoneal tumor, which compressed and displaced the right kidney downward, the mass was heterogeneous with areas of soft-tissue attenuation. The patient underwent open left adrenalectomy. The pathological study confirmed the diagnosis of adrenal myelolipoma. The differential diagnosis of fat-containing retroperitoneal masses would include retroperitoneal lipoma or liposarcoma and renal angiomyolipoma. Discussion: Adrenal myelolipomas are the second most common adrenal incidentalomas comprising 6 to 16% of adrenal incidentalomas. The size of adrenal myelolipomas is variable and can range from a few millimeters to greater than 10 cm. These are called giant adrenal myelolipomas. The largest adrenal myelolipoma reported to date weighed 6 kg. Extra-adrenal sites for myelolipomas include the retroperitoneum, thorax, and pelvis. Usually unilateral however they can also involve both adrenals. The most common symptoms observed are abdominal discomfort/pain, hypochondrial pain, and flank pain. Ultrasonography (USG), ......
Tuberculous Tenosynovitis of the Wrist: A Case Report
Authors: Y Bouras, , M Elkaseh, , A Achkoun, , S Aziz, , A Benhima, , I Abkari,
Published: February 2024

Tuberculous tenosynovitis is a rare localization of tuberculosis. Diagnosis is often delayed due to poor and chronic clinical manifestations. We report a case of tuberculous tenosynovitis of the left wrist with a favourable evolution under antituberculosis treatment.
Profile of Health Status in Relation to Working Pattern and Habits among Street Vendors in Bangalore City
Authors: Prasad K N , Puttaswamy Mr M , M Maheshwari
Published: February 2024

Introduction: Street vendors are important informal self-employment group in the community and their health, nutritional and security status are affected because of weather conditions, pollution in urban area, mental stress and working hours. There is a lack of studies on health profile in street vendors in big cities. This study was conducted with as objective to know the socio demographic profile, health status in relation to their working pattern and habits among the street vendors. Material and Methods: This is a cross sectional and descriptive study. The data was collected by direct interviewing the subjects in their own language at their workplace in Bangalore city using pre tested semi open ended questionnaire. Sample size was determined based on the pilot study. The data included socio demographic, type of business, earning, working years, preexisting health status, body weight and height, habits etc. Subjects who were doing service or selling on mobile carts but not at fixed point and street vendors serving ready to eat foods were excluded. Body Mass Index was estimated as anthropometric nutritional status assessment. Data was analysed in SPSS software version. Results: The study subjects were 275 in the age group of 20 to 70 years and males accounted for 62.5 percentage. The proportion of subjects in the age of 41 years and above was 52.3%. Majority did not have formal schooling and common business was fruits and vegetables selling. Their working hours varying from 4 to 10, and doing business since 2 to 30 years with median of 20 years. The habit of smoking, tobacco chewing and alcohol was present in 30.2%, 14.5% and 14.2% the total. Overweight and obesity accounted for 78.9 % among the total where 19.8% and 25.2% were obese in males and females. The overall prevalence of Hypertension, Diabetes Mellitus and other conditions were 30.5%, 23.6% and 7.2% irrespective of their age, sex, type of business, working hours and habits. The prevalence ........
An Unusual Presentation of Partial Atrioventricular Canal Defect in an Elderly Woman
Authors: Beladel Wassim , Minaoui Mohamed El
Published: February 2024

A partial atrioventricular canal defect (PAVCD) is a form of endocardial cushion defect. It’s a rare congenital cardiac malformation, few reported patients have survived into the seventh decade of life. A 71-year-old female with a history of diabetes and hypertension was admitted for heart failure (HF) symptoms. Transthoracic echocardiography revealed a left to right shunt in the basal portion of the interatrial septum, 19mm ostium primum atrial septal defect (ASD), a mitral valve cleft, and severe mitral valve regurgitation. PAVCD consists of an ostium primum ASD and the dividing of the common atrioventricular (AV) valve into 2 separate AV orifices, resulting in a so-called cleft in the mitral valve. The ventricular septum is intact. Echocardiography is the key tool for diagnosis and anatomic classification. Surgical repair is recommended in adults with primum ASDs causing impaired functional capacity, right atrial or right ventricular enlargement, and left-to-right shunt without cyanosis, as long as systolic pulmonary artery pressures are lower than 50% of systemic pressures. Reconstructive surgery includes, in addition to the closure of the interatrial septum, a suturing of the mitral cleft. The estimated mean age at death of the patients with ostium primum ASD is about 40 years. The objective of this clinical case is to highlight the good clinical tolerance of atrial shunts and the anatomical particularities in the PAVCD.
Thermal and Structural Modelling of Laboratory-Scale Pyrolysis Reactor
Authors: A Akinsade, , O Akinola, A. , S Yaru, S. , F Eiche, J.
Published: February 2024

This paper presents the steady-state thermal and static structural modelling of a laboratory-scale pyrolysis reactor for the thermal degradation of biomass wastes. A laboratory-scale pyrolysis reactor of volume 9.203 x 10-3m3 was developed to pyrolyse Palm Kernel Shell (PKS) and Palm Fruit Bunch (PFB) at varying temperatures of 350oC, 400oC, 450oC, 500oC, and 550oC. The reactor chamber was simulated for static-steady thermal and static structural analysis to determine the temperature distribution and thermal stresses induced in it. The model was developed using SolidWorks software, and a Computational Fluid Dynamics (CFD) simulation was carried out using ANSYS Workbench 19. A total number of 2,459 elements was generated composed of 8630 nodes using Hexahedra dominant meshing method. It was observed from the simulation result that the temperature distribution inside and outside the reactor chamber were 454.29oC and 550oC respectively. The maximum heat flux of 8.3466e+005 W/m² occurred at the inner chamber of the reactor due to the high concentration of the biomass waste and devolatization reaction, and the maximum equivalent (von-Mises) stresses the material can withstand at higher temperature is 1.6674e+009 Pa without rupture. It was found out from the simulation result that at a maximum temperature of 550oC, the equivalent (von Mises) stresses induced at the outer and inner chamber is 1.8585e+008 Pa, which is far lower than the maximum stress the material can withstand without rupture. Thus, the reactor is safe to operate at a temperature higher than 550oC without failure.
POTENSI ANTIINFLAMASI EKSTRAK BATANG WUNDU WATU (Alpinia monopleura) TANAMAN ENDEMIK ASAL SULAWESI TENGGARA SECARA IN VITRO
Authors:   Program Studi D-III Farmasi, Politeknik Bina Husada Kendari, Musdalipah Musdalipah , Tee Selfyana Austin , Yodha Agung Wibawa Mahatva , Reymon Reymon , Setiawan Muh. Azdar , Karmilah Karmilah , Oktaviani Santi
Published: February 2024

The wundu watu plant (Alpinia monopleura), is one of the endemic plants typical of Southeast Sulawesi which is commonly found in South Konawe Regency. The results of previous research on the essential oil content of the leaves and fruit of wundu watu are Î±-caryophyllene, Î²-pinene, limonene, Î±-pinene, Î²-caryophyllene and caryophyllene oxide. The essential oils of the leaves and fruit show antibacterial, antioxidant and anti-inflammatory properties. Pharmacological studies of this plant are not widely known, especially its efficacy as an anti-inflammatory. The purpose of this study was to determine the anti-inflammatory potential of extracts and fractions of wundu watu stem against inhibition of protein denaturation in Vitro. Wundu watu stem extract was extracted by maceration method using methanol solvent and ethyl acetate fraction. Anti-inflammatory testing using the protein denaturation inhibitor method using bovine and albumin and measured on a UV-Vis Spectrophotometer at a wavelength of 660 nm. The results showed that the extract and ethyl acetate fraction of wundu watu stem had anti-inflammatory activity with IC50 values of 10.59 mg/L and 2.02 mg/L. Based on the test results, it can be concluded that the stem extract of wundu watu has anti-inflammatory potential against protein denaturation with a very strong category.
INFLUÊNCIA DOS ÓLEOS ESSENCIAIS NA MELHORIA DO SONO: UMA REVISÃO CIENTÍFICA
Authors: Silva Thainara Pereira da , Cunha Ítalo íris Boiba Rodrigues da , Lima Jefferson  Raimundo de Almeida , Figueiredo Kaísa Lindomara dos Santos , Chaves Fabiola Gondim Medeiros , Souza Thaiana de , Alencar Itiel Elanã Soares , Silveira Maitê Bonfim Nogueira , Junior Sandoval Fernando Cardoso de Freitas , Freitas Sara Regina Moura de , Mendes Pedro Afonso Ribeiro , Mendonça Lívia Cruz de
Published: February 2024

A qualidade do sono desempenha um papel fundamental na promoção da saúde e do bem-estar. Neste artigo, exploraremos a fascinante influência dos óleos essenciais na melhoria do sono. À medida que buscamos abordar as propriedades relaxantes e terapêuticas desses óleos, examinaremos como sua aplicação pode ser uma estratégia eficaz para otimizar a qualidade do sono e proporcionar benefícios para o corpo e a mente. Objetivos; Analisar a melhora do sono, por meio dos óleos essenciais. Metodologia: A pesquisa foi realizada através do acesso online nas bases de Scientific Electronic Library Online (SCIELO), PubMed, Literatura Latino-Americana do Caribe em Ciências da Saúde (LILACS), no mês de janeiro de 2024. Foi realizada a interpretação analítica dos artigos com a temática Aromaterapia e óleos essenciais e sua relação a qualidade do sono, mediante a leitura os artigos foram submetidos a critérios de inclusão e de exclusão, dentro os de inclusão foram considerados artigos originais, que abordassem o tema e permitissem acesso integral ao conteúdo do estudo, publicados no período de 2015 a 2023, em português e em inglês. O critério de exclusão foi imposto naqueles trabalhos que não estavam nesses idiomas, e que não se relacionassem com o objetivo do estudo. Assim, totalizaram-se 31 artigos científicos para a revisão narrativa da literatura. Resultados e Discussões:  Determinados óleos essenciais, lavanda e camomila, têm demonstrado potencial significativo na redução da insônia e na promoção de um sono mais profundo. A interação desses compostos com receptores no sistema nervoso central parece desempenhar um papel crucial com os seus efeitos benéficos, de forma a considerar os mecanismos subjacentes a esses efeitos. A aromaterapia, ao inalar os óleos essenciais, pode influenciar o sistema límbico, regulando a atividade cerebral associada às emoções e ao sono. Além disso, a liberação de certos compostos durante a inalação pode impactar os neurotransmissores, como a serotonina, que desempenham um papel na regulação do sono. Conclusão: Em suma, os óleos essenciais, notadamente a lavanda, demonstra promissor potencial na melhoria da qualidade do sono. Embora os resultados sejam encorajadores, é essencial continuar pesquisando para validar consistentemente esses efeitos e compreender completamente os mecanismos subjacentes. A individualidade na resposta aos óleos essenciais destaca a importância de abordagens personalizadas. Diante disso, considerando o impacto positivo observado, a inclusão cuidadosa desses recursos naturais pode oferecer uma opção complementar valiosa para aqueles que buscam aprimorar seu sono de maneira natural.
ABORDAGENS TERAPÊUTICAS NA PREVENÇÃO DA PROGRESSÃO DA DOENÇA DE ALZHEIMER: UMA REVISÃO SISTEMÁTICA E META-ANÁLISE
Authors: Oliveira Gabriela Cruz de , Bessa Nathalia Sbampato Mol , Haddad Lucas Oliveira Dabien , Assunção Cleaide Ataíde Lima , Assuncao Júnior José Lima , Albuquerque Áurea Amélia Coutinho Nogueira de , Paysano Maria Lúcia Brito de Araujo , Gouveia Pietro Brandão , Cruz Juliana Gomes , Cavalcante Rômulo Basílio Ferro Gomes , Coímbra Igor Bonifácio Andrade , Rapette Fiama Jéssica Francieli Cardoso , Morais Júlia Rodna Gomes Paiva Arcanjo de , Martins Vitoria Roriz , Neves Sara Izabel Cargnin Henrique , Ferreira Laís Jaciara Costa Revil , Ramos Isabela Costa , Miguez Juliana Pinho , Cerqueira jr Vanilson Pires , Barbosa Matheus Fonseca , Vieira Izadora Carneiro , Reis Davi Bayma , Pereira Narjara Samya Rodrigues , Giácomo Brenda Santana Araujo , Fé Filho Rogério Lopes de Moura
Published: February 2024

A abordagem terapêutica na DA está em constante evolução, abrangendo desde avanços farmacológicos até estratégias inovadoras que visam aprimorar a neuroplasticidade. Essa diversidade de opções terapêuticas reflete um esforço contínuo para oferecer tratamentos mais eficazes e abrangentes para os afetados pela DA, destacando a importância do desenvolvimento contínuo de estratégias terapêuticas nesse cenário desafiador. Trata-se de um estudo cujo objetivo foi identificar abordagens terapêuticas destinadas à prevenção da progressão da doença de Alzheimer. Nesse sentido, foi desenvolvida uma revisão sistemática da literatura, utilizando as bases de dados Scielo, Lilacs e Medline. Como conclusão, tem-se que as abordagens terapêuticas para a doença de Alzheimer são diversas e em constante evolução. Embora haja avanços promissores, especialmente em estratégias farmacológicas como o uso de anticorpos monoclonais, terapia genética e nanotecnologia, desafios persistem, incluindo a variação na eficácia de tratamentos específicos e a necessidade contínua de avaliação de potenciais efeitos adversos a longo prazo.
ANALYSIS OF DREAMS IN THE NOVELS OF F.M. DOSTOEVSKY AND G. IBRAGIMOV
Authors: Шамсутдинова Р.Г.
Published: February 2024

Изображение бессознательного и различные формы его выявления – это черты, принадлежащие творчеству писателей разных национальных литератур.Бессознательное как сфера художественного изображения определяет особенности тематики, проблематики и пафоса произведений, отражает авторскую концепцию личности, представления писателя о сущности тех или иных психологических состояний, процессов. Сон является одной из форм бессознательного. У всех снов есть одна общая функция: они являются доказательством того, что личность находится в разногласии с бессознательным. Исследование снов, предшествующих им психологических состояний героев и последующих событий позволяет раскрыть характер соотношения двух сфер – сознательного и бессознательного. Поставленные задачи определили необходимость обращения к сопоставительному анализу фрагментов романоврусского и татарского писателей, в ходе которого дается характеристика психологическому подтексту снов героев и описанию соотношение сна и яви в сопоставляемых произведениях. В бессознательном состоянии сна герои постигают законы мироздания и вселенной, тайны жизни и смерти. Сны в сопоставляемых произведениях выполняют сходные функции: являются средством самоуглубления и самоанализа; откликом на непосредственные впечатления; способом психологической индивидуализации характеров; имеют сюжетообразующее значение, приобретают символический смысл и др.
REPRESENTATION AND CONTENT OF THE CONCEPT WATERIN FOLKLORE (ON THE MATERIAL OF RUSSIAN FOLK TALES BY A.N. AFANASYEV)
Authors: Чжан Ц.
Published: February 2024

В статье рассматриваются особенности языковой репрезентации и содержание концепта вода в русских народных сказках. Определена макроструктура анализируемого концепта, включающая информационное, образное и интерпретационное содержание. В настоящем исследовании использованы методы концептуального анализа, контекстуального анализа, сплошной выборки. Материалом для исследования послужили 408 контекстов с лексемами вода, море, океан, река, озеро, волна, ключ, отобранные из трехтомника «Народных русских сказок» А.Н. Афанасьева. Новизна исследования в том, что впервые макроструктура концепта вода исследуется и моделируется на материале сказок А.Н. Афанасьева, одном из жанров русского фольклора. Народные сказки, как и пословицы, поговорки, фразеологизмы, – это часть национальной культуры. Однако в сказке лексема «вода» обретает контекст и подтекст в развитии, происходит приращение смысла, невозможное в застывших фольклорных формах. Благодаря особенностям языковой репрезентации обогащается само содержание концепта вода. Исследование проводится в рамках лингвоконцептологии – современного научного направления, возникшего на основе когнитивной лингвистики, классической семантики, функциональной лингвистики, обогащенного знаниями, выработанными всеми гуманитарными науками. В этом смысле наше исследование актуально и может дополнить представление о концепте вода, уже существующее в научных трудах. Кроме того, вода, как одна из четырех стихий, занимает важное место в национальной концептосфере, этим обусловлен интерес исследователей к разным аспектам концепта вода. Исследование макроструктуры концепта вода на материале «Народных русских сказок» А.Н. Афанасьева выявило ведущую роль интерпретационного поля данного концепта. Верифицировать сделанный вывод позволяют приведенные в статье контексты. Следует, однако, подчеркнуть, что эти данные получены, пусть и на обширном, но тематически и жанрово ограниченном материале. Научная объективность требует исследования макроструктуры концепта вода на материале текстов разных жанров и стилей.
THE IMAGE OF A WOMAN IN THE ARAB AND RUSSIAN NATIONAL PICTURES OF THE WORLD (BASED ON THE MATERIAL OF PAREMIOLOGY)
Authors: Попова Ю.С. , Сулемина О.В.
Published: February 2024

В работе производится анализ пословиц на русском и арабском языке с точки зрения совпадения/несовпадения традиционных гендерных представлений о женщине в языковой картине мира. На примере толкования пословиц выделяются оценочные и эмоциональные компоненты значения путем выстраивания бинарных оппозиций: зависимость – равность, коварность – скромность, властность - мягкость/ безволие/ бесправие. В результате исследования выделяется ряд общих качеств и характеристик, присущих женщине в обеих языковых картинах. Ее зависимое положение от статуса, который свидетельствует о принадлежности к семье (отзеркаливание положения мужчины). Или принадлежности к роду родителей, если женщина не замужем. Перемены в жизненном пути влекут перемены в наименовании и дальнейшей судьбе (девка/девушка-баба/женщина). Отмечаются и различия в представлении о женщине. В оппозиции коварство-скромность, второе качество является благодетелью общечеловеческой, не разделенной по гендерному признаку. Также в арабской языковой картине используются образы-маски, которые являются сосредоточением определенного качества. Эти завуалированные символы раскрываются в образах животных. Женщины сравниваются с хищницами. При этом традиционное представление о хищных животных в русском сознании и арабском различается. Одно и то же качество характера в зависимости от ситуации может быть отмечено как положительной характеристикой, так и негативной. Мягкость, например, с одной стороны, является синонимом доброты, а с другой стороны, не подлинное, показное проявление этого качества является обманом и подлежит порицанию. Отмечается уникальный, самобытный взгляд на женщину, отражением которого является паремийный пласт языка. Выделяются и общеуниверсальные характеристики, представляющие образ женщины с точки зрения общечеловеческих ценностей, не подлежащих изменениям многими столетиями.
TEXT MARKERS OF E. NEKRASOVA'S IDIOSTYLE
Authors: Подтележникова Е.Н. , Луценко А.Ю.
Published: February 2024

В статье проведен анализ текстовых маркеров идиостиля Евгении Некрасовой, современной российской писательницы, проза которой ещё не становилась объектом лингвистического исследования. Принадлежность к литературе постмодернизма во многом обусловливает специфику структуры и содержания рассказов Е. Некрасовой, которые отличаются эклектичностью, магическим реализмом, нарушением устоявшихся норм художественного повествования, что, несомненно, привлекает читателя. Однако за кажущейся развлекательностью скрывается непринятие автором современной модели поведения и осуждение «из души шагнувших». К основным текстовым маркерам идиостиля Е. Некрасовой были отнесены стилистические (метафора, сравнение, олицетворение, перифраза, каламбур) и лексико-синтаксические (повторы). Характерной особенностью метафор является использование ментефактов в качестве сферы-аттрактора. Кроме того, для создания фантастических образов Е. Некрасова часто прибегает к приему буквализации метафоры, которая является не только способом создания художественного образа, но и особым сюжетным ходом, вызывающим недоумение читателя и создающим эффект ирреальности. Олицетворения Е. Некрасовой превращают обычные вещи в фантастических существ. К «стилистическому ядру» идиостиля писательницы наряду с метафорами также могут быть отнесены сравнения, в которых ярко проявляется авторское словотворчество, обладающее максимальной степенью окказиональности и требующее для расшифровки «настройки на волну автора». Каламбуры Е. Некрасовой не только выполняют функцию комичности, но и служат единой цели, ощутимо проявляющейся во всем творчестве автора – описанию и скрытому осуждению аморального поведения, нарушения этических норм. Перифраза чаще всего служит средством выражения иронии. Основными лексико-синтаксическими текстовыми маркерами в прозе Е. Некрасовой являются повторы, которые создают смысловую целостность художественного текста и обращают внимание читателя на самое главное. Высокая частность и использование повторов всех уровней языка говорит о несомненной значимости данного изобразительного средства для Е. Некрасовой.
ASPECTS OF STUDYING OF BIBLIONYMS
Authors: Устинова Н.Н.
Published: February 2024

В статье уделяется внимание системному изучению библионимов как одному из важнейших компонентов художественного произведения. Исследование в этом направлении актуально и значимо, поскольку название текста тесно связано с его содержанием, а значит, способно раскрыть его лучше читателю. Приводятся примеры названий книг ранних текстов, когда заголовков в привычном представлении вовсе не было. Рассматриваются произошедшие метаморфозы с названиями, как они появились и как исчезали или менялись с течением времени. Эти названия сравниваются с названиями текстов авторов ХХ века, в частности, с названиями иронических детективов Дарьи Донцовой. Сами авторы к выбору библионима относятся по-разному, это надо учитывать при изучении вопроса о влиянии названия на содержание. Также затрагивается вопрос о целесообразности версии прямого влияния названия художественного текста на его содержание. Оно может указывать на систему образов или на одного персонажа, может описывать сюжет, содержать парадоксы, может указывать на внутреннее состояние героя. В статье рассматриваются структурные изменения заголовков, произошедшие в ходе развития литературы, отмечаются многоплановость и многофункциональность названий произведений, возможность формирования сложного знакового комплекса, встроенную в текст программу интерпретации. Также предлагается подходить к семантике названия текста с разных позиций. Можно делать определенные выводы на этапе знакомства с названием, можно позже, в процессе работы над текстом, а можно осмыслить заголовок уже после прочтения. В любом случае, выбор заголовка требует от автора текста мастерства, а от читателя умения правильно его интерпретировать.
Phytonymic code in V.A. Soloukhin’s lyrics (by the example of flower plants)
Authors: Сухова К.И.
Published: February 2024

Проблемы лингвокультурологии являются актуальными для современной филологической науки. Языковая картина мира каждого автора отличается своими специфическими чертами, в связи с чем представляет интерес для лингвиста. Несмотря на многочисленность публикаций по этой проблематике, практически отсутствуют системные исследования творчества В.А. Солоухина. В данной статье рассматривается фитонимический код стихотворных текстов В.А. Солоухина, а именно, лексико-семантическая группа «Наименования цветочных растений», включающая как дикорастущие, так и культурные породы, доминантами которых являются ромашка, василек, одуванчик, роза. Это обусловлено связью творчества поэта с культурой, духовным миром русского этноса, в сознании которого отражены представления и знания народа об этих цветах, особенности их эстетического и эмотивного восприятия, индивидуально-авторские предпочтения. Отмечается, что номинации дикорастущих цветов, таких как ромашка, василек, одуванчик активно функционируют в лирике В.А. Солоухина, соотносясь с понятием любви. Наиболее поэтизирована В.А. Солоухиным из культурных цветочных растений роза – в современном восприятии царица цветов. Частое введение в текст стихотворений данной фитолексемы связано с именем жены писателя. Тем не менее, появление данного образа в поэтической картине мира В.А. Солоухина – это не только, отсылка к имени жены, но и продолжение литературной традиции как Золотого, так и Серебряного веков. Полученные результаты вносят вклад в изучение творчества писателей-деревенщиков, что, несомненно, важно при проведении лингвокультурологических исследований, направленных на изучение не только национальной, но и индивидуально-авторской картины мира.
Analisa Peran Kelembagaan Petani Terhadap Adopsi Sistem Pertanian Organik
Authors: Suswadi  , Nadian Nur Aulia  , Agung Prasetyo
Published: February 2024

The purpose of this study is to analyze the role of farmer groups in the adoption of organic farming system innovations. The location of this research was carried out in the Argoayuningtani farmer group, Selo Boyolali. The research method used is descriptive quantitative and data analysis methods use the correlation coefficient

The results of the data analysis obtained that the Learning Class Variable obtained an average Likert Scale of 4.29 (good), the Cooperation Vehicles Variable obtained an average of 4 (good), the Production Unit Variable obtained an average of 4.3 (good) and The Innovation Adoption Variable obtained an average Likert scale of 4.46 The significant value of the learning class variable is 0.000  ? 0.05. The learning class variable is 0.000 < ? 0.05 which shows that there is a relationship between the role of farmer group production units on the adoption of organic farming system innovations. The R Square Determination Coefficient value is 0.965 or 96.5%, the effect of the role of the group on the adoption of organic farming system innovations, 3.5% is explained by other variables outside the learning class variables, collaboration vehicles and production units (good).