bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of different fluid management on lung and kidney during pressure‐controlled and pressure‐support ventilation in experimental acute lung injury
Authors: de Carvalho Eduardo Butturini , Fonseca Ana Carolina Fernandes , Magalhães Raquel Ferreira , Pinto Eliete Ferreira , Samary Cynthia dos Santos , Antunes Mariana Alves , Baldavira Camila Machado , da Silveira Lizandre Keren Ramos , Teodoro Walcy Rosolia , de Abreu Marcelo Gama , Capelozzi Vera Luiza , Felix Nathane Santanna , Pelosi Paolo , Rocco Patrícia Rieken Macêdo , Silva Pedro Leme
Published: September 2022

Optimal fluid management is critical during mechanical ventilation to mitigate lung damage. Under normovolemia and protective ventilation, pulmonary tensile stress during pressure‐support ventilation (PSV) results in comparable lung protection to compressive stress during pressure‐controlled ventilation (PCV) in experimental acute lung injury (ALI). It is not yet known whether tensile stress can lead to comparable protection to compressive stress in ALI under a liberal fluid strategy (LF). A conservative fluid strategy (CF) was compared with LF during PSV and PCV on lungs and kidneys in an established model of ALI. Twenty‐eight male Wistar rats received endotoxin intratracheally. After 24 h, they were treated with CF (minimum volume of Ringer's lactate to maintain normovolemia and mean arterial pressure ≥70 mmHg) or LF (~4 times higher than CF) combined with PSV or PCV (VT = 6 ml/kg, PEEP = 3 cmH2O) for 1 h. Nonventilated animals (n = 4) were used for molecular biology analyses. CF‐PSV compared with LF‐PSV: (1) decreased the diffuse alveolar damage score (10 [7.8–12] vs. 25 [23–31.5], p = 0.006), mainly due to edema in axial and alveolar parenchyma; (2) increased birefringence for occludin and claudin‐4 in lung tissue and expression of zonula‐occludens‐1 and metalloproteinase‐9 in lung. LF compared with CF reduced neutrophil gelatinase‐associated lipocalin and interleukin‐6 expression in the kidneys in PSV and PCV. In conclusion, CF compared with LF combined with PSV yielded less lung epithelial cell damage in the current model of ALI. However, LF compared with CF resulted in less kidney injury markers, regardless of the ventilatory strategy.
On the local behavior of local weak solutions to some singular anisotropic elliptic equations
Authors: Ciani Simone , Skrypnik Igor I. , Vespri Vincenzo
Published: September 2022

We study the local behavior of bounded local weak solutions to a class of anisotropic singular equations of the kind

∑

i
=
1

s

∂

i
i

u
+

∑

i
=
s
+
1

N

∂

i

(

A

i

(

x
,
u
,

∇

u

)

)

=
0
,

x
∈
Ω
⊂

⊂

R

N

for

1
≤
s
≤

(

N
−
1

)

,

\mathop{\sum }\limits_{i=1}^{s}{\partial }_{ii}u+\mathop{\sum }\limits_{i=s+1}^{N}{\partial }_{i}({A}_{i}\left(x,u,\nabla u))=0,\hspace{1.0em}x\in \Omega \subset \hspace{-0.3em}\subset \hspace{0.33em}{{\mathbb{R}}}^{N}\hspace{1.0em}\hspace{0.1em}\text{for}\hspace{0.1em}\hspace{0.33em}1\le s\le \left(N-1),

where each operator

A

i

{A}_{i}

behaves directionally as the singular

p

p

-Laplacian,

1
<
p
<
2

1\lt p\lt 2

. Throughout a parabolic approach to expansion of positivity we obtain the interior Hölder continuity and some integral and pointwise Harnack inequalities.
Experimental study on the influence of fuel-rich and fuel-lean coal/airflow ratio on aerodynamic characteristics of a 300MWe foster wheeler down-fired boiler
Authors: Du He , Li Zhengqi , Zhang Mingdi , Zhang Ning , Chen Zhichao , Song Jian , Fang Fan , Su Jianjun , Liu Haibing
Published: September 2022

To address the problem of late ignition and poor burnout of Foster-Wheeler down-fired boilers, this study proposed a new combustion technology, which combines adding on arch secondary air and alternately arranging the fuel-lean coal/airflow (FLCA) and fuel-rich coal/airflow (FRCA). The coal particle trajectories of FLCA and FRCA and overall aerodynamic characteristics in the furnace were studied at FRCA and FLCA ratio (R
RL) of 5:5, 7:3, and 9:1. The results showed that even at a low FRCA ratio, the new combustion technology could still effectively ensure the penetration depth of pulverised coal/airflow. At different R
RL values, the main airflow from the arch appeared in the near-wall area and could penetrate downwards into the cold ash hopper area. With an increase in the value of R
RL, the deflection degree of FLCA towards the furnace wall increased, while that of FRCA decreased. At R
RL of 7:3, both the penetration depth and deflection degree of FRCA and FLCA were at a high level, which was conductive to promoting the burnout and recommended in practical applications.
Relative Valuation of Private Held Companies: Valuation Multiples in the Czech Brewing Industry
Authors: Drábek Michal
Published: September 2022

This article focuses on the topic of the relative valuation from the perspective of non-publicly traded companies and the determination of industry multiples allowing the subsequent application of this approach to specific industries. I chose the Czech brewing industry as the target industry, represented by the 50 most important entities (covering more than 99% of the industry’s turnover). Due to the fact that no market value data are available for this type of company, I first used an income valuation approach – the discounted cash flow (DCF) method to assess the market value of each company in the sample. I then quantified valuation multiples of P/E, EV/EBIT, EV/EBITDA, P/S, EV/S, P/BV, and EV/IC for each company, from which I determined industry statistics. I verified their suitability for use in the relative valuation approach and compared them with the results of existing studies on the most commonly used valuation approaches in the Czech Republic. Furthermore, I compared my own calculations of industry multiples for non-publicly traded companies with available data on industry multiples of publicly-traded companies in the brewing industry across Europe. The results of the comparison show that these multiples are on average lower for non-publicly traded companies than for listed companies.
The effect of materials and curing system on the behavior of self-compacting geopolymer concrete
Authors: Al-Bayati Maan A. , Abdulrahman Mazin B. , Alzeebaree Radhwan , Arbili Mohamed M.
Published: September 2022

The aim of the present work was to investigate and achieve the optimum compressive strength of self-compacting geopolymer concrete (SCGC). Fly ash (FA) and ground granulated blast furnace slag (GGBFS) are used at different ratios as binder materials to produce the SCGC mixes. Alkaline solution was a mix of sodium silicate and sodium hydroxide. Three different ratios of binder materials were used to produce SCGC (0FA-100GGBFS; 50FA-50GGBFS; and 100FA-0GGBFS). The total binder weight was 500 kg/m3 within a constant alkali–binder proportion (0.5). Two curing conditions were used, at ambient environment and heat curing at 110°C for 24 h. The compressive strength and fresh properties of SCGC are evaluated. The compressive strength is utilized to demonstrate the mechanical properties of SCGC. The compressive strength is investigated at two ages (7 and 28 days). The results showed that the use of GGBFS had a negative effect on the fresh properties of SCGC. However, it has a significant impact on the mechanical behavior of the SCGC. SCGC’s early strength is heavily involved in heat curing. The compressive strength of 100% GGBFS in the ambient environment after 28 days was more than that of GGBFS cured at 110°C. The optimum eco-friendly mix is 50FA-50GGBFS.
Treatment and outcomes of mechanical complications of acute myocardial infarction during the Covid-19 era: A comparison with the pre-Covid-19 period. A systematic review and meta-analysis
Authors: Spadaccio Cristiano , Pisani Angelo , Salsano Antonio , Nenna Antonio , Fardman Alexander , D’Alessandro David , Santini Francesco , Gaudino Mario F. L. , Sundt Thoralf M. , Rose David
Published: September 2022

This study aims to compare treatments and outcomes of mechanical complications of acute myocardial infarction (MI) during the Covid-19 and in the pre-Covid-19 era. Electronic databases have been searched for MI mechanical complications during the Covid-19 era and in the previous period from January 1998 to January 2020 (pre-Covid-19 era), until October 2021. To perform a quantitative analysis of non-comparative series, a meta-analysis of proportion has been conducted. Early mortality after surgical treatment was 15.0% while it was significantly higher after conservative treatment (62.4%) (P = 0.026). Early mortality after surgical treatment was seemingly higher in the pre-Covid-19 era but the difference did not reach statistical significance (15.0% vs 38.9%; P = 0.13). Mortality in patients treated conservatively, or turned down for surgery, was lower during the Covid-19 pandemic (62.4% vs 97.7%; P = 0.001). The crude mean prevalence of the use rate of conservative or surgical treatment across the studies during Covid-19 and in the pre-Covid-19 era was comparable. The current increased incidence of MI mechanical complications might be a consequence of delayed presentation or restricted access to hospital facilities. Despite the general negative impact of Covid-19 on cardiac surgery volumes and outcomes and the apparent increase of the incidence of MI complications, the outcomes of their surgical and clinical treatment seem not to have been affected during the pandemic.
Artificial gorilla troops algorithm for the optimization of a fine plate heat exchanger
Authors: Gürses Dildar , Mehta Pranav , Patel Vivek , Sait Sadiq M. , Yildiz Ali Riza
Published: September 2022

Adaptability of the metaheuristic (MH) algorithms in multidisciplinary platforms confirms its significance and effectiveness for the solution of the constraints problems. In this article, one of the imperative thermal system components-plate fin heat exchangers is economically optimized using the novel artificial gorilla troops optimization algorithms (AGTOAs). The cost optimization challenge of the PFHE includes the initial and running cost that needs to be minimized by optimizing several design variables subjecting to critical boundary conditions. To confirm the performance of the AGTOA, the statistical results obtained were compared with nine benchmark MHs algorithms. It was found that AGTO is a robust optimization algorithm because it was able to fetch the best results for the function with 100% of the success rate compared to the rest of the algorithms. Moreover, considering the superior results obtained from the AGTO, it can be applied to numerous applications of the engineering design optimization.
Thermal analysis and performance testing of heavy load truck composite brake linings
Authors: Bayram Emre , Topuz Ahmet
Published: September 2022

One of the most important variables that determine the braking performance of heavy-duty trucks is the high temperature increases in the brake components. In this study, the effects of high temperatures in brake lining compositions were investigated using thermogravimetric analysis (TGA). Furthermore, dynamometer tests and SEM analysis were performed. Three different compositions, which are called standard, fly ash and sisal fiber mixture, were compared with existing commercial heavy-duty truck brake lining. The thermal behavior of samples analyzed in TGA machine compared to the weight losses with increasing temperatures until 900 °C. Dynamometer tests which simulated the real part production and vehicle tests were realized in brake lining supplier. Finally, with the SEM analysis, both normal and worn surfaces were analyzed and reasons for wear surfaces were investigated. The findings suggest that there is a high potential in fly ash mixture to apply in commercial trucks applications which occurs at very high temperatures and is very suitable for environment and cost reduction points.
Non-finite Verb Movement in Romance
Authors: Groothuis Kim A.
Published: September 2022

Since Pollock, Jean-Yves. 1989. Verb movement, universal grammar, and the structure of IP.Linguistic Inquiry20. 365–424, it is well known that Romance finite verbs move into the I-domain. However, the relationship between finiteness and verb movement has not yet been investigated in detail. The aim of the present study is to trace and analyse verb movement in various types of non-finite and semi-finite clauses in Romance, including infinitives with specified subjects, inflected infinitives, bare infinitival clauses, Aux-to-Comp (cf. Rizzi, Luigi. 1982.Issues in Italian syntax. Dordrecht: Foris), past participial clauses, and gerunds. It is shown that all types of Romance non-finite verbs move high, with the exception of French absolute participles and French infinitives. The picture of non-finite movement is thus more uniform than that of finite verb movement (cf. Schifano, Norma. 2018.Verb movement in Romance. A comparative study. Oxford: Oxford University Press). A unified account is proposed: non-finite verbs all need to be anchored to the speech act through a higher clause, which requires them to be in a local relation with the anchoring head Fin (cf. Groothuis, Kim A. 2020.Reflexes of finiteness in Romance. Cambridge: University of Cambridge Unpublished PhD thesis).
Estimation and interpretation of vaccine efficacy in COVID-19 randomized clinical trials
Authors: Michiels Hege , Vandebosch An , Vansteelandt Stijn
Published: September 2022

Objectives

An exceptional effort by the scientific community has led to the development of multiple vaccines against COVID-19. Efficacy estimates for these vaccines have been widely communicated to the general public, but are nonetheless challenging to compare because they are based on phase 3 trials that differ in study design, definition of vaccine efficacy and the handling of cases arising shortly after vaccination. We investigate the impact of these choices on vaccine efficacy estimates, both theoretically and by re-analyzing the Janssen and Pfizer COVID-19 trial data under a uniform protocol. We moreover study the causal interpretation that can be assigned to per-protocol analyses typically performed in vaccine trials. Finally, we propose alternative estimands to measure the intrinsic vaccine efficacy in settings with delayed immune response.

Methods

The data of the Janssen COVID-19 trials were recreated, based on the published Kaplan-Meier curves. An estimator for the alternative causal estimand was developed using a Structural Distribution Model.

Results

In the data analyses, we observed rather large differences between intention-to-treat and per-protocol effect estimates. In contrast, the causal estimand and the different estimators used for per-protocol effects lead approximately to the same estimates.

Conclusions

In these COVID-10 vaccine trials, per-protocol effects can be interpreted as the number of cases that can be avoided by vaccination, if the vaccine would immediately induce an immune response. However, it is unclear whether this interpretation also holds in other settings.
Retrosplenial and Hippocampal Synchrony during Retrieval of Old Memories in Macaques
Authors: Hussin Ahmed T. , Abbaspoor Saman , Hoffman Kari L.
Published: September 2022

Memory for events from the distant past relies on multiple brain regions, but little is known about the underlying neural dynamics that give rise to such abilities. We recorded neural activity in the hippocampus and retrosplenial cortex of two female rhesus macaques as they visually selected targets in year-old and newly acquired object-scene associations. Whereas hippocampal activity was unchanging with memory age, the retrosplenial cortex responded with greater magnitude alpha oscillations (10–15 Hz) and greater phase locking to memory-guided eye movements during retrieval of old events. A similar old-memory enhancement was observed in the anterior cingulate cortex but in a beta2/gamma band (28–35 Hz). In contrast, remote retrieval was associated with decreased gamma-band synchrony between the hippocampus and each neocortical area. The increasing retrosplenial alpha oscillation and decreasing hippocampocortical synchrony with memory age may signify a shift in frank memory allocation or, alternatively, changes in selection among distributed memory representations in the primate brain.

SIGNIFICANCE STATEMENTMemory depends on multiple brain regions, whose involvement is thought to change with time. Here, we recorded neuronal population activity from the hippocampus and retrosplenial cortex as nonhuman primates searched for objects embedded in scenes. These memoranda were either newly presented or a year old. Remembering old material drove stronger oscillations in the retrosplenial cortex and led to a greater locking of neural activity to search movements. Remembering new material revealed stronger oscillatory synchrony between the hippocampus and retrosplenial cortex. These results suggest that with age, memories may come to rely more exclusively on neocortical oscillations for retrieval and search guidance and less on long-range coupling with the hippocampus.
A Pathway for Regional Integration
Authors: Genna Gaspare M.
Published: September 2022

This article seeks to explain levels of regional integration worldwide. The level of regional integration increases as the economic strength of the regional leader increases under higher levels of satisfaction among partners. The homogenization of domestic institutions also increases under these conditions. Finally, there is a reciprocal effect between integration and the homogenization of domestic institutions. Integration therefore cannot be explained using a single equation but instead requires a system of nonrecursive pathways. The article reviews prior work on regional integration and then contributes to the scholarship by synthesizing the findings of the power-centered and the institutional schools. An analysis of regional integration organizations (1970–2014), using autocorrelation-corrected regressions and structural equation model testing, supports the main hypotheses.
Literacia familiar para crianças com transtorno do espectro autista por meio de um jogo digital educacional
Authors: De Mattos Battistello Viviane Cristina , Petry Justo Vitoria , Volmer Lovani , Lorenz Martins Rosemari
Published: September 2022

A literacia familiar é uma oportunidade de incentivar o hábito de leitura em crianças com autismo, com o envolvimento dos familiares, dos pais, dos professores ou mesmo de alguém da comunidade. Nesse contexto, a presente pesquisa tem por objetivo geral apresentar o relato de experiência do desenvolvimento de um jogo digital educacional, disponível para dispositivos móveis (tablets e celulares) e web, que visa apoiar o processo de mediação da leitura, promovendo a compreensão leitora e a literacia familiar para crianças com autismo. O uso do aplicativo para a contação de histórias apresenta inúmeras contribuições das atividades de interação, de conversa, de leitura em voz alta com as crianças, de maneira a promover e estimular o desenvolvimento da linguagem, com estratégias simples e lúdicas, que proporcionam um envolvimento maior da família na educação das crianças com autismo, de maneira naturalista.
Olga Acosta, John Naranjo y Adalberto Camperos. Delirantes.
Authors: Laurent Muriel
Published: September 2022

La publicación de un cómic académico en el campo de las ciencias sociales y las humanidades debe ser motivo de celebración por su impacto sobre la apropiación social del conocimiento. Como resultado de investigación, Delirantes es una fructífera alianza interdisciplinar entre el mundo académico, la industria editorial y la creación artística: el producto fue ideado por la historiadora del arte Olga Acosta, profesora de la Universidad de los Andes, en compañía del editor John Naranjo, especializado en cómics, y del ilustrador Adalberto Camperos, Electrobudista.
Carlos Uribe Celis. Jesús. La historia alternativa.
Authors: Correa Bermúdez César Leonel
Published: September 2022

Este libro hace una reconstrucción histórica y una interpretación sociológica de la vida, pasión y muerte de Jesús. Por un lado, está basado en fuentes históricas como los evangelios canónicos y apócrifos, las 21 epístolas, los Hechos de los Apóstoles, las narraciones de historiadores antiguos como Flavio Josefo, Filón de Alejandría y Eusebio de Cesarea. Y, por el otro, está basado en el análisis social hermenéutico propuesto por los sociólogos Max Weber, Alfred Schütz y Anthony Giddens. Esto último tiene las siguientes dos implicaciones.
El impacto de la financiación pública-privada en el desarrollo: las experiencias de YPF y Tecpetrol en Vaca Muerta (2014-2020)* Gustavo García Zanotti
Authors: García Zanotti Gustavo
Published: September 2022

En el presente artículo se discutió el impacto de la financiación pública-privada en el desarrollo de los proyectos productivos en la formación no convencional de Vaca Muerta a través de las experiencias que más invirtieron en la misma:  YPF —con Chevron— y Tecpetrol. El sector energético resulta indispensable para el funcionamiento y reproducción del conjunto de la economía. Por esta razón, el Estado se encuentra interesado en su desenvolvimiento. Para ello pretende atraer inversiones privadas a través de estímulos, y al hacerlo contribuye en el financiamiento de este. El sector privado ha invertido a través de préstamos intra-firma desde sociedades relacionadas en el exterior. Sin embargo, la sostenibilidad del financiamiento se dirimirá en términos de la disponibilidad de divisas que este refleje dado que los países como Argentina poseen una severa restricción externa, así como dificultades para retener el capital. En este sentido, las amortizaciones de dichos préstamos significarán la repatriación de los capitales y presionarán sobre la liquidez de divisas. Además, se trata de un sector que demandará inversiones y financiamiento constantemente para mantenerse activo debido a que su necesidad de fondos se encuentra relacionada a la reducida vida útil que poseen los pozos no convencionales.
Argentina’s external insertion during both Convertibility and Post-convertibility: agro-export specialization and financial dependence
Authors: Montanyà Revuelto Miguel , Bordón-Ojeda Marisa
Published: September 2022

This article contributes to the debate around the meaning and extent of changes to Argentina’s economy between 2002 and 2015 (usually referred to as the “Post-Convertibility” period), in contrast to the policies of 1991-2001 (known as the “Convertibility” period), as these changes may have altered operation of the Argentine economy following the abandonment of both the industrialization of import substitution and IMF adjustment policies. Specifically, this research focuses on external insertion, both commercial and financial. It is concluded that a common element throughout both periods was the persistence of trade specialization based on the primary sector and low value added products, while Argentina’s financial insertion in the world economy was characterized by vulnerability and dependency, subject to the reactions of international commodity prices to changes in geopolitics and the global economy. These factors continue to determine financing conditions for the Argentine economy.
Reflexiones sobre olvidos, negacionismos y revisionismos en la transición colombiana
Authors: Piedrahita-Arcila Irene
Published: September 2022

Las transiciones que ha vivido Colombia desde mediados de la década del 2000, han generado debates políticos y académicos sobre el pasado reciente. Las últimas décadas han estado marcadas por tensiones y discusiones que han cuestionado los sentidos que, como sociedad, damos al pasado y al futuro, las razones de la violencia, y lo que tenemos que hacer para que el conflicto armado no se repita. Esto ha movilizado discusiones profundas acerca de los “nuevos comienzos” que generan las transiciones políticas y los conceptos con los que imaginamos, describimos o pensamos la realidad.
Narrar la verdad. Tensiones entre información, narrativa y verdad en la Comisión para el Esclarecimiento de la Verdad en Colombia
Authors: Velásquez-Yepes Santiago , Zuluaga-Aristizábal Marda
Published: September 2022

El objetivo del artículo fue analizar la relación entre narración e información en el trabajo de la Comisión para el Esclarecimiento de la Verdad, la Convivencia y la No Repetición (CEV) con el fin de problematizar las implicaciones del uso de la narrativa en la construcción de la verdad que está realizando esta institución en Colombia, así como dilucidar cuál es la perspectiva de la verdad en la que se sitúa. Para ello, se analizó el método utilizado por la CEV para recolectar testimonios y luego ingresarlos al Sistema de Información Misional (SIM) señalando sus alcances y límites, así mismo se discutió las declaraciones de la Comisión acerca de las características de su informe final a la luz de los usos de la información y la estrategia narrativa para elaborar la verdad. Se concluyó que las relaciones entre la narración y la información en el trabajo de la CEV reflejan los problemas epistemológicos propios de las ciencias sociales en lo relativo a la tensión entre objetividad y subjetividad y que la validez de sus elaboraciones dependerá, más que de la cantidad de información que ha logrado recopilar, del rigor de la contrastación que hagan entre versiones diversas y otras fuentes. Igualmente, se resaltó la apertura de nuevas posibilidades técnicas y metodológicas para el esclarecimiento de la verdad y el seguimiento a los derechos humanos en Colombia y el mundo que supone el SIM, aunque advirtiendo de las complejidades y dilemas que acarrean los avances en ciencias de la información para el análisis de la realidad social.
La enseñanza del latín para futuros historiadores: una propuesta didáctica basada en la metodología estudio de casos
Authors: Garzón Fontalvo Eveling
Published: September 2022

En el ámbito universitario, la enseñanza del latín no forma parte exclusivamente de los programas en Filología Clásica, sino que también se incluye (generalmente de forma opcional) en otros grados universitarios; este es el caso del grado en Historia. El presente artículo ofrece una propuesta didáctica para adaptar parte de las asignaturas de lengua latina al perfil profesional específico de los alumnos de Historia, utilizando la metodología estudio de casos. Desde este enfoque, se diseñan dos actividades que abordan algunas de las problemáticas que los alumnos pueden encontrarse a la hora de trabajar con fuentes primarias en latín (traducciones y citas). Esta propuesta constituye, en última instancia, el diseño de un proyecto de investigación que tiene por objetivo explorar los alcances de la metodología citada en la enseñanza de las lenguas clásicas.
Fotoramas: Jorge Obando y la fotografía panorámica de los años treinta en Colombia
Authors: Solano-Roa Juanita
Published: September 2022

a partir de los años 30 del siglo XX, el fotógrafo colombiano Jorge Obando empezó a fotografiar utilizando una cámara Cirkut Eastman Kodak. Esta cámara, capaz de rotar 360° grados sobre su eje, le permitió a Obando desarrollar un nuevo tipo de fotografía al producir imágenes en formato panorámico que capturaron el momento de transición hacia la modernidad en Colombia. Este artículo examinó la relación entre el formato de este tipo de fotografías y los temas capturados por Obando. La fotografía panorámica —una evolución del panorama pictórico inventado por el irlandés Robert Barker en 1787— es inseparable de las relaciones de poder establecidas por el medio que nació en el siglo XVIII. De la misma manera, la repetición de los motivos y sujetos capturados por Obando son intrínsecos a la emergente modernidad que se asomaba en Colombia durante los años treinta. El lente de Obando capturó esos momentos de transición mediante una técnica y un formato que reproducen y refuerzan el discurso visual de sus imágenes. A través de un análisis de algunas de sus fotografías, este trabajo hizo evidentes estas relaciones poco exploradas en su obra.
Danzantes del viento/Bínÿbe Oboyejuayëng de Hugo Jamioy como obra-semilla: un acercamiento a algunos procesos colectivos de producción y edición
Authors: Molano Martínez Astrid Paola
Published: September 2022

En este artículo se propone entender el poemario Danzantes del viento/Bínÿbe Oboyejuayëng, del oralitor camëntsa Hugo Jamioy, como una obra-semilla, plena de potencial para germinar y florecer en la interacción con distintas tierras o instancias comunitarias y del campo literario. Con una mirada principalmente externa, se hará un acercamiento a los procesos de creación y edición de Danzantes del viento/Bínÿbe Oboyejuayëng, a través del análisis de entrevistas semiestructuradas realizadas al oralitor, al diseñador de la edición de la Universidad de Caldas y a los editores de la Biblioteca Básica de los Pueblos Indígenas, de la Biblioteca Básica de Cultura Colombiana y de Frailejón Editores. Se concluye que, si bien la figura de Hugo Jamioy como oralitor es fundamental, la comunidad camëntsá y los diversos actores e instituciones del campo editorial son pilares de la construcción del sentido y de la apropiación de Danzantes del viento/Bínÿbe Oboyejuayëng.
Prevalencia de Fasciola hepatica y Paramphistomidae en bovinos de doble propósito en una hacienda del trópico bajo andino colombiano Digeneos en bovinos de doble propósito del trópico bajo andino colombiano
Authors: Arroyo M. I. , Gómez L. , Hernández C. , Agudelo D. , Galván-Diaz A. L. , Velásquez L. E.
Published: September 2022

En muchos países la fasciolosis y paramfistomosis representan un grave problema para la salud del sector pecuario. En Colombia hay registros de ambas distomatosis en bovinos, de la mayoría del trópico alto andino, las cuales generan pérdidas económicas anuales cercanas a 40 000 000 000 COP. El objetivo de esta investigación fue determinar la prevalencia de fasciolosis y paramfistomosis en vacunos de la hacienda La Candelaria, Caucasia (Colombia), y la presencia de caracoles hospederos intermediarios. Para cumplirlo, se realizó un estudio descriptivo de corte transversal con muestreo no probabilístico por conveniencia. Se recolectaron heces de los animales y se hizo el diagnóstico mediante la técnica modificada de Dennis. Se establecieron las prevalencias de los digeneos de acuerdo con el sexo, peso, edad y raza. Se recolectaron caracoles dulciacuícolas en la zona estudiada y se identificaron por morfología. Se analizaron 466 muestras fecales de 178 bovinos, de las razas Cebú (Bos indicus), BON (blanco orejinegro) y del cruce entre ellas. Se diagnosticaron F. hepatica y Paramphistomidae con prevalencias del 2,2% y 30,9%, respectivamente. En el 1,1% de los vacunos se diagnosticó coinfección. Ambas trematodosis prevalecieron en las hembras (p = 0,03). Se identificaron moluscos dulciacuícolas Ampullariidae, Physidae y Planorbidae sin estadios larvarios de digeneos. Se concluyó que los bovinos de doble propósito de la hacienda La Candelaria están expuestos a F. hepatica y Paramphistomidae, y, probablemente, se infectan en los predios de la hacienda. Paramphistomidae es más prevalente que F. hepatica, lo cual concuerda con lo descrito en algunos estudios
Medición de los niveles de lactato sérico y frecuencia cardiaca en caninos (Canis lupus familiaris) braquicefálicos, mesocefálicos y dolicocefálicos sometidos a prueba de esfuerzo en trotadora motorizada
Authors: Saldivia-Paredes M. A.
Published: September 2022

Se analizaron los niveles de lactato sérico y de frecuencia cardiaca (FC) en 15 perros clínicamente sanos que fueron sometidos a pruebas de esfuerzo en trotadora motorizada, buscando verificar un grado de fatiga muscular frente a una prueba de esfuerzo intenso. Se consideraron pacientes con morfología craneana de tipo braquicefálico, mesocefálico y dolicocefálico. Las mediciones séricas de lactato fueron conseguidas por medio de un medidor portátil, mientras que las frecuencias cardiacas se obtuvieron a través de un oxímetro portátil a los tiempos 0, 10, 20 y 30 minutos, en los diferentes momentos de esfuerzo físico en la trotadora motorizada, la cual fue adaptada en su inclinación en 15% y a un máximo de velocidad de 10 km/h. Las medias de los niveles séricos entre perros mesocefálicos y dolicocefálicos fueron significativas, a diferencia de los perros braquicefálicos los cuales resultaron no significativos. Las medias de frecuencias cardiacas no tuvieron diferencia significativa
Ungarische Reisende über europäische Bibliotheken im 16. und 17. Jahrhundert
Authors: Monok István
Published: September 2022

When one examines the descriptions of Hungarian travellers of the 16th–17th centuries, it can be stated that the young people – as the listed examples all bring to life the journeys of young people – were prepared for the trips. These young travellers were also accompanied by teachers, and they could read about the geography and people of the area to be visited in the libraries at home. It is also important that eruditive knowledge, complemented by the experience of the trip, reinforces the knowledge read. They also knew the importance of book publishing and the book trade, and we could cite more passages in this regard than in the case of libraries. The libraries they saw were admired, but usually left unmentioned. They must have visited the university library, yet we can hardly find any information about this in the letters and diaries sent to patrons and parents. In our study, we present and cite some examples, but we mention cases where the traveller also noticed the decoration of the library – paintings, sculptures – and furnishings. Globes are mentioned more often. At the end of the study, I mention that from the end of the 17th century we know of a university debate (dissertation) about libraries. Under the leadership of praesens Johann Georg Zihn, Adam Gruber, a citizen of Sopron, defended his thesis, Disputatio de bibliothecis (Leipzig, 1678). It is also the first library science work by an author from Hungary.
Krleža’s Political and Psychotic Bestiary: An Example of Dramatic Menagerie on a Timeline from 1913/1914 to 1970
Authors: Marjanić Suzana
Published: September 2022

The paper interprets M. Krleža’s political and psychotic bestiary on the example of his plays, beginning with the first fragmental drama Saloma, which opens Krleža’s diary entries (dated 26 February 1914) from the First World War (this is his diary-memoir book Davni dani, subsequently published in 1956), and ends with the screenplay Put u raj (1970), by which Krleža completed his drama work. Focusing on that period (1914– 1970), the paper considers Krleža’s dominant zoo-metaphors in the framework of his negative anthropology. In Saloma, for instance, the zoo-lexeme dog is reflected as the dominant zoo-metaphor. Specifically, for Saloma, everything that happens on war-like Earth is determined by the dog’s existence as a subservient ingratiator toward all forms of power in the government. Instead of O. Wilde’s somewhat precious Secessionist ornamental language, Krleža’s Saloma begins with her aggressive nihilism and with Kyon-metaphors: “Nothing! You are as boring as wet dogs!” (Davni dani, diary entry dated 26 February 1914). This paper identifies Krleža’s dramatic political and psychotic bestiary on select examples (one play per dramatic period), taking into account the classification of Krleža’s dramatic work (18 plays) in five stylistic-generic cycles as part of Krleža’s negative anthropology.

In the screenplay Put u raj, a cricket as the dominant zoo-metaphor discloses himself by his singing to the drama binomials (the ego and alter ego: Bernardo and Orlando) in the urinal, while they are urinating together (the male urinating topos) following their narcotic bliss. By combining two issues, the subject of meditation on the death from the novel Cvrčak pod vodopadom and the theme of the eternal repetition of Human Stupidity from the Finale (see the book of political essays Deset krvavih godina, 1937), Krleža rounds out his personal view of the global anti-utopia and dystopia in this anti-war requiem play.

We conclude that Krleža’s political and psychotic bestiary which we have examined on select examples using the drama menagerie on a timeline from 1913/1914 to 1970 is consistent: within the framework of a permanent negative anthropology, Krleža’s preoccupation with documenting the all-powerful human stupidity of the man-ape who, when it learned to fly, bombs other apes, although in speciesist zoo-metaphors, we can say that Krleža does not find utopia in nature “as there is no justice even among flowers”, as the title of one of his ballads states. In short, by negating Feuerbach’s anthropological thesis Man with man – the unity of I and Thou – is God and by promoting the Ape to / as Man’s deputy, as Desmond Morris does with the cover of Naked Ape, Krleža shows that Man is at its core and being (the ontological structure of the human being) is not homo sapiens. Today’s pandemic picture of the world demonstrates all of this, or as Krleža would say in speciesist manner: man is still an ape, or as a non-speciesist statement: man is still man, the bloodiest animal.
CORPO REGULADO: COMPETÊNCIAS SOCIOEMOCIONAIS E SEXUALIDADES (IN)VISÍVEIS NA BASE NACIONAL COMUM CURRICULAR
Authors: Tondin Celso Francisco , Andrade Aline Campolina , Lemos Flávia Cristina Silveira
Published: September 2022

Este ensaio discute a Base Nacional Comum Curricular como dispositivo tanto de aproximação entre a educação e o mercado, evidenciada pela exaltação da noção de competências socioemocionais, quanto de regulação da diferença, demonstrada no apagamento das temáticas de gênero e orientação sexual em seu texto. Transversalizamos aportes da psicologia escolar de perspectiva crítica e dos estudos decoloniais como epistemologias que convergem para contribuir com a (re)construção da educação como direito humano. Dimensionamos a Base como uma coalizão de forças conservadoras (do mercado e da moral) que engendram um mecanismo que representa e sintetiza uma política educacional que expressa as imbricações entre competências socioemocionais e diversidade sexual e de gênero, de modo que, no jogo de falar/calar, mostrar/apagar, as possibilidades de existência são capturadas por lógicas sexistas, machistas, heterocentradas, racistas, capacitistas, homofóbicas, transfóbicas, xenofóbicas. A psicologia em interface com a educação é desafiada a lidar com as disputas e contradições existentes no contexto das atuais investidas neoliberais e ultrarreacionárias sobre a escola e dos movimentos de resistência e criação de modos de existência mais plurais, igualitários e justos, na tarefa de formar sujeitos democráticos e contribuir para a democratização do conhecimento científico, tornando-o potência para as populações marginalizadas.
Extreme Einwirkung durch Schweißrauche und -gase
Authors: Holtstraeter Reinhard
Published: September 2022

Bisher war umstritten, inwieweit es für das Merkmal der „extremen Einwirkung” i. S. d. Berufskrankheit Nr. 4115 entscheidend auf das Vorliegen eingeschränkter Belüftungsverhältnisse ankomme, wie sie beispielsweise in Kellern, Tunneln, Behältern, Tanks, Containern, engen Schiffsräumen oder vergleichbaren räumlichen Verhältnissen mit arbeitshygienisch unzureichenden Vorkehrungen bestehen. Mit der jetzigen Entscheidung klärt das Bundessozialgericht wesentliche Rahmenbedingen für die Begutachtung der BK 4115.
THE CONSTITUTIONALISATION OF LABOUR LAW: NO PLACE FOR A SUPERIOR LABOUR APPEAL COURT IN LABOUR MATTERS (PART 1): BACKGROUND TO SOUTH AFRICAN LABOUR COURTS AND THE CONSTITUTION
Authors: Stefan van Eck
Published: September 2022

This article explores the status of the Labour Appeal Court under South Africa's constitutional democracy. The stages of development of this country's labour laws have coincided with the establishment of new sets of labour dispute resolution fora: firstly, the Industrial Court; secondly, the labour courts under our present constitutional democracy; and thirdly, a yet to be implemented new dispute resolution paradigm under the proposed Superior Courts Bill. The focus of this contribution is on the influence of the provisions of the Constitution on these developments, and the gradual erosion of the exclusive appellate powers of the Labour Appeal Court by the Supreme Court of Appeal, and the Constitutional Court, in the assertion of their power to serve as highest courts in all labour matters.
EMPLOYERS’ LIABILITY FOR STRESS AT WORK DUE TO AN EXCESSIVE WORKLOAD: NEW POINTERS FROM THE UNITED KINGDOM
Authors: Marlize van Jaarsveld
Published: September 2022

Stress-induced illnesses experienced by employees due to excessive workloads are an alarming problem facing employers in the United Kingdom. Not only are stress-induced illnesses a major cause for concern, but these illnesses have moreover been recognised as the second most common work-related ill-health problem in the UK. Workplaces in South Africa are not shielded from the problematic consequences of the work pressures experienced by employees. So far, these problems have mostly been addressed by utilising the provisions of existing legislation. However, despite the existence of legislation in the UK which deals with safety and health issues in employment, a number of employees have successfully claimed damages from their employers by proving breach of contract. In this article, the possibility of South African employers being held contractually liable for stress-induced illnesses based on the excessive workloads of their employees is analysed from a comparative point of view. It is concluded that contractual liability may very well be a reality should the guidelines which emanated from British case law be followed.
GENDER MAINSTREAMING – AN ETHICAL FEMINIST CONSIDERATION
Authors: Karin van Marle
Published: September 2022

In this article I tentatively consider the notion of gender mainstreaming from an ethical feminist perspective. Underlying this is a tension, or paradox, between law's limits and law's potential, law's poetry, poetry's law. A few theoretical arguments come into play. Firstly, the multiple meanings of sex and gender are reconsidered. Thereafter feminist critiques against the notion of one feminist method as well as a feminist jurisprudence are combined with a critical perspective on the institutionalisation of human rights and the politics of law. I recall these arguments to inform my investigation into gender mainstreaming. Two aspects are considered: firstly, in light of the critical perspectives, the preference for gender mainstreaming instead of challenging from the margins; and secondly, how mainstreaming actually takes place. Relying on the notion of ethical feminism and concepts of “asymmetrical reciprocity”, “city life”, the “imaginary domain” and the “community of the ought to be”, I ponder ways of making gender issues noticed beyond and within attempts at mainstreaming.
Türk toplumunda farklı dik yön büyüme paternine sahip iskeletsel Sınıf 1 bireylerde farengeal havayolunun ve hyoid kemik pozisyonunun değerlendirilmesi
Authors: TÜRKER Gökhan , ARIKAN Emin Serhat
Published: September 2022

Amaç: Bu araştırmada, iskeletsel Sınıf 1 ilişkiye sahip bireylerde dik yön büyüme paterninin farengeal havayolu boyutlarına ve hyoid kemik pozisyonuna etkisinin değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem: Bu retrospektif araştırmaya, ANB açısı temel alınarak iskeletsel Sınıf 1 ilişkiye sahip toplam 72 birey (36 kadın, 36 erkek; ortalama yaş: 17.78 ± 1.39 yıl) dahil edildi. Bireyler dik yön büyüme paternine göre; normodiverjan, hipodiverjan ve hiperdiverjan olmak üzere 3 gruba ayrıldı. Lateral sefalometrik radyografiler üzerinde farengeal havayolu ve hyoid kemik pozisyonu ölçümleri, 1 açısal ve 10 lineer ölçüm kullanılarak yapıldı. Verilerin analizinde bağımsız örneklem t-testi ve tek yönlü varyans analizi (ANOVA) kullanılarak grup içi ve gruplar arası farklılıklar değerlendirildi (p<0.05).
Bulgular: Verilerin grup içi karşılaştırmalarında farengeal havayolu boyutlarına ait ölçümlerin cinsiyetler arasında benzer olduğu (p˃0.05) ve tüm gruplarda hyoid kemiğin servikal vertebralara ve mandibular düzleme olan uzaklıklarının kızlarda anlamlı düzeyde daha az olduğu görüldü (p<0.05). Normodiverjan, hipodiverjan ve hiperdiverjan bireylerin farengeal havayolu boyutları ve hyoid kemik pozisyonunda istatistiksel olarak anlamlı farklılıklar olmadığı belirlendi.
Sonuç: Normodiverjan, hipodiverjan ve hiperdiverjan bireylerde farengeal havayolu boyutlarının ve hyoid kemik pozisyonlarının benzer olduğu görüldü. Bununla birlikte, tüm gruplarda erkeklerde hyoid kemiğinin kızlara göre daha aşağıda ve daha önde pozisyonlandığı belirlendi.
The First Fifteen Years of the BRICS
Authors:   University of Toronto, Kirton John , Larionova Marina ,   Russian Presidential Academy of National Economy and Public Administration (RANEPA)
Published: September 2022

At the first BRIC(S) summit in 2009, leaders of the major emerging market countries (Brazil, Russia, India, and China) from different continents committed to build a democratic and transparent economic architecture, support the efforts of the Group of 20 (G20) to reform the international financial institutions, restore growth, and deepen intra-group cooperation. Since then, views expressed in the literature on BRICS (expanded to include South Africa in 2010) have ranged from the harsh dismissal of BRICS as a meaningless investment banker’s acronym to its identification as a new power centre with a profound impact on the global economic order. The authors offer an updated, systematic assessment of BRICS’ evolving institutional dynamics, performance, and contribution to cooperation among its members, and to global governance as a whole. Using qualitative and quantitative methods, they identify the major achievements of each of the BRICS’ 13 annual summits through the three five-year hosting cycles, the leaders’ agreements on 933 collective commitments, and their countries’ compliance with them at a level of 77% overall. Further, they highlight the expansion of the group’s agenda into 34 subjects, the process of building the intra-BRICS institutions with the New Development Bank (NDB) as its hallmark, and its extensive second track networks including Business, Think Tanks and Academic, Trade Unions, Parliamentarian, Youth and Civil BRICS. In its first 15 years, BRICS expanded and sustained its institutional dynamics, depth, and performance despite external and domestic challenges, tensions between the members, and the unprecedented tests of the COVID19 pandemic and the ensuing socio-economic crises since 2020. Established as a dialogue and policy coordination forum, it matured into a transregional governance institution with a comprehensive political-security, socio-economic, and people-to-people agenda. Its dense institutional networks, flexibility, continuity, and foundational principle of moving forward only on issues acceptable to all members were vital factors for BRICS’ resilience and evolution. Although broadening its agenda inhibited deepening cooperation, there was considerable continuity across the annual presidencies. Progress on intra-BRICS cooperation was more tangible than that on international architecture reform, despite the group’s unwavering commitment to an equitable international order. Its consensus-based working methods sometimes constrained the group’s leadership. However, BRICS proved its value as a platform for facilitating its members’ bilateral relations and convergence in approaches, promoting their role in global governance, and advancing a more inclusive, representative, and effective international institutional system.
Light microscopy immunoperoxidase staining protocol v1
Authors: Smith Yoland
Published: September 2022

This protocol details the procedure of light microscopy immunoperoxidase staining protocol.
Nano-CUT&Tag for multimodal profiling of the chromatin v2
Authors: Bartosovic Marek
Published: September 2022

Nano-CUT&Tag is a multimodal technology to profile several histone modifications at the same with single-cell resolution. Nano-CUT&Tag implements a novel Tn5 fusion proteins to anti-mouse and anti-rabbit secondary nanobodies. Optionally, ATAC-seq can be performed prior on the same sample to profile open chromatin at the same time. Novel tagmentation protocol, which involves two-step tagmentation by MeA and MeB oligonucleotides yields increased number of fragments per cell comparing to previous single-cell CUT&Tag protocols on 10x Genomics platform.