bluuebunny/crossref_metadata_2025 huggingface dataset:
Does Kinesiophobia Effect One Day Physical Activity Behaviour and Functionality of Young People with Ankylosing Spondylitis?
Authors: TOSUN AYDİN Gamze , DEMİRBUKEN İlksan , KAYA MUTLU Ebru , POLAT Mine Gulden
Published: February 2020

Objective: The aim of this study was to investigate the relationship between kinesiophobia, physical activity behaviour and functionality in patients with ankylosing spondylitis (AS).Methods: This study included 57 participants (mean age, 30.8 ± 5.19 years) in 2 groups of AS and healthy controls. One day physical activity behaviour was evaluated with tri-axial accelerometer. Tri-axial accelerometer was recorded physical activity domains and intensities for 24 hours. Participants completed clinical questionnaires assessing pain, kinesophobia, disease activity, and functionality. Kinesiophobia and pain were quantified by the Tampa Scale for Kinesiophobia and Short-Form McGill Pain Questionnaire. Function and disease activity were rated by using the Bath Ankylosing Spondylitis Functional Index, and Bath Ankylosing Spondylitis Disease Activity Score.Results: There was no correlation between kinesiophobia and one day physical activity behaviour in AS patients group. There was a negative correlation between high physical activity level and disease activity(p<0.05, r:-.519) and there was a negative correlation between high and moderate physical activity levels, and functionality (p <0.05, r:-.555 r:-395, respectively).Conclusion: According to the results of this study showed that; there was a relationship between disease activity, functionality, and one day physical activity behaviour. On the other hand, there was not any relation between pain intensity, kinesophobia and data obtained from accelerometer. Further studies with larger sample size and longer time periods should be carried out to reveal physical activity behaviours and its related factors in AS patients who will survive with this disease for years.
Evaluation of Drug-Related Problems in a Pediatric Bone Marrow Transplantation Unit Identified by a Clinical Pharmacist in-training in a 7-Month Period
Authors: ÖZDEMİR Nesligül , CELİKER Ayce , KUSKONMAZ Bulent Barıs , OKUR Fatma Visal , UCKAN CETİNKAYA Duygu
Published: February 2020

Objective:  This cross sectional study was performed to demonstrate the importance of clinical pharmacists’ participation in pediatric hematopoietic stem cell transplantation patient management with regards to the detection, prevention, and management of drug-related problems.Methods: The study was carried out from 1st October 2015 to 1st May 2016 in a pediatric bone marrow transplantation unit of a tertiary care hospital. The inpatients and outpatients between 0 to 18 years of age were included and the patients were monitored and evaluated for drug-related problems (interactions, side effects, preparation, and administration). A clinical pharmacist-in-training made recommendations to the physicians and the nurses on the problems that were identified.Results: Twenty inpatients and twenty-two outpatients were monitored during the study. In total, 245 problems were identified in the inpatients, 37.14 % of which were drug-related; 33 % of the drug-related problems were the side effects of cyclosporine. Eleven recommendations on drug-related problems were made to the physicians and six of them were for the problems identified in the inpatient services with regards to drug dosing and administration. Five recommendations regarding total parenteral nutrition, drug incompatibility, drug administration from the feeding tube, and drug side effects were made to the nurses. Twenty-nine information on the dosing, side effects, incompatibilities, administration, and preparation of the drugs, were given by the pharmacist to the physicians and the nurses.Conclusion: Clinical pharmacists’ participation will improve the detection and the management of drug-related problems in pediatric hematopoietic stem cell transplantation units in Turkey.
New Numerical Treatment for a Family of Two-Dimensional Fractional Fredholm Integro-Differential Equations
Authors: Darweesh Amer , Alquran Marwan , Aghzawi Khawla
Published: February 2020

In this paper, we present a robust algorithm to solve numerically a family of two-dimensional fractional integro differential equations. The Haar wavelet method is upgraded to include in its construction the Laplace transform step. This modification has proven to reduce the accumulative errors that will be obtained in case of using the regular Haar wavelet technique. Different examples are discussed to serve two goals, the methodology and the accuracy of our new approach.
Modulation of the Westerly and Easterly Quasi-Biennial Oscillation Phases on the Connection between the Madden–Julian Oscillation and the Arctic Oscillation
Authors: Song Lei , Wu Renguang
Published: February 2020

Previous studies have revealed the relationship between the Madden–Julian oscillation (MJO) and the Arctic Oscillation (AO). The MJO phase 2/3 is followed by the positive AO phase, and the MJO phase 6/7 is followed by the negative AO phase. This study reveals that the MJO phase 6/7–AO connection is modulated by the Quasi-Biennial Oscillation (QBO) through both tropospheric and stratospheric pathways during boreal winter. The MJO 2/3 phase and AO relationship is favored in both QBO easterly (QBOE) and westerly (QBOW) years because of the MJO-triggered tropospheric Rossby wave train from the tropics toward the polar region. The AO following the MJO 6/7 phase shifts to negative in QBOW years, but the MJO–AO connection diminishes in QBOE years. In QBOW years, the Asian-Pacific jet is enhanced, leading to more evident poleward propagation of tropospheric Rossby wave train, which contributes to the tropospheric pathway of the AO–MJO 6/7 connection. Besides, the enhanced Asian-Pacific jet in QBOW years is favorable for vertical propagation of planetary waves into the stratosphere in MJO phase 6/7, leading to negative AO, which indicates the stratospheric pathway of the AO–MJO 6/7 connection.
Coexistence of Lightning Generated Whistlers, Hiss and Lower Hybrid Noise Observed by e-POP (SWARM-E)–RRI
Authors: Maxworth Ashanthi , Hussey Glenn , Gołkowski Mark
Published: February 2020

Whistler mode waves play a major role in regulating the lifetime of trapped electrons in the Earth’s radiation belts. Specifically, interaction with whistler mode hiss waves is one of the mechanisms that maintains the slot region between the inner and outer radiation belts. The generation mechanism of hiss is a topic still under debate with at least three prominent theories present in the literature. Lightning generated whistlers in their ducted or non-ducted modes are considered to be one of the possible sources of hiss. We present a study of new observations from the Radio Receiver Instrument (RRI) on the Enhanced Polar Outflow Probe (ePOP: also known as SWARM-E). RRI consists of two orthogonal dipole antennas, which enables polarization measurements, when the satellite boresight is parallel to the geomagnetic field. Here we present 105 ePOP - RRI events from 2014–2018, in which lightning whistlers(75) and hiss waves(39) were observed. In more than 50% of those whistler observations, hiss found to co-exist. Moreover, the whistler observations are correlated with observations of wave power at the lower-hybrid resonance. The observations and a whistler mode ray-tracing study suggest that multiple-hop lightning induced whistlers can be a source of hiss and plasma instabilities in the magnetosphere.
GPU Parallelization of a Hybrid Pseudospectral Geophysical Turbulence Framework Using CUDA
Authors: Rosenberg Duane , Mininni Pablo D. , Reddy Raghu , Pouquet Annick
Published: February 2020

An existing hybrid MPI-OpenMP scheme is augmented with a CUDA-based fine grain parallelization approach for multidimensional distributed Fourier transforms, in a well-characterized pseudospectral fluid turbulence code. Basics of the hybrid scheme are reviewed, and heuristics provided to show a potential benefit of the CUDA implementation. The method draws heavily on the CUDA runtime library to handle memory management and on the cuFFT library for computing local FFTs. The manner in which the interfaces to these libraries are constructed, and ISO bindings utilized to facilitate platform portability, are discussed. CUDA streams are implemented to overlap data transfer with cuFFT computation. Testing with a baseline solver demonstrated significant aggregate speed-up over the hybrid MPI-OpenMP solver by offloading to GPUs on an NVLink-based test system. While the batch streamed approach provided little benefit with NVLink, we saw a performance gain of 30 % when tuned for the optimal number of streams on a PCIe-based system. It was found that strong GPU scaling is nearly ideal, in all cases. Profiling of the CUDA kernels shows that the transform computation achieves 15% of the attainable peak FlOp-rate based on a roofline model for the system. In addition to speed-up measurements for the fiducial solver, we also considered several other solvers with different numbers of transform operations and found that aggregate speed-ups are nearly constant for all solvers.
The Implication of Different Sets of Climate Variables on Regional Maize Yield Simulations
Authors: Srivastava Amit Kumar , Ceglar Andrej , Zeng Wenzhi , Gaiser Thomas , Mboh Cho Miltin , Ewert Frank
Published: February 2020

High-resolution and consistent grid-based climate data are important for model-based agricultural planning and farm risk assessment. However, the application of models at the regional scale is constrained by the lack of required high-quality weather data, which may be retrieved from different sources. This can potentially introduce large uncertainties into the crop simulation results. Therefore, in this study, we examined the impacts of grid-based time series of weather variables assembled from the same data source (Approach 1, consistent dataset) and from different sources (Approach 2, combined dataset) on regional scale crop yield simulations in Ghana, Ethiopia and Nigeria. There was less variability in the simulated yield under Approach 1, ranging to 58.2%, 45.6% and 8.2% in Ethiopia, Nigeria and Ghana, respectively, compared to those simulated using datasets retrieved under Approach 2. The two sources of climate data evaluated here were capable of producing both good and poor estimates of average maize yields ranging from lowest RMSE = 0.31 Mg/ha in Nigeria to highest RMSE = 0.78 Mg/ha under Approach 1 in Ghana, whereas, under Approach 2, the RMSE ranged from the lowest value of 0.51 Mg/ha in Nigeria to the highest of 0.72 Mg/ha in Ethiopia under Approach 2. The obtained results suggest that Approach 1 introduces less uncertainty to the yield estimates in large-scale regional simulations, and physical consistency between meteorological input variables is a relevant factor to consider for crop yield simulations under rain-fed conditions.
Retrospective and Randomized Analysis of Influence and Correlation of Clinical and Molecular Prognostic Factors in a Mono-Operative Series of 122 Patients with Glioblastoma Treated with STR or GTR
Authors: Salvati Maurizio , Bruzzaniti Placido , Relucenti Michela , Nizzola Mariagrazia , Familiari Pietro , Giugliano Marco , Scafa Anthony Kevin , Galletta Santi , Li Xiaobo , Chen Rui , Barbaranelli Claudio , Frati Alessandro , Santoro Antonio
Published: February 2020

Glioblastoma is a solid, infiltrating, and the most frequent highly malignant primary brain tumor. Our aim was to find the correlation between sex, age, preoperative Karnofsky performance status (KPS), presenting with seizures, and extent of resection (EOR) with overall survival (OS), progression-free survival (PFS), and postoperative KPS, along with the prognostic value of IDH1, MGMT, ATRX, EGFR, and TP53 genes mutations and of Ki67 through the analysis of a single-operator series in order to avoid the biases of a multi-operator series, such as the lack of homogeneity in surgical and adjuvant nonsurgical treatments. A randomized retrospective analysis of 122 patients treated by a single first operator at Sapienza University of Rome was carried out. After surgery, patients followed standard Stupp protocol treatment. Exclusion criteria were: (1) patients with primary brainstem and spinal cord gliomas and (2) patients who underwent partial resections (resection < 90%) or a biopsy exclusively for diagnostic purposes. Statistical analysis with a simultaneous regression model was carried out through the use of SPSS 25® (IBM). Results showed statistically significant survival increase in four groups: (1) patients treated with gross total resection (GTR) (p < 0.030); (2) patients with mutation of IDH1 (p < 0.0161); (3) patients with methylated MGMT promoter (p < 0.005); (4) patients without EGFR amplification or EGFRvIII mutation (p < 0.035). Higher but not statistically significant survival rates were also observed in: patients <75 years, patients presenting with seizures at diagnosis, patients affected by lesions in noneloquent areas, as well as in patients with ATRX gene mutation and Ki-67 < 10%.
T-Type Calcium Channels: A Potential Novel Target in Melanoma
Authors: Barceló Carla , Sisó Pol , Maiques Oscar , de la Rosa Inés , Martí Rosa M. , Macià Anna
Published: February 2020

T-type calcium channels (TTCCs) are overexpressed in several cancers. In this review, we summarize the recent advances and new insights into TTCC biology, tumor progression, and prognosis biomarker and therapeutic potential in the melanoma field. We describe a novel correlation between the Cav3.1 isoform and the increased basal autophagy in BRAFV600E-mutant melanomas and after acquired resistance to BRAF inhibitors. Indeed, TTCC blockers reduce melanoma cell viability and migration/invasion in vitro and tumor growth in mice xenografts in both BRAF-inhibitor-sensitive and -resistant scenarios. These studies open a new, promising therapeutic approach for disseminated melanoma and improved treatment in BRAFi relapsed melanomas, but further validation and clinical trials are needed for it to become a real therapeutic option.
PSA and PSA Kinetics Thresholds for the Presence of 68Ga-PSMA-11 PET/CT-Detectable Lesions in Patients with Biochemical Recurrent Prostate Cancer
Authors: Hoffmann Manuela Andrea , Buchholz Hans-Georg , Wieler Helmut J. , Miederer Matthias , Rosar Florian , Fischer Nicolas , Müller-Hübenthal Jonas , Trampert Ludwin , Pektor Stefanie , Schreckenberger Mathias
Published: February 2020

68Ga-PSMA-11 positron-emission tomography/computed tomography (PET/CT) is commonly used for restaging recurrent prostate cancer (PC) in European clinical practice. The goal of this study is to determine the optimum time for performing these PET/CT scans in a large cohort of patients by identifying the prostate-specific-antigen (PSA) and PSA kinetics thresholds for detecting and localizing recurrent PC. This retrospective analysis includes 581 patients with biochemical recurrence (BC) by definition. The performance of 68Ga-PSMA-11 PET/CT in relation to the PSA value at the scan time as well as PSA kinetics was assessed by the receiver-operating-characteristic-curve (ROC) generated by plotting sensitivity versus 1-specificity. Malignant prostatic lesions were identified in 77%. For patients that were treated with radical prostatectomy (RP) a PSA value of 1.24 ng/mL was found to be the optimal cutoff level for predicting positive and negative scans, while for patients previously treated with radiotherapy (RT) it was 5.75 ng/mL. In RP-patients with PSA value <1.24 ng/mL, 52% scans were positive, whereas patients with PSA ≥1.24 ng/mL had positive scan results in 87%. RT-patients with PSA <5.75 ng/mL had positive scans in 86% and for those with PSA ≥5.75 ng/mL 94% had positive scans. This study identifies the PSA and PSA kinetics threshold levels for the presence of 68Ga-PSMA-11 PET/CT-detectable PC-lesions in BC patients.
Neuroscience Application for the Analysis of Cultural Ecosystem Services Related to Stress Relief in Forest
Authors: Sacchelli Sandro , Grilli Gianluca , Capecchi Irene , Bambi Lorenzo , Barbierato Elena , Borghini Tommaso
Published: February 2020

The paper presents an integrated methodology to assess psychological and physiological responses of people when exposed to forests, with the main objective of assessing the suitability of different stands for stress recovery on the basis of tree species and density. From the methodological viewpoint, the study applies both a Restoration Outcome Scale (ROS) questionnaire and a neuroscientific technique grounded on electro-encephalographic (EEG) measurement. Results show different outcomes for conifers and broadleaves as well as a statistical significance of density in the evaluation of an individual’s emotional state. A forest with a high density of conifers and low density of broadleaves seems to be the proper combination for stress recovery. The differences among psychological stated preferences and EEG trends highlights potential conflict among “needs” and “wants” of people in the topic of stress relief. Potential applications of the research for health care and territorial marketing operations are suggested.
Functional Composition Changes of a Subtropical Monsoon Evergreen Broad-Leaved Forest Under Environmental Change
Authors: Zou Shun , Zhang Qianmei , Zhou Guoyi , Liu Shizhong , Chu Guowei , Li Ronghua , Ye Qing , Zhang Deqiang , Tang Xuli , Liu Juxiu , Huang Chumin , Li Yuelin , Meng Ze
Published: February 2020

Long-term studies have revealed that forest species composition was shifting under environment change and disturbance induced by loss of large trees. Yet, few studies explicitly analyzed their impacts on composition concurrently. To learn more about impacts of environment change and disturbance on driving forest community, we investigated shifts in functional composition over past 24 years in an old-growth subtropical forest in southern China. We analyzed nine traits that are mainly related to leaf nutrients, photosynthetic capacity, hydraulic conductivity, and drought tolerance of plants and examined hypotheses: (1) The functional composition change over time was directional instead of random fluctuation, (2) drought-tolerant species increased their abundance under soil dryness, (3) both environmental change and disturbance related to changes of functional composition significantly, and (4) initial trait values of quadrats strongly influenced their subsequent change rates in quadrat level (10 × 10 m). We found that species composition had shifted to favor species with high leaf nutrient content, high photosynthesis rate, high hydraulic conductivity, low water-use efficiency, and high drought tolerance traits, which was due to soil dryness and disturbance. These two factors explained 47–58% of quadrats’ trait value changes together. Considering rapidly increasing stem density, this pattern may indicate ecological processes of which disturbance provided numerous recruits of resource-acquisition strategy species and soil dryness conducted a selecting effect on shaping composition in the forest. Additionally, quadrats with initial trait values at the far end of change direction shifted faster in three traits, which also indicated that functional composition changes in quadrats were directional and homogenized. Our results implied that environment change and accompanied disturbance events possibly drove species composition change along a different trajectory in the subtropical forest that experienced high climatic variability.
EAOA: Energy-Aware Grid-Based 3D-Obstacle Avoidance in Coverage Path Planning for UAVs
Authors: Ghaddar Alia , Merei Ahmad
Published: February 2020

The presence of obstacles like a tree, buildings, or birds along the path of a drone has the ability to endanger and harm the UAV’s flight mission. Avoiding obstacles is one of the critical challenging keys to successfully achieve a UAV’s mission. The path planning needs to be adapted to make intelligent and accurate avoidance online and in time. In this paper, we propose an energy-aware grid based solution for obstacle avoidance (EAOA). Our work is based on two phases: in the first one, a trajectory path is generated offline using the area top-view. The second phase depends on the path obtained in the first phase. A camera captures a frontal view of the scene that contains the obstacle, then the algorithm determines the new position where the drone has to move to, in order to bypass the obstacle. In this paper, the obstacles are static. The results show a gain in energy and completion time using 3D scene information compared to 2D scene information.
Asymmetric Isolation and the Evolution of Behaviors Influencing Dispersal: Rheotaxis of Guppies above Waterfalls
Authors: Blondel Léa , Klemet-N’Guessan Sandra , Scott Marilyn E. , Hendry Andrew P.
Published: February 2020

Populations that are asymmetrically isolated, such as above waterfalls, can sometimes export emigrants in a direction from which they do not receive immigrants, and thus provide an excellent opportunity to study the evolution of dispersal traits. We investigated the rheotaxis of guppies above barrier waterfalls in the Aripo and Turure rivers in Trinidad—the later having been introduced in 1957 from a below-waterfall population in another drainage. We predicted that, as a result of strong selection against downstream emigration, both of these above-waterfall populations should show strong positive rheotaxis. Matching these expectations, both populations expressed high levels of positive rheotaxis, possibly reflecting contemporary (rapid) evolution in the introduced Turure population. However, the two populations used different behaviors to achieve the same performance of strong positive rheotaxis, as has been predicted in the case of multiple potential evolutionary solutions to the same functional challenge (i.e., “many-to-one mapping”). By contrast, we did not find any difference in rheotactic behavior above versus below waterfalls on a small scale within either river, suggesting constraints on adaptive divergence on such scales.
Designing Cyclic Job Rotations to Reduce the Exposure to Ergonomics Risk Factors
Authors: Diego-Mas Jose Antonio
Published: February 2020

Job rotation is an administrative solution to prevent work-related musculoskeletal disorders that has become widespread. However, job rotation schedules development is a complex problem. This is due to the multi-factorial character of the disorders and to the productive and organizational constraints of the real working environments. To avoid these problems, this work presents an evolutionary algorithm to generate rotation schedules in which a set of workers rotate cyclically over a small number of jobs while reducing the potential for injury. The algorithm is able to generate rotation schedules that optimize multiple ergonomics criteria by clustering the tasks into rotation groups, selecting the workers for each group, and determining the sequence of rotation of the workers to minimize the effects of fatigue. The algorithm reduces prolonged exposure to risks related to musculoskeletal injuries and simplifies the assignment of workers to different tasks in each rotation. The presented procedure can be an effective tool for the design of job-rotation schedules that prevent work-related musculoskeletal disorders while simplifying scheduled changeovers at each rotation and facilitating job monitoring.
Vitamin D and Indices of Bone and Carbohydrate Metabolism in Postmenopausal Women Subjected to a 12-Week Aerobic Training Program—The Pilot Study
Authors: Nowak Alicja , Dalz Monika , Śliwicka Ewa , Elegańczyk-Kot Helena , Kryściak Jakub , Domaszewska Katarzyna , Laurentowska Maria , Kocur Piotr , Pospieszna Barbara
Published: February 2020

The purpose of this study was to assess the effect of Nordic walking training on the indices of bone and carbohydrate metabolism in relation to 25(OH)D levels in postmenopausal women that were subjected to the outdoor systematic physical activity. The study was performed in 10 postmenopausal women, who participated in a 12-week Nordic walking exercise program, taking place during spring months (March to June). Anthropometric and biochemical parameters were measured before and after the training program. Serum concentrations of 25-hydroksycholekalciferol (25(OH)D), parathyroid hormone (PTH), insulin, glucose, osteocalcin (OC), C-terminal telopeptide of type I collagen (CTX), and calcium were determined. After the Nordic walking exercise program, a significant increase in the serum levels of 25(OH)D and CTX and a decrease in body mass, body mass index (BMI), fat mass, and PTH concentrations were observed. The findings of the present study suggest that 25(OH)D, as important metabolic regulator, plays a role in the modification of bone markers’ responses after the outdoor training program, independent of the physical activity effects.
Adsorption Characteristics and Mechanism of Bisphenol A by Magnetic Biochar
Authors: Wang Jinpeng , Zhang Ming
Published: February 2020

In this paper, biochar (BC) was prepared from discarded grapefruit peel and modified to prepare magnetic biochar (MBC). Physical and chemical properties of BC and MBC were characterized, and the results showed that the type of iron oxide loaded by MBC was γ-Fe2O3. Compared with BC, MBC has a larger specific surface area and pore volume, with more oxygen-containing functional groups on the surface. BC and MBC were used to adsorb and remove endocrine-disrupting chemical (EDC) bisphenol A (BPA) from simulated wastewater. The results showed that the adsorption kinetics and adsorption isotherm of BPA adsorption by BC and MBC were mainly in accordance with the pseudo-second-order kinetics model and the Langmuir model. This indicates that the adsorption of BPA on BC and MBC is mainly a chemically controlled monolayer adsorption. Adsorption thermodynamics show that BC and MBC adsorption of BPA is a spontaneous exothermic reaction, and lowering the temperature is conducive to the adsorption reaction. The effect of solution pH on the adsorption of BPA by both was significant. The optimum pH for BC and MBC to absorb BPA was 6 and 3, respectively. The concentration of Na+ in the range of 0–0.10 mol·L−1 can promote the adsorption of BPA to MBC. MBC loaded with γ-Fe2O3 not only has excellent magnetic separation ability, but can also reach about 80% of the initial adsorption capacity after four cycles of adsorption. By analyzing the adsorption mechanism, it was found that the H-bond and the π–π electron donor–acceptor interaction (EDA) were the main forces for BC and MBC to adsorb BPA.
Influence of Freeze–Thaw Cycles and Binder Dosage on the Engineering Properties of Compound Solidified/Stabilized Lead-Contaminated Soils
Authors: Yang Zhongping , Wang Yao , Li Denghua , Li Xuyong , Liu Xinrong
Published: February 2020

The solidification/stabilization (S/S) method is the usual technique for the remediation of soils polluted by heavy metal in recent years. However, freeze–thaw cycles, an important physical process producing weathering of materials, will affect the long-term stability of engineering characteristics in solidified contaminated soil. In addition, it is still questionable whether using large dosages of binders can enhance the engineering properties of solidified/stabilized contaminated soils. In this study, the three most commonly used binders (i.e., cement, quicklime, and fly ash), alone and mixed in different ratios, were thus added to lead-contaminated soil in various dosages, making a series of cured lead-contaminated soils with different dosages of binders. Afterward, unconfined compression strength tests, direct shear tests, and permeability tests were employed on the resulting samples to find the unconfined compressive strength (UCS), secant modulus ( E 50 ), internal friction angle ( φ ), cohesion ( c ), and permeability coefficient ( k ) of each solidified/stabilized lead-contaminated soil after 0, 3, 7, and 14 days of freeze–thaw cycles. This procedure was aimed at evaluating the influence of freeze–thaw cycle and binder dosage on engineering properties of solidified/stabilized lead-contaminated soils. Results of our experiments showed that cement/quicklime/fly ash could remediate lead-contaminated soils. However, it did not mean that the more the dosage of binder, the better the curing effect. There was a critical dosage. Excessive cementation of contaminated soils caused by too much binder would result in loss of strength and an increase in permeability. Furthermore, it was found that UCS,   E 50 , φ , c , and k values generally decreased with the increase in freeze–thaw cycle time—a deterioration effect on the engineering characteristics of solidified lead-contaminated soils. Avoiding excessive cementation, 2.5% cement or quicklime was favorable for the value of E 50 while a 2.5% fly ash additive was beneficial for the k value. It is also suggested that if the freeze–thaw cycle continues beyond the period supported by excessive cementation, such a cycle will rapidly destroy the original structure of the soil and create large cracks, leading to an increase in permeability. The results also showed that the contaminated soils with a larger dosage of binders exhibited more significant deterioration during freeze–thaw cycles.
Socioeconomic Inequalities in Child Malnutrition in Bangladesh: Do They Differ by Region?
Authors: Hasan Mohammad Monirul , Uddin Jalal , Pulok Mohammad Habibullah , Zaman Nabila , Hajizadeh Mohammad
Published: February 2020

Socioeconomic inequality in child malnutrition is well-evident in Bangladesh. However, little is known about whether this inequality differs by regional contexts. We used pooled data from the 2011 and 2014 Bangladesh Demographic and Health Survey to examine regional differences in socioeconomic inequalities in stunting and underweight among children under five. The analysis included 14,602 children aged 0–59 months. We used logistic regression models and the Concentration index to assess and quantify wealth- and education-related inequalities in child malnutrition. We found stunting and underweight to be more concentrated among children from poorer households and born to less-educated mothers. Although the poverty level was low in the eastern regions, socioeconomic inequalities were greater in these regions compared to the western regions. The extent of socioeconomic inequality was the highest in Sylhet and Chittagong for stunting and underweight, respectively, while it was the lowest in Khulna. Regression results demonstrated the protective effects of socioeconomic status (SES) on child malnutrition. The regional differences in the effects of SES tend to diverge at the lower levels of SES, while they converge or attenuate at the highest levels. Our findings have policy implications for developing programs and interventions targeted to reduce socioeconomic inequalities in child malnutrition in subnational regions of Bangladesh.
Assessment of Ambient Air Toxics and Wood Smoke Pollution among Communities in Sacramento County
Authors: Brown Steven G. , Lam Snyder Janice , McCarthy Michael C. , Pavlovic Nathan R. , D’Andrea Stephen , Hanson Joseph , Sullivan Amy P. , Hafner Hilary R.
Published: February 2020

Ambient air monitoring and phone survey data were collected in three environmental justice (EJ) and three non-EJ communities in Sacramento County during winter 2016–2017 to understand the differences in air toxics and in wood smoke pollution among communities. Concentrations of six hazardous air pollutants (HAPs) and black carbon (BC) from fossil fuel (BCff) were significantly higher at EJ communities versus non-EJ communities. BC from wood burning (BCwb) was significantly higher at non-EJ communities. Correlation analysis indicated that the six HAPs were predominantly from fossil fuel combustion sources, not from wood burning. The HAPs were moderately variable across sites (coefficient of divergence (COD) range of 0.07 for carbon tetrachloride to 0.28 for m- and p-xylenes), while BCff and BCwb were highly variable (COD values of 0.46 and 0.50). The BCwb was well correlated with levoglucosan (R2 of 0.68 to 0.95), indicating that BCwb was a robust indicator for wood burning. At the two permanent monitoring sites, wood burning comprised 29–39% of the fine particulate matter (PM2.5) on nights when PM2.5 concentrations were forecasted to be high. Phone survey data were consistent with study measurements; the only significant difference in the survey results among communities were that non-EJ residents burn with indoor devices more often than EJ residents.
Frenetic, under-Challenged, and Worn-out Burnout Subtypes among Brazilian Primary Care Personnel: Validation of the Brazilian “Burnout Clinical Subtype Questionnaire” (BCSQ-36/BCSQ-12)
Authors: Demarzo Marcelo , García-Campayo Javier , Martínez-Rubio David , Pérez-Aranda Adrián , Miraglia Joao Luiz , Hirayama Marcio Sussumu , de Salvo Vera Morais Antonio , Cicuto Karen , Favarato Maria Lucia , Terra Vinicius , de Oliveira Marcelo Batista , García-Toro Mauro , Modrego-Alarcón Marta , Montero-Marín Jesús
Published: February 2020

Primary healthcare personnel show high levels of burnout. A new model of burnout has been developed to distinguish three subtypes: frenetic, under-challenged, and worn-out, which are characterized as overwhelmed, under-stimulated, and disengaged at work, respectively. The aim of this study was to assess the psychometric properties of the long/short Brazilian versions of the “Burnout Clinical Subtypes Questionnaire” (BCSQ-36/BCSQ-12) among Brazilian primary healthcare staff and its possible associations with other psychological health-related outcomes. An online cross-sectional study conducted among 407 Brazilian primary healthcare personnel was developed. Participants answered a Brazil-specific survey including the BCSQ-36/BCSQ-12, “Maslach Burnout Inventory-General Survey”, “Utrecht Work Engagement Scale”, “Hospital Anxiety/Depression Scale”, “Positive-Negative Affect Schedule”, and a Visual Analogue Scale of guilt at work. The bifactor was the model with the best fit to the data using the BCSQ-36, which allowed a general factor for each subtype. The three-correlated factors model fit better to the BCSQ-12. Internal consistence was appropriate, and the convergence between the long-short versions was high. The pattern of relationships between the burnout subtypes and the psychological outcomes suggested a progressive deterioration from the frenetic to the under-challenged and worn-out. In sum, the Brazilian BCSQ-36/BCSQ-12 showed appropriate psychometrics to be used in primary healthcare personnel.
Environmental and Health Effects of Ventilation in Subway Stations: A Literature Review
Authors: Wen Yueming , Leng Jiawei , Shen Xiaobing , Han Gang , Sun Lijun , Yu Fei
Published: February 2020

Environmental health in subway stations, a typical type of urban underground space, is becoming increasingly important. Ventilation is the principal measure for optimizing the complex physical environment in a subway station. This paper narratively reviews the environmental and health effects of subway ventilation and discusses the relevant engineering, environmental, and medical aspects in combination. Ventilation exerts a notable dual effect on environmental health in a subway station. On the one hand, ventilation controls temperature, humidity, and indoor air quality to ensure human comfort and health. On the other hand, ventilation also carries the potential risks of spreading air pollutants or fire smoke through the complex wind environment as well as produces continuous noise. Assessment and management of health risks associated with subway ventilation is essential to attain a healthy subway environment. This, however, requires exposure, threshold data, and thereby necessitates more research into long-term effects, and toxicity as well as epidemiological studies. Additionally, more research is needed to further examine the design and maintenance of ventilation systems. An understanding of the pathogenic mechanisms and aerodynamic characteristics of various pollutants can help formulate ventilation strategies to reduce pollutant concentrations. Moreover, current comprehensive underground space development affords a possibility for creating flexible spaces that optimize ventilation efficiency, acoustic comfort, and space perception.
A Self-Reflection Program for Smoking Cessation in Adolescents: A Phenomenological Study
Authors: Sim Inok , Hwang Eunjeong , Sin Bora
Published: February 2020

The study aimed to understand the experiences of adolescent smokers who participated in a self-reflection program for smoking cessation and to develop the theoretical basis for constructing similar programs. The program is unique from other smoking cessation programs in that it seeks to be creative and allow participants to establish an individualized vision for themselves. The participants, ten students from middle and high schools located in cities A and S, were interviewed right after the program ended. Data were collected from August to December 2019 and analyzed using a phenomenological approach to understand participant experiences in depth. The analysis revealed five major themes: ‘Uniqueness of the Program,’ ‘Perception of Smoking Cessation,’ ‘Positive Reflection on Life,’ ‘Understanding Others,’ and ‘A Search for Hope and Vision in Life.’ The findings revealed that their smoking behaviors were changed through self-reflection and enhancement of self-efficacy and that the program facilitated the formation of identity and vision for the future, which may indirectly strengthen the motivation for adolescent smokers to quit smoking. These findings suggest the need for a smoking cessation program that enhances self-concept and self-esteem. Moreover, it highlights the importance of follow-up research to ensure effectiveness and the need to develop programs with creative content.
Genetic Diversity and Phylogenetic Analysis of Human Bocavirus 2 in Pediatric Patients with Acute Gastroenteritis in Taiwan
Authors: Lin Marco Yung-Cheng , Chan Hsiu-Chuan , Chi Hsin , Chiu Shu-Chun , Nora-Krukle Zaiga , Rasa-Dzelzkaleja Santa , Vilmane Anda , Murovska Modra , Lin Jih-Hui , Liu Hsin-Fu
Published: February 2020

Human bocavirus (HBoV) is a causative agent of respiratory and gastrointestinal diseases worldwide. Four HBoV species (HBoV1-4) have been identified so far. Although a previous report has documented the HBoV association with acute gastroenteritis (AGE) in Taiwan, their epidemiology, genetic diversity, and phylogenetic relationships remain unclear. In this study, we focused on an investigation of these unsolved issues, which will help to reveal molecular epidemiology and phylogeny of the circulating HBoV2 in Taiwan. A total of 176 stool samples were collected from children with AGE for this study. PCR amplification and sequencing on the VP1 gene region were used to identify species. Phylogenetic analysis was conducted by maximum-likelihood and neighbor-joining methods. Selection pressure was also estimated to obtain HBoV evolutionary information. Our results showed the prevalence of HBoV in AGE children was 8.5%, of which HBoV1 was the predominant species (6.3%), followed by HBoV2 (2.3%). Phylogenetic analysis showed those Taiwanese HBoV2 strains have significant genetic variability and can be divided into two clusters. One belongs to HBoV2 genotype A and the other forms an independent unclassified cluster. The nucleotide distance between that independent cluster and the known HBoV2 genotypes was more than 5%, suggesting a new HBoV2 genotype. No positive selection site was found and the virus was under purifying selection. This is the first report to reveal HBoV2 genetic diversity and phylogenetic relationships among AGE children in Taiwan. We find that HBoV2 may have been introduced into the country by multiple origins, and a potential new HBoV2 genotype is proposed.
Personality Factors and Sick Leave Days. Evidence from a Nationally Representative Longitudinal Study in Germany.
Authors: Raynik Yulia I. , König Hans-Helmut , Hajek André
Published: February 2020

Background: The question of whether employees’ sickness absence from the workplace depends on personality has been researched. Existing evidence mostly stems from cross-sectional studies, mainly showing that personality factors were not associated with the number of sick leave days, except for neuroticism, which was positively associated with sick leave days. Based on the above, it remains an under researched question whether intraindividual changes in personality factors are associated with changes in sick leave days. Thus, based on a nationally representative sample, the current study aimed to investigate the relationship between personality factors and sick leave days longitudinally based on a nationally representative sample of individuals in Germany. Methods: The present study used data from the German Socio-Economic Panel (GSOEP), a longitudinal survey of private households in Germany. Information from the years 2005, 2009, 2013 were used. The Big Five Inventory-GSOEP (BFI-S) was used to measure personality. Sick leave days in the preceding year were recorded. Poisson fixed effects regressions were used. Results: Adjusting for potential confounders, regressions showed that increases in neuroticism were associated with increased sick leave days. The longitudinal association between extraversion and sick leave days was marginally significant (p < 0.10). Other personality factors were not significantly associated with sick leave days. In addition, sick leave days increased with worsening self-rated health, presence of severe disability and increasing age. Conclusions: The findings of the current study highlight the association between neuroticism and sick leave days longitudinally. Further research is required to elucidate the underlying mechanisms.
Evaluation of Respiratory Muscular Strength Compared to Predicted Values in Patients with Stroke
Authors: Ramos Sarah Maria , Silva Daniela Maciel da , Buchaim Daniela Vieira , Buchaim Rogério Leone , Audi Mauro
Published: February 2020

The purpose of this study was to evaluate the inspiratory and expiratory muscle strength of individuals affected by stroke and to compare it with the predicted values in the literature considering their corresponding age. Respiratory muscle strength was evaluated in 22 elderly people who had sequels of stroke, four with right hemiparesis, 16 with left hemiparesis and two with bilateral, of ages ranging from 34 to 82 years. The collected data were submitted to statistical analysis using a Mann–Whitney test to evaluate if there was a significant difference in the average data collected when compared with a mean of the predicted data in the literature. Fourteen men and eight women were evaluated, who obtained mean values of 71.85 cmH2O and 57.75 cmH2O, respectively, for a maximal inspiratory pressure (MIP), and when compared to the predicted values for men and women, 105.41 cmH2O (p-value 0.0019) and 80.57 cmH2O (p-value 0.00464) were significantly lower. For a maximal expiratory pressure (MEP), the mean value obtained for men was 62.28 cmH2O and 49.5 cmH2O for women, whereas the predicted values in the literature were 114.79 cmH2O (p-value < 0.0001) and 78, 46 cmH2O (p-value 0.0059), respectively. In the statistical analysis, it was possible to notice that the studied population did not reach the predicted age indexes and that there was a significant difference between the median columns. In conclusion, there is a weakness in the respiratory muscles of hemiparetic men and women due to stroke.
Co-Creating a Virtual Alcohol Prevention Simulation with Young People
Authors: Vallentin-Holbech Lotte , Dalgaard Guldager Julie , Dietrich Timo , Rundle-Thiele Sharyn , Majgaard Gunver , Lyk Patricia , Stock Christiane
Published: February 2020

Collaborative knowledge generation and involvement of users is known to improve health promotion intervention development, but research about the roles and perspectives of users in the co-creation process is sparse. This research aimed to study how young people perceived their involvement in a co-creation process focussed on the development of a gamified virtual reality (VR) simulation—VR FestLab. The Living Lab methodology was applied to structure and guide the co-creation process. Living Lab participants were comprised of students, health promotion practitioners, researchers, and film and gaming experts who collaboratively designed and created the content and structure of the VR FestLab. Semi-structured interviews were conducted with nine students who participated in the Living Lab and represented young end users. Interviews were tape-recorded, transcribed and thematically analysed. Students described that they had influence on their tasks. They felt included and expressed that the collaboration with and feedback from peers and other stakeholders increased their self-efficacy and empowered them to take ownership and generate new ideas. Participants voiced that they lacked information about the final production of VR FestLab. Co-creation guided by the Living Lab methodology produced added value in terms of empowerment and increased self-efficacy for the students involved. Future Living Labs should plan for communication with participants about further development and implementation processes following ideation and prototyping phase.
Physical and Psychological Factors Affecting Falls in Older Patients with Arthritis
Authors: Byun Mikyong , Kim Jiyeon , Kim Moonho
Published: February 2020

As the population ages, falls are becoming one of the leading causes of morbidity and mortality. Joint disease (either osteoarthritis or rheumatoid arthritis) is a well-known predictor of falls, and these medical conditions increase in accordance with the aging population. This study aimed to describe individual, physical, and psychological characteristics between older adults with and without a fall history. Further, we aimed to identify statistically significant physical or psychological factors associated with falls by controlling individual variables. We analyzed data from the 2014 Survey of Living Conditions and Welfare Needs of Korean Older Adults. Adults aged 65 years or over with doctor-diagnosed joint disease were eligible. A total of 2707 women and 784 men (n = 3491) were enrolled. Of these, 1174 patients suffered a fall within a year (average number of falls = 2.4). We adopted individual variable-adjusted models and found that limited activities of daily living (odds ratio (OR) 1.4, 95% confidence interval (CI) 1.04–1.87), fear of falling (OR 7.18, 95% CI 4.26–12.09), and depression (OR 1.28, 95% CI 1.09–1.50) significantly increased fall risks on logistic regression analysis. Our findings suggest that physical and psychological factors, especially the fear of falling, need to be addressed to prevent falls in elderly patients with arthritis.