bluuebunny/crossref_metadata_2025 huggingface dataset:
Remoção de raiz residual do seio maxilar: Técnica de Caldwell-Luc modificada
Authors: Ganzaroli Vinícius Franzão , Bacelar Ana Carolina Zucon , Pereira Estêvão Lopes , Costa Leandro Lemes da , Rocha Arthur Nascimento , Kirasuke Arthur Michellim , Ponzoni Daniela
Published: August 2024

As exodontias são procedimentos odontológicos realizados rotineiramente na prática clínica odontológica e em muitos casos encontramos um íntimo contato das raízes dos dentes superiores com o seio maxilar. Tal estrutura anatômica contribui para deixar o viscerocrânio mais leve, desempenhando um papel crucial no sistema respiratório, aquecendo o ar inspirado e contribuindo para a ressonância vocal. Por apresentar grande proximidade com os dentes superiores, diversas complicações patológicas e iatrogenias podem acontecer durante a realização de exodontias, necessitando de intervenções cirúrgicas para serem solucionadas. Dentre os procedimentos cirúrgicos, a técnica de Caldwell-Luc modificada, possibilita a remoção de corpos estranhos do seio maxilar, inspeção detalhada, facilidade de execução e grande eficácia. O objetivo do presente trabalho é relatar um caso clínico no qual foi realizada a remoção bem-sucedida de um remanescente de raiz residual do seio maxilar utilizando a técnica de Caldwell-Luc modificada, destacando a importância do procedimento na prática cirúrgica contemporânea. Conclui-se que a presença de corpos estranhos do seio maxilar deve ser imediatamente abordada, sendo o acesso cirúrgico Caldwell-Luc modificado uma ótima escolha para resolução destes casos, evitando o surgimento de quadros infecciosos locais e sistêmicas.
Impact of processed and ultra-processed foods on colorectal cancer risk: Mechanisms, dietary factors, and protective compound
Authors: Lombello Suellen Maroco Cruzeiro , Dutra Isadora Monteiro , Silveira Isadora Valério da , Gomides Antônio Frederico de Freitas , Velloso-Rodrigues Cibele
Published: August 2024

Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide, linked to behavioral factors such as a sedentary lifestyle and smoking, environmental factors like pollution, and nutritional factors including a diet rich in red and processed meats. Some foods are associated with potential carcinogenicity, while others act as protective factors. This review aims to report the contribution of processed and ultra-processed foods to the etiopathogenesis of CRC and explore the role of protective diets. The article is an integrative review conducted in PubMed and VHL databases using the descriptors “colorectal cancer” and “processed foods.” Studies published in the last five years addressing the relationship between these foods and CRC development were included. Potentially carcinogenic substances in processed foods, such as heterocyclic amines, nitrosamines, heme iron, industrial fatty acids, aromatic hydrocarbons, sialic acid sugar, and additives like titanium dioxide, were associated with colon and rectal neoplasms. Additional associations were found with the human microbiome, packaging materials, and food preparation methods. Conversely, several food components can protect against CRC. The consumption of processed and ultra-processed foods can significantly increase CRC risk through mechanisms like inflammation, oxidative stress, gene expression changes, and genetic material damage. The intestinal flora profile may be protective against CRC but is altered when processed and ultra-processed foods are included in the diet. Fiber, phytochemicals, and spices present in plant foods are consistently reported to have anticarcinogenic effects.
O cuidado intensivo neonatal na perspectiva da teoria ambientalista
Authors: Weller Tatiane Gabriela , Getelina Caroline Ottobeli , Alves Ana Luíza da Silva
Published: August 2024

Anualmente, segundo a Organização Mundial da Saúde (OMS, 2021) nascem cerca de 30 milhões de bebês prematuros em todo o mundo. Ao nascimento, o bebê é classificado quanto sua idade gestacional, sendo prematuro aquele que nasce com menos de 36 semanas e seis dias de gestação. Objetivo: O presente estudo tem por objetivo compreender como o cuidado é desenvolvido e percebido junto a UTIN na perspectiva da Teoria Ambientalista. Metodologia: Trata-se de uma pesquisa qualitativa, realizada no ano que 2022 na UTIN do Hospital de Clínicas de Passo Fundo, Rio Grande do Sul.  Os participantes da pesquisa foram profissionais da área da enfermagem, incluindo enfermeiros e técnicos de enfermagem que atuavam na UTIN, foram escolhidos 15 profissionais por meio de amostra aleatória simples. Resultados: Para fins de análise, foram criadas categorias que orientaram a análise de resultados, as quais ficaram assim constituídas: Da percepção do ambiente para uma melhor assistência ao neonato; Da percepção da equipe de enfermagem acerca do ambiente e sua interferência junto a assistência na UTIN. Conclusão: Na análise da opinião da equipe de enfermagem no que se refere ao ambiente interferir na recuperação do neonato, observa-se que os profissionais tem a percepção de como o ambiente pode auxiliar positiva ou negativamente no tratamento do bebê. Ao refletir acerca de outros fatores que se incluem na questão ambiental com o risco de infecções, observa-se que os profissionais tem a consciência que o risco é iminente e exige uma atenção contínua.
Índice de cárie em crianças de 6 a 12 anos, nas unidades educacionais “agua dulce e lago victoria” do município de Puerto Gonzalo Moreno-Bolívia
Authors: Santos Alcione Costa dos , Dominguez Gerson Pereira , Vera Juan Miguel Antezana , Vera Saul Alfredo Antezana
Published: August 2024

Um levantamento epidemiológico de saúde bucal em crianças possibilita planejar, implementar ações em saúde e monitorar comportamentos de doenças. visto que, a cárie é um tipo de desequilíbrio persistente que ocorre tanto em países desenvolvidos quanto em desenvolvimento. O objetivo deste estudo foi identificar o índice de cárie em crianças de 6 a 12 anos, usando os índices epidemiológicos ceo-d e CPO-D, em duas unidades educacionais de “Agua Dulce e Lago Victoria”, no município de Puerto Gonzalo Moreno, Bolívia. A metodologia utilizada corresponde a um estudo epidemiológico descritiva dois índices de caries em crianças, por meio da observação e da identificação da pesquisa, a amostragem foi composta por alunos com idades entre 6 e 12 anos, em duas unidades educacionais de “Agua Dulce e Lago Victoria”, localizadas no município de Puerto Gonzalo Moreno na Bolívia. Os resultados mostraram que, o índice ceo-d foi de 6,7 e CPO-D 2,3 nas duas unidades educacionais, como também que, as crianças do gênero masculino apresentaram o CPO-D foi de 2,1 e do gênero feminino com 2,7. Apesar de fornecerem dados sobre a prevalência de cárie, não abordam diretamente as causas subjacentes, como fatores socioeconômicos ou comportamentais. Em conclusão, existe um alto índice de cáries em meninos e meninas em ambas as comunidades, isso se deve à falta de conhecimento sobre higiene bucal nas famílias, além da falta de recursos financeiros para a compra de escovas e cremes dentais para os filhos.
Floral therapy and its use in dentistry: A bibliographic research
Authors: Santos Pedro Guimarães Sampaio Trajano dos , Brandão Rita de Cássia Vieira de Vasconcelos Cavalcanti , Cunha Rodolfo Scavuzzi Carneiro , Silveira Fabiana Moura da Motta , Marques Filho Eudoro de Queiroz , Valença Paula Andréa de Melo , Silva Luciano Barreto
Published: August 2024

Objective: Search for articles, books and other studies on flower therapy from its functioning, origin and benefits in dentistry. Methodology: Searches were made for online materials, aiming to obtain information, studies, articles and other research through the following databases: The Cochrane Library, Web of Science, Research, society and development journal, DeCs, Science Direct, VHL /BIREME, PUBMED Central, Scielo and Google Academy. Results: Our search resulted in 37 articles. Conclusion: Floral Therapy, in addition to being used in various health settings, has benefits in post and pre dental care, such as its function against fear and anxiety.
Hallazgo incidental de beta talasemia en paciente gestante de alto riesgo obstétrico
Authors: Lopez Muñoz Diego Fernando , Agudelo Valencia Daniela Andrea , Cruz Becerra Oscar Eduardo , Ramirez Muñoz Sergio , Sanchez Escobar Manuela , Trivino Montoya Thana Manuella , Cifuentes Muñoz Maria Alejandra
Published: August 2024

La talasemia es un conjunto de anomalías genéticas que resultan en la inadecuada síntesis de hemoglobina, cuya clínica varía desde la sintomatología hasta la muerte fetal. Se realizó un estudio sobre un hallazgo de betatalasemia en una mujer embarazada, con el objetivo de destacar los aspectos clínicos, diagnóstico, tratamiento y calidad de vida de la paciente. Se recolectaron datos de la historia clínica de la paciente y se utilizó el NCBI como fuente de referencia. La paciente presenta una anemia con valores bajos de hemoglobina, hematocrito, VCM, HCM y CHCM. Los niveles de hierro sérico total y porcentaje de saturación están notablemente disminuidos. Además, la electroforesis capilar de alta resolución muestra un patrón anormal con bandas sugestivas de beta talasemia. En ecografía de control de crecimiento fetal a las 32 semanas se detecta alteración en el perfil de crecimiento fetal, con estudio Doppler feto placentario alterado. Se diagnostica Restricción del crecimiento intrauterino estadio 1 y se decide finalizar la gestación a las 37 semanas. El resultado neonatal es un recién nacido con bajo peso al nacer. El manejo de estas pacientes requiere un enfoque multidisciplinario que incluya un monitoreo riguroso, una atención prenatal personalizada y una planificación cuidadosa del parto.
Hospital morbidity and mortality of elderly people due to Diabetes Mellitus in Brazil: An epidemiological analysis from 2014 to 2023
Authors: Segateli Leonardo , Oliveira Marcos Abelbeck de , Coca Matheus Luis Leite , Soares Querem Hapuque , Mancini Ana Paula Neto , Suez Suellen de Oliveira , Crepaldi Glaucia Dellaqua
Published: August 2024

Objetivo: analisar o perfil de morbimortalidade de idosos por DM no Brasil, no período entre 2014 e 2023. Métodos: estudo epidemiológico, retrospectivo, com abordagem quantitativa sobre a morbimortalidade hospitalar de idosos por DM, através da coleta de dados secundários extraídos do Departamento de Informática do Sistema único de Saúde. Foram analisados todos os registros hospitalares de idosos (a partir de 60 anos), relativos às internações e óbitos relacionados ao DM nas cinco regiões brasileiras. Resultados: foram registradas 705.722 internações hospitalares de idosos por DM no Brasil, sendo a maioria do sexo feminino (51,9%), destacando a região Nordeste com o maior número de internações. Com relação a mortalidade foram registrados 43.550 óbitos, demonstrando alta taxa de mortalidade (10,92) para idosos com 80 anos ou mais, atingindo principalmente pessoas autodeclaradas pretas (n=16.854). Os custos com internação hospitalar geraram um impacto financeiro superior a 515,4 milhões de reais ao SUS, a região sudeste ocupou o primeiro lugar de gastos. Conclusão: A análise epidemiológica da morbimortalidade hospitalar de idosos por Diabetes Mellitus na última década revelou tendências preocupantes e desafios significativos para o sistema de saúde. Esses dados refletem não apenas o envelhecimento da população, mas também a prevalência elevada de comorbidades que complicam o manejo do DM e contribuem para desfechos adversos.
Coffee market price as a reflection of the brazilian harvest
Authors: Ferraz Vítor Almeida , Silva Gustavo de Souza e
Published: August 2024

Brazilian agribusiness has great importance in the constitution of national gross domestic product, reaching values of more than 27% representativeness. Within the agricultural products we have coffee as one of the great crops in our country. As it is known its market value fluctuates, like all products, by the most diverse factors. This work aimed to evaluate the existence or not of a correlation in the market price of coffee with production factors in Brazil. Variation along the years of Brazilian total coffee production, total area in production and area of crop formation was explored via a Pearson’s correlation analysis with significance of 95%. Pearson's correlation analysis identified a negative correlation of -0.33 between the negotiation price of the coffee sack (60 kg) and the total production volume of the Brazilian crop. Considering that the market value of this product can be affected by numerous factors we conclude the significant existence of this correlation.
GIDA AZO BOYALARININ ERKEK REPRODÜKTİF TOKSİSİTESİ YÖNÜNDEN DEĞERLENDİRİLMESİ
Authors: Korkut Çelikateş Büşra , Baysal Merve
Published: August 2024

Amaç: Sentetik gıda boyaları, endüstriyel ve ticari ürünlerin görünümünü iyileştiren ve lezzetini artıran önemli bileşenlerden biridir. Ancak, çoğunlukla azo fonksiyonel gruplar ve aromatik halkalar içeren kimyasal yapılarından dolayı, bu maddelerin insan sağlığına potansiyel olarak zararlı olabileceği konusunda endişeler bulunmaktadır. Birçok çalışma, azo grubuna dahil olan boyaların aşırı duyarlılık reaksiyonlarına neden olabilen nitro türevleri olduğunu, bağırsak mikroflorası tarafından oluşan metabolitlerin mutajenez ve karsinojenez çalışmalarının odak noktasında yer aldığını belirtmiştir. Çeşitli çalışmalar, azo boyaların erkek reprodüktif sistemi üzerinde, özellikle de sperm parametrelerinde olumsuz etkileri olduğunu göstermiştir. Bu etkilere serum testosteron konsantrasyonundaki azalma da eşlik etmiştir.
Sonuç ve Tartışma: Gıda azo boyalarıyla ilgili çalışmalara olan ilginin artarak devam etmesi olası toksisite mekanizmalarını aydınlatma ihtiyacını beraberinde getirmiştir. Bu derlemede yaygın kullanılan gıda azo boyalarıyla ilgili genel bilgiler sunulmuş ve erkek reprodüktif sistem üzerindeki olumsuz etkilerine dair yapılan in vivo çalışmalar sonuçlarıyla değerlendirilmiştir.
Immersive simulation in nursing and midwifery education: a systematic review
Authors: Yahya Lahoucine Ben , Naciri Aziz , Radid Mohamed , Chemsi Ghizlane
Published: August 2024

Purpose: Immersive simulation is an innovative training approach in health education that enhances student learning. This study examined its impact on engagement, motivation, and academic performance in nursing and midwifery students.Methods: A comprehensive systematic search was meticulously conducted in 4 reputable databases—Scopus, PubMed, Web of Science, and Science Direct—following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The research protocol was pre-registered in the PROSPERO registry, ensuring transparency and rigor. The quality of the included studies was assessed using the Medical Education Research Study Quality Instrument.Results: Out of 90 identified studies, 11 were included in the present review, involving 1,090 participants. Four out of 5 studies observed high post-test engagement scores in the intervention groups. Additionally, 5 out of 6 studies that evaluated motivation found higher post-test motivational scores in the intervention groups than in control groups using traditional approaches. Furthermore, among the 8 out of 11 studies that evaluated academic performance during immersive simulation training, 5 reported significant differences (P<0.001) in favor of the students in the intervention groups.Conclusion: Immersive simulation, as demonstrated by this study, has a significant potential to enhance student engagement, motivation, and academic performance, surpassing traditional teaching methods. This potential underscores the urgent need for future research in various contexts to better integrate this innovative educational approach into nursing and midwifery education curricula, inspiring hope for improved teaching methods.
Macrocyclic peptide inhibitors of viral fusion proteins
Authors:   , Thijssen Vito
Published: August 2024

Pandemic outbreaks of viruses present a significant global challenge, necessitating continuous updates to vaccines and exploration of new antiviral drugs. This thesis explores a strategy targeting the coat glycoproteins of two pandemic viruses to discover new broadly active antiviral drugs. The focus is on viral fusion proteins and cyclic peptide selection systems, emphasizing the need for innovative approaches due to emerging drug resistance. The RaPID system, which uses mRNA display and in vitro translation is used to screen for antiviral cyclic peptides. In chapter 2, the RaPID system is used to identify macrocyclic peptide inhibitors against Influenza A hemagglutinin (HA) protein. Peptides targeting the HA stem showed broad activity against H1 and H5 subtypes, demonstrating the RaPID system's effectiveness. In chapter 3, in order to address resistance, the study identifies peptides that inhibit a mutant HA protein resistant to earlier inhibitors. Combining peptides forces the virus to develop mutations that compromise its fitness, suggesting a potential strategy to counteract resistance. In chapter 4, the research discovers peptide inhibitors for SARS-CoV-2. Peptide S1b3inL1 exhibits significant inhibition across multiple variants and related viruses. The peptide likely inhibits infection by stabilizing the prefusion form of the spike protein, a novel approach to counteracting the virus. This thesis highlights the potential for cyclic peptide inhibitors to target various viral fusion proteins and the importance of developing broad-spectrum inhibitors to address unpredictable viral mutations. Future work could focus on iterative selection processes, optimization techniques, and studying resistance mechanisms to enhance the clinical potential of discovered inhibitors. Overall, this research underscores the strength of the RaPID system in finding new peptide inhibitors and overcoming viral resistance, offering promising leads for further drug development.
Oordelen zonder oogkleppen
Authors:   , Duran Mehmet
Published: August 2024

Semi-public organizations play an important role in public services in the Netherlands. Citizens rely on their services throughout their lives, including healthcare, culture, childcare, education, and housing. Supervisory boards monitor the management and these organizations. It is a part-time role, non-executive directors (members of the supervisory boards) are not present daily and often depend on information from the CEO. Semi-public organizations increasingly operate in complex and dynamic environments, requiring non-executive directors to consider various interests and criteria in their decision-making. Previous studies show that supervisory boards often face challenges, especially with information provision. This makes well-informed (or high-quality) judgments by non-executive directors complex and vulnerable. This dissertation examines how non-executive directors can make well-informed judgments on important issues based on the information available. The research indicates that non-executive directors make better judgments when they also gather information themselves, leading to more diverse information. However, in practice, this often does not happen because non-executive directors tend to socialize and have a trust-based relationship with the CEO. Proactively gathering information from other sources can, in some cases, disrupt the trust-based relationship. Additionally, the study shows that confirmation bias poses a risk that can hinder well-informed decision-making. This research provides important recommendations for non-executive directors to achieve well-informed judgments through a good information process.
Exploring the Effects of Video-based Multimedia instructional strategies on students’ performance in Astrophysics in Rwandan Secondary School
Authors: Tugirinshuti Gabriel Janvier , BIZIMANA Emmanuel , NDAYISABA Alexandre , NTAGANIRA Josue Michel , UWANYIRIGIRA Alice
Published: August 2024

Now, more than ever before, innovative teaching methodology in STEM education has been a matter of concern. Previous research abounds settling the importance of technology-based methodology in STEM education. This study seeks to explore the effects of video-based multimedia (VBM) on students’ performance in astrophysics in certain scientific schools in Rwanda. The current study presents the findings of a quasi-experiment non-equivalent control group carried out from eight scientific schools where 294 students in science combination with physics as a major subject were purposively selected. Pre-test and post-test were used to collect data using an astrophysics achievement test (AAT) with a Cornbanch Alpha of 0.87. The results of the study showed the widespread effects of VBM in enhancing the students’ performance in astrophysics. The results show that also girls did marginally well compared to boys, however, special attention is needed in rural-based schools. The findings of this study offer a suggestion on the essential to integrate VBM in teaching physics.
Evli Olmayan Kişilere Üremeye Yardımcı Tedavi Yöntemlerinden Yararlanma Hakkı Tanınmamasının Hukuki Gerekçeleri Üzerine Bir Değerlendirme
Authors: Taşkın Zeynep Damla
Published: August 2024

Türk hukukunda üremeye yardımcı tedavi yöntemlerinden yararlanma hakkı sadece evli kişilere tanınmıştır. Doğal yoldan çocuk sahibi olamayan evli kişiler, birbirlerine ait üreme hücrelerini kullanarak yapay döllenme yoluyla çocuk sahibi olabilmektedir. Üremeye yardımcı tedavi yöntemlerine başvurabileceklere ve yöntemin kendisine ilişkin bu sınırlama, bugüne kadar çeşitli açılardan hukuka aykırılık iddialarına konu edilmiştir. Ancak bu iddiaları değerlendiren Danıştay, yürürlükteki miras hukuku ve soybağı hükümleri göz önünde bulundurulduğunda anılan sınırlamaların yerinde olduğuna karar vermiştir. Bu çalışmada Danıştay tarafından sunulan gerekçelerin, evli olmayan kişilerin üremeye yardımcı tedavi yöntemlerinden dışlanmasını meşru kılıp kılamayacağı irdelenmiştir. Bu sırada, elde edilmiş embriyoların eşlerden birinin ölümü üzerine imha edilmesini öngören Üremeye Yardımcı Tedavi Uygulamaları Ve Üremeye Yardımcı Tedavi Merkezleri Hakkında Yönetmelik’in 20. maddesinin ilgili kısmı hakkında verilen yürütmeyi durdurma kararı da çiftin evli olması zorunluluğu açısından değerlendirilmiştir. Çalışmanın sonunda ise, evli ve evli olmayan çiftler arasında yapılan ve meşru bir dayanağı olmayan bu ayrımın ortadan kaldırılması için yapılabilecek düzenleme tekliflerine yer verilmiştir.
Yabancı Taşıyıcı Anneden Doğan Çocuğun Türk Vatandaşlığını Kazanabilmesine İlişkin Bir Değerlendirme
Authors: Ecemiş Sercan
Published: August 2024

Tıp alanında meydana gelen teknolojik gelişmelerle birlikte, çocuğu doğuran kadının aynı zamanda o çocuğun annesi olduğunun kabulü tartışılmaya başlanmıştır. Zira bugün için tıbbi gelişmeler, çocuğu doğuran kadının aynı zamanda o çocuğun genetik olarak anne olma zorunluluğunu ortadan kaldırmıştır. Kısaca ebeveyn olmak amacıyla bir başka kadının rahminin kiralanması veya ödünç alınması şeklinde ifade edilebilecek taşıyıcı annelik, Türk hukukunda yasaklanmıştır. Buna karşın bu yasaklar, bu yolla ebeveyn olmak isteyen kişilerin bu işlemlerin hukuken mümkün olduğu diğer devletlerde bu işlemleri gerçekleştirmesine engel olmamaktadır. Bu yolla yabancı taşıyıcı anneden doğan çocuğun genetik annesinin Türk vatandaşı olması halinde, çocuğun genetik anneye bağlı olarak Türk vatandaşlığını kazanıp kazanamayacağı önemli bir sorun olarak karşımıza çıkar. Sorunun özü vatandaşlık hukukuna ilişkin olsa da bu mesele milletlerarası özel hukukun diğer alt dallarından bağımsız bir incelemenin konusunu oluşturamaz. Biz de bu çalışmada, bu soruya bir cevap verebilmek amacıyla, konumuzla bağlantılı olduğu ölçüde taşıyıcı anneliğin kanunlar ihtilafı hukuku ile milletlerarası usul hukuku boyutlarını incelemekteyiz. Bu incelemeler sonucunda varılan sonuçların, Türk vatandaşlığına olan etkisine bir cevap vermeye çalışmaktayız.
Musiki Eserlerin Telif Hakkına Dayalı Menkul Kıymetleştirme ve Bowie Tahvilleri Örneği
Authors: Karaca Büşra Gül
Published: August 2024

Müzik, sanatın sınırlarını aşarak finans sektörünün de dikkatini çeken bir odak noktası haline gelmiştir. Musiki eserlerin finansal öneminin giderek anlaşılması, onların varlığa dayalı menkul kıymetleştirme uygulamasında finansal bir varlık olarak değerlendirilmesini gündeme getirmiştir. Bu yöntemin ilk ve en çarpıcı örneğini “Bowie tahvilleri” adıyla bilinen tahviller oluşturmaktadır. Bowie tahvilleri ile ilk kez 1997 yılında musiki eserlerin telif hakları, menkul kıymetleştirme işlemine konu olmuştur. Ünlü İngiliz şarkıcı David Bowie, yirmi beş albümünden gelecekte elde edeceği telif alacaklarına dayalı olarak yapılan varlığa dayalı menkul kıymetleştirme sayesinde elli beş milyon dolar elde etmiştir. Bowie tahvilleri müzik endüstrisinde telif haklarının yenilikçi bir şekilde finanse edilebileceği gösteren etkileyici bir örnek olmuştur. Tahvillerin de gösterdiği gibi telif haklarına dayalı menkul kıymetleştirme, telif hakkı sahibine gelecekte elde edilmesi muhtemel telif gelirlerini daha önceden toplu olarak almayı sağlayarak, sermayesini artırma ve vergi avantajı elde etme imkânı sunmasının yanı sıra, yatırımcılara da farklı yatırım fırsatları sunmaktadır. Ancak telif haklarına dayalı menkul kıymetleştirme hala varlığa dayalı menkul kıymetleştirmelerin küçük bir yüzdesini oluşturmaktadır. Bunun sebepleri arasında fikri hakların değerlemesine yönelik zorluklar, fikri haklara özgü risk faktörlerinin nakit akışını tahmin etmeyi zorlaştırması ve müzik sektörünün hassas yapısından kaynaklanan sorunlar yer almaktadır.
Müzik Eserlerinin Karaoke ve Cover Versiyonlarının Sosyal Medya Ortamlarında Sunulmasının 5846 Sayılı Fikir ve Sanat Eserleri Kanunu Açısından Değerlendirilmesi
Authors: Karaaslan Pelin , Açıkgöz Ahunur
Published: August 2024

İnternet, toplumun sosyal ve kültürel hayatında oldukça önemli bir yere sahip olan fikir ve sanat eserlerine erişim imkanını ve yöntemlerini gün geçtikçe artırmakta, dönüştürmektedir. Günümüzde internet kullanıcısını aktif bir konuma taşıyan sosyal medya platformlarında bireyler aktif eylemlerini hukukun çizdiği sınırlar içerisinde gerçekleştirmek zorundadırlar. Bir fikir ve sanat eserinin sosyal medyanın “renkli dünyasına” aidiyeti bu eserleri konu alan eylemlerin hukuki sınırlarının belirlenmesini daha da önemli bir noktaya taşımaktadır. İşte dijital çağda, teknolojinin sunduğu erişilebilirlik sayesinde birçok birey, başkalarına ait müzik eserlerinin cover’larını veya karaoke versiyonlarını oluşturup sosyal medya platformlarında geniş kitlelerle paylaşmaktadır. İlk bakışta eğlenceli gözüken ve bireylerin kendi yeteneklerini ve ilgi alanlarını daha geniş bir kitleye sergileme fırsatını sağlayan bu süreç, belirli kurallara riayet edilmediği takdirde müzik eserleri sahipleri ile bağlantılı hak sahiplerinin 5846 sayılı Fikir ve Sanat Eserleri Kanunu’ndan doğan haklarının ihlaline yol açabilir. Bu makale, sözü geçen eylemlerle ilgili olarak anılan Kanun çerçevesinde hangi durumlarda ne tür hak ihlallerinin oluşabileceğini incelemeyi amaçlamaktadır.
Dijital Ürünlerin Eşya Niteliğine Disiplinlerarası Bir Bakış
Authors: Ercan Cannur , Ünlen Gökhan
Published: August 2024

Dijital ürün olarak ifade edebileceğimiz dijital içerik ve dijital hizmetler yaşamımızın, artık neredeyse her günümüzün bir parçasıdır. Öyle olmakla beraber hukukumuzda henüz bunlara ilişkin bir yasal düzenleme bulunmamaktadır. AB ülkelerindeki yasalaşma süreci ise oldukça yenidir. Dijital ürünlerin kendisinin anlamsal varlığı; sözdizimsel bakımdan kodlanmış bilgi düzeyindeki varlığı ile cd, dvd ya da bilgisayar belleği gibi herhangi bir taşıyıcıya kodlanarak kavuşacağı fiziksel dünyadaki varlığı, üçlü bir yapıyı beraberinde getirmektedir. Doktrinde ZECH’in bilginin varlık düzeyindeki sınıflandırması dijital ürüne uygulanarak; dijital ürünün varlık düzeyindeki semantik, sentaktik ve (olası) fiziksel varlığı gereği üçlü bir yapıyı bünyesinde barındırabileceğine dikkat çekilmelidir. Dijital ürünlerin bu anlamda kendine özgülüğü, bunlara gerek pozitif hukuk (de lege lata) gerek olması gereken hukuk (de lege feranda) bakımından uygulanabilecek hükümlerin belirlenebilmesinde bazı güçlükleri beraberinde getirmektedir. Çalışmada dijital ürünün hukuki niteliği perspektifinden eşya niteliği taşıyıp taşımadığına ilişkin değerlendirmelerin Telif Hukuku ve Sözleşmeler Hukuku ile ilişkilendirilerek ele alınması amaçlanmaktadır. Dijital ürünün üzerinde vücut bularak fiziksel dünyada varlık kazandığı eşya ile ilişkisi çalışmanın odak noktasını oluşturmaktadır.
THERMOMECHANICAL DEFORMATION OF CARBON NANOTUBES IN POLYMER MATRIXES
Authors:   National Transport University, Shlyun Nataliia , Zaiets Julia ,   National Transport University
Published: August 2024

Annotation: A theoretical study of the effects of nucleation of intrastructural thermal stresses in polymer materials reinforced with carbon nanotubes, caused by thermomechanical incompatibility of materials, was performed. Differential equations of its thermoelastic interaction with epoxy, polyamide, phenol-formaldehyde, polyester, polycarbonate, polystyrene, and polypropylene media in uniform and non-uniform temperature fields were constructed on the basis of modeling of a nanotube with an elastic cylindrical shell with aggregated values of thickness, modulus of elasticity, Poisson's ratio, and coefficient of linear thermal expansion. The solutions of these equations are found in closed form. The distribution functions of thermal stresses in the matrix medium and thermal forces in the nanotube wall are constructed. It was demonstrated that the thermal stresses in the matrix medium have the form of concentrators on the interface surface between the phases of the system and decrease inversely proportional to the square of the distance to the axis of the nanotube. It is shown that the intensities of these thermal stresses increase with increasing incompatibility of the thermomechanical parameters of the system phases.
CONCEPTUAL PRINCIPLES OF FORMATION OF A PORTFOLIO OF PUBLIC PARTICIPATION PROJECTS
Authors:   National Transport University, Vorkut Tatyana , Bozhok Yuliya ,   National Transport University, Petunin Andrii ,   National Transport University, Kharuta Vitaly ,   National Transport University
Published: August 2024

Abstract. The relevance of the research topic is determined by the need for improvement and further development of methodological approaches to the management of project portfolios, in terms of the formation of the latter based on the issues of public participation project management. The subject of the research is the methods, models, mechanisms and standards of project portfolio formation, considered in the context of public participation project portfolio formation. The object of research is the process of managing public participation projects. Research methodology. The research was conducted according to the practice of managing public participation projects in the territorial communities of cities - regional centers - of Ukraine, as well as the city of Kyiv in 2016–2021. The method of scientific identification and comparative analysis was used in the formation of the conceptual basis of the research, as well as in the analysis of scientific works; when developing the concept of forming a portfolio of public participation projects - abstract-logical method, case method; with the development of models for determining the optimal composition of the portfolio of public participation projects - the method of integer programming, methods of evaluating the effectiveness of investment projects, the concept of the value of money over time. Keywords: project management, project portfolio, management of project portfolios, portfolio-oriented management, public participation projects, public project, public budget.
DEVELOPMENT OF COMMUNICATION AND INFORMATION SYSTEMS OF TRANSPORT ENTERPRISES
Authors:   National Transport University, Lozhachevska Elena , Lavryk Ivan ,   National Transport University, Sedoy P. ,   National Transport University
Published: August 2024

Abstract. The article reveals the main aspects of the development of communication and information systems of the transport enterprise. The history of creation and stages of formation of communication and information systems (CIS) are studied. Based on the analysis of the author's scientific opinions, the concept of communication and information systems was formed and it was determined that it is quite broad and is understood by scientists in various variations. Therefore, on the basis of this, the main parameters of innovative communication and information systems of a modern transport enterprise are investigated in the article. The main aspect in the future was to determine the influence of intelligent intelligence on the development of the latest communication and information systems of a modern transport enterprise. The application of smart intelligence allows you to automate many routine operations and management processes at a transport enterprise. For example, AI can optimize vehicle routing, schedule planning, inventory management, which can reduce costs and improve resource efficiency. It has been proven that in modern military conditions it is important to be able to quickly react to emergency situations and changes in the situation. Developed CSIs help ensure prompt exchange of information and decision-making for effective situation management. Keywords: communications, communication and information systems, transport enterprises, development, management.
Penggunaan Media Sosial sebagai Sarana Promosi Bisnis Pasca Pandemi Covid-19
Authors: Beni Sabinus , Clara Novelni
Published: August 2024

The Covid-19 pandemic had a significant impact on various sectors, including entrepreneurial businesses. In this situation, the use of social media as a promotional tool has become increasingly important in sustaining and developing their businesses. This research aims to analyze the influence of the Covid-19 pandemic on student entrepreneurial businesses at Shanti Bhuana Institute and to explore the use of social media as a promotional tool in overcoming the challenges during the pandemic Additionally, the challenges of utilizing social media as a promotional tool need to be examined. This research adopts a qualitative approach, collecting data through in-depth interviews with a number of student entrepreneurs at Shanti Bhuana Institute. The data is analyzed using content analysis methods to identify the impacts of the pandemic and strategies for using social media. The findings indicate that the Covid-19 pandemic has had negative effects on student entrepreneurial businesses, including a decline in revenue and demand. However, the use of social media as a promotional tool provides opportunities to reach a wider audience and build customer relationships. Student entrepreneurs employ strategies such as creating engaging content, collaborating with influencers, and actively interacting with customers through social media
Analisis Pelaksanaan Bangkit Berdaya dengan Model CIPP di Kelurahan Bagan Pete Kecamatan Alam Barajo Kota Jambi
Authors: Mesya Wulan Husada  , Muhammad Nuur  , Arman Abdul Rochman
Published: August 2024

Sebagai pengimplementasian dari UU No. 23 Tahun 2014, Pemerintah Kota Jambi membuat suatu program yang dikenal dengan Bangkit Berdaya dan merupakan salah satu program unggulan yang mendapatkan penghargaan. Atas dasar ini, dalam penelitian tersebut ingin menganalisa pelaksanaan Bangkit Berdaya di Kelurahan Bagan Pete dengan mengaitkannya pada Model CIPP guna menganalisis program secara komprehensif hingga kepada faktor-faktor pendukung dan penghambatnya. Metode yang digunakan ialah Kualitatif Deskriptif dengan teknik pengumpulan datanya melalui observasi, wawancara, dan dokumentasi yang dianalisa melalui 4 cara yakni pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Dalam temuan pada penelitian yang dilakukan bahwasanya pelaksanaan Bangkit Berdaya dengan Model CIPP telah sesuai. Di mana dari sisi context adanya tujuan yang mendasari program dan kesesuaian kebutuhan dengan sasarannya. Dari sisi  input semua pihak terlibat, sesuai aturan dan prosedur, realisasi bantuan dan dana yang sesuai hinga sarana dan prasarananya tersedia. Dari sisi Process terdapat serangkaian kegiatan hingga kendala yang ditemui. Dari sisi product terdapat hasil akhir yang sesuai dan feedback masyarakat. Kemudian faktor pendukung kegiatan semua masyarakat mau dilibatkan selama pelaksanaannya dan faktor penghambatnya ialah hujan.
Analisis Pelaksanaan Pemilihan Kepala Desa Antar Waktu (PAW) di Desa Karangkemojing Kecamatan Gumelar Kabupaten Banyumas Tahun 2022
Authors: Sari Yunita Ratna , Andini Laras Ayu
Published: August 2024

Indonesia menerapkan otonomi daerah sejak tahun 2002. Dengan adanya otonomi daerah maka pemerintahan  daerah termasuk pemerintahan desa berhak menyelenggarakan pemilihan kepala desa. Ada dua model pelaksanaan pemilihan kepala desa yaitu serentak dan antar waktu (PAW). Pemilihan kepala desa serentak diselenggarakan jika jabatan kepala desa selesai dan pemilihan kepala desa antar waktu (PAW) dilakukan apabila masih ada sisa jabatan minimal 1 tahun sementara kepala desa meninggal, terlibat kasus hukum pidana atau mengundurkan diri. Salah satu desa yang menyelenggarakan PAW yaitu desa Karangkemojing sebagai desa pertama di kabupaten Banyumas yang melaksanakan pemilihan kepala desa antar waktu tahun 2022. Metode penelitian ini menggunakan kualitatif deskriptif dengan teknik pengumpulan datanya menggunakan wawancara mendalam seperti BPD Karangkemojing, Sekretaris Kecamatan Gumelar, Badan Kesatuan Bangsa dan Politik Kabupaten Banyumas, Dinas Sosial dan Pemberdayaan Masyarakat Desa Kabupaten Banyumas serta panitia  pemilihan kepala desa antar waktu Karangkemojing. Analisis data menggunakan triangulasi. Hasil penelitian ini menunjukkan bahwa pelaksanaan pemilihan kepala desa antar waktu berjalan cukup baik akan tetapi terdapat kelebihan jumlah suara ketika penghitungan suara sebanyak satu suara. Padahal total jumlah pemilih pemilihan kepala desa antar waktu di desa Karangkemojing sebanyak 68 orang akan tetapi hasil perhitungan suara sebanyak 69 suara. Rekomendasi yaitu monitoring lebih masif dari Badan Kesatuan Bangsa dan Politik Kabupaten Banyumas, Dinas Sosial dan Pemberdayaan Masyarakat Desa Kabupaten Banyumas.
Upaya Mitigasi Bencana di Indonesia: Analisis Bibliometrik dan Analisis Konten
Authors: Nurrahman Agung
Published: August 2024

Bencana merupakan fenomena yang dapat memberikan dampak yang luas bagi suatu negara. Indonesia merupakan salah satu negara yang memiliki potensi menghadapi bencana. Bencana yang dihadapi sepanjang tahun 2023 dan pada bulan Januari 2024 memberikan dampak bagi berbagai sektor di Indonesia. Untuk mengurangi risiko, dampak, dan konsekuensi dari bencana yang mungkin terjadi, dibutuhkan mitigasi bencana. Penelitian mitigasi bencana di Indonesia relatif banyak dilakukan namun penelitian yang membahas trend penelitian mitigasi bencana dengan menggunakan analisis bibliometrik dan analisis konten masih jarang dilakukan. Tujuan penelitian ini adalah untuk mengetahui tren dan fokus penelitian terkait mitigasi bencana di Indonesia. Metode analisis bibliometrik dan analisis konten diterapkan untuk mengungkapkan penekanan dan trend dalam diskursus ilmiah, dengan bantuan aplikasi VOSviewer untuk visualisasi data. Sebanyak 69 artikel yang diterbitkan dalam jurnal database Scopus berkaitan dengan mitigasi bencana di Indonesia dengan trend penelitian terbanyak pada tahun 2021 sejumlah 16 artikel. Hasil penelitian menunjukkan bahwa apabila dilihat dari distribusinya pada berbagai jurnal, jurnal dengan jumlah naskah publikasi terbanyak adalah jurnal Disaster Advances. Penulis yang memiliki jumlah sitasi terbanyak merupakan penulis dari luar Indonesia yaitu dengan 46 buah sitasi, yaitu penulis Hall, Sarah; Harris, Ron dan Meservy, William. Kata kunci yang mempunyai kejadian bersama terbanyak adalah Indonesia, disaster mitigation dan disaster management. Adapun kata kunci yang belum banyak dilakukan di dalam penelitian diantaranya yaitu sebagai berikut: disaster risk reduction, Disaster prevention, ecotourism, tourist destination, earthquake, disaster planning, disaster preparedness, landslide, community response climate change, tourist attraction, dan earthquake event. Didapatkan juga telah ada 7 (tujuh) kategori upaya penanganan mitigasi bencana di Indonesia, diantaranya yaitu pengelolaan pemetaan pariwisata di kawasan rawan bencana, peningkatan kesiapsiagaan masyarakat terhadap bencana, mitigasi struktural dan non struktural, penyebarluasan tanda-tanda peringatan dini, program pendidikan masyarakat terkait risiko bencana, pengembangan media kampanye dan sosialisasi program-program mitigasi bencana dan pelibatan masyarakat dalam menyusun kerangka kerja desain mitigasi bencana.
 
Kata Kunci: Analisis Bibliometrik, Analisis Konten, Indonesia, Manajemen Bencana, Mitigasi Bencana.
θ-Weighted mixture distribution: the Weibull-Lomax case
Authors: Carvajal-Muquillaza Cristian , Manríquez Ronald , Cabrera Eduardo
Published: August 2024

Introduction

This article introduces a new family of weighted mixture distributions, referred to as θ-WM. The θ-WM family is generated by combining two distributions weighted by a parameter θ, offering notable flexibility to model a wide range of complex phenomena. A special case study of the θ-weighted mixture distribution of Weibull-Lomax (θ-WMWLx) is included, resulting from the combination of Weibull and Lomax distributions.

Methods

The research thoroughly examines the reliability and statistical properties of the θ-WMWLx distribution. Key aspects such as stochastic dominance, survival and hazard functions, mean residual life, and moments are addressed. The maximum likelihood method is used to estimate unknown parameters.

Results

The research findings show that the θ-WMWLx distribution provides a superior fit compared to competing distributions. The analyses are validated using three real datasets, demonstrating the effectiveness of the proposed distribution.

Discussion

The θ-WMWLx distribution stands out for its ability to model complex phenomena with high precision. Validation with real data confirms that the proposed distribution offers a better fit than existing distributions, highlighting its utility and applicability in various statistical analysis contexts.
Fine-tuned protein-lipid interactions in biological membranes: exploration and implications of the ORMDL-ceramide negative feedback loop in the endoplasmic reticulum
Authors: Dingjan Tamir , Futerman Anthony H.
Published: August 2024

Biological membranes consist of a lipid bilayer in which integral membrane proteins are embedded. Based on the compositional complexity of the lipid species found in membranes, and on their specific and selective interactions with membrane proteins, we recently suggested that membrane bilayers can be best described as “finely-tuned molecular machines.” We now discuss one such set of lipid-protein interactions by describing a negative feedback mechanism operating in the de novo sphingolipid biosynthetic pathway, which occurs in the membrane of the endoplasmic reticulum, and describe the atomic interactions between the first enzyme in the pathway, namely serine palmitoyl transferase, and the product of the fourth enzyme in the pathway, ceramide. We explore how hydrogen-bonding and hydrophobic interactions formed between Asn13 and Phe63 in the serine palmitoyl transferase complex and ceramide can influence the ceramide content of the endoplasmic reticulum. This example of finely-tuned biochemical interactions raises intriguing mechanistic questions about how sphingolipids and their biosynthetic enzymes could have evolved, particularly in light of their metabolic co-dependence.
Perceptions on tailored messages from a values clarification tool: a mixed-methods study of older adults with cancer
Authors: Cole Amy C. , Kwong Elizabeth , Mhina Carl , King Andy J. , Mazur Lukasz , Richardson Daniel R.
Published: August 2024

Introduction

The purpose of this study was to assess whether varying input communication factors impacted participants’ perceived confidence, motivation, and likelihood to act (i.e., share or discuss their preferences and values with their clinician or family/caregiver) when receiving tailored communication from a values-clarification tool.

Methods

This study was conducted over a two-month period at the North Carolina Basnight Cancer Hospital. Patients with hematologic malignancies participated in evaluating three distinct messages that varied on three input communication factors.

Results

Results from this study indicate that most study participants preferred messages that were moderately direct, contained succinct question prompts, and that were empowering. Results also indicate that diverse perspectives and external influences may impact confidence and motivation toward discussing preferences with their clinicians.

Discussion

Our findings suggest the importance of validating the input communication factors within values-clarification tools before presenting results to patients and the need to evaluate potential disparities in patients’ participation toward discussing their preferences. Evidence from this study provides direction for future research efforts focused on improving shared decision-making among older adults.
Promoting institutional collaboration through a joint project-based learning course: a case study of upper secondary school and university students’ experienced relevance
Authors: Ikävalko Topias , Pernaa Johannes , Haatainen Outi , Aksela Maija
Published: August 2024

There is a great need to develop research-based models for supporting collaboration between educational institutions. Collaboration models are needed, for example, to assist the transition from lower educational level to higher education or from higher education to working life. In this research, collaboration was conducted through a joint course between upper secondary school and university, which addressed global challenges by using a project-based learning approach. There is a shortage of research exploring students’ perceptions of collaboration. Therefore, the main purpose of this qualitative case study is to explore the relevance of the joint course for upper secondary school students and university students. The research was guided by the following research question: What kind of relevance did the students experience in the joint project-based learning course? The data were gathered using questionnaires, interviews, and reflective study reports. The data were analyzed via theory-based content analysis, where research-oriented relevance model was used as the analysis framework. The analysis framework enabled categorizing experienced relevance on individual, vocational, and societal dimensions. Altogether, the analysis produced seven relevance categories for upper secondary students and nine for university students. According to the analysis, upper secondary school students felt that the course offered the most on an individual relevance dimension, whereas university students experienced the vocational relevance dimension a the most diverse. As the main conclusion, this research produced new insights on the experienced relevance of upper secondary level and higher education cooperation from the students’ point of view. The acquired knowledge can be useful for everyone developing new cross-institutional collaboration models.