bluuebunny/crossref_metadata_2025 huggingface dataset:
HIV incidence, knowledge, attitude and practices of HIV/AIDS and antiretroviral therapy use in HIV-infected patients at Debre Elias district, North West Ethiopia
Authors: Birmeka Melese , Bekele Damtew , Anteneh Megabi
Published: June 2024

Due to hotspots as development schemes that attract mobile groups, HIV/AIDS infections are the biggest health issue in communities with low awareness and safe practice, especially in smaller towns. This study examined HIV/AIDS and Antiretroviral Therapy (ART) use-related knowledge, attitude, and practice in AIDS patients. Debre Elias Health Center conducted a cross-sectional study (N=384) from June 10 to January 20, 2021. Participants were selected using systematic random sampling and interviewed using a structured questionnaire. Logistic regression calculated significance and association between dependent and independent variables. 236 (384) or 61.4% of 384 HIV patients on antiretroviral therapy were female. HIV rates increased from 2014 to 2019. Age difference was associated with patient knowledge of ART use (P=0.005). Patients’ attitudes towards HIV/AIDS and ART use were significantly correlated with age, residence, marital status, and education (P<0.001). HIV patients 25-30 were 2.2 times more likely to know about ART use. HIV patients with a degree or higher were five times more likely to support ART. HIV patients aged 14-24 with a positive ART outlook were 94% protective. HIV prevalence is rising, especially among 15 to 24-year-old women. Public protection is needed to reduce HIV transmission.
Multimodal Data-Driven Intelligent Systems for Breast Cancer Prediction
Authors: Pichai Shanmugavadivu , Kanimozhi G. , Rani M. Mary Shanthi , Riyaz N.K.
Published: June 2024

Cancer, a malignant disease, results from abnormalities in the body cells that lead to uncontrolled growth and division, surpassing healthy growth and stability. In the case of breast cancer, this uncontrolled growth and division occurs in breast cells. Early identification of breast cancer is key to lowering mortality rates. Several new developments in artificial intelligence predictive models show promise for assisting decision-making. The primary goal of the proposed study is to build an efficient Breast Cancer Intelligent System using a multimodal dataset. The aim is to to establish Computer-Aided Diagnosis for breast cancer by integrating various data.This study uses the TCGA "The Cancer Genome Atlas Breast Invasive Carcinoma Collection" (TCGA-BRCA) dataset, which is part of an ongoing effort to create a community integrating cancer phenotypic and genotypic data. The TCGA- BRCA dataset includes: Clinical Data, RNASeq Gene Data, Mutation Data, and Methylation Data. Both clinical and genomic data are used in this study for breast cancer diagnosis. Integrating multiple data modalities enhances the robustness and precision of diagnostic and prognostic models in comparison with conventional techniques. The approach offers several advantages over unimodal models due to its ability to integrate diverse data sources. Additionally, these models can be employed to forecast the likelihood of a patient developing breast cancer in the near future, providing a valuable tool for early intervention and treatment planning.
Automatic Data-Driven Classification Systems for Cardiovascular Disease
Authors: Jayaraman Muralidharan , Pichai Shanmugavadivu
Published: June 2024

Cardiovascular disease (CVD) continues to contribute significantly to preventable deaths and avoidable disability worldwide. Prediction and prevention are of utmost importance in the support of public health. Machine learning and deep learning algorithms have emerged as powerful tools to improve the accuracy of diagnosis, prognosis, and treatment of cardiovascular disease. By employing these technologies, medical professionals can gain valuable insights into the risk factors associated with CVD. The focus of this research is to classify and predict cardiovascular diseases using techniques such as support vector machines, ensemble methods, decision trees, random forests, and neural networks. The effectiveness of these algorithms is evaluated based on metrics including accuracy, sensitivity, specificity, area under the curve (AUC), and F1 score. Results show that support vector machines and ensemble methods offer superior accuracy, while neural networks exhibit higher sensitivity and specificity in predicting cardiovascular diseases.
Tea consumption and risk of all-cause, cardiovascular disease, and cancer mortality: a meta-analysis of thirty-eight prospective cohort data sets
Authors: Kim Youngyo , Je Youjin
Published: June 2024

OBJECTIVES: Tea consumption has been considered beneficial to human health because tea contains phytochemicals such as polyphenols and theaflavins. We conducted a systematic review and meta-analysis on the association between tea consumption and mortality from all causes, cardiovascular disease (CVD), and cancer to provide a quantitative assessment of current evidence.METHODS: The PubMed, Web of Science, and Scopus databases were searched through April 2024 to identify eligible studies. Random effects models were used to combine study-specific effect estimates (ESs).RESULTS: A total of 38 prospective cohort data sets (from 27 papers) with 1,956,549 participants were included in this meta-analysis. The pooled ESs of the highest versus lowest categories of tea consumption were 0.90 (95% confidence interval [CI], 0.86 to 0.95) for all-cause mortality, 0.86 (95% CI, 0.79 to 0.94) for CVD mortality, and 0.90 (95% CI, 0.78 to 1.03) for cancer mortality. In the dose-response analysis, a non-linear association was observed. The greatest risk reductions were observed for the consumption of 2.0 cup/day for all-cause mortality (ES, 0.91; 95% CI, 0.88 to 0.94) and 1.5 cup/day for cancer mortality (ES, 0.92; 95% CI, 0.89 to 0.96), whereas additional consumption did not show a further reduction in the risk of death. A plateau was observed for CVD mortality at moderate consumption levels (1.5-3.0 cup/day), but a sustained reduction in mortality risk was observed at higher intake levels.CONCLUSIONS: Moderate tea consumption (e.g., 1.5-2.0 cup/day) was associated with lower all-cause, CVD, and cancer mortality compared to no tea consumption. Further well-designed prospective studies are needed for a definitive conclusion.
Seasonal and Inter-annual Variability in the East of the Sea of Marmara Water Masses by Temperature and Salinity Time Series
Authors: Dökümcü Kubilay , Altıok Hüsne
Published: June 2024

This study mainly aims to examine the relationship between oceanographic properties and climate change in the conjunction of the Istanbul Strait (IS), specifically in the east of the Sea of Marmara (SoM) via evaluating observational temperature and salinity profiles at six stations with monthly atmospheric pressure and air temperature during the period of 1997-2010. The annual cycle of temperature and salinity of the upper and lower layers in the east of SoM have strong seasonal variation: The upper layer temperature rises during summer while decreases in winter. Conversely, the lower layer temperature is higher in winter compared to spring and summer. Additionally, salinity levels in the upper layer are higher in winter and lower in summer, whereas in the lower layer, the pattern is reversed, with lower salinity in winter and higher salinity in summer. In this context, linear trend analyzes are calculated by using monthly time series of temperature and salinity and compared with the trends of atmospheric conditions and the surrounding seas. The average temperature trend in the east of the SoM is increase of 0.067°C/y in the upper layer and increase of 0.028°C/y in the lower layer during this period. The salinity trend is increase of 0.105 psu/y in the upper layer and increase of 0.012 psu/y in the lower layer. The air temperature trend is increase of 0.086°C/y, and the air pressure trend is decrease of 0.034 mbar/y. These values closely align with those observed in the surrounding seas. The air temperature and upper layer temperatures are consistent with each other in terms of both long-term series and trend values.
Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators
Authors: Gao Ying , Liu Mei-Fang , Li Yang , Liu Xi , Cao Yu-Jie , Long Qian-Fa , Yu Jun , Li Jian-Ying
Published: June 2024

BACKGROUND

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by fibroblast proliferation and extracellular matrix formation, causing structural damage and lung failure. Stem cell therapy and mesenchymal stem cells-extracellular vesicles (MSC-EVs) offer new hope for PF treatment.

AIM

To investigate the therapeutic potential of MSC-EVs in alleviating fibrosis, oxidative stress, and immune inflammation in A549 cells and bleomycin (BLM)-induced mouse model.

METHODS

The effect of MSC-EVs on A549 cells was assessed by fibrosis markers [collagen I and α-smooth muscle actin (α-SMA), oxidative stress regulators [nuclear factor E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), and inflammatory regulators [nuclear factor-kappaB (NF-κB) p65, interleukin (IL)-1β, and IL-2]. Similarly, they were assessed in the lungs of mice where PF was induced by BLM after MSC-EV transfection. MSC-EVs ion PF mice were detected by pathological staining and western blot. Single-cell RNA sequencing was performed to investigate the effects of the MSC-EVs on gene expression profiles of macrophages after modeling in mice.

RESULTS

Transforming growth factor (TGF)-β1 enhanced fibrosis in A549 cells, significantly increasing collagen I and α-SMA levels. Notably, treatment with MSC-EVs demonstrated a remarkable alleviation of these effects. Similarly, the expression of oxidative stress regulators, such as Nrf2 and HO-1, along with inflammatory regulators, including NF-κB p65 and IL-1β, were mitigated by MSC-EV treatment. Furthermore, in a parallel manner, MSC-EVs exhibited a downregulatory impact on collagen deposition, oxidative stress injuries, and inflammatory-related cytokines in the lungs of mice with PF. Additionally, the mRNA sequencing results suggested that BLM may induce PF in mice by upregulating pulmonary collagen fiber deposition and triggering an immune inflammatory response. The findings collectively highlight the potential therapeutic efficacy of MSC-EVs in ameliorating fibrotic processes, oxidative stress, and inflammatory responses associated with PF.

CONCLUSION

MSC-EVs could ameliorate fibrosis in vitro and in vivo by downregulating collagen deposition, oxidative stress, and immune-inflammatory responses.
Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy
Authors: Zhu Lin , He Lu , Duan Wu , Yang Bo , Li Ning
Published: June 2024

BACKGROUND

Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease that affects premature infants. Although mounting evidence supports the therapeutic effect of exosomes on NEC, the underlying mechanisms remain unclear.

AIM

To investigate the mechanisms underlying the regulation of inflammatory response and intestinal barrier function by umbilical cord mesenchymal stem cell (UCMSCs) exosomes, as well as their potential in alleviating NEC in neonatal mice.

METHODS

NEC was induced in 5-d-old C57BL/6 pups through hypoxia and gavage feeding of formula containing lipopolysaccharide (LPS), after which the mice received human UCMSC exosomes (hUCMSC-exos). The control mice were allowed to breastfeed with their dams. Ileal tissues were collected from the mice and analyzed by histopathology and immunoblotting. Colon tissues were collected from NEC neonates and analyzed by immunofluorescence. Molecular biology and cell culture approaches were employed to study the related mechanisms in intestinal epithelial cells.

RESULTS

We found that autophagy is overactivated in intestinal epithelial cells during NEC, resulting in reduced expression of tight junction proteins and an increased inflammatory response. The ability of hUCMSC-exos to ameliorate NEC in a mouse model was dependent on decreased intestinal autophagy. We also showed that hUCMSC-exos alleviate the inflammatory response and increase migration ability in intestinal epithelial cells induced by LPS.

CONCLUSION

These results contribute to a better understanding of the protective mechanisms of hUCMSC-exos against NEC and provide a new theoretical and experimental foundation for NEC treatment. These findings also enhance our understanding of the role of the autophagy mechanism in NEC, offering potential avenues for identifying new therapeutic targets.
Using Dried Blood Spots to Quantitatively Detect Anti–SARS-CoV-2 IgG Antibodies by ELISA: A Validation Study
Authors: Ylade Michelle , Aziz Asma Binte , Daag Jedas Veronica , Crisostomo Maria Vinna , Agrupis Kristal-An , Maronilla Maria Angela , Sye Lim Hong Chloe , Kim Hwa Young , Njau Irene , Lopez March Helena Jane , Deen Jacqueline , Kim Deok Ryun , You Young Ae , Kang Sophie S. Y. , Marks Florian , Tadesse Birkneh Tilahun
Published: June 2024

SARS-CoV-2 serological testing is useful to determine seroprevalence, epidemiological trends, and the extent of transmission. The collection and transport of serum samples can be logistically challenging, especially in remote underserved areas. Dried blood spots (DBSs) would allow easier sample collection and logistical handling compared with standard serum collection, particularly for extensive and repeated SARS-CoV-2 serosurveys. We evaluated the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the IgG ELISA (Wantai, Beijing, China) using DBSs against sera for the quantitative detection of SARS-CoV-2 IgG antibody. The IgG ELISA was used to test paired sera and DBSs obtained from individuals with recent virologically confirmed COVID-19 illness and banked paired sera and DBSs collected before the COVID-19 pandemic. We found that 100/100 (100%) seropositive samples were positive using DBSs, and 193/194 (99%) seronegative samples were negative using DBSs. Compared with sera, the DBS method had a 100% sensitivity, 99% specificity, 99% PPV, and 100% NPV. Use of DBSs for SARS-CoV-2 household or population serosurveys may be considered in situations with limitations in sample collection, shipment, and storage.
Gamma-Irradiated Female Aedes aegypti Mosquitoes Exhibit Greater Susceptibility to Mayaro Virus
Authors: Trefry Stephanie V. , Aldridge Robert L. , Sprague Thomas R. , Lowen Robert G. , Erasmus Jesse H. , Pitt Margaret L. , Hahn Daniel A. , Nasar Farooq , Gibson Seth , Linthicum Kenneth J.
Published: June 2024

Mayaro virus (MAYV) is an alphavirus endemic in many parts of Central and South America transmitted to humans by Aedes aegypti. Currently, there is no vaccine or treatment of Mayaro infection, and therefore it is essential to control transmission by reducing populations of Ae. aegypti. Unfortunately, Ae. aegypti are extremely difficult to control with traditional integrated vector management (IVM) because of factors such as growing resistance to a dwindling list of registered insecticides and cryptic immature and adult habitats. The sterile insect technique (SIT) by irradiation is gaining traction as a novel supplemental tool to IVM. The SIT is being used operationally to release large numbers of sterilized colony-reared male mosquitoes in an intervention area to overwhelm females in the natural population, eventually causing population decline because of high frequencies of unfertilized eggs. However, little is known about the effect of irradiation on vector competence for mosquito-borne viruses such as MAYV in females that may be accidentally reared, irradiated, and released alongside males. In this investigation, we exposed female Ae. aegypti pupae to radiation and evaluated vector competence after inoculation with MAYV. Infection and dissemination rates of irradiated (10 and 40 Gy) Ae. aegypti were higher than those of non-irradiated cohorts at 7 and 14 days after infection. Although these results indicate a need to maintain effective sex sorting prior to irradiation and release of Ae. aegypti, our results are consistent with several previous observations that vectorial capacity and vector competence are likely lower in irradiated than in nonirradiated females.
Results of Integrated Transmission Assessment Surveys for Lymphatic Filariasis and Malaria in Haiti, 2017–2022
Authors: Désir Luccène , Hamre Karen E. S. , Beau De Rochars Valéry Madsen , Lemoine Jean F. , Telfort Marc-Aurèle , Noland Gregory S.
Published: June 2024

Haiti is endemic for lymphatic filariasis (LF) and malaria, two mosquito-transmitted parasitic diseases targeted for elimination. The World Health Organization recommends a transmission assessment survey (TAS-1) to determine if LF prevalence is significantly beneath putative transmission thresholds (<2% antigen prevalence in Haiti, where Culex is the primary vector for Wuchereria bancrofti) to stop mass drug administration (MDA). Repeated TASs (TAS-2 and TAS-3) are recommended at 2–3-year intervals during post-treatment surveillance. From 2017 to 2022, The Carter Center assisted the Haitian Ministry of Public Health and Population in conducting 15 TASs in 11 evaluation units (EUs) encompassing 54 of the country’s 146 districts. Children 6–7 years old were assessed for circulating filarial antigen (CFA) by Filariasis Test Strip: n = 5,239 in TAS-1; n = 11,866 in TAS-2; and n = 1,842 in TAS-3, of whom eight (0.15%), 20 (0.17%), and eight (0.43%) tested positive, respectively. The number of positive results in children was less than the threshold in each EU. When available, participants (n = 16,663) were also tested for malaria by rapid diagnostic test, with 31 (0.19%) children testing positive for Plasmodium falciparum. Integrated TASs provided an efficient means to collect epidemiological data for LF and malaria in Haiti. Results indicated thresholds for stopping and maintaining the halt of MDA for LF have been achieved in all EUs, with the halt of MDA for 571,358 people in four districts and the first TAS-3 surveys conducted in Haiti. Investigations are needed to assess the potential of ongoing LF transmission, especially in areas where CFA-positive samples were detected in TAS-3.
Trends in the Prevalence of Antimicrobial Resistance in Escherichia coli Isolated from Outpatient Urine Cultures in French Amazonia
Authors: Nkontcho Djamkeba Flaubert , Sainte-Rose Vincent , Lontsi Ngoulla Guy Roger , Roujansky Ariane , Abboud Philippe , Walter Gaelle , Houcke Stephanie , Demar Magalie , Kallel Hatem , Pujo Jean Marc , Djossou Felix
Published: June 2024

Antimicrobial resistance (AMR) in the community is increasing worldwide. We aimed to assess AMR trends in Escherichia coli from the community urine isolates in French Amazonia. We conducted a retrospective study from January 2016 to December 2022 in the Cayenne General Hospital microbiology laboratory (French Guiana). It included all urine samples positive for E. coli collected from adult outpatients. During the study period, 3,443 urinalyses positive for E. coli were studied. In 46% of cases, patients were women. In 64.4% of cases, E. coli were β-lactamase producers. The most frequently diagnosed resistance mechanisms were penicillinase production and sparing third-generation cephalosporins. Isolated E. coli were extended-spectrum β-lactamase (ESBL) producers in 6.1% of cases. Overall, E. coli was susceptible to amoxicillin in 35.9% [95% CI: 34.3–37.5], to amoxicillin/clavulanic acid in 62.2% [95% CI: 60.6–63.9], to cefotaxime in 94% [95% CI: 93.1–94.7], to gentamicin in 92.1% [95% CI: 89.1–92.6], to ofloxacin in 76.8% [95% CI: 75.3–78.2], to trimethoprim/sulfamethoxazole (SXT) in 58.8% [95% CI: 57.1–60.5], to fosfomycin in 99.1% [95% CI: 98.6–99.4], and to nitrofurantoin in 99% of cases [95% CI: 98.6–99.3]. We have observed a gradual decline in the susceptibility profile of E. coli for amoxicillin/clavulanic acid (P <0.001), piperacillin/tazobactam (P = 0.003), and temocillin (P = 0.006). However, susceptibility to ciprofloxacin was increasing (P = 0.001). In contrast, the susceptibility trends for amoxicillin, third-generation cephalosporins, gentamicin, SXT, nitrofurantoin, and fosfomycin remained stable over the 28 quarters of the study. In conclusion, isolated E. coli from outpatient urinalyses showed increased resistance profiles involving penicillinase and ESBL production. Close monitoring and strategies to decrease antibiotic consumption in the community are needed.
Case Report: Salmonella typhi Iliopsoas Abscess with Concomitant Sacroiliitis in a Young Immunocompetent Male: A Rare Case
Authors: Kumar Bhuvanesh , Agarwal Dipasha , Meena Durga Shankar , Kumar Deepak , Sureka Binit
Published: June 2024

Iliopsoas abscess is an infrequent condition characterized by the collection of pus in the iliopsoas compartment. The prevalence of the disease has been increasing in recent years with the emergence of various comorbidities and risk factors. The availability of newer imaging modalities has also improved the detection of new cases. Salmonellosis is an uncommon etiology in iliopsoas abscess and sacroiliitis. Most cases reported in the literature are associated with Staphylococcus aureus, Streptococci species, and Escherichia coli. Diabetes, hematological malignancies, HIV, and other immunocompromised states are important comorbidities/risk factors for iliopsoas abscess. We report a case of an 18-year-old male who presented with a history of fever and right hip pain for 10 days. Radioimaging revealed right sacroiliitis and iliopsoas abscess. Blood culture revealed pan-sensitive Salmonella typhi. After the prolonged course of antibiotics (intravenous ceftriaxone followed by oral levofloxacin), the patient improved with no further relapse in symptoms. Salmonella typhi should be an important differential of iliopsoas abscess in endemic regions after ruling out the common etiology such as S. aureus and Mycobacterium tuberculosis.
Bacteriological and Serological Investigation of Leptospirosis in Dogs and Pigs in Palau
Authors: Suzuki Ryo , Suzuki Sayaka , Sato Obak Sherman , Alfonso Rush , Kitalong Christopher , Nwe Yin Yin , Takabe Kyosuke , Morita Masatomo , Akeda Yukihiro , Koizumi Nobuo
Published: June 2024

Leptospirosis is a zoonotic disease caused by the pathogenic spirochaetes of the genus Leptospira. It is a public health concern in the Pacific Islands and is considered endemic in Palau. However, information on the genotypes and serotypes of causative Leptospira spp. in the country is limited. In this study, we isolated leptospires and detected antileptospiral antibodies in dogs and pigs. The isolates were characterized using a serological method and whole-genome sequencing. Leptospira interrogans was isolated from five of the 20 symptomatic dogs and one of the 58 healthy pigs. Their serogroups were identified as Icterohaemorrhagiae and Pyrogenes; however, the serogroup of one isolate could not be determined. Anti-Leptospira antibodies were detected in 14.4% (26/181) of the dogs and 20% (10/50) of the pigs. The reactive serogroups in dogs and pigs were almost identical, except for the Panama serogroup. Core genome multilocus sequence typing revealed that five of the six core genome sequence types (cgSTs) were newly identified in this study. The cgSTs from the serogroup Icterohaemorrhagiae isolates belonged to the same group as the Copenhageni and Icterohaemorrhagiae serovars isolated in other countries, whereas no similar cgSTs were identified in the Pyrogenes or unidentified serogroup strains. We demonstrated a high incidence of canine and porcine leptospirosis and identified new L. interrogans genotypes (cgSTs) circulating in Palau. Further investigations are needed to determine whether dogs and pigs serve as maintenance hosts for newly identified L. interrogans genotypes and whether they pose a risk of leptospirosis transmission to humans.
Professional Inquiry as a Strategy for Language Teacher Development
Authors: Borg Simon , Soltyska Anna , Oldfield-Mariano Melissa , Davis Alan , Friedel Ablanedo Beatriz , Salas Fernandez Paula
Published: June 2024

Von Oktober 2022 bis März 2023 führte das Zentrum für Fremdsprachenausbildung (ZFA) der Ruhr-Universität Bochum ein Programm zur beruflichen Weiterbildung seiner Lehrkräfte durch. Dieser einleitende Artikel stellt Professional Inquiry (professionelle Unterrichtsuntersuchung) als eine Strategie für die Entwicklung von Lehrkräften vor und beschreibt die Prinzipien, die ihr und somit auch dem ZFA-Projekt zugrunde liegen. Überdies wird im Folgenden ein Überblick über die drei von den Lehrkräften des ZFA durchgeführten Projekte gegeben und dargelegt bzw. erläutert, welchen Nutzen das Projekts für die Lehrkräfte hatte und welchen Herausforderungen sie dabei begegnet sind. Im Anschluss an diesen einleitenden Teil werden die vollständigen Berichte der teilnehmenden Lehrkräfte vorgestellt. Diese Berichte zeigen, wie systematische Unterrichtsuntersuchungen von Lehrenden ihr Verständnis vom Lehren und Lernen vertiefen können. Die Erfahrungen dieses Projekts am ZFA zeigen, dass die professionelle Unterrichtsuntersuchung ein praktikabler Ansatz für die Entwicklung von Sprachlehrern an Universitäten ist.
Comparative Analysis of Embedded Operating Systems: A Criteria-Based Evaluation
Authors: Sanika More  , Shivam Mukhede  , Mrs. Minal Deshmukh
Published: June 2024

Nowadays, the Internet of Things (IoT) encompasses a wide range of applications, including smart home systems, healthcare devices, smart parking systems, and smart transportation solutions. For these types of IoT applications, embedded operating systems play a crucial role by providing excellent real-time performance and reliability. The important purpose of this system is to efficiently perform specific tasks. This paper provides a quantitative and qualitative analysis of embedded operating systems. The study in this paper focused on a selection of systems commonly utilized in industrial and academic environments. We evaluated embedded operating systems like Linux, Android, QNX, FreeRTOS, TinyOS, PalmOS, Ubuntu, LiteOS, VxWorks, and Integrity based on specific criteria. It will help industries and academics select embedded operating systems according to requirements for performing specific tasks.
Attachment style, Perceived social support And Coping strategies among
Young Adults
Authors: Ashnamol M U  , Gopika Das. S  , Varsha V  , Jikku Mariam John
Published: June 2024

Attachment style is the characteristic way people relate to others in the context of intimate relationships, which is heavily influenced by self-worth and interpersonal trust. Perceived social support refers to how individuals perceive friends, family members and others as sources available to provide material, psychological and overall support during times of need. Coping strategies typically involve a conscious and direct approach to problems, in contrast to defence mechanisms. The main purpose of the study is to analyse the significant relationship between attachment style, perceived social support and use of various coping strategies among young adults. The sample consisted of 100 young adults of age range 1826, out of which 50 males and 50 were females were collected from Kottayam district. For measuring the above mentioned variables , the scales were used a detailed information schedule was given followed by: Measure of attachment qualities by Carver , C.S for measuring attachment style ; Multidimensional scale for perceived social support by Gregory D. Zimet, Nancy W. Dahlem, Sara G. Zimet, and Gordon K. Farley for measuring perceived social support and the last scale I s Brief cope ,The Brief-Cope was developed as a short version of the original 60-item cope scale (Carver et al., 1989). The statistical analysis will be done using SPSS. and Spearman’s correlation test. The results will be mentioned in the full paper.
The impact of colour and shape in Indian social awareness advertisements on social media
Authors: Harsh Mehta  , Dr. Preeti Yadav
Published: June 2024

Advertising has evolved into a potent instrument for raising social consciousness in the age of social media. Social media platforms have evolved as an important medium for advocating social concerns in India due to its broad reach and ability to attract varied audiences. The purpose of this research is to investigate the impact of colour and shape in Indian social awareness commercials on social media, and how these visual aspects influence audience perceptions and behaviours. Colour is important in advertising because it elicits emotions and influences people's cognitive processes. Specific colours are carefully employed in Indian social awareness commercials to express messages and gain attention. The study looks at how hues like red, which represents urgency, and green, which represents optimism and positivity, are used to effectively express the intended social message. Additionally, the shape of materials within adverts might influence viewer impressions. The study digs into how these shapes are used to provoke various emotions and boost the impact of the social message, whether it is a circular shape advocating inclusivity or a triangular form symbolising strength. It investigates how shapes might generate visual clues that appeal with Indian audiences, evoking empathy and encouraging them to act.
This study's findings will help us understand the role of colour and shape in Indian social awareness commercials on social media. It will help advertisers and social media marketers create effective campaigns that appeal with Indian people. Furthermore, it will shed light on the potential of social media platforms in India to serve as catalysts for social change and awareness.
Potensi dan Peluang Implementasi Ik-Cepa terhadap Perluasan Akses Pasar Perdagangan Barang dan Jasa Indonesia Dipasar Korea Selatan
Authors: Purwanto Anto
Published: June 2024

The Indonesia-Korea Comprehensive Economic Partnership Agreement (IK-CEPA) is a bilateral free trade agreement (FTA) between Indonesia and South Korea which covers the areas of trade in goods, services, investment, economic, legal and institutional cooperation. The aim of this research is to analyze the impact of IK-CEPA implementation on trade in goods and services between Indonesia and South Korea. This study used qualitative research methods. The data collection technique in this research is literature study. The data that has been collected is then analyzed in three stages, namely data reduction, data presentation and drawing conclusions. The research results show that the implementation of IK-CEPA has influenced trade in goods and services between Indonesia and South Korea, which has led to increased trade, investment, technological progress and cooperation between the countries. However, there are still several obstacles that need to be overcome to maximize the benefits of IK-CEPA, including a lack of information about IK-CEPA among entrepreneurs and limited production capacity in Indonesia.
Faith-Based Participation in Natural- Resource Governance: Communities Defending Life and Territories in Brazil, Colombia, and Mexico
Authors: Deneulin Séverine , Lacerda Luiz Felipe , Barrera Maria , Téllez Araceli , Reddin Carrick , Zepeda Carlos , Warman Javier , Rodríguez Sarai , Buzati Jordano , Saavedra Pamela
Published: June 2024

The World Resources Institute and the Laudato Si' Research Institute, Campion Hall, University of Oxford, in partnership with local researchers and communities in Brazil, Colombia and Mexico explore how religious actors shape strategies to find peaceful resolutions to socio-environmental disputes in their regions.
Theory of Literature and Aesthetics
Authors: Jrbashyan Ashkhen
Published: June 2024

The textbook studies the connection between literature and general concepts and problems of aesthetics, highlights the place of literature among other types of arts and notes their similarities and differences. An overview of the historical development of aesthetic teachings from the Ancient world to modern theories is presented in the book. Separate sections are dedicated to the aesthetic theories and concepts of prominent philosophers (Socrates, Plato, Aristotle, Boileau, Lessing, Kant, Hegel, etc.). The integral connection between the main philosophical and aesthetic trends and the theory of literature is revealed through the course of studies. Literary movements (Classicism, Romanticism, Realism, Symbolism, Naturalism, Futurism, Expressionism, Existentialism, etc.) are observed both in a literary-historical and aesthetic context. Various art and literary schools and methodological trends of the 19th-20th centuries are presented: mythological, neo-mythological, cultural-historical, psychological, historical-comparative, etc. The main aesthetic categories (Beauty, Sublime, Tragic, Comic, etc.), their manifestation in literature and other forms of art are considered. The last chapter is of a purely literary, theoretical nature, as it covers the principles of literary types and genres differentiation, the characteristic features of epicism, lyricism and drama, and the forms of their epitomizing in art. The textbook can be useful not only for students, but also for specialists who are engaged in the field of literary theory and aesthetics issues.
Methodical Manual of French pronunciation
Authors: Meliksetyan Roza
Published: June 2024

The manual is intended for students of foreign language faculties of universities studying French as a primary or second professional language. It assumes prior knowledge of a foreign language.
Meningkatkan Visibilitas Merek untuk Warung Makan di Indonesia melalui Pelatihan Fotografi dan Pembuatan Katalog Digital
Authors: Ramadhani Nafianto , Febriana Poppy
Published: June 2024

Penelitian ini mengeksplorasi implementasi program pelatihan tentang e-commerce dan pembuatan katalog online untuk Usaha Mikro, Kecil, dan Menengah (UMKM) di Desa Tebel untuk meningkatkan jangkauan pasar dan nilai ekonomi mereka melalui platform digital. Mengenali kesenjangan signifikan dalam literasi digital dan keterampilan pemasaran online di antara pemilik usaha lokal, penelitian ini bertujuan untuk membekali mereka dengan alat dan pengetahuan yang diperlukan untuk branding online yang efektif dan presentasi produk. Metode yang digunakan melibatkan sesi pelatihan praktis yang berfokus pada dasar-dasar e-commerce, katalogisasi online, dan fotografi produk, yang dilakukan pada tanggal 24 Juni dan 1 Juli 2023. Hasilnya menunjukkan peningkatan yang signifikan dalam pemahaman peserta tentang pemasaran online, kemampuan mereka untuk membuat katalog produk yang menarik secara visual, dan efektif menggunakan platform e-commerce. Inisiatif ini tidak hanya memperluas akses pasar mereka tetapi juga memperkuat branding mereka, yang sangat penting untuk diferensiasi kompetitif dan pertumbuhan ekonomi dalam lanskap pasar yang didigitalisasi.
Analisis Ruang Henti Khusus Kendaraan Sepeda Motor Pada Simpang Jalan Jendral Sudirman-Gatot Subroto Kabupaten Pemalang
Authors: Anjarwati Sulfah , Sari Cremona Ayu Novita
Published: June 2024

Faktor penting untuk mencapai sistem prasarana transportasi darat yang baik adalah kemampuan dari suatu jalan dalam melayani arus lalu lintas, khususnya kemampuan dari suatu simpang sebagai salah satu bagian dari suatu sistem jalan secara   keseluruhan.   Sehingga   salah   satu   prasarana   yang   dibangun   oleh pemerintah adalah zona Ruang Henti Khusus (RHK) sesuai dengan surat edaran Menteri Pekerjaan Umum dan Perumahan Rakyat Nomor 52/SE/M/2015 tentang Pedoman Perancangan Ruang Henti Khusus (RHK) Sepeda Motor pada simpang bersinyal di kawasan   perkotaan. Untuk mengetahui jumlah kendaraan sepeda motor pada RHK  yang  akan  direncanakan,  maka aspek  pertama yang  harus diketahui  yaitu  luas  lengan  jalan  yang  akan  dibuat  RHK.  Jalan  Jenderal Sudirman - Gatot Subroto terletak di kabupaten pemalang,merupakan simpang yang cukup ramai karena dekat dengan pusat perbelanjaan.Tujuan dari penelitian ini   untuk   mengetahui   kinerja   simpang   tanpa   adanya   RHK,   serta   untuk mengetahui dimensi Ruang Henti Khusus (RHK) kendaraan sepeda motor yang sesuai dengan kondisi persimpangan tersebut.Dalam penelitian ini,perencanaan Ruang Henti Khusus (RHK) menggunakan metode PKJI2014,dan pedoman perencanaan  RHK  dari  Kementrian  PUPR  2015.  Dari  hasil  penelitian  di lapangan, kinerja simpang tanpa adanya RHK di peroleh derajat kejenuhan pendekat selatan (Jalan Gatot Subroto ke jalan sudirman) 0,287, sedangkan untuk pendekat timur (jalan jendral sudirman ke jalan jendral sudirman 0,313, pendekat barat 0,379 (jalan jendral sudirman ke jalan gatot subroto. Makan nilai derajat kejenuhan terhadap simpang yang di dapat sebesar <0,85 sebelum adanya RHK. Lalu untuk hasil rata rata jumlah sepeda motor yang terhenti pada  lampu merah maka perencanaan dimensi RHK rata rata penumpukan sepeda motor 15-20 unit.
OSMANLI HUKUKUNDA KADINA YÖNELİK ŞİDDETİN ÖNLENMESİ BAĞLAMINDA ŞARTLI TALAK
Authors: Zorlu Süleyman Emre
Published: June 2024

Şiddet hemen her millette ve toplulukta görülen son derece yaygın bir olgudur. Kişi, sokakta, okullarda, iş yerinde, ev içerisinde hemen her yerde fiziksel, psikolojik, duygusal ve ekonomik şiddete maruz kalabilir. İslam ahlakı şiddet toplumunu ve şiddete dayalı her türlü düzeni kabul etmemekte, sevgi ve saygıya dayalı erdemli bir toplum inşasını gerekli kılmaktadır. Sevgi ve saygıya dayalı olmayan her türlü ilişki, insan psikolojisine zarar vermekte ve amaçlanan erdemli, başarılı, sağlıklı ve saygın birey hedefine ulaşılamamaktadır. İslam hukuk sisteminin uygulandığı Osmanlı Devleti’nde şiddete dayalı aile düzeni içerisinde bulunan kadınların kaderlerine terk edilmediği, çeşitli hukuki araçlarla korunmaya çalışıldığı şeriyye sicillerinden anlaşılmaktadır. Bu hukuki araçlardan bir tanesi de şartlı talak kurumudur. Osmanlı Devleti’nde Kadı marifetiyle veya aile içerisinde fiziksel şiddet eyleminin tekrarı halinde karısının kendisinden boşanmış olacağı şeklinde alınan şartlar veya ekonomik şiddet halinde boşanmaya ilişkin yetkinin devredilmesine ilişkin alınan şartlar şartlı talaka işaret etmektedir. Şartlı talak kurumunun aile içi şiddetin önlenmesi bağlamında son derece etkin olarak kullanılan bir özel hukuk kurumu olduğu görülmektedir.
PHENOTYPIC DIVERSITY IN Calendula officinalis L. REGARDING PLANT GROWTH, PHOTOSYNTHETIC TRAITS, FLOWER YIELD, AND OIL CONTENT
Authors: Salomé-Abarca Luis Francisco , González Hernández Víctor Arturo , Soto-Hernández Ramón Marcos , Ramírez-Ramírez Iván , Cruz-Huerta Nicacio
Published: June 2024

Pot marigold (Calendula officinalis L.) is an annual herb-shrub distributed worldwide. It possesses multiple therapeutic applications as an antimicrobial, antioxidant, antiviral, anti-inflammatory, anti-cancer, and cosmetic agent. Despite its importance, its physiological traits, including photosynthetic parameters, plant growth kinetics, and oil content variation among phenotypes, remain unknown. Five contrasting phenotypes (S1 to S5), derived from a single variety, were characterized. Physiological variables evaluated included plant growth kinetics, growth rate indexes, A-Ci response curves, flower and oil yield, and oil chemical composition across eight harvesting dates. Phenotype S1 yielded the highest biomass because of its extended acceleration and deceleration growth stages during a longer period. Phenotype S1 also produced higher yields of harvested flowers and essential oil. Phenotype S2 also showed a high content of essential oils. This phenotypic diversity found in a single variety of pot marigold could be used for breeding this crop; for example, the crossing of S1 x S2 may produce F1 progenies with improved growth rates, flower yields, photosynthetic rates, and essential oil yield. Besides, phenotype S1 could be used directly for commercial planting.
Green Disclosure and Innovation to Corporate Loan: Case of LQ45 Index Companies
Authors:   School of Business and Management, Institut Teknologi Bandung Jl. Ganesa No. 10, Bandung, Indonesia, Pendyala Srinivas , Nainggolan Yunieta Anny ,   School of Business and Management, Institut Teknologi Bandung Jl. Ganesa No. 10, Bandung, Indonesia
Published: June 2024

Following the Paris Agreement on Climate Change, Indonesia committed to reducing greenhouse gas emissions by 29% through its own efforts and 49% with international support. To achieve this, the Indonesian government is advancing sustainable finance, as mandated by the 1945 Constitution, which ensures the right to a proper environment and sustainable economic principles. Supported by the Financial Services Authority (OJK), Indonesia introduced regulations like POJK No.51/POJK.03/2017 and POJK 60/POJK.04/2017, requiring financial institutions to adopt sustainable finance principles and develop environmentally friendly securities. Commercial banks must submit a Sustainable Finance Action Plan (RAKB) and sustainable reports to OJK, with green credit being a key component.This study employed a quantitative approach to examine the relationships between Green Credit Policy, corporate access to bank loans, environmental disclosure, and green innovation in Indonesian commercial banks. The analysis of historical data revealed that the Green Credit Policy significantly influenced corporate loan accessibility. Companies with robust environmental disclosures and a history of green innovation also experienced better loan acquisition outcomes.
A Study on Dispersion Characteristics for Inverted Microstrip Lines
Authors:   Department of Physics, Dum Dum Motijheel College, West Bengal State University, India, Biswas Kuntal , Dhal Lakshman ,   Department of Physics, Dum Dum Motijheel College, West Bengal State University, India, Haldar Bidyut ,   Department of Physics, Dum Dum Motijheel College, West Bengal State University, India
Published: June 2024

Inverted microstrip lines are studied for their dispersion characteristics for three different values of permittivity of the substrate using Galerkin Technique in Spectral Domain. This structure is very much useful as the current strip is attached at the lower surface of the dielectric substrate. Therefore it is rarely exposed to the outer medium results no effect due to external hazards and almost zero possibility to expose to electro- magnetic interference. Basis functions for the unknown strip current are chosen according to the ones specified in [1]. Basis functions in [1] were for slot magnetic currents and consequently they are modified for the particular problem by considering the modified boundary conditions for Maxwell’s field equations for this structure. For the theoretical development the Fourier transformation of the basis functions from space domain to spectral domain are considered. Variation of effective permittivity with available dielectric thickness has also been studied and the result shows a saturating tendency with increase in dielectric thickness.
Drying Kinetics of Grated Ginger (Zingiber officinale) In a Microwave Oven with Control of Power
Authors:   Universidad Autónoma Metropolitana, Azcapotzalco, Av. San Pablo No 420, Col. Nueva el Rosario, Alcaldía Azcapotzalco, CP. 02128, CDMX., López Raymundo , Vaca Mabel ,   Universidad Autónoma Metropolitana, Azcapotzalco, Av. San Pablo No 420, Col. Nueva el Rosario, Alcaldía Azcapotzalco, CP. 02128, CDMX., Lizardi Arturo ,   Universidad Autónoma Metropolitana, Azcapotzalco, Av. San Pablo No 420, Col. Nueva el Rosario, Alcaldía Azcapotzalco, CP. 02128, CDMX.
Published: June 2024

The drying of ginger in Mexico is not commercially done, which causes a large amount of product that is not consumed in the form of fresh vegetable, to be wasted. To obtain a more sustainable and profitable presentation of the product, it was proposed to analyze the drying kinetics and the time consumed to perform this operation, having as quality parameters the organoleptic properties, namely, color, taste and smell. The kinetics of the drying of grated ginger (Zingiber officinale) was analyzed. A microwave oven with power values of 15 and 20 W/ g of product, was used. This energy was lower than that required by other drying methods, the periods of time used were 35 min for 20 W/g and 45 min for 15 W/g. The numerical model that best represents the kinetics was the exponential one. The color variations at the end of the process were greater for the power of 15 W/g, which turned into a product of acceptable appearance, the taste was slightly more acidic, but the smell lasted very little.
Desigualdades de rendimento por gênero no mercado de trabalho artístico-cultural brasileiro
Authors:   , Gomes Glenda Nunes
Published: June 2024

Embora se acredite que a produção de conteúdos artístico-culturais envolva a liberdade e a diversidade, o que se observa é um mercado de trabalho marcado por desigualdades de gênero, raça e classe social. Essas desigualdades se manifestam, principalmente, na sub-representação de alguns grupos no setor e na diferenciação de rendimentos entre os grupos. Ao considerar especificamente o grupo das mulheres, há evidências de sub-representação feminina no setor artístico-cultural, especialmente nas ocupações de criação e performance, além das dificuldades de progressão na carreira e, algumas vezes, rendimentos mais baixos que dos homens. Ressalta- se, ainda, que vários estudos já realizados comprovam a discriminação de rendimento enfrentada por mulheres no mercado de trabalho em geral e em alguns setores específicos. A partir desta compreensão, a presente pesquisa buscou averiguar a existência de discriminação de rendimento por gênero no setor artístico-cultural brasileiro. Para tal análise, empregou-se a decomposição de Oaxaca-Blinder, a fim de verificar a existência de diferencial de rendimentos entre homens e mulheres no setor e identificar se parte desse diferencial se atribui à discriminação por gênero. A decomposição foi realizada em dois modelos distintos, considerando os possíveis efeitos dos outliers, dado que o setor artístico-cultural apresenta grande variabilidade de rendimentos. Os resultados obtidos na pesquisa apontam para desigualdade de rendimentos favorável aos homens em 2018 e a parte deste diferencial atribuída à discriminação foi de 14,57% e 5,56%, nos dois modelos, respectivamente. Em 2015, os resultados sugerem desigualdade de rendimentos favorável às mulheres, no entanto, um dos modelos não apresentou significância estatística, de forma que os resultados podem ter sido afetados pela baixa representatividade das ocupações artístico-culturais no mercado de trabalho brasileiro. Além disso, confirmou-se que, para o ano de 2018, houve discriminação de rendimentos contra as mulheres do setor, apesar de a maior parte do diferencial ser atribuída às dotações dos grupos. Palavras-Chave: Trabalho Artístico-Cultural. Discriminação de Gênero. Decomposição de Oaxaca-Blinder.
AI-Driven Anomaly Detection in Network Monitoring Techniques and Tools
Authors:   USA, Aluwala Aakash
Published: June 2024

Effective network monitoring is crucial for maintaining performance and security. Traditionally, tools use threshold-based methods for anomaly detection but struggle to detect complex patterns in modern dynamic networks. This paper investigates leveraging machine learning to augment monitoring capabilities. Key network monitoring tools are described along with how they currently handle anomaly detection. Machine learning techniques for developing predictive models from historical data are then discussed. A framework for integrating trained models as add-ons to existing tools is proposed. These AI-driven approaches are shown to provide more accurate and automated anomaly detection compared to legacy techniques.