bluuebunny/crossref_metadata_2025 huggingface dataset:
Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease
Authors: Imai Yuzuru , Inoshita Tsuyoshi , Meng Hongrui , Shiba-Fukushima Kahori , Hara Kiyotaka Y. , Sawamura Naoya , Hattori Nobutaka
Published: November 2019

Mitochondrial degeneration is considered one of the major causes of Parkinson’s disease (PD). Improved mitochondrial functions are expected to be a promising therapeutic strategy for PD. In this study, we introduced a light-driven proton transporter, Delta-rhodopsin (dR), to Drosophila mitochondria, where the mitochondrial proton-motive force (Δp) and mitochondrial membrane potential are maintained in a light-dependent manner. The loss of the PD-associated mitochondrial gene CHCHD2 resulted in reduced ATP production, enhanced mitochondrial peroxide production and lower Ca2+-buffering activity in dopaminergic (DA) terminals in flies. These cellular defects were improved by the light-dependent activation of mitochondrion-targeted dR (mito-dR). Moreover, mito-dR reversed the pathology caused by the CHCHD2 deficiency to suppress α-synuclein aggregation, DA neuronal loss, and elevated lipid peroxidation in brain tissue, improving motor behaviors. This study suggests the enhancement of Δp by mito-dR as a therapeutic mechanism that ameliorates neurodegeneration by protecting mitochondrial functions.
Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands
Authors: Belorusova Anna Y. , Evertsson Emma , Hovdal Daniel , Sandmark Jenny , Bratt Emma , Maxvall Ingela , Schulman Ira G. , Åkerblad Peter , Lindstedt Eva-Lotte
Published: November 2019

Liver X receptors (LXRs) are attractive drug targets for cardiovascular disease treatment due to their role in regulating cholesterol homeostasis and immunity. The anti-atherogenic properties of LXRs have prompted development of synthetic ligands, but these cause major adverse effects—such as increased lipogenesis—which are challenging to dissect from their beneficial activities. Here we show that LXR compounds displaying diverse functional responses in animal models induce distinct receptor conformations. Combination of hydrogen/deuterium exchange mass spectrometry and multivariate analysis allowed identification of LXR regions differentially correlating with anti-atherogenic and lipogenic activities of ligands. We show that lipogenic compounds stabilize active states of LXRα and LXRβ while the anti-atherogenic expression of the cholesterol transporter ABCA1 is associated with the ligand-induced stabilization of LXRα helix 3. Our data indicates that avoiding ligand interaction with the activation helix 12 while engaging helix 3 may provide directions for development of ligands with improved therapeutic profiles.
Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction
Authors: Thomas Adam , Cutlan Rhys , Finnigan William , van der Giezen Mark , Harmer Nicholas
Published: November 2019

Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their properties, especially their poor stability, render them sub-optimal for use in a bioindustrial pipeline. Here, we employed ancestral sequence reconstruction (ASR) – a burgeoning engineering tool that can identify stabilizing but enzymatically neutral mutations throughout a protein. We used a three-algorithm approach to reconstruct functional ancestors of the Mycobacterial and Nocardial CAR1 orthologues. Ancestral CARs (AncCARs) were confirmed to be CAR enzymes with a preference for aromatic carboxylic acids. Ancestors also showed varied tolerances to solvents, pH and in vivo-like salt concentrations. Compared to well-studied extant CARs, AncCARs had a Tm up to 35 °C higher, with half-lives up to nine times longer than the greatest previously observed. Using ancestral reconstruction we have expanded the existing CAR toolbox with three new thermostable CAR enzymes, providing access to the high temperature biosynthesis of aldehydes to drive new applications in biocatalysis.
Microbial biofilm formation and degradation of octocrylene, a UV absorber found in sunscreen
Authors: Suleiman Marcel , Schröder Carola , Kuhn Michael , Simon Andrea , Stahl Alina , Frerichs Heike , Antranikian Garabed
Published: November 2019

Octocrylene is a widely used synthetic UV absorber of sunscreens and found in several environments. Ecological consequences of the accumulation of UV filters are widely discussed. This is the first report revealing the microbial potential to transform octocrylene. A microbial community comprising four bacterial species was enriched from a landfill site using octocrylene as carbon source. From these microorganisms Mycobacterium agri and Gordonia cholesterolivorans were identified as most potent applying a new “reverse discovery” approach. This relies on the possibility that efficient strains that are already isolated and deposited can be identified through enrichment cultures. These strains formed massive biofilms on the octocrylene droplets. GC-MS analysis after cultivation for 10 days with M. agri revealed a decrease in octocrylene concentration of 19.1%. LC-MS/MS analysis was utilized in the detection and quantification of transformation products of octocrylene. M. agri thus represents an ideal candidate for bioremediation studies with octocrylene and related compounds.
Multiple superconducting phases in a nearly ferromagnetic system
Authors: Braithwaite D. , Vališka M. , Knebel G. , Lapertot G. , Brison J.-P. , Pourret A. , Zhitomirsky M. E. , Flouquet J. , Honda F. , Aoki D.
Published: November 2019

The nearly ferromagnetic superconductor UTe2 shows several intriguing phenomena, including an extraordinary reinforcement of superconductivity in very strong magnetic fields. Here we show that pressure tunes the system to a more correlated state and probable magnetic order. The superconducting critical temperature is also strongly enhanced, reaching almost 3 K, a new record for U-based heavy fermion superconductors. Most spectacularly under pressure we find a transition within the superconducting state, putting UTe2 among the very rare systems having multiple superconducting phases. UTe2 under pressure is a treasure trove of several of the most fascinating phenomena in unconventional superconductivity and may well be a keystone in their understanding.
Catalytic mechanisms of oxygen-containing groups over vanadium active sites in an Al-MCM-41 framework for production of 2,5-diformylfuran from 5-hydroxymethylfurfural
Authors: Liu Li-Juan , Wang Zhao-Meng , Lyu Ya-Jing , Zhang Jin-Feng , Huang Zhou , Qi Ting , Si Zhen-Bing , Yang Hua-Qing , Hu Chang-Wei
Published: November 2019

In the V-doped Al-MCM-41 framework, the [V-1] active site with a hydroxyl group displays better catalytic activity than the [V-0] active site without a hydroxyl group toward the oxidation of 5-hydroxymethylfurfural to 2,5-diformylfuran.
A photopolymerizable thermoplastic with tunable mechanical performance
Authors: Alim Marvin D. , Childress Kimberly K. , Baugh Neil J. , Martinez Alina M. , Davenport Amelia , Fairbanks Benjamin D. , McBride Matthew K. , Worrell Brady T. , Stansbury Jeffrey W. , McLeod Robert R. , Bowman Christopher N.
Published: November 2019

Semicrystalline polymeric materials possessing extraordinary mechanical properties were rapidly fabricated using light from low viscosity liquids at room temperature.
Comprehensive analysis of the lncRNA-associated ceRNA network identifies neuroinflammation biomarkers for Alzheimer's disease
Authors: Zhou Yuanshuai , Xu Zhongjuan , Yu Yanzhen , Cao Junjun , Qiao Yong , Qiao Hong , Suo Guangli
Published: November 2019

Accumulating evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in Alzheimer's disease (AD).
X-ray fluorescence spectroscopy (XRF) applied to plant science: challenges towards in vivo analysis of plants
Authors: Montanha Gabriel Sgarbiero , Rodrigues Eduardo Santos , Marques João Paulo Rodrigues , de Almeida Eduardo , dos Reis André Rodrigues , Pereira de Carvalho Hudson Wallace
Published: November 2019

X-ray fluorescence spectroscopy (XRF) is an analytical tool used to determine the elemental composition in a myriad of sample matrices. Due to the XRF non-destructive feature, this technique may allow time-resolved plant tissue analyses under in vivo conditions, and additionally, the combination with other non-destructive techniques. In this study, we employed handheld and benchtop XRF to evaluate the elemental distribution changes in living plant tissues exposed to X-rays, as well as real-time uptake kinetics of Zn(aq) and Mn(aq) in soybean (Glycine max (L.) Merrill) stem and leaves, for 48 hours, combined with transpiration rate assessment on leaves by an infrared gas analyzer (IRGA). We found higher Zn content than Mn in stems. The latter micronutrient, in turn, presented higher concentration in leaf veins. Besides, both micronutrients were more concentrated in the first trifolium (i.e., youngest leaf) of soybean plants. Moreover, the transpiration rate was more influenced by circadian cycles than Zn and Mn uptake. Thus, XRF represents a convenient tool for in vivo nutritional studies in plants, and it can be coupled successfully to other analytical techniques.
Preparation and evaluation of a hierarchical Bi2MoO6/MSB composite for visible-light-driven photocatalytic performance
Authors: Cai Lu , Zhou Yarui , Wang Zhen , Chen Jinlong , Ji Lili , Guo Jian , Wang Yaning , Song Wendong , Liu Jianshe
Published: November 2019

In this study, waste mussel shells were used to remove dyes in aqueous solution.
An insight into biomimetic 4D printing
Authors: Kanu Nand Jee , Gupta Eva , Vates Umesh Kumar , Singh Gyanendra Kumar
Published: November 2019

4D printed objects are indexed under additive manufacturing (AM) objects.
Flexible on-demand cell-free protein synthesis platform based on a tube-in-tube reactor
Authors: Zhou Caijin , Lin Xiaomei , Lu Yuan , Zhang Jisong
Published: November 2019

A flexible on-demand cell-free protein synthesis platform using a tube-in-tube reactor is established for continuous synthesis of different protein drugs.
Constructing 2D MOFs from 2D LDHs: a highly efficient and durable electrocatalyst for water oxidation
Authors: Cai Mengke , Liu Qinglin , Xue Ziqian , Li Yinle , Fan Yanan , Huang Aiping , Li Man-Rong , Croft Mark , Tyson Trevor A. , Ke Zhuofeng , Li Guangqin
Published: November 2019

We demonstrate a facile ligand-assisted synthetic method, promoting the transformation of 2D layered double hydroxides (LDHs) into 2D metal–organic frameworks (MOFs) with a superior water oxidation reaction performance and durable stability.
High temperature lead-free BNT-based ceramics with stable energy storage and dielectric properties
Authors: Zhu Chaoqiong , Cai Ziming , Luo Bingcheng , Guo Limin , Li Longtu , Wang Xiaohui
Published: November 2019

The designed 0.8BNTSZ–0.2NN ceramic demonstrates superb temperature stability with a capacitance variation <±15 from −55 °C to 545 °C.
Correction: Vessel graft fabricated by the on-site differentiation of human mesenchymal stem cells towards vascular cells on vascular extracellular matrix scaffold under mechanical stimulation in a rotary bioreactor
Authors: Li Na , Rickel Alex P. , Sanyour Hanna J. , Hong Zhongkui
Published: November 2019

Correction for ‘Vessel graft fabricated by the on-site differentiation of human mesenchymal stem cells towards vascular cells on vascular extracellular matrix scaffold under mechanical stimulation in a rotary bioreactor’ by Na Li et al., J. Mater. Chem. B, 2019, 7, 2703–2713.
Greatly enhanced discharge energy density and efficiency of novel relaxation ferroelectric BNT–BKT-based ceramics
Authors: Hu Di , Pan Zhongbin , Zhang Xiang , Ye Haoran , He Zhouyang , Wang Mingkun , Xing Shuang , Zhai Jiwei , Fu Qiang , Liu Jinjun
Published: November 2019

The 0.65(NBT-BKT)–0.35SBT ceramic possesses an ultra-high recoverable energy storage density (Wrec ∼ 4.06 J cm−3) and maintains a relatively high efficiency (η = ∼87.3%).
Brain-Derived Neurotrophic Factor Genotype–Specific Differences in Cortical Activation in Chronic Aphasia
Authors: Kristinsson Sigfus , Yourganov Grigori , Xiao Feifei , Bonilha Leonardo , Stark Brielle C. , Rorden Chris , Basilakos Alexandra , Fridriksson Julius
Published: November 2019

Purpose

The brain-derived neurotrophic factor (BDNF) gene has been shown to be important for synaptic plasticity in animal models. Human research has suggested that BDNF genotype may influence stroke recovery. Some studies have suggested a genotype-specific motor-related brain activation in stroke recovery. However, recovery from aphasia in relation to BDNF genotype and language-related brain activation has received limited attention. We aimed to explore functional brain activation by BDNF genotype in individuals with chronic aphasia. Consistent with findings in healthy individuals and individuals with poststroke motor impairment, we hypothesized that, among individuals with aphasia, the presence of the Met allele of the BDNF gene is associated with reduced functional brain activation compared to noncarriers of the Met allele.

Method

Eighty-seven individuals with chronic stroke-induced aphasia performed a naming task during functional magnetic resonance imaging scanning and submitted blood or saliva samples for BDNF genotyping. The mean number of activated voxels was compared between groups, and group-based activation maps were directly compared. Neuropsychological testing was conducted to compare language impairment between BDNF genotype groups. The Western Aphasia Battery Aphasia Quotient (
Kertesz, 2007
) was included as a covariate in all analyses.

Results

While lesion size was comparable between groups, the amount of activation, quantified as the number of activated voxels, was significantly greater in noncarriers of the Met allele (whole brain: 98,500 vs. 28,630,
p
< .001; left hemisphere only: 37,209 vs. 7,000,
p
< .001; right hemisphere only: 74,830 vs. 30,630,
p
< .001). This difference was most strongly expressed in the right hemisphere posterior temporal area, pre- and postcentral gyrus, and frontal lobe, extending into the white matter. Correspondingly, the atypical BDNF genotype group was found to have significantly less severe aphasia (Western Aphasia Battery Aphasia Quotient of 64.2 vs. 54.3,
p
= .033) and performed better on a naming task (Philadelphia Naming Test [
Roach, Schwartz, Martin, Grewal, & Brecher, 1996
] score of 74.7 vs. 52.8,
p
= .047). A region of interest analysis of intensity of activation revealed no group differences, and a direct comparison of average activation maps across groups similarly yielded null results.

Conclusion

BDNF genotype mediates cortical brain activation in individuals with chronic aphasia. Correspondingly, individuals carrying the Met allele present with more severe aphasia compared to noncarriers. These findings warrant further study into the effects of BDNF genotype in aphasia.

Supplemental Material

https://doi.org/10.23641/asha.10073147

Presentation Video

https://doi.org/10.23641/asha.10257581
Neuroplasticity in Aphasia: A Proposed Framework of Language Recovery
Authors: Kiran Swathi , Meier Erin L. , Johnson Jeffrey P.
Published: November 2019

Purpose

Despite a tremendous amount of research in this topic, the precise neural mechanisms underlying language recovery remain unclear. Much of the evidence suggests that activation of remaining left-hemisphere tissue, including perilesional areas, is linked to the best treatment outcomes, yet recruitment of the right hemisphere for various language tasks has also been linked to favorable behavioral outcomes. In this review article, we propose a framework of language recovery that incorporates a network-based view of the brain regions involved in recovery.

Method

We review evidence from the extant literature and work from our own laboratory to identify findings consistent with our proposed framework and identify gaps in our current knowledge.

Results

Expanding onHeiss and Thiel's (2006)hierarchy of language recovery, we identify 4 emerging themes: (a) Several bilateral regions constitute a network engaged in language recovery; (b) spared left-hemisphere regions are important components of the network engaged in language recovery; (c) as damage increases in the left hemisphere, activation expands to the right hemisphere and domain-general regions; and (d) patients with efficient, control-like network topology show greater improvement than patients with abnormal topology. We propose a mechanistic model of language recovery that accounts for individual differences in behavior, network topology, and treatment responsiveness.

Conclusion

Continued work in this topic will lead us to a better understanding of the mechanisms underlying language recovery, biomarkers that influence recovery, and, consequently, more personalized treatment options for individual patients.

Presentation Video

https://doi.org/10.23641/asha.10257590
The use of the SMED method in improvement of production enterprises
Authors: Stuglik Joanna , Gródek-Szostak Zofia , Kajrunajtys Danuta
Published: November 2019

The aim of the paper is to present the results of introducing the SMED method on one of the production lines in a selected production company. For the purposes of this study, a single bottling line for filling 200 ml and 250 ml glass bottles with carbonated drinks was selected. Upon analyzing the process of mixer washing in terms of time, it was shown that in individual steps, the total single washing time was 5 hours 3 minutes on average, which accounted for about 19% of the total retooling of the production line. However, after using the SMED method, this process has taken 3 hours 50 minutes. Thus, a saving of 1 hour 13 minutes was obtained after shortening the retooling, which allowed to extend the production process.
A genetic algorithm modelling of temperature distributions in the AZ31B magnesium alloys with 7075 aluminium alloy friction welded joints
Authors: Winiczenko Radosław , Sibicki Andrzej , Skoczylas Paweł , Trajer Jędrzej
Published: November 2019

This paper presents a genetic algorithm modelling of temperature distribution during heating and cooling of AZ31B magnesium alloys with 7075 aluminium alloy friction welded joints. The temperature distributions estimated in the joints using K-type thermocouples with the accuracy of ±⚟0.1°C. The thermocouples were installed in 1.2 mm holes at the periphery joint - 5, 10, and 15 mm from the weld interface. Temperature reading was performed with a digital thermometer with the requisition frequency of 1000Hz during friction welding. Maximum temperature measurements in the half-radius of the analysed joints were equal to 305°C and 324°C, for the AZ31B magnesium alloy and 7075 aluminium alloy specimens, respectively. Both temperature and increasing temperature gradient at the axial specimens were higher than those at the half-radius and periphery of the joints. The empirical models for heating T=a/b+exp(ct) and cooling phases T=a-btc were formulated by the authors of this study. These models used to describe the temperature curves of welding process. The goodness of fit of tested mathematical models to the experimental data was evaluated with the coefficient of determination R2. A nonlinear regression analysis was conducted to fit the models by genetic algorithm (GA) using computer program MATLAB.
The impact of biochar dosing with simultaneous fertilization with a biogas plant digestate on the volumetric density of soil
Authors: Sikora Jakub , Sadowska Urszula , Klimek-Kopyra Agnieszka , Gliniak Maciej
Published: November 2019

The paper analyses the impact of biochar on the volumetric density of the soil, with simultaneous fertilization with an agricultural biogas plant digestate. For the purpose of the research, 10 experimental fields were prepared for the study, in accordance with good agricultural practice. To verify the results, a single-factor variance analysis was performed, which demonstrated a significant differentiation between the dosing of the biochar and the values of the volumetric density of the soil. Using the digestate simultaneously with the biochar addition further increased the disparity in the soil’s volumetric density between the respective biochar doses.
Effect of B2O3 on the carbothermal reduction of vanadium titanium magnetite
Authors: Xiangdong Xing , Sha Wang , Zhuogang Pang , Qiuli Zhang
Published: November 2019

The effect of B2O3 on the carbothermal reduction of vanadium titanium magnetite was investigated under different temperatures by isothermal experiments. XRD analysis, SEM analysis and kinetic analysis were used to reveal the mechanism of B2O3 in the reduction process. The results showed that B2O3 could accelerate the reduction rate of vanadium titanium magnetite, and the suitable addition amount was 3%. B2O3 was easy to melt during carbothermal reduction, B3+ diffused into the crystal lattice of ferrotitanium compound, resulting in a decrease in binding energy and an increase in lattice parameters. B2O3 had also an erosion effect on the surface of the iron ore, and the contact area between reducing agent CO and vanadium titanium magnetite increased, thereby promoting the reduction. Low melting point compound CaO ∙ B2O3 formed after adding B2O3, which could improve the fluidity of the system and change the melting point of non-ferrous phase to further promote the growth and aggregation of iron particles. The reduction process was firstly limited by the first-order chemical reaction, then it was controlled by three-dimensional diffusion of reactants. The activation energy calculated by the best model was smaller than that of without adding B2O3.
Life-purpose orientations of today’s university students of a multicultural region
Authors: Cheremisova Irina , Zakharova Elena , Nikulova Ekaterina
Published: November 2019

You The article presents an empirical study of the life-purpose orientations of thirdand fourth-year students of various directions of undergraduate training: “Psychology”, “Environmental sciences”, “Economics”, “Law” of the Volga Humanitarian Institute (branch) of Volgograd State University. The study used the Life-Purpose Orientations Test (LPO technique) of D.A. Leontiev as the main technique. The results of respondents in this sample correspond to the average level of indicators on all scales. In addition, students were offered the author’s questionnaire “What is valuable to you?” An analysis of the answers led to the conclusion that spiritual values are a priority for almost all students and “Family” is the most significant value.
Sense and sense-forming technologies in teaching foreign languages
Authors: Godovanaya Olga
Published: November 2019

In the modern educational setting, there is a trend towards the transition to digital learning, but many psychologists and educators believe that this process will lead to a simple absorption of information and the degradation of education system as a whole. This article deals with the importance of bringing knowledge to the personal semantic level, it also considers the mechanisms of generating sense and highlights the techniques that facilitate the initiation of semantic value in the context of teaching foreign languages.
Pedagogical conditions for the formation of foreign-language sociocultural competence of cadets of educational organizations of the Federal Penal Service of Russia
Authors: Shilina Nina , Aksenova Galina , Ganishina Irina , Aksenova Polina
Published: November 2019

Currently it is necessary to learn cultures of other people, and it is therefore important to find new areas and forms of cultural cooperation. One way to meet these challenges is to learn foreign languages. The sociocultural component in the content of foreign language instruction plays a significant role in the development of the cadets personality, as it provides an opportunity not only to familiarize themselves with the heritage of the country’s culture of its target language country, but also to compare it with the cultural values of his country, which contributes to the formation of the common culture of a cadet. The relevance of problem of the formation of foreign-language sociocultural competence of cadets of the educational organizations of the Federal Penal Service (FPS) of Russia is defined by the social order of society which found the reflection in the Concept of Development of the Penal system of the Russian Federation till 2020 and also it is defined by the increased requirements of acquisition of a foreign language and search of the ways of the formation of foreign-language sociocultural competence promoting formation of bases intellectual, the cultural, professional and communicative developed identity of a specialist.
The possibility of new-didactics in hospital pedagogy: psycho-technical approach
Authors: Zorina Ekaterina , Gurtskoy Dmitry
Published: November 2019

The article deals with the practice of organizing the educational process of long-term ill children in a medical hospital. As of basic educational technologies applied smiltenei. The features of psychological and pedagogical support of schoolchildren are described.
Satisfaction of the international students with the content of master’s programs in the field of the management at metropolitan university
Authors: Fedotova Olga , Platonova Elena , Sorokina Galina , Tong Bu
Published: November 2019

That paper is motivated by the fact that the development of export potential of higher education is one of the most significant trends in the modern world educational space. The main form of export higher education in Russia is the training of the international students at local universities. In recent years, there has been an increase in the number of foreign citizens studying at Russian universities. However, in order to attract young people from foreign countries, it is important to identify the level of satisfaction of university students with the content of educational programmes, primarily at the master’s programs. The study shows the need to strengthen the practical orientation of programs and focus on the individual needs of certain groups of international students, taking into account their future careers and socio-cultural practices in the country in which university graduates are going to work in the position of manager.
Strategic management of an educational organization of a technical and professional orientation in the context of integration processes in the post-Soviet educational space
Authors: Khozhanova Almira , Zvezdina Galina , Elagina Marina , Zvezdina Ekaterina
Published: November 2019

The article presents the generalized experience of implementation of technology of strategic management of educational organization of technical and professional orientation in the post-Soviet space on the example of the Republic of Kazakhstan. The urgency of the studied problem in the conditions of convergence of educational policy of Russia and Kazakhstan is proved, the necessity of flexible response of educational systems of national States to the needs of the region and challenges of the modern digital economy is shown. Methodological bases of strategic management are considered, features of management of educational organizations in the conditions of transforming economy are shown. The scientific novelty of the article is the design of the development of an educational organization, improving its competitiveness with the help of strategic management technology on the example of the Municipal state-owned enterprise “College of business and service” Semey, Republic of Kazakhstan. The structure of strategic planning in the form of a technological process consisting of the implementation of interrelated actions from the moment of necessity in the development to the implementation of the strategy is presented.
Personal determinants of style features of pedagogical interaction as a factor of successful professional activity of the teacher
Authors: Ogannisyan Larisa , Kotov Sergey , Akopyan Marina , Borzilov Yury
Published: November 2019

This study focuses on the problem of relationships between personality traits and stylistic characteristics of professional interaction between a teacher and student, the consideration of personal determinant of the stylistic peculiarities of their interaction, as well as the styles of professional activity of a teacher. The model of interaction of subjects of educational process, from the point of view of innovative personality-oriented education is considered. And the result of this interaction is the transformation of educational features into personal and the transition to personal meanings. It is the personal importance of the subject of interaction and the interaction itself that contributes to the formation of the subjective position of the student and the teacher. The main emphasis is placed on the subject-subject interaction of participants of the educational process, personal determinants of style features of psychological and pedagogical interaction, which contribute to the development of the success of professional activity of the teacher.
Psychological and pedagogical follow-up of younger students with special abilities in terms of global education
Authors: Sirotkin Oleg , Fetalieva Laura , Chumicheva Raisa , Ali Ali Hiwa Khafar
Published: November 2019

The main approaches to the model designing of psychological and pedagogical follow-up of students in the context of contemporary global challenges are disclosed in the article; the designing principles, the structure of the model of psychological and pedagogical follow-up of students with special educational opportunities are also described in the article; it also presents humanitarian technology of psychological and pedagogical guiding and support for students with special educational capabilities, changing the position of the teacher in educational and extracurricular activities.
Taking account of test takers’ personal characteristics in language test development process
Authors: Baluyan Svetlana
Published: November 2019

The article presents the results of a study aimed at solving the problem of improving the quality of a language test. It was found that taking into account test takers’ individual characteristics that may affect their test performance, namely their personal characteristics, general and specific knowledge, language ability level and the emotional component at the design stage allows to increase reliability, interactiveness, impact, authenticity and even practicality of the test, which, in turn, contribute in its overall effectiveness.
Professional development of education managers in modern reality: psychological resources and risks
Authors: Shcherbakova Tatyana , Misirov Dinamutdin , Kirik Vladimir , Loseva Irina
Published: November 2019

The article shows the importance of human capital development in the field of management for the effective solution of the problems of modernization of modern education. This article is aimed at identifying specific resources and risks that are reflected in the process of professional development of the Manager today. For the successful activity of the Manager in the field of education, it is important to update his motivation for growth and competence, complex reflection of clusters of individual risks and resources, focus on continuous self-development. The article studies and describes the content characteristics of managers ’ ideas about psychological factors that can facilitate or block professional and personal growth. The attention is focused on the role of the education Manager in ensuring effective activity, the level of subjective control, which reflects the degree of internality, autonomy and responsibility for management decisions and the nature of professional activity. It is emphasized that the role of subjective control of the Manager increases in the context of risks of modernization of the modern educational system. Levels of acceptance of information on own resources and risks as bases of modeling of further development are revealed.
Social and political activity of youth: the content and social and psychological characteristics
Authors: Klenova Milena
Published: November 2019

The purpose of the study presented in this article is to study the social and psychological characteristics of activity of modern youth in the context of its social and political activity. The relevance of the study carried out involves on the basis of theoretical data the necessity to create practice-oriented recommendations aimed at development of social and political activity of youth, taking into account the social demand. An empirical study involved 150 people (at the age of 18 to 27 y. o.). The social and psychological study devoted to the study of social and psychological characteristics of social and political activity, helped to establish a number of features that make up the psychological content of this phenomenon. In that way, social and political activity is heavily tied to civic and protest activity, which is confirmed by the obtained correlation relationships. The factor analysis carried out revealed 3 main factors, differentiated by the presence or absence of a load in relation to social and political activity, which we called: “Citizens”, “Oppositionists”, “Indifferents”, that reflect the psychological content of social activity.
Structural organization of emotional burnout in call-center operators with different communicative tolerance
Authors: Suroedova Elena , Li Tianqi
Published: November 2019

The author considers the problem of the state of the structure of emotional burnout in labor subjects with different levels of communicative tolerance. The study found that call center operators with an average level of tolerance are more pronounced manifestation of emotional burnout. The phases of emotional burnout are a basic component in the structure of emotional burnout.
The structural organization of the manifestations of professional personality deformation in teachers with different levels of situational reflection
Authors: Uvarova Galina , Shevkieva Nogala
Published: November 2019

The study of the structural organization of the manifestations of the professional deformation of the personality of teachers with low and high level of situational reflection. Using structural psychological analysis, it was established that the structure of the manifestations of professional deformation of the personality of teachers with a low level of situational reflection is characterized by a low degree of integration of its components. For teachers with a high level of situational reflection, on the contrary, the structure of the manifestations of professional personality deformation is more consistent, the basic components that ensure the structural integration of the system conservatism, dogmatism.
The study of the responsibility of persons who don’t have children as a promising area of psychological and pedagogical support of future parents
Authors: Gremyachih Marina
Published: November 2019

The article describes the problem of psychological support and training for such an untraditional category of people for a customized education system as people expecting or planning to have a child. The results of the study of responsibility as a personal property in the context of parent-child relationships are presented; in particular, the level of severity of the responsibility variables determined using the “Test of liability judgments” by A.I. Krupnova. The primary data underwent mathematical processing, which made it possible to determine the normality of the distribution of the sample, and subsequently establish statistically significant differences between harmonic and inharmonic responsibility variables. By mathematical processing of the data, the severity levels of the variables of the target, motivational, cognitive, productive, dynamic, emotional, regulatory and evaluative-reflexive components of responsibility are determined and the percentage of persons from the surveyed sample who have high, above average, average, below average and low levels is revealed parameters. Interpretation of the data obtained during the study, their analysis allow us to determine the features of the structure of responsibility of people who are expecting or planning to have a baby, as well as draw conclusions about the features of its development.
Emotional intelligence, social emotions, parental involvement in the emotional life of senior preschoolers: development and interrelation
Authors: Lebedenko Olga
Published: November 2019

The article analyzes the category of emotional intelligence and gives grounds for its significance in the social situation of the development of preschoolers. Various approaches to the analysis of the issue of emotional intelligence of a person are presented, the characteristics of its formation in preschool age are shown. Partial programs on the development of the emotional sphere and emotional intelligence of preschoolers are briefly reviewed. Empirically it has been proved that there is an interrelation between the degree of differentiation of social emotions of children with the level of emotional intelligence of preschoolers, as well as an interrelation between the indicators of emotional intelligence of senior preschoolers and the degree of parental involvement in the emotional life of their children. The necessity of organizing work on the development of emotional intelligence of senior preschoolers is substantiated, provided that the children’s parents are included as participants of educational relations.
Psychological features of communicative personality behavior in the Internet space
Authors: Luchinkina Irina , Guanxu Wen
Published: November 2019

The article determines that belonging to one type or another of a person’s communicative behavior in the Internet space is determined by a specific ratio of psychological factors namely: a combination of cognitive, motivational, affective components of a person’s communicative behavior in the Internet space and the level of constructive-destructive behavior. The author proposes a typology of communicative behavior of a person depending on the type of cognitive distortion: destructive types of communicative behavior of a person in the Internet are based on cognitive distortions such as depreciation of the positive, mental filter, overgeneralization, dichotomous thinking, and catastrophization. The psychological characteristics of users conducting provocative activities on the network are investigated; prone to provocative online activities; ascribing to themselves the conduct of provocative activities in the network; not leading provocative online activities.
Gender transit as a factor of anxiety of personality of female students
Authors: Rjabikina Zinaida , Hozjainova Tatyana , Hozjainova Polina , Prisjagin Pavel
Published: November 2019

Problems regarding the transformation of gender identification of female students are analyzed in the article. Under consideration are the results of researches, testifying the reduction of femininity of females and increasing of masculinity. The conclusion on relation of gender characteristics (femininity masculinity) with such integral indicator of state of personality as anxiety has been statistically confirmed. It has been determined, that domination of masculine characteristics of female students is accompanied with increased level of anxiety, while feminine characteristics are related to moderate anxiety. It has been concluded, that when masculinization is increased, the anxiety of females is explained by their orientation to increased level of ambitions, responsibility, social activity, which conditions more complicated existence of females.
Socio-psychological factors of students’ adherence to various forms of social activity
Authors: Shamionov Rail
Published: November 2019

Social activity is the most important sphere of students’ socialization. In the process of inclusion into various forms of social activity they learn a new experience of interaction with other people, attitudes and values that are the most important ones for their social self-realization. The purpose of the present study is to investigate social and psychological factors of students adherence to various forms of social activity. 215 students of both genders aged М=20.2; SD=2.4 (42 % male) took part in the study. In order to evaluate socio-demographic indicators, we have developed a questionnaire; to study adherence to a certain form of social activity, conditions and effects of personal socialization, as well as the acceptable role in activity, we used series of 5-point scales. The intensity / diversity of social activity is associated with socio-demographic (gender, age) and socio-psychological (socialization conditions and beliefs in the possibility of free participation in social life) factors. The degree of involvement of students in civil forms of social activity is very low; the highest degree of manifestation can be observed in leisure and Internet-network forms of social activity. The most preferred roles (voluntary and involuntary participation, organization and initiative) are associated with socialization effects.
The Development of Students’ Cross-cultural Competence in the Conditions of Transitive Society
Authors: Takhokhov Boris
Published: November 2019

The study is devoted to the substantiation of the need for the development of students’ cross-cultural competence at the time of transitive society: it demonstrates that the current stage of social development has an actualizing effect on the psychology of the individual due to the fact that the society and its individual representative resemble the image of two-faced Janus, when one side of the person is turned to the past and the other – to the future. Under these conditions cross-cultural competence as an activity-oriented concept, the aim of which is a social adaptation of the student’s personality through the acculturation in the multicultural world, becomes a psychological and pedagogical imperative. It is noted that the cross-cultural competence in the era of postmodernism and globalization contributes to the education of students in the spirit of openness, pluralism of tastes, opinions and tolerance; at the cognitive level it is a significant expansion of cognitive space, a better understanding of both personal and other cultures. The Methodological Base of the Study: the humanistic paradigm in education and social Sciences, system, activity, cultural and personality-oriented approaches. The Research Methods: analysis and synthesis, systematization and classification, observation and generalization.
Features of acceptance by teachers of values of inclusion
Authors: Yumatova Irina
Published: November 2019

This paper discusses one of the aspects of the readiness of teachers to work with children having problems of development in the conditions of transitive society in Russia. The analysis of the main characteristics of the transitive society is carried out, the authors identify those that are associated with changes in the value system of teachers, including those who work with special children The results of empirical research of teachers ’ readiness to work with children with developmental problems depending on their values of inclusion are presented.
Study of the correlation of factors affecting frequency of social activity transfer from virtual environment to real-world environment and vice versa
Authors: Zagranichniy Anton
Published: November 2019

The article presents research results demonstrating interrelation between factors affecting frequency of social activity transfer from the virtual environment to the real-world one and vice versa. In the course of the study we investigated 19 different factors, including socio-demographic characteristics, amount and specificity of contacts in each of the environments, subjective assessment of social activity characteristics in various environments. The study involved 214 respondents aged 15 to 24 from the cities of Balakovo, Saratov, and Moscow. We analysed and interpreted the correlation interrelation via social activity transfer from one environment to another and by such factors as: place of residence size; number of friends in the virtual environment; factor regarding frequency of misconduct situations that were followed by moral responsibility in the real environment; factor of compliance with social norms in the virtual environment.
Psychological support for professional development of people with disabilities and special needs: An overview
Authors: Chernaya Anna , Obukhova Yulia
Published: November 2019

The paper addresses some core problems pertaining to psychological support for professional development of disabled people and individuals with special needs as well as means of their resolution in Russia and abroad. Underscored is the need for relevant prophylactic, correctional and educational programs designed to: (1) provide assessment of adequacy of occupational choice; (2) promote effective professional education, training, and career building; (3) implement monitoring of professional adaptation and development of people with disabilities and special needs as the primary target population.
Recent trends in the development of lifelong inclusive education of persons with disabilities in the Russian Federation
Authors: Prikhodko Oksana , Manuylova Victoria , Huseynova Ascha , Yugova Olesya
Published: November 2019

The article is devoted to the organization and implementation of lifelong inclusive education for children with special healthcare needs and disabilities at various age stages; reveals key aspects of the implementation of inclusive education in the early, preschool and adolescence stages, as well as at the stage of professional education. It describes the special conditions for access to a high-quality education of children with special educational and reveals some problems of inclusive education. Significant attention is given to the issues of tolerance within the context of inclusive education for persons with special healthcare needs and disabilities.
Socio-psychological barriers in higher inclusive education
Authors: Skuratovskaya Marina , Volodina Inna , Kobrina Larisa , Manohina Nadezhda
Published: November 2019

Higher education is one of the conditions of independent life for disabled people, a condition of their social and labor rehabilitation. Health problems are not the only serious obstacles to vocational education. No less important are the barriers in the educational environment of the University and barriers in relationships with others. It is noted that most of the difficulties in the learning process of students with disabilities are associated with their psychological characteristics - the presence of negative experiences and attitudes, the level of self-esteem, the features of life orientations. Depending on the severity of psychological characteristics, different variants of the relationship of students with disabilities with other students are possible: from full integration to disintegration and opposition behavior. It was suggested that the nature of the relationship and especially value-semantic readiness for vocational education in higher inclusive education can largely determine the prospects of personal and professional development of students with disabilities. An empirical study of peculiarities of value orientations of students with disabilities (N = 50) and students without disabilities (N = 50) was conducted using the technique of G. N. Kuznetsova on the General self-identity, self-esteem scale of Rosenberg and test of life-meaningful orientations D. A. Leontiev.