bluuebunny/crossref_metadata_2025 huggingface dataset:
Cluster Information Disclosure in Strategic Planning of Region’s Economy
Authors: Vorobev Aleksandr
Published: March 2020

The article represents the results of the analysis of existing approaches to describing economic clusters. These approaches use self-dependent characteristics that complicate evaluating and comparing clusters. Consequently, the author offers the concept of information disclosure of a cluster and its overall indicator. This indicator enables to evaluate clusters, to define a stage of their functioning and to compare results of their activity with other clusters. The existing Russian methods of describing clusters form the basis for this article. These methods are proposed by the Cluster observatory of Higher School of Economics and the Geographic information system “Industrial Parks, Science and Technology Parks and Clusters” of the Russian Federation. The author singles out three aspects of characteristics: attributive, quantitative, qualitative. The characteristics used for calculating the overall indicator of disclosure are quantitative and qualitative. They are generalized and unified using indicators of the project of the Ministry of Economic Development of the Russian Federation “Development of the Innovation Clusters – Leaders of World-Class Investment Attractiveness”. The author offers two approaches to using the information disclosure indicator: dynamic and reference. The dynamic approach enables to define a stage of cluster development using the relation of the current condition to the previous one. The reference approach defines cluster development in relation to a standard that describes its global competitiveness. Both offered approaches can be used by regional and federal government bodies as well as cluster management for taking strategic decisions on the region development.
Development Trends of the Fintech Ecosystem in Russian Economy
Authors: Sviridov Oleg , Nekrasova Inna
Published: March 2020

In modern conditions of Russian economy, to create an innovative product (or service) that meets the requirements of users it is necessary to combine resources and competencies of several companies. Issues related to the network integration of companies based on the creation of ecosystems are quite controversial. In modern scientific literature there is no consensus on the definitions of an ecosystem and the ecosystem of the financial technology market (fintech market). This substantiates the relevance of the study. In the context of the dynamic development of financial technologies in Russia, new forms of organizing the interaction of enterprises for the integration of innovative ideas, the development and creation of innovative goods and services are of particular importance. The goal of this article is to determine the essence, features and prospects of developing the fintech ecosystem of Russia. The article provides an overview of the main works devoted to substantiating the concept of an ecosystem, analyzes the features and advantages of this form of organizing the financial technology market. The authors clarify the definition “financial technology market ecosystem”, develop the classification of fintech ecosystems, and formulate the main directions of state regulation of the fintech market ecosystem. The article presents an analysis of priority initiatives aimed at the development of the Russian fintech ecosystem of the global and Russian markets of innovative financial technologies and services determined from the results of the study.
Models of Financial Behavior of the Population in the Conditions of Nanoeconomics (Tax Aspect)
Authors: Gorshkova Natalia , Ksenda Victoria
Published: March 2020

Modern economic science is developing dynamically under the influence of various factors. One of the new and relevant areas of economic research is nanoeconomics. Despite the relative novelty of this area of economic research, the foundations of theory and methodology have already been laid by a number of scientists. Nanoeconomics is defined as the individual’s economy and allows us to consider the determinants of its development, including the behavioral aspects of the individual directly affecting his economic activity. In the framework of this approach, the study of the individual’s financial behavior which directly affects the development of the financial system and the increase of country’s competitiveness becomes particularly relevant. The application of the institutional approach allows expanding the classification of financial behavior strategies adding a new type of tax behavior, which is defined as the individual behavior (incentive, protest, adaptive) associated with the obligation to pay taxes and fees, as well as the right to use tax deductions (property, social, investment). The analysis of the market of financial services, performance indicators of financial institutions, as well as tax payments and deductions shows that citizens think about their financial well-being and depending on various factors (psychological, sociological, economic, political) their financial behavior changes, which is confirmed by the analysis of statistical indicators.
Comparative Characteristics of Economy’s Social Attributes of the System Levels of Hierarchy from the Standpoint of Economic and Mathematical Modeling
Authors: Kussy Mikhail , Korolyov Oleg
Published: March 2020

As a result of the research, the paper shows the essential need to take into account the social attributes of processes and phenomena in economy. From the standpoint of the interdisciplinary approach at various levels of the system three-hierarchy (micro-meso-macro) in economy, the following characteristics of social attributes are considered: “economic agent”, “expectations of the economic agent” and “preferences of the economic agent” taking into account their heteromorphism and heterogeneity, “intersubjective relations in economy”, “trust” between economic agents, “institutions”. The conclusions made as a result of the study make it possible to formulate the concept of selecting tools for economic and mathematical modeling of processes and phenomena at various levels of the system three-hierarchy (micro-meso-macro) in economy. Further studies will make it possible to select the most relevant tools for each level of the system three-hierarchy from the numerous apparatus used to model processes and phenomena in economy taking into account the concept proposed in this paper.
Research of the Market of Land Property Rights in the Aspect of the Institutional Theory
Authors: Fedyunina Elena , Oganesyan Liliya
Published: March 2020

The article reveals the essence, the structure of the market of land property rights presented as a single system of socio-economic sanctioned rules of behavior of economic entities and contractual relations on transaction, specification and implementation of alternative methods of full or limited land property rights in short and long time periods. In the process of the research the authors reveal the features of functioning of the market of full and limited land property rights, specify the subject and object of the research, the character of exchange, the mechanism of implementing market and institutional transaction. Based on conceptual approaches of leading experts, both Western and Russian-built ones, the authors propose an algorithm of the market analysis, justify the dual market model of full and limited property rights on agricultural land, present more models of supply and demand of full rights of land ownership and market of management rights, prove leadership and institutional factors in the structure of non-price determinants of supply and demand. On the one hand, institutional factors influence the creation of a limited framework of behavior of market participants in the process of interaction, and on the other hand, set the structure of incentives for land owners in short and long term. The theoretical model was tested in the course of the empirical research in the framework of the scientific project “Monitoring the Functioning of Local Agricultural Land Markets”, the hypothesis of domination of institutional non-price determinants in the market model was confirmed and the need for market institutionalization was justified.
Dynamic Analysis of the Standard of Living and the Quality of Life of the Regional Population Using the Example of Federal Districts
Authors: Berezovskaya Elena , Kryukov Sergey
Published: March 2020

To assess the consequences of the socio-economic policy implemented in the region, it is necessary to be able to evaluate the standard of living and the quality of life of the population not only in statics, but also in dynamics. At some point, the region may not be in the best situation in terms of the standard of living and the quality of life of the population, but if it demonstrates “movement” in the right direction for several years, it can be the basis for a positive assessment of the socio-economic policy implemented in the region. The authors have developed an approach to the dynamic analysis of the trajectory of “movement” of a region in the two-dimensional space “standard of living – quality of life”. The researchers propose to use the minimum number of special selected indicators to improve the objectivity of assessing the standard of living and the quality of life of the regional population. To assess the standard of living of the regional population, the indicator “average per capita income of the population” is selected, and to assess the quality of life of the population, the indicator “life expectancy at birth” is selected. The authors propose to use not absolute values of indicators, but their ratio to the average Russian value of the same indicator in a given year in order to provide a common base for comparing regions on indicators that reflect the standard of living and the quality of life of the regional population for several years. We can judge the success of the socio-economic policy in the region during the analyzed period according to the trajectory of the region’s movement in the space “standard of living – quality of life”. The authors present the results of testing the proposed approach on the example of analyzing trajectories of “movement” of the Federal districts of the Russian Federation in the space “standard of living – quality of life” for the period 2005–2017.
Geographical Factor in Regional Development
Authors: Moroshkina Marina
Published: March 2020

Regional development of Russian regions is characterized by a high level of heterogeneity. Researchers highlight a significant number of factors affecting the level of regional development. Geographical factor is recognized as one of the most important factors. The development of border regions is similar to that of Russian regions. The purpose of the research is to determine the differentiation of border regions and to study the dynamics of its change. The object of the research is border regions united in the system. The process of unification of regions is based on geographical location. The subject of the study is the process of regional differentiation. Methods of assessing the convergence of economic entities are the instrument of researching regional differentiation of border regions. The convergence theorem analyzes the interregional differentiation of border regions and considers the possibility of their convergence. As a result of using convergence approaches based on the definition of convergent processes, the coefficient of variation is calculated. On the basis of the calculated values of the coefficient and its change, the possibility of convergence of border regions is assessed and the process of change of interregional differentiation is analyzed. Another direction, on the basis of which the analysis of regional heterogeneity of border regions is based, is the determination of the differentiation coefficient, which allows to determine the level of the gap between polar groups of regions. The goal set in the study will allow assessing the impact of geographical location on economic development and formulating directions of economic policy. Spatial heterogeneity of border regions defined by means of mathematical tools can be used when writing the Program and the Strategy for Regional Development, within which one of the competitive advantages will be the location of the territory.
Developing the Team While Travelling: Infusing Elements of High Impact Practices into a Study Abroad Course for Student-Athletes
Authors: Leupold Christopher R , Weaver Anthony G , Hall Eric H
Published: March 2020

Undergraduate institutions today are increasingly looking to adopt high impact practices (HIP) as a means to provide optimal learning experiences for their students. Study abroad courses are a particularly popular HIP offerings for students, as they provide opportunities to not only experience new cultures around the world but also to gain insights into their own cultural identities. However, because of the many demands placed on Division I collegiate student-athletes, they unfortunately are often not able to engage in such a global experience. This case study describes a credit-bearing, short-term study abroad course that not only taught Division I volleyball student-athletes about theories of culture and how to analyze culture at the individual, team, and national levels; but infused a variety of experiential activities and other elements characteristic of effective HIPs. As a means to make the course more personally relevant and meaningful to these students, special attention was given to present topics in a context specific to a collegiate athletic team. These student-athletes were introduced to a host of relevant validated models and theories of culture, and engaged in a number of individual assessments to gain insights into their cultural identities and their influences, as well as in formal assessments of as their team’s dynamics and overall effectiveness. In addition, the course included team-based activities and workshops that addressed the team’s weakest areas related to performance. identified areas in need of improvement. All of these activities were  aligned with a 10-day travel experience to Italy. Overall, this case study is an example of how an innovative course can be created to not only provide a study abroad opportunity for student-athletes, but also be tailored to address individual players’ and team needs and create a positive and lasing experience for all involved.
The doctrine of love and the stage of the divine cognition, according to the community of the third order of St. Francis of Foligno, at the turn of XIII-XIV centuries
Authors: Rodionova Yulia V.
Published: March 2020

The article presents an analysis of one of the parts of the book of Revelations of blessed Angela of Foligno, which contains the Instructiones (message) to members of the community of the third order of St. Francis. The doctrine proposes to consider the relationship with God as an object/subject of love, to which feelings and emotions are directed. The “presence of the divine Beloved” is “cognition” and can respond by generating sensations of its material presence. The author of the doctrine has practical recommendations (stages of knowledge): how to achieve junction with the divine, what steps should be taken to change the way of life. It is concluded that there was a developed teaching among the members of the community, and its medical aspect is considered.
Liturgical wooden carved cross from the collection of the Russian Icon Museum
Authors: Guvakova Elena V.
Published: March 2020

The paper considers a carved priestly cross of the XIX century from the representative collection of Ethiopian art of the Russian Icon Museum. This is one of the typical Ethiopian crosses with a characteristic rhomboid shape, with the image on the front side of the liturgical procession and the icon of the Mother of God, and ornamented on the back with a braided pattern with cross-shaped ornaments woven into it. The image of the dancing participants of the liturgical procession with drums and sistra represents a unique fusion of different traditions, the influence of the Old Testament tradition was manifested in the symbolic image of tabot.
Acianthera lueri, a New Orchid Species from the Peruvian Amazon Region
Authors: Kolanowska Marta , Szlachetko Dariusz L.
Published: March 2020

Abstract—A new species of Acianthera, A. lueri, is described and illustrated based on material collected in the Amazon region of Peru. The combination of the glabrous ovary, 3-lobed lip, and long-tailed petals distinguish A. lueri
from similar A. lanceana. The new taxon is placed within the key to identification of species reported from the Peruvian Amazon region.
Materials to the Taxonomic Revision of the Genus Epistephium (Orchidaceae, Vanilloideae) in Colombia
Authors: Szlachetko Dariusz L. , Kolanowska Marta , Baranow Przemysław
Published: March 2020

Abstract—A synoptic revision of the genus Epistephium in Colombia based on morphological evidence is presented for the first time. A total of 19 species gathered in 3 morphological groups are currently recognized in the country, including two new records: E.
ellipticum and E. sclerophyllum. Morphological characteristics of all the species are presented and illustrated by line drawings of their perianth segments, except E. lamprophyllum. An original key to the identification of Epistephium species reported in Colombia is
provided along with information on their ecology, habitat, and geographical range. Epistephium amplexicaule is lectotypified based on Article 9.3 of the International Code of Nomenclature for algae, fungi, and plants as this name was published without a holotype.
A New Species and a New Record of Ficus sect. Pharmacosycea (Moraceae) from Peru
Authors: Rivera Nicole Mitidieri , Pederneiras Leandro Cardoso , Parizaca Alexander Damián , Castillo Joaquina Albán
Published: March 2020

Abstract—Ficus sirensis is described from Ucayali, northern Peru, and a new country record for F. macrosyce Pittier is given. Diagnostic features of both species are illustrated and a taxonomic key of Ficus sect. Pharmacosycea subsect.
Petenenses from Peru is presented.
Discovery of Three New Species of Acalypha L. (Euphorbiaceae, Acalyphoideae) from Madagascar and Their Conservation Status
Authors: Montero-Muñoz Iris , Cardiel José María , Levin Geoffrey A.
Published: March 2020

Abstract—Three remarkable new species of Acalypha (Euphorbiaceae, Acalyphoideae) from Madagascar are described and illustrated. Acalypha isaloensis, found in the Isalo Massif of southwestern Ihorombe region, is morphologically similar to A. gracilipes,
but differs by its habit, indument, presence of domatia, and inflorescence sexuality. This is the first report of pocket-shaped domatia in the genus. Acalypha rabesahalana and A. tremula, found in Diana and Sava regions in the far north of Madagascar, superficially
resemble A. menavody, but they do not strongly resemble any other species known from Madagascar nor from mainland Africa. Preliminary conservation assessments of the three new species are provided, and all are considered endangered or critically endangered, despite occurring in legally
protected areas.
African American Scholars and the Margins of DH
Authors: Rambsy II Howard
Published: March 2020

Let's Cut to the Chase: African American Scholars Occupy the Margins of this Expansive Realm Known as Digital Humanities. Do well-intentioned people want more diversity in DH? Sure, they do. Do black folks participate in DH? Of course, we do. But we've witnessed far too many DH panels with no African American participants or with only one. We've paid close attention to where the major funding for DH goes. Or, we've carefully taken note of who the authors of DH-related articles, books, and bibliographies are. We've studied these things closely enough to realize who resides in prime DH real estate and who doesn't. We could speak defiantly about our marginal status the way Toni Morrison once did when she quipped, “I'm gonna stay out here on the margin, and let the center look for me” (87). Yaasss!

At the same time, though, it's worth thinking about some of the reasons why African American scholars dwell on the margins of the DH field. The processes by which we pursue graduate study and become participants in the field of African American literary studies account for why we are slow or reluctant to embrace DH. There's also the matter of segregation—our persistent exclusion from projects and opportunities that are ostensibly open to all but invariably involve primarily white scholars. Immersion in the field of African American literary studies and conversations with senior and emergent scholars reveal some of the reasons why we stand so far from the center of the DH community.
The Experimental Turn
Authors: Coles Katharine
Published: March 2020

From 2012 to 2017, I Collaborated with the Visualization Scientists Miriah Meyer and Nina Mccurdy and the Poet Julie Gonnering Lein to develop Poemage, a computational tool that identifies and visualizes complex sonic relationships in poems. The scientists sought problems that would allow them to develop breakthrough computational strategies, frameworks, or paradigms. Lein and I, the poets, realizing that much digital humanities research at the time was driven by technology and the desire to extract data from texts, remained committed to engaging the qualitative, aesthetic, close-reading experience that is central to our work.
Common and Idiosyncratic Inflation
Authors: Luciani Matteo
Published: March 2020

We use a dynamic factor model to disentangle changes in prices due to economy-wide (common) shocks, from changes in prices due to idiosyncratic shocks. Using 146 disaggregated individual price series from the U.S. PCE price index, we find that most of the fluctuations in core PCE prices observed since 2010 have been idiosyncratic in nature. Moreover, we find that common core inflation responds to economic slack, while the idiosyncratic component does not. That said, even after filtering out idiosyncratic factors, the estimated Phillips curve is extremely flat post-1995. Therefore, our results suggest that the flattening of the Phillips curve is the result of macroeconomic forces.
Model to Assess Effectiveness of Regional Mass Media
Authors: Makarenko Tamara , Kovalchuk Lyudmila
Published: March 2020

The article presents the structure of the media in the Trans-Baikal Territory. The elements of the media system include leading information agencies, television channels, periodicals, determined by the media rating in the Trans-Baikal Territory. The mass media presented in the model have different technical and technological properties allowing them to represent the interests of various social and age groups. Taking into account the interests of the maximum number of the media product consumers makes it possible to assess the overall level of awareness of the population about the events and facts of regional social and economic development, which, in the authors' view, should be considered an indicator of the regional media effectiveness. The significance of this indicator is determined by the participation of the media in the formation of values, political views, moral and ethical guidelines and motives of the population. In this context, an evaluation of the overall performance of the system and partial performance indicators of its elements is an important management task. At the same time, the task is complicated because of the lack of a generally accepted system of indicators for assessing the processes of creating and transmitting information, as well as tools for their convolution. In accordance with the purpose of the study, the authors proposed a system of indicators for assessing the factors that determine the effectiveness of the processes of creating information products at each of the media in the region, as well as indicators of the overall effectiveness of the media system of the region. Given the differences in technologies for creation and transmission of information products, the authors solved the problem of comparability of indicators and data. At the stage of obtaining integral estimates, the problem of the convolution of the obtained indicators arose. To solve the problem of convolution, the apparatus of fuzzy logic and fuzzy logic inference was used. The obtained estimates revealed a high level of awareness of the population of the Trans-Baikal Region about the events, facts and processes of regional socio-economic development. The evaluation algorithm presented in the work allows one not only to assess the overall level of effectiveness of the regional media system, but also to compare the media systems of different regions, and to monitor the activities of individual media enterprises. The principal moment of practical application of the proposed algorithm is the possibility of building on its basis a computer expert system that allows to automate the calculations and the formation of an information base.
Review: Road Transport as the Key Source of Environmental Pollution in Cities, and the Associated Human Health Risks
Authors: Николаева Ольга Вячеславовна
Published: March 2020

Road transport is a necessary attribute of urban environment. Fuel vehicles emit a great variety of pollutants, transform the environment and pose human health risks. This problem is highly recognized in the EU and US, while it is out of sufficient attention in other countries.This review article highlights road traffic as the key source of environmental pollution in cities and the associated adverse effects on human health. This problem is reviewed in details and possible solutions related traffic management, fuel quality increase and roadside territories design are described.This article is written for educational purposes to direct the attention of academia, government and businesses to road traffic as the key source of environmental pollution in the urban environment. It is especially useful for urbanists considering the negative effects of motor vehicles for human well-being in sustainable city planning.
Veridiction and Leadership in Transnational Populism: The Case of DiEM25
Authors: Fanoulis Evangelos , Guerra Simona
Published: March 2020

While research tends to explore questions of power and leadership at the national level, populism in Europe has moved beyond national borders, with an increasing number of transnational movements and organizations. This article investigates the Democracy in Europe Movement 2025 (DiEM25) and its leadership’s main speeches. Informed by both discourse theory and Michel Foucault’s work on parrhesia (veridiction), the analysis draws on readings of transnational Euroalternativism and populism, pointing out the conflicting logic of bringing them together at the transnational level. Our findings thus stress the increasing politicization of European integration as an opportunity to mobilize transnational activities, which are based on the populist ‘people vs. the elites’ dichotomy and against Brussels’ unaccountable elites (see FitzGibbon & Guerra, 2019), while indicating the limits of leadership in a populist transnational movement (de Cleen, Moffitt, Panayotu, & Stavrakakis, 2019; Marzolini & Souvlis, 2016).
EXPERIMENTAL STUDY OF TACTICAL AND TECHNICAL CHARACTERISTICS OF THE ELECTRIC DRIVE OF A STRIKEBALL WEAPON.
Authors: Berezhansky O. A. , Markov A.M.
Published: March 2020

Electro-pneumatic actuator is an accurate external modulation of combat weapons, which is used for tactical games and development of combat skills. Electro-pneumatic drive (AEG) and its advantage in high speed of fire were investigated in the experiment and the number of its shots exceeds even the number of combat weapon's shots. The other advantages are the large number of shots on a standard battery and miniature design, because weight and size are more modulation requirement than necessity.
FLOYD–WARSHALL ALGORITHM FOR SHORTEST ROUTE CALCULATION BETWEEN LATVIA'S CITIES
Authors: Gavars Raivis , Netlis-Galejs Einārs , Lazdiņš Jānis Artūrs , Kangro Ilmārs
Published: March 2020

The Floyd–Warshall algorithm is a good choice for computing paths between all pairs of vertices indense graphs, in which most or all pairs of vertices are connected by edges. For sparse graphs with non-negative edgeweights, a better choice is to use Dijkstra's algorithm from each possible starting vertex. Also, a very good thing is that thesolution is very accurate, when using a computer. In this paper, the authors tried to apply a solution using C++programming language to make possible many entries.
CALCULATION AND MODELING OF EMISSIONS FOR SOLID AND LIQUID FUELS
Authors: Spriņģe Zaiga , Laizāne Ināra
Published: March 2020

The thesis contains information on emissions and their calculations and formulas. Information about and working with ADMS Screen was reviewed. The results obtained using this program were summarized in tables and emission dispersion schedules were obtained. The information obtained was analyzed and conclusions were drawn.
POSIBILITIES OF USING DOCKER CONTAINERS
Authors: Žogots Dainis , Ežmale Sandra
Published: March 2020

Considering that in nowadays virtualization in various Information Technology (IT) systems is becoming more demanding, it is necessary to deeply understand the possibilities, advantages and risks of that kind of technologies. One of these virtualization tools is the Docker containers, which are becoming more convenient, faster, more popular and more profitable than virtual machines (VM). The aim of this work is to explore and analyze the possibilities of Docker containers and to evaluate the pros and cons of the given technology. Also determine when it is worth using Docker containers as virtualization tools for an IT system.
Residual stress in struck and cast coins
Authors: Kossolapov A J , Chugunova K S
Published: March 2020

It has been shown that the metal on struck coin surfaces demonstrates residual elastic compression while the metal on cast coin surfaces demonstrates no stress at all or, sometimes, elastic tension. Non-destructive X-ray diffraction (XRD) (the so-called 'sin 2 Ψ method') is applied
in this work for residual elastic stress analysis. It is quite an effective tool in the authentication of coins by establishing the production method of such objects (struck or cast).
Inspecting historical vaulted ceilings by means of physical and chemical analyses: an integrated approach combining active infrared thermography and reflectance spectroscopy
Authors: Sfarra S , Cheilakou E , Theodorakeas P , Ibarra-Castanedo C , Zhang H , Koui M , Maldague X
Published: March 2020

The present study discusses the experimental physicochemical results obtained from the historical vaulted ceilings of an ancient church located in central Italy. Infrared thermography (IRT) in the active configuration was used to map subsurface defects caused by a seismic event and
to discover buried structures, while the visible and near-infrared (VIS-NIR) fibre-optics diffuse reflectance spectroscopy (FORS) technique was applied to identify the pigments of wall paintings decorating the vault. Historical photographs are useful to readers in order to clarify the state
of conservation before and after the earthquake that took place in 2009. The combination of the experimental results can be useful in restoration processes.
Asma profesional: definición, tipos y etiopatogenia
Authors: Armentia Medina Alicia
Published: March 2020

Según los últimos análisis epidemiológicos, una de cada 5 personas alérgicas en los países desarrollados sufre alergia laboral. Existen más de 400 productos implicados en esta patología. Las causas y factores de riesgo son diversas y muchos pacientes afectados trabajan en la industria agroalimentaria o son profesionales sanitarios, agrícolas y de la limpieza. Los principales síntomas clínicos se puedenasociar a rinitis y dermatosis profesionales. En la mayoría de los casos de asma ocupacional, el paciente tiene que dejar su trabajo o requerir cambios sustanciales en el entorno laboral y de vida. El conocimiento profundo de las causas desencadenantes y el desarrollo de una inmunoterapiaespecíficamásprecisa, podrán mejorar a los pacientes que la sufren
Edición genética por CRISPPR-Cas y sus aplicaciones en la mejora de cultivos
Authors: Melero Royo Sergio , Martínez-García Nicole , Centeno Martín María Luz
Published: March 2020

En los últimos años se ha desarrollado una tecnología de edición genética potente, barata y relativamente sencilla de usar. Se denomina CRISPR-Cas y se basa en utilizar los componentes de un sistema de inmunidad adaptativa de bacterias para modificar el genoma de un organismo. La metodología permite realizar cortes dirigidos y específicos en la doble cadena deDNA. Gracias a la aplicación de CRISPR-Cas se han obtenido variedades de cultivo modificadas genéticamente con una eficiencia sin precedentes y que en la mayoría de los casos llegarán al mercado de una forma mucho más rápida que sus predecesores transgénicos. Entre las características incorporadas a estas nuevas variedadesse encuentran varias resistencias a estreses bióticos y abióticos, mejoras en la calidad nutricional, o incluso la capacidad para producir moléculas de interés biomédico. La legislación de estos cultivos en diferentes partes del mundo es la principal barrera a la que se enfrenta esta tecnología.
Aplicaciones del sistema CRISPR-Cas9 a la modificación genética en animales domésticos
Authors: Martínez-García Nicole , Melero Royo Sergio Barrionuevo , Marqués Margarita M. , Bayón Yolanda
Published: March 2020

Los editores genéticos, especialmente el sistema CRISPR-Cas9, han supuesto un gran avance para la modificación genética de animales. En el presente artículo, se realiza una revisión de la metodología específica en animales domésticos y sus aplicaciones en Producción Animal y Biomedicina. La parte general sobre la edición genética y el sistema CRISPR-Cas9, ha sido desarrollada en el artículo anterior centrado en las plantas. A pesar de su reciente implementación en la década actual, esta herramienta ha demostrado ya su eficacia en aspectos tan diversos como la resistencia a enfermedades, la mejora de productos de origen animal, o también el uso de animales como biorreactores, modelos de enfermedades humanas o fuente de órganos para xenotrasplante. A pesar de aspectos técnicos que aún deben ser abordados, el sistema CRISPR-Cas9 con su elevada eficiencia y diseño rápido, sencillo y económico, destaca entre las técnicas de modificación genética. Esto lo convierte, en este contexto, en la metodología con mejores perspectivas futuras, no solo para el mundo animal sino también en el ámbito de la salud humana
Exhumación en Canseco (Cármenes, León): Estudio antropológico y paleopatológico
Authors: Serralvo González Miriam
Published: March 2020

En el presente trabajo se expone el estudio antropológico y paleopatológico rea- lizado en tres individuos fallecidos durante la Guerra Civil Española, y exhuma- dos en la localidad leonesa de Canseco. Previo al estudio antropológico, para la facilitación de su análisis, los restos fue- ron dispuestos en conexión anatómica. Los tres individuos eran de sexo masculi- no, de mediana edad y de una estatura en torno a los 165 cm. Una vez finalizado dicho estudio, se llevó a cabo el análisis paleopatológico, de- tectándose hernias discales, nódulos de Schrmöl y entesopatías, así como caries, hipoplasias y alteraciones para-masticatorias. Se destaca la presencia de espina bífida oculta en dos de los individuos; por su ca- rácter genético, pudiendo estar relacionada con procesos de endogamia. Se exponen las posibles patologías causantes de la muerte de estos individuos, todas ellas ocasionadas por armas de fuego y metralla.
Margalef: el último naturalista
Authors: Luis Calabuig Estanislao
Published: March 2020

No resulta frecuente encontrar científicos con acreditada capacidad de excelencia y, al mismo tiempo, que hayan consolidado un cuerpo de doctrina significativo en su área de conocimiento, además de ostentar una completa formaciónhumanística. El profesor Ramón Margalef ha cumplido sobradamente con ambos requisitos, demostrando al mismo tiempo gran eficacia y eficiencia, sirviendo como referencia a la generación de ecólogos del cambio de siglo.
Orinoco: indígenas, peces y mercurio
Authors: Pérez Álvarez Luis Eduardo
Published: March 2020

Durante 39 años vividos en la Orinoquia venezolana acumulé una gran diversidad de experiencias y realizaciones imposibles de comunicar en corto espacio. Pero intentaré una apretada enumeración de algunas. El año 1979, dos meses después de presentar la tesina en la facultad de Ciencias Biológicas de León, me fui a Venezuela. Antes de ingresar como investigador a la Estación de Investigaciones Hidrobiológicas de Guayana de la Fundación La Salle de Ciencias Naturales (FLASA) trabajé como fotógrafo de las páginas sociales de un periódico caraqueño. Después realicé investigaciones en peces (biología, estructura de comunidades, dinámica de poblaciones, uso espacial) y más adelante me moví hacia la piscicultura
La visión de los alumnos acerca de las competencias generales y transversales de los Grados en Biología, Biotecnología y Ciencias Ambientales de la Universidad de León
Authors: García-González Marta Eva
Published: March 2020

El grupo de innovación docente COMBIO (análisis y actualización de competencias en las titulaciones de la Facultad de CC. Biológicas y Ambientales) se creó en2014, en la primera convocatoria de formación de estos GID en nuestra Universidad. Anteriormente el equipo humano constituyente de este grupo, ya había obtenido un PAID (Plan de Apoyo a la Innovación Docente) para trabajaren estos temas (convocatoria PAID-2014). El grupo ha estado formado, a lo largo de su historia, por un total de 11 profesores de distintas áreas de nuestra Universidad, el mayor número de ellos vinculados de alguna manera a cargos de gestión de la Facultad de CC. Biológicas y Ambientales, 4 miembros del PAS y un alumno representante de la Facultad. Hasta el momentohan completado la parte de la investigación relativa a la visión del alumnado acerca de si las competencias transversales y generales que figuran en las Memorias de verificación de los tres Grados de la Facultad se trabajan y evalúan en las distintas asignaturas y han iniciado ya las investigaciones correspondientes a la visión del profesorado de estas asignaturas y la de los egresados de las tres titulaciones.
Noticias de actualidad
Authors: Biológicas y Ambientales Facultad de Ciencias
Published: March 2020

Resumen de la actividad académica realizada en la Facultad de Ciencias Biológicas y Ambientales en el curso pasado
Influence of Employer Brand Image on Employee Identity
Authors: Shaker Fahim , Ahmed A.S. Nooruddin
Published: March 2020

This study aims to provide a framework of understanding the relation between employee identity construction and organization’s employer brand image.  Theoretically, employer brand image and identity construction are two different topics in different disciplines and have evolved separately from each others. The current paper tries to draw a relation between these two topics by addressing research work from employer branding, employee identity construction, literature on the dirty work and so forth.  Drawing this relation is significantly important as in the future it may serve the framework of understanding about certain employee’s positive or negative identity construction influenced by organization’s positive or negative employer brand image. The arguments provided here are typically based on various scholars’ findings relying on classic and contemporary text within organization theory, sociology and marketing. The paper suggests few empirical investigations as future scope of research to provide a concrete understanding of the relation between employee identity negotiation and organization’s employer brand image. JEL Classification Code: M 10; M 12; M 14
Factors Influencing the Adoption of Mobile Banking: Perspective Bangladesh
Authors: Liza Farhana Yasmin
Published: March 2020

With the convergence of banking services and mobile technologies, users are able to conduct banking services at any place and at any time through mobile banking. This research examines the factors influencing the adoption of mobile banking in Bangladesh, with a special focus on trust, perceived cost and perceived risk including the facets of perceived risks: performance risk, security/privacy risk, time risk, social risk and financial risk. The research model includes the original variables of extended technology acceptance model (TAM2). Data for this study was collected through a structured questionnaire survey in townships around Dhaka. The research has found that customers will consider adopting mobile banking as long as it is perceived to be useful and easy to use. But the most critical factor for the customer is cost; the service should be affordable. Trust was found to be significantly negatively correlated to perceived risk. Thus, trust plays a role in risk mitigation and in enhancing customer loyalty.
Does laryngopharyngeal reflux disease impair nasal mucociliary transport? A case control prospective study
Authors: Vasu Pooja K. , Gopalankutty Nayana V. , Somayaji Gangadhara
Published: March 2020

Background: Laryngopharyngeal reflux disease (LPRD) is the retrograde reflux of gastro duodenal contents above the level of upper oesophageal sphincter into larynx and pharynx. LPRD can lead to upper respiratory pathology by direct contact of nasal and nasopharyngeal mucosa with the regurgitated gastric acid. Refluxate can damage the cilia, thereby prolonging the mucociliary clearance time (MCT) and consequently affecting the innate defence mechanism of upper airway. Our objective was to analyse the relationship between MCT and LPRD in patients without any nasal pathology.

Methods: This study was a prospective case control study, with 45 patients each in the study and reference group. Study group included patients with symptoms of LPRD who fulfilled the reflux symptom index (RSI) score of more than 13 points. The reference group included subjects without LPRD, with RSI less than 13. In both groups, conditions causing impaired MCT like allergic rhinitis, sinusitis, rhinitis and history of smoking were excluded. Chronic sinusitis cases were excluded in both groups using sino-nasal outcome test -22 scoring system. Nasal MCT was measured in all these participants using the Saccharin test. Duration more than 20 minutes was taken as prolonged mucociliary clearance time.  

Results: MCT was prolonged in 62% of subjects (28 out of 45) in the study group whereas, in the reference population MCT was normal.

Conclusions: LPRD is a contributing factor for impaired nasal mucociliary transport.
Hospital based study on the effect of flood on change in profile of otomycosis in ethnic Kashmiri population
Authors: Sumbria Deepshikha , Yousuf Aamir , Ahmad Rauf
Published: March 2020

Background: Kashmir valley witnessed devastating floods in the month of September 2014. The target of the study was to assess the changes in clinical profile of otomycosis and fungi responsible for the disease, in-vitro sensitivity of different fungi to various commercially available antimycotic solutions and clinical efficacy of various topical antimycotic solutions in otomycosis in pre and post flood period.

Methods: This study was conducted in the Department of ENT, GMC, Srinagar from February 2014 to July 2015. 152 clinically suspected otomycosis patients were subjected to mycological tests to identify the organism. Clotrimazole, terbinafine, lulliconazole, sertaconazole and combination of 1% clotrimazole, chloramphenicol, beclomethasone was given randomly in equal number of these patients and were followed for 4 weeks. Results of different antifungals were evaluated clinically.  

Results: The trend varies in pre and post flood period. Candida albicans was the most common organism isolated in pre-flood period whereas Aspergillus flavus was the most common organism isolated in post flood period. In the pre flood period Candida and Aspergillus species had equal rate of isolation. However, in post flood period Aspergillus was most common species isolated. Effect of lulliconazole and terbinafine was same in pre and post flood time but serticonazole and fluconazole showed slight variation in effectiveness in post flood period. Clotrimazole and combination of 1% clotrimazole, chloramphenicol and beclomethasone were least effective post flood.

Conclusions: Flood had its impact on profile of otomycosis. A. flavus became more common species in post flood period. It was observed that flood had some impact on drug treatment too but further studies and tests are needed to confirm the effectiveness of drugs on treatment of otomycosis.
Clinical profile and causality of cutaneous adverse drug reactions among patients attending tertiary care teaching hospital in South India
Authors: Mavoori Archana , Bala Sudha , Pamar Sneha , Podila Karunasree , Sriram Deepthi
Published: March 2020

Background: Any undesirable change in the structure or function of the skin and its appendages related to drug eruption regardless of the aetiology is called the cutaneous adverse drug reaction (CADR).  Manifestations are varied with diverse morphological pattern ranging from trivial urticarial to severe form of vasculitis which are fatal. Identifying the culprit drug in this new era with advanced development of multi drugs is a challenging task and can help in prevention of further complications and provide safer drugs. Objective of the study was to assess the clinical profile and causality of CADR among patients in a tertiary care hospital of Hyderabad.

Methods: An observational hospital-based study was undertaken over a 6 months period among patients attending dermatology OPD of medical college and hospital located at Hyderabad. Patients presenting with suspected drug-related cutaneous lesions were included where the drug responsible was ascertained. Drug history was recorded in a format specified in Indian National Pharmacovigilance Programme and causality assessment carried out as per world health organization-uppsala monitoring centre criteria.

Results: The study population consisted of females (52.4%) and males (47.6%). Majority of them were in the age group of 51-60 years. Most common pattern of CADR noted were urticaria (19.05%) followed by erythema multiforme (17.46%) and morbilliform rash (17.46%). The common drugs categorised for these reactions comprised of antibiotics (39%), nonsteroidal anti-inflammatory drugs (26%) followed by anti tubercular treatment (18%).

Conclusions: CADR contribute to significant morbidity among industrial workers and role of pharmacovigilance should be further emphasized to reduce such reactions.  
Role of intralesional vitamin D3 in cutaneous warts: an interventional study
Authors: Kumar Sweta S. , Awasthi Sankalp , Kumar Adesh , Jain Prateek
Published: March 2020

Background: Cutaneous warts are treated primarily with destructive methods such as cryotherapy or electrocautery. These modalities of treatment may be associated with recurrence and scarring in multiple warts. This study aims to evaluate the efficacy and safety of intralesional vitamin D3 in warts.

Methods: 88 patients with recalcitrant warts of varying sizes and duration were included in the study. About 0.2 to 0.5 ml vitamin D3 solution (600,000 IU, 15 mg/ml) was injected to the base of the wart. A maximum of 5 warts were injected per session at 3-week intervals until resolution or for a maximum of 4 treatments. Patients were followed up for 6 months after the last injection to detect any recurrence.

Results: 88 patients completed the study. Complete response was seen in 63 out of 88 (71.5%), partial response in 24 out of 88 (27.2%), and no response seen in one patient. The average number of injections required to achieve a complete resolution was 3.66. Complete resolution of distant warts was noticed in all the patients.

Conclusions: Intralesional vitamin D3 is a safe, effective, and an inexpensive treatment option for recalcitrant warts.

 