bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential and limitations of short backhand serve in badminton: Kinematics analysis
Authors: Irawan Fajar Awang , Ma’dum Mirza Arif , Indardi Nanang , Trans Minh Nghia Le , Fatmasari Annisa Putri
Published: January 2023

Moreover backhand short serve is an important element of the main character in badminton, where not many people can maximize the potential and limits of each athlete, such as power, speed, accuracy, and motion efficiency. This study aims to determine the potential and weaknesses of short backhand serve in badminton through a kinematic analysis approach, with a sample of children aged 12-16 years PB Pendowo Semarang City. The method used quantitative with a descriptive analysis approach, and the analysis is assisted by using the Kinovea 0.9.4 series software. The sampling technique used is purposive sampling with two criteria; age (12-16 years old) and participation in a Semarang city-level tournament. The results showed that the PB Pendowo Semarang City athletes in the implementation phase are in the "Appropriate" category, with a percentage of 66.6%. The instruments used in this data collection are observation and documentation. Several factors that influence the level of conformity are muscle mass, arm length and height, and training intensity. This research can still be developed in future research by discussing more specific things, such as focusing on active wrists and, more specifically, explain about flick movement in the wrist motion. Additional supporting literacy in the backhand short serve analysis could help the athletes and coaches to reach effective movement to get points using the backhand short of serving as the first attack.
Trivium curriculum in Ethno-RME approach: An impactful insight from ethnomathematics and realistic mathematics education
Authors: Prahmana Rully Charitas Indra , Arnal-Palacián Mónica , Risdiyanti Irma , Ramadhani Rahmi
Published: January 2023

In implementing Ethnomathematics-Realistic Mathematics Education (Ethno-RME), teaching mathematics correctly is needed through learning practices in teaching and learning activities. This pedagogical activity requires guidance in the form of a curriculum. So, the teacher can determine the ethnomathematics context as a starting point in teaching mathematics using Ethno-RME. Therefore, this paper focuses on constructing an Ethno-RME curriculum to guide teachers to apply Ethno-RME in their learning process. This research was collected data from a few relevant kinds of literature to build the Ethno-RME curriculum, such as literature about the D’Ambrosio trivium curriculum, the principles, and character of RME, and literature about the implementation of RME and Ethnomathematics in school. Then, the data were reviewed, criticized, and synthesized, which was done by integrating the ideas in the literature with the new ideas to form the new concept and formula for Ethno-RME curriculum. This study comprehensively explains the goal of Ethno-RME learning, Ethno-RME competencies, and the procedure of Ethno-RME learning. Its process consists of several steps: determining, exploring, processing, and finding mathematics in the ethnomathematics context. Furthermore, this procedure continues with conducting self-development models and critical reflection as an assessment.
Ebrûlî Şehir: ‘İslâm Şehri’ Yerine Bir Öneri
Authors: ŞAHİN Yusuf , YILMAZ ASLANTÜRK Arzu
Published: January 2023

Kavramsallaştırma, gerçek hayattaki karmaşık ilişkiler ağını basitleştirerek soyutlaştırma çabasıdır. Dolayısıyla, bir kavramsallaştırmanın başarısı, gerçekliği açıklayabilme kabiliyetine bağlıdır. Weber’le birlikte başlayan ve Şarkiyatçılar tarafından kullanılmaya devam eden “İslâm şehri” kavramının, Müslümanların yaşadıkları şehirlerin gerçekliğinden kopuk bir kavramsallaştırma çabası olduğu ileri sürülmektedir. Zamanla Şarkiyatçılar da “İslâm şehri” kavramına yönelik eleştiriler getirmişlerdir. Ama ilginç bir şekilde kavram, bugüne kadar kullanılmaya devam etmiştir. Bu kavramsallaştırmanın iki açıdan sorunlu olduğu görülmektedir: İlki, bu kavramla, Müslümanların yaşadıkları şehirler ideal bir kalıba dökülmektedir. İkincisi, bu kavramsallaştırma üzerinden Müslümanların yaşadıkları şehirlerdeki bütün sorunlar “İslâm”a havale edilmektedir. Bu çalışmada, “İslâm şehri” yerine, “ebrû sanatı”ndan hareketle “ebrûlî şehir” kavramsallaştırmasına gidilmektedir. Bu bağlamda çalışmanın amacı, Şarkiyatçı bakış açısının standart İslâm şehri kavramsallaştırmaları yerine, içinde barındırdığı etkileşim ve ilintiye bağlı olarak “ebrûlî şehir” üzerinden kavramsal bir öneri geliştirmektir. “Ebrûlî şehir” kavramının, “İslâm şehri” kavramındaki iki eksikliği giderecek nitelikte olduğu düşünülmektedir. Buna göre “ebrûlî şehir” kavramının, Müslümanların yaşadıkları çok sayıda şehrin kendine özgü niteliğini dikkate alabileceği; ayrıca, şehirlerde yaşayan Müslümanların eksikliklerini “İslâm”a havale etme kolaycılığına da mani olabileceği ileri sürülmektedir.
MARTIAL LAW AND VALUE ADDED TAX: PROBLEMATIC ISSUES
Authors: Lohvyn Andrii
Published: January 2023

The article explores problematic issues of a regulatory and legal nature related to the imposition of martial law in Ukraine, which relate to the taxation and ensuring revenues to budgets of all levels, in particular, the introduction of changes in the administration of value added tax, their regulation and compliance from a legal point of view with the realities of today and the needs of taxpayers. The study was carried out based on the general scientific and special methods of scientific cognition. The introduction of the legal regime of martial law necessitated the rapid settlement of issues of constant filling of the state and local budgets. The above-mentioned also implies the use of effective and understandable tax collection procedures by the state, in particular, value added tax. Analysis of the regulatory and legal provisions of the amendments made to the Tax Code shows that the legal norms, governing the procedure for administering value added tax, particularly in terms of the tax credit formation, have an ambiguous interpretation, which leads to a violation of the balance of relations between the entities of legal relations of taxation.
THE PROBLEM OF SUCCESS IN THE FOCUS OF THE PERSONALITY OF A PRIMARY AND SENIOR SCHOOL PUPIL
Authors: Necherda Valeriia
Published: January 2023

The article is dedicated to the problem of success in the focus of the personality of a modern pupil of a general secondary education institution. The tasks of the research are the analysis of theoretical data and the highlighting of the results of empirical research concening the content of the phenomena of success and social success, the content characteristics of the socially successful personality of the pupil, as well as the generalization of the results. In the research process, theoretical methods (analysis, reinterpretation and generalization of data, content analysis) and empirical methods (conversation, blitz survey, method of unfinished sentences) were applied. The author justified the difference between the concepts of «success» and «social success», emphasized the qualities and skills of primary and senior school pupils necessary for social success, and emphasized the importance of creating conditions in the educational environment that contribute to the formation of a socially successful personality.
Antidiabetic activity of ethanol extract of leaves of flax plant (Linum usitatissimum L.)
Authors: S Neelufar Shama  , C Sravanth  , D Pranitha  , D Phaneendra Pavan  , V Ravali  , P Sravan Kumar
Published: January 2023

The aim of the present study was to evaluate antidiabetic activity of ethanol extract of leaves of Flax plant (Linum usitatissimum) in streptozotocin (STZ) induced diabetic rats. Ethanol extract of leaves of Linum usitatissimum (EELL) or glibenclamide was administered to the rats orally daily for 28 days. Blood glucose levels at weekly interval and on 29th day, serum biochemical parameters were carried out to evaluate its antidiabetic effect in diabetic rats. Blood glucose, creatinine, BUN, AST and ALT levels were significantly increased in STZ induced diabetic rats as compared to vehicle control rats. After 28 days administration of EELL showed the significant decrease in above levels as compared to diabetic control rats. The study results suggest that the ethanol extract of leaves of Linum usitatissimum clearly demonstrated the antidiabetic activity in an experimental model of rats.
Surprising benefits of silicon in plants and human beings
Authors: Sunita Arya  , Sonal Verma  , Robina Aman  , Pankaj Kumar  , Anjana Verma
Published: January 2023

Silicon is the second most abundant element on Earth and the third most abundant trace element in human body. It is present in water, plant and animal sources. Silicon is known as a beautifying mineral and there are many health benefits associated with it. It is a macro element involved in the responses of plants to a variety of abiotic stresses. The culture medium composition, particularly the mineral nutrients, greatly impacts the growth as well as the morphogenesis of in vitro plant cultures. Silicon not only helps strengthen connective tissues and bones but is also useful in skin, nail, and hair care. They also play a vital role in the prevention of atherosclerosis, insomnia, tuberculosis, and aluminum toxicity. Silicon and silicic acid may decrease the bioavailability of aluminum by blocking the uptake of the latter by the gastrointestinal tract and impeding its reabsorption in the kidneys. Silicon has also been suggested to be involved in mammalian hormonal control, and protect people from heart diseases, anticancer, anti- atherosclerotic, and anti-diabetic effects.
Dental and Oral Health Education: Effective Ways to Prevent Dental and Oral Health Problems
Authors: Aristiyanto Regia , Harimurti Sabtanti
Published: January 2023

According to Riset Kesehatan Dasar (2018), 57.6% of the Indonesian population have dental health problem. Based on age, the population of 5-9 years (67.3%) were the group with the largest dental problems. The lack of knowledge about dental health was one of the factors that may cause dental health problems, for example, about brushing teeth properly, the percentage was only 2.8%. Based on those data, it was necessary to carry out activities of education about dental health in childhood. Dental health education has been carried out for elementary school students in Srigading Village, Sanden, Bantul, Yogyakarta. The committee was KKN UMY students for the odd semester period 2021/2022. The speaker was a UMY dentistry lecturer who explained dental and oral health, especially related to efforts to prevent dental and oral health problems. Based on the evaluation before and after the implementation of education, it was found that there was an increase in understanding of dental and oral health which was marked by an increase in test scores. An increased understanding of dental and oral health was expected to improve the quality of dental and oral health in childhood.
Effects of Spousal Support in the Early Postpartum Period on Breastfeeding Motivation in Patriarchal Societies
Authors: ULUDAĞ Elif , AYAR Dıjle , BEKTAŞ İlknur
Published: January 2023

Background and Purpose: Breastfeeding is important with regard to public health. Our aim was to examine effects of spousal support in the early postpartum period on breastfeeding motivation in patriarchal societies.
Methods: Study was descriptive, cross-sectional, correlational design. Study was conducted in a University Hospital in Inland Anatolia Region in Turkey. It included primiparous and multiparous women.
Results: Analysis showed a significant positive, moderate relation between spousal support and breastfeeding motivation in the primiparous women; spousal support accounted for 23.8% of breastfeeding motivation of the women. There was a significant, positive weak relation between spousal support and breastfeeding motivation in the multiparous women; spousal support explained 8.2% of breastfeeding motivation in these women.
Conclusion: Spousal support in the early postpartum period was found to have a positive influence on improvement of breastfeeding motivation. However, it could explain a small percentage of breastfeeding motivation. New strategies should be created to encourage spouses to get involved in breastfeeding.
Comparison of the Superiority of Quadriceps Strengthening Isometric and Isotonic Exercises with Respect to Pain, Quality of Life, and Functional Capacity of Patients with Chondromalacia Patellae
Authors: ÖZDURAN Erkan , YILDIRIM GÜZELANT Aliye
Published: January 2023

Purpose: This study aims to investigate the superiority of different exercise modalities, including isotonic and isometric strengthening for quadriceps, over each other and their effect on pain, quality of life and functional capacity in patients diagnosed with chondromalacia patellae (CMP).

Methods: This study was designed as a prospective study in 30 patients(15 patients in isometric, 15 patients in isotonic group) and 15 healthy volunteers aged 20–50 years who were diagnosed with CMP based on physical examination and magnetic resonance imaging and had pain complaints. Pain level was evaluated with Visual Analogue Scala (VAS), functional capacity with Lysholm scale, and quality of life with Short Form-36(SF-36). Q-angle, and thigh circumference were evaluated before and after exercise in all patients.

Results: In patients with CMP, there were significant differences in Q-angle, pain, functional capacity, and some subcomponents of the SF-36 quality of life after performing isometric or isotonic exercises compared with the control group (p0,05). In the evaluation of the isotonic and isometric exercise groups, there were no significant difference in the assessment of Q-angle, thigh circumference, pain, functional capacity, and quality of life of patients with CMP (p>0,05).

Conclusion: Isometric and isotonic quadriceps strengthening exercises are not superior to each other in terms of pain, functional capacity, and quality of life in CMP treatment.
Healthy Lifestyle Behaviors and Perceived Prenatal Stress in Obese Pregnant Women
Authors: AKGÜNEŞ DALKILINÇ Aygül , EGELİOĞLU CETİŞLİ Nuray
Published: January 2023

Purpose: The study was conducted to examine healthy lifestyle behaviors and perceived prenatal stress level and affecting factors in obese pregnants.

Material and Methods: This cross-sectional study was conducted with 159 obese pregnants with a gestational age of 37 weeks and above, with a BMI of 30 and above, who applied to the obstetrics clinic of a university hospital in Izmir between December 2020 and July 2021. Data were collected using the Individual Identification Form, the Prenatal Perceived Stress Scale and the Healthy Lifestyle Behaviors II Scale.

Results: It was found that the Healthy Lifestyle Behaviors II Scale mean scores of the obese pregnants included in the study were low and their perceived prenatal stress levels were high. It was determined that there was a negative, significant and high correlation (r= -0.715; p= 0.000) between the mean total score of the Healthy Lifestyle Behaviors II Scale of obese pregnants and the mean scores of the Prenatal Perceived Stress Scale.

Conclusion: With a multidisciplinary team, care should be given to obese pregnants to gain healthy lifestyle behaviors and to avoid or manage stress.
Is the Occurrence of Gestational Diabetes Mellitus in Pregnancies Higher Following In Vitro Fertilization Treatment? Why? A Retrospective Cohort Study
Authors: AYPAR AKBAĞ Nuran Nur , ALUŞ TOKAT Merlinda , FATA Sevcan , ÜNSAL AVDAL Elif , OKYAY Emre , DOĞAN Ömer Erbil
Published: January 2023

Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk.

Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The data were obtained from medical records and phone interviews. Univariate and multivariate logistic regression analyses were performed.

Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95% CI = 1.07–11.23, p= .038).

Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.
The Awareness of Healthy Individuals about Attributable Risk Factors of Cancer
Authors: KESER İlke , ÖZDEMİR Kadirhan , UTKAN BERGÜZ Hilal , ATASAVUN UYSAL Songül , SUNER-KEKLİK Sinem , BAGLAN-YENTUR Songul , ARAS Mukaddes
Published: January 2023

Background and Purpose: This study aimed to determine the awareness of healthy individuals about the attributable risk factors of cancer and the reliability of their ideas.

Methods: A review of relevant literature was undertaken to assemble a list of possible causes of cancer. Seventy-six healthy individuals were interviewed. Individuals were asked to declare their opinion by scoring the potential 15 cancer risk factors between 0-4. One week later, the opinions were retaken to test reliability.

Results: According to the participants, smoking (94.8%) and mobile phone use (79%) had perfect consensus; being overweight (63.1%) and having a family history of cancer (92.1%) had substantial consensus; alcohol (90.8%), stress (93.5%), sunlight exposure (69.77%), plastic (84.2%), infection (57.9%), occupational exposure (67.1%), fatigue (54%), nuclear accident (96%) had moderate consensus. Air pollution (86.8%) and washing agents (77.7%) had fair consensus. Age (34.2%) was not a risk factor for cancer. All risk factors were reliable between the two assessments except age (p
A Comparison between Healthy Lifestyle Behaviors and Physical Activity Levels of Elderly İndividuals Residing in the City Center and Rural, and Analyzing Their Relationship with Depression
Authors: KÖROĞLU Fahri , ERSÖZ HÜSEYİNSİNOĞLU Burcu , UZUN Nejla , KURTARAN Mehmet , VURAL ŞENYURT Meltem , ŞEKER ABANOZ Ebru
Published: January 2023

ABSTRACT

Purpose: Our study aimed to determine the differences in the levels of physical activity and healthy lifestyle behaviours in elderly individuals living in urban and rural and to examine their relationship with depression.

Methods: Individuals who are over 65 and residing in the city and rural were included in the study. The Healthy Lifestyle Behaviour’s Scale-II, the Physical Activity Scale for the Elderly, and the Geriatric Depression Scale-15 were used on the participants

Results: Healthy Lifestyle Behaviour’s Scale-II scores was no significant difference between the two groups (p=0.430). Physical Activity Scale for the Elderly score in rural (p= 0.001); Geriatric Depression Scale-15 score was statistically higher in the city (p= 0.01). While the relationship between the Healthy Lifestyle Behaviour’s Scale-II and Geriatric Depression Scale-15 scores was significant in both groups (p= 0.001 and p= 0.03), the relationship between the Elderly Physical Activity Scale-II and Geriatric Depression Scale-15 scores was significant only in the rural (p= 0.001).

Conclusion: The elderly individuals in rural are more physically active than in city, the elderly living in city have higher depression levels. The factors affecting depression in the elderly living in cities need to be examined in detail.
Gender Differences in Gait Parameters of Healthy Adult Individuals
Authors: SUNER-KEKLİK Sinem , ÇOBANOĞLU Gamze , ECEMİŞ Zeynep Berfu , ATALAY GÜZEL Nevin
Published: January 2023

Background and Purpose: Anatomical and biomechanical differences between male and female are also known to cause differences in gait patterns. However, the results of the studies are contradictory. Furthermore, these studies focused only on some of the spatiotemporal parameters, and pelvic movements were not analyzed. The aim of the present study is to reveal the difference in gait parameters between male and female. Methods: 44 female and 39 males were included in the study. BTS G-Walk system was used to evaluate the gait. After the accelerometer was placed, the participants were asked to walk 8 m. Spatiotemporal parameters and pelvic kinematics were recorded. Results: Given the spatiotemporal parameters, it was found that male and female were similar in terms of speed, % stride length and step length (p>0.05), while gait cycle duration, stride length, swing phase and single support phases were higher in male; and stance phase, first double support phases, cadence were found to be higher in female (p0.05), while pelvic tilt total range was higher in male and obliquity total range was higher in female (p
What Factors Affect Treatment Effectiveness in Rheumatoid Arthritis: A Multidimensional Measurement
Authors: İLGÜN Gülnur , ŞAHİN Bayram
Published: January 2023

Purpose: The aim of the study was to examine the effects of socio-demographic characteristics, disease-related characteristics and health care use related-characteristics on the treatment effectiveness of rheumatoid arthritis patients, both separately and together.

Methods: The sample of the study consisted of 440 rheumatoid arthritis patients for 99% confidence level, and this sample was reached based on the convenience sampling method. Patients who received at least one anti-TNF therapy were included in the study. Treatment effectiveness levels of rheumatoid arthritis patients were measured with a questionnaire. In the analysis of the study, four different regression models were established. In the first model, socio-demographic characteristics; in the second model, disease characteristics; in the third model, health care use characteristics: in the fourth model, the effect of all these variables on treatment effectiveness was examined.

Results: In the study, smoking status, age (socio-demographic characteristics), drug regimen complexity, comorbidity status, education about the disease, disease duration (disease characteristics), and a number of admissions (health care use characteristics), were found to have a significant effect on treatment effectiveness.

Conclusion: In the study, the factors affecting the treatment effectiveness were determined. Therefore, it is important to consider these factors revealed in this study in order to increase the treatment effectiveness in patients with rheumatoid arthritis.
Determination of Career Choices and Reasons for Intern Physicians at Dokuz Eylul University Faculty of Medicine
Authors: SÜNER Ahmet Furkan , IŞIK Elif , ŞİMŞEK KESKİN Hatice
Published: January 2023

Purpose: In this study, it was determined the characteristics and reasons of career choices of intern physicians who are educated at Dokuz Eylul University Faculty of Medicine in the period 2021-2022.

Material and Method: This descriptive study was conducted between August 2021 and February 2022 at the Dokuz Eylul University, Faculty of Medicine. The data were collected online through Google forms with a previously experimented questionnaire. 272 intern physicians answered the questionnaire (reach rate = 83.4%).

Results: Only 27.0% of the intern physicians stated that they wanted to work in the deprivation area, while 89.3% of them thought of becoming a specialist after graduation. 30.9% of the intern physicians stated that they wanted to work at a university after graduation, and 25.7% of them thought of a career abroad. The three departments most frequently stated by interns to write to their first choice are psychiatry (9.4%), dermatology (6.8%) and ophthalmology (6.8%). The first five factors that intern physicians answered as "very influential" on the choice of profession, acceptable working hours (84%), working conditions after specialization (82.9%), occupational satisfaction (78.4), violence against healthcare workers (74.3%), specialization training. conditions (73.6%).

Conclusion: Specialization is the most important career option for medical students after graduation. It is seen that acceptable working hours, working conditions after specialization, job satisfaction, violence against healthcare workers, conditions of specialization training, malpractice lawsuits and high-income opportunities are effective in the selection of specialization.
Effect of Mothers' Parental Bonding Style on Their Maternal Attachment
Authors: ÖZTAŞ Duygu , ER KORUCU Aslı , USLU ŞAHAN Fatma
Published: January 2023

Purpose: This study was aimed to investigate the relationship between mothers’ parental bonding styles and their maternal attachment levels. Methods: This descriptive and cross-sectional study involved 216 mothers. The data were collected using the Personal Information Form, the Maternal Attachment Inventory (MAI), and the Parental Bonding Instrument (PBI). Results: The mean MAI score of the mothers was found to be 96.72 ± 8.75 which indicated a high level of maternal attachment. The mean score from the PBI-mother form was found to be 49.13 ± 14.60 and PBI-father form was 46.12 ±14.90 which indicated that the mothers had a positive bonding with their parents.The relationship between an individual’s maternal attachment was found to be positive, moderate, and significant to her own parental bonding. Parental bonding with mother and parental bonding with father explained 35% and 23% of the total variance found in maternal attachment, respectively. Conclusion: Mothers’ parental bonding showed an effect on their maternal attachment as well. The families and couples should be trained on how positive or negative bonding with their children can affect their life cycles and future lives.
Determination of Multiple Cancer Risk Behaviors Among Adult Population in Turkey: A Cross-sectional Study
Authors: İPEK ŞIKLAROĞLU Merve , TUZCU Ayla
Published: January 2023

Background: Modifiable cancer risk behaviors are general not seen alone but in combination in individuals.

Purpose: This study aims to investigate the factors associated with combinations of cancer risk behaviors, including tobacco use, obesity, and low physical activity that cause cancer in adults.

Methods: A total of 720 adults were selected using the multi-stage cluster sampling method. Data were collected using the World Health Organization STEP-wise protocols.

Results: It was found that 46.9% of the participants showed one, 46.3% two or more types of risk behavior. The percentage of married individuals was higher among those who engaged in one, two, or three risky behaviors than those who did not engage in risky behaviors. Among participants with two risk behaviors, the percentage of those who rated their health as very good was lower than those without risk behaviors; those who had friends or relatives with cancer were high. Those who engaged in three risk behaviors were less educated and had lower incomes than those who did not engage in risk behaviors.

Conclusions: Health intervention strategies should be increased in primary health care institutions for individuals who are married, has low level of education and income and has weak perception of health.
Novel Approach to the Hedgehog Signaling Pathway: Combined Treatment of SMO and PTCH Inhibitors
Authors: KARADAĞ Aslıhan , BAŞBINAR Yasemin
Published: January 2023

Purpose: Abnormal Sonic Hedgehog signaling Pathway (Shh) activation is crucial for development of cancer stem cells, neoplastic growth and epithelial-mesenchymal transition processes in adulthood. Activation of Hedgehog signaling pathway may induces the changes in cilia found in the cell membrane, iniciates the Gli1 transcription factor that is translocated to the cell nucleus and finally, the target genes are transcribed. In this study, invastigation of the antiproliferative, anti-invasive and antimigrative effect of the combined use of robotnikinin (Ptch1 antagonist) and vismodegib (Smo inhibitor) on the hedgehog signaling pathway was aimed.

Material and Methods: After demonstarting the presence of the hedgehog signaling pathway in the glioblastoma cell line U87-MG, the effect of the combined use of the robotnikinin and the vismodegib on the hedgehog signaling pathway was investigated. In-vitro cell proliferation, migration, and invasion analysis of the combination of antagonist and inhibitor and in silico drug-likeness analysis were performed.

Results: Two different combinations of robotnikinin and vismodegib were tested. In vitro studies show that the combined use of agents in combined treatments of Smo and Ptch1is more effective than their individual usage.

Conclusion: Inhibition of the hedgehog signaling pathway with specific inhibitors and antagonists is considered an innovative strategy for cancer therapy.
Tristar Vessels: A Newly Described Dermoscopic Vessel Pattern of Miescher’s Nevus
Authors: AVCI Ceylan , AKARSU Sevgi , ÖZBAĞCİVAN Özlem , FETİL Emel , GÜNEŞ Ali Tahsin
Published: January 2023

Purpose: Although it is very common in people over 30 years old, little is known about the validity of dermoscopic criteria to differentiate Miescher’s nevus (MN) from other papulonodular lesions located on the head and neck. The aim of this study is to evaluate the dermoscopic findings in MN on the head and neck in patients over 40 years by using dermoscopy. Methods: In this descriptive cross-sectional study 170 MN were evaluated by using polarized light dermoscopy. frequencies of dermoscopic findings in MN were determined using Statistical Package for Social Sciences for Windows 15.0. Results: The most frequently detected dermoscopic pattern in MN was globular pattern (64.5%), less often homogeneous (32.4%) or cobblestone pattern (2.9%). Globules were observed in 75.3% of MN and dots were seen in 12.4%. They frequently had skin-colored (87.1%) or light-brown (49.4%) homogeneous structureless areas. Elongated comma vessels (47.1%) were the most common vascular findings. Although comma vessels (33.5%) and linear vessels (4.7%) were also observed, 11.2% of MN presented “tristar vessels” (a newly described vascular pattern) that showed regular ‘tristar like ramifications’ in the distal part of the vessels. Conclusions: Firstly identified “tristar vessel pattern” is a dermoscopic description of MN that can be a useful clue to differential diagnosis.
Pendampingan Trauma Healing dan Edukasi Bencana Pada Anak-Anak Korban Bencana Banjir di Kelurahan Kasunyatan Kasemen Kota Serang
Authors: Firdausi Indrianti Azhar , Mulyasih Rahmi , Santi Endang Tri , Marthalena  , Mardiana Siska , Pitasari Dwi Nurina , Annisarizki  , Rizka Dwi , Putri Liza Diniarizki
Published: January 2023

Dalam kegiatan pengabdian masyakat ini bertujuan untuk memberikan edukasi sekaligus hiburan (entertain) pasca bencana banjir yang terjadi hampir di seluruh wilayah kota serang pada Mei 2022. Bencana banjir yang melanda di Kota Serang mengakibatkan banyak kerugian secara fisik maupun non fisik. Kerugian non fisik meliputi trauma pada anak-anak yang pertama kalinya merasakan bencana banjir yang cukup besar. Pasca bencana banyak korban yang kehilangan harta benda serta fasilitas umum seperti sekolah, madrasah dan perkantoran yang tidak dapat digunakan sementara waktu. Tujuan pengabdian ini bertujuan memberi dukungan pendampingan serta edukasi tentang bencana banjir untuk mengurangi gangguan psikologis yang sedang dialami anak-anak. Metode yang digunakan dalam kegiatan pengabdian masyarakat ini dengan terapi bermain, story telling dan edukasi bencana. Hasil kegiatan adalah penyembuhan trauma pada anak-anak perlu proses berkesinambungan dengan cara mengajak bermain, berbagi rasa, dan menyampaikan informasi terkait apa yang mereka alami saat itu sehingga tujuan dari kegiatan ini tercapai dengan hilangnya rasa takut dan melupakan kesedihan atas trauma yang dialami
Specifics of the Post-Soviet Period of Development of Belarus in the Light of A.A. Zinoviev’s Ideas
Authors: Lazarevich Anatoly A.
Published: January 2023

The article examines features of the post-Soviet period of social transformation and state building of Belarus in the context of the comparative analysis of the Soviet (communist) and Western (capitalist) development systems conducted by the famous Russian philosopher and sociologist Alexander Zinoviev. The author pays attention to the reasons of the collapse of the USSR, according to A.A. Zinoviev, as well as to the search by the post-Soviet countries, including the Republic of Belarus, for their own ways out of the current crisis. The author states that the most important task of gaining state sovereignty is associated not only with social and economic processes but also with the field of national self-consciousness and the specifics of the formation of national and cultural identity. This cause is related, among other things, with the national philosophy as a stable basis of intellectual cultural creation, the evolutionary formation of worldview and cultural values of people. The author demonstrates a tolerant nature of this process in Belarus which made it possible to avoid acute social conflicts in the country and to avoid the opposition of the Belarusian model of development and culture to the traditions and achievements of neighboring countries and the world civilizational process as a whole. Also the author demonstrates contemporary achievements of the Republic of Belarus in the sphere of socio-economic and scientific-technological development as the basis for further modernization of the country in new geopolitical conditions. The conceptual views of A.A. Zinoviev are multifaceted, they have contributed and continue to play an important role in science, culture, social development, socio-political practice. Zinoviev’s works are very valuable since they are still actual and serve as a good theoretical, ideological, and methodological basis in assessing modernity, including understanding socio-political processes that have developed today in the post-Soviet space, around Russia and Belarus, in relations between the West and the East.
The Crisis of Democracy and the Problem of Democratic Peace
Authors: Sidorenko Irina N.
Published: January 2023

The author analyzes three waves of the crisis of democracy during the 20th and early 21st centuries. The first crisis of democracy in the early 20th century is caused by the emergence and development of public politics, which challenged the possibility to govern the masses having conflict potential, it balanced the power of the people and universal suffrage with the control of the media in order to maintain the stability of political system. The second wave of the crisis of democracy (the last third of the 20th century) is associated with the destruction of the conventional world and the weakening of the nation-state; and its markers were: the imbalance between the branches of government, the domination of economics over politics, the predominance of equality over freedom, the problematic implementation of human rights, and, as a consequence, the inability to put into practice the national form of democracy. The third wave of crisis (early the 21st century) is accompanied by the transformation of democracy into post-democracy, in which the power of the people is replaced by the power of global capital, and the illusion of consent is reinforced by the prohibition of alternative points of view and the narrowing of the space of issues allowed for discussion in the name of public security. The crisis of the policy to achieve peace through the transformation of the balance of powers into a balance of interests called into question the principles of democracy. On the contrary, post-democracies justify the use of force to spread democracy around the world, and they take an active part in contemporary military conflicts, which can rightly be defined as hybrid proxy wars. Drawing on J. Habermas’s concept of communicative rationality, the author concludes that to overcome the crisis of democracy it is necessary to accept the very possibility of an alternative to this form of government and allow to discuss these previously marginalized issues as well as to maintain the return of the majority to genuine communication and politics, contribute to its enlightenment.
ANALYSIS OF METHODS AND DEVELOPMENT OF THE CONCEPT OF GUARANTEED DETECTION AND RECOGNITION OF EXPLOSIVE OBJECTS
Authors: Fedorenko Gennadiy , Fesenko Herman , Kharchenko Vyacheslav
Published: January 2023

The subject of the article are the methods of detection and recognition of explosive objects. The aim of the work is to develop the main provisions of the concept of guaranteed detection and recognition of explosive objects. The following tasks were solved in the article: an analysis of existing approaches to the use of traditional single and combined, as well as non-traditional (biological) methods of detecting explosive objects, development of a classification table of methods of detection of explosive objects according to physical principles, analysis of advantages and disadvantages of the considered methods of detection of explosive objects, development of comparative table methods of detecting explosive objects, formulation of the introductory provisions of the concept of guaranteed detection and recognition of explosive objects. The following methods are used – methods of comparison, methods of abstraction, methods of analysis and synthesis, methods of scientific induction. The following results were obtained – an analysis of the features of the existing traditional and non-traditional (biological) methods of detecting explosive objects was carried out. A classification of methods for detecting explosive objects is proposed, taking into account the parameters that affect the probability of detection and productivity. The results of a comparative analysis of explosive object detection methods are presented in tabular form according to the following indicators: type of interaction with explosive objects, platform type, potential productivity, information technology support, quality parameters, and economic indicators. The main provisions of guaranteed detection and recognition of explosive objects are formulated. Conclusions: the low productivity of the existing methods does not allow for quick and effective clearing of the territory contaminated by explosive objects, which leads to a large number of injuries and deaths of people due to the detonation of explosive objects. The use of individual detection methods alone cannot significantly increase the probability of detecting explosive objects. To increase the productivity and safety of the search and disposal of explosive objects, it is advisable to use unmanned intelligent platforms to deliver information and measurement tools.
Educating Effervescent Women Scientists through Lucy Maud Montgomery's Anne of Green Gables
Authors:   Universiti Tenaga Nasional, Chong Seng Tong , Jin Ng Yu ,   Universiti Tenaga Nasional, Karthikeyan J ,   Vellore Campus, Mohd Kasim Zalina ,   Universiti Putra Malaysia, Yee Lee Su ,   Infrastructure University Kuala Lumpur
Published: January 2023

The series Anne of the Green Gables is sequential children books that focus on Anne Shirley, the story's protagonist. The series of books explore Anne's life from a girl to a charming pretty young lady. In the story, Anne is portrayed as an inquisitive young girl. She explores her life philosophically. She also explores many aspects of nature and its relation to science. Her inquisitiveness is extremelysharp, that the skill helps her in learning the science of everyday life. The paper discusses Anne of the Green Gables' use in educating female students to enjoy STEM education. At present, the proportion of women engineers in Malaysia is disproportionate, and the Ministry of Education is working on inculcating female students' effervescence in STEM subjects. The methodological framework utilised in this study adhered to the approach of the phenomenological case study's paradigm. Interviews were conducted,and qualitative data were gathered and analysed using Atlas.ti, a qualitative data analysis software. The findings indicated that female students could draw links between themselves and Anne, the protagonist in the novels. The protagonist's various occupational explorations helped female students understand that they can excel in STEM and arouse their interests to become scientists or engineers. In conclusion, the use of literary texts written by female authors such as Anne of Green Gables could draw attention from female students towards STEM. This study fills the gap in the existing literature where no scholars have used the classic Anne of Green Gables to illicit interests among young female students.
Reading Habits and Attitudes Among University Students: A Review
Authors:   Universiti Tun Hussein Onn Malaysia, Alsaeedi Zubaidah Sadeq , Binti Md. Ngadiran Nurizah ,   Universiti Tun Hussein Onn Malaysia, Abdul Kadir Zulida ,   Universiti Tun Hussein Onn Malaysia, Altowayti Wahid Ali Hamood ,   Universiti Tun Hussein Onn Malaysia, Al-Rahmi Waleed Mugahed ,   King Saud University
Published: January 2023

Reading is the core element in the learning process. Reading habits and attitudes towards reading is one of the primary concerns in the field of education. Researchers report a pattern of low reading habits and attitudes among university students. This paper aims to review the latest literature on reading habits and attitudes among university students. The scope of this literature review was extracted from journal articles and electronic media on the subject of reading habits and attitudes.
Language learning and technology: A conceptual analysis of the role assigned to technology
Authors: Zheltukhina Marina R. , Kislitsyna Natalia N. , Panov Evgeny G. , Atabekova Anastasia , Shoustikova Tatyana , Kryukova Nina I.
Published: January 2023

As technology advances, the teaching-learning process becomes more robust. In addition to technological possibilities and opportunities, the functions that academics give to technology have an impact on its effective application in the field of education. In this study, it is intended to investigate technologically based studies in the field of English language instruction. The study evaluated research articles published in the journals "Language Learning & Technology" "The Journal of the European Association for Computer Assisted Language Learning" and "Computer Assisted Language Learning" in 2020 and 2021 and indexed by the Web of social science. The articles were thematically analyzed. Examined were the study's objective, methods and approaches, technological instruments, and data collection tools. The primary factor is how technology is utilized in the study. Particularly in language education, the role of technology in teaching English as a second language has been investigated. Technology helps EFL students learn. This study will try to conceptualize technology's role. Technology is supposed to develop writing and language abilities first. Quantitative research predominated, followed by mixed-methods. Most research sampled college students. The study mostly used learner-centered and task-based instruction. Language-learning websites are chosen. Second-tier mobile apps. Technological tools are employed directly as teaching tools individually or in groups, but their use as a communication tool between students and teachers and as a tool for student cooperation is highlighted.
Introduction of an additional source of harmonic signal into the circuit of the electric power resonant amplifier
Authors: Batygin Yuriy , Shinderuk Svitlana , Chaplygin Evgen , Yeryomina Olena , Tereh Egor
Published: January 2023

Problem. The problems of the electric power industry, caused by the depletion of the natural resources of the planet and the need to replace them, initiate the development of new physical and technical solutions with the practical use of the known natural phenomena. Goal. The purpose of this work is to propose to introduce an additional source of a harmonic signal (voltage or current) into the circuit of a resonant amplifier of electric power, to obtain calculated analytical dependencies for numerical estimates of the characteristics of ongoing electromagnetic processes, which make it possible to give a fundamental justification for the real performance of the proposed circuit as a whole, taking into account the interaction of all its functional components. Methodology. This work, ultimately, involves the use of resonant phenomena in circuits with active-reactive elements and their theoretical analysis using the mathematical apparatus of the theory of electrical circuits. Results. It is proposed to implement the resonant amplifier circuit in the form of four active-reactive closed circuits inductively coupled to each other. Moreover, in a practical embodiment, inductive couplings can be carried out using HF ferrites. The first circuit is the input circuit with the harmonic power source to be amplified. The second circuit generates amplified reactive power in the "voltage resonance" mode. The third circuit with an additional harmonic voltage source outputs reactive power from the second circuit in the "current resonance" mode. The fourth circuit, inductively coupled to the third circuit, contains the output load of the entire resonant amplifier. This is a resistor that simulates the release of active power. Originality. Physically, the introduction of an additional source in the third circuit is equivalent to the creation of a "negative active resistance", which makes it possible to create conditions for excitation of current resonance with the minimum possible distortion and, ultimately, to reduce the reverse effect on the amplifying processes in the second circuit (reactive power amplifier). The analysis and numerical evaluation of the characteristics of the proposed scheme of the active electric power resonant amplifier showed its fundamental viability. Practical value. As an example, calculations of currents and voltages in the circuit of an experimental model were made, which enabled to formulate recommendations for the selection of elements of a real active electric power amplifier with high efficiency for low-resistance output loads.
Two inverse non-stationary problems of axially symmetric deformation of a finite-length elastic cylindrical shell
Authors: Voropay Alexey , Povaliaiev Serhii , Sharapata Andrey
Published: January 2023

Among the many problems of the solid mechanics, there is a whole class of problems that are related to inverse problems. In turn, among the inverse problems, many problems are ill-posed. Obtaining an exact analytical solution of such problems is related to certain mathematical difficulties and requires using special methods. Goal. The goal of the study is to obtain analytical solutions for inverse problems of the identification of non-stationary load and the control of non-stationary vibrations of a cylindrical shell with asymmetric boundary conditions. Methodology. In this investigation, a refined theory of medium-thickness shells was used. Fourier series expansion, the theory of integral equations and the Laplace transform were used to obtain the solution of the direct problem. Tikhonov’s regularization method was used to solve inverse problems. Results. As a result of the investigation, the solutions of two inverse problems of the solid mechanics were obtained. The first task is to identify a fixed and moving concentrated axisymmetric non-stationary force acting on a cylindrical shell, based on the displacement values at any point of the shell; identification of two fixed concentrated forces. The second task is to control vibrations at any point of the cylindrical shell by introducing an auxiliary concentrated force. Numerical results obtained demonstrate the fulfillment of the control criterion as a result of the action of the given and auxiliary force. Originality. Analytical solutions of the inverse problems of the solid mechanics for a cylindrical shell of medium thickness with asymmetric boundary support conditions are obtained. Practical value. The technique received allows effective identification of an unknown non-stationary load. It’s important for the rational design of reliable cylindrical shell structures. Its use also makes possible to create a theoretical basis to control the deflected mode parameters of cylindrical shell structural elements