bluuebunny/crossref_metadata_2025 huggingface dataset:
INSTITUTIONAL ENSURING THE ESTABLISHMENT OF THE KNOWLEDGE ECONOMY IN UKRAINE
Authors:   Chernihiv Polytechnic National University, Kharchenko Yulia
Published: April 2023

In the author's article, the historical prerequisites and modern challenges of the institutional development of the knowledge-based economy, which appeared before Ukraine due to military actions on its territory, are highlighted.It is assumed that innovations provoke positive structural changes in the economy and society, affect the productivity of the economy, contribute to its competitiveness in the global environment and ensure sustainable rates of regional development in the future. The author notes that for many years there has been no effective innovation strategy in Ukraine that would be recognized and satisfy all categories of modern innovators and expert communities, and today, the war has every chance to finally destroy the remaining remnants of science and innovation. But he emphasizes that the reasons are important prerequisites for the wide implementation of innovations in modern society. Indicates that thanks to the analysis of opportunities for improving not only the technological processes of the production of goods and services, and the institutional structure of society, one can hope for the improvement of the system, state administration, modernization of productive forces, regional development and the legal field for all aspects of human life and civil society, which is our scientific search.The article notes that a distinctive feature of the new phase of technological development of mankind is increased attention to knowledge, as the latter increasingly manifests itself in the formof a direct productive force.The article states that in the conditions of the transition to the knowledge economy, a new generation of teachers should be trained, who should first of all master new technologies in the conditions of mass informatization of society.
EVALUATION OF THE STATE ENERGY SECURITY MANAGEMENT PROCESS: METHODOLOGICAL ASPECT
Authors:   National University «Yury Kondratyuk Poltava Polytechnic», Shchurov Igor
Published: April 2023

In the conditions of a changing environment, the assessment of the state's energy security management process is an important component of ensuring the sustainability and stability of the state's energy system. Effective assessment involves the application of system methods and assessment tools that will allow to determine potential threats, security requirements, risks and vulnerabilities of the energy system. Therefore, some methods are based on the development and use of key indicators of management efficiency, which allow monitoring the dynamics of the development of the energy system and identifying opportunities for improving its condition. Others are based on the analysis of threats and weaknesses of the energy system, which allow to identify potential threats to the energy system, assess the probability of their occurrence and establish the level of risk. Considering today's challenges, the search for the most effective methodology for evaluating the state's energy security management process deserves special relevance.To systematize methods for evaluating the state's energy security management process and propose the most effective of them, which will make it possible to recommend it for use at the state level. In the research process, such methods as grouping were used, which made it possible to distribute indicators according to the main groups of methods; scientific abstraction -to highlight themain methods; comparison -to determine the methodology that most fully reflects the real state of energy security of the state.The methods of assessment of the state energy security management process have been studied. It was determined that the assessment of the state's energy security management process is a complex task that requires the use of various methods and approaches. Methodologies for evaluating the state's energy security management process have been systematized. The methods of integral assessment, economic analysis, identification of the level of energy security, methodological advice and identification of threats are highlighted. It has been established that each of these methods has its advantages and disadvantages, and the choice of a specific one of them depends on the task, the object of research and the available information. Attention is focused on the importance of ensuring the reliability and objectivity of the obtained results, which can be achieved through the use of relevant data and information, as well as the application of scientific methods and standards.
The spread of a new coronavirus infection (COVID-19) in the conditions of Russian penitentiary institutions: the state and counteraction measures
Authors: Egorova T. I.
Published: April 2023

The article examines the peculiarities of the spread and counteraction of the new coronavirus infection in Russian penitentiary institutions. Special attention is paid to the issues of keeping suspects, accused and convicted persons in isolation, as well as related recommendations of the Supreme Court of the Russian Federation. The results of the study of the order and conditions of isolation in Russian penitentiary institutions, together with somatic indicators of the age and health of persons held in them, give grounds for reasonable alarm about the existence of increased risks of the spread of COVID-19. However, practice shows that timely sanitary and epidemiological measures taken by the state and special restrictions of a regime nature in isolation have restrained the spread of the disease. Conclusions are drawn about the need to change some provisions of the Criminal Code of the Russian Federation, the Criminal Procedure Code of the Russian Federation and the penal enforcement legislation to ensure the possibility of urgent correction of criminal policy and law enforcement in conditions of high readiness for natural and man-made emergencies.
Intramedullary hemangioblastoma of the thoracic cord with a microsurgical approach: A case report and literature review
Authors: Piovesan Eduardo Cattapan , Petry Silva Werner , Mallmann Adroaldo Baseggio , Lanzini Felipe Severo , Zanatta de Freitas Bruna , Lemanski Francisco Costa Beber , Carazzo Charles André
Published: April 2023

Background:

Spinal cord hemangioblastomas (HBs) account for 2–15% of all spinal cord neoplasms. They are the third most common primary intramedullary tumor (1–5%). Here, 72-year-old female presented with a thoracic intramedullary spinal HB that responded well to surgery.

Case Description:

A 72-year-old female presented with a 3–4 years of progressive paresthesias and paraparesis. On examination, she exhibited diffuse distal weakness of the lower extremities. The magnetic resonance scan showed an intramedullary expansive lesion at the T1–T2 level that markedly enhanced with contrast with both proximal and distal hydromyelia. Surgery included a C7 partial and T1–T2 total laminectomies performed under microscope visualization with intraoperative monitoring. At surgery, there was a well-documented cleavage plane between the tumor and the cord; excision was facilitated using the cavitron ultrasonic surgical aspirator device.

Conclusion:

Surgery is the gold standard treatment for treating/resecting HBs and should include utilization of an operating microscope and intraoperative monitoring.
The study of "qualitative words" based on the material of fiction
Authors: Бахаева Л.М. , Муратова Е.Н.
Published: April 2023

Статья посвящена изучение качественных прилагательных на материале художественных произведений. В последние время в научной картине мира особый интерес приобретает антропологическая лингвистика. Решаются вопросы о том, как отражается в языке человек. Образ персонажа позволяет обсуждать проблему реконструкции человека с опорой на данные языка. Обучить воспроизвести качество, охарактеризовать его, точно и метко подбирать из ряда эпитетов один самых выразительных, говорить кратко, но убедительно, – вот главные задачи, которые встают перед учителем в работе над темой «Прилагательное» и которые решать надо на протяжении всего обучения. Важно для развития речи ознакомить учащихся с прилагательными в прямом и переносном значении. «Качественные слова» – самая живописная часть речи. Обращение к прилагательным диктуется необходимостью в деталях обрисовать внешность героя.

The article is devoted to the study of qualitative adjectives based on the material of artistic works. Recently, anthropological linguistics has become of particular interest in the scientific picture of the world. Questions are being solved about how a person is reflected in the language. The character's image allows us to discuss the problem of human reconstruction based on language data. To teach to reproduce the quality, to characterize it, to accurately and aptly select one of the most expressive epithets from a number of epithets, to speak briefly but convincingly – these are the main tasks that the teacher faces in working on the topic "Adjective" and which must be solved throughout the entire training. It is important for the development of speech to familiarize students with adjectives in direct and figurative meanings. "Quality words" are the most picturesque part of speech. The appeal to adjectives is dictated by the need to describe the appearance of the hero in detail.
Essential and fundamental surgical suture techniques for aseptic rodent surgery
Authors: Nair Revathi R , Achari Sharabu Lokeswara , Sharma Roma , Thomas Peter , R Pragadeeshwara Rao
Published: April 2023

Suture techniques have been used since ancient times and play an important role in achieving haemostasis during surgery. By carefully suturing blood vessels, surgeons can effectively control bleeding and minimize the risk of haemorrhage. Sutures can be used to ligate or tie off blood vessels, close small bleeders, or secure haemostatic agents in place. The objective of this paper is to explore and develop fundamental procedural suturing skills for non-medical students preparing to undertake aseptic survival surgery in rodent models. This can assist researchers and students in acquiring basic surgical suture skills.
Straightforward Pentafluorosulfanylation for Molecular Design
Authors: Gatzenmeier Tim , Liu Yue , Akamatsu Misato , Okazoe Takashi , Nozaki Kyoko
Published: April 2023

Pentafluorosulfanylation is a powerful boost of molecular properties for many applications. In order to leverage its full potential, a direct and high-yielding synthetic strategy is in great demand. We report here how the discovery of a direct pentafluorosulfanylation of thiolated arenes led to a generalized synthetic approach toward aryl– and heteroaryl pentafluorosulfanyl (SF5) compounds from various common building blocks. The combination of onium halides with silver(II) fluoride (AgF2) provided drastically enhanced oxidative fluorination conditions that enabled the single-step conversion of various thiophenol derivatives to SF5-compounds in high yields and broad scope. The particularly high reaction rate is accounted to an onium fluoroargentate(II)-mediated fluorination mechanism. The recycling potential of inorganic silver byproducts furthermore offers an avenue into industrial-scale production.
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs
Authors: Steinebach Christian , Sosič Izidor , Bricelj Aleša , Murgai Arunima , Bischof Luca , Ng Yuen Lam Dora , Heim Christopher , Maiwald Samuel , Proj Matic , Voget Rabea , Feller Felix , Košmrlj Janez , Schmidt Annika , Lemnitzer Patricia , Hansen Finn K. , Gütschow Michael , Krönke Jan , Hartmann Marcus D.
Published: April 2023

Immunomodulatory imide drugs (IMiDs) such as thalidomide, pomalidomide, and lenalidomide represent the most typical cereblon (CRBN) recruiters that are frequently utilized in proteolysis-targeting chimera (PROTAC) design. These CRBN binders, however, cause degradation of IMiD neosubstrates and are innately unstable as they undergo hydrolytic degradation under mild conditions. Here we present the systematic approach towards novel non-phthalimide CRBN binders that were obtained via the simultaneous optimization of their physiochemical properties, stability, on-target affinity, and off-target neosubstrate modulation features. Our efforts led to the discovery of conformationally-locked benzamide-type derivatives that mimic the interactions of the natural CRBN degron, displayed improved chemical stability, and showed a favorable selectivity profile with respect to the recruitment of neosubstrates. The usefulness of the most potent ligands was demonstrated by their conversion into potent degraders of BRD4 and HDAC6 that displayed superiority compared to previously described benchmark PROTACs. We show that our diversified CRBN ligands offer opportunities to design chemically inert proximity-inducing compounds with reduced neomorphic E3 ligase activity of CRBN.
High level of infection prevention and control in surveyed hospitals in Colombia, 2021
Authors: Corredor Sandra Milena , Abrahamyan Arpine , Thekkur Pruthu , Reyes Jorge , Celis Yamile , Cuellar Claudia , Zachariah Rony
Published: April 2023

Objective.

This study aimed to determine the performance of infection prevention and control (IPC) programs in eight core components in level 2 and level 3 hospitals across all provinces in Colombia.

Methods.

This cross-sectional study used self-assessed IPC performance data voluntarily reported by hospitals to the Ministry of Health and Social Protection during 2021. Each of the eight core components of the World Health Organization’s checklist in the Infection Prevention and Control Assessment Framework contributes a maximum score of 100, and the overall IPC performance score is the sum of these component scores. IPC performance is graded according to the overall score as inadequate (0–200), basic (201–400), intermediate (401–600) or advanced (601–800).

Results.

Of the 441 level 2 and level 3 hospitals, 267 (61%) reported their IPC performance. The median (interquartile range [IQR]) overall IPC score was 672 (IQR: 578–715). Of the 267 hospitals reporting, 187 (70%) achieved an advanced level of IPC. The median overall IPC score was significantly higher in private hospitals (690, IQR: 598–725) than in public hospitals (629, IQR: 538–683) (P < 0.001). Among the core components, scores were highest for the category assessing IPC guidelines (median score: 97.5) and lowest for the category assessing workload, staffing and bed occupancy (median score: 70). Median overall IPC scores varied across the provinces (P < 0.001).

Conclusions.

This countrywide assessment showed that 70% of surveyed hospitals achieved a self-reported advanced level of IPC performance, which reflects progress in building health system resilience. Since only 61% of eligible hospitals participated, an important next step is to ensure the participation of all hospitals in future assessments.
English language teachers' assessment procedure during covid19 pandemic: Challenges and solutions
Authors: Gülşah Öz , Zeynep Çetin Köroğlu
Published: April 2023

The aim of the current research is to investigate the language assessment literacy perceptions of EFL (English as a Foreign Language) teachers working at state primary, middle, and high schools in Turkey. Another purpose of the study was to investigate how EFL teachers adapted their language assessment skills to the online teaching context during the Covid- 19 pandemic, and to what extent. Additionally, challenges and solutions of teachers in transforming their language assessment skills into online education were investigated. A mixed-methods study was employed as the research design. The study obtained and triangulated both qualitative and quantitative data to enhance its validity. In the quantitative phase, Vogt and Tsagari (2014)'s LAL questionnaire which includes three factors i.e. Language Testing and Assessment (LTA), classroom-focused LTA, and purposes of testing, content and concepts of LTA was administered to the participants. The quantitative data were descriptively analysed through the SPSS program in order to identify EFL teachers' training levels and needs in online language assessment. The qualitative data for the study were gathered through written structured interviews with (n) EFL teachers and analyzed using inductive methods. The study's findings revealed that the teachers have a high level of assessment literacy in terms of both face-to-face and online assessment and are familiar with basic assessment tools. However, there is a gap between their theoretical knowledge of assessment and their classroom practices. Additionally, the teachers expressed a need for more in-service training in assessing the skills of English language learners in online environments.
The Structure Again! Common Mistakes in Writing the Discussion
Authors:   Kazan Federal University, Kazan, Russia, Bisimbaeva Dinara
Published: April 2023

One of the most frequent comments that the editors of Education and Self Development make at the stage of preliminary assessment includes the Discussion. This section is either not discursive or written superficially. In this editorial I want to delve deeper into this issue. To begin with the structure of a scholarly paper, we recommend using the IMRaD format. This is an acronym made up of the first letters of the following chapters: introduction, methods, results and discussion. There are variations within this format depending on the scope of a journal. For instance, the introduction can contain the analysis of prior studies, discussion can be integrated into the results chapter or the discursive aspect of a paper can be combined with conclusion. Though this practice is acceptable, we do not recommend authors to use integration. The rationale behind this recommendation is that it is difficult to achieve a balance in case of incorporation. When authors combine the results with the discussion, the focus is often shifted towards the findings, and the discussion usually gets lost in a huge flow of information or is not even presented. Therefore, separate sections eliminate such shortcomings.
И снова структура! Основные заблуждения при написании раздела «Дискуссия»
Authors:   Kazan Federal University, Kazan, Russia, Bisimbaeva Dinara
Published: April 2023

Одно из самых частных замечаний, которые редакция журнала «Образование и саморазвитие» делает авторам на этапе предварительного рассмотрения статей, – это слабо раскрытая дискуссионность результатов исследования. Иногда материал, представленный в разделах «Дискуссия» или «Обсуждение», вообще не является дискуссионным. В этой редакторской статье я покажу, как избежать ошибок такого типа. Если рассматривать общую структуру статьи, для эмпирических работ мы рекомендуем использовать общепринятую рамку IMRaD. Это английская аббревиатура, которая состоит из названий основных разделов рукописи: введение, методология, результаты и дискуссия. В рамках этой структуры возможны варианты в зависимости от специфики журнала. Например, введение может содержать анализ исследованности проблемы, результаты могут быть интегрированы с дискуссией или дискуссия может быть объединена с заключением. Несмотря на то что подобная практика допустима, мы не советуем нашим авторам прибегать к интеграции. Это объясняется тем, что при объединении довольно сложно выдержать баланс и не сместить фокус в ту или иную сторону. Когда авторы соединяют результаты с дискуссией, чаще всего центр описания смещается в сторону результатов, а обсуждение или совсем не представлено, или размыто в большом потоке авторских данных. Дискуссия в виде отдельной рубрики исключает недостатки подобного рода.
Investigating the Effect of Synchronous and Asynchronous Computer-Mediated Peer Feedback on IELTS Candidates’ Writing Development and Interactions
Authors:   Islamic Azad University, Isfahan, Iran, Boyer Hassani Javad , Chalak Azizeh ,   Islamic Azad University, Isfahan, Iran, Heidari Tabrizi Hossein ,   Islamic Azad University, Isfahan, Iran
Published: April 2023

The present study investigated the effect of synchronous and asynchronous computer-mediated peer feedback on IELTS candidates’ writing improvement and interactions. In so doing, 132 IELTS candidates from an English language center in six writing classes were chosen based on the convenience sampling procedure. They were split into three equal groups: two experimental groups that were instructed through synchronous peer feedback and asynchronous computer-mediated feedback and one control group. The data were collected using a sample English language proficiency test and synchronous and asynchronous media writing scoring rubric. One-way ANOVA and Chi-square test were applied for the statistical analysis of the data. It was revealed that L2 learners benefited more from the computer-mediated peer feedback than conventional paper and pencil peer feedback. Further, the participants in the asynchronous group noticeably exceeded the IELTS candidates in the synchronous group. The results also showed that the most frequent feedback in both experimental groups was directive feedback. However, there were some discrepancies in the frequency of various directive subcategories. Suggestion was the most frequent directive subcategory reported by the synchronous group and instruction feedback was the most repeated one in the asynchronous group. On the basis of the findings of the study, instructors were advised to employ asynchronous feedback whenever possible to maximize their learners’ writing accuracy.
Post-graduate Training in the Competence Development of CLIL Teachers
Authors:   Universitat Politècnica de València – Technical University of Valencia, Valencia, Spain, Polyakova Oksana , O’Callaghan Shona ,   Catholic University of Valencia, Valencia, Spain
Published: April 2023

Content and Language Integrated Learning (CLIL) approach has become one of the bilingual education pillars worldwide. Its application often relies on quality instruction; therefore, careful preparation of future CLIL educators will guarantee adequate CLIL implementation. Despite the extensive research on the method used since the 1990s, little is known about the competence-based training process of content and language teachers. Through a multi-dimensional perspective of the current research, including qualitative and quantitative methods, the study authors attempt to demonstrate that CLIL competences can be adequately developed. In our project, we taught a postgraduate course on Delivering the curriculum through English to 26 educators and analysed the development of their professional skills. Pilot study results show that competence development is highly correlated with linguistic awareness, in-depth theoretical and applied knowledge of the CLIL approach and mutual support within teaching community. Regardless of the fundamental idea of formative exploration, our study presents some findings deserving of thought by teacher trainers and policymakers currently applying CLIL methodology.
The Philosophical Literary Story as a Model of Critical Thinking
Authors:   Constantine the Philosopher University in Nitra, Nitra, Slovakia, Borisova Simona , Pintes Gabor ,   Constantine the Philosopher University in Nitra, Nitra, Slovakia
Published: April 2023

This article focuses on a detailed review of philosophical literary stories which represent specific area of the Philosophy for children programme primarily aimed at independent thinking development in education process. The benefits of the programme are characterised within the theoretical basis on the level of critical, creative and caring thinking. The philosophical literary story is a part of fiction. It covers philosophical categories, but it is characterised with simplicity in its theme, as well as content and language part. The role of this type of text lies mainly in motivation toward consequent philosophical discussion in a group called community of inquiry. Through the literary text interpretation method, we demonstrate presence and interconnection among critical thinking categories. At the same time, we discuss the subject type of texts as a specific model for critical thinking level development.
Mechanisms for Optimizing and Updating the Content and Methodological Training of Future Primary School Teachers
Authors:   Kazan Federal University, Kazan, Russia, Vlasova Vera , Zakirova Venera ,   Kazan Federal University, Kazan, Russia, Kamalova Lera ,   Kazan Federal University, Kazan, Russia, Kayumova Leysan ,   Kazan Federal University, Kazan, Russia, Sabirova Elvira ,   Kazan Federal University, Kazan, Russia, Khairova Irina ,   Kazan Federal University, Kazan, Russia
Published: April 2023

The article presents a structural practice-oriented model of preparing a future teacher for an active professional activity, taking into account the educational standards of primary general education, based on practical forms of educational activity, provided with a high level of theoretical knowledge and possession of the methodology and technologies of self-knowledge. The model embodies the original scientific and methodological support for the process of professional training of future teachers at Kazan University, the system priority of which was the realization of the student's personal capabilities through interactive methods of his cognitive, communicative and axiological activities. Scientific and methodological support is considered as an applied empirical mechanism for optimizing and updating the content and methodological training of future teachers who are capable of creative organization of the process of teaching younger students, of effective adjustment and development of basic educational programs in elementary school. The information-logistical approach has become the leading one in the study of the problem, which is important in conditions when the content of education is shifting from memorization to the search, selection and comprehension of information, and teacher training is carried out in an environment that provides an integrated perception of experience, allowing him to be included in the advanced design of the content of education. The article describes a system of interrelated practice-oriented activities, determined by the dynamics of content modules, the conditions for their implementation and evaluation criteria, aimed at developing the professional competencies of future teachers, improving their qualifications and professional skills in obtaining personal, meta-subject and subject results. The original scientific and methodological support for the process of professional training of future teachers offers interactive methods that represent innovative and unique tools for designing the learning process and predicting its effectiveness, allowing you to most accurately determine the advantages and problems of the real educational process of teacher training when testing new technologies and teaching methods. The implementation of the proposed scientific and methodological support expands and actualizes the resource content of the educational process through empirical research based on the study, analysis and generalization of real innovative pedagogical experience.
The Role Structure of the Professional Activity of a Higher School Teacher in the Context of Digitalization of the Educational Environment
Authors:   Siberian Transport University, Novosibirsk, Russia, Gileva Kristina
Published: April 2023

In the context of changing the paradigm of vocational training, teachers of higher education are faced with new requirements related to changes in the content of the pedagogical process and new functions that teachers need to master in the context of the introduction of systemic and integrated learning technologies. The elements of the educational environment form a whole range of new forms of activities that a modern teacher must implement in the educational process. The current conditions determine the emergence of contradictions, the resolution of which requires the study of a new role structure of professional pedagogical activity. The purpose of the publication is to present the results of a study of the role structure of pedagogical activity in higher education, to identify areas of gaps in the expectations and assessments of the existing role structure of teachers on the part of students and in the assessments of the teachers themselves. The sample of respondents-teachers consisted of more than 70 people, as well as more than 200 people - students of various areas of training at universities in Novosibirsk. The methodological basis of the study is the principles of the subject-subject approach in pedagogy, a number of developments of domestic researchers dedicated to the formation and development of open education in the Russian Federation, as well as the evolution of the teacher's role set in connection with changes in the pedagogical paradigm of higher education). In the process of collecting empirical material, the author's standardized questionnaire was used to identify the types of roles of a modern teacher. As a result of the study, the predominant types of roles in the professional activities of teachers of higher education were identified, a comparison was made in the areas of training, gaps were identified in relation to the existing role structure in the views of teachers and students, as well as between the expectations that students have and those roles that today demonstrated by teachers in the learning process. The novelty of the study lies in the empirical substantiation of the role model of a higher education teacher, determining the most relevant roles and identifying those problem areas that require systematic and targeted work on self-development and professional development of higher education teachers.
Assessment of the Quality of Norm-Setting in the Educational System in a Modern School
Authors:   The Middle Volga Institute (branch) of the All-Russian State University of Justice (RLA of the  Ministry of Justice of Russia), Saransk, Russia, Koval Ekaterina ,   National Research Mordovia State University, Saransk, Russia, Sychev Andrey ,   National Research Mordovia State University, Saransk, Russia,   Industrial University of Tyumen, Tyumen, Russia, Zhadunova Nataliya ,   National Research Mordovia State University, Saransk, Russia
Published: April 2023

The results of the educational process often cause criticism from the state, parental and pedagogical communities and society as a whole. This is due to the fact that norms created at the institutional level of the education system do not always allow achieving goals at the procedural level. It is the school teacher, as a key subject of educational activity, who is able to give the most reasonable answer to the question if the existing norms really help to achieve educational goals. In this regard, the purpose of the study is to assess the quality of norms and norm-setting in the field of education and to determine the possibilities and prospects for the deliberate participation of the pedagogical community in it. An expert survey of practicing teachers (N = 87) was conducted with the help of Google Forms service. Respondents evaluated the norms of the Constitution of the Russian Federation; federal laws; codes of pedagogical ethics, etc. The experts' assessment of the norms showed that normative regulation of the sphere of education set the important priorities in upbringing. However, there are problems associated with the implementation of these priorities due to excessive bureaucratization; limitation of the creative potential of teachers; unwillingness to constructively interact with other subjects of norm-setting, etc. The majority of teachers cannot influence the creation, change or abolition of norms that regulate the educational process at school (with the exception of the local norms). But they are ready to actively participate in the public discussion of the norms regulating upbringing. The research results can be used to further study of the education system through the prism of norm-setting activity, and can also be useful for the formation and implementation of mechanisms for the participation of the pedagogical community in determining the value-normative priorities of upbringing.
Professional Competencies of Specialists in Economic Security Degree Programme
Authors:   Orenburg State University, Orenburg, Russia, Pankova Svetlana , Koske Margarita ,   Plekhanov Russian University of Economics, Orenburg Branch, Orenburg, Russia, Voyutskaya Inna ,   Plekhanov Russian University of Economics, Orenburg Branch, Orenburg, Russia, Mishuchkova Yuliya ,   Orenburg State University, Orenburg, Russia
Published: April 2023

The problem of the formation of professional competencies of specialists in economic secu-rity is caused not only by new technologies, but also by the transformation of existing spheres of professional activity. Russian universities provide training economists in the field of Economic Security in the lack of a corresponding professional standards set offi-cially approved by the Ministry of Labor of the Russian Federation. Thus it updates the search for evidence-based practices that allow formation of majors' professional competen-cies based on corresponding job functions, occupational profile and adequately responding to the labor market demand. To solve it, a theoretical justification is given and an algorithm for the formation of professional competencies. The aim of the study - is to justify the link between theory and practice for implementing a competency-based approach to training economic security professionals by developing an algorithm formation of professional competencies in unity with the sequence of determin-ing indicators of their achievement based on the consistency of the provisions with the re-quirements of the labor market. The methodology and methods of the study are based on the application of the following general scientific and special research technique: gathering of empirical data, comparison, abstraction, specification, analogy. Research results provides a short summary of recommendations for ensuring the effective-ness of the indicators of professional competencies formation during university tenure based on the experiential learning and theory opportunities for students in the field of eco-nomic security to apply the needed knowledge and skills set they gain. A model has been developed for the formation of professional competencies of an economic security specialist, which provides universities with tools to determine the necessary knowledge, skills and abilities in the field of professional activity, which can be diagnosed using appropriate indicators.
Corporoplasty with synthetic graft in fibroplastic penile induration.
Authors:   urology center of the «Medassist» medical center, Panferov A.S. ,   Kursk, Russia, Bekreev E.A. ,   urological department of the urology center of the «Medassist» medical center; Kursk, Russia, Elagin V.V. ,   Center of Urology of the «Medassist» medical center; Kursk, Russia, Kotov S.V. ,   Department of Urology and Andrology of the Medical, Faculty of the N.I. Pirogov Moscow State Medical University of the Russian Ministry of Health; Moscow, Russia
Published: April 2023

Introduction. Peyronie's disease is a multifactorial disease leading to various types of penile deformities. Surgical treatment is the most effective method of correcting erectile deviation. In patients with preserved erectile function the technique of plaque incident with grafting is widely used, in the presence of erectile dysfunction phalloprosthesis with plaque incident and grafting should be performed. The question of the choice of material for defect replacement in surgical treatment of Peyronie's disease is relevant, because today none of the used grafts is a reference. Aim of the study. Evaluation of the results of corporoplasty using synthetic grafts in patients with Peyronie's disease. Materials and methods. 11 patients underwent corporoplasty using a synthetic graft made of modified polytetrafluoroethylene (ePTFE), in 4 cases this technique was combined with falloprosthetics. Results. Erectile deviation was eliminated in all patients. At the same time, no early and long-term complications were noted during the follow-up. All patients were satisfied with the outcome of the surgical intervention. Conclusion. Synthetic grafts can be used for surgical treatment of Peyronie's disease with the achievement of a positive effect. The use of this material in the treatment of Peyronie's disease requires further study.
Male preconceptional training: the role of nutrition and nutrient complexes. Part 1.
Authors:   clinic «Men’s health», professor of the Department of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, a leading researcher of FSBUI Kulakov National Research Center of Obstetrics, Gynecology and Perinatology, Bozhedomov V.A. ,   Moscow, Russia, Kononenko I.A. ,   Clinic of Aesthetic Medicine «Galaxy»; Saint-Petersburg; Russia
Published: April 2023

Introduction. One of the reasons for the decline in the reproductive function of men is an unbalanced diet. This review is devoted to the assessment of the role of such nutrients as vitamin E, L-carnitine, coenzyme Q10, zinc, selenium and arginine in the occurrence of male infertility: their role in spermatogenesis and the possibility of clinical application are shown. Materials and methods. Publications from domestic and international databases (Russian State Library, MEDLINE, PubMed, Cochrane Database of Systematic Reviews) were analyzed: original studies, relevant chapters in collective monographs available to the authors, reviews, incl. Cochrane, meta-analyses over the last 20 years. When searching in electronic databases, the following keywords were used: male infertility, food products, oxidative stress, male infertility therapy, nutrients, incl. the name of individual substances: carnitines, ubiquinone/coenzyme Q10, selenium, zinc, vitamin E, arginine in various combinations. Results. From the standpoint of fundamental sciences (physiology and biochemistry) and, at the same time, data from clinical medicine, the role of various nutrients in the implementation of male reproductive function, as well as their use for preconception preparation of men, is considered. A quantitative assessment of the effectiveness of isolated and complex use of these nutrients to increase the concentration and mobility, improve morphology, reduce oxidative stress and DNA damage in spermatozoa is given. Conclusion. Nutrients play an important role in metabolic processes during the formation and maturation of spermatozoa. Their deficiency leads to impaired reproductive function, and additional intake in the form of dietary supplements can lead to an increase in the likelihood of pregnancy and live births due to improved motility, concentration and fragmentation of sperm DNA. At the same time, today it is difficult to give any clear recommendations for their use as a therapy in infertile men. A significant number of studies lack randomized and placebo-controlled groups. Randomized controlled trials of sufficient power, taking into account the deficiency of individual nutrients, should be planned to clarify the indications for the use of specific dietary supplements in the concept training of men.
Predictors of success performing ureterolitotripsy.
Authors:   urology department Central State Medical Academy of Department of presidential affairs, Moscow, Russia, Darenkov S.P. , Pronkin E.A. ,   Central State Medical Academy of Department of presidential affairs, head of urology Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency; Moscow, Russia, Monastyrnyy G.A. ,   urology Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency; Moscow, Russia, Novikov V.A. ,   Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia
Published: April 2023

Urolithiasis is one of the most common diseases seen by urologists. In 28% of patients with kidney stones, the disease is symptomatic. The benefits of ureteral stone extraction include minimal invasiveness, a shorter postoperative recovery time, and a favourable safety profile. Aim: to compare and evaluate the relationship between the density of the ureter, the density of the calculus, its localization and the value of the creatinine level and predicting the success of ureterolithoextraction. Materials and methods. In total, 125 ureteral lithotripsy procedures were performed (42 in women and 83 in men). Initially, the patients were divided into two groups. In the first group, ureteral stone extraction was performed in 97 patients. The second group included 28 patients with ureteral stent placement, without ureteral lithotripsy. In percentage terms, the increase in mean calculus size in the groups (10%) was less significant than the increase in ureter density under the calculus (65%). Results. There was no relationship between the ureter density under the calculus and the residence time of the calculus in the ureter. However, there is a relationship between the residence time of the calculus and the anatomical narrowing of the ureter, which may affect the success of the procedure. Elevated creatinine levels in the group with initial ureteral stent placement may indicate impaired urine passage from the kidney. Conclusions. Routine measurement of the ureter density under the calculus during MSCT may be an additional parameter in determining the surgical treatment method.
Prevalencia de hipogammaglobulinemia persistente en pacientes con enfermedad autoinmune que reciben rituximab en un centro de referencia nacional en México
Authors: Fraga Olvera Alira , Saavedra-Salinas Miguel Angel , Beltrán Mendoza Jesus Quetzalcoatl , Mendieta Flores Elizabeth
Published: April 2023

Objetivo: Determinar la prevalencia de hipogammaglobulinemia persistente en pacientes con enfermedades reumatológicas autoinmunes que reciben rituximab.
Métodos: Estudio trasversal, retrospectivo y unicéntrico, emprendido en pacientes con enfermedades reumatológicas autoinmunes, que acudieron a la Consulta externa del servicio de Reumatología del Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, Ciudad de México, entre enero de 2013 y enero de 2018, para recibir tratamiento con rituximab. El análisis de los datos se efectuó con estadística descriptiva e inferencial, para la evaluación de las concentraciones séricas de inmunoglobulinas, características clínico demográficas, diagnóstico y tratamiento.
Resultados: Se registraron 262 pacientes con enfermedad reumatológica autoinmune que recibieron rituximab. Se identificaron 8 (6 mujeres y 2 hombres) casos con hipogammaglobulinemia persistente, con una prevalencia del 3.1% de la población total. No se identificaron factores asociados con hipogammaglobulinemia.
Conclusiones: Hasta el momento no se han identificado factores asociados, pronósticos o predictivos, con hipogammaglobulinemia persistente. Se requieren estudios prospectivos adicionales para conocer con mayor precisión las implicaciones de la hipogammaglobulinemia persistente en pacientes con enfermedades autoinmunes.
O PAPEL DA VIVÊNCIA NA PESQUISA COM FORMAÇÃO DE PROFESSORES FORMADORES DE PROFESSORES: REFLEXÕES INICIAIS
Authors: FERREIRA Isabel Cristina Fernandes , BISSOLI Michelle de Freitas , LUNA Rita Esther Ferreira de
Published: April 2023

Este artigo apresenta reflexões preliminares sobre o papel da vivência na pesquisa com formação, desencadeadas por pesquisas de Doutorado em Educação cujo objeto de estudo foi a formação de professores formadores de professores para/da Educação Infantil. Tem suas bases nos pressupostos da Teoria Histórico-Cultural, funde-se com as reflexões realizadas ao longo dos processos investigativos e das discussões no grupo de pesquisa, cujos materiais e dados foram selecionados, sistematizados e analisados. Acreditamos que as vivências podem assumir papel fundamental na constituição de pesquisas engendradas com o processo formativo e que com ele se estruturem, fortaleçam e se ampliem.
INFLUENCE OF COVID-19 ON BREAST CANCER DIAGNOSIS AND FOLLOW-UP IN BRAZIL
Authors: Ramos Maria Fernanda Passos Rocha , Ramos Dandara Rocha , Ramos Paulus Fabricio Mascarenhas , Avena Katia de Miranda , Sousa Isabela Gonçalvez de Araújo
Published: April 2023

Objective: The aim of this study was to verify the impact of the COVID-19 pandemic on the expected number of breast cancer diagnoses in Brazil. Methods: This is an observational, cross-sectional, analytical study conducted using secondary data collected from the Cancer Information System (SISCAN/DATASUS), analyzing two time slices (2020–2021 and 2021–2022). Women diagnosed with breast cancer who underwent mammography between 2020 and 2022 were included in the study. Research Ethics Committee review was waived because aggregated public data were used without identifying participants. Results: In the data collection conducted in 2021, it was possible to see underdiagnoses of breast cancer in the year 2020, when only 22,167 new cases were reported, when about 66,280 cases were expected. However, in 2022, with the update of the data in SISCAN/DATASUS, it was observed that in addition to underdiagnoses, there was a scenario of underreporting, since in 2022, the number of diagnoses was about 47,557 new cases of breast cancer in 2020 in Brazil. This scenario reflects the epidemiological health overload resulting from the pandemic, resulting in neglected attention to other diseases of high incidences, such as breast cancer. Conclusion: During the COVID-19 pandemic, a significant underreporting of breast cancer diagnoses was observed in Brazil, affecting epidemiological monitoring. It is believed that this scenario will reflect not only on the increase in severe cases of breast cancer but also on public health expenses.
OVERVIEW OF MAMMOGRAPHY IN GOIÁS BETWEEN 2016 AND 2021
Authors: Silva Kallyta Myllena e , Silva Micaellem Rodrigues Santos da , Costa Wanessa Rocha , Soares Leonardo Ribeiro
Published: April 2023

Objective: This study described the clinical-epidemiological characteristics of women undergoing mammography in the State of Goiás from 2016 to 2021. Methods: This is a cross-sectional, ecological study of women who underwent mammography between 2016 and 2021 in the state of Goiás. The DATASUS database of the Cancer Information System (SISCAN) was used, where age group, municipality of residence, and clinical indication were applied for analysis. Results: Between 2016 and 2021, in Goiás, 451,589 mammograms were performed on women aged 9 to over 79 years, with an average of 75,265 mammograms per year. In 2019, 89,868 procedures were performed, which was the highest number recorded in the analyzed period. In contrast, 2020 had lower demand, totaling 50,263 mammograms. As for the clinical indication, of the 365,152 requested mammograms, 354,370 aimed at screening, mainly for the high-risk population that includes women with a family history of breast cancer, representing 8,617 examinations. In addition, 13,853 mammograms had a diagnostic objective based on suspicious clinical findings, and 5,432 patients underwent mammography for previous treatment of breast cancer. The age group that most underwent mammograms was 50–54 years, totaling 17.3% of the total. In Goiânia, the rate of mammography performed, from 10 to 79 years old, was 4.8% and São João da Paraúna registered the highest rate with 20.5%. Goiânia, Aparecida de Goiás, and Anápolis lead the ranking of mammograms performed, representing 53% of the procedures performed in the state. Conclusion: Through the analysis, it is possible to infer that there is a disproportionate distribution of health resources in the territory of Goiás. In addition, the reduction in the number of mammograms in 2020 is correlated with the COVID-19 pandemic, allowing the loss of early diagnoses in many women, thus contributing to an unfavorable prognosis in the future.