bluuebunny/crossref_metadata_2025 huggingface dataset:
A ANTÍGONE DE SÓFOCLES NA TRANSCRIÇÃO MUSICAL DE GUILHERME DE ALMEIDA
Authors: Guimarães Sandra Regina
Published: February 2025

Este artigo é parte de uma pesquisa de pós-doutorado, em andamento, na qual, partindo do manuscrito original da tradução/transcrição da Antígone de Sófocles, feita por Guilherme de Almeida – ao qual tivemos acesso por meio do Fundo Guilherme de Almeida, do IEL UNICAMP – desejamos empreender um estudo crítico-genético da tradução de Almeida, verificando, em que medida, a inserção do “Príncipe dos Poetas Brasileiros” no movimento modernista, bem como a musicalidade inerente à sua composição poética irão impactar a sua “transcrição” de Antígone de Sófocles. Fará parte ainda da nossa pesquisa, a análise da recepção da tradução do texto de Guilherme de Almeida no século XX e seu impacto sobre as traduções subsequentes. Desejamos, por fim, demonstrar a universalidade da temática sofocliana, em Antígone, bem como a importância da sua composição, na construção de uma literatura genuinamente brasileira.
Reorganización simplificada para micro y pequeñas empresas y necesidad de su profundización
Authors: Calahorrano Latorre Edison Ramiro
Published: February 2025

Resumen: el presente trabajo analiza, el procedimiento de reorganización simplificada para micro y pequeñas empresas introducido por la Ley 21.563 a la Ley 20.720 de reorganización y liquidación de empresas y personas en Chile. Para lograr el objetivo señalado se indagó respecto de la efectividad de procedimiento de reorganización judicial y verificó si la versión simplificada de este mecanismo cumple con las recomendaciones de la Guía Legislativa de CNUDMI y principios que fomenten la reorganización de aquellas empresas viables o principio de segunda oportunidad; así como, un marco normativo favorable a las micro y pequeñas empresas, enfocando el análisis en la participación de los veedores, características de período de protección financiera concursal . Se contrasta el contenido de la reforma en estos tres puntos con lo regulado en la Ley de Concurso Preventivo en Ecuador y lo que contenía el proyecto de Decreto Ley de Reestructuración Empresarial de dicho país. La hipótesis planteada es que hay un cumplimiento parcial de lo señalado, por lo que los cambios no profundizan en la reducción de complejidad respecto de proceso ya presente en la Ley requiriendo una profundización en los instrumentos disponibles para el small business.
BREVE ESTUDO SOBRE A ESTRUTURA DE GOVERNANÇA ACADÊMICA E ADMINISTRATIVA DO SISTEMA UAB E A MANUTENÇÃO DA QUALIDADE DOS CURSOS
Authors: Lira Luiz Lira , Domingo Reinaldo Portal
Published: February 2025

Este relato de experiência tem como objetivo apresentar considerações acerca da importânciaassumida pela política pública instituída por meio do Sistema Universidade Aberta do Brasil (UAB)em relação à estratégia descentralizada de sua atuação por meio dos cursos ofertados pelasinstituições que integram a sua estrutura. A UAB possui atualmente 147 instituições públicas, umtotal de 970 polos integrados e 685 cursos ativos em 5.555 turmas (Sisuab, 2024), e se constitui,como um sistema formado por universidades públicas que oferecem cursos de nível superior paracamadas da população que têm dificuldade de acesso à educação universitária. Este modelo sealinha às políticas de equidade e democratização do acesso ao ensino superior e à necessidadede flexibilização da oferta educacional no país. Ressalte-se que, desde a publicação do decreto5.800/2006, experiências acumuladas pela UAB voltadas ao trabalho sistemático de elevação daqualidade dos cursos, a partir dos aperfeiçoamentos constantes dos processos de gestão, tantoacadêmicos como administrativos, solidificaram a presença do(a) discente no centro do processode formação, possibilitando a elevação do nível científico-tecnológico do corpo social em todas asinstituições participantes. O relato vai apresentar ainda como ocorrem os processos seletivos dosprincipais atores (docentes, tutores e pessoal de apoio), no sentido de mostrar a transparência, apublicidade e a sustentabilidade dos atos da gestão acadêmica e administrativa.
Palavras-chave: Universidade Aberta do Brasil, Qualidade da Formação, Gestão Acadêmica eAdministrativa, Transparência.
ОБРАЗЫ КИНОКЕФАЛОВ В ИКОНОГРАФИИ КАК ОТРАЖЕНИЕ ПАРАДОКСАЛЬНОСТИ ЧЕЛОВЕЧЕСКОЙ ПРИРОДЫ В МЕНТАЛЬНОЙ КУЛЬТУРЕ СРЕДНЕВЕКОВЬЯ
Authors: Дьяченко Ольга Николаевна , Королёва Людмила Георгиевна
Published: February 2025

Цель исследования состоит в экспликации ключевых идей в понимании человеческой природы в Средние века, запечатленных в сюжете и знаково-символических компонентах образа кинокефалов, выявлении связи метафизических смыслов, которые были в основании ментальной традиции этой эпохи, средств и способов их выражения в иконописном искусстве.
Методологическую базу исследования составил комплексный подход, заданный междисциплинарным характером предмета рассмотрения. Определение специфики представлений о человеческой природе в русле средневекового теоцентризма потребовало обращения к методу контекстуального анализа. Диалектический метод использовался при выявлении способов передачи фундаментальных для культуры Средних веков религиозно-философских идей в знаково-символическую структуру и сюжет иконографических изображений на примере образа святого Христофора.
Результаты исследований. Исследована история возникновения, специфика сюжета и знаково-символическая структура икон святого Христофора как источника понимания метафизических и бытийный смыслов в природе человека, что является отражением фундаментальных для культуры Средних веков ментальных идей, представленных в иконографических образцах. В результате установлено, что зооморфные образы и детали иконографии, которые были проанализированы на примере образов киноцефалов, не следует рассматривать лишь как прямое заимствование из культур, существовавших в дохристианские времена. Установлено, они являются рецепцией библейских идей, представленных в работах философов патристики, а иконографические образы необходимо исследовать с позиции фундаментальных метафизических оснований, которые задают интенциональность ментальной культуре, получившей свое органичное продолжение в искусстве.
Перспективы исследования заключаются в необходимости концептуализации феномена ментальной культуры Средневековья, которая предполагает расширение возможных подходов в исследовании иконографии как выражение и продолжение текстовой культуры этой эпохи.
ВИЗУАЛИЗАЦИЯ СОЦИАЛЬНО-ГУМАНИТАРНЫХ ЗНАНИЙ КАК СПОСОБ ИХ ПРЕДСТАВЛЕНИЯ: ПОДСТУПЫ К ПРОБЛЕМЕ
Authors: Кошлаков Дмитрий Михайлович
Published: February 2025

Целью исследования является рассмотрение различных способов представления действительности, применяемых в современном научном знании, и выявление в ряду этих способов места, отводимого визуализации вообще и визуализации знаний в частности.
Методологическую основу исследования составляют положения различных вариантов современного эпистемологического знания: социальной эпистемологии, исторической эпистемологии и визуальной эпистемологии.
Результаты исследования. В современном научном знании используется несколько способов представления знаний: формально-аналитический, визуальный (графический), табличный, текстовый (текстологический) и образный. При этом указанные способы являются некоторыми типами (но не видами) представления действительности, то есть границы между ними не являются строго определенными, а сами способы в реальной научной практике довольно часто совмещаются, то есть, по большому счету, наслаиваются друг на друга. Применительно к визуальному способу представления действительности принято различать три типа визуализации: визуализация данных, визуализация информации, визуализация знаний. В рамках современного социально-гуманитарного знания наибольший интерес в настоящее время представляет визуализация знаний, что обусловлено широким применением других типов визуализации в научном знании, а также ограниченностью их возможностей в социально-гуманитарном знании и некоторой спецификой и абстрактностью данного типа знания.
Перспективу исследования составляет построение теории визуального моделирования с целью применения данного типа моделирования в практике социально-гуманитарного познания.
ГУМАНИЗМ И ВОЙНА: ВОЗМОЖНА ЛИ ГУМАННАЯ ВОЙНА ИЛИ ВОЕННЫЙ ГУМАНИЗМ?
Authors: Рудкевич Елена Юрьевна
Published: February 2025

Цель исследования заключается в анализе таких понятий, как «война» и «гуманизм» и оценке возможности их синтеза.
Методология исследования определена самой темой и целью. Используются методы анализа, сравнения и сопоставления.
Результаты исследования. Философский анализ понятия гуманизма имеет давнюю историю. Зародившись на заре эпохи Возрождения, гуманизм как вполне определенная ценностная категория претерпевает существенные трансформации. Современность рождает иное понятие — трансгуманизма, продукт прогрессизма, эволюционизма, техницизма. Наполненность современного общества военными конфликтами противоречит всем известным канонам гуманизма, однако появляются попытки примирить такие понятия, как «гуманизм» и «война», в результате чего появляются понятия военного гуманизма, гуманной войны и т. д. Теоретической основой исследования служат работы Аристотеля, И. В. Гете, Г. Ф. В. Гегеля, Г. Ф. Николаи, Н. Хомского. В работе показана совместимость понятий гуманизма и войны. Выявлено, что в современном обществе ценности абстрактного гуманизма не работают, а выходящий на передний план трансгуманизм наиболее точно отвечает реалиям современности, заполненной военными конфликтами различной интенсивности.
Перспективы исследования. Обобщения и выводы, содержащиеся в статье, ориентируют на дальнейшее углубленное изучение и анализ работ по соответствующей тематике, а также на тщательное рассмотрение конфликтных ситуаций, военных действий с позиции социально-политического и социально-философского анализа. Кроме того, меняющиеся социальные реалии вносят значительные коррективы в известный смысл понятия гуманизма, что требует дополнительного осознания и объяснения.
МЕЖЭТНИЧЕСКИЕ ОТНОШЕНИЯ В РЕСПУБЛИКЕ КРЫМ: ЦЕННОСТНО-ИНТЕГРАТИВНЫЙ КОНТЕКСТ
Authors: Узунов Владимир Владимирович
Published: February 2025

Цель исследования. Автором доказывается актуальность исследования проблемы межэтнических отношений, пространства ценностей и идентичностей жителей Крыма. Обосновывается, что для решения поставленных задач целесообразно изучить мнения крымчан относительно уверенности в правильности геополитического выбора в 2014 году, степени социальной напряженности в регионе и влияющих на это факторов, а также степени актуальности проблем межэтнического характера в республике и угроз возрастания потенциала их деструктивности.
Методология. Эмпирической основой исследования выступают результаты анкетного опроса жителей Крыма (N = 700), проведённого коллективом Крымского филиала Федерального научно-исследовательского социологического центра РАН в марте-апреле 2024 года. Объем общей выборочной совокупности определялся, исходя из статистической погрешности не более 3,78 % при доверительном интервале 95 %. Опрос проводился в муниципальных образованиях Симферополь, Ялта, Алушта, Судак, Армянск, Белогорск, Феодосия, Керчь, Евпатория, Бахчисарай. Метод: онлайн-опрос с помощью индивидуальных компьютеров (смартфонов). Объектом исследования выступили территориально обозначенные группы населения Крыма, целевые группы, определенные по итогам предыдущих исследований Крымского филиала ФНИСЦ РАН. Предмет исследования — социологический анализ межэтнических отношений в Крыму, оценка показателей социальной идентичности, а также ценностного пространства крымчан.
Результаты исследования. Межэтнические отношения в Крыму входят в ряд важных проблем, и в настоящее время в данной сфере обнаруживаются достаточно противоречивые тенденции. С одной стороны, интегративный потенциал крымского социума все еще достаточно велик, и уверенность в правильности выбранного геополитического курса служит фактором, объединяющим большинство населения полуострова. Весьма выраженная региональная идентичность также может служить целям дальнейшей солидаризации крымчан. С другой стороны, участники опроса демонстрируют обеспокоенность рядом социальных проблем, в частности наряду с ростом цен и рисками СВО достаточно четкие контуры обретает и проблема межэтнического взаимодействия, редуцируясь до опасности межнационального противостояния и розни. Можно предположить, что упомянутые социальные угрозы могут возрасти без должного внимания исследователей и оперативной реакции государственных и муниципальных органов власти, а также правоохранителей. В таком случае существует опасность того, что позитивный потенциал ряда факторов развития крымского социума (к примеру, тенденции в формировании региональной идентичности) может приобрести противоположные, деструктивные характеристики, усугубив социальную напряженность.
В заключение делается вывод о том, что в пространстве межэтнического взаимодействия Республики Крым в настоящее время фиксируются противоречивые процессы, прослеживаются тенденции как интеграции, так и дезинтеграции регионального социума.
FoliarphytopathogenicfungiassociatedwiththecultivationofPrunuspersicaL.:Morphologicalandmolecularidentification,andbiologicalcontrolwithTrichodermaasperelloides
Authors: Ceballos-Chávez Ángel , Valenzuela Escoboza Fernando , Ayala Armenta Quintín , López Butista Everardo , Márquez Lujan Héctor , López-Valenzuela Blanca
Published: February 2025

The presence of foliar phytopathogenic fungi causes severe damage to leave and fruits of peach (Prunus persica L.), in producing areas of southern Chihuahua, Mexico, which has caused a decrease in production by 30%. The objective of this work was to identify morphologically and molecularly the foliar phytopathogenic fungi associated with the peach tree crop, evaluating the pathogenicity in one-year-old plants against Trichoderma asperelloides. Leaves with brown and brown lesions were collected from mummified fruits on the plant from 19 commercial peach orchards distributed in three municipalities of regional and national production in the State of Chihuahua, Mexico. Fungal identification of four representative isolates was performed using morphological methods. characterization and phylogenetic analysis based on the internal transcribed spacer region (ITS1 and ITS4) of ribosomal DNA, part of the translation elongation factor 1-alpha (TEF) a second secondary primer for each of the genera for, Collectotrichum ACT-512F and ACT-583R, Fusarium with EF1. For plant confrontations, a concentration of 1x106 conidia was inoculated. mL-1 of pathogens such as T. asperelloides, evaluating leaf diameter and length, height, severity and incidence. It was possible to identify the presence of Fusarium sambucinum, Collectotrichum gleosporoides and Monilinia frutícola, in addition the B-F-M1-A2-ACCH-3 strain of F. Sambucinum obtained the highest values in the inhibition of the response variables and in severity Monilinia frutícola presented 61.23% as the highest value. It is recommended to use strain 3 as a biological control of foliar phytopathogens.
The ‘Externalization’ of the European Union Migration and Asylum Policy: A Case Study of the Italy-Albania Agreement
Authors: Muharremaj Erjon , Cami Giola
Published: February 2025

Migration policy and its derivates—refugee and asylum policy—are increasingly important items on national and international agendas. This article provides a comprehensive legal and policy analysis of externalization policy and migration and asylum frameworks at the European Union (EU and national levels. Using an integrated approach in methodology, the article theoretically examines the insights from contemporary debates in the field and briefly analyzes the most recent developments in Europe, where the new Pact on Migration was approved in May 2024. Conducting a comparative legal analysis, we analyze the Protocol on Strengthening Cooperation in the Field of Migration, signed between the Albanian and Italian governments, juxtaposing its provisions with international and EU asylum and immigration law. Furthermore, analysis is contemplated with the critique of the judgment of the Albanian Constitutional Court on the compatibility of the protocol with the Albanian constitution and legal standards pertaining to international human rights law.
We argue that the agreement is presented as a legal framework to, de jure, strengthen cooperation in the field of migration. However, from the text of the protocol, de facto, the agreement is about placing a certain part of the territory of the Republic of Albania under the exclusive jurisdiction of the Italian Republic, where it can “externalize” its asylum seekers, and deter potential immigrants from travelling toward Italy. It is the latest effort of the EU members to “discharge” asylum seekers onto other, poorer countries as a tool of domestic politics rather than to solve the thorny issue of migration. Conclusions are reached on the developments in EU law and policy on migration and asylum and their impact on relations between EU members and other countries. Finally, we provide recommendations to ensure compliance with human rights standards.
Clean Water in Africa: Guaranteed Good, Common Concern of Humanity, or Market Commodity?
Authors: Degterev Denis
Published: February 2025

In this article, the author examines the main approaches to water management in Africa in the context of realizing the right to clean water and sanitation. The features of both public and private water management, as well as the public-private approach, are shown. The author also presents as well the attempts to find a “third way” through decentralization of the management system based on the theoretical developments of Nobel Prize-winner E. Ostrom, a representative of the Bloomington School. Differences in water management in urbanized areas and in rural areas of African countries are shown. In the latter case, the normative and value attitudes of the local community play an important role, and water is not only an important economic resource, but also has great socio-cultural significance. The experience of Burkina Faso illustrates the key role of the public operator in water supply, which has generally remained despite the structural adjustment programmes of the 1990s. The article presents the main features of the privatization of water management in the countries of the Global South and the expert criticism that has been gaining momentum in this regard. At the mid-2000s, the anti-privatization agenda shifted to the promotion of the human right to clean water. The process of adoption of United Nations General Assembly (UN GA) resolution 64/292 “The human right to water and sanitation” on 28 July, 2010 and the mechanisms for its implementation, including within the framework of the Sustainable Development Goals (SDG 6), as well as the place of water issues in the discussed draft of the International Covenant on the Right to Development are shown. The main stakeholders of the global water governance mechanism within the UN and the World Bank are presented, and the special role of leading water multinational corporations (MNCs) and specialized consulting firms, as well as France, are highlighted. Particular attention is paid to the implementation of the right to water in Africa, including within the framework of the 2019Guiding Principles on the Right to Water in Africa, Agenda 2063, and the Results Matrix, as well as in national legislation (the case of South Africa). The article ends with conclusions about the current state of implementation of the right to clean water in Africa.
An Assessment of Researchers’ Mental Workload and Fatigue While Engaged in Research Using Machine Learning and NASA-TLX
Authors:   Lecturer, Department of Industrial and Production Engineering, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, Muhammad Shoyeb , Akand Md. Rabiul , Tamim Fahim Faisal , Talapatra Subrata , Biswas Sarojit Kumar , Rahman Md. Sumon , Roy Rakesh
Published: February 2025

Objectives: This research aims to identify the prime predictors of researchers’ cognitive fatigue and mental workload while engaged in research endeavors using Binary Logistic Regression and NASA-TLX. Methods: The Mental Fatigue level and workload of seventy-nine researchers were assessed using the Samn-Perelli Fatigue Scale and NASA-TLX on a two-month survey. Then, the prime predictors of Fatigue were identified using binary logistics regression, and the significant differences among NASA-TLX mental workload dimensions were detected at different work shifts and time points through paired sample t-tests. Findings: Paired sample t-test reveals a significant difference between before and after research work mental fatigue scores (p<0.001) as well as baseline fatigue between morning and afternoon (p<0.000). The p-values for baseline fatigue, the shift being worked (morning or afternoon), and the average NASA-TLX score are less than 0.05 in the binary logistic regression, which makes them the three main predictors of mental fatigue in research work. The mean score for ‘Mental demand’ was 80, the highest NASA-TLX dimension, which shows a significant difference with all other dimensions except ‘effort.’ Therefore, these two dimensions contribute the most to mental fatigue. Overall, researchers can reduce their mental fatigue by avoiding working the afternoon shift, managing their mental demands and effort effectively, and not engaging in the research work while feeling tired. Novelty: Employing the NASA-TLX combined with the binary logistic regression model, which can predict the primary predictors of mental fatigue and cognitive workload experienced by researchers and scholars.

Keywords: NASA-TLX, ML, Mental Fatigue, Binary Logistic Regression, Cognitive Ergonomics
Extraction and Sequencing of High Molecular Weight Genomic DNA from Auxenochlorella protothecoides using the Oxford Nanopore Technologies MinION Platform. v1
Authors: J. Camacho Dimitrios , J. Craig Rory , S. Merchant Sabeeha
Published: February 2025

This protocol describes a method for extracting and sequencing high molecular weight DNA fromAuxenochlorella protothecoides (UTEX 250). The protocol incorporates DNA purification steps where RNA is degraded, larger DNA fragments (>10 kb) are enriched, and DNA nicks are repaired. Sequencing libraries are prepared from the resulting high molecular weight DNA using the Ligation Sequencing Kit (version 14 chemistry) and sequenced using the Oxford Nanopore Technologies MinION (Mk1B model). POD5 files are generated, and bases are called using the MinKnow’s built-in Dorado base caller. With just a single flow cell, the entire genome of Auxenochlorella protothecoides (approximately 44 Mbp in diploid size) can be sequenced at a coverage depth of 50x. This method reliably produces 30 kb (N50) reads which can be used to resolve repetitive regions, assess large structural rearrangements, and detect off target integrations of gene editing cassettes. Additionally, methylated bases such as 5mC, 5hmC, and 6mA can be distinguished from canonical bases using the Dorado base-caller, thus allowing for the analysis of epigenetic methylation profiles.
Multi-Site Optic Fiber Implants v1
Authors: Amaya Avalon , M. Hagihara Kenta , Ouellette Benjamin , Grasso Conor
Published: February 2025

This protocol describes the surgical procedure, instrumentation, and reagents necessary for implanting optic fiber probes involving injection(s) and headpost into an adult mouse brain for in-vivo fiber photometry and/or optogenetic manipulation procedures.
Nuclei Isolation Protocol Multiome 10X Genomics v1
Authors: Pokhrel Narayan , Telese Francesca
Published: February 2025

Nuclei were isolated from frozen rat brain tissue for Chromium Next GEM Single Cell Multiome ATAC + Gene Expression assay (10 X Genomics). The protocol allowed us to obtain good quality individual nuclei with intact nuclei membrane. The isolated nuclei were assessed for transposition reaction followed by GEM (Gel beads-in-emulsion) generation and barcoding in order to simultaneously profile epigenetic landscape and gene expression in the same nuclei. The protocol is optimized to prevent wetting failure due to nuclei clogging during GEM generation step and to reduce detection of ambient RNA.
Measurement of Extracellular Dopamine Release During Self-Stimulation Using Fast-Scan Cyclic Voltammetry
Authors: Lebedev Andrei A.
Published: February 2025

Relevance. Regulation of extracellular dopamine levels in the nucleus accumbens is a critical component of the brain’s internal reinforcement mechanisms. The development of fast-scan cyclic voltammetry (FSCV) has made it possible to monitor the dynamics of phasic dopamine release on a timescale consistent with behavioral responses. However, data on extracellular dopamine levels during self-stimulation responses remain contradictory.
Objective. To analyze dopamine release patterns in the nucleus accumbens during ventral tegmental area (VTA) self-stimulation using FSCV.
Materials and Methods. Male Wistar rats were implanted with electrodes for self-stimulation and for monitoring extracellular dopamine levels. Dopamine release was recorded telemetrically in freely moving rats. Dopamine release was assessed based on changes in its extracellular levels in the nucleus accumbens in vivo using FSCV. VTA stimulation was conducted in FR1 mode with bursts of rectangular electrical pulses triggered by head raising at an elevation of 380.
Results. Тhe initial head raise and subsequent delivery of reinforcing stimulation caused an increase in the FSCV signal, which gradually decreased over time. Dopamine release during self-stimulation remained consistently higher than the baseline dopamine level recorded before learning the response. We did not observe a strict correlation between the amplitude and timing of dopamine release and the intensity of self-stimulation responses. Peak dopamine concentration during the electrical stimulus increased and remained elevated for at least the following 20 head raises. Elements of exploratory behavior persisted despite fluctuations in dopamine levels. Dopamine release during the first 5 minutes of the experiment gradually decreased every two minutes. After prolonged self-stimulation, dopamine release declined every 0.5 minutes.
Conclusion. Our findings agree with the hypothesis of a fluctuating emotional continuum that underlies the brain’s reinforcement mechanisms. Dopamine levels seemingly reflect the regulatory processes involved in approach and avoidance mechanisms during self-stimulation and may result from the synthesis of “anticipatory reinforcement” (motivational arousal) followed by a state of satisfaction after the motor act.
Dr. Per-Ingvar Brånemark: A pioneer in osseointegration and modern dental implants
Authors: Newaskar Prabha Shakya , Madanshetty Pallavi , Rao Harikesh , Kamath Sujatha
Published: February 2025

Dr. Per-Ingvar Brånemark MD, PhD (May 3, 1929 - December 20, 2014), revolutionized modern dental implantology through his groundbreaking work on “Osseointegration”. Initially focusing on microcirculation in rabit bone, Brånemark's accidental discovery of titanium's ability to integrate with bone laid the foundation for his pioneering dental implant innovations. In 1965, he applied this concept to dental implants, offering long-term solutions for patients with tooth loss. His "ad modum" protocol introduced a two-stage procedure, later to be simplified into the Brånemark Novum protocol for same-day rehabilitation of the edentulous mandibles.

Beyond dentistry, Brånemark expanded osseointegration's applications to medicine, including bone-anchored hearing aids (BAHA) and implant-supported maxillofacial prostheses. These innovations transformed patient care, enhancing mobility for amputees and providing aesthetic and functional solutions for facial deformities. His work on zygomatic implants addressed severe bone loss in the maxilla, further advancing implantology.

Brånemark's legacy is a global impact on patient care, interdisciplinary research, and numerous honors. His discoveries continue to drive advancements in biomaterials and reconstructive techniques, underscoring his commitment to improving quality of life. From dental implants to osseointegrated prosthetics, Brånemark's vision and perseverance remain central to modern medicine and dentistry. The current year signifies the tenth anniversary of Brånemark’s demise. His memory is deeply ingrained, and he will be revered for generations. This article is being presented to commemorate his life, his scientific contributions, and the profound effects of his work on healthcare.
Comparative evaluation of flexural strength of heat polymerized polymethylmethacrylate denture base material reinforced with silanized titanium dioxide nanoparticles and silanized aluminium oxide nanoparticles–An in vitro study
Authors: Ghagas Srushti Ravindra , Waghmare Anagha , Deshpande Saee , Joshi Jayashree , Pande Neelam
Published: February 2025

: he denture base, which supports artificial teeth and rests on the oral mucosa, is commonly made from Polymethyl methacrylate (PMMA), introduced by Dr. Walter Wright in 1937. PMMA is popular for its ease of processing, low cost, light weight, and aesthetic appeal, but it has drawbacks such as low mechanical strength, brittleness, and a high coefficient of thermal expansion, leading to fractures, particularly under functional stress. Research has focused on incorporating metal oxide nanoparticles into PMMA to improve its mechanical properties and antimicrobial activity.

To assess and compare the flexural strength of heat polymerized polymethyl methacrylate denture base material reinforced with 1% silanized aluminium oxide nanoparticles and 3% silanized titanium dioxide nanoparticles to that of heat polymerized polymethyl methacrylate denture base material.

: Total 90 specimens were prepared, 30 each for PMM denture base material without reinforcement (group C), PMM reinforced with 1% Aluminium oxide nanoparticles (group A) and PMM reinforced with 3% Titanium dioxide nanoparticles (group T) respectively. Flexural strength was tested with universal testing machine at a 5mm/minute crosshead speed.

Flexural strength testing on specimens showed a highly significant difference across the three groups (p < 0.0001). Significant differences were found between Group C and both Group A (p < 0.000001) and Group T (p < 0.000001), while no significant difference was observed between Group A and Group T (p = 0.647).

Reinforcement with nanoparticles increased the flexural strength, with 1% silanized aluminium oxide nanoparticles showing a highly significant improvement. However, no significant difference was found between specimens reinforced with 1% silanized aluminium oxide (Group A) and 3% silanized titanium dioxide nanoparticles (Group T).
An in vitro study to evaluate the shade variation observed in ceramic restorations as affected by the different substructure materials using spectrophotometer
Authors: Nischal Kunal , Rao Sapna , Malhotra Puja , Sanan Reshu , Phukela Sumit , Singh Diksha
Published: February 2025

: Shade selection is one of the most important aspect of achieving optimum esthetics. Shade selection is done manually in most of the dental clinics with the help of commonly available shade guides. However, appropriate shade reproduction is still a challenge in cosmetic dentistry. Porcelain fused to metal restorations have been considered as the gold standard, however with increasing demands in esthetic and with advent of newer materials , crowns can now be fabricated free of metal ie, all ceram or porcelain fused to zirconia restorations. These restorations besides being highly esthetic have strength comparable to metal.

: This study evaluated the effect of different substructure i.e. metal, zirconia and lithium disilicate on resulting shade in comparison with the commercially available shade guide and to determine whether single shade tab is suitable for different substructure.

: 45 disc samples were fabricated with respect to metal, zirconia and lithium disilicate (15 each) and commercially available shade tab used as control.

: Compared with control group, Porcelain fused to metal was closest to shade tab as compared to Porcelain fused to zirconia and Lithium disilicate showed significant shade deviation.

: Different shade tabs should be made available for different substructures.

: Inspite of development of newer materials and newer technologies, shade selection is still carried out with the help of commercially available shade guides which donot consider the change of material or the advances in materials that have taken place over the years. Hence, the dental profession is still plagued with the problem of accurate reproduction of tooth color.
Precision with semi-precision attachment using CAD/CAM technology for a mandibulectomy patient: A case report
Authors: Thakur Preeti , Cleetus Annie , Huda Irfanul , Anand Santosh , Kadao Mohan
Published: February 2025

Rehabilitation of mandibular defects post-marginal mandibulectomy presents significant challenges due to altered anatomy, reduced denture-bearing areas, and compromised muscle attachments that affect tongue mobility, speech, and mastication. Traditional implant-supported options may be unsuitable for patients with insufficient bone support, necessitating alternative prosthetic approaches to restore function and aesthetics.A 17-year-old male underwent a marginal mandibulectomy for odontogenic keratocyst, resulting in a Cantor and Curtis Type V defect. Examination revealed limited residual dentition and insufficient bone volume for implants. The patient reported difficulties with mastication and speech, requiring a stable, retentive prosthesis that would not exacerbate the altered mandibular anatomy.A removable cast partial denture with semi-precision attachments was fabricated using CAD/CAM technology for accuracy and ease of customization. This approach provided necessary retention, stability, and comfort while accommodating the anatomical limitations. The patient reported significant improvements in mastication, speech, and aesthetics, along with high satisfaction.

Semi-precision attachments offer enhanced stability in cases where conventional direct retainers may be insufficient, distributing occlusal loads effectively across limited supporting structures. CAD/CAM technology facilitated precise attachment placement and minimized chairside adjustments, further improving patient comfort and prosthesis function.For patients with mandibular defects unsuitable for implants, a removable prosthesis with semi-precision attachments, designed with CAD/CAM technology, provides a reliable, conservative alternative. This approach achieves satisfactory functional and aesthetic outcomes, demonstrating the value of modern digital design and attachment-retained prostheses in complex rehabilitative cases.
A novel technique to stabilize the bite-block with the rubber dam frame using a connector
Authors: Choudhary Deebah , Gaur Aditi , Rao Ajay Singh , Karande Rutvi
Published: February 2025

The present article describes a novel technique by which the bite-block can be easily and adequately stabilized with the help of the rubber dam frame which not only eliminates the possibilities of untoward complications but also gives freedom to the operator to work for longer hours without the fear of causing any TMJ-related problems to the patients.

Bite-block or mouth prop can be efficiently stabilized with rubber dam isolation.
PROSOPOGRAPHICAL METHOD IN STUDYING SOCIAL AND ECONOMIC DEVELOPMENT OF THE VILLAGE KURSK PROVINCE IN THE FIRST QUARTER OF THE 20TH CENTURY (ON THE EXAMPLE OF THE VILLAGE OF FENTISOVO SHCHIGROVSKY DISTRICT OF KURSK PROVINCE)
Authors: Konishchev Andrey
Published: February 2025

Currently, research is being conducted in the field of local history that addresses a wide range of issues related to the history of peasantry. The aim of this research is not to produce fundamental historical works, but rather to gradually reconstruct the history of their native village. Our article falls into this category of research. It represents an attempt to reconstruct the socio-economic history of Fentisovo village, Shchigrovsky district, Kursk province, using new methods of historical research - prosopography. As a result, we were able to create a collective portrait of the villagers and conduct a comparative analysis.
Phytoextraction of Pollutants by Aquatic Plants at Phyto-treatment Facilities of Industrial Wastewater of "Karelsky Okatysh" JSC
Authors: Bryantsev A.V.
Published: February 2025

The process of bioremediation of anthropogenic water bodies based on the technology of transformation of anthropogenic water bodies into nature-like wetland ecosystems is studied. The results of laboratory studies of accumulation of various pollutants, in particular heavy metals and mineral nitrogen compounds, by local moss communities in phytomodules on waste water settling ponds of the enterprise "Karelsky Okatysh" JSC are presented. The degree of efficiency of higher aquatic plants in industrial wastewater treatment is evaluated. It is concluded that the results obtained can be used for further development of phyto-purification systems in Russia.
Refining of Mixed Plastic Waste to Produce Low Pour Point Diesel Fuel
Authors: Bogomolova T.S. , Smirnova M.Yu. , Nadeina K.A. , Salomatina A.A. , Krestyaninova V.S. , Vatutina Yu.V. , Mukhacheva P.P. , Klimov O.V.
Published: February 2025

The possibility of obtaining low pour point diesel fuel by dewaxing of feedstock containing hydrotreated thermolysis oil obtained from a mixture of plastic wastes is presented. It has been established that in the process of dewaxing the n-alkanes of the feedstock, regardless of the length of the carbon chain, undergo almost complete conversion, leading to the improved low-temperature and rheological properties of the hydrotreated product. It is concluded that the obtained petroleum products are characterized by a high degree of environmental purity, since they do not contain chlorine, and the concentration of sulfur- and nitrogen-containing compounds, as well as polycyclic aromatic hydrocarbons, is minimal.
Modeling and Technical and Economic Analysis of Supercritical Fluid Methods for Industrial Wastewater Treatment of "Kazanorgsintez" PJSC in Relation to Model Runoff
Authors: Gabitova A.R. , Aetov A.U. , Zaripov Z.I. , Gumerov F.M. , Usmanov R.A. , Mazanov S.V.
Published: February 2025

In the software package Aspen Hysys (version 12) with the help of Aspen Process Economic Analyzer, a technical and economic comparison of the possibilities of two different variants for phenol-containing aqueous water waste treatment at "Kazanorgsintez" PJSC using the extraction process and as a result of oxidation of organic components of the water runoff was carried out. Modeling and scaling of these processes for a runoff fed at a mass flow rate of 1000 kg/h was performed An estimation of operating costs for realization of each of the investigated variants is given.
Modeling of Migration of Polycyclic Aromatic Hydrocarbons in Groundwater Considering Biological Degradation
Authors: Afanasyеva A.A. , Andreeva E.A. , Nazarenko D.I. , Lapushkin M.Yu. , Vasilyeva G.K. , Shvetsova-Shilovskaya T.N.
Published: February 2025

The problem of groundwater pollution by benz(a)pyrene and other polycyclic aromatic hydrocarbons (PAHs), the sources of which may be accumulators of industrial wastes from coke-chemical and oil-refining enterprises, is considered. It is shown that as a result of microbial degradation of benz(a)pyrene in soil and groundwater, the formation of carcinogenic substances with good solubility and low ability to sorption on soil particles is possible, which contributes to their rapid accumulation and migration in groundwater. With the help of mathematical modeling and developed software, the distribution of benz(a)pyrene and its degradation products in groundwater from the coal tar waste storage pond located in Ulan-Ude was assessed. Marker substances for monitoring the environmental situation around industrial waste disposal facilities containing benz(a)pyrene and other PAHs are proposed.
Ecological-Geochemical Assessment Bottom Sediments of Tributaries of the Ural River under Conditions of Technogenic Influence
Authors: Kuzhina G.Sh. , Suyundukov Ya.T.
Published: February 2025

The spatial variability of the content of heavy metals in bottom sediments of the right tributaries of the river Ural is presented. Leading metals were identified in the geochemical associations of sediments of watercourses in areas of intense technogenic impact, associated with the specifics of existing industries. Data are presented for calculating the coefficient of average accumulation and the total indicator of soil pollution, which allows one to assess the level of pollution and the degree of sanitary and toxicological hazard of the rivers under study.
Development Agency of Pancasila Ideology Policy Evaluation and Structural Design
Authors: Aritonang Dinoroy Marganda , Shafrudin Refri , Wirjatmi Endang , Anwar Saekul
Published: February 2025

This research examines the Pancasila Ideology Development Agency (BPIP’s) bureaucratic simplification process. Bureaucratic simplification has eliminated Echelons III and IV by altering their functions. The policy impacts broadly on organizational structure, design changes, performance, personnel, and the workplace. The study used a mixed method with a focus on qualitative approaches. Interviews, observations, questionnaires, and source triangulation were used to collect data and evaluate its validity. The research findings from the CIPP dimension show that the bureaucratic simplification agenda are still not performing well. It is acknowledged that some indicators related to its adoption are yet to produce favorable results. It is concerned with changes in the work system that each work unit has not fully recognized and adjusted. As a result, it is critical to strengthen the work system by formalizing the squad team system, increasing productivity, and establishing a clear division of tasks and authority among deputies, directorates, and functional groups. Deputies and directors encounter difficulties, in overseeing and directly managing job completion in functional roles since the middle line previously occupied by the head of the sub directorate and the head of the section has been eliminated. Furthermore, structural changes are required to shift the structural function of general administration from the Main Secretariat Unit to the Deputies and Directors in BPIP. It indicates that the functionalization and simplicity of bureaucracy still need organizational structures.
Development of MSMEs Potential Based on Pineapple Raw Materials in Prabumulih City
Authors: ‎ Ermanovida , Mirani Dwi , Agustina Sylvie , Putri Aulia Utami , ‎ Zakiyah
Published: February 2025

Micro, small, and medium enterprises (MSMEs) play a crucial role in supporting the economy. However, MSMEs still face several challenges, such as limitations in human resources, access to capital, technological knowledge, as well as marketing and infrastructure issues. In Prabumulih City, South Sumatra, MSMEs are developing rapidly across various sectors, including fashion, food, beverages, and handicrafts. Nevertheless, the lack of organization in MSME data in Prabumulih poses an obstacle to maximizing its potential, particularly concerning pineapples. Therefore, this research aims to elucidate and examine the development of MSME potential based on pineapple products in Prabumulih City. The methodology employed in this study is descriptive qualitative. The research findings indicate that the development of MSMEs based on local products such as pineapples should be a primary focus for the Prabumulih City government. Various innovations, such as tutilizing pineapple fibers and product diversification based on pineapples, have been implemented to enhance competitiveness in both local and national markets. However, challenges related to MSME data management and the use of marketing technology remains underutilized or insufficiently adopted. Consequently, the integration of MSME data and further support in the application of digital technology are essential to strengthen the position of MSMEs in the market.
Design of Lubuklinggau City Policy: A Review of the Establishment of Local Regulations on the Guidance and Development of Micro and Small Industries
Authors: Aziman Muhammad Fauzan , Hakim Kahar
Published: February 2025

This research examines the policy formulation process for establishing a regional regulation on the guidance and development of micro and small industries in Lubuklinggau City. This initiative was taken by the Lubuklinggau City government in 2024 to address various challenges in industrial development in the city. Using qualitative methods with data collection techniques through focus group discussions, interviews, observations, and documentation studies, this research focuses on the seven initial stages of the policy formulation process. The results show that the Lubuklinggau City government has implemented a comprehensive approach, including Regulatory Impact Analysis (RIA) in decision making. Findings revealed a change in policy focus to micro and small industries and stakeholder engagement through public consultation. The analysis also revealed plans to establish an industrial center area and develop an integrated information system for the data collection on micro and small industries. The resulting policy design combines aspects of guidance and development, including training programs, mentoring, and strategies for developing industrial infrastructure and resources. Based on these findings, the research recommends further studies that include policy implementation and evaluation stages to understand this policy’s long-term impact and effectiveness in supporting the growth of micro and small industries in Lubuklinggau City.
Revitalizing Malang's Environmental Future: Harnessing the Green Economy through Collaborative Governance
Authors: Novita Asti Amelia
Published: February 2025

The decline in the Environmental Quality Index (IKLH) in Malang City highlights worsening environmental conditions, particularly in water quality, which saw a drastic reduction from 69.26 in 2020 to 29.26 in 2022. This significant drop reflects the ineffective management of natural resources, including water, land cover, and air quality. With Malang’s IKLH standing at 56.31 in 2022, the need for urgent improvement is clear. Addressing this requires concrete actions, starting with an analysis of environmental governance that engages key stakeholders such as the environmental agency, health agency, public works and spatial planning agency, and local environmental communities. A collaborative governance approach, grounded in the Green Economy Index (GEI), is proposed, integrating social, economic, and environmental dimensions. This study utilizes soft systems methodology and Penta helix analysis, incorporating perspectives from the government, community, academia, the private sector, and media. The aim is to develop an integrated governance model to enhance Malang’s environmental quality. The analysis underscores a lack of coordination between government agencies, environmental groups, and the public, which hampers effective environmental management. By implementing the GEI framework, the proposed model seeks to address these gaps and optimize Malang City’s environmental quality.