bluuebunny/crossref_metadata_2025 huggingface dataset:
General Scientific Bases of Social Competence Definition as a Qualitative Characteristic of Students Socialization Process
Authors: Vasyliuk Т. , Kuts М.
Published: April 2022

One of the main priorities of modern higher education is training of specialists with a clearly defined and measurable level of professional and social competence. The basic competencies of future specialists are determined by the requirements of employers, as well as dictated by public expectations, so the problem of their formation is a priority today in the process of forming a personality in higher education.International norms stipulate that the most important paradigms of such potential include: productivity as a result of effective activities aimed at improving personal status, income; equality, which is understood as equality of opportunity; stability that allows access to the achievements of world civilization; empowerment, when it is assumed that social development is carried out not only for the benefit of the individual, but also through their own efforts.
CR -hypersurfaces of conformal Kenmotsu manifolds with ξ-parallel normal Jacobi operator
Authors: Abdi Roghayeh
Published: April 2022

In this paper, we study CR-hypersurfaces of a conformal Kenmotsu manifold with a ξ-parallel or Lie ξ-parallel normal Jacobi operator.
On Bessel and Riesz-Fisher systems with respect to Banach space of vector-valued sequences
Authors: Isnailov Migdad I.
Published: April 2022

The paper deals with Bessel systems and Riesz-Fisher systems in Banach spaces with respect to some Banach spaces of vector-valued sequences. The notions of ~X-Bessel systems and ~X -Riesz-Fisher systems were introduced and the characterization of such systems was established. ~X -frames and ~X -Riesz g-bases are also studied in this paper. The relations between them are obtained.
Three dimensional Sasakian manifolds admitting η-Ricci solitons
Authors: Kar D. , Majhi P.
Published: April 2022

In this paper we characterize the three dimensional Sasakian manifolds admitting η-almost Ricci solitons. After the introduction, in section 2, we study three dimensional Sasakian manifolds. In section 3, we prove that an η-Ricci soliton in Sasakian manifolds satisfying the curvature property R.Q = 0 is shrinking and reduces to Ricci soliton. In section 4, we show that the necessary and suficient condition for a Sasakian manifold not admitting a proper η-Ricci soliton is that it is Ricci symmetric. In sections 5 and 6, we study projectively at and concircularly at Sasakian manifold of dimension 3 respectively and find the type of an η-Ricci soliton on such manifold. The next section is devoted to the study of such a manifold admitting η-Ricci soliton and we prove some equivalent conditions. Finally, in section 8, we prove that in a three dimensional Sasakian manifold an η-Ricci soliton becomes Ricci soliton if and only if it is Ricci pseudo-symmetric.
Some properties of pseudo-slant submanifolds of a Sasakian manifold
Authors: Kumar S. , Pandey S. , Prasad R.
Published: April 2022

In this paper, we study pseudo-slant submanifolds of a Sasakian manifold. We find some results and investigate the integrability conditions of distributions which are involved in the definition of pseudo-slant submanifolds. Finally, we obtain the necessary and sucifient condition for a pseudo-slant submanifold to be pseudo-slant product.
On λ-pseudo bi-starlike functions related to some conic domains
Authors: Murugusundaramoorthy G. , Sokol J.
Published: April 2022

In this paper, we introduce a new class ℒ Σ λ (φ) of λ-pseudo bi-starlike functions and determine the bounds for |a2| and |a3| where a2, a3 are the initial Taylor coefficients of f ∈ ℒ Σ λ (φ). Furthermore, we estimate the Fekete-Szeg¨o functional for f ∈ ℒ Σ λ (φ).
On univalence of a new integral operator
Authors: Aldea C.L. , Pescar V.
Published: April 2022

In this paper, we define a new integral operator and we obtain univalence criteria for this integral operator.
Decision support system choosing software testing strategy
Authors: Chernov V. , Dorokhova L. , Dorokhov O. , Egorovskaya G.
Published: April 2022

The problem of choosing the optimal software testing strategy is considered. The classification of testing approaches is given. The factors influencing the choice of type of testing are investigated. It is shown how these factors can be used to make decisions. Algorithms for choosing the type of testing are developed. The proposed and developed decision support system is implemented in practice.
Some inequalities for operator weighted geometric mean
Authors: Dragomir Silvestru Sever
Published: April 2022

In this paper, by the use of some recent Young's type scalar inequalities we obtain some inequalities for the weighted geometric mean of two positive operators on a complex Hilbert space.
Jenseits unbefristeter Professuren — inmitten der Sorge um das wissenschaftliche Feld?
Authors: Leinfellner Stefanie , Simon Stefanie
Published: April 2022

Im Beitrag werden Arbeitsverhältnisse jenseits von unbefristeten Professuren im Licht von Befristung, Prekarisierung, Leistungsorientierung und Selbstoptimierung thematisiert, um Strukturen und Bedingungen des deutschen Wissenschaftssystems im Kontext aktueller Diskurse in den Blick zu nehmen. Entlang dessen werden machtvolle Ungleichheitslinien und Praktiken im Wissenschaftsfeld beleuchtet und auf die Bedingungen von wissenschaftlichem Diskurs und Wissensproduktion bezogen.
Core muscle strength can be reliably measured using a novel isokinetic device: An intra-observer study
Authors: Mulder Marit L. , Van den Steen Elke , De Neve Jan , Weir Adam
Published: April 2022

BACKGROUND: Core strength is an important aspect of physical fitness. A dynamometer was developed to measure isokinetic core muscle strength in multiple planes of motion. Establishing the reliability is needed before it can be used in practice. OBJECTIVE: Examine the intra-observer reliability of a trunk isokinetic dynamometer. METHODS: 31 participants were recruited. Tests were performed twice with an interval of 5–9 days by the same observer. Testing included rotation, flexion/extension and lateral flexion at speeds of 90∘/s and 60∘/s. The main outcome measure was peak torque (PT). The secondary outcomes included peak torque angle (PTA), time to peak torque (TTPT) and compensatory torques (CompTQ). The intra-observer reliability was investigated using intraclass correlation coefficients (ICC). RESULTS: Peak torque reliability was good to excellent (ICC = 0.70–0.91), whereas the reliability of the PTA (ICC =-0.04–0.56) and TTPT (ICC = 0.01–0.68) were poor to moderate. CompTQ reliability was moderate to good (ICC = 0.20–0.88). CONCLUSIONS: The intra-observer reliability of the isokinetic measurement of core strength peak torque was good. The secondary outcomes peak torque angle and time to peak torque were less reliable and the compensatory torques showed moderate to good reliability. This isokinetic dynamometer could have useful applications in the field of sports medicine and rehabilitation.
Modified orthopedic traction system for cervical and lower limb rehabilitation
Authors: Fidelis Obinna P.
Published: April 2022

BACKGROUND: Orthopedic tractions can be employed in the rehabilitation of patients suffering from problems affecting the spine, as well as the upper and lower extremities but the high costs of using tractions due to prolonged hospital stays is a major disadvantage particularly in low-income economies. OBJECTIVE: The objective of this study was to design and develop a two-way adjustable traction system that accommodates both cervical and lower limb rehabilitation and improves limb and neck positioning. METHOD: The production process involved the use of computer-aided design (CAD) as well as other manufacturing procedures like material selection, welding, and drilling. The system was tested for stability to be sure it does not fail under large loads. RESULT: A functional and easy-to-install two-way orthopedic traction system for both hospital and home use was developed, installed and tested. The dimensions and adjustability would ensure that it can be used for children and adults. CONCLUSION: This study describes a device that can be used in hospitals. When used at homes, it can reduce the cost of medical bills, and provide patients with the emotional/psychological benefits of being cared for in a familiar environment.
Frontal Metabolites and Alzheimer’s Disease Biomarkers in Healthy Older Women and Women Diagnosed with Mild Cognitive Impairment
Authors: Hone-Blanchet Antoine , Bohsali Anastasia , Krishnamurthy Lisa C. , Shahid Salman S. , Lin Qixiang , Zhao Liping , Bisht Aditya S. , John Samantha E. , Loring David , Goldstein Felicia , Levey Allan , Lah James , Qiu Deqiang , Crosson Bruce
Published: April 2022

Background: Women account for two thirds of the prevalence and incidence of Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Evidence suggest that sex may differently influence the expression of proteins amyloid-beta (Aβ1–42) and tau, for which early detection is crucial in prevention of the disease. Objective: We investigated the effect of aging and cerebrospinal fluid (CSF) levels of Aβ1–42 and tau on frontal metabolites measured with proton magnetic resonance spectroscopy (MRS) in a cohort of cognitively normal older women and women with MCI. Methods: 3T single-voxel MRS was performed on the medial frontal cortex, using Point Resolved Spectroscopy (PRESS) and Mescher-Garwood Point Resolved Spectroscopy (MEGA-PRESS) in 120 women (age range 50–85). CSF samples of Aβ1–42 and tau and scores of general cognition were also obtained. Results: Levels of frontal gamma aminobutyric acid (GABA+) were predicted by age, independently of disease and CSF biomarkers. Importantly, levels of GABA+ were reduced in MCI patients. Additionally, we found that levels of N-acetylaspartate relative to myo-inositol (tNAA/mI) predicted cognition in MCI patients only and were not related to CSF biomarkers. Conclusion: This study is the first to demonstrate a strong association between frontal GABA+ levels and neurological aging in a sample consisting exclusively of healthy older women with various levels of CSF tau and Aβ1–42 and women with MCI. Importantly, our results show no correlation between CSF biomarkers and MRS metabolites in this sample.
Clinical and Imaging Determinants of Neurocognitive Disorders in Post-Acute COVID-19 Patients with Cognitive Complaints
Authors: Andriuta Daniela , Si-Ahmed Cherifa , Roussel Martine , Constans Jean-Marc , Makki Malek , Aarabi Ardalan , Basille Damien , Andrejak Claire , Godefroy Olivier
Published: April 2022

Background: Neurocognitive disorders (NCDs) are a part of the post-acute coronavirus disease (COVID-19) syndrome. No study has specifically evaluated NCDs in post-acute COVID-19 patients with cognitive complaints or their MRI determinants. Objective: To characterize NCDs in post-acute COVID-19 patients with cognitive complaints. The secondary objectives were to assess their clinical and MRI determinants. Methods: We included 46 patients with a post-acute COVID-19 cognitive complaint referred to the Amiens University Hospital Memory Center. They underwent a neuropsychological assessment and 36 had cerebral MRI. The G3 overall summary score was the sum of the mean z scores for the executive function, language, and action speed domains. Neuropsychological profiles were compared in a general linear model. Clinical determinants were analyzed by stepwise linear regression. White matter hyperintensities (WMH) masks were analyzed using parcel-based WMH symptom mapping to identify the locations of WMHs associated with cognitive performance. Results: Repeated ANOVA showed a group effect (p = 0.0001) due to overall lower performance for patients and a domain effect (p = 0.0001) due to a lower (p = 0.007) action speed score. The G3 overall summary score was significantly associated with solely the requirement for oxygen (R2 = 0.319, p = 0.031). WHMs were associated with the G3 overall summary score in the following structures, all right-sided (p < 0.01): superior frontal region, postcentral region, cingulum, cortico-spinal tract, inferior longitudinal fasciculus, internal capsule, and posterior segment of the arcuate fasciculus. Conclusion: Post-acute COVID-19 patients with cognitive complaints had NCD, with prominent action slowing, significantly associated with the acute phase oxygen requirement and a right-sided WMH structure pattern.
Rethinking a Traditional Method of Participation: “Town-Hall Meetings” to Support Family Carers of People with Dementia
Authors: Wiloth Stefanie Sandra , Kiefer Anna , Wittek Maren , Arroyo y Villora Tatjana , Obermeier Monika , Schmitt Eric , Kruse Andreas
Published: April 2022

A growing number of people with dementia, a simultaneous decline of professional caregivers, and changing family structures clearly illustrate the societal relevance of the question of how dementia care can be arranged and delivered in the future. The demand for innovative solutions especially to support family carers requires a deeper insight into their life situation and a focused perception of their needs. This article presents the main hypothesis that specific forms of social integration and participation based on an equal dialogue between family caregivers, the public, and policymakers is needed to achieve that. Therefore, the main point here is to give family caregivers of people with dementia a voice to learn how to better support them in caring as well as self-care. A learning process triggered by a dialogue might result in a higher level of community readiness to implement new forms of support or social innovations. The hypothesis will be supported by John Dewey’s theory of political and democratic learning and the model of transformative learning according to Jack Mezirow indicating that learning particularly succeeds in interpersonal communication. In this context, the Town-Hall Meeting method and its potential to promote interpersonal communication and reflexive learning is discussed. The article addresses an important debate, namely that of how dementia care and support of family carers can succeed. It also sets the direction for future empirical research as the Town-Hall Meeting method might be applicable for gerontological action and participatory research.
Physical Activity and Cognition in Sedentary Older Adults: A Systematic Review and Meta-Analysis
Authors: Zhao Yan , Li Yan , Wang Lijing , Song Zihe , Di Tengsen , Dong Xinyi , Song Xiaohan , Han Xintong , Zhao Yanyan , Wang Bingfei , Cui HuiXian , Chen Haiying , Li Sha
Published: April 2022

Background: Epidemiologic evidence suggests that physical activity benefits cognition, but results from randomized trials in sedentary individuals are limited and inconsistent. Objective: To evaluate the effects of physical activity on cognition among sedentary older adults. Objective: A systematic literature search for eligible studies published up to January 1, 2021, was performed on six international (PubMed, Cochrane Library, Web of Science, Sinomed, FMRS, and OVID) and three Chinese databases (Wanfang, China National Knowledge Infrastructure, and VIP). We estimated the effect of physical activity on the cognition of sedentary elderly by standardized mean differences (SMD) and 95% confidence intervals (CI) using a random-effects model. We evaluated publication bias using funnel plots and heterogeneity using I2 statistics. Subgroup analyses were conducted by baseline cognition, intervention duration, activity type, and country. Results: Seven randomized controlled trials (RCTs) comprising 321 (experimental group, 164; control group, 157) sedentary older adults were included in the meta-analysis. Physical activity significantly improved cognition in sedentary elderly adults compared with controls (SMD: 0.50, 95% CI:0.09–0.92). Subgroup analyses showed significant effects of baseline cognition impairment (SMD: 9.80, 95% CI: 5.81–13.80), intervention duration > 12 weeks (SMD: 2.85, 95% CI: 0.73–4.96), aerobic exercise (SMD: 0.74, CI: 0.19–1.29), and countries other than the United States (SMD: 10.50, 95% CI: 7.08–13.92). Conclusion: Physical activity might have a general positive effect on the cognition of sedentary older adults. Intervention > 12 weeks and aerobic exercise can effectively delay their cognitive decline; however, more rigorous RCTs are needed to support our findings.
Prevalence and Safety of COVID-19 Vaccination in Community-Dwelling People with Dementia: Findings from a Tertiary Memory Clinic in Italy
Authors: Valletta Martina , Canevelli Marco , D’Antonio Fabrizia , Trebbastoni Alessandro , Talarico Giuseppina , Campanelli Alessandra , Sepe Monti Micaela , Di Vita Antonella , Salati Emanuela , Imbriano Letizia , Margiotta Roberta , Barbetti Sonia , Diana Sofia , Buscarnera Simona , Toccaceli Blasi Marco , Salzillo Martina , Pugliese Giuseppe , Vanacore Nicola , Bruno Giuseppe
Published: April 2022

This study aimed to explore the prevalence and safety of SARS-CoV-2 vaccination in individuals with dementia. Patients with mild cognitive impairment or dementia were recruited at a tertiary memory clinic, from March 15 to September 15, 2021. Information on COVID-19 vaccination and adverse events experienced after vaccine administration were collected from caregivers. Two-hundred-seventy subjects were finally recruited. Among them, 253 (93.7%) had received the vaccine and only 69 (27.3%) experienced adverse events. Cognitive and behavioral changes following immunization were only rarely reported. COVID-19 vaccination is safe and well-tolerated in patients with cognitive impairment who should be prioritized in the vaccination campaign.
Physical Activity Intensity and Suspected Dementia in Older Japanese Adults: A Dose-Response Analysis Based on an 8-Year Longitudinal Study
Authors: Nagata Koki , Tsunoda Kenji , Fujii Yuya , Tsuji Taishi , Okura Tomohiro
Published: April 2022

Background: Moderate- to vigorous-intensity physical activity (PA) may reduce the risk of dementia; however, few studies have examined the effects of PA intensity on dementia risk. Objective: To prospectively examine the dose-response relationship of PA intensity with the incidence of suspected dementia in community-dwelling older adults. Methods: We conducted a baseline mail survey with an 8-year follow-up of 3,722 older adults in Japan. We assessed PA levels using the International Physical Activity Questionnaire short form and calculated the amount of time per week spent performing moderate- and vigorous-intensity PA (VPA). Information regarding suspected dementia was obtained from the city database during the follow-up period. Cox proportional-hazard models with age as time scale, and delayed entry and restricted cubic spline regression as variables were used to estimate risk of developing suspected dementia, excluding cases occurring < 1 year after baseline evaluation. Results: The cumulative incidence of suspected dementia during the follow-up period was 12.7%. Compared with those who did not practice moderate-intensity PA (MPA), those who practiced≥300 min (hazard ratio, 0.73; 95% confidence interval 0.56–0.95) of MPA showed a lower risk of developing suspected dementia. Furthermore, when the dose-response relationship was examined, the hazard of developing suspected dementia decreased almost linearly with MPA. A significantly lower hazard was observed from 815 minutes/week. There was no significant association between VPA and suspected dementia. Conclusion: This study suggested that MPA is often practiced in older adults and this PA intensity has a sufficiently favorable effect on dementia prevention.
Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement
Authors: Ashford J. Wesson , Schmitt Frederick A. , Bergeron Michael F. , Bayley Peter J. , Clifford James O. , Xu Qun , Liu Xiaolei , Zhou Xianbo , Kumar Vinod , Buschke Herman , Dean Margaret , Finkel Sanford I. , Hyer Lee , Perry George
Published: April 2022

Wang et al. analyze Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment accuracy as screening tests for detecting dementia associated with Alzheimer’s disease (AD). Such tests are at the center of controversy regarding recognition and treatment of AD. The continued widespread use of tools such as MMSE (1975) underscores the failure of advancing cognitive screening and assessment, which has hampered the development and evaluation of AD treatments. It is time to employ readily available, efficient computerized measures for population/mass screening, clinical assessment of dementia progression, and accurate determination of approaches for prevention and treatment of AD and related conditions.
Computation of the probability of ultimate ruin and some other actuarial quantities under the classical risk model via Fast Fourier Transform
Authors: Das Jagriti
Published: April 2022

The Probability of ultimate ruin under the classical risk model is obtained as a solution of an integro -differential equation involving convolutions and we have used Fast Fourier Transform (FFT) to obtain the approximate values of the probability of ultimate ruin from this integro -differential equation under the situation when the claim severity is modelled by the Mixture of 3 Exponentials and the Weibull distribution. Another application of FFT in ruin theory is shown by means of applying it to obtain the quantiles of the aggregate claim distribution under these claim severity distributions. Extension of the application of FFT is shown by using it to obtain the first moment of the time to ruin under the classical risk model for these distributions. The distributions which have been used are such that one is light tailed and the another is heavy tailed so that a comparison can be made between them on the precision of the actuarial quantities obtained through FFT. FFT has been found to be efficient in obtaining these actuarial quantities when used in conjunction with certain modifications like exponential tilting to control the aliasing error.
A hybrid machine learning framework for e-commerce fraud detection
Authors: Festa Yury Y. , Vorobyev Ivan A.
Published: April 2022

We currently see a large increase in e-commerce sector; it is becoming a central trend in the banking industry. Fraudsters keep up with modern technologies, and use weak points in human psychology and security systems to steal money from regular users. To ensure the required level of security, banks began to apply artificial intelligence in their anti-fraud systems. Fraud detection can be formulated as a classification problem with a case-based reasoning or knowledge extraction task with unbalanced classes. In this paper we present a framework of models based on various approaches of artificial intelligence, such as neural networks, decision trees, copula models and others to recognize payment behavior of fraudster. The considered framework is evaluated with different metrics and implemented in an actual anti-fraud system, which leads to an improvement of the system performance. Finally, the interrelation between the anti-fraud system indicators and banks operational risks is discussed in this paper.
The association of disability status with job tenure for U.S. workers
Authors: Brucker Debra L. , Henly Megan , Rafal Marisa
Published: April 2022

BACKGROUND: Job tenure is a useful economic indicator. To employees, longer job tenure creates higher rewards in pay, promotion opportunities, and job security. For employers, there are fewer costs in recruitment and retraining when job turnover is low. Marginalized populations, such as persons with disabilities, may find work in various economies, but retention is more difficult. They are often the first to be laid off in struggling economies. OBJECTIVE: The purpose of this study is to highlight differences in individual and employment-related factors associated with job tenure for American workers with and without disabilities. METHODS: Using newly available survey data (N = 1,538), OLS regression is used to estimate job tenure for workers with and without disabilities, controlling for worker sociodemographic characteristics, a job quality index, and job characteristics. All disability types are examined. RESULTS: Multivariate results show that workers with disabilities have shorter job tenure than others when controlling for job quality, individual characteristics and job characteristics. CONCLUSION: Employees with disabilities have shorter job tenure than those without. Given the benefits of lengthened job tenure, further efforts should be made to explore this issue and to develop effective strategies that help those with disabilities retain jobs long term.
Effect of slit lamp table design on neck position and the prevalence of neck pain in eye care professionals
Authors: Wasserman Jennifer B. , Bustos Karly M. , Coombs Stephen D. , Cronan Connor M. , Dimmitt Sarah K. , Leberman Jacob R. , Tomaka Victoria A. , Wasserman Peter
Published: April 2022

BACKGROUND: Ophthalmologists/Optometrists have a high incidence of neck pain. Little research has been conducted on specific equipment that predisposes these professionals to cervical discomfort. OBJECTIVE: Primary purpose: to determine if neck position is altered by slit lamp table design. Secondary purpose: to confirm the prevalence of neck pain in eye care professionals. METHODS: A survey of work-related pain was administered to 36 subjects (8 ophthalmologist, 2 optometrists, 26 technicians). The craniovertebral (CV) angle was measured in each subject in three separate positions (resting posture, best posture, slit lamp posture) between two different slit lamps/tables: slit lamp-deep and slit lamp-shallow. RESULTS: 79% of subjects reported neck pain in the last 6 months. The mean CV angle of all subjects at resting posture, best posture, and both slit lamp postures differed significantly. There was also a difference in CV angle between slit lamps. CONCLUSION: Neck pain is more prevalent in eye professionals than in the general population. The use of slit lamps promotes a forward head posture which decreases the CV angle, putting the user at risk for neck pain. By altering slit lamp table design, the CV angle of eye care professionals can be increased, reducing the risk for neck injury.
Embitterment among the unemployed: A multiple mediation model of belief in a just world
Authors: Shin Jeonghoon , You Myoungsoon
Published: April 2022

BACKGROUND: The negative consequences of job loss on financial and psychological quality of life have been well documented. OBJECTIVE: This study evaluated the level of unemployed individuals’ embitterment and the mechanism by which negative life experiences increase embitterment by lowering the belief in a just world (BJW). METHODS: A survey was administered to 1,074 unemployed Korean adults who visited a regional Center for Employment and Welfare. Question items included the Korean version of posttraumatic embitterment disorder (PTED) self-rating scale, the BJW (personal and general) scale, negative life events, and sociodemographic characteristics. RESULTS: Only 45.9% of the participants were categorized as being in a ‘normal state,’ indicating that many of the unemployed were emotionally embittered. There was a positive direct effect of an increase in negative life events on embitterment. Negative life events also significantly and indirectly affected embitterment through personal BJW. CONCLUSIONS: Embitterment was prevalent among the unemployed participants and embitterment was a reactive emotion following personal downgrading, not so much related to conditions in the world at large. Thus, we recommend developing a screening program to detect extreme embitterment and an interventional program to help people better cope with emotional stress due to job loss. Efforts should be made to restore their violated expectation and trust that they would be treated in a just and fair way.
In Vitro Investigation of Therapeutic and Anti-Coagulant Article DOI: Properties of Allium Sativum L. on Human Plasma
Authors: Sadaf Sarfraz  , Khan Muhammad Ismail , Shomaila Skinandar  , Ismail Anam
Published: April 2022

The current study was conducted to compare the anti-coagulant activity of different solvent-extracted fractions of garlic in a human blood sample in vitro. Two different solvents, namely rectified spirit and reverse osmosis (RO) water, were used to achieve the desired results. We used multiple extracting approaches to prepare different extract fractions of Allium sativum, both in ethanolic and aqueous extracts. These approaches included maceration, decoction, and soxhlet extraction methods. The concentration of each extract fraction was subjected to a primarily anti-coagulant screening method applied to a human blood sample in vitro by calculating the prothrombin time of human blood coagulation. The anti-coagulant activity of the extracts was determined by measuring the changes in prothrombin time with a null hypothesis value of p< 0.05. Additionally, a qualitative study of active phytochemical elements, such as alkaloids, flavonoids, steroids, proteins, carbohydrates, terpenoids, tannins, and glycosides was also conducted. The results indicated that all garlic extract fractions have a significant anti-coagulant potential. However, at 5 ppm concentration, soxhlet extraction extract showed the maximum anti-coagulant potential. Moreover, Garlic's aqueous extract also showed a significant anti-coagulant effect on human plasma. This observation conforms to the finding that the soxhlet extracted sample of garlic showed the highest activity of platelet aggregation inhibition. Furthermore, it was determined that aqueous and ethanolic extracts of Allium sativum showed a significant potential of anti-coagulation by comparing the current results with positively controlled EDTA and double oxalate acting as synthetic anti-coagulants.
Absceso renal en Pediatría: un desafío diagnóstico
Authors: Jimenez Martha , Gajardo Zurita Macarena , Bolte Lillian , Lazcano Andrea , Salgado Ignacio
Published: April 2022

El absceso renal es una entidad poco frecuente en pediatría. Objetivo: reportar presentación clínica, diagnóstico y terapia en una cohorte de 20 niños con absceso renal. Pacientes y Método: estudio retrospectivo de casos de absceso renal durante un periodo de 10 años en el Hospital Roberto del Río. Se analizaron las características clínicas, de laboratorio, imagenológicas y el tratamiento realizado. Resultados: 20 casos, 65% mujeres, mediana de edad de 3,6 años. La presentación clínica más frecuente fue fiebre, vómitos y síntomas urinarios bajos. El 80% presentó elevación de parámetros inflamatorios y 88% urocultivo positivo, siendo el microorganismo más frecuente Escherichia coli (77,8%). El diagnóstico se realizó mayoritariamente con ecografía renal. El 95% requirió solo tratamiento antibiótico. Se pesquisó reflujo vesicoureteral en 28% de los pacientes sin control de esfínter. En aquellos pacientes con control de esfínter el diagnóstico de disfunción vésico-intestinal estuvo presente en 90% de los casos. El 44% de los pacientes a quienes se les realizó cintigrama renal DMSA tardío presentaron cicatriz renal. Conclusiones: El absceso renal en esta serie se presentó principalmente con fiebre persistente pese al tratamiento, requiriendo terapia antibiótica prolongada, y rara vez siendo necesario el drenaje quirúrgico. Sugerimos realizar estudio destinados a detectar factores modificables, como reflujo vésico-ureteral en pacientes sin control de esfínter, disfunción vésicointestinal en pacientes con continencia, y búsqueda activa de secuelas parenquimatosas renales.
Insuficiencia Intestinal Pediátrica, 10 años de experiencia en una Unidad de Cuidados Especializados
Authors: Wong Lam Carolina , Rosales Landero Nicole , Zamora Reyes Felipe , Reyes Espejo Bárbara , Guardia Borbonet Sylvia
Published: April 2022

La definición de Insuficiencia Intestinal (II) incluye la reducción de masa intestinal funcional y requerimiento de nutrición parenteral (NP) prolongada para lograr el desarrollo y crecimiento en la niñez. Objetivo: Evaluar la experiencia de una Unidad especializada en pacientes pediátricos con II, describiendo las características clínicas de aquellos admitidos desde noviembre 2009 a diciembre 2019. Pacientes y Método: Revisión del registro clínico de 24 casos que cumplieron los criterios de inclusión. Se recolectaron las siguientes variables: sexo, antecedentes neonatales, edad de ingreso, unidad de procedencia, diagnóstico antropométrico de ingreso, causa de insuficiencia intestinal, tiempo de hospitalización, edad de egreso de la unidad, datos antropométricos al egreso y dependencia de nutrición parenteral al alta. En aquellos pacientes con diagnóstico de Síndrome Intestino Corto (SIC) se identificó la causa de la resección intestinal y las características del remanente intestinal: clasificación anatómica, longitud de remanente (definiendo ultracorto como < 25 cm), presencia de válvula ileocecal y características del colon. Resultados: la mediana de edad al ingreso fue de 7,8 meses. Diecisiete casos eran prematuros. Etiología de la II: 10 pacientes con SIC, 6 casos de Neuromiopatía intestinal (NM), 7 pacientes con SIC asociado a NM y 1 caso Linfangiectasia intestinal. En la etiología de SIC encontrada en este grupo, la atresia intestinal con 8 casos y la enterocolitis necrotizante(ECN) 9 casos, fueron las causas principales en similar proporción. Ocho pacientes no tenían Válvula ileocecal (VIC). Según clasificación anatómica: 1 era tipo I, 8 tipo II y 8 tipo III. Por longitud intestinal 3 eran ultracortos, además de tipo II; en aquellos con remanente > 40 cm, 7 eran tipo III. El promedio global de estadía hospitalaria fue 456 días. Se logró autonomía enteral en 16 pacientes y 8 casos requirieron NP Domiciliaria. Conclusiones: La II requiere de soporte vital: NP y hospitalización prolongada. Su principal causa es el SIC secundario a atresia intestinal congénita y enterocolitis necrotizante. No obstante, la alta frecuencia de NM encontrada puede atribuirse al protocolo local de análisis. La mayoría de nuestros pacientes presentaban factores pronósticos desfavorables, sin embargo, el manejo por el equipo especializado permitió lograr autonomía enteral en 66,7% de los casos.
Primary ovarian hydatid cysts: A case series of two cases
Authors: Mehta Shradha , Mehta Bhavana , Shah Sandip , Vyas Sanjay , Sharma Raksha , Agarwal Saifali , RAO MANDAVA V
Published: April 2022

Hydatid disease is caused by the adult and the larval stage of tapeworms belonging to the Echinococcus species. The major sites of its infection are the liver and lungs. Rarely, it affects the pelvic region including the ovary, accounting for 0.2–2.25%. The primary ovarian site is a rare finding. We report here a case series of two cases with hydatid cysts as the left ovarian and tubo-ovarian masses. In case 1, a 30-year-old woman complained about lower abdominal pain with swelling and had a 7-month-old child and amenorrhea. Ultrasonographic report exhibited multiple cysts in the ovary. In case 2, a 23-year-old female was having primary left ovarian mass and clinically reported an ovarian dermoid tumor after ultrasound scan and had abdominal lump with pain. Her vital indices were normal. The biopsy was sent for further investigation.
Unusual Case of isolated post-styloid Parapharyngeal Space metastasis in a treated case of Carcinoma Supraglottis: A case Report and Review of literature
Authors: Panbude Sushil N. , Vaidya Abhishek , Pangarkar Meena A. , Juvekar Shashikant L.
Published: April 2022

Squamous cell carcinoma of supraglottis is common head and neck malignancy, comprising of 30% of laryngeal carcinoma. Supraglottic carcinoma commonly metastasizes to the level II, III and IV cervical nodes and distant metastases are uncommon. Delayed local and regional recurrences are known, local recurrence being more common. We report a case of carcinoma supraglottis with advanced locoregional disease at initial presentation and treated with neoadjuvant chemotherapy followed by chemo-radiotherapy with complete response on post treatment PET-CT scan. Surveillance PET-CT showed an isolated lesion in left post-styloid PPS where neurogenic tumors are more common and isolated nodal metastasis is unusual. We did ultrasound guided FNAC and cytology confirmed presence of metastatic poorly differentiated carcinoma.
ЕКОЛОГІЧНА БЕЗПЕКА СУЧАСНИХ ДЕРЖАВ В УМОВАХ ГЛОБАЛЬНИХ ВИКЛИКІВ І ЗАГРОЗ
Authors: Радченко Оксана Олександрівна
Published: April 2022

Мета роботи. У статті пропонується розгляд проблематики порушення природного балансу життєдіяльності ноосфери Землі та спричиненого цим наростання глобальних екологічних викликів, які стоять перед системами публічного управління національних держав та міжнародною спільнотою в цілому.Методологія. Методологічним інструментарієм проведеної розвідки є кейс-стаді виконання Указу Президента України «Про рішення Ради національної безпеки і оборони України від 23 березня 2021 року «Про виклики і загрози національній безпеці України в екологічній сфері та першочергові заходи щодо їх нейтралізації».Наукова новизна. Обґрунтовано, що ноосфера Землі на початку третього тисячоліття піддається тиску значної кількості глобальних викликів і загроз, які все більше виходять на передній план національної безпеки сучасних держав та екологічної безпеки усього людства. Проаналізовано стан реалізації заходів щодо протидії загрозам екологічній безпеці в Україні, який засвідчив, що лише незначна частина передбачених президентським указом першочергових заходів щодо забезпечення екологічної безпеки і підтримання екологічної рівноваги на території України виявилася вчасно виконаною в повному обсязі.Висновки. Зроблено висновок, що турбота про збереження природного середовища нашої життєдіяльності все більше виходить на передній план проблематики розвитку людської цивілізації та – врешті-решт – самого її існування. І одним з найголовніших напрямків діяльності усіх національних урядів має стати нова державна екологічна політика, яка функціонально покликана забезпечити досягнення конституційно-гарантованого рівня екологічної безпеки та безпеки життєдіяльності людини й суспільства через формування необхідних для цього політичних, економічних та соціальних умов, а також через проактивну протидію глобальним екологічним загрозам.
РОЗБУДОВА СИСТЕМИ ОРГАНІЗАЦІЙНОГО НАВЧАННЯ У ЗАКЛАДІ ВИЩОЇ ОСВІТИ
Authors: Семенець-Орлова Інна Андріївна , Храпатий Сергій Вікторович
Published: April 2022

Мета роботи. У статті проаналізовано сутність концепції організаційного розвитку, здійснено екстраполяцію основних її категорій у галузь вітчизняної вищої освіти. Через призму функціонального навантаження компонентів організаційного розвитку у реалізації стратегічних планів розвитку закладів вищої освіти визначено основні інструменти практичної реалізації концепції організаційного розвитку, що можуть бути використані у системі управління сучасним університетом.Методологія. Зростаючий запит на ініціативність, креативність, нестандартний підхід до проєктних активностей, емоційну стійкість, високу мотивацію досягнень, орієнтацію на майбутнє, оригінальне застосування спеціальних знань у вирішенні професійних завдань, стійкий характер продуктивності спілкування у діяльності сучасного викладача інноваційного університету визначає потребу особливих технологій підтримки його безперервного професійного вдосконалення з боку адміністрації закладу. Відповідальність керівників усіх рівнів за управління людськими ресурсами, підтримка новаторства у співробітників є викликом для управлінської діяльності у сучасному університеті.Наукова новизна. Забезпечення підготовки та впровадження освітніх змін на різних рівнях освітньої системи можливе завдяки створенню або освоєнню нової практики освіти. Це – нелінійні ситуації відкритого діалогу, прямого та зворотного зв’язків, солідарної освітньої пригоди, занурення в один самоузгоджений темп освіти. Це також ситуації пробудження власних сил і здібностей, відкриття себе, співробітництва із самим собою та іншими людьми, що допомагає з точки зору інноваційних практик оптимізувати плани, програми, рішення, загалом усю систему управління освітнім процесом у закладі.Висновки. Новітні підходи до забезпечення організаційного навчання через спільну діяльність викладачів, студентів, адміністрації та інших співробітників закладу все частіше розглядаються як частина концепції організаційного розвитку університетів.
МОДЕРНІЗАЦІЯ МОДЕЛІ ПУБЛІЧНОГО УПРАВЛІННЯ В МІНІСТЕРСТВІ ОСВІТИ І НАУКИ УКРАЇНИ
Authors: Хмелюк Віта Степанівна
Published: April 2022

Мета роботи. Публічно-управлінський прогрес суспільства потребує змін, пов’язаних із формуванням нової якості структури та функцій суспільних відносин. Модернізація включає у себе глобальні процеси, що відбуваються в усіх сферах життєдіяльності суспільства, які визначають його рівень готовності та здатності до еволюції. Метою дослідження є роз- криття механізмів модернізації моделі публічного управління Міністерства освіти і науки України. Методологія. Щоб досягнути мети дослідження, в роботі послідовно застосовуються три основні методологічні прийоми: неоінституціональний підхід, структурно-функціональний аналіз і системний підхід. Використання неоінституціонального підходу дозволяє дійти висновку, що в українському суспільстві наявні інституційні передумови для модернізації моделі публічного управління на основі теорії суспільного вибору. Модернізаційний розвиток інститутів при цьому представлено як свідомий вибір акторів змін в управлінській сфері. Завдяки структурно-функціональному аналізу стає можливим виокремлення складників публічного управління та їх функціональної спрямованості. Модернізація моделі публічного управління центрального органу виконавчої влади стосується не стільки існування деяких можливостей перетворення, скільки якості отримуваних освітніх послуг, тобто характеру функціонування певних інститутів, органів і структур. Використання системного підходу дозволяє розглянути два комплекси модернізаційних змін: у МОН як цілісну сукупність публічно-управлінських процесів, і в КМУ, який спрямовує та координує діяльність МОН. Наукова новизна. Дослідження характеризується двома основними положеннями науково-дослідницької новизни: з’ясовано інституційні передумови модернізації моделі публічного управління центральних органів виконавчої влади, а також окреслено публічно-управлінську модель ефективного функціонування МОН України. Висновки. Модернізація моделі публічного управління МОН уможливлюється у разі врахування опти- мізації інституційного та функціонального складників, а також завдяки вдосконаленню характеру функціонування Міністерства.
Development of Temperature and pH Responsive Smart Cotton Fabrics by P(NIPAM–co-MAM) Copolymer Finishing
Authors: DEMİRBAĞ GENÇ Sena , ALAY AKSOY Sennur
Published: April 2022

In this study, fabrication of dual responsive smart polymer and cotton fabrics with thermo-responsive and pH responsive properties was aimed. For this aim, poly(N-isopropylacrylamide-co-methacrylamide) P(NIPAM-co-MAM) copolymers containing different ratio of NIPAM/MAM monomers were synthesized. Analysis results showed that the copolymers were synthesized successfully by free radical addition polymerization method and their LCST values ranges from 33°C to 41°C. A selected sample of the synthesized copolymers was applied to fabric via double-bath impregnation method and thermo-responsive wetting property of the fabric was examined via wetting time and water uptake tests, contact angle measurement. The test results indicated that hydrophilic character of the fabric changed to the hydrophobic character reversibly depending on change in temperature. The fabric could manage water vapor permeability via changing pore size as well as their hydrophilic character depending on temperature. Besides, it was concluded that the fabrics had strong antibacterial activity against S.aureus bacteria.
A importância do serviço humanizado na urgência e emergência
Authors: Sousa Marinalva Valença de , Sandim Lucíola Silva
Published: April 2022

No atual contexto da área de saúde pública, a humanização é um tema que vem se destacando, sendo abordada constantemente, como tema acentuado e como assistência para a melhoria do cuidado e para a consolidação dos princípios e valores do Sistema Único de Saúde (SUS). Objetivo: Descrever a importância da assistência humanizada de enfermagem prestada aos pacientes em situações críticas de emergência. Método: Trata-se de uma revisão da literatura. Para levantamento dos artigos foi realizado busca online na Biblioteca Virtual de Saúde (BVS), usando os seguintes descritores de saúde (Decs): Enfermagem, UTI, Humanização, Urgência e Emergência. Resultados: O ato de humanização é essencial para uma prática bela, no qual deve ser pautado segundo os valores éticos, ainda que a mesma lide com situações degradantes, dolorosas e tristes na natureza humana, como o sofrimento, a deterioração e a morte. Neste contexto, refere-se à possibilidade de admitir uma posição ética de respeito ao outro e reconhecimento dos limites. Assim, se atentando aos pequenos gestos, atitudes e expressões, toda a equipe pode aplicar a teoria na prática, conseguindo agir de maneira humanizada e, por conseguinte, com respeito. Conclusões: Através do estudo constatou-se que a eficiência de uma boa abordagem realizada pelo enfermeiro, principalmente aos que atuam na unidade de urgência e emergência, ajuda a instituir o diagnóstico precoce e o tratamento oportuno e seguro para o paciente.
Mengangkat Potensi Jamu Tradisional sebagai Alternatif Usaha di Era Digital
Authors: Purwanto Nuri
Published: April 2022

Raising the potential of traditional herbal medicine as an alternative to business in the digital era is the theme chosen for preservation, because Indonesia's potential is rich in natural products that can be used for medicinal plants, especially with the COVID-19 pandemic, the women of PKK Tambakrejo take advantage of this opportunity by utilizing plants. ginger as a business opportunity, the implementation of the activity is carried out for three days with materials taught about, market research, product manufacturing practices to sales, the method used is using seminars and workshops, the first day is providing material in the form of seminars, the second day is a workshop, namely the practice of making products. and the third day of sales, the service process goes according to expectations.
Pengembangan Keterampilan Santri melalui Pelatihan Desain Grafis di Syarif Hidayatullah Cyber Pesantren
Authors: Hasanah Nurus Sariroh Al , Fanani Moh Zainal
Published: April 2022

Pesantren is a place to learn about religious knowledge, in the modern era students not only master religious knowledge but other skills must be mastered such as graphic design. These skills and abilities will be needed by students in the future, therefore one solution in helping these problems is the holding of graphic design training aimed at new students of Syarif Hidayatullah Cyber ​​Islamic Boarding School. The graphic design training activities carried out were focused on twibbon design training using Corel Draw X7. The implementation stage is the delivery of material, practice, and the last evaluation. The results achieved during the training can be seen from the enthusiasm of the students in participating in the training.