bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparative Analysis of Communication Strategies in Managing the COVID-19 Pandemic Crisis: Lessons from New Zealand and Sweden, Considering Population Differences
Authors: Cati Matteo Maria
Published: January 2025

Amid the unprecedented challenges posed by the COVID-19 pandemic, effective communication emerged as a linchpin in navigating the crisis and shaping public responses. This article conducts a meticulous comparative analysis of the communication strategies employed by New Zealand and Sweden, countries renowned for their distinctive approaches, while also acknowledging the significant variance in their population sizes. Leveraging empirical data, scholarly literature, and per capita normalization techniques, we delve into the impact of these strategies on critical metrics such as death tolls, economic outcomes, and social cohesion. Results indicate that clear and consistent communication contributed to lower per capita mortality in New Zealand. Meanwhile, tailoring public health messaging to sociocultural contexts and balancing individualism with collectivism appears vitally important. The findings highlight valuable lessons for crisis communication strategies suitable across diverse population settings.
"A backbone pain": 61-year-old Female with Acute Aortic Dissection Stanford Type B
Authors: Pari Laoura , Soteriou Marinos , Mitselos Lambros , Lambrinou Ekaterini
Published: January 2025

Introduction: In Europe, Cardiovascular Diseases (CVDs) remains the most common cause of morbidity and mortality, with 49% of deaths in women and 40% of deaths in men. Women have a higher risk of CVDs mortality, worse prognosis, and outcomes, major cardiovascular events, are undertreated, and have a lower rate of diagnostic angiograms and interventional procedures, compared to men.

Case Summary: A 61-year-old white female, presented to the Emergency Department (ED) with chief complaints of sudden bone pain and a headache. She had been evaluated but discharged without further investigation from another ED, because of the symptoms she reported. She has a history of smoking for 30 years. Her family history included sudden death for both parents, with the symptomatology of an aneurysm. She never had a cardiovascular (CV) assessment before or any CV symptoms. Upon triage, the pain was located in the upper back and extended down the back. She characterized it as ‘bone pain’ (skeletal pain). Vital signs revealed high Blood Pressure (BP) [216/97] mmHg. Her initial laboratory investigation revealed D-dimers level 1.01μg/ml with an upper limit of normal <0.50μg/ml. Urgent Computerized Tomography Angiography of whole aorta with IV contrast was performed and a diagnosis of Aortic Dissection Stanford Type B was given. The patient was admitted to the ICU for close hemodynamic monitoring and medical therapy, BP control, and pain management. The patient was monitored for 19 days without any complications. There were no indications for surgical intervention between admission and discharge, based on the latest guidelines.

Discussion: The presented clinical case is an example of lack of adequate recognition and assessment by health professionals, but also of inadequate prevention and delay of presentation to medical care by the patient due to misconception. This must drive the community of cardiology to implement changes in prevention, diagnosis, intervention, and management for women, and provide education and training in early recognition and management of CVDs in the medical community, taking into consideration the sex and gender differences.
Relapsing Polychondritis: A ‘Revival’ in the American Indian/Alaska Native population
Authors: Kaushik Prashant , Mach Kaylee I , Alexander Caleb S
Published: January 2025

Relapsing polychondritis (RPC) is a systemic inflammatory immune-mediated rheumatic disease (SIIRD) primarily affecting the cartilaginous structures within organs such as the ear, nose, joints, tracheobronchial tree, and cardiovascular system but it can also impact organs that are not primarily cartilage-based, such as skin, blood vessels, eyes and inner ear. Here we present 3 cases of RPC as an SIIRD from the American Indian/Alaska Native (AI/AN) population of the Cherokee Nation (CN), Oklahoma. After a single-case of RPC in a Zuni Indian patient published in 1971, to the best of our knowledge, this is the first publication of a series of RPC in the AI/AN population.
New Medication to Treat Speech Delay
Authors: Mohammadimoshganbar Ali , Mostafavi Gholamreza , Hoorandghadim Amin
Published: January 2025

Background: Delay in language development, social communication, play skills, and behavior in kids can be attributed to a variety of factors. One common cause is genetic predisposition [1], as children with a family history of language or developmental delays are more likely to experience similar challenges themselves. Additionally, neurological factors such as brain injury or abnormalities such as Seizures can impact a child's ability to develop language and social skills [2,3,4].

The most common and effective treatments available include speech therapy, social skills training, occupational therapy and play therapy, which help children improve their abilities. However, none of these treatments are definitive.

Case Presentation: Here, we present a child who is currently 8 years old. At the age of three years and one month, Soren is a boy and he was evaluated in a clinic in Australia due to problems such as inability to establish verbal communication. The results of the evaluation showed concerns about the development of speech skills, social communication, behavioral skills, and playing. At the age of three years and one month, he was largely non-verbal and had significant speech impairments. Consulting and evaluation led to the conclusion that he needed speech therapy, occupational therapy, play therapy, and psychological counseling. Additionally, Ritalin medication was prescribed for him .According to his mother's statement, it did not have a good effect on him and only caused a loss of appetite followed by overeating and obesity in the child. In this case, we started a new medication for him once a day. We began this medication in December 2022, and the results were remarkable. He is now able to speak and form sentences. Let's talk a little bit about Soren's progress.

Conclusion: The inability to speak in children can have various causes such as genetic factors, brain impairments, etc. We examined a child who had experienced a lack of progress in speech and behavioral skills, and had also suffered from seizures at the age of fifteen months. A new medication was prescribed for him, which led to a significant improvement in his verbal communication and considerable progress in his behavioral skills. We believe that this medication has been able to activate more parts of the brain related to speech. Furthermore, with the use of this medication, it triggered the rearrangement of the neuronal DNA related to speech, enabling the child to speak.
Bone Health Following Sleeve Gastrectomy versus Roux-en-Y Gastric Bypass Surgery
Authors: Abou-Basha Ahmed B , Zidan Walid , Emam Omnia , Abdelfattah Fatma , Bakry Radwa A
Published: January 2025

Introduction: Bariatric surgery may have detrimental effects on bone health. We investigated the long-term effects of bariatric surgery on bone health to delineate whether they differed by procedure type.

Methods: The records of patients who had undergone either sleeve gastrectomy (SG) or Roux-en-Y Gastric Bypass (RYGB) surgery with a follow up period of 2 years were reviewed. Comparison was made between blood assays (vitamin D, parathormone, calcium, phosphate and magnesium) and aerial bone mineral density (aBMD) measured at baseline with measurements made at 6, 12, 18 and 24 months post-operatively. History of fractures was also recorded.

Results: There were 1309 in the SG group and 1132 patients in the RYGB group. There was a gradual decrease in vitamin D, calcium, phosphate and magnesium and increase in parathormone levels peaking at 18 months in both groups (P<0.05). There was also reduction in aBMD over time being greater at 24 months and most marked in the total hip and full body measures (p<0.05). This correlated to amount of weight loss. All changes were more in RYGB (p<0.05) where there was also a higher number of post-operative fractures (p<0.05).

Conclusion: Bariatric surgery is associated with gradual decline in bone health and increased fracture risk peaking at 18 months after surgery. This effect is more prominent with RYGB (combined restrictive and malabsorptive) procedures as opposed to SG (restrictive only) surgeries. It is imperative to counsel patients about increased bone fragility and fracture risk prior to making the choice of bariatric surgery.
Взаємозв’язок між стадіями розвитку організації і рівнем культури безпеки праці
Authors: Tsopa Vitaly , Bolibrykh Boris , Kolesnik Valery , Cheberyachko Serhii , Deryugin Oleg , Sharovatova Olena
Published: January 2025

Мета роботи: виявити взаємозв’язок між стадіями розвитку організації і рівнем культури безпеки праці працівників.
Метод дослідження: модель розвитку організації Іцхака Адізеса та модель кривої Бредлі.
Результати дослідження: Запропоновано рівень культури безпеки праці в організації за кривою Бредлі. Побудовано матрицю впливів керівника, фахівця з безпеки праці, самоусвідомлення та взаємодопомоги, самих працівників на виконання вимог в системі управління безпекою праці та здоров’я працівників, яка дозволила виявити взаємозв’язок коефіцієнтів  виконання (не виконання) вимог систем управління безпекою праці та здоров’я працівників і відповідного рівня культури безпеки.
Практична цінність дослідження: Побудовано матрицю для визначення рівнів культури безпеки праці по моделі  кривої Бредлі з урахуванням ставлення керівника, фахівця з безпеки праці та працівників до виконання вимог безпеки праці і здоров’я працівників.
Обґрунтування показників визначення військових втрат, завданих внаслідок бойових дій
Authors: Kosaretskyi Yevhenii
Published: January 2025

Мета роботи: обґрунтування необхідності введення додаткових показників визначення військових втрат, заподіяних внаслідок воєнних дій.
Метод дослідження: аналітичний метод, спостереження та формалізація.
Результати дослідження: Проведено дослідження та запропоновано формалізацію витрат, пов’язаних з реабілітацією військовослужбовців, підготовкою військових фахівців для сил оборони. Наведені кількісні показники завданої шкоди навколишньому середовищу на об’єктах Міністерства оборони України.
Теоретична цінність дослідження: Розглянуті показники визначення військових витрат та втрат дають можливість підвищити ефективність нормативного-правового забезпечення з питань оцінки збитків та шкоди, спричинених збройною агресією.
Цінність дослідження: Введення додаткових показників визначення військових втрат дає можливість отримати більш повну та достовірну інформацію щодо структури заподіяної шкоди під час формування реєстру військових збитків.
Майбутні дослідження: Подальші дослідження повинні бути спрямовані на  ревізію показників військових витрат (втрат) та удосконалення механізмів оцінки збитків в системі Міноборони.
Comparative analysis of cybersecurity in leading cloud platforms based on the NIST framework
Authors: Molnar Vitalii , Sabodashko Dmytro
Published: January 2025

Abstract
Purpose: To examine the cybersecurity capabilities of three leading cloud platforms—AWS, Azure, and GCP—according to the five core functions of the NIST Cybersecurity Framework: identify, protect, detect, respond, and recover.
Method: A comparative approach was used, covering the analysis of the tools and services of each platform for the implementation of NIST functions.
Findings: The analysis demonstrated the strengths and weaknesses of AWS, Azure, and GCP in terms of identity, protection, detection, response, and recovery capabilities, highlighting the most effective tools for each.
Theoretical implications: The study deepens the understanding of cybersecurity strategies based on the NIST framework and can serve as a basis for further research in the direction of optimizing protection in cloud environments.
Practical implications: The obtained results provide valuable recommendations for improving cloud security practices through informed choice of cloud services and security strategies.
Value: The study offers a structured approach to assessing the cybersecurity of cloud platforms, highlighting each provider's ability to address different aspects of cybersecurity.
Future research: Future research may focus on the impact of emerging technologies such as artificial intelligence and machine learning on improving the effectiveness of cybersecurity in cloud environments.
Paper type: Conceptual research.
 
Key words: cloud computing, cloud services, cloud security, cybersecurity, NIST framework
Дослідження загроз безпеки великих мовних моделей за допомогою автоматизованих інструментів
Authors: Kolchenko Viktor , Khoma Volodymyr , Sabodashko Dmytro , Perepelytsia Pavlo
Published: January 2025

Мета роботи: огляд та аналіз відомих підходів виявлення вразливостей великих мовних моделей (ВММ), розробка архітектури автоматизованої системи для тестування вразливостей, створення набору підказок для виконання практичного тестування ВММ для оцінювання їх безпеки..
Результати дослідження: дослідження показало, що автоматизована система  з використанням утиліти Garak, може ефективно виявляти та запобігати атакам на великі мовні моделі. Застосування таких систем значно підвищує рівень безпеки мовних моделей.
Теоретична цінність дослідження: у статті представлено новий підхід до забезпечення безпеки мовних моделей шляхом автоматизації тестування вразливостей. Це доповнює існуючі теоретичні підходи у сфері кібербезпеки та моделювання.
Практична цінність дослідження: науковці та розробники можуть використовувати результати дослідження для створення безпечніших мовних моделей, а також для вдосконалення алгоритмів, які запобігають маніпуляціям і зловживанням.
Цінність дослідження: стаття пропонує нові технологічні рішення, зокрема впровадження автоматизованої системи на основі утиліти Garak, що дозволяє покращити безпеку, стійкість і ефективність мовних моделей. Це має значення для подальшого розвитку галузі штучного інтелекту та кібербезпеки.
Майбутні дослідження: результати можуть змінюватися залежно від конкретних архітектур мовних моделей або видів атак. Майбутні дослідження доцільно зосередити на вдосконаленні алгоритмів для виявлення нових видів атак та підвищенні ефективності автоматизованої системи в умовах змінних загроз.
Model Pembelajaran Pasti Aksi Hanifida dan Profesionalisme Guru Pendidikan Agama Islam
Authors: Makhfudhoh Nurul , Idawati Khoirotul
Published: January 2025

This study aims to describe the professionalism of Islamic Religious Education (PAI) teachers through innovative learning models (Hanifida Action Definite Learning Model). The type of research used is a literature study, where the researcher utilizes various relevant literature to obtain research data in the form of descriptions. Based on the results of the literature review, the researcher concluded that the Hanifida Action Definite Learning Model is one of the approaches in Islamic Religious Education that focuses on the implementation of real actions in learning. This approach emphasizes the understanding and application of religious values in daily life, not just the mastery of theory. By implementing the Hanifida Action Definite Learning Model, teachers can develop their professionalism in the form of a deep understanding of Islamic religious values and how to apply them in daily life. This encourages teachers to continue to improve their professional competence through various training and further studies. Thus, the Hanifida Action Definite Learning Model has the potential to improve the professionalism of PAI teachers by encouraging teachers to continue learning, adapting, and applying relevant and effective teaching approaches in teaching Islamic religious values
Manajemen Sumber Daya Manusia (SDM) Ma’had Aly di Dayah Babussalam Al Hanafiyyah
Authors: Safwan Muhammad , Siregar Zulfikar Ali Buto , Mukhtasar Mukhtasar
Published: January 2025

To realize the tridarma of Ma'had Aly, it is necessary to implement good HR management in the field of management, because the success of HR in managing Ma'had Aly will guarantee the quality of Ma'had Aly's output. This research aims to find out the process of HR procurement and development in Ma'had Aly Babussalam Al Hanafiyyah. This research is a qualitative research with a case study approach. Data collection techniques were carried out through observation, interview and documentation. The results showed that: First, the recruitment process in Ma'had Aly Babussalam Al Hanafiyyah is not fully in line with the concept of recruitment in other formal education because there is no significant selection process and no new employee orientation as in the modern management concept. The recruitment of internal dayah and alumni recruitment systems is considered more affordable. Internal human resources are considered more effective in supervising and nurturing mahasantri at all times. HR placement is based on the teacher's exceptional ability to understand the Yellow Book and formal educational qualifications are not a benchmark for placement. Second, human resource development is carried out through skill development training, continuation of formal education, independent learning development. Skill development training at Ma'had Aly Babussalam Al Hanafiyyah gave birth to lecturers who were skilled in scientific journals and books, development through formal education is carried out by continuing the lecturer's postgraduate program studies which are considered to develop conceptual skills for lecturers.
Implementasi Nilai-nilai Islam dalam Praktik Rekrutmen dan Seleksi Dosen di Sekolah Tinggi Islam Sunniyyah Selo Grobogan
Authors: Rahayu Sucik , Wangsanata Susana Aditya , Mareta Mira
Published: January 2025

Modern higher education plays a role in the development of global society with universities as centers of learning and technology that facilitates broad access to education. Sunniyyah Selo Islamic College Grobogan integrates Islamic values in lecturer recruitment to ensure academic competence and moral integrity, creating an academic environment that supports the development of Islamic character in students. This research aims to identify the application of Islamic values in the recruitment and selection practices of lecturers at Sunniyyah Selo Islamic College. The analysis was carried out using a qualitative descriptive analysis method. The results of this research show that the implementation of Islamic values in the recruitment and selection of lecturers at Sunniyyah Selo Islamic College emphasizes academic, moral and spiritual criteria with transparency and justice. This strategy includes the formation of a committed recruitment team, selection criteria based on Islamic values, and comprehensive selection methods, as well as collaboration with religious institutions. These steps create a fair and transparent academic environment, strengthen STISS's identity as a credible Islamic education institution, and contribute to the sustainable development of Islamic education.
Pengaruh Struktur Organisasi dan Budaya Kerja Terhadap Kinerja Sekolah di SMP Negeri Kecamatan Kepahiang
Authors: Syamsir Syamsir , Adekamisti Revi , Riyan Riyan , Yanto Murni , Ifnaldi Ifnaldi , Azwar Beni
Published: January 2025

This study investigates the impact of organizational structure, work culture, and managerial processes on the performance of junior high schools (SMP) in Kepahiang District. Recognizing that school performance goes beyond academic achievement to encompass effective organizational management, the research emphasizes the role of adaptive structures, collaborative work cultures, and participative management systems. Using a qualitative case study approach, data were gathered through in-depth interviews, observations, and analysis of school documents, including performance reports and strategic plans. Findings indicate that flexible organizational structures improve communication pathways and clarify roles, which supports efficient task completion. Schools with a collaborative work culture benefit from enhanced staff interactions, innovation, and shared goal alignment, positively influencing both teaching quality and student outcomes. Additionally, participative management processes that involve staff in decision-making foster a sense of ownership and boost motivation, thereby enhancing overall school effectiveness. This study suggests that a combination of adaptive structure, collaborative culture, and participative management significantly strengthens school performance. Future research should explore the influence of school leadership and professional development on educational outcomes and examine practical approaches to support schools in meeting evolving educational demands
Concerns and Challenges of Women about Reproductive Health During Pandemic
Authors: Yıldız Hatice
Published: January 2025

Introduction: Women experience disruptions in reproductive health services, issues, challenges, and worries in this setting as they attempt to manage the Covid-19 epidemic.

Objective: The aim of this study was to determine women’s concerns and difficulties encountered regarding reproductive health during the pandemic process.

Materials and Methods: The study has a descriptive, cross-sectional design. This study was carried out among 237 women between the ages of 18-49. A survey form consisting of 26 structured questions was used to collect the data. The data were analyzed using the Statistical Package for the Social Sciences Version (SPSS) 22.00 program.

Result: Women had experienced reproductive health problems were 33.1%, those who needed reproductive health services were 34.5%, and those who had difficulty accessing health services were 30.0%. The use of contraceptive methods was 26.0%, the rate of pregnancy experience was 1.6% and 97.0% of the women stated they did not want to get pregnant during pandemic period. Women’s fear/avoidance of pregnancy level was 4.8±3.4 and the level of fear/avoidance of pregnancy was significantly increasing as anxiety of getting sick with the coronavirus and that this virus would harm their and their partner’s fertility increased (p<0.01).

Conclusion: It can be said that coronavirus and the pandemic process negatively affect women’s desire for pregnancy, thoughts about their and their partner’s fertility, increase problems/concerns about reproductive health, and their need for services has increased in this period, but they’ve had difficulties.
ROOTS PROGRAM UTILITY; FORMING AN ANTI BULLYING PREVENTION AGENT IN MADRASAH
Authors: Junaedi Achmad
Published: January 2025

This study aimed to determine the efforts of teachers to apply interactional teaching style as an interdiscipliner approach to identify student learning characteristics. This research included phenomenological research with a qualitative approach. The research location was conducted at MTs. NU, Kraksaan District, Probolinggo. Data collection techniques were carried out through a process of observation, in-depth interviews with 4 informants, and documentation. The data analysis technique used the Miles and Huberman Interactive Model with data reduction activities, data presentation, and drawing conclusions. Data validity with source and technique triangulation process. The process undertaken in the Roots program included several stages, namely conducting surveys, selecting agents of change, providing training to agents of change, carrying out demonstrations or social campaigns in the madrasah environment, and evaluating the Roots program. Of course the Roots program has been carried out according to the plan and systematic program of activities and of course the agents of change can synergize themselves as actors driving students' understanding and concern about stop-bullying in the madrasah environment. The implications of the research illustrated that collaboration between madrasahs, facilitators, agents of change, and students is established in a supportive manner and upholds the value of tolerance.
INTERACTIVE POWER POINT-BASED TEAM GAME TOURNAMENT LEARNING TO INCREASE STUDENTS’ INTEREST IN ISLAMIC EDUCATION
Authors: Rizqiyah Afi , Affa Gilbrania , Maimunah Mas Hanik Nur , Uroidli Ali
Published: January 2025

This study examined the implementation of an interactive PPT-based TGT learning model to increase student interest. This research was a Classroom Action Research conducted in class IX B SMP Islam As Sakinah Sidoarjo which consists of 22 students. This class was chosen as the research subject because it showed a lower learning interest in Islamic Educationsubjects compared to class IX A with the application of the same learning method. However, according to the Islamic Educationteacher, this class has greater potential if the students’ interest in learning can be improved. Primary data were collected through observation and questionnaires, then analyzed qualitatively and statistically descriptively. Supported by secondary data obtained through interviews and literature studies to find problems and ensure the availability of facilities, and find out student responses to the learning model applied. The results showed an increase in student interest from pre-action by 62% to 94% after implementing the interactive PPT-based TGT learning model. There was also an increase in the number of active students from 16 students to all students in the class (22 students). It can be concluded that the application of interactive PPT-based TGT learning methods can increase students’ interest in Islamic Education learning. Synergizing the TGT learning model with interactive PPT media is one of the right actions to increase student interest in learning. Teachers who find the problem of lack of student interest in learning can apply the TGT learning model by utilizing interactive PPT media as done in this study. In addition, this study can be a reference for further researchers who want to examine the implementation of TGT learning or interactive PPT media in learning.
INFLUENCE OF INTERNET ADDICTION ON ACADEMIC PERFORMANCE OF SENIOR SECONDARY SCHOOL STUDENTS OF ISLAMIC STUDIES
Authors: Ayuba Jibril Olaniyi , Abdullateef Lawal Abiola
Published: January 2025

The study examined the influence of internet addiction on academic performance of senior secondary school Islamic Studies students in Ilorin, Nigeria. The study adopted quantitative method of research design. Simple random sampling technique was used to select 150 senior secondary school students of Islamic Studies in Ilorin, Nigeria. An adapted questionnaire was used to elicit information from the respondents. Two research questions were raised and answered using Mean and Standard Deviation while PPMC was used to test formulated hypothesis at 0.05 level of significance. Findings from the study revealed that there is high level of internet addiction among senior secondary school students of Islamic studies in Ilorin, Nigeria. Also, the study revealed that there is significant relationship between internet addiction and students` academic performance among senior secondary school students in Ilorin, Nigeria. In line with the findings of the study, it is recommended that schools should organize seminars for students to use internet to enhance academic excellence. It was concluded that teachers and parents must work together to assist the students on effective usage of internet usage.
TATA KELOLA KOLABORASI MELALUI SEGORO BENING DAN CETING BUHARI DALAM PENANGANAN KASUS STUNTING DI YOGYAKARTA
Authors: Driatama Dyas Ayuda
Published: January 2025

Tujuan penelitian adalah untuk mengetahui faktor dominan determinan stunting, tata kelola kolaborasi yang dilakukan Pemerintah Kota Yogyakarta dalam menangani stunting, dan partisipasi masyarakat dalam bentuk gerakan masyarakat yang terbentuk dalam penanganan stunting di Kota Yogyakarta. Metode penelitian yang digunakan adalah metode penelitian kualitatif. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah dokumentasi dan wawancara. Hasil penelitan ini menjelaskan bahwa stunting menjadi salah satu permasalahan yang belum selesai di Kota Yogyakarta. Hal tersebut karena masih adanya kasus stunting yang tinggi di beberapa daerah kemantren di Kota Yogyakarta. Adapun faktor dominan determinan stunting adalah Ibu Hamil KEK (Kurang Energi Kronis) dan merokok. Tata kelola kolabarasi Pemerintah Kota Yogyakarta atau dalam hal ini adalah Dinas Kesehatan Kota Yogyakarta telah berkolaborasi dengan berbagai pihak baik dari sektor pemerintah, sektor akademisi, sektor usaha, serta sektor masyarakat madani. Sektor-sektor tersebut ikut terlibat dalam penanganan stunting yang berupa inovasi gerakan masyarakat yakni gerakan masyarakat Segoro Bening ( Semangat Gotong Royong Bebas Dari Stunting ) yang dipelopori oleh Pemerintah Kemantren Wirobrajan dan Ceting Buhari (Cegah Stunting 1000 Hari) yang dipelopori oleh Kemantren Gedongtengen. Selain adanya gerakan masyarakat, Pemerintah Kota Yogyakarta juga telah membentuk TPPS (Tim Percepatan Penurunan Stunting) yang melakukan sesi diskusi dua minggu sekali antara beberapa instansi terkait. Meskipun begitu, masih terdapat beberapa kendala dalam penanganan tersebut. Kendala yang dimaksud adalah terkadang masyarakat tidak disiplin dalam mengikuti arahan dari Dinas Kesehatan Kota Yogyakarta, serta kesalahpahaman komunikasi dalam implementasi di lapangan dalam penanganan stunting.
IMPLEMENTASI PERATURAN DAERAH NOMOR 15 TAHUN 2019 TENTANG DESA WISATA DI DESA SOMONGARI
Authors: Affiangit Tesar , Dewi Mutiar Fitri
Published: January 2025

ABSTRAK. Sebagai salah satu sektor unggulan, pariwisata perlu dikembangkan dengan serius supaya dapat berkontribusi nyata pada pendapatan negara dan daerah yang pada akhirnya dapat membantu menyejahterakan masyarakat. Tren saat ini yaitu pengembangan desa wisata yang banyak dilakukan di berbagai daerah di Indonesia termasuk di Desa Somongari Kecamatan Kaligesing Kabupaten Purworejo Jawa Tengah. Dalam penelitian ini, peneliti mencoba mendeskripsikan implementasi Peraturan Daerah Nomor 15 Tahun 2019 tentang Desa Wisata serta mengidentifikasi faktor pendukung dan penghambat serta upaya dalam mengatasi hambatan implementasi. Penelitian ini termasuk penelitian kualitatif dengan pendekatan deskriptif. Teori yang digunakan yaitu teori implementasi dari Van Meter & Van Horn (1975). Data dikumpulkan melalui in-depth interview, observasi, dan dokumentasi. Setelah dikumpulkan, data kemudian dianalisis dengan model analisis interaktif Miles, Huberman, Saldana (2014). Hasil penelitian menunjukkan implementasi kebijakan telah berjalan dengan baik yang didukung komitmen dan komunikasi yang baik dari apara pelaksana kebijakan dan masyarakat memiliki kesadaran tinggi dalam pengembangan desa wisata. Adapun yang menjadi faktor penghambat yaitu kurangnya pemahaman pelaksana kebijakan terhadap Peraturan Daerah Nomor 15 Tahun 2019 tentang Desa Wisata, sumber daya Pokdarwis yang belum memadai dan kompeten, serta pengelolaan dana desa yang belum optimal dan minimnya dukungan anggaran untuk pembangunan fasilitas penunjang.
 
Kata kunci: implementasi; kebijakan; pengembangan; pemerintah; desa wisata
Analisis Sanitasi Bandar Udara Fatmawati Soekarno Bengkulu
Authors: Angraini Wulan , Afriyanto Afriyanto , Wati Nopia , Febriawati Henni , Sarkawi Sarkawi , Rizal Achmad Faisal , Pratiwi Diyan
Published: January 2025

Bandar udara Fatmawati sebagai tempat keluar masuknya manusia dari berbagai destinasi perlu mendapatkan perhatian dalam aspek penciptaan lingkungan sehat guna melindungi pengguna bandar udara dari penyebaran penyakit dan gangguan kesehatan. Penelitian ini bertujuan untuk menganalisis kondisi sanitasi di Bandar Udara Fatmawati Soekarno Bengkulu dan telah mendapatkan izin dari Kantor Kesehatan Pelabuhan Kelas III Bengkulu dengan nomor 238/SKTMP/KKP-BKL/VIII/2021. Penelitian ini bersifat observasional deskriptif. Teknik pengumpulan data menggunakan pengukuran secara langsung dengan daftar observasi. Hasil penelitian mendapatkan skor kondisi sanitasi di Bandara Fatmawati Soekarno Bengkulu 6.900 (56,21%) sehingga dinyatakan tidak sehat. Upaya penyelenggaraan penyehatan lingkungan memperoleh nilai 54,21%, penataan sarana dan prasarana 56,44%, peningkatan PHBS 71,42%, peningkatan keselamatan dan kesehatan kerja 85,33%, keamanan dan ketertiban 80%, dan aspek kelembagaan 50,26%. Kondisi kesehatan lingkungan bandara, fasilitas, serta upaya kelembagaan dikategorikan tidak baik. Namun, upaya peningkatan perilaku hidup bersih dan sehat serta peningkatan keamanan dan ketertiban dikategorikan memenuhi syarat karena petugas di lingkungan luar bandara wajib menggunakan APD (alat pelindung diri).
Pengembangan Model Triase Berbasis Intervensi Cest (Caring, Edukasi dan Patient Safety) dalam Meningkatkan Kepuasan Pasien
Authors: Panjaitan Yunita , Haloho Maria Artaulina , Suryani Irma , Amalia Hilda
Published: January 2025

Pengetahuan dan pemahaman pasien dan keluarga terhadap sistem triase di instalasi gawat darurat (IGD) yang belum optimal dapat menimbulkan konflik karena anggapan kurang diperhatikan dan tidak diberikan tindakan yang pasti. Oleh karena itu, pengembangan model triase dengan intervensi aktif pemberian caring, edukasi dan patient safety dibutuhkan dalam pelayanan triase di IGD. Tujuan penelitian ini adalah untuk mengetahui pengaruh model triase berbasis intervensi caring, education, and patient safety (CEST) terhadap tingkat kepuasan pasien IGD di Rumah Sakit Hermina, Indonesia. Penelitian ini menggunakan pendekatan kuantitatif, desain true experiment dengan rancangan post-test only grup control design. Sampel dalam penelitian ini adalah 30 kelompok intervensi dan 30 kelompok kontrol yang dipilih dengan teknik simple random sampling. Uji statistik yang digunakan adalah independent t-test. Hasil penelitian ini menunjukkan bahwa terdapat perbedaan kepuasan pasien yang signifikan antara kelompok kontrol dengan kelompok intervensi. Rata-rata kelompok kontrol adalah 26,07 dan rata-rata kelompok intervensi adalah 29,70. P-value pengaruh pelaksanaan triase model CEST antara kelompok kontrol dan intervensi adalah 0,002 (< 0,05). Pengembangan model triase CEST dapat meningkatkan kepuasan pasien dengan cara memberikan rasa caring, edukasi dan penerapan keselamatan pasien di rumah sakit.
Pengaruh Senam Aerobik Low Impact dalam Menurunkan Tekanan Darah Penderita Hipertensi
Authors: Syavinka Zuan Nun Alea , Yuniartika Wachidah
Published: January 2025

Hipertensi merupakan masalah kesehatan global yang meningkat dan berisiko menyebabkan komplikasi serius seperti penyakit jantung, stroke, dan gagal ginjal. Kondisi ini seringkali diabaikan sehingga diperlukan strategi intervensi non-farmakologis yang mudah diakses seperti senam aerobik low impact. Penelitian ini bertujuan untuk mengeksplorasi dampak senam aerobik low impact terhadap penurunan tekanan darah pada pasien hipertensi. Penelitian ini menggunakan pendekatan kuantitatif dengan desain pra-eksperimental. Populasi penelitian terdiri dari 35 penderita hipertensi di wilayah kerja Puskesmas Baki dengan kriteria inklusi, yaitu: penderita hipertensi ringan dan sedang yang mampu melakukan aktivitas fisik dan tidak rutin mengonsumsi obat. Intervensi senam dilakukan selama 8 minggu dengan frekuensi 2-3 kali setiap minggunya dan durasi 15 menit setiap sesinya. Data yang diperoleh dianalisis menggunakan Wilcoxon signed-rank test, mendapatkan P value sebesar <0,001 untuk tekanan darah sistolik dan 0,001 untuk tekanan darah diastolik. Hasil analisis data ini mengindikasikan bahwa senam aerobik low impact berpengaruh dalam menurunkan hipertensi.
Herbicide resistance prediction: a mechanistic model vs. a random forest model
Authors: Richter Otto , Lepke Janin , Herrmann Johannes , Beffa Roland
Published: January 2025

Introduction

Herbicides are an important technology in the Integrated Weed Management (IWM) tool box aiming to control weeds in modern agriculture. Prediction tools to evaluate the risk of resistance evolution will greatly help to choose the best IWM strategy adapted to the local field situation. These comprise classical simulation models, mechanistic models (MMs), combining population dynamics and genetics, and recently artificial intelligence (AI) methods such as random forest. In this paper, both approaches are compared.

Materials and methods

Artificial data were generated by an MM and used as training dataset for a random forest classifier. Field history information was taken from two previous studies. The data include the field histories and resistance status of Alopecurus myosuroides of 98 fields from the Hohenlohe area in Germany and 131 from the Champagne area in France.

Results and discussion

With accuracies of approximately 80%, the results obtained by the random forest method applied to model-generated data and real field data, respectively, are well comparable. This concerns the ranking of prediction variables and the prediction of the resistance status of a real field and a “model field”. Predictions with model outcomes as training sets and, vice versa, predictions of a “model field” with real data as training sets and predictions by splitting of field data could be made with nearly the same accuracies.

Conclusion

Complementarity is shown between both approaches with the advantages of AI such as random forest to avoid approximations inherent to complex MMs.
Psychometric characteristics and feasibility of microinteraction-based Ecological Momentary Assessment in audiology research
Authors: Wu Yu-Hsiang , Stangl Elizabeth , Smith Samuel , Oleson Jacob , Miller Christi , Chipara Octav
Published: January 2025

Objectives

Microinteraction-based Ecological Momentary Assessment (micro-EMA) is a smartwatch-based tool that delivers single-question surveys, enabling respondents to quickly report their real-time experiences. The objectives of the two studies presented here were to evaluate micro-EMA's psychometric characteristics and feasibility across three response formats (2-point, 5-point, and 10-point scales) for adults with hearing loss.

Design

In the first study, thirty-two participants completed a dual-task experiment aimed at assessing the construct validity, responsiveness, intrusiveness, and test-retest reliability of micro-EMA across the three response formats. Participants listened to sentences at five signal-to-noise ratios (SNRs) ranging from −3 to 9 dB relative to the SNR for 50% speech understanding, answered the question “Hearing well?” on smartwatches, and repeated the sentences. In the second study, twenty-one participants wore smartwatches over 6 days. Every 15 min, participants were prompted to answer the question “Hearing well?” using one of the three response formats for 2 days. Participants provided feedback on their experience with micro-EMA.

Results

In the dual-task experiment, participants reported improved hearing performance in micro-EMA as SNRs and speech recognition scores increased across all three response formats, supporting the tool's construct validity. Statistical models indicated that the 5-point and 10-point scales yielded larger relative changes between SNRs, suggesting higher responsiveness, compared to the 2-point scale. Participants completed surveys significantly faster with the 2-point scale, indicating lower intrusiveness, compared to the 5-point and 10-point scales. Correlation analysis revealed that over two visits 1 week apart, the 2-point scale had the poorest test-retest reliability, while the 5-point scale had the highest. In the field trial, participants completed 79.6% of the prompted surveys, with each participant averaging 42.9 surveys per day. Although participants experienced interruptions due to frequent prompts, annoyance and distraction levels were low. Most participants preferred the 5-point scale.

Conclusions

The dual-task experiment suggested that micro-EMA using the 5-point scale demonstrated superior psychometric characteristics compared to the 2-point and 10-point scales at the tested SNRs. The field trial further supported its feasibility for evaluating hearing performance in adults with hearing loss. Additional research is needed to explore the potential applications of micro-EMA in audiology research.
Loading monocytes with magnetic nanoparticles enables their magnetic control without toxicity
Authors: Mödl Laura , Carnell Lucas R. , Stein Rene , Kerpes Andrea , Pfister Felix , Wirthl Barbara , Wall Wolfgang A. , Alexiou Christoph , Janko Christina
Published: January 2025

Background

With the help of superparamagnetic iron oxide nanoparticles (SPIONs), cells can be magnetically directed so that they can be accumulated at target sites. This principle can be used to make monocytes magnetically steerable in order to improve tumor accumulation, e.g., for immunotherapy with chimeric antigen receptor (CAR) monocytes. Here, we investigated the loading of monocytic THP-1 cells with SPIONs, analyzed their impact on the viability and cellular reactive oxygen species (ROS) generation and their magnetic enrichment. Finally, we compared and confirmed the experimentally generated magnetic enrichment data with computational simulations.

Methods and results

When THP-1 cells were incubated with citrate-coated SPIONs (SPIONCitrate) or citrate-stabilized gold-coated SPIONs (SPIONGold), cells ingested the particles, as determined via transmission electron microscopy and atomic emission spectroscopy. Flow cytometry showed that the particles were biocompatible and produced hardly any ROS. With SPION-loading, cells accumulated in Ibidi flow slides at the edge of a Neodym magnet, where the magnetic field and force were maximal, as calculated by our computational model.

Conclusion

THP-1 cells were successfully loaded with SPIONs, which exhibited excellent biocompatibility and provided the cells with magnetic steerability. The computational model predicted the actual magnetic accumulation of the SPION-loaded cells, enabling a more systematic and faster exploration of the design space in the future.
Enhanced production of ginsenoside compound K by synergistic conversion of fermentation with Aspergillus tubingensis and commercial cellulase
Authors: Lee Yong-In , Song Woo-Seok , Oh Deok-Kun
Published: January 2025

Fermentation of ginseng extract is limited by the low concentration of compound K (CK), a bioactive ginsenoside. In this study, a novel approach combining Aspergillus tubingensis fermentation with Aspergillus niger cellulase conversion was used to enhance CK production from high concentrations of American ginseng extract (AGE). The reaction conditions, including the feeding rate and concentrations of carbon source, enzyme type, AGE and enzyme concentrations, temperature, pH, and timing of enzyme addition, were optimized. Under optimized conditions, this combined method achieved an enhanced CK production of 8.06 g/L (13.0 mM) after 168 h, with a productivity of 48 mg/L/h. This approach led to a 2.0-fold increase in concentration and a 1.7-fold increase in productivity when compared with traditional fermentation using the same strain. The findings of this study demonstrate the synergistic effect of combining fermentation with enzyme conversion to improve CK production.
Particle image velocimetry analysis of the protective layer in embankment dams
Authors: Halaba Arachchige Senarathna Nisal Deelaka , Dezert Théo , Sigtryggsdóttir Fjóla Guðrún
Published: January 2025

The growing requirement imposed by dam safety regulations and guidelines necessitates the improvement and rehabilitation of rockfill embankment dams. These hydraulic structures are of great importance, and they can be subjected to overtopping flows which can significantly compromise the structural integrity. One of the defense mechanisms utilized is the placement of riprap on the downstream shoulder of the dam. This article explores eight experimental tests comprising of four different dam model configurations and investigates the possibility of Particle Image Velocimetry (PIV) techniques to explore the characteristics of the protective riprap layer, such as breach initiation, failure mechanism, and velocity pattern. The models varied from full to half dam profiles, constituted of placed or dumped riprap, with or without downstream toe support, and with or without downstream shell material. Leveraging the PIV technique, the study provides insight into the area of breach initiation within riprap protection on the downstream shoulder of rockfill embankment dams and thus breach initiation of protected rockfill dams. The study brings to light that for models with placed riprap, the initiation occurs simultaneously at the top and the bottom of the protective layer confirming the assertions made in prior studies regarding a failure mechanism marked by a sliding process. The study further confirms that for structures with toe support, the breach initiation occurs at the top of the protective layer. This analysis also revealed that in the case of dumped riprap, the precise position of the breach initiation was indeterminate. Furthermore, the analysis revealed that there is a significant drop in the velocity readings at the downstream section of the riprap layer when supported by a toe, underscoring the significance of having toe support. Another revelation from this analysis was the contrasting velocity readings with substantially higher readings for placed riprap as compared to dumped riprap reaffirming the fact that placed riprap can endure higher discharges as compared to dumped riprap. Furthermore, this investigation also detected that a graph of the velocity pattern depicting the placed riprap exhibited a higher singular peak while such a graph depicting the dumped riprap exhibited a bimodal characteristic.
Targeting heparan sulfate proteoglycans as an effective strategy for inhibiting cancer cell migration and invasiveness compared to heparin
Authors: Depau Lorenzo , Brunetti Jlenia , Falciani Chiara , Mandarini Elisabetta , Zanchi Marta , Paolocci Maria Francesca , Garfì Marta , Pini Alessandro , Bracci Luisa
Published: January 2025

By virtue of their ability to bind different growth factors, morphogens and extracellular matrix proteins, heparan sulfate proteoglycans (HSPGs) play a determinant role in cancer cell differentiation and migration. Despite a strong conceptual basis and promising preclinical results, clinical trials have failed to demonstrate any significant advantage of administering heparin to oncology patients. We exploited our anti-heparan sulfate branched peptide NT4 to test the opposite approach, namely, targeting HSPGs to interfere with their functions, instead of using heparin as a soluble competitor in human cell lines from pancreas adenocarcinoma, colon adenocarcinoma, rhabdomyosarcoma and two different breast cancers. We found that the anti-heparan sulfate peptide NT4 is more effective than heparin for inhibiting cancer cell adhesion, directional migration, colony formation and even cell growth, suggesting that targeting cell membrane HSPGs may be a more effective anti-metastatic strategy than using soluble heparin. Analysis of NT4 effects on cancer cell directional migration, associated to cellular distribution of HSPGs and cadherins in different migrating cancer cell lines, provided further indications on the molecular basis of HSPG functions, which may explain the efficiency of the HSPG targeting peptide.