bluuebunny/crossref_metadata_2025 huggingface dataset:
Gifts and Ritual
Authors: McCaskill Teresa Lee
Published: July 2024

Paul’s teaching about divine benefactions in Rom 12:6–8 extends the theme of worship that he establishes in Rom 12:1–2. Together, these passages address a uniquely gentile dilemma that many in his audience faced as new Christ-followers, which was the challenge of finding acceptable replacements for former cultic activities that were woven through all of life’s stages, from birth to death. One of the chief shortcomings of the scholars that have written about Rom 12:6–8 is a failure to address what Paul's gentile audience might have brought to his teaching and how his alignment of gifts with ritual (Rom 12:1–2) mirrored their polytheistic background. By analyzing examples from ancient texts and artifacts, Teresa Lee McCaskill shows that all seven of the terms Paul uses in Rom 12:6–8 would have had recognizable cultic antecedents for first-century worshipers in Rome. McCaskill presents a theoretical model that discusses how Paul’s gentile audience might have viewed the charismata and considered them as examples of sanctioned practices to replace former rituals. She also weighs the effectiveness of these particular gifts for furthering Paul’s missional objectives.
Innovations in Sickle Cell Care: Navigating the Dynamic Treatment Landscape
Authors: Ajoyemi Ala Oluwafemi
Published: July 2024

Sickle cell anemia (SCA) is a genetic blood disorder characterized by the presence of abnormal hemoglobin, leading to the formation of sickle-shaped red blood cells. This causes vaso-occlusive crises, chronic anemia, and organ damage. Recent advancements in SCA treatment, including genetic therapies like CRISPR-Cas9, stem cell transplantation, disease-modifying drugs such as hydroxyurea, and telemedicine, offer hope for improved patient outcomes. However, challenges such as access to care and high treatment costs persist. This review discusses recent advances in SCA treatment, highlighting the potential of these therapies to transform patient care and improve quality of life. SCA is a hereditary blood disorder caused by a mutation in the gene that encodes hemoglobin, a protein responsible for carrying oxygen in red blood cells. This leads to production of abnormal hemoglobin, hemoglobin S (HbS). When oxygen levels are low, HbS molecules can polymerize and cause red blood cells to become rigid and assume a sickle shape. These sickle-shaped cells can block blood flow, leading to vaso-occlusive crises, chronic anemia, and organ damage. Recent advancements in the treatment of sickle cell anemia have offered new hope for patients. However, on-going research activities offer hope for continued improvements in the management of this complex disease.
Therapeutic Potential of Medicinal Plants: Current Situation and Outlook
Authors: Emeje Martins , Ogu Eneojo , Chidebe Ifeoma , Roko Gautier , Abdullahi Munira , Sule Bibinu Daniel
Published: July 2024

Medicinal plants constitute the major therapeutic sources for the treatment and management of diseases among the large population of the African continent. The application of these plant resources for the management of ailments such as diabetes, cancer, neurodegenerative disorder, malaria, hypertension among others is based on the historical evidence of effectiveness, acceptability, affordability, accessibility and cultural compatibility. Various parts of medicinal plants such as flowers, leaves, stems, bark, roots, seeds, fruits possess therapeutic potentials due to the presence of bioactive substances in them. The therapeutic potentials of these medicinal plants are due to the complex interactions of the bioactive substances with their molecular target structures, such as the transport systems, enzymes and receptors. Currently, many well-known active substances derived from plants are included in medicines through scientific processing procedures that ensure standardization resulting in an improvement over the traditional crude practices among the various African cultures.
Exploring the Potential of Serendipita indica in Agriculture
Authors: Posada Adolfo , Patiño Rodrigo , Castro Dagoberto
Published: July 2024

This document discusses the characteristics and applications of the facultative endophytic fungus Serendipita indica, emphasizing its colonization of plant roots, enhancement of nutrient absorption, and promotion of plant growth under stressful conditions. S. indica can grow axenically on synthetic growth media and its symbiotic association with various plant species is highlighted. The production of chlamydospores, which aid in plant resistance and survival, is described. Additionally, the document outlines methods for cultivating S. indica, including its propagation in liquid media and inoculation of in vitro Mentha spicata plantlets. Experimental results demonstrate the significant impact of S. indica on plant survival and biomass. Furthermore, the fungus’s role in enhancing plant tolerance to pathogens and environmental stresses is discussed, highlighting its potential as a sustainable solution for improving plant development and agricultural productivity.
Sosialisasi Konsep Pertanian Berkelanjutan Di Kampung Napua Distrik Napua Kabupaten Jayawijaya
Authors: S Herlyani , Wulandari Futri
Published: July 2024

Traditional agriculture implemented in Napua Village, Napua, Jayawijaya  indirectly has a negative impact on the environment and the sustainability of food production. Socialization and assistance regarding the concept of sustainable agriculture is important to increase farmers' awareness in implementing more environmentally friendly and sustainable agricultural practices. This service activity aims to provide farmers with an understanding of the concept of sustainable agriculture. The implementation method is socialization in the form of delivering material about sustainable agriculture and assistance to farmer groups in practicing the concept of sustainable agriculture. The results of this socialization activity are the emergence of farmer awareness about the factors causing the decline in the quality and quantity of agricultural products in Napua Village and increased knowledge about the concept of sustainable agriculture as a solution to the problems.
Zoonyms as a means of naming humans in view of teaching Russian as a foreign language
Authors: Федосеев А.А. , Лидина И.Ю.
Published: July 2024

статья посвящена вопросам, связанным с обучением иностранных студентов использованию зоонимической лексики как средства наименования человека в современном русском языке. Знакомство с системой зоонимов, используемых для называния человека в русском языке, играет важную роль в понимании культуры страны изучаемого языка и способствует формированию культурологических компетенций, позволяет адекватно воспринимать ценности и антиценности русской культуры, формировать терпимость к инокультуре и ее носителям. Согласно коммуникативному и компетентностному подходам целью изучения иностранного языка является способность к межкультурной коммуникации, поэтому учебные материалы по иностранному языку должны быть ориентированы на знакомство с культурой этого языка, а зоонимы, встречающиеся в учебных текстах, являться прежде всего названиями животных, обитающих на территории страны изучаемого языка, типичных для неё Результатом обучения должно стать приобретение студентами следующих навыков: распознать в письменной и звучащей речи зоонимы; понимать выражаемое отношение говорящего/пишущего на основе контекста и интонации высказывания (положительное или отрицательное); понимать, какие свойства человека вызывают такое отношение (физические или духовные); оценивать допустимость услышанного/прочитанного употребления зоонима в конкретной ситуации и адекватным образом реагировать на него.

the article deals with teaching foreign students how to use zoonymical lexis as a means of naming humans in the modern Russian language. Knowledge of the system of zoonyms used for naming people is essential for understanding the culture of the target language country and facilitates forming cultural skills. It makes possible adequate perception of values and anti-values of Russian culture, as well as promotes tolerance of a foreign culture and culture bearers. In accordance with the communicative and competence-based approaches, the goal of studying a foreign language is cross-cultural communication. Hence, the educational materials should be target culture-oriented, and zoonyms which can be present in the reading texts should be the names of animals typical of the target country’s territory. The result of learning should be expressed as the following skills: to recognize zoonyms in written and oral speech; to understand the attitude (positive or negative) of the speaker/writer based on the context and intonation; to understand which properties (physical or mental) are the object of that attitude; to assess the acceptability of such usage and to adequately react.
Exploring Factors Influencing Parent's Purchase Intention Towards Mathematics Educational Comics
Authors: Antoni Tarisa Andika Putri
Published: July 2024

This research investigates the factors influencing parents' purchase intentions towards mathematics educational comics by expanding the Theory of Planned Behavior. Using a qualitative approach, the study conducted semi-structured interviews with ten parents of children in grades 1 to 3, selected through purposive sampling. The objective was to explore how various factors affect parents' decisions to purchase these educational materials. The study identifies several key characteristics that impact purchase intentions. Notably, teaching attributes such as the frequency and duration of use and parental attributes play a crucial role. The research also ranks the factors influencing purchase intentions in the following order: Perceived Behavioral Control, Attitude, Perceived Ease of Use, Perceived Value for Money, Subjective Norms, and Perceived Product Quality. This hierarchy reflects how parents prioritize these elements when deciding whether to invest in educational comics for their children. The findings suggest that Perceived Behavioral Control and Attitude are the most influential factors, highlighting the importance of how parents feel they can manage and benefit from the educational product. Perceived Ease of Use and Perceived Value for Money follow, emphasizing the need for user-friendly products that offer good value. Subjective Norms and Perceived Product Quality are also important but have a lesser impact than other factors. These insights are valuable for developing business strategies and marketing plans. By understanding and addressing these factors, companies can tailor their approaches to meet parents' needs better and enhance the appeal of mathematics educational comics.
Comparative Analysis Of Cost Calculation With Activity-Based Costing And Traditional Methods
Authors: Emmuel Prayer Waruwu  , Basram Pratama Sitanggang  , Petrus Irwando Simatupang  , Jeremy Togar Sitorus  , Hamonangan Siallagan
Published: July 2024

In the modern business world, accurate cost calculation is crucial for effective decision-making. Traditional methods often fail to reflect actual resource consumption, leading to inaccurate pricing and resource allocation. This research aims to analyze the use of Activity-Based Costing (ABC) and compare it with traditional methods. The research approach is qualitative, employing literature review methods. The findings show that ABC, which allocates costs based on activities performed, provides more realistic and accurate cost estimates. ABC helps companies identify non-value-added activities, improve efficiency, and reduce waste. Although ABC is more complex and expensive to implement, it provides more precise cost information, supporting optimal decision-making regarding pricing, product strategy, and resource allocation. Conversely, traditional methods are simpler but often result in less accurate cost allocation and do not reflect variations in activity consumption. Therefore, ABC is superior in terms of accuracy and effectiveness in identifying waste and inefficient activities, despite requiring technological support and higher initial costs.
Pelatihan Membaca 15 Menit Untuk Menguatkan Program Gerakan Literasi Sekolah (Gls) Peserta Didik di Pulau Pari Kepulauan Seribu Selatan
Authors: Irdalisa  , Sari Yessy Yanita , Fitriani Somariah
Published: July 2024

The literacy ability of Indonesian students is still in the low category, this is proven by the learning process so far not yet at the stage of acquiring knowledge, students adapting to students' desires in learning to acquire knowledge. Another thing is that the learning model still lacks the use of learning models in increasing students' literacy to become a habit in students' daily lives. The School Literacy Movement is an educational ecosystem that was formed with efforts to involve students, teachers, school principals, parents and local communities. So a collection of books is needed that integrates material with the surrounding environmental conditions to attract students' attention in reading, so that students' literacy can improve well. The community service methods used are in the form of training, mentoring carried out face-to-face through lectures and practice and distribution of interviews and observations. Participants in this activity were students of SDN Pulau Pari 01 Pagi. Service is carried out in several stages including planning, implementation, evaluation and mentoring. Data collection techniques are carried out through field observations, documentation, interviews and observations. The results obtained showed that students were able to understand reading after carrying out reading training using the reading aloud technique for 15 minutes.
Pemikiran Tokoh - Tokoh Pendidikan Islam Klasik (Sejarah Keilmuan Islam Interdisipliner)
Authors: Mahendra Arif Rianto Mahendra Arif Rianto , Afiful Ikhwan Afiful Ikhwan
Published: July 2024

Abstract: This Article will in-depth explore the views of classical Islamic education scholars and their relevance in shaping the people's framework of thinking. Understanding their thinking methods is an important foundation for achieving the desired social welfare. The main focus lies on the characteristics of Islamic religious education in the Abbasid era, including the concept of knowledge as rational (aqli) and inherited (naqli). The discussion involves educational curricula from elementary to high levels, highlighting the important role in developing holistic understanding. Overall, this journal reflects the intellectual heritage of classical Islamic scholars and their empowerment in directing the development of public thought.
The research method applied in this research is a qualitative approach.
This journal will summarize various sciences that developed during that period, including mathematics, astronomy, chemistry, physics, geography, medicine and philosophy. Furthermore, the thoughts of prominent figures such as Ibnu Sina, Ibnu Khaldun, Al-Ghazali, Al-Kindi, and Al-Khwarizmi received in-depth attention in the educational context. This journal not only records their contribution to the development of science, but also presents their views on Islamic religious education. By compiling these thoughts, this article becomes a comprehensive understanding of the intellectual foundations of that time. Through this in-depth analysis, readers can better understand the recognized scientific and educational legacy of classical Islamic thinkers, enriching their understanding of the intellectual developments of the period.
Peran Orang Tua Sebagai Pendidik Dalam Mampelajari Al-Qur’an Di Era Globalisasi
Authors: Zainul Alim Zainul Alim
Published: July 2024

Parents are the first people a child interacts with after he is born. Children will imitate everything their parents do, children's behavior is a reflection of their parents' behavior. If this behavior continues to be done repeatedly it will become a habit, because children are great plagiarists in imitating every behavior carried out by their parents, especially if the child is still in their golden age. Golden age or known as "the golden age", this age is a very important period for a child. Education in this age range really determines a child's next stage of development. These golden years are in the range from 0 to 8 years, children at this age experience very significant development in the process of their developmental stages. This age period is important because during this period there is a maturation of physical and psychological functions that are ready to respond to stimulation coming from the environment. Parents certainly really want their children to have good abilities in studying the Koran. So this is where the importance of the role of parents in educating children to love the Qur'an more by giving advice about the importance of studying the Qur'an, while at the same time giving examples of how to learn the Koran in a good and correct way, starting from reading with mahrojul letters to good and correct tajwid so that tart reading can be realized. Educating children to be able to learn the Qur'an can be done through habituation, setting a good example for children not just giving orders, giving advice in a good way at the right time is important, and continuing to supervise children so that they are always consistent in learning the Qur'an. Do not hesitate to give praise when the child has achievements in learning the Qur'an, for example the child has been able to read the Qur'an with tartil and gives reprimands to measurable and educational punishments if the child makes mistakes while reading the Qur'an. Parents certainly really want their children to have good abilities in studying the Koran. So this is where the role of parents is important in educating children to love the Qur'an more by giving advice on the importance of learning the Qur'an, as well as giving examples of how to learn the Qur'an properly and correctly starting from reading with mahrojul letters to good and correct tajwid so that tart reading can be realized. Educating children to be able to learn the Qur'an can be done through habituation, setting a good example for children not just giving orders, giving advice in a good way at the right time is important, and continuing to supervise children so that they are always consistent in learning the Qur'an. Do not hesitate to give praise when the child has achievements in learning the Qur'an, for example the child has been able to read the Qur'an with tartil and gives reprimands to measurable and educational punishments if the child makes mistakes while reading the Qur'an.
Pengaruh Strategi Reciprocal Teaching terhadap Hasil Belajar Tematik Terpadu Kelas V SDN Gugus 6 Pesisir Selatan
Authors: Kristiando Wahyu , Fitria Yanti
Published: July 2024

Research in the background by student learning outcomes that are not optimal. The purpose of the study was to determine the effect of the use of the Recipcoal Teaching Strategy on the learning outcomes of grade V students of SDN cluster 6 Pesisir Selatan. The type of research is quantitative research in the form of quasi-experimental design research using the non-equivalent control group design. The research was conducted at SDN 04 Pasar Taluk and SDN 22 Pasar Taluk. Sample data collection was carried out using the cluster random sampling technique. The instrument used is in the form of an objective test in the form of multiple choice. The data analysis technique used is t-test. Based on the results of the pretest obtained, the experimental class that applied the Reciprocal Teaching Strategy was 54.37 and the average posttest was 78.22 while the learning in the Control class using the conventional approach had an average pretest learning outcome of 53.89 and an average posttest of 68.41 Based on the hypothesis test carried out with the t-test obtained by calculating the ttable > which was 3.43 > 2,000 real level 0.05 It can be concluded that the Reciprocal Teaching Strategy has an effect on the results Students learn in integrated thematic learning in elementary school.
Analisis Kinerja dan Tingkat Pelayanan Ruas Jalan Raya Ciomas Kreteg Kabupaten Bogor
Authors: Hutama Vigie Priantika Putra
Published: July 2024

The development of transportation has an impact on increasing traffic flow. The increase in the number of vehicles and high levels of human movement will cause congestion if it is not balanced with adequate road infrastructure. The aim of the research is to identify the level of service and performance of road sections. Methodology is a method or technique used to test the validity of using certain research. The research location is on Jalan Raya Ciomas Kreteg, Bogor Regency because it is a residential and commercial area so it is busy every day. Data collection techniques are taken through surveys of geometric conditions, traffic flow, speed and side obstacles. The supporting data is obtained from the population according to the Central Statistics Agency. The survey was carried out during rush hour and it was discovered that the traffic volume was 1216.75 pcu / hour. The analysis results show that the capacity of Jalan Raya Ciomas Kreteg is 2201.45 pcu / hour and DS is 0.55, so the Jalan Raya Ciomas Kreteg section is in class C in the classification of road service levels.
Effect of hatha yoga and aerobic dance practice on selected vital capacity variable of adolescent boys”
Authors: Mitra Sanjoy
Published: July 2024

The aims of Hamha yoga in various Indian traditions have included physical special powers, bodily benefits such as slowing age effects, magical powers and spiritual liberation Yoga is an ancient Indian Philosophy. The purpose of the study was to evaluate acute physiological response, to find out the changes if any in Vital Capacity, following the Yoga and aerobic dance practices. The total subjects were 120 divided into four groups and their age ranges from 12– 16 years. The duration of total practice period were 6 weeks (3 days in a week for 30 minutes). Pre test and post test data were analyzed by paired ‘t’ test method. For obtaining the significant differences ANCOVA method was adopted. (Garrett, 1981). The organised yoga and aerobic dance program definitely improved their performance in selected physiological potentialities.
Analysis of Provincial Difference in Male Throwing Event if National Competition
Authors: Dutta Sourav , Mahato Arup
Published: July 2024

Purpose of the study was to analyze the provincial difference in performance in throwing event of male national competition. The 1st position holders for men category in throwing events of last ten National games (2010-2019) were considered as the subjects for the present study. The performance of target population was recorded from various secondary sources such as web pages, official site of IOC, Wikipedia, website of different athletics associations, sports journal etc. Then it was converted into standard points with the help of Word athletics recommend “IAAF scoring table” book. The subjects were divided in groups according to province. Then F-test (ANOVA) was applied. The best performance of shot put in men category in National Athletic competition was found in 2015. Haryana state performed the best performance in Shot put men categories. The best performance of Discus Throw in men category in National Athletic competition was found in 2016. Punjab state performed the best performance in long throw men categories. The best performance of Javelin throw in men category in National Athletic competition was found in 2018. Uttar Pradesh state performed the best performance in Javelin throw men categories.The best performance of Hammer throw in men category in National Athletic competition was found in 2016. Rajasthan state performed the best performance in Hammer Throw men categories.
The Effect of Astaxanthin as the Strongest Antioxidant on the Human Body.
Authors: Samoilova M. , Kosyreva T. , Voeikova O. , Dragunova S. , Sakanyan M. , Tuturov N. , Ezhova E. , Kozhokar A.
Published: July 2024

Periodontal is a set of complex complex tissues that hold the tooth. If the violation adequate oral hygiene in inflammation, in which the antioxidant defense system of the person is not coping According to the synthesis report of the who (1978), chronic gingivitis in the European population is found in almost 80 % of children 10-12 years old and up to 100 % of children aged 14 years. Traditional methods of treatment aimed at eliminating the microbial factor are not always effective enough. Thus, periodontal diseases are an urgent problem today. Of great interest is the natural Astaxanthin, which surpasses other antioxidants in its anti-inflammatory and immunomodulatory properties.
Hormonal Restructuring in the Body of Women During the Menstrual Cycle in the Context of the Influence on the Vocal Apparatus
Authors: Samsonov V.
Published: July 2024

Fluctuations in hormones during the menstrual cycle affect the vocal apparatus. During the follicular stage, a woman's voice improves every day until ovulation. After ovulation, with changes in hormonal balance, the vocal apparatus undergoes changes. Impaired vocalization of high notes, lack of breathing, and hoarseness accompany a woman several days before and during menstruation.
Pathogenetic Mechanisms of the Influence of SARS-COV-2 on the Pathology of the Thyroid Gland (Clinical And Experimental Study)
Authors: Ziablitskaia E.Yu. , Khabarov O.R. , Asanova E.R. , Zima D.V. , Bezrukov O.F.
Published: July 2024

In 2022-2024, the study of the pathogenesis of thyroid diseases is most relevant due to the increased level of stress and the emergence of various early and late consequences of the past COVID-19 pandemic.The purpose of the study is to study the pathogenetic mechanisms of the influence of SARS-COV-2 on the pathology of the thyroid gland in a model experiment on laboratory animals and in statistical studies of the structure of morbidity during the COVID-19 pandemic. In a model experiment on two species of laboratory rodents sensitive to the SARS-COV-2 virus, the morphology and molecular biology of thyroid tissue was studied using histological and immunohistochemical methods. In the clinical part of the work, a retrospective analysis of the structure of the incidence of surgical pathology of the thyroid gland was performed based on diagnostic results at the preoperative and postoperative stages over 4 years (2019-2023). All quantitative data are processed by statistical methods.Results were obtained indicating that, based on the pathophysiology of SARS-CoV-2 infection, patients with COVID-19 often experience symptoms of thyroid dysfunction, thyroiditis associated with antigenic mimicry of the virus and activation of a three-level regulatory axis, cytokine storm, autosensitization leading to damage to thyrocytes and initiating thyroiditis. These patterns were also revealed in a model experiment on humanized B6.Cg-Tg (K18-ACE2) 2 Prlmn Ifnar1- mice (Stock No. 035041, The Jackson Laboratory, USA) and Syrian hamsters sensitive to the virus. A retrospective analysis over a period of 4 years showed an increase in the number of patients with autoimmune thyroiditis and toxic goiter, an increase in the percentage of nodular formations requiring surgical intervention, with suspected atypia or with reliable signs of cancer (III-VI categories according to Bethesda) from 8.8% to 16 .6%, an increase in the incidence of papillary cancer by 10.3%. Thus, against the background of immunosuppressive therapy and the general negative impact on the body of severe acute respiratory syndrome caused by this type of coronavirus, it is important to pay close attention to the thyroid gland of patients, an appropriate assessment of low-grade fever and cardiovascular disorders is important, and further fundamental research is advisable to study the long-term consequences of the pandemic on carcinogenesis.
Comparison of the Effectiveness of Oral and Intravenous Antibiotics for the Treatment of Acute Sinusitis in Children at Skopje Hospital, Macedonia
Authors: Wilson Bernadette , Antonio Wallace
Published: July 2024

Introduction: Acute sinusitis is an infection of the sinus cavity that often occurs in children. Antibiotics are the primary therapy of choice for acute sinusitis, but the optimal route of administration remains a matter of debate. This study aims to compare the effectiveness of oral and intravenous antibiotics for the treatment of acute sinusitis in children at Skopje Hospital Macedonia.
Methods: A retrospective cohort study was conducted on children aged 2-12 years diagnosed with acute sinusitis at Skopje Hospital Macedonia between 2019 and 2022. Patient data were collected from electronic medical records, including age, gender, symptoms, clinical findings, outcomes supporting examinations, and antibiotic therapy. Patients were grouped by route of antibiotic administration (oral vs. intravenous) and analyzed for comparison of treatment effectiveness.
Results: A total of 200 children with acute sinusitis were included in this study. Of these, 100 children received oral antibiotics, and 100 children received intravenous antibiotics. The oral and intravenous groups did not show significant differences in demographic characteristics, symptoms, clinical findings, and results of investigations. The overall cure rate was 85% in the oral group and 90% in the intravenous group. This difference was not statistically significant (p=0.21). Subgroup analysis showed that oral antibiotics were as effective as intravenous antibiotics for children with uncomplicated acute sinusitis.
Conclusion: Oral and intravenous antibiotics are equally effective for the treatment of acute sinusitis in children at Skopje Hospital Macedonia. Oral antibiotics can be used as a first-line therapy option for acute sinusitis in children, taking into account the safety profile, cost, and patient compliance.
Cyclic behavior and critical part of eccentric braced frames with vertical links
Authors: Susanti Lilya , Narto Wijaya , Wiranatha Gde , Jallow Abdourahim
Published: July 2024

A vertical shear link-equipped reinforced concrete eccentric braced frame (RC-EBF) exhibits a unique behavior that has yet to receive much research. The vertical shear link is located separately from the main beam, so it does not interfere with its performance. Moreover, it gives structural retrofitting flexibility. To comprehend the structural strength of EBF compared to Concentric Braced Frames (CBF), the current work explored the cyclic deformation history of RC-EBF type Y (vertical shear links). It also sought to identify the critical frame components contributing to structural failure. The investigation involves nine specimens comprising CBF and EBF with 15 cm and 25 cm vertical linkages. Cyclic load-displacement histories revealed that the CBF configuration is the stiffest and most reliable one. The CBF structure exhibits equal deformation at higher cyclic loads than the EBF. Shear stress is the critical factor contributing to the structure's collapse, as demonstrated by the diagonal main crack in the current EBF samples.
Evaluation of cryoablation using a prototype cryoablation needle in swine liver
Authors: Son Hyunjoon , Lee Jonghyun , Han Sung Yong , Kim Tae In , Kim Dong Uk , Kim Daejin , Kim Gun-Ho
Published: July 2024

Background/Aims: Pancreatic cancer poses significant challenges due to its tendency for late-stage diagnosis and high mortality rates. Cryoablation, a technique used to treat various types of cancer, has shown potential in enhancing the prognosis of pancreatic cancer when combined with other therapies. However, its implementation is often limited by the need for lengthy procedures and specialized equipment. This study aims to develop a cryoablation needle optimized for endoscopic ultrasonography to simplify its application in treating pancreatic cancer.Methods: The study involved conducting cryoablation experiments on swine liver tissue. It utilized cryo-needles to evaluate the extent of cell death across various temperatures and durations of cryoablation.Results: The cryoablation system, which employed liquid carbon dioxide, achieved rapid cooling, reaching temperatures below –60 °C within 30 seconds and maintained the cryoablation process for 200 seconds. These conditions resulted in necrosis of the liver tissue. Notable cellular changes were observed up to 15 mm away from the cryoablation needle.Conclusions: This experimental study successfully demonstrated the efficacy of using a cryo-needle for cryoablation in swine liver tissue. Further trials involving pancreatic tissue are expected to verify its effectiveness, underscoring the importance of continued research to establish its role as a complementary therapy in pancreatic cancer treatment.
Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study
Authors: Yamashige Daiki , Hijioka Susumu , Nagashio Yoshikuni , Maruki Yuta , Fukuda Soma , Yagi Shin , Okamoto Kohei , Hara Hidenobu , Hagiwara Yuya , Agarie Daiki , Takasaki Tetsuro , Ohba Akihiro , Kondo Shunsuke , Morizane Chigusa , Ueno Hideki , Sone Miyuki , Saito Yutaka , Okusaka Takuji
Published: July 2024

Background/Aims: To date, only thinner-diameter metal stents have been evaluated for unresectable malignant distal biliary obstruction (UR-MDBO). This study investigated the outcomes and optimal cohorts for a 6-mm-diameter fully covered self-expandable metal stent (FCSEMS) compared with those for a 10-mm-diameter FCSEMS.Methods: This single-center retrospective cohort study included patients who underwent initial transpapillary metal stenting for UR-MDBO. Propensity score matching (1:1) analysis was performed.Results: Of 133/68 patients who underwent 6-mm/10-mm-diameter FCSEMS deployment, 59 in each group were selected. The median time to recurrent biliary obstruction was not significantly different between the groups (p=0.46). In contrast, use of the 6-mm-diameter FCSEMS resulted in a significantly reduced incidence of stent-related adverse events (AEs) (p=0.016), especially cholecystitis (p=0.032), and patients aged <70 years were particularly affected by this significant reduction. Among the patients in the end-stage cohort who were unable to continue chemotherapy after FCSEMS deployment, the free rate of stent-related events, including recurrent biliary obstruction and stent-related AEs, was significantly higher in the 6-mm group (p=0.027).Conclusions: For UR-MDBO, a 6-mm-diameter FCSEMS can be an optimal and safe option in the younger cohort with a relatively high risk of AEs and in the end-stage cohort requiring safer drainage without interference from stent-related events during times of poor prognosis.
The Role of the Use of IoT (Internet of Things) Microcontrollers in the Electronics vocational education sector in Practicum Learning
Authors: Wahyudi  , Yahya Muhammad
Published: July 2024

The Internet of Things (IoT) has emerged as a transformative force in various industries, and its application in the field of electronics education has the potential to revolutionize practical learning experiences. This research explores the important role of IoT microcontrollers in the vocational education sector, particularly in electronics, to enhance hands-on learning during practical sessions. This research investigates the integration of IoT microcontrollers into the curriculum of electronics vocational education programs, aiming to assess their impact on student engagement, skill development, and overall learning outcomes. Through a combination of qualitative and quantitative research methods, this study evaluates the effectiveness of incorporating IoT microcontrollers in practical exercises, comparing traditional methods with IoT-enhanced approaches. The findings of this study contribute valuable insights in the optimization of practical learning experiences in electronics vocational education.
Internacionais de Trabalhadores, Gramsci e a relação trabalho-educação: reflexões para a política educacional
Authors: Moraes Carmen Sylvia Vidigal , Alencar Felipe , Jacomini Márcia Aparecida
Published: July 2024

Defrontando-se com as contrarreformas neoliberais contemporâneas que aprofundam as desigualdades sociais e educacionais, este artigo tem como objetivo revisitar concepções e propostas de educação e sua relação com o trabalho, presentes historicamente nos movimentos de trabalhadores, e analisar em que medida podem contribuir, hoje, para as ações de resistência e organização de políticas educacionais das classes subalternas nas lutas por hegemonia. A discussão é realizada por meio de um estudo teórico-bibliográfico, que visa à divulgação de ideias do campo socialista para a educação. Indicamos que as propostas para uma educação emancipatória possuem longa trajetória histórica, e que os espaços de participação ativa dos movimentos do século XIX, em particular das Internacionais de Trabalhadores e na Comuna de Paris, foram meios de circulação de ideias pedagógicas para a educação integral da classe trabalhadora. São retomadas as formulações de Karl Marx, Paul Robin, Antonio Gramsci, Anatoli Lounatcharski e Nadezhda Krupskaya sobre o trabalho como princípio educativo. Destacamos as contribuições de Gramsci considerando a atualidade de seu pensamento para o debate educacional contemporâneo, no que diz respeito ao vínculo da escola com o processo de disputa de hegemonia e apreensão da realidade. Desse modo, situamos os desafios para a defesa intransigente da educação pública, laica, democrática e de qualidade socialmente referenciada numa formação humana, integral e científica, que dê aos filhos das classes subalternas a possibilidade de serem dirigentes e construírem o seu próprio futuro.
Creative Problem Solving and Communication in Entrepreneurship
Authors: XIA YAN
Published: July 2024

This abstract introduces a plug and play set of materials designed for teachers to use as flipped learning tasks in the context of proposal writing and persuasive presentations. These materials were developed based on interview videos featuring young local entrepreneurs, who provided valuable insights and perspectives into the importance of research, creative problem solving, communication and language skills.
PolyU students in discipline-specific subjects engage in project-based learning, where they write proposals and deliver persuasive presentations based on their unique understanding and ideas within their respective disciplines. Given the constraints of a tight 13-week schedule, flipped discovery and consolidation materials based on the interview videos have been developed, covering a range of topics related to research, proposal writing, and presentation skills.
This submission centers around two plug-and-play sets: Creative Problem Solving and Communication, which can be seamlessly integrated into existing teaching and learning materials as flipped warmer and consolidation activities. Students have expressed in focus group interviews how these materials have made their learning experience more authentic and transferable.
By incorporating relatable real-world examples and practical insights, these plug-and-play sets offer teachers a convenient and effective way to introduce engaging warm-up activities into their existing materials. Students are guided to reflect on their research process, creative problem-solving skills and communication skills which are essential for successfully communicating their discipline knowledge and ideas in proposal writing and persuasive presentations.
Survival and development of Cadra cautella (Walker) (Lepidoptera: Pyralidae) on cocoa bean and cocoa powder
Authors: Astuti Ludji Pantja , Sartika Putri Dewi , Mutala'liah Mutala'liah , Wulandari Ratna , Ramadhan Nino Trifatu
Published: July 2024

The almond moth Cadra cautella (Walker) is a notable stored product pest which can cause detrimental loss on stored cocoa. Cocoa can be stored in bean and powder forms. The information about survival and development of C. cautella on stored cocoa is limited. This research aimed to determine the effect of cocoa powder and cocoa bean in the storage against the survival and development of C. cautella. This research was conducted in Plant Pests Laboratory, Department of Plant Pests and Diseases, Faculty of Agriculture, Universitas Brawijaya. This research consisted of two treatments namely cocoa bean and cocoa powder with no choice method and repeated six times. The observed variables were number of larvae, pupae, male and female almond moth of F1 progeny, and developmental time of this insect. The t-test analysis was applied to determine the treatment effect. Results showed that the number of larvae, pupae, adult males and females of F1 progeny cultured on cocoa powder were significantly higher than on cocoa bean. The total developmental time and life cycle of almond moth were shorter on cocoa powder than on cocoa bean. Therefore, to store cocoa in powder form is riskier to the almond moth infestation rather than in bean form. Hence, it is suggested to take more concern on the cocoa powder storage better in order to minimize the almond moth infestation.
PENGETAHUAN DAN SIKAP MAHASISWI KEDOKTERAN UNIVERSITAS ISLAM AL-AZHAR MATARAM TERHADAP SADARI SEBAGAI DETEKSI DINI KANKER PAYUDARA
Authors: Tilka Ayattulla  , Made Agus Suanjaya  , Ahia Zakira Rosmala  , Dewi Utary
Published: July 2024

Kanker payudara menduduki peringkat kedua setelah kanker leher rahim yang menyerang kaum perempuan di dunia dan lebih dari 80% kasus kanker payudara ditemukan pada tahap lanjut, sehingga pengobatan menjadi lebih sulit dilakukan. Salah satu upaya yang dapat dilakukan untuk mendeteksi kanker payudara secara dini adalah melakukan SADARI (Pemeriksaan Payudara Sendiri). Penelitian ini bertujuan untuk mengetahui hubungan antara faktor usia, tingkat pengetahuan dan sikap dengan perilaku SADARI pada mahasiswi Fakultas Kedokteran Universitas Islam Al-Azhar. Penelitian ini merupakan penelitian kuantitatif dengan desain cross-sectional. Penelitian ini melibatkan 170 responden yang dipilih dengan teknik Simple Random Sampling. Hasil penelitian menggunakan uji Rank Spearman nilai p-value usia sebesar 0,020 (<0,05), tingkat pengetahuan sebesar 0,000 (<0,05), sikap sebesar 0,041 (<0,05). Kesimpulan dari penelitian ini terdapat hubungan yang signifikan atara usia, tingkat pengetahuan dan sikap dengan perilaku pemeriksaan payudara sendiri (SADARI) pada mahasiswi Fakultas Kedokteran Universitas Islam Al-Azhar.
HUBUNGAN USIA, JENIS KELAMIN, STADIUM HIPERTENSI, DAN DIABETES MELITUS DENGAN KEJADIAN PENYAKIT GINJAL KRONIS DI RSUD PROVINSI NUSA TENGGARA BARAT
Authors: Prabasuari Ayu Dwi , Kadek Dwi Pramana  , Hardinata  , Mamang Bagiansah
Published: July 2024

Penyakit ginjal kronis (PGK) merupakan masalah kesehatan masyarakat global dengan prevalensi yang terus meningkat  setiap  tahun. Menurut penelitian yang telah dilakukan sebelumnya, jenis kelamin mempengaruhi fungsi ginjal. Penelitian Prihatiningtias (2017)  menyatakan bahwa faktor risiko PGK paling banyak yaitu  hipertensi dan diabetes melitus. Selain itu juga  terdapat  penelitian  yang  dilakukan  oleh  Lilia (2019) didapatkan hasil bahwa tidak terdapat hubungan antara diabetes melitus dengan kejadian  PGK. Dalam  hal  ini  terdapat  perbedaan  hasil yang didapatkan dari beberapa penelitian sebelumnya, maka dari itu perlu dilakukan penelitian mengenai hubungan usia, jenis kelamin, stadium hipertensi, dan diabetes melitus dengan kejadian PGK.  Penelitian ini bertujuan untuk mengetahui hubungan usia, jenis kelamin,  stadium  hipertensi,  dan  diabetes melitus dengan  kejadian  PGK di RSUD Provinsi NTB. Metode penelitian yang digunakan yaitu case control dengan jumlah sampel sebanyak 242 dengan teknik pengambilan sampel yaitu consecutive sampling. Uji statistik yang digunakan yaitu uji chi square. Hasil penelitian menunjukkan bahwa distribusi frekuensi kelompok kasus dan kontrol ditemukan paling banyak pada perempuan dengan usia 40-59 tahun, dengan penderita PGK ditemukan paling banyak pada laki-laki dengan usia >60 tahun. Terdapat hubungan antara usia dengan kejadian PGK (p value = 0,000, OR = 26,000, CI = 6,692-101,015). Terdapat hubungan antara jenis kelamin dengan kejadian PGK (p value = 0,040, OR = 1,703, CI = 1,024-2,832). Terdapat hubungan antara hipertensi dengan kejadian PGK (p value = 0,000, OR = 2,142, CI = 2,068-3,221). Terdapat hubungan stadium  hipertensi  dengan  kejadian  PGK (p value = 0,000, OR = 13,300, CI = 3,478-202,227). Terdapat hubungan antara diabetes melitus dengan kejadian PGK (p value = 0,000, OR = 292,500, CI = 90,456-945,834). Terdapat hubungan yang signifikan antara usia, hipertensi, stadium hipertensi, dan diabetes melitus dengan kejadian PGK.
Breast Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
Authors: Gradishar William J. , Moran Meena S. , Abraham Jame , Abramson Vandana , Aft Rebecca , Agnese Doreen , Allison Kimberly H. , Anderson Bethany , Bailey Janet , Burstein Harold J. , Chen Nan , Chew Helen , Dang Chau , Elias Anthony D. , Giordano Sharon H. , Goetz Matthew P. , Jankowitz Rachel C. , Javid Sara H. , Krishnamurthy Jairam , Leitch A. Marilyn , Lyons Janice , McCloskey Susie , McShane Melissa , Mortimer Joanne , Patel Sameer A. , Rosenberger Laura H. , Rugo Hope S. , Santa-Maria Cesar , Schneider Bryan P. , Smith Mary Lou , Soliman Hatem , Stringer-Reasor Erica M. , Telli Melinda L. , Wei Mei , Wisinski Kari B. , Yeung Kay T. , Young Jessica S. , Schonfeld Ryan , Kumar Rashmi
Published: July 2024

Breast cancer is treated with a multidisciplinary approach involving surgical oncology, radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer include recommendations for clinical management of patients with carcinoma in situ, invasive breast cancer, Paget’s disease, Phyllodes tumor, inflammatory breast cancer, and management of breast cancer during pregnancy. The content featured in this issue focuses on the recommendations for overall management of systemic therapy (preoperative and adjuvant) options for nonmetastatic breast cancer. For the full version of the NCCN Guidelines for Breast Cancer, visit NCCN.org.
The Effect of Green Technology Innovation on Financial Performance in Manufacturing Companies Listed on the Indonesia Stock Exchange
Authors: Sri Nurdiyanti  , Susi Sarumpaet
Published: July 2024

This study was conducted with the aim of examining the effect of green process innovation variables and green product innovation on the company's financial performance with total asset turnover variables as control variables. The dance used in this selection is the Resource Based View (RBV) theory and stakeholder theory. The population used in the study were manufacturing companies listed on the Indonesia Stock Exchange (IDX) during 2020-2022. Sampling was carried out using purposive sampling technique. The number of samples used in this assessment was 400 samples. The results of this study indicate that green process innovation and green product innovation have a positive and significant effect on corporate financial performance. The results of this study also found that the control variable of total asset turnover is able to control the effect of green process innovation and green product innovation on corporate financial performance.