bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Visceral Fat Lipolysis Adaptation to High-Intensity Interval Training in Obesity-Prone and Obesity-Resistant Rats
Authors: Liu Yang , Li Yu , Cheng Baishuo , Feng Shige , Zhu Xiangui , Chen Wei , Zhang Haifeng
Published: December 2021

Background/objectives: Visceral obesity is one of the key features of metabolic syndrome. High-intensity interval training (HIIT) could effectively reduce visceral fat but its effects show strong heterogeneity in populations with different obesity degree. The mechanism may be related to the differential adaptation to training between obesity phenotypes, namely obesity prone (OP) and obesity resistant (OR). The aim of the present study was to compare adaptive changes of visceral adipose lipolysis adaptation to HIIT between OP and OR animals and further explore the upstream pathway.Methods: OP and OR Sprague Dawley rats were established after feeding a high-fat diet for 6 weeks; they were then divided into HIIT (H-OP and H-OR) and control (C-OP and C-OR) groups. After 12 weeks of HIIT or a sedentary lifestyle, animals were fasted for 12 h and then sacrificed for histology as well as gene and protein analysis. Visceral adipocytes were isolated without fasting for catecholamine stimulation and β3-adrenergic receptor (β3-AR) blockade in vitro to evaluate the role of upstream pathways.Results: After training, there were no differences in weight loss or food intake between OP and OR rats (P > 0.05). However, the visceral fat mass, adipocyte volume and liver lipid of OP rats decreased more than that of OR rats (P < 0.05). Meanwhile, the cell lipolytic capacity and the increase in the expression of β3-AR was higher in the OP compared with OR groups (P < 0.05). Although training did not increase sympathetic nervous system activity (P > 0.05), the cell sensitivity to catecholamine increased significantly in the OP compared with OR groups (P < 0.05). After blocking β3-AR, the increased sensitivity disappeared.Conclusion: With HIIT, OP rats lost more visceral fat than OR rats, which was related to stronger adaptive changes in lipolysis. Increased β3-AR expression, rather than altered sympathetic nerve activity, mediated this adaption.
Industrial Wastewater Treatment Technologies For Reuse, Recycle, And Recovery: Advantages, Disadvantages, And Gaps.
Authors: Mejía Ricardo , Maturana Aymer , Gómez Diego , Quintero Christian , Arismendy Luis , Cárdenas Carlos
Published: December 2021

To reduce demand and discharge, instead of industrial wastewater being poorly treated and disposed of, it can be recycled, reused, or recovered if it is properly managed, thus having a substantial decrease in the water requirement and environmental impacts. The challenge is to select the appropriate process or combination of processes to achieve this based on the wastewater quality. Consequently, the objective of this investigation is to review every technology from conventional through advanced, for reliable and sustainable wastewater treatment and derived sludges, focusing on advantages, disadvantages, and technical gaps for development. Even though there is a wide range of possible technologies, it was evinced that there is huge potential to exploit and make them economically and sustainably viable for waste processing and circular economy, even in the mature massively implemented wastewater treatment technologies in the industry. Overall, we identify that independently from the technology to be studied, the future investigations on every unit, especially on those not vastly implemented, should be focused on: (1) The capacity in removing selected pollutants and decreasing impurities, (2) energy efficiency, (3) environmental safety, (4) economic viability, (5) hybrid processes, and (6) sustainability by waste processing.
Dental Macrowear Reveals Ecological Diversity of Gorilla Spp.
Authors: Harty Tegan , Berthaume Michael A. , Evans Alistair R. , Galbany Jordi , Guy Franck , Hamada Yuzuru , Kullmer Ottmar , Lazzari Vincent , Romero Alejandro , Fiorenza Luca
Published: December 2021

Size and shape variation of molar crowns in primates plays an important role in understanding how species adapted to their environment. Gorillas are commonly considered to be folivorous primates because they possess sharp cusped molars which are adapted to process fibrous leafy foods. However, the proportion of fruit in their diet can vary significantly depending on their habitats. While tooth morphology can tell us what a tooth is capable of processing, tooth wear can help us to understand how teeth have been used during mastication. The objective of this study is to explore if differences in diet at the subspecies level can be detected by the analysis of molar macrowear. We analysed a large sample of second lower molars of Grauer’s, mountain and western lowland gorilla by combining the Occlusal Fingerprint Analysis method with other dental measurements. We found that Grauer’s and western lowland gorillas are characterised by a macrowear pattern indicating a larger intake of fruit in their diet, while mountain gorilla’s macrowear is associated with the consumption of more folivorous foods. We also found that the consumption of herbaceous foods is generally associated with an increase in dentine and enamel wear, confirming the results of previous studies.
Seroprevalence of major infectious causes of dairy cattle reproductive problems in central Ethiopia
Authors: Messele Yohannes Equar , Girmay Gebrerufael , Emeru Bezina Arega , Bora Shelema Kelbesa , Gudeta Workitu Firomsa , Dersso Betelhem Seyoum , Tegegne Desiye Tesfaye , Hurrisa Beksisa Urge , Yalew Shimels Tikuye , Werid Gebremeskel Mamu
Published: December 2021

Background
Reproductive problem is one of the main constraints of livestock genetic improvement efforts in tropical countries. The aim of this study was to determine the prevalence of major infectious causes of reproductive problems of dairy cattle in selected dairy farms in central Ethiopia. Overall 86 serum samples were collected from October 2018 to February 2019 from animals with history of reproductive problems. The collected serum was tested for antibody titer against Brucella species, Neospora caninum, Bovine Viral Diarrhea (BVD), Infectious Bovine Rhinotracheitis (IBR) and Q-fever using rose-bengal and enzyme-linked immunosorbent assay (ELISA) tests.
Result
Among the animals with the history of reproductive disordered; abortion, still birth and repeat breeding cases were found in 61.6%, 19.8% and 18.6%, respectively. The prevalence of IBR, BVD, Neospora caninum and Coxiella brunetti was found to be 79.1%, 38.4%, 3.5% and 1.2%, respectively. The combined infection of both BVD and IBR were detected in 21% of animals. Out of the total animals examined in this study, 95.9% of Jersey breeds were found seropositive to IBR than Boran-Friesian crosses (57.7%). The incidence of BVD was significantly higher in Boran-Friesian crossbred cattle than in Jersey which was found to be 69.3% and 14.3, respectively. The prevalence of IBR and BVD was directly proportional with age of the animal and parity.
Conclusion
Vaccination against IBR and BVD is not practiced in Ethiopia, the rising level of those diseases in dairy sector needs regular surveillance and control program.
Does Size Matter? Toxicity Effects of 5‐nm and 70‐nm Silver Nanoparticles on Hoplobatrachus Rugulosus Frog
Authors: Siri Sineenat , Bamroongnok Kamchan , Kuaprasert Buabarn , Janthima Ratima , Patakkhinang Sukhum , Krubphachaya Pongrit
Published: December 2021

With the increased usage of silver nanoparticles (AgNPs), the potential impacts of released AgNPs in the environment are increasingly concerned, especially to natural living organisms. Since the properties of AgNPs significantly depend on their sizes, this work aimed to compare the effects of 5-nm and 70‐nm AgNPs on toxicity and bioaccumulation in Hoplobatrachus rugulosus, the edible East Asian Bullfrog. The synthesized AgNPs were characterized by X‐ray diffraction and selected area electron diffraction analyses. Both 5‐nm and 70‐nm AgNPs caused mortality, reduced growth, induced abnormal development, generated cellular oxidative stress, and modulated cellular biomolecule pattern of frog embryos, but at different levels. The 5‐nm AgNPs caused harmful effects on the frog embryos more than 70-nm AgNPs, likely due to their small size to allow more accessibility into the cell. The mortality effects of AgNPs depended on the concentration, exposure time, and size. The malformation of frog embryos in response to AgNPs-exposure included scoliosis, lordosis, kyphosis, and yolk sac edema. Synchrotron Fourier transformed infrared analyses revealed that 5‐nm AgNPs significantly changed the profile of cellular biomolecules in the embryos, indicated by the spectral peaks assigned to lipid, carbohydrates, proteins, and nucleic acids. The bioaccumulation of silvers was dominant in eggs, followed by stomach, liver, kidney, and intestine, respectively, suggesting their translocation via blood circulation. The result of high accumulated silver in eggs and effects on embryonic mortality, growth, development, and cellular changes suggested the potential negative impacts of AgNPs on the sustainability of this frog in the environment.
Random World and Quantum Mechanics
Authors: Król Jerzy , Bielas Krzysztof , Asselmeyer-Maluga Torsten
Published: December 2021

Quantum mechanics (QM) predicts probabilities on the fundamentallevel which are, via Born probability law, connected to the formal randomnessof infinite sequences of QM outcomes. Recently it has been shown thatQM is algorithmic 1-random in the sense of Martin-L¨of. We extend this resultand demonstrate that QM is algorithmic ω-random and generic, precisely asdescribed by the ’miniaturisation’ of the Solovay forcing to arithmetic. Thisis extended further to the result that QM becomes Zermelo–Fraenkel Solovayrandom on infinite-dimensional Hilbert spaces. Moreover, it is more likely thatthere exists a standard transitive ZFC model M, where QM is expressed in reality,than in the universe V of sets. Then every generic quantum measurementadds to M the infinite sequence, i.e. random real r ∈ 2ω, and the model undergoesrandom forcing extensions M[r]. The entire process of forcing becomesthe structural ingredient of QM and parallels similar constructions applied tospacetime in the quantum limit, therefore showing the structural resemblanceof both in this limit. We discuss several questions regarding measurability andpossible practical applications of the extended Solovay randomness of QM.The method applied is the formalization based on models of ZFC; however,this is particularly well-suited technique to recognising randomness questionsof QM. When one works in a constant model of ZFC or in axiomatic ZFCitself, the issues considered here remain hidden to a great extent.
SDG 4 and SDG 8 in the knowledge economy: A meta-analysis in the context of post-COVID-19 recovery
Authors: Makarenko Inna , Plastun Alex , Petrushenko Yuriy , Vorontsova Anna , Alwasiak Stanislaw
Published: December 2021

Almost all human activity spheres, from the health care system to the education system, were unprepared for the pandemic. This, in turn, has slowed down the progress in achieving sustainable development goals. The Sustainable Development Goals 4 “Quality Education” and 8 “Decent Work and Economic Growth” were particularly vulnerable. In addition, the widespread concern was caused in the context of the transition to a “knowledge-based economy”. This paper analyzes the readiness of the scientific community to provide preconditions for the acceleration of these SDGs achievements. To do this, a meta-analysis of the academic literature on SDG 4, SDG 8, and the knowledge-based economy during 2015–2021 was conducted. Several special methods and instruments were used, including Scopus, WoS, VosViewer, Publish or Perish, Google Trends, and Google Books Ngram Viewer. The results show the inability of the modern academic community to provide a theoretical and empirical framework for a successful transition to a knowledge-based economy, taking into account the need to achieve sustainability. This is partly due to the relative subject novelty and the lack of academic attention. The challenges posed by the pandemic (lockdowns, unemployment, closing of educational institutions, financial flows reorientation, etc.) together with potential threats (new pandemic, climate change, population displacement, armed conflicts, etc.) necessitate a radical intensification of academic activity in economics to achieve SDGs.
Justicia ambiental y acciones constitucionales: estudio del acceso a la justicia en el Páramo de Pisba
Authors: Montañez Aldana Nancy Paola , Gonzalez Borda Juan Camilo , Corredor Naranjo Julián Antonio
Published: December 2021

El presente artículo busca analizar el acceso a la justicia ambiental en el caso del páramo de Pisba, en Boyacá, haciendo especial énfasis en el desarrollo y materialización de la llamada justicia procesal. Para cumplir con lo anterior, en primera medida se aborda la conceptualización y evolución de la justicia ambiental desde un marco histórico; en segundo lugar, se analiza el aspecto procesal de la justicia ambiental como elemento relevante para garantizar la participación efectiva de los actores sociales; en tercera medida, se realiza una descripción y caracterización del ecosistema de Páramo de Pisba para finalmente, estudiar las acciones judiciales constitucionales relevantes, a la luz de la noción de justicia procesal ambiental. Se concluye la relevancia de la justicia procesal y el acceso a mecanismos judiciales como herramientas que moldean la protección de los ecosistemas paramunos y, así mismo, garantizan la participación efectiva de los diferentes actores.
STOP-Bang as a predictor of obstructive sleep apnea-hypopnea syndrome in outpatients
Authors: Pedrozo-Pupo John Carlos , Egurrola-Pedraza Jorge Armando , Campo-Arias Adalberto
Published: December 2021

The STOP-Bang has been promoted as a valuable tool for identifying obstructive sleep apnea-hypopnea syndrome (OSAHS) in medical and surgical patients. However, its performance in Colombian samples is unknown. The objective of this study was to determine the clinimetric performance of the STOP-Bang index versus the study of polysomnography in patients from Santa Marta, Colombia. An accuracy study of diagnostic tests with a test-based approach was designed. Seven hundred sixty-two adults referred for polysomnography to evaluate OSAHS were included in the research. They were aged between 18 and 94 years old (mean=47.2, SD=13.4), 63.3% were men, and 46.5% were classified as obese. The STOP-Bang performance was compared against the best reference criterion, the hypopnea/apnea index determined by polysomnography. The diagnosis of OSAHS was confirmed in 461 (60.5%) and corroborated in 301 (39.5%). The area under the curve was 0.70 (95%CI 0.66-0.74), and the best cut-off point was 4, with a sensitivity of 79.2%, a specificity of 53.5%, the positive predictive value of 72.2%, the negative predictive value of 62.6%, positive likelihood ratio was 1.70, negative likelihood ratio was 0.39; OR=4.08 (CI95% 2.99-5.56) and Cohen's kappa of 0.33. As conclusions, performance indicators show that STOP-Bang...
Relación entre marcador genético de testosterona y elección afectiva en personas de la comunidad LGTBIQ+
Authors: Andrade-Salazar José Alonso , Gómez-Osorio Daniela , De La Pava-Álzate Valentina , Valencia-Hoyos Vanessa
Published: December 2021

Esta es una investigación empírico-analítica que tiene como objetivo encontrar la relación entre el marcador genético de testosterona (T), visible en un tamaño mayor del dedo anular respecto al índice, y la elección afectiva en personas de la comunidad LGTBIQ+. Se diseñó una plantilla para medir la diferencia entre ambos dedos, que contenía igualmente imágenes masculinas y femeninas de rostros lineales “fuertes” y redondeados “delicados”, así como una entrevista semiestructurada. El 54% de los participantes presentó T alta; el 34,5%, baja, y el 11,5% tenían dedos simétricos. El 13,5% eligió el rostro masculino con mayor T; el 14,5%, el de menor T, y el 9%, el rostro femenino con mayores niveles de T. En la elección de pareja, quienes tienen mayores niveles de T optan por la actitud dominante y un rostro fuerte (13%), y el 11%, por la actitud dominante y el rostro delicado. La influencia genética de la T en la homosexualidad no debe descartarse, al igual que la influencia de la crianza y el entorno. El indicador de T elevado se manifiesta en hombres y mujeres, pero es mayor en hombres. La T no influye concretamente en la elección del rostro de la pareja.
Prescripciones medicamentosas potencialmente inapropiadas en adultos mayores: una revisión sistemática
Authors: Bohórquez-Moreno Cristina , Castro-Vásquez Cristina , Ríos-Paternina Andrés , Manotas-Castellar Marco , Corbacho-Bolivar Brenda , Hernández-Bello Ladini
Published: December 2021

La polifarmacia en el adulto mayor es de interés para las autoridades sanitarias porque predispone a interacciones farmacológicas y efectos secundarios nocivos que pueden causar la muerte. El objetivo de esta revisión fue identificar las prescripciones medicamentosas potencialmente inapropiadas en adultos mayores, así como evaluar la calidad metodológica de los estudios disponibles. Se realizó una revisión sistemática en las bases de datos Pubmed, Dialnet, Scielo, Scient direct, Redalyc, Ovid. La ecuación de búsqueda fue: prescripción inadecuada AND medicamentos AND adulto mayor y sus equivalentes en inglés y portugués. Se encontraron, en la búsqueda inicial, 20.296 artículos y fueron incluidos finalmente en la revisión 42 artículos. Se encontró que el 50% de los artículos fueron de diseño transversal; el rango de prevalencia de MPI fue de 19,8% a 98,2%, detectados por los criterios de Beer, STOPP, START, PRISCUS, ACOVE, FROTA o MAI. Los MPI mayormente identificados fueron las benzodiazepinas y los factores que se asociaron fueron el número de medicamentos, la edad, el sexo y la presencia de comorbilidades.
Aspectos socio-culturales para la atención a mujeres embarazadas durante y después de la pandemia por Sars-Cov-2/COVID-19
Authors: Perafán-Ledezma Astrid Lorena , Mendoza-Curvelo Maira , Baquero-Porras Angélica , Martínez-Dueñas William Andrés , Vásquez-Munive Mirith Marina , Brito-Jiménez Ivone Tatiana
Published: December 2021

Para la Organización Mundial de la Salud (OMS) la atención perinatal en general y prenatal de manera específica constituyen un conjunto de acciones importantes para la salud y el bienestar bio-psico-social de las mujeres en embarazo. A raíz de la pandemia por Sars-Cov-2/COVID-19 se ha afectado negativamente el cuidado y la atención en salud que deben recibir las mujeres en gestación. Actualmente sabemos que la infección por Sars-Cov-2 incrementa el riesgo de preeclampsia, muerte fetal, nacimientos prematuros, ingresos a cuidados intensivos neonatales (UCIN) y otros efectos adversos maternos, fetales y neonatales. Además, también se ha reportado que esta pandemia y algunas estrategias de mitigación como el confinamiento, han afectado la salud mental (ansiedad y depresión) de las mujeres durante el periodo perinatal.
MOBILIDADE E DINÂMICA NO ESPAÇO RURAL E URBANO EM SÃO CRISTOVÃO NO ESTADO DE SERGIPE/BRASIL
Authors: VASCONCELOS Carlos Alberto , De SOUZA Ótávio César Juliano
Published: December 2021

O presente trabalho apresenta e discute as modificações ocorridas no espaço geográfico do município de São Cristóvão/SE, nas décadas de 1980, 1990 e 2000, no tocante à mobilidade e dinâmica do espaço rural e urbano. Utilizaram-se dados cadastrais de órgãos oficiais, como o IBGE, INCRA, DEAGRO e Prefeitura Municipal, pesquisa de campo, baseando-se em autores que tratam da temática, a exemplo de Corrêa (1995), Oliveira (1997) e Souza (2005), para a compreensão e elucidação dos acontecimentos. Observa-se um processo difuso de urbanização não centrado na sede, e sim seguindo da periferia em direção ao campus da Universidade Federal de Sergipe, próximo à área limítrofe com Aracaju. O rural e o urbano passaram por um processo de especulação pelo poder estatal.
#VEMPRARUA: TERRITÓRIO E TERRITORIALIDADES NAS MANIFESTAÇÕES BRASILEIRAS DE JUNHO DE 2013
Authors: SANTOS Gustavo Souza , CUNHA Maria das Graças Campolina
Published: December 2021

A redescoberta e a incursão de novos significados aos conceitos de território e de territorialidade passam pelos desafios próprios de cada tempo, que demandam definições acuradas para refletirem suas dinâmicas e transformações espaçotemporais na contemporaneidade. Objetivou-se aqui analisar a produção de territorialidades a partir das manifestações brasileiras de junho de 2013. Inicialmente reflete-se sobre a definição e dimensão do conceito de território, para a seguir, tratar da produção de territorialidades e atrelá-la às manifestações de 2013. A apropriação das ruas, os devires coletivizados, a integração identitária, as tramas de comunicação de difusão e transmissão de mensagens e o arranjo de um movimento de base ciberativista se concatenam na emergência de uma territorialidade expressiva. Territorialidade (i)material e palco de reconfigurações socioespaciais e políticas, na qual se presta o esforço desta reflexão.
pH-metric method for determining the solubility and solubility products of slightly soluble hydroxides and acids
Authors:   Institute of Chemistry, Chisinau, Moldova, Povar Igor , Spinu Oxana , Pintilie Boris
Published: December 2021

In this paper, original methods for determining such thermodynamic characteristics as solubility K S0 product (KS) or the activity product ( )of slightly soluble hydroxides and acids are communicated. Developed methods for determining KS and solubility S are based only on the pH values of the saturated aqueous solution for a known initial composition of the heterogeneous mixture and the equilibrium constants of an arbitrary set of possible side reactions in the aqueous natural systems. The determination of solubility S and solubility product KS is also possible in the presence of other hydroxides or acids of known concentrations. Deduced equations allow the calculation of such characteristics, as the equilibrium concentrations of the components of slightly soluble compounds in aqueous phase and the degree of precipitation γ of the solid phase for various initial concentrations of the components of the heterogeneous mixture which are known in the process of preparing the mixture, requiring only experimental pH values of a saturated solution. From the known experimental pH data, S and KS were calculated for a series of hydroxides and acids of arbitrary composition. The obtained results correlated well with the known tabular values. Analysis of a number of real systems illustrated the deduced expressions, including calculations and theoretical explanations.
Moving forward sustainable solutions for VOCs biotrickling filtration through co-immobilised microorganisms
Authors:   “Gheorghe Asachi” Technical University of Iasi, Soreanu Gabriela , Diaconu Mariana , Maier Stelian Sergiu , Volf Irina , Cretescu Igor
Published: December 2021

This study is moving forward with some available options for upgrading the biotrickling filters (BTFs) treating volatile organic compounds (VOCs) in air, in the light of lowering their greenhouse gas(GHG) emissions. One of such options refers to the addition of the microalgae component to the biological matrix involved in such systems, by (co)immobilization, for the capture of the carbon dioxide issued from the VOCs biodegradation and potentially contributing to the overall VOCs removal performance. Particularly, alginate beads with (co) immobilized microorganisms (microorganisms isolated from commercial compost and microalgae Arthrospira platensis PCC 8005) are for the first time tested for this purpose, as follows: beads with entrapped compost-based microorganisms and attached microalgae (BTF-I); beads with an entrapped mixture of microalgae and compost-based microorganisms (BTF-II). Although both options provided promising performances in treating air contaminated with ethanol (as a model VOC in this study), the last option exhibited lower CO2 emissions and higher packing bed durability, being more prone to further development and implementation.
pH-metric method determining the solubility and solubility products of slightly soluble salts of arbitrary composition
Authors:   Institute of Chemistry, Chisinau, Moldova, Povar Igor , Spinu Oxana , Pintilie Boris
Published: December 2021

The developed method of determining KS from pH metric data has a number of advantages compared to those used traditionally. First, in place of the residual concentrations of the salt components, only the pH value of the saturated solution is used in the derived expressions. Thus, the number of independent variables, which need to be measured experimentally, is reduced. Furthermore, the potentiometric method, used to determine the pH, is sufficiently accurate, simple and universal and does not necessitate the use of ion-selective electrodes. At the same time, the residual concentrations are usually measured by chemical methods, which are inferior in most cases, for several reasons, compared to the potentiometric method. Second, the KS value calculated by the developed method has a thermodynamic character. The organization of the experiment must be appropriate to the applied equations. Therefore, it is necessary to draw attention to the need for high accuracy in the process of preparing the initial solutions, because the initial concentrations of the precipitate components are included in the calculation formulas. The developed method for determining Ks can be applied for systems of any degree of complexity, which contain additional complexing agents.
Assessment of environmental pollution level caused by shipbuilding industry
Authors:   National Research and Development Institute for Industrial Ecology, Serban Gabriel Valentin , Niculescu Marcela , Iancu Vasile , Paun Iuliana , Pirvu Florinela , Manea Catalin , Chiriac Florentina Laura , Vasile Gabriela Geanina
Published: December 2021

The purpose of the paper was to create databases that would allow a proper assessment of the degree of marine pollution generated by the shipyard industrial sector. The study was conducted over a period of three years, between 2015 and 2017. The parameters determined for the waters collected from the shipyard were within the maximum allowed limits according to the norms in force. However, values very close to the maximum allowable limit were observed in the case of groundwater for nickel, determined from the drilling located near the fuel depot in 2015 and chlorides determined from the drilling located near the galvanizing workshop, both in 2016 and in 2017. The analyzed parameters for the soil samples, collected from various sampling points and different depths, were below the value of the alert thresholds for less sensitive soils, according to Order 756/97. The databases created for this study can contribute as an incipient basis for the development of larger studies that include other industrial sectors as well as a longer evaluation period.
Challenges Faced by Behavioral Genetic Studies: Researchers Perspective
from the MENA Region
Authors: Khabour Omar F. , Abu-Siniyeh Ahmed A. , Alzoubi Karem H. , Al-Sheyab Nihaya A.
Published: December 2021

Background:

Behavioral genetic studies are important for the understanding of the contribution
of genetic variations to human behavior. However, such studies might be associated with
some ethical concerns.

Methods:

In the current study, ethical challenges related to studies of genetic variations contributing
to human behavior were examined among researchers. To achieve the study purpose, the Middle
East and North Africa (MENA) region researchers were taken as an example, where the aftermentioned
ethical challenges were discussed among a group of researchers, who were the participants
of an online forum. Discussions and responses of the participants were monitored and were
later qualitatively analyzed.

Results:

Discussions revealed that several ethical challenges, including subjects’ recruitment, the
difficulty of obtaining informed consents, and issues of privacy and confidentiality of obtained data
as information leakage, in this case, will lead to social stigma and isolation of the participants and
their immediate family members. Jordanian social and cultural norms, faith, and the tribal nature of
the population were raised as a major challenge that might face conducting behavioral genetic
studies in the Arab populations of the MENA. The lack of regulation related to the conduction of
genetic studies, misunderstanding, and misuse of genetic information are other challenges. A full
explanation of genetic research and the current and future possible benefits/risks of such research
could be potential solutions.

Conclusion:

In conclusion, the MENA populations are tackled with major challenges in relation to
conducting research studies in genetics/antisocial behavior field/s. Establishment of guidelines related
to genetic studies, capacity building, increasing public awareness about the importance of genetic
testing, and enhancing responsible conduct of research will facilitate the conduct of such sensitive
studies in the future in the region.
Reduced Contextual Information During Future Thinking in Alzheimer’s Disease
Authors: El Haj Mohamad , Antoine Pascal
Published: December 2021

Objective:

This study assessed the ability of patients with Alzheimer’s Disease (AD) to
produce “when, where, and who” information during future thinking.

Methods:

AD patients and control participants were invited to imagine future scenarios. Future
thinking was analyzed with respect to the number of “when, where, and who” details. Analysis
showed fewer “when, where, and who” details in AD participants than in control participants. Fewer “when” than “where” details and fewer “where” than “who” details were observed in AD and
control participants.

Results:

Production of temporal information in participants with AD was found to be associated
with general cognitive functioning, as assessed with the Mini Mental State Exam. Future thinking
in AD is mainly associated with reduced contextual information.

Conclusion :

The diminished ability to construct time-related details during future thinking in AD
can be mainly associated with the diminished general cognitive ability in AD, and probably with
hippocampal compromise in the disease. We also propose a socio-emotional account according to
which, confronted with a limited-time perspective during future thinking, AD patients may tend to
maximize their emotional well-being by avoiding time-related information and thinking about
friends, family and beloved ones.
Qualitative Loop Analysis of Social-Ecological Connectivity: The Case of Bima Bay, West Nusa Tenggara
Authors:   Study Program for Coastal and Marine Resources Management, Graduated Program, IPB University, Dramaga Bogor, Indonesia, Munawar Munawar ,   Planning Bureau, Secretariat General, Ministry of Marine Affairs and Fisheries, Indonesia, Adrianto Luky ,   Department of Aquatic Resources Management, Faculty of Fisheries and Marine Sciences, IPB Campus, Dramaga Bogor, Indonesia,   Coastal and Ocean Resource Study Center, IPB Campus, Dramaga Bogor, Indonesia, Boer Mennofatria ,   Department of Aquatic Resources Management, Faculty of Fisheries and Marine Sciences, IPB Campus, Dramaga Bogor, Indonesia, Imran Zulhamsyah ,   Department of Aquatic Resources Management, Faculty of Fisheries and Marine Sciences, IPB Campus, Dramaga Bogor, Indonesia, Zulfikar Andi ,   Aquatic Resources Management Department, Raja Ali Haji Maritime University, Tanjung Pinang, Indonesia
Published: December 2021

The coastal area of Bima Bay will continuously experience increased development for the next few years along with its city development as “Waterfront City” and as a tourism village by the decision letter of the West Nusa Tenggara governor. The data used in this research are primary and secondary data with a purposive sampling method. The analysis results show that: 1) the basic network model does not significantly differ from the simulation model, 2) loop analysis based on seven scenario simulations combines six nodes with the assumption that if node Up, Ad, Hp, P, and Jv is unavailable, so the nodes gaining negative effect are Tt, Ti, Sp, II, Ic, and Dw. Sustainable management effort of the ecosystem in Bima Bay by observing the network connection between SES components to find out the component giving positive and negative effects in management policy-making. The simulation model using the goodness of fit test for model statistic obtains p-value 0.96 which means H0 received since p-value 0.96 > 0.05 points. There need sustainable efforts to maintain the Bima Bay ecosystem by observing the impact of network relation across the components in SES to find out the component with positive and negative impact in making management policies.
Welfare Level of Fishermen’s Household Around the Mangrove Ecosystem in Khairiah Mandah Village
Authors:   Mahasiswa Magister Program Studi Ekonomi Kelautan Tropika, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor-Indonesia, 16680, Mandela Hades , Fahrudin Achmad , Yulianto Gatot ,   Dosen Fakultas Perikanan dan Ilmu Kelautan, Institut Pertanian Bogor, Kampus IPB
Published: December 2021

The majority of fishermen are the small-scale group who are depending on marine resources which utilization results are unsettled so that this group vulnerable to a low welfare state. On the other hand, the abundant marine resources in the mangrove ecosystem have not been able to be managed optimally to improve the welfare of fishermen's household. Therefore, the purpose of this study is to measure the welfare state of fishermen's household around the mangrove ecosystem. This research was conducted in the Khairiah Mandah Village from December 2019 to January 2020 using a survey method. The technique was determining respondents using purposive sampling with 39 fishermen consisting of 13 fishermen who catch fish, 13 fishermen who catch shrimp, and 13 fishermen who catch crabs. Data analysis uses analysis of the level of family welfare with indicators of a prosperous family according to BKKBN. The results showed that the fishermen around the mangrove ecosystem were mostly in the Prosperous Family I group with a percentage of 56%. Besides, fishermen families who are in the Prosperous Family II group are 31%, Prosperous Family III is 8%, Pre-Prosperous Family is 5%, and none are included in the Prosperous Family III Plus group.
Diagnosis and Management of Vestibular Schwannoma: Focus on Dizziness
Authors: Nam Sung Il
Published: December 2021

Vestibular schwannoma (VS) is commonly encountered in the cerebellopontine angle and benign neoplasms that arise from Schwann cells of the eighth cranial nerve, which can show not only hearing loss but also various vestibular symptoms. Dizziness is the symptom causing significantly negative effect on quality of life in patients with VS. Here, we will review the dizziness in VS.
Bilateral Sudden Hearing Loss Caused by Basilar Artery Dissection: A Case Report
Authors: Lee Ho Byung , Roh Jieun , Lee Hyun Min , Choi Jae-Hwan
Published: December 2021

Bilateral sudden sensorineural hearing loss (SNHL) is rare, but a possible symptom of vertebrobasilar ischemia. A 69-year-old female patient with hypertension and atrial fibrillation presented with bilateral sudden hearing loss and vertigo without other neurological symptoms. On examination, she had left-beating horizontal nystagmus with positive head impulse on the left side. Pure tone audiometry revealed severe SNHL on both sides. Brain computed tomography angiography showed a dissection in the proximal portion of the basilar artery (BA) with occlusion of the mid-BA and bilateral anterior inferior cerebellar arteries (AICA), which confirmed on transfemoral cerebral angiography (TFCA). Left common carotid angiography demonstrated retrograde blood flow into the BA and right AICA via the left posterior communicating artery. During TFCA, her right hearing loss dramatically improved. Nine days later, follow-up TFCA showed an improvement of antegrade flow of the BA and AICA. We suggest that vertebrobasilar ischemia can be suspected in patients with bilateral sudden SNHL who present with risk factors for stroke.
Endolymphatic Hydrops in Vestibular Migraine Associated with Menière’s Disease: A Report of Two Cases
Authors: Lee Bit Na , Hwang Seung-Bae , Kang Jin-ju , Oh Sun-Young
Published: December 2021

Vestibular migraine and Menière’s disease have similar clinical features which are recurrent dizziness or auditory symptoms, so it is challengeable to establish the correct diagnosis. Herein, a 31-year-old male and a 56-year-old female showed recurrent dizziness with auditory symptoms and suffered from vestibular migraine. They met the diagnostic criteria for vestibular migraine, but the Menière’s diagnostic criteria were not satisfied as there was no hearing loss. Delayed intravenous gadolinium enhanced magnetic resonance imaging of the inner ear was taken to find out of correlation of the inner ear and revealed endolymphatic hydrops. This case can improve the understanding of the pathophysiology of a vestibular migraine associated Menière’s disease.
Virtual exchange for internationalisation at home in China: staff perspectives
Authors: Ganassin Sara , Satar Müge , Regan Ashleigh
Published: December 2021

Despite the central role of internationalisation strategies in the agendas of universities all over the world – with BRIC countries (Brazil, Russia, India, and China) emerging as powerful regional stakeholders – very few studies have investigated how internationalisation is interpreted and operationalised in non-Western contexts. We offer an exploration of Internationalisation at Home (IaH) (Robson, Almeida, & Schartner, 2018) in the context of Chinese Higher Education (HE) with a focus on the perceptions of staff. This qualitative study investigates how 15 teachers and administrators understand the practice of Virtual Exchange (VE) within their institution’s IaH agenda. Findings show that participants think that VE could contribute to internationalisation and provide an inclusive way of accessing international and intercultural experiences. VE has the potential to enhance internationalisation and global engagement of Chinese HE Institutions (HEIs). At the same time, its implementation presents challenges that require careful consideration and planning. These include means for establishing partnerships with a mutual understanding of realities, unique power dynamics among learner groups, and techno-political challenges.
Apps for Promoting Children’s Oral Health: Systematic Search in App Stores and Quality Evaluation
Authors: Ho Teresa C Y , McGrath Colman , Yiu Cynthia K Y , Lee Gillian H M
Published: December 2021

Background

Increasingly, mobile apps are being used to promote oral care. Many of them are aimed at children.

Objective

This study aimed to systematically search and evaluate apps that promote oral care and hygiene for children.

Methods

A broad search strategy (13 keywords) was developed to identify apps from Apple’s App Store and the Google Play Store in April 2019. After reviewing the apps’ titles and summaries, potentially relevant apps were downloaded for viewing. The quality of the apps that met the inclusion criteria was assessed by the Health on the Net Foundation Code of Conduct (HONcode) criteria for medical and health websites and the Scientific Basis of Oral Self-care (SBOSC).

Results

More than 3000 Apps were identified and 54 relevant apps informed the review. The quality of the apps according to the HONcode criteria was generally low. The mean HONcode score was 1.8/8.0. One-quarter of the apps had a HONcode score of 0 (14/54, 26%). The SBOSC score of the apps was evaluated based on a 6-point scale. The mean SBOSC score was 1.5/6.0; 19% (10/54) of the apps had a score of 0. There was a significant and positive correlation between HONcode and SBOSC scores (r=0.37; P<.01). More recently uploaded apps had significantly higher HONcode scores (P<.05).

Conclusions

There are many apps aiming to promote oral self-care among children. The quality and scientific basis of these apps are low. Newer apps are of higher quality in terms of scientific basis. There is a need to ensure high-quality and evidence-based apps are available. The effectiveness of apps in terms of oral care and clinical outcomes among children needs to be evaluated.
Operationalizing and Evaluating Synchronous Virtual Group Health Interventions: Wide-Scale Implementation at a Tertiary Care Academic Hospital
Authors: Hussain-Shamsy Neesha , McMillan Ian , Cook Sheridan , Furfaro-Argier Alyssa , Sadler Andrea , Delos-Reyes Faith , Wasserman Lori , Bhatia Sacha , Martin Danielle , Seto Emily , Vigod Simone N , Zaheer Juveria , Agarwal Payal , Mukerji Geetha
Published: December 2021

Group-based health interventions are an important component of health promotion and management. To provide continuity of care throughout the COVID-19 pandemic, our institution undertook a rapid pivot to delivering group-based health interventions via a videoconferencing service which was securely embedded into both the electronic medical record and the patient portal to sustainably address immediate health service delivery needs during the pandemic and beyond. In this paper, we (1) describe the institutionally driven operationalization of a system to provide integrated synchronous video group visits across our hospital and (2) present a proposed strategy to comprehensively evaluate outcomes regarding their implementation, quality, and impact. Lessons for other institutions and the potential future role of synchronous video group visits to enhance how care can be scaled for delivery are discussed.
Задоволеність лікарів-стоматологів професійною діяльністю
Authors: Krut A.G.
Published: December 2021

Актуальність. Підтримка задоволеності медичних працівників професійною діяльністю та мотивація їх до праці є одним із засобів ефективного управління людськими ресурсами. Від мотивації та задоволеності роботою медичного працівника залежить його здоров’я та пов’язана з ним якість життя пацієнта. Задоволеність як характеристика організаційної культури відрізняється серед лікарів різних спеціальностей. Мета дослідження: визначити рівень задоволеності професійною діяльністю лікарів-стоматологів закладів, що надають високоспеціалізовану стоматологічну допомогу. Матеріали та методи. Використані авторські структуровані анкети, що були заповнені 110 лікарями-стоматологами трьох регіональних закладів стоматологічної допомоги. Методи: соціологічний; медико-статистичний; логіко-структурного аналізу; узагальнення. Результати. У цілому лікарі-стоматологи надали високі оцінки задоволеності професійною діяльністю за 5-тибальною шкалою: 4,6±0,5 балів – лікарі КНП «Житомирське обласне стоматологічне медичне об’єднання»; 4,2±0,4 балів – лікарі КНП Харківської обласної ради «Обласна стоматологічна поліклініка», 4,3±0,9 балів – лікарі КНП «Чернігівська обласна стоматологічна поліклініка Чернігівської обласної Ради». Однак респонденти КНП «Чернігівська обласна стоматологічна поліклініка Чернігівської обласної Ради» висловили лише часткову задоволеність можливістю підвищувати кваліфікацію на робочому місці, станом забезпечення лікарськими препаратами, розхідними матеріалами та доказовими технологіями, рівнем заробітної плати (діапазон оцінок 3,5±0,9 – 3,7±1,1 балів). Виявлено, що найнижчі оцінки задоволеності лікарі-стоматологи усіх закладів надали професійним стосункам з колегами структурних підрозділів поліклініки, де вони працюють, адміністрацією, а також з лікарями інших закладів охорони здоров’я: оцінки коливалась, в залежності від закладу, в межах відповідно 4,2±0,4 – 4,4±0,7 балів, 4,4±0,5 – 4,5±0,5 балів, 4,0±1,0 – 4,4±0,7 балів. Висновки. При загальній високій задоволеності професійною діяльністю потребують удосконалення професійні відносини лікарів-стоматологів, покращення – стан ресурсного забезпечення закладів та можливості професійного розвитку лікарів; підвищення– заробітна плата. Отримана інформація може бути використана для прийняття управлінських рішень зі зміцнення організаційної культури закладу охорони здоров’я шляхом удосконалення менеджменту персоналу.
Analysis of Spatial Distribution of the Drought Hazard Index (DHI) by Integration AHP-GIS-Remote Sensing in Gorontalo Regency
Authors: Olii Muhammad Ramdhan , Aleks Olii  , Ririn Pakaya
Published: December 2021

Several regions across the world are presently experiencing a continuous increase in water scarcity due to the rise in water consumption resulting from population development, agricultural and industrial expansion, climate change, and pollution. Droughts are increasing in recurrence, severity, duration, and spatial extent as a result of climate change. Drought will be one of the most serious threats posed by climate change, often in conjunction with other effects such as rising temperatures and shifting ecosystems. Therefore, this study analyzes the spatial distribution of the Drought Hazard Index (DHI) by integrating AHP-GIS-Remote Sensing in Gorontalo Regency. AHP was used to determine the significance of each map as an input parameter for the DHI, while GIS-Remote Sensing was utilized to supply and analyze all input maps and the study outcome. The DHI assessment consists of four criteria, namely with Normalized Difference Vegetation Index accounting for the highest proportion at 42.9%, followed by Land Surface Temperature (33.6%), Normalized Difference Moisture Index (16.8%), and Topographic Wetness Index (6.7%), with the consistency of the underlying expert opinion measured by the consistency ratio of 0.048. The results indicated that the general hazard of drought in the Gorontalo Regency area was low (43.53%), with 17.87% of the whole area experiencing high hazard. The high class of drought was discovered to be centered in the central region of Gorontalo Regency, which was mostly used for agricultural and economic purposes, thereby enabling policymakers to have evidence to develop management policies suitable for local conditions. Therefore, despite the limits of climatology data, this study established the value of satellite-derived data needed to support policymakers in guiding operational actions to drought hazards reduction.
The Use of Drop-Structures to Increase the Dissolved Oxygen Level along the Cibarani Channel
Authors: Jonathan Wijaya  , Doddi Yudianto  , Fitriana Finna
Published: December 2021

The Cikapundung river basin community uses the Cibarani channel as a drainage system and water source for fishing. However, the test result released on 9th November 2020 revealed that the channel’s water quality failed to reach the class II raw water standards due to various domestic waste discharges. This led to the performance of various studies to identify pollution control techniques by limiting the wastewater discharge and quality, controlling the intake discharge, and using baffles. The Cibarani channel has a drop-structure that can improve the water quality, though the effect has not been previously detailed. Therefore, this study was intended to comprehensively examine the effect of the drop-structure along the Cibarani channel to improve water quality conditions, specifically the Dissolved Oxygen (DO) parameter. This study employed the one-dimensional HEC-RAS software to simulate the hydrodynamic and water quality conditions along the Cibarani channel, and the drop-structure was modelled using two alternatives consisting of a vertical wall and a steep riverbed. Subsequently, the drop-structure fitted with a vertical wall gave a more plausible reaeration rate of 125 day-1 and Root Mean Square Error (RMSE) value of 0.50. The placement of a similar configuration before the first housing of the channel increased the DO concentrations by an average of 4.37 mg/L. This was followed by the modelling of another drop-structure after the first housing to increase the DO levels at the downstream part. Eventually, the combination of the two new drop-structures succeeded in increasing the DO concentrations along the Cibarani channel to 3.3 - 6.9 mg/L.