bluuebunny/crossref_metadata_2025 huggingface dataset:
Looking for a storm in the beach-ridges: a microscale perspective from eastern Baltic
Authors: Kalinska Edyta , Weckwerth Piotr
Published: June 2022

Sand coastal landforms occur commonly around the world, and the western, southern and eastern Baltic Sea coast is one of them. The latter is rich in nearly parallel and rhythmic beach-ridges, which are related with the Holocene Baltic Sea history and serve as an archive of storminess and climate and sea level changes in the past. Sand sediment of beach-ridges in Gulf of Riga (Latvia) have not gained an attention in these terms, and thus were sampled and subjected to sediment particles (grains) analyses in a microscale. Scanning electron microscopy (SEM) has a great potential in determining the depositional environment and was applied to check out the grain shape, its surface, type of microtextures and their frequency. Parallel with this, an automated particle shape analyser was used to measure thousands of particles in dozen directions. Based on this, several grain parameters were produced, which provide an information about duration and type of sediment transportation. Combination of these two methods followed by the statistical methods led to robust insight in the sediment particle characteristic and past storm detection.

 

This study was supported by the Mobilitas Pluss Returning Research Project MOBTP34 “Time-transport-storminess – an experimental geological study of coastal system” funded by the Estonian Research Council in years 2017–2018, and the Research University – Initiative of Excellence: the Emerging Field “Global Environmental Changes” at Nicolaus Copernicus University in Toruń.
2D-frost weathering indices for rock walls 
Authors: Czekirda Justyna , Etzelmüller Bernd , Rempel Alan W. , Westermann Sebastian
Published: June 2022

The importance of frost weathering processes has long been discussed in the context of cold-climate landscape evolution. The 9 % volumetric expansion of in situ water when it freezes to ice was initially held responsible for generating the stresses that create and widen cracks in rocks. This theory has since been challenged by the theory of ice segregation in rocks, in which the growth of ice lenses is supplied by additional water that is drawn to the freezing front.  Numerical modelling and laboratory experiments suggest that segregated ice growth can generate enough stress to cause rock damage and is most intense between approximately -8 and -3 ℃ (the precise range depends on rock properties), in the so-called frost cracking window (FCW). The two theories of weathering have different implications for landscape evolution: (1) if in situ volumetric expansion is more important, most frost weathering should occur close to the freezing point, (2) if ice lensing is more important, most frost weathering should occur in the FCW. For the latter theory, several frost weathering indices have been developed based on such factors as the time spent vulnerable to cracking within the FCW, the magnitudes of ground temperature gradients that induce water transport, and other factors that affect water availability.

            In this study, we model ground temperature using the ground heat flux model CryoGrid 2D (Myhra et al., 2017) and apply the one-dimensional frost weathering index proposed by Rempel et al. (2016), where frost weathering potential is assumed to be correlated with porosity changes that accompany gradients in water flux. Here, we adjust the frost weathering index so that frost weathering potential is modeled in two dimensions. Our results predict spatial and temporal patterns of frost weathering in rock walls that can be tested in the field.

 

References

 

Myhra, K. S., Westermann, S., & Etzelmüller, B. (2017). Modelled distribution and temporal evolution of permafrost in steep rock walls along a latitudinal transect in Norway by CryoGrid 2D. Permafrost and Periglacial Processes, 28(1), 172-182. doi: 10.1002/ppp.1884.

Rempel, A. W., Marshall, J. A., & Roering, J. J. (2016). Modeling relative frost weathering rates at geomorphic scales. Earth and Planetary Science Letters, 453, 87-95. doi:10.1016/j.epsl.2016.08.019
Accuracy of direct georeferencing strategies to monitor geomorphological features
Authors: Gómez-Gutiérrez Álvaro , Sánchez-Fernández Manuel , de Sanjosé-Blasco José Juan , Lavado-Contador Francisco
Published: June 2022

Geomorphic systems face significant changes of climate, land uses, vegetation cover and socio-demographic characteristics. In this context, the accurate monitoring of geomorphological features may be a relevant tool to understand the consequences and the risks of these changes. At the same time, monitoring some geomorphic systems (for instance a coastal cliff) may be challenging, difficult and dangerous. The direct georeferencing techniques, which do not require acquiring Ground Control Points (GCP), recently integrated into new platforms (mainly Unmanned Aerial Systems or UAS) and sensors (photographic or laser) facilitate this task. Here we test the accuracy of direct georeferencing approaches for two UAS: a DJI Phantom 4RTK (P4) and a MD4-1000 LIDAR. Two flights were carried out to capture images with the P4 over a beach and a coastal cliff in Cantabria (N Spain): a) in Real Time Kinematic (RTK) mode receiving NTRIP corrections and b) without real time corrections to later process the data using a Post Processing Kinematic (PPK) approach with simultaneously registered data at permanent GNSS stations. The PPK approach for the P4 dataset was carried out using Redcatch software and three permanent stations located at different distances of the study area to analyse the influence of the baseline. The P4 datasets were processed by the Pix4Dmapper Pro photogrammetric software to produce 3D models. The same study area was surveyed by the MD4-1000 LIDAR UAS that performs in PPK mode and produces a 3D model. The MD4-1000 LIDAR dataset was processed using PosPac UAV and mdLIDAR processing software packages. Two datasets were used to test the accuracy of the resulting 3D models: a set of 18 check control points established in the study area and surveyed using a GNSS instrument in RTK mode and a 3D model surveyed by a Terrestrial Laser Scanner placed at 5 locations (23.4·106 points with a registration error of 7 mm).

The P4 RTK approach showed a Root Mean Square Error (RMSE) for the Z coordinate of 0.12 m against 0.02 m obtained for the PPK approach. The MD4-1000 LIDAR showed a RMSE for the XY coordinates of 0.03 m and 0.06 for the Z coordinate. These figures were corroborated by the 3D distances between each resulting model and the TLS 3D model. In terms of point density and coverage the P4 resulting point clouds outperformed that obtained by the MD4-1000 LIDAR system, except in vegetated surfaces, where the photogrammetric technique completely failed to reconstruct the surface (i.e. to calibrate the images). These results and figures may be useful for geomorphologists and surveyors interested on monitoring features without the need for GCPs.
Profil Organoleptik dan Uji Proksimat terhadap Bakso Sawi Pagoda (Tatsoi) dengan Fortifikasi Ikan Bandeng (Chanos Chanos)
Authors: Naibaho Netty Maria , Zamroni Ahmad , Salusu Heriad Daud , Rudito  , Hamka  , Numarini Eva
Published: June 2022

Sayuran dan ikan merupakan makanan yang sangat penting dalam proses metabolisme tubuh manusia karena mengandung nutrisi yang sangat baik. Meskipun sebagian besar penelitian terkonsentrasi dengan bahan dasar pembuatan bakso dari daging ikan, namun perlu diketahui bahwa tidak semua kalangan masyarakat dapat mengkonsumsi sayuran dan ikan, terutama anak-anak. Alternative penyajian sayur dan ikan yang dapat dikonsumsi anak-anak sampai orang dewasa adalah bakso. Sehingga penelitian ini bertujuan untuk mengetahui tingkat kesukaan panelis terhadap daya terima rasa, tekstur, aroma, warna dan untuk mengetahui kandungan gizi seperti kadar air, kadar abu, protein, vitamin, lemak berdasarkan metode by different. Desain percobaan bakso sawi pagoda dan ikan bandeng ini menggunakan Rancangan Acak Lengkap dengan perlakuan adalah rasio sawi pagoda dan ikan bandeng, yaitu w1 (95:5%), w2 (85:15%), w3 (75:25%), w4 (65:35%0, w5 (40:60%) dan w6 (30:70%). Hasil penelitian menunjukkan bahwa rasio sawi pagoda dan ikan bandeng memberikan pengaruh nyata terhadap kadar air, kadar protein, kadar vitamin C, kadar lemak dan sifat organoleptik hedonik untuk atribut warna dan aroma. Namun tekstur dan rasa menunjukkan berbeda sangat nyata terhadap bakso sawi pagoda fortifikasi ikan bandeng, dan berpengaruh tidak nyata terhadap kadar abu. Bakso sawi pagoda fortifikasi ikan bandeng dengan komposisi sawi pagoda 30% dan ikan bandeng 70% mendapatkan respons organoleptik hedonik terbaik.
Land-use patterns, location choice, and travel behavior: Evidence from São Paulo
Authors: De Abreu e Silva João , Lucchesi Shanna
Published: June 2022

Global South cities are vastly underrepresented in the literature that analyzes the relationships between location choice, land-use patterns and travel behavior. This paper aims to reduce that underrepresentation by bringing new evidence from a metropolitan region in the Global South. We estimate a Structural Equation Model to study the relationships between land-use patterns, location choice, car ownership and travel behavior, while controlling for self-selection, in the metropolitan region of São Paulo, Brazil. The model structure is adapted from previous applications to include variables related with specific aspects of the studied region, with the inclusion of informal work and people working two jobs, while simultaneously controlling for cohort effects associated with being a millennial. The results support the claim that land-use patterns influence travel behavior, even in a metropolitan area showing strong income-based spatial segregation levels. More specifically, commuting distance and car ownership act as important mediators in the relationships between the total amount of travel by mode and land-use patterns. In contrast to previous applications of this model framework, income plays a stronger role, an indication of relevant income-based residential sorting. Cohort effects are also visible, as millennials prefer to live in central, accessible, and mixed areas, own fewer cars, travel less by car, and use public transit and non-motorized modes more frequently.
Saúde Mental dos profissionais de enfermagem diante da sobrecarga de trabalho: uma revisão integrativa de literatura
Authors: Santos Amanda Ferreira dos , Martins Wesley
Published: June 2022

Analisar os fatores que desencadeiam transtornos mentais e comportamentais nos profissionais de enfermagem e sua influência sobre a qualidade de vida desses profissionais. Trata se de uma revisão integrativa da literatura por meio de um levantamento retrospectivo das pesquisas publicadas no período de 2017 a 2021.  A coleta de dados ocorreu em fevereiro de 2022 em artigos publicados nos últimos cinco anos. A busca foi realizada por meio de pesquisas nas bases Scientific Electronic Library Online (SCIELO), Biblioteca Virtual em Saúde (BVS-BIREME), e PUBMED. Foram selecionados dez artigos que obedeceram aos critérios de inclusão e foram divididos em duas categorias: estudos com foco na sobrecarga de trabalho e qualidade de vida; e estudos com foco na saúde mental. Foi constatado nos estudos que a saúde mental desses profissionais pode estar relacionada a fatores internos e externos ao trabalho. Desta forma, é preciso que as instituições implementem estratégias de intervenção para combater problemas e situações emocionalmente estressantes, propor estratégias de autocuidado, planos de capacitação para saúde e melhoria da qualidade de vida desses profissionais.
Sağlık İletişimi ve Hastanelerde İletişim Sorunları
Authors: KARABOĞA Feyza , KARDEŞ İrfan
Published: June 2022

Where there is life, there is a communication phenomenon. Communication has enabled the birth of inventions that make life easier and the development of technology. Communication, which has become more important, especially with globalization and population growth, should be emphasized in the field of health, where information transfer is vital. The quality of the relationship between healthcare professionals and patient-patient relatives affects many factors such as the motivation of healthcare professionals, patient satisfaction, diagnosis, and treatment process. At the same time, the prevention of violence in hospitals again depends on the effectiveness of communication between healthcare professionals and patient-patient relatives. In this study, health communication, levels of health communication and methods used in health communication; physician behaviors, sources of communication problems in hospitals, and recommendations to prevent violence in hospitals are discussed. Keywords: Health Communication, Public Relations, Communication, Communication Problems, Violence in Hospitals
Influence Factors of Road Maintenance for the Safety of Road Users on the Jakarta - Tangerang Toll Segment
Authors: Mudiono Cahyo , Widyaningsih Nunung
Published: June 2022

In an effort to fulfill the Minimum Service Standards (MSS) for toll roads according to the toll road law, all toll road business entities (TRBE) must fulfill them. This includes the Jakarta – Tangerang toll road section. Therefore, routine maintenance and maintenance of roads and facilities is always carried out. So that in toll lanes various maintenance activities are always found, in situations of very congested traffic conditions. And because maintenance activities use road lanes, this has an impact on the safety of toll road users. Data retrieval through questionnaires Phase I and Phase II with data sample collection tools using google form, observation, document collection, all data results will be analyzed using Microsoft excel and multiple linear regression using IBM SPSS version 21. From data analysis, potential factors are obtained. causing an influence on road safety during maintenance is the management of maintenance work, among which the influence is the management of work materials, management of the work environment, management of work equipment, management of work methods, and labor management. While the most dominant factor influencing individually is the management of the work environment.

Keywords: factor analysis, effect of maintenance, road user safety.
Ganglion of the Sternoclavicular Joint: First Case Report from Kashmir Valley
Authors: Khan Dr Subuh Parvez , Qadri Dr Shaika , Rouf Dr Abdul
Published: June 2022

Ganglion cyst is a common swelling observed near joints of hands and feet, usually occurring in adult population. Ganglia are rare in the pediatric population. Additionally, sternoclavicular joint ganglia are also exceedingly rare. Diagnosis is usually based on clinical examination, radiological investigations, or fine-needle aspiration cytology (FNAC). We hereby report a case of an 8-year-old girl who presented with a non tender, non erythematous swelling over the right sternoclavicular joint for 2 months. FNAC of the lesion was done and diagnosis of ganglion was made. The swelling disappeared completely on aspiration. The aspiration acted both as diagnostic and therapeutic modality. The patient is under follow-up for the chance of recurrence. The case illustrates the importance of keeping ganglion within the differential diagnosis for palpable subcutaneous masses, even in young children, especially when they are seen to connect to the joint. To the best of our knowledge this is the first time to report such a case from Kashmir valley.

Keywords: Ganglion cyst, sternoclavicular joint, pediatric age.
Peran Pemerintah Indonesia bersama IOM Dalam Mengatasi Masalah Perdagangan Perempuan Indonesia ke Timur Tengah Periode 2016-2019
Authors: Rahmawati Nur , Kusuma Ardli Johan
Published: June 2022

ABSTRAKPenelitian ini menganalisis tentang peran pemerintah Indonesia dalam menangani masalah perdagangaan  perempuan Indonesia ke Timur Tengah pada tahun 2016-2019. Namun di tengah upaya-upaya yang dilakukan, nyatanya pemerintah Indonesia juga memerlukan adanya sebuah elemen kerjasama dari sebuah lembaga ataupun organisasi, yang diharapkan mampu membantu upaya pemerintah untuk mengatasi masalah perdagangan perempuan yang terjadi di Indonesia, salah satu upaya pemerintah yaitu dengan menjalin kerjasama bersama Internastional Organization for Migration (IOM). Karena mengingat kasus tersebut merupakan kejahatan lintas negara yang terorganisasi yang tidak hanya terjadi didalam negara tetapi telah melintasi batas negara. IOM tidak hanya memenuhi kebutuhan bantuan yang berkaitan dengan fisik, namun juga menjamin dan memelihara lingkungan tempat tinggal yang terjamin kebersihan, keamanan hingga kenyamanan nya. Pemerintah Indonesia dan IOM sudah sama-sama melakukan upaya dalam menangani masalah perdagangan perempuan yang terjadi di Indonesia ke Timur Tengah tersebut, namun bukan berarti upaya tersebut menjamin akan berkurangnya masalah perdagangan orang yang terjadi di Indonesia.Kata Kunci: Indonesia, Perdagangan Orang, Internastional Organization for Migration (IOM), Timur Tengah.  ABSTRACTThis research analyzes the role of the Indonesian government in dealing with the problem of trafficking of Indonesian women to the Middle East in 2016-2019. However, in the midst of the efforts made, in fact, the Indonesian government also needs an element of cooperation from an institution or organization, which is expected to be able to assist the government's efforts to overcome the problem of trafficking in women that occurs in Indonesia, one of the government's efforts is to collaborate with international partners. Organization for Migration (IOM). Because considering that the case is an organized transnational crime that does not only occur within the state but has crossed national bordersIOM not only meets physical assistance needs, but also guarantees and maintains a living environment that is guaranteed cleanliness, safety and comfort. The Indonesian government and IOM have both made efforts to address the problem of trafficking in women that occurred in Indonesia to the Middle East, but this does not mean that these efforts will reduce the problem of trafficking in persons that occurs in Indonesia. Keywords: Indonesia, Human Trafficking, International Organization for Migration (IOM), Middle East
Resveratrol maintain Human Iliac Bone Marrow Mesenchymal Stem Cells Stemness through Sirtuin 1 Mediated Regulation of SRY-Box Transcription Factor 2: an in vitro and in silico study
Authors: Yahya Chairul , S. Rohman Mohammad , Hidayat Mohammad , P. Nugraha Alexander , A. Rantam Fedik
Published: June 2022

Sirtuin 1 (Sirt-1) - SRY-Box Transcription Factor 2 (sox2) axis maintains the stemness of human MSCs. Resveratrol may maintain stemness of human iliac bone marrow (BM)-MSCs. The aim of this study to investigate resveratrol effect on sox2 to maintain BM-MSCs stemness through an in silico and in vitro study. BM-MSCs was aspirated from orthopedic patients then, cultured in vitro. The study groups were into a control group, resveratrol group at doses of 0.1 μM and 1 μM. The characterization human iliac BM-MSCs was examined by immunocytochemistry analysis cluster of differentiation (CD)73, CD90, CD105 and CD45. The proliferation of human iliac BM-MSCs in each group was analyzed by MTT assay with various dose of resveratrol 0.01 μM; 0.05 μM; 0.1 μM; 0.5 μM; 1 μM respectively. A molecular docking was done to evaluate the interactions between resveratrol, sirt1 and Sox2 in silico. Resveratrol act as Sirt1 activator with high binding affinity between Sirt1 and Sox2 was -883.9 kcal/mol in silico. BM-MSCs at third, fourth, fifth and sixth sub-cultured with administrated resveratrol at dose 1 μM showed more confluent, less apoptosis and less senescence cells than control group. The characterization of human iliac BM-MSCs at third sub-culture showed that positive expression of CD73, CD90 and CD105 but lack of CD45 expression. There was no significant different of BM-MSCs viability percentage after administration of resveratrol with various doses (p>0.05). Resveratrol has an effect to regulate Sox2 expression that can maintain human illiac BM-MSCs proliferation, self-renewal and stemness in silico and in vitro.
Zoledronic Acid use and Adverse Drug Reaction (ADR)
Authors: Neldi Vina , Yulistiani Yulistiani
Published: June 2022

Bone is the part of body that most common for metastasis solid tumors. Bisphosphonates are an effective treatment for preventing bone damage events and improve quality of life patients. Zoledronic acid (ZOL) is the third generation of nitrogen-containing bisphosphonates (NBPs) that can inhibit osteoclasts in the process of bone resorption. Mechanism action of this drug related to affinity with hydroxyapatite crystals of bone, through a high bone turnover result in reducing speed of bone remodeling. This drug has higher affinity compared with other bisphosphonates for bonding hydroxyapatite . Zoledronic acid internalizes into osteoclasts, which disrupts the metabolic process and function of osteoclast cells and accelerates the occurrence of apoptosis. In the other hand it has adverse drug reactions mild to moderate which have reported but the mechanism still unclear such as hypocalcaemia and secondary hypophosphatemia, acute phase response (APR), renal toxicity, and osteonecrosis of the jaw (ONJ). Adverse drug reaction can cause harm to patient indeed arise death, highly recommended to offer monitoring for patients.
A Review of Genus Garcinia Sp as Potential Sources of Therapies Against Obesity and Dyslipidemia
Authors: Khutami Chindiana , Sumiwi Sri Adi , Muchtaridi Muchtaridi
Published: June 2022

Obesity is a disease caused by an imbalance of food intake with the energy expended. While dyslipidemia is a complication of lipid disease in the body that can trigger various complications such as cardiovascular disease. Research on antiobesity and antidislipidemia has been done to obtain compounds that can overcome obesity and dyslipidemia because synthetic drugs that have been traded in the community still cause many adverse side effects, one of which is research from the genus Garcinia species. The method for finding reference sources in this review used “Pubmed” database with the keywords "Antiobesity of garcinia", “Antihyperlipidemic OR obesity AND garcinia” and “Obesity OR dyslipidemic AND garcinia”. From the inclusion results, 19 journal articles were discussed in this review. Based on the review results from these reference sources, 9 species of the genus garcinia have activity as antiobesity and antidyslipidemia, namely G. mangostana, G. atroviridis, G. pedunculata, G. dulcis, G. gummi gutta, G. cambogia, G. brasiliensis, G. indica and G. kola.
Dental Bioinformatics – Current Scope and Future perspectives
Authors: Manickam Natarajan Prabhu
Published: June 2022

Endeavors in bioinformatics and their link to oral biology has revolutionized the way we understand oral diseases. The power of computing and analysis applied to clinical data has remarkably improved the diagnostic and therapeutic potential of clinicians by large. In this direction, this paper addresses key regions of bioinformatics and their scope in dentistry. Microarrays are used in diagnostic, therapeutic and prognostic purposes. The scope of neural network analysis is presented. The power of computer aided image analysis for images from various medical imaging techniques are discussed. Various modalities by which genomics, proteomics and metabolomics revolutionize dentistry and lacuna in their practical realization projected. Finally, the goal of clinical medicine, the personalized clinical care is highlighted on its link to bioinformatics.
A Review on Phytochemical Investigations and Biological Activities of Trachyspermum ammi (L.) Sprague
Authors: Javed Naquvi Kamran , Ansari S. H. , Salma Afrin , Ahamad Javed , Najib Shehla
Published: June 2022

Trachyspermum ammi L. Sprague syn. Carum copticum Benth. & Hook, commonly known as ajwain, is an annual aromatic and herbaceous plant of the family Apiaceae. The fruits of T. ammi are native to Egypt and widely cultivated in Iraq, Iran, Afghanistan, Pakistan, and distributed throughout India. Ajwain is commercially cultivated in Rajasthan, Madhya Pradesh, Andhra Pradesh, Gujarat (Surendranagar, Saurashtra region), Maharashtra, Uttar Pradesh and other states also. Traditionally the plant is used in Ayurvedic and Unani formulations for the treatment of various disorders like flatulence, dyspepsia, diarrhoea, abdominal pains, piles, and bronchial problems, lack of appetite, galactogogue, asthma and amenorrhoea. It has been reported to possess many pharmacological bioactivities like antimicrobial, antioxidant, hypolipidaemic, antihypertensive, antispasmodic, antiasthmatic, antitussive, and many more. This review summarizes the reported traditional benefits, phytochemical and pharmacological studies of T. ammi.
Development and Application of Diagnostic Reference Levels for Adult Patients in Diagnostic Radiology
Authors: Druzhinina Yu. V. , Lantukh Z. A. , Vodovatov A. V. , Morozov S. P. , Ryzhov S. A. , Sokolov E. N. , Shatenok M. P. , Chipiga L. A. , Tolkachev K. V.
Published: June 2022

Radiation protection of patients is based on the principles of justification and optimization. The principle of optimization, the most important and effective one, relies on the system of diagnostic reference levels (DRLs) that have been successfully used in global practice and are officially introduced in Basic Sanitary Rules for Radiation Safety-99/2010.

The guidelines establish diagnostic reference levels for adult X ray imaging in medical settings and determine their application to balance radiation protection of patients and the provision of high-quality diagnostic information. The guidelines relate to medical X-ray diagnostic and radiological examinations and are intended for the staff and management of medical facilities, agencies that are responsible for radiation control in medical facilities, and can also be used by expert institutions and agencies for health security and disease control.

The guidelines consider and compare various methods to determine the DRLs based on measured and/or calculated dosimetric parameters, such as the dose-area product, entrance dose, mean glandular dose, activity, and effective dose. Furthermore, they propose a scheme to determine the standard dose values depending on the type of X-ray diagnostic device used; present the steps to apply the DRLs in practice; establish measures in case the standard doses exceed the DRLs; and define the levels to perform optimization.
İskemi Reperfüzyon Hasarında Stres ve Hücre Ölümü
Authors: BOZOK Ümmü Gülşen , KÜÇÜK Ayşegül , ARSLAN Mustafa
Published: June 2022

İskemi-reperfüzyon hasarı, miyokard enfarktüsü, iskemik inme, akut böbrek hasarı, periferik arter hastalığı, orak hücre anemisi dahil olmak üzere çok çeşitli patolojilerin morbidite ve mortalitesinde rol oynar. İskemide kan akımındaki azalmanın derecesine ve süresine bağlı olarak hücreler metabolik ihtiyaçlarını karşılayamaz. Hızlı reperfüzyon, oksijen açlığı çeken hücrelerin kurtarılması için gerekli olmasına rağmen, hücrede oluşan oksijen paradoksu hücreleri strese sürükler. Reperfüzyon ile birlikte ortaya çıkan stres yanıtı sınırlandırılamazsa hücre ölüm programları aktive olarak hücre ölür. Bu derlemenin amacı iskemi reperfüzyon hasarında rol oynayan hücresel stres mekanizmalarını ve ölüm programlarını tanımlamaktır.
Bir Aile Sağlığı Merkezine Başvuran Diabetes Mellitus ve/veya Hipertansiyon Hastalarının Anksiyete ve Depresyon Açısından Değerlendirilmesi: Kesitsel Bir Çalışma
Authors: KAYIR Tuba , ÖZTEKİN Coşkun
Published: June 2022

Amaç: Diyabet,hipertansiyon gibi kronik hastalıklar zaman içinde çeşitli organ fonksiyonlarında bozulmaya neden olur. Bu durum psikiyatrik hastalıkları beraberinde getirir. Bu çalışmada amacımız; bir aile sağlığı merkezine başvuran diyabet ve/veya hipertansiyon hastalarının depresyon ve anksiyete riskini ve düzeyini belirleyerek, bazı bağımsız değişkenlerle olan ilişkisini araştırmaktır.

Gereç ve Yöntemler: Bu çalışma 01 Ekim 2018-01 Şubat 2019 tarihleri arasında gerçekleştirilmiştir. Aile Sağlığı Merkezi'ne başvuran toplam 330 diabetes mellitus ve/veya hipertansiyon hastasına sosyodemografik veri anketi ile birlikte Beck Depresyon Envanteri ve Beck Anksiyete Envanteri yüz yüze görüşme tekniğiyle uygulandı. Hastalar sadece hipertansiyonu olanlar,sadece diyabeti olanlar ve hem hipertansiyon hem de diyabeti birlikte bulunanlar olarak üç gruba ayrıldı.

Bulgular: Çalışmaya alınan hastaların 226’sının kadın,104’ün erkek olduğu saptandı. Yaş ortalaması 53,69±7,24 yıl olarak tespit edildi. Hastaların 66’sı diyabet,181’i hipertansiyon ve 83’ü diyabet+hipertansiyon hastası olduğu görüldü. Diyabet grubunda %42,4, hipertansiyon grubunda %32,5, hem diyabet hem de hipertansiyon grubunda ise %40,9 oranında anksiyete bozukluğu saptanırken, depresyon oranlarına bakıldığında diyabet grubunda %31,8, hipertansiyon grubunda %28,7, hem diyabet hem de hipertansiyon grubunda ise %32,5 oranında gözlendi. Grupların yaş dağılımında,eğitim düzeylerinde,egzersiz sıklığında istatistiksel olarak anlamlı farklılık bulundu (p
Dabigatran Kullanımına Sekonder Nadir Görülen Ciddi Koagülopati
Authors: UÇAK BASAT Sema , SİVRİTEPE Ridvan , ORTABOZ Damla , SEVİM Ecem
Published: June 2022

Dabigatran atriyal fibrilasyon (AF) varlığında oluşabilecek inmelerin önlenmesinde kullanılan oral direkt trombin inhibitörüdür. Vitamin K antagonistleri ve varfarin kullanımına kıyasla kanama yan etkilerinin daha az görülmesi ve laboratuar takibi gerektirmemesi açısından güvenle tercih edilebileceği savunulmaktadır. Bu yazıda dabigatran kullanımına bağlı ciddi kanama bozukluğu gelişen 83 yaşındaki bilinen kronik renal hasar, epilepsi, AF tanıları olan bayan hasta sunuldu. Oral antikoagülan ilaçlar atriyal fibrilasyon olgularında sistemik tromboemboliler ve iskemik inmelerin önlenmesinde önem arz etmektedir fakat vakamızda olduğu gibi ciddi kanamalara yol açabilmektedir. Renal yetmezlik gibi hastalığı olan yaşlı hastalarda antikoagulan ilaçların doz ayarlanması dikkatlice yapılması gerekmektedir. Vakamız dabigatran kullanımına bağlı kanama ile PT, aPTT ve INR değerlerinde belirgin uzamanın görüldüğü nadir vakalar arasında yer alması nedeniyle ilginçtir.
Connecting to Figure Out How to Teach ESOL: A Grounded Theory
Authors: Bytheway Julie
Published: June 2022

What can we learn from people who taught themselves how to teach ESOL?
This PhD research explored how teachers who started teaching English to Speakers of Other Languages (ESOL) in post-secondary education without teaching or applied linguistics qualifications or prior teaching experience figured out how to teach. Grounded theory was used to explore the social context and guide cyclic, flexible research processes. Seven participants shared their perspectives during semi-structured interviews. Constant comparative analysis was used to identify properties, concepts, categories, a basic social process, and a grounded theory. The substantive grounded theory of Connecting to Figure Out How to Teach ESOL explains how teachers who started teaching ESOL in post-secondary education without teaching or applied linguistics qualifications or prior teaching experience discovered and determined how to teach ESOL. Connecting to Figure Out How to Teach ESOL is an informal and holistic learning process that includes four interdependent and interconnecting parts: becoming (a) Willing by initially acknowledging not-knowing how to teach and taking responsibility for students’ learning; (b) Reflecting by recalling learning experiences, and evaluating language, learning and teaching; (c) Engaging by building relationships with students, collaborating with teachers, and using learning resources; and (d) Adapting by engaging in interconnected cycles of monitoring students’ responses, determining students’ wants and needs, and experimenting with teaching.
Warning messages to prevent illegal sharing of sexual images: results of a randomised controlled experiment
Authors: Prichard Jeremy , Scanlan Joel
Published: June 2022

Illegal distribution of sexual images by adults and minors is an expanding problem. We examined whether messages would dissuade men (18–32 years) from visiting a fake website offering access to free pornography to users who uploaded a sexual image of a woman. Participants seeking to enter the site (n=528) were randomly assigned to one of three conditions. Group 1 went straight to the landing page. Group 2 encountered a text warning that sharing sexual images of people who appear under 18 years old is illegal; Group 3 received the same message with an accompanying animation. Sixty percent of Group 1 participants attempted to access the site, compared with 43 percent in Group 2 and 38 percent in Group 3. We argue that online messages offer a valuable strategy that can help reduce image-based abuse and the distribution of child sexual abuse material, including by minors.
The Relationship between Exchange Rate and Stock Market Performance: Empirical Evidence from Sri Lanka
Authors: Anusha P. , Dhushanthan B. , Vinayagathasan T.
Published: June 2022

The stock market is one of the fastest-growing sectors in the world at present. Such a stock market can be seen growing in Sri Lanka as well. The performance of a stock market is affected by various factors. Among those factors, foreign market stock prices, GDP, corporate performance, and the exchange rate are important. Of these, the exchange rate is the crucial one. Data of exchange rate depict the increasing pattern over time while stock market performance shows high fluctuation in Sri Lanka. Thus, this research aims to identify the impact of the exchange rate on the performance of the Colombo Stock Exchange (CSE). For this purpose, we used price index of all stocks, exchange rate, inflation, foreign direct investment, and interest rate as the variables. We employed annual secondary data from Central Bank of Sri Lanka over the period of 1985 – 2018. The Augmented Dickey Fuller and Phillips Perron unit root tests approaches confirmed that none of the variables are I(2) which allows us to examine the long-run relationship between the variables using Auto-Regressive Distributed Lag (ARDL) bounds testing method. AIC is suggested to employ ARDL(1,1,0,4,4) model among the top 20 models. The bounds testing results detected the cointegrating relationship between the variables. Our results also suggest that there is no correlation between exchange rate and all share price indexes in the long run, whereas there is a positive relationship between exchange rate and all share price indexes in the short run. Inflation has a positive impact on all share price indexes in the long run while it does not have significant impact on all share price indexes in the short run. Moreover, the interest rate has a negative and weakly significant impact on all share price indexes both in the long run and in the short run. The Granger causality test indicates that there is a unidirectional causality between the price index of all stocks and the exchange rate. Therefore the results of this research emphasize that the exchange rate can be used as a policy tool to increase stock market performance.
理想的督導活動與效用評估—社福組織工作者觀點
Authors: 鍾武中 鍾武中
Published: June 2022

督導為確保專業服務與最佳原則的發揮，具有獨特功能性。然國內卻少有探討各項督導活動運用成效的研究，且進一步以工作者觀點檢視如對督導活動的重要性、有效性、關鍵影響力、評價差異與影響因素等議題的研究幾乎沒有。本研究以承接各地方政府社會局處服務方案的社福組織為調查單位，共222位督導者及349位社工參與。採結構性問卷以SPSS進行描述性統計、獨立樣本t檢定、單因子變異數及重要度－表現分析法（IPA）進行分析。其中，「單位類型」與「具社工師證照」是影響督導者、「年齡」是影響社工評價的關鍵要素。而「能力提升」被視為符合期待的督導活動，「行政職能」則被視為提升督導成效的關鍵要素，但具社工師證照非進（晉）用督導職務的必要條件。

 

 Supervisors have a unique function of ensuring professional service and best practices. However, few studies in Taiwan have explored the effectiveness of supervisory activities, and almost none have examined the importance, effectiveness, key influence, evaluation differences, and influencing factors of these activities from workers’ perspectives. In this study , the social welfare institutions responsible for the social service programs of various local governments as the survey units. 222 supervisors and 349 social workers were surveyed using a structured questionnaire. The statistical analyses, including descriptive statistics, independent-samples t-test, ANOVA, and importance-performance analysis (IPA), showed that “unit type” and “social work certificate” were the critical factors affecting supervisors, while “age” was the critical factor affecting the evaluation of social workers.“Ability enhancement” was regarded as a supervisory activity that meets expectations and “administrative function” as a critical factor in improving supervisory effectiveness. However, social work certificates were not a prerequisite for supervisory positions.

 
評《社企是門好生意？社會企業的批判與反思》
Authors: 鍾怡婷 鍾怡婷
Published: June 2022

本文首先介紹《社企是門好生意？社會企業的批判與反思》一書的重點內容。第1章介紹社會企業的發展路徑，及其源自新自由主義開始主導世界經濟與政治運作的背景。第2章與第3章的內容在於翻轉美化社會企業的主流論述並呈現可能帶來的隱憂。第4章到第8章則以臺灣和全球各地案例進一步探討社會弱勢者照顧與消除貧窮等議題。本書提醒我們，這些看來簡單美好並鼓吹以個人努力方式來解決問題的行動，潛藏著將社會問題去政治化、鼓勵國家退讓給市場、將公民形塑為消費者的思維邏輯，因此必須謹慎看待並深入思考它們如何面對結構性因素。本文最後提出蒙德拉貢合作社之案例與本書對話，並借鏡經濟多樣性觀點來思考商業營利與社會公平正義之間的關係。

 

This paper first highlights the contents of the book “Is Social Enterprise Good Business? Critical Thinking and Reflection.” The first chapter shows the development path of social enterprise and its context of neoliberalism. The second and third chapters discuss a reverse view of mainstream discourses of social enterprise and overlooked problems. Cases of social care and eradicating poverty issues are discussed in Chapters 4 to 8. This book reminds us that behind those simple and good problem-solving projects based on individual effort, there might be hidden ideologies of the depoliticization of social problems, encouragement of giving room to the market, and transformation of citizens into consumers. Therefore, social entrepreneurship must be treated with caution, with measures to verify if it addresses structural challenges. Finally, this paper suggests the experiences of the Mondragon Cooperative Corporation and the concept of diverse economies as another point of view to consider in the relationship between surplus creating and social justice.

 
Frequency of Depression in Caregivers of Patients with Epilepsy
Authors: Balouch Amjad Hussain , Nazir Shanza , Magsi Shoaib Ahmed , Kumar Ratan , Awan Inayatullah , Kumar Arjan
Published: June 2022

Background: Epilepsy is the neurological issue and disorder that causes fits or seizures, which are brief bursts of involuntary autonomic function or sensation caused by an excessive electrical discharge in the brain. Caregiving of such patient is a difficult experience that can have a negative impact on the caregiver's physical and mental health. Objective: To determine the frequency of depression in caregivers of patients with epilepsy Study Setting: Department of Psychiatry, Jinnah Hospital Lahore. Duration of Study: May 30, 2017 to November 29, 2017 Study Design: Cross-Sectional Study Subjects & Methods: A total of 130 caregivers of patients with epilepsy were enrolled. Hospital Anxiety Depression Scale (HADS) was use to determine the depression in caregivers of epilepsy patients who were initially non-psychiatric patients,and the cut - off point of 8 or more above in depressive subscale indicated depression. Respondents with score of 8 and above in HADS depression sub-scale was considered to have depression. Data were entered and analyzed using SPSS v22.0. Results: A total of 130caregivers of patients with epilepsy were included. Age range in this study was from 20 to 50years with mean age of 34.5±8.7years. Among 130caregivers of patients with epilepsy, 87(66.9%) were males and 43(33.1%) were females.Among caregivers of patients with epilepsy, 68(52.3%) had depression. Conclusion: Caregivers presented with high depression esteems as they didn’t have a top-quality of life. Keywords:Depression, Epilepsy, Caregivers.
Assessment of Knowledge, Practices and Self-Reported Problems Related to Halitosis among the Students of Sharif Medical and Dental College and Bakhtawar Amin Medical and Dental College
Authors: Shahid Mahnoor , Malik Wajih , Hameed Marij , Rashid Usman , Saif Sarmad , Khan Nauman Rauf
Published: June 2022

Introduction: Halitosis is the source of nuisance and can affect person’s own health. This can also create social issues and may decrease self-confidence. The main cause of large number of populations effected by this condition is lack of awareness, knowledge or non-accessibility to health care facility. Objectives: The aim of this study is to access the knowledge, practices and self-reported problems of halitosis among the students of Sharif Medical & Dental College, Sharif College of Engineering and Technology and Bakhtawar Amin Medical and Dental College Multan. Duration of Study: This cross-sectional study was conducted among students of Sharif Medical & Dental College Sharif College of Engineering and Technology and Bakhtawar Amin Medical and Dental College Multan from 1st July 2019 to 01st January 2022. Material and Methods: The data was collected using a questionnaire consisting of 13 questions includes three components i.e. knowledge, practices and self- reported problems. Practice and self -reported problems were assessed using special scoring system. Results: 500 students participated in the research program. Among all students, 69.8% had knowledge about halitosis. Responses to self-reported problems showed 7.2% of the participants suffered from halitosis. 29.8% and 30.4% reported dental caries and bleeding gums respectively. 25.6% mentioned about the dryness of mouth. 49.4% were concerned about social impact of their bad breath. Conclusion: Increasing awareness, knowledge about the cause and treatment options of this condition can improve the general health and well-being.
Nurses' Knowledge Concerning End of Life Care in Critical Care Units
Authors: Hamid Shehab Ahmed , Mohammed Tahseen R.
Published: June 2022

The study aimed to assess nurses' Knowledge toward Palliative Care of Patients end of life phase, a descriptive cross-sectional study design is carried out from the period of November 2021) to (1th February 2022). A probability simple random sampling technique Then, the number of participants in each selected hospital were determined using the sampling to each randomly selected at hospital in Dyala city in Iraq. A total of (100) nurses were working in the critical care units during the time of the study period and met the study criteria and agree to participate. Ten nurses for pilot study were excluded from the study. the result of co-relation co efficient were (79%). Study data were collected through A questionnaire was built as a data collection tool and consisted of two parts instrument. The study found results of this study showed that nurses are good knowledge (74.0%) for palliative care and toward End of life care among nurses working in Dyala city in Iraq. This study emphasizes the need to develop palliative care services. The study recommends Education or training the nurses who read the articles about palliative care. Provide evidence More attention and resources should be directed towards education and support Nurses who care for patients with palliative care needs. Keywords: Palliative Care, Critical Care Units, End of life care, End of life phase
Scenario of Antibiotic Resistance in Pakistan: A Systematic Review
Authors: Iqbal Sarwat , Bhatti Shahzad Majeed , Amir Muhammad , Zaman Qamar Uz , Raza Ayesha
Published: June 2022

Background: A rise in antimicrobial resistance and a decrease in the discovery of novel antibiotics have occurred in recent years. Pakistan is a South Asian developing nation with a high level of antibiotic resistance, which poses a serious regional and global threat. Objective: To determine the situation of antimicrobial resistance in Pakistan Methodology: In the current study the literature was reviewed systematically according to the guidelines of PRISMA. Numerous databases like PUBMED, Embase, Medline and Google scholar were reviewed to determine the prevalence of antimicrobial resistance in Pakistan in the last 10 years from 2012 to 2022. For collection of duplicate data, a standardized extractive datasheet was used. All the data was entered in Microsoft Excel 2019. Results: In the current study, a total of 82 articles were included for final analysis. Multiple drug resistant bacteria were observed in 8 (9.76%) studies while extensive drug resistant bacteria were observed in 2 (2.44%) studies. High median resistance (95% CI) was shown by E. coli to first line antibiotics. Salmonella spp showed high median resistance to ciprofloxacin (90.5%). High median resistance was observed to majority of available antibiotics by Acinetobacter spp. Pseudomonas spp were highly susceptible (86.5%) to cefoperazone-sulbactam. MRSA S. aureus was reported in 13 studies and they were highly resistant to penicillin (98%), cefoxitin (83%) and levofloxacin (80%). Conclusion: Our study concludes that antimicrobial resistance pattern of common pathogens was high against commonly prescribed antibiotics. Regularization of monitoring practices, regular local and national monitoring, molecular investigations, and particular efforts to address the risk associated with the rise in antibiotic resistance are required to combat this issue. Keywords: Antibiotic resistance; Multiple drug resistance, Extensive drug resistance
Impact the Implementation of Feto-Maternaltriage Program Upon Maternal Health Outcomes in Maternity Hospitals of Baghdad City
Authors: Muttaleb Wisam M.
Published: June 2022

Triage is a major portion of clinical hazard administration in all divisions when clinical load surpasses clinical accessibility. (Jones,K 2006). Triage is used to sort, to direct requires clinical judgments and to rapidly assess a patient and assign a priority based on clinical need. Also triage considers as a fundamental cornerstone of clinical risk management (Mackway-Jones,k 2006). triage in obstetric area become one of the latest obstetric services to emerge.( PA-PSRS 2015 ). "In the last years, OB triage become important in the OB services in most hospitals in the world and developed a triage area adjacent to the labor and delivery department (The Pennsylvania Patient Safety Advisory 2008). According to triage protocol the women should be treated according to the severity or the acuity of the case and not the time of her arrival to the outpatient clinic. Keyword: Triage, Obstetric Triage, Maternal Outcomes