bluuebunny/crossref_metadata_2025 huggingface dataset:
Antifungal Resistance in Patients with Candidemia: A Retrospective Cohort Study
Authors: Aldardeer Namareq , Albar Hadiel , Al-Attas Majda , Eldali Abdelmoneim , Qutub Mohammed , Hassanien Ashraf , Alraddadi Basem
Published: May 2019

Background

Candidemia is the most common form of invasive candidiasis. Resistant Candida blood stream infection (BSI) is rising with limitation in the development of broader spectrum antifungal agents worldwide. Our study aimed to identify rate of antifungal resistance candidemia and distribution for species, determine risk factors associated with antifungal resistance and evaluate the association of antifungal resistance candidemia with length of Intensive Care Unit (ICU) and hospital stay and with 30-day mortality.

Methods

A retrospective cohort study was conducted at King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia. Adult patients diagnosed with candidemia from January 2006 to December 2017 were included.

Results

A total of 196 BSI was identified in 94 males (49.74%) and 95 females (50.26%). C.glabrata was the most common isolated Candida 59 (30%) followed by C. albicans 46 (23%). Susceptibility data were available for 122/189 patients in which 26/122 (21%) found to have one or more antifungal resistance. C. parapsilosis isolates with available sensitivity data were 31/122 in which 10/31 (32%) were resistant to fluconazole. Risk factors significantly associated with antifungal resistance candidemia include previous echinocandin exposure (Odd Ratio (OR) =1.38; 95% Confidence Interval (CI) (1.02-1.85); P= 0.006) and invasive ventilation (OR=1.3; 95% CI (1.08-1.57); P= 0.005). Median length of ICU stay was 29 days [range12-49 days] in antifungal resistance group and 18 days [range 6.7-37.5 days] in antifungal sensitive group; Median length of hospital stay was 51days [range 21-138 days] in antifungal resistance group and 35 days [range 17-77 days] in antifungal sensitive group. Thirty- day mortality was 15 (57.7%) and 54 (56.25%) among antifungal resistance and antifungal sensitive group, respectively (OR=1.01; 95% CI (0.84-1.21); P= 0.89).

Conclusions

Our results indicate an increase in the rate of non-albicans candidemia. Candida parapsilosis resistance to fluconazole is alarming. Further studies are required to confirm this finding.
The efficiency of Islamic banks versus conventional banks: an empirical study of an emerging economy
Authors: M. Hafez Hassan , Halim Mona
Published: May 2019

The purpose of this study is to investigate the efficiency of two different banking systems operating in Egypt (Islamic versus conventional banks). A sample of 35 banks has been used to examine the technical efficiency before and after the financial crisis using data envelopment analysis model. Evaluating the technical efficiency of Egyptian banks will enable policymakers to support which banking system is more efficient to facilitate the financial inclusion and enhance the economic development.Before the financial crisis, conventional banks outperformed conventional banks with Islamic windows and Islamic banks, scale technical efficiency outperformed pure technical efficiency when analyzing conventional banks and conventional banks with Islamic windows. In terms of Islamic banks, pure efficiency outperformed scale efficiency. After the financial crisis, technical efficiency of all banks decreased. However, pure technical efficiency of Islamic banks has improved as a result of the quality of management and outperformed both conventional banks and conventional banks with Islamic windows. These results imply that Islamic banks have not been affected by the financial crisis. Therefore, the increased adoption and support of the Islamic banks in Egypt is addressed to develop the economy and push forward entrepreneurship projects, support the financial inclusion and the informal economy integration.
Oral N - Acetyl Cysteine for Meconium Ileus of Preterm Infants
Authors: Kadioglu Simsek Gulsum , Arayici Sema , Buyuktiryaki Mehmet , Okur Nilufer , Kanmaz Kutman Gozde , Oguz Serife Suna
Published: May 2019

Objective: Meconium ileus of preterm infant is a kind of intestinal obstruction. There is no standard medical treatment of meconium ileus of preterm infant. Study Design: During the study period, preterm infants under 1250 g and have clinical signs of meconium obstruction were retrospectively included in the study. In the first two days, rectal saline and metoclopramide started and if not respond these infants assigned to receive oral or rectal n-acetyl cysteine and control group remained to receive a saline enema. Results: One hundred and twenty-one infants were included in the study. Thirty-four of them received oral n-acetyl cysteine (group 1) and fifty-two had treated with rectal n-acetyl cysteine (group 2), thirty-five of them served as a control group (group 3). The mean gestational ages were 28, 28, 27 weeks and birthweights were 942, 1010, 965 grams for group 1 & 2 & 3 respectively. There was a difference between groups for reaching full enteral feedings (13 ±2, 13 ±3, 15±3, group 1 & 2 & 3 respectively, p=0.001). Conclusion: According to this study, it can be stated that orally administered n-acetyl cysteine is tolerable and as effective as rectal n-acetyl cysteine when used for MIPI.
Market ways to assess the effectiveness of real investment
Authors: Turchenko Liubov Grigorevna
Published: May 2019

The article analyzes the fundamental concepts of a market economy and investment. The calculation of the economic efficiency of investment projects, with the choice of the best investment options. There are solutions to the problem: the discovery of the essence of the modern methods of economic efficiency of investments and indicators for evaluating the effectiveness.
Análise de vinte anos de dados limnológicos e bacteriológicos nas lagoas costeiras do litoral norte do Rio Grande do Sul - Marcelino Ramos, Peixoto e Pinguela (Osório/RS)
Authors: FERMINO Fabiana Schumacher
Published: May 2019

As lagoas Marcelino Ramos, Peixoto e Pinguela fazem parte do complexo de lagoas costeiras do Litoral Norte do Rio Grande do Sul, estão situadas no município de Osório/RS e pertencem à Bacia Hidrográfica do Rio Tramandaí. São classificadas de acordo com a resolução CONAMA nº 357/2005 como sendo Classe 4, Classe 1 e Classe 1, respectivamente. A lagoa Marcelino Ramos, com ligação direta com as demais lagoas deste estudo através de um canal - recebeu carga de esgoto não tratado proveniente do município de Osório até o ano de 2015. Neste sentido o presente trabalho traz uma análise dos dados limnológicos e bacteriológicos das três lagoas costeiras avaliando oito variáveis limnológicas que são: temperatura da água, oxigênio dissolvido, demanda bioquímica de oxigênio, fósforo total, nitrogênio amoniacal, potencial hidrogeniônico e condutividade, e coliformes fecais. O objetivo foi analisar mudanças limnológicas nas lagoas estudadas ao longo de vinte anos – 1993 até 2013, assim como registrar se houve influência da lagoa Marcelino Ramos nas demais lagoas conectadas e as mudanças registradas nas estaçoes inverno e verão considerando os parâmetros estudados - temperatura da água, pH, fósforo total, nitrogênio total, DBO (Demanda bioquímica de oxigênio), nitrogênio amoniacal, OD (Oxigênio dissolvido), e bacteriológicos: coliformes fecais.
Rooting of yerba mate cuttings with different lengths
Authors: DUARTE Manoela Mendes , MIRESKI Maria Cecília , OLISZESKI Afonso , WENDLING Ivar , STUEPP Carlos André
Published: May 2019

Due to its economic, social, and ecological potential, Ilex paraguariensis A. St. Hil is considered one of the most important native forestry species in southern Brazil, needing high production of quality plants to supply consumption. Therefore, vegetative propagation is a key technique since it enables plants production with higher standard and genetic quality. Several studies have focused on defining appropriate methods for rooting yerba mate cuttings, even though the overall rooting indexes are not yet considered appropriate. Thus, the objective of this study was to evaluate the rooting, root and aerial vigor of yerba mate cuttings and determine the best cuttings length for formation of clonal plants. Twenty parent trees were pruned and after five months epimoric sprouts were collected to prepare stem cuttings with lengths of 2 ± 0.2 cm, 4 ± 0.2 cm, 6 ± 0.2 cm, 8 ± 0.2 cm, 10 ± 0.2 cm and 12 ± 0.2 cm and diameter of 0.5 ± 0.2 cm. We planted cuttings in plastic boxes filled with substrate based on carbonized yerba mate matchsticks and vermiculite. After 120 days we evaluated the percentage of rooting, number of roots per cutting, average length of the 3 largest roots per cutting, cuttings with callus, cuttings with roots and callus, mortality, sprouts emission, and leaf maintenance. Our results show that rooting and vigor of roots in yerba mate stem cuttings are influenced by cuttings length, being 10 cm cuttings the most efficient for clonal propagation of the species.
Health Status and Quality of Life of Patients Enrolled in a Specialized Refractory Angina Clinic
Authors: Bennett Noel M. , Rutten-Ramos Stephanie , Arndt Theresa L. , Garberich Ross F. , Traverse Jay H. , Poulose Anil K. , Mitchell Patricia , Storey Katelyn M. , Henry Timothy D.
Published: May 2019

As the mortality of coronary artery disease improves and the population ages, an increasing number of patients with refractory angina are not candidates for percutaneous or surgical revascularization. We evaluated the impact of a dedicated refractory angina clinic on quality of life. In 76 patients who completed the Medical Outcomes Study 36-Item Short-Form Health Survey and Seattle Angina Questionnaire at baseline and 1 year, the Medical Outcomes Study results showed the proportion of patients who rated their health as “good” or “excellent” more than doubled from baseline to 1 year (15.8% vs. 42.2%; P < .001). Similarly, the Seattle Angina Questionnaire score was significantly improved at 1 year compared to baseline (P = .025), as were angina stability (P = 0.017) and angina frequency (P = .010). In conclusion, treatment in a dedicated clinic is associated with improved quality of life in patients with refractory angina.
Physical and Numerical Modelling of Tsunami Run-up on Seawall at Sloping Beach
Authors: Sutanto Ma'ruf Hadi
Published: May 2019

Tsunami run-up on land has a large destructive power. Further studies are deemed necessary to understand the process and characteristics of tsunami run-up in coastal areas. Seawall structures can reduce the run-up of a tsunami depending on the height of the seawall crest. Physical modeling shows that seawall may significantly reduce run-up (𝑅) and inundation (𝑋𝑖). The highest reduction up to 55% where the seawall peak height is 7 cm and the water depth is 15 cm. With the same scenario in numerical modeling, the percentage reduction is 67.53%. The highest inundation (Xi) in the scenario without seawall structure is 6.081 m when the initial water depth (d0) equals to 30 cm. The result of the numerical model for the same scenario is 6.970 m. Seawall as tsunami mitigation structure is only effective when the tsunami wave is relatively low compared to the seawall height (H/ sw). Reduction percentage > 25%, with conditions that H/ sw is < 0.856 (physical model) and < 0.802 (numerical model).
Horizontal Vibrations of Embedded Foundation in Multi-Layered Poroelastic Soils
Authors: Senjuntichai Teerapong
Published: May 2019

In this paper, the dynamic response of rigid foundations of arbitrary shape embedded in multi-layered poroelastic soils subjected to time-harmonic horizontal loading is presented. The soil-structure interaction problem is investigated by employing a discretization technique and flexibility equations based on the influence functions obtained from an exact stiffness matrix scheme. The present solution scheme is verified with relevant existing solutions of rigid foundations on homogeneous elastic and poroelastic media. A selected set of numerical results are illustrated to portray the influence of various parameters, namely, frequency of excitation, poroelastic material parameters, foundation shapes, embedded depth, and the supporting soil systems, on non-dimensional horizontal compliances of rigid foundations.
EXPERIENCIAS DEL CUIDADOR PRIMARIO EN LA ATENCIÓN A UN FAMILIAR CON ALZHEIMER
Authors: Montoya García Yazmín , Guillén Cadena Dulce María
Published: May 2019

Introducción: Con el incremento de la expectativa de vida, la incidencia de la enfermedad de Alzheimer va en aumento. Se manifiesta por una fuerte pérdida de la memoria, disminución de la capacidad para realizar las tareas cotidianas, alteraciones del juicio, desorientación, cambios de personalidad, y pérdida de patrones lingüísticos. La muerte del individuo ocurre en un plazo de 6 a 12 años después de iniciada la enfermedad. Durante el desarrollo de la enfermedad, el paciente se vuelve más dependiente de quien adquirió el rol de su cuidador primario, que a menudo suele ser el familiar más directo: hijo(a), esposo(a), hermano(a).Objetivo Interpretar las experiencias vividas de la cuidadora primaria con un paciente con Alzheimer. Metodología Investigación cualitativa, de orden fenomenológico, donde se entrevistaron a 5 cuidadoras primarias de familiares con Alzheimer, que se contactaron en la Fundación Alzheimer I.A.P “Alguien con quien contar”. Los

datos obtenidos se analizaron y codificaron para su posterior categorización y subcategorización.

Hallazgos: La experiencia del cuidador conlleva un transcurso de pasos, en la fase inicial se refiere a los motivos para iniciarse en el cuidado: obligación moral, lazos familiares y afectivos. Y en el transcurso se adquieren habilidades para realizar actividades de cuidado, se hacen evidentes situaciones de crisis que repercuten en la esfera biopsicosocial del cuidador.

Conclusiones: Podemos ubicar a las cuidadoras como un grupo vulnerable a la sobrecarga, estrés y exclusión, que necesitan apoyo multidisciplinario para contribuir al mantenimiento de su calidad de vida.
Movilidad estudiantil. "Un viaje hacia el aprendizaje".
Authors: Navarrete Salas Brenda , Mayor Rangel Lady Laura , Rangel Camacho Noemi Susana , González García Zaira Pilar , Zavala Torres Vanessa Guadalupe
Published: May 2019

Introducción: Esta investigación de tipo descriptivo, cualitativo y fenomenológico, aborda  las vivencias de 5 estudiantes universitarias de la licenciatura en enfermería pertenecientes al programa de movilidad estudiantil de la Facultad de Estudios Superiores Iztacala UNAM.

La importancia de la presente investigación surge   a partir de la necesidad de  conocer a fondo el proceso de movilidad, debido a que compañeras que vivieron esta experiencia expresan que su estancia en el extranjero no fue fácil, argumentando que la universidad no les proporciona las facilidades necesarias para su estancia, además de enfrentarse  a cambios que implican modificar su estilo de vida para incorporarse a una nueva sociedad, cultura, costumbres,  idioma etc. Estos cambios conllevan a que se presenten sentimientos encontrados que repercuten en el estado de ánimo y desempeño académico del estudiante. Metodología: Se diseñó un instrumento de valoración para la recolección de datos a través de una entrevista, una vez obtenida la información se codificó y se categorizó.

 Hallazgos: Las vivencias de las estudiantes se describen en las siguientes categorías: Experiencias, Aprendizajes, Adaptación y Sentimientos – Emociones, conformadas a la vez por subcategorías como: crecimiento profesional, independencia personal, dificultad de adaptación al sistema de estudios.  Conclusiones: No existe una buena coordinación  entre las instituciones que establecen los convenios de movilidad estudiantil. Además el proceso de adaptación se hace difícil debido a que no cuentan con la información necesaria para poder incorporarse al país donde llegan y a la  universidad.
BIOÉTICA: UNA MIRADA DESDE LA DOCENCIA EN ENFERMERÍA
Authors: Acevedo Peña Margarita , Castañeda Rivas Tonantzin Guadalupe
Published: May 2019

Se busca realizar una reflexión sobre la manera en que se aplica la ética y la bioética en la docencia en enfermería, como parte de formadores de futuros profesionales en enfermería. Es responsabilidad del docente no sólo transmitir conocimientos, sino ser ejemplo de la aplicación de la ética y bioética en la vida cotidiana a través del ejemplo, logrando una mejor formación del egresado para que pueda brindar cuidados de calidad, y calidez, que tanto merece y reclama la persona.
NARRATIVA DE ENFERMERÍA: UNA EXPERIENCIA SIGNIFICATIVA EN MEDIO DE LA ADVERSIDAD
Authors: Varela Lodoño Luz Estrella , Salazar Maya Ángela María
Published: May 2019

...
TEORIZAR Y DIAGNOSTICAR EN ENFERMERÍA: LA EVOLUCIÓN DEL PENSAMIENTO ENFERMERO
Authors: Alvarado Romero Thalía , Godínez Rodríguez María De los Ángeles
Published: May 2019

En la actualidad enfermería se encuentra en

el paradigma de la transformación, pero se hace

necesario preguntarnos si esa transformación es

real, si en verdad estamos avanzando en dirección

de los objetivos planteados o nos encontramos

en una pausa autoimpuesta tratando de asimilar

nuestras capacidades y preguntándonos ¿qué

somos? y ¿hacia dónde vamos? Este paradigma

sitúa a la enfermería en un punto evolutivo superior,

una situación dinámica y compleja, un proceso

de transición, revalidación y transformación

disciplinar que va de la mano de una transformación

científica que busca la trascendencia del cuidado.

Para trascender en el cuidado, el enfermero tiene

una doble labor; producir literatura científica y

consumirla pues la producción y el acúmulo de las

teorías y los artículos en enfermería no sirven si no

se llevan a un plano práctico, cuando no consumimos

lo que producimos; estamos ocasionando una fuga

de conocimiento y un rezago en la actualización y

transferencia de éste. Dado que en la actualidad la

evolución teórica del conocimiento que tenemos del

cuidado ha revolucionado de manera irreversible la

práctica y los sistemas de educación de enfermería,

se vuelve fundamental utilizar todos los recursos

con los que contamos, valorar los esfuerzos en la

producción científica de enfermería y reconocer

que la investigación sin importar el paradigma que

sigue, provee conocimiento y fortalece el desarrollo

de la enfermería como disciplina y como ciencia.
Proceso de Atención de Enfermería aplicado a la comunidad de "Tecolotla" municipio de Mixtla de Altamirano, Veracruz.
Authors: Palomino Morales Lorena Guadalupe , Plata Reyes Karla Karina , Lobera López Juan José
Published: May 2019

Este proceso enfermero fue aplicado en la

comunidad de Tecolotla, perteneciente al Municipio

Mixtla de Altamirano, Veracruz, en colaboración

con una organización humanitaria global, cuya sede

se encuentra en Estados Unidos, que promueve

la protección y bienestar de la niñez, fomenta el

desarrollo transformador en comunidades que viven

en extrema pobreza. Objetivo: Aplicar el proceso de

enfermería en la comunidad de Tecolotla a través

de educación para la salud que lleve a conductas

de promoción y prevención de enfermedades

infecciosas y crónico-degenerativas, autocuidado

y mantenimiento de la salud en la población

infantil y adulta. Metodología: Se aplicó durante

los meses de marzo a julio del 2016, el muestreo

fue no probabilístico por conveniencia captando

a 195 personas. Se hicieron visitas domiciliarias

aplicando una cédula familiar, derivando de éstas el

análisis y resultado de los datos, los cuales ayudaron

a establecer diagnósticos de enfermería de acuerdo

a las taxonomías Diagnósticos enfermeros:

Definiciones y clasificación (NANDA), Clasificación

de Resultados de Enfermería (NOC), y Clasificación

de Intervenciones de Enfermería (NIC) elaborando

e implementando dos programas educativos con

la finalidad de prevenir enfermedades infecciosas

y crónico-degenerativas. Se evaluó el programa

“Sonrisas y manos limpias” dirigido a 72 niños

de manera demostrativa sobre las técnicas de

cepillado dental y lavado de manos; el programa “Si

vivir quieres, prevenir debes” enfocado en adultos

se evaluó con un cuestionario obteniendo una

calificación final de 8.08 puntos. Conclusiones: Los

niños replicaron en el ambiente familiar y escolar lo

aprendido; los adultos adquirieron conocimientos

que fortalecieron sus conductas saludables.
APLICACIÓN DE UN PROGRAMA DE ELECTROESTIMULACIÓN PARA LA PÉRDIDA DE GRASA CORPORAL EN MUJERES
Authors: Guzmán Quintana Karina Yazmín , Granados Carrillo José Roberto
Published: May 2019

Actualmente México encabeza el listado de países con sobrepeso y obesidad en su población adulta, de modo que 7 de cada 10 adultos presentan este padecimiento, por lo que es considerado un problema de salud pública difícil de combatir a pesar de las estrategias implementadas para ello1. Es importante

el papel del profesional de enfermería hacia esta población, ya que se encarga del control y seguimiento de los pacientes con esta enfermedad, siendo capaz

de diseñar e implementar programas de nutrición y actividad física que permitan mejorar la calidad de vida del paciente. El objetivo fue aplicar un programa

de electroestimulación encaminado a favorecer la pérdida de grasa corporal en mujeres de 30 a 40 años. Es una investigación de tipo experimental (experimental puro), prospectiva, longitudinal y analítica. El nivel de la investigación es aplicativo. Se seleccionaron dos grupos de mujeres entre 30

y 40 años que realizan actividad física: Grupo experimental con 9 mujeres y grupo control con 10

mujeres. Las mediciones se realizaron diariamente a

través de los instrumentos para valoración y de una

cédula de cotejo. Se aplicó el programa durante 7

semanas, obteniendo mediciones basales (2 semanas)

y mediciones experimentales (5 semanas) aplicando 3

sesiones por semana con una duración de 30 minutos.

Los resultados demostraron una disminución

significativa en el porcentaje de grasa corporal, índice

cintura-cadera y el pliegue cutáneo de la pantorrilla,

es decir, 3 de las 12 variables estudiadas. Lo que

resulta favorecedor en el bienestar biológico y físico

de las participantes.
EL CUIDADO, ENTRE EL HUMANISMO Y CIENCIA
Authors: Cárdenas Vargas Jordi Omar
Published: May 2019

Hoy en día los avances tecnocientíficos parecen

establecer una idea de progreso, sin embargo, ¿Hay

progreso?, ¿O es que acaso dicho avance no tiene

implicaciones humanas?, de ser o no así, ¿Cuáles

serían las repercusiones?

Esta reflexión sería imposible de responder en un

solo escrito, por tanto, se pretende indagar acerca

de los alcances que dicho progreso tiene respecto

a la salud y el cuidado humano, y cómo la práctica

profesional lo aborda para solucionarlo. De tal forma,

es indispensable delinear cómo una cosmovisión

cientificista promete un progreso con sus hallazgos

y aplicaciones técnicas y tecnológicas, pero lejos

de lograrlo, acrecienta solo la progresión de un

deshumanizado devenir, en el que el ser humano se

vuelve un objeto simple, engranado mediante el poder

biopolítico.

Lo anterior forma parte de la construcción de una

sociedad llena de personas que van perdiendo incluso

su sentido de vida, su ética; imponiéndose un tener

sobre un ser, en donde se puntualizan nuevos hábitos

y edifican estilos de vida que se legitiman como

nuevas costumbres. Este ser humano individualizado

y alienado se ha descuidado de lo imprescindible. Por

tanto, es menester que se retome el ser, y aquellos

que se profesionalizan para el cuidado humano, no

vean un simple objeto de estudio, sino, que este vea de

manera empática a cada persona, que padece, siente,

sufre y goza de la inquietante pero extraordinaria

vida, es encaminar un progreso sin olvidar al ser y

realizarse como persona humana.
Una descarga de emociones: "Vivir con epilepsia"
Authors: Vázquez Mata Claudia Viridiana , Ruíz López Sandra Viridiana , Carapia Fierros Paloma , Cruz Vera Juan José , Guillén Cadena Dulce María
Published: May 2019

Introducción: En México, la epilepsia es la segunda enfermedad neurológica más recurrente, de acuerdo a la Organización Mundial de la Salud es una afección crónica recurrente, caracterizada por una hiperactividad sincrónica e intermitente de las células cerebrales, que presentan descargas eléctricas; la estigmatización de esta enfermedad, provoca una serie de repercusiones a nivel biológico, psicológico o social en la persona y familia. Objetivo: Explicar el significado de la epilepsia en vivencias de pacientes del grupo “Aceptación de Epilepsia” pertenecientes al Hospital 20 de Noviembre del ISSSTE. Metodología: Investigación cualitativa fenomenológica interpretativa, la obtención de datos se realizó a través de una entrevista realizada en grupo, participaron ocho pacientes del Grupo “Aceptación de Epilepsia” captados por medio del muestreo total de población, sexo indistinto, que hayan vivido la enfermedad por tres años, y contaran con control médico y farmacológico. Hallazgos: Se encontraron temas relacionados con sentimientos y emociones negativas y positivas, dificultad en las relaciones interpersonales, con la sociedad y familia, pues los limitan a tener una vida de calidad. Conclusión: La epilepsia lesiona la autoestima, la independencia y relaciones interpersonales de quien la padece, lo cual favorece la sobreprotección familiar impidiendo al paciente llevar una vida cotidiana en la cual pueda satisfacer sus expectativas y anhelos. 
Áreas de oportunidad y el rol del investigador en Enfermería
Authors: Alonso Ricardez Abraham , Cuevas Guajardo Leticia , Valera Mota Myrna Miriam , Alonso Trujillo Javier , Regalado Ruíz Luis Alberto
Published: May 2019

Introducción. El objetivo de este ensayo consiste en reflexionar sobre el significado que tiene el rol de investigador(a) en enfermería y el descubrimiento de áreas de oportunidad para los estudiantes y para el personal de enfermería profesional. Existen elementos que un investigador con formación en enfermería debe tomar en cuenta para la elección de un tema de investigación, como lo son, por ejemplo, la observación constante de los fenómenos, la factibilidad de realizar la investigación y la utilidad que ésta tendrá en la sociedad. Desarrollo. Se realizó un estudio documental exploratorio para el desarrollo del presente ensayo. Existe evidencia que muestra que existe poco interés en ampliar los conocimientos científicos en enfermería1; sin embargo, existen una diversidad amplia de temas en los que enfermería puede contribuir de manera sustancial que van desde proponer cambios y alternativas de transformación orientados a la intervención, hasta la aplicación del conocimiento teórico y práctico para el desarrollo de tecnologías médicas, y que por ende, involucran la participación de enfermería en equipos multidisciplinarios en salud2. Conclusiones. En enfermería existe un amplio espectro de temas de investigación que puede implementarse, no sólo en el área asistencial, sino también en otras áreas del quehacer de enfermería. Por tanto, es una oportunidad importante para los profesionales de enfermería la producción de conocimiento científico de alto impacto para la mejora de la praxis profesional y en consecuencia, de los sistemas de salud en México. 
Analisis Perbedaan Faktor-Faktor yang Berpengaruh Terhadap Keberadaan Jentik Aedes Aegypti di Kelurahan Endemis dan Kelurahan Sporadis Kota Banjarbaru
Authors: Fakhriadi Rudi , Asnawati Asnawati
Published: May 2019

Dengue Fever (DF) or Dengue Haemorrahagic Fever (DHF) is one of the few infectious diseases that become health problems in the world especially developing countries. Data obtained from Banjarbaru City Health Office found a trend of increasing the incidence of DHF. Last data of 2015 was recorded as many as 182 cases. Of 20 urban villages in Banjarbaru there are 10 outbreaks that menajdi Endemis dengue disease area and 10 outbreaks that became sporadic areas of dengue disease. Dengue fever prevention has a fairly complex problem. But the best way to prevent this disease is by eradicating mosquito larvae The purpose of this study is to see the factors that affect the presence of larva Aedes aegypti in endemic areas and sporadic dengue areas. The design of this study was observational analytic using cross sectional method with 100 samples of house at endemic and sporadic dengue. Data analysis was bivariate with chi-square and multivariate test with logistic regression test with 95% confidence degree. The result of bivariate and multivariate test showed that in the endemic area the related factors were knowledge and community action regarding EMN with larva Aedes aegypti (p <0,05). In the sporadic area of ​​DHF the corresponding variable was community education with the presence of larvae Aedes aegypti (p <0.05). While other variables are not significantly related to the presence of larva Aedes aegypti in endemic and sporadic dengue areas.
Gambaran pengetahuan, perilaku dan pencegahan malaria oleh masyarakat di Kabupaten Maluku Tenggara Barat dan Maluku Barat Daya
Authors: Sandy Semuel , Ayomi Ivon
Published: May 2019

Kabupaten Maluku Tenggara Barat dan Maluku Barat Daya merupakan salah satu daerah endemis malaria di Provinsi Maluku. Penelitian bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian malaria antara lain pengetahuan, aktifitas masyarakat, keberadaan habitat nyamuk dan pengunaan kelambu. Desain penelitian potong lintang, sampel diambil secara purposive, dan pengambilan data dilakukan dengan wawancara. Analisis data secara deskriptif dan bivariat non parametrik (Uji Chi Square dan Uji Fisher ). Hasil penelitian faktor-faktor yang berhubungan dengan pencegahan malaria pada masyarakat di Kabupaten Maluku Tenggara Barat dan Maluku Barat Daya antara lain: pengetahuan masyarakat tentang gejala penyakit malaria OR=10,523 (p=0,002), informasi tentang malaria dari petugas kesehatan OR=7,302 (p=0,003) dan aktifitas masyarakat di kebun pagi hari (pukul 05.00) dan sore hari (pukul 18.00) OR=3,685 (p=0,007).
Evaluasi Program Pencegahan dan Pengendalian Rabies dalam Rangka Menuju Sumatera Utara Bebas Rabies 2020
Authors: Sitepu Frans Yosep , Depari Elpiani , Afriani Afriani , Sianturi Christina
Published: May 2019

Rabies merupakan masalah kesehatan masyarakat di Sumatera Utara. Tujuan dari program pencegahan dan pengendalian rabies adalah untuk mencapai Sumatera Utara bebas rabies tahun 2020. Penelitian ini merupakan penelitian observasional dengan desain cross sectional dengan mengumpulkan dan menganalisis laporan bulanan dan tahunan kasus rabies di Sumatera Utara sejak tahun 2007-2017. Evaluasi dilakukan terhadap seluruh proses program pencegahan dan pengendalian rabies. Hasil didapatkan bahwa pelaksanaan program pencegahan dan pengendalian rabies di Sumatera Utara belum berjalan optimal, seperti pelaksanaan surveilans epidemiologi, pelacakan kasus, tata laksana kasus di fasilitas pelayanan kesehatan, masih kurangnya partisipasi masyrakat, kurangnya rabies center di kabupaten/kota, serta kurangnya kerja sama antara dinas kesehatan dan dinas peternakan kabupaten/kota. Program pencegahan dan pengendalian rabies di Sumatera Utara belum berhasil dalam menurunkan kasus lyssa, masih terdapat 9 kabupaten/kota yang selama 2 tahun terakhir memiliki kasus lyssa. Disarankan lebih meningkatkan kerja sama lintas sektor dan program untuk mencapai Sumatera Utara bebas rabies 2020.
Analisis Deskriptif Potensi Terinfeksi Filariasis Pada Masyarakat Di Kabupaten Aceh Utara
Authors: Yulidar Yulidar , Zulhaida Andi
Published: May 2019

Analisis potensi terinfeksi filariasis pada masyarakat di Kabupaten Aceh Utara secara deskriptif bertujuan untuk mengetahui besarnya peluang masyarakat terinfeksi oleh filariasis. Penelitian ini merupakan penelitian analisis data sekunder secara deskriptif yang dilakukan selama 1 bulan yaitu pada bulan September 2017. Hasil analisis data menunjukkan bahwa peluang terbesar potensi terinfeksi filariasis dari 300 penduduk yang diperiksa adalah di Kecamatan Baktiya yaitu mencapai 7% (21 penduduk), di kecamatan Nisam yaitu 4,67% (14 penduduk), di  Kecamatan Lhok Beuringin dan Lhoksokun yaitu 2,67% (8 penduduk), pada masyarakat di Kecamatan Seunudon yaitu 2,33% (7 penduduk) dan  masyarakat di Kecamatan Kuta Makmur yaitu 2,00% (6 penduduk) sedangkan yang lainnya di bawah 2,00%.
Profil Penderita Tuberkulosis Paru Di Tiga Puskesmas Wilayah Kerja Kabupaten Pidie Propinsi Aceh
Authors: Hadifah Zain , Manik Ulil Amri , Zulhaida Andi , Wilya Veny
Published: May 2019

Tuberkulosis adalah penyakit menular yang disebabkan oleh mycobacterium tuberculosis dan menjadi ancaman bagi kesehatan. Jumlah kematian oleh penyakit ini mencapai 2 juta jiwa setiap tahunnya di seluruh dunia. Indonesia termasuk satu dari lima negara dengan kasus tuberkulosis terbanyak terutama tuberkulosis paru. Salah satu propinsi di Indonesia dengan kasus tuberkulosis paru tertinggi adalah Aceh yaitu di Kabupaten Pidie. Penelitian ini bertujuan untuk mengetahui bagaimana profil penderita tuberkulosis paru di Kabupaten Pidie. Lokasi penelitian adalah Puskesmas Kota Sigli, Puskesmas Mutiara Timur dan Puskesmas Delima pada bulan Oktober dan Nopember 2013 dengan pendekatan cross sectional. Sebanyak 20 responden yang dijadikan sampel merupakan penderita tuberkulosis paru dengan BTA (+) yang datang berobat maksimal 3 bulan ke puskesmas. Responden diwawancarai dengan kuesioner terstruktur. Pengamatan lingkungan sekitar rumah responden mencakup pengukuran kelembaban dan pengamatan langsung disekitar rumah. Hasil penelitian menunjukkan bahwa responden terbanyak adalah laki-laki pada usia produktif dengan status kawin dan pendidikan terbanyak adalah tamat SMA. Penghasilan keluarga setiap bulan di bawah Rp. 1.550.000,00. Jumlah anggota keluarga sebagian besar diatas 4 orang. Kelembaban dalam ruangan sudah baik, tetapi lingkungan disekitar rumah 55 % kumuh.
A NEW RECORD FOR TURKEY’S MYCOBIOTA FROM AN INTERESTING HABITAT IN THE MUGLA PROVINCE: Hortiboletus bubalinus (OOLBEKK. & DUIN) L. ALBERT & DIMA
Authors: ALLI Hakan , TEVLİM Gülçin , ŞEN İsmail
Published: May 2019

In this study, fungal samples collected in Mugla province were identified as Hortiboletus bubalinus (Oolbekk.&Duin)L. Albert & Dima and recorded for the first time for the Turkish mycobiota. Short description, photographs, locality, collection date and ecological features of this newly reported species was also provided.
Burkholderia cenocepacia bacteremia in the oncology clinic: clinical features and outcomes
Authors: Kurmukov I. A. , Pronina A. M. , Kashiya Sh. R. , Bagirova N. S. , Dmitrieva N. V. , Grigor’yevskaya Z. V. , Petuhova I. N. , Tereshchenko I. V.
Published: May 2019

Aim of the study: To determine clinical course of Burkholderia cenocepacia bacteremia and outcomes in patients receiving cancer therapy.

Materials and methods: We indentified 10 adult patients with culture-verified catheter-related Burkholderia cenocepacia bacteremia. Pathogens were identified with protein mass spectrometry of bacteria cells. Testing for the «Microscan WalkAway 40/96 Plus» (Germany) did antibiotic sensitivity or «VITEK 2» (France).

Results: In the majority of cases course of bacteremia was indolent; this fact precluded its rapid identification with standard procedures for diagnosing bloodstream infection. All patients developed fever but we revealed neither leukocytosis nor leucopenia which could be attributed to active infection. However, antibiotic treatment was initiated during the 24 h after the first signs of infection in all cases. In one patient bacteremia was complicated with septic shock. We revealed that Burkholderia cenocepacia was able to form biofilms and persist in implanted venous port systems after treatment and in order to eradicate the pathogen venous catheters had to be removed despite effective antibacterial treatment. Initial treatment was prescribed empirically and further antibacterial treatment was adjusted based on sensitivity testing results in 7 patients. Burkholderia cenocepacia eradication rate was 100% and all patients were cured and were able to continue prescribed cancer therapy afterwards.

Conclusion: given to the low frequency of Burkholderia cenocepacia sporadic infections, clinicians must be aware of the possibility of drugs and medical supplies contamination with this pathogen. If one reveals ≥1 case of Burkholderia cenocepacia-associated infection the internal investigation must be initiated. Empiric antimicrobial therapy widely prescribed to treat febrile neutropenia in cancer patients is effective in these cases. However, it cannot eradicate the pathogen from inner lumen of implanted venous catheters. Identification of the possible pathogen in blood cultures and antibiotics sensitivity testing using microbiological analyzers prompts the diagnosis of bacteremia and prescription of most effective therapy
Clinical case of combined infectious pathology (Varicella-Zoster and hantaan hemorrhagic fever) in patient with disseminated psoriasis
Authors: Svistunova N. V. , Baranova I. P. , Zykova O. A. , Kurmaeva D. U.
Published: May 2019

The article describes in detail the clinical case of a severe course of a combined viral disease (Varicella-Zoster, Hantaan Hemorrhagic Fever), complicated by bilateral interstitial pneumonia, cerebral edema, and disseminated vascular coagulation syndrome, developed in an immunocompromised patient during the treatment period of exacerbation of a background disease (plaque psoriasis, progressive stage) with a cytostatic drug. The role of the main and associated diseases (pathogenetic mechanisms of comorbidity), specificly, hantavirus infection and psoriasis, as co-factors in the formation of an unfavourable course of varicella-zoster in an adult, is discussed. An example of an individual approach to the patient, a comprehensive diagnosis and rational treatment that contributed to a favorable outcome of the disease is given.
Plasmacytoid dendritic cells and their role in the immunopathogenesis of viral infections for example hepatitis B
Authors: Khodzhibekov R. R. , Khokhlova O. N. , Reizis A. R. , Kozhevnikova G. M.
Published: May 2019

A new approach in understanding the mechanisms of immune response in viral hepatitis is the discovery of a unique type of immune cells – plasmocytoid dendritic cells (pDCs). Plasmocytoid dendritic cells (pDCs) are cells of lymphoid origin and morphologically resemble plasma cells. Functionally, they are professional IFN-a-producing cells that play an important role in antiviral immune response. Data on the mechanisms of PDCs participation in hepatitis B virus infection are few and contradictory. In chronic HBV infection, the role of pDCs remains mysterious and poorly understood with conflicting circulating blood pDCs results that show differently that they are not affected or reduced. However, functional disorders of pDCs were observed in patients with chronic HBV infection. The establishment of these mechanisms, as well as the search for the cause of hepatitis B virus latency and the formation of chronic infection remains one of the important and promising areas of scientific activities today.
Research on management strategy of coordination behavior of task conflicts in in-service thermal power unit operation based on big data modeling
Authors: Liu Ying , Hu Long
Published: May 2019

With the development of the internet and information technology, the in-service thermal power unit is facing more challenges, and the innovation of the operation and management mode of the in-service thermal power unit is urgent and necessary. From the perspective of work conflict, this paper constructs a multi-objective genetic algorithm, which introduces big data modelling technology into the management innovation of in-service thermal power units. The algorithm solves the relationship between various operating entities in active thermal power units through functions. In order to get the optimal solution for vehicle distribution. Firstly, the contingency theory is introduced into the innovative design scheme of the in-service thermal pow?er unit information system to optimize the management decision-making distribution path in the big data environment, design the multi-objective genetic algorithm steps, construct the non-dominated set, and combine the target cross-variation operations. The genetic sub-categories are jointly derived, and then the relationship between the parties in the management and decision-making innovation management activities of the in-service thermal power units is solved. The experimental results show that the shortest running time of the algorithm during the experimental operation is 0.56 seconds, and the longest running time is 2.48 seconds. The average running time in the whole process is less than 1 second, which meets the actual demand. The genetic algorithm can help the in-service thermal power unit. Reasonable arrangements for managing the delivery route of the decision-making fleet. The research in this paper has implications for the management innovation of in-service thermal power units in the information environment, and further expands the application field of big data modelling, which has practical significance.
Transient thermal characteristic analysis and charging state estimation of lithium batteries for Automated Guided Vehicle during discharge
Authors: Pian Chunyuan , Liu Junfeng , Zhao Hongzhi , Zhang Liwei
Published: May 2019

The lithium batteries and their health management for automated guided vehicle power supply system are studied in depth in this paper. First, the transient heat generation for the discharge process of a lithium battery will cause it to work in an unhealthy state and non-linear conditions, seriously affecting the life expectancy. The thermal behavior for lithium battery discharge is studied in depth, and a reliable thermal model is constructed to provide a theoretical basis for designing a lithium battery health management system. Secondly, the accurate and reliable residual state estimation of the lithium battery cannot only provide visualized battery residual capacity, but also reflect the aging status of the lithium battery and other related information, and is one of the important functions to ensure the healthy operation of the lithium battery pack. A new support vector machine is proposed on account of the analysis of the equivalent circuit model of lithium battery, which combines genetic algorithm with particle swarm optimization to enhance the parameters of hybrid kernel function, to analyze accurately the charging status. Finally, the state-of-charge simulation of lithium batteries with variable current discharge is conducted, which proves that the support vector machine algorithm proposed in this paper can accurately judge the charging state of lithium batteries.
Design and application of heating metering and monitoring system based on cloud platform
Authors: Du Heng , Yang Juncheng
Published: May 2019

With the scale of equipment needed to be managed in heat metering monitoring system becoming larger, how to realize simple management and ensure scalability is a problem that needs to be studied. Based on the comprehensive application of information and communication technology, this paper studies and expounds the intelligent management of heat metering based on cloud platform, and analyses and plans the intelligent management platform of heat metering. It is convenient for heating companies to monitor the status of the site, find problems in time and deal with them. It realizes user addition and management and facilitates business expansion. By promoting rational consumption of heat energy, the intelligent management platform of heat metering can realize energy saving, environmental protection, fair trade and make the best use of everything.
Review: Hepatoprotector Compounds in Plant Extracts
Authors: ZAIN DICHY NURYADIN , Amalia Riezki , Levita Jutti
Published: May 2019

Many plants have been reported to possess hepatoprotective activity. The mechanism has not yet been revealed, but it was predicted due to the antioxidants that could prevent the formation of free radicals produced by hepatotoxins. Of the 30 plants studied, Crocus sativus gave the largest hepatoprotector activity at a dose of 20 mg / kg, followed by Uncaria gambier Roxb. with a dose of 30 mg / kg and Melastoma malabathricum Leaf at a dose of 50 mg / kg. Keywords: Liver, CYP450, antioxidant, free radicals
USE OF SODIUM TETRAPHENYL BORON FOR FABRICATION OF POTENTIOMETRIC MEMBRANE SENSOR FOR THE ASSAY OF OLANZAPINE IN PHARMACEUTICALS AND HUMAN URINE
Authors: NAGARAJU RAJENDRA PRASAD
Published: May 2019

Olanzapine (OLP), chemically known as 2-Methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene, is an atypical antipsychotic drug. It is used for the treatment of schizophrenia and bipolar disorder. A new simple and selective membrane based potentiometric sensor was developed for potentiometric determination of olanzapine. The membrane was constructed using an ion-pair of OLP and sodium tetraphenyl boron in dioctyl phthalate and PVC. The membrane provides good linear Nernstian response covering relatively wide concentration range of 4 × 10-6 - 1 × 10-2 M OLP over pH range of 2.6-7.8. The detection limit for the developed sensor was found as 2.02 × 10-6 M. The response time of developed sensor is <10 s for the range of determination. The sensor showed good selectivity for OLP in the presence of various cations, anions and other organic molecules. The membrane was successfully applied in direct potentiometric determination of OLP in tablets. The percentage recovery of OLP, ranged from 96.2 to 99.68% with a mean standard deviation <5% indicates the adoptability of sensor for the direct estimation of OLP in pharmaceuticals. The developed sensor was used to determine OLP in spiked human urine sample and the satisfactory results were obtained.
In situ Synthesis of PANI/CuO Nanocomposites for Non-Enzymatic Electrochemical Glucose Sensing
Authors: Rahman Gul , Rahman Mustifuz Ur , Najaf Zainab
Published: May 2019

We report the in situ synthesis of polyaniline/copper oxide (PANI/CuO) nanocomposites and their characterization as electrocatalyst for non-enzymatic electrochemical glucose detection. Copper oxide (CuO) nanoparticles were prepared by wet chemical precipitation method followed by thermal treatment while the composites of PANI and CuO were synthesized by in situ chemical polymerization of aniline with definite amount of CuO. X-ray diffraction (XRD) results revealed that the composites are predominantly amorphous. The composite formation was confirmed by fourier transform infrared (FTIR) and UV-Vis spectroscopy analysis. The surface morphology was greatly altered with the amount of CuO in composite structure. PANI/CuO nanocomposites were coated on copper substrate to investigate their electrocatalytic activity for glucose sensing. PANI/CuO with 10 wt. % CuO exhibited good response towards electrochemical glucose oxidation.
Vulnerability Assessment: A Geospatial Bio-accessibility Approach Using Polycyclic Aromatic Hydrocarbons Concentration of Soils in Lagos, Nigeria.
Authors: Fatunsin Oluwatoyin T. , Adetunde Oluwasegun T. , Olayinka Kehinde O.
Published: May 2019

Cancer is on the increase globally. Cancer could be associated with hazards from anthropogenic activities. This study attempted to determine the site-specific potential human risks from polycyclic aromatic hydrocarbons (PAHs) in sites of different socioeconomic human activities from soils across Lagos metropolis in Nigeria by including a geographic information system (GIS) approach. A Human Simulation Test method was used to determine bio-accessibility for 16 priority PAHs. This was then spatially modelled using a GIS. The spatial vulnerability index for cancer developed show some variation within the study area from 0.2 – 0.0002 all falling below the normal exposure risk level of 1.0. The vulnerability to cancer based on different anthropogenic activities assessed were within the acceptable risk levels. However, it is important to reduce human exposure to even low concentrations of bio-accessible PAHs due to their tendency to bio-accumulate in plants, humans and other organisms.