bluuebunny/crossref_metadata_2025 huggingface dataset:
Health-Related Quality of Life and Survival Outcomes of Pediatric Patients With Nonmetastatic Osteosarcoma Treated in Countries With Different Resources
Authors: Bishop Michael W. , Advani Shailesh M. , Villarroel Milena , Billups Catherine A. , Navid Fariba , Rivera Cecilia , Quintana Juan A. , Gattuso Jami S. , Hinds Pamela S. , Daw Najat C.
Published: March 2017

Purpose

Health-related quality of life (HRQOL) improves throughout treatment of patients with nonmetastatic osteosarcoma. We compared HRQOL for patients in the United States and Chile treated on an international trial (OS99) with polychemotherapy and surgery, and we assessed the relationships among HRQOL measures, event-free survival (EFS), and overall survival (OS).

Materials and Methods

Patients with newly diagnosed, localized osteosarcoma and their parents completed three HRQOL instruments (PedsQL v.4, PedsQL Cancer v.3, and Symptom Distress Scale [SDS]). Data were collected at four time points throughout therapy. Repeated measures models were used to investigate the effect of treatment site on instrument scores. The log-rank test examined the impact of treatment site on survival outcomes, and Cox proportional hazards regression models evaluated baseline HRQOL measures as predictors of EFS and OS.

Results

Of 71 eligible patients, 66 (93%) participated in the HRQOL studies in the United States (n = 44) and Chile (n = 22). The median age was 13.4 years (range, 5 to 23 years). Clinical characteristics were similar between treatment sites. US patients reported better scores for physical ( P = .030), emotional ( P = .027), and school functioning ( P < .001). Chilean patients reported poorer scores for worry ( P < .001) and nausea ( P = .007). Patient and parent nausea scores were similar between patients treated in the United States and Chile by the end of therapy. Differences in symptom distress were not observed between the countries. Neither HRQOL measures nor treatment site were associated with EFS or OS.

Conclusion

Although significant differences in HRQOL were observed between countries, outcomes were similar, and HRQOL measures were not associated with prognosis.
ФАКТОРЫ УСИЛЕНИЯ ТЕРРОРИСТИЧЕСКОЙ АКТИВНОСТИ ГРУППИРОВКИ «ИСЛАМСКОЕ ГОСУДАРСТВО» НА ТЕРРИТОРИИ ЕВРОПЕЙСКОГО СОЮЗА
Authors: Lobanov Nikita Aleksandrovich
Published: March 2017

Начало XXI века ознаменовало собой усиление процессов глобализации и интеграции во всем мире. Это привело к тому, что международное сообщество, в особенности европейские государства, столкнулось с рядом новых угроз распространения исламистского терроризма, наиболее актуальной из которых является деятельность группировки «Исламское государство» (ИГ). В этом контексте важно определить причины интенсивного роста активности «ИГ» и его влияния на территории Европы.В статье проводится анализ факторов, способствующих распространению терроризма, а также приводится ряд рекомендаций, выполнение которых, по мнению автора, могут привести к снижению уровня террористической угрозы.Цель исследования – выявить факторы усиления влияния организации «Исламское государство» и увеличения числа террористических атак в европейских государствах.Автор приходит к выводу, что проблема «ИГ» представляет собой комплексную угрозу, для предотвращения которой необходим ряд усилий как внутри европейского континента, так и на территории Ближнего Востока, требующих системного подхода и высокого уровня консолидации и координации международного сообщества.
СОЦИАЛЬНО-ЭКОНОМИЧЕСКОЕ РАЗВИТИЕ ТЕРРИТОРИИ НА ОСНОВЕ ГОСУДАРСТВЕННО-ЧАСТНОГО ПАРТНЕРСТВА. ЧАСТЬ 1
Authors: Zakharov Sergey Viktorovich
Published: March 2017

Раскрыты методические подходы к описанию инструментов государственно-частного партнерства (ГЧП). Проанализированы противоречия, проблемы действенности институциональных средств регулирования эффективности функционирования разных форм ГЧП в российской экономике. Выделены некоторые недостатки законодательной базы как важного институционального инструмента развития ГЧП и регулирования экономических отношений. Обоснована целесообразность расширенного применения корпоративной формы партнерства и коррекции институтов и механизмов правового регулирования взаимовыгодных партнерских отношений, в том числе с участием акционерных обществ. Предложено расширить классификацию форм ГЧП для поиска путей совершенствования правового поля функционирования ГЧП и на этой теоретико-методологической основе внести ряд изменений в соответствующие законодательные акты.Цель: на основе анализа и расширенного толкования сущности и содержания ГЧП расширить классификацию их форм и предложить новые институциональные средства регулирования процессов партнерского взаимодействия государственных структур с предприятиями и социально-экономического развития территории.Метод или методология проведения работы: методология институциональной экономики; методы классификации, анализа экономических отношений и противоречий развития разных форм ГЧП, синтеза решений; проектный и системный, комплексный подход.Результаты: расширена классификация форм ГЧП, а также толкование сущности и содержания партнерских отношений между государством и бизнесом; представлена матричная модель сравнительных характеристик разных форм ГЧП; обоснована необходимость развития институциональных средств регулирования социально-экономического развития территорий с опорой на разные формы ГЧП; разработаны рекомендации по совершенствованию законодательной базы, способствующие повышению эффективности ГЧП и ускорению социально-экономического развития территорий.Область применения результатов: представленные решения и рекомендации предназначены для использования органами законодательной и исполнительной власти для регулирования экономических отношений при активном применении разных форм ГЧП с целью ускорения социально-экономического развития территорий.
Calculating Principal Eigen-Functions of Non-Negative Integral Kernels: Particle Approximations and Applications
Authors: Whiteley Nick , Kantas Nikolas
Published: March 2017

Often in applications such as rare events estimation or optimal control it is required that one calculates the principal eigenfunction and eigenvalue of a nonnegative integral kernel. Except in the finite-dimensional case, usually neither the principal eigenfunction nor the eigenvalue can be computed exactly. In this paper, we develop numerical approximations for these quantities. We show how a generic interacting particle algorithm can be used to deliver numerical approximations of the eigenquantities and the associated so-called “twisted” Markov kernel as well as how these approximations are relevant to the aforementioned applications. In addition, we study a collection of random integral operators underlying the algorithm, address some of their mean and pathwise properties, and obtain error estimates. Finally, numerical examples are provided in the context of importance sampling for computing tail probabilities of Markov chains and computing value functions for a class of stochastic optimal control problems.
Allenaltica, a new genus of flea beetles from the Oriental Region (Coleoptera: Chrysomelidae: Galerucinae: Alticini)
Authors: Prathapan Kaniyarikkal D. , Ruan Yong-Ying , Konstantinov Alexander S.
Published: March 2017

A new genus of flea beetles (Allenaltica gen. nov.) with a new species, Allenaltica flavicornis, sp. nov. from the Philippine Islands (Mindanao) is described, illustrated and compared with related genera.
Short Communication: Selected medicinal plants in East and North Kalimantan (Indonesia) against Propionibacterium acnes
Authors: ARUNG ENOS TANGKE , PASEDAN WHICLIFFE FIERNALEONARDO , KUSUMA IRAWAN WIJAYA , HENDRA MEDI , SUPRIADI MERY BUDIARTI
Published: March 2017

Abstract. Arung ET, Pasedan WF, Kusuma IW, Hendra M, Supriadi MB. 2017. Short Communication: Selected medicinal plants in East and North Kalimantan (Indonesia) against Propionibacterium acnes. Biodiversitas 18: 321-325. Based on community based research on ethnomedicine local knowledge and medicinal plant in Indonesia by Medicinal Plant and Traditional Medicine Research and Development Center of Indonesian Ministry of Helath in 2012 and 2015, various data on medicinal plants including for cosmetic in all Indonesia region has been collected. There are 38 medicinal plants use for skin care/cosmetics. This study focused on some selected medicinal plants used by several Dayak ethnic groups in East and North Kalimantan, Indonesia for cosmetic, especially for anti-acne. Four plants were selected for evaluating its property on anti-acne, namely Crotalaria pallida, Lepisanthes amoena, Premna corymbosa, and Vitex pinnata by well diffusion and dilution methods. The zone inhibition (mm) against Propionibacterium acnes of these leaves extract on anti-acne at 1000 mg/mL was 9.33; 16.44; 13.78; 11.00 mm, respectively and chlorampenicol (positive control) was 29.44 mm at 500 mg/mL. These results were in line with traditional used by Dayak tribes in East and North Kalimantan, Indonesia.

Keywords: Anti acne, cosmetic, medicinal plants, traditional medicine
Relationship of soil physical and chemical properties with ecological species groups in Pinus taeda plantation in northern Iran
Authors: ADEL MOHAMMAD NAGHI , DARYAEI MEHRDAD GHODSKHAH , PASHAKI MOHADDESEH SEDIGHI , JALALI JAVAD , KUHESTANI JAVAD SADEGH , JIROUDNEZHAD ROGHAYEH
Published: March 2017

Abstract. Adel MN, Daryaei MG, Pashaki MS, JalaliJ, KuhestaniJS, Jiroudnezhad R. 2017. Relationship of soil physical and chemical properties with ecological species groups in Pinus taeda plantation in northern Iran. Biodiversitas 18: 422-426. The aim of this study was to investigate the relationship of physical and chemical properties of soils with ecological species groups in Pinus taeda plantation forests in Guilan province, Iran. For this purpose, a random systematic 100 m Ã— 200 m grid sampling plan was used to establish 75 sampling plots. In each plot, soil factors and percent cover of each herbaceous species were recorded. Sub-plots of 32 m2 were used for herbaceous species measurements. At each sampling plot, soil samples were collected in depth of 0-30cm. The result of TWINSPAN analysis revealed five dictinct groups. Multivariate analysis was performed through CANOCO 4.5 to explore the relationship between soil factors and plant community. Results showed that the most important soil factors in these communities were N, P, K, OC, Ca, Mg, TNV, pH, SP, soil texture (clay, sand, silt) and EC. The results indicated that the physical and chemical soil characteristics have a significant role in the growth and distribution of plant communities in the study area.

Keywords: Pinus taeda, plantation, soil properties, vegetation
Effects of habitat degradation and fragmentation on butterfly biodiversity in West Kotawaringin, Central Kalimantan, Indonesia
Authors: HARMONIS HARMONIS , SAUD OSHLIFIN RUCMANA
Published: March 2017

Harmonis, Saud OR. 2016. Effects of habitat degradation and fragmentation on butterfly biodiversity in West Kotawaringin, Central Kalimantan. Biodiversitasx 18: 500-506. The main purpose of this study was to examine the effects of degradation and fragmentation habitats to butterfly communities. To be specific, species diversity, taxonomy structure, main species in every study sites were observed to find out the effects and correlation of each parameters. Field study was carried out in 8 sites in Kotawaringin Barat, Central Kalimantan Province, Indonesia. The specimens were collected using aerial insect nets and baited traps in January-February 2016. From the result of the study, the total of 1085 individual in 130 species was successfully collected. Based on distribution analysis using Shannon-Wiener index, the diversity of butterfly was in the range of middle to high categories (Hâ€™ = 2.7-3.5). Of another parameter analysis, it showed that butterfly communities were affected by degradation habitat, while fragmentation habitat did not influence to the butterfly communities. Furthermore, the range of degradation level in the study sites did not correlate with the number of species and taxonomy structures, but the distribution of the special-group of main species showed in correlation. Lexias dirtea was only found in dense forests (site S-7), then Neptis hylas and Parantica agleoides appeared in shrub habitat (site S-5 and S-6). The finding indicated that green patches have valuable contribution to conserve the ecosystem as valuable germplasm for butterflies and also arthropods.
Assessing phytoplankton community structure in relation to hydrographic parameters and seasonal variation (Pre & Post Monsoon)
Authors: MIRZAEI M. REZA , SERAJI FERESHTEH , ERFANIFAR ELNAZ , RAD TEYMOUR AMIN , AMINIKHOEI ZAHRA , AZHANG BIZHAN
Published: March 2017

Mirzaei MR, Seraji F, Erfani E, Rad TA, Aminikhoei Z, Azhang B. 2017. Assessing phytoplankton community structure in relation to hydrographic parameters and seasonal variation (Pre & Post Monsoon). Biodiversitas 18: 507-513. The present study is conducted to assess hydrographical parameters, phytoplankton composition and the relationship between physicochemical parameters and phytoplankton assemblages along Chabahar coastal waters, South coast of Iran. Based on the collected samples from four stations, all the hydrographical parameters such as sea surface temperature, salinity, pH, DO and nitrate, inorganic phosphate, silicate, and phytoplankton assemblages were studied for five months (from April 2014 to August 2014). A total of 165 phytoplankton groups/taxa were observed in which the Dinophyceae formed the dominant group in all seasons. During the pre-monsoon season, Dinophyceae (56.5%) was the most abundant phytoplankton group followed by Bacillariophyceae (40.8%), Cyanophyceae (1.7 %) and Dictyochophyceae (0.8%). Meanwhile, in the post-monsoon season, Dinophyceae was dominant (49.5%), followed by Bacillariophyceae (46.7%), Cyanophyceae (1.8%), and Dictyochophyceae (1.8%). The highest phytoplankton density was in mid-May (19584953Â± 345182 cell per litter) and the lowest was in late July (163928Â± 1790 cells per liter). Salinity, nitrate, phosphate, silicate showed significant variation (p<0.05) among seasons while pH, seawater temperature, dissolve oxygen did not show significant differences in all stations over the study periods (p<0.05). Phytoplankton density correlated positively with water temperature and salinity. Results showed an increased concentration in phytoplankton density during Pre-monsoon season followed by Post-monsoon and monsoon season.
Short Communication: Assessment of genetic diversity in Lai (Durio kutejensis) local cultivars of Batuah (Indonesia) using ISSR marker
Authors: HANDAYANI FITRI , RAHAYU SRIWULAN PAMUJI
Published: March 2017

Handayani F, Rahayu SP. 2017. Assessment of genetic diversity in Lai (Durio kutejensis) local cultivars of Batuah (Indonesia) using ISSR marker. Biodiversitas 18: 525-529. Lai is an indigenous germplasm of Kalimantan which has potency to be developed as superior tropical fruit. Lai has attractive flesh color from yellow to reddish orange which represents the high content of carotene with smooth aroma or odorless fruit, and fruit storage period which longer than durian. Unfortunately, nowadays there is limited scientific information about its genetic diversity as important basic information for genetic conservation and breeding program. Batuah village in Kutai Kartanegara District is one of the center of origin and center of diversity of Lai in East Kalimantan, Indonesia which has many local cultivars with superior traits. The aim of this research was to study the genetic diversity of eight Lai local cultivars of Batuah village using molecular marker of ISSR. The total genomic DNA of eight Lai cultivars was isolated and was then used as template in the PCR amplification reaction using 10 ISSR primers. The result shows that similarity coefficient of eight Lai cultivars ranged between 0,34 and 0,58. Seven cultivars were grouped in the same cluster with 0,44 of similarity coefficient, while Lai Durian was separated in 0,34 of similarity coefficient. Genetically, the most similar existing cultivars are Lai Kuning and Lai Belimbing with the similarity coefficient of 0,58.
Review: A working checklist of the freshwater fish diversity for habitat management and conservation work in Sabah, Malaysia, North Borneo
Authors: KEAT-CHUAN NG CASEY , ABDULLAH FATIMAH , BIUN HELENA , IBRAHIM MOHAMMAD KHADAFI , MUSTAPHA SHUHADAH , SADE AHEMAD
Published: March 2017

Ng CKC, Abdullah F, Biun H, Ibrahim MK, Mustapha S, Sade A. 2017. Review: A working checklist of the freshwater fish diversity for habitat management and conservation work in Sabah, Malaysia, North Borneo. Biodiversitas 18: 560-574. Prioritization of freshwater habitat management and conservation is dependent on the availability of species baseline information at regional level. However, such information has not been updated since 2002 in Sabah. Thus the objective of this paper is to present the latest working checklist of freshwater ichthyofauna known so far in the state. A literature review of 68 studies was conducted focusing on the latest valid binomial nomenclature, locality and conservation status. A total of 166 valid species, namely 150 native species and 16 introduced species, were deduced from the literature. Native species comprised of 10 orders, 27 families and 75 genera while introduced species were from four orders, seven families and 14 genera. The review revealed 103 species (68.6% of native species) were yet to be assessed for the IUCN Red List and 11 species (7.3%) were identified as Data Deficient by IUCN. Some taxonomic discrepancies were also found and discussed. Many areas in Sabah remain poorly inventoried due to unequal sampling effort, biophysical and cultural challenges. The species list proposed herein is tentative at best and the number of species is expected to increase as more surveys are conducted in the near future.
A biophysical observation of Mahakam River around Tanjung Una of Kutai Kartanegara, Indonesia
Authors: SUYATNA IWAN , MISLAN MISLAN , RAHMAN ANDRY , WINATA ARY , WIJAYA YUNI IRAWATI
Published: March 2017

Suyatna, I, Mislan. A. Rahman A. Winta Wijaya YI. 2017. A biophysical observation of Mahakam River around Tanjung Una of Kutai Kartanegara, Indonesia. Biodiversitas 18: 623-632. The aim of this study is to dig up more information about the biophysical conditions of Mahakam River around Tanjung Una of Kutai Kartanegara, Indonesia including the fishery potential in these locations. The observations were conducted in two periods. Through field surveys, the sample of fish and shrimp were caught with pulled nets from many stations, while to know the water quality around the location of the observation, water sampling was conducted and then the sample was brought to a laboratory to be analyzed in order to find out its quality. On the scale of taxonomy and ecology, community structure of fish and shrimp from 21 species of fish consisted of 17 families, five orders, and one class. For the shrimp, it was only four identified species of the genus Macrobrachium family Palaemonidae and genus Metapenaeus family Penaeidae ordo Decapoda class Malacostraca. The distribution of the length and weight of fish and shrimp was found out to be small. The value of the diversity index between the fish and shrimp showed low to moderate with a value of D: 0.150 to 0.601; H': from 0.986 to 2.089, E: 0.268 to 0.621 and Margalef: 1,475-2,345 for the fish and a value of D: 0.325 to 0.688, H': from 0.615 to 1.205, E: 0.462 to 0.834 and Margalef: from 0.490 to 0.614 for the shrimp. The index indicated that there were species that tend to dominate other species. The species richness was low. Physical-chemical properties and heavy metal content in the Mahakam River around Tanjung Una were generally still below the quality standard. The observations concluded that the number of marine fish species was found two times higher than the river fish species, but not to the number of population.
Short Communication: Characteristic of Anodendron paniculatum (Apocynaceae) in Mount Nglanggeran, Yogyakarta, Indonesia
Authors: WIDODO WIDODO , LUTHFI MUHAMMAD JAâ€™FAR
Published: March 2017

Widodo, Luthfi MJ. 2017. Short Communication: Characteristic of Anodendron paniculatum (Apocynaceae) in Mount Nglanggeran, Yogyakarta, Indonesia. Biodiversitas 18: 645-651. Anodendron paniculatum was found in climbing route of Mount Nglanggeran, Yogyakarta at coordinates location of 7Â°50'29.6" S and 110Â°32'19.5" E, at an altitude of 480 masl. The identification of A. paniculatum was conducted based on Museum Nasional d'Histoire Naturelle (MNHN), Paris, France with collection number of herbarium of P00256390. Information about A. paniculatum in Indonesia was very rare, even almost non-existent. This study aimed to describe the morphological characteristics of A. paniculatum included the morphology of flower, flower bud, leaf and stem. The study was conducted through periodically visiting at the research location. The observation was conducted to flowering period, the structure of flower and fruit and other supporting data. The specimen of samples were collected for herbarium collection and observation in the laboratory. The observation in the laboratory was conducted on morphological characteristics of habitus, stem, leaf and flower. The data were compared with literature and existing herbarium collections. The results of the study showed that the specimen of A. paniculatum is a liana, inflorescence in leaf axil and the end of branching, the size of panicle is about 15 cm, consisted of small yellowish tubular flowers with each flower has a length of 1.3 cm.
Characterization of acidophilic bacteria related to Acidiphilium cryptum from a coal-mining-impacted river of South Brazil
Authors: Delabary Gabriela Scholante , Lima André Oliveira de Souza , Castro da Silva Marcus Adonai
Published: March 2017

Three acidophilic bacteria were isolated from water and sediment samples collected at a coal mining-impacted river, Rio Sangão, located in the city of Criciúma, Santa Catarina state, in south Brazil. These microorganisms were isolated in acid media and were phylogenetic related to the species Acidiphilium cryptum by its 16s rRNA gene sequences, although they differ from this species in the assimilation of some carbon sources. The optimum and the maximum pH for growth of all strains were nearly 3.0 and 5.0-6.0, respectively. Two of the strains were slightly more acidophilic, with the minimum pH for growth of 2.0. All strains also tolerate the four tested metals (Ni, Zn, Cu and Se) at variable concentrations, with LAMA 1486 being the most metal-resistant strain. These bacteria may belong to different ecotypes of A. cryptum, or even represent new species in the genus. Besides they bear characteristics that make them useful in the development of bioremediation process, for the treatment of sites contaminated with multiple toxic metals, including coal mining drainage
OCORRÊNCIA DO LEITE INSTÁVEL NÃO ÁCIDO (LINA) NA REGIÃO NORTE DO MATO GROSSO
Authors: Martins Souza Helem Priscilla , Baldasso Romero Natália , Bueno da Rosa Claudineli Cássia
Published: March 2017

Objetivou-se com este estudo, detectar a ocorrência do leite instável não ácido (LINA) na região norte do Mato Grosso, Brasil. Foram analisadas 486 amostras de leite durante os meses de novembro de 2012 a junho de 2013, provenientes de 180 produtores diferentes. Os resultados obtidos apresentaram uma incidência de 13,95% para o leite LINA, demonstrando que há uma baixa ocorrência, no período em que foram realizadas as coletas.
Expiration of the Deadline in Civil Transactions: Comparing Omani and Egyptian Civil Codes in the Light of Islamic Law
Authors: Jadalhaq Iyad Mohammad
Published: March 2017

This research deals with the case in which the creditor claim the loan after the expiration date. It seeks to compare between the Civil Transactions Code of Oman and the Egyptian Civil Code. The paper argues that the Civil Transactions Code of Oman is influenced by the Islamic legal thought; while the Egyptian is influenced more by the Latin legal thought. The Islamic influnce in Oman can be seen at the provision that allows the legal process after the expiration date. The creditor may bring his case to the court to sue the debtor. While the Latin influnce in Egypt can be found on the rule that does not allow the legal process after the expiration date. The creditor loses his right when he does not claim the debt during the agreed period.[Penelitian ini berkaitan dengan masa kedaluwarsa bagi kreditor untuk mengklaim kredit dari debitur. Hukum Perdata Oman yang dipengaruhi oleh hukum fikih menetapkan bahwa dalam kasus ini, gugatan tidak dapat diterima dan debitur diizinkan untuk menolak gugatan terhadap dirinya oleh kreditur ketika gugatan tersebut diajukan setelah berakhirnya jangka waktu klaim. Sementara itu, Hukum Perdata Mesir yang dipengaruhi pemikirn hukum Latin, mengambil prinsip pembatasan dan pengguguran kewajiban jika kreditur tidak menagih pinjamannya dalam jangka waktu tertentu. Berdasarkan data tersebut, jelas bahwa dua undang-undang ini berbeda dalam mengatur waktu kedaluwarsanya suatu kasus hukum. Hukum yang pertama memberikan hak kepada debitur untuk menuntut bahwa pengadilan tidak perlu menerima gugatan kasus ini karena telah kedaluwarsa. Sementara itu, hukum kedua memungkinkan debitur untuk mematuhi jatuhnya hak klaim karena berakhirnya waktu dan ini bertentangan dengan prinsip hukum Islam, yang mengatur tidak adanya hak yang gugur tanpa peduli berapa lama waktunya, tetapi hanya membatasi kasus ini pada tidak perlunya menerima gugatan hak yang pemilik klaim dalam jangka waktu yang lama. Penelitian ini menyimpulkan bahwa sistem yang berasal dari hukum Islam lebih baik dari sistem yang berasal dari yurisprudensi Latin dan bahwa legislator pemerintah Oman tidak mengambil semua aturan dari para ahli hukum Islam.]
Resumos do XII Congresso Mundial de Farmacêuticos de Língua Portuguesa; V Simpósio de Plantas Medicinais e Fitoterápicos no Sistema Público de Saúde; Congresso Internacional de Fitoterapia; I Congresso Brasileiro de Farmácia Estética e I Simpósio Farmacêutico de Nutracêuticos
Authors: JOÃO Walter Da Silva Jorge , De SANTI Valmir
Published: March 2017

O Conselho Federal de Farmácia (CFF), a Associação de Farmacêuticos dos Países de Língua Portuguesa (AFPLP) e a Fundação Brasileira de Ciências Farmacêuticas (FBCF) têm a satisfação de apresentar a você, leitor, os anais do XII Congresso Mundial de Farmacêuticos de Língua Portuguesa.
A coherent modeling procedure to describe cell activation in biological systems
Authors: Scianna Marco , Colombi Annachiara
Published: March 2017

Biological systems are typically formed by different cell phenotypes, characterized by specific biological properties and behaviors. In particular, cells are able to undergo phenotypic transitions (i.e., activation or differentiation) upon internal or external stimuli. In order to take these phenomena into account, we here propose a modelling framework in which cell ensembles can be described collectively (i.e., through a distributed mass density) or individually (i.e., as a group of pointwise/concentrated particles) according to their biological determinants. A set of suitable rules involving the introduction of a cell shape function then defines a coherent procedure to model cell activation mechanisms, which imply a switch between the two mathematical representations. The theoretical environment describing cell transition is then enriched by including cell migratory dynamics and duplication/apoptotic processes, as well as the kinetics of selected diffusing chemicals inuencing the system evolution. Remarkably, our approach provides consistency of the same modeling framework across all types of cell representation, as it is suitable to cope with the often ambiguous translation of individual cell arguments (i.e., cell dimensions and interaction radii) into collective cell descriptions. Biologically relevant numerical realizations are also presented: in particular, they deal with phenotypic transitions within cell colonies and with the growth of a tumor spheroid. These phenomena constitute biological systems particularly suitable to assess the advantages of the proposed model and to analyze the role on cell dynamics both of relevant parameters and of the specific form given to the cell shape function.
Willing (White) Workers on Organic Farms? Reflections on Volunteer Farm Labor and the Politics of Precarity
Authors: Guthman Julie
Published: March 2017

Many young, university-educated adults these days go to work on organic farms as volunteers and interns, despite that this work is extremely demanding, painful, and has been historically demeaning. Through interviews and discussions with students, I have learned that many who participate in these ventures do so to travel, gain experience, and support organic farms yet rarely consider the impact of their voluntary labor on waged labor. I suggest that their interest in DIY experimentation more generally reflects different relationships to work than their middle-class parents enjoyed, as middle-class jobs become less desirable and attainable. I then juxtapose their chosen precarity with the situation of migrant farmworkers who are valued for their labor but do not receive biopolitical recognition. I conclude this research-inspired thought piece by positing that young adults who volunteer on farms and engage in other acts of self-provisioning may indeed be engaged in a politics of work reconfiguration but not one of solidarity.
Singapore Hawker Centers: Origins, Identity, Authenticity, and Distinction
Authors: Tam Andrew
Published: March 2017

Foodways in Singapore embody the anxieties of the island-state—namely heritage, race, identity, and authenticity. Hawking in Singapore was initially seen as a nuisance that had to be tolerated and later regulated by both the colonial administration and newly independent government. The relocation of hawkers to centralized food centers marked the imposition of order and hygiene onto a squalid industry. Street peddlers, once an administrative problem, were refashioned into a potent symbol of Singapore's heritage. Hawker food has also been used as a trope of multiculturalism to unite a racially diverse people. The influx of foreign workers from the mid-1980s presented new tensions that shed light on the cultural power of food to articulate inclusion and exclusion. Markers of authenticity, namely historical traditions and artisanal expertise, map haphazardly onto the realities of actual foodways. Finally, a breed of connoisseurs, who grew up in a cosmopolitan nation-state, was birthed in the 1990s. Embracing the low culture of hawker food, local foodies impute new cultural meanings to hawker food that embody the tension between distinction and democracy.
Use of Traumatic Brain Injury Prediction Rules With Clinical Decision Support
Authors: Dayan Peter S. , Ballard Dustin W. , Tham Eric , Hoffman Jeff M. , Swietlik Marguerite , Deakyne Sara J. , Alessandrini Evaline A. , Tzimenatos Leah , Bajaj Lalit , Vinson David R. , Mark Dustin G. , Offerman Steve R. , Chettipally Uli K. , Paterno Marilyn D. , Schaeffer Molly H. , Wang Jun , Casper T. Charles , Goldberg Howard S. , Grundmeier Robert W. , Kuppermann Nathan ,   for the Pediatric Emergency Care Applied Research Network (PECARN),   Clinical Research on Emergency Services and Treatment (CREST) Network,   and Partners Healthcare; Traumatic Brain Injury-Knowledge Translation Study Group
Published: March 2017

OBJECTIVES:

We determined whether implementing the Pediatric Emergency Care Applied Research Network (PECARN) traumatic brain injury (TBI) prediction rules and providing risks of clinically important TBIs (ciTBIs) with computerized clinical decision support (CDS) reduces computed tomography (CT) use for children with minor head trauma.

METHODS:

Nonrandomized trial with concurrent controls at 5 pediatric emergency departments (PEDs) and 8 general EDs (GEDs) between November 2011 and June 2014. Patients were <18 years old with minor blunt head trauma. Intervention sites received CDS with CT recommendations and risks of ciTBI, both for patients at very low risk of ciTBI (no Pediatric Emergency Care Applied Research Network rule factors) and those not at very low risk. The primary outcome was the rate of CT, analyzed by site, controlling for time trend.

RESULTS:

We analyzed 16 635 intervention and 2394 control patients. Adjusted for time trends, CT rates decreased significantly (P < .05) but modestly (2.3%–3.7%) at 2 of 4 intervention PEDs for children at very low risk. The other 2 PEDs had small (0.8%–1.5%) nonsignificant decreases. CT rates did not decrease consistently at the intervention GEDs, with low baseline CT rates (2.1%–4.0%) in those at very low risk. The control PED had little change in CT use in similar children (from 1.6% to 2.9%); the control GED showed a decrease in the CT rate (from 7.1% to 2.6%). For all children with minor head trauma, intervention sites had small decreases in CT rates (1.7%–6.2%).

CONCLUSIONS:

The implementation of TBI prediction rules and provision of risks of ciTBIs by using CDS was associated with modest, safe, but variable decreases in CT use. However, some secular trends were also noted.
Breve historia de la taxonomía del cuerpo y del pecado en el arte costarricense
Authors: Vargas Alvarado Sussy
Published: March 2017

A partir de una taxonomía del arte, se propone una investigación sobre el tema del cuerpo, el desnudo, el deseo y cómo estos han sido sistemáticamente censurados en los espacios expositivos costarricenses por su relación con el pudor, lo inadecuado y el pecado. A pesar de la censura, algunos artistas costarricenses han trabajado el tema del cuerpo desde diferentes perspectivas y visiones, con discursos alternativos que intentan abordar lo erótico y el deseo como una parte normal de la vida del ser humano. La presente investigación formula un inventario resumido desde las culturas precolombinas hasta las últimas expresiones artísticas contemporáneas, con el afán de estudiar los diferentes contextos en donde la censura y la prohibición han tomado lugar en el arte costarricense.
Lo que se bailó en Costa Rica. Actividad dancística ejecutada en los teatros capitalinos de Costa Rica durante el año 2015
Authors: Ávila Aguilar Marta
Published: March 2017

Este texto pretende, como resumen, dar una idea de cuál fue la principal actividad dancística de creadores nacionales y extranjeros que se ejecutó en los teatros capitalinos de Costa Rica durante el 2015.
Speaking Softly and Carrying a Big Stick in Edwin S. Porter’s The Teddy Bears (1907)
Authors: Quirós Oscar E.
Published: March 2017

La mayoría de los trabajos analíticos sobre Edwin S. Porter se centran en torno a la importancia histórica de si es o no Porter el primero en lograr la edición paralela. Sin embargo, algunas de sus obras presentan una interpretación crítica de la realidad económica y política de los Estados Unidos. El caso más relevante es el de The Teddy Bears (1907) donde, a través de la combinación de una fábula popular y la imagen del presidente de Roosevelt, Porter crea una parodia política no solo de Roosevelt, sino de las aventuras de los Estados Unidos contra España, Cuba , Panamá y Puerto Rico durante el periodo 1898-1904. Como cámara para la compañía Edison, Porter vio la guerra en persona y podía tener algunas ideas que no fue capaz de comunicarlas en sus actualités o “documentales” de la guerra; sin embargo, la evidencia apunta a que él trató de hacerlo en su películas de ficción. De acuerdo con lo antes mencionado, el presente artículo relaciona la invasión de Cuba, Puerto Rico y Panamá por parte de los Estados Unidos con los eventos presentados en la pantalla por el “doble” del presidente Teddy Roosevelt y los tres osos a quienes matan, les roban y encadenan en esta obra corta de 1907. La correlación de eventos entre las intervenciones extranjeras de Theodore Roosevelt y los del cazador en The Teddy Bears (1907) son tan paralelas que es muy probable que fue intencionalmente planificado por Porter, dejando poco espacio para una mera coincidencia.
El dispositivo del fantasma de Pepper: la intermedialidad y el efecto de presencia
Authors: Rojas Amador Paula
Published: March 2017

Este articulo tiene como objetivo el análisis de una de las técnicas de ilusión óptica más populares en el siglo XIX, conocida con el nombre de Pepper’s Ghost o el fantasma de Pepper. Esta técnica es una de las precursoras en la utilización de la imagen virtual en la escena, motivando una discusión vigente en nuestros días, la relación entre la presencia virtual y la presencia “real” en el teatro. Para la comprensión de este dispositivo, nos referiremos a la técnica y los elementos que intervienen en su proceso, así como a los conceptos de intermedialidad y la noción de efecto de presencia.
Aniquilando fronteras: hacia nuevos órdenes humanos. Desplazamiento y estrategias de reemplazo en Orgánico y Realia (Bucarest-Beirut)
Authors: Lapadat Beatrice
Published: March 2017

A lo largo de este ensayo se analiza la problemática de los encuentros interculturales, en el contexto performativo/teatral, tal y como los generan el desplazamiento, la transgresión de fronteras y los conflictos armados. El ensayo examina las estrategias de reemplazo por medio de los intercambios culturales y las mutaciones de identidad empleadas en el espectáculo teatral Orgánico, dirigido por Andrei Majeri (Teatro Nacional de Bucarest, 2014), y en la performance Realia (Bucarest-Beirut), de 2012, dirigido por Farid Fairuz. La hipótesis que impulsó esta investigación postula que el desplazamiento puede establecer nuevos terrenos para la interacción humana, por un lado, y para expresiones escénicas innovadoras por el otro. Si Orgánico destaca, con trasfondos más bien oscuros, tanto la deshumanización que implica el tráfico de órganos y la posibilidad de redención, Realia (Bucarest-Beirut) utiliza la autoficción, las identidades múltiples y el humor con el fin de denunciar firmemente la futilidad de las fronteras. Lo que fomenta un vínculo artístico e intercultural tan fecundo entre Orgánico y Realia son la transgresión de límites –tanto físicos como ideológicos– y la empatía que se siente hacia el Otro, que está bajo amenaza. A partir de estos mecanismos escénicos se analiza el impacto que un conflicto social pueda tener sobre las interacciones humanas. El concepto de desplazamiento empleado a lo largo de esta investigación está discutido dentro del marco conceptual establecido por la biopolítica de Foucault y por la teoría de la desterritorialización de Deleuze y Guattari.
Le Camion (1977) de Marguerite Duras: palabra y filme
Authors: Guimaraes de Oliveira Luciene
Published: March 2017

En la película Le Camión (El camión, 1997), de Marguerite Duras, en lugar de ver un filme, vemos a laguionista, Duras, y al actor Gérard Depardieu, leer un guion. A través de ese proceso inconcluso de esoque habría sido un film, Duras propone al espectador imaginar una historia antes que verla en imágenes.En ese acto de lectura intermedial, el espectador asiste a un filme que reposa casi exclusivamenteen la palabra y en el que podemos constatar el cruce de elementos característicos del texto literario, dela imagen y de la escena. Este artículo propone explorar la paradoja que reside en este proyecto de obrainacabada, propio de la poética durasiana.
Foi Carmen Miranda de Antunes Filho y el gesto intercultural
Authors: Funchal Claudia
Published: March 2017

A partir del espectáculo Foi Carmen Miranda (Fue Carmen Miranda) del director brasileño Antunes Filho, este artículo busca una reflexión sobre la interculturalidad del discurso gestual. En esta puesta en escena de Antunes Filho, las culturas de Brasil y de Japón se mezclan, sin que por ello pierdan su identidad, constituyendo una gestualidad mestiza. Utilizando los conceptos de “intercultural” y “mestizaje”, según Gilles Verbunt y Liviu Dospinescu, discutimos cómo los elementos de dos culturas diferentes están presentes simultáneamente en la puesta en escena, poniendo en evidencia su oposición o complementariedad, como a la vez deja una brecha abierta para diferentes interpretaciones, según la referencia cultural del público. Asimismo, relacionamos personajes claves de la cultura brasileña y su gestualidad, con los conceptos de “tiempo del cuerpo” y “tiempo social” en la danza butoh, según Toshiharu Kasai y Kate Parsons (2003). Nuestra intención es demostrar que se trata de una puesta en escena intercultural legible desde al menos dos perspectivas, la del público japonés y la del brasileño.
El flaneo virtual a través de Google Street View como una práctica artística
Authors: Rojas Rocha Rodolfo
Published: March 2017

Este artículo propone una descripción de la ruta virtual como una práctica artística. Esta se explica por el flaneo digital, que se recrea a través de la pantalla del ordenador en tanto que imagen de la web, funcionando como espacio de manipulación de referentes geográficos y orientando el desarrollo puntual de una obra. Dentro de este análisis se identifican tres categorías de flâneur: premoderno, moderno y contemporáneo. Luego se delimitan los dos tipos de walkscapes virtuales seguidos de la manipulación de los referentes geográficos, con el fin de establecer estrategias de producción visual. El primer aspecto, considera el paseo virtual como experiencia de recolección de datos realizada por los agentes que capturan las imágenes urbanas, estudiando las operaciones itinerantes en el Google Street View. La segunda operación, (realizada por el usuario o flâneur final) es determinada por la recolección de esa información pertinente que ayuda a la elaboración proyectual de la obra plástica o visual en potencia, en el contexto del laboratorio. Se trata de ir coleccionando una serie de patrones, de territorios, paisajes modernos y calles aglomeradas, fotografiados en 360 grados, por medio de los cuales se dispone un conjunto de rutas urbanas concretas. Interesa, también, la manipulación de imágenes digitales en las que el andar sobre las fotos instaura un estado de simulacro gracias a la acción operativa sobre la imagen capturada. En fin, este paseo por Street View permite reconocer unos sistemas ópticos como abstracciones plásticas, que nacen de pantallas interactivas mediante el empleo de recursos de la web social.
El impacto del didactiquismo en el proceso educativo de la lengua y la literatura en la Educación Primaria: un reto de todos
Authors: González Araya María Nidia
Published: March 2017

Este artículo científico es producto de una investigación cualitativa cuyo propósito trascendental fue elaborar un diagnóstico para identificar las necesidades de educación continua en el área de la Didáctica de la lengua, en docentes de Educación Primaria de una Dirección Regional de Educación. En dicha investigación participaron diez directores, ciento treinta y dos docentes pertenecientes a veinticuatro escuelas de los diferentes los circuitos escolares, así como dos autoridades de una Dirección Regional de Educación. Como principales técnicas de recolección de datos, se utilizaron el cuestionario y la entrevista. Entre los resultados más importante se obtuvo que tanto las autoridades de la Dirección Regional como los directores de centros educativos y los docentes no han logrado construir una base teórica y conceptual acerca de la Didáctica de la lengua para fundamentar su intervención didáctica en la mediación pedagógica con los niños y las niñas de la Educación Primaria, razón por la cual resulta urgente abrir espacios de formación y actualización para ellos, a fin de que puedan brindar una respuesta más asertiva al proceso educativo de la Didáctica de la lengua y la literatura, desde el enfoque comunicativo propuesto por diversos autores y por el Ministerio de Educación Pública.
El método NIR combinado con el análisis quimiométrico PLS-da para determinar la adulteración del aceite de oliva con aceite de girasol
Authors: Bolaños Alfaro John Diego
Published: March 2017

Las cualidades nutricionales del aceite de oliva virgen y su alto precio en el mercado, lo convierten en un producto accesible para la adulteración; una mezcla con aceites de menor precio son difíciles de percibir en el producto embotellado, pero su calidad se perjudica. Este artículo reseña una regresión de mínimos cuadrados parciales, unida a un análisis discriminante (PLS-DA) como técnica de clasificación estadística. El modelo construido calculó la incógnita 1: 73.5 ± 6,5% aceite de oliva, la incógnita 2: 84,2±6,4% y la incógnita 3: 58,2 ± 6,5%. Al comparar los datos reales de las incógnitas, se evidencian valores confiables, dado que la incógnita 1 fue adulterada con un 30% de aceite de girasol, la incógnita 2 con 15% y la incógnita 3 con 40%. El porcentaje de error promedio de predicción propuesto es de un 2%; sin embargo, no se recomienda como técnica de cuantificación en porcentajes de adulteración menores al 7%, dado que la variabilidad de las muestras provoca solapamientos de clases. Se concluye que la técnica de espectroscopia infrarrojo cercano (NIR) permite clasificar y cuantificar adulteraciones de aceite con naturalezas de origen distintas, de una manera fácil y rápida, pero necesariamente sí se aplica un pretratamiento espectral unido al respectivo análisis y tratamiento estadístico de los datos.
Análisis sociocrítico de la construcción identitaria: el caso del libro Lo que se canta en Costa Rica
Authors: Carmona Ruiz Jorge Eduardo
Published: March 2017

En este artículo se presenta un análisis basado en los enfoques de la musicología sistemática según Lehnhoff (2005) yla sociocrítica (Amoretti, 1995; Carvajal, 2013) de Cros (1986a), sobre las relaciones interdiscursivas e intertextualesentre un grupo de canciones con letra de poetas nativos de San Ramón de Alajuela, Costa Rica. Se llega a la conclusiónde que su “visión de mundo” se basa en la imagen del “labriego sencillo”, creada a partir de la letra del Himno Nacional,y en la influencia que ejerció en los poetas su origen ramonense
BIO.ECONOMIC OPTIMAL LEVELS OF THE BALI STRAIT SARDINE FISHERY OPERATING IN A FLUCTUATING ENVIRONMENT
Authors: Purwanto Purwanto
Published: March 2017

There was an indication that fishing intensity was not the only factor affecting the abundance of Bali sardine stock.
Concluding commentary: Medical Education in Difficult Circumstances
Authors: McLean Michelle , Gibbs Trevor , McKimm Judy
Published: March 2017

This article was migrated. The article was marked as recommended. We live in difficult times. As three medical educators with many years of experience in medical education in different contexts and in a range of countries, we recognise that many educators and students face 'difficult circumstances'. Over the 18 months or so, including a theme at the 2016 AMEE Conference in Barcelona, we have collaborated with colleagues and students to identify some of our 'wicked' problems as well as possible solutions in medical and health professions' education. This Commentary summarises the contexts, difficulties and actual or potential solutions (e.g. low-resource settings, adverse weather events) described by collleagues who submitted articles to the January-March themed edition of MedEdPublish. In most of the submissions, we identified resourceful interventions and frameworks for tackling 'difficult circumstances'. Over the next few months, we will collate the information we have collected with the view to offering a range of frameworks and collaborative opportunities to support colleagues requiring assistance.
Soul, butterfly, mythological nymph: psyche in philosophy and neuroscience
Authors: Antonakou Elena I. , Triarhou Lazaros C.
Published: March 2017

ABSTRACT The term “psyche” and its derivatives – including “Psychology” and “Psychiatry” – are rooted in classical philosophy and in mythology. Over the centuries, psyche has been the subject of discourse and contemplation, and of fable; it has also come to signify, in entomology, the order of Lepidoptera. In the current surge of research on brain and mind, there is a gradual transition from the psyche (or the “soul”) to the specified descriptors defined by the fields of Behavioral, Cognitive and Integrative Neuroscience.