bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantum computing and financial risk management: A theoretical review and implications
Authors: Mayokun Daniel Adegbola  , Ayodeji Enoch Adegbola  , Prisca Amajuoyi  , Lucky Bamidele Benjamin  , Kudirat Bukola Adeusi
Published: June 2024

This review paper examines the potential implications of quantum computing for financial risk management. It explores the fundamental principles of quantum computing, including qubits, superposition, and entanglement. It discusses its advantages over classical computing for risk assessment and mitigation. The paper outlines traditional approaches to financial risk management. It explores how quantum algorithms, such as quantum Monte Carlo methods and quantum annealing, can enhance these strategies. Challenges and barriers to adopting quantum computing in the financial industry are identified, along with future research directions. Ultimately, the paper highlights the transformative potential of quantum computing for improving risk management in today's complex financial markets.
Keywords: Quantum Computing, Financial Risk Management, Qubits, Quantum Algorithms, Monte Carlo Simulations, Portfolio Optimisation.
The integration of artificial intelligence in cybersecurity measures for sustainable finance platforms: An analysis
Authors: Ezekiel Onyekachukwu Udeh  , Prisca Amajuoyi  , Kudirat Bukola Adeusi  , Anwulika Ogechukwu Scott
Published: June 2024

This study delves into the integration of Artificial Intelligence (AI) in cybersecurity measures within smart cities, aiming to uncover both the challenges and opportunities this fusion presents. With the burgeoning reliance on interconnected digital infrastructures and the vast data ecosystems within urban environments, smart cities are increasingly susceptible to sophisticated cyber threats. Through a systematic literature review and content analysis, this research identifies the unique cybersecurity vulnerabilities faced by smart cities and evaluates how AI technologies can fortify urban cybersecurity frameworks. The methodology encompasses a comprehensive review of recent scholarly articles, industry reports, and case studies to assess the role of AI in enhancing threat detection, response, and prevention mechanisms. Key findings reveal that AI-driven cybersecurity solutions significantly enhance the resilience of smart cities against cyber threats by providing advanced analytical capabilities and real-time threat intelligence. However, the study also highlights the critical need for robust ethical and privacy considerations in the deployment of AI technologies. Strategic recommendations are provided for policymakers, urban planners, and technology leaders, emphasizing the importance of integrating secure AI-enabled infrastructure and fostering public-private partnerships. The study concludes with suggestions for future research directions, focusing on the ethical implications of AI in cybersecurity and the development of scalable AI solutions for diverse urban contexts.
Keywords: Artificial Intelligence, Cybersecurity, Smart Cities, Urban Resilience.
Harnessing data analytics: A new frontier in predicting and preventing non-communicable diseases in the US and Africa
Authors: Chukwudi Cosmos Maha  , Tolulope Olagoke Kolawole  , Samira Abdul
Published: June 2024

Non-communicable diseases (NCDs), including heart disease, diabetes, and cancer, represent a significant global health challenge, particularly in the US and Africa. With rising prevalence rates, these chronic conditions strain healthcare systems and economies. This Review explores how data analytics can revolutionize the prediction and prevention of NCDs in these regions, highlighting its potential to transform public health strategies. Data analytics encompasses a range of techniques, including statistical analysis, machine learning, and predictive modeling, to extract meaningful insights from vast datasets. In the US, where healthcare systems generate massive amounts of electronic health records (EHRs), data analytics enables the identification of risk factors, early detection of diseases, and personalized intervention strategies. For instance, predictive algorithms can analyze patient data to identify individuals at high risk for developing NCDs, allowing for timely and targeted preventive measures. In Africa, the integration of data analytics faces unique challenges and opportunities. While the continent has less extensive healthcare data infrastructure compared to the US, mobile health (mHealth) technologies offer a promising solution. By leveraging mobile devices, health data can be collected, analyzed, and utilized to monitor and manage NCDs in remote and underserved communities. Data analytics can also aid in understanding the socio-economic and environmental determinants of NCDs in Africa, providing a comprehensive view of the factors contributing to disease prevalence. Comparatively, both regions can benefit from shared knowledge and collaborative efforts in harnessing data analytics for NCD prevention. Cross-continental partnerships can facilitate the exchange of expertise, technology, and best practices, fostering innovation and improving health outcomes. Furthermore, ethical considerations and data privacy must be prioritized to ensure responsible and equitable use of health data. In conclusion, data analytics holds immense potential to predict and prevent NCDs in the US and Africa. By leveraging advanced analytical techniques, healthcare systems can move towards more proactive and personalized approaches to disease management. Embracing this new frontier requires investment in data infrastructure, capacity building, and cross-regional collaboration, ultimately paving the way for healthier populations and sustainable healthcare systems.
Keywords: Harnessing, Data Analytics, Frontier, Predicting Non- Communicable Diseases, Preventing.
Leveraging machine learning to enhance instrumentation accuracy in oil and gas extraction
Authors: Dazok Donald Jambol  , Ayemere Ukato  , Chinwe Ozowe  , Olusile Akinyele Babayeju
Published: June 2024

The review explores the application of machine learning (ML) to improve the accuracy of instrumentation in the oil and gas industry. The paper discusses the challenges faced in instrumentation accuracy and how ML can be utilized to address these challenges. It highlights the benefits of using ML, such as improved data accuracy, reduced maintenance costs, and enhanced operational efficiency. The review also covers the future prospects of ML in the oil and gas industry and concludes with a call to action for companies to adopt ML technologies to improve instrumentation accuracy. In the oil and gas industry, accurate instrumentation is crucial for ensuring safe and efficient operations. However, maintaining high levels of accuracy can be challenging due to factors such as environmental conditions, equipment aging, and human error. Machine learning (ML) offers a promising solution to enhance instrumentation accuracy by leveraging data-driven insights to improve monitoring and control systems. ML algorithms can analyze large volumes of data from various sensors and equipment to identify patterns and anomalies that may indicate potential issues. By continuously learning from new data, ML models can adapt to changing conditions and improve their accuracy over time. This proactive approach can help prevent equipment failures, minimize downtime, and optimize production processes. Furthermore, ML can also help reduce maintenance costs by enabling predictive maintenance strategies. By analyzing equipment performance data, ML models can predict when maintenance is likely to be needed, allowing operators to schedule maintenance activities proactively. This can help avoid costly unplanned downtime and reduce the need for unnecessary maintenance checks. Overall, leveraging ML to enhance instrumentation accuracy in oil and gas extraction offers significant benefits. It can improve operational efficiency, reduce costs, and enhance safety. As ML technologies continue to advance, the future prospects for enhancing instrumentation accuracy in the oil and gas industry look promising. Companies that embrace ML technologies stand to gain a competitive edge in the industry by improving their operational performance and reducing risks.
Keywords: Leveraging, ML, Enhance, Instrumentation Accuracy, Oil and Gas Extraction.
Environmental Disclosure Practices in India (A Comparative Study Of Tata Consultancy Services And Wipro Ltd.)
Authors: Sharma Prerna , Banerji Priyanka
Published: June 2024

This study has been undertaken to compare and evaluate the environmental reporting practices followed by the top two Information Technology service companies working in India. Tata Consultancy Services and WIPRO are examined, which are among the top five companies in the global A list in the Global Reporting Initiative (GRI Index). The objective of this research paper is to lay emphasis on environmental disclosures at the corporate level and understand the importance of green accounting. In this study, five successive sustainability reports of both companies are examined on the various parameters such as water conservation, waste management, Greenhouse gas (GHG) emissions, energy conservation, etc., and comparative analysis is performed. Corporates are voluntarily disclosing environment-related information in their annual reports. However, there is no set standard practice to disclose such information, due to which wide disparities could be seen in these reports.
Technology-Based English Language Instruction in Pakistan: An Empirical Review
Authors: Razzaq Nasir
Published: June 2024

English language teaching has advanced greatly because of the incorporation of modern technology. Electronic teaching systems have positive effects on student engagement and English language acquisition. The vast majority of modern English language teachers make use of some form of technology help in the classroom. The present study addresses various aspects of technology used in English education in Pakistan by building creative curriculum that utilizes contemporary scientific and technical advancements, educating instructors with technological skills to ensure effective and quality topic delivery, and creating student-teacher platforms that optimize positive language learning results. This research combed the appropriate literature for definitions of technology in both contemporary and historical contexts, then connected these definitions with effective pedagogical practices. In light of this, the researcher presents a definition of the study's central topic, an explanation of the study's aims and hypotheses, and the study's results. The paper concludes with a list of suggestions for furthering the implementation of modern technologies in academic settings.
Copy Right Act: Developments and Issues in Indian Perspective
Authors: Rao Muppidi Srinivasa
Published: June 2024

“Creative India and innovative India “is the slogan of Indian policy of Intellectual Property Right. Copy right is a provision to author given by the law of authority of his or her work such as literature , music, software programming , artistic works, sound recording and etc. Implementation of Information and communication technology into traditional libraries, many changes may occur in library services .such as housekeeping services, charging-discharging systems, circulation systems are automated in the libraries. 1994 amendment is responsible for communication broadcasting new technology computer applications into the communication. 1999 amendment responsible made the Copyright Act fully compatible with the Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement .This paper supposed to give an importance Copyright All the librarians have to know the copyright laws which are enacted in national and international acts to proper maintenance of the library. To educate, the users is importance of Indian copyright act. To promote , copyright laws in Indian library system.
Using Novels as Pedagogical Tools for Teaching Cross-Cultural Competence to English Language Students: Focus on Speech Acts
Authors: David Maya , Ameer Ali
Published: June 2024

This study discusses the importance of developing cross-cultural competence among students of English language. It is argued that novels written in different contexts can be used as pedagogical material to teach students how the use of speech acts vary from one cultural context to another cultural context. Understanding this difference can help encourage mutual understanding and mutual respect between interlocutors coming from different cultural contexts. Data collected through purposive sampling from novels written in a range of contexts were qualitatively analysed to demonstrate how cross-cultural competence can be developed among students of English using culturally appropriate literary dialogues as pedagogical tools. It is suggested that dialogue-based language input of speech acts taken from novels can help students of English understand the importance of socio-cultural context in which speech acts are embedded.
Effects of Domestic Responsibilities on Career Growth among Women Journalists in Kenya
Authors: Issack Farhiya Ibrahim , Ndung’u Kahura , Oloo Ong’ong’a Daniel
Published: June 2024

The purpose of this study is to investigate effects of domestic responsibilities career growth of women journalists in Kenya. Specifically, the study sought to examine extent in which domestic duties affect women journalists’ thoughts on their career progression and explore how women journalists cope with inequalities in the media organizations in Kenya. The study used feminist theories to explain the study under study. Online questionnaire was administered to 358 journalists whose details were extracted from Media Council of Kenya Accreditation database. Descriptive research design was adopted by this study. Quantitative and qualitative approaches were used to analyze data from questionnaire and in-depth interview on women journalists. The study found that the working environment for women journalists presents unique issues attributed to domestic duties. The study found that 79% of the study participants strongly believed that newsrooms working environment favors male journalists as they can easily report to work after childbirth, balance family and work while climbing the corporate ladder. In conclusion, women journalists are likely to perform dismally due to domestic responsibilities. There is need for future studies to undertake a qualitative study to examine individual women journalists with young children to see how they are coping with them situation and how this affects their career progression. Women journalists requires space to progress in their career and to operate in an environment that is free from obstacles that hinders them from moving upwards in their organizations. This study is important because it investigates the domestic factors and their effects on women journalists’’ progression in Kenyan media industry.
RISCOS DA AUTOMEDICAÇÃO E A IMPORTÂNCIA DA VENDA CONTROLADA DE MEDICAMENTOS
Authors: Calado Guilherme de Araújo , Silva Marília Vital da , Lima Cristiane Gomes
Published: June 2024

A automedicação, embora arraigada na cultura, contribui para um alto número de mortes no país, evidenciando a necessidade de conscientização sobre os riscos envolvidos. Neste contexto, o trabalho ressalta que os Medicamentos Isentos de Prescrição (MIPs) são amplamente utilizados devido a fatores como acesso facilitado, custo acessível e influência midiática, o estudo alerta para os potenciais efeitos adversos decorrentes do uso inadequado. Destacando também o papel fundamental do farmacêutico na promoção do uso racional de medicamentos, enfatizando a importância da atenção farmacêutica para orientar os pacientes e otimizar a farmacoterapia. Em suma, o estudo destaca a necessidade de orientação adequada à população sobre os perigos da automedicação a longo prazo e a importância de receber os medicamentos adequados às necessidades individuais.
APLICAÇÃO DOS INIBIDORES DE SGLT2 NA INSUFICIÊNCIA CARDÍACA
Authors: Lima Pedro Paulo Gusmão de , Costa Fabiany Almada , Fonseca Luísa Alves de Sousa , Aguiar Alberto Ardisson de , Lima Gabriela Gusmão de
Published: June 2024

As doenças cardiovasculares representam uma importante parcela de agravos em saúde. Nesse aspecto, destaca-se a insuficiência cardíaca (IC) como prevalente e preocupante patologia, tendo em vista sua capacidade de reduzir a qualidade de vida e aumentar a morbimortalidade. Como possíveis opções terapêuticas, incluem-se inibidores da enzima conversora de angiotensina, bloqueadores do receptor de angiotensinogênio, betabloqueadores, diuréticos, antiarrítmicos, entre outros. Nesse sentido, estudos têm sido desenvolvidos para inclusão dos inibidores do SGLT2 na terapia da IC. As principais evidências destacam o enorme benefício desses medicamentos, incluindo melhora da função cardíaca, redução do número de hospitalizações e do número de mortalidade, valendo-se, portanto, a aplicação global dessa classe no tratamento da IC, objetivando melhores desfechos clínicos.
O PAPEL DO FLÚOR NO CONTROLE, NA PREVENÇÃO E NO ESTÁGIO INICIAL DA LESÃO CARIOSA: REVISÃO DE LITERATURA
Authors: Moura Maria Sabrina Borges , Rezende Marcus Ricardo Silva , Almeida Mylena da Silva , Costa Margarida Maria Silva Sá Mendes da , Gonçalves Natacha Kalu dos Santos Bernardes , Costa Juliana Noleto
Published: June 2024

A  cárie dentária continua sendo prevalente na cavidade oral. Sua progressão é multifatorial, resultante da combinação de vários elementos bactérias cariogênicas, ingestão de alimentos, higiene oral inadequada e fatores salivares. A odontologia vem caminhando para uma detecção, diagnóstico e escolha de tratamento mais conservador, com a utilização do fluoreto para meios preventivos e terapêuticos nas lesões iniciais, proporcionando uma paralisação destas. O objetivo dessa revisão de literatura é destacar a importância do flúor na prevenção e controle das lesões de cárie iniciais, promovendo a remineralização rápida e eficaz da estrutura dentária. A busca de estudos foi realizada a partir de um banco de dados científicos, “Google Acadêmico” , “Scielo” (Scientific Eletronic Library Online) e ‘‘Pubmed’’ utilizando uma associação de descritores no DeCS/MeSH. Os critérios de inclusão foram: artigos publicados de estudos clínicos e revisão de literatura em inglês e português publicados entre 2016-2024, e salvo os mais antigos que tivessem grande revelância no assunto, disponibilizados online. Nesse sentindo, destaca-se nessa pesquisa a importância do uso do flúor como forma eficaz no controle da doença cárie dentária e demonstrando uma efetividade na prevenção e no tratamento frente as lesões cariosas em fases iniciais.
PRÁTICAS RESTAURATIVAS NA PERSPECTIVA DA INCLUSÃO
Authors: Panta Bárbara Gai Zanini , Pavão Sílvia Maria de Oliveira
Published: June 2024

O presente artigo tem por objetivo apresentar uma reflexão acerca das Práticas Restaurativas e Inclusão Escolar. Investiga-se, neste caso, a relação entre estas práticas e os processos de inclusão em uma escola de ensino fundamental. A pesquisa, de natureza básica e abordagem qualitativa, busca trazer, de modo explicativo, uma análise dos diários de campo das atividades restaurativas realizadas nesta escola. Os resultados desta análise mostraram que os estudantes, de maneira geral, mudaram seu olhar a respeito das diferenças, ao mesmo tempo em que os estudantes público-alvo da educação especial se mostraram mais confiantes em sala de aula regular. Percebeu-se o aumento da autoestima e principalmente, uma melhora significativa nas interações entre todos os estudantes. Conclui-se, com este estudo, que a atividade de Práticas Restaurativas aliadas ao AEE contribui para o processo de inclusão, auxiliando principalmente na promoção de acessibilidade atitudinal e rompendo estereótipos.
ORÇAMENTO PARTICIPATIVO: UMA ANÁLISE DA PERCEPÇÃO DOS MUNÍCIPES DE IGUATU, ICÓ E ORÓS
Authors: Pedro Naiane Vieira , Chagas Milton Jarbas Rodrigues
Published: June 2024

O presente estudo teve como objetivo analisar a percepção da população sobre o orçamento participativo nos municípios de Iguatu, Icó e Orós, explorando a eficácia e os desafios desse mecanismo de participação cidadã. Utilizando questionários, coletamos dados que revelaram um conhecimento significativo sobre o orçamento participativo entre os moradores, mas também destacaram áreas de melhoria, especialmente em termos de divulgação e engajamento comunitário. Este estudo contribui para a compreensão do orçamento participativo, destacando a importância de estratégias que promovam maior conscientização, inclusão e comunicação contínua com a comunidade.
Les évolutions des liens sociaux autour des nouvelles pratiques alimentaires
Authors: Séré de Lanauze Gilles
Published: June 2024

Manger est-il toujours l’acte social autour du partage d’un repas ? Peut-on encore manger ensemble ? Cet ouvrage apporte un éclairage sur les multiples évolutions des liens sociaux autour de l’alimentation en regard des changements observés dans notre société.Rappelant les bienfaits, en particulier nutritionnels, mais aussi les difficultés de manger ensemble, Les évolutions des liens sociaux autour des nouvelles pratiques alimentaires montre comment les régimes alimentaires tendent à s’individualiser et à se fondre dans d’autres périmètres sociaux, sous l’influence de nouvelles préoccupations et au sein de nouvelles communautés, souvent différentes du traditionnel noyau familial.Ces jeux d’influences sociales, leurs évolutions et leurs conséquences sont étudiés sous plusieurs angles et dans différents cadres d’expression : suivi de régimes diététiques ou thérapeutiques, végétarisme, ou encore pratiques alimentaires liées à un culte religieux. Les implications en termes d’offre ou de distribution ainsi que les notions de proximité et de terroir sont également explorées. Enfin, la question est posée des bouleversements que la crise de la Covid-19 aura introduits dans nos façons de manger ensemble.
Modèles et méthodes pour l’évolution biologique
Authors: Didier Gilles , Guindon Stéphane
Published: June 2024

À l’origine de la diversité du vivant, l’évolution biologique est le phénomène par lequel les espèces naissent, se transforment ou disparaissent au cours du temps. Son étude fait intervenir des méthodes d’analyse sophistiquées qui reposent à la fois sur la modélisation mathématique des processus biologiques qui interviennent et sur la conception d’algorithmes efficaces pour ajuster ces modèles aux données génétiques et morphologiques.Modèles et méthodes pour l’évolution biologique expose les principales méthodes utilisées pour étudier l’évolution et offre un large panorama illustrant la variété des approches formelles mises en oeuvre notamment dans l’optimisation combinatoire, les modèles stochastiques, l’inférence statistique, l’échantillonnage par Monte-Carlo.Certaines des applications marquantes de ces méthodes y sont détaillées. Elles concernent, par exemple, l’étude d’événements migratoires des anciennes populations humaines ou la progression des épidémies.
For Gülden
Authors: Elafros Athena
Published: June 2024

Panel Honouring the late Dr. Gülden Özcan, University of Lethbridge, Women Scholars’ Speaker Series
Examination of Outliers as Mediator Variables Between Resiliency and Academic Performance
Authors: Angeles Melvin D.
Published: June 2024

In the higher educational setting measures have been initiated to aid college students in overcoming various setbacks and hindrances that can limit them from academically performing well. Extant literature pointed out the significant role of resilience in addressing the concerns of the college students, such as drop-out rates, academic failure, high perceived stress, low school engagement, and poor sense of psychological wellness. Different variables emerge after data analysis were helpful in understanding the deviant points or outliers/distinct. With this, the present study aims to determine the outliers’ profile, resiliency component scores, General Weighted Average (GWA) and outliers’ detection criteria and; examining outliers using Stem-and-Leaf plots and Scattered Diagram and explored outliers’ distinct characteristics or emerging themes. The present study assessed 560 students and yielded 15 data outliers/distinct that appeared in Stem-and-Leaf plots and Scattered Diagrams. Eleven (11) outliers/distinct were identified as mild outliers/distinct, and four were extreme outliers/distinct after the observation was conducted.  It is evident that four (4) extreme scores were described with very low academic performance, but the resiliency score fell into average to high resiliency values. The present study is vital in understanding resiliency and academic performance in the present context thus recommends the exploration of mediator variables namely students' innate intelligence and resiliency behaviors are product of extreme experiences that may affect the relationship between resiliency and academic performance.
Graduates Without Jobs: Understanding the Situation of Unemployed Kachin Youth in Myanmar
Authors: Ps. Hpung Awng
Published: June 2024

Unemployment among college graduates has become a global issue that puts young people in a disadvantaged position. Employing a collective case study design, this paper aimed to understand Kachin graduates' life experiences, subjective perspectives on unemployment, and career interests and challenges. Online interviews were conducted with seven participants who had graduated but remained unemployed for at least six months. The results showed that political instability, a downturn in the economy, and a mismatch between education and the job market were the key factors that contributed to the unemployment problem of Kachin graduates nowadays. The research also found that low self-esteem, social isolation, and financial problems are the major consequences of unemployment experienced by Kachin graduates. The majority agreed that they had career interests in self-employed business but faced the challenges of lacking economic capital. In conclusion, the systems of social institutions were the key factors causing the unemployment problems of Kachin's young graduates; therefore, structural reforms are required to achieve lasting change. Putting this into context, unemployed Kachin graduates should try to be job creators at an individual level and in cooperated means rather than being job seekers or employees.
Estudio de los procesos fonológicos en niños sordos prelocutivos con implante coclear
Authors: Díaz Fresno Estefania , Martínez López Verónica , Núñez Batalla Faustino
Published: June 2024

El presente trabajo tenía como principal objetivo analizar y comparar la frecuencia y naturaleza de los procesos fonológicos de simplificación de 19 niños sordos prelocutivos con implante coclear (IC) de edad auditiva entre 3;0 y 4;6 años con un grupo de 160 niños normooyentes. Un segundo objetivo era determinar si la naturaleza y frecuencia de los procesos fonológicos variaba en función del método de elicitación en los niños con IC. Todos los participantes fueron grabados en conversación espontánea, las cuales se transcribieron y analizaron con los programas del paquete CLAN del Proyecto CHILDES. Para el análisis se adoptó el paradigma de los procesos fonológicos, evaluando el desarrollo a partir de un índice de error fonológico calculado a partir del total de procesos producidos y el total de palabras en el habla espontánea. Además, a los participantes con IC se les administró la prueba Evaluación Fonológica del Habla Infantil. Los participantes con IC presentan un índice de error fonológico mayor que sus iguales de edad auditiva en todos los grupos de edad, lo que implicaría un desarrollo fonológico más lento. En relación a la naturaleza de los procesos, encuentran más dificultades en los procesos que reducen la complejidad estructural de las palabras seguidos de los de sustitución. No se han observado diferencias significativas entre los grupos de edad auditiva en las clases de procesos en función del método de elicitación. Se enfatiza en el diagnóstico precoz de la sordera y el uso del implante coclear para un adecuado desarrollo fonológico.
Bilingüismo y discapacidad intelectual: habilidades lingüísticas y metalingüísticas, en castellano y en catalán, de hablantes con el síndrome Prader-Willi
Authors: Garcia-Alcaraz Estela , M. Liceras Juana
Published: June 2024

Este estudio investiga las habilidades lingüísticas y metalingüísticas de bilingües de castellano y catalán con discapacidad intelectual ligada a síndromes genéticos. A los participantes se les administraron pruebas estandarizadas y una prueba experimental. Respecto a esta última, adoptando el marco cognitivo metalingüístico de Bialystok y colaboradores, ocho bilingües con síndrome Prader-Willi completaron, tanto en castellano como en catalán, una tarea de juicios de gramaticalidad que manipulaba la gramaticalidad y la plausibilidad semántica de los ítems experimentales. Como resultado, la tarea contenía oraciones que incluían diferentes niveles de conocimiento lingüístico y habilidades de control ejecutivo. Trabajos previos reflejan que los bilingües con desarrollo típico muestran (i) resultados similares en ambas lenguas en aquellas oraciones que requieren una alta exigencia de control ejecutivo pero un bajo conocimiento lingüístico (medida metalingüística) y (ii) mejores resultados en la lengua dominante en aquellas oraciones que requieren un alto conocimiento lingüístico pero una baja exigencia de control ejecutivo (medida lingüística). Los resultados obtenidos reflejan que los bilingües incluidos en este estudio muestran habilidades lingüísticas y metalingüísticas comparables en las dos lenguas.
The Effect of Compensation, Motivation, and Work Discipline on Employee Performance at PT. Agro Artha Surya with Job Satisfaction as an Intervening Variable
Authors: Usu Idrus , Yakup Yakup , Lamuda Ilyas , Rahayu Leni
Published: June 2024

The aim of this research is to determine the relationship between the variables of compensation, motivation, and work discipline on the variables of job satisfaction and performance. Data collection methods include observation, questionnaires, and documentation. Using PLS analytical tools, the research results indicate that: 1) Compensation does not have a significant effect on employee performance, 2) Motivation has a positive and significant effect on employee performance, 3) Work discipline does not have a significant effect on employee performance, 4) Job satisfaction has a positive and significant effect on employee performance, 5) Compensation has a positive and significant effect on job satisfaction, 6) Motivation has a positive and significant effect on job satisfaction, 7) Work discipline has a positive and significant effect on job satisfaction, 8) Job satisfaction can mediate the effect of compensation on employee performance, 9) Job satisfaction can mediate the effect of motivation on employee performance, 10) Job satisfaction can mediate the effect of work discipline on employee performance.
Câncer de Mama Associado à Gestação
Authors: Moraes Salvador Silva Henrique , Martins de Araújo Campos Linhares Letícia , Fernanda da Motta Sperotto Valadares Gontijo Maria , Tadeu Campos de Avelar José , Augusto Silva Magalhães Costa Maurício , Dias Salvador Anna
Published: June 2024

O câncer de mama associado à gestação é definido como todo câncer de mama diagnosticado em mulheres durante a gestação, no primeiro ano pós parto ou enquanto ocorre a amamentação. Apesar do efeito protetor contra o câncer de mama a longo prazo, a gravidez, enquanto vigente, aumenta transitoriamente o risco desse mesmo câncer pelas altas exponenciais nas taxas hormonais que fazem parte da fisiologia desse período. Tal aumento de risco vem sendo agravado pela tendência atual da população feminina em gestar mais tardiamente, o que torna maior a prevalência do câncer de mama relacionado à gestação, afecção ainda incomum, com cerca de três casos a cada 10.000 partos, mas que demanda cada vez maior atenção por parte dos ginecologistas obstetras e mastologistas assistentes. O objetivo deste artigo é revisar o tema, abrangendo a epidemiologia, clínica, diagnóstico, tratamento e prognóstico nesse cenário.
Taxa de infecção e mortalidade por COVID-19 em pacientes ortopédicos operados em unidade hospitalar no Rio de Janeiro durante a pandemia
Authors: Carminatti Thiago , Gabriel de Cerqueira Campos Villardi João , Mandarino Marcelo , Erthal de Paula Rafael , Serra Cruz Raphael , Marques Villardi Alfredo
Published: June 2024

A pandemia pelo SARS-CoV-2 alterou o fluxo hospitalar nas unidades de atendi¬mento médico em todo o mundo, com di¬minuição drástica no número de cirurgias ortopédicas. Procedimentos eletivos foram, em sua grande maioria, suspensos, sendo mantidas apenas as consultas e cirurgias de emergência. O presente estudo buscou ava¬liar as taxas de mortalidade de pacientes ortopédicos internados no Hospital São Vi¬cente de Paulo (HSVP) durante os 15 me¬ses de pandemia (de março de 2020 a maio de 2021), além de determinar as causas de internação, estabelecendo uma comparação com os dados existentes na literatura. Fluxos de atendimento e protocolos de prevenção e tratamento foram postos em prática basea¬dos na literatura vigente.
Deprem Afeti Çerçevesinde Hayvanlar ve İdarenin Sorumluluğu
Authors: Mutlu Azer Ebru
Published: June 2024

6 Şubat 2023 Kahramanmaraş depremleriyle afet yönetimi ve idarenin bu konudaki sorumluluğu gündem olmuştur. Deprem gibi afetlerden sadece insanlar değil, hayvanlar da ağır şekilde etkilenmiştir. İnsanların temel haklarından olan yaşam hakkı, hayvanlar için de evrensel bir değer olarak kabul edilmiştir. Afet yönetimi, insanların, başlarına gelebilecek afet durumlarını tanımaları, afetlerden haberdar olabilmeleri, afetler meydana geldiğinde etkilenmemeleri ya da en az şekilde etkilenmelerini sağlamak için, afet öncesi hazırlık, planlama, korunma, afet sırası ve sonrasında tespit, müdahale, iyileştirme, yeniden yapılandırma gibi süreçleri içeren hizmetlerdir. Uluslararası eylem planları, özellikle kırılgan ve güçsüz gurupların, modern ve bütünleşik afet yönetimlerinde ayrı bir özenle düzenlenmesi öngörülmüştür. İnsanların yükledikleri anlam ne olursa olsun, canlı varlıklar olarak savunmasız ve örgütlenme kabiliyetinden yoksun hayvanların da afetlerde yaşam hakları korunmalı ve refahı sağlanmalıdır. Olağan koşullar bir yana, olağanüstü koşullarda hayvanlar, insanlara muhtaçtır. Her ne kadar 1982 Anayasası hayvanlarla ilgili doğrudan bir düzenleme içermese de uluslararası mevzuatı temel alarak hazırlanmış olan 5199 sayılı Hayvanları Koruma Kanunu ana mevzuattır. Türk Medeni Kanununa göre hayvanlar bir hakkın öznesi değil, süjesi yani konusu olarak ele alınan, sahiplenilen, ekonomik değeri olan birer eşyadır. Afet yönetimi mevzuatı incelendiğinde hayvanlarla ilgili düzenlemelerin yönetmelik ve plan düzeyinde kaldığı, pratiğe yansımadığı görülmektedir. Hakkın süjesi olarak ele alınan hayvanların deprem gibi afetlerde zarar görmeleri durumunda idarenin sorumluluğu, hayvanın sahipli olup olmamasına göre değişmektedir. Sahipsiz hayvanların sorumluluğunu pratik hukukta üstlenen bir merci bulunmamaktadır. Bu çalışma, fikri, idari ve hukuki altyapının oluşturulması adına, hayvanların afet yönetiminde konumunun belirlenmesinde, iyileştirilmesinde ve pratiğe geçirilmesinde yol açmayı hedeflemektedir.
The Production of Medically Important Bioactive Compounds by a Newly Discovered Fungi Species (Purpureocillium Species) - PP537396
Authors: M. O. Ngene , C. O. Anyamene , C. U. Ezebialu , B. Okorie , T. Ajogwu
Published: June 2024

The clog in the wheel of progress in management of infectious diseases has necessitated a continuous search for suitable bioactive agents for desired relief. Thus this work was to specifically screen previously isolated, newly discovered fungi species for bioactive agents. The fungi species – Purpureocillium sp was used to produce a crude antibiotic substance, extracted with acetone and tested on clinical isolates – Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans. The result of zones of inhibition was 20mm, 15mm, 16mm, 0mm and 20mm in order of listing of the organisms. The result of GC-MS test pin-points these compounds – t-9-octadecenoic acid, oleic acid, hexadecanoic acid methyl ester, z-9-octadecenamide, hexadecanoic acid and methylene chloride as been responsible for observed inhibition. The fungus was also used to produce a crude amylase and tested it on clinical organisms as above with no antibiotic activity. The enzyme activity of the crude enzyme was 70U/L. The antibiotic product holds a promise for a desired drug for mixed microbial infection just like the enzyme which can be coupled to a nano silver particle for drug delivery.
Simple Colourimetric Method and Development of A Colour Kit for on-the-spot Azelnidipine Estimation using A Smartphone Application, with Comparison to the UV-Spectroscopic Method
Authors: Suthar Pallavi , Mashru Rajshree
Published: June 2024

In the proposed research paper, a simple and accurate colorimetric method has been developed for the estimation of Azelnidipine in bulk. Instead of a traditional UV spectrophotometer, the proposed method measures the colour intensity of a solution using a smartphone camera and an application. This colorimetric method was found to be linear in the concentration range of 2µg/ml to 10µg/ml with an r2 value of 0.9993. The limits of detection (LOD) and quantification (LOQ) were found to be 0.024µg/ml and 0.068µg/ml, respectively.
Method Development and Validation of Alcaftadine Drug in Bulk and Dosage Form by RP-HPLC
Authors: R. Andhale Vidya , Gaware Vinayak
Published: June 2024

RP-HPLC method until now no analytical method by RP-HPLC was reported for its determination in bulk drug and in pharmaceutical dosage forms. Hence, in the present study, a new, sensitive, suitable and robust reversed-phase high performance liquid chromatography method was developed and validated for the determination of Alcaftadine in bulk drug and in dosage form. In RP-HPLC method, Water: Methanol 0.1% OPA. (80:20 %V/V) was used as mobile phase, at a flow rate of 1.0 ml/min, on RP-HPLC system containing UV- detector with Openlab Ezchrom workstation Software with Water Kromasil C18 column (250 mm x 4.6mm ID; 5μm) & column oven temp is 40ºC. The Wavelength was carried out at 282 nm. The method gave suitable retention time i.e. 8 min for Alcaftadine. The results of analysis in the method were validated in terms of Filter study, Solution stability, specificity, Linearity, accuracy and range, precision (Repeatability and intermediate precision), limit of detection, limit of quantification and robustness. A simple and precise method was developed for the assay of Alcaftadine in bulk drug and in Dosage form. The method need regular reagents for doing analysis and also less time consuming, it can be performed routinely in industry for routine analysis of bulk drug and marketed product of Alcaftadine.
A RP-HPLC approach to Bioanalytical Method Development and Validation: A Review
Authors: Naik Nunsavathu Sambasiva , Thangabalan B.
Published: June 2024

Bioanalytical method development is the process of creating a procedure to enable a compound of interest to be identified and quantified in a biological matrix. A compound can often be measured by several methods and the choice of analytical method involves many considerations. Analysis of drugs and their metabolites in a biological matrix is carried out using different extraction techniques like liquid-liquid extraction, solid phase extraction (SPE) and protein precipitation from these extraction methods samples are spiked with calibration (reference) standards and using quality control (QC) samples. These methods and choice of analytical method describes the process of method development and includes sampling, sample preparation, separation, detection and evaluation of the results. The developed process is then validated. These bioanalytical validations play a significant role in evaluation and interpretation of bioavailability, bioequivalence, pharmacokinetic, and toxicokinetic studies. In which different parameters like accuracy, precision, selectivity, sensitivity, reproducibility, and stability are performed.
Metoprolol succinate sustained release tablet: A review
Authors: D. Gangurde Praful , L. Pandit Rutik , P. Walekar Rutik , B. Chavan Prasad , R. Bashamlool Zahed , M. Salve Priyanka , M. Narwate Balaji
Published: June 2024

The main Purpose of existing investigation is to formulate and evaluate the sustained released tablet of Metoprolol Succinate using different polymer. Metoprolol Succinate is a β1-adrenergic receptor antagonist employed as an anti-arrhythmic, antianginal, antihypertensive. These content 99.0% to 101.0% (dried substance) appearance of Metoprolol Succinate is white or almost white, crystalline powder. Prolonged release tablet of Metoprolol Succinate were developed employing polymers. The globe is now becoming more and more interested in natural medications and excipients. The fact that these natural materials are chemically inert, nontoxic, less expensive, biodegradable, and readily accessible gives them several advantages over synthetic ones. Due to their excellent water-swellability, non-toxicity, low cost, and free availability, gums and mucilages are intriguing polymers for the creation of medicinal formulations. Gums and mucilages find applications in tablet formula as binders due to their adhesive nature. They impart cohesiveness to the powder mass and convert them into granules, which are further compressed into tablets.
The Next Pandemic
Authors: Haider Rehan
Published: June 2024

Dementia is a innovative and irreversible situation that represents a important mission to fitness and social care offerings round the world. An Alzheimer's Research fee file by using the college of Oxford in 2010 suggests that there are simply over 820,000 humans in the U.K. residing with dementia. This quantity is projected to upward shove to over 1 million via 2021 and over 1.7million through 2051, due to the Uk's getting old population. It is estimated that 670 zero household and buddies are appearing as most important carers The incidence of each early and late-onset dementia will increase with age has dementia, rising to 1in 6 human beings over 80 years and 1 in 3 of these aged over 75 years. It is greater frequent in a lady than in men. Over 17,000 younger humans (below the age of 65 years) in the UK have dementia. This is referred to as early-onset or young-onset dementia. An estimated two 0.33 of Care domestic residents have some shape of dementia however two 0.33 of all the human beings with dementia in the UK stay in the community. Approximately a quarter of Hospital beds are occupied through humans over the age of sixty five years with dementia. In 2010 the monetary fee of dementia to the NHS, nearby authorities, and households used to be 23 billion kilos per year. Greater than cancer(12 billion kilos per year) and coronary heart sickness (8 billion kilos per year) combined, and this is estimated to develop to 27 billion kilos by way of 2018. The term' dementia ' is used to describe a series of signs that may additionally encompass reminiscence loss, planning, problem-solving, language, communication, and reasoning difficulties alongside with adjustments in mood or behavior. There is regularly an related deterioration in the person's capability to lift out things to do of every day living. The most frequent kind of dementia money owed for about two to three instances and is barely greater frequent in ladies than men. The sickness is named after Dr. Alois Alzheimer's a German neurologist who described the Genius pathology of a 51years - historical female who died of a 'dementing type' sickness in 1907. The 'Amyloid cascade Hypothesis' has been proposed as the reason of AD through Klafki. et.al. This is based totally on proof that suggests that AD is related with a number types of extraordinary cloth inside the brain- neurofibrillary tangles and amyloid plaques, this impacts how nerve cells work and talk with every other, lowering the stage of chemical messengers and cells to die.
A Recent Advances in Drug Delivery to Brain- A Review
Authors: Jimidi Bhaskar Shailaja
Published: June 2024

The most distressing fact about delivery of drugs to the CNS is the presence of blood brain barrier that have a tendency to impair the drug distribution and denotes the major impediment for the development of CNS drugs. Neuropeptides and many drugs which are hydrophilic in nature, possibly will encompass the intricacy while passing the blood brain barrier. The net amount of delivered drug and its capability to gain access to the pertinent target sites are the main considering points for CNS drug development. In order to distribute the drugs into the CNS via passing the blood brain barrier. Finally, one particular area that is often neglected in brain drug barrier delivery is the influence of aging on the BBB, which is captured in this review based on the limited studies in the literature.
ГЕНДЕРНИЙ АСПЕКТ КОНЦЕПТУ ВІДПУСТКА / VACATION
Authors: БОНДАР Т. Г. , КИСЕЛЮК Н. П.
Published: June 2024

Статтю присвячено дослідженню гендерних особливостей наповнення концепту ВІДПУСТКА / VACATION в українській та американській лінгвокультурах. Для виокремлення концептуальних ознак досліджуваного концепту у січні–лютому 2024 р. було проведено вільний асоціативний експеримент, який дав можливість отримати спонтанні й неупереджені реакції респондентів, що є ключовими для дослідження способу мислення носіїв мови. В експерименті взяло участь 100 респондентів (50 українців та 50 американців), яким було запропоновано опитування у Google формах. Респонденти вказували свою стать, вік та асоціації на слово-стимул. Було отримано 249 асоціацій на слово-стимул відпустка та 248 асоціацій на стимул vacation. За допомогою аналізу частотності отриманих реакцій було виділено одиниці, які утворюють ядро, базовий шар, ближню периферію та дальню периферію концепту ВІДПУСТКА / VACATION. При порівняльному аналізі реакцій, отриманих від жінок та чоловіків, автори не виявили значних гендерних відмінностей у сприйнятті концепту ВІДПУСТКА / VACATION. Респонденти різної статі часто давали однакові слова-реакції. Проте останні відрізнялися частотністю, що означало різний ступінь їх значимості для жінок та чоловіків. Експеримент показав, що у свідомості українських жінок центральними концептуальними ознаками досліджуваного концепту є ‘відпочинок’ та ‘море’; чоловіки виокремили одну головну ознаку – ‘відпочинок’. Найчастотнішою для американських жінок була асоціація relaxation, яка й утворила ядро концепту. У частині експерименту з американськими чоловіками найчастотніші були реакції relaxation та travel. Автори показали, що вільний асоціативний експеримент уможливлює виокремлення і порівняння ознак досліджуваного концепту у свідомості представників різних лінгвокультур. Було доведено, що концепт ВІДПУСТКА / VACATION є актуальним як для українців, так і для американців. Ядро концепту утворює ознака ‘відпочинок/ relaxation’.