bluuebunny/crossref_metadata_2025 huggingface dataset:
User Experience of Virtual Heritage Tours with 360° Photos: A Study of the Chapel of Dolores in Icod de los Vinos
Authors: Meier Cecile , Saorín Jose Luis , Díaz Parrilla Silvia , Bonnet de León Alejandro , Melián Díaz Dámari
Published: May 2024

Virtual tours with 360 photos present a quick, easy and accessible way to create immersive experiences. The visualization on diverse devices provides a user experience that can be different. A virtual tour with 360 photos of the Chapel of Dolores (Tenerife) has been created. Access is limited to specific days, so the creation of a virtual tour allows you to visit it at any time; in addition, a pilot test has been carried out with students of the degree of restoration and conservation of cultural heritage in order to measure the user experience of the virtual tour, depending on the device used. The participants took a virtual tour of the Dolores Chapel, first with a cell phone and then with the virtual reality headset, and then completed a user experience questionnaire. The results obtained comparing both visualization technologies are detailed, highlighting the fact that when using the virtual reality headset no better results are obtained on the immersion subscale; in addition, the visualization on a smartphone is more comfortable and obtains better results for consequences such as dizziness and vertigo. Therefore, it may be an interesting strategy to have simple versions that work quickly on cell phones.
Altered Serum Proteins Suggest Inflammation, Fibrogenesis and Angiogenesis in Adult Patients with a Fontan Circulation
Authors: Michel Miriam , Renaud David , Schmidt Ronny , Einkemmer Matthias , Laser Lea Valesca , Michel Erik , Dubowy Karl Otto , Karall Daniela , Laser Kai Thorsten , Scholl-Bürgi Sabine
Published: May 2024

Previous omics research in patients with complex congenital heart disease and single-ventricle circulation (irrespective of the stage of palliative repair) revealed alterations in cardiac and systemic metabolism, inter alia abnormalities in energy metabolism, and inflammation, oxidative stress or endothelial dysfunction. We employed an affinity-proteomics approach focused on cell surface markers, cytokines, and chemokines in the serum of 20 adult Fontan patients with a good functioning systemic left ventricle, and we 20 matched controls to reveal any specific processes on a cellular level. Analysis of 349 proteins revealed 4 altered protein levels related to chronic inflammation, with elevated levels of syndecan-1 and glycophorin-A, as well as decreased levels of leukemia inhibitory factor and nerve growth factor-ß in Fontan patients compared to controls. All in all, this means that Fontan circulation carries specific physiological and metabolic instabilities, including chronic inflammation, oxidative stress imbalance, and consequently, possible damage to cell structure and alterations in translational pathways. A combination of proteomics-based biomarkers and the traditional biomarkers (uric acid, γGT, and cholesterol) performed best in classification (patient vs. control). A metabolism- and signaling-based approach may be helpful for a better understanding of Fontan (patho-)physiology. Syndecan-1, glycophorin-A, leukemia inhibitory factor, and nerve growth factor-ß, especially in combination with uric acid, γGT, and cholesterol, might be interesting candidate parameters to complement traditional diagnostic imaging tools and the determination of traditional biomarkers, yielding a better understanding of the development of comorbidities in Fontan patients, and they may play a future role in the identification of targets to mitigate inflammation and comorbidities in Fontan patients.
Lon1 Inactivation Downregulates Autophagic Flux and Brassinosteroid Biogenesis, Modulating Mitochondrial Proportion and Seed Development in Arabidopsis
Authors: Song Ce , Hou Yuqi , Li Tiantian , Liu Yinyin , Wang Xian-Ao , Qu Wumei , Li Lei
Published: May 2024

Mitochondrial protein homeostasis is crucially regulated by protein degradation processes involving both mitochondrial proteases and cytosolic autophagy. However, it remains unclear how plant cells regulate autophagy in the scenario of lacking a major mitochondrial Lon1 protease. In this study, we observed a notable downregulation of core autophagy proteins in Arabidopsis Lon1 knockout mutant lon1-1 and lon1-2, supporting the alterations in the relative proportions of mitochondrial and vacuolar proteins over total proteins in the plant cells. To delve deeper into understanding the roles of the mitochondrial protease Lon1 and autophagy in maintaining mitochondrial protein homeostasis and plant development, we generated the lon1-2atg5-1 double mutant by incorporating the loss-of-function mutation of the autophagy core protein ATG5, known as atg5-1. The double mutant exhibited a blend of phenotypes, characterized by short plants and early senescence, mirroring those observed in the individual single mutants. Accordingly, distinct transcriptome alterations were evident in each of the single mutants, while the double mutant displayed a unique amalgamation of transcriptional responses. Heightened severity, particularly evident in reduced seed numbers and abnormal embryo development, was observed in the double mutant. Notably, aberrations in protein storage vacuoles (PSVs) and oil bodies were evident in the single and double mutants. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of genes concurrently downregulated in lon1-2, atg5-1, and lon1-2atg5-1 unveiled a significant suppression of genes associated with brassinosteroid (BR) biosynthesis and homeostasis. This downregulation likely contributes to the observed abnormalities in seed and embryo development in the mutants.
Preharvest Elicitors as a Tool to Enhance Bioactive Compounds and Quality of Both Peel and Pulp of Yellow Pitahaya (Selenicereus megalanthus Haw.) at Harvest and during Postharvest Storage
Authors: Erazo-Lara Alex , García-Pastor María Emma , Padilla-González Pedro Antonio , Valero Daniel , Serrano María
Published: May 2024

Yellow pitahaya is a tropical fruit that has gained popularity in recent years. Natural elicitors are compounds that can stimulate the resistance and quality of fruits. The objective of this study was to evaluate the effects of natural elicitors, methyl salicylate (MeSa), methyl jasmonate (JaMe), salicylic acid (SA) and oxalic acid (OA) at concentrations of 0.1 mM (MeSa and JaMe) and 5 mM (SA and OA), applied to the yellow pitahaya fruits under greenhouse conditions. After full blossom, four applications were made with a frequency of 15 days. At the time of harvest and after storage, the following variables were evaluated: firmness (whole fruit), total soluble solids (TSS), total acidity (TA), phenolics and carotenoids (in the pulp), while phenolics, carotenoids, macronutrients and micronutrients were determined in the peel. The results showed MeSa advanced the fruit maturation, according to higher TSS, lower TA and firmness than MeJa-treated fruits, for which a delayed ripening process was shown. All treatments induced a higher polyphenolic concentration during storage. Regarding the alternative use of the peel as a by-product, the application of natural elicitors significantly increased the content of polyphenols, carotenoids, macronutrients and micronutrients in the peel, especially MeSa, which can be used as a bioactive compound in the food industry. In conclusion, the results indicate that natural elicitors can be an alternative to improve the quality and shelf life of yellow pitahaya fruits.
Review: Deep Learning-Based Survival Analysis of Omics and Clinicopathological Data
Authors: Sidorova Julia , Lozano Juan Jose
Published: May 2024

The 2017–2024 period has been prolific in the area of the algorithms for deep-based survival analysis. We have searched the answers to the following three questions. (1) Is there a new “gold standard” already in clinical data analysis? (2) Does the DL component lead to a notably improved performance? (3) Are there tangible benefits of deep-based survival that are not directly attainable with non-deep methods? We have analyzed and compared the selected influential algorithms devised for two types of input: clinicopathological (a small set of numeric, binary and categorical) and omics data (numeric and extremely high dimensional with a pronounced p >> n complication).
The Association of Serum Uric Acid with Risk of Obstructive Sleep Apnea: The Korean National Health and Nutrition Examination Survey 2019–2021
Authors: Park Su-Lim , Lim Jihye , Lee Ji-Ho
Published: May 2024

Upper airway collapse and apneas in obstructive sleep apnea (OSA) induce intermittent hypercapnia and hypoxia, eventually contributing to excessive uric acid production. This study aimed to evaluate the association between hyperuricemia and OSA in the general population via analysis of the eighth KNHANES dataset (2019–2021). OSA risk was identified via the STOP-Bang questionnaire, with a score ≥3 indicating high risk. Among 11,981 total participants, 4572 (38.2%) had a high OSA risk. Participants with a high OSA risk had higher uric acid levels compared to those with a low risk (5.5 ± 1.4 mg/dL vs. 4.8 ± 1.2 mg/dL, p < 0.001). Serum uric acid levels were positively correlated with STOP-Bang score (r: 0.317, p < 0.001). Multivariate analysis revealed that hyperuricemia was associated with a high OSA risk after adjusting for confounders (odds ratio: 1.30, 95%CI: 1.11–1.53, p = 0.001). Therefore, serum uric acid levels are significantly higher in those with a high OSA risk and correlate with the risk of OSA. Further, hyperuricemia is an independently associated risk factor for high OSA risk. More research is warranted to evaluate the long-term clinical outcomes of hyperuricemia in OSA and to determine whether treatment targeting hyperuricemia is effective in the clinical course of OSA.
The Preparation of Crumpled Graphene Oxide Balls and Research in Tribological Properties
Authors: Zhang Lili , Zhang Zhengrui , Gao Xi’an , Liao Hao
Published: May 2024

In this study, crumpled graphene oxide balls (CGBs) were prepared via capillary compression using a rapidly evaporating aerosol droplet method. The CGBs were observed using scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), and Raman spectroscopy. The size distributions of crumpled particles were obtained using a laser nanometer particle size analyzer (DLS). The dispersibility of the water and the ionic liquid (IL) was tested by ultrasonic dispersion. The tribological properties of water or ionic liquids containing crumpled graphene oxide ball additives (W/IL-CGB) were tested by a reciprocating friction tester and compared with water/ionic liquids with graphene oxide. The morphology of the wear scar was observed by a three-dimensional optical microscope and its lubrication mechanism was analyzed. The results show that the CGBs were successfully prepared by rapid evaporation of aerosol droplets, and the obtained CGBs were crumpled paper spheres. The CGBs had good water dispersion and ionic liquid dispersion, and IL-CGB has excellent anti-friction and anti-wear effects on steel–steel friction pairs. During the friction process, the CGB was adsorbed at the interface of the steel–steel friction pair to form a protective layer, which avoids the direct contact of the friction pair, thereby reducing friction and wear.
Diatom Biosilica Functionalised with Metabolically Deposited Cerium Oxide Nanoparticles
Authors: Wojtczak Izabela , Brzozowska Weronika , Trykowski Grzegorz , Sprynskyy Myroslav
Published: May 2024

This study introduces a novel approach to synthesising a three-dimensional (3D) micro-nanostructured amorphous biosilica. The biosilica is coated with cerium oxide nanoparticles obtained from laboratory-grown unicellular photosynthetic algae (diatoms) doped metabolically with cerium. This unique method utilises the ability of diatom cells to absorb cerium metabolically and deposit it on their silica exoskeleton as cerium oxide nanoparticles. The resulting composite (Ce-DBioSiO2) combines the unique structural and photonic properties of diatom biosilica (DBioSiO2) with the functionality of immobilised CeO2 nanoparticles. The kinetics of the cerium metabolic insertion by diatom cells and the physicochemical properties of the obtained composites were thoroughly investigated. The resulting Ce-DBioSiO2 composite exhibits intense Stokes fluorescence in the violet–blue region under ultraviolet (UV) irradiation and anti-Stokes intense violet and faint green emissions under the 800 nm near-infrared excitation with a xenon lamp at room temperature in an ambient atmosphere.
3D-Networks Based Polymer Composites for Multifunctional Thermal Management and Electromagnetic Protection: A Mini Review
Authors: Liu Houbao , Ji Xiaohu , Wang Wei , Zhou Lihua
Published: May 2024

The rapid development of miniaturized, high-frequency, and highly integrated microelectronic devices has brought about critical issues in electromagnetic compatibility and thermal management. In recent years, there has been significant interest in lightweight polymer-based composites that offer both electromagnetic interference (EMI) shielding and thermal conductivity. One promising approach involves constructing three-dimensional (3D) interconnection networks using functional fillers in the polymer matrix. These networks have been proven effective in enhancing the thermal and electrical conductivity of the composites. This mini-review focuses on the preparation and properties of 3D network-reinforced polymer composites, specifically those incorporating metal, carbon, ceramic, and hybrid networks. By comparing the effects of different filler types and distribution on the composite materials, the advantages of 3D interconnected conductive networks in polymer composites are highlighted. Additionally, this review addresses the challenges faced in the field of multifunctional thermal management and electromagnetic protection materials and provides insights into future development trends and application prospects of 3D structured composites.
Altered Arterial Stiffness, Ventricular–Arterial Coupling and Troponin Levels in Patients with Systemic Lupus Erythematosus
Authors: Kadoglou Nikolaos P. E. , Dimopoulou Alexandriani , Gkougkoudi Evangelia , Parperis Konstantinos
Published: May 2024

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease associated with an increased risk of cardiovascular diseases (CVDs), leading to elevated mortality rates among patients. We aimed to evaluate the levels of cardio–ankle vascular index (CAVI), global longitudinal strain (GLS), ventricular–arterial coupling (VAC), and high-sensitivity cardiac troponin I (hsTnI) in SLE patients and to explore their relationship with clinical parameters. Methods: This cross-sectional study enrolled 82 SLE patients without evident cardiac or kidney impairment and 41 age- and sex-matched healthy controls. We comparatively evaluated CAVI, GLS, VAC, and hsTnI between SLE patients and controls, and we assessed their association among SLE patients with disease activity based on the SELENA–SLEDAI Activity Index. Multivariate regression analysis was performed to identify independent predictors of CAVI and hsTnI within the SLE cohort. Results: In comparison to healthy controls, SLE patients presented with significantly higher CAVI, GLS, and hsTnI levels, while VAC was significantly reduced (p < 0.001). Furthermore, SLE patients with active disease (SELENA–SLEDAI ≥ 4) exhibited higher levels of CAVI and troponin than those with inactive disease (p < 0.001). SLEDAI was an independent predictor of CAVI, while VAC and SLEDAI were independent determinants of hsTnI in the SLE cohort. Conclusions: SLE patients displayed abnormal levels of CAVI, VAC, GLS, and troponin compared to healthy individuals. Our findings implicate the potential of those CV novel CVD risk factors to refine screening and therapeutic strategies for this specific population.
From Crossroads to Holistic Impact: Charting a Praxical Course for Transforming Theological Education in Africa
Authors: Msabah Barnabé Anzuruni
Published: May 2024

Theological education in Africa is currently at a crossroads and requires a thorough re-evaluation. The framework for teaching and learning introduced by missionaries during colonial times, which often prioritized Western perspectives and ignored indigenous African contexts, does not adequately address the complex issues and needs of African communities today. As a result, the impact of theological practice lacks both relevance and sustainability within grassroots communities. There is therefore a need for a theological framework that is more relevant, contextual, and responsive to the realities and aspirations of African people in the present context. This article advocates for the decolonization of theological education for a praxical approach rooted in lived experiences. It is essential to firmly anchor theological reflection and action in African traditions in order to effectively address contextual issues. This calls for action beyond academic reform towards meeting the pressing needs of the population. This article sheds light on the inadequacies of the colonial framework within theological education, serving as crucial indicators for holistic and sustainable transformation within the field. Case studies drawn from theological institutions, and local churches from selected countries in East, Central and Southern Africa provide nuanced insights into the importance of this transformative process.
Osteoimmunology: An Overview of the Interplay of the Immune System and the Bone Tissue in Fracture Healing
Authors: Ben Letaifa Rayan , Klaylat Tarek , Tarchala Magdalena , Gao Chan , Schneider Prism , Rosenzweig Derek H. , Martineau Paul A. , Gawri Rahul
Published: May 2024

Bone healing occurs through three consecutive and interdependent phases. While the acute inflammatory response is vital to fracture healing, chronic and systemic inflammation negatively affect the healing process. The bone tissue relies heavily on the immune system for its normal physiology and turnover. The interactions are more pronounced in injury states, such as fractures and autoimmune disorders. Recently, the field of osteoimmunology, the study of the molecular interplay of the immune and skeletal systems, has gained much-needed attention to develop new therapeutic strategies to accelerate fracture healing and prevent the complications of fracture healing. This review provides an overview of the process of fracture healing and discusses the role of immune cells, their interplay with the released cytokines, and the current state of the art in the field of osteoimmunology.
A Bosniak III Cyst Unmasking Tubulocystic Renal Cell Carcinoma in an Adolescent: Management with Selective Arterial Clamping and Robotic Enucleation
Authors: Della Corte Marcello , Cerchia Elisa , Allasia Marco , Marquis Alessandro , Linari Alessandra , Mandaletti Martina , Ruggiero Elena , Sterrantino Andrea , Quarello Paola , Catti Massimo , Fagioli Franca , Gontero Paolo , Gerocarni Nappo Simona
Published: May 2024

The Bosniak classification of renal cysts aims to provide a probabilistic risk assessment indicating the likelihood of malignancy from imaging findings. Originally designed to classify adult renal cysts based on computed tomography findings, the Bosniak classification has been extended to pediatric patients, with some adjustments made with the aim of accommodating magnetic resonance imaging (MRI) and ultrasonography (US). Bosniak IV lesions are rare in adolescents, indicating localized renal cell carcinoma and requiring surgical intervention. In contrast, Bosniak III lesions can be treated conservatively, although there is a lack of specific guidelines on their management. We present a case of a 14-year-old boy with a Bosniak III lesion, which was incidentally detected during the US evaluation of a left varicocele. After a 12-month follow-up, MRI revealed progression to a Bosniak IV cyst. Robot-assisted tumor enucleation was performed with selective artery clamping when the patient was 15. Histopathology showed tubulocystic renal cell carcinoma without adverse features. Immunocytochemistry supported a favorable prognosis of this rare tumor (<1% of renal tumor), thus obviating the need for adjuvant treatment. At the 18-month follow-up, no recurrence or distant metastasis were observed. This case highlights the importance of an aggressive treatment in persistent Bosniak III and Bosniak IV renal cysts in children and adolescents and the necessity to offer a nephron-sparing surgery.
Sentinel Lymph Node Mapping in Lung Cancer: A Pilot Study for the Detection of Micrometastases in Stage I Non-Small Cell Lung Cancer
Authors: Romano Gaetano , Zirafa Carmelina Cristina , Calabrò Fabrizia , Alì Greta , Manca Gianpiero , De Liperi Annalisa , Proietti Agnese , Manfredini Beatrice , Di Stefano Iosè , Marciano Andrea , Davini Federico , Volterrani Duccio , Melfi Franca
Published: May 2024

Lymphadenectomy represents a fundamental step in the staging and treatment of non-small cell lung cancer (NSCLC). To date, the extension of lymphadenectomy in early-stage NSCLC is a debated topic due to its possible complications. The detection of sentinel lymph nodes (SLNs) is a strategy that can improve the selection of patients in which a more extended lymphadenectomy is necessary. This pilot study aimed to refine lymph nodal staging in early-stage NSCLC patients who underwent robotic lung resection through the application of innovative intraoperative sentinel lymph node (SLN) identification and the pathological evaluation using one-step nucleic acid amplification (OSNA). Clinical N0 NSCLC patients planning to undergo robotic lung resection were selected. The day before surgery, all patients underwent radionuclide computed tomography (CT)-guided marking of the primary lung lesion and subsequently Single Photon Emission Computed Tomography (SPECT) to identify tracer migration and, consequently, the area with higher radioactivity. On the day of surgery, the lymph nodal radioactivity was detected intraoperatively using a gamma camera. SLN was defined as the lymph node with the highest numerical value of radioactivity. The OSNA amplification, detecting the mRNA of CK19, was used for the detection of nodal metastases in the lymph nodes, including SLN. From March to July 2021, a total of 8 patients (3 female; 5 male), with a mean age of 66 years (range 48–77), were enrolled in the study. No complications relating to the CT-guided marking or preoperative SPECT were found. An average of 5.3 lymph nodal stations were examined (range 2–8). N2 positivity was found in 3 out of 8 patients (37.5%). Consequently, pathological examination of lymph nodes with OSNA resulted in three upstages from the clinical IB stage to pathological IIIA stage. Moreover, in 1 patient (18%) with nodal upstaging, a positive node was intraoperatively identified as SLN. Comparing this protocol to the usual practice, no difference was found in terms of the operating time, conversion rate, and complication rate. Our preliminary experience suggests that sentinel lymph node detection, in association with the accurate pathological staging of cN0 patients achieved using OSNA, is safe and effective in the identification of metastasis, which is usually undetected by standard diagnostic methods.
Antecedents and Consequences of Health Literacy among Refugees and Migrants during the First Two Years of COVID-19: A Scoping Review
Authors: Markey Kathleen , Msowoya Uchizi , Burduladze Nino , Salsberg Jon , MacFarlane Anne , Dore Liz , Gilfoyle Meghan
Published: May 2024

Supporting refugee and migrant health has become a critical focus of healthcare policy. Developing and designing health literacy interventions that meet the needs of refugees and migrants is core to achieving this objective. This literature review sought to identify antecedents and consequences of health literacy among refugees and migrants during the first two years of the COVID-19 pandemic. We systematically searched nine electronic databases and numerous grey literature sources to identify studies published between December 2019 and March 2022. The antecedents (societal and environmental determinants, situational determinants, and personal determinants) and consequences of health literacy among refugees and migrants were mapped to a validated integrated health literacy model. Social and environmental determinants (n = 35) were the most reported antecedent influencing health literacy among refugees and migrants during the first two years of COVID-19. Language (n = 26) and culture (n = 16) were these determinants’ most frequently reported aspects. Situational determinants (n = 24) and personal determinants (n = 26) were less frequently identified factors influencing health literacy among refugees and migrants. Literacy (n = 11) and socioeconomic status (n = 8) were the most frequently reported aspects of personal determinants. Media use (n = 9) and family and peer influence (n = 7) were the most cited situational determinants reported. Refugees and migrants with higher levels of health literacy were more likely to use healthcare services, resulting in better health outcomes. The findings of this review reveal personal and situational factors that impacted health literacy among refugees and migrants during COVID-19 that require attention. However, the inadequate adaptation of health literacy interventions for linguistic and cultural diversity was a greater problem. Attention to this well-known aspect of public health preparedness and tailoring health literacy interventions to the needs of refugees and migrants during pandemics and other public health emergencies are paramount.
Müctehid Nazarında Makāsıdü’ş-Şerîanın Tahakkuk Yollarından Biri Olarak İstihsân
Authors: Çalışır Elif
Published: May 2024

Çalışmanın amacı Hanefî fukâhası tarafından tüm eleştirilere rağmen sahih istidlâl yöntemlerinden biri olarak kabul edilen istihsân metodunun başka bir usul konusu olan makāsıdü’ş-şerîa / İslâm hukukunun gayeleri ile ilişkisini tespit etmektir. Teknik olarak makâsıd terimiyle ifade edilmemiş olsa da literatürde geçen istihsân örnekleri bu perspektiften bakıldığında birtakım sonuçlara ulaşılmıştır. Öncelikle bir hükmün şer’î olması ile makāsıdü’ş-şerîa arasındaki münasebet ortaya konmuş, akabinde istihsân kavramına dair yapılan tanımlar ve izahlar teorik zeminde analiz edilmiştir. Daha sonra da Hanefî usulcülerin nazarında istihsânı kıyastan daha güçlü kılan şeyin ne olduğunu anlamak amacıyla pratik örnekler üzerinden ileri sürülen hukukî gerekçeler bir araya getirilerek incelenmiştir. Son tahlilde müçtehidin nazarında kıyasın uygulanması halinde ortaya çıkacak olan hükmün naslarda mündemiç olan manalara / makāsıdü’ş-şerîaya aykırı olduğu ve istihsân ile bu manalara en uygun olan hükme ulaşmayı ve böylece adaleti gerçekleştirmeyi hedeflediği gözlemlenmiştir. Zira İslâm hukukunda Şâri‘in gayelerine aykırı olarak vaz‘ edilen hiçbir hüküm âdil olarak kabul edilemez. Diğer taraftan istihsân hükmüyle genelde adaleti sağlamak özelde ise zorluğu kaldırmak / kolaylaştırmak, zarara mâni olmak, toplumun ihtiyaçlarını karşılamak ve kamu menfaatini sağlamak gibi bazı hukukî gayelerin öne çıktığı görülmüştür.
V2V Communication in Smart Traffic Systems: Current status, challenges and future perspectives
Authors: Yogha Bintoro Ketut Bayu , SDH Permana  , Ade Syahputra  , Yaddarabullah  , Budi Arifitama
Published: May 2024

Implementing V2V communication in intelligent traffic systems has been a topic of growing interest due to its potential to improve road safety and traffic flow. However, the widespread adoption of V2V communication in intelligent traffic systems could be enhanced by various challenges, such as infrastructure cost, security, and interoperability. These challenges must be addressed to improve the potential benefits of V2V communication. The problem statement of this study is to examine the potential benefits and challenges of V2V communication in intelligent traffic systems and provide insights into the current state of the art in V2V communication research. The proposed approach is to conduct a literature review of recent research on V2V communication in intelligent traffic systems to identify the potential benefits and challenges of V2V communication and the current state of the art in V2V communication research. The study aims to contribute to the field by comprehensively understanding the implementation of V2V communication in intelligent traffic systems and informing potential future research in this area. V2V communication can improve road safety and traffic flow in intelligent traffic systems. However, more research is needed to address the challenges and develop advanced and cost-effective V2V communication systems.
Brand Awareness, Electronic Word-of-Mouth, and Viral Marketing's Effects on Purchase Decisions
Authors: Kinanding* Jalu , Nurrohim Hasa
Published: May 2024

This research aims to determine and analyze the influence of viral marketing, electronic word of mouth, and brand awareness on purchase decisions. This research is survey research with quantitative approach and data collection tools in the form of questionnaires. The population in this study consists of students in Sleman District, with 100 respondents as the sample using purposive sampling. The data analysis technique used is multiple linear regression with SPSS program. The result of this study show that viral marketing, electronic word of mouth, and brand awareness simultaneously has a positive and significant influence on purchase decisions and viral marketing, electronic word of mouth, and brand awareness partially has a positive and significant influence on purchase decisions. This research contributes to expanding theory and students because it adds references regarding the influence of viral marketing, electronic word of mouth, and brand awareness on purchase decisions at the Shopee Marketplace in Sleman Regency.
Keyword: Viral Marketing; Electronic Word of Mouth; Brand Awareness; Purchase Decision; Shopee
Optimizing Motivation: Leadership Style that Inspires the Work Environment
Authors: Dira Aldi Friyatna , Sawitri Ina , Abdulrahman Abdulrahman , Utomo* Kurniawan Prambudi
Published: May 2024

The purpose of the research is to determine the influence of each variable of leadership style and work environment on motivation, as well as to optimize these variables in order to enhance employee motivation. This research method employs quantitative descriptive analysis using SPSS V.26 on the results from 40 respondents. The findings from the employees of the Transportation Department and the community as users of related transportation services indicate that the variables of the work environment’s role and leadership style have a significant positive impact on employee motivation. Therefore, it is recommended that the Transportation Department (Dishub) of Bekasi City should continue to maintain a harmonious relationship between leaders and employees to improve performance, thereby producing effective and adequate transportation services to increase the satisfaction of the Bekasi City community as users of transportation services.
Keyword: Optimization; Work Environment; Leadership Style; Motivation; Employees
Capital Market Reaction to the Strengthening of the Rupiah Exchange Rate against the US Dollar Exchange Rate
Authors: Lubis* M Zaky Mubarak , Putra Gusti Dirga Alfakhri , Binti Mohamad Zam Zuriyati
Published: May 2024

The purpose of this study is to analyze the response of Indonesian capital markets to differences in average abnormal returns and average trading volume activity before and after the strengthening of the IDR/USD exchange rate. This study is a quantitative study using the event study method. The sample used consists of the stocks included in the LQ45 index. the most active stocks with a large daily trading volume. Hypothesis testing and paired t-test. The results of the hypothesis test show that: there is no significant difference in the average abnormal returns before and after the strengthening of the rupiah against the US dollar because are sig. (2-tailed) value of 0.417 > 0.05; there is no significant difference in the average trading volume activity before and after the strengthening of the rupiah against the US dollar because sig. (2-tailed) value of 0.080 >0.05.
Keyword: Market Reaction; Event Study; Abnormal Return; Trading Volume Activity; Exchange Rate
The Worth of Islamic Piety for High-Quality Work Performed by Employees without Fraud
Authors: Ilma Robbi Zidni
Published: May 2024

Employees are the most important aspect of every organization, whose success can be determined by its employees whether they have good work quality or not. Good work quality is supported by performance without Fraud. This study aims to determine the role of an employee's Islamic piety value in work quality without Fraud. This is a work with a qualitative research method with an exploratory writing style. Selection of informants using purposive sampling. The primary data presented comes from in-depth and literature study as secondary data. Test the validity of the data as stated in the Triangulation of Sources and Theories technique. For Islamic people, piety is very much related to Fraud prevention, and also every pious employee will implement the teachings of his religion to be professional (not cheating). This research provides an overview to the stakeholders of each organization to find out other aspects in optimizing the quality of work of its employees.
 Keyword: Syariah Economy; Management; Employees; Work Quality; Fraud
Sodium Caseinate–Tannic acid Antioxidant Complex act as a High Internal Phase Pickering Emulsions Stabilizer
Authors: Norabi Atefeh , Mashhadi Hesam , Tabibiazar Mahnaz , Hamishehkar Hamed
Published: May 2024

Background: Emulsion-based formulations have gained attention in food and pharmaceutical products due to their unique properties. However, their use in food product formulation faces problems because of phase separation and fat oxidation, which seriously reduces the quality of the product. Therefore, finding ways to increase the physical and oxidative stability of emulsions is valuable. This work aimed to assess of physicochemical properties of sodium caseinate (SC)-tannic acid (TA) complex treated with heating and ultrasonication as well as their efficiency in physical and oxidative stability of high internal phase Pickering emulsion (HIPPEs) as antioxidant colloidal particles. Methods: SC 1% (w/v) was mixed with a different concentration of TA (0.1, 0.3, 0.5, 0.7, 1% w/v) and the pH of solutions was adjusted to 9. The unheated, heat-treated, and ultrasonicated SC-TA complexes were analyzed to elucidate possible interaction using FTIR, fluorescence spectroscopy, and DSC. Finally, HIPPEs were prepared by mixing the prepared samples and soybean oil at a volume ratio of 25:75 v/v respectively. The microstructure of the most stable HIPPEs was assessed using SEM. Results: Based on the FTIR results the covalent bond in heat-treated SC-TA was formed via the Maillard reaction. In addition, the reduction of free amino groups confirms Schiff base formation. All treated SC-TA samples showed a superior ability to stabilize emulsion in comparison with native SC when used as an aqueous phase of HIPPEs. The long-term physical was observed in heat-treated SC-TA HIPPEs for over two months. In PEs stabilized by SC-TA complex nanoparticles, primary and secondary oxidation product levels were significantly lower than in SC alone. Conclusion: The fabricating antioxidant emulsions using heat-treated SC-TA are a good guarantee for the physical and oxidative stability of food formulations due to TA's intrinsic antioxidant properties and the protective role of SC-TA colloidal particles against coalescence.
Development and Characterization of a Novel Spray-Dried Powder for Inhalation of Cinacalcet HCl Nanoparticles
Authors: Mireskandari Katayoon , Rostamnezhad Mostafa , Darabi Majid , Rouini Mohammadreza , Vatanara Alireza
Published: May 2024

Background: Administering Cinacalcet HCl (CINA) can be challenging because of its low oral bioavailability (20 to 25%) due mainly to its high first-pass metabolism and poor aqueous solubility. However, nanosuspensions are an effective way of enhancing solubility by reducing size. Furthermore, pulmonary delivery of the drug as a promising alternative route can bypass the hepatic first-pass metabolism. Method: A CINA nanosuspension was produced by sonoprecipitation and optimized to achieve minimum particle size and polydispersity index (PDI). These nanosuspensions were then spray-dried with different types of sugars to form nano-in-micro composite particles. The particles were then analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR), and differential scanning calorimetry (DSC), and the dissolution rate, solubility, and in vitro aerosol deposition behavior were determined. Results: The particle size of nanosuspensions was in the range of 239.5 to 1281.8 nm and the size was dependent on the process parameters. The spray-dried microparticles had a smooth and spherical surface morphology. The particle size of the composite particles was in the range of 2 to 10 µm and the dissolution rate of processed powders was significantly higher than raw CINA powder. Its crystallinity was partially diminished and no polymorphic conversion were observed. The in vitro deposition study, using a twin-stage impinger (TSI), presented fine particle fractions up to 76.7 percent. Conclusion: The utilization of nano-in-micro composite particles as a pulmonary delivery system for CINA has shown great potential in enabling a more efficient drug delivery.
Lehrkräftebildung in Deutschland. Mängelverwaltung im Widerspruch zu KMK-Standards?
Authors: Korneck Friederike
Published: May 2024

Die bildungspolitischen Diskurse zum Mangel an adäquat ausgebildeten Lehrkräften in Deutschland werden durch den Widerspruch zwischen länderübergreifenden Standards für die Lehrkräftebildung und eine gleichzeitig unüberschaubare Vielfalt wenig regulierter Notmaßnahmen der Bundesländer zur Gewinnung von Lehrkräften ohne Lehramtsstudium geprägt. Dieser Beitrag zeichnet (am Beispiel des Fachs Physik) die Entwicklungen der letzten Jahre nach, ergänzt durch ausgewählte empirische Befunde zum Kompetenzerwerb von Absolvent*innen verschiedener Ausbildungswege.
Vorzeitiger Berufseinstieg ins Lehramt. Risiken für die Profession
Authors: Bacher Sabrina , Dittrich Ann-Kathrin , Kraler Christian , Schauer Gabriele , Schreiner Claudia
Published: May 2024

Aufgrund des aktuellen Lehrer*innenmangels arbeiten Lehramtsstudierende zunehmend als Lehrpersonen. Fraglich ist, ob dies zu einer eingeschränkten individuellen Professionalisierung sowie kollektiven Deprofessionalisierung des Lehrer*innenberufs führt und wie es infolge zu einer Reprofessionalisierung kommen kann. Bereits unterrichtende Lehramtsstudierende wurden leitfadengestützt zur eigenen Professionalisierung interviewt. Die Ergebnisse zeigen, dass Studierende den vorzeitigen Berufseinstieg als bereichernd wahrnehmen, jedoch eine Reflexion des eigenen Professionalisierungsprozesses fehlt.
Desafíos de actualización para profesionales de recursos humanos en el nuevo paradigma tecnológico
Authors: Mardones Espinosa María Regina
Published: May 2024

El avance tecnológico está cambiando de manera significativa los roles y responsabilidades en el trabajo ¿Cómo podremos equilibrar le eficiencia tecnológica con la necesidad humana de tener un trabajo significativo y satisfactorio? La gestión de personas se ve desafiada por el nuevo paradigma que emerge con la velocidad del avance tecnológico, el cual exige a las organizaciones adaptarse y ajustar las estrategias de personas para optimizar el talento y la productividad. Los expertos en gestión de recursos humanos deben modificar sus tácticas y procedimientos en esta era para mantenerse al día con el rápido ritmo de las mejoras tecnológicas (Sharma, 2018).
SMART HALAL SUPPLY CHAIN PERFORMANCE: INDONESIA FISHERY PORTS SUSTAINABLE
Authors: Himawan Abdurrahman Faris Indriya , Razik Muhammad Aslyzan , Mohd Zain Rosmaizura , Wan Mahmood Wan Hasrulnizzam
Published: May 2024

Performance plays a crucial role in a company's survival, as it determines its success rate. We conducted this research to design performance measurements for a retail business in Fish Landing Ports, utilizing the Halal Supply Chain Operation Reference. This approach aims to gauge the current value of the company's performance and offer recommendations for potential improvements. Until now, the company has not conducted performance measurement across all its business process networks, focusing solely on product sales and profit value. Therefore, the company conducted research using the SCOR (Supply Chain Operation Reference) method based on Islamic values, with the expectation of measuring supply chain performance more objectively and in detail to create competitive advantages. We use the AHP (Analytical Hierarchy Process) method to assign weights to each criterion in the SCOR design. The supply chain performance measurement design yields its results. We obtain 22 metrics, five of which are based on Islamic values and categorised into five main business processes: plan, source, make, deliver, and return, drawing on literature and expert opinions for guidance. We carry out the assessment using a normalisation process to equalise the scale of values on each metric. The performance measurement results are very satisfactory, with a value of 91.713144. However, four metrics still have low values, indicating the need for improvement proposals. Furthermore, the plan has the highest weight of 0.42, followed by deliver, source, and return, all of which have weights of 0.22, 0.22, and 0.14 respectively.
Analysis of Music Brand Similarity Levels Using a Visual Computing Approach
Authors: Joshima Jodhi , Hillary Maldric
Published: May 2024

Currently, many trademarks have emerged, especially for music equipment products circulating in the community. Especially in Indonesia, musical instrument brands with various models have emerged. The problem occurs when the brand is considered to resemble the original brand, which makes it uncomfortable for musicians. Even though the quality of the tone produced is not assessed from a brand perspective, it is felt by brand owners to be quite a violation of the code of ethics. This has an impact on marketing products that are considered genuine. In this paper, a concept will be proposed in determining whether a trademark is considered authentic in terms of the logo. Use of Visual Computing with SIFT and SURF algorithms. SIFT (Scale-Invariant Feature Transform) and SURF (Speeded-Up Robust Features) are two popular algorithms for feature extraction and matching in image processing. Both are frequently used in computer vision applications such as object detection, image matching, and object recognition. The results of this analysis will be used for musicians who want to buy musical equipment to be able to detect the logo to compare the success of a musical instrument product. The appropriateness of the quality itself will be discussed in a different discussion. The benefits that can be generated will make musicians, especially in Indonesia, more conscientious. The possibility of sorting so that you can like your own product will be very possible.
Hubungan Kepuasan Kerja Dengan Turnover Intention Pada Perawat Pegawai Negeri Sipil Dan Tenaga Kontrak Di Rumah Sakit Umum Daerah Talisayan
Authors: Mukaromah Siti , Muhadi Muhadi
Published: May 2024

Niat berhenti turnover intention pegawai yang tinggi adalah ukuran yang umum digunakan untuk mengukur permasalahan mendasar suatu organisasi. Kepuasan kerja merupakan satu diantara beberapa penyebab turnover intention dimana pegawai merasa tidak puas dengan berbagai aspek seperti pendapatan, beban pekerjaan, pengawasan dll. Penelitian ini adalah penelitian deskriptif analitik, yang dilakukan untuk mengetahui bagaimana hubungan kepuasan kerja dengan turnover intention perawat Pegawai Negeri Sipil  dan Tenaga kontrak di RSUD Talisayan, dilakukan dengan pendekatan crosssectional. Responden yang dilibatkan adalah seluruh perawat dengan jumlah 39 orang, dilaksanakan bulan November sd Desember 2023. Cara pengambilan data melalui kuisioner yang terdiri dari kepuasan kerja dan turnover intention. Untuk pengolahan data menggunakan uji chi-square SPSS 23 dengan nilai signifikansi kurang 0.05. Hasil penelitian menunjukkan bahwa  secara umum  perawat merasa puas dan  keinginan untuk meninggalkan pekerjaannya cukup rendah, diketahui  dari variabel kepuasan kerja yang  tidak puas 18 perawat (46,15%)  puas 21 perawat 53,84% dan untuk variabel turnover intention  tinggi ada 16 perawat 41,02% rendah 23 perawat 67,65%. Hasil uji crosstabs menunjukkkan nilai asymp.sig 0.00 atau p kurang 0.05 maka dapat disimpulkan Ho ditolak dan Ha diterima atau terdapat hubungan yang signifikan antara kepuasan kerja dengan turnover intention pada perawat PNS dan tenaga kontrak di RSUD Talisayan. Dalam penelitian ini saran yang dapat disampaikan pada pihak manajemen dalam upaya mencegah peningkatan turnover intention di RSUD Talisayan sebaiknya membuka ruang diskusi dengan pegawai sehingga jika ada keinginan atau harapan juga permasalahan dari pegawai dapat segera tersampaikan dan diupayakan untuk dicarikan solusinya.
Highly Efficient Clay Based Degumming Aid for Phosphorous Removal from Crude Palm Oil
Authors: Bajpai Indu , Pal Pawan , Bhasin Sanjeev
Published: May 2024

The removal of phosphorous from crude oil is a complex and necessary step to enhance the oxidative stability and shelf life of edible oil. In this aspect, the current work proposed clay based degumming aid for the removal of phosphorous from the crude palm oil during the bleaching process. The state of art qualitative and quantitative techniques was adopted for the study of physical and chemical properties of different raw materials and oil. A profound study on the stability of the degumming aid is based on the assessment of phosphorous removal efficiency with time (up to 6 months) and bleachability.  The results of current work revealed that clay based degumming aid is highly effective in removing phosphorous up to 96%. Additionally, the bleaching performance of clay-based aid is also palpable (around 45%), which influences the deodorization process of the crude palm oil positively. The clay based degumming aid eliminate separate degumming process with acids, which directly impact the oil processing time and cost. Overall, proposed clay based degumming aid is highly efficient, stable for long time and cost effective as well, for the removal of undesired phosphorous from the crude palm oil during the bleaching process.