bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of imaging features in contrast-enhanced magnetic resonance imaging of benign and malignant breast lesions
Authors: Kubota Kazunori , Fujioka Tomoyuki , Tateishi Ukihide , Mori Mio , Yashima Yuka , Yamaga Emi , Katsuta Leona , Yamaguchi Ken , Tozaki Mitsuhiro , Sasaki Michiro , Uematsu Takayoshi , Monzawa Shuichi , Isomoto Ichiro , Suzuki Mizuka , Satake Hiroko , Nakahara Hiroshi , Goto Mariko , Kikuchi Mari
Published: March 2024

Purpose

This study aimed to enhance the diagnostic accuracy of contrast-enhanced breast magnetic resonance imaging (MRI) using gadobutrol for differentiating benign breast lesions from malignant ones. Moreover, this study sought to address the limitations of current imaging techniques and criteria based on the Breast Imaging Reporting and Data System (BI-RADS).

Materials and Methods

In a multicenter retrospective study conducted in Japan, 200 women were included, comprising 100 with benign lesions and 100 with malignant lesions, all classified under BI-RADS categories 3 and 4. The MRI protocol included 3D fast gradient echo T1- weighted images with fat suppression, with gadobutrol as the contrast agent. The analysis involved evaluating patient and lesion characteristics, including age, size, location, fibroglandular tissue, background parenchymal enhancement (BPE), signal intensity, and the findings of mass and non-mass enhancement. In this study, univariate and multivariate logistic regression analyses were performed, along with decision tree analysis, to identify significant predictors for the classification of lesions.

Results

Differences in lesion characteristics were identified, which may influence malignancy risk. The multivariate logistic regression model revealed age, lesion location, shape, and signal intensity as significant predictors of malignancy. Decision tree analysis identified additional diagnostic factors, including lesion margin and BPE level. The decision tree models demonstrated high diagnostic accuracy, with the logistic regression model showing an area under the curve of 0.925 for masses and 0.829 for non-mass enhancements.

Conclusion

This study underscores the importance of integrating patient age, lesion location, and BPE level into the BI-RADS criteria to improve the differentiation between benign and malignant breast lesions. This approach could minimize unnecessary biopsies and enhance clinical decision-making in breast cancer diagnostics, highlighting the effectiveness of gadobutrol in breast MRI evaluations.
Current trends, limitations and future research in the fungi?
Authors: Hyde Kevin D. , Baldrian Petr , Chen Yanpeng , Thilini Chethana K. W. , De Hoog Sybren , Doilom Mingkwan , de Farias Antonio R. Gomes , Gonçalves Micael F. M. , Gonkhom Didsanutda , Gui Heng , Hilário Sandra , Hu Yuwei , Jayawardena Ruvishika S. , Khyaju Sabin , Kirk Paul M. , Kohout Petr , Luangharn Thatsanee , Maharachchikumbura Sajeewa S. N. , Manawasinghe Ishara S. , Mortimer Peter E. , Niego Allen Grace T. , Phonemany Monthien , Sandargo Birthe , Senanayake Indunil C. , Stadler Marc , Surup Frank , Thongklang Naritsada , Wanasinghe Dhanushka N. , Bahkali Ali H. , Walker Arttapon
Published: March 2024

The field of mycology has grown from an underappreciated subset of botany, to a valuable, modern scientific discipline. As this field of study has grown, there have been significant contributions to science, technology, and industry, highlighting the value of fungi in the modern era. This paper looks at the current research, along with the existing limitations, and suggests future areas where scientists can focus their efforts, in the field mycology. We show how fungi have become important emerging diseases in medical mycology. We discuss current trends and the potential of fungi in drug and novel compound discovery. We explore the current trends in phylogenomics, its potential, and outcomes and address the question of how phylogenomics can be applied in fungal ecology. In addition, the trends in functional genomics studies of fungi are discussed with their importance in unravelling the intricate mechanisms underlying fungal behaviour, interactions, and adaptations, paving the way for a comprehensive understanding of fungal biology. We look at the current research in building materials, how they can be used as carbon sinks, and how fungi can be used in biocircular economies. The numbers of fungi have always been of great interest and have often been written about and estimates have varied greatly. Thus, we discuss current trends and future research needs in order to obtain more reliable estimates. We address the aspects of machine learning (AI) and how it can be used in mycological research. Plant pathogens are affecting food production systems on a global scale, and as such, we look at the current trends and future research needed in this area, particularly in disease detection. We look at the latest data from High Throughput Sequencing studies and question if we are still gaining new knowledge at the same rate as before. A review of current trends in nanotechnology is provided and its future potential is addressed. The importance of Arbuscular Mycorrhizal Fungi is addressed and future trends are acknowledged. Fungal databases are becoming more and more important, and we therefore provide a review of the current major databases. Edible and medicinal fungi have a huge potential as food and medicines, especially in Asia and their prospects are discussed. Lifestyle changes in fungi (e.g., from endophytes, to pathogens, and/or saprobes) are also extremely important and a current research trend and are therefore addressed in this special issue of Fungal Diversity.
Using a Respondent-Type Matching-to-Sample Exclusion Training Procedure to Establish Equivalence Responding
Authors: Todd Jonathan , Keenan Mickey , Gallagher Stephen
Published: March 2024

An exclusion training procedure involves presenting a sample stimulus with an unrelated comparison stimulus that is presented alongside other comparison stimuli that previously have acquired a negative relation to the sample stimulus. Due to the already established negative comparisons, the participant selects the unrelated stimulus, establishing a relation between the two stimuli. Of the large body of research on exclusion, there has been no research conducted that has combined respondent conditioning with an exclusion training procedure. This study used a respondent-type matching-to-sample (ReTMTS) exclusion training procedure with probe trials to train 3, three-member equivalence classes. A–B relations were trained using the ReTMTS procedure, and A–C relations were trained via exclusion using the ReTMTS procedure. Of the 10 participants who reached the test phase, only 2 failed to reach the criterion required to demonstrate equivalence responding. These findings are discussed in the context of previous research on exclusion training.
K-stable smooth Fano threefolds of Picard rank two
Authors: Cheltsov Ivan , Denisova Elena , Fujita Kento
Published: March 2024

We prove that all smooth Fano threefolds in the familiesandare K-stable, and we also prove that smooth Fano threefolds in the familythat satisfy one very explicit generality condition are K-stable.
The Prohibition of Child Labour in Factories Revisited: Towards a Social History of Decommodification in the Early Nineteenth Century
Authors: Ruoss Matthias
Published: March 2024

This article examines the removal of children from factories and their integration into the school system in the early nineteenth century, using decommodification as a conceptual framework. The Swiss canton of Aargau serves as a case study – a region where the textile industry flourished and a liberal government came to power after the July Revolution, subsequently enforcing compulsory education. Through a nuanced exploration of diverse sources, the article argues that decommodification was a deeply contentious process marked by conflicts between working-class families, factory owners, the state, and the church. Simultaneously, these conflicts unleashed dynamic forces that coded working-class childhood in terms of age and gender. It is this transformational power that underscores the interpretative potential of decommodification as a constructive process of Vergesellschaftung (sociation). Beyond simply freeing children from labour obligations, the prohibition of factory work reintegrated them intricately into the social fabric of the economy.
Robotics goes PRISMA
Authors: Selvaggio Mario , Moccia Rocco , Arpenti Pierluigi , Caccavale Riccardo , Ruggiero Fabio , Cacace Jonathan , Ficuciello Fanny , Finzi Alberto , Lippiello Vincenzo , Villani Luigi , Siciliano Bruno
Published: March 2024

In this article, we review the main results achieved by the research activities carried out at PRISMA Lab of the University of Naples Federico II where, for 35 years, an interdisciplinary team of experts developed robots that are ultimately useful to humans. We summarize the key contributions made in the last decade in the six research areas of dynamic manipulation and locomotion, aerial robotics, human-robot interaction, artificial intelligence and cognitive robotics, industrial robotics, and medical robotics. After a brief overview of each research field, the most significant methodologies and results are reported and discussed, highlighting their cross-disciplinary and translational aspects. Finally, the potential future research directions identified are discussed.
Stress Balance in Synthetic Serpentinized Peridotites Deformed at Subduction Zone Pressures
Authors: Hilairet N. , Guignard J. , Ferrand T. P. , Merkel S. , Raterron P. , Ildefonse B. , Fadel A. , Crichton W.
Published: March 2024

Weak serpentine minerals affect the mechanical behavior of serpentinized peridotites at depth, and may play a significant role in deformation localization within subduction zones, at local or regional scale. Mixtures of olivine with 5, 10, 20 and 50 vol. % fraction of antigorite, proxies for serpentinized peridotites, were deformed in axial shortening geometry under high pressures (ca. 2–5 GPa) and moderate temperatures (ca. 350°C), with in situ stress and strain measurements using synchrotron X‐rays. We evaluate the average partitioning of stresses at the grains scale within each phase (mineral) of the aggregate and compare with pure olivine aggregates in the same conditions. The in situ stress balance is different between low antigorite contents up to 10 vol. %, and higher contents above 20 vol. %. Microstructure and stress levels suggest the deformation mechanisms under these experimental conditions are akin to (semi)brittle and frictional processes. Unlike when close to dehydration temperatures, hardening of the aggregate is observed at low serpentine fractions, due to an increase in local stress concentrations. Below and above the 10–20 vol. % threshold, the stress state in the aggregate corresponds to friction laws already measured for pure olivine aggregates and pure antigorite aggregates respectively. As expected, the behavior of the two‐phase aggregate does not evolve as calculated from simple iso‐stress or iso‐strain bounds, and calls for more advanced physical models of two‐phase mixtures.
Evaluation of computed tomography artefacts of carbon-fiber and titanium implants in patients with spinal oligometastatic disease undergoing stereotactic ablative radiotherapy
Authors: Rijs Zeger , Kawsar Khandkar Ali , Saha Priyanshu , van de Sande Michiel , Lui Darren
Published: March 2024

This study evaluated artefacts on computed tomography (CT) images using Hounsfield units (HU) in patients with spinal oligometastatic disease who received carbon-fiber (CF; n = 11) or titanium (n = 11) spine implants and underwent stereotactic ablative radiotherapy (SABR). Pre- and postoperative HU were measured at the vertebral body, pedicle, and spinal cord at three different levels: the lower instrumented vertebra, the level of metastatic spinal cord compression, and an uninvolved level. Areas measured at each level were delicately matched pre- and postoperatively. Significant differences in HU were observed at the vertebral body, the pedicle, and the spinal cord at the lowest instrumented vertebra level for both CF and titanium (average increase 1.54-fold and 5.11-fold respectively). At the metastatic spinal cord compression level, a trend towards a higher HU-increase was observed in titanium compared with CF treated patients (average increase 2.51-fold and 1.43-fold respectively). The relatively high postoperative HU-increase after insertion of titanium implants indicated CT artefacts, while the relatively low HU-increase of CF implants was not associated with artefacts. Less CT artefacts could facilitate an easier contouring phase in radiotherapy planning. In addition, we propose a CT artefact grading system based on postoperative HU-increase. This system could serve as a valuable tool in future research to assess if less CT artefacts lead to time savings during radiotherapy treatment planning and, potentially, to better tumoricidal effects and less adverse effects if particle therapy would be administered.
Inter hospital external validation of interpretable machine learning based triage score for the emergency department using common data model
Authors: Yu Jae Yong , Kim Doyeop , Yoon Sunyoung , Kim Taerim , Heo SeJin , Chang Hansol , Han Gab Soo , Jeong Kyung Won , Park Rae Woong , Gwon Jun Myung , Xie Feng , Ong Marcus Eng Hock , Ng Yih Yng , Joo Hyung Joon , Cha Won Chul
Published: March 2024

Emergency departments (ED) are complex, triage is a main task in the ED to prioritize patient with limited medical resources who need them most. Machine learning (ML) based ED triage tool, Score for Emergency Risk Prediction (SERP), was previously developed using an interpretable ML framework with single center. We aimed to develop SERP with 3 Korean multicenter cohorts based on common data model (CDM) without data sharing and compare performance with inter-hospital validation design. This retrospective cohort study included all adult emergency visit patients of 3 hospitals in Korea from 2016 to 2017. We adopted CDM for the standardized multicenter research. The outcome of interest was 2-day mortality after the patients’ ED visit. We developed each hospital SERP using interpretable ML framework and validated inter-hospital wisely. We accessed the performance of each hospital’s score based on some metrics considering data imbalance strategy. The study population for each hospital included 87,670, 83,363 and 54,423 ED visits from 2016 to 2017. The 2-day mortality rate were 0.51%, 0.56% and 0.65%. Validation results showed accurate for inter hospital validation which has at least AUROC of 0.899 (0.858–0.940). We developed multicenter based Interpretable ML model using CDM for 2-day mortality prediction and executed Inter-hospital external validation which showed enough high accuracy.
Oxytoxaceae are prorocentralean rather than peridinialean dinophytes and taxonomic clarification of heterotrophic Oxytoxum lohmannii (≡ “Amphidinium” crassum) by epitypification
Authors: Gottschling Marc , Wietkamp Stephan , Bantle Alexis , Tillmann Urban
Published: March 2024

During evolution of Dinophyceae, size reduction of the episome has occurred in several lineages (including unarmoured Amphidiniales and armoured Prorocentrales). One such species is Amphidinium crassum, whose taxonomic identity is elusive though showing morphological similarities with Oxytoxaceae (currently placed in armoured Peridiniales). Plankton samples were taken at the type locality of A. crassum in Kiel Bight (Baltic Sea) in order to establish monoclonal strains. The protist material was examined in detail using light and electron microscopy, and a long (2984 bp) ribosomal RNA sequence gained was part of a taxon sample comprising 206 specimen vouchers and representing the known molecular diversity of Dinophyceae. Cells of A. crassum were ovoid and exhibited a plate pattern po, 4′, 1a, 6′′, 5c, 4s, 5′′′, 1′′′′. In the molecular phylogeny, the species seemed to belong neither to Amphidiniales nor to Peridiniales but to Prorocentrales and clustered with other representatives of Oxytoxaceae. The morphological diversity of Prorocentrales appears thus expanded, and the group may include a number of previously unrecognised representatives unusually having five postcingular and only a single antapical plate. The taxonomic identity of A. crassum is clarified by epitypification, and the species notably exhibits both an apical pore and an additional epithecal pore.
Influence of nitrogen fertilization, seed inoculation and the synergistic effect of these treatments on soybean yields under conditions in south-western Poland
Authors: Serafin-Andrzejewska Magdalena , Jama-Rodzeńska Anna , Helios Waldemar , Kozak Marcin , Lewandowska Sylwia , Zalewski Dariusz , Kotecki Andrzej
Published: March 2024

Soybean, belonging to legumes, has a specific ability to biological nitrogen fixation, which can be reinforced by seeds inoculation. However, support with a starter dose of mineral nitrogen fertilizer may be necessary to achieve high seed yields. A four-year field experiment was conducted to determine the effect of mineral N fertilization (0, 30, 60 kg ha−1), seed inoculation with two commercial inoculants and combinations of these treatments on yield components and yielding of soybean in conditions of south-western part of Poland. The synergistic effect of mineral fertilization at dose 30 kg ha−1 and inoculation on soybean productivity was the most beneficial. Similar effects were observed when 60 kg N ha−1 was applied both separately and with inoculation. However, due to the environmental impact of mineral fertilizers and to promote plants to biological nitrogen fixation (BNF), it is advisable to use lower doses of N fertilizer (at 30 kg ha−1) and inoculate soybean seeds in agro- climatic conditions of south-western Poland. Therefore, based on this study we recommend to apply starter dose of N and inoculation.
Decoding the spread of non-indigenous fishes in the Mediterranean Sea
Authors: Vagenas Georgios , Karachle Paraskevi K. , Oikonomou Anthi , Stoumboudi Maria Th. , Zenetos Argyro
Published: March 2024

The ocean is dynamically changing due to the influence of climate processes and human activities. The construction of the Suez Canal in the late nineteenth century opened the Pandora’s box by facilitating the dispersal of Red Sea species in the Mediterranean Sea. In this study, we developed an open-source spatio-temporal numerical analysis framework to decodify the complex spread of Mediterranean non-indigenous fish species (NIS) that entered through the Suez Canal. We utilized 772 historical detection records of 130 NIS to disentangle their dynamic spread through space and time. The results indicated that species follow a north-westward trajectory with an average expansion time step of 2.5 years. Additionally, we estimated the overall time for a NIS to reach the Central Mediterranean Sea from the Suez Canal at approximately 22 years. Based on the analysis, more than half of the introduced fishes have been established in less than 10 years. Finally, we proceeded in the cross-validation of our results using actual spread patterns of invasive fishes of the Mediterranean Sea, resulting up to 90% of temporal and spatial agreement. The methodology and the findings presented herein may contribute to management initiatives in highly invaded regions around the globe.
Stimulus type and duration affect magnitude and evolution of flicker-induced hyperemia measured by laser speckle flowgraphy at the optic disc and peripapillary vessels
Authors: Aung Moe H. , Aleman Tomas S. , Garcia Arielle S. , McGeehan Brendan , Ying Gui-Shuang , Avery Robert A.
Published: March 2024

Neurovascular coupling is a vital mechanism employed by the cerebrovascular system, including the eye, to regulate blood flow in periods of neuronal activation. This study aims to investigate if laser speckle flowgraphy (LSFG) can detect coupling response elicited by flickering light stimuli and how variations in stimulus type and duration can affect the magnitude and evolution of blood flow in the optic nerve head (ONH) and peripapillary vessels. Healthy adults were exposed to two types of 10-Hz flicker stimuli: a photopic negative response-like stimulus (PhNR-S) or a visual evoked potential-like stimulus (VEP-S)—each presented in separate 10- and 60-s epochs. Both PhNR-S and VEP-S significantly increased ONH blood flow (p < 0.001) immediately after flicker cessation, with a trend of 60-s stimuli (PhNR-S = 11.6%; VEP-S = 10.4%) producing a larger response than 10-s stimuli (PhNR-S = 7.5%; VEP-S = 6.2%). Moreover, exposure to 60-s stimuli elicited a significantly prolonged ONH hyperemic response, especially with PhNR-S. Lastly, stimulation with either 60-s stimuli elicited a robust increase in blood flow within the peripapillary arterioles (p < 0.01) and venules (p < 0.01) as well. Flicker stimulation with common visual electrophysiology stimuli (PhNR-S and VEP-S) induced a demonstrable increase in ONH and peripapillary vessel blood flow, which varied with flicker duration. Our results validate that LSFG is a robust method to quantify flicker-induced hyperemic responses and to study neurovascular coupling in humans.
Mechanical and self-healing properties of cement paste containing incinerated sugarcane filter cake and Lysinibacillus sp. WH bacteria
Authors: Ditta Zerlinda Mara , Laohana Peerawat , Tanapongpisit Nantawat , Saenrang Wittawat , Boonlue Sophon , Sata Vanchai , Baalousha Mohammed , Chindaprasirt Prinya , Ekprasert Jindarat
Published: March 2024

Cement is the most widely used construction material due to its strength and affordability, but its production is energy intensive. Thus, the need to replace cement with widely available waste material such as incinerated black filter cake (IBFC) in order to reduce energy consumption and the associated CO2 emissions. However, because IBFC is a newly discovered cement replacement material, several parameters affecting the mechanical properties of IBFC-cement composite have not been thoroughly investigated yet. Thus, this work aims to investigate the impact of IBFC as a cement replacement and the addition of the calcifying bacterium Lysinibacillus sp. WH on the mechanical and self-healing properties of IBFC cement pastes. The properties of the IBFC-cement pastes were assessed by determining compressive strength, permeable void, water absorption, cement hydration product, and self-healing property. Increases in IBFC replacement reduced the durability of the cement pastes. The addition of the strain WH to IBFC cement pastes, resulting in biocement, increased the strength of the IBFC-cement composite. A 20% IBFC cement-replacement was determined to be the ideal ratio for producing biocement in this study, with a lower void percentage and water absorption value. Adding strain WH decreases pore sizes, densifies the matrix in ≤ 20% IBFC biocement, and enhances the formation of calcium silicate hydrate (C–S–H) and AFm ettringite phases. Biogenic CaCO3 and C–S–H significantly increase IBFC composite strength, especially at ≤ 20% IBFC replacement. Moreover, IBFC-cement composites with strain WH exhibit self-healing properties, with bacteria precipitating CaCO3 crystals to bridge cracks within two weeks. Overall, this work provides an approach to produce a "green/sustainable" cement using biologically enabled self-healing characteristics.
Hierarchical superstructure aerogels for in situ biofluid metabolomics
Authors: Chen Siyu , Pu Keyuan , Wang Yue , Su Yang , Qiu Jiamin , Wang Xin , Guo Kunbin , Hu Jun , Wei Huiwen , Wang Hongbiao , Wei Xiaolong , Chen Yuping , Lin Wen , Ni Wenxiu , Lin Yan , Chen Jiayang , Lai Samuel Kin-Man , Ng Kwan-Ming
Published: March 2024

A superstructure is designed for simultaneous metabolite enrichment, separation of interfering salt and direct biofluids analysis.
Ruthenium single-atom doping-driven modulation of Co3O4 spinel tetrahedral site 3d-orbital occupancy in lithium–oxygen batteries
Authors: Fan Yining , Li Ting , Li Bin , Hu Anjun , Li Dongfen , Li Kun , Yang Borui , Pan Yu , Liu Jing , Long Jianping
Published: March 2024

This work reveals theoretically and experimentally the internal mechanism of using Ru single atoms to control the electronic structure of tetrahedral sites in spinel Co3O4 to catalyze the operation of lithium–oxygen batteries (LOBs).
Guiding uniform Zn electrodeposition through regulating pressure for stable aqueous Zn batteries
Authors: Zhang Fenglin , Cai Ziyang , Liu Runtao , Sun Yang , Pan Huilin
Published: March 2024

Optimal axial pressure facilitates stabilization of interphasial chemistry and enhances Zn2+ transport at the electrode–electrolyte interface, thereby guiding uniform and dense Zn deposition in aqueous Zn batteries.
Synergistic vacancy defects and bandgap engineering in an Ag/S co-doped Bi2O3-based sulfur oxide catalyst for efficient hydrogen evolution
Authors: Su Zhengjie , Wu Xinru , Kuo Dong-Hau , Yang Baoqian , Wu Binghong , Chen Longyan , Zhang Pengkun , Lin Jinguo , Lu Dongfang , Chen Xiaoyun
Published: March 2024

Herein, an Ag/S co-doped Bi2O3-based sulfur oxide catalyst was prepared via a facile green method.
Microwave-assisted synthesis of polyoxometalate-Dy2O3 monolayer nanosheets and nanotubes
Authors: Dipalo Maria C. , Yu Biao , Cheng Xijun , Nie Siyang , Liu Junli , Shi Wenxiong , Zhang Fenghua , Liu Qingda , Wang Xun
Published: March 2024

We developed monolayer Dy2O3-PMA nanosheets and nanotubes based on microwave-assisted synthesis, with which high-energy input enabling faster and dynamically driven growth of nanomaterials, resulting in high-purity and narrow size distribution.
3D bridge-arch-structured dual-side evaporator for practical, all-weather water harvesting and desalination
Authors: Chen Meijie , Li Shuang , Chen Xingyu , Huang Yimou , Liu Bin , Yan Hongjie , Sheldon Brian W. , Li Qing , Shi Changmin
Published: March 2024

An efficient 3D bridge-arch structured dual-side evaporator was proposed for all-weather water harvesting via solar thermal and Joule heating, showing a solar evaporation rate of 4.10 kg m−2 h−1 and Joule heating evaporation rate of 6.50 kg m−2 h−1.
[001]-Oriented heteroepitaxy for fabricating emissive surface mounted metal–organic frameworks
Authors: Zhao Tonghan , Taghizade Narges , Fischer Jan C. , Richards Bryce S. , Howard Ian A.
Published: March 2024

A hybrid SURMOF with specific crystallographic [001] orientation is fabricated via step-by-step liquid-phase heteroepitaxial method. The preferential [001] orientation of Cu2(BDC)2(DABCO) is retained via Zn2(BDC)2(DABCO) to Zn2(ADC)2(BPy).
Polarized, color-selective and semi-transparent organic photodiode of aligned merocyanine H-aggregates
Authors: Schembri Tim , Kolb Leonhard , Stolte Matthias , Würthner Frank
Published: March 2024

Highly anisotropic layers of a dipolar merocyanine with optical dichroic ratios of >50 were deposited by solution shearing for simultaneously semitransparent (visible transmittance: 93%) and polarization-/color-selective organic photodiodes.
DHGL: Dynamic hypergraph‐based deep learning model for disease prediction
Authors: Qu Zhe , Sun Ziyou , Liu Ning , Xu Yonghui , Yang Xiaohui , Cui Lizhen
Published: March 2024

Electronic health record (EHR) data is crucial in providing comprehensive historical disease information for patients and is frequently utilized in health event prediction. However, current deep learning models that rely on EHR data encounter significant challenges. These include inadequate exploration of higher‐order relationships among diseases, a failure to capture dynamic relationships in existing relationship‐based disease prediction models, and insufficient utilization of patient symptom information. To address these limitations, a novel dynamic HyperGraph‐based deep learning model is introduced for disease prediction (DHGL) in this study. Initially, pertinent symptom information is extracted from patients to assign them with an initial embedding. Subsequently, sub‐hypergraphs are constructed to consider distinct patient cohorts rather than treating them as isolated entities. Ultimately, these hypergraphs are dynamized to gain a more nuanced understanding of patient relationships. The evaluation of DHGL on real‐world EHR datasets reveals its superiority over several state‐of‐the‐art baseline methods in terms of predictive accuracy.
Implementation of the export potential as a factor in sustainable development of the forest sector: regional aspect
Authors: Kapustina Y. , Yakovenko N.
Published: March 2024

At the present stage of economic development, international trade is becoming an arena for solving geopolitical problems. The implementation of the export potential in the context of the concept of sustainable development is based on a detailed analysis of trends in the export specialization of national economy priority sectors. The subject of the study is the regional forest sector. The provisions of the theory of comparative advantages served as a methodological basis. The article summarizes approaches to assessing the export potential, analyzes the commodity and geographical diversification of the Russian forest sector. The relevance of improving the analytical tools for assessing the sustainability of sectoral socio-economic systems is proved. The information basis of the study is official customs statistics. An analysis of the dynamics of exports made it possible to assess the impact of economic instruments, regulatory and managerial influences, and customspolicyon the development of the export potential of the forest sector. The index of Revealed comparative export advantage has a multiplicative character. It made it possible to obtain detailed information for the development and adjustment of strategies for territorial and sectoral development. The authorsidentified export specialization products of the forest sector of the Russian Federal Districts. An insufficient level of use of resource potential and a narrow specialization of most forested regions in products with low added value were stated.
Mutual influence of tourism and transport on the territory of "Sayan crossroads"
Authors: Kuklina M.V. , Krasnoshtanova N.E. , Demidov A.E.
Published: March 2024

In our study, we focused our attention on identifying general patterns and specific regional features of the development of tourism, transport infrastructure and the interests of indigenous peoples on the territory of the Sayan Crossroads. Regional and federal authorities consider it necessary to develop tourism in the areas under consideration in order to improve the quality of life of the local population. A sharp increase in the number of tourists, as well as the transport development of the territory without taking into account the opinion of the local population, can lead to serious contradictions and conflicts, contribute to the degradation and destruction of traditional cultural landscapes. Thus, in the system "local population - transport - tourism" there are complex multi-aspect and multi-vector connections and mutual influences. These connections have both common fundamental patterns and their own regional and local features. All of them must be understood and taken into account when planning the sustainable development of the territory. Field work was carried out in the Okinsky district of Buryatia, Todzhinsky kozhuun of Tyva, in the Khankh somon of Khubsugul aimag of Mongolia in 2021-2022. Keywords: Okinsky district, Todzhunsky kozhuun, Todzha, Oka, Sayan crossroads, tourism, transport infrastructure
Interaction model of forestry enterprises with society and environment
Authors: Medvedev Sergey , Zyryanov Mikhail , Dudin Pavel
Published: March 2024

The article presents the results of a study on the interaction between timber enterprises, society, and the environment. Currently, a business's effectiveness is determined by its ability to resolve conflicts between social, environmental, and economic spheres. The purpose of this work was to obtain and substantiate an adequate model of enterprise interaction with society and the environment. The main method used was analysis. Several models were developed to describe the interaction of the studied objects. The text provides a justification for existing conflicts in the work of timber enterprises. The development of technological aspects is proposed as a direction to transition the forest industry to a qualitatively new level of functioning. Several proposed key transformations can contribute to the transition to a balanced interaction model between the enterprise and the environment. The model of interaction between timber enterprises, society, and the environment is developed, highlighting areas for both increase and decrease. The study concludes that a balanced policy, oriented towards achieving sustainable results over time, is necessary for timber enterprises to achieve long-term success. It is important to consider the interests of future generations and the surrounding society, as this approach will only become more important in the future.
Ecological groups of reptiles found in Bukhara region
Authors: Rayimov A.R. , Turaev M.M. , Aripov B.F.
Published: March 2024

Any environmental problems observed around the world, especially, anthropogenic factors have an impact on nature, including the number and bioecological characteristics of reptiles. In particular, the expansion of the types and scale of human economic activity and its increasing impact on environment require the organization of in-depth scientific research of the diversity of reptile species, the ecology of their distribution and the organization of protection. Since the second half of the last century, issues related to environmental protection and conservation of biodiversity have become of universal importance in terms of their scale and fedtscheukoi, Agama Lehmanni, Ophisaurus apodus, Eryx miliaris, Echis carinatus, Testudo horsfieldi, Phrynocephalus mustaceus, Gymnodactylus caspius, Natrix tesselata, Vipera ursini, Phrynocephalus interscapularis Eremias velox, Eremias grammica.
The significance of technical hemp cultivation and biometric indicators of the researched varieties in Uzbekistan
Authors: Gaybullaev G.S. , Eshonqulov B.M. , Hatamov M. , Fayzimurodov J.B. , Kim Veronika
Published: March 2024

Technical cannabis - the variety planted in the Havos region, which contains up to 0.2% of the narcotic substance tetrahydrocannabinol, is brought from Europe, that is, from France, and it is being cultivated in a very small amount of narcotics. It is necessary to plant the brought collection in the nursery, study it in every way and select varieties suitable for the soil and climate conditions of our Republic, and based on these, create new varieties with the help of selection methods and develop agrotechnology for their cultivation. In our experiment with cannabis plants, we studied the yield characteristics of the seeds, the biometric indicators of the varieties and the amount of oil released from the seeds.
Evaluation of the effectiveness of the use of differentiated technologies in crop production
Authors: Zhuravleva Larisa
Published: March 2024

The principle of differentiated technologies is to process fields in accordance with the actual needs of agricultural crops at each specific point of the field. The purpose of the work was to analyze the effectiveness of the use of differentiated fertilization technologies in the cultivation of winter wheat of the Moskovskaya variety. Field research was carried out according to three options: without the use of fertilizers, the application of fertilizers by a single norm and by differentiated technology. The use of fertilizers using traditional fertilization technology allowed for an increase in yield of almost 32% compared to the control (without fertilizers).With the use of differentiated technologies, the yield increased by 82%.
Influence of topsoil manure mix on affects germination in Pea and Onion seeds
Authors: Zhurlov Oleg , Zhurlova Maria
Published: March 2024

Nutrient-rich southern chernozems have lost a significant part of their fertility during their exploitation in agrocenoses. The decrease in the fertility of the surface layer of soils in the steppe landscapes of the Orenburg Cis-Urals contributed to a decrease in the yield of grain crops and an increase in the volume of applied mineral fertilizers. The use of reverse technology of mechanical tillage contributed to the weathering of the surface fertile soil layer and its degradation. Plowing of the Orenburg steppes for agrocenoses led to a decrease in the number of wild ungulates and their adaptation to new living conditions in agrocenoses. Our work was devoted to modeling the process of the influence of the soil-manure mixture of the surface layer of southern chernozem and the manure of large phytophages on the germination of pea and onion seeds in laboratory conditions. Changes in the composition of bacterial communities during the preparation of the soil-manure mixture are one of the factors influencing the germination and morphometric growth parameters of onion and pea seeds. There is no doubt that the nutritional composition of the manure of large phytophages is of decisive importance for stimulating the growth of onions and peas. However, the differences we have shown in the bacterial composition of soil-manure mixtures of two large phytophages raises the problem of increasing or decreasing the nutritional value of the soil-manure mixture depending on the composition of the microbial communities of the manure of large phytophages.
Modeling carbon nutrition and photosynthesis taking into account plant stomatal resistance
Authors: Vorotyntsev Alexander
Published: March 2024

A differential-algebraic system of equations of carbon dioxide transport and photosynthesis in vegetation is formulated for mathematical analysis of the influence on productivity and water regime of plant populations. A simple semi-empirical algebraic approximation of the true photosynthesis function is constructed for the quasi-stationary solution of the system, including the influence of stomatal regulation, leaf index, absorbed photosynthetically active radiation, and temperature.
Methodology and mechanisms of sustainable development of agricultural companies on the basis of competitive advantages
Authors: Valiyeva Saltanat , Nurgaliyeva Zhanna , Pritula Raissa , Ostryanina Tatyana , Malyarenko Olga , Zhussupov Rysbek
Published: March 2024

The problems of ensuring sustainable development of agricultural companies on the basis of their competitive advantages have been studied. The methodology of formation and development of mechanisms of sustainable development of the company on the basis of its competitive advantages is developed and the block diagram of the algorithm realising is drawn up. The developed methodology is based on the comparison of indicators of the managed and the leading company of the agro-industrial complex and the elimination of the difference on the basis of the development of sustainable development mechanisms and competitive advantages. The concept of sustainability of agricultural companies, which defines the state of continuous, dynamic development and ensures the current and future market demand for quality agricultural products, The mechanisms of sustainable development of the company are considered as an organisational subsystem of the campaign, implementing its activities to ensure sustainable development. The originality of the study lies in the development of an algorithm for the implementation of the proposed methodology for the formation of the mechanism of sustainable development of the company, providing sustainable development of the company on the basis of its competitive advantages and benchmarking.
Modeling marketing communication in a farm plant care information system
Authors: Altunina Yulia , Chernova Vera
Published: March 2024

The article substantiates the need to use the marketing communication channel in specialised software for agriculture. The purpose of such a channel is to provide information to farmers about the availability of planting material, technical means that ensure the processes of the production cycle, services of specialized contractors, etc. in the market. The content of such a channel in the software should be personalized, i.e., based on the user profile and his activity in the software product. The aim of the research is to create an information model that demonstrates the transformation of software product processes when implementing a marketing communication channel. To realize the goal, all the key objects involved in the mentioned processes are established, all the links between them are established. The obtained results became the basis for using the method of information modeling in order to create a model of the process of interaction between users of the system, its main modules and the module responsible for generating content for marketing communication. The developed model shows the information flows arising between the subjects of interaction during the realization of the functional capabilities of the information system.
An important role in the variety of active sludge composition in wastewater treatment
Authors: Pardayev Shamedin , Toshov Hayot , Shamsiyev Naim
Published: March 2024

Informtion on wastewater treatment methods in the Bukhara city treatment plant is provided. Organic matter in the water that has passed through the mechanical cleaning system is bacteria in the aero tank. It is fully described that microorganisms are decomposed using active sludge. In Aero tank, active sludge index is 200-250 mg/l and for the first time more than 127 of its species have been identified. It has been studied that biogenic substances can be cleaned up to 90-97% with the help of the algae.
Determination and assessment of the groundwater table and mineralization in irrigated areas (Xojeli district, Republic of Karakalpakstan)
Authors: Kulmatov Rashid , Alimov Atabek , Opp Christian
Published: March 2024

Irrigated areas in the Aral Sea Basin are becoming highly saline due to the ascendant groundwater table and groundwater mineralization. This, in turn, leads to a decrease in soil fertility in agriculture and negatively affects the food security of basin countries. In the research work, seasonal changes in the groundwater table and mineralization during the periods of 2015 and 2023 were evaluated on the irrigated lands of the Xojeli district in the Republic of Karakalpakstan (Uzbekistan). Field monitoring was carried out on 142 observation wells using traditional methods of measuring the groundwater table and mineralization. Then, the obtained data was statistically analyzed, and maps based on the geoinformation system (GIS) were created by the inverse distance weighting (IDW) interpolation method for the study period. Furthermore, a correlation coefficient analysis was applied to find a relationship between climatic patterns, and groundwater table, and mineralization. Results based on statistical analysis present steady fluctuations in the groundwater table and wild fluctuations in mineralization over a period of nine years. The average water table below surface and mineralization in April was determined by 1.55 m and 2.94 g/l, in July by 1.78 m and 2.96 g/l, and in October by 2.18 m and 2.56 g/l. The visual maps created in accordance with the GIS-based method show that average values for the groundwater table in the irrigated areas were 1.5–2 m and 2–3 m (57.9% and 27.8%), and mineralization was 1-3 g/l and 3-5 g/l (62.4% and 36.5%). A correlation coefficient (r) shows a low relationship between the chosen variables.
Issues of ecological impact of irrigation works and development of new lands in the steppe region
Authors: Orziyev Mahmud , Usmanov Murtoz
Published: March 2024

In this article, during the rule of the Russian Empire, the digging of new ditches, the development of new lands, especially desert areas, farming on newly acquired lands, the ecological impact of excavated canals and acquired lands, the issues of erosion of the banks of the "Emperor Nicholas I" canal are analyzed based on the materials of the "Turkestan Collection" done.
On the issue of assessing the importance of associated petroleum gas as a valuable raw material in the fields of the Khanty-Mansiysk Autonomous Okrug
Authors: Pogrebnaya Irina , Mikhailova Svetlana
Published: March 2024

the purpose of this article is to consider the problem of flaring associated petroleum gas (APG), as one of the most relevant and acute for our country, because Russia occupies a leading position in the world in terms of APG flaring volumes. Burning APG leads to environmental damage, contributes to the greenhouse effect, harms public health, as well as the country's economy - valuable chemical raw materials and energy resources are simply thrown away. According to the Ministry of Natural Resources of the Russian Federation, out of 55 billion m3 of APG produced annually in Russia, only 26% (14 billion m3) is sent for processing, 47% (26 billion m3) goes to the needs of the fields, or is written off as technological losses and 27 % (15 billion m3) is flared.
Scientific Research Project Curriculum: A Clever Teaching Method of “Scientific Research Nurturing Teaching”
Authors: Liu Hui , Yu Qiuhao , Cui Zhoumeng , Yu Deng-Guang
Published: March 2024

Higher education shoulders the task of cultivating high-level professionals with innovative spirit and practical ability. Undergraduate education plays a vital role as the beginning of higher education. However, the existing undergraduate teaching content is relatively outdated and the teaching mode is simple, making it difficult to stimulate students’ learning interest and improve their innovative practical ability. The scientific research project curriculum is rich in content and diverse in teaching forms, which can not only expand the teaching mode but also enrich and supplement professional knowledge. In this work, the teaching method of scientific research project curriculum is investigated in the investigated discipline - Material Science and Engineering. It is demonstrated that the introduction of scientific rlesearch project curriculum into undergraduate education or graduate education can help students improve their independent learning enthusiasm, professional practical skills, and innovative thinking abilities in the process of solving practical scientific research problems. Particularly, a project course about electrospun nanofibers is demonstrated to be a facile approach for achieving a comprehensive practice training for students. In a word scientific research project curriculum has proven to be a good teaching method for achieving “scientific research nurturing teaching”.
Issues and Strategies in English Translation of Public Notices in Light of Text Typology Theory: A Case Study of Zhoushan City
Authors: Jia Qinglin , Hou Jiang , Chen Zhaorong , Fu Mengnan
Published: March 2024

This paper focuses on the English translations of public notices in Zhoushan City, which plays a crucial role in facilitating international tourism development. Zhoushan City boasts abundant tourism resources and aims to attract a global audience. However, the current English translations of public notices have various issues that hinder the comprehensive advancement of public services and the overall upgrading of the tourism industry. Drawing on Newmark’s theory of text type translation, this study examines the existing problems in English translations and proposes suitable solutions to enhance the effectiveness and accuracy of the translations. By standardizing the English translations of public notices, Zhoushan City can create a favorable cultural and tourism environment, improve the international quality of urban tourism, and establish itself as a prominent tourism and cultural brand.