bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis de capacidades para la activación de sistemas agroalimentarios localizados: el caso del cacao de la Provincia de Occidente (Boyacá, Colombia)
Authors: Rodríguez Pinzón Nubia Yolanda , Aranda Camacho Yesid
Published: February 2024

The territorial innovation systems (TIS) require proposing actions that lead to strengthening the capacities of the local actors to activate localized agri-food systems (SYAL). The objective of the research has been the evaluated capacities for knowledge management (KM) that can condition the activation of the SYAL. A multi-criteria model was developed and subjected to estimation with experts, and in its evaluation a choice experiment was used to evaluate the capacities for the CG stakeholders SYAL of cocoa in the western province of Boyacá, Colombia. The low performance of individual capacities for reciprocity, agreement, trust, and solidarity, as well as communication as an organizational capacity of producer organizations, merit the design of actions to strengthen them that lead to the activation of the SYAL.
First Results of Tracking of the Juvenile Egyptian Vultures from Karatau, Kazakhstan
Authors:   Russian Raptor Research and Conservation Network, Karyakin Igor V. ,   Sibecocenter LLC, Knizhov Kirill I. ,   Russian Raptor Research and Conservation Network; Sibecocenter LLC, Nikolenko Elvira G. ,   Russian Raptor Research and Conservation Network; Sibecocenter LLC, Shiriaev Oleg V. ,   Russian Raptor Research and Conservation Network; Sibecocenter LLC, Pulikova Genriyetta I. ,   Biodiversity Research and Conservation Center Community Trust, Kaptyonkina Alyona G. ,   Biodiversity Research and Conservation Center Community Trust; Institute of Zoology of the Republic of Kazakhstan, Andreyenkova Natalya G. ,   Institute of Molecular and Cellular Biology SB RAS
Published: February 2024

Using GPS/GSM tracking, the migrations of 6 juvenile Egyptian Vultures (Neophron percnopterus) tagged in the Karatau Mountains (Kazakhstan) in 2022 were studied. From birds in 2022 and 2023, 36063 locations were obtained. The post-fledging period from the moment of leaving the nest until the start of migration lasted from 15 to 35 days, and it was shorter in females and longer in males. The area of individual sites on the natal territory defined as the minimum convex polygon (MCP 100%) varied from 1.3 to 1560 km2, averaging (n=6) 419.2±610.5 km2. The start of the migration of Egyptian Vultures occurred from September 5 to 23, which lasted 13–28 days. The distances of the autumn migration of vultures to the wintering site were 2038.8–3995.9, on average 2764.87±674.11 km at location points and 1160.3–1893.2, on average 1656.45±255.53 km in a straight line. All birds successfully reached their wintering grounds in the Indus basin. By the middle of the 2nd winter, 3 birds remained in Pakistani Kashmir on the border with India (1 ind.) and Rajasthan (2 ind.). Two Egyptian Vultures were captured by local residents in Pakistan, one with tracker was released, and the tracker was removed from the other and handed over to intelligence agencies and destroyed. The area covered by movements of the Egyptian Vultures at the wintering site during the 100 days was: MCP – 4512.8–62110.3, on average 23264.1±22371.7 km2 and Kernel 95% – 239.4–7429.0, on average 2390.91±2625.8 km2.
Implicações da síndrome de burnout na saúde mental dos enfermeiros da atenção primária à saúde
Authors:   Centro de Atenção Psicossocial - CAPS II, Santos Edilson Lima dos , Begnini Marciele ,   Hospital São Vicente de Paulo, Prigol Adrieli Carla ,   Hospital São Vicente de Paulo
Published: February 2024

Objetivo: Identificar a sobrecarga de trabalho dos enfermeiros da atenção primária em saúde e suas implicações para saúde mental. Método: Trata-se e uma revisão bibliográfica do tipo revisão integrativa, a partir de publicações científicas indexadas, por meio das bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (Scielo) e na National Center for Biotechnology Information (Pubmed), publicados no período de 2017 a 2022. Resultados: Foram utilizados 07 artigos na revisão, os quais respondiam à pergunta de pesquisa. diante dos estudos analisados, identificou-se que os enfermeiros da atenção primária em saúde, apresentam multitarefas, seja assistencial, gerencial e de ensino, o que ocasiona uma sobrecarga de trabalho, levando-os a altos níveis de estresse, ansiedade e angústia, o que acarreta a uma sobrecarga emocional. Conclusão: O enfermeiro da atenção primária em saúde tem multitarefas o que acarreta uma sobrecarga de trabalho, levando a um desgaste emocional com efeitos negativos, o que interfere diretamente na sua produtividade e na assistência prestada ao paciente.
SOLVABILITY OF A FOUR DIMENSIONAL SYSTEM OF DIFFERENCE EQUATIONS
Authors: DEVECİOĞLU Şule , KARA Merve
Published: February 2024

In this study, we investigate the following four-dimensional difference equations system

{█(u_n=(αu_(n-3) t_(n-2)+β)/(γv_(n-1) t_(n-2) u_(n-3) ), @v_n=(αv_(n-3) u_(n-2)+β)/(γw_(n-1) u_(n-2) v_(n-3) ),n∈N_0,@w_n=(αw_(n-3) v_(n-2)+β)/(γt_(n-1) v_(n-2) w_(n-3) ), @t_n=(αt_(n-3) w_(n-2)+β)/(γu_(n-1) w_(n-2) t_(n-3) ), )┤

where the initial values u_(-d),v_(-d),w_(-d),t_(-d), d∈{1,2,3} and the parameters α,β,γ are real numbers. Then, we obtain the solutions of system of third-order difference equations in explicit form. In addition, the solutions according to some special cases of the parameters are examined. Finally, numerical examples are given to demonstrate the theoretical results.
Tabagismo e fatores associados em trabalhadores de uma universidade pública
Authors:   Universidade Estadual de Campinas, Neves Mayza Luzia dos Santos , Araujo Estefany Mayara Sousa ,   Universidade Estadual de Campinas, Pagamicce Leila Tassia ,   Universidade Estadual de Campinas, São-João Thaís Moreira ,   Universidade Estadual de Campinas, Cornelio Marilia Estevam ,   Universidade Estadual de Campinas, Ceolim Maria Filomena ,   Universidade Estadual de Campinas, Andrechuk Carla Renata Silva ,   Universidade Estadual de Campinas, Rodrigues Roberta Cunha Matheus ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O tabagismo é responsável por cerca de 8 milhões de mortes por ano e é considerado a principal causa de doenças, incapacidades e mortes evitáveis no mundo. Objetivo: Verificar a prevalência e fatores associados ao tabagismo entre trabalhadores de uma universidade pública. Método: Trata-se de um estudo transversal (CAAE:28971320.50000.5404), com dados parciais de 415 trabalhadores ativos (média de idade 44,6 anos, 57,6% sexo feminino), com idade entre 18 a 59 anos na aleatorização. Os participantes foram convidados, via e-mail institucional, e preencheram instrumento de caracterização sociodemográfica e clínica, Índice da Qualidade do Sono de Pittsburg, Índice de gravidade de insônia e o Questionário de Berlim, em formulário digital (REDCap). Os dados antropométricos e a pressão arterial foram coletados de forma presencial. Foi utilizado o teste do Qui-quadrado para avaliar a existência de associações entre as variáveis, considerando-se um intervalo de confiança de 95% (p < 0,05). Resultados: Observou-se que 7,3% eram fumantes ativos e 7,3% ex-fumantes. Os fatores associados ao tabagismo foram sexo masculino, hipertensão arterial, obesidade, risco para apneia obstrutiva do sono e a gravidade da insônia. Conclusão: A prevalência de tabagismo foi menor que a média nacional. Dentre os fatores identificados, a maioria são passíveis de tratamento ou modificações. O tabagismo deve ser investigado, sendo fundamental a proposta de estratégias preventivas e de cessação, visando a redução de prejuízo à saúde dos trabalhadores.
Desordem informacional e a prática baseada em evidências em tempos de COVID-19
Authors:   Universidade Estadual de Campinas, Dias Ana Paula de Oliveira , Silva Eliete Maria ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: Durante a pandemia da COVID-19 os profissionais de saúde, que também são consumidores de informação, tiveram a tripla jornada de prevenir a doença, tratar as pessoas contaminadas e lidar com desinformações provenientes de diferentes fontes. Distinguir informações verdadeiras das falsas não só se tornou uma tarefa difícil, como também pode levar à confusão pública, aumentar a polarização política e minar a confiança do público na mídia e nas instituições. Objetivos: Compreender a desordem informacional na visão dos profissionais de saúde. Método: Pesquisa qualitativa, resultado de uma dissertação de mestrado, com 15 profissionais de saúde de uma instituição pública, em um município de São Paulo. No período de novembro de 2021 a fevereiro de 2022 foram realizadas entrevistas remotas semi-estruturadas e as percepções dos profissionais foram analisadas tematicamente, seguindo o referencial de Minayo. A pesquisa foi aprovada no Comitê de Ética e Pesquisa (CAAE 31201420.6.0000.5243). Resultados: As 5 categorias criadas foram: política e relações sociais, subjetividade, comunicação e ciência, processo de trabalho e sistema único de saúde. Identificou-se que o aumento da desinformação sobre a COVID-19 levou a dificuldades na gestão de pacientes e familiares, aumento da carga de trabalho e sofrimento emocional entre os profissionais de saúde, além de afetar relacionamentos fora do trabalho e influenciar a aceitação de medidas como vacinação e distanciamento social. Percebeu-se que a desordem informacional dificultou a adesão à prática baseada em evidências, sendo apontado pelos profissionais as questões políticas como uma das principais barreiras. Conclusão: Este estudo, que segue em andamento, pretendeu compreender a influência que a desordem informacional sobretudo sobre a COVID-19 tinham no processo de trabalho dos profissionais de saúde tendo como premissa a prática baseada em evidências e tem conseguindo compreender um pouco sob a visão desses profissionais, suas principais dificuldades e barreiras, sobretudo no contexto pandêmico.
Uso de cola no reparo de traumas perineais no parto normal: revisão integrativa
Authors:   Universidade Estadual Paulista, Jesus Ariane Silva de , Ferrari Anna Paula ,   Universidade Estadual Paulista
Published: February 2024

Introdução: O trauma perineal no parto vaginal afeta a maioria das mulheres no mundo. O método mais tradicional para o reparo tecidual nestes casos é a sutura com fios, mas atualmente o uso de cola tem sido uma alternativa que tem se mostrado segura e rápida às suturas tradicionais. Objetivos: Analisar, na literatura nacional e internacional, vantagens e desvantagens do uso de cola/adesivo cirúrgico no reparo de trauma perineal no parto normal. Método: Trata-se de uma revisão integrativa de literatura, cuja busca foi realizada no dia 07 de janeiro de 2023, nas bases de dados Web of Science, na Medline, via PubMed, Cumulative Index to Nursing and Allied Healthe (CINAHL), na biblioteca virtual Scientific Electronic Library Online (SciELO) e no portal da Biblioteca Virtual de Saúde (BVS), a partir da seguinte pergunta norteadora baseada na estratégia PICO: Quais são as consequências do uso de cola/adesivo cirúrgico para reparo pós trauma perineal no parto normal? Resultados: Nove estudos primários publicados de 2002 a 2021, nos idiomas inglês e português, foram incluídos na amostra final e identificados quatro categorias temáticas: Aspectos funcionais; Aspectos técnicos; Aspectos estéticos e Satisfação com o método. Conclusão: Foram observadas como principais vantagens a diminuição no tempo do reparo perineal, o aumento da satisfação das mulheres atendidas, assim como diminuição do relato de dor. O custo elevado das colas, impossibilidade de aplicá-la em casos de sangramento excessivo e maior taxa de deiscência foram as desvantagens encontradas da cola em relação ao fio de sutura.
O brincar de crianças hospitalizadas em situação de vulnerabilidade social : perspectiva de familiares
Authors:   Universidade Estadual de Campinas, Melo Luciana de Lione , Kneip Thalyta Carvalho Pinheiro ,   Universidade Estadual de Campinas, Silva Camila Cazissi da ,   Universidade Estadual de Campinas, Maia Edmara Bazoni Soares ,   Universidade Federal de São Paulo, Cordeiro Samara Macedo ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O brincar é um direito da criança, assegurado pela Constituição Federal, pela Convenção dos Direitos da Criança e pelo Estatuto da Criança e do Adolescente. Apesar disso, não são todas as crianças que têm acesso ao brincar. A falta de acesso pode se dar em função de vulnerabilidades sociais, tais como acesso limitado a recursos, sejam eles materiais, emocionais, culturais e/ou simbólicos, o que, possivelmente, gera diversas situações prejudiciais ao desenvolvimento da criança. Objetivo: Compreender o brincar de crianças hospitalizadas em vulnerabilidade social, na perspectiva da família. Métodos: Trata-se um estudo qualitativo fenomenológico à luz do referencial teórico de Piaget, realizado em um hospital público do interior do estado de São Paulo, a partir de entrevistas com 12 famílias de crianças hospitalizadas, que atingiram o score mínimo em instrumento de estratificação de risco familiar. O acesso às famílias deu-se após a aprovação do Comitê de Ética CAAE: 47886421.3.0000.5404 Resultados: Emergiram três categorias temáticas que foram organizadas considerando o sistema ESAR para classificação de materiais lúdicos: atividades lúdicas, habilidades funcionais e atividades sociais. Os discursos das famílias evidenciaram que o brincar das crianças respeitou os estágios do desenvolvimento sensório-motor e pré-operacional e que os riscos social e de saúde não foram empecilhos para o brincar, embora a família seja apenas observadora. Considerações finais: Embora as participantes tenham discorrido sobre o brincar de seus filhos, não o fizeram de modo detalhado, inclusive demonstrando o quanto o brincar é exclusivo das crianças e, não dos adultos, que por vezes, explicitaram não acompanharem as crianças durante as brincadeiras, nem mesmo observando-as. É preciso realizar educação em saúde durante as consultas de enfermagem, para informar às famílias, desde o pré-natal, sobre a importância do brincar para o desenvolvimento saudável das crianças.
Photovoice: o uso da fotografia em pesquisa e intervenção com adolescentes com histórico de autolesão
Authors:   Universidade Federal de São Carlos, Pacheco Ingrid , Costa Luiza Cesar Riani ,   Universidade Federal de São Carlos, Gabriel Isabela Martins ,   Universidade Federal de São Carlos, Gonçalves Marilia ,   Universidade Federal de São Carlos, Carlos Diene Monique ,   Universidade Federal de São Carlos
Published: February 2024

Introdução: A literatura, assim como as experiências práticas, recomenda a utilização de estratégias metodológicas cuidadosas e éticas para aproximação de questões de sofrimento psíquico nas adolescências, tais como a autolesão não suicida. Objetivo: Relatar a experiência do uso do photovoice em pesquisa qualitativa junto a adolescentes com histórico de autolesão não suicida. Metodologia: Relato de experiência de pesquisa realizada em 2021 no interior do Estado de São Paulo com nove adolescentes do sexo biológico e gênero feminino, com idades entre 12 e 17 anos, com histórico de autolesão (CAAE 37968120.9.0000.5504). Resultados: A metodologia utilizada na pesquisa foi o photovoice: trata-se de um convite às participantes para exporem seus pontos de vista por meio de fotografias. Neste trabalho, as adolescentes foram convidadas a fotografar cenas que respondiam à pergunta: “O que alivia a minha dor?”. Cada adolescente participou de no mínimo três encontros individuais; o primeiro para aproximação, coleta de dados sociodemográficos e instrução sobre a metodologia; o segundo para apresentação das fotografias e entrevista semiestruturada; o terceiro para devolutiva e elaboração de uma cartilha para divulgação científica. Nos casos em que pesquisadora e participante consideraram adequado, foram realizados mais encontros para acolhimento. As adolescentes apresentavam suas fotografias apresentando seus significados e histórias, relatando como estes elementos as afetavam. O photovoice permitiu visualizar as percepções das participantes acerca de suas realidades cotidianas, sendo um mecanismo de ver, compreender e discutir as suas vivências, identificando o que têm carregado significado para estas adolescentes no enfrentamento à autolesão. Conclusão: O uso desta estratégia foi importante tanto como coleta de dados quanto como intervenção terapêutica e artística na identificação de elementos cotidianos de promoção de saúde mental. Foi uma metodologia bem aceita pelas participantes, que se manifestaram positivamente quanto à participação na pesquisa, aos resultados obtidos e às reflexões possibilitadas pelo percurso.
Hidrogel de insulina : avaliação in vitro e in vivo na cicatrização de feridas de camundongos hiperglicêmicos
Authors:   Universidade Estadual de Campinas, Zanchetta Flávia Cristina , Prado Thais Paulino do ,   Universidade Estadual de Campinas, Aguiar Joseane Morari Ricciardi de ,   Universidade Estadual de Campinas, Barbieri Beatriz ,   Universidade Estadual de Campinas, Araújo Eliana Pereira ,   Universidade Estadual de Campinas, Fardim Pedro ,   Katholieke Universiteit Leuven, Lima Maria Helena Melo ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O efeito que a insulina tópica tem na cicatrização de feridas em pacientes diabéticos tem sido estudado há muitos anos. No entanto, ela é uma molécula instável e facilmente degradável. Por isso, novas formulações têm sido desenvolvidas a fim de manter sua estabilidade e bioatividade. Objetivo: Avaliar os efeitos do hidrogel de insulina in vitro e in vivo em de feridas de camundongos hiperglicêmicos. Método: Estudo aprovado pelo Comitê de Ética em Pesquisa Animal da UNICAMP (5695-1). Avaliou-se a viabilidade e proliferação celular de queratinócitos (HaCaT) por meio do ensaio MTT in vitro. In vivo, após indução de Diabetes Mellitus em camundongos, ferida de 1cm² na região dorsal dos animais foram confeccionadas e randomizados em 3 grupos: Salina (SAL), Hidrogel Placebo (PLA), e Hidrogel Insulina (INS). Fotografias da ferida foram tiradas nos dias 0, 3, 7, 10, 14, 17 e 20 após a cirurgia e mediu-se sua contração. Extraíram-se tecidos no 7°, 14° e 20° dias pós-ferida para análise por meio da coloração de Hematoxilina/Eosina. Resultados: O MTT evidenciou que o hidrogel de insulina não é citotóxico para HaCat e aumentou a viabilidade celular em 31,9%. In vivo, o grupo INS apresentou maior retração da ferida nos dias 3, 7 e 10 em relação ao grupo SAL; e nos dias 7 e 10 em comparação ao grupo PLA. A análise histológica demonstrou que no 7º dia pós-ferida, o grupo INS apresentou menor inflamação e tecido mais organizado. No 14º dia pós-ferida, observaram-se características teciduais semelhantes nos três grupos. No 20º dia, houve reepitelização completa nos três grupos, porém houve menor área cicatricial no grupo INS com crescimento de anexos cutâneos. Conclusão: O hidrogel de insulina possui potencial para tratamento de feridas, já que demonstrou não ser citotóxico e contribuir com fechamento mais rápido das feridas quando comparado aos demais grupos.
Neuroplasticity – historical and contemporary perspective from a philosophical, psychological, biological, and clinical perspective
Authors: Bagrowski Bartosz
Published: February 2024

Neuroplastyczność stanowi biologiczne podłoże pamięci oraz procesów uczenia się, jednak nadal nie została w pełni poznana. Początki filozoficzno-naukowego rozważania na temat fizycznych zmian w układzie nerwowym wskutek uczenia się sięgają aż do starożytności. Wiele z dawnych koncepcji znajduje swoje odzwierciedlenie w aktualnych teoriach naukowych, np. w neuropsychologii. Choć początkowo koncepcje te miały charakter teoretyczny i funkcjonalny (np. filozoficzne ujęcie śladu pamięciowego), to jednak współczesne wyjaśnienia korzystają głównie z aparatu pojęciowego biologii molekularnej.
Does user-generated content trigger university graduates’ online purchase intention? Mediating role of brand image
Authors: Islam Md. Ashraful , Kaium Md. Abdul , Zahan Ishrat , Rahman Md. Shahinur
Published: February 2024

Academic interest in understanding the impact of user-generated content (UGC) on consumer behavior in digital marketing has grown exponentially. However, we know little about the effect of UGC on customers’ online purchase intention from developing country aspects. This underpins the current study to examine the impact of UGC on the purchase intentions of university graduates in Bangladesh. With a convenient sampling approach, a structured questionnaire was provided directly to 400 respondents; 275 usable and complete responses were extracted for data analysis. Data were empirically validated using principal component analysis, reliability test, correlation, and Hayes PROCESS macro for regression and simple mediation analysis. The findings revealed that bloggers’ recommendations, online communities, and social media content positively and significantly influence customers’ online purchase intention. Brand image also directly impacts purchase intention and mediates the relationship between bloggers’ recommendations, online community, social media content, and online purchase intention. The results of this study will facilitate policymakers and online marketers in devising UGC management policies and digital marketing strategies. The study’s results may also help online marketers, sellers, and brand representatives to understand how to enhance brand image and amplify customers’ online purchasing behavior.
Financial Performance of Dairy Cooveratives in West Java-Indonesia During the Covid-19 Pandemic and Foot-and-Mouth Disease Outbreak
Authors: Firman Dr. Achmad , Mauludin Mochamad Ali , Kusmayadi Tendy
Published: February 2024

Dairy cooperatives play an important role to collect milk production from dairy farmers, distribution of milk to the milk processing industry, concentrate supply services, credit guarantees, artificial insemination and animal health services, savings and loan services, and various other services carried out by cooperatives. This condition causes the dependence of dairy farmers on cooperatives to be quite high. External factors can influence cooperative resilience, such as the Covid-19 pandemic and Foot-and-Mouth Disease (FMD). Therefore, the purpose of this study was to analyze the performance of cooperative milk production, and to the financial performance of cooperatives in the post-pandem Covid-19 period and during FMD. The method used in this study was a survey method to KPBS Pangalengan which represents large cooperatives, KSU Tandangsari which represents medium-sized cooperatives, and KPS Bogor which represents small cooperatives. The analysis method used standard cooperative performance methods through regulations of the Deputy for Supervision of the Ministry of Cooperatives and Small and Medium Enterprises (KUKM) of the Republic of Indonesia Number 06/Per/Dep.6/IV/2016 and key perfomance index to assess the financial performance of cooperatives. The results of the study showed that the performance of cooperative milk production decreased by 19.45% during the Covid-19 pandemic to the FMD as a result of the dairy cow mortality rate of 20.14%. The financial performance of dairy cow cooperatives was in the adequate category, both during the Covid-19 pandemic and FMD, but there was a decline in the ratio in all aspects of financial performance during the FMD. Thus, the performance of milk production and the financial performance of dairy cooperatives was better during the Covid-19 pandemic than during the FMD period. Therefore, strengthening milk production by providing new dairy cows and strengthening finances is very important
Influence of Dietary Black Cumin Meal (Nigella sativa L.) on the Performance and Body Measurements of Garut Sheep
Authors: Juandita Karina Natasya , Hernaman Iman , Alhuur Ken Ratu Gharizah , Ramdani Diky
Published: February 2024

Black cumin meal has potential as feed ingredient of sheep. This study aimed to evaluate the influence of dietary black cumin meal on the performance and body measurements of Garut sheep. The study used 28 heads of male Garut sheep aged ±10 months with an average initial body weight of 20 ± 2.34 kg/head. A completely randomized design (CRD) was used to compare the influence of 4 different levels (0%, 5%, 10%, and 15%) of black cumin meal in the diet on dry matter intake (DMI, g/head/d), average daily gain (ADG, g/head/d), feed efficiency (%), body length gain (cm), chest circumference gain (cm), and height at withers gain (cm) during 70 d feeding trial using 7 replicates. The data were statistically analyzed using a One-Way Analysis of Variance and continued with Duncan new Multiple Range Test for significant results, operated by the IBM SPSS 26 program. The results showed that DMI (P<0.05), ADG (P<0.01), and feed efficiency (P<0.05) of Garut sheep were increased for a diet containing black cumin meal compared with control. Furthermore, dietary black cumin meal enhanced body length gain (P<0.05), followed by chest circumference gain, and height at withers gain (P<0.01). Dietary black cumin meal 10% is the optimum level to increase the performance and body measurements. In conclusion, dietary black cumin meal improves the performance and body measurements of Garut sheep.
The Role of Teachers in Face-to-Face Learning After the Covid-19 Pandemic to Overcome "Learning Loss" in Elementary Schools: A Case Study at UM Blitar Laboratory Elementary School
Authors: Septa Hardhita Rizki , Rahman Fatchur , Luswandari Wulan Fatikhah , Handayanto Supriyono Koes , Kusumaningrum Shirly Rizki
Published: February 2024

This study investigates the efficacy of teachers' roles in face-to-face learning to mitigate learning loss post the COVID-19 pandemic, focusing on grade VI at an exemplary elementary school. Employing a descriptive qualitative approach with a case study method, the research involves principals, grade VI teachers, and students. Findings reveal that the teachers' effective implementation of diverse learning media tailored to student needs, consistent application of consequences and rewards, and utilization of a YouTube channel for supplementary learning materials contributed to a significant reduction in learning loss. Notably, the school achieved outstanding literacy and numeracy abilities, ranking among the top nationally. The implications underscore the importance of innovative teaching methods and technology integration in post-pandemic educational recovery efforts.
Highlights:

Effective teacher roles post-COVID: Diverse teaching media, consistent application of consequences and rewards, utilization of digital platforms like YouTube for supplemental learning.
Success factors: Adaptable teaching methods tailored to student needs, proactive use of technology, and maintaining high academic standards.
Academic achievements: Notable literacy and numeracy abilities, top-ranking nationally, and successful performance in standardized tests like OSN at the provincial level.

Keywords: teacher role, face-to-face learning, learning loss
ANÁLISE DOS PROCESSOS DE RESPONSABILIDADE CIVIL DO CIRURGIÃO-DENTISTA DO ESTADO DO PIAUÍ, BRASIL
Authors: De Moura Veras Lueny , Jacometti Victor , Alves da Silva Ricardo Henrique
Published: February 2024

O objetivo deste trabalho foi levantar e analisar os processos de responsabilidade civil envolvendo cirurgiões-dentistas do estado do Piauí, entre os anos de 2015 a 2019, a fim de verificar o número de processos instaurados e suas características. Foram encontrados (n=11) processos referentes a pessoas físicas, sendo a especialidade mais incidente a Implantodontia. Em 63% dos dados, os requeridos não possuíam especialidade registrada no Conselho Federal de Odontologia na área envolvida no litígio. Os valores indenizatórios solicitados variaram de R$ 15.000,00 a R$ 101.985,00. Não houve acionamento de seguro de responsabilidade civil nos processos encontrados. A maioria dos processos foi instaurada nos últimos dois anos e ainda está em trâmite, não permitindo a obtenção das sentenças. Conclui-se que houve um aumento do número de processos instaurados no último ano verificado, acompanhando uma realidade crescente, observada em todo o país.
Analysis of Students' Internal Learning Motivation in Biology Subjects at Madrasah Aliyah Waburense
Authors: Sari Tri Maniarta , Ernawati  , Saparuddin  , Rahmania Pamungkas
Published: February 2024

The purpose of this research is to analyze students' internal learning motivation at the  Madrasah Aliyah Waburense. The type of research in this research is descriptive quantitative. The data collection technique for this research uses a mixed questionnaire. The subjects of this research consisted of 62 students in grades XI and XII at the Madrasah Aliyah Waburense. This research instrument consists of 4 indicators with 22 statements. The results of research on students' internal learning motivation were obtained; (1) the percentage of indicators of desire and desire to succeed is 68.2%, namely the medium category (2) there are hopes and aspirations for the future, 82.02%, namely the high category (3) shows interest, 54.5%, namely the medium category ( 4) diligent in facing tasks 73.4% high category. Conclusion: Internal learning motivation for classes XI and XII at the Madrasah Aliyah Waburense produces an average percentage of 70.5% in the high category.
Contaminación ambiental en los cuerpos de agua de los humedales de la costa central Lima - Perú
Authors:   , Valdivia Correa Astrid Briggithe
Published: February 2024

Los humedales ubicados en Lima forman parte de la biodiversidad de la costa central del Perú. A pesar de sus estudios sobre diferentes temas realizados en estos ambientes, poco se conoce acerca de la situación actual de la calidad de agua de los humedales costeros. Es por ello que se planteó el objetivo de conocer los diferentes estudios que señalen la situación en la que se encuentra la calidad del recurso hídrico. Cinco humedales fueron estudiados: Pantanos de Villa, Humedales de Ventanilla, El Paraíso, Medio Mundo y Puerto Viejo. Se encontró que cada humedal presenta diferentes problemas de contaminación, lo cual tiene relación con la urbanización y actividades antrópicas de sus localidades.
Plan de negocio para la producción y comercialización de bebidas naturales a base de camu-camu y aguaymanto en Lima moderna
Authors:   , Maldonado Toribio Ofelia Brenda , Olortegui De La Cruz Eliana Jhannette , Perez Canchumanta Jhonatan Cesar , Torres Azurza Hoselyn Brillith
Published: February 2024

El presente plan de negocios tiene como alternativa invertir en néctares, para una creciente demanda de este producto, debido a la población del Perú, se encuentra creciendo y con mayor poder adquisitivo, por esto, la oportunidad de presentar una nueva oferta en el mercado es atractiva. En Lima Metropolitana se tiene registrado una población de 9.5 millones de habitantes, y el presente trabajo se enfoca a la Lima Moderna que comprende 12 distritos de Lima con una Población aproximada de 2.5 millones de habitantes que comprende aproximadamente 600,000 familias de Lima, de estos habitantes, esperamos colocar 419.499 botellas de néctar a un precio de 4 soles en el primer año. Los indicadores financieros de este proyecto de inversión en néctares de sabores que representan la cultura del país son un VANE de S/ 71,201.00 soles y una TIRE del 15%, lo cual supera al WACC- con un VANF de S/ 80,335.00 soles y una TIRF de 16 %, siendo el negocio rentable en ambos casos.
Calcium carbonate instability and graphite formation in shallow subduction zones
Authors: Liu Jin , Shen Kewei , Gui Weibin , Li Jie
Published: February 2024

Subducted carbonates dominate the global carbon fluxes from Earth's surface to its interior, hence their fate ultimately modulates the planet's long-term climate dynamics. Calcium carbonate is a major component of subducted slabs, yet little is known about its stability under relevant conditions. Here, we show that aragonite decomposes and forms graphite at 1.8-3.0 gigapascals and 230-900 °C, even under relatively oxidizing conditions. Interestingly, graphite forms exclusively from aragonite but not calcite, revealing that crystal structure influences calcium carbonate instability and graphite formation as much as oxygen fugacity. Graphite formation in the vast regions of shallow subduction zones would help retain carbon, thus facilitating its transportation to greater depths.
Understanding the Association Between Injustice Appraisals, Depression Symptoms, and Stigma in Individuals with Traumatic Spinal Cord Injury
Authors: Monden Kimberley , Peiffer Josh , Philippus Anglea , Kanaster Karen
Published: February 2024

Study Design: This is a secondary analysis of data from a cross-sectional, observational study.
Research Method/Design: A bootstrapping mediation analysis was conducted to evaluate the stigma-mediated relationship between injustice appraisals and depression symptoms. Injustice appraisals were assessed using the Injustice Experience Questionnaire, stigma with the Spinal Cord Injury Quality of Life Stigma–Short Form, and depression symptoms with the Patient Health Questionnaire–9. A sample of 225 participants completed the questionnaires; eight participants were removed due to incomplete data, resulting in a final sample size of 217 participants (79% male; 21% female).
Results: Injustice appraisals were significantly correlated with depression symptoms and time since injury. Stigma was found to mediate the relationship between injustice appraisals and depression, with an estimated proportion mediated of 80.9%
Conclusions/Implication: Consistent with previous research, injustice appraisals were associated with greater severity of depression symptoms. This study provides a novel finding that the relationship between injustice appraisals and depression symptoms is mediated by stigma. Results provide further evidence for the role of injustice appraisals after SCI and a potential mechanism (i.e., stigma) by which it may exert its effect on depression symptoms.
Research on the effect of the trajectory of the spinning tool on the shape of the product in the process of axially asymmetric spin forming
Authors: Gądek Tomasz , Majewski Marcin , Sułek Bartosz Krzysztof , Plewa Krzysztof
Published: February 2024

The method of developing the trajectory of a shaping tool in classical spinning is relatively simple and fast, and does not require complicated operations. Such a solution is facilitated by tool kinematics. Rotational forming of asymmetrical products, due to different, more sophisticated, tool kinematics, requires the generation of a very complex trajectory, which takes a long time to prepare. The paper analyzes and describes two methods for writing and generating the trajectory of the movement of a spinning tool’s roll during the shaping of axially asymmetric products. The advantages and disadvantages of each method were analyzed. The shape of the developed trajectory was compared depending on the chosen method of its generation. In addition, an experimental study was conducted to verify the correctness of the developed trajectory. The study was conducted for the 1050A aluminum alloy in delivery condition H111, for the material thicknesses of 2 mm and 2.5 mm. The limitations of the shaping of axially asymmetric products due to the shape of the template were also analyzed.
RETRACTED: Antibacterial Effects of Silver Diamine Fluoride, Potassium Iodide and Nanosilver Fluoride on Dual-species Biofilm
Authors: Karaduran Büşra , Çelik Sibel , Üçüncü Merve Yıldırım , Topçuoğlu Nursen , Gök Mehmet Koray , Koruyucu Mine
Published: February 2024

The authors have requested that this preprint be removed from Research Square.
Urban plants with different seed dispersal modes have convergent response but divergent sensitivity to climate change and anthropogenic stressors
Authors: Song Kun , Gao Zhiwen , Pan Yingji , Zhuge Mingming , Wu Tian , Xia Tiyuan , Hu Yuandong , Da Liangjun , Cieraad Ellen
Published: February 2024

Spontaneous plants are crucial components of urban biodiversity. The distribution of spontaneous plants can be profoundly affected by their seed dispersal mode and environmental factors in urban systems. Since a comprehensive investigation into the drivers of successful seed dispersal modes of spontaneous plants is still lacking, we explored the impacts of natural factors, dispersal limitation, and habitat quality factors on the diversity pattern of spontaneous plants. We assessed the diversity patterns of four seed dispersal modes in 16 major cities in Yunnan province, the most biodiverse province in China. A total of 1,744 spontaneous plants of 916 genera and 175 families were recorded in 893 green patches. The dominating seed dispersal mode of urban spontaneous plants in most cities (13 out of 16) was autochory (33.5–38.7%), with hydrochory being least frequent (4.3–10.9%). Our research highlights spontaneous plants in heavily disturbed anthropogenic ecosystems, such as urban areas, tend to adopt convergent strategies to address environmental stressors. Their richness was significantly higher in colder and humid climates. However, as dispersal limitations (measured by distance to city boundary, city size and urbanization rate) increased and decrease in habitat quality (as expressed by patch area), the richness of all dispersal modes experienced a reduction. However, the sensitivities among different dispersal modes to these factors are divergent. Hydrochory exhibited the strongest sensitivity to habitat quality and climate factors. Whereas autochory demonstrated a strongest sensitivity, and anemochory showed a weakest sensitivity to dispersal limitation. These results suggest that include improving habitat quality or creating green corridors to mitigate dispersal limitation between urban areas and surrounding mountains will be valuable additions to urban biodiversity conservation efforts.
Orally delivered biodegradable targeted inflammation resolving pectin-coated nanoparticles induce anastomotic healing post intestinal surgery
Authors: Lee Jong Hyun , Reischl Stefan , Walter Robert Leon , Vieregge Vincent , Weber Marie-Christin , Xu Runxin , Chen Hao , Kasajima Atsuko , Friess Helmut , Neumann Philipp-Alexander , Kamaly Nazila
Published: February 2024

Although medical treatment is sucessful in most cases in patients with inflammatory bowel diseases (IBD), a percentage of patients require surgical resection of diseased bowel segments at least once in their lifetime. Healing success of the intestinal anastomosis is at high risk, especially in presence of acute inflammation. Failure of anastomotic healing is a life-threatening complication and causes high socioeconomic costs. Common anti-inflammatory medications can have detrimental effects on wound healing. Thus, targeted perioperative therapeutics supporting anastomotic healing during colitis are an urgent medical need. Here, we develop a novel basal membrane targeted controlled release, pectin-coated polymeric nanoparticle (NP) encapsulating a highly potent inflammation resolving mediator, the peptide Ac2-26. These NPs can undergo gastric passage and facilitate localized release of the therapeutic peptide in the colon via degradation of their pectin-chitosan coating by microbial pectinases, which subsequently exposes a collagen IV targeted NP surface, allowing for further binding and retention of the NPs at the intestinal wound. To test these NPs, we used a murine surgical model combining the formation of an intestinal anastomosis with the induction of a preoperative colitis by dextran sodium sulfate. In this model, perioperative administration of pectin-chitosan coated NPs containing Ac2-26 (P-C-Col IV-Ac2-26-NP) led to the reduction of colitis activity in the postoperative phase. Macroscopic wound closure was improved by P-C-Col IV-Ac2-26-NP treatment as evaluated by endoscopy and intraabdominal adhesion scoring. Microscopic analysis of the healing process showed an improved semiquantitative healing score in the treatment group. In this proof-of-concept study we demonstrate that novel P-C-Col IV-Ac2-26-NP could be a promising and clinically feasible perioperative treatment strategy for IBD patients.
Long-term Outcomes After Particle Radiation Therapy in Patients with Nasopharyngeal Adenoid Cystic Carcinoma
Authors: Hu Weixu , Hu Jiyi , Huang Qingting , Gao Jing , Zhang Haojiong , Kong Lin
Published: February 2024

Background
Nasopharyngeal adenoid cystic carcinoma (NACC) a is a relatively rare salivary gland tumor and is generally associated with a poor outcome. High-dose radiotherapy is a key treatment in patients with NACC. This study reported the long-term efficacy and safety of particle beam radiation therapy (PBRT) for NACC.
Methods and materials:
Twenty-six patients with nonmetastatic NACC who received definitive PBRT alone were included in this retrospective study. The majority of patients (92.3%) had locally advanced disease. Twenty-four (96.15%) patients received intensity-modulated proton radiotherapy (IMPT) followed by a carbon ion radiotherapy (CIRT) boost, and one patient receive CIRT alone. Overall survival (OS), local control (LC), regional control (RC), and distant metastasis control (DMC) rates were calculated via the Kaplan-Meier method.
Results
The median follow-up time was 46.95 months for the entire cohort. Seven patients experienced local recurrence, and neck lymph node relapse occurred in one patient. The 3- and 4-year OS, LC, RC, and DMC rates were 100% and 91.7%, 92.3% and 84.6%, 95.8% and 87.8%, and 90.2% and 71.3%, respectively. 91.3% of the patients achieved complete remission of gross tumor at 1 year after PBRT. Severe acute toxicity was only observed in two patients. One patient with orbital apex invasion developed grade 4 visual acuity decrease. No late grade 3 or 5 toxicity was observed.
Conclusion
Definitive PBRT provided a satisfactory 4-year OS for locally advanced NACC. Toxicity was acceptable and mild. Further follow-up is necessary to confirm the efficacy and safety of definitive PBRT for patients with NACC.
Combined transcriptomic and proteomic analysis reveals the mechanism of Xing-Qi-Huo-Xue granules on BLM-induced pulmonary fibrosis in rats
Authors: Gao Jian , Yang Han , Jiang HuanYu , Hao YanWei , Li GangGang , Zhang YuWei , Hu SiYing , Su YuChen , Du QuanYu , Wang Fei
Published: February 2024

Background
Pulmonary fibrosis is a phenotype of many lung disease pathologies, characterized by alveolar structure destruction, extracellular matrix anomalous accumulation, and abnormal collagen deposition. Traditional Chinese medicine is becoming increasingly important in treating pulmonary fibrosis, and Xing-Qi-Huo-Xue (XQHX) granules have been clinically proven effective, but the underlying mechanism is unclear.
Purpose
In this experiment, The mechanism of XQHX in treating rats with PF was elucidated by combined transcriptomic and proteomic analyses.
Method
The main components of XQHX granules was detected by liquid chromatography/mass spectrometry (LC/MS) first. A bleomycin (BLM)-induced rat model was established and lung histology was assessed by hematoxylin eosin and Masson's stain. Rat lung tissues were subjected to transcriptome and proteome sequencing, and bioinformatic analyses of differential genes/proteins were performed. Collagen I/III mRNA expression levels were determined by RT-qPCR, and lung hydroxyproline (HYP) levels were determined by colorimetric assay.
Results
A total of 16 main compounds including agroastragaloside IV, astragaloside I, astragaloside II, etc. in XQHX were detected by LC/MS. XQHX significantly improved BLM-induced lung tissue structure destruction and HYP content. Furthermore, XQHX inhibited lung tissue mRNA expression of collagens I, and III. Bioinformatics analysis showed that 1657 genes and 590 proteins were differentially expressed in the normal control group (N) compared to the BLM-induced control group (P), and 2.46 g/kg XQHX- treated group (X) had 805 genes and 499 proteins differentially expressed. Then we identified that XQHX exerts an anti-fibrotic effect by regulating arginine (Arg1), which is involved in the arginine biosynthesis pathway and the arginine and proline metabolism pathway.
Conclusion
Our results suggest that XQHX reduces arginase biosynthesis by down-regulating Arg1 expression as a central mechanism and potential therapeutic approach to prevent BLM-induced pulmonary fibrosis.
Optimization of Bus Stop Location based on Spatial Analysis and K-Means Clustering Method – A Case Study in Hohhot City
Authors: Yu Jingqiao , Zhu Yuan , Wu Chaowen , Song Guoqing
Published: February 2024

The location of bus stops is crucial for attracting bus passengers. Researchers have explored various methods, such as questionnaire surveys and field investigations, to determine the location of bus stops, but these methods largely rely on experience and intuition. With the introduction of big data, a more scientific approach has emerged for siting bus stops. Based on the location data from cellular base stations in Hohhot, China, this paper uses K-means clustering and spatial analysis to calculate the coordinates of bus stops within 4 kilometers of the central business district (CBD) area. Then the study utilizes the city point of interest (POI) data to compare the new bus stops and existing ones in terms of the POI number, bus stop spacing, and POI average distance. The study concludes that the new bus stops outperform the existing ones in terms of POI number and stops spacing. The Analytic Hierarchy Process (AHP) is applied to evaluate the results that indicate the newly constructed bus stops are superior to the existing ones, with an overall optimization rate of 3.194%.The findings of this study can serve as decision-making references for urban planning departments and public transportation operators, aiming to increase public transport passenger flow and improve the traffic conditions in cities. Additionally, the methods utilized in this research can be applied to other cities, assisting them in site selection of bus stops and optimal planning, thereby promoting the development of public transportation.
Imaging characteristics of hypervascular focal nodular hyperplasia-like lesions in chronic alcoholic liver disease
Authors: Urase Atsushi , Tsurusaki Masakatsu , Kozuki Ryohei , Kotera Taku , Kono Atsushi , Sofue Keitaro , Ishii Kazunari
Published: February 2024

Purpose
We evaluated diagnostically differential radiological findings between focal nodular hyperplasia (FNH)-like lesions and hepatocellular carcinoma (HCC).
Materials and Methods
We studied pathologically confirmed FNH-like lesions in 13 alcoholic-cirrhosis patients who were negative for hepatitis-B surface antigen and hepatitis-C virus antibody and underwent dynamic computed tomography (CT) and magnetic resonance imaging (MRI), including superparamagnetic iron oxide (SPIO) and/or gadoxetic acid-enhanced MRI. Seven patients underwent angiography-assisted CT. Evaluated lesion features included arterial enhancement pattern, washout appearance (low density compared to surrounding liver parenchyma), signal intensity on T1-weighted image (T1WI) and T2-weighted image (T2WI), central scar presence, chemical shift on in- and out-of-phase images, and uptake pattern on gadoxetic acid-enhanced MRI hepatobiliary phase and on SPIO-enhanced MRI.
Results
Eleven patients had multiple small lesions (< 1.5 cm). Radiological features of FNH-like lesions included hypervascularity despite small lesion, lack of “corona-like” enhancement in the late phase on CT during hepatic angiography (CTHA), high-intensity on T1WI, slightly high- or iso-intensity on T2WI, no signal decrease in out-of-phase images, and complete SPIO uptake or incomplete/partial uptake of gadoxetic acid. Pathologically, like HCC, FNH-like lesions showed many unpaired arteries and sinusoidal capillarization, similar to those in HCC.
Conclusion
FNH-like lesions have unique radiological findings useful for differential diagnosis. Specifically, SPIO- and/or gadoxetic acid-enhanced MRI and CTHA features might facilitate differential diagnosis of FNH-like lesions and HCC.