bluuebunny/crossref_metadata_2025 huggingface dataset:
Uncertainty-bounded estimates of ash cloud properties using the ORAC algorithm: Application to the 2019 Raikoke eruption
Authors: Prata Andrew T. , Grainger Roy G. , Taylor Isabelle A. , Povey Adam C. , Proud Simon R. , Poulsen Caroline A.
Published: June 2022

Abstract. Uncertainty-bounded satellite retrievals of volcanic ash cloud properties such as ash cloud-top height, effective radius, optical depth and mass loading are needed for the robust quantitative assessment required to warn aviation of potential hazards. Moreover, there is an imperative to improve quantitative ash cloud estimation due to the planned move towards quantitative ash concentration forecasts by the Volcanic Ash Advisory Centers. Here we apply the Optimal Retrieval of Aerosol and Cloud (ORAC) algorithm to Advanced Himawari Imager (AHI) measurements of the ash clouds produced by the June 2019 Raikoke (Russia) eruption. The ORAC algorithm uses optimal estimation to consolidate a priori information, satellite measurements and associated uncertainties into uncertainty-bounded estimates of the desired state variables. Using ORAC, we demonstrate several improvements in thermal infrared volcanic ash retrievals applied to broadband imagers. These include: an improved treatment of measurement noise, accounting for multi-layer cloud scenarios, distinguishing between heights in the troposphere and stratosphere, and the retrieval of a wider range of effective radii sizes than existing techniques by exploiting information from the 10.4 μm channel. Our results indicate that 0.73 ± 0.40 Tg of very fine ash (≤ 15 μm, radius) was injected into the troposphere and stratosphere during the main eruptive period from 21 June 18:00 UTC to 22 June 10:00 UTC. The total mass of very fine ash decreased from 0.73 Tg to 0.10 Tg over ~48 h with an e-folding time of 20 h. We also estimate a distal fine ash mass fraction of 0.47 ± 0.3 % based on the total mass of very fine ash retrieved and the ORAC-derived height time-series. Several distinct ash layers were revealed by the ORAC height retrievals. Generally, ash in the troposphere was composed of larger particles than ash present in the stratosphere. We also find that our implementation of the ORAC algorithm was reliable out to four days and was able to track the median ash cloud at concentrations below peak ash concentration safety limits (< 4 mg m-3) if typical ash cloud geometric thicknesses were assumed. The ORAC height retrievals for the Raikoke case study have a bias and precision of -2.22 km and 2.85 km, respectively, based on comparisons with CALIOP and GOES-17 height validation data. The dataset generated here provides uncertainties at the pixel level for all retrieved variables and could potentially be used for dispersion model validation or implemented in data assimilation schemes. Future work should focus on improving ash detection, improving height estimation in the stratosphere and exploring the added benefit of visible channels for retrieving effective radius and optical depth in opaque regions of nascent ash plumes.
Technical note: Graph-theory-based heuristics to aid in the implementation of optimized drinking water network sectorization
Authors: Rokstad Marius Møller , van Laarhoven Karel
Published: June 2022

Abstract. Drinking water distribution networks form an essential part of modern-day critical infrastructure. Sectorizing a network into district metered areas is a key technique for pressure management and water loss reduction. Sectorizing an existing network from scratch is, however, an exceedingly complex design task that designs in a well-studied general mathematical problem. Numerical optimization techniques such as evolutionary algorithms can be used to search for near-optimal solutions to such problems, but doing so within a reasonable time frame remains an ongoing challenge. In this work, we introduce two heuristic tricks that use information of the network structure and information of the operational requirements of the drinking water distribution network to modify the basic evolutionary algorithm used to solve the general problem. These techniques not only reduce the time required to find good solutions but also ensure that these solutions better match the requirements of drinking water practice. Both techniques were demonstrated by applying them in the sectorization of the actual distribution network of a large city.
Linking reported drought impacts with drought indices, water scarcity, and aridity: the case of Kenya
Authors: Lam Marleen R. , Matanó Alessia , Van Loon Anne F. , Odongo Rhoda , Teklesadik Aklilu D. , Wamucii Charles N. , van den Homberg Marc J. C. , Waruru Shamton , Teuling Adriaan J.
Published: June 2022

Abstract. The relation between drought severity, as expressed through widely used drought indices, and drought impacts is complex. In particular in water-limited regions where water scarcity is prevalent, the attribution of drought impacts is difficult. This study assesses the relation between reported drought impacts, drought indices, water scarcity, and aridity across several counties in Kenya. The monthly bulletins of the National Drought Management Authority in Kenya have been used to gather drought impact data. A Random Forest (RF) model was used to explore which set of drought indices best explains drought impacts on: pasture, livestock deaths, milk production, crop losses, food insecurity, trekking distance for water, and malnutrition. The findings of this study suggest a relation between drought severity and the frequency of drought impacts, whereby the latter also showed a relation with aridity, whilst water scarcity did not. The results of the RF model reveal that drought impacts can be explained by a range of drought indices across regions with different aridity. While the findings strongly depend on the availability of drought impact data and the socio-economic circumstances within a region, this study highlights the potential of linking drought indices with text-based impact reports. In doing so, however, spatial differences in aridity and water scarcity conditions have to be taken into account.
Apresentação Auto-Imune Rhupus Like de cancer de pulmão de não pequenas células
Authors: Barbosa Filho Ricardo , Menezes Tatiane Bastos Mangueira de , Dias Pérola Reis de Souza , Silva Emanuelly Thays Muniz Figueiredo , Lustosa Kristopherson , Costa Fabrício André Martins da
Published: June 2022

Rhupus, ou Síndrome Rhupus, é uma doença reumatológica rara caracterizada pela sobreposição de Lúpus Eritematoso Sistêmico e Artrite Reumatóide em pacientes preenchendo critérios de SLICC e ACR/EULAR. Objetivo: Descrever o caso clínico de uma paciente com câncer de pulmão de não pequenas células apresentando quadro clínico compatível com Síndrome Rhupus e realizar revisão bibliográfica sobre Rhupus e sua clínica. Metodologia: Estudo do tipo relato de caso, descritivo, qualitativo com informações obtidas diretamente dos registros médicos realizados durante a internação hospitalar. Discussão: Síndrome Rhupus, caracterizada pela sobreposição de LES e AR, possui duas apresentações mais comuns, a primeira são pacientes que iniciam quadro de AR, e, após, são diagnosticados com LES, compreendendo 2/3 dos casos de Rhupus. A segunda apresentação consiste em pacientes inicialmente com LES ou apresentam as duas doenças diagnosticadas no início do quadro. Tratando-se de uma síndrome rara, não existem critérios diagnósticos validados para esta enfermidade. Conclusão: Embora não rara a interposição de doenças reumatológicas, Rhupus possui prevalência estimada em 0,09% da população. O diagnóstico pode ser dificultado por não existirem critérios diagnósticos bem definidos e pela raridade, porém este diagnóstico pode ser determinante para a abordagem adequada do paciente e melhor prognóstico, reduzindo complicações relacionadas a LES e/ou AR.
Mortalidade de mulheres: um panorama da morte violenta na capital do estado de Rondônia no período de 2013 a 2018
Authors: Gutzeit Ennely Mendonça , Sobral Lucas Levi Gonçalves , Batista Maxwendell Gomes , Campos Silvecler Cortijo de , Cortijo Nicoli Brandalise Stubs , Lopes Thiago Vaz , Silva Brenda Karoliny Souza da , Barreto Cristófer Castelo Branco , Miranda Gabriel Rubens Bernardo , Lopes Iara Vaz , Claros Ramon Rosario , Pacini Yasmin Silvino
Published: June 2022

Entre os anos de 2013 a 2017 no Brasil, segundo o apresentado pelo Sistema de Informações sobre Mortalidade – SIM, foram registrados 137.624 óbitos de mulheres, vítimas de morte violenta, dos quais 1145 (0,83%) ocorreram no estado de Rondônia. Diante da importância social e epidemiológica destes dados, fez-se necessário analisar a causa dos óbitos computados no estado de Rondônia, quanto ao perfil epidemiológico das mulheres de Porto Velho-RO, tendo como indicadores idade, raça e instrumento ou meio utilizado para violentá-las. As informações foram obtidas através da análise do banco de dados do Instituto Médico Legal, em Porto Velho – Rondônia, no período de 2013 a 2018, tendo como critério de inclusão as de mortes violentas de mulheres. Este estudo epidemiológico pioneiro para o estado de Rondônia apresentou dados estatísticos fundamentais que subsidiarão políticas públicas para prevenção da morte violenta de mulheres.
ÜÇÜNCÜ KİŞİNİN GERÇEĞE AYKIRI İTİRAZDA BULUNMASI NEDENİYLE İCRA VE İFLÂS KANUNU’NUN 89/4 HÜKMÜ UYARINCA AÇILACAK TAZMİNAT DAVASININ BELİRSİZ ALACAK DAVASI ŞEKLİNDE AÇILIP AÇILAMAYACAĞI ÜZERİNE BİR DEĞERLENDİRME
Authors: DIRENİSA Efe
Published: June 2022

Üçüncü kişi kendisine tebliğ edilen haciz ihbarnamesine karşı gerçeğe aykırı şekilde itiraz ederse, İcra ve İflâs Kanunu’nun 89. maddesinin dördüncü fıkrası uyarınca takip alacaklısının itirazın aksini ispat etmek suretiyle üçüncü kişiden tazminat talep etmesi mümkündür. Uygulamada üçüncü kişinin haciz ihbarnamesine gerçeğe aykırı itirazda bulunması durumunda, takip alacaklısının açtığı tazminat davasında talep edeceği tazminat miktarını belirlemesi büyük zorluğa neden olmaktadır. Takip alacaklısı, üçüncü kişi ile takip borçlusu arasındaki hukukî ilişkiye yabancıdır. Üçüncü kişinin takip borçlusuna olan borcu, taraflar arasındaki bir sözleşmeden doğmuşsa, takip alacaklısının sözleşmenin ayrıntılarını bilmesi veya sözleşmeye müdahale etmesi mümkün değildir. Alacaklı davacının, davanın açılması anında alacak miktarını belirlemesinin mümkün olmadığı veya söz konusu belirlemeyi yapmasının kendisinden beklenemeyeceği durumlarda Hukuk Muhakemeleri Kanunu’nun 107. maddesi uyarınca davanın belirsiz alacak davası olarak açılması mümkün kılınmıştır. Bu çalışmada, İcra ve İflâs Kanunu’nun 89. maddesinin dördüncü fıkrasında öngörülen tazminat davasının hangi durumlarda belirsiz alacak davası olarak açılabileceği incelenecektir.
MEMBANGUN KESADARAN INVESTASI MELALUI SEKOLAH PASAR MODAL
Authors: Kusnindar Arum Arupi , . Wagiyo , Prastiyo Yogi
Published: June 2022

Investasi merupakan salah satu pendorong utama pertumbuhan ekonomi suatu negara. Investasi saat ini dapat dilakukan dengan mudah melalui pasar modal. Literasi keuangan dan investasi sangat penting karena semakin tinggi literasi keuangan dan imvestasi semakin tinggi motivasi melakukan investasi di pasar modal. Oleh karena itu kegiatan pengabdian ini dilakukan untuk memberikan pengetahuan dan ketrampilan mengenai investasi di pasar modal. Kegiatan pengabdian dilakukan dengan metode seminar dan pelatihan yang di berikan oleh dua orang dosen dan bekerja sama dengan Bursa Efek Indonesia Cabang Lampung. Materi yang diberikan terkait profil BEI serla lembaga lain yang terkait dengan Pasar Modal, mekanisme pasar modal, jenis – jenis investasi yang bisa di pilih, resiko yang harus di pertimbangkan serta keuntungan yang bisa didapatkan dari investasi melalui pasar modal. Dalam kegiatan pelatihan materi yang diberikan terkait dengan pengenalan berbagai lembaga sekuritas, simulasi menggunakan berbagai aplikasi yang ada serta tips dan trik bagaimana melakukan investasi di pasar modal agar mendapatkan keuntungan.Hasil dari kegiatan pengabdian ini adalah meningkatnya pengetahuan dan ketrampilan peserta mengenai pasar modal dan mempunyai ketrampilan dalam menggunakan berbagai aplikasi dari beberaap lembaga sekuritas legal.
«Խորհրդավոր ընթրիքը» 17-19-րդ. դդ. հայկական սրբապատկերներում
Authors: Դադայան Թամարա
Published: June 2022

17-19-րդ դդ. հայկական հաստոցային կերպարվեստում ուրույն տեղ են զբաղեցնում սրբապատկերները: Հաճախ մեզ հասած գործերում անհայտ է և նկարիչը, և պատկերման վայրը, և պատվիրատուն: Թվացյալ այդ խառնաշփոթում, դրանք ունեն հստակ պատկերագրական, հորինվածքային, և գունային դրսևորումներ: Այդ սրբապատկերներից մի քանիսը ներկայացնում են եվրոպական պատկերագրական տիպը, իսկ մյուսները հայկական կանոնը: Գրեթե բոլոր սրբապատկերներում առկա է մոնումենտալ մտածելակերպը: Խնդրո առարկա թեմայի շրջանակում կդիտարկենք Հայաստանի պետական պատկերասրահում պահվող մի քանի օրինակներ:
Եղեգնամոր (Չանգյի) եկեղեցին IX-XI դդ. Տայք-Գուգարքի միջնադարյան հայկական ճարտարապետական դպրոցի համատեքստում
Authors: Նահատակյան Դավիթ , Ակոպով Արկադի , Գրիգորյան Անի
Published: June 2022

Հոդվածում քննարկվում է Զարգացած միջնադարի հայկական ճարտարապետության մի հետաքրքիր կառույց, որը հենվելով վաղքրիստոնեական հայկական ճարտարապետության արդեն հայտնի ձեռքբերումների և իր դարի ոճական նորարարությունների վրա առաջ է բերել մի հետաքրքիր սինթեզ, ինչը կարիք ունի առանձնահատուկ հետազոտման: Պաշտամունքային կառույցի հիմնական ճարտարապետական կերպարը բացահայտելու և իրատեսական վերլուծություններ կատարելու համար այն դիտարկվել է Տայք-Գուգարքի հայկական միջնադարյան ճարտարապետական դպրոցի համատեքստում:
Relationship of Anti-Mullerian Hormone in Polycystic Ovary Syndrome Patients with Different Subgroups
Authors: Farooq Sumaiya , Baloch Sanobar , Awan Shazia , nissa Fakharu
Published: June 2022

Objective: To determine the association between hyperandrogenism (HA) and polycystic ovarian morphology in a Chinese cohort of patients with polycystic ovary syndrome and the usefulness of anti-Mullerian hormone Methods: Patients who visited the Department of Obstetrics and Gynecology at Indus Medical College Tando Muhammad Khan between May 2020 and October 2020 were the subjects of a prospective case-control study. According to Rotterdam criteria, 50 females with Polycystic ovary syndrome (PCOS) and 50 females without the condition participated in the study. Results: An teenage patient clinic at our hospital enrolled 100 consecutive patients (50 by PCOS, 50 by healthy controls aged equal to the adolescent patients). Menstrual anomaly and hirsutism were most common in the study group, while vaginal discharge was most common in the control group. Analyses of anthropometric measures between the two groups showed a significant difference (p<0.05). In the PCOS group, both plasma fasting insulin (p-value = 0.001) and HOMA index (p value =0.003) had statistically greater values. PCOS patients also had significantly higher means of fT and 17-OH-P, as well as LH and LH/FSH ratios. Serum AMH levels were found to be negatively correlated with FSH levels in all patients (r=-0.238, p=0.031). The AUC value indicated by ROC analysis for distinguishing PCOS was 0.678. However, the sensitivity and specificity scores according to the highest Youden index were 47.8% and 76.1%, respectively. Conclusion: The Anti-Mullerian hormone level is also linked to the existence of polycystic ovary morphology, which suggests that the AMH level might have a role in the diagnosis and treatment of PCOS. Keywords: Anti-Mullerian Hormone, Polycystic Ovary Syndrome, Polycystic Ovary Morphology
The New Paradigm in Medicine
Authors:   Bulgarian Academy of Sciences, Vasseva-Dikova Julia
Published: June 2022

From the antiquity to nowadays the connection between philosophy and medicine is of substantive importance. One of the outstanding figures for medicine as Hippocrates of Kos, named “the father of medicine”, built the fundamental principals of medicine as rational endeavour. The other important figure in late antiquity – Claudius Galenus or Galen of Pergamon –made an important thesis that a good doctor is a philosopher too (work That the Best Physician is also a Philosopher). This work analyses the questions concerning contemporary relationships between philosophy and medicine today. One of the central topics is focused on contemporary criteria for medical theory, research and practice. In the beginning of the 90s, the so-called Evidence-Based Medicine (EBM) formulated specific methodological features that medicine has to aspire to. Today, every field of medicine is based on the principles formulated by EBM. This gives grounds for a number of authors to talk about a "new paradigm" in medical science and practice and to base this idea on the EBM movement. The present paper will analyse the discussion of whether EBM is a paradigm according to Kuhn’s idea of a “paradigm shift”, and will critically analyse scientific change situation in the context of modern medicine (scientific and social aspects).
Creative Motivation and Flourishing – Psychological and Social Aspects
Authors:   Paisii Hilendarski University of Plovdiv, Tagareva Kirilka , Gereva Magdalena ,   Paisii Hilendarski University of Plovdiv
Published: June 2022

Creative motivation is considered in the context of personality structure and flourishing as an indicator of positive development. The aim of the present study is to explore the relationships in the field of creativity and creative motivation as factors for achieving psychological well-being and flourishing, as well as their presence within various psychological profiles. Hypotheses have been raised in order to measure the presence of creativity indicators within certain psychological types in relation to the level of creative motivation and flourishing. The survey instruments used are: Myers Briggs Type Indicator, Torrance Creative motivation scale and Diener Flourishing Scale. The results presented are based on a pilot study conducted in Plovdiv. The sample includes people in early adulthood, authentic folklore dance performers.
Study of LIF polymorphisms and phenotypes of CAKUT in a Brazilian pediatric population
Authors: Gouveia Kerlane , Silva Cláudia
Published: June 2022

The congenital anomalies of the urinary tract — CAKUT emerge from the interaction between genetic anomalies and environmental factors present before and during pregnancy. The aim of this study was to evaluate possible associations between pathways of gene polymorphism LIF and CAKUT. The study was done with 538 Brazilian volunteers, the control group being 160 females and 102 males, totaling 262 healthy individuals. The case group contained 115 females and 161 males, totaling 276 pediatric patients originated from the CAKUT ambulatory from Federal University of Minas Gerais, Brazil. The rs 737812, 929271 and 737921 of LIF were investigated. In association analyzes between cases and controls, no correlation was seen between the rs 737812 and 929271 of LIF and CAKUT. There was a positive association between rs 737921 and general CAKUT as well as with the various phenotypes studied except of hydronephrosis and of multicystic renal dysplasia. Force of association of rs LIF to general CAKUT is measured by a p-value of 0.0009 after 1000 permutations.
Extração e caracterização de espécie do gênero opuntia para aplicação como biocoagulante e biofloculante no processo de tratamento de águas e efluentes
Authors: Braga Costa Santos Eduardo , Dantas Muniz Alves Letícia , Dantas Muniz Denise , Perazzo Barbosa Normando , Amaro Santos Correia Edvaldo , Viana da Silva Márcia
Published: June 2022

O uso de coagulantes inorgânicos no tratamento de efluentes tem gerado discussões sobre os limites de eficiência e os efeitos colaterais no corpo humano, buscando-se alternativas que desempenhem o tratamento com o impacto ambiental minimizado. O estudo objetiva avaliar a efetividade da palma orelha de elefante mexicana (Opuntia stricta haw) cultivada no estado da Paraíba no tratamento de águas e efluentes e seu potencial técnico como biocoagulante e biofloculante. Caracterizações de espectrofotometria no infravermelho – FTIR, análise termogravimétrica – TGA, difratometria de raios-x – DRX, teste de sólidos suspensos, níveis de turbidez e pH foram realizados. Os resultados obtidos indicaram que a espécie estudada reduziu a turbidez das amostras de efluentes em um percentual superior a 75% e a quantidade removida de sólidos suspensos é equivalente, além da detecção de componentes minerais nas amostras da palma estudada, que levanta a hipótese de atuar no equilíbrio dos níveis de pH, porém de forma limitada.
Banco de sementes de áreas submetidas ao pastejo de caprinos e ovinos no sertão paraibano
Authors: Pessoa Rosa Maria dos Santos , Silva Divan Soares da , Bakke Ivonete Alves , Pereira Filho José Morais , Pereira Fernando Emanoel Messias , Dutra Júnior Marcelo Pereira
Published: June 2022

Os estudos do banco de sementes na Caatinga permitem avaliar os impactos dos animais e caracterizar os estratos presentes no ambiente. O trabalho teve por objetivo verificar a densidade, composição e diversidade do banco de sementes em áreas submetidas ao pastejo caprino e ovino. Para isso, foram selecionadas quatro áreas localizadas na Fazenda Lameirão, no município de Santa Teresinha – PB. Em dezembro de 2014, 80 amostras de solo mais serapilheira na profundidade de 0-5 cm foram coletadas em cinco parcelas/área (10 m x 10 m). Durante o período de um ano foram quantificadas e identificadas indivíduos do banco de sementes há nível de família, gênero, espécie e hábito de vida, além de riqueza, abundância e equabilidade. As áreas que detiveram as maiores concentração de indivíduos foram as áreas quatro e um com 453 e 442 indivíduos respectivamente. Os maiores valores de diversidade e equabilidade de espécies foram para áreas quatro (H’=2,34 e e’=0,68), seguida pela área três (H’=2,09 e e’=0,59). O banco de semente das áreas de pastagens são compostos por herbáceas, em especial a Hyptis suaveolens. A degradação, associa-se à ausência da indivíduos arbóreos indica efeito negativo do pastejo à germinação de sementes.
Empreendedorismo e riscos da criminalidade na agricultura urbana: o caso do bairro Curuçambá, Região Metropolitana de Belém
Authors: Fróes-Júnior Paulo Silvano Magno , Rebello Fabrício Khoury , Santos Marcos Antônio Souza dos , Martins Cyntia Meireles , Lopes Maria Lúcia Bahia , Loureiro João Paulo Borges de
Published: June 2022

O artigo analisa aspectos da gestão de negócios e competências empreendedoras de agricultores urbanos do bairro Curuçambá, município de Ananindeua, Região Metropolitana de Belém, considerando as dinâmicas do processo de urbanização vivenciado nas cidades da Amazônia e dos riscos da criminalidade. Foram entrevistados 63 agricultores e constatou-se que 98,41% dos negócios são geridos pela família, mas 52,38% têm pouca experiência com práticas de gestão, pois 76,19% nunca realizou qualquer tipo de registro econômico-financeiro da produção e 81,71% nunca procurou assistência técnica e empresarial. A criminalidade foi avaliada com grau de severidade “muito alta” por 33,33% dos agricultores e a falta de segurança pública limita, principalmente, o desempenho comercial, mudando perspectivas de comercialização e investimentos na agricultura urbana.
Functional outcomes of distal tibia fractures treated using the minimally invasive percutaneous plate osteosynthesis technique with a locking compression plate
Authors: Sivanandan M. Hari , Nanthivarman Nanthivarman , Jose Leo , Manoharan A. E.
Published: June 2022

Background: Distal metaphyseal tibia fractures are difficult to treat owing to their limited blood supply, subcutaneous location, and inadequate soft tissue blanket. Minimally invasive percutaneous plate Osteosynthesis (MIPPO) using a locking compression plate (LCP) is a widely used surgical treatment. It is beneficial for the management of distal tibia fractures. This study aimed to assess the functional outcomes of distal tibia fractures treated with the MIPPO technique with an LCP. Methods: The investigators have conducted this prospective study with thirty patients who presented with distal tibia fractures over 8 months. All patients fulfilling the inclusion criteria and exclusion criteria took part in the study. All the patients were surgically managed by the MIPPO technique with LCP under spinal or general anesthesia. The functional and radiological outcomes were evaluated with the American Orthopedic Foot & Ankle Society (AOFAS) scale. Results: A sizable number of the patients were aged 40–60 years, with a mean age of 49.8 years. Most participants were male (66.67%). The mean duration of surgery was 72.60 ± 5.35minutes. The mean length of hospital stay was 7.22 ± 1.45 days.
Assessment of the effect of different covid 19 vaccines on liver enzymes for corona patients in Diyala governorate
Authors: Jasim Hayder nsiefe , Zarzoor Ameerah Mrebee
Published: June 2022

In Diyala Governorate, a region within Iraq, the number of people infected with Corona disease began to increase rapidly during the year 2021 and after discovering the appropriate and safe vaccine against Corona, and studying what is  The best of these three covid19 vaccines types that reduce the severity of the disease and the effect of the disease on the liver by knowing the numerical changes on the liver enzymes, which include GOT, GPT and ALP, as well as comparing these variables between the vaccinated and the unvaccinated, the numbers were between 50 samples representing the control and they are for healthy, and 50 samples of unvaccinated corona patients and 300 samples of corona patients had received a vaccine in the past, the conclusion was that Corona patients may have changes in liver enzymes that rise slightly, Vaccination is play role in regulation liver functions through the increase or decreases parameters that related to it. The present study shows a significant difference between vaccinated and unvaccinated COVID-19 patients according to GOT, GPT and ALP parameters. These results show important vaccines in the regulation of liver function in COVID-19 patients.
Computational approach confirming the therapeutic potential of selected mannose derivatives against fimH of Uropathogenic E. coli
Authors: Chowdhury Abhishek , Choudhury Manabendra Dutta , Laskar Monjur Ahmed
Published: June 2022

Urinary tract infection (UTI), mainly caused by uropathogenic Escherichia coli (UPEC), is a dreaded infectious disease globally. FimH is a key virulence factor in UTI pathogenesis and inhibition of FimH function can be an effective way to disarm the UPEC bacteria and can act as a vital target in the development of the non-antibiotic mediated approach to treat UTIs. The present study was undertaken to identify phytochemicals from the cranberry and bearberry plant parts and to evaluate their pharmacological properties. The pharmacological properties of those compounds were predicted using a computational approach. The compounds with similar pharmacophores with that of known fimH inhibitors were selected. After that, further studies were performed to determine their drug likeness, inhibitory potential, and IC50 values. The results were promising, and few compounds were found to have high drug likeness and a potent inhibitor of fimH with good IC50 value. Thus, the present study reports few novel fimH inhibitors from selected plant sources and is significant owing to their therapeutic implication as a non-antibiotic mediated therapy for UTI.
Factors influencing satisfaction of antenatal service quality in public and private hospitals in Lusaka, Zambia
Authors: Castillo, Jr. Fermin G. , Nonde Linda Kasonka , Tawdrous Maher Ibrahim
Published: June 2022

Almost all maternal deaths occurring in developing countries are due to complications arising during antenatal, intra-partum and immediate postnatal period. Of these deaths more than half of them occur in sub-Saharan Africa and one third occur in South Asia. Most causes of these deaths are easily preventable through antenatal care in pregnancy, skilled care during childbirth, and care and support in the weeks after childbirth. In many African countries the coverage antenatal is increasing but the coverage alone does not provide information on quality of care, and poor quality in antenatal, clinics, correlated with poor service utilisation, is common in Africa. The purpose of this study was to assess factors influencing antenatal service quality in public and private health facilities in Lusaka District, Zambia, focusing on expectant mothers’ perspectives. A cross-sectional, descriptive, correlational design was used to examine the relationships between expectations, the quality of antenatal, personal characteristics and the type of provider with overall satisfaction, as well as with satisfaction with each of the following dimensions: Tangibility, reliability, responsiveness, assurance and empathy.
Community-based survey on the myths and use of contraceptive methods among married adults in Calabar South, Nigeria
Authors: Hannah Thompson Udom , Okpa John Thompson , Wilson Nwosu Uchechukwu , Bassey Obeten Ude , Eshiost Emmanuel
Published: June 2022

Background: Despite the enormous benefits associated with contraceptive use, only a few sexually active married adults in developing countries like Nigeria use contraceptive methods, this situation is even worst in rural areas across Nigeria. This study examines the influence of myths on the use of contraceptive methods in Calabar South Local Government Area, Cross River State, Nigeria. Methods: Using the mixed approach, data were obtained from 600 respondents, using a multi-stage sampling technique which in this study entails the selection of community clusters, streets, villages, housing units and respondents through simple random and purposive sampling techniques. In the analysis and interpretation of study findings, descriptive statistics were employed, and qualitative data were analyzed using content analysis. Results: The study shows that fear of pregnancy-related complications and fear of infertility are significant determinants of contraceptive use in Calabar South LGA, Cross River State, Nigeria. Conclusion: The study, therefore, concludes that myths associated with contraceptive use are real and a strong factor that discourages most married adults from the use of contraceptive methods.
Estimation of some trace elements level in children with Entrobiasis in Babylon province, Iraq
Authors: Saeed Rwaa Shaker , Al-Masoudi Hayam Khalis
Published: June 2022

Background: Enterobiasis or pinworm infection is a common, contagious, parasitic infestation found mainly in children, and is caused by Enterobius vermicularis one of the most common human parasitic helminthes . Objective : The present study aimed to check the influence of enterobiasis  infections on some trace elements (serum zinc, iron, and copper) in children of Babylon province in Iraq. Methods : A total of ninety children participated in this study and their ages ranged between (2-12)years old , and included both sexes , All samples were collected cellophane tape technique then examined under light microscope. blood sample also collected to estimate the level of serum zinc, copper and iron by ELISA test in infected children. Results: the results show mean value of serum zinc of patients and control group were ( 79.34 ± 25.09), ( 86.40 ±25.54),( t= 1.251, p-value= 0.214) respectively , the mean value of serum copper in patients was ( 99.16 ± 36.23) and in control group were ( 103.59 ± 36.52),( t= - 0.544, p-value = 0.587), and the mean value of serum iron in patients with enterobiasis and control group were ( 104.80 ± 125.12), ( t= - 1.774, p- value= 0.08) respectively.
Differences in left ventricular wall thickness in aerobic weight-bearing exercise and non-weight-bearing exercise in elderly Mus Musculus
Authors: Syahida Deshinta Fitrianti , Susilo Imam , Wiyasihati Sundari Indah
Published: June 2022

Due to the process of aging, the function of human organs and muscles decreases. Exercise is a solution to improve organ and muscle function. But it all must be in proportion. So far, aerobic exercise is an exercise solution. This study aims to test the differences between the effects of aerobic weight- bearing exercise and aerobic non-weight-bearing exercise as a sports solution for the elderly. The experimental laboratory used a completely randomized post-test design using 30 mus musculus samples with three actions, namely 10 mus musculus that were not exercised, 10 mus musculus with aerobic weight-bearing exercise and 10 mus musculus with aerobic non- weight-bearing exercise. This process is carried out for 6 weeks with a frequency of exercise 5 times a week, and processed statistically using the statistical product and service solution (SPSS) program. There were significant differences between control group and both aerobic weight- bearing exercise and aerobic non-weight bearing exercise with both p-value being <0.05. However, aerobic weight-bearing exercise and aerobic non– weight-bearing exercise resulted in an enlargement of the ventricle sinistra but there was no significant difference between groups due to the post hoc Mann Whitney test, with p-value>0.05.
Reconsiderations with basic viral tests in Wasit blood bank: CMV and EBV as an examples
Authors: Alkhateeb Zainab Dhiyaa , Maleek Muthana Ibrahim , Faraj Safaa Abdalelah
Published: June 2022

Background: Blood donation is a procedure of collecting blood from a screened person who must follow the strict guidelines in the country where peoples lived. Aim of the study: To increase the safety of blood given to patients by evaluating the addition of new investigations to detect CMV and EBV infection of donated blood in the blood bank in Wasit Governorate. Patients and Methods: This study included 150 samples of blood taken from blood bags of donors from blood bank /Wasit Province. In this study used ELISA used only for detect infection with CMV and Real-Time PCR were used to detect infections with CMV and EBV. Results: The results of ELISA from 150 analyzed samples only 30/150 (20%) of the patients were diagnosed infection by CMV. While the results of RT-PCR 50/150 (33.3%) for the same virus, and the results of RT-PCR 13/150 (8.7%) for EBV. Conclusion: The guideline of blood and blood product donation should be reviewed to keep up the updated guideline of WHO to provide more suitable medical services to community.
Study on genetic divergence in various genotypes of watermelon [Citrullus lanatus (Thunb.) Mansf.].
Authors: Singh U , Kumar S , k Archana , k Chaman , Yadav K , Gola SK , k Sidharth
Published: June 2022

The results of the analysis of variance indicated that substantial genetic variability was present for yielding contributing characters. The intra-cluster distance was recorded as the highest for cluster 3 (49.75) which indicates the existence of maximum variability within this cluster. The inter-cluster distance was maximum between clusters 5 and 6 (94.81) which indicates that the genotypes included in these clusters are genetically diverse. So, it is desirable to select accessions from the clusters having high inter-cluster distance in the recombination breeding programs. The minimum inter-cluster distance was observed between cluster 1 and cluster 5 (50.92), indicating the close relationship among the genotypes included in these clusters. Based on yield and yield contributing characters, the genotypes viz., VRW-14, VRW-12, VRW- 20 and VRW-17 were found promising for the future improvement programme.
Screening of onion species against white rot disease caused by Sclerotium rolfsii Sacc. in Manipur
Authors: Konjengbam R , Devi RT
Published: June 2022

White rot of onion caused by Sclerotium rolfsii has devastated onion cultivations at various small scale onion growing locations in Manipur. The maximum white rot disease incidence was observed during the month of April in all the onion species and the minimum disease incidence was observed during February month. The disease symptoms were not apparent during the first three months after planting. The symptoms of white rot became evident during second week of February with yellowing of leaves starting from tips and gradually progressing downwards. The disease became most obvious during last week of March to first week of April when the basal part of onion stem starts rotting and drooping and the plant wilts and collapse. The bulbs of infected plants are decayed and accompanied by the signs of the pathogen including white mycelium and sclerotia.
What does it mean to represent? Mental representations as falsifiable memory patterns
Authors:   Institute for Neural Computation, Ruhr University Bochum, Parra-Barrero Eloy , Sandamirskaya Yulia ,   Neuromorphic Computing Lab, Intel Labs, Munich
Published: June 2022

Representation is a key notion in neuroscience and artificial intelligence (AI). However, a longstanding philosophical debate highlights that specifying what counts as representation is trickier than it seems. With this brief opinion paper we would like to bring the philosophical problem of representation into attention and provide an implementable solution. We note that causal and teleological approaches often assumed by neuroscientists and engineers fail to provide a satisfactory account of representation. We sketch an alternative according to which representations correspond to inferred latent structures in the world, identified on the basis of conditional patterns of activation. These structures are assumed to have certain properties objectively, which allows for planning, prediction, and detection of unexpected events. We illustrate our proposal with the simulation of a simple neural network model. We believe this stronger notion of representation could inform future research in neuroscience and AI.
CSR Initiative as a PR Strategy during the COVID-19 Pandemic
Authors: Lang Lang
Published: June 2022

The coronavirus (COVID-19) pandemic has resulted in a sharp decrease for worldwide businesses. Protecting market share and reputation seems to be crucial during this crisis. Many companies believe connecting corporate social responsibility (CSR) with business responses is an effective solution and a great opportunity to change into more genuine CSR and prevent their asset from losses. This essay will concentrate on business responses related to COVID-19 and the corresponding impact of CSR initiatives in the pandemic. It will then give public relations (PR) implications to guide companies to the most reliable and efficient way to maintain and improve their stakeholder engagement.
Analysis on the Innovation Path of Enterprise Human Resource Management in the Era of Digital Economy
Authors: Liao Keyu , Zhang Jinghao
Published: June 2022

In the era of digital economy, with the rapid development of society and economy, the market competition among enterprises is becoming more and more fierce, and they are facing greater development pressure. Human resources are an important manifestation of the competitiveness of an enterprise, and various management tasks rely on the support of talents. Therefore, enterprises should analyze the development of the digital age, innovate and improve human resource management measures, fully mobilize employees' enthusiasm for work, encourage employees to maximize their value in their positions, and help enterprises move towards a better stage of development. There are problems such as lack of incentive measures in human resource management and control in modern enterprises, which will have a negative impact on the development of enterprises. This article discusses the effective path for enterprises to innovate human resource management in the era of digital economy, in order to provide reference.
Meningkatkan Koordinasi Gerak Tangan Anak Usia 5-6 Tahun pada Tari Sunda melalui Aplikasi TikTok di PAUD Permata Hati
Authors: Nasem Nasem , Iskandar Yogha Zulvian , Kusmiati Ety
Published: June 2022

Penelitian ini bertujuan untuk mengetahui manfaat Tari Sunda Melalui Aplikasi TikTok dalam meningkatkan Koordinasi Gerak Tangan Anak Usia 5-6 Tahun. Penelitian ini merupakan penelitian kualitatif dengan metode studi kasus. Hasil penelitian ini menunjukkan bahwa tari merupakan salah satu bentuk seni yang di dalamnya memadukan motorik kasar dan motorik halus. Gerak dasar tari sunda pada anak usia dini memerlukan koordinasi gerakan tangan. Di PAUD Permata Hati, beberapa anak belum dapat mengkoordinasikan gerakan tangan pada gerak dasar tari sunda. Hal ini terlihat pada kecepatan gerakan tangan dengan iringan dan musik, koordinasi gerakan tangan, dan fleksibilitas (kelenturan gerakan tangan) anak di PAUD Permata Hati. Untuk menstimulasi perkembangan koordinasi gerakan tangan saat melakukan gerak dasar tari Sunda maka PAUD Permata Hati mencoba menggunakan aplikasi TikTok. Aplikasi TikTok merupakan media sosial yang sedang trend di kalangan anak-anak maupun remaja. Aplikasi ini memudahkan seseorang untuk mengekspresikan perasaan, melalui tulisan, lagu, video maupun simbol sederhana lainnya, dengan menggunakan aplikasi tiktok diharapkan anak-anak dapat mengkoordinasikan gerakan tangan saat melakukan gerak dasar tari Sunda. Penelitian ini menggunakan kuantitatif deskriptif dalam bentuk penelitian tindakan kelas.
Pengaruh Kompetensi, Kepuasan Kerja dan Iklim Organisasi terhadap Kinerja Pegawai pada Sekolah Menengah Kejuruan Persada Makassar
Authors: Muliyadi Muliyadi , Adi Yusram , Hafipah Hafipah
Published: June 2022

Penelitian ini bertujuan Untuk mengetahui Seberapa besar pengaruh Kompetensi, kepuasan kerja dan Iklim Organisasi terhadap kinerja pegawai di Sekolah Menengah Kejuruan Persada Makassar. Populasi yang digunakan dalam penelitian ini adalah seluruh pegawai di SMK Persada Makassar dan Guru yang difungsikan sebagai Pegawai berjumlah 48 Orang dengan menggunakan Sampel jenuh karena yang dijadikan Populasi itu juga yang dijadikan Sampel. Dengan meneliti kehadirannya selama tiga tahun berturut-turut, Yaitu pada tahun 2018, 2019 dan 2020. Metode analisis data yang digunakan adalah penelitian asosiatif, atau penelitian yang akan menguji ada tidaknya pengaruh antara variabel yang dikaji, dengan menggunakan data berjenis kuantitatif, (singarimbun et.al., 2005:5), dengan pengujian analisis : Uji Normalitas. Uji Validitas dan uji Reliabilitas dengan Formulasi koefisien adalah pearson Product test dengan program spss versi 23.00. Berdasarkan pengujian secara simultan Kompetensi, kepuasan kerja dan iklim organisasi terhadap Kinerja Pegawai berpebgaruh Positif dan Signifikan.
Manajemen Parenting dalam Meningkatkan Kemandirian Anak Usia Dini
Authors: Mujapar Ahmad , Barlian Ujang Cepi , Soro Suharyanto H.
Published: June 2022

Adapun tujuan penelitian ini secara khusus adalah ingin mengetahui perencanaan, pelaksanaan, evaluasi, dan kendala yang dihadapi pada manajemen parenting dalam meningkatkan kemandirian anak usia dini. Dalam penelitian ini, peneliti menggunakan metode Deskriptif Kualitatif. Adapun hasil dari penelitian ini adalah kedua Raudhatul Athfal masing-masing telah melaksanakan: 1) Perencanaan parenting dalam meningkatkan kemandirian anak usia melalui kegiatan rapat kerja awal tahun ajaran oleh pihak sekolah bersama orang tua/wali murid. Proses perencanaan meliputi penetapan kegiatan dan materi yang akan dilaksanakan seperti kelas pertemuan orang tua seperti seminar dan hari konsultasi, dan kelas keterlibatan orangtua dalam acara bersama seperti outbound dan cookingclass yang dicantumkan pada kalender akedemik sekolah, waktu dan tempat pelaksanaan. 2) Pelaksanaan parenting memiliki beragam tujuan diantaranya adalah sebagai wadah silaturahmi, penyampaian visi misi sekolah,  menyamakan tujuan dengan orang tua dalam pendidikan dan pengasuhan anak usia dini meningkatkan kemandirian anak usia dini. Bentuk pelaksanaan program  parenting ada dua: 1) Kelas pertemuan orangtua dalam bentuk seminar.  2) Kelas keterlibatan orangtua dalam acara bersama dalam bentuk outbond dan cookingclass. 3)Evaluasi parenting terdiri dari: (a) Evaluasi yang dilakukan pada saat pelaksanaan kegiatan parenting dengan orang tua melalui diskusi dan tanya jawab. (b) pengawasan dan evaluasi yang dilakukan setelah kegiatan program parenting. 4) Kendala teknis proses pelaksanaan program parenting yang dihadapi adalah kurangnya kerjasama yang baik antara lembaga RA dan wali murid  Menurut G. R. Adapun kesimpulan dari penelitian ini adalah manajemen parenting dapat meningkatkan pemahaman orangtua terhadap proses pelaksanaan kegiatan parenting. Penelitian ini direkomendasikan untuk dinas pendidikan, orangtua, RA Alfaiz dan RA Assyafi, iyah dan bagi peneliti selanjutnya.
Marketing Performance pada UKM: Peran Entrepreneurial Markeeting
Authors: Santi Ira Nuriya , Fadjar Adfiyani , Putra Setiawan Mandala
Published: June 2022

Penelitian ini adalah penelitian kuantitatif yang bertujuan untuk mengetahui hubungan entrepreneurial marketing dengan sales growth, market share, dan customer satisfaction. Sampel yang digunakan dalam penelitian adalah pelaku Usaha Kecil Menengah yang ada di Kota Palu. Pengambilan sampel menggunakan metode non probability sampling dengan teknik convenience. Teknik analisis data mengunakan teknik structural equation modeling dengan menggunakan alat bantu SmartPLS.  Hasil analisis data bahwa hubungan entrepreneurial marketing dan sales growth positif dan signifikan. Entrepreneurial marketing dan market share memiliki hubungan yang positif dan signifikan. Serta hubungan entrepreneurial marketing dan customer satisfaction positif dan signifikan.
Features of coronary artery bypass grafting in young patients with acute coronary syndrome
Authors: Aliyev Ramil , Musayev Kamran
Published: June 2022

Aim: Purpose of the study was retrospective analysis of hospital and early (up to six monthes after operation) results of the surgical myocardial revascularization in patients, third and fourth decates of life, with acute coronary syndrome.
Material and Methods: Since 2012 year up to November, 2018 year in CCH by the same brigade, performed 500 coronary artery bypass grafting operations in the patients with acute coronary syndrome, at the age of 30-83 years old, including 15 operations in patients ≤ 40 years old (3%). Clinical manifestation of acute coronary syndrome was presented: unstable angina in 13 (86.7%) patients, 6 (40%) of them with pass myocardial infarction in anamnesis; acute myocardial infarction, accompanied by S-T segment elevation (STEMI) in 2 (13.3%) patients. In coronarography: multivessel lesion of coronary arteries was revealed in 10 (66.7%) patients, 3 of them with lesion of trunk of the left coronary artery; bivascular lesion in 4 (26.7%) patients, single vessel lesion in 1 (6.6%). In 13 (86.7%) patients were performed coronary artery bypass grafting under the cardiopulmonary bypass (CPB). Average duration of the CPB= 127±9.66 min. Mean aortic clamp time = 68±6.91 min. Number of shunts for the whole group of 15 operated were from 1 to 5, at the average (3.28±0.31). In 6 patients (40%) performed three-branches CPB, in 5 patients (33.3%) fourth-branches, in 1 patient (6.7%) fifth-branches, in 2 patients (13.3%) double-branches and in 1 patient (6.7%) single branch CPB. Used conduits: left internal mammary artery in all 15 patients (100%), autovein in 12 (80%), radial artery in 10 (66.7%) patients. In last group with using radial artery, average amount of shunts was 1.5±0.1.
Results: The structure of postoperative complications consist: low cardiac output syndrome in two patients; bleeding in 2 patients. In analyzed series, no lethal outcomes watched in duration up to 30 days after operation. All patients were watched during 6 monthes after discharge. It was not watches necessity for reinterventions and lethal outcomes.
Conclusion: Hospital and immediate results of myocardial revascularization in young people with acute coronary syndrome very encouraging, while long-term results are not so optimistic and unsatisfactory. Therefor, considering the long life expectancy and higher functional and social demands of the patients at age ≤ 40 years, preference is given to hybrid interventions or isolated shunting using arterial conduits in both variants of revascularization.