bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of indole borate ligand with Ni(II) and Cu(II) complexes
Authors: Mohammed Noori Khaleel Asmaa
Published: January 2025

A new borate derivative (2,2',2'',2'''-((ʎ4-boranetetrayl)tetrakis(1H-indole-1,3-diyl))tetraacetic acid)(BIN) was synthesized from the reaction of indole-3-acetic acid (IAA) with sodium tetrahydroborate NaBH4  at a 4:1 mole ratio. This ligand was characterized by 1HNMR, FTIR, electronic spectra (UV-Vis.) thermal analysis (TG and DTG), elemental analysis (CHN) and melting point. Nickel and copper complexes were also synthesized and characterized by CHN, UV-Vis, atomic absorption, FTIR, melting point, magnetic susceptibility and molar conductivity. Results of analyses were in agreement with suggested structures. The results showed that the structure of nickel complex was octahedral while the copper complex was square planar and both complexes were nonelectrolytes. Antimicrobial activity against four kinds of bacteria Staphylococcus aureus and Streptococcus (G+), E. coli and Pseudomonas aeruginosa (G‒) as well as one fungus Candida albican exhibited that the copper complex has higher antimicrobial activity. Total antioxidant results showed that the BIN ligand has higher activity at 50 and 100 μg/mL while the copper complex has more antioxidant activity at 150 μg/mL.
Bull. Chem. Soc. Ethiop. 2025, 39(4), 703-712.                                                           
DOI: https://dx.doi.org/10.4314/bcse.v39i4.8
In silico evaluation of verbenone and selected solubilizing compounds against diabetes-related proteins
Authors: Saliu Oluremi A. , Edogbo Blessing , Nasir Suwaiba , Adamu Shehu Usman , Sada Salima Adamu , Abdullahi Adamu , Idowu Ayodeji O. , Adams Moses Dele , Tijjani Habibu
Published: January 2025

Verbenone is a colourless, minty liquid that is soluble in non-polar solvents with in vitro and in vivo antidiabetic activities. This study evaluates verbenone and selected solubilizing compounds in silico against diabetes related proteins which included glucokinase (1V4S), human pancreatic α-amylase (1B2Y), and sucrase-isomaltase (3AXH). The structures of verbenone, acarbose, and five identified solubilizing compounds were downloaded in SDF format from the PubChem database. The binding energies were computed using Autodock Vina software while physicochemical properties and ADME parameters were predicted using SwissADME server. In glucokinase and human pancreatic α-amylase, the binding affinity (Kcal/mol) of verbenone (-5.4, -5.9) was superior to lysine (-4.5, -4.7) and eudragit (-4.5, -3.6), while in sucrase-isomaltase, the binding affinity (Kcal/mol) of verbenone (-6.1) was superior to lysine (-5.2), cyclodextrin (-4.8) and eudragit (-4.0) respectively. Only cyclodextrin violated the Lipinski rule of five. More so, cyclodextrin, lysine and eudragit are very soluble, with low lipophilicity compared with verbenone. Lysine and eudragit possess high gastrointestinal absorption and are not suitable P-gp substrate, while eudragit can effectively cross blood brain barrier. The study identified cyclodextrin, lysine and eudragit as potent candidates to improve the bioactivity of verbenone, as alternate means to improve the antidiabetic activity of verbenone.
Enhancing plantation productivity: A screen-house investigation into the impact of indaziflam on amaranthus, maize, melon, and tomato in intercropping systems
Authors: Imomoh Isesele John , Ayodele Olatunde Philip , Ikuenobe Celestine Ebehiremhe
Published: January 2025

The potential impact of the new indaziflam pre-emergence herbicide on common plantation intercrops of amaranthus, maize, melon, and tomato, was assessed in a screenhouse study. The experimental treatments comprised the following inclusion of indaziflam to soil at sowing: 0, 0.15, 0.30, 0.45, 0.60, and 0.75 mg/kg. These treatments were laid out in a completely randomized design with four replications. The effect of indaziflam was evaluated through destructive sampling after 8 weeks of growth, and its residual effect was examined post-replanting after the same period, specifically at 16 weeks following indaziflam application. Data on plant height, number of leaves, leaf area, plant fresh weight, and plant dry weight were recorded in each planting instance. The collected data were subjected to analysis of variance, and the treatment means were separated using Duncan's New Multiple Range Test at a significance level of 5%. The study revealed significant reductions (p ≤ 0.05) in growth of the test crops due to indaziflam application, with the most pronounced effects at higher concentrations. Amaranthus and tomato seedlings failed to emerge at concentrations > 0.15 mg/kg and ≥ 0.15 mg/kg, respectively. Maize and melon exhibited reduced growth at concentrations > 0.3 mg/kg. Residual effects were significant, notably reducing plant growth parameters at higher indaziflam concentrations, particularly at 0.6 and 0.75 mg/kg. In conclusion, indaziflam at concentrations greater than 0.15 mg/kg significantly inhibits the growth of common plantation intercrops, with persistent residual effects, suggesting its limited suitability for use in such contexts.
Impact of nematicides on plant-parasitic nematodes: Challenges and environmental safety
Authors: Tiwari Srijan
Published: January 2025

Plant Parasitic Nematodes (PPNs) are tiny, pseudocoelomate, unsegmented, bilaterally symmetrical vermiform animals that attack plants. Nematicides are chemically synthesized substances that kill or harm nematodes. Between 1940 and 1950, three chemicals with nematicidal properties were discovered: methyl bromide (bromomethane), D-D mixture, and EDB (1, 2-dibromoethane; as ethylene dibromide) which were fumigants. When fumigant compounds are applied to soil, a gas moves through the open spaces between soil particles or into the water film that surrounds soil particles. Fumigants significantly decrease nematode respiration by oxidizing Fe2+ centers and alkylated proteins in the cytochrome-mediated electron transport chain. Despite the efficacy of fumigants in nematode, their use was lowered due to the high environmental risk of these products. A new generation of nematicides was introduced: carbamates and organophosphates that served as contact nematicides, which led to the testing and development of other non-fumigant nematicides such as aldicarb, carbofuran, ethoprop, and fenamiphos. The carbamates and organophosphates acetylcholinesterase inhibitory properties prevent normal nerve impulse transmission in the nematode nervous system. Nematicides are typically non-selective pesticides, and their use impacts non-target organisms, humans, and the environment. Since nematicides are toxic to humans, soil, groundwater, and non-target organisms, cautious nematicide selection and application are vital. New compounds that are less aggressive and more specific for PPNs have been developed, making them safer for the producer, consumer, and environment. Crop rotation, cover crops, organic manuring, use of resistant varieties, and other methods must be integrated with nematicides for increased effectiveness.
AUTISMO E INCLUSÃO
Authors: Camargo Neuza Maria Guimarães Franco , Souza Átila de , Malta Daniela Paula de Lima Nunes , Fagundes Eliene Andrade , Botelho Sandra de Oliveira
Published: January 2025

O presente trabalho aborda a temática da inclusão de crianças autistas em escolas de ensino regular, destacando a importância de uma abordagem estruturada e qualificada. O autismo é uma síndrome de desenvolvimento global que afeta a capacidade de interação e expressão dos indivíduos, apresentando desafios específicos no contexto educacional. O principal objetivo do estudo é compreender como deve ser realizada a inserção de crianças autistas em escolas regulares, considerando os aspectos necessários para garantir um processo inclusivo e efetivo. A pesquisa foi desenvolvida por meio de uma abordagem bibliográfica, utilizando como base livros, artigos científicos e trabalhos acadêmicos publicados. Os principais autores que embasaram o estudo incluem Mittler (2007), Mantoan (2003), além das legislações Brasil (1996) e Brasil (2008). A inclusão de crianças autistas no ensino regular requer planejamento e metodologias específicas que promovam um trabalho progressivo e eficaz. A interação entre a equipe escolar e a criança com necessidades especiais é essencial, formando a base para o progresso no processo de inclusão. O trabalho docente, aliado ao profissionalismo e à qualificação da equipe escolar, desempenha um papel central nesse contexto. Conclui-se que a atuação conjunta do professor e da equipe escolar é fundamental para a inclusão de crianças autistas, uma vez que o trabalho didático-pedagógico é o ponto de partida para esse processo. A implementação de práticas de ensino adequadas é determinante para o sucesso da escolarização de crianças com essa síndrome.
Hydromorphotectonic Analysis of Al Najaf-Karbala Plateau Using Remote Sensing Techniqe
Authors: Albhadili Suaad , Almallah Inass , Almulla Saher
Published: January 2025

Najaf-Karbala Plateau is located in the central part of Iraq with economic and environmental importance. The hydrological analyses of the plateau show six main watersheds, which provide a comprehensive examination of how surface and tectonic processes interact to shape geological structures in the area. Five morpho-tectonic parameters were applied; Asymmetry factor, Transverse topographic symmetry factor, Stream length gradient index, Mountain-front sinuosity and Elongation ratio. It was concluded that the area under study is activated tectonically to be potential watersheds, symbolized by WSh1, WSh2, WSh3, WSh4, WSh5and WSh6. The results show low tectonic activity across all watersheds based on to stream length gradient index, whereas three different levels of tectonic activity that based on the Mountain-front sinuosity. The watersheds have different tectonic levels; high activated at WSh1, WSh2, WSh4 and WSh6, while very high activated at WSh5. WSh3, on the other hand, has moderated activity over the area. However, the Elongation ratio indicated that the Najaf-Karbala Plateau exhibits elongation characteristics and more tectonic activity as well.
Evaluation of Fat'ha Formation’s Clays (Middle Miocene) in the Western Desert of Iraq for Portland Cement Industry
Authors: Al-Salmany Ali , Al-Hazaa Sawsan
Published: January 2025

The Fat'ha Formation (Middle Miocene) in the Western Desert of Iraq has been identified as a viable clay source for the Portland cement industry through comprehensive chemical and mineralogical analyses using XRF and XRD analysis. The clay beds of the Fat'ha Formation offer a promising alternative to the currently exploited Quaternary sediments, which are environmentally damaging and exhaust the availability of agricultural soil. The raw mix for cement production was calculated using the Allegation Alternative Method consisting of 67.56% limestone with 32.44% clay. The study indicates that the laboratory-produced clinker's properties and mineral phases are identical to industry standards for Portland cement manufacture. This confirms the formation's suitability as a sustainable raw material source for cement production.
Hukum Perikatan dalam Kontrak Internasional dan Implikasinya
Authors: Rohmah Umdah Aulia , Harsya Rabith Madah Khulaili , Pandu W Muhammad Arfianto , Putri Rifka Novia Ardhita
Published: January 2025

In an era of increasingly complex globalization, the legal regulation of international agreements is very important to ensure legal certainty in cross-border contracts. Challenges faced in the recognition and enforcement of ties, including differences in legal systems, jurisdictional conflicts, and juridical obstacles. The law of engagement serves as the basis of legal relations binding the parties to a contract, but its implementation is often hampered by differences in legal procedures and public order principles in different countries. Harmonization of law through international treaties, such as the United Nations Convention on Contracts for the International Sale of Goods (CISG) and the 1958 New York Convention, is proposed as a solution to overcome these differences. In addition, international arbitration is recognized as an effective dispute resolution mechanism, providing flexibility and certainty for the parties. This research uses a qualitative method with a descriptive-analytical approach to explore the dynamics of international binding law and its implications for the enforcement of rights and obligations in the context of international civil law. The results show that strengthening the international legal framework and collaboration between countries is necessary to create a stable and predictable business environment.
A Atuação do Tecnólogo em Radiologia na Medicina Veterinária- Um trabalho de campo.
Authors: De Souza Jonhny , Campos Fábio , De Souza Francisca , Valdevino Thácia , Rocha Ediane
Published: January 2025

A didática representa uma das conjunturas fundamentais do campo de atuação tecnológica da radiologia na história, sendo um ramo central das concepções a radiologia veterinária vem expandindo e trazendo métodos de diagnósticos cada vez mais sofisticados e com isso proporcionando rapidez na resolução dos casos clínicos na clínica de pequenos e grandes animais.  Ao contrário da medicina humana, na medicina veterinária o técnico e tecnólogo trabalham com várias espécies de animais totalmente diferentes daquela no qual está acostumado, a espécie humana. Mediante o fato supracitado, a necessidade de possuir profissionais devidamente capacitados no ambiente de imaginologia da medicina veterinário é de natureza carente e quase inexistente. Pensando nisso, o presente trabalho discute sobre a importância da participação do profissional radiologista frente ao setor de imagem, abordando parâmetros de exposição e fundamentos físicos do equipamento. Para tanto, seguindo os moldes do trabalho de campo enquanto base norteadora da referida pesquisa, foi-se utilizado dados do Hospital Veterinário do Centro Universitário de Patos – UNIFIP, durante 6 meses do período letivo do semestre de 2023.2 conseguinte ao estágio supervisionado de radiologia médica veterinária, nela foi abordado protocolos de exposição em equipamento de raio- x como cálculos de espessura da área irradiada, Kv e mAs em cães e gatos, levando em consideração que o presente equipamento era comumente utilizado na área médica humanista.
Isotopic Phenomenon: Case Report and Distinctions Between the Isomorphic Phenomenon, Inverse Isomorphic Phenomenon and the Sign of Pathergy
Authors: Kondo Rogério Nabor
Published: January 2025

The isotope phenomenon, also called the Wolf’s isotopic response, refers to the emergence of a new skin disease at the exact location of a previously cured unrelated skin disease, often following infection with the herpes zoster virus. We report a case of isotopic phenomenon and provide brief comments on the distinctions between the isomorphic phenomenon, inverse isomorphic phenomenon and sign of pathergy.
Pobre concordancia en la interpretación de eventos adversos neurológicos después de la inmunización con vacunas contra el SARS-CoV-2. Estudio de una serie de casos.
Authors: Nader-Kawachi Juan , Flores-Silva Fernando Daniel , Del Brutto Oscar H. , Gutierrez-Romero Alonso , Pino-Peña Yaima , Flores-Aldama Marco , Soto-Ramírez Luis , Peniche-Echazarreta Adriana
Published: January 2025

Antecedentes: Una proporción considerable de la población mundial ha sido vacunada para prevenir infección por SARSCoV-2. En la práctica clínica, sin embargo, casi cualquier manifestación neurológica que se produzca después de la vacunación se ha atribuido a la vacuna, generando dudas sobre su seguridad. En 2013, la OMS creó los criterios de Efectos Adversos Posteriores a la Inmunización (AEFI), por sus siglas en inglés, para establecer la relación entre una vacuna y sus efectos secundarios, pero éstos parecen no disipar las dudas sobre la gravedad y la causalidad de la vacunación.

Métodos: Se midió el nivel de concordancia mediante la metodología kappa de Fleiss. Diecisiete observadores (cinco neurólogos, cuatro especialistas en enfermedades infecciosas y ocho residentes de medicina interna) calificaron de forma independiente 11 casos tratados en nuestro servicio, que presentaban síntomas neurológicos dentro de los 21 días posteriores a la vacunación contra el SARS-CoV-2 según los criterios de la AEFI.

Resultados: Se encontró pobre concordancia entre los 17 evaluadores en cuanto a severidad (k=0,088) y causalidad (k=0,025). Al analizar por subgrupos de evaluadores, la concordancia para la gravedad fue moderadamente mayor entre los neurólogos (k =0,383) y para la causalidad entre los residentes de medicina interna (k = 0,117).

Conclusiones: Los criterios AEFI no permiten, por sí solos, establecer la relación entre una vacuna y efectos neurológicos adversos. Por lo tanto, es esencial crear herramientas más útiles que permitan a los médicos y legos tener más confianza en este desafío.
Predictores de ansiedad durante la pandemia COVID-19 en estudiantes de medicina de Morelos, México.
Authors: Betanzos-Díaz Norma , Petricevich Vera Lucía , Paz-Rodríguez Francisco
Published: January 2025

Introducción: Los estudiantes del área médica son un grupo de interés ante la aparición de COVID-19, ya que las medidas de distanciamiento social pueden afectar su ansiedad y ser vulnerables al impacto emocional, debido a que la profesión forma parte de la primera línea de atención ante esta pandemia.

Objetivo: Describir la prevalencia y predictores de la ansiedad ocasionado por la pandemia COVID-19 en estudiantes universitarios de medicina de Morelos, México.

Método: Estudio observacional descriptivo de corte transversal mediante cuestionario online, incluyó Caracterización Sociodemográfica, Desorden de Ansiedad Generalizada (GAD 7), Pasión por el Estudio, Escala de autocompasión (SCS), Escala de Resiliencia Connor-Davidson (CD-RISC), Satisfacción Vital y Escala de Desmoralización (DS).

Resultados: En una muestra de 292 estudiantes de medicina, mujeres (62,8%), mayores de 21 años (66,9%), un 72,7% reportó ansiedad y 65,5% problemas de sueño. El modelo de regresión múltiple obtenido muestra que la disforia es la variable que mayor capacidad predictiva de importancia reporta con un 34,8%, le sigue el tener problemas para dormir con un 24,4%, el desánimo 22,4%, la sobre identificación 13,9% y la preocupación por contagiarse 4,5%.

Conclusiones: La preocupación e incertidumbre en los ambientes hospitalarios donde se preparan y forman los estudiantes de medicina, aumentan el riesgo de ansiedad, por percibir condiciones adversas y frustración como parte de su profesión.
Evaluación de la función cognitiva diaria del adulto y adulto mayor mediante el uso del ECog (everyday cognition).
Authors: Almaguer-Rodríguez Alejandro G. , Riquelme-Heras Héctor , Gómez-Gómez Celina , Méndez-Espinosa Eduardo , Gutiérrez-Herrera Raúl , Ordoñez-Azuara Yeyetzy
Published: January 2025

Introducción: Adultez mayor es la etapa de la vida donde ocurren cambios biológicos importantes como la disminución de la función cognitiva. El ECog es una herramienta útil para detectar cambios iniciales en la disminución de la función cognitiva y deterioro cognitivo subjetivo. Puede ser contestado por un informante(familiar) sin necesidad de estar presente el paciente, se puede aplicar a pacientes de bajo nivel educativo o con alguna discapacidad, sin ser esta una limitante.

Objetivo: Conocer los cambios en la función cognitiva diaria del adulto y adulto mayor por décadas. (50-59, 60-69, >70años) mediante el ECog.

Material y Métodos: Estudio descriptivo, transversal, aleatorizado, tipo encuesta. Se incluyeron pacientes mayores de 50 años que acudieron a consulta de Medicina Familiar, por cualquier motivo diferente a demencia, se excluyeron pacientes que no desearon participar y se eliminaron encuestas incompletas. La n fue de 180 pacientes, 60 pacientes por cada grupo de edad (grupo 1=50-59 años, grupo 2=60-69 años y grupo 3=>70 años). Se aplicó a los pacientes el ECog (contestado por un informante). Se calcularon las medias por grupo de edad, se calculó la variación entre cada grupo utilizando una fórmula de comparación de medias, se calculó la prevalencia de Deterioro Cognitivo Subjetivo (punto de corte en ECog>1.36) por grupos de edad y los dominios más afectados.

Resultados: La disminución de la función cognitiva medida mediante el ECog aumentó conforme avanza la edad de manera significativa entre cada grupo (Anova p menor a 0.001), así como la prevalencia de casos con Deterioro Cognitivo Subjetivo. Las funciones más afectadas fueron la memoria, la atención y la organización. El dominio menos afectado fue el lenguaje.

Conclusión: Se observó un cambio significativo de la disminución de la función cognitiva conforme avanza la edad. El ECog es una excelente herramienta, fácil y sencilla de utilizar para el médico de Atención Primaria.
Análisis neuropsicológico en un caso de Afasia Global.
Authors: Ramos-Galarza Carlos , Gaibor-Estévez Jhonny
Published: January 2025

El daño cerebral adquirido genera una serie de alteraciones neuropsicológicas, entre las cuales, se puede resaltar la Afasia. Este síndrome se caracteriza por una alteración del lenguaje, siendo sus principales características déficits en la fluidez, comprensión, repetición, denominación, lectura, escritura y cálculo. En este artículo presentamos el caso de un paciente que sufre una afasia global, quien presenta severas alteraciones a nivel lingüístico. Se analiza el estado de la enfermedad y su condición neuropsicológica. Finalmente, se cierra este análisis, resaltando la necesidad de contar con un correcto abordaje neuropsicológico a nivel de diagnóstico y rehabilitación que puedan ayudar significativamente al paciente.
Encefalomielitis aguda diseminada tras infección por herpes virus
Authors: Ramón y Cajal Calvo Juan , Romero Martinez Jorge , Raymundez Valhondo Javier , López Negredo David
Published: January 2025

La encefalomielitis aguda diseminada (ADEM, por sus siglas en inglés) es un proceso inflamatorio y desmielinizante rápido del sistema nervioso central (SNC), afectando la sustancia blanca principalmente, pero también la sustancia gris. Suele ocurrir tras infecciones virales o vacunas. Se presenta el caso de una paciente de 26 años con síntomas sensoriales y debilidad en extremidades izquierdas. Las pruebas muestran lesiones cerebrales y cerebelosas con posible desmielinización. Se sospecha ADEM debido a antecedentes de herpes zóster. Se administran corticosteroides con evolución satisfactoria. La ADEM es un proceso grave que puede afectar a niños y adolescentes, y presenta hallazgos en resonancia magnética similares a Esclerosis Múltiple (EM). El diagnóstico es excluyente, el tratamiento es con corticosteroides, pero puede dejar secuelas.
Gestión de Residuos y Responsabilidad Social Empresarial en el Reciclaje de Neumáticos en Ecuador: Un estudio de oportunidades y desafios
Authors: Tipán Tapia Luis
Published: January 2025

Este estudio analiza las estrategias de gestión de residuos y las prácticas de Responsabilidad Social Empresarial (RSE) implementadas por tres empresas líderes en el reciclaje de neumáticos fuera de uso en el Ecuador. A través de un enfoque cualitativo a través de entrevistas cualitativas a expertos, se identifican las principales oportunidades y desafíos que enfrenta el sector, como el cumplimiento normativo, incorporación de la tecnología, desvulcanización química, y el rol de la formación profesional para garantizar la sostenibilidad ambiental. Los hallazgos revelan que el éxito de las empresas analizadas depende de su capacidad para integrar modelos de economía circular en sus operaciones, a la vez gestionan los altos costos de las tecnologías emergentes y superan barreras como la infraestructura. Además, se establece la importancia de las alianzas estratégicas y aprovechar incentivos gubernamentales para fortalecer la competitividad en un mercado en evolución. Esta investigación destaca como las prácticas de RSE mejoran no sólo la gestión de residuos, sino contribuyen a optimizar el bienestar social y económico de las comunidades locales. Finalmente, se concluye que, a pesar de las barreras regulatoria y tecnológicas existentes, las organizaciones que están comprometidas con prácticas de innovación y sostenibilidad.
Optimizing Logistics Operations: Identifying and Mitigating Risks through FMEA and Poka Yoke
Authors:   Master of Industrial Engineering, Islamic University of Indonesia, Yogyakarta, Indonesia, Yusri Ardhini Ramadhani , Immawan Taufiq ,   Master of Industrial Engineering, Islamic University of Indonesia, Yogyakarta, Indonesia
Published: January 2025

The logistics industry plays a crucial role in facilitating the smooth distribution of goods both nationally and internationally. With the growth of the transportation and warehousing sector contributing significantly to Indonesia’s GDP, logistics companies are increasingly vital in supporting trade activities. However, logistics companies face significant challenges, especially when shipping high-risk goods such as hazardous chemicals, which require careful handling due to their potential hazards to human health, safety, and the environment. In addition, maintaining service quality is essential to ensure consumer satisfaction, as delays, errors in documentation, and other issues can lead to dissatisfaction. PT XYZ, a logistics company in Indonesia, has encountered operational issues leading to delays in shipments, caused by factors such as bad weather, inconsistent schedules, and incomplete or inaccurate shipping documents. This study applies risk management techniques, specifically Failure Mode and Effect Analysis (FMEA) and Poka Yoke, to identify, assess, and mitigate risks in PT XYZ’s shipping operations. 15 risks are obtained with the most critical risk is inaccurate information about the goods being shipped, resulting in delays and financial losses. The Risk Priority Number (RPN) for this risk was calculated as 252, indicating a high severity and frequency of occurrence. To mitigate this risk, the study recommends implementing a Smart Logistic Checker system, which integrates automatic technologies such as barcode scanning, digital weighing, dimension measurement, and label printing, with automatic validation to ensure that the information matches the physical condition of the goods. This approach aims to reduce errors, enhance operational efficiency, and prevent failure.
Buccal Mucosa Graft for Cleft Palate Surgery
Authors:   MBChB, FICMS plastic, Specialist of Plastic and reconstructive surgery, Specialized Burn hospital, Medical City, Baghdad, Iraq., Mustafa Jawad Dr Talib , Dhumad Lami Dr Ali Haroon ,   FICMS, Specialist of Plastic Surgery, Specialized Burn hospital, Medical City, Baghdad, Iraq., Albakaa Dr Amir Abdul-Adhim ,   MBChB, FABMS plastic surgery, JMC plast, Specialist of Plastic and Reconstructive Surgery, Specialized Burn Hospital, Medical City, Baghdad. Iraq.
Published: January 2025

Background: Cleft palate repair aims at producing closure of the cleft with reasonable lengthy palate in order to have competent velopharyngeal closure. There are various procedures concentrate on the lengthening of the palate like: Veu Wardill and Kilner, Furlow double opposing Z-plasty, Mukherji bilateral mucosal cheek flap, and Kaplan unilateral mucosal cheek flap etc.

Buccal mucosal flap for nasal layer combined with Z-Plasty in the oral layer of the soft palate is one of these procedure provide reasonable length for cleft palate repair.

Objective: The aim of this study is to evaluate palatal lengthening by combination of unilateral retromolar buccal mucosal flap with Z-plasty and assessment of speech improvement.

Patients and methods: A prospective study of 22 patients of non-syndromic cleft palate underwent palatoplasty by unilateral retromolar buccal mucosal flap combined with Z-plasty of the mucous membrane of the oral layer in period from December 2008 to September 2009.

All patients evaluated regarding the type of the cleft by Veau’s classification, the length and the width of the cleft palate measured by using a ruler and the depth of eth nasopharynx (from the posterior margin of the soft palate to the posterior pharyngeal wall) also measured .

Result: The most common type of the cleft was unilateral cleft lip and palate (50%). The mean age at repair was 18 months. All patients developed acceptable palatal length intra-operatively; the gain in length was ranged from 1.7-2.5cm the mean was (2.2cm). One patients developed oronasal fistula at the junction of soft and hard palate was.

Conclusion: This technique was effective for lengthening the nasal as well as oral layer, also had advantage of achieving good muscular reconstruction.
Penanaman Nilai Islam Dalam Membentuk Self Efficacy Peserta Didik di UPT SMK Negeri 1 Nguling
Authors: Fitria Umami Nur , Agustin Maulid
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi peran penanaman nilai-nilai Islam dalam membentuk self-efficacy (kepercayaan diri) peserta didik di SMK Negeri 1 Nguling. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan studi kasus, yang melibatkan observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa kepercayaan diri memiliki pengaruh signifikan terhadap perkembangan akademik dan sosial peserta didik. Meskipun banyak peserta didik yang memiliki kemampuan akademis yang baik, mereka sering kali mengalami kekurangan dalam hal kepercayaan diri, yang dapat menghambat prestasi mereka. Penanaman nilai-nilai Islam dilakukan melalui berbagai kegiatan di sekolah, termasuk pengajaran berbasis nilai positif, sholat berjamaah, dan kegiatan sosial, yang terbukti meningkatkan kepercayaan diri, disiplin, dan keterampilan sosial peserta didik. Namun, penelitian ini juga mengidentifikasi beberapa faktor penghambat, seperti kurangnya pemahaman ajaran Islam dan pengaruh lingkungan negatif. Dukungan dari sekolah dan guru sangat penting dalam mendukung proses ini. Penelitian ini merekomendasikan penerapan program pelatihan yang berfokus pada pengembangan self-efficacy dalam konteks pendidikan Islam, serta pentingnya dukungan sosial dari guru, teman, dan keluarga. Dengan mengintegrasikan nilai-nilai aqidah, akhlak, dan ibadah dalam pembelajaran, diharapkan dapat membentuk pola perilaku positif dan menghasilkan pribadi Muslim yang berkualitas, baik secara jasmani maupun rohani.
The use of advocacy as a mechanism for improving patronage of polytechnic libraries in Rivers State, Nigeria
Authors: Saghanen-Ntogo Gideon B. , Carson Joy Anthony , Omachi Salifu Friday
Published: January 2025

The study investigated perception of librarians on the use of advocacy as a mechanism to improving patronage of Polytechnic Libraries in Rivers State, Nigeria. Survey research design was adopted for this study. The population for the study comprised of 60 library personnel from three polytechnic libraries in Rivers State. Census sampling techniques was used to select the entire population because it was manageable to handle. Questionnaire was used to collect data for this study. The data collected were presented and analyzed using mean and standard deviation. The study found out that the advocacy mechanisms used by librarians in polytechnic libraries in Rivers State to improving library patronage are not adequate. Library users revealed that only few advocacy mechanisms (library orientation, current awareness, library guides, library instructions, provision relevant information resources) used by librarians influence their patronage of the library. The study, therefore, recommended that librarians should employ different methods of advocacy such as marketing concepts, mass media, conducive environment, social media and information and communication facilities and resources like internet, etc., to advocate for greater library patronage
Librarians’ level of awareness of artificial intelligence as correlate of their digital competence at Joseph Sarwuan Tarka University Makurdi, Nigeria
Authors: Tor-Akwer Helen Famaren , Josiah Sarah Okpa , Asue Nguevese Elizabeth
Published: January 2025

This purpose of this paper is to investigate the level of awareness of AI among librarians at Joseph Sarwuan Tarka University, Nigeria, and explores its potential relationship with their digital competence. The study employed correlational design The population of the study comprised of 47 librarians’ from the Joseph Sarwuan Tarka University, Makurdi. The entire population was used as it was considered manageable. Artificial Intelligence Awareness Questionnaire (AIAQ) and Digital Competence Questionnaire (DCQ) were used for data collection with reliability indices of 0.93 and 0.87 respectively. The data collected were analyzed using mean and Pearson’s Product Moment Correlation (PPMC) statistics. The findings of this study revealed that there was moderate level of awareness of lecturers on AI, and also there was positive relationship between lecturers’ level of awareness of AI and their digital competence, among others. The study found a positive correlation between lecturers' awareness of Artificial Intelligence (AI) and their digital competence. It highlighted the need for targeted training programs to improve lecturers' digital skills and the potential benefits for students. The findings suggest that addressing AI awareness can enhance teaching, learning, and student success. The study recommended that school management should ensure organization of training programmes on AI to increase AI literacy and equip the librarians with the essential abilities to use AI effectively in their teaching activities.
IMPLEMENTASI KEBIJAKAN PERLINDUNGAN DAN PENATAAN PASAR TRADISIONAL PUSAT PERBELANJAAN DAN TOKO MODERN DI KABUPATEN BANGLI
Authors: Ariati Ni Kadek , Sedia I Wayan , Junaedy I Kadek Dede
Published: January 2025

Penelitian ini bertujuan untuk menganalisis implementasi kebijakan perlindungan dan penataan pasar tradisional, pusat perbelanjaan, dan toko modern di Kabupaten Bangli berdasarkan Peraturan Daerah (Perda) Nomor 1 Tahun 2016. Kebijakan ini dirancang untuk menjaga keseimbangan antara pasar tradisional dan pasar modern, serta mendorong keberlanjutan ekonomi lokal melalui pengaturan zonasi, pembatasan jumlah, waktu operasional, dan jarak minimal. Namun, hasil penelitian menunjukkan bahwa pelaksanaan kebijakan ini belum berjalan optimal. Pelanggaran aturan jarak minimal 500 meter antara pasar tradisional dan pasar modern menjadi salah satu permasalahan utama, yang berdampak pada penurunan daya saing pasar tradisional. Pasar modern menawarkan berbagai keunggulan seperti kenyamanan, promosi agresif, dan harga kompetitif, sehingga menarik minat konsumen dan menggeser preferensi belanja dari pasar tradisional.Selain itu, lemahnya pengawasan oleh pihak berwenang, seperti Satpol PP dan Dinas Perdagangan, serta kurangnya koordinasi antarinstansi, memperburuk situasi ini. Dampak negatif lain termasuk melemahnya keberlanjutan pasar tradisional yang sebagian besar diisi oleh pedagang kecil dan menengah, serta meningkatnya ketimpangan ekonomi. Dalam rangka meningkatkan daya saing pasar tradisional, penelitian ini merekomendasikan perbaikan kebijakan, termasuk revisi Perda, penguatan pengawasan, pemberian insentif bagi pedagang pasar tradisional, serta modernisasi fasilitas pasar. Langkah-langkah ini diharapkan dapat menciptakan keseimbangan antara pasar tradisional dan pasar modern, sehingga mendukung pertumbuhan ekonomi yang inklusif dan berkelanjutan di Kabupaten Bangli.
PENGARUH TOTAL ASSET TURNOVER (TATO), RETURN ON ASSET (ROA) DAN DEBT TO ASSET RATIO (DAR) TERHADAP PERTUMBUHAN LABA PADA PT. ADHI KARYA (PERSERO) TBK
Authors: Andriansyah Muhamad Rizki , Pratiwi Aliah
Published: January 2025

Abstrak – Penelitian ini bertujuan untuk mengetahu pengaruh Total Asset Turnover, Return On Asset dan Debt to Asset Ratio terhadap pertumbuhan laba Pada PT. Adhi Karya Persero Tbk. Instrumen penelitian ini yaitu menggunakan laporan keuangan di antara laporan neraca dan laba rugi pada PT. Adhi Karya Persero Tbk. Adapun data yang digunakan dalam instrumen penelitian ini yaitu data laba bersih, total penjualan, total hutang dan total aset dari tahun 2013-2022. Sedangkan teknik pengambilan sampel yang digunakan adalah purposive sampling. Kriterianya didasarkan pada ketersediaan data terupdate. Data dalam penelitian ini diolah menggunakan SPSS. Metode pengujian hipotesis menggunakan taraf signifikan 5%. Hasil penelitian menunjukan bahwa Total Asset Turnover (TATO) tidak berpengaruh signifikan terhadap pertumbuhan laba, Return On Asset (ROA) tidak berpengaruh signifikan terhadap pertumbuhan laba dan Debt to Asset Ratio (DAR)  tidak berpengaruh signifikan terhadap  pertumbuhan laba. Serta secara simultan Total Asset Turnover (TATO), Return On Asset (ROA) dan Debt to Asset Ratio (DAR) tidak berpengaruh terhadap pertumbuhan laba pada PT. Adhi karya Tbk
PENGARUH CONTENT MARKETING DAN CUSTOMER REVIEW TERHADAP KEPUTUSAN PEMBELIAN KONSUMEN DI MARKETPLACE TIKTOK SHOP (STUDI KASUS PADA MASYARAKAT KOTA BIMA)
Authors: Azhari A.Rahman , Ismunandar Ismunandar
Published: January 2025

Abstrak – Penelitian ini bertujuan untuk mengetahui pengaruh Content Marketing dan Customer Review terhadap Keputusan Pembelian konsumen di Marketplace TikTok Shop (Studi kasus pada Masyarakat Kota Bima). Metode penelitian yang digunakan dalam penelitian ini adalah metode survei dengan bentuk pernyataan tertulis melalui kuesioner sebanyak 96 responden sebagai sampel dalam penelitian ini. Analisis data menggunakan uji validitas, uji reabilitas, uji asumsi klasik (uji normalitias, uji multikolenearitas, uji heteroskedastisitas dan uji autokorelasi), analisis regresi berganda, koefisien korelasi, koefisien determinasi dan uji hipotesis (uji t dan uji F) melalui aplikasi perangkat lunak Statistical Product and Service Solution Ver.24 (SPSS). Hasil penelitian menunjukkan bahwa Content Marketing berpengaruh signifikan terhadap Keputusan Pembelian, Customer Review berpengaruh signifikan terhadap Keputusan Pembelian serta Content Marketing dan Customer Review berpengaruh signifikan terhadap Keputusan Pembelian. Kata kunci: Content Marketing, Customer Review, Keputusan Pembelian.
Application of IR Fourier microscopy for investigation of kimberlite indicator minerals to search for diamond deposits using heavy-mineral concentrate method
Authors: Khachatryan Galina , Anashkina Nataliya
Published: January 2025

Possibilities of the infrared microscopy technique as applied to the express diagnostics of diamond crystals and of grains of most of its satellite minerals, extracted from heavy mineral concentrate (HMC) samples, are considered. An original technique of investigation of the diamond satellite minerals
with IR-Fourier microscope has been developed. In this case, the spectrum of each sample is recorded, and its identification and determination of the characteristic wave numbers are performed automatically. These parameters are caused by peculiarities of the chemical composition and crystal structure of the mineral and allow one to conclude on its primary sources.
Typomorphic properties of kimberlite garnets, olivines, and clinopyroxenes and peculiarities of their IR spectra, that can be used for the prospecting and exploration purposes, are considered on specific examples. It is substantiated that application of the IR Fourier microscopy and of the developed electronic library of spectra of individual mineral grains contributes to increasing the efficiency of the analysis of panned HMC samples in forecasting of and exploration for diamond deposits
Determinar una nueva variable para el modelo predictivo de demanda, considerando la relación entre la cantidad de pasajeros de un terminal aéreo y la cantidad de habitantes de su área de influencia, caso Chile
Authors:   Universidad Andrés Bello, DEL VALLE Raul E.
Published: January 2025

Chile's economic development has boosted the internal demand for passengers at airport terminals, which has not always been matched by the supply of facilities, creating a mismatch between the size of the infrastructure of passenger terminals and the number of users. To solve this problem, it is necessary to review the variables to be used in estimating demand. This research obtains results by adding a new variable to the existing demand models.
Competencias tecnológicas en futuros docentes de zonas rurales: Un estudio en Puno, Perú
Authors:   Universidad César Vallejo, LAURA Eleuterio A. , SILVA Bertha ,   Universidad César Vallejo
Published: January 2025

The study evaluates the technological competencies of students at a higher pedagogical institute located in Puno. With a quantitative approach and a non-experimental design, 76 students were surveyed using a validated questionnaire. The results highlight strengths in technological literacy (62%) and collaborative communication (60%), but weaknesses in content creation (45%) and digital security (39%). It is recommended to strengthen these areas through pedagogical strategies adapted to the rural context.
Estudio teórico sobre Metodologías Activas en la educación básica
Authors:   Pontificia Universidad Católica del Ecuador, PORTERO Fanny B. , MEDINA Ricardo P. ,   Pontificia Universidad Católica del Ecuador
Published: January 2025

The article focuses on an education that marks the common good, considers individual and collective well-being, the objective is to analyze the active methodologies in basic education, a systematic review with PRISMA protocol and qualitative approach. 47 articles were obtained and active methodologies such as collaborative learning, project-based learning, gamification, flipped classroom and problem-based learning were found. It was concluded that active methodologies solve in real contexts and include technologies for students and teachers.
Procrastinación y rendimiento académico en el estudiantado de dos carreras universitarias en las áreas de Letras y Educación de la Universidad Nacional, Costa Rica
Authors:   Universidad Nacional, Costa Rica, RUIZ-CHAVES Warner
Published: January 2025

The study analyzed the relationship between procrastination and academic performance in Literature and Education students at the National University of Costa Rica. Using the PASS, procrastinated activities such as readings and non-evaluative tasks were identified, influenced by stress, expectations, and disorganization. Although both groups showed high academic performance, procrastination negatively impacted summative activities, increasing anxiety and stress levels. It is recommended to implement pedagogical strategies to enhance self-regulation, time management, and reduce academic stress.
Competencias lingüísticas en la comunicación escrita de estudiantes de Educación Básica Superior en Ecuador
Authors:   Universidad Estatal de Milagro, Ecuador, MOREIRA Maria F. , MONTERO Y. ,   Universidad Estatal de Milagro, Ecuador
Published: January 2025

The article titled "Linguistic Competencies in Written Communication of Upper Basic Education Students in Ecuador" addresses the issue of deficiencies in linguistic competencies in students from the educational institution Veinticuatro de Mayo, in Ecuador. The main objective of the study was to analyze the linguistic competencies in written communication of the 8th-grade Upper Basic Education (EBS) students, identifying their strengths and weaknesses in key areas such as spelling, punctuation, grammar, vocabulary, coherence, cohesion, and written production. Based on this diagnosis, innovative teaching strategies were proposed to improve student performance in these areas.
The specific objectives included diagnosing the difficulties and achievements in each of the evaluated dimensions, designing innovative didactic strategies that incorporated the use of digital technologies, collaborative learning, and text writing activities, and validating the effectiveness of these strategies through their application and feedback in an experimental group.
The methodology used was quantitative, with an experimental approach. Pre-implementation diagnostics were conducted, and the results revealed critical areas of improvement. In particular, Spelling and Punctuation was found to be the most deficient area, with 60% of students not meeting the basic standards, while Grammar and Vocabulary also presented significant issues for 43.33% of students. The implemented strategies, which included the use of technological tools and the promotion of collaborative practices, were key in improving linguistic competencies, especially in spelling and grammar, showing a significant improvement in student performance in these areas.
Mathematical Modeling and analysis of dynamics of Neisseria Gonorrhea Disease with Self Protection, Treatment and Natural Immunity
Authors: Ullah Irfan , Ahmad Imtiaz , Ali Nigar , Ahmad Zubair , . El Agamy Rasha F
Published: January 2025

We present a mathematical framework for the infection of Neisseria gonorrhea in this article. Compared to a number of earlier models in the literature, the new model is more comprehensive and covers a wide range of concepts. The local and global stability, sensitivity analysis, of the model are examined. The results are illustrated with algorithmic experiments. A computational analysis of the model is examined. highlighting the impact of different values of parameters on the model’s dynamics and offering potential avenues for further research. In this article, we present a robust mathematical framework for modeling the infection dynamics of Neisseria Gonorrhoea. Unlike earlier models in the literature, our approach is more comprehensive, integrating a wide array of concepts related to the infection process. We conduct an in-depth analysis of both local and global stability, along with a sensitivity analysis of the model parameters. The results are supported by algorithmic experiments that illustrate the model’s behavior under varying conditions. Additionally, we perform a thorough computational analysis, emphasizing how different parameter values influence the model’s dynamics. This work not only enhances our understanding of gonorrhea transmission but also identifies potential avenues for further research in this critical area of public health. Keywords: Neisseria Gonorrhea, Stability analysis, Numerical simulation, Sensitivity analysis
Control of Marburg Virus Disease Spread in Humans under Hypersensitive Response through Fractal-Fractional
Authors: Faiz Khurram , Ahmad Aqeel , Khan Muhammad Suleman , Abbas Safdar
Published: January 2025

The primary objective of this research is to examine the model of Marburg virus disease with therapy to prevent the infections from spreading throughout the community due to saliva, urine, and feces. A mathematical model is established using the created hypothesis for a healthy environment in order to examine the different rates of Marburg virus disease after taking control measures with treatment for different protection. The model is then converted into a fractional ordered model for continuous monitoring, including theoretical solutions, by using the Fractal Fractional operator. The model’s global stability is studied through Lyapunov derivative by equilibrium and endemic point of model. Both qualitative and quantitative analysis is done on a proposed model with the power law kernel, with particular focus on unique solutions, positivity, and boundedness. By using of fixed point theory and the Lipschitz condition, there is only one exact solution. By confirming the Lyapunov function globally, equilibrium points that are both endemic and disease-free are checked for stability. Numerical simulations are utilized to investigate the effects of the fractal fractional operator on the generalized form of the power law kernel using a two-step Lagrange polynomial approach for ongoing monitoring of the Marburg virus disease and treatment strategies. The simulations show how different parameters affect the illness. In order to simulate the actual behavior and management of Marburg virus disease produced by saliva, urine, and feces and to implement control measures for a healthy environment with a hypersensitive reaction (HR), simulations have been constructed. This type of research will be helpful in figuring out how diseases spread and in developing management strategies based on our verified results for human in community.