bluuebunny/crossref_metadata_2025 huggingface dataset:
Reverse Engineering in the Manufacturing of Lorry Wheels in Palm Oil Processing
Authors: Mahmud Mahmud , Zulfadli Zulfadli , Hamdani Hamdani , Azwar  , Sariyusda
Published: February 2025

The reverse engineering process in development is widely used to carry out the reverse engineering process for the design of certain products, in this study the reverse engineering process on the palm oil lorry wheel is to improve the design as well as a combination of materials to increase the life of the lorry wheel product in the palm oil processing. The process of scanning the surface of the lorry wheel using camera and the reverse engineering process is carried out by measuring the precision of the lorry wheel by measuring using a precision measuring instrument, data obtained by measurement and reconstruction model. data obtained by measurement and reconstruction model using CAD software and CAE software used to analyze the CAD and CAE software are used to analyze the design results after the reverse engineering process. reverse engineering process.  So, it is necessary to develop a reverse engineering system design that will be useful in terms of efficiency and service life of the lorry wheel, in the design of this lorry wheel uses CAD and CAM software to model the lorry wheels with simulation and analysis systems. The next process is to modify and remanufacture the lorry wheel model using machine tools so that the prototype of the manufacturing process can be tested. so that the prototype of the manufacturing process can be tested on the lorry to see the durability of the reverse engineering product. to see the durability of the reverse engineering product. The results of this research showed that the reverse engineering data can be interpolated for further CAE process
Measuring Quality Change in the Market for Anti-Ulcer Drugs
Authors: Haider Rehan
Published: February 2025

The General Accounting Office released a study in August 1992 of twenty-nine sampled prescription drugs that reported an average increase in the price of approximately 138 percent between 1985 and 1991 (GAO 1992, 4, table 1) Those and other published price indexes are increasingly being used in the public policy arena to focus the debate on the potential regulation of pharmaceutical prices and the coverage of health insurance. In an industry where products are multidimensional and the rate of technological progress is brisk, misinterpretation of unadjusted indices of drug prices can easily arise. This can lead to erroneous conclusions regarding appropriate policies for the pharmaceutical industry. Researchers have addressed numerous general theoretical issues concerning the construction and interpretation of price indices (Fisher and Shell 1983) [1]. Two issues of particular interest for pharmaceutical markets are the new goods problem, which deals with the introduction of generic drugs into a drug price index, and the quality problem, which recognizes that newer versions of drugs with the same basic Chemical action may be superior in certain dimensions to drugs already on the market. Specific to pharmaceutical markets, Berndt et al., (1993) [2] have also argued that the sampling procedure used by the Bureau of Labor Statistics to calculate pharmaceutical price indices is flawed. Each of those problems deserves careful analysis. This study focuses on the issue of product quality measurement and quality change.
Post-traumatic extensive chronic osteomyelitis of skull vault: An illustrative case report
Authors: Reshtin Maksalmina
Published: February 2025

Chronic osteomyelitis of the skull base is a commonly reported pathology in existing scientific literature, but chronic osteomyelitis of the skull vault (COSV) is a rarely documented disease. We report the case of a 38 years old Afghan male with a presenting complaint of irregular swelling on the skull vault for six months. The patient had a history of head trauma one year back with a compound depressed fracture which had been surgically managed then. Physical examination revealed a 15 x 15 cm hard, immobile swelling with an old scar mark over the scalp. Neuroimaging was consistent with diffuse, bilateral frontoparietal swelling of bony origin, sparing underlying brain parenchyma. Surgically excision of the lesion was done through a bicoronal skin flap and cranioplasty done at the same time. Histological findings of the specimen reported chronic osteomyelitis. However, microbiology revealed no growth in culture. Patient was discharged on the second postoperative day uneventfully. This case turns minds into keeping skull vault osteomyelitis as differential diagnosis besides other spontaneous bony lesions; e.g. fibrous dysplasia, osteoma and giant cell tumours.
Aplicación de un proceso electroquímico para tratar residuos líquidos de pruebas de tinción de GRAM
Authors:   Escuela de Ingeniería Ambiental, Universidad de Ciencias y Artes de Chiapas, Tuxtla Gutiérrez Chiapas, México, Celia Fabiola de Jesús Velasco-Ortiz , Carlos Enrique López-Aguilar ,   Escuela de Ingeniería Ambiental, Universidad de Ciencias y Artes de Chiapas, Tuxtla Gutiérrez Chiapas, México, Hugo Alejandro Nájera-Aguilar ,   Escuela de Ingeniería Ambiental, Universidad de Ciencias y Artes de Chiapas, Tuxtla Gutiérrez Chiapas, México, Rubén Fernando Gutiérrez-Hernández ,   Tecnológico Nacional de México, Instituto Tecnológico de Tapachula, Depto. De Ingeniería Química y Bioquímica, Tapachula, Chiapas, México, Juan Antonio Araiza-Aguilar ,   Escuela de Ingeniería Ambiental, Universidad de Ciencias y Artes de Chiapas, Tuxtla Gutiérrez Chiapas, México
Published: February 2025

Las actividades experimentales propias de laboratorios de docencia o inves-tigación en instituciones de educación superior, puede conducir a la generación de aguas residuales complejas de tratar por su alta carga orgánica y baja biodegradabilidad, como las provenientes de las pruebas de tinción de Gram (agua residual compuesta por la mezcla de distintos colorantes como naranja de metilo, azul de metileno y violeta de genciana, entre otros). Para el tratamiento de estos efluentes, los Procesos Avanzados de Oxidación (PAO) llegan a ser una buena opción al poder alcanzar la mineralización completa de los contaminantes, como es el caso de la Oxidación Anódica (OA). Así, la efectividad de la OA fue probada usando dos tipos de elec-trodos; grafito como cátodo, y Diamante Dopado con Boro (DDB) como ánodo. La eficiencia del proceso fue ensayada siguiendo el comportamiento de la Demanda Química de Oxígeno (DQO) y del color como variables de respuesta. Los ensayos se hicieron bajo un diseño experimental 32, esto es, distintas intensidades de corriente (0.10, 0.20 y 0.30 A) y valores de pH (3, 5 y 7). El influente, partió de concentraciones iniciales en DQO y Color de 623 mg/L y 234 Pt-Co, respectivamente, y de los tratamientos ensayados, el mejor de ellos se tuvo a pH 7 y 0.30 A, con remociones del 100% en ambos parámetros, y hasta 96.7% en los sólidos suspendidos, para un tiempo de reacción de 90 minutos. De esta manera, la OA demostró ser eficiente para oxidar los contaminantes presentes en residuos líquidos provenientes de las pruebas de tinción de Gram, por lo que puede ser una opción real de tratamiento para esta mezcla compleja de residuos de colorantes generados en ambientes escolares.
Aspiring to a Normal Life
Authors: Schultz Ulrike
Published: February 2025

Sudan since its independence in 1956 and South Sudan since its secession from Sudan in 2011 have been exposed to political and economic crises, civil wars, and local and regional outbreaks of violence that have forced people to leave their homes and move on to more secure places. Reflecting on the lives of two women, I scrutinize how people try to live normal lives despite the chronicity of crisis and a high degree of (forced) mobility. For them, mobility is an essential part of their livelihood and helps to create lives that are “meaningful, reasonable, and normal.” Furthermore, I reflect on the aspiration/ability model and ask how the wish to live normal lives leads to migration on the one side and forced (im)mobility on the other.
Measuring Dropout Intention in First Year University Students
Authors: Cazan A.M. , Truta C. , Stan M.M. , Maican C.I. , Stoica R.E.
Published: February 2025

University dropout has become an increasingly critical research topic, particularly in the wake of the COVID-19 pandemic, which has seen a global rise in dropout rates. This phenomenon, defined as the discontinuation of higher education before degree completion, is multifaceted, with psychological, sociological, institutional, and interactionist perspectives offering diverse insights into its causes. Despite extensive research dating back to the 1980s, there is a notable lack of standardized instruments for measuring dropout intentions, particularly in the Romanian context. This study addresses this gap by proposing and evaluating the psychometric properties of a concise, five-item scale designed to assess dropout intentions among university students. The scale demonstrated strong internal consistency and construct validity through exploratory and confirmatory factor analyses. Additionally, measurement invariance across gender was confirmed, though the results highlight the importance of a more diverse sample in future research. The findings underscore the need for robust, theoretically grounded instruments to facilitate early detection of dropout intentions and inform targeted interventions.
Objectification and Physical Appearance in Adolescent Girls
Authors: David L.T. , David T.
Published: February 2025

Objectification, understood as internalization of an external observer's perspective of their own bodies, is a phenomenon experienced by females. The present research focuses on examining the relationships among sexual objectification, body shame, body appearance anxiety, fear of negative evaluation, and eating attitudes in dancer and non-dancer adolescents. The results revealed no significant differences between the two groups. However, sexual objectification was found to be associated with body shame, eating attitudes, and fear of negative evaluation.
PENGARUH BEBAN PAJAK, PROFITABILITAS DAN UKURAN PERUSAHAAN TERHADAP TRANSFER PRICING DIMODERASI OLEH MEKANISME BONUS
Authors: Fhasli Hanifan Maha Putra Muhammad Adam
Published: February 2025

Perkembangan ekonomi digital telah mengubah dinamika operasional perusahaan multinasional (MNEs) dan menciptakan tantangan baru dalam analisis Transfer pricing. Penelitian ini bertujuan untuk mengeksplorasi pengaruh beban pajak, profitabilitas, dan ukuran perusahaan terhadap praktik Transfer pricing, dengan mekanisme bonus sebagai variabel moderasi. Fokus penelitian adalah pada perusahaan pertambangan yang terdaftar di Bursa Efek Indonesia selama periode 2018-2022. Metodologi yang digunakan adalah penelitian eksplanatori dengan analisis kuantitatif melalui regresi logistik dan analisis regresi moderasi menggunakan software SPSS versi 23. Data sekunder yang dikumpulkan mencakup laporan keuangan dan penelitian sebelumnya, dengan populasi 63 perusahaan dan sampel akhir sebanyak 44 perusahaan setelah menerapkan purposive sampling. Hasil penelitian menunjukkan bahwa beban pajak dan profitabilitas berpengaruh signifikan terhadap Transfer pricing, sementara ukuran perusahaan tidak berpengaruh signifikan. Mekanisme bonus terbukti memoderasi pengaruh profitabilitas dan ukuran perusahaan terhadap Transfer pricing, tetapi tidak memperkuat pengaruh beban pajak.
Analysis of Number Material in Seventh-Grade Mathematics Teaching Materials Based on Praxeology
Authors: Putri Astiwi Comastika , Sujadi Imam , Laila  Fitriana
Published: February 2025

Ketersediaan buku teks matematika yang tidak sesuai dapat mempengaruhi rendahnya kinerja akademik siswa. Penelitian ini bertujuan untuk menganalisis bahan ajar matematika sekolah dari perspektif praxeologis, di mana peneliti berusaha memahami bagaimana siswa berinteraksi dengan materi yang disajikan dalam bahan ajar, bagaimana mereka membuat keputusan tentang masalah mana yang akan diselesaikan, dan bagaimana desain serta konten buku teks mempengaruhi hasil belajar mereka. Ini adalah implementasi paradigma interpretatif dalam penelitian desain didaktik. (DDR). Melalui studi dokumen (dalam penelitian kualitatif yang dirancang secara fenomenologis) pada bahan ajar matematika sekolah Indonesia versi Kurikulum Merdeka, hasil yang diperoleh adalah: Komponen tugas (T) dalam materi tentang bilangan besar menggunakan teknik operasional; Komponen teknik (τ) sesuai karena informasi yang disampaikan dalam setiap pertemuan memiliki kontinuitas; Komponen teknologi (θ) belum sesuai, sehingga perbaikan dan peningkatan diperlukan dalam pengembangan media pembelajaran berbasis teknologi informasi dan komunikasi; dan Komponen teori (Θ) belum sepenuhnya selaras dengan teori konstruktivis, di mana siswa dapat membangun pengetahuan berdasarkan pengalaman masing-masing.The availability of mathematics textbooks that are not appropriate can influence students' low academic performance. This research aims to analyze school mathematics teaching materials from a praxeological perspective, where the researcher seeks to understand how students engage with the material presented in the teaching materials, how they make decisions about which problems to solve, and how the design and content of textbooks affect their learning outcomes. This implements the interpretive paradigm in didactical design research (DDR). This study will involve three principal stages in the data analysis procedure. Through document studies (in phenomenologically designed qualitative research) on the Indonesian school mathematics teaching materials version of the Merdeka Curriculum, the results obtained are: The task component (T) in the material on large numbers uses operational techniques; The technique component (τ) is appropriate because the information conveyed in each meeting has continuity; The technology component (θ) is not yet appropriate, so improvements and enhancements are needed in the development of information and communication technology-based learning media; and The theory component (Θ) is not yet fully aligned with constructivist theory, where students can build knowledge based on their respective experiences. The praxeological study of this teaching module provides a new perspective on how task design plays an important role in making the presentation of material more acceptable to students.
The Secret to Effective Learning: The Magic of Formative Assessment in Mathematics Class
Authors: Lele Marten Luter Ke , Marsigit Marsigit , Retnawati Heri
Published: February 2025

Penelitian ini dilakukan untuk menentukan efektivitas penilaian formatif dalam pendidikan Matematika melalui metode tinjauan pustaka. Metode penelitian yang digunakan adalah studi literatur meliputi buku, tesis, disertasi, artikel, dan sumber lain yang relevan. Data dianalisis menggunakan teknik analisis integratif. Hasil penelitian menunjukkan bahwa penilaian formatif sangat penting karena memberikan pemahaman yang lebih mendalam tentang kekuatan dan kelemahan siswa dalam menguasai konsep-konsep matematika. Hal ini memungkinkan guru untuk melakukan penyesuaian strategi pengajaran secara real-time guna mendukung pemahaman siswa secara optimal. Dalam pendidikan Matematika, penilaian formatif diidentifikasi sebagai katalis yang sangat penting dalam menyediakan pengalaman belajar yang lebih mendalam dan bermakna bagi siswa. Penilaian formatif sangat efektif dalam pendidikan Matematika, membantu guru memahami sejauh mana siswa telah menguasai materi yang diajarkan, mengidentifikasi area yang memerlukan perbaikan, dan menyesuaikan pengajaran untuk memenuhi kebutuhan siswa. Selain itu, penilaian formatif lebih efektif dibandingkan penilaian sumatif dalam hal meningkatkan motivasi akademik, mengurangi kecemasan terhadap ujian, dan meningkatkan keterampilan regulasi diri.Mathematics education through the literature review method. The research method used is literature study including books, theses, dissertations, articles and other relevant sources. Data were analyzed using integrative analysis techniques. The research results show that formative assessment is very important because it provides a deeper understanding of students' strengths and weaknesses in mastering mathematical concepts. This allows teachers to adjust teaching strategies in real-time to optimally support student understanding. In Mathematics education, formative assessment is identified as a very important catalyst in providing deeper and more meaningful learning experiences for students. Formative assessment is very effective in Mathematics education, helping teachers understand the extent to which students have mastered the material being taught, identify areas that need improvement, and adapt instruction to meet students' needs. In addition, formative assessment is more effective than summative assessment in terms of increasing academic motivation, reducing test anxiety, and improving self-regulation skills.
Trivium Curriculum in Traditional Game Based-Learning Construction
Authors: Hariastuti Rachmaniah Mirza , Amin Siti Maghfirotun , Utami Niken Wahyu
Published: February 2025

Penelitian ini bertujuan untuk mengeksplorasi dan mengidentifikasi etnomatematika dalam permainan kuartet Using, serta menerapkan kurikulum trivium berbasis permainan tersebut dalam pembelajaran materi statistika di Sekolah Dasar kelas 3. Eksplorasi dan identifikasi etnomatematika dilakukan dalam kerangka penelitian kualitatif. Pengumpulan data dilakukan dengan wawancara, observasi, dan dokumentasi. Analisis data dilakukan secara kualitatif. Data menunjukkan permainan kuartet Using memuat konsep membilang, himpunan, perbandingan, relasi, fungsi, persegipanjang, sudut siku-siku, hubungan antar garis, kekongruenan, peluang, dan statistika. Selain itu terdapat aktivitas berhitung, bermain, dan menjelaskan dalam permainan kuartet Using. Kurikulum Trivium diterapkan dalam pembelajaran pada Sekolah Dasar kelas 3 dengan responden sebanyak 19 siswa. Pengumpulan data dilakukan dengan observasi dan tes tertulis, sedangkan analisis data dilakukan secara kualitatif dengan menentukan persentase ketercapaian konsep. Implementasi dalam pembelajaran menunjukkan bahwa pencapaian konsep literacy dan technoracy hanya 78,95%, sedangkan konsep matheracy mencapai 94,74%. Artinya implementasi kurikulum trivium dalam pembelajaran belum optimal. Hal ini terjadi karena masih ada siswa yang belum bisa membaca dan menulis dengan baik.This study aims to explore and identify ethnomathematics in the Using quartet game, as well as apply the game-based trivium curriculum in learning statistics material in grade 3 elementary schools. The exploration and identification of ethnomathematics was carried out within a qualitative research framework. Data were collected through interviews, observation and documentation. Data analysis was done qualitatively. The data shows that the Using quartet game contains the concepts of counting, sets, comparisons, relationships, functions, rectangles, right angles, relationships between lines, congruence, opportunities, and statistics. In addition, there are counting, playing, and explaining activities in the Using quartet game. Trivium curriculum was applied in learning at grade 3 elementary school with 19 students as respondents. Data collection was done by observation and written test, while data analysis was done qualitatively by determining the percentage of concept achievement. Implementation in learning shows that the achievement of literacy and technoracy concepts is only 78.95%, while the concept of matheracy reaches 94.74%. This means that the implementation of the trivium curriculum in learning is not optimal. This happens because there are still students who cannot read and write well.
Feasibility of Opportunity Material Module with Joymath Cognitive Behavioral Method to Reduce Mathematics Anxiety and Increase Student Self-Efficacy
Authors: Marhaeni Nafida Hetty , Khuzaini Nanang , Rizky Muhammad Rafi Fajar , Yuniasanti Reny , Akbar Mutaqin , Sari Dian Kartika , Dangin Dangin
Published: February 2025

Siswa memerlukan media pembelajaran yang dapat membantu siswa mengurangi kecemasan matematika dan meningkatkan efikasi diri. Tujuan penelitian yaitu mengembangkan modul untuk mengurangi kecemasan matematika dan meningkatkan efikasi diri siswa pada materi peluang. Penelitian Research and Development ini menggunakan model ADDIE dengan lima tahap pengembangan yaitu analisis, desain, pengembangan, implementasi, dan evaluasi. Sumber data dan subjek dalam penelitian ini adalah ahli materi, ahli media, guru, dan 1328 siswa dari 24 SMP di Kota Yogyakarta. Teknik pengumpulan data yang digunakan yaitu wawancara, observasi, Focus Group Discussion (FGD), dan angket. Hasil menunjukkan bahwa produk yang dikembangkan yaitu modul materi peluang untuk mengurangi kecemasan matematis dan meningkatkan efikasi diri siswa layak digunakan dalam pembelajaran matematika. Pengambilan keputusan kelayakan produk didasarkan pada hasil analisis penilaian dari validator, ahli materi, dan ahli media yang menunjukkan bahwa modul sangat valid dan berpeluang menurunkan kecemasan matematis dan meningkatkan efikasi diri siswa.Students need learning media that can help students reduce mathematics anxiety and increase self-efficacy. The aim of the research is to develop a module to reduce mathematics anxiety and increase students' self-efficacy in opportunity material. This Research and Development research uses the ADDIE model with five development stages, namely analysis, design, development, implementation and evaluation. The data sources and subjects in this research were material experts, media experts, teachers, and 1328 students from 24 junior high schools in Yogyakarta City. The data collection techniques used were interviews, observation, Focus Group Discussion (FGD), and questionnaires. The results show that the product developed, namely the opportunity material module to reduce mathematical anxiety and increase students' self-efficacy, is suitable for use in mathematics learning. Decision making on product feasibility is based on the results of assessment analysis from validators, material experts and media experts which show that the module is very valid and has the opportunity to reduce mathematical anxiety and increase student self-efficacy.
Sacroiliitis associated with isotretinoin use: a clinical case and literature review
Authors: Dzhus Marta , Mulyk Kateryna , Potomka Ruslana , Aitul Elizaveta
Published: February 2025

Isotretinoin is an effective treatment for severe forms of acne vulgaris; however, its use may be accompanied by rare side effects involving the musculoskeletal system, including sacroiliitis. This article presents a clinical case of bilateral sacroiliitis induced by isotretinoin in an HLA-B27-positive patient. A literature review is provided regarding the frequency of this complication, its pathophysiological mechanisms, disease progression, and remission duration after discontinuation of the drug. The role of immunological factors, including the cytokine balance, matrix metalloproteinase (MMP) activity, as well as genetic factors (HLA-B27), in the development of joint lesions during isotretinoin therapy is discussed. It is determined that sacroiliitis most commonly occurs in the first months of treatment, usually resolves after discontinuation of the drug, but in some cases may become chronic, requiring prolonged therapy with nonsteroidal anti-inflammatory drugs or other medications. The analysis of the data emphasizes the importance of an interdisciplinary approach in managing patients receiving systemic retinoids, especially those with genetic predisposition, for timely diagnosis and treatment optimization.
Surgery in the Conditions of Globalized Pandemics
Authors: Bilodid Vladyslav , Rebedailo Kateryna
Published: February 2025

the article is devoted to the study of surgery in the conditions of globalized pandemics. The purpose of the article is a systematic review of professional works within the analysis of key aspects related to the discussion of the organization of surgical care, the safety of patients and medical personnel, as well as the adaptation of medical practices to the needs of surgery in the conditions of globalized pandemics. The task is to determine the key aspects that are not fully disclosed in modern professional works covering the issue of the development of surgery in the conditions of globalized pandemics. On the basis of a generalized solution to the task at a comprehensive level, modern works devoted to the coverage of issues related to the development of surgical practice in the conditions of globalized pandemics were analyzed. To determine the current state of research on the adaptation of surgical cases in the conditions of globalized pandemics, a comprehensive analysis of professional publications was conducted in various databases, in particular in Google Scholar, PubMed, Scopus and IEEE Xplore. After a complex of professional sources, the discovered data were subjected to operational systematization, which was aimed at determining the main aspects that are not fully covered in the reviewed papers. Conclusions: In general, the analysis of scientific works showed that: 1. Globalized pandemics have become powerful catalysts for changes in surgical practice; 2. Surgeons around the world are forced to adapt quickly to new realities, implementing new preventive measures, changing surgical procedures and managing resources; 3. Learning from the lessons learned during these pandemics is critical to preparing for future global crises and ensuring health system resilience. 4. In modern professional works on the raised issue, there are a number of shortcomings, as a result of which the peculiarities of surgical practice in the conditions of globalized pandemics are not fully revealed.
Tendinous part of the diaphragm under the influence of carboxyperitoneum and simulated jaundice: an experimental study
Authors: Dovhyy Bohdan , Kritsak Myroslav
Published: February 2025

understanding the increase in intra-abdominal pressure during pneumoperitoneum due to carbon dioxide insufflation as part of laparoscopic surgery is important as systemic changes due to carbon dioxide have become important. Despite the benefits, laparoscopic surgical procedures and insufflation affect many systems and organs, such as the brain, lungs, and liver. The aim of the study was to investigate the histological structure of the tendon parts of the diaphragms of rats with obstructive jaundice under the influence of standard pneumoperitoneum pressure formed by carbon dioxide, which is used in laparoscopic surgery, for a variety of time periods. The experimental study was performed on 70 mature rats weighing (235.0±20.0) grams. Obstructive jaundice was modelled by ligation of the common bile duct through a previously made laparotomy access. Pneumoperitoneum was created after puncture of the abdominal wall with a Veresch needle connected to an insufflator that injected carbon dioxide and maintained a given intra-abdominal pressure for a certain time. Obstructive jaundice led to thickening of the tendon due to edema. Collagen fibres acquired a tortuous direction. The cellular infiltration was distinct, with macrophages appearing in the structure. In 1 hour after pneumoperitoneum, there was an undulating direction of collagen fibres separated by intercellular substance, in which fibroblasts, lymphocytes and multiple macrophages were visualised. After 2 hours, there was a thickening of collagen fibres, homogeneity with multiple foci of decay and delimitation by the main substance containing fibroblasts and macrophages. After 3 hours, in addition to the disintegration, loss of unidirectional arrangement, in some cases, foci of chaotic accumulation of cell-fibre mass and haemorrhages were detected. In cellular infiltrates, plasmacytes appeared in small numbers among lymphocytes. The results obtained indicate that obstructive jaundice leads to structural changes in the tendon part of the diaphragm. Pneumoperitoneum with carbon dioxide exacerbates the changes in the morphological picture, which depend on the duration of the latter.
The Role of Aldosterone in the Development of Chronic Kidney Disease in Individuals with Type 2 Diabetes
Authors: Yerokhovych Viktoriia , Tahiieva Nazrin , Komisarenko Iuliia
Published: February 2025

modern statistics confirm that diabetes has become an epidemic of the 21st century. According to the forecasts of the International Diabetes Federation, by 2045, the number of people with diabetes is expected to reach 784 million. Approximately 90% of cases involve type 2 diabetes, which is a major contributor to the development of chronic kidney and cardiovascular diseases. The role of aldosterone in the progression of persistent kidney filtration rate disorders is particularly important due to the high prevalence of microvascular complications in individuals with type 2 diabetes, especially diabetic nephropathy. The activation of the renin-angiotensin-aldosterone system, alongside inflammatory processes, fibrotic changes in the kidneys, endothelial dysfunction, and disturbances in carbohydrate metabolism, are key pathogenetic factors in the development and progression of cardio-renal-metabolic syndrome. This syndrome, officially recognized by the American Heart Association, encompasses chronic kidney disease, which significantly worsens the clinical condition and prognosis of individuals with type 2 diabetes. Understanding the relationship between aldosterone levels and irreversible changes in kidney filtration rate in patients with type 2 diabetes is essential for exploring the mechanisms of the renin-angiotensin-aldosterone system's impact on kidney function in diabetic nephropathy. This study analyzed a range of parameters, including age, anthropometric indicators, carbohydrate metabolism, physical data, aldosterone levels, vitamin D (25OH) levels, and the albumin-to-creatinine ratio in daily urine. Participants were grouped according to their glomerular filtration rate, with a rate of <60 ml/min/1.73 m² indicating persistent pathological changes in the kidneys among individuals with type 2 diabetes. The results revealed a negative correlation between aldosterone levels and glomerular filtration rate in individuals with persistent kidney changes caused by diabetic nephropathy. These changes serve as risk factors for cardiovascular diseases. Elevated aldosterone levels, albuminuria, decreased glomerular filtration rate, and reduced vitamin D (25OH) levels were identified as early indicators of chronic kidney disease in individuals with type 2 diabetes.
Exploring the track of Forensic Serology: A 23-Year Bibliometric Analysis
Authors: Pujari Avinash J.
Published: February 2025

this bibliometric evaluation reviewed forensic serology studies from 2000 to 2023, utilising Scopus records to song guide trends, key contributors, and impactful research. The subject showed significant growth, with 201 documents posted at a four.89% annual boom price. Major members consist of Virginia Commonwealth University and fantastic researchers like Hanson EK and Juusola J. The studies highlight diverse file kinds and influential papers, emphasizing ongoing advancements and the want for global collaboration. Limitations encompass reliance on Scopus and ability language bias. Overall, the study demonstrates the dynamic progress in forensic serology and the significance of continued research.
Efektifitas beberapa tumbuhan air untuk meningkatkan kualitas limbah cair industri tahu pada pabrik tahu podomoro Desa Sebidai Kecamatan Sesayap Kab. Tana Tidung
Authors: Esrahwati Esrahwati , Riani Etty , Nurmawati Subekti
Published: February 2025

Industri tahu adalah industri yang menghasilkan  limbah  cair  yang  mengandung  senyawa  organik  dan  anorganik, sehingga  berdampak  negatif  terhadap  lingkungan  dan  masyarakat  sekitar.  Upaya  untuk  mengatasi pencemaran   akibat   limbah   dilakukan   dengan   cara   fitoremediasi   menggunakan   berbagai macam tanaman air. Tujuan penelitian ini adalah Untuk menganalisis uji penurunan kadar pencemar air limbah tahu ditinjau dari parameter BOD, COD, TSS, suhu dan pH menggunakan metode fitoremediasi dengan memanfaatkan tanaman air (eceng gondok, kangkung air, dan ganggang), menganalisis perbandingan efektifitas fitoremediasi dari tiga tanaman air (eceng gondok, kangkung air dan ganggang) dalam menurunkan kadar pencemar air limbah tahu (BOD, COD ,TSS, suhu dan pH) dan menganalisis pengaruh konsentrasi limbah terhadap penurunan kadar pencemar limbah dalam meningkatkan kualitas air limbah, dengan konsentrasi limbah pada fitoremediasi. Penelitian menggunakan Rancangan Acak Kelompok, dengan perlakuan jenis tanaman air (T) yaitu eceng gondok, ganggang, dan kangkung serta konsentrasi air limbah tahu (L).  Parameter penelitian adalah: BOD, COD, TSS, pH, dan suhu. Hasil penelitian jenis tanaman air yang memiliki efektivitas paling tinggi dalam menurukan kadar cemaran limbah (BOD, COD, dan TSS) adalah tanaman ganggang. Pada perlakuan konsentrasi limbah, diperoleh hasil bahwa semakin tinggi konsentrasi limbah tahu yang digunakan, maka efektivitas penurunan cemaran limbah akan semakin kecil.
Rising Above the Challenge : The Underutilization of Data Analysts and Engineers
Authors: Deepak Chanda
Published: February 2025

Unfortunately, this often means that data analysts and data engineers are underutilized in many organizations — their skills go largely untapped trying to solve strategic business challenges. However, they often note inefficiencies and take the lead on innovation. This article deploys a real-world case study to investigate the phenomenon, exploring how a data-professional at a company, went above and beyond to secure meaningful transformation to the organization.
Parkinson’s Disease Detection Using Machine Learning
Authors: CH. Lalitha Haripriya  , CH. Sirisha  , A. Gnaneswar  , K. Nagendra  , Dr. R. Rajender
Published: February 2025

Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting movement and motor control. Early detection is crucial for effective treatment and management. This paper presents a machine learning-based approach to detect Parkinson’s disease using speech and biomedical data. The proposed model utilizes various machine learning algorithms, including Support Vector Machines (SVM), Random Forest, and Deep Learning techniques, to classify PD and non-PD subjects. The model is trained on a publicly available dataset and achieves significant accuracy in classification. Multi-modal analysis enhances diagnostic accuracy, offering a non-invasive, cost-effective solution. Future work will focus on real-time monitoring, expanding datasets, integrating wearable technology, and improving model interpretability for clinical applications.
Ethics and Governance of Health Research Data in International Organizations: A Framework Analysis
Authors: Cheng Qing
Published: February 2025

Taking the relevant policies of health research data issued by international organizations as the research object, using the life cycle theory, this paper constructs an international ethics governance framework for health research data from the perspectives of governance stages and means. It summarizes the connotation, means, and policy focus of international organizations' ethics governance for health research data. This paper aims to provide references for countries worldwide to optimize the ethics governance of health-related research data, improve the governance level of health research data, and foster a robust ecosystem for data opening and sharing.
Analysis of Inside Controls Risks in Public Hospitals under Public Health Emergencies and Study on Countermeasures
Authors: Lin Tingting , Wu Bin , Chen Zhiyuan , Zhu Junsun , Ye Wencheng
Published: February 2025

With the rapid development of social economy and the increase of population mobility, the frequency and scope of influence of public health emergencies are also expanding. Under such a background, as the main force to deal with public health emergencies, the inside control risk of public hospitals has become increasingly prominent. This paper aims to discuss how to strengthen inside controls in public hospitals under public health emergencies, reduce risks, and ensure the stability and safety of hospital operation.
Complete Intrasubstance Long Head Biceps Brachii Rupture with Successful Repair: A Case Report
Authors: Wu Zifeng , Liao Hengyu , Huang Zhiyu , Li Jieruo
Published: February 2025

Intrasubstance biceps rupture is a rare injury. Closed traumatic biceps rupture is a relatively rare injury, and although an intramuscular tear, appropriate surgical timing and technique can be well treated. We report a case of traumatic abdominal Intrasubstance biceps rupture, mainly repaired by using a modified Mason-Allen (allograft tendon augmentation) technique. After 6-month follow-up, physical strength and good repair, clinical and MRI examination. The DASH score showed 0 out of 100 (no disability). Application of this technique can successfully repair acute traumatic closed biceps cross section, with good postoperative function.
Recurrence of Chyluria after Surgery: Erythromycin Solution Sclerotherapy and a Review of Literature
Authors: Xu Ao , Li Xiang , Zou Jinhan , Ruan Shuai , Guo Xi
Published: February 2025

Chyluria refers to the appearance of milky white urine mixed with chylous fluid or lymph, which is usually caused by lymphatic obstruction caused by a variety of diseases. A case of recurrent chyluria after retroperitoneal laparoscopic renal pedicle lymphatic disconnection was reported. The patient developed chyluria again 8 months after operation and was cured after sclerotherapy with erythromycin solution.
Application of Clinical Nursing Pathway in Patients Undergoing Endoscopic Submucosal Dissection (ESD)
Authors: He Yazhi , Lin Yan
Published: February 2025

Objective: To explore the role of clinical nursing pathways in preventing complications, promoting recovery, and improving satisfaction in patients undergoing endoscopic submucosal dissection (ESD) during the perioperative period. Method: Forty ESD patients admitted to our hospital from March 2022 to March 2024 were selected as the research subjects. They were randomly divided into a control group and an observation group, with 20 cases in each group. The control group received routine nursing care, while the observation group received clinical nursing pathway. The incidence of complications and recovery time were observed in both groups. Result: ① The total incidence of complications in the observation group was 5.00%, significantly lower than that in the control group (30.00%) (P<0.05); ② The observation group had significantly shorter postoperative first meal time, bed activity time, and hospitalization time compared to the control group (P<0.05). Conclusion: For patients undergoing ESD treatment, implementing clinical nursing pathways during the perioperative period can reduce the incidence of complications and shorten the postoperative recovery time, which is worth promoting.
Research on Ideological and Political Teaching Reform of Basic Nursing Practical Training Course in Higher Vocational Colleges
Authors: Wang Shulin , Gu Luyan , Li Ziling , Wu Haijian
Published: February 2025

With the development of society and the continuous progress of medical industry, the teaching mode of basic nursing practical training course in higher vocational colleges also needs to keep pace with The Times and integrate ideological and political education elements in order to train nursing talents with both moral and technical characteristics. Based on this, this article aims to explore the necessity and implementation strategy of ideological and political teaching reform in the basic nursing practical training course in higher vocational colleges.
Adapting Teaching Methods to Accommodate Diverse Learning Styles in Education
Authors: Yang Can
Published: February 2025

In contemporary higher education, teachers must employ diverse teaching strategies to accommodate different student learning styles. The primary teaching methods include lectures, seminars, demonstrations, and tutorials, each serving specific educational purposes. Learning styles are categorized as visual, auditory, kinesthetic, and various social interaction preferences. Teachers are encouraged to tailor their teaching strategies to meet these differences. This review examines recorded lectures using the FILL+ framework developed by Wood et al., exploring how different teaching activities interact with diverse learning styles. It was found that diverse methods, such as interactive lectures, seminars, and group discussions, better foster student engagement and deep learning, particularly in fields like science, medicine, sociology, and physics education. Additionally, the study discusses strategies for accommodating international students and neurodiverse learners, as well as promoting active learning among students of different proficiency levels. In conclusion, employing multiple teaching strategies can better address diverse student needs and improve educational outcomes. Future research could explore the use of technology in personalized instruction and evaluate the long-term impact of diverse teaching strategies on different disciplines and large-scale classrooms.
Application of Business Law in Educational Management: A Study of Compliance and Legal Risk Management Strategies for Higher Education Institutions
Authors: Zhang Xianliang
Published: February 2025

The paper presents detailed case studies demonstrating the strategic and methodological applications of commercial law in addressing real-world issues. The paper presents detailed case studies demonstrating the strategic and methodological applications of commercial law in addressing real-world issues. These cases encompass contract negotiation, execution, and dispute resolution, underscoring the indispensable role of legal compliance in safeguarding institutional interests and protecting the rights. These cases encompass contract negotiation, execution, and dispute resolution, underscoring the indispensable role of legal compliance in safeguarding institutional interests and protecting the rights of students and faculty. In the section dedicated to legal risk management strategies in educational settings, the paper discusses systematic approaches to risk identification, assessment, response, and monitoring.
Dance Creation Teaching Design with Project Drive as the Core: to Improve Students' Practical Ability
Authors: Su Yafei
Published: February 2025

This study discusses the teaching design of dance creation with project drive as the core, aiming to improve students practical ability and innovative thinking. By constructing a practical project-based teaching framework, this paper emphasizes the importance of project-driven teaching method in dance creation teaching, and analyzes the effectiveness of this method in cultivating students creativity, teamwork spirit and self-reflection ability. The results show that project-oriented teaching can enhance students artistic expression and their ability to solve practical problems, and lay a solid foundation for their future dance learning and career development.
CHALLENGES AND OPPORTUNITIES OF ATTRACTING FINANCING FOR UKRAINIAN ENTERPRISES DURING WARTIME
Authors:   Taras Shevchenko National University of Kyiv, Zozuliuk Ivan
Published: February 2025

The article highlights the current challenges and opportunities for Ukrainian enterprises in
securing financing amid the ongoing military conflict. A detailed analysis is provided of the difficulties businesses face in obtaining financial resources, particularly in the context of economic
instability, increased risks, and limited access to capital during the war. Key factors negatively
impacting the financial capabilities of businesses are highlighted, including heightened political
and military risks, a significant rise in interest rates on loans, and a decline in investment interest
due to the elevated risk levels. The article assesses and compares the cost of raising debt and equity financing before and after the war in Ukraine.
FORECASTING THE EFFICIENCY OF MANAGEMENT OF OPERATIONAL ACTIVITIES OF INNOVATION-ORIENTED ENTERPRISES
Authors:   Kyiv National University of Technology and Design, Rabchuk Serhii
Published: February 2025

The article defines the main aspects and methods of forecasting the effectiveness of management of operational activities of innovatively oriented enterprises. Attention is focused on the fact
that the problem of forecasting the effectiveness of management of operational activities of innovatively oriented enterprises is extremely relevant in modern conditions of rapid technological
changes and global competition. The lack of adequate forecasting methods can lead to low efficiency of operational management, which, in turn, negatively affects the overall competitiveness of
the enterprise. The method of analysis and forecasting of individual effects of the enterprise efficiency management system was proposed and its adaptation was carried out on the example of five
business entities. Forecast values for these enterprises have been calculated for 2025-2027. The
data we received emphasize the importance of a stable and effective management system for maintaining competitive advantages in the market
STATE OF THE BANKING SECTOR AND THE ROLE OF BANKING MANAGEMENT
Authors:   Zaporizhzhia National University, Tkachenko Sergii
Published: February 2025

In modern conditions, banking management is one of the most dynamic areas of the economy. Technological changes, rising inflation, increased competition and stricter regulatory requirements have led to the development of more aggressive management strategies in banks, which
increases the level of risks. As risk management becomes increasingly complex, this can lead to a
deterioration in the asset structure and a decrease in the efficiency of operations, which potentially threatens crisis situations. Therefore, it becomes critically important for bank management to
develop effective approaches to identifying and minimizing risks in order to ensure profitability,
protect depositors' funds and maintain the stability of the bank's operations.
Recently Ukraine’s banking sector has demonstrated extraordinary resilience, remaining a
reliable support for the real economy. There has been no outflow of deposits from the banking system, and access to cash has been ensured even during winter power outages, highlighting the effectiveness of digital technologies and backup mechanisms. The high level of capital adequacy ratio
(CAR) and significant liquidity buffers show that the banking system is ready to cope with current
challenges. This level of stability is comparable to the experience of countries that have rebuilt their
financial systems after crises, such as Finland after the Great Depression.
In addition to important reforms implemented since 2014, comprehensive measures of the
National Bank of Ukraine and a high level of digitalization played a key role in the stability of the banking sector