bluuebunny/crossref_metadata_2025 huggingface dataset:
Pensamiento Económico de Joaquín Balaguer: ideas sobre políticas de desarrollo y manejo del gobierno
Authors: Vásquez Harold
Published: January 2023

Este documento intenta caracterizar el pensamiento económico de Joaquín Balaguer, quien presidió el Gobierno Dominicano durante 23 años, enfocándonos específicamente en la etapa de formación a sus ideas económicas previa a 1966. Iniciamos describiendo algunos eventos políticos y económicos importantes para la República Dominicana de inicios del siglo xx, los cuales entendemos marcaron en Balaguer tanto el interés como algunas de sus posturas económicas. Destacamos el rol que jugó la intervención norteamericana de 1916 en la postura acérrima de Balaguer contra el endeudamiento externo y cómo el Colbertismo, o mercantilismo francés, incidió en una visión de las políticas públicas como impulsora del desarrollo económico dominicano.
Assessment of Jangal Desha in Western Geo-Climatic Region of Rajasthan Based on Ayurvedic Parameters
Authors: Shukla Dr. Shubham , Sharma Dr. Rajesh Kumar , Sharma Dr. Dinesh Chandra
Published: January 2023

Abstract: Desha and Disha are concepts used in Ayurveda to describe both health and sickness. Desha has been used in two ways. The first is for land/any geographical place, and the second is for body and mind. Atura Desha is the name given to humans. Both forms of Desha are discussed in Ayurvedic texts, and their interrelationship is also acknowledged. Desha is the name for a geographical area's topography-climate-vegetation profile in both thoughts (Ayurveda & modern). So, there was a need to explore this gap by a study that what part will be consider as a Jangal Desha. The paper intends to explain the clinical perspective & application of concept of Jangal desha with both thoughts.
A study to assess the Effectiveness of Structured Teaching Program on knowledge regarding Iron Deficiency Anemia among Adolescent girls of Swami Dayananda Saraswati Inter College at Ayodhya, Uttar Pradesh
Authors: Pandey Suman
Published: January 2023

Abstract: Introduction-Iron is an important micronutrient which is Very Important for various functions in human body. It is essential for cellular growth and differentiation, oxygen binding, transport and storage, enzymatic reactions, immune function, cognitive function, mental and physical growth etc. So, deficiency of iron due to either physiological or pathological reason can affect mental and physical growth resulting in decreased learning capacity and work productivity. Iron Deficiency Anemia is characterized by a defect in haemoglobin synthesis, resulting in hypochromic and microcytic red blood cells. Iron deficiency can result either due to less nutritional supply, increased demand or blood loss due to any reason. Anemia is a serious global public health problem that particularly affects young children, Adolescent and pregnant women. Although IDA occurs at all ages and involves both sexes, adolescent girls are more prone to it. The World Health Organization (WHO) defined adolescents as the population of 10-19 years of age.
Distribución de las comunidades epibentónicas y caracterización de hábitats en el fiordo Puyuhuapi (45°S)
Authors: Ortiz Saini Paula , Hamamé Villablanca Madeleine
Published: January 2023

Las comunidades bentónicas de la Patagonia chilena presentan una alta biodiversidad en respuesta a la variabilidad de las condiciones ambientales, fuentes de alimentos y hábitats. Este estudio caracterizó una comunidad epibentónica con altos valores de riqueza de especies, dominada por suspensívoros distribuidos en diferentes tipos de hábitats a lo largo del fiordo Puyuhuapi. Múltiples variables ambientales definieron la composición y distribución de estas comunidades; siendo la profundidad y la inclinación y tipo de sustrato determinantes para la epifauna. En este fiordo, el grupo trófico asociado a los alimentadores en suspensión, representan un rasgo funcional que puede tener funciones ecosistémicas importantes asociadas a los ciclos del carbono y de los nutrientes. Razón por la cual, la información espacio-temporal y funcional de estas comunidades son un insumo fundamental para el monitoreo de estos ecosistemas, especialmente en fiordos con alto impacto de actividades antrópicas como la salmonicultura.
Analytical surfaces for architecture and engineering
Authors: Gil-Oulbé Mathieu , Daou Tiékolo , Mariko Ousmane
Published: January 2023

Geometers have proposed more than 600 analytical surfaces for implementation. The largest number of these surfaces is used in architecture and mechanical engineering. Although digital architecture and free form architecture are now increasingly influencing the design of long-span shell structures and curved buildings, the research and application of analytical surfaces continues on an increasing scale. The purpose of the research is to study the state of affairs in the application of analytical surfaces in the construction and engineering industries and to clarify the classes of surfaces that have found application in the study of physical phenomena or in solving purely mathematical problems, but not used in other areas of human activity. Another goal is to find analytical surfaces promising for application in architecture and mechanical engineering, which are still little known to architects and engineers. It has been established that, as before, designers take new analytical surfaces to implement their creative ideas from well-studied classes of surfaces of revolution, transfer and umbrella, minimal, ruled, wavy surfaces.
Different Clinicopathological Characteristics in Indonesian Colorectal Patients with NRAS Mutations and HER2 Expression
Authors: Lukman Kiki , Reza Ade Tan , Diposarosa Rizki , Rudiman Reno , Sribudiani Yunia , Bashari Muhammad Hasan , Primastari Etis , Nugraha Prapanca
Published: January 2023

Abstract Objective: Colorectal cancer (CRC) is the world’s third most
common type of cancer. Data in Indonesia based on GLOBOCAN in 2020 shows
CRC in the fourth position with around 35,000 new cases each year. The
pathogenesis mechanisms of CRC are complex and heterogeneous, one of
which is the involvement of NRAS (Neuroblastoma Rat Sarcoma viral
oncogene homolog) mutations which play a role in cell growth regulation,
as well as the expression of Human epidermal growth factor receptor 2
(HER2). This study aims to assess the association of subject
characteristics and NRAS mutations with HER2 expression in CRC. Methods:
This research is a cross-sectional study. There were 58 patients
included in this study, they were colorectal cancer patients in the
Digestive Surgery division at Dr. Hassan Sadikin Hospital. Examination
of NRAS mutations was carried out by Polymerase Chain Reaction (PCR)
from fresh tumour tissue obtained from surgery or colonoscopy.
Meanwhile, HER2 examination used the Immunohistochemistry (IHC) method
of paraffin blocks for anatomical pathology examination. Result: HER2
overexpression was found in 6/58 (10.3%) patients with CRC, and from 8
subjects with NRAS mutations, only 1 subject (1.7%) showed
overexpression of HER2. Univariate analysis of HER2 expression showed no
significant associations to age, sex, histologic feature, tumor
location, and NRAS mutations. A significant association was found
between HER2 expression and stadium of the CRC with p=0.001. Conclusion:
There is no association between NRAS mutations and HER2 overexpression
in colorectal cancer patients.
Impact of postpartum anemia treatment with intravenous ferric carboxymaltose, intravenous ferric derisomaltose or oral ferrous sulphate on maternal fatigue: a randomized clinical trial
Authors: TAVČAR Lea BOMBAČ , HROBAT Hana , GORNIK Lea , Simic Marijana Vidmar , PEČLIN Polona , ZUPAN Irena PRELOŽNIK , KAVŠEK Gorazd , Lucovnik Miha
Published: January 2023

Objective: To compare intravenous ferric carboxymaltose,
intravenous ferric derisomaltose and oral ferrous sulphate for treatment
of postpartum anemia. Design: Single-center, open-label,
randomized trial. Setting: Tertiary perinatal center.
Population: Three-hundred women with postpartum anemia
(hemoglobin < 100 g/L within 48-hours postpartum) were
included between September 2020 and March 2022. Methods: Women
were randomly allocated to receive intravenous ferric carboxymaltose,
intravenous ferric derisomaltose or oral ferrous sulphate. Intravenous
iron was given in one or two doses, while ferrous sulphate as two 80 mg
tablets once daily. Main outcome measures: Primary outcome was
maternal fatigue measured by Multidimensional Fatigue Inventory (MFI)
six weeks postpartum. Hemoglobin, ferritin and transferrin saturation
levels were analyzed as secondary outcomes. Kruskal-Wallis test was used
for group comparison (p<0.05 significant). Results:
MFI score at six weeks postpartum did not differ between groups (median
38 (inter-quartile range (IQR) 20-74) in the ferric carboxymaltose,
median 34 (IQR 20-70) in the ferric derisomaltose, and median 36 (IQR
20-72) in the ferrous sulphate group; p=0.26). Participants receiving
oral iron had lower levels of hemoglobin (135 (119-150) vs 134 (113-157)
vs 131 (125-137) g/L; p=0.008), ferritin (273 (198-377) vs 187 (155-246)
vs 24 (17-37) µg/L; p<0.001) and transferrin saturation (34
(28–38) vs 30 (23–37) vs 24 (17-37) %; p<0.001) than those
receiving ferric carboxymaltose or ferric derisomaltose.
Conclusions: Intravenous ferric carboxymaltose, intravenous
ferric derisomaltose and oral ferrous sulphate had similar impact on
maternal fatigue at six weeks postpartum despite improved hematological
laboratory parameters in the intravenous iron groups.
Calcium oxalate crystal macropattern and its usefulness in the taxonomy of Baccharis (Asteraceae)
Authors: Raeski Paola , Heiden Gustavo , Novatski Andressa , Raman Vijayasankar , Khan Ikhlas Ahmed , Manfron Jane
Published: January 2023

This study provides a comprehensive account of the various types of
calcium oxalate crystals found in the genus Baccharis and
assesses the exceptional value of crystal macropatterns for the taxonomy
of the genus. The morphotype, occurrence and chemical composition of the
crystals found in the stems and leaves are studied. The 44 species
included in this study were selected based on a broad phylogeny-based
sampling covering seven subgenera and 31 sections. These species were
chosen to represent all the main phylogenetic lineages of
Baccharis; thus, the sampling also represents a comprehensive
coverage concerning evolutionary significance for such a large and
environmentally and economically important plant group. The samples were
analyzed by light microscopy, scanning electron microscopy (SEM), and
energy-dispersive X-ray spectroscopy (EDS). Several morphotypes of
crystals, including druses, crystal sand, styloids and prisms, were
present. Based on their chemical composition, the crystals were
classified as pure calcium oxalate, mixtures of oxalates and sulfates,
and mixtures of oxalates, sulfates and silica. The crystal macropatterns
observed in this study aid in the species identification and provide
novel data for the taxonomy of Baccharis.
Government intervention and M&A performance: From the perspective of target corporate social responsibility overinvestment
Authors: guo jianquan , Wang Hongdi
Published: January 2023

Based on a sample of cross-border mergers and acquisitions (M&As) of
Chinese enterprises in different target countries between 2000 and 2021,
this paper explores the impact of target corporate social responsibility
overinvestment on M&A performance and the moderating effect on the
above impact of Chinese government’s two forms of interventions in the
process of corporates financing and operating. The results show that
target corporate social responsibility overinvestment has a negative
effect on M&A performance. Moreover, government interventions in
corporates’ financing and operating process negatively moderate the
relationship between target corporate social responsibility
overinvestment and M&A performance. This research helps government to
take different forms of interventions to motivate enterprises to
participate in social responsibility and improve performance.
Architecture of contemporary spa hospitality - current tendencies in designing spa hotels
Authors: Brzakovic Milan , Nikolic Marko , Milojkovic Aleksandar
Published: January 2023

The emergence of spa tourism as a sector of the wellness tourism marketplace
is reflected in contemporary architecture of spa hotels. These facilities
are essentially accommodation facilities that offer a variety of individual
treatments and services for spaseeking tourists focused on their health and
wellness. The primary objective of the research is to investigate current
tendencies and strategies in the field of architectural design of spa
hotels, as well as to explore successful design approaches. The research
begins with elaboration of basic characteristics of modern wellness tourism,
followed by the definition of spa hotel as a special type of hospitality
facility. Later, classification of modern spa hotel modalities is elaborated
and further clarified using relevant case studies. The second part of the
research is the analysis of recognized design tendencies in terms of spatial
organization of spa hotels. In the conclusion, their further applicability
in wider practice is discussed, and certain disadvantages and limitations
are listed.
The concept of “surface depth” in architecture
Authors: Alfirevic Djordje , Simonovic-Alfirevic Sanja
Published: January 2023

In history of art and architecture, surface has always been the bearer of
symbolic and aesthetic values, the subject of theoretical and critical
analysis, with various ideological, discursive and philosophical
interpretations. The subject of this research paper are different concepts
of composition, artistic elements and materialisation of fa?ade surfaces,
which have the effect of ?surface depth? as their primary characteristic. By
analysing the potential of this concept in articulation of the structure of
fa?ade and other surfaces, three main emergent forms were noted: plasticity
of surfaces (the use of small fa?ade plastics), double skin fa?ade with
unused in-between space and double skin fa?ade with used in-between space.
By conducting scientific analyses of theoretical reference sources and
characteristic examples, along with the application of the deductive
methods, the characteristics of the ?surface depth? concept in architecture
were explored, with the aim of systematizing the principles used to achieve
it, the possibilities of its application, as well as ways to establish the
dual character of spatial planes - surface and volume. This research has
contributed to the clarification of this concept and laid the foundation for
further research in the direction of finding, chronologically ordering and
analysing other examples, in order to enable their more extensive typology
and systematization.
Space Syntax Analysis on Edu-Tourism Accessibility (Case Study: Planetarium UIN Walisongo Area)
Authors: Adi Alifiano Rezka , Riyadi Selamet
Published: January 2023

Planetarium UIN Walisongo is an educational facility that not only accommodates academic needs but is also projected to become a tourism destination in Semarang. The density of activity is the main focus that must be considered. The building's existence in the middle of the campus also demands that it has good visual access. The study focused on configuration and visibility analysis by looking at their effect on accessibility around the building. The research was conducted using quantitative methods with a descriptive and simulation framework. The simulation process is carried out using a space syntax approach with Depthmap software. Macroanalysis shows that the building is located in the central area with a relatively high integration value. The high intelligence value shows that the spatial configuration is relatively easy to recognize. The wide and integrated road makes this area have relatively high visibility. Microanalysis shows that the pedestrian around the Planetarium is not well connected. Space engineering by connecting pedestrians is carried out to provide better accessibility. Achievement efficiency is the main consideration to produce a high value of integration and visibility around the building. Therefore, the area quality will be better with an accessible space on macro and micro scales
Fungsi dan Tata Letak Ruang dalam Bangunan Etnik pada Kawasan Permukiman Kampung Melayu Semarang
Authors: Agustina Monaliza , Agustian Endy
Published: January 2023

Kampung Melayu Semarang merupakan kawasan budaya multietnik antara etnik Arab, Tionghoa, Bugis Banjar dan etnik lainnya dari luar Semarang. Bangunan rumah-rumah yang ada pada kawasan Kampung Melayu Semarang memiliki karakteristik ruang sesuai dengan masing-masing etnik. Penelitian ini bertujuan untuk mengidentifikasi dan mengkomparasi masing-masing fungsi dan tata letak ruang dalam bangunan rumah-rumah berbagai etnik di kawasan Kampung Melayu Semarang. Metode penelitian yang digunakan untuk mencapai tujuan tersebut menggunakan metode deskriptif kualitatif, serta teknik pengumpulan data melalui observasi dan wawancara. Hasil penelitian menunjukkan bahwa fungsi rumah dari masing-masing etnik memiliki kesamaan sebagai rumah tinggal atau tempat berlindung bagi masyarakat, namun pada etnik Tionghoa rumah tinggal juga berfungsi sebagai tempat berdagang. serta penataan ruang dalam bangunan rumah tinggal setiap etnik juga berdasarkan pada kebutuhan, aktivitas dan kegiatan masing-masing penghuninya.
The Contribution of Authoritarian Parenting Perceptions on High School Students' Confidence
Authors: Wati Tita Setiya , Komarudin Komarudin
Published: January 2023

Having self-confidence is very necessary in living life in order to be able to pass the stages of development well. Appearing with confidence is one of the keys to success in living life with a social environment such as friends and society. Without self-confidence, individuals will experience many problems within themselves. One of the factors that influence self-confidence is interaction and parenting applied by parents. The purpose of this study was to determine the relationship between perceptions of authoritarian parenting and self-confidence in high school students in Yogyakarta. This study uses a quantitative method with a correlation approach. Respondents in this study were high school students in Yogyakarta. The number of respondents as many as 80 students. The sampling technique used was purposive sampling. Data retrieval using scale filling. Data analysis using Pearson Product Moment correlation. The results showed that respondents had a perception of authoritarian parenting in the medium category with a percentage of 86.3% (69 people), while the respondents' self-confidence was at a moderate level with a percentage of 85% (68 people). Based on the data on the results of the determination test (R Square) which shows that the test results (R²) are worth 0.115 or 11.5%. Perceptions of authoritarian parenting contributed 11.5% to self-confidence. There is a significant negative relationship between the perception of authoritarian parenting and self-confidence in high school students in Yogyakarta. So that the higher students' perceptions of authoritarian parenting, the lower their self-confidence, and vice versa, the lower students' perceptions of authoritarian parenting, the higher their self-confidence.
Literatura e hospitalidade: uma leitura do poema “A pantufa”, de Patrícia Lino
Authors: De Moraes Paulo Eduardo Benites , Maciel Josemar De Campos
Published: January 2023

Nosso objetivo com este texto é realizar uma análise do poema “A pantufa”, da poeta Patrícia Lino. O poema em questão fora publicado em 2019 no blog e revista Études Lusophones e já foi apresentado na Espanha, Portugal e Estados Unidos. Para realizar a análise tomamos como ponto de partida a relação entre literatura e filosofia, mais especificamente as discussões em torno do conceito de hospitalidade, pensado por Jacques Derrida. O problema central da discussão está centrado na categoria de hospitalidade tomando-a como hipótese de trabalho, entendendo que ela se constrói como um dispositivo ético, estético e político capaz de sustentar a porosidade entre os estudos literários e a filosofia. Para tanto, em um primeiro momento passamos pelo conceito de hospitalidade, sua expansão para o diálogo com a literatura naquilo que vem sendo chamado de poética da hospitalidade para, ao final, propor a leitura e análise do poema em questão.
“Life sucks, coffee helps”: Articulating the authentic entrepreneur on YouTube's girlboss channels
Authors: Roivainen Ida
Published: January 2023

Common depictions of authentic self-presentation on social media are often interpreted through the lens of ambivalence, performance, or some kind of bind. Through the example of millennial women who call themselves girlbosses, this article explores how authenticity is articulated through three levels: productivity, ordinariness, and belonging. The study is part of a larger netnographic project in which 23 YouTube channels and related social media platforms have been observed for two years. Content analyses of observational and interview data suggest the authentic self is often represented and expressed through specific cultural repertoires (e.g., coffee) that articulate girlbosses as productive and ordinary entrepreneurs seeking belonging and meaning. Further, while digital media allows new kinds of entrepreneurship, at the same time, self-employed digital workers, influencers, and entrepreneurs are left alone to advance their careers in the midst of rising popular misogyny and lacking job security. I argue that participating in communicative practices of entrepreneurial femininity offers girlbosses a promise of happiness if they stay “authentic”; and yet, in a cruel way, this promise also prevents itself from actualising.
Adolescents, new social relations and media practices: a research in the Metropolitan City of Bologna (Italy)
Authors: Pacetti Elena , Soriani Alessandro , Bonafede Paolo
Published: January 2023

Currently almost 99% of Italian teenagers own a smartphone and with it they can enter the world of the infosphere: this fact has profoundly changed the online habits of teenagers. The pedagogical literature grafted onto Media Education has highlighted the cognitive and relational opportunities favoured by smartphones and their use by adolescents. Which are today’s adolescent’s online media-practices? In which terms these practices have an impact on adolescents’ socialisation? This contribution intends to explore these questions and focus attention on the ways in which these devices are managed by teenagers on a personal level, offering a descriptive picture of the media practices activated in the context of the reticular society for the school and family context and consequent reflections on identity and on the sociability of adolescents.

The research involved nine upper secondary schools with different curricula in the Metropolitan City of Bologna (1657 students, age 14–19) in school year 2020/2021. The data collected through questionnaires and focus groups highlight how technologies and social media play a role of fundamental importance not only as daily mediators in the relationships of young adolescents but also as a space for negotiation of their identity. And this role was crucial for their well-being during periods of lockdown due to Covid-19.
The processes of remediation between digital and analog artefacts to enhance student learning
Authors: Marzano Antonio
Published: January 2023

In recent years, numerous researches have been carried out to investigate and verify how concept maps could be effective in learning management systems. This paper discusses the use of dynamic concept maps (DCMs) as a tool to encourage remediation processes among digital artefacts and analog resources and, consequently, to enhance learning processes and improve their effectiveness. The DynaMap remediation approach (DMRA) intends to propose a possible interpretation of this process by using Vygotsky’s historical-cultural approach, enriched and contaminated by the perspective of mutual remediation of Bolter and Grusin inspired to McLuhan’s theories. The research carried out in the last five years shows how this methodology (DMRA) has positively influenced study times and learning outcomes of the engaged students.
Participatory Communication and Shared Leadership: The European Project Learning Leadership for Change (L2C)
Authors: Turchi Antonella , Greco Serena , Morini Elettra , Nencioni Paola
Published: January 2023

Schools are a complex system made up of not only relationships, infrastructures, and challenges, but also constraints. It seems essential that schools, as complex organizations, work in synergy, according to a shared vision with all the actors involved in the educational process. School management is now part of a process that is increasingly implemented in a shared way; a single person in charge cannot manage the complexity that the school requires.  

In order to observe and narrate this complexity, the National Institute of Documentation, Innovation, and Educational Research (INDIRE) has carried out several research projects in recent years that focus on the analysis of school leadership. In particular, the European project Learning Leadership for Change (L2C) aimed to promote and support the experimentation of a shared leadership approach in some strategic areas for schools. 

The results of this project highlighted the importance of the lighthouse leaders in implementing shared leadership, whose main function is to involve all school actors keeping the community active and growing. These more informal teams do not remove the need for the so-called formal intermediate management structures. It is also essential for the shared leadership approach to create sharing networks that include local and regional strategic partners to reinforce the sustainability of these innovative practices.
An application of a multiindex, time-fractional differential equation to evaluate heterogeneous, fractured rocks
Authors: Raghavan Rajagopal , Chen Chih
Published: January 2023

A multiindex, distributed fractional differential equation is derived and solved in terms of the Laplace transformation. Potential applications of the proposed model include the study of fluid flow in heterogeneous rocks, the examination of bimodal fluid exchange between mobile-immobile regions in groundwater systems, the incorporation of the existence of liesegang bands in fractured rocks, and addressing the influences of faulted and other skin regions at interfaces, among others. Asymptotic solutions that reveal the structure of the resulting solutions are presented; in addition, they provide for ensuring the accuracy of the numerical computations. Fractional flux laws based on Continuous Time Random Walks (CTRW) serve as a linchpin to account for complex geological considerations that arise in the flow of fluids in heterogeneous rocks. Results are intended to be applied at the Theis scale when combined with geological/geophysical models and production statistics to all aspects of subsurface flow: production of geothermal and hydrocarbon fluids, injection of fluids into aquifers, geologic sequestration and hazardous waste disposal. Results may be extended to study the role of complex wellbores such as horizontal and fractured wells and more complex geological considerations such as faulted systems.
Secularization of Interest in Early Christianity: A Sociological Analysis of Economic Institutions
Authors: DÜNDAR Onur
Published: January 2023

In this paper investigates the traces of financial institutionalization in early Christianity with a focus on halalization (secularization) of the concept of interest. Secularization is being discussed in the context of monasticism since the period in focus is early Christianity. In the study, monasticism is classified into three types: Classical, Cenobitic, and Benedictine. For its research purposes, the study employs qualitative methods like using a case study design. In addition, primary and secondary sources are reviewed to obtain data. Later, this obtained data is analysed through descriptive and process analyses. The role of interest in Classical Monasticism is analysed through descriptive analysis, which ascertains that there was a parallelism between the increase in organising based on an economic mentality and the secularization of interest. Moreover, it is discovered that there were organizational forms with a tendency towards institutionalization. These were mainly: (1) organizational forms regarding the division of labour and specialization that were surrounded by some regulations and (2) organizational forms that laid the foundation for the modern (secularized) concept of interest which became the time value of money when a socio-temporal order was established.
FAKE NEWS, LETRAMENTO INFORMACIONAL E SAÚDE
Authors: Divino Sthéfano Bruno Santos , Oliveira Júlia Cavalcanti de , Alves Ingrid Drumond Correia
Published: January 2023

O presente artigo tem como problema de pesquisa o seguinte questionamento: pode autoridades políticas (enquanto agentes políticos) serem responsabilizadas pelo discurso caracterizado como Fake News? Objetiva-se demonstrar os limites da liberdade de expressão com fundamento no direito brasileiro, direito estadunidense e no direito italiano. A hipótese proposta é que a liberdade de expressão pode ser exercida em dois níveis: o nível da pessoa física e o nível da pessoa jurídica de direito privado. Com essa constatação, verifica-se que a liberdade de expressão é incompatível com a pessoa jurídica de direito público em razão de sua constituição ontológica, cujo exercício é destinado contra o próprio Estado. Portanto, como resultado, verifica-se que o discurso proferido por autoridades políticas se restringe unicamente à sua esfera subjetiva e pessoal, desvinculando-se da instituição estatal. Caso esse discurso seja pautado em Fake News ou inverdades e possa causar dano à sociedade em razão da influência exercida por essa autoridade política, verifica-se a possibilidade de responsabilização pelos danos acometidos. O fundamento jurídico pauta-se nos riscos administrativos advindos da gestão pública. Dessa forma, conclui-se que a liberdade de expressão, no sistema jurídico brasileiro, possui uma limitação quanto ao interesse social e não pode ser exercida de forma arbitrária ou ilimitada. Para tanto, utiliza-se o método de pesquisa monográfica, o método dedutivo e a técnica de pesquisa bibliográfica.
O impacto da Covid-19 na saúde mental das crianças, jovens e adolescentes
Authors: Vieira Gabriella de Almeida , Vieira Rafaella de Almeida , Almeida Leandra de Almeida Werneck , Zamboni Giullia de Araújo , Pimentel Juliana Peres , Torres Larissa Lima , Oliveira Carla Rezende Vaz , Reis Bruno Cezario Costa
Published: January 2023

Objetivo: Analisar os impactos dos bloqueios governamentais na saúde mental da população infanto-juvenil e assim prevenir ou diminuir as consequências na vida adulta visto que são negligenciados e mal compreendidos pelos profissionais de saúde e pela população em geral. Métodos: A abordagem metodológica se propõe a um compilado de pesquisa bibliográfica por meio de uma revisão integrativa da literatura nas bases de dados National Library of Medicine, Biblioteca Virtual em Saúde e Directoryof Open AccessJournals. Os descritores utilizados foram “depression”, ‘’anxiety”, ‘’Covid-19’’ e “child”. Os critérios de inclusão foram artigos de journal article, clinicaltrial, ensaios clínicos, randomizados ou não randomizados, estudos de caso-controle, estudo de coorte, livre acesso, publicados em inglês, português, espanhol, no intervalo de 2020 a 2022 e faixa etária de 0 a 21 anos. Resultados: O sexo feminino é mais suscetível as doenças psíquicas quando comparados com o sexo masculino e foram avaliadas que entre as principais enfermidades como ansiedade, depressão, insônia, estresse pós-traumático e insônia, a ansiedade e depressão são as mais comuns. Considerações Finais: Dessa forma, negligenciar o aumento dos casos de depressão e ansiedade entre essa faixa etária da população favorece complicações na vida adulta e prejuízos na saúde mental dessas pessoas dificultando, assim, seu desenvolvimento em diversos segmentos da vida.
O risco do tabagismo passivo no desenvolvimento de pneumopatias
Authors: Egger Pedro Acácio Lemos , Pereira Ana Clara Fiuza , Barenco Bárbara Pires de Mello , Pereira Carlla Alessandra Silva , Lussari Laila Maria Corrêlo , Moreira Luísa Leite , Brito Lara Pereira de , Capute Victória Emmanuela Thomé Bragança , Conceição Willian Faustino da , Rabello Eucir
Published: January 2023

Objetivo: Analisar o desenvolvimento de síndromes respiratórias correlacionadas com o tabagismo passivo. Métodos: Trata-se de uma revisão integrativa. Foram utilizadas as bases de dados do portal regional da Biblioteca Regional em Saúde. A busca dos artigos foi feita por meio de descritores, sendo eles “passive smoking”, “risk” e “lung disease”. A revisão foi realizada seguindo as seguintes etapas: estabelecimento do tema, definição dos parâmetros de elegibilidade, definição dos critérios de inclusão e exclusão, verificação das publicações nas bases de dados, análise das informações encontradas, avaliação dos estudos encontrados e exposição dos resultados. Resultados: Foi observado que os danos causados pelo tabagismo passivo podem gerar uma série de consequências negativas para a saúde em geral, como risco para o desenvolvimento de doenças cardíacas e doenças respiratórias e, principalmente, as neoplasias malignas. Esse compilado de fatores, demostra a necessidade do combate ao tabagismo e consequentemente ao tabagismo passivo. Considerações finais: Diante dos fatos mencionados, foi possível inferir que a inalação passiva da fumaça do cigarro aponta para maior risco de agravar ou desenvolver doenças respiratórias, tais como asma, DPOC e câncer de pulmão.
Influência da gestação no desenvolvimento da tireoidite pós-parto: principais fatores desencadeadores
Authors: Medeiros Danielle Tiburcio de , Nogueira Raquel Bezerra de Sá de Sousa , Sousa Milena Nunes Alves de , Nogueira Tiago Bezerra de Sá de Sousa
Published: January 2023

Objetivo: Conhecer quais os principais fatores desencadeadores da tireoidite pós-parto durante a gestação. Métodos: Consiste em um estudo secundário, com uma abordagem quantitativa, do tipo revisão bibliográfica integrativa, em que foram utilizados Descritores em Ciências da Saúde (DeCs) em inglês “Postpartum Thyroiditis" e "Pregnancy" para a busca de trabalhos nas bases de dados Biblioteca Virtual em Saúde (BVS) e Medical Publisher (PUBMED). Dos 138 artigos encontrados que passaram pelo crivo dos critérios de inclusão e exclusão 12 estudos foram utilizados nesta pesquisa. Resultados: Observou-se que a maioria dos estudos indicam a positividade do anticorpo TPOAb como uma das principais causas para desencadear a tireoidite pós-parto, seguido da disfunção da tireoide, doenças autoimunes, deficiência nutricional do selênio e níveis altos de anti C1q durante a gestação. Considerações finais: A positividade do anticorpo TPOAb durante a gestação é o principal fator desencadeador da tireoidite pós-parto, contudo, são necessários mais estudos clínicos sobre a tireoidite pós-parto para auxiliar no diagnóstico precoce através da triagem no pré-natal, favorecendo o tratamento adequado e qualidade de vida da mulher.
Physiological Indices and Yield Traits of Wheat Genotypes under Drought Stress Condition
Authors: Jannat Sedratul , Hasan Md. Abu , Bari Chowdhury A. K. M. M. , Hafiz M. Hafizur Rahman , Sinthy Tanjum Ara , Pramanik Subrota Kumer , Islam Md. Rabiul
Published: January 2023

We assessed the physiological parameters and yield traits of wheat genotypes under water limiting drought condition following split plot design with three biological replications at Department of Crop Physiology and Ecology, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh. The main plot treatment consisted of two water regimes (adequate water and drought condition) while four wheat genotypes (E 38, BAW 1118, BARI Gom 26 and BAW 1130) were assigned as sub-plot treatments. We observed that physiological traits of wheat were adversely affected due to drought environment than normal condition. Even yield of genotypes greatly reduced (37.03-54.44%) because of water scarcity in drought plots. However, wheat genotypes BAW 1118 and E 38 revealed more chlorophyll steadiness, more capability to conserve sufficient water and content of higher proline, soluble sugar and cell membrane stability as compared to BARI Gom 26 and BAW 1130 under water deficit condition. The order BAW 1118 > E 38 > BARI Gom 26 > BAW 1130 was exposed as the imperious level of tolerance centered on their yield. Yield contributing factors, for instance, different spikes characteristics and thousand grain weights at water deficiency situation assisted to enhance greater tolerance of BAW 1118 and E 38 genotypes.
Analisis Pengaruh Pengetahuan Dan Keterampilan Terhadap Komitmen Organisasional Dan Kinerja Pegawai Dinas Perhubungan Kabupaten Kubu Raya
Authors: Marlinda Nanda , Daud Ilzar , Christiana Maria
Published: January 2023

Dinas Perhubungan memiliki visi terwujudnya penyelenggaraan pelayanan perhubungan yang handal, berdaya saing dan memberikan nilai tambah dan misi yang meliputi mempertahankan tingkat jasa pelayanan sarana dan prasarana perhubungan. Dinas perhubungan Kabupaten Kubu Raya langsung berhubungan teknis dengan pelayanan kepada masyarakat yaitu pada Unit Pelaksana Teknis. Tujuan Penelitian ini adalah untuk mengetahui pengaruh pengetahuan dan keterampilan terhadap komitmen organisasional dan kinerja pegawai Dinas Perhubungan Kabupaten Kubu Raya. Bentuk penelitian ini adalah menggunakan deskriptif dengan pendekatan kuantitatif. Pengumpulan data menggunakan data sekunder berupa data yang bersumber dari Dinas perhubungan Kabupaten Kubu Raya. Teknik analisis menggunakan analisis path. Hasil penelitian ini menunjukkan bahwa variabel pengetahuan dan keterampilan berpengaruh terhadap Komitmen Organisasional, variabel pengetahuan dan keterampilan berpengaruh terhadap kinerja dan komitmen organisasional berpengaruh terhadap kinerja.
A cluster of broadly neutralizing IgG against BK polyomavirus in a repertoire dominated by IgM
Authors: Nguyen Ngoc-Khanh , Devilder Marie-Claire , Gautreau-Rolland Laetitia , Fourgeux Cynthia , Sinha Debajyoti , Poschmann Jeremie , Hourmant Maryvonne , Bressollette-Bodin Céline , Saulquin Xavier , McIlroy Dorian
Published: January 2023

The BK polyomavirus (BKPyV) is an opportunistic pathogen, which is only pathogenic in immunosuppressed individuals, such as kidney transplant recipients, in whom BKPyV can cause significant morbidity. To identify broadly neutralizing antibodies against this virus, we used fluorescence-labeled BKPyV virus-like particles to sort BKPyV-specific B cells from the PBMC of KTx recipients, then single-cell RNAseq to obtain paired heavy- and light-chain antibody sequences from 2,106 sorted B cells. The BKPyV-specific repertoire was highly diverse in terms of both V-gene usage and clonotype diversity and included most of the IgM B cells, including many with extensive somatic hypermutation. In two patients where sufficient data were available, IgM B cells in the BKPyV-specific dataset had significant differences in V-gene usage compared with IgG B cells from the same patient. CDR3 sequence–based clustering allowed us to identify and characterize three broadly neutralizing “41F17-like” clonotypes that were predominantly IgG, suggesting that some specific BKPyV capsid epitopes are preferentially targeted by IgG.
PKCβII activation requires nuclear trafficking for phosphorylation and Mdm2-mediated ubiquitination
Authors: Min Xiao , Wang Shujie , Zhang Xiaohan , Sun Ningning , Kim Kyeong-Man
Published: January 2023

PKCβII, a conventional PKC family member, plays critical roles in the regulation of a variety of cellular functions. Here, we employed loss-of-function approaches and mutants of PKCβII with altered phosphorylation and protein interaction behaviors to identify the cellular mechanisms underlying the activation of PKCβII. Our results show that 3-phosphoinositide–dependent protein kinase-1 (PDK1)–mediated constitutive phosphorylation of PKCβII at the activation loop (T500) is required for phorbol ester–induced nuclear entry and subsequent Mdm2-mediated ubiquitination of PKCβII, whereas ubiquitination of PKCβII is required for the PDK1-mediated inducible phosphorylation of PKCβII at T500 in the nucleus. After moving out of the nucleus, PKCβII interacts with actin, undergoes inducible mTORC2-mediated phosphorylation at the turn motif (T641), interacts with clathrin, and then translocates to the plasma membrane. This overall cascade of cellular events intertwined with the phosphorylation at critical residues and Mdm2-mediated ubiquitination in the nucleus and along with interactions with actin and clathrin plays roles that encompass the core processes of PKC activation.
A STUDY OF EXPERT SYSTEM FOR DETECTION OF VARIOUS DISEASES
Authors:   CFY King Saud University, Saudi Arabia, Taqui Ahmed Siddiqui Anjum
Published: January 2023

In the field of medical regularly handles enormous amounts of data. Handling huge data by conventional methods can affect the results. Algorithms for machine learning can be used to find out facts in medical research, in particular for disease prediction. Expert System with artificial intelligence technology, Data mining technology has also been extensively developed, which has promoted the development of for detection and diagnosis of different diseases. The purpose this study aims to know the detection of brain, heart, kidney etc with the help of different algorithms such as Feedforward Backpropagation, Support Vector Machine, Generalized Regression Neural Network, Radial Basis Function and association rules in data mining. This study introduces the above neural network techniques in detail and experiments on medical data collected from hospital. The experimental results show that the some neural network techniques will detect the disease based on medical data collected from hospital and recommend medicine. Applying neural network techniques and data mining techniques based medical data disease detection has greatly improved the level of medical detections and understandings.
DIREÇÕES ATUAIS DA AUTONOMIA, ADMINISTRAÇÃO E GESTÃO DAS ESCOLAS EM PORTUGAL: APONTAMENTOS FREIREANOS
Authors: Pereira Ramalho Henrique Manoel
Published: January 2023

Este ensaio tece considerações e relações, mais ou menos dissonantes, estabelecidas entre o pensamento fundamental freireano e o atual regime de autonomia, administração e gestão das escolas públicas portuguesas. O objetivo central é contribuir para ressituar as transformações ocorridas na gestão escolar em Portugal, procurando (re)interpretá-las com recurso à teoria educacional de Paulo Freire. Temos em confrontação um texto e respetivas narrativa e racionalidade de pendor oficial, com efeitos prescritivos de um modelo de organização e gestão escolar, e as propostas freireanas sobre a administração da educação. Porquanto, desenvolvemos o nosso ensaio em torno da metodologia do círculo hermenêutico aplicada ao estudo da administração e gestão escolares. Em termos conclusivos asseveramos a tendência para o regime de autonomia e administração das escolas se mostrar refém da ideologia da despolitização da administração pública, subjugando os processos de participação escolar à política de resultados.
O PODCAST NO ENSINO E APRENDIZAGEM DE LITERATURA NA EDUCAÇÃO BÁSICA: UM ESTUDO EM UMA ESCOLA PÚBLICA MUNICIPAL EM UBERLÂNDIA, MG, COM ÊNFASE NOS ALUNOS PROTAGONISTAS.
Authors: Teixeira Rodrigues Sara Fernandes , Ferreira Brettas Anderson Claytom , Pereira Otaviano José
Published: January 2023

O trabalho aqui apresentado demonstra os resultados do estudo realizado sobre como o podcast pode contribuir para o ensino e aprendizagem de Literatura na educação Básica, sob os conceitos da Educação Tecnológica. Assim, neste recorte, objetivou-se demonstrar as respostas para as seguintes questões da pesquisa focadas nos alunos protagonistas participantes: Como o uso do podcast pode atuar como recurso educacional que contribua positivamente para o gosto e hábito da leitura de textos literários? O uso deste recurso tecnológico é viável à Educação Básica? Os fundamentos teóricos e metodológicos pautaram-se em Eco (1979), Lèvy (1996, 2010), Castells (2012), Nóvoa (2010) e Kenski (2004, 2015) quanto às transformações comunicacionais e tecnológicas do Século XX e as mudanças na educação e, em Freire (2012, 2013, 2015) no que se refere ao conceito educacional de podcast. A pesquisa-ação evidenciou a construção do conhecimento de forma colaborativa por meio da tecnologia educacional a partir da mediação da professora-pesquisadora, com uso do ciberespaço e influência da cibercultura. Para a produção dos dados foram utilizados como instrumentos o podcast, os produtos gerados pelos alunos protagonistas (reconto da obra literária, pod-novela, meta-podcasts e podcast de registro), questionário estruturado aplicado aos alunos beneficiados e observações da professora-pesquisadora. Constatou-se que o uso de tal ferramenta tecnológica no contexto da Educação Básica, gerou benefícios quanto ao ensino e aprendizagem de Literatura junto aos alunos protagonistas que, de modo cooperativo, confirmam que a criação do podcast contribui para fluência, gosto e hábito da leitura, aprimoramento quanto ao ato de ler e falar em público, aprofundamento dos conhecimentos voltados aos tipos textuais trabalhados (novela de cavalaria, resenha) assim como dos processos de escrita (reescrita/síntese), além do desenvolvimento da criticidade dos mesmos, poisperceberam que a pod-novela não substitui a obra, mas instiga sua leitura. Verificou-se que o podcast teve boa aceitação entre os alunos protagonistas, a ferramenta educacional apresentou certa facilidade quanto ao uso, financeiramente viável e em consonância com a Educação Tecnológica e o Ensino de Literatura na Educação Básica; no entanto, há necessidade de que o professor haja conforme o novo contexto educacional e tecnológico propõe – que gerencie habilidades e estimule a participação colaborativa de seus estudantes.
MAPEAMENTO DA PRODUÇÃO CIENTÍFICA SOBRE O EXERCÍCIO DE PROFESSORES HOMENS NA EDUCAÇÃO INFANTIL (2010-2020)
Authors: Silva Marciano Antonio , Carvalho Laje Allene
Published: January 2023

Este artigo trata das produções científicas que versam acerca do exercício de professores homens no contexto da Educação Infantil. Utilizamos como banco de dados, a Biblioteca Digital Brasileira de Teses Dissertações – BDTD, mais especificamente, as pesquisas defendidas no período de 2010-2020. Elencamos como objetivo geral do nosso estudo: mapear a produção do conhecimento sobre o exercício de professores homens na Educação Infantil. O percurso metodológico se encontra ancorado na abordagem qualitativa, onde fazemos um estudo do tipo bibliográfico, através da modalidade caracterizada como Estado da Arte. Tecer um olhar para a produção do conhecimento sobre professores homens na Educação Infantil, surge na perspectiva de investigar os principais desafios, enfrentamentos e tabus que cercam os docentes homens que atuam nessa etapa da Educação Básica, mas, também, de denunciar os quadros de machismo, sexismo e LGBTfobia que tem sido reproduzido nesses espaços. Nossas considerações apontam para a emergência de novos estudos em torno das experiências docentes de professores homens que atuam no contexto da Educação Infantil, tendo em vista que essa realidade vem sendo pouco explorada no âmbito das pesquisas acadêmicas.