bluuebunny/crossref_metadata_2025 huggingface dataset:
El desafío de la carrera de Licenciatura en Enfermería frente a las demandas sociales
Authors: Cabrera Verónica Valeria , Ciccarelli Lorena Guadalupe , Saravia Silvio Damián
Published: March 2017

La universidad, desde sus comienzos, es reconocida como institución de primer orden en la transferencia del conocimiento científico y profesional. Se entiende que es un agente fundamental de la innovación atravesada por el contextosociopolítico y económico que da respuestas a las necesidades de los habitantes.Para mantenerse a la par de las aceleradas reformas y cambios que se producen en la comunidad y en el ejercicio de la profesión, la formación en la carrera de Licenciatura en Enfermería debe gestionar cambios curriculares significativos,como en el área del conocimiento, producción, organización y divulgación.Cuestiones que se plantean al momento del proceso de acreditación por parte de la Comisión Nacional de Evaluación y Acreditación Universitaria (CONEAU).En este artículo se reflexionará sobre los desafíos que tiene la carrera de Licenciatura en Enfermería para lograr la integración de los tres principales pilares de la universidad (docencia, investigación y extensión universitaria).
THE INFLUENCE OF BUSINESS RISK TOWARD CAPITAL ADEQUACY RATIO (CAR) ON FOREIGN EXCHANGE NATIONAL PRIVATE COMMERCIAL GO PUBLIC BANKS
Authors: Anggraeni Anggraeni
Published: March 2017

The purpose of the research is to determine LDR, IPR, NPL, APB, IRR, PDN, FBIR, and BOPO simultaneously and partially have significant influence toward Capital Adequacy Ratio (CAR).Population were the foreign Exchange National Private Commercial Go Public Banks. Sampling technique is purposive sampling so that the selected Bank were Himpunan Saudara 1906, Ekonomi Raharja and bank Mayapada International. Data collected by the methods of documentation and analysis were performed by linear multiple regression analysis technique.Results shows that LDR, IPR, NPL, APB, IRR, PDN, FBIR And BOPO simultaneously have significant effect toward Capital Adequacy Ratio (CAR) ratio on foreign Exchange National Private Commercial Go Public Banks. Partially BOPO ratio significantly has a negative effect on Capital Adequacy Ratio (CAR) ratio. Meanwhile LDR, IPR, NPL, IRR and FBIR has a possitive effect but insignificant toward CAR ratio On foreign Exchange National Private Commercial Go Public Banks. On the other side APB and PDN have negative effect but insignificant toward CAR ratio on foreign Exchange National Private Commercial Go Public Banks.
OBSERVASI TREN PERILAKU PEMBELIAN HIJAU KONSUMEN INDONESIA DI BERBAGAI INDUSTRI
Authors: Hiqmah Faizatul
Published: March 2017

Peningkatan kesadaran masyarakat Indonesia terkait dengan gaya hidup ramah ling-kungan telah mendorong berbagai industri untuk merevolusi produk dan layanan agar sesuai dengan transformasi gaya hidup masyarakat Indonesia. Banyak penelitian menguji perilaku pembelian produk ramah lingkungan yang telah dilakukan oleh ba-nyak perusahaan dalam berbagai industri. Namun demikian, penelitian terhadap trend perilaku pembelian atas produk ramah lingkungan atas bermacam industri belum dilakukan. Artikel ini mencoba memahami strategi pemasaran ramah lingkungan yang diterapkan oleh banyak perusahaan dari berbagai industri dan trend perilaku pembe-lian ramah lingkungan secara menyeluruh atas produk atau layananan yang ditwar-kan oleh industri-industri tersebut. Artikel ini juga mencoba mengajukan strategi pemasaran besar untuk produk ramah lingkungan yang bisa diterapkan oleh berbagai industri untuk konsumen Indonesia. Kemampuan untuk mengkaji perilaku pembelian produk ramah lingkungan di Indonesia secara keseluruhan akan sangat bermanfaat karena Indonesia memiliki segmen pasar yang sangat luas. Artikel ini juga berguna untuk menciptakan satu pandangan atas strategi besar pemasaran produk ramah ling-kungan yang bisa diimplementasikan oleh bermacam industri yang menjual atau be-rencana untuk memasarkan produk ramah lingkungan di Indonesia.
Anti-nociceptive and antipyretic activities of Solanum violaceum ortega
Authors: Karim Afroz , Islam Baharul , Tareq Syed , Islam Muhammad
Published: March 2017

Solanum violaceum Ortega has been used by the traditional medicine practitioners in pain and fever. This study aimed at investigating anti-nociceptive and antipyretic activities of methanol extract of leaf (MELSV), fruit (MEFSV) and root (MERSV) of S. violaceum in Swiss albino mice. Anti-nociceptive activity was evaluated using hot plate method while antipyretic by brewer’s yeast induced hyperpyrexia. In both tests, test animals were divided into eight groups of six in each. The groups were treated as negative control (distilled water), standard and tests (250 and 500 mg/kg of MELSV/ MERSV/ MERSV). Diclofenac sodium (150 mg/kg) and paracetamol (150 mg/kg) were taken as standards for anti-nociceptive and antipyretic tests, respectively. All the treatments were administrated via oral gavages (p.o.). Results suggest that, the plant extracts dose-dependently increased retention time compared to the control groups. MELSV at 500 mg/kg significantly increased retention time on the hot-pate of the test animals than the MEFSV and MERSV treated groups. In the antipyretic test, both 250 and 500 mg/kg of MELSV and 500 mg/kg of MEFSV significantly (p <0.05) decreased temperature to the experimental animals 30, 60, 120 minutes. In conclusion, the crude extracts of S. violaceum exhibited anti-nociceptive and antipyretic activities. S. violaceum may be one of the good sources of anti-nociceptive and antipyretic compounds.
The 1000 lumbar spine radiograph study
Authors: Pullicino Glorianne , Pavia Jessica , Sciortino Paul , Chilmeran Ahmed , Sciortino Philip , Pullicino Richard
Published: March 2017

Magnetic resonance imaging is being increasingly used to optimize the diagnostic process for low back pain and to manage the risk of missing life-threatening pathology. The aim of the study was to examine the care pathway of low back pain with respect to the utilisation of CT and MRI service utilisation. A descriptive, retrospective, cross-sectional study was performed. A random sample of 1000 primary care patients presenting with low back pain who underwent lumbar spine radiography within a specified period was explored. 20% (n=198) of patients who underwent lumbosacral spine X-ray were referred for MRI investigation. Subsequently, 15 (7.6%) patients underwent joint infiltration whilst 6 (3%) patients underwent neurosurgical intervention during 2 years of follow-up. Such findings provide information for policy makers about the utility of MRI and CT scans.
The 1807 edition of The Book of the Duchess
Authors: Marshall Simone Celine
Published: March 2017

The 124-volume edition of The Poets of Great Britain, containing The Poetical Works of Geoffrey Chaucer, came into being when, in 1807, a group of thirty-three London booksellers began publication of a work that claims, from its title page, to be a reprint of John Bell’s 1782 series The Poets of Great Britain. The reality, however, is somewhat different. In fact the works of Chaucer have been markedly revised and re-edited, a feature that until now had not been noted by scholars.The following article is a textual analysis of some of the most striking features to have emerged from an analysis of the 1807 edition of The Book of the Duchess, as compared with its predecessors. The Book of the Duchess has been chosen as a sample text for this consideration, primarily because it is of sufficient scope to offer, on the one hand, a substantial enough sample from which to draw conclusions, and, on the other hand, limited enough to be manageable. In addition to these particular reasons, The Book of the Duchess is a poem the authority of which has never been questioned, and thus it has appeared in every printed edition of the works of Chaucer, providing this study with extensive points for comparison.
The Long Game: Five Years of Simulating the Middle East
Authors: Hardy Mat , Totman Sally
Published: March 2017

Scholarly literature attesting to the benefits of role play in teaching International Relations or Political Science subjects is abundant and universally positive. However, despite many case studies presenting snapshots of single examples, long term data concerning a role play exercise is difficult to find. This study presents student feedback data gathered from ten iterations of the Middle East Politics Simulation carried out over five years from 2011-15. The data obtained from hundreds of respondents establishes very clear trends in terms of satisfaction, engagement and workload. The findings demonstrate that students can be significantly engaged in the subject matter through role plays and that they value these opportunities and the learning that ensues, even though it may represent more work than they are used to allotting to traditional assignments. The results show that year after year, successive student cohorts have made a clear judgement that extra work is worthwhile when it pays off against their perceived learning. The inference can also be drawn that they do not see this same pay off when completing essay type assignments.
What do students think about SNS in education? University students’ perceptions, expectations and concerns regarding educational uses of SNS
Authors: AKÇAYIR Murat
Published: March 2017

Social network sites (SNS) have become a popular technology topic in recent years and are currently used in educational environments. Although SNS have attracted much scholarly attention, students’ experiences with and expectations about SNS uses in education have not been deeply explored. This study investigates educational uses of SNS by analyzing university students’ perceptions, experiences, expectations, and concerns. A mixed method approach was used. The participants were 206 Turkish university students aged 18-28. As a quantitative data collection tool, “the social networking use survey” was employed. To better understand the students’ perceptions, expectations, and concerns about using SNS for educational purposes, face-to-face semi-structured interviews were conducted with 58 participants. The results of the study reveal that the students actively used SNS for different purposes. The participants also exhibited positive perceptions of SNS use for educational purposes. Among the biggest expectations is that instructors would share materials using SNS. When the students’ general expectations were examined, notably different results were obtained. The greatest concern of the students was that their posts could be seen by their instructors. All of the research findings are discussed in a detailed manner.
Learning number sense through digital games with intrinsic feedback
Authors: Laurillard Diana
Published: March 2017

The paper proposes a new interdisciplinary approach to helping low attaining learners in basic mathematics. It reports on the research-informed design and user testing of an adaptive digital game based on constructionist tasks with intrinsic feedback. The approach uses findings from the neuroscience of dyscalculia, cognitive science research on conceptual understanding in mathematics, and mathematical education research to inform the detailed pedagogic design. It is interdisciplinary in the sense that it synthesises the results from multiple disciplines in the design principles. It then exploits the new capabilities of digital technologies to develop the design for testing with learners, and capturing appropriate data. The initial pilot has shown that the game supports learners age 5-7 years for independent learning of the kind that low attaining learners will need in order to keep pace with mainstream learners. The experimental work will evaluate this and similar games for learners of all ages who have low numeracy. In general, the approach is to (i) focus on a problem at the intersection of robust evidence in both education and neursocience; and (ii) use this data to design and test a digital intervention that fully exploits the adaptive and interactive features of learning technology.
Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii
Authors: Talman William T. , Dragon Deidre Nitschke , Lin Li‐Hsien
Published: March 2017

Saporin (SAP) or SAP conjugates injected into the nucleus tractus solitarii (NTS) of rats kill astrocytes. When injected in its unconjugated form, SAP produces no demonstrable loss of or damage to local neurons. However bilateral injections of SAP significantly attenuate responses to activation of baroreceptor reflexes that are mediated by transmission of signals through glutamate receptors in the NTS. We tested the hypothesis that SAP would reduce cardiovascular responses to activation of NTS glutamate receptors despite its recognized ability to spare local neurons while killing local astrocytes. In animals treated with SAP and SAP conjugates or, as a control, with the toxin 6‐hydroxydopamine (6‐OHDA), we sought to determine if dose‐related changes of arterial pressure (AP) or heart rate (HR) in response to injection into NTS of N‐methyl‐d‐aspartate (NMDA) or α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) were attenuated. Also we quantified changes in immunoreactivity (IR) for EAAT2, EAAC1, and VGluT2 in NTS after SAP and SAP conjugates. Our earlier studies showed that IR for NMDA and AMPA receptors was not changed after injection of SAP. We found that EAAT2 and EAAC1, both found in astrocytes, were reduced by SAP or its conjugates but not by 6‐OHDA. In contrast, VGluT2‐IR was increased by SAP or conjugates but not by 6‐OHDA. AP and HR responses to NMDA and AMPA were attenuated after SAP and SAP conjugate injection but not after 6‐OHDA. Results of this study are consistent with others that have shown interactions between astroglia and neurons in synaptic transmission mediated by glutamate receptor activation in the NTS.
Aldosterone does not alter endothelin B receptor signaling in the inner medullary collecting duct
Authors: Ramkumar Nirupama , Stuart Deborah , Yang Tianxin , Kohan Donald E.
Published: March 2017

Recent studies suggest that aldosterone‐mediated sulfenic acid modification of the endothelin B receptor (ETB) promotes renal injury in an ischemia/reperfusion model through reduced ETB‐stimulated nitric oxide production. Similarly, aldosterone inactivation of ETB signaling promotes pulmonary artery hypertension. Consequently, we asked whether aldosterone inhibits collecting duct ETB signaling; this could promote fluid retention since CD ETB exerts natriuretic and diuretic effects. A mouse inner medullary collecting duct cell line (IMCD3) was treated with aldosterone for 48 h followed by sarafotoxin‐6c, an ETB‐selective agonist, and extracellular signal‐related kinase 1/2 (ERK) phosphorylation assessed. S6c increased the phospho/total‐ERK ratio similarly in control and aldosterone‐treated cells (aldosterone alone increased phospho/total‐ERK). Since cultured IMCD cell lines lack ETB inhibited AVP signaling, the effect of S6c on AVP‐stimulated cAMP in acutely isolated IMCD was assessed. Rats (have much higher CD ETB expression than mice) were exposed to 3 days of a normal or low Na+ diet, or low Na+ diet + desoxycorticosterone acetate. S6c inhibited AVP‐stimulated cAMP in rat IMCD by the same degree in the high mineralocorticoid groups compared to controls. Finally, S6c‐stimulated cGMP accumulation in cultured IMCD, or S6c‐stimulated nitric oxide or cGMP in acutely isolated IMCD, was not affected by prior aldosterone exposure. These findings provide evidence that aldosterone does not modify ETB effects on ERK phosphorylation, AVP‐dependent cAMP inhibition, or NO/cGMP accumulation in the IMCD. Thus, while aldosterone can inhibit endothelial cell ETB activity to promote hypertension and injury, this response does not appear to occur in the IMCD.
Towards the Establishment of an International Constitutional Court
Authors: Nasrawin Laith K
Published: March 2017

This article comprehensively examines the 1999 recommendation of the Tunisian government to create an International Constitutional Court that is designed to enhance the principles of democracy and human rights and to strengthen the constitutional doctrine which states that the people are the source of authority in a given country. This proposal, which was strongly advocated by former Tunisian President Mohamed Moncef Marzouki during his term in office, aims to underscore the importance of establishing an international judicial entity and analysing its bylaws with respect to its terms and conditions, formation, jurisdiction and selection of judges. The article traces the trajectory of the movement, from the proposal stage to the latest developments in formally establishing the international judicial entity. Finally, the article identifies various possible difficulties and challenges that are likely to stand in the way of implementing the proposal.
Understanding misunderstandings. Presuppositions and presumptions in doctor-patient chronic care consultations
Authors: Macagno Fabrizio , Bigi Sarah
Published: March 2017

Pragmatic presupposition is analyzed as grounded on an implicit reasoning process based on a set of presumptions, which can define cultural differences. The basic condition for presupposing a proposition is represented as a reasoning criterion, namely reasonableness. Presuppositions, on this view, need to be reasonable, namely they need to be the reasonable conclusions of an underlying presumptive reasoning, which does not or may not contain contradictions with other presumptions. Presumptions are in turn analyzed considering their nature and their hierarchy, namely their subject matter and their possible contextual backing, which eliminates some of their possible defaults. This analysis of presupposition brings to light the relationship between misunderstandings deriving from presuppositional failures and the underlying system of presumptions. This approach is applied to the investigation of communicative issues within the medical context, and more precisely doctor-patient communication in diabetes cases.
The Effect of Pulsed Injection on Supersonic Shear Layer Mixing in a Scramjet Combustor
Authors: Smith Leslie , Farokhi Saeed
Published: March 2017

A novel injector has been designed and cold flow injection tests were performed in a modified supersonic wind tunnel. To complement these experimental studies three dimensional STAR-CCM+CFD simulations were developed. The pulse width may be varied, with options of injecting gas for 33 %, 50 % and 66 % of the injection period. The scramjet combustor environment is simulated in a supersonic wind tunnel through a backward facing step for secondary injection purposes and a 157.5 cm (62-inch) long test section. The gas in secondary injection is carbon dioxide and the primary flow is air. The simulations show a coupled interaction between the forcing from injection and the shear layer. Steady state static pressure measurements on the lower wall of the wind tunnel test section agree well with the simulated static pressure along the lower wall. The pulse width strongly impacts shear layer reattachment on the lower wall and varies between 2.4 and 4.3 step heights. Reduction in duty cycle from 66 % to 33 % at 1 kHz caused ~30 % reduction in the shear layer reattachments distance, which points to large scale mixing enhancement.
Compartmentalized cGMP Responses of Olfactory Sensory Neurons inCaenorhabditis elegans
Authors: Shidara Hisashi , Hotta Kohji , Oka Kotaro
Published: March 2017

Cyclic guanosine monophosphate (cGMP) plays a crucial role as a second messenger in the regulation of sensory signal transduction in many organisms. In AWC olfactory sensory neurons ofCaenorhabditis elegans, cGMP also has essential and distinctive functions in olfactory sensation and adaptation. According to molecular genetic studies, when nematodes are exposed to odorants, a decrease in cGMP regulates cGMP-gated channels for olfactory sensation. Conversely, for olfactory adaptation, an increase in cGMP activates protein kinase G to modulate cellular physiological functions. Although these opposing cGMP responses in single neurons may occur at the same time, it is unclear how cGMP actually behaves in AWC sensory neurons. A hypothetical explanation for opposing cGMP responses is region-specific behaviors in AWC: for odor sensation, cGMP levels in cilia could decrease, whereas odor adaptation is mediated by increased cGMP levels in soma. Therefore, we visualized intracellular cGMP in AWC with a genetically encoded cGMP indicator, cGi500, and examined spatiotemporal cGMP responses in AWC neurons. The cGMP imaging showed that, after odor exposure, cGMP levels in AWC cilia decreased transiently, whereas levels in dendrites and soma gradually increased. These region-specific responses indicated that the cGMP responses in AWC neurons are explicitly compartmentalized. In addition, we performed Ca2+imaging to examine the relationship between cGMP and Ca2+. These results suggested that AWC sensory neurons are in fact analogous to vertebrate photoreceptor neurons.

SIGNIFICANCE STATEMENTCyclic guanosine monophosphate (cGMP) plays crucial roles in the regulation of sensory signal transduction in many animals. In AWC olfactory sensory neurons ofCaenorhabditis elegans, cGMP also has essential and distinctive functions involving olfactory sensation and adaptation. Here, we visualized intracellular cGMP in AWC neurons with a genetically encoded cGMP indicator and examined how these different functions could be regulated by the same second messenger in single neurons. cGMP imaging showed that, after odor application, cGMP levels in cilia decreased transiently, whereas levels in dendrites and soma gradually increased. These region-specific responses indicated that the responses in AWC neurons are explicitly compartmentalized. In addition, by combining cGMP and Ca2+imaging, we observed that AWC neurons are analogous to vertebrate photoreceptor neurons.
CREB Signaling Is Involved in Rett Syndrome Pathogenesis
Authors: Bu Qian , Wang Anxin , Hamzah Hamdi , Waldman Alex , Jiang Keer , Dong Qiping , Li Ronghui , Kim Jason , Turner Daniel , Chang Qiang
Published: March 2017

Rett syndrome (RTT) is a debilitating neurodevelopmental disorder caused by mutations in theMECP2gene. To facilitate the study of cellular mechanisms in human cells, we established several human stem cell lines: human embryonic stem cell (hESC) line carrying the common T158M mutation (MECP2T158M/T158M), hESC line expressing no MECP2 (MECP2-KO), congenic pair of wild-type and mutant RTT patient-specific induced pluripotent stem cell (iPSC) line carrying the V247fs mutation (V247fs-WT and V247fs-MT), and iPSC line in which the V247fs mutation was corrected by CRISPR/Cas9-based genome editing (V247fs-MT-correction). Detailed analyses of forebrain neurons differentiated from these human stem cell lines revealed genotype-dependent quantitative phenotypes in neurite growth, dendritic complexity, and mitochondrial function. At the molecular level, we found a significant reduction in the level of CREB and phosphorylated CREB in forebrain neurons differentiated fromMECP2T158M/T158M,MECP2-KO, and V247fs-MT stem cell lines. Importantly, overexpression of CREB or pharmacological activation of CREB signaling in those forebrain neurons rescued the phenotypes in neurite growth, dendritic complexity, and mitochondrial function. Finally, pharmacological activation of CREB in the femaleMecp2heterozygous mice rescued several behavioral defects. Together, our study establishes a robustin vitroplatform for consistent quantitative evaluation of genotype-dependent RTT phenotypes, reveals a previously unappreciated role of CREB signaling in RTT pathogenesis, and identifies a potential therapeutic target for RTT.

SIGNIFICANCE STATEMENTOur study establishes a robust human stem cell-based platform for consistent quantitative evaluation of genotype-dependent Rett syndrome (RTT) phenotypes at the cellular level. By providing the first evidence that enhancing cAMP response element binding protein signaling can alleviate RTT phenotypes bothin vitroandin vivo, we reveal a previously unappreciated role of cAMP response element binding protein signaling in RTT pathogenesis, and identify a potential therapeutic target for RTT.
A single night light exposure acutely alters hormonal and metabolic responses in healthy participants
Authors: Albreiki Mohammed S , Middleton Benita , Hampton Shelagh M
Published: March 2017

Many animal studies have reported an association between melatonin suppression and the disturbance of metabolic responses; yet, few human studies have investigated bright light effects on metabolic and hormonal responses at night. This study investigated the impact of light on plasma hormones and metabolites prior to, and after, an evening meal in healthy participants. Seventeen healthy participants, 8 females (22.2 ± 2.59 years, mean ± s.d.) and 9 males (22.8 ± 3.5 years) were randomised to a two-way cross-over design protocol; dim light (DL) (<5 lux) and bright light (BL) (>500 lux) sessions, separated by at least seven days. Saliva and plasma samples were collected prior to and after a standard evening meal at specific intervals. Plasma non-esterified fatty acid (NEFA) levels were significantly higher pre-meal in DL compared to BL (P < 0.01). Plasma glucose and insulin levels were significantly greater post-meal in the BL compared to DL session (P = 0.02, P = 0.001), respectively. Salivary melatonin levels were significantly higher in the DL compared to those in BL session (P = 0.005). BL at night was associated with significant increases in plasma glucose and insulin suggestive of glucose intolerance and insulin insensitivity. Raised pre-prandial NEFA levels may be due to changes in insulin sensitivity or the presence of melatonin and/or light at night. Plasma triglyceride (TAG) levels were the same in both sessions. These results may explain some of the health issues reported in shift workers; however, further studies are needed to elucidate the cause of these metabolic changes.
New LC–UV methods for pharmaceutical analysis of novel anti-diabetic combinations
Authors: Abdel-Ghany Maha F. , Abdel-Aziz Omar , Ayad Miriam F. , Tadros Mariam M.
Published: March 2017

New, simple, selective, and sensitive liquid chromatography–ultraviolet (LC–UV) methods have been developed and subsequently validated for simultaneous determination of linagliptin–empagliflozin combination and simultaneous determination of alogliptin benzoate–pioglitazone hydrochloride combination. Linearity was found to be acceptable over the concentration ranges of 2–50 μg mL−1, 4–100 μg mL−1, 0.5–25 μg mL−1, and 1–25 μg mL−1 for linagliptin (LNG), empagliflozin (EMG), alogliptin (ALG), and pioglitazone (PGN), respectively. All the methods were applied successfully to the analysis of the pharmaceutical dosage forms. The optimized methods were validated and proved to be robust and accurate for the quality control of the mentioned drugs in their different pharmaceutical dosage forms.
Komplementer terápiás gyógymódok megítélése a perioperatív ellátásban dolgozó egészségügyi szakdolgozók között
Authors: Soós Sándor Árpád , Jeszenői Norbert , Darvas Katalin , Harsányi László
Published: March 2017

Abstract:

Introduction: Perioperative healthcare professionals’ attitudes towards non-conventional treatments have not been explored in Hungary yet. Aim: Our goal was to survey healthcare professionals’ attitude and knowledge towards naturopathy in six clinics of the Semmelweis University that provide perioperative care. Method: An anonymous, paper-based questionnaire was used. With an 82% response rate, the data was gained from 119 questionnaires and was processed using statistical analysis and chi-squared test. Results: Only 25.2% of those surveyed considered themselves to be well-informed in this field. 68.1% of the participants had an interest in naturopathy and 60.5% would have liked to learn about naturopathy. 70.6% would be willing to use non-conventional treatments in their daily work, predominantly those who have used these methods in the case of their own illness, p = 0.0027. The most popular treatment methods included homeopathy, alternative massage and movement therapy, acupuncture and manual therapy. Conclusion: As anticipated based on international literature in this field, those Hungarian healthcare professionals who took part in our survey showed openness and interest towards naturopathy. Orv. Hetil., 2017, 158(10), 368–375.
Prawa i obowiązki wiernych ze szczególnym uwzględnieniem praw i obowiązków rodziny
Authors: Kornecki Tomasz
Published: March 2017

The members of the Catholic Church have both rights and responsibilities, which result from the nature of the human being, as people are called to follow their vocation in life. However, to make it possible people and their activities must be protected by the rights and duties. Code of Canon Law sets out the rights and responsibilities of those who believe. It should be emphasized that these rights and duties permeate each other. A human being, as a member of the community of the Church through baptism, has the right, but also the obligation to promote holiness in life and thus strive to achieve it, since not only does it enrich inner life, but it also affects family life making it more human and more Christian. Parents should enjoy the right to educate their children according to their own beliefs and systems of values, and the state authorities cannot infract or destroy these systems. The right to education is a part of the idea of evangelization, which should originate from the closest members of a family. At the same time members of the Church, including both parents and children, can rely on help from the clergy in achieving salvation. They have the right to form associations and the right to defend the good name.
The Primary Metatarsalgia: Pathogenesis, Biomechanics and Surgical Treatment
Authors: Bobrov D. S. , Slinjakov L. J. , Rigin N. V.
Published: March 2017

This paper presents a comprehensive review on the current concept of the diagnosis and treatment of central metatarsalgia on the basis of medical literature analyses. Metatarsalgia is the term for pain in the forefoot. This is a set of symptoms corresponding to a wide range of diseases. Central metatarsalgia is a kind of metatarsalgia which arises from structural-functional changes that lead to excessive pressure in the area of metatarsal heads. The data analysis demonstrated that presently various types of osteotomies of metatarsal bones are the main surgical treatment options with the chance of complication ranging from 6 to 50%. Weil-osteotomy is known to be the most popular type of osteotomy for treatment of central metatarsalgia. The most common complication of Weil-osteotomy is floating toe, the one that doesn’t contact with the supporting surface. In case Weil-osteotomy and intraphalangeal arthrodesis with trans acticular fixation are both performed, the complication of floating toe increases up to 50%. When Weil osteotomy, plantar plate repair, extensor digitorum longum tendon lengthening and triple Weil-osteotomy are performed simultaneously, the complication rate is 15% approximately which is much lower. Using combined osteotomy techniques as well as taking into account structural-functional pathologic changes of the forefoot and ligaments repair of metatarsalphalangeal joint will ensure the most successful development of surgical treatment techniques for central metatarsalgia.
Urethra Reconstruction with Tissue-Engineering Technology
Authors: Vasyutin I. A. , Lyundup A. V. , Vinarov A. Z. , Butnaru D. V. , Kuznetsov S. L.
Published: March 2017

Urethral stricture is a disease characterized by a pathological narrowing of the urethra. Treatment for this condition often requires surgery using autologous grafts (urethroplasty). It is common practice to use patient’s own tissue like genital and extragenital skin, tunica vaginalis, buccal mucosa as a source of the graft. Alternative and safer approach is to use tissue-engineered graft created in a laboratory using patient’s autologous cells and biocompatible matrix (scaffold). The article presents the up-to-date achievements in lab-created tissue-engineered graft, describes all components needed to build a tissue-engineered structure of the graft for urethroplasty, and summarizes authors’ thoughts on advantages and disadvantages of various approaches to choose both cellular component and the matrix of future construction. The article reviews clinical studies conducted in the field of tissue engineering of the graft material for urethraplasty.
Prospects for the Use of Cannabinoid Receptor Ligands for the Treatment of Metabolic Syndrome and Atherosclerosis: Analysis of Experimental and Clinical Data
Authors: Maslov L. N. , Karpov R. S.
Published: March 2017

An antagonist of central cannabinoid CB1 receptors rimonabant causes weight loss in patients with obesity and metabolic syndrome, improves blood lipid parameters, increases the adiponectin level, decreases the rate of glucose and glycosylated hemoglobin in patients with diabetes mellitustype-2. However, rimonabant adverse effects include depression, anxiety, nausea, and dizziness which are apparently due to the blockade of central CB1 receptors. In mice with a high-calorie diet, we defined that the blockade of peripheral CB1 receptors prevents obesity, steatosis of the liver, improves lipid and carbohydrate metabolism. Experimental studies suggest that peripheral CB2 receptor agonists have antiatherogenic effect. To validate the expediency of clinical research of CB2 receptor agonists in patients with atherosclerosis the comparative analysis of antiatherogenic properties of cannabinoids should be performed. In addition, experiments are needed on the combination use of cannabinoids with well-known antiatherogenic agents, such as statins.
D.I. Ivanovsky ― A Pioneer Discover of Viruses, As A New Form of Biological Life
Authors: Zhirnov O. P. , Georgiev G. P.
Published: March 2017

125 years ago, in 1992, a Russian scientist Dmitri Iosifovich Ivanovsky published first research data disclosing a unique form of filterable biological microlife. Further scientific progress in this discovery resulted in a new discipline of human knowledge, called «the Kingdom of viruses».A fundamental understanding of viral form of biological life was established not at once and was gradually formed under the accumulation of scientific facts. Only at the beginning of 50 years of the twentieth century, a basic understanding of viral Kingdom had been formed and 1992 year was recognized as the year of the birth of Virology. Virology, which started developing by the research of D.I. Ivanovsky, gave remarkable progress and prominent results: more than 20 scientists got Nobble Prize for the outstanding works in virology. There are all arguments and grounds to nominate the international scientific award in virology named of D.I. Ivanovsky.
Mentorship in Modern UK Surgical Training
Authors: Stewart Heather , Iskander Morkos
Published: March 2017

This article was migrated. The article was marked as recommended. Over the years, surgical training has been standardised and centralised with less emphasis on a mentorship style of training. However, having a consistent mentor during surgical training can overcome obstacles faced by trainees. It has been shown to improve career success as well as general well-being in a demanding and competitive specialty. Despite this, a mentor is not a mandatory part of surgical training with trainees struggling to identify a mentor in the present system. We suggest the introduction of a programme managed by regional deaneries which promotes the formation of a mentor and trainee relationship at the beginning of surgical training. We are confident this scheme has the potential of producing a technically able, healthy and well-rounded surgeon.
Qualitative analysis of the Clock Drawing Test by educational level and cognitive profile
Authors: Fabricio Aline Teixeira , Aprahamian Ivan , Yassuda Mônica Sanches
Published: March 2017

The use of a qualitative scale for the Clock Drawing Test (CDT) may add information about the pattern of errors committed. Objective: To translate and adapt the Modified Qualitative Error Analysis of Rouleau into Brazilian Portuguese and to examine the pattern of errors according to educational level and cognitive profile. Method: 180 adults (47-82 years) completed the CDT. Participants were stratified into age and educational levels and separated between those with and without changes in cognitive screening tests (Mini-Mental State Examination, Verbal Fluency). Results: No significant differences were found in CDT scores among age groups. Among participants without cognitive impairment, those with lower education often presented graphic difficulties, conceptual deficits and spatial deficits. Participants with cognitive deficits, demonstrated more frequently conceptual and spatial errors. Conclusion: The qualitative analysis of the CDT may contribute to the identification of cognitive changes. Education level has to be taken into consideration during the analysis.
Complete removal of the spinal nerve sheath tumors. Surgical technics and results from a series of 30 patients
Authors: Fernandes Rudi Lenck , Lynch José Carlos , Welling Leonardo , Gonçalves Mariangela , Tragante Rodrigo , Temponi Vicente , Pereira Celestino
Published: March 2017

Objective: Observe whether a microsurgical gross total removal (GTR) of a spinal nerve sheath tumors (SNSTs) is safe and decreases the tumor recurrence. Method: We identify 30 patients with 44 SNSTs. Results: We operated upon 15 males and 15 females patients; mean age 40 years. GTR was achieved in 29 (96.6%) instances. Surgical mortality was 3.3% and the recurrence rate was 3.3%. The median follow-up time was 6.2 years. Conclusion: The surgical approach used in this group of patients afford that the great majority of tumors could be totally removed with low mortality and low recurrence rates, proving to be safe and effective.
De epifania a método: a teopolítica do testemunho em um seminário pentecostal em Gana
Authors: Reinhardt Bruno
Published: March 2017

Resumo Neste artigo, analiso a teopolítica do testemunho em um seminário Pentecostal baseado em Gana. Meu foco etnográfico é o testemunho do fundador da denominação Lighthouse Chapel International, que relata como ele recebeu a sua dádiva para ensinar através de uma impartição (transferência do carisma) midiática. No seminário de sua denominação, essa inusitada epifania transforma-se em um verdadeiro método de impartição: a “saturação em fitas-cassete”. Como pode a experiência carismática, normalmente definida por sua inefabilidade, adquirir o poder de replicação típico dos métodos e das técnicas? Destaco como o problema da autenticação do testemunho é diretamente endereçado pela pedagogia desse seminário através de duas operações discursivas: um enquadramento metapragmático das relações de aprendizado ministerial via figuração bíblica e uma noção êmica de transmissão que articula carisma, mimetismo e repetição de maneira não contraditória. Concluo revisitando a natureza do poder que flui para e através desse líder carismático, tanto em seu testemunho quanto no método que é dele extraído.
Das relações entre Exemplo e Parresia: formas de evangelização católica
Authors: Bonfim Evandro de Sousa
Published: March 2017

Resumo O artigo tem como objetivo articular a questão das modalidades de testemunho, dentro do catolicismo, com as modalidades de veridicção – as formas de dizer a verdade estudadas por Foucault – através da noção de parresia, conceito grego com importantes conotações para a vida pública, que tem sido retomado pela Renovação Carismática como dom do Espírito Santo. A descrição da parresia através de dados etnográficos permitirá a percepção de movimentos de diferenciação interna à Igreja Católica, com a chamada “ousadia no Espírito Santo” estabelecendo relações de oposição e complementaridade com o modelo do exemplo, substituindo-o por atitudes interpelativas que incluem a própria transmissão pneumática, gerando modelos distintos de ação sobre o mundo com conotações políticas.
Testemunho: cristão e secular
Authors: Dullo Eduardo
Published: March 2017

Resumo Em um Centro Social Católico, os jovens bem-sucedidos no processo de inclusão social eram incentivados a oferecer um testemunho de sua trajetória de vida para os outros jovens excluídos. Tal prática era fundamentada na pedagogia de Paulo Freire e visava demonstrar o protagonismo e o “empoderamento” dos jovens. O presente artigo visa explorar uma série de imbricamentos dessa prática do testemunho, mostrando como ele é, ao mesmo tempo, cristão e secular, informativo e performativo, individual e relacional. Concluo que a eficácia do testemunho depende desses imbricamentos, visíveis em sua historicidade (da pedagogia de Freire ao uso contemporâneo) e na sua temporalidade relacional (o passado do narrador é projetado no futuro da audiência), evidenciando a secularidade católica brasileira.
A práxis de Lebret: economia humana, desenvolvimentismo católico e a industrialização do Nordeste
Authors: Godoy José Henrique Artigas de
Published: March 2017

Resumo O estudo do pensamento do padre dominicano francês Louis-Joseph Lebret procura refletir sobre as estratégias desenvolvimentistas formuladas nas décadas de 1950 e 1960 no Brasil. Destaca-se uma linhagem de pensamento católica, pouco estudada na história do pensamento desenvolvimentista no país. O foco na trajetória e na práxis de Lebret, envolvendo a recepção de seu pensamento junto à esquerda católica e às primeiras gerações de urbanistas no Brasil, atenta para a relevância histórica e para a atualidade do pensamento do clérigo. Neste sentido, ressalta-se o relatório sobre a industrialização de Pernambuco, primeiro esforço de planejamento de políticas de desenvolvimento regional e marco inaugural do Complexo Industrial e Portuário de Suape, um dos maiores polos de investimentos industriais da história da região.
Normas de Associação Livre para 1004 Palavras do Português Brasileiro
Authors: Janczura Gerson Américo , Castilho Goiara Mendonça , Keller Victor Nahuel , Oliveira Nelson Rocha
Published: March 2017

RESUMO Normas de associação para 1004 palavras do português brasileiro são apresentadas. Aplicando-se o paradigma da Associação Livre, coletou-se a primeira palavra que viesse à mente dos participantes, evitando-se efeitos de inibição e encadeamento de respostas. Associadas de cada pista foram produzidas por um mínimo de 100 participantes. Oriundos de IES pública e privada, matriculados em 44 cursos, 871 estudantes universitários participaram da coleta. As normas relatam a Força Associativa Direta de todas as associadas, e várias incluem a Força Associativa Reversa. O número de associadas por pista variou de 2 a 26, sendo que as palavras mais fortemente associadas ocuparam as primeiras seis posições associativas. Discutem-se a generalidade e a validade de normas de associação.
Impasses no atendimento e assistência do migrante e refugiados na saúde e saúde mental
Authors: Knobloch Felicia
Published: March 2017

Questões sobre atendimento à saúde são, atualmente, a porta de entrada dos direitos humanos e dos dispositivos de reconhecimento dos migrantes e refugiados. Entretanto, dependendo de como se entende a assistência a esse grupo pode ser gerado um "desreconhecimento" do sujeito. Impasses surgem ao se naturalizar a experiência migratória como fator de risco que leva à patologia psíquica. Quando o discurso sobre imigração é vinculado a formas específicas de sofrimento psíquico, corre-se o risco de medicalização da experiência migratória e controle farmacológico de problemas que podem ser sociais, políticos ou econômicos. Um desafio é a formação de trabalhadores no atendimento à saúde física e mental dos migrantes para dar suporte ao encontro: é necessário compreender a representação da saúde e da doença no contexto de origem e as especificidades atuais de vida dessas pessoas sem estereotipar a condição de migrante ou refugiado nem silenciar a singularidade do sujeito.
Resposta do milho verde à inoculação com Azospirillum brasilense e níveis de nitrogênio
Authors: Araújo Raul Matos , Araújo Ademir Sérgio Ferreira de , Nunes Luís Alfredo Pinheiro Leal , Figueiredo Marcia do Vale Barreto
Published: March 2017

O objetivo deste trabalho foi avaliar o efeito da inoculação com Azospirillum brasilense e adubação nitrogenada sobre a produtividade do milho verde. O estudo foi conduzido no município de Teresina, PI, em 2011 e 2012, e os tratamentos foram dispostos em delineamento de blocos ao acaso sob arranjo fatorial de 5x2, sendo cinco doses de nitrogênio (N) (0, 50, 100, 150 e 200 kg N ha-1) com e sem inoculação. No tratamento com inoculação, foi utilizado um produto formulado contendo A. brasilense, estirpes Abv5 e Abv6. Houve aumento significativo no número e na massa das espigas comerciais com a inoculação de A. brasilense em relação ao tratamento sem inoculação. A combinação de inoculação com A. brasilence e nitrogênio aumenta em mais de 30% a produção de espigas de milho verde.
Growth ring analysis of Euxylophora paraensis through x-ray microdensitometry
Authors: Andrade Eva Santos de , Garcia Silvana dos Santos Carvalho , Albernaz Ana Luisa Kerti Mangabeira , Tomazello Fillho Mario , Moutinho Victor Hugo Pereira
Published: March 2017

ABSTRACT: Euxylophora paraensis Huber - Rutaceae, popularly known as yellow heart, is a species with a low-density population that has suffered intense exploitation in recent decades. This has led to its inclusion in the IBAMA list of endangered species. This study aimed to evaluate the existence of growth rings and their annuity in five trees of Euxylophora paraensis through the x-ray microdensitometry technique, as well as to compare them using the classical method. Application feasibility of this technique can be deepened through future, broader dendroecological studies, which may better elucidate the understanding of the species population dynamics and promote more sustainable uses. Wood disks were collected from the base of five 29-year-old trees from a planting site in the Curua-Una Experimental Station, located in Prainha, Pará State, Brazil. Samples were polished and sanded for the x-ray microdensitometric analysis. Values of minimum, average, and maximum density (0.581, 0.84, and 1.077gcm-3, respectively) were obtained. There was a significant difference in density between the studied trees. Growth rings boundaries, through densitometric pith-bark profile are demarcated by fibrous zones, with density variation between the early wood and late wood. This study concludes that the growth rings of the studied species are distinct and annual, validating the technique used.