bluuebunny/crossref_metadata_2025 huggingface dataset:
Embryo quality and chromosomal abnormality in embryos from couples undergoing assisted reproductive technology using preimplantation genetic screening
Authors: Niusha Mina , Rahmani Seyed Ali , Kohan Leila , Sadeghi Ladan , Nouri Mohammad , Nejabati Hamid Reza
Published: January 2023

Objective:

To detect common chromosomal aneuploidy variations in embryos from couples undergoing assisted reproductive technology and preimplantation genetic screening and their possible associations with embryo quality.

Methods:

In this study, 359 embryos from 62 couples were screened for chromosomes 13, 21, 18, X, and Y by fluorescence insitu hybridization. For biopsy of blastomere, a laser was used to remove a significantly smaller portion of the zona pellucida. One blastomere was gently biopsied by an aspiration pipette through the hole. After biopsy, the embryo was immediately returned to the embryo scope until transfer. Embryo integrity and blastocyst formation were assessed on day 5.

Results:

Totally, 282 embryos from 62 couples were evaluated. The chromosomes were normal in 199 (70.57%) embryos and abnormal in 83 (29.43%) embryos. There was no significant association between the quality of embryos and numerical chromosomal abnormality (P=0.67).

Conclusions:

Embryo quality is not significantly correlated with its genetic status. Hence, the quality of embryos determined by morphological parameters is not an appropriate method for choosing embryos without these abnormalities.
A novel herbal combination ameliorates ovarian dysfunction and regulates altered biochemical parameters in rats with letrozole-induced polycystic ovary syndrome
Authors: Shailajan Sunita , Menon Sasikumar , Singh Swati , Patil Yugandhara
Published: January 2023

Objective:

To investigate the potential activity of novel herbal combination and novel herbal formulation (syrup) in female Sprague Dawley rats with letrozole-induced polycystic ovary syndrome (PCOS).

Methods:

Forty-two rats were randomly divided into seven groups with six rats in each group. Group 1 received 0.5% carboxy methylcellulose orally for 37 days and served as the normal control group. Group 2 was orally administered with letrozole of 1 mg/kg for 21 days and served as the PCOS induction group without treatment. Group 3 to 7 were administered with letrozole of 1 mg/kg for 21 days orally to induce PCOS, and then respectively received clomiphene citrate at 1 mg/kg, 100 and 200 mg/kg of novel herbal combination, 200 mg/kg of novel herbal formulation (syrup), and 400 mg/kg of marketed formulation of Pushyanuga churna, once daily for 15 days. Effects of the novel herbal combination and its syrup formulation were evaluated on the hormonal profile, the levels of antioxidants, the lipid profile and on the ovarian morphology, using letrozole-induced PCOS model in rats.

Results:

Letrozole caused alterations in hormonal levels and lipid levels similar to PCOS and ovarian histology showed presence of ovarian cysts confirming the induction of PCOS in rats. On treatment with the novel herbal combination and its syrup formulation in PCOS-induced rats, the altered hormonal and lipid profiles showed significant recovery to normal levels. Ovarian histology confirmed the restoration of folliculogenesis in the PCOS-induced rats. The treatment with the syrup formulation of novel herbal combination was found to be more effective than novel herbal combination and showed better recovery in various parameters evaluated. The results of the study, however, suggested that treatment with novel herbal combination and its syrup formulation provided minimal protection against oxidative stress caused due to the induction of PCOS.

Conclusions:

The integrated approach for management of PCOS is to counterbalance the limitations associated with modern therapy. Both the novel herbal combination and the syrup formulation of novel herbal combination show efficacy in the management of PCOS in rats and restore folliculogenesis in the ovary. The syrup formulation of novel herbal combination is most effective in the management of PCOS and shows potential to be developed as an adjuvant therapeutic agent.
Effects of N-acetylcysteine on growth, viability and reactive oxygen species levels in small antral follicles cultured in vitro
Authors: Cordeiro Efigênia B. , Silva Bianca R. , Paulino Laís R. F. M. , Barroso Pedro A. A. , Barrozo Laryssa G. , de Lima Neto Miguel F. , Silva José R. V.
Published: January 2023

Objective:

To investigate the effects of different concentrations of N-acetylcysteine on follicular growth and morphology, as well as on viability, levels of reactive oxygen species (ROS) and meiotic progression of oocytes from in vitro cultured bovine early antral follicles.

Methods:

Isolated early antral follicles (about 500 μm) were cultured in TCM-199+ alone or supplemented with 1.0, 5.0 or 25.0 mM N-acetylcysteine at 38.5 °C with 5% CO2 for 8 days. Follicle diameters were evaluated at day 0, 4 and 8 of culture. At the end of culture, the levels of ROS, chromatin configuration and viability (calcein-AM and ethidium homodimer-1 staining) were investigated in the cumulus-oocyte complexes. Comparisons of follicle diameters between treatments were performed. Data on percentages of morphologically normal follicles, growth rates and chromatin configuration in different treatments were compared.

Results:

An increase in follicular diameters after culture in all treatments was observed, except for follicles cultured with 25.0 mM N-acetylcysteine. Fluorescence microscopy showed that oocytes cultured in all treatments were stained positively with calcein-AM, and that 5.0 mM N-acetylcysteine reduced fluorescence for ethidium homodimer-1. Intracellular levels of ROS in oocytes from follicles cultured with 1.0 mM N-acetylcysteine showed a significant reduction compared to other treatments. The presence of N-acetylcysteine in culture medium did not influence the rates of oocyte at the germinal vesicle stage.

Conclusions:

N-acetylcysteine at concentrations of 1.0 and 5.0 mM reduces ROS levels and staining for ethidium homodimer-1 in in vitro cultured follicles, respectively, while 25.0 mM N-acetylcysteine decreases follicular growth and the percentages of continuously growing follicles.
Relationships of body composition and adipocytokines with outcomes in metastatic castration-resistant prostate cancer patients receiving docetaxel chemotherapy
Authors: Li Jun-Hong , Zhang Xing-Ming , Bian Xiao-Jie , Gu Wei-Jie , Wan Fang-Ning , Dai Bo , Ye Ding-Wei
Published: January 2023

We evaluated the relationships of body composition and serum adipocytokine levels with progression-free survival (PFS) and overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC) patients receiving docetaxel. The medical records of mCRPC patients who received docetaxel between January 2011 and December 2015 at Fudan University Shanghai Cancer Center (Shanghai, China) were reviewed. The following body composition parameters were calculated using computed tomography: skeletal muscle index (SMI), visceral adipose tissue index (VATI), and subcutaneous adipose tissue index (SATI). Pretreatment serum adipocytokine levels, including interleukin 6, insulin, leptin, monocyte chemoattractant protein-1, adiponectin, and resistin, were measured using the multiplex bead-based immunoassays. Cox regression and Kaplan–Meier methods were used for survival analyses. Of the 453 mCRPC patients initially identified, 105 were included in the analysis. High VATI group patients had longer PFS (median, 10 months vs 7 months, P = 0.008) and OS (median, 24 months vs 15 months, P = 0.017), compared with low VATI group patients. SMI and SATI were not significantly associated with PFS or OS. Of the six detected adipocytokines, only leptin was associated with mCRPC prognosis. High leptin group patients had shorter PFS (median, 7 months vs 12 months, P = 0.0018) and OS (median, 17 months vs 22 months, P = 0.042), compared with low leptin group patients. Multivariate analysis showed that a high VATI was an independent protective factor for PFS and OS, while a high leptin level was an independent risk factor for PFS and OS. Therefore, VATI and serum leptin levels could provide important information concerning mCRPC prognosis.
Combined Warden and Mustard procedure for late presenting transposition with anomalous pulmonary venous connections and regressed left ventricle
Authors: Subramaniam Ganapathy Krishnan , Gnanasekaran Pradeep , Sharma Dhruva , Shri Ramya , Chandrashekhar Anitha
Published: January 2023

The presence of systemic and pulmonary venous anomalies in late presenting transposition of great arteries (TGA) may make standard atrial switch procedures difficult, necessitating modification in the surgical procedure. We present a case report of a 13-year-old boy with a partial anomalous connection of right superior pulmonary vein with TGA and regressed left ventricle, where a combination of Warden procedure and Mustard procedure was used.
Unknown origin of acute myocardial infarction and lifesaving percutaneous coronary intervention in a 10-year-old girl
Authors: Temel Münevver Tugba , Altunbaş Gökhan , Başpınar Osman
Published: January 2023

Myocardial infarction is extremely rare in children. However, chest pain suspected to be cardiac in origin by the parents is a very common presenting symptom in pediatric emergency services. In this case, an electrocardiogram is very important in the differential diagnosis of cardiogenic complaints and should be carefully considered.
A rare cause of cyanosis in neonatal age
Authors: Caputo Adriano , Giordano Mario , Iacono Carola , Oppido Guido , Russo Maria Giovanna
Published: January 2023

Cor triatriatum dexter is an extremely rare congenital anomaly that is caused by the partitioning of the right atrium by a broad sheet of tissue due to the persistence of the right sinus venosus valve. We describe a rare case of prominent right sinus venosus valve (cor triatriatum dexter) with consequent right-to-left shunt across the patent foramen ovale in a newborn with significant cyanosis.
Assessment of the effect of two regimens of milrinone infusion in paediatric patients with pulmonary artery hypertension undergoing corrective cardiac procedure
Authors: Prajapati Mrugesh , Patel Jigar , Patel Hasmukh , Gandhi Hemang , Singh Guriqbal , Patel Pravin
Published: January 2023

Background :

The aim of the study was to compare the effect of two different regimens of milrinone in pediatric patients with pulmonary artery hypertension (PAH) undergoing corrective procedure.

Materials and Methods :

This randomized prospective study included 100 pediatric patients undergoing corrective cardiac surgeries. Group E: Milrinone was started as infusion 0.5 μg/kg/min without a loading dose after induction of anesthesia and continued as infusion 0.5–0.75 μg/kg/min in the pediatric cardiac surgical intensive care unit (PSICU). Group L: Milrinone was started as a loading dose 50 μg/kg over 10 min before weaning from cardiopulmonary bypass (CPB) followed by infusion 0.5–0.75 μg/kg/min in the PSICU. We compared heart rate, mean arterial blood pressure, central venous pressure, cardiac index (CI), mean pulmonary arterial pressure (MPAP), serum lactate level, urine output, vasoactive inotropic score, mechanical ventilation duration, and intensive care unit (ICU)- and hospital length of stay between the groups.

Results :

There was an increase in mean arterial blood pressure, CI, and urine output in Group E compared to Group L (P < 0.05). MPAP, serum lactate level, and requirement of inotropes and vasopressors were lower in Group E compared to Group L (P < 0.05). Mechanical ventilation duration, ICU, and hospital length of stay were shorter in Group E than Group L (P < 0.05).

Conclusions :

Early use of milrinone in patients with PAH undergoing corrective cardiac surgeries improved CI and mean arterial pressure, decreased MPAP, improved urine output, decreased serum lactate level, and decreased requirement of inotropes and vasopressors after weaning from CPB compared to the milrinone bolus group.
Absent left main coronary artery in a case of pulmonary atresia-intact ventricular septum and right ventricle-dependent coronary circulation
Authors: Krokovay Anna , Knirsch Walter , Kelly-Geyer Janet , Cesnjevar Robert , Dave Hitendu
Published: January 2023

Right ventricle-dependent coronary circulation coexisting with left main coronary atresia in the setting of pulmonary atresia-intact ventricular septum is rare. In the case described, the left coronary artery (LCA) origin from the aorta could not be found on conventional angiography or cardiac magnetic resonance imaging. During surgery, multiple LCA branches originating from the finger-like continuum of the primitive right ventricular sinusoidal network were observed. A Damus–Kaye–Stansel anastomosis and an aortopulmonary shunt operation were performed. Shunt takedown and a bidirectional Glenn anastomosis followed at 3 months of age. At 18 months follow-up, the child is thriving with stable hemodynamics and a saturation of 85%. Awareness about this rare coronary artery anomaly is necessary to prevent catastrophic consequences. The challenges, complications, and lessons learned while treating this rare variant are discussed.
How I do it
Authors: Batlivala Sarosh P. , McGovern Eiméar , Goldstein Bryan H.
Published: January 2023

Congenital portosystemic venous connections are rare vascular anomalies that connect the portal and systemic venous circulations. These vascular lesions can lead to complex and varied physiologic manifestations in single-ventricle patients as they progress through the various stages of palliation in the Fontan pathway. Specifically, these connections may be unmasked after a superior cavopulmonary anastomosis operation, but then “re-masked” after Fontan completion. We describe the complex physiology with an illustrative case report and present a novel method to unmask these pathologic connections after Fontan completion to facilitate transcatheter occlusion and resolve downstream symptoms.
Effectiveness of mHealth for modification of dietary habits and physical activity among individuals at risk or suffering from noncommunicable diseases in primary healthcare settings in South East Asian Region countries – A systematic review and meta-analysis
Authors: Banerjee Bratati , Dutt Debashis , Saha Indranil , Paul Bobby , Lachyan Abhishek Shivanand
Published: January 2023

Background:

Noncommunicable diseases (NCDs) are increasing, for which some behavioral risk factors are major concerns. mHealth has been found to be effective in changing these behavioral patterns.

Objective:

To assess effectiveness of mHealth technology in modification of dietary habits and physical activity, among individuals having NCDs or their risk factors, in primary healthcare settings in South East Asian Region Countries.

Materials and Methods:

A systematic review and meta-analysis was done with the primary outcome as effectiveness of mHealth for improving dietary practices and increasing physical activity. Articles were retrieved from PubMed, Cochrane Central, Google Scholar, and Pre-print servers followed by forward and backward searching. Quality and risk of bias of included studies were assessed. Meta-analysis was performed using RevMan v. 5.4.1 software. Heterogeneity was tested using χ
2 test and measured using I
2 statistic, with Forest plots as the final outcome.

Results:

Nine publications from seven studies, of which seven were conducted in India and two in Bangladesh, qualified for the review. All studies used varied mHealth interventions. Most studies reported beneficial effects in reducing inadequate/improper diet and insufficient/improving physical activity, at community/workplace settings, except two studies reporting no apparent impact, both being from Bangladesh. Meta-analysis revealed statistically significant differences between intervention and control groups for pooled estimates of reduced dietary energy and increased fruits/vegetables. Although heterogeneity is absent between studies considered for fruits/vegetables, both studies were compromised in quality and bias. Studies on dietary energy intake had high statistical heterogeneity, in addition to having high risk of bias. Hence, the results need to be interpreted with caution. No effect was observed on increasing physical activity.

Conclusion:

mHealth interventions have huge potential to facilitate behavior change. However, more research is needed before its potential scale-up.
Increasing The Stocking Density of Grouper Nurseries for Aquabusiness Efficiency in Recirculating Aquaculture System (RAS) with Bioremediation
Authors: Astari Belinda , Budiardi Tatag , Ismi Suko , Effendi Irzal , Hadiroseyani Yani
Published: January 2023

Water quality improvement was carried out by means of recirculation and bioremediation systems in grouper nurseries with high stocking density, thereby increasing production performance. The goal of this study was to evaluate the effectiveness of aquabusiness by analyzing the rise in grouper nursery stocking density using RAS and bioremediation systems. The test parameters consist of production performance, blood glucose levels, physic-chemistry-biology of water quality, and business efficiency based on productivity and business analysis. Treatment of 1,000 fish/m3 increased survival, blood glucose levels, total bacteria, Vibrio spp., ammonia, nitrite, and all productivity parameters. But it lowers all growth parameters, pH, and dissolved oxygen values. The recirculation system with bioremediation at up to 1,000 fish/m3 of stocking boosted the profit by 2.64 times. and 14.97% more efficient than 500 fish/m3 which could not be matched by the high production performance.
Reef Fish Biodiversity at Different Depths in Tunda Island, Banten Province, Indonesia
Authors: Mujiyanto Mujiyanto , Syam Amran Ronny , Suharti Sasanti R. , Sugianti Yayuk , Sharma Saras
Published: January 2023

Reef composition and diversity of coral reef fishes play an essential role in the ecosystem. The reef fish diversity is a crucial indicator of the health level of coral reef ecosystems. The benefit of fish diversity in coral reef ecosystems is to describe ecological services. This research intended to determine reef fish diversity among stations at different depths, consisting of shallow water and reef slope. Research sampling was done in July 2018 and July 2019 in Tunda Island waters at eight stations billowing the coral distribution pattern. Collected data of reef fishes were by using Underwater Visual Census (UVC) on Belt Transects Method at 250 m2 transect area (50 meters of length and 2.5 m on either side). The result showed 69 reef fishes in shallow water and 67 species on the reef slope. The total of fish species ware from 13 families consisting of Acanthuridae, Apogonidae, Blenniidae, Chaetodontidae, Ephippidae, Haemulidae, Labridae, Lutjanidae, Nemipteridae, Pomacentridae, Pseudochromidae, Scaridae and Serranidae. The community services structure of coral reef fishes is included in the moderate community stability category with an H’ value ranging from 1.19-1.60 in shallow water and 1.23-1.44 at reef slope, respectively. Diversity in coral reef fish communities might be associated with species' spatial distribution over the reef habitat's physical structure, but these patterns could be highly scale-dependent. In general, it could be said that the higher the coral reef diversity, the higher the reef fish diversity.
Morphological and Anatomical Comparison between Tetraploid Stevia rebaudiana (Bertoni) Bertoni and its Parental Diploid
Authors: Adabiyah Rifatul , Ratnadewi Diah , Ermayanti Tri Muji , Al Hafiizh Erwin , Susanti Elsa May
Published: January 2023

Stevia rebaudiana (Bertoni) Bertoni is a perennial herbaceous plant that produces natural low glycemic-index sweeteners alternative to sugar cane. The genetic improvement of Stevia needs to be investigated to increase its productivity. Although this plant has a narrow genetic diversity, genetic improvement through polyploidization may succeed. Meanwhile, genotypic characters of tetraploid Stevia were previously reported. This study then observed the phenotypic characters of the tetraploid plants, which aimed to evaluate the morphological and anatomical characteristics of tetraploid Stevia clones compared to its wild-type parental diploid plant. Three tetraploids and one diploid clone were grown in the field for 12 weeks. The results of qualitative descriptive characters showed that the tetraploid clones B60.3H8, P1T22 and P3T5 had habitus type, shoot bud shape, leaf margin, leaf venation, shape, and type of stem, type of flower, and seed similar to the diploid parental clone. However, the quantitative characters showed that the tetraploid clones had leaf size, stem diameter, root size, length of the single flower, length of the flower stalk, and length of fruit which were more extensive than those of the parental diploid clone. The leaf color of tetraploids was a darker green, and the range of initial flowering times was earlier. This finding gives more understanding of the phenotypic and anatomical characteristics of Stevia tetraploids compared to their parental diploid plant.
Implementing Japanese PMA Organizational Culture in Indonesia impacts Employee Job Satisfaction, Employee Performance and Employee Retention of Japanese and Indonesian Employees
Authors: Martadinata Martadinata , Susanti Evi , Anindita Rina
Published: January 2023

The expansion of Japanese parent companies worldwide has forced them to carry the organizational culture that the Japanese founders had held onto their overseas subsidiaries. The main purpose of study is examined organizational culture, employee job satisfaction, and employee performance of Japanese PMA companies in Indonesia on employee retention. Eight Japanese companies were used as the sample, where 33 Japanese employees and 222 Indonesian employees were respondents. Theory Z is used to discuss organizational culture. The questionnaire was made in Indonesian, English, and Japanese. The research model uses a tiered structure model, while to test the proposed hypothesis, the SEM Lisrel 8.8 analysis technique is used. The main finding is the organizational culture of Japanese companies in Indonesia strongly influences job satisfaction, employee performance, and employee retention. Applying Japanese corporate culture shows that Japanese and Indonesian employees understand the company's core values. Employee performance can be realized by employees being able to understand the cultural values of the organization.
Nozzle Flow Separation Phenomena and Control for different conditions
Authors: Mane Shreya
Published: January 2023

A detailed study of separated nozzle flows has been conducted. For a subscale, non-axisymmetric, two-dimensional, convergent divergent nozzle, schlieren flow visualization was acquired along with measurements of force, moment, and pressure as part of an extensive static performance evaluation. Additionally, two-dimensional numerical simulations were performed using the computational fluid dynamics package PAB3D together with algebraic Reynold’s stress modelling and two-equation turbulence closure. This study's experimental findings show that shock-induced boundary layer separation, which was classified into two distinct flow regimes: three-dimensional separation with partial reattachment and entirely detached two-dimensional separation, dominated off design over expanded nozzle flow. The impact of variable shock generation and reflections in various nozzle types on the two primary separation modes, namely Free and Restricted Shock Separation (FSS & RSS), is investigated. The flow separation problem in rocket nozzles has been an unwelcome phenomenon for engineers ever since the birth of the space era. Naturally, the engineers were given the job of bringing things under control. But it proved to be a difficult endeavor; despite the fact that many people were able to explain the physics underlying this occurrence, it is still not completely understood today.
Theoretical Aspects on Heat Transfer and Fluid Flow in Micro Channels
Authors: Mane Shreya
Published: January 2023

The past ten years have seen a lot of research on the issues of heat transfer and fluid flow in micro-channels. With an emphasis on upcoming research requirements, a critical analysis of the state of research as it stands is offered. Following a brief introduction, the study discusses six themes related to transport phenomena in micro-channels: condensation, cooling of electronics, single-phase gas flow, augmentation of single-phase liquid flow and flow boiling, and micro-scale heat exchangers. In this study, we investigate the three-dimensional heat transfer and water flow properties in a set of rectangular micro-channel heat sinks for advanced electronic systems. Over the past ten years, mini/micro channel type compact heat exchangers have received a lot of attention. The ability to make heat exchangers smaller, lighter, and cheaper than those in use now is the primary motivator. Additionally, emerging applications that call for the cooling of small things, such electronics and micro-electro-mechanical devices, need for heat exchangers with tiny channels. Theoretically, it is examined how a nanofluid moves and transfers heat through a horizontal micro channel while being affected by a magnetic field and an electric double layer (EDL). The flow problem for a micro channel with a large aspect ratio is handled as a two-dimensional nonlinear system. The magnetic field and EDL body force are taken into account while calculating momentum equation
Experimental and Computational Investigation of Sounding Solid Rocket Motor
Authors: Jadhav Shruti Dipak , Nag Tapas Kumar , Bandyopadhyay Atri , Pratap Singh Raghvendra
Published: January 2023

Experimental sounding rockets are important contributors to aerospace engineering research. However, experimental-sounding rockets are rarely used for student research projects by institutes in India. The unavailability of rocket motors, which require complex machining and explosive propellants, is a major barrier to the use of sounding rockets in student research projects. We ran into this problem while developing a sounding rocket motor for project and learning purposes. The project focuses on designing and constructing a solid rocket motor that researchers can use as the primary propulsion unit in experimental sounding rockets. Initially, basic designs were evaluated, as various concepts of observations of propellant configuration. The accessibility and ease of use of manufacturing and casting of propellants played a significant role in determining the best propellant based on these findings, the theoretical values for combustion chamber parameters were obtained. Also, materials were chosen accordingly, and a fundamental small-scale experimental design was built and extensively tested. This small-scale motor was created by combining all of the analysis and theoretical data.At experimental testing, we got to know the thrust generated is 763.47N and the motor runs for 4.1 sec, the total mass of the propellant is maxed at 1500g which gives us the max mass flow rate of 0.65Kg/sec this is the output for our solid rocket motor.
Comparative Study on Nose Cones with respect to Angle of Attack using CFD
Authors: Prajapati Sheetal , Mishra Ankit Kumar , Akshay Masetty
Published: January 2023

A nose cone is the conically shaped forward most section of a rocket, guided missile or aircraft, designed to modulate oncoming airflow behaviours and minimize drag. In this paper, the authors analysed by means of a computational procedure the influence of varying the angle of attack for shapes of rocket nose cones in each of them, with this analysed and calculated the values of the, coefficient of lift and the coefficient of drag generated by our nose cones having as a working parameter in subsonic medium ranging from a Mach 0.03 to approximately 0.50, considering standard conditions for temperature and pressure. Drag and Lift both are aerodynamic forces which need to be calculated for cones. Objects with every kind of shapes experience a significant magnitude of Cl and Cd from airflow with the use of the ANSYS platform based on the CFD Fluent method it was possible to measure behaviour in the 3 shapes of cones and thus analyse the different contours. We showed the variation of pressure and velocity with their graphs. The scope of this paper is to simulate the different nose cones with different angle of attack for taking out the best result and comparing which one cone is best for which angle of attack.
Comparative Study on Hybrid Rocket Fuels for Space Launch Vehicles Moving in Higher Orbits
Authors: Bandyopadhyay Atri , Mishra Ankit Kumar
Published: January 2023

The current research is focused on understanding the propulsive parameters of hybrid rocket motors. A comparative study is prepared from various research papers. The fuels paraffin wax, hydroxyl-terminated polybutadiene (HTPB) and polymethyl methacrylate (PMMA) with added additives (Al/Mg) were combined with two oxidizers, liquid oxygen (LOX), nitrous oxide (N2O). The propulsive parameters examined were the combustion efficiency, combustion or adiabatic flame temperature, characteristics velocity and regression rate. The propellant pair paraffin-N2O provided the highest performance for all parameters studied. This study provides an advantageous propellant option for future rocket propulsion based on a comparative investigation
Perinatal Kayıp Sürecinde Babaların Deneyimleri: Sistematik Derleme
Authors: EVGİN Hilal , HOTUN ŞAHİN Nevin
Published: January 2023

Amaç: Kayıp yaşayan bireylerin çevresindeki kişiler ve sağlık çalışanları daha çok annenin yaşadığı fiziksel ve psikolojik duruma odaklanılırken, babaların yaşadığı deneyimler gözden kaçırılmaktadır. Bu sistematik derlemenin amacı yaşanan bu zor süreçte babaların yaşadıkları deneyimlerin neler olduğunun anlaşılmasıdır. Yöntem: Literatür taraması, son on yılda yapılan çalışmaları içeren ‘PubMed, Science Direct, Google Scholar ve Cochrane’ veri tabanları taranarak 2011-2021 yılları arasında konu ile ilgili çalışmalar 1-30 Nisan 2021 tarihlerinde incelendi. Son on yılda yapılan, tam metin elde edilen, İngilizce dilinde yayınlanan ve perinatal süreçte kayıp yaşayan babaların deneyimlerini içeren on altı çalışma dahil edildi. Bulgular: Çalışmalardan elde edilen bulgular PRISMA bildirimi kriterleri esas alınarak analiz edildi. Bu çalışmaların dokuzu nicel, altısı nitel ve biri karışık araştırma tasarımına sahip olduğu bulundu. Konuyla ilgili çalışmaların en çok Avustralya’da olduğu dikkat çekerken ülkemizde bu alanda yapılmış çalışmaya rastlanmamıştır. Sonuç: Babaların yoğun bir şekilde yas duygusu deneyimlediği, en çok desteği eşlerinden aldıklarını ancak yine de yetersiz destek gördükleri saptanmıştır. Profesyonel destek almak istedikleri, daha çok rasyonel başa çıkma mekanizmaları kullandıkları, erken gebelik döneminde babalık rolünün oluştuğu ve eşlerini destekleyici rolü üstlendikleri belirlenmiştir. Toplum genelinde farkındalık oluşturarak babaların bu süreci daha kolaylıkla atlatmalarına yardımcı olunmalıdır.
The Somatosensory Perceptions of Individuals Living in Istanbul During The Covid-19 Pandemic Process
Authors: KENDİRKIRAN Gülcan , USLU Esra
Published: January 2023

Aim: This study was planned to evaluate individuals’ somatosensory perceptions during the pandemic process. Subject and Method: The study used a descriptive and cross-sectional design and was carried out with the participation of 613 individuals who were aged between 18 and 65 and lived in Istanbul. Data were collected using a Personal Information Form and the Somatosensory Amplification Scale (SSAS). Mann-Whitney U test, Kruskal-Wallis H test, and Bonferroni correction were used for data analysis. Results: According to the findings, 69.3% of the participants were female, 53% had an undergraduate degree, and 12.4% had chronic diseases. The SSAS scores were statistically significantly higher in those who were female (Z=-6.028, p=0.000), had a chronic disease (Z=-2.760; p=0.006), were afraid that they/their family members would get infected with COVID-19 (Z=-4.220; p=0.000), had tested positive for COVID-19 (Z=-2.305; p=0.021), and had a relative who tested positive for COVID-19 (Z=-2.549; p=0.011) (p
YENİDOĞAN ÜNİTELERİNDE ÇALIŞAN HEMŞİRELERİN YENİDOĞAN CİLT BAKIMINA YÖNELİK BİLGİ DÜZEYLERİNİN BELİRLENMESİ
Authors: TEKDAL Sibel , KOKCU DOGAN Aysel
Published: January 2023

Amaç: Yenidoğan ünitelerinde çalışan hemşirelerin yenidoğan cilt bakımına ilişkin bilgi düzeylerini incelemektir. Örneklem ve Yöntem: Tanımlayıcı bir çalışma olan araştırmanın örneklemini, İstanbul’da bulunan bir devlet ve bir vakıf üniversitesi hastanesinin yenidoğan ünitelerinde çalışan ve araştırmaya katılmaya gönüllü 162 hemşire oluşturmuştur. Verilerin toplanmasında “Tanıtıcı Bilgiler Formu” ile “Yenidoğan Ünitelerinde Çalışan Hemşirelerin Yenidoğan Cilt Bakımına Yönelik Bilgi Düzeylerinin Belirlenmesi Formu” kullanılmıştır. Araştırmadan elde edilen veriler SPSS 22.0 paket programında analiz edilmiştir. Bulgular: Hemşirelerin %92’sinin kadın, %60.5’inin lisans mezunu olduğu, %74.1’inin devlet hastanesinde çalıştığı ve %32.7’sinin yenidoğan yoğun bakım hemşireliği sertifikasının olduğu belirlenmiştir. Hemşirelerin; yenidoğan cilt bakımına yönelik puan ortalamaları 80.93 ± 12.96’dır. Hemşirelerin yaş ortalaması, eğitim düzeyi, çalıştığı kurum, meslekteki çalışma yılı, yenidoğan yoğun bakımlardaki çalışma süreleri ve yenidoğan sertifika programlarına katılma durumları ile bakıma ilişkin bilgi düzeyleri arasında pozitif yönlü anlamlı bir ilişki (p<0.05) saptanmıştır. Sonuç: Araştırmaya katılan hemşirelerin yenidoğan cilt bakımına ilişkin bilgi düzeylerinin ortalamanın üstünde olduğu saptanmıştır. Bu sonuçlar ışığında, yenidoğan cilt bakım uygulamalarının tüm sağlık kurumlarında standart hale getirilmesi, deneyimli ve uzman hemşirelerin bu alanda çalıştırılması, hemşirelerin yoğun bakım sertifika programlarına katılımının sağlanması gerekmektedir.
Evaluation of Nutritional Status, Physical Performance, and Sarcopenia in Older Adults: Example of Antalya 60+ Tazelenme University
Authors: KAMARLI ALTUN Hülya , GUNES GENCER Gokce Yagmur , SUNA Gülen , ŞEN Büşra , YILMAZ Gözde
Published: January 2023

Aim: This study aims to evaluate the nutritional status, physical performance, and sarcopenia status of 60+ Tazelenme University students. Subject and Method: This cross-sectional study included 214 older adults who attended the 60+ Tazelenme University between January and May 2020. The subjects were questioned about their dietary habits, anthropometric measurements were taken, and a Mediterranean diet adherence scale and 24-hour dietary recall were used to evaluate their nutritional status. The physical activity scale for the elderly, the 5 times sit to stand test, and time up to go test were applied in assessing their physical performance. Results: The mean age of the subjects was 66.4±4.4 years, and most of them were women (71.0%). It was found that 38% of the daily energy intake came from carbohydrates and 44.5% from fats, and one out of every four older adults had a low score for adherence to the Mediterranean diet. Only 3.7% of the older individuals were sarcopenic. A weak positive correlation (r=0.143, p=0.037) was found between the physical activity scale for the elderly and Mediterranean diet adherence scale scores. Also, there was a moderately positive correlation between fat-free mass and handgrip strength (r=0.615, p=0.001) and a weak negative correlation between walking speed (r=-0.139, p=0.043) and time up to go test (r=-0.195, p=0.003). Conclusion: It is thought that this study will contribute to the literature in the development of adequate and balanced nutrition and physical activity education models for older people by providing information about the nutritional profiles and physical performance of those studying at Tazelenme University.
Profit and Loss Report of DSH Meat Stalls in Panumbangan Market
Authors: Zahra Ami Emilia Putri , Subartini Betty
Published: January 2023

DSH Meat Kiosk is a kiosk that sells one of the foodstuffs, namely Beef. This DSH Meat Stall has been established for more than 20 years. However, as long as the kiosk has been standing, the manager still finds it challenging to analyze profits from sales. Therefore, the Preparation of a Profit - Loss Financial Report is intended to assist traders in managing the profits generated. This report makes a financial analysis of November 2021 and February 2022. The method used in preparing this report is using primary data by collecting data in the form of interviews with kiosk owners regarding matters needed in preparing profit and loss reports such as assets held and owned, total income, operational costs and others. The results of this report show that sales in February 2022 decreased by 17.88% compared to November 2021. It is hoped that this report will help and make it easier to manage the profit generated and make decisions to make the best profit.
Psychometric properties of the Turkish version of the COVID-19 Impact Scale in university students
Authors: Yıldırım Murat , Şanlı Mehmet Emin
Published: January 2023

The psychological impacts of the COVID-19 pandemic have substantially changed and this requires a new measurement tool reflecting these changes. The COVID-19 Impact Scale (CIS) assesses the psychological stress responses to the COVID-19 pandemic. This study, for the first time, examined the psychometric properties of the Turkish version of the CIS in university students by focusing on its internal consistency reliability, factor structure, criterion validity and predictive validity. Using a cross-sectional research design, data were collected from 486 university students studying at a public university in Turkey. Participants completed the CIS and Kessler Psychological Distress Scale-6 using an online survey. The results showed that the CIS had excellent internal consistency reliability. Results of exploratory and confirmatory yielded a one-factor solution for the scale with high factor loadings. Also, the results showed that the CIS was not only significantly positively correlated with psychological distress but also accounted for a significant amount of unique variance in the prediction of psychological distress after controlling for the effects of age and gender. These results suggest that the CIS is a psychometrically sound scale with good evidence of reliability and validity in Turkish university students. The CIS can be confidently used for research and clinical practices.
Microbes Knocking Louder Roles for Next Green Revolution: A Meta-Analysis
Authors:   Regional Agricultural Research Station- Titabar, Assam Agricultural University, Jorhat, Assam, India, BORA POPY
Published: January 2023

Feeding the ever-growing population has always been a daunting challenge to researchers, however on the contrary, itopened the floodgate of innovative technologies, especially of late, with the introduction of meta-genomics unfolding those genetic traits of microbes, which otherwise remained unexplored for a very long time.Learning negative consequences of previous green revolution in terms of various chronic environmental issues, phyto-microbiome analysis(microbiome bioprospecting)leading to identification of many plant growth promoting microbes, disease suppressive antagonists including entomopathogenic microbes and agrochemicals residues cleansing microbes,preferably in a bioformulation mode have evoked a very strong claim to be stitched into modern day agriculture, claimed close to chemical residue free organic as well as natural agriculture, a pre-requisite to stake claim for next green revolution. Such microbial interventions are likely to ensure three major paradigm shifts in agriculture viz., i. over-use of pesticides to residue free precision farming, ii. traditional to intelligent farming and iii.input-intensive (high cost of production) to climate- smart solutions, all collectively look forward towardsmore sustainable development of agriculture. All these issues have been systematically analysed through bibliometric evidences and envisioned the future course of action to realise yet another green revolution through microbial interventions.
Entrepreneurship to Private Limited Company: SLN Coffee Pvt. Ltd. Co's Success Story on Creating a Successful Brand Levista
Authors: V. A. Namreen Asif , Panakaje Niyaz
Published: January 2023

Background/purpose: The context in which entrepreneurship in the cultural and creative industries (CCI) occurs was the focus of this study. Entrepreneur inspiration is a type of motivation that allows creative ideas to be transformed into creative products. The company SLN Coffee Pvt. Ltd. Co., which started with the acquisition of a coffee plantation and later entered the trade of green coffee beans before becoming a brand coffee business in 2004, has experienced rapid and steady growth. This success can be attributed to a variety of factors worth discussing.
Objective: To examine the development of SLN Coffee Pvt. Ltd. Co. and the factors that contributed to this growth into a brand.
Design/Methodology/Approach: Information gathered from primary and secondary data is analyzed and presented. utilizing the SWOC framework, numerous scholarly articles, web articles, company websites, and interviewing techniques.
Findings/result: It has been found, findings of a study conducted using a variety of resources and the analysis of data, that competing in a market is a challenging endeavour that calls for the application of multiple methods and processes. creativity and innovation.
Research limitations/implications: The evaluation and solutions presented in this paper are only applicable to industries with a limited to similar business model, yearly revenue, and level of expertise to SLN Coffee Pvt. Ltd. Co.
Originality/value: This paper focuses on the various factors and scenarios that have enabled the SLN Coffee Pvt. Ltd. Co to grow and be labelled as a brand in the coffee industry.
Paper type: A Research Case study paper on journey of SLN Coffee Pvt. Ltd. Co in becoming the successful coffee Brand in comprehensive coverage of the coffee Industry.
Arundhati Roy as an Environmentalist with Special Reference to the Context of Covid-19
Authors: Ranjith Reena , K. T. Manjula
Published: January 2023

Purpose: This paper examines the environmental concerns of Arundhati Roy as expressed in her fictional writings, assessing the impact of her thoughts and views on the human endeavour to curb environmental hazards.
Methodology: The primary sources of information are the texts’ The God of Small Things and The Ministry of Utmost Happiness’. The secondary sources, scholarly articles in journals are taken from internet resources. Qualitative research is done based on the available literature.
Findings: This study attempts to show that environmental issues need a lot of attention in order to gradually tackle the main problems and the effects of COVID-19 on the environment and society. Roy is of the opinion that everyone in the world ought to have access to basic necessities including food, housing, and medical care.
Originality: This paper analyses how Arundhati Roy has played a significant role in being an environmentalist, analysing the issues in the environment and trying to find solutions for them.
Paper Type: Analytical Research Paper.
Territorial males have larger wing spots than non-territorial males in the damselfly Calopteryx splendens (Zygoptera: Calopterygidae)
Authors: Kaunisto Kari M. , Suhonen Jukka
Published: January 2023

Males of Calopteryx splendens use two alternative mating tactics, territoriality, and non-territoriality. These different mating tactics are shown to vary between males within the same population and previous studies have shown that territorial males have considerably higher fitness than non-territorial males. In this paper, we tested whether the wing spot size as sexual ornament, wing length, relative wing spot size, asymmetry in wing length, asymmetry in wing spot size, or asymmetry in relative wing spot size differed between the territorial and non-territorial males. We sampled C. splendens males, representing both mating tactics, from a river system in south-west Finland. According to our results, territorial males have larger wing spot than non-territorial males. In contrast, there were no differences in the other tested traits between the territorial and non-territorial males. In conclusion, our data show that the size of pigmented wing spots may predict the alternative mating tactic of C. splendens males.
Mixed Connective Tissue Disorder: A Rare Case Report
Authors:   Department of General Medicine, Basaveshwara Medical College and Hospital, Chitradurga, Karnataka, India, Sunil Pattanshetty , Swathi Hadagali , Kauser Murtuza , Marulasreshta G D , Kumar S R Vagesh , Prashanth G
Published: January 2023

MCTD is a rare disease with overlapping features of many connective tissue disorder and the presence of positive anti-U1RNP antibodies with anti-ssA (Ro), anti-ssB (La) being negative. We report a case with fever and edema of upper limb and lower limb small joints associated with violaceous discolouration which on further evaluation led to diagnosis of MCTD. A female aged 44 years presented with history of fever of moderate degree with no diurnal variation and subsides on taking medication for 7 days and had also noticed ecchymoses followed by maculopapular rashes (violaceous) associated with tenderness of fingers and toes (more on exposure to cold). On further evaluation led to a diagnosis of MCTD. This case report urges the clinicians to exercise great caution for connective tissue diseases in patient presenting with similar history. This rare case of disease is uncommon in the available literature, especially for this ethnicity or region. This report should be of great interests to all diagnosticians of internal medicine. Keywords: Mixed connective tissue disorder, Raynaud’s phenomenon, sclerodactyly, Anti-U1nRNP antibody, Scleroderma