bluuebunny/crossref_metadata_2025 huggingface dataset:
Open Reduction and Internal Fixation of Acute Lisfranc Fracture-Dislocation with Use of Dorsal Bridging Plates
Authors: Stødle Are Haukåen , Nilsen Fredrik , Molund Marius , Ellingsen Husebye Elisabeth , Hvaal Kjetil
Published: November 2019

Lisfranc injuries consist of a wide spectrum of injuries, ranging from subtle injuries to severe fracture-dislocations. Injuries with instability of the tarsometatarsal, intercuneiform, or naviculocuneiform joints should be treated with anatomic reduction and stable fixation. The best method of fixation is debated. Transarticular screw fixation has the disadvantage of damaging the tarsometatarsal joints. Bridging the tarsometatarsal joints with use of low-profile locking plates avoids the placement of screws through the joint and potentially reduces the risk of posttraumatic arthritis. Primary arthrodesis of the 3 medial tarsometatarsal joints is also an option in treating Lisfranc injuries and has been shown to lead to better outcomes compared with transarticular screw fixation in ligamentous Lisfranc injuries. In this article, we show the technique of open reduction and internal fixation of Lisfranc fracture-dislocation with use of dorsal bridging locking plates. The following steps are presented in the video: (1) incision technique with use of a dorsomedial incision and a dorsolateral incision, (2) open reduction and temporary fixation of the tarsometatarsal joints with use of Kirschner wires, (3) confirmation of anatomic reduction of the tarsometatarsal joints with direct visualization and fluoroscopy, (4) fixation of the medial 3 tarsometatarsal joints with dorsal bridging locking plates, (5) placement of a “homerun” screw from the medial cuneiform to the base of the second metatarsal, (6) fixation of the fourth and fifth tarsometatarsal joints with Kirschner wires, and (7) checking of reduction and fixation with use of fluoroscopy and performance of wound closure. Postoperatively, the foot is kept non-weight-bearing in a below-the-knee cast for 6 weeks, followed by 6 weeks of protected weight-bearing in a walker boot. Any Kirschner wires fixating the fourth and fifth tarsometatarsal joints are removed 6 weeks postoperatively. We prefer to remove the dorsal bridging plates 4 to 6 months postoperatively. Anatomic reduction and stable fixation is associated with better functional outcomes. Hardware failure and loss of reduction are potential complications that can lead to worse outcomes.
Isolation and Characterization of Potential Isolates of Rhizosphere Bacteria to Contro Budok Disease in Patchouli Plant
Authors: Sukamto NFN , Listiana Novi , Indrayanti Reni , Wahyuno Dono
Published: November 2019

Synchytrium pogostemonis, the causal agent of budok disease, is one of the major limiting factors in patchouli production in Indonesia. Patchouli farmers usually control budok disease with chemical fungicides. Chemical control pollutes environment and disrupts agricultural ecosystem. Therefore, an environmentally friendly pest control should be conducted to control the disease. The objective of the study was to isolate and evaluate some rhizobacteria from the rhizosphere of patchouli and black pepper plants against Fusarium oxysporum f.sp. vanillae, F. solani, Sclerotium rolfsii. Potential rhizobacterial isolates were tested to control budok disease on a pot scale. The results showed that 26 rhizobacterial isolates from 100 tested were antagonistic to F. oxysporum, F. solani and S. rolfsii. Four rhizobacteria isolates (RL13-A, RL31-A, RL35-A, RL32-A) showed strong inhibition (>40 %) against the 3 pathogens. In polibag experiment, RL35-A, PS9, RL13-A, RL32-B, RL31-A isolates were able to suppress budok disease significantly by 84.01; 76.00; 65.99; 43.99; and 21.98 % respectively. These results indicated that RL35-A isolates have strong antagonistic effect compared to other isolates. Based on 16S rDNA analysis, RL35-A isolates possessed close relationship (99 %) with all species of Enterobacter sp. The antibiotic compound extracted from RL35-A culture broth using GC-MS analysis was identified as phenol, 2,6-dimethoxy-(canola). These results suggested that Enterobacter sp. was potential to be developed as biological agent for controlling budok disease in patchouli plants.
Aligning the Stars: Understanding Digital Scholarship Needs to Support the Evolving Nature of Academic Research
Authors: Hurrell Christie
Published: November 2019

Digital scholarship centres located within academic libraries are proliferating. This project gathered feedback from library staff and researchers at the University of Calgary to inform the development of a physical space and associated services to support the evolving nature of academic research. Semi-structured interviews were conducted, and the results were analyzed thematically. Common needs identified included access to interdisciplinary collaborators, technologies, and space. The library was beginning to renovate an existing space to support collaboration and, informed by this research, reconfigured and realigned services and expertise to support digital scholarship in a more cohesive manner. This study will be of interest to other academic libraries wishing to develop a digital scholarship centre that is responsive to the needs of their local community.
Nuclear-Magnetic-Resonance Monitoring of Mass Exchange in a Low-Permeability Matrix/Fracture Model During CO2 Cyclic Injection: A Mechanistic Study
Authors: Wei Bing , Gao Ke , Song Tao , Zhang Xiang , Pu Wanfen , Xu Xingguang , Wood Colin
Published: November 2019

Recent reports have demonstrated that carbon dioxide (CO2) injection can further raise the oil recovery of fractured tight reservoirs after natural depletion, with major projects in progress worldwide. There is, however, a lack of understanding of the mass-exchange process between the matrix and fracture at pore scale. In this study, a matrix (0.8 md)/fracture model was designed to experimentally simulate a CO2-cyclic-injection process at 80°C and 35 MPa (Lucaogou tight formation). The oil (dead-oil) concentration in the matrix and fracture was continuously monitored online using a low-field nuclear-magnetic-resonance (NMR) technique aiming to quantify the oil recovery in situ and clarify the mass-exchange behaviors. The results showed that CO2 cyclic injection was promising in improving the oil recovery of fractured tight reservoirs. Nevertheless, the oil-recovery rates rapidly declined with the cycle of CO2 injection and the incremental oil was primarily produced by large pores with 100 ms > T2 > 3.0 ms. The NMR T2 profiles of the model evidenced the drainage of the matrix oil by CO2 toward the fracture. Because of the light-hydrocarbon extraction, the produced oils became lighter than the original oil. We noted that the main driving forces of the incremental oil recovery were CO2 displacement, CO2/oil interactions (mainly extraction and solubility), and pressure gradient (depressurization). In the first cycle, the CO2/oil interactions driven by CO2 diffusion during soaking enhanced the mass exchange between the matrix and the fracture. However, from the second cycle, CO2/oil interactions and CO2 displacement became insignificant. The results of this study supplement earlier findings and can provide insights into the CO2-enhanced-oil- recovery (EOR) mechanisms in fractured tight reservoirs.

NOTE: Supporting information available.
Prolonged haemodialysis increases the risk of the impairment of global longitudinal strain in patient after kidney transplantation and a preserved ejection fraction of left ventricle
Authors: Obremska Marta , Goździk Anna , Szymczak Maciej , Zysko Dorota , Boratyńska Maria , Letachowicz Krzysztof , Madziarski Marcin , Krajewska Magdalena
Published: November 2019

Background. Patients with chronic kidney disease, including these after kidney transplantation (KTx), have higher cardiovascular mortality. Global longitudinal strain (GLS) detects subtle changes in the left ventricle (LV) and is more sensitive predictor of cardiovascular mortality than the LV ejection fraction (LVEF).The aim of this study was to assess the prevalence of impaired GLS among kidney transplant recipients with preserved LVEF. We also aimed to identify possible clinical factors responsible for GLS impairment. Methods. A total of 79 patients following KTx with preserved LVEF and no history of cardiac disease were evaluated. We assessed echocardiogram parameters with the calculation of GLS, laboratory parameters, presence of diabetes, hypertension, duration of haemodialysis (HD) and time after KTx. An impaired GLS value was set on ≥-18%. The multivariate stepwise logistic regression analysis were used to identify the factors related to impaired GLS. Results. Among 79 (42 females, mean age 60.3) kidney transplant recipients with preserved LVEF, 39% had impaired GLS. ROC analysis revealed that the cut-off point for the prediction GLS ≥-18 % by HD duration is more than 28 months (AUC 0.67 (95%CI 0.545-0.79; P=0.007). In multivariate stepwise logistic regression analysis for variables related to impaired GLS duration of HD more than 28month is associated with GLS ≥-18( OR 4.06; 95CI (1.45-11.34) P=0.008). Conclusions. In our study group, a total of 39% of KTx patients with preserved LVEF had impaired GLS. The risk factor of GLS impairment was a prolonged duration of HD (>28months) prior to the transplantation procedure.
Molecular-based survey of Rickettsia spp. and Coxiella burnetii in mosquitoes (Diptera: Culicidae) from Fars province, southern Iran, during 2017-18
Authors: Hoseini Zahra , Alipour Hamzeh , Azizi Kourosh , Soltani Aboozar
Published: November 2019

Background Mosquito-borne diseases are main problems of public health worldwide, especially in tropical and subtropical regions. Mosquitoes can transmit human filariasis, arboviruses, malaria, and dirofilariasis. It has been recently found that Anopheles gambiae is a vector of Rickettsia felis. Both cells of Anopheles gambiae and Aedes albopictus help developing of R. felis. These studies indicated that mosquitoes could be vector of Rickettsia spp., especially R. Felis. Since there was no study on roles of the Iranian mosquitoes in transmission of Rickettsia spp. and Coxiella burnetii, the present study for the first time investigated roles of mosquitoes in the transmission of these pathogens using the PCR technique in Iran.Methods The present study was conducted in Fars province, and mosquitoes were manually caught (hand-catch, total catch etc.) in Qir and Karzin Counties from four different geographical regions during the activity seasons of mosquitoes in 2017-18. The primers design were done to investigate the probability of mosquito’s contamination with Rickettsia spp. and Coxiella burnetii from gltA genes (Rickettsia sp. citrate synthase kinase) for Rickettsia spp. and IS111 A Transposase gene for Coxiella burnetii. The conventional PCR was used after the extraction of DNA from mosquitoes to study the contamination.Results A total of 1103 adult mosquitoes were collected and identified from four regions of the County. Among them, 3 genera and 11 species were identified including Anopheles (25.74%) (An. dthali, An. stephensi, An. superpictus), Culex (51.84%) (Cx pipiens, Cx sinaiticus, Cx bitaeniorhynchus, Cx theilers, Cx laticinctus, Cx tritaeniorhynchus, and Cx torrentium) and Culiseta (22.39%) (Cu. longiareolata) genera. All tested mosquitoes were negative in terms of contamination to Rickettsia spp. and Coxiella burnetii.Conclusions Based on the results, mosquitoes in this part of the country are not considered as vectors of Rickettsia spp. and Coxiella burnetii currently. In general, limited studies have been conducted on Rickettsial diseases in Iran and since Rickettsia spp. has been reported from different vectors in Iran and other neighboring countries, there is a need for further studies on this field in tropical areas of Iran especially in mosquitoes as a possible vector with high abundance and mobility.
Comparing the Treatment Outcomes of Tuberculosis Patients in Private Clinic with Governmental Health Centre in Jimma City, Ethiopia.
Authors: Abera Eyob Girma
Published: November 2019

Background : Tuberculosis is a common and often deadly infectious disease caused by various strains of mycobacterium, usually mycobacterium tuberculosis in humans. Tuberculosis has long been major cause of morbidity and mortality particularly where the diagnostic and control program is not far extended. Objective : - To compare the treatment outcomes and to describe the social demographic factors associated with Tuberculosis patient in private clinic with governmental health centre in Jimma city, Ethiopia from September 12, 2007 to September 10, 2017. Methods and Materials : - A ten years retrospective systemic record review was conducted to compare the treatment outcomes and to describe the social demographic factors associated with Tuberculosis patient in private clinic with governmental health centre in Jimma city, Ethiopia from September 12, 2007 to September 10, 2017. Data was collected by using questionnaire formats. Since all serial numbers of the patients were used no sampling technique was needed. Finally data was analyzed by SPSS/EPI INFO. Result : The present study revealed that within ten years duration private clinic gives anti-TB treatment coverage for 582 patients whereas governmental clinic gives for 510 patients. The treatment success rate of the private clinic is 98.1% which is 1.03 fold than the governmental health center (95.3%). Governmental health center defaulting rate was triple fold of the private clinic 4.1% and 1.2% receptively, while the treatment failure of private clinic was 0.2%, but no treatment failure in governmental health center. Conclusion and Recommendation -Age, educational level and the types of TB diagnosis and treatment outcome of the patients were statistically associated in both sectors. Better counseling and awareness about the disease should have to be given for every anti-TB treatment receiving patients despite of their educational level and occupational status in both sectors. Keywords: Tuberculosis, Treatment outcome, Comparing, Governmental health center, Private clinic
Association of Serum Ferritin Concentration and Lung Function in the Tobacco-naïve Population: Retrospective population-based study of KNHANES V
Authors: Kim Taeyun , Choi Hyunji , Kang Jihun
Published: November 2019

Background: Ferritin regulates iron homeostasis, and is involved in the inflammation in the lung, especially in smokers; however, its effects on pulmonary function in non-smokers remain unclear. The present study aimed to evaluate the association between serum ferritin and lung function in a tobacco-naïve population.
Methods: In this study, 25,534 individuals were enrolled, among who 5,338 tobacco-naïve individuals were identified; of those, 342 men and 2,879 women (742 pre- and 2,137 post-menopausal) with data of serum ferritin, lung function, and covariates were included. To evaluate the association of ferritin and lung function, multivariable-adjusted linear regression analyses was used including the factors of predicted value of forced expiratory volume in 1 second (FEV 1 %) and forced vital capacity (FVC%) . Logistic regression analyses were used to measure the relationship between ferritin and restrictive and obstructive lung disease.
Results: In pre-menopausal women, FEV 1 %/FVC was weakly but positively associated with serum ferritin, and after adjusting for covariates, the association was without statistical significance. No significant association between ferritin and obstructive lung disease was observed. In post-menopausal women, predicted FVC% was negatively associated with serum ferritin, and ferritin was dose-dependently related with risk for restrictive lung disease. The odds ratio for restrictive lung disease in post-menopausal women was 2.285 at Q3 and 1.560 at Q2 relative to that at Q1.
Conclusions: High serum ferritin level was significantly associated with lower FVC% and increased risk of restrictive lung disease in tobacco-naïve post-menopausal women. Further study is needed to determine the mechanism underlying the current findings.
Study design of a prospective, open-label study comparing increased infusion parameters of a 20% subcutaneous immunoglobulin (IgPro20) in patients with primary immunodeficiency
Authors: Rojavin Mikhail , Hofmann Jutta , Praus Michaela
Published: November 2019

Background: Immunoglobulin G (IgG) replacement therapy can be administered subcutaneously (SCIG) using an infusion pump or by manual push. Both methods have shown similar serum IgG trough levels for the same total weekly/monthly dose as well as safety and tolerability profiles. The currently approved infusion parameters for the SCIG Hizentra® (IgPro20, CSL Behring, King of Prussia, PA, USA) in primary immunodeficiency (PID) in the United States are volumes of ≤25 mL and flow rates of ≤25 mL/h per injection site. Previously, clinical studies and case reports had demonstrated use of higher infusion parameters than those approved, but safety and tolerability of these have not been systematically evaluated. In the absence of regulatory guidance, we have developed a novel prospective clinical study applying forced upward titration design to evaluate the safety and tolerability of high infusion parameters of IgPro20 in PID patients using pump-assisted and manual push techniques (NCT03033745). Results: A total of 45 patients were planned for inclusion. Primary endpoints were defined as the proportion of patients successfully infusing certain infusion parameters (responder rate). The study included three cohorts (n=15 planned per group): 1) Pump-assisted Volume Cohort with weekly infusions at volumes of 25, 40 and 50 mL per injection site; 2) Pump-assisted Flow Rate Cohort with weekly infusions at flow rates of 25, 50, 75 and 100 mL/h per injection site, and 3) Manual Push Flow Rate Cohort with 2 to 7 infusions at flow rates 30, 60 and 120 mL/h per injection site. Each infusion parameter level was tested for 4 weeks, after which those who successfully infused at the current level (responders) were switched to the next level. Responder rate, safety and tolerability were assessed. Study results will be available in early 2020. Conclusions: This study applied a novel and rigorous prospective evaluation of individual safety and tolerability levels of pump-assisted and manual push SCIG at higher infusion parameters than currently approved in the United States and demonstrated their safety and tolerability.
Analysis of transcriptomic changes in bovine endometrial stromal cells treated with lipopolysaccharide
Authors: Ding Xuefen , Lv Haimiao , Deng Lixin , Hu Wenju , Peng Zhan , Yan Chenbo , Yang Dexin , Tong Chao , wang Xinzhuang
Published: November 2019

Background: Endometritis adversely affects the ability of cattle to reproduce, and significantly reduces milk production. Consequently, it has great influence on the economic value of dairy cows. The endometrium is mainly composed of epithelial and stromal cells and they produce the first immune response to invading pathogens. Epithelial cells are the first cellular barrier through which bacteria enter the uterine endometrium. However, most of the epithelial cells are disrupted and stromal cells are exposed to an inflammatory environment when endometritis occurs, especially postpartum. Inflammation in endometrial stromal cells is thus activated, immune-related cytokines and signaling pathways are activated. This indicates that endometritis is becoming more and more serious. However, inflammatory response in bovine endometrial stromal cells is yet to be studied in detail. Understanding the genome-wide characterization of the bovine endometritis will be beneficial for prevention and treatment of endometritis. In this study, whole-transcriptomic gene changes in bovine stromal cells treated with LPS were compared with those treated with PBS (control group) and were analyzed by RNA sequencing (RNA-seq).
Results: Compared with the control group, a total of 366 differentially expressed genes (DEGs) were identified in LPS-induced group (234 upregulated and 132 downregulated genes), with an adjusted P -value＜0.05 by DESeq. Gene ontology (GO) enrichment analysis revealed DEGs were most enriched in lymphocyte activation, interleukin-1 receptor binding, regulation of cell activation, and lymphocyte-activated interleukin-12 production. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed DEGs were most enriched in TNF signaling pathway, Toll-like receptor signaling pathway, cytokine-cytokine receptor interaction, nucleotide-binding oligomerization domain-like (NOD-like) receptor signaling pathway, NF-κB signaling pathway, and chemokine signaling pathway.
Conclusion: Our results proved and expanded findings of previous studies on bovine endometritis. These results will be useful to propose new therapeutic targets and eliminate or reduce inflammation by comprehending molecular mechanisms and authenticating unique genes related to endometritis.
Diagnosis of Viral Myocarditis in Children with Clinical Suspicion of Myocarditis by Multiplex Real-time PCR in Birjand Vali-Asr Hospital, East of Iran
Authors: Salehi Forod , Salehi Shiva , Yousefi Masoud
Published: November 2019

Background Viral myocarditis (VMC) is one of the common heart diseases to endanger human health in different age groups, especially children. The aim of this study was diagnosis of viral myocarditis in children with clinical suspicion of myocarditis by multiplex Real-time PCR in Birjand Vali-Asr hospital.Methods This cross-sectional research conducted on 19 patients with clinical suspicion of myocarditis who had evidence of microbial infections in recent weeks. Routine electrocardiogram and dynamic ECG examinations, auxiliary laboratory testing and echocardiographic evaluation were performed. Multiplex Real-time PCR by Neuro kit was used for detection of viral agents in blood or pericardial fluid samples.Results The results indicated that 4 out of 19 (21.05%) patients with myocarditis were found to be virus positive. The spectrum of viral agents was included HHV-6/7, Parvovirus B-19, EBV, VZV and Adenoviruses. A co-infection of HHV-6/7 and Parvovirus B-19 was found in the one patient. ECG findings such as sinus tachycardia with ST-T changes, premature ventricular contraction and complete heart block were found in VMC patients. The predominant echocardiographic features in the patients with VMC were a low ejection fraction, mitral regurgitation and severe pericardial effusion with hypotension. AST and LDH abnormal increase were found in the some patient.Conclusions Our findings highlight the importance of identification of VMC in children with clinical suspicion of myocarditis. The present study emphasizes the importance of PCR-based assays for detection of viral agents in myocarditis patients with symptoms of virus infection.
Paramedics's perspectives on hospital transfers of nursing home residents - a qualitative focus group study
Authors: Pulst Alexandra , Fassmer Alexander Maximilian , Hoffmann Falk , Schmiemann Guido
Published: November 2019

Background: Emergency department (ED) visits and hospital admissions are common among nursing home residents (NHRs). These transfers are often considered avoidable and can have negative effects on residents’ health status. Emergency medical services (EMS) are an important linking profession between nursing homes (NHs) and hospitals and responsible for transports. So far, little is known about the perspectives of paramedics in this context. The aim of this qualitative study is to explore how paramedics experience hospital transfer process of NHRs and how hospitalizations could be avoided from their point of view.
Methods: A qualitative study with three focus groups was conducted with paramedics. The focus groups followed a semi-structured question guide focusing on issues during transfer process, avoidable hospital transfers and potential interventions which might reduce transfers from NHs. Discussions were audio recorded and transcribed verbatim. Data were analyzed by content analysis using the software MAXQDA.
Results: In total, 18 paramedics (mean age: 33 years, male n=14) participated in the focus groups. Paramedics mainly reported about perceived structural reasons (e.g. understaffing or lack of time) in NHs which led to initiation of an emergency call. Paramedics were often faced with poorly organized handovers because of lacking or incomplete information. In many cases, nursing staff was perceived as insufficiently qualified and not well-prepared regarding health status of NHRs. Throughout transfer process, the behavior of all involved professional groups (dispatcher/ambulance control center, nurses, physicians and paramedics) was influenced by legal uncertainties. Paramedics rated hospital transfers as avoidable in case of urinary catheter complications, exsiccosis/infections and partially in case of falls. Emergency standards in NHs, trainings for nursing staff, improvement of working conditions and legal conditions were discussed as potential interventions which could reduce hospital transfers of NHRs.
Conclusion: Paramedics are faced with complex issues when transporting a NHR to hospital. According to their point of view staff shortage and legal uncertainties play a relevant role in transfer decisions. Interventions reducing (avoidable) hospital transfers of NHRs have to take these factors into account.
Keywords: nursing home residents, hospitalization, hospital admission, patient transfer, referral, transition, emergency department, emergency medical services, decision making, advance care planning
Distinctive Features Analysis of Foreign Language Borrowing Words in Javanese Language Found in Panjebar Semangat Magazine
Authors: Aprillianti Linda
Published: November 2019

The Javanese language belongs to language which has unique phonological system. There are so many foreign language has influenced the development of Javanese. This study is intended to examine the sound change of borrowing word of foreign language in Javanese which is found in Panjebar Semangat magazine. The data is taken from Panjebar and checked using old Javanese dictionary. This study belongs to descriptive qualitative research and used Simak method and Non Participant Observation in collecting the data. The data analysis is done by using Padan method. The result of the study reveals three sound changes of vowels sound and four phonological rules. Then, there are four types of sound change and four phonological rule of consonant sound. The result showed that the sound change of borrowing word in Javanese is influenced by the differences of phonological system between Javanese and the foreign language.
From Abstract to Concrete: Associating the Users’ Tweets on “Success”
Authors: Fitria Fitria , Tur Ajar Pradika Ananta
Published: November 2019

By having Twitter for their interaction, users are demanded to express their idea in short-clear-easy to understand tweets. This condition pushes them to formulate every single word to conceptualize their idea as what happens to #success. They must build a tangible explanation of the idea of ‘success’ that is frequently determined by their life experience. This research is aiming to investigate how the users from the entire world associate their thinking about ‘success’. This research used the descriptive qualitative method by having tweets as the main data gained from Twitter during 2018. The data were analysed by using domain analysis attached to Conceptual Metaphor in Cognitive Semantics approach. The discoveries of this investigation are success is book, success is building, success is degree, success is food, success is gift, success is iceberg, success is journey, success is product, success is profession, success is trade, and success is money.
Developing English Materials Using ESP Approach for al-Qur’an and Tafsir Study Program Students
Authors: Nurliana Nurliana
Published: November 2019

This study aimed at developing English materials using ESP approach for the first semester students of al-Qur’an and Tafsir Study Program at IAIN Palangka Raya in academic year 2018/2019. In this study, the model of materials development proposed by Sugiyono (2013:298) was adapted with the following steps: need assessment, reference of the research, development of English materials using ESP approach, expert validation, revision, try-out of the materials, revision, and final product. The instruments used consisted of questionnaire, observation, and interview. The data gathered was analyzed and described qualitatively. The students’ need based on the result of questionnaire was English materials using ESP approach. Considering that result, the English materials using ESP approach were developed and tried in 8 meetings. The data collected from try-out showed that the developed materials were applicable to the teaching-learning process and appropriate with the students’ need. Furthermore, the students responded positively toward the developed materials. They were active, motivated, and enthusiastic in doing the activities of the developed materials. English materials using ESP approach in the form of a textbook divided into eight units were the product of this study. The topics were Prayer, Fasting, Zakat, Muamalat, Food in Islamic Law, Property Right in Islamic Law, Inheritance in Islamic Law, and al-Qur’an and Science. The textbook was also supplemented with a list of vocabularies section, a list of regular verbs section, and a list of irregular verbs section.
Rhetorical Structures of English-Major Undergraduate Thesis Introduction Chapters
Authors: Indrian Ruth Dewi , Ardi Priyatno
Published: November 2019

Undergraduate students are required to write a thesis to obtain a degree. One of the most important chapters in the thesis is introduction. Introduction section plays an important role because it describes what the research is all about. To write an introduction chapter, Swales (1990) proposed Create-a-Research-Space (CARS) model, which include three moves, namely establishing a territory, establishing a niche, and occupying the niche. Every move consists of several steps. This study aims to analyze Swales’ CARS model in the introduction chapters of undergraduate theses written by English major students. Furthermore, the lexical and syntactical signals in each move and step are investigated. This research employed discourse analysis, which focuses on how texts are structured. The researchers analyzed 18 introduction chapters of undergraduate theses written by the English major students of Sanata Dharma University who graduated in 2017. In analyzing the corpus, the researcher used top-down analysis. The results showed that Move 1, Establishing a territory, appeared in the undergraduate theses. However, many of the students did not review the previous research. Move 2, Establishing a niche, was presented in three theses. In this stage, many of the students did not fill in the gap about the previous research. Move 3, Occupying the niche, was frequently used by the students. In this phase, the students outlined the purpose of their research. This study also found that the lexical and syntactical signals used in the theses were quite different from Swales’ CARS model.
Listening Materials for Vocational High School Students in Indonesia: Teachers’ Perception
Authors: Sularti Sularti , Drajati Nur Arifah , Supriyadi Slamet
Published: November 2019

Initially, communication is set up by listening. Students need the ability of listening skill for educational purposes and prepare themselves in social life. This study had the objective to investigate the perceptions of the teachers about the existing listening materials at the vocational high schools in Indonesia. In this study, the researcher engaged seventeen teachers of vocational high schools in Indonesia to be the participants. Data were collected by distributing a questionnaire then followed by an interview toward two participants. The results showed that listening materials met students’ needs, supported by the process of the scientific approach, were appropriate with the objective of the study and students' level of English, related to the syllabus of the 2013 curriculum model included the topic learned. On other hand, listening materials did not improve students’ ability in English, monotonous, made students having less focus, difficult to understand, difficult to build students’ prior knowledge, boring, and uninteresting. Finally, as the teachers’ view, the use of video could be the solution to the problems.
Teaching Practice is not Enough for EFL Teachers: Voices from IAIN Surakarta
Authors: Solikhah Imroatus , Budiharso Teguh
Published: November 2019

This study explores teaching practices for English Language Education program of IAIN Surakarta were implemented to link the gaps between theory and actual needs at schools. Relying on the qualitative approach, this study used content analysis as the main data sources, observation and interview to collect data.  The results of the study show that teaching practice for the ELT in IAIN Surakarta indicate restrictions.  With overall duration of 16 weeks, teaching practices at IAIN Surakarta is set in 6 credits, each of which consists of (1) micro teaching (2 credits), (2) administrative observation, (3) classroom observation, (4) classroom teaching practices.  During the field practices, complaints from mentor teachers appear that practican students are not well prepared in teaching skills and limited knowledge is performed to English competence performance in the classroom. Students claim that preparation in the itinerary of teaching practice they received from campus are not definitely sufficient as too many administrative processes are emphazised and mentoring system does not suffice to equip teaching skills
Effect of Various Pretreatments on Germination of Turkish Endemic Achillea gypsicola Hub.-Mor. Species under In Vivo and In Vitro Conditions
Authors: AÇIKGÖZ Muhammed Akif , KARA Şevket Metin
Published: November 2019

There has been an increasing interest to overcome seed dormancy in medicinal and aromatic plants using various pretreatments. This study was carried out to determine effect of several pretreatments on germination of Turkish endemic Achillea gypsicola Hub.-Mor. species under in vivo and in vitro conditions. The seeds were subjected to three pretreatments as various concentrations of GA3 and KNO3 and 91day cold stratification, with a seven-day interval. In vivo germination test produced no germination in the seeds pre-treated with cold stratification and various concentrations of GA3, whereas KNO3 treatments both in vivo and in vitro explicitly increased germination percentage. Cold stratification showed no inciting effect on germination both in vitro and in vivo conditions. In vitro combined application of KNO3 and GA3 produced higher germination percentages than single applications. The stimulating effect of KNO3 and GA3 on germination percentage increased as the duration of seed immersing in KNO3 increased. The seeds hold in 200 μM KNO3 for 48 hours and planted on MS medium supplemented with 2 mg L-1 GA3 showed 100% germination. In conclusion, this study suggested that combined pre-treatment of KNO3 with GA3 had a great potential in breaking seed dormancy and increasing germination of Turkish endemic Achillea gypsicola Hub.-Mor. species.
Reducing Atmosphere Packaging Technique for Extending the Shelf-life of Food Products
Authors: ALWAZEER Duried
Published: November 2019

Food processors generally apply different techniques to extend the shelf-life of food products according to the characteristics of the product. Modified Atmosphere Packaging (MAP) uses different gases in specific combinations to replace the air surrounding the product, which leads to minimize the undesirable oxidation reactions and microbial spoilage growth permitting extending the shelf-life of the product. The property of the Reducing Atmosphere Packaging (RAP) technique is the use of reducing gas like hydrogen besides other gases such as nitrogen, argon and carbon dioxide. The advantage of the presence of a reducing gas in the gaseous combination is the prevention of the oxidation reactions such as the formation of free radicals, the deterioration of vitamins such as C, E and beta-carotene, the deterioration of pigments such as carotenoids and the formation of off-flavors like the rancidity products. The prevention of the latter undesirable reactions aides to protect the freshness notes of the food products by preserving its natural color, taste and aroma, as well as the protection of the nutritional quality. The literature contains a few researches concerning the application of RAP on different food products. This is the first review reporting the potential application of hydrogen in modified atmosphere technology for extending the shelf-life of food products.
Benzotiyazol ve 1,3,4-Tiyadiazol İçeren Tek Kristalin Sentezi ve Teorik Olarak İncelenmesi
Authors: KARAKURT Tuncay , TAHTACI Hakan , ER Mustafa
Published: November 2019

Bu çalışmada tiyadiazol ve benzotiyazol halkası içeren 3-((5-amino-1,3,4-tiyadiazol-2-il)metil)benzo[d]tiyazol-2(3H)-on bileşiğinin yapısı, X-ışını kırınım yöntemi ve IR, NMR spektroskopik yöntemler kullanılarak aydınlatılmıştır. Deneysel çalışmalara destek olması amacı ile de B3LYP metodu ve 6-31G(d,p) temel seti kullanılarak teorik çalışmalar yapılarak bazı yapısal parametreler hesaplanmıştır. Özellikle kristalin reaktif bölgelerini incelemek için kısmi atom yükü ve moleküler elektrostatik potansiyel (MEP) ve Hirshfeld yüzey analizleri yapıldı. Son olarak da AIM yük analizi kullanılarak moleküller arası etkileşimlerin özellikleri incelenmiştir. Hesaplanan sonuçların, X-ışını verileriyle uyumlu olduğu görülmüştür.
Rize İli Merkez İlçesinde Konut Fiyatlarının Hedonik Fiyat Modeliyle Değerlemesi
Authors: GÜLER İsmet , BAŞER Uğur , BOZOĞLU Mehmet
Published: November 2019

Araştırmanın amacı, konuta ait fiziksel ve mekânsal özellikler kullanılarak Rize ili Merkez ilçesinde konut fiyatını etkileyen faktörleri belirlemektir. Araştırmanın verileri, Rize ili Merkez ilçesinde 2016 yılında konut alan 100 hane halkıyla yapılan anketlerden elde edilmiştir. Konut fiyatını etkileyen faktörlerin tespitinde hedonik fiyat modelinden yararlanılmıştır. Araştırma modeli, konut fiyatlarındaki değişimin %62.1’ini açıklayabilmektedir. Model sonuçlarına göre konutun net alanı, konut malzeme kalitesi, ısıtma sistemi, semtin sosyo-ekonomik düzeyi ve deniz manzarası konut fiyatını pozitif yönde etkilerken, konutun yaşı negatif yönde etkilemektedir. Konutun gerçekleşen alış-satış fiyatı ile model yardımıyla tahmin edilen konut fiyatı arasında ortalama %11.1’lik fark bulunmuştur. Bu sonuçlar, araştırma bölgesindeki konutların fiyatlarının tespit edilmesinde modelin kullanılabileceğini göstermektedir.
Güneydoğu Anadolu Bölgesindeki Üç Farklı İlin Üzümlerinin GC-FID Metoduyla Yağ Asitlerinin Karşılaştırılması
Authors: UMAZ Adil , GÜNGÖREN Muhammed , BARAN M. Fırat , ATALAR M. Nuri
Published: November 2019

Bu çalışmada Mardin, Diyarbakır ve Gaziantep kuru üzümlerinin yağ asit düzeyleri belirlendi. Mardin kuru üzümünün yağ asit düzeyleri ΣPUFA % 49.60, ΣMUFA % 29.61, ΣUSFA % 79.21 ve ΣSFA % 22.02 olarak, Diyarbakır kuru üzümünün yağ asit düzeyleri ΣPUFA % 22.80, ΣMUFA % 37.72, ΣUSFA % 60.58, ΣSFA % 40.45 ve Gaziantep kuru üzümünün yağ asit düzeyleri ΣPUFA % 44.77, ΣMUFA % 27.34, ΣUSFA % 72.12, ΣSFA % 28.62 olarak tespit edildi. Mardin ve Gaziantep kuru üzümünün linoleik asit (18:2n6c) düzeyi yüksek çıkarken Diyarbakır kuru üzümünün oleik asit (18:1n9c) ve palmitik asit (16:0) düzeylerinin yüksek çıktığı gözlendi.
Heterojen Katalizör Tasarımlı Biyodizel Üretimi
Authors: ÖZDEMİR Zafer Ömer , MUTLUBAŞ Halil
Published: November 2019

Biyodizel, hayvansal ve bitkisel yağların katalizör eşliğinde kısa zincirli alkoller ile (metil alkol gibi) transesterifikasyon reaksiyonu sonucu oluşan sıvı formlu bir yakıttır. Bu çalışmada mısır yağı kullanılarak biyodizel (Yağ Asidi Metil Esterleri) üretimi gerçekleştirildi. Biyodizel üretimi için kitosan biyopolimerinin –NH2 grubunun klasik ısıtma yöntemleriyle, farklı yapıdaki aminoasitlerin modifikasyonu sağlanarak heterojen katalizörler tasarlandı. Tasarlanan katalizörler ile biyodizel üretimi iki farklı şekilde gerçekleştirildi. İlk olarak geleneksel yöntemlerle biyodizel üretimi gerçekleştirildi. Daha sonra mikrodalga destekli biyodizel üretimi gerçekleştirildi. Elde edilen biyodizel yakıtlarının kalite kontrolü için; % verim testi, viskozite tayini, parlama noktası tayini, UV-VIS analizi, pH tayini ve yoğunluk analizleri yapıldı. Tasarlanan katalizörlerin biyodizel üretimindeki etkileri çizelgeler halinde gösterildi ve elde edilen sonuçlar TS EN 14214 yakıt standardına göre kıyaslandı. Üretilen biyodizel numunelerinin yakıt özelliklerinde iyileşme görüldü.
Malatya İlinde Kayısı Üretiminde Karşılaşılan Risk Kaynakları ve Uygulanabilecek Risk Yönetimi Stratejileri
Authors: Uçar Kubilay , ENGİNDENİZ SAİT
Published: November 2019

Bu çalışmanın amacı, Malatya ilinde kayısı üretiminde karşılaşılan risk kaynaklarını ve bu risklere karşı uygulanan risk stratejilerini belirlemektir. Araştırmada, Akçadağ, Darende ve Merkez ilçelerinde oransal örnekleme ile 159 kayısı üreticisinden anket yöntemiyle derlenen veriler analiz edilmiştir. Araştırmada öncelikle üreticilerin sosyo-ekonomik özellikleri incelenmiş, daha sonra kayısı üretiminin teknik ve ekonomik yönleri ortaya konulmuştur. Üreticilere göre risk kaynakları ve stratejileri beşli likert ölçeği ile değerlendirilmiştir. Araştırma sonuçlarına göre, kayısı üretiminde en önemli risk kaynakları sırasıyla; girdi fiyatları yüksekliği, iklim koşulları ve sulama koşullarıdır. Bu riskler için uygulanan en önemli risk stratejileri ise; satışların zaman dilimine yayılması, nakit sermayenin yüksekliği ve ürün sigortası olarak tespit edilmiştir.
Diagnóstico de los resultados obtenidos en las investigaciones por desaparición forzada en el contexto del conflicto armado
Authors: Vallejo Arango Diego Alejandro , Chala Francisco , Palacios Valencia Yennesit
Published: November 2019

La desaparición forzada de personas, si bien, no es un tema novedoso en el país, si constituye un asunto transcendental por la continua violación de derechos humanos que ha acompañado la historia colombiana. Por ello, presentar el diagnóstico de los resultados obtenidos en las investigaciones por desaparición forzada en el contexto del conflicto armado cobra vital importancia en este escenario.

Para el diagnóstico se observaron diferentes estudios en la materia, estableciendo directrices mínimas en la investigación del delito de desaparición forzada, acudiendo a la fundamentación de fuentes esenciales, entre ellas, los aportes presentados por el Centro Nacional de Memoria Histórica y a los lineamientos de la Corte IDH, como máxime interprete de la Convención Americana de Derechos Humanos. La propuesta desarrolla también, desde una perspectiva cualitativa, los elementos que se presuponen necesarios en la investigación del hecho punible y se estudian las necesidades penales, criminalísticas, político criminales y criminológicas esenciales, para la investigación de la desaparición forzada.

El paradigma en el cual se fundamenta la investigación está en armonía con la postura sociocrítica, sin desconocer el componente, propiamente normativo, que configura la desaparición forzada en el plano doméstico e internacional.
Información genética y derecho a la intimidad
Authors: De Torres Soto María Luisa
Published: November 2019

Es patente que, debido al avance de la tecnología y la medicina, se abren nuevos campos con los que el derecho a la intimidad y la vida privada deben relacionarse. Esta importancia surge por la aparición de nuevos hechos que tienen la consideración de intromisiones ilegítimas, concretamente, en lo relacionado con los datos genéticos de las personas. Tanto el Tribunal Europeo de Derechos Humanos, como nuestro Tribunal Constitucional han establecido una doctrina que sienta las bases para futuras actuaciones.El objeto de este trabajo es sistematizar y profundizar en los problemas jurídicos que pueden surgir en torno a la información que proporcionan dichos datos genéticos a la luz de la Jurisprudencia más reciente, así como recoger la nueva normativa europea al respecto sobre la Protección de Datos de carácter personal que entró en vigor el pasado 25 de mayo de 2018.
Nuda vida y estado de excepción en Agamben como categorías de análisis para el conflicto colombiano
Authors: López Herrera Juan Carlos
Published: November 2019

El presente artículo se propone reflexionar, a partir de los conceptos denuda vida y estado de excepción postulados por Giorgio Agamben, sobrelas particularidades del conflicto armado colombiano. El documento sedivide en tres partes: la primera aborda lo concerniente a la nuda vida entendidacomo producto de una racionalidad; la segunda parte se ocupa deanalizar en detalle la metáfora de la desnudez que entraña el concepto denuda vida; y la última parte analiza la excepcionalidad como elemento desubjetivación política. En el transcurso del desarrollo del texto, de maneratransversal, se articularán diferentes posiciones y puntos de vista que enriquecenel análisis de un fenómeno político como es el conflicto armadoque aún vive Colombia.
El defensor de familia en el proceso de adopción en Colombia
Authors: Ortiz Flórez Luz Astrid , Estrada Jaramillo Lina Marcela
Published: November 2019

El interés de este artículo es realizar a través de un estudio bibliográfico enel marco constitucional, legal, jurisprudencial y doctrinario la actuación delDefensor de Familia como responsable del proceso de adopción en Colombia.En este estudio se encontró que la Constitución Política, las Leyes 1098 de2006 y 1878 de 2018, y otros documentos normativos nacionales e internacionalesde obligatorio cumplimiento en el territorio nacional regulanlo relativo a éste proceso. Se logró evidenciar algunos vacíos legales yobstáculos de origen institucional, que dificultan al Defensor de Familiael ejercicio de su función dentro del proceso de adopción, debido a queobligan a su discrecionalidad y a retrasar el término en sus actuacionesadministrativas.
Mutación R249S TP53 en pacientes con cirrosis y carcinoma hepatocelular en un hospital de Medellín
Authors: Montoya-Guzmán Melissa , Duque-Jaramillo Alejandra , Gaviria-Calle Marcela , Hoyos Sergio , Restrepo-Gutiérrez Juan Carlos , Navas-Navas María-Cristina
Published: November 2019

Introducción: la exposición dietaria a la aflatoxina es un factor de riesgo para carcinoma hepatocelular, el cáncer primario de hígado más frecuente. Esta asociación se estableció gracias a la evidencia in vitro e in vivo de la relación entre la exposición a la aflatoxina B1 y la transversión G→T en el codón 249 del gen TP53, así como evidencia de la sinergia entre la aflatoxina y la infección crónica por virus de la hepatitis B.

Métodos: se determinó la frecuencia de la mutación R249S del gen TP53 en 30 pacientes con diagnóstico de cirrosis y/o carcinoma hepatocelular quienes fueron sometidos a trasplante hepático en un hospital en Medellín, Colombia. Se extrajo ADN a partir de las muestras de explante hepático, se amplificó el fragmento de interés y se detectó la mutación por polimorfismos de longitud de fragmentos de restricción.

Resultados: se encontró la mutación R249S en una de las 30 muestras analizadas (3,33 %) y se determinó, por medio de marcadores serológicos, infección por el virus de la hepatitis B en dos casos (6,67 %). No se encontró simultáneamente la mutación y la presencia de los marcadores de infección por virus de la hepatitis B.

Conclusión: los resultados sugieren una baja exposición dietaria con aflatoxina B1 en la población de estudio. Sin embargo, es importante tener en cuenta la regulación de los límites permisibles de aflatoxina B1 y la inclusión en el diagnóstico diferencial de carcinoma hepatocelular, dada la heterogeneidad de las condiciones de la población en diferentes regiones del país.