bluuebunny/crossref_metadata_2025 huggingface dataset:
TÜRKİYE’DE MÜDAHALELİ KLİNİK ARAŞTIRMALARDA SİGORTALAMA İŞLEMLERİ
Authors: İLBARS Hilal
Published: December 2022

Klinik araştırmalarda gönüllülerin hakları, güvenliği ve esenliği dikkate alınması gereken en önemli noktadır. Bunlar, bilimin ve toplumun çıkarlarından üstün tutulamaz. Bu nedenle, bizzat kendisinin veya kanuni temsilcisinin yazılı oluru alınmak suretiyle klinik araştırmaya iştirak edecek hasta veya sağlıklı kişilerden alınan bilgilendirilmiş gönüllü olur formu yanında özellikle gönüllülerin sigortalanması gerekir. Türkiye’de klinik araştırmalarda sigortalama işlemlerine yönelik hazırlanmış bir kılavuz mevcut olsa da sigorta poliçelerinin değerlendirilmesi, işlevselliği ve içeriği klinik araştırmaya katılan taraflarca doğru ve akılcı bir şekilde gerçekleştirilememektedir. Klinik araştırmalarda sigortalama işlemleri ile ilgili mevzuat ve bu konularda dikkat edilmesi gereken hususlara yer verilmeye çalışılmıştır, ayrıca bu konudaki tarafların kullanabilmesi için bir sigorta poliçesi kontrol listesi hazırlanmıştır.
Ultrasonography and laparoscopy as a diagnostic tool for evaluation of genitalia in cows
Authors: SOFI K A , SINGH M M
Published: December 2022

The present study was conducted for evaluating genitalia of cows (17) through transrectal ultrasonography (TRUS) and transabdominal laparoscopy (TAL) as a diagnostic tool. Genital tract of cows was initially examined by rectal palpation followed by TRUS and a day later TAL was conducted through flank approach.The study revealed: 35.3, 41.2 and 88.2% ovarian abnormalities; 5.8, 35.3 and 70.6% oviduct and adnexal abnormalities; and 23.6, 47.1 and 52.9% uterine abnormalities, by rectal palpation, TRUS and TAL, respectively. However, cervical abnormalities diagnosed were 35.3 and 52.9% by rectal palpation and TRUS respectively. TAL enabled to evaluate ovarian and oviduct and adnexal abnormalities accurately followed by TRUS than rectal palpation but ultrasound enabled to differentiate abnormalities like cystic ovaries, hydrosalpinx, pyosalpinx based on echogenicity compared to laparoscopy. However, TRUS proved to be very useful in diagnosing and differentiating uterine and cervical abnormalities compared to TAL and rectal palpation. It was concluded that both ultrasonography and laparoscopy are better diagnostic tools for evaluation of genitalia of bovines compared to rectal palpation and both these tools provided supplementary evidence in diagnosing and differentiating different genital abnormalities.
Effect of dietary supplementation of prebiotic on growth performance, immune response and intestinal microbial load in broiler chickens
Authors: MEESAM R , BISWAS A , NAMIT M , MANDAL A B
Published: December 2022

The experiment was conducted to study the effect of using prebiotic (mannan oligosachharide -MOS) in place of antibiotic growth promoter (AGP) on performance, immune response and intestinal microbial load in broiler chickens. Day-old broiler chicks (192) were randomly distributed into 20 groups each of 8 chicks (4 treatments Ã— 6 replicates). Four experimental diets T1, T2, T3 and T4 were formulated to contain no additive, bacitracin methylene di-salicylate (BMD) at 20 mg/kg diet, MOS at 0.1 and 0.2%, respectively. Body weight gain (g) was increased by the feeding of diets containing 0.2% levels of MOS, but feed intake (g), feed conversion ratio (FCR) and mortality (%) did not differ significantly. Antibody (28 d), titres were significantly higher after feeding 0.1 or 0.2% MOS and antibiotic (T2) supplemented group. During d 35, the response to intra-dermally injected phyto-hemagglutinin, an index of the in vivo cell-mediated immune response, was increased in the 0.2% MOS supplemented group. Significant reduction was observed in coliforms and total plate count in cecal (28 and 42 d) and excreta (42 d) in MOS (0.1 or 0.2%) or antibiotic (T2) supplemented groups. Lactobacillus count significantly increased in cecal (28 and 42 d) and excreta (42 d) in MOS @0.1 or 0.2% supplemented groups. Thus, it can be concluded that, 0.2% MOS with basal diet has a beneficial effect for growth performance, immune response and gut health status in broiler chickens, and MOS could be a good alternative to antibiotic growth promoter.
Vil øke befolkningens kunnskap om selvmordstematikk
Authors: Bekkevold-Jernberg Ina
Published: December 2022

Ett av tiltakene i regjeringens Handlingsplan for forebygging av selvmord er større åpenhet om selvmordsproblematikk og prosjektet som omfatter regionale folkeopplysningskampanjer med nasjonal overbygning om forebygging av selvmord er godt igang. Kampanjene skal bidra til å øke befolkningens kunnskap om selvmordstematikk, redusere stigma og å få flere til å søke hjelp. Målet er også at flere skal våge å handle dersom de er bekymret for noen. Nasjonal ressursgruppe består av personer fra ulikeregionale og nasjonale kompetansesentre og organisasjoner.
RESPUESTA VEGETATIVA DE PITAHAYA (Hylocereus spp.) A LA APLICACIÓN DE VERMICOMPOST Y FERTIRRIEGO
Authors: Morales-Ayala Yiruba , Ceja-Torres Luis Fernando , Méndez-Inocencio Carlos , Silva-García Teodoro , Venégas-González José , Pineda-Pineda Joel
Published: December 2022

Background. The pitahaya (Hylocereus spp.) in Mexico it is an endemic fruit with great adaptation to different environments and like a cactus requires little water. In Santiago Tangamandapio, Michoacan, Mexico, is a backyard crop and its intensive production is of recent introduction. The pitahaya, for its nutritional requirements can be adapted to conventional and organic management with fertilizers, however, the nutrition of the crop has been little investigated. Objective. The aim of this study was to evaluate the vegetative growth of pitahaya, in response to the application of vermicompost and fertigation. Methodology. Two experiments were established with species of Hylocereus undatus e H. ocamponis. For each species a design randomized with eight treatments and 10 replications was used. The eight treatments were vermicompost doses (0, 50, 100 and 150 t ha-1) with and without fertilization (200 mg· L-1 of N, P and K) in drip irrigation. The variables evaluated were the number of outbreaks and the total length of stems, assessed monthly, and the nutritional content of stem compound samples eight months after the plantation was established. Results. The plants with fertigation + 50 t ha-1 of vermicompost, and fertigation + 150 t ha-1 of vermicompost stimulated the highest production of shoots and stem elongation. In addition, the application combined of vermicompost and inorganic fertilizer had higher concentrations of potassium, calcium and nitrogen in stems. Implications. This study evaluated the vegetative stage, it continues with the study in stages of flower and fruit development; to have a complete knowledge of the management of these cultivars, in organic and conventional nutrition systems. Conclusion. Both species respond to the application of organic amendments and fertigation.
DINÁMICA DE LA COSECHA DE HUITLACOCHE (Ustilago maydis Cda.) EN NUEVE HÍBRIDOS COMERCIALES DE MAÍZ
Authors: Villanueva Verduzco Clemente , Escalante Pérez Cuauhtémoc , Villanueva Sánchez Evert , Sahagún Castellanos Jaime , Sánchez Cabrera Irma
Published: December 2022

Background. In contract farming, planned production is desirable. The planned artificial production of huitlacoche can be achieved by successive sowing dates to guarantee the continuous supply of the product throughout the year. Objective. To analyze the yield of huitlacoche and its harvest distribution through cutting in nine maize commercial hybrids. Methodology.  An experiment was carried out in a completely randomized design, with four replications in Chapingo State of México, México. Measurements of yield and quality (gall size) of the fungus were made in four cuts per hybrid during harvest. Results. In the nine hybrids studied, most of the harvest was concentrated in the second cutting. The Cronos and Dk-2042 hybrids (3,608 kg·ha-1 and 3,301 kg·ha-1, respectively) were the best in yield and quality of fungal galls and with contrasting distribution of their harvest. Implications. Hybrids Cronos and Dk-2042 can be used in an intensive and continuous production unit of huitlacoche. Cronos can be used to attend a daily demand of 1.5 t of fresh huitlacoche; while the Dk-2042 can be used to satisfy a weekly demand of 6 t, due to the respective overlaps of harvest among successive sowing dates. A surface of 14 ha is required, sowing 1 ha.week-1 of corn with a yield of 6 t.ha-1 to offer to the market 1.5 t.día-1 (Cronos hybrid) or 6 t.week-1 (Dk-2042 hybrid), depending on theirs contrasting distribution of the harvest among cutting. Conclusions. There are clear differences among the distribution of the harvested huitlacoche among commercial maize hybrids. The analysis of the yield per cutting allows to establish the varietal pattern of fungus harvest. Sequential plantings of complementary harvesting dynamics hybrids can be scheduled to serve continuous supply contracts.
INDIRECT SOMATIC EMBRYOGENESIS ON MUTANTS OF Agave tequilana WEBER CULTIVAR BLUE INDUCED WITH CO60 GAMMA RAYS
Authors: Espino Alejandro Angeles , Botín Alberto J. Valencia , Serrano Carlos Ramírez , Calleros Gil Virgen , Barrios Enrique Pimienta , Guzmán Eduardo Rodríguez
Published: December 2022

Background: Blue agave (Agave tequilana Weber var. azul), it is commonly known as “Agave azul or agave tequilero”. The Agave crop is fundamental part of the productive chain Agave-Tequila, since is the distinctive source of reducing sugars for the elaboration of the liqueur known as Tequila, according with the Appellation of Origen Tequila to fulfill the National Normativity (NOM-). Besides, Tequila is the most spirit drink exported from Mexico worldwide. According with the latest evaluation over this crop, the susceptibility to pathogens generate in cases total lost of the agave fields. Objective. to achieve somatic embryos that could be resistant, generated from plantlets irradiated with Co60gamma rays; which were obtained from axillary buds. Methodology: The arisen of embryo was reached in the modified Murashige and Skoog (MS) medium supplemented with of 2,4-D combined with BA or KIN. The plantlets were radiated 12 weeks after the somatic embryo induction with Co60 gamma rays. The doses were 0 (test control), 10, 20 and 30 Gy. Results: There was a significant difference in the induction of embryonic callus, development and mature somatic embryos, which were reduced as the doses of radiation increases. Since only somatic embryos were achieved in tissues treated with 10 and 20 Gy doses, in higher doses induction of embryonic callus was inhibited. The regression confirmed the negative results with the increase of radiation. Implications: There were made protocols to achieve somatic embryos and plants from tissues irradiated with 10 and 20 Gy. Conclusions: The radiation effect over somatic tissue was crucial as the doses affect the conversion into plantlets, nevertheless such radiation allowed the conversion of the embryos to complete agave plantlets
The Effect of Capital Structure on the Performance of Selected Conglomerates in Nigeria
Authors: John John Ime
Published: December 2022

This study focused on the effect of capital structure performance in Nigeria conglomerates. It sought to assess the significance of capital structure, and to suggest measures that could enhance its effectiveness and firms’ performance in Nigeria. To achieve the objective of the research, some financial and performance indicators, using an ex-post facto research design was applied. The population of the study comprised of six (6) firms. The data was collected, analyzed and tested using the descriptive statistics and the panel data analysis techniques. From the analysis, it was revealed that there was a significant relationship between debt ratio and conglomerates performance in Nigeria. Also, it was revealed that long term debt to capital employed had a significant influence on conglomerates performance in Nigeria. Furthermore, total debt ratio was found to have a significant effect on conglomerates performance in Nigeria. Based on the findings, the study recommended that the management of Nigerian conglomerates should work very hard to optimize their capital structure, in order to increase the financial performance. They can do that through ensuring that the debt proportion (debt ratio) in their capital structure is optimal. Also, the Management of Nigerian conglomerates should increase their commitments into long term debt to capital employed, in order to improve financial performance from their business operation.
Exploring the Effects of Screencast Feedback on Writing Performance and Perception of Chinese Secondary School Students
Authors: Xie Xingxing , Che Lingying , Huang Hongxi
Published: December 2022

Feedback has a pivotal role in language and literacy learning. With the ubiquity and advancement of technology, screencast feedback (SF) has emerged as a novel mode of feedback in the context of English as a foreign language (EFL) writing classrooms. Yet, there remains a paucity of evidence on the effects of SF on enhancing students’ English writing performance, particularly in Chinese secondary school settings. Thus, the current study aims to employ a mixed-method sequential explanatory design to investigate the impacts of SF on the writing performance of Chinese secondary school students and their perceptions toward SF. The sample consisted of 90 intermediate Grade 12 high school students from Southern China. While the experimental group received the SF, the control group received conventionally written feedback in their argumentative writings. Quantitative findings indicated that the posttest of the experimental group participants in terms of task achievement and coherence and cohesion in writing was higher than their pretest; however, there was no significant difference in enhancing lexical resources and grammatical range accuracy. Results also showed that the experimental group excelled over the control group regarding overall writing performance. Qualitative findings from semi-structured interviews in the experimental group revealed that most participants maintained positive perceptions of SF, as it strengthened student-teacher interaction, provided specific and longer feedback, and promoted students’ confidence.
Influence Factors and Prediction of ICT Application Ability in Post-Epidemic Era in China
Authors: Wang Ningjing
Published: December 2022

In the spring of 2020, the new coronavirus pneumonia epidemic struck, and the development process of many industries was pressed the pause button, but the shortcut button was pressed for informatization education. The nationwide delay in the start of school, and the ensuing large-scale, high-frequency as well as all-round online teaching, all posed challenges and opportunities for teachers. In this context, based on the current situation of teachers’ information technology application ability in the post-epidemic era, this study attempts to explore the impact of online teaching on teachers’ information technology application ability during the epidemic. At the same time, it looks for the factors of problem exploration, and proposes strategies to help teachers improve the ability of information technology application, aiming to provide some basis and reference for schools and teachers to meet the improvement of information technology application ability in the post-epidemic era.
Exploration on English Literature Teaching Model Based on the College Students' Mental Health
Authors: Gao Ying
Published: December 2022

Shaping students' sound and wholesome personality is the most basic requirement of the talents developing in Chinese colleges, and promoting students' good psychological qualities is also an important aim of carrying out ideological and political education in colleges and realizing the education goal of moral cultivation. The process of learning English literature is also an emotional experience process of feeling, understanding, evaluation and aesthetic. Reading, studying and appreciation of literary works can play a positive role in maintaining students' mental health problems, which can help to correct, adjust and even cure some psychological problems. Based on the current situation of college students' mental health, this paper analyzes the psychological care function of English literature course, introduce the psychotherapeutic function of literature and explores how to integrate psychological care function into the teaching process.
Evaluación de impacto ambiental y proyectos de parques eólicos: balance de intereses, Red Natura 2000 y aspectos procedimentales
Authors: García Ureta Agustín
Published: December 2022

Este trabajo analiza la aplicación del procedimiento de evaluación de impacto ambiental en el caso de los parques eólicos. Las energías renovables han recibido una atención preferente en los últimos tiempos debido a la lucha contra el cambio climático. Sin embargo, tales instalaciones no están exentas de efectos ambientales sobre otros bienes jurídicos que deben ser protegidos. Por ello, este trabajo analiza el balance de intereses que los jueces llevan a cabo, los requisitos procedimentales del procedimiento de evaluación, junto con la afección a las zonas de la red Natura 2000.
Integrated Financial Governance Model with Budget Realization Information System
Authors: Priharta Andry , Gani Nur Asni , Jaharuddin Jaharuddin , Utama Rony Edward , Darto Darto , Maulianza Medo , Ananto Tri
Published: December 2022

The research aims to identify the inhibiting factors for budget implementation and improve financial management through the development of an information system on budget realization at Universitas Berbasis Teknologi Modern (Modern Technology Based University - UBTM), a university in Banten focusing on modern technology. This is an applied research type with primary data obtained through focused group discussion using fishbone diagram analysis involving eleven informants. Based on the research, conditions and recommendations for improvement have been identified, which will then be prepared for the budget management flow process as the basis for preparing the budget realization information system. This system has set a monthly budget execution schedule, adequate internal control, and identified 34 work units with 91 users involved.
Employee Performance in terms of Compensation and Work Motivation
Authors: Dewi Maria Aletta
Published: December 2022

This study aims to determine and analyze the effect of compensation and work motivation on employee performance at Santika Pekalongan Hotel. The population of this study were employees of the Santika Pekalongan hotel with a total of 73 respondents. The sampling technique in this study used a census. This analysis includes validity, reliability, multiple linear analysis, t test, f test, coefficient of determination analysis.

The results of this study indicate that compensation (X1) has a positive but not significant effect on employee performance, work motivation (X2) has a positive and significant effect on employee performance
BELEDİYE İŞÇİLERİNİN HUKUKİ STATÜSÜNE DAİR SORUNLAR VE İSTİHDAMA YANSIMALARI
Authors: ÇINAR Sinan
Published: December 2022

Kamu hizmetlerinin özelleştirildiği, güvencesiz çalışmanın yaygınlaştığı, memur eli ile yürütülmesi gerektiğine inanılan/savunulan pek çok kamu hizmeti ve kamu görevinin işçiler eli ile yürütüldüğü günümüzde özellikle belediye işçilerinin kamu personel rejimi içerisindeki yeri tartışma konusu olmaya devam etmektedir. Bu çalışmada özellikle son yirmi beş yıllık süreçte hayata geçirilen ve kamuda çalışma hayatını etkileyen yasal düzenlemeler ile yargı kararları birlikte değerlendirilerek belediye işçilerinin özellikle idare hukuku ve ceza hukuku karşısındaki durumu tartışma konusu yapılacaktır. Bu yapılırken öncelikle işçiler eli ile yürütülen belediye hizmetlerinin/görevlerinin niteliği belirlenmeye çalışılacak, sonrasında belediyelerdeki istihdam rejiminin genel hatları ortaya konulduktan sonra mahkeme kararları, öğretideki görüşler ve kurum görüşleri değerlendirilerek belediye işçilerinin personel rejimi içerisindeki yeri tanımlanmaya çalışılacaktır. Bu kapsamda günümüzde yaşanan değişimleri yadsımadan hukukun önemli kavramlarından biri olan kamu görevlisi kavramının yeniden tanımlanması gerekmektedir. Değerler dizisinde yaşanan değişim dikkate alındığında asli ve sürekli kamusal hizmetleri yerine getiren belediye işçilerinin kamu görevlisi tanımı içerisinde kabulü kanımızca daha doğru olacaktır.
Practicality of Learning Devices Based on Conceptual Change Model to Improve Concept Mastery of Students in the Gas Kinetic Theory Material
Authors: Susilawati Susilawati , Kusumayati Baiq Arum , Sutrio Sutrio , Doyan Aris
Published: December 2022

This study aims to determine the practicality of learning devices based on conceptual change model to improve concept mastery of students in the gas kinetic theory material. The device was developed with a 4D model consisting of define, design, develop, and disseminate. The learning tools developed are in the form of syllabus, lesson plan, student worksheet, and concept mastery instrument. The data collection was carried out through the distribution of student response questionnaires and observation sheets on the implementation of learning in the eleventh grade MIPA SMAN 1 Kediri. The questionnaire score used consisted of 4 scales, namely a scale of 4 (very good), a scale of 3 (good), a scale of 2 (less), and a scale of 1 (very less). The results showed that the response of students and the implementation of learning were very practical. Based on these data, it can be concluded that the learning device conceptual change model practically to improve concept mastery of students in the gas kinetic theory material
Existence of positive solutions for a nonlinear semipositone boundary value problems on a time scale
Authors: Panigrahi Saroj , Rout Sandip
Published: December 2022

In this paper, we are concerned with the existence of positive solution of the following semipositone boundary value problem on time scales: \begin{equation*} (\psi(t)y^\Delta (t))^\nabla + \lambda_1 g(t, \,y(t)) + \lambda_2 h(t,\,y(t)) = 0, \,t \in [\rho(c), \,\sigma(d)]_\mathbb{T}, \end{equation*} with mixed boundary conditions \begin{equation*} \begin{split} \alpha y(\rho(c))-\beta \psi(\rho(c)) y^\Delta(\rho(c))=0,\\ \gamma y(\sigma(d))+\delta \psi(d) y^\Delta(d)=0, \end{split} \end{equation*} where $\psi:C[\rho(c),\, \sigma(d)]_\mathbb{T}$, $\psi(t)>0$ for all $t \in [\rho(c),\,\sigma(d)]_\mathbb{T}$; both $g$ and $h : [\rho(c),\,\sigma(d)]_\mathbb{T} \times [0,\,\infty) \to \mathbb{R}$ are continuous and semipositone. We have established the existence of at least one positive solution or multiple positive solutions of the above boundary value problem by using fixed point theorem on a cone in a Banach space, when $g$ and $h$ are both superlinear or sublinear or one is superlinear and the other is sublinear for $\lambda_i>0;\,i=1,\,2$ are sufficiently small.
Efficacy of antioxidant in the therapy of subclinical mastitis in buffaloes
Authors: Kala Salikineedi Rupa , Rani Nalluri Lakshmi , Rao Velamala Vaikunta , Subramanyam Kothapalli Venkata
Published: December 2022

This study was conducted to assess the therapeutic efficiency of antioxidant in subclinical mastitis. Therapeutic trials were conducted in twelve buffaloes affected with subclinical mastitis and were randomly divided into two groups. The buffaloes of Group 1 were treated with intramuscular injection of Inj. Mofoi 5 mg/kg body weight, while Group 2 buffaloes were treated with intramuscular administration of Inj. Mofoi 5 mg/kg body weight along with antioxidant powder orally. The therapeutic efficacy was assessed based on bacteriological cure and the pre and post therapeutic values of somatic cell count, electrical resistance, pH and milk yield. The use of antioxidant along with Moxifloxacin was found to be superior than antibiotic alone by improving udder's natural defence mechanism, early restoration of milk yield and quick recovery.
Efficacy of certain intrauterine immunomodulators in management of endometritis in postpartum graded Murrah buffaloes
Authors: Venkatesh Derangula , Venkataramana Kudikilla , Ramsingh Lakavath , Swathi Bommu
Published: December 2022

The present study is conducted to evaluate the efficacy of certain immunomodulators on recovery and conception rate in post partum endometritic buffaloes. Total 50 buffaloes were selected for the study and randomly divided into five groups. The buffaloes of Group 1 were given with a single dose of 100 μg E. coli lipopolysaccharide as intrauterine, Group 2 buffaloes were treated with a single dose of 2 mg Lysozyme, Group 3 was treated with 4 g of Cephalexin for three consecutive days. While, Group 4 buffaloes were treated with a single dose of 2 mg Lysozyme + 4 g of Cephalexin and Group 5 was treated with 30 ml of normal saline and was kept as control. All therapeutics were infused into the uterus after dissolving in sterile water. The efficacy of treatment was assessed by declines in bacterial load and PMNL cell count after treatment. The overall conception rate was 88.88, 71.42, 66.66, 75.00 and 33.33% in Group 1, 2, 3, 4 and Group 5, respectively.
Hydrallantois in a graded Murrah buffalo - A case report
Authors: Annadurai Thangamani , Manda Srinivas , Borra Chandra Prasad , Kavuri Sadasiva Rao
Published: December 2022

A 8 years old graded Murrah buffalo during the eighth month of gestation was presented with the history of sudden, progressive and symmetrical distension of abdomen during the previous 10 to 12 days. The buffalo underwent a medical termination of pregnancy with Inj. Cloprostenol Sodium and Inj. Dexamethasone. At 96 h post-treatment, rupture of fetal membrane resulted in gushing out of more than 100 to 120 litres of amber coloured allantoic fluid from the uterus. A dead female fetus was delivered by gentle traction. The animal was treated with oral ecbolics and parenteral administration of fluids and antibiotics for 5 consecutive days. The buffalo had an uneventful recovery.
Comparison of parasitological, serological and molecular diagnostic tests for detection of subclinical Trypanosomosis in two organised dairy herds
Authors: Charaya Gaurav , Rakha Naresh Kumar , Kumar Aman , Gupta Akhil Kumar , Maan Sushila , Singh Ajit , Goel Parveen
Published: December 2022

Trypanosomosis also known as ‘Surra’ caused by Trypanosoma evansi is of significant economic importance in livestock production. Diagnosis of subclinical infection and carrier state of disease is far difficult. Therefore, the present study was conducted to compare parasitological, serological and molecular diagnostic tests for detecting subclinical trypanosomosis in two dairy herds of Murrah buffalo (n=27) and crossbred cattle (n=22) in Hisar district of Haryana. Peripheral blood samples collected from all the animals were subjected to blood smear examination and DNA isolation for molecular detection by PCR, and like-wise serum samples were collected and subjected to latex agglutination test (TE-LAT) for T. evansi antigen detection. PCR products from positive samples were purified and sequenced for confirmation of T. evansi DNA. None of the animals in the two herds was found positive for T. evansi parasites by microscopic examination of thick blood smears. In buffalo farm, 29.62% samples each were found moderately and weak positive by TE-LAT, whereas PCR assay test yielded 40.74% samples positive for T. evansi DNA. In cattle farm, TE-LAT showed 18.18%, 31.89% and 9.09% samples to be strong, moderate and weak positive, whereas 50% samples were found PCR-positive for T. evansi DNA. Agreement among TE-LAT and PCR assay, as expressed by the kappa value, was found to be poor. To conclude, each test has its own merits and limitations. While TE-LAT is suitable for screening purpose, PCR assay confirms parasite in blood. For clinical diagnosis, results of laboratory diagnostic tests must, however, be correlated clinically before initiating the therapy.
Prevalencia de fibrosis hepática estimada por predictor no invasivo en una población de pacientes con Diabetes Mellitus Tipo 2
Authors: Fustamante-Flores Jaime , Espinoza-Portocarrero Miguel , Montes-Teves Pedro
Published: December 2022

Actualmente la enfermedad por hígado graso no alcohólico (HGNA) es un problema de salud pública; que es definida como la presencia de esteatosis macrovesicular en > 5% de los hepatocitos, en ausencia de consumo significativo de alcohol. Es considerada como la manifestación hepática del síndrome metabólico y engloba en realidad a dos tipos de enfermedades con pronósticos distintos: la esteatosis simple y la esteatohepatitis no alcohólica, la primera de ellas con una evolución por lo general benigna, en tanto la segunda se asocia al desarrollo de fibrosis y riesgo de desarrollar cirrosis hepática y hepatocarcinoma, siendo la diabetes mellitus un factor de riesgo para desarrollo de estas complicaciones. Nuestro objetivo fue determinar la prevalencia de fibrosis hepática estimada mediante métodos no invasivos en una población con diabetes mellitus del programa cuídate de la Clínica Internacional. Materiales y métodos: Se realizó un estudio de tipo analítico transversal. Este estudio se registró los datos de pacientes obtenido de la base del programa Cuídate de la clínica internacional sede Lima, durante el año 2021. Se procedió a revisar las historias clínicas de los cuales se obtuvieron los datos de sexo, edad, resultados de laboratorio: niveles de plaquetas, AST (aspartato aminotransferasa), ALT (alanina aminotransferasa). Luego se procedió a calcular el score no invasivo FIB-4. Resultados: Se seleccionaron 235 pacientes, de los cuales 58.7% (138) fueron de sexo masculino, mientras que 41.27% (97) fueron de sexo femenino; con una edad promedio de 57.6 años. El 80.85 % (190) de los pacientes tuvieron un IMC mayor a 25 Kg/m2. Se estimó fibrosis significativa (F2) mediante cálculo de FIB-4 que fue de 28.9% (68) y de fibrosis avanzada que fue de 2.97% (7) de los pacientes. Conclusiones: Los pacientes con diabetes mellitus tipo 2 del Programa cuídate tienen una prevalencia e timada mediante predictor no invasivo FIB-4 de fibrosis hepática significativa de 28.9% y de fibrosis avanzada de 2.97%.
Escala NEWS como predictor de mortalidad en pacientes con COVID-19
Authors: Francia Martín , Bernui-Bobadilla Faria , Ayala-García Ricardo
Published: December 2022

El COVID – 19 fue desafiante para las instituciones de salud, por ello es necesario disponer de un sistema de puntuación para la alerta temprana y predecir un resultado adverso en pacientes con COVID – 19 admitidos en emergencia. Nuestro objetivo fue obtener evidencia para apoyar el uso de la puntuación de alerta temprana (NEWS) que permita identificar a los pacientes con riesgo de deterioro clínico. Realizamos un estudio observacional retrospectivo con 222 pacientes admitidos por emergencia con COVID – 19, se analizó el puntaje NEWS para verificar la correlación con la mortalidad y requerimiento de UCI. El 48.6% obtuvo una puntuación de riesgo alto, donde el 10.2% fallecieron, 25.9% fueron admitidos en UCI. La escala de NEWS se basa en parámetros medibles desde el triaje, sin embargo; no se encontró correlación con el desenlace o requerimiento de UCI, pues existen otros factores que contribuyen al peor resultado clínico de los pacientes con COVID – 19.
Prevalencia de ansiedad y depresión utilizando la escala de ansiedad y depresión (HADS) en pacientes con Síndrome de Intestino Irritable
Authors: Príncipe-Meneses Fortunato S. , Cabanillas-Ramirez Cielo , Llave-Sangiacomo Barbara , De La Barrera-Cantoni Sol J. , Fustamante Flores Jaime , Espinoza Portocarrero Miguel , Oyanguren Miranda Pedro
Published: December 2022

Introducción: en ausencia de una anormalidad estructural. Es una de las enfermedades que se ha asociado frecuentemente con enfermedades psiquiátricas como ansiedad y depresión. El objetivo del estudio fue determinar la prevalencia de depresión y ansiedad en pacientes con SII empleando la encuesta Hospital Anxiety and Depression Scale (HADS) en pacientes que acuden a consultorio de gastroenterología en la Clínica Internacional Sede Lima (CILM). Materiales y Métodos: Estudio descriptivo no comparativo en el cual se utilizaron encuestas autoaplicadas en consultorio externo de la CILM. Se utilizó Microsoft Excel para tabular y STATA versión 17 para calcular las frecuencias absolutas y relativas. Resultados: Se incluyó a 67 pacientes: sexo: femenino (77.61%), rango de edad: 36-45 años (56.72%) y variedad de sintomas en SII: estreñimiento (55.22%). La prevalencia de ansiedad fue de 71.64% mientras que la de depresión fue de 26.87%. Conclusiones: Los p cientes con SII tuvieron mayor prevalencia de síntomas compatibles con ansiedad en comparación con depresión.
Manifestaciones gastrointestinales en el sindrome post covid agudo: Revisión de la literatura y su impacto en la actualidad
Authors: Necochea Cacho Isaac A.
Published: December 2022

El síndrome post COVID-19 (o post COVID agudo) se caracteriza por la persistencia o prolongación de síntomas durante más de 4 semanas después de la infección inicial por SARS-CoV-2. La prevalencia del síndrome post COVID-19, va del 10% al 87% en los pacientes que tuvieron COVID-19. Este síndrome fue descartado inicialmente por muchos, pero ahora se la reconoce como una enfermedad multiorgánica, la cual refleja un desafío constante en la atención médica. Existen factores neuropsiquiátricos que, asociados a la inflamación del tubo digestivo y la activación del sistema nervioso entérico, son los mecanismos potenciales para el desarrollo del Trastorno de la Interacción Intestino Cerebro (DGBI) Post COVID agudo.
Pseudoaneurisma ventricular izquierdo gigante: utilidad de la imagen multimodal
Authors: Baltodano-Arellano Roberto , Cachicatari-Beltran Angela , Cupe-Chacalcaje Kelly , Villanueva-Pérez Fernando
Published: December 2022

Presentamos el caso de un paciente de 76 años con historia de hipertensión arterial y tabaquismo, quién acude para evaluación por disnea y dolor torácico de tres semanas de evolución. El electrocardiograma mostró signos de necrosis en cara inferior. Con imagen multimodal se hizo el diagnóstico de Pseudoaneurisma ventricular gigante y se decidió por la corrección quirúrgica, lastimosamente el paciente falleció de Neumonía por SARS-CoV-2.
Esofagitis herpética en un paciente inmunocompetente
Authors: Necochea Cacho Isaac A. , León Moreno Julio F.
Published: December 2022

La esofagitis herpética usualmente ocurre con mayor frecuencia en pacientes inmunodeprimidos, sin embargo, también ha sido documentada en pacientes inmunocompetentes, aunque de manera infrecuente. En pacientes inmunocompetentes suele deberse a la primoinfección por el virus del herpes simple, usualmente el tipo 1. El cuadro clínico suele ser de inicio agudo y estar caracterizado por la tríada de odinofagia, dolor retroesternal y fiebre. El diagnóstico se basa en los hallazgos de la videoendoscopia digestiva alta y en la toma de biopsias para el estudio de anatomía patológica e inmunohistoquímica. El curso usualmente es benigno y el inicio del tratamiento antiviral de manera precoz permite lograr la rápida desaparición de los síntomas y limitar la severidad de la infección.
Edukasi Masyarakat Pulau Pajjenekang Dalam Pengembangan Desa wisata Di Kabupaten Pangkajene Dan Kepulauan
Authors: Ningsih Sri Ningsih
Published: December 2022

Pajjenekang Island has its own tradition in commemorating the Islamic New Year and the anniversary of their island. The tradition of traditional art attractions of the Pajenekang Island community called tammung Taung has existed since before Indonesia's independence long at the beginning of the 20th century, in order to celebrate the freedom of the figures on Pajenekang Island. Besides being rich in traditions, Pajenekang Island has environmental problems, namely cleanliness problems, the absence of facilities. waste management makes there is still garbage thrown into the sea. Implementation of this community service with the method of providing education through lecture and question and answer mechanisms. The results of this activity are very useful for increasing the knowledge and skills of the community. The results of the evaluation during the activity process showed that the community had understood and knew how to develop a tourist village on Pajjenekang Island. With this educational activity, it is hoped that it will be able to increase public knowledge so that they can develop the village so that Pajjenekang Island can be achieved as a Tourism Village in South Sulawesi.
Pulmonary hypertension associated with left-sided heart disease
Authors: Maeder Micha T. , Schoch Otto D. , Kleiner Rebekka , Joerg Lucas , Weilenmann Daniel , Swiss Medical Weekly
Published: December 2022

Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD.
Comparison of metabolic outcomes in patients undergoing laparoscopic roux-en-Y gastric bypass versus sleeve gastrectomy – a systematic review and meta-analysis of randomised controlled trials
Authors: Hayoz Christelle , Hermann Thierry , Raptis Dimitri Aristotle , Brönnimann Alain , Peterli Ralph , Zuber Markus
Published: December 2022

BACKGROUND AND OBJECTIVES
Bariatric surgery is the most effective treatment for morbid obesity and is known to have beneficial effects on glycaemic control in patients with type 2 diabetes mellitus (T2DM) and in diabetes prevention. The preferred type of surgery and mechanism of action is, however, unclear. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing the effects of laparoscopic roux-en-Y gastric bypass (RYGB) with those of sleeve gastrectomy (SG) on metabolic outcome, with a special focus on glycaemic control.

METHODS
A literature search of the Medline, Pubmed, Cochrane, Embase and SCOPUS databases was performed in November 2014 for RCTs comparing RYGB with SG in overweight and obese patients with or without T2DM. The primary outcome was improvement in postoperative glycaemic control. Secondary outcomes included weight-related and lipid metabolism parameters. Synthesis of these data followed established statistical procedures for meta-analysis.

RESULTS
Sixteen RCTs with a total of 1132 patients with overweight or obesity were included in the analysis. When compared with patients who underwent SG, those who underwent RYGB showed no difference after 12 months in mean fasting blood glucose (mean difference [MD] −6.22 mg/dl, 95% confidence interval [CI] −17.27 to 4.83; p <0.001). However, there was a better outcome with RYGB, with lower mean fasting glucose levels at 24 months (MD −16.92 mg/dl, 95% CI −21.67 to −12.18), 36 months (MD −5.97mg/dl, 95% CI −9.32 to −2.62) and at 52 months (MD −15.20 mg/dl, 95% CI −27.35 to −3.05) mg/dl; p = 0.010) and lower mean glycated haemoglobin (HbA1 at 12 months (MD −0.47%, 95% CI −0.73 to −0.20%; p <0.001) and at 36 months postoperatively compared to SG. Fasting insulin levels and HOMA indices showed no difference at any stage of follow-up. In the subgroup including only diabetic patients HbA1c showed lower levels at 12 months (MD −0.46%, 95% CI−0.73 to −0.20%). No difference was found for the fasting insulin at baseline and after 12 months. Similarly, when compared to SG, patients that underwent RYGB had lower low-density lipoproteins at 12 months. This effect was lost at 36 months. Patients undergoing RYGB also had lower triglycerides at 12 months and at 52 months, lower cholesterol at 60 months and an improvement of BMI at 52 months postoperatively. BMI values at 12 months and low-density lipoprotein levels at 12 and 36 months were lower for diabetic patients only, as in the overall analysis.

CONCLUSION
Based on this meta-analysis, RYGB is more effective than SG in improving weight loss and short- and mid-term glycaemic and lipid metabolism control in patients with and without T2DM. Therefore, unless contraindicated, RYGB should be the first choice to treat patients with obesity and T2DM and/or dyslipidaemia.
IoT Impact in textiles management
Authors: SILVESTRU Cătălin-Ionuț , FIRULESCU Alexandru-Cristian , IORDOC Dumitru- Georgian , SILVESTRU Ramona-Camelia , GRECU Andreea
Published: December 2022

Textiles are a sophisticated and ancient technology with many appealing qualities. They are frequently soft and are readily folded, twisted, sliced, or deformed. When under tension, textiles can hold their shape and can even be manufactured to have different degrees of stretchability. Smart
wearables and IoT-based clothing have the potential to have a significant impact by balancing functionality and the joy that fashion brings, along with the rise of the Internet of Things (IoT). It is now possible to easily fabricate both soft materials with embedded flexibility and stiff objects with
embedded flexibility by combining textiles and 3D printing. In order to reinvent technology that can anticipate wants and desires, smart clothing tries to strike a balance between engineering, cybersecurity, interface, fashion, user experience, design, and science. The increasing merging of
textiles and electronics now allows for the seamless and widespread integration of sensors into textiles, and conductive yarns have been developed to make this possible.
Standards regarding integrated reporting in the context of modelling the performance concept
Authors: POPA Elena
Published: December 2022

The evaluation of companies' progress towards sustainability and the integrated reporting associated with it was supported by multiple proposals, which took the form of methods, conceptual frameworks, standards, ratings, indexes, awards, accreditations, awards, alliances, studies, and research. The present study highlights the perspective of aligning the integrated reporting standards in the context of the transition to the new business models of the future. In order to shape the concept of performance, it is important to implement the process of reducing the gap regarding the integrated reporting of companies and the adoption of standards regarding the reporting of non-financial information in an integrated way, unanimously accepted and assumed.
Organizations in change: a short correlational analysis of a few motivational practices and the organizational agility
Authors: VOICA Orlando Marian , SILVESTRU Ramona-Camelia
Published: December 2022

Our research examines some organizations that have implemented change in order to identify relevant
motivational practices that can be used by organizations that intend to involve themselves in an organizational change
endeavour. The research investigate the existing correlations between the organizational ability to reconfigure its’ resources according to the changing demands of the environment and some organizational practices in the sphere of individual motivation, specific to proactive or reactive organizations.. The analysis was based on data collected through a questionnaire whose respondents were directors, managers and consultants directly involved in a change initiative within a Romanian
organization and who had extensive knowledge about change processes and their results. Our results aim to support the continuous improvement of organizational change processes, revealing some motivational aspects with impact on the organizational agility
Image and Texture Independent Deep Learning Noise Estimation Using Multiple Frames
Authors: Kirmizitas Hikmet , Besli Nurettin
Published: December 2022

In this study, a novel multiple frame based image and texture independent Convolutional Neural Network (CNN) noise estimator is introduced. Noise estimation is a crucial step for denoising algorithms, especially for ones that are called “non-blind”. The estimator works for additive Gaussian noise for varying noise levels. The noise levels studied in this work have a standard deviation equal to 5 to 25 increasing 5 by 5. Since there is no database for noisy multiple images to train and validate the network, two frames of synthetic noisy images with a variety of noise levels are created by adding Additive White Gaussian Noise (AWGN) to each clean image. The proposed method is applied on the most popular gray level images besides the color image databases such as Kodak, McMaster, BSDS500 in order to compare the results with the other works. Image databases comprise indoor and outdoor scenes that have fine details and richer texture. The estimator has an accuracy rate of 99 % for the classification and favourable results for the regression. The proposed method outperforms traditional methods in most cases. And the regression output can be used with any non-blind denoising method.
Sea State Characterization Using Experimental Synthetic Aperture Radar Raw Data in Two-Dimensions and the Modified Fractal Signature Method
Authors: Kotopoulis Apostolos , Massinas Basil , Pouraimis Georgios , Frangos Panayiotis
Published: December 2022

This paper presents a novel method for the characterization of the sea state using a set of raw experimental Synthetic Aperture Radar (SAR) data in two dimensions, i.e., in the “fast time” and “slow time” directions (as explained in the text) and the so-called “Modified Fractal Signature” (MFS) method. That is, experimental SAR radar signatures in the above two dimensions (i.e., “raw data” in the time domain) were provided to our research group by the Norwegian Institute of Defence (FFI Institute), Norway, which we processed and analyzed using the MFS method in a novel way, as presented in detail in this paper. The numerical results obtained here show an easy categorization of the sea surface as “calm sea” or “turbulent sea”, thus establishing a very promising technique for the characterization of sea state in real time, as described in detail in the text.