bluuebunny/crossref_metadata_2025 huggingface dataset:
Seismic Behavior of RC Building with and Without Buckling Restrained Braces
Authors: Teruna Daniel Rumbi
Published: September 2022

Nonlinear analysis for evaluating seismic performance of building under seismic excitation requires nonlinear properties of any component that are quantified by strength and deformation capacities. The nonlinear behavior of beams and column components are modeled in the form of plastic hinges as described in ASCE41-13 [1] guideline. This document provides the hinge rotation capacity for several ranges of detailing assumption. Buckling restrained braces (BRB) can be modeled as a link element with force-deformation behavior through Wen’s plasticity model. This paper evaluates possible differences of seismic performance of six-story reinforced concrete moment resisting frame with conforming and non-conforming plastic hinge rotation, with and without BRB in placed. The nonlinear static analysis is performed to obtain capacity curve using inverted triangular load pattern as described in ASCE7-10 [2]. The behaviors of investigating frames are discussed and evaluated by means of capacity curves and plastic hinge formation mechanism. Moreover, nonlinear time history analysis is carried out to investigate the effect of BRB properties on the seismic behavior of building model subjected to selected ground motion records. Furthermore, response parameters of building model are presented and compared in the form of base shear, story displacement, and story drift.
A Method of the Lagrange Polynomial Interpolation with Weighting Factors for Reducing Computational Time
Authors: Prasopchingchana Uthai
Published: September 2022

This paper proposes a novel extrapolation method known as the Lagrange polynomial interpolation with weighting factors (LPI-WF) to determine initial guess values in each time step for solving equation systems of transient problems using iterative methods. The LPI-WF method is developed from the Lagrange polynomial interpolation to determine the direct extrapolation values and multiply them with the weighting factors. The weighting factors are calculated by considering the number of the previous time steps involved in the extrapolation and the duration between the present time step and the previous time steps. Thus, the LPI-WF method is proper for use with highorder temporal schemes. The key advantages of the LPI-WF method are that the computational time required to achieve the steady-state condition of the transient problems is reduced and the computation codes with the LPI-WF method is more stable than without the LPI-WF method at high time step values. A performance test of the LPI-WF method is carried out by comparing the computational time based on the “lid-driven cavity flow” problem for Reynolds numbers of 1000 and 5000. The test result shows that the computational time of the problem when the LPI-WF method is adopted can be reduced up to 10.46 % compared to the conventional method.
Electrospinning, Preparation and Characterization of Polyvinylidene Fluoride / Pectin Electrospun Loaded with Benzalkonium Chloride as a Drug Reservoirs
Authors: Anwar Hamzah Mohd Syahir , Ng Celine , Abdul Sukor Jumadi , Mohd Ali Kamarul Syazwan , Mat Nayan Nadirul Hasraf
Published: September 2022

Porous nanofiber electrospun of polyvinylidene fluoride (PVDF)/pectin was successfully developed using electrospinning method containing benzalkonium chloride (BAC) as a drug model for the controlled drug delivery system assessment. The electrospun was tested for its mechanical, morphological, and wettability properties. Scanning electron microscope (SEM) micrograph demonstrated that the smooth surfaces of nanofibers morphology had achieved up to 2 wt% pectin inclusion with optimum fiber diameter, 143 ± 1.4 nm. The optimized scaffold PVDF/Pectin showed that the reduction of mechanical integrity and the optimum value of tensile strength, modulus strength, and elongation at break were 5.98 ± 0.17 MPa, 16.82 ± 0.10 MPa, and 79.3 ± 1.3% MPa. Water contact angle analysis and degree of swelling suggested that the inclusion of pectin had enhanced the wettability properties of hydrophobic PVDF electrospun with the highest swelling capacity achieved of 78.9 ± 1.7%. The in vitro drug release tests using BAC, which was released from the hybrid electrospun nanofibers, achieved prolonged release profile due to the elimination of the uncontrollable initial burst release. Kinetic release study from Higuchi Model and Korsmeyer-Peppas further validates that the drug release mechanism is only influenced by the diffusion factor. The present study indicates the potential of PVDF/pectin electrospun nanofibers to be exploited as a tool for a sustainable drug delivery system.
Design of an Environmental Stress Cracking (ESC) Tester using Fracture Mechanics Approach
Authors: Mohamad Nor Azli Muhamad Syafiq , Mohd Radzi Muhammad Faris , Ahmad Nazri Muhammad Naguib , Saharudin Mohd Shahneel , Inam Fawad
Published: September 2022

In this research, an ESC tester machine was built by utilising a fracture mechanics approach. The machine consists of critical components such as an aluminium frame, 3D printed pulley and bracket, DC motor, Arduino microcontroller, and fasteners. The test was performed by securing an acrylic sample using a hook fixed to bracket on the base of the frame and integrated load cell with Arduino microcontroller board. Digital camera was used to capture images with Image J processing software to measure the transient damage area and macro-crack length development at each test condition. The results suggested that the applied load can influence the fracture toughness values. At 55N, the fracture toughness for the acrylic was 1.9 MPa.m1/2 . Increasing the load to 65N, the fracture toughness dropped by 60% to 0.7 MPa.m1/2. The minimum fracture toughness was observed at 85N load; a 91% reduction was recorded. Maximum damage area of 89 mm2 was recorded for sample tested at 55N while minimum damage area was at 85N load, where only 31.81 mm2 area was calculated. It can be concluded that this newly built machine can be used to perform fracture toughness test on polymeric materials under environmental stress cracking (ESC) condition.
Advantages of Taguchi Method compared to Response Surface Methodology for achieving the Best Surface Finish in Wire Electrical Discharge Machining (WEDM)
Authors: Kandala Ananta Venkata Uday Kiran , Solomon Darius Gnanaraj , Arulraj Joseph Jeyapaul
Published: September 2022

Design of Experiments is a method to predict the optimum conditions of a process to reduce the time and number of experiments to be conducted with limited resources. In this paper, a comparative work on design and analysis of experiments between Taguchi method and response surface methodology is carried out in predicting the set of optimal conditions for obtaining the best surface roughness of commercially pure titanium powder metallurgy component using wire electrical discharge machining process. With surface roughness of the Titanium as the response and pulse on time, pulse off time, and sintering temperature of the wire electrical discharge machining process as the affecting factors, the optimum conditions for the surface roughness of the material have been predicted and analysed. Analysis of variance is used to identify the significant factors affecting the system. Both methods gave the same results and the Taguchi approach requires less number of experiments compared to response surface methodology and the predicted surface roughness of the components with the Taguchi method is 2.4 µm, whereas it is between 2.41-3.04 µm with the Response Surface Methodology. The factor Pulse on Time (N) shows a significant effect on the response of the system.
Il trattato sul sacrificio di Psellos: ieroscopia e influssi astrologici
Authors: Costanza Salvatore
Published: September 2022

Il trattato bizantino attribuito a Michele Psellos e pubblicato da O’ Meara (1989) è una testimonianza di notevole rilievo per il sacrificio e la ieroscopia, data la proibizione della tecnica fondata sull’esame delle viscere a partire dall’età costantiniana e la presumibile scomparsa in età bizantina. Tuttavia, l’indagine de extis è descritta nella Chronographia e nell’Historia Syntomos pselliane, in riferimento a Barda Foca e Costantino V Copronimo. Pare, quindi, opportuna un’attenta riconsiderazione e traduzione dell’opera che mostra notevoli connessioni con altre pseudo-scienze divinatorie del periodo bizantino, con l’astrologia in primo luogo, ma anche con l’omoplatomanzia, le cui predizioni tratte dall’osso della scapola di un animale rappresentano la rielaborazione medievale della splancnomanzia antica.
ÖĞRETİM ELEMANLARININ EĞİTİMDE ÇOKKÜLTÜRLÜLÜK TUTUMLARI
Authors: ERGİN Ayşegül Zeynep , FAZLIOĞLU Yeşim , ERGİN Demirali Yaşar
Published: September 2022

Çalışmanın amacı Eğitim Fakültesi akademisyenlerinin eğitimde çokkültürlülük hakkındaki tutumlarını saptamaktır. Bu genel amaç çerçevesinde bağımsız değişkenler olarak Eğitim Fakültesi akademisyenlerinin tutumlarının bazı demografik özelliklere göre farklılık gösterip göstermediği incelenmiştir.

Çalışma, 2016-2017 bahar yarıyılında Trakya Üniversitesi Eğitim Fakültesinde kadrolu olarak görev yapmakta olan 94 akademisyen ile yürütülmüştür. Veri toplama aracı olarak, Yazıcı, Başol, Toprak (2009) tarafından hazırlanan “Öğretmenlerin Çokkültürlü Eğitim Tutumları Ölçeği” kullanılmıştır. Ölçek 5'li derecelemeli 20 maddeden oluşmaktadır. Bu araştırmada verilerin istatistiksel çözümlenmesinde t testi, varyans analizi ve farkın kaynağını saptamak amacıyla Post hoc analiz için LSD teknikleri kullanılmıştır.

Eğitim fakültesi öğretim elemanlarının araştırmada sorgulanan tüm bağımsız değişkenlerdeki durumları ne olursa olsun, hepsinin eğitimde çokkültürlülük hakkında yüksek düzeyde olumlu tutuma sahip oldukları görülmektedir. Öğretmenleri yetiştirecek olan öğretmenlerin olumlu tutuma sahip olmaları sevindiricidir.
ÖĞRETMENLERİN OKUL İKLİMİNE İLİŞKİN ALGILARI İLE PSİKOLOJİK İYİ OLUŞLARI ARASINDAKİ İLİŞKİNİN İNCELENMESİ
Authors: DOĞAN Ümit , ASLAN Mahire
Published: September 2022

Bu araştırma, öğretmenlerin okul iklimine ilişkin algıları ve psikolojik iyi oluş düzeyleri arasındaki ilişkilerin incelenmesi amaçlacıyla gerçekleştirilmiştir. Araştırmada ilişkisel araştırma modeli kullanılmıştır. Araştırmanın evrenini Sakarya ili merkez ilçelerindeki (Serdivan, Adapazarı, Erenler) ilköğretim ve ortaöğretim okullarında görev yapan 12.765 öğretmen oluşturmuştur. Bu araştırmada seçkisiz örnekleme yöntemlerinden tabakalı örneklem tercih edilmiştir. Araştırma kapsamındaki öğretmenlerden ölçek formunu doldurmayı kabul eden 520 öğretmene uygulama yapılmıştır Bu çalışmada elde edilen veriler değerlendirilirken bağımsız değişkenler üzerinde betimsel istatistiksel hesaplamalar yapılmıştır. Elde edilen bulgulara göre, öğretmenlerin okul iklimi algı düzeylerinin aritmetik ortalamalarının orta düzey olduğu, öğretmenlerin okul iklimine ilişkin algılarının tüm ölçekte ve tüm alt boyutlarda cinsiyet değişkeni bakımından anlamlı farklılık göstermediği, çalıştıkları okul kademesi ve meslik kıdem değişkenleri bakımından istatistiksel olarak anlamlı farklılık gösterdiği sonucuna ulaşılmıştır. Psikolojik iyi oluş algılarının katılıyorum düzeyinde olduğu, psikolojik algılarının cinsiyet değişkeni bakımından istatistiksel olarak anlamlı farklılık göstediği, çalıştıkları okul kademesi ve meslik kıdem değişkenleri bakımından istatistiksel olarak anlamlı farklılık göstermediği sonucuna ulaşılmıştır. Gerçekleştirilen korelasyon analizi neticesinde öğretmenlerin okul ikliminin tüm alt boyutları ile psikolojik iyi oluş algıları arasında orta düzeyde pozitif yönde bir ilişki olduğu okul iklimi algıları ile psikolojik iyi oluş algıları arasında pozitif yönde ve orta düzeyde bir ilişkinin bulunduğu bulgusuna ulaşılmıştır. Çıkan sonuçlara göre de yapılan çıkarımlar ve tartışmalar makalede paylaşılmıştır.
COVID-19 patients with acute pulmonary embolism have a higher mortality risk: systematic review and meta-analysis based on Italian cohorts
Authors: Zuin Marco , Rigatelli Gianluca , Bilato Claudio , Quadretti Laura , Roncon Loris , Zuliani Giovanni
Published: September 2022

Background

Acute pulmonary embolism has been recognized as a frequent complication of COVID-19 infection influencing the clinical course and outcomes of these patients.

Objectives

We performed a systematic review and meta-analysis to evaluate the mortality risk in COVID-19 Italian patients complicated by acute pulmonary embolism in the short-term period.

Methods

The study was performed in accordance with the Preferred Report Items for Systematic Reviews and Meta-analyses guidelines. PubMed-MEDLINE and Scopus databases were systematically searched for articles, published in the English language and enrolling Italian cohorts with confirmed COVID-19 infection from inception through 20 October 2021. Mortality risk data were pooled using the Mantel–Haenszel random effects models with odds ratio as the effect measure with 95% confidence interval. Heterogeneity among studies was assessed using Higgins and Thomson I
2 statistic.

Results

Eight investigations enrolling 1.681 patients (mean age 64.9 years, 1125 males) met the inclusion criteria and were considered for the analysis. A random-effect model showed that acute pulmonary embolism was present in 19.0% of Italian patients with COVID-19 infection. Moreover, these patients were at higher mortality risk compared with those without (odds ratio: 1.76, 95% confidence interval: 1.26–2.47, P = 0.001, I
2 = 0%). Sensitivity analysis confirmed yielded results.

Conclusion

In Italian patients with COVID-19 infection, acute pulmonary embolism was present in about one out of five and significantly associated with a higher mortality risk in the short-term period. The identification of acute pulmonary embolism in these patients remains critical to promptly identify vulnerable populations who would require prioritization in treatment and prevention and close monitoring.
Inflammation and heart failure: a two-sample Mendelian randomization study
Authors: Remmelzwaal Sharon , van Oort Sabine , Handoko M. Louis , van Empel Vanessa , Heymans Stephane R.B. , Beulens Joline W.J.
Published: September 2022

Background

It is hypothesized that inflammation leads to heart failure. Results from observational studies thus far have been inconsistent and it is unclear whether inflammation is causally associated with new-onset heart failure. Mendelian randomization analyses are less prone to biases common in observational studies such as reverse causation and unmeasured confounding. The aim of this study was to investigate the causal relation between various inflammatory biomarkers with risk of new-onset heart failure by using a two-sample Mendelian randomization approach.

Methods

Ten inflammatory biomarkers with available genome-wide association studies (GWAS) among individuals of European ancestry were identified and included C-reactive protein (CRP), immunoglobulin E, tumour necrosis factor (TNF), toll-like receptor 4, interleukin 1 receptor antagonist, interleukin 2 receptor subunit α, interleukin 6 receptor subunit α, interleukin 16, 17 and 18. For the associations between the identified SNPs and heart failure, we used the largest GWAS meta-analysis performed by the Heart Failure Molecular Epidemiology for Therapeutic Targets Consortium with 47 309 participants with heart failure and 930 014 controls. For our main analyses, we used the inverse-variance weighted method.

Results

We included 63 SNPs. CRP, TNF, interleukin 2, 16 and 18 were not associated with heart failure with odds ratios (ORs) of 1.01 [95% confidence interval (95% CI: 0.94–1.09), 1.11 (95% CI: 0.80–1.48), 0.97 (95% CI: 0.93–1.02), 0.99 (95% CI: 0.96–1.03) and 1.01 (95% CI: 0.97–1.06), respectively. The other biomarkers were also not associated with the risk of heart failure and suffered from weak instrument bias.

Conclusion

This Mendelian randomization study could not determine a causal relationship between inflammation and risk of heart failure. However, some biomarkers suffered from weak instrument bias.
Discussion of cost continues to be uncommon in companion animal veterinary practice
Authors: Groves Catherine N. H. , Janke Natasha , Stroyev Alexandra , Tayce Jordan D. , Coe Jason B.
Published: September 2022

OBJECTIVE

To determine the prevalence and nature of cost conversations occurring during veterinarian-client-patient interactions within companion animal practice.

SAMPLES

60 randomly selected, practicing veterinarians working in 55 practices across southern Ontario, Canada, and 909 of their clients, sampled by convenience.

PROCEDURES

A cross-sectional descriptive study including 917 video-recorded appointments. Associations between veterinarian, client, or appointment-level factors and occurrence of a cost conversation were evaluated using multi-level logistic regression.

RESULTS

215 of 917 (23.4%) videos included a discussion of cost between the veterinarian and client. Cost conversations involving veterinarians primarily focused on conveying the price in relation to the time or service being offered (74.0% [159/215]), whereas the benefit to the future health and wellness of the patient was conveyed in 14.4% (31/215) of veterinarians’ cost conversations. Costs were most frequently discussed by veterinarians in relation to diagnostic testing (44.2% [96/215]). The odds of a cost discussion occurring were greater during problem appointments versus wellness (P = .011) or recheck (P = .029) appointments, for feline versus canine patients (P = .037), as appointment duration increased (P < .001), and as a client’s number of visits in the past year decreased (P = .049).

CLINICAL RELEVANCE

Discussing cost of care in veterinary practice continues to be relatively uncommon. Opportunities exist for veterinary professionals to frame their communication of the cost of veterinary care in relation to the benefits offered to the future health and wellbeing of the veterinary patient.
Query Translation Optimization and Mathematical Modeling for English-Chinese Cross-Language Information Retrieval
Authors: Zhao Xia , Song Wanhe , Li Min , Zhang Jianjing
Published: September 2022

The basic theory of the neural network model used in this research is particle swarm optimization, applied to English-Chinese translation retrieval and model optimization. The decoded form obtains the translation task sequence. This topic uses TensorFlow to complete the construction of the translation system. This research solves the typical lack of semantic information in the hierarchical model. The demonstration of examples shows that the neural network model based on particle swarm optimization can significantly improve the quality of machine translation.
Societal perception on environmental and socio-economic implications of Tithonia diversifolia (Hemsl.) A. Gray invasion in an Indo-Burma biodiversity hotspot
Authors: Rai Prabhat Kumar , Vanlalruati
Published: September 2022

Tithonia diversifolia (Hemsl.) A. Gray is an emerging and little studied plant invader in North East India, an Indo-Burma biodiversity hotspot. Identifying the impacts of its invasiveness in terms of both harmful and economically beneficial facets is required for the formulation and implementation of sustainable management options. An environmental and socio-economic implication survey through the pragmatic questionnaire method is a useful approach to explicitly elucidate the holistic influence of T. diversifolia on ecosystem resilience. The interaction of T. diversifolia with the local people of Mizoram was assessed in this study in terms of its effects on their livelihoods, socio-economic, and ecological factors. Results of the survey in relation to agricultural implications revealed that 42.68% of the respondents opined that the dried litter of T. diversifolia can improve soil fertility. Also, 63.41% people during their interview perceived T. diversifolia as an effective tool to prevent. However, 70.73% of rural people did not consider T. diversifolia to be a good source of livelihood for income generation or socio-economic status. Since, the respondents were not aware of chemical and biological control measures to regulate the spread of invasive alien plant species, physical methods such as slashing (46.34%), burning (13.41%), chopping and burning (29.27%) were widely applied for the control and management of invaded areas of T. diversifolia at selected study sites. Thus, the survey gave a brief idea to the other local people, farmers, and agriculturists of Mizoram to control the invasive spread of T. diversifolia in forestry and agroforestry systems. Also, other Himalayan landscapes infested with T. diversifolia can generate awareness and identify the sustainable strategy for their management to conserve the indigenous biodiversity.
Design Build Mini Simulator Navigator Fish Boat (Design and Build Mini Fishing Ship Navigatioan Simulator)
Authors: Saputra Jasnur , Marjoni Marjoni
Published: September 2022

Navigation simulators have a very important role in the learning process to steer the ship's motion safely virtually based on the same shape and function as the original. However, the absence of a navigation simulator at the Aceh Marine and Fisheries Polytechnic of the Capture Fisheries Study Program (PTK) is thought to be the cause of the non-optimal learning process so that a navigation simulator is needed. This study aims to facilitate the navigational science learning process so as to make this navigation simulator a teaching and learning tool in the classroom, both in theory and practice. The method of designing and building a mini fishing boat navigation simulator is carried out in three stages, namely the literature review method, the observation method and the field work method. The results obtained are a navigation simulator with compass, radar, electronic maps, steering, weather control, ship lights and sound signals. The building space for this fishing boat navigation simulator can be used as a learning tool to sail ships and can increase interest in learning.
The Death Ritual of Mosalaki PU'U (Leading Traditional Figure) form Respect to the Ancients of The Wolotopo Traditional Community
Authors: Bego Karolus Charlaes
Published: September 2022

The Indonesian people should be proud of the diverse cultures that we have. That pride must last forever, the Indonesian people must be good at taking care of their culture. Do not expect other people to love and admire our culture, therefore we ourselves must maintain and care for our culture. The implementation of the death ritual of Mosalaki Puu (Traditional Leader Leader) is a form of respect for the ancestors of the Wolotopo indigenous people, which has been inherited from generation to generation. The results of the study found that when Mosalaki Puu (Traditional Leader Leader) died, there were several rituals carried out, namely 1) beating the gong, 2) washing the corpse, 3) bending the corpse's legs and wearing oversized clothes, 4) honoring the corpse, 5) procession of the corpse towards grave pits, and 6) burial of bodies. The meaning contained in some of the rituals of death rituals.
Feed Enriched With Marigold Flower Meal to the Intensity of the Color of Guppies (Poecilia Reticulata)
Authors: Harun *Harun , Thaib Azwar , Nurhayati Nurhayati , Haiqal Muhammad , Suprihadi Suprihadi
Published: September 2022

Guppy fish (Poecillia reticulata) is a type of freshwater ornamental fish that is widely known and is an export commodity. The advantages of guppy fish include having interesting color variations and various fin patterns, easy to maintain and easy to breed. Male guppies have a higher economic value than female guppies. Because male fish have a more attractive shape and color than female fish. In order to increase the economic value of guppy fish, it is necessary to make efforts to increase the color intensity of guppy fish. This study aims to determine the color intensity of guppy fish (Poecilia reticulata) enriched with marigold flower flour. The experimental design used in the study was 2 treatments and 2 replications. Treatment A = Without marigold flower flour and Treatment B = Using marigold flower flour. Parameters observed were fish color measurement, weight growth, survival. The results showed that the addition of marigold flour had a significant effect on color intensity (p 0.05).
Potensi Terjadinya Banjir Rob Akibat Penurunan Muka Tanah dan Kenaikan Muka Air Laut di Kabupaten Badung, Bali
Authors: Elvansha Frans , Hendrawan I Gede , Mandhara Brasika Ida Bagus
Published: September 2022

Badung Regency is one of the tourist areas crowded with visitors, so that development continues to be developed as a support for tourist areas, one of which is a hotel. Hotel construction can cause building loads in a certain period; it can cause land subsidence. Land subsidence that co-occurs with sea-level rise can potentially be a tidal flood in the future. This study aimed to determine the rate of land subsidence in Badung Regency and the potential for tidal flooding due to land subsidence and sea-level rise in Badung Regency. The method used to calculate the rate of land subsidence is Small Baseline Subset Differential Interferometric Synthetic Aperture Radar (SBAS-DInSAR), which utilizes radar satellite imagery data Sentinel-1a IW level 1.1 images and Sentinel-1b IW level 1.1 images. The image data used in the SBAS-DInSAR method consists of 166 image data and Digital Elevation Model (DEM) data with a spatial resolution of 30 m which is used for the topographic phase removal phase. Meanwhile, land subsidence data is used to determine the potential for tidal flooding, and it is predicted using regression; then, an overlay is carried out with the highest tide data along with the value of sea-level rise every year. To facilitate the observation of land subsidence, the daily image data obtained are then averaged into monthly data in each village. The fastest land subsidence rate from 2014 to 2020 occurred in Tuban Village. The prediction of the most significant tidal flood in 2030 to 2040 will occur in Tuban Village due to the influence of rapid land subsidence in the village.
PEMANFAATAN Trichoderma spp. SEBAGAI BIOKONTROL Sclerotium rolfsii Sacc. PADA TANAMAN KEDELAI (Glycine max L.)
Authors: Oktaviawati Candra Dewi , Sudirga Sang Ketut , Hardini Junita
Published: September 2022

Sclerotium rolfsii Sacc. merupakan jamur penyebab penyakit pada tanaman kedelai (Glycine max L.) yang menyebabkan penurunan produksi kedelai. xSalah xsatu xupaya xuntuk xmeningkatkan ketahanan xtanaman kedelai terhadap S. rolfsii adalah dengan menggunakan agen hayati Trichoderma spp. Tujuan dari penelitian inixuntuk menekan infeksi jamur S. rolfsii xpada xtanaman xkedelai menggunakan Trichoderma spp. Metode ppenelitian xmenggunakan xRancangan xAcak xLengkap (xRAL), xdengan 5 xperlakuan xyaitu xa) media tumbuh xtanpa perlakuan (kontrol); xb) media tumbuh + x10 g Trichoderma spp., dan tanpa S. rolfsii; c) media tumbuh tanpa Trichoderma spp., + 5 g S. rolfsii; d) media tumbuh + 15 g Trichoderma spp., dan 5 g S. rolfsii; e) media tumbuh + 20 g Trichoderma spp., dan 5 g S. rolfsii. xPerlakuan xdiulang xsebanyak x5 xkali dan xdiperoleh kombinasi perlakuan sebanyak 25. Data xdianalisis xmenggunakan Analysis xof xVariance (xANOVA), didapatkan xhasil xyang xberbeda xnyata ?<0,05 xdilanjutkan xdengan analisis Post Hoc xDuncan Test. Hasil penelitian secara In Vitro menunjukkan Trichoderma spp. dapat menghambat S. rolfsii sebesar 55,56%, secara In Vivo Trichoderma spp. dapat menghambat S. rolfsii sebesar 40%, dosis optimal Trichoderma spp. sebesar 20 g berdasarkan tingginya rerata berat polong yang dihasilkan, rerata tinggi tanaman tertinggi yaitu 64,4 cm, rerata berat kering tajuk tertinggi sebesar 5,1 g, rerata berat kering akar tertinggi  sebesar 0,5 g, dan rerata berat polong tertinggi sebesar 17,0 g.
(АНТИ)РЕЛІГІЙНА ПОЛІТИКА РАДЯНСЬКОЇ ДЕРЖАВИ НА ЗАКАРПАТТІ В 1953 р.
Authors: ДАНИЛЕЦЬ Юрій , МІЩАНИН Василь
Published: September 2022

Мета дослідження – дослідити релігійну політику радянської влади на Закарпатті стосовно конфесій краю завершального етапу сталінщини та прослідкувати початки активізації антирелігійної кампанії у 1953 р. Розглянути діяльність республіканських та обласних уповноважених (у справах релігійних культів та у справах РПЦ) у втіленні релігійної політики союзного центру, реакцію керівників окремих конфесій на дії влади, (не)сприйняття населенням атеїстичної пропаганди і агітації. Методологія дослідження базується на принципах історизму, системності, науковості, верифікації, авторської об’єктивності, а також на використанні загальнонаукових (аналіз, синтез, узагальнення) і спеціально-історичних (історико-типологічний, історико-системний) методів. Наукова новизна полягає у спробі дослідити один із найскладніших етапів державно-церковних відносин радянського періоду в багатоконфесійному Закарпатті. Висновки. Релігійна ситуація на Закарпатті завершального періоду сталінщини була складною. У 1949 р. у краї радянською державою силовими методами було ліквідовано греко-католицьку церкву – одну з найбільших конфесій краю. Частина греко-католицького священства “возз’єдналася” з православною церквою, частина офіційно перейшла на цивільну роботу, продовжуючи таємно виконувати релігійні обряди. Більше сотні священників було засуджено на тривалі терміни ув’язнення. Розв’язавши питання з греко-католицькою церквою, влада намагається встановити цілковитий контроль над рештою конфесій. Зокрема, найбільшою на цей час стала православна конфесія, яка в 1945 р. вийшла з підпорядкування Сербської православної церкви і перейшла в юрисдикцію Руської православної церкви. Доволі сильні позиції зберігала й римо-католицька церква. Тепер головним завданням комуністичної влади стало “зменшення релігійності населення”. Вже наприкінці 1952 р. на початку 1953 р. влада переходить до активних дій. На обласному, окружному та місцевому рівнях лектори читають сотні лекцій на природничо-наукові й антирелігійні теми, демонструють кінофільми, проводять роз’яснювальні бесіди. В обласній пресі з’являються перші публікації на антирелігійну тематику. Доцільно відзначити, що певні здобутки в антирелігійній роботі все ж були (вихід на роботу під час релігійних свят, стовідсоткова відвідуваність учнями шкіл), проте прогнозованих результатів ця кампанія не досягла. Трансформувати світогляд населення Закарпаття на суцільно атеїстичний більшовикам так і не вдалося.
Associated Factors for the Development of Alcohol Withdrawal Delirium
Authors: Chien Nguyen Huu , Thi Thuy An Le , Viet Chung Nguyen
Published: September 2022

Abstract: This study was conducted to evaluate some associated factors predicting the development of alcohol withdrawal delirium; 56 patients in E hospital were divided into two groups including group 1 of 28 patients diagnosing mental and behavioral disorders due to use of alcohol, withdrawal state with delirium (F10.4) and group 2 of 28 patients diagnosing mental and behavioral disorders due to use of alcohol, withdrawal state (F10.3) according to ICD-10 criteria; Method: cross-sectional study; Result showed that clinical features are sweating and seizure; laboratory tests are GGT, total bilirubin, direct bilirubin, platelet emerged as associated factors of alcohol withdrawal delirium. The level of direct bilirubin over 13 μmol/L is the strongest associated factor with OR(95%CI) 6(1.648-21.840). These risk factors about alcohol dependence featured can be easily evaluated in a clinical setting for physicians to identify patients at risk for developing alcohol withdrawal delirium to make intensive therapy plans for them.

Keywords: Alcohol withdrawal delirium, risk factor, clinical feature, laboratory test.
The Susceptibility to Antibiotics of Isolated Bacteria and the Suitability of Antibiotic Regimens to Drugs Susceptibility Test for Patients with Community-acquired Pneumonia at National Hospital 74
Authors: Trung Tran Thanh , Linh Vu Khanh , Nhat Bui Son , Thi Luyen Le
Published: September 2022

Abstract: Community-acquired pneumonia (CAP) is a common infectious disease in clinical practice. The objective of the study was to describe the susceptibility to antibiotics of isolated bacteria and to analyze the suitability of antibiotics regimens for treatment after having a drugs susceptibility test (DST) to bacteria in CAP patients. A retrospective study was conducted at National Hospital 74, after screening the medical records of CAP patients hospitalized in the first 6 months of 2021, 32 patients with isolated pathogenic bacteria were included in the study. The results revealed that the percentage of CAP patients who isolated pathogenic bacteria was low. There were 9 isolations of isolated bacteria, in addition to the common bacteria in CAP, also including isolations of bacteria that commonly cause hospital-acquired pneumonia such as P. aeruginosa and S. aureus. Different strains were tested with different antibiotics and had different antibiotic susceptibility despite the same isolations of bacteria. Some physicians have not noticed the role of DST results in the choice of antibiotics for treatment, such as treatment regimens are not suitable for the results of DST, accounting for a high percentage.

Keywords: Community-acquired pneumonia, drugs susceptibility test.
Implementation of Labour Commitments in Vietnam’s New Generation Free Trade Agreements and Experience from International Disputes
Authors: Quan Ngo Trong
Published: September 2022

Commitments on labor standards or trade and sustainable development recently emerge in new-generation free trade agreements (FTAs) of Vietnam including the CPTPP or EVFTA. Member states shall enforce their labor laws in a manner that does not interfere with free and fair trade and investment. This article analyzes the tribunals’ decisions in the only two disputes in the world to date arising from violations of labor commitments in FTAs, including disputes of the Dominican Republic - Central America - United States FTA (CAFTA-DR) and the EU-Korea FTA. On the basis of similar commitments of Vietnam, this article draws some lessons for better implementation of its FTAs’ labor commitments.
Improving the Provisions on Enforcement of Intellectual Property Rights in Order to Implement Vietnam’s Commitments in the New-Generation Free Trade Agreements
Authors: Thao Nguyen Bich
Published: September 2022

The Law on amending and supplementing a number of provisions of the Law on Intellectual Property, which was passed by the National Assembly on June 16, 2022, has marked a new development stage of Vietnam’s intellectual property law in the process of international integration with the incorporation of many commitments of Vietnam in the new-generation free trade agreements, including strong commitments on enforcement of intellectual property rights. This article analyzes the formulation and development of international standards on enforcement of intellectual property rights, focusing on the new provisions of new-generation free trade agreements on enforcement of intellectual property rights compared to those under the TRIPS Agreement of the World Trade Organization. From there, the article compares these international standards with the Law on amending and supplementing a number of provisions of the Law on Intellectual Property and makes recommendations to continue improving Vietnamese intellectual property law on enforcement of intellectual property rights.
Epistaksis pada Polip Nasal
Authors: Irfandy Dolly , Wulandari Yunita , Budiman Bestari Jaka , Mayorita Pamelia
Published: September 2022

Pendahuluan: Polip nasal merupakan kondisi multifaktorial yang sering dikaitkan dengan berbagai penyakit dan gangguan patogen, seperti alergi, infeksi, sinusitis jamur alergi, fibrosis kistik, asma, dan intoleransi aspirin. Polip nasal dapat berperilaku agresif dan menirukan patologi lain di rongga hidung dan paranasal. Polip nasal inflammatory type merupakan tipe polip nasal terbanyak kedua dari kasus polip. Bedah sinus endoskopi (BSE) biasanya diperuntukkan bagi pasien yang tidak mendapatkan perbaikan gejala dari tatalaksana medikamentosa, pasien yang memiliki kontraindikasi atau yang mengalami efek samping dari terapi tersebut. Maksilektomi medial menjadi salah satu teknik operasi untuk tatalaksana pada polip nasal. Dilaporkan satu kasus pasien perempuan, 33 tahun dengan keluhan utama riwayat hidung berdarah berulang dan didiagnosis dengan polip nasal inflammatory type yang dilakukan terapi maksilektomi medial. Maksilektomi medial merupakan salah satu teknik pembedahan pada tatalakasana polip nasal.
Potensi Ekstrak Daun Sirsak Dalam Menginduksi Apoptosis Sel Kanker Serviks HeLa
Authors: Putri Nadya Mirenda , Arisanty Dessy , Hilbertina Noza
Published: September 2022

Latar Belakang: Kanker serviks merupakan kanker dengan tingkat kematian tertinggi pada wanita di Indonesia. Sebagian besar penderita kanker serviks datang pada stadium lanjut yang menyebabkan pengobatan menjadi kurang optimal sehingga memerlukan penelitian untuk mencari modalitas terapi, termasuk terapi alternatif. Setiap sel kanker mempunyai karakteristik khusus akibat mutasi genetik (hallmark of cancer) seperti sel kanker serviks yang memiliki kemampuan untuk menghindar dari apoptosis. Pada penelitian terdahulu, ekstrak daun sirsak berpotensi menginduksi apoptosis pada sel kanker. Objektif: Penelitian ini bertujuan untuk mengetahui potensi ekstrak daun sirsak dalam menginduksi apoptosis pada sel kanker serviks HeLa.
Metode: Penelitian in vitro ini dilakukan dengan sel kanker serviks HeLa. Sel HeLa yang konfluens diinkubasi selama 24 jam setelah diberi perlakuan ekstrak daun sirsak dengan konsentrasi IC50 15,8 µg/ml. Apoptosis dilihat dengan pewarnaan Acridine Orange dan Propidium Iodide dan dilihat dibawah mikroskop fluoresens. Analisis data dilakukan menggunakan uji T independen.
Hasil: Persentase apoptosis sel HeLa lebih tinggi pada kelompok perlakuan dibandingkan  kelompok kontrol. (p< 0,001)
Kesimpulan: ekstrak daun sirsak dapat menginduksi apoptosis pada sel HeLa.
Dermatologic care of the lesbian, gay, bisexual and transgender community of India
Authors: Ravindran Surya , Nazeer Mohamed , Criton Sebastian
Published: September 2022

Background

In the Indian subcontinent, the lesbian, gay, bisexual, transgender, and queer community, commonly referred to as the third gender or transgender, is expected to exceed one million by 2030. Data on dermatologic conditions of the transgender population is deficient.

Aims

This study aimed to identify the common dermatological concerns and dermatologic procedures of the lesbian, gay, bisexual, transgender, and queer community of India.

Methods

This cross-sectional survey analysed the transgender participants of a non-institutionalised population in India via health camps that included 51 adult participants who self-identified as trans men and trans women.

Results

This study included 51 participants aged 20-49 years, of which the majority (94%) were trans women. The common dermatological problems were terminal hairs over the face, beard distribution, androgenetic alopecia, scars of gender-affirming surgeries, facial melanosis with topical steroid damaged skin and the need for facial feminisation procedures among trans women, while trans men had testosterone-related acne, androgenetic alopecia. Overall, 40.6% of participants reported dissatisfaction with one or more of their body parts. Laser hair removal was the most common gender-affirming dermatologic procedure.

Conclusion

This study provides an essential overview of the common dermatological conditions and procedures in the Indian lesbian, gay, bisexual, transgender, and queer community. Lesbian, gay, bisexual, transgender, and queer persons have insufficient access to dermatological services due to inadequate exposure and fear of discrimination. Even though transgender patients also present with similar dermatologic conditions as the general population, they have distinct cosmetic and treatment concerns during the period of transition owing to hormone-related or surgery-related changes. Addressing these challenges through enhancing dermatology residency training programs should be the focus of tomorrow.

Limitations

Considering convenience sampling and representative bias, further studies need to be conducted involving multiple study locations and larger sample sizes.
ИССЛЕДОВАНИЕ ВИТАМИННОГО СОСТАВА РАСТОРОПШИ ПЯТНИСТОЙ
Authors: Клейменова Наталья Леонидовна , Кашолкина Дарья Андреевна , Болгова Мария Анатольевна , Копылов Максим Васильевич , Болгова Инэсса Николаевна
Published: September 2022

Предметом исследования данной научной статьи являются семена расторопши пятнистой. Расторопша – известное лекарственное растение, богатое ценными биологически активными веществами, макро и микроэлементами, витаминами. Расторопша относится к нутрицевтикам, исследование состава семян растения имеет практическое значение для создания масел функциональной ценности для удовлетворения физиологической потребности человека в необходимых для организма полезных веществах. Проведено исследование витаминного состава расторопши пятнистой в соответствии со стандартными, а также на состав минеральных элементов. В ходе экспериментальных исследований в семенах расторопши пятнистой установлено присутствие β-Каротина, витамина В1, витамина В2, витамина В4 и витамина Е. Самое высокое содержание имеет холин (В4). Присутствие α-токоферола, или витамин Е, предотвращает окисление липидов организма, включая полиненасыщенные жирные кислоты и липидные компоненты клеток и мембранные органеллы. Также было установлено, что семена масличной культуры содержат железо, цинк, марганец, йод, селен, медь, хром, калий, кальций, магний, фосфор. Содержание железа, цинка преобладает среди микроэлементов, количество фосфора и кальция среди макроэлементов. Семена являются потенциальным источником масла, которое можно использовать в качестве функциональных пищевых и диетических добавок. Масло, полученное из семян расторопши, может быть интересным функциональным компонентом пищи, но необходим подробный анализ, чтобы подтвердить его применимость и влияние на здоровье человека. Масло семян расторопши холодного отжима имеет лучшее качество и может рассматриваться как ценный источник новых многоцелевых продуктов или побочных продуктов для промышленного, косметического и фармацевтического использования.
Of shadows and gaps in spatial search
Authors: Chan Ada , Godsil Chris , Tamon Christino , Xie Weichen
Published: September 2022

Spatial search occurs in a connected graph if a continuous-time quantum walk on the adjacency matrix of the graph, suitably scaled, plus a rank-one perturbation induced by any vertex will unitarily map the principal eigenvector of the graph to the characteristic vector of the vertex. This phenomenon is a natural continuous-time analogue of Grover search. The spatial search is said to be optimal if it occurs with constant fidelity and in time inversely proportional to the shadow of the target vertex on the principal eigenvector. Extending a result of Chakraborty \etal ({\em Physical Review A}, {\bf 102}:032214, 2020), we prove a simpler characterization of optimal spatial search. Based on this characterization, we observe that some families of distance-regular graphs, such as Hamming and Grassmann graphs, have optimal spatial search. We also show a matching lower bound on time for spatial search with constant fidelity, which extends a bound due to Farhi and Gutmann for perfect fidelity. Our elementary proofs employ standard tools, such as Weyl inequalities and Cauchy determinant formula.
Correcting pi-delocalization errors in conformational energies using density-corrected DFT, with application to crystal polymorphs
Authors: Rana Bhaskar , Beran Gregory , Herbert John
Published: September 2022

We consider several molecules characterized by pi-electron conjugation whose extent changes along a flexible torsional coordinate, and which represent the monomer units of polymorphic molecular crystals. Delocalization error in density functional theory (DFT) adversely impacts conformational energies in these species, overstabilizing the conformation that maximizes conjugation length and leading to incorrect relative energies for the corresponding crystal polymorphs. We demonstrate that density-corrected (DC-)DFT, in which a DFT exchange-correlation functional is evaluated using a Hartree-Fock density, significantly reduces these conformational energy errors. When DC-DFT monomer energies are used as a low-cost intramolecular correction to a periodic DFT calculation of the molecular crystal, the resulting relative polymorph energies are within 1 kJ/mol of benchmark results.
Serum ferritin level and B12 in a sample of Iraqi re-current aphthous stomatitis patients
Authors: Ali Noor S
Published: September 2022

Background: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal disorders with a prevalence of 50-66%. The prevalence of hematinic deficiencies including ferritin and vitamin B12 deficiencies and their role in the prophylaxis and development of RAS is not well known. Many studies have demonstrated a high prevalence of hematinic deficiencies in patients with RAS. This study aimed to compare the serum level of ferritin and vitamin B12 in patients with recurrent aphthous ulcers and healthy controls. Subjects, Materials and Methods: The data were collected from patients who needed blood analysis to exclude anemia from November 2020 to May 2021. The study was approved by the institutional ethics committee. After recording patients' demographics ( age, gender, occupation, address)  5ml of blood was drawn from patients and controls in educational laboratories centrifuged at 3000 rpm for 10 minutes, then serum was stored at -20°C till the time of assessment of both serum ferritin and vitamin B12. The data were expressed as Mean ± SD. Students Unpaired t-test was used for comparing biochemical parameters between patients and controls and a p-value of <0.05 was considered as a statistically significant while a p-value of<0.001 was considered highly statistically significant. Results: A total of 30 RAS patients and 30 healthy control with age and gender matches were included. In the present study statistically, significant differences were observed in the serum level of ferritin and vitamin B12 between the two groups, 40% of the patients had low serum ferritin levels and 56.6 % of the patients had low serum vitamin B12 levels. Conclusion: Measuring serum ferritin and vitamin B12 levels are necessary for patients with recurrent aphthous stomatitis. It is also important for recurrent aphthous ulcer patients to have a nutritional diet containing iron and vitamin B12 to prevent the recurrence of aphthous ulceration