bluuebunny/crossref_metadata_2025 huggingface dataset:
Upaya Meningkatkan Hasil Belajar IPA Siswa dengan Menggunakan Metode Demonstrasi pada Kelas VI SD Negeri 01 Durian Tinggi Kecamatan Kapur IX Kabupaten Lima Puluh Kota
Authors: Arlis Arlis
Published: November 2019

This study aims to improve student learning outcomes in class VI State Elementary School 01 Durian Tinggi, because so far classical learning models have not been able to improve student learning outcomes. Data collection is carried out by observation, tests, and observation sheets. The results of the observations are then analyzed and made as an action planning material in the next cycle and then processed in order to draw conclusions. Based on preliminary observations, the initial data obtained about student learning outcomes is that 4 people get very good grades, 7 people get good grades, 20 people get pretty good grades and 1 person gets bad grades. Then the average grade obtained is 73.125. After being implemented in the first cycle, 10 people got very good grades, 15 people got good grades, 6 people got good grades and 1 person got bad grades. The average score of students in cycle I was 78.75. And after implementing the second cycle, 12 people get very good grades, 21 people get good grades, and no one gets good enough grades and less grades. The average score of students in cycle II is 83.98. Based on the results above we can conclude that student learning outcomes have experienced a very good improvement.Implications of the results of Classroom Action Research (CAR) by using the Demonstration method can improve the students’ learning outcomes and also have a positive effect on the activities of class VI students of SDN 01 Durian Tinggi.
Pengaruh Motivasi dan Stres Kerja terhadap Kinerja Karyawan pada Bank Nagari Cabang Syari’ah Payakumbuh
Authors: Rahmawaty Dian
Published: November 2019

This study aims to determine the effect of motivation and work stres on the performance of employees of Bank Nagari Branch of Payakumbuh Syari'ah. In connection with the research objectives above, it is hypothesized that "alleged motivation and work stres have a significant partial and simultaneous effect on employee performance". To conduct discussions and research, the author uses primary data directly obtained from the object of research through a list of statements or structured questionnaires that have been answered by employees, and the population of this study is Bank Nagari Employees of Payakumbuh Syari'ah Branch totaling 30 with a sample of 30 people who are determined by the Census (Total Sampling) method. Data processing using SPSS 16.0 help method. The analytical tool used was Binary Logistic Regression Analysis and Hypothesis Test namely G Test, Wald Test, and Exp (B) Test. The results of Binary Logistics Regression analysis obtained the following Equations; Y = -48.994 + 1.819X1 - 0.58X2 shows that motivation has a positive and significant effect on employee performance and job stres has a negative and significant effect on the performance of employees of Bank Nagari Payakumbuh Syari'ah Branch. The motivation variable has the Exp (B) value greater than the other variables, which is 6,163. This shows that the motivation variable has the greatest contribution in improving the performance of Bank Nagari employees at the Payakumbuh Syari'ah Branch.
Peningkatan Hasil Belajar Melalui Penggunaan Metode Diskusi di Kelas V Semester II SDN 03 Talang Maua Kecamatan Mungka
Authors: Ewidarti Ewidarti
Published: November 2019

This research was motivated by the low learning outcomes of the students of SDN 03 Talang Maua. Among the contributing factors is the inappropriate delivery of material and inappropriate methods so that students are bored and not interested in this learning. Other consequences students are not brave and lazy when completing tasks and learning outcomes are low. One of the right ways is to use the Discussion method. The purpose of this study is to improve student learning outcomes in science learning through the use of discussion methods in class V semester II SDN 03 Talang Maua. This type of research is Classroom Action Research (CAR). The subjects of this study were students of class V SDN 03 Talang Maua.
Based on the results of the study showed that the average learning outcomes in the first cycle was 63.47% and the average learning outcomes in the second cycle was 74.13%. This means that the learning outcomes of Natural Sciences through the use of the discussion method at SDN 03 Talang Maua increased compared to the learning outcomes of Cycle 1 with cycle 2.
Peningkatan Hasil Pembelajaran Sains melalui Permainan Tabung Teka-teki pada Kelompok B2 di Taman Kanak-kanak Negeri Pembina Lima Puluh Kota
Authors: Yusni Deli
Published: November 2019

This research was motivated by a lack of interest in Group B2 children in TK Negeri Pembina Lima Puluh Kota Kecamatan Harau in participating science learning about the five senses so that there was a need for improvement. The purpose of this Classroom Action Research is to describe the improvement in the results of science learning about the five senses in the TK Negeri Pembina Lima Puluh Kota. The type of the research carried out was classroom action research with the subject of research of students in the TK Negeri Pembina Lima Puluh Kota in Group B2, which were consisted of 15 pupils using the Puzzle Tube Educational Tool. The technique used in collecting data in the form of observation, and the format of the results of interviews, test, then processed by percentage techniques. This classroom action research was conducted in two cycles. The results of the study in the first cycle of improvement in learning outcomes have not reached 75%, then continued in the second cycle where the increase in children's learning outcomes becomes more increasing. So the results of the average rate of children exceed the minimum completeness criteria that have been set. Thus it can be concluded that the efforts of researchers to improve children's learning outcomes in learning science about the senses. After the actions taken from cycle I and cycle II can be achieved.
Upaya Meningkatkan Hasil Belajar Ekonomi Melalui Pendekatan Saintifik Dengan Model Discovery Learning Metode Diskusi Kelompok Pada Kelas XII IPS 3 Semester Genap Tahun Pelajaran 2017/2018
Authors: Marshusi Marshusi
Published: November 2019

The purpose of writing this class action research is to find out whether the application of learning with a scientific approach accompanied by the Discovery Learning model can improve students' economic learning outcomes. The method of data collection is observation and the results of student learning tests. The data analysis method is descriptive both for qualitative data and quantitative data. The results obtained from this study are the application of a learning model with a scientific approach accompanied by a Discovery Learning model to improve the learning outcomes of economic learners. This proves that the average learning outcomes of knowledge in Cycle I 81.29 rose to 85.33 in cycle II. For the realm of skills students in the first cycle with a percentage of 83.81%, increased to a percentage of 86.03%, while the domain of religious attitudes of students in the first cycle of 88.25 rose to 91.43 and the spiritual attitude in the first cycle was 86.35%. up to 87.94%. The conclusion that can be obtained from this study is the application of learning with a scientific approach along with the Discovery Learning model can improve the economic learning outcomes of students.
Editorial
Authors: Sub\urban Redaktion
Published: November 2019

Liebe Leser_innen,in dieser thematisch offenen Ausgabe von  sub\urban sind eine Reihe von Diskussionssträngen miteinander verflochten, die den Austausch zu Inhalten und Zielen einer kritischen Stadtforschung weiterführen. [...]
Neglect syndrome after ischemic stroke: diagnosis, treatment
options
Authors: Nasonova Tetiana , Kolosova Tetiana , Briakin Danylo , Mykhailovska Natalia , Kurochkin Igor , Riabychenko Tetiana , Tyshkevych Olena , Buhaiov Yurii , Holovchenko Yurii , Hushcha Valeriia
Published: November 2019

The purpose of the study: the study of clinical efficacy and safety
of the Neuromidin® in the rehabilitation period in patients with primary
ischemic stroke, its eff ect on motor, cognitive function, level of household adaptation, depending on the presence or absence of neglekt syndrome and "push-syndrome". 60 patients aged 49 to 82 years in the recovery period of ischemic stroke were examined (30 patients — the main group: treatment with the addition of Neuromidin®; 30 patients — control group: standard treatment without adding Neuromidin®). Investigation of motor, cognitive, and sensitive disorders
was carried out with the use of clinical scales. The effectiveness
of the treatment was evaluated in the absence of signs of neglekt syndrome and "push-syndrome", reduction of motor and cognitive impairment. Patients with neglekt syndrome showed greater
dependence on third-party care and more severe cognitive impairment than in patients who had not been diagnosed neglekt syndrome. After treatment, the majori ty of patients achieved elimination of neglekt syndrome, but in the group where patients received Neuromidin®, the number of such patients was higher. In addition, patients in the main group improved cognitive function. The use of Neuromidin®
in complex rehabilitation measures in patients with ischemic stroke contributes to the restoration of lost functions, reduces the phenomena
of visual-spatial neglect, positively affects self-care and improves the quality of life of patients and their relatives.
Possibilities of optimizing approaches to the treatment of resistant epilepsy in children using pharmacogenetic studies data
Authors: Tantsura Lyudmyla , Pylypets Olena , Tantsura Yevhen , Tretiakov Dmytro
Published: November 2019

We conducted an observation of 83 children with therapy-resistant forms of epilepsy between the ages of 11 months and 18 years. The presence of CYP2C9, CYP2C19 and CYP3A4 gene polymorphisms was detected in 60 of the examined patients, that is, 72.29 % of them, 33 patients (39.76 %) had CYP2C19 gene polymorphisms, CYP2C9 gene polymorphisms had 17 (20.48 %) children, and 10 (12.05 %) of them had CYP3A4 gene polymorphisms. The frequency of CYP2C19*2 and CYP3A4*1B polymorphisms was signifi cantly higher than in the Ukrainian and other European populations, no statistical data signifi - cance of differences in the frequency of CYP2C9 gene polymorphisms compared with the Ukrainian population was found. CYP2C19 gene polymorphisms are signifi cantly more frequently recorded by us compared to the results obtained by researchers in Russia and Turkey in closely related studies. It is shown that children with cytochrome P450 gene polymorphisms are recommended: more frequent clinical, instrumental, and laboratory monitoring of patients to prevent side eff ects of therapy; monitoring (not a one-time study) of AED concentration in blood plasma. The necessity of conduction of pharmacogenetic research at the stage of debut of epilepsy in the case of suspicion of treatment-resistant form of the disease and in the case of ineffi - ciency or severe side eff ects of the fi rst assigned AED was demonstrated. Key words: children, treatment, resistant epilepsy, cytochrome P450, gene polymorphism.
Analysis of medical aid in patients with Duchenne muscular
dystrophy, seven years’ dynamics
Authors: Shatillo Andrii , Fedorenko Hanna
Published: November 2019

The article represents analysis of current practice of medical aid in Duchenne muscular dystrophy (DMD) patients in Ukraine through its compliance to international consensus. DMD is disease, which is related to type of rare ones, it has fatal course and leads to death at the age about twenty years. However, recent abilities of medical management substantially increase periods of good functioning and entire life expectancy. Analysis has been made on data from Ukrainian DMD registry. 75 entries from the registry were selected on basis of data completeness and consistency. Improvements of corticosteroid therapy prevalence and age of diagnosis, compared to 2012 indexes, have been revealed. Most diffi cult problem, which does not have visible progress, is equipment (motorized chairs, cough assist machines, BIBAP-machines) supply. It is noticed that along with widening of specific to DMD children medical aid, number of wrong or inadequate recommendations has been increased. Possibility of medical aid improvement for patients with DMD or similar rare conditions by the help of “centers of expertize” has been discussed.
Keywords: Duchenne muscular dystrophy, DMD, Ukrainian DMD registry, medical management, analisys
Prognostic indicators of the lack of a great functional improvement
and sustained disability among in-patients with
cerebral stroke who were managed in a Comprehensive
Stroke Unit
Authors: Flomin Yuriy
Published: November 2019

High-quality care may help reduce the severity of stroke consequences,
but the optimal model of in-patient cerebral stroke care is not yet defi ned. The aim of the study was to determine the predictors of failing to achieve favorable functional outcome assessed with the Barthel index (BI) after treatment in the Comprehensive Stroke Unit (CSU). Patients with cerebral stroke, who were in 2010 to 2018 admitted to the Stroke Center — a multidisciplinary hospital unit that operates according to the
CSU principles — were enrolled to the study. Patients’ data were prospectively entered into a special database and included baseline and fi nal assessments with neurological scales. If the BI total at discharge exceeded 60 or increased at least by 50 compared with baseline,
the favorable outcome was considered achieved, otherwise — failed.
Among 677 included in-patients, age 20 to 95 years, 271 (40.4 %) females,
80.8 % had an ischemic, and 19.2 % hemorrhagic cerebral stroke.
The median NIHSS score at was 10. The onset to CSU hospitalization
delay ranged from less 24 hours (17.5 % of the patients) to more than
180 days (17.2 % of the patients), and 59.7 % of the participants were admitted during the fi rst 30 days from the index stroke. In multivariate analysis, 7 indicators were strongly and independently linked with the risk for unfavourable functional outcome. The area under the operating characteristics curve (AUC = 0.93) indicates excellent consistency
of the prediction model and the strong association of the predictors
with the risk for a signifi cant need in help in ADLs. Independent predictors of functional insolvency can help better estimate
the prognosis and optimize decision making on treatment strategy.
Patient’s age, recurrent stroke, severity of the initial impairments and
long delay to CSU admission has the most signifi cant infl uence on the risk for disability after discharge from CSU.
Clinical and psychopathological peculiarities of suicidal behavior of people who are ill with schizophrenia living in the zone of the Joint Force Operation
Authors: Budonnyi Pavlo
Published: November 2019

The relevance and the clinical and social need for this study is due to the fact that, to date, no comprehensive treatment and prevention of suicidal behavior has been developed for patients suff ering from schizophrenia from the zone of the Joint Force Operation (JFO). The aim of our study was to identify the clinical and psychopathological features of suicidal behavior of persons suff ering from schizophrenia and living in the OUF zone. In the process of research, a complex of methods was used: theoretical, socio-demographic, follow-up, clinical-anamnestic, clinicalpsychopathological, psychodiagnostic, statistical (calculations were made using Excel MS Offi ce 2016). Taking into account the principles of bioethics and deontology, in the course of the work, 136 people, aged 22 to 50 years, suffering from schizophrenia (according to IDU-10, code F2 "Schizophrenia, schizotypical states and delusional disorders"), were selected and they all have a tendency to suicidal behavior. All studied were divided into two groups: 71 people with a diagnosis of schizophrenia and suicidal behavior, with whom the author’s complex therapy was subsequently carried out — MG (main group); 65 people, also diagnosed with schizophrenia and suicidal behavior, with whom further therapy was carried out according to standard clinical protocols — CG (comparison group). In the future, each group was divided into subgroups by gender: 38 men included in MG1, 33 women and MG2, respectively, 34 men in CG1, and 31 women in CG2. According to the results of the study, the clinical and psychopathological features of suicidal behavior of persons suff ering from schizophrenia and li ving in the JFO zone were determined. The data obtained in this study later became for us markers for the development and implementation of the author’s methodology of medicalpsychological support.
Structure and types of response to disease and indexes of adaptability/maladaptation in endogenous psychoses with episodic course in the context of pathopersonalogical transformations in post-manifestation period
Authors: Khomitskyi Mykola
Published: November 2019

The study examined the structure and types of attitude toward the disease (ATD) and adaptability/maladaptation indices in 312 patients with endogenous episodic episodes (schizophrenia, schizoaff ective disorder (SAD) and aff ective disorders (AD)) in remission/ intermittent states and compared them. Characteristics of ATD and indicators of adaptability/disadaptation in endogenous psychosis with episodic course in the remission/intermission period are a sign of stable post-manifestation of pathopersonalogical transformations and have nosospecifi c diff erences. Patients suffering from endogenous episodic psychosis have a reserve of personal adaptive capacity. This is confirmed by the fact that among patients with maladaptive types of ATD, a signifi cant percentage is of the types with an interpsychic orientation (74.0 % of the contingent in AD, 55.9 % of those surveyed with SAD and 57.6 % with schizophrenia), which is a sign of the use of personal reserves in confronting the negative eff ects of the disease. The above-mentioned reserve of personal adaptation possibilities in AD is the largest, as shown by the larger (χ2 = 6.065, p < 0.05) percentages of types with an interpsychic orientation in the structure of maladaptive types of ATD. The obtained data can be implemented into the system of diff erential diagnosis and counteraction to social maladaptation, which is formed as a result of the disease. Key words: schizophrenia, schizoaff ective disorder, aff ective disorders, clinic, adaptation, pathopersonalogical features
RAPID DETERMINATION OF THE IMMOBILIZATION CONDITIONS FOR LEAD AND CADMIUM IN SOIL USING 2, 4, 6-TRIMERCAPTOTRIAZINE, TRISODIUM SALT, NONAHYDRATE
Authors: Jiang Ke , Zhou Kanggen , Zhang Jiangsheng
Published: November 2019

Chemical immobilization is widely used for remediation of heavy metal contaminated soils. The present study proposed a method for the immobilization of lead (Pb) and cadmium (Cd) in soil using 2, 4, 6-trimercaptotriazine, trisodium salt, nonahydrate (TMT). Simulation tests were performed in an aqueous solution to rapidly screen the operational conditions. The effects of TMT dosage, reaction pH, and the coordination ions (Al3+, Fe3+) on immobilization, and the thermodynamics for the TMT-DTPA-Zn-Pb-H2O system, were investigated. The results showed that the immobilization efficiencies of Pb and Cd were removed effectively via the addition of TMT and Fe3+ in the solution containing DTPA. Pb and Cd concentrations decreased from 50 mg/L to <3.9 mg/L and 1.4 mg/L, with a Fe3+/DTPA molar ratio of 0.8 to 2.1, and a TMT dosage of 1.0 mol/mol (Pb and Cd). The screened results in the aqueous solution were used to immobilize Pb and Cd in soil. The extractable concentrations of Pb and Cd in the immobilized soil decreased to 19.6 mg/kg and 1.7 mg/kg, respectively, with a TMT dosage of 2.2 mol/mol (Pb and Cd), and a Fe3+/DTPA molar ratio of 3.6. The bioavailability of Pb and Cd met the environmental quality standard for drylands in China (GB 15618-1995). The results demonstrated that remediation conditions could be rapidly screened in an aqueous solution rather than soil. The method using TMT and ferric sulfate was potentially effective in immobilizing Pb and Cd.
Low Vitamin D is associated with Coronary Atherosclerosis in Women with HIV
Authors: Cheru Lediya T , Saylor Charles F , Fitch Kathleen V , Looby Sara E , Lu Michael , Hoffmann Udo , Stanley Takara L , Lo Janet
Published: November 2019

Background

Vitamin D deficiency is underdiagnosed and undertreated, especially among people living with HIV (PLWH). Recently, there has been an increased interest in the role of vitamin D in cardiovascular disease (CVD). While vitamin D deficiency has been associated with CVD in observational studies in the general population, there are limited data in PLWH. We therefore performed an analysis to assess the relationship of vitamin D and coronary atherosclerosis using coronary CT angiography (CCTA).

Methods

Women living with HIV (WLWH) without known CVD were included. Based on the median value of serum vitamin D levels, participants were dichotomized to either the <25 ng/ml (lower vitamin D group) or ≥25 ng/ml (higher vitamin D group). CCTA was used to assess plaque characteristics.

Results

Forty-three WLWH were included in the analyses (mean age 46 ±8 years, 56% African American, duration of HIV 15 ±6 years, 83% undetectable HIV viral load). WLWH in the lower vitamin D group ( n=22) had significantly higher numbers of segments with any coronary plaque (2.27 ±3.01 versus 0.38 ±0.97; P=0.02) and segments with non-calcified coronary plaque (1.41 ±1.82 versus 0.29 ±0.64; P=0.03) compared with WLWH in the higher vitamin D group ( n=21). After adjusting for Framingham CHD risk point score, body mass index, diabetes and race, the relationship remained significant.

Conclusions

Our study demonstrates a significant, independent relationship between lower vitamin D status and higher numbers of noncalcified coronary plaque segments in WLWH. Further studies are warranted to evaluate the effect of vitamin D on CVD in PLWH. Trial Registration Identifier: NCT00455793.
Herlyn Werner Wunderlich Syndrome with Hematocolpos Symptom
Authors: Rusda Muhammad , Umara Amru , Rambe Andrina Yunita Murni
Published: November 2019

BACKGROUND: Uterodidelphys with obstructed hemivagina and ipsilateral renal agenesis is referred to as the Herlyn Werner Wunderlich (HWW) syndrome. Herlyn-Werner-Wunderlich (HWW) syndrome is a very rare congenital anomaly of the urogenital tract involving Müllerian ducts and Wolffian structures, and it is Werner by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis.
CASE REPORT: Here, we describe a 17-year-old female patient presented with severe and increasing cyclical abdominal pain. She attained menarche 3 years back. The patient had irregular and scanty menstruation associated with dysmenorrhoea. On physical examination, secondary sexual characters were well developed, and on palpation, lower abdomen tenderness was not present. Diagnosed with HWW syndrome, who was taken up for diagnostic sonography and MRI, followed by vaginal septal resection,
CONCLUSION: In addition to a definitive diagnosis, this approach helped in symptomatic relief to the patient.
Decrease Anxiety among Students Who Will Do the Objective Structured Clinical Examination with Deep Breathing Relaxation Technique
Authors: Ariga Reni Asmara
Published: November 2019

BACKGROUND: The anxiety is an emotional and subjective experience without any specific object so that people feel a feeling of worry as if something bad will happen and generally accompanied by autonomic symptoms lasting some time. Like students who will carry out the OSCE exam at the end of each semester as a form of evaluation of the extent to which nursing students have mastered the learning outcomes that have been set during the OSCE examination during the OSCE examination all students are required to display cognitive, affective and psychomotor skills quickly, precisely complete. This is what generally can cause anxiety in students.
AIM: We aimed to determine the decrease in student anxiety about the OSCE exam by relaxing deep breathing.
MATERIAL AND METHODS: This study was a quasi-experiment; pre-post test with control group design. The 40 undergraduate nursing program students with random sampling were divided into two, namely the control group and the intervention group. The instrument uses a questionnaire.
RESULTS: The independent t-test test results with a value of t count 3.743 with a value of p = 0.031 < 0.05, which that there was a decrease in student anxiety about the OSCE exam with deep breath relaxation.
CONCLUSION: It is expected that all students who will carry out the exam can apply this technique to carry out the exam in calm conditions and satisfying results.
Post-Dissociative Trance Disorder: Traditional Culture of Nini Pagar from Tigabinanga
Authors: Ginting Silvana R. R. , Effendy Elmeida
Published: November 2019

BACKGROUND: Dissociative Trance Disorder is uncommon, particularly in the eastern part of the world. Complexity and uniqueness of the symptoms, triggers, as well as the management strategy of this disease, make it an exceptional burden for the family.
CASE REPORT: We reported a 17-year-old woman of a Karo descent who was admitted to Tiga Binanga Primary Health Center by her family due to frequent depressive mood, secluding herself, loss of interest, and frequent fatigue. The complaints persisted for about three weeks. The patient had a confirmed history of dissociative trance disorder known as trance or kesurupan in the local language. This condition is often linked to the local cultural tradition of Nini Pagar performed by the patient. There was neither a history of delusional thoughts, illusions, nor hallucinations. However, the eidetic image was evident.
CONCLUSION: Nini Pagar, in this case, induces trans dissociative disorder and feature of this post dissociative trance disorder is moderate depression. We found that the eidetic image with sensorium is clear (compos mentis). Psychotherapy and pharmacotherapy were helping.
The Comparison of Hospital Anxiety and Depression Scale-Anxiety Scores between Female Caregivers of People with Schizophrenia According to Gender Difference
Authors: Handi Andrew , Gultom Dapot Parulian , Husada Muhammad Surya , Loebis Bahagia , Effendy Elmeida , Amin Mustafa Mahmud , Camellia Vita , Nasution Nazli Mahdinasari
Published: November 2019

BACKGROUND: Caregiver plays an important role for a better outcome in people with schizophrenia, although it usually causes emotional distress for the caregiver. Anxiety is one of the emotional distress. Gender of schizophrenic patients is associated with the emotional distress of caregiver. The differences in HADS-A scores between female caregivers of people with schizophrenia according to gender in Indonesia remain unclear.
AIM: To determine whether HADS-A scores are higher in a male group compare with the female group.
METHODS: This study was an analytical study with a cross-sectional approach to determine the comparison of HADS-A score between 27 female caregivers of male schizophrenic patients (male group) and 27 female caregivers of female schizophrenic patients (female group) in Prof. Dr M. Ildrem Mental Hospital Medan, using a HADS rating scale.
RESULTS: There is no difference between the male and female group in caregivers: age, marital status, employment status, family income/month, education time, the relationship with people with schizophrenia, caring time, time spent / weeks, and the patients age, employment status, education time, PANSS score and number of relapses. The comparison between total HADS-A score between the male group and the female group is not significant with 9.52 ± 4.90 v 8.70 ± 4.49 (p = 0.53).
CONCLUSION: HADS-A scores are not higher in caregivers of male with schizophrenia compared with caregivers of a female with schizophrenia.
Relationship between Internet Gaming Disorder with Depressive Syndrome and Dopamine Transporter Condition in Online Games Player
Authors: Ariatama Bayu , Effendy Elmeida , Amin Mustafa M.
Published: November 2019

BACKGROUND: Internet game playing is experiencing rapid growth in both youth and adult populations. The excess playing this game cause negative consequences, including game addiction. Internet Gaming Disorder is an increasingly prevalent disorder, which can have severe consequences in affected young people and their life.
AIM: To observe the depressive syndrome and dopamine transporter condition (DAT) to find out the severity of internet gaming disorder.
METHODS: To analyse the relationship between IGD and Depressive Syndrome and to analyse the relationship between IGD and DAT in online games player by using Spearman Rank Correlation Analysis. Depression testing is done by using the Patient Health Questionnaire-9 method (PHQ-9). The sample of the experiments of this research was 48 online games players in the internet cafe at Medan Area sub-district, which ages between 20 – 40 years old and have been playing games for at least 12 months
RESULTS: It was found that there was strong one-way relation (0.625) between IGD and PHQ-9 significantly (p < 0.01), however, it was found that strong enough (-0.465) relation between IGD and DAT (p < 0.01) and strong opposite relation (-0.680) between PHQ-9 and DAT (p < 0.01).
CONCLUSION: There was a relationship between Internet Gaming Disorder (IGD) with depressive symptoms and Dopamine Transporter (DAT) level. PHQ-9 score was higher in people with a higher score of IGDS9-SF. As well as DAT level, there was opposite strong enough correlation between IGD and DAT that indicating the higher IGD score, the lower DAT level.
Shared Psychotic Disorder (Folie À Deux): A Rare Case with Dissociative Trance Disorder That Can Be Induced
Authors: Saragih Munawir , Amin Mustafa Mahmud , Husada Muhammad Surya
Published: November 2019

BACKGROUND: Shared psychotic disorder was first introduced in the 19th century in France with the name Folie à deux. Since then, the concept of Folie à deux has been developed and produces several subtypes in France. In DSM, this disorder is called Shared Psychotic Disorder, and in ICD-10, it is called Induced Delusional Disorder. However, some of the classic subtypes of Folie à deux are not included in the above categories.
CASE REPORT: We found a case of shared psychotic disorder between a 38-year-old male inducer, a Batak tribe with two female recipients, 34 and 36 years from the Batak tribe. They were found to share the same delusions and hallucinations, and inducers could make recipients into trance conditions. These three individuals did not get along with the surrounding community and often carried out activities and perform rituals together.
CONCLUSION: Overall, our case has some unique features of folie à deux. In this case, there is a trance condition that can be induced that have not been reported in the literature or case reports related to Folie à deux.
Thomas Walter – entomologiste et naturaliste (1957–2019)
Authors: Jeanneret Philippe
Published: November 2019

In Memoriam Thomas Walter
Models of Arthritis Care: A Systems-level Evaluation of Acceptability as a Dimension of Quality of Care
Authors: Carr Eloise C.J. , Ortiz Mia M. , Patel Jatin N. , Barber Claire E.H. , Katz Steven , Robert Jill , Mosher Dianne , Teare Sylvia R. , Miller Jean , Homik Joanne , Dinsmore Kelly , Marshall Deborah A.
Published: November 2019

Objective.

To describe a systems-level baseline evaluation of central intake (CI) and triage systems in arthritis care within Alberta, Canada. The specific objectives were to (1) describe a process for systems evaluation for the provision of arthritis care; (2) report the findings of the evaluation for different clinical sites that provide arthritis care; and (3) identify opportunities for improving appropriate and timely access based on the findings of the evaluation.

Methods.

The study used a convergent mixed methods design. Surveys and semistructured interviews were the main data collection methods. Participants were recruited through 2 rheumatology clinics and 1 hip and knee clinic providing CI and triage, and included patients, referring physicians, specialists, and clinic staff who experienced CI processes.

Results.

A total of 237 surveys were completed by patients (n = 169), referring physicians (n = 50), and specialists (n = 18). Interviews (n = 25) with care providers and patients provided insights to the survey data. Over 95% of referring physicians agreed that the current process of CI was satisfactory. Referring physicians and specialists reported issues with the referral process and perceived support in care for wait-listed patients. Patients reported positive experiences with access and navigation of arthritis care services but expressed concerns around communication and receiving minimal support for self-management of their arthritis before and after receiving specialist care.

Conclusion.

This baseline evaluation of CI and triage for arthritis care indicates satisfaction with the service, but areas that require further consideration are referral completion, timely waiting lists, and further supporting patients to self-manage their arthritis.
La psychologisation de l'intervention sociale : paradoxes et enjeux
Authors: Bresson Maryse
Published: November 2019

Résumé La psychologisation de l’intervention sociale est, aujourd’hui encore, une expression polémique dans le monde de l’intervention sociale comme parmi les chercheurs en sociologie et en psychologie. Cet article revient sur les liens complexes entre transformations sociétales, individualisation des politiques sociales et psychologisation de l’intervention sociale. Il étudie dans quelle mesure l’accompagnement peut être considéré comme une modalité d’intervention « psychologisée », en mettant en évidence ses paradoxes et ses limites. Et il propose une réflexion sur les impacts des nouvelles formes d’intervention sur les enjeux de gouvernementalité et de mutation du sujet.
Le « chômage-intérim » en début de vie active : quelle socialisation salariale ? Quel accès à l’indépendance ?
Authors: Papinot Christian
Published: November 2019

Parce qu’il s’écoule désormais sept ans entre l’âge médian de fin d’études et celui de la stabilisation dans l’emploi, l’analyse de ces sas de transition prolongés au début de la vie active est essentielle pour appréhender la question de l’accès à l’autonomie des jeunes aujourd’hui. À partir de l’exemple de l’intérim comme forme emblématique d’« emploi de jeune », cet article analyse la signification de la condition intérimaire en termes de socialisation salariale, de modalités d’intégration professionnelle ou de place au travail. Il questionne la façon dont ces formes de participation en pointillé au marché du travail (forte discontinuité de l’activité professionnelle effective) peuvent contrarier des désirs d’accès à l’indépendance des jeunes.
L’école, première institution d’accueil de l’altérité : pour une société inclusive
Authors: Sarot Adeline , Moro Marie Rose
Published: November 2019

L’altérité continue de constituer, au sein de la société comme au sein de l’institution scolaire, une source d’angoisses, de tensions et de malentendus. La recherche transculturelle a permis d’identifier les facteurs de vulnérabilité et de protection liés à cette situation transculturelle. Elle a montré l’importance de la transmission de la langue maternelle nous amenant à réinterroger nos modèles scolaires monoculturels. Elle a aussi mis en évidence les effets potentiellement négatifs du contre-transfert culturel, également à l’œuvre au sein de l’école. Afin d’accompagner les professionnels scolaires, les élèves et leurs parents dans l’élaboration de cette diversité, nous avons développé le premier dispositif de médiation scolaire transculturelle, qui s’inscrit dans le nouveau modèle de l’inclusion, scolaire comme sociétale.
The Fairground Noise
Authors: Trowell Ian
Published: November 2019

La foire ambulante est présente dans l’histoire et la culture de nombreuses sociétés. Dans la plupart des cas, il s’agit d’une activité mercantile fondée sur le divertissement, à base de manèges, de jeux et de spectacles. La foire a ceci de spécifique qu’elle est nomade, qu’elle investit des espaces pré-existants, et qu’elle transforme l’environnement et son ambiance en leur conférant une dimension festive et électrisante. Le son joue un rôle central dans le phénomène de la foire : volume, sons inhabituels et cacophonie prennent le pas sur la trame sonore de la vie quotidienne. Dans cet article, je reviens sur l’histoire du son dans l’univers de la foire, puis je m’intéresse aux manières d’en faire la description, me demandant enfin si une telle cacophonie est propre à la foire ou peut se rencontrer ailleurs.
A Pattern Dictionary for Natural Language Processing
Authors: Hanks Patrick , Pustejovsky James
Published: November 2019

Résumé Cet article passe en revue de façon succincte trois des ressources principales utilisées actuellement pour la désambiguïsation lexicale (WordNet, FrameNet et les classes de Levin), et propose une approche alternative, en prenant comme point de départ les verbes et leurs valences. Cette nouvelle approche ne tente pas de rendre compte de tous les usages possibles d’un mot, mais plutôt de tous ses usages normaux (les ‘normes’). Les patrons normaux d’utilisation des verbes sont dégagés par une méthode que nous appelons Corpus Pattern Analysis (CPA, analyse des patrons basée sur les corpus). A chaque patron se trouve associé un sens (une ‘implication principale’). Les patrons sont ensuite utilisés comme des étalons par rapport auxquels on peut mesurer le sens probable de n’importe quelle phrase. Nous abordons aussi le statut des usages anormaux ou inhabituels (les ‘exploitations’). Nous reconnaissons aussi trois types d’alternance : les alternances syntaxiques liées à la diathèse, les alternances de type sémantique et les alternances lexicales.
Student and Community Outcomes in Service-Learning: Part 2--Community Outcomes
Authors: Reising Deanna L. , Allen Patricia N. , Hall Susan G.
Published: November 2019

This article is the second of a two-part series reporting outcomes from a service-learning program implemented in a bachelor of science in nursing program. Part 1 (on pages 512-515) described students’ perceptions of outcomes realized from the program, and Part 2 describes the community outcomes. The purposes of the program were to provide students with history-taking, blood pressure, and heart rate assessment skills, and beginning counseling skills, as well as to provide the university community with blood pressure screening and counseling in a convenient and accessible location. Data on community outcomes were collected on a continual basis during the hypertension screening and counseling program implementation. Clients were anonymously surveyed on health behavior actions taken after their screening and on the screening process. More than 700 client screenings were performed over 2 years, with positive health behavior changes being reported by clients.

Student and Community Outcomes in Service-Learning: Part 1—Student Perceptions
Regionally Specific Economic Impact of Screening and Treating Retinopathy of Prematurity in Middle-Income Societies in the Philippines
Authors: Naguib Mina M. , Soares Rebecca R. , Anzures Rachelle , Kamel Joanne , Chandrasekar Eeshwar K. , Rothschild Michael , Fernandes Alcides , Paul Chan R. V. , Olsen Timothy W.
Published: November 2019

Purpose:

To estimate the economic effects of implementing a universal screening and treatment program for retinopathy of prematurity (ROP) in the Philippines with the Economic Model for Retinopathy of Prematurity (EcROP).

Methods:

The EcROP is a cost-effectiveness, cost-benefit, and cost-utility analysis. Fifty parents of legally blind individuals (aged 3 to 28 years) from three schools for the blind in the Philippines were interviewed to estimate the societal burden of raising a blind child. A decision tree analytic model, with deterministic and probabilistic sensitivity analysis, was used to calculate the incremental cost-effectiveness ratio (primary outcome) and the incremental monetary benefit (secondary outcome) for implementing an optimal national ROP program, compared to estimates of the current policy. Findings were extrapolated to estimate the national economic benefit of an ideal screening and treatment program.

Results:

The incremental cost-effectiveness ratio for a national program over the current policy was strongly favorable to the ideal program for the Philippines and represents an opportunity for substantial societal cost savings. The per-child incremental, annual monetary benefit of a national program over the current policy was $2,627. Extrapolating to the population of children at risk in 1 year showed that the national annual net benefit estimate would be $64,320,692, which is favorable to the current policy.

Conclusions:

The EcROP demonstrates that implementing a national ROP screening and treatment program is cost-saving and cost-effective, and would substantially decrease childhood blindness in the Philippines.

[
J Pediatr Ophthalmol Strabismus
. 2019;56(6):388–396.]
Chemical and morphological characterization of Allium tuncelianum (Amaryllidaceae) and its antioxidant and anticholinesterase potentials
Authors: Karakaya Songul , Eksi Gulnur , Koca Mehmet , Demirci Betul , Kaymak Haluk Caglar , Kaplan Mehmet Emin , Aksakal Ozkan
Published: November 2019

Alzheimer’s disease is the main reason for dementia, which increases with age. Cholinesterase inhibition and antioxidant potentials of extracts and essential oils from bulbs of A. tuncelianum (Kollmann) Özhatay & al., an endemic species to Tunceli (easthern Turkey), were evaluated. The fraction extracted of ethyl acetate had the highest phenolics level, 1,1-diphenyl-2-picrylhydrazyl, and thiobarbituric acid antioxidant capacity. Also, the ethyl acetate fraction presented the highest acetylcholinesterase (15.98 ± 2.76%), and butyrylcholinesterase inhibition (47.33 ± 3.27%). Diallyl disulfide (49.8%), diallyl trisulfide (27.9%) and allyl methyl trisulfide (6.9%) were found to be the major components of essential oil. This paper shows that the ethyl acetate fraction of A. tuncelianum could be a potent source of antioxidant and anticholinesterase components.
Herniaria alpina (Caryophyllaceae) in the Iberian Peninsula
Authors: Guardiola Bufí Moisès
Published: November 2019

Herniaria alpina Chaix is a southern European orophyte distributed in the Alps, Apennines and the Pyrenees. In the Pyrenees it is considered a rare species because it is only known from few locations of the northern side (France) and there are no citations in the southern side (Spain). In summer 2018, a population was found in the Catalan Pyrenees (northeastern Iberian Peninsula). A complete description is presented and an identification key is included as an amendment for its taxonomic treatment in Flora iberica. Its current Pyrenean distribution, habitat and phenology are also reported. The conservation status is evaluated under the IUCN regional and national levels.
CD31 Acts as a Checkpoint Molecule and Is Modulated by FcγR-Mediated Signaling in Monocytes
Authors: Merchand-Reyes Giovanna , Robledo-Avila Frank H. , Buteyn Nathaniel J. , Gautam Shalini , Santhanam Ramasamy , Fatehchand Kavin , Mo Xiaokui , Partida-Sanchez Santiago , Butchar Jonathan P. , Tridandapani Susheela
Published: November 2019

Monocytes and macrophages express FcγR that engage IgG immune complexes such as Ab-opsonized pathogens or cancer cells to destroy them by various mechanisms, including phagocytosis. FcγR-mediated phagocytosis is regulated by the concerted actions of activating FcγR and inhibitory receptors, such as FcγRIIb and SIRPα. In this study, we report that another ITIM-containing receptor, PECAM1/CD31, regulates FcγR function and is itself regulated by FcγR activation. First, quantitative RT-PCR and flow cytometry analyses revealed that human monocyte FcγR activation leads to a significant downregulation of CD31 expression, both at the message level and at surface expression, mainly mediated through FcγRIIa. Interestingly, the kinetics of downregulation between the two varied, with surface expression reducing earlier than the message. Experiments to analyze the mechanism behind this discrepancy revealed that the loss of surface expression was because of internalization, which depended predominantly on the PI3 kinase pathway and was independent of FcγR internalization. Finally, functional analyses showed that the downregulation of CD31 expression in monocytes by small interfering RNA enhanced FcγR-mediated phagocytic ability but have little effect on cytokine production. Together, these results suggest that CD31 acts as a checkpoint receptor that could be targeted to enhance FcγR functions in Ab-mediated therapies.
Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4
Authors: Debrie Anne-Sophie , Mielcarek Nathalie , Lecher Sophie , Roux Xavier , Sirard Jean-Claude , Locht Camille
Published: November 2019

Pertussis is a severe respiratory disease mainly caused by Bordetella pertussis. Despite wide global vaccination coverage with efficacious pertussis vaccines, it remains one of the least well-controlled vaccine-preventable diseases, illustrating the shortcomings of the current vaccines. We have developed the live attenuated nasal pertussis vaccine BPZE1, currently undergoing clinical evaluation in human phase 2 trials. We have previously shown that in mice, BPZE1 provides strong and long-lasting protection against B. pertussis challenge by inducing potent Ab and T cell responses as well as secretory IgA and IL-17–producing resident memory T lymphocytes in the nasal cavity. In this study, we show that BPZE1 induces protection in mice against B. pertussis within days after vaccination, at a time when Ab and T cell responses were not detectable. Early protection was independent of T and B cell responses, as demonstrated by the use of SCID mice. Instead, it was due to TLR4-dependent signaling through the MyD88-dependent pathway of the innate immune response, as demonstrated in experiments with TLR4-deficient and MyD88-knockout mice. TLR2-dependent signaling did not play a major role in early protection. In addition, this study also shows that even at high doses, BPZE1 is safe in the severely immunocompromised MyD88-deficient mice, whereas virulent B. pertussis caused a severe pathological condition and death in these mice, even at a low dose. Finally, coadministration of virulent B. pertussis with BPZE1 did not cause exacerbated outgrowth of the virulent strain, thereby adding to the safety profile of this live vaccine candidate.