bluuebunny/crossref_metadata_2025 huggingface dataset:
Inteligencia artificial en el campo de la educación de Lengua y Literatura
Authors: Vera-Flores Karina Briggitte , Cerna-Vinueza Andrea Mercedes , Nivela-Cornejo María Alejandrina , Vergel-Parejo Elizabeth Esther
Published: November 2024

La Inteligencia Artificial incide en la experiencia de aprendizaje; no obstante, existe desconocimiento sobre sus limitaciones y beneficios; por lo que se realizó el presente estudio cuyo objetivo fue generar una propuesta de capacitación para docentes sobre el uso de la Inteligencia Artificial en la asignatura de Lengua y Literatura; partiendo de un diagnóstico cuyo propósito fue determinar la percepción de estudiantes de primer año y de docentes de la asignatura de Lengua y Literatura de la Unidad Educativa Sabino Espacio Rosales Panchana, con respecto al uso de la Inteligencia Artificial. El enfoque asumido fue el mixto, con tipo de diseño Secuencial Exploratorio; el alcance fue descriptivo, y proyectivo; la población coincidió con la muestra de 38 estudiantes y 2 docentes. Como instrumentos se aplicaron una Entrevista semiestructurada y un cuestionario. Como resultados, los docentes, manifestaron una visión optimista sobre la integración de la IA; pero, señalaron tener un bajo nivel de conocimiento sobre estas herramientas. Los estudiantes, consideraron que la IA mejora el aprendizaje; su percepción sobre las limitaciones fue baja, un 84,21% consideró que manejan con destreza las diferentes aplicaciones y herramientas de IA disponibles para aprender Lengua y Literatura; su percepción sobre el conocimiento y familiaridad de la IA es alta, al contrario de los docentes. Se diseñó una propuesta de capacitación dirigida a docentes. Se concluyó que la IA ofrece herramientas que enriquecen la experiencia educativa; se recomienda aplicar la propuesta de capacitación generada y evaluar su impacto en la praxis educativa de Lengua y Literatura.
Emprendimiento, mercado de trabajo y políticas de desarrollo productivo en Ecuador: Hacia un programa de formación de emprendedores
Authors: Martínez-Hinojosa Roberto Marcelo , Wilches-Medina Alexandra Montserrat , Cárdenas-Giler David Xavier , García-Alay Richard Francisco
Published: November 2024

El emprendimiento es una característica estructural de las economías latinoamericanas, producto de altos niveles de desempleo que enfrenta la región y por qué el autoempleo se convierte en una alternativa para obtener mejores ingresos. El objetivo de la presente investigación consistió en evaluar las relaciones entre el emprendimiento, el mercado de trabajo y las políticas de desarrollo productivo en la economía ecuatoriana, con la finalidad de proponer un programa de formación de emprendedores desde la perspectiva de las ciencias económicas y sociales. Esta investigación se realizó bajo una metodología de investigación de tipo mixto, tomando en cuenta aspectos cuantitativos y cualitativos del objeto de estudio relacionado con las variables de investigación: emprendimiento, mercado de trabajo, políticas de desarrollo productivo y formación de emprendedores. El rol del emprendimiento en el desarrollo socioeconómico es extensamente reconocido y toma cada vez mayor importancia con el aumento de las tasas de desempleo, en especial, asociadas con la actual crisis mundial. En estudios realizados se señalan que el emprendimiento se ha convertido en una herramienta clave para atender directamente la problemática del desempleo. Los emprendimientos creados por personas jóvenes, están generando fuentes de empleo en los países latinoamericanos, no solamente en el autoempleo, sino también, un porcentaje significativo de los nuevos emprendimientos brindan más de seis empleos. En Ecuador, desde el año 2003 hasta la actualidad, se han venido desarrollando planes de apoyo al emprendimiento, en algunos años con mayor fuerza que en otros. A lo largo de los varios años de estudio, la Actividad Emprendedora Temprana (TEA) tuvo un importante incremento, especialmente en el año 2013, donde se dice que se vivió un “boom” de emprendimientos en Ecuador, con una TEA que alcanzó el 36%. Esto se debe a que existió un mayor apoyo del sector privado y público al emprendimiento por oportunidad.
Enfoques del Marketing para Contextos Internacionales en Relación con el Branding
Authors: Ponce-Andrade , Ana Lucia , Tapia-Espinoza Nancy Janneth
Published: November 2024

Este trabajo tiene como objetivo aproximar el análisis del marketing de una firma comercial hacia decisiones estratégicas en relación con el branding, la colocación de productos y la selección de marcas para contextos internacionales en particular enfocado en el mercado latinoamericano, para lo cual se contó con los insumos que provienen del análisis las jerarquías culturales locales, el marketing regional de productos y sus procesos cognitivos; evidenciándose ideas contrapuestas entre lo local y lo global, para la conceptualización de las firmas a través de su imagen asociada a una marca más allá de las fronteras; con sentido estratégico, financiero y público.
Em vez de notícias das margens, um pedaço de horizonte
Authors: Cantarino Carolina
Published: November 2024

A proposta deste artigo é pensar com a filosofia de Paul B. Preciado as intensas transformações do mundo contemporâneo. Abordaremos os regimes de poder na/da sua filosofia e o modo como eles estão em sincronia com uma série de outras avaliações da filosofia contemporânea, compondo, dessa maneira, um esforço político coletivo para criar novos modos de pensamento diante de um mundo em transição, no qual o exercício dos poderes e a resistência política ocorrem na dimensão material intensiva dos corpos, da vida e da subjetividade. Trataremos também das políticas de identidade características da modernidade antropocêntrica e dos novos modos de subjetivação em sua coexistência e/ou dissidência em relação aos exercícios do poder na atualidade.
Entre o testemunho e a alteridade
Authors: Raveli Flávia Albergaria
Published: November 2024

O texto investiga as relações entre o estatuto do testemunho e da alteridade no trabalho de construção de sentido de uma experiência antropológica, qual seja, a do encontro entre a antropóloga e o urso. Trata-se, portanto, de uma mudança de paradigma da posição do observador e seu objeto. No livro, Martin institui uma relação de horizontalidade entre antropóloga e seu objeto, representado pelo urso. Essa situação coloca a própria antropóloga, a qual cabe a elaboração de sentido da experiência, numa condição de testemunha e intérprete do vivido.
Borges, quase infinito
Authors: Perdomo Maria Cristina
Published: November 2024

Borges e sua leitura de infinitas ressonâncias. Borges infinito em seus desdobramentos. Borges infinito nas suas provocações, Borges infinito a nos desconstruir. Borges, enfim, sem fim...Infinito! Borges igual a si mesmo, Borges no encontro do outro que é (seu) Eu; que é Ele (o outro) Eu. Borges duplicado e duplicando ao infinito, no jogo de miragens de espelhos, de veredas que se bifurcam, de corredores de Biblioteca, perdido, e se encontrando a partir do labirinto.
canto do rouxinol
Authors: Lorenzon João Paulo
Published: November 2024

Quando vamos ao teatro, podemos tropeçar em nossos buracos, em nossas margens, em nossos equívocos. Tropeçamos, com sorte, no não sentido, aquilo que surge de uma estranheza e rompe com nossa ordem estabelecida. Ordem encrustada dentro nós pela força do hábito, adquirida pelo condicionamento social e não por nossa escolha libertária.
GOSSIPIBOMA INTRA-ABDOMINAL: UMA SÉRIE DE CASOS
Authors: Sena Érico Bezerra de , Santos Orlando José dos , Soares Yure Mendes , Carvalho Mateus Balbino Barbosa de
Published: November 2024

INTRODUÇÃO: Gossipibomas podem ser definidos como materiais cirúrgicos esquecidos no campo cirúrgico após o procedimento. Abdome, pelve e tórax são, os sítios mais comuns, sendo 56% casos de gossipibomas intra-abdominais. O quadro clínico é variável. Pode cursar com obstrução intestinal, peritonite, fístula e abscesso. OBJETIVO: Relatar uma série de casos de gossipibomas intra-abdominais registrados durante julho de 2021 e julho de 2023 em um hospital de urgência e emergência, localizado em São Luís, Maranhão. MÉTODOS: Estudo descritivo, retrospectivo, observacional e de caráter qualitativo de uma série de casos. RESULTADOS E DISCUSSÃO: Os pacientes com gossipiboma apresentam um quadro clínico relacionado à localização do corpo estranho deixado durante o procedimento cirúrgico. Quando o material permanece no espaço peritoneal, os sintomas variam de dor abdominal leve a complicações graves, como perfuração visceral, obstrução intestinal, formação de fístulas e até sepse, especialmente em reações exsudativas. Nos casos relatados, foram observados cinco casos de dor abdominal, quatro de náuseas e vômitos, quatro com sinais de abdômen agudo obstrutivo e dois com dor pélvica, sintomas que são consistentes com a literatura. Os fatores de risco associados ao aumento da incidência de gossipiboma incluem procedimentos cirúrgicos de emergência, prolongados, mudança não planejada no curso de um procedimento, envolvimento de mais de uma equipe cirúrgica e pacientes com maior índice de massa corporal. CONCLUSÃO: A ocorrência de gossipibomas é um quadro que deve ser ativamente pesquisado por toda a equipe, em especial, durante o ato cirúrgico, por meio da sistematização dos tempos cirúrgicos, contagem e conferência de materiais, compressas, gazes, fios e agulhas e entrosamento entre os membros da equipe, afim de mitigar um quadro de alta morbimortalidade facilmente evitável.
DEEP LEARNING METHODS COMPARISON ON IMAGES OF TOMATO AND CUCUMBER LEAF IDENTIFICATION
Authors: KIRNAP Ahmet , BİNGÖL Mehmet Safa , ŞAHİN Fikri
Published: November 2024

Deep learning and image processing applications have become widespread, thanks to hardware developments and increased processing power. The use of technology in agriculture is increasing rapidly with the development of technology. One of the recent applications of technology in agriculture is image processing applications using deep learning. Image processing is aimed at sustainable agriculture. Deep learning is used in applications such as disease detection, agricultural spraying, maturity granding, irrigation, fertilization. In this study, deep learning models AlexNet and SqueezeNet are used to classify tomato and cucumber leaf images. 30 tomato leaves and 30 cucumber leaves are photographed to create the dataset used in the study. Afterwards, the images obtained are increased with data augmentation methods and a data set is created. The dataset consists of 2 classes and a total of 300 images. The data set is used 70% for training and 30% for validation. The results obtained from AlexNet and SqueezeNet deep learning models are given comparatively.
O USO DO PHET COLORADO COMO RECURSO PEDAGÓGICO PARA O ENSINO DE CIRCUITOS ELÉTRICOS NO ENSINO MÉDIO
Authors: Da Silva Silvio Luiz Rutz , Patel Ivo
Published: November 2024

O estudo aborda a questão central de como superar as limitações do ensino tradicional de circuitos elétricos no Ensino Médio, especialmente em contextos com recursos laboratoriais limitados. O objetivo é investigar a eficácia do simulador PhET Colorado como ferramenta pedagógica para facilitar a compreensão dos conceitos de circuitos elétricos, promovendo uma abordagem interativa que combina teoria e prática. A pesquisa foi aplicada em uma turma de terceiro ano do Ensino Médio, onde os alunos puderam manipular variáveis como resistência e tensão em simulações de circuitos, favorecendo o entendimento de conceitos complexos como a Lei de Ohm. Os principais resultados indicam que o PhET Colorado não só facilita a compreensão dos conteúdos, mas também estimula o protagonismo e o pensamento crítico dos estudantes, engajando-os ativamente no processo de aprendizado. A simulação interativa mostrou-se eficaz para o desenvolvimento de habilidades cognitivas e uma maior retenção dos conteúdos, superando as limitações das metodologias expositivas tradicionais. Conclui-se que o PhET é uma ferramenta acessível e inclusiva, que democratiza o ensino de Física ao proporcionar uma experiência prática e significativa, alinhada às demandas da educação contemporânea. Como perspectivas futuras, o estudo sugere a exploração do PhET em outras áreas da Física e a integração com metodologias colaborativas, como a aprendizagem baseada em problemas, para enriquecer ainda mais o ensino científico e incentivar a troca de conhecimentos entre os alunos em um ambiente interativo e de reflexão crítica.
GESTÃO DE RESÍDUOS SÓLIDOS: UM OLHAR SOBRE OS MUNICÍPIOS DE VIDEIRA E CAÇADOR-SC E CIDADES DO MÉXICO, SOB A LUZ DO PRINCÍPIO RESPONSABILIDADE DE HANS JONAS
Authors: Grutzmacher Nílvia Luzia , Bonin Joel Cezar , Da Silva Madalena Pereira
Published: November 2024

Solid waste management is one of the main challenges of contemporary cities, intensified by population growth, excessive consumption and uncontrolled industrialization. The selective collection of recyclable materials stands out as a crucial public policy to promote sustainability, reduce environmental impacts, and conserve natural resources. This study compares the practices of selective collection in the municipalities of Videira and Caçador, in the Midwest of Santa Catarina, with emphasis on the National Solid Waste Policy (PNRS), with reference cities in Mexico, such as Cozumel (Quintana Roo) and Salinas Victoria (Nuevo León), evaluating the public policies implemented and their respective results. These municipalities, both in Brazil and Mexico, have similar demographic characteristics, facilitating a comparative analysis of solid waste management practices. In addition, Hans Jonas' philosophical perspective is incorporated, as the research also explores the need for an ethics of responsibility in solid waste management, emphasizing the importance of considering the long-term consequences of human actions on the environment and future generations. In addition, this work is aligned with Sustainable Development Goals (SDGs) 11 and 12, which aim to promote sustainable cities and communities and ensure sustainable production and consumption patterns, respectively. Thus, the analysis of selective collection policies in Videira and Caçador and in the Mexican cities of Cozumel and Salinas Victoria was conducted in the light of a bibliographic, interpretative, qualitative approach.
AS TECNOLOGIAS DIGITAIS DE COMUNICAÇÃO E INFORMAÇÃO: UMA DISCUSSÃO CONSIDERANDO AS DIRETRIZES NACIONAIS CURRICULARES DO CURSO DE MEDICINA
Authors: Diogo Mayara Athanázio , Ferreira Diego , Batista Andréia Jayme , Braga Francisco Carneiro
Published: November 2024

Este artigo tem como objetivo examinar o papel das tecnologias digitais de comunicação e informação (TDCI) no contexto do ensino médico, à luz das Diretrizes Nacionais Curriculares (DNC) do curso de Medicina. O estudo trará um breve marco histórico a respeito da evolução dos processos de educação médica que culminaram na inserção das TDIC no Brasil com destaque na formação médica, além de realizar uma reflexão crítica dos aspectos positivos e negativos a respeito da inserção das TDIC no processo ensino-aprendizagem e os desafios da inclusão dessas tecnologias no curso de medicina. Questões relacionadas à infraestrutura, capacitação docente e avaliação também são abordadas. Com o avanço rápido da tecnologia, as TDCI têm se tornado cada vez mais presentes no cenário educacional, oferecendo oportunidades e desafios únicos para a formação médica. O artigo revisa as DNCs, destacando a importância da integração das TDIC no currículo médico para promover uma educação eficaz e atualizada. Além disso, discute-se a influência das TDIC no processo ensino-aprendizagem, enfatizando a necessidade de habilidades digitais entre os futuros médicos. Por fim, são oferecidas recomendações para a incorporação eficaz das TDIC no ensino médico, visando preparar os estudantes para as demandas de uma prática médica moderna e tecnologicamente avançada.
A BIOMEDICINA COMO FERRAMENTA ESSENCIAL NA SAÚDE DO TRABALHADOR E NA PREVENÇÃO DE RISCOS LABORAIS: UM ESTUDO EPIDEMIOLÓGICO
Authors: de Oliveira Heleise Faria dos Reis , Freitas Elaine Cristina , De Oliveira José Ricardo Lourenço , Salomão Raiane Gobira , Da Costa Helber Barcellos , Zavadinack e Silva Marina
Published: November 2024

A Biomedicina é essencial e parceira na saúde preventiva do trabalhador, auxiliando na identificação precoce de alterações de saúde advindas do ambiente laboral. Os exames laboratoriais periódicos tendem a destacar os fatores de risco associados a condições de trabalho. O objetivo deste estudo foi identificar padrões bioquímicos e hematológicos em trabalhadores expostos a riscos ocupacionais. A metodologia de estudo foi de caráter descritivo, quantitativo e epidemiológico, com análise de 3.428 exames laboratoriais de 1.145 trabalhadores, abrangendo bioquímica, hematologia, imunologia e toxicologia. Os resultados, revelaram alterações em 5% dos exames, com destaque para enzimas hepáticas e glicemia na bioquímica, além de hemogramas completos na hematologia, sugerindo hábitos de vida e ou estresse metabólico e inflamações associados ao ambiente laboral. Conclui-se que monitoramento laboratorial regular é crucial para diagnósticos precoces, redução de riscos ocupacionais e desenvolvimento de estratégias preventivas, promovendo a saúde e qualidade de vida do trabalhador.
VALORES CULTURAIS ORGANIZACIONAIS E A INSERÇÃO FEMININA NO MERCADO DE TRABALHO: UMA PERSPECTIVA ATRAENTE PARA MULHERES
Authors: Neto Inácio Ferreira Façanha , Façanha Josanne Cristina Ribeiro Ferreira , Novaes Irlane Regina Moraes
Published: November 2024

This article aims to investigate which cultural values of a company are attractive to women. Based on a survey released by the company Love Mondays (2016), which heard more than 25 thousand female professionals and highlighted the 20 best companies to work for, it was sought what each company has as organizational values, as well as the benefits they provide to their employees in order to become more attractive than the others,  justifying the research by the possibility of contributing to reflection and discussion on these cultural values For this, the research was developed from a descriptive, qualitative, bibliographic and documentary methodology, using as a sample the companies indicated in the aforementioned research.
POSITIVISM AND HISTORICAL-DIALECTICAL MATERIALISM: EPISTEMOLOGICAL INFLUENCES ON BRAZILIAN EDUCATION
Authors: Pacheco Rafael Araujo , Vieira Mariana Gomide
Published: November 2024

Epistemology can be understood as the theory of knowledge, establishing a direct link with the ways of constructing and doing Science, with the deepening and understanding of the nature of the Sciences and their paradigms in the various areas of knowledge. The understanding of epistemological currents implies the theoretical and methodological guidance desired in scientific research. In this article, we will address some of the systems of epistemological thought that influenced the process of scientific production in the field of school education: Positivism and Historical-Dialectical Materialism. As a study methodology for such an approach, a literature review was carried out, adopting the approach of narrative review with support, in particular, in Gamboa (2012), Oliveira (2010), Vasconcelos (2017), Triviños (1987) and Saviani (2005), relating the epistemological bases for the construction of theoretical-practical thinking in the context of Education. With regard to Education from a positivist perspective, the influence of Comtean thought in the educational field was perceived through the curricular composition and the institutional organization focused on order and progress. With regard to Historical-Dialectical Materialism in the educational context, Marx's contributions to a popular and transformative Education, aimed at the emancipation of the dominated classes, judging the need for a distancing from traditional Education in elitist molds, is significant.
Deteksi Dini Anemia Melalui Pemeriksaan Hemoglobin Dan Penyuluhan Di Desa Batubulan Kangin Kecamatan Sukawati Kabupaten Gianyar
Authors: Tirtawati Gusti Ayu , Somoyani Ni Ketut , Rahyani Ni Komang Yuni , Erawati Ni Luh Putu Sri , Mahayati Ni Made Dwi , Purnamayanti Ni Made Dwi
Published: November 2024

Pengabdian kepada masyarakat ini bertujuan untuk melakukan deteksi dini anemia melalui pemeriksaan hemoglobin dan memberikan penyuluhan kesehatan kepada remaja di Desa Batubulan Kangin, Kecamatan Sukawati, Kabupaten Gianyar. Kegiatan pengabdian masyarakat ini dilaksanakan oleh tim Jurusan Kebidanan pada tanggal 19 Oktober 2024 di Banjar Bude Ireng, Desa Batubulan Kangin. Kegiatan meliputi skrining anemia melalui pemeriksaan hemoglobin dan penyuluhan tentang pencegahan anemia pada remaja. Hasil kegiatan pengabdian yaitu sebanyak 17 remaja berpartisipasi dalam kegiatan ini. Hasil skrining menunjukkan 7 orang (41%) terdeteksi mengalami anemia, sementara 10 orang (59%) tidak mengalami anemia. Penyuluhan tentang pencegahan anemia dilakukan untuk meningkatkan pengetahuan dan kesadaran remaja tentang pentingnya gizi seimbang dan pola hidup sehat. Kegiatan ini berhasil mengidentifikasi prevalensi anemia yang cukup tinggi di kalangan remaja peserta. Kombinasi antara skrining dan penyuluhan merupakan pendekatan efektif dalam upaya deteksi dini dan pencegahan anemia pada remaja. Namun, untuk mencapai hasil optimal, program pencegahan anemia perlu mempertimbangkan berbagai faktor seperti asupan gizi seimbang, pola makan, dan gaya hidup sehat secara menyeluruh. Penggunaan metode inovatif seperti pendidikan sebaya dan media online dapat meningkatkan efektivitas program di masa mendatang
Pengelolaan Bank Sampah, Identifikasi Permasalahan dan Rumusan Strategi Bank Sampah Desa Marga Tabanan
Authors: Posmaningsih D.A.A , Aryasih I Gusti Ayu Made , Jana I Wayan
Published: November 2024

Pengabdian kepada masyarakat ini dilaksanakan dengan metode memberikan pelayanan berupa pendampingan teknologi tepat guna, yaitu penerapan teknologi dibidang kesehatan khususnya dalam pengelolaan sampah rumah tangga yang berkaitan dengan peningkatan taraf kesehatan masyarakat. Pelatihan, yaitu keterlibatan civitas akademika dalam mengaplikasikan keilmuannya sebagai penyelenggara kegiatan dan/atau narasumber/ fasilitator pengelola Bank Sampah. Pendampingan manajemen pengelolaan Bank Sampah. Pengelolaan Bank Sampah di Desa Marga Dengan adanya pendirian bank sampah yang telah beroperasi selama 2 tahun memberikan perubahan secara langsung dan tidak langsung kepada para warga Desa Marga. Awalnya, warga Desa Marga memandang sampah sebagai suatu hal yang tidak bernilai ekonomi dan tidak ada manfaatnya.Namun sejak adanya bank sampah, warga sedikit demi sedikit mulai tergerak untuk mengumpulkan dan mengelola sampah menjadi suatu hal yang bernilai ekonomi, yaitu melalui bank sampah tersebut. Melalui kegiatan pengabdian ini, telah dirumuskan beberapa strategi pengembangan bank sampah berdasarkan lima aspek manajemen persampahan. Strategi pengembangan bank sampah didasarkan pada permasalahan dan kendala yang berhasil teridentifikasi dalam pengelolaan bank sampah di Desa Marga, yang meliputi aspek kelembagaan, pembiayaan, pengaturan, peran serta masyarakat, dan operasional. Selain lima faktor tersebut, juga terdapat faktor teknis yang juga menjadi kendala dan menghambat keberlangsungan bank sampah di Desa Marga. Strategi yang dapat dilakukan untuk mengatasi kendala serta yang dapat meningkatkan pengelolaan bank sampah di Desa Marga adalah dukungan dari instansi pemerintah setempat, pelatihan bagi para pengurus bank sampah, dan memperluas kerja sama dengan bank sampah, mitra pengepul, dan stakeholder lain yang terlibat dalam bank sampah
Study on the Extension of Critical Zones Along Tunnel Alignments and Its Impact on Structural Damage to Nearby Buildings
Authors: Tafraouti Nouaman
Published: November 2024

When tunnelling in urban environment, tunnels are unavoidably excavated in close proximity of neighbouring buildings. It is inevitable that tunnels will interact with building foundations and other existing infrastructures. Consequently, ground movements produced by tunnel works and namely settlement, can cause serious damage to existing buildings. The objective of this study is to investigate the critical area in terms of ground movements produced by tunnelling by using the gaussian distribution function which is the most famous approach used in practice engineering for studying settlements induced by tunnel excavation, combined with conventional damage risk assessment approach based on limit value of highest settlement.
Assessment of Airborne Microbial Contaminants Using Passive Sampling Technique
Authors: Wamil Nicomedes B. , Balmaceda Dexter T. , Fernandez Boots F. , Aurelio Althea A. , Belarmino Ryan H. , Camacho Jannel J. , Castro Clarisse Anne P. , Cortez Stephen Nathanielle A. , Daruca Precious Ellaine B. , Dulay Rico S. , Dumale Lorraine Jean C. , Flora Camille C. , Galdonez Federico G. , Garcia Jessica D. , Mabana Isaias B. , Manansala Graciella Mae S. , Miguel Judy Ann C. , Murillo Katherine B. , Pamada Jarence A. , Perez Dan Kenneth E. , Raguindin Senji P. , Reyes Alvin T.
Published: November 2024

The primary aim of this study was to evaluate airborne microbial contaminants in a laboratory setting using a passive sampling technique. Results indicated higher counts of bacteria in the air of the laboratory at ceiling level (total bacteria = 5.36±0.06 log10 CFU/m3; total coliform = 3.69±0.37 log10 CFU/m3) compared to near the ground (total bacteria = 5.17±0.01 log10 CFU/m3; total coliform = 3.45±0.06 log10 CFU/m3). Conversely, filamentous fungi showed higher counts closer to the ground (4.19±0.27 log10 CFU/m3) than from the ceiling (3.82±0.40 log10 CFU/m3). The total bacterial count in the air from ceiling was significantly higher than above ground level (P <0.05). High counts of total bacteria, filamentous fungi, and coliform bacteria contributed to the presence of these microorganisms on working surfaces (total bacteria = 24.17±19.08 CFU/m2; total coliform = 1.69±1.03 CFU/m2; filamentous fungi = 7.07±3.59 CFU/m2), equipment (total bacteria = 29.22±25.22 CFU/m2; total coliform = 1.47±1.05 CFU/m2; filamentous fungi = 4.87±3.83 CFU/m2), door knobs (total bacteria = 15.83±11.50 CFU/m2; total coliform = 0.33±0.00 CFU/m2; filamentous fungi = 3.83±1.83 CFU/m2), and chairs (total bacteria = 32.78±35.91 CFU/m2; total coliform = 1.11±0.16 CFU/m2; filamentous fungi = 3.44±2.74 CFU/m2). The highest count of total bacteria was observed on the chair, while the working area had the highest counts of coliform bacteria and filamentous fungi. Data from this study showed that the microbial load of bacteria and filamentous fungi in the laboratory exceeded acceptable limits. The results from this study could be used as basis in the implementation of effective aseptic techniques and rigorous laboratory practices which are essential to prevent the spread of handled microorganisms and to minimize cross-contamination from environmental microorganisms.
Arsenic Toxicosis in Animals: Mechanism Clinical Manifestations and Treatment Approaches for Arsenic Poisoning in Animals
Authors: Sharma Kranti , Sharma Mukesh , Gendlay Manoj Kumar , Shukla Namita , Bhagat Vandana
Published: November 2024

Arsenic is a naturally occurring element present in the earth in various form (arsenate, arsenite) contaminates soil, water and causes toxicity to animal as well as human beings. The main routes of exposure of humans and most animals to arsenic through the ingestion then absorption through the skin. Animals having Arsenic intoxication showing various form peracute, acute and chronic form. First treatment is to removal of contaminants, emesis is first step (in capable species), followed by activated charcoal with a cathartic and then oral administration of demulcents. If diagnosis were confirmed early treatment should be started with Dimercaprol, even is given within two hours after ingestion of the toxic metal. Intramuscular injection or intravenous injection in peanut oil because of water insolubility was the reason. Supportive therapy include fluid therapy produce additive effect and animal will improve the health condition.
Evaluating Wharton’s jelly-derived stem cell therapy in autism: Insights from a case study
Authors: Akhtar Muzamil , Nashwan Abdulqadir J
Published: November 2024

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder affecting over 2% of the global population, marked by social communication deficits and repetitive behaviors. Kabatas et al explored the efficacy and safety of Wharton’s jelly-derived mesenchymal stem cell (WJ-MSC) therapy in a 4-year-old child with ASD. Using the childhood autism rating scale and Denver II developmental screening test, significant improvements were seen after six WJ-MSC sessions, with no adverse events over 2 years. Despite promising results, the study’s single-case design limits generalizability. Larger, multi-center trials are needed to validate the findings and assess long-term effects of WJ-MSC therapy in ASD.
Optimizing bone marrow harvesting sites for enhanced mesenchymal stem cell yield and efficacy in knee osteoarthritis treatment
Authors: Nallakumarasamy Arulkumar , Shrivastava Sandeep , Ravi VR , Jeyaraman Naveen , D Avinash Gandi , Ramasubramanian Swaminathan , Jeyaraman Madhan
Published: November 2024

Knee osteoarthritis (OA) is a debilitating condition with limited long-term treatment options. The therapeutic potential of mesenchymal stem cells (MSCs), particularly those derived from bone marrow aspirate concentrate, has garnered attention for cartilage repair in OA. While the iliac crest is the traditional site for bone marrow harvesting (BMH), associated morbidity has prompted the exploration of alternative sites such as the proximal tibia, distal femur, and proximal humerus. This paper reviews the impact of different harvesting sites on mesenchymal stem cell (MSC) yield, viability, and regenerative potential, emphasizing their relevance in knee OA treatment. The iliac crest consistently offers the highest MSC yield, but alternative sites within the surgical field of knee procedures offer comparable MSC characteristics with reduced morbidity. The integration of harvesting techniques into existing knee surgeries, such as total knee arthroplasty, provides a less invasive approach while maintaining therapeutic efficacy. However, variability in MSC yield from these alternative sites underscores the need for further research to standardize techniques and optimize clinical outcomes. Future directions include large-scale comparative studies, advanced characterization of MSCs, and the development of personalized harvesting strategies. Ultimately, the findings suggest that optimizing the site of BMH can significantly influence the quality of MSC-based therapies for knee OA, enhancing their clinical utility and patient outcomes.
Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis
Authors: Manjunatha Bhari Sharanesha , Handge Keshav T , Shah Vandana Sandeep , Al-Thobaiti Yasser Eid , Pateel Deepak Gowda Sadashivappa
Published: November 2024

BACKGROUND

One of the main characteristics of oral squamous cell carcinoma (OSCC) is that it metastasizes to cervical lymph nodes frequently with a high degree of local invasiveness. A primary feature of malignant tumors is their penetration of neighboring tissues, such as lymphatic and blood arteries, due to the tumor cells' capacity to break down the extracellular matrix (ECM). Matrix metalloproteinases (MMPs) constitute a family of proteolytic enzymes that facilitate tissue remodeling and the degradation of the ECM. MMP-9 and MMP-13 belong to the group of extracellular matrix degrading enzymes and their expression has been studied in OSCC because of their specific functions. MMP-13, a collagenase family member, is thought to play an essential role in the MMP activation cascade by breaking down the fibrillar collagens, whereas MMP-9 is thought to accelerate the growth of tumors. Elevated MMP-13 expression has been associated with tumor behavior and patient prognosis in a number of malignant cases.

AIM

To assess the immunohistochemical expression of MMP-9 and MMP-13 in OSCC.

METHODS

A total of 40 cases with histologically confirmed OSCC by incisional biopsy were included in this cross-sectional retrospective study. The protocols for both MMP-9 and MMP-13 immunohistochemical staining were performed according to the manufacturer’s recommendations along with the normal gingival epithelium as a positive control. All the observations were recorded and Pearson’s χ ² test with Fisher exact test was used for statistical analysis.

RESULTS

Our study showed no significant correlation between MMP-9 and MMP-13 staining intensity and tumor size. The majority of the patients were in advanced TNM stages (III and IV), and showed intense expression of MMP-9 and MMP-13.

CONCLUSION

The present study suggests that both MMP-9 and MMP-13 play an important and independent role in OSCC progression and invasiveness. Intense expression of MMP-9 and MMP-13, irrespective of histological grade of OSCC, correlates well with TNM stage. Consequently, it is evident that MMP-9 and MMP-13 are important for the invasiveness and progression of tumors. The findings may facilitate the development of new approaches for evaluating lymph node metastases and interventional therapy techniques, hence enhancing the prognosis of patients diagnosed with OSCC.
Prognostic factors for acute central retinal artery occlusion treated with hyperbaric oxygen: The Hong Kong study report number five
Authors: Au Sunny Chi Lik , Chong Steffi Shing Yee
Published: November 2024

BACKGROUND

Central retinal artery occlusion (CRAO) is a potentially blinding disease, and hyperbaric oxygen therapy (HBOT) is becoming increasingly popular with the support of scientific evidence. Despite the presence of various acute management measures, there is no clear evidence on the gold standard treatment for CRAO.

AIM

To identify factors and imaging parameters associated with good visual outcome, which guide ophthalmologists in the triage of CRAO patients for HBOT.

METHODS

Patients who suffered from CRAO and had a symptom onset ≤ 6 h were recruited for a course of HBOT in a tertiary hospital after failing bedside treatment. Patient demographics, onset time, CRAO eye parameters, and past medical history were prospectively collected. Visual outcomes after HBOT were also analyzed.

RESULTS

A total of 26 patients were included; the female-to-male ratio was 1:1.6, and the mean age was 67.5 years ± 13.3 years (range 44–89 years). The mean duration of follow-up and mean visual acuity (VA) improvement were 10.0 mo ± 5.3 mo and 0.48 logarithm of minimal angle of resolution (logMAR) ± 0.57 logMAR (approximately 9 letters in ETDRS) (P = 0.0001, Z = -3.67), respectively. The 1 mm zone of central macular thickness (CMT) on optical coherence tomography was not associated with VA changes (P = 0.119); however, the 1-to-3 mm circular rim of CMT was fairly associated (P = 0.02, Spearman's coefficient = 0.45). Complete retinal perfusion time during fundus fluorescein angiography (FFA) was moderately associated (P = 0.01, Spearman's coefficient = 0.58) with visual outcome.

CONCLUSION

A thinner 1-to-3 mm circular rim of CMT, but not the central 1 mm zone, is associated with better visual outcome. A shorter perfusion delay on FFA is also associated with better visual outcome.
Hemogram-derived ratios as prognostic markers for major adverse cardiovascular events in patients with non-ST-segment elevation myocardial infarction
Authors: Bećirović Emir , Bećirović Minela , Šegalo Sabina , Bećirović Amir , Hadžić Semir , Ljuca Kenana , Papić Emsel , Ferhatbegović Lamija , Ejubović Malik , Ejubović Amira Jagodić , Kovčić Amila , Šljivo Armin , Begagić Emir
Published: November 2024

BACKGROUND

Non-ST segment elevation myocardial infarction (NSTEMI) poses significant challenges in clinical management due to its diverse outcomes. Understanding the prognostic role of hematological parameters and derived ratios in NSTEMI patients could aid in risk stratification and improve patient care.

AIM

To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events (MACE) in NSTEMI patients, potentially improving clinical outcomes.

METHODS

A prospective, observational cohort study was conducted in 2021 at the Internal Medicine Clinic of the University Hospital in Tuzla, Bosnia and Herzegovina. The study included 170 patients with NSTEMI, who were divided into a group with MACE and a control group without MACE. Furthermore, the MACE group was subdivided into lethal and non-lethal groups for prognostic analysis. Alongside hematological parameters, an additional 13 hematological-derived ratios (HDRs) were monitored, and their prognostic role was investigated.

RESULTS

Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction (NSTEMI) patients with MACE and a control group at T1 and T2. However, significant disparities emerged in HDRs among NSTEMI patients with lethal and non-lethal outcomes post-MACE. Notably, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were elevated in lethal outcomes. Furthermore, C-reactive protein-to-lymphocyte ratio (CRP/Ly) at T1 (> 4.737) demonstrated predictive value [odds ratio (OR): 3.690, P = 0.024]. Both NLR at T1 (> 4.076) and T2 (> 4.667) emerged as significant predictors, with NLR at T2 exhibiting the highest diagnostic performance, as indicated by an area under the curve of 0.811 (95%CI: 0.727-0.859) and OR of 4.915 (95%CI: 1.917-12.602, P = 0.001), emphasizing its important role as a prognostic marker.

CONCLUSION

This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMI patients. During follow-up, NLR, PLR, and CRP/Ly offer important insights into the inflammatory processes underlying cardiovascular events.
Advancements in diabetic retinopathy: Insights and future directions
Authors: Cheng Chun-Yao , Hao Wen-Rui , Cheng Tzu-Hurng
Published: November 2024

This editorial discusses recent advancements and ongoing challenges in diabetic retinopathy, as reviewed by Morya et al in their comprehensive analysis. In their review, Morya et al discussed the pathophysiology of diabetic retinopathy and explored novel treatment modalities. This editorial highlights the importance of these advancements and emphasizes the need for continued research and innovation for the enhanced management of diabetic retinopathy. It also reflects upon the implications of the authors’ review findings for clinical practice and future research directions, underscoring the potential of emerging therapies for improving patient outcomes and providing a deeper understanding of disease mechanisms.
Frecuencia de anemia en niños preescolares y factores de riesgo asociados
Authors: Mascareño Alaniz Manuel Arturo , Soria Pérez José Luis
Published: November 2024

El artículo analiza la prevalencia de anemia en niños preescolares en un hospital de Michoacán, México, y los factores de riesgo asociados. Con un estudio descriptivo y transversal, se recolectaron datos de 362 niños de 2 a 5 años entre febrero y octubre de 2023. Los resultados indican una prevalencia de anemia del 29.2%, con mayor frecuencia en niños de 2 años y en el sexo masculino. La anemia se asoció significativamente con factores como bajo peso al nacer, prematuridad y alimentación con sucedáneos en lugar de lactancia materna. Los niños con bajo peso mostraron un riesgo elevado, mientras que aquellos que recibieron suplementación con hierro presentaron menos casos de anemia. El estudio concluye que la anemia en preescolares es un problema de salud relevante, y recomienda reforzar la vigilancia nutricional y las intervenciones en este grupo, destacando la importancia de la atención temprana y la suplementación. Estos hallazgos son críticos para orientar políticas de salud pública que mejoren la nutrición y reducen la anemia en poblaciones vulnerables.
Functional Materials as an Innovative Approach to Sportswear Design
Authors: Çetin Kardelen , Bayburtlu Irmak
Published: November 2024

The textile industry has become more interested in the sports sector, as well as many other industrial sectors, as a result of the growing popularity of sport around the world and the rise in the number of participants. The apparel and materials created for this market are intended to satisfy the needs and preferences of the consumer when they are participating in a sporting activity. Consumers benefit from a variety of conveniences in their daily lives, including higher safety, a decreased chance of accidents, and improved athletic performance, thanks to the usage of technical and practical items in sportswear. Modern textile and apparel design and manufacture are centred on functionalization, the creation of cutting-edge features, and the application of cutting-edge technology to improve human performance. Therefore, it is a significant field for innovation. The goal of this paper is to examine specially developed materials and assemblies that go beyond their conventional uses and are intended to give the user a specific performance or capability. A number of research has been done in this area, and production of technological, intelligent, and functional textiles that offer consumers a more pleasant wearing experience and comfort in everyday life, as well as that support better performance for those interested in sport, has started to increase. The research is limited to men's and women's everyday sportswear products created in the last 10 years that are technologically advanced, inventive, and functional. A literature review based on several articles, books, magazines, newspapers, and theses, as well as digital interviews with designers and staff members of the brands that may be reached, make up the research methodology.
Palladian Manifestations in the Architectural Ensembles of 18th Century American
Authors: Tsvetkova Polina Olegovna
Published: November 2024

The article discusses the stage of formation and development of classical architectural traditions in the United States of America in relation to the ensembles of country estates and plantations of the southern states of the XVIII century. The main direction in which both foreign architects and national American masters worked was Palladianism. On the basis of local specific features and colonial traditions, this direction received a new reading. In this study, based on a phased comparative chronological analysis of outstanding examples of suburban architecture in the United States with prototypes of buildings built by A. Palladio in Italy, variations in the interpretation of the Palladian system in the United States in the 18th century are revealed. Little-studied examples of buildings and creative personalities of classical architects are given. Attention is paid to the mutual influence of the Palladian style and the Georgian architectural tradition. The main methods of developing Palladian architectural traditions in the USA are identified and described.
Gold Jewelry from the Shakhtakhty and its Cultural and Historical Context (Middle Bronze Age II millennium BC)
Authors: Rustambayova Afet Mammad
Published: November 2024

The subject of the study is an archaeological discovery of the Bronze Age (2nd millennium BC), a gold plaque-falar from the village of Shakhtakhty, Nakhichevan Autonomous Republic of Azerbaijan. The article provides a historical-typological and semantic-semiotic analysis of this piece of horse equipment made in a complex jewelry technique from thin gold foil with solar-zoomorphic symbols. The given structural-semantic analysis of its individual solar elements - circles, concentric circles, and a pictorial composition in the shape of four sheep's heads arranged swastically. In the celestial signs-codes of the golden falar, it seems possible to detect the worship of the sun, the cult of gold, nature, totems and ancestors, which is extremely closely associated with it. Celestial semantics is viewed through the paradigm of mythological and cosmogonic ideas of the population of a given cultural and historical area. The golden falar was found in a horse burial, which reflects the local traditions of their veneration. The sacralization of the horse occurred with the help of special ceremonies with its inherent symbols. The horse cult was widespread in the civilizations of many nations of the Caucasus, East and Central Asia, testifies to the emergence and consolidation of cultural innovations during the intensification of migration in this cultural and historical area. This historical resource – a jewelry item of the Bronze Age and rich funerary gifts combined with a ritual horse burial allows us to conclude about the appearance of early civilizations on the territory of Azerbaijan, as well as the emergence of a class of society, the development of jewelry craft and interaction and mutual enrichment of cultures during this period
"Irbit Fair Leaf" as a Source on the History of Ural Chest Craft
Authors: Pudov Gleb Alexandrovich
Published: November 2024

The paper deals with a periodical related to the Irbit fair – «Irbit fair leaf». This newspaper was published from 1863 to 1915. It reflected many aspects of fair life. Among them are the peculiarities of the trading activities of the owners of the chest workshops who brought their products to Irbit. Previously, this topic did not attract the attention of researchers. Nevertheless, it is important because it allows you to highlight the particulars of the chest producton, as a rule, remaining out of the field of view of zemstvo statisticians. The article publishes information about the Ural residents who came to the fair, their place of arrival, the number and types of «goods», the places of sale and some particulars of the trade activities of the «manufacturers» are specified. All this information is found on the pages of the newspaper. It is concluded that «Irbit fair leaf» is an important source on the history of the Ural chest craft of the second half of the XIX – early XX century.
Book review: Udmurt Republic: Arts and Crafts (2022)
Authors: Koshaev Vladimir Borisovich
Published: November 2024

The encyclopedia "The Udmurt Republic: Decorative and Applied Arts and Crafts" offered to the attention of readers is a thematic publication that characterizes the traditional art and culture of Udmurtia and is of great importance as an example of a modern understanding of history and the prospects for historical and artistic traditions in Russia. In the XIX - early XX century. on the territory of the republic, the former part of the Vyatka province, there were more than 1990 types of crafts for processing raw materials, on the basis of which blacksmithing and foundry skills, wood carving, patterned weaving and lint-free carpet weaving, embroidery and knitting, weaving from vines, tree roots and algae were formed, artistic processing of birch bark, etc. The publication is accompanied by a greeting from the Minister of Culture of the Udmurt Republic V.M. Solovyov, Director of the Udmurt Federal Research Center of the Ural Branch of the Russian Academy of Sciences M.Yu. Alyes, editorial annotation, as well as the Law “On the Intangible Cultural Heritage in the Udmurt Republic”, adopted by the State Council of the Udmurt Republic on June 29, 2021, and signed by the Head of the Udmurt Republic A.V. Brechalov (Izhevsk, July 14, 2021, No. 78-RZ), which indicates the understanding of the leadership of the Republic of the most important historical role of the phenomenon of folk and decorative arts in the life of the region.
Konflikt und Hybris
Authors: Wille Franz , Behrendt Eva
Published: November 2024

Vom Theater lernen, statt es kaputtzusparen