bluuebunny/crossref_metadata_2025 huggingface dataset:
Quatrains of Many Receptions: A Survey of Perceptions of ‘Omar Khayyām in Ottoman and Turkish Translations
Authors: Balıkçıoğlu Efe Murat
Published: March 2024

This article explores the wide range of responses to Persian polymath and poet ‘Omar Khayyām (d. ca. 526/1132) in Ottoman and Turkish literary sources. A great number of intellectuals, past and present, translated Khayyām's famed quatrains into Turkish, albeit with differing motivations regarding subject, style, message, and literary reception. Social critics like Abdullah Cevdet employed Khayyām's quatrains as a vehicle for proving that liberal and progressive mindsets were accommodated in classical Islam. On the other hand, literary scholars like Rıza Tevfik [Bölükbaşı], Ḥüseyin Dāniş, and Abdülbaki Gölpınarlı chose to focus on the intellectual origins of Khayyām's thought, as well as on his connections to Islamic philosophical traditions. In the first decades of the Turkish Republic, there was another wave of interest in Khayyām's quatrains related to prosody, message, and what his legacy and poetic disposition represented with regard to the Islamic past. Whereas poets like Yahya Kemal and Âsaf Hâlet Çelebi regarded him as a paragon of libertine lyrics and Sufi mysticism, Turkish leftist intellectuals such as Nâzım Hikmet, Sabahattin Eyuboğlu, and A. Kadir set him as a socialist or materialist humanist who was a staunch critic of religious bigotry and fanaticism.
A machine learning model for reconstructing skin-friction drag over ocean surface waves
Authors: Yousefi Kianoosh , Hora Gurpreet Singh , Yang Hongshuo , Veron Fabrice , Giometto Marco G.
Published: March 2024

In order to improve the predictive abilities of weather and climate models, it is essential to understand the behaviour of wind stress at the ocean surface. Wind stress is contingent on small-scale interfacial dynamics typically not directly resolved in numerical models. Although skin friction contributes considerably to the total stress up to moderate wind speeds, it is notoriously challenging to measure and predict using physics-based approaches. This work proposes a supervised machine learning (ML) model that estimates the spatial distribution of the skin-friction drag over wind waves using solely wave elevation and wave age, which are relatively easy to acquire. The input–output pairs are high-resolution wave profiles and their corresponding surface viscous stresses collected from laboratory experiments. The ML model is built upon a convolutional neural network architecture that incorporates the Mish nonlinearity as its activation function. Results show that the model can accurately predict the overall distribution of viscous stresses; it captures the peak of viscous stress at/near the crest and its dramatic drop to almost null just past the crest in cases of intermittent airflow separation. The predicted area-aggregate skin friction is also in excellent agreement with the corresponding measurements. The proposed method offers a practical pathway for estimating both local and area-aggregate skin friction and can be easily integrated into existing numerical models for the study of air–sea interactions.
How top leaders’ support affects open government data (OGD)-driven innovation capacity of firms: Based on the TOE framework perspective
Authors: Wang Yu , Jiang Hui , Han Delong , Zhou Mingle , Li Gang
Published: March 2024

The innovation value of open government data (OGD) drives firms to the participation in OGD-driven innovation. However, to fully excavate the innovation value of OGD for firms, it is essential to explore the factors and mechanisms that affect OGD-driven innovation capacity. On the basis of the technology–organization–environment (TOE) framework, a theoretical model affecting OGD-driven innovation capacity is proposed for analysis by partial least squares structural equation modeling with 236 sample data from China. The results indicate that top leaders’ support positively impacts on OGD-driven innovation capacity in firms. And we also prove that technical competence, organizational arrangement, and innovation support partially mediate the relationship between top leaders’ support and OGD-driven innovation capacity on the basis of the TOE framework. Consequently, the findings provide new research perspectives and practical guidance for promoting OGD-driven innovation capacity in firms.
Decay at infinity for solutions to some fractional parabolic equations
Authors: Banerjee Agnid , Ghosh Abhishek
Published: March 2024

For

$s\in [\tfrac {1}{2},\, 1)$

, let

$u$

solve

$(\partial _t - \Delta )^s u = Vu$

in

$\mathbb {R}^{n} \times [-T,\, 0]$

for some

$T>0$

where

$||V||_{ C^2(\mathbb {R}^n \times [-T, 0])} < \infty$

. We show that if for some

$0<\mathfrak {K} < T$

and

$\epsilon >0$

\[ {\unicode{x2A0D}}-_{[-\mathfrak{K},\, 0]} u^2(x, t) {\rm d}t \leq Ce^{-|x|^{2+\epsilon}}\ \forall x \in \mathbb{R}^n, \]

then

$u \equiv 0$

in

$\mathbb {R}^{n} \times [-T,\, 0]$

.
Managing Uncertain Times in Turkey: Refugee Healthcare Research during a Global Pandemic
Authors: Kayali Nihal
Published: March 2024

When I entered graduate school in September 2016, Turkey was mired in a series of successive crises. I had spent the first half of the year living in Istanbul, writing about the country's reception of Syrian refugees as a journalist and researcher. During that stretch, a series of suicide bombings and, in my last week in the country, an attempted coup, were formative for the way I made sense of future fieldwork in Turkey. I surmised that it would be wrought with unpredictability. My research interest in Syrian refugees’ access to Turkey's state services was itself marked by uncertainty. This uncertainty was tied to the nature of Syrians’ explicitly temporary legal status within Turkey and the broader domestic and geopolitical context that shaped the contours of Turkey's refugee policy. Given these layers of unpredictability both endogenous and exogenous to my research interest, I planned to design my research with uncertainty as an analytical focus.
Beyond a Confessional Paradigm? Richard Simon and the Vernacular Bible
Authors: TWINING TIMOTHY
Published: March 2024

This article presents a new account of Richard Simon's work as a biblical translator. Having first contextualised Simon's views on the vernacular Bible in the contested world of late seventeenth-century French Catholic biblical translation, it then examines how they were engaged with and disputed by contemporaries (in particular, Antoine Arnauld). It contends that Simon's novelty did not consist in applying history and philology to the Bible in order to reach a confessionally neutral version, but rather in reconceptualising the relationship between multiple legitimate biblical translations to craft a new form of Catholic vernacular Bible.
Experimental issues of energy balance in open magnetic trap
Authors: Soldatkina Elena I. , Meyster Andrey K. , Yakovlev Dmitry V. , Bagryansky Peter A.
Published: March 2024

The paper presents an overview of experimental results of an investigation of different energy loss channels in the gas dynamic trap (GDT), which is a magnetic mirror plasma confinement device in the Budker Institute of Nuclear Physics. Energy losses along magnetic field lines are considered as well as losses onto radial limiters, which restrict the plasma column radius and provide its magnetohydrodynamic stability via the ‘vortex confinement’ mechanism. The losses along the field lines were measured using a set of pyroelectric bolometers on the plasma absorber and the losses onto the limiters were determined with thermistors from their temperature rise. Additionally, the losses due to charge exchange of fast plasma ions on the residual neutral gas in the GDT were measured using a longitudinal array of pyroelectric bolometers mounted on the wall of the central cell. An attempt was made to draw up the energy balance in the GDT in order to identify the predominant loss channels and reduce those losses in the future.
Bringing the Constituents Back In: The Politics of Social Security in the 1950s
Authors: YELLIN ERIC S.
Published: March 2024

This article argues that scholars’ current understanding of Social Security policy making in the 1950s is missing a crucial component: massive letter-writing campaigns by ordinary Americans. Americans’ letters to Congress—and the responses of members and their aides in public debates and constituent correspondence—reflect a more vibrant, more democratic, and messier policy-making process than scholars have previously recognized. In the 1950s, Congress voted to amend the Social Security Act of 1935 repeatedly, expanding both the number of occupations covered by the Old Age and Survivors Insurance program and the level of benefits individuals received. Scholars have depicted this expansion as the work of planners within the Social Security bureaucracy. Yet, the letters in congressional records reveal that the process of amending Social Security resulted from—and helped create—constituencies of Americans who felt entitled to make claims on the federal state apparatus.
Prospective evaluation of acute neurological events after paediatric cardiac surgery
Authors: Frost Olivia , Ridout Deborah , Rodrigues Warren , Wellman Paul , Cassidy Jane , Tsang Victor T. , Dorobantu Dan , Stoica Serban C. , Hoskote Aparna , Brown Katherine L.
Published: March 2024

Objectives:

Children with CHD are at heightened risk of neurodevelopmental problems; however, the contribution of acute neurological events specifically linked to the perioperative period is unclear.

Aims:

This secondary analysis aimed to quantify the incidence of acute neurological events in a UK paediatric cardiac surgery population, identify risk factors, and assess how acute neurological events impacted the early post-operative pathway.

Methods:

Post-operative data were collected prospectively on 3090 consecutive cardiac surgeries between October 2015 and June 2017 in 5 centres. The primary outcome of analysis was acute neurological event, with secondary outcomes of 6-month survival and post-operative length of stay. Patient and procedure-related variables were described, and risk factors were statistically explored with logistic regression.

Results:

Incidence of acute neurological events after paediatric cardiac surgery in our population occurred in 66 of 3090 (2.1%) consecutive cardiac operations. 52 events occurred with other morbidities including renal failure (21), re-operation (20), cardiac arrest (20), and extracorporeal life support (18). Independent risk factors for occurrence of acute neurological events were CHD complexity 1.9 (1.1–3.2), p = 0.025, longer operation times 2.7 (1.6–4.8), p < 0.0001, and urgent surgery 3.4 (1.8–6.3), p < 0.0001. Unadjusted comparison found that acute neurological event was linked to prolonged post-operative hospital stay (median 35 versus 9 days) and poorer 6-month survival (OR 13.0, 95% CI 7.2–23.8).

Conclusion:

Ascertainment of acute neurological events relates to local measurement policies and was rare in our population. The occurrence of acute neurological events remains a suitable post-operative metric to follow for quality assurance purposes.
Socioeconomic Status and Self-Regard
Authors: Renger Daniela , Lohmann Julian F. , Renger Sophus , Martiny Sarah E.
Published: March 2024

Abstract: Past research has shown that the socioeconomic status (e.g., income or education) is associated with people’s self-evaluation, such as global self-esteem. In the present research, we argue that socioeconomic status also affects people’s belief of possessing the same rights as others (i.e., self-respect). In a cross-sectional study ( N = 298) and a longitudinal study ( N = 379), we investigated the relationships between income and education with three forms of self-regard. The only consistent finding was that income was related to self-respect over time even when controlling for self-love and self-competence, the core and well-studied components of global self-esteem. We discuss the significance of our findings with regard to social justice and democracy.
Incrimination Through Innuendo
Authors: Letourneau Danielle , Gawronski Bertram
Published: March 2024

Abstract: Research by Wegner et al. (1981) suggests that incriminating innuendo in questions can negatively affect attitudes and opinions. Two preregistered studies ( N = 506) provide a close replication of Study 1 of Wegner et al., additionally testing whether question-innuendo effects are moderated by partisanship. Replicating the original findings of Wegner et al., questions insinuating something negative about a target person reduced favorable impressions of the target. Counter to the novel hypotheses that effects of incriminating questions would be reduced for political-ingroup targets and enhanced for political-outgroup targets, question-innuendo effects did not differ across target groups. The findings suggest that merely asking a question about a false proposition can influence public opinion in the absence of incorrect assertions that could be deemed misinformation.
The Evolution of Hillslope Hydrology: Links Between Form, Function and the Underlying Control of Geology
Authors: Hartmann Anne , Blume Theresa
Published: March 2024

Form and function are two major characteristics of hydrological systems. While form summarizes the structure of the system, function represents the hydrological response. Little is known about how these characteristics evolve and how form relates to function in young hydrological systems. We investigated how form and function evolve during the first millennia of landscape evolution. We analyzed two hillslope chronosequences in glacial forelands, one developed from siliceous and the other from calcareous parent material. Variables describing hillslope form included soil physical properties, surface, and vegetation characteristics. Variables describing hydrological function included soil water response times, soil water storage, drainage, and dominant subsurface flow types. We identified links between form and hydrological function via cluster analysis. Clusters identified based on form were compared in terms of their hydrological functioning. The comparison of the two different parent materials shows how strongly landscape evolution is controlled by the underlying geology. Soil pH appears to be a key variable influencing vegetation, soil formation and subsequently hydrology. At the calcareous site, the high buffering capacity of the soil leads to less soil formation and fast, vertical subsurface water transport dominates the water redistribution even after more than 10,000 years of landscape evolution. At the siliceous site, soil acidification results in accumulation of organic material, a high water storage capacity, and in podsolization. Under these conditions water redistribution changes from vertical subsurface water transport at the young age classes to water storage in the organic surface layer and lateral subsurface water transport within 10,000 years.
Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation
Authors: Darrau Estelle , Jacquemet Elise , Pons Stéphanie , Schlick Laurène , Zouridakis Marios , Wu Ching-Lien , Richard Jean-Romain , Barau Caroline , Le Corvoisier Philippe , Yolken Robert , Tamouza Ryad , Leboyer Marion , Maskos Uwe
Published: March 2024

There is growing evidence that autoantibodies (AAbs) against proteins expressed in the brain are playing an important role in neurological and psychiatric disorders. Here, we explore the presence and the role of peripheral AAbs to the α7-nicotinic acetylcholine receptor (nAChR) in inflammatory subgroups of psychiatric patients with bipolar disorder (BD) or schizophrenia (SCZ) and healthy controls. We have identified a continuum of AAb levels in serum when employing a novel ELISA technique, with a significant elevation in patients compared to controls. Using unsupervised two-step clustering to stratify all the subjects according to their immuno-inflammatory background, we delineate one subgroup consisting solely of psychiatric patients with severe symptoms, high inflammatory profile, and significantly increased levels of anti-nAChR AAbs. In this context, we have used monoclonal mouse anti-human α7-nAChR antibodies (α7-nAChR-mAbs) and shown that TNF-α release was enhanced upon LPS stimulation in macrophages pre-incubated with α7-nAChR-mAbs compared to the use of an isotype control. These findings provide a basis for further study of circulating nicotinic AAbs, and the inflammatory profile observed in patients with major mood and psychotic disorders.
Hypoxia-induced miR-5100 promotes exosome-mediated activation of cancer-associated fibroblasts and metastasis of head and neck squamous cell carcinoma
Authors: Duan Yuansheng , Zhou Mengqian , Ye Beibei , Yue Kai , Qiao Feng , Wang Yuxuan , Lai Qingchuan , Wu Yue , Cao Jiayan , Wu Yansheng , Wang Xudong , Jing Chao
Published: March 2024

The invasion-metastasis cascade in head and neck squamous cell carcinoma (HNSCC) is predominantly caused by the interaction between tumor cells and tumor microenvironment, including hypoxia as well as stromal cells. However, the mechanism of hypoxia-activated tumor-stroma crosstalk in HNSCC metastasis remains to be deciphered. Here, we demonstrated that HIF1α was upregulated in HNSCC specimens compared with adjacent normal tissues, whose overexpression was associated with lymph node metastasis and predicted unfavorable prognosis. HIF1α expression correlated positively with the levels of miR-5100 as well as α-SMA, the marker of CAFs. Hypoxia/HIF1α regulated transcriptionally miR-5100 to promote the degradation of its target gene QKI, which acts as a tumor suppressor in HNSCC. Hypoxic HNSCC-derived exosomal miR-5100 promoted the activation of CAFs by orchestrating QKI/AKT/STAT3 axis, which further facilitated HNSCC metastasis. Additionally, miR-5100 derived from plasma exosomes indicated HNSCC malignant progression. In conclusion, our findings illuminate a novel HIF1α/miR-5100/QKI pathway in HNSCC metastasis, and suggest that miR-5100 might be a potential biomarker and therapeutic target for HNSCC.
Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation
Authors: Dong Na , Ma Hui-Xian , Liu Xue-Qin , Li Dong , Liu Ling-Hong , Shi Qing , Ju Xiu-Li
Published: March 2024

Despite progressive improvements in the survival rate of pediatric B-cell lineage acute lymphoblastic leukemia (B-ALL), chemoresistance-induced disease progression and recurrence still occur with poor prognosis, thus highlighting the urgent need to eradicate drug resistance in B-ALL. The 6-mercaptopurine (6-MP) is the backbone of ALL combination chemotherapy, and resistance to it is crucially related to relapse. The present study couples chemoresistance in pediatric B-ALL with histidine metabolism deficiency. Evidence was provided that histidine supplementation significantly shifts the 6-MP dose-response in 6-MP-resistant B-ALL. It is revealed that increased tetrahydrofolate consumption via histidine catabolism partially explains the re-sensitization ability of histidine. More importantly, this work provides fresh insights into that desuccinylation mediated by SIRT5 is an indispensable and synergistic requirement for histidine combination therapy against 6-MP resistance, which is undisclosed previously and demonstrates a rational strategy to ameliorate chemoresistance and protect pediatric patients with B-ALL from disease progression or relapse.
Engineered dityrosine-bonding of the RSV prefusion F protein imparts stability and potency advantages
Authors: Gidwani Sonal V. , Brahmbhatt Devarshi , Zomback Aaron , Bassie Mamie , Martinez Jennifer , Zhuang Jian , Schulze John , McLellan Jason S. , Mariani Roberto , Alff Peter , Frasca Daniela , Blomberg Bonnie B. , Marshall Christopher P. , Yondola Mark A.
Published: March 2024

Viral fusion proteins facilitate cellular infection by fusing viral and cellular membranes, which involves dramatic transitions from their pre- to postfusion conformations. These proteins are among the most protective viral immunogens, but they are metastable which often makes them intractable as subunit vaccine targets. Adapting a natural enzymatic reaction, we harness the structural rigidity that targeted dityrosine crosslinks impart to covalently stabilize fusion proteins in their native conformations. We show that the prefusion conformation of respiratory syncytial virus fusion protein can be stabilized with two engineered dityrosine crosslinks (DT-preF), markedly improving its stability and shelf-life. Furthermore, it has 11X greater potency as compared with the DS-Cav1 stabilized prefusion F protein in immunogenicity studies and overcomes immunosenescence in mice with simply a high-dose formulation on alum.
Triggered contraction of self-assembled micron-scale DNA nanotube rings
Authors: Illig Maja , Jahnke Kevin , Weise Lukas P. , Scheffold Marlene , Mersdorf Ulrike , Drechsler Hauke , Zhang Yixin , Diez Stefan , Kierfeld Jan , Göpfrich Kerstin
Published: March 2024

Contractile rings are formed from cytoskeletal filaments during cell division. Ring formation is induced by specific crosslinkers, while contraction is typically associated with motor protein activity. Here, we engineer DNA nanotubes and peptide-functionalized starPEG constructs as synthetic crosslinkers to mimic this process. The crosslinker induces bundling of ten to hundred DNA nanotubes into closed micron-scale rings in a one-pot self-assembly process yielding several thousand rings per microliter. Molecular dynamics simulations reproduce the detailed architectural properties of the DNA rings observed in electron microscopy. Theory and simulations predict DNA ring contraction – without motor proteins – providing mechanistic insights into the parameter space relevant for efficient nanotube sliding. In agreement between simulation and experiment, we obtain ring contraction to less than half of the initial ring diameter. DNA-based contractile rings hold promise for an artificial division machinery or contractile muscle-like materials.
The atlas of unburnable oil for supply-side climate policies
Authors: Pellegrini Lorenzo , Arsel Murat , Muñoa Gorka , Rius-Taberner Guillem , Mena Carlos , Orta-Martínez Martí
Published: March 2024

To limit the increase in global mean temperature to 1.5 °C, CO2 emissions must be drastically reduced. Accordingly, approximately 97%, 81%, and 71% of existing coal and conventional gas and oil resources, respectively, need to remain unburned. This article develops an integrated spatial assessment model based on estimates and locations of conventional oil resources and socio-environmental criteria to construct a global atlas of unburnable oil. The results show that biodiversity hotspots, richness centres of endemic species, natural protected areas, urban areas, and the territories of Indigenous Peoples in voluntary isolation coincide with 609 gigabarrels (Gbbl) of conventional oil resources. Since 1524 Gbbl of conventional oil resources are required to be left untapped in order to keep global warming under 1.5 °C, all of the above-mentioned socio-environmentally sensitive areas can be kept entirely off-limits to oil extraction. The model provides spatial guidelines to select unburnable fossil fuels resources while enhancing collateral socio-environmental benefits.
Ultra-fast switching memristors based on two-dimensional materials
Authors: Teja Nibhanupudi S. S. , Roy Anupam , Veksler Dmitry , Coupin Matthew , Matthews Kevin C. , Disiena Matthew , Ansh  , Singh Jatin V. , Gearba-Dolocan Ioana R. , Warner Jamie , Kulkarni Jaydeep P. , Bersuker Gennadi , Banerjee Sanjay K.
Published: March 2024

The ability to scale two-dimensional (2D) material thickness down to a single monolayer presents a promising opportunity to realize high-speed energy-efficient memristors. Here, we report an ultra-fast memristor fabricated using atomically thin sheets of 2D hexagonal Boron Nitride, exhibiting the shortest observed switching speed (120 ps) among 2D memristors and low switching energy (2pJ). Furthermore, we study the switching dynamics of these memristors using ultra-short (120ps-3ns) voltage pulses, a frequency range that is highly relevant in the context of modern complementary metal oxide semiconductor (CMOS) circuits. We employ statistical analysis of transient characteristics to gain insights into the memristor switching mechanism. Cycling endurance data confirms the ultra-fast switching capability of these memristors, making them attractive for next generation computing, storage, and Radio-Frequency (RF) circuit applications.
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models
Authors: Kaiser Franziska K. , Hernandez Mariana Gonzalez , Krüger Nadine , Englund Ellinor , Du Wenjuan , Mykytyn Anna Z. , Raadsen Mathijs P. , Lamers Mart M. , Rodrigues Ianiski Francine , Shamorkina Tatiana M. , Snijder Joost , Armando Federico , Beythien Georg , Ciurkiewicz Malgorzata , Schreiner Tom , Gruber-Dujardin Eva , Bleyer Martina , Batura Olga , Erffmeier Lena , Hinkel Rabea , Rocha Cheila , Mirolo Monica , Drabek Dubravka , Bosch Berend-Jan , Emalfarb Mark , Valbuena Noelia , Tchelet Ronen , Baumgärtner Wolfgang , Saloheimo Markku , Pöhlmann Stefan , Grosveld Frank , Haagmans Bart L. , Osterhaus Albert D.M.E.
Published: March 2024

Monoclonal antibodies are an increasingly important tool for prophylaxis and treatment of acute virus infections like SARS-CoV-2 infection. However, their use is often restricted due to the time required for development, variable yields and high production costs, as well as the need for adaptation to newly emerging virus variants. Here we use the genetically modified filamentous fungus expression system Thermothelomyces heterothallica (C1), which has a naturally high biosynthesis capacity for secretory enzymes and other proteins, to produce a human monoclonal IgG1 antibody (HuMab 87G7) that neutralises the SARS-CoV-2 variants of concern (VOCs) Alpha, Beta, Gamma, Delta, and Omicron. Both the mammalian cell and C1 produced HuMab 87G7 broadly neutralise SARS-CoV-2 VOCs in vitro and also provide protection against VOC Omicron in hamsters. The C1 produced HuMab 87G7 is also able to protect against the Delta VOC in non-human primates. In summary, these findings show that the C1 expression system is a promising technology platform for the development of HuMabs in preventive and therapeutic medicine.
Capturing ion trapping and detrapping dynamics in electrochromic thin films
Authors: Zhang Renfu , Zhou Qinqi , Huang Siyuan , Zhang Yiwen , Wen Rui-Tao
Published: March 2024

Ion trapping has been found to be responsible for the performance degradation in electrochromic oxide thin films, and a detrapping procedure was proved to be effective to rejuvenate the degraded films. Despite of the studies on ion trapping and detrapping, its dynamics remain largely unknown. Moreover, coloration mechanisms of electrochromic oxides are also far from clear, limiting the development of superior devices. Here, we visualize ion trapping and detrapping dynamics in a model electrochromic material, amorphous WO3. Specifically, formation of orthorhombic Li2WO4 during long-term cycling accounts for the origin of shallow traps. Deep traps are multiple-step-determined, composed of mixed W4+-Li2WO4, amorphous Li2WO4 and W4+-Li2O. The non-decomposable W4+-Li2WO4 couple is the origin of the irreversible traps. Furthermore, we demonstrate that, besides the typical small polaron hopping between W5+ ↔ W6+ sites, bipolaron hopping between W4+ ↔ W6+ sites gives rise to optical absorption in the short-wavelength region. Overall, we provide a general picture of electrochromism based on polaron hopping. Ion trapping and detrapping were demonstrated to also prevail in other cathodic electrochromic oxides. This work not only provides the ion trapping and detrapping dynamics of WO3, but also open avenues to study other cathodic electrochromic oxides and develop superior electrochromic devices with great durability.
The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans
Authors: Emerson Felicity J. , Chiu Caitlin , Lin Laura Y. , Riedel Christian G. , Zhu Ming , Lee Siu Sylvia
Published: March 2024

SET-26, HCF-1, and HDA-1 are highly conserved chromatin factors with key roles in development and aging. Here we present mechanistic insights into how these factors regulate gene expression and modulate longevity in C. elegans. We show that SET-26 and HCF-1 cooperate to regulate a common set of genes, and both antagonize the histone deacetylase HDA-1 to limit longevity. HCF-1 localization at chromatin is largely dependent on functional SET-26, whereas SET-26 is only minorly affected by loss of HCF-1, suggesting that SET-26 could recruit HCF-1 to chromatin. HDA-1 opposes SET-26 and HCF-1 on the regulation of a subset of their common target genes and in longevity. Our findings suggest that SET-26, HCF-1, and HDA-1 comprise a mechanism to fine-tune gene expression and longevity and likely have important implications for the mechanistic understanding of how these factors function in diverse organisms, particularly in aging biology.
Monolithic thin-film lithium niobate broadband spectrometer with one nanometre resolution
Authors: Finco Giovanni , Li Gaoyuan , Pohl David , Reig Escalé Marc , Maeder Andreas , Kaufmann Fabian , Grange Rachel
Published: March 2024

Miniaturised optical spectrometers are attractive due to their small footprint, low weight, robustness and stability even in harsh environments such as space or industrial facilities. We report on a stationary-wave integrated Fourier-transform spectrometer featuring a measured optical bandwidth of 325 nm and a theoretical spectral resolution of 1.2 nm. We fabricate and test on lithium niobate-on-insulator to take full advantage of the platform, namely electro-optic modulation, broad transparency range and the low optical loss achieved thanks to matured fabrication techniques. We use the electro-optic effect and develop innovative layouts to overcome the undersampling limitations and improve the spectral resolution, thus providing a framework to enhance the performance of all devices sharing the same working principle. With our work, we add another important element to the portfolio of integrated lithium-niobate optical devices as our spectrometer can be combined with multiple other building blocks to realise functional, monolithic and compact photonic integrated circuits.
Si/SiGe QuBus for single electron information-processing devices with memory and micron-scale connectivity function
Authors: Xue Ran , Beer Max , Seidler Inga , Humpohl Simon , Tu Jhih-Sian , Trellenkamp Stefan , Struck Tom , Bluhm Hendrik , Schreiber Lars R.
Published: March 2024

The connectivity within single carrier information-processing devices requires transport and storage of single charge quanta. Single electrons have been adiabatically transported while confined to a moving quantum dot in short, all-electrical Si/SiGe shuttle device, called quantum bus (QuBus). Here we show a QuBus spanning a length of 10 μm and operated by only six simply-tunable voltage pulses. We introduce a characterization method, called shuttle-tomography, to benchmark the potential imperfections and local shuttle-fidelity of the QuBus. The fidelity of the single-electron shuttle across the full device and back (a total distance of 19 μm) is (99.7 ± 0.3) %. Using the QuBus, we position and detect up to 34 electrons and initialize a register of 34 quantum dots with arbitrarily chosen patterns of zero and single-electrons. The simple operation signals, compatibility with industry fabrication and low spin-environment-interaction in 28Si/SiGe, promises long-range spin-conserving transport of spin qubits for quantum connectivity in quantum computing architectures.
Anomalous and Chern topological waves in hyperbolic networks
Authors: Chen Qiaolu , Zhang Zhe , Qin Haoye , Bossart Aleksi , Yang Yihao , Chen Hongsheng , Fleury Romain
Published: March 2024

Hyperbolic lattices are a new type of synthetic materials based on regular tessellations in non-Euclidean spaces with constant negative curvature. While so far, there has been several theoretical investigations of hyperbolic topological media, experimental work has been limited to time-reversal invariant systems made of coupled discrete resonances, leaving the more interesting case of robust, unidirectional edge wave transport completely unobserved. Here, we report a non-reciprocal hyperbolic network that exhibits both Chern and anomalous chiral edge modes, and implement it on a planar microwave platform. We experimentally evidence the unidirectional character of the topological edge modes by direct field mapping. We demonstrate the topological origin of these hyperbolic chiral edge modes by an explicit topological invariant measurement, performed from external probes. Our work extends the reach of topological wave physics by allowing for backscattering-immune transport in materials with synthetic non-Euclidean behavior.
Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
Authors: Pal Ankita , Andersson Dan I.
Published: March 2024

Antibiotic heteroresistance is a phenotype in which a susceptible bacterial population includes a small subpopulation of cells that are more resistant than the main population. Such resistance can arise by tandem amplification of DNA regions containing resistance genes that in single copy are not sufficient to confer resistance. However, tandem amplifications often carry fitness costs, manifested as reduced growth rates. Here, we investigated if and how these fitness costs can be genetically ameliorated. We evolved four clinical isolates of three bacterial species that show heteroresistance to tobramycin, gentamicin and tetracyclines at increasing antibiotic concentrations above the minimal inhibitory concentration (MIC) of the main susceptible population. This led to a rapid enrichment of resistant cells with up to an 80-fold increase in the resistance gene copy number, an increased MIC, and severely reduced growth rates. When further evolved in the presence of antibiotic, these strains acquired compensatory resistance mutations and showed a reduction in copy number while maintaining high-level resistance. A deterministic model indicated that the loss of amplified units was driven mainly by their fitness costs and that the compensatory mutations did not affect the loss rate of the gene amplifications. Our findings suggest that heteroresistance mediated by copy number changes can facilitate and precede the evolution towards stable resistance.
Trade-offs in land-based carbon removal measures under 1.5 °C and 2 °C futures
Authors: Zhao Xin , Mignone Bryan K. , Wise Marshall A. , McJeon Haewon C.
Published: March 2024

Land-based carbon removals, specifically afforestation/reforestation and bioenergy with carbon capture and storage (BECCS), vary widely in 1.5 °C and 2 °C scenarios generated by integrated assessment models. Because underlying drivers are difficult to assess, we use a well-known integrated assessment model, GCAM, to demonstrate that land-based carbon removals are sensitive to the strength and scope of land-based mitigation policies. We find that while cumulative afforestation/reforestation and BECCS deployment are inversely related, they are both typically part of cost-effective mitigation pathways, with forestry options deployed earlier. While the CO2 removal intensity (removal per unit land) of BECCS is typically higher than afforestation/reforestation over long time horizons, the BECCS removal intensity is sensitive to feedstock and technology choices whereas the afforestation/reforestation removal intensity is sensitive to land policy choices. Finally, we find a generally positive relationship between agricultural prices and removal effectiveness of land-based mitigation, suggesting that some trade-offs may be difficult to avoid.
Electrothermally controlled origami fabricated by 4D printing of continuous fiber-reinforced composites
Authors: Wang Yaohui , Ye Haitao , He Jian , Ge Qi , Xiong Yi
Published: March 2024

Active origami capable of precise deployment control, enabling on-demand modulation of its properties, is highly desirable in multi-scenario and multi-task applications. While 4D printing with shape memory composites holds great promise to realize such active origami, it still faces challenges such as low load-bearing capacity and limited transformable states. Here, we report a fabrication-design-actuation method of precisely controlled electrothermal origami with excellent mechanical performance and spatiotemporal controllability, utilizing 4D printing of continuous fiber-reinforced composites. The incorporation of continuous carbon fibers empowers electrothermal origami with a controllable actuation process via Joule heating, increased actuation force through improved heat conduction, and enhanced mechanical properties as a result of reinforcement. By modeling the multi-physical and highly nonlinear deploying process, we attain precise control over the active origami, allowing it to be reconfigured and locked into any desired configuration by manipulating activation parameters. Furthermore, we showcase the versatility of electrothermal origami by constructing reconfigurable robots, customizable architected materials, and programmable wings, which broadens the practical engineering applications of origami.
Excitonic Mott insulator in a Bose-Fermi-Hubbard system of moiré WS2/WSe2 heterobilayer
Authors: Gao Beini , Suárez-Forero Daniel G. , Sarkar Supratik , Huang Tsung-Sheng , Session Deric , Mehrabad Mahmoud Jalali , Ni Ruihao , Xie Ming , Upadhyay Pranshoo , Vannucci Jonathan , Mittal Sunil , Watanabe Kenji , Taniguchi Takashi , Imamoglu Atac , Zhou You , Hafezi Mohammad
Published: March 2024

Understanding the Hubbard model is crucial for investigating various quantum many-body states and its fermionic and bosonic versions have been largely realized separately. Recently, transition metal dichalcogenides heterobilayers have emerged as a promising platform for simulating the rich physics of the Hubbard model. In this work, we explore the interplay between fermionic and bosonic populations, using a WS2/WSe2 heterobilayer device that hosts this hybrid particle density. We independently tune the fermionic and bosonic populations by electronic doping and optical injection of electron-hole pairs, respectively. This enables us to form strongly interacting excitons that are manifested in a large energy gap in the photoluminescence spectrum. The incompressibility of excitons is further corroborated by observing a suppression of exciton diffusion with increasing pump intensity, as opposed to the expected behavior of a weakly interacting gas of bosons, suggesting the formation of a bosonic Mott insulator. We explain our observations using a two-band model including phase space filling. Our system provides a controllable approach to the exploration of quantum many-body effects in the generalized Bose-Fermi-Hubbard model.
Observation of vortex-string chiral modes in metamaterials
Authors: Ma Jingwen , Jia Ding , Zhang Li , Guan Yi-jun , Ge Yong , Sun Hong-xiang , Yuan Shou-qi , Chen Hongsheng , Yang Yihao , Zhang Xiang
Published: March 2024

As hypothetical topological defects in the geometry of spacetime, vortex strings could have played many roles in cosmology, and their distinct features can provide observable clues about the early universe’s evolution. A key feature of vortex strings is that they can interact with Weyl fermionic modes and support massless chiral-anomaly states along strings. To date, despite many attempts to detect vortex strings in astrophysics or to emulate them in artificially created systems, observation of these vortex-string chiral modes remains experimentally elusive. Here we report experimental observations of vortex-string chiral modes using a metamaterial system. This is implemented by inhomogeneous perturbation of Yang-monopole phononic metamaterials. The measured linear dispersion and modal profiles confirm the existence of topological modes bound to and propagating along the string with the chiral anomaly. Our work provides a platform for studying diverse cosmic topological defects in astrophysics and offers applications as topological fibres in communication techniques.
Higher order gaps in the renormalized band structure of doubly aligned hBN/bilayer graphene moiré superlattice
Authors: Jat Mohit Kumar , Tiwari Priya , Bajaj Robin , Shitut Ishita , Mandal Shinjan , Watanabe Kenji , Taniguchi Takashi , Krishnamurthy H. R. , Jain Manish , Bid Aveek
Published: March 2024

This paper presents our findings on the recursive band gap engineering of chiral fermions in bilayer graphene doubly aligned with hBN. Using two interfering moiré potentials, we generate a supermoiré pattern that renormalizes the electronic bands of the pristine bilayer graphene, resulting in higher order fractal gaps even at very low energies. These Bragg gaps can be mapped using a unique linear combination of periodic areas within the system. To validate our findings, we use electronic transport measurements to identify the position of these gaps as a function of the carrier density. We establish their agreement with the predicted carrier densities and corresponding quantum numbers obtained using the continuum model. Our study provides strong evidence of the quantization of the momentum-space area of quasi-Brillouin zones in a minimally incommensurate lattice. It fills important gaps in the understanding of band structure engineering of Dirac fermions with a doubly periodic superlattice spinor potential.
Ultra-compact exciton polariton modulator based on van der Waals semiconductors
Authors: Lee Seong Won , Lee Jong Seok , Choi Woo Hun , Choi Daegwang , Gong Su-Hyun
Published: March 2024

With the rapid emergence of artificial intelligence (AI) technology and the exponential growth in data generation, there is an increasing demand for high-performance and highly integratable optical modulators. In this work, we present an ultra-compact exciton-polariton Mach–Zehnder (MZ) modulator based on WS2 multilayers. The guided exciton-polariton modes arise in an ultrathin WS2 waveguide due to the strong excitonic resonance. By locally exciting excitons using a modulation laser in one arm of the MZ modulator, we induce changes in the effective refractive index of the polariton mode, resulting in modulation of transmitted intensity. Remarkably, we achieve a maximum modulation of −6.20 dB with an ultra-short modulation length of 2 μm. Our MZ modulator boasts an ultra-compact footprint area of ~30 μm² and a thin thickness of 18 nm. Our findings present new opportunities for the advancement of highly integrated and efficient photonic devices utilizing van der Waals materials.
Tailoring d-band center of high-valent metal-oxo species for pollutant removal via complete polymerization
Authors: Liu Hong-Zhi , Shu Xiao-Xuan , Huang Mingjie , Wu Bing-Bing , Chen Jie-Jie , Wang Xi-Sheng , Li Hui-Lin , Yu Han-Qing
Published: March 2024

Polymerization-driven removal of pollutants in advanced oxidation processes (AOPs) offers a sustainable way for the simultaneous achievement of contamination abatement and resource recovery, supporting a low-carbon water purification approach. However, regulating such a process remains a great challenge due to the insufficient microscopic understanding of electronic structure-dependent reaction mechanisms. Herein, this work probes the origin of catalytic pollutant polymerization using a series of transition metal (Cu, Ni, Co, and Fe) single-atom catalysts and identifies the d-band center of active site as the key driver for polymerization transfer of pollutants. The high-valent metal-oxo species, produced via peroxymonosulfate activation, are found to trigger the pollutant removal via polymerization transfer. Phenoxyl radicals, identified by the innovative spin-trapping and quenching approaches, act as the key intermediate in the polymerization reactions. More importantly, the oxidation capacity of high-valent metal-oxo species can be facilely tuned by regulating their binding strength for peroxymonosulfate through d-band center modulation. A 100% polymerization transfer ratio is achieved by lowering the d-band center. This work presents a paradigm to dynamically modulate the electronic structure of high-valent metal-oxo species and optimize pollutant removal from wastewater via polymerization.
Flexible and wearable battery-free backscatter wireless communication system for colour imaging
Authors: Zhan Jun-Lin , Lu Wei-Bing , Ding Cong , Sun Zhen , Yu Bu-Yun , Ju Lu , Liang Xin-Hua , Chen Zhao-Min , Chen Hao , Jia Yong-Hao , Liu Zhen-Guo , Cui Tie-Jun
Published: March 2024

Wireless imaging, equipped with ultralow power wireless communications and energy harvesting (EH) capabilities, have emerged as battery-free and sustainable solutions. However, the challenge of implementing wireless colour imaging in wearable applications remains, primarily due to high power demands and the need to balance energy harvesting efficiency with device compactness. To address these issues, we propose a flexible and wearable battery-free backscatter wireless communication system specially designed for colour imaging. The system features a hybrid RF-solar EH array that efficiently harvests energy from both ambient RF and visible light energy, ensuring continuous operation in diverse environments. Moreover, flexible materials allow the working system to conform to the human body, ensuring comfort, user-friendliness, and safety. Furthermore, a compact design utilizing a shared-aperture antenna array for simultaneous wireless information and power transfer (SWIPT), coupled with an optically transparent stacked structure. This design not only optimizes space but also maintains the performance of both communication and EH processes. The proposed flexible and wearable systems for colour imaging would have potentially applications in environmental monitoring, object detection, and law enforcement recording. This approach demonstrates a sustainable and practical solution for the next generation of wearable, power-demanding devices.
Deformable micro-supercapacitor fabricated via laser ablation patterning of Graphene/liquid metal
Authors: Kim Keon-Woo , Park Seong Ju , Park Su-Jeong , Kim Inae , Park Bomi , Kim Se Hyun , Jeong Unyong , Kim Jin Kon , Yang Chanwoo
Published: March 2024

Deformable and miniaturized energy storage devices are essential for powering soft electronics. Herein, we fabricate deformable micro supercapacitors (MSCs) based on eutectic gallium-indium liquid metal (EGaIn) current collectors with integrated graphene. The well-define interdigitated electrode patterning with controlled gap is successfully realized by using the laser ablation because of a strong laser absorption of graphene and EGaIn. By judicious control of gap size between neighboring interdigitated electrodes and mass loading of graphene, we achieve a high areal capacitance (1336 µF cm−2) with reliable rate performance. In addition, owing to the intrinsic liquid characteristics of EGaIn current collector, the areal capacitance of fabricated MSC retains 90% of original value even after repetitive folding and 20% stretching up to 1000 cycles. Finally, we successfully integrate deformable MSC with a commercial light-emitting diode to demonstrate the feasibility of MSC as a deformable power source. The fabricated MSCs operate stably under various mechanical deformations, including stretching, folding, twisting, and wrinkling.