bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of two-stage energy input on enhancing the flotation process of high-ash coal slime
Authors: Wang Xing , Han Youli , Zhu Jinbo , Liu Lingyun , Wang Hongyang , Lin Zhiyong , Xia Shuwei , Wang Po
Published: June 2024

To solve the mismatch problems of nonlinear changes of coal slurry properties and energy input during the continuous flotation process, we used a two-stage energy input method to promote the efficient recovery of clean coal and achieve maximized benefits. Results showed that the flotation rate constant increased with the increase in stirring speed and reached its maximum value of 0.0271 s-1 when the stirring speed increased to 1200 r/min under a single energy input, with a maximum combustible recovery of 74.35%. However, the short-term flotation results within 40 s showed that the combustible recovery increased with stirring speed and reached its maximum value of 50.19% at 1500 r/min. The stirring speed was set at 1800 r/min for a fast flotation period and 2400 r/min for an enhanced separation period, which could achieve a maximum combustible recovery of 89.21%. Furthermore, the adsorption density of the collector was optimized, exceeding that achieved under single-stage energy input. The flotation process could be optimized by two-stage energy input. Coarse coal particles were preferentially floated by low-speed stirring in the initial fast selection period. Fine coal particles were further separated during the enhanced separation period under the action of high-speed shear. Two-stage energy input could significantly improve the combustible recovery of the overall flotation of coal slime.
Global Climate Resources and Climate Change for Beach Tourism (1950‐2019)
Authors: Ma Siyao , Craig Christopher A.
Published: June 2024

Climate is a primary determinant of tourism and recreational decisions. According to climate resource perspective–the study’s theoretical perspective–climate resources are meteorological variables of confirmable consequence to firm performance. Climate resources can
be quantified using climate indices, or equations that variably weight meteorological variables that influence tourist decisions. To date, researchers have yet to calculate climate resources at the global scale using an index formulated for beach tourism, a subsector of marine tourism. We
address this research gap, calculating the Holiday Climate Index (HCI)-beach globally from 1950 to 2019. The HCI-beach was formulated based on beach tourist surveys, an extensive literature review, and has been validated as the best‐fit index for beach tourism. Study findings (1) quantify
ideal and unacceptable conditions for beach tourism globally, and (2) identify geographies with significant HCI‐beach changes over the span of 70 years (i.e., climate change). Findings contribute to the resource heterogeneity of climate resource perspective.
Layanan KOBE “Konsultasi Belajar” Untuk Meningkatkan Literasi Baca Tulis Siswa Sekolah Dasar
Authors: Darni Ni Komang Ari Rahayu
Published: June 2024

The urgency of this research is to find out the benefits of KOBE services in improving students' reading and writing literacy at SD Negeri 4 Patas, Buleleng Regency. This research uses a qualitative approach with a case study design. This research will combine two traditions of qualitative research, namely phenomenology and instrumental case studies. In this research, data analysis is inductive, conducted through data collection, data analysis, reducing, presenting sorted data, and drawing conclusions or verifying findings. The research data sources involved primary data sources, consisting of principals, teachers, students, as well as other parties related to the problem being studied. The results showed that literacy skills are low at SD Negeri 4 Patas, with only 34% of students reaching the AKM standard. The causes include low reading interest, limited reading media, and reading difficulties. The proposed solution is a “Learning Consultation” (KOBE) service to improve students' literacy and create a productive learning atmosphere.
Promoting Equity in Education: Lessons from Ghanaian Education Policy Texts
Authors: Addai Yaa Serwaa , Adzahlie-Mensah Vincent
Published: June 2024

This paper addresses the issue of equity in education by exploring how Ghanaian education policy texts foregrounds equity and address inequities. We used a critical pedagogy lens and equity theory to highlight how Ghanaian teacher education policy, national teacher standards and assessment policies promote equity and situates it at the centre of curriculum framework, classroom teaching and learning as well as assessment. From our analyses of policy texts, Ghanaian school classrooms are to be equitable and become places where students’ uniqueness is recognised, respected and supported. The pedagogic relations and student-student interactions are to promote equity. However, we highlight gaps in knowledge about equity literacy among teachers; how they understand equity in the classroom; how teachers actually promote equity in classroom and the challenges they face in so doing; as well as how learners experience equity in the classroom. Therefore, we argued that there the need for research into equity literacy among teachers, how they promote equity in the classroom and how students experience it. This necessitates research into how teachers promote equity at the school site in terms of teacher-student and student-student interactions.
El Aprendizaje Basado en Problemas: Competencias Adquiridas en el Internado de Medicina
Authors: Romero Acaro Richard Fernando , Salinas Torres Mayra Liliana
Published: June 2024

El aprendizaje basado en problemas (ABP) se ha constituido actualmente en un modelo educativo que ha cambiado el paradigma del proceso enseñanza-aprendizaje, siendo relevante para la formación profesional de estudiantes autocríticos y en capacidad de enfrentar las diferentes problemáticas que se les presente. Con este trabajo, se dio respuesta a la pregunta, ¿Cómo contribuye la metodología ABP en la adquisición de competencias específicas en los estudiantes de internado rotativo del Hospital Isidro Ayora?  Los objetivos del proyecto fueron identificar las competencias específicas que los internos de medicina consideran haber adquirido y explorar las experiencias de los internos de medicina con respecto al ABP. El proceso metodológico en el que se recoge la opinión de los estudiantes de medicina se realizó mediante la aplicación de un cuestionario, centrado en el análisis concreto de las competencias adquiridas con el ABP y la entrevista por grupo focal para explorar sus experiencias con esta metodología. Los resultados obtenidos demostraron que la aplicación del ABP, permite adquirir varias competencias que son necesarias para un correcto desenvolvimiento laboral en medicina. Así mismo se pudo concluir que el ABP es una piedra fundamental en la formación de los médicos.
Tourism Resources Development Policy in Increasing Regional Original Revenue in Bulukumba Regency
Authors: Syamsul Bahri Andi Iqra , Usman Jaelan , Fatmawati Fatmawati
Published: June 2024

Tourism as a core economy, is now a common goal, not only for all Kemenpar personnel, but also for the entire Indonesian nation. The research was conducted at the Bulukumba Regency Youth and Sports Tourism Office, this type of research is qualitative. This research data was obtained through observation, interviews, documentation, and media review. Data validity is done through tringulation of sources, techniques, and time and then analyzed through data reduction techniques, data presentation and conclusion drawing, and assisted by data analysis tools namely Nvivo 12 plus software. The results confirmed that tourism development in Bulukumba Regency has shown significant progress. The success of tourism development policy in the region can be measured by the effectiveness of communication in its implementation, where information is successfully delivered to all stakeholders with high consistency. The available resources have also been sufficient to cover various aspects, including human, financial, and material resources. However, there are shortcomings that still need attention, especially in the aspect of information resources, where there is still a need for improvement and provision of adequate information resources to support further tourism development.
Success Rate of Frozen Embryo Transfer through Assisted Hatching Laser Method and Tyrode Acid Chemical Method in Day 3 and 5 Embryos
Authors: Hartini Prastuti Dwi , Lisa Lucy , Nurcahya Harini , Irmansyah Frizar , Gunarwati Deka Putri
Published: June 2024

Repeated implantation failures in IVF, aging in women and vitrification at low temperatures cause the embryonic zona pellucida to harden.Technique assisted hatching (AH) laser and chemical methods of tyrode acid can help the process hatching in embryos in improving implantation. The purpose of this study is to determine the relationship between pregnancy success through AH laser method and chemical method of tyrode acid at the embryonic stage day to-3 (D3) and day to-5 (D5) on Frozen Embryo Transfer (FET). The study used a retrospective cohort with a population of 95 patients using AH laser method and 36 patients with tyrode acid chemistry. The results showed the incidence of pregnancy in laser treatment in 27 patients (28.4%) and 14 patients (38.9%) in chemical treatment. Data analyzed by statistical tests Chi-square with a 95% confidence degree and a p< value of 0.05. Exist The relationship between the incidence of pregnancy FET D3 and FET D5 laser treatment, but in chemical treatment no significant difference was found. Logistic regression modeling tests show the chemical method FET D5 has a greater chance of pregnancy of 0.277 than FET D3, will but insignificant with a p-value of >0.05, while the FET D5 laser stage method has a chance of 0.143 significantly higher than FET D3 with a p-value of <0.05.
Study of Some Immunologic Parameters in Aborted Women Infected with Toxoplasma Gondii
Authors: Husham Hiba Aeiad , Al-Mussawi Kawther A. M.
Published: June 2024

The demographic data of the patients was collected using a pre-designed questionnaire that included information on age and exposure to animals. Written permission was obtained from all participants in this research.The research was conducted in Karbala Maternity and Pediatric Hospital as well as other private labs in Kerbala city, Iraq, from November 2022 to May 2023. The blood samples underwent centrifugation, and the levels of serum IgM, IgG, interleukin-27 (IL-27), and Monocyte Chemoattractant Protein-1 (MCP-1) were measured using the enzyme-linked immunosorbent assay (ELISA) technique. The findings indicated that a total of 53 female individuals had abortion as a direct consequence of toxoplasmosis infection. The age group with the greatest incidence rate (56.6%) of toxoplasmosis was 18-26 years, whereas 79.2% of the patients were found to have had contact with animals. The blood immunoglobulin level analysis revealed that 98.1% of patients exhibited positive IgG findings, while 1.9% tested positive for IgM. In contrast, all healthy women in the control group tested negative for both IgM and IgG. The study found that women infected with toxoplasmosis had significantly higher levels of serum IL-27 (645.95 pg/ml) compared to the control group (88.26 pg/ml). Similarly, the infected women had significantly higher levels of MCP-1 (272.20 pg/ml) compared to the control group (48.83 pg/ml). These differences in interleukin levels were highly significant (P<0.0001). The present investigation indicates that women with recurrent abortion who were infected with T. gondii had elevated levels of IgG, IL-27, and MCP-1.
PENGUKURAN BEBAN KERJA PEKERJA DI UD. BINTANG JAYA MANDIRI MENGUNAKAN CVL DAN NASA-TLX
Authors: Puyuhiyo Zulqarnain , Wolok Eduart , Lahay Idham Halid
Published: June 2024

Abstract: Measuring Workload of Workers at UD. Bintang Jaya Mandiri uses CVL and NASA-TLX
The amount of physical and mental load depends on the level of difficulty of each activity, causing different workloads. The method for measuring physical workload uses the %CVL (Cardiovascular Load) method, while the method for measuring mental load uses the NASA-TLX (National Aeronautics and Space Administration Task Load Index) method. Calculation results from workers at UD. Bintang Kaya Mandiri used the %CVL method in shift I. The values ​​obtained were classified as "Medium" (30% to ≤ 60%) "Required improvement but not urgent" for 18 people and classified as "Low" (≤ 30%) "There is no fatigue in workers" as many as 2 people, while shift II scores obtained were classified as "Medium" (30% to ≤ 60%) "Required improvement but not urgent" as many as 16 people and classified as "Low" (≤ 30%) "There is no fatigue among workers ” as many as 4 people. Measuring mental load using the NASA-TLX method in shift I, the scores obtained were classified as "Quite High" (30-49) by 1 person and classified as "High" (50-79) by 19 people, while in shift II the scores obtained were classified as " Fairly High” (30-49) as many as 3 people and classified as “High” (50-79) as many as 17 people.
The Principles of Legal Certainty for Land Rights After Natural Disaster in Indonesia
Authors: Rachmah Andriana , Sudiro Amad
Published: June 2024

This paper explores the principles of legal certainty for community land rights in the subsequent to the occurrence of catastrophic natural events in Indonesia, it probes into the intricacies of land ownership and the challenges faced by communities when their lands are devastated by natural calamities. The research scrutinizes the jurisprudential structure of Indonesia, its efficacy, and the lacunae present in the protection of property rights amidst such calamities. It additionally deliberates on the functions of governmental and non-governmental entities, and international bodies in ensuring legal certainty for affected communities. The paper concludes with recommendations for policy changes and legal reforms to augment the safeguarding of communal property rights in the advent of catastrophic natural events. This research contributes to the discourse on land rights and legal certainty, providing valuable insights for policymakers, legal practitioners, and disaster management agencies.
Legal Protection for Good Faith Buyers in Land Sale and Purchase Transactions (Study of Decision Number 3915 K/Pdt/2022)
Authors: Irene Irene , Tjempaka Tjempaka
Published: June 2024

Land is an essential need for humans. Because it is used to fulfill basic human needs such as shelter and food production. Land is used to meet human needs. Soil is an important part of human life. What needs to be understood is that land is a place to live, as a means of residence and humans obtain land by managing and utilizing land as much as possible. In the utilization and acquisition of land, of course there is government involvement and authority. In writing this thesis, the author raised a dispute case originating from the Supreme Court Court Decision Case Number 3915 K/Pdt/2022. Initially, the Plaintiff (PT Grow Selamat Makmur) and the Defendant (PT Surya Cipta Khatulistiwa) were involved in a sale and purchase agreement for 24 plots of land in Bogor Regency through Deed No.05 dated 16 July 2018. These lands had title certificates, including Title Certificates. Building Use and Use Rights Certificates, with details of 15 Building Use Rights Certificates and 9 Use Rights Certificates. In this agreement, it was agreed that the land price would be Rp. 550,000/m2, as well as payment procedures which reach a total of Rp. 119,560,000,000, although the land area has not been re-measured by the local Land Agency, the Buyer (Plaintiff) has paid the price according to the agreement. Based on the problems studied, the type of research is normative legal research, where law is conceptualized as what is written in statutory regulations (law in books) or law is conceptualized as rules or norms which are benchmarks for human behavior that is considered appropriate. Normative legal research refers to legal norms contained in regulations or laws related to Supreme Court Decision No. 3915 K/Pdt/2022.
Pengaruh Key Opinion Leader (KOL) Terhadap Jumlah Followers Instagram Tropikana Waterpark
Authors: Hardian Valent Sausan Hadipura , Kholik Abdul , Fatimah Anggun Nadia
Published: June 2024

Penelitian ini bertujuan untuk menguji pengaruh Key Opinion Leader (KOL) terhadap jumlah followers Instagram Tropikana Waterpark dalam konteks teknologi informasi dan sistem informasi. Instagram merupakan platform media sosial yang populer dengan pengguna aktif yang terus meningkat, serta memiliki potensi sebagai sarana pemasaran yang efektif melalui implementasi metode pengambilan keputusan berbasis data. Jumlah followers di Instagram menjadi indikator keberhasilan akun dan strategi pemasaran, serta memiliki peran penting dalam meningkatkan exposure, keterlibatan, dan kredibilitas suatu akun. Penelitian ini menggunakan metode kuantitatif dengan melibatkan data followers Instagram Tropikana Waterpark dan jumlah pengikut KOL yang terkait dengan akun tersebut. Data dianalisis menggunakan teknik regresi untuk menguji hubungan antara KOL dan jumlah followers. Hasil penelitian menunjukkan adanya pengaruh positif yang signifikan antara KOL dan jumlah followers Instagram Tropikana Waterpark. KOL yang memiliki jumlah followers yang besar dan kemampuan mempengaruhi keputusan dan tindakan followers-nya dapat membantu meningkatkan jumlah followers akun Instagram Tropikana Waterpark. Temuan ini memiliki implikasi penting bagi pengembangan aplikasi teknologi informasi dalam strategi pemasaran digital, terutama dalam memanfaatkan analisis data untuk mengoptimalkan engagement dan peningkatan jumlah followers. Penelitian ini memberikan kontribusi dalam pemahaman tentang pengaruh KOL dalam konteks media sosial, khususnya Instagram, serta menyoroti pentingnya kerja sama dengan KOL dalam strategi pemasaran yang didukung oleh teknologi informasi. Hasil penelitian ini dapat menjadi acuan bagi perusahaan atau akun bisnis lainnya yang ingin memanfaatkan potensi Instagram sebagai platform pemasaran yang efektif melalui kolaborasi dengan KOL, serta menerapkan teknologi informasi untuk meningkatkan efektivitas kampanye pemasaran mereka.
Analisis Pemberian Restitusi kepada Keluarga Korban Kekerasan Fisik yang Menyebabkan Kematian Sebagai Bentuk Keadilan Hukum
Authors: Anisa Puspitasari  , Rasji Rasji
Published: June 2024

Physical violence refers to any act of aggression directed at another individual by a person using their own body that results in harm or even death to the target of the aggression. The Cibadak District Court Decision Number 85/Pid.B/2022, which explains that Jana Sahroni committed an act of physical violence that resulted in the victim's death, is the focus of this legal research. The judge sentenced Sahroni to seven (seven) years in prison without imposing any restitution to be given to the victim's family, who was left behind. the extent of the perpetrator's legal liability for using physical force that results in death and if the victim's family can receive compensation. This legal writing, which is normative juridical research, focuses on comprehending laws and regulations and evaluating the legal sources that were employed through a literature review. As a result, a decision will eventually be made about the legalisation of violent crimes that result in death as well as the payment of compensation to the victim's family.
Family Structure: A Perspective of Classroom Advisers
Authors: C. Alcantara Ritchell
Published: June 2024

This study explored the perspectives of classroom teachers on their students' behavior and family structures. Using qualitative phenomenological approach, I purposively engaged in the in-depth interview 14 class advisers of Antonio O. Floirendo Elementary School II. The data which I had recorded during the interview were transcribed, clustered according to themes, presented in matrices, and discussed in response to the objectives of investigation. The results revealed that as to the perspectives of the classroom advisers on the family structure of their students which they perceive to have impacted or affected their classroom behavior, both nuclear and non-nuclear family structures have some positive and negative effects on their students’ classroom behavior. As to the coping mechanism to address the negative effects of family structures on their students’ classroom behaviors, the advisers have used some systems such as, building relationships and communication, establishing classroom rules, encouraging positive behavior and positive classroom climate, and flexibility. As regards the educational management, I have seen from the perspectives of the advisers the vitality of parental involvement, open communication, provision of sense of belongingness, conduct of regular conferences on peer mentoring programs or counseling services to students, parents/ guardians and teachers, provision of resources and support for disadvantaged students and their families through partnership with school communities and local government units.
How Remote Work is Transforming Urban Real Estate - A Push towards Community Living
Authors: Pattnaik Samyak
Published: June 2024

This paper conducts a comprehensive analysis of the impacts of remote work on both residential and commercial real estate sectors, examining changes in demand, property values, and urban development patterns. Through a thorough literature review and empirical analysis, the study highlights significant trends such as the preference for suburban living, the decline in traditional office space demand, and the rise of community-focused living arrangements. The study also offers strategic recommendations for urban planners, real estate stakeholders, policymakers, and business leaders to navigate these changes effectively. It underscores the importance of flexibility, sustainability, and inclusivity in shaping the future of urban development in an era of remote work.
Making and Assessing an Antibacterial Cream with Dalbergia Sissoo Leaf Extract
Authors: Pukale Tushar , More Swapnali , Mulla Sujan , Shaikh Subhan , Maharnawar Sonali , Ghadge Vishal
Published: June 2024

Medicinal plants are still a valuable therapeutic resource for treating human illnesses. The plant Dalbergia sissoo is important to the health care system and includes several chemical constituents that have particular importance in traditional medical practices. This study's primary goal is to assess the ethanol extracts from D. sissoo leaves' antibacterial activity. Using ethanol, the dried leaves of Dalbergia sissoo are extracted. Additionally, the extract's phytochemical screening was completed. The ethanolic extract was then used to make the herbal antibacterial cream composition. Examine the cream's physical characteristics as well. Using the disc diffusion method with bioassay guidance, the assay was conducted on Staphylococcus aureus. Staphylococcus aureus bacteria, both gram positive (+) and gram negative (-), were utilised to measure the antibacterial activity of the cream.
Embedding secrets in pixels: two-level security through DNA encryption and LSB image steganography
Authors: Benyahia Kadda , Khobzaoui Abdelkader , Benbakreti Soumia
Published: June 2024

Transmitting information via a public channel without unauthorized interception is a major concern that leads to the idea of hiding information using cryptographic techniques or obscuring it in a media using steganography algorithms. This article proposes a two-level security image steganography method, (i) using a DNA sequence, the message to be sent is encrypted, (ii) by applying the least significant bits (LSB) technique, this encrypted message is hidden in an image. This combination of DNA-based cryptography and steganography provides two levels of security that ensures confidential transmission, as demonstrated by the experiments conducted.
Assessing the Effects of the 2023 Turkish Earthquakes on Mental Health in Lebanon: A Cross-sectional Study
Authors: Hojeij Moussa , El Khatib Dalida , Salameh Pascale
Published: June 2024

Background: On the 6 of February 2023, an earthquake registering 7.8 on the Richter Scale hit the South and center of Turkey, as well as the North and West Syria. Subsequently, another seismic event with a magnitude of 7.5 ensued a few hours later. Two weeks later, a new earthquake of 6.4 magnitude shook both countries again. These two events left behind more than 50000 deaths and a lot of damage, both economically and psychologically, which affected the Lebanese population.
Aim: This study evaluates the adverse effects of these earthquakes on the mental health of people in Lebanon.
Methods: This is a cross-sectional study conducted between 6 March, and 23 March 2023, using an online survey. The questionnaire was divided into 4 sections: demographics, the mental health of participants, anxiety before the earthquakes, and anxiety after the earthquakes using the Lebanese Anxiety Scale- to differentiate between healthy and anxious participants.
Results: The study involves 670 Lebanese participants aged 18 or above. Anxiety proportion rose post-earthquakes. Pre-earthquakes, anxiety risk factors included female gender, younger age, Beirut residency, mental health issues, and medication use; these factors also significantly raised anxiety after earthquakes.
Conclusion: This study demonstrates a remarkable escalation in anxiety proportion following the earthquakes. Pre-existing risk factors such as female gender, younger age, Beirut residency, mental health issues, and medication use for symptom relief exhibited a heightened association with anxiety after the tectonic events. These findings deepen the importance of targeted interventions to address the psychological impact of earthquakes on vulnerable populations.
The ‘Mystery’ of Lop Nor: Empire, Geographical ‘Problems’ and Climate Change on the Silk Roads
Authors: FLEETWOOD LACHLAN
Published: June 2024

In the late nineteenth century, rumours of a large lake in Central Asia provided the material for a vexing ‘problem’ in imperial geography. That Lop Nor existed – or at least once had – was indicated by information in Chinese chronicles. However, identifying the lake proved challenging, not least because it did not always appear to have been located in the same place. Attracting romanticised epithets like ‘mysterious’ and ‘wandering’, Lop Nor became an important site for imperial scientific speculations about climatic stability and change. This article considers investigations by Russian, British, Swedish and American geographers (as well as the key roles of Loplyk brokers such as Ördek, who located the ancient city of Loulan that had once graced the shores of the lake and been abandoned in the face of changing habitability). In turn, the article examines the way Lop Nor was bound up in the formation of imperial imaginaries of the ‘Silk Roads’, as well as incorporated by geographers like Peter Kropotkin and Ellsworth Huntington into theories of desiccation and climate change within recent human history. More widely, considering debates over Lop Nor allows for an examination of the role of imperial geographical ‘problems’ in the history of climate sciences and the development of geography as a discipline.
Musculoskeletal Disorders in the Workplace of Physiotherapists: Occupational Risk Factors and Their Role in Prevention and Management: A Systematic Review
Authors: Kotnik Petra , Koprivnik Nataša
Published: June 2024

BACKGROUND: Since musculoskeletal disorders at work (MSDW) are very common among physiotherapists, we must introduce strategies that could help reduce their prevalence. The main objective of this study was to determine the prevalence of MSDW among physiotherapists, which parts of the body are most often affected, what are the ergonomic risk factors for MSDW among physiotherapists and what are strategies to reduce them.
METHODS: In the systematic literature review, involving a total of 2127 physiotherapists, search terms such as occupational musculoskeletal disorders, physiotherapists, and occupational risk factors were used in the SCOPUS (n = 24), MEDLINE (n = 2), ScienceDirect (n = 103), PEDro (n = 0), Cumulative index of the nursing and allied health literature (n = 3), and PubMed (n = 30) databases in February 2024. The search included only original studies published in English, cross-sectional studies published in thepast 10 years, studies that included the prevalence of MSDW, and studies that included risk factors for MSDW. In the end, we included eight studies in the systematic review.
RESULTS: A systematic review of eight studies highlighted the prevalence and risk factors associated with MSDW among physiotherapists. The studies were conducted on samples ranging in size from 75 to 501 individuals and focused on determining the prevalence of MSDW and identifying the associated risk factors. The prevalence rates differ, with the lower back region being the most affected region in all studies (38–68.8%), followed by the neck (10–59.2%) and the shoulder girdle (7–51.7%). Risk factors included back strain, awkward posture, prolonged posture, frequent bending/turning of the trunk, performing manual therapy techniques, patient lifting, repetitive tasks, work environment, and psychosocial issues. Reported coping strategies included changing one’s working posture, improving one’s body mechanics, and taking more breaks during the workday.
CONCLUSION: Our systematic review of the literature revealed a high prevalence of MSDW among physical therapists (up to 92%) and highlighted the urgent need for strategies to mitigate this widespread problem. These findings highlight the multifaceted nature of the etiology of MSDW and point to the interplay of physical demands, ergonomic challenges, and psychological stressors that characterize the profession of a physical therapist.
Studying the Specific (Adaptogenic and Anabolic) Activity of the Supramolecular Complex of 20-Hydroxyecdysone Triacetate with β-Cyclodextrin
Authors: Tuleuov B. I. , Kozhanova M. , Temirgaziyev B. S. , Almagambetov Kairtay , Shaidarov M. Z. , Seidakhmetova R. B. , Drašar P. B. , Adekenov S. M.
Published: June 2024

BACKGROUND: A supramolecular complex of ecdysterone triacetate with β-cyclodextrin (β-CD) was synthesized to obtain new potentially bioactive substances and study the effect of bulky pharmacophore-functional groups on the preservation of the specific activity of 20-hydroxyecdysone. The adaptogenic and anabolic activities of the resulting water-soluble inclusion complex were studied. It was established that with the introduction of 3 acyl-pharmacophore groups in the form of encapsulated and hydrophilic supramolecular forms to experimental animals at a dose of 10 mg/kg, the studied complex has anabolic and adaptogenic effects, including increased stress resistance, increased physical endurance, as well as slightly increased weight of the heart and gonads compared to the control.
AIM: Study of the specific activity of the supramolecular complex of ecdysterone 3-acetate with β-CD.
METHODS: During the experimental study of the adaptogenic and anabolic effects of the supramolecular complex of ecdysterone 3-acetate with β-CD, the “open field” and “free swimming” tests were used. Statistical processing of the results was carried out using the Statistica 8 software package. Intergroup differences were assessed using the non-parametric Mann–Whitney U-test. For unpaired related groups, the non-parametric Wilcoxon test was used.
CONCLUSIONS: It has been established that physical activity (swimming) simultaneously has a significant stressor effect on animals and is characterized by an increased supply of glucose into the blood and the breakdown of blood proteins. It was revealed that the supramolecular complex of ecdysterone 3-acetate with β-CD at a dose of 10 mg/kg has anabolic and adaptogenic effects, in particular increased stress resistance and physical endurance of animals, as well as a slightly increased weight of the heart and gonads compared to the control.
A Rare Case of Gastric Metastasis from a Rare Case of Mucosal Malignant Melanoma
Authors: Gashi Zaim , Hamza Astrit , Ukimeri Blerina , Hamza Valon , Zubaku-Rakovic Marigona
Published: June 2024

BACKGROUND: Malignant melanoma (MM) is the deadliest form of skin cancer and the most common carcinoma to metastasize into the gastrointestinal tract (GI). While the jejunum, ileum, colon, and rectum are common gastrointestinal sites of metastasis, metastatic melanoma in the stomach is rare and usually not detected until late in the disease.
CASE PRESENTATION: We report a patient who presented with hematemesis, epigastric pain, and weight loss. In the second esophagogastroduodenoscopy, after 8 months from the first endoscopic assessment, a double ulcerative gastric mass was found, and histopathology confirmed metastatic malignant melanoma. The complete surgical resection of GI metastatic MM in carefully selected patients not only provides symptom control but has also been associated with an increase in overall survival in the absence of other metastatic sites. At present, the overall survival of patients with advanced metastatic MM who have been treated with a combination of immunotherapeutic agents reaches 52% at 5 years.
CONCLUSION: The role of surgery for patients with metastatic involvement of the GI tract with MM is evolving in the era of effective systemic treatments.
Autoinflammatory Diseases: A Review
Authors: An Jason , Marwaha Ashish , Laxer Ronald M.
Published: June 2024

Autoinflammatory disease (AID) is a vast spectrum of disorders characterized by recurrent attacks of sterile inflammation. Since the first cloning of the familial Mediterranean fever gene in 1997, there has been a rapid rate of discovery of new AIDs. As of 2022, there have been 485 inborn errors of immunity documented by the International Union of Immunological Societies, for which many display aspects of autoinflammation. The pathophysiology of AIDs is complex. Although many are caused by rare mutations in genes that govern innate immunity, others are polygenic, where disease expression is thought to be triggered by environmental factors in genetically predisposed hosts. AIDs range in prevalence from common entities like gout to ultrarare monogenic diseases. Whereas AIDs were initially studied in pediatric populations, it is now apparent that they can present in adulthood and even in the elderly. AIDs can be clinically challenging given their rarity, as well as the heterogeneity in presentation and underlying etiology. Although the care of AIDs can span medical disciplines, the rheumatologist often plays a central role given the inflammatory nature of these illnesses. In this review, we explore the current understanding of the pathophysiology of these complex conditions and propose a classification system for AIDs. We place an emphasis on AIDs that present to the adult rheumatologist and discuss important AIDs that can mimic more classic rheumatic diseases such as systemic lupus erythematosus and inflammatory arthritis. Finally, we offer an approach to the clinical assessment, diagnosis, and management of AIDs.
Cardiovascular Events During Pregnancy: Implications for Adverse Pregnancy Outcomes in Individuals With Autoimmune and Rheumatic Diseases
Authors: Dhital Rashmi , Baer Rebecca J. , Bandoli Gretchen , Chambers Christina
Published: June 2024

Objective

This study examined maternal cardiovascular (CV) events relative to adverse pregnancy outcomes among individuals with autoimmune rheumatic diseases (ARDs), primary antiphospholipid syndrome (APS), and those with neither.

Methods

Using a California population-based birth cohort (2005-2020), we identified those with CV events (CVEs), ARDs, and APS through International Classification of Diseases, 9th and 10th revisions, Clinical Modification codes in maternal discharge records. Selected adverse pregnancy outcomes identified from birth certificates were preterm birth (PTB; < 37 weeks' gestation), small-for-gestational-age infants (SGA; birth weight < 10th percentile for age and sex), and a composite of either outcome. Adjusted risk ratios (aRRs) for adverse outcomes and their 95% CIs were calculated.

Results

CVEs occurred more frequently in individuals with ARDs (265 of 19,340 [1.4%]) and primary APS (428 of 7758 [5.5%]) than those without (17,130 of 7,004,334 [0.3%]). The presence vs absence of CVEs was associated with a greater incidence of adverse outcomes in ARD (53.2% vs 26.6%), APS (30.6% vs 20.7%), and non-ARD/APS pregnancies (28.2% vs 15.2%). CVEs were associated with increased risks of SGA in all groups (aRRs 1.2-1.5) and PTB in ARD (aRR 1.6, 95% CI 1.3-2.0) and non-ARD/APS (aRR 1.7, 95% CI 1.7-1.8) pregnancies.

Conclusion

CVEs were associated with modestly increased risks (20-70%) for PTB, SGA, or both across the groups. Notably, > 50% of ARD pregnancies with CVEs experienced adverse pregnancy outcomes. Given that ARD and APS pregnancies have higher (although still low) rates of CVEs and have higher baseline risks of adverse pregnancy outcomes than the general population, the additional burden conferred by CVEs is clinically important.
Violence and precarization of popular housing in Medellín, predatory accumulation as the matrix of urban production
Authors: Corantin Keisha
Published: June 2024

In both North and South, urban renewal and integration policies testify to the growing commodification of popular territories. The scientific literature emphasizes the processes of gentrification and population displacement associated with these dynamics, and questions the violent production of urban space primarily through the actions of the state and private developers. Shedding light on a blind spot in this discussion, this article proposes to study the forms of violence and commodification operating in the informal circuits of urban production and carried out by other actors, by studying an emerging figure in urban production in Latin America: illegal armed groups. In light of the recent capture of the informal land market by criminal organizations in Medellín, the article analyzes how land rights are distributed, legitimized or contested at the local level. We argue that the control of armed groups translates into the violent implementation of land predation that redefines forms of land valorization, access to land, and dwelling in popular neighborhoods, thus establishing predatory accumulation as the matrix of urban production.
D’un engagement à l’échelle communale à un militantisme intercommunal : la professionnalisation d’une association de défense de l’environnement
Authors: Dupuit Elodie
Published: June 2024

L’émergence de l’intercommunalité comme nouvel espace de mobilisation pour les associations locales périurbaines et les effets de ce changement d’échelle sur le fonctionnement des associations, en particulier sur leur professionnalisation, demeurent des sujets peu étudiés. Cet article s’appuie sur une enquête qualitative menée au sein d’une association de défense de l’environnement, située dans le quadrant sud-est du périurbain lyonnais, et qui se mobilise, entre autres, pour le développement du vélo comme moyen de transport quotidien. Dans le périurbain, l’intercommunalité se constitue comme une nouvelle échelle de dialogue et d’action pour les associations locales, à laquelle s’ajoute un ancrage communal, qui reste déterminant dans les actions de l’association. Ce passage à l’échelle intercommunale permet l’embauche de salariés par l’association et entraîne une demande de montée en compétences de l’association.
Le rendement à tout prix. Produire et gérer le coliving bruxellois en contexte de financiarisation
Authors: Casier Charlotte
Published: June 2024

L’article examine comment la financiarisation croissante du marché du logement se matérialise dans les modes de production et de gestion des biens au service d’un rendement élevé et rapide. Mobilisant des méthodes essentiellement qualitatives, il prend comme cas d’étude le coliving bruxellois, niche immobilière qui consiste en la location par des sociétés privées, au sein d’un même bâtiment, de chambres meublées accompagnées d’espaces communs et de services à une clientèle de jeunes expatrié·es. En documentant les stratégies mobilisées à Bruxelles par ces entreprises, la contribution met notamment en lumière les modalités de la financiarisation d’une proportion restreinte mais croissante de l’activité immobilière résidentielle, qui se traduisent par une occupation dense de l’espace, un raccourcissement des délais de production et une réduction du travail de gestion. Elle montre également comment les acteurs de l’immobilier adaptent leurs produits aux contraintes du territoire local pour en tirer profit.
Cohabiter dans une copropriété issue de la vente HLM. Diversification des statuts d’occupation, mixité sociale et rapports de voisinage
Authors: Fol Sylvie , Gali Pauline , Gimat Matthieu , Mondain Marie , Soichet Hortense
Published: June 2024

Un des objectifs de la vente de logements sociaux est de créer de la mixité sociale à l’échelle des immeubles que les organismes HLM vendent à la découpe à des particuliers. Une fois mis en vente, ces immeubles abritent en effet des ménages restés locataires sociaux et des ménages accédants à la propriété, voire des locataires privés, dont le statut social est fréquemment divers. À partir d’une enquête par entretiens réalisée dans trois immeubles franciliens mis en vente à des dates différentes, nous étudions les rapports de voisinage qui découlent de la vente HLM. Nous proposons pour ce faire une typologie des occupants de ces résidences, croisant leurs trajectoires et leurs projets résidentiels, puis nous nous intéressons à la façon dont s’organisent leurs relations de voisinage et la vie collective au sein de l’immeuble. Nous montrons que les statuts d’occupation semblent moins déterminants dans l’organisation des relations de voisinage des résidences enquêtées que dans d’autres immeubles. Le dispositif de vente HLM contribue en effet à limiter la constitution de groupes sociaux autour de ces statuts, qui ne correspondent que partiellement aux positions sociales des ménages ou à leur ancienneté d’emménagement. L’accroissement, au fil du temps passé depuis la mise en vente, de la proportion des propriétaires et locataires privés contribue néanmoins à rendre temporaire la mixité sociale et semble susceptible de marginaliser les ménages restés locataires HLM.
Surveillance for COVID-19 associated mucormycosis: A coordinated effort in prevention and management of rhino-orbital mucormycosis
Authors: Raj Reshma , Rathod Ramya , Bansal Sandeep , Gopal Karunya R , Kothandaraman Kirubakaran , Kaur Harsimran , Chakrabarti Arunaloke
Published: June 2024

Context:

Patients of coronavirus disease 2019 (COVID-19) and factors inducing a diabetogenic state are at increased risk for rhino-orbital mucormycosis (ROM). Efforts to diagnose ROM in its pre-clinical stage would avoid the disease and its consequences.

Aim:

This study aimed to diagnose ROM in the pre-clinical stage of the disease in high-risk patients and treat patients accordingly.

Settings and Design:

This is a single-center, prospective study conducted at a tertiary care center in Northern India in collaboration with departments of Otolaryngology, Internal Medicine, and Mycology.

Materials and Methods:

Fifty-three high-risk patients were enrolled in the study, and all underwent bedside nasal endoscopy with tissue sampling for fungal culture. Patients with suspicious nasal endoscopy findings but negative fungal culture were prescribed oral posaconazole. Those with positive fungal hyphae on nasal endoscopy and culture underwent surgical intervention followed by intravenous amphotericin B, while the remaining patients were kept on follow-up.

Statistical Analysis Used:

Statistical analysis was performed using the Statistical Package for Social Sciences software.

Results:

Among the 53 patients, 13 (24.5%) patients had abnormalities on nasal endoscopy, while the remaining 40 (75.5%) patients had normal nasal mucosal cavities. Seven patients (13.2%) underwent surgery and received intravenous liposomal amphotericin B, while another 7 (13.2%) received oral posaconazole. Thirty-five (66.03%) patients were placed under observation, and 4 (7.5%) patients died due to COVID-19-related illness.

Conclusions:

Nasal endoscopic-guided tissue sampling for fungal culture serves as a valuable surveillance tool for predicting ROM in COVID-19 patients.
Accidental Finding of Tracheal Diverticulum in a Case with Intractable Cough
Authors: Sekar Tamizhan , Agrawal Anand , Singh Kamaljeet , Kharb Sunaina
Published: June 2024

A 43-year-old female presented with complaints of an intractable cough with sputum and fullness in the neck region, which led to irritation and shortness of breath for the last 10 months. The computed tomography (CT) neck was suggestive of small tracheal diverticula seen along the right posterolateral aspect of the trachea, caudal to the level of the thyroid gland, bulging on the posterolateral wall of the trachea on coughing, as visualized through a fibro-optic video bronchoscope. Knowledge about the diagnosis of tracheal diverticulum is essential to avoid overtreatment of an uncontrolled cough and the management of other associated complications in the future.
Unveiling Thrombocytopenia in Drug-resistant Extrapulmonary Tuberculosis: A Comprehensive Review
Authors: Mohan Sanchit , Vaghasia Nupoor , Pujari Vishwanath , Meshram Priti Lokesh
Published: June 2024

ABSTRACT

Immune thrombocytopenia (ITP) is caused because of antibodies to platelets. ITP can be primary or secondary; secondary ITP is usually caused by infections. Tuberculosis (TB) is a rare cause of secondary ITP. Linezolid, despite being the backbone of a drug-resistant TB regimen, is the most common drug to cause thrombocytopenia in this subset of patients. Treatment of ITP requires immunosuppression with pulse steroids and intravenous immunoglobulin which can lead to dissemination of TB and can be catastrophic in patients of drug-resistant TB. Here, we present a case of drug-resistant extrapulmonary TB with ITP, which was managed with low-dose corticosteroids. This case highlights the importance of complete evaluation for the cause of thrombocytopenia and considering ITP as a differential before discontinuing any essential drug in these patients.
Hidden in Plain Sight: Unraveling the Mystery of Hemoptysis
Authors: Ish Pranav , Kumar Naresh , Mohan Sanchit , Kumar Rohit , Malhotra Nipun , Rathi Vidushi , Gupta Nitesh
Published: June 2024

ABSTRACT

Foreign body aspiration is a common cause of hemoptysis. The exact cause may sometimes be hidden and may not be revealed in chest radiology but may eventually come to light with bronchoscopy and may prevent complications.