bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation of Maize (Zea mays L.) Yield Per Harvest Area: Appropriate Methods
Authors: Ngoune Tandzi Liliane , Mutengwa Charles Shelton
Published: December 2019

Standardization of crop yield estimation methods at various levels of farming helps to obtain accurate agricultural statistics as well as assessing the suitability of agricultural practices under various production conditions. The current paper reviews various maize yield estimation methods, taking into account available yield parameters, and it also analyses the yield gap between maize potential and attainable yield. The easiest and more reliable methods of yield estimation are based on yield parameters collected from the field. However, farmer estimation methods are cheaper and faster compared to any other method of yield estimation from farmers’ fields. This paper also elaborates on the importance of the use of more complex methods for yield estimation, such as remote sensing and crop modelling. These complex methods are more accurate and can predict yield before field harvest with less deviation from the exact harvest yield. However, they are very expensive and not efficient for small plots of land (less than 1 ha). Factors that contribute to the gap between potential and actual yield include poor implementation of agricultural policies, strict regulation of fertilizer inputs, vulnerability of smallholder cropping systems to adverse climatic conditions, occurrence of biotic and abiotic constraints, as well as unavailability of seeds and labor.
Dietary Betaine Improves Intestinal Barrier Function and Ameliorates the Impact of Heat Stress in Multiple Vital Organs as Measured by Evans Blue Dye in Broiler Chickens
Authors: Shakeri Majid , Cottrell Jeremy James , Wilkinson Stuart , Zhao Weicheng , Le Hieu Huu , McQuade Rachel , Furness John Barton , Dunshea Frank Rowland
Published: December 2019

In a 2 × 2 factorial design, 60 male Ross-308 broilers were fed either a control or 1 g/kg betaine diet and housed under thermoneutral (TN) or heat stress (HS) conditions. Broilers were acclimated to diets for 1 week under TN (25 °C), then either kept at TN or HS, where the temperature increased 8 h/day at 33 °C and 16 h/day at 25 °C for up to 10 days. Respiration rate (RR) was measured at four time points, and on each of 1, 2, 3, 7 and 10 days of HS, 12 broilers were injected with 0.5 mg/kg of Evans Blue Dye (EBD) solution to quantify regional changes in tissue damage. Betaine was quantified in tissues, and ileal damage was assessed via morphometry and transepithelial resistance (TER). Heat stress elevated RR (p < 0.001) and resulted in reduced villous height (p = 0.009) and TER (p < 0.001), while dietary betaine lowered RR during HS (p < 0.001), increased betaine distribution into tissues, and improved ileal villous height (p < 0.001) and TER (p = 0.006). Heat stress increased EBD in the muscle and kidney of chickens fed the control diet but not in those receiving betaine. Overall, these data indicate that supplemented betaine is distributed to vital organs and the gastrointestinal tract, where it is associated with improved tolerance of HS. Furthermore, EBD markers help reveal the effects of HS on organs dysfunction.
Curcumin Alleviates IUGR Jejunum Damage by Increasing Antioxidant Capacity through Nrf2/Keap1 Pathway in Growing Pigs
Authors: Yan Enfa , Zhang Jiaqi , Han Hongli , Wu Jiamin , Gan Zhending , Wei Chengheng , Zhang Lili , Wang Chao , Wang Tian
Published: December 2019

The purpose of this study was to explore the effects of curcumin on IUGR jejunum damage. A total of 24 IUGR and 12 normal-birth weight (NBW) female crossbred (Duroc × Landrace × Large White) piglets were randomly assigned into three groups at weaning (26 days): IUGR group, NBW group, and IUGR + CUR group, which were fed diets containing 0 mg/kg (NBW), 0 mg/kg (IUGR) and 200 mg/kg (IUGR + CUR) curcumin from 26 to 115 days of age. Results showed that dietary supplementation with 200 mg/kg curcumin significantly increased the total superoxide dismutase (T-SOD) activity and decreased the malondialdehyde (MDA) content in the jejunum of IUGR pigs (p < 0.05). Results of real-time PCR showed that the IUGR + CUR group significantly increased the gene expression of NF-E2-related factor 2 (Nrf2) (p < 0.05), and increased the glutamate-cysteine ligase catalytic subunit (GCLC), superoxide dismutase 1 (SOD1), glutamate-cysteine ligase modifier subunit (GCLM), and NAD(P)H quinone dehydrogenase 1 (NQO1) mRNA expression compared with the IUGR group (p < 0.05). Western blot results showed that dietary supplementation with 200 mg/kg curcumin significantly increased the protein levels of Nrf2 and NQO1. Compared with the IUGR group, pigs in IUGR + CUR group showed significantly decreased the levels of tumor necrosis factor-α (TNFα), interleukin-6 (IL-6), and interferon gamma (IFNγ) (p < 0.05), and increased the interleukin-2 (IL-2) level (p < 0.05). Dietary supplementation with 200 mg/kg curcumin significantly reduced cysteinyl aspartate specific proteinase 3 (caspase3), BCL2-associated X protein (bax), B-cellCLL/lymphoma 2 (bcl2), and heat-shock protein 70 (hsp70) mRNA expression, and increased occludin (ocln) mRNA expression (p < 0.05). In conclusion, dietary supplementation with 200 mg/kg curcumin can alleviate jejunum damage in IUGR growing pigs, through Nrf2/Keap1 pathway.
Human Relationships with Domestic and Other Animals: One Health, One Welfare, One Biology
Authors: Tarazona Ariel M , Ceballos Maria C , Broom Donald M
Published: December 2019

Excessive human population growth, uncontrolled use of natural resources, including deforestation, mining, wasteful systems, biodiversity reduction by agriculture, and damaging climate change affect the existence of all animals, including humans. This discussion is now urgent and people are rethinking their links with the animals we use for clothing, food, work, companionship, entertainment, and research. The concepts of one health, one welfare, and one biology are discussed as a background to driving global change. Nothing should be exploited without considering the ethics of the action and the consequences. This review concerns domesticated animals, including those used for human consumption of meat, eggs, and milk; horses kept for work; and dogs kept for company. Animal welfare includes health, emotional state, and comfort while moving and resting, and is affected by possibilities to show behavior and relationships with others of the same species or with humans. We show some examples of the relations between humans and domesticated animals in the environmental context, including zoonotic diseases, and consider the consequences and the new paradigms resulting from current awareness.
Utilization of Molybdenum Tailings in Concrete Manufacturing: A Review
Authors: Gao Shan , Cui Xiaowei , Zhang Sumei
Published: December 2019

Dealing with mineral tailings is one of the most important topics for solving the environmental problems in the mining industry. Among the techniques converting stacked molybdenum tailings to reusable cleaner products, one of the most effective ones is to use molybdenum tailings in concrete productions. The physical properties including density, microscopic structure and finesse module, and chemical composition of molybdenum tailings are similar with those of natural sand. The radionuclide assessment of molybdenum tailing meets the requirements for using as structural materials. Therefore, Molybdenum tailing is suitable to be used as the replacement of cement and fine aggregates in mortar and concrete. Based on the results of strength and duration performance comparison, the usage of molybdenum tailing as a replacement of natural sand is a more feasible way than that of ground super-fine molybdenum tailings in cement binder. It is feasible to use molybdenum tailings as fine aggregate in the preparation of structural concrete. When the amount of ground super-fine molybdenum tailings replacing cement is less than 10%, it is beneficial to improve the freeze-thaw and carbonization resistance of the concrete.
Game-Theoretic Analysis to Examine How Government Subsidy Policies Affect a Closed-Loop Supply Chain Decision
Authors: Nielsen Izabela Ewa , Majumder Sani , Saha Subrata
Published: December 2019

The pros and cons of government subsidy policies in a closed-loop supply chain (CLSC) setting on optimal pricing, investment decisions in improving product quality, and used product collection under social welfare (SW) optimization goal have not been examined comprehensively. This study compares the outcomes of three government policies under manufacturer-Stackelberg (MS) and retailer-Stackelberg (RS), namely (i) direct subsidy to the consumer, (ii) subsidy to the manufacturer to stimulate used product collection, and (iii) subsidy to the manufacturer to improve product quality. Results demonstrate that the greening level, used product collection, and SW are always higher under the RS game, but the rate of a subsidy granted by the government is always higher under the MS game. Profits for the CLSC members and SW are always higher if the government provides a subsidy directly to the consumer, but productivity of investment in the perspective of the manufacturer or government are less. In a second policy, the government organizations grant a subsidy to the manufacturer to stimulate used product collection, but it does not necessarily yield the desired outcome compared to others. In a third policy, the manufacturer receives a subsidy on a research and development (R&D) investment, but it yields a sub-optimal greening level. This study reveals that the outcomes of subsidy policies can bring benefit to consumers and add a degree of complication for CLSC members; government organizations need to inspect carefully among attributes, mainly product type, power of CLSC members, and investment efficiency for the manufacturer, before implementing any subsidy policies so that it can lead to an environmentally and economically viable outcome.
Augmenting GPS with Geolocated Fiducials to Improve Accuracy for Mobile Robot Applications
Authors: Ross Robert , Hoque Rahinul
Published: December 2019

In recent decades Global Positioning Systems (GPS) have become a ubiquitous tool to support navigation. Traditional GPS has an error in the order of 10–15 m, which is adequate for many applications (e.g., vehicle navigation) but for many robotics applications lacks required accuracy. In this paper we describe a technique, FAGPS (Fiducial Augmented Global Positioning System) to periodically use fiducial markers to lower the GPS drift, and hence for a small time-period have a more accurate GPS determination. We describe results from simulations and from field testing in open-sky environments where horizontal GPS accuracy was improved from a twice the distance root mean square (2DRMS) error of 5.5 m to 2.99 m for a period of up-to 30 min.
Dynamic Behavior of Track Bridge on Serviced Long-Span Road/Railway Bridge
Authors: Choi Jung-Youl , Kim Sun-Hee , Lee Kyu-Yong , Chung Jee-Seung
Published: December 2019

In this study, we predicted the structural behavior of a track-bridge and a bridge based on the expected increases in future train speeds by modeling the Yeongjong Bridge (a part of the Incheon International Airport Expressway in Korea). To verify the train’s safe operation, we performed a three-dimensional (3D) numerical analysis using full-scale bridge modeling. The rail-girder interaction force generated at one end of the direct fixation track of Yeongjong Bridge during train operations was evaluated by taking field measurements of the vertical displacements of the rail and girder at the center and end of a track girder. We further compared our predictions with various field measurements to evaluate the dynamic behavior of the entire Yeongjong Bridge.
Do Grade II Ankle Sprains Have Chronic Effects on the Functional Ability of Ballet Dancers Performing Single-Leg Flat-Foot Stance? An Observational Cross-Sectional Study
Authors: Bodini Bruno Dino , Lucenteforte Giacomo , Serafin Pietro , Barone Lorenzo , Vitale Jacopo A. , Serafin Antonio , Sansone Valerio , Negrini Francesco
Published: December 2019

Ballet dancers have a higher risk than the general population of ankle sprains. Ankle proprioception is of the utmost importance for executing static and dynamic positions typical of ballet dancing. Ankle sprains can create changes in functional ability that may affect ballet performance. The aim of this cross-sectional observational study is to evaluate if non-professional ballet dancers that were previously injured with a grade II ankle sprain carry a long-term stability deficit in ballet specific positions (passé, arabesque) and in single-leg flat-foot stance, thereby affecting ballet performance. We enrolled 22 amateur female ballet dancers, 11 who previously had a grade II ankle injury and 11 who had no history of ankle injury. Stabilometric data (Center of Pressure Speed and Elipse Area) were assessed with the postural electronic multisensory baropodometer in normal, arabesque, and passè positions with both open and closed eyes. Using an unpaired t-test, we compared healthy and pathological feet of the ankle injury group for a standard monopodalic position and two ballet-specific positions. No difference between pathological and healthy feet of non-professional ballet dancers who suffered grade II ankle injury was detected. According to the parameters considered in this study, grade II ankle sprains seem to have a favorable prognosis in the sample that we evaluated.
Error Resilience for Block Compressed Sensing with Multiple-Channel Transmission
Authors: Huang Hsiang-Cheh , Chen Po-Liang , Chang Feng-Cheng
Published: December 2019

Compressed sensing is well known for its superior compression performance, in existing schemes, in lossy compression. Conventional research aims to reach a larger compression ratio at the encoder, with acceptable quality reconstructed images at the decoder. This implies looking for compression performance with error-free transmission between the encoder and the decoder. Besides looking at compression performance, we applied block compressed sensing to digital images for robust transmission. For transmission over lossy channels, error propagation or data loss can be expected, and protection mechanisms for compressed sensing signals are required for guaranteed quality of the reconstructed images. We propose transmitting compressed sensing signals over multiple independent channels for robust transmission. By introducing correlations with multiple-description coding, which is an effective means for error resilient coding, errors induced in the lossy channels can effectively be alleviated. Simulation results presented the applicability and superiority of performance, depicting the effectiveness of protection of compressed sensing signals.
Stress Estimation Using the Acoustoelastic Effect of Surface Waves in Weak Anisotropic Materials
Authors: Jun Jihyun , Shim Young-Dae , Jhang Kyung-Young
Published: December 2019

This paper proposes a novel stress measurement method using the acoustoelastic effect of surface wave to estimate the stress of a homogeneous material plate with orthogonal anisotropy, in which the surface wave velocities are measured in three different directions before and after loading stress. The effectiveness of the proposed method was verified by numerical simulations and experiments. For the simulations, the surface wave velocities in three directions were obtained from a conventional perturbation model for weak anisotropic materials. The simulation results showed that the stress estimation error was less than 3% for an anisotropic rate up to 2% under stress conditions up to 90 MPa. Two specimens were prepared for the experiments, one was almost isotropic and another that had a relatively larger anisotropy rate of 2.6%. Then, the stresses loaded by a tensile test machine were estimated. The results showed good agreement with the given stresses for both specimens. These results confirm that the proposed method can be applied to estimate the surface stress state in anisotropic material plates. The proposed method is simple, practical, and is expected to be useful for monitoring changes of surface stress before and after machining such as the punching or bending of plate.
The Impact of Optogenetics on Regenerative Medicine
Authors: Spagnuolo Gianrico , Genovese Fabio , Fortunato Leonzio , Simeone Michele , Rengo Carlo , Tatullo Marco
Published: December 2019

Optogenetics is a novel strategic field that combines light (opto-) and genetics (genetic) into applications able to control the activity of excitable cells and neuronal circuits. Using genetic manipulation, optogenetics may induce the coding of photosensitive ion channels on specific neurons: this non-invasive technology combines several approaches that allow users to achieve improved optical control and higher resolution. This technology can be applied to optical systems already present in the clinical-diagnostic field, and it has also excellent effects on biological investigations and on therapeutic strategies. Recently, several biomedical applications of optogenetics have been investigated, such as applications in ophthalmology, in bone repairing, in heart failure recovery, in post-stroke recovery, in tissue engineering, and regenerative medicine (TERM). Nevertheless, the most promising and developed applications of optogenetics are related to dynamic signal coding in cell physiology and neurological diseases. In this review, we will describe the state of the art and future insights on the impact of optogenetics on regenerative medicine.
Automatic Reproduction of Natural Head Position Using a Portable 3D Scanner Based on Immediate Calibration
Authors: Choi Min-Hyuk , Lee Sang-Jeong , Yang Hoon Joo , Huh Kyung-Hoe , Lee Sam-Sun , Heo Min-Suk , Choi Soon-Chul , Hwang Soon Jung , Yi Won-Jin
Published: December 2019

This paper developed a new method to easily record and automatically reproduce the 3D natural head position (NHP) of patients using a portable 3D scanner based on immediate calibration. We first optically scanned the patient’s face using a portable 3D scanner, and the scanned model was easily aligned with the global horizon based on an immediate calibration procedure using a developed calibration plate. The 3D patient NHP Computed Tomography(CT) model was reproduced automatically by performing registration between the CT model and the optically scanned model in the NHP using a modified coherent point drift (CPD) algorithm. In a phantom experiment, we evaluated the developed method’s accuracy using the error between the true and the calculated orientations in roll, pitch, and yaw directions. The mean difference was −0.05 ± 0.13°, 0.08 ± 0.22°, and −0.05 ± 0.18° in the roll, pitch, and yaw directions, respectively. The measured roll, pitch, and yaw directions were not significantly different from the true directions (p > 0.05). The calibration procedure for aligning the scanner coordinate system was easy enough for an inexperienced user to operate, and the 3D NHP CT model could be reproduced automatically. The developed method could be used for diagnosing and treating orthognathic patients with facial asymmetry accurately and conveniently in dental clinics.
Cell Membrane-Interrupting Antimicrobial Peptides from Isatis indigotica Fortune Isolated by a Bacillus subtilis Expression System
Authors: Wu Jia , Abbas Hafiz Muhammad Khalid , Li Jiale , Yuan Yuan , Liu Yunjun , Wang Guoying , Dong Wubei
Published: December 2019

The situation of drug resistance has become more complicated due to the scarcity of plant resistance genes, and overcoming this challenge is imperative. Isatis indigotica has been used for the treatment of wounds, viral infections, and inflammation for centuries. Antimicrobial peptides (AMPs) are found in all classes of life ranging from prokaryotes to eukaryotes. To identify AMPs, I. indigotica was explored using a novel, sensitive, and high-throughput Bacillus subtilis screening system. We found that IiR515 and IiR915 exhibited significant antimicrobial activities against a variety of bacterial (Xanthomonas oryzae, Ralstonia solanacearum, Clavibacter michiganensis, and C. fangii) and fungal (Phytophthora capsici and Botrytis cinerea) pathogens. Scanning electron microscope and cytometric analysis revealed the possible mechanism of these peptides, which was to target and disrupt the bacterial cell membrane. This model was also supported by membrane fluidity and electrical potential analyses. Hemolytic activity assays revealed that these peptides may act as a potential source for clinical medicine development. In conclusion, the plant-derived novel AMPs IiR515 and IiR915 are effective biocontrol agents and can be used as raw materials in the drug discovery field.
Salmonella Breaks Tumor Immune Tolerance by Downregulating Tumor Programmed Death-Ligand 1 Expression
Authors: Chen Man-Chin , Pangilinan Christian Ronquillo , Lee Che-Hsin
Published: December 2019

Immunotherapy is becoming a popular treatment modality in combat against cancer, one of the world’s leading health problems. While tumor cells influence host immunity via expressing immune inhibitory signaling proteins, some bacteria possess immunomodulatory activities that counter the symptoms of tumors. The accumulation of Salmonella in tumor sites influences tumor protein expression, resulting in T cell infiltration. However, the molecular mechanism by which Salmonella activates T cells remains elusive. Many tumors have been reported to have high expressions of programmed death-ligand 1 (PD-L1), which is an important immune checkpoint molecule involved in tumor immune escape. In this study, Salmonella reduced the expression of PD-L1 in tumor cells. The expression levels of phospho-protein kinase B (P-AKT), phospho-mammalian targets of rapamycin (P-mTOR), and the phospho-p70 ribosomal s6 kinase (P-p70s6K) pathway were revealed to be involved in the Salmonella-mediated downregulation of PD-L1. In a tumor-T cell coculture system, Salmonella increased T cell number and reduced T cell apoptosis. Systemic administration of Salmonella reduced the expressions of PD-L-1 in tumor-bearing mice. In addition, tumor growth was significantly inhibited along with an enhanced T cell infiltration following Salmonella treatment. These findings suggest that Salmonella acts upon the immune checkpoint, primarily PD-L1, to incapacitate protumor effects and thereby inhibit tumor growth.
Fenton and Photo-Fenton Nanocatalysts Revisited from the Perspective of Life Cycle Assessment
Authors: Feijoo Sara , González-Rodríguez Jorge , Fernández Lucía , Vázquez-Vázquez Carlos , Feijoo Gumersindo , Moreira María Teresa
Published: December 2019

This study provides an overview of the environmental impacts associated with the production of different magnetic nanoparticles (NPs) based on magnetite (Fe3O4), with a potential use as heterogeneous Fenton or photo-Fenton catalysts in wastewater treatment applications. The tendency of Fe3O4 NPs to form aggregates in water makes necessary their decoration with stabilizing agents, in order to increase their catalytic activity. Different stabilizing agents were considered in this study: poly(acrylic acid) (PAA), polyethylenimine (PEI) and silica (SiO2), as well as the immobilization of the magnetite-based catalysts in a mesoporous silica matrix, SBA-15. In the case of photo-Fenton catalysts, combinations of magnetite NPs with semiconductors were evaluated, so that magnetic recovery of the nanomaterials is possible, thus allowing a safe discharge free of NPs. The results of this study suggest that magnetic nanoparticles coated with PEI or PAA were the most suitable option for their applications in heterogeneous Fenton processes, while ZnO-Fe3O4 NPs provided an interesting approach in photo-Fenton. This work showed the importance of identifying the relevance of nanoparticle production strategy in the environmental impacts associated with their use.
TRPC Channels in Proteinuric Kidney Diseases
Authors: Hall Gentzon , Wang Liming , Spurney Robert F.
Published: December 2019

Over a decade ago, mutations in the gene encoding TRPC6 (transient receptor potential cation channel, subfamily C, member 6) were linked to development of familial forms of nephrosis. Since this discovery, TRPC6 has been implicated in the pathophysiology of non-genetic forms of kidney disease including focal segmental glomerulosclerosis (FSGS), diabetic nephropathy, immune-mediated kidney diseases, and renal fibrosis. On the basis of these findings, TRPC6 has become an important target for the development of therapeutic agents to treat diverse kidney diseases. Although TRPC6 has been a major focus for drug discovery, more recent studies suggest that other TRPC family members play a role in the pathogenesis of glomerular disease processes and chronic kidney disease (CKD). This review highlights the data implicating TRPC6 and other TRPC family members in both genetic and non-genetic forms of kidney disease, focusing on TRPC3, TRPC5, and TRPC6 in a cell type (glomerular podocytes) that plays a key role in proteinuric kidney diseases.
Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer
Authors: Hasselluhn Marie C. , Klein Lukas , Patzak Melanie S. , Buchholz Sören M. , Ströbel Philipp , Ellenrieder Volker , Maisonneuve Patrick , Neesse Albrecht
Published: December 2019

The KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) mouse model is frequently employed for preclinical therapeutic testing, in particular in regard to antistromal therapies. Here, we investigate the prognostic implications of histopathological features that may guide preclinical trial design. Pancreatic tumor tissue from n = 46 KPC mice was quantitatively analyzed using immunohistochemistry and co-immunofluorescence for proliferation (Ki67), mitotic rate (phospho-Histone 3, PHH3), apoptosis (cleaved caspase-3, CC3), collagen content, secreted protein acidic and rich in cysteine (SPARC), hyaluronic acid (HA), and α-smooth muscle actin (α-SMA). Furthermore, mean vessel density (MVD), mean lumen area (MLA), grading, activated stroma index (ASI), and fibroblast-proliferation rate (α-SMA/Ki67) were assessed. Univariate analysis using the Kaplan–Meier estimator and Cox regression model for continuous variables did not show association between survival and any of the analyzed parameters. Spearman correlation demonstrated that desmoplasia was inversely correlated with differentiated tumor grade (ρ = −0.84). Ki67 and PHH3 synergized as proliferation markers (ρ = 0.54), while SPARC expression was positively correlated with HA content (ρ = 0.37). MVD and MLA were correlated with each other (ρ = 0.31), while MLA positively correlated with CC3 (ρ = 0.45). Additionally, increased MVD was correlated with increased fibroblast proliferation rate (α-SMA + Ki67; ρ = 0.36). Our pilot study provides evidence that individual histopathological parameters of the primary tumor of KPC mice are not associated with survival, and may hint at the importance of systemic tumor-related effects such as cachexia.
Inclusion Complexes of Naringenin in Dimethylated and Permethylated β-Cyclodextrins: Crystal Structures and Molecular Dynamics Studies
Authors: Papaioannou Andreas , Christoforides Elias , Bethanis Kostas
Published: December 2019

The crystal structures of the inclusion complexes of naringenin in dimethylated and permethylated β-cyclodextrin (DM-β-CD and TM-β-CD) were determined and extensively analyzed. Naringenin is found with its 4-hydroxyphenyl residue fully immersed in the DM-β-CD cavity and its chromone group protruding from the narrow rim of the open-cone shaped host. The naringenin/DM-β-CD complex units are packed in a ‘herring bone’ fashion. In the case of naringenin/TM-β-CD, the complex units are arranged in a cage-type mode, the guest naringenin is partially encapsulated in the cavity of the closed-cone shaped host, with its chromone group laying equatorially and its 4-hydroxyphenyl protruding extensively from the wide rim of the host. Furthermore, the crystallographically-determined coordinates of both complexes were employed for Molecular Dynaimics simulations in explicit water solvent and in the absence of crystal contacts. The trajectories showed that naringenin rapidly penetrates the open narrow rim of DM-β-CD but not the closed narrow rim of TM-β-CD. Thus, in the latter case, the chromone group of naringenin is accommodated shallowly in the wide rim of the host, tethered via hydrogen bonds to the secondary methoxy groups of the host. Finally, a significantly higher binding affinity for naringenin in DM-β-CD than TM-β-CD was estimated by Molecular Mechanics/Generalized Born Surface Area calculations.
Many-Body Dynamics and Decoherence of the XXZ Central Spin Model in External Magnetic Field
Authors: Zhou Xu , Wan Qing-Kun , Wang Xiao-Hui
Published: December 2019

The many-body dynamics of an electron spin−1/2 qubit coupled to a bath of nuclear spins by hyperfine interactions, as described by the central spin model in two kinds of external field, are studied in this paper. In a completely polarized bath, we use the state recurrence method to obtain the exact solution of the X X Z central spin model in a constant magnetic field and numerically analyze the influence of the disorder strength of the magnetic field on fidelity and entanglement entropy. For a constant magnetic field, the fidelity presents non-attenuating oscillations. The anisotropic parameter λ and the magnetic field strength B significantly affect the dynamic behaviour of the central spin. Unlike the periodic oscillation in the constant magnetic field, the decoherence dynamics of the central spin act like a damping oscillation in a disordered field, where the central spin undergoes a relaxation process and eventually reaches a stable state. The relaxation time of this process is affected by the disorder strength and the anisotropic parameter, where a larger anisotropic parameter or disorder strength can speed up the relaxation process. Compared with the constant magnetic field, the disordered field can regulate the decoherence over a large range, independent of the anisotropic parameter.
Low Cycle Fatigue Life Prediction Using Unified Mechanics Theory in Ti-6Al-4V Alloys
Authors: Bin Jamal M Noushad , Kumar Aman , Lakshmana Rao Chebolu , Basaran Cemal
Published: December 2019

Fatigue in any material is a result of continuous irreversible degradation process. Traditionally, fatigue life is predicted by extrapolating experimentally curve fitted empirical models. In the current study, unified mechanics theory is used to predict life of Ti-6Al-4V under monotonic tensile, compressive and cyclic load conditions. The unified mechanics theory is used to derive a constitutive model for fatigue life prediction using a three-dimensional computational model. The proposed analytical and computational models have been used to predict the low cycle fatigue life of Ti-6Al-4V alloys. It is shown that the unified mechanics theory can be used to predict fatigue life of Ti-6Al-4V alloys by using simple predictive models that are based on fundamental equation of the material, which is based on thermodynamics associated with degradation of materials.
Asymmetric Contrarians in Opinion Dynamics
Authors: Galam Serge , Cheon Taksu
Published: December 2019

Asymmetry in contrarian behavior is investigated within the Galam model of opinion dynamics using update groups of size 3 with two competing opinions A and B. Denoting x and y the respective proportions of A and B contrarians, four schemes of implementations are studied. The first scheme activates contrarians after each series of updates with probabilities x and y for agents holding respectively opinion A and B. Second scheme activates contrarians within the update groups only against global majority with probability x when A is the majority and y when B is the majority. The third scheme considers in-group contrarians acting prior to the local majority update against both local majority and minority opinions. The last scheme activates in-group contrarians prior to the local majority update but only against the local majority. The main result is the loss of the fifty–fifty attractor produced by symmetric contrarians. Producing a bit less contrarians on its own side than the other side becomes the key to win a public debate, which in turn can guarantee an election victory. The associated phase diagram of opinion dynamics is found to exhibit a rich variety of counterintuitive results.
Learning the Macroscopic Flow Model of Short Fiber Suspensions from Fine-Scale Simulated Data
Authors: Yun Minyoung , Argerich Martin Clara , Giormini Pierre , Chinesta Francisco , Advani Suresh
Published: December 2019

Fiber–fiber interaction plays an important role in the evolution of fiber orientation in semi-concentrated suspensions. Flow induced orientation in short-fiber reinforced composites determines the anisotropic properties of manufactured parts and consequently their performances. In the case of dilute suspensions, the orientation evolution can be accurately described by using the Jeffery model; however, as soon as the fiber concentration increases, fiber–fiber interactions cannot be ignored anymore and the final orientation state strongly depends on the modeling of those interactions. First modeling frameworks described these interactions from a diffusion mechanism; however, it was necessary to consider richer descriptions (anisotropic diffusion, etc.) to address experimental observations. Even if different proposals were considered, none of them seem general and accurate enough. In this paper we do not address a new proposal of a fiber interaction model, but a data-driven methodology able to enrich existing models from data, that in our case comes from a direct numerical simulation of well resolved microscopic physics.
Assessment of Early Stopping through Statistical Health Prognostic Models for Empirical RUL Estimation in Wind Turbine Main Bearing Failure Monitoring
Authors: Herp Jürgen , Pedersen Niels L. , Nadimi Esmaeil S.
Published: December 2019

Details about a fault’s progression, including the remaining-useful-lifetime (RUL), are key features in monitoring, industrial operation and maintenance (O&M) planning. In order to avoid increases in O&M costs through subjective human involvement and over-conservative control strategies, this work presents models to estimate the RUL for wind turbine main bearing failures. The prediction of the RUL is estimated from a likelihood function based on concepts from prognostics and health management, and survival analysis. The RUL is estimated by training the model on run-to-failure wind turbines, extracting a parametrization of a probability density function. In order to ensure analytical moments, a Weibull distribution is assumed. Alongside the RUL model, the fault’s progression is abstracted as discrete states following the bearing stages from damage detection, through overtemperature warnings, to over overtemperature alarms and failure, and are integrated in a separate assessment model. Assuming a naïve O&M plan (wind turbines are run as close to failure as possible without regards for infrastructure or supply chain constrains), 67 non run-to-failure wind turbines are assessed with respect to their early stopping, revealing the potential RUL lost. These are turbines that have been stopped by the operator prior to their failure. On average it was found that wind turbines are stopped 13 days prior to their failure, accumulating 786 days of potentially lost operations across the 67 wind turbines.
Flexibility from Electric Boiler and Thermal Storage for Multi Energy System Interaction
Authors: Sinha Rakesh , Bak-Jensen Birgitte , Radhakrishna Pillai Jayakrishnan , Zareipour Hamidreza
Published: December 2019

Active use of heat accumulators in the thermal system has the potential for achieving flexibility in district heating with the power to heat (P2H) units, such as electric boilers (EB) and heat pumps. Thermal storage tanks can decouple demand and generation, enhancing accommodation of sustainable energy sources such as solar and wind. The overview of flexibility, using EB and storage, supported by investigating the nature of thermal demand in a Danish residential area, is presented in this paper. Based on the analysis, curve-fitting tools, such as neural net and similar day method, are trained to estimate the residential thermal demand. Utilizing the estimated demand and hourly market spot price of electricity, the operation of the EB is scheduled for storing and fulfilling demand and minimizing energy cost simultaneously. This demonstrates flexibility and controlling the EB integrated into a multi-energy system framework. Results show that the curve fitting tool is effectively suitable to acknowledge thermal demands of residential area based on the environmental factor as well as user behaviour. The thermal storage has the capability of operating as a flexible load to support P2H system as well as minimize the effect of estimation error in fulfilling actual thermal demand simultaneously.
Analysis of Photovoltaic String Failure and Health Monitoring with Module Fault Identification
Authors: Rivai Ahmad , Abd Rahim Nasrudin , Mohamad Elias Mohamad Fathi , Jamaludin Jafferi
Published: December 2019

In this paper, photovoltaic (PV) string failure analysis and health monitoring of PV modules based on a low-cost self-powered wireless sensor network (WSN) are presented. Simple and effective fault detection and diagnosis method based on the real-time operating voltage of PV modules is proposed. The proposed method is verified using the developed health monitoring system which is installed in a grid-connected PV system. Each of the PV modules is monitored via WSN to detect any individual faulty module. The analysis of PV string failure includes several electrical fault scenarios and their impact on the PV string characteristics. The results show that a degraded or faulty module exhibits low operating voltage as compared to the normal module. The developed health monitoring system also includes a graphical user interface (GUI) program which graphically displays the real-time operating voltage of each module with colors and thus helping users to identify the faulty modules easily. The faulty modules identification approach is further validated using the PV module electroluminescence (EL) imaging system.
Characteristics Analysis and Measurement of Inverter-Fed Induction Motors for Stator and Rotor Fault Detection
Authors: Tang Jing , Yang Yongheng , Chen Jie , Qiu Ruichang , Liu Zhigang
Published: December 2019

Inverter-fed induction motors (IMs) contain a serious of current harmonics, which become severer under stator and rotor faults. The resultant fault components in the currents affect the monitoring of the motor status. With this background, the fault components in the electromagnetic torque under stator faults considering harmonics are derived in this paper, and the fault components in current harmonics under rotor faults are analyzed. More importantly, the monitoring based on the fault characteristics (both in the torque and current) is proposed to provide reliable stator and rotor fault diagnosis. Specifically, the fault components induced by stator faults in the electromagnetic torque are discussed in this paper, and then, fault components are characterized in the torque spectrum to identify stator faults. To achieve so, a full-order flux observer is adopted to calculate the torque. On the other hand, under rotor faults, the sidebands caused by time and space harmonics in the current are analyzed and exploited to recognize rotor faults, being the motor current signature analysis (MCSA). Experimental tests are performed on an inverter-fed 2.2 kW/380 V/50 Hz IM, which verifies the analysis and the effectiveness of the proposed fault diagnosis methods of inverter-fed IMs.
Thermal Analysis of Power Semiconductor Device in Steady-State Conditions
Authors: Plesca Adrian
Published: December 2019

Electronic devices can be damaged in an undesirable manner if the junction temperature achieves high values in order to cause thermal runaway and melting. This paper describes the mathematical model to calculate the power losses in power semiconductor devices used in bidirectional rectifier which supplies a resistive-inductive load. The obtained thermal model can be used to analyse the thermal behaviour of power semiconductors in steady-state conditions, at different values of the firing angle, direct current, air speed in the case of forced cooling, and different types of load. Also, the junction and case temperature of a power thyristor have been computed. In order to validate the proposed mathematical model, some experimental tests have been performed. The theoretical values are in good concordance with the experimental data and simulated results.
Numerical and Experimental Study on the Heat Dissipation Performance of a Novel System
Authors: Yu Cairui , Shen Dongmei , Jiang Qingyang , He Wei , Yu Hancheng , Hu Zhongting , Chen Hongbing , Yu Pengkun , Zhang Sheng
Published: December 2019

In order to better release the heat generated by the electronic components, a novel heat dissipation system is proposed, which combines a microchannel heat pipe (MHP) with a high thermal conductivity and a radiative plate with a high emissivity at nighttime. First, a simple testing rig was made with an MHP and a radiative plate, where the radiative plate was made of acrylic resin, a curing agent, thinner, and aluminum plate, and had strong radiative cooling at nighttime. Second, the mathematical model was initially established and verified using experiments, where it was shown that the agreement between numerical and experimental data was well within experimental uncertainties. Comprehensive simulation investigations were conducted by varying wind speed, relative humidity, the cloudiness coefficient, dimension of the radiative plate, and tilted angle. The results show that: (1) the emissivity of the radiative plate was about 0.311 in the daytime and about 0.908 in the nighttime; (2) the influence of wind speed on reducing the component surface temperature was greater than the cloudiness coefficient and relative humidity; (3) the width of the radiative plate had a greater effect on heat dissipation than on its length, and the maximum size of radiative plate was recommended to be 400 mm × 400–500 mm (length × width), which was equipped with a single MHP (width: 60 mm). Additionally, the tilted angle of the radiative plate should be kept within 30° of the horizontal level. In conclusion, the novel heat dissipation system had a superior application value for providing assisted electronic component cooling in the nighttime.
Energy-Efficient Downlink for Non-Orthogonal Multiple Access with SWIPT under Constrained Throughput
Authors: Andrawes Admoon , Nordin Rosdiadee , Abdullah Nor Fadzilah
Published: December 2019

Non-Orthogonal Multiple Access (NOMA) has been proposed recently as an emerging radio access technology for the Fifth Generation (5G) to achieve high spectral efficiency (SE). In addition, simultaneous wireless information and power transfer (SWIPT) has been receiving exceptional attention because of its role in increasing energy efficiency (EE). In this paper, the performance of the downlink SWIPT-NOMA system has been evaluated. In this paper, signal to interference and noise ratio (SINR) is derived for near and far users with outage probability for each user, where the near user acts as an energy harvesting (EH) node. The Genetic algorithm (GA) is used as an optimization technique for the power splitting ratio and power allocation coefficients to maximize the EE under eligible SE. The outage probability for the near and far user is taken into consideration for the optimization process. In this work, the results from the SE–EE metric show that the maximum EE reached 0.325 Mbits/J at SE of 9 bits/sec/Hz.
Modelling of Passive Heat Removal Systems: A Review with Reference to the Framatome BWR Reactor KERENA: Part II
Authors: Manthey René , Viereckl Frances , Moonesi Shabestary Amirhosein , Zhang Yu , Ding Wei , Lucas Dirk , Schuster Christoph , Leyer Stephan , Hurtado Antonio , Hampel Uwe
Published: December 2019

Passive safety systems are an important feature of currently designed and constructed nuclear power plants. They operate independent of external power supply and manual interventions and are solely driven by thermal gradients and gravitational force. This brings up new needs for performance and reliably assessment. This paper provides a review on fundamental approaches to model and analyze the performance of passive heat removal systems exemplified for the passive heat removal chain of the KERENA boiling water reactor concept developed by Framatome. We discuss modeling concepts for one-dimensional system codes such as ATHLET, RELAP and TRACE and furthermore for computational fluid dynamics codes. Part I dealt with numerical and experimental methods for modeling of condensation inside the emergency condenser and on the containment cooling condenser. This second part deals with boiling and two-phase flow instabilities.
Transactive Energy to Thwart Load Altering Attacks on Power Distribution Systems
Authors: Yankson Samuel , Ghamkhari Mahdi
Published: December 2019

The automatic generation control mechanism in power generators comes into operation whenever an over-supply or under-supply of energy occurs in the power grid. It has been shown that the automatic generation control mechanism is highly vulnerable to load altering attacks. In this type of attack, the power consumption of multiple electric loads in power distribution systems is remotely altered by cyber attackers in such a way that the automatic generation control mechanism is disrupted and is hindered from performing its pivotal role. The existing literature on load altering attacks has studied implementation, detection, and location identification of these attacks. However, no prior work has ever studied design of an attack-thwarting system that can counter load altering attacks, once they are detected in the power grid. This paper addresses the above shortcoming by proposing an attack-thwarting system for countering load altering attacks. The proposed system is based on provoking real-time adjustment in power consumption of the flexible loads in response to the frequency disturbances caused by the load altering attacks. To make the adjustments in-proportion to the frequency disturbances, the proposed attack-thwarting system uses a transactive energy framework to establish a coordination between the flexible loads and the power grid operator.
Assessing Mechanical and Rheological Properties of Potato Puree: Effect of Different Ingredient Combinations and Cooking Methods on the Feasibility of 3D Printing
Authors: Dankar Iman , Haddarah Amira , Sepulcre Francesc , Pujolà Montserrat
Published: December 2019

The effects of agar, alginate, butter, olive oil, and carrots on the mechanical and rheological properties of potato puree prepared by two different cooking methods (microwave heating (MP) and boiling (BP)) were investigated and interpreted in terms of starch microstructural changes. Microscopic observations revealed more aggregated and densely concentrated starch granules in MP samples. This consequently led to a significant increase (p < 0.05) in mechanical and rheological properties up to five times more than BP samples. All samples exhibited shear thinning non-Newtonian behavior. Butter proved its ability to maintain stiff network formation with starch molecules forming lipid-starch complexes characterized by high retention properties and increased stability due to high thixotropic and yield stress values. The pseudo-plasticity combined with high self-supporting ability (high yield stress and mechanical values) comprised by MP samples allows them to better behave during advanced technological processes such as extrusion 3D food printing.
The Epigenetics Dilemma
Authors: Grunau Christoph , Le Luyer Jérémy , Laporte Martin , Joly Dominique
Published: December 2019

This special issue of Genes demonstrates clearly that research in epigenetics has proceeded at a very rapid pace in the last decade [...]