bluuebunny/crossref_metadata_2025 huggingface dataset:
Data-Driven Modeling of Human Development Index in Eastern Indonesia's Region Using Gaussian Techniques Empowered by Machine Learning
Authors: Ganiswari Syuhra Putri , Azies Harun Al , Nugraha Adhitya , Luthfiarta Ardytha , Firmansyah Gustian Angga
Published: December 2023

The Human Development Index (HDI) is a statistical measure used to measure and evaluate the progress and quality of human life in a country. For the Government of Indonesia, HDI is important because it is used to create or develop effective policies and programs. In addition, HDI is also used as one of the allocators in determining the General Allocation Fund. The 2022 HDI data released by BPS shows that there has been an increase in the HDI in each district/city over the last 12 years, including in the regions of Eastern Indonesia. High and low HDI values are influenced by several factors, and there are indications that there is spatial diversity where surrounding areas tend to have HDI levels that are not far from the area. The Geographically Weighted Regression method is used in this study because it takes into account spatial aspects. However, the GWR model must be built repeatedly if there is regional expansion. Therefore, a GWR model that applies machine learning methods is needed where the model is built and tested using different datasets, namely training data and test data, so that the model can predict new data better. The results obtained are that the GWR model with test data has a better R-Square value when compared to the GWR model previously trained using training data, which is 0.9946702, based on the linear regression model shows the results that the most influential factor on HDI in Eastern Indonesia is expected years of schooling (X2).
Analysis of Errors Identified during Regulatory Review of Risk Management Plans Submitted as Part of Registration Dossiers
Authors: Lovkova A. O. , Gyulakhmedova S. M. , Druzhinina A. A. , Nekipelova A. A.
Published: December 2023

Scientific relevance. On 6 December 2022, an updated version of the Rules for Good Pharmacovigilance Practice of the Eurasian Economic Union (EAEU GVP) came into force. The greatest changes were made to the requirements for pharmacovigilance documents, particularly the risk management plan (RMP). In practice, the changed EAEU GVP has resulted in multiple errors, creating the need to thoroughly analyse their structure and causes and to develop recommendations for their prevention.

Aim. This study aimed to identify, analyse, and collate inconsistencies between the information submitted by marketing authorisation holders in their RPMs and the updated EAEU GVP requirements.

Materials and methods. The Scientific Centre for Expert Evaluation of Medicinal Products analysed 50 RMPs received after 6 December 2022 as part of registration dossiers aimed to support marketing authorisation applications and/or align the registration dossiers with the EAEU requirements.

Results. The errors made by applicants when preparing RMPs were categorised according to their influence on the interpretation of a medicinal product’s safety profile. The errors leading to incorrect safety profile interpretations were considered type 1 errors (63% of the cases). The errors affecting the perception of the RMP but not the interpretation of the safety profile (e.g., grammatical errors, notes and comments by applicants, incorrect translation of terms) were deemed type 2 errors (37% of the cases). The majority of EAEU GVP noncompliance cases were detected in Part II of the RMP, the section providing the most information on the safety profile of a medicinal product.

Conclusions. There are several ways to improve the quality of RMP preparation. The information included in the RMP should be compared with the information provided in the registration dossier. The RMP should be incorporated into the integrated pharmaceutical quality system according to the requirements of good practices.

A responsible employee of the marketing authorisation holder’s quality assurance system should control the final RMP version. Employees of pharmacovigilance departments should receive regular training.
On recovering the shape of a quantum tree from the spectrum of the Dirichlet boundary problem
Authors: Boyko O. , Martynyuk O. , Pivovarchik V.
Published: December 2023

Spectral problems are considered generated by the Sturm-Liouville equation on equilateral trees with the Dirichlet boundary conditions at the pendant vertices and continuity and Kirchhoff's conditions at the interior vertices. It is proved that there are no co-spectral (i.e., having the same spectrum of such problem) among equilateral trees of $\leq 8$ vertices. All co-spectral trees of $9$ vertices are presented.
Developing a Research–Practice Partnership With Policy Intermediaries: An Examination of Collaboration With State Education Agency Leaders
Authors: Weddle Hayley
Published: December 2023

A growing body of scholarship foregrounds research–practice partnerships (RPPs) as venues for advancing equity in education. However, few studies focus on partnerships with state education agency leaders, despite their influential roles connecting policy and practice. This article explores state leaders’ experiences collaborating in an early-phase, national RPP focused on advancing multilingual learner equity. Findings shed light on how joint work was facilitated through the development of evidence-based resources addressing current problems of practice. Findings also demonstrate the importance of attending to leaders’ dual responsibilities across state and local levels, informing future efforts to foster partnerships with state leaders. Future research is needed to examine the sustainability of state-level RPPs, as well as the experiences of researchers engaging in such partnerships.
Typification of names published by P. S. Pallas in Astragalus and Phaca, now in genus Oxytropis sect. Orobia (Fabaceae)
Authors: Sytin A. K. , Byalt V. V. , Sokolova I. V.
Published: December 2023

The original material used by P. S. Pallas in his descriptions of 7 species in the genus Astragalus L. and 1 species in Phaca L., all now classified within the genus Oxytropis DC. section Orobia Bunge, is analysed and discussed. The lectotypes of Astragalus altaicus Pall. (Oxytropisaltaica (Pall.) Pers.), A. argentatus Pall. (O. argentata (Pall.) Pers.), A. candicans Pall. (O. candicans (Pall.) DC.), A. grandiflorus Pall. (O. grandiflora (Pall.) DC.), A. songaricus Pall. (O. songarica (Pall.) DC.), A. spicatus Pall. (O. spicata (Pall.) O. Fedtsch. et B. Fedtsch.), Phaca sylvatica Pall. (O. sylvatica (Pall.) Willd.), and the epitype of Astragalus spicatus (O. spicata) are designated.
On the Monetary Dialogue between the European Central Bank and the European Parliament: From monetary monologue to dialogue—and beyond?
Authors: Diessner Sebastian
Published: December 2023

This essay traces the evolution of the communication between the European Central Bank (ECB) and the European Parliament (EP) over the past 25 years of Monetary Dialogues between the two supranational institutions. The essay begins with a reflection on the political problem of central bank communication. It then sketches out three distinct phases of ECB-EP relations over time. The main contention is that ECB communication with the EP has started, and should continue, to move from a one-way street to a multi-way street, in the interest of further improving the democratic credentials of EMU.
KESENJANGAN PERAN: IBU RUMAH TANGGA SEBAGAI PENCARI NAFKAH UTAMA DALAM KONTEKS NILAI DAN NORMA
Authors: Rahman Agnia Alviaturr
Published: December 2023

In the contemporary era, traditional family roles are undergoing significant transformations amid changes in social, economic, and cultural dynamics. This research, titled "Role Discrepancy: Homemakers as Primary Breadwinners in the Context of Values and Norms," delves deeper into this phenomenon. The understanding of the homemaker's role as the primary breadwinner continues to evolve, challenging established family norms and values. This study aims to identify the factors driving this change and analyze its impact on family interactions and cohesion. The history of family dynamics has always been closely linked to societal values and norms. However, with rapid changes in aspects of life such as economic shifts and the evolution of gender roles, family values and norms are also undergoing transformations. The first part of this research delves into the question of whether there is an identified shift in the values and social norms surrounding the role of homemakers as primary breadwinners. The decision of a homemaker to take on the role of the primary breadwinner brings complex implications for family dynamics. The second segment of this research analyzes the impact of this decision on day-to-day interactions within the family, the redistribution of responsibilities, and the formation of the family unit as a whole. Focusing on these changes, this research attempts to deepen our understanding of the intricate dynamics of relationships within the family. Furthermore, role shifts within the family can create disparities and conflicts. The final segment of this research highlights potential conflicts or tensions within the family that may arise in connection with the economic role of the homemaker. By detecting and analyzing these potential sources of conflict, this research provides in-depth insights into the dynamics of relationships and the challenges faced by families experiencing shifts in roles within the modern family structure. Through this approach, the research aims to provide a more holistic understanding of the homemaker's role as the primary breadwinner and how shifts in values and norms can shape family dynamics amid ongoing societal changes.
Classical Sorting Algorithms as a Model of Morphogenesis: self-sorting arrays reveal unexpected competencies in a minimal model of basal intelligence
Authors: Zhang Taining , Goldstein Adam , Levin Michael
Published: December 2023

The Diverse Intelligence research seeks to understand commonalities in behavioral competencies across a wide range of implementations. Especially interesting are simple systems that provide unexpected examples of memory, decision-making, or problem-solving in substrates that at first glance do not appear to be complex enough to implement such capabilities. We seek to develop tools to determine minimal requirements for such capabilities, and to learn to recognize and predict basal forms of intelligence in unconventional substrates. Here, we apply novel analyses to the behavior of classical sorting algorithms - short pieces of code studied for many decades. To study these sorting algorithms as a model of biological morphogenesis and its competencies, we break two formerly-ubiquitous assumptions: top-down control (instead, each element within an array of numbers can exert minimal agency and implement sorting policies from the bottom up), and fully reliable hardware (instead, allowing elements to be “damaged” and fail to execute the algorithm). We quantitatively characterize sorting activity as traversal of a problem space, showing that arrays of autonomous elements sort themselves more reliably and robustly than traditional implementations in the presence of errors. Moreover, we find the ability to temporarily reduce progress in order to navigate around a defect, and unexpected clustering behavior among elements in chimeric arrays consisting of two different algorithms. The discovery of emergent problem-solving capacities in simple, familiar algorithms contributes a new perspective showing how basal forms of intelligence can emerge in simple systems without being explicitly encoded in their underlying mechanics.
The seven deadly sins of set theory
Authors: Mueckenheim Wolfgang
Published: December 2023

Seven internal contradictions of set theory are discussed.
Mekanisme Pasar Tradisional Mimbaan di Situbondo: Analisis Perspektif Islam Teori Ibn Taimiyah
Authors: Sheila Avi Dinda Putri
Published: December 2023

Market mechanism is a process of price formation based on the forces of demand and supply. The traditional market of Mimbaan, Situbondo City, price formation is currently not only influenced by changes in demand and supply, but there are other factors that influence it. However, Ibn Taymiyyah said that price fixing occurs because of the balance of demand and supply. Sellers and buyers are the main actors of the mechanism problems that occur in the market and the main one is price fixing. This observation uses a qualitative method, and obtains data by collecting data by conducting interviews. As for analyzing the data, the author uses the descriptive analysis method. In the observation, there was a discrepancy between the traditional market mechanism of Mimbaan, Situbondo City and the market mechanism of Ibn Taymiyyah's thought. However, there are also some things that are in accordance with Ibn Taymiyyah's opinion on pricing. If the market mechanism of Ibn Taymiyyah's thought is applied to the traditional market of Mimbaan, it is possible to ensure the balance of the market price of an item and prevent the occurrence of imperfect market mechanisms.
Fixed point properties of numbered families
Authors: Faizrahmanov Marat
Published: December 2023

In this paper, we prove a joint generalization of Arslanov’s completenesscriterion and Visser’s ADN theorem for precomplete numberings. Then we considerthe properties of completeness and precompleteness of numberings in the context ofthe positivity property. We show that the completions of positive numberings are nottheir minimal covers and that the Turing completeness of any set A is equivalent to theexistence of a positive precomplete A-computable numbering of any infinite family withpositive A-computable numbering.
The Politics of Monetary Union and the Democratic Legitimacy of the ECB as a Strategic Actor
Authors: Diessner Sebastian
Published: December 2023

Any take on the politics of monetary policy starts from the recognition that a de facto separation of central banking from democratic processes is impossible to achieve fully in a democratic society, even if it is mandated de iure in the form of central bank independence. This implies that monetary authorities, like the European Central Bank (ECB), can and should be evaluated not only in terms of how well they perform according to their own mandates, but also in terms of wider normative criteria of democratic legitimation. This chapter thus submits that to make sense of the politics of Europe’s monetary union we need to focus on the multi-dimensional issue of the legitimacy of the ECB.
Conflict regulation in flavour perception
Authors: Drew Alice Albertini , Zampini Massimiliano , Soto-Faraco Salvador
Published: December 2023

For many, flavour is the quintessential multisensory experience. The perception of flavour arises from the concurrent processing of inputs across a wide variety of sensory modalities, including but not limited to taste, smell, sound, several somatosensory channels as well as a range of other cues that help generate expectations about the flavour object (visual cues, smell through the nose, contextual cues, etc). For these bundles of inputs to be experienced as a unitary flavour percept, and to lead to a positive hedonic response, a certain degree of agreement between them is necessary. Remarkably, despite the mounting amounts of empirical evidence currently available, a framework to understand the processes triggered by sensory (in)congruence in flavour perception is lacking. Here, we consider the psychophysical, cognitive, and neural mechanisms related to flavour congruency within the framework of conflict monitoring. More specifically, we argue that brain mechanisms monitoring for, signalling, and eventually orchestrating the resolution of sensory discrepancies are decisive for the emergence of a unified subjective flavour percept, and its associated hedonic appraisal. This framework could help to elucidate certain well documented facets of the experience of flavour such as attentional processes, hedonic responses and perhaps even expectancy effects as well as suggest new avenues for future research.
Herausforderungen und Potenziale der NRO-Schulzusammenarbeit für Globales Lernen an Schulen.Empirische Befunde einer Studie zu NRO-Mitarbeitenden
Authors: Eich Lena
Published: December 2023

Die Zusammenarbeit von entwicklungspolitischen Nichtregierungsorganisationen (NRO) und Schulen ist im Kontext Globalen Lernens bereits seit vielen Jahren etabliert. Zum Handeln der NRO-Mitarbeitenden an Schulen liegen jedoch kaum Studien vor. In diesem Artikel werden Ergebnisse einer qualitativen Studie zu handlungsleitenden Orientierungen von NRO-Mitarbeitenden vorgestellt. Datengrundlage bilden die 16 narrativen Interviews mit NRO-Mitarbeitenden, die mithilfe der dokumentarischen Methode rekonstruktiv ausgewertet wurden. Die drei generierten Typen von Handlungsorientierungen werden im Hinblick auf Herausforderungen und Potenziale der Zusammenarbeit für Globales Lernen an Schulen kritisch beleuchtet.
PEMBERDAYAAN MASYARAKAT PADA UMKM KAMPUNG KUE
Authors: Rahmawati Dewi , Nawangsari Ertien Rining
Published: December 2023

Salah satu sektor perdagangan besar dan eceran yang terkenal di Surabaya adalah berbagai jenis Usaha Mikro Kecil Menengah (UMKM). Kampung Kue merupakan salah satu kelompok UMKM di Surabaya dengan produk olahan kue tradisional yang didominasi oleh ibu-ibu pekerja rumahan. Dengan total lebih dari 70 pelaku usaha menunjukkan bahwa UMKM di Kampung Kue memiliki kualitas dan keunggulan dibanding kampung-kampung lainnya. Namun para pengrajin kue masih menghadapi berbagai permasalahan seperti kurangnya kepemilikan NIB, sertifikasi halal yang belum menyeluruh, dan sedikitnya pelaku usaha yang menjual produknya di E-Peken. Dengan permasalahan tersebut, peneliti tertarik meneliti pemberdayaan yang dilakukan Pemerintah Surabaya pada UMKM Kampung Kue. Tujuan utama penelitian ini untuk mengetahui, mendeskripsikan, dan menganalisis tentang pemberdayaan masyarakat pada UMKM Kampung Kue di Rungkut Lor Gang II Kecamatan Rungkut Kota Surabaya. Jenis Penelitian yang digunakan adalah deskriptif kualitatif. Pada penelitian ini menggunakan teknik pengumpulan data dengan observasi dan wawancara kepada informan yaitu pemerintah daerah, pendiri sekaligus ketua paguyuban UMKM Kampung Kue dan para UMKM Kampung Kue. Selanjutnya, model analisis data dalam penelitian ini menggunakan analisis data interaktif terdiri atas pengumpulan data, penyajian data, kondensasi data dan penarikan kesimpulan. Teori yang digunakan adalah Pemberdayaan Masyarakat menurut Mardikanto (2014) dalam (Maryani, 2020) yang terdapat 6 (enam) indikator perbaikan. Hasil penelitian menunjukkan 4 (empat) indikator perbaikan yang telah dilakukan optimal. Tetapi, 2 (dua) indikator perbaikan belum dilakukan optimal dalam pemberdayaan UMKM Kampung Kue di Rungkut Lor Gang II Kecamatan Rungkut Kota Surabaya.
If I Met a Jew – What Would I talk to Him/Her About? The Possibilities of Creative Writing and Post Shoah Literature in the Czech Language
Authors: Hrdinová Eva Maria , Dömischová Ivona
Published: December 2023

В статье рассматривается возможность использования практики писательского мастерства для преподавания иностранным студентам темы Холокоста в литературе. Анализируются такие конкретные авторы, как Эгон Хостовский, Иржи Вайль и Йозеф Шкворецкий. Также обсуждаются конкретные практики творческого писательского мастерства, проявляющиеся в индивидуальных работах студентов.
ДОСЛІДЖЕННЯ ОПЕРАЦІЇ ВИЗНАЧЕННЯ НАЛЕЖНОСТІ ЧИСЛА ДО ДАНОЇ ПОЛОВИНИ ІНТЕРВАЛУ ЧИСЕЛ В СИСТЕМІ ЗАЛИШКОВИХ КЛАСІВ З УСІМА ПАРНИМИ МОДУЛЯМИ
Authors: Ю.Д. Поліський
Published: December 2023

У роботі досліджено систему залишкових класів з усіма парними модулями щодо визначення належності числа до верхньої або нижньої половини інтервалу чисел.
ЛІНІЙНІ ОПЕРАТОРИ В ЗАДАЧАХ ПОШУКУ ЕКСТРЕМУМУ ДЛЯ ШВИДКО ОСЦИЛЮЮЧИХ ФУНКЦІЙ ТА ЗАДАЧАХ СКЛАДАННЯ РОЗКЛАДУ ПРЕДСТАВЛЕНИМИ ДИСКРЕТНИМИ ФУНКЦІЯМИ
Authors: С.М. Бажан , Л.О. Олійник
Published: December 2023

У роботі представлено математичну модель операторної модифікації генетичного алгоритму для дослідження процесів, що моделюються швидко осцилюючими та дискретними функціями. Досліджувалося застосування лінійних операторів в теорії еволюційних алгоритмів, зокрема генетичного алгоритму з практичним застосуванням до задач оптимізації. Запропонований підхід застосовувався до задачі пошуку глобального екстремуму функції однієї змінної та до задачі складання розв’язку закладу освіти. Розроблено алгоритм пошуку мінімального значення із застосуванням лінійних операторів, що належать до класу стохастичних операторів. Проведено дослідження працездатності та ефективності алгоритму на відомих тестових функціях, таких як Растригіна, Швефеля, Лангермана, Михайловича, Хін-Ши Янга. В роботі наведено результати порівняння запропонованої операторної модифікації генетичного алгоритму з класичним генетичним алгоритмом для трьох тестових функцій. А також запропоновано на базі застосування спеціальних лінійних операторів метод пошуку придатного до практичного використання розкладу занять. Представлено опис операторів, схематичне відображення їх застосування, та безпосередньо приклад застосування до матриці розкладу деякої академічної групи.
КОМП’ЮТЕРНЕ МОДЕЛЮВАННЯ ЗГИНУ МЕТАЛЕВИХ БАЛОК РІЗНИХ ПРОФІЛІВ
Authors: О.М. Клєцков , В.М. Сахно
Published: December 2023

Металеві балки є одними з найпоширеніших структурних елементів в будівництві та інженерних конструкціях. Вони використовуються для підтримки та розподілу навантаження, що дозволяє створювати стійкі та ефективні споруди. Одним із ключових аспектів проектування металевих балок є їх згин.

Дослідження згину металевих балок різних профілів мають велике значення для інженерів та дизайнерів, оскільки вони допомагають зрозуміти поведінку матеріалів і визначити оптимальні розміри та форму конструкцій. Проведення таких досліджень включає в себе використання аналітичних методів, експериментальних досліджень та чисельних моделей.

Одним з результатів дослідження згину металевих балок є встановлення залежності між профілем балки, її розмірами, матеріалом та здатністю переносити навантаження. Ці дані можуть бути використані для розробки нормативних документів та стандартів, які регулюють проектування сталевих конструкцій. Застосування відповідних профілів для балок є ключовим аспектом в проектуванні. Вибір оптимального профілю залежить від багатьох факторів, таких як очікуване навантаження, довжина балки, припустимі деформації та вартість матеріалу. Дослідження дозволяють визначити профіль, який найкраще задовольняє усі ці вимоги.

Проведений порівняльний аналіз між аналітичним методом та комп’ютерним моделюванням показав, що найбільш близьке співпадіння до теоретичного значення спостерігається при моделюванні в Abaqus, тоді як в Ansys спостерігається значне зростання похибки з ускладненням виду профілю. Значне зростання похибки зумовлене в першу чергу недостатньою кількістю елементів сітки на яку ділить програма балку, згідно методу скінченних елементів. Тож для випралення значного відхилення від теоретичного значення при моделюванні в Ansys потрібно згущювати сітку. Однією з задач дослідження було проведення моделювання згину в різних програмах при рівних умовах, тобто однаковій кількості елементів сітки, а при таких умовах Abaqus має перевагу перед Ansys.
МАТЕМАТИЧНЕ ТА КОМП'ЮТЕРНЕ МОДЕЛЮВАННЯ ТЕПЛОМАСОПЕРЕНОСНИХ ПРОЦЕСІВ ПРИ ЗАПОВНЕННІ ВИЛИВНИЦІ РОЗПЛАВОМ СТАЛІ
Authors: Т.Ж. Надригайло , Є.В. Жорнік
Published: December 2023

У даній роботі досліджується процес заповнення ливарної форми розплавленою сталлю зверху, представлена математична модель досліджуваного процесу та розроблено її програмну реалізацію. Проведено чисельні дослідження для задачі заповнення виливниці розплавом сталі зверху з урахуванням газозахоплення, виконано перевірку моделі на адекватність та проаналізовано поведінку газорідинного середовища, що формується у виливниці під час її заповнення розплавом, з урахуванням впливу газозахоплення.
МОДЕЛЮВАННЯ РОЗПОДІЛУ РОБОЧОГО НАВАНТАЖЕННЯ КОЛІНЧАТОГО ВАЛА ТА ТЕХНОЛОГІЇ ЗМІЦНЕННЯ ПОВЕРХОНЬ ТЕРТЯ
Authors: О.Г. Чернета , Б.П. Середа , В.І. Кубіч
Published: December 2023

Довговічність і надійність роботи автомобілів, деталей і механізмів залежать від багатьох факторів і основним з них є якість кожної окремої деталі. Як визначалося у багатьох інформаційних джерелах, показники якості мають багатовекторний, комплексний склад — від матеріалу, хімічного складу, мікро і макроструктури, технологій, режимів обробки, стану поверхневого шару і т.п. до фізико механічних властивостей. В сучасному виробництві деталей машинобудівного комплексу необхідно враховувати не уклінне зростання навантажень (швидкість, температура, агресивне середовище) на механізми і деталі, що складають цільний продукт машинобудівного призначення.

В останні часи набули поширене використання диференційовані або комбіновані обробки поверхневого шару деталей, що сприяють виникненню градієнтів структурно — фазового стану, а відповідно і нерівномірної структури матеріалу. При необхідності суттєвого зміцнення поверхневого шару і твердості матеріалу необхідно попередньо проводити обробку для отримання відповідних структур (мартенситу, карбідів, нітридів, боридів та т.ін.), що забезпечує задані властивості.

Для оцінки стану поверхневого шару деталей із сталі 45 необхідно урахувати наступні фактори: геометричні параметри розмірів, шорсткість поверхні деталі, мікроструктуру і твердість зношених поверхневих шарів.
A Script Analysis of Successful Police Interventions Involving Individuals in Crisis
Authors: Blais Etienne , Leclerc Benoit
Published: December 2023

This study uses script analysis in criminology to identify steps and actions performed by police officers during their encounters with individuals in crisis to obtain their cooperation peacefully. Data were collected from 130 police reports. Descriptive and logistic regression analyses were respectively used to identify the main steps of police interventions and to estimate the effect of police actions on reactions from the person in crisis. A six-step script was identified: (1) receiving the emergency call; (2) arriving at the scene; (3) assessing the situation; (4) engaging with the person in crisis; (5) managing the situation; and (6) completing the intervention. During their interventions, officers use several techniques to obtain the cooperation of the person in crisis or de-escalate the crisis. Results indicate that support techniques (e.g., involving the person in finding a solution) lead to cooperation and permit effective de-escalation of the crisis. Conversely, individuals in crisis were less likely to cooperate or calm down when the police used nonphysical (e.g., using threats, disapproving of the person’s behavior) or physical control techniques (e.g., using constraint or intermediate weapons). Measures likely to improve police interventions with individuals in crisis are discussed, using the script analysis as a framework.
Myeloperoxidase/paraoxonase ratio as a prognostic marker for post-COVID syndrome in patients undergoing hemodialysis: A cross-sectional cohort study
Authors: Korol L. , Stepanova N. , Popova O. , Malashevska N. , Vasylchenko V. , Ostapenko T. , Rysyev A. , Kolesnyk M.
Published: December 2023

The present study aimed to assess the impact of post-COVID syndrome on the oxidative status and activity of paraoxonase 1 (PON-1), myeloperoxidase (MPO), and leukocyte elastase in the blood of patients undergoing hemodialysis (HD).

Methods. In this cross-sectional cohort study, 290 patients undergoing HD were included. The oxidative status was assessed based on the levels of blood malondialdehyde (MDA), ceruloplasmin, thiol compounds (SH-groups), and the serum activities of myeloperoxidase (MPO), paraoxonase-1 (PON-1), and elastase were determined.

Results. It was found that HD patients exhibited an elevation in oxidative processes, characterized by increased blood concentrations of MDA, MPO, elastase activity, and a decrease in the levels of SH-groups and arylesterase activity of PON-1. Patients with post-COVID syndrome showed further increases in MPO activity and a decrease in arylesterase activity of PON-1. Additionally, a statistically significant elevation in the MPO/PON-1 ratio was observed in HD patients with post-COVID syndrome compared to the control group and patients examined before the onset of the pandemic (p < 0.0001). The MPO/PON-1 ratio exhibited a direct correlation with serum MDA levels (p < 0.0001) and inversely correlated with the concentration of ceruloplasmin (p = 0.0008). The MPO/PON-1 value surpassing 9.06 units was identified as a predictive marker for PCS, demonstrating a specificity of 68.4% and a sensitivity of 88.5%.

Conclusions. Our study highlights a significant impact of post-COVID syndrome on oxidative processes in HD patients, as evidenced by elevated MDA levels and MPO activity, along with reduced levels of antioxidants and arylesterase activity of PON-1. The MPO/PON-1 ratio emerges as a promising predictive marker for post-COVID syndrome, underlining its potential clinical relevance in identifying at-risk patients.
Prescribing patterns of new oral anticoagulants in patients with atrial fibrillation and chronic kidney disease: A narrative review
Authors: Chernatska O.
Published: December 2023

This study aimed to investigate the prescribing patterns of new oral anticoagulants in atrial fibrillation patients based on creatinine clearance. A thorough analysis of articles published between 2017 and 2021 in databases such as PubMed, Scopus, and Google Scholar was conducted.

The review revealed distinctive features in the use of new oral anticoagulants concerning glomerular filtration rate. Apixaban was identified as a judicious choice for individuals with kidney disorders, with approximately 25% of its dose excreted in urine. American guidelines specifically recommend apixaban for those with a creatinine clearance of less than 15 mL/min, while European recommendations contraindicate all new oral anticoagulants for such rates.

In instances where the glomerular filtration rate ranges from 15 to 29 mL/min, apixaban or edoxaban may be preferred due to the substantial renal elimination of edoxaban. Reduced dose regimens of rivaroxaban, edoxaban, and apixaban are advised for individuals with chronic kidney disease and a creatinine clearance between 15 and 30 mL/min.

Dabigatran, characterized by an 80% renal elimination rate, is recommended for individuals with a creatinine clearance exceeding 30 ml/min according to European guidelines and those with a clearance of at least 15 ml/min according to American guidelines.
Специфика продвижения личного дизайнерского бренда в социальных медиаресурсах: монография, [электронное издание сетевого распространения] / Д.Э. Янукян, М.Б. Янукян. – М.: «КДУ»; «Добросвет», 2023. – 162 с.
Authors: Янукян Д.Э. , Янукян М.Б.
Published: December 2023

В монографии изучены и описаны сетевые медиаресурсы, используемые для создания и продвижения модных брендов в социальных сетях, что особенно востребовано в условиях динамично развивающегося интернет-пространства. На основе системного анализа использования инструментов PR для продвижения бренда в сфере индустрии моды определен набор PR-инструментов для формирования и развития брендов в социальных сетях, выделены как универсальные PR инструменты, которые в равной степени используются и массовыми, и дизайнерскими брендами, так и специфические для каждого из них. Собраны и систематизированы сведения о PR-инструментах в аспекте их возможностей и преимуществ для продвижения модных брендов, обозначены особенности использования PR-инструментов для продвижения массовых марок и успешных брендов, привлечения определенных социальных сетей в зависимости от их целевой аудитории.
ALTERNATIVE CERTIFICATION FOR SPECIAL EDUCATION TEACHERS IN KENTUCKY
Authors: Shumaieva Svitlana
Published: December 2023

The article is devoted to the issue of training special education teachers in Kentucky in a non-traditional way, with the help of alternative programs. The author provides a general description of such programs: analyzes their content, considers the forms and methods of training “alternative” teachers of special education. It was determined that the primary goal of creating alternative teacher certification programs was to fill the overall teacher shortage. However, in the process of implementation, the programs varied and were refined, which ultimately led to a change in their functionality. Alternative training programs began to be created as early as the 1980s and provided for the stimulation of an increase in the total number of teachers. It was found that each state has its own principles regarding alternative teacher certification. Most states have established unique alternative teaching certification programs. Many states have more than one program, allowing candidates to choose an option. It was found that in 2017‒2018 only 13.7% of all public school students in the United States were eligible for IDEA programm. Therefore, the Kentucky Department of Education (KDE) has made a significant effort to increase the number of qualified special education teachers in the state by developing eight alternative teacher certification pathways for those interested in entering the teaching profession. The majority of educational institution administrations have a positive attitude towards alternative programs. That’s why was made a conclusion regarding the importance of this type of pedagogical training to ensure the necessary number of pedagogical workers and maintain high standards of education in the USA.

Keywords: alternative programs; alternative teacher certification; special teacher training programs; professional development; special education; teaching profession; pedagogical training; non-traditional training programs.
THE RELATIONSHIP OF BUS VENTILATION WITH ITS FRONTAL RESISTANCE COEFFICIENT
Authors: Dovbush O. , Voznyak O. , Savchenko O. , Spodyniuk N.
Published: December 2023

The article presents the results of a study of the influence of natural and mechanical ventilation of the cabin and the driver's cabin on the air flow of the bus. Experimental studies were carried out in wind tunnels. Based on the measurements, the distribution of air velocities in the boundary layer was determined. In addition, the influence of natural ventilation of the interior space on the thickness of the air boundary layer was analyzed. The results are presented by means of a distribution diagram and analytical dependences. The purpose of this study is to determine both the thickness of the boundary layer when air passes through the car model and the drag coefficient. Experimental studies of the flow of a bus model in a wind tunnel have been carried out. It is determined that when the speed of air supply is increased, the ventilation supply devices should be placed in the rear part of the bus, and the exhaust devices should be placed in the front part of the bus. This measure improves body flow while the bus is moving. As a result, the coefficient of frontal resistance decreases and its economic indicator of fuel consumption improve.
Cross-cultural competence as a component of integration into the european scientific and educational space
Authors: Suprun Daria , Suprun Mykola
Published: December 2023

The educational environment of higher education institutions acquires universally inclusive characteristics, which allows it to reflect and respond to the needs and demands of all participants in society without exception. In this aspect we have to research cross-cultural competence as a component of integration into the european scientific and educational space. For achievement the aim with tasks, the set of complementary methods was applied: theoretical methods: (analysis, synthesis, comparison, generalization) were used to find out the state of the problem; empirical (direct and indirect observation, standardized questionnaire survey, semi-standardized individual interviews), psychodiagnostic methods and research techniques; statistical analysis. Thus, according to research it is obvious that modern social, political, and economic realities, transformational processes in the state education system, also significantly change established views regarding the professional level and personal qualities of specialists. There is no doubt that thier level of preparation must meet international standards that formulate the requirements of competitiveness not only in the labor market of Ukraine, but also in other foreign countries. Modern university graduates have to demonstrate not only the variability of knowledge, show interpersonal empathy and tolerance for any diversity, but also have developed prognostic and reflective skills, possess cross- and multicultural competences, demonstrate professional mobility.
Content and structural aspects of communicative competence as a component of the professional qualities of future psychologists
Authors: Shevtsova Olena , Prokhorenko Ya.
Published: December 2023

The article analyzes scientific sources on the problem of the peculiarities of the formation of communicative competence in future psychologists. Communication competence is a necessary element for the successful practice of psychology, as it determines the psychologist's ability to interact with clients, effectively communicate information and establish deep understanding. The article analyzes various aspects of the formation of communicative competence in future psychologists. First of all, the theoretical foundations of the components of communicative competence are considered, including cognitive, communicative-speech, social-perceptive and interactive. The content aspects of communicative competence are considered: mastery of language skills, understanding of non-verbal signals and the ability to show empathy. The role of active listening, adequate use of language and flexibility in communication with different categories of people is investigated. The author also provides recommendations on the development of structural components of communicative competence in future psychologists.
Historical and cultural analysis of ideas on the formation of aesthetic culture of the individual
Authors: Shmarko Nataliia , Hrechanyk Nataliia
Published: December 2023

The article highlights some issues related to the formation of aesthetic culture of the individual through the historical and cultural prism. The analysis of philosophical ideas on the category of culture and aesthetics of the individual from the ancient era to the present is chronologically presented, which led to the derivation of basic research positions. The definition of the concept of aesthetic culture of the individual is presented, which is an instrument of holistic and conscious perception of beauty in art and reality, the ability to creative self-expression inherent in man. Attention is focused on the exclusivity of this property of personality as a natural and culturally appropriate human need, but which requires conscious, purposeful and systematic formation with prospective development. The author emphasizes that the primary goal in the formation of aesthetic culture is to rely on the identification of artistic and aesthetic characteristics of the individual with their prospective development to the level of aesthetically appropriate human ability to master the surrounding reality. It is assumed that such a level is manifested both in the integrated development of all segments of the aesthetic consciousness of the individual and in the development of skills and abilities of active transformative activity in art, work, life, and socio-cultural processes. It is substantiated that the main task of forming aesthetic culture is not only to expand the range of artistic perception, the number of books read, musical pieces heard, etc. but also to consciously generate feelings, spiritual growth of the individual, regulation and correction of behavior. In this context, the tasks of aesthetic education are specified, which are the development of sensory (sensual culture), the education of aesthetic tastes and value judgments, and the development of artistic creativity.
Analysis of the awareness of personal responsibility for interpersonal and social conflicts (based on the application of the author's psychological exercises)
Authors: Osadchenko Inna
Published: December 2023

The article, based on the analysis of scientific sources and empirical material, characterizes the method of analyzing the awareness of personal responsibility for the course of interpersonal and social conflicts, composed of three author's exercises: "Communication Style Circles"; "Vibrations: "I am in conflict", "Vibrations: "I and the World (society/other people)". Methodological approaches to the development of each psychological exercise are substantiated. It was concluded that nowadays we are used to consider social conflict as a "separate", independent "mechanism", forgetting that each person is a component of the system, and a set of negative psycho-emotional states, intrapersonal and interpersonal conflicts give rise to social conflict, from the point of view of the systemic approach. At the same time, an individual's understanding of this aspect is not yet an awareness and an unequivocal change in worldview and personal conflict behavior, because everyone continues to "expect" that: a) The world "must change first in a conflict"; b) the social conflict must be changed by "someone" (the government, a specific president, the military, etc.); c) a person, i.e. a personal conflict psycho-emotional state (intrapersonal conflict), cannot in any way influence social conflict, etc. It was concluded that people are used to perceiving the "threat" of conflict from the outside - from the World - and do not think at all about the impact of intrapersonal conflict on the World. The concept of "mirror reflection of personal conflict behavior" is introduced. The reasons for personal conflict behavior are defined as: a) selfishness of each person; b) reluctance to work on oneself, primarily on the correction of negative psycho-emotional states (elimination of intrapersonal conflict); c) the formation of the habit of such social behavior and the constant creation of interpersonal conflicts; c) indifference and irresponsibility as typical moral qualities of a modern person, etc. The development of a separate socio-educational technology is required for the formation of noospheric, in-depth anti-conflict thinking, awareness of personal responsibility for the course of the conflict.
Exploring the nature of consciousness: Michael Grazino's attention scheme theory and Bernard Baars' global workspace theory
Authors: Derid Kostyantyn , Dodonova Vera
Published: December 2023

The article examines the modern discourse on the problem of consciousness in the context of theories about the biological and physical basis of consciousness. In order to consider problematic issues of consciousness, two theoretical approaches to consciousness are analyzed: Michael Graziano's attention schema theory and Bernard Baars' global workspace theory. By describing the key characteristics of each approach, it is determined what aspects of consciousness they propose to explain, what their neurobiological commitments are, and what empirical evidence is cited to support them. Researching the theories of Michael Graziano and Bernard Baars helps in understanding how the brain creates conscious experience, which is key to progress in the field of cognitive science and neuroscience. Understanding the nature of consciousness is important for philosophical and ethical discussions related to questions of responsibility, self-awareness, and other aspects of social existence. The research also promotes interaction between different fields of science, such as neurobiology, psychology, philosophy and computer science, which creates an integrated approach to the study of consciousness. When writing this article, the following methods were used: discourse analysis, in order to obtain substantiated information about the theories of consciousness of Michael Graziano and Bernard Baars, about various aspects of theories of consciousness, their main principles and interaction with other theories. Comparativist approach: a comparative analysis of the theories of Michael Graziano and Bernard Baars was carried out, highlighting their common and distinctive features. Comprehensive approach: a wide range of knowledge and information was used to write the article in order to provide a complete and objective overview of theories of consciousness.
Exploring the formation of individual educational paths for bachelor's and master's students at NULES of Ukraine
Authors: Klikh Larysa , Zazymko Oksana , Rudyk Yaroslav
Published: December 2023

The article investigates the role of selective educational components in constructing personalized educational trajectories for bachelor's and master's degree recipients. It delves into the legislative framework that upholds the right of higher education seekers to shape their individual educational paths. The NULES of Ukraine's experience is detailed, emphasizing the allocation of selective educational components into blocks of free choice aligned with the educational program and tailored to the preferences of the recipients of educational services. The article also sheds light on overarching trends in credit distribution within undergraduate and graduate educational programs. It provides a rationale for the annual update procedure of the list of disciplines in the block of free choice, considering student preferences and presenting options for combining optional disciplines.
The concept of interactive learning technologies
Authors: Prytyka О. І.
Published: December 2023

The article analyzes the essence and main aspects of the use of interactive technologies in the learning process. The concept of interactive technologies is defined as means aimed at active interaction of students with educational material. The article highlights the key benefits of using interactive technologies, such as increasing the interest and motivation of students, creating a favorable environment for individualized learning and developing critical thinking. Possible challenges and limitations associated with the introduction of interactive technologies into the educational process are also discussed. Interactive technologies make it possible to create a more dynamic and memorization-promoting learning environment. They help students to remember more and better understand the educational material thanks to visualization, animation and interactive tasks. With the help of interactive technologies, the educational material can be adapted to the specific needs and level of knowledge of each student. This allows each student to learn at their own pace and focus on their own needs. Multimedia tools and interactive applications help to visualize abstract or complex material, which facilitates understanding and memorization. Interactive learning technologies are an approach to education that actively uses various technologies to engage students in the learning process. These technologies are aimed at creating interaction between students, teachers and educational material. The main principles of interactive learning technologies include active participation of students, individualization of learning and the use of different learning formats.