bluuebunny/crossref_metadata_2025 huggingface dataset:
BOUNDED TOEPLITZ AND HANKEL PRODUCTS ON THE WEIGHTED BERGMAN SPACES OF THE UNIT BALL
Authors: MICHALSKA MAŁGORZATA , SOBOLEWSKI PAWEŁ
Published: July 2015

Let $A_{{\it\alpha}}^{p}$ be the weighted Bergman space of the unit ball in ${\mathcal{C}}^{n}$, $n\geq 2$. Recently, Miao studied products of two Toeplitz operators defined on $A_{{\it\alpha}}^{p}$. He proved a necessary condition and a sufficient condition for boundedness of such products in terms of the Berezin transform. We modify the Berezin transform and improve his sufficient condition for products of Toeplitz operators. We also investigate products of two Hankel operators defined on $A_{{\it\alpha}}^{p}$, and products of the Hankel operator and the Toeplitz operator. In particular, in both cases, we prove sufficient conditions for boundedness of the products.
THE PRO-p-IWAHORI HECKE ALGEBRA OF A REDUCTIVEp-ADIC GROUP III (SPHERICAL HECKE ALGEBRAS AND SUPERSINGULAR MODULES)
Authors: Vigneras Marie-France
Published: July 2015

Let$R$be a large field of characteristic$p$. We classify the supersingular simple modules of the pro-$p$-Iwahori Hecke$R$-algebra${\mathcal{H}}$of a general reductive$p$-adic group$G$. We show that the functor of pro-$p$-Iwahori invariants behaves well when restricted to the representations compactly induced from an irreducible smooth$R$-representation$\unicode[STIX]{x1D70C}$of a special parahoric subgroup$K$of$G$. We give an almost-isomorphism between the center of${\mathcal{H}}$and the center of the spherical Hecke algebra${\mathcal{H}}(G,K,\unicode[STIX]{x1D70C})$, and a Satake-type isomorphism for${\mathcal{H}}(G,K,\unicode[STIX]{x1D70C})$. This generalizes results obtained by Ollivier for$G$split and$K$hyperspecial to$G$general and$K$special.
NON-UNITARISABLE REPRESENTATIONS AND MAXIMAL SYMMETRY
Authors: Ferenczi Valentin , Rosendal Christian
Published: July 2015

We investigate questions of maximal symmetry in Banach spaces and the structure of certain bounded non-unitarisable groups on Hilbert space. In particular, we provide structural information about bounded groups with an essentially unique invariant complemented subspace. This is subsequently combined with rigidity results for the unitary representation of $\text{Aut}(T)$ on $\ell _{2}(T)$, where $T$ is the countably infinite regular tree, to describe the possible bounded subgroups of $\text{GL}({\mathcal{H}})$ extending a well-known non-unitarisable representation of $\mathbb{F}_{\infty }$.

As a related result, we also show that a transitive norm on a separable Banach space must be strictly convex.
Deciphering population structure and diversity inLuffa cylindrica(L.) M. Roem. using morphological and sequence-related amplified polymorphism markers
Authors: Tyagi Ruchi , Sharma Vinay , Sureja Amish Kumar , Munshi Anilabh Das , Arya Lalit , Verma Manjusha
Published: July 2015

Luffa cylindrica(L.) M. Roem. is an underutilized vegetable and a potential biodiesel crop for future. Its fruits are edible and used as vegetable. To aid in the selection of lines for breeding, genetic variation and structure of ten populations ofL. cylindricawere determined with three morphological characters and 23 sequence-related amplified polymorphism (SRAP) markers. All the three morphological characters were found diverse among 45 accessions. The SRAP primers produced a total of 177 bands, out of which 129 were polymorphic. Informative markers assessed by different measures (polymorphism information content = 0.18, marker index = 1.26, resolving power = 2.87) will direct the selection of primers for cultivar identification inL. cylindrica. Low level of genetic differentiation among populations and higher level within populations (Gst= 0.4073,Nm= 0.7277,He= 0.124,I= 0.20) was detected that might be due to cross-pollinated nature ofL. cylindrica. The clustering pattern obtained through dendrogram and principal coordinate analysis was loosely concordant with the geographical distribution. The Bayesian structure analysis indicated an admixture type of population distribution. The results designate that SRAP and morphological markers are informative for characterization ofL. cylindricaand identification of distinctive cultivars.
Influence of different soil management practices on ground-flora vegetation in an almond orchard
Authors: Fracchiolla M. , Terzi M. , Frabboni L. , Caramia D. , Lasorella C. , De Giorgio D. , Montemurro P. , Cazzato E.
Published: July 2015

This paper reports a survey on the weed flora and seed bank in an almond orchard sited in Apulia region (Southern Italy), where the following soil management practices have been compared for over 30 yrs: no-tillage, keeping the soil totally weed-free throughout the year by using pre-emergence herbicides to prevent plant emergence or post-emergence herbicides in case of weeds already emerged; no-tillage, with post-emergence herbicides; no-tillage, with mowing of natural weed flora in spring; cover cropping, with faba bean sown in November and green manured in springtime; conventional soil tillage. The different management techniques influenced significantly the weed flora in experimental plots, both in terms of quantity and quality. The seed bank was clearly impoverished after the long-term applications of pre-emergence herbicides, both in terms of richness and of diversity. During the fall period, the plots of conventional tillage or pre-emergence herbicides had less natural ground-flora than the others. During springtime, prior to the sward control practices, the plots treated by foliar herbicides or mowing had the highest total weed cover. We conclude that post-emergence weed control by mowing or using chemical herbicides or the green manure of the cover crop may be proposed to reduce impact to the soil and to promote the growth of abundant and sufficiently diversified and balanced flora. If appropriately managed, this flora can provide potential ecological services, without competing with the orchard, as suggested by the literature. During the autumn, natural flora can uptake soil nitrogen thus preventing leaching in the rainy season. In springtime, after the sward has been destroyed, natural flora can supply a substantial amount of biomass to the soil. Indicator species analysis was also used to find the species characterizing each treatment and some of their combinations. Weeds belonging to thePoaceaebotanical family were significantly associated with post-emergence herbicides and mowing treatments. These species produce a substantial amount of biomass and have bunched roots; consequently, they supply beneficial effects by improving porosity and structure of the soil and reducing erosion hazard.
Confirmed record of the Ambon scorpionfish Pteroidichthys amboinensis (Teleostei: Scorpaenidae) from the Red Sea
Authors: Fricke Ronald , Golani Daniel , Appelbaum-Golani Brenda
Published: July 2015

The Red Sea record of the Ambon scorpionfishPteroidichthys amboinensisis confirmed based on two specimens collected at Eilat, Israel in 1966 and in 1997. The species is widespread but very rare, known from scattered localities in the Indo-West Pacific, otherwise occurring from India and Indonesia east to Marquesas Islands.
New Pluto Image Reveals Young Icy Plain
Authors: Wendel JoAnna
Published: July 2015

The mottled plain offers additional evidence that Pluto's surface is geologically young—and possibly still active.
Shifts in bacterial community composition associated with increased carbon cycling in a mosaic of phytoplankton blooms
Authors: Landa Marine , Blain Stéphane , Christaki Urania , Monchy Sébastien , Obernosterer Ingrid
Published: July 2015

Marine microbes have a pivotal role in the marine biogeochemical cycle of carbon, because they regulate the turnover of dissolved organic matter (DOM), one of the largest carbon reservoirs on Earth. Microbial communities and DOM are both highly diverse components of the ocean system, yet the role of microbial diversity for carbon processing remains thus far poorly understood. We report here results from an exploration of a mosaic of phytoplankton blooms induced by large-scale natural iron fertilization in the Southern Ocean. We show that in this unique ecosystem where concentrations of DOM are lowest in the global ocean, a patchwork of blooms is associated with diverse and distinct bacterial communities. By using on-board continuous cultures, we identify preferences in the degradation of DOM of different reactivity for taxa associated with contrasting blooms. We used the spatial and temporal variability provided by this natural laboratory to demonstrate that the magnitude of bacterial production is linked to the extent of compositional changes. Our results suggest that partitioning of the DOM resource could be a mechanism that structures bacterial communities with a positive feedback on carbon cycling. Our study, focused on bacterial carbon processing, highlights the potential role of diversity as a driving force for the cycling of biogeochemical elements.
Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation
Authors: Yoon Jeong-Hwan , Sudo Katsuko , Kuroda Masahiko , Kato Mitsuyasu , Lee In-Kyu , Han Jin Soo , Nakae Susumu , Imamura Takeshi , Kim Juryun , Ju Ji Hyeon , Kim Dae-Kee , Matsuzaki Koichi , Weinstein Michael , Matsumoto Isao , Sumida Takayuki , Mamura Mizuko
Published: July 2015

Transforming growth factor-β (TGF-β) and interleukin-6 (IL-6) are the pivotal cytokines to induce IL-17-producing CD4+ T helper cells (TH17); yet their signalling network remains largely unknown. Here we show that the highly homologous TGF-β receptor-regulated Smads (R-Smads): Smad2 and Smad3 oppositely modify STAT3-induced transcription of IL-17A and retinoic acid receptor-related orphan nuclear receptor, RORγt encoded by Rorc, by acting as a co-activator and co-repressor of STAT3, respectively. Smad2 linker phosphorylated by extracellular signal-regulated kinase (ERK) at the serine 255 residue interacts with STAT3 and p300 to transactivate, whereas carboxy-terminal unphosphorylated Smad3 interacts with STAT3 and protein inhibitor of activated STAT3 (PIAS3) to repress the Rorc and Il17a genes. Our work uncovers carboxy-terminal phosphorylation-independent noncanonical R-Smad–STAT3 signalling network in TH17 differentiation.
Drivers of the US CO2 emissions 1997–2013
Authors: Feng Kuishuang , Davis Steven J. , Sun Laixiang , Hubacek Klaus
Published: July 2015

Fossil fuel CO2 emissions in the United States decreased by ∼11% between 2007 and 2013, from 6,023 to 5,377 Mt. This decline has been widely attributed to a shift from the use of coal to natural gas in US electricity production. However, the factors driving the decline have not been quantitatively evaluated; the role of natural gas in the decline therefore remains speculative. Here we analyse the factors affecting US emissions from 1997 to 2013. Before 2007, rising emissions were primarily driven by economic growth. After 2007, decreasing emissions were largely a result of economic recession with changes in fuel mix (for example, substitution of natural gas for coal) playing a comparatively minor role. Energy–climate policies may, therefore, be necessary to lock-in the recent emissions reductions and drive further decarbonization of the energy system as the US economy recovers and grows.
Eliminating material constraints for nonlinearity with plasmonic metamaterials
Authors: Neira Andres D. , Olivier Nicolas , Nasir Mazhar E. , Dickson Wayne , Wurtz Gregory A. , Zayats Anatoly V.
Published: July 2015

Nonlinear optical materials comprise the foundation of modern photonics, offering functionalities ranging from ultrafast lasers to optical switching, harmonic and soliton generation. Optical nonlinearities are typically strong near the electronic resonances of a material and thus provide limited tuneability for practical use. Here we show that in plasmonic nanorod metamaterials, the Kerr-type nonlinearity is not limited by the nonlinear properties of the constituents. Compared with gold’s nonlinearity, the measured nonlinear absorption and refraction demonstrate more than two orders of magnitude enhancement over a broad spectral range that can be engineered via geometrical parameters. Depending on the metamaterial’s effective plasma frequency, either a focusing or defocusing nonlinearity is observed. The ability to obtain strong and fast optical nonlinearities in a given spectral range makes these metamaterials a flexible platform for the development of low-intensity nonlinear applications.
Preventing breast cancer now by acting on what we already know
Authors: Colditz Graham A , Bohlke Kari
Published: July 2015

The age-specific rate of breast cancer rises rapidly through premenopausal years and significantly more slowly after menopause. Reproductive factors affect cell proliferation and the accumulation of genetic changes. Lifetime risk of breast cancer is linearly related to the length of the interval from menarche to first birth. Lifestyle changes that accompany industrialization, together with shifting reproductive patterns, drive up incidence rates. Prevention must begin early in the life as almost one-quarter of cases are diagnosed before age 50 in high-income countries. This requires greater emphasis on prevention across the life course to address the global burden of breast cancer.
Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin
Authors: Chang Lan , Cui Wei , Yang Yong , Xu Shujun , Zhou Wenhua , Fu Hongjun , Hu Shengquan , Mak Shinghung , Hu Juwei , Wang Qin , Pui-Yan Ma Victor , Chung-lit Choi Tony , Dik-lung Ma Edmond , Tao Liang , Pang Yuanping , Rowan Michael J. , Anwyl Roger , Han Yifan , Wang Qinwen
Published: July 2015

β-amyloid (Aβ) oligomers have been closely implicated in the pathogenesis of Alzheimer’s disease (AD). We found, for the first time, that bis(heptyl)-cognitin, a novel dimeric acetylcholinesterase (AChE) inhibitor derived from tacrine, prevented Aβ oligomers-induced inhibition of long-term potentiation (LTP) at concentrations that did not interfere with normal LTP. Bis(heptyl)-cognitin also prevented Aβ oligomers-induced synaptotoxicity in primary hippocampal neurons. In contrast, tacrine and donepezil, typical AChE inhibitors, could not prevent synaptic impairments in these models, indicating that the modification of Aβ oligomers toxicity by bis(heptyl)-cognitin might be attributed to a mechanism other than AChE inhibition. Studies by using dot blotting, immunoblotting, circular dichroism spectroscopy and transmission electron microscopy have shown that bis(heptyl)-cognitin altered Aβ assembly via directly inhibiting Aβ oligomers formation and reducing the amount of preformed Aβ oligomers. Molecular docking analysis further suggested that bis(heptyl)-cognitin presumably interacted with the hydrophobic pockets of Aβ, which confers stabilizing powers and assembly alteration effects on Aβ. Most importantly, bis(heptyl)-cognitin significantly reduced cognitive impairments induced by intra-hippocampal infusion of Aβ oligomers in mice. These results clearly demonstrated how dimeric agents prevent Aβ oligomers-induced synaptic and memory impairments and offered a strong support for the beneficial therapeutic effects of bis(heptyl)-cognitin in the treatment of AD.
A microfluidic device to study neuronal and motor responses to acute chemical stimuli in zebrafish
Authors: Candelier Raphaël , Sriti Murmu Meena , Alejo Romano Sebastián , Jouary Adrien , Debrégeas Georges , Sumbre Germán
Published: July 2015

Zebrafish larva is a unique model for whole-brain functional imaging and to study sensory-motor integration in the vertebrate brain. To take full advantage of this system, one needs to design sensory environments that can mimic the complex spatiotemporal stimulus patterns experienced by the animal in natural conditions. We report on a novel open-ended microfluidic device that delivers pulses of chemical stimuli to agarose-restrained larvae with near-millisecond switching rate and unprecedented spatial and concentration accuracy and reproducibility. In combination with two-photon calcium imaging and recordings of tail movements, we found that stimuli of opposite hedonic values induced different circuit activity patterns. Moreover, by precisely controlling the duration of the stimulus (50–500 ms), we found that the probability of generating a gustatory-induced behavior is encoded by the number of neurons activated. This device may open new ways to dissect the neural-circuit principles underlying chemosensory perception.
An Efficient Genome-Wide Fusion Partner Screening System for Secretion of Recombinant Proteins in Yeast
Authors: Bae Jung-Hoon , Hyun Sung Bong , Kim Hyun-Jin , Park Soon-Ho , Lim Kwang-Mook , Kim Mi-Jin , Lee Cho-Ryong , Sohn Jung-Hoon
Published: July 2015

To produce rarely secreted recombinant proteins in the yeast Saccharomyces cerevisiae, we developed a novel genome-wide optimal translational fusion partner (TFP) screening system that involves recruitment of an optimal secretion signal and fusion partner. A TFP library was constructed from a genomic and truncated cDNA library by using the invertase-based signal sequence trap technique. The efficiency of the system was demonstrated using two rarely secreted proteins, human interleukin (hIL)-2 and hIL-32. Optimal TFPs for secretion of hIL-2 and hIL-32 were easily selected, yielding secretion of these proteins up to hundreds of mg/L. Moreover, numerous uncovered yeast secretion signals and fusion partners were identified, leading to efficient secretion of various recombinant proteins. Selected TFPs were found to be useful for the hypersecretion of other recombinant proteins at yields of up to several g/L. This screening technique could provide new methods for the production of various types of difficult-to-express proteins.
Identification of PblB mediating galactose-specific adhesion in a successful Streptococcus pneumoniae clone
Authors: Hsieh Yu-Chia , Lin Tzu-Lung , Lin Che-Ming , Wang Jin-Town
Published: July 2015

The pneumococcal genome is variable and there are minimal data on the influence of the accessory genome on phenotype. Pneumococcal serotype 14 sequence type (ST) 46 had been the most prevalent clone causing pneumonia in children in Taiwan. A microarray was constructed using the genomic DNA of a clinical strain (NTUH-P15) of serotype 14 ST46. Using DNA hybridization, genomic variations in NTUH-P15 were compared to those of 3 control strains. Microarray analysis identified 7 genomic regions that had significant increases in hybridization signals in the NTUH-P15 strain compared to control strains. One of these regions encoded PblB, a phage-encoded virulence factor implicated (in Streptococcus mitis) in infective endocarditis. The isogenic pblB mutant decreased adherence to A549 human lung epithelial cell compared to wild-type NTUH-P15 strain (P = 0.01). Complementation with pblB restored the adherence. PblB is predicted to contain a galactose-binding domain-like region. Preincubation of NTUH-P15 with D-galactose resulted in decreases of adherence to A549 cell in a dose-dependent manner. Challenge of mice with NTUH-P15, isogenic pblB mutant and pblB complementation strains determined that PblB was required for bacterial persistence in the nasopharynx and lung. PblB, as an adhesin mediating the galactose-specific adhesion activity of pneumococci, promote pneumococcal clonal success.
Dosimetric Comparison and Evaluation of Three Radiotherapy Techniques for Use after Modified Radical Mastectomy for Locally Advanced Left-sided Breast Cancer
Authors: Ma Changchun , Zhang Wuzhe , Lu Jiayang , Wu Lili , Wu Fangcai , Huang Baotian , Lin Yan , Li Dongsheng
Published: July 2015

This study aimed to compare the post-modified radical mastectomy radiotherapy (PMRMRT) for left-sided breast cancer utilizing 3-dimensional conformal radiotherapy with field-in-field technique (3DCRT-FinF), 5-field intensity-modulated radiation therapy (5F-IMRT) and 2- partial arc volumetric modulated arc therapy (2P-VMAT). We created the 3 different PMRMRT plans for each of the ten consecutive patients. We performed Kruskal-Wallis analysis of variance (ANOVA) followed by the Dunn’s-type multiple comparisons to establish a hierarchy in terms of plan quality and dosimetric benefits. P < 0.05 was considered statistically significant. Both 5F-IMRT and 2P-VMAT plans exhibited similar PTV coverage (V95%), hotspot areas (V110%) and conformity (all p > 0.05) and significantly higher PTV coverage compared with 3DCRT-FinF (both p < 0.001). In addition, 5F-IMRT plans provided significantly less heart and left lung radiation exposure than 2P-VMAT (all p < 0.05). The 3DCRT-FinF plans with accurately estimated CTV displacement exhibited enhanced target coverage but worse organs at risk (OARs) sparing compared with those plans with underestimated displacements. Our results indicate that 5F-IMRT has dosimetrical advantages compared with the other two techniques in PMRMRT for left-sided breast cancer given its optimal balance between PTV coverage and OAR sparing (especially heart sparing). Individually quantifying and minimizing CTV displacement can significantly improve dosage distribution.
Surmounting intrinsic quantum-measurement uncertainties in Gaussian-state tomography with quadrature squeezing
Authors: Řeháček Jaroslav , Teo Yong Siah , Hradil Zdeněk , Wallentowitz Sascha
Published: July 2015

We reveal that quadrature squeezing can result in significantly better quantum-estimation performance with quantum heterodyne detection (of H. P. Yuen and J. H. Shapiro) as compared to quantum homodyne detection for Gaussian states, which touches an important aspect in the foundational understanding of these two schemes. Taking single-mode Gaussian states as examples, we show analytically that the competition between the errors incurred during tomogram processing in homodyne detection and the Arthurs-Kelly uncertainties arising from simultaneous incompatible quadrature measurements in heterodyne detection can often lead to the latter giving more accurate estimates. This observation is also partly a manifestation of a fundamental relationship between the respective data uncertainties for the two schemes. In this sense, quadrature squeezing can be used to overcome intrinsic quantum-measurement uncertainties in heterodyne detection.
Nonfunctional ingestion of plant miRNAs in silkworm revealed by digital droplet PCR and transcriptome analysis
Authors: Jia Ling , Zhang Dayan , Xiang Zhonghuai , He Ningjia
Published: July 2015

Since a plant miRNA (miR168) cross-regulating a mammalian transcript was reported, miRNA-mediated cross-kingdom communication has become one of the most compelling but controversial topics. In the present study, we used silkworm and mulberry, which is a model for studies on the interactions between the insect and its host plant, to address whether miRNA-mediated cross-kingdom communication is a common phenomenon. The results of TA clone, Sanger sequencing and droplet digital PCR demonstrated that several mulberry-derived miRNAs could enter to silkworm hemolymph and multiple tested tissues. Synthetic miR166b was also detected in hemolymph and fat body. However, the ingestion of synthetic miR166b did not play roles in silkworm physiological progress, which was revealed by RNA-seq analyses, RT-PCR and phenotypic investigations. Mulberry miRNAs are convincingly transferred to the silkworm orally and no physiological process associated with the miRNAs was demonstrable. The results provided a new aspect of cross-kingdom miRNA transfer.
Circadian and ultradian rhythms of clock gene expression in the suprachiasmatic nucleus of freely moving mice
Authors: Ono Daisuke , Honma Ken-ichi , Honma Sato
Published: July 2015

In mammals, the temporal order of physiology and behavior is primarily regulated by the circadian pacemaker located in the hypothalamic suprachiasmatic nucleus (SCN). Rhythms are generated in cells by an auto-regulatory transcription/translation feedback loop, composed of several clock genes and their protein products. Taking advantage of bioluminescence reporters, we have succeeded in continuously monitoring the expression of clock gene reporters Per1-luc, PER2::LUC and Bmal1-ELuc in the SCN of freely moving mice for up to 3 weeks in constant darkness. Bioluminescence emitted from the SCN was collected with an implanted plastic optical fiber which was connected to a cooled photomultiplier tube. We found robust circadian rhythms in the clock gene expression, the phase-relation of which were the same as those observed ex vivo. The circadian rhythms were superimposed by episodic bursts which had ultradian periods of approximately 3.0 h. Episodic bursts often accompanied activity bouts, but stoichiometric as well as temporal analyses revealed no causality between them. Clock gene expression in the SCN in vivo is regulated by the circadian pacemaker and ultradian rhythms of unknown origin.
Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury
Authors: Lin Weiwei , Yuan Na , Wang Zhen , Cao Yan , Fang Yixuan , Li Xin , Xu Fei , Song Lin , Wang Jian , Zhang Han , Yan Lili , Xu Li , Zhang Xiaoying , Zhang Suping , Wang Jianrong
Published: July 2015

Autophagy is essentially a metabolic process, but its in vivo role in nuclear radioprotection remains unexplored. We observed that ex vivo autophagy activation reversed the proliferation inhibition, apoptosis and DNA damage in irradiated hematopoietic cells. In vivo autophagy activation improved bone marrow cellularity following nuclear radiation exposure. In contrast, defective autophagy in the hematopoietic conditional mouse model worsened the hematopoietic injury, reactive oxygen species (ROS) accumulation and DNA damage caused by nuclear radiation exposure. Strikingly, in vivo defective autophagy caused an absence or reduction in regulatory proteins critical to both homologous recombination (HR) and non-homologous end joining (NHEJ) DNA damage repair pathways, as well as a failure to induce these proteins in response to nuclear radiation. In contrast, in vivo autophagy activation increased most of these proteins in hematopoietic cells. DNA damage assays confirmed the role of in vivo autophagy in the resolution of double-stranded DNA breaks in total bone marrow cells as well as bone marrow stem and progenitor cells upon whole body irradiation. Hence, autophagy protects the hematopoietic system against nuclear radiation injury by conferring and intensifying the HR and NHEJ DNA damage repair pathways and by removing ROS and inhibiting apoptosis.
A new functional classification system (FGA/B) with prognostic value for glioma patients
Authors: Friedlein Katharina , Bozhkov Yavor , Hore Nirjhar , Merkel Andreas , Sommer Björn , Brandner Sebastian , Buchfelder Michael , Savaskan Nicolai E. , Eyüpoglu Ilker Y.
Published: July 2015

Despite advances in multimodal treatments, malignant gliomas remain characterized by a short survival time. Surgical treatment is accepted to be the first line of therapy, with recent studies revealing that maximal possible tumor reduction exerts significant impact on patient outcome. Consideration of tumor localization in relation to functionally eloquent brain areas has been gaining increasing importance. Despite existing assessment methods, the availability of a simple but reliable preoperative grading based on functional data would therefore prove to be indispensable for the prediction of postoperative outcome and hence for overall survival in glioma patients. We performed a clinical investigation comprising 322 patients with gliomas and developed a novel classification system of preoperative tumor status, which considers tumor operability based on two graduations (Friedlein Grading - FG): FGA with lesions at safe distance to eloquent regions which can be completely resected and FGB referring to tumors which can only be partially resected or biopsied. Investigation of outcome revealed that FGA were characterized by a significantly longer overall survival time compared to FGB. We offer the opportunity to classify brain tumors in a dependable and reproducible manner. The FGA/B grading method provides high prognostic value with respect to overall survival time in relation to the extent of location-dependent tumor resection.
The oxytocin system promotes resilience to the effects of neonatal isolation on adult social attachment in female prairie voles
Authors: Barrett C E , Arambula S E , Young L J
Published: July 2015

Genes and social experiences interact to create variation in social behavior and vulnerability to develop disorders of the social domain. Socially monogamous prairie voles display remarkable diversity in neuropeptide receptor systems and social behavior. Here, we examine the interaction of early-life adversity and brain oxytocin receptor (OTR) density on adult social attachment in female prairie voles. First, pups were isolated for 3 h per day, or unmanipulated, from postnatal day 1–14. Adult subjects were tested on the partner preference (PP) test to assess social attachment and OTR density in the brain was quantified. Neonatal social isolation impaired female PP formation, without affecting OTR density. Accumbal OTR density was, however, positively correlated with the percent of time spent huddling with the partner in neonatally isolated females. Females with high accumbal OTR binding were resilient to neonatal isolation. These results are consistent with the hypothesis that parental nurturing shapes neural systems underlying social relationships by enhancing striatal OTR signaling. Thus, we next determined whether early touch, mimicking parental licking and grooming, stimulates hypothalamic OT neuron activity. Tactile stimulation induced immediate-early gene activity in OT neurons in neonates. Finally, we investigated whether pharmacologically potentiating OT release using a melanocortin 3/4 agonist, melanotan-II (10 mg kg−1 subcutaneously), would mitigate the social isolation-induced impairments in attachment behavior. Neonatal melanotan-II administration buffered against the effects of early isolation on partner preference formation. Thus, variation in accumbal OTR density and early OT release induced by parental nurturing may moderate susceptibility to early adverse experiences, including neglect.
Multi-walled carbon nanotubes: innovative sorbents for pre-concentration of polychlorinated biphenyls in aqueous environments
Authors: Ndunda Elizabeth N. , Mizaikoff Boris
Published: July 2015

The present work results in a ready-to-use adsorbent based on MWCNTs and provides a fully validated protocol for determination of PCBs in aqueous environments.
A family of low molecular-weight, organic catalysts for reductive C–C bond formation
Authors: Shaaban Saad , Jolit Anaïs , Petkova Desislava , Maulide Nuno
Published: July 2015

Using only small amounts of a hydrazine catalyst, the coupling of diazonium salts to a variety of reactive partners has been achieved, without the requirement for either metal adjuvants or irradiation with visible or ultraviolet light.
A highly enantioselective Mannich reaction of aldehydes with cyclic N-acyliminium ions by synergistic catalysis
Authors: Berti Francesco , Malossi Federico , Marchetti Fabio , Pineschi Mauro
Published: July 2015

A novel enantioselective synthesis of carbamoyl isoquinoline and tetrahydropyridine derivatives is accomplished using matched combinations of Lewis or Brønsted acids and secondary amine organocatalysts.
One-pot in situ redox synthesis of hexacyanoferrate/conductive polymer hybrids as lithium-ion battery cathodes
Authors: Wong Min Hao , Zhang Zixuan , Yang Xianfeng , Chen Xiaojun , Ying Jackie Y.
Published: July 2015

An efficient and adaptable method is demonstrated for the synthesis of lithium hexacyanoferrate/conductive polymer hybrids for Li-ion battery cathodes.
Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes
Authors: Beebe Alexander W. , Dohmeier Emma F. , Moura-Letts Gustavo
Published: July 2015

Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamineO-sulfonic acid (HOSA). This method provides a wide variety of substituted diaziridines with high yields and diastereoselectivities.
Evidence for a zwitterionic transition state in double bond rotations within tungsten–vinyl complexes
Authors: Gonsales S. A. , Pascualini M. E. , Ghiviriga I. , Veige A. S.
Published: July 2015

Compelling evidence from both experiment and computations point toward a zwitterionic transition state in M–CC double bond rotation.
Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models
Authors: Cavasotto Claudio N. , Palomba Damián
Published: July 2015

We show the key role of structural homology models in GPCR structure-based lead discovery and optimization, highlighting methodological aspects, recent progress and future directions.
Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ3-amino acids
Authors: Aitken Lewis S. , Hammond Lisa E. , Sundaram Rajkumar , Shankland Kenneth , Brown Geoffrey D. , Cobb Alexander J. A.
Published: July 2015

A novel hydroquinine derived organocatalyst has been used to make cyclopropanes useful in the construction of δ3-amino acids.
Crystallographic transformation of limestone during calcination under CO2
Authors: Valverde Jose Manuel , Medina Santiago
Published: July 2015

The calcination of limestone under CO2 is determined by a topotactic transformation.
Manipulating the reaction path of the CO2hydrogenation reaction in molecular sieves
Authors: Borgschulte A. , Callini E. , Stadie N. , Arroyo Y. , Rossell M. D. , Erni R. , Geerlings H. , Züttel A. , Ferri D.
Published: July 2015

We demonstrate that the kinetics of the Sabatier reaction catalysed by sorption catalysts depends on the nanostructure of the catalyst–sorbent system, and in particular on the shape selectivity of the zeolite sorbent.
One-pot reductive amination of aldehydes with nitroarenes over an Au/Al2O3 catalyst in a continuous flow reactor
Authors: Artiukha E. A. , Nuzhdin A. L. , Bukhtiyarova G. A. , Zaytsev S. Yu. , Plyusnin P. E. , Shubin Yu. V. , Bukhtiyarov V. I.
Published: July 2015

Various secondary aromatic amines were synthesized by Au/Al2O3-catalyzed one-pot reductive amination of aldehydes with nitroarenes in a flow reactor.
Evaluation of exposure to organophosphate, carbamate, phenoxy acid, and chlorophenol pesticides in pregnant women from 10 Caribbean countries
Authors: Forde Martin S. , Robertson Lyndon , Laouan Sidi Elhadji A. , Côté Suzanne , Gaudreau Eric , Drescher Olivia , Ayotte Pierre
Published: July 2015

Pesticides are commonly used in tropical regions such as the Caribbean for both household and agricultural purposes.
Microfluidic desalination techniques and their potential applications
Authors: Roelofs S. H. , van den Berg A. , Odijk M.
Published: July 2015

In this review we discuss recent developments in the emerging research field of miniaturized desalination.
A microfluidic device with focusing and spacing control for resistance-based sorting of droplets and cells
Authors: Sajeesh P. , Manasi S. , Doble M. , Sen A. K.
Published: July 2015

We report a novel hydrodynamic technique for sorting of droplets and cells based on size and deformability.
Synthesis and antimicrobial potential of nitrofuran–triazole congeners
Authors: Kamal Ahmed , Hussaini S. M. Ali , Sucharitha M. Lakshmi , Poornachandra Y. , Sultana Faria , Ganesh Kumar C.
Published: July 2015

A series of nitrofuran-triazole congeners were synthesized that displayed excellent to appreciable antimicrobial and antibiofilm activities. Compound 9f inhibited CYP51, an enzyme involved in ergosterol biosynthesis in fungi.
Strong emission of 2,4,6-triphenylpyridine-functionalized polytyrosine and hydrogen-bonding interactions with poly(4-vinylpyridine)
Authors: Mohamed Mohamed Gamal , Lu Fang-Hsien , Hong Jin-Long , Kuo Shiao-Wei
Published: July 2015

The emission intensity of Pyridine-PTyr decreased after blending with P4VP and underwent a hypsochromic shift from 536 to 489 nm due to the release of the restricted intramolecular rotation of the triphenyl pyridine unit in the center of the polymer.
Aerobic photooxidative synthesis of 2-aryl-4-quinazolinones from aromatic aldehydes and aminobenzamide using catalytic amounts of molecular iodine
Authors: Nagasawa Y. , Matsusaki Y. , Nobuta T. , Tada N. , Miura T. , Itoh A.
Published: July 2015

This study reports a safe, mild, and environmentally benign synthetic method toward 2-aryl-4-quinazolinones through a cyclization–oxidation sequence using a catalytic amount of iodine, harmless visible light irradiation, and molecular oxygen.
Novel 3-substituted fluorine imidazolium/triazolium salt derivatives: synthesis and antitumor activity
Authors: Liu Jin-Mei , Wang Min , Zhou Yun-Jing , Yan Ju-Ming , Yang Li-Juan , Li Yan , Zhang Hong-Bin , Yang Xiao-Dong
Published: July 2015

A series of novel (±)-3-substituted fluorene–imidazolium/triazolium salt derivatives were synthesized and their antitumor structure–activity relationship studies were reported.
Novel flame retardant flexible polyurethane foam: plasma induced graft-polymerization of phosphonates
Authors: Jimenez Maude , Lesaffre Nicolas , Bellayer Séverine , Dupretz Renaud , Vandenbossche Marianne , Duquesne Sophie , Bourbigot Serge
Published: July 2015

Flame retardancy of flexible polyurethane foams has become an issue due to very severe regulations.
Enhancing visible light photocatalytic activity of BiOBr/rod-like BiPO4 through a heterojunction by a two-step method
Authors: Dong Hongjie , Cao Zhenzhu , Shao Ruyi , Xiao Yang , He Weiyan , Gao Yanfang , Liu Jinrong
Published: July 2015

Visible light driven BiOBr/rod-like BiPO4 composites with different BiOBr to BiPO4 molar ratios were fabricated via a facile deposition-precipitation method.
Composition-dependent association behavior in the mixture of isopropanol and trichloromethane: a volumetric, vibration spectroscopic and quantum chemical study
Authors: Zhang Yu-Feng , Huang Rong-Yi , Wang Jun-Wei , Kong Xue-Jun
Published: July 2015

Herein the intermolecular associative behaviors in the binary mixture of isopropanol and trichloromethane have been studiedviaa combined excess volumetric, vibration spectroscopic and quantum chemical approach.
A cathodic luminol-based electrochemiluminescence biosensor for detecting cholesterol using 3D-MoS2–PANI nanoflowers and Ag nanocubes for signal enhancement
Authors: Ou Xin , Tan Xingrong , Liu Xiaofang , Chen Hongmei , Fan Yu , Chen Shihong , Wei Shaping
Published: July 2015

The illustration of the synthetic process of 3D-MoS2–PANI–AgNCs nanocomposites and the preparation of an ECL biosensor.
A systematic understanding of gelation self-assembly: solvophobically assisted supramolecular gelation via conformational reorientation across amide functionality on a hydrophobically modulated dipeptide based ambidextrous gelator, N-n-acyl-(l)Val-X(OBn), (X = 1,ω-amino acid)
Authors: Haldar Saubhik , Karmakar Koninika
Published: July 2015

Gelator backbone conformational flexibility plays an important role in a supramolecular self-assembly which is synergistically assisted by solvophobic interaction leading to a gelation of three sets of hydrophobically modulated dipeptidic gelators.
Preparation of supported core–shell structured Pd@PdxSy/C catalysts for use in selective reductive alkylation reaction
Authors: Zhang Qunfeng , Feng Feng , Su Chang , Xu Wei , Ma Lei , Lu Chunshan , Li Xiaonian
Published: July 2015

Supported noble-metal sulphide catalysts have attracted extensive scientific interest for their good selectivity in selective hydrogenation.
Ion-modulated flow behavior of layer-by-layer fabricated polymer thin films
Authors: Liu Xianghua , Gong Xiao , Hu Qiulong , Li Yiwen
Published: July 2015

Flow behavior of polymer thin films which can be facilely tuned by ions is reported.
Electrospun nanofibers incorporating self-decomposable silica nanoparticles as carriers for controlled delivery of anticancer drug
Authors: Zhou Xiaojun , Chen Liang , Wang Weizhong , Jia Yating , Chang Anni , Mo Xiumei , Wang Hongsheng , He Chuanglong
Published: July 2015

A decomposable silica nanoparticle-incorporated electrospun mat as a carrier for anticancer drugs.
A straightforward and “green” solvothermal synthesis of Al doped zinc oxide plasmonic nanocrystals and piezoresistive elastomer nanocomposite
Authors: Šutka Andris , Timusk Martin , Döbelin Nicola , Pärna Rainer , Visnapuu Meeri , Joost Urmas , Käämbre Tanel , Kisand Vambola , Saal Kristjan , Knite Maris
Published: July 2015

Ethanol solvothermal method derives plasmonic Al doped ZnO nanocrystals suitable for advanced applications.
Liquid crystal alignment behavior on sulfonated poly(arylene ether sulfone) films
Authors: Kang Hyo , Kim Kihyun , Kang Daeseung , Lee Jong-Chan
Published: July 2015

A series of sulfonated poly(arylene ether sulfone) (PAES#, # is the feed monomer ratio of 3,3′-disulfonate-4,4′-dichlorodiphenylsulfone) derivatives were synthesized to investigate the liquid crystal (LC) alignment property of these polymer films.
Anti-microbial efficiency of nano silver–silica modified geopolymer mortar for eco-friendly green construction technology
Authors: Adak Dibyendu , Sarkar Manas , Maiti Moumita , Tamang Abiral , Mandal Saroj , Chattopadhyay Brajadulal
Published: July 2015

Schematic representation of the anti-bacterial action of silver–silica modified geopolymer mortar for green construction technology.
Enhanced self-assembled monolayer treatment on polymeric gate dielectrics with ultraviolet/ozone assistance in organic thin film transistors
Authors: Yan Yan , Zhou Ye , Huang Long-Biao , Han Su-Ting , Zhou Li , Xu Zong-Xiang , Roy V. A. L.
Published: July 2015

Chemical vapor deposition (CVD) is utilized to form self-assembled monolayers on polymeric insulators. Ultraviolet/ozone (UVO) treatment is used to enhance the alignment of HMDS monolayer on polymeric insulator surface and a time dependent effect is observed for UVO.
Chitin based hybrid composites reinforced with graphene derivatives: a nanoscale study
Authors: González Joaquín Antonio , Villanueva María Emilia , Peralta Ramos María Luz , Pérez Claudio Javier , Piehl Lidia Leonor , Copello Guillermo Javier
Published: July 2015

Two hybrid materials composed by chitin and nGO/rGO were obtained. nGO acts as a more efficient reinforcer than rGO due to the higher amount of hydrogen bondings established with chitin.
Correction: Paper-based molecular diagnostic for Chlamydia trachomatis
Authors: Linnes Jacqueline C. , Fan Andy , Rodriguez Natalia M. , Lemieux Bertrand , Kong Huimin , Klapperich Catherine M.
Published: July 2015

Correction for ‘Paper-based molecular diagnostic for Chlamydia trachomatis’ by Jacqueline C. Linnes et al., RSC Adv., 2014, 4, 42245–42251.
Correction: Determination of midodrine hydrochloride via Hantzsch condensation reaction: a factorial design based spectrophotometric approach
Authors: Elazazy Marwa S.
Published: July 2015

Correction for ‘Determination of midodrine hydrochloride via Hantzsch condensation reaction: a factorial design based spectrophotometric approach’ by Marwa S. Elazazy et al., RSC Adv., 2015, 5, 48474–48483.
Self-assembly of the decagonal quasicrystalline order in simple three-dimensional systems
Authors: Ryltsev Roman , Klumov Boris , Chtchelkatchev Nikolay
Published: July 2015

Using molecular dynamics simulations we show that a one-component system with purely repulsive two-length-scale potential can form decagonal quasicrystals.
Magnetophoresis of superparamagnetic nanoparticles at low field gradient: hydrodynamic effect
Authors: Leong Sim Siong , Ahmad Zainal , Lim JitKang
Published: July 2015

Experimental and theoretical studies on the nanoparticle-fluid interaction for controlling the low gradient magnetophoresis of magnetic nanoparticles.
Three dimensional architecture of carbon wrapped multilayer Na3V2O2(PO4)2F nanocubes embedded in graphene for improved sodium ion batteries
Authors: Jin Hongyun , Dong Jie , Uchaker Evan , Zhang Qifeng , Zhou Xuezhe , Hou Shuen , Li Jiangyu , Cao Guozhong
Published: July 2015

A novel Na3V2O2(PO4)2F@carbon/graphene three dimensional (3D)architecture (NVPF@C/G) is developed through a simple approach for the first time, which demonstrates superior sodiation properties for Na-ion batteries.
Enhanced thermoelectric performance of porous magnesium tin silicide prepared using pressure-less spark plasma sintering
Authors: Ning Huanpo , Mastrorillo Gioacchino Dario , Grasso Salvatore , Du Baoli , Mori Takao , Hu Chunfeng , Xu Ya , Simpson Kevin , Maizza Giovanni , Reece Michael J.
Published: July 2015

The porous Mg2(Si, Sn) sample pressure-lessly sintered at 1123 K by SPS with a porosity of 37% showed an enhanced maximum zT = 1.63 at 615 K.
A low-cost, ligand exchange-free strategy to synthesize large-grained Cu2ZnSnS4 thin-films without a fine-grain underlayer from nanocrystals
Authors: Huang Tang Jiao , Yin Xuesong , Tang Chunhua , Qi Guojun , Gong Hao
Published: July 2015

Cu2ZnSnS4 nanocrystals without long hydrocarbon chain organic ligands are synthesized directly in a formamide solvent system. Annealing compacted nanocrystal films forms large-grained Cu2ZnSnS4 thin-films without an unwanted fine-grain underlayer.
MoP is a novel, noble-metal-free cocatalyst for enhanced photocatalytic hydrogen production from water under visible light
Authors: Yue Qiudi , Wan Yangyang , Sun Zijun , Wu Xiaojun , Yuan Yupeng , Du Pingwu
Published: July 2015

The present study shows that MoP is a stable and highly active cocatalyst to promote photocatalytic H2 production from water when attached on the semiconductor surface.
Azopolymer triggered electrophoretic deposition of MnO2-carbon nanotube composites and polypyrrole coated carbon nanotubes for supercapacitors
Authors: Liu Yangshuai , Shi Kaiyuan , Zhitomirsky Igor
Published: July 2015

MnO2 nanofibers-multiwalled carbon nanotube composites and polypyrrole coated carbon nanotubes for supercapacitors were prepared by new chemical and electrochemical methods.
Robust, anti-fatigue, and self-healing graphene oxide/hydrophobically associated composite hydrogels and their use as recyclable adsorbents for dye wastewater treatment
Authors: Cui Wei , Ji Jin , Cai Yi-Feng , Li Hang , Ran Rong
Published: July 2015

Illustration of a self-healing, anti-fatigue GHA gel being applied as a recyclable adsorbent for dye wastewater treatment.
HxMoO3−ynanobelts with sea water as electrolyte for high-performance pseudocapacitors and desalination devices
Authors: Huang Liang , Gao Xiang , Dong Qiang , Hu Zhimi , Xiao Xu , Li Tianqi , Cheng Yongliang , Yao Bin , Wan Jun , Ding Dong , Ling Zheng , Qiu Jieshan , Zhou Jun
Published: July 2015

Pseudocapacitors, which store charge through fast reversible redox reactions occuring at the surface of the electrode, could offer a higher specific capacitance than electrochemical double-layer capacitors (EDLCs).
Effects of the molecular weight and the valency of guest-modified poly(ethylene glycol)s on the stability, size and dynamics of supramolecular nanoparticles
Authors: Stoffelen Carmen , Staltari-Ferraro Eugenio , Huskens Jurriaan
Published: July 2015

The length and valency of PEG-based stopper molecules have a pronounced effect on the self-assembly, size, stability and dynamics of supramolecular nanoparticles.
Smectogenic liquid crystals and nanoparticles: an approach for potential application in photovoltaics
Authors: Meneses-Franco A. , Fierro-Armijo A. E. , Romero-Hasler P. , Salamanca-Riba L. G. , Martínez-Miranda L. J. , Soto-Bustamante E. A.
Published: July 2015

We synthesized monomeric liquid crystals, M6R8 and I6R8, and nanoparticles of TiO2, to form a nanocomposite, which was characterized by polarized optical microscopy (POM), DSC and structurally with both wide angle X-ray diffraction and by X-ray scattering using the planar geometry.