bluuebunny/crossref_metadata_2025 huggingface dataset:
APO Time-resolved Color Photometry of Highly Elongated Interstellar Object 1I/‘Oumuamua
Authors: Bolin Bryce T. , Weaver Harold A. , Fernandez Yanga R. , Lisse Carey M. , Huppenkothen Daniela , Jones R. Lynne , Jurić Mario , Moeyens Joachim , Schambeau Charles A. , Slater Colin. T. , Ivezić Željko , Connolly Andrew J.
Published: December 2017

We report on g-, r-, and i-band observations of the Interstellar Object 1I/‘Oumuamua (1I) taken on 2017 October 29 from 04:28 to 08:40 UTC by the Apache Point Observatory (APO) 3.5 m telescope’s ARCTIC camera. We find that 1I’s colors are

and

, consistent with visible spectra and most comparable to the population of solar system C/D asteroids, Trojans, or comets. We find no evidence of any cometary activity at a heliocentric distance of 1.46 au, approximately 1.5 months after 1I’s closest approach distance to the Sun. Significant brightness variability was seen in the r observations, with the object becoming notably brighter toward the end of the run. By combining our APO photometric time series data with the Discovery Channel Telescope data of Knight et al., taken 20 hr later on 2017 October 30, we construct an almost complete lightcurve with a most probable single-peaked lightcurve period of

. Our results imply a double-peaked rotation period of 8.1 ± 0.02 hr, with a peak-to-trough amplitude of 1.5–2.1 mag. Assuming that 1I’s shape can be approximated by an ellipsoid, the amplitude constraint implies that 1I has an axial ratio of 3.5–10.3, which is strikingly elongated. Assuming that 1I is rotating above its critical break up limit, our results are compatible with 1I having modest cohesive strength and may have obtained its elongated shape during a tidal distortion event before being ejected from its home system.
Aphyllophoroid fungi in insular woodlands of eastern Ukraine
Authors: Ordynets Alexander , Savchenko Anton , Akulov Alexander , Yurchenko Eugene , Malysheva Vera , Kõljalg Urmas , Vlasák Josef , Larsson Karl-Henrik , Langer Ewald
Published: December 2017

Fungi play crucial roles in ecosystems and are among the species-richest organism groups on Earth. However, knowledge on their occurrence lags behind the data for animals and plants. Recent analyses of fungal occurrence data from Western, Central and Northern Europe provided important insights into response of fungi to global warming. The consequences of the global changes for biodiversity on a larger geographical scale are not yet understood. Landscapes of Eastern Europe and particularly of eastern Ukraine, with their specific geological history, vegetation and climate, can add substantially new information about fungal diversity in Europe.

We describe the dataset and provide a checklist of aphyllophoroid fungi (non-gilled macroscopic Basidiomycota) from eastern Ukraine sampled in 16 areas between 2007 and 2011. The dataset was managed on the PlutoF biodiversity workbench (http://dx.doi.org/10.15156/BIO/587471) and can also be accessed via Global Biodiversity Information Facility (GBIF, parts of datasets https://doi.org/10.15468/kuspj6 and https://doi.org/10.15468/h7qtfd). This dataset includes 3418 occurences, namely 2727 specimens and 691 observations of fructifications belonging to 349 species of fungi. With these data, the digitised CWU herbarium (V. N. Karazin Kharkiv National University, Ukraine) doubled in size A most detailed description of the substrate's properties and habitat for each record is provided. The specimen records are supplemented by 26 nuclear ribosomal DNA ITS sequences and six 28S sequences. Additionally, 287 photographs depicting diagnostic macro- and microscopic features of fungal fruitbodies as well as studied habitats are linked to the dataset. Most of the specimens have at least one mention in literature and relevant references are displayed as associated with specimen data. In total, 16 publication references are linked to the dataset. The dataset sheds new light on the fungal diversity of Eastern Europe. It is expected to complement other public sources of fungal occurrence information on continental and global levels in addressing macroecological and biogeographical questions.
Controlling Immigrant Integration in the Euro-Mediterranean Region: A Compelling Turnaround in Times of Economic Crisis
Authors: Spina Encarnación La
Published: December 2017

The Euro­‑Mediterranean region has become one of the most critical areas in the European Union on the issue of attracting migrants and experiencing the subsequent migratory pressures, but this has had very little impact on major comparative studies of European integration policies. Greece, Italy, Spain and Portugal are easily identifiable as exponents of a ‘non-model’ system of integration. This trend changed on an academic and political level in the period from 2003 to 2009. Southern European countries have yet to establish nationwide integration policies for immigrants, and in times of economic crisis they have strongly restricted welfare protection, even though social rights are keystones for immigrant integration. Looking mainly at the Euro-Mediterranean region, this paper aims to analyse crossed interactions, to detect strengths, weaknesses, opportunities and threats in the emulation of nationalistic models in order to boost immigrant integration through equal access to social rights.
Segnalazioni Faunistiche Italiane
Authors: V.V. A.A.
Published: December 2017

Non disponibile
First records of Brachythemis impartita in peninsular Italy (Odonata: Libellulidae)
Authors: Condello Emanuele Guido , Razzetti Edoardo , Liuzzi Cristiano , D’Agostino Vittoria , Mastropasqua Fabio
Published: December 2017

Two populations of Brachythemis impartita (Karsch, 1890) are here reported in peninsular Italy. The species was found for the first time in 2015 in Calabria in the area of the Angitola artificial lake (Maierato and Monterosso Calabro municipalities) not far from the Tyrrhenian coast. In 2016 the species was also observed in southern Apulia, along the banks of two artificial lagoons in the municipality of Ugento. Information are provided that confirm the habitat preferences of the species and a northward expansion.
Ecology and life history of Paratomapoderus brachypterus in Gabon (Coleoptera: Attelabidae)
Authors: Biondi Silvano , Massarone Carlo , Manci Cosmin-Ovidiu
Published: December 2017

On the base of data collected during four expeditions in Gabon (West Africa) from 2012 to 2016, the authors provide new information on trophic activity and reproductive behaviour of Paratomapoderus brachypterus (Voss, 1926) (Attelabidae: Apoderinae, Hoplapoderini), with emphasis on leaf-roll realisation; host plant, leaf roll, larva and pupa are illustrated for the first time.
Nutritional management of preterm newborn after hospital discharge: energy and nutrients
Authors: Villa Elisabetta , Barachetti Roberta , Barbarini Mario
Published: December 2017

Preterm infants are at risk for poor growth while in the Neonatal Intensive Care Unit (NICU) and after discharge from the NICU. The main objective is to reach the body composition and rate of growth of a normal fetus/infant of the same post-menstrual age during the first entire year of life. In case of human milk, the limited data do not provide convincing evidence that feeding preterm infants after discharge with multi-nutrient fortified human milk, compared with unfortified, affects important outcomes including growth rates during infancy. Conversely, if formula-fed, post discharge formulas produce short term advantages in growth rate but no long term advantages are demonstrated. It is very important to establish a feeding plan and a follow up for all preterm babies who are discharged from NICU in order to recognize as soon as possible any growth deficit.
Microvascular damage evaluation in systemic sclerosis: the role of nailfold videocapillaroscopy and laser techniques
Authors: Ruaro B. , Sulli A. , Smith V. , Pizzorni C. , Paolino S. , Alessandri E. , Cutolo M.
Published: December 2017

Microvascular damage and a decrease in peripheral blood perfusion are typical features of systemic sclerosis (SSc) with serious clinical implications, not only for a very early diagnosis, but also for disease progression. Nailfold videocapillaroscopy is a validated and safe imaging technique able to detect peripheral capillary morphology, as well as to classify and to score any nailfold abnormalities into different microangiopathy patterns. Capillaroscopic analysis is now included in the ACR/EULAR classification criteria for SSc. The decrease in peripheral blood perfusion is usually associated with microvascular damage in SSc, which may be studied by different methods. Several of these make use of safe laser technologies. This paper focuses on these new clinical aspects to assess SSc microvascular impairment.
Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study
Authors: Rasheed A.B. , Daoud M.S. , Gorial F.I.
Published: December 2017

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory disease and early diagnosis is of clinical and therapeutic importance. Melatonin is an endogenous endolamine hormone that plays an important role in the immune system due to its anti-inflammatory action. This study was designed to assess serum melatonin levels in SLE patients and to evaluate the possible correlation between serum melatonin and patients’ baseline characteristics. A case-control study was performed on 50 SLE patients (48 females and 2 males), diagnosed according to the revised 1997 ACR Criteria, and 25 healthy controls (24 females and 1 male), matched by age and sex. Daily serum melatonin levels were investigated in all participants using human melatonin enzyme linked immunosorbent assay (ELISA) kit (MYBIOSOURCE (MBS), United States). Serum melatonin concentration was significantly lower in patients with SLE compared to healthy controls (19.17±6.86 pg/mL vs 23.26±6.71 pg/mL, p=0.017). Serum melatonin concentration ≤18.51 pg/mL was the optimum cut off value to differentiate between SLE patients and healthy controls with an accuracy of 69.3%, a sensitivity of 66%, and a specificity of 76%. The positive predictive value (PPV) at pretest 50% was 73.3% and PPV at pretest 90% was 96.1%; the negative predictive value (NPV) at 10% was 95.3%. Patients’ characteristics were not significantly correlated with serum melatonin concentrations using multiple logistic regression analysis. Serum melatonin was a valid measure to differentiate between SLE patients and healthy controls with good accuracy, sensitivity and specificity and PPV and NPV. There was no significant correlation between serum melatonin concentrations and patients’ baseline characteristics.
Analysis of beta-lactamases, bla NDM-1 phylogeny & plasmid replicons in multidrug-resistant Klebsiella spp. from a tertiary care centre in south India
Authors: Nithya N. , Remitha Rabindran , Jayasree P. R. , Faisal M. , Manish Kumar P. R.
Published: December 2017

Background & objectives:

β-lactamases play a predominant role in drug-resistance amongst Enterobacteriaceae. Presence of genes on transferable plasmids encoding these enzymes favours their dissemination across species and genera within and outside geographical boundaries. This study was aimed to understand the presence of β-lactamases and transferable plasmids in clinical isolates of Klebsiella spp. which can contribute to the spread of resistance determinants.

Methods:

A total of 41 clinical isolates of Klebsiella spp., collected from a tertiary care centre in Kerala, India, were checked for antibiotic sensitivity and the presence of plasmids. The ability to produce extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBLs) was screened for and confirmed in 29 plasmid-harbouring isolates. bla
NDM-1-specific primers were used for polymerase chain reaction amplification with plasmid DNA as template to determine episomal prevalence of this gene and its sequence-based phylogeny employing similar sequences from GenBank. Plasmid replicon typing was also carried out to determine the presence of transferable plasmids.

Results:

Our results showed a high degree of multidrug-resistant (MDR) pathogens with ESBL production confirmed in 52 per cent, MBL in 31 per cent and co-production of both enzymes in seven per cent of the plasmid-bearing isolates. Plasmid DNA from 14 per cent of the isolates produced bla
NDM-1-specific amplicons which showed sequence homology with those from bacteria of different genera and geographical areas. The predominant replicon type was found to be that of conjugative plasmids belonging to the incompatibility group - IncFIIK.

Interpretation & conclusions:

This study provides insight into the predominance of various β-lactamases and potent gene-disseminating agents in Klebsiella spp. and emphasizes the need for constant surveillance of these pathogens to determine appropriate treatment strategies.
Speciation, clinical profile & antibiotic resistance in Aeromonas species isolated from cholera-like illnesses in a tertiary care hospital in north India
Authors: Mohan Balvinder , Sethuraman Nandini , Verma Ritu , Taneja Neelam
Published: December 2017

Background & objectives:

Aeromonas species have been reported to cause various illnesses in humans such as wound infections, septicaemia, peritonitis and pneumonia. Their role in causation of cholera-like illness is also being increasingly recognized. This retrospective study was done to know the presence of Aeromonas as a cause of acute diarrhoea in a tertiary care hospital and to find the common species of Aeromonas causing diarrhoea and their antibiotic susceptibility patterns.

Methods:

Fifty isolates of Aeromonas were obtained over a period of 15 yr from 2000 to 2014 from patients of suspected acute gastroenteritis resembling cholera. Biotyping was done for 35 of these isolates available in culture collection, based on a panel of 13 biochemical reactions. Antibiogram was put up for all of these isolates by disk diffusion methods and interpreted according to the Clinical and Laboratory Standards Institute guidelines.

Results:

Of the 50 patients of Aeromonas-related acute gastroenteritis, 13 (26%) had typical features of cholera with rice water stools and severe dehydration. Eight patients (16%) had dysentery-like picture. One patient died of severe dehydration and septicaemia. The most common species were found to be Aeromonas caviae (34%) followed by Aeromonas veronii biovar veronii (29%), Aeromonas veronii biovar sobria (26%) and Aeromonas hydrophila (9%). All tested isolates were uniformly susceptible to cefepime, amikacin, azithromycin and meropenem; 14 per cent were susceptible to amoxicillin, 32 per cent to nalidixic acid, 60 per cent to co-trimoxazole, 54 per cent to ciprofloxacin, 60 per cent to ofloxacin, 74 per cent to chloramphenicol, 76 per cent to ceftriaxone, 74 per cent to cefotaxime, 88 per cent to gentamicin and 86 per cent to furoxone.

Interpretation & conclusions:

Aeromonas is an important, often neglected pathogen capable of causing a variety of gastrointestinal tract symptoms such as acute diarrhoea and dysentery and may even mimic cholera. It is, therefore, pertinent to recognize this pathogen as an important agent in the causation of severe diarrhoea.
Staphylococcus aureus biofilm removal by targeting biofilm-associated extracellular proteins
Authors: Shukla Sudhir K. , Rao T. Subba
Published: December 2017

Background & objectives:

Among cell surface proteins, biofilm-associated protein (Bap) promotes biofilm development in Staphylococcus aureus strains. The aim of this study was to investigate proteinase-mediated biofilm dispersion in different isolates of S. aureus.

Methods:

Biofilm assay was done in 96-well microtitre plate to evaluate the effect of proteinase K on biofilms of bovine mastitis S. Aureus isolates. Extracellular polymeric substances were extracted and evaluated for their composition (protein, polysaccharides and extracellular DNA), before and after the proteinase K treatment.

Results:

Biofilm assay showed that 2 µg/ml proteinase K significantly inhibited biofilm development in bap-positive S. aureus V329 as well as other S. aureus isolates (SA7, SA10, SA33, SA352), but not in bap-mutant M556 and SA392 (a weak biofilm-producing strain). Proteinase K treatment on S. aureus planktonic cells showed that there was no inhibition of planktonic growth up to 32 µg/ml of proteinase K. Proteinase K treatment on 24 h old preformed biofilms showed an enhanced dispersion of bap-positive V329 and SA7, SA10, SA33 and SA352 biofilms; however, proteinase K did not affect the bap-mutant S. aureus M556 and SA392 biofilms. Biofilm compositions study before and after proteinase K treatment indicated that Bap might also be involved in eDNA retention in the biofilm matrix that aids in biofilm stability. When proteinase K was used in combination with antibiotics, a synergistic effect in antibiotic efficacy was observed against all biofilm-forming S. aureus isolates.

Interpretation & conclusions:

Proteinase K inhibited biofilms growth in S. aureus bovine mastitis isolates but did not affect their planktonic growth. An enhanced dispersion of preformed S. aureus biofilms was observed on proteinase K treatment. Proteinase K treatment with antibiotics showed a synergistic effect against S. aureus biofilms. The study suggests that dispersing S. aureus by protease can be of use while devising strategies against S. aureus biofilms.
Detection of Chlamydia trachomatis infections by polymerase chain reaction in asymptomatic pregnant women with special reference to the utility of the pooling of urine specimens
Authors: Sethi Sunil , Roy Amit , Garg Shubha , Venkatesan Lakshmi Sree , Bagga Rashmi
Published: December 2017

Background & objectives:

Genital Chlamydia trachomatis (CT) infections are one of the most prevalent sexually transmitted infections across the world. In pregnant women, if not detected and treated early, these may result in poor pregnancy outcomes and complications. The present study was aimed to screen CT infections from first void urine (FVU) samples of asymptomatic pregnant women using molecular methods. The secondary objective was to evaluate cost-effectiveness in pooling FVU samples for their diagnostic application.

Methods:

FVU samples were collected from 1000 asymptomatic pregnant women over a period of three years. Pooling was done by including five specimens in one pool in the amount of 10 µl and subjected to polymerase chain reaction (PCR) and further confirmed by direct fluorescent antibody assay (DFA).

Results:

The age of study participants ranged from 18 to 43 yr with the median±standard deviation of 26±3.84 yr. Majority of positive participants were younger than 25 years. A total of 200 pools were prepared and 20 of these were PCR positive. When individual specimen in 20 positive pools was tested, 20 PCR-positive specimens were identified from 19 pools, of which 16 were positive by DFA. Thus, CT was detected in 1.6 per cent asymptomatic pregnant women in India and pooling strategy resulted in 70 per cent reduction in a number of tests performed.

Interpretation & conclusions:

Our study detected C. trachomatis infection in 1.6 per cent asymptomatic pregnant women, and pooling of FVU specimens for PCR testing was found to be a cost-saving strategy in comparison to testing individual samples. Further evaluation and studies on the bigger sample size are warranted to validate these results.
Protocol: Systematic Literature Review on coordination mechanisms for the mathematical programming models in production planning with decentralized decision making
Authors: Rius-Sorolla Gregorio , Maheut Julien , Estelles-Miguel Sofía , Garcia-Sabater José Pedro
Published: December 2017

The article presents the research protocol for a systematic literature review on the coordination mechanisms in the mathematical programming for decentralized decision making on the planning and scheduling, intra or inter companies from 2006 to 2016.

[Protocolo:revisión sistemática de literatura sobre los mecanismos de coordi-nación en los modelos de programación matemática para la toma de decisio-nes descentralizadas.

El artículo presenta el protocolo de investigación para la realización de una revisión sis-temática sobre los mecanismos de coordinación en los modelos de programación matemá-tica, para la toma de decisiones descentralizadas sobre la planificación y la programa-ción de la producción, entre plantas de la misma empresa o entre plantas de diferentes empresas, en el periodo de 2006 a 2016.
Impacts of the Horizontal and Vertical Grids on the Numerical Solutions of the Dynamical Equations. Part II: Quasi-Geostrophic Rossby Modes
Authors: Konor Celal S , Randall David A.
Published: December 2017

Abstract. We use a normal-mode analysis to investigate the impacts of the horizontal and vertical discretizations on the numerical solutions of the quasi-geostrophic anelastic baroclinic and barotropic Rossby modes on a midlatitude β-plane. The dispersion equations are derived for the linearized anelastic system, discretized on the Z, C, D, CD, (DC), A, E, and B horizontal grids, and on the L and CP vertical grids. The effects of various horizontal grid spacings and vertical wave numbers are discussed. A companion paper, Part I, discusses the impacts of the discretization on the inertia-gravity modes on a midlatitude f-plane. The results of our normal-mode analyses for the Rossby waves overall support the conclusions of the previous studies obtained with the shallow-water equations. We identify an area of disagreement with the E-grid solution.
APARATO CONCEITUAL SOBRE ÁREAS ÚMIDAS (WETLANDS) NO BRASIL: DESAFIOS E OPINIÕES DE ESPECIALISTAS
Authors: Siman Gomes Cecília , Pereira Magalhães Junior Antônio
Published: December 2017

As Áreas úmidas (AUs) são ecossistemas complexos, integradas por variáveis hidrológicas, climáticas, geomorfológicas, pedológicas e bioquímicas, que desempenham funções ambientais relevantes. A complexidade encontrada nos estudos das AUs explica a dificuldade de estabelecer consensos na sua definição, tanto no meio científico quanto jurídico. No Brasil, ainda são poucos os estudos que buscam investigar as AUs sob o ponto de vista conceitual, o que causa problemas na concepção e aplicação da legislação referente à sua proteção. A visão do geógrafo, horizontalizada e multidisciplinar, é potencialmente útil para as pesquisas sobre AUs. Neste contexto, esta pesquisa teve por objetivo desenvolver uma proposta conceitual de referência, visando melhorar a compreensão do conceito e facilitar a sua aplicação. No desenvolvimento dessa proposta, foi realizada uma investigação e análise teórico-reflexiva das definições presentes na literatura científica e nos dispositivos legais, nacionais e internacionais, complementada e articulada com opiniões imprescindíveis de especialistas em AUs. A proposta resultou em uma síntese conceitual que inclui características relativas à formação, identificação e delimitação das AUs, para visar a maiores concordâncias por pesquisadores, analistas, técnicos e gestores de diferentes áreas do conhecimento e sua aplicação na área ambiental.Palavras-chave: Áreas úmidas, ecossistemas, hidrogeomorfologia.
“Traje: um objeto de arte?”: Pietro Maria Bardi, o wearable art e o museu fora dos limites
Authors: Bonadio Maria Claudia
Published: December 2017

Neste artigo analiso a importância da exposição Traje: um objeto de arte? realizada no Museu de Arte de São Paulo em 1987, como parte do projeto de integração entre arte e moda, que foi defendido por Pietro Maria Bardi, diretor do Museu na época. AbstractThis article analyzes the importance of the exhibition Dress: an object of art? held in the São Paulo Art Museum in 1987, as part of the project of integration between art and fashion proposed by Pietro Maria Bardi, then director of the Museum at that year. ResumenEn este artículo analizo la importancia de la exposición Traje: un objeto de arte? que se realizó en el Museo de Arte de São Paulo en 1987, como parte del proyecto de integración entre arte y moda, que fue defendido por Pietro Maria Bardi, director del Museo en la época.
The Critical Role of the Clinical Research Coordinator for Clinical Trials: A Survey in Oncology
Authors: Cinefra Margherita , Cagnazzo Celeste , McMahon Laura , Arizio Francesca , Campora Sara , Camisa Roberta , Canzanella Giuliana , Contu Marianna , Frati Paola , Sottile Roberta , Gori Stefania , Procopio Giuseppe , Nanni Oriana ,   on behalf of the AIOM Working Group Coordinatori di Ricerca Clinica
Published: December 2017

Introduction

Access to innovative medicine requires proper evidence from clinical trials with the growing demand of qualified and experienced personnel. The clinical research coordinator (CRC) plays an important role in the conduction of research activities and provides a strong support to the research team. In Italy, this role is not recognized at any institutional level and its professional outline is still indefinite. Several national associations (Associazione Italiana di Oncologia Medica, Collegio Italiano dei Primari Oncologi Medici Ospedalieri, Gruppo Italiano Data Manager) are committed to promoting the enhancement and recognition of the professional status of CRCs, underlining their role as fundamental.

Methods

A web survey, proposed by the AIOM CRC Working Group, was submitted to 319 Italian oncology sites with items focusing on the organization of sites, the research activities, the staff composition, and the presence of coordinators and the multidisciplinary team.

Results

A total of 115 sites (35.9%) responded to the web survey. Clinical studies were carried out at 88.7% of the investigated sites, and coordinators were on staff at 75.5% of the active investigational sites. Interestingly, there was a direct association between the number of clinical studies and the number of coordinators, whose contribution to the research activities is believed to be essential for trial conduct in 82.4% of cases. Most sites retain that the quality of clinical research has absolutely improved (83.3%) after the implementation of a coordinator as member of the team.

Conclusions

Given the constant growth of the number of clinical trials performed at Italian oncology sites, the CRC proves to be an essential component of the research team. However, there is an urgent need to institute the professional role alongside the need to standardize the training of coordinators to establish the minimum requirements enhanced by qualifying courses.
La relevancia de la investigación durante la formación de pregrado
Authors: Arévalo Ana Carolina , Medina Ligia
Published: December 2017

Sin resumen disponible.
Análisis gravitrópico de la raíz primordial de plantas mesoamericanas, en condiciones de microgravedad simulada
Authors: Medina Brenda , Rodríguez Cesar
Published: December 2017

Esta investigación muestra datos del crecimiento y curvatura gravitrópica de seis especies de importancia actual para el área Mesoamericana, Paseolus vulgaris var. Criolla, Paseolus vulgaris var. Amadeus 77, Phaseolus lunatus Phaseolus acutifolious, Vigna unguiculata y Sorghum bicolor; bajo condiciones de microgravedad simulada en clinostato de un eje, así como cortes histológicos de los tejidos de las muestras clinorotadas y las muestras Control 1g.Tiene como objetivo comprender el comportamiento de la raíz primordial de plantas actualmente cultivadas en Mesoamérica, cuando la fuerza neta sobre la vertical es menor que la fuerza gravitacional; Esto con la intención de identificar las especies vegetales que pudieran tener un crecimiento óptimo a baja gravedad.Las pruebas de laboratorio se llevaron a cabo en las instalaciones de la Facultad de Ciencias Espaciales UNAH. Sembrando en discos de Petri con un sustrato llamado agar y dentro de cámaras húmedas para mantener iguales condiciones de humedad y temperatura. Luego de germinadas las raíces se procedió al proceso de clinorotación de la muestra llamada “Clinorotada” (sometida a microgravedad) durante sesiones de dos horas; tomando fotografías cada treinta minutos para su posterior análisis de comparación. Los datos fueron analizados mediante el programa ImageJ, y tabulados mediante Excel.Phaseolus lunatus, Vigna unguiculata y Soghum bicolor son tres especies en las que se pudo observar que su crecimiento no ha sido considerablemente afectado a baja gravedad. Por lo que son especies que podrían ser consideradas para mayores estudios en microgravedad a bordo de sondas espaciales.Revista Portal de la Ciencia, No. 12, junio 2017; 73-96
La interdisciplinariedad de las ingenierías, gestión del fortalecimiento de las capacidades en comunidades rurales
Authors: Muñoz Enamorado Diana Mabel , Morales Santos Angela Gabriela , Zorto Aguilera Fernando José
Published: December 2017

Las carreras de ingenierías juegan un rol muy importante en el desarrollo de las comunidades que buscan como resolver sus carencias y falta de recursos. La interdisciplinariedad es una ventaja real en toda la Facultad de Ingeniería de la Universidad Nacional Autónoma de Honduras. Esto tiene como beneficio el poder intervenir desde diversas áreas del conocimiento las problemáticas que existen en las zonas afectadas de una comunidad brindando un apoyo a la gestión de fortalecimiento de las capacidades de los pueblos indígenas en el país. El estudio plantea la manera de crear un modelo de intervención utilizando múltiples enfoques de las diferentes carreras de ingeniería de la UNAH para desarrollar una visión clara en su gestión en el apoyo de las capacidades a Las zonas rurales del país. La investigación hace constar que la integración de las diferentes carreras puede brindar las soluciones necesarias para el fortalecimiento de las capacidades de estas zonas. La ingeniería como área del conocimiento en la UNAH puede definir acciones interdisciplinarias reales para clarificar la gestión de apoyo con las comunidades, estructurando su intervención con base a las áreas disciplinarias para desarrollar actividades y soluciones a la problemática que tienen estas comunidades rurales.Revista Portal de la Ciencia, No. 12, junio 2017; 120-137
La negociación colectiva como mecanismo de mejora de la productividad laboral
Authors: Molina Oscar , Godino Alejandro
Published: December 2017

La negociación colectiva puede tener un papel en la mejora de la productividad laboral a través de diferentes mecanismos. Siendo la variable sectorial clave para entender las dinámicas de las relaciones laborales, se plantea en este artículo un análisis de cuatro sectores de la economía española para observar de qué manera la productividad puede ser resultado de la negociación colectiva.
La brecha salarial y las desigualdades de género en el mercado de trabajo. una revisión de aproximaciones teóricas y aportaciones empíricas
Authors: Sánchez-Mira Núria
Published: December 2017

Las aproximaciones al análisis de la brecha salarial se han centrado, a menudo, en factores relativos a la lógica interna del mercado de trabajo, tratando de identificar las diferencias objetivables en las posiciones de hombres y mujeres en el empleo, que dieran cuenta de la distancia entre sus remuneraciones. Unas diferencias que, lejos de analizarse como dadas, deben verse como incrustadas en una estructura y organización socioeconómica que segrega a ambos géneros en distintas posiciones, espacios y tiempos sociales, y que, en concreto, sitúa a las mujeres en una posición subordinada en la esfera del mercado de trabajo; bien porque se emplean en sectores feminizados e infravalorados, bien porque la mayor disponibilidad masculina para el empleo existe a costa de la mayor presencia femenina en las tareas reproductivas. Es partiendo de este marco general de análisis que se realiza una revisión de las principales aportaciones teóricas y empíricas al estudio de la brecha salarial de género, abordando tres ejes principales: las desigualdades en el tiempo de trabajo remunerado, la minusvaloración del trabajo realizado por las mujeres, y las barreras a la promoción femenina junto con los sesgos de género en las prácticas de remuneración en las empresas.
Les ressources minérales et végétales de la Cerdagne orientale. Bois, mines, fours à chaux, charbonnières et sites de transformation des minerais. L’apport de l’archéologie.
Authors: Campmajo Pierre , Rendu Christine , Crabol Denis , Bousquet Delphine , Luault Noémie
Published: December 2017

Cet article offre un aperçu de l'exploitation des ressources minérales et végétales de la Cerdagne dans les temps anciens. L'analyse archéologique se concentre sur l'étude de ressources telles que le bois, les mines, les fours de chaux, les charbonnières et les points de transformation des minerais.
Pràctiques ramaderes a la plana de la Cerdanya entre els segles III ane - III ne: més que pernae
Authors: Colominas Barberà Lidia
Published: December 2017

L’article pretén analitzar l’evolució de les pràctiques ramaderes a la plana de la Cerdanya durant l’Antiguitat (segles III ane – III ne). Tot i l’escassetat de les dades disponibles en aquest sentit, les recents intervencions arqueològiques a jaciments com el Castellot de Bolvir, el Tossal de Baltarga de Bellver de Cerdanya o la ciutat romana de Llívia permetent oferir una primera aproximació a com el poble ceretà gestionava els recursos ramaders i quina importància tingueren aquests dins de la seva societat.
L’exploitation antique du cuivre dans le Séronais (Pyrénées centrales, France) Mine, métallurgie et habitat
Authors: Meunier Emmanuelle , Cauuet Béatrice , Munoz Margot
Published: December 2017

Les nouvelles prospections sur le district minier cuprifère du Séronais ont permis de mieux comprendre l’organisation de l’espace en relation avec les mines pour l’époque tardo-républicaine, avec la localisation d’ateliers de traitement du minerai et d’habitats. Mais les datations, réalisées sur des charbons issus des chantiers, ont montré que cette phase avait été précédée par une première exploitation dès les IVe et IIIe s. av. n. è., inconnue jusqu’alors. La reprise médiévale du XIVe s. a également été confirmée. D’autre part, les analyses sur le minerai et les scories permettent de confirmer la production de cuivre de ce district pour l’Antiquité (Ier s. av. n. è.), mais pas de l’argent identifié dans le minerai.
Appréhender les dynamiques agraires dans une région de montagne, la Cerdagne : état des lieux (Antiquité tardive/Haut Moyen Âge)
Authors: Luault Noémie
Published: December 2017

Cet article vise à offrir les premières données d'une étude sur les dynamiques agraires dans la région pyrénéenne de la Cerdagne entre les périodes historiques de l'Antiquité tardive et le Haut Moyen Age. Ces données proviennent d'un ensemble de campagnes d'intervention archéologique dans diverses zones rurales entre des sites de chronologie ancien tels que Coume Païrounell ou Iulia Libica.
Epigenetic determinants in rheumatoid arthritis: the influence of DNA methylation and histone modifications
Authors: Kolarz Bogdan , Majdan Maria
Published: December 2017

Epigenetics is a field of science which describes external and environmental modifications to DNA without altering their primary sequences of nucleotides. Contrary to genetic changes, epigenetic modifications are reversible. The epigenetic changes appear as a result of the influence of external factors, such as diet or stress. Epigenetic mechanisms alter the accessibility of DNA by methylation of DNA or post-translational modifications of histones (acetylation, methylation, phosphorylation, ubiquitinqation). The extent of DNA methylation depends on the balance between DNA methyltransferases and demethylases. The main histone modifications are stimulated by K-acetyltransferases, histone deacetylases, K-metyltransferases and K-demethylases. There is proof that environmental modifications of this enzymes regulate immunological processes including autoimmunity in rheumatoid arthritis (RA). In this work
we present epigenetic mechanisms involved in RA pathogenesis and a range of research presenting
the possible impact of its modification in RA patients.
Letter from the Editor
Authors: Varnum Kenneth J.
Published: December 2017

Letter from the Editor.
Exosomal microRNA remodels the tumor microenvironment
Authors: Jiang Xiaoli , Hu Song , Liu Qiang , Qian Caiyun , Liu Zhuoqi , Luo Daya
Published: December 2017

Tumor occurrence, progression and metastasis depend on the crosstalk between tumor cells and stromal cells and on extrinsic factors outside the tumor microenvironment. Exosomal microRNA (miRNA) not only is involved in communications within the tumor microenvironment but also mediates communications between the extrinsic environment and tumor microenvironment. However, most reviews have been limited to the role of endogenous exosomal miRNA in remodeling the tumor microenvironment. Hence, we herein review the role of endogenous exosomal miRNA in mediating intercellular crosstalk within the tumor microenvironment, inducing the formation of the premetastatic niche. To place our vision outside the microenvironment, we also summarize for the first time the most recent studies regarding how exogenous miRNA derived from milk, plants and microbes influences the tumor microenvironment. Furthermore, to improve the value of exosomal miRNA in cancer research and clinical applications, we also provide some novel ideas for future research based on the comprehensive role of exosomal miRNA in remodeling the tumor microenvironment.
Renewed Estimates of Grassland Aboveground Biomass Showing Drought Impacts
Authors: Li F. , Chen J. Q. , Zeng Y. , Wu B. F. , Zhang X. Q.
Published: December 2017

Variations in ecosystem composition and structure within a cover type of the same biome can be responsible for the large amounts of uncertainty in remote sensing modeling of aboveground biomass (AGB). Based on 820 ground measurements of AGB and the pure vegetation index models, we proposed a spatially variable remote sensing scalar (i.e.,Mscalar) in estimating AGB by addressing within‐type variations of vegetation. We tested this new modeling approach in Inner Mongolia grasslands and achieved a higherR2(>0.88) and lower RMSE value (<28.17 g/m2) than those in the conventional remote sensing models. The annual average (STD) of the grassland AGB for 2001–2016 was ~87 (±9) Tg, with an AGB density of 104 ± 74 g/m2. The interannual variation of AGB appeared insignificant over the study period, except in the western region where it increased significantly. The dynamics of AGB were highly correlated with drought severity during the growing season (R2 = 0.691,P < 0.001). AGB under normal climate (i.e., without drought) was ~90.88 Tg, but it increased by ~19% (17.11 Tg) in a wet year (2012) and decreased by 20% (18.16 Tg) in a dry year (2001). More importantly, the high grazing intensity played a less significant role in directing grassland AGB dynamics (R2 = 0.024,P = 0.599). Future efforts are needed to explore how within‐type variation of vegetation may change temporally and spatially in accurate estimate of AGB across heterogeneous landscapes, as well as the potential underlying mechanisms from biological, physical, and human perspectives.
Universal Basic Income in British Politics, 1918–2018: From a ‘Vagabond's Wage’ to a Global Debate
Authors: SLOMAN PETER
Published: December 2017

The idea of a Universal Basic Income (UBI) has moved rapidly up the British political agenda in recent years, with support from the Green Party, the Royal Society of Arts, and left-wing writers such as Paul Mason. Shadow Chancellor John McDonnell has set up a working group to examine its implications, and four Scottish councils are hoping to launch pilot schemes. Contemporary British interest in UBI forms part of a lively global debate about automation, inequality and precarious labour, but it also draws on a long history of proposals for tax-benefit reform within UK social policy. This article identifies five waves of enthusiasm for basic income in Britain over the past century and highlights patterns of continuity and change. It shows that interest in the proposal has been greatest at times of pessimism about the future of the labour market, though concerns about the ethics and affordability of unconditional payments have always been difficult to shake. Advocates of UBI have also struggled to reconcile the technocratic approach of its Conservative and Liberal supporters with the transformative ambitions of the radical left. It remains to be seen whether the recent growth of left-wing support for UBI will improve its prospects of implementation.
Assessing the impact of public education on a preventable zoonotic disease: rabies
Authors: HASANOV E. , ZEYNALOVA S. , GELEISHVILI M. , MAES E. , TONGREN E. , MARSHALL E. , BANYARD A. , MCELHINNEY L. M. , WHATMORE A. M. , FOOKS A. R. , HORTON D. L.
Published: December 2017

Effective methods to increase awareness of preventable infectious diseases are key components of successful control programmes. Rabies is an example of a disease with significant impact, where public awareness is variable. A recent awareness campaign in a rabies endemic region of Azerbaijan provided a unique opportunity to assess the efficacy of such campaigns. A cluster cross-sectional survey concerning rabies was undertaken following the awareness campaign in 600 households in 38 randomly selected towns, in districts covered by the campaign and matched control regions. This survey demonstrated that the relatively simple awareness campaign was effective at improving knowledge of rabies symptoms and vaccination schedules. Crucially, those in the awareness campaign group were also 1·4 times more likely to report that they had vaccinated their pets, an essential component of human rabies prevention. In addition, low knowledge of appropriate post-exposure treatment and animal sources of rabies provide information useful for future public awareness campaigns in the region and other similar areas.
Acousmatic Music as a Medium for Information: A case study of Archipel
Authors: Campion Guillaume , Côté Guillaume
Published: December 2017

This article discusses the inclusion of concrete informative elements within acousmatic music, in an attempt to mix acousmatic music and sound documentary into a form of socially engaged sound art. Inspired by existing sound practices that make strong use of the sonic reality, such as soundscape composition or radiophonic art, the authors explain how they aim to address socially relevant topics within pieces where music and information are considered of equal importance. To that end, they give a detailed description of their approach through the analysis of the composition process behind Archipel (Côté and Campion 2016), a 29-minute piece focused on the access to the waterfront in the city of Montréal, Québec. Through an alloy of interviews, sound recordings gathered on the shores of Montréal and typically acousmatic sound-processing and synthesis, the piece attempts to portray the challenges and opportunities encompassed by this topic. Having found the need to go beyond the acousmatic concert format for this kind of work, the authors also briefly discuss how they are currently expanding the project to include an interactive website and a mobile application that will complement the initial concert piece.
Relapses in three patients with Takayasu arteritis under tocilizumab treatment detected by contrast enhanced ultrasound
Authors: Czihal Michael , Lottspeich Christian , Schröttle Angelika , Treitl Karla Maria , Treitl Marcus , Leipe Jan , Schulze-Koops Hendrik , Hoffmann Ulrich , Dechant Claudia
Published: December 2017

Abstract. Takayasu arteritis (TA) is a rare large vessel vasculitis, affecting the aorta and its major branches, typically in young women. In this case report, we present three cases of young women of Caucasian descent who experienced relapses while under treatment with the monoclonal humanized antibody to the interleukin 6 receptor, tocilizumab. Active vasculitic lesions of the supraaortic (common carotid and axillary) arteries were detected and characterized via high resolution contrast enhanced ultrasound. Based on these cases, we discuss the potential role of contrast enhanced ultrasound in the diagnosis and follow-up of TA as well as the current data on the efficacy of tocilizumab in the treatment of TA.
Methodenpapier zur Koordination der Datenerhebung und -auswertung an Hochschul- und Ausbildungsambulanzen für Psychotherapie (KODAP)
Authors: Velten Julia , Margraf Jürgen , Benecke Cord , Berking Matthias , In-Albon Tina , Tania Lincoln  , Lutz Wolfgang , Schlarb Angelika , Schöttke Henning , Willutzki Ulrike , Jürgen Hoyer
Published: December 2017

Zusammenfassung. Die Forschung an psychotherapeutischen Hochschulambulanzen (HSA) leistet einen entscheidenden Beitrag zur Behandlung von Menschen mit psychischen Störungen und zur Weiterentwicklung und wissenschaftlichen Fundierung von Psychotherapie im Kindes-, Jugend- und Erwachsenenalter. Durch das im Jahr 2013 gestartete Projekt zur Koordination der Datenerhebung und -auswertung an Forschungs- und Ausbildungsambulanzen für Psychotherapie (KODAP) sollen unter der Trägerschaft des Verbundes universitärer Ausbildungsgänge für Psychotherapie unith.ev ab 2018 jährlich relevante Daten aus den teilnehmenden HSA aggregiert und gemeinsam ausgewertet werden. Im vorliegenden Beitrag beschreiben wir die mit dem Projekt im Zusammenhang stehenden rechtlichen, methodischen und durchführungstechnischen Herausforderungen sowie den derzeitigen Stand des Kooperationsprojektes, einschließlich einer für das Jahr 2017 geplanten Pilotstudie.
Du magst mich nicht, weil ich hässlich bin!
Authors: Schmidt Jennifer , Martin Alexandra
Published: December 2017

Zusammenfassung. Theoretischer Hintergrund: Viele Personen befürchten Zurückweisungen aufgrund ihres Aussehens. Übermäßige „aussehensbezogene Zurückweisungssensitivität“ (ARS) kann jedoch zur Entstehung und Aufrechterhaltung von – insbesondere körperfokussierter – Psychopathologie beitragen. Fragestellung: ARS ist im deutschsprachigen Raum wenig untersucht, da Erhebungsinstrumente fehlen. Daher war die Validierung einer deutschen „Appearance-based-Rejection-Sensitivity-Scale“ (ARS-D; Park, 2007 ) Ziel der Studie. Methode: Nach Übersetzung des englischen Originals wurde die psychometrische Güte der ARS-D in einer Online-Befragung getestet (n = 391). Ermittelt wurden Itemcharakteristika, Faktorstruktur, Reliabilität und Konstruktvalidität. Ergebnisse: Die ARS-D zeigte bei einfaktorieller Struktur sehr gute Reliabilitätsindizes. Die psychometrischen Eigenschaften ließen sich bei einer auf 12 Items gekürzten Skalenvariante (Original: 15 Items) weiter verbessern. Signifikante Korrelationen mit körperdysmorpher Besorgnis, Essstörungssymptomatik und Depressivität (rs > .30) indizieren Konstruktvalidität. Schlussfolgerungen: Die ARS-D ist zur Erfassung und weiteren Erforschung der Rolle aussehensbezogener Zurückweisungssensitivität bei verschiedenen Störungsbildern geeignet.
Correction: Corrigendum: Feasibility of placenta-derived mesenchymal stem cells as a tool for studying pregnancy-related disorders
Authors: Fuchi Naoki , Miura Kiyonori , Doi Hanako , Li Tao-Sheng , Masuzaki Hideaki
Published: December 2017

Scientific Reports 7: Article number: 46220; published online: 12 April 2017; updated: 22 December 2017. The original version of this Article contained an error in Affiliation 1 which was incorrectly listed as ‘Department of Obstetrics and Gynaecology, Nagasaki University Graduate School of Medicine, Nagasaki, Japan’.
Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome
Authors: Han Jianlin , Soloshonok Vadim A. , Klika Karel D. , Drabowicz Józef , Wzorek Alicja
Published: December 2017

This review covers recent developments for optically active sulfoxide preparations and the problem of accurate determination of the stereochemical outcome due to the self-disproportionation of enantiomers (SDE).
Fabrication and assessment of an electrospun polymeric microfiber-based platform under bulk flow conditions with rapid and efficient antigen capture
Authors: Hoy Carlton F. O. , Kushiro Keiichiro , Takai Madoka
Published: December 2017

A sensitive and rapid membrane capable of antigen capture in 5 seconds compared to a conventional method in 60 minutes.