bluuebunny/crossref_metadata_2025 huggingface dataset:
A prospective observational study to assess serial salivary estriol measurements during third trimester of pregnancy as a marker for predicting spontaneous preterm labor in pregnant women
Authors: Karunakaran Lalithambica , Damodaran K. Geetha , N. Sreedevi , K. M. Rajesh
Published: February 2023

Introduction and Aim: Preterm labor is a matter of concern in developed and developing nations, rural and urban areas as well. In this context a relatively cheaper biochemical marker in a specimen which can be easily collected from pregnant women will be beneficial in rural areas. Hence, in this context salivary estriol was selected for studying its diagnostic potential.
 
Materials and Methods: A prospective study was conducted in two sittings (1st sitting at 26 to 29 weeks and 2nd after 2-4 weeks of gestation) among pregnant women (n= 206) who attended T.D. Medical College for antenatal check-up. The salivary samples were collected and estriol (E3) assayed by ELISA. The pregnant women were followed up till delivery to know the type, as term (n=194) or preterm (n=12). MedCalc was used for statistical analysis.
 
Results: Reference interval of increase in salivary E3 over a period of 2 - 4 weeks in pregnant women during 26 – 32 gestational weeks who delivered at term by nonparametric method was 16 to 1468 pg/ml. Gestational period wise reference intervals of salivary estriol at 26- 28, 29 – 30 and 31 to 32 weeks were 74-3227, 119 -3422 and 203-4346 pg/ml respectively. There was a statistically significant difference in the increase in salivary estriol among different time intervals (p=0.001). Diagnostic cut off values of single measurements of salivary E3 and increase in salivary estriol between 2-4 weeks were 492, 561 and 159 pg/ml without acceptable diagnostic accuracy.
 
Conclusion: Serial rise in salivary estriol at 2-4 weeks interval can be utilized but not a single measurement to monitor fetoplacental wellbeing. The high NPV of serial rise in salivary estriol (E3) suggests its usefulness to exclude chances for preterm labor.
Reliability of inflammatory markers as predictors of infection in open long bone fractures
Authors: Somayaji Haridas , Shetty Ashwin , Pandikasalayil Visakh , Hegde Anoop
Published: February 2023

Introduction and Aim: Open fractures are associated complications such as infections, osteomyelitis, non- union. Levels of CRP, ESR and TLC increases during various types of tissue injury. This study aimed at estimating the effect of deranged peri-operative CRP, ESR, in patients with open long bone fractures and to assess them as significant peri-operative markers of postoperative infection.
 
Methodology: Patients with open long bone fractures during the period Jan 2019 to June 2020 were selected for the study. Serum CRP, ESR and TLC levels were measured preoperatively and on postoperative days 3 and 10. Patients were followed up in the ward for 14 days and after 6 weeks for signs of infection. These pre-operative, post-operative data and incidence of infection were estimated.
 
Results: In the present study 5 out of 32 cases developed infection. In infected cases CRP values were persistently elevated on post-operative day 3 and 10 while in non- infection group it elevated on postoperative day 3 and dropped to lower levels by postoperative day 10. It was statistically significant on preoperative data and on post-operative 10th day data. While the ESR and total WBC count showed no such correlation.
 
Conclusion: Serial CRP measurements can be considered as a more definitive reliable inflammatory marker as compared to ESR and total white blood cell count, in predicting postoperative infections in open long bone fractures.  The elevated serial CRP levels postoperatively and their continued persistence in open fractures is potentially an early screening tool for infection before clinical signs of infection appear.
Immunological inflammatory factors in patients diagnosed with COVID-19
Authors: Abbas Mohammed S. , Ahmed Ahmed Ghaith , Ali Sura Qusay , AL-Rubaii Bahaa Abdullah Lafttah
Published: February 2023

Introduction and Aim: Due to the Coronavirus outbreaks, the SARS-CoV-2, also known as COVID-19, has claimed several lives around the world, with the majority of them being elderly, suffering from underlying chronic illnesses, or living in vulnerable conditions. This study aimed to find the immunological factors CD-79, CD-4, IL-2, and TNF-B in COVID-19 patients utilizing nucleocapsid-(N), a protein structure that interacts with genomic RNA to create complexes.
 
Materials and Methods: SARS-COV-2 infection was detected using RT-PCR. The serum levels of IL-2 and TNF-B, as well as the concentrations of CD4 and CD79, were measured. This study included 100 COVID-19 patients.
 
Results: The results showed that the serum concentration of TNF-beta and IL-2 in COVID19 patients was significantly higher than that in the general population (with acute and moderate illness) when compared to normal control groups (p 0.05). COVID-19 patients reported higher levels of CD79 as well as CD4 expression than healthy control groups in a study of activated markers.
 
Conclusion: Infection with SARS-COV-2 has a high impact on various immunological and inflammatory markers in patients.
Study of the association of toll like-4 receptor gene polymorphism (rs1927911) and susceptibility to urinary tract infection among Iraqi patients
Authors: Allami Risala H. , Abdullah Muhanad Najm , K. Al-Ani Basma , AlChalabi Rawaa , S. Hamzah Sawsan
Published: February 2023

Introduction and Aim: Toll-like receptors (TLRs) are cell innate immune receptors that explore microbial molecules. A quantity of single-nucleotide polymorphisms (SNPs) within the TLR genes have been related with altered susceptibility to infectious, inflammatory, and allergic diseases suggesting: This study was conducted to investigate the relationship between genetic polymorphism in TLR4 gene (rs1927911) with susceptibility to UTIs in a sample of Iraqi patients.
 
Materials and Methods: Blood samples were collected from 220 patients who had UTIs and 69 healthy subjects as control group, during the period from October 2021 to March 2022, at the Rheumatology Department of Clinic Consultant at Al-Yarmouk Hospital. The genetic study included an extraction of genomic DNA and PCR technique, to detect the role of TLR4 gene in the variation site (rs1927911) as a risk factor for the incidence of UTIs.
 
Results: The results of genotype distribution and allele frequency of rs1927911 indicated, CC (18.6 %), CT (70 %) and TT (11.4 %) among the patients while 57.9 % for CC and 26.1%; 16% for CT, TT genotypes respectively of healthy control. Heterozygous (CT) may be considered as a risk factor among UTIs patients. The results revealed significant differences between UTIs patients and healthy controls in serum levels TLR4, IL-6 IL-2, TNF-alpha and IL-10 at P 0.005. In addition, the data found a highly significant difference of serum level of TLR4 protein with patients who have a carrier CT genotype.
 
Conclusion: our findings indicated that the carriers of CT genotype of TLR4 (rs1927911) were significantly more prone to UTIs.
Expression and cytotoxic effect of recombinant Newcastle Disease Virus (rNDV) vector expressing enhanced green fluorescent gene in JHH5 cell line
Authors: Rasoul Lubna Muhi , H. Allami Risala , Alshibib Ammar Luay , Al-Rubaii Bahaa Abdullah laftaah , Hadi Sale Tahreer
Published: February 2023

Introduction and Aim: In medicine, the term ‘cancer’ is used to describe a group of disorders defined by uncontrolled cell growth and the ability to invade and metastasize to other organs. As a result of the body's ability to fight conventional cancer treatments, it is essential to look for alternative therapeutic avenues. Recent years have seen a rise in the application of reverse genetics techniques including the Newcastle disease virus as an oncolytic agent in tumor models of immunocompetent malignancy. In preclinical studies, recombinant NDV (rNDV-GFP) that expresses foreign genes was shown to be more effective in cancer therapy. The goal of this study was to examine the in vitro anticancer effects of GFP-expressing, genetically modified Newcastle disease virus (rClone3-GFP) strains on the JHH5 hepatocellular carcinoma cell line.
 
Materials and Methods: To generate a recombinant NDV, the GFP gene was inserted into the genome of an NDV strain (NDVClone30) by reverse genetics technology, where it now resides in the region of the genome occupied by the F and HN genes (rNDV-GFP). Using the MTT assay, we evaluated rNDV-GFP for its oncolytic potential against JHH5 cancer cells. Cytopathic effects were analyzed using fluorescent and light microscopy.
 
Results: We observed that 96 hours post infection, the recombinant virus was capable of inducing tumor cell death in a time-dependent way.
 
Conclusion: Recombinant NDV strains expressing GFP, demonstrated good results in inhibiting tumor growth. Our results pave the door for the application of recombinant NDV as a viral vector for the treatment of liver cancer.
Effect of integrated approach of yoga therapyonloneliness in elderly: An interventional study
Authors: Panigrahi Manorama , Shree Prativa , Prasad Swain Dinesh
Published: February 2023

Introduction and Aim: A person must be adaptable and learn new coping mechanisms to deal with the changes that are common to these stages of life to cope with the changes that come with getting older. But various research also give evidence that loneliness, depressions are very much common during old age which is a significant contributor to suicide and suicide attempts. Incorporating Integrated Approach of Yoga Therapy, one can able to reestablish the link betweenhis mind, body with the present moment, alleviates loneliness, and boosts self-esteem. The objective of the study to know the effect of integrated approach of yoga therapy on loneliness of elderly people.

 

Materials and Methods: The study was carried out by the researcher taking 50 older people between the age group of 60 to 80 following the inclusion and exclusion criteria and through purposive sampling method. The study was done by using one sample group for pre and post-test assessment. All the participants had undergone a practice session of 12weeks in the nearby Temple premises. They were instructed to lead regular lives while taking their medications as prescribed and to maintain a healthy eating pattern. The UCLA questionnaire was used to evaluate loneliness before and after practice.

 

Results: After regular three months practice, the UCLA scale showed significantly decreasing trend. The sample average of the pre- and post-test data showed significant differences enough to be statistically relevant.

 

Conclusion: Adopting IAYT into their regular lifestyle, seniors can reduce their loneliness and enhance self- esteem.
Extracellular E-selectin levels and its association with insulin resistance: Putative role of E-selectin as a biomarker of oxidative stress linked vascular manifestations in diabetic nephropathy
Authors: Farid Babu Meka , A. R. Srinivasan , G. V. Benerji , M. S. Ravikumar
Published: February 2023

Introduction and aim: E-selectin, a cell adhesion molecule depicting nexus with oxidative stress in hyperglycemia has been documented in several other clinical conditions.  The present study centers around the putative role of E-selectin as a biomarker of diabetic nephropathy linked to oxidative stress.

 

Materials and Methods: 150 type 2 diabetics in the age group of 35 - 50 years were classified into three groups, comprising 50 each, based on albuminuria. Fifty healthy age and gender matched individuals constituted the control. Extracellular E-selectin and Insulin were quantitated appropriately. Measurement of HbA1c and microalbumin were also enabled.  Routine biochemistry analyses were undertaken, based on established automated procedures. The study was initiated only following approval accorded by the Institutional Ethics Committee.

 

Results: E-selectin levels in serum were significantly associated with Urine Albumin-to-Creatinine Ratio (UACR) and Insulin resistance in the light of estimated Glomerular Filtration Rate.

 

Conclusion: E-selectin levels could thus act as a putative biomarker of diabetic nephropathy linked to oxidative stress, as observed in insulin resistant type 2 diabetes.
Glycosaminoglycans from fish waste alleviate high fat diet induced obesity via modulating plasma biomarkers and fatty acid profile of obese C57BL/6 mice
Authors: V. Geetha , Kumar G. Suresh
Published: February 2023

Introduction and Aim: Glycosaminoglycans are sulphated polysaccharides which shows various biological activities including anti-obesity, anti-inflammation etc., Extracted glycosaminoglycans (e-GAGs) from mackerel fish waste was studied for their potential as an anti-obesity molecule by in-vivo mechanisms. An attempt was made to study their beneficial effects in regulating plasma biomarkers and fatty acids of liver and fecal matter.

 

Materials and Methods: In-vivo studies were conducted on male C57BL/6 mice (20-22g, 6-8 weeks of age). The animal studies had the IAEC (150/2019) clearance from CSIR-CFTRI, Mysuru. Animals were fed with a high fat diet and the e-GAGs treatment was at 0.4 and 0.8% through diet. Plasma analysis was done with commercially available kits; fatty acids were analyzed by gas chromatography as fatty acid methyl esters. Histopathology was carried out with H&E staining.

 

Results: Plasma biomarkers like SGOT, SGPT, ALP, creatinine and LDH were reduced in the treatment groups in dose dependent manner compared to high fat fed groups. SFA in the liver was highest in the high fat fed group (54.25%), ameliorated to 50.25 and 48.35% with the e-GAGs fed at 0.4 and 0.8% through diet respectively. Fecal fatty acid composition showed the higher (p<0.05) elimination of SFA in the treatment groups. Tissue histopathology of spleen, kidney and pancreas showed the highest damage in the high fat fed group and normalized with the e-GAGs treatment.

 

Conclusion: e-GAGs from fish waste could be beneficial in modulating obesity via modulating fatty acid composition and tissue protection from the obesity induced damage and benefit as a potent anti-obesity molecule.
Augmentation of in vitro cytotoxic potentiality of crude methanolic leaf extract of Olea dioica as a pivotal anticancer source
Authors: Krishnappa Srinivasa , Karthik Yalpi , Shantaram Manjula
Published: February 2023

Introduction and Aim: Tumor is the major cause of death world-wide, with an approximate 10 million fatalities in 2020, or almost one in every six deaths. The concerns with the current commercially available anticancer medications' low selectivity and persistent side effects have driven the research of safer and more effective chemotherapeutic drugs. The current work is focused on determining the cytotoxic potential of crude methanolic extract of Olea dioica leaves against various cancer cell lines viz., A549 (human lung cancer), HCT116 (human colorectal cancer), HeLa (human cervical cancer), MCF-7, and MDA-MB-231 (human breast cancer).

 

Materials and Methods: The cells were treated with crude methanolic extract at five different concentrations viz., 25, 50, 100, 250 and 500 µg/ml to assess the cell viability.

 

Results: The results from the assay performed for five cell lines have shown that methanolic extract of O. dioica has an exponential cytotoxicity potential on HeLa cell line followed by MCF-7 (IC50 value 81.05), HCT116 (106.86) and MDA-MB-231 with IC50 value 81.05, 106.86, 141.34 and 499.24 µg/ml respectively, whereas the A549-human lung cancer cell has shown no cytotoxic activity.

 

Conclusion: The methanol extract of the O. dioica leaf could be recognized as a pivotal source of anticancer compounds, but furthermore research is needed to investigate the chemical components of O. dioica extracts that are mainly accountable for anticancer action and to expound more precise molecular processes of cell death.
High-performance liquid chromatography method development and validation for the quantification of mangiferin in Coffea arabica leaves
Authors: L.S. Hallur Raghavendra , K. Shaikh Faiyaz , V. N. Magare , Kekuda T. R. Prashith , D. M. Chethan , H. S. Anil Kumar , Shantaram Manjula
Published: February 2023

Introduction and Aim: Mangiferin is accompanied by the therapeutic potential for various human ailments. The present study is aimed to develop a validated HPLC method for the quantification of mangiferin in coffee (Coffea arabica) leaves.

 

Materials and Methods: The ­­high-performance liquid chromatography (HPLC) was carried out on Agilent Technologies 1260 LC Infinity Series liquid chromatography system (Agilent, USA) using an isocratic mobile phase of a mixture of methanol and 1% orthophosphoric acid v/v (70:30) at a flow rate 1mL min-1 for 14 min with the controlled temperature at 25°C. The mangiferin content was detected by a UV diode array detector at 258 nm.

 

Results: The linearity of the HPLC system was established in the range of 10-100 ppm mL-1 with a regression coefficient (R2) of 0.99670. The accuracy of the method was assessed by a study performed using 3 different levels, with a 99% average recovery. The limit of detection(LOD) and limit of quantification (LOQ) were 1.3 and 3.9 ppm mL-1. Intraday and interday precision analysis showed the relative standard deviation 0.012342 separately. The content of mangiferin in the coffee leaves was 94 mg/gram (w/w).

 

Conclusion: All necessary factors, such as linearity, accuracy, LOD, LOQ, precision, and % relative standard deviation(RSD), were inside the appropriate limits. The HPLC was validated using all necessary variables with a successful estimation of mangiferin.
Knowledge, attitude and perception about surrogacy among urban working women
Authors: Sultana Qudusia , Vaswani Ravi , Vaswani Vina
Published: February 2023

Introduction and Aim: Infertility is a social stigma in India. Infertility affects 10% of the population in India. Surrogacy is an advanced form of assisted reproductive technique (ART) wherein one woman bears a baby for another woman. Surrogacy is an alternative for the infertile parents for whom it is difficult to have a baby due to medical reasons. The aim was to assess the knowledge, attitude, and perception about the ethical issues involved in surrogacy among urban working women.

Methods: A self-administered questionnaire was devised to determine knowledge, attitude, and perception about surrogacy among young working women. Questionnaire was sent for validation and then distributed to urban working women between the age group of 25-35 years. The questionnaire consisted of 21 questions with a range of 4-point response options and 1 open-ended question. Based on their response given a descriptive analysis was done using SPSS 16.

Results: The urban women were aware of the ethical principles. 63% believe women should not be forced and have complete autonomy in making decisions. 60% believed Surrogate mothers and the baby born of surrogacy should not be ill-treated by the community and 70% said they should be given respect like any other human being.

Conclusion: Altruistic surrogacy should be promoted and not commercial surrogacy as commercial surrogacy leads to the exploitation of the mother’s womb for money. 70% of women in our study believe that the Indian government should not promote surrogacy and in order to protect the rights and prevent injustice suitable Laws should be made and put into action.
Graded repetitive arm supplementary programme (GRASP) and virtual reality to improve upper limb function in patients with acute stroke - An experimental study
Authors: S. Dhanusia , V. Rajalaxmi , N. Suriya , Kumar Bharath
Published: February 2023

Introduction and Aim: The objective of the study is to improve upper limb function in patients with acute stroke using graded repetitive arm supplementary program (GRASP) and virtual reality. Stroke is described as an sudden neurological outburst brought on by impeded blood flow via the brain’s blood vessels. Stroke has an annual mortality rate of 5.5 million which is the 2nd leading cause of mortality.

Materials and Methods: Fourteen patients were randomly split into two groups, Group A and Group B in A.C.S Medical College and Hospital. Inclusion criteria were persons with first ever acute stroke confirmed by CT or MRI, modified Ashworth scale less than 2, Fugl- Meyer score between 10 to 57, age > 18, both genders, eager participants who are willing volunteers for the study. Exclusion criteria were who were mentally unstable, other neurological conditions, any orthopaedic conditions, modified Ashworth scale more than 2, Fugl Meyer score less than 10 or more than 57, age group < 18, patients with TIA were excluded. Group A trained with GRASP program. Group B trained with virtual reality. Both groups consist of 7 patients and training given for 8 weeks, 60 minutes per day for 6 days a week.

Results: This study demonstrates a statistically significant difference between group A and group B in the hand-held dynamometer, Fugl-Meyer evaluation upper extremity, action research arm test, and EMG with a p value of 0.001. However, when compared to group B, group A exhibits greater relevance across the board.

Conclusion: The study concludes that graded repetitive arm supplementary programme in acute stroke patients demonstrates good recovery in upper limb function.
A rare case of central post-stroke pain in a patient with migraine and lacunar infarcts in the medulla oblongata
Authors: Mamytova Elmira , Mamytov Mitalip , Karbozova Kunduz , Jusupova Asel , Kadyrova Begimai , Toychueva Aiperi , Atabekova Alina , Vityala Yethindra , Tagaev Tugolbai
Published: February 2023

Studies about headaches associated with acute ischemic stroke in patients suffering from migraine were limited, and therefore we present a clinical case of central post-stroke pain (CPSP) in a 47-year-old woman with migraine and lacunar infarcts in the medulla oblongata and also possible mechanisms of CPSP in patients with migraine. Magnetic resonance imaging of the brain revealed lacunar infarction in the medulla oblongata on the right (vertebral artery basin) and a single focus of gliosis in the parietal lobe on the right. Magnetic resonance angiography of cerebral vessels showed the fetal type of structure of both posterior cerebral arteries. This clinical case is a complex clinical situation of a combination of secondary headaches (post-stroke) in a patient with a primary headache (migraine), which was successfully treated by the combined administration of first-line drugs for the treatment of neuropathic pain in a patient with lacunar infarcts in the medulla oblongata. The treatment of CPSP is a difficult task due to the insufficiently unexplored mechanisms of development, the most effective approaches are those aimed at reducing the increased excitability of neurons.
The Effect of Sexual Ethics Education on Adolescents at SMP Negeri 1 Pematang Bandar
Authors: Sirait Esti Marlina , Sitorus Esther
Published: February 2023

This study aimed to determine the effect of sexual ethics education on adolescents at Pematang Bandar Middle School for the 2020/2021 academic year. The sample in this study was all 40 grade VIII students of SMP Negeri 1 Pematang Bandar. The technique used to analyze research data is quantitative data analysis. The data obtained in quantitative form is converted into qualitative data concerning the Likert scale. Data were analyzed using descriptive and inferential statistical techniques. From the study results, it can be concluded that there is a significant influence on sexual ethics education on the treatment of adolescents at SMP Negeri 1 Pematang Bandar for the 2020/2021 academic year. The conclusions from the research were given to every teacher there to pay more attention to every act of behavior shown by each student in their development into adulthood.
WORKPLACE TOXICITY AND EMPLOYEE PERFORMANCE OF MANUFACTURING FIRMS: EVIDENCE FROM NIGERIA
Authors: Damaro Olusoji ARUBAYI
Published: February 2023

Previous studies on work place toxicity has mostly focused on employee satisfaction as well as organizational performance. However, the relationship between Workplace toxicity variables and employee performance has not been established. Consequently, this study assesses the relationship between the variables of workplace toxicity such as narcissistic behaviour, harassment, offensive/aggressive leadership, bullying as well as ostracism and employee performance. This study bridged such gap that may be summarized as follows: there is relationship between narcissistic behaviour, harassment, offensive/aggressive leadership, ostracism, bullying and employee performance. Participants were drawn from selected water production factories operating in the Niger-Delta Region of Nigeria. A structured questionnaire was administered to one hundred and thirty-two respondents. The Pearson Product Moment Correlation results indicate that that there is a relationship between all the variables of Workplace toxicity and Employee Performance. The study recommends, there should be zero harassment policies implemented in the workplace and bullying in the workplace should not be tolerated and victims should be encouraged to speak up via a safe medium.

Keywords:  Workplace, Toxicity, Narcissism, Harassment, Offensive/Aggressive, Ostracism,

         Bullying, Employee Performance.
WORK-LIFE BALANCE PRACTICES AND EMPLOYEES’ PERFORMANCE: A CORRELATIONAL SURVEY OF COMMERCIAL BANKS IN DELTA AND BAYELSA STATES, NIGERIA
Authors: Odita Anthony Ogomegbunam
Published: February 2023

This study investigated work-life balance and employees’ performance in some selected commercial banks in Delta and Bayelsa States, Nigeria. The correlational type of survey research design was adopted and the study’s population comprised all the employees of commercial banks with presence in Delta and Bayelsa States out of which seven were selected. 323 employees from the seven selected banks with branches in Abraka, Delta State and Yenizwe Gene, Bayelsa State formed the study’s sample. This research was successfully carried out and completed with the aid of a self-structured questionnaire. 323 copies were personally administered by the researcher to the target respondents and 229 copies were properly filled, scored, and found usable for analysis. The simple percentage, frequencies, charts, mean and standard deviation were used in presenting the respondents’ data on the research items while the Pearson Correlation was adopted for testing the formulated hypotheses. It was discovered that the work leave initiatives practiced among the banks concerns maternity, marriage; annual type, and sick leave. It was also found out that the extent to which the employees give and receive informal support at the workplace is high but the extent to which flexible work arrangements are adopted and wellness programs are organized was low. However, the results of the tested hypotheses indicated that no significant correlation exists between work leave initiatives, informal support practice, and employee performance while a statistically significant relationship was found between flexible work arrangements, wellness programs and employee performance. The researcher drew conclusions from these findings and recommended that adequate wellness schemes such as health insurance (HIS) should be set up by the management of commercial banks for every worker and little deductions be taken monthly from their remunerations in order to ensure that employees’ health are constantly monitored and checkmated by them.

Keywords: Work-Life, Balance Practices, Delta and Bayelsa States, Health Insurance,

                        Employees’ Performance.
Turats fi Tafsir al Qur'an: Meaning, Development History and Manhaj of the Ulama
Authors: Pardi Habib Husnial
Published: February 2023

Various methods and results of interpretation have emerged (according to the times and needs) that can be accessed by the public in understanding the meaning and content of the Qur'an itself. From the aspect of the text, the Qur'an has not changed since it was first revealed until now, but what has changed is the interpretation of the text in accordance with human space and time. Al-Qur'an is always open to analysis, and interpretation with various tools, methods and approaches. Various variants of the Ulama's manhaj regarding interpretation have emerged as a way to explore the meaning of the content contained in the Qur'an itself. on the other hand, the problem of interpretation arises in line with the complexity of human problems. Therefore, this article will focus on the meaning of interpretation, the history of the development of interpretation which is focused on the classical and medieval eras of interpretation and the variants of the manhaj of the scholars. This paper was prepared based on a review of literature or documents using a qualitative approach, type of content analysis method, Klaus Krippendorf (2004). The primary source used is the literature by "Husayn 'Alawl Mehr" An Introduction to the History of Tafsir and Commentators of the Qur'an (2012), and several other references. Secondary sources are taken from several articles related to the themes studied.
ANALISA METODOLOGI KRITIK HADIS JALALUDDIN AS-SUYUTHI DALAM AL-LA’AALI AL-MASHNU’AH FI AL-AHADITS AL-MAUDHU’AJ
Authors: Muzakki Muhammad Asgar
Published: February 2023

Penelitian ini membahas tentang kriteria hadis maudhu’ menurut Jalaluddin as-Suyuthi dalam kitabnya al-La’aali al-Mashnu’ah fi al-Ahadits al-Maudhu’ah. Diutarakan oleh as-Suyuthi bahwa motivasi utamanya dalam menyusun kitab tersebut adalah, selain membangun kritiknya terhadap hadis-hadis palsu yang tersebar di kalangan umat Islam, juga meluruskan sebagian ‘tuduhan’ palsu terhadap beberapa hadis yang ia anggap keliru. Dengan demikian, dapat dikaji dari kitab al-La’aali; 1) kriteria hadis maudhu’ menurut as-Suyuthi dan 2) karakteristik as-Suyuthi sebagai seorang kritikus hadis. Jenis penelitian yang digunakan merupakan studi literature (library research) atau penelitian pustaka, yang semua datanya bersumber dari bahan-bahan tertulis yang berkaitan langsung maupun tidak langsung dengan topik yang dibahas. Metode yang digunakan dalam penelitian ini adalah metode kritik hadis, baik kritik sanad (an-Naqd al-Khariji) maupun kritik matan (an-Naqd ad-Dakhili). Adapun hadis-hadis yang menjadi sampel penelitian, dirujuk ke kitab aslinya dengan metode Takhrij al-Hadits. Hasil penelitian menunjukkan bahwa kriteria as-Suyuthi dalam menetapkan kepalsuan hadis dalam kitab al-La’aali dari segi sanad adalah; 1) perawi yang mengaku berdusta; 2) perawi yang mengaku secara implisit; 3) perawi yang dikenal sebagai pendusta; 4) perawi majhul; dan 5) perawi yang fanatik terhadap golongannya. Dan dari segi matan; 1) redaksi yang buruk; 2) memiliki makna yang rusak, tercakup di dalamnya bertentangan dengan al-Qur’an, as-Sunnah, realita dan akal sehat; 3) melebih-lebihkan pahala dan dosa terhadap amalan yang sepele; dan 4) tidak terdapat dalam kitab atau hafalan periwayat tsiqah. Penulis juga menyimpulkan bahwa as-Suyuthi termasuk ke dalam kategori mutasahil sebagai seorang kritikus hadis.
HADITS KEUTAMAAN SURAT YASIIN DALAM TAFSIR AL-QURTHUBI
Authors: Munawwar Muhammad Awfa
Published: February 2023

Surat yasiin diantara surat populer dikalangan umat islam, ia sering dibaca di dalam berbagai kegiatan keagamaan, hal ini dikarenakan banyak riwayat yang menjelaskan keutamaan surat tersebut. Imam al-Qurthubi salah satu dari sekian banyak ulama yang menukilkan hal ini dalam karya mereka, ditemukan 9 hadits di dalam tafsir al-Qurthubi yang menjelaskan tentang keutamaan itu. Tafsir ini bercorak tafsir bilma’stur dengan menuliskan banyak riwayat dalam penafsiran. Untuk menghindari pengulangan pembahasan, penulis mencukupkan penilitian terhadap 3 hadits. Setelah dilakukan takhrij, ditemukan ketiga sanad hadits tersebut dhaif, namun kedhaifannya tidak sampai pada level maudhu’. Sedangkan sebagian besar matan hadits ini shahih dan boleh diamalkan karena berada dalam fadhail ‘amal.
ANALISIS BERKURANGNYA IMAN DENGAN DOSA DAN MAKSIAT
Authors: Syarifah Bidayatus
Published: February 2023

Tujuan dari tulisan ini adalah untuk mengetahui tentang hadits-hadits tentang iman dan perbuatan maksiat orang yang beriman. Metode yang digunakan dalam penelitian ini merupakan Analisis Isi, dengan tekhnik pengumpulan data menggunakan cara studi kepustakaan. Selama ini, banyak orang berasumsi bahwasannya iman itu terletak pada ranah teologi saja. Padahal disisi lain ranah individual dan sosiologi memiliki peranan penting sebagai wujud implementasi dari keimanan. Jika dikaji lebih dalam tentang al Qur’an dan Hadis, banyak sekali ayat-ayat maupun teks yang menyatakan bahwa iman itu erat kaitannya dengan amal dan akhlaq. Iman dapat bertambah, dan segala sesuatu yang bisa bertambah, tentu bisa juga berkurang. Bertambahnya keimanan seseorang terjadi ketika orang tersebut melakukan perbuatan-perbuatan shalih. Berkurangnya iman disebabkan adanya kemaksiatan yang dikerjakan dan ditinggalkannya amal shalih. Seorang mukmin berkurang imannya sejauh mana ia meninggalkan amal shalih atau ia melakukan kemaksiatan.
KONTRIBUSI SAHABAT PEREMPUAN DALAM PERIWAYATAN HADIS
Authors: Adawiyah I’adatul
Published: February 2023

Penelitian ini mengkaji subyektifitas perempuan dan kontribusinya di dunia periwayatan hadis terutama ummul mukminin Zainab bint Jahsy dalam Sunan al-arba’ah, Berkaitan dengan hadis yang diriwayatkan oleh Zainab dalam kitab Sunan al-Arba’ah, ada 7 hadis yang berbeda tema. 1 dalam kitab Sunan abi Daud, 2 dalam kitab Sunan al-Tirmidzi, 2 dalam kitab Sunan al-Nasa’i, dan 2 dalam kitab Sunan Ibn Majah. Dan dari ketujuh hadis tersebut dapat diklasifikasikan menjadi 3 tema. Pertama: iddah, kedua: thaharah yang mencakup wudhu dan istihadhah, ketiga: datangnya Ya’juj dan Ma’juj. Tidak terlalu banyak hadis yang diriwayatkan olehnya karena dua faktor. Pertama, ia merupakan Istri yang pertama kali wafat setelah wafatnya Rasulullah yaitu dengan jarak kira-kira 9 tahun. Kedua, masih banyaknya rujukan terhadap hadis nabi selain Zainab yaitu para sahabat utama dan istri-istri nabi lainnya. Dalam penelitian ini digunakan pendekatan kepustakaan (library research) dan bersifat deskriptif analitis. Sumber data primer dalam penelitian ini adalah buku al-Muhadditsat; The Women Scholars in Islam, Biografi 35 Shahabiyah Nabi, kitab Sunan al-Arba’ah yaitu Sunan Abu Daud, Sunan al-Tirmidzi, Sunan al-Nasa’i dan Sunan Ibn Majah, kitab-kitab tarajum untuk menelusuri biografi perawi. Adapun sumber sekunder adalah literatur-literatur lainnya yang berupa kitab, buku, jurnal, majalah atau bentuk kepustakaan lainnya yang memuat tentang, hadis dan ilmu hadis, sejarah dan biografi.
DOA PERNIKAHAN NABI SAW UNTUK FATIMAH DAN ALI
Authors: Zulfarizal Zulfarizal
Published: February 2023

Artikel ini berusaha melacak asal-usul terjemahan doa Nabi Muhammad yang diklaim pernah dibacakan pada pernikahan Ali dan Fatimah. Doa ini populer di kalangan pelaku industri kartu undangan pernikahan. Klaim doa itu terhubung dengan Nabi, Ali dan Fatimah mendorong sebagian pihak berpikir bahwa doa tersebut berasal dengan kaum Syiah. Dengan melakukan penelusuran dan komparasi literatur hadis Sunni dan Syiah, sejauh yang dapat diakses, ditemukan bahwa terjemahan doa pernikahan populer itu memiliki unsur kesamaan dengan redaksi yang dimuat dalam kedua literatur Sunni maupun Syiah. Namun, ada pula detail yang berbeda antara doa yang populer di masyarakat dengan doa yang termuat dalam literatur. Terutama terkait detail manfaat dan bentuk berkah keturunan. Detail tersebut merupakan tambahan di luar hadis. Doa tersebut sejatinya boleh saja diamalkan. Tetapi, penisbatan pada Nabi SAW akan bermasalah jika ditinjau dari sudut pandang Ilmu Hadis.
METODE SYARAḤ HADIS DI INDONESIA
Authors: Rizal Abdul
Published: February 2023

Penelitian ini membuktikan metode Syaraḥ hadis yang digunakan KH. Ali Maksum dalam Hujjah Ahl Sunnah wa al-Jama‘ah menggunakan metode global (ijmali), karena penjelasan yang dilakukan Ali Maksum terhadap hadis secara ringkas, dengan gaya bahasa yang mudah dipahami, tidak menyinggung asbab al-wurud hadis, dan beberapa petunjuk hadisnya bersifat parsial. Metode Syaraḥ yang digunakan KH. Ali Maksum juga mengarah kepada metode komparatif (muqarin). Karena ia menjelaskan hadis yang redaksinya sama atau mirip dalam satu persoalan (tematik) dan mengomparasikan pandangan dan komentar ulama hadis. Karena itu, tampak di dalam metode ini keragaman pendapat. Penelitian dalam penelitian ini menggunakan penelitian kualitatif berbasis kepustakaan (library research). Dalam operasional penelitian ini cara yang dilakukan mengkaji sumber primer karya KH. Ali Maksum; Hujjah Ahl Sunnah wa al-Jama‘ah dan sumber sekunder lain dari buku, artikel, jurnal, dan literature lain yang dibutuhkan untuk memecah persoalan yang sudah dirumuskan. Temuan dalam penelitian ini adalah bahwa KH. Ali Maksum berupaya mengakomodir pandangan-pandangan yang selama ini dianggap bertentangan dengan paham ahlus sunah wal jamaah untuk berdiri senada agar diperoleh titik temu. Ini yang menjadi ciri khas dalam pemikiran hadisnya. Ia sangat memahami perbedaan (khilafiyah) terkait persoalan terkait fikih yang masuk ke dalam sub-sub ijtihad (al-masā’il al-far‘iah al-ijtihadiyah), berpotensi mengakibatkan sikap permusuhan, dan bahkan tindakan kekerasan. Sikap dan pemikiran yang dikedepankan KH. Ali Maksum adalah tidak saling menghina dan merendahkan.
INTERPRETASI SUNNAH GHAIR TASHRĪ’IYYAH MENURUT MŪSĀ SHĀHĪN LĀSHĪN
Authors: Ansharullah Hanif Ahmad
Published: February 2023

Penelitian ini, difokuskan kepada Interpretasi Mūsā Shāhīn Lāshīn tentang hadis-hadis yang dipandang ghair tashrī’iyyah di dalam Fatḥ al-Mun’im Sharḥ Ṣaḥīḥ Muslim. Pada penelitian ini menyimpulkan bahwa segala aspek Nabi saw. adalah teladan sepenuhnya, baik persoalan dunia maupun persoalan Agama. Artinya semua yang datang dari Nabi saw. bernilai ḥujjah, dan bersifat tashrī’iyyah yang mengikat, termasuk perbuatan mubah Nabi saw. Berkaitan dengan hadis-hadis yang dipandang ghair tashrī’iyyah, dari sample yang penulis ambil dari kitab Fatḥ al-Mun’in bi Sharḥ Ṣaḥīḥ Muslim yaitu hadis yang berkaitan dengan makan dengan tiga jari, hadis tentang mencukur kumis dan membiarkan jenggot, hadis tentang menyemir rambut, hadis tentang cara tidur Nabi, hadis tentang pakaian Nabi, hadis tentang obat-obatan, hadis penyerbukan kurma, semuanya dipandang tashrī’iyyah. Namun, walau semua dipandang tashrī’iyyah, ia tetap mempertimbangkan pemahaman hadis yang proporsional, kontekstual dan moderat dengan menggunakan pendekatan 1) pendekatan tekstual; 2) pendekatan sabab wurud atau historis; 3) sosiologis; 4) antropologis; 5) pendekatan fiqih dan maqasid.
TUJUAN DAN URGENSI PENELITIAN HADIS
Authors: Zakiyah Ulfah , Ghifari Muhammad
Published: February 2023

Artikel ini menjelakan tentang pentingnya melakukan penelitian hadis yang secara khusus menjelaskan tentang tujuan dan urgensinya. Penelitian hadis merupakan kajian yang mendalam dan kritis terhadap matan dan sanad hadis yang bersifat dinamis dengan menggunakan metode-metode tertentu untuk menentukan validitas hadis sebagai suatu hujjah bagi kebenaran ajaran Islam. Permasalahan pokok dalam penelitian ini adalah bagaimana urgensi penelitian sanad dan matan hadis sebagai unsur penting untuk menentukan kualitas suatu hadis? Untuk menjawap pertanyaan tersebut maka penelitian ini menggunakan jenis penelitian kepustakaan atau yang dikenal dengan istilah library research. Dari hasil penelitian yang dilakukan maka penelitian ini menyimpulkan bahwa da beberapa urgensi hukum yang mendasari pentingnya penelitian hadits, yakni: pertama, terkait dengan posisi hadits sebagai sumber hukum Islam. kedua, terkait dengan historisitas hadits.
PEMAHAMAN SISWA ATAS HADIS SALAT BERJAMAAH DAN PENGARUHNYA TERHADAP MOTIVASI BERIBADAH DAN PERILAKU SOSIAL
Authors: Hidayatullael Fahmi
Published: February 2023

Penelitian ini menjelaskan tentang persepsi siswa MAN 3 Jakarta Pusat atas pengaruh hadis salat berjamaah terhadap motivasi beribadah dan perilaku sosial. Objek kajian ini adalah hadis salat berjamaah lebih utama dua pulu derajat dibandingkan salat sendiri yang diriwayatkan oleh al-Bukhari. Hadis tersebut banyak dijadikan landasan motivasi bagi pelaksanaan salat secara berjamaah. Kaitannya dengan perilaku sosial adalah bahwa salat berjamaah memberikan dampak terhadap perilaku sosial. Penelitian ini menjawab pertanyaan bagaimana persepsi siswa MAN 3 Jakarta terhadap hadis salat berjamaah yang berpengaruh kepada motivasi beribadah dan perilaku sosial? Untuk menjawab pertanyaan tersebut, penulis menggunakan metode penelitian kualitatif dengan metode pencarian data kepustakaan atau dokumentasi (library research), wawancara (interview), dan observasi. Penelitian ini menemukan hasil beberapa poin: Pertama, Hadis tentang keutamaan salat berjamaah mampu memberikan motivasi kepada para siswa untuk melaksanakan ibadah salat berjamaah. Kedua, menurut para siswa, mereka termotivasi melaksanakan salat berjamaah atas dasar mendapatkan pahala, keinginan dan ketaatan, kewajiban, keadaan, bimbingan atau didikan orang tua, kebiasaan, kedisiplinan waktu salat, dan tergeraknya hati untuk melaksanakan salat berjamaah. Ketiga, salat berjamaah yang dilakukan memberikan dampak positif bagi perilaku sosial siswa terhadap orang lain, yakni perilaku empati kepada orang lain, kerjasama, dan toleransi.
KONSEP TAKDIR DALAM PRESPEKTIF HADIS
Authors: Rukmana Jaya , Amalia Putri Rachmah
Published: February 2023

Artikel ini akan membahas lebih jauh mengenai konsep takdir dalam sudut pandang hadits. Dengan melakukan riset pada beberapa sumber, serta berupaya menjelaskan penulisan ini dengan keselarasan hadits yang menjadi bagian dari sumber hukum islam. Dalam upaya ini ditemukan sejumlah hal. Pertama, takdir adalah kadar dan ukuran, yang berarti ukuran batas kemampuan yang diberikan Allah kepada manusia dalam menjalani kehidupan didunia sebagai wujud kasih sayang Allah terhadap HambaNya. Keberadaan takdir juga merupakan konsep hidup dalam rukun iman keenam, yang menjadikan dasar berpegangnya kaum muslimin dan menjadi pondasi dalam kepercayaan agama. Kedua, pengkajian hadits terhadap takdir ada ketika rasulullah SAW berbicara mengenai ketetapan manusia yang sudah ada bahkan selama lima puluh ribu tahun sebelum proses terciptanya manusia. Ketiga, keterkaitan antara hadits dengan konsep takdir juga dilandasi dengan peristiwa yang merujuk tentang kebesaran Allah. Keempat, adapun jenis takdir secara garis besar yakni, Takdir Mubram yang merupakan Ketetapan Mutlak dari Allah dan Takdir Muallaq yang merupakan Ketetapan Allah yang diikut sertakan dengan Ikhtiar Manusia. Kelima, meliputi seluruh pemahaman yang memiliki perbedaan pendapat disetiap sisi, agaknya memerlukan tinjauan ulang
Telaah atas Pemikiran T.M. Hasbi Ash-Shiddieqy
Authors: Aziza Ira Nur
Published: February 2023

Penelitian ini bertujuan untuk mengeksplorasi metode pemahaman hadis T.M. Hasbi Ash-Shiddieqy dan upayanya dalam mengembangkan kajian pemahaman hadis di Indonesia. Penelitian ini mendukung pendapat yang menyatakan bahwa kajian terhadap metode pemahaman hadis di Indonesia telah sampai pada perkembangan yang dinamis. Hal tersebut tercermin dari usaha para pengkaji hadis di Indonesia dalam merekonstruksi metodologi pemahaman hadis agar dapat menyesuaikan dengan kondisi zaman sehingga lebih dapat diterima oleh masyarakat. T.M. Hasbi Ash-Shiddieqy menjadi salah seorang ulama yang mengambil peran dalam bidang ini, yaitu dengan menerapkan metode pemahaman kontekstual dalam menjelaskan hadis-hadis Nabi Saw. Karakteristik yang melekat pada karya-karya hadis T.M. Hasbi Ash-Shiddieqy juga merupakan bukti bahwa perkembangan kajian terhadap metode pemahaman hadis di Indonesia adalah benar adanya.  Pembacaan terhadap karya T.M. Hasbi Ash-Shiddieqy pada bidang hadis menunjukkan bahwa dalam memahami hadis ia menggunakan beberapa metode, yaitu memahami hadis dengan petunjuk al-Qur’an, mentakwil hadis-hadis musykīl, mengkompromikan hadis-hadis yang bertentangan, merujuk pada sejumlah referensi dan menggunakan beberapa pendekatan yang meliputi pendekatan historis, bahasa dan kesehatan. Adapun upaya Hasbi dalam mengembangkan kajian hadis di Indonesia tergambar dari langkahnya untuk menyajikan karya syarah hadis berbahasa lokal disaat hal tersebut masih jarang ditemui pada awal sampai pertengahan abad ke-20 karena ulama-ulama yang hidup sebelum Hasbi menulis kitab syarah hadis dalam bahasa Melayu dan Arab
MENGATASI RASA KURANG PERCAYA DIRI PERSPEKTIF QS. ALI- IMRAN AYAT 139
Authors: Andini Nuriyah Vika , Suharti Nurul
Published: February 2023

Berkat majunya perkembangan zaman dan teknologi, manusia memperoleh banyak akses kemudahan, diantaranya adalah arus informasi yang dapat dengan mudah diakses. Perkembangan zaman seharusnya membawa peradaban manusia menjadi lebih baik, namun justru sebaliknya, kemajuan zaman menjadikan diri terbawa kedalam arus negatif. Hal yang sering dijumpai adalah masalah krisis percaya diri. Allah menciptakan manusia dengan sebaik-baiknya dengan berbagai kelebihan dan kekurangan. Dengan adanya kekurangan dalam diri manusia, tujuannya agar manusia tidak merasa paling sempurna, tidak merasa sombong ataupun angkuh atas apa yang dimiliki, karena hanya Allah SWT yang Maha Sempurna. Dalam penelitian ini, peneliti menggunakan jenis penelitian pustaka (library research). Objek data yang dicari oleh peneliti adalah dengan mencari literatur-literatur yang sesuai dengan permasalahan yang diangkat. Adapun hasil penelitian ini menunjukkan bahwa krisis percaya diri dapat berasal dari internal dan ekstenal. Upaya yang dapat dilakukan untuk mengatasinya adalah 1) mencari pertemanan yang baik. 2) mensyukuri keadaan, 3) bersikap terbuka.
METODOLOGI ZAMAKHSYARI TENTANG PENGGUNAAN ILMU LUGHAH/BAHASA DALAM TAFSIR AL-KASYSYAF
Authors: Nur Dzulhijati Putri Amelia
Published: February 2023

Tulisan ini bertujuan untuk mengetahui metodelogi ilmu lughowi dengan analisis melalui kitab Tafsīr Al-Kassyāf ‘An Ghawāmiḍ Al-Tanzīl Wa ‘Uyūn Al-Aqāwīl Fī Wujūh Al-Ta’wīl karya Abu al-Qasim Az-Zamakhsyari. Metode yang digunakan dalam tulisan ini adalah metode pendekatan kualitatif dengan metode studi literatur (Library research). Berdasarkan pembahasan, metodologi penafsiran lughowi bisa diketahui dengan cara melihat mufassir dalam menafsirkan ayat tertentu. Dalam konteks tafsir al-Kassyaf ini, Az-Zamaksyari memilki metode khusus dalam menafsirkan ayat tertentu diantaranya: mengawalinya dengan menyebutkan nama surat, makkiyah dan madaniyah, menjelaskan makna nama surat, menyebutkan keutamaan surat, memasukkan qira’at, menjelaskan bahasa, nahwu, sharaf dan ilmu-ilmu bahasa Arab lainnya (secara tahlili), dan menafsirkan ayat dengan mengacu pendapat tertentu dan membantah penafsiran yang dianggapnya tidak tepat.