bluuebunny/crossref_metadata_2025 huggingface dataset:
Real-world study of overall survival with palbociclib plus aromatase inhibitor in HR+/HER2− metastatic breast cancer
Authors: Rugo Hope S. , Brufsky Adam , Liu Xianchen , Li Benjamin , McRoy Lynn , Chen Connie , Layman Rachel M. , Cristofanilli Massimo , Torres Mylin A. , Curigliano Giuseppe , Finn Richard S. , DeMichele Angela
Published: October 2022

Data on real-world effectiveness of cyclin-dependent kinase 4/6 inhibitor combination therapy versus endocrine therapy alone are limited. The Flatiron Health Analytic Database was used to assess overall survival (OS) in patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative (HR+/HER2−) metastatic breast cancer (MBC) treated with first-line palbociclib plus an aromatase inhibitor (AI) versus an AI alone in routine US clinical practice. In total, 2888 patients initiated treatment during February 3, 2015–March 31, 2020, with a potential ≥6-month follow-up (cutoff date, September 30, 2020). After stabilized inverse probability treatment weighting, median OS (95% CI) is significantly longer among palbociclib versus AI recipients (49.1 [45.2–57.7] versus 43.2 [37.6–48.0] months; hazard ratio, 0.76 [95% CI, 0.65–0.87]; P < 0.0001). Progression-free survival (95% CI) is 19.3 (17.5–20.7) versus 13.9 (12.5–15.2) months, respectively (hazard ratio, 0.70 [95% CI, 0.62–0.78]; P < 0.0001). These data support first-line palbociclib plus an AI treatment for HR+/HER2− MBC.

(Trial number NCT05361655).
The Ecology-Culture Dataset: A new resource for investigating cultural variation
Authors: Wormley Alexandra S. , Kwon Jung Yul , Barlev Michael , Varnum Michael E. W.
Published: October 2022

Scholars interested in cultural diversity have long suggested that similarities and differences across human populations might be understood, at least in part, as stemming from differences in the social and physical ecologies individuals inhabit. Here, we describe the EcoCultural Dataset (ECD), the most comprehensive compilation to date of country-level ecological and cultural variables around the globe. ECD covers 220 countries, 9 ecological variables operationalized by 11 statistical metrics (including measures of variability and predictability), and 72 cultural variables (including values, personality traits, fundamental social motives, subjective well-being, tightness-looseness, indices of corruption, social capital, and gender inequality). This rich dataset can be used to identify novel relationships between ecological and cultural variables, to assess the overall relationship between ecology and culture, to explore the consequences of interactions between different ecological variables, and to construct new indices of cultural distance.
Crust-mantle decoupling beneath Afar revealed by Rayleigh-wave tomography
Authors: Kumar Utpal , Legendre Cédric P.
Published: October 2022

The Afar triple junction accustoms the diverging plate dynamics between the Arabian, Nubian, and Somalian plates along the Red Sea, Gulf of Aden, and East African rifts. The average anisotropy obtained from shear-wave splitting measurements agrees with the surface motion recovered by geodetic analyses. However, the vertical layering of anisotropy in this region is yet to be accurately determined. Here, we use earthquake seismic data to map Rayleigh-wave azimuthal anisotropy in the crust and lithospheric mantle beneath the East African Rift System. Our results suggest that a layering of anisotropy is present around the East African Rift System. At shorter periods that sample the crust, rift-parallel anisotropy is present in the vicinity of the rift, but in the central part of the rift, rift-normal anisotropy is found. At longer periods, sampling the lithospheric mantle, the anisotropic pattern is quite different. These observations suggest that the crust and lithospheric mantle are mechanically decoupled beneath the environs of the East African Rift System. Similarly, these results suggest complex dynamics within the crust and lithosphere in the region of the Afar triple junction.
The spatial stress of urban land expansion on the water environment of the Yangtze River Delta in China
Authors: Chen Yufan , Xu Yong , Zhou Kan
Published: October 2022

In highly urbanized and industrialized areas, the demand for construction land is expanding, which should have an impact on the water environment. Taking the Yangtze River Delta (YRD) and considering chemical oxygen demand (COD) and ammonia nitrogen (NH3-N) as characteristic pollutants, this study investigated the spatial–temporal characteristics of water pollutant emissions at the county level, optimized the spatial lag model (SLM) to estimate the spatial interaction of urban expansion and water pollutant emissions through direct and indirect effects. The results show that from 2011 to 2015, water pollutant emissions in the YRD decreased significantly and that the high-emissions pattern changed from a contiguous to a scattered distribution. The emissions of COD and NH3-N in counties at various distances from the Yangtze River and coastline show a logarithmic curve relationship. The association between urban expansion and water pollutant emissions was significant and stable. In 2015, every 1% increase in the scale of urban expansion resulted in 0.299% and 0.340% increases in local COD and NH3-N emissions, respectively, and emissions in the adjacent counties synchronously increased by 0.068% and 0.084%, respectively. The results show that to break the association and spatial interaction between urban expansion and water pollutant emissions and alleviate the environmental stress on the YRD, in addition to delimiting an urban expansion boundary and strictly restraining the scale of expansion, improvement in the regional environmental carrying capacity through urban water pollutant treatment facilities and pipe network construction is urgently needed.
Heteropolyacid coupled with cyanoguanidine decorated magnetic chitosan as an efficient catalyst for the synthesis of pyranochromene derivatives
Authors: Rahimzadeh Golnaz , Tajbakhsh Mahmood , Daraie Mansoureh , Ayati Ali
Published: October 2022

In this study, a novel nanocatalyst was successfully prepared by heteropolyacid immobilization of magnetic chitosan-cyanoguanidine composite and fully characterized by different analysis methods, including FTIR, XRD, TGA, SEM, and EDS. The catalytic activity of fabricated composite was examined in a one-pot three-component reaction, involving the diverse active methylene compounds, various aryl aldehydes, and malononitrile in water. The results revealed the efficient catalytic performance of composite, while all reactions proceeded smoothly and led to the formation of the corresponding pyranochromene derivatives in high to excellent yields.
Person-identifying brainprints are stably embedded in EEG mindprints
Authors: Yang Yao-Yuan , Hwang Angel Hsing-Chi , Wu Chien-Te , Huang Tsung-Ren
Published: October 2022

Electroencephalography (EEG) signals measured under fixed conditions have been exploited as biometric identifiers. However, what contributes to the uniqueness of one's brain signals remains unclear. In the present research, we conducted a multi-task and multi-week EEG study with ten pairs of monozygotic (MZ) twins to examine the nature and components of person-identifiable brain signals. Through machine-learning analyses, we uncovered a person-identifying EEG component that served as "base signals" shared across tasks and weeks. Such task invariance and temporal stability suggest that these person-identifying EEG characteristics are more of structural brainprints than functional mindprints. Moreover, while these base signals were more similar within than between MZ twins, it was still possible to distinguish twin siblings, particularly using EEG signals coming primarily from late rather than early developed areas in the brain. Besides theoretical clarifications, the discovery of the EEG base signals has practical implications for privacy protection and the application of brain-computer interfaces.
In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masks
Authors: Schorderet Weber Sandra , Bulliard Xavier , Bonfante Rosy , Xiang Yang , Biselli Silvia , Steiner Sandro , Constant Samuel , Pugin Raphael , Laurent Alexandra , Majeed Shoaib , Lebrun Stefan , Palmieri Michele , Hogg Andreas , Kuczaj Arkadiusz , Peitsch Manuel C. , Hoeng Julia , Stan Adrian
Published: October 2022

During the coronavirus disease (COVID-19) pandemic, wearing face masks in public spaces became mandatory in most countries. The risk of self-contamination when handling face masks, which was one of the earliest concerns, can be mitigated by adding antiviral coatings to the masks. In the present study, we evaluated the antiviral effectiveness of sodium chloride deposited on a fabric suitable for the manufacturing of reusable cloth masks using techniques adapted to the home environment. We tested eight coating conditions, involving both spraying and dipping methods and three salt dilutions. Influenza A H3N2 virus particles were incubated directly on the salt-coated materials, collected, and added to human 3D airway epithelial cultures. Live virus replication in the epithelia was quantified over time in collected apical washes. Relative to the non-coated material, salt deposits at or above 4.3 mg/cm2 markedly reduced viral replication. However, even for larger quantities of salt, the effectiveness of the coating remained dependent on the crystal size and distribution, which in turn depended on the coating technique. These findings confirm the suitability of salt coating as antiviral protection on cloth masks, but also emphasize that particular attention should be paid to the coating protocol when developing consumer solutions.
Deterioration of liver function and aging disturb sequential systemic therapy for unresectable hepatocellular carcinoma
Authors: Shimose Shigeo , Hiraoka Atsushi , Tanaka Masatoshi , Iwamoto Hideki , Tanaka Takaaki , Noguchi Kazunori , Aino Hajime , Yamaguchi Taizo , Itano Satoshi , Suga Hideya , Niizeki Takashi , Moriyama Etsuko , Shirono Tomotake , Noda Yu , Kamachi Naoki , Okamura Shusuke , Nakano Masahito , Kawaguchi Takumi , Kuromatsu Ryoko , Koga Hironori , Torimura Takuji
Published: October 2022

This study aimed to investigate the clinical characteristics of patients with unresectable hepatocellular carcinoma (HCC), who were eligible for sequential systemic therapy. We evaluated 365 patients with HCC who underwent systemic therapy after 2017. The overall survival (OS) was 13.7 months, 19.2 months, and 35.6 months in the first-line, second-line, and third-line or later therapy groups, respectively. Multivariate analysis revealed that the modified-albumin-bilirubin (m-ALBI) grade, macrovascular invasion, extrahepatic spread, discontinuation due to adverse events (AEs), and sequential therapy were independent factors for OS. At the end of each therapy, the ALBI score was significantly worse among patients with discontinuation due to AEs than among those without. The conversion rate to second-line and third-line therapy among patients with discontinuation due to AEs was significantly lower than that among patients without (30.4% vs. 69.2%, p < 0.001; 6.7% vs. 58.3%; p < 0.001, respectively). In the decision tree analysis, m-ALBI grade 1 or 2a and non-advanced age were selected splitting variables, respectively, for sequential systemic therapy. In conclusion, sequential therapy prolonged the OS of unresectable HCC. Additionally, good hepatic function and non-advanced age were clinically eligible characteristics for sequential systemic therapy.
Association between methyl donor nutrients and metabolic health status in overweight and obese adolescents
Authors: Poursalehi Donya , Lotfi Keyhan , Mirzaei Saeideh , Asadi Ali , Akhlaghi Masoumeh , Saneei Parvane
Published: October 2022

Limited evidence is available regarding the association of methyl donor nutrients and adolescents’ metabolic health. Therefore, we investigated the relation between a combination of methyl donor nutrients and metabolic health status of overweight and obese Iranian adolescents. In this cross-sectional study, 203 overweight/obese adolescents were included, using a multistage cluster random-sampling method. Dietary intakes were assessed by a validated food frequency questionnaire. Methyl donor nutrient score (MDNS) was constructed based on deciles of vitamins B2, B6, B9, B12, methionine, choline and betaine. Glycemic profile, lipid profile, blood pressure and anthropometric indices were collected. Participants were classified as metabolically healthy obese or unhealthy obese (MUO) based on International Diabetes Federation (IDF) and IDF/Homeostasis Model Assessment Insulin Resistance (HOMA-IR) definitions. Mean age of adolescents was 13.98 $$\pm$$
±
1.61 y and 50.2% of them was girls. After controlling all of the confounders, individuals in the top tertile of MDNS, had lower odds of MUO (OR 0.36; 95% CI 0.13–0.95) according to IFD criteria. Considering IDF/HOMA-IR criteria, an inverse marginally significant association was observed between the highest tertile of MDNS and odds of MUO (OR 0.36; 95% CI 0.12–1.02) in the fully-adjusted model. Furthermore, significant inverse association was found between each unit increase in MDNS and odds of MUO based on IDF criteria, but not for IDF/HOMA-IR definition. We found that overweight/obese adolescents with higher dietary intakes of methyl donor nutrients were less likely to be metabolically unhealthy. Further studies are needed to confirm the findings.
Accurate detection of perchlorate in epoxy resins via chlorine-35 quantitative quadrupolar NMR (qQNMR)
Authors: Ruiz-Muelle Ana Belén , Lestón-Cabeo Felipe , Fernández Ignacio
Published: October 2022

We present herein the application of a qQNMR method that uses a quadrupolar nucleus such as chlorine-35 for the quantification of perchlorate in epoxy resins.
A microbial quantity monitoring model based on 3D fluorescence data of the cucumber storeroom gas and its use in providing auxiliary early spoilage warning
Authors: Yuan Yunxia , Liu Xueru , Yin Yong , Yu Huichun , Chen Junliang , Li Mengli
Published: October 2022

A microbial quality prediction model for early warning of cucumber spoilage is proposed based on the fluorescence information of the cucumber storeroom gas.
Multiplexed microfluidic chip for cell co-culture
Authors: Watson Craig , Liu Chao , Ansari Ali , Miranda Helen C. , Somoza Rodrigo A. , Senyo Samuel E.
Published: October 2022

A microfluidic chip designed to co-culture cells and control onset of paracrine signaling between chambers.
Synthesis and reactivity of 1-sulfonylcyclooctatriazoles
Authors: Williams Matthew B. , Wells Ruaraidh J. , Boyer Alistair
Published: October 2022

Sulfonyl azides undergo rapid inverse electron demand SPAAC with strained alkynes to deliver 1-sulfonyl-1,2,3-triazoles. Treatment of these with Rh(ii) carboxylate catalyst promotes denitrogenation and transannular 1,5-H insertion or 1,2-H shift.
Recent advancements in understanding the self-assembly of macroions in solution via molecular modeling
Authors: Liu Zhuonan , Qian Kun , Liu Tianbo , Tsige Mesfin
Published: October 2022

Macroions fill the gap between simple ions and colloids in size but display a completely different self-assembly behavior in solution.
Multiple regulation towards an all-in-one NiCuMo/MoOx heterostructure for improving alkaline hydrogen oxidation
Authors: Cheng Yijia , Chen Yuhao , Cai Zhengyang , Wang Ping , Xu Jingcheng , Yan Ya , Wang Xianying
Published: October 2022

A simple one-step electrodeposition enables multiple regulation of the Ni electrode towards an all-in-one NiCuMo/MoOx heterostructure for improving alkaline hydrogen oxidation.
A series of entangled MOFs constructed from flexible dipyridyl piperazine and rigid dicarboxylate: interpenetration, self-penetration, and polycatenation
Authors: Ju Huiyeong , Kim Seulgi , Jung Jong Hwa , Lee Shim Sung
Published: October 2022

By employing a flexible dipyridyl piperazine and a rigid linear dicarboxylate, four MOFs with different entangled structures involving a 3D inclined polycatenane and a 3D self-penetrated framework incorporating cyclic [3]catenane were isolated.
Possibility of chiral recognition by adsorption on enantiomorphous crystals: the impact of crystal surface polarity
Authors: Gus’kov Vladimir Yu. , Gallyamova Gulshat A. , Sairanova Natalia I. , Sharafutdinova Yulia F. , Khalilov Leonard M. , Mukhametzyanov Timur A. , Zinoviev Ilya M. , Gainullina Yulia Yu.
Published: October 2022

The enantioselectivity provided by hippuric acid and phloroglucinol crystals, obtained under Viedma ripening, was studied by the adsorption of menthol enantiomers from solutions and the adsorption of limonene and α-pinene enantiomers from vapors.
A study combining magic-angle spinning NMR and small-angle X-ray scattering on the interaction in the mixture of poly(benzyl methacrylate) and ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide
Authors: Morita Takeshi , Okada Hitomi , Yamada Taisei , Hidaka Ryo , Ueki Takeshi , Niitsuma Kazuyuki , Kitazawa Yuzo , Watanabe Masayoshi , Nishikawa Keiko , Higashi Kenjirou
Published: October 2022

Despite being an LCST system, the NMR results indicate that the number of ionic liquid ions interacting with the solute polymer increases even at temperatures approaching the separation line.
Thermodynamic and dynamic stability in a new potential Cs2AgAsCl6 perovskite: insight from DFT study
Authors: Saha Tusar , Babu Md. Majibul Haque , Arifuzzaman Md. , Podder Jiban
Published: October 2022

A schematic diagram of the possible energy band level for photocatalytic activity: (a) favorable energy band level, (b) unfavorable VBM, and (c) unfavorable CBM position.
Dynamic switching between bound states in the continuum (BIC) and quasi-BIC based on a Dirac semimetal terahertz metasurface
Authors: Gao Jingxiang , Liu Hang , Zhang Man , Liu Meng , Zhang Huiyun , Zhang Yuping
Published: October 2022

This work presents a Dirac semimetal–metal metasurface for the dynamic switching of terahertz-band BIC to quasi-BIC. The display of clear letters is achieved by arranging the metasurface array and applying different voltages.
Cryogenic IR and UV spectroscopy of isomer-selected cytosine radical cation
Authors: Molina Franco , Dezalay Jordan , Soorkia Satchin , Broquier Michel , Hochlaf Majdi , Pino Gustavo Ariel , Grégoire Gilles
Published: October 2022

The UV photodissociation of cryogenic-cooled isomer-selected cytosine–silver complex leads to the production of cytosine radical cation without isomerization.
Tuning CO2 hydrogenation selectivity on Ni/TiO2 catalysts via sulfur addition
Authors: Le Berre Carole , Falqui Andrea , Casu Alberto , Debela Tekalign T. , Barreau Mathias , Hendon Christopher H. , Serp Philippe
Published: October 2022

Although sulfur has long been identified as a poison for Ni catalysts in CO-methanation, its association with Ni on a reducible support allows the selective formation of CO in CO2 hydrogenation.
Advanced aqueous sodium-ion capacitors based on Ni0.25Mn0.75O nanoparticles encapsulated in electrospinning carbon nanofibers
Authors: Gao Mingyu , Song Xinjian , Tan Jianfeng
Published: October 2022

Manganese oxides are promising cathode material candidates with appropriate positive potential windows for low-cost and safe aqueous sodium-ion capacitors (ASICs).
DNA binding, antitubercular, antibacterial and anticancer studies of newly designed piano-stool ruthenium(ii) complexes
Authors: Navale Govinda , Singh Sain , Agrawal Sonia , Ghosh Chandrachur , Roy Choudhury Angshuman , Roy Partha , Sarkar Dhiman , Ghosh Kaushik
Published: October 2022

The chemotherapeutic potential of ruthenium(ii) complexes as DNA binding, antitubercular, antibacterial, and anticancer agents.
Facile preparation of flexible porous carbon fibers as self-supporting sulfur cathode hosts for high-performance Li–S batteries
Authors: Li Yuyun , Lei Dongyuan , Yang Shixun , Chen Jiqun , Zhao Zirui , Guo Junming , Xiang Mingwu , Liu Xiaofang , Bai Wei
Published: October 2022

A makeup cotton derived self-supporting porous carbon fibers with a specific surface area of 2124.9 m2 g−1 are prepared. The optimized S/C cathode with a sulfur loading of 3.0 mg cm−2 delivers the first discharge capacity of 778 mA h g−1 at 0.2 C.
The geno-toxicological impacts of microplastic (MP) exposure on health: mechanistic pathways and research trends from a Chinese perspective
Authors: Xuan Lihui , Xiao Liang , Huang Ruixue
Published: October 2022

Potential genotoxicity of microplastics (MPs) includes accumulation of reactive oxygen species (ROS), DNA damage, cell death, inflammation or genetic regulation which in turn can have consequences for health, such as the induction of carcinogenesis.
Transport of oxytetracycline through saturated porous media: role of surface chemical heterogeneity
Authors: Jin Yinhan , Liu Mengya , Zhang Qiang , Farooq Usman , Chen Weifeng , Lu Taotao , Qi Zhichong
Published: October 2022

The current state of knowledge on the transport behaviors of oxytetracycline (OTC, a typical tetracycline antibiotic) in porous media with heterogeneous chemical surfaces is inadequate.
Selenium nanomaterials induce flower enlargement and improve the nutritional quality of cherry tomatoes: pot and field experiments
Authors: Cheng Bingxu , Wang Chuanxi , Cao Xuesong , Yue Le , Chen Feiran , Liu Xiaofei , Wang Zhenyu , Xing Baoshan
Published: October 2022

Crop yield and quality must be improved to meet the rapid growth of the population.
A quantitative analysis of drinking water treatments for the removal of dissolved microcystins
Authors: Zhang Yanyan , Whalen Joann K. , Cai Chen , Vo Duy Sung , Munoz Gabriel , Sauvé Sébastien
Published: October 2022

The efficacy of removing dissolved microcystins from contaminated waters was evaluated by considering 46 water treatment methods described in 167 published articles.
A high-capacity 1,2:3,4-dibenzophenazine anode integrated into carbon felt for an aqueous organic flow battery in alkaline media
Authors: Xia Xue , Qin Mengna , Sun Yang , Shi Yanjun , Xu Juan , Shen Yong-Miao , Guo Dengfeng , Chen Zhidong , Cao Jianyu
Published: October 2022

A novel organic anode with high mass loading is prepared by integrating 1,2:3,4-dibenzophenazine into a carbon felt substrate via a DES-assisted preparation approach for a high-capacity and long-life alkaline aqueous organic flow battery.
Targeted H2O activation to manipulate the selective photocatalytic reduction of CO2to CH3OH over carbon nitride-supported cobalt sulfide
Authors: Ma Minzhi , Huang Zeai , Wang Rui , Zhang Ruiyang , Yang Tian , Rao Zhiqiang , Fa Wenjun , Zhang Fengying , Cao Yuehan , Yu Shan , Zhou Ying
Published: October 2022

The H2O activation provides protons without the formation of strong oxidative radicals and can achieve the selective photoreduction of CO2to CH3OH.
Tailoring the thermal conductivity of two-dimensional metal halide perovskites
Authors: Thakur Sandip , Dai Zhenghong , Karna Pravin , Padture Nitin P. , Giri Ashutosh
Published: October 2022

Proper thermal management of solar cells based on metal halide perovskites (MHPs) is key to increasing their efficiency as well as their durability.
The polymerization of carvacrol catalyzed by Mn-porphyrins: obtaining the desired product guided by the choice of solvent, oxidant, and catalyst
Authors: Tessaro Patrícia Salvador , Meireles Alexandre Moreira , Guimarães Adriano Silva , Schmitberger Bernardo , Lage Ana Luísa Almeida , Patrício Patrícia Santiago de Oliveira , Martins Dayse Carvalho da Silva , DeFreitas-Silva Gilson
Published: October 2022

Less polar solvents could modulate the catalytic activity of Mn(iii)-porphyrins in carvacrol's oxidation leading to polymer/oligomer formation instead of thymoquinone formation.
Preparation of resin-based composites containing Ce and cationic polymers with abundant promotional affinity sites for phosphate capture
Authors: Shan Xiangcheng , Yang Liyu , Yang Huarong , Song Guilin , Xiao Zuoyi , Ha Chang-sik , Zhai Shangru , An Qingda
Published: October 2022

A new type of composite, D301-Ce+, for efficient and selective phosphate removal.
Thermally-treated MgO/nanocrystalline cellulose immobilized onto a Santa Barbara-16 mesoporous SiO2 template for the sequestration of antibiotics from polluted water
Authors: Omorogie Martins O. , Ilesanmi Faith O. , Alfred Moses O. , Helmreich Brigitte
Published: October 2022

Clean technologies using functional materials as adsorbents for removing antibiotics from polluted water are of great interest, especially for water scarce sub-African countries.
Host–guest molecular doping guide for emissive organic semiconductor crystals
Authors: Kuimov Anatoly D. , Becker Christina S. , Sonina Alina A. , Kazantsev Maxim S.
Published: October 2022

Host–guest molecular compatibility criteria for the doping of conjugated highly emissive semiconductor crystals were revealed.
Enhanced energy storage properties of KNbO3 modified (Bi0.5Na0.5)TiO3–BaTiO3 based lead-free relaxor ferroelectric ceramics
Authors: Yang Fan , Li Qiang , Hou Dingwei , Jia Yuxin , Wang Weijia , Fan Huiqing
Published: October 2022

KNbO3 doping is used to increase the relaxor degree, reduce the remanent polarization, and improve the energy storage performance.
Strategies for the synthesis ofStemonaalkaloids: an update
Authors: Olivier Wesley J. , Henneveld Jackson S. , Smith Jason A. , Hawkins Bill C. , Bissember Alex C.
Published: October 2022

TheStemonaalkaloids represent a large and structurally-diverse family of natural products. A selection of case studies are presented to showcase the key strategies and progress in the synthesis of these natural products since 2009.
Programmable precise kinetic control over crystal phase, size, and equilibrium in spontaneous metathesis reaction for Cs–Pb–Br nanostructure patterns at room temperature
Authors: Piotrowski Marek , Ge Zhongsheng , Wang Yixi , Bandela Anil Kumar , Thumu Udayabhaskararao
Published: October 2022

Growth kinetics involved in spontaneous random clustering of perovskite precursors to a particular cesium–lead–bromide (Cs–Pb–Br) nanocrystal (NC) is a poorly understood phenomenon and its spectroscopic investigation is highly challenging.
Unravelling faradaic electrochemical efficiencies over Fe/Co spinel metal oxides using surface spectroscopy and microscopy techniques
Authors: Kashyap Varchaswal , Pandikassala Ajmal , Singla Gourav , Khan Tuhin Suvra , Ali Haider M. , Vinod C. P. , Kurungot Sreekumar
Published: October 2022

The catalysts derived from Co/Fe nanoparticles display promising activity toward electrochemical reactions. The electrochemical activity of these nanoparticles could be directly correlated to their surface electronic properties.
Green synthesis of highly stable CsPbBr3 perovskite nanocrystals using natural deep eutectic solvents as solvents and surface ligands
Authors: Lu Heng , Tan Xiaohong , Huang Guobin , Wu Shaoru , Zhou Yanmei , Zhang Junying , Zheng Qiaowen , Chen Tianju , Li Feiming , Cai Zhixiong , Zeng Jingbin , Zhang Maosheng
Published: October 2022

Perovskite nanocrystals (PNCs) have attracted widespread attention as promising materials for the optoelectronic field due to their remarkable photophysical properties and structural tunability.
Organocatalytic enantioselective Mannich reaction of isoxazol-5(4H)-ones to isatin-derived ketimines
Authors: Torán Ricardo , Puchán Dario , Sanz-Marco Amparo , Vila Carlos , Pedro José R. , Blay Gonzalo
Published: October 2022

An efficient organocatalytic asymmetric Mannich reaction between isoxazol-5(4H)-ones and isatin-derived ketimines has been developed.
Dithiocarbazate-copper complex loaded thermosensitive hydrogel for lung cancer therapy via tumor in situ sustained-release
Authors: Deng JunGang , Peng Chang , Hou LiXia , Wu YouRu , Liu Wei , Fang GuiHua , Jiang HaoWen , Qin ShanFu , Yang Feng , Huang GuoJin , Gou Yi
Published: October 2022

The Pluronic F127 thermosensitive hydrogels containing copper complex 3 were constructed, which could delay A549 tumor xenograft growth effectively with lower systemic toxicity.
A flexible route to crisp-like metal–organic framework derivatives by crystalline transformation
Authors: Li Hongfeng , Ji Ning , Ji Xingyue , Liu Shangjie , Shen Yu , Pan Ting , Wu Peng , Hui Junfeng , Zha Baoli , Zhang Weina
Published: October 2022

Crisp-like MOF derivatives were fabricated by using MOF particles as precursors via the crystalline transformation process and sulfidation reactions.
Evaluation of surface passivating solvents for single and mixed halide perovskites
Authors: Özeren Mehmet Derya , Pekker Áron , Kamarás Katalin , Botka Bea
Published: October 2022

Various surface passivating solvents with different functional groups were used to investigate solvent–perovskite interactions. The identification of the underlying mechanisms provides insight for new surface passivation strategies.
Silver sulfide decorated carbonaceous sawdust/ES-PANI composites as salt-resistant solar steam generator
Authors: Sadoun Ahmed K. , Gebreil Ahmed , Eltabey Rania M. , Kospa Doaa A. , Ahmed Awad I. , Ibrahim Amr Awad
Published: October 2022

Solar steam generation (SSG) is a potential approach for resolving the global water and energy crisis while causing the least amount of environmental damage.
A practical flow synthesis of 1,2,3-triazoles
Authors: Drelinkiewicz Dawid , Whitby Richard J.
Published: October 2022

Copper-on-charcoal is an excellent heterogeneous catalyst for the alkyne–azide cycloaddition reaction performed under continuous flow conditions. 2-Ynoic acids undergo decarboxylation/cycloaddition cascade giving triazoles bearing small alkyl chains.
Probing the effects of fructose concentration on the evolution of humins during fructose dehydration
Authors: Hu Yexin , Li Hui , Hu Ping , Li Linzhen , Wu Di , Xue Zhidan , Zhu Liangfang , Hu Changwei
Published: October 2022

A universal understanding on the concentration-aggravated evolution of humins during fructose dehydration has been demonstrated, wherein difructose anhydrides act as the key intermediates for both 5-hydroxymethylfurfural and humin formations.
A light-gated regulation of the reaction site by a cucurbit[7]uril macrocycle
Authors: Rad Nazar , Sashuk Volodymyr
Published: October 2022

On–off competitive inhibition is presented. Photoswitchable pseudorotaxane controls the rate of self-reaction and product selectivity of external reactions.
Electronic structure manipulation via composition tuning for the development of highly conductive and acid-stable oxides
Authors: Byeon Young-Woon , Mailoa Jonathan , Kornbluth Mordechai , Lee Gi-Hyeok , Cai Zijian , Sun Yingzhi , Yang Wanli , Johnston Christina , Christensen Jake , Kim Soo , Cheng Lei , Kim Haegyeom
Published: October 2022

Our combined computations and experiments suggest the Mg-Ti-O chemical spaces for novel ternary oxide compounds that can offer high conductivity and corrosion stability to be used in fuel cell applications.
Low-energy intralayer phonon assisted carrier recombination in Z-scheme van der Waals heterostructures for photocatalysis
Authors: Yan Hejin , Guan Qiye , Chen Hongfei , Cui Xiangyue , Shu Zheng , Liang Dan , Wang Bowen , Cai Yongqing
Published: October 2022

Our simulations suggest Z-scheme vdW heterostructures with a facile intralayer sliding and softening intralayer phonon would be beneficial for prolonging the lifetime of carriers for photocatalysis such as water splitting.
Photocatalytic dehydrogenation of organic hydrogen carrier on Pd-TiO2(110) surfaces
Authors: Kang Jeong Su , Baek Ju Yeol , Hwang Hyuntae , Shin Hyeon Suk , Yoon Chang Won , Shin Hyung-Joon
Published: October 2022

Hydrogen stored in C–H bonds of organic hydrogen carrier can be released by UV irradiation, which is attributed to the hot electrons generated by plasmonic effect.
Synergistic bimetallic CuPd oxide alloy electrocatalyst for ammonia production from the electrochemical nitrate reaction
Authors: Jung Wonsang , Jeong Jaewoo , Chae Younghyun , Lee Woong Hee , Ko Young-Jin , Chae Keun Hwa , Oh Hyung-suk , Lee Ung , Lee Dong Ki , Min Byoung Koun , Shin Hyeyoung , Hwang Yun Jeong , Won Da Hye
Published: October 2022

Bimetallic CuPd oxide alloy electrocatalysts can promote selective ammonia production from the nitrate reduction reaction by accelerating the rate-determining hydrogenation of nitrite, which is a critical intermediate.
Tailoring of an ultralow temperature adaptive cellulose nanofiber-based flexible zinc-air battery with long cycle life
Authors: Xue Yichun , Zhou Hang , Wang Keyu , Zhu Hongxiang , Zhuang Linzhou , Xu Zhi , He Hui
Published: October 2022

A cellulose nanofiber-based flexible zinc-air battery with stable cycle was tailored. This battery exhibited a superior performance and adapted ultralow temperature via inhibiting zinc dendrites and ice crystals formation.
Highly luminescent perovskite quantum dots for light-emitting devices: photopatternable perovskite quantum dot–polymer nanocomposites
Authors: Sung Cheng-Han , Huang Shi-Da , Kumar Gautham , Lin Wen-Chi , Lin Chien-Chung , Kuo Hao-Chung , Chen Fang-Chung
Published: October 2022

Photopatternable perovskite quantum dot–polymer composites with feature sizes as small as 3.86 μm are prepared for light-emitting applications.
Triplet transfer from PbS quantum dots to tetracene ligands: is faster always better?
Authors: Gray Victor , Drake William , Allardice Jesse R. , Zhang Zhilong , Xiao James , Congrave Daniel G. , Royakkers Jeroen , Zeng Weixuan , Dowland Simon , Greenham Neil C. , Bronstein Hugo , Anthony John E. , Rao Akshay
Published: October 2022

We report the triplet energy transfer from PbS QDs to four energetically and structurally similar tetracene ligands, even with similar ligands we find that the triplet energy transfer dynamics can vary significantly.
Tunable phase transition temperature and nonlinear optical properties of organic–inorganic hybrid perovskites enabled by dimensional engineering
Authors: Jia Qiang-Qiang , Ni Hao-Fei , Lun Meng-Meng , Xie Li-Yan , Lu Hai-Feng , Fu Da-Wei , Guo Qiang
Published: October 2022

Improving the phase transition temperature and enriching optoelectronics properties have become the top priorities. Herein, we have successfully synthesized two bilayer (2D/3D) perovskite materials based on a single layer perovskite.
pH-Responsive nanomicelles for breast cancer near-infrared fluorescence imaging and chemo/photothermal therapy
Authors: Xu Jingjing , Yang Xiaojing , Tang Xianjiao , Zhao Mei-Xia
Published: October 2022

Responsive, efficient, and multifunctional anticancer nanoparticles were constructed for near-infrared fluorescence-guided synergistic photothermal therapy and chemotherapy.
L’embryon de poule
Authors: Sola Brigitte , Caillot Mélody
Published: October 2022

Le développement de drogues anti-cancéreuses à visée thérapeutique nécessite leur évaluation. Ces drogues candidates sont généralement testées in vitro, sur des lignées cellulaires ou sur des cellules isolées à partir de patients, et, in vivo, dans des modèles de xénogreffe chez la souris immunodéprimée. Depuis quelques années, les contraintes réglementaires (règle des 3R : réduire, raffiner, remplacer) imposent de mettre en place des modèles alternatifs qui se substituent aux modèles murins ou, au moins, en limitent l’utilisation. Parmi les modèles alternatifs proposés, la greffe sur membrane chorio-allantoïdienne d’embryon de poule semble performante. Elle permet de suivre et de quantifier la croissance tumorale et d’autres paramètres associés, comme la néo-angiogenèse, l’invasion et la migration tumorales. Elle permet aussi le criblage de drogues. Ce modèle semble également adapté à la médecine personnalisée en cancérologie. Nous présentons dans cette revue la technique et ses avantages.
Scoop : les mutations « synonymes » ne sont pas neutres !
Authors: Jordan Bertrand
Published: October 2022

An ingenious system for generating thousands of point mutations in yeast genes and measuring their effect on fitness shows convincingly that, for the chosen subset of representative non-essential genes, silent mutations have as much effect on fitness as missense mutations. In other words, silent mutations are not neutral, at least under these conditions. This result has important implications for evolutionary biology.
L’actualité scientifique vue par les étudiants du Master Biologie Santé de l’université de Montpellier
Authors: Avinens Damien , Cantaloube Guilhem , Fortuin Annemarie , Hornebeck Joëlle , Jégou Paul , Marchal Lila , Pinceloup-Sosa Laura , Revel Justine , Sarrazin Louis , Sauthon Benjamin , Vincent Jéremy
Published: October 2022

L’unité d’enseignement « Immunopathologie » qui propose les brèves présentées dans ce numéro est suivie par des étudiants de divers parcours du Master Biologie Santé de l’université de Montpellier. Ce Master rassemble des étudiants issus du domaine des sciences et technologies et de celui de la santé. On y étudie les bases physiopathologiques des maladies immunologiques, les cibles thérapeutiques et les mécanismes d’échappement des microorganismes et des tumeurs. Les articles présentés ici ont été choisis par les étudiants selon leur domaine de prédilection.
Lebensgeschichtliche Interviews mit DDR-PsychotherapeutInnen
Authors: Kirschner Hariet , Arp Agnès , Schneider Nico , Storch Monika , Rauschenbach Manuel , Strauß Bernhard
Published: October 2022

Ziel der Studie Es werden erste Ergebnisse einer sozio-historischen
Betrachtung der Lebensgeschichten von DDR-PsychotherapeutInnen vorgestellt. Die
im Rahmen des Projektes Seelenarbeit im Sozialismus
durchgeführten Interviews sollen Aussagen zu sozialen und
familiären Hintergründen, Bildungswegen und gesellschaftlicher
Position ermöglichen. Ein exemplarischer Fall wird vorgestellt, um
Hypothesen zur Ausgestaltung professionellen Handelns von
DDR-PsychotherapeutInnen zu entwickeln.

Methode Narrative/biographische Interviews werden als Quelle
für historische und soziologische Forschungsstrategien aufbereitet.
Für eine deskriptive Darstellung der in den Interviews geschilderten
Themen wurde induktiv ein fallübergreifendes Kategoriensystem erstellt,
das Aussagen zur Häufigkeit bestimmter Charakteristika
ermöglichen soll. Der hier beschriebene Einzelfall wird anhand der
Methode der Grounded Theory analysiert.

Ergebnisse Ein erster Überblick über die Stichprobe
bezieht sich auf demographische Merkmale der interviewten Personen, ihren
Bekanntheitsgrad und die berufliche Qualifikation. Die interviewten
PsychotherapeutInnen lassen sich bezüglich ihrer Geburtsjahre
unterschiedlichen Dekaden der historischen Entwicklung der DDR-Psychotherapie
zuordnen und werden im Hinblick auf ihre soziale Herkunft (Elternberufe), ihre
berufliche Laufbahn (Verteilung der Qualifikationswege), ihre
Parteimitgliedschaft (SED bzw. Blockpartei) und erlebte Benachteiligungen durch
den Staat charakterisiert. Im Fallbeispiel wird die Abhängigkeit der
professionellen Haltung von sozialisatorischen Einflüssen verdeutlicht.

Diskussion In der Studie kann letztlich eine heterogene Gruppe von
PsychotherapeutInnen der DDR dargestellt werden, über deren Biographien
die historische Entwicklung der Psychotherapie in der DDR nachgezeichnet werden
kann. Mit Blick in die Herkunftsfamilien der Akteure zeigt sich, dass die Berufe
der Väter überproportional häufig im Bereich der
selbstständigen Unternehmer sowie Akademiker angesiedelt waren. Zudem
waren nur wenige PsychotherapeutInnen der Stichprobe Mitglied in der SED,
dafür werden jedoch häufige Benachteiligungen durch den Staat
benannt. Als Schlussfolgerung der Falldarstellung kann eine hohe Bedeutung von
Reflexivität aufgewiesen werden. Dies weist auf ein reflexives
professionelles Selbstverständnis hin.

Schlussfolgerung Weitere Auswertungen sollen Hypothesen zur
gesellschaftlichen und politischen Positionierung sowie zum professionellen
Selbstverständnis von DDR-PsychotherapeutInnen prüfen.
Einheit ist Stärke – die unterschätzte Kraft
der Sehnen bei einer Pseudarthrose
Authors: Fuest Lena , Noser Ladina , Bignion Dietmar , Vögelin Esther
Published: October 2022

Fallbericht

Bei einem Sturz beim Fußballspielen zog sich der gesunde, damals 38 Jahre
alte Patient eine skapholunäre (SL-) Bandläsion links zu. In
Folge waren innerhalb von sieben Jahren insgesamt 13 operative Eingriffe
nötig, bis eine vollständige Konsolidation der zuletzt angestrebten
Skapho-Trapezio-Trapezoidal-(STT)-Arthrodese erreicht wurde. 5 Jahre nach der
Verletzung auf der linken Seite kam es im Rahmen eines Distorsionstraumas
rechts ebenfalls zu einer SL-Bandverletzung bei dem Patienten. Bei einem
Stadium Geissler III wurde in einem auswärtigen Spital eine dynamische
Stabilisierung mit einer ECRL-Sehnenplastik durchgeführt. Bei zunehmender
SL-Dissoziation wurde aufgrund der Erfahrung mit der gleichen Problematik links
schlussendlich eine Panarthrodese des rechten Handgelenkes vorgenommen.
Pd-G3 XantPhos Mediated Approach to Bis-arylsulfenyl-benzo-2,1,3-thiadiazoles under Microwave Irradiation in DMF: Synthesis and Fluorescent Properties
Authors: Katla Ramesh , Katla Rakhi , Oreste Eliézer Quadro , Kessler Felipe
Published: October 2022

Synthesis of bis-arylsulfenyl-benzo-2,1,3-thiadiazoles was accomplished using a Pd-G3 XantPhos as a simple and inexpensive catalyst. Numerous benzene thiols reacted well with 4,7-dibromo-benzo-2,1,3-thiadiazole in DMF, using K2CO3 as the base, obtaining high product yields in a short reaction time. All the synthesized compounds showed remarkable fluorescence properties with emission wavelengths in the visible range. Due to their unique properties, these compounds have potential for application as image probes in fluorescence microscopy. The study found that these compounds have a wide range of potential uses in the area of sensors, as well as displaying other useful photophysical properties.
Laparoscopic versus Open Inguinal Hernia Repair Is Feasible in Infants with Caudal Anesthesia and Spontaneous Respiration
Authors: Kiblawi Rim , Beck Christiane , Keil Oliver , Schukfeh Nagoud , Hofmann Alejandro Daniel , Ure Benno Manfred , Kuebler Joachim Friedrich
Published: October 2022

Introduction Minimally invasive surgery (i.e., laparoscopy) and minimally invasive anesthesia (i.e., caudal anesthesia with spontaneous respiration) have separately shown benefits for inguinal hernia repair in infants, yet to what degree these techniques can be combined remains unknown. This study investigated whether laparoscopy impacts the feasibility of performing caudal anesthesia with spontaneous respiration in infants.

Methods Prospectively collected data of all infants less than 12 months old and over 3 kg weight who underwent laparoscopic indirect hernia repair (LAP) at our department from 2019 to 2021 were compared with a historical control-matched group of infants who underwent open repair (OPEN) from 2017 to 2021. We assessed the patients' characteristics, anesthesia, and surgical data as well as intra- and postoperative complications.

Results A total of 87 infants were included (LAP n = 29, OPEN n = 58). Caudal anesthesia with spontaneous respiration was feasible in 62.1% of cases (LAP n = 55.2%, OPEN n = 65.5%; nonsignificant). Neither group registered anesthetic intra- or postoperative complications. Sedatives were utilized in 97% of LAP patients versus 56.9% of OPEN patients (p < 0.00001). The airway was secured with a laryngeal mask in 89.7% of patients during LAP versus 41.4% during OPEN (p < 0.00001). No significant differences were found regarding the use frequency of opioids (48.3% LAP vs. 34.5% OPEN; nonsignificant) or neuromuscular blockers (6.9% LAP vs. 5.2% OPEN; nonsignificant).

Conclusion This is the first comparative study on caudal anesthesia and spontaneous respiration in infants undergoing laparoscopic versus open inguinal hernia surgery. Laparoscopy increased the need for ventilatory support and sedatives but did not significantly impair the feasibility of caudal anesthesia and spontaneous respiration.
Abutment on Titanium-Base Hybrid Implant: A Literature Review
Authors: Moreno André Luiz de Melo , dos Santos Daniela Micheline , Bertoz André Pinheiro de Magalhães , Goiato Marcelo Coelho
Published: October 2022

An increase in the use of Computer-Aided Design (CAD) and Computer-Aided Manufacturing (CAM) technologies challenges the conventional prosthetic fabrication procedures that are practical and centered on a digital workflow for the patient, especially for dental implants. Increasing workflow of digital restoration work, considering computer-used CAM for restoration technology systems and also fast/CAM for building restoration technology; fast/CAD, also known as abut-Base, has increased interest. Studies on adaptation of different restorative materials, on titanium (Ti)-base abutments, traction, and transformed cycling have become relevant. The objective of this work was to research, through literature studies, on restoration-type abutments. A total of 24 articles were found after searching the following terms in PubMed/Medline, Scopus, and Embase databases: “ti-base AND abutment.” Twenty-one manuscripts selected from the inclusion and exclusion criteria. After an analysis of these articles, it was concluded that the Ti-base abutment and components from the same manufacturer as the Implant should be used preferably; milled monolithic crowns designed to adapt to the Ti-base the hybrid abutment-crown assembly does not affect torque maintenance after thermal aging; the saliva and cleaning protocol of the Ti-base bonding surfaces can influence the operations of the Ti-base crowns; Ti-base and Crown surface treatment is recommended for better applicability and stability results, and the superiority of resin-based cements compared with other types of cements.
The Effect of Gamma-Ray Irradiation on the Physical, Mechanical, and Morphological Characteristics of PVA-Collagen-Chitosan as a Guided Tissue Regeneration (GTR) Membrane Material
Authors: Komara Ira , Susanto Agus , Amaliya Amaliya , Abbas Basril , Warastuti Yessy , Hendiani Ina , Miranda Aldilla , Erliani Annisa Pranuditha
Published: October 2022

Objective The aim of this study was to evaluate the effect of gamma-ray irradiation on the physical, mechanical, and morphological characteristics of the polyvinyl alcohol (PVA)-collagen-chitosan membranes as a guided tissue regeneration membrane material.

Material and Method The membrane was fabricated by mixing PVA, collagen, and chitosan using the film casting method. PVA-collagen-chitosan membranes were irradiated with various radiation dose (0, 15, and 25 kGy). Furthermore, it is characterized using Fourier-transform infrared (FTIR) for functional group identification, morphological test was performed using scanning electron microscopy (SEM), and mechanical properties (i.e., tensile strength and elongation) were evaluated using universal testing machine and swelling studies.

Statistical Analysis Statistical analysis was performed based on analysis of variance and post hoc with p-value < 0.05.

Result The FTIR spectrum shows various peaks of functional groups from the PVA-collagen-chitosan membrane. The result of the statistical analysis show changes in tensile strength (p = 0.0004) and membrane elongation (p = 0.000451) at different radiation doses of 0, 15, and 25 kGy. The membrane absorption obtains p-value of 0.0193, while the SEM results show that the PVA-collagen-chitosan membrane homogeneously mixed.

Conclusion There is an effect of gamma-ray irradiation on tensile strength, elongation, and water absorption of the membranes. Increasing the radiation dose increases the value of tensile strength, while elongation and absorption of the membrane decrease. The PVA-collagen-chitosan membrane has the potential to develop as an alternative membrane for guided tissue regeneration.