bluuebunny/crossref_metadata_2025 huggingface dataset:
Operation Simulation and Economic Analysis of Household Hybrid PV and BESS Systems in the Improved TOU Mode
Authors: Zhao Ziyi
Published: May 2023

With the popularization of electric vehicles and electric boilers, household electricity consumption will increase significantly. Household hybrid photovoltaic (PV) systems and battery energy storage systems (BESSs) can supply increasing household electricity consumption without expanding the existing distribution network. This paper validates the technical feasibility of connecting a large number of household power users that contain BESSs and PVs in a distribution line by a simulation in Matlab. In addition to technical feasibility, this article improves the time-of-use (TOU) form to achieve economic feasibility (covering equipment costs). In the past, the TOU was set from the perspective of the load demand of the grid, but the actual user participation would affect this effect. In this paper, based on a social science survey, a new three-level rate TOU is introduced, which has little impact on residents’ lifestyle, to effectively increase the response frequency effectively. Combined with the improved TOU and the state of PVs, the BESS control mode is set for simulation. To compare the three-tier rate TOU with the normal TOU tariff and select the best household BESS size, a MATLAB simulation is used to simulate the common household BESS capacity. The results indicate that the combination of the three-tier rate TOU with a 4 kWh household BESS can afford the investment of household PVs and BESSs. The high cost issue that previously primarily limited the true use of BESSs is expected to be resolved.
Characteristics of Spatial–Temporal Differences and Measurement of the Level of Forestry Industry Integration in China
Authors: Jin Mingming , Chen Ni , Sun Haisheng , Cao Fangping
Published: May 2023

The integration of the forestry industry can effectively resolve the conflict between ecological protection and socioeconomic development while bringing new vitality and growth to traditional forestry. In this study, the level of forestry industry integration in 31 provinces in China from 2005 to 2019 was measured using the Herfindahl index method. With ArcGIS and exploratory spatial data analysis methods, the spatial-temporal distribution characteristics, dynamic change trends, spatial correlation characteristics, and existing problems in China’s forestry industry integration development were analyzed. The results showed that the total output value of forestry integrated products and the output value of each product segment increased, but the proportion of product development was imbalanced, and it was concentrated in the understory planting and collection industry and wood processing and manufacturing industry, leaving substantial room for improvement and integration. The value of the forestry industry integration index also increased overall, but the level of integration was low or moderate. In terms of time, the integration index of most provinces trended upward but failed to break through 0.73, leaving a significant gap between it and deep integration. Spatially, the level of integration of the forestry industry varied across the northeast, central, west, and east, with the central and northeast showing a higher integration degree than the east and west. China’s forestry industry integration showed a significant positive spatial correlation, indicating that spatial factors had become an important factor affecting the development of the forestry industry in various regions. Therefore, it is necessary to strengthen the relevant mechanisms of cross-border cooperation and benefit sharing. Lastly, we identified problems with the integration development of the forestry industry, including insufficient and imbalanced integration, unreasonable structural layout of integration development, and insufficient driving capacity for integration. As a result, there were phased and regional differences in the evolution of forestry industry integration.
Signs of Use Present a Barrier to Reusable Packaging Systems for Takeaway Food
Authors: Collis Ben , Baxter Weston , Baird Harriet M. , Meade Keelan , Webb Thomas L.
Published: May 2023

Single-use packaging is one of the biggest contributors to plastic waste, and reuse has been identified as a key strategy to reduce such waste. However, reusable containers typically become worn, which may influence how consumers think and feel about reuse. The present research explored whether and how evaluations of a takeaway food service changed depending on the appearance of a reusable container. Two studies were conducted (using opportunity sampling) to (i) investigate the effects that signs of use have on people’s perceptions of reusable packaging systems using quantitative methods (Study 1) and (ii) understand the rationale underpinning these evaluations using qualitative methods (Study 2). Study 1 involved an online questionnaire where participants (n = 292) were shown images of reusable bowls for takeaway food with various levels of staining and asked to evaluate the container and the restaurant serving the food using rating scales. Study 2 involved in-person interviews where participants (n = 22) were given the opportunity to inspect either a clean bowl or a stained bowl and then were asked questions about the bowls. Signs of previous use seemed to undermine people’s willingness to reuse containers in the future and were associated with more negative evaluations of the packaging, product, and restaurant serving the food. These findings provide insights into the factors that affect people’s willingness to engage with reusable packaging systems, and we use these findings to suggest behavioural and design interventions that might mitigate negative evaluations and encourage reuse.
The Impact of COVID-19 on Supply Chain in UAE Food Sector
Authors: Abu Nahleh Yousef , Al Ali Budur , Al Ali Hind , Alzarooni Shouq , Almulla Shaikha , Alteneiji Fatima
Published: May 2023

The COVID-19 outbreak has significantly impacted supply chains and has caused several supply chain disruptions in almost all industries worldwide. Moreover, increased transportation costs, labor shortages, and insufficient storage facilities have all led to food loss during the pandemic, and this disruption has affected the logistics in the food value chain. As a result, we examine the food supply chain, which is one of the key industries COVID-19 has detrimentally affected, impacting, indeed, on the entire business process from the supplier all the way to the customer. Retail businesses are thus facing supply issues, which affect consumer behavior by creating stress regarding the availability of food. This has a negative impact on the amount of food that is available as well as its quality, freshness, safety, access to markets, and affordability. This study examines the impact of COVID-19 on the United Arab Emirates food distribution systems and how consumer behavior changed in reaction to interruptions in the food supply chain and the food security problem. Hypothesis testing was used in the study’s quantitative methodology to assess consumer behavior, and participants who were consumers were given a descriptive questionnaire to ascertain whether the availability and security of food had been impacted. The study used JASP 0.17.2 software to develop a model of food consumption behavior and to reveal pertinent connections between each construct. Results show that consumer food stress and consumption behavior are directly impacted by food access, food quality and safety, and food pricing. Furthermore, food stress has an impact on how consumers behave when it comes to consumption. Food stress, however, is not significantly influenced by food supply.
Analysing the Barriers Involved in Recycling the Textile Waste in India Using Fuzzy DEMATEL
Authors: Ponnambalam S. G. , Sankaranarayanan Bathrinath , Karuppiah Koppiahraj , Thinakaran Shakthi , Chandravelu Pranesh , Lam Hon Loong
Published: May 2023

Post-consumer wastes from the textile industry are generally landfilled or incinerated. The dumping of large amounts of textile waste has resulted in severe environmental problems. Advancements in technologies have called for textile recycling; however, the level of embracement made by the textile industry towards textile recycling is hampered by myriad factors. The scope of this study lies in identifying and analyzing multiple barriers to implementing textile recycling in India, encompassing all subsets of sustainability, i.e., social, economic, and environmental. The barriers are then evaluated using a Multiple Criteria Decision Making (MCDM) approach to identify the significant barriers. A trapezoidal fuzzy-DEMATEL methodology was executed to not only find the most influential barriers but also to find the cause-effect nature between every barrier. The outcome of the study indicates a lack of successful recycling business models, poor demand for recycled textiles goods, recycled products may not replace new products, lack of support for waste management in the industry, and absence of tax relief and rewarding policies as the top five barriers to textile waste recycling. This insight could help influence the decision of future policymakers in the field. Another aspect of the issue of pollution in the textile industry is the recent trend of fast fashion and the enormous amount of waste produced by overconsumption. The Sustainability Development Goal (SDG) 12 which is to ensure responsible production and consumption plays a key role in this sector.
Characterization of Ricci Almost Soliton on Lorentzian Manifolds
Authors: Li Yanlin , Kumara Huchchappa A. , Siddesha Mallannara Siddalingappa , Naik Devaraja Mallesha
Published: May 2023

Ricci solitons (RS) have an extensive background in modern physics and are extensively used in cosmology and general relativity. The focus of this work is to investigate Ricci almost solitons (RAS) on Lorentzian manifolds with a special metric connection called a semi-symmetric metric u-connection (SSM-connection). First, we show that any quasi-Einstein Lorentzian manifold having a SSM-connection, whose metric is RS, is Einstein manifold. A similar conclusion also holds for a Lorentzian manifold with SSM-connection admitting RS whose soliton vector Z is parallel to the vector u. Finally, we examine the gradient Ricci almost soliton (GRAS) on Lorentzian manifold admitting SSM-connection.
Strategies to Prevent Suicide and Attempted Suicide in New South Wales (Australia): Community-Based Outreach, Alternatives to Emergency Department Care, and Early Intervention
Authors: Goldberg Eileen , Peng Cindy , Page Andrew , Bandara Piumee , Currie Danielle
Published: May 2023

Background: This study describes the development of a system dynamics model to project the potential impact of a series of proposed suicide prevention interventions in New South Wales (NSW, Australia) over the period 2016 to 2031. Methods: A system dynamics model for the NSW population aged ≥ 20 years which represented the current incidence of suicide and attempted suicide in NSW was developed in partnership with a consortium of stakeholders, subject matter experts, and consumers with lived experience. Scenarios relating to current suicide prevention initiatives were investigated to identify the combination of interventions associated with the largest reductions in the projected number of attempted suicide and suicide cases for a 5-year follow-up period (2019–2023). Results: The largest proportion of cases averted for both suicide and attempted suicide over the intervention period was associated with community-based suicide prevention outreach teams and peer-led drop-in facilities (6.8% for attempted suicide, 6.4% for suicide). A similar proportion of potential cases averted of both attempted suicide and suicide (6.4%) was evident for targeted interventions focusing only on those in the population with suicidal thoughts and a previous history of attempted suicide. Conclusion: Initiatives that are characterised by the short-term stabilisation of suicidal distress at the point of crisis, averting the need for a hospital encounter, and the referral of individuals to non-acute community-based care were associated with the largest potential reductions in suicidal behaviour in NSW.
From Bacterial Toxin to Therapeutic Agent: The Unexpected Fate of Mycolactone
Authors: Ricci Daniela , Demangel Caroline
Published: May 2023

“Recognizing a surprising fact is the first step towards discovery.” This famous quote from Louis Pasteur is particularly appropriate to describe what led us to study mycolactone, a lipid toxin produced by the human pathogen Mycobacterium ulcerans. M. ulcerans is the causative agent of Buruli ulcer, a neglected tropical disease manifesting as chronic, necrotic skin lesions with a “surprising” lack of inflammation and pain. Decades after its first description, mycolactone has become much more than a mycobacterial toxin. This uniquely potent inhibitor of the mammalian translocon (Sec61) helped reveal the central importance of Sec61 activity for immune cell functions, the spread of viral particles and, unexpectedly, the viability of certain cancer cells. We report in this review the main discoveries that marked our research into mycolactone, and the medical perspectives they opened up. The story of mycolactone is not over and the applications of Sec61 inhibition may go well beyond immunomodulation, viral infections, and oncology.
Acute Phase Proteins in Dogs with Natural Infection by Trypanosoma cruzi
Authors: Rivadeneira-Barreiro Pilar , Montes-de-Oca-Jiménez Roberto , Zambrano-Rodríguez Pablo , Vázquez-Chagoyán Juan Carlos , Gutiérrez-Castillo Adriana del Carmen , Pardo-Marin Luis , Franco-Martínez Lorena , Cerón José Joaquín , Martínez-Subiela Silvia
Published: May 2023

Acute phase proteins have been used as tools for the diagnosis, monitoring, and prognosis of several diseases in domestic animals. However, the dynamics of these proteins in infection by Trypanosoma cruzi, the causative agent of Chagas disease in dogs, is still unknown. The aim of this study was to determine concentrations of acute phase proteins (C-reactive protein, haptoglobin, ferritin and paraoxonase-1) in dogs in a coastal town of Ecuador, with natural Trypanosoma cruzi infection with or without seroreactivity of Ehrlichia canis, Ehrlichia ewingii, Anaplasma phagocytophilum, Anaplasma platys, Borrelia burgdorferi and Dirofilaria immitis. For the detection of Trypanosoma cruzi serum antibodies, two different antigen-based enzyme-linked immunosorbent assay tests were implemented. For the detection of seroreactivity of Ehrlichia canis, Ehrlichia ewingii, Anaplasma phagocytophilum, Anaplasma platys, Borrelia burgdorferi and Dirofilaria immitis, an IDEXX SNAP® 4Dx® test was used. To determine the concentration of C-reactive protein and ferritin, an immunoturbidimetric assay was used; haptoglobin concentration was measured using a commercial colorimetric method validated in dogs; a spectrophotometric method was used to determine the serum concentration of paraoxonase-1. Results showed a reduction in the serum levels of paraoxonase-1 in Trypanosoma cruzi-seroreactive dogs, either with or without seroreactivity to other vector-borne diseases. A serum ferritin increment was observed in Trypanosoma cruzi-seroreactive dogs with seroreactivity to any other vector-borne diseases. Our findings suggest that paraoxonase-1 levels are reduced in Trypanosoma cruzi-seroreactive dogs without evident clinical signs of Chagas disease, despite their seroreactivity to the other vector-borne diseases studied. These findings could indicate an oxidative stress response in Trypanosoma cruzi-seroreactive dogs with no evident signs of inflammation.
Under-Reporting of Tuberculosis Disease among Children and Adolescents in Low and Middle-Income Countries: A Systematic Review
Authors: Linn Alexandra R. , Dubois Melanie M. , Steenhoff Andrew P.
Published: May 2023

Under-reporting of tuberculosis (TB) disease in children and adolescents is a significant global concern, as many children are missing from TB notification data. A systematic literature review was conducted to understand the global reporting gap of child and adolescent TB as well as current interventions to close this gap in Low- and Middle- Income Countries (LMIC). Our study found large and variable gaps in child and adolescent TB reporting, due to various factors. Interventions to close this gap exist but are limited. Future studies are necessary to improve global surveillance systems to improve TB care delivery for children and adolescents.
Epidemiology and Economic Burden of Chikungunya: A Systematic Literature Review
Authors: Costa Lourrany Borges , Barreto Francisca Kalline de Almeida , Barreto Marina Carvalho Arruda , Santos Thyago Henrique Pereira dos , Andrade Maria de Margarette Oliveira de , Farias Luís Arthur Brasil Gadelha , Freitas André Ricardo Ribas de , Martinez Miguel Julian , Cavalcanti Luciano Pamplona de Góes
Published: May 2023

Chikungunya (CHIK) is a re-emerging viral infection endemic in tropical and subtropical areas. While the typical clinical presentation is an acute febrile syndrome, long-term articular complications and even death can occur. This review characterizes the global epidemiological and economic burden of chikungunya. The search included studies published from 2007 to 2022 in MEDLINE, Embase, LILACS, and SciELO for a thorough evaluation of the literature. Rayyan software was used for data analysis, and data were summarized descriptively and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Seventy-six publications were included. Chikungunya is widely distributed in the tropics, including Africa, Asia, South America, and Oceania/the Pacific Islands, and co-circulates with other simultaneous arboviruses such as DENV, ZIKV, and YFV. Chikungunya infection can lead to chronic articular manifestations with a significant impact on the quality of life in the long term. In addition, it generates absenteeism and economic and social losses and can cause fatal infections in vulnerable populations, mainly in high-risk patients with co-morbidities and at the extremes of age. Reported costs associated with CHIKV diseases are substantial and vary by region, age group, and public/private delivery of healthcare services. The chikungunya disease burden includes chronicity, severe infections, increased hospitalization risks, and associated mortality. The disease can impact the economy in several spheres, significantly affecting the health system and national economies. Understanding and measuring the full impact of this re-emerging disease is essential.
Current Status and Complexity of Three Begomovirus Species in Pepper Plants in Lowlands and Highlands in Java Island, Indonesia
Authors: Wahyono Andi , Murti Rudi Hari , Hartono Sedyo , Nuringtyas Tri Rini , Wijonarko Arman , Mulyantoro Mulyantoro , Firmansyah Deni , Afifuddin Ahmad , Purnama Innez Candri Gilang
Published: May 2023

Three primary species from the Begomovirus genus, Pepper yellow leaf curl Indonesia virus (PepYLCIV), Tomato yellow leaf curl Kanchanaburi virus (TYLCKaV), and Tomato leaf curl New Delhi virus (ToLCNDV), are suspected of spreading throughout pepper production centers, and plants are infected by a single species or a combination of two or three species. This study was conducted to provide complete information about the symptoms, incidence and severity, whitefly biotypes, as well as the dominance status of the three Begomovirus species in pepper-producing areas in Java. A DNA analysis was carried out on leaf samples to identify Begomovirus species and biotypes of B. tabaci collected from 18 areas (16 districts) in lowlands (<400 m asl) and highlands (>700 m asl). The DNA analysis showed that B. tabaci biotype B was the most commonly detected in all locations compared to the A, AN, and Q biotypes. The incidence of begomovirus infection was at a high level, 93% and 88.78% in the lowlands and highlands, respectively. However, the severity of begomovirus infection was significantly higher in the lowlands (54.50%) than in the highlands (38.11%). A single infection of PepYLCIV was most dominant in all locations sampled and caused severe infection, followed by a mixed infection with TYLCKaV. Therefore, the current status of begomovirus infection, especially PepYLCIV, can provide advice to farmers using more tolerant and resistant varieties as well as a breeding strategy for resistant pepper varieties.
Generation of a SARS-CoV-2 Reverse Genetics System and Novel Human Lung Cell Lines That Exhibit High Virus-Induced Cytopathology
Authors: Khan Juveriya Qamar , Rohamare Megha , Rajamanickam Karthic , Bhanumathy Kalpana K. , Lew Jocelyne , Kumar Anil , Falzarano Darryl , Vizeacoumar Franco J. , Wilson Joyce A.
Published: May 2023

The global COVID-19 pandemic continues with continued cases worldwide and the emergence of new SARS-CoV-2 variants. In our study, we have developed novel tools with applications for screening antivirals, identifying virus–host dependencies, and characterizing viral variants. Using reverse genetics, we rescued SARS-CoV-2 Wuhan1 (D614G variant) wild type (WTFL) and reporter virus (NLucFL) using molecular BAC clones. The replication kinetics, plaque morphology, and titers were comparable between viruses rescued from molecular clones and a clinical isolate (VIDO-01 strain). Furthermore, the reporter SARS-CoV-2 NLucFL virus exhibited robust luciferase values over the time course of infection and was used to develop a rapid antiviral assay using remdesivir as proof-of-principle. In addition, as a tool to study lung-relevant virus–host interactions, we established novel human lung cell lines that support SARS-CoV-2 infection with high virus-induced cytopathology. Six lung cell lines (NCI-H23, A549, NCI-H1703, NCI-H520, NCI-H226, and HCC827) and HEK293T cells were transduced to stably express ACE2 and tested for their ability to support virus infection. A549ACE2 B1 and HEK293TACE2 A2 cell lines exhibited more than 70% virus-induced cell death, and a novel lung cell line, NCI-H23ACE2 A3, showed about ~99% cell death post-infection. These cell lines are ideal for assays relying on live–dead selection, such as CRISPR knockout and activation screens.
Plant Poly(ADP-Ribose) Polymerase 1 Is a Potential Mediator of Cross-Talk between the Cajal Body Protein Coilin and Salicylic Acid-Mediated Antiviral Defence
Authors: Spechenkova Nadezhda , Samarskaya Viktoriya O. , Kalinina Natalya O. , Zavriev Sergey K. , MacFarlane S. , Love Andrew J. , Taliansky Michael
Published: May 2023

The nucleolus and Cajal bodies (CBs) are sub-nuclear domains with well-known roles in RNA metabolism and RNA-protein assembly. However, they also participate in other important aspects of cell functioning. This study uncovers a previously unrecognised mechanism by which these bodies and their components regulate host defences against pathogen attack. We show that the CB protein coilin interacts with poly(ADP-ribose) polymerase 1 (PARP1), redistributes it to the nucleolus and modifies its function, and that these events are accompanied by substantial increases in endogenous concentrations of salicylic acid (SA), activation of SA-responsive gene expression and callose deposition leading to the restriction of tobacco rattle virus (TRV) systemic infection. Consistent with this, we also find that treatment with SA subverts the negative effect of the pharmacological PARP inhibitor 3-aminobenzamide (3AB) on plant recovery from TRV infection. Our results suggest that PARP1 could act as a key molecular actuator in the regulatory network which integrates coilin activities as a stress sensor for virus infection and SA-mediated antivirus defence.
Unraveling the Molecular and Cellular Pathogenesis of COVID-19-Associated Liver Injury
Authors: Akkiz Hikmet
Published: May 2023

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) continues to cause substantial morbidity and mortality. Most infections are mild; however, some patients experience severe and potentially fatal systemic inflammation, tissue damage, cytokine storm, and acute respiratory distress syndrome. Patients with chronic liver disease have been frequently affected, experiencing high morbidity and mortality. In addition, elevated liver enzymes may be a risk factor for disease progression, even in the absence of underlying liver disease. While the respiratory tract is a primary target of SARS-CoV-2, it has become evident that COVID-19 is a multisystemic infectious disease. The hepatobiliary system might be influenced during COVID-19 infection, ranging from a mild elevation of aminotransferases to the development of autoimmune hepatitis and secondary sclerosing cholangitis. Furthermore, the virus can promote existing chronic liver diseases to liver failure and activate the autoimmune liver disease. Whether the direct cytopathic effects of the virus, host reaction, hypoxia, drugs, vaccination, or all these risk factors cause liver injury has not been clarified to a large extent in COVID-19. This review article discussed the molecular and cellular mechanisms involved in the pathogenesis of SARS-CoV-2 virus-associated liver injury and highlighted the emerging role of liver sinusoidal epithelial cells (LSECs) in virus-related liver damage.
Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes
Authors: Kokinos Elena K. , Tsymbal Sergey A. , Galochkina Anastasia V. , Bezlepkina Svetlana A. , Nikolaeva Julia V. , Vershinina Sofia O. , Shtro Anna A. , Tatarskiy Victor V. , Shtil Alexander A. , Broude Eugenia V. , Roninson Igor B. , Dukhinova Marina
Published: May 2023

Hyperactivation of the immune system remains a dramatic, life-threatening complication of viral and bacterial infections, particularly during pneumonia. Therapeutic approaches to counteract local and systemic outbreaks of cytokine storm and to prevent tissue damage remain limited. Cyclin-dependent kinases 8 and 19 (CDK8/19) potentiate transcriptional responses to the altered microenvironment, but CDK8/19 potential in immunoregulation is not fully understood. In the present study, we investigated how a selective CDK8/19 inhibitor, Senexin B, impacts the immunogenic profiles of monocytic cells stimulated using influenza virus H1N1 or bacterial lipopolysaccharides. Senexin B was able to prevent the induction of gene expression of proinflammatory cytokines in THP1 and U937 cell lines and in human peripheral blood-derived mononuclear cells. Moreover, Senexin B substantially reduced functional manifestations of inflammation, including clustering and chemokine-dependent migration of THP1 monocytes and human pulmonary fibroblasts (HPF).
Pilot Study of Oxic–Anoxic Process under Low Dissolved Oxygen for Nitrogen Removal from Low COD/N Tropical Wastewater
Authors: Leong Chew Lee , How Seow Wah , Rabuni Mohamad Fairus , Mohd Aris Alijah , Khor Bee Chin , Curtis Thomas P. , Chua Adeline Seak May
Published: May 2023

Conventionally, nitrification in biological nitrogen removal (BNR) requires high dissolved oxygen (DO) concentrations (>2 mg L−1), making the process energy intensive. Recent studies have shown that efficient ammonium removal and energy reduction can be realized by operating the nitrification at low DO concentrations (<1 mg L−1). In this study, the low-DO oxic anoxic (low-DO OA) process was operated in a pilot-scale sequencing batch reactor (SBR) over 218 days to evaluate the feasibility of nitrogen removal from low chemical oxygen demand-to-nitrogen ratio (COD/N) tropical municipal wastewater. The results revealed that the low-DO OA process attained high removal efficiency for ammonium (97%) and total nitrogen (TN) (80%) under an average DO concentration of 0.6 mg L−1. The effective TN removal efficiency is attributed to the occurrence of simultaneous nitrification–denitrification (SND) under low DO conditions. Further batch tests revealed that slowly biodegradable COD (sbCOD) in tropical wastewater can support denitrification in the post-anoxic phase, resulting in a high TN removal rate. Compared with high DO concentrations (2 mg L−1), low DO conditions achieved 10% higher TN removal efficiency, with similar ammonium and COD removal efficiency. This study is crucial in promoting the energy efficiency and sustainability of wastewater treatment plants treating low COD/N wastewater.
Indication of Long-Term Changes of Algae Communities in a Hydrologically Transformed Estuary Sasyk, Black Sea, Ukraine
Authors: Bilous Olena P. , Wojtal Agata Z. , Ivanova Natalia O. , Burova Olga V. , Barinova Sophia , Maystrova Nadiya V. , Polishchuk Oleksandr , Curtean-Bănăduc Angela , Tsarenko Petro M.
Published: May 2023

Forty years ago, the transformation of the estuary of the Black Sea to a freshwater reservoir was started by its connection with the Danube River through the Danube–Sasyk Canal. Today, the inflow of the Danube water into the Sasyk is the main component of the water balance, affecting the internal and external water exchange, and it is, in general, responsible for the quality of the aquatic environment. In addition, the channel is a migration route for hydrobionts and the main source of invasion. We describe the changes in the composition of algal communities in Sasyk, which was converted from an estuary to a reservoir during three stages: estuary-lake in 1967–1977 (stage I), the forming of the reservoir from 1980–1990 (stage II), and the reservoir from 2013–2019 (stage III). Average salinity decreased from 7790 to 491 mg L−1 chlorides, and the species richness of algae increased from 259 to 289 taxa during the Sasyk transformation. Analysis of the algal communities revealed that salinity could have an effect on their composition. The species list for the Sasyk, including 586 taxa of algae and cyanobacteria (613 infraspecific taxa), is presented here for the first time. Rare marine and freshwater taxa present in the algal community at the modern stage of the reservoir and their transformation are discussed. An ecological analysis of the different stages of the Sasyk transformation from an estuary into a reservoir was conducted. The increase in species richness for stages II and III along with an increase in desalination was noted. To keep the current ecological status of the reservoir and its hydrological stability, the role of the Danube River should be considered. Bioindicators, statistical analysis of species, and environmental variables’ relationships confirm salinity as a major regulating factor that can be observed by way of long-term monitoring.
Riga-Fede disease: a review of the literature and a description of clinical cases
Authors: Fomenko I. V. , Maslak E. E. , Kasatkina A. L. , Bavlakova V. V. , Fursik D. I.
Published: May 2023

Relevance.Riga-Fede disease (RFD) is a rare pathology that develops as a result of trauma to the mucous membrane of the tongue ventral surface with sharp edges of natal, neonatal or primary teeth erupting in time and manifests in the form of erosion or sublingual fibrous lesion with an ulcerated surface.

Purpose. To analyze the literature and present our own RFD clinical cases.

Material and methods.A search was performed of articles published in 2001-2023 on the research topic in the main scientific literature databases (PubMed, E-library, Google Scholar, etc.). We analyzed the data from 68 publications and presented three of our own clinical cases of RFD in children aged 5, 6 and 9 months.

Results.Analysis of literature data revealed different approaches to the diagnosis and treatment of RFD in children. The diagnosis of RFD should rely on the clinical picture and exclude additional trauma to children by histological examination and lesion excision. Pronounced tooth mobility, ineffective infant feeding and the presence of neurological diseases in patients were the main indications for the extraction of teeth, which caused RFD development. In the absence of tooth mobility, non-surgical treatment methods should be preferable. In the presented clinical cases, erupted primary teeth caused BRF. In two cases, the treatment consisted of smoothing the sharp edges of the teeth and restoration with glass ionomer cement; in one case, a child with a neurological disease experienced extraction of lower central incisors. In all cases, recovery was within 3-4 weeks.

Conclusion.Once clinically diagnosed with RFD, treatment method choice should consider tooth mobility and the child's overall health.
La préposition contre à partir de la valeur «d’échange». Variation sémantique et régularité des opérations linguistiques
Authors: Peroz Pierre
Published: May 2023

L’objectif de l’auteur est d’établir que l’ensemble des emplois de la préposition contre ressortit à un fonctionnement unique. Il montre d’abord que les descriptions proposées jusqu’ici ne permettent pas de traiter l’ensemble de ces emplois de manière unifiée. En partant de la valeur «d’échange », et des différentes formes que cette valeur peut prendre, il définit ce marqueur comme la trace dans l’énoncé de «la réduction de l’altérité constitutive des termes X et Y qu ’il met en relation ». Dans la dernière partie, en appliquant successivement cette caractérisation aux autres valeurs de contre, il montre que la variation sémantique est irrégulière quand les principes qui la fondent sont eux réguliers.
Les prépositions spatiales par et à travers - convergences et divergences
Authors: Stosic Dejan
Published: May 2023

The prepositions par and à travers are often considered as synonyms. In this paper, I discuss the synonymy of par and à travers by analysing their spatial uses. I show on the one hand that these prepositions are similar in terms of their syntactic functions in the sentence and of the contexts in which they occur. On the other hand, I show that they are almost entirely different semantically. The main differences between the semantics of par and à travers are pinpointed through the analysis of the spatial relations which these two prepositions can express.
L’évolution sémantique de au-dessus
Authors: Van Grunderbeek Lieve
Published: May 2023

Si à l’origine au-dessus ne s’employait qu ’au sens figuré, de nos jours les sens figurés semblent être passés à l ’arrière-plan : c ‘est le sens spatial que nous considérons intuitivement comme prototypique et apte à expliquer, par métaphorisation, les emplois figurés . Cette évolution du figuré au spatial semble contredire l'hypothèse localiste et complique la tâche de décéler le sens protypique de la préposition.

Partant de la description de la préposition au-dessus par Vandeloise, nous déterminerons les conditions d'emploi de au-dessus à l’heure actuelle. Une étude diachronique nous permettra de décrire les étapes morphologiques et sémantiques successives et révélera que le sens spatial était tout de même présent dès le début, bien que de façon latente. Dès lors nous pouvons nous mettre sur une même ligne avec Vandeloise en décrivant le sens prototypique en termes spatiaux.
Face à la disette dans la profusion
Authors: Habert Benoît
Published: May 2023

Very large electronic textual data are becoming mainstream. The very notion of data is to be re-assessed. Two ways of gathering data are presented : on the Web via research engines or with information extraction techniques. The relationship between introspection and ‘real data’ is being examined. The role of models, whether quantitative or qualitative, is emphasized.
Le N quantité : un substantif (quantificateur) comme les autres ?
Authors: Benninger Céline
Published: May 2023

In this work, we will focus on some of the properties of the French noun of quantity. A few of the questions raised are the following : What is its ontological status, what is its meaning ? What are its sites of occurrences ? What is its position within the nominal category ? How is it located in regard to the substantives in general, and to the quantifiers in particular ? The different reflections carried out throughout this study, by pointing out that the noun of quantity is not a standard noun, will give some elements of answers to these questions.
La spécificité des traductions dans une société multiethnique
Authors: Zbant Ludmila
Published: May 2023

Cet article traite de la problématique de la formation des traducteurs et des interprètes de conférences en République de Moldova. Ce type de formation exige une harmonisation des contenus des programmes d'études et des compétences professionnelles avec l'évolution économique, sociale et culturelle du monde contemporain. Le problème se complexifie dans cette société multiethnique où cohabitent des Moldaves, des Ukrainiens, des Russes, des Gagaouzes, des Bulgares et d'autres minorités nationales. Dans cette situation, il faut créer, d'une part des conditions satisfaisantes pour la traduction intrasociale et interculturelle, c'est-à-dire la traduction à l'intérieur du pays pour les représentants des minorités ; d'autre part, vu les relations politiques, économiques et culturelles de la Moldova avec des partenaires étrangers, les traducteurs contribuent aux activités de médiation intersociale et interculturelle.
Harmonising the translation of EU documents, setting standards and norms : the case of Turkey
Authors: Altay Ayfer
Published: May 2023

The aim of this presentation is to show the steps taken to ensure the standardisation and consistency in translating EU documents in Turkey. The organisation, which deals with EU affairs in Turkey, is The Secretariat General for EU Affairs (EUSG). In order to cope with the translation and revision of the primary and secondary legislation, the capacity of the Translation Coordination Unit in EUSG was strengthened by an EU funded project in 2008. A glossary of approximately 7,000 terms was published to ensure the consistency in terminology used in translating the EU documents. Hacettepe University, conducted an EU funded project, TermTurk, in order to create awareness of terminology issues.
Les rapports aux normes et à la traduction dans les entreprises
Authors: Choremi Thiresia , Bothorel-Witz Arlette
Published: May 2023

This contribution, which is part of a research on management of multilingualism in companies (European project DYLAN -Language dynamics and management of diversity) seeks to analyze different types and forms of norms through epi-and metalinguistic discourse. On the one hand, it focuses on "translation of norms" in discourse in order to define the various levels of comprehensibility of norms (subjective or imagined norms, usage norms, prescriptive norms) in relation to practices, plurilingual competencies and language treatment. On the other hand, this contribution approaches the norms of translation, in order to bring to light the various manners to envisage translation. As far as the latter is considered as a tool that contributes to a commercial and/or communicational strategy or a way to adapt oneself to contingencies of the moment and to dread change, the ways of considering translation deserve observation and analysis. This double approach of norms aims, in fine, to determine how complex interrelations between different types and forms of norms appear in discourse about practices, competencies and language treatment.
Noms d’objets et noms d’événements : quelles frontières linguistiques ?
Authors: Huyghe Richard
Published: May 2023

This paper deals with the differences between nouns denoting objects (ONs) and nouns denoting events (ENs). ONs and ENs combine respectively with se trouver 'be (somewhere)' and avoir lieu 'take place', but there is not any simple morphological or syntactic property - such as the derivation of the noun, or the existence of an argument structure - that can account for their distinction. The semantic properties of both types of Ns are scrutinized, especially their spatial and temporal features of extension and location. It is shown that ENs are heterogeneous with respect to their spatial denotation, and that the main difference between ONs and ENs is the denotation of temporal entities.
Evaluation of a Simple Low-cost Intervention to Empower People with CKD to Reduce Their Dietary Salt Intake: OxCKD1, a Multicenter Randomized Controlled Trial
Authors: O'Callaghan Christopher A. , Camidge Clare , Thomas Rachel , Reschen Michael E. , Maycock Alison J. , Lasserson Daniel S. , Fox Robin A. , Thomas Nicholas P.B. , Shine Brian , James Tim
Published: May 2023

Key Points

A randomized controlled trial demonstrates that a simple and cheap 1-month intervention empowers people with CKD to lower their dietary salt intake.

The effect of the intervention persisted after the intervention finished.

Background

To evaluate the efficacy of a simple low-cost intervention to empower people with CKD to reduce their dietary salt intake.

Methods

A randomized controlled trial in primary and secondary care comparing the OxSalt care bundle intervention versus standard care for 1 month. Participants were people with CKD and an eGFR >20 ml/min per 1.73 m2 and were recruited from primary and secondary care. The primary outcome was a reduction in dietary salt intake, as assessed by 24-hour urinary sodium excretion, after 1 month of the intervention.

Results

Two hundred and one participants were recruited. Dietary salt intake, as assessed from 24-hour urine sodium excretion, fell by 1.9 (±2.9) g/d in the intervention group compared with 0.4 (±2.7) g/d in the control group (P < 0.001). Salt intake was still reduced to a lesser extent over the following year in the intervention group.

Conclusions

A short, low-cost, easily delivered intervention empowers people with CKD to reduce their dietary salt intake.

Trial registration

ClinicalTrials.gov NCT01552317.
Intravenous Antimicrobial Starts among Hemodialysis Patients in the National Healthcare Safety Network Dialysis Component, 2016–2020
Authors: Wilson W. Wyatt , Gouin Katryna A. , Fike Lucy , Apata Ibironke W. , Bell Jeneita M. , Edwards Jonathan R. , Novosad Shannon , Kabbani Sarah
Published: May 2023

Key Points

NHSN total IV antimicrobial start rates for patients on hemodialysis decreased from 2016 to 2020, but rates unsupported by NHSN surveillance documentation did not.

There were 80% of reporting hemodialysis facilities that had ≥1 unsupported IV antimicrobial start, and the fraction of facilities with unsupported starts increased yearly.

Accurate reporting and timely review of antimicrobial data is critical to understanding prescribing trends and practices in hemodialysis facilities.
A Deep Generative Model with Multiscale Features Enabled Industrial Internet of Things for Intelligent Fault Diagnosis of Bearings
Authors: Hu He-xuan , Cai Yicheng , Hu Qiang , Zhang Ye
Published: May 2023

Effective condition monitoring and fault diagnosis of bearings can not only maximize the life of rolling bearings and prevent unexpected shutdowns caused by equipment failures but also eliminate unnecessary costs and waste caused by excessive maintenance. However, the existing deep-learning-based bearing fault diagnosis models have the following defects. First of all, these models have a large demand for fault data. Second, the previous models only consider that single-scale features are generally less effective in diagnosing bearing faults. Therefore, we designed a bearing fault data collection platform based on the Industrial Internet of Things, which is used to collect bearing status data from sensors in real time and feed it back into the diagnostic model. On the basis of this platform, we propose a bearing fault diagnosis model based on deep generative models with multiscale features (DGMMFs) to solve the above problems. The DGMMF model is a multiclassification model, which can directly output the abnormal type of the bearing. Specifically, the DGMMF model uses 4 different variational autoencoder models to augment the bearing data and integrates features of different scales. Compared with single-scale features, these multiscale features contain more information and can perform better. Finally, we conducted a large number of related experiments on the real bearing fault datasets and verified the effectiveness of the DGMMF model using multiple evaluation metrics. The DGMMF model has achieved the highest value under all metrics, among which the value of precision is 0.926, the value of recall is 0.924, the value of accuracy is 0.926, and the value of F1 score is 0.925.
Investigating the Effect of Nozzle Diameter on Tensile Strength in 3D-Printed Printed Polylactic Acid Parts
Authors: KARTAL Fuat , KAPTAN Arslan
Published: May 2023

Three-dimensional (3D) printing is a rapidly evolving manufacturing technology that enables the production of intricate, customizable parts with a wide range of applications. The quality and mechanical properties of printed parts are heavily influenced by the process parameters, such as nozzle size. This study presents a comprehensive investigation of the effect of nozzle diameter on the tensile strength of 3D-printed polylactic acid (PLA) parts, focusing on six nozzle sizes: 0.3, 0.4, 0.5, 0.6, 0.7, and 0.8 mm. PLA, a commonly used thermoplastic in 3D printing, was employed as the material of choice. Using an open-source Fused Filament Fabrication (FFF) 3D printer, dog bone-shaped specimens were printed according to the ASTM D638-Type IV standard for tensile testing. The results reveal a strong correlation between nozzle size and tensile strength, with smaller nozzles producing parts with higher tensile strength due to finer layers and improved interlayer adhesion. However, the trade-off between tensile strength and printing time associated with smaller nozzle sizes must be considered when optimizing the 3D printing process for specific applications. This study provides essential insights into the influence of nozzle diameter on tensile strength, offering valuable guidance for achieving desired mechanical properties in 3D-printed parts.
Evaluation of SNPs and miRNAs in the BID, MAPK10, and AGER Genes Related to Alzheimer's Disease by Using In Silico Tools
Authors: DEMİRCİ Nur , ÖZKAN OKTAY Ebru , KARAHAN Mesut
Published: May 2023

Alzheimer's disease (AD) is a multifactorial disease resulting from both genetic and environmental factors, which are pathologically defined by the accumulation of intracellular hyperphosphorylated tau protein, neurofibrils tangles, and extracellular amyloid β protein in the brain. The purpose of this study is to estimate the potentially damaging effects of missense single nucleotide polymorphisms (SNPs) in the BID, MAPK10 and AGER genes associated with AD using various in silico tools and to determine the effects of SNPs on miRNAs. In addition, it is aimed to determine the gene-gene and protein-protein interactions through various software tools.
Consequently, it was estimated that there may be harmful effects of seven polymorphisms in the BID gene, twenty-seven in the MAPK10 gene and three in the AGER gene. It was obtained that some SNPs decrease the effectiveness of miRNA-mRNA binding, enhance, break, create a new binding zone and/or destroy the miRNA-mRNA binding zone in the BID and MAPK10 genes. miRNA-SNP analyses could not provide information on the AGER gene.
In this study, SNPs in the BID, MAPK10, and AGER genes, which are estimated to be high-risk SNPs, will be able to provide data for future genotyping studies. SNPs that are estimated to be high-risk and SNPs that may have a role in miRNA- mRNA activity can be assessed as a priority in experimental studies related to AD.
In the future, experimental studies are proposed to investigate the clinical effects of harmful/disease-related missense SNPs and SNPs affecting mRNA-miRNA interaction.
Some Matrix Applications on the Special Integer Number Sequences
Authors: AKBABA Ümmügülsün
Published: May 2023

In this paper, the matrices related to Fibonacci, Lucas, Pell, and Pell-Lucas numbers have been examined. By using these matrices new identities related to these integer sequences have been investigated.