bluuebunny/crossref_metadata_2025 huggingface dataset:
The Psychological Impacts of Diabetic Foot in Rural Population Patients
Authors: Muawia Ibrahim Abdelgadir , Salih Fardos Bushra Mohamed , Ahmed Sami Mustafa Jafar , Awadelgeed Bashir Ali
Published: January 2023

Purpose: This study aim to evaluate various psychiatric disorders (depression, anxiety and stress) associated with diabetic foot ulcers in rural population patients.

Methodology: The study design was Cross sectional study.  The sample was taken from rural area of White Nile state- Sudan   in august 2022.The sample was consisted of patients with  diabetic Foot (N=112), (male=59, female=53). DASS-21 was used to measure the depression, anxiety and stress.

Findings: The result observed that 44.56%, 44.32% and 49.11% of patients with diabetic foot were suffering between (Moderate to Extremely Severe) in depression, anxiety and stress respectively. The depression in female patients was significantly higher (M =12.0, SD =6.95) than the depression in male patients (M =10.0, SD = 5.89), but the anxiety in female patients was significantly lower (M = 9.5, SD = 4.51) than the anxiety in male patients (M = 11.5, SD = 3.697). The stress in female patients was significantly higher (M = 12.25, SD = 4.19) than the stress in male patients (M =10.25, SD = 4.57).

Unique contributions to theory, practice and policy: The study concluded that there was high prevalence of depression, anxiety and stress in patients with diabetic foot.
E-Governance in India: A Qualitative Analysis using the ABCD Framework and its Impact on Goodwill from Social Capital
Authors: lobo Alisha Edile , Noronha Sonia Delrose
Published: January 2023

Purpose: Electronic governance is the use of ICT applications to offer citizens, businesses, employees, other government agencies with government services that are simple, efficient, and transparent. This research paper aims to identify different types of government interaction in e-governance services, explore different e-governance models, their applications & impact on goodwill from social capital through e-governance.
Design/Methodology/Approach: This case study is developed on qualitative data collected from published sources. Information obtained from newspapers, journal articles, corporate & government websites, is used to provide in-depth analyses.
Findings: According to the study, the National e-Governance Plan (NeGP) of India intends to make government services more available to the general public. It also strives for efficiency, transparency, dependability, and effective service delivery at a reasonable cost. The plan is being put into action at the local, state, and federal levels.
Originality: This study emphasizes India’s E-governance through qualitative analysis using the ABCD framework based on different stakeholders’ points of view, i.e., government, citizens, businesses, and employees.
Paper Type: Case Study.
Theme of Resistance in The Prison We Broke and The Weave of My Life
Authors: Kanwar Rajni
Published: January 2023

In this paper I want to explore the theme of Resistance which is very common in Dalit writings. Sometimes their resistance is against the dominant class, sometimes it is against economic deprivation and the other time it is strongly against the age old caste system. Earlier Dalit Literature was not given a prominent place in the mainstream literature but by the efforts of Dalit writers this scenario has been changed. Today Dalit Literature has acquired a significant place amongst other literature. In fact, Dalit Literary Studies have also been introduced in several universities. The notion of Caste is very crucial for understanding the system of structural inequalities. Dalits have often been marginalized and oppressed in several ways. Therefore, it can be said that this discrimination was the major factor which gave birth to resistance. Although, the term “resistance” should not only be seen in a negative manner because sometimes  resistance is very essential in bringing up a social transformation in the society. I have selected two autobiographies namely The Prison We Broke and The Weave of My Life which are written by dalit female writers to depict the discriminatory system prevailed in the society and the harsh realities faced by dalit people. Autobiographies are generally considered personal narratives which provide a first-hand account of their experience and struggle for human dignity. For many Dalit writers literature has becomes a medium to raise their voice against the evil power of oppression and injustice. In their narratives they depict how their people have been exploited and treated inhumanly in everyday social life. Thus, these poor down trodden people ended up in a life full of pain and misery. In the last section I also want to discuss the role of B. R. Ambedkar in spreading awareness amongst the masses regarding their rights.  He believed that the role of education is very important for social emancipation and eliminating the discriminatory attitude of upper caste people.
Sosyal Bilgilerde Hukuk Okuryazarlığı: Sistematik Literatür Taraması
Authors: ÇETİN Mehmet
Published: January 2023

Toplumsal yaşamın devamlılığında ve sürdürülebilirliğinde önemli bir yere sahip olan hukuk kurallarının bilinmesi, uygulanması ve hukuk kurallarının bireyler tarafından anlamlandırılması son derece önemlidir. Temel düzeyde hukuk ve hukuka ilişkin kavramların bilinmesi olarak ifade edilen hukuk okuryazarlık kavramı, zaman içerisinde etkin vatandaş olmanın bir parçası olarak hukuk kurallarını anlama, uygulama, yorumlama ve bunları hayatın akışında uygun şekilde kullanabilme becerisine sahip olma şeklinde bir gelişim göstermiştir. Gerçekleştirilen bu çalışmada sosyal bilgiler alanında hukuk okuryazarlığına ilişkin gerçekleştirilen çalışmaların sistematik olarak incelenmesi amaçlanmaktadır. Bu amaç doğrultusunda 2018-2022 tarihleri arasında çeşitli veri tabanlarında yayınlanan makaleler ve lisansüstü çalışmalar incelenmiştir. Araştırmada çeşitli anahtar kelimeler ve filtreleme teknikleriyle 64 çalışmaya erişilmiştir. Dâhil edilme ve hariç tutulma kriterleri kapsamında, belirlenen kriterleri sağlamayan 54 çalışma inceleme dışı bırakılmıştır. Hariç bırakılan çalışmalar sonucunda 10 çalışma sistematik incelemeye alınmıştır. Araştırma kapsamında literatürde doğrudan sosyal bilgiler ve hukuk okuryazarlığı alanında gerçekleştirilen çalışma sayılarının oldukça az olduğu sonucuna ulaşılmıştır. Buna ek olarak gerçekleştirilen çalışmalarda ortaokul öğrencileriyle gerçekleştirilen çalışma sayısının sadece 1 olduğu sonucuna ulaşılmıştır.
Interstitial pregnancy
Authors:   Department of Gynecology and Obstetrics, Regional Hospital Trutnov, a.s., Czech Republic, Nesterová Anna , Boudová Barbora , Kestřánek Jan
Published: January 2023

Objective: A case report of a patient with interstitial pregnancy and a history of hyperprolactinemia. Case report: A 30-year-old woman was hospitalized for a suspicion of ectopic pregnancy and referred for laparoscopy. During the laparoscopic surgery, interstitial pregnancy was diagnosed and solved with cornuostomy. Conclusion: Ectopic interstitial pregnancy represents a serious worldwide issue because unrecognized, it can endanger a woman’s life, despite advances in ultrasound examination, the diagnosis often remains inaccurate. Laparoscopic surgical approach with evacuation of pregnancy with subsequent uterus suture represents one of the possible approaches. This method is minimally invasive and safe. Key words: interstitial pregnancy – laparoscopy – methotrexate
Selected pathological conditions affecting endometrial receptivity
Authors:   Department of Obstetrics and Gynecology, Medical Faculty of Masaryk University and University Hospital Brno, Czech Republic, Mekiňová Lenka , Ješeta Michal , Crha Igor , Crha Karel , Vodička Jan , Hudeček Robert , Remundová Kateřina , Matušková Eva , Pilka Radovan
Published: January 2023

Objective: A summary of new knowledge on embryo implantation in dependence on quality of the endometrium. Methods: Literature review from August 2022 of the relevant publications in Web of Science, Scopus and PubMed/Medline databases, focused on “endometrial receptivity”, “polycystic ovary syndrome”, “endometriosis”, “SARS-CoV-2”. Results: The receptive state of the endometrium is a result of physiological remodeling and immune system activity modulated by the microbiome. This balance can be disturbed by myomas, polyps, sactosalpings, adenomyosis, endometriosis, polycystic ovary syndrome, infections. The effect of SARS-CoV-2 infection is being discussed. For a successful implantation, timing of transfer is crucial. The ultrasound examination is used conventionally. In specific cases, hysteroscopy and endometrium bio psy are recommended. Histological and immunohistochemical evaluation is performed together with examination of microbiome or transcriptome. To support the implantation, gestagenes are used, or metformin in the patients with polycystic ovary syndrome. In cases of a repeated implantation failure, the intrauterine infusion of mononuclear cells or platelet rich plasma is used, subcutaneous application of granulocyte colony stimulating growth factor, intravenous application of atosiban or intrauterine application of human chorionic gonadotropin. Conclusion: Recent research in the field of transcriptomics, proteomics and reproductive immunology uncovers the process of implantation more deeply and opens a new stage of the assisted reproduction. Key words: receptivity of endometrium – implantation – SARS-CoV-2 – endometriosis – polycystic ovaries – adenomyosis – proteome – secretome
PERAN PEMANFAATAN DANA BAGI HASIL CUKAI HASIL TEMBAKAU DALAM MENCAPAI TUJUAN PENGENAAN CUKAI
Authors: Samuel Samuel
Published: January 2023

Cukai hasil tembakau memberikan sumbangsih yang signifikan dalam APBN setiap tahunnya. Kenaikan tarif cukai hasil tembakau tiap tahun dan pemanfaatan dana bagi hasil cukai hasil tembakau sesuai dengan tujuan yang diamanatkan oleh Undang-Undang yang mengatur tentang Cukai serta RPJMN 2020-2024 yaitu untuk menekan konsumsi rokok di Indonesia sekaligus untuk mengoptimalkan penerimaan negara. Hal ini dikarenakan banyaknya eksternalitas negatif yang dihasilkan. Upaya pemerintah untuk menekan tingkat konsumsi rokok ternyata tidak berbanding lurus dengan tingkat konsumsi rokok yang cenderung stabil tiap tahunnya. Pemanfaatan dana bagi hasil cukai yang masih jauh dari tujuan untuk menekan konsumsi rokok alih-alih justru bertujuan untuk meningkatkan industri hasil tembakau. Bercermin dari tiga negara penghasil tembakau terbesar di dunia yakni Cina, India dan Brasil, dibutuhkan upaya pemerintah yang serius untuk menekan tingkat konsumsi rokok di Indonesia yakni dengan pemanfaatan dana bagi hasil cukai hasil tembakau yang mengarah untuk berkurangnya industri hasil tembakau.

 

Tobacco excise contributes a large amount to the state budget each year. The annual rise in tobacco excise rates and the utilization of tobacco revenue-sharing funds (earmarking) are in line with the objectives set out in the Excise Law and the 2020-2024 RPJMN, namely to reduce cigarette usage in Indonesia while also maximizing state revenues. Because of the enormous number of negative externalities generated, this is the case. The government’s efforts to reduce cigarette consumption are not directly related to cigarette consumption, which is fairly stable year after year. The utilization of excise revenue-sharing money is not intended to reduce cigarette consumption; rather, it is itended to improve the tobacco products sector. In light of the world’s three largest tobacco-producing countries, China, India, and Brazil, serious government efforts are required to reduce cigarette consumption in Indonesia, namely through the use of tobacco excise revenue-sharing funds that result in a reduction in the tobacco products industry.
Selman YILMAZ, Türkiye de Toplumsal ve Dini Değişimin İzleri: Ak Parti İktidarında Nereden Nereye, Ankara: Grafiker Yayınları, 2019, 262 s., ISBN: 978-605-2233-62-7
Authors: Balamir Figen
Published: January 2023

Kritiğini yaptığımız bu kitap Ankara Üniversitesi’nde öğretim üyesi olan Selman Yılmaz’ın 2019 yılında tamamladığı çalışmasına aittir. Yazar, örneklem olarak belirlediği 420 öğretmen üzerinden Ak Parti iktidarının son on beş yılındaki toplumsal değişimin analizini yapmaktadır. Kitapta “Türk halkı gerçekten dindarlaşmış mıdır? Yoksa dinden uzaklaşmış mıdır? “Çevre”deki halk “merkez”leşmeye mi başlamıştır?” gibi birçok soru Milli Eğitim Bakanlığı’na bağlı kurumlarda çalışan öğretmen profilindeki değişim aracılığıyla yanıtlanmaktadır. Uzun soluklu bir araştırmanın ürünü olan kitapta bulunan zengin içerik, din ve toplumsal değişim arasındaki ilişkiyi somutlaştırıcı bulgular eşliğinde okuyucular için “hafıza tazelenmesi” de sağlamaktadır.
Kur an Bağlamında Milli Kimlik ve Dil
Authors: Sadan Hamza
Published: January 2023

Bu çalışmada milli kimlik ve dil konusu ayetler bağlamında ele alınmıştır. Kur’an’a
göre, farklı milliyetler ve diller Hz. Âdem kaynaklı olarak Allah Teâlâ tarafından var
edilmiştir ve Allah Teâlâ’nın kudretinin delillerindendir. Dolayısıyla Kur’an’da milli
kimliği oluşturan farklı unsurlar birer üstünlük ve savaş vesilesi değil tanışma ve
kaynaşma nedeni olarak zikredilmiştir. Konuyla ilgili olarak üç ayet bulunmaktadır.
Bu ayetler Bakara suresinin 31, Rûm suresinin 22 ve Hucurât suresinin 13.
ayetleridir. İlgili ayetlerin ilkinde isimleri Hz. Âdem’e Allah Teâlâ’nın öğrettiği,
ikincisinde dillerin ve renklerin Allah’ın birer ayeti olduğu, üçüncüsünde ise
insanların bir erkek ve dişiden yaratıldığı ve bir biriyle tanışmaları için çeşitli kavim
ve kabilelere ayrıldığından bahsedilmektedir. Ayetlerin yorumları verilirken daha
çok Türk dünyasının yetiştirmiş olduğu bazı müfessirlerin görüşlerinden
yararlanılmıştır. Bunlardan biri erken dönem müfessirlerinden Maturidî (ö. 303),
diğeri sonraki dönem müfessirlerinden Zemahşerî (ö. 538) ve üçüncüsü de çağdaş
dönem müfessirlerinden Elmalılı Hamdi Yazır (ö. 1942)’dır. Türk kimliğini taşıyan
bu önemli müfessirlerin ilgili ayetler hakkındaki bakış açıları yansıtılmaya
çalışılmıştır.
Tevessül, İstiğâse ve Teberrüke Dair İki Farklı Paradigmanın Analizi -Ehl-i Sünnet Sûfî Gelenek ve Selefî Yaklaşım-
Authors: Tığlıoğlu Mehmed Zahid
Published: January 2023

Geleneksel sûfî anlayış ile Selefî anlayış arasındaki ihtilafların başında tevessül,
istiğâse ve teberrük konuları gelmektedir. Sûfî anlayışta tevessül, istiğâse ve
teberrük daha geniş bir zemine otururken, Selefî yaklaşımda bu konular daha dar
kapsamda değerlendirilmiştir. Kendisiyle tevessül, istiğâse ve teberrük edilen zâtın
hayatta olması ya da olmaması arasında Sûfîlere göre fark yok iken, Selefîlere göre
fark vardır ve bu onlara göre doğrudan tevhidle ilgili olan çok önemli bir konudur.
Selefîlere göre hayatta olan şahıslarla tevessül, istiğase ve teberrükte bulunmakta
bir beis yokken, ölmüş kişilerle tevessül, istiğâse ve teberrükte bulunmak şirk
olarak değerlendirilmektedir.
Ekberiyye Geleneği âlim ve âriflerinden olan sûfî, fakih Abdülgani en-Nâblusî’nin (ö.
1143/1731) de içinde bulunduğu Ehl-i Sünnet sûfî âlimlere göre konu Allah’ın
kudreti, iradesi ve te’siri çerçevesinde değerlendirilmektedir. Burada, birbiriyle
tezat teşkil eden iki farklı paradigma karşımıza çıkmaktadır. Bu dikkat çekici ve
incelemeye değer bir husustur. Biz makalemizde bu iki paradigmayı, konu hakkında
görüşlerini ve tevessül, istiğâse ve teberrük konularını hangi zeminde
değerlendirdiğini tahlil edeceğiz. Ehl-i Sünnet sûfîlerin yaklaşımını Selefî yaklaşımla
mukayese edeceğiz. Makalemizde araştırma tekniklerinden analitik ve
karşılaştırmalı metot kullanılmıştır.
Nizâr Kabbânî ve Cemal Süreya nın Şiirlerinde Kadın İmgesinin Karşılaştırılması
Authors: Mısır Fatma Zehra
Published: January 2023

Edebiyat alanında karşılaştırma yapmak akademik çalışmaların verimliliğini
arttırmaktadır. Özellikle son zamanlarda Karşılaştırmalı Edebiyat, araştırmacılar
nezdinde çok kullanılan ve yaptıkları çalışmalara yeni bir soluk getiren kavram
haline gelmiştir. İki yazarın, iki şairin ya da iki eserin Karşılaştırmalı Edebiyat
bağlamında incelenip yeni bir çalışma haline getirilmesi, araştırmacılara ve
okuyuculara farklı bir bakış açısı kazandırmıştır. Bundan dolayı bu çalışmada, farklı
kültür ve çevrede yetişmiş ama aynı yıllarda yaşamış olan iki akran şairin şiirleri
Karşılaştırmalı Edebiyat bağlamında incelenmiştir. Genel olarak şiirlerinde kadın
imgesini nasıl işlediklerine dair bilgilere karşılaştırma yapılarak yer verilmiştir.
Çalışmada ilk olarak edebiyat alanı içerisinde kullanımı son yıllarda yaygın olan
‘’Karşılaştırmalı Edebiyat’’ hakkında geniş bilgiler verilmiştir. Daha sonra ele alınan
şairlerin hayatları ve kaleme aldıkları eserler ayrıntılı bir şekilde anlatılmıştır.
Ayrıca söz konusu şairlerin kadın imgesini içeren şiirleri başlıklar halinde ele
alınmış ve bu şiirler karşılaştırma yapılarak incelenmiştir. Çalışmadan elde edilen
verilere sonuç bölümünde yer verilmiş ve çalışma kaynakça bölümüyle
desteklenmiştir
Büveyhîler Dönemi İlim ve Tıp Merkezlerinin Gelişiminde Vakıfların Rolü ve Âkıbetleri
Authors: Uç Muhammed
Published: January 2023

Hicrî dördüncü yüzyılda İran coğrafyasının batı yakasında Büveyhîler’in yönetiminin istikrâr bulmasıyla
birlikte sosyal ve kentsel kurumlar desteklendi. Bu sosyal kurumlar, tıp ve eğitim hizmetleri sunmak için
esasında ilim merkezleri (Dâru’l-İlmler ve Kütüphaneler) ve hastaneler şeklindedir ve şehirlerde kurulan
vakıflara dayanarak oluşturulmuşlardır. Bu araştırma ise, söz konusu kurumların teşekkülünde ve
devamlılığında vakıfların oynadığı rolü mütalaa ederken, Büveyhîler dönemi vakıflarının yükselişlerini veya
düşüşlerini etkileyen faktörleri tarihsel gelişmeler çerçevesinde incelemeye ve keşfetmeye çalışmaktadır.
Elimize ulaşan sonuçlar, Büveyhîler dönemi kurumları ve onların vakıflarının istikrarlı bir mâlî kaynak
sağladığını, aynı zaman diliminde onların ilerleme kaydedebilmeleri için gerekli zemini oluşturduğunu
göstermektedir. Ne var ki, Büveyhîler’in siyasî egemenliğinin nihayete ermesinden sonra dâru’l-ilmler,
kütüphaneler ve onlara bağlı olan vakıflar Şiî eğilimleri bahanesiyle tarihî hadiseler sırasında zarar
görmüştür. Bunun sonucunda ise faaliyetleri azalmıştır. Ancak hastanelerle ilgili vakıflar İlhanlılar’ın son
dönemlerine kadar varlıklarını sürdürmüştür. Fars Atabeyleri gibi yarı bağımsız ve mahallî yönetimler,
Büveyhîler’in bazı şehirlerde kurdukları tıp vakıflarının varlıklarını sürdürmesine yardımcı olmuştur.
Bağımsızlık Sonrası Özbekistan da Yayımlanan Özbekçe Meal ve Tefsir Çalışmaları
Authors: Fergani Hacı Ekber
Published: January 2023

İslam’ın temel kaynağı olan Kur’an-ı Kerim üzerinde zaman, mekân ve insanların durum ve ihtiyacına göre çok sayıda tefsir yazıldı ve hala yazılmaya devam etmektedir. Bu kutsi işi omuzuna alan ve bu alanda etkili ve yön verici özelliğe sahip olan müfessirlerin bir kısmı Mâverâünnehir bölgesinde (Amuderya (Ceyhun) ile Sırderya (Seyhun) arası) yetişmiştir. Bu bölgede Arapça tefsirler dışında meskûn halkın konuştuğu Farsça ve Türkçe meal ve tefsirler telif edilmiştir. Sovyetler döneminde Kur’an çalışmalarında bölge dışındaki faaliyetleri hesaba katmazsak bir duraklama söz konusudur. Bağımsızlık sonrası ise Özbekistan’da meal ve tefsir çalışmalarının yeniden canlandığını söyleyebiliriz. Bu çalışmada bağımsızlık sonrası Kur’an-ı Kerim’in Özbekçe mealler ve tefsirlerin tanıtımı yapılacaktır. Bu bağlamda sekiz Özbekçe meal ve yedi tam ve kısmi tefsir tanıtılmaktadır. Araştırmada literatürün tasnifi, tanıtımı, genel değerlendirmeleri yapılacaktır. Onların metot ve muhteva yönlerine kısaca işaret edilecektir. Konuya hazırlık mahiyetinde bağımsızlık öncesi bu alandaki çalışmalara göz atılacaktır. Ayrıca bu alanda yapılacak çalışmalara yol ve yön gösterme istidatları değerlendirilecektir.
Computed tomography independent quantitative determinants of CAD-RADS 4 versus CAD-RADS 3 for calcified coronary lesions
Authors: Sakrana Amal Abdelsattar , Abou El Atta Heba M. , Mohammad Goda , Bayoumi Dalia
Published: January 2023

Introduction

An investigation of coronary computed tomography angiography (CCTA)-derived quantitative parameters to determine CAD-RADS 4 versus CAD-RADS 3 of coronary lesions with moderate to severe calcification.

Material and methods

The study included 150 coronary lesions proven to have moderate or severe stenosis by invasive coronary angiography and showing moderate to severe calcification in CCTA. Various CCTA-quantitative parameters were correlated to the degree of stenosis (moderately versus severely stenosed lesions). Their sensitivity and specificity to detect severe stenosis (supposed to be corresponding to CAD-RADS 4) were examined at multiple cut-off points.

Results

The calcification remodelling index (CRI) was the only statistically significant independent computed tomo­graphy angiography-derived predictor of severe stenosis versus moderate stenosis on multivariate regression analysis. The best cut-off value was ≤ 0.84, with 77.78% sensitivity and 86.46% specificity.

Conclusions

From all quantitative-derived CCTA parameters, CRI ≤ 0.84 was the predictor with the highest diagnostic performance for severe versus moderate stenosis in moderately to severely calcified coronary lesions. Accordingly, CRI can help to determine CAD-RADS 4 versus CAD-RADS 3.
Single-centre experience in the endovascular treatment of acute superior mesenteric artery occlusion: an observational analytical 3-year study
Authors: Kaupas Dominykas , Matusevičiūtė Ramona , Kaupas Rytis Stasys
Published: January 2023

Introduction

To retrospectively evaluate single-centre experience in endovascular therapy (EVT) of acute superior mesenteric artery (SMA) occlusion by assessing technical success, mortality, and its dependence on the level and aetiology of occlusion.

Material and methods

Eighty patients presented with acute SMA occlusion and underwent EVT at our centre from 2018 to 2020. Clinical diagnosis was confirmed by computed tomography angiography (CTA). Based on findings of CTA and digital subtraction angiography, we classified all cases by the number of SMA large branches that remained non-occluded (ostial, proximal, distal occlusion), as well as according to aetiology (embolic, thrombotic). Technical success was evaluated according to restoration of blood flow to the SMA stem and all large branches (successful, partially successful, failure).

Results

Thrombotic aetiology was identified in 25.0% and embolic in 75.0% of patients. We distinguished 3 occlusion level types: ostial occlusion (23.8%), proximal occlusion (47.5%), and distal occlusion (28.7%). 67.5% of cases were technically successful, 12.5% were partially successful, and 20.0% resulted in technical failure. The 30-day mortality rate was 55.0%. EVT technical success did not statistically depend on the aetiology or on the level of occlusion. The aetiology of occlusion had no statistical significance regarding intrahospital mortality. In the group with EVT failure, fewer non-occluded large branches meant more fatal cases, and vice versa.

Conclusions

Despite EVT technical success rates being adequate, mortality rates remain extremely high. While the occlusion level appeared to have no influence over EVT technical success rates, it may be a potentially useful prognostic factor in the case of failed recanalization. Aetiology of the occlusion seemed to have no impact on technical success or mortality.
Transradial versus transfemoral arterial access in the uterine artery embolization of fibroids
Authors: Ghosh Abheek , Agnihotri Tanvir , Gupta Vikash , Sitwala Palak , Stanley Monica , Cai Stephen , Akhter Nabeel Mohsin
Published: January 2023

Introduction

Transradial arterial access has become more popular in body interventional procedures but has not been ubiquitously adapted. This retrospective study assesses the efficacy of this approach in uterine artery embolization. Aim of the study was to compare transradial to transfemoral arterial access in patients undergoing uterine artery embolization for the treatment of fibroids.

Material and methods

A total of 172 patients underwent uterine artery embolization procedures at our institute from October 2014 to June 2020. Of these, 76 patients had their operations performed via transfemoral access while 96 underwent transradial access. The peak radiation dose, fluoroscopy time, procedure time, total contrast volume, and equipment cost for each procedure were all reviewed to evaluate for statistical differences between the 2 groups.

Results

All cases were technically successful without major complications. The average peak skin dose was 2281 mGy, with no statistical difference between the transradial or transfemoral cohorts. Average fluoroscopy time was 25 minutes, also with no statistical difference between the subsets. Mean procedure time was 100 min, and mean contrast volume usage was 138 mL with no statistical differences. Similarly, the average equipment cost was $2204, with no significant differences found between transradial and transfemoral access.

Conclusions

With respect to many pertinent radiation parameters, transradial access was evaluated as being an equally efficacious alternative to transfemoral access in uterine artery embolization procedures. The results of this study suggest that transradial access should be considered more often, whenever viable, as an option in the uterine artery embolization treatment of fibroids.
Efficacy of green synthesized gold nanoparticles conjugated with 5-fluorouracil in targeting breast cancer cell - An in vitro study
Authors: Chokkalingam Priya , P.K.P. Sobha , Krishana V.S. Swathi , Safeen C. Wajiha , Hari Rajeswary , Kumar G. Mohan , P. Balashanmugam
Published: January 2023

Introduction and Aim: Presently, research and development in nanomaterials is gaining hypersonic reach in various areas of applications.  Biological way of preparing such nanomaterials is acquiring noteworthiness in the view of affordability and environment-friendly approach. In this current work, gold nanoparticles(AuNPs) were prepared using leaves extract of Chloroxylon swietenia having anticancer behaviour with the focus to blend the therapeutic activity among the nanoparticles was studied by conjugating with 5 Fluorouracil (5-FU) to target breast cancer cells.
 
Materials and Methods: Chloroxylon swietenia leaf extract was prepared and chloroauric acid (HAuCl4) was added to synthesis AuNPs. As prepared AuNPs were characterized using UV-visible spectrophotometry, TEM and EDAX. The antioxidant tests were done by DPPH assay. Further, the AuNPs were conjugated with5-fluorouracil. The in vitro cytotoxicity of the synthesized gold nanoparticles and conjugated AuNPs were assessed by MTT assay against normal and A549 breast cancer cell lines and the efficacy was noted.
 
Results: Preparation of AuNPsthrough the leaf extract of C. swietenia was carried out in an effective way.The preliminary test for the confirmation of as synthesized NPs was done through spectroscopic analysis, resulting in a characteristic peak at 539nm. The TEM examination provided the information about size and the pattern of NPs. Cytotoxicity investigation of NPs with VERO cell lines confirmed its non-toxic nature towards the cells. Anticancer study with A549 breast cancer cell lines also proved the NPs with IC50 value at 25µl/ml. 
 
Conclusion: The conjugated AuNPs with 5-FU revealed anticancer activity in A549 breast cancer cell line but correspondingly it is proved to be safe with standard VERO cell line. The findings stand with a strong point to expand the studies through the evolution of potential drug molecules to deal with the disease of interest.
Effect of exercise, relaxation, and ergonomics on physiological stress indicators - An experimental study on teachers
Authors: G. Vaishnavi , M. Majitha Parveen , Nathan C.V. Senthil , G. Tharani , K. Kamatchi , G. Rajalakshmi , G. Yuvarani , D. Aruna
Published: January 2023

Introduction and Aim: Stress is a reaction of the body to substantial or unusual demands. It, a complex reaction of the neurologic and endocrinologic system which can initiate the ‘Fight or Flight’ response. This may lead to headache, tense muscles, insomnia. Stress can alter the memory function, immune function, metabolism, and susceptibility to the disease. The effect of stress and relationship in making teachers quite inefficient in their profession is a growing concern. The present study objective is to investigate the effective significance of exercise, relaxation, and ergonomics on physiological stress in teachers.
 
Materials and Methods: A total of 30 teachers, both male and female were randomly selected. They supported the inclusion and exclusion criteria and were between 30 to 60 years, separated into 2 groups. They were asked to fill necessary information in the stress profile for teachers. The subjects with moderate to high stress were taken for the study and were divided into two groups. Group ‘A’ were given aerobic stepper exercise and relaxation techniques. Group ‘B’ were given aerobic stepper exercise and suggestions given on ergonomic correction for an intervention period of about 8 weeks, 5 days per week 45 minutes per session. Pre- and post-test values were taken on blood pressure and blood glucose level using sphygmomanometer and glucometer.
 
Results: The pre- and post-test between group A and group B show a highly significant difference. However, group A showed higher significance than group B.
 
 
Conclusion: According to the findings, aerobic stepper exercise with relaxation techniques shows highly significant difference and aerobic stepper exercise with ergonomic correction shows significance but aerobic exercise with relaxation technique is highly effective in reducing stress and maintaining blood pressure and glucose level in teachers.
Serum fatty acid transport protein 1 in women with and without breast cancer
Authors: Acharya Ranjitha , S. Shetty Shilpa , Monteiro Flama , S. Shetty Abhijith , Shetty D. Prashanth , Patil Prakash , Kumari N. Suchetha
Published: January 2023

Introduction and Aim: Obesity influences the serum lipid profiles leading to dysregulation of lipid metabolism in which fatty acid transporter like FATP 1 (Fatty acid transport protein 1) are recognized to play a key role in BC progression. Aim of the present study is to compare FATP1 levels in women with and without BC.
 
Materials and Methods:  In this case-control study, 50 BC and 50 control subjects were recruited. Serum was separated from the blood and baseline characteristics like height, weight, age and BMI were noted for all the subjects. Lipid profile and serum level of FATP1 was estimated using a commercially available kit. P<0.05 was found as statistically significant.
 
Results: The serum FATP1 levels in subjects with breast cancer differed significantly between the case and control. TC, TAG, HDL-C, LDL-C, and VLDL-C differed between two groups and were statistically significant. Further, serum FATP1 levels in subjects with BC were compared based on the status of the receptor showed a significant difference in TG, VLDL-C and serum FATP1.Correlating the serum FATP1 levels with baseline characteristics and lipid profiles in subjects with BC, age showed a positive correlation with serum FATP1 levels. Correlation of FATP1 with different receptor status in subjects with BC showed a positive correlation between FATP1 and VLDL in ER+/PR-/HER2+ receptor status, FATP1 and HDL-C showed a positive correlation in triple-negative BC.
 
Conclusion: Though extensive research on breast cancer is underway, Study reports on serum level of FATP1 in BC are scarce. Current study demonstrates the importance of serum levels of FATP1 in BC. Further study on the molecular regulation of FATP1 in BC will add to the knowledge, and findings of the study implicates for utilizing FATP1 as a biomarker in BC.
Is early onset androgenetic alopecia related to hyperuricemia? A case control study
Authors: Ghoshal Loknath , Biswas Rabindranath , Sarkar Dibyajyoti
Published: January 2023

Introduction and Aim: Early onset androgenetic alopecia (AGA) ensues before age of 35 years and develops stage 3 in Hamilton-Norwood classification. AGA is more noticeable in males. Early onset AGA has been linked to hyperuricemia (a metabolic disorder characterised by elevated levels of serum uric acid) but has been explored inadequately. Hyperuricemia (HU) corroborates with the presence of hypertension, obesity, type 2 diabetes mellitus, metabolic syndrome and chronic kidney disease (CKD). Given the above and lack of data in this context, a study in this regard was necessary. This study was intended to relate the prevalence of HU and level of serum uric acid (SUA) levels in patients of early onset AGA versus matched controls and determine correlation between the severity of alopecia and serum uric acid and between the SUA and age (secondary objectives).
Materials and Methods: Each patient was evaluated by taking history, clinical examination and laboratory investigation.
Results: The groups were not different from each other with respect to age (p=0.5). The SUA in the AGA patient group was greater than in the control group; however the difference was not statistically significant. (p=0.2). AGA patients were found to have higher number of hyperuricemics as compared to the control group (Chi square test P=0.03, Odds ratio=0.39). There was no correlation between the severity of alopecia or the age of the subject with SUA.
Conclusion: Our study found that men who have early onset AGA tend to have higher serum uric acid levels; also, hyperuricemics are commoner in patients who have early onset AGA than in controls.
Association between genetic variants in ANGPTL4 (T266M) and MC4R genes predisposing to obesity
Authors: Adel Abbas Zainab
Published: January 2023

Introduction and Aim: Recently, obesity has begun to be seen not only as a physical state of an individual but also as an illness in and of itself. It is possible that there is not much research done on the exact variants or genes that put people at risk for obesity in Iraq. The aim was to sight the genetic variants predisposing to obesity in Baghdad population by screening the associated ANGPTL-4 and MC4R genes.
 
Materials and Methods: A total of 124 individuals aged between 15-67 years participated in this study that was prospective, descriptive, and cross-sectional in nature. Blood collected from each individual was analyzed for biochemical parameters such as fasting blood glucose, random blood glucose, HbA1c, thyroid function tests (TSH) and complete blood count. Genomic DNA was subjected to amplification of the ANGPTL4 gene. The amplified product was subjected to restriction digestion using the enzyme NlaIII and further genotyped.
  
Results: This study found no correlation between ANGPTL-4 (T266M) and MC4R rs13447324 among obese population studied in Baghdad, Iraq.
 
Conclusion: The study found no conclusive evidence linking the ANGPTL-4 T266M gene to obesity in the Baghdad population. The study also discovered that people of Baghdad did not have an association between MC4R rs13447324 and obesity. However, larger sample size investigations are required.
Study on the effect of Chamomile extract on melatonin hormone levels in subjects suffering from insomnia and anxiety
Authors: M. Hasan Sulaiman
Published: January 2023

Introduction and Aim: Insomnia and anxiety are the most common among the psychiatric disorders. These disorders have been associated to melatonin levels; an endocrine hormone produced by the pineal gland in brain. Melatonin has also been associated to several metabolic processes in the body. In this study we aimed to investigate into the effect of chamomile extract on serum melatonin levels as well as on various other blood parameters.
 
Materials and Methods: Fifty randomized subjects were orally treated with chamomile extract (15% w/v daily) for 8 weeks. Liver enzymes, urea, creatinine, and lipid profile were measured to see the effect of chamomile extract on the body.
 
Results: From the results, we found a significant increase in the melatonin levels after treatment with chamomile extract. We also did not observe any rise in the liver enzyme levels, blood urea and serum creatinine. Also we found decrease in cholesterol and triglyceride levels.
 
Conclusion: This study suggests that chamomile extract can be a natural and safe nutritional strategy for improving sleep duration and quality and in improving the lipids levels.
Role of ratios of neutrophil and monocyte to lymphocyte and red cell distribution width to platelet in the detection of early onset neonatal sepsis in comparison with serum C-reactive protein
Authors: Agarwal Tanvi , Hanaganahalli Basavaiah Sridevi , Kudurugundi Basavaraju Vatsala , Rao A. R. Sneha
Published: January 2023

Introduction and Aim: Early onset neonatal sepsis (EONS) is a preventable cause of neonatal mortality and morbidity. Blood culture, the current gold standard has a turn-around time of 48 to 72 hours and high false negatives. Thus, there is a need for reliable biomarkers for its early detection. The present study aims to find the utility of ratios derived from components of complete blood count in detecting EONS.
 
Materials and Methods: The laboratory investigations of neonates with and without clinical sepsis were recorded using purposive convenience sampling technique. The total leucocyte count, absolute neutrophil count, C-reactive protein (CRP) and ratios of blood counts were compared by Mann Whitney test. Their performance was then analysed by receiver operating characteristic analysis.
 
Results: A total of 196 neonates aged 0 to 3 days were considered for the study, out of which 98 cases were study group. Serum CRP and red cell distribution width to platelet (RPR) ratios were found to have statistical significance, albeit low sensitivity and specificity in detection of EONS. Positive correlation of RPR was found with CRP (p value=0.001). The area under the curve for CRP and RPR was 0.661 and 0.628 respectively. However, there was no statistical significant difference in neutrophil and monocyte to lymphocyte ratios between the study and comparative groups.
 
Conclusion: In the background of low yield of culture positivity and its longer turnaround time, RPR can be used as a reliable biomarker in the diagnosis of EONS in conjunction with CRP.
Use of spatial analytics and geographic information systems in childhood diarrhoea in rural areas of India: A protocol paper
Authors: Mackwin Kenwood Dmello , Badiger Sanjeev , Kumar Sudeep , N. Kumar , N. D’Souza , J. Purushotam
Published: January 2023

Introduction and Aim: The most recent advancement in epidemiology is using Geographic Information Systems (GIS) to comprehend illness based on clustering and spatial analysis. Using spatial analysis has shown positive changes in sanitation, reducing diarrhoea's burden. This study put forwards the methodology used to analyze spatiotemporal clustering and hotspot areas of childhood diarrhea in Karkala taluk, Udupi during 2015 to 2018.
 
Materials and Methods: This study describes the methods used to analyze the space-time clustering and local indicators of spatial association (LISA) of childhood diarrhoea using the GeoDa and SaTScan programmes. At the Karkala taluk, data on under-five diarrhoea was gathered throughout time and space to develop the geospatial models. While the timing of the onset of the diarrhoea impacts the temporal characteristics, the child's position at the time of the event determines the spatial characteristics. The child's location and time of diarrheal episode was considered for the geospatial analysis.
 
Results: The Kulldorff scan statistic (SaTScan v10.1) was employed for geographical analysis, and GeoDa software used for LISA and hotspot analysis. The randomness distribution of childhood diarrhoea over time and space was determined using the Kulldorff scan statistic software. The SaTScan locates and evaluates the statistical significance of geographical clusters based on the number of cases inside and outside the cylinder window. The scanning window in the software uses a cylinder with an elliptical or circular base to study intervals for time, space, and space-time. The different combinations of High and Low categories of the spatial association are covered by the hotspot analysis utilizing the GeoDa software.
 
Conclusion: To build data-driven public health decision-making, it is required to link spatial and temporal patterns of diarrheal incidence among under-five children with predictive variables derived from routine data.
Formation of seedless berries in Codrianka grapes with the use of growth regulators
Authors:   Timiryazev Moscow Agriculture Academy, Panova Maria
Published: January 2023

The article presents the results of studying the influence of growth regulators on the formation of seedless berries in the grape variety of interspecific origin Codrianka. The size of berries of different types has been studied depending on the presence or absence of seeds in them. The preparations contributing to the formation of large seedless berries in the Codrianka variety have been identified. Keywords: GRAPES, GROWTH REGULATORS, SEEDLESSNESS, UVOLOGICAL ANALYSIS, SMALL DIAMETER BERRIES, PARTHENOCARPY
Theoretical foundations of resource potential management of the basic components of the agroecosystem
Authors:   Voronezh state agrarian University, Panin Evgeny , Vysotskaya Elena
Published: January 2023

The article discusses the main ways of managing the biological resource of the agroecosystem. The features of the functioning of its basic components, such as the plant component of agricultural production, soil, microorganisms, etc., are highlighted. It is noted that for the sustainability and realization of the bioresource potential, the agroecosystem must have: inertia and plasticity. The main basic component affecting the productivity of the agroecosystem is the soil. The possibilities of managing the bioresource potential of its components are limited by a number of biological and environmental conditions, the leading ones of which include agro-climatic, ecological, biological and technological components. Keywords: AGROECOSYSTEM MANAGEMENT, BIORESOURCE POTENTIAL, ECOLOGICAL IMPERATIVE, RESTYLING, ADAPTIVE APPROACH
Forensic Investigations of Propane-Related Food Truck Incidents
Authors: Schumacher John , Brown Charles , Jason Zachary , Shelp Dennis
Published: January 2023

The proliferation of propane-fueled food trucks and concession trailers over the last decade has led to a fast-growing industry. As with many nascent industries, accidents accompany the surge in growth, and the food truck industry is no exception. Numerous propane-related fires, flash fires, and explosions have resulted in property damage, business interruption, injury, and death. Conducting a proper investigation of a food truck incident is essential in determining the origin/cause and ultimately assigning liability and preventing recurrences. This paper discusses the food truck industry as well as the design, construction, and layout of the trucks. It provides an overview of the gas systems installed in the vehicles — from the cylinder or tank to the appliances, properties of propane, and relevant codes and standards applicable to food trucks that utilize propane. Finally, an outline of the proper methodology to use when investigating a food truck incident is pro-vided, and a food truck explosion case study is presented.
Failure Analysis of Cylinder Used In a Car Flipper Device
Authors: Khan Faisal , Gafoor Altaf
Published: January 2023

A car flipping device is a special effects aid used to flip cars in the production of movies and television shows. The device uses a pivoting arm that moves under the stroke of a cylinder powered by compressed ni-trogen. In a trial run of the device, the cylinder’s piston broke through the cylinder cap. A kinematic analysis developed a parametric mathematical model of the motion of the cylinder arm and piston, which formed the basis for a finite difference analysis to determine the speed of the cylinder’s piston at the end of its stroke. Metallurgical testing was conducted on the broken cylinder to determine the stress-strain characteristics, im-pact resistance, and Scanning Electron Microscopy (SEM) used to examine the fracture surface. The analysis determined that the kinetic energy of the piston was adequate to cause yielding of the cylinder but not rupture. Continued usage degraded the impact resistance available until rupture occurred.
FE Investigation into Manufacturing- and Design-Related Issues Contributing to the Failure of a Climbing Treestand
Authors: Rasty Jahan , Parker Olin , Mills Mathew
Published: January 2023

The foot platform of a climbing treestand fractured while a user was standing on it in the process of secur-ing his harness to a tree. Analysis of the frame’s fracture surface revealed a manufacturing defect in the form of a ¼-inch diameter hole next to the fracture area, likely created during the welding process. To prove that this defect was the proximate cause of the treestand’s failure (under reasonably expected and foreseeable use conditions), a series of tests on exemplar treestands as well as finite element analysis were performed. It was concluded that the defect reduced the fracture toughness of the treestand by 40%. In addition, it was found that the manufacturer failed to account for additional stress caused by dynamic loading experienced during normal use. The authors opined that both the reduced strength and the omission of dynamic loading in the de-sign resulted in the treestand’s frame failure. Appropriateness of the manufacturer’s reliance on users always wearing their full body harness is also discussed. This paper examines the contribution of the drilled hole to the integrity and suitability of the ASTM-required Factor of Safety (FOS) of 2.
Evaluasi Dampak Pelatihan Teknis Agribisnis Sayuran Pola On-Site Training Model (OTM) Terhadap Pendapatan Petani Brokoli
Authors: Rosdiantini Rosros , Suryaningrum Dewi Padmisari
Published: January 2023

Pelatihan Agribisnis Sayuran merupakan salah satu kegiatan pelatihan yang dengan menggunakan pola On Site Training Model (OTM)  mempunyai tujuan untuk meningkatkan pengetahuan, keterampilan, dan  sikap, yang pada akhirnya dapat meningkatkan pendapatan petani. Pelaksanaan suatu proses pelatihan  memerlukan evaluasi untuk menunjukkan apakah tujuan telah tercapai atau belum. Tujuan penelitian ini untuk (1) menentukan besarnya pendapatan dan R/C usahatani brokoli sebelum dan setelah mengikuti kegiatan pelatihan, (2) menganalisis pendapatan usahatani bokoli antara usahatani yang dilakukan sebelum dan setelah mengikuti kegiatan pelatihan, (3) menganalisis R/C usahatani bokoli antara usahatani yang dilakukan sebelum dan setelah mengikuti kegiatan pelatihan. Penelitian ini mengunakan metode deskriptif, dengan responden sebanyak 30 orang petani yang mengikuti pelatihan. Analisis yang digunakan yaitu analisis pendapatan usahatani dan uji beda perbandingan menggunakan uji t sampel berpasangan (paired sample). Hasil menunjukan bahwa (1) rata-rata pendapatan usahatani brokoli di Desa Kayuambon Kecamatan Lembang sebelum mengikuti kegiatan pelatihan yaitu sebesar Rp. 3.792.783 dan setelah mengikuti kegiatan pelatihan sebesar Rp. 5.565.083. (2) pendapatan petani setelah mengikuti pelatihan lebih besar dan berbeda nyata daripada pendapatan sebelum mengikuti pelatihan (3) nilai R/C setelah mengikuti pelatihan lebih besar dan berbeda nyata daripada nilai R/C sebelum mengikuti pelatihan.