bluuebunny/crossref_metadata_2025 huggingface dataset:
Biology of Peptide Transporter 2 in Mammals: New Insights into Its Function, Structure and Regulation
Authors: Wang Caihong , Chu Chu , Ji Xiang , Luo Guoliang , Xu Chunling , He Houhong , Yao Jianbiao , Wu Jian , Hu Jiangning , Jin Yuanxiang
Published: September 2022

Peptide transporter 2 (PepT2) in mammals plays essential roles in the reabsorption and conservation of peptide-bound amino acids in the kidney and in maintaining neuropeptide homeostasis in the brain. It is also of significant medical and pharmacological significance in the absorption and disposing of peptide-like drugs, including angiotensin-converting enzyme inhibitors, β-lactam antibiotics and antiviral prodrugs. Understanding the structure, function and regulation of PepT2 is of emerging interest in nutrition, medical and pharmacological research. In this review, we provide a comprehensive overview of the structure, substrate preferences and localization of PepT2 in mammals. As PepT2 is expressed in various organs, its function in the liver, kidney, brain, heart, lung and mammary gland has also been addressed. Finally, the regulatory factors that affect the expression and function of PepT2, such as transcriptional activation and posttranslational modification, are also discussed.
Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization
Authors: Yu Yang , Zhao Yuzhen , Mi Yongsheng , Zhao Yang , Guo Zhun , Zhang Huimin , Wang Dong , Miao Zongcheng
Published: September 2022

A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives. The structure of each sample was characterized by Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), Fourier transform infrared (FTIR) and elemental analysis. The characterization of the products by Ultraviolet-visible (UV-vis) and Photoluminescence (PL) spectroscopy proves that the addition of click groups has an important effect on the optoelectronic properties of pyrene derivatives. The Z-scan technique was used to test the third-order nonlinear optical (NLO) properties of the samples, and it could be found that the NLO properties of the products were improved and the transition of saturable absorption and reverse saturable absorption occurred with the addition of click reagent. These factors indicate that the click-modified pyrene derivatives have potential applications in areas such as optical limiting.
A New Correction Theory and Verification on the Reducing Rate Distribution for Seamless Tube Stretch-Reducing Process
Authors: Hu Jianhua , Yang Sheng , Huang Yulong , Wang Xiaohua , Chen Jianxun
Published: September 2022

The reducing rate distribution is critical for the quality and precision of the final pipe during the process of stretch-reducing of the seamless pipe. The inhomogeneous deformation of the pipe may occur if the reducing rate distribution is improper. This paper analyzed the trend of the reducing rate distribution in terms of metal flow and put forward a “three-point and two-section converged” correction theory based on relevant research. In order to verify the theory, the finite element model is established according to the results obtained from the modified model. The simulation is accomplished successfully, and the cross-section of the pipe is evenly reduced with the longitudinal metal flowing uniformly. The result from the experiment is consistent with that from the simulation, which shows the rationality of this theory, providing a new method for the reduction rate allocation.
Sr Doping and Oxygen Vacancy Formation in La1−xSrxScO3−δ Solid Solutions: Computational Modelling
Authors: Mastrikov Yuri , Gryaznov Denis , Zvejnieks Guntars , Sokolov Maksim , Putniņa Māra , Kotomin Eugene
Published: September 2022

Sr-doped lanthanum scandate La1−xSrxScO3−δ (LSS) is a promising perovskite-type material for electrochemical applications such as proton conductors. Oxygen vacancy is a common defect in ABO3-type perovskites. It controls ion transport as well as proton uptake. The energetic, structural, and electronic properties of oxygen vacancy in LSS are studied deploying the DFT method with meta-GGA functional. The vacancy formation energies in LSS were calculated for various Sr concentrations. Unlike other perovskites, in this material, the electrons are trapped at the oxygen vacancy site (the F-type centres, common in ionic oxides like MgO and Al2O3) rather than localised on the nearest to the vacancy B-cations. The process of oxygen vacancy formation is considered relative to Sr concentration x and oxygen nonstoichiometry factor δ. Three primary regimes are discussed: (I) localized at the vacancy electrons, x/δ < 2, (II) electron charge balanced system, x/δ = 2, and (III) delocalized electron holes, x/δ > 2. For x/δ ≥ 2 oxygen vacancy formation energy reaches the saturation level of ~3.5 eV, which is potentially beneficial for the proton uptake.
Effect of Gate Dielectric Material on the Electrical Properties of MoSe2-Based Metal–Insulator–Semiconductor Field-Effect Transistor
Authors: Abderrahmane Abdelkader , Jung Pan-Gum , Woo Changlim , Ko Pil Ju
Published: September 2022

In this study, we fabricated metal–insulator–semiconductor field-effect transistors (MISFETs) based on nanolayered molybdenum diselenide (MoSe2) using two insulator materials, silicon dioxide (SiO2) and silicon nitride (SiN). We performed morphological and electrical characterizations in which the devices showed good electronic performance, such as high mobility and high Ion/Ioff ratios exceeding 104. The subthreshold swing (ss) was somewhat high in all devices owing to the dimensions of our devices. In addition, the transfer curves showed good controllability as a function of gate voltage. The photogating effect was weakened in MoSe2/SiN/Si, indicating that SiN is a good alternative to silicon oxide as a gate dielectric material.
The COLIBAS Study—COVID-19 Lockdown Effects on Mood, Academic Functioning, Alcohol Consumption, and Perceived Immune Fitness: Data from Buenos Aires University Students
Authors: Hendriksen Pauline A. , Kiani Pantea , Merlo Agnese , Karadayian Analia , Czerniczyniec Analia , Lores-Arnaiz Silvia , Bruce Gillian , Verster Joris C.
Published: September 2022

A recent study was conducted in the Netherlands to evaluate the impact of the 2019 coronavirus (COVID-19) pandemic and its associated lockdown periods on academic functioning, mood, and health correlates such as alcohol consumption. The study revealed that lockdowns were associated with a significantly poorer mood and a reduced perceived immune fitness. Overall, a reduction was seen in alcohol consumption during the lockdown periods. Academic functioning in terms of performance was unaffected; however, a significant reduction in interactions with other students and teachers was reported. There was, however, great variability between students as follows: both an increase and a reduction in alcohol consumption were reported, as well as improvements and poorer academic functioning. The aim of the current online study was to replicate these findings in Argentina. To this extent, a modified version of the survey was conducted among students at the University of Buenos Aires, which was adapted to the local lockdown measures. The survey assessed possible changes in self-reported academic functioning, mood, and health correlates, such as alcohol consumption, perceived immune functioning, and sleep quality compared to before the COVID-19 pandemic. Retrospective assessments were made for four periods, including (1) the period before COVID-19, (2) the first lockdown period (March–December 2020), (3) summer 2021 (January-March 2021, no lockdown), and (4) the second lockdown (from April 2021 to July 2021). This article describes the content of the survey and the corresponding dataset. The survey was completed by 508 participants.
Cotton Yield Estimation Using the Remotely Sensed Cotton Boll Index from UAV Images
Authors: Shi Guanwei , Du Xin , Du Mingwei , Li Qiangzi , Tian Xiaoli , Ren Yiting , Zhang Yuan , Wang Hongyan
Published: September 2022

Cotton constitutes 81% of the world’s natural fibers. Accurate and rapid cotton yield estimation is important for cotton trade and agricultural policy development. Therefore, we developed a remote sensing index that can intuitively represent cotton boll characteristics and support cotton yield estimation by extracting cotton boll pixels. In our study, the Density of open Cotton boll Pixels (DCPs) was extracted by designing different cotton boll indices combined with the threshold segmentation method. The relationship between DCP and field survey datasets, the Density of Total Cotton bolls (DTC), and yield were compared and analyzed. Five common yield estimation models, Linear Regression (LR), Support Vector Regression (SVR), Classification and Regression Trees (CART), Random Forest (RF), and K-Nearest Neighbors (KNN), were implemented and evaluated. The results showed that DCP had a strong correlation with yield, with a Pearson correlation coefficient of 0.84. The RF method exhibited the best yield estimation performance, with average R2 and rRMSE values of 0.77 and 7.5%, respectively (five-fold cross-validation). This study showed that RedGreenBlue (RGB) and Near Infrared Red (NIR) normalized, a normalized form index consisting of the RGB and NIR bands, performed best.
Smart Photovoltaic Energy Systems for a Sustainable Future
Authors: Efthymiou Venizelos , Papadimitriou Christina N.
Published: September 2022

This book is the result of a concerted effort to shed scientific light on the timely theme of “Smart Photovoltaic Energy Systems for a Sustainable Future” [...]
A Conspiracy with Twelve-Year-Old Jane Austen: Juliet McMaster’s Illustrations for ‘The Beautifull Cassandra’
Authors: Hisamori Kazuko
Published: September 2022

This article discusses a picture book, The Beautifull [sic] Cassandra, that was published by Juvenilia Press in 2021. The text was written by Jane Austen, most probably in 1788, and was edited and illustrated by Juliet McMaster some 200 years later. My key questions are: What are the characteristics of Austen’s text? What are the strategies that McMaster uses to illustrate the text? How do we evaluate the picture book as a whole?
Comparison of Digital Interactive Case-Based Educational Resource with Virtual Role Play in Dental Undergraduates in Clinical Oral Medicine/Oral Pathology Education
Authors: Tee Wen Xi , Tan Siew Huey , Marican Fareeza , Sidhu Preena , Yerebairapura Math Swarna , Gopinath Divya
Published: September 2022

Case-based learning has always been a key element of dental education and the incorporation of technology into the concept became increasingly important during the COVID-19 pandemic. This study aimed to compare the effectiveness of a virtual interactive case resource in oral medicine/oral pathology, Virtual Oral Medicine Clinic (VOMC), with the virtual role play among third-year dental undergraduates. Fifty-one students were randomly assigned into two groups and the control group was subjected to a role play activity, whereas the experimental group was provided with VOMC. Both groups were assessed with an objective structured clinical examination (OSCE) before and after the intervention. Students’ self-perceived usefulness of the interventions was evaluated by a questionnaire and randomly selected students were invited for focus group discussions. Data were analysed using the Wilcoxon signed-rank test and the Mann–Whitney U test. Descriptive statistics were used to analyse student responses. Students in both groups demonstrated significant improvement (p < 0.001) in the post-test compared to the pre-test. Students in the experimental group demonstrated higher overall scores (p < 0.001) when compared to the control group. Though both methods were received favourably by the students, role play was more positively perceived when compared to digital resource. Though VOMC was shown to improve student scores, the perception of VOMC was not quantitatively superior to the role play activity. Hence VOMC can be recommended as an adjunct tool to enhance learning in oral medicine in undergraduate dental students.
Comparison of INTEGRA and the Manual Method to Determine the Axis for Intraocular Lens Implantation—A Case Series of 60 Eyes
Authors: Jaworski Marcin , Wyględowska-Promieńska Dorota , Jaworski Piotr , Kowalski Michał , Jaskot Krzysztof , Bieda Robert
Published: September 2022

(1) Background: To compare the results of a new intraoperative contactless device (INTEGRA Optomed, Poland) with the result of a manual method for determining the axis for toric intraocular lens implantation. (2) Material and Methods: This retrospective observational study included 60 eyes of 40 patients (17 men, 23 women) who had toric intraocular lenses implanted. A video recording of each surgery that used the INTEGRA system was made for the analysis. Two researchers then independently assessed the location of the implant axes determined with both digital and manual slit-lamp methods, and compared the results between methods. (3) Results: The implantation axes suggested through the manual and INTEGRA methods were similar. The median axis disparities were 0.0 degrees for both groups. The standard deviation was 0.63 and 0.75 for researcher 1 and 2, respectively. The dominant value was 0.0 in both groups. The INTEGRA axis designation was statistically significantly different from the manual method for researcher 1 (p < 0.05), but it was statistically insignificant for researcher 2 (p = 0.79). (4) Conclusions: The INTEGRA system is a digital ink-free device for image tracking scleral vessels. It was helpful for determining the implantation axis in a precise manner, and the measurements were comparable with those obtained through a manual technique.
Comparative Study of Different Crassulaceae Species for Their Potential Use as Plant Covers to Improve Thermal Performance of Green Roofs
Authors: Gurrea-Ysasi Gonzalo , Blanca-Giménez Vicente , Fernández de Córdova Pascual , Cortés-Olmos Carles , Rodríguez-Burruezo Adrián , Fita Inmaculada C.
Published: September 2022

The presence of green roofs in urban areas improves the energy efficiency of buildings; contributes to the capture of CO2, decreasing pollution; and improves the appearance of cities, increasing their sustainability. Additionally, green roofs must include plant species with low requirements and maintenance, and thus, succulent species could be useful in Mediterranean semi-arid regions. In this work, the thermal inertia and the effect of different succulent species as thermal barriers on mitigating the increase in temperature inside experimental compartments were studied in comparison to conventional covers used in the Spanish Mediterranean for a whole year. In general, green covers were more efficient than conventional ones for controlling temperature. Thus, temperatures under green covers were up to 8 °C lower than conventional covers and 3–5 °C lower than the ambient temperature at noon on summer days. Furthermore, significant differences were found between green covers. Thus, despite having high thermal inertia, Aptenia cordifolia showed the worst temperature records, while Aeonium arboreum was the most efficient at mitigating temperature changes both on cold winter nights and hot summer days—even better than Sedum spp., a usual succulent used commercially. Our results demonstrate that succulent species are efficient materials to use as green covers to improve thermal conditions in buildings in Mediterranean cities. This also suggests that the mixture of succulent species (i.e., not only made of Sedum spp.) with different colors and textures could beautify green roofs without compromising their energy efficiency.
Disease Recurrence during Adjuvant Immune Checkpoint Inhibitor Treatment in Metastatic Melanoma: Clinical, Laboratory, and Radiological Characteristics in Patients from a Single Tertiary Referral Center
Authors: Kurzhals Jonas K. , Klee Gina , Hagelstein Victoria , Zillikens Detlef , Terheyden Patrick , Langan Ewan A.
Published: September 2022

Despite the dramatic improvements in recurrence-free survival in patients with metastatic melanoma treated with immune checkpoint inhibitors (ICI), a number of patients develop metastases during adjuvant therapy. It is not currently possible to predict which patients are most likely to develop disease recurrence due to a lack of reliable biomarkers. Thus, we retrospectively analyzed the case records of all patients who commenced adjuvant ICI therapy between January 2018 and December 2021 in a single university skin cancer center (n = 46) (i) to determine the rates of disease recurrence, (ii) to examine the utility of established markers, and (iii) to examine whether re-challenge with immunotherapy resulted in clinical response. Twelve out of forty-six (26%) patients developed a relapse on adjuvant immunotherapy in our cohort, and the median time to relapse was 139 days. Adjuvant immunotherapy was continued in three patients. Of the twelve patients who developed recurrence during adjuvant immunotherapy, seven had further disease recurrence within the observation period, with a median time of 112 days after the first progress. There was no significant difference comparing early recurrence (<180 days after initiation) on adjuvant immunotherapy to late recurrence (>180 days after initiation) on adjuvant immunotherapy. Classical tumor markers, including serum lactate dehydrogenase (LDH) and S-100, were unreliable for the detection of disease recurrence. Baseline lymphocyte and eosinophil counts and those during immunotherapy were not associated with disease recurrence. Interestingly, patients with NRAS mutations were disproportionately represented (60%) in the patients who developed disease recurrence, suggesting that these patients should be closely monitored during adjuvant therapy.
Experimental Phaeohyphomycosis of Curvularia lunata
Authors: Al-Odaini Najwa , Pan Kai-su , Liao Liu-wei , Mo Nan-fang , Jiang Zhi-wen , Li Tian-tian , Li Xiu-ying , He Xiao-juan , Zheng Dong-yan , Cao Cun-wei
Published: September 2022

Originally considered to be a plant pathogen, reports of phaeohyphomycosis due to Curvularia lunata (C. lunata) in animals and humans are increasing. However, studies on the pathogenesis, virulence, and epidemiology of C. lunata have rarely been discussed. In the present study, BALB/c mice were experimentally inoculated with C. lunata suspension by different routes and the course of infection was evaluated. In addition, the in vitro antifungal susceptibility of C. lunata against six commonly used antifungals was evaluated using the microdilution method. Inoculation resulted in skin lesions in animals inoculated intraperitonially and subcutaneously. Infection was confirmed by both mycological and histopathologic examination. C. lunata spores and hyphae were detected in the histopathologic sections stained with hexamine silver staining. In addition, voriconazole (VRC) demonstrated greater activity against C. lunata when compared to the other antifungals, whereas fluconazole (FLC) was the least active antifungal with a minimum inhibitory concentration (MIC) range of 8–16 μg/mL. Further studies are necessary to understand the pathogenicity of C. lunata and uncover the mystery of this fungus.
High-Frequency Dependence of Acoustic Properties of Three Typical Sediments in the South China Sea
Authors: Wang Jingqiang , Hou Zhengyu , Li Guanbao , Kan Guangming , Liu Baohua , Meng Xiangmei , Hua Qingfeng , Sun Lei
Published: September 2022

The acoustic characteristics of three fine-grained sediments (silty sand, silt, silty clay) in the South China Sea (SCS) were measured and analyzed at high frequency range of 27–247 kHz. The measurement results show that the sound speed dispersion is a positive linear relation at the measured frequency range, and the attenuation follows nonlinear frequency dependence, α = kfn, where n ranges from 0.59 to 0.85 for the three different sediments in the SCS. The frequency dependence of sound speed and attenuation were compared with the published literature. It was found that for silty clay, clayey silt, silt, and silty sand, the dispersion characteristics of these four sediments are basically consistent; in general, the dispersion of coarse particles is significant, and that of fine particles is weak, and permeability is the key parameter that determines the inflection point of high frequency to low frequency. By modeling these sediments with the Biot–Stoll model, it was found that the Biot–Stoll model can better predict the frequency-dependent characteristics of sound attenuation in a high-frequency band under the matching constraints of sound speed dispersion characteristics, indicating that the Biot–Stoll model has good applicability to different types of sediments in a high-frequency band.
The Spatial Pedigree in Traditional Villages under the Perspective of Urban Regeneration—Taking 728 Villages in Jiangnan Region, China as Cases
Authors: Liu Xinqu , Li Yaowu , Wu Yongfa , Li Chaoran
Published: September 2022

In current urban regeneration, the conservation and reuse of traditional village space are significant measures to activate urban-rural development. Traditional villages in the Jiangnan region of eastern China represent the typical vernacular culture of urban-rural settlements, which affects the dynamic development of urban regeneration. Aiming at the disadvantages of the decentralization of research objects and the simplification of spatial characteristics in the research of traditional villages in the Jiangnan region, this paper will construct the spatial pedigrees of villages. This study takes 728 traditional villages in the Jiangnan region as cases. First, through on-site research, the spatial pattern of villages in isolated areas was mapped and drawn. Then, on the basis of on-site review, this study labeled the village space, summarized village space information, and used ArcGIS and BIM to create a 3D model of the village. In ArcGIS platform through SOA to establish criterion framework for recognizing the types of village pedigree. Finally, the classification of villages was spatially visualized, and a pedigree was constructed according to the type context. The research result indicates: (1) The aggregation mode of traditional villages in the south of the Jiangnan region presents the characteristics of local aggregation and partial dispersion, which are directly affected by factors such as elevation, water system, and road system. (2) Analysis of the spatial pedigrees of traditional villages through spatial types and spatial growth patterns revealed four pedigree types, including spatial environment pedigree, the spatial organization pedigree, spatial morphological pedigree, and architectural form pedigree. (3) The pedigree shows and distinguishes independent developmental context and evolved form, presenting an extended pattern of prototypes and sub-types.
Numerical Simulation of Local Buckling of Submarine Pipelines under Combined Loading Conditions
Authors: Su Wenxian , Ren Jie
Published: September 2022

Submarine pipelines are prone to developing flaws, such as ellipticity and depression during the manufacture, burying, and use processes. The local buckling characteristics of submarine pipelines with initial imperfection must be studied since the initial imperfection have an impact on local pipeline buckling. In this study, the local buckling of submarine pipelines with varying depression depths and ellipticity is simulated using the finite element program ABAQUS, and defect sensitivity of submarine pipelines with varying shape ellipticity, varying depression depths, and varying pipe radius-thickness ratios is examined. Meanwhile, research is being conducted on the combined load buckling of a submarine pipeline with initial imperfection caused by bending, axial force, and external hydrostatic pressure. The results indicated that the critical external pressure of the pipeline is sensitive to the imperfection, although the buckling propagation pressure is not. The buckling morphology is influenced by the shape and size of the imperfection. Additionally, the ability to withstand external hydrostatic pressure of the pipeline reduces after it has been bent.
Stabilization for Stochastic Coupled Kuramoto Oscillators via Nonlinear Distributed Feedback Control
Authors: Kang Rui , Gao Shang
Published: September 2022

This paper investigates the stabilization for stochastic coupled Kuramoto oscillators (SCKOs) via nonlinear distributed feedback control. An original nonlinear distributed feedback control with the advantages of fast response, no steady-state deviation, and easy implementation is designed to stabilize SCKOs. With the help of the Lyapunov method and stochastic analysis skills, some novel sufficient conditions guaranteeing the stochastic stability for SCKOs are provided by constructing a new and suitable Lyapunov function for SCKOs. Finally, a numerical example is given to illustrate the effectiveness and applicability of the theoretical result.
Dietary Efficacy Evaluation by Applying a Prediction Model Using Clinical Fecal Microbiome Data of Colorectal Disease to a Controlled Animal Model from an Obesity Perspective
Authors: Seo Hochan , Kwon Cheol-O , Park Joo-Hyun , Kang Chil-Sung , Shin Tae-Seop , Yang Eun-Young , Jung Jin Woo , Moon Byoung-Seok , Kim Yoon-Keun
Published: September 2022

Obesity associated with a Western diet such as a high-fat diet (HFD) is a known risk factor for inflammatory bowel disease (IBD) and colorectal cancer (CRC). In this study, we aimed to develop fecal microbiome data-based deep learning algorithms for the risk assessment of colorectal diseases. The effects of a HFD and a candidate food (Nypa fruticans, NF) on IBD and CRC risk reduction were also evaluated. Fecal microbiome data were obtained from 109 IBD patients, 111 CRC patients, and 395 healthy control (HC) subjects by 16S rDNA amplicon sequencing. IBD and CRC risk assessment prediction models were then constructed by deep learning algorithms. Dietary effects were evaluated based on fecal microbiome data from rats fed on a regular chow diet (RCD), HFD, and HFD plus ethanol extracts or water extracts of NF. There were significant differences in taxa when IBD and CRC were compared with HC. The diagnostic performance (area under curve, AUC) of the deep learning algorithm was 0.84 for IBD and 0.80 for CRC prediction. Based on the rat fecal microbiome data, IBD and CRC risks were increased in HFD-fed rats versus RCD-fed rats. Interestingly, in the HFD-induced obesity model, the IBD and CRC risk scores were significantly lowered by the administration of ethanol extracts of NF, but not by the administration of water extracts of NF. In conclusion, changes in the fecal microbiome of obesity by Western diet could be important risk factors for the development of IBD and CRC. The risk prediction model developed in this study could be used to evaluate dietary efficacy.
Genetic Diversity of Pectobacterium spp. on Potato in Serbia
Authors: Loc Marta , Milošević Dragana , Ivanović Žarko , Ignjatov Maja , Budakov Dragana , Grahovac Jovana , Grahovac Mila
Published: September 2022

Pectobacterium is a diverse genus which comprises of multiple destructive bacterial species which cause soft rot/blackleg/wilt disease complex in a wide variety of crops by employing high levels of virulence factors. During the 2018, 2019 and 2020 potato growing seasons, numerous outbreaks of bacterial wilt, stem blackleg and tuber soft rot were recorded, and symptomatic plant samples from ten localities in the Province of Vojvodina (Serbia) were collected and analysed. Bacterial soft-rot pathogens were detected in 63 samples using genus and species-specific primers. Through 16S rRNA Sanger sequencing of 19 representative isolates, the identity of P. brasiliense (73.7%), P. punjabense (15.8%), and P. carotovorum (10.5%) species were revealed. To further validate the identification, genotypic profiling of Pectobacterium strains using rep-PCR (ERIC, BOX, REP) was conducted for 25 selected isolates and the phylogenetic assessment based on four selected housekeeping genes (gyrA, recA, rpoA, and rpoS). Physiological and biochemical properties were analysed using basic microbiological tests and VITEK® 2 GN card, and pathogenicity was confirmed on cv. VR808 and cv. Desiree potato tubers and plants. This study confirmed the distinctiveness of the newly described P. punjabense in Serbia as well as the high diversity of Pectobacterium brasiliense and Pectobacterium carotovorum species in Serbia.
A Review of the Dawn of Benchtop EPR Spectrometers—Innovation That Shaped the Future of This Technology
Authors: Ptushenko Vasily V. , Linev Vladimir N.
Published: September 2022

By the early 1980s, unique devices appeared in the USSR: a series of benchtop specialized EPR spectrometers. This equipment was quickly accepted not only in science but also in medicine and in many technical and economic areas including chemical industries and geologic exploration. The appearance of these devices was perceived as a salvation for the Soviet magnetic resonance (MR) scientific instrumentation by those who worked in the field of EPR spectroscopy in the USSR. (However, the program of MR scientific instrumentation ceased to exist along with the USSR a few years later). The Belarusian State University in Minsk was the center of these developments. At that moment and for many years afterwards, these devices were unique with no analogues in the worldwide EPR industry. They remained the only mass-produced MR spectrometers on the territory of the former USSR after its collapse. For the first time, based on archival materials, patents, and our personal memoirs, we describe the development of these EPR spectrometers and discuss the most original technical solutions and the scientific tasks solved with this equipment We also remember the participants of the work, showing the historical context of these events.
Relation between Experience Categories and Psychological Needs
Authors: Haspel Christina , Laib Magdalena , Early Leslie-Ann , Burmester Michael
Published: September 2022

Knowledge about human behaviour and motivation is essential for designing a positive user experience (UX). Theories of psychological needs have been profoundly researched and well-established in UX research. Experience categories are a rather new practical human-centred design method; they are not based on a psychological model, but instead on an empirical approach. Experience categories describe common positive experiences in a particular context. According to Hassenzahl, positive experiences result from the fulfilment of psychological needs. However, there has been no research on how experience categories and needs are associated. To fill this gap and enrich the knowledge about experience categories, we investigated which needs co-occur with them. In Study 1, we used a more general approach: experience categories of work context were operationalised with scenarios that were rated with a needs questionnaire. In Study 2, we aimed to replicate the findings of Study 1 in a more specific work context by investigating the relationship between experience categories and needs for an existing sample of experiences. Results show a consistent relationship between some experience categories and needs in both studies. Moreover, the need for competence was particularly relevant in the work context. Future studies should expand on this research to further work contexts.
CGA-VLP: High Accuracy Visible Light Positioning Algorithm Using Single Square LED with Geomagnetic Angle Correction
Authors: Yang Chen , Wen Shangsheng , Yuan Danlan , Chen Junye , Huang Junlin , Guan Weipeng
Published: September 2022

Visible light positioning (VLP), benefiting from its high accuracy and low cost, is a promising technology for indoor location-based services. In this article, the theoretical limits and error sources of traditional camera-based VLP systems are analyzed. To solve the problem that multiple LEDs are required and auxiliary sensors are imperfect, a VLP system with a single square LED which can correct the geomagnetic angle obtained from a geomagnetic sensor is proposed. In addition, we conducted a static positioning experiment and a dynamic positioning experiment integrated with pedestrian dead reckoning on an Android platform to evaluate the effectiveness of the proposed method. According to the experimental results, when the horizontal distance between the camera and the center of the LED is less than 120 cm, the average positioning error can be retained within 10 cm and the average positioning time on the mobile phone is 39.64 ms.
Experimental Investigation on Flow Characteristics and Ignition Performance of Plasma-Actuated Flame Holder
Authors: Jia Min , Zang Yinxiang , Cui Wei , Lin Dong , Zhang Zhibo , Song Huimin
Published: September 2022

Improving the performance of flame holders has been a key focus of research on ramjet combustors. The plasma actuator has the potential to improve the ignition performance by manipulating the flow field of the flame holder. In this study, a plasma-actuated flame holder was designed. The aim of this study is to improve the performance of ramjet combustor by applying plasma discharge to the flame holder. The aerodynamic effects and ignition performance of the flame holder were investigated. The results demonstrated that the induced jet direction of the surface arc discharge was perpendicular to the actuator. The induced jet dissipated faster at lower pressures. The aerodynamic actuation intensity and jet area increased with the number of channels of surface arc discharges. Increasing discharge frequencies can increase the discharge times and jet height. The aerodynamic effects under a microsecond pulse duration were better than those under a nanosecond pulse duration. Actuators installed on the inside surface showed better performance than those installed outside. Under different total flow temperature conditions, the plasma-actuated flame holder significantly extended the ignition pressure limit and increased the combustion efficiency by 9.12% and 4.3% on average, respectively.
Mass or Count Noun: Latin Considerations of the Use of sanguis in the Plural
Authors: Grondeux Anne
Published: September 2022

Educated by generations of grammarians who state that the term sanguis (blood) is used only in the singular, Fathers of the Church, exegetes, and commentators were confronted with about twenty scriptural, essentially veterotestimentary tokens where sanguis is used in the plural. Justifications for this particular use appear throughout the commentaries. My study will attempt to answer a series of questions. Which passages interested the commentators the most and why? Which grammarians were involved and in what respect? What kind of justifications were provided? Was their interest purely hermeneutic or did the exegetes aim to preserve a state inherited from scrupulous translations? Were the passages treated in isolation or set in resonance? Does this assessment of the commentaries allow us to identity filiations? It will also be seen that this matter is another piece of the puzzle in the relationship between grammar and faith.
Short-Term HRV Detection and Human Fatigue State Analysis Based on Optical Fiber Sensing Technology
Authors: Hu Siqi , Lin Huaguan , Zhang Quanqing , Wang Sheng , Zeng Qingbing , He Sailing
Published: September 2022

Mental fatigue is a key cause of chronic diseases and traffic accidents, which is difficult to be quantitatively evaluated. In order to non-intrusively detect fatigue state, an optical fiber sensing system is proposed, which is non-invasive and does not require direct contact with skin. The fiber sensor was fabricated through phase mask exposure method and packaged by sensitivity-enhanced structure, which can suppress transverse force and increase signal amplitude by 5%. A fatigue-inducing experiment was carried out, and the heartbeat signals of 20 subjects under different fatigue states were collected by the proposed sensing system. A series of heart rate variability indicators were calculated from the sensing signals, and their statistical significance for fatigue was analyzed. The experiment results showed that the values of SDNN and LF/HF increased significantly with subjects’ fatigue level. This study shows that the proposed fiber optic sensing system has practical value in fatigue state monitoring.
Spatial Pattern Simulation of Antenna Base Station Positions Using Point Process Techniques
Authors: Zimeras Stelios
Published: September 2022

Spatial statistics is a powerful tool for analyzing data that are illustrated as points or positions in a regular or non-regular state space. Techniques that are proposed to investigate the spatial association between neighboring positions are based on the point process analysis. One of the main goals is to simulate real data positions (such as antenna base stations) using the type of point process that most closely matches the data. Spatial patterns could be detailed describing the observed positions and appropriate models were proposed to simulate these patterns. A common model to simulate spatial patterns is the Poisson point process. In this work analyses of the Poisson point process—as well as modified types such as inhibition point process and determinantal Poisson point process—are presented with simulated data close to the true data (i.e., antenna base station positions). Investigation of the spatial variation of the data led us to the spatial association between positions by applying Ripley’s K-functions and L-Function.
Dimensiones del valor en el recurso hídrico
Authors: Silva-Hernández Francisca
Published: September 2022

El agua u “oro azul” constituye para la humanidad su supervivencia y posteridad como especie, la importancia o valor agregado que tiene este recurso es vital a nivel global. Debido a su importancia este documento versa sobre la descripción y análisis del Informe Mundial de las Naciones Unidas sobre el Desarrollo de los Recursos Hídricos, respecto a la clasificación del recurso hídrico por dimensiones, en el que permite identificar la postura de Naciones Unidas basada en la construcción de documentos institucionales u oficiales los cuales integran elementos descriptivos para comprender dichas dimensiones de forma sostenible, transversal y multidisciplinaria, con el afán de abonar a la construcción, gestión y desarrollo de una cultura del agua para su conservación, buen manejo y consumo, como un bien común en que la relación de Estado-Sociedad debe conjugar y actuar de manera precautoria y preventiva para la generación del presente y futuro.
Technologies and methods of business processes analysis and optimization
Authors: Aleksandrovich-Adamenko Aleksandr , Evgenievna-Khorolskaya Tatiana , Viktorovna-Koneva Marina
Published: September 2022

The process approach to management is based on the automation of various aspects of the company's activities. The formation, optimization, restructuring and improvement of business processes are taking place along with the introduction of applied systems (most often, on 1C: Enterprise platform). Nevertheless, business analysts play a key role in optimizing a company's business processes. The study intends to scrutinize the technologies and methods of business processes analysis and optimization.  To that end, monographic, economic-statistical, and abstract-logical methods are employed. Based on the results, in the context of the optimization methodology, optimization can be considered in the framework of progressive improvement or reengineering of business processes (global, large-scale revision of the system). The study of the optimization methodology for business processes revealed several elements of this process, including the choice of methods of analysis and optimization of business processes, ranking of business processes by their importance to show priority processes to start optimization with, and finally, development of a system of key performance indicators to link the personnel motivation system with the achievement of tactical and strategic goals of the company.
Formation and development of the innovation potential of the company’s employees
Authors: Fedoseevich-Borisov Alexander , Vasilyevich-Vorontsov Alekcey , Vladimirovich-Kurtyak Ivan , Leonidovna-Rasina Maria , Alexandrovna-Trofimova Tatiana
Published: September 2022

This article explores the innovation potential of the staff at industrial enterprises. One of the main goals of the research was determining the factors influencing the development of the innovative potential of the company's employees. The authors analyzed the company's internal regulatory documents that regulate the enterprise's innovation policy. The relevance of the research is confirmed by the increasing interest of companies in innovation. This manifests itself both in the changing organizational structure of enterprises and a new approach to human resource management, for instance, the revision of the key performance indicators of employees. Some authors mention that the changes and social transformations determine the need for organizations to search for alternatives that can improve performance, facilitate the achievement of goals and improve the provision of services. This confirms the relevance of the research topic and the need to study the factors influencing the development of the innovative potential of the employees. Having analyzed the internal documents regulating the innovation policy of the enterprise, we determined the organizational structure of the innovation management and the stakeholders. Thus, we could propose targeted recommendations and determine how to improve the system to develop the innovation potential of the staff.
Using the quadruple aim to understand the impact of virtual delivery of care within Ontario community health centres: a qualitative study
Authors: Bhatti Sara , Dahrouge Simone , Muldoon Laura , Rayner Jennifer
Published: September 2022

Background

The onset of the COVID-19 pandemic and introduction of various restrictions resulted in drastic changes to 'traditional' primary healthcare service delivery modalities.

Aim

To understand the impact of virtual care on healthcare system performance within the context of Ontario community health centres (CHCs).

Design & setting

Thematic analysis of qualitative interviews with 36 providers and 31 patients.

Method

Semi-structured phone interviews were conducted in the autumn of 2020. Interviews were recorded, transcribed verbatim, and analysed thematically using the quadruple aim framework.

Results

The transition to virtual delivery of services has had both positive and negative impacts on care. Virtual care removed certain barriers to care such as access. However, patients and providers found that phone visits impacted quality of care owing to the inability to read body language and having to rely solely on patient descriptions. Video visits allowed for a similar experience to in-person visits but technical issues constrained this interaction. Depending on the service provided, some providers felt they were not providing the same quality of care. However, providers reported reductions in no-show rates and highlighted the efficiency of virtual appointments. Providers also found they were able to collaborate at a similar level before the pandemic and saw improvements in work–life balance. Overall, patients and providers alike preferred virtual visits with those known to them, and for less complex or transactional aspects of care.

Conclusion

The study described positive and negative impacts on patient care, population health, health system costs, and provider experience. These results will be useful for primary care organisations in post-pandemic planning; however, future research is needed for a deeper exploration of the impact on quality of care specifically for more complex health concerns.
The mental health detention process: a scoping review to inform GP training
Authors: Houton Paula , Reid Helen , Davidson Gavin , Gormley Gerard
Published: September 2022

Background

GPs are often faced with deciding whether or not a patient may require detention for assessment in hospital under mental health legislation. This can be a complex and daunting process. Despite this, GPs and most other professionals receive limited formal training.

Aim

To map and review the current literature on training in mental health detention processes. These insights are vital to inform the further development of meaningful educational approaches.

Design & setting

A systematic scoping literature review was conducted to identify what is known about how best to develop training in this area.

Method

Arksey and O’Malley’s framework was used to select, chart, and analyse articles from across six electronic databases. A total of 1136 articles were included in the initial screening phase and 183 articles were included in the full-text screening phase. Key themes were derived using an iterative and thematic approach. A personal and public involvement (PPI) group was set up for this project and other stakeholders in the mental health detention process were consulted about the findings.

Results

Fifty-two articles were included in the final review. Professionals consistently highlighted unmet training needs and difficulties with the process. There were identified needs for practical, interdisciplinary training, including discussion of complex cases, and opportunities to learn from those with direct experience.

Conclusion

This work is foundational for the development of meaningful educational approaches around mental health detention processes. A strong research base will inform and strengthen training with the ultimate aim of improving patient care.
Hubungan Pengetahuan dan Sikap Pasangan Usia Subur dalam Alat Kontrasepsi Dalam Rahim
Authors: Fathiyatu Diyanah Syifa , Susiloningtyas Is , Sutrisminah Emi
Published: September 2022

Long-term highly effective reversible contraceptive methods have historically increased in popularity and declined in different regions of the world. The decrease in the number of AKDR participants every year is due to several factors, one of which is ignorance about the advantages of contraceptives in the womb where knowledge and attitudes in choosing contraception become influential considerations in determining the method of contraception to be used. This review literature aims to conduct a review of the articles of research results over the past 10 years to find out the relationship of knowledge and attitudes of Couples of Childbearing Age in the use of Intraute Contraceptives especially IUDs. Methods used with foreign and local review literature are searched through electronic media online and use Google scholar, Sinta, and Pubmed data base using keywords. The results showed that there is a relationship between knowledge and attitudes of Couples of Childbearing Age in using Intrauteute Contraceptives. The conclusion of this study is that there is a relationship between knowledge and attitudes of Couples of Childbearing Age in the use of Contraceptives in the Womb