bluuebunny/crossref_metadata_2025 huggingface dataset:
ARŞİV BELGELERİ IŞIĞINDA GİRESUN-TİREBOLU REDİF DEPOSU VE REDİF DAİRESİ
Authors: BAYHAN Ahmet Ali , YILDIRIM GÜNEŞ Özgül
Published: November 2021

Osmanlı Devleti’nin Batılılaşma sürecinde başta askeri alanda olmak üzere birçok noktada yenilik ve düzenlemelere gidilmiştir. 1834’te yapılan askeri düzenlemelerde ise II. Mahmud’un Yeniçeri Ocağını kaldırdıktan sonra kurduğu Asâkir-i Mansûre-i Muhammediyye ordusuna taşrada yardım etmek için redif teşkilatı oluşturulmuştur. Taşradaki bu askeri teşkilata bağlı birliğin ihtiyaçlarını karşılayabilecek ve askeri düzeninin de sistematik biçimde ilerlemesine fayda edecek redif binaları, Anadolu’nun birçok yerinde inşa edilmiştir. Giresun Tirebolu’da ise bir redif deposu ve günümüze ulaşamayan bir redif dairesi Cumhurbaşkanlığı Osmanlı Arşivlerindeki muhtelif belgelerle ilk kez tespit edilmiştir. Çalışmanın amacı tespit edilen bu iki yapının işlev ve mimari özelliklerini çizim-fotoğraf gibi materyallerle değerlendirmek ve tanıtmak ayrıca askeri yapılara yönelik çalışmalara katkı sunmaktır.
Factores que inciden en la innovación organizacional de las Mipymes en México
Authors: Esparza Rodríguez Saul Alfonso
Published: November 2021

El presente trabajo muestra una investigación que argumenta acerca de la relevancia de los grupos de interés como fuentes internas y externas relevantes en el proceso de innovación organizacional, para lo cual se presentan los hallazgos obtenidos de la revisión de la literatura relativa sobre el tema, en donde se incluyen una serie de conceptos relacionados con esta forma de innovación, así como trabajos que muestran la relación de la gestión de grupos de interés con la innovación organizacional como base literaria para explicar la forma en cómo interactúan directa e indirectamente con las Mipymes mexicanas en este tipo de innovación. Con ese objetivo, se identifica que los stakeholders tales como administradores, empleados, clientes, proveedores, competidores, instituciones de crédito y gobierno, son partes interesadas relevantes en el proceso de innovación organizacional de las pequeñas y medianas empresas. La conclusión del trabajo propone que las múltiples interacciones entre grupos de interés de las Mipymes mexicanas son factores fundamentales que permiten comprender en mejor medida el entorno organizacional, tanto a nivel interno como externo, que explican la introducción de cambios orientados a mejorar el funcionamiento de estas empresas, y con ello, exponer la fundamental participación del administrador en esta dinámica organizacional.
Un gobierno basado en la felicidad
Authors: Lazcano Gutiérrez Iván
Published: November 2021

La aparición del libro de Roberto Castellanos viene a ocupar un vacío en la literatura de las Ciencias Sociales en México acerca del bienestar subjetivo. El objetivo de este trabajo es analizar la pertinencia y viabilidad del uso del bienestar subjetivo como criterio de decisión y conducción de la política pública en México. Fuera de algunos trabajos colectivos, quizás este libro sea la primera apreciación completa en la materia. Sin duda, fue un acierto la publicación de esta obra por parte del INAP, pues su claridad argumental lo convierte en una fuente de consulta obligada para todos aquel que desee trabajar el tema, tanto desde una perspectiva académica como del diseño de políticas públicas.
Prevalance of vitamin A, zinc, iodine deficiency and anaemia among 2-10 year-old Ghanaian children
Authors:   University of Ghana, Egbi Godfred
Published: November 2021

Children are the most nutritionally vulnerable group of society as children are dependants and they are also at a critical stage of the growing process. They need adequate vitamin A, zinc, iron and iodine for their development and school performance. Most often iron deficiency causes anaemia with resultant fatigue and low work capacity. Studies comprehensively assessed dietary intakes of nutrients among Ghanaian children but there is not enough data available on the biochemical assessment of the micronutrient status of Ghanaian children. Therefore, the study provided the first primary data on the prevalence of vitamin A, zinc, iron, iodine deficiency and anaemia among underprivileged 2 – 10 years Ghanaian children in Okwenya village of the Manya-Krobo District. The study was a cross-sectional study carried out among 101 children. Fasting blood sample was collected from each child and used to determine vitamin A, serum zinc and hemoglobin concentration. Urine sample was collected from each of the participants early in the morning and that was used to determine the participant’s urinary iodine concentration. Dietary intake data were collected with the 24-hour recalls method on two non consecutive days. Anthropometric data (weight and height measurements) and demographic data were collected on the participants. The prevalence of urinary iodine deficiency and anaemia among the children of Okwenya village was of public health concern. There was high prevalence of low urinary iodine, 93.8% (<100 µg/dl) and anaemia, 72.5% (hemoglobin <11.5g/dl) among the participants. The prevalence of vitamin A deficiency (serum retinol<20µg/dl), low serum zinc concentration <70µg/dl and low hair zinc concentration <70µg/g among the children was 35.6%, 40.5% and 29.9% respectively. There was 22.8% of the participants stunted (short for their age) in the study. This study the first nutritional assessment study in the community showed a high prevalence of low urinary iodine concentration and anemia among the children that were of public health interest. The findings also showed the prevalence of vitamin A deficiency and stunting among the children. From the findings there is the need for a nutritional intervention programme to improve the iodine, anaemia, vitamin A and general nutritional status of the children of Okwenya village.
Nutritional and health status of primary school children in rural Uganda
Authors:   Makerere University, Acham H , Kikafunda JK , Tylleskar T ,   University of Bergen, Malde MK ,   National Institute of Nutrition and Seafood Research, Bergen
Published: November 2021

Poor nutrition and health can affect children’s education. The nutritional status of school children (9-15 years) was assessed in Kumi district, Eastern Uganda in 2006-2007. Selection of schools was done using modified cluster sampling involving 34 schools (n=645). Assessments for nutritional status were done anthropometrically (height and weight), biochemically (iron, n=145; iodine, n=87; and vitamin A, n=145) and assessment for health status was done following the formal ether concentration technique for examination for intestinal helminths (n=189) and a quick malaria (n=119) test for malaria parasites. Prevalence rates for stunting, underweight and thinness were 8.7% (95CI 6.7-11.1); 13.0% (95CI 10.6-15.8); and 10.1% (95CI 7.9-12.6), respectively of which males and the older age group of children were more affected. Prevalence rates for iodine deficiency, anaemia, iron deficiency and vitamin A deficiency (VAD) were 3.4% (95CI 0.9-9.1); 24.1% (95CI 17.7-31.6); 82.1% (95CI 75.2-87.7); and 30.3% (95CI 23.3- 38.2), respectively. Anaemia (measured as haemoglobin status), iron deficiency (measured as serum Ferritin) and VAD (measured as serum retinol) were higher among females (26.3%, 95CI 17.5-36.7; 83.8%, 95CI 74.4-90.7; 33.8%, 95CI 24.0-44.6) compared to males (21.5%, 95CI 12.8-32.8; 80%, 95CI 69.0-88.4; 26.2%, 95CI 16.6-37.8). Geohelminth (S.mansoni & N.americanus) and malaria parasitemia were 4.8% and 46.2%, respectively. Prevalence rates for stunting, iodine deficiency and geohelminth infections were low. The high prevalence rates of wasting/thinness, underweight, iron and vitamin A deficiencies show these as significant public health problems among school children in Kumi district. There is a need to focus attention on nutritional and health conditions of school children to improve their conditions. Much can be done to prevent malaria infection by promoting the use of Insecticide Treated Nets and chemoprophylaxis. The biennial dosage with albendazole for deworming, and universal use of iodized salt in Uganda are success stories that should continue; iron deficiency anaemia can be controlled through nutrition education, provision of nutritious school meals coupled with control of malaria and deworming. Since many children attend school, such services if delivered through school systems would assist those school children who most need them.
Preservation of penicillium species by lyophilization
Authors:   University of the Punjab, Ibatsam K , Rukhsana B , Nasim G
Published: November 2021

The maintenance and production of reliable pure cultures with desirable quality is a key operation and the first significant stage in the success of fungal identification. This study assessed spawn preservation and lyophilization (freeze drying) of cultures, for a long time. The sampling was done during the years 2008-2010. Samples were processed in fungal research laboratory of First Fungal Culture Bank of Pakistan (FCBP), Institute of Agricultural Sciences, University of the Punjab, Lahore, Pakistan. Lyophilization has been used to stabilize living cells and fungal isolates, to dehydrate vast range of materials, including foodstuffs, pharmaceuticals, biotechnology products, vaccines, and diagnostic and biological materials, to improve the storage and the quality of DNA after extraction. Long-term maintenance of Penicillium species is essential for detailed studies. Fifty Penicillium species were isolated from different sources by direct and dilution method, and then preserved by spawn and lyophilization technique. Fungal isolates were purified and identified based on their morphology. The viability and purity of the fungal species by fungal spawn and lyophilized material (fungal spawn and fungal mat) were monitored immediately after storage at 1, 2 and 3 months at 4 oC. Each fungal isolate was considered viable if the rate of growth present was the same as that of the original culture and if the morphology of the colony matched the fungal identification documented for each species. All lyophilized Penicillium species were found viable at 1-3 months of storage recovered each time from both type of lyophilized material, fungal spawn and fungal mat and showed the initial colony characteristics and growth rates. Neither stabilizer nor skimmed milk was used in fungal material to protect it from sticking with the walls of the container. Modified method of Penicillium spawn preservation by lyoplilization has been found cost effective in contrast to liquid nitrogen preservation. It was concluded that lyophilization is simple, inexpensive, reliable and effective method for the long term preservation of Penicillium isolates.
Foliar Nutrition with Water Soluble Macro and Micro Nutrient Fertilizers for Yield Maximization in Bush Vegetable Cowpea
Authors: Krishnasree R.K. , Raj Sheeja K. , Pillai P. Shalini , Prathapan K. , Jacob D. , Beena R.
Published: November 2021

Background: Cowpea is a leguminous crop of indeterminate growth habit and continues to produce flowers throughout its life cycle. In order to realize the genetic yield potential of cowpea, nutrient requirements of later formed flushes also needs to be met. Hence the present study was formulated to assess the effect of foliar application of water-soluble macro nutrient fertilizers viz., NPK 19:19:19 and potassium nitrate and micronutrient fertilizers viz. zinc sulphate and solubor for yield maximization in bush vegetable cowpea. Methods: The field experiment was conducted at Coconut Research Station, Balaramapuram, during Rabi 2020-21. The experiment was laid out in randomized block design with 13 treatments in three replications. The treatments comprised of recommended dose of conventional fertilizers (RDF) NPK 20:30:10 kg ha-1 as control and RDF + foliar application of water-soluble fertilizers 19:19:19 (0.5%) and potassium nitrate (0.5%) with zinc sulphate (0.05%) and solubor (0.025%) in twelve different combinations. Result: Results revealed that compared to RDF alone, RDF + foliar application of water-soluble macro and micro nutrient fertilizers at 45 DAS significantly improved the dry matter production, number of pods per plant and pod weight and recorded a yield enhancement of 22 to 55 per cent. Among the treatments, RDF + foliar application of 19:19:19 (0.5%) and solubor (0.025%) at 45 DAS recorded the highest dry matter production per plant (39.51 g), pods per plant (30.88 no.), pod yield (7410 kg ha-1), net return (82651 Rs ha-1) and B:C ratio (2.26). The treatments, RDF + foliar application of 19:19:19 (0.5%) at 45 DAS; RDF + foliar application of 19:19:19 (0.5%), zinc sulphate (0.05%) and solubor (0.025%) at 45 DAS; and RDF + foliar application of potassium nitrate (0.5%) and solubor (0.025%) at 45 DAS also recorded comparable number of pods per plant, green pod yield, net return and B:C ratio. Considering the highest green pod yield, net return and B:C ratio, RDF + foliar application of NPK 19:19:19 (0.5%) and solubor (0.025%) at 45 DAS could be recommended for yield maximization in bush type vegetable cowpea.
Challenges Caused by the COVID-19 Quarantine for Families Raising Children with Disabilities: Compatibility Between Working from Home and Childcare
Authors: Gardziuleviciene Laura , Raisiene Agota Giedre
Published: November 2021

Parents with children having special needs go through extremely difficult emotional, psychological experiences and physical fatigue due to unavailability of help and lack of access to social services. The COVID-19 pandemic has worsened the situation since the need for cohesion and the importance of social responsibility were not addressed well by the public authorities. The unavailability of help is believed to have plunged parents even further into exclusion. If before the pandemic, parents felt stigmatized, the situation after the COVID-19 pandemic became significantly worse. Thus, with the help of the phenomenological research, we aimed to reveal the challenges faced by families raising children with disabilities in combining aspects of work and childcare, by analyzing the attitudes and experiences of the respondents. The study is relevant for both public authorities and parents raising children with special needs in the context of developing social inclusion and family support network respectively.
The Impact of Foreign Direct Investment on the Economic Growth of South Caucasus Countries
Authors: Scholer-Iordanashvil Lela
Published: November 2021

This paper focuses on the effects of foreign direct investment inflows on the economic growth in a panel of three South Caucasus countries using data from 1996-2019 periods. In this study, we applied the following control variables; trade openness, investment, real exchange rate, and population growth. Classical linear regression model was employed in this paper. Ordinary least squares methods are used for estimation. Empirical results revealed that there is no significant effect of FDI inflows on economic growth. The results show that inward FDI stock-to-GDP ratio and real GDP growth rate are positively correlated.
Liabilities and contingencies of Brazilian football clubs
Authors: De Oliveira Monique Cristiane , Borba José Alonso
Published: November 2021

This study aims to identify the characteristics of liabilities and contingencies of 20 clubs participating in the First and Second Division of the Brazilian Championship of 2017 that presented all financial statements from 2010 to 2018. It was found that 79 of 160 balance sheets analyzed presented uncovered liabilities and denoting effective problems of economic and financial unviability akthough no clubs broke effectively. The findings demonstrate that clubs cannot support themselves and eventually need to raise third-party resources. The study differs from previous research because it identifies the characteristics of liabilities, and provisions as present and future obligations for Brazilian football clubs. Thus, this research contributes by providing an overview of the indebtedness of Brazilian football clubs.
The Effect of CaO Catalyst Mass from Golden Snail Shell (Pomacea Canaliculata Lamarck) on Transesterification Reaction
Authors: Rahman Fachtur , Rodiah Siti
Published: November 2021

Biodiesel derived from waste encourages the development of environment-friendly alternative energy. One of the wastes that can be used as biodiesel is waste cooking oil. Biodiesel from waste cooking oil has some advantages such as non-toxic, less Carbon monoxide (CO), and environment-friendly. The produce of biodiesel from waste cooking oil was through transesterification reaction using CaO catalyst derived from golden snail shell. This study aimed to determine the optimum amount of catalyst that produced the highest yield. In this study, methanol was used as solvent by the molar ratio of methanol/waste cooking oil of 30:1, reaction temperature of 65˚C, reaction time for 2 hour, and variations of amount catalyst 3%, 5% and 7% by weight waste cooking oil. Biodiesel was analyzed by Gas Chromatography-Mass Spectroscopy showed that the highest yield achieved using 7% catalyst amounts was 93.28%.
EFEK INOVASI PENYINARAN LAMPU PADA USAHATANI BUAH NAGA DI DESA BULUREJO KECAMATAN PURWOHARJO KABUPATEN BANYUWANGI
Authors: Susanto Indra Dwi , Rondhi Mohammad
Published: November 2021

Dragon fruit is a type of cactus plant that is cultivated in Indonesia and is included in an annual plant because it can only bear fruit during the rainy season. One of the largest dragon fruit producing areas in Indonesia is located in Banyuwangi Regency, East Java. Bulurejo Village is the area that uses the most innovation in lighting lighting. The use of innovative light irradiation is able to develop dragon fruit plants so that dragon fruit plants can bear fruit outside the season. Research in Bulurejo Village, Purwoharjo District, Banyuwangi Regency aims: (1) To determine farming with the use of light illumination innovation in Bulurejo Village, Purwoharjo District, Banyuwangi Regency, (2) To determine the effect of innovative lighting effects on dragon fruit farming in Bulurejo Village, Purwoharjo District, Banyuwangi Regency . The determination of the research area was done purposively (purposive method). The research area used is Bulurejo Village, Purwoharjo District, Banyuwangi Regency. The sampling method in this study uses the determination of key informants using purposive sampling technique, which is selected with certain considerations and goals. The results showed that: (1) The existence of innovative lighting on dragon fruit plants in Bulurejo Village was well received by farmers and the community. The use of innovation in Bulurejo Village is able to increase the productivity of dragon fruit farmers to the maximum, (2) The effect of using light irradiation innovation on dragon fruit plants is very good for farmers economically as well as socially and culturally in the community. The increasing economic condition of dragon fruit farmers with large incomes has been able to increase the standard of living of farmers who were initially normal to become successful dragon fruit farmers. The social and cultural conditions of the community are also getting more harmonious after the innovation of lighting the lights.

Keywords: Dragon Fruit, Bulurejo Farmer, Lightning Innovation, Social Effect
Persepsi Petani Terhadap Kinerja Penyuluh Pertanian di Desa Torongrejo Kecamatan Junrejo Kota Batu
Authors: Feliyana Chindy , Ibrahim Jabal Tarik , Ningsih Gumoyo Mumpuni
Published: November 2021

Forest management carried out by the Panti District community in The performance of agricultural extension workers is starting to be felt by farmers, but in terms of farmers' perceptions of the performance of agricultural extension workers which are considered less than optimal because in the implementation of the extension there are obstacles such as differences in schedules between agricultural extension workers and farmer groups, many group members do not participate in extension activities. this. Regarding these obstacles, it is necessary to conduct a more in-depth study of farmers' perceptions of the performance of agricultural extension workers in Torongrejo Village, Junrejo District, Batu City. This study aims to analyze farmers' perceptions and the factors that influence farmers' perceptions of the performance of agricultural extension workers in Torongrejo Village, Junrejo District, Batu City. The technique of determining respondents in this study was simple random sampling. The number of respondents as many as 50 people is calculated based on the slovin formula. Data were collected by means of observation, interviews, questionnaires, and documentation. The analytical method used is Multiple Linear Regression with the help of SPSS (Software Program for Social Science) software. ). The ordinal scale data is converted to an interval scale with MSI (Methode of Successive Interval). Before the multiple linear regression analysis was tested, the classical assumption test, normality test, heteroscedasticity test and multicollinearity test were carried out. Based on the results of the analysis of the level of perception of farmers on the performance of the instructor as an initiator of 76%, as a motivator by 78%, as an educator by 78%, as a communicator by 79% and as a facilitator by 75% so that it can be said that the role that has been carried out by agricultural extension workers is categorized as good. The performance of agricultural instructors as initiators, motivators, educators, communicators and facilitators significantly influences the level of farmers' perceptions of the performance of agricultural extension workers.

Keywords : Perception, Farmer, Performance, Extension
Consumer learning behavior in adoption Tani Hub e-commerce
Authors: Rahmah Maulavida Qholbyah
Published: November 2021

As e-commerce develops in Indonesia, sales of fresh fruit and vegetable products move from physical stores to virtual markets through technological innovation. The adoption of e-commerce is marked by changes in purchasing behavior of fresh fruits and vegetables that originally relied on the senses, now mediated by a screen measuring at least 7 inches. Interaction between seller and buyer, or buyer with buyer also mediated. This condition does not require consumers to be able to see, hold and smell the product they want directly. When compared with conventional methods, the purchase of fresh vegetables and fruit through e-commerce has risks, namely uncertainty such as the physical quality of the product, taste or freshness. Consumers need knowledge and experience to reduce this uncertainty, where this knowledge and experience is obtained through a consumer learning process. This study describes the forms of consumer learning behavior starting from the beginning to get acquainted with adopting e-commerce. The research method used is qualitative with descriptive research type, and the method of data collection in the form of in-depth interviews with informants who are adopters of the Surabaya branch of the E-Commerce Tani Hub. This informant consists of a group of friends who have the same values, namely implementing a lifestyle and eating healthy food. The results of this study are in the form of learning behaviors shown by Tani Hub consumers through the process of information exchange with information sources that they consider credible, namely friendship circles and also primary information from the Tani Hub’ company itself.
Detection of Salmonella sp. on Bulk Meatballs and Packaged Meatballs at Sepanjang Market, Sidoarjo
Authors: Zain Rahmania , Hidanah Sri , Damayanti Ratna , Warsito Sunaryo Hadi
Published: November 2021

Background: Bacterial contamination in food can cause congenital diseases in the form of infections. Meatballs are one of the foods that are in demand by the public and foods that can be contaminated with salmonella bacteria. Detection of Salmonella sp bacteria can determine the quality of bulk meatballs and packaged meatballs. Salmonella sp bacteria should not contaminate the meatballs according to the quality requirements of the BSNI (Badan Standarisasi Nasional Indonesia). Purpose: To determine the contamination of Salmonella sp bacteria in bulk meatballs and packaged meatballs sold at Sepanjang market, Taman District, Sidoarjo Regency. Methods: The Salmonella sp. test on meatballs was carried out in four stages, pre-enrichment using Buffered Pepthone Water solution, enrichment using Tetrathionate Brothbase solution, isolation using Salmonella Shigella Agar media, and biochemical testing using Triple Sugar Iron Agar media. The samples used were 10 samples each. Result: The test proved that 20% of the samples were positively contaminated with Salmonella sp. both on bulk meatballs and on packaged meatballs. Conclusion: Food hygiene and sanitation must be applied properly and correctly in every process because food products circulating in public, especially meatball products, can avoid microbial contamination and be safe for consumption.
Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat
Authors: Weliyani Trima , Hamid Iwan Sahrial , Hidanah Sri , Prastiya Ragil Angga , Wibawati Prima Ayu
Published: November 2021

Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mice for 5 treatment groups: K+ (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) orally for 42 days. Histophatological scores were analyzed with Saphiro-Wilk Test and Anova. There is no effect of increasing testicular weight. 0,12 mg MSG can cause a decrease in the number of spermatogonia and spermatocytes. 0,2 mg robusta coffee extract can maintain the number of spermatogonia and spermatocytes.
Correlation of Reproduction Management on Losses of Dairy Farmers in Wagir District, Malang Regency
Authors: Ishaq Rizal Maulana , Suharsono Suharsono , Harijani Nenny , Hidanah Sri , Mustofa Imam
Published: November 2021

This study was conducted to find out how much losses the breeders get when their cattle experience a decline in day open (DO), service per conception (S/C), and calving interval (CI).There were 108 lactating dairy cows from the dairy farm, Wagir District, Malang Regency.The data that has been taken is then processed by analysis using linear regression method.The results of the analysis prove that reproductive management has an effect of 82% on farmer expenditure.For each setback DO per day, the farmer pays Rp. 609,05.Meanwhile, for each additional S/C the farmer pays Rp. 99,921.7.For each setback the farmer CI will incur a fee of IDR 228,54 / day.So that the equation found is expendses = 609,05 (DO) + 99,921.7 (s / c) +228,54 (CI).
Моделирование пространственно-временного распределения лекарственного агента в биологической ткани
Authors: Гиневский Алексей Феликсович , Ginevsky Alexey Feliksovich , Гиневский Дмитрий Алексеевич , Ginevsky Dmitrii Alekseevich , Ижевский Павел Владимирович , Izhevsky Pavel Vladimirovich
Published: November 2021

Предложена математическая модель фармакокинетики противоопухолевых препаратов, представляющая биологическую ткань в виде случайно-неоднородной среды. Модель базируется на системе уравнений реакции-диффузии, в которой коэффициенты являются случайными функциями пространства и времени. Коэффициенты модели вычисляются исходя из вероятности протекания процессов в живой
ткани. Показаны примеры применения предлагаемого подхода на двух препаратах:
«Цисплатин», используемый при химеотерапии рака, и «Бор-фенилаланин», предлагаемый как агент, повышающий дозу при облучении. Модель демонстрирует хорошее совпадение с результатами известных экспериментов. Описанный метод построения моделей фармакокинетики лекарственных препаратов может служить универсальным подходом для моделирования пространственно-временного распределения многих лекарств, в том числе использующих наночастицы. Результаты моделирования позволили предложить оптимизацию существующих протоколов химиотерапевтического и радиологического лечения.
Моделирование динамики низколетящего космического аппарата с прямоточным воздушным электрореактивным двигателем
Authors: Овчинников Михаил Юрьевич , Ovchinnikov Mikhail Yur'evich , Герман Анна Дмитриевна , Guerman Anna Dmitrievna , Маштаков Ярослав Владимирович , Mashtakov Yaroslav Vladimirovich , Ролдугин Дмитрий Сергеевич , Roldugin Dmitry Sergeevich
Published: November 2021

Проводится моделирование движения космического аппарата на сверхнизкой орбите высотой 175 км. Аппарат оснащен прямоточным воздушным электрореактивным двигателем, позволяющим компенсировать силу лобового сопротивления.
Проведено моделирование управляемого углового движения аппарата с учетом основных возмущающих факторов, включая ошибки в компоновке аппарата и установке двигателя, а также влияние ветра в атмосфере. Получена оценка энергопотребления системы управления в разных режимах движения.
Research of problems and prospects of state development in the pedagogical process
Authors: Kryshtanovych Myroslav , Romanova Alona , Koval Ihor , Lesko Nataliia , Lukashevska Ulyana
Published: November 2021

The purpose of the article is to analyze the features of the pedagogical process of problems and prospects for the development of state formation. The beginning of the third millennium is characterized by globalization of social development, rapprochement of nations, peoples, states, the transition of mankind from industrial to scientific and information technologies, high economic and technological systems, which are largely based on educational and intellectual potential. At the same time, the competition of regions, nations, states, and individual citizens is intensifying. State formation as a pedagogical process has common features and peculiarities for each country, people and society. Accordingly, state formation has its own characteristics. State formation is not just a process for the education system, but has the essential characteristics of the pedagogical and creative process, which absorbs an almost endless palette of conscious, unconscious and unconscious actions of the people and their elite. State formation is a historical process of state building, creation and development of its legal, political, economic, ideological, military, financial and other institutions and ensuring their functioning, which is extremely important in the modern education system. As a result, the main aspects of the pedagogical process of problems and prospects for the development of state formation were described
Identifikasi Percepatan Tanah Maksimum dan Intensitas Gempa Bumi di Sumatra Barat Menggunakan Metode Gutenberg-Richter
Authors: Hutasoit Erna Yustika , Dewi Ira Kusuma , Farid Faizar
Published: November 2021

Sumatra Barat memiliki tingkat kegempaan cukup tinggi karena berada pada zona Megathrust, Sesar Mentawai, dan Sesar Sumatra. Tingginya tingkat kegempaan ini mempengaruhi nilai percepatan tanah di Sumatra Barat yang merupakan parameter penting dalam perencanaan bangunan tahan gempa. Metode Gutenberg-Richter merupakan salah satu metode empiris untuk menghitung nilai percepatan tanah maksimum (PGA) dan intensitas gempa bumi berdasarkan magnitudo gempa. Data penelitian ialah data katalog gempa bumi dari BMKG dan USGS dengan periode 01 Januari 2005 hingga 15 September 2020 dengan magnitudo gempa Mb ≥3 dan kedalaman ≤70 km. Berdasarkan data BMKG diperoleh gempa bumi sebanyak 1136 kejadian dan menunjukkan nilai PGA di Sumatra Barat sekitar 0,16 – 1,44 m/s2 dengan intensitas V–VIII MMI serta episenter menyebar di zona akresi, zona Sesar Sumatra dan zona Sesar Mentawai. Sedangkan dari USGS diperoleh gempa bumi sebanyak 1140 kejadian dan menunjukkan nilai 0,28 – 1,35 m/s2 dengan intensitas VI–VIII MMI serta episenter yang menyebar di zona Sesar Mentawai. Berdasarkan analisis data baik dari BMKG maupun USGS diperoleh bahwa Kabupaten Kepulauan Mentawai adalah wilayah yang memiliki tingkat risiko gempa bumi paling tinggi dan berpotensi tsunami dengan nilai percepatan tanah maksimum sekitar 1,29 – 1,44 m/s2 dengan intensitas VIII MMI.
Pemanfaatan Frekuensi Alamiah Tanah Menggunakan Pengukuran Mikrotremor Tiga Komponen dalam Mendeteksi Kedalaman Batuan Dasar
Authors: Syamsuddin Erfan , Astuti Aulia Puji , Sofian Sofian , Aziz Dede Muhaimin , Habibullah Muhammad , Linggi Sindy Yustin
Published: November 2021

Suatu wilayah yang memiliki kondisi geologi yang sama dapat memberikan respon yang berbeda terhadap efek getaran tanah, bergantung pada karakteristik batuan penyusun formasi di wilayah itu. Fenomena ini disebut site effect. Spektra ambient noise yang diperoleh dari pengukuran mikrotremor dapat digunakan untuk menentukan respon suatu site khususnya frekuensi dominan lapisan sedimen. Respon frekuensi ini berhubungan dengan ketebalan lapisan sedimen. Berdasarkan formasi geologinya, Kota Palu tersusun atas endapan aluvium berumur holosen yang menjadi sedimen penyusun paling muda di wilayah tersebut. Penelitian ini bertujuan untuk memperoleh estimasi ketebalan lapisan sedimen di tiga titik pengukuran mikrotremor dari nilai spektrum horizontal to vertical () yang merempresentasi frekuensi dominan (f0) serta kecepatan gelombang geser (Vs) lapisan sedimen. Hasil yang diperoleh memperlihatkan nilai frekuensi dominan tanah f0 <2.5 Hz, hasil inversi kurva HVSR memperlihatkan variasi ketebalan sedimen (Vs < 750 m/s) antara 152 – 186 m yang mengindikasikan lapisan sedimen penyusunnya masuk dalam kategori tebal, sedangkan variasi nilai Vs30 berada antara rentang 291 – 381 m/s. Hasil penelitian ini dapat digunakan sebagai dasar acuan untuk tujuan geoteknik, seperti desain bangunan tahan gempabumi berdasarkan respon frekuensi dominan tanah serta kecepatan gelombang gesernya.
Analisis Karakteristik Arus di Perairan Teluk Parepare, Sulawesi Selatan
Authors: Ningsih Sri , Saka Bergita Gela M
Published: November 2021

Perairan Teluk Parepare merupakan teluk semi-tertutup, beberapa titik tertentu terdapat submarine canyon (kontur yang menjorok ke dalam) yang secara viskositas dinilai dapat mempengaruhi pola sirkulasi arus laut yakni vektor dan magnitude-nya. Penelitian ini bertujuan untuk mengetahui pola arus dan kecepatan arus pasang surut yang disebabkan oleh karakteristik kedalaman di perairan Parepare. Metode penelitian menggunakan analisis deskriptif kualitatif. Sementara analisis hidrodinamika menggunakan software SMS (Surface Water Modelling System) dengan sub-program RMA-2 yang diturunkan dari persamaan beda hingga 2D. Hasil penelitian menunjukkan bahwa kondisi perairan di Teluk Parepare pada waktu-waktu tertentu terjadi rotasi arus dan pertemuan arus yang disebabkan oleh variasi kedalaman dan adanya perubahan kecepatan. Perubahan dari kecepatan yang tinggi 0,068 – 0,21 m/s ke kecepatan yang cukup rendah 0,0029 – 0,0051 m/s. Pada daerah submarine canyon (kontur yang menjorok ke dalam), pola arus membentuk pusaran (turbulensi) dengan kecepatan rata-rata berkisar 0,031 m/s. Sehingga dapat dikatakan bahwa tipe kontur kedalaman dapat mempengaruhi pola arus di perairan Teluk Parepare. Karakteristik kondisi arus pada saat musim barat (hujan) kecepatan arus lebih besar dan lebih fluktuatif (tidak stabil) dibandingkan dengan kecepatan arus rata- rata pada musim timur (kemarau).
PENINGKATAN NILAI EKONOMIS DAN DAYA SAING PRODUK AGRARIS MELALUI PENDIDIKAN KREATIF BERBASIS MASYARAKAT DI KELURAHAN DELINGAN, KARANGANYAR
Authors: Febriansyah Muhamad Iqbal , Mufadilah A’la , Tathma Fathia Rizka , Sirojd Milati Jaisyul’usrah , Safiera Refiana Nafis , Aprilia Riska Fenoria , Rahmandani Suci Wahyu , Nashir Muhammad , Setyono Prabang , Himawan Widhi , Nancy Natasha
Published: November 2021

Kapasitas teknis pengolahan lanjut hasil panen menjadi sekat bagi upaya peningkatan ekonomi dan kesejahteraan petani. Kondisi tersebut ditemukan pula pada masyarakat tani pada lokasi pengabdian di Kelurahan Delingan, Karanganyar. Hal tersebut bersumber dari rendahnya tingkat kepedulian dan partisipasi warga dalam pendidikan formal maupun non formal, termasuk pada pendidikan usia dini dan remaja. Tujuan kegiatan pengabdian ini adalah melaksanakan peningkatan kapasitas pengolahan pertanian dan perekonomian masyarakat melalui pendidikan berbasis masyarakat. Metode yang digunakan dalam kegiatan pengabdian adalah : pendidikan berbasis masyarakat, metode difusi ipteks, dan workshop. Hasil kegiatan pengabdian ini berupa pelaksanaan  program kerja yang terdiri dari  : pembuatan pupuk kompos, penanaman bibit tanaman, penanaman tanaman hias dengan jelly warna – warni (hydrogel), dan pengolahan nugget sayuran, serta 2 program penunjang (forum belajar dan BTQ). Kesimpulan dari seluruh kegiatan ini adalah bahwa kegiatan tersebut telah terlaksana dengan baik namun perlu dilakukannya pengawasan secara langsung oleh pemerintah setempat agar warga tetap konsisten dalam membangun Kelurahan Delingan.  
Edukasi Diversifikasi Pangan Skala Rumah Tangga pada Masa Pandemi Bagi Masyarakat Di Lingkungan Kevikepan Daerah Istimewa Yogyakarta
Authors: Pangestika Leonie Margaretha Widya , Swasti Yuliana Reni , Pranata Fransiscus Sinung , Purwijantiningsih LM Ekawati
Published: November 2021

Selama masa pandemi, terjadi peningkatan aktivitas budidaya tanaman sayur mayur dan ikan lele yang dilakukan secara mandiri oleh masyarakat di lingkungan Kevikepan Daerah Istimewa Yogyakarta (DIY). Hal tersebut menyebabkan tingginya hasil panen di lingkup rumah tangga. Diversifikasi pangan menjadi solusi yang dapat dilakukan untuk mengolah hasil panen secara optimal, sehingga akan tercipta ketahanan pangan bagi masing-masing keluarga. Edukasi diversifikasi pangan bertujuan meningkatkan pengetahuan masyarakat terhadap ragam pangan yang dapat dikembangkan dengan mudah di rumah, serta trik teknologi pengolahan pangan tersebut. Edukasi berupa kegiatan penyuluhan dilakukan secara daring dan dihadiri 27 peserta yang merupakan masyarakat di lingkungan Kevikepan DIY. Teknik pengolahan produk pangan didemonstrasikan melalui video pengolahan sayuran hijau menjadi sayur fermentasi, cabai menjadi bubuk cabai, dan ikan lele menjadi sambal ikan lele. Tingkat pengetahuan peserta diukur melalui pengerjaan pretest dan post test berdasarkan pertanyaan yang sama. Hasil analisis uji Wilcoxon Signed Ranks membuktikan bahwa terdapat peningkatan skor yang signifikan setelah mengikuti kegiatan penyuluhan (p=0,004).
Management of Intracranial Pressure Control in Reciprocal Grade 3 Astrocytoma Patient In Dr. Moewardi General Hospital Surakarta: Case Report
Authors: Setijanto Eko , Wijaya Teddy
Published: November 2021

Surgery in patients with astrocytoma is performed based on the size of the tumor in the brain and the functional status of the patients. Management of patients with intracranial hypertension can be guided by monitoring intracranial pressure (ICP) perioperatively. A variety of ventricular, intraparenchymal, and subdural equipment can be installed by neurosurgeons to provide ICP measurements.

We reported a 50-year-old female patient, with a complaint of having a speech disorder since four years ago. Preoperative physical examination showed GCS E4V5M6, patient's body mass index was 29.29 kg/m2 (obese). Patient’s physical status was assessed with ASA 3. There was no significant abnormality in laboratory examination. MRI Brain contrast examination showed solid cystic lesion in supratentorial left temporal lobe with size 2.3x3.5x4.7cm accompanied by broad perifocal edema in the left frontal, temporal and parietal lobe. The chest X-ray showed cardiomegaly and pneumonia. Electrocardiography showed normal sinus rhythm.

Craniotomy in patients with astrocytoma is performed based on the size of the tumor in the brain and the functional status of the patient. Preoperative evaluation for patients undergoing craniotomy should be carried out to determine the presence or absence of intracranial hypertension. In principle, postoperative management in the ICU is to control the respiratory system, optimize the cardiovascular system, and prevent possible complications.

Management of intracranial pressure control in reciprocal grade 3 astrocytoma patient should be paid attention to various things and consider the condition of the patients. Preoperative preparations, as well as perioperative and postoperative monitoring, should be carefully observed to prevent complications that will adversely affect patients.

 
Perioperative Management of Subdural Hemorrhage (SDH) Trepanation Decompression with Hemophilia A
Authors: Praniarda Andika Satria , Laksono Buyung Hartiyo
Published: November 2021

Hemophilia is a serious inherited blood disease, transmitted by women, that affects mainly men and lasts for a lifetime. Hemophilia A is the most common form. If any of the factors necessary for blood clotting are absent or insufficient, the clotting mechanism is disturbed, causing insatiable bleeding. The most common cause of death in hemophilia patients is cerebral hemorrhage due to head trauma. In cases of intracranial hemorrhage, surgery should be performed immediately to obtain a better prognosis. A 17-year-old man diagnosed with a 2x4 loss of consciousness due to intracranial subdural hemorrhage (SDH) in the left frontotemporoparietal region and cerebral edema on day 4 accompanied by subfalcine herniation to the right with hemophilia A, planned trepanation decompression for SDH evacuation. The patient received 4000 units of factor VIII injection before surgery. Bleeding during surgery was 1100cc and he received a transfusion of 1940cc blood products until hemodynamically stable. In the postoperative phase, he was admitted to the ICU for 8 days, extubation was performed after the condition improved. In patient with hemophilia, evacuation of bleeding should be performed immediately, but there is a high risk of rebleeding. A recombinant factor VIII substitute should be administered immediately for the treatment of acute bleeding in patients with severe haemophilia A. Anesthetic maintenance should include reducing the risk of hypertension and tachycardia to minimize bleeding.
Perioperative Management in Parturient with Severe Preeclampsia, Obesity, and COVID-19
Authors: Yudhistira Rafael Bagus , Yudhistira Muhammad Yurizar , Supraptomo Raden Theodorus
Published: November 2021

The elevated cases of pregnant women infected with COVID-19 who needed to undergo caesarean section is a great challenge to anesthesiologists. Morbid obesity and preeclampsia in pregnancy are also another challenge to medical practice especially when the patient requires caesarean section. To describe the perioperative management of a morbidly obese preeclamptic patient with COVID-19. A pregnant woman with mild case of COVID-19, severe preeclampsia and obesity underwent an emergency caesarean section. Spinal anesthesia was performed using a Whitacre 26G spinal needle with 76 mm length, bupivacaine 0.5% 12.5 mg as spinal anesthesia agent and fentanyl 25 mcg as adjuvant. All operating teams use PPE according to COVID-19 guidelines and standard procedures. The operation went with a good outcome without any transmission to the operating team. The patient underwent treatment without postoperative complications. Spinal anesthesia is considered safe to be a usual technique for parturient with preeclampsia and morbid obesity. A proper COVID-19 surgery protocol is crucial in order to protect health workers handling COVID-19 patients.
Coronary Heart Disease: Diagnosis and Therapy
Authors: Mahmuda Iin Novita Nurhudayati , Nurkusumasari Nanda , Nofaldi Fakhri , Astuti Prihatin Puji , Syafitri Ferika Dian , Dessy Dessy
Published: November 2021

Coronary heart disease (CHD), is one of the non-communicable diseases that has a tendency to increase every year and have an impact not only on developed countries, but also in developing countries. According to the World Health Organization (WHO), in 2012 there were 56 million deaths worldwide caused by non-communicable disease and heart disease contributed 46.2% or caused 17.5 million deaths. This review article to give brief explanation about CHD from risk factors, diagnosed criteria, management therapy and prognosis. Risk factors for CHD can be distinguished into major risk factors and minor risk factors. Symptoms of CHD are discomfort in the chest ranging from pain crushed during activity and improved with rest to continuous chest pain. The diagnosis of CHD is established based on anamnesis, physical examination, and laboratory examination. The CHD classification consists  of Stable Angina Pectoris (APS) and Acute Coronary Syndrome (ACS). Lifestyle changes accompanied by right medication can reduce complications caused             by CHD.
Model pengentasan kemiskinan melalui peran financial inclusion di Indonesia
Authors: Anindyntha Firdha Aksari , Susilowati Dwi , Kurniawati Eris Tri
Published: November 2021

The poverty rate in Indonesia is quite high compared to other Asean countries. Indonesia has a poverty rate of 9.8% higher than Thailand and Malaysia. The financial sector through financial inclusion is an alternative policy implemented by the government as an effort to relieve poverty in Indonesia. The fact in Indonesia there is still quite a lot of people who have not been able to access financial services, especially banking sector. This study aims to determine the model of poverty alleviation through the role of financial inclusion in Indonesia. The data analysis technique used PLS-SEM. The results showed that two of three financial inclusion variables, namely access and usage had a significant negative effect on poverty, which means when the role of financial inclusion in Indonesia increases can reduce the poverty in Indonesia. Access variable has a negative effect on poverty which means that increasing public access to debit card ownership, bank accounts, and e-money cards can reduce poverty in Indonesia. Usage variable has a negative effect on poverty which means the increasing use of financial services as reflected with the volume of debit transactions and credit transactions, it can reduce poverty in Indonesia.
Pengaruh city branding dan electronic word of mouth terhadap kunjungan wisatawan di Kabupaten Banyuwangi
Authors: Muslim Shohib , Hidayati Nur , Pardiman Pardiman
Published: November 2021

This study aims to examine the effect of city branding and electronic word of mouth on the decision to visit Banyuwangi based on the tagline sunrise of java. This research was conducted on the millennial generation in Indonesia. This type of research is explanatory research using a quantitative approach. The data used are primary data obtained based on the results of online questionnaire data from 160 respondents. Sampling using purposive sampling technique with the criteria of respondents having visited at least one tourist destination in Banyuwangi and actively using social media.  The results showed that city branding and electronic word of mouth had a positive effect on the decision to visit. Electronic word of mouth has the most dominant influence on visiting decisions compared to city branding. Based on the results of the analysis show that this study provides a theoretical contribution to the factors that influence the decision to visit for tourists, namely city branding and electronic word of mouth. This research also makes a practical contribution in developing strategies to improve visiting decisions.