bluuebunny/crossref_metadata_2025 huggingface dataset:
CUT&Tag-direct for whole cells with CUTAC v2
Authors: Henikoff Steven , Henikoff Jorja , Ahmad Kami
Published: December 2024

We previously introduced Cleavage Under Targets & Tagmentation (CUT&Tag), an epigenomic profiling method in which antibody tethering of the Tn5 transposase to a chromatin epitope of interest maps specific chromatin features in small samples and single cells.With CUT&Tag, intact cells or nuclei are permeabilized, followed by successive addition of a primary antibody, a secondary antibody, and a chimeric Protein A-Transposase fusion protein that binds to the antibody. Addition of Mg++ activates the transposase and inserts sequencing adapters into adjacent DNAin situ.We have since adapted CUT&Tag to also map chromatin accessibility by simply modifying thetransposaseactivation conditions when using histone H3K4me2, H3K4me3 or Serine-5-phosphorylated RNA Polymerase II antibodies. Using these antibodies, tagmentation of accessible DNA sites is redirected to produce chromatin accessibility maps with exceptionally high signal-to-noise and resolution. All steps from nuclei to amplified sequencing-ready libraries are performed in single PCR tubeswith non-toxic reagents using inexpensive equipment, making our simplified strategy for simultaneous chromatin profiling and accessibility mapping suitable for the lab, home workbench or classroom. New with this version are mostly corrections and minor improvements, including an optional pre-PCR tube transfer step for higher cell numbers.
AN ISOTOPY EXTENSION ON OPEN MANIFOLDS
Authors: Cardim Nancy de Souza , Silva Mário Olivero Marques da
Published: December 2024

Let be a compact topological manifold of , with connected boundary . Let be the simplicial group of homeomorphisms and denote the interior of by Int . Let Int be the restriction map and let be the homotopy fiber of over the . We proved that is isomorphic to , where is the concordance space of .
FOLDING MOTION IN THAT SHRINKS A GOOD POLYGONAL ANNULUS TO ARBITRARY SMALL NEIGHBORHOOD OF THE INNER BOUNDARY
Authors: Murai Hiroko
Published: December 2024

In 2004, Demaine et al. showed that if is a simply connected polygonal region in the plane, then for any piecewise- folded state of , there exists a folding motion from to [1]. We have shown that if is not simply connected, then the conclusion of the theorem does not necessarily hold, in fact, there exists an annulus in such that there exists a piecewise- folded state of which does not admit folding motions from by using "knot and link theory". From the viewpoint of knot and link theory, it is reasonable to expect that the folded state admits a folding motion from if and only if forms a trivial link in (Conjecture). Note that the 'only if part of the Conjecture is obvious. In this paper, we give a proof of the following statement that will be used in an expected proof of the 'if part of the Conjecture for special kind of annulus

.

If
is an annulus such that each of the boundary components bounds a polygonal convex region, then for any , there exists a flat folded state such that is contained in the -neighborhood of the inner boundary of in , denoted by with a strongly flat folding motion from to which satisfies the following:
(1) For any , the number of 1 -simplices of the 1 -complex is finite, where denotes the canonical crease pattern of .
(2) For any is a good polygonal annulus.
(3) For any with , we have .
Mizah Teorilerine Göre Ortaokul Türkçe Ders Kitaplarındaki Metinlerin İncelenmesi
Authors: Durukoğlu Salim , Kaçmaz Gökçe
Published: December 2024

Bu çalışma ile ortaokul 5, 6, 7 ve 8. sınıf Türkçe ders kitaplarında bulunan mizahi metinlerin ve mizah unsurlarının, mizah teorilerine göre açıklanarak kuramsal özelliklerinin belirlenmesi amaçlanmıştır. Bu amaç doğrultusunda verilerin toplanmasında, nitel araştırma modellerinden olan doküman incelenmesinden yararlanılmıştır. Ortaokul Türkçe ders kitapları içerisinden en çok tercih edilen yayınevlerine ait dört ders kitabı incelenmiştir. Araştırma sırasında her sınıf düzeyindeki Türkçe ders kitabında yer alan mizahi metinler ve mizah unsurları, alan uzmanları tarafından en çok tercih edilen uyumsuzluk, kavrama ve rahatlama kuramları ile Morreal ve Henri Bergson’a ait çağdaş mizah kuramlarına göre incelenmiştir. Araştırma sonucunda elde edilen veriler, nitel veri analiz tekniklerinden betimsel analiz tekniğiyle çözümlenmiştir. Türkçe ders kitaplarında doğrudan mizah unsurları olarak Nasreddin Hoca fıkraları ile diğer fıkralar, karikatürler ile Karagöz ve Hacivat metinleri yer almaktadır. Bu metin ve ögelerin azlığı nedeniyle diğer konu ve temalardaki tüm metinler de araştırmaya dahil edilmiş, inceleme sonucunda ders kitaplarında yer alan 160 metinden yedisinin üstünlük kuramı, 10’unun uyumsuzluk ve kavrama kuramı, 4’ünün rahatlama kuramı, 10’unun çağdaş mizah kuramları ile ilişkili olduğu saptanmıştır. Bu saptama sonucunda Türkçe ders kitapları içerisinde yer alan metin sayıları da göz önüne alındığında, ders kitaplarında genel anlamda yeterli sayı, içerik ve nitelikte mizahi unsur bulunmadığı görülmüştür.
Physicochemical properties of activated carbon modified with 2-phenylpropene
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, DIYUK Vitaliy
Published: December 2024

Introduction. Application of porous carbon materials in various adsorption-catalytic and electrochemical processes requires optimization of their structural-sorption parameters and chemical properties of the surface layer. Modification of the surface of carbon materials with heteroatoms allows to significantly change its acid-base and hydrophilic-hydrophobic properties, which significantly expands the limits of application. A promising method of increasing the reactivity of the surface of carbon materials is the preparation of precursor materials that contain highly specific centers capable of further modification and preservation of the developed porous structure. This work is devoted to the study of the functionalization of the carbon surface with 2-phenylpropene (РhP) and to the study of its physicochemical properties and reactivity.

Methods. Activated carbon was modified with 2-phenylpropene followed by its (oligo)polymerization and sulfonated with oleum. The surface morphology of the samples was studied by scanning electron microscopy (SEM), the specific surface area and the total pore volume were determined by the method of low-temperature nitrogen adsorption-desorption. The concentration of surface acid centers was determined by the titrimetric method. The thermal stability of the surface layer and the content of applied РhP in the modified samples were investigated by thermogravimetric analysis (TGA). The mechanisms of decomposition of the surface layer of the modified samples were studied by the method of thermoprogrammed desorption mass spectrometry (TPD-MS). The catalytic activity of the samples was studied in the model reaction of gas-phase dehydration of propan-2-ol.

Results. Modification of activated carbon with 2-phenylpropene, followed by its (oligo)polymerization, is an effective method of increasing the concentration of active surface centers. This method allows introducing up to 0.77 mmol/g of thermally stable forms of РhP, capable of further sulfonation, into the surface layer of activated carbon. Studies of nitrogen adsorption-desorption demonstrate moderate changes in the specific surface area and porosity of activated carbon with the preservation of significant adsorption capacity. The methods of thermogravimetric analysis and thermoprogrammed desorption proved the high thermal stability of applied forms of 2-phenylpropene in the temperature range of 30–230 °С. Sulfated samples contain up to 0.72 mmol/g of strongly acidic SO3H groups and can be used as heterogeneous acid-base catalysts.

Conclusions. Modification of activated carbon activated carbon with 2-phenylpropene followed by its (oligo)polymerization is an effective method of increasing the concentration of active surface centers and obtaining heterogeneous acid-base catalysts containing up to 0.72 mmol/g of strongly acidic SO3H groups.
The possibility of effective using the conservative and the minimally invasive treatment methods at various stages of the Dupuytren disease
Authors: Ovchinnikova Ekaterina K. , Gilfanov Sergey I.
Published: December 2024

A literature review is presented on the conservative and minimally invasive methods of treating the Dupuytren contracture. The investigators discuss both the methods implemented into clinical practice and those, which are currently at the stage of clinical and laboratory trials, including the minimally invasive methods, which can be used not only at the later stages, but also in cases of early manifestations of the disease. Among them there are the combined use of conservative methods, the radiation therapy, the injections of collagenase and steroids, the use of immunodepressive medicines and the needle aponeurotomy. These methods can be used at the earliest stages of the disease, however, the absence of proper evidence base often hinders their wide implementation. Up to the present moment, there is no commonly acknowledged approach to managing and treating the patients with early stage of the disease. The modern approach is focused on the invasive treatment of only later disease stages and of the severe contracture cases. This is why we would like to emphasize the potential of minimally invasive methods at the early stages of the Dupuytren disease, as well as the necessity of further research in this direction along with the importance of implementing such methods into everyday practice of the physicians.
Vitral assessment of mast cells degranulation mediated by IgG antibodies
Authors: Mamontov Andrey S. , Kutukova Nadezhda A. , Desheva Yulia A. , Polevshchikov Alexander V.
Published: December 2024

BACKGROUND: Data on the potential for mast cell activation and degranulation under these IgG-containing immune complexes indicate the presence of another innovative pathway for mast cell activation and help explain the severe infection following vaccination.
AIM: The aim of the study was to evaluate the possibility of activation and degranulation of mast cells of peritoneal exudate in mice by binding Fcγ receptors.
MATERIALS AND METHODS: Influenza viruses A/Vietnam/1194/2004(H5N1) NIBRG-14 and A/New York/61/ 2015(H1N1)pdm09 were used in the work. Cells of the peritoneal exudate of CBA mice, containing an average of 7–10% mast cells, were used as a source of mast cells. The degranulation of mast cells 40 min after the introduction of IgG-containing immune complexes into cultures was assessed by the release of histamine into culture attachments. The histamine level was determined fluorimetrically after the formation of its complexes with orthophthalic aldehyde, and the histamine concentration was expressed in ng/ml.
RESULTS: In response to the binding of Fcγ receptors, a dose-dependent release of histamine from the mast cells occurs. Histamine production was noted both during the introduction of model immune complexes formed by thermally aggregated IgG, and during the formation of complexes including IgG and influenza viruses of different strains. A higher level of histamine secretion was noted during the formation of IgG complexes with the H5N1 influenza virus. The level of histamine mast cells production during Fcγ receptor binding was comparable to the response to Fcε receptor binding.
CONCLUSIONS: Binding of immune complexes containing IgG class immunoglobulins to receptors on the surface of peritoneal exudate mast cells leads to their activation and degranulation, which is accompanied by dose-dependent histamine secretion, the level of which also depends on the strain of influenza virus in the complex.
Role of the intestinal microbiota in the pathogenesis of multiple sclerosis. Part 3. Gut microbiota as a potential trigger for multiple sclerosis
Authors: Abdurasulova Irina N.
Published: December 2024

The previous part of the review examined the role of the intestinal microbiota as a susceptibility factor to multiple sclerosis. This part of the review provides facts that confirm the trigger role of intestinal microbiota. The main attention is paid to the initial stages of pathogenesis, which, according to the modern concept of multiple sclerosis, occur in the gastrointestinal tract.
Assessment of early complications of antitumor treatment of rectal cancer using the International Classification of Functioning
Authors: Khan Esmira A. , Turovinina Elena F.
Published: December 2024

Rehabilitation of cancer patients and minimizing the complications of antitumor treatment are important modern goals with significant medical, social and economic implications. The development of complications following complex treatment of colorectal cancer depends on the patient’s comorbidities, such predisposing factors as pelvic floor muscle weakness, preoperative treatment, surgical extent, and a multidisciplinary approach from the moment of diagnosis of a malignant neoplasm and preparation for every stage of special treatment. As a result of analysis using the International Classification of Functioning, leading structural disorders were identified in the early postoperative period: qualitative changes in the structure of the large intestine, gastrointestinal continuity disruption with terminal transversostomy (s 5401.3), qualitative changes in the bladder structure, violation of integrity with defect suturing and epicystostomy removal (s 6102.3), qualitative changes in the pelvic floor structure, consequences of advanced surgery on the rectum, and repeated surgery (s 620.2). Functional impairments included moderate disturbances in night sleep (b 134.2), tenderness around the postoperative scar (b 280.2), body image perception (b 1800.2), tactile sensitivity (b 2702), peristomal skin sensations (b 840.2), and bloating (b 5351.2). Three-point rating was attributed to severe disorders in bowel movements frequency (b 5252.3), urination (b 6200.3), and bowel movements regulation (d 5301.3). When assessing “activity and participation,” changes were observed in coping with stress (d 2401.2), and regulating bowel movements (d 5301.3) and urination (d 5300.3). Positive aspects were identified when assessing the patient’s environment, their social status (family and immediate relatives, e 310.+2). The peristomal area was assessed, and individualized technical rehabilitation aids were selected (products and training technologies, e 300.+3).
Satisfaction assessment of people with disabilities by comprehensive outpatient rehabilitation assistance
Authors: Korneva Natalia V. , Bozhkov Igor A. , Silidi Ilia Yu. , Goryainov Igor V. , Sterlikov Sergey A.
Published: December 2024

BACKGROUND: The implementation of a set of rehabilitation measures, in accordance with the Individual Rehabilitation and Habilitation Program (IRHP), is a key task for outpatient medical and social organizations. Satisfaction of disabled people with the rehabilitation care they receive depends on the alignment between expected and received services. The study addresses the need to assess the adequacy of the comprehensive rehabilitation efforts and satisfaction among people with disabilities resulting from the progression of socially significant diseases.
AIM: To assess the satisfaction of disabled people with socially significant diseases regarding rehabilitation measures carried out in outpatient settings in accordance with the IPHP.
MATERIALS AND METHODS: From September to December 2023, a sociological survey was conducted at the city polyclinics of the Kalininsky administrative district of St. Petersburg (polyclinics 86, 54, 96, 112, and 118). The survey included 384 respondents, comprising disabled people and legal representatives of disabled children with socially significant diseases.
RESULTS: The study revealed low satisfaction levels, with only 58.1% of respondents fully satisfied with the rehabilitation measures, and 41.1% reporting they did not receive complete rehabilitation assistance for disabled people with socially significant diseases. An association was established between the subjective assessment of the rehabilitation effectiveness by disabled people and their health self-assessment according on the EQ-VAS scale (p=0.001). Among respondents with low health self-assessment according to the EQ-VAS scale, social and environmental adaptation measures were in highest demand (p=0.04). Coverage of health resort treatment was limited to 21%, with the primary barrier being difficulties with travel to the treatment site in 65.3% of cases, and the treatment had no significant impact on health self-assessment.
CONCLUSION: Low coverage of comprehensive medical and social rehabilitation care at the outpatient level negatively affects the satisfaction and subjective health assessment of disabled people in dynamics. Regular monitoring of the needs of disabled people and assessing satisfaction with rehabilitation care provided both in medical institutions and in social service organizations are essential for enhancing interdepartmental collaboration and making effective organizational decisions.
Indicators of primary and recurrent disability due to occupational injuries in Kemerovo Territory — Kuzbass in dynamics for 2016–2023
Authors: Gavrilyuk Olga N.
Published: December 2024

BACKGROUND: Comprehensive rehabilitation and habilitation in Russia are undergoing a transformation stage, with a focus on the biopsychosocial approach that emphasizes planned rehabilitation activities and evaluation of outcomes. In Kuzbass, the incidence of occupational injuries leading to disability is higher than the national average, which requires studying the need for professional and social rehabilitation measures for those affected by work-related injuries.
AIM: To study the structure of primary and recurrent disability due to occupational injuries with regard to age and severity of disability groups in Kuzbass over an 8-year period (2016–2023).
MATERIALS AND METHODS: A retrospective cohort study was conducted on adults in Kuzbass who were newly or repeatedly recognized as disabled due to occupational injuries over 8 years (2016–2023). Quantitative data were analyzed using absolute values, percentages, and intensive indicators. The general trend in disability dynamics was identified using a moving average method, supplemented by statistical, analytical, and expert judgment techniques.
RESULTS: The total disability resulting from occupational injuries comprised 486 primary cases (25% individuals) and 1,466 recurrent cases (75% individuals). The average annual rate of primary disability in 2016–2023 was 61 individuals, while the rate of recurrent disability for this 8-year period averaged 183 individuals per year. Young adults and middle-aged individuals of working age prevailed in the structure of disability by age for the entire period of observation, and the majority was classified under disability Group III.
CONCLUSION: The prevalence of young adults and middle-aged individuals, as well as the disability Group III, allows for active planning and implementation of comprehensive rehabilitation measures to restore the professional and social status of those injured at work. Rehabilitation prognosis is usually favorable, and the potential is high.
Does Corporate Governance Affect Thriving at Work? Employees' Roles in Knowledge Sharing and Prosocial Motivation
Authors: Tarsuslu Sinan
Published: December 2024

This study examines the mediating role of knowledge sharing and the moderating role of prosocial motivation in the effect of nurses’ perceptions of corporate governance on thriving at work. For this purpose, corporate governance, thriving at work, knowledge sharing and prosocial motivation scales were used in the study. The population of the study consists of 319 nurses out of 668 working in the training and research hospital and state hospital located in Erzincan city centre and conducting their activities according to the affiliation regulation. In addition, the research was designed in descriptive-relational mediator type. In the study analysis, the AMOS 23 application was used to verify the scale factors and SPSS PROCESS MACRO model 14 was used in the analysis of variables to evaluate the mediating and moderating role of the study. According to the results of the research, there is a significant and positive relationship between corporate governance and thriving at work, knowledge sharing and prosocial motivation at work. In addition, it was determined that knowledge sharing has a mediating role in the effect of corporate governance perception on thriving at work and prosocial motivation has a moderating role in the indirect effect of corporate governance (through knowledge sharing) on thriving at work. Ultimately, this research is important in terms of contributing to a better understanding of the complex relationship between corporate governance and employee behaviour. Especially for organisations in developing countries such as Turkey, the findings and recommendations of the research may also help to develop more effective human resource management practices.
Terrorist Events and Foreign Direct Investment: Outcomes Unveiled by Robust Statistical Models in the Example of Greece
Authors: Terzi Mahir , Yenal Serkan
Published: December 2024

This study examines whether the terrorist attacks impact foreign direct investments to Greece, with as much up-to-date data as possible. In this framework, hypotheses are tested within the framework of relational models through the data between 1970 and 2020. The results show a medium correlation between terrorist attacks and foreign direct investment, which is statistically significant. There is also a slightly higher correlation between terrorist attacks and foreign direct investment as a parameter of gross domestic product, which is statistically significant. Moreover, as the robust regression analysis shows, there is a bidirectional causal relationship between the variables. However, with complete data, there appears to be a causality tendency between variables by increasing foreign direct investment in the short term. At the same time, the results reveal causality from foreign direct investment to terrorist attacks.
SEMI-SUPERVISED CLASSIFICATION OF 2D MATERIALS USING SELF-TRAINING CONVOLUTIONAL NEURAL NETWORKS
Authors: Perkgöz Cahit , Kavaklı Umut Kaan , Görgün Bahar , Terzi Ayşegül
Published: December 2024

Deep learning algorithms require large amounts of data, and their accuracy rates are directly related to the amount and quality of the data. Moreover, supervised learning models require the data to be labeled. However, data labeling is always a time-consuming and laborious process. Labeling data obtained from microscope images can be more laborious. Molybdenum disulfide (MoS2) in monolayer form, which can be produced on large surfaces with the chemical vapor deposition method (CVD) and has advantages for potential electronic applications, is a frequently studied material in the field of nanotechnology. However, MoS2 produced on these large surfaces usually has defective surfaces and needs to be detected. This process is a difficult process to be performed with a microscope by an expert. Artificial intelligence-based supervised learning algorithms, which need labeled data, provide an effective solution for these detections. Furthermore, increasing the number of labeled data increases the accuracy of these algorithms.

In this study, a teacher-student model is explored using self-training, a semi-supervised learning technique, to effectively train a deep convolutional neural network to detect defects on MoS2 samples. Initially, the teacher model is trained using a small amount of data labeled by an expert. This trained model is enriched by generating pseudo-labels for previously unlabeled data. Then, a student model is trained using these real and pseudo-labeled data. The trained model then replaces the teacher model, and the process repeats, gradually improving labeling accuracy. The results show that the self-training method increases accuracy from 77% to 82% compared to the CNN model trained only on the existing labeled data, and the defect regions in MoS2 are effectively classified with minimal manual labeling.
Chronobiotics: classifications of existing circadian clock modulators, future perspectives
Authors: Solovev I.A. , Golubev D.A.
Published: December 2024

The review summarizes recent achievements and future prospects in the use of chronobiotics for regulating circadian rhythms regulation. Special attention is paid to the mechanisms' action, their classification, and the impact of chemical interventions on the biological clock. Chronobiotics defined as a diverse group of compounds capable of restoring disrupted circadian functions, addressing challenges such as irregular work schedules, artificial light exposure or ageing. The review categorizes these compounds by their pharmacological effects, molecular targets, and chemical structures, underlining their ability to enhance or inhibit key circadian components like CLOCK, BMAL1, PER, and CRY. A particular focus is placed on the therapeutic applications of chronobiotics, including their potential for treating sleep disorders, metabolic issues, and age-related rhythm disturbances, underscoring their wide-ranging applicability in health care. Chronobiotic compounds have promising roles in maintaining physiological rhythms, supporting healthy aging, and enhancing personalised health care. Given their diverse therapeutic potential, chronobiotics are positioned as a significant avenue for further clinical application, marking them as a crucial area of ongoing research and innovation.
Personalization of a computational systems biology model of blood platelet calcium signaling
Authors: Balabin F.A. , Korobkina J.D.D. , Galkina S.V. , Panteleev M.A. , Sveshnikova A.N.
Published: December 2024

Anuclear blood cells, platelets, are the basis for the formation of blood clots in human vessels. While antiplatelet therapy is most often used after ischemic events, there is a need for its personalization due to the limited effectiveness and risks of bleeding. Previously, we developed a series of computational models to describe intracellular platelet signaling and a set of experimental methods to characterize the platelets of a given patient. To build a personalized model of platelet signaling, we also conducted research on platelet proteomics. The aim of this study was to personalize the central module of intracellular platelet signaling responsible for the formation of calcium oscillations in response to activation. The model consists of 26 ordinary differential equations. To personalize the model, proteomics data were used and unknown model parameters were selected based on experimental data on the shape and frequency of calcium oscillations in single platelets. As a result of the study, it has been shown that the key personalized parameters of the platelet oscillatory response are the degree of asymmetry of a single calcium spike and the maximum frequency of oscillations. Based on the listed experimentally determined parameters and proteomics data, an algorithm for personalization of the model has been proposed. Here we considered three healthy pediatric donors of different ages. Based on the models, personal curves of platelet calcium response to activation were obtained. The analysis of the models has shown that while there is a large heterogeneity of individual indicators of intracellular signaling, such as the activity of calcium pumps (SERCA) and inositoltriphosphate (IP₃) receptors (IP₃R), these indicators compensate each other in each donors. This observation is confirmed by the analysis of proteomics data from 15 healthy patients: this analysis demonstrates a correlation between the total amount of SERCA and IP₃R. Thus, several new features of human platelet calcium signaling are shown and an algorithm for personalizing its model is proposed.
Homology modeling of the orthoflavivirus NS1 protein for virtual screening of potential ligands
Authors: Fomina A.D. , Palyulin V.A. , Osolodkin D.I.
Published: December 2024

The orthoflavivirus NS1 protein is a relatively understudied target for the design of broad-spectrum anti-orthoflaviviral drugs. Currently, the NS1 protein structures of tick-borne orthoflaviviruses have not been published yet, but these structures can be modelled by homology, thus generating a large amount of structural data. We performed homology modelling of the NS1 protein structures of epidemiologically significant orthoflaviviruses and analysed the possibility of using these models in ensemble docking-based virtual screening. The limitations of the method and the importance of separating the models based on the vector organism when selecting an ensemble have been demonstrated.
Gaya Komunikasi Interpersonal Guru Terhadap Keterlibatan Siswa Berkebutuhan Khusus di Sekolah Luar Biasa Negeri Jenangan
Authors: Puspahati Destya Cantika , Oki Cahyo Nugroho  , Deny Wahyu Tricana
Published: December 2024

Semua anak memiliki hak untuk menempuh pendidikan disekolah, termasuk anak berkebutuhan khusus. Guru sebagai informan yang baik adalah kunci dari keberhasilan siswanya memahami pesan yang disampaikan. Banyak kegagalan penyampaian pesan yang disebabkan oleh ketidak sesuaian gaya komunikasi antar guru terhadap siswanya. Jika, guru mempunyai gaya komunikasi yang tepat maka pesan yang disampaikan kepada siswa akan mudah dipahami dan tentu mempengaruhi cara pemahaman pesan oleh siswanya. Komunikasi interpersonal yang dikaitkan dengan gaya komunikasi juga menjadi kunci efektifitas dalam mencapai keberhasilan komunikasi. Penelitian ini bertujuan untuk mengetahui bagaimana gaya komunikasi interpersonal guru terhadap siswa berkebutuhan khusus di Sekolah Luar Biasa Negeri Jenangan. Peneliti menggunakan motode penelitian deskriptif kualitatif dengan melakukan wawancara pada guru Sekolah Luar Biasa Negeri Jenangan. Untuk memahami gaya komunikasi dominan pada guru maka peneliti menggunakan teori gaya komunikasi Norton yang meliputi 10 gaya komunikasi. Hasil penelitian ini menunjukkan bahwa gaya komunikasi interpesonal guru dengan penggunaan komunikasi verbal dan nonverbal yang disesuai kan dengan kebutuhann siswa. Hambatan dalam komunikasi yang tentu ada termasuk kesulitan memahami pesan dan perbedaan dalam merespon maka diperlukan pendekatan dan perlakuan yang berbeda.
The Representation of Javanese People in the Film "De Oost" by Jim Taihuttu: A Semiotic Analysis by Roland Barthes
Authors: Arya Aurel Evan , Sokowati Muria Endah
Published: December 2024

Jim Taihuttu's film "De Oost" explores the Dutch colonial period in Indonesia and has drawn attention from researchers interested in how Javanese people are portrayed in cinema. The study employs Roland Barthes' semiotic analysis to analyze the film's representations, revealing that Javanese characters are frequently depicted in stereotypical and subordinate roles that are influenced by Western perspectives. This analysis examines both the apparent and deeper meanings of the representations. Although certain sequences endeavor to demonstrate the complexity and agency of Javanese characters, these representations continue to primarily perpetuate preexisting stereotypes, underscoring the necessity of more precise and equitable media representations. In the film "De Oost," Javanese characters are predominantly depicted in a manner that aligns with the Orientalist perspective, which implies that they are frequently portrayed as stereotypical and of lesser significance. The majority of Javanese characters are depicted in stories that are dominated by Western perspectives, despite the fact that certain sequences attempt to demonstrate their depth and strength. This means that even though there are moments of resistance, the overall portrayal doesn't significantly challenge the dominant narrative.
Prevalence and factors associated with exercise in pregnant women in Dessie town health facilities, Ethiopia
Authors: Yimer Abdusellam , Endris Seada , Wossen Alemtsehay , Abate Mengistu
Published: December 2024

Background: Physical exercise (PEx) consists of planned, repetitive and intentional movements that can reduce the risk of pregnancy related complications. Worldwide, there is a high rate of physical inactivity during pregnancy. Therefore, this study aimed to assess prevalence and factors associated with practice of PEx during pregnancy among antenatal care attendants at selected health facilities in Dessie town, Ethiopia, 2023.
Methods: An institutional based cross-sectional study was conducted among 642 pregnant women receiving antenatal care service from 20th May to 20th July, 2023. The study participants were selected by using systematic random sampling technique.  Data were collected through pretested, face to face interviewer-administered. The data were cleaned, coded and entered into EPIDATA version 4.6 and analyzed by SPSS version 25. Binary logistic regression analysis was performed to identify factors associated with practice of PEx during pregnancy. Finally, the AOR at 95% confidence interval with p<0.05 in multivariable analysis were considered to declare a variable is statistically significant.
Results: The prevalence of practice of PEx during pregnancy in this study was 32.2%. Age of women (25 to 34 years), antenatal care follow-up (three and more times), hadn’t history of abortion, ever done PEx before becoming pregnant, and good knowledge towards PEx during pregnancy were found positively statistically significant association with practice of PEx during pregnancy. 
Conclusions: In the current study, nearly one-third of the study participants practiced PEx during current pregnancy. Therefore, antenatal care providers should give advice pregnant women to strengthen antenatal care follow-up and offer health education and counseling regarding PEx during pregnancy during antenatal care follow-up.
Efficacy for epidural fenatnyl in single level fenestration lumbar discetomies: An randomised controlled trial
Authors: Shankar TC Ravi
Published: December 2024

: Lumbar disc prolapse is among the most frequent causes of Back pain resulting in surgery accounting for 5% of all lumbar surgeries. In this study, post operative effecgtiveness of fentanyl in lumbar disc prolapse patients is being assessed. Pateints who undergo fenestration discectomies have moderate to severe pain at surgical site, which lasts for 48 to 72 hours post surgery.

: This study would evaluate the efficacy of intra-operative epidural fentanyl infiltration on post surgical analgesia following single-level fenestration discectomy and the adverse events that occurred among the groups.

60 patients were into two groups (Group A: Control & Group B: Drug). Between November 2018 and February 2021, 30 patients in the drug group—injected with intraoperative epidural fentanyl (1 mcg/kg weight) and 30 patients in the control group with placebo. All patients were followed up for the next 3 days. VAS scoring was used to assess post-operative pain and data on time to mobilization, the requirement for rescue analgesia (50 mg IV tramadol).

Group A and Group B's post-operative VAS scores at the first post-operative hour were statistically significant (value of p = 0.02). The respective times for mobilization were 19.6 and 18.4 hours.

A single-level discectomy patient's (p=0.02) early postoperative pain (VAS) was statistically significantly reduced after intraoperative fentanyl infiltration and there were no appreciable side effects. Although not statistically significant(p>0.05), there was a earlier time to mobilization in the test group.
A case of infected old non-united left shaft femur fracture treated with debridement + sequestrectomy + ilizarov fixation with stimulant insertion
Authors: Chaturvedi Dev , Banker Parth , Kubhavat Hasmukh L , Shah Darshit Kamleshkumar , Parmar Avdhesh
Published: December 2024

To assess treatment outcome of ilizarov technique in infected non-union of femur fracture. This is a case of shaft femur fracture operated with femur interlocking nail which got infected. Patient undervent removal of implant with debridement followed by sequestrectomy followed by ilizarov fixation for infected nonunion and stimulan insertion. Infection got cured along with complete union of fracture site and patient is now walking with full weight bearing. Ilizarov technique is a good salvage operation for infected non-union of femur. Limb salvage is always preferred over prosthesis if limb is viable, without neurovascular deficit also if the patient is committed financially and mentally with patience to save the limb.
Jardim vertical tipo cortina verde: efeito no sombreamento de edificações para o clima subtropical do sul do Brasil
Authors: Scherer Minéia Johann
Published: December 2024

O jardim vertical tipo cortina verde, caracteriza-se como uma opção para o controle solar de edificações, com uso de vegetação trepadeira que se desenvolve em frente e afastada das fachadas. A capacidade de proporcionar sombra pode repercutir no desempenho termo energético do edifício, considerando as características da vegetação e do clima. O objetivo deste artigo é avaliar um método para quantificação da variação anual na capacidade de sombreamento de espécies trepadeiras, determinando o Percentual de Transmissão Solar (PTS) de sua folhagem e utilizando estes dados em simulações computacionais que anteveem o consumo de energia para climatização e iluminação, em um edifício modelo, no contexto do clima subtropical do Sul do Brasil. A metodologia de pesquisa dividiu-se em duas fases, sendo a primeira experimental e a segunda envolvendo simulações computacionais. Sobre o método de avaliação adotado, os resultados demonstraram sua viabilidade e aplicabilidade, passível de ser reproduzido para caracterizar outras espécies de vegetação trepadeira. Já sobre os resultados das simulações, constatou-se que a performance na redução do consumo de energia da edificação foi favorável quando o sistema de sombreamento adotado foi a vegetação. Ainda, é perceptível a influência na variação do PTS da espécie avaliada nos diferentes meses do ano, adaptando-se às características do clima estudado.
Acceleration of cements with phosphogypsum through sodium chloride: analysis of compressive strength and corrosive potential
Authors: Medeiros Matheus Henrique Gomes de , Alves Caroline Vieira , Costa Rayara Pinto , Kirchheim Ana Paula , Suzuki Seiiti
Published: December 2024

Phosphogypsum, a byproduct of phosphoric acid production in the fertilizer industry, is an environmentally friendly source of calcium sulfate for controlling the setting time in cements, replacing gypsum. However, as it is a waste product, it can contain impurities such as F- and P2O5, which may prolong the setting time beyond the desired duration and reduce initial mechanical strength. A solution to this problem is the use of hydration/strength accelerators, of which several types are available. Considering cost, sodium chloride can be an attractive option. However, it is known that chlorides can cause corrosion in reinforcements. Therefore, the incorporation of these materials as setting accelerators in concrete requires caution regarding the durability of structures. This study aims to analyze the influence of using phosphogypsum in Portland cements and the impact of sodium chloride as an accelerator. Tests were conducted to verify the behavior of the mixtures at early ages, using isothermal calorimetry in pastes, compressive strength, and corrosion potential in concretes. The results confirm that the presence of phosphogypsum delays the setting process but does not significantly affect the final strengths. Additionally, the tested chloride levels did not indicate a high probability of reinforcement corrosion.
CALÇADÃO DE BAURU, SP: CAMINHAR E CARTOGRAFAR
Authors: Barros Vitor Giulianetti , Fiorin Evandro , Hirao Helio
Published: December 2024

Todo espaço é definido por meio de suas relações, por marcações de relações sociais no espaço-tempo em que se encontram, percebidas por quem habita o ambiente. Tais relações se encontram em processos de territorialização, tendo o ritmo como um de seus definidores, por meio de uma organização de intensidades no tempo, em encontros e relações, que só podem ser percebidas e imaginadas por meio de uma experiência existencial do espaço. Assim busca-se propor uma pesquisa cartográfica que revele e reconheça as relações cotidianas no calçadão Batista de Carvalho na cidade de Bauru no estado de São Paulo. Nesse contexto, o propósito deste trabalho reside na compreensão das relações do calçadão, mediada a prática do caminhar e da pesquisa cartográfica como processos metodológicos. O artigo começa com uma discussão teórica sobre o conceito de territorialidades e a relação do caminhar como recurso de pesquisa para se habitar o espaço, é buscado apreender os ritmos, relações e limites do ambiente pesquisado. A seguir é feito um levantamento histórico do local a ser pesquisado, contando parte de sua história e apresentando sua evolução ao longo do tempo. Por fim, procura apresentar os territórios que se mostraram presentes durante os diferentes dias de visita ao local como forma de registro, de um espaço que está prestes a ser revitalizado pela prefeitura da cidade. De forma conclusiva, anseia-se, através deste estudo, não apenas apreender e apresentar as relações e espacialidades do local, mas também desenvolver métodos e estratégias para representar visualmente os registros, de modo a permitir a partilha da experiência adquirida. Que por sua vez, pode ser uma valiosa ferramenta para compreensão, valorização e preservação dos espaços urbanos.
NECESSIDADE E DÉFICIT HABITACIONAL: UMA ANÁLISE DAS HABITAÇÕES PRECÁRIAS NO MUNICÍPIO DE JACAREÍ-SP
Authors: Forcel Priscila Kauana Barelli , Olivatto Tatiane Ferreira , Inguaggiato Felipe Facci , Miyasaka Elza Luli , Da Cunha Tiago Augusto
Published: December 2024

A industrialização e urbanização na América Latina principalmente na década de 1960, resultaram em problemas estruturais como ocupações irregulares e especulação imobiliária. Com um déficit habitacional superior a 6 milhões de unidades em 2024, a Fundação João Pinheiro contabiliza déficits quantitativos e qualitativos e destaca a urgência de políticas públicas eficazes. Este estudo objetiva analisar o déficit habitacional de Jacareí-SP, com foco em habitações precárias. Metodologicamente, revisou-se legislação municipal e documentos locais, além de analisar dados censitários, em 2010, Jacareí apresentou 287 habitações precárias. Os resultados indicam a necessidade de intervenções detalhadas para políticas públicas mais eficazes. Considera-se que o município reconhece suas habitações precárias e formula iniciativas para sua supressão. No entanto, o processo é contínuo, pois novas habitações precárias surgem ao longo dos anos em diferentes locais.
On the non-actuality inferences in Turkish avertives
Authors: Dikmen Furkan , Demirok Ömer
Published: December 2024

Languages have various forms of expressing implications of imminency and non-actuality. While a variety of constructions such as imperfectives, proximatives or adverbs like almost crosslinguistically imply the counterfactuality of the event in question, some languages like French and Turkish have exclusive morphemes expressing imminence while at the same time logically asserting the non-actuality of an event. This study has a particular focus on the Turkish morpheme -(y)Ayaz, which when combined with a predicate indicates that the event expressed by the predicate has not been actualized although it was close to be so. We argue that this is part of what -(y)Ayaz asserts, and provide a compositional semantics for sentences involving this morpheme. Finally, we show that our semantics sheds light on the combinatorial restrictions concerning lexical aspect and outer aspect.
BRICS ÜLKELERİNDE ENDÜSTRİ 4.0 DÖNEMİNİN EKONOMİK BÜYÜMEYE YANSIMALARI
Authors: Aba Şenbayram Emel
Published: December 2024

Endüstrileşme, üretim sürecine teknolojik gelişmelerin entegre edilerek verimlilik artışını hedeflerken aynı zamanda ülkelerin kalkınmasındaki en önemli göstergedir. Dördüncü evresini yaşamakta olan endüstrileşmenin son yıllarda dijitalleşmenin de etkisi ile önemi daha da artmaktadır. Endüstri 4.0 gelişmiş ekonomilere sahip ülkelerin rekabet avantajı sağlamak ve küresel ekonomide güç elde etme noktasında avantaj sağlayacaktır. Bu noktadan hareketle bu çalışma ile Endüstri 4.0’ın, milli gelirlerindeki hızlı artışla dikkat çeken BRICS ülkelerinin (Brezilya, Rusya, Hindistan, Çin ve Güney Afrika) ekonomik büyümeleri üzerindeki etkisinin tespiti amaçlanmaktadır. 2004-2023 dönemine ait yıllık verilerinin kullanıldığı araştırmada, panel veri analiz yönteminden yararlanılmıştır. Elde edilen bulgular neticesinde, Endüstri 4.0’ın BRICS ülkelerinin ekonomik büyümeleri üzerinde pozitif etkiye sahip olduğu tespit edilmiştir.
THE FINANCIAL BENCHMARKING OF GLOBAL RAILWAY COMPANIES
Authors: Özcan İsmail Çağrı
Published: December 2024

The railway industry, traditionally under public ownership and management, has witnessed an increasing emphasis on performance measurement due to the commercialization, corporatization, and privatization trends over the past four decades. Most relevant studies in the performance measurement of rail companies adopt non-parametric methods like data envelopment analysis (DEA), which largely rely on operational and physical characteristics. Using an international sample of 39 railway companies from 12 countries from 4 continents, this study clusters publicly traded railway companies with respect to their financial characteristics such as capital structure management, profitability, cost efficiency, and investment management with the aim of a financial benchmarking. The findings highlight the effectiveness of cluster analysis in comparing the financial performances of rail companies and demonstrate its applicability to other sectors.
The activities of local gendarme bodiesto ensure state and public security inthe Privislinsky Territory of the Russian Empire (1870–1890s)
Authors:   Main Research Center of the Federal Service of theNationalGuard Troops of the Russian Federation, Ananyev Sergey V.
Published: December 2024

The article examines the activities of local gendarme bodies of the Privislinsky Territory of the Russian Empire in the 1870–1890s. Listed
are some police and political measures subsequently adopted by the executive authorities in ensuring state and public security on the western
outskirts of the empire. It is noted that the activities of the local gendarmerie became an integral part of the measures of the tsarist government
to ensure state and public security,carried out inconjunction with other law enforcement structures of the empire. Examples of the participation
of the gendarme corps in the fight against Polish revolutionaries and socialists, the dedication of its personnel are given. This study deepens the
general information available in domestic historiography on this issue. Based on the work carried out, it was concluded that the gendarmerie of
the region played an important role, both in the suppression and in the fight against the revolutionary movement in the region.