bluuebunny/crossref_metadata_2025 huggingface dataset:
Validity of the Gait Deviation Index in children and adolescents with juvenile idiopathic arthritis
Authors: Bazarnik-Mucha Katarzyna , Guzik Agnieszka , Szczepanik Magdalena , Snela Sławomir , Drużbicki Mariusz
Published: November 2022

Purpose: Effectiveness of the Gait Deviation Index (GDI) in patients with juvenile idiopathic arthritis (JIA) is unknown. The aim of this study was to investigate the validity of the GDI as an outcome measure of gait disturbance children with JIA. Methods: Fifty children and adolescents with JIA were included into the study. The control group included 50 healthy children without gait disorders, matched for age and gender. The kinematic gait parameters were measured using a 3D movement analysis system. Walking speed, walking distance, cadence, step length and single support time were also evaluated. Results: The findings show a statistically significant difference between the values of GDI for the right leg in the study group and the controls (p = 0.036). The individuals included in the study group achieved significantly lower values in this parameter (mean 94.92 ± 8.38 vs. mean 100.00 ± 10.00). The GDI value for right and left leg and the mean GDI value showed low (0.3 ≤ |R| < 0.5, p < 0.005) to moderate (0.5 ≤ |R| < 0.7, p < 0.001) correlations with the other gait parameters and measures. Conclusions: The GDI scores were lower in individuals with JIA compared to controls. This difference in the GDI values was only significant for the right leg. The GDI values showed low to moderate correlations with other gait parameters.
Mechanical properties of the mouse femur after treatment with diclofenac and running exercises
Authors: Trzaskowska Aleksandra , Mielcarek Sławomir , Lehmann Tomasz , Pruszyńska-Oszmałek Ewa , Kołodziejski Paweł , Głowacki Maciej
Published: November 2022

Purpose: The flexible properties of the bone are essential for the movement and protection of vital organs. The ability of a bone to resist fractures under the influence of large muscles and physical activity depends on its established mechanical properties. This article discusses how exercise such as treadmill running and taking non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, affect the musculoskeletal system by modifying the elastic and thermal properties of the left femur of a mouse. Methods: The research was conducted using 9-week-old C57BL/6J female mice. In order to investigate the elastic and thermal properties of bones, dynamic mechanical analysis (DMA) and differential scanning calorimetry (DSC) were performed. Results: The study of elastic properties, followed by in-depth statistical analysis, shows that taking diclofenac slightly reduces the elastic parameters of the bones under study. These changes are more pronounced in DSC studies, the shift of the observed endothermic peaks is on the order of several degrees with a simultaneous increase in the enthalpy of this process. Conclusions: The opposite effect of the applied factors – diclofenac and running – on the elastic properties of the bones of the examined mice was found. The external factors – running and diclofenac – modify the basic parameters of the endothermic process associated with the release of water.
Kinematic analysis of L4–L5 spinal segment with spondylolysis and different types of grade 1 spondylolisthesis: a nonlinear finite element study
Authors: Yaroub Suhaib , Hamandi Sadiq J. , Mohson Khaleel
Published: November 2022

Purpose: This work aimed to evaluate and characterize the motion of the fourth and fifth lumbar vertebrae functional spinal unit with spondylolysis and different types of grade 1 spondylolisthesis using the finite element method. Methods: Nine nonlinear three-dimensional finite element models were reconstructed from computed tomography scans to five educational fourth and fifth lumbar vertebrae models. The intervertebral disc was simulated in two conditions: four models with healthy discs and five models with degenerated discs. Each model consisted of two vertebrae divided into three bony parts, two endplates, an intervertebral disc and five ligaments. The flexion, extension, lateral bending and rotation loading conditions were simulated, and the ranges of motion were measured and plotted. Results: In flexion, compared to the baseline intact model, the most significant increase in the range of motion was experienced by the isthmic spondylolisthesis model, while in extension, a reduction in the range of motion was measured in both prolonged pars and unilateral pars defect and healthy disc models. In degenerated disc results, the unilateral pars defect and degenerative spondylolisthesis models had the lowest range of motion. No large differences were noticed in lateral bending results. Lastly, in axial rotation, the most significant increase in the range of motion was measured in the isthmic spondylolisthesis model, followed by the spondylolysis model and similarly, in the degenerated disc models. Conclusions: The isthmic spondylolisthesis displayed hypermobility in flexion and rotation. Moreover, the model with unilateral pars defect showed hypermobility in axial rotation only. Finally, hypomobility in all movements was noticed with the degenerative spondylolisthesis model.
Analisis cacat pada produk kemasan (karung) kedelai dengan menggunakan metode six-sigma dan fishbone diagram pada PT. FKS Multiagro tbk Surabaya
Authors: Aldo Winata , L Parulian  , D Yusi
Published: November 2022

Kedelai merupakan salah satu kebutuhan pokok yang dibutuhkan oleh masyarakat umum. PT. FKS Multi Agro merupakan industri yang bergerak dibidang pengolah distribusi kacang kedelai. Untuk mencapai tingkat produktivitas dan keuntungan yang tinggi, suatu industri perlu melakukan sebuah monitoring dan evaluasi terkait capaian yang telah ditentukan sebelumnya. Dari hasil studi lapangan diketahui bahwa terdapat hambatan yakni kecacatan pada kemasan kedelai terdapat barang reject akibat karung yang jahitannya kurang kuat. Sehingga untuk mengatasi masalah tersebut dibutuhkan metode yang dapat mengidentifikasi permasalahan yang ada serta dapat memberikan usulan yang tepat guna meminimalisir permasalahan tersebut. Metode six sigma digunakan untuk mencari permasalahan yang terdapat pada alur produksi beserta mengurangi cacat. Sedangkan fishbone diagram digunakan untuk analisa penyimpangan pada produk cacat dan mencari penyebab terjadinya permasalahan produk cacat. Setelah dilakukan analisis diketahui nilai besaran sigma PT. FKS MULTIAGRO berada pada nilai 4-sigma yang setara dengan dunia di Negara Amerika. Namun demikian masih terdapat hal hal minor yang menjadi faktor penghambat PT. FKS MULTIAGRO untuk dapat mendekati nilai zero defects, hal tersebut terkait dengan CTQ dari produk kedelai kemasan itu sendiri yakni kemasan yang digunakan memiliki kecacatan pada karung yang mengakibatkan Produk yang dihasilkan dianggap reject serta rawmaterial harus kembali diolah ke tahapan awal
Penerapan metode overall equipment effectiveness untuk meningkatkan produktivitas mesin di PT. YE
Authors: Erwin Barita Maniur Tambunan  , Ilahy Rosihan Rifda , Fauzan Ahcmad , Nadia Ainun , Spalanzani Widya
Published: November 2022

PT. YE adalah perusahaan yang terdiri dari perusahaan-perusahaan swasta nasional yang bergerak dibidang Minyak & Gas Bumi (MIGAS), dan dibentuk untuk mencapai optimalisasi dan efisiensi pemanfaatan sektor energi di Indonesia dan luar negeri. Pada Bulan Januari – Juni 2018 terdapat 3 Mesin Austcold Gas Engine Caterpillar 3512 yang memiliki tingkat downtime yang tinggi. Tujuan dari penelitian ini adalah mengetahui nilai OEE untuk mesin Austcold 1 gas engine Caterpillar 3512, Mengetahui six bigg losses yang paling dominan pada mesin Austcold 1 gas engine Caterpillar 3512 dan mengetahui biaya yang ditimbulkan dari kerusakan mesin Austcold 1 gas engine Caterpillar 3512. nilai rata-rata OEE untuk mesin Austcold 1 gas engine Caterpillar 3512 adalah 78,30% dengan faktor six big losses terbesar adalah reduced speed loss dengan nilai 33,09%. Biaya yang ditimbulkan akibat downtime mesin Austcold 1 gas engine Caterpillar 3512 adalah sebesar Rp 2.598.240.000,00
Design and Experimental Investigation of Four-Bar Dynamic Testing Machine
Authors: Maarij Muhammad , Ali Muhammad , , Manzoor Muhammad Shehryar
Published: November 2022

This project involved fabricating and experimental investigation of a dynamic testing machine for four-bar mechanisms with various applications. The simple crank rocker inversion is selected, and the kinematic design of the four-bar mechanism is done by keeping in view the Grashof rotatability criteria and the dynamic design required factoring in the forces acting on various links. The flywheel is designed to minimize the fluctuations in the torque required to drive the mechanism. DE-ASME Elliptic criteria is used for the shaft design and selection of bearing. For transmitting power from the AC motor to the crankshaft, a V belt and a pulley are used as the belt helps dampen the vibration effects in the mechanism. The linkages were fabricated, and the mechanism was assembled. ADXL335 accelerometer sensor is mounted on the apparatus to measure the acceleration of a point on the coupler. This acceleration data was then integrated using numerical techniques to estimate velocity and displacement. The model changes can be adjusted according to the dimensions of the bars and angles between the bars to simulate the performance of the mechanism. Due to the inherent offset in the sensor, an error was included in the data. However, the results obtained using such methods were satisfactory in visualizing the behaviour of data representing the system’s motion under running conditions. The errors in the result can be minimized using more advanced integration techniques and sensitive sensors for measurement and instrumentation. This research aims to contribute vital research knowledge for developing sustainable four-bar dynamic testing mechanisms.
Biosynthesis of Nanoparticles using Microorganisms and their Applications
Authors: Patni Rajita , Soloman Prama Esther , Lal Chhagan , Jain Pankaj Kumar
Published: November 2022

Materials behave in a different way when they are in their nano sizes. Nanomaterials encompass a high surface-to-volume ratio, a high adsorption capacity, high sensitivity, and reactivity, hence these can be efficiently used for textile wastewater treatment. Numerous studies have shown that nanoparticles can effectively eliminate various pollutants of domestic and industrial effluent. Nanoparticles are conventionally synthesized by physical and chemical methods but these methods use toxic chemicals, complicated procedures, and expensive materials. Presently, enzymatic processes are the most preferred method as they are economically cheap and environmentally sustainable. Microorganisms, break down the metal salts into metal nanoparticles, which can be isolated and used for textile dye degradation. This review epitomizes the various biosynthesized metal and metal oxide nanoparticles by different microorganisms and if they are efficient to degrade diverse textile dyes.
Role of Abiotic Factors on House Dust Mite Population: Control and Allergen Avoidance - A Review Article
Authors: Dhaliwal Amandeep Kaur
Published: November 2022

House dust mites (HDM’s) are an important source of indoor allergens in the house dust and cause various kinds of allergies. They are strongly influenced by abiotic factors such as temperature, relative humidity and seasonal variations. HDM’s are present in houses all over the year but their number varies in different seasons and habitats. The moderate environmental temperature, high relative humidity and adequate food sources are the key factors for their proliferation. The season has a great effect on the mite population. In the rainy season, moderate temperature and high relative humidity are the favorable conditions for the growth of mites, and the population of mites reaches a peak level. Whereas, high temperature and low relative humidity during summer season significantly reduce the mite population level and in the winter season, fall in temperature will drastically reduce the mite number because mites perish due to chilling. Relative humidity of a particular place plays an important role in the growth of mites. By controlling the relative humidity of a particular place, the HDM allergens can be reduced in that place. The prevalence of these mites and their allergen content vary within the locations in the home. Mattresses, carpets, sofas are the main reservoir of HDM’s, as the dust and shed skin scales accumulate in these places and provide abundant nutrition to dust mites. To reduce the allergen content from houses, frequent cleaning and vacuuming of mattresses and pillows, the use of encasement should be advised for allergic subjects.
Impact of environmental stress on biochemical profile and fitness traits in Drosophila malerkotliana
Authors: Singh Shailesh , Anjali  , Singh A.K.
Published: November 2022

In natural condition, climatic changes affect the internal state of an organism. Effect of different environmental conditions on energy metabolites level can reveal the survival and fitness of organisms. In ectothermic insects, temperature plays a crucial role in influencing a number of fitness traits like duration of life cycle, survival, longevity and reproductive efficiency. Changes in temperature may lead to alteration in the levels of different biochemical profiles like body lipid, protein and glucose, as a measure to cope up with the changed environmental conditions. In the present study, mass culture stock of fruit fly, Drosophila malerkotliana, collected from Bilaspur, Chhattisgarh was examined for the effect of temperature on the body lipid (triglyceride), protein and reproductive ability, particularly, fertility and productivity in this species. The experimental results have indicated that transient thermal stress caused a significant effect on body triglyceride and protein content on age-dependent manner. Fitness traits, i.e., fertility and productivity were observed to be severely influenced by fluctuating temperature in the young as well as old age flies. Therefore, transient temperature stress leaves its distinct impact on the biochemical profile, fertility and productivity in D. malerkotliana.
Finite-time synchronization between finance hyper-chaotic systems with hyperbolic nonlinearity via adaptive control
Authors: Shuklaa Vijay K. , Kumar Abhishek , Mishra Prashant K.
Published: November 2022

This paper examines the finite-time synchronization of identical hyper-chaotic finance systems with hyperbolic nonlinearity. The adaptive control technique has been used to guarantee the synchronization between master and slave systems. The Lyapunov stability theory has been used to stabilize the proposed controller. Some numerical results are depicted through graphs, which validates the applicability and efficiency of the suggested technique.
Spectroscopy of Gossans and associated lithology and its implication in geo exploration- A Case Study in the Parts of Rajpura-Dariba Group, Rajasthan, India
Authors: Rao D Anantha , VS Joji , Guha Arindam , Kumar K Vinod , Rao E Dhananjaya
Published: November 2022

The gossan exposures are sparsely distributed in the Dariba area and for detection and mapping of gossan and its associated lithology, spectral signatures have been used. Spectral reflectance and absorption features in VNIR-SWIR (visible and near-infrared - shortwave infrared) domain provide the scope for delineating the mineralogy of rocks. In the study, a few spectral mapping methods like Spectral angle mapper, Spectral information divergence and Band ratio indices were applied to ASTER (Advanced Space borne Thermal Emission Reflection Radiometer) calibrated data for delineating the lithology. These mapping methods could delineate boundaries for gossan and its associated rocks of Dariba; but above out of all mapping methods, spectral angle mapper spatial map has been validated with base detailed geological map in quantitatively and accuracy much better than spectral information divergence indices. The band ratio can demarcate the boundaries for gossans in the 4/2 ratio map, in the same way for associated rocks of Carbonates were well delineated in the (7+9)/8 ratio map and Quartzite 4/6 ratio map. Finally, the overextended boundaries of Dariba gossans and associated units found in the above validated spatial map, can be confirmed with field evidence can be helpful to update the base map of Dariba
Secretory acetylcholinesterase activities in fresh Ascaridia galli adult (Nematoda), excretory/secretory products, post-secretory parasite and gastrointestinal tissue of host Gallus gallus domesticus: A preliminary comparative study in host-parasite relationship
Authors: Maity Sulagna , Mondal Subhoshree , Ghosh Arup Kumar , Chakrabarti Ipsit
Published: November 2022

Acetylcholinesterase (AChE), an esterase enzyme, terminates synaptic transmission by hydrolyzing the neurotransmitter acetylcholine into acetate and choline. Found in membrane-bound form, AChE has also been reported to be secreted in soluble form by numerous enteric helminth parasites. Secretory AChE is considered to be an immunomodulator that may promote the survival of parasites against the host’s immune response. Our aim was to investigate the immunomodulation and survival strategy of helminth parasites Ascaridia galli inside the host Gallus gallus domesticus through analysis of AChE activity. The parasites, host intestinal tissue and post-secretory parasites were subjected to centrifugation, followed by AChE activity determination. The AChE activities among intestinal tissue, fresh parasites, excretory/secretory (E/S) product and post-secretory parasites were even compared. An inverse relationship between the reduced enzyme activity of the host’s intestinal tissue and the increased enzyme activity in the parasite was observed. Our study indicates that the increased AChE activities in fresh parasites, postsecretory parasites and E/S product are their survival strategy as well as a part of their adaptive features vis-à-vis the hostile environment of the host’sintestine.
A Rician Noise Prediction and Removal Model for MRI Head Scans using wavelet based Non-Local Median Filter
Authors: Kalaiselvi T. , Anitha T. , Sriramakrishnan
Published: November 2022

In the medical imaging field, anatomical structure preservation is a difficult task during the denoising process. Magnetic resonance imaging (MRI) scanner corrupts the images by the Rician noise during the acquisition process. Rician noise affects the diagnosis and treatment planning for the subjects. Regenerating noise-free images is a time-consuming process with limited MR scanner resources available in developing countries. Therefore, the medical industry utilizes the advancement of computer-aided automatic denoising methods. This article presents a novel denoising method for Rician noise using a wavelet-based non-local median filtering (WNLMed) technique. The work contains three phases: noise estimation, wavelet thresholding using a lifting scheme, and non-local median filter (NLMed). Materials used for this experiment are collected from the Brainweb repositories and tested with validation metrics such as normalized absolute error (NAE), peak signal to noise ratio (PSNR), structure similarity index measure (SSIM), the figure of merit (FOM), and compared with the state-of-the-art methods. The method yields high PSNR value than other methods.
A statistical analysis of X- class solar flares and their association with the super active regions during solar cycles 23- 24
Authors: Singh Abha , Chaudhary Anurag , Rathore V. S. , Singh A. K.
Published: November 2022

The A statistical distribution function of X-class flares and their association with super-active regions (SARs) during two recent solar cycles 23-24 have been analyzed. The obtained results show that, during solar cycle 23, 57.60 % of the total number of Xclass flares coincides with a set of X1.0 - X1.9 flares, 15.20 % to X2.0 - X2.9, 12.80 % to X3.0 - X4.9, 9.60 % to X5.0 - X9.9, and 4.80 % to ≥ X10 flares. During solar cycle 24, 61.20 % of the total number of X-class flares coincides with a set of X1.0 - X1.9 flares, 22.40 % to X2.0 - X2.9, 8.16 % to both the X3.0 - X4.9 flares, and X5.0 - X9.9 flares. None of the ≥ X10 flares. All X-class flares are found to be in a scattered manner in solar cycles 23 and 24. Among the cycles, solar cycle 24 has been observed relatively very weak cycle and the total number of X-class flares diminished in comparison to previous solar cycles. During solar cycle 23, 29.16% of the X1.0 - X1.9 flares, 36.84 % of the X2.0 - X2.9 flares, 43.75 % of the X3.0 - X4.9 flares, 83.33 % of both the X5.0 - X9.9 flares, and 100.00 % of the ≥ X10 flares were produced by SARs. While during solar cycle 24, 20.00 % of the X1.0 - X1.9 flares, 36.36 % of the X2.0 - X2.9 flares, 25.00 % of the X3.0 - X4.9 flares, 75.00 % of the X5.0 - X9.9 flares, and 0.00 % of the ≥ X10 flares were produced by SARs.
Control chart using bootstrap method for logistic-exponential percentiles
Authors: Saha Mahendra , Yadav Abhimanyu Singh , Rao G. Srinivasa , Dey Sanku , Sarkar Bipul
Published: November 2022

Lan and Leemis (2008) introduced logistic-exponential (LE) distribution which has varied applications in lifetime modellings. In this article, we consider parametric bootstrap control charts (BCCs) for detecting a shift in the percentile of LE distribution in a process monitoring situation. Four parametric BCCs based on maximum likelihood method, method of least squares, method of Cramer-von-Mises and ` method of maximum product of spacings are used for monitoring percentiles of LE distribution. We perform simulations to see the performances of the proposed four BCCs with respect to average run length. Finally, one data set is analyzed to illustrate our results.
Narrativa del artivismo como tendencia en la publicidad
Authors: Sánchez Serrano Diana , Ortega Fernández Eglée , Toledano Cuervas-Mons Fernando
Published: November 2022

La democratización de las comunicaciones a través de los medios sociales ha potenciado un cambio en el perfil del consumidor. Se percibe que la sociedad muestra una conciencia más abierta, centrada en la sostenibilidad, el cuidado del ambiente y la inclusión social. El artivismo, entendido como un fenómeno que saca el arte de los museos y galerías para darle una función social, podría ser una oportunidad para un cambio de modelo donde las emociones que despierta el arte y el activismo se unan para lograr una narrativa con un mayor efecto en la audiencia a quien busca llegar la publicidad.
Aplicación de herramientas de neuromarketing a la investigación de mercados
Authors: Blázquez-Resino Juan José , García Bravo Miguel Ángel
Published: November 2022

El neuromarketing ha conformado un área emergente capaz de establecer vínculos entre el estudio del comportamiento del consumidor y la neurociencia, basándose en innovaciones tecnológicas y tecnologías de neuroimagen capaces de obtener datos del cerebro. La aplicación de las tecnologías de neuroimagen en la investigación de mercados ha supuesto un nuevo universo de actuación en términos de recogida de información, en base a ello, el presente estudio tiene como objetivo realizar un análisis de las diferentes herramientas de neuroimagen, basándose en una metodología de análisis de elementos teóricos combinada con estudio de casos concretos.
Publishers y publicidad digital: pluralidad de formatos
Authors: López Castro Raquel , Valderrama Santomé Mónica
Published: November 2022

La prensa como medio publicitario se ha transformado ante los problemas adaptativos al lenguaje digital. En este texto se exploran los modos de abordaje a esos cambios en nueve publishers: desde nativos digitales, a cabeceras nacionales y de cobertura autonómica. Se trata de elaborar una propuesta completa y armonizada, a través de un trabajo de observación directa de los formatos de publicidad con una comparativa entre las denominaciones estándares y las utilizadas en las tarifas del sector. La investigación arroja luz sobre cuánto se ha heredado de los medios impresos o la necesidad de revisión de la nomenclatura.
Analisis Perhitungan Harga Pokok Produksi dengan menggunakan Metode Process Costing pada Pabrik Tahu dan Tempe Sumber Sari Kota Gorontalo
Authors: Hamidah Amalia , Monoarfa Rio , Taruh Victorson
Published: November 2022

Penelitian ini bertujuan untuk menganalisis Perhitungan Harga Pokok Produksi dengan Menggunakan Metode Process Costing dalam menentukan harga jual pada Pabrik Tahu dan Tempe Sumber Sari Kota Gorontalo. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan deskriptif. Sumber data utama yang digunakan adalah data primer yang diperoleh dari wawancara dan dokumentasi pada pabrik. Teknik analisis data dalam penelitian ini adalah analisis deskriptif. Hasil penelitian ini menunjukkan bahwa perhitungan harga pokok produksi dengan perhitungan pabrik, harga pokok produksinya lebih kecil atau kurang tepat karena pabrik Tahu dan Tempe Sumber Sari Kota Gorontalo tidak memasukkan biaya produksi secara rinci kedalam biaya produksinya. Sedangkan pada perhitungan harga pokok produksi menggunakan metode process costing dapat menghasilkan harga pokok produksi yang tepat karena metode process costing merinci semua biaya secara jelas, baik itu biaya bahan baku, biaya tenaga kerja langsung, dan biaya overhead pabrik.
Analisis Faktor-Faktor yang Mempengaruhi Kualitas Laporan Keuangan di Kabupaten Boalemo (Studi pada Organisasi Perangkat Daerah Kabupaten Boalemo)
Authors: Bano Adawiyah R. M. , Blongkod Harun , Tuli Hartati
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh Kompetensi Sumber Daya Manusia, Sistem Pengendalian Intern Pemerintahan, Pemanfaatan Teknologi Informasi, dan Sistem Akuntansi Keuangan Daerah terhadap Kualitas Laporan Keuangan pada Organisasi Perangkat Daerah (OPD) di Kabupaten Boalemo. Penelitian ini menggunakan metode kuantitatif. Penelitian ini menggunakan data primer dengan populasi sebanyak 26 OPD dan jumlah sampel dalam penelitian ini sebanyak 4 pegawai disetiap OPD dengan total 104 pegawai. Penelitian ini menggunakan instrumen penelitian berupa kuesioner. Teknik analisis data dalam penelitian ini adalah menggunakan analisis regresi berganda. Hasil penelitian menunjukan bahwa, 1) Kompetensi Sumber Daya Manusia tidak berpengaruh signifikan terhadap Kualitas Laporan Keuangan. 2) Sistem Pengendalian Intern Pemerintahan berpengaruh signifikan terhadap Kualitas Laporan Keuangan. 3) Pemanfaatan Teknologi Informasi berpengaruh signifikan terhadap Kualitas Laporan Keuangan. 4) Sistem Akuntansi Keuangan Daerah tidak berpengaruh signifikan terhadap Kualitas Laporan Keuangan.
Failing to attend versus failing to stop: Single-trial decomposition of action-stopping in the stop signal task
Authors: Hannah Ricci , Muralidharan Vignesh , Aron Adam R
Published: November 2022

The capacity to stop impending or ongoing actions contributes to executive control over behavior. Action-stopping, however, is difficult to directly quantify. It is therefore assayed via computational modeling of behavior in the stop signal task to estimate the latency of stopping (stop signal reaction time, SSRT) and, more recently, the reliability of stopping in terms of the distribution of SSRTs (standard deviation, SD-SSRT) and the frequency with which one outright fails to react to a stop signal (trigger failures, TF). Critically, the validity of computational estimates remains unknown because we currently have no direct readouts of behavior against which to compare them. Here, we developed a method for providing single-trial behavioral readouts of SSRT and trigger failures. The method relies on an adaptation of the stop signal task in which participants respond by moving a computer mouse. In two online experiments, we used movement kinematics to quantify stopping performance (SSRT, SD-SSRT, and TF), and then applied the standard Race Model and recent BEESTS model in order to examine the convergent validity of the methods. Overall, we demonstrate good correspondence between kinematics- and model-based estimates of stopping performance at the group and individual level. We conclude that the new method provides valid estimates of stopping performance that, unlike model-based estimates, can be read out at the level of single trials. Our approach might therefore be useful for interrogating single-trial neurophysiological correlates of stopping and for large-scale, online studies of behavioral stopping.
A review on collagen as a food supplement
Authors: Musayeva Fargana , Özcan Saniye , Kaynak Mustafa Sinan
Published: November 2022

One of the most abundant proteins formed in the human body is collagen. It is responsible for the strength of body tissues in all cellular systems by establishing support networks. Collagen fibers are generally opaque and white, due to this reason they are easily recognized in the tissues. Collagen fibers, which are viscoelastic, have low extensibility and high tensile strength. The isoelectric point is around pH 5.8. Collagen is widely used as it helps blood coagulate, remodeling tissue. Although there are no known side effects, there is some concern about its role in inflammation, group-to-group variability, and possible disease transfection, given that animal-derived (natural) collagen is used in many clinical applications. Not every protein is of equal value, so not every collagen is of equal value. Thanks to its low molecular weight, hydrolyzed collagen is quickly digested by our body and enters our blood circulation. According to study, the most suitable type of collagen is the one in powder or liquid form for collagen peptides that can be easily absorbed and used by our body. It is necessary to rely on the most appropriate analysis technique to evaluate the quality feature. Techniques such as SEC, MS, HPLC and NMR are used to characterize complex peptide mixtures. Classical fibril-forming collagen includes collagen types I, II, III, V, and XI. These collagenes are characterized by their ability to aggregate into highly oriented supramolecular aggregates, forming fibrillar arrays with diameters between 25 and 400 nm. Being a natural protein and its technical characteristics, it is expected that development and consumption of collagen hydrolyzate will increase in the coming years. In this review, physical and chemical properties of collagen, types, pharmacology properties, quantity determination methods are briefly described.
Evaluation the plausibility of repurpose of levamisole and niclosamide in treatment of covid-19
Authors: Abed Ahmed Bedri , Korcan Safiye Elif
Published: November 2022

Since the world health organization declared the pandemic of covid 19, many drugs have been tested and re-evaluated to find effective treatment for the novel corona virus infection. Niclosamide and Levamisole which are FDA approved anthelmintic drugs have been evaluated by many researchers and agencies to repurpose of these drugs as additional options for existing treatment strategy used for patients with Covid-19. Hence we are trying in this review to introduce most reports that evaluated the use of Niclosamide and Levamisole for treatment of patients infected with Covid 19. We concluded that the encouraging studies regarding the repurpose of the two drugs may highlighting for further studies that can widening the options for existing treatment strategy used for patients with COVID-19.
The Biomedical Use of Radioisotopes of Thallium: A Potential Gateway to the Diagnosis of Chronic Diseases
Authors: Gupta Rajeev , Singh DP
Published: November 2022

Nuclear medicine is a specialized area of radiology that uses very small amounts of radioactive materials, or radiopharmaceuticals inside the body to examine organ function and structure for diagnosis or to target and destroy damaged or diseased organs or tissue (for treatment). Several different types of radionuclides are available. These include forms of the element technetium, thallium, gallium, iodine, and xenon. Out of these radionuclides, thallium's radioisotope plays a crucial role in the diagnosis of chronic ailments like CAD, myocardial infarction, ischemia, to name few. These diseases cause specific muscles or arteries to die or get blocked. Out of the radioisotopes of thallium, Tl-201mis is considered best suited for diagnosis of such diseases by tomography techniques such as Single Photon Emission Computed Tomography (SPECT). In this article, we have presented an overview of how thallium can be used as a nuclear medicine to test the stress level in human, mechanism of action as a tracer and perfusion imaging test by using SPECT.
PENGARUH MANAJEMEN MODAL KERJA TERHADAP RETURN ON ASSETS PERUSAHAAN MANUFAKTUR DI MASA PANDEMI COVID-19
Authors: Nurastuti Preatmi
Published: November 2022

Modal kerja adalah dana atau modal yang digunakan untuk kegiatan operasional. Untuk menentukankebutuhan modal kerja yang akan digunakan dalam kegiatan operasional dapat dilihat dari perputaranmasing-masing modal kerja itu sendiri, seperti perputaran kas, perputaran piutang dan perputaranpersediaan. Sedangkan Return On Assets (ROA) salah satu dari rasio profitabilitas yang dapat mengukurseberapa besar laba yang diperoleh perusahaan dari setiap dana yang tertanam dalam total aset. Tujuanpenelitian untuk mengetahui pengaruh manajemen modal kerja terhadap return on assets pada perusahaanmanufaktur di masa pandemi covid-19. Populasi dalam penelitian ini adalah 53 perusahaan manufaktur sektorindustri barang konsumsi yang terdaftar di Bursa Efek Indonesia (BEI) periode 2019-2021. Teknik pemilihansampel menggunakan metode purposive sampling dan diperoleh 34 perusahaan yang digunakan sebagaisampel. Metode yang digunakan adalah analisis regresi linear berganda, uji t, uji F dan uji koefisiendeterminasi (R2) dengan menggunakan SPPS versi 25. Hasil penelitian ini menunjukkan perputaran kas danperputaran piutang tidak memiliki pengaruh terhadap Return On Assets (ROA) sedangkan perputaranpersediaan memiliki pengaruh terhadap Return On Assets (ROA). Secara simultan perputaran kas, perputaranpiutang dan perputaran persediaan berpengaruh terhadap Return On Assets (ROA). Hasil uji R2 sebesar19,5%, yang artinya variabel independen (perputaran kas, perputaran piutang dan perputaran persediaan)memberikan pengaruh terhadap Return On Assets (ROA) sebesar 19,5%, sedangkan sisanya sebesar 80,5%dipengaruhi oleh variabel lain diluar model penelitian.
Pengaruh Work Life Balance, Lingkungan Kerja Dan Kompensasi Terhadap Loyalitas Karyawan Pada Rumah Sakit Khusus Daerah (RSKD) Duren Sawit
Authors: Marhalinda Marhalinda , Supiandini Anisa
Published: November 2022

Penelitian ini bertujuan untuk meneliti Pengaruh Work Life Balance, Lingkungan Kerja, danKompensasi terhadap Loyalitas Karyawan Pada Rumah Sakit Khusus Daerah (RSKD) Duren Sawit.Metodologi yang digunakan adalah metode kuantitatif deskriptif. Populasi adalah karyawan di RumahSakit Khusus Daerah (RSKD) Duren Sawit berjumlah 528 karyawan. Penentuan sampel denganteknik Random SampIing yang berjumlah 85 orang. Untuk analisis statistic ini penulis menggunakanprogram SPSS Versi 25. Hasil penelitian menunjukkan bahwa secara parsial Work Life Balanceberpengaruh positif dan signifikan terhadap Loyalitas Karyawan, Lingkungan Kerja berpengaruhpositif dan signifikan terhadap Loyalitas Karyawan, Kompensasi berpengaruh positif dan signifikanterhadap Loyalitas Karyawan. Secara simultan Work Life Balance, Lingkungan Kerja danKompensasi berpengaruh positif dan signifikan terhadap Loyalitas Karyawan. Nilai Adjusted RSquare diketahui sebesar 0,566. Saran kepada peneliti lebih lanjut yaitu mengambil sampel lebihbanyak dan menambahkan variabel lain yang dapat mempengaruhi loyalitas karyawan, sepertivariabel kepuasan kerja.
Pengaruh Motivasi Kerja, Disiplin Kerja Dan Lingkungan Kerja Terhadap Produktifitas Kerja Pada Pt Manufakturing Cikarang
Authors: Prawoto Agung , Hasyim Wachid
Published: November 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Motivasi, Disiplin danLingkungan Kerja Terhadap Produktifitas Kerja Pada PT ManufakturingCikarang, Metode penelitian yang digunakan adalah kuantitatif dengan jumlahsampel responden 94 orang karyawan pada PT Manufakturing Cikarang. Teknikpengumpulan data yang digunakan adalah kuesioner. Metode pengambilansampling menggunakan probability sampling dengan teknik simple randomsampling, Metode analisis data yang yaitu analisis regresi linier berganda denganbantuan software SPSS 22. Hasil penelitian ini menunjukan secara simultanvariable bebas motivasi kerja, disiplin kerja, dan lingkugan kerja berpengaruhsecara signifikan terhadap variable terikat yaitu produktivitas kerja karyawan,
Pengaruh Kemampuan Auditor Forensik, Pengalaman Auditor, dan Tekanan Waktu Audit Terhadap Kualitas Audit
Authors: Angelliani Angelliani , Sari Bida
Published: November 2022

Kualitas audit sangat penting sebagai proses pengambilan keputusan, makin tinggikepercayaan yang dicapai auditor maka jumlah bukti yang dikumpulkan kompeten dan relevan.Penelitian ini bertujuan untuk menganalisis pengaruh dari beberapa variabel independenterhadap kualitas audit, variabel-variabel independen yang diuji antara lain kemampuan auditorforensik, pengalaman auditor, dan tekanan waktu audit terhadap kualitas audit. Metode yangdigunakan dalam penelitian ini adalah penelitian asosiatif kausal dengan teknik kuantitatif.Jumlah sampel yang diteliti sebanyak 89 responden dari kantor Badan Pengawasan Keuangandan Pembangunan (BPKP) Pusat, data diolah dengan bantuan SPSS versi 26. Hasil penelitianmenunjukkan bahwa secara parsial kemampuan auditor forensik dan pengalaman auditorberpengaruh positif dan signifikan terhadap kualitas audit. Sedangkan, tekanan waktu audittidak berpengaruh signifikan terhadap kualitas audit. Berdasarkan Uji ANOVA terdapatpengaruh kemampuan auditor forensik, pengalaman auditor, dan tekanan waktu audit secarabersama-sama terhadap kualitas audit.
Faktor-Faktor yang Mempengaruhi Keberhasilan Usaha Pelaku UKM di Wilayah Sumur Batu Kecamatan Kemayoran
Authors: Nur Wahyuni Nur Wahyuni , Farah Diba Farah Diba , Anindhyta Budiarti Anindhyta Budiarti , Farida Farida
Published: November 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Modal Usaha, Kreativitas, danLokasi Usaha terhadap Keberhasilan Usaha pada Pelaku UKM di Wilayah Sumur BatuKecamatan Kemayoran. Metode yang digunakan adalah metode kuantitatif. Dalammetode ini pengumpulan data menggunakan teknik kuesioner dan didistribusikan kepadaseluruh pelaku UKM di wilayah Sumur Batu Kecamatan Kemayoran. Dalam analisisstatistik penulis menggunakan program SPSS 25.0 for windows. Dari pengolahan datayang dilakukan dengan program SPSS (Statistical Package for The Social Science) versi25.0 dengan populasi sebesar 270 konsumen diperoleh sampel sebesar 73 responden.Maka didapat R Square (determinasi) berganda sebesar 0.601 atau 60,1% dan sisanyasebesar 39,9% kontribusi faktor lain. Untuk nilai regresi berganda di dapat Ý= 1.288 +0.382X1 + 0.236X2 + 0.379X3 dan uji F dengan α=5% didapat nilai Fhitung sebesar 37.136dan Ftabel sebesar 3.13 berarti Fhitung> Ftabel maka H0 ditolak dan Ha diterima. Hal inimenunjukan bahwa Modal Usaha, Kreativitas dan Lokasi Usaha berpengaruh secarabersama sama terhadap Keberhasilan Usaha.
Pengaruh Pengetahuan Kewirausahaan, Karakteristik Kewirausahaan dan Kompetensi Kewirausahaan Terhadap Keberhasilan UMKM Desa Bojong Kulur
Authors: Moelrine Afhi Fadhlika , Syarif Rinaldi
Published: November 2022

Penelitian ini bertujuan untuk untuk menguji pengaruh pengetahuan kewirausahaan,karakteristik kewirausahaan, kompetensi kewirausahaan terhadap keberhasilan usaha.Penelitian ini menggunakan metode deskriptif kuantitatif. Sampel pada penelitian iniadalah 25 anggota usaha mikro, kecil dan menengah (UMKM) Desa Bojong Kulur,Kecamatan Gunung Putri, Kabupaten Bogor. Pengambilan sampel menggunakan tekniknon probability sampling. Hasil penelitian menunjukkan bahwa pengetahuankewirausahaan, karakteristik kewirausahaan, dan kompetensi kewirausahan berpengaruhpositif dan signifikan secara gabungan terhadap keberhasilan usaha, mikro, kecil danmenengah (UMKM) Desa Bojong Kulur, Kecamatan Gunung Putri, Kabupaten Bogor.Koefisien determinasi pada pengetahuan kewirausahaan, karakteristik kewirausahaan, dankompetensi kewirausahaan terhadap terhadap keberhasilan usaha memberikan kontribusisebesar 62,7% terhadap keberhasilan usaha sedangkan sisanya 37,3% dijelaskan olehvariabel lain diluar variabel penelitian. Hasil analisis uji F diperoleh Fhitung 14,419 > Ftabel1,717 dengan tingkat signifikansi 0,000 < 0,05. Hal ini menunjukkan bahwa pengetahuankewirausahaan, karakteristik kewirausahaam dan kompetensi kewirausahaan secaragabungan berpengaruh terhadap keberhasilan usaha.
Pengaruh Kecerdasan Emosi, Komitmen Organisasi dan Quality of Work Life (QWL) terhadap Kepuasan Kerja serta Implikasinya terhadap Organizational Citizenship Behavior (OCB) pada Wanita Pekerja Profesional Di Wliayah Jakarta.
Authors: Suryani Rahayu Endang
Published: November 2022

Tujuan penelitian untuk menguji dan menganalisis pengaruh kecerdasan emosi, komitmenorganisasi dan quality of work life (qwl) terhadap Organizational Citizenship Behavior (OCB) melaluikepuasan kerja pada Wanita Pekerja Profesional Di Wliayah Jakarta baik secara parsial maupun bersamasama.Penelitian menggunakan metode deskriptif dengan teknik survey. Instrumen penelitianmenggunakan kuesioner tertutup dengan skala Likert. Analisa Data Deskriptif diolah dengan programSPSS versi 24. Analisa data inferensial menggunakan model Structural Equation Modelling (SEM)dengan program Lislrel 8.72. Populasi penelitian sebesar 19.286 wanita pekerja profesional di Jakarta.Melalui teknik slovin (α=5%) diperoleh sample sebesar 392. Teknik pengambilan sample menggunakansimple random sampling.Hasil penelitian menunjukkan bahwa kecerdasan emosi, komitmen organisasi dan quality of worklife (qwl) secara bersama-sama memberikan kontribusi sebesar 80% terhadap Kepuasan Kerja padawanita pekerja profesional di Jakarta. Secara parsial, kecerdasan emosi memiliki pengaruh yang palingdominan terhadap kepuasan kerja. Hasil penelitian juga menunjukkan bahwa kecerdasan emosi,komitmen organisasi, quality of work life (qwl) dan kepuasan kerja secara bersama-sama memberikankontribusi sebesar 92% terhadap organizational citizenship behavior (ocb) pada wanita pekerjaprofesional di Jakarta. Secara parsial, kecerdasan emosi memiliki pengaruh yang paling dominanterhadap organizational citizenship behavior (ocb).Temuan lain dari penelitian ini adalah kepuasan kerja berperan sebagai parsial mediating bagikomitmen organisasi dan quality of work life (qwl) untuk meningkatkan Organizational CitizenshipBehavior (OCB). Sedangkan kecerdasan emosi tidak memerlukan mediasi variabel kepuasan kerja untukmeningkatkan Organizational Citizenship Behavior (OCB).
Perkembangan Rumah Sakit Modern dengan Paradigma Lean Thinking
Authors: Kennedy Posma S Ariguna Johnson , Fitranto Aswin Griksa , Pare Sri
Published: November 2022

Dalam perjalanannya, perkembangan konstruksi untuk peningkatan kesehatan masyarakat banyakmengalami perubahan. Studi ini merupakan bagian dari penelitian rancang bangun rumah sakit modern,karena itu perlu ditelusuri perkembangan desain rumah sakit sehingga dalam perencanaannya dapat lebihefisien dengan berbagai perubahan paradigma yang terjadi. Pada studi ini dikaji juga perbedaan metode desaintradisional dengan modern yang kini mengedepankan lean thingking (perampingan/efisiensi) dalammendesain rumah sakit. Studi ini menggunakan metode penelitian dengan pendekatan kualitatif. Denganmempelajari berbagai dokumen dan literatur dikaji perkembangan arsitek tradisional sampai dengan modern.Dimana kini lean thingking perlu diperhatikan dalam mendesain rumah sakit modern.
Karakteristik dan Periode Ulang Tinggi Gelombang Laut di Laut Banda pada Monsun Timur
Authors: Azhari Ferian , Kurniawan Muhammad Azis , Pranowo Widodo Setiyo , Widodo Kukuh Suryo , Purwanto Budi
Published: November 2022

Indonesia merupakan negara kepulauan yang sebagian besar wilayahnya adalah lautan, oleh karena itu segala aktivitas di laut seperti pelayaran dan penangkapan ikan merupakan bagian penting bagi masyarakat Indonesia. Indonesia memiliki perairan yang startegis dikarenakan letaknya berada diantara benua Asia dan Australia. Ada beberapa wilayah laut yang sangat menarik di Indonesia, salah satunya yaitu laut Banda. Lokasi penelitian terletak di perairan Laut Banda dengan batas koordinat 30 LS – 80 LS dan 1240 BT – 1320 BT dengan menggunakan 187 titik stasiun pengamatan dengan jarak antar stasiun 0.250. Dari lokasi penelitian tersebut akan dikumpulkan data gelombang yang akan digunakan untuk menentukan karakteristik dan peramalan periode ulang tinggi gelombang di lokasi penelitian. Data yang dipergunakan dalam penelitian ini adalah data ERA5 ECMWF dari tahun 2012 sampai dengan 2021. Data yang diunduh berupa data tinggi gelombang signifikan, tinggi gelombang maksimal, periode gelombang  dan arah gelombang yang memiliki resolusi spasial 0,250 dan temporal 1 jam. Tinggi gelombang maksimal dan tinggi gelombang signifikan tertinggi dari 2012 sampai dengan 2021, terjadi pada bulan Juni tahun 2019 dengan tinggi gelombang signifikan mencapai 3,51 meter dan tinggi gelombang maksimal mencapai 6,72 meter. Rata-rata perioda gelombang tertinggi dari 2012 sampai dengan 2021, terjadi pada bulan Juni tahun 2019 dengan perioda gelombang 5,38 detik dengan arah dari Tenggara. Prakiraan tinggi gelombang signifikan pada tahun 2023 mencapai 2,864 meter dengan batas atas 3,025 meter dan batas bawah 2,703 meter.
INVESTIMENTOS PRIVADOS EM INFRAESTRUTURA E A IMPORTÂNCIA DA QUALIDADE E ESTABILIDADE REGULATÓRIA
Authors: Rocha Katia
Published: November 2022

A infraestrutura inadequada é uma das principais barreiras ao crescimento econômico brasileiro. Há certo consenso de que somente o investimento público não seria suficiente para aumentar o estoque e a qualidade da infraestrutura brasileira a níveis adequados. O Brasil precisaria, portanto, melhorar a eficiência do investimento público e, ao mesmo tempo, gerar as condições necessárias para incentivar e mobilizar o investimento privado em escala e ritmo necessários. Diversos estudos evidenciam que melhores níveis de qualidade regulatória estão associados a maiores investimentos privados em infraestrutura, e quantificar essa relação é fundamental para o formulador de políticas públicas. Se o Brasil se aproximasse da nota média de qualidade regulatória observada nos países da Organização para Cooperação e Desenvolvimento Econômico (OCDE), quais seriam os impactos nos fluxos de investimentos privados em infraestrutura no país? Esse artigo tenta responder essa questão a partir de dados sobre investimento privado em infraestrutura nas economias emergentes e respectivos rankings de qualidade regulatória.
SUBVENÇÃO ECONÔMICA: ESTATÍSTICAS DOS PERÍODOS RECENTES
Authors: Zucoloto Graziela , Koeller Priscila
Published: November 2022

A análise da subvenção econômica no período das duas últimas Estratégias Nacionais de Ciência, Tecnologia e Inovação – ENCTI (2012-2015 e 2016-2022) parece indicar que não houve respostas adequadas às críticas de estudos que avaliaram a implementação do instrumento em anos anteriores. Ao contrário, parece ter havido “acirramento” de problemas como: redução do tempo de vigência e do porte dos projetos e diminuição dos percentuais de contrapartida das instituições proponentes. Essa análise acende um alerta para os próximos anos em que será possível contar com recursos estáveis para subvenção em virtude da aprovação da Lei Complementar no 177/2021.