bluuebunny/crossref_metadata_2025 huggingface dataset:
Normative approaches in drug providing servicemen with thoracoabdominal injury
Authors: Shmatenko O. P. , Trohymchuk V. V. , Solomennyy A. M.
Published: September 2019

One of the urgent problems of health care institutions Health and Medical Service of the Armed Forces of Ukraine is to find ways to streamline the logistics of medical institutions in accordance with their needs. Implementation of the principles of rational use of material resources in the scientific, organizational, medical and medical-technological levels increases the cost-effectiveness of medical supplies. An analysis of the functional characteristics of the formulary system found that it actually uses the traditional approach rationing drugs.

The aim of the research is to develop methods of rationing drugs for medical software affected servicemen with thoracoabdominal injury. Objects of study: accounting and reporting documents of military medical clinical centers in the region for five years. Subject of research: methodological approaches, regulations and organizational and economic foundations of the system of medical provision affected servicemen with thoracoabdominal injury. Methods: statistical and normative.

The study established a valuation technique medicines to provide specialized medical care for victims with thoracoabdominal trauma servicemen at military medical clinical centers of the Ministry of Defense of Ukraine, as well as the rationale for the rules implemented drugs per injured serviceman with thoracoabdominal trauma, ten beds and per specialist doctor profile office.
Synthesis, physical and chemical properties of 5-(phenoxymethylene)-4-R-1,2,4-triazol-3-thiones derivatives, which contain alkyl- and arylnitrile fragments
Authors: Kucheryavyi Yu. M. , Kaplaushenko A. G.
Published: September 2019

Ukraine takes the second place in Europe for the dissemination of cancer. Ukrainian pharmaceutical market practically doesn’t have domestic anti-tumor drugs. That’s why, many scientists of pharmaceutical industry work in this direction.  The searching of biologically active substances among derivatives of 1,2,4-triazole is actually for today. Anastrozole and Letrozole are enough known like anti-tumor drugs which contain in their structures the core of 1,2,4-triazole and nitrile groups.

The aim of our work is purposeful synthesis a number of new highly effective compounds 2-((5-(phenoxymethylene)-4-R-4H-1,2,4-triazole-3-yl)thio)acetonitriles and

2-, 3-, 4-(((5-(phenoxymethylene)-4-R-4H-1,2,4-triazole-3-yl)thio)methyl)benzo-nitriles, research of its physical and chemical properties.

The 5-(phenoxymethylene)-4-R-1,2,4-triazole-3-thiones, which contain alkyl- and arylnitrile groups has been synthesized and its effective methods obtaining have been set. The structure of synthesized compounds has been confirmed by modern complex of physical and chemical methods of analysis.

The synthesized compounds with alkyl- and arylnitrile functional groups will become the basis for further modification of the structure to increase results or expand the range of the biological activity.
The studing of antimicrobial activity of 4-(R-ylidenamino)-3-( morpholinomethylene)-4H-1,2,4-triazole-5-thiol
Authors: Shcherbyna R. О. , Panasenko O. I. , Knysh Ye. H. , Kamyshnyy O. M.
Published: September 2019

According to the information of the World Health Organization (WHO) the lethal cases caused by pathogenic microorganisms occupied the one of the leading places. Most acutely the problem posed in countries where economic opportunities does not hold the flashes of infectious diseases under control. Therefore necessity of the new, available and high bactericidal drugs is reasonable and justified. Unfortunately, in literary sources missing information which devoted to 4-(R-ylidenamino)-3-(morpholinomethylene)-4H-1,2,4-triazole-5-thioles.

The main aim of our work are studying antimicrobial and antifungal properties of 4-(R-ylidenamino)-3-(morpholinomethylene)-4H-1,2,4-triazole-5-thioles  by serial dilutions method and establishing some patterns dependence "structure-action". The research was conducted by using of standard test cultures:  Staphylococcus aureus, Escherichia coli, Pseudomоnas aeruginosa, Candida albicans. The trimethoprimum was used as reference preparation for antimicrobial activity studying, the nystatinum – for antifungal.

Thus, the most pronounced antimicrobial action during the experiment shows 3-(morpholinomethylen)-4-(((5-nitrofuran-2-yl)methylene)amino)-4H-1,2,4-triazole-5-thiol (2.18) and 3-(morpholinomethylen)-4-((3-(5-nitrofuran-2-yl)allylidene)amino)-4H-1,2,4-triazole-5-thiol (2.19) which exceeds the standard comparison drug trimethoprimum. The researching of compounds 2.1–2.21 has specified the absence of pronounced antifungal properties for a reference strain of C. albicans. Some regularities of the influence structure of tested substances for the pharmacological activity were established, and they can be useful in future searching of highly effective antimicrobial drugs.
Comparative analysis of medications for local treatment of burns on national and foreign markets
Authors: Vons В. V. , Chubka M. B. , Groshovyi T. A. , Stechyshyn I. P.
Published: September 2019

Burn wound treatment issues remain relevant in modern medicine, since burns are among the most common types of injuries and rank third among all types of injury in peacetime. The problem of treatment of burn injuries are determined by the high frequency of their occurrence, the complexity and duration of treatment of such patients, with serious consequences.

To date, in the world there are a large number of drugs for local treatment of burns in various forms (ointments, gels, creams, aerosols, solutions for external use, patches) and biological drugs are also used.

The aim of the work was to conduct a comparative analysis of the range of registered medicinal products for local treatment of burns on the national market, with preparations of this segment of the market, registered in Georgia and France. Georgia is a country, which is not a member of the European Union, and France is one of the five countries leading exporters of medicines and is a member of the European Union, in order to determine the relevance and feasibility of developing new drugs. In the analysis of drugs registered in the pharmaceutical markets of France and Georgia, those drugs that have no analogues in Ukraine, for the most part are patches (patches), considering in more detail.

The study of the nomenclature assortment of drugs carrying out in accordance with the State Register of drugs and the Anatomical-Therapeutic-Chemical Classification, as an information source was used Compendium, online-directories and online-pharmacу.

According to the results of the research conducted on the end of 2018, in Ukraine there are about 105 drugs, production in various forms that is directly used for local treatment of burns. In the pharmaceutical markets of Georgia and France, this amount of drugs is respectively 101 and 64 drugs. In all three countries, most medications for local treatment of burns presented in soft drugs, in particular, in Ukraine 67.58%, in Georgia 84.16% and in France 39.06%, respectively. In Ukraine, 58.33% of all drugs for local treatment of burns domestically produced, but in Georgia and France, the proportion of such drugs is significantly lower, namely 11.88% and 32.81% respectively.

The comparative analysis conducted by us proved that in the pharmaceutical markets of France and Georgia there were registered drugs in the form of patches that are widely used in the treatment of burn injuries, the analogues of which are absent in Ukraine.

These studies prove the prospect of expanding the range of existing ursus forms and creating a new group of original drugs that would stimulate regenerative skin processes and improve wound healing.
Scientific methodology and practical use of managed entry agreements for innovative medicines in system of health technology assessment in Ukraine
Authors: Zaliska O. M. , Stasiv KH.-O. J.
Published: September 2019

In the Health Technology Assessment (HTA) system, it is advisable to use a mini-HTA to save budget funds at the hospital level, taking into account real world data on drug consumption for a rational use of resources at the local level. HTA include Managed Entry Agreements (MEA), which is being actively implemented in Europe to ensure the availability of innovative medicines for the treatment of oncological, hematological, rare diseases, assisted reproductive technologies (ART), and government funding programs.

The aim of this study was to analyze the use of the mini-HTA approach for the evaluation of innovative drugs, in particular with ART. Theoretically and practically substantiate the «Managed Entry Agreement» methodology for innovative drugs for rapid availability to new medicines based on evidence-based medicine and pharmacoeconomics for implementation at the state (local) level and rational use of budget funds.

Research methods – systematic analysis of data of reports, publications about the mini-HTA and the «Managed Entry Agreement» in the leading countries of Europe. The main objects were articles, reviews of pharmacoeconomists of ISPOR, LSE, which are leading in the HTA field in the world. The statistical data on innovative drugs, included in the legislatively regulated by the MEA in the EU, Central and Eastern Europe countries, using the methods of generalization, systematic analysis were studied.

We summarized the HTA data include in mini-HTA reports in EU countries, which were legally regulated and included innovative drugs for the treatment of cancer, hematological and rare diseases. We established that using 6 main MEA methods, regulated by law in the EU countries. There is necessary to create a recommendation on mini-HTA and MEA to improve the regulatory framework and activities of the HTA Department of State Expert Centre, MoH of Ukraine in order to implementation of the State strategy for implementing the State policy of providing the population with medicines for the period up to 2025.

We formulated the term «mini-HTA» as a systematic process of evaluating indicators of effectiveness, safety, quality of life, social and ethical aspects in relation to the costs for innovative drugs to save budget resources at the local level. There is advisable to use the MEA methods to estimate the cost for treatment regimens, including drugs for ART, which will ensure the rational use of funds for state programs, in particular, for the treatment of infertility, and public health resources.
Anticonvulsant activity of 5-(furan-2-yl)-4R1-1,2,4-triazole-3-thione S-derivatives
Authors: Parchenko V. V.
Published: September 2019

Among the huge number of drugs registered in Ukraine anticonvulsants occupy a special place. They are mainly used for the relief of different etiology seizures. Along with the principal pharmacological action of drugs in this group there were exhibited a number of unwanted side effects. Therefore the question of the searching for new biologically active molecules, remains relevant today and is necessary for the further practical introduction into medical practice.

The purpose of our work was to study the anticonvulsant activity of 5- (furan-2-yl) -4R1-1,2,4-triazole-3-thione S-derivatives.

The anticonvulsant activity study of the 5-(furan-2-yl)-2H-1,2,4-triazole-3-thione S-derivatives and 5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazole-3-thiones were conducted on the test of interaction with agents that stimulate the central nervous system. The theoretical computer predictions indicate the prospects in searching among the represented compounds classes. The criteria for assessing anticonvulsant activity were the changings in attack seizures latency and their duration. Reference drugs were Mydocalmum and Phenobarbital. Among the studied substances two compounds had the highest activity which is equivalent in strength to the activity of reference drugs.

Two compounds among the studied substances have the highest activity which is equivalent in strength to Mydocalm activity/ Also 2-[5-(furan-2-yl)-4-fenil-4H-1,2,4-triazole-3-ylthio]-1-(4-chlorfeniletanon) must be noted, whose activity exceeds the activity of Phenobarbitalum and Midokalm in 1,23 and 1,27 times respectively on korazol model of seizures in rats. For some classes of 1,2,4-triaxole-3-thione 5-furanderivatives there were established structure–action patterns.
Chromato-mass-spectrometric assessment of volatile components for nettle (Urtica dioica L.)
Authors: Smoylovskaya G. P.
Published: September 2019

The species of nettle (Urtica dioica) are used long ago as hemostaticum for hemorrhages of various genesis both in non-traditional and in official medicine. Besides, the extractions of nettle possess hypolipidemic, cholagogue, anti-inflammatory, spasmolytic, prostatoprotective, adaptogenic properties, etc. Biologic activity of the nettle (Urtica dioica) is conditioned by the presence of various vitamins, carotenoids, proteins, flavonoids, hydroxycinnamic and organic acids, β-cytosterol, volatile compounds and other components.

The aim of our study was to investigate the qualitative and quantitative composition of the volatile content of nettle.

The research has been done on aero-dried vegetable raw-material Urtica dioica L. (leaves), stocked in June 2014 in Zaporizhzhya region. Identification and assessment of a number for volatile components has been done on the chromatograph Agilent Technology 6890 N with mass-spectrometric detector 5973.

Approximately 20 components have been revealed in the leaves of Urtica dioica: hexahydrofarnesilacetate (165,19 mc/kg) and squalene (99,59 mc/kg) are predominated. Phytol, 2-methoxy-4-vinylphenol, nonacosane, etc. are presented in lesser number. The content of chrysanthenone, p-cymen-8-ol, verbenone, nerolidol, caryophyllene oxide, tricosane, tetracosane, heptacosane and untriacontane was insignificant (1,9% of the total amount of volatile components). Total number of volatile components in the leaves of Urtica dioica was 498,61 mc/mg. The research of qualitative composition and a number of volatile components in the leaves of Urtica dioica growing in Ukraine demonstrate expediency to carry out the further researches on the species Urtica dioica for using them in elaborating phytodrugs of complex action.
Daftar Isi Vol. 3 No. 2 2019
Authors: JSHP Jurnal
Published: September 2019

Puji dan syukur kita panjatkan kehadirat Allah SWT, karena atas berkat dan rahmat-Nya Jurnal Sosial Humaniora dan Pendidikan (JSHP) Volume 3 Nomor 2 Tahun 2019 dapat diterbitkan oleh Pusat Penelitian dan Pengabdian kepada Masyarakat (P3M) Politeknik Negeri Balikpapan.JSHP diterbitkan secara berkala sebagai wadah publikasi hasil penelitian dan karya ilmiah dibidang Sosial, Humaniora dan Pendidikan Tinggi yang dilakukan oleh dosen dan peneliti baik internal Politeknik Negeri Balikpapan serta insan akademik dari perguruan tinggi lain.Dengan terbitnya JSHP ini secara berkala semoga dapat meningkatkan motivasi dan produktivitas dosen dan peneliti di Kota Balikpapan dan sekitarnya untuk lebih banyak menghasilkan karya-karya penelitian yang bermanfaat dan menjawab kebutuhan masyarakat. Disamping itu JSHP ini semoga dapat menjadi sumber referensi untuk kegiatan penelitian serta dapat memperkaya bahan ajar bagi kegiatan belajar mengajar di Kampus Politeknik Negeri Balikpapan dan kampus lainnya. Penerbitan JSHP Vol 3 No 2 2019 mengalami kemunduran terbit dikarenakan dalam proses penyempurnaan tampilan website dan proses review artikel yang baru selesai. Kedepan semoga lebih tepat waktu.Akhirnya redaksi JSHP mengucapkan selamat dan terimakasih pada para dosen/peneliti yang telah berkontribusi dalam penerbitan JSHP  Vol 3 No 2 2019.                                                                                                 Balikpapan, 10 September 2019                                                                                                Hormat Kami                                                                                                                                                                                             Redaksi JSHP
Financeirização do Meio Ambiente
Authors: Salviatti Ana Paula
Published: September 2019

O artigo a seguir propõe uma análise sobre a abordagem oferecida pela economia neoliberal para as políticas voltadas para o cenário ambiental e o desenvolvimento das nações ajustadas, então entendido como desenvolvimento sustentável. Para tanto, o fio condutor deste trabalho será o desenvolvimento internacional da economia política das últimas décadas, dimensão na qual ocorreram reacomodações na divisão internacional do trabalho. Dentro do proposto, se destaca a maneira pela qual problemática ambiental recebe tratamento semelhante às outras esferas submetidas à lógica do capitalismo, e resultante desta operação o Protocolo de Quioto figura como a solução melhor adaptada às necessidades da reprodução capitalista em pleno regime de acumulação financeirizado
Поширення Origanum vulgare (Lamiaceae) на рівнинній частині України в голоцені
Authors: БЕЗУСЬКО ЛЮДМИЛА ГЕРАСИМІВНА , ЦИМБАЛЮК ЗОЯ МИКОЛАЇВНА
Published: September 2019

У статті надано узагальнення даних палеопалінологічних досліджень по визначенню пилку представників родини Lamiaceae у складі палінологічних характеристик як поверхневих проб ґрунтів, так і відкладів плейстоцену-голоцену рівнинної частини України. Встановлено, що зазвичай у викопному стані пилок Lamiaceae був ідентифікований до рівня родини. Дуже рідко у складі викопних палінофлор трапляються пилкові зерна, які були визначені до родового та видового рівнів. У публікації наводяться результати видової ідентифікації пилкових зерен О. vulgare у складі палінологічних характеристик відкладів голоцену 10 розрізів Лісової, Лісостепової та Степової зон України. Вперше за узагальненими матеріалами комплексних палеофлористичних та радіовуглецевих досліджень обґрунтовано та реконструйовано просторово-часову диференціацію поширення О. vulgare у голоцені. З використанням світлового і сканувального електронного мікроскопів досліджено пилкові зерна O. vulgare флори України. Встановлено, що пилкові зерна 6-борозні, еліпсоїдальні або сплющено-сфероїдальні, зрідка сфероїдальні за формою, в обрисах з полюса 6-лопатеві, з екватора еліптичні, зрідка округлі; середніх розмірів. Борозни майже однакові за довжиною, вузькі, з чіткими краями та більш-менш загостреними кінцями. Чотири мезокольпіуми переважно вужчі, а два інших – ширші. Скульптура екзини чітка, подвійно сітчаста, борозні мембрани гладенько-гранулярні. Показано, що виявлені діагностичні ознаки пилкових зерен O. vulgare можна використовувати для їхнього точнішого визначення у викопному стані до видового рівня при проведенні спорово-пилкового аналізу відкладів плейстоцену-голоцену України та прилеглих територій.
Класифікація лісової рослинності національного природного парку «Кармелюкове Поділля» (Вінницька область, Україна)
Authors: МАРКІВСЬКА ЛЮБОВ ВОЛОДИМИРІВНА , ЯВОРСЬКА ОЛЕНА ГРИГОРІВНА , КУЗЕМКО АННА АРКАДІЇВНА
Published: September 2019

На основі 147 геоботанічних описів лісової рослинності, зібранних упродовж 2006–2017 років і оброблених у програмному пакеті Juice за допомогою різних методів кластерного аналізу, проведено класифікацію рослинності широколистяних лісів Національного природного парку «Кармелюкове Поділля» за методом Браун-Бланке. Запропонована класифікаційна схема включає три асоціації, три субасоціації, п’ять варіантів та одне безрангове угруповання, що належать до двох класів рослинності – Carpino-Fagetea sylvaticae і Quercetea pubescentis. Клас Carpino-Fagetea sylvaticae представлений двома асоціаціями Galeobdolono lutei-Carpinetum і Isopyro thalictroidis-Carpinetum. Перша асоціація представлена на території парку субасоціацією sambucetosum nigrae і відзначається значно більш вираженою внутрішньою диференціацією, оскільки включає три варіанти, що формуються в умовах різного антропогенного навантаження. Клас Quercetea pubescentis представлений на території парку однією асоціацією Quercetum pubescenti–roboris, для якої описано нову субасоціацію quercetosum petraeae з двома варіантами, що характеризуються різними мікрокліматичними особливостями. За результатами фітоіндикаційної оцінки виділених синтаксонів встановлено, що едафічні фактори відіграють значно більшу роль у їх диференціації, ніж кліматичні. Серед едафічних факторів найбільший вплив на диференціацію синтаксонів мають ті, що зумовлюють багатство ґрунтів – сольовий режим ґрунту та вміст засвоюваних форм азоту в ньому. У складі дослідженої рослинності виявлено 16 видів, занесених до діючого видання Червоної книги України, найбільш поширеними з яких є Sorbus torminalis, Allium ursinum i Viola alba. Досліджені фітоценози лісової рослинності парку є типовими для південно-східного Поділля, однак вони мають риси подібності з дубовими та грабово–дубовими лісами Центрального та Західного Поділля, а також Правобережного Придніпров’я. Лісова рослинність займає більшу частину території НПП «Кармелюкове Поділля», вона характеризується досить високим флористичним і ценотичним багатством, а також значною природоохоронною цінністю, зумовленою суттєвою участю рідкісних та зникаючих видів.
Мохоподібні Смарагдової мережі України під охороною Бернської конвенції
Authors: БОЙКО МИХАЙЛО ФЕДОСІЙОВИЧ
Published: September 2019

У статті дано характеристику видів мохоподібних, які включені до Додатку І Бернської конвенції, що була прийнята у 1979 р. та зустрічаються у бріофлорі України. Це такі види, як Dicranum viride (Sull. & Lesq.) Lindb. (Dicranaceae), Dichelyma capillaceum (With.) Myrin (Fontinalaceae), Buxbaumia viridis (Mougeot ex Lam. & DC) Mougeot & Nestler, 1823 (Buxbaumiaceae), Meesia longiseta Hedw. Meesiaceae), Hamatocaulis (Drepanocladus) vernicosus (Mitt.) Hedenäs (Amblystegiaceae), Mannia triandra (Scop.) Grolle (Aytoniaceae). Вказується українська та латинська назви виду, код виду із Стандартної форми даних Смарагдового об’єкта, їх біогеографічний регіон, загальна характеристика виду, родина, наукова цінність, загальний ареал, поширення виду в Україні з вказівкою фізико-географічних зон та гірських ландшафтних країн України (Українські Карпати (Закарпаття, власне Карпати, Прикарпаття), Крим (Гірський Крим, Південнобереговий Крим), Українське Полісcя, Неморальна зона (в т.ч. Опілля, Розточчя, Західний Лісостеп), Лісостепова зона, Степова зона (в тому числі Степовий Крим), місцезнаходження, умови місцезростання, фотографічне зображення виду, головні фактори зменшення чисельності популяцій видів, прийняті заходи охорони з вказівкою кодів Смарагдових об’єктів, у яких зберігається вид, необхідні заходи охорони та список використаних джерел. Отже, у зв’язку з актуальністю вивчення видів рослин, в тому числі несудинних, які включені в додатки Бернської конференції та проектуванням природоохоронної мережі Емеральд (Смарагдової мережі) України, необхідно посилити дослідження популяцій цих рідкісних видів та біотопів, у яких вони зростають. Особливо це важливо щодо видів мохоподібних, оскільки знахідки більшості з них були зроблені досить давно. Матеріали сучасних досліджень дадуть можливість реального відображення стану популяцій видів у природоохоронній екологічній мережі з метою їх дієвої охорони.
Анотований список флори проектованого ботанічного заказника «Старошведський» (Херсонська область, Україна)
Authors: МОЙСІЄНКО ІВАН ІВАНОВИЧ , ДАЙНЕКО ПОЛІНА МИХАЙЛІВНА , ЗАХВАТОВИЧ МАРІЯ , ДЕМБІЧ ІВОНА , СУДНІК-ВОЙЦИКОВСЬКА БАРБАРА
Published: September 2019

Проектований ботанічний заказник місцевого значення «Старошведський» планується створити на землях Зміївської та Червономаяцької сільських рад Бериславського району Херсонської області. Пропонована назва заказника пов'язана з існуванням тут шведської колонії, починаючи з кінця XVIII століття. Заказник планується створити на території площею 263 га, що включає 2 балки (Костирську і Широку) та 3,5 км тераси Дніпра між ними. Територія проектованого заказника характеризується досить високим різноманіттям природних умов; окрім домінуючих степових оселищ тут представлені луки, чагарникові зарості, штучні лісові насадження, відслонення вапняків, лесів та глин, а також кліф, узбережжя та акваторія водосховища та рудеральні оселища. Анотований список флори судинних рослин проектованого ботанічного заказника «Старошведський» включає 359 видів судинних рослин, що відносяться до 222 родів, 68 родин, 3 класів та 2 відділів. Високе представництво аборигенних (279 видів, або 77,7 %), степових (171 вид, або 44,8 %) та несинатропних (123 види, або 34,2 %) рослин вказує на досить добрий рівень збереженості природних комплексів об’єкту, що створюється. Проектований заказник має високу созологічну цінність на регіональному, національному та міжнародному рівні. На регіональному рівні його природоохоронне значення репрезентують 10 видів рослин, що включені до Червоного списку Херсонської області (Amygdalus nana, Bellevalia sarmatica, Bromopsis heterophylla, Ephedra distachya, Hyacinthella leucophaea, Jurinea stoechadifolia, Poa sterilis, Quercus robur, Vinca herbacea та Vitis sylvestris). Висока созологічну цінність національного рівня зумовлена зростанням тут 10 видів рослин, що занесені до Червоної книги України (Astragalus dasyanthus, A. ponticus, Elytrigia stipifolia, Ornithogalum boucheanum, Stipa capillata, S. lessingiana, S. pulcherrima, S. ucrainica, Tulipa biebersteiniana та T. gesneriana) та 6 рослинних угруповань, включених до Зеленої книги України (Amygdaleta nanae, Elytrigieta stipifoliae, Stipeta capillatae, Stipeta lessingianae, Stipeta pulcherrimae та Stipeta ucrainicae). Созологічне значення на міжнародному рівні зумовлене зростанням тут рослини, що включена до Резолюції № 6 (Додаток 1) Бернської конвенції та Додатку ІІ Оселищної директиви ЄС – Jurinea cyanoides; також тим, що більшість території проектованого заказника є оселищами Резолюції № 4 Бернської конвенції (E1.2 Багаторічні трав’яні кальцифітні угруповання та степи та F3.247 Понтично–сарматські листопадні чагарникові зарості). Ці ж оселища під дещо іншими назвами включені до Додатку І Оселищної директиви ЄС. Враховуючи високу созологічну цінність даної території необхідно створити тут ботанічний заказник місцевого значення «Старошведський».
Pengetahuan dan Sikap Lansia tentang Penggunaan Obat Tradisional Hipertensi
Authors: Awaluddin Awaluddin , Purwanto Purwanto
Published: September 2019

The used of traditional medicines to decrease hypertension were increased. The used of them were influenced by knowledge and attitude. The purpose of this study was to known the correlation of knowledge and attitude of the elderly in use of the traditional medicine to reducing hypertension in Batang Tumu Health Center, District of Indragiri Hilir. This study was analytical withcross sectionaldesign. The population were all elderly who had hypertension as many as 143 respondent. The number of samples in this study were 59 respondents. The technique of sampling was purposive. Measuring instrument used was questionnairre. The results showed that elderly with well knowledge were 31 respondents (52.2%) and positive attitude were 38 respondents (64.4%). The chi square test results showed that there was a significant correlation between knowledge with the use of traditional medicine to reduce hypertension with p value 0.002<alpa 0.05. There was a significant correlation between elderly attitude with the use of traditional medicine to reduce hypertension with p value 0.004 <alpa 0.05. This result of study had implication to nursing that needed good knowledge and positive attitude for elderly so that can be use hypertension traditional medicine.
Magnitude of electric burns at a burn center in tertiary level hospital
Authors: Islam Md Tarikul , Rahman Mizanur , Nayeem SM Zulker , Uddin Md Farid
Published: September 2019

Background: Burns are a public health problem throughout the world. Electrical injury is a major cause of burn injury which causes significant functional disability, disfigurement and mortality. In Bangladesh, the number of electrical injuries are increasing but they are typically underreported.

Aims: This study was conducted to analyze the epidemiological variables of electrical burn injuries and identify preventable measures through them in Khulna region of Bangladesh.

Methods: This descriptive study is a prospective analysis of patients suffering from electrical burns admitted at Burn and plastic surgery department from July 2017 to June 2018. The study population consists of 68 patients who sustained electrical injuries irrespective of age and time with cutaneous burns, admitted at this Center. Patients with electrocution but no electrical cutaneous burn injuries were excluded from this study.

Results: Majority were males (77.94%) of working age and injuries were work related (52.94%) of which 32.36% were construction workers. The primary cause in majority of the cases (57.35%) was accidental direct contact with electric wire followed by secondary contact with electrical power lines by metal rods and electrification of different metallic equipments (42.64%). Most of the patients admitted were high voltage electrical injuries (54.42%). Among them 16.17% had severe electrical burns and 2.94% had associated traumatic injuries. There was a delay in time of injury to hospital admission, 35.29% arrived at the emergency room 8 or more hours after the injury. Most (63.24%) of the patients underwent surgery, majority of which had moderate to severe burns. Length of hospital stay was 3-102 days. Two patients (2.94%) died during this study period due to renal failure and septicaemia.

Conclusion: Most of the electric burn patients acquired injury at working place and primary cause was direct or secondary contact with powerline. Immediate preventive measures should be taken to reduce the incidence of electric burns.

Bang Med J (Khulna) 2018; 51 : 29-34
Institutional Isomorphism & the Rise of a Hybrid Model in Education Philanthropy
Authors: Sands Sara
Published: September 2019

In this paper, I draw upon a theoretical framework informed by institutional isomorphism (DiMaggio & Powell, 1983) to analyze the grantmaking practices of traditional and strategic philanthropies, with particular attention to areas of increasing convergence such as the utilization of measurable outcomes and metrics. Drawing on interviews with foundation officers and grant information from Foundation Directory Online, I find that while differences remain between traditional and strategic philanthropies, a new “hybrid philanthropy” model is emerging that blends outcomes-oriented and field-oriented approaches to grantmaking. I also find that the homogenization of practices across foundations and the influence of larger policy trends focused on data-driven decisionmaking may be leading foundations to exercise what might be termed “high stakes grantmaking.” To the extent that this might conflict with what is good for students and communities, and the goals of democratic decision making in education policy more broadly, additional research is needed.
Beatlab: How a Hip-Hop Digital Space Became an Outlet for Political Dialogue
Authors: Carroll Jeffrey
Published: September 2019

This paper explores the implications of a project called “Beatlab,” a digital music studio that was created at Chestnut Hill College as a gathering place to craft music (beats) and write personal reflections (rhymes). I document how Beatlab emerged as a safe space for expression and self-exploration and in turn, became a hub for conversation around complex political issues for the College and beyond.
A Re-Interpretation of the Normative Foundations of Majority Rule
Authors: Prasad Mahendra
Published: September 2019

There are four standard normative defenses for majority rule on two alternatives: fairness (i.e., May's theorem), epistemic (i.e., Condorcet's jury theorem), utilitarian (i.e., Rae-Taylor theorem), and contractarian (i.e., maximization of the number of self-determined voters). There are many ways to generalize majority rule to multiple alternatives, but the standard generalization is majority preference (i.e., Condorcet method). Unfortunately, these arguments fail to generalize to multiple alternatives due to Condorcet's paradox. In this paper, I generalize each of those four defenses to multiple alternatives using the consent of the majority generalization (e.g., approval voting) of majority rule. For example, I show that among Arrovian voting systems, an Arrovian version of approval voting is the voting system with the least restrictive domain which satisfies May's theorem's four conditions, and independence of irrelevant alternatives. The findings suggest that we should normatively and formally explore multiple interpretations of majority rule, beyond majority preference.
Epidemiology of contact lens-induced giant papillary conjunctivitis: a retrospective study
Authors: Myagkov Alexander , Dyomina Elena , Forbes Valery
Published: September 2019

Purpose: The purpose of the study is to determine the correlation between the incidence of giant papillary conjunctivitis induced by the use of contact lenses (CLPC) and contact lens material, replacement schedule or wearing time. The emergence of new materials and designs of contact lenses along with modifications in the replacement and wearing schedule have changed the structure of complications in users of soft contact lenses (SCLs). At present, infectious and hypoxic complications are extremely rare; on the other hand, toxic-allergic reactions that arise in users of contact lenses (CLs) have come to the fore.
Material and methods. A retrospective cohort clinical study involved 1 668 users of SCL of various materials and with different replacement and wearing schedules. Patients were monitored from 2008 to 2018.
Results. As a result of the study, it was found that the CLPC incidence correlate with the wearing time and replacement schedule of the SCLs.
The use of tear substitutes when wearing contact lenses (literature review)
Authors: Mits Artur
Published: September 2019

Topicality. In recent years, dry eye syndrome has become increasingly important in clinical practice. Disturbance of the wettability of the eye surface occurs due to external factors influence, one of which are contact lenses. The review presents the literature data analysis covering possible impact of contact lenses made of different materials (hydrogel, silicone hydrogel, soft and rigid gas permeable) on the development of dry eye symptoms, as well as the role of tear substitutes use when wearing contact lenses. Due to agreat variety of different studies on this topic, the literature review on the tear substitutes instillation when wearing contact lenses in patients with dry eye syndrome is relevant and crucial for doctors in outpatient departments.
Conclusion. The research has shown that, it is possible to identify unmodifiable and modifiable risk factors for dry eye syndrome with reliable and probable factors. In addition, the therapeutic use of HYLO-COMOD and PARIN-POS is accompanied by minimum possible negative side effects and their use can increase the amount of tear film, as well as reduce the severity of eye discomfort.
MODIFICAÇÕES FÍSICO-QUÍMICAS E DAS PROPRIEDADES FUNCIONAIS DE OVOS MARRONS EM FUNÇÃO DO TEMPO E CONDIÇÃO DE ESTOCAGEM
Authors: Marcolino Gherardi Sandra Regina , Porto Vieira Rafael , De Almeida Jhenyfer Caroliny
Published: September 2019

O experimento foi conduzido com o objetivo de avaliar as alterações ocorridas na qualidade, composição química e propriedades funcionais de ovos de poedeiras vermelhas semipesadas da linhagem Hisex Brown com 30 semanas de idade em condição de estocagem ambiente e sob refrigeração por 28 dias. Para determinar a qualidade foi avaliado peso do ovo, gema albúmen e casca, índice de gema, Unidade Haugh (UH), porcentagem de albúmen, gema e casca e pH de albúmen e gema. Para composição química foi avaliada proteína bruta, lipídios totais, sólidos totais, cinzas, e umidade tanto do albúmen quanto da gema. As propriedades funcionais estudadas foram volume de espuma formado e drenado, volume de óleo gasto para formar emulsão, início da desestabilização da emulsão e colorimetria de gema. Os resultados indicaram que os ovos refrigerados mantiveram boa qualidade durante os 28 dias do experimento, enquanto ovos mantidos sob condição ambiente apresentaram qualidade inferior aos sete dias. Em relação aos ovos frescos o índice de gema (IG) de ovos refrigerados sofreu aumento aos sete dias. O tempo de estocagem diminuiu os valores UH sendo observados piores valores para ovos mantidos no ambiente. O peso do ovo foi maior, e o pH do albúmen e gema de ovos refrigerados manteve valores inferiores aos observados em ovos mantidos sob condição ambiente. As médias dos parâmetros físico-químicos variam, a exemplo de proteína bruta da gema, lipídio de albúmen e sólidos totais da gema, que com o decorrer do tempo diminuíram. Em contraste, a umidade da gema, a proteína bruta e sólidos totais da albumina, tendeu a aumentar, enquanto as médias da umidade e cinzas da albumina, cinzas da gema, lipídios da albumina e sólidos totais da gema, se mantiveram mais próximas. Independentemente da temperatura de estocagem, o teor de sólidos totais diminuiu na gema e se elevou no albúmen com o aumento do período de armazenagem. Houve perda de umidade do albúmen em função do período de estocagem sendo maior para ovos mantidos no ambiente. Ocorreu diminuição no volume de espuma formado em função do tempo de estocagem. Independentemente do período de estocagem o volume de líquido drenado e o volume de óleo gasto para formar emulsão foi menor para ovos refrigerados. Ovos mantidos em ambiente aumentam linearmente o volume de líquido drenado em função do tempo de estocagem. O volume de óleo gasto para formar emulsão responde de forma contrária em função do período, com aumento do volume em ovos mantidos no ambiente e diminuição em ovos refrigerados. Ovos refrigerados apresentaram gemas mais escuras e com coloração mais intensa. A estocagem sob refrigeração foi capaz de preservar a qualidade dos ovos por um período de tempo superior, garantindo e melhorando também algumas propriedades funcionais.
FORMULADO DE ALECRIM NO CONTROLE DE ANTRACNOSE E CONSERVAÇÃO EM PÓS-COLHEITA DE BANANA NANICÃO
Authors: Lorenzetti Eloisa , Garcia Souza Dablieny Hellen , Tartaro Juliano , Stangarlin José Renato , Costa Braga Gilberto
Published: September 2019

A banana apresenta elevada suscetibilidade a doenças como as podridões que diminuem o tempo de prateleira do fruto. Uma das formas de controlar as doenças seria a utilização de métodos alternativos como os extratos de plantas medicinais. Assim, o objetivo deste estudo foi verificar a ação de formulados de alecrim (Rosmarinus officinalis L.) pó e líquido no controle de antracnose causada pelo fungo Colletotrichum musae (Berk & Curt.) Von Arx. e na maturação de banana ‘Nanicão’ em pós-colheita. Foram utilizadas as concentrações 0%; 0,25%; 0,5%; 1%; 1,5% e 2% do pó solúvel de extrato de alecrim diluído em água destilada, e as concentrações 0%; 0,5%; 1%; 2%; 4% e 6% do formulado aquoso contendo 21% de resíduo seco de alecrim diluído em água destilada. Foi realizada a mensuração da área de cada fruto e avaliada a severidade e a maturação a partir de porcentagem de área dos frutos, sendo os resultados utilizados para calcular a área abaixo da curva de progresso da doença (AACPD) e a porcentagem de maturação dos frutos. Realizou-se analise de regressão a partir dos dados obtidos e pode-se verificar que para o formulado de alecrim em pó a AACPD reduziu mais de 29% e para a maturação a redução foi de 21,72%. Para o formulado líquido a redução foi de 14,31% para AACPD e cerca de 10% para maturação. Assim, concluiu-se que houve eficiência por parte dos formulados de alecrim no controle da antracnose e no aumento da vida de prateleira da banana ‘Nanicão’.
"Que pedirás, oh senhora, que vos negue o bom Jesus?": culto mariano e epidemia de cólera no interior do Ceará (1855-1862)
Authors: Cadena Paulo Henrique Fontes , Alexandre Jucieldo Ferreira
Published: September 2019

O artigo analisa como – na conjuntura de aproximação de uma epidemia, entre 1855 e 1862 – a região do Cariri, no interior do Ceará, recorreu à Virgem Maria como meio de defesa frente ao cólera. A partir de cartas de sacerdotes e orações publicadas no jornal “O Araripe”, demonstramos como a doença foi representada a partir de um olhar penitencial, pautado na ideia de castigo divino, e como a devoção mariana foi evocada no auxílio dos amedrontados fiéis.
"Atualizando a tradição": sobre casas de saúde no Baixo Amazonas
Authors: Fidelis Juliana Cardoso
Published: September 2019

Neste artigo comentarei sobre a noção de tradição para duas casas de saúde alternativa: Grupo Conquista de Ervas Medicinais e o Grupo Itauajuri Ervas, no Oeste do Pará. Elas foram criadas pela Pastoral da Saúde da Diocese de Santarém por meio do “Projeto pela evangelização”, há 25 anos, e tiveram como objetivo levar tratamentos para a população rural, mas hoje atendem principalmente a urbana. Os tratamentos “tradicionais” que oferecem foram sendo elaborados a partir de levantamentos de práticas locais, mas também no diálogo com concepções médicas, remédios alopáticos, “padrões” sanitários. Nessa combinação, a eficácia dos cuidados é remetida à tradição dos levantamentos comunitários, mas também à atualização de suas práticas.
Faster and Better Nested Dissection Orders for Customizable Contraction Hierarchies
Authors: Gottesbüren Lars , Hamann Michael , Uhl Tim Niklas , Wagner Dorothea
Published: September 2019

Graph partitioning has many applications. We consider the acceleration of shortest path queries in road networks using Customizable Contraction Hierarchies (CCH). It is based on computing a nested dissection order by recursively dividing the road network into parts. Recently, with FlowCutter and Inertial Flow, two flow-based graph bipartitioning algorithms have been proposed for road networks. While FlowCutter achieves high-quality results and thus fast query times, it is rather slow. Inertial Flow is particularly fast due to the use of geographical information while still achieving decent query times. We combine the techniques of both algorithms to achieve more than six times faster preprocessing times than FlowCutter and even faster queries on the Europe road network. We show that, using 16 cores of a shared-memory machine, this preprocessing needs four minutes.
Leguminous Cover Crop Astragalus sinicus Enhances Grain Yields and Nitrogen Use Efficiency through Increased Tillering in an Intensive Double-Cropping Rice System in Southern China
Authors: Nie Jiangwen , Yi Lixia , Xu Heshui , Liu Zhangyong , Zeng Zhaohai , Dijkstra Paul , Koch George W. , Hungate Bruce A. , Zhu Bo
Published: September 2019

Chinese milk vetch (Astragalus sinicus L., vetch), a leguminous winter cover crop, has been widely adopted by farmers in southern China to boost yield of the succeeding rice crop. However, the effects of vetch on rice grain yield and nitrogen (N) use efficiency have not yet been well studied in the intensive double-cropped rice cropping systems. To fill this gap, we conducted a three-year field experiment to evaluate the impacts of the vetch crop on yields and N use efficiency in the subsequent early and late rice seasons. With moderate N input (100 kg N ha−1 for each rice crop), vetch cover significantly increased grain yields by 7.3–13.4% for early rice, by 8.2–10.4% for late rice, and by 8.6–11.5% for total annual rice production when compared with winter fallow. When rice crops received an N input of 200 kg N ha−1, vetch cover increased grain yields by 5.9–18.4% for early rice, by 3.8–10.1% for late rice, and by 6.2–11.3% for annual rice production. Moreover, comparable grain yields (11.9 vs. 12.0 Mg ha−1 for annual rice production) were observed between vetch cover with moderate N and fallow with added N fertilizer. Yield components analysis indicated that the increased tillering number was the main factor for the enhanced grain yields by vetch cover. Vetch cover with moderate and higher N input resulted in higher agronomic N use efficiency and applied N recovery efficiency compared with the fallow treatments. Here, our results showed that vetch as a winter cover crop can be combined with reduced N fertilizer input while maintaining high grain yields, thus gaining a more sustainable rice production system.
Optimization of Nitrogen Rate and Planting Density for Improving the Grain Yield of Different Rice Genotypes in Northeast China
Authors: Zhou Chanchan , Huang Yuancai , Jia Baoyan , Wang Shu , Dou Fugen , Samonte Stanley Omar PB. , Chen Kun , Wang Yan
Published: September 2019

Nitrogen fertilization and planting density are two key factors that can interactively affect the grain yield of rice. Three different types of rice cultivars—inbred Shendao 47, inbred Shendao 505, and hybrid Jingyou 586—were applied to investigate the effects of the nitrogen (N) rate and planting density (D) on the aboveground biomass, harvest index, leaf photosynthetic features, grain yield, and yield components using a split-split-plot design at two sites over two continuous years. The main plots were assigned to four nitrogen fertilizer rates: 0 (N0), 140 (N1), 180 (N2), and 220 (N3) kg ha−1 N; the subplots were assigned to three planting densities: 25 × 104 (D1), 16.7 × 104 (D2), and 12.5 × 104 (D3) hills ha-1, and the sub-subplots were assigned to three rice cultivars. The results showed that the grain yield had a significantly positive correlation with the stomatal conductance (Gs), net photosynthesis rate (Pn), transpiration rate (Tr), chlorophyll content (SPAD value), leaf area index (LAI), panicles per unit area, and spikelets per panicle. The N rate and planting density had significant interaction effects on grain yield, and the maximum values of Shendao 47, Shendao 505, and Jingyou 586 appeared in N3D2, N2D1, and N3D3, respectively. The higher grain yield of midsized panicle Shendao 47 was mostly ascribed to both panicles per unit area and spikelets per panicle. More panicles per unit area and spikelets per panicle primarily contributed to a larger sink capacity of small-sized panicle rice Shendao 505 and large-sized panicle rice Jingyou 586. We found that the treatments N3D2, N2D1, and N3D3 could optimize the contradiction between yield formation factors for Shendao 47, Shendao 505, and Jingyou 586, respectively. Across years and sites, the regression analysis indicated that the combinations of nitrogen fertilization of 195.6 kg ha−1 with a planting density of 22 × 104 hills ha−1, 182.5 kg ha−1 with 25 × 104 hills ha−1, and 220 kg ha−1 with 13.1 × 104 hills ha−1 are recommended for medium-, small-, and large-sized panicle rice cultivars, respectively.
Frequent Klebsiella pneumoniae Urinary Tract Infections in a Patient Treated with Ruxolitinib
Authors: Hanna Ramy M. , Khalid Maham , El-Nour Lama Abd , Selamet Umut
Published: September 2019

Ruxolitinib is a targeted agent that inhibits Janus 2 Kinase and is approved for use in Polycythemia Vera and Primary Myelofibrosis. Its mechanism of action involves inhibition of cellular proliferation via the Janus kinase/signal transducer and activator of transcription proteins pathway. Ruxolitinib has different immune modulating effects that result in functional immunosuppression, leading to an increased susceptibility to certain infections. Klebsiella pneumoniae infections, in particular, were common among the reported pathogens contracted by ruxolitinib users. We report a 75-year-old male patient who had recurrent K. pneumoniae urinary tract infections while on ruxolitinib for Polycythemia Vera. This case is reported to add to the literature describing an increased susceptibility of patients to this often-resistant bacteria and to raise awareness about the immune modulating effects of JAK inhibitors.