bluuebunny/crossref_metadata_2025 huggingface dataset:
The mechanics of a saturated silty loess with a transitional mode
Authors: Xu L. , Coop M. R.
Published: January 2017

Problems of identifying unique normal compression and critical state lines have been found in gap-graded soils and also some silty soils, a mode of behaviour sometimes known as ‘transitional’. Loess is a typical silty soil that covers up to 631 000 km2 in China and is of great significance as a result of the large number of engineering projects under construction. To examine the potential transitional behaviour in loess, an extensive series of carefully controlled oedometer tests and triaxial tests on intact and reconstituted specimens were carried out. Loess specimens with a wide range of initial void ratios were reconstituted using different preparation methods. Intact specimens were taken from two depths, but their natural variabilities were not significant and could be neglected, apart from their difference in the initial void ratios. The results have highlighted the features of transitional behaviour in this loess, not only in reconstituted but also intact states, and in particular that there is an influence of the initial density of this loess on its normal compression and critical state lines. Two factors, m and P, as proposed by earlier research, were used to quantify the degree of transitional behaviour. These indicate that this silty loess has a significant degree of transitional behaviour. The intact specimens possibly have an even more pronounced transitional degree than the reconstituted ones, although this is difficult to confirm because of the limited range of initial specific volumes of the intact specimens. The effects of structure on the mechanics of the intact silty loess have also been identified by comparing the behaviour of the intact and reconstituted soils, and the paper discusses the difficulties of doing this for a soil without a unique intrinsic behaviour.
Fire behaviours of concrete columns with prior seismic damage
Authors: Wu Bo , Xiong Wei , Liu Fentao
Published: January 2017

To investigate the fire behaviours of earthquake-damaged concrete columns, eight reinforced concrete specimens were subjected to cyclic loadings at room temperature. The pre-damaged specimens and one control specimen without pre-damage were then tested in an ISO 834 fire. The experimental parameters of the columns included the intended drift ratio, axial load ratio, volumetric transverse reinforcement ratio and shear span ratio. The test results revealed the following. Compared with the drift ratio, the axial load ratio had a more significantly adverse effect on spalling of the column's concrete cover during the cyclic loading test. When the axial load ratio was 0·5, the influence of drift ratio in the range 0 to 1/65 on the fire endurance of the pre-damaged columns was limited, but fire endurance dropped dramatically for a drift ratio of 1/40. When the axial load ratio was less than 0·25, the fire endurance of the pre-damaged columns was still satisfactory even for an extremely large drift ratio (e.g. 1/26). The fire endurance of the pre-damaged columns increased to some extent with a reduction in shear span ratio.
Wallasea Island Wild Coast Project, UK: circular economy in the built environment
Authors: Cross Martin
Published: January 2017

The Wallasea Island Wild Coast Project in Essex, UK, is transforming 670 ha of farmland back to coastal marshland. A total of 98% of excavated material from the Crossrail project in London has been recycled and reused, with almost half being shipped to Wallasea Island – more than 3 Mt. Up to six ships arrived daily at Wallasea, unloading 8000 t of excavated material. A total of 2400 shiploads of material were delivered, removing the requirement for 150 000 haulage lorry movements from London's roads. The recycled excavation material has been used to raise land levels at Wallasea by ∼1·5 m to create Europe's largest wetland nature reserve. The project includes an innovative flood defence system incorporating new seawalls to protect vulnerable coastal areas from flooding. Partnering with nature conservation charity RSPB was a key part of Crossrail's sustainability policy. The project provides an excellent example of the circular economy in the built environment, where construction materials have been reused in a high-value conservation project providing benefits for both people and wildlife.
Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity
Authors: Hori Yoshihisa , Aoki Nobumasa , Kuwahara Shoji , Hosojima Michihiro , Kaseda Ryohei , Goto Sawako , Iida Tomomichi , De Shankhajit , Kabasawa Hideyuki , Kaneko Reika , Aoki Hiroyuki , Tanabe Yoshinari , Kagamu Hiroshi , Narita Ichiei , Kikuchi Toshiaki , Saito Akihiko
Published: January 2017

Nephrotoxicity induced by antimicrobial or anticancer drugs is a serious clinical problem. Megalin, an endocytic receptor expressed at the apical membranes of proximal tubules, mediates the nephrotoxicity of aminoglycosides and colistin, key antimicrobials for multidrug-resistant organisms. The mechanisms underlying the nephrotoxicity induced by vancomycin, an antimicrobial for methicillin-resistant Staphylococcus aureus, and cisplatin, an important anticancer drug, are unknown, although the nephrotoxicity of these drugs and gentamicin, an aminoglycoside, is suppressed experimentally with cilastatin. In the clinical setting, cilastatin has been used safely to suppress dehydropeptidase-I–mediated renal metabolism of imipenem, a carbapenem antimicrobial, and thereby limit tubular injury. Here, we tested the hypothesis that cilastatin also blocks megalin-mediated uptake of vancomycin, cisplatin, colistin, and aminoglycosides, thereby limiting the nephrotoxicity of these drugs. Quartz crystal microbalance analysis showed that megalin also binds vancomycin and cisplatin and that cilastatin competes with megalin for binding to gentamicin, colistin, vancomycin, and cisplatin. In kidney-specific mosaic megalin knockout mice treated with colistin, vancomycin, or cisplatin, the megalin-replete proximal tubule epithelial cells exhibited signs of injury, whereas the megalin-deficient cells did not. Furthermore, concomitant cilastatin administration suppressed colistin-induced nephrotoxicity in C57BL/6J mice. Notably, cilastatin did not inhibit the antibacterial activity of gentamicin, colistin, or vancomycin in vitro, just as cilastatin did not affect the anticancer activity of cisplatin in previous studies. In conclusion, megalin blockade with cilastatin efficiently suppresses the nephrotoxicity induced by gentamicin, colistin, vancomycin, or cisplatin. Cilastatin may be a promising agent for inhibiting various forms of drug-induced nephrotoxicity mediated via megalin in the clinical setting.
Potassium Sensing by Renal Distal Tubules Requires Kir4.1
Authors: Cuevas Catherina A. , Su Xiao-Tong , Wang Ming-Xiao , Terker Andrew S. , Lin Dao-Hong , McCormick James A. , Yang Chao-Ling , Ellison David H. , Wang Wen-Hui
Published: January 2017

The mammalian distal convoluted tubule (DCT) makes an important contribution to potassium homeostasis by modulating NaCl transport. The thiazide-sensitive Na+/Cl− cotransporter (NCC) is activated by low potassium intake and by hypokalemia. Coupled with suppression of aldosterone secretion, activation of NCC helps to retain potassium by increasing electroneutral NaCl reabsorption, therefore reducing Na+/K+ exchange. Yet the mechanisms by which DCT cells sense plasma potassium concentration and transmit the information to the apical membrane are not clear. Here, we tested the hypothesis that the potassium channel Kir4.1 is the potassium sensor of DCT cells. We generated mice in which Kir4.1 could be deleted in the kidney after the mice are fully developed. Deletion of Kir4.1 in these mice led to moderate salt wasting, low BP, and profound potassium wasting. Basolateral membranes of DCT cells were depolarized, nearly devoid of conductive potassium transport, and unresponsive to plasma potassium concentration. Although renal WNK4 abundance increased after Kir4.1 deletion, NCC abundance and function decreased, suggesting that membrane depolarization uncouples WNK kinases from NCC. Together, these results indicate that Kir4.1 mediates potassium sensing by DCT cells and couples this signal to apical transport processes.
Preparing Data for vContact from Proteins (Cyverse) v3
Authors: Bolduc Benjamin
Published: January 2017

Preparing data for use in vContact by usingVirSorted Ocean Sampling Day (2014) contigs, using tools available inCyverse. This protocol creates a BLAST DB, BLASTs sequences, and creates a gene-to-contig mapping file. Results from this protocol are suitable for vContact-PCs.
Amate Paper Culture in San Pablito, Pahuatlán, Puebla, Mexico
Authors: Jiménez Velázquez Mercedes A. , Castillo María Janet Fuentes , Saldaña Tomas Martínez
Published: January 2017

Amate paper is the results of artisan family labor in San Pablito, in the Otomi indigenous community, Pahuatlán, Mexico. It is a product of pre-Columbian origin, and its production continues today through the transmission of their culture in local families. Its manufacture requires bark fibers from jonote trees. The promotion of tourism transformed artisanal crafts into merchandise and increased demand. As well, it promoted problems with environmental contamination and a high dependence on business intermediaries. In analyzing such production, indicators of sustainability were considered to be social, economic, and environmental. Results show that the primary income generating activity in the community is making amate paper, which preserves continuity in the transmission of ancestral artisanal knowledge. Yet, sustainability of production is low due to excessive use of natural resources, the use of chemicals in the production process, and poor community organization.
Physical, Chemical, and Microbiological Characteristics of Ronto During Storage
Authors: Khairina Rita , Cahyanto Muhammad Nur , Utami Tyas , Rahardjo Sri
Published: January 2017

The purpose of this study was to determine the physical, chemical, and microbiological changes of ronto during storage at room and cold temperatures. Ronto was prepared by mixing fresh shrimp, salt, and rice with a ratio of 7 : 1 : 2 and fermented in a closed container for 14 days. Ronto produced was stored at room and cold (5o C) temperatures. Samples were withdrawn every 4 weeks and analyzed for its physical, chemical, and microbiological characteristics. The characteristic changes of ronto stored at low temperature were generally slower than those at room temperature. The changes in colour, viscosity, acidity, total volatile bases, and microbial counts were lower in ronto kept at 5o C compared to those in ronto kept at room temperature. The colour of ronto stored at low temperature remained red after 20 weeks, whereas the colour of ronto kept at room temperature turned brownish after 20 weeks.
Agency Theory Applied to the Italian Revenue Agency: Accountability Policies as Bonding Costs
Authors: Castellini Monia , Riso Vincenzo
Published: January 2017

This paper aims at studying the consequences of the Agency Theory application at the case of the Italian Revenue Agency (afterwards IRA). The major countries in the world entrust the tax administration to the Agencies that make use of various strategies to manage tax revenue and to contrast tax avoidance. In the last years the Organisation for Economic Co-operation and Development (afterwards OECD) has invited many States to increase the tax compliance between Public Tax Administration and Taxpayers and to improve the relationship with these. There are more scientific contributions about the themes like the Agency Theory, the Stakeholder’s Theory and other more on Governance and Accountability policies: many of these will be discussed in this work. In the light of these observations the research question is: given that IRA plays a central role in the tax administration, what happen if we apply the Agency Theory on this? What are the Agency costs in this case? To answer to these question we have studied the Law provisions in the Italian tax field and the “way to do” of the IRA. So, this work not is only a theoretical analysis of the scientific literature but it move to analyse the implications of these on the real case. The conclusions achieved in this paper are based on the analysis of the Italian case that only partially brings a solution to this question. However it represent the first point for us to beginning a future comparison between the evidences in the international context.
Estudio Del Liderazgo Estudiantil Desde Las Motivaciones Para Su Elección. El Caso De La Universidad De Santo Tomás De Bucaramanga (Colombia)
Authors: Gómez Miguel López , Rodríguez-García Antonio-Manuel , Montoro Miriam Ágreda
Published: January 2017

This paper shows an investigation developed at the University of Santo Tomás (Bucaramanga) about the qualities that students consider important to practice the student leadership. For that reason, an ad hoc questionnaire with a reliability index of 0,814 has been designed. The sample consisted of 38 students (55% male and 45% female) from different degrees. The results show values such as charisma, commitment, consistency, fidelity, honesty, loyalty, frankness, sincerity and firmness of the person as the most important qualities that the student must have to be chosen as a representative of students.
The Role of Corporate Governance Failure in the Banking Sector
Authors: Dibra Rezart
Published: January 2017

Corporate governance is the organizational arrangement by which a company represents and serves the interests of its investors. It encompasses anything from a company’s boards to executive compensation schemes to bankruptcy laws. Generally, the definitions of corporate governance which was found in the literature tend to share certain characteristics. One of this characteristic is the notion of accountability. Corporate governance is the process of supervision and control which intends to ensure that the company’s management acts in accordance with the interests of shareholders (Parkinson, 1994). Corporate governance, the internal policies and leadership that guide the actions of corporations, played a major part in the recent global financial crisis. While much blame has been targeted at compensation arrangements that rewarded extreme risk-taking but did not punish failure, the performance of large, supposedly, sophisticated institutional investors in this crisis have not been examined. Corporate governance has come to the forefront of academic research due to the vital role it plays in the overall health of economic systems. Corporate governance was long ignored as a matter of potential importance for the development of a nation’s economy. This paper, however, expresses some cases in the field of corporate governance, regarding the failure of corporate governance. Institutional investors failed to effectively monitor such volatile investments, ignoring relatively well-established corporate governance principles and best practices. Corporate Governance Failures offers nuanced and realistic proposals to mitigate future financial pitfalls.
A Survey of e-Commerce Recommender Systems
Authors: Karimova Farida
Published: January 2017

Due to their powerful personalization and efficiency features, recommendation systems are being used extensively in many online environments. Recommender systems provide great opportunities to businesses, therefore research on developing new recommender system techniques and methods have been receiving increasing attention. This paper reviews recent developments in recommender systems in the domain of ecommerce. The main purpose of the paper is to summarize and compare the latest improvements of e-commerce recommender systems from the perspective of e-vendors. By examining the recent publications in the field, our research provides thorough analysis of current advancements and attempts to identify the existing issues in recommender systems. Final outcomes give practitioners and researchers the necessary insights and directions on recommender systems.
Caracterización Ecológica De Bofedales, Hábitat De Vicuñas Aplicando Metodologías De Teledeteccion Y Sig Estudio De Caso: Reserva De Producción De Fauna Chimborazo
Authors: Díaz Moyota Paulina Beatriz , Verdugo Bernal Catalina Margarita , Guadalupe Carla Sofía Arguello , Santillán Carlos Arturo Jara , Barahona Byron Ernesto Vaca , Villavicencio Andrés Alejandro Yépez , McLaren Brian E.
Published: January 2017

This article presents a methodology based on classification of images from Landsat 7 ETM + to classify Andean wetlands known as ¨Bofedal¨ (wetland) located in the Fauna Production Reserve Chimborazo. Five of the seven in-situ geo-referenced bofedales belong to this category and two belong to the altiplano. These georeferenced reservoirs are the principal habitat of the vicuñas that are located within the RPFCH in the jurisdictions of the province of Tungurahua: Río Blanco, ¨Mocha¨ Valley area, 472.26 ha, 4400 m.; Chimborazo Province: Bofedal Quebrada Toni, Urbina area, 16.74 ha, 4301 m, bofedal El Refugio (Hermanos Carrel) at the Nevado Chimborazo, 1.44 ha, 4800msnm, and Curi bofedal Pogyo, Chorrera Mirador, 0.34 ha., 4523 m. and in the Bolivar Province: the wetlands Chag Pogyo, Pulinguí San Pablo, 19.36 ha, 4064 meters above sea level. Bofedal Sinche1, the sector ¨antennas¨, 8.53 ha. 4167 m., And Sinche2, ¨Puente Ayora¨ area, 9.39 ha., 3981 meters, the latter being Chag Pogyo highland bofedales. The seven bofedales represent 0.93% (527.87 ha) of the total area of the RPFCH (56653, 27 ha.). Two images of the satellite Landsat 7 ETM +, from the years 2001 - EarthSat, 2004 - USGS and an orthophoto 2013-2014 - GIS land were used. Georeferenced and rectified to capture the spatial and temporal variability of these ecosystems and define the characterization of bofedales in the reserve. For each image two classification methods were used, the supervised classification being the most efficient when representing the four representative classes in the RPFCH: snow, rock, pajonal and bofedal. Since this classification is oriented to objects that takes into account aspects such as shape and texture and not just the spectral information of each pixel. Allowing to obtain information on the characteristics and spatial distribution of the bofedales which was verified and validated later in the field. This process allows the generation of digital cartography with the identification, delimited and distributed bofedales along the RPFCH, representing a total of approximately 1483.94 ha in the RPFCH. In addition, the Normalized Difference Vegetation Index (NDVI) was applied, which made it possible to differentiate water bodies from other coverages, as well as specifically to know the extent of the reservoirs present in the Reserve, in order to better infer Distribution of vicuñas.
Diversité Et Structure Floristiques Sous Des Peuplements d’Acacias Australiens En Zone Forestière De La Côte d’Ivoire
Authors: Richard Kouadio Kouassi , Adama Bakayoko , Anatole N’guessan Kanga , Djezou Konan
Published: January 2017

Since thirty years, four Australian Acacias species are introduced and studied in Anguédédou Research station. The station research is located in evergreen forest in the south of Côte d'Ivoire. The objective of the introduction of these species, is to rehabilitate degraded grounds and fallow after growing. The study aims at appreciating the impact of Acacia species on floristic diversity and the regeneration of forest species. For collecting data, we use quadrat method (35 x 50 m and 6 x 6 m).This method permitted the inventory of 212 species on 1.05 ha. Among these species, 1.89 % are Ivorian endemic species and 11.32 % are endemic of West African flora. The flora under the different species of Acacia are relatively diversified and dense. The majority of plant inventoried under Acacia species have small diameters. The highest specific richness average per plots (36 m2) were noted in the 11 years old parcels of Acacia mangium (26.20±2.34) and 27 years old parcels of Acacia auriculaeformis (25.40±2.34) and Acacia crassicarpa (30.60±2.34). The mean values of diameters (dbh ≥ 2.5 cm) fluctuate from 2.94±0.56 cm for the 8 years old stands of Acacia mangium to 8.09±0.56 cm for the 27 years old settlements of Acacia crassicarpa. The results show that leguminous trees can be used for recolonization of the deforested areas in order to rebuild quickly their plant biodiversity.
Caracterización Ecológica Cuantitativa De La Vegetación En Sitios De La Costa Central Del Golfo En El Desierto Sonorense
Authors: Galván Carlos Hugo Alcalá , Gaytán José Enrique Maytorena , Guardado Ramón Héctor Barraza , Rueda-Puente Edgar Omar
Published: January 2017

The Central Gulf Coast, subdivision of the Sonoran Desert, requires urgent actions to ecological restoration and development of sustainable alternatives to promote the generation of economic benefits in a manner consistent with the conservation of natural resources. Four sites were selected in the coastal region of the municipality of Hermosillo between 28°42'04" and 28°52'24" North and 111°45'39" and 111°56'48" West. Sites are representative of the various plant associations with variants in soil structure, topography and intensities of use. General plant diversity, plant density, height and canopy cover from shrub/tree plants, and basal cover from herbaceous plants were evaluated at each site. Species richness indices, equity and diversity among plant communities were compared. Major plant associations were identified as 1) Sarcocaulescent scrub, 2) Halophytes Communities, 3) Arbo-crasicaulescent scrub, and 4) Arbo-suffrutescent scrub. Sixty five plant species in 26 families were identified. Families with higher number of species were Cactaceae (12), Euphorbiaceae (7), Fabaceae (7) and Malvaceae (5). Species richness and diversity indices indicated differences between sites. Values of relative importance are identified among plant associations for subsequent analysis of productive and ecological trends as well as for the assessment of wildlife diversity and population parameters associated to each condition of the vegetation. This work is aimed to generate integral models for identifying feasibility and setting priorities for ecological restoration practices in the Sonoran Desert.
Does Domestic Work Affect the Academic Performance of Girls in Primary School in Côte d’Ivoire? Empirical Evidence from Probit Model
Authors: Abou Pokou Edouard
Published: January 2017

The objective of this paper is to highlight the effects of domestic work of girls on their school results in Cȏte d’Ivoire. From a probit model, the analysis indicates that domestic work favours, meaningfully, the fact about repeating a school year for the girl child. Besides, the availability of basic services in schools significantly reduces failure of girls in schools in rural areas. Thus, policy makers must equip schools with canteens, toilets for girls, and they should also provide the necessary facilities for drinking water points.
Enjeux Socio-Économiques Et Contraintes Liés À L’hévéaculture En Pays ͻdjukru Dans La Région De Dabou (Côte d’Ivoire)
Authors: Simeon Akmel Meless
Published: January 2017

Rubber production is an activity that grows at the global scale. In Ivory Coast, it has a prominent place, as the country is mainly based on agriculture and the people are more and more interested in that activity. The ͻdjukru people (Dabou region) is also involved in the production of rubber (white gold). Being both qualitative and ethnographic, this study on rubber presents the results obtained from of a field investigation. It concerns the economic value of rubber production, which provides populations with a lot of money. It has also a socio-cultural value, to the extent that income from the trading of latex is used for to meet the people’s daily needs (food, housing, education, clothing, initiation rites). Accordingly, rubber production plays a double role in the region, as to its two principal functions: the first is obvious (economic and social) and the second is latent (cultural).The populations’ interest in rubber production cause many workplace accidents (injuries), diseases (joint pain, respiratory diseases), the significant reducing in arable land, all of which qualify this activity as a risky wealth.
Utilization of Social Networks among Saudi EFL Learners: Trends and Uses
Authors: Alkhatnai Mubarak
Published: January 2017

The aim of this paper is to investigate the use of social networking sites among learners of English as a foreign language (EFL) in Saudi institutions of higher education. The actual study was conducted at the King Saud University (KSU). Reports on the extent to which the students are familiar with social media and the manner in which they utilize the technology were obtained. The research also examines the perception of students regarding the use social networking sites in their learning. The percentage of students using the social media and their frequency of visiting the sites also form part of the discussion of this paper. This is in an attempt to draw a clear picture of how the utilization of this new technology is emerging in Saudi higher education. The findings are discussed in light of students’ actual use and their perceived beliefs about the use of such technologies in their learning and social life.
Legal Aspects of Labor Migration and Trafficking in Human Beings
Authors: Kukhianidze Lasha
Published: January 2017

The paper deals with the legal aspects of the problems of labor migration and human trafficking, its causes and factors, the trafficking scale. When considering economic causes we refer to the demand for low-cost labor, as a characteristic factor of globalization, which in turn, greatly effects the international labor migration and is one of the root causes of human trafficking. In the analysis of the social causes the focus is mainly made on the low-pay employment or lack of working conditions.
El docente ante el oficio de investigar en el aula
Authors: Bolaños Motta José Ignacio
Published: January 2017

El presente escrito está inspirado en la canción titulada La fábula de los tres hermanos, del cantautor cubano Silvio Rodríguez Domínguez. Se espera que a través de estos tres apartes de la letra de esta canción, consecuentemente seleccionados, se genere una reflexión en torno a la actividad de generar proyectos de investigación en la escuela secundaria, o como se suele denominar actualmente investigación en el aula, al respecto se abordan las complicaciones, tópicos y demás problemáticas que eventualmente se pueden presentar en la multiplicidad de compromisos cotidianos ante los cuales se ve enfrentado el docente, al momento de desarrollar un proyecto de investigación en una comunidad educativa desde la metodología de la etnografía, hoy usada en los modelos de investigación en educación y pedagogía. Este documento tiene por objetivo generar una reflexión en torno a la mirada del maestro de escuela secundaria, ante el acto de investigar su contexto escolar de trabajo, y el papel de las universidades, en lo que concierne a la formación de licenciados con competencias en investigación educativa.
Reflexiones éticas sobre gestión de la diversidad en educación superior inclusiva
Authors: Acevedo Zapata Sandra
Published: January 2017

El artículo presenta reflexiones con el propósito principal de visibilizar la necesidad de apropiar la cultura organizacional desde la ética, a través de la gestión de la diversidad en las instituciones de educación superior. Para esto se ubican algunos elementos constitutivos de la ética y de las prácticas éticas con sus dimensiones, en relación con la gestión de la diversidad desde la perspectiva planteada por Ventosa (2012), para acercar a las instituciones a apropiar la educación superior inclusiva con sus características como lo aborda Blanco (2008). Con respecto a lo metodológico se desarrolló una investigación exploratoria con matrices de doble entrada donde se categorizó y clasificó la información verbal y documental fruto de entrevistas, registros anecdóticos y archivos documentales, sobre los cuales se desarrolla el análisis y las reflexiones finales que se recogen en este artículo, allí se resalta la necesidad de trasformar las prácticas cotidianas sobre la base de las dimensiones y categorías de la gestión de la diversidad.
La confianza de los adolescentes escolarizados en las redes sociales virtuales
Authors: Soler Fonseca Angela Marcela
Published: January 2017

Este artículo hace aproximación a la realidad de la confianza que se da en las relaciones generadas desde las redes sociales y aplicaciones virtuales más usadas por los adolescentes escolarizados, en los instituciones educativas de Tunja. El fortalecimiento de la confianza cumple una función dinamizadora de formación social y ciudadana en las relaciones escolares, y marcan un derrotero que da respuesta a las complejidades de la convivencia escolar, inclusive a aquellas de la virtualidad que trascienden las instituciones educativas. El estudio de caso múltiple se llevó a cabo en dos instituciones educativas: una privada católica y otra pública laica; ambas con horizonte institucional basado en la formación humana y caracterizadas por la convergencia cultural de sus actores. La investigación mixta, pudo contrastar las voces de los usuarios de estos medios, con los datos cuantitativos y cualitativos obtenidos. Se concluye que los adolescentes escolarizados confían medianamente en las relaciones generadas en las redes sociales virtuales; es decir, han provocado un pensamiento crítico de las mismas, que promueve la prevención y el autocuidado en la Red. Así mismo, la red social virtual más usada es Facebook y la aplicación móvil virtual con mayor aceptación es WhatsApp, las cuales son manejadas en y para la socialización escolar.
Las preposiciones en y a en sintagmas con nombre de objeto. Una descripción desde el enfoque cognitivo: el caso de 'volante' y 'timón'
Authors: Hernández Patricia C.
Published: January 2017

El presente artículo aborda la aparente alternancia de las preposiciones en y a seguidas de los lexemas volante y timón en escenas espaciales que localizan una figura con respecto a una base u objeto de referencia. Postulamos que, si bien estos sintagmas preposicionales comparten una amplia gama de contextos, no evocan necesariamente la misma escena. Nuestro estudio propone una caracterización de su comportamiento semántico-pragmático desde una perspectiva cognitiva: sostenemos que (i) la construcción del sentido es un proceso holístico y (ii) las palabras son modos de acceso a marcos de interacción socialmente compartidos. Nuestra aproximación teórica se basa substancialmente en los conceptos de rol télico, marcos de interacción, zonas activas, conexiones metonímicas y metafóricas. Un estudio cualitativo de 671 enunciados arroja luz sobre las particularidades de cada expresión: los sintagmas preposicionales en el volante / timón pueden localizar tanto figuras animadas como inanimadas mientras que los SP al volante / timón requieren figuras animadas que mantengan una interacción pertinente con el objeto de referencia. Además, puede observarse que frecuentemente los sintagmas con el lexema timón dan lugar a proyecciones metafóricas.
Ab initio study of graphene interaction with O2, O and O-
Authors: Vasic Anicijevic Dragana , Perovic Ivana , Maslovara Sladjana , Brkovic Snezana , Zugic Dragana , Lausevic Zoran , Marceta Kaninski Milica
Published: January 2017

A systematic ab initio (DFT-GGA) study of adsorption of various oxygen species on graphene has been performed in order to find out general trends and provide a good starting point to analyze the oxidation of more complex carbon materials. Particular attention was paid to finding an appropriate supercell model. According to our findings, atomic O is characterized by stable adsorption on graphene and very strong adsorption on defective graphene. On the other hand, O2 does not adsorb on graphene and is allowed to diffuse freely to the defect, where it is expected to dissociate into two strongly adsorbed O atoms. The obtained results were compared with available theoretical data in the literature and good agreement was achieved.

 
Minerals from Macedonia. XXX. Complementary use of vibrational spectroscopy and X-ray powder diffraction for spectra-structural study of some cyclo-, phyllo- and tectosilicate minerals. A review
Authors: Jovanovski Gligor , Makreski Petre
Published: January 2017

A review of the results of the complementary use of vibrational spectroscopy (infrared and Raman) and X-ray powder diffraction in the process of identification and spectra–structure correlation of some cyclo-, phyllo- and tectosilicate minerals originating from the Republic of Macedonia             is presented. The following minerals are studied: schorl, Na(Fe2+,Mg)3Al6(BO3)3Si6O18(OH)4;               beryl, (Be,Mg)3Al2Si6O18; chrysotile, Mg3Si2O5(OH)4; antigorite, (Mg,Fe2+)3Si2O5(OH)4; talc, (Mg,Fe2+)3Si4O10(OH)2; clinochlore, (Mg,Fe2+)5Si3(Al,Cr)2O10(OH)8; cymrite, BaAl2Si2O8×H2O; mont­morillonite, (K,Ca)0.3(Al,Mg)2Si4O10(OH)2×nH2O; muscovite, KAl2(Si3Al)O10(OH,F)2; phlogopite, KMg3(Si3Al)O10(OH,F)2; biotite, K(Mg,Fe2+)3AlSi3O10(OH,F)2; sheridanite, (Mg,Al)6(Si,Al)4O10(OH)8; albite, NaAlSi3O8; microcline, KAlSi3O8; sanidine, (K,Na)(Si,Al)4O8 and stilbite, Na3Ca3Al8Si28O72×30H2O.
Theoretical model of infrared spectra of hydrogen bonds in molecular crystals of 2-thiopheneacetic acid: Fermi resonance and Davdov coupling effects.
Authors: Issaoui Noureddine , Abdelmoulahi Hafedh , T. Flakus Henryk , Ghalla Houcine , Oujia Brahim
Published: January 2017

A quantum theoretical approach, within the adiabatic approximation and taking into account a strong non-adiabatic correction via the resonant exchange between the fast mode excited states of the two moieties of the dimer. The intrinsic anharmonicity of the low-frequency mode through a Morse potential, direct and indirect damping, and a selection rule breaking mechanism for forbidden transitions, is applied to reproduce the υX-H IR line shape of cyclic dimers of moderately H-bonded species in the crystalline phase. The results are used to gain an insight into the experimental spectral line shapes obtained by the transmission method. This approach fits satisfactorily the experimental line shape of 2-thiopheneacetic acid and predicts their evolution with isotopic substitution. Numerical calculations show that mixing of all these effects allows one to reproduce the main features of the experimental IR line shapes. 
Characterization of Co(II)-PAMAM dendrimer complexes with polypropylene oxide core by using UV-VIS spectroscopy
Authors: Ertürk Ali Serol , Gürbüz Mustafa Ulvi , Tülü Metin , Bozdoğan Abdürrezzak Emin
Published: January 2017

The aim of this study was to characterize poly(amidoamine) (PAMAM) dendrimer complexes of Co(II) ions by using UV-Vis spectroscopy. For this aim, a generation-4 polypropylene oxide (Jeffamine® T-403) cored and amine-terminated PAMAM dendrimer (P4) was used as a model complexation agent. Optimum complexation condition for P4 was determined by potentiometric and spectroscopic titration studies. Extent of protonation (EOP) of the amino groups of P4 was determined from the potentiometric titration data and validated with spectroscopic titration data. The results indicated that pH 8 was the optimum dendrimer aqueous solution media, where the available number of tertiary amines present in P4 was the highest for possible metal complexation. At the optimized conditions, UV-Vis characterization of the Co(II)-P4 complexes was performed and 585–635 nm d-d transition bands were observed as the characteristic complexation bands of the tertiary amine groups of P4 with Co(II) ions. Obtained Co(II)-P4 complexes might be considered for the development of magnetic resonance image (MRI) improvers or MRI contrast agents.
Synthesis, physicochemical characterization and antibacterial activity of novel (benzoylamino)methyl derivatives of quinolones
Authors: Breznica-Selmani Pranvera , Mladenovska Kristina , Dräger Gerald , Mikhova Bozhana , Panovski Nikola , Kaftandzieva Ana , Kavrakovski Zoran , Hoxha Ahmet , Sheqerxhiu Nardi , Jurhar Pavlova Maja , Popovski Emil
Published: January 2017

Herein we report the synthesis of different derivatives of (fluoro)quinolones norfloxacin, ciprofloxacin and pipemidic acid, by incorporating (benzoylamino)methyl on the free nitrogen of the pyperazinyl moiety. The compounds were structurally characterized by 1D and 2D NMR, FTIR and high-resolution mass spectroscopy. In addition, their physicochemical properties were a matter of interest to be correlated with their structure and antimicrobial activity in vitro. Their antimicrobial activities were screened against Gram-positive, Gram-negative bacteria and C. albicans. Higher distribution coefficients and consequently lower water solubility were determined for all synthesized compounds than the ones of the corresponding leading compounds. Inconsequential correlations between the lipophilicity of the compounds and MIC were observed, suggesting that passive diffusion is not the only mechanism for their penetration into bacterial cells. Further studies are needed to determine how substitutions in the (fluoro)quinolone moiety affect the primary target(s), substrate behavior in respect to bacterial transporters and overall bioavailability.
Cuidados paliativos en la enfermedad de Huntington: perspectivas desde la atención primaria de salud.
Authors: Espinoza-Suárez Nataly R. , Palacios-García Jimmy , Morante-Osores María del Rocío
Published: January 2017

La enfermedad de Huntington (EH) es una enfermedad neurodegenerativa devastadora, hereditaria, caracterizada por  síntomas progresivos motores, cognitivos y psiquiátricos, los cuales aparecen mayormente durante la vida adulta. Su curso clínico produce   consecuencias físicas, emocionales, cognitivas, sociales y económicas graves en el paciente y cuidadores. Su prevalencia a nivel mundial se estima en 7-10 por 100000 habitantes pero, en la zona del Valle de Cañete en nuestro país, se estableció en más de 40 por 100,000. Actualmente no existe cura para la EH; sin embargo, se dan opciones terapéuticas para el alivio de  síntomas con el fin de mejorar la calidad de vida del paciente. Es en este rubro donde radica la importancia de los Cuidados Paliativos,  definidos por la Organización Mundial de la Salud como un enfoque de atención que, mediante medidas de prevención y alivio del sufrimiento, asiste eficazmente a las personas enfermas y a sus familiares en el afronte de problemas asociados con enfermedades mortales. A pesar del impacto que genera esta patología en nuestra población, nuestro país carece de recursos suficientes para el tratamiento integral de los pacientes. Mejorar la atención al final de la vida es un reto moderno que requiere incrementar la formación de los profesionales de la salud y la comunidad, mayor financiación para la atención y desarrollo de políticas pertinentes.
Arteritis de Takayasu : Etiología inhabitual de infarto cerebral. Reporte de un caso
Authors: Meza-Capcha Kelly J. , Barrientos-Imán Danny M. , Valencia-Chávez Ana M. , Ramírez- Quiñones Jorge A. , Abanto-Argomedo Carlos
Published: January 2017

La arteritis de Takayasu (AT) es una vasculitis crónica de grandes vasos que afecta a la aorta y a sus principales ramas. La presentación clínica inicial generalmente se manifiesta con síntomas constitucionales inespecíficos, pero de forma ocasional puede debutar con isquemia de un órgano determinado. Presentamos el caso de una mujer de 31 años de edad sin ascendencia japonesa, sin factores de riesgo vasculares, que presentó de forma súbita déficit motor en hemicuerpo derecho y alteración del lenguaje. Al examen físico se encontró ausencia de pulso en una arteria distal y una diferencia en la presión arterial en los miembros superiores. La angiografía por sustracción digital mostró oclusión de la arteria subclavia y carótida común izquierda, así como estenosis severa de la arteria subclavia derecha en su parte media. Se diagnosticó AT de acuerdo a los criterios diagnósticos del Colegio Americano de Reumatólogos de 1990 y los Criterios modificados de Ishikawa. La paciente recibió tratamiento médico y de la rehabilitación con buena respuesta. La AT debe considerarse como posibilidad etiológica en todos los pacientes jóvenes que presenten un infarto cerebral. Su diagnóstico precoz es crucial, ya que esta patología es sensible al tratamiento médico y se asocia con buenos resultados clínicos.
Acerca de la “Doble contabilidad” de Bleuler como término psicopatológico.
Authors: Strobbe-Barbat Mariella , Cruzado Lizardo
Published: January 2017

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SYNTHESIS OF METAL-ORGANIC (COMPLEXES) COMPOUNDS COPPER(II)-IMIDAZOLE FOR ANTIVIRAL HIV CANDIDATE
Authors: Sucipto Teguh Hari , Martak Fahimah
Published: January 2017

The human immunodeficiency virus (HIV) is viruses known as rotaviruses. Potential target for therapeutic is reverse transcriptase (RT), possesses an RNA-dependent DNA polymerase, DNA-dependent DNA polymerase and ribonuclease H fuctions. Imidazoles have high anti-HIV inhibitory activity, some derivates of imidazole reported drugs. 8-chloro-2,3-dihydroimidazole[1,2-b][1,4,2]benzodithiazine-5,5-dioxides and 9-chloro-2,3,4-trihydropyri-mido[1,2-b][1,4,2]benzodithi-azine-6,6-dioxides. This compounds succesfully identified anti-HIV activity. Copper is a bio-essential element and copper complexes have been extensively utilized in metal mediated DNA cleavage for the generation of activated oxygen species. It has been reported that teraaza macrocyclic copper coordination compounds have anti-HIV activities. Studies have shown that these macrocyclic complexes can react with DNA in different binding fashions and exhibit effective nuclease activities. Complex compounds are compounds in which there is an atom that acts as the central atom and trotter group of molecules that can be either neutral or charged ions. Application a metal-organic (complex) compounds, especially copper metal and derivates of imidazole. So, in this study can explore new anti-HIV candidate.
Production and Characterization of Immunoglobuline Yolk as anti antigen membrane Toxoplasma gondii
Authors: Puspitasari Heni , Praptiwi Yuliana , Suwanti Lucia
Published: January 2017

Toxoplasma gondii is an obligate parasite intracellular which can infected human and other mammalian. Immunoglobulin Y technology  offers several  advantages better than antibody production in mammals. This research was aimed to get immunoglobulin Y from egg yolk, to prove that antibody against membrane T. gondii antigen can produced from immunoglobulin Y and to know the characterization of  immunoglobuline Y according to  molecular weight by SDS PAGE and reactivation of  antibody antigen  by Western Blott. This research devided  from many step : passase tachyzoites T. gondii into mice by peritoneal infection, cultivated  the tachyzoite from intraperitoneal fluid, preparation of  membrane antigen tachyzoite T. gondii, then  immunization laying hens with membrane antigen, extraction and purification immunoglobuline Y from egg yolk and then protein analyzed by SDS PAGE and Western Blott.  The result of this resarch showed that immunoglobulin Y from egg yolk can  produced antibody against protein membrane T. gondii. The result of analyzed profile protein immunoglobuline  Y according SDS PAGE  has molecular weight 179,8 kDa. Analyzed from Western Blott showed that immunoglobulin Y can recognize antigen epitope of  T. gondii on molecular weight 35,7 kDa and 78,8 kDa.
Synergistic Effect of Coadministration of Haemophilus influenzae and Neisseria meningitidis Vaccines on Immune Responses to Meningitis in Mouse Model
Authors: Ali Randa H. , Abdeltawab Nourtan F. , Hady Osama A. , Amin Magdy A.
Published: January 2017

Meningitis is a severe disease associated with death in children under five with highest rates of infections under age of one. Vaccines for Neisseria meningitides and Haemophilus influenza are used to prevent the main causative agents of meningitis. Administration of H. influenzae type b (Hib) vaccine is recommended at 2, 4 and 6 months with a booster dose at 18 months. N. meningitidis has two commercially available vaccines, the pure polysaccharide is recommended at 24 months meanwhile the protein-conjugated vaccines at 12 months. We sought in this study to examine if coadministering the vaccines for the two main meningitis causing bacteria might be synergistic as a preliminary step towards the possibility of shuffling immunization schedule. So, we coadministered Hib vaccine with commercially available vaccines either quadrate (ACWY) polysaccharide meningococcal (Men) or conjugated meningococcal (Nim) vaccines in Balb/C mice (n = 6/group) and compared to each vaccine administered separately and controls. Thirty-five days post immunization, we measured specific antibodies titers. Hib vaccine increased Men antibody titers significantly for serotypes Y and W. When Hib vaccine was coadministrated with Nim, antibody titer for Y, W and A significantly increased. For serotype C, there was no significant difference in antibody titers among immunized groups. As for effect of meningococcal vaccines on Hib, Men significantly increased Hib antibody titers while Nim had no effect. Collectively, our data suggested that coadministration of Hib and Men or Nim vaccines was safe and had synergistic effect on immune responses elicited to both vaccines. Further studies are needed before immunization schedule modifications. Such immunization schedule recommendation should provide better protection against this life-threatening disease in young children.
The Effect of Existing Knowledge Assets on Inbound/Outbound Disruptive Innovation
Authors: Lin Chun-pei , Yu Chuan-peng , Wu Tung-Ju , Wu Yen-Chun
Published: January 2017

Innovation is an essential key factor in the technology development history. Past research on innovation focused more on the innovation behavior of technology, but seldom described knowledge assets which also influence innovation behavior greatly. The effect of knowledge assets attribute and result on disruptive innovation is therefore regarded as the research topic in this study, where disruptive innovation is divided into outbound and inbound to combine combination-embeddednessandmajor business specificityof knowledge assets as the research model. Manufacturing enterprises in China are proceeded the questionnaire survey, and 173 valid copies are collected. The empirical analysis shows that combination-embeddedness of knowledge assets presents significantly positive effects on major business specificity and outbound innovationof an enterprise but reveals remarkably negative effects on inbound innovation. Enterprises are suggested to constantly accumulate knowledge assets with low major business specificity before disruptive innovation in order to reduce ineffective inbound innovation.
Evaluation of Additive Manufacturing Processes in Fabrication of Personalized Robot
Authors: Wang Shushu ,   The Harold and Inge Marcus Department of Industrial and Manufacturing Engineering,, Badarinath Rakshith , Lehtihet El-Amine , Prabhu Vittaldas
Published: January 2017

Customer participation in the design stage of creating personalized products is increasing. Additive manufacturing (AM) has become a popular enabler of personalization. In this study, we evaluate the fabrication of an open-source robot arm in terms of cost, build time, dimensional and locational accuracy, end-effector accuracy, and mechanical properties. The mechanical components of the table-top robot were fabricated using two different AM processes of fused deposition modeling (FDM) and material jetting (polymer jetting or PolyJet). A reduction of infill density by 50% in the FDM process slightly decreased the building time, material cost, and tensile strength, but induced a 95% reduction in yield strength. A simulation of the mechanical assembly using the CAD models for the robot and the expected tolerances of the components estimated the end-effector positioning accuracy as 0.01–0.22 mm. The 3D printed robot arm was redesigned and fabricated using the best evaluated process in this study.