bluuebunny/crossref_metadata_2025 huggingface dataset:
Potencial neklassicheskih kletochnyh kul'tur dlya proizvodstva bioterapevticheskih belkov
Authors: Добронос М. А. , Осипова З. М. , Мышкина Н. М.
Published: June 2024

Proizvodstvo bioterapevticheskih preparatov, v chastnosti, rekombinantnyh belkov v kletkah mlekopitayushchih mozhet byt' zatrudneno iz-za ogranichenij ispol'zuemyh kul'tur v svyazi s metabolicheskoj nagruzkoj. Al'ternativnym podhodom dlya resheniya takih zadach yavlyaetsya narabotka belkov v kletkah drugih zhivotnyh (naprimer, kul'tury kletok nasekomyh Sf9, S2 i High Five, kul'tury kletok chervej vidov Caenorhabditis elegans i Schistosoma mansoni) ili ortogonal'nyh kletochnyh sistemah, v tom chisle rastitel'nyh. S nashej tochki zreniya, primenenie neklassicheskih kletochnyh kul'tur mozhet stat' perspektivnym napravleniem dlya polucheniya bolee dostupnyh i effektivnyh bioterapevticheskih preparatov.
La prescription sociale au Canada : la promotion de la santé en action, 50 ans après le rapport Lalonde
Authors: Mulligan Kate , Card Kiffer G. , Allison Sandra
Published: June 2024

Le rapport Lalonde, publié en 1974 par le ministre canadien de la Santé nationale et du Bien-être social, a fait oeuvre de pionnier en matière de santé publique au Canada en reconnaissant que les déterminants de la santé vont bien au-delà des services de soins de santé. Cinquante ans plus tard, ce numéro spécial de Promotion de la santé et prévention des maladies chroniques au Canada montre comment on peut agir sur les déterminants de la santé en amont au moyen d’une nouvelle intervention appelée « prescription sociale ». La prescription sociale oriente les patients vers des ressources communautaires qui correspondent à leurs priorités personnelles. Elle favorise ainsi un changement de paradigme par lequel l’approche de promotion de la santé n’est plus axée sur les déficits mais sur les forces. La première partie de ce numéro porte sur la croissance rapide de la prescription sociale et ses applications variées au Canada, que ce soit des initiatives ciblant diverses populations ou des interventions privilégiant le contact avec la nature, les arts, l’activité physique ou encore la connectivité sociale. Les contributions d’un large éventail de partenaires (chercheurs, professionnels de la santé et membres de la communauté, etc.) explorent l’adaptabilité de la prescription sociale à différents groupes, soulignent le rôle que jouent la communauté et les expériences vécues dans la recherche et signalent également la nécessité d’un plus grand nombre d’études sur l’efficacité et les résultats de la prescription sociale. Les études de cas présentées prouvent l’existence d’avantages tangibles sur les plans de l’équité en santé et de l’accès aux services sociaux. Ce numéro ne reflète pas seulement la portée et l’incidence actuelles de la prescription sociale au Canada : il jette aussi les bases de son évolution future et de son intégration dans les pratiques de santé en général.
УДОСКОНАЛЕННЯ НОРМУВАННЯ ВИТРАТ НА ЕЛЕКТРОЕНЕРГІЮ НА ГІРНИЧОРУДНИХ ПІДПРИЄМСТВАХ З УРАХУВАННЯМ ДИНАМІКИ ЕЛЕКТРОСПОЖИВАННЯ
Authors: Кочура Д.В.
Published: June 2024

Розроблено економіко-математичні моделі нормування питомих витрат електроенергії на гірничорудних та переробних підприємствах, рекомендовано удосконалити методику розрахунків індивідуальних та групових норм витрат електроенергії з урахуванням динаміки електроспоживання. Одержано аналітичні залежності сталої та динамічної складової питомих витрат електроенергії на гірничорудному підприємстві від логістичних параметрів постачання сировини: періоду та обсягів постачання, продуктивності та енергоефективності технологічного обладнання, що дозволило поділити індивідуальні та групові норми витрат електроенергії на три складові: норми загальних витрат, норми умовно-постійних витрат, норми витрат на динаміку електроспоживання. Рекомендовано удосконалити на цій основі методику нормування витрат на електроенергію на гірничорудному підприємстві.
ВПЛИВ ШТУЧНОГО ІНТЕЛЕКТУ НА ЦИФРОВУ ЕКОНОМІКУ: ВИКЛИКИ ТА МОЖЛИВОСТІ
Authors: Лисий В.М.
Published: June 2024

У статті обґрунтовано потенціал штучного інтелекту для автоматизації процесів, покращення якості продуктів та послуг, а також стимулювання інновацій та розвитку нових технологій. Одночасно розглядаються ризики, пов'язані з впровадженням штучного інтелекту, такі як втрата робочих місць, проблеми з безпекою даних та етичні аспекти. Аналізуються потреби у розробці стратегій управління ризиками та максимізації переваг від використання штучного інтелекту. Крім того, в статті розглядається вплив штучного інтелекту на економічний розвиток, зокрема на зміну ринку праці, конкурентоспроможність країн та глобальну економічну динаміку.
ВПЛИВ МІГРАЦІЙНИХ ПОТОКІВ НА ДИНАМІКУ РОБОЧОЇ СИЛИ ТА ЇХ РОЛЬ У ФОРМУВАННІ ЕКОНОМІЧНОГО ЛАНДШАФТУ УКРАЇНИ
Authors: Ерфан В.Й. , Вінце О.Й.
Published: June 2024

У статті висвітлено та подано людський капітал, який є ключовим фактором у соціально-економічному розвитку країни, підвищенні конкурентоспроможності національної економіки і забезпеченні належного добробуту домогосподарств, так як, умовою необхідною для прогресу Ураїни є формування потужного економічного потенціалу та його реалізація через підтримку реального економічного зростання. Цей процес, серед інших аспектів, базується на ефективній мінімізації безробіття та спрямованості суспільства на досягнення повної зайнятості.В перспективі, Україна стоїть перед важливим завданням відновлення та зміцнення людського капіталу у післявоєнний період. Внаслідок війни зруйновано тисячі виробничих об’єктів та мільйони робочих місць, а деякі з них вже ніколи не будуть відновлені. Однак вимоги щодо конкурентоспроможності вимагають не лише відновлення старих виробничих можливостей, стандартів і технологій, але й формування нового покоління працівників, здатних ефективно працювати в сучасних інформаційних та технологічних умовах. Це передбачає важливе наповнення українського економічного середовища відповідним рівнем кваліфікованих трудових ресурсів.
РОЛЬ МІЖНАРОДНОГО СПІВРОБІТНИЦТВА У РОЗВИТКУ СІЛЬСЬКОГО ГОСПОДАРСТВА
Authors: Могіш О.М. , Михайлюк О.Б.
Published: June 2024

Для підвищення конкурентоспроможності та збільшення валютних надходжень Україні необхідно перейти від екстенсивного до інтенсивного типу аграрного виробництва. Це передбачає налагодження тісного міжнародного економічного співробітництва з іншими країнами світу, починаючи від міжнародної торгівлі і закінчуючи обміном технологіями у галузі сільського господарства. Без належно налагодженого та продуктивного міжнародного економічного співробітництва, включаючи залучення інвестицій, Україна не зможе зайняти відповідне місце на світовому ринку аграрної продукції та продовольства, а також ефективно використати свій аграрний потенціал для забезпечення стабільного економічного зростання.
cultura da sentença
Authors: Vavgenczak Juliana , Ningeliski Adriane de Oliveira
Published: June 2024

O presente trabalho tem por objetivo abordar as dificuldades enfrentadas pela mediação e conciliação âmbito do Poder Judiciário Brasileiro, tendo em vista uma sociedade habituada a gerir seus conflitos por meio da busca da decisão de um terceiro, o que dificulta a efetivação dos meios de solução de conflitos consensuais. Para tanto, foi utilizado método de abordagem dedutivo, uma vez que se parte da premissa que a cultura à sentença instalada no Brasil prejudica a utilização da mediação e da conciliação. Ainda, objetiva-se analisar a conciliação e mediação e a dificuldade de sua efetivação no âmbito do Poder Judiciário, em que sua grande importância da resolução dos conflitos. Com a presente pesquisa, conclui-se que a mediação e conciliação, apesar dos avanços legislativos, ainda enfrentam obstáculos no sistema do Poder Judiciário Brasileiro, seja pela ausência de estrutura e de pessoal capacitado para realizar as audiências, ou pela falta de conhecimento e de confiança da sociedade nesse método de resolução de conflitos, porque já habituada a buscar a figura do juiz para decidir os conflitos.
Effect of selected bacteria of the genus Pseudomonas on the quality of raw cow’s milk
Authors: Kováčová M. , Výrostková J. , Regecová I. , Dudriková E. , Zahumenská J. , Marcinčák S.
Published: June 2024

Pseudomonas spp. are a psychrotrophic species associated with milk spoilage caused by its enzymatic activities. The aim of this study was to identify Pseudomonas spp. in raw cow’s milk and to investigate their associated enzymatic properties and the ability to produce pyoverdine pigment. For microbiological analysis, 2 ml of milk samples was taken in sterile sample boxes. Milk sampling was carried out according to the principles of STN EN ISO 707. By identification using the PCR method, of n=320 samples of raw cow milk a total of 73 isolates of Pseudomonas spp. were identified as P. putida (34.25%); P. fragi (13.70%); P. lundensis (9.59%) and Pseudomonas spp. (42.47%). Proteolytic activity determined at a temperature of 7°C was positive from n=20 selected isolates of Pseudomonas spp. (60%) isolates and a temperature of 25°C was positively detected (85%). Lipolytic activity determined at a temperature of 7°C was confirmed in 35% of isolates and a temperature of 25°C it was confirmed in 70% isolates. Pyoverdine pigment production was detected in 65% of isolates. The results reveal the enzymatic activity of Pseudomonas spp. present in raw cow’s milk and its spoilage potential at different temperatures in relation to pigment production.
Evaluation of darbepoetin therapy on platelet count and function in healthy cats and cats with surgically induced chronic kidney disease
Authors: De Lombaert Mélissa C. M. , Schmiedt Chad W. , Lourenço Bianca N. , Tarigo Jamie L. , Hodges Katie M. , Brainard Benjamin M.
Published: June 2024

OBJECTIVE

To evaluate the effects of darbepoetin on platelet population and reactivity in healthy cats (HCs) and azotemic cats with remnant kidney (RK) model–induced chronic kidney disease.

ANIMALS

12 purpose-bred domestic shorthair cats (n = 6 HCs and n = 6 RK).

METHODS

In this pilot study, all cats received darbepoetin (1 µg/kg, SC) on days 0, 7, and 14. Blood was sampled at baseline and on days 3, 10, 15, 17, 20, and 21. At each time point, a CBC was performed, platelet aggregometry was assessed by impedance and optical methods, and platelet P-selectin (CD62P) was quantified before and after thrombin stimulation. Additionally, reticulated platelets were quantified using both thiazole orange staining and proprietary analysis by the CBC analyzer. For RK cats, systemic blood pressure (BP) was serially measured.

RESULTS

No adverse effects of darbepoetin were seen. There was no statistically significant change in platelet count between or within groups at any time point. Hematocrit increased significantly over time in the RK but not the HC group. RBC reticulocyte numbers in both groups increased over time. Reticulated platelet percentage did not increase in either group. Differences in platelet reactivity within or between groups were not seen in the aggregometry or flow cytometric assessments. In RK cats, indirect BP did not significantly change during the study.

CLINICAL RELEVANCE

This preliminary investigation did not find evidence that darbepoetin administration impacted platelet number, reactivity, nor reticulated platelet count. Anemic RK cats experienced increased hematocrit and RBC reticulocytes as expected with darbepoetin therapy.
Algorithmic Performance Management in Higher Education: Viva! 365 Ways of Surveillance
Authors: Heemsbergen Luke , Krebs Shiri , Gorur Radhika , Maddox Alexia
Published: June 2024

This paper maps the emergence and consequences of automated Algorithmic Performance Management (APM) in the context of higher education. After reviewing the evolution of productivity management in academia, it argues that surveillance via APM shifts expectations not just about effectiveness at work but also about how work, and the good worker, come to be defined. In our paradigmatic case study of Office 365, we specify how the automated surveillance of workforce practices are deployed to redefine productivity in higher education: productive workers become good data subjects as well as producers of papers, grants, and other traditional outputs of success. Our analysis suggests performing well at work is managed in and by the platform via logics of the surveillance of wellness, time-regulation, and social connectivity to influence, manage, and control workers. We critique these automated performance measures in terms of platform capitalism, noting Office 365’s Viva Insights function as a telematic device of surveillance. The final section of the paper places these trends in Australia’s socio-legal context by showing how Viva is insufficient for considering performance given the range of practices that constitute “academic work,” including but not limited to the need for unmonitored activity. Yet, we observe that currently little can be done about Office 365’s surveillant presence given a regulatory regime that by and large excludes productivity surveillance from the scope of regulated surveillance activities.
Studying Surveillance AI-cologies in Public Safety: How AI Is in the World and the World in AI
Authors: Jacobs Gabriele , Van Houdt Friso , Coons Ginger
Published: June 2024

Technological surveillance for the sake of safeguarding public safety (e.g., cameras, sensors, mobile phones, OSINT) pervades the lives of individuals on many levels. In this article, we advance the idea that the addition of AI changes the way surveillance ecologies function and thus deserves to spawn its own concept: the surveillance AI-cology. Surveillance AI-cologies are made up of interconnected collections of disparate actors (technological, human, more-than-human, organisational, etc.), all implicated in AI-aided surveillance tasks. They contain not only the usual complexities of any technological ecosystem but also the added complexity of AI, with emergent characteristics, both technically and socially. We argue for the utility of multi-faceted perspectives in doing work within AI-cologies, and we describe (anthropologically inspired) methodology for understanding and unpacking AI surveillance ecosystems. The development of democratically controlled AI surveillance requires the systematic consideration of ethical, legal, and social aspects (ELSA) within the quintuple helix (public, private, civil society, academia, nature). We stress the relevance of clearly defining which perspectives of the quintuple helix are considered in AI surveillance, and which not, to achieve a transparent set of (ELSA) values that guide AI surveillance development and implementation. We provide an example of the way we have developed and applied (some of) these methodologies in the context of a test-site for the development and application of smart city technology, a so-called “Living Lab.” Here we take the stance of active involvement of academics as “critical friends” into complex innovation and assessment processes. Together with our conversation partners in the field, we tease out and reflect upon the (public safety) values embedded in the setup of the Living Lab we explore. We end with a call to understand surveillance AI-cologies not as a problem to be solved, but as a continuing process to be discussed among highly diverse stakeholders.
Exploring the Digital Maze: Unveiling Information Literacy within Moroccan English Department Students with a Focus on Developing a Research Strategy
Authors: Idabdallah Abdelhadi  , Brigui Hind
Published: June 2024

This study explores the realm of information literacy amongst Moroccan English department students, unravelling the intricacies of their abilities in developing a research strategy. Getting data from the Standardized Assessment of Information Literacy Skills (SAILS) test, the research scrutinizes the performance of undergraduate, graduate, and doctoral students. The focus on the specific skill set of developing a research strategy sheds light on the students' competencies in areas such as conferring with instructors, identifying research topics, and understanding the role of desired end products in information retrieval. The findings reveal nuanced strengths and weaknesses among students at different academic levels. This exploration not only contributes to the understanding of information literacy within the Moroccan English departments' context but also provides insights for curriculum designers and faculty seeking to enhance students' proficiency in navigating the digital information landscape.
Recreational Practices and Employee Performance in Non-Governmental Organizations (NGOs) in Kenya
Authors: Protus Lumiti  , Dr. Susan Wekesa  , Dr. Mary Omondi  , Dr. George Orwa
Published: June 2024

Employee welfare practices in organizations, which involve offering various recreational programs in the workplace, are crucial for enhancing motivation and increasing performance among staff members. Therefore, the primary aim of this research was to determine the relationship between recreational activities and employee performance in Kenya while also considering the moderating influence of top management commitment on employee performance. The study utilized a cross-sectional survey approach that incorporated both qualitative and quantitative methods. The research population consisted of 14,323 NGO employees in Nairobi County, Kenya, with 403 participants, including top managers, middle-level managers, and lower-level managers. The selection of respondents was done through stratified, simple random, and purposive sampling techniques. Primary data were collected through questionnaires, while secondary data were obtained from peer-reviewed books, articles, and journals. The study was grounded in relevant theories such as Maslow's hierarchy of needs, Herzberg's two-factor theory, and Human Relations Theory. A pilot study was conducted to ensure the reliability and validity of the research tools. Data analysis was carried out using the Statistical Packages for Social Sciences, version 25, with inferential and descriptive statistics, including frequencies, means, correlations, and multiple linear regression. The findings of the study were presented through pie charts, graphs, and tables. The results indicated a positive and significant relationship between recreational practices like staff parties, team building, and sports events and employee performance. Moreover, it was found that top management's communication, policy development, and budget allocation significantly moderated the relationship between recreational practices and employee performance. Additionally, a linear relationship was observed between the independent and dependent variables. In conclusion, the study emphasized the importance of recreational practices in enhancing employee performance, especially when supported by top management commitment.
The development of the integration of the Union State at the present stage
Authors: Zakharov A. N.
Published: June 2024

The article is devoted to the study of the current state of integration of the Union State in the context of the modern transformation of the world order. The article identifies the reasons for the rapprochement between Russia and Belarus which made it possible to create and develop the integration project. Despite the objective difficulties, the two states have been successfully developing joint economic projects for a long time. Special attention is paid to the identification of external factors affecting the development of the Union State. Since the creation of the Union State western countries have pursued a policy aimed at weakening the potential of the integration association. The article examines the last years of the Union State’s activity, reveals the impact of sanctions pressure on Russia and Belarus, and analyzes the steps taken by the leaders of the two countries to further develop the integration project.
The Survivors: Syrian Young Adult Refugee Experiences Navigating the Quebec Education System
Authors: Maraj Arianne , Sherab Domenique , Calderon-Moya Milagros , Ghosh Ratna
Published: June 2024

Canada resettled over 74,000 Syrian refugees since 2015. However, education programs lack awareness needed to successfully promote refugee academic integration. Little research focuses on young adult refugees (YARs) aged out of traditional schools due to asylum displacement and disrupted education, left with adult education schools as their only alternative to complete high school. Drawing upon 29 semi-structured interviews with Syrian YARs in Montreal, findings suggest that this subgroup is unintentionally excluded by educational policy-makers. Although YARs are survivors, their drive was found to be insufficient when confronted with systemic barriers that prevent at-risk students from proceeding smoothly through school to reach their highest potential.
Providing equity-oriented care and services: Perspectives of primary care nurses working in Nunavik Inuit communities
Authors: Delli Colli Anne-Renée , Blanchet Garneau Amélie
Published: June 2024

Health inequities experienced by Indigenous Peoples are the consequence of unbalanced structural determinants of health, mainly due to systemic racism and colonialism. Primary care registered nurses face multiple challenges, including lacking resources to care for these communities and address health inequities. This study aimed to explore equity-oriented care and services from the perspectives of primary care registered nurses working in Nunavik (Northern Quebec, Canada) Inuit communities. We used a critical postcolonial perspective and an interpretive descriptive design. We conducted semi-structured interviews with ten participants and thematically analyzed the data collected. The results showed dynamic conceptualizations of equity-oriented care and services that shaped how participants see the northern colonial context, the healthcare accessibility, and the nursing care approach within Inuit communities. From these findings, we call for accountability measures like antiracist policies to promote transformational changes toward health equity.
Editorial
Authors: General Editor
Published: June 2024

.
Reflexiones alrededor de las epistemologías y las ontologías en las ciencias ambientales
Authors: Peña Miguel , Floréz Fernando , Cubillos Quintero León Felipe , Duque Andres , Portela Guarín Hugo , Tobar Q Javier , Ortega Santos Antonio , Ortiz Báez Pedro Antonio
Published: June 2024

Este libro reúne textos de profesores del Doctorado Interinstitucional en Ciencias Ambientales de la Universidad del Valle, la Universidad Tecnológica de Pereira y la Universidad del Cauca; además, de profesores invitados de México y España. El objetivo principal de la formación doctoral es preparar investigadores de alto nivel, vinculados al sector ambiental, que estarán en capacidad de trabajar en equipos interdisciplinarios desde una dimensión tecnológica, ética, social, política y económica; para generar conocimientos y plantear alternativas de solución a los problemas asociados con el medio ambiente, buscando la sostenibilidad de la relación entre naturalezas y culturas. Los diferentes aportes consignados en los capítulos que componen este texto permiten nutrir, no agotar, la discusión generada sobre el estatuto académico de las ciencias ambientales, abordado desde diferentes disciplinas que integran visiones desde las denominadas como ciencias duras hasta los aportes de las ciencias sociales, y el reconocimiento de los saberes ancestrales que diferentes grupos étnico-territoriales han creado en su proceso histórico de configuración social, con referencia a su concepción de naturaleza. Su enfoque ofrece una visión crítica, amplia y plural sobre diferentes formas de abordar las relaciones entre los humanos y su entorno, como el deterioro generado al medio ambiente, que pasó de ser objeto de conocimiento a un actor fundamental de la realidad. Esperamos que los lectores del libro saquen sus propias conclusiones y establezcan una perspectiva propia en la búsqueda de soluciones al impacto negativo de la acción humana sobre el planeta.
Successful Management of Adenine Phosphoribosyl Transferase Enzyme Deficiency in Renal Transplantation: A Case Report
Authors: Malavade Praveen Vijaykumar
Published: June 2024

Adenine phosphoribosyltransferase (APRT) enzyme deficiency is a rare inborn metabolic error causing an accumulation of 2,8 dihydroxyadenine (DHA), leading to kidney stones and crystal nephropathy. If untreated, it progresses to end stage renal disease (ESRD) with a subsequent risk of crystal nephropathy recurrence post-renal transplantation. Recurrence post-transplant can be prevented, and allograft outcomes can be improved if treatment with an xanthine oxidoreductase (XOR) inhibitor is initiated before or at the time of kidney transplantation. We describe a case involving a 24-year-old male with ESRD, found to have APRT enzyme deficiency during transplant evaluation, successfully managed with pre- and post-transplant XOR inhibitors to prevent recurrence, resulting in a positive allograft outcome.
Progesterone attenuate autism-like-phenotype through modulation of cerebral inflammation and oxidative stress
Authors: Mirza Roohi , Sharma Poonam , Kulkarni G. T. , Sharma Bhupesh
Published: June 2024

Objectives:

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that characterises repetitive behaviour and impairment in social communication as well as interaction. The complex aetiology of ASD involves multiple genes, epigenetic mechanisms and environmental factors. Propionic acid (PPA) is observed to be well associated with behavioural and biochemical phenotypes akin to ASD. This study evaluates the potential effect of progesterone in PPA-induced ASD phenotype.

Materials and Methods:

PPA (250 mg/kg, po) was administered to induce ASD-like behavioural and neurobiochemical alterations in Albino Wistar rats from post-natal day 21st to 23rd. Rats were observed for locomotor activity (open filed apparatus), exploratory behaviour (hole board apparatus- no. of rearing, latency to first poke and hole poking), stereotypy behaviour (self-grooming) and biochemical parameters (interleukin-6, tumour necrosis factor-alpha, glutathione and thiobarbituric acid reactive substance).

Results:

Post-natal PPA administration resulted in hyperlocomotion, repetitive behaviour and a decrease in exploratory activity. Furthermore, an increase in inflammation and oxidative stress markers was observed in the brain regions of PPA-administered rats. Progesterone (4 mg/kg and 8 mg/kg) administration was observed to attenuate postnatal PPA-induced impairments in experimental animals.

Conclusion:

Progesterone (4 mg/kg and 8 mg/kg) administration may protect against behavioural and biochemical alterations that are associated with ASD.
БИОХИМИЧЕСКИЕ ИССЛЕДОВАНИЯ ВОДОРАСТВОРИМЫХ ПОЛИСАХАРИДОВ, ВЫДЕЛЕННЫХ ИЗ РАСТЕНИЙ
Authors: Лхагвасурэн О. , Туваанжав С.
Published: June 2024

В данном исследовании проводили биохимический анализ в некоторых сельскохозяйственных культурах. При этом определяли антиоксидантную и антибактериальную активность у водорастворимых полисахаридов в растениях ланцея тибетская (Lancea tibetica), козелец растопыренный (Scorzonera divaricate), горечавка холодная (Gentiana algida Pall) и недоспелка копьевидная (Parasenecio hastatus). При концентрации 10 мг/мл полисахаридов не образовывалась зона подавления роста бактерий во всех исследуемых культурах. В расчете антиоксидантной активности значения Ic50 у полисхаридов Lancea tibetica составляли более 200 мкг/мл, Scorzonera divaricate – 111,4 ± 0.17 мкг/мл, Gentiana algida Pall более 200 мкг/мл, Parasenecio hastatus – 31,06 ± 2.3 мкг/мл.
ANALYSIS ON CHINESE AUTOMOBILE ENTERPRISES EXPLOITING RUSSIAN MARKET
Authors: Арай А.
Published: June 2024

Автомобильная промышленность признана отраслью с высокой степенью промышленной значимости, автомобильная промышленность является «отраслью в отрасли», занимающей очень важное положение в национальной экономике. Поскольку Китай является слабым рынком экспорта автомобилей, у России широкие рыночные перспективы. В 2021 и 2022 годах Россия ввела ряд мер по стимулированию автомобильного рынка и вступила в ВТО в конце 2021 года. В статье исследуется текущая ситуация на российском рынке и потребление автомобилей на основе введения соответствующей политики в России и текущей ситуации с экспортом китайской автомобильной продукции в статье анализируются проблемы, существующие в китайской автомобильной продукции и на предприятиях-экспортерах в Россию. Выдвинуто пять предложений для китайских автомобильных предприятий, эксплуатирующих российский автомобильный рынок.

The automobile industry is recognized as an industry with a high degree of industrial relevance, and the automobile industry is an «industry within an industry», occupying a very important position in the national economy.As China’s impotant automobile export market, Russia enjoys a broad market prospect. In 2021 and 2022, Russiaintroduced several policies to stimulate automobile market and it entered the WTO at the end of 2021. Under suchcircumstances, the paper studies the current situation of Russian market and automobile consumption. 0n the base of theintroduction of relative polices in Russian and the current export situation of Chinese automobile products, the paper analyzesthe problems existing in Chinese automobile products and exporting enterprises to Russia. At last, five suggestions have beenput forward for Chinese automobile enterprises exploiting Russian automobile market.
EFFICIENCY OF PHOSPHOGYPSUM APPLICATION ON SODDY-PODZOLIC SOILS IN WINTER WHEAT CROPS
Authors: Аканова Н.И. , Холомьева Л.Н. , Плескачев Ю.Н. , Можаренко М.Н.
Published: June 2024

В статье рассмотрена возможность использования побочного продукта производства фосфорной кислоты – фосфогипса (ФГ) на кислых дерново-подзолистых почвах в качестве мелиоранта и комплексного фосфор-кальций-серосодержащего минерального удобрения. В среднем за два года внесение 1 т/га ФГ в сравнении с контрольным вариантом обеспечило получение прибавки урожая зерна озимой пшеницы 0,29 т/га, или 8,8%, 2 т/га ФГ – 0,36 т/га, или 10,9% и 3 т/га ФГ – 0,40 т/га, или 12,1%. Применение NPK 10:26:26 + 1 т/га ФГ способствовало увеличению урожайности на 1,75 т/га, или 53%, NPK 10:26:26 + 2 т/га ФГ, так же как NPK 10:26:26+ 3 т/га ФГ на 1,82 т/га, или 55,2%. В 1-й год действия ФГ при внесении 2,0 и 3,0 т/га ФГ отмечено достоверное снижение уровня гидролитической кислотности на 0,27 и 0,34 ммоль экв/100 г почвы. Отрицательного влияния ФГ на кислотно-основные свойства почв, в том числе подкисляющего действия ФГ и увеличения гидролитической кислотности почвы не выявлено. Эколого-токсикологическая оценка применения ФГ в дозах 1,0–3,0 т/га не выявила достоверного увеличения концентрации подвижной формы тяжелых металлов, превышающей ПДК в почве.

The article discusses the possibility of using phosphogypsum (FG), a by-product of phosphoric acid production, on acidic soddy-podzolic soils as an ameliorant and a complex phosphorus-calcium-sulfur-containing mineral fertilizer. On average, over two years, the application of 1 t/ha of FG in comparison with the control variant provided the increase in winter wheat grain yield of 0.29 t/ha, or 8.8%, 2 t/ha of FG 0.36 t/ha, or 10.9%, and 3 t/ha FG – 0.40 t/ha, or 12.1%. The use of NPK 10:26:26 + 1 t/ha FY contributed to the increase in yield by 1.75 t/ha, or 53%, NPK 10:26:26 + 2 t/ha FG, as well as NPK 10:26:26 + 3 t/ha FG by 1.82 t/ha, or 55.2%. In the 1st year of FG action, at the application of 2.0 and 3.0 t/ha of FG, a significant decrease in the level of hydrolytic acidity by 0.27 and 0.34 mEq/100 g of soil was noted. The negative effect of FG on the acid-base properties of soils, including the acidifying effect of FG and an increase in the soil hydrolytic acidity, was not revealed. Ecological and toxicological assessment of the use of FG at doses of 1.0–3.0 t/ha did not reveal a significant increase in the concentration of the mobile form of heavy metals, exceeding the maximum permissible concentration for soils.
Enabling ionic transport in Li3AlP2 the roles of defects and disorder
Authors: Hu Ji , Squires Alexander G. , Kondek Jedrzej , Johnson Michael J. , Youd Arthur B. , Vadhva Pooja , Paul Partha , Withers Philip J. , Michiel Marco Di , Keeble Dean S. , Hansen Michael Ryan , Scanlon David O. , Rettie Alexander J.E.
Published: June 2024

Lithium phosphides are an emerging class of Li+ ion conductors for solid state battery applications. Despite potentially favorable characteristics as a solid electrolyte, stoichiometric crystalline Li3AlP2 has been reported to be an ionic insulator. Using a combined computational and experimental approach, we investigate the underlying reasons for this and show that ion transport can be induced via defects and structural disorder in this material. Lithium vacancies are shown to promote diffusion, and a low barrier to Li+ hopping of 0.2-0.3 eV is revealed by both simulations and experiment. However, polycrystalline pellets exhibit low ionic conductivity (≈10−8 S cm−1) at room temperature, attributed to crystalline anisotropy and the presence of resistive grain boundaries. These aspects can be overcome in nanocrystalline Li3AlP2, where ionic conductivity values approaching 10−6 S cm−1 and low electronic conductivities are achieved. This approach, leveraging both defects and structural disorder, should have relevance to the discovery of new, or previously overlooked, ion conducting materials.
Bidentate Phosphine Ligand Impacts on Previously Inaccessible 5-Membered N-Heteroaryne Formation and Functionalization
Authors: Plasek Erin , Belli Roman , Kavaguti Douglas , Roberts Courtney
Published: June 2024

5-Membered N-heteroarynes have long been considered synthetically inaccessible; however, we recently reported the use of a bisphosphine-ligated nickel center to stabilize and enable the formation of these otherwise unobtainable intermediates. Moti-vated by this success, we were compelled to study the role of the ancillary phosphine in aryne formation and reactivity. Here-in, a set four bidentate phosphine ligands with altered phosphine substituents and backbone length are interrogated for their competence as ancillary ligands for 5-membered N-heteroaryne formation. We determined that ligands with phenyl phosphine substituents or linker lengths longer than three carbons were unsuitable for this purpose, while ligands having alkyl phos-phine substituents and one, two, or three carbon linkers allowed for successful aryne formation. Reactivity studies using 2-PyZnBr as a nucleophilic coupling partner revealed intriguing regioselectivity enhancement (up to >20:1 r.r.) when utilizing ligands with altered linker lengths. We hypothesize that regioselectivity can be traced back to structural differences between these Ni-aryne complexes, as evidenced by crystallographic characterization.
Large Language Models for Inorganic Synthesis Predictions
Authors: Kim Seongmin , Jung Yousung , Schrier Joshua
Published: June 2024

We evaluate the effectiveness of pre-trained and fine-tuned large language models (LLMs) for predicting the synthesizability of inorganic compounds and the selection of precursors needed to perform inorganic synthesis. The predictions of fine-tuned LLMs are comparable to—and sometimes better than—recent bespoke machine learning models for these tasks, but require only minimal user expertise, cost, and time to develop. Therefore, this strategy can serve both as an effective and strong baseline for future machine learning studies of various chemical applications and as a practical tool for experimental chemists.
Microfluidic platform integrating Caco-2 spheroids-on-chip for real-time investigation of intestinal epithelial interaction with bacterial extracellular vesicles
Authors: Calzuola Silvia Tea , Pinamonti Debora , Rizzotto Francesco , Malet-Villemagne Jeanne , Henry Céline , Péchaux Christine , Blondé Jean-Baptiste , Roy Emmanuel , Manzano Marisa , Lakisic Goran , Truchet Sandrine , Vidic Jasmina
Published: June 2024

Campylobacter jejuni is the most common cause of foodborne gastroenteritis in humans with about 550 million annual infections worldwide. The extracellular vesicles (EVs) of C. jejuni have an important impact during pathogenicity but their role in invasion of the host intestinal epithelial cells remains largely unknown. In vitro models lack the complexity of tissue and fail to replicate the dynamic interactions between EVs and human intestinal epithelial cells accurately, while animal infection models bring ethical concerns. To bridge this gap, we propose a microfluidic platform integrated with an impedimetric sensor for real-time monitoring of C. jejuni EVs' interaction with human intestinal epithelial cells. When cultured in this microfluidic device, Caco-2 epithelial cells underwent spontaneous 3D morphogenesis and spatially organised in spheroid-like structures. Functional assays revealed that C. jejuni secretome and EVs have a significant cytotoxic effect on Caco-2 cultured on plates. However, 3D Caco-2 spheroids showed increased resistance to the toxicity of secreted virulence factors of C. jejuni. By combining impedance spectroscopy and microscopic observation, the platform allowed real-time monitoring of cellular spatial growth and sensitive detection of the Evs' ability to reach and damage intestinal epithelial cells organised in 3D morphologies. Thus, the developed microfluidic device offers a promising platform for investigating host-microbe interactions and may have a broad impact on biomedical research on gastroenteritis.
Dialogando com os conceitos de Turismo de Base Comunitária e Turismo Criativo
Authors: Albuquerque Mariene Cavalcante Borba de , Nascimento Felipe Gomes do , Nóbrega Wilker Ricardo de Mendonça
Published: June 2024

O objetivo deste trabalho foi refletir como a gestão de Turismo de Base Comunitária tem utilizado estratégias do turismo criativo, para incrementar os serviços turísticos oferecidos em sua localidade. O estudo resultou de uma revisão não sistemática de literatura baseada em revisões recentes e obras seminais dos conceitos analisados e estudos de caso relacionados ao tema. O Turismo de Base Comunitária surge da ideia de desenvolver um Turismo de Base Local, em que a população residente deve ser a principal beneficiada, planejando, conduzindo e mantendo a prática turística dentro de seu território. O estudo apresenta alguns estudos de caso, presentes na literatura, em que comunidades, com gestão do Turismo de Base Comunitária, tem utilizado princípios da Economia criativa para incrementar os serviços oferecidos, concluindo que o chamado turismo criativo pode ser uma opção para este fim.
Turismo rural, sustentabilidade e educação ambiental
Authors: De Lourdes Ivonete do Carmo
Published: June 2024

Este estudo teve como objetivo caracterizar as publicações que discutem sobre o turismo rural e sua relação com a educação ambiental e sustentabilidade. Para tanto, utilizou-se da revisão sistemática com metanálise com tipo de pesquisa exploratório e abordagem para análise mista dos dados, ou seja, qualitativa e quantitativa. Para isto, utilizou-se como apoio o software Ucinet®. A coleta de dados foi por meio da revisão bibliográfica dos artigos selecionados nas bases Web of Science. Os resultados encontrados apontam que os trabalhos pesquisados consideram o turismo de baixo carbono como uma forma alternativa ao turismo convencional, com menor impacto ambiental. Os investimentos em infraestrutura podem promover a redução da pobreza, impulsionar o desenvolvimento econômico, aumentar empregos e renda dos mais pobres, ainda os autores destacam que, incluir as comunidades é fundamental para o caminho que visa aumentar a sustentabilidade social e contribuindo para sistemas de turismo socialmente sustentáveis  e inclusivos.
Cycling tourism and cycling sport events tourism on the Estrada Parque Piraputanga/ Mato Grosso do Sul, Brazil: possibilities for local development
Authors: Romero Bandeira Serrou Camy Larissa , De Oliveira Belino Bonfim Izac , Scheuer Luciane
Published: June 2024

Cycling is a sports and leisure activity with accelerated growth throughout the national territory. In Brazil, there is a lack of data denoting the economic potential of this sport modality, as well as the sectors indirectly affected, such as tourism. From this assumption, this research had as a general objective to identify the perception of cyclists about the tourism potential of APA Estrada Parque Piraputanga, an Environmental Protection Area, for the development of cycling tourism and cycling sport events tourism. The procedures used initially in this investigation were based on a bibliographic research and documental analysis, followed by an exploratory analysis in loco. After initial procedures, this research was based on a quali-quantitative approach, with the application of an on-line questionnaire with cyclists using the snowball technique. The questionnaire had closed and open questions, which were analyzed by simple sampling, as well as the application of the technique of Content Analysis (CA) of Bardin (2011) for the open question. As result, in the perception of the cycle tourists there is need for investment in improving the infrastructure for tourism in general. Finally, it was detected that APA Estrada Parque Piraputanga has potential for local development through the segment of cycling tourism and cycling sport events tourism.
Gestão pública do município de Petrópolis (RJ)
Authors: Viveiros Luciana , Fratucci Aguinaldo Cesar
Published: June 2024

O artigo apresenta um estudo comparativo dos planos diretores de turismo do município de Petrópolis. Para tanto, a análise compreendeu: a) Plano Imperial desenvolvido em 1998, com horizonte temporal de 10 anos, desenvolvido pela PETROTUR (Empresa de Turismo de Petrópolis) e Secretaria Municipal de Indústria, Comércio e Turismo e, b) Plano Petrópolis Imperial, desenvolvido em 2009, pela Fundação de Cultura e Turismo de Petrópolis, também com horizonte temporal de 10 anos. Metodologicamente, utilizou-se de pesquisa bibliográfica e documental e da ferramenta de análise de conteúdo. Como principais resultados destaca-se que os dois planos apresentam semelhanças do ponto de vista metodológico e propostas de desenvolvimento pouco detalhadas para serem operacionalizadas. A ausência de planos operacionais detalhados dificulta o monitoramento e acompanhamento da sua execução e dos respectivos resultados alcançados.
Palavras-chave: turismo; políticas públicas; planejamento turístico; plano diretor; Petrópolis-RJ
Filme da Minha Vida
Authors: Pereira Silveira Vanilson , Cardinale Baptista Maria Luiza , Coelho Barros Roberta
Published: June 2024

O objetivo do artigo é discutir a relação entre cinema e turismo, apresentando as locações do filme “O Filme da Minha Vida” (2017), gravado na Serra Gaúcha, Região Uva e Vinho. A metodologia segue a perspectiva qualitativa e exploratória, contemplando uma revisão bibliográfica e análise do filme. Em termos de resultados é possível apontar o potencial do filme para promover e divulgar os municípios, exibindo elementos que caracterizam a paisagem urbana e rural. Algumas locações são pontos turísticos, o que pode contribuir para reforçar a imagem dos atrativos, despertar o interesse do espectador e estimular o desenvolvimento do turismo cinematográfico.
Gestão Pública do Patrimônio Histórico
Authors: Moser Giancarlo , Francisco Thiago Henrique Almino , Roecker Rejane
Published: June 2024

O propósito do texto é analisar as relações entre a Gestão Pública do Patrimônio Histórico no Brasil e Identidade Cultural e verificar a pertinência e os desafios dessa relação na legislação e ordenamento jurídico patrimonial brasileiro. Para tanto, trabalha-se com a perspectiva da existência de um patrimônio sentido, vivido e um patrimônio delimitado pelo poder público, sobre o qual se associam conceitos em prol da identidade cultural, promovendo uma reflexão teórica das interfaces estabelecidas entre memória, identidade e patrimônio. Buscaremos entender como esses conceitos são expressos nas iniciativas contemporâneas que visam à valorização do patrimônio histórico cultural.
Turismo LGBTQ+
Authors: Bignardi Neves Christopher Smith
Published: June 2024

Turistas LGBTQ+ (Lésbicas, Gays, Bissexuais, Transexuais, Queers e outras identidades) representam a fonte do pink money, são exaltados pelo mercado por consumirem acima da média heterossexual. Porém, a importância deste público padece da atenção acadêmica. Reflexões sobre sexualidade e turismo provém de poucos pesquisadores que congregam as temáticas. Este artigo de revisão, apresenta uma pesquisa bibliométrica sobre as 1.486 dissertações defendidas nos Programas de Pós-Graduação em Turismo entre os anos de 1997 e 2019 (primeiro semestre), provenientes de doze instituições. Neste artigo são apresentadas as sete dissertações que discorrem a temática do turismo LGBTQ+, que constitui o objeto da análise. O objetivo centra-se em descrever sinteticamente as dissertações, expondo pontos centrais das pesquisas. Considerando há escassez de pesquisas que envolve o público LGBTQ+, as dissertações constituem um promissor instrumento para preencher as lacunas sociais, econômicas e biopolíticas que abarcam os aspectos turísticos.
Creatividad e innovación en estrategias y políticas públicas para el desarrollo de destinos en turismo médico y de salud ante la pandemia
Authors: Zermeño-Flores Sonia Guadalupe , Zizaldra-Hernández Isabel , Delgado-Guzmán José Alfredo
Published: June 2024

La comercialización de los servicios de salud en los mercados internacionales ha generado un fenómeno denominado turismo médico y de salud (TMyS) En sentido es estudio exploratorio con enfoque cualitativo que busca, a través de entrevistas a profundidad como estrategias de recolección de información, construir una red de oportunidades de desarrollo del turismo médico y de salud en la ciudad de San Luis Río Colorado, Sonora. Los informantes son actores gubernamentales, prestadores de servicios turísticos y de salud e investigadores del área, cuyas aportaciones se analizan bajo la metodología de interpretación del discurso con apoyo cualitativo del software Atlas.ti. Las conclusiones permiten demostrar el interés de los actores del sistema turístico y de salud en aplicar diferentes acciones de creatividad e innovación para el desarrollo de la actividad económica, en esta época de pandemia que requiere el diálogo entre las instituciones de poder y los sectores involucrados en su crecimiento.
Gestão turística e potencialidade de desenvolvimento da região do Lago Corumbá IV no estado de Goiás/Brasil
Authors: Alves Borges Amanda , Schreinert dos Santos Ivaneli , Luis Tomazzoni Edegar , Cordeiro Braga Débora
Published: June 2024

O Lago Corumbá IV está localizado na Região Centro-Oeste do Brasil e banha sete municípios do estado de Goiás: Abadiânia, Alexânia, Luziânia, Silvânia, Novo Gama, Corumbá de Goiás e Santo Antônio do Descoberto. O Lago tem potencial turístico, entretanto, as áreas de suas margens não são bem desenvolvidas turisticamente. Desta forma, o objetivo deste artigo é analisar a gestão turística da região do Lago Corumbá IV, com base na visão dos gestores do setor privado e gestores públicos locais. A metodologia é de abordagem qualitativa, foi feito pesquisa bibliográfica sobre o objeto de pesquisa, os dados empíricos foram coletados por meio de entrevistas estruturadas, com posterior análise de conteúdo utilizando o software Iramuteq®. Os resultados evidenciam que todos os municípios apresentam dificuldades na gestão turística, não havendo uma adequada articulação entre o setor público e o setor privado.