bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINICAL STUDIES OF THE STABILITY AND PROCESS OF OSTEOINTEGRATION OF DENTAL IMPLANTS DURING IMMEDIATE AND DELAYED IMPLANTATION
Authors: Grishin Petr , Kalinnikova Elena
Published: February 2021

Subject. Analysis of the literature confirms that there is a definite relationship between surface microstructure, implant geometry, thread design and primary stability, and osseointegration processes. To date, a sufficient number of works on direct and delayed implantation have accumulated. However, there is not enough convincing clinical data on the quantitative assessment of primary stability at different periods of the osseointegration process. Despite the existence of experimental and clinical observations, it seems impossible to make a definite judgment about the mechanism of such a relationship. This chapter presents clinical studies of the stability and osseointegration of dental implants when performing, according to the indications, in 414 patients of direct and delayed implantation using implant systems with different surface microstructures.

Goal. Conduct clinical studies of quantitative indicators of stability and osseointegration of implants with different microstructure of the surface during direct and delayed implantation.

Methodology. For the clinical study of primary stability and the process of osseointegration during direct and delayed implantation with immediate functional loading, implant systems with different surface microstructures were used: Alfa Bio, Mis, Astra-Tech, Dentium, Ostem, Antogher, and also Humana Dental with an innovative surface. Osseointegrated implants have been used to achieve a predictable treatment outcome in clinical cases with partial or complete adentia, as well as in the presence of single, included defects.

Results. There were no significant differences in stability indicators at the time of implant placement in the alveolar bone, depending on the type of implant and the method of implantation.

Conclusions. In the process of integration of the implant into the bone tissue at a later date, the indicators of stability and osseointegration improve. The relationship between the appearance of the implant surface, primary stability and the time of its adaptation was revealed.
Relationship between automated perimetry and Heidelberg retina tomograph, optic coherence tomography and laser polarimetry in moderate to severe glaucomatous eyes
Authors: ASLANCI Mehmet Emin , BAYKARA Mehmet , GÜLER Emre , TİMUCİN Ozgur Bulent , YILMAZ Sami
Published: February 2021

Objectives: To determine the correlations between the measurements obtained with Heidelberg retina tomograph III (HRT III), optic coherence tomography (OCT), and laser polarimetry (GDx) with the indices of automated perimetry (AP) in moderate and severe glaucoma patients.
Methods: Forty-nine eyes of 30 patients were included in the current study and were divided into two groups: 23 eyes with moderate and 26 eyes with severe glaucoma defined by Hodapp-Parrish-Anderson grading system. Pearson’s correlation coefficients were used to evaluate the correlation between the indices of AP including mean deviation (MD) and pattern standard deviation (PSD), and structural parameters of the retinal nerve fiber layer (RNFL) and optic disc acquired by using three devices in both groups.
Results: In moderate glaucoma OCT and GDx measurements were not correlated to MD only the exception of inferior RNFL (r = 0.57, p = 0.007 and r = 0.52, p = 0.008, respectively). Mild to moderate correlations were calculated between the structural parameters of HRT III and AP indices. In severe glaucoma, the most correlated measurements were obtained by OCT compared to the other devices. The correlations for MD were more powerful compared to PSD. Parameters based on the study of the RNFL showed stronger correlations than those of the optic nerve head. No devices showed significant correlations in patients with MD less than -12 dB.
Conclusions: OCT measurements showed the best correlations with the AP indices in both moderate and severe glaucoma patients. However, AP still seems to be more effective in the follow-up of glaucoma progression in more advanced glaucomatous damage.
Relative humidity effect on encapsulation properties of coproducts obtained from wet milling of amaranth grain
Authors: Roa Acosta Diego Fernando , Nieto Calvache Jhon Edinson , Agudelo Laverde Lina Marcela
Published: February 2021

The co-products of the amaranth starch extraction have recently aroused the interest of the industry, mainly due to their functional characteristics. In this paper, the encapsulating efficiencies of starch-enriched fraction (SEF) and native starch (NS) obtained, respectively, by dry or wet milling were studied. The storage humidity effect (11 to 84%, 21 days) on β-carotene retention were evaluated. Significant effects of amaranth protein present in SEF matrix on emulsification and subsequent retention of β-carotene were found. The best encapsulation performance was showed by ball milled starch enriched fraction (SEF-BM) fraction, with up to three times of total β-carotene content in comparison with the NS containing matrices. The glass transition temperature (Tg) of the samples decreased with the increase in relative humidity due to the plasticizing effect of the water. The starch-enriched amaranth fraction showed a high technological potential as an encapsulating agent and its own protein content served as a good emulsifier-stabilizer.
The relationship between individual innovativeness and belonging to different generations
Authors: Savanevičienė Asta , Statnickė Gita
Published: February 2021

Abstract
 
This article, applying the cohort perspective, which views generations simply as collections of people born in a given period of time, analyses the relationship between individual innovativeness and belonging to different generations. The article provides the generation conception, gives a short overview of generational diversity, focuses on generational differences, discusses theoretical aspects of individual innovativeness and analyses individual innovativeness among the representatives of four generations: the Baby Boomers, the Generation X, the Generation Y and the Generation Z.
 
Keywords: Generation, the Baby Boomers, the generation X, the generation Y, the generation Z, individual innovativeness.
Identification of Phytochemicals Compound On the Ethanol Extract ‎of Banana Peel Musa Balbisiana Colla “Kepok Putih” and Musa X ‎Corniculata Lour. “Tanduk”‎
Authors: Wardati Fauchil , Fitriahani Feby , Laily Ainun ‎ Nikmati
Published: February 2021

Indonesia is the largest banana producer in Asia and each year continues to increase its production. The number of banana production in Indonesia reached 4,177,155 tons in 2003 and increased continuously to 6,373,533 tons in 2009. The abundance of banana peel is not comparable with the utilization of a banana peel in the society which has so far not been processed much apart from being animal feed. Two types of bananas that are often processed but the peels have not been optimally utilized yet are “kepok putih” and “tanduk”. Banana peel of “kepok kuning” extract contains alkaloids, flavonoids, quinones, saponins and tannins. However, the phytochemical compounds of banana peel “kepok putih” and “tanduk” have not been widely studied. Thus, this research aims to identify the phytochemical compounds from banana peel of “kepok putih” and “tanduk”. The extraction method which used in this experiment was the maceration method using 96 % ethanol solvent. Based on the test results, which may be obtained, it is known that the ethanol extract of banana peel “kepok putih” contains flavonoids, tannins,  alkaloids, while “tanduk” contains flavonoids, saponins, tannins, and alkaloids
Study of Population and Diversity of Diurnal Avifauna in Coban ‎Tarzan and Coban Kodok Malang-East Java: an Inspiration From Holy ‎Qur’an
Authors: Ahmad‎ Mujahidin , Hanifa Berry ‎ Fakhry , Mulyono Rizky Mujahidin , Abidin Mohammad ‎ Ahlim Ihsan , Pranata Yudha Setya
Published: February 2021

Birds are a very important part of biodiversity. Birds can also be used as indicators of environmental quality because bird diversity is also related to ecosystem balance. This study aims to determine the population and diversity of diurnal birds in Coban Tarzan and Coban Kodok in Malang Regency. The data explained that 17 species of birds found in Coban Tarzan and 17 species of birds also in Coban Kodok respectively. Then the Diversity, Evenness, and Dominance index in Coban Kodok were 2,25; 0.85; 0,15 repectivelty. while in Coban Tarzan were 2,13; 0.83; 0,17 respectively. Overall, Coban Kodok has better values of diversity and both of location have no significant different of evenness and dominance index
DESCARGA SÓLIDA DO RIO ITAJAÍ DO SUL MEDIANTE APLICAÇÃO DO MÉTODO SIMPLIFICADO DE COLBY
Authors: Baucke Alex Sandro , Ferrari Jarbas Cleber , Michel Gean Paulo , Goetten Willian Jucelio
Published: February 2021

O monitoramento hidrossedimentológico é uma ferramenta importante na supervisão a ser realizada em uma bacia hidrográfica, visto que os corpos hídricos são utilizados nos mais variados fins, como abastecimento público, navegação, irrigação, entre outros. Como a sub-bacia do Itajaí do Sul não apresenta este acompanhamento, buscou-se neste trabalho mediante utilização de uma ferramenta computacional, estimar a descarga sólida total diária da sub-bacia em um período de dois anos. Ainda, como item complementar, se estabeleceu uma relação entre a turbidez e a concentração de sedimentos em suspensão. Os resultados para esta relação foram satisfatórios, visto que o coeficiente de determinação encontrado foi de 0,98. Já para a descarga sólida total, devido à ausência de dados durante um curto período, não foi possível obter um valor total para o ano de 2015. Entretanto, em 2014 constatou-se um transporte de sedimentos aproximado na foz do rio Itajaí do Sul de 1,29 milhões de toneladas. Deste modo, com a obtenção desses resultados satisfatórios, acredita-se que este estudo possa contribuir como uma ferramenta de gestão na sub-bacia do rio Itajaí do Sul.
DIAGNÓSTICO DA GESTÃO E GERENCIAMENTO DOS RESÍDUOS DA CONSTRUÇÃO CIVIL (RCC) EM MUNICÍPIOS DA REGIÃO CELEIRO DO RIO GRANDE DO SUL
Authors: Sganderla Maíra Splendor , Bohrer Robson Evaldo Gehlen , Bisognin Ramiro Pereira , Da Silva Danni Maisa , Guerra Divanilde
Published: February 2021

Os Resíduos da Construção Civil, também denominados de entulhos, correspondem à grande quantidade de resíduos produzidos diariamente. O setor da construção civil é um dos maiores geradores de resíduos, devido à falta de controle nas obras. Em virtude ocorre a disposição irregular dos RCC em locais inapropriados acarretando sérios impactos ambientais, afetando a qualidade de vida da população. Sendo assim, verificou-se a necessidade de realizar o diagnóstico de elementos de gestão e gerenciamento dos RCC em municípios da Região Celeiro. Nesta perspectiva, o objetivo do trabalho foi fazer um diagnóstico sobre a gestão e o gerenciamento dos RCC. Para o desenvolvimento do trabalho aplicou-se um questionário com perguntas objetivas ao Poder Público Municipal em municípios da Região Celeiro. Através dos dados obtidos evidenciou-se que 56% dos municípios não são contemplados com um Plano de Gerenciamento dos Resíduos da Construção Civil e 77% não cobram a elaboração do mesmo para aprovação de projetos de novas obras. Contudo, 77% dos municípios possuem áreas licenciadas e pontos de entrega voluntários para disposição final dos RCC. Com o trabalho observou-se que a grande maioria dos municípios entrevistados possuem uma gestão relativa, com dificuldades para a proposição de medidas eficazes e pró-ativas para a gestão e gerenciamento dos RCC, além disso, observou-se a falta de informações junto as Prefeituras Municipais em relação aos dados de geração, destinação e fiscalização dos RCC. A partir do diagnóstico evidenciou-se a necessidade de maior atenção por parte dos municípios no âmbito da gestão e do gerenciamento dos RCC.
GERENCIAMENTO DE RISCO NO LICENCIAMENTO AMBIENTAL: O CASO DO ROMPIMENTO DA BARRAGEM DE FUNDÃO
Authors: Matos Maria Eduarda Nogueira , Almeida Maria Rita Raimundo e
Published: February 2021

O dia 05 de novembro de 2015 será lembrado pela tragédia do rompimento da barragem de rejeitos de Fundão, da empresa Samarco, na cidade de Mariana/MG. Este acidente é considerado de grandes dimensões e dos mais graves desastres socioambientais do Brasil. Diante da sua importância, o presente estudo teve como objetivo avaliar o processo de licenciamento ambiental da barragem de Fundão da mineradora Samarco, que foi rompida, com a finalidade de identificar como o risco de rompimento da barragem foi gerenciado. O estudo foi realizado a partir da análise de conteúdo dos documentos componentes de processos de licenciamento. A partir dos dados levantados, foi possível observar que os impactos de um possível rompimento da barragem foram subestimados, tanto pela empresa como pelos órgãos ambientais do Estado, uma vez que a empresa não considerou tal possibilidade de forma significativa e os órgãos ambientais não foram atentos a essa situação, evidenciando uma grave falha no processo de gerenciamento de risco do empreendimento. Diante da importância econômica da indústria mineradora para a economia do Brasil e tendo em vista os inúmeros impactos ambientais inerentes a esta atividade, é necessário que o processo de licenciamento ofereça segurança e garantia de uma gestão de riscos responsável e capaz de dimensionar seu impacto potencial na tentativa de se evitar novas tragédias.
Dental developmental anomalies and post-eruption dental disorder
Authors: Sales de Sá Raísa , Cardoso Lais Inês Silva , Brito Jordana Almeida , Braga Alina Nunes , Lima Laise Nascimento Correia , Lawall-Silva Melaine Mont’Alverne , Pereira Erika Martins
Published: February 2021

Panoramic radiographs are complementary exams to evaluate oral alterations in an early manner, these changes can be dental developmental anomalies, and post-eruption dental disorder. Aim: This study evaluated the findings in panoramic radiographs and correlated the variables of gender and dental location. Methods: A retrospective study was through the observation of 1.111 panoramic radiographs from the Radiology Department in Brazil. It was included patients from 5 to 79 years of age of both gender, and it classified the anomalies in shape, size, and number and post-eruption dental changes in and correlated with gender and location. Patients with syndromes were excluded from the sample. Results: The majority of the sample was composed of fameles 752 (67.7%), as to the frequency of dental developmental anomalies related lesions 684 cases (61.6%) and post-eruption dental disorder 567 (51.8%), in the radiographs. The most prevalent change was endodontic treatment (32.6%), followed by root dilaceration (25.9%), and included tooth (19.5%). The most prevailing alteration when correlated with the gender variables was the cyst root (p<0.01) in females, and orthodontic treatment (p=0.02) in males and the variable location in the mandible was root dilaceration, giroversion, impacted tooth, taurodontia, microdontia, and endodontic treatment (p<0.01). Conclusion: Our findings provide evidence that dental developmental anomalies e post-eruption dental disorder are frequent alterations in the population with particular characteristics of distribution by sex and location.
Surface treatment and adhesion approaches on polymer-infiltrated ceramic network
Authors: May Michele Mirian , Rodrigues Camila da Silva , Da Rosa Juliane Bortolotto , Herrmann Júlia Persio , May Liliana Gressler
Published: February 2021

Aim: To evaluate the effect of different surface treatments and adhesive approaches on the microshear bond strength of resin cement to a polymer-infiltrated ceramic network (PICN). Methods: PICN blocks were randomly assigned into 9 groups (n=10): CTRL: no treatment; HF: 5% hydrofluoric acid etching; HF-S: HF + silane; HF-S-A: HF-S + adhesive (Adper Single Bond 2); HF-UA: HF + universal adhesive (Single Bond Universal); SB: sandblasting with 50 μm Al2O3 particles; SB-S: SB + silane; SB-S-A: SB-S + adhesive; SB-UA: SB + universal adhesive. Resin cement microcylinders (Ø = 0.96 mm; height = 1 mm) (RelyX Ultimate) were built upon the PICN surface after roughness and contact angle measurements. Next, microshear bonding tests (μSBS) were performed (0.5 mm/min) after water storage (37ºC, 90 days) and thermocycling (12,000 cycles; 5ºC-55ºC). Failure modes were observed under stereomicroscope. Bond strength data were analyzed by two-way ANOVA/Tukey’s test and t-tests. Kruskal-Wallis/Dunn’s tests were conducted for roughness and contact angle data (α = 0.05). Results: A rougher surface and lower contact angles were observed for Sandblasting. HF-S (18.54 ± 2.03 MPa), SB-S (19.00 ± 1.66 MPa) and SB-UA (18.07 ± 2.36 MPa) provided the highest bond strength values, followed by the other treated groups. The CTRL group resulted in lower bond strength (7.18 ± 2.34 MPa). Conclusion: Hydrofluoric acid etching followed by silane application and sandblasting followed by silane or universal adhesive are useful clinical steps to enhance bonding to PICN. Adhesive applications after HF etching have no advantages in bonding to PICN.
Analysis of Risk Factors Affecting The Occurrence of Chronic Obstructive Pulmonary Disease in Indonesia
Authors: Firdausi Nurul Layly , Artanti Kurnia Dwi , Li Chung-Yi
Published: February 2021

Background: Chronic obstructive pulmonary disease (COPD) is a lung disease caused by the occurrence of airflow limitation in the lungs and also causes 60% of all deaths in Indonesia. Purpose: This study aimed to analyze the risk factors that affect the incidence of COPD in Indonesia. Methods: This study was conducted in July–August 2019 in Indonesia as an analytic research study with a cross-sectional design, using data from the Indonesia Family Life Survey-5. The sample consisted of respondents aged >15 years, giving a total of 34,231 respondents. Data analysis was partially carried out using the chi-square test to analyze the relationships between the variables. Results: The majority of respondents were female, were aged <40 years, and had a low level of education. Risk factors for the development of COPD included, among others, an age of >40 years (p = 0.02; PR = 1.20; 95% CI = 1.02–1.41), male gender (p = 0.01; PR = 1.26; 95% CI = 1.07–1.49), smoking (p = 0.01; PR = 1.22 ; 95% CI = 1.03–1.44), first smoking age < 40 years (p = 0.02; PR = 1.22; 95% CI = 1.03–1.44), residence in urban areas (p = 0.01; PR = 1.43; 95% CI = 1.20–1.70), being underweight (p = 0.01; PR = 2.17; 95% CI = 1.76–2.66). Conclusions: The risk factors that affect the incidence of COPD include being aged >40 years, being male, smoking, taking up smoking when aged <40 years, urban residence, and being underweight.
The Implementation of Immunization Cold Chain Management in Surabaya City
Authors: Lusita Alfilia , Syahrul Fariani , Ponconugroho Ponconugroho
Published: February 2021

Background: Immunization success rates can be determined by several factors. The factors that can cause occurrences of immunization preventable disease (PD3I) cases include the quality of the cold chain and invalid doses of immunization medicines. Purpose: The aim of this research was to analyze the implementation of cold chain management in the city of Surabaya. Methods: This research was conducted as a descriptive study with a cross-sectional research design. The population consisted of all primary health care centers in the city of Surabaya, and the data used were secondary data, guided by interviews with informants. Results: The majority of cold chain management personnel were found to have a medical education background of 98.42%, and primary health care workers have received cold chain-related training (100%). All primary health care equipment has a 100% cold chain. The completeness of cold chain reporting was 93.51%, and the accuracy of the cold chain reporting was 71.52%. Regarding the quality of the equipment, some vaccine refrigerators were found 12% of vaccine refrigerators were found not to be in optimal condition, and 14% of temperature monitoring devices was not activated. Conclusion: The implementation of cold chain management in public health center and the availability of equipment in the Surabaya City are going well, although there are still some problems such as undisciplined reporting and inadequate quality of tools for cold chain implementation as well as the discovery of vaccine refrigerators easily leaks, and their temperature can rise easily.
Profile of Psoriasis Vulgaris Patients Treated with Methotrexate at Dr. Soetomo Hospital, Surabaya, 2017–2018
Authors: Damayanti Damayanti , Pratiwi Karina Dyahtantri , Nugroho Wisnu Triadi
Published: February 2021

Background: Psoriasis Vulgaris is a chronic inflammatory skin disease that affects patients’ quality of life. Methotrexate is the first-line and most effective systemic therapy in psoriasis vulgaris management. Purpose: The aim of this study was to evaluate clinical improvement after methotrexate therapy and any adverse effects of methotrexate therapy in psoriasis vulgaris management. Methods: The data for this descriptive, retrospective study were retrieved from the medical records of 22 psoriasis vulgaris patients who were treated with methotrexate therapy between January 2017 and June 2018 in the Child Kemuning Ward (IRNA), Dr. Soetomo General Hospital in Surabaya, East Java. Results: Data for a total of 22 subjects were collected for this study. The majority of the subjects were in the age group 25–59, and the average age was 40.50±17.20. Good clinical improvement (decrease in the body surface area of the lesion) was found in all patients. The adverse effects of methotrexate were evaluated based on the elevation of liver and renal function test levels. An elevation of aspartate aminotransferase levels was found in 11 patients, and an elevation in alanine aminotransferase levels was found in 13 patients. Elevated blood urea nitrogen levels were found in eight patients, and elevated serum creatinine levels were found in four patients. Conclusion: Methotrexate is an effective treatment for severe psoriasis vulgaris management when administered with careful selection and regular monitoring of patients. Application of methotrexate therapy in accordance with the guidelines remains suitable for psoriasis vulgaris management with vigilance regarding methotrexate’s adverse effects.
Spatial Analysis of Dengue Hemorrhagic Fever based on Influencing Factors in Jombang, 2014–2018
Authors: Hastuti Retno Tri , Hendrati Lucia Yovita
Published: February 2021

Background: Jombang District is an endemic area of dengue hemorrhagic fever (DHF). Purpose: The aim of this study was to spatially analyze various factors simultaneously (multivariate analysis) in relation to the incidence of DHF in Jombang District during the period 2014–2018. The factors studied were population density, larvae free index, rainfall, coverage of healthy homes, and healthy lifestyle coverage. Methods: The research was conducted as an observational study with an ecology research design. The data were secondary data from the Health Office and Statistic Central Bureau of Jombang District. The population consisted of 21 sub-districts in Jombang District in 2014–2018. The sample used the total population. The data analysis tool used in this study was GeoDa regression Moran's I software. Results: The bivariate analysis showed that there was a correlation between larvae free index (p = 0.04), healthy lifestyle coverage (p = 0.02), rainfall intensity (p = 0.20), population density (p = 0.07), and coverage of healthy houses (p = 0.22) with DHF incidence. According to Moran's I for spatial dependence (multivariate analysis), showed that there was a correlation between all the variables and DHF (p = 0.03). Conclusions: The variables of larvae free index and healthy lifestyle coverage related to the Incidence Rate (IR) of DHF cases. There was no correlation between IR and variable population density, rainfall, or coverage of healthy homes. Various spatial factors are simultaneously related to IR, even though only two variables are shown to be related to IR in the bivariate analysis.
PELATIHAN PENGGUNAAN MMICROSOFT OFFICE BAGI GURU SMP AL-HAMIDIYAH PALEMBANG
Authors:   Fakultas Teknik, Universitas Muhammadiyah Palembang, Rosyidah Masayu , Marhaini Marhaini , Sary Reny Kartika , Ardianto Febi , Apriani Yosi
Published: February 2021

The teacher is a professional educator with the task of educating, teaching, guiding, directing, training, assessing, and evaluating students in early and secondary education in certain formal institutions. One of the problems faced by Al-Hamidiyah Middle School teachers is the low competency of teachers, especially in the use of computer technology devices. This is unfortunate, even though the demands on teachers' assignments are in line with the enactment of the 2013 curriculum, where teachers are required to work using applications, learning media using information technology, application-based assessment systems, computer-based national exams, and others. This obstacle occurs because there is still a lack of teacher motivation to add competence outside the main task for a variety of reasons conveyed. The approach used in this dedication activity with a persuasive-educative approach, by providing knowledge, understanding, and skills in using Microsoft Office. The method used in the form of lectures, practice, and discussion. The results of this dedication the teacher understands and is able to practice directly.
PELATIHAN PETUGAS PANTI DAN PEMBERIAN TAK (TERAPI AKTIFITAS KELOMPOK) TERTAWA PADA LANSIA DI PANTI HARAPAN KITA OGAN ILIR
Authors:   Fakultas Kedokteran, Universitas Sriwijaya, Jaji Jaji , Natosba Jum , Fikri M Zainal
Published: February 2021

The aging process results in a person experiencing a decrease in physiological function so that many non-communicable diseases appear in the elderly. Besides degenerative problems reduce endurance so it is susceptible to infectious diseases. Among the various health problems in the elderly that become chronic conditions are joint disease / rheumatism, hypertension, and followed by other diseases. The purpose of community service activities among others, the elderly can demonstrate nonpharmacological therapy to control joint pain. The method of activities includes providing therapy for group laughter activities to the elderly and training the orphanage staff about giving no laughter, which are supporting activities of the orphanage in order to improve the health of the orphans as optimal as possible. The target audience in this service activity is a group of 7 orphanage officers, and as many as 35 elderly people. Laughing for 5-10 minutes can stimulate endorphin and serotonin expenditure, which is a type of body's natural morphine and melatonin. These three substances are good substances for the brain so we can feel calmer. We hope that the elderly who are in our homes should always follow the activities carried out by the management of the orphanage, because all activities will have a positive influence on the elderly in the orphanage, and for the homes of our hopes, hopefully the training provided can be applied to the elderly for at least a month. once, and scheduled.
OPTIMALISASI PELAYANAN APOTIK PANJEN DI DESA WEDOMARTANI NGEMPLAK SLEMAN YOGYAKARTA
Authors:   FMIPA Universitas Islam Indonesia, Chabib Lutfi , Fauzy Akhmad
Published: February 2021

Community service activities have been completed to optimize Panjen Pharmacy services. Pharmaceutical services are integrated activities aimed to identify, prevent, and resolve drug problems and health-related problems. The demands of patients and society for improving the quality of pharmaceutical services require the expansion of the old drugs-oriented paradigm into a new patient-oriented paradigm with the philosophy of Pharmaceutical Care. The Panjen Pharmacy in Wedomartani Village, Sleman is still constrained in implementing pharmaceutical services. Based on the results of observations to partners, these problems resulted from A limited number of human resources, lack of facilities and infrastructure, the absence of standardized etiquette, no drug information handbook, and there is no counseling card. The average number of visits by patients who buy drugs at the Panjen Pharmacy per day reaches 35-70 people. So it is necessary to improve services to provide a sense of security to patients about the use of drugs to be consumed. The outcome of this service activity is to optimize Panjen Pharmacy services through increasing human resource capacity, improving infrastructure, availability of standard etiquette, counseling cards, and drug information book achieved with the Participatory Rural Appraisal (PRA) participatory community empowerment model. The continuity of this service activity is the achievement of consistency in the application of a good and correct rationing system, both in terms of Human Resources Utilization (Human Resources), as well as in terms of a management information system that can guarantee the availability of the right type of drug, the right amount, the right quality and the right time. , thus making the pharmacy better in terms of service to the community and healthier.
PHOTOCATALYTIC SOLAR OXIDATION OF ACESULFAME-K. EFFECT OF INITIAL pH, CATALYST DOSE AND OXIDANT CONCENTRATION
Authors: Morales Mejía Julio César , Anselmo Cervantes Karla Ibette , García Mendoza Iván , Almanza Rafael
Published: February 2021

Aqueous acesulfame-K was oxidized in a pilot solar photocatalytic reactor, equipped with a compound parabolic collector (CPC). The reactor has an area of 0.40 m2 of CPC collectors with geometrical concentration ratio of 1 and a simple mechanical configuration. The experiments of photocatalytic oxidation of acesulfame-K were performed by treating 2 L of water with an initial concentration of 15 mg/L. The photocatalyst used was P25 (Aeroxide TiO2) from Evonik. One of the goals of the research work was to find a set of conditions to efficiently remove this emerging concern pollutant. Results allowed proposing a set of reaction conditions that lead to a high removal of acesulfame-K. In addition, the experimental design allowed determining the effect of initial pH as well as the impact of initial concentrations of photocatalyst and chemical oxidant. The removal efficiency of acesulfame-K and related UV-absorbing species reached values up to 96-99 % and there was not a quantifiable amount of intermediate products (analyzed as UV absorbing species). Despite reaction time was fixed in 3 h for all the experiments, oxidation efficiencies higher than 95 % were reached at 2 h of reaction or even before.
Order-Stability in Complex Biosystems from the Viewpoint of the Theory of Open Quantum Systems
Authors: Khrennikov Andrei , Watanabe Noboru
Published: February 2021

This paper is our attempt on the basis of physical theory to bring more clarification on the question ``What is life?'' formulated in the well-known book of Schr\"odinger in 1944. According to Schr\"odinger, the main distinguishing feature of biosystem's functioning is the ability to preserve its order structure or, in the mathematical terms, to prevent increasing of entropy. Since any biosystem is fundamentally open, it is natural to use open system's theory. However, Schr\"odinger's analysis shows that the classical theory is not able to adequately describe the order-stability in a biosystem. Schr\"odinger should also appeal to the ambiguous notion of negative entropy. We suggest to apply the quantum theory. As is well-known, behaviour of the quantum von Neumann entropy crucially differs from behaviour of the classical entropy. We consider a complex biosystem $S$ composed of many subsystems, say proteins, or cells, or neural networks in the brain, i.e., $S=(S_i).$ We study the following problem: if the composed system $S$ can preserve the ``global order'' in the situation of increase of local disorder and if $S$ can preserve its entropy while some of $S_i$ increase their entropies We show that within quantum information theory the answer is positive. The significant role plays entanglement of the subsystems states. In the absence of entanglement, increasing of local disorder generates disorder increasing in the compound system $S$ (as in the classical regime).
Curvature Properties of Almost Ricci-Like Solitons with Torse-Forming Vertical Potential on Almost Contact B-Metric Manifolds
Authors: MANEV MANCHO
Published: February 2021

A generalization of $\eta$-Ricci solitons is considered involving an additional metric and functions as soliton coefficients. The soliton potential is torse-forming and orthogonal to the contact distribution of the almost contact B-metric manifold. Then such a manifold can also be considered as an almost Einstein-like manifold, a generalization of an $\eta$-Einstein manifold with respect to both B-metrics and functions as coefficients. Necessary and sufficient conditions are found for a number of properties of the curvature tensor and its Ricci tensor of the studied manifolds. Finally, an explicit example of an arbitrary dimension is given and some of the results are illustrated.
Combined Aortic Valve Replacement and Coronary Bypass Grafting in Patient With Lipton’s R-III Type of Single Coronary Artery Anomaly
Authors: Kocica Milica Karadzic , Ugrinovic Hristina , Lazovic Dejan , Karamarkovic Nemanja , Grujic Milos , Lukic Borivoje , Radmili Oliver , Cvetic Vladimir , Kocica Mladen
Published: February 2021

A single coronary artery is a very rare condition, commonly associated with other congenital anomalies. It could be generally classified as neither benign nor malignant form of congenital coronary artery anomalies since its pathophysiological and clinical implications grossly depend on different anatomical patterns defined by the site of origin and distribution of the branches. By presenting the patient with an isolated single coronary artery, who underwent successful combined aortic valve replacement and coronary artery bypass grafting surgery, we intend to distinguish casual from causal in this extremely rare clinical and surgical scenario. This is the first-ever case published, combining such underlying pathology, clinical presentation, and surgical treatment.
Challenges Faced by UK University Students Due to the Coronavirus Crisis in the Higher Education
Authors: Kulkarni Siddharth Suhas , Chima Parmjit
Published: February 2021

The COVID-19 pandemic is one of the worst catastrophes that we have faced globally in recent years. It has not only taken its toll on the economic sector but also on the education sector. The social distancing norms that are in place as a direct response to the pandemic have turned conventional classroom teaching into a problematic minefield; as such, students all over the world have been forced into unprecedented situations that have served only to worsen the situation. The current pandemic has given rise to one of the worst crises the 21st Century has ever seen, resulting in a surge of unemployment. Many companies have taken the route of firing employees or making redundancies, as they cannot afford the monthly reimbursement for staff. While this issue primarily concerns full-time workers, it also carries significant consequences for students – a considerable number of students are required to earn their daily living costs, and, without a job, they cannot pay their educational fees, accommodation costs, or living expenses. This comprehensive study briefly discusses the multitude of problems faced by students in the UK regarding higher education, as a direct result of the coronavirus pandemic. It contains six individual sections: a detailed introduction; the methodological procedures employed; educational disruptions, covering issues from hindrances in field research to examinations and student evaluations; personal problems experienced by students, such as accommodation and loss of income; concerns arising from the global pandemic; and finally, a conclusion and summary of the study’s findings.
The Importance of Music Education in the Development and Performance of Executive Functions
Authors: Domínguez Villamizar Carlos Andrés
Published: February 2021

In recent years, music education in Ibero-America has been losing ground within the school environment in favor of the development of curricular systems that benefit academic results in standardized tests. Despite this, several studies in the field of cognitive neurosciences have found evidence of great relevance and in which it can be observed how music education can favor cognitive development and performance in practically all stages of human development, with important results in language tasks, attention, and executive functions such as planning, inhibition, cognitive flexibility and working memory.
Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge
Authors: Maurya Vaibhav , Shakya Amita , Aggarwal Manjeet , Gothandam K.M. , Bohn Torsten , Pareek Sunil
Published: February 2021

Accruing evidence on the influence of β-carotene regarding the prevention of several chronic diseases - in addition to its well-acknowledged role in vision has been a strong driver for developing alternative delivery systems. Though oral delivery is accepted as the most fitting, mild and safe path for delivering bioactive agents, β-carotene delivery via food items poses challenges due to its lipophilic nature, poor water-solubility, high chemical/photochemical instability and poor oral bioavailability. Nanotechnology has opened new windows for delivering bioactive agents. Their physiochemical characteristics, i.e. small size, high surface area, unique composition, biocompatibility and biodegradability make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers inherit some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has been rapidly evolved, with a plethora of innovative nano-engineered materials, including micelles, nano/microemulsion, liposomes, niosomes, solid-lipid nanoparticles and nanostructured lipid carriers. These nano-delivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nano-delivery systems adopted for developing functional foods: depicting their classification, composition, preparation methods, challenges, release-and absorption of β-carotene in the GIT and possible risks and future prospects.
Mechanics of the Gyroscopic Precession and Calculation of the Galactic Mass
Authors: Sun Jian , Xu Tin , Jiao Zheng , Wang Hui
Published: February 2021

A spinning gyroscope precesses about the vertical due to a torque acting upon the wheel. The torque is generated by the shift of moment of force by gravity and it points to the vertical instead of the tangential direction of precession. This intuition offers an alternative and straightforward view of precession dynamics in comparison with the literature. It also presumes a dynamic balance of momentum between circular motions of the wheel spin and precession. Accordingly, the gyroscopic dynamics is then applied to the study of galactic motion of the solar system in space and the Galactic mass is calculated with the inclusion of gyroscopic effect of the solar planets. Results indicate that the gyroscopic effect of Mercury orbiting around the Sun can increase the calculated Galactic mass by 23% in comparison with the result obtained by the classic approach.
Principal Component Analysis of RNA-seq Data Unveils a Novel Prostate Cancer-Associated Gene Expression Signature
Authors: Perera Yasser , Gonzalez Augusto , Perez Rolando
Published: February 2021

Prostate cancer (Pca) is a highly heterogeneous disease and the second more common tumor in males. Molecular and genetic profiles have been used to identify subtypes and guide therapeutic intervention. However, roughly 26% of primary Pca are driven by unknown molecular lesions. We use Principal Component Analysis (PCA) and custom RNAseq-data normalization to identify a gene expression signature which segregates primary PRAD from normal tissues. This Core-Expression Signature (PRAD-CES) includes 33 genes and accounts for 39% of data complexity along the PC1-cancer axis. The PRAD-CES is populated by protein-coding (AMACR, TP63, HPN) and RNA-genes (PCA3, ARLN1) sparsely found in previous studies, validated/predicted biomarkers (HOXC6, TDRD1, DLX1), and/or cancer drivers (PCA3, ARLN1, PCAT-14). Of note, the PRAD-CES also comprises six over-expressed LncRNAs without previous Pca association, four of them potentially modulating driver’s genes TMPRSS2, PRUNE2 and AMACR. Overall, our PCA capture 57% of data complexity within PC1-3. GO enrichment and correlation analysis involving major clinical features (i.e., Gleason Score, AR Score, TMPRSS2-ERG fusion and Tumor Cellularity) suggest that PC2 and PC3 gene signatures might describe more aggressive and inflammation-prone transitional forms of PRAD. Of note, surfaced genes may entail novel prognostic biomarkers and molecular alterations to intervene. Particularly, our work uncovered RNA genes with appealing implications on Pca biology and progression.
Pengaruh Penerapan Model Blended-Problem Based Learning terhadap Kemampuan Berpikir Kritis Pesrta Didik pada Materi Asam dan Basa
Authors: Darwis Darsef , Rahman Arif , Latif Maulana
Published: February 2021

Penelitian ini bertujuan untuk mengetahui pengaruh penerapan model pembelajaran Blended-Problem Based Learning terhadap kemampuan berpikir kritis peserta didik pada materi Asam dan Basa. Kuasi eksperimen dipilih sebagai metode penelitian dengan desain posttest only group. Populasi dalam penelitian merupakan peserta didik kelas XI IPA 1 dan XI IPA 2 SMA Negeri 26 Jakarta. Penentuan sampel menggunakan teknik purposive sampling, dengan memilih dua kelas yang dijadikan sebagai kelas eksperimen dan kelas kontrol. Kelas eksperimen diterapkan pembelajaran menggunakan model Blended-Problem Based Learning, sedangkan kelas kontrol diterapkan pembelajaran menggunakan model Blended-Explicit Instruction. Pengumpulan data menggunakan tes soal kemampuan berpikir kritis materi asam dan basa. Data dianalisis menggunakan statistik uji t sampel independen. Hasil penelitian menunjukkan bahwa nilai rata-rata posttest kelas eksperimen sebesar 68,306 dan kelas kontrol sebesar 58,611. Hasil pengujian terhadap hipotesis diperoleh dengan nilai thitung (3,454) > ttabel (1,667) pada taraf signifikan 0,05. Dengan demikian, dapat disimpulkan bahwa terdapat pengaruh positif pada penerapan model pembelajaran Blended-Problem Based Learning terhadap kemampuan berpikir kritis peserta didik pada materi Asam dan Basa.
ESCOLAS DO SÉCULO 21: APRENDIZAGEM DE HISTÓRIA BASEADA EM PROJETOS NO IFC - CÂMPUS CAMBORIÚ. CENTURY 21 SCHOOLS: LEARNING OF HISTORY BASED ON PROJECTS IN IFC - CÂMPUS CAMBORIÚ.
Authors: Maria Eduarda Gomes CARDOZO  , Eduarda Brenda de FREITAS  , Ivan Carlos SERPA
Published: February 2021

A presente pesquisa investigou a aplicação de novas metodologias de ensino de Históriajunto aos primeiros anos dos cursos técnicos integrados ao nível médio do Instituto FederalCatarinense – Câmpus Camboriú, Santa Catarina, Brasil, entre agosto de 2017 e maio de2018. A metodologia adotada referenciou-se na “aprendizagem baseada em projetos”, cujofoco são as motivações e necessidades dos alunos, a integração entre ensino e pesquisa e abusca de alternativas viáveis à rotina monótona das salas de aula (CALVO, 2016). Duasexperiências de ensino foram investigadas nesta pesquisa: o teatro histórico e osambaqui/escola, sendo esta última uma produção original surgida deste trabalho depesquisa. Os resultados obtidos demonstram que as metodologias ora investigadas tornam aaprendizagem de História prazerosa, inspiradora e transformadora da realidade social dosjovens.
ALTERNATIVAS AO USO DE ANTIBIÓTICOS VIA RAÇÃO NA PRODUÇÃO DE SUÍNOS
Authors: Pietra Viertel Molinari  , Marcelo Felipe Güths  , Helloá Alaide Siqueira  , Julia Helena Montes  , Maiko Giorgi Philippe  , Vanessa Peripolli  , Fabiana Moreira  , Yuso Henrique Tutida  , Cleverson Hebbel  , Renato Irgang  , Jalusa Deon Kich  , Ivan Bianchi
Published: February 2021

Em decorrência do crescimento da demanda por proteína animal nos últimos anos, o uso de antimicrobianos na suinocultura aumentou, com o intuito de tratar e prevenir doenças. Entretanto, o uso irregular desses princípios contribui para o surgimento de cepas bacterianas resistentes e para o aparecimento de resíduos de medicamentos na carne suína, sendo um grande problema à saúde pública. Nessa circunstância, muitas são as pesquisas que buscam alternativos que possibilitem a manutenção da saúde dos animais sem que o desempenho seja comprometido. Portanto, alguns aditivos podem ser alternativas ao uso de antibióticos, entre eles estão os prebióticos, probióticos, ácidos orgânicos e óleos essenciais. O objetivo do trabalho foi avaliar o impacto da substituição de antibióticos utilizados na ração de suínos com aditivos alternativos na fase de creche, crescimento e terminação. Inicialmente o experimento utilizou 1091 animais desmamados divididos em 36 baias com seis tratamentos durante a fase de creche e na fase de crescimento e terminação restaram 840 animais. Ao desmame os animais foram divididos por sexo (fêmeas e machos), submetidos ao protocolo vacinal e pesados individualmente para realizar a distribuição homogênea entre os seis tratamentos, sendo: T1: ração sem antibiótico, T2: ração com antibiótico, T3: ração com prebiótico, T4: ração com probiótico, T5: ração com óleo essencial, T6: ração com ácido orgânico. Na saída de creche foi realizada a segunda pesagem do animais para determinar a conversão alimentar. Também foram coletados os dados de mortalidade. Não foi observada diferença na conversão alimentar entre os tratamentos na creche (P=0,2222), nem no crescimento e terminação (P=0,8098). O percentual de morte não diferiu entre os tratamentos na fase de creche (P=0,5413), enquanto no crescimento e terminação a mortalidade foi maior (P=0,0197) nos tratamentos livre de antibiótico e ácido orgânico. A substituição do uso profilático de antimicrobianos via ração na produção de suínos é uma opção possível para garantir a segurança alimentar e diminuir a geração de resíduos visto que o uso de alternativos não impactou no desempenho dos animais.