bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of using WhatsApp in online learning setting on Indonesian EFL students’ writing apprehension and the relation with their writing achievement
Authors:   Universitas Lampung, Habibah Arum , Nurweni Ari ,   Universitas Lampung, Deviyanti Rafista ,   Universitas Lampung
Published: March 2022

The primary goals of this research are to investigate the students’ writing apprehension level after being taught through WhatsApp in online learning setting and to find out the correlation between writing apprehension and writing achievement. This study was carried out quantitatively and involved one class of grade X which consisted of thirty-five students. The data was collected through English Writing Test and Writing Apprehension Test, a questionnaire that was developed by Daly and Miller (1975). To test the hypotheses, paired sample t-test and Pearson correlation analysis were applied. The finding of paired sample t-test revealed that there was a significant reduction in the students’ writing apprehension level after the implementation of WhatsApp in online writing classes. Meanwhile, for the correlational analysis, it was done three times to obtain more specific results; the correlation of the data before the treatment, the correlation of the data after the treatment, and the correlation of gain scores of the data. The results showed respectively that two correlational analyses had very high correlation and the last one had an average correlation. Furthermore, all findings showed significant negative correlation; meaning that there was a significant inverse relationship between writing apprehension and writing achievement. This implied that the lower the level of writing apprehension is, the higher the score of writing achievement would be. In conclusion, the implementation of WhatsApp in online writing class is effective to improve students' writing achievement and effective to reduce students’ writing apprehension in Indonesian EFL students.
The teacher’s questioning strategies and the students’ responses in the classroom interactions at the first year of SMAN 2 Bandarlampung
Authors:   Universitas Lampung, Hasanah Uswatun , Sukirlan Muhammad ,   Universitas Lampung, Mahpul Mahpul ,   Universitas Lampung
Published: March 2022

The current research was conducted to investigate: (1) the questioning strategies used by the teacher in classroom interaction, (2) the students’ responses of the questioning strategies in classroom interaction. The subjects of the study were an English teacher and 30 first year senior high school students at Bandar Lampung. This study was conducted qualitatively by using case study method. The data were collected through classroom observation and interview with students. The observation was used to collect the data of the teacher’s questioning strategies. The interview was conducted to elicit the students’ responses of the teacher’s question. The results showed that the teacher used five teacher’s questioning strategies in the classroom interactions, i.e., repetition, decomposition, rephrasing, code-switching, and wait-time. Wait time strategies were the most frequently used by the teacher. The students were found to have responded the teacher’s questions in forms of both relevant (77%) and irrelevant (23%). This suggests that the teacher’s questions were effectively addressed by the majority of the students. Keywords: classroom interaction, teacher’s questioning strategies, students’ responses.
The implementation of the talking chips technique to improve students’ speaking ability at the second grade students of SMAN 1 Seputih Agung
Authors:   Universitas Lampung, Pranoto Erwin , Yufrizal Hery ,   Universitas Lampung, Supriyadi Deddy ,   Universitas Lampung
Published: March 2022

The objectives of this research were to find out i) whether there was statistically significant improvement of the students’ speaking ability after the students were taught through the Talking Chips technique and ii) the students’ perceptions of the implementation of the technique. One group pretest posttest was used as the design of the study. The subjects of the research were 34 students of XI MIA I of SMAN 1 Seputih Agung in academic year 2019/2020. The instruments were the speaking test and interview protocol. The data were in the form of speaking scores taken from the pretest, the posttest and interview. The results showed that there was statistically significant improvement of students’ speaking ability in terms of pronunciation, vocabulary, grammar, fluency, and comprehension with the significant level <0.05. Furthermore, the result of the interview showed that the majority of the students (96%) had positive perceptions of the technique. That is, the technique was perceived as the technique that gave a positive learning atmosphere that actively involved the students in the teaching and learning activities. This suggests that the Talking Chips technique facilitates the students to improve their speaking ability.
Integrating Online Corpus and Online Dictionary to Expand Student's English Vocabulary for Tourism
Authors: Fauzi Andi Rizki , Suradi S
Published: March 2022

This study was aimed to know the contribution of online corpus integrated with an online dictionary to take part in learning English vocabulary for tourism. An experimental research was conducted toward the fourth semester of Diploma III students at STIPARY Tourism Academy majoring in Hospitality. The population consists of 118 students and they were divided into 4 classes in which class A and B were randomly chosen as the samples. 100 words from the corpus created from articles in the tourism field were listed through the corpus data and the level of familiarity rated by the students. Based on the analysis result, it could be seen that Asymp. Sig (2-tailed) value was 0,000, which was less than the probability value of 0,05. It means that integrating online corpus and online dictionary could be significantly expand the students' English Vocabulary for tourism.
The Correlation between Students Reading Habit and Their Writing Ability of Narrative Text
Authors: Ihsan Muhammad Taufik
Published: March 2022

The researcher’s conducted a research at State Islamic Senior High School 1 Pekanbaru. The formulation the problems are : How is the students reading habit? How is the students’ ability of writing narrative text? Is there any significant correlation between students reading habit and their ability in writing narrative text? The design of this reseach study was correlational research. The total number of population was 262 students. The researcher used purposive sampling by taking only one class as sample 34. To analyze the data, the researcher used questionnaire and written test. Questionnaire is used to collect the data about students reading habit. The written test of narrative text was intended to find out students writing ability of narrative text. Based on data analysis, the writer found that the average score of the students’ questionnaire for students reading habit is 60.1. it is categorized into good level. students writing ability is 72.4, the score is categorized good level. the correlation between students  reading habit and their ability of writing applied to the sample is 0.629, and consulting to the critical values of the r Product Moment with 95% confidence level and the number of subjects 34 was 0.339. Therefore, the writer concludes that there is a significant positive correlation between students reading habit (X) and their ability of writing narrative text (Y).
An Experimental Study: Cartoon Videos as Media Instruction on Students Speaking Ability
Authors: Siswandi S , Rizaldi Firman
Published: March 2022

The main focus of this research is to investigate whether there was a significant difference in the speaking ability between the tenth grade students of SMA N 1 Kampar Timur. This research was classified as a quasi-experimental study. It involved 65 students of two groups, Class X MIPA 5 as the experimental group and Class X MIPA 6 as the control group. The experimental group was taught by using cartoon videos, whereas the control group was taught by using the textbook-based technique. The data were obtained by using a pre-test and a post-test. The pre-test was given to both groups before the treatment and the post-test was given after the treatment. The data of the pre-test and post-test of both groups were analyzed by using descriptive and inferential statistics. The data were calculated by using a computer program, SPSS 25 for Windows. After the data were tested and found to be homogeneous and normal, the hypothesis was tested using the Kolmogrov-Smirnov test. The results of the research show that there was a significant difference in the speaking ability between the students who were taught by using cartoon video and those who were taught by using the textbook-based technique. The significance value calculated 0.019 is bigger than 0.05 (sig value=0.109>0.05). Therefore, the hypothesis of this study is rejected.  It  means that  there is  no  significant difference on  students speaking ability who are taught by cartoon video as instructional media   at the eleventh grade of senior high school 1 Kampar Timur.
Persepsi Masyarakat Terhadap Pemberdayaan Perempuan Pada Program Pnm Mekaar Dijorong Kotobaru Air Dingin Kab. Solok
Authors: Gusmita Wiwi , Solfema Solfema
Published: March 2022

Non formal education is education that is very important to exist in the community. One form of part of education outside of school is women's empowerment which is an effort to improve the abilities and skills of women where women are always considered weak so that an empowerment is needed. There are 3 indicators in this study: 1. Financial management, 2. Timeliness 3. Borrowing rules. By using descriptive quantitative research methods. The results of this study indicate that the empowerment of women through PT PNM Mekaar can be said to have been achieved well
Hubungan Antara Perhatian Orang Tua Menurut Peserta Didik Dengan Minat Belajar Peserta Pada Pembelajaran Alquran Di TPQ
Authors: Handayani Utari , Wirdatul'aini Wirdatul'aini
Published: March 2022

This research was motivated by the low interest in learning of students in learning the Koran at TPQ Mushola Nurul Ikhlas Bukik Kaciak Kampung Benteng Nagari Duku. The low interest in learning is thought to be caused by the low attention of parents according to students. The research aims to describe students' interest in learning, describe parental attention according to students, and see the relationship between parental attention according to students and participants' learning interest in learning the Koran at TPQ at Nurul Ikhlas Bukik Kaciak Mosque. This type of research is quantitative research with correlational type. The population in this study were TPQ participants in learning the Koran and the sample was taken by random sampling technique. Data collection techniques in the form of closed interviews and data collection tools in the form of questionnaires.The data analysis technique used the percentage formula and Spearman rho correlation. The results showed that parental attention according to students was categorized as low, students' interest in learning the Koran at TPQ Mushola Nurul Ikhlas Bukik Kaciak was categorized as low, and there was a significant relationship between parental attention according to students and students' interest in learning the Koran. at the TPQ at the Nurul Ikhlas Bukik Kaciak Mosque, Kampung Benteng Nagari Duku, Koto XI Tarusan District, Pesisir Selatan Regency. It is recommended that TPQ managers and educators at the Nurul Ikhlas Bukik Kaciak Kampung Benteng Mosque in order to increase student interest in learning, then can improve things that are deemed necessary to improve learning.
Turning of high strength, austenitic stainless steels
Authors: Rinschede Timo , Felinks Nils , Biermann Dirk , Kimm Janis , Weber Sebastian , Niederhofer Philipp , Herrera Clara , Kalveram Martin
Published: March 2022

High interstitial austenitic stainless CrMn steels are characterised by significantly increased work hardening ability and strength compared with conventional CrNi austenites, yet maintaining very high ductility and toughness. The machining of high interstitial CrMnCN steels is challenging in terms of process stability and economic efficiency. In this context, unfavourable chip forms, high thermomechanical loads and the superposition of different wear mechanisms in particular lead to challenges in turning operations. In the following article, different lubricant strategies are analysed for machining of CrMnN and CrMnCN austenitic stainless steels regarding chip form, mechanical tool loads and wear. Furthermore, the workpiece properties are considered with regard to surface roughness and microstructural changes.
ON A COMPREHENSIVE CLASS OF ANALYTIC P-VALENT FUNCTIONS ASSOCIATED WITH SHELL-LIKE CURVE AND MODIFIED SIGMOID FUNCTION
Authors: Hamzat Jamiu Olusegun , Oladipo Abiodun Tinuoye
Published: March 2022

In this paper, the authors introduce and study a new class of analytic p-valent functions and its connections with some famous subclasses of analytic and univalent functions associated with shell-like curve and modified sigmoid function in the open unit disk E= {z : z |<1}. In particular, the coefficient condition for function f(z) belonging to the class Bp (λ, β) is investigated using a succinct mathematical approach. In addition, as a special case, convex functions of order 1/4 are shown to be in the aforementioned class Bp(λ, β) in E. With the aid of subordination principle, the authors obtain the first three Taylor-Maclaurin coefficients |ap+1 | , |ap+2 | and |ap+3 | as well as the Fekete-Szegö functional |ap+2 -ηa2p+1| for functions f(z) belonging to the class Bp(λ, β, σ;p ̃) involving modified sigmoid function and associated with shell-like curve.
Las políticas exteriores feministas: más allá del discurso
Authors:   Investigadora, CIDOB, Arco Escriche Inés
Published: March 2022

Tras décadas de progresos en la promoción de los derechos de la mujer y la igualdad de género en la política internacional, un grupo reducido –pero creciente– de países ha introducido recientemente ciertas premisas del feminismo como un elemento definitorio de su política exterior. Sin embargo, estas políticas exteriores feministas, guiadas por un enfoque ético y normativo, deben hacer frente a múltiples retos que amenazan con erosionar sus objetivos transformadores. Entre ellos, un escenario internacional definido cada vez más por concepciones tradicionales de la seguridad o del interés nacional que influyen en las prioridades y decisiones de la acción exterior de los estados. Ante la brecha entre un discurso ambicioso y una implementación fragmentada y contradictoria, urge la necesidad de ir más allá de utilizar el feminismo como una simple etiqueta si estos países buscan realmente acabar con la desigualdad –en lugar de (re)producirla– y hacer frente a la creciente contestación de los derechos de las mujeres y la igualdad de género a escala global.
3D Chemometric Model Simulating the Acitheca Polymorpha Frond: Implications for Reconstructing Carboniferous Ferns (Marattiales, Canada)
Authors: D’Angelo José A. , Zodrow Erwin L. , Pšenička Josef
Published: March 2022

Reported are results of an initial approximate imitation of a Carboniferous fern frond, i.e., marattialean Acitheca polymorpha (Schimper), Middle Pennsylvanian Sydney Coalfield, Canada. The simulation experiment is based on the analysis of 14 infrared spectra obtained by means of Fourier Transform Infrared spectroscopy from four detached fragments of sterile polymorphic penultimate-pinna compressions. The calculated relative, semi-quantitative, chemical data from the infrared spectra are the input for principal component analysis deriving a 3D (three-dimensional) chemometric model. To interpret it, the four specimens are placed in hypothetical-frond positions simulating a tripinnate frond, based on diminishing penultimate-rachial widths from 1-mm (distal) to 10-mm (proximal). Hypothetical conclusions include position-dependent chemistries, specifically that of opposing trends of aromaticity vs. aliphaticity in pinnules-rachises. This, in turn, would suggest potential for (i) fern-frond reconstruction, and (ii) for determination of a most likely frond position of fragmentary specimens by “chemical classification”; the predictive aspect. However, further experimental refinement is necessary particularly based on larger frond segments to confirm or disconfirm the overall hypothetical results.
Defining National Memories: The Cases of Popular Rebellions in Ireland and Québec
Authors: Davis Christophe
Published: March 2022

While studies on nations and nationalism have brilliantly demonstrated the influence of collective memory on national development, few studies have examined the reciprocity of this relationship. This article is therefore concerned with the laborious processes of memorizing the founding myths of both the Irish and Québécois nations. Indeed, while today the rebellion of 1798 in Ireland and those of 1837–1838 in Québec are central to their respective processes of identity-building, it has not been a calm process; the 1798 rebellion was buried in collective amnesia for almost a century and in Québec, the Patriotes rebellions have constantly moved in and out of collective memory. I argue, in this article, that the unstable definition of both nations harmed the process of remembrance. I am therefore interested in the long and conflicting journey that has enabled the Irish and Québécois nations to define themselves, respectively, by their religion and their language. Through a historiographical analysis of the speeches from several leaders of these two nationalist movements, this article shows how nations define and redefine themselves and how memories are also altered to meet those changes.
The Analysis of the Strength of the Ship’s Hull After Running Aground
Authors: Kiciński Radosław , Jurczak Wojciech , Świątek Krzysztof
Published: March 2022

The article presents a simulation of a ship running aground. It introduces the analytical description, as well as the methodology of carrying out strength calculations when creating engineering tasks related to the topic. It shows the state of stresses and deformations of the hull of a modern minehunter after a collision with the bottom for two immersion depths. Research and development opportunities for future considerations are highlighted in the conclusions.
Arima Model Optimal Selection for Time Series Forecasting
Authors: Romanuke Vadim
Published: March 2022

A fast-and-flexible method of ARIMA model optimal selection is suggested for univariate time series forecasting. The method allows obtaining as-highly-accurate-as-possible forecasts automatically. It is based on effectively finding lags by the autocorrelation function of a detrended time series, where the best-fitting polynomial trend is subtracted from the time series. The forecasting quality criteria are the root-mean-square error (RMSE) and the maximum absolute error (MaxAE) allowing to register information about the average inaccuracy and worst outlier. Thus, the ARIMA model optimal selection is performed by simultaneously minimizing RMSE and Max-AE, whereupon the minimum defines the best model. Otherwise, if the minimum does not exist, a combination of minimal-RMSE and minimal-MaxAE ARIMA models is used.
Directions of Development of the Autonomous Unmanned Underwater Vehicles. A Review
Authors: Orłowski Mateusz
Published: March 2022

In the paper review of unmanned underwater vehicle (AUV) is presented. The description of main systems is depicted with focus on autonomous single vehicle as well as a swarm. As a consequence of development of AUV technology, research centers are focused on issues related to increasing the degree of their autonomy. Nowadays, mostly navigation and communication as well as high-efficient propeller systems are being developed. There are problems linking this issues. Their solutions includes development of new control laws containing algorithms to prevent collisions - for unmanned vehicles with elements of the underwater environment and for several underwater vehicles cooperating with each other in a swarm.
CYLINDRICAL SHEAR WAVES IN SOIL AROUND UNDERGROUND PIPELINES
Authors:   Institute of Mechanics and Seismic Stability of Structures named after M.T. Urazbaev, Tashkent, Uzbekistan, Khusanov B. E. , Rikhsieva B. B. ,   Institute of Mechanics and Seismic Stability of Structures named after M.T. Urazbaev, Tashkent, Uzbekistan
Published: March 2022

Рассматривается численное решение одномерной задачи о распространении цилиндрических сдвиговых волн в упругой и упругопластической грунтовой среде с использованием метода конечных разностей. Полученные численные результаты представлены в виде графиков. Из полученных результатов выявлено затухание параметров (касательное напряжение, деформация сдвига и угловая скорость) распространяющихся цилиндрических волн с расстоянием в упругой и упругопластической грунтовой среде. Затухание волн с расстоянием обосновано рассеиванием энергии деформирования на расширяющийся цилиндрический слой грунта. В случае нагружения за пределом упругости, пластические деформации возникают в грунте вблизи приложения нагрузок. Определены границы упругопластического деформирования грунта.
PREDICTIVE GEOMETRIC MODELS FOR HEAT-INSULATION PRORETIES OF SEMI-FINISHED FUR AND DOWN PRODUCTS
Authors:   Omsk State Technical University, Omsk, Russia, Dolgova E. Yu. , Yurkov V. Yu. ,   Omsk State Technical University, Omsk, Russia; Omsk State Pedagogical University, Omsk, Russia, Chizhik M. A. ,   Omsk State Technical University, Omsk, Russia
Published: March 2022

Статья посвящена проблеме геометрического моделирования теплозащитных свойств пушно-меховых полуфабрикатов, которые рассматриваются как сложные многокомпонентные системы с взаимно зависимыми параметрами. Целью работы является построение кусочно-постоянных прогнозирующих моделей в условиях ограниченного количества экспериментальных данных. Задача исследования формулируется как построение статических математических моделей, прогнозирующих свойства пушно-меховых полуфабрикатов в статическом состоянии. Геометрические модели строятся в виде постоянных функций в пространстве входных и выходных параметров. Пространство входных параметров разбивается на области, соответствующие кластерам на множестве экспериментальных образцов. Проведенные исследования позволяют обосновать выбор полуфабрикатов с заданными характеристиками для изготовления теплозащитной одежды. Предложенный метод геометрического моделирования может быть одним из модулей разработанного программного средства «Гиперспуск», что позволяет решать указанные выше задачи прогнозирования
MARIA, DOS ANDORES À MEDICINA CASEIRA: SEU NOME E OS NOMES POPULARES DAS PLANTAS MEDICINAIS
Authors: Oliveira Rinalda Araújo Guerra de , Nóbrega Anamélia Soares , Pereira Valdelene Nunes de Andrade
Published: March 2022

O presente artigo procura construir, a partir da nomenclatura popular das plantas medicinais, uma discussão em torno da identidade devocional mariana do cristianismo de base católica. A abordagem da religiosidade popular presente no território brasileiro mostra que o imaginário religioso compartilhado pelos praticantes do catolicismo é evidenciado nas suas várias formas de reivindicar e/ou invocar a cura das doenças. A pesquisa consiste na análise da nomenclatura presente em livros de fitoterapia, botânica e demais obras que mencionem a medicina caseira. A forma de interligação da saúde com o sagrado é ressignificada a cada sentimento que surge nas tradições do povo. Em nosso entendimento, a fé popular e o seu modo de ser vivenciada pode criar uma linguagem simbólica através do costume do povo de nomear as plantas medicinais com nomes marianos.
ULTRAMONTANISMO X ILUSTRAÇÃO: ASSISTÊNCIA E EDUCAÇÃO COMO ESPAÇOS DE DISCUSSÃO POLÍTICA E RELIGIOSA NO BRASIL – SÉCULO XIX/XX
Authors: Pinto Jefferson de Almeida
Published: March 2022

Este artigo trata das discussões entre a Igreja romana e os campos político e intelectual noBrasil sobre o tema da assistência e educação. Tomamos por referência o processo de reforma católica ultramontana, iniciado no século XIX e estendido até a formação da romanização no início do século XX. Nesse contexto, a Igreja contaria com a atuação de ordens religiosas, como foi o caso da Congregação da Missão que assumiu importantes funções no governo imperial, dentre as quais a assistência social e da educação. Tendo em vista o processo de laicização encampado pela ala política, buscou-se afastar a Igreja destas instituições, o que pode ser verificado nas discussões propostas no final do Segundo Reinado e nos projetos que se avistaram no início da República. No início do século XX, a Igreja reagiu a esse processo reaproximando-se dos intelectuais e do campo político, que, então, promoveria ações que lhe garantiria a influência nos setores em disputa.
Thyroid status in children with severe acute malnutrition
Authors: Chandrashekaraiah Shilpa , Ratageri Vinod H. , Kamath Laxmi
Published: March 2022

Objectives:

The objective of the study is to study thyroid hormone levels in children with severe acute malnutrition (SAM) and its correlation with serum total protein and albumin levels.

Materials and Methods:

A prospective cross-sectional study was carried out at Nutritional Rehabilitation Centre, Hubli, from Dec 2018 to Nov 2019. Inclusion criteria: All children in the age group of 6–59 months with SAM. Exclusion criteria: (i) Children suffering from metabolic disorders, tuberculosis, urinary tract infection, malabsorption syndrome (celiac disease), protein losing enteropathy, and nephrotic syndrome; (ii) Children with major congenital anomalies; and (iii) Children with chronic liver and kidney diseases. All enrolled children’s details of demography, clinical history, and examination were entered in a predesigned pro forma. Total triiodothyronine (TT3), total thyroxine (TT4), thyroid-stimulating hormone (TSH), and serum total protein and albumin were estimated. Data were analyzed using SPSS Version 16.

Results:

Total of 50 children fulfilled criteria during study period. Mean age of presentation was 18 ± 2.1 months with male-to-female ratio 0.8:1. The mean TT3 (ng/dl), TT4 (mcdg/l), and TSH (mIU/L) were 109.8 ± 50.6, 8.36 ± 3.7, and 2.5 ± 1.8, respectively. Mean total protein and albumin were 5.5 ± 1.4 g/dl and 2.97 ± 0.9 g/dl. Overall, 18 (36%) children had low total protein and 17 (34%) have low serum albumin. Low serum TT3, and TT4 levels were found in 11 (22%) and 14 (28%), respectively, and elevated TSH in 4 (8%) children. Low T3 was significantly associated with low albumin (P < 0.01).

Conclusion:

The impaired thyroid function and low serum T3 levels seen in SAM children were probably an adaptive change to malnutrition.
Nursing professional’s understanding and screening practices in the identification of children with autism spectrum disorder: A scoping review
Authors: Ramu Rajalakshmi , Govindan Radhakrishnan
Published: March 2022

Introduction:

Early identification and intervention of childhood autism spectrum disorder (ASD) is recognised to have a valuable impact on a child’s life. Nurses who are adequately prepared with the necessary screening practices to do early identification of the children with risk for ASD and knowledge surrounding ASD may enhance the screening practices in the child care delivery system.

Objectives:

This study was to discuss nurses’ knowledge and understanding about childhood ASD and its’ screening practices among nurses.

Methodology:

The scoping review approach was adopted for the present study utilised by reviewing electronic databases from inception to 2021.

Results:

The authors have searched 160 related studies from above-said database and found only 10 full-text studies based on the objective and research question. Based on the review, researchers understood that the Nursing Professionals have scant to moderate knowledge and understanding on childhood ASD and its ‘Screening Practices.’ Effective training programmes and continuing nursing education would hasten the early identification and intervention process in this arena.
Phytochemical analysis and antibacterial activity of Punica granatum L. seed extract against clinically isolated uropathogens
Authors: Dash Khirabdhi Tanaya , Parida Banojini , Das Sarita
Published: March 2022

The discovery of plant based drugs and dietary supplements derived from plants has accelerated in recent years. Punica granatum L. is one such plant whose products are useful in the treatment of many diseases including urinary tract infections (UTI), since it is rich in various antioxidants like vitamin C, iron and phenolic compounds. Antioxidant rich fluids are known to prevent bacteria from adhering to the walls of the bladder and urethra; as a result UTI is cured or prevented. The present investigation aims to explore the urobactericidal activity of different solvent extracts of the seeds of P. granatum. In this study, P. granatum dried seed powder was extracted exhaustively with different solvents i.e. hexane, chloroform, acetone and methanol (HPG, CPG, APG and MPG). The presence of different phytochemicals in these extracts was assessed both qualitatively and quantitatively before evaluating their urobactericidal and uroprotective potency. It was found that seeds of pomegranate have many bioactive phytochemicals like terpenoids, steroids, tannins, coumarins, glycosides, flavonoids and phenolic compounds that contribute to its significant antibacterial activity and this was proved by various methods and the zone or degree of growth inhibition was measured against different uropathogens. It was observed that APG and MPG, which are rich in hydrophilic phytoconstituents have significant bactericidal activity in comparison to HPG and CPG, which are rich in hydrophobic compounds. Since, the active phytoconstituents present in P. granatum seed have potent urobactericidal activity, it can be further explored for its tremendous bioactive potentials and also attempts should be made to safeguard and cultivate this miraculous plant which would be beneficial to the society.
NifH gene analysis of endophytic bacteria of sweet potato under various climatic locations
Authors: Ali Md. Arshad , Hafiz Md Hafizur Rahman , Salehin Ahsanul , Hayashi Shohei , Itoh Kazuhito
Published: March 2022

Beyond the nodule symbiosis process, some endophytic bacteria can convert the atmospheric nitrogen to available form for their own and the inhabiting host plants. These bacteria possess a nitrogenase enzyme complex involved in producing ammonia from atmospheric dinitrogen. The nitrogenase reductase subunit of the enzyme complex is governed by the nifH gene and is being used as a suitable marker. In the present study, the nifH gene containing endophytic bacteria had been identified from two sweet potato cultivars grown in different locations. Both the cultureindependent and culture-dependent methods were used to identify the nitrogen-fixing bacteria in sweet potatoes. The nifH sequences closest to Azospirillum, Bradyrhizobium, Herbaspirillum, Klebsiella, Kluyvera, Paenibacillus, Pseudacidovorax, Rhizobium and Sphingomonas were identified in this study. It was supposed that soils and varieties have more effects than climatic factors on nitrogen-fixing bacteria of sweet potato. These nitrogen-fixing bacteria could be utilized to develop biofertilizers helpful for sustainable agriculture.
Fast-Track Computational Access to Reaction Mechanisms Provides Comprehensive Insights into Aminolysis Postpolymerization Modification Reactions
Authors: Matsubara Kiho , Chou Li-Chieh , Amii Hideki , Kakuchi Ryohei
Published: March 2022

With the aim of providing a computational guideline for activated ester–amine chemistry, a series of activated esters commonly used in polymer synthesis have been systematically analyzed at the DLPNO-CCSD(T) level of theory by taking advantage of the recently developed density functional theory-based semiempirical method GFN2-xTB. The fast-track computational analysis based on the GFN2-xTB and DLPNO-CCSD(T) methods can explain well the experimentally observed reactivity in aminolysis postpolymerization modification reactions. Moreover, transition state search calculations can be performed with realistic model structures consisting of more than a hundred atoms, offering a new approach for reaction profiling for large molecular systems without further approximations. The realistic reaction profiling allows a preliminary assessment and visualization of the polymer effect during the postpolymerization modification at the DLPNO-CCSD(T) level of theory. This study offers a computational compass for activated ester–amine chemistry for application in postpolymerization modification reactions.
Proton Independent Electrocatalytic Transfer Hydrogenation of Styrene with [(tBuPCP)Ir(H)(Cl)] and Water
Authors: Mollik Patrick , Frantz Alexander M. , Halter Dominik P.
Published: March 2022

A new pathway of electrocatalytic transfer hydrogenation with neutral water as the H-donor was discovered using [(tBuPCP)Ir(H)(Cl)] (1) as the catalyst and styrene as a model substrate in THF electrolyte. Cyclic voltammetry experiments with 1 revealed that two subsequent reductions at –2.55 and –2.84 V vs. Fc+/Fc trigger the elimination of Cl– and afford the highly reactive anionic Ir(I) hydride complex [(tBuPCP)Ir(H)]– (2). The identity of 2 and its reactivity were further investigated by LIFDI-MS, which confirmed 2 as reactive species in the alkene hydrogenation cycle. Bulk electrolysis and chronoamperometry for electro-hydrogenation of styrene established ethylbenzene as the only product, formed with high faradaic efficiency of 96% and a turnover frequency of 1670 h–1 at an electrolysis potential of –3.1 V, with insignificant H2 formation. Importantly, the electro-hydrogenation performance of 1 remained constant upon addition of KOH to the electrolyte, which suggests a reaction mechanism that is independent of free H+. Instead, the reactive Ir-hydrides are regenerated by oxidative addition of H2O to the complex, which creates a reaction cascade that is reminiscent of metal-hydride formation in classical transfer hydrogenation systems. As such, the herein presented study on electrocatalytic transfer hydrogenation (e-TH) with H2O as the H-donor is different from the plethora of other electro-hydrogenation studies that operate via H+ reduction, often in low-pH electrolyte. These findings may inspire the general, pH independent use of H2O as H-donor in conjunction with electrochemistry, to replace isopropanol or formate as intrinsically reducing H-donors in the many existing examples of classical transfer hydrogenation.
Home-built spinning apparatus for drying agarose-based imaging mass spectrometry samples
Authors: Lusk Hannah , Levy Sarah , Bergsten Tova , Burdette Joanna , Sanchez Laura
Published: March 2022

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a useful technique for mapping the spatial distribution of molecules across biological samples. Sample preparation is crucial for MALDI-IMS; samples must be flat, dry, and co-crystallized with a matrix prior to analysis. Agar and agarose-based samples can be difficult to consistently prepare as they are susceptible to environmental changes, which can lead to inconsistent drying and wrinkling on the sample surface. Small height differences may cause low ionization of target analytes, or introduce artifacts in imaging data. To overcome the variations, a home-built robotic spinner was constructed and applied to agarose-based samples. This robotic-spinner is inexpensive, easy to assemble; and when applied to agarose-based samples, accelerated the drying process and reduced wrinkles, improving the overall quality of the resulting IMS data.
7-Aminoalkoxy-Quinazolines from Epigenetic Focused Libraries are Potent and Selective Inhibitors of DNA Methyltransferase 1
Authors: Medina-Franco José L. , López-López Edgar , Martínez-Fernández Liliam P.
Published: March 2022

Inhibitors of epigenetic writers such as DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug and probe discovery. There are many small molecules tested as inhibitors of DNMTs but, overall, they do not have potent enzymatic inhibition. Chemical companies are developing focused libraries for epigenetic targets to advance probe and drug discovery. Based on a knowledge-based approach, herein, we report the identification of two quinazoline-based derivatives identified in focused libraries with nanomolar inhibition of DNMT1 (30 and 81 nM), more potent than the positive control S-adenosylhomocysteine. The two compounds had low micromolar activity of DNMT3A and did not inhibit DNMT3B. The quinazolines reported in this work have low cell toxicity and are potent inhibitors of the epigenetic target writer G9a at the enzymatic and cellular levels. Molecular modeling helped rationalize the enzymatic inhibitory activity at the molecular level of the two compounds against DNMT1 and DNMT3A. The quinazoline-based compounds are attractive as novel potent inhibitors of DNMTs and as dual and selective epigenetic agents targeting two families of epigenetic writers.
Identification of HDAC10 Inhibitors that Modulate Autophagy in Transformed Cells
Authors: Zeyen Patrik , Zeyn Yanira , Herp Daniel , Mahmoudi Fereshteh , Yesiloglu Talha , Erdmann Frank , Schmidt Matthias , Robaa Dina , Romier Christophe , Ridinger Johannes , Herbst-Gervasoni Corey J. , Christianson David , Oehme Ina , Jung Manfred , Kraemer Oliver H. , Sippl Wolfgang
Published: March 2022

Histone deacetylases (HDACs) are a family of 18 epigenetic modifiers that fall into 4 classes. Histone deacetylase inhibitors (HDACi) are valid tools to assess HDAC functions. HDAC6 and HDAC10 belong to the class IIb subgroup of the HDAC family. The targets and biological functions of HDAC10 are ill-defined. This lack of knowledge is due to a lack of specific and potent HDAC10 inhibitors with cellular activity. Here, we have synthesized and characterized piperidine-4-acrylhydroxamates as potent and highly selective inhibitors of HDAC10. This was achieved by targeting the acidic gatekeeper residue Glu274 of HDAC10 with a basic piperidine moiety that mimics the interaction of the polyamine substrate of HDAC10. We have confirmed the binding modes of selected inhibitors using X-ray crystallography. Promising candidates were selected based on their specificity by in vitro profiling using recombinant HDACs. The most promising HDAC10 inhibitors 10c and 13b were tested for specificity in acute myeloid leukemia (AML) cells with the FLT3-ITD oncogene. By immunoblot experiments we assessed the hyperacetylation of histones and tubulin-α, which are class I and HDAC6 substrates, respectively. As validated test for HDAC10 inhibition we used flow cytometry assessing autolysosome formation in neuroblastoma and AML cells. We demonstrate that 10c and 13b inhibit HDAC10 with high specificity over HDAC6 and with no significant impact on class I HDACs. The accumulation of autolysosomes is not a consequence of apoptosis and 10c and 13b are not toxic for normal human kidney cells. These data show that 10c and 13b are nanomolar inhibitors of HDAC10 with high specificity. Thus, our new HDAC10 inhibitors are tools to identify the downstream targets and functions of HDAC10 in cells.
Terapi kompres hangat untuk menurunkan nyeri sendi pada lansia
Authors: Nugroho Heryanto Adi , Sunarsih Sunarsih
Published: March 2022

Salah satu masalah fisiologis yang sering dialami oleh lansia adalah penya  kit sendi. Penyakit sendi merupakan gangguan nyeri pada persendian yang disertai kekakuan,merah,dan pembengkakan yang bukan disebabkan karena benturan/ kecelakaan. Tujuan dari karya ilmiah ini adalah menerapkan  terapi kompres hangat  untuk menurunankan nyeri sendi pada lansia. Metode penulisan karya tulis ilmiah ini menggunakan studi kasus dengan pendekatan proses keperawatan yang mengambil 2 subyek lansia dengan keluhan nyeri sendi skala sedang yaitu nyeri skala VAS 4 sampai skala VAS 6. Intervensi keperawatan kedua subjek studi kasus dengan memberikan terapi kompres hangat mengunakan buli – buli yang diisi  air hangat dengan suhu 40 – 42 derajat celcius selama 20 – 30 menit .  Setelah dilakukan kompres hangat kemudian dilakukan evaluasi pengukuran skala nyeri dengan pengukuran skala nyeri VAS. Hasil yang didapatkan adalah adanya penurunan nyeri subjek 1 sebanyak 2 skala dan subjek 2 sebanyak 3 skala. Rata - rata penurunan skala nyeri kedua subjek studi adalah 2,5 setelah diberikan terapi kompres hangat. Kesimpulanya adalah pemberian terapi kompres hangat terbukti efektif dalam menurunkan nyeri sendi pada lansia.
Abstracts from the 18th Annual Scientific Conference of Montenegrin Sports Academy and 16th FIEP European Congress “Sport, Physical Education, Physical Activity and Health: Contemporary perspectives”: Dubrovnik, Croatia. 8-11 April 2021
Authors:   University of Montenegro, Faculty for Sport and Physical Education, Niksic, Montenegro, Bjelica Dusko , Popovic Stevo ,   University of Montenegro, Faculty for Sport and Physical Education, Niksic, Montenegro, Akpınar Selçuk ,   Nevşehir Hacı Bektaş Veli University, Department of Physical Education and Sports, Nevşehir, Turkey, Novak Dario ,   University of Zagreb, Faculty of Kinesiology, Zagreb, Croatia
Published: March 2022

N/A
Optimalisasi Yang Dilakukan Diruas Jalan Jendral Sudirman Guna Kelancaran Arus Lalu Lintas
Authors: Nugroho Muhammad Adi , Rizani Mohammad Debby , Ariawan Donny
Published: March 2022

Kenyamanan dalam berkendara merupakan hak bagi setiap pengguna jalan. Kelancaran arus lalu lintas yang tidak mengalami kemacetan sangat diinginkan bagi pengguna jalan agar terasa nyaman dan aman. Seperti halnya yang terjadi di Kabupaten Kudus masyarakat menginginkan keadaan jalan yang jauh dari kemacetan. Namun, ada beberapa ruas jalan di Kabupaten Kudus mengalami kemacetan. Tepatnya di Jalan Jendral Sudirman depan Pasar Kliwon. Penyebab kemacetan yaitu parkir on street dibahu jalan mengakibatkan tersendatnya arus lalu lintas dan terjadinya penyempitan jalan. Tujuan dari penelitian ini adalah mengevaluasi optimalisasai di ruas Jalan Jendral Sudirman depan Pasar Kliwon Kudus.Kata kunci : Kemacetan, On Street,Kudus, Kliwon, Jalan Jnedral Sudirman
Leituras em educação - volume 9
Authors: Araujo Rodrigo da Costa , Couto Cremilda Barreto , Greg´´´orio Tania Cristina da C.
Published: March 2022

Leituras em Educação - volume 9 - coletânea composta por treze artigos, reúne textos de professores pesquisadores que, entre saberes e leituras, analisam a educação por meio de um instrumental teórico para verificar a maneira como ocorre o entrelace educação com outros saberes e áreas. A pluralidade que pode ser depreendida da configuração desta obra, e que se expande no sumário e nos artigos que a compõem, remete para a diversidade e profusão da leitura e da educação. Os capítulos se orientam por um conjunto diversificado de perspectivas e questões, mas todos eles, de alguma maneira, pensam a leitura, a prática pedagógica e os educadores ou gestores envolvidos nesse processo.
Weighted Ostrowski's Type Integral Inequalities for Mapping Whose First Derivative Is Bounded
Authors: Fahad S. , Mustafa M. A. , Ullah Z. , Hussain T. , Qayyum A.
Published: March 2022

The aim of paper is to develop the inequalities for L∞, Lp and L1 norms. Applications for some special weight functions and Perturbed expressions are also determined via Chebychev functional. We recaptured the previous results for different weights.
Studi Karakteristik Dan Permodelan Termal Batuan Induk Tersier Di Cekungan Salawati, Papua Barat
Authors: Muhartanto Arista , Hamdani Ahmad Helman , Safrizal Safrizal , Fauzielly Lili , Triwerdhana Afriadhi
Published: March 2022

Cekungan Salawati memiliki cadangan minyak dan gas sejumlah 0.5 BBO dan 0.1 TCFG, diduga hidrokarbon dihasilkan dari batuan induk Tersier dan Pra-Tersier. Beberapa studi batuan induk telah dilakukan, seperti pada Formasi Sirga (Oligosen Akhir), Formasi Kais (Miosen Tengah) dan Formasi Klasafet (Miosen Akhir). Minimnya pengetahuan mengenai studi karakteristik dan pemodelan termal batuan induk Formasi Sirga dan Pre-Faumai, serta keingintahuan mengamati adanya pembalikan polaritas cekungan merupakan hal yang menarik untuk diteliti lebih lanjut. Metode penelitian menggunakan analisis geokimia petroleum yang meliputi: TOC, Rock Eval Pyrolisis, kerogen typing, vitrinite reflectance (%Ro) dengan sejumlah 9 sampel cuttings. Kekayaan material organik berdasarkan parameter TOC pada kedua formasi menunjukkan kuantitas good to very good, sedangkan parameter PY menunjukkan kualitas fair to good potency sebagai batuan induk dalam menggenerasikan hidrokarbon. Tipe kerogen komposisinya didominasi NFA yang mengindikasikan pengendapan di lingkungan oxidizing marine atau lakustrin. Data plot HI terhadap Tmax, kerogennya menunjukkan campuran tipe II/III yang mengindikasikan pengendapan yang terjadi di lingkungan transisi (fl uvio-deltaic). Kematangan Formasi Sirga dan Pre-Faumai (Oligosen) berdasarkan %Ro dan Tmax menunjukkan tingkat yang rendah. Data kematangan berdasarkan pemodelan cekungan 1D pada sumur Warir-1X dan WIR-1A (di luar daerah penelitian) memperlihatkan evolusi kematangan yang telah mencapai level yang lebih tinggi, yakni early to mid-mature yang terjadi pada kala Pliosen Tengah, dan tingkat kematangan akhir dalam oil generation yang tercapai sejak Pleistosen Awal. Adanya pembalikan polaritas cekungan yang mengarah ke Selatan sebelum Pliosen, berubah menjadi mengarah ke Utara sebagai deposenter cekungan berdampak terhadap peningkatan kematangan termal. Pada deposenter, umumnya bertindak sebagai dapur yang matang (mature kitchen) yang merupakan tempat dihasilkannya hidrokarbon.
Metode Alternatif Penentuan Densitas Batuan Reservoir Menggunakan Teknologi 3d Ct (Computed Tomography)
Authors: Gurmilang Alit
Published: March 2022

Penentuan karakterisasi fi sik batuan di laboratorium Routine Core menggunakan X-ray computed tomography (CT) merupakan teknik nondestruktif yang memungkinkan visualisasi citra struktur pori batuan yang ditentukan oleh variasi kerapatan antar butiran dan komposisi atom tanpa membuka percontoh batuan inti (core). Teknik ini dapat dijadikan bahan pertimbangan sebagai metode alternatif penentuan densitas batuan. Rekonstruksi citra yang diperoleh menggunakan metode 3D CT pada percontoh batuan inti dari alat CT Scan dibandingkan dengan data keluaran alat Spectral Gamma Ray dan Gas Permeameter pada percontoh plug untuk menghasilkan profi l nilai densitas pada batuan reservoar dengan maksud mendapatkan kesamaan pola. Dari data hasil pengukuran pada tekanan 400 psi diperoleh nilai densitas butiran/total yang diplot-silang secara linier terhadap nilai CT Number untuk diasumsikan menjadi nilai densitas matriks pada litologi batupasir dan serpih di setiap zona lapisan. Terdapat bukti yang menunjukkan adanya korelasi antara nilai densitas formasi barea sandstone dengan formasi sawah tambang. Kemudian hasil plot dari nilai total Sinar Gamma, Porositas, Permeabilitas, Densitas Butiran/Total dan CT Number ditampilkan ke dalam satu tampilan format Log Data, untuk memperoleh profi l zona lapisan dari setiap kedalaman.
Gambling Ain’t What It Used To Be: The Instrumentalization of Gambling and Late Modern Culture
Authors: Cosgrave Jim
Published: March 2022

This article addresses significant cultural macro-processes shaping legalized gambling as a mass consumer market, which also serve various state and private industry ends. The processes examined here are “instrumentalization” and rationalization, explored through the seminal formulations of Max Weber and developed further in the work of Jurgen Habermas. Instrumentalization relates to Weber’s concepts of rationalization and instrumental rationality, as well as to Habermas’s distinction between the “system” and “lifeworld”. While the phenomenon of instrumentalization is approached largely from a macro-perspective, it is understood to have effects on the lifeworld, on social action, and the formation of (gambling) subjectivities. The discussion of instrumentalization and rationalization, as broad cultural processes, contributes to the genealogy of gambling in (late) modern culture. It also serves to develop a particular theoretical trajectory within critical gambling studies and indicates themes that could be opened up for further analysis.