bluuebunny/crossref_metadata_2025 huggingface dataset:
Phytochemistry and Pharmacology of Indian Traditional Plant Hyssop
(Hyssopus officinalis L.): A Review
Authors: Kumar Vanktesh , Kaur Navjot , Kaur Arvinder , Wadhwa Pankaj
Published: August 2022

Hyssopus officinalis is a traditional medicinal plant that belongs to the family Lamiaceae, which has been used from centuries for various purposes like carminative, expectorant, cough reliever. It has been used for the treatment of numerous diseases in patients such as ulcers, asthma, jaundice, leprosy, dropsy, bronchitis, COPD, diabetes, AIDS, bacterial and fungal infections as an herbal remedy due to its fewer side effects and is more efficacies than other traditional medicine. Major classes of chemical compounds found in H. officinalis essential oil are bicyclic monoterpenes, monoterpenoids, acyclic monoterpenes, phenolic monoterpenoids, monocyclic monoterpenes, monocyclic sesquiterpenes, tricyclic sesquiterpenes, bicyclic sesquiterpenes, tricyclic sesquiterpenoids, straight chain saturated hydrocarbons. Some of the major chemical constituents present in the H. officinalis are β-pinene, α-pinene, 1, 8-cineole, apigenin, diosmin, caffeic acid, rosmarinic acid, cis-pinocamphone, trans-pinocamphone, iso-pinocamphone, pinocarvone, which are responsible for its various pharmacological activity. Various studies have been performed on the pharmacological activity of its extract, such as antioxidant, antimicrobial, anti-diabetic, anticancer, antiviral, anti-inflammatory, analgesic, anti-leishmanial, anthelmintic, anti-protozoal and anti-anxiety. Recently, it is use as an anticancer agent has been demonstrated by studying its cytotoxic and apoptotic effects on breast cancer and colon cancer cells. It is used as a potent antibacterial and antifungal agent was studied on the antibiotic-resistant bacterial and fungal strains recently, which can be further useful in developing herbal medicine against AMR. It is an excellent natural antioxidant due to the presence of polyphenolic compounds, and H. officinalis is used in various food industries as a source of natural antioxidants, which has minimum side effects as compared to artificial antioxidants. Furthermore, the pharmacological activity of these individual chemical constituents in H. officinalis extract still needs to be investigated for identifying the effectiveness of this plant in the natural treatment of various diseases. This review aims to collect various data regarding the traditional herbal plant hyssop (Hyssopus Officinalis), including its photochemistry, chemical structures of the phyto-constituents and pharmacological profile, along with all the pharmacological models. This plant has significant importance in the health industry, so further studies are required on its effective usage against various emerging health problems, including COVID-19, cancer, diabetes, AMR.
Data Loading and Pre-Processing
Authors: Mittal Mamta , Battineni ​Gopi , Usharani Bhimavarapu , Goyal ​Lalit Mohan
Published: August 2022

This chapter provides details about importing some predefined Python
libraries, various data pre-processing techniques, and visualization techniques using
various modules in python.
O contributo do profissional da informação na curadoria digital
Authors: Oliveira Alcinete Maquine Carvalho , Rosa Ana Isabel Sousa , Gomes Rosangela da Silva
Published: August 2022

The information professional is gaining more and more space in the current information society. Information and communication technologies appear to facilitate the performance of work in the digital environment. With the increasing amount of information, either digitized or born digital, the care of digital objects has become urgent. Digital curation appears as an alternative in the care of digital objects, ensuring that they have a longer life and can be used. It is believed that activities related to digital curation have required constant updates and other competencies for the information professional. Therefore, we intend to know: what are the information professional's practices that contribute to digital curatorship? General Objective: To identify which types of information professionals perform activities related to digital curatorship. Specific objectives: to highlight the literatures that deal with the information professional in digital curatorship; to verify the necessary competences for the information professional to act as digital curator; to specify the similar and different aspects in the typologies of the information professional. Results: Most digital curators are librarian, archivist or museologist professionals, with master's degrees in the areas of librarianship, records management, archivists or in information science. Few specialize or have master's degrees in digital curation or data curation. Some of the activities that the digital curator performs include the following services: creating metadata; accessing, collecting and manipulating content; discarding; maintaining resources; developing policies and managing data plans and procedures for digital content. Conclusion: Digital curation is important to ensure the long life and integrity of the digital object, so organizations adapt to their reality, life cycle models to work with these digital objects. The specialized training for digital curators is directly linked to the areas of Librarianship and Information Science. This research highlights the type of information professional: the librarian, who most performs activities related to digital curation.
O memorialista e seu sacrifício memória, entrevista e documento em perspectiva interdisciplinar
Authors: Santo Sílvia Maria do Espírito , Oliveira Cláudia Leonor Guedes de Azevedo , Aguiar Herika Maria da Silva , Domingues Luís Paulo Césari , Venturi Guilherme Mapelli
Published: August 2022

This article analyzes two common practices involving researchers in Information Science, Journalism and History: the document and the interview. These practices are supported by the concepts of memory and the search for interdisciplinarity. The methodology originates from the elements identified in the regional studies, using the collection of oral testimony, in an exploratory character.Of the theoretical and practical objectives, the investigative contribution stands out, basedon the assumptions that memory calls for historical reconstructions that are present today, being projected, from the past, and reinterpreted by agents of different academic and cultural expressions. The results are enumerated as to the inferences about the documentary study of regional history, which highlight the uses of the interview and the document, which is, at the same time, individual and collective, due to the perspectives inserted in the constructions, reconstructions and social fractures of the past, especially in the figure of the local memorialist.
Trend Analysis of Positive Sentiment for Special Autonomy for Papua on Twitter
Authors: Lawelai Herman , Sadat Anwar
Published: August 2022

Technological Advances encourage internet users on mobile phones or other communication tools to access or obtain information via social media, including conversations on social media on Twitter, about the implementation of Provincial special autonomy. This research method utilizes Twitter data crawled by the Drone Emprit Academic application with the keyword " special autonomy of Papua." The study analyzed 170,641 mentions collected on Twitter with the tweet "Special Autonomy for Papua." The results of this study show that the community's response to Papua's special autonomy from February 1, 2021, to February 1, 2022, was 170,641 mentions. The results of this study showed the public reaction to conversations related to Papuan special autonomy on Twitter that positive sentiment dominated with 124,181 (73 percent) mentions, followed by negative sentiment with 37,570 (22 percent) mentions, and neutral sentiment with 8,890 (5 percent) mentions. The results of this study contribute to understanding the dominant topic of Papua's special autonomy, which can be used as a reference by the government in supporting policies and improving service quality through Papua's special autonomy.
Exploring L1-L2 Relationships
Authors: Sparks Richard L.
Published: August 2022

This book traces and summarizes the author’s theoretical insights and empirical findings in the field of foreign language education. The volume explores individual differences in L1 ability and their connection to L2 aptitude and L2 achievement, L2 anxiety as an affective or cognitive variable, and the relationship between L1 and L2 reading.
Exploring frailty, comorbidity and in-hospital mortality in older COVID-19 patients using machine learning: an observational study of administrative data (Preprint)
Authors: Heyl Johannes , Hardy Flavien , Tucker Katie , Hopper Adrian , Marchã Maria J.M. , Navaratnam Annakan V. , Briggs Tim W.R. , Yates Jeremy , Day Jamie , Wheeler Andrew , Eve-Jones Sue , Gray William K.
Published: August 2022

BACKGROUND

Older adults have worse outcomes following hospitalisation with COVID-19, but within this group there is substantial variation. Although frailty and comorbidity are key determinants of mortality, it is less clear which manifestations of frailty and comorbidity are associated with the worst outcomes.

OBJECTIVE

We aimed to identify the key comorbidities and domains of frailty that were associated with in-hospital mortality in older patients with COVID-19.

METHODS

This was a retrospective study that used the Hospital Episode Statistics administrative dataset from 1st March 2020 to 28th February 2021 for hospital patients in England aged 65 years and over. Frailty was assessed using the Dr Foster Global Frailty Scale (GFS) and comorbidity using the Charlson Comorbidity Index (CCI). Descriptive statistics techniques were used to determine mortality rates according to the demographic, frailty and comorbidity profile of patients. Features were selected, pre-processed and inputted into a random forest classification algorithm to predict in-hospital mortality.

RESULTS

In total 215,831 patients were included. The frailty and comorbidity measures significantly improved the model’s ability to predict mortality in patients, when used alongside age, sex, deprivation, ethnicity, discharge month and year, region, disease severity and hospital trust. The most important frailty items in the GFS were dementia/delirium, falls/fractures and pressure ulcers/weight loss. The most-important comorbidity items in the CCI were cancer, heart failure and renal disease. The best-performing model had a predictive accuracy of 82% as well as an area under the curve of 0.90 and the features included all the aforementioned covariates.

CONCLUSIONS

The physical manifestation of frailty and comorbidity, particularly a history of cognitive impairment and falls, may be useful in identification of patients who may need additional support during hospitalisation.
Fraksinasi dan Identifikasi Senyawa Volatil Asap Cair Cangkang Sawit
Authors: Halim Muhammad , Darmadji Purnama , Indrati Retno
Published: August 2022

Palm kernel shell is one residue material of oil palm process industry. Total palm kernel shell were sufficient and could be processed into liquid smoke. The liquid smoke has been found to contain compounds functioning as smoky product improvement. This research was to identify volatile compound components existing in the liquid smoke of pabn kernel shell. This research started from liquid smoke production by pirolisa at 400 °C for 90 minutes and fractionation of temperature variation <100°C(F1), 101-125°C(F2), 126-150°C(F3), 151-175°C(F4), and 176-200°C(F5). The results of fractionation were analysed for the following chemical compositions: phenol, carbonyl, acid, and pH. The volatile compound components of liquid smoke was identified using GC-MS. The result of research indicated that F2 had highest content was 82.26%. The content of phenol, carbonyl, and acid of liquid smoke were 3.86%, 12.48%, and 12.41% respectively. The results of fractionation of phenol content low in F1 increased to F5 of 0.73%. The content of carbonyl was lower and the lowest in F5 was 3.61%. The content of acid was higher and the highest in F5 was 63.81% along with pH of liquid smoke (F0) of 3.29 and more acidy in F5 of 2.69. The result of GC-MS indicated that the liquid smoke consisted of at least 14 high components. Some of them were phenol, 2-methoxy 4-methyl phenol, 2-furan carboxaldehyde, 1,2-benzenediol, 2-methyl phenol, 4-ethyl 2-methoxy phenol, 1,2,3-trimethoxy phenol, 3-methoxy 1,2-benzenediol, 3-methyl 1,2-cyclopentanedione, 1,2,3-trimethoxy 5-methyl benzene, dan 2,3-penthanedione
Aktivitas Antioksidan Ekstrak Buah Mengkudu (Morinda citrifolia, L)
Authors: Rohman Abdul , Riyanto Sugeng
Published: August 2022

This research aimed to determine antioxidant activity of Morinda citrifolia, L fruit extracts. Morinda citrifolia, L fruit was ground, extracted by methanol, and partitioned by using chloroform and ethyl acetate to recover extracts of methanol, chloroform and ethyl acetate respectively. These extracts were diluted to various concentrations i.e. 1, 5, and 10 %, and were determined their antioxidant activities by linoleic-thiocyanate method. The result showed that extracts of Morinda citrifolia, L fruit had antioxidant activity in the order of ethyl acetate extract > chloroform extract > methanol extract. Antiradical activity tests were carried out by using DPPH (2,2-dipheny1-1-piaylhydrazil) method, the results showed that ethyl acetate extract, chloroform extract, and methanol extract revealed IC50 46,7, 227,7 and 888,6 pg/ml, respectively.
Pengaruh Konsentrasi Xilosa dan Kosubstrat Terhadap Produksi Xilitol oleh Candida shehatae Way 08
Authors: Yulianto Wisnu Adi , Kuswanto Kapti Rahayu , Tranggono Tranggono , Indrati Retno
Published: August 2022

The objectives of the research were to determine the optimum cultivation condition of initial xylose concentration, type of cosubstrate and ratio of cosubstrate to substrate (xylose) for xylitol production by Candida shehatae WAY 08. The initial xylose concentrations were varied within the range of 2-14 %. The cosubstrates were arabinose, galactose, glucose, and mannose. Ratios of cosubstrate to xylose were the range of 1:6 - 3:6 %. The fermentation was performed at 30`C in a 500 ml Erlenmeyer flask placed in a shaker incubator at 200 rpm for 72 h. Biomass concentration was determined by drying method. Xylose, cosubstrate and xylitol concentrations were determined using HPLC. The result indicated that with the medium containing 6 % xylose produced the highest product yield ( 0,75 g/g) and xylitol volumetric productivity was 0,73 g/Lh. The addition of cosubstrate of arabinose increased xylitol production, while the addition of glucose, galactose, and mannose decreased its productions.
Kebutuhan Riset Pengelolaan Sumberdaya Air (SDA) di Masa Depan : Sebuah Gagasan Awal
Authors: Arif Sigit Supadmo
Published: August 2022

During some later years, several calamities had occurred several times in the country. Landslides and floods come during wet season and in the opposite drought happened in dry season. Just wet season end, drought comes and threat all activities of human life in most region in the country. In some places all of these conditions change very quickly. Mostly, all those occurred due to inappropriate management of water resources. This paper aims at discussing some prospects of water resources research in the future. One knows that the existence of water resources in the earth is a complex system and satisfies some certain natural laws to form an natural equilibrium, so, it more easily if management of water resources research is approached by applying system analysis. The paper also discussed application of new paradigm as well as several new research methods in social, economical and engineering aspects in water resources management.
Komponen Kimia dan Anatomi Tiga Jenis Bambu dari Seram, Maluku
Authors: Loiwatu Mery , Manuhuwa Elyazar
Published: August 2022

As a versatile plant, the basic properties of bamboo are various, depending on species, site, and position inside the stem. This study was conducted at three sites (Buria, Morekao, Tala), on three species (Dendrocalamus asper, Schizos- tachyium brachycladum, Schyzotachium lima), and three positions of the stem (base, middle, top). Objective of the study was to measure chemical component and anatomical feature of the three species of bamboos of West Ceram’s Sub-district (Taniwel, Piru, Kairatu) and three parts of stem (base, middle, top). Factorial experiment in split plot design was applied in the study with 3 replications. Result of the study indicated that there was a significant effect of location on the lignin content, diameter of the fiber and fiber cells lumen, and proportion of parenchyma cells; species of bamboo to the length and diameter of fiber cells; and portion of stem to the extractive soluble in hot water, soluble in alcohol benzene, length and diameter of fiber cells, and diameter of fiber lumens. Extractive soluble in cold water was 3.10-3.79 %; hot water was 5.43-6.23 %; alcohol benzene was 3.37-4.10 %; alpha cellulose was 44.22-46,94 %; holocellulose was 71.97-75.57 %; lignin was 26.00-27.37 %; length of fiber cell was 3.40-3,96 mm; diameter of fiber cell was 4.34-4.91 micron; diameter of fiber cell lumens was 2.74-3.23 micron; cell wall thickness of fiber cell was0.76-0.91 micron; proportion of parenchyma cells was 51.95-56.85 %; proportion of fiber cells was 27.81-62.66 %;and proportion of pores was 12.39-14.60 %.ABSTRAKSebagai tanaman serbaguna, sifat dasar bambu bervariasi menurut jenis, tempat tumbuh dan posisi didalam batang. Penelitian dilakukan pada 3 lokasi (Buria, Morekao, Tala), terhadap 3 jenis bambu (Dendrocalamus asper, Schizos- tachyium brachycladum, Schyzotachium lima), dan 3 posisi dalam batang (pangkal, tengah dan ujung). Tujuan pene- litian adalah untuk mengukur komponen kimia dan anatomi 3 jenis bambu (Dendrocalamus asper, Schizostachyium brachycladum, Schyzotachium lima) asal 3 kecamatan Seram bagian barat (Taniwel, Piru, Kairatu), dan 3 bagian batang (pangkal, tengah dan ujung). Percobaan faktorial dalam rancangan petak terpisah digunakan dalam penelitian dengan 3 ulangan. Hasil penelitian menunjukkan pengaruh signifikan lokasi terhadap kadar lignin, diameter sel serat dan rongga sel serat dan proporsi sel parensim; jenis bambu terhadap panjang dan diameter sel serat; posisi dalam batang terhadap kadar ekstraktif larut air dingin, ekstraktif larut alkohol benzen, panjang dan diameter sel serat, dan diameter sel serat. Ekstraktif larut air dingin berkisar 3,10-3,79 %; larut air panas 5,43-6,23 %; larut alkohol benzen3,37-4,10 %; alfa selulosa 44,22-46,94 %; holoselulosa 71,97-75,57 %; lignin 26,00-27,37 %; panjang sel serat 3,40-3,96 mm; diameter sel serat 4,34-4,91 mikron; diameter rongga sel serat 2,74-3,23 mikron; tebal dinding sel serat0,76-0,91 mikron proporsi sel parensim 51,95-56,85 %; proporsi sel sel serat 27,81-62,66 %; dan proporsi sel pori12,39-14,60 %.
A Study on Factors Influencing the Hydrodistillation of Triphasia trifolia Essential Oil
Authors: Huynh Ngo Phuoc-Sang , Luu Xuan-Cuong , Huynh Minh-Thuan , Tran Thien Hien , Dao Tan Phat , Le Tien-Xuan
Published: August 2022

The present study attempted to evaluate the suitable conditions for essential oil extraction from the fruit of Triphasia trifolia using hydrodistillation technique. The effect of various factors such as material size, solvent to solid ratio, heating temperature and distillation time, state of maturation, and fruit preservation on the oil yield was investigated. The physicochemical property, chemical composition, and biological properties were accessed. The highest yield of essential oil (7.9 mL/kg dry matter) from T. trifolia was obtained at optimal conditions such as fine particle size, solid to solvent ratio of 1:5, temperature oil bath of 140 °C, and distillation time of 3 h. The state of maturation of the fruits significantly affects the essential oil yield and insignificantly influences chemical composition based on the gas chromatography-mass spectrometry (GC-MS) analysis. It was found that the essential oil yield decreases significantly when ripened fruits are not kept in cool conditions before distillation. It implied that ripened fruits should be immediately processed or kept in cool storage to maintain the essential oil yield. Our findings will help produce high-quality essential oil from T. trifolia at a pilot or industrial scale.
GC-MS Based Metabolite Profiling and Antibacterial Activity of Torch Ginger (Etlingera elatior) Flowers Extract
Authors: Maser Wahyu Haryati , Purwoko Agus , Yuliana Nancy Dewi , Lubis Linda Masniary , Khatib Alfi
Published: August 2022

Torch ginger (Etlingera elatior) flowers are well known for their antibacterial effects against Staphylococcus aureus, however, the active compounds are still unknown. The purpose of this study was to conduct GC-MS-based metabolite profiling of torch ginger flower and identify compounds correlated with its S. aureus antibacterial activity using Orthogonal Projection to Latent Structure (OPLS). Using the well diffusion method, the antibacterial activity of ethanol extract, hexane, chloroform, and ethyl acetate fractions with a concentration of 80 mg/mL were investigated. The ethyl acetate fraction inhibited S. aureus growth the most (diameter of inhibition zone, DIZ 13.00–13.20 mm), while the hexane (DIZ 9.55–10.05 mm) and chloroform (DIZ 10.00–11.00 mm) fractions had moderate inhibitory activity, but the ethanol extract had no antibacterial effect. Using OPLS analysis, the GC-MS metabolite profile of all extracts and fractions was linked with the profile of antibacterial activity. This analysis revealed that Dodecanoic acid, 5-Tetradecene, and n-Hexadecanoic acid were identified as the compounds that were significantly connected with antibacterial activity.
Estimation of the Energy Potential by Anaerobic Digestion of Food Waste at Nangui Abrogoua University : Codigestion of Food Waste With Cow Dung
Authors:   Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR Sciences Fondamentales et Appliquu00e9es, KOUAKOU ADJOUMANI RODRIGUE ,   Universitu00e9 Nangui Abrogoua,   02 BP 801 Abidjan 02, Cu00f4te du2019Ivoire., ABOLLu00c9 ABOLLE ,   Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR Sciences Fondamentales et Appliquu00e9es ; Universitu00e9 Nangui Abrogoua ; 02 BP 801 Abidjan 02, Cu00f4te du2019Ivoire., KOUADIO MARC CYRIL ,   Institut de Recherche sur les Energies Nouvelles, Universitu00e9 Nangui Abrogoua, Abidjan, Cu00f4te du2019Ivoire, AKOSSI MOYA JOELLE CAROLE ,   Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR Sciences Fondamentales et Appliquu00e9es ; Universitu00e9 Nangui Abrogoua ; 02 BP 801 Abidjan 02, Cu00f4te du2019Ivoire., DONATIEN EHOUMAN AHISSAN ,   Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR Sciences Fondamentales et Appliquu00e9es ; Universitu00e9 Nangui Abrogoua ; 02 BP 801 Abidjan 02, Cu00f4te du2019Ivoire., KOUASSI EDMOND KONAN ,   Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR Sciences Fondamentales et Appliquu00e9es ; Universitu00e9 Nangui Abrogoua ; 02 BP 801 Abidjan 02, Cu00f4te du2019Ivoire.
Published: August 2022

The food wastes of the Nangui Abrogoua University are rich in organic matter that can promote the production of biogas through anaerobic digestion. These wastes are favorable for the anaerobic digestion process. This study aims at estimating the energy potential of the food wastes of the University Nangui Abrogoua by the production of biogas following the process of anaerobic digestion batch. The biogas from this food waste is estimated to be 10.79 m3 or 10790000 mL over a period of 30 days. This is equivalent to an energy potential of 75.58 kWh. These results obtained indicate that the food waste of the University Nangui Abrogoua is an important source of renewable energy.
Solutions to develop the cultural market in the context of integration
Authors: Phuong Phung Thi Thuy
Published: August 2022

The cultural market is a market for specific goods in the field of ideological culture. The birth and development of the cultural market in Vietnam are also later than that of other countries in the world. Cultural products and services are special goods that meet the cultural and spiritual needs of people. In addition to the market role in the socio-economic development of the country, the cultural market also plays an important role in comprehensive human development in the context of Vietnam's current international integration. Therefore, the content of cultural market management needs to be properly identified, enough to enhance the effectiveness of state management and promote the cultural market to develop in the right direction to meet the cultural and spiritual needs of the whole world society.
Stone Material is always in Thanh Hoa
Authors: Thang Pham Van
Published: August 2022

The remains of stone material in religious architectures in Thanh Hoa are relatively significant today, scattered in temples, mausoleums, and ancient citadels. However, stone worshiping objects account for a small number compared to relics such as horse statues, elephant statues, tiger statues, animal spirits, and human statues and are in danger of being lost or destroyed. Researching stone worshiping objects in religious relics to get an overview of one of the special types of relics as well as propose some necessary measures to preserve and promote their values properly. cultural property left by our forefathers.
A Survey: Internet of Things (IOT) Technologies, Applications
Authors: B C Bhavana , C T Vathsala Gowda , B H Rakshitha
Published: August 2022

Abstract: Internet of Things is influencing enormously in our lifestyle from the day we begin to the day we end. IOT is an immense network with connected devices. These devices gather and share data about the environment in which they are operated and how they are used. Internet of things is a very intense concept in which the real world of things is connected to implicit world of information technology. The paper tell about the internet of things such as home auto machines, sensors makes our life more comfortable. Analytics is performed on the data from the IoT therefore the valuable information is extracted as per requirement and visualization to generate actionable intelligence and create value.
Synthesis of Novel Oxo Pyrimido Pyrimidine and Their Derivatives
Authors: Jadhav Madhav S. , Jadhav Anilkumar G. , Kale Prashant S. , Sirsat Shivraj B.
Published: August 2022

Abstract: Pyrimidine derivatives are synthesized to possess various pharmacological and biological activities. In the present work, we have synthesized 3-(4-methoxyphenyl)-1-phenyl prop-2-en-1-one (1) (chalcone) by using 4-methoxybenzaldehyde and acetophenone in the presence of alcoholic KOH by Claisen-Schmidt condensation reaction. After purification and characterization by physical and spectral methods, The synthesized chalcone have been converted into 6-(4-methoxyphenyl)-4- phenyl-1,6-dihydropyrimidin-2-amine (2) by treating with guanidine nitrate in the presence of alcoholic KOH. The structure (2) has been characterized by spectral analysis. The synthesized compound (2) is further reacted with ethyl 2-cyano-3, 3-bis (methylthio)acrylate in the presence of catalytic amount of potassium carbonate in DMF under reflux condition to givenovel 2- (4-methoxyphenyl)-8-(methylthio)-6-oxo-4-phenyl-1,6,9,9a-tetrahydro-2H-pyrimido[1,2-a] pyrimidine-7-carbonitrile(3) in good yields. The compound (3) possesses replaceable methylthio (-SCH3) group at 8 position. The compound (3) is further reacted with various nucleophiles like substituted aromatic amines, aromatic phenols, hetryl amines and active methylene compounds to give 2-(4-methoxyphenyl)-8-substituted-6-oxo-4-phenyl-1,6,9,9a-tetrahydro-2H-pyrimido[1,2-a]pyrimidine-7-carbonitrile in good yields.
Dark Knight Application using Android
Authors: Susmitha E. , Mahendra A.
Published: August 2022

Abstract: This paper providing an Android App, which makes easier for traveler to travel to their destination. The need for security and safety is of high demand today. Especially for women, It is required to provide an assurance they are being protected. This app provides this need and assurance. It makes use of Firebase phone authentication which helps us to get authenticated with minimum effort. It privies a Location update service that allows the guardians know about the where about of the ward. It also contains a chat box in which we can dynamically update our location by sending messages to our guardians. Finally this security app is a nice watcher of our loved ones and ensures of their security and safety.
Optimization of Different Mix-Proportions of Foam Concrete
Authors: Thakur Sagar Singh , Pandey Kushagra
Published: August 2022

Abstract: Lightweight aggregate concretes are widely incorporated in construction and development. As we know, pre-foaming method or the mixed-foaming method can be used to make foamed concrete. Here, OPC and PPC cement are chosen mainly based on their different properties effect the light concrete. In this study, foam concrete is prepared according to different variation in percentage of foaming agent and water. The ratio of foaming agent and water were varied in three different percentage which are 90:10, 80:20 and 70:30 (foam: water) to achieve better trial which is lighter in weight and provide better strength. All of the concrete mixtures were tested at room temperature. This is been evaluated by test such as compression strength, flexural and split tensile. Here, evaluation of percentage of foaming agent required to exert better strength.
A Note on the Wedderburn Decomposition and Unit Group of the Semisimple Group Algebra FpSn
Authors: Mittal Shubham
Published: August 2022

Abstract: In this short note, we give an algorithm to compute the unit group of a semisimple group algebra for any . To show the practicality of the algorithm, we explicitly find the unit groups of the semisimple group algebras
ICANN: A Study of Its Working
Authors: Pushyamitra M
Published: August 2022

Abstract: The Cyberspace is a borderless space and has led to many legal and jurisprudential problems and challenges for the enactment, enforcement and interpretation of laws. Governance of internet has always been a debated issue around the world. The internet society promotes net neutrality, open access, internet resilience and stability, freedom of expression, privacy and identity of the users. The World Wide Web Consortium (W3C) is an international community where Member organizations and the civil society work together to develop Web standards. The governance structure and processes introduced by IGF provide opportunities to integrate social media ways that enhance both remote and local participation in the yearly forums and throughout the year.
Waiter Robot with Smart Ordering System
Authors: Sheikh Heena , Sutar Devendra , Naik Sanjana , Sonnad Ashutosh , Kumbar Kiran
Published: August 2022

Abstract: Today, technology is being used to make improvements in every domain. Due to rapid development of technology, in the field of work the robots have replaced human labor and solved many related problems. Young people choose to enjoy a variety of food outside which led to emergence of new ideas in the food service industry. Nowadays the demand for intelligent food delivery systems is increasing at a rapid rate. This idea is leading towards the improvement of the cost and efficiency of the food delivery system. This project aims at designing a low cost, efficient autonomous robot with a smart ordering system.
Kitābah Online Learning Strategy With The Scamper Method
Authors: Salimatul Fuadah  , Shodiq Muhammad Jafar
Published: August 2022

This research aimed to examine projects in creative Arabic writing by online learning with the scamper method. The object of research in this study was UIN Sunan Kalijaga's 4th semester of Arabic language and literature students. The research design used was True - Experimental Designs. Data collection techniques were observation, interviews, questionnaires, tests, and documentation. Research showed that the process of learning creative Arabic writing using online-based Scamper methods in kitābah courses is declared effective, with the results of the pretest test -t independent simple test showed that sig. 0.003 < 0.05. While the results of the posttest test-t independent simple test showed sig. 0.00 < 0.05. Strengthened by the analysis of the test-paired sample test showed a level sig. 0.00 < 0.05 so that it was concluded under Ha accepted and there was a significant difference. As for the results of learning to write creative Arabic with the scamper method after treatment in the experimental group, this can be seen from the increase in the experimental group by 18% and the control group only by 9,2% . This proved that there were significant differences before and after using learning strategies with scamper methods based on online experiment classes in writing creative Arabic on kitābah courses.
Planejamento pedagógico para o espaço-tempo aula: reflexões sobre o ato de planejar durante o ERE
Authors: Anecleto Úrsula Cunha , Silva Obdália Santana Ferraz
Published: August 2022

O planejamento pedagógico constitui-se mais do que uma atividade organizacional do trabalho do professor, pois o ato de planejar envolve interrelação entre aspectos educativos e realidades sociais, políticas, culturais vivenciadas pelos atores educacionais. Nesse sentido, integra as atividades da escola aos contextos sociais, com vista à transformação dessas realidades. Assim, pressupõe uma ação colaborativa, reflexiva e integradora. Por essa perspectiva, este artigo apresenta discussão que atende a um dos objetivos específicos de uma pesquisa de pós-doutorado, a saber: conhecer como ocorreu o planejamento pedagógico do professor para a realização de aulas de Língua Portuguesa durante o Ensino Remoto Emergencial (ERE). Metodologicamente, parte-se de uma abordagem qualitativa e método análise de conteúdo. Os participantes desta pesquisa foram 36 professores que integram o sistema público de ensino, tanto da esfera estadual quanto da municipal, em uma localidade no interior da Bahia. Os achados da pesquisa nos mostraram a existência de desafios pedagógicos para a realização do planejamento colaborativo e participativo durante o ERE devido a alguns fatores, dentre eles a ampliação na carga horária de trabalho do professor, a modificação na atribuição do papel docente e a necessidade de formação do professor para vivenciar o contexto educacional on-line.
Livros didáticos na Educação Infantil: usá-los ou não?
Authors: Souza Isaura Lays Sá Fernandes de , Bastos Ana Paula Solino , Mota Maria Danielle Araújo
Published: August 2022

Neste trabalho, objetiva-se analisar o papel da brincadeira e da participação infantil em atividades propostas em um livro didático da Educação Infantil. Metodologicamente, foi realizada uma pesquisa qualitativa do tipo documental, a qual tomou como objeto de estudo o livro manual do professor da Pré-escola para crianças de quatro anos. O livro foi analisado por meio da Análise Textual Discursiva, a partir das seguintes categorias: a) O brincar como ferramenta pedagógica e b) Participação e o desenvolvimento das múltiplas linguagens infantis. Dentre os resultados, constatou-se que apesar da boa qualidade gráfica da coleção e das ilustrações retratarem a diversidade cultural do nosso país, as atividades sugeridas para crianças de quatro anos apresentam exercícios similares àqueles propostos para os anos iniciais do ensino fundamental, estimulando de forma precoce a alfabetização e o letramento, por explorar exclusivamente a literacia e a numeracia. Sendo assim, a brincadeira e a participação infantil considerados, desde então, como eixos fundamentais a serem explorados nesta etapa da educação básica, aparecem de forma superficial, descaracterizando a criança enquanto sujeito ativo que aprende brincando e interagindo, os quais por meio das experiências é que desenvolve o pensamento simbólico e produz cultura.
Tempos sombrios entre nós: proposta de aula e de atividade para o ensino de História através da distopia
Authors: Furlanetto Gabriel Henrique de Oliveira , Oliveira Neto Wilson de
Published: August 2022

A primeira metade do século XX se caracteriza por ser um dos períodos mais tenebrosos da História, pelo motivo de o Crash de 1929, a Primeira e Segunda Grande Guerra configurarem grandes decadências. Dado o grande sofrimento desse período, uma das consequências foi a ascensão do gênero literário de distopia, que se trata de inculcar no futuro o pessimismo humano. Por essa questão, esse artigo visa demostrar, através de revisão bibliográfica, como as obras dessa literatura podem servir para o ensino de História através da temática referente aos sofrimentos da primeira metade do século XX, na proposição de uma aula temática para o Novo Ensino Médio e de uma atividade didática utilizando dois exemplos de obras literárias. Nesse assunto, será dissertado sobre o imaginário social do século XIX para que se possa compreender a grande ruptura de experiências europeias entre os oitocentistas e os novecentistas. As informações desse artigo, que foram possibilitadas através dos incentivos do Pibid e experiências de um bolsista, poderão servir para aulas e atividades avaliativas. Dessa forma, será observado como a distopia e a incorporação imaginativa dessa em sala de aula poderá colaborar para o aprendizado de História e para com a prática do criticismo.
Estágio supervisionado em Matemática: mapeamento e reflexões da formação docente em tempos de pandemia da covid-19
Authors: Silva Laís Alves , Souza Kellen Cristina , De Grandi Alessandra Bueno
Published: August 2022

Com a suspenção das aulas e atividades presenciais, devido à pandemia de covid-19, formas alternativas de estágio nos cursos de licenciatura têm possibilitado o desenvolvimento do saber por meio de metodologias que vão além do ambiente escolar formal. Nesse sentido, o objetivo deste trabalho foi realizar uma análise das experiências vivenciadas por discentes de licenciatura em estágios supervisionados no ensino de Matemática no Brasil durante a pandemia da covid-19. Como metodologia, foi realizada uma pesquisa bibliográfica das publicações de artigos científicos e/ou trabalhos completos publicados em eventos científicos, em 2021, sobre estágio supervisionados na pandemia. A pesquisa foi realizada por meio de buscas no repositório da base de dados Google Acadêmico, utilizando os seguintes descritores: “estágio”, “ensino remoto” e “licenciatura em matemática”. Foram selecionados 9 artigos. A seleção dos artigos ocorreu com base na análise prévia do título e resumo, seguido de uma análise detalhada do trabalho completo. Com base nos relatos, notou-se que os estagiários de Licenciatura em Matemática puderam, durante o Ensino Remoto Emergencial, vivenciar a experiência e os desafios da prática docente e que o uso de diferentes Tecnologias Digitais de Informação e Comunicação foi crucial para a realização das atividades.
Comparative Study of Realistic Optimism between India and Japan University Students
Authors: Nishaat Aneesah
Published: August 2022

This study aimed to determine the differences in realistic optimism between Indian and Japanese university students using the realistic optimism scale. Indian students (n = 361; 193 males and 168 females) and Japanese students (n = 390; 172 males and 218 females) participated in the questionnaire survey. A t-test and analysis of variance (ANOVA) were used to compare the realistic optimism between the two participant groups. The results of the t-test indicated significant differences between Indian and Japanese students regarding realistic optimism, with Indian students scoring higher in the flexibility and future orientation dimensions. No significant difference was observed in the will/courage dimension. The ANOVA results showed a significant difference between India’s and Japan’s male and female students regarding future orientation and flexibility. However, no significant difference was found in terms of will/courage between Indian and Japanese male students and between Indian and Japanese female students. The results also revealed that Indian students, male and female, scored higher on overall realistic optimism than Japanese male and female students. The findings are discussed in the context of cross-cultural studies. Indian students scored higher in flexibility resulting from a multicultural society that requires them to understand each other and be flexible. Indian students’ higher scores in future orientation refer to a strong desire to realize their goals and dreams.
Immersive Research Experiences: Influences on Science Teaching Motivation and Practices
Authors: Hubbard Lindsey , Jackman-Ryan Stella , Thomson Margareta
Published: August 2022

The push for inquiry-based learning in science classrooms has been met with anxiety and oftentimes low teaching self-efficacy among science teachers (Martin, et al., 2019). Professional development offers an opportunity for teachers to gain confidence through experiencing a real research lab. The current study investigates the outcomes of an extensive 8-week professional development program (N=8) on teachers’ classroom instruction and explores the influential factors in instructional change. Focus groups and individual interviews were conducted to understand teacher’s PD experiences. Three major themes emerged: model the actions of scientists, evidence of inquiry-based instruction, and evidence of self-efficacy. Professional development opportunities including an immersive lab experience, opportunities to build a learning community, and opportunities to feel like a student are influential to changes towards are more inquiry-based learning approach in the classroom and higher self-efficacy. When seeking opportunities for professional development for high school science teachers, school leaders and science teachers should search for key features that promote changes in the classroom leading to more inquiry-based learning.
Prediction of Adenomyosis Diagnosis based on MRI
Authors: Rees Connie , Wiel Marloes van de , Nederend Joost , Huppelschoten Aleida , Mischi Massimo , Vliet Huib van , Schoot Benedictus
Published: August 2022

Study Objective: Development of a prediction tool for histopathological
adenomyosis diagnosis after hysterectomy based on MRI and clinical
parameters. Design: Single-centre retrospective cohort study Setting:
Gynaecological department of a referral hospital from 2007-2022.
Population: 296 women undergoing hysterectomy with preoperative pelvic
MRI Methods: MRI’s were retrospectively assessed for adenomyosis markers
(junctional zone (JZ) parameters, high signal intensity foci (HSI) foci)
in a blinded fashion. A multivariate regression model for
histopathological adenomyosis diagnosis was developed based on MRI and
clinical variables from univariate analysis with p>0.10 and
factors deemed clinically relevant. Results: 131/296 women (44.3%) had
histopathological adenomyosis. Patients were of comparable age at
hysterectomy, BMI and clinical symptoms, p>0.05.
Adenomyosis patients more often had undergone a curettage (22.1% vs.
8.9%, p=0.002), a higher mean JZ thickness (9.40 vs. 8.35mm, p
<.001), maximal JZ thickness (16.00 vs. 13.40mm,
p<.001), mean JZ/myometrium ratio (0.56 vs. 0.49, p=.040), and
JZ differential (8.60 vs. 8.15mm, p=.003). Presence of HSI foci was a
strong predictor for adenomyosis (39.7% vs. 8.9%, p<.001).
Based on the parameters age and BMI, history of curettage,
dysmenorrhoea, abnormal uterine bleeding (AUB), mean JZ, JZ Differential
 5mm, JZ/myometrium ratio >.40, and presence of HSI Foci,
a predictive model was created with a good Area Under the Curve (AUC) of
.776. Conclusions: This is the first study to create a diagnostic tool
based on MRI and clinical parameters for adenomyosis diagnosis. After
sufficient external validation, this model could function as a useful
clinical-decision making tool in women with suspected adenomyosis.
Serum HE4 predicts progestin treatment response in endometrial cancer and atypical hyperplasia: a prospective observational study
Authors: Barr Chloe , Agnew Heather , Bolton James , mcvey rhona , Crosbie Emma
Published: August 2022

Abstract Objective: To investigate serum human epididymis-4 (HE4) as a
predictive biomarker of intrauterine progestin response in endometrial
cancer and atypical endometrial hyperplasia (AEH). Design: Prospective
observational study. Setting: Consecutive sample of women attending a
tertiary gynaecological oncology centre in the North West of England.
Population: Women with AEH or early stage, low grade endometrial cancer
who were unfit or declined primary surgical management; 48 in the
discovery cohort and 28 in the validation cohort. Methods: Women were
treated with a levonorgestrel intrauterine system (LNG-IUS) for 12
months. Endometrial biopsies and imaging were performed to assess
treatment response. Pre-treatment serum HE4 was analysed by
chemiluminescence immunoassay and diagnostic accuracy and logistic
regression analyses performed. Main outcome measure: Progestin response
at 12 months defined by histology and imaging. Results: Baseline serum
HE4 was significantly higher in non-responders than responders in both
discovery [134.6pmol/L (IQR:94.0-292.4) vs 76.5pmol/L (IQR:59.7-87.3),
p<0.001] and validation cohorts [108.2pmol/L
(IQR:80.3-119.2) vs 64.4pmol/L (IQR:53.0-73.0), p=0.004]. An
HE4≥77pmol/L had a sensitivity and specificity for progestin treatment
response of 83.3% and 53.3% in the discovery cohort, and 85.7% and
76.2% and in the validation cohort, respectively. When expressed as a
continuous variable, the AUC was 0.81 (95%CI:0.67-0.95) and 0.87
(95%CI:0.73-1.00) for the discovery and validation cohorts, with every
1pmol/L of HE4 increasing the likelihood of progestin treatment failure
by 2% and 5%, after adjustment for age and histology, respectively
(p=0.02 and p=0.18). Conclusion: Serum HE4 shows promise as a predictive
biomarker of progestin treatment response in endometrial cancer and AEH.
Allometric Equation for Biomass Estimation of Pouteria adolfi-friederici (Engl.) Baehni in Gerba Dima Forest, South western Ethiopia
Authors: Hundie Abyot Dibaba , Soromessa Teshome , Warkineh Bikila
Published: August 2022

Abstract: This study was conducted in Gerba Dima Forest, South Western
Ethiopia to formulate allometric equations for Pouteria
adolfi-friederici. Prior to collecting data for tree allometry, the
study forest was stratified into 3 forest strata based on altitudinal
variation. By employing semi-destructive technique, 30 individuals were
systematically selected and sampled for measuring biomass along the
three forest strata. Based on the data collected, several equations were
developed. Before establishing the allometric equation, scatter plots
were used to see whether the relationship between independent and
dependent variables was linear. Furthermore, several allometric
relationships between independent and dependent variables were tested.
The best-fit model developed was validated by testing the regression
assumptions. AGB was regressed against the various forms of predictors
(i.e., DBH, H and WD) and three allometric models showed significant
performance (p < 0.05) on their F-test. Among the three
allometric equations which showed significant performance, the selection
of the best-fit model was conducted based on their P-value, adjusted r2,
AIC, RMSE. The two models are nested to the third model and hence the
complete model, lnAGB=1.806+1.419×lnDBH+0.628×lnWD, is selected as the
best-fit model against the other two nested models since the p-values of
coefficients of the complete model are significant (p < 0.05).