bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Studies Content Knowledge Interventions for Students With Emotional and Behavioral Disorders: A Meta-Analysis
Authors: Garwood Justin D. , McKenna John W. , Roberts Garrett J. , Ciullo Stephen , Shin Mikyung
Published: March 2019

The importance of social studies and civics education is increasing, as evidenced by the growing number of states requiring coursework in this area for graduation and its growing presence in school accountability frameworks. Social studies instruction is critical for all students so that they may understand their roles, rights, and responsibilities as citizens and how their actions can influence their communities. Students who exhibit antisocial behaviors, such as those with emotional and behavioral disorders (EBD), may especially benefit from social studies and civics education as it promotes college and career readiness and provides opportunities to engage in social problem solving and perspective taking. The purpose of this study was to systematically review the social studies and civics intervention research for students with EBD. We sought to describe and evaluate the extant literature, identify promising practices, and suggest areas for future research. A total of 17 intervention studies were identified. Overall, 10 out of the 17 studies met What Works Clearinghouse Design Standards with or without reservations. Eight of the 10 studies were eligible for effect size calculation, resulting in an overall large effect ( g = 0.83). Study limitations, implications for school practice, and directions for research are discussed.
High-speed Rail Network and Changing Industrial Dynamics in Chinese Regions
Authors: Zhu Shengjun , Wang Chong , He Canfei
Published: March 2019

High-speed railway (HSR) network can significantly reduce the transport cost of people and facilitate interregional knowledge spillovers. It may thus affect regional industrial dynamics. By employing the industrial relatedness indicator, this article shows that regional industrial dynamics is path dependent in China. It further adopts several classical accessibility indicators to capture the network characteristics of transport infrastructure and the accessibility of Chinese cities in the HSR network. In response to the endogeneity issue, we design an instrumental variable based on historic transport network. Another econometric strategy is to include only two groups of cities in the sample: cities with existing HSR stations and cities with planned HSR stations. The empirical results suggest that high accessibility in the HSR network not only pushes forward new industry creation but also enables regions to be more pathbreaking and diversify into less related industries.
Population Geometries of Europe: The Topologies of Data Cubes and Grids
Authors: Grommé Francisca , Ruppert Evelyn
Published: March 2019

The political integration of the European Union (EU) is fragile for many reasons, not least the reassertion of nationalism. That said, if we examine specific practices and infrastructures, a more complicated story emerges. We juxtapose the political fragility of the EU in relation to the ongoing formation of data infrastructures in official statistics that take part in postnational enactments of Europe’s populations and territories. We develop this argument by analyzing transformations in how European populations are enacted through new technological infrastructures that seek to integrate national census data in “cubes” of cross-tabulated social topics and spatial “grids” of maps. In doing so, these infrastructures give meaning to what “is” Europe in ways that are both old and new. Through standardization and harmonization of social and geographical spaces, “old” geometries of organizing and mapping populations are deployed along with “new” topological arrangements that mix and fold categories of population. Furthermore, we consider how grids and cubes are generative of methodological topologies by closing the distances or differences between methods and making their data equivalent. By paying attention to these practices and infrastructures, we examine how they enable reconfiguring what is known and imagined as Europe and how it is governed.
Reification and immaterial production
Authors: Gakis Dimitris
Published: March 2019

Reification, a central theme in radical social/political theory from the 1920s onward, has started falling out of fashion since the 1970s, a period when a number of crucial alterations in the composition of capital and labour start taking place, for example, the tendential hegemony of immaterial/biopolitical labour. The main goal of this article is to discuss reification in light of contemporary changes in the shape of capitalism such as the above. After discussing the relation between reification, alienation and commodity fetishism, I highlight, largely following Hardt and Negri, how reification under the hegemony of immaterial/biopolitical production is, on the one hand, intensified and, on the other hand, (potentially) easier to diagnose, diminish or overcome, due to the increasing emergence of the common as a social relation antagonistic to capital. The article concludes with a note on Wittgenstein and the critique of reification of the symbolic (language) and the ‘inner’ (affects) as the new extended terrain of struggle.
The translation of entrepreneurial intention into start-up behaviour: The moderating role of regional social capital
Authors: Weiss Jan , Anisimova Tatiana , Shirokova Galina
Published: March 2019

This article examines the moderating role of regional social capital in the intention–behaviour link in entrepreneurship. We investigate to what extent the regional social capital context in which aspiring entrepreneurs are embedded strengthens or weakens the translation of individual entrepreneurial intentions into new venture creation activities. Our results suggest that the intention–behaviour link is weakened by cognitive regional social capital in the form of regional hierarchy values and strengthened by structural regional capital in the form of regional cultural diversity and regional breadth of associational activity, as well as by relational regional social capital in the form of high levels of regional generalised trust. Our findings suggest that to support new venture creation activity, there is a need to grow regional social capital via the enhancement of social trust, associational activities and regional cultural diversity – and at the same time decrease hierarchical social structures within regions.
The Consequences of Friend-Related Stress Across Early Adolescence
Authors: Benner Aprile D. , Hou Yang , Jackson Kristina M.
Published: March 2019

The current study investigated early adolescents’ experiences of friend-related stress across middle school and its developmental consequences following the transition to high school. Using a sample of approximately 1,000 middle school students, four unique friend-related stress trajectories were observed across middle school: consistently low friend-related stress (57% of the sample), consistently high friend-related stress (7%), moderate and increasing friend-related stress (22%), and moderate but decreasing friend-related stress (14%). Groups characterized by higher levels of friend-related stress across middle school were linked to subsequent poorer socioemotional well-being, lower academic engagement, and greater involvement in and expectancies around risky behaviors following the transition to high school. Increased friend-related stress across the high school transition was also linked to poorer outcomes, even after taking into account earlier stress trajectories. Gender differences highlighted the particular struggles girls experience both in friend stress and in the links between friend stress and subsequent well-being.
Easy listening? An analysis of infidelity in top pop, hip-hop, and country song lyrics over 25 years
Authors: Alexopoulos Cassandra , Taylor Laramie D.
Published: March 2019

Although it has been established that sexual content is common in popular music, the extent to which this content references cheating behaviors is unclear. Given the prevalence of infidelity among Americans, it is important to examine how infidelity is portrayed in media targeted to young adult listeners. To explore these portrayals, we conducted a content analysis of the 1,500 most popular pop, hip-hop, and country songs in the United States over a 25-year period examining the frequency and nature of infidelity in music. Findings revealed that infidelity was discussed in approximately 15% of popular music, and was most frequently discussed in hip-hop songs. Both negative and positive consequences to infidelity were depicted, and were most often accompanied by a nonchalant emotional tone. Gender portrayals of song characters were consistent with previous research. Implications for young listeners in the context of social relationships are discussed.
On the relevance of music genre-based analysis in research on musical tastes
Authors: Brisson Romain , Bianchi Renzo
Published: March 2019

The investigation of the link between personality and musical tastes has led certain psychology researchers to examine the latent dimensions of musical tastes. In this area of research, investigators have largely relied on genre-based analysis, the relevance of which remains unclear. In this study, we examined the impact of changes in the selection of musical items on the identification of musical taste dimensions. Indeed, investigators have employed heterogeneous sets of music genres in prior research. Such a heterogeneity may partly explain why no clearly reproducible structure of musical tastes has emerged in the literature. Based on principal component analysis, our results indicate that the apparent structure of musical tastes is highly affected by even subtle variations in the items selected. Our findings also suggest that the identified structure of musical tastes strongly depends on the social background and cultural capital of respondents. Finally, our results highlight the limitations of the models that interpret the dimensions of musical tastes in terms of intrinsic musical properties.
Robust Stop-Skipping at the Tactical Planning Stage with Evolutionary Optimization
Authors: Gkiotsalitis Konstantinos
Published: March 2019

The planning of stop-skipping strategies based on the expected travel times of bus trips has a positive effect in practice only if the traffic conditions during the daily operations do not deviate significantly from those expected. For this reason, we propose a non-deterministic approach which considers the uncertainty of trip travel times and provides stop-skipping strategies which are robust to travel-time variations. In more detail, we show how historical travel-time observations can be integrated into a Genetic Algorithm (GA) that tries to compute a robust stop-skipping strategy for all daily trips of a bus line. The proposed mathematical program of robust stop-skipping at the tactical planning stage is solved using the minimax principle, whereas the GA implementation ensures that improved solutions can be obtained even for high-dimensional problems by avoiding the exhaustive exploration of the solution space. The proposed approach is validated with the use of five months of data from a circular bus line in Singapore demonstrating an improved performance of more than 10% in worst-case scenarios which encourages further investigation of the robust stop-skipping strategy.
Noninvasive assessment of blood pressure in rotary blood pump recipients using a novel ultrasonic Doppler method
Authors: Granegger Marcus , Thamsen Bente , Moscato Francesco , Schlöglhofer Thomas , Gross Christoph , Schneider Sarah , Röhrich Michael , Kertzscher Ulrich , Zimpfer Daniel , Affeld Klaus , Schima Heinrich
Published: March 2019

In rotary blood pump recipients with low blood pressure pulsatility, current oscillometric methods to measure blood pressure are not applicable. The aim of this study was to use ultrasonic Doppler flow measurements to determine blood pressure in this patient population noninvasively. In 28 rotary blood pump recipients, blood pressure was measured three times with the developed Doppler method and compared to the invasive arterial line (n = 15) or to the oscillometric Terumo Elemano BP monitor (n = 13). Blood velocities in the radial artery were recorded by the new Doppler sensor during cuff deflation. A sigmoid curve was fitted to a preprocessed velocity signal and the systolic and mean arterial pressures were determined. A total of 84 measurements were performed, and 17 recordings were visually excluded from further analysis due to obvious artifacts. Both the systolic and mean pressures derived by the Doppler method were in good accordance with the invasively measured pressure (3.7 ± 6.6 mmHg for the systolic and −2.1 ± 7.3 mmHg for the mean pressure). A good agreement between the oscillometric monitor and the Doppler method for the systolic (0.0 ± 6.0 mmHg) and mean (1.0 ± 5.9 mmHg) pressures was observed. In this study, a new Doppler blood pressure measurement system was developed and clinically validated. The novel sensor allows easier placement above the radial artery compared to commercial probes. An algorithm was developed which processes the Doppler signal robustly and is able to determine the systolic as well as the mean arterial blood pressure.
Flow rate estimation of a centrifugal blood pump using the passively stabilized eccentric position of a magnetically levitated impeller
Authors: Shida Shuya , Masuzawa Toru , Osa Masahiro
Published: March 2019

Flow rate estimation for ventricular assist devices without additional flow sensors can improve the quality of life of patients. In this article, a novel flow estimation method using the passively stabilized displacement of a magnetically levitated impeller is developed to achieve sufficient accuracy and precision of flow estimation for ventricular assist devices in a simple manner. The magnetically levitated impeller used is axially suspended by a magnetic bearing in a centrifugal blood pump that has been developed by our group. The radial displacement of the impeller, which is restricted by passive stability, can be correlated with the flow rate because the radial hydraulic force on the impeller varies according to the flow rate. To obtain the correlation with various blood viscosities, the relationships between the radial displacements of the magnetically levitated impeller and the pressure head-flow rate characteristics of the pump were determined simultaneously using aqueous solutions of glycerol with a potential blood viscosity range. The measurement results showed that accurate steady flow rates could be estimated with a coefficient of determination of approximately 0.97 and mean absolute error of approximately 0.22 L/min without fluid viscosity measurements by using the relationships between the impeller displacement and the flow rate. Moreover, a precision of approximately 0.01 (L/min)/µm was obtained owing to a strong estimation indicator signal provided by the large displacement of the passively stabilized impeller; thus, the proposed estimation method can help ensure sufficient accuracy and precision for ventricular assist devices in a simple manner, even if the blood viscosity is unknown.
The Ethical Knower: Rethinking Our Pedagogy in the Age of Trump
Authors: Michelson Elana
Published: March 2019

This article seeks to begin a conversation about pedagogical responses to the current moment. Specifically, I argue that two of adult learning’s most venerated practices—transformative learning and the use of personal narrative—are insufficiently nuanced to respond effectively to the political divisions and the epistemological chaos represented by the election of Donald Trump. I ask the adult learning community, first, to revisit the role of culture in our systems for making meaning and deepen our understanding of the relationship between personal identity, community membership, and attitudinal change. I then suggest that our focus on attitudinal change encourages us overlook aspects of our students’ lives out of which a more bracing pedagogy might emerge. I make a case for distinguishing between the hermeneutic self-awareness cultivated in transformative learning and attention to e pistemological ethics as a response to “fake news” and “truthiness.” I argue for a move from Mezirow’s notion of critical self-reflection to Dewey’s positing of reflection as the active and careful consideration of truth claims, a form of reflection that Dewey himself saw as foundational to epistemological integrity.
Usefulness of Cerebral Palsy Curves in Mexican Patients: A Cross-Sectional Study
Authors: Viñals-Labañino Carlos P. , Velazquez-Bustamante Ana E. , Vargas-Santiago Silvia I. , Arenas-Sordo Maria L.
Published: March 2019

Cerebral palsy describes a group of movement and posture disorders that cause activity limitation, and are attributable to nonprogressive disorders that occur in the fetal or infant brain. The growth of these children should not be compared with those of the healthy population. We studied 452 children, 186 female and 266 male. We compared the results in 2 growth charts, Centers for Disease Control and Prevention (CDC) and cerebral palsy, and the results were statistically significant ( P = .00001). With the CDC charts, 40.71% of the patients were below the 5th percentile and only 5.5% of them when we used the charts for cerebral palsy patients. The Mexican cerebral palsy patients were similar to US cerebral palsy patients when we compared height ( P = .4075) and body mass index (BMI) ( P = .4075). Only the weight was found to be different ( P = .00001). All the correlation indexes were negative: Eating and Drinking Ability Classification System (EDACS)-BMI (rho = –0.4798) ( P = .00001), Communication Function Classification System (CFCS)-BMI (rho = –0.4353) ( P = .00001), and Gross Motor Function Classification System (GMFCS)-BMI (rho = –0.3584) ( P = .00001). The growth charts of the healthy pediatric population tend to overestimate the underweight. We propose to use cerebral palsy charts as a reference in our patients. It is possible to determine a functional profile (communication, gross motor function and safety, and feed efficiency) for the cerebral palsy population based on their BMI.
Youth Who Kill in Turkey: A Study on Juvenile Homicide Offenders, Their Offenses, and Their Differences From Violent and Nonviolent Juvenile Delinquents
Authors: Erbay Ayhan , Buker Hasan
Published: March 2019

This study aims to answer two major research questions: (a) What are the characteristics of the juvenile homicide offenders (JHOs) and their offenses in Turkey? (b) How do different risk factors vary across the JHOs and other violent and nonviolent juvenile offenders? The data set was derived from the court records of a group of adjudicated youth ( n = 546) in Turkey. These records were coded to include information on both the offense characteristics of the homicides committed by juveniles (i.e., motivation, weapon of choice, victims’ characteristics, etc.) and the individual and family-level risk factors available in JHOs and two other delinquent groups. Our findings indicated that most of the homicide cases committed by juveniles were motivated by a fight/argument and did not involve any criminal premeditation. The victims were mostly strangers and close in age to the offenders. JHOs were significantly different from other juvenile offenders in a number of aspects, such as age, number of siblings, effectiveness of intrafamilial communication, social mobility, having risky friends, being school dropouts, and working at a paid job. However, JHOs and other juvenile offenders were not significantly different in a majority of the assessed risk factors. The findings pointed out that the risks existing at JHOs were not reflecting the stereotypical perspectives about violent delinquents. For instance, JHOs had the lowest rate of having risky friends compared with other two groups of juvenile offenders. In addition, we found that a typical homicide committed by a juvenile in Turkey was not criminally motivated, in most instances, but the outcome of an instantly escalating personal conflict between youth. In light of the study findings, we proposed several policy implications such as keeping youth in a formal education system to prevent their exposure to culturally inherent adverse social values that promote violent and revengeful reactions to a personal conflict.
Crime Victim Service Providers’ Needs and Barriers: Rurality and “High Need”
Authors: Gillespie Lane Kirkland , King Laura L. , Bostaph Lisa Growette , Goodson Amanda
Published: March 2019

The crime victims’ rights movement has led to the development of advocacy, rights, and services for crime victims. A growing body of research has examined victim service provision using victim/client samples and complementary research has utilized service provider samples. The latter have focused on crime victim service providers’ (VSPs) perceptions regarding clients’ needs and barriers, as well as perceptions of service provision, needs, and barriers pertaining to their agency’s operations. Although relatively small, the body of provider-focused victim services research has commonly considered the influence of rurality on service provision. The present study adds to this body of research by examining reported needs and barriers of VSPs ( N = 94) in a Mountain West state, considering the influence of rurality and concentrated need. Three research questions informed the descriptive analyses: (a) What are the most commonly identified needs and barriers for providers in the state? (b) Are there differences in identified needs and barriers between rural and urban providers? (c) Do certain agencies report more needs and barriers than others, and if so, what are the differences? Findings indicate that many of the needs and barriers identified by VSPs mirror those identified by previous research and that agencies serving rural communities report significantly more needed services than those who do not serve rural communities. Furthermore, approximately 30% of the sample was designated as “high need” due to reported needs and/or barriers exceeding the average of the rest of the sample. The high-need agencies were not exclusively rural in terms of agency location or population served. The potential nuances of rurality’s influence on VSPs in an overwhelmingly rural state are discussed.
The Mediating Role of Distress Tolerance in the Relationship Between Childhood Maltreatment and Mental Health Outcomes Among University Students
Authors: Robinson Martin , Ross Jana , Fletcher Shelley , Burns Carol Rhonda , Lagdon Susan , Armour Cherie
Published: March 2019

A wealth of empirical literature has documented that the experience of childhood maltreatment is related to an increased risk for the development of psychopathologies in adulthood. Empirical studies examining the factors that could possibly explain this relationship, however, remain sparse. The emerging literature on distress tolerance (DT) suggests that it could possibly act as an explanatory or mediating factor within this relationship. The current study, therefore, examined the mediating role of DT in the relationship between childhood maltreatment and psychopathology (posttraumatic stress disorder, depression, anxiety, and alcohol use) in adulthood in a university student population sample ( N = 642). Results showed that childhood maltreatment was positively associated with caseness for all mental health outcomes under investigation. It was also found that individuals with higher levels of DT were less likely to experience adverse mental health outcomes. The results of the mediation analysis indicated that the exposure to childhood maltreatment remained associated with elevated risk for being in the symptomatic group across mental health outcomes, and that DT significantly mediated this relationship. These results provide insight into the relationship between childhood maltreatment and mental ill-health later in life, highlighting the importance of considering DT as a potential risk and resilience factor in this relationship.
Management of Endocrine Emergencies in the ICU
Authors: Jacobi Judith
Published: March 2019

Endocrine emergencies are frequent in critically ill patients and may be the cause of admission or can be secondary to other critical illness. The ability to anticipate endocrine abnormalities such as adrenal excess or , hypothyroidism, can mitigate their duration and severity. Hyperglycemic crisis may trigger hospital and intensive care unit (ICU) admission and may be life threatening. Recognition and safe treatment of severe conditions such as acute adrenal insufficiency, thyroid crisis, and hypoglycemia and hyperglycemic crisis may be lifesaving. Electrolyte abnormalities such as hypercalcemia and hypocalcemia may have underlying endocrine causes, and may be treated differently with recognition of those disorders- electrolyte replacement alone may not be adequate for efficient resolution. Sodium disorders are common in the ICU and are generally related to altered water balance however may be related to pituitary abnormalities in selected patients, and recognition may improve treatment effectiveness and safety.
Association of Parenthood With Incident Heart Disease in United States’ Older Men and Women: A Longitudinal Analysis of Health and Retirement Study Data
Authors: Hipp Sarah L. , Wu Yan Yan , Rosendaal Nicole T. A. , Pirkle Catherine M.
Published: March 2019

Objective: To examine the association of number of children birthed/fathered with incident heart disease, accounting for socioeconomic and lifestyle characteristics. Methods: We analyzed data from 24,923 adults 50 and older (55% women) in the Health and Retirement Study. Participants self-reported number of children and doctor-diagnosed incident heart disease. Cox proportional hazards models estimated heart disease risk. Results: Compared to women with one to two children, those with five or more had increased risk of heart disease (hazard ratio [HR] = 1.13, 95% confidence interval [CI] = [1.03, 1.25]). Compared to men with one to two children, those with five or more had a marginally increased risk of heart disease (HR = 1.11, 95% CI = [0.99, 1.25]), but this association attenuated in models adjusting for socioeconomic and lifestyle variables. Compared to men with no children, those with five or more retained a borderline significant association in the fully adjusted model (HR = 1.15, 95% CI = [0.99, 1.35]). Discussion: Social and lifestyle pathways appear to link parenthood to cardiovascular health.
Refinement of the two-color pyrometry method for application in a direct injection diesel and natural gas compression-ignition engine
Authors: Khosravi Mahdiar , Kirchen Patrick
Published: March 2019

The soot emissions from internal combustion engines have significant health and environmental impacts and, as such, are subject to increasingly stringent regulations. Two-color pyrometry provides the in-cylinder soot cloud temperature and soot volume fraction and can provide insight to the in-cylinder soot formation and oxidation processes to guide research for reducing engine-out soot emissions. This work demonstrates improvements to the two-color pyrometry methodology, with a focus on low-temperature, low-soot regimes such as low-temperature combustion or combustion of direct injected natural gas. Through selection of a fast and robust numerical algorithm, characterizing and increasing the detection envelope, performing static and dynamic perspective adjustments, accounting for non-uniform and non-linear system response, as well as localized signal-to-noise ratio enhancement through image filtering, the performance of the pyrometric method was improved by a 40% increase in the resolved signal fraction. The refined two-color method was evaluated for both direct injected diesel and natural gas fueling strategies using a pilot-ignited direct injected natural gas fuel system and facilitated evaluation of local temperatures and soot concentrations in pilot-ignited direct injected natural gas combustion, despite the generally low soot levels in this combustion strategy.
Derivation of road noise improvement factor within a suspension system using the inverse substructuring method
Authors: Kang Yeon June , Kim Jun Gu , Song David P , Ih Kang Duck
Published: March 2019

This research aims to develop a method to efficiently reduce the body input force from the chassis due to road-induced excitation. To this end, the frequency response function–based substructuring method is employed to model the vehicle cross member and coupling points. Using this model, the dynamic stiffness modification factor of elastic bushing at the effective path is predicted for reducing road noise. Because of the difficulties in directly obtaining dynamic properties of body mount bushings pressured into the sub-frame, the frequency response function–based substructuring model and inverse formulation method are used to indirectly estimate the bushing’s dynamic properties. Therefore, the primary focus of this study is to validate the feasibility of using the inverse formulation method for deriving road noise improvement factor on a simple cross member application. In this feasibility validation, road excitation is simply substituted with a shaker excitation in vertical direction. The previously developed suspension rig that enables a direct measurement of the body input force at the coupling points and the specially developed cross member jig are used for the validation test.
The effect of crack geometry on non-destructive fault detection of EN 8 and EN 47 cracked cantilever beam
Authors: Khalkar V , Ramachandran S
Published: March 2019

Since long it has been observed that the size of the crack in structures increases with time, and finally, it may lead to its catastrophic failure. Hence, it is crucial to do the vibration study of cracked structures with regard to vibration-based crack detection and the classification of cracks. So far, vibration-based non-destructive testing method is applied to many spring steel cracked cantilever beams for its possible crack detection. However, the effect of various kinds of practical cracks, that is, V-shaped and U-shaped, on the applicability of these methods has been overlooked. To investigate this issue, artificially cracks are made on the cantilever beam. By free vibration analysis, the effect of crack geometry, crack depth, and crack location on natural frequency is investigated. The natural frequency results obtained from V-shaped and U-shaped models for the same crack configurations are compared with each other and it is revealed that the results are not much sensitive for the change of crack geometry. Hence, it is clear that free vibration-based crack detection method approximately predicts the crack parameters, that is, crack location and crack depth, in structures irrespective of the crack geometry. It is also found that for the same configuration, results of natural frequency are comparatively on the lower side for U-shaped crack models than V-shaped crack models. In this study, the natural frequency of each cracked case is computed by a theoretical method and numerical method and shows good agreement. Finally, it is also observed that structural integrity of a cracked cantilever beam is a function of crack location.
Global union federations and international framework agreements: Knowledge exchange and creation
Authors: Barreau Jocelyne , Havard Christelle , Bah Angélique Ngaha
Published: March 2019

International Framework Agreements negotiated between Global Union Federations and multinational companies are a major innovation which bring collective bargaining to an international level. We focus on the role of the union negotiators and analyse two cases, drawing on studies of innovation processes in business organizations. We identify types of learning processes and the exchange and creation of knowledge, and examine relations inside international trade union networks. We find that two conditions are necessary to develop an innovatory role: international unions must coordinate exchanges between different communities, holders and creators of specific union knowledge, and must also facilitate the dissemination of knowledge by maintaining the regularity and quality of exchanges between network members.
Onset of the African Humid Period by 13.9 kyr BP at Kabua Gorge, Turkana Basin, Kenya
Authors: Beck Catherine C , Feibel Craig S , Wright James D , Mortlock Richard A
Published: March 2019

The shift toward wetter climatic conditions during the African Humid Period (AHP) transformed previously marginal habitats into environments conducive to human exploitation. The Turkana Basin provides critical evidence for a dynamic climate throughout the AHP (~15–5 kyr BP), as Lake Turkana rose ~100 m multiple times to overflow through an outlet to the Nile drainage system. New data from West Turkana outcrops of the late-Pleistocene to early-Holocene Galana Boi Formation complement and extend previously established lake-level curves. Three lacustrine highstand sequences, characterized by laminated silty clays with ostracods and molluscs, were identified and dated using AMS radiocarbon on molluscs and charcoal. This study records the earliest evidence from the Turkana Basin for the onset of AHP by at least 13.9 kyr BP. In addition, a depositional hiatus corresponds to the Younger Dryas (YD), reflecting the Turkana Basin’s response to global climatic forcing. The record from Kabua Gorge holds additional significance as it characterized the time period leading up to Holocene climatic stability. This study contributes to the paleoclimatic context of the AHP and YD during which significant human adaptation and cultural change occurred.
Holocene paleoecological changes and agro-pastoral impact on the La Narce du Béage mire (Massif Central, France)
Authors: Dendievel André-Marie , Dietre Benjamin , Cubizolle Hervé , Hajdas Irka , Kofler Werner , Oberlin Christine , Haas Jean Nicolas
Published: March 2019

A paleoecological study (macrofossils, pollen, cryptogam spores, non-pollen palynomorphs) was performed to investigate environmental changes recorded on the peat deposits of the La Narce du Béage mire (Massif Central, France). We reconstructed the development of a limnogenous mire ecosystem during the Holocene, consequently to the infilling of a small Late Glacial lake. Successions from aquatic flora ( Isoëtes, Nitella opaca/ syncarpa, Botryococcus, Alisma plantago-aquatica, Potamogeton, Sparganium) to mire plant species ( Alnus glutinosa, Betula nana, Betula pubescens, Cyperaceae, Ericaceae, Sphagnum) underlined a gradual eutrophication and acidification during the lowering of the water table. We demonstrated a clear link between these local hydro-ecological changes and the early Holocene climatic warming. Also dealing with archeology, we provided key issues for the identification of human-induced environmental changes. Three phases of ecological disturbances with clearings of the mixed-oak forest and agro-pastoral activities were evidenced at 7700–7300, 6800–6420, and 5500–4250 cal. BP. Our results confirmed early Neolithic (Cardial influences), middle Neolithic (Chassean), and late Neolithic (Ferrières group) frequentations of the Béage Plateau, probably included in large-scale socio-cultural changes (SE France, NW Mediterranean Basin). Later, forest clearings (beech and fir), cultivation, and pastoralism were outlined since the Iron Age (after 2300 cal. BP, that is, 350 BC). Increasing human pressure was especially recorded during the last 1700 years, with rye ( Secale cereale) cultivation and extensive livestock grazing around and on the mire, which is nowadays a protected ‘Natura 2000’ area.
Fluvial response to rising levels of the Black Sea and to climate changes during the Holocene: Luminescence geochronology of the Sakarya terraces
Authors: Erturaç Mehmet Korhan , Şahiner Eren , Zabcı Cengiz , Okur Hilal , Polymeris Georgios S , Meriç Niyazi , İkiel Cercis
Published: March 2019

The Sakarya River is among the largest fluvial systems of the southern Black Sea basin, draining most of NW Anatolia. The river crosses the high relief of the Pontide mountain range through successive narrow gorges and strike-slip basins formed by the North Anatolian Fault (NAF) System. We have investigated this fluvial record along the course of the main river channel at its lower reaches. The study site is located south of the Adapazarı Basin, ~50 km inland from the Black Sea, where remnant floodplains are preserved as a three-step terrace staircase resulting from continuous uplift to the south of the NAF. The combination of high resolution mapping with a detailed luminescence (OSL and p-IR-IRSL) and radiocarbon geochronology has shed light on changes in the level of the Black Sea and in the hydrological system during the late Pleistocene to recent. The last glacial period is represented by the highest terrace (T3) indicating deposition during marine isotope stage (MIS) 3 in between two low stands of the Black Sea. Following a long-term erosional period initiated prior to last glacial maximum (LGM), the initiation of the deposition (T2) was synchronous with the proposed catastrophic sea level rise of the Black Sea (cal. C14 9.3 ka BP) which continued throughout the Holocene until the Roman warm period (1.8 ka BP). The late-Holocene to recent morphological evolution of the region is marked with two sequential erosional and depositional (T1 and T0) periods, which can be correlated with the well-documented historical climate shifts affecting the hydrological system. These results reveal that the erosional and depositional periods on the Sakarya River floodplain are controlled by major sea level changes and climatically induced fluctuations in discharge and sediment supply.
Changes in cerebral glucose metabolism after acupuncture at KI3 in spontaneously hypertensive rats: a positron emission tomography study
Authors: Li Jing , Peng Chong , Lai Dongjian , He Kejie , Wang Yumei , Zhang Gaochuan , Wu Yuwen , Nie Binbin , Shan Baoci , Tang Chunzhi , Lai Xinsheng
Published: March 2019

Objective:

The aim of this study was to explore the effect of acupuncture stimulation at KI3 on brain glucose metabolism in spontaneously hypertensive rats (SHRs).

Methods:

Brain glucose metabolism in SHRs after acupuncture stimulation at KI3 was detected using 18F-2-fluorodeoxy-D-glucose positron emission tomography (18F-FDG-PET). SHRs were randomly divided into three groups: no treatment (SHR group); acupuncture at KI3 (KI3 group); and sham acupuncture (Sham group). Wistar Kyoto (WKY) rats were used as a normal blood pressure (BP) control group. Rats were subjected to 10 min of acupuncture once a day for 7 days. BP and positron emission tomography–computed tomography (PET-CT) were measured after the first acupuncture session and after 7 days of treatment.

Results:

The results showed that BP was lower in the KI3 group than in the SHR group, both 30–60 min after the first acupuncture session and 24–48 h after the 7-day treatment. Compared with the WKY group, the SHR group had lower glucose metabolism in the motor cortex, sensory cortex, basal ganglia, corpus callosum, caudate putamen, and visual cortex. Compared with the untreated/sham-treated SHR control groups, cerebral glucose metabolism was lower in the medulla oblongata, thalamus, dorsal thalamus, orbital cortex, and hypothalamus after acupuncture at KI3, while it was higher in the olfactory cortex and inferior phrenic muscle.

Conclusion:

Our results show that, in SHRs, needling at KI3 reduces high BP, most likely by altering the activation of cerebral regions.
Assessment of the CoaguChek-XS portable prothrombin time point-of-care analyzer for horses
Authors: Berlin Noa , Kelmer Efrat , Segev Gilad , Aroch Itamar , Kelmer Gal
Published: March 2019

Coagulopathies in horses are common and potentially life-threatening. In equine field medicine, a portable point-of-care (POC) prothrombin time (PT) testing device could be useful to identify early changes in extrinsic clotting. The CoaguChek-XS (Roche Diagnostics) is a small, portable POC PT analyzer used in human medicine. Our preliminary study assessed the suitability of CoaguChek-XS for testing PT in horses and established the PT reference interval (PT RI) in healthy horses using this instrument. Blood samples collected from 102 healthy and ill horses were analyzed with the CoaguChek-XS and compared to a semi-automated coagulometric analyzer (SACA) as the gold standard. There was a significant positive correlation between the 2 measurement methods ( r = 0.765, p < 0.01), and very good agreement, with 97% of the samples falling within limits of agreement. The mean CoaguChek-XS PT coefficient of variation was 0.8%, indicating high precision. With high precision and good agreement with the coagulometric PT, the CoaguChek-XS should be further validated for PT measurement in horses.
Quantitation of neonicotinoid insecticides, plus qualitative screening for other xenobiotics, in small-mass avian tissue samples using UHPLC high-resolution mass spectrometry
Authors: Filigenzi Michael S. , Graves Emily E. , Tell Lisa A. , Jelks Karen A. , Poppenga Robert H.
Published: March 2019

We developed and validated a liquid chromatography–high-resolution mass spectrometry (LC-HRMS) analytical method for quantitatively measuring pesticide concentrations in small-body avian tissue samples using homogenized 1–2-d-old chicken carcasses as the test matrix. We quantified the following key insecticides: sulfoxaflor (sulfoximine class) and the neonicotinoids dinotefuran, nitenpyram, thiamethoxam, acetamiprid, thiacloprid, clothianidin, and imidacloprid. We used fortified chick carcass samples to validate method accuracy (80–125% recoveries), precision (<20% relative standard deviation), and sensitivity (≤1.2 ppb) for these targeted analytes. This method also uses full-scan, high-resolution MS to screen for the presence of a wide variety of other xenobiotics in bird carcasses. The utility of our screening process was demonstrated by the detection of carbaryl in some samples. This sensitive LC-HRMS analytical method for insecticide detection in a matrix of homogenized carcass is ideal for evaluating small birds for insecticide exposure. This novel whole-carcass method may allow for research studies of small-bodied, free-ranging avian species, and could provide insight regarding their exposure to multiple classes of environmental contaminants.
Meconium aspiration pneumonia and otitis media in two goat kids
Authors: Newman Shelley J. , Fasina Olufemi O.
Published: March 2019

We report meconium aspiration in 2 sibling goat kids, and characterize the expected lesions of aspiration pneumonia in conjunction with the rare lesion of otitis media. Grossly, the lungs were multifocally consolidated, and there was yellow-green exudate within the middle ear. Histologically, the lung was characterized by pyogranulomatous pneumonia and foreign-body reaction around aspirated debris. Within the lumen of the middle ear, aspirated squamous cells, keratin, meconium debris, and neutrophils, without evidence of bacteria, were accompanied by a subepithelial accumulation of lymphocytes, plasma cells, and fewer macrophages. This is an especially rare phenomenon, which is thought to result from transport of meconium from the oropharynx through the auditory tube (Eustachian tube) to the middle ear.
An outbreak of Mycoplasma mycoides subspecies capri arthritis in young goats: a case study
Authors: Johnson Gayle C. , Fales William H. , Shoemake Brian M. , Adkins Pamela R. , Middleton John R. , Williams Fred , Zinn Mike , Mitchell W. Jeff , Calcutt Michael J.
Published: March 2019

Mycoplasmosis is a well-known cause of morbidity and mortality in small ruminants. Previously recognized outbreaks have involved arthritis, and pneumonia or pleuropneumonia. Modern bacteriology procedures rely less on isolation techniques that require special media for mollicutes given that these species are notoriously difficult to isolate, and rely more on PCR tests. We report an outbreak of arthritis, pleuropneumonia, and mild meningitis affecting dairy goat kids, spanning a period of 3 y, which had unusual epidemiologic characteristics related to husbandry practices. Lesions were characterized by polyarthritis of the appendicular joints, with copious joint fluid and extension of arthritic exudate beyond the joint itself. The cause remained unknown until serendipitous isolation of a mycoplasma on blood agar. Mycoplasmosis was not detected from synovial samples by a general mycoplasma PCR, despite multiple attempts. Isolated colonies were also negative by this general PCR assay. The isolate was identified as Mycoplasma mycoides subspecies capri, using universal 16S primers and amplicon sequencing. Testing of additional isolates from other diseased goats in the herd confirmed that this was the cause of illness. A failure to recognize the distinct nature of organisms of the M. mycoides group of mycoplasmas meant that a PCR test that cannot detect this group of organisms was utilized at first, and the etiology of the illness was overlooked for a period of time. Veterinary pathologists and microbiologists must be aware of the limitations of some PCR assays when confronted with joint disease and pleuropneumonia in small ruminants.
Disassociation of Spa type and serovar of an Erysipelothrix rhusiopathiae serovar 6 strain isolated from a diseased pig
Authors: Shimoji Yoshihiro , Bito Makiko , Shiraiwa Kazumasa , Ogawa Yohsuke , Nishikawa Sayaka , Eguchi Masahiro
Published: March 2019

The surface protective antigen (Spa) protein of Erysipelothrix rhusiopathiae is an important component in protecting pigs against swine erysipelas. The Spa protein has been antigenically divided into 3 types: SpaA, SpaB, and SpaC. Swine erysipelas vaccines are formulated with strains of serovar 1 and/or 2, both of which are SpaA-possessing serovars. The association of Spa type with E. rhusiopathiae serovar has been reported, and therefore, the determination of the Spa type and the serovar of clinical isolates are important to assess vaccine efficacy. An E. rhusiopathiae strain, designated Ireland, was isolated from a diseased pig and identified as serovar 6 by a conventional agar gel precipitation test. Sequence analysis of the chromosomal locus presumably defining the serovar antigenicity of E. rhusiopathiae revealed that the gene content and organization of the chromosomal regions of the Ireland strain were identical to those of the serovar 6 reference strain (Tuzok). Sequence analysis of the spa gene and dot blots using a SpaA-specific monoclonal antibody confirmed that, unlike the Tuzok strain possessing SpaB, the Ireland strain expressed SpaA, indicating that the Spa type is not associated with the serovar in this strain. Thus, further investigation into the association between Spa type and serovar of clinical swine isolates is warranted.
Nonoperative Orthodontic Therapy for Retrognathia and Finding of Sella Turcica Bridging in a 16-Year-Old Girl With Freeman-Burian Syndrome
Authors: Olkun Hatice K. , Poling Mikaela I.
Published: March 2019

In the context of a case presentation of a 16-year-old girl treated for retrognathia associated with Freeman-Burian syndrome (FBS), importance of early orthodontic evaluation and unique problems posed by FBS are discussed. Freeman-Burian syndrome universally presents limited oral access and risk of pulmonary complications, making immaculate oral health-care arduous but mandatory. With early identification and conscientious planning, satisfactory orthodontic and overall health outcomes can be achieved. Sella turcica bridging, when presenting in FBS in the absence of endocrine pathology, may be related to the underlying myopathy of FBS.