bluuebunny/crossref_metadata_2025 huggingface dataset:
La politique des petits nombres : Comment appréhender l’histoire de la statistique vaccinale et de ses effets ?
Authors: Thomas Gaëtan
Published: January 2025

Les débats suscités par la diffusion de l’inoculation en Europe, au XVIIIe siècle, ont alimenté des pages glorieuses de l’histoire du calcul de probabilités. Ce procédé ancien, courant en Orient et en Extrême-Orient, qui préfigura l’invention de la vaccine à la fin du XVIIIe siècle, consistait à̀ administrer à un sujet sain de la substance prélevée sur les vésicules d’un malade de la variole. La technique n’était pas sans danger pour la personne inoculée. Des savants européens se mirent à calculer des risques comparés de mourir de la variole ou de l’inoculation. Mais déjà, pour reprendre une distinction proposée par Alain Desrosières, la statistique n’était pas qu’une affaire de preuve, elle relevait du gouvernement de la population. C’est la raison pour laquelle Michel Foucault a fait du contrôle de la variole au XVIIIe siècle un exemple emblématique de ses réflexions sur la biopolitique.
Food-Derived Tripeptide–Copper Self-Healing Hydrogel for Infected Wound Healing
Authors: Chen Han , Yang Pu , Xue Ping , Li Songjie , Dan Xin , Li Yang , Lei Lanjie , Fan Xing
Published: January 2025

The field of infected wound management continues to face challenges, and traditional methods used to cope with wounds include debridement, gauze coverage, medication, and others. Currently, synthetic and natural biomaterials are readily available today, enabling the creation of new wound dressings that substantially enhance wound healing. Considerable attention is being paid to hydrogels based on natural materials, which have good biocompatibility and degradability properties, while exhibiting higher similarity to natural extracellular matrix as compared to synthetic materials. In this study, we extracted the active ingredients of oxidized konjac glucomannan (OKGM) and fresh egg white (EW) from 2 foods, konjac, and egg, respectively, and formed a self-repairing hydrogel based on the cross-linking of a Schiff base. Subsequently, a natural active peptide, glycyl-
l
-histidyl-
l
-lysine-Cu (GHK-Cu), was loaded, and an all-natural composite hydrogel dressing, EW/OKGM@GHK-Cu (GEK), was developed. The GEK hydrogel, exhibiting both antibacterial and anti-inflammatory properties, plays a hemostatic role by adhering to tissues and promoting neovascularization and serves as an optimal dressing for skin regeneration. Taken together, GEK hydrogel dressings derived from natural food sources therefore constitute an efficient and cost-effective strategy for managing infected wound healing and have significant potential for clinical application and transformation.
مفهوم الفيء وتطور دلالاته في عصر النبوة والخلفاء الراشدين
Authors: Al-Momani Mohammad Khaled
Published: January 2025

الأهداف: هدفت الدراسة الحالية إلى التعرض إلى مفهوم الفيء في اللغة والاصطلاح، وتطور معناه النظري والتطبيقي في عصر النبوة والخلفاء الراشدين، كما هدفت الدراسة التطرق للتطبيقات العملية لمفهوم الفيء الذي صحبه بعض الاجتهادات والمستجدات والاستثناءات في عصر النبوة والخلفاء الراشدين.
المنهجية: استخدمت الدراسة المنهج التحليلي من جمع المعلومات بطريقة الاستقصاء استناداً إلى الآيات القرآنية الكريمة، والسنة النبوية الشريفة، والروايات التاريخية المتضمنة ما وقع من أحداث في عصر النبوة والخلفاء الراشدين، التي تميزت بالجهاد وبدء الفتوحات الإسلامية، ثم فهمها، وفرزها، وتصنيفها، وتحليلها بما يتوافق مع الفترة الزمنية من جهة، وكيفية تطبيقها عملياً من جهة ثانية، واستخراج النتائج.
النتائج: أشارت النتائج إلى أنّ مفهوم الفيء ما عاد ورجع لأيدي المسلمين من الكفار صلحاً أم عنوة من أراضٍ وأموال وممتلكات وغيرها. كما أشارت النتائج أن تطور مفهوم الفيء جاء وفق الاجتهادات في دلالته بحسب الفترة الزمنية، فقد جاء بمعنى الغنيمة، والجزية، الخراج، كما جاء بمعنى الجزية والخراج معاً كما شمل الجزية والخراج وعشور التجارة  والصواف. كما خلصت النتائح أن الرسول محمد- صلى الله عليه وسلم- اجتهد في تطبيقه لمفهوم الفيء وفقاً للسياسة الشرعية التي تعود بالمنفعة على المسلمين، وتبعه أبو بكر- رضي الله عنه- في ذات النهج، إلا أن الخليفتين عمر بن الخطاب، وعثمان بن عفان رضي الله عنهما؛ تعاملا مع الفيء بوقف الأرض، وتزويد بيت المال المسلمين بريعها.
الخلاصة: إنَّ التوضيح الدلالي والتطوري لمفهوم الفيء لمعناه وفقاً للمستجدات المتعلقة في اختلاف الزمان والمكان في عصر النبوة والخلفاء الراشدين من الجانبين النظري والعملي، يزيل اللبس في تطبيقه في ضوء الظروف والمستجدات والمرحلة الزمنية المرتبطة بهما.
ОСОБЕННОСТИ ВЫПАДЕНИЯ СИЛЬНЫХ ОСАДКОВ В ТЕПЛЫЙ ПЕРИОД ГОДА В ПЕРМСКОМ КРАЕ
Authors: Поморцева Анна Александровна , Пьянков Сергей Васильевич
Published: January 2025

Проведено исследование повторяемости осадков теплого периода, проанализирована средняя интенсивность осадков по метеорологическим станциям в Пермском крае, оценено влияние рельефа местности на количество и интенсивность выпадающих осадков, проанализирована частота выпадения сильных осадков за период 2011-2020 гг. В исследовании теплый период года определен временным интервалом с мая по октябрь включительно, так как в это время на всей территории Пермского края выпадают осадки в виде дождя. Преобладающим видом осадков являются обложные дожди слабой и сильной интенсивности. Наибольшее число дней с осадками в течение теплого периода отмечается в октябре (до 25), наименьшее - в мае (14 случаев). В течение всего периода на юге Пермского края (метеостанция Чернушка) отмечается минимальное число дней с дождями. Максимальное число дней зафиксировано на метеостанциях Верещагино и Кудымкар. При этом на метеостанции Верещагино в разные годы отмечен как минимум (2012 г.), так и максимум (2019 г.) дождливых дней. Сильные осадки регистрируются на всей территории края в среднем в течение 40 дней за теплый период; несколько чаще они отмечаются на горной станции Бисер (восток Пермского края).

The paper studies the frequency of precipitation during the warm period, analyzes the average precipitation intensity at meteorological stations in the Perm region, assesses the influence of the terrain on the amount and intensity of precipitation, and analyzes the frequency of heavy precipitation for the period 2011-2020. In the study, the warm period of the year is defined as a time interval from May to October inclusive, since at this time precipitation falls in the form of rain throughout the Perm Krai. The predominant type of precipitation is continuous rains of weak and heavy intensity. The largest number of days with precipitation during the warm period is observed in October (up to 25), the smallest - in May (14 cases). During the entire period, in the south of the Perm Krai (weather station Chernushka), there is a minimum number of days with rain. The maximum number of days was recorded at the Vereshchagino and Kudymkar weather stations. At the same time, the Vereshchagino weather station in different years recorded both a minimum (2012) and a maximum (2019) of rainy days. Heavy precipitation is recorded throughout the territory of the region on average for 40 days during the warm period; somewhat more often they are noted at the Biser mountain station (east of the Perm Territory).
A Comparative Study of Audience Experience in Traditional and Interactive Movie
Authors:   Xiamen Academy of Arts and Design, FuZhou University, Xiamen, China, Lin Yuying , Chu Yuejun ,   Xiamen Academy of Arts and Design, FuZhou University, Xiamen, China
Published: January 2025

Traditional movie offers audiences a "movie myth" experience through the comprehensive use of sound, light, and electricity and realistic narratives.With the advancement of scientific levels and the emergence of new media, movie art has derived more forms and content.Interactive movie is considered a new form of movie with its interaction and participation with audiences as its characteristics, providing a different audience experience from traditional movie. This article focuses on the dimension of audience experience, compares the narrative structure, emotional mode, and interactive form of traditional movie and interactive movie for research purposes, analyzes the different experiences of audiences when watching traditional movie and interactive movie, explores the core audience experiences.It inspires moviemakers to reflect on their work in order to optimize and enhance the audience experience with interactive movies by creating better interactive movie works that provide narrative references in terms of emotion as well as interactivity.
Animated Interactive Communication of the Chinese Zodiac through Virtual Reality Technology
Authors:   College of Arts and Design, Jimei University, Xiamen 361021, China, Zhou Hongbin , Jean Ming-Der ,   College of Arts and Design, Jimei University, Xiamen 361021, China;, Li Jiahao ,   College of Arts and Design, Jimei University, Xiamen 361021, China, Lu Ke ,   College of Arts and Design, Jimei University, Xiamen 361021, China;
Published: January 2025

This study aims to explore the impact of a combination of virtual reality (VR) technology and Chinese zodiac animation for the dissemination of Chinese zodiac culture. A questionnaire survey was conducted for 100 university teachers and students for their experience in the VR Chinese zodiac animation. We used Flash, 3DMax, and UNITY to design a virtual showroom animation. Participants were highly satisfied with the VR Chinese zodiac animation with Cronbach's alpha coefficients of 0.862 and 0.941, confirming the internal consistency and reliability of the results. This animation provides an interactive experience, immersive viewing, and a space for imagination. The experts’ understanding of VR technology and Chinese zodiac animation was higher than that of the students. The combination of VR technology and Chinese zodiac animation enhances communication and the user experience of Chinese zodiac culture. The results of this study are important for the design and improvement of VR for Chinese zodiac animations.
PROJECT FINANCING AND ITS ROLE IN THE REVITALIZATION OF INFRASTRUCTURE DAMAGED OR DESTROYED BY WAR
Authors: SHULIUK Bohdana
Published: January 2025

Introduction. The need for post-war reconstruction and further development of the country increases the interest in summarising foreign experience of using project finance and assessing the possibilities of its application in Ukraine, taking into account the strategic priorities of the state, its national characteristics and global challenges. The urgency of its implementation is heightened by the growing scale of damage and destruction of infrastructure against the backdrop of a permanent budget deficit, which necessitates the creation of favorable legislative, institutional, informational and financial conditions for attracting investment.

The purpose of the article is to summarise scientific approaches to disclosing the essence and characteristics of project financing, and to determine the prospects for using its sources in the process of revitalizing infrastructure facilities damaged and destroyed by the full-scale invasion of Ukraine by the Russian aggressor.

Results. The article highlights the content of the concept of “project financing” and identifies its inherent features, including: the creation of a special project company, the presence of a large number of participants, the proportional distribution of risks and profits among all stakeholders, and the use of a wide range of financial instruments. The author investigates the dynamics of project financing sources in the regions of the world based on the data of analytical agencies “IJ Global” and “Thomson Reuters”. The expediency of project financing for the revitalization of infrastructure facilities is substantiated, given the significant scale of destruction caused by hostilities in Ukraine. Attention is focused on the reasons that impede the effective implementation of revitalization measures. The algorithm for forming a strategy for the revitalization of war-damaged and destroyed infrastructure facilities with the involvement of project financing sources for the implementation of socially important projects, determining the forms and conditions of interaction between participants is outlined.

Conclusions. The research found that the most effective financial form of infrastructure restoration is project financing, which allows for the implementation of capital-intensive projects with minimal financial participation of its initiators. The success of revitalization depends on the legislative and institutional conditions created to attract a wide range of sources of project financing – bank loans, project bonds, investments from international financial institutions and businesses. The basis for the implementation of these tasks should be the National (Regional) Strategy for the revitalization of infrastructure damaged and destroyed by war, which will help to outline the vectors of Ukraine's reconstruction.
INNOVATIVE RESERVES OF URBAN DEVELOPMENT: CONCEPTUAL FOUNDATIONS
Authors: KRYSOVATYY Ihor
Published: January 2025

Introduction. In today’s changing conditions, as well as under the influence of digitalization and globalization, the question of urbanization and the formation of urbanism is gaining more and more importance as a science that investigates the complex relationships between cities, their population and the environment. Innovative reserves of urban development are key to ensuring the sustainable growth of cities, improving the quality of life of their residents, and optimizing the use of resources. Management and financial aspects of these innovations are integral components of the process, because they determine the effectiveness of the implementation of new solutions and technologies.

The purpose of the article is to determine the main innovative reserves of urban development and analyze its managerial and financial aspects.

Results. In the presented study, the essence of the concept of "innovative reserve of development" is clarified, the essence of urban planning as a modern phenomenon of urban development is characterized. Features of management and financial aspects of urban development are determined. A scientific-theoretical approach to the definition of innovative reserves for the development of modern urban planning, taking into account financial and managerial aspects, is proposed. Conclusions. Thus, the study of innovative reserves of urban development in the managerial and financial context is extremely relevant and requires a comprehensive approach that will contribute to the sustainable development of cities and the improvement of the lives of their residents.

The management aspect includes the development of strategies that allow for the integration of innovations into urban infrastructure and services, which involves not only the adaptation of new technologies, but also the active participation of the community in decision-making, which, in turn, promotes social cohesion.

The financial aspect, in turn, concerns investments in the development of the urban environment, the involvement of private partners and the use of innovative financial instruments. In this context, a balance between public and private funding is important, which will allow the implementation of ambitious projects with maximum benefit for the community.
TANAMAN OBAT SEBAGAI WARISAN BUDAYA: STUDI MIXED METHODS
Authors: Zakiyah Zahrah , Febriati Listia Dwi , Puspita Dewi Devillya
Published: January 2025

Latar belakang: Indonesia merupakan negara dengan keberagaman hayati yang tinggi. Pemerintah terus berupaya melestarikan penggunaan tanaman obat tradisional dengan berbagai program peningkatan kualitas pemanfaatan tanaman obat dalam bentuk obat tradisional terstandar dan fitofarmaka yang telah teruji secara ilmiah. Tujuan: : menggali lebih dalam tentang faktor yang mendorong pemanfaatan tanaman obat oleh masyarakat melalui pendekatan ilmiah berbasis kuantitatif dan kualitatif. Metode : Metode penelitian menggunakan metode campuran (mixed methods) dengan desain sequential explanatory. Tahap pertama menggunakan metode kuantitatif quasi experimental dengan desain the one-group pretest-posttest design dan analisis data wilcoxon signed rank test, selanjutnya metode kualitatif dilakukan pada tahap kedua dengan model Miles dan Huberman. Metode kualitatif digunakan untuk memperdalam dan memperluas data analisis kuantitatif. Hasil: Ada perbedaan bermakna rerata pengetahuan responden sebelum dan sesudah penyuluhan manfaat tanaman obat diberikan (p-value=0,000) dan 83.33% jawaban informan yang menyatakan berminat memanfaatkan tanaman obat.  Kesimpulan: Pengetahuan yang baik dapat mendorong minat masyarakat memanfaatkan tanaman obat sebagai warisan budaya untuk meningkatkan kesehatan secara rutin dalam kehidupan sehari-hari.
IMPLEMENTASI MODUL PENDAMPINGAN KELUARGA BAGI TIM PENDAMPING KELUARGA DI TINGKAT KALURAHAN SEBAGAI UPAYA PENURUNAN STUNTING
Authors: Indrayani Novi , Casnuri Casnuri , Maratusholikhah Nurtyas Maratusholikhah , Oktaviani Fransiska Sela
Published: January 2025

Latar belakang: Indonesia saat ini dihadapkan pada masalah kesehatan yang mengancam yaitu stunting. Saat ini fokus pemerintah dalam penanganan stunting antara lain melalui intervensi gizi spesifik dan gizi sensitif. Intervensi gizi spesifik dilakukan oleh tenaga kesehatan profesional dan memiliki kontribusi sekitar 30% dalam pencegahan stunting. Jumlah baduta di Kalurahan Wedomartani sebanyak 58 baduta. Dari 58 baduta terdapat 18 baduta berisiko stunting dan 2 orang ibu hamil. Kalurahan Wedomartani merupakan salah satu kalurahan yang telah menjalankan program pendampingan keluarga dengan risiko stunting. Namun, pelaksanaan pendampingan terhadap keluarga risiko stunting belum maksimal. Tujuan: Penelitian ini bertujuan untuk mengetahui Implementasi Modul Pendampingan Keluarga Bagi Tim Pendamping Keluarga Di Tingkat Kalurahan Sebagai Upaya Penurunan Stunting. Metode : Penelitian Ini merupakan penelitian deskriptif dengan pendekatan kualitatif yang bertujuan menganalisis serta mendeskripsikan fenomena yang diteliti. Teknik yang digunakan dalam penelitian ini yaitu wawancara. Hasil: Penyusunan modul petunjuk penggunaan harus lebih terperinci sehingga lebih mudah untuk digunakan. Kesimpulan: Modul pelatihan bagi Tim Pendamping Keluarga dapat dijadikan acuan dalam pelaksanaan pendampingan pada keluarga dengan risiko stunting sebagai upaya mempercepat penurunan stunting di tingkat kalurahan.
PENGARUH PEMBERIAN SARI KACANG HIJAU TERHADAP PENINGKATAN KADAR HEMOGLOBIN PADA REMAJA PUTRI ANEMIA
Authors: Mualifah Nita Azimatul , Sunarsih Tri , Yulaikhah Lily
Published: January 2025

Latar belakang: Remaja putri menghadapi peningkatan kerentanan terhadap anemia karena pertumbuhan fisik yang cepat dan permulaan menstruasi pada tahap ini. Akibatnya, remaja putri memerlukan zat gizi dalam jumlah yang lebih tinggi, terutama zat besi, sehingga mereka sangat rentan terhadap anemia. Untuk mengatasi kekurangan zat besi ini, seseorang dapat melengkapi pola makannya dengan makanan kaya zat besi, seperti kacang hijau, yang mengandung 13,96 mg/L zat besi dalam setiap 100 gramnya. Tujuan: Penelitian ini bertujuan untuk mengetahui dampak pemberian jus kacang hijau terhadap peningkatan kadar hemoglobin pada remaja putri anemia yang berada di MAN 1 Kulonprogo. Metode :  Penelitian ini menggunakan desain quasi eksperimen dengan Pretest – Posttest Control Group Design. Penelitian difokuskan pada populasi remaja putri yang bersekolah di MAN 1 Kulon Progo. Sampel penelitian berjumlah 20 orang yang dipilih dengan menggunakan teknik purposive sampling dan dibagi menjadi dua kelompok. Intervensi diberikan selama 7 hari. Penelitian dilaksanakan di MAN 1 Kulon Progo. Data diperiksa dengan uji beda berpasangan (paired sample t-test). Hasil: Kadar hemoglobin pada kelompok intervensi mengalami peningkatan dari 11,05±0,79 menjadi 12,03±0,98 gr/dl setelah diberikan jus kacang hijau. Kelompok kontrol memiliki rata-rata konsentrasi hemoglobin 11,25±0,42 gr/dl sebelum pengujian dan sedikit menurun menjadi 11,20±0,62 gr/dl setelah pengujian. kelompok intervensi menunjukkan pengaruh yang signifikan terhadap kadar hemoglobin sebelum dan sesudah menerima jus kacang hijau (p=0,025), yang mengindikasikan perubahan yang berarti pada tingkat hemoglobin setelah intervensi. Kesimpulan: pemberian jus kacang hijau memberikan dampak positif terhadap peningkatan kadar hemoglobin pada remaja putri anemia.
FAKTOR PENYEBAB KETIDAKAKURATAN KODE ICD-10 KASUS OBSTETRY
Authors: Efendi Bahtiar , Wulandari Ayu , Umami Siti Fithrotul
Published: January 2025

Latar belakang: Klasifikasi Statistik Internasional tentang Penyakit dan Masalah Kesehatan Terkait (ICD-10) dapat menjadi tidak akurat jika diagnosis medis salah. terdapat perbedaan kode dengan kasus penyakit lainnya, sehingga seringkali terjadi kesalahan saat menggunakannya. Kesalahan semacam ini dapat mempengaruhi pengelolaan informasi kesehatan yang tepat. Tujuan: Penelitian ini bertujuan untuk melakukan studi tentang hubungan antara ketepatan penulisan diagnosa dan keakuratan kode ICD-10 dengan kasus persalinan Metode :  Penelitian berjenis analitik korelasi, dengan pendekatan retrospektif. Variabel pada penelitian ini yakni ketepatan penulisan diagnosa serta keakuratan koding pada kasus obstetry. Penelitian ini memanfaatkan data primer yang dikumpulkan melalui observasi dokumen rekam medis. Analisis yang diterapkan mencakup analisis univariat dan bivariat, dengan menggunakan uji chi-square untuk mengevaluasi hubungan antara ketepatan penulisan diagnosis dan keakuratan pengkodean. Hasil: 46,2% ketepatan penulisan diagnosa diperoleh. Berdasarkan hasil uji chi-square didapatkan p-value 0,002 yang menginterpretasikan terdapat hubungan antara ketepatan penulisan diagnosa dengan keakuratan kode ICD-10 kasus obstetry. Kesimpulan: Ketidaktepatan penulisan diagnosa dapat mengakibatkan tidak akuratnya kode ICD-10.
KECANDUAN GADGET DENGAN MASALAH EMOSI DAN PERILAKU PADA REMAJA
Authors: Afdalia Faizah , Sundari Ririn Isma , Arni Nur Rahmawati Arni Nur
Published: January 2025

Latar belakang: Gadget adalah salah satu jenis kemajuan teknologi yang sangat disukai. Remaja yang kecanduan perangkat elektronik akan asik dengan diri mereka sendiri, mengabaikan lingkungan sekitar, jam tidur, dan menurunkan prestasi akademik di sekolah. Tujuan: Untuk mengetahui hubungan antara kecanduan gadget dengan masalah emosi dan perilaku pada remaja di MAN 1 Banyumas Tahun 2024. Metode :  Metode penelitian yang digunakan pada penelitian ini adalah desain analitik dengan metode pendekatan cross-sectional. Sampel pada penelitian ini berjumlah 230 responden diambil dengan cara teknik proportionate random sampling. Instrument pada penelitian ini menggunakan kuesioner yaitu kuesioner Smartphone Addiction Scale – Short Version (SAS-SV) dan kuesioner Strength and Difficulties Questionnaire (SDQ). Hasil: responden dengan mayoritas kecanduan gadget dengan kategori berat sebanyak 126 responden (54,8%) sedangkan responden dengan mayoritas masalah emosi dan perilaku normal sebanyak 113 responden (49,1%). Kesimpulan: terdapat hubungan antara kecanduan gadget dengan masalah emosi dan perilaku pada remaja di MAN 1 Banyumas.
BODY IMAGE DENGAN KEPERCAYAAN DIRI PADA REMAJA PUTRI
Authors: Fajrianti Gustin , Sundari Ririn Isma , Apriliyani Ita
Published: January 2025

Latar belakang: Remaja mengalami perkembangan dan perubahan pada body image dan kepercayaan diri. Tujuan: Penelitian ini bertujuan untuk mengetahui bagaimana hubungan antara body image dengan kepercayaan diri remaja putri. Metode :  jenis penelitian kuantitatif. Desain penelitian yang digunakan adalah survei analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini berjumlah 340 siswi kelas X. Teknik pengambilan sampel menggunakan proportionate stratified random sampling dengan sampel sebanyak 184 responden. Hasil: Remaja putri di MAN 1 Banyumas sebagian besar responden berusia 16 tahun sebanyak 132 responden (71,7%). Kategori body image positif sebanyak 100 responden (54,3%), 159 responden (86,4%) memiliki tingkat kepercayaan diri tinggi. Uji korelasi Rank Spearman didapatkan nilai p 0,000<0,05 dengan nilai koefisien korelasi sebesar 0,273 yang artinya terdapat hubungan positif antara body image dengan tingkat kepercayaan diri pada remaja putri Kesimpulan: Body image dengan kepercayaan diri berhubungan maka semakin positif body image seseorang, semakin tinggi kepercayaan dirinya.
Improvement of MoS2 film quality using sputtering processes controlling particle- and energy-flux followed by sulfur-vapor annealing
Authors: Imai Shinya , Tatsumi Tetsuya , Tomiya Shigetaka , Kakushima Kuniyuki , Wakabayashi Hitoshi
Published: January 2025

Molybdenum disulfide (MoS2) deposited by sputtering holds promise for applications in areas such as three-dimensional (3D)-stacked field-effect transistors (FETs) and human-interface devices. The quality of the MoS2 film is enhanced by maintaining a low particle flux with sufficient energy flux during sputtering. Furthermore, the sulfur defects in the MoS2 films were suppressed by annealing in a sulfur-vapor atmosphere, leading to an improvement in the film quality. This technology has great potential for the development of high-performance FETs based on MoS2 channels using sputtering.
Implementasi Sistem Pengendalian Manajemen Berbasis Prinsip Good Corporate Governance untuk Meningkatkan Kinerja Pelayanan Publik pada Kantor Dispendukcapil Kota Surabaya
Authors: Utami Yekti , Soeherman Bonnie
Published: January 2025

Tujuan dari penelitian ini adalah untuk menganalisis implementasi sistem pengendalian manajemen berbasis prinsip good corporate governance untuk meningkatan kinerja pelayanan publik pada Kantor Dispendukcapil Kota Surabaya. Penelitian ini dilakukan di Kantor Dispendukcapil yang beralamat di Jl. Tunjungan No.1-3, Genteng, Kec. Genteng, Surabaya, Jawa Timur. Penelitian direncanakan selama 3 (tiga) bulan mulai bulan Mei sampai dengan bulan Juli 2024. Jenis pendekatan pada penelitian ini adalah pendekatan kualitatif deskriptif. Teknik pengumpulan data adalah wawancara. Setelah mengumpulkan data pada tahapan di atas, tahapan dalam teknik pengolahan data kualitatif menurut Miles and Huberman. Kesimpulan dari penelitian ini adalah dalam menerapkan Prinsip Good Corporate Governance yang terdiri dari nilai-nilai transparansi, akuntabilitas, tanggung jawab, kemandirian, kewajaran, dan kesetaraan ini, Kantor Dispendukcapil di Kota Surabaya dapat meningkatkan kinerja pelayanannya dengan memberikan layanan yang lebih responsif, efisien, adil, dan setara bagi semua masyarakat. Transparansi dalam prosedur dan kebijakan memberikan akses yang mudah bagi masyarakat, sementara akuntabilitas memastikan bahwa setiap tindakan atau keputusan dapat dipertanggungjawabkan. Tanggung jawab pegawai dan kemandirian Kantor Dispendukcapil di Kota Surabaya memastikan integritas dan efisiensi dalam pelayanan, sementara kewajaran dan kesetaraan memastikan bahwa setiap individu diperlakukan dengan adil tanpa diskriminasi. Dengan menerapkan nilai-nilai ini secara konsisten, Kantor Dispendukcapil di Kota Surabaya dapat meningkatkan kepercayaan masyarakat dan memberikan pelayanan yang lebih responsif, efisien, dan berkualitas.
Strategi Pemasaran dalam Penerapan Digital Marketing pada Kewirausahaan UMKM Kuliner: Studi Kasus pada “Bakso dan Mie Ayam Mami Inung” di Rajabasa, Bandar Lampung
Authors: Daud Syahril , Maxentia Cindy , Paolo Clarissa Chandra , Tanuhardja Ferdinand
Published: January 2025

Technological advances have brought significant changes in the business world, especially through digital marketing which provides great opportunities for UMKM to increase revenue and competitiveness. This research aims to analyze the digital marketing strategies implemented by UMKM “Bakso and Mie Ayam Mami Inung” in Bandar Lampung, with a focus on optimizing social media and e-commerce platforms. This research uses a qualitative approach with descriptive methods, involving in-depth interviews, participatory observation, and document analysis. The results show that digital marketing strategies such as the utilization of social media, delivery platforms, and collaboration with influencers can increase product visibility and accessibility. However, challenges such as lack of digital skills and fierce competition are still major obstacles. SWOT analysis identified a great opportunity in utilizing technology to reach a wider market. Implementation of strategies such as creative content creation, discount promotions, and marketing data analysis are recommended to improve business sustainability. This research provides insights for other UMKM in developing effective digital marketing strategies to improve competitiveness in the digital era.
Pengaruh Demografi Terhadap Foreign Direct Investmen di Negara Asia Selatan
Authors: H. Masri Zainal Arifin , Alam Bambang Perkasa , Barkah Januar
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi pengaruh factor demografi terhadap investasi langsung asing (FDI) di negara-negara India, Pakistan dan Bangladesh.  Melalui data dan literature terkait, kami mengidentifikasi bahwa faktor demografi seperti jumlah penduduk berpenghasilan rendah, anak-anak penderita stunting dan penduduk berpendidikan rendah dapat memiliki dampak signifikan terhadap aliran FDI. Penelitian ini memberikan wawasan yang berharga bagi pengambil keputusan bagi pemerintah dan investor untuk memahami dinamika investasi di negara India, Pakistan dan Banglades.  Penelitian ini menggunakan metode kuantitatif. Data FDI, penduduk berpenghasilan rendah, anak-anak penderita stunting dan penduduk berpendidikan rendah untuk India, Pakistan dan Bangladesh diperoleh dari bank dunia.  Kurun waktu yang digunakan 2015 sampai dengan 2021.  Hasil penelitian diperoleh secara simultan penduduk berpenghasilan rendah, anak-anak penderita stunting dan penduduk berpendidikan rendah berpengaruh signifikan terhadap pertumbuhan ekonomi, hal ini ditunjukkan dengan probabilitas (F-statistik) 0,000000 lebih kecil dari 0,05. Secara individual penduduk berpenghasilan rendah berpengaruh signifikan terhadap pertumbuhan ekonomi, hal ini ditunjukkan dengan probabilitas 0,0000 lebih kecil dari 0,05. Sedangkan anak-anak dibawah umur 5 tahun penderita stunting tidak berpengaruh terhadap pertumbuhan ekonomi, hal ini ditunjukkan dengan probabilitas 0,6023 lebih besar dari 0,05. Demikian juga dengan penduduk berpendidikan rendah tidak berpengaruh terhadap pertumbuahan ekonomi, hal ini ditunjukkan dengan probabilitas 0,0646 lebih besar dari 0,05.
Prediksi Nilai Unburned Carbon Batubara yang Dihasilkan PLTU Menggunakan Algoritma Linear Regression, Random Forest, dan LightGBM Regression
Authors: Syarif Muhyiddin , Afiyati
Published: January 2025

Penelitian ini berfokus pada prediksi tingkat karbon yang tidak terbakar di pembangkit listrik berbahan bakar batu bara untuk meningkatkan efisiensi operasional. Prediksi yang akurat terhadap karbon yang tidak terbakar sangat penting karena berdampak langsung pada efisiensi pembakaran bahan bakar dan keberlanjutan lingkungan. Penelitian ini membandingkan tiga algoritma machine learning: Linear Regression, Random Forest, dan LightGBM Regression, menggunakan metrik performa seperti Mean Absolute Error (MAE), Mean Absolute Percentage Error (MAPE), dan Root Mean Squared Error (RMSE). Hasil menunjukkan bahwa LightGBM Regression memiliki performa terbaik dengan MAE sebesar 0,31, MAPE sebesar 1,29, dan RMSE sebesar 0,38, mengungguli kedua model lainnya. Model ini dapat dioptimalkan lebih lanjut untuk meningkatkan akurasi prediksi, sehingga berkontribusi pada operasi pembangkit yang lebih efisien dan ramah lingkungan. Penerapan machine learning dalam penelitian ini mendukung pengambilan keputusan berbasis data di sektor energi.
A Novel Encoder Decoder Architecture with Vision Transformer for Medical Image Segmentation
Authors: Saroj Bala  , Kumud Arora  , R Jeevitha , Rini Chowdhury  , Prashant Kumar  , C.Shobana Nageswari
Published: January 2025

Brain tumor image segmentation is one of the most critical tasks in medical imaging for diagnosis, treatment planning, and prognosis. Traditional methods for brain tumor image segmentation are mostly based on Convolution Neural Network (CNN), which have been proved very powerful but still have limitations to effectively capture long-range dependencies and complex spatial hierarchies in MRI images. Variability in the shape, size, and location of tumors may affect the performance and may get stuck into suboptimal outcomes. In these regards, new encoder-decoder architecture with the VisionTranscoder(ViT) is proposed, to enhance brain tumor detection and classification. The proposed VisionTranscoder exploits a transformer's ability in modeling global context through self-attention mechanisms, providing more inclusive interpretation of the intricate patterns in medical images and classification by capturing both local and global features. The proposed VisionTranscoder maintains the Vision Transformer in its encoder for processing images as sequences of patches to capture global dependencies often outside the view of traditional CNNs. Then the segmentation map is rebuilt at a high level of fidelity with the decoder through upsampling and skips connections to maintain detailed spatial information. The risk of overfitting is hugely reduced by design and advanced regularization techniques with extensive data augmentation. The dataset contains 7,023 human brain MRI images, all of which are in four different classes: glioma, meningioma, no tumor, and pituitary. Images from the 'no tumor' class, indicating an MRI scan without any detectable tumor, were taken from the Br35H dataset . The results show the efficiency of VisionTranscoder over a wide set of brain MRI scans, producing an accuracy of 98.5% with a loss of 0.05. This performance underlines the ability of it to accurately segment and classify a brain tumor without overfitting.
Veränderung des intrathorakalen Blutvolumens und der Oxidationspotentiale bei Apnoesportlern unter hyperbaren Bedingungen
Authors: Schedler Olaf , Schedler Olaf , Dix Enrico , von Rottkay Eberhard , Leunert Karsten
Published: January 2025

In einem Casereport wird der Einfluss von Überdruck und Sauerstoff während einer hyperbaren Exposition auf das intrathorakale Blutvolumen (ITBV) und auf den oxidativen Stress an einem freiwilligen Probanden gemessen. Mit zunehmenden Überdruck reduziert sich das ITBV um 100 ml/bar. Das Herzzeitvolumen nimmt um 1L/min/bar ab. Das extravaskuläre Lungenwasser (EVLW) steigt um 15 ml/bar an. Durch einer hyperbaren Oxygenation erhöht sich die totale antioxidative Kapazität exponentiell um 30 µmol/l/bar, wobei keine Erhöhung des oxidativen Stress (TOS) wahrzunehmen ist.
Dynamische Telemedizin in der Seefahrt
Authors: Schedler Olaf
Published: January 2025

Defibrillatoren in Seefahrt mit halbautomatsicher Datenübertragung an eine ärztlich besetzte Konsilstelle können den Einsatz dieser medizintechnsichen Geräte verbessern und Sicherheit in der Behandlung von Seeleuten vermitteln. Der dafür hinterlegte Algorithmus muss 3 sichere Möglichkeiten zur Diagnose ermöglichen. Asystolie, Rhythmusstörungen, Normalbefund.
Propofol TIVA versus TCI zur Anästhesie bei Patienten mit Myasthenia gravis.
Authors: Schedelr Olaf , Grebe Dirk , Werner Jörg , Böttger Joachim , Gellert Klaus
Published: January 2025

Die Myasthenia gravis (MG) ist eine Autoimmunerkrankung mit der Bildung von Autoantikörper gegen nikotinerge postsynaptische Acetylcholinrezeptoren der motorischen Endplatte. Die Inzidenz der MG liegt insgesamt bei 3-4:1.000.000. Die Prävalenz wird mit 60-100 pro 1.000.00 Personen angegeben. Neben den primären Acetylcholinrezeptor Antikörper kommen Rezeptorfunktionsstörungen durch die Arzneimittelinteraktionen an der neuromuskulären Übertragungsstörung während der Anästhesie in Frage. Die unkomplizierte Propofolanwendung konnte in Einzelfällen in der Literatur aufgezeigt werden.
Comparative oxygen saturation measurements in hypobaric conditions.
Authors: Schedler Olaf , Günther Oliver
Published: January 2025

The diagnosis and therapy altitude-related diseases essentially depends on the determination of peripheral arterial oxygen saturation (SpO2). While up to 11% of height exposed individuals develop pulmonary edema (HAPE, high altitude pulmonary edema), have 53% of all mountain travelers from 3500 meters above sea level, symptoms of acute mountain sickness (AMS, acute mountain sickness) on [1,2]. Crucial to the development of AMS and HAPE is the decrease of the alveolar oxygen partial pressure due to height-related barometric pressure reduction. It made two determinations of peripheral arterial oxygen saturation of 14 participants during a Elbrusexpedition (5642 meters). Due to weather conditions only at an altitude of 5218 meters was reached. The initial height was 2400 meters. Intermediates were in 3040, 3265, 3580 and 4075 meters. The average determined arterial oxygen saturation was by Nonin Onyx 89.7 Â± 5.68%, and was significantly different (p <0.05) of the ascertained with SET SpO2 of 91.1 Â± 5.60%. The pulse rate was not significantly different (p> 0.05). She was with Nonin Onyx 89.2 Â± 17.4 beats per minute compared with the SET oximetry of 97.1 Â± 19.1 / min. In the corresponding altitude regions arose in
Validation of an oxygen-wash in/wash out technique for determination of FRC
Authors: Schedler Olaf
Published: January 2025

The routine determination of the functional residual capacity (FRC) was to assess the progress and to monitor therapeutic procedures to ventilated patients benefit. It was measured by means LUFU FRC (LUFU FRC) in 20 healthy volunteers when sitting or lying, and in 15 lung disease patients in a sitting position with the determined by helium dilution FRC (He-FRC) and with the determined by body plethysmography intrathoracic gas volume (ITGV ) compared. In each case four LUFU FRC values (FiO2 change of 0.21 to 0.5 and back to 0.21 and from 0.21 to 1.0 and back to 0.21) and two He-FRC and two were ITGV values bestimmt.Bei the volunteers had mean LUFU FRC sitting at 3.26 L, the He-FRC sitting at 3.11 L and 3.08 L ITGV in while the values lying on 2.29 L in LUFU FRC and 2.00 L reduced in the He-FRC. The correlation between LUFU FRC and FRC He gave a sitting R2 of 0.84 and lying a R2 of 0.80. Average arose for sitting and lying measurements a correlation of R2 = 0.87. Between LUFU FRC and ITGV was the correlation R2 = 0.81 and was between He-FRC and ITGV the R2 = 0.82. The comparison of the FiO 2 of 0.29 and 0.79 in the LUFU FRC showed together for lying and sitting position a correlation of R2 = 0.96. From the comparison of the determined by Sauerstoffeinatmung and Sauerstoffauswaschung average FRC an R2 = 0.95 resulted. The comparison of the first and second measurement revealed in all methods of determination from 0.74 to 0.96.
Das System der räumlichen Orientierung in der Schwerelosigkeit
Authors: Jähn Sigmund , Schedler Olaf
Published: January 2025

Der Einfluss der Schwerelosigkeit (SL) auf das System der räumlichen Orientierung erfolgt sowohl unmittelbar in Form der Beendigung der Einwirkung der Schwerkraft auf die gravitationsabhängigen Strukturen als auch durch die Veränderung des Charakters der Bewegungsabläufe in der SL selbst. Das Fehlen der Wirkung der Schwerkraft beeinflusst in erster Linie das Otolithensystem des Vestibularapparates, welches für die Wahrnehmung von linearen Beschleunigungen bei Bewegungen des Kopfes verantwortlich ist. In der SL wird eine Neigung des Kopfes als eine Drehung registriert, aber die Otolithen nehmen die Neigung des Kopfes nicht wahr. Das ruft einen sogenannten sensorischen Konflikt hervor.
Physiologische Prinzipien der Laser-Doppler-Flowmetrie und der Weißlichtspektrometrie – O2 to See (O2S) zur Messung der Mirkorzirkulation.
Authors: Schedler Olaf
Published: January 2025

Die Mikrozirkulation umfasst alle Gefäße mit einem Durchmesser <150 µm und beinhaltet als Gefäßabschnitt das Gebiet des Stoffaustausches zwischen der terminalen Strombahn und den Geweben. Die terminale Strombahn umfasst Arteriolen, Kapillaren, Venolen und die terminalen Lymphgefäße. Die kontraktilen Eigenschaften des Kapillargebietes werden maßgeblich durch das Vorhandensein von glatten Muskelzellen in der Media Schicht der Gefäße gesehen, welcher in den Arterien 33,5% und in den kleinen Venen einen Anteil von 60,5% aufweisen. Mit einem hohen Anteil von glatten Muskelzellen (smooth muscle cells-SMC) und einem geringen Anteil von Kollagen wird die geringe Druckbelastung des kapillaren Gefäßnetzes zum Ausdruck gebracht und durch die Abnahme der Druckgradienten im Kapillargebiete ist der Anteil des Elastins gering. Die regionale Sauerstoffsättigung gilt als Maß für die Sauerstoffausschöpfung im lokalen Gewebe und somit für den Funktionszustand der lokalen Mikrozirkulation und Marker für eine lokale Gewebehypoxie. Eine Änderung des rSO2-Wertes kann eine Dysbalance zwischen Sauerstoffangebot und Sauerstoffverbrauch widerspiegeln und korreliert mit dem zellulären Sauerstoffmetabolismus. Der relative Blutflow bestimmt den Volumenfluss und kann Auskunft über das Vorliegen einer Ischämie oder einer Hyperämie geben. Darüber hinaus kann die Geschwindigkeitsverteilung der Erythrozyten einen Hinweis auf eine mögliche Ursache einer Minderversorgung der Mikrozirkulation geben. Mit der relativen Blutflussgeschwindigkeit wird die Durchschnittsgeschwindigkeit der Erythrozyten in der Mikrozirkulation angegeben. Die relative Hämoglobinmenge zeigt die Hämoglobinmenge im gemessenen Gewebe an. Sie kann eine Auskunft über den Füllzustand der Gefäße der Mikrozirkulation, welche abhängig ist von Kapillardichte, dem Kapillarrecruitment und venöser Füllung ist, geben. Die Hämoglobinmenge ist der Indikator für den venösen Status und die Sauerstoffextraktion.
Time series analysis of dengue incidence in Bandung City, Indonesia using a ARIMA model
Authors: Sutriyawan Agung , Martini Martini , Sutiningsih Dwi , Agushybana Farid , Wahyuningsih Nur Endah , Adamu Victor Eneojo , Akbar Hairil , Aba Matheus
Published: January 2025

Background. Dengue is a public health problem that leads to death. This disease is necessary to monitor to reduce its impact on the community.
Purpose. This study aims to forecast the incidence of dengue in Bandung City using historical data from 2014 to 2023.
Method. This retrospective observational study examined dengue incidence in Bandung City from 2014 to 2023, secondary data were processed and analysed using Autoregressive Integrated Moving Average (ARIMA) model to forecast dengue incidence.
Results. The best model generated is ARIMA (3,0,3), Mean Absolute Percentage Error (MAPE = 33,3437) and Akaike Information Criterion (AIC = 0,1489). Based on the model, the peak of dengue cases is estimated to occur in September 2024 (320 cases).
Conclusion. The peak incidence of dengue in Bandung City will occur in September 2024. Hence the need for vector control efforts in several sub-districts and increasing efforts to prevent and control dengue.
Analysis of antibiotic sensitivity of clinical strains of microorganisms with the Russian Mueller–Hinton broth
Authors: Kosilova Irina S. , Domotenko Lyubov V. , Khramov Mikhail V.
Published: January 2025

Introduction. One of the reasons for spreading antibiotic-resistant microorganisms is the uncontrolled use and inadequate empirical prescription of antibiotics which is not based on the results of the pathogen sensitivity testing. The broth dilution method and one of its implementation options, the reference microdilution method, in contrast to the disk diffusion method, allows testing virtually all pathogen-antibiotic combinations. To realize the method, a production technology of Russian Mueller–Hinton broth (MHB-Obolensk) has been developed under the import substitution program.
The aim. To evaluate the quality of the developed domestic Mueller–Hinton broth in comparative tests with its imported analog BD BBL (MHB-BD) in testing clinical strains of microorganisms, including microorganism–antibiotic combinations pairs which cannot be reliably investigated by the disc diffusion method.
Materials and methods. The study investigated the sensitivity of 47 clinical strains of Gram-positive and Gram-negative bacteria to antibiotics of various functional groups using the broth microdilution method with MHB-Obolensk and MHB-BD.
Results. The MICs values of antibiotics for clinical strains obtained with the developed and control media did not practically differ from each other or differed by +/– one dilution. The difference by two two-fold dilutions was noted when testing Enterococcus faecium–ampicillin, Klebsiella pneumoniae–meropenem, Pseudomonas aeruginosa–levofloxacin and Staphylococcus aureus–ciprofloxacin combinations. For the first two combinations, the MIC values were lower in MHB-Obolensk, and for the last two, they were higher than in MHB-BD. The differences obtained did not affect the clinical categories of sensitivity.
Conclusion. The antibiograms of clinical strains in developed Russian Mueller–Hinton broth was obtained, which did not differ from those for the comparison medium. MHB-Obolensk complies with the requirements of national and international standards and can be used to reliably test, among other things, current combinations of microorganism–antibiotic pairs that cannot be studied using the disk diffusion method.
A clinical study of the immunogenicity and protective potency of a live recombinant GamLPV vaccine for intranasal use for the prevention of whooping cough in adult volunteers
Authors: Lidzhieva Alevtina A. , Medkova Alisa Yu. , Kulikov Sergey V. , Sinyashina Ludmila N. , Sioundioukova Rezida A. , Markov Andrey P. , Verveda Aleksey B. , Abaeva Natalia E. , Chernyshova Irina N. , Gavrilova Marina V. , Bushkova Kristina K. , Dyakov Ilya N. , Karataev Gennady I.
Published: January 2025

Introduction. The increase in incidence rate of pertussis worldwide, short-term insufficient immunity induced by acellular pertussis vaccines (TDaP) and their failure to provide antibacterial protection and to prevent transmission of infection in human population dictate the development of new pertussis vaccines. A new live recombinant pertussis vaccine for intranasal use (GamLPV) has completed preclinical studies in experiments on nonhuman primates and 2 phases of clinical trials involving adult healthy volunteers, in which the safety, immunogenicity and protective activity of the GamLPV were proven. Method and scheme of vaccine administration have been worked out.
Aim. Confirmation of the immunogenicity and protective antibacterial potency of GamLPV in a randomized multicenter clinical trial on adult volunteers.
Materials and methods. In this multicenter, clinical, randomized, placebo-controlled, double-blind study 260 healthy adults aged 18–65 years were divided into 2 groups: G1 — 210 volunteers (GamLPV) and G2 — 50 volunteers (placebo). 0.25 ml GamLPV delivered to each nostril (5 × 109 CFU) 60 days apart. Levels of Bordetella pertussis-specific IgG, IgA antibodies in blood serum and levels of B. pertussis-specific secretory IgA antibodies in nasopharyngeal aspirates were measured by ELISA method and agglutination test. The dynamics of elimination of attenuated B. pertussis bacteria after the first and second intranasal administration of GamLPV to volunteers was estimated by using qPCR.
Results. Significant seroconversion of B. pertussis-specific IgG and IgA antibodies and growth of B. pertussis-specific secretory IgA antibody levels in nasal aspirates of volunteers were demonstrated. The dynamics of changes in the levels of IgG and IgA antibodies indicates a booster effect after second vaccination. Attenuated B. pertussis bacteria persist in the nose/oropharynx of vaccinated volunteers. The period of elimination after second vaccination is more than 2 times shorter than the period after the first one. The number of persistent B. pertussis bacteria after the second vaccination is less than 3% of the values after the first vaccination.
Conclusion. High immunogenicity and the formation of antibacterial protection after single and double intranasal vaccination of GamLPV have been proven.