bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of the dynamic properties of chaotic circuits in the presence of memristors
Authors: Kareem Zainab Shiaa , Husseini Hussein B. Al
Published: March 2024

This paper first discusses a memristor model based on a multi-segment linear function with three different circuits. Then, based on the different values of the parameters of the memristors introduced, the dynamic behavior of these circuits is analyzed in terms of bifurcations, coexisting attractors, and complexity. Bifurcation analysis reveals the rich dynamic behavior of these circuits, including period-doubling bifurcations, bursts of chaos, and transients of chaos. The Muthuswamy exhibit dynamic phenomena including coexisting attractors, multistability, and super multistability under different initial conditions. Moreover, circuit simulation is used to confirm the existence and feasibility of the Chua circuit. Coexisting attractor’s generation circuits that can alter the initial values of arbitrary state variables are designed. The advantages of the proposed system are illustrated by comparisons with other chaotic attractors, which include controllable attracter number and direction, straightforward implementation circuits, and rich dynamic behavior. Lastly, the Colpitts circuit, which contains the BTJ transistor and becomes steadier when a memristor is substituted for it, as well as the coexistence of multiple chaotic attractors, end up being more stable. Simulation results indicate that the three proposed circuit schemes in this paper require less time to achieve complete dynamics than other circuit schemes. This feature improves the suggested circuit strategy's effectiveness and usability in practical applications.
Examining the combined effect of antenatal care visits and iron-folic acid supplementation on low birth weight: A pooled analysis of two national data sets from Nepal
Authors: Khanal Vishnu , Bista Sangita , Lee Andy H
Published: March 2024

Introduction: The prevalence of low birth weight (LBW) has remained constant at approximately 12% for the past 15 years in Nepal, significantly impacting newborn survival. While antenatal care (ANC) visits and iron-folic acid supplementation are recognized as essential for reducing LBW, there is lack ofevidence regarding their combined effect. This study aimed to explore the potential synergistic impact of ANC and iron-folic acid supplementation on LBW in Nepal by analyzing data pooled from two national surveys.
Methods: The nationally representative Nepal Demographic and Health Surveys of 2016 and 2022 were used, and the pooled dataset was analyzed. Birth weight and the prevalence of LBW were reported using descriptive statistics. The associations between LBW, ANC visits, and iron-folic acid supplementation were examined using logistic regression analyses.
Results: The mean birth weight was 3011g, with an LBW prevalence of 11.2%. Not attending ANC (Adjusted Odds Ratio (AOR): 1.49; 95% Confidence Interval (CI): 1.15, 1.95) and not consuming iron-folic acid supplement (AOR 1.44; 95% CI: 1.12, 1.85) were independently associated with a higher likelihood of LBW. Jointly, mothers who attended less than four ANC visits and consumed iron-folic acid ≤90 days (AOR: 1.90; 95% CI: 1.37, 2.61) had the highest risk of giving birth to LBW infants after controlling for key confounding factors.
Conclusion: Combining ANC visits and iron-folic acid supplementation appeared to have more impact than administering either intervention alone in reducing LBW births in Nepal.
Evaluating Organic Fertilizers and Microbial Inoculation for Soilless and Hydroponic Crop Production
Authors: McClintic Nicklas , Chen Zhihao , Park Yujin
Published: March 2024

Because hydroponic operations in the United States can be certified as organic, and because the price of chemical fertilizers has increased, there is an increasing interest in using organic fertilizers and beneficial microorganisms for controlled-environment agriculture. However, there is a scarcity of information regarding their effectiveness and application methodologies. We investigated the effects of inoculating Azospirillum brasilense and Rhizophagus intraradices and using organic fertilizers on growing lettuce (Lactuca sativa ‘Cherokee’) and tomato (Solanum lycopersicum ‘Red Robin’) young plants in an indoor vertical farm. Seeds were sown in rockwool substrate, with A. brasilense (1.05 × 108 colony-forming units⋅L−1) or R. intraradices (580 propagules⋅L−1) applied weekly via subirrigation. Seedlings received chemical fertilizer, organic fertilizer derived from corn steep liquor and fermented fish by-products, and food waste-derived organic fertilizer at 100 ppm total nitrogen every 2 or 3 days. They were grown indoors at 23 °C under light-emitting diode lighting at a photosynthetic photon flux density of 200 μmol⋅m−2⋅s−1 with an 18-hour photoperiod. Lettuce under organic fertilizers had 75% lower shoot fresh mass and 64% less shoot dry mass compared with lettuce under chemical fertilizer. Similarly, tomato seedlings with organic fertilizers had fewer leaves, 75% less shoot fresh mass, and 67% less shoot dry mass. In both lettuce and tomato, the macronutrient and micronutrient concentrations in plant tissues were generally similar regardless of fertilizer treatments, but nitrogen use efficiency and nitrogen uptake efficiency were lower under organic fertilizers compared with those under chemical fertilizer. The inoculation of A. brasilense or R. intraradices showed limited effects on plant nutrient uptake, nutrient concentrations, and seedling growth in both lettuce and tomato. Further research is necessary to optimize application methods for organic fertilizers and beneficial microorganisms to fully harness the benefits of sustainable alternative fertilizers in soilless and hydroponic crop production.
Effect of Black Soldier Fly Larvae and Food Substrates on Weed Seed Emergence
Authors: Meyers Stephen L. , Arana Jeanine , Giraldo Luz Cardona , Ingwell Laura , Rodríguez Laura , Vargas Nathaly
Published: March 2024

Black soldier fly larvae (Hermetia illucens; BSFL) composting is biotechnology used for organic waste management and an alternative to traditional composting. We designed a two-phase experiment to evaluate the effect of BSFL composting on the emergence of the following six weed species: barnyardgrass (Echinochloa crus-galli), common ragweed (Ambrosia artemisiifolia), giant foxtail (Setaria faberi), ivyleaf morningglory (Ipomoea hederacea), redroot pigweed (Amaranthus retroflexus), and velvetleaf (Abutilon theophrasti). The first experiment phase was in the laboratory (laboratory composting phase), which consisted of 100 seeds of each weed species subjected to five composting treatments [two controls (nontreated and standard Gainesville diet alone) and three types of substrates (standard Gainesville diet, vegetable waste, food waste) + BSFL]. Live pupa weighed 179 mg with the standard Gainesville diet + BSFL and 205 mg with the food waste diet + BSFL. Dry pupa weighed 68 mg and 70 mg, respectively. The BSFL in the vegetable waste + BSFL treatment did not pupate. During the second experiment phase, the composting treatments were placed in a greenhouse to evaluate weed emergence. Emergence in the nontreated control was 62% for barnyardgrass, 38% for common ragweed, 26% for giant foxtail, 66% for ivyleaf morningglory, 3% for redroot pigweed, and 69% for velvetleaf. Compared with the nontreated control, all treatments with BSFL reduced the emergence of each weed species to ≤1%, except for velvetleaf. This study suggests that BSFL composting may effectively reduce weed seed emergence of many weed species and could be a safe alternative to conventional composting processes to minimize weed pressure in compost. However, efficacy may vary by weed species and may be dependent on seed characteristics, such as an impermeable seedcoat.
Tarefas Matemáticas e a formação para a docência em Matemática no Ensino Médio
Authors: Milhomen Eduarda do Carmo , Bomfim Maria Eduarda Domience , Andrade Daniela Maria de , Pina Neves Regina da Silva
Published: March 2024

No segundo semestre de 2022, na disciplina de Geometria para o Ensino II, no Curso de Licenciatura em Matemática da Universidade de Brasília, cinco licenciandos colaboraram com o objetivo de desenvolver uma Tarefa Matemática (TM) relacionada à deformação de ângulos e áreas em projeções cartográficas. Após o estudo teórico sobre Tarefas Matemáticas, o grupo aprimorou a TM por meio de apresentações e debates coletivos na disciplina. Esse processo também envolveu análise conceitual, simulação do desenvolvimento da TM em sala de aula e planejamento para antecipar os possíveis desafios dos alunos. A TM foi desenvolvida em uma turma de 3º ano do Ensino Médio Técnico Integrado ao Meio Ambiente no Instituto Federal de Brasília, Campus Estrutural. Os resultados revelaram que os alunos do ensino médio enfrentaram dificuldades em associar as observações do experimento aos conceitos de distorção, tangência e projeção. Ao longo do processo de construção, validação, desenvolvimento e avaliação da TM, os licenciandos reconheceram a importância do cuidado no planejamento e preparação de ações de ensino de matemática, especialmente quando se busca uma maior interação dos alunos com os conceitos e sua aplicação na realidade.   
Palavras-chave: Tarefa Matemática; Projeções cartográficas; Distorções; Investigação; Geometria.
LARYNGEAL PLASMACYTOMA IN KAHLERS DISEASE: A CASE REPORT
Authors:   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco., Ben Ameur El Youbi A. , Arioua A. ,   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco., Ridal M. ,   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco., Benmansour N. ,   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco., Oudidi A. ,   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco., Hammas N. ,   Anatomopathology Laboratory, Hassan II University Hospital Center - Fes. Morocco., EL Alami El Amine MN. ,   Department of Otolaryngology and Cervicofacial Surgery, Hassan II University Hospital, Fes. Morocco.
Published: March 2024

Multiple myeloma or Kahlers disease is a malignant hematological disorder due to a monoclonal plasma cell proliferation primarily invading the hematopoietic bone marrow. Extra-medullar involvement occurs in 18% of patients with multiple myeloma. Laryngeal Localization remains rare and has been described in a few cases after a literature review.We report the case of a 44-year-old woman who presented an inspiratory dyspnea caused by a laryngeal tumor. The pathological study and bone marrow examination confirmed the laryngeal localization of multiple myeloma. Treatment consisted of chemotherapy with good clinical outcomes over a 2-year follow-up period.
Professional risk as a sustainable development of labor protection
Authors:   Saratov State Law Academy, Sergeenko Yulia S.
Published: March 2024

The changes concerning labor protection are significant for labor legislation. Questions of the application of legislation that arise in practice appear not only when developing documents and ensuring labor protection in an organization, but also when conducting supervisory measures by the State Labor Inspectorate in relation to educational organizations of higher education. During the inspections, violations of labor legislation related to labor safety may be revealed. Safety is the state of protection of subjects of labor law (preservation of their health), which is provided by the employer. The provisioning process itself is not simple. It depends on many reasons contained in the process of performing work duties. One of which is the application of labor law norms that have entered into force. During the implementation of labor relations, the employer, applying labor legislation, must comprehensively guarantee all rights for his subordinates. The extent to which this will be carried out as much as possible depends on the financial balance of the facility, the employer and the employee who must perform duties related to their safety. Now, more than ever, labor relations are changing and transforming to meet new emerging challenges. This forces the employer to change, improve and transform the labor process in the subordinate object. In order to improve the application of labor legislation in practice, it is necessary to identify difficulties, gaps, imperfections and work with government agencies. As a result, we will achieve the effective application of norms-protection, which guarantees safe work and the effectiveness of labor legislation. The article provides an example of a gap in legislation and a way to eliminate it. This will make it possible to improve labor legislation and provide an opportunity to further improve safety in educational organizations.
Application of real-time water temperature prediction system in winter for long-distance water diversion projects
Authors: Xu Zepeng , Liu Mengkai , Huang Minghai , Wen Letian , Guo Xinlei
Published: March 2024

Water diversion projects in high-latitude areas often reduce the risk of ice jams in winter by reducing the water transfer flow, which might cause the waste of water transfer benefits. This paper establishes a real-time prediction system of water temperature in winter, which can predict the change in water temperature by inputting the air temperature forecast data and the current hydraulic data. Taking the middle route of the south-to-north water diversion project as the background, the model parameters calibration and system application testing at different time periods are carried out. The results show that the prediction errors of water temperature for the 1 and 7 days are relatively small, and the prediction errors of water temperature at four observation stations can be controlled within ±0.3 and ±0.6 °C, with the root mean square error (RMSE) ranging from 0.07 to 0.25 and 0.12 to 0.36, respectively. The 15-day water temperature prediction results are greatly affected by air temperature input conditions. The prediction errors for the first 7 days are relatively small, ranging from −0.59 to 0.36 °C, and the errors for the last 8 days increase as the accuracy of the air temperature forecast decreases, ranging from −2.42 to 0.22 °C.
Health risk analysis of nitrate in groundwater in Shanxi Province, China: A case study of the Datong Basin
Authors: Sun Qifa , Lang Guohui , Liu Tao , Liu Zhijie , Zheng Jilin
Published: March 2024

In order to identify and effectively control the impact of NO3− pollution on human health, on the basis of investigation, sampling, analysis and testing, statistical analysis software (SPSS19), groundwater pollution analysis software, Nemera comprehensive index method, correlation analysis method and human health risk assessment model are applied for analysis and research. The results indicate that the groundwater in the study area is mainly Class II water, with overall good water quality. The main influencing factors for producing Class IV are NO3−, Fe, F− and SO42−. The use of agricultural fertilizers is the main source of NO3− exceeding standards in groundwater in this area. There are significant differences in the health hazards caused by NO3− pollution in groundwater among different populations, and infants and young children are more susceptible to nitrate pollution. The division of pollution areas and high-risk groups plays an important guiding role in preventing health risks. The new achievements will help people improve their awareness of risk prevention, caring for the environment, respecting nature and implementing precise policies, promoting society to step onto the track of scientific and healthy development.
Crossed Aphasia without Hemiparesis in a Dextral: A Case Report
Authors: Damodaran Anandi , Abdoqasem Rehab , Bandey Hamid Saima , Nayak kotekar Devdutt
Published: March 2024

Introduction:

Aphasia, also known as language impairment, is a condition that affects the ability to express and understand language, as well as the ability to
communicate. Crossed Aphasia in Dextral (CAD) is defined as aphasia after a right hemispheric stroke. Usually, aphasia is caused by a left-sided
stroke in right-handed individuals. The prevalence of crossed aphasia in right-handed individuals is 0.38% to 3%. CAD is diagnosed when the
following factors are present: aphasia, right-handed patient, no family h/o left-handedness, the structural integrity of the left hemisphere, and
absence of brain damage in childhood. Another entity, Global Aphasia Without Hemiparesis (GAWH), is a rare stroke syndrome presenting with
global aphasia without any weakness and occurs in the lesion of the left-sided peri-sylvian region.

Case Report:

A 56-year-old female with a known case of severe mitral stenosis with chronic AF on warfarin and not on regular medications was brought to our
hospital as she had not communicated for the past day. On initial examination, the patient was conscious, globally aphasic, with left facial lag and
no weakness of limbs. Her initial Computed Tomography (CT) brain scan was normal. She was not thrombolysed as she was out of the window.
Brain Magnetic Resonance Imaging (MRI) showed right frontal, temporal, and parietal infarct in middle cerebral artery territory. She was treated
conservatively with full-dose anticoagulation and, upon discharge, was started on oral anticoagulants. At the time of discharge, the patient was able
to understand a few commands and was having echolalia with non-fluent speech. She was reviewed again at 3 months, and she had a full recovery
of her speech.

Discussion:

CAD is a rare stroke syndrome with low prevalence. Even though all subtypes of aphasic syndromes are seen in CAD, Broca's aphasia is the
common subtype, and men are affected commonly. Most patients also present with apraxia and visuospatial neglect. Our patient had all the criteria
for the diagnosis of CAD and also had GAWH and showed rapid recovery. The cause of the disease in this patient was considered to be two
different lesions involving language areas due to an embolism in her heart.

Conclusion:

This case has been presented for its rarity due to the occurrence of both CAD and GAWH in the same patient in a right-sided infarct.
The Right Ventricle in Pulmonary Arterial Hypertension: An Organ at
the “Heart of the Problem”
Authors: Singh Siddharth , Lewis Michael I.
Published: March 2024

:

Pulmonary Arterial Hypertension (PAH) is a progressive disease with no cure. A major
determinant of outcome is the function of the right ventricle (RV). Unfortunately, progressive RV
dysfunction and failure can occur despite PAH-specific therapies. While initial adaptive hypertrophic
changes occur to maintain cardiac output and preserve contractile function and reserve,
maladaptive changes occur in the RV muscle that contribute to RV systolic and diastolic dysfunction
and failure. These include impaired angiogenesis / decreased capillary density with ischemia,
fibrosis, cardiomyocyte apoptosis and impaired autophagy, inflammation, enhanced oxidative
stress, altered metabolism, etc. Of note, there are no therapies currently approved that offset these
changes and treatment of RV dysfunction is largely supportive only. Further patients often do not
qualify for bilateral lung transplantation because of co-morbidities such as renal impairment.
Thus, a dire unmet need exists regarding the management of RV dysfunction and failure in patients
with PAH.
In this State-of-the-Art review, we comprehensively outline the unique features of the RV compared
to the left ventricle (LV) under normal circumstances and highlight the unique challenges
faced by the RV when confronted with increased afterload as occurs in PAH. We provide detailed
insights into the basis for the adaptive hypertrophic phase as well as detailed commentary into the
pathophysiology of the maladapted dysfunctional state as well as the pathobiological aberrations
occurring in the RV muscle that underlines the progressive dysfunction and failure that commonly
ensues. We also review comprehensively the evaluation of RV function using all currently employed
imaging, hemodynamic and other modalities and provide a balanced outline of strengths
and limitations of such approaches with the treating clinician in mind. We outline the current approaches,
albeit limited to chronic multi-modal management of RV dysfunction and failure. We
further outline new possible approaches to treatment that include novel pharmacologic approaches,
possible use of cellular/stem cell therapies and mechanical approaches. This review is directed
to the treating clinician to provide comprehensive insights regarding the RV in patients with PAH.
Impact of Caffeine Intake Strategies on Heart Rate Variability during
Post-Exercise Recovery: A Systematic Review and Meta-Analysis
Authors: Almeida Bianca Araujo , Morales Anderson Pontes , Ribeiro José Ricardo Claudino , Sampaio-Jorge Felipe , Ribeiro Yasmin Garcia , Barth Thiago , Ribeiro Beatriz Gonçalves
Published: March 2024

Objectives:

The objective of this systematic review and meta-analysis is to evaluate
the influence of caffeine (CAF) intake strategies, taking into account their form, timing, and dosage,
on heart rate variability (HRV) indices in the post-exercise recovery period.

Methods::

The meta-analysis adhered to the Preferred Reporting Items for Systematic Review
and Meta-Analysis (PRISMA) guidelines and is registered in the PROSPERO database
(CRD42023425885). A comprehensive literature search was carried out across MEDLINE, Web
of Science, LILACS, and SCOPUS, concluding in May 2023. We concentrated on randomized
clinical trials comparing CAF supplementation effects to placebo on HRV indices post-exercise
in active adults aged 18 and above. The primary endpoint was the assessment of HRV indices,
measured both prior to and following exercise.

Results:

Of the 10 studies included, 7 were used for the meta-analysis, and all contributed to the
systematic review. The research explored a variety of CAF strategies, spanning different forms
(capsule, drink, gum), times (10, 45, 60 min) and doses (2.1 to 6.0 mg/kg). The outcomes revealed
no substantial variations between the placebo and CAF conditions in terms of both the
square root of the average of successive squared differences between adjacent RR intervals
(RMSSD) (standardized mean difference (SMD) -0.03, 95% CI -0.265 to 0.197, p=0.77) and
high frequency (HF) index (SMD -0.061, 95% CI -0.272 to 0.150, p=0.57). Furthermore, metaregression
analysis, employing a fixed-effects model and accounting for the administered CAF
doses, revealed no significant correlation between caffeine doses and HRV indices (p>0.05).

Conclusion:

In conclusion, there is moderate-certainty evidence suggesting that different CAF
intake strategies, encompassing aspects such as form, time, and dose, do not have a significant
impact on HRV indices recovery post-exercise (i.e., vagal modulation).
The Role of SARS-CoV-2 Spike Protein in Long-term Damage of Tissues and Organs, the Underestimated Role of Retrotransposons and Stem Cells, a Working Hypothesis
Authors: Balzanelli Mario G. , Rastmanesh Reza , Distratis Pietro , Lazzaro Rita , Inchingolo Francesco , Del Prete Raffaele , Pham Van H. , Aityan Sergey K. , Cong Toai Tran , Nguyen Kieu C. D. , Isacco Ciro Gargiulo
Published: March 2024

Coronavirus disease-2019 (COVID-19) is a respiratory disease in which Spike
protein from SARS-CoV-2 plays a key role in transferring virus genomic code into target
cells. Spike protein, which is found on the surface of the SARS-CoV-2 virus, latches onto
angiotensin-converting enzyme 2 receptors (ACE2r) on target cells. The RNA genome of
coronaviruses, with an average length of 29 kb, is the longest among all RNA viruses and
comprises six to ten open reading frames (ORFs) responsible for encoding replicase and
structural proteins for the virus. Each component of the viral genome is inserted into a helical
nucleocapsid surrounded by a lipid bilayer. The Spike protein is responsible for damage to
several organs and tissues, even leading to severe impairments and long-term disabilities.
Spike protein could also be the cause of the long-term post-infectious conditions known
as Long COVID-19, characterized by a group of unresponsive idiopathic severe neuro- and
cardiovascular disorders, including strokes, cardiopathies, neuralgias, fibromyalgia, and Guillaume-
Barret's like-disease. In this paper, we suggest a pervasive mechanism whereby the
Spike proteins either from SARS-CoV-2 mRNA or mRNA vaccines, tend to enter the mature
cells, and progenitor, multipotent, and pluripotent stem cells (SCs), altering the genome integrity.
This will eventually lead to the production of newly affected clones and mature cells. The
hypothesis presented in this paper proposes that the mRNA integration into DNA occurs
through several components of the evolutionarily genetic mechanism such as retrotransposons
and retrotransposition, LINE-1 or L1 (long interspersed element-1), and ORF-1 and 2 responsible
for the generation of retrogenes. Once the integration phase is concluded, somatic cells, progenitor
cells, and SCs employ different silencing mechanisms. DNA methylation, followed by
histone modification, begins to generate unlimited lines of affected cells and clones that form
affected tissues characterized by abnormal patterns that become targets of systemic immune
cells, generating uncontrolled inflammatory conditions, as observed in both Long COVID-19
syndrome and the mRNA vaccine.
Which Laboratory and Clinical Feature are different in Pregnant and Non-pregnant Women with COVID-19? A Cross-sectional Study in the West of Iran
Authors: Talebi-Ghane Elaheh , Radnia Nahid , Daneshvar Fariba , Garousian Maryam , Bashirian Saeed , Khazaei Salman , Alimohammadi Neda
Published: March 2024

Background:

This study aimed to determine the differences in laboratory and clinical
characteristics of pregnant and non-pregnant women with COVID-19 in Hamadan, the west of Iran.

Material & Methods:

This cross-sectional study compared 135 pregnant with 135 non-pregnant
women without underlying diseases and matched by age with COVID-19 from March 2020 to June
2021 in Hamadan, a western city in Iran. Their demographic characteristics, clinical symptoms, vital
signs, and laboratory findings were evaluated using a preset checklist and contrasted between the two
groups. The adjusted odds ratios (ORs) for the outcomes of illness were presented. A considerable
amount of analysis was performed on all data using the SPSS version 26 software.

Results:

In general, there was a significant association between most clinical symptoms and status of
pregnancy. Although the Peripheral oxygen saturation with a pulse oximeter (SPO2) mean was significantly
lower among non-pregnant compared to the pregnant women (89.19±4.52 versus
94.91±3.12; p < 0.001), the mean of heart rate was significantly lower among pregnant women compared
to non-pregnant women (90.59±11.80 versus 96.50±15.02; p = 0.001). The percentage of low
hemoglobin (Hb), abnormal Blood Urea Nitrogen, high Creatinine (CR), high Erythrocyte Sedimentation
Rate and high Lactate Dehydrogenase was significantly higher in non-pregnant women compared
to the pregnant women. Women with pregnancy compared to non-pregnant women and women
with low Hb compared to normal Hb had a considerably increased chance of intensive care unit
/death. Each unit increase in SPO2 and pulse rate resulted in a considerable reduction in this risk. In
addition, women with high CR, shortness of breath and per unit rise in temperature had a considerably
higher chance of staying in the hospital for a longer period of time.

Conclusion:

The clinical and para-clinical manifestations of pregnant women with COVID-19 are
different from non-pregnant women. Although there was a significant difference between the two
groups due to mortality, the percentage of admission to the intensive care unit in pregnant women
with COVID-19 is higher than in non-pregnant women. To avoid these adverse outcomes, pregnant
women should take precautions to avoid COVID-19 infection.
Physical, Chemical and Enzymatic Changes in Amla (Emblica officinalis) Fruit during Growth and Maturation
Authors: Sachan Neelam , Kumar Vivek
Published: March 2024

Background:

Amla (Emblica officinalis) is one of the most prominent fruits in terms of nutritional and medicinal properties and is utilized for the preparation of many traditional pro-cessed foods and in Ayurvedic formulations.

Objective:

This study aims to investigate the enzyme activity and physical and chemical quality parameters during the growth and development stages of amla fruit for the determination of proper harvesting time to get optimum nutrient contents of fruit.

Methods:

The amla fruits of the chakaiya variety were harvested at 135 to 270 days after fruit set (DAFS) in 2021 and 2022 to study the various physical, chemical and enzymatic changes during growth and maturation.

Results:

The geometrical and gravimetric attributes of the fruit, viz. diameter, height, weight, volume, surface area, sphericity, aspect ratio, and radius of curvature increased. However, densi-ty decreased with the growth and maturation of the fruit. Furthermore, the rolling resistance, yel-lowness index and firmness of the fruit increased during the entire harvesting period of 135 to 270 DAFS. Total soluble solids and titratable acidity of the fruits increased only up to 195 DAFS and after that, continuously decreased. In contrast, ascorbic acid concentration grew in the entire growth and development period. Tannin, phenolic compounds and naringin content of the fruit steadily dropped until the final stage of harvest. Pectin Methyl Esterase (PME) activity was detected very low, 0.009 unit/ml at 135 DAFS, but as the fruit grew and matured, activity in-creased to 0.307 unit/ml at 270 DAFS. Polygalactouronase (PG) activity was not detected until 210 DAFS and, therefore significantly increased with maturity.

Conclusion:

Considering the optimal value of all studied physical, chemical and enzymatic at-tributes of the fruit during the entire harvesting period of 135 to 270 DAFS, the optimal harvesting time of the fruit was 210 DAFS.
REGISTER BAHASA SEBAGAI BENTUK BUDAYA KOMUNIKASI DALAM KOMUNITAS PEMAIN PUBG
Authors:   Universitas Brawijaya, Putri Fransiska Tarisa , Hapsari Hafiida Rima ,   Universitas Brawijaya, Pramono Muhammad Zulfikar ,   Universitas Brawijaya
Published: March 2024

Language register research can track the evolution of registers over time and changes in games or in their communities of players. Language registers can be found in any community, one of which is the PUBG player community. This research can provide a deeper understanding of how communication in the PUBG game environment creates a certain culture and norms among players. By understanding language registers, researchers can explore sociolinguistic aspects that create identity and togetherness in the gaming community. The aim of the first research was to find the language register contained in three videos with the same title belonging to the Milyhya channel entitled "Sebuah Candaan Jelek". Then, the second objective is to classify the language registers found into several register functions. The method used in this research is a qualitative descriptive method. The object of this research is the PUBG community in the video "Sebuah Candaan Jelek". The technique used by this researcher is the transcription/note taking technique which is used to record the results of the conversation. Based on the presentation of research results and discussion, it is concluded that there are three forms of register used by the PUBG community in the video "Sebuah Candaan Jelek” which includes the lingual form, the limited selingkung form, and the open selingkung form.
Zusters van Sint Vincentius A Paulo, bekend als ‘de vliegeniers’ in de Gentse volkswijk Brugse Poort
Authors: Derdyn Emilienne
Published: March 2024

Een korte beschrijving wordt gegeven van de realisaties van een nu uit Gent verdwenen kloosterorde: de ‘dochters van liefde van Sint-Vin cen tius a Paulo’. Dat was de officiële naam, maar de leden waren beter ge kend onder de volksnamen afgeleid van religieuze kledij: de ‘vliegeniers’, ‘vliegende nonnen’ of ‘grijze zusters’. De religieuzen engageerden zich in het onderwijs en de ziekenzorg, vooral van de armeren. Enkele van hun vestigingen in de Brugsepoortwijk behielden een sociale functie en zijn nog herkenbaar in het straatbeeld. In deze bijdrage wordt speciaal aandacht besteed aan wat aan hen herinnert in de Kiekenstraat bij de Bevrijdingslaan en tussen de Reinaartstraat (Pierkespark) en Haspel straat, achter de Sint-Jan Baptistkerk.
Do Internal Capabilities Affect Competitive Advantage? The Case of a Regional Owned Company
Authors: Maharani Anita , Kartasunjaya Tammy Kathlia
Published: March 2024

AbstractThis research aims to get an overview of the factors affecting organizational competitive advantage and to obtain insights into the most influential factors concerning organizational competitive advantage. This research used the Integrated Talent Management Scale, Utrecht Work Engagement Scale-9, Employee Satisfaction Scale, Employee Performance Scale, and Competitive Advantage Scale. This research followed a quantitative approach. Then the data used in this research was primary data. The researchers gathered data without intervention. This research followed the variance-based structural equation modeling with partial least squares (SEM-PLS) and used SMART PLS as a tool. This research collected 108 types of data by distributing surveys and using the Likert scale. The sampling method in this research was done through non-random sampling and purposive sampling. The questionnaires were distributed to a Jakarta regional owned enterprise. This research found that employee engagement has no impact on employee satisfaction or employee performance in a regional owned company, and employee satisfaction has no impact on competitive advantage in a regional owned company. Keywords:organization, competitiveness, advantage, factors
Group Acceptance and Commitment Therapy for Recovery From Psychosis: Protocol for a Single-Group Waitlist Trial (Preprint)
Authors: Cugnetto Marilyn L , Morris Eric M J , Bonfield Siobain F , Gates Jesse , Morrison Ilona , Newman Ellie R , Nicholls Julia D , Soares Lisa M , Antonucci Megan T , Clemente Jacinta R , Garratt Claire L M , Goldstone Eliot , Pavone David A , Farhall John
Published: March 2024

BACKGROUND

Psychological interventions, along with antipsychotic medications, are recommended for adults diagnosed with a psychotic disorder. While initially designed to mitigate positive symptoms, psychological interventions targeting personal recovery were developed and aligned with the recovery framework that many mental health services have adopted. Acceptance and Commitment Therapy (ACT) for psychosis is one such intervention that shows promise when delivered in an individual format. There is preliminary evidence that ACT for psychosis in a group format improves recovery.

OBJECTIVE

This trial aims to evaluate the effectiveness of the “Recovery ACT” group program on personal recovery among adults living with a psychotic disorder.

METHODS

Our unfunded study is a multiagency, prospective, nonrandomized, waitlist control, single-group trial of the Recovery ACT group program. The program involves 7 weekly group sessions of 90 minutes duration and a 90-minute booster session held 1 month later. We intend to recruit 160 adults living with a psychotic disorder who enroll in a group that is offered as a routine clinical service at participating public mental health services in Melbourne, Victoria, Australia. The 4 assessment time points are 4-6 weeks before the start of the group program, at the start of the group program, at the end of the group program, and at the booster session. There is an optional midgroup assessment and follow-up study. The primary outcome is personal recovery. Secondary outcomes include participants’ well-being and psychological flexibility processes. Qualitative data are also collected from participants and facilitators.

RESULTS

Recruitment began in September 2019 and is ongoing until 2024, subsequent to a 24-month disruption due to the COVID-19 pandemic. As of the submission of this paper, 93 participants consented to the evaluation, 65 completed T1 measures, and 40 had a complete data set for the proposed analyses.

CONCLUSIONS

This is the first trial evaluating the effectiveness of the Recovery ACT group program on personal recovery for adults living with a psychotic disorder. Findings will contribute to knowledge about psychosocial interventions for adults living with psychosis. This trial may also serve as an example of a partnership between clinicians and academics that can facilitate the translation of research into practice.

CLINICALTRIAL

Australian New Zealand Clinical Trials Registry ACTRN12620000223932; https://anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12620000223932

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/49849
Implementation Documentation and Process Assessment of the PharmNet Intervention: Observational Report (Preprint)
Authors: Eldridge Lori Ann , Meyerson Beth E , Agley Jon
Published: March 2024

BACKGROUND

The number of overdose deaths in the United States involving opioids continues to exceed 100,000 per year. This has precipitated ongoing declarations of a public health emergency. Harm reduction approaches, such as promoting awareness of, ensuring access to, and fostering willingness to use naloxone to reverse opioid overdose, are a key component of a larger national strategy to address the crisis. In addition, overdose reversal with naloxone directly and immediately saves lives. Because of pharmacies’ ubiquity and pharmacists’ extensive clinical training, community pharmacies are well-positioned, in principle, to facilitate naloxone access and education.

OBJECTIVE

In 2022, a single-site pilot study of PharmNet, a community pharmacy intervention incorporating naloxone distribution, awareness building, and referral, showed promising outcomes for both naloxone and resource distribution in the community. As a next step, this study was intended to be a pilot randomized controlled trial of PharmNet in 7 pharmacies. However, due to circumstances outside of the study team’s control, data collection was unable to be fully completed as planned. In keeping with open research standards, we transparently report all available data from the study and discuss trial barriers and processes. We do so both to provide insights that may inform similar studies and to avoid the “file-drawer” (publication bias) problem, which can skew the aggregated scholarly literature through nonpublication of registered trial results or selective publication of findings affirming authors’ hypotheses.

METHODS

This paper reports an in-depth implementation study assessment, provides the available observational data, and discusses implementation considerations for similar studies in independent (eg, nonchain) community pharmacies.

RESULTS

Retrospective assessment of study outcomes and fidelity data provided for robust discussion around how resource differences in independent community pharmacies (vs well-resourced chain pharmacies), as well as high demands on staff, can affect intervention implementation, even when leadership is highly supportive.

CONCLUSIONS

Community pharmacies, particularly independent community pharmacies, may require more support than anticipated to be successful when implementing a new intervention into practice, even if it might affect estimates of real-world effectiveness. Further implementation science research is needed specific to independent community pharmacies. All study elements are outlined in the International Registered Report Identifier (IRRID) PRR1-10.2196/42373. Although this paper reports results associated with that registration, results and conclusions should not be given the weight assigned to findings from a preregistered study.

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/42373
NVIDIA’s “Chat with RTX” Custom Large Language Model and Personalized AI Chatbot Augments the Value of Electronic Dermatology Reference Material (Preprint)
Authors: Kamel Boulos Maged N , Dellavalle Robert
Published: March 2024

UNSTRUCTURED

This paper demonstrates a new, promising method using generative artificial intelligence (AI) to augment the educational value of electronic textbooks and research papers (locally stored on user’s machine) and maximize their potential for self-study, in a way that goes beyond the standard electronic search and indexing that is already available in all of these textbooks and files. The presented method runs fully locally on the user’s machine, is generally affordable, and does not require high technical expertise to set up and customize with the user’s own content.
Multilevel Spinal Canal Stenosis with Ossification of the Ligamentum Flavum in an Achondroplastic Patient : A Case Report
Authors: Widyatama Arya , Moeljono Adam
Published: March 2024

Achondroplasia is the most common form of dwarfism in humans. There are abnormalities of intracartilaginous ossification caused by mutation of FGFR 3 gene resulting in a narrow spinal canal accompanied by neurological impairements in some patients. The neurological impairements could be caused by ossification of ligamentum flavum, disc degeneration, kyphosis of lumbar spine, bony spurs, thickened laminae and facet joints. We reported a case of 23-year-old Indonesian male with achondroplasia, spinal canal stenosis accompanied by ossification of ligamentum flavum presented with progressive myelopathy and neurogenic claudication. Spinal canal stenosis with OLF was observed at L2-L5 level of lumbar spine. Laminectomy with decompression and removal of the OLF was performed at L2-L5. There was an improvement on patient's neurological symptoms and function after the surgery. In this report, we describe a rare case of achondroplasia with OLF presenting with neurological symptoms from multiple level of spinal canal stenosis. We perfromed decompressive wide laminectomy and resection of adherent OLF followed by fusion with instrumentation resulted in the improvement of patient's neurological symptoms and function.
Evaluation of Completeness of Cancer Data Variables on Data Quality in Hospital-Based Cancer Registration Activities at Dharmais Cancer Hospital
Authors: Shalmont Grace , Rahayu Pradnya Sri , Hutajulu Susanna Hilda , Lazuardi Lutfan
Published: March 2024

Background: Cancer is a major burden of disease worldwide, including in Indonesia. As an effort to control the burden of cancer, WHO established National Cancer Control Programs (NCCP) where cancer registration is one of the key points. Dharmais Cancer Center Hospital, appointed as the national cancer center, has the responsibility to conduct a cancer registry in Indonesia. The good quality data of cancer registry according to international standards is beneficial to describe the cancer burden in the country. In Dharmais Cancer Center Hospital, microscopic verification is one of the variables that has not been qualified. Therefore, it is important to evaluate the completeness of cancer data variables toward data cancer quality on hospital-based cancer registry of Dharmais Cancer Center Hospital. To assess the quality of cancer data based on microscopic verification, to evaluate the completeness of hospital-based cancer registry variables and the quality of data based on microscopic verification between complete and incomplete variable groups. Materials and Methods: This quantitative research is an observational study (non-experimental) with cross-sectional study design. It utilizes secondary data from hospital-based cancer registry of Dharmais Cancer Center Hospital for incidence year 2013-2017.Results: Data quality of microscopic verification that assessed on a complete data group is 87,8% and for overall cancer cases is 62%. Among social variables, identity numbers are the most incomplete variable, which is 39%. While among tumor data variables, stage is also the most incomplete variable with 82% data. There are differences between the quality of data based on microscopic verification with the completeness of data, especially among social data variables and tumor data variables. Conclusion: The quality data based on microscopic verification that is assessed on a complete variable group is better than microscopic verification on overall cancer cases. The incomplete variables among social variables are identity number, date of birth, address, and district/province. Whereas on tumor variables, the incomplete variables are stage, treatment, metastasis, and laterality. The completeness of cancer data has an importantrole on data quality based on microscopic verification mainly on social and tumor variables. Improvement and strengthening particularly on management and technical aspects of cancer registration are indispensable
The effect of early childhood mind theory on self-resilience and self-regulated learning ability
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Jae-myoung , Pu Sung-sook
Published: March 2024

Objectives The purpose of this study was to examine the correlation between early childhood mind theory and self-resilience and self-regulated learning ability, and to investigate the effect of early childhood mind theory on self-resilience and self-regulated learning ability.
Methods The subjects of the study were 307 children aged 3 to 5 who were enrolled in kindergartens in Gyeonggi-do, collected data through questionnaires, and conducted descriptive statistics, correlation analysis, and regression analysis to analyze the collected data.
Results First, there was a significant positive correlation between early childhood mind theory, self-resilience, and self-regulated learning ability, indicating that the higher the early childhood mind theory, the higher the self-resilience and self-regulated learning ability. Second, early childhood mind theory was found to have a significant effect on self-resilience, and among the sub-factors of mind theory, wind and emotion had a positive effect and belief had a negative effect. In addition, early childhood mind theory has been shown to have a significant effect on self-regulated learning ability, and among the sub-factors of mind theory, belief has a positive effect on self-regulated learning ability and perception has a negative effect on pro-social regulation.
Conclusions This study confirmed the importance of developing mind theory to enhance early childhood self-resilience and self-regulated learning ability, and suggested that teachers and parents need to make efforts to help early childhood develop mind theory.
A Case study on college students' awareness and demand for community collaborative learning
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Jung-Hui , Lee Kyuwon
Published: March 2024

Objectives The purpose of this study is to provide assistance to educators who wish to develop community collaborative classes by investigating and providing college students' perceptions and demands regarding this type of class.
Methods A demand survey was conducted on 1,486 students at D University in the metropolitan area, participation in community cooperative learning, the expected effects of community cooperative learning, the demand for community cooperative learning, and the operation of community cooperative learning classes.
Results The results showed high interest among college students in community cooperative learning. College students hope that community cooperation programs will be established in all types of classes, regardless of major or liberal arts, and appear to prefer community cooperation classes compared to general lecture classes.
Conclusions In order to overcome the crisis in universities, classes in the form of community cooperative learning need to be actively developed and utilized. Now is the time when all universities must actively develop new classes linked to the local community and make efforts to apply new learning methods.