bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of Safety Leadership in Nursing Management: A Systematic Mixed Studies Review
Authors: Lusianah Lusianah , Sitorus Ratna , Lestari Fatma , Muhaimin Toha , Juliastuti Dyah
Published: April 2022

Background: Safety leadership positively influence safety compliance amongst employees in health care. It is necessary to understand how far nursing management has played its roles in attaining safety leadership.
Objective: This study is aimed to explore the safety leadership implemented by nursing management in enhancing the health care system.
Methods: This study conducted a systematic mixed studies review of current literature focusing on nursing managerial and safety leadership. Five key terms, safety leadership and head nurse or headward, first-line nurse manager, nurse leader, or nurse administrator, were used to retrieve relevant articles. Potential articles were found in seven extensive databases (EBSCO, Sage Publication, Scopus, JSTOR, Wiley online, ProQuest and Emerald). We included English research articles or review papers, available full-text, and published from September 2010 to September 2020. Irrelevant and redundant articles were excluded. Two data extractors analyzed the relevant reports.
Results: The search yielded 40 articles. But, after duplicates were removed, eleven full-text articles involving 5361 respondents were reviewed. The review papers included qualitative studies (n = 3), cross-sectional survey (n = 6), and (quasi) experiments (n = 2). The most significant proportion (40%) of the study was conducted in the American region. Four themes were generated, including role of safety leadership, development of safety leadership, support, and barriers. The review highlights that the nurse leaders play essential role in the development and implementation of safety leaderships in the hospital wards though they face challenges which need supporting team works, professionals, and standards.
Conclusion: Adopting safety leadership as a part of nursing management requires support from policymakers, institutions, and nursing leaders. The leaders should understand the complexities of the institutional structures and functional relationships in the health care system to meet patient safety standards
Analysis of Factors Affecting the Readiness of Health Personnel for COVID-19 Patients Treatment in Hospital
Authors: Indrawati Lina , Karo Marni Br. , Meliyana Ernauli , Alrasyid Harun
Published: April 2022

BACKGROUND: Many health workers have experienced fatigue due to high workloads with the number of patients who were confirmed positive for COVID-19 with moderate and severe symptoms who were hospitalized. Researchers identified several factors that affect the readiness of health workers in the management of COVID- 19 patients, including knowledge, family status, availability of personal protective equipment (PPE), health status, and reward. Optimal self-preparation is needed to achieve COVID-19 management that is in line with expectations by examining these factors more deeply.

AIM: The aim of this study was to identify and knowing factors are affect the readiness of Health personnel for COVID-19 patients’ treatment in hospital.

METHODS: This research method uses a descriptive correlation design with a cross-sectional approach aimed at knowing the relationship between variables, where the independent variable and dependent variable are identified at the same time. The number of samples used as many as 34 students of the transfer class who already work as nurses in hospitals.

RESULTS: There were two factors that had an influence on the readiness of transfer students in the management of COVID-19 at the hospital, namely, the family status factor and the availability of PPE with p values of 0.036 and 0.007 and three factors that had no effect, namely knowledge, health status, and giving rewards with p > 0.05.

CONCLUSION: Family status and the availability of PPE become the main important factors related to readiness of health personnel for patients’ treatment in hospital. Working safely and fully support from the hospital can affect the readiness of the health workers in handling COVID-19 patients.
Does Yoga-Murottal Reduce Dysmenorrhea Pain and Improve Beta-Endorphin Hormone Levels in Adolescents?
Authors: Sumarni Sri , Atifah Shinta Dhian Hasna’ , Ta’adi Ta’adi , Ambarwati Eny Retna
Published: April 2022

BACKGROUND: Dysmenorrhea pain is one of the substantial reproductive problems in teenagers. Combination of Yoga and murottal is used as an alternative to reduce dysmenorrhea pain. Yoga might control dysmenorrhea pain and stimulate the release of endorphins which trigger the body to relax and reduce muscle tension.

AIM: The purpose of this study was to prove that the yoga murottal as an alternative treatment for reducing dysmenorrhea pain and increasing beta-endorphin hormone levels in adolescents.

METHODS: The type of research is true experiment, pre-test–post-test with control group design. Sampling according to the inclusion criteria, respondents were 30 female students. The intervention group was given yoga murottal for 20 min every day during menstruation, followed by 2 times a week, while the control group administered an analgesics medicine. Collecting data used observation sheets and blood samples. Analysis of the data used paired t-test and independent t-test.

RESULTS: There is a significant difference in pain scale in both two groups with p = 0.001. There is a difference in beta-endorphins levels before and after intervention in two groups with p = 0.001. There is no difference of beta-endorphins levels between intervention and control groups with p = 0.201. However, the beta-endorphin level in the intervention group is higher than in the control group (52.9 ng/ml and 47.1 ng/ml, respectively).

CONCLUSION: Yoga murottal increased beta-endorphins levels in and reduced dysmenorrhea pain scale for teenagers.
First record of the Philippine snubnose halfbeak, Melapedalion breve (Actinopterygii: Beloniformes: Hemiramphidae), from Bangka Belitung Islands, Indonesia
Authors: Wibowo Kunto , Wahyudewantoro Gema , Fahmi Fahmi
Published: April 2022

A single specimen (117.1 mm standard length) of Melapedalion breve (Seale, 1910) collected off Lepar Island, Bangka Belitung Islands, Indonesia, represents the first record of M. breve from Indonesian waters and the southernmost record of the species. Melapedalion breve has previously been recorded from the Sulu Sea (southwestern Philippines) and eastern central South China Sea.
Comparative metagenomics of phytoplankton blooms after nutrient enrichment of oligotrophic marine waters
Authors: Pearman John K. , Casas Laura , Michell Craig , Aldanondo Naroa , Mojib Nazia , Holtermann Karie , Georgakakis Ioannis , Curdia Joao , Carvalho Susana , Gusti Amr , Irigoien Xabier
Published: April 2022

Increasing anthropogenic pressures on the coastal marine environments impact these ecosystems via a variety of mechanisms including nutrient loading, leading to eutrophication and increases in algal blooms. Here, we use a metagenomics approach to assess the taxonomic and functional changes of the microbial community throughout a nutrient enriched mesocosm phytoplankton bloom. We tested four different nutrient treatments consisting of either nitrate and phosphate or nitrate, phosphate and silicate, administered on the first day or continuously for the first two weeks of the experiment. Our results show a shift in the taxonomic composition of the community over time that is dependent on the nutrient addition regime. Significant differences in the functional potential of the communities were detected, with an interaction between bloom period (pre-bloom, bloom and post-bloom) and nutrient treatment (p = 0.004). A sharp drop in functional similarity was observed in the first week in all treatments and after 20 days had not returned to pre-bloom levels. Changes within energy metabolism pathways showed a remarkable enrichment of the dissimilatory nitrate reduction pathway in the post-bloom period. Eukaryotic oxidative phosphorylation and photosynthetic antenna proteins were more abundant during the bloom, especially in the continuous treatment with silicate. Our results suggest that continuous (i.e. chronic) nutrient enrichment has a larger effect on the functioning of marine systems compared to a single (i.e acute) addition. A deep understanding of the functional and taxonomic shifts in the community during blooms is essential to reverse or mitigate human impacts on coastal environments.
Le scénario d’une traversée houleuse : le placement familial d’adolescents auteurs de violences sexuelles
Authors: Corré Sonia , Roman Pascal , Estellon Vincent
Published: April 2022

Au sein du service de placement où exerce en tant que psychologue le premier auteur de cet article a été développée une recherche longitudinale qui vise à explorer le fonctionnement psychique des adolescents auteurs de violences sexuelles et les modalités de leur accompagnement éducatif et thérapeutique. L’article propose de se centrer sur leur placement en famille d’accueil, la dynamique relationnelle témoignant des particularités des liens tissés avec les premiers objets. La présentation de la situation de Nicolas mettra en exergue les difficultés, malentendus et usures qui semblent illustrer un scénario qui se répète et qui conduit à la rupture. Les auteurs ouvrent une réflexion, dans une perspective psychodynamique, pour tenter de comprendre les mouvements psychiques à l’œuvre du côté de l’adolescent, notamment sur un plan intersubjectif, dans la perspective développée par René Kaës, et invitent à s’intéresser aux adaptations nécessaires au sein des dispositifs éducativo-thérapeutiques d’accompagnement.
Le syndrome de la couverture tirée comme risque de rupture de liens dans la clinique du placement familial
Authors: Vidal-Bernard Alexandra , Sanahuja Almudena
Published: April 2022

Cette recherche s’intéresse aux problématiques de ruptures de liens dans la clinique du placement familial, notamment celles rattachées au conflit de loyauté pouvant être ressenti par des adolescents placés. Ce syndrome, qui peut être baptisé « syndrome de la couverture tirée », correspond à un phénomène de rivalité entre deux familles, une professionnelle et une biologique avec comme enjeu central l’adolescent. À partir d’une étude de cas paradigmatique menée dans le cadre de suivis thérapeutiques associés à une recherche exploratoire, les auteures, thérapeutes et chercheuses en psychologie clinique, procèdent à une analyse des phénomènes psychiques sous-jacents individuels et familiaux en s’appuyant sur les théories psychanalytiques groupales et familiales. Les résultats montrent que les ruptures de liens sont étroitement associées aux processus complexes d’affiliation et à l’empêchement du processus de séparation-individuation. Mais elles sont également liées à l’échec de la fonction tiers du service de placement.
Sortir de l’invisibilité : inégalités de genre dans les agricultures familiales en Afrique de l’Ouest
Authors: Droy Isabelle , Bidou Jean-Étienne
Published: April 2022

En Afrique de l’Ouest, les agricultures familiales subissent des changements rapides, tant sous l’effet de la globalisation que des transformations sociodémographiques et environnementales. Ces bouleversements affectent la répartition des droits et des ressources au sein des unités familiales, en se traduisant fréquemment par un creusement des inégalités au détriment des femmes. Or, malgré de nombreux engagements politiques en faveur de la réduction des inégalités de genre, les méthodes mobilisées pour l’analyse des agricultures familiales et la mise en œuvre d’actions de développement restent souvent aveugles au genre, contribuant ainsi à la reproduction, voire à l’aggravation des inégalités. Classification JEL : J16, C18, O22, Q12, R 20
Les opérations de relogement des quartiers insalubres à Casablanca : une logique contradictoire entre développement et inégalité
Authors: Samih Kawtar
Published: April 2022

Programme phare de l’action publique marocaine depuis 2004, "Villes sans bidonvilles" vise à à la réduction des inégalités et à la lutte contre l’exclusion. À Casablanca, les quartiers insalubres et les opérations de relogement subissent les effets et les contre-effets de cette mise aux normes. Précaires et situés hors de la ville, les quartiers de relogement apparaissent destinés à redorer l’image internationale de Casablanca plutôt qu'à incarner une cohésion sociospatiale. Basé sur une série d’entretiens de populations, l’article examine cette expérience sociospatiale et en révèle les nouvelles pratiques. Classification JEL : E26, I31, J60, O17, O20
Relationship of Self-Esteem With Body Image and Attitudes Toward Motherhood and Pregnancy
Authors: Zamiri-Miandoab Nasrin , Kamalifard Mahin , Mirghafourvand Mojgan
Published: April 2022

The current study aimed to determine the relationship of self-esteem with attitudes toward motherhood and pregnancy and body image in Iranian pregnant women. This cross-sectional study included 228 women from Tabriz, Iran. A cluster random sampling method was used. Instruments were the Rosenberg Self-Esteem Scale, Scale of Attitudes Toward Motherhood and Pregnancy, and Multidimensional Body-Self Relations Questionnaire. To determine the correlation of self-esteem with attitudes toward motherhood and body image, Pearson correlation test was used in bivariate analysis, and the general linear model (GLM) with adjustment of potential confounders was used in multivariate analysis. There was a direct correlation between self-esteem and body image (
r
= 0.63) and attitudes toward motherhood (
r
= 0.45). Results of the GLM showed a significant improvement in attitudes toward motherhood (
p
< 0.001) and body image (
p
< 0.001) as self-esteem increased. Based on these results, mental health counseling is recommended to promote pregnant women's self-esteem. [
Journal of Psychosocial Nursing and Mental Health Services, 60
(10), 29–37.]
Efficacy and Safety of Surgically Managed Late Traumatic LASIK Flap Displacements in a Study of 66 Cases
Authors: Fernández-Barrientos Yolanda , Ortega-Usobiaga Julio , Beltran-Sanz Jaime , Druchkiv Vasyl , Ramos-Navarro José Luis , González-de-Gor-Crooke José Luis
Published: April 2022

PURPOSE:

To evaluate safety and efficacy in the management of flap displacement after laser in situ keratomileusis (LASIK) and subsequent complications.

METHODS:

This was a retrospective study performed using data recorded at the center's database from October 2002 to August 2021. Efficacy and safety were both converted to binary outcomes (loss of one or more lines and no change or gain in lines of visual acuity). The effects of time from surgery to complication and from complication to repair were assessed and the odds ratios and probabilities were calculated. The same procedure was applied to investigate the effect of these temporal variables on complications.

RESULTS:

A total of 66 eyes with late traumatic LASIK flap displacements were studied. Efficacy remained unchanged in 48 patients (64 eyes, 75%), and safety remained unchanged in 53 patients (59 eyes, 90%). Sixty-six patients (64 eyes, 100%) achieved visual acuity values of 20/40 and 45 patients (64 eyes, 70.3%) achieved values of 20/20. The flap displacement was resolved in the first 24 hours (SD ± 0.1 days). Surgery was performed in 58 patients (65 eyes, 90%). Epithelial ingrowth was the most frequent complication. Patients who underwent surgery tended not to lose lines (
P
= .05). The risk of developing epithelial ingrowth increases with time after LASIK surgery until traumatic flap displacement (odds ratio: 1.001;
P
< .001). The prevalence of dislocation during the study period was 0.012%.

CONCLUSIONS:

Visual safety values were favorable after resolution of the flap complication. Immediate surgical management leads to better visual efficacy, and the time between LASIK and trauma increases the risk of epithelial ingrowth after flap displacement.

[
J Refract Surg
. 2022;38(4):270–276.]
A variety of dynamic $ \alpha $-conformable Steffensen-type inequality on a time scale measure space
Authors: El-Deeb Ahmed A. , Moaaz Osama , Baleanu Dumitru , Askar Sameh S.
Published: April 2022

The main objective of this work is to establish several new alpha-conformable of Steffensen-type inequalities on time scales. Our results will be proved by using time scales calculus technique. We get several well-known inequalities due to Steffensen, if we take $ \alpha = 1 $. Some cases we get continuous inequalities when $ \mathbb{T} = \mathbb{R} $ and discrete inequalities when $ \mathbb{T} = \mathbb{Z} $.
Transmission dynamics of varicella before, during and after the COVID-19 pandemic in Japan: a modelling study
Authors: Suzuki Ayako , Nishiura Hiroshi
Published: April 2022

Public health and social measures (PHSMs) targeting the coronavirus disease 2019 (COVID-19) pandemic have potentially affected the epidemiological dynamics of endemic infectious diseases. In this study, we investigated the impact of PHSMs for COVID-19, with a particular focus on varicella dynamics in Japan. We adopted the susceptible-infectious-recovered type of mathematical model to reconstruct the epidemiological dynamics of varicella from Jan. 2010 to Sep. 2021. We analyzed epidemiological and demographic data and estimated the within-year and multi-year component of the force of infection and the biases associated with reporting and ascertainment in three periods: pre-vaccination (Jan. 2010–Dec. 2014), pre-pandemic vaccination (Jan. 2015–Mar. 2020) and during the COVID-19 pandemic (Apr. 2020–Sep. 2021). By using the estimated parameter values, we reconstructed and predicted the varicella dynamics from 2010 to 2027. Although the varicella incidence dropped drastically during the COVID-19 pandemic, the change in susceptible dynamics was minimal; the number of susceptible individuals was almost stable. Our prediction showed that the risk of a major outbreak in the post-pandemic era may be relatively small. However, uncertainties, including age-related susceptibility and travel-related cases, exist and careful monitoring would be required to prepare for future varicella outbreaks.
Mechanism of Antiviral Activities of Nanoviricide's Platform Technology based Biopolymer (NV-CoV-2)
Authors: Chakraborty Ashok , Diwan Anil , Arora Vinod , Thakur Yogesh , Chiniga Vijetha , Tatake Jay , Pandey Rajesh , Holkar Preetam , Holkar Neelam , Pond Bethany
Published: April 2022

NV-CoV-2 is a nanoviricide that is covalently bonded with polyethylene glycol (PEG) and alkyl pendants. This molecular design is used to attack many strains of coronaviruses in a broad-spectrum manner. The ligand works by competitive inhibition and binds to the same site on the S-protein of SARS-CoV that attaches to the cognate cellular receptor, ACE2. This prevents SARS-CoV from binding and infecting the cell. NV-CoV-2 is designed to bind to the free virion particles at multiple points encapsulate the virus and disable its ability to infect the cells. The multi-point binding interaction, like a nano-velcro-tape, may lead to lipid-lipid fusion of the alkyl chains in the nanoviricide micelle with the lipid envelope of the virus. The virus becomes dismantled to a capsid form before the host immune system becomes involved. This putative mechanism is orthogonal to many other anti-coronavirus agents in development. Thus, it maybe possible to produce a stronger antiviral effect when combining NV-CoV-2 therapy with other anti-coronavirus therapies such as Remdesivir (RDV). NV-CoV-2 can encapsulate other antiviral compounds as well. In this study, RDV was encapsulated and protected from serum-mediated degradation in vivo. As a result, RDV was available for a longer period of time to interact with RNA polymerase and inhibit.
Age and gender effects in European Portuguese spontaneous speech
Authors: Albuquerque L. , Valente A. R. S. , Teixeira A. , Oliveira C. , Figueiredo D.
Published: April 2022

Aging is part of the normal evolution of human beings. However, the knowledge about speech in the older ages is still dispersed and incomplete. Considering conflicting findings reported in prior research, this study aims to contribute to increase our knowledge about age effects on the spontaneous speech of Portuguese adults. In order to analyze the effects of age on rhythmic, intonation and voice quality domains, several parameters were extracted from spontaneous speech produced by 112 adults, aged between 35 and 97. Data were obtained through a picture description task. The results showed that the most consistent age-related effects are an increase in speech pauses, mainly in men, and a Harmonics-to-Noise Ratio (HNR) decrease in women. Speaking fundamental frequency (f0) tends to decrease in women and to slightly increase in men with age. These findings for Portuguese are in line with previous research suggesting that suprasegmental characteristics of speech change with age, with some gender differences.
Hybrid Genetic Algorithm and Modified-Particle Swarm Optimization Algorithm (GA-MPSO) for Predicting Scheduling Virtual Machines in Educational Cloud Platforms
Authors: S Supreeth , Kirankumari Patil
Published: April 2022

Cloud computing is expanding gradually as the number of educational applications is rapidly increasing. To get Educational cloud services, internet connectivity is predominantly important and Cloud Environment uses one of the basic technology to manage the Physical servers effectively ie; Virtualization Technology. In Cloud Computing, the data centers host numerous Virtual Machines (VMs) on top of the Servers. Due to the rapid growth of Educational platforms, the workload of the VM is computationally getting increased. In the Cloud Educational platforms, to execute the jobs IT resources are provisioned over the network. Since the data generated from the client-side is dynamic in nature, it is difficult to allocate the computational resources efficiently. So to enhance the energy efficiency and to provide the resources in an optimized way, a VM Scheduling mechanism with Hybrid Genetic Algorithm-Modified Particle Swarm Optimization (GA-MPSO) is proposed in this work to achieve QoS parameters like reduced Energy consumption, SLA violation, and cost reduction over the heterogeneous environments. The Hybrid G-MPSO develops the optimal range and improves the best range of scheduling the Virtual resources to VMs from Physical Machines (PMs). The proposed approach, when compared to other VM scheduling algorithms, it intensifies the energy consumption to 105KWH, SLA violation rate of 0.08%, reduces the migrations count to 2122, and consumes the overall cost of 2567.68$. The different scheduling methods for VMs are evaluated against the results, which show that the Hybrid GA-MPSO method is far better than the existing algorithms.
The Evaluation of User Experience on Learning Management Systems Using UEQ
Authors: Saleh Ashraf Mousa , Abuaddous Hayfa Y. , Alansari Iman Sadek , Enaizan Odai
Published: April 2022

The rapid development and improvement of learning management system (LMS) is driven by the rise of ubiquitous computing. As LMS design shifts from technology-centric to user-centric, developers need to prioritize user experience (UX) to improve their LMS. LMS as part of an e-learning system can benefit from UX research to measure ease of use and user satisfaction. Many academic institutions around the world prefer to use their own customized LMS, such as: B. Moodle is an open source LMS platform built and maintained by most Jordanian universities. Therefore, UX evaluation and measurement is very important for LMS. Several studies have been conducted to analyze and measure LMS products for user feedback. On the other hand, these studies only partially consider LMS products. Instead of observing the quality of LMS, they conducted a study focused on comparing LMS and gaining awareness. The purpose of this study is to collect comments and feedback and evaluate the UX when dealing with LMS. Using Moodle as a case study, this study evaluates the user experience of LMS. Data were collected from 867 participants from various Jordanian institutions using LMS. An online survey was prepared and distributed through various social media groups. This study proposes to use the UX Survey Tool (UEQ) to evaluate and quantify the user experience of LMS. This study aims to get feedback and evaluate and identify the UX while interacting with the LMS. In general, implementing a user experience questionnaire to evaluate and evaluate an LMS provides not only complete user awareness, but also the relative quality level of the LMS. The results provide feedback and support assistance in the implementation of the LMS.
Effects of a New Media Data Interaction System on Teaching Efficiency in Vocational Education
Authors: Wang Junmei , Liu Jin
Published: April 2022

The new media data interaction system has profound influences on the teaching efficiency of vocational education. Therefore, its effects on the teaching efficiency of vocational education were analyzed in this study. The analysis was carried out from the perspective of the satisfaction of students with the application of the new media data interaction system in their vocational education and teaching practices. According to scale statistics and the multi-grade fuzzy satisfaction calculation model, results reveal that students are relatively satisfied with the services provided by the new media data interaction system and its effects on teaching efficiency, thereby indicating that such teaching mode can lead to good teaching efficiency. These students also have relatively positive attitudes toward teaching activities based on the new media data interaction system, and this teaching mode can improve their academic performance in vocational education, hence achieving good teaching efficiency. Students of classes that use the new media data interaction system also report higher learning efficiency compared with those students in classes that do not use this system.
REMLABNET – Solar System, New Virtual Laboratory with Mathematical Model Using Vector Functions for Primary, Secondary and High Schools and Universities
Authors: Beňo Pavel , Matejdes Milan , Schauer František , Šprinková Sandra
Published: April 2022

The main role of this article is to create a mathematical model using virtual laboratories for primary, secondary and high schools, and universities. The aim of the article is such a mathematical model to be applicable at all levels of education, with a substantial idea to teach students to think more scientifically. Analysis showed us two possible methods of creating a given model. Possible implementation is with differential equations or vector functions. After a thorough consideration and analysis of the subject we chose a vector function that interfere with a larger spectrum of students compared to differential equations. The main contribution of the work is already mentioned and that is a virtual laboratory, which in our case describes the Solar system and its movement using vector functions. This laboratory is useful, from a primary school, where students are getting to know the Solar system to secondary and high schools, and colleges, where educators can use this model on physics and mathematics lessons when taking over teaching vectors.
Using Natural Language Processing Techniques to Assess the Attitudes of Nursing Students During the COVID-19 Pandemic
Authors: Küçük Emine Ela , Küçük Dilek
Published: April 2022

COVID-19 pandemic has a significant impact in the world. It has led to different measures taken by governments to prevent its spread, such as school closures, employment of e-learning, and complete lockdowns. Together with the pandemic, these measures also affected many people, economically and psychologically. This chapter assesses the attitudes of undergraduate nursing students in Turkey during the COVID-19 pandemic, using automatic natural language processing (NLP) techniques. NLP is a branch of artificial intelligence, and it facilitates automatic analysis of natural language texts. Machine translation and sentiment analysis are among significant NLP techniques. Data collection is performed using an online questionnaire, filled by 101 students from three different universities in Turkey. Machine translation is used to translate responses of the students to English, and then sentiment analysis is performed on these translations. The sentiment analysis results can be used by related nursing educators and health professionals.
Neural Architecture Search Network for the Diagnosis of COVID From the Radiographic Images
Authors: N. Sasikaladevi , A. Revathi
Published: April 2022

The outbreak of human-to-human transmissible COVID-19 has caused approximately 64,000 deaths around the world and keeps continuously increasing in an exponential order that has provoked global alarm. To control the spread of the disease, screening large numbers of suspected cases for appropriate quarantine and treatment measures is of higher priority. Since clinical laboratory testing with precise accuracy for huge samples in the infected region remains a great challenge that demands complementary diagnostic methods to combat the disease. In this work, the authors have identified a new AI-based deep learning framework named CORONATE based on neural architecture space search network (NASNET) as a competent choice that can extract graphical features from radiography images referred from the public dataset of x-ray images. This observation endorses that CORONATE model can administer a faster clinical diagnosis well ahead of pathogenic tests with higher accuracy and can empower the medical team to ensure a good control on the outbreak by saving critical diagnosis time.
Preparation and Electrochemical Performance of Li4Ti5O12/Co3O4 Composite as an Anode of Lithium-Ion Battery
Authors: Wang Ming , Bao Hong Ling , Du Liang , Qi Peng Tao , Zhang Xue Ming
Published: April 2022

The Li4Ti5O12/Co3O4 composites were prepared by hydrothermal reaction method with different Co3O4 mass content (3%, 7%, 11%, and 15%). The Li4Ti5O12 nanoparticles were set in-situ on the Co3O4 sheet. Co ion was doped into the Li4Ti5O12 lattice. The first cycle specific capacity firstly increased and then decreased with Co3O4 content increasing, which the discharge capacity reached the peaking value that the first capacity was 1111 mAh/g and the specific discharge capacity retained 240 mAh/g after 200 cycles. After 200 cycles of charge and discharge, the retention of the capacity was 96.4% at 0.1 A/g, and the retention of the capacity was 98.4% at 0.5 A/g.
Formability of Aluminum in Incremental Sheet Forming
Authors: Bhandari Krishna Singh , Chen Wen Ning , Li Si Jia , Jung Dong Won
Published: April 2022

Single point incremental forming (SPIF) process is used to deform complex shapes. Through SPIF process metallic sheet is formed. The formability of a AA5052 is evaluated using SPIF method for industry level product. The utility of SPIF is broad in industries because of the simple operating system of manufacturing and designing metal substances throughout computer design combined with the CNC machine. While forming Mantellic sheet there are many benefits. This process is extensively adopted in automobile, aeronautical, and medical industries for engineering complex parts. In this paper, the main objective is to examine the formability of AA5052 aluminum alloy raw material with various wall angles and operating boundaries using the modified computer numerical control (CNC) milling machine. Here, the shape correctness and the surface roughness are focused for computing the forming depth, wall angle, and spring-back for obtaining improved parts with a proper material with finish surface. For verifying the real-time experiments and evaluating the existence of stress, strain, and thickness variations.
Preparation and Electrochemical Performance of Li4Ti5O12/SnO2 Composite as an Anode of Lithium-Ion Batteries
Authors: Wang Ming , Du Liang , Fang Peng Fei , Bao Hong Ling , Huang Jun Tao
Published: April 2022

Li4Ti5O12/SnO2 composite with different SnO2 contents were prepared by hydrothermal method. SnO2 nanosheets were in situ formed on the surface of Li4Ti5O12 nanoparticles. At the same time, Sn ions were doped into the Li4Ti5O12 lattice, which effectively improved the conductivity of Li4Ti5O12. When the content of SnO2 was 8 %, the electrochemical performance of Li4Ti5O12/SnO2 composite was the best. The first discharge specific capacity was 480.54 mAh/g. The capacity remained at 276.8 mAh/g after 200 cycles at 0.1 A/g, and the capacity retention was as high as 87.4% (compared with the 10th cycle).
Microstructures, Simulations and Solidification Behaviors of A356 Semisolid Aluminium Alloy Prepared by Stirring Integrated Transfer-Heat Technology under Different Cooling Mediums
Authors: Qiu Zhi Yan , Zhou Bing , Lu Shuai , Chen Ke Ping , Xu Chun , Wang Zhan Yong
Published: April 2022

Based on the theory of grain refinement, the microstructures and simulations of A356 semi-solid aluminum alloy under different cooling mediums were studied. The experiment and simulation results show that water cooling is better than any other cooling mediums. Combined with the simulation of stirring and heat dissipation in SIT device, the changes of temperature field and solid fraction of the melt were studied to help understand the nucleation, growth and solidification behavior under the SIT process. During the process, the temperature field of the melt becomes relatively uniform from a larger temperature gradient and the continuous cooling speed is increased. The results also indicate that compared with traditional casting, the microstructure cooled by water are composed of refined rosiness and nearly spherical particles. With the increase of cooling degree, the average grain size decreased from 206μm to 186μm. The solid fraction increases from 4.4% to 12.2% under the no-cooling and air-cooling conditions, while it is more uniform, increasing from 5.1% to 8.8% due to the water cooling.
Preparation and Properties of Environmental-Friendly Ceramsite and Concrete
Authors: Zhang Ju Song , Luan Xi , Chen Xiao Ning
Published: April 2022

Ceramsite was prepared from sludge, oil sludge and building residue, and the ratio of ceramsite and sintering process was determined by orthogonal test. The effects of different ratios and sintering process on the compressive strength and bulk density of ceramsite were studied. The strength and thermal conductivity of ceramsite foam concrete were tested by using prepared ceramsite as light aggregate to determine the optimal ratio scheme of ceramsite foam concrete. By designing the early cracking test of concrete, the cracking inhibition effect of ceramsite in foam concrete was explored, which provided a theoretical basis for the application of foam concrete.
Modeling Process of Manufacturing Parts Using Incremental Forming Process
Authors: Kosimov Nodirbek , Bhandari Krishna Singh , Li Si Jia , Chen Wen Ning , Moon Jinsik , Jung Dong Won
Published: April 2022

In this paper the issues of modeling the process of forming sheet materials using method of incremental forming for the manufacture of thin-walled non-axisymmetric parts. The proposed method of forming implemented by deformation of sheet material by providing the required trajectory of movement of the working tool in order to obtain the surface of a product of a given shape. Simulation and analysis of all experiment results are carried out.
The Influence of Diffuse Element in Solid-State on Dissimilar Joint between Semi-Solid Cast 7075 with 6061 Al Alloy by Diffusion Welding
Authors: Meengam Chaiyoot , Dunyakul Yongyuth , Chainarong Suppachai , Maunkhaw Dech
Published: April 2022

The purpose of this research was to study the diffuse element and mechanical property of Semi-solid casting (SSC) 7075 and 6061 Al alloy from diffusion welding (DW). The results found that Zn elements were successfully diffused. Mg2Si and MgZn2 intermetallics were precipitated from plate-like shape to flake shape. The high bonding temperature and bonding time caused diffuse elements distributed throughout the material. The mechanical property showed that the maximium average tensile strength was 76.80 MPa from bonding temperature at 723 K and 120 min bonding time. The hardness in bonded line was around 63 HV to74 HV.
Early diagnosis of cardiomyopathies by cardiac magnetic resonance. Overview of the main criteria
Authors: Sozzi Fabiola B. , Iacuzio Laura , Belmonte Marta , Schiavone Marco , Bursi Francesca , Gherbesi Elisa , Levy Frank , Canetta Ciro , Carugo Stefano
Published: April 2022

Cardiomyopathies (CMPs) are diseases of the heart muscle. They include a variety of myocardial disorders that manifest with various structural and functional phenotypes and are frequently genetic. Myocardial disease caused by known cardiovascular causes (such as hypertension, ischemic heart disease, or valvular disease) should be distinguished from CMPs for classification and management purposes. Identification of various CMP phenotypes relies primarily upon echocardiographic evaluation. In selected cases, cardiac magnetic resonance imaging (CMR) or computed tomography may be useful to identify and localize fatty infiltration, inflammation, scar/fibrosis, focal hypertrophy, and better visualize the left ventricular apex and right ventricle.  CMR imaging has emerged as a comprehensive tool for the diagnosis and follow-up of patients with CMPs. The accuracy and reproducibility in evaluating cardiac structures, the unique ability of non-invasive tissue characterization and the lack of ionizing radiation, make CMR very attractive as a potential “all-in-one technique”. Indeed, it provides valuable data to confirm or establish the diagnosis, screen subclinical cases, identify aetiology, establish the prognosis. Additionally, it provides information for setting a risk stratification (based on evaluation of proved independent prognostic factors as ejection fraction, end-systolic-volume, myocardial fibrosis) and follow-up. Last, it helps to monitor the response to the therapy. In this review, the pivotal role of CMR in the comprehensive evaluation of patients with CMP is discussed, highlighting the key features guiding differential diagnosis and the assessment of prognosis.
Effect of the Glucagon-Like Peptide-1 Receptor Agonists on Autonomic Function in Subjects with Diabetes: A Systematic Review and Meta-Analysis
Authors: Greco Carla , Santi Daniele , Brigante Giulia , Pacchioni Chiara , Simoni Manuela
Published: April 2022

Background: In addition to the metabolic effects in diabetes, glucagon-like peptide 1 receptor (GLP-1R) agonists lead to a small but substantial increase in heart rate (HR). However, the GLP-1R actions on the autonomic nervous system (ANS) in diabetes remain debated. Therefore, this meta-analysis evaluates the effect of GLP-1R agonist on measures of ANS function in diabetes.Methods: According to the Cochrane Collaboration and Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, we conducted a meta-analysis considering clinical trials in which the autonomic function was evaluated in diabetic subjects chronically treated with GLP-1R agonists. The outcomes were the change of ANS function measured by heart rate variability (HRV) and cardiac autonomic reflex tests (CARTs).Results: In the studies enrolled, HR significantly increased after treatment (P<0.001), whereas low frequency/high frequency ratio did not differ (P=0.410); no changes in other measures of HRV were detected. Considering CARTs, only the 30:15 value derived from lying-to-standing test was significantly lower after treatment (P=0.002), but only two studies reported this measurement. No differences in other CARTs outcome were observed.Conclusion: The meta-analysis confirms the HR increase but seems to exclude an alteration of the sympatho-vagal balance due to chronic treatment with GLP-1R agonists in diabetes, considering the available measures of ANS function.
Investigation of the relationship between miR-33a, miR-122, erythrocyte membrane fatty acids profile, and serum lipids with components of metabolic syndrome in type 2 diabetic patients
Authors: Masoudi Fatemeh , Sharifi Mohammad Reza , Pourfarzam Morteza
Published: April 2022

Background and purpose:

MicroRNAs (miRNAs) are small non-coding RNA molecules acting as critical regulators of post-transcriptional gene expression. MiR-33a and miR-122 have a crucial role in cholesterol and lipid metabolism. Therefore, their dysregulation may contribute to metabolic abnormality and their inhibition may be a useful therapeutic strategy. The objective of the present study was to investigate the relationship between miR-33a, miR-122, erythrocyte membrane fatty acids profile, and serum lipids with components of metabolic syndrome in an Iranian population suffering from type 2 diabetes mellitus (T2DM).

Experimental approach:

Expression of miR-33a and miR-122 was measured by real-time polymerase chain reaction and erythrocyte membrane fatty acid profiles were analyzed by gas chromatography-mass spectrometry.

Findings/Results:

T2DM patients with and without metabolic syndrome had significantly higher miR-33a and miR-122 levels compared to controls. MiRNAs were significantly correlated with saturated fatty acid (SFAs), total SFAs/total polyunsaturated fatty acids (PUFAs) ratio, fasting plasma glucose, triacylglycerols, insulin and homeostatic model assessment of insulin resistance. In addition, there was a significant negative correlation between miR-33a and miR-122 levels and PUFAs, total PUFAs/total SFAs ratio and omega 6 fatty acids.

Conclusion and implications:

Considering the roles of miR-33a and miR-122 in cholesterol and lipids metabolism, it may be concluded that the measurement of their expression may be useful as a potential additional biomarker for cardiometabolic derangement in T2DM patients. In addition, these findings may suggest that the inhibition of these miRNAs by anti-miRNA therapies may be explored as a potential therapeutic strategy.
Design and production of a novel chimeric human growth hormone superagonist fused to human Fc domain
Authors: Mirbaha Samira , Rezaei Marzieh , Emamzadeh Rahman , Zarkesh Esfahani Sayyed Hamid
Published: April 2022

Background and purpose:

Growth hormone (GH) has been known as a crucial metabolic hormone expressed at the pituitary and the other number of cells and tissues and responsible for body growth. Because of the short half-life of GH, daily subcutaneous injections were shown to be more effective for GH therapy. This represents a burden for patients. So, there is a strong effort from the industry to create a long-acting form of GH and lots of technologies like GH fusion proteins are used to increase GH half-life.

Experimental approach:

In this study, the Fc domain of human IgG1 with serine-glycine linkers was attached to the C-terminal of a GH superagonist via molecular cloning. The presence of recombinant vector in E. coli host was confirmed by PCR. SDS-PAGE and western blot analysis showed the expression of recombinant proteins in the bacterial lysate. The binding ability to growth hormone receptors is determined by ELISA.

Findings / Results:

Our results showed that the novel SupGH-Fc has a good binding affinity to its receptor in ELISA in comparison to standard GH, although it has a big size.

Conclusion and implications:

Our data in this study clearly demonstrated the expression of the SupGH-Fc in a recombinant protein expression system. It is an introduction to the production of the new recombinant GH, which can bind to its receptor more effectively than commercial growth hormones and also might have a longer half-life.
Unilateral proliferative diabetic retinopathy following central retinal vein occlusion
Authors: Mohan Sashwanthi , Bhende Muna
Published: April 2022

This case report describes a diabetic patient with nonischemic central retinal vein occlusion who developed findings suggestive of proliferative diabetic retinopathy in the same eye, with a normal retina in the right eye 3 years after presentation.
Surgery for invasive corneal neoplasia in xeroderma pigmentosum – Optimizing outcomes
Authors: Rajagopal Rama , Iyer Geetha , Srinivasan Bhaskar , Pandey Sunita , Subramanian Krishnakumar
Published: April 2022

Nodular corneal invasion in xeroderma pigmentosum is rare. The depth of clinical involvement can be deceptive. Anterior segment optical coherence tomography/ultrasound biomicroscopy can aid in surgical planning. We reviewed the clinical features, surgical details and long-term outcomes of three patients who underwent superficial keratectomy, lamellar keratoplasty, and penetrating keratoplasty for invasive corneal neoplasia. The histopathology revealed squamous cell carcinoma in all three eyes. No recurrence was noted over a minimum follow-up of 4 years. Early surgery is recommended in view of the risk of deeper penetration. Besides surgery, options include plaque therapy. Comorbid conditions are best addressed sequentially, and long-term follow-up is mandatory.
No-touch management in tick infestation of periocular skin
Authors: Gopi Vaisna , Kamaladevi Lathika V , Skariah Charles K
Published: April 2022

Ixodidae ticks are vectors of Lyme borreliosis, Rocky Mountain spotted fever, tick-borne encephalitis, and relapsing fever. We present a case of eyelid tick infestation in a 49-year-old patient for 1 week. A slit-lamp examination suggested it to be a tick tethered on the patient's skin. Complete removal of the tick was done with 2% lignocaine infiltration locally around the swelling. The tick fell off from the periocular skin without any further manipulation. On entomology evaluation, it was categorized to be a hard tick Rhipicephalus sanguineus belonging to the Ixodes family. The patient was put on topical moxifloxacin and chloramphenicol eye ointment. The patient was followed up after 5 days and after 2 weeks and was found to be normal.
Paradoxical reaction presenting with orbital signs in possible intraocular tuberculosis
Authors: Ganesan Suganeswari , Pradhan Arkaprava , Palaniappan Nataraj , Latiff Neethu , Bhende Muna , Ganesh Sudha K
Published: April 2022

We report an unusual presentation of paradoxical reaction (PR) with orbital signs in a case of possible intraocular tuberculosis (POTB). A 15-year-old boy presented with vitreous hemorrhage in the right eye (OD) and multifocal choroiditis in the left eye (OS) and progressed to develop bilateral proptosis, lid edema, chemosis, subretinal lesions, and progression of choroidal lesions following the rapid tapering of oral steroids with anti-tubercular therapy for POTB. The orbital reaction and progressing posterior segment lesions were managed with pulse steroid therapy, oral steroids, intravitreal anti-vascular endothelial growth factor (anti-VEGF), and steroid implant. The orbital involvement is rarely seen in POTB with PR.
Low-flow carotid-cavernous fistula causing oculomotor nerve palsy – More than meets the eye!
Authors: Akkayasamy Kowsalya , Aguiar Marushka , Kumar S Mahesh
Published: April 2022

Isolated oculomotor nerve involvement in a posterior draining CCF is relatively rare. We present the case of a 70-year-old female with complaints of painful left-sided ophthalmoplegia and ptosis. She was detected to have a pupil involving third nerve palsy on the left side. We asked for neuroimaging in the form of MRI and MRA which showed a left-sided low-flow CCF compressing the cavernous and the extra-cavernous portion of the oculomotor nerve. This report stresses the importance of keeping low-flow CCF as a differential diagnosis as early detection can be life-saving.
The eye in lock-down
Authors: Bhate Manjushree , Naik Milind N , Martin Frank J , Varma Ravi
Published: April 2022

We report a rare case of a 3-year-old female child with a severe degree of hypotropia and esotropia of the left eye secondary to presumed myositis from unknown etiology treated with systemic steroids. A magnetic resonance imaging (MRI) of the orbit revealed a bulky left inferior rectus muscle. With a working diagnosis of inferior rectus contracture, and presumed dense amblyopia in the left eye, a free tenotomy of the left inferior rectus muscle along with recession of the left medial rectus restored orthotropia from the locked-down position.