bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerapan Alat Praktek Air Conditioning (AC Trainer) pada SMK Negeri 5 Balikpapan
Authors: Akbar Syaeful , Anhar Wahyu , Basri
Published: December 2021

Sistem air conditioning (AC) mempengaruhi kinerja, kenyamanan, dan kesehatan operator/penumpang kendaraan. Meningkatnya penggunaan perangkat AC pada kendaraan menyebabkan kebutuhan tenaga kerja ahli AC juga meningkat. Tidak adanya peralatan praktek AC pada sekolah kejuruan bidang keteknikan menyebabkan pelaksanaan pembelajaran menjadi tidak maksimal. Melalui kegiatan Pengabdian Kepada Masyarakat (PKM) Politeknik Negeri Balikpapan (Poltekba) tahun 2020 akan dibuat alat praktek AC, yang selanjutnya akan diterapkan kepada mitra pengabdian. Kegiatan pembuatan dan perakitan alat praktek AC terbagi dalam tiga bagian, yakni pembuatan dan perakitan bagian rangka, perakitan komponen AC, serta instalasi listrik. Penerapan alat praktek AC akan meningkatkan fasilitas pembelajaran mitra pengabdian khususnya dalam kegiatan praktek AC.
Penerapan Teknologi Budidaya Tanaman Stroberi Di Desa Pangkalan Kabupaten Indramayu
Authors: Aa Setiawan Aa Setiawan , Kurniawan Yudhy , Wardika
Published: December 2021

The geographical condition of Indramayu, which is in the lowlands, is not the right land for cultivating strawberry plants. But it is not impossible for this plant to grow and develop well. The purpose of this community service program is to provide technical guidance to improve the knowledge and skills of Pangkalan Village young people in cultivating strawberry plants by applying climate engineering technology. The equipment given in this activity is water cooling, air conditioning, temperature and humidity control, and spray machines. This activity can be said to be successful as seen by the skills of the participants in managing tools and growing and developing strawberry plants well.
Menciptakan Teknopreneur Muda Bidang Jasa Service R-HVAC Di Politeknik Negeri Indramayu
Authors: Kurniawan Yudhy , Wardika
Published: December 2021

Salah satu permasalahan besar yang ada di kabupaten Indramayu adalah masih banyaknya jumlah pengangguran yang ditimbulkan terutama dari lulusan sekolah dan perguruan tinggi, sementara tuntutan kebutuhan atau ketersediaan tenaga kerja yang terampil oleh dunia industry belum banyak yang bisa menyerap hasil lulusan tersebut. Berdasar data dari BAPPEDA Kabupaten Indramayu, data Angkatan Kerja tiga tahun sebelumnya sudah mencatat mencapai 782,856 sekitar 63,25% adalah TPAK (Tingkat Pengangguran Angkatan Kerja). Menjawab permasalahan penting di atas, perlu ada upaya konkrit institusi Politeknik Negeri Indramayu (POLINDRA) dalam mewujudkan Tri Darma Perguruan Tinggi yaitu kegiatan pengabdian kepada masyarakat (PKM), dalam hal ini mengadakan program kewirausahaan bagi lulusan Polindra dengan menciptakan unit usaha jasa service bidang Pendingin dan Tata Udara (R-HVAC) untuk membantu mengatasi pengangguran tenaga kerja produktif. Tujuan dari PKM ini untuk menghasilkan teknopreneur muda terdidik berkompeten di bidang pendingin yang mampu bekerja secara mandiri dalam rangka meningkatkan taraf hidup serta menurunkan jumlah pengangguran usia produktif khususnya di wilayah Kabupaten Indramayu. Program ini dilakukan dengan melibatkan alumni mahasiswa khususnya jurusan Teknik Pendingin dan Tata Udara yang memiliki minat berwirausaha dan memiliki kompetensi di bidangnya. Kemudian mereka dididik pengetahuan dan ketrampilannya, wawasan kewirausahaan dan etika kerja, sehingga saat menjalankan usaha dapat dilakukan secara professional dan bertanggung jawab.
Thermodynamic modelling of carbonate-silicate rocks from the Sakar unit, Sakar-Strandzha zone, SE Bulgaria
Authors: Vladinova Tzvetomila , Georgieva Milena
Published: December 2021

The P-T evolution of carbonate-bearing metasedimentary rocks from the Sakar unit (Sakar-Strandzha Zone, SE Bulgaria) has been obtained using Perple_X modelling and conventional geothermometry. The metamorphic conditions vary from greenschist facies (250–350 °C/2–4 kbar) in the Klokotnitsa village area to amphibolite facies (550–650 °C/4.5–6.5 kbar) in the Topolovgrad town area, confirming a general increase of the metamorphic grade at east-west direction.
У рамках і поза ними: як насильство стає «справедливим»
Authors: Вайн Нона
Published: December 2021

Рецензія на збірку есеїв Джудіт Батлер «Фрейми війни. Чиї життя оплакують?» (К: Медуза, 2016) містить короткий огляд книжки, описує контекст її створення, основні проблеми, порушені в дослідженні, його актуальність, а також стислий зміст кожного з есеїв і загальні враження від прочитання.
Management of the Natural Attractions in the Area Simarjarunjung Simalungun North Sumatra Province
Authors: Kusnadi Rinal
Published: December 2021

Nature is the utilization of natural resources and environmental governance has been defined as the object of tourist attraction and to be made the target of tourism potential. The natural potential in Indonesia is very diverse, one of which is the potential of Nature Tourism in North Sumatra. Natural potential that is being developed is only one Nature in The Simarjarunjung. This study aims to determine how the institutional management of the Natural Attractions in the Area Simarjarunjung Simalungun Regency and utilization of natural resources on the activities of the Nature in The Simarjarunjung Simalungun. This research method is qualitative using institutional theory has aspects of that structure, shape and norms. The utilization of natural resources using the theory states there are four aspects, namely, the common property, state property, private property and the common property. The result of this research is the institutional management of the Natural Attractions in The Simarjarunjung have the management of the Combined Forest Farmer Group and the Group Aware of Its Loyal Both as a driver and manager. Natural attractions in The Simarjarunjung managed group and personal with having the structure of the management. Natural resources in the Region's Nature Simarjarunjung have natural resources that is different such is the charm of nature, the mountains, the pine stands, agro-forestry plants and microclimate. The utilization of these natural resources will continue to be managed to improve the local economy.

Keywords: Nature, Simarjarunjung, Institutional Management, Natural Resources.
L’impact de la dette extérieure publique sur la croissance économique au Maroc : essai d’une modélisation économétrique
Authors: TATOUTI Rachid , JABHAOUI Seif elislam , MABROUKI Hassan
Published: December 2021

La relation entre la dette extérieure publique et la croissance économique dans les pays a toujours fait l’objet de controverses et a écoulé beaucoup d’encre. L’objet de cet article est d’analyser empiriquement l’impact de la dette extérieure publique sur la croissance économique au Maroc durant la période 1983 -2019. Pour ce faire, nous avons utilisé une méthodologie déductive, axée en premier lieu, sur la proposition d’une revue de littérature à la fois théorique et empirique traitant cette problématique. Ensuite, on s’est basé sur une étude économétrique, et précisément une modélisation VAR standard en vue de détecter l’impact du financement externe sur la croissance du PIB au Maroc.  A travers l’analyse de fonction de réponse impulsionnelle et de la décomposition de la variance, il s’est avéré que la dette publique n’est pas un déterminant de la croissance économique au Maroc.
The killing effect of Tanshinol on breast cancer cells: insight into the reversion of TGF-𝜷1-mediated suppression of NK cell functions
Authors: Yang Chunmei , Qian Cheng , Zhang Tingting , Zheng Weiwei , Zhang Shan , Wang Shijun , Wang Aiyun , Zhao Yang , Lu Yin
Published: December 2021

Background: Natural killer (NK) cells play an indispensable role in anti-tumor immunity. TGF-β1 is the main accomplice of tumor immune escape, inhibiting tumor immunity mediated by NK cells. It is reported that Salvia miltiorrhiza can promote the immune killing effect of NK cells. In this study, Tanshinol, a water-soluble active component of Salvia miltiorrhiza, was used to investigate its effect on the inhibition of NK cell functions mediated by TGF-β1 in breast cancer. Methods: We constructed a mouse model of breast cancer by tail vein injection, H&E staining and ELISA were used to verify the role of TGF-β1 and the effects of Tanshinol on breast cancer and NK cells. In vitro, we used CCK8 and cytotoxicity assays to preliminarily evaluate the effect of Tanshinol on the anti-tumor effect of NK cells intervention by TGF-β1. We explored the killing activity of NK cells and related signal pathways by immunofluorescence imaging technology, RT-PCR, ELISA and flow cytometry. Also, Western blot, RT-PCR and immunofluorescence experiments were applied to investigate the expression level of the natural killer group 2 member D (NKG2D)-NKG2D ligands (NKG2DL) signal axis, and combined with immunoprecipitation, to detect the formation of NKG2D-DNAX-activating protein of 10 kD (DAP10) complex. Results: TGF-β1 played a role in promoting lung metastasis of breast cancer and inhibiting the secretion of cytotoxic mediators from NK cells, but Tanshinol could reverse it. High-dose Tanshinol also significantly optimized the survival rate of tumor-bearing mice. TGF-β1 could destroy the NKG2D-NKG2DL axis, down-regulate the expression and nuclear accumulation of p-smad2/3. Moreover, TGF-β1 inhibited the activation of PI3K-ERK1/2-PLCγ2 signaling pathway that is related to the degranulation of NK cells, and diminished the expression of degranulation marker CD107a and the release of anti-tumor cytotoxic killing medium of NK cells. However, Tanshinol was able to interfere with the negative regulation of TGF-β1 on the functions of NK cells, mainly through promoting the expression of NKG2D and its molecular chaperone DAP10, thereby propelling the formation of NKG2D-DAP10 complex. Conclusions: Collectively, Tanshinol enables NK cells to activate and release multiple killing mediators to carry out immune attacks on tumor cells.
Novel insights into the role of 5-Methylcytosine RNA methylation in human abdominal aortic aneurysm
Authors: He Yuchen , Zhang Hao , Yin Fanxing , Guo Panpan , Wang Shiyue , Wu Yihao , Xin Shijie , Han Yanshuo , Zhang Jian
Published: December 2021

Background: It remains largely unclear about the function of 5-methylcytosine (m5C) RNA modification in the context of abdominal aortic aneurysm (AAA). In this regard, the present work focused on investigating m5C RNA methylation and related modulator expression levels in AAA. Materials and methods: To this end, we quantified the m5C methylation levels in AAA tissues (n = 32) and normal aortic tissues (n = 12) to examine the mRNA m5C status and m5C modulator expression at mRNA and protein levels. Meanwhile, modulator localization within AAA tissue samples was detected by immunohistochemistry (IHC). Moreover, RNA immunoprecipitation-sequencing (RIP-seq) was also used to analyze the lncRNAs and mRNA binding to Aly/REF, as an m5C reader. Results: m5C expression markedly elevated in AAA in comparison with normal aortic samples in the AAA cases. The major 5-methylcytosine modulators, including NSUN2, NSUN5, and Aly/REF, which represented the major parameters related to the abnormal m5C modification level, were observed up-regulating in AAA tissues at both protein and mRNA levels. In addition, NSUN2 mRNA level remarkably related to Aly/REF expression, and they were co-expressed in the same cells in AAA group. Regarding the cellular location, Aly/REF was associated with inflammatory (CD45+, CD3+) infiltrates. Simultaneously, after screening for reads in AAA tissue compare with anti-Aly/REF group relative to IgG as control, we obtained totally 477 differentially expressed Aly/REF-binding lncRNAs and 369 differentially expressed Aly/REF-binding mRNAs in AAA tissue. The functions of Aly/REF-interacting lncRNA were involved in immune system process and macrophages infiltration. Through regulatory network (lncRNA-mRNA) analysis, our findings predicted the potential mechanism of Aly/REF-induced lncBCL2L1 and Aly/REF-lncFHL1 axis in AAA and inspire the understanding of m5C and lncRNA in AAA. Conclusions: This study is the first to examine m5A modification within human AAA samples. Our results indicate that m5C modulators, namely, Aly/REF and NUSN2, play vital parts in the human AAA pathogenic mechanism, which shed new lights on the function of m5C modification within AAA. Taken together, findings in this work offer a possible RNA methylation modification mechanism within clinical AAA.
A new ultrasound-guided percutaneous electrolysis and exercise treatment in patellar tendinopathy: three case reports
Authors: Fernández Alberto Carlos Muñoz , Carballar Carlos Barragán , Villafañe Jorge Hugo , Pérez Sebastián Martín , Pérez José Luis Alonso , Díaz-Meco Raquel , Jiménez David García , Romero Eleuterio A. Sánchez
Published: December 2021

Purpose: To present preliminary clinical results of the effects of a new treatment with percutaneous electrolysis directed to peripheral tendon and therapeutic resistance exercise, with or without the presence of degenerative zone. Methods: 3 patients with patellar tendinopathy aged 37–45 years with diagnostic of patellar tendinopathy with pain since 5–8 weeks were treated with a novel, less invasive electrolysis technique. Pain severity was measured by Numerical Pain Rating Scale (NPRS). Lower limb functionality was measured by a Victorian Institute of Sport Assessment questionnaire (VISA-P). A clinical interview and ultrasonography assesment were performed before study protocol were carried out. Each participants received 4 to 7 sessions of percutaneous electrolysis (350 μA, 80 s) leaving at least one week between sessions during a total of 8 weeks. During this time, subjects also were undergone a therapeutic exercise protocol of lower limbs resistance training. Results: Pain severity decreased after 3 weeks treatment (p = 0.01) and was practically abolished after 4–7 sessions at 8 weeks (p = 0.2). The lower limb functionality (VISA-P) increased after 3 weeks treatment and the major difference was found at 8 weeks post-intervention (p = 0.001). Thickness of the patellar tendon decreased after 8 weeks treatment (p = 0.01). Conclusions: The present work provides the first evidence that percutaneous electrolysis with a least invasive physiotherapy treatment targeted to peripheral tendon in combination with therapeutic resistance exercise diminished pain, improved funcitonality and showed a tendency to decreased thickness in subjects with patelallar tendinopathy.
Discovery of novel peptide neurotoxins from sea anemone species
Authors: Fu Jinxing , Liao Yanling , Jin Ai-Hua , Gao Bingmiao
Published: December 2021

As primitive metazoa, sea anemones are rich in various bioactive peptide neurotoxins. These peptides have been applied to neuroscience research tools or directly developed as marine drugs. To date, more than 1100 species of sea anemones have been reported, but only 5% of the species have been used to isolate and identify sea anemone peptide neurotoxins. There is an urgent need for more systematic discovery and study of peptide neurotoxins in sea anemones. In this review, we have gathered the currently available methods from crude venom purification and gene cloning to venom multiomics, employing these techniques for discovering novel sea anemone peptide neurotoxins. In addition, the three-dimensional structures and targets of sea anemone peptide neurotoxins are summarized. Therefore, the purpose of this review is to provide a reference for the discovery, development, and utilization of sea anemone peptide neurotoxins.
4th Summer School in Immuno-Oncology, July 1st–3rd, 2021, Athens, Greece
Authors: Kostopoulos Ioannis V. , Orologas-Stavrou Nikolaos , Angelis Nikolaos , Pateras Ioannis S. , Kotsakis Athanasios , Georgoulias Vassilis , Baxevanis Constantin N. , Pawelec Graham , Tsitsilonis Ourania E.
Published: December 2021

The 4th Summer School in Immuno-Oncology was held from July 1st–July 3rd as a web meeting. Many eminent researchers and leading oncologists from Europe and the USA working on basic, translational and clinical cancer research participated, presented, and discussed the most recent advances in cancer immunology and immunotherapy. Besides sharing the newest information in the field of cancer immunology and immunotherapy, the meeting also focused on the actual translation of new knowledge acquired in the lab to the clinical setting; particular emphasis was given to the mode of action of novel therapeutic modalities and to biomarkers helpful for treatment decision-making, as well as to means that may improve cancer immunotherapeutic protocols used for the treatment of a variety of malignancies. The main topics presented by the speakers included: (1) mechanisms of tumor immune evasion and resistance; (2) host-tumor interactions and means to regulate antitumor immunity; (3) exploitation of new biomarkers and tumor or immune signatures able to potentially guide therapeutic interventions; (4) emerging therapeutic modalities for cancer treatment and specific immunotherapeutics for thoracic, genito-urinary, gastrointestinal, skin and breast cancers; and (5) innovative treatment options and alternatives to minimize the toxic adverse events of cancer immunotherapy.
Effects of Awareness of the Beauty Master Compositional System on Job Satisfaction and Turnover Intention of Beauty Workers
Authors: Kim Yoo-Jung , Jin Yong-Mi
Published: December 2021

As the beauty industry grows and the level of beauty technology increases, companies must deploy highly qualified workers, among whom beauty salons are certificates obtained by the best technology hairdressers in the beauty field, but they require high technology, time and cost, but have low acceptance and recognition. Therefore, in this study, we sought to investigate the effect of beauty salon perceptions on compositional systems, job satisfaction and turnover intentions for general hairdressers, and analyzed a total of 289 copies using SPSS21.0 as a self-entry survey. First, female managers in their 40s, who earn more than 5 million won with more than seven years of experience, and secondly, the necessity, adequacy, complement, job satisfaction, and turnover were derived in a single dimension. Third, due to the effect of recognition of beauty functional systems on the composition of beauty functional testing systems, the higher the propensity for recognition, the higher the propensity for appropriateness, and the higher the propensity for subsidiarity. Fourth, job satisfaction showed a fifth definition relationship with a higher propensity for awareness, and a higher tendency for turnover meant a definition relationship with a higher propensity for awareness. As such, it is very important to raise awareness of beauty salons in order to develop the beauty industry and improve advanced technology, and efforts should be made to establish a system to revitalize the beauty salons' system on-site.
Antioxidant and Anti-inflammatory Effects of Fermented Eggplant Fruit Extracts with Leuconostoc mesenteroides KD20
Authors: Lee Bum-Chun , Kim Hee-Sook
Published: December 2021

We isolated Leuconostoc mesenteroides KD20, which has its application as a cosmetic material, while searching for useful microbes in Gangwon-do’s traditional fermented foods. Eggplant fruit extract (EG) was fermented with lactic acid bacteria L. mesenteroides. HPLC analysis results for the component analysis of EG and the fermented eggplant fruit extract (FEG) showed bio-conversion of quercetin 3-O-β-D-glucoside and rutin. To investigate skin protection effects of EG and FEG against skin damage by ultraviolet ray, we measured antioxidation and inhibitory effect of inflammation-related cytokines in keratinocytes irradiated with ultraviolet B (UVB). Biosynthesis of IL- 1α, which is increased with UVB in keratinocytes, was inhibited by 24.7% and 28.3% at 100 μg/ml of EG and FEG, respectively. Biosynthesis of PGE2 in keratinocytes was inhibited by 45.7% and 52.3% at 100 μg/ml of EG and FEG, respectively, indicating a greater effect of FEG. Therefore, EG and FEG can be used as an excellent material for cosmetics with skin protection effect against ultraviolet irradiation in keratinocytes.
Protective Effects of Kyungohkgo on Atopic Dermatitis in HaCaT Cells
Authors: Jo Il-Joo , Choi Mee-Ok
Published: December 2021

Kyungohkgo (KOG) is an oriental herbal medicine that has been used for its various pharmacological effects, which include anti-oxidant, anti-inflammatory and immuno-regulation activities. But its effects and mechanisms of anti-atopic dermatitis (AD) have not been elucidated. HaCaT cells were pre-treated with KOG for 1 h and stimulated with tumor necrosis factor (TNF)-α and interferon (IFN)-γ (10 ng/ml each). After 24 h, cells were harvested to measure the production of reactive oxygen species (ROS) and chemokines such as regulated upon activation, normal T cell expressed and secreted (RANTES/CCL5), Thymus and activation-regulated chemokine (TARC/CCL17) and macrophage-deraived chemokine (MDC/CCL22). To investigate the regulatory mechanisms of KOG, we also assessed the phosphorylation of signal transducer and activator of transcription (STAT1) signaling pathways in HaCaT cells. Treatment of KOG decreased the ROS production and mRNA levels of RANTES, TARC, MDC with a concentration dependent manner. In addition, KOG significantly inhibited TNF-α and IFN-γ induced phosphorylation of STAT1. This could indicate that the KOG shows anti-AD activity mainly through STAT1. Thus, we propose that KOG may be a promising anti-AD skin protector, which could suggest the clinical basis for cosmetics development.
12 Labours Seminar Series (Technology Platform 2): Clinical Workflows
Authors: Gamage Thiranja Prasad Babarenda
Published: December 2021

This seminar will present Technology Platform 2 of the 12 labours project: A Physiome modelling platform for precision medicine. We will describe our efforts to integrate existing workflow and FAIR data management systems to enable researchers to create personalised and automated clinical workflows using the computational physiology models they are developing. Our research into technologies to facilitate clinical translation of these workflows will also be described, including the acceleration of simulations and efforts towards accounting for modelling approximations and uncertainty quantification. We will also describe plans for deploying infrastructure to run these workflows as part of pilot studies within clinical environments.
COMPENSATION FOR INFRINGEMENT OF EXCLUSIVE RIGHTS
Authors: Lando D. , Audzeyeva T.
Published: December 2021

The article defines the fundamental questions of legal nature and functional purpose of compensation for infringement of exclusive rights. The place of compensation is assessed both in the system of civil law remedies in general and in the system of remedies for infringement of exclusive rights in particular. The authors conclude that compensation is a complex (hybrid) form of liability in which the compensatory and punitive functions of civil liability are realized with the prevalence of the punitive one. On the basis of this conclusion, the criterion for determining the amount of compensation is proposed and justified. The legislative consolidation of this criterion and its further development in doctrine and judicial practice will contribute to the correct perception of compensation as a remedy and its application in accordance with its purpose.
THEORY OF PRODUCTIVITY OF PRODUCTION OF COMPLEX PRODUCTS (ON THE EXAMPLE OF DEVELOPMENT OF FROZEN AND DURABLE SOILS)
Authors: Dubrovsky N. , Veretennikova E. , Kameko O.
Published: December 2021

Methods for determining the productivity of a set and a fleet of machines are considered. A method has been developed for calculating the productivity of a set of machines, which makes it possible to determine the possibility of its formation, taking into account the characteristics of the machines and the conditions of their operation under given conditions. A method is proposed for determining the productivity of a fleet of machines, taking into account the influence of a large number of different factors for any period of time. These techniques allow you to determine the effectiveness of the use of various equipment in the implementation of earthworks.
FORMS AND METHODS OF STATE SUPPORT OF VENTURE CAPITAL: WORLD EXPERIENCE AND TRENDS
Authors: Ersh A.
Published: December 2021

In this article the concept of the venture capital is invest-gated and its role in the system of innovative business is examined. The mechanism of venture investment is established. The features of venture financing have been determined. The article also analyzes the experience of state support for venture entrepreneurship on the example of Japan, China, Israel, the United States and the Russian Federation. Recommendations are given on the creation of a system of tax preferences in the Republic of Belarus to stimulate venture capital investments.
STRUCTURAL TRANSFORMATION OF INDUSTR IN REPUBLIC OF BELARUS
Authors: Karpenka E. , Shetakova К.
Published: December 2021

The article examines aspects of the structural transformation of the industrial complex of the Republic of Belarus. The analysis of changes in the structure of the formation of gross output in industry and gross value added in industry in 2011 – 2019 is carried out. The assessment of the tendencies of restructuring in industry is carried out on the basis of the author's model of the structure of the country's industry.
DETERMINATION OF OPTIMAL FUNDING SOURCES FROM A SET OF ALTERNATIVES
Authors: Koshevsky N.
Published: December 2021

The introduction provides a brief review of the literature on methods for assessing the effectiveness of investment projects, based on which the choice of optimal sources of financing is made. In the main part of the work, various scenarios for the implementation of an investment project are disclosed: sources of financing that are alternative to the baseline scenario are attracted. In the final part of the work, the considered scenarios are assessed and conclusions are drawn.For each enterprise, improving the financial and economic efficiency of its activities is one of the priority tasks. These tasks include the need to increase the return on capital, the choice of funding sources that have a positive effect on economic efficiency. This paper examines the ways of choosing the optimal, from the point of view of the impact on economic efficiency, instruments for financing an investment project. A practical case of project financing with an assessment of the effectiveness of the implementation of an investment project is considered. To analyze the alternatives, a financial business model was developed, which allows you to quickly make changes, update performance indicators and make decisions about the required capital structure. It is concluded that the optimal capital structure with the highest NPV indicator and that when assessing the efficiency parameters, it is necessary to make an adjustment for the possible presence in the company's capital structure of funding sources that distort the comparability of the project in relation to projects without such sources (for example, budget grants).
PENGARUH PENYULUHAN KESEHATAN TENTANG PENGGUNAAN ALAT PELINDUNG DIRI TERHADAP PERILAKU PETANI DI DESA PETUKEL BLANG JORONG KECAMATAN BANDAR KABUPATEN BENER MERIAH TAHUN 2019
Authors: Kristina Kristina , Pase Muslimah
Published: December 2021

Pemakaian alat pelindung diri merupakan salah satu cara pencegahan terjadinya keracunan pestisida. Pestisida dapat masuk kedalam tubuh melalui kulit dan sistem pernapasan. Menurut WHO di seluruh dunia terajadi 4 ratus ribu- 2 juta mengalami keracunan pestisida. Tujuan penelitian ini untuk mengetahui pengaruh penyuluhan kesehatan tentang penggunaan alat pelindung diri terhadap perilaku di Desa Petukel Blang Jorong Kecamatan Bandar Kabupaten Bener Meriah Tahun 2019. Penelitian ini menggunakan desain Pra-eksperimen dengan rancangan one group pretes and posttest, populasi dalam penelitian ini adalah seluruh petani yang menggunakan pestisida sebanyak 456 orang. Teknik pengambilan sampel dengan accidental sampling, jumlah sampel sebanyak 30 orang. Instrumen yang digunakan menggunakan kuesioner dan leflet. Analisa data dilakukan denganunivariat dan bivariat menggunakanWilcoxon signed rank test. Hasil penelitian bahwa perilaku sebelum diberikan penyuluhan kesehatan tentang penggunaan alat pelindung diri mayoritas kurang sebanyak 15 responden (50%), perilaku sesudah diberikan penyuluhan kesehatan tentang penggunaan alat pelindung diri mayoritas baik sebanyak 21 responden (70%). Hasil uji statistik dengan uji wilcoxon pengaruh pengaruh penyuluhan kesehatan tentang penggunaan alat pelindung diri terhadap perilaku di Desa Petukel Blang Jorong Kecamatan Bandar Kabupaten Bener Meriah Tahun 2019 dengan nilai P-value 0,000. Kesimpulan penelitian terdapat pengaruh penyuluhan kesehatan tentang penggunaan alat pelindung diri terhadap perilaku di Desa Petukel Blang Jorong Kecamatan Bandar Meriah Tahun 2019. Disarankan untuk pihak aparat desa untuk dapat memberikan informasi tentang penggunaan alat pelindung diri yang baik pada petani sehingga mengurangi terjadinya keracunan pada petani.
HUBUNGAN POLA MAKAN DAN POLA AKTIFITAS FISIK TERHADAP KADAR GULA DARAH PADA PASIEN DIABETES MELLITUS TIPE 2
Authors: T. Eltrikanawati  , Nurlaila  , Tampubolon Masitoh
Published: December 2021

Diabetes Melitus  (DM) adalah penyakit metabolik yang ditandai dengan peningkatan kadar glukosa darah (hiperglikemia) yang terjadi akibat kelainan sekresi insulin, kerja insulin atau keduanya. Jumlah penderita diabetes mellitus di Indonesia sebanyak 425 juta orang, di Batam Jumlah penderita sebanyak 3.008 dengan prevalensi terbanyak di Puskesmas Tiban Baru yaitu 439 penderita (14,6 %). Tujuan Penelitian ini untuk menganalisis hubungan pola makan dan pola aktivitas fisik terhadap kadar gula darah sewaktu pada pasien diabetes mellitus tipe 2. Penelitian ini merupakan penelitian analitik dengan design cross sectional dan teknik pengambilan sampel Pusposive Sampling dengan uji Mann-Whitney. Pengumpulan data menggunakan kuesioner dan lembar observasi kepada 58 responden. Hasil uji menunjukkan p value 0,000 (⍺=0,05) untuk masing-masing variabel. Kesimpulan dari penelitian ini terdapat hubungan bermakna antara Pola makan dan pola aktivitas fisik terhadap kadar gula darah sewaktu pada pasien diabetes mellitus tipe 2.
HUBUNGAN KREDIBILITAS KOMUNIKASI PETUGAS PENYULUH KB MELALUI FASE AIDCDA (ATTENTION, INTEREST, DESIRE, CONVICTION, DECISION ACTION) DENGAN MINAT BER KB PASANGAN USIA SUBUR (PUS) DI DESA MANUNGGAL TAHUN 2019
Authors: Surya Manurung Sarida , Ramadhani Wulan Sari
Published: December 2021

Kredibilitas adalah seperangkat persepsi komunikasi tentang sifat-sifat komunikator. Dalam hal ini terkandung dua hal: pertama kredibilitas merupakan persepsi khalayak, jadi tidak melekat dalam diri komunikator, kedua kredibilitas berkenaan dengan sifat-sifat komunikator.Penelitian ini bertujuan untuk menganalisis hubungan kredibilitas komunikasi petugas penyuluhKB terhadap minat ber KB Pasangan Usia Subur (PUS) di Desa Manunggal, menganalisis kredibilitas komunikasi petugas penyuluh KBdi Desa Manunggal, menganalisis minat ber KB Pasangan Usia Subur (PUS) di Desa Manunggal. Peneliti menggunakan paradigma positivisme sebagai suatu proses komunikasi linier yang mencminkan komunikator  untuk mengubah pengetahuan (sikap atau perilaku) komunikan yang pasif. Hasil penelitian menunjukkan bahwa hubungan kredibilitas komunikasi petugas penyuluh KB terhadap minat ber KB Pasangan Usia Subur (PUS) di Desa Manunggal memiliki hubungan signifikan. Nilaikorelasi Karl Spearman sebesar 0,042 dinyatakan hubungan kedua variabel terdapat hubungan kredibilitas petugas penyuluh KB terhadap minat ber KB Pasangan Usia Subur (PUS) di Desa Manunggal. Kredibilitas komunikasi petugas penyuluh KB Desa Manunggalberdasarkan pada fase AIDCDA(Attention, Interest, Desire, Conviction, Decision, Action)dalam melakukan penyuluhan terhadap minat ber KB Pasangan Usia Subur yang telah dilaksanakan berjalan cukup baik walaupun masih ada kekurangan dalam pelaksanaannya.Dalam hal ini fase yang paling banyak memenuhi kriteria adalah Attention dimana hampir secara keseluruhan responden fokus memperhatikan ke arah komunikator. Sedangkan yang berada di posisi paling sedikit adalah Conviction dimana sebagian responden memilih berbincang kepada rekan sekitar sesama responden mengenai keyakinan untuk memilih jenis KB yang cocok untuk kondisi saat ini. Adapun yang menjadi faktor penghambat yang dialami dalam pelaksanaan sosialisasi yaitu hambatan psikologis, teknis, dan kurangnya komunikator. Minat ber KB Pasangan Usia Subur (PUS) di Desa Manunggalakan dapat ditangani secara baik oleh PLKB dan Pemerintah setempat sesuai dengan perencanaan, pengorganisasian, pelaksanaan, pengawasan dan evaluasi program KB.
HUBUNGAN DUKUNGAN KELUARGA DENGAN MOTIVASI BELAJAR MAHASISWA SELAMA PANDEMI COVID-19
Authors: Saragih Masri , Silitonga Erwin , Sinaga Taruli Rohana , Mislika Mutia
Published: December 2021

Pandemi Covid 19 memberikan dampak yang signifikan dalam keberlangsungan hidup manusia, salah satu dampaknya adalah proses pembelajaran. Proses pembelajaran berubah total dari laring menjadi daring dan ini perlu adaptasi bagi seluruh mahasiswa yang sama sekali belum pernah mengenal metode pembelajaran daring, hal ini akan berdampak pada motivasi mahasiswa selama proses pembelajaran. Oleh karena itu dukungan keluarga sangat penting bagi mahasiswa selama  proses pembelajaran anaknya. Penelitian ini bertujuan untuk menganalisis hubungan dukungan keluarga dengan motivasi belajar mahasiswa selama pandemi covid 19. Desain penelitian yang digunakan adalah analitik korelasi, dengan rancangan cross sectional. Populasi dalam penelitian ini adalah seluruh mahasiswa tingkat 4 Program Studi Ners Universitas Sari Mutiara Indonesia dengan jumlah 85 orang dan teknik pengambilan sampel menggunakan total sampling. Alat Pengumpulan data untuk dukungan keluarga dan motivasi belajar mahasiswa menggunakan kuesioner penelitian dan dianalisis dengan uji statistik Spearman Rank. Hasil penelitian menunjukkan bahwa dukungan keluarga mayoritas sedang (43,5%), sedangkan motivasi belajar mahasiswa selama pandemi covid 19 mayoritas sedang (43,5%) dan terdapat hubungan yang signifikan antara dukungan keluarga dengan motivasi belajar mahasiswa selama pandemi covid-19 dengan nilai p-value 0,000 (p<0,05) dan memiliki hubungan yang sangat kuat dengan koefisien korelasi sebesar 0,787. Sehingga dapat disimpulkan bahwa semakin tinggi dukungan keluarga maka semakin tinggi motivasi belajar mahasiswa selama pandemi Covid-19. Disarankan bagi keluarga untuk melakukan pemantauan dan memotivasi semangat anak dalam mengikuti pembelajaran selama pandemi covid-19.
The New Monument to Victims of Military Sexual Violence in Budapest
Authors: Pető Andrea
Published: December 2021

In January 2020, a resolution in favor of erecting the “Monument to Women Raped in War” was adopted by the General Assembly of Budapest. The project, which included an international design competition, aims for the construction of a memorial by 2022. The resolution was passed with the support of the parties constituting the opposition to the governing Fidesz party, which is exceptional. The article analyzes the history of this bipartisan intervention in Hungarian memory politics.
“The outward shows be least themselves”: Speech Acts, Authority, and Visual Ambiguity in The Merchant of Venice
Authors: Goddard Jeanette E.
Published: December 2021

This article uses Judith Butler’s work on speech-act theory in Excitable Speech to examine The Merchant of Venice. Portia as a woman and Shylock as a Jew are outsiders, and both use the language of the Venetian ruling class to attempt to become legitimate speakers. In other words, they use the language of the powerful to challenge power. Shylock is unsuccessful in achieving the status of legitimate speaker and is punished for his attempt. In contrast, Portia disguises herself as a man and has a legitimate speaker, Bellario, vouch for her performance. This combination leads to her success. Both Shylock and Portia highlight the exclusions of the Christian Venetian men’s normative language, though they do so differently. Shylock highlights that an illegitimate speaker can appropriate the language and the anxiety this creates. Portia’s success demonstrates the failure of those in an authoritative position to accurately identify illegitimate speakers. Additionally, Bellario’s letter demonstrates that not all authorized speakers are invested in maintaining its exclusive hegemony. This suggests that as long as the exclusions that shore up authority are based at least in part on visual recognition, there exists the possibility of exploiting visual ambiguity to produce the effect of authority.
Cannibalizing the Black Atlantic in F. T. Marinetti’s Interwar Writing
Authors: Marzioli Sara
Published: December 2021

In this article, I address Filippo Tommaso Marinetti’s writing that borrows from the cultural discourses of the Atlantic African diaspora of the interwar years. I analyze two texts, the play The Drum of Fire and the short story “The Black Man,” both written in 1922; these are traversed by contemporary anticolonial discourses in Africa and the Black American rhetoric of emancipation, which Marinetti appropriates as prime examples of modernity and revolutionary politics. Far from expressing anticolonial and emancipatory sentiments for people of African descent, I argue that Marinetti coopts these discourses to project Italy at the center of the Atlantic world, as the locale of technological and cultural novelty. Between primitivist stereotypes and celebrations of cultural hybridity, these texts reflect Marinetti’s attention for Black cultures of the Twenties, beyond the well-known “jazz craze.” Steeped in current historical events, including Italian migration to the United States, the texts analyzed here demonstrate the contribution of African diasporic cultural discourses to a pivotal phase of Italy’s own nation building, when the country is striving to establish itself as a modern, politically relevant nation on the international stage.
Daniel Boone and Joshua, the Mohican: American Lives and American Myths
Authors: Wheeler Rachel
Published: December 2021

This article compares the life and legend of Daniel Boone (1734–1820) with that of his obscure contemporary, Joshua (1742–1806), a Mohican man whose life unfolded along a remarkably parallel, yet dramatically different course. Both men were born in the East, and moved steadily westward during their lifetimes, on roughly parallel routes. Both men were adept in Native and White ways. Yet Boone died of old age, while Joshua went to a fiery death as an accused witch at the hands of Tenskwatawa, the Shawnee Prophet. Boone became a legend during his own lifetime, while Joshua has remained consigned to a few footnotes. This article asks what narratives of America are possible with Joshua's story at the fore.
Governing the Living Community of Jesus: Johann Friedrich Köber's Letter on Leadership
Authors: Petterson Christina
Published: December 2021

This article is a transcription and translation of the letter written by Johann Friedrich Köber to the interim leadership council (“Ratskonferenz”) in Herrnhut on January 16, 1762, advising a decision on the future mode of leadership in the Unity. It is an important document because it sets out the reasons for the subsequent change in leadership and locates the authority of the Moravian Church in a governing body rather than in an individual.
Kalsifikasi Tulang dan Proses Regenerasi Ekor Ikan Wader (Rasbora Lateristriata)
Authors: Kerans Geterudis
Published: December 2021

Skeleton merupakan alat gerak pasif yang berfungsi sebagai penopang tubuh dan memberi bentuk tubuh. Morfologi makhluk hidup bagian luar salah satunya dibentuk oleh bentuk skeleton, sehingga dapat dibedakan antara spesies yang satu dengan yang lain. Morfologi atau kenampakan bentuk skeleton berbeda dalam setiap perkembangan, karena mengalami diferensiasi.Pada ikan genus Rasbora, perkembangan skeleton dan perbedaan skeletonnya masih sangat sedikit dikaji, terlebih lagi pada spesies R. lateristriata.Kekhasan lain yang ingin diamati adalah bagaimana ikan ini mampu beregenerasi. Hampir semua organisme hidup mempunyai kemampuan beregenerasi. Kemampuan regenerasi masing-masing organisme tidak sama. Penelitian ini bertujuan untuk mengamati proses kalsifikasi tulang pada Ikan Wader (Rasboralateristriata) dan mengidentifikasi regenerasi ekor ikan wader (Rasbora lateristriata). Hasilnya menunjukan bahwa ikan wader telah mengalami proses osifikasi atau penulangan sehingga pada hasil pengamatan dilihat hampir seluruh tulang ikan wader terwarnai merah yang berarti tersusun atas tulang keras. Sedangkan bagian kecil pada bagian ekor ikan terdapat warna biru yang menunjukan bahwa bagian tersebut tersusun atas tulang rawan.Ekor ikan wader yang telah dipotong utuh siripnya kembali tumbuh mulai hari ke 6 secara perlahan hingga hari ke 21 telah kembali seperti semula.Pada pengamatan ini menunjukan bahwa pada bagian ekor ikan wader terdapat stem sel sehingga ekor ikan dapat mengalami regenerasi.Kata kunci: Ikan Wader (Rasboralateristriata), Kalsifikasi, Regenerasi.
The burden of human immunodeficiency virus, hepatitis B and C virus infections in patients with sickle cell anemia in Uyo, Nigeria: A hospital based cross-sectional study
Authors: Samuel Akpan Idongesit , Etim Onukak Asukwo , Victory Edet Iyanam , Oyedele Oyewumi Ajayi
Published: December 2021

Background: Blood transfusion is an invaluable therapeutic intervention in sickle cell anemia (SCA) patients’ care. Sickle cell anemia patients usually require frequent blood transfusion and are at increased risk of contracting human immunodeficiency virus (HIV), hepatitis B and C virus infections through these transfusions. Aims: To determine the seroprevalence of HIV, hepatitis B and C virus infections in patients’ with sickle cell anemia and the role of blood transfusion in the transmission of the infections. Methods: This was a prospective, observational cross-sectional study conducted on adult patients with SCA attending the Haematology Outpatient Clinic of University of Uyo Teaching Hospital, Uyo, from January 1, 2019 through December 31, 2019. Relevant clinical history was obtained from consenting subjects. Blood samples were collected for hemoglobin electrophoresis and viral antigen/antibody screening using ELISA kits. Data were analyzed using Statistical Package for Social Sciences (SPSS) windows version 23.0. Results: Eight-six patients with SCA participated in the study. Forty (46.5%) of the subjects were male and 63 (73.3%) of the participants were within the age range of 20–29 years. Seventy-five (87.2%) of the subjects had blood transfusion while 11 (12.8%) never received blood transfusion in their entire life. Seroprevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) among the transfused SCA patients in this study was 9.3%, 24.0%, and 18.7% respectively while those not transfused had seroprevalence of 9.1% for HIV and 0% for both HBV and HCV. One (1.2%) of the transfused subjects tested positive for HIV and HCV. There was no statistically significant difference in the seroprevalence of HIV, HBV, and HCV infections in relation to the transfusion status of the subjects (p=0.98, 0.07, and 0.12, respectively). Conclusion: The proportion of our SCA patients who were HIV, HBV, and HCV positive was considerable. Blood transfusion did not significantly influence the seroprevalence rates of these viral infections. Measures aimed at controlling the infections in the patients and the general population should be scaled up.
El Diseño sistémico como herramienta participativa para enmarcar políticas de cuidado perinatal en Colombia
Authors: Niño Cáceres Laura , Gómez López Claudia , Córdoba Loren
Published: December 2021

Este trabajo analiza el cuidado perinatal en áreas rurales en Colombia y utiliza teorías del pensamiento sistémico complejo y el Diseño sistémico, de autores tales como Edgar Morin, Donna Haraway y Peter H. Jones, con el fin de generar una crítica de las prácticas del sistema de salud. Lo anterior se consigue a partir de una serie de mapas sistémicos que permiten definir las relaciones entre los actores principales en el sistema perinatal en Colombia y sus asimetrías. A partir de la metodología utilizada, los autores develan la manera de generar un cuidado perinatal más participativo y equitativo reflejado en políticas concretas.

Adicionalmente la lógica del pensamiento lógico complejo y el Diseño sistémico permite introducir una nueva manera de ver la equidad, la cual se basa en la diversidad, pluralidad de cuidados y actores para incrementar el bienestar de la población que requiere atención perinatal por parte del sistema público de salud. Los argumentos aquí presentados también buscan contribuir a la discusión sobre el rol de la partería ancestral en Colombia, a partir de una mirada crítica del sistema de salud, el cual debe dejar de posponer la institucionalización de la misma para aquellas parteras que así lo quieran.
Implementasi Pemuridan Kristen Dalam Keluarga di Era Disrupsi
Authors: Pramono Yonathan Wingit , Saptorini Sari , Purba Jhon Leonardo Presley
Published: December 2021

Abstrak: Keluarga merupakan dasar dan tempat utama pemuridan Kristen untuk mewujudkan pertumbuhan rohani anak-anak Kristen agar siap menghadapi tantangan kehidupan di era disrupsi seperti saat ini. Menggunakan pendekatan kualitatif deskriptif dengan metode studi literature. Penelitian ini bertujuan untuk menjawab pertanyaan penelitian tentang bagaimana implementasi pemuridan Kristen di dalam keluarga di era disrupsi saat ini. Hasil penelitian menyimpulkan bawah pemuridan Kristen dalam keluarga di era disrupsi merupakan hal yang esensial dan krusial. Orang tua berperan penting melakukan pemuridan Kristen dalam keluarga untuk mendidik dan mengarahkan anak-anak Kristen menjadi generasi yang konsisten dan bertumbuh dalam iman kepada Tuhan dan menjadi murid Kristus yang sejati. Menjadi dewasa dalam kepribadian, kerohanian dan moralitas sehingga tidak mudah terjerumus ke dalam aspek negative dari perkembangan teknologi informasi digital saat ini. Dibutuhkan komitmen dan konsistensi dalam implementasi pemuridan Kristen dalam keluarga di era disrupsi untuk menghindari distraksi atau disrupsi dari berbagai informasi media digital yang ada, sebaliknya harus menyediakan waktu yang khusus untuk melakukan pemuridan dengan memanfaatkan perkembangan digitalisasi teknologi informasi di era disrupsi secara positif. Salah satunya melakukan pemuridan keluarga secara virtual. Dengan demikian pemuridan Kristen dalam keluarga tetap dapat dilakukan walaupun orang tua dan anak terpisah jarak dan tempat.Abstract: The family is the basis and the main place for Christian discipleship to realize the spiritual growth of Christian children so that they are ready to face the challenges of life in this era of disruption. Using a descriptive qualitative approach with a literature study method. This study aims to answer research questions about how to implement Christian discipleship in families in the current era of disruption. The results of this study conclude that Christian discipleship in families in the era of disruption is essential and crucial. Parents play an important role in carrying out Christian discipleship in the family to educate and direct Christian children to become a generation that is consistent and grows the faith in God and becomes the true disciples of Christ. Become mature in personality, spirituality and morality so that it is not easy to fall into the negative aspects of the development of digital information technology today. It takes commitment and consistency in the implementation of Christian discipleship in families in the era of disruption to avoid distraction or disruption from various existing digital media information, on the contrary, must provide special time for discipleship by utilizing the development of digitalization of information technology in the era of disruption in a positive way. One of them is doing virtual family discipleship. Thus, Christian discipleship in the family can still be done even though parents and children are separated by distance and place.