bluuebunny/crossref_metadata_2025 huggingface dataset:
AVAILABILITY AND UTILISATION OF RESOURCES FOR TEACHING AND LEARNING ENGLISH LANGUAGE IN SECONDARY SCHOOLS IN EDO STATE, NIGERIA
Authors: Anthoni IDIAKHOA,
Published: October 2024

The study examined the availability utilisation of learning resources in public and private secondary schools in Nigeria with focus on Central Senatorial District of Edo State. Two research questions were raised. The descriptive research design was adopted in the study. The purposive sampling technique was used to draw a sample of 35 private and 35 public secondary schools from the entire population of all the English language teachers in the 69 public and 70 private Senior Secondary Schools (SSS) in Central Senatorial District of Edo State. A checklist was used to collect data on the availability and utilisation of learning resources in schools. The face and content validity of the instrument Learning Resources Availability and Utilisation Checklist (LERAAUC) .Research questions 1 and 2 were analysed using descriptive statistics (mean (X ̅) and standard deviation (S.D). The results from the analyses showed that the recommended learning resources needed for the teaching of English Language are scantily available and utilised in public and private secondary schools in Edo Central Senatorial District, Nigeria. It was recommended that the state government should ensure that all learning resources such as: print resources and audio/visual resources should be readily provided for the teaching of English Language to promote the teaching and learning of English Language in secondary schools.
Types of Intermittent Fasting and Their Effects on Obesity and Type II Diabetes Mellitus
Authors: Gan Shu Xian , Karissa Patricia , Sou Yong Ling , Low Hui Ching , Low Teck Yew , Simpson Timothy , Tan Paulina Pei Suu , Lee Pey Yee , Zain Shamsul Mohd , Ratnam Wickneswari , Pung Yuh Fen
Published: October 2024

Obesity and type II diabetes mellitus affect millions of people both in Malaysia and worldwide due to sedentary lifestyles and unhealthy diets. Intermittent fasting reduces calorie intake by interweaving eating periods with prolonged fasting periods on a recurring basis. Therefore, it could be a potential solution to induce weight loss, leading to improved blood glucose level as observed in type II diabetes mellitus individuals. However, its feasibility remains unclear. This review aimed to compare the beneficial effects and adverse reactions from different types of intermittent fasting in obese and  type II diabetes mellitus studies. The review was carried out by combing through several online databases. Keywords such as “Intermittent fasting”, “Obesity”, “Type II Diabetes Mellitus” were used and relevant articles were selected. The findings of this review showed that intermittent fasting is feasible and effective in reducing body weight and improving blood glucose. The beneficial effects of intermittent fasting appear to outweigh the adverse reactions. Having said that, intermittent fasting is unsuitable for individuals with packed schedules and certain health conditions such as pregnancy. This review will hopefully shed light on intermittent fasting as a potential intervention to combat obesity and type II diabetes mellitus. Further exploration of intermittent fasting could reduce both the morbidity and mortality rates from non-communicable diseases globally.
Novel Bioactive Peptides from Red Bigeye (Priacanthus macracanthus) Flesh Protein
Authors: Mohamed Nor Salasiah , Amin Amiza Mat , Ahmad Fisal
Published: October 2024

Red bigeye (Priacanthus macracanthus) is a common fish species in Malaysia. This study reported an in silico assessment of the main proteins in red bigeye flesh as precursors for bioactive peptides. Six major proteins were chosen as precursors from the proteomic profiles of red bigeye proteins. Analyses using the BIOPEP-UWM database found that Protein number 4 gave the highest total number of bioactive peptides (5052 peptides), with dominant bioactivity in angiotensin-I-converting enzyme (ACE) inhibition (1571 peptides) and dipeptidyl peptidase-IV (DPP-IV) inhibition (2238 peptides). The ACE inhibitors had a frequency of bioactive fragment occurrences (A) of 0.4098, while the DPP-IV inhibitors gave a frequency of 0.5805. In silico proteolysis using BIOPEP-UWM found that pepsin (pH > 2) was the most promising proteinase in releasing a high number of DPP-IV and ACE inhibitory peptides. A novel peptide with significant potential was identified as QYKF. This study shows that red bigeye is a potential source of antihypertensive and antidiabetic peptides.
Effects of Different Types of Starches on Katjang Goat Meat Emulsion Characteristics
Authors: Zamzurin ‘Ainaa’ Nasuha , Ismail Nur Aqilah , Asyrul-Izhar Abu Bakar , Kumar Pavan , Sazili Awis Qurni , Ismail-Fitry Mohammad Rashedi
Published: October 2024

Katjang goat meat has the potential to be used for emulsified meat product production but the suitable starch type to be applied as the filler is unknown. The present study was undertaken to evaluate the effect of various starches on the quality characteristic of Katjang goat meat emulsion. Katjang goat meat emulsion was prepared by incorporating various starches viz., tapioca starch (TS), sago starch (SS), and wheat starch (WS), as filler by replacing lean meat. The developed emulsion samples were evaluated for physiochemical, proximate, colour, texture, and gel strength. The addition of TS into meat emulsion results in the most stable emulsion as exhibited by the lowest total expressible fluid (%TEF), expressible fat (%EFAT), and cooking loss. There was no significant (p>0.05) difference for the pH, water holding capacity (WHC), texture profile analysis (TPA), and colour values of all the samples. The incorporation of SS in the formulation decreased (p<0.05) the shear force and work of shearing. In conclusion, the incorporation of TS was found optimum to formulate goat meat emulsion with better quality characteristics.
Effect of Different Drying Methods on Retention of Colour, Total Phenolic Content, Flavonoid Content and Antioxidant Activity in Pereskia bleo Leaves
Authors: Zulkipli Nurain Nabilah , Norasmadi Iman Nur Sabrina , Lob Suhaizan , Wan Sembok Wan Zaliha , Suhaimi Nurud Iliani , Mubarak Aidilla
Published: October 2024

Pereskia bleo, a widely cultivated plant known for its medicinal applications, contains abundant phytochemicals, including phenolics and flavonoids, predominantly in its leaves. The drying process, a standard practice for enhancing the shelf life, could affect the bioactive compounds within the leaves. Therefore, this study aims to evaluate the impact of various drying methods on the colour, total phenolic content, flavonoid content, and antioxidant activity of P. bleo leaves. The tested drying methods include shade, oven, microwave, and freeze-drying. The colour of fresh and dried leaves was assessed using a Minolta chromameter. The total phenolic content (TPC) and total flavonoid content (TFC) of the P. bleo leaves extracts were determined using the Folin-Ciocalteu’s and aluminium chloride colourimetric assay, respectively. Antioxidant capacities were analysed with DPPH radical scavenging and ferric-reducing antioxidant power assay (FRAP). The results showed that microwave drying has significantly less impact than the other drying methods on the colour attributes of the leaves (p<0.05). Notably, microwave-dried P. bleo leaves demonstrated significantly higher TPC (77.31 ± 0.70 mg GAE/g dry extract) and TFC (35.79 ± 1.34 mg QE/g dry extract) compared to leaves dried using the other tested methods (p<0.05). Additionally, microwave-dried P. bleo leaves displayed the highest DPPH inhibition (91.62%) and exhibited the most potent IC50 value (76.90 ± 1.06 µg/mL) compared to oven and shade-dried leaves (p<0.05). P. bleo leaves dried with a microwave also recorded a significantly higher FRAP value (62.66 ± 0.10 µg TE/g dry extract) than oven-dried leaves (p<0.05). In conclusion, microwave drying emerged to be an efficient drying method in preserving the colour and antioxidant properties of the P. bleo leaves, suggesting its potential as a favourable drying technique for retaining bioactive compounds in medicinal plant materials.
Mitochondrial Genome of Endangered Hylobatidae, Hylobates agilis and Hylobates lar, of Peninsular Malaysia
Authors: Tingga Roberta Chaya Tawie , Gani Millawati , Md-Zain Badrul Munir
Published: October 2024

Hylobates agilis and Hylobates lar, members of the family Hylobatidae, are classified as endangered species in Malaysia due to threats such as population decline and habitat loss. The aim of this study was to sequence and characterize the mitochondrial genome of H. lar and H. agilis. This study reported the total length of mitogenome of H. agilis and H. lar to be 16,473 and 15,949 base pair (bp), respectively. Each sequence contained 13 protein-coding sequences, 2 rRNAs, 22 tRNAs, and a control region D-loop (H. agilis); meanwhile for H. lar, there are 13 protein-coding sequences, 2 rRNAs, 19 trNAs, and a control region D-loop. Phylogenetic analysis showed both species formed a strong monophyletic clade within Hylobates grouping. Mitogenomic data of this study is essential for future references in evolutionary biology and conservation management of endangered Malaysian gibbons in captivity.
Integrating Scientific Approaches in Digital Learning Materials to Improve Spatial Abilities in Cube Geometry: A Research and Development
Authors: Guci Putri Tipakaden , Siregar Budi Halomoan
Published: October 2024

This research aims to determine the level of validity, practicality and effectiveness of digital teaching materials based on a scientific approach, so that they can improve students' spatial abilities in cube material. This type of research is development research with the ADDIE development model. Research instruments in the research include questionnaire validation sheets, lesson plan validation sheets, digital teaching material validation sheets, test instrument validation sheets, spatial ability tests, as well as teacher and student response questionnaires to digital teaching materials. The research results show that: (1) the scientific approach-based digital teaching materials developed have met the validity criteria based on validator assessments with the average validity of digital teaching materials for material being 3.44 and 3.82 for media in the very appropriate category; (2) the scientific approach-based digital teaching materials developed have met the practicality criteria through: a) the results of the student response questionnaire to digital teaching materials show a practicality percentage of 82.75% in the very practical category, b) the results of the teacher response questionnaire to digital teaching materials show practicality percentage 91.67% in the very practical category; (3) The scientific approach-based digital teaching materials developed meet the effective criteria with: a) classical student learning completeness of 90%, b) more than 65% of students have achieved 75% of the learning objectives for each indicator, c) increasing students' spatial abilities After using digital teaching materials, it can be seen from the students' average score increasing from 47.67 in the pretest to 86.50 in the posttest. The results of the N-Gain analysis which shows that students' spatial abilities have increased by 0.725, meaning they are in the high category.
Comparison of Test Statistics for Testing the Regression Coefficients in the Ridge, Liu and Kibria-Lukman Logistic Regression Models: Simulation and Application
Authors: Perez Melo Sergio , Bursac Zoran , Golam Kibria B.M.
Published: October 2024

Ridge, Liu and Kibria- Lukman regression are methods that have been proposed to solve the multicollinearity problem for both linear and non-linear regression models. This paper studies different Ridge, Liu and Kibria-Lukman regression z-type tests of the individual coefficients for logistic regression model. A simulation study was conducted to evaluate and compare the performance of the test statistics with respect to their empirical sizes and powers under different simulation conditions. Our simulations allowed us to identify among the proposed tests, which ones maintain type I error rates close to the 5% nominal level, while at the at same time showing considerable gain in statistical power over the standard Wald z-test commonly used in logistic regression model. Our paper is the first of its kind in comparing the z-type tests for these different shrinkage approaches to estimation in logistic regression. The results will be of value for applied statisticians and researchers in the area of regression models.
Influencia del sexo, país, IMC, uso de Instagram, moralización de la comida e imagen corporal sobre la dismorfia corporal en adultos jóvenes de España y Venezuela
Authors: Armas Bracho Sabrina , Zambrano Gómez Jessica , Moreno Jiménez Jennifer
Published: October 2024

Body Dysmorphia Disorder (BDD) is characterized by an excessive concern with physical appearance, which has been of interest to the scientific community in recent years. Different variables have been found to influence BDD; therefore, the aim of the present research was to determine the direct and indirect effect of gender, country, age, body mass index, Instagram use, food moralization and body image on dysmorphia; comparing Spanish and Venezuelan nationality. A path analysis was performed with the total sample (208 participants), finding that the variables thatdirectly or indirectly influence are sex, body mass index, food-related guilt, country and body image; also, people who present body dysmorphia behaviors tend to be women, people with high BMI, greater dissonance between their body image and perceived body image, and tend to feel food-related guilt. In addition, in an indirect way, Venezuelans presented greater body dysmorphia behaviors. We conclude the relevance of these variables on BDD and recommend considering these findings when planning intervention strategies and prevention policies.
Peran Guru Pendidikan Agama Katolik dalam Pembentukan Karakter Peserta Didik di Sekolah
Authors: Sudi Mayenti Sormin  , Istoto Rahardjo
Published: October 2024

The development of character education in schools in modern times is a challenge for Catholic Religious Education teachers in forming a generation with noble character. A Catholic Religious Education teacher is bound by the obligation to carry out the role of shepherd within the scope of education. Catholic Religious Education Teachers play the role of mentors in their duties, namely educating, so they have duties as journalists and educators. As a preacher, a Catholic religious education teacher takes on the task of proclaiming the news of salvation. Meanwhile, as educators, the task of Catholic Religious Education teachers is to guide students towards maturity, both physically and spiritually mature.  Students who are spiritually mature will have noble character.  To achieve this noble character requires character education which cannot be separated from the role of a Catholic Religious Education Teacher. It is hoped that character education will be able to form a generation whose existence will provide the widest possible benefits in daily life both at home, at school and in society. A literature review approach is used to write articles in order to develop an in-depth understanding to improve the role of Catholic religious education teachers in shaping the character of students in schools. The results of the research in this article conclude that Catholic Religious Education Teachers have an important role in shaping the character of students at school.
THE ROLE OF SYNCHRONOUS TRANSLATION IN LINGUISTICS
Authors:   Independent researcher, Namangan, Namangan District, School 3, Uzbekistan, qizi Parpibayeva Maftuna Zafarjon
Published: October 2024

This article discusses the role of synchronous translation in linguistics and its study by scholars around the world.
Preventing Miscarriage of Justice Using Artificial Intelligence in Pakistan
Authors: Bhatti Amir Latif , Shah Dr. Sardar Ali , Bhatti Dr. Abdul REHMAN , Jamali Sajjad Ali
Published: October 2024

A miscarriage of justice is considered a situation when an incorrect decision has been made in a trial, and a guilty person is sentenced and punished. This is a very common problem in the criminal justice system of Pakistan, which has not been rectified for a very long time. In spite of measures being taken in the quest to eliminate such occurrences, miscarriages of justice are apparent for various causes, including wrong eyewitness identification, tainted confessions and inadequate counsel. The failure of justice is a denial of rights as well as the offenders to justice compartments the system's credibility. In recent years, with the aid of stiff progress in artificial intelligence (AI), it seems probable that miscarriages of justice can be reduced by accurately and efficiently facilitating criminal justice. Hence, this research adopts a doctrinal method to analyze the factual position of the miscarriage of justice system in Pakistan. This work will be very useful in dealing with the problem of miscarriage of justice in Pakistan. Therefore, it can be claimed that by defining the causal factors of wrongful convictions and providing specific recommendations, this study may help build a more efficient and just criminal justice system in Pakistan.
Fighting Medical Misinformation: What Physician Leaders Need to Know
Authors: Butcher Lola
Published: October 2024

The dangerous rise of misinformation and disinformation about health and healthcare undermines the work of physicians and other healthcare workers. Physicians are well-positioned to counter inaccurate information because their patients put a high degree of trust in them. Strategies at the individual and organizational levels are discussed.
When the Detour Becomes the New Road
Authors: Lo Chin Eliza
Published: October 2024

This article recounts the author’s non-linear career journey in medicine, highlighting the unexpected detours and challenges faced, especially balancing motherhood with professional aspirations. Initially set on a traditional academic path, the author pivoted because of family needs, leading to diverse roles in clinical practice, academic settings, and association leadership. Through perseverance and serendipity, she found fulfillment in unconventional opportunities, particularly within the American Medical Women’s Association (AMWA). The narrative emphasizes the importance of adaptability, mentorship, and the value of detours in shaping a rewarding career. The article concludes with reflections on leadership, teamwork, and the significance of giving grace and gratitude in professional growth.
Analise de variáveis climáticas da borda do córrego 8 de abril em Cuiabá-MT – uma abordagem comparativa de dois períodos
Authors: Guimarães Marcos Lázaro , Novais Jonathan Willian Zangeski
Published: October 2024

A cidade de Cuiabá-MT que por muitos anos foi conhecida como cidade verde, vem passando por transformações, que são características das cidades em processo de expansão urbana. As ocupações urbanas, em sua grande maioria, começam à beira de um curso d’água, que é o primeiro a sofrer com o estado de degradação. A solução mais comum encontrada é a canalização e, até mesmo, o tamponamento dos córregos urbanos. O presente trabalho visa realizar a análise comparativa, em dois períodos, das variáveis climáticas “Temperatura do Solo” e “Umidade Relativa do Ar”. Como resultado da comparação do comportamento das variáveis climáticas, não observou-se diferenças significativas entre os períodos quente chuvoso e quente seco; apenas houve variação diária entre às 8h, 14h e 20h. Tampouco houve diferenças entre os valores das variáveis climáticas quando medidas em superfícies de “Asfalto” e “Concreto”.  Como forma de mitigar os efeitos da degradação ambiental, foi apresentada proposta de intervenção multidisciplinar para córrego 8 de Abril, Cuiabá-MT.
Saúde global e condições crônicas não-transmissíveis: reflexões sobre os comportamentos sociais na contemporaneidade
Authors: Pereira Natan David , Oliveira Natan Nascimento de , Harmuch Camila , Druciak Cristiane de Azevedo , Barreto Mayckel da Silva , Oliveira Rosana Rosseto de , Vissoci João Ricardo Nickenig , Salci Maria Aparecida
Published: October 2024

Introdução: As Condições Crônicas Não Transmissíveis são consideradas um grave problema de saúde global e estima-se que um quinto da população mundial apresenta probabilidade de morte prematura por esta causa. Influenciadas por aspectos políticos, econômicos, sociais e culturais, tais doenças se relacionam ativamente à saúde global, tendo em vista a maneira como os indivíduos e a sociedade se relacionam e conduzem seus hábitos de vida. Diante desse contexto, questiona-se: qual a influência da globalização sobre os fatores determinantes para a ocorrência de tais doenças na população? Desenvolvimento: A acelerada globalização resulta numa série de fatores que podem ser prejudiciais à população, entretanto com menores percepções da influência desta sobre os determinantes sociais de saúde em países desenvolvidos. Diversos profissionais são responsáveis pela compreensão dos determinantes sociais, cuidados de saúde holísticos e atividades que objetivem identificar os fatores de risco para ocorrência de agravos à saúde, além do planejamento de ações e implementação de cuidados para a melhoria de indicadores de saúde. Assim, infere-se a necessidade emergente de alterações complexas e abrangentes em nosso sistema de saúde, considerando a heterogeneidade e aspectos atrelados a toda população dos mais diversos países. Considerações Finais: A saúde global pode exercer influência direta sobre as condições de saúde e a ocorrência de doenças na população de todo o mundo. Ressalta-se a importância de uma reflexão acerca das desigualdades observadas entre países conforme sua renda e a implementação de políticas de saúde inclusivas, na mitigação de comportamentos prejudiciais ao planeta e à população.
Aprendizagem das crianças no contexto da pandemia Covid-19: subsídios para o Programa Saúde na Escola
Authors: Esperança Tais Lima de Deus , Picoli Renata Palopoli , Nascimento Edinalva Neves , Nascimento Débora Dupas Gonçalves do
Published: October 2024

O novo coronavírus causou mudanças abruptas na sociedade mundial e a necessidade de isolamento gerou o maior impacto sobre a educação no último século. Este estudo descritivo-exploratório de caráter qualitativo tem como objetivo analisar os efeitos da pandemia de COVID-19 na aprendizagem das crianças. Para tanto, foram entrevistados 20 profissionais da educação nas escolas municipais de ensino fundamental assistidas pelo Programa Saúde na Escola em Campo Grande, Mato Grosso do Sul, entre outubro de 2021 e junho de 2022. Os dados coletados em entrevistas semiestruturadas agendadas foram analisados e categorizados. Os resultados demonstraram fragilidade do ensino remoto, baixa participação nas atividades on-line, falta de acesso às tecnologias e aumento das vulnerabilidades econômicas e sociais, o que causou prejuízo no desenvolvimento e aprendizagem dos educandos, além de sofrimento psíquico na comunidade escolar. Observou-se conhecimento superficial dos professores acerca do Programa Saúde na Escola e pouca participação na construção das intervenções. Sugere-se uma reestruturação do Programa Saúde na Escola voltada à intersetorialidade na elaboração das ações, em consonância com as demandas da comunidade escolar, para minimizar os danos sofridos pelas crianças e estabelecer sua devida rede de proteção.
As várias facetas da religião: um olhar segundo Berger
Authors: Sfalsin Carlos Antonio , Ribeiro Katy Kenyo
Published: October 2024

A religião é uma das invenções humanas que sempre acompanhou a sociedade em sua trajetória. Atualmente, estamos vivenciando diversos acontecimentos multisetoriais ligados a informática e a internet. Neste sentido, muitos autores ligados a sociologia fazem projeções de que a religião está em decadência, e que ela vai sucumbir aos efeitos das redes sociais e da internet. Neste sentido, muitos afirmam que o número de religiões criadas em cada país está diminuindo, levando a pensar que os diversos meios de relacionamento e intercâmbios estão cada vez mais presentes diminuindo assim a dependência de uma religião ou mesmo de uma igreja para poder se apoiar. Em sentido oposto, Peter Berger vem afirmando que a religião não irá se acabar, e sim ela está se transformando, e ao contrário do que se pensa, a religião se transforma com a sociedade, bem como o aumento das religiões criadas em cada país. Iremos trazer neste trabalho, alguns pensadores neste sentido.
Abordagem odontológica a pacientes com Transtorno do Espectro Autista
Authors: Sousa Thais Costa Martins De , Dias Vanessa Rodrigues , Oliveira Marlene Ribeiro de
Published: October 2024

Todo profissional de odontologia está apto a atender um paciente autista, porém, devido esses pacirntes apresentarem hábitos individuais que podem interferir no bom atendimento, é importante que o Cirurgião-Dentista conheça diversos manejos e abordagens para oferecer um atendimento odontológico completo e satisfatório. O presente estudo tem como objetivo revisar as evidências cientificas disponíveis na literatura sobre o manejo e abordagens utilizados no atendimento ao paciente com Transtorno do Espectro Autista no consultório odontológico. Trata-se de uma revisão integrativa da literatura realizada por meio de artigos científicos publicados nas plataformas digitais Google Acadêmico, Scientific Electronic Library Online e PudMed. Foram encontrados 33.563 artigos. Porém, apenas 7 artigos se mostraram relevantes de acordo com o objetivo da pesquisa. Devido o paciente portador desse transtorno apresentar dificuldades a mudanças de rotina, é necessário adequar sua rotina a consultas periódicas com o cirurgiao dentista desde a sua infância, para que ele se acostume com o ambiente odontológico e assim possa ser atendido rotineiramente prevenindo as inúmeras patologias bucais. Também é efetivo preconizar um atendimento calmo e com sons baixos, sempre controlando a entonação vocal, utilizando distrações e, na orientação sobre a higiene oral, deve-se realizar repetições sequenciais de movimentos. Os pacientes com autismo possuem padrões únicos e individuais de comportamento social e de comunicação, por isso, é indispensável que o Cirurgião-Dentista conheça as características e diferentes abordagens ao portador do transtorno de espectro autista, assim como seus estágios, peculiaridades e nível de dependência dos responsáveis, para melhor atender os pacientes infantis portadores de TEA, com todas as suas individualidades e limitações.
Materialismo histórico e dialético: ferramenta metodológica para a compreensão das relações de produção e poder
Authors: Rodrigues Raimundo Ferreira , Santos Adelma Rodrigues dos , Costa Sérgio Celestino , Araújo Eliane Oliveira Santos , Nepunucena Paulo Pires , Bonfim Maria Catia Eliana Roque , Nascimento Weslane Cirqueira Cavalcante do , Bezerra João Martins , Lima Renan Alves , Fernandes Jacob Ricardo Pereira de Carvalho
Published: October 2024

Este estudo objetiva compreender e apresentar uma análise sobre a metodologia de pesquisa do materialismo histórico e dialético, enfocando sua abordagem crítica. A pesquisa baseia-se em uma revisão bibliográfica de cunho qualitativo. O materialismo histórico e dialético, desenvolvido por Karl Marx e Friedrich Engels, serve como uma metodologia fundamental para a análise crítica das relações sociais e econômicas. Este artigo explora como essa abordagem revela as dinâmicas de poder e contradições inerentes às estruturas capitalistas, oferecendo bases teóricas para transformação social. Os resultados da pesquisa demonstram que a metodologia do materialismo histórico e dialético é eficaz para revelar as contradições e as relações de poder subjacentes nas esferas sociais, econômicas e políticas. Ao aplicar essa abordagem, foi possível compreender como as relações de produção e as lutas de classe moldam o desenvolvimento histórico. Além disso, a análise crítica das fontes, focando nas relações de classe, permitiu uma compreensão mais profunda das condições materiais que influenciam os fenômenos observados. As conclusões apontam que, apesar dos desafios e da complexidade na aplicação do materialismo histórico e dialético, essa metodologia é fundamental para uma análise crítica da realidade social e histórica. A interpretação materialista oferece uma visão abrangente que contribui significativamente para os estudos sociais, revelando as dinâmicas ocultas das estruturas de poder. Assim, a pesquisa reforça a relevância dessa abordagem na análise das condições materiais e sociais que moldam os eventos históricos.
Análise dos fatores relacionados a mortalidade do câncer de cólon em 2022 no Brasil
Authors: Ramos Osmar de Oliveira , Pozzan Gabriel Luís , Silva Marcone Gonçalves , Oliveira Maraisa Finotto de , Rodrigues Marcelo
Published: October 2024

O câncer colorretal (CCR) é um dos principais responsáveis pela mortalidade oncológica em todo o mundo, ocupando o terceiro lugar em incidência global. No Brasil, a mortalidade por câncer de cólon apresenta variações significativas entre as regiões, refletindo disparidades no acesso aos serviços de saúde, diagnóstico precoce e tratamento eficaz. As regiões Sudeste e Sul concentram as maiores taxas de mortalidade, o que ressalta a necessidade de políticas públicas de saúde mais direcionadas para essas áreas. Este estudo tem como objetivo analisar os fatores relacionados à mortalidade por câncer de cólon no Brasil no ano de 2022, focando em variáveis como idade, sexo, fatores de risco comportamentais (tabagismo, consumo de álcool) e presença de comorbidades. A metodologia adotada baseou-se em uma análise transversal de dados do DataSUS, com foco nos registros de mortalidade e nas variáveis associadas. Os resultados indicam que a mortalidade aumenta significativamente com o avanço da idade, e o tabagismo mostrou-se um fator de risco importante, enquanto as comorbidades e o histórico familiar de câncer não tiveram impacto estatisticamente significativo. O estudo enfatiza a importância de intervenções preventivas e personalizadas para melhorar os desfechos clínicos e reduzir a mortalidade por câncer de cólon no Brasil.
Acurácia da elevação do segmento ST para o diagnóstico de oclusão coronariana aguda: uma revisão da literatura
Authors: Moura Anna Clara Lopes de , Marques Bruna Silveira , Gonçalves Tiago Ferreira , Belem Bernardo Lemos Monteiro , Dourado Vinícius dos Santos , Moreira Humberto Graner
Published: October 2024

A Oclusão Coronária Aguda (OCA) consiste em um quadro grave de obstrução do fluxo sanguíneo para os cardiomiócitos, que resulta em isquemia e necrose, sendo recomendada a realização de terapia de reperfusão imediata. Nos últimos anos, consolidou-se o entendimento de que em casos de infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAMCSST) a reperfusão emergencial traria melhorias no desfecho cardiovascular. Logo, o achado no eletrocardiograma (ECG) passou a ser associado à OCA, tornando-se necessária a investigação de sua acurácia diagnóstica, bem como da pertinência do paradigma IAMCSST-IAMSSST. Trata-se de uma revisão integrativa, na qual realizou-se uma busca nas bases de dados Pubmed e Embase, orientada pelos descritores “Coronary Occlusion” AND “Electrocardiography” AND “ST Elevation Myocardial Infarction”. Seis estudos foram incluídos nesta revisão. A literatura aponta que o enfoque isolado em achados do ECG pode negligenciar a precisão diagnóstica de OCA, já que a elevação do segmento ST (EST), apesar de ser altamente específica (96,5%), tem sensibilidade de 43,6%. Ademais, na população em geral, tem-se que 65 a 85% dos pacientes com padrão eletrocardiográfico de IAMCSST têm, de fato, um quadro de OCA. Contudo, ao restringir essa análise a achados específicos, essa proporção pode diminuir. Logo, avalia-se que a EST apresenta sensibilidade diagnóstica limitada e, apesar de ser útil na triagem precoce, deve ser reavaliada como parâmetro determinante do diagnóstico, posto que a fisiopatologia da oclusão deve ser considerada como processo primário do infarto, otimizando o manejo e o desfecho de pacientes.
Características das populações celulares e condições do microambiente tumoral do câncer pancreático e sua importância no estadiamento clínico
Authors: Morais Mariana Ramos de , Martins Maria Alice Chagas , Dourado Vinícius dos Santos , Brandão Elymar Santana , Boareto Lucas Xavier , Cassão Bruna Dell’Acqua
Published: October 2024

O adenocarcinoma pancreático é altamente letal devido à sua rápida progressão e resistência à quimioterapia e radioterapia. Estudos recentes destacam a necessidade de novas abordagens terapêuticas que considerem tanto as características celulares quanto o microambiente tumoral. A transição epitélio-mesenquimal (EMT) é crucial na progressão e invasão do câncer, com o marcador Snai2 sendo significativo para subtipos mais agressivos. Além disso, o microambiente tumoral, incluindo a infiltração de macrófagos e inflamação, desempenha um papel essencial na progressão do tumor. Marcadores como CD73 e PD-L1, estão associados a um pior prognóstico e resistência à terapia. A diversidade microbiana também influencia os resultados clínicos, sugerindo que sua modulação pode ser uma estratégia terapêutica adicional. Células-tronco cancerígenas pancreáticas (PCSCs) e a modulação de metilação m6A são críticas na progressão e resistência à terapia. A compreensão dessas interações é fundamental para prever o prognóstico e desenvolver novas estratégias de tratamento. A influência da hipóxia tumoral no microambiente imunológico, revelando que altos níveis de hipóxia estão associados a um pior prognóstico e resposta imunológica comprometida. Essas descobertas sugerem que a combinação de terapias que visam marcadores como CD73 e PD-L1, junto com a modulação do microambiente tumoral, pode oferecer abordagens mais eficazes para o tratamento do adenocarcinoma pancreático.
FORMATION OF INVESTMENT ACTIVITY IN THE REGION AS A FACTOR OF SPATIAL DEVELOPMENT
Authors:   M.Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan, Raimbekova U.К.
Published: October 2024

Capital is always looking for favorable conditions to preserve and increase, respectively, the institutional factors of investment activity in the regions of the country are crucial to ensure its attraction. The purpose of this study is to substantiate the impact of investments on the main economic indicators of the region's development, on its spatial development. The article examines the importance and role of investments and provides a brief overview of scientific ideas about the content of the concept of «spatial development. It is shown that when developing a spatial development strategy, it is necessary to apply a systematic approach. During the research, general scientific methods of analysis and special methods of economic and statistical research were used. From the results obtained, it can be concluded that the state of investment activity in the region has unstable growth trends, in particular investments in fixed assets. In conclusion, the main aspects of the relationship between investment activity and the spatial development of the region are summarized.
PROBLEMS OF SOCIAL INTEGRATION OF FOREIGN STUDENTS IN UNIVERSITIES OF KAZAKHSTAN
Authors:   M.Kh. Dulaty Taraz State Universit, Taraz, Kazakhstan, Mordvintseva I.Y. , Antonov A.A. ,   M.Kh. Dulaty Taraz State Universit, Taraz, Kazakhstan
Published: October 2024

This work examines the problem of social integration of international students. The work analyzes scientific sources, as well as psychological and pedagogical literature, and assesses the level of social integration of students, which should be taken into account in the process of their communication and study. The definitions of "social adaptation" are disclosed in the article. The author conducts an anonymous survey using an online platform to identify the problems that foreign students face in the process of social adaptation, and draws conclusions about the factors that have an exact impact on the integration of students in domestic universities.The article notes the positive effect that co-education of foreign students with domestic students has on the development of the status of a higher educational institution, as well as on a deeper understanding by foreign students of the values of the environment in which they have immersed themselves. It should be noted that the author of the article emphasizes that the involvement of foreign students in the educational and educational process develops their personalities as full-fledged members of the society of the country in which they study at a higher educational institution.
THE ROLE OF THE TEACHER IN THE DEVELOPMENT OF FACT-CHECKING SKILLS IN 7TH GRADE STUDENTS STUDYING CHEMISTRY
Authors:   M. Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan, Kambarova E.A. , Yussupova Kh.A. ,   M. Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan, Bauyrzhankyzy A.B. ,   M. Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan, Ismailova R.A. ,   M. Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan
Published: October 2024

This article examines the role of a teacher in the formation of fact-checking skills among schoolchildren in the context of their training in chemistry. In the era of the modern information society, where access to a huge amount of information is easily accessible, the ability to analyze and verify facts becomes absolutely critical. This article discusses a variety of methods that teachers can use to integrate fact-checking into their curricula. These methods include the development of lessons aimed at assessing the reliability of sources, the analysis of experimental data and a critical review of the literature. Teachers, paying attention to examples of unreliable information in chemical publications, can encourage students to develop skills of critical evaluation of information. The article focuses on the practical aspects of teaching fact-checking, including the use of modern technologies and online resources to verify the validity of facts. The study highlights the need for constant updating of teaching methods to meet the changing information environment. The development of fact-checking skills among schoolchildren not only contributes to their successful education in the field of chemistry, but also helps to form the foundations of critical thinking and responsible information consumption.
THE INFLUENCE OF MUSIC ON THE EMOTIONAL STATE OF STUDENTS: SOCIOLOGICAL ANALYSIS
Authors:   Zhetysu University named after I. Zhansugurov,Taldykorgan, Kazakhstan, Mirzakulova G. A.
Published: October 2024

Music plays a huge role in the everyday life of today's society,especially for schoolchildren. Music is not only a form of self-expression, it also has a profound effect on the emotional state. In this regard, the problem of the influence of music on the emotional stability of adolescents shows its great relevance. If there is emotional stability, then society has its own impact on the quality of life and personal development. The development strategy "Kazakhstan-2030" enshrines the goal of developing the quality of life of the population, including the formation of the condition of adolescents and children. Therefore, the study of this issue makes it possible to understand the full impact of cultural aspects such as music on the mental well-being of adolescents and then apply them appropriately. The purpose of the study is to identify and analyze the influence of music on the emotional state of students. Determining which genre of music and which elements have the most emotional effect on adolescents.
FORMATION OF THE DESIRE OF PRIMARY SCHOOL STUDENTS TO ACQUIRE KNOWLEDGE ON A PRODUCTIVE BASIS IN MATHEMATICS LESSONS
Authors:   M. Kh. Dulaty Taraz Regional University, Taraz, Kazakhstan, Kenzhebaeva A.T.
Published: October 2024

The article "Formation of the desire of primary school students in mathematics lessons to acquire knowledge on a productive basis" is devoted to the urgent problem of forming the necessary competencies, skills and abilities for productive educational activities in primary school students. The author of the work gives a detailed analysis of the teacher's work in the initial level. Emphasizing the rather large proportion of reproductive methods in the educational process, the author will raise questions about the need for a creative approach to working conditions with younger schoolchildren in order to awaken and form students' desire to study mathematics. At the same time, in the author's opinion, it is necessary to intelligently combine traditional and innovative technologies, which form students' cognitive activity, independence in finding optimal solutions, and the desire to make their own discoveries. These types of work should be carried out taking into account the age characteristics of children and on a systematic basis. The most effective, in the author's opinion, are health-saving technologies, gaming, case technologies, etc.
Source localization of mu-rhythm event related desynchronization in EEG during tactile imagery
Authors: Yakovlev L. V. , Syrov N. V. , Miroshnikov A. A. , Morozova M. V. , Berkmush-Antipova A. M. , Petrova D. A. , Kaplan A. Y.
Published: October 2024

Tactile imagery remains a relatively understudied phenomenon in the field of mental imagery research. However, alongside motor imagery, this technique holds promise as an effective tool for sensorimotor rehabilitation following stroke and spinal cord injuries. In this study, conducted with 22 healthy volunteers, we investigated the source localization of mu-rhythm event related desynchronization (Event-Related Desynchronization, ERD) using multi-channel electroencephalogram recordings and subsequent inverse problem solution with the sLORETA method. All participants exhibited ERD during tactile imagery task, as well as under vibrotactile stimulation. It was demonstrated that mu-rhythm ERD during vibrotactile stimulation, as well as tactile imagery, was localized in the sensorimotor areas of the contralateral hemisphere. Within the source space, ERD in the postcentral gyrus was significantly stronger compared to the precentral gyrus. These findings indicate that tactile imagery, akin to the perception of real tactile stimuli, leads to prominent activation of sensorimotor cortical areas, consistent with the general understanding of the shared neural substrate during mental imagery and perception.
Hukum Ketenaganukliran di Indonesia
Authors: Hiswara Eri , Darmawati Suzie
Published: October 2024

Selain bermanfaat untuk meningkatkan kesejahteraan manusia, aplikasi ilmu pengetahuan dan teknologi (iptek) nuklir atau radiasi juga diketahui memiliki risiko bahaya bagi kesehatan. Karena itu, pemanfaatan radiasi perlu dilakukan dengan pengawasan yang ketat, salah satunya dengan membuat peraturan agar aplikasinya tidak menghasilkan dampak bagi keselamatan dan kesehatan baik bagi pekerja, pasien, maupun masyarakat umum. Di Indonesia, Undang-Undang Nomor 10 Tahun 1997 merupakan peraturan tertinggi terkait ketanaganukliran, yang kemudian diatur lebih lanjut oleh beberapa peraturan pemerintah, dan aturan pelaksanaannya ditetapkan oleh Badan Pengawas Tenaga Nuklir (BAPETEN).
Dalam buku ini diuraikan beberapa peraturan pemerintah dan Peraturan BAPETEN yang relevan dan dibagi atas beberapa subjek yang menjadi dasar dalam pemanfaatan tenaga nuklir, yaitu badan pengawas, perizinan, pengendalian impor dan ekspor, pengecualian dan klierens, keselamatan dan keamanan radiasi, keselamatan dan keamanan nuklir, inspeksi dan safeguards, keselamatan pengangkutan bahan radioaktif, pengelolaan limbah radioaktif dan bahan bakar nuklir bekas, kesiapsiagaan dan tanggap darurat nuklir, dan pertanggungjawaban kerugian nuklir.
Setelah membaca buku ini pembaca diharapkan dapat memahami peraturan ketenaganukliran di Indonesia secara komprehensif. Pemahaman ini diharapkan dapat membantu dalam mewujudkan sistem dan peraturan ketenaganukliran di Indonesia yang lebih efektif sesuai dengan kebutuhan dan perkembangan iptek ketenaganukliran yang ada.
Digital Revolution and Artificial Intelligence as Challenges for Today/Rewolucja cyfrowa i sztuczna inteligencja jako wyzwania współczesności
Authors: Marsili Marco , Wróblewska-Jachna Joanna
Published: October 2024

This article addresses the social impact of the ongoing digital revolution through a critical analysis of the literature on the subject. The aim is to understand the dynamics of change, which is key to dealing with the complexities of the digital age and realising its potential for sustainable development. The information revolution and artificial intelligence pose significant challenges to modern society by marking a profound transformation through self-organising social changes that disrupt existing norms. The digital age has revolutionized information systems, much like Gutenberg's invention of movable-type printing press. While it enables scientific and economic progress, the information revolution raises ethical, moral and legal concerns. Social media have become ”weapons” in a hybrid conflict, where the intangible battleground is human cognitive systems.
On the need for integrating social sciences and engineering – technical disciplines in studying contemporary social phenomena. New directions in digital sociology/O potrzebie integracji nauk społecznych i dyscyplin inżynieryjno-technicznych w badaniu współczesnych zjawisk społecznych. Nowe kierunki w socjologii cyfrowej
Authors: Dyczek Berenika
Published: October 2024

The main aim of this article is to emphasize the significance of adopting an interdisciplinary approach when researching contemporary social phenomena. It identifies the shortcomings of traditional sociology, which frequently lacks the digital tools to effectively analyse these phenomena, and contrasts them with engineering approaches that frequently employ computer science methods. This article advocates for a combination of these disciplines, which not only promotes the development of innovative methods but also contributes to the emergence of sub-disciplines such as Digital Sociology, Computational Social Science, and Digital Social Science. The argument presented is grounded in Actor-Network Theory (ANT), which provides a robust framework for understanding the dynamic interplay between society and technology, acknowledging both human and non-human entities as active participants in social networks. This approach challenges traditional perspectives and encourages a comprehensive reassessment of social interactions and technological impacts.