bluuebunny/crossref_metadata_2025 huggingface dataset:
A Systematic Review of EEG/ERP Studies on Verbal Irony Processing
Authors: Du Yiran , Jia Kunjie
Published: November 2024

This systematic review examines the neural processing of verbal irony as revealed by event-related potential (ERP) studies using electroencephalography (EEG). Verbal irony processing involves complex cognitive mechanisms, represented in ERP components, particularly the N400, P600, and Late Positive Component (LPC). Synthesizing findings from 22 studies, this review explores how language, age, clinical status, and modality (auditory, visual, multimodal) influence ERP effects during irony comprehension. Results reveal that modality significantly impacts ERP responses, with auditory presentations often eliciting robust N400 effects linked to rapid semantic integration, while visual presentations frequently engage both N400 and P600/LPC, suggesting extended reanalysis. Multimodal approaches combining auditory and visual cues show increased cognitive demands, indicated by complex ERP patterns. Across studies, the N400 component and N400-like activity appear in 50% of cases, marking semantic incongruity, while the P600/LPC component, observed in 77.3% of studies, reflects reanalysis during irony comprehension. This review underscores the role of modality in shaping the neural correlates of irony processing and highlights areas for future research, including demographic diversity and the integration of ERP with other neuroimaging techniques.
Holes are perceived as proto-objects with limited properties: Subitizing holes and hole-specific preview benefits
Authors: Liu Fuju , Hu Qingfen
Published: November 2024

Holes appear to be non-material entities that nonetheless resemble ordinary objects in many aspects. Whether to accept this as the ontological reality of holes and what the alternatives might be present challenges for philosophical reflections. Taking an epistemic approach exemplified by previous work on shapes of holes, we ask why this puzzle of holes arises in the first place by exploring whether holes are objects in terms of visual processing. Specifically, we tested how the FINST mechanism and the object file system treat holes. Experiment 1 found subitizing of holes that was nearly identical to that of matched discs. Experiment 2 tested object-specific preview benefit (OSPB) on holes, i.e. HSPB, finding no evidence of it. Experiment 3 eliminated two confounding factors but still found no reliable HSPB. Experiment 4 confirmed a prediction, suggesting that while holes do not activate representations comparable to object files, their movements can be tracked to support the computation of object correspondence, producing an anomalous preview benefit. Therefore, holes are treated similarly to ordinary objects in terms of visual individuation by the FINST mechanism, but unlike object files, there may not be hole files that bind arbitrary properties to holes. Together with previous studies on visual perception of holes, these results suggest that beliefs about holes—whether they are considered objects or not—have their origins in vision. The puzzle of holes may not necessarily be ontological but epistemic, arising from attempts to reconcile outputs from visual processes governed by different functioning principles.
Long-term lifetime trends of large appliances since the introduction in Norwegian households
Authors: Krych Kamila , Pettersen Johan Berg
Published: November 2024

Longer lifetimes of consumer products are promoted as an element of sustainable consumption, yet there is a widespread notion that lifetimes are currently in decline, often attributed to planned obsolescence or throwaway mentality. However, empirical evidence is inconclusive and often subject to high uncertainties. Here, we explore long-term trends in the lifetimes of large household appliances using dynamic material flow analysis (dMFA). We investigate the sales and ownership of these products since their introduction in Norwegian households and use this co-evolution to estimate the lifetimes. By combining two model types with uncertainty analysis, we show that a significant lifetime decrease was likely experienced only by washing machines (-45%) and ovens (-39%) around the 1990s-2000s. This finding challenges the narratives about planned obsolescence despite their prevalence decreasing consumer incentives for longer product use and repair. We suggest multiple technical, economic, and social factors that could be responsible for the decrease, e.g., a reduction in relative prices of appliances or changes in habits surrounding laundry and kitchen use. Our results suggest that factors affecting product lifetimes are not uniform but context-dependent, which has implications for lifetime extension policy. The presented method could help monitor the long-term effectiveness of such policy.
An Overview Of TWIP Steels And Their Suitability For Automotive Manufacturing
Authors: Felix Bernard
Published: November 2024

Twinning-induced plasticity steels have gained significant attention in the automotive industry due to their exceptional blend of high strength and ductility. Extensive research has investigated their alloy composition, microstructure, mechanical properties, and simulations. This article explores the characteristic composition, microstructure, primary deformation and strengthening mechanisms, and distinctive mechanical properties of TWIP steels that make them suitable for automotive manufacturing, drawing from numerous professional publications. Additionally, it examines how key alloying elements, such as aluminum and manganese, impact the microstructure and mechanical performance of TWIP steels. The applications of TWIP steels in automotive components, including body structures, are also discussed.
Neurological and Behavioural Correlates of Construal in Economic Decision-Making Under Cognitive Load.
Authors: Wilson Christopher James
Published: November 2024

Construal level has been shown to influence economic decisions, affecting both risk perception and risk-taking. However, there has been some inconsistency as to the exact effects of high/low construal on economic decisions, with some findings suggesting that construal might interact with cognitive load and self-control in a risk-taking context. In two experiments, the current paper examines behavioural and neurological (using functional near-infrared spectroscopy) responses to high and low construal manipulations during and economic decision task, under experimentally-induced cognitive load. We also examine the how construal interacts with self-control, financial literacy and subjective numeracy to predict lateral pre-frontal cortex (LPFC) activation during these decisions. Some of the behavioural results supported previous findings that under cognitive load, high construal prompts risk aversion. Neurological data supported the theory that construal promotes risk sensitivity. Self-control, financial literacy and subjective numeracy were all found to interact with construal in predicting LPFC activation during decision-making. These findings extend our understanding of how construal effects economic decisions under cognitive load while also providing new insights into how self-control, financial literacy and subjective numeracy might interact with construal in this context.
Life, the Observer, and Consciousness
Authors: Stefan C.
Published: November 2024

I will try to summarize and define an integrative ecological and phenomenological view about life and consciousness. I will assume and argue, on a personal account and through scientific grounds in the favor of significant atomic units of meaning and with that, through a re-positioned perspective, I will conceptualize and explain a common meaning-making place and space. A space which – as it was already more or less formally tackled by our most notable philosophers, scientists, artists and spiritual practitioners since millennia – it seems to represent, as we shall see, the essential drive within the human space and the natural world. In the explanatory “gap” for life I would re-visit that “soft but powerful” space and dare to re-conceptualize it and see it through the lens of a unifying and holistic perspective. I will show what it consists of, what it holds and upholds, and how it can be defined and computationally, quantitatively and by structural modeling means, approachable. Sustained by that background, and through the specific mechanisms as identified and expressed in this thesis, I would extrapolate and boldly cast an analog space as specific to life forms or systems satisfying the defined criteria. Through that, I would see a new perspective through which it seems I can dissolve – or at least narrow the view in the forms of “hard problems” of consciousness. This holistic view, as strongly re-framed within the broad ecological situatedness, seems to cast a new perspective over life forms, observer instances and phenomenological dimensions and indeed, be able to explain how life and we, seem to function in a self-contained and self-sufficient way. Through that view, and through the core principles and working assumptions assumed – themselves coming along more than two decades of non-frontal and exploratory thinking practice – a new framework would develop as first principles for further research in strong-AI domain – the main reason for the whole enterprise as it was developing around: if and how machines would be able to think the way humans do.
ADMINISTRATION OF TAX BENEFITS BY THE TAX AUTHORITIES OF THE RUSSIAN FEDERATION
Authors:   Kuban State University, TSORIONOV V.V.
Published: November 2024

Tax authorities act as the main conductors of the fiscal function of the modern state. Realizing their powers, they contribute to the economic and social development of public and legal entities, prevent, detect and suppress tax offenses, as well as participate in ensuring the balance of public and private interests, including in the process of administration of various tax benefits.The purpose of the study is to determine the content of the powers of the Federal Tax Service of Russia and its territorial subdivisions in the administration of tax benefits at the current stage of development of tax legislation. The main methods of research were general scientific methods of cognition (analysis and synthesis, generalization and analogy), philosophical method of dialectical cognition, special methods of technicallegal and comparative-legal analysis. As a result of the study, it was established that the administration of tax benefits by the Federal Tax Service of Russia and its territorial bodies includes: 1) powers to administer the introduction of benefits by state authorities and local governments; 2) powers to administer the realization of the right to benefits belonging to taxpayers. In their totality, these groups of powers are aimed at ensuring the balance of private and public interests in the formation of centralized funds of the state and its territories.
INHERITANCE OF LAND PLOTS ACCORDING TO THE LEGISLATION OF THE RUSSIAN FEDERATION AND FOREIGN COUNTRIES: COMPARATIVE LEGAL ANALYSIS
Authors:   Kuban State University, ELISEEVA I.A.
Published: November 2024

The purpose of this article is to study the features of inheritance of land plots in the Russian Federation, as well as to conduct a comparative analysis of inheritance of land plots in domestic legislation and legislation of foreign countries. This is important for improving Russian legislation regulating these public relations. In order to achieve these goals, it seems necessary to study the Russian scientific doctrine on inheritance of land plots, the current Russian legislation, conduct a comparative analysis of Russian and foreign legislation in this area, identify shortcomings and positive experience in the legislative regulation of hereditary land relations in the Russian Federation and foreign countries.The purpose and objectives of the work determined the methodology of this study, which is based on a number of methods, in particular: comparative legal, formal logical, dialectical method of cognition of social phenomena and processes. As a result of the conducted research, the author has formulated a number of conclusions, as well as some recommendations regarding the improvement of Russian legislation in this area. In particular, the provision established in the legislation of the countries of the German group, according to which the testator does not have the right to arbitrarily bequeath his land property (land and real estate located on it), seems justified. The property must pass to one of the heirs of the deceased, and the rest have the right to claim property compensation from the heir. If this is an agricultural land plot, then the following criteria must be used when choosing an heir: the heir must be closely associated with farming on it, have appropriate qualifications, work experience in agriculture and the ability to effectively farm. From this point of view, the French principle of «preferential valuation of agricultural land» is also attractive, according to which the court must elect the most qualified heir among all. At the same time, the payment of financial compensation to the remaining co-heirs places a financial burden on the farm, but its term in French law is long (ten years). We propose to amend the Russian legislation accordingly, increasing the period of payment of appropriate compensation to at least three years. Thus, we recommend introducing some novelties into Russian legislation, taking into account foreign experience in regulating hereditary land relations, which, it seems, will contribute to improving legal regulation in this area.
Effect of Spray Adjuvant and Prohexadione Calcium Formulation on Peanut (Arachis hypogaea L.) Productivity
Authors: Song Yangyang , Monfort W. Scott , Warren Savannah , Towles Tyler , Scruggs Jim , Zurweller Brendan
Published: November 2024

Prohexadione calcium (calcium 3-oxido-5-oxo-4-propionylcyclohex-3-enecarboxylate) is used to manage excessive vegetative growth in peanut (Arachis hypogaea L.). This practice has traditionally been more widespread in Virginia market-type cultivars that generally have more vigorous canopy growth. However, the use of this active ingredient in runner peanut cultivation continues to increase. Prohexadione calcium was initially formulated as a water dispersible granule (WDG) and a new oil dispersion (OD) formulation has been introduced. Limited information is available regarding optimal adjuvants and application rates for the OD formulation of prohexadione calcium. This study aims to assess the efficacy of the new OD formulation of prohexadione calcium on pod yield, grade and economic return. Six experiments were conducted across locations in Mississippi and Georgia in 2022. The findings indicate that the OD formulation yields similar effects in managing excessive vine growth when using either crop oil concentrate or non-ionic surfactant adjuvants, thereby resulting in comparable yield, grade, and economic return to that of the WDG formulation. Moreover, prohexadione calcium exhibits the capacity to suppress excessive vegetative growth and enhance pod yield at reduced application rates, specifically at105 g ai/ha. This reduction in application rate, coupled with the improvement in yield, translated into a higher return on investment, ranging from 30 to 400 U.S. dollars per hectare, across three out of four experimental sites when compared to the non-treated control. These results suggest that profitability could be increased by applying prohexadione calcium on runner peanuts if excessive vine growth occurs.
Introduction
Authors: Jarausch Konrad H.
Published: November 2024

This article is an introduction to the Zeitenwende discussion regarding Chancellor Olaf Scholz's announcement of a turning point of German foreign policy in response to the Russian invasion of Ukraine. After explaining the concept, the text reviews the prior tradition of a “civilian power” and explores the military and economic dimensions of Berlin's “policy reversal.” The article then probes the conflicted “public responses” and discusses the “implementation problems” in order to assess the efficacy of the change of course. The evaluation concludes with some comments on the “future prospects” of Germany's role in what has turned into a lengthy war of attrition.
Dobre imię – wizerunek – prywatność. Aktualne problemy ochrony dóbr osobistych na tle orzecznictwa sądowego
Authors: Herbert Andrzej
Published: November 2024

Znaczenie ochrony dóbr osobistych takich jak: życie, zdrowie, nietykalność cielesna, wolność, swoboda sumienia, cześć i dobre imię, nazwisko i pseudonim, wizerunek, tajemnica korespondencji, nietykalność mieszkania - obecnie wzrasta, zarówno z teoretycznego i praktycznego punktu widzenia. Rozwój doktryny i orzecznictwa wykazuje w tym zakresie rzadko spotykaną w innych obszarach prawa cywilnego dynamikę, oraz że wskazana tendencja utrzyma się także w przyszłości. Co jednak najbardziej charakterystyczne, motorem tych zmian jest w ogromnej części orzecznictwo, które aktywnie wykorzystuje dorobek nauki prawa, dostosowując zakres i standard ochrony do zmieniających się warunków społecznych i gospodarczych.
Analiza zagrożeń wynikających ze stanu środowiska w Polsce - ochrona gleb
Authors: Resztak Ilona
Published: November 2024

W niniejszym artykule autor podejmuje rozważania dotyczące analizy zagrożeń wynikających ze stanu środowiska w Polsce oraz ochrony gleb. Wskazuję również iż instrumenty prawne dotyczące ochrony powierzchni ziemi są mało spójne. Jednak najważniejsze znaczenie odgrywa ustawa Prawo ochrony środowiska, która przedstawia ogólne cele ochrony powierzchni ziemi, oraz odsyła do innych aktów prawnych m.in. miejscowego planu zagospodarowania przestrzennego oraz planu gospodarowania na zdegradowanych gruntach, a także środków reglamentacyjnych ograniczających dostępność korzystania z powierzchni ziemi jak np. standardy jakości gleby, decyzje rekultywacyjną, zgodę na zmianę przeznaczenia gruntów oraz zezwolenia na wyłączenie gruntów z produkcji, a także do ustawy o ochronie gruntów rolnych i leśnych, ustawy o planowaniu i zagospodarowaniu przestrzennym oraz innych.
Dwadzieścia lat obecności Polski w Unii Europejskiej. Analiza ekonomiczna rozwoju gospodarczego na tle gospodarki niemieckiej
Authors: Papka Karol , Kubicki Damian
Published: November 2024

Na przestrzeni ostatnich 20 lat gospodarka Polski doświadczyła spektakularnego rozwoju. Modernizacja infrastruktury oraz napływ środków unijnych pobudziły wzrost gospodarczy Polski. Nieustannie unowocześniana struktura gospodarcza kraju daje nadzieję na kontynuację procesu nadrabiania zaległości wynikających z okresu Polskiej Rzeczpospolitej Ludowej. Przedmiotem niniejszej pracy jest analiza porównawcza rozwoju gospodarczego osiągniętego przez Polskę na tle gospodarki niemieckiej w okresie ostatnich dwóch dekad. Przeprowadzona analiza opiera się na kluczowych wskaźnikach gospodarczych, tj. PKB w ujęciu realnym i nominalnym oraz PKB per capita według parytetu siły nabywczej, które umożliwiają ocenę sytuacji makroekonomicznej. Dopełniając przeprowadzone badania, scharakteryzowano zmiany, które zaszły w strukturach gospodarczych obu państw, będące efektem transformacji postindustrialnej. Dodatkowo autorzy podjęli próbę ukazania, jak z ekonomicznego punktu widzenia oba państwa prezentują się na tle pozostałych państw Unii Europejskiej.
Феномен Иуды Искариота (по повести Л. Н. Андреева «Иуда Искариот»)
Authors: Денис Владимирович Макаров
Published: November 2024

Цель статьи — рассмотреть историю создания, литературные и философские истоки, сюжет, образносимволическую систему повести Леонида Николаевича Андреева «Иуда Искариот» и выявить художественные особенности образа Иуды, авторскую концепцию человека в евангельском контексте на материале данного произведения. Основу методологии исследования составляет системный подход к анализу поэтики художественного произведения в контексте православной культурной традиции. Исследуются сюжет, мотивы, образы, символика повести и предпринимается попытка выявления авторской концепции человека на данном материале.

The purpose of the article is to examine the history of creation, literary and philosophical origins, plot, figurative and symbolic system of the novel by Leonid Nikolaevich Andreev «Judas Iscariot» and to identify the artistic features of the image of Judas, the author’s concept of man in the evangelical context based on the material of this work. The basis of the research methodology is a systematic approach to the analysis of the poetics of a work of art in the context of the Orthodox cultural tradition. The plot, motives, images, and symbolism of the story are investigated and an attempt is made to identify the author’s concept of a person based on this material.
Житие Зосимы и Савватия Соловецких чудотворцев для Косинского монастыря: источники текста
Authors: Павел Анатольевич Тарасенко
Published: November 2024

Статья посвящена изучению Косинской редакции Жития преподобных Зосимы и Савватия Соловецких чудотворцев. В работе намечаются пути выявления всех источников текста, рассматриваются принципы работы редактора текста, новгородского книжника Бориса Козынина.

The article is devoted to the study of the Kosinsky edition of the Vitae of the Venerable Zosimas and Sabbatius, the Solovetsky miracle-workers. It describes the methods for identifying all sources of the text and describes the editing principles used by the Novgorod scribe Boris Kozynin.
Духовно-религиозные аспекты семантики открытого финала (на материале произведений Ф. М. Достоевского и К. С. Льюиса)
Authors: Ирина Алексеевна Павлова
Published: November 2024

В статье рассматривается аксиологический подход к исследованию литературного произведения. Целью такого подхода является обнаружение связей между поэтикой художественного текста и нравственными ценностями, которые могут быть обнаружены внутри созданного автором мира. Предметом исследования стал феномен открытого финала в романах Ф. М. Достоевского. Наблюдения над сюжетом романа «Преступление и наказание» показывают, как автор сознательно отказывается от роли всеведущего Творца, оставляя больше места для действия Духа в том мире, который возникает в художественном произведении. Это проявляется в том, что момент откровения, после которого произошёл коренной перелом в жизни главного героя, остаётся тайной, которую автор не берётся описывать. Использование открытого финала позволяет также создать героя, наделённого бессмертной душой и свободной волей, так как всякое «последнее слово» о нём выходит за рамки внутреннего пространства художественного произведения, в котором находится герой, и является либо голосом автора, либо голосом некой Высшей Силы, производящей суд над героем, и передаваемой тем же автором. Закрытый финал последнего типа характерен для произведений К. С. Льюиса. Анализ композиции и архитектоники романов Ф. М. Достоевского и К. С. Льюиса позволяет сделать выводы о структурной и идейно-проблематической специфике открытого финала в романе.

The article considers an axiological approach to the study of a literary work. Such an approach has the purpose of discovering the connections between the poetics of a literary text and the moral values that can be found inside the world which was created by the author. The subject of the study is the phenomenon of the open ending in the novels of F. M. Dostoevsky. Observations on the plot of the novel «Crime and Punishment» show how the author consciously renounces the role of an omniscient Creator, leaving more room for the action of the Spirit in the fictional world of the book. It is manifested in the fact that the moment of revelation, after which there is a radical change in the life of the main character, remains a mystery that the author does not undertake to describe. The use of an open ending also allows you to create a hero endowed with an immortal soul and free will, since every «last word» about him goes beyond the inner space of the work of art in which the hero is located and is either the voice of the author or the voice of some Higher Power that judges the hero and is transmitted by the same author. The closed finale of the latter type is typical for the works of C. S. Lewis. The analysis of the composition and architectonics of the novels by F. M. Dostoevsky and C. S. Lewis allows us to make conclusions about the structural and ideological-problematic specifics of the open ending in a novel.
Особенности подготовки гимнографического текста: трудности герменевтического и лингвистического порядка
Authors: И. В. Ерохина
Published: November 2024

Настоящая статья посвящена раскрытию особенностей подготовки гимнографического текста «Служба новомученику Юрию Петроградскому (Новицкому)» для канонизации текста в Синодальной богослужебной комиссии. При написании новых гимнографических текстов необходимо учитывать многовековой опыт Русской Православной Церкви, а также лингвистические особенности церковнославянского языка для правильного построения выражений притчевых богослужебных молитвословий. Обращаясь к святоотеческому наследию, автор статьи предлагает с помощью герменевтического подхода проанализировать новонаписанный гимнографический текст.

The present article reveals the peculiarities of preparing the hymnographic text of the «Service to the New Martyr Yuri of Petrograd (Novitsky)» for its canonization by the Synodal Liturgical Commission. When writing new hymnographic texts, it is necessary to take into account the centuries-old experience of the Russian Orthodox Church, as well as the linguistic peculiarities of the Church Slavonic language for the correct construction of the expressions of parable li- turgical prayers. Turning to the holy theological heritage, the author of the article proposes to analyze the newly written hymnographic text using a hermeneutical approach.
Художественная рецепция молитвы «Отче наш…» в лирике В. К. Кюхельбекера
Authors: Андрей Анатольевич Умрилов
Published: November 2024

В русской культуре XIX века молитва «Отче наш…» являлась важнейшим текстом не только религиозного, но и художественного дискурса. Одним из авторов, обратившихся к поэтическому диалогу с молитвой Господней, был В. К. Кюхельбекер. Стихотворное переложение молитвы Господней Кюхельбекер осуществил в 1832 году, включив его в свою тетрадь «Духовных стихотворений». Изучение рецепции канонического текста молитвы «Отче наш…» в творчестве В. К. Кюхельбекера позволяет уточнить не только представления о жанровотематическом диапазоне его лирики, но и о его религиозной картине мира, в центре которой — отношения Бога с человеком, осмысленные как отношения отца с детьми.

In the Russian culture of the XIX century, the prayer «Our Father…» was the most important text not only of religious, but also of artistic discourse. One of the authors who turned to the poetic dialogue with the Lord’s Prayer was V. K. Küchelbecker. Küchelbecker made a poetic arrangement of the Lord’s prayer in 1832, including it in his notebook of «Spiritual Poems». The study of the canonical text of the prayer «Our Father…» in the works of V. K. Küchelbecker makes it possible to clarify not only the ideas about the genre-thematic range of his lyrics, but also about his religious picture of the world, in the center of which is the relationship of God with man, understood as the relationship of a father with children.
Житие святых мучеников Ацискла и Виктории Кордувийских: ценность агиографической литературы в контексте миссионерского служения
Authors: Денис Юрьевич Куприченков
Published: November 2024

Миссионерское служение как проповедь неповрежденного учения Церкви занимает одно из ключевых мест в деле сообщения социуму непреходящих истин и вечных ценностей, которые могли бы существенным образом способствовать решению ряда проблем мировоззренческого характера. В данном ключе житие свв. мчч. Ацискла и Виктории Кордувийских рассматривается в качестве важного звена в диалоге восточной и западной культур и компонента миссиологии, содержащего вероучительные принципы и нравственные имеративы. Специфика агиографической литературы заключается в репрезентации системы духовнонравственных ценностей в масштабе личных качеств конкретного святого, изображаемого через христоцентрическую модель осмысления действительности, исповедание Триединого Бога в качестве ценности совершенной и абсолютной, призвание человека к богоуподоблению. Рассматриваемое житие иллюстрирует важность решения свободно руководствоваться совокупностью базовых христианских ценностей и на их основе осуществлять течение жизни. Представленная статья будет полезна специалистам по истории Церкви, догматическому и нравственному богословию, филологии и культурологии.

Missionary service as the preaching of the intact teaching of the Church occupies one of the key places in the communication of eternal truths and eternal values to society, which could significantly contribute to solving a number of ideological problems. In this context, the lives of the holy martyrs Acisclus and Victoria of Cordova are considered as an important link in the dialogue of Eastern and Western cultures and a component of missiology containing doctrinal principles and moral imeratives. The specificity of hagiographic literature lies in the representation of the system of spiritual and moral values on the scale of the personal qualities of a particular saint, depicted through a christocentric model of understanding reality, the confession of the Triune God as a perfect and absolute value, the vocation of a person to godlike. The life in question illustrates the importance of the decision to be freely guided by the totality of basic Christian values and to carry out the course of life on their basis. The presented article will be useful to specialists in the history of the Church, dogmatic and moral theology, philology and cultural studies.
The cohesin complex: structure and principles of interaction with dna
Authors: Golov A. K. , Gavrilov A. A.
Published: November 2024

Accurate duplication and separation of long linear genomic DNA molecules is associated with a number of purely mechanical problems. SMC complexes are key components of the cellular machinery that ensures decatenation of sister chromosomes and compaction of genomic DNA during division. Cohesin, one of the essential eukaryotic SMC complexes, has a typical ring structure with intersubunit pore through which DNA molecules can be threaded. The capacity of cohesin for such topological entrapment of DNA is crucial for the phenomenon of post-replicative association of sister chromatids better known as cohesion. Recently, it became apparent that cohesin and other SMC complexes are in fact motor proteins with a very peculiar movement pattern leading to the formation of DNA loops. This specific process was called loop extrusion. Extrusion underlies multiple cohesin’s functions beyond cohesion, but the molecular mechanism of the process remains a mystery. In this review, we have summarized data on the molecular architecture of cohesin, the influence of ATP hydrolysis cycle on this architecture, and the known modes of cohesin–DNA interactions. Many of the seemingly disparate facts presented here will probably be incorporated in a unified mechanistic model of loop extrusion in a not so far future.
Towards development of the 4c-based method detecting interactions of plasmid dna with host genome
Authors: Yan A. P. , Salnikov P. A. , Gridina M. M. , Belokopytova P. S. , Fishman V. S.
Published: November 2024

Chromosome conformation capture techniques have revolutionized our understanding of chromatin architecture and dynamics at the genome-wide scale. In recent years, these methods have been applied to a diverse array of species, revealing fundamental principles of chromosomal organization. However, structural organization of the extrachromosomal entities, like viral genomes or plasmids, and their interactions with the host genome, remain relatively underexplored. In this work, we introduce an enhanced 4C-protocol tailored for probing plasmid DNA interactions. We design specific plasmid vector and optimize protocol to allow high detection rate of contacts between the plasmid and host DNA.
Urban protopops in the public life of Russia in the era of the political crisis of the early 17th century
Authors: Davidenko Dmitry G.
Published: November 2024

The article shows that the protopopes at the beginning of the XVII century usually took a patriotic position and opposed impostors and interventionists, which is especially clearly seen in Bryansk, Zaraysk, Nizhny Novgorod and Veliky Novgorod. Episodes of the protopops' loyal attitude towards the supporters of impostors are not typical and were caused by their presence in the occupied territories. The support of patriotic forces by the protopopes of Russian cities strengthened their position both within the clergy and in society as a whole, as manifested by their participation in the signing of the Approved Letter of Mikhail Fedorovich not among the Consecrated Cathedral, but as electors from places not traceable in an earlier era
In the vicious circle of bureaucratization and reform of parish life
Authors: Mangileva Anna V.
Published: November 2024

The paper discusses the main points and conclusions of A. L. Beglov's monograph "The Orthodox Parish at the Decline of the Russian Empire". It notes contribution of this research to the study of the history of the Russian Orthodox Church in general and the parish in particular.
Historian Ilya Evgenyevich Zelenin as shown through his scientific library
Authors: Chervyakov Ruslan Y.
Published: November 2024

The article analyses the scientific biography of Ilya Evgenyevich Zelenin – an outstanding agrarian historian, Doctor of Historical Sciences, Professor, leading researcher of the Institute of Russian History of the Russian Academy of Sciences. The main source used are copies of books presented to Zelenin, devoted to the agrarian and political history of Russia in the twentieth century. On their basis, a conclusion is made about the key elements of the historian's research credo, namely: painstakingness in working out the historiography of the issue, a wide archival search, accuracy of scientific terminology and understanding of the formality of ideological stamps. There are two stages in the author's scientific work, connected with the study of the history of state farm construction in the USSR and the history of agrarian policy of I. V. Stalin and N. S. Khrushchev, in each of which the historian achieved serious successes.
A man of iron will
Authors: Gusman Leonid Y.
Published: November 2024

The article analyzes the monograph by I. E. Barykina, dedicated to the life and work of D. A. Tolstoy.
Count D. A. Tolstoy – researcher of Catholicism
Authors: Samylovskaya Ekaterina A.
Published: November 2024

The review of the monograph by Inna Evgenievna Barykina, Doctor of Historical Sciences, under the title "A Typical St. Petersburg Officialو Count Dmitry Andreevich Tolstoy (1823-1889): the Experience of the Minister Biography" focuses on the characterization of D.A. Tolstoy as a researcher of Catholicism in Russia. It is noted that the monograph author is by no means inclined to exaggerate Count Tolstoy's contribution to the Catholicism historiography, however, his work served a valuable help to both the count's contemporaries and the 21st century scientists. I.E. Barykina convincingly showed that in all his positions, count D.A. Tolstoy proved himself not only as a statesman, but also as an intellectual and a historian who laid the foundations for studying the Catholicism history in Russia.
«The man of the system»
Authors: Rostovtsev Evgeniy A.
Published: November 2024

The article reviews the monograph by I.E. Barykina ("A typical St. Petersburg official" Count Dmitry Andreevich Tolstoy (1823-1889): The experience of the biography of the minister. M.; St. Petersburg, 2022). Noting the merits of the book by I.E. Barykina, the author of the review dwells on the problematic aspects of D.A. Tolstoy's biography. In particular, his role as an official in charge of the Academy of Sciences and Russian universities is considered, as well as a rare combination of the roles of a dignitary and a scientist in the bureaucratic environment of the hero of the reviewed essay.
Portrait of the mysterious triumvir
Authors: Kotov Aleksandr E.
Published: November 2024

Count D.A. Tolstoy is traditionally perceived, along with M.N. Katkov and K.P. Pobedonostsev, as one of the "triumvirs" who directed the policy of "counter-reforms". But if the fates and views of the other triumvirs have already been described in quite a variety of ways, then Count Tolstoy was less fortunate. Therefore, the monograph by I.E. Barykina is in a certain sense not only new, but also unique. Of course, it is written in the traditions of the same liberal and Soviet historiography and partially retains their cliches and assessments, but still its restrained style is far from both excessive complimentarity and caricature.
An enlightened reactionary
Authors: Mamonov Andrey V.
Published: November 2024

The article is devoted to the characteristics of the life, views, state and scientific activities of Count D.A. Tolstoy and their coverage in the latest monograph by I.E.Barykina.
Eparchial structure in Central Russia and the beginning of Peter the Great’s Reforms
Authors: Bashnin Nikita V. , Cherkasova Marina S.
Published: November 2024

The article analyzes the latest historiography devoted to the initial stage of Peter I's church reform. The authors showed that I. N. Shamina's monograph is a well-founded study on the Kolomna diocese, based on the analysis of a set of documents from F. 237 (Monastic Office) in the RGADA. The issue of completing the description of episcopal houses and monasteries is debatable. Thus, the inventory of the Solovetsky monastery was revealed, which dates back to 1705, and not 1701–1703. In general, the monograph of I. N. Shamina contains a valuable analysis of the identified sources and tells about the changes that took place in the life of the dioceses at the beginning of the 18th century.
ВПЛИВ ТРАНСФОРМАЦІЙНИХ ЗМІН НА ЕФЕКТИВНІСТЬ ФУНКЦІОНУВАННЯ ІННОВАЦІЙНИХ ПАРКІВ
Authors: КРИСОВАТИЙ Ігор
Published: November 2024

Innovation parks are key elements of modern innovation infrastructure aimed at the development of science, technology and support of entrepreneurship. In the conditions of rapid transformational changes caused by the development of digital technologies, globalization processes, growing requirements for environmental sustainability and social responsibility, innovative parks are faced with the need to adapt their business models and management approaches to maintain competitiveness and increase efficiency. The purpose of the presented work is to determine the features of the impact of transformational changes on the efficiency of the functioning of innovation parks. Methods used in the work: logical method, method of comparison, methods of analysis and synthesis, methods of deduction and induction, tabular and graphic methods for visual presentation of research results. It is also substantiated that the impact of transformational changes is manifested in the need for the integration of the latest technologies, digital solutions, as well as the application of innovative formats of cooperation, which leads to the rapid renewal of park infrastructure, the development of new services and approaches to knowledge management. Changes in the labor market, increased requirements for the qualifications of employees, and the intensification of work on projects focused on environmental sustainability make innovation parks centers of socio-economic progress and adaptation to the requirements of sustainable development. The impact of transformational changes is manifested in the need to integrate the latest technologies, digital solutions, as well as the use of innovative formats of cooperation, which leads to the rapid renewal of park infrastructure, the development of new services and approaches to knowledge management. Changes in the labor market, increased requirements for the qualifications of employees, and the intensification of work on projects focused on environmental sustainability make innovation parks centers of socio-economic progress and adaptation to the requirements of sustainable development. Thus, analyzing the impact of transformational changes on innovation parks is an important task for determining their role in the modern economy and finding effective solutions to preserve their relevance and effectiveness in the face of constant changes.
On the boundedness of the resolvent of the operator generated by partial operator-differential expressions of higher order in Hilbert space
Authors:   Institute of Mathematics and Mechanics, Baku, Azerbaijan, H.I. Aslanov
Published: November 2024

In the paper we consider the boundedness of the resolvent of a differential operator generated by partial operator-differential expression of higher even order in Hilbert space. The main theorem on the boundedness of the operator (L − λE)
Uma adolescente com espondilartrite e doença de Crohn
Authors:   USF Tiago de Almeida, Marto Liliana , Baptista Tiago ,   USF Tiago de Almeida, Sousa Renata ,   USF Tiago de Almeida, Martins Carla ,   USF Tiago de Almeida, Araújo Sara ,   USF Tiago de Almeida, Cruz Ana Lúcia ,   USF Tiago de Almeida, Pinhão Ana Raquel ,   USF Tiago de Almeida, Morais Catarina ,   USF Tiago de Almeida
Published: November 2024

Introdução: Este caso clínico descreve a jornada de uma adolescente que manifesta um quadro marcado por sintomas articulares e intestinais, permitindo evidenciar a relação entre espondilartrite e doença de Crohn. Descrição do caso: Adolescente de 15 anos recorre à consulta com a sua médica de família por dor articular, nomeadamente gonalgia bilateral e lombossacralgia, tendo a marcha diagnóstica indiciado uma possível doença autoimune, suportada por marcadores inflamatórios alterados e critérios de sacro-ileíte em ressonância magnética nuclear. Posteriormente surgiu um quadro de diarreia e hemorragia retal, tendo a colonoscopia revelado pancolite e ulcerações. Principais diagnósticos, terapêutica e resultados: a avaliação inicial por reumatologia sugeriu os diagnósticos diferenciais de espondilartrite e artrite idiopática juvenil. Neste contexto foram introduzidos analgésicos anti-inflamatórios não esteroides e prednisolona. Solicitou-se a colaboração de gastrenterologia pediátrica que, após articulação conjunta com reumatologia e a medicina geral e familiar, enquadrou os sintomas gastrointestinais num diagnóstico provável de espondilartrite associada a doença de Crohn, optando-se pela terapêutica com adalimumab. Comentário: Este caso destaca a importância da colaboração interdisciplinar na gestão de diagnósticos complexos e estabelecimento de estratégias terapêuticas adequadas em patologias autoimunes concomitantes. No âmbito da medicina geral e familiar, este caso reforça o papel do médico de família como gestor do doente e como elemento fulcral na aceitação da doença crónica pelo utente e sua família.
Aborto espontâneo e luto gestacional – Valorizar e gerir: um relato de caso
Authors:   ULS Lisboa Ocidental, Soares Renata Barbosa , Melo Ana Teresa ,   ULS Lisboa Ocidental, Cavaco Joana Pimentel ,   ULS Lisboa Ocidental, Faria Marina ,   ULS Lisboa Ocidental
Published: November 2024

Carta ao editor referente ao artigo Aborto espontâneo e luto gestacional – Valorizar e gerir: um relato de caso, publicado em julho de 2024, na RPMGF. Foi feita análise dos aborto espontâneos, de janeiro de 2023 a junho de 2024, na nossa USF, de modo a fazer um paralelismo com a gestão do relato de caso publicado. Após reflexão, consideramos fundamental a abordagem do impacto na saúde mental de um luto gestacional e um acompanhamento à posterior pelo médico de família.
A Difficult Road: Update on the Educational-Vocational Impact of Disability in Australia
Authors: Athanasou James
Published: November 2024

This is the sixth in a series of reports from 1999 that describe the impact of disability in Australia on earning and learning. The purpose is to summarise the official statistics on _Disability Ageing and Carers_ by the Australian Bureau of Statistics. Whilst almost three-quarters of those aged 15-64 years without a reported disability completed Year 12 only just over a half of those with a disability completed the highest level of secondary schooling. In the labour market, the participation rate has always been lower for persons with a disability compared to those without a disability. It was concluded that even when people with disabilities are ready to work the rate of unemployment is more than double for those without a disability.
Lyme disease in Poland in 2022
Authors: Zbrzeżniak Jakub Maciej , Paradowska-Stankiewicz Iwona
Published: November 2024

Introduction

In Poland, Lyme disease has been subject to mandatory reporting and registration since 1996, and following EU law, cases of neuroborreliosis have been reported to the European Centre for Disease Prevention and Control (ECDC) since 2019. Lyme disease is transmitted by ticks of the Ixodes genus, and humans become infected through the bite of an infected tick. Due to the varied symptoms, diagnosis can be difficult and usually involves two-stage serological diagnostics. The aim of the study was to assess the epidemiological situation of Lyme disease in Poland in 2022 compared to the situation in previous years.

Material and Methods

The epidemiological situation of Lyme disease in Poland was assessed on the basis of the data sent to NIPH NIH – NRI by voivodeship sanitary-epidemiological stations and published in the bulletin “Infectious diseases and poisoning in Poland in 2022”.

Results

In 2022, 17 369 cases of Lyme disease were registered, including 776 hospitalizations. This was a significant increase in cases by 38.96% and hospitalizations by 88.81% compared to the previous year. The seasonality that characterizes Lyme disease was noticeable in individual quarters, i.e. an increase in the number of cases from 1 151 in Q1 to 7 267 in Q3 and a decrease in Q4 to 5 708. At the voivodeship level, the highest incidence was recorded in the Podlaskie (81.2 per 100 000), Małopolskie (79.8 per 100 000) and Lubelskie (76.8 per 100 000) voivodeships.

Conclusions

The epidemiological situation of Lyme disease is gradually returning to the state before the COVID-19 pandemic. The percentage of hospitalized cases increased slightly (from 3.3% in 2021 to 4.5% in 2022), which, combined with the increase in the number of cases, meant an increase in the number of hospitalizations due to Lyme disease by almost 89%. The highest incidence was consistently observed in the eastern part of Poland (Podlaskie, Warmińsko-mazurskie, Lubelskie voivodeships).
Evaluating generative AI tools: A comparative guide for new users
Authors: Iglesias Rojas Oscar Ivan , Quintero Monroy Christian Giovanny
Published: November 2024

One of the most prominent forms of artificial intelligence that has been made public is generative AI, which offers a fresh perspective and direction for numerous global sectors. The impact of this artificial intelligence model on nearly every business and how certain vocations can be pursued has garnered a large audience. This paper evaluates generative AI from an objective standpoint and proposes a comparison of some of its key tools to help new users solve problems in their daily lives, at work or at home. This highlights the significance of understanding and utilizing this kind of AI.
Música, representación y conflicto en América Latina
Authors: Marín-López Javier , Ramos-Kittrell Jesús
Published: November 2024

América Latina cuenta con una historia densamente conflictiva en sus procesos de representación cultural, como consecuencia de las sucesivas colonizaciones, los movimientos independentistas del siglo XIX, la articulación de identidades nacionales en relación con teorías de dependencia económica y los impactos sociales de la globalización y el neoliberalismo en las estructuras estatales. Este conjunto de ensayos explora el papel de la música como un medio de resistencia, expresión y reflexión en contextos conflictivos en diferentes momentos de la historia latinoamericana.