bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Obesity and Cardiovascular Risk in Postmenopausal Women
Authors: ERTEN BUCAKTEPE Pakize Gamze , ÇELEPKOLU Tahsin , ASLAN İlknur , TANRIVERDİ M.halis , YILMAZ Ahmet , ASLANHAN Hamza , KARS Veysel
Published: July 2019

Objective: The
aim of this study was to investigate the relationship between obesity and
cardiovascular risk in postmenopausal women.

            Methods: The study included 43 postmenopausal women who were
admitted to Dicle University Medical School Family Medicine Outpatient Clinic in
2011. Body mass index (BMI), waist and hip circumferences, body fat mass and
percentage, 24-hour arterial tension measurements, homocysteine (Hcy) level,
vitamin B12 level, and Framingham risk score (FRS) were compared between obese
(BMI>30 kg/m²) and non-obese (BMI≤30 kg/m²) patients.

            Results: The patients included 24 (55.8%) obese and 19 (44.2%)
non-obese patients. Abdominal obesity was seen in 29 (67.4%) and truncal
obesity in 33 (76.7%) participants. Family history of cardiac disease was seen
in 25 (58.1%) women, most of whom were obese. Based on FRS, moderate
cardiovascular risk was assessed in 21.6%, but none of the participants were at
high risk. FRS was higher in patients with Hcy levels of ≥15 µmol/L. In
addition, the Hcy values increased with age and there was a negative
correlation between Hcy levels and vitamin B12 status (r=-0.322, p=0.035).

            Conclusion: The results of this study indicate that age- and gender-dependent
differences must be taken into consideration for cardiovascular risk
assessments and postmenopausal women should be informed about obesity and
hypertension in order to improve their quality of life.Özet            Amaç:
Bu çalışmada postmenopozal kadınlarda obesite ve kardiyovasküler risk
ilişkisinin incelenmesi amaçlanmıştır.            Gereç-Yöntem: çalışmaya Dicle Üniversitesi Tıp Fakültesi Aile
Hekimliği Polikliniğine 2011 yılında başvuran 43 postmenopozal kadın dahil
edilmiştir. Beden kitle indeksi (BKİ), bel ve kalça çevresi, vücut yağ kitle ve
yüzdesi, 24-saatlik kan basıncı ölçümleri, homosistein (Hcy) düzeyi, vitamin
B12 düzeyi ve Framingham risk skorlaması (FRS)  obez olan (BKİ>30 kg/m²) ve obez olmayan (BKİ≤30
kg/m²) kadınlarda ölçülerek karşılaştırılmıştır.Bulgular: Kadınların
24’ü (%55.8) obez ve 19’u (%44.2) non-obezdi. Abdominal obezite 29 (%67.4),
trunkal obezite 33 (%76.7) hastada mevcuttu. Kardiyak hastalık aile öyküsü,
çoğu obez olan 25 (%58.1) kadında tespit edildi. FRS’ye göre orta düzeyde  kardiyovasküler risk %21.6 oranında
saptanırken hiçbir kadın yüksek risk grubunda değildi. FRS, Hcy seviyesi ≥15
µmol/L olan kadınlarda daha yüksekti. Hcy seviyesi yaşla artmaktaydı ve Hcy ile
vitamin B12 arasında negative korelasyon mevcuttu (r=-0.322, p=0.035).Sonuç: Bu
çalışma kardiyovasküler risk değerlendirmesine yaş ve cinsiyete bağlı
farklılıkların göz önünde bulundurulması ve postmenopozal kadınların, yaşam
kalitelerini arttırmak için obezite ve hipertansiyon konusunda
bilgilendirilmeleri gerektiğini göstermektedir.

Anahtar Kelimeler: Obezite,
Homosistein, Vitamin B12, Kan
basıncı Monitorizasyonu, Framingham Risk Skorlaması.
Analysis of Bone Mineral Density and Hip Fracture in Geriatric Patients with Heart Failure
Authors: ARSLAN Arslan Kağan , TOLUNAY Hatice
Published: July 2019

Objectives: Osteoporosis
defined by low Bone Mineral Density (BMD), is a progressive disease affecting
especially older adults. Hip fracture is the important result of osteoporosis.  For the older adults, heart failure (HF) and
osteoporosis are two common chronic conditions that are gaining importance for
healthcare. The aim of this study is to evaluate bone mineral density and hip
fractures in geriatric aged patients with heart failure

Methods: We retrospectively analyzed 157 geriatric
patients with heart failure and 155 geriatric control subjects without any
cardiovascular disease and risk factors. All subjects underwent transthoracic
echocardiography, biochemical analysis, and bone DEXA study. Osteoporotic
fracture history and operation for fracture, list of current and prior use of
medications were obtained from each center’s medical recordings.

Results: Among the 157 patients, 45 (29%) had normal
BMD, 14 (9%) had osteopenia, and 98 (62%) had osteoporosis.  In 155 control subjects,68 (44%) had normal
BMD, 12 (8%) had osteopenia, and 75 (46%) had osteoporosis (P=0.019). Sixteen
subjects (10.2%) in heart failure group and 6 subjects (3.9%) in controls had
hip fracture (p=0.029). Level of 25-hydroxyvitamin D was significantly lower in
heart failure than in controls (15.1±10.2 vs. 29.1±20.4 ng/ml; p<0.001).

Conclusion: Patients with heart failure have a lower bone
mineral density, low vitamin D level and an increased rate of hip fractures.
These findings can be explained by shared risk factors and pathogenetic
mechanisms. Further prospective studies should be performed for evaluating the
role of heart failure in osteoporotic hip fractures.
Diş Hekimlerinin HIV/AIDS ve Oral Lezyonlar Hakkındaki Bilgi Düzeyi ve Tutumlarının Değerlendirilmesi
Authors: İNCE Nevin
Published: July 2019

Amaç: İnsan
İmmün Yetmezlik Virüsü (HIV), bağışıklık sistem hücrelerini hedef alarak
enfeksiyon oluşturan ve enfeksiyon ilerlediğinde Edinilmiş İmmün Yetmezlik
Sendromuna (AIDS) neden olabilen bir virüstür. Bu çalışmanın amacı, Diş
Hekimlerinin HIV/AIDS hastalığının olası bulaş yolları, HIV’nin bulunabileceği
vücut sıvıları ve HIV/AIDS’in ağız içi belirtileri ile ilgili bilgi düzeylerini
saptamak, bilgiye ulaşım yollarını belirlemek, hastalara karşı tutum ve farkındalıklarını
değerlendirmektir.Gereç ve Yöntem: SurveyMonkey
anket sistemi ile 17 soruluk anket hazırlandı. Hazırlanmış olan link, Diş
hekimlerine mail, cep telefonu ve sosyal paylaşım üzerinden gönderilerek
yanıtlanması istendi. Anketi yanıtlayan 180 hekimin cevapları değerlendirildi. Bulgular:
Anketi cevaplayan Diş hekimlerinin %73'ü
kadın, %43’ü 31-40 yaş aralığında idi. HIV/AIDS hastalarının ağız lezyonları
hakkında bilgileri sorulduğunda %39,6'sı oral candidiazis olarak yanıtladı. HIV/AIDS
bilgi düzeyini ölçen sorularda; %28,4'ü HIV ve AIDS’in aynı tanım olmadığını %99’u
korunmasız cinsel ilişki, kan teması ve kesici delici aletlerle yaralanma ile bulaş
olduğunu bilmekteydi. Önemli bir oranda diş hekimi; idrar ve  tükürük ile bardak, havlu gibi ortak
kullanılan malzemelerle de bulaştığını ifade etmişlerdi. HIV enfekte hasta ile
ilgili tutumları değerlendirildiğinde, katılımcıların yarısından fazlası
çekinmeden tedavi yaparım olarak yanıtlamıştı. Hastalardan kendilerine HIV
bulaşma endişesi olup olmadığı sorulduğunda, %40’ı evet yanıtını vermişlerdi. HIV/AIDS
hakkındaki bilgilerini en çok fakültede (%85) ve yazılı kaynaklardan (%56,1)
edindiğini ifade etmişlerdi. Diş hekimlerinin %73,3’ü HIV/AIDS ve oral
lezyonlar hakkında yeterli bilgiye sahip olmadıklarını ve bilgilerinin
güncellenmesini istediklerini belirtmişlerdi.

Sonuç: Çalışmamızda
diş hekimlerinin bilgi
düzeyinin genel olarak kabul edilebilir olmasına rağmen, HIV'in bulaş yolları
konusunda yanlış bilgi ve tutum olduğu görülmüştür.  Mezuniyet sonrası sahada çalışan diş
hekimlerine yönelik bilgilerin güncellenmesinin önemli olduğu düşünülmüştür.
Obowiązek władz publicznych prowadzenia polityki zapewniającej bezpieczeństwo ekologiczne rozumiane jako synonim odpowiedniej jakości środowiska
Authors: Jaworowicz-Rudolf Agnieszka
Published: July 2019

W artykule autorka analizuje kwestie konstytucyjnego zobowiązania władz publicznych do dbałości o jakość środowiska z uwzględnieniem troski o przyszłe pokolenia. Wskazuje, iż pojęcie bezpieczeństwa ekologicznego nie zostało przez prawodawcę sprecyzowane, a poglądy formułujące prawo do bezpieczeństwa ekologicznego uznawane są za sporne. Podkreśla, że aktualnie kluczowym wyzwaniem dla władz publicznych jest problem niskiej emisji.
Utilizing Exposure and Response Prevention to Address Poor Insight in Obsessive-Compulsive Disorder
Authors: Middleton Rachel R. , Hezel Dianne M.
Published: July 2019

Studies indicate that approximately 9%–30% of adults diagnosed with obsessive-compulsive disorder have poor insight into their symptoms. That is, they fail to recognize the excessiveness or irrationality of the obsessive thoughts or their compulsive behaviors. Poor insight in OCD is associated with more severe symptoms, earlier age of illness onset, longer illness duration, and higher rates of comorbid depression. Moreover, some studies have also reported that patients with poor insight are less likely than are those with good or fair insight to respond to first-line treatments such as exposure and response prevention (ERP). Despite the clinical relevance of poor insight, very little research has focused on how to enhance therapy with strategies specifically used to target it. In this report, we use a case study to demonstrate how different techniques can be emphasized or integrated with standard ERP to improve treatment outcomes for this subset of patients.
Effectiveness of different endodontic irrigants against Enterococcus faecalis: an ex vivo study.
Authors: Pedro Fabio Luis Miranda , Nunes Lenieser Fajardo , Pereira Thiago Machado , Pivatto Kellin , Estrela Cyntia Rodrigues de Araujo , Amezcua Octavio , Borges Alvaro Henrique Borges Henrique
Published: July 2019

Aim: To evaluate the effectiveness of different endodontic irrigants against Enterococcus faecalis (ATCC 29212).Methods: Seventy bovine mandibular incisors were prepared, inoculated with a bacterial strain for 60 days and divided into the following groups: positive control; negative control; 2.5% NaOCl; 17% EDTA; 0.2% chitosan; 2.5% NaOCl + 0.2% chitosan; and 2.5% NaOCl + 17% EDTA. The irrigation protocol was performed using an experimental peristaltic pump device, with the irrigating solutions circulating within the apparatus at a constant flow for 10 min. Paper-point samples were then collected from the root canals and immersed in 7 mL of brain heart infusion broth, followed by incubation at 37°C for 48 h. Bacterial growth was assessed by turbidity of the culture medium.Results: E. faecalis was present in all samples after the use of different irrigants.Conclusion: The different irrigants tested were not effective in completely eliminating dentin bacterial contamination with E. faecalis.
LA INCLUSIÓN LABORAL PARA EL TRABAJO DIGITAL
Authors: Camacho Solís Julio Ismael , Román Fuentes Juan Carlos
Published: July 2019

Los avances, la sistematización de la vida cotidiana; así como las comunicaciones innovadoras intercalados con los sistemas de información de hoy día son determinados por el desarrollo tecnológico mundial, así como por plataformas digitales, estos esquemas han inﬂuido diversos ámbitos de la sociedad en general y de manera particular en las relaciones de trabajo sean estas sean estas informales o formales que han generado nuevas formas de relacionarse con una determinada característica que impacta en la organización y en el desarrollo del trabajo que da como resultado que las empresas y organizaciones diseñen diversas modalidades, basada en sus propias necesidades empresariales para contratar trabajadores con alguna característica en particular, donde por lo consiguiente quedan fuera de los ordenamientos jurídicos típicos y tradicionales que protegen los derechos de los trabajadores, que dan certeza jurídica a la relación laboral.
AS LIBERDADES CIVIS E A INTERNET
Authors: Sousa Ana Claudia
Published: July 2019

O Marco Civil da Internet foi aprovado em 2014, onde veio a estabelecer regras de direitos e deveres aos usuários da rede, passando a ter como fundamentos legais o respeito à liberdade de expressão, aos direitos humanos, dentre outros princípios. Podemos afrmar então, que o Marco Civil é uma espécie de “Constituição da Internet”, visando à regulamentação, através de uma “carta de princípios”, dos direitos e deveres dos usuários da internet, dos portais e sites, das prestadoras de serviço, como também do Estado. Esta regulamentação trata-se, portanto, de uma institucionalização burocrática sobre o que é certo e o que é errado no mundo virtual, e, os pontos que foram discutidos nesse projeto gerou inúmeros debates durante a sua tramitação, pois se referiram à liberdade, à privacidade e à neutralidade da rede. De certo, que, os dados pessoais, como às liberdades, devem ser protegidos para garantir o respeito pela dignidade e privacidade individuais, e, serem tratados de acordo com os princípios da necessidade, fnalidade, relevância e proporcionalidade, e, só podem ser coletados e processados com o consentimento da pessoa em questão. A Internet não deveria estar sujeita a um maior controle regulatório do que os meios de comunicação tradicionais, será?
Pregled metod za določanje številčnosti prostoživečih parkljarjev
Authors: Flajšman Katarina , Fležar Urša , Pokorny Boštjan , Jerina Klemen
Published: July 2019

The information on absolute and/or relative abundance of wild ungulates is one of the key parameters for sustainable and efficient management. Wild ungulates are the most important and abundant group of game species in Slovenia; however, there are currently no standard census methods, which would be performed on the annual basis. There are various methods for estimating wild ungulate abundance and several criteria have to be met, when selecting the most suitable one. The most important criteria that have to be taken into account are studied species, habitat characteristics, size of the studied area, population density and cost efficiency. Besides the faecal pellet group method, which has already been used in Slovenia to estimate the abundance of roe deer and red deer, a suitable method is also the kilometre index. The reliable methods for wild boar are camera traps, drive counts and distance sampling with thermovision and, for chamois, ground counts and aerial counts.
Reliefne značilnosti tal in objedanje mladja s strani velikih rastlinojedih parkljarjev v jelovo-bukovem gozdu
Authors: Roženbergar Dušan , Klevišar Robert , Diaci Jurij
Published: July 2019

Ungulates affect the development of forest ecosystems in different ways. The most negative impact is a result of a long-term intense overbrowsing of regeneration. The aim of this study was to determine the effect of habitat characteristics and topography on browsing damage to regeneration in Dinaric beech-fir forests. The average damage rate across all tree species of regeneration was 70 %, and the analysis of the regeneration height structure showed that there was no recruitment of sycamore maple and silver fir into the upper height layers. We confirmed the influence of cover level for ungulates and topographical position on the browsing damage rate. Most of the damages were recorded on ridges and in sinkholes. According to the results of our study, it will not be possible to provide, at current browsing rates, admixtures of silver fir and sycamore maple in the upper canopy. In order to achieve diverse structure and species composition in these forests, in addition to silvicultural measures, it will be necessary to continue active management of ungulate populations focused on reducing densities.
Pobreza y desigualdad en México. La construcción ideológica y fáctica de ciudadanías diversas y desiguales
Authors: Damián Araceli
Published: July 2019

Con base en una reflexión sobre el concepto de ciudadanía social desarrollado por T. H. Marshall, se propone que los derechos económicos, sociales y culturales (DESC) están asociados con necesidades cuya satisfacción depende de recursos económicos y, por lo tanto, involucran la pobreza. Se plantea que el derecho a no ser pobre quedaría en un nivel muy abstracto si no se especifica lo que se requiere para no serlo. Partiendo de esta idea se analizan los derechos reconocidos en la Constitución y en los tratados internacionales. Se destaca la relevancia de la definición de los umbrales de satisfacción para vivir sin pobreza. Se revisa críticamente el método oficial para medir la pobreza multidimensional (Coneval) y se concluye que, al fijar en el método oficial normas de satisfacción bajas en todas las dimensiones (como el Seguro Popular en salud), la medición oficial es violatoria de los desc. Se presenta la evolución de la pobreza en México para el periodo de 1968 a 2016, con distintos métodos. Se describen los retrocesos experimentados, particularmente a raíz de las crisis y del cambio de modelo económico en los últimos 30 años. Con base en el método de medición integrada de la pobreza (MMIP) se incluye un análisis de las diferencias territoriales de la pobreza, de la desigualdad en el ingreso a nivel nacional y en el acceso a los servicios de salud y seguridad social por deciles.
PENGARUH EKSPOR IMPOR TERHADAP TRANSAKSI BERJALAN INDONESIA SEBELUM DAN SESUDAH SUBPRIME MORTGAGE
Authors: Bagaskoro Mayong Noor
Published: July 2019

This study is to determine the effect of exports and  imports on the current account of Indonesia and comparison before and after the 2008’s subprime mortgage crisis. The analytical method used is mutiple regression and strcutural break test. The regression results show that exports have positive effect and imports have negative effect on current account of Indonesia. While the structural break test show that there are differences in the comparison effect of export and import on the current account of Indonesia in the before and after the crisis.
Confronting Urban Electricity Demand with Wind Energy Supply: Case Study in Ecuador
Authors: Ayala Manuel , Riba Genís
Published: July 2019

On 2013 the Villonaco wind farm (16.5 MW), the first wind farm in continental Ecuador near the city of Loja, began operations. The power generated is delivered to the National Interconnected System (SNI), which services the city. This research confronts two sets of real data, the electricity use of the urban area of Loja, and the power generated by the Villonaco Wind Farm. Electricity use follows clearly defined daily and weekly cycles, and wind power has a seasonal behaviour. The study shows that wind power integration cannot be a long-term stable power source regardless power or generation surplus. Another essential finding is that time series can be used as a statistical source to determine the need for short- (seconds) and long- (days, weeks) term energy storage. Strategies to further the energy autonomy of the urban area through the expansion of the wind farm by a factor of 2 are discussed.
Amendements on Salinity and Water Retention of Sand Base Rootzone and Turfgrass Yield
Authors: Rahayu Rahayu , Mo Yang Geun , Soo Choi Joon
Published: July 2019

This research was column pot experiment with turfgrass was Kentucky bluegrass (Poa pratensis) plant irrigated saline irrigation and the column soaked in saline water. Rootzone profile consisted of 20 cm using saline lake dredged up sand. The sand amendments of the root zone were soil, zeolite, bottom ash, and peat. The mixtures of topsoil were; 90% sand + 10% peat moss, 80% sand + 10% soil + 10 % bottom ash, 80% sand + 20% soil, 90% sand + 5% peat + 5% zeolite, and 80% sand + 20% bottom ash. Interruption layer with coarse sand with diameters over 2 mm of 20 cm and 10 cm loamy soil as the bottom layer of the column. The result showed that Kentucky bluegrass could grow in sand based growing media amended by peat, sandy loam soils, bottom ash and zeolite being irrigated by 2 dS m-1 saline water. Sand-based growing media amended by peat resulted in the highest clipping weigh but showed the highest salt accumulations. Sand amended by bottom ash and applied gypsum decreased clipping weigh, decreased SAR and increased calcium (Ca) when compared to the soil + peat (SP).  Sand amended by zeolite and gypsum decreased clipping weight, decreased sodium adsorption ratio (SAR) and higher Ca. Higher soil moisture retention of growing media promoted the growth of Kentucky bluegrass in spring, and lower moisture content promoted the growth in summer and fall season.
Risk-Oriented Characteristics of the Current Epidemiological Situation on West Nile Fever in the Astrakhan Region
Authors: Kovalevskaya A. A. , Vasil’kova O. L. , Agapov B. L. , Kouklev E. V. , Safronov V. A. , Shcherbakova S. A. , Nikeshina N. N. , Noskova L. N. , Arshba T. E. , Rudenko G. G. , Shishlonov A. M.
Published: July 2019

Objective – risk-oriented assessment of the current epidemiological situation on West Nile fever in the Astrakhan Region.

Materials and methods. Utilized were the data collected by the Astrakhan Plague Control Station, Rospotrebnadzor Administration in the Astrakhan Region, and A.M. Nichoga Regional Infectious Clinical Hospital. The key method of study was epidemiological analysis of West Nile fever incidence among the population of the Region during the period of 2000–2016. 145 case records were investigated.

Results and discussion. Retrospective analysis provided for identification and featuring of the main categories of epidemiological risk of infection with West Nile fever in the Astrakhan Region in 2000–2016. It was established that men of 19 to 70 age range ( 82.1 %) are infected more often (95 out of 145 – 65 %). WNF infections in women occur among the same age group (75.8 %), and also among children aged below 6 years old (9.0 %). Analysis of the risk territories showed that the level of risk is high in one district, medium – in one district, low – in four districts, and very low – in six. When investigating the conditions of infection (risk factors) with WNF, it was determined that in the majority of cases (107 – 73.8 %) the risk factors were not specified. Out of those that were identified, one should pinpoint the bite of mosquito inside the households, basements, while fishing (16.3 %), as well as the bite, removal or squashing of a tick with unprotected hands (6.9 %). The period of the highest risk is from May to October with the maximum values of incidence in August (55.1 %).
Detection of Crimean-Congo Hemorrhagic Fever Virus Markers in Samples of Ixodes Ticks Collected in the Territory of the Republic of Guinea
Authors: Naydenova E. V. , Zakharov K. S. , Kartashov M. Yu. , Agafonov D. A. , Boiko A. V. , Kas’yan Zh. A. , Senichkina A. M. , Nikiforov K. A. , Oglodin E. G. , Shipovalov A. V. , Dubinina A. A. , Porshakov A. M. , Nourdine I. , Diallo M. G. , Nassour A. A. , Kourouma A. , Drame F. , Safronov V. A. , Lopatin A. A. , Boumbali S. , Kalivogui S. , Boiro M. Y. , Shcherbakova S. A. , Kutyrev V. V.
Published: July 2019

Objectiveof the study. This work was carried out to identify markers (antigen and RNA) of CrimeanCongo hemorrhagic fever (CCHF) virus in samples from ticks, collected in all landscape-geographical areas of Guinea: Lower, Middle, Upper and Forest, to obtain up-to-date data on the distribution of the pathogen in the country.

Materials and methods. Total of 4276 specimens of 8 species of ticks collected in 2016–2019 in the territory of the Republic of Guinea were studied, which were compiled into 1406 samples. Ectoparasites were collected from livestock animals, dogs, and small mammals. Viral antigen was detected using enzyme immunoassay (ELISA). The presence of RNA of the CCHF virus was determined by reverse transcription polymerase chain reaction (RT-PCR).

Results and discussion. As a result of the studies, the antigen of the CCHF virus was detected in 21 samples (1.5 %), and RNA – in 37 (2.6 %). All samples, in which the viral antigen was detected, contained RNA of the CCHF virus. Positive results were obtained in samples from all geographical areas of the country. The main vectors and reservoirs of the pathogen in Guinea are ticks of the species Rh. sanguineus, Rh. geigyi, Rh. annulatus and Am. variegatum. The data obtained confirm the previously available information on the possibility of the pathogen circulation in this region and determine the need for further study of the spread of the CCHF virus in the territory of the Republic of Guinea.
Kontruksi Etika Maduraisme Dalam Kode Etik Akuntan Profesional: Internalisasi Nilai “Gaik Bintang” Dalam Etika Profesi Akuntan
Authors: Djasuli Mohamad
Published: July 2019

This article has objectives to concots values of madurese culture’s local wisdoms in order to build the concept of accounting profession’s code of ethics in Indonesia holitically. The main foundation of the holistic accounting profession’s code of ethics in Indonesia is the local wisdoms in which are taken from the madurese culture from the madura folk song entitled “Ghai’ Bintang”. Ghai’ Bintang lyrics are full with God’s value that is implemented in honesty value and this is one of the charasterics of madura people in their daily life. The holistic concept will be very important in this research as the foundation that will be internally fused in the building of the holisctic Indonesian Accountant Code of Ethics  with the Ghai’ Bintang song. The Holistic approach is a way in a research in building new concept from the previous one. This research has produced  the holisctic Indonesian Accountant Code of Ethics in which based on the values of knowledge principles, competence, defenselesness, grateful, and happiness. Those five principles must be covered with hinesty value as the spearhead of moral that has to be owned by each accountant. Those principles are part of the transformation of God Values that must be applied by every human being in the earth. Thus, this is also a responsibility for each accountant when they take action in their professional activities. Moreover, the implementation of Madura local culture ethical value may become a new foundation of the reformation of accounting profession’s code of ethics in Indonesia in this industry revolution era.
Analisis Faktor Yang Mempengaruhi Perilaku Nasabah Perbankan Konvensional Beralih Ke Perbankan Syariah (Studi Empiris Pada Mahasiswa Perguruan Tinggi di D.I.Y)
Authors: Saud Ilham Maulana , Teguh Iman , Nugraheni Peni
Published: July 2019

This study aims to analyze and prove empirically the influence of knowledge, religiosity, accessibility, and extra curricular islamic program to conventional banking customer behavior that switch to sharia banking. The subjects of this study are students of accounting study programs that become conventional banking customers and switch to sharia banking, whether really switching or not really switching. The object of this study is the institutions of college in the Special Region of Yogyakarta. In this study the sample of 82 respondents selected using purposive sampling method. The analysis used in this research is multiple linear regression analysis using SPSS 24.0. Based on the analysis that has been done obtained the result that the knowledge and extra curricularislamic program does not affect the behavior of conventional banking customers to switch to sharia banking. While religiosity and accessibility proved to have a positive and significant effect.
Pengaruh Tekanan Ketaatan, Pengetahuan, Dan Pengalaman Auditor Terhadap Audit Judgment
Authors: Tampubolon Lambok
Published: July 2019

This research is quantitative research. The data used in this study is primary data by distributing questionnaires to public accounting firms domiciled in DKI Jakarta. The population in this study were auditors who worked in the Public Accounting Office. Questionnaires were distributed as many as 130 questionnaires and data that could be processed as many as 100 questionnaires. Data is processed using the help of SPSS 23. The purpose of this study is to examine the effect of auditor compliance, knowledge and experience on audit judgment. From a sample of 17 public accounting firms in DKI Jakarta, this study shows that: (1) obedience pressure has a significant positive effect on audit judgment, (2) knowledge has a significant positive effect on judgment audits, and (3) auditor experience has no effect on judgment audit.
MENUJU SISTEM PENGENDALIAN MANAJEMEN BERTANGGUNG JAWAB SOSIAL STUDI PADA PT. PELINDO MARINE SERVICE SURABAYA
Authors: Kompyurini Nurul
Published: July 2019

This study has two objectives. First, to find out how corporate social responsibility (CSR) is defined, and second, to find out whether CSR has been integrated in the management control system (MCS). The theoretical foundation is built from various research articles and literature on corporate social responsibility and management control systems. The object of this research was PT. Pelindo Marine Service Surabaya (PT. PMS). The data in this study comes from interviews with company management.

The findings in this study are that the company cannot determine the objectives of social responsibility related to its stakeholders. This contributes to the absence of integration of social responsibility into the MCS. The lack of social responsibility goals related to stakeholder groups has caused the integration of these aspects into MCS to be hampered, and this has the potential to reflect the organization's seriousness in following its stakeholder approach.
PERBANDINGAN KINERJA PEMERINTAH DAERAH DI INDONESIA
Authors: Nurhayati Netty , Rizani Fahmi , - Kadir
Published: July 2019

This study aims to compare the performance of  district / city governments  in Indonesia that obtain WTP and Non-WTP opinion from BPK RI for 2014-2016 period. The financial performance variables are measured by financial ratios (decentralization degree ratio, independence ratio, effectiveness ratio , growth ratio) and performance of local government administration are measured by performance evaluation score of local government administration (EKPPD score). Sampling method using purposive sampling with judgment sampling technique. The sample in this study 216 districts / cities, consisting of 108 districts / cities that obtain WTP opinion and 108 districts / cities that obtain Non-WTP opinion. Hypothesis testing using nonparametric test ‘Mann-Whitney U Test’. The results of this study, state that the financial performance of local government and performance of local government administration on district / city governments in Indonesia that obtain WTP opinion is significantly different and better than district / city governments in Indonesia that obtained Non-WTP opinion. This difference shows that district / city  government that obtain WTP opinion has proven to be better in terms of financial management and local government administration compared to those who obtain Non WTP opinions.
An Integrated Approach To Optimize Bottomhole-Pressure-Drawdown Management for a Hydraulically Fractured Well Using a Transient Inflow Performance Relationship
Authors: Wang Junlei , Luo Wanjing , Chen Zhiming
Published: July 2019

The purpose of this paper is to determine the optimal strategy of bottomhole-pressure (BHP) drawdown management in a hydraulically fractured well with pressure-sensitive conductivity to remain conductive while maintaining a high enough drawdown to maximize the estimated ultimate recovery (EUR). In this work, a novel permeability-decay coefficient accounting for dynamic conductivity effect (DCE) is proposed to represent the pressure sensitivity in a fracture on the basis of experimental results. Using an existing method, the constant/variable BHP conditions and the hydraulic fractures with DCE are considered in the model. Model verification is performed by comparing with the solutions from the numerical method. Then, the mechanism of fracture closure and its effect on production performance are investigated using the semianalytical solution, and the interplay between pressure drawdown and productivity loss is captured by generating a set of type curves for the transient inflow performance relationship (TIPR).

Next, an easy-to-use approach is developed to find the optimal path of BHP decline vs. time, and the practical optimal drawdown is calibrated by capturing the time-lapse behavior, with consideration of the effect of production history on TIPR. It is found that if the relation of decay coefficient and pressure is a linear function, there will be a reversal behavior on TIPR as BHP drawdown increases. That is to say, an operating point exists on the TIPR curves, beyond which the production rate decreases; otherwise, the production rate increases. The operating point is defined as the optimal BHP drawdown at a given time, and the optimal profile of BHP drawdown is achieved by integrating operating points on TIPR curves corresponding to different times. Subsequently, a synthetic case generated by a coupled-geomechanical/reservoir simulator is defined to demonstrate that an optimal BHP-drawdown schedule developed by the semianalytical approach has the ability to enhance ultimate recovery by reducing the effective stress on the stress-sensitive fracture while maintaining the well productivity.
Determinants of Birth Asphyxia among Newborns in Amhara National Regional State Referral Hospitals, Ethiopia
Authors: Meshesha Alemwork Desta , Azage Muluken , Worku Endalkachew , Bogale Getahun Gebre
Published: July 2019

Background

Globally, every year, 2.5 million infants die within their first month of life. Neonatal asphyxia is the leading specific cause of neonatal mortality in low- and middle-income countries, including Ethiopia. Therefore, the aim of this study was to identify the determinants of birth asphyxia among newborns admitted in Amhara region referral hospitals, Ethiopia.

Methods

Facility-based unmatched case-control study was employed among 193 cases and 193 controls of newborns. Newborns admitted to neonatal intensive care units with admission criteria of birth asphyxia and without birth asphyxia were considered as cases (Apgar score<7) and controls (Apgar score>=7) respectively. Data were collected using a structured questionnaire by systematic random sampling technique with proportional allocation, and entered in to Epi-Info version 7 and exported to SPSS version 20 for statistical analysis. Bivariate and multivariable logistic regression models were fitted to identify determinants of birth asphyxia.

Results

Newborns with low birth weight (<2.5kg) had 8.94 higher odds of birth asphyxia than those whose weight at birth was >=2.5kg at birth (AOR: 8.94, 95% CI: 4.08, 19.56). Newborns born at health centers were 7.36 times more likely to develop birth asphyxia than those born at hospitals (AOR: 7.36, 95% CI: 2.44, 22.13). Newborns born using instrumental delivery were 3.03 times more likely to develop birth asphyxia than those delivered by vaginally (AOR: 3.03, 95% CI: 1.41, 6.49). Newborns from mothers with prolonged labor were 2 times more likely to suffer from birth asphyxia as compared to their counterparts (AOR: 2.00, 95% CI: 1.20, 3.36).

Conclusion

This study identified prolonged labor, instrumental delivery, delivered at health centers, and low birth weight were identified as determinants of birth asphyxia. Thus, intervention planning towards the identified determinants may be needed to reduce neonatal birth asphyxia.
Isolation and Identification of Streptococcus suis from sick pigs in Bali, Indonesia
Authors: Besung Nengah I. K. , Suarjana Gusti Ketut , Agustina Karang Kadek , Winaya Oka Ida Bagus , Soeharsono Hamong , Suwiti Ketut Ni , Mahardika Gusti Ngurah
Published: July 2019

Background
Streptococcus suis (S. suis) is a causative agent for various syndromes in pigs. It can be transmitted to humans with typical symptoms of meningitis and death. Data in Bali Referral Hospital showed more than 40 confirmed human cases of S. suis meningitis in 2014. Cases of S. suis infection in pigs have never been confirmed in the province. Here we provide evidence of the bacteria in sick pigs in that world tourist destination province.
Results
The S. suis was confirmed in eight out of 30 cases. Prominent histopathological lesions of confirmed cases were meningitis, endocarditis, pericarditis, bronchopneumonia, enteritis, and glomerulonephritis. The dominant inflammatory cells were neutrophils and macrophages.
Conclusions
Streptococcus suis has been confirmed in sick pig in Bali, Indonesia. Further research is needed to understand the risk factor of human infection. Awareness of the community on the risk of contracting S. suis is needed to prevent human infections.
Does the shoe really fit? Characterising ill-fitting footwear among community dwelling older adults: an observational cross-sectional study
Authors: O'Rourke Brian , Walsh Mary E , Brophy Rachael , Vallely Shanice , Murphy Niamh , Conroy Bronagh , Cunningham Conal , Horgan Frances
Published: July 2019

Background

Falls in older people are common and can result in loss of confidence, fear of falling, restriction in activity and loss of independence. Causes of falls are multi-factorial and include extrinsic factors such as unsafe footwear. Inappropriate footwear may increase the risk of falls. There is a paucity of research assessing the footwear characteristics among older people who are at high risk of falls, internationally and in the Irish setting. The aim of this study was to examine the proportion of older adults attending a geriatric day hospital in Ireland who were wearing incorrectly sized shoes.

Methods

A consecutive sample of 111 older adults aged 60 years and over attending a geriatric day hospital in a large Irish teaching hospital was recruited. Demographic data including age, mobility, medications, use of glasses, social support, footwear worn at home and falls history were recorded. Shoe size and foot length were measured in millimetres using an internal shoe gauge and SATRA shoe size stick, respectively. Subjects’ self-reported shoe size was recorded. Footwear was assessed using the Footwear Assessment Form (FAF). A Timed Up and Go (TUG) score was recorded. Participation was assessed using the Nottingham Extended Activities of Daily Living (NEADL) Scale. Those with shoes fitting on at least one foot were compared to those with ill-fitting footwear on both feet using Chi-square tests, T-tests or Mann–Whitney U tests.

Results

72% of participants were wearing footwear that did not fit correctly on both feet according to our definition based on previous literature. Only 6% were wearing footwear that fitted correctly on both feet. 67% wore slippers at home. 90% had shoes with smooth, partly worn or fully worn sole treading. Participant age, TUG score and NEADL score were not associated with ill-fitting footwear.

Conclusions

Wearing incorrectly fitting shoes and shoes with unsafe features is common among older adults attending geriatric day services. The large number of participants who reported wearing slippers at home is also an important finding. Ill-fitting footwear and slippers are risk factors for falls thus warranting further investigation to help guide future falls prevention services at day hospitals.
Does GRASP affect DCE-MRI for assessing response to neoadjuvant chemotherapy in patients with esophageal cancer?
Authors: Lu Yanan , Ma Ling , QIN Jianjun , Wang Zhaoqi , Guo Jia , Zhao Yan , Zhang Hongkai , Yan Xu , Liu Hui , Li Hailiang , Qu Jinrong
Published: July 2019

Purpose
To compare the value of two dynamic contrast-enhanced Magnetic Resonance Images (DCE-MRI) reconstruction approaches, namely golden-angle radial sparse parallel (GRASP) and view-sharing with golden-angle radial profile (VS-GR) reconstruction, and explore their values in assessing response to neoadjuvant chemotherapy (nCT) in esophageal cancer (EC).
Methods
The study prospectively enrolled EC patients receiving nCT before surgery. DCE-MRI scanning was performed after nCT and within 1 week before surgery. Chemotherapy response was assessed according to Tumor Regression Grade (TRG), and patients were stratified into a responsive group (TRG1+2) and a non-responsive group (TRG3+4+5). Wilcoxon test was utilized for comparing GRASP and VS-GR reconstruction, and Kruskal-Wallis and Mann-Whitney test was performed for each parameter to assess response, and Spearman test was performed for analyzing correlation between parameters and TRGs, as well as responder and non-responder.
Results
Among the 64 patients included in this cohort (52 male, 12 female; average age of 59.1±7.9 years), 4 patients showed TRG1, 4 patients were TRG2, 7 patients were TRG3, 11 patients were TRG4, and 38 patients were TRG5. They were stratified into 8 responders and 56 non-responders.
A total of 15 parameters were calculated from each tumor. With VSGR, 10/15 parameters significantly correlated with TRG and response groups. Of these, only AUCmax showed moderate correlation with TRG, 7 showed low correlation and 2 showed negligible correlation with TRG. 8 showed low correlation and 2 showed negligible correlation with response groups. With GRASP, 13/15 parameters significantly correlated with TRG and response groups. Of these, 10 showed low correlation and 3 showed negligible correlation with TRG. 11 showed low correlation and 2 showed negligible correlation with TRG.

Conclusion
In patients with esophageal cancer on neoadjuvant chemotherapy, several parameters can differentiate responders from non-responders, using both GRASP and VS-GR techniques. GRASP may be able to better differentiate these two groups compared to VS-GR.
Factors affecting weight and body composition in childhood cancer survivors – cross sectional study
Authors: Sawicka-Zukowska Malgorzata , Łuczyński Włodzimierz , Dobroch Jakub , Krawczuk-Rybak Maryna
Published: July 2019

Background

Due to improved efficacy of antitumour treatment in the general population, there are increasingly more childhood cancer survivors. However, some of these survivors are at risk of distant complications including cardiovascular disease. We aimed to examine the risk of overweight/obesity and abnormal body composition in a large group of patients from our paediatric oncology centre.

Method

We used anthropometric methods and electrical bioimpedance to assess these features, and then determined their association with disease and treatment.

Results

We found patients treated for leukaemia/lymphoma (especially boys) had significantly higher rates of overweight/obesity compared to the other patient groups. In contrast, overweight/obesity was more common in girls among patients treated for solid tumours. Patients treated for leukaemia/lymphoma were characterized by a higher body fat content compared to those treated for solid tumours and controls. During treatment for cancer patients had a higher percentage of muscle mass deficiency compared to those in the control group. Our regression analysis showed time from completion of treatment, gender, and type of therapy (radiotherapy, megachemotherapy) were associated with body weight and body composition including fat and muscle content.

Conclusions

We recommend pediatricians and general practitioners should actively try to detect and prevent cardiovascular disease among childhood cancer survivors.
VOPP1 promotes hepatocellular carcinoma proliferation through MAPK14 and RPS6KB1
Authors: Dai Haojiang , Hu Peng , Wang Binfeng , Han Qiuyue , Xu Yongfu , Lv Shangdong , Zhu Yu , Gan Meifu , Zhou Weijie , Fang Zheping , Zhang Wenlong
Published: July 2019

Background: The present study aimed to investigate the role of VOPP1 in hepatocellular carcinoma (HCC).
Methods: Immunohistochemistry(IHC), Western blot and Reverse-transcription polymerase chain reaction (RT-PCR) were used to analyze the expression of VOPP1 protein, the expression of VOPP1, MAPK14, RPS6KB1, CYLD and TWIST1 and the mRNA expression of VOPP1, MAPK14, RPS6KB1, CYLD and TWIST1. The cell proliferation and apoptosis were tested using Celigo cell imaging analyzer and annexin V-APC apoptosis detection kit respectively. Colony formation and tumor xenograft assays was performed to understand their roles in tumorigenicity.
Results: The expression of VOPP1 in HCC samples was higher than that in adjacent noncancerous tissues by immunohistochemistry. In addition, the deletion of VOPP1 using shRNA inhibited cell proliferation and tumour growth, and induced cell apoptosis in vitro and in vivo. Furthermore, VOPP1 silencing decreased the expression of MAPK14 and RPS6KB1, indicating that the MAPK and mTOR signalling pathways might be involved in VOPP1-mediated cancer cell proliferation.
Conclusion: The present data indicates that VOPP1 may play an important role in the progression of HCC by targeting the MAPK and mTOR signalling pathways, and that VOPP1 may potentially be a candidate as a novel molecular target for HCC therapy.
PREST: Pain REduction with bone metastases STereotactic radiotherapy: A phase III randomized multicentric trial
Authors: Cellini Francesco , Manfrida Stefania , Deodato Francesco , Cilla Savino , Maranzano Ernesto , Pergolizzi Stefano , Arcidiacono Fabio , Franco Rossella Di , Pastore Francesco , Muto Matteo , Borzillo Valentina , Donati Costanza , Siepe Giambattista , Parisi Salvatore , Salatino Antonia , D'Agostino Antonino , Montesi Giampaolo , Santacaterina Anna , Fusco Vincenzo , Santarelli Mario , Gambacorta Maria Antonietta , Corvò Renzo , Morganti Alessio Giuseppe , Masiello Valeria , Muto Paolo , Valentini Vincenzo
Published: July 2019

Background

Palliative antalgic treatments represent an issue for clinical management and a challenge for scientific research. Radiotherapy (RT) plays a central role. Techniques such as stereotactic body radiotherapy (SBRT) were largely investigated in several phase 2 studies with good symptom response, becoming widely adopted. Still is lacking evidence from randomized, direct comparison of RT and SBRT.

Methods/Design

The PREST trial was designed as an interventional study without medicinal, randomized 1:1, open-label, multicentric, phase 3. Inclusion criteria: painful spinal bone metastases presenting pain level >4 (or >1 if assuming analgesic) at numeric rating scale (NRS); expected intermediate/high prognosis (superior to 6 months) according to the Mizumoto prognostic score; low spine instability neoplastic score (SINS) sores (<7); magnetic resonance imaging (MRI) assessment of the bulky lesion. Patients will be assigned to either standard conventional radiotherapy administering 4 Gy x5 fractions (fx) to whole involved vertebra or SBRT by intensity modulated radiotherapy with simultaneous integrated boost (IMRT-SIB) administering 7 Gy x3 fx (to the whole involved vertebra) + 10 Gy x3 fx on the macroscopic disease (Gross Tumor Volume -GTV). In the experimental arm, the GTV will be contoured by registration with baseline MRI.

Discussion

Primary endpoint is overall pain reduction, defined in term of variation between baseline and 3-month evaluation; pain will be measured by Numeric Rating Scale (NRS) score. Secondary endpoints include: pain control duration; retreatment rates (after a minimum interval of 1 month); local control assessed with RECIST Criteria; symptom progression free survival; progression free survival; overall survival and quality of life (at 0, 30 and 90 days). Accrual of 330 lesions is planned. Experimental arm is expected to improve overall pain response rates of 15% respect to standard arm (60% according to Chow et al 2012).