bluuebunny/crossref_metadata_2025 huggingface dataset:
Boundary metric of Epstein-Penner convex hull and discrete conformality
Authors: Nie Xin
Published: September 2023

The Epstein-Penner convex hull construction associates to every decorated punctured hyperbolic surface a polyhedral convex body in the Minkowski space. It works in the de Sitter and anti-de Sitter spaces as well. In these three spaces, the quotient of the spacelike boundary part of the convex body has an induced Euclidean, spherical and hyperbolic metric, respectively, with conical singularities. We show that this gives a bijection from the decorated Teichm\"uller space to a moduli space of such metrics in the Euclidean and hyperbolic cases, as well as a bijection between specific subspaces of them in the spherical case. Moreover, varying the decoration of a fixed hyperbolic surface corresponds to a discrete conformal change of the metric. This gives a new $3$-dimensional interpretation of discrete conformality which is in a sense inverse to the Bobenko-Pinkall-Springborn interpretation.
A Comparative Study of Ultrasonography (USG) and Computed Tomography for Detecting Ureteric Calculi in Patients with Acute Flank Pain, and Analysis of Factors Influencing Ultrasound Detection Rates: Findings from a Tertiary Hospital in Nepal
Authors: Khatiwada Bishnu , Mahat Asim , Yadav Gopal Kumar , Duwadi Bikash , Mishra Upama , Bhusal Amrit , Yadav Priti , Khadka Hensan
Published: September 2023

Introduction:
To address the unmet clinical need, we aimed to analyze the roles of ultrasound (US) and computed tomography (CT) scans in evaluating ureteric calculi in patients with acute flank pain. Additionally, we assessed the factors affecting the US detection rates in the same group of patients.
Methods
We conducted a cross-sectional study using purposive sampling, involving 87 participants who presented with acute flank pain at a tertiary hospital in Nepal. Ethical clearance was obtained from the institutional review board.
Results
Among the 87 patients presenting with acute flank pain, the majority were male (51, 58.62%). Of the 78 cases with CT-detected ureteric calculi, the most common locations were distal ureter (23/78, 29.49%), followed by proximal ureter (21/78, 26.92%), and pelvic-ureteric junction (PUJ) (20/78, 25.64%). Ultrasound demonstrated varying sensitivities for detecting ureteric calculi: 95.00% for PUJ, 100.00% for vesicoureteric junction (VUJ), 66.67% for proximal ureter, and 56.52% for distal ureter calculi. The highest sensitivity was observed for calculi greater than 15 mm (100%), followed by 10.1 to 15 mm (77.7%). Overall, ultrasound exhibited a sensitivity of 76.92%, a specificity of 100%, and an accuracy rate of 79.31% in detecting calculi. Notably, patients with hematuria had significantly higher odds of ultrasound-detected ureteric calculi (OR: 36.68, 4.54-296.26, P < 0.01) than those without hematuria. However, age, hydronephrosis, calculi location, and laterality were not found to be significantly associated with ultrasound detection.
Conclusions
Due to its good sensitivity, ultrasound can serve as the first-line investigation for individuals experiencing acute flank pain, given its cost-effectiveness and radiation-free nature when compared to CT scans. CT scans should be reserved for patients exhibiting clinical symptoms of severe colic who have previously undergone a negative ultrasound (USG).
Adverse Childhood Experiences and Maladaptive Daydreaming
Authors: Moment Lauren
Published: September 2023

This paper explores the concept of maladaptive daydreaming, a phenomenon characterized by excessive and immersive daydreaming that interferes with daily functioning. While normative daydreaming can be an adaptive behavior that may contribute to planning, future goals, and creativity, maladaptive daydreaming can lead to poor academic, interpersonal, and professional performance and increased social isolation. The study found a moderate positive correlation between maladaptive daydreaming and adverse childhood experiences, suggesting that childhood trauma may contribute to the development of maladaptive daydreaming. Maladaptive daydreaming was also significantly positively correlated with depression and anxiety, indicating potential comorbidity with these mental health concerns. The study highlights the need for increased awareness and understanding of maladaptive daydreaming as a potential mental health concern, particularly for individuals who have experienced adverse childhood experiences. Interventions aimed at improving coping skills and addressing underlying trauma may be beneficial in reducing the negative impact of maladaptive daydreaming on daily functioning.
Investigating Medical Students' Attitudes Towards Patient’s Bills of Rights: Implications for Ethical Care
Authors: Abdollahi Amirsaleh , Varaki Alireza Karimi , Frouzanian Mehran , Yousefi Mohammad , Shamshiriyan Mostafa , Rezaee Ali , Darabinia Morteza , Alipour Abbas
Published: September 2023

Introduction
The provision of ethical care is a critical component of the medical profession, and adherence to the patient's bill of rights is essential to ethical care. This study aimed to investigate medical students’ attitudes toward the provisions of the patient's ethical charter.
Methods
A cross-sectional descriptive-analytical study was conducted between March 2022 to July 2022 among several medical students in the 1st to 10th semesters at Mazandaran University of Medical Sciences. Data were collected using valid and reliable questionnaires containing 22 questions about the patient's bill of rights provisions. The questionnaire scoring scale was based on the five-point Likert scale. Students' views were classified into three levels: favorable, relatively favorable, and unfavorable.
Results
230 medical students participated in the study, with a mean age of 21.96 ± 2.89, and 37% were women. The average student had a relatively favorable attitude toward the patient's Bill of Rights provisions. There were no significant differences between men and women or between students who had related programs about the patient's bill of rights and those who did not. The correlation between age and semester by attitude score towards the patient's right charter showed a significant relationship. With increasing age, the attitude toward patient rights standards worsened. Higher-semester students were more unfavorable toward the patients' bill of rights provision.
Conclusion
The study findings suggest that implementing medical courses and programs related to the patient's bill of rights could be more effective. Medical students' attitudes towards the patient's ethical charter worsen with increasing age and academic term. Further studies are required to identify the reasons behind this trend and improve the implementation of medical courses and programs related to the patient's bill of rights.
Ebola Virus Disease: Knowledge, Attitude and Perception - The Case of Uganda
Authors: KIBUUKA RONALD , Kagoya Enid Kawala , Nsubuga Allan. G. , Ahaisibwe Bonaventure , Atuhairwe Irene , Nakatudde Prossy , Kizito Prisca , Jesca Atugonza , Okibure Ambrose , Okello Francis , Nyangoma Faith , Nakawuka Bety , Nakabaale Mark , Nakawuki Ashley , Namara Racheal , Catherine Asiimwe W. , Tamale Elvis , Akol Patrick , Nabwire Lilian , Waako Paul , Wandabwa Julius , Musaba Milton , Barugahare Banson
Published: September 2023

Introduction
Ebola virus disease (EVD) is a severe hemorrhagic disease caused by the Ebola Virus. The EVD is highly infectious with a high fatality rate. Uganda has experienced multiple Ebola outbreaks. To address the need for renewed engagement between the government and community, this study aimed to assess knowledge, attitudes, and preventive practices towards EVD in different regions of Uganda.
Objectives
To determine the level of knowledge, attitude and prevention practices towards the Ebola Virus in the different regions of Uganda.
Methods
A descriptive community-based cross-sectional design was conducted. The study implored a quantitative approach. Participants were randomly assessed of their knowledge, attitude and prevention of the EVD. Data was analyzed with Stata 15.
Results
The study enrolled 737 community members. The majority of the community members demonstrated good knowledge levels of EVD. Participants who obtained information from social media had higher knowledge levels across the respective study regions of the country; Mbale (OR = 9.8, CI: 2.2–43.5, p = 0.03) and Mbarara (OR = 8.6, CI: 4.0-18.45, P = 0.001) cities. However, in Lira city, the association between social media and knowledge levels was not statistically significant. The use of television as an information source significantly positively affected knowledge levels in Mbale city, Eastern region (OR = 4.0, CI: 1.6–10.1, P = 0.004). Health workers exhibited significantly higher knowledge compared to the others (OR = 8.9, CI: 1.1–69.6, P = 0.038) Knowing how to approach a suspected case, had a significant level in Mbale city, Eastern region (OR = 8.6, CI: 2.4–30.4, P = 0.001). Similarly, knowing how to use PPE was associated with higher levels in Lira city north Eastern region (OR = 2.0, CI: 1.1–3.3) P = 0.021. The majority both females (94.4%, 91.7% and males (88.9%, 90%) agreed to the isolation of the case and the family respectively avoid the risk of infection and death, which also led to a discriminatory attitude towards survivors and a distrust of EVD treatment. All participants 74.3% and 76.9% female and male perceived the Ebola treatment as very expensive.
Conclusion
Our results are in tandem with previous reports. we found that urban communities are more knowledgeable and have better attitudes towards pandemic outbreaks, though this varies from region to region. Public perceptions, community engagement and social media may be useful tools in mapping knowledge and awareness strategies for disease outbreaks.
The Experiences and Perceptions of Campus Resource Utilization by University Students with Childhood Domestic Violence Exposure Histories
Authors: Allen Amie , Ravi Kristen , Haselschwerdt Megan , Niederhauser Victoria
Published: September 2023

Objective: The purpose of this study was to examine the campus resource utilization experiences of university students with childhood domestic violence exposure (CDV) histories.
Participants: 368 students attending a public, 4-year university in the Southeastern United States.
Methods: Participants completed a web-based survey with variables including CDV, campus resource utilization and perceptions of said resources, and participant resource suggestions.
Results: Most students utilized at least one health-related campus resource, with the student health and counseling centers as the most common and helpful. Suggested areas for institutional and service provider growth include enhanced advertisement and accessibility for existing resources and added support groups.
Conclusions: College campuses provide unique opportunities to support young adults with CDV histories. Tailoring programming to students with CDV histories has the potential to improve student's success in and beyond college.
Clinical spectrum of adult-onset Still’s disease in patients presenting at a tertiary care hospital in Pakistan: A 16-year retrospective descriptive study
Authors: Riaz Mehmood , Baqir Syed Mujtaba , Isra Ahmed , Karim Zohair , Arshad Ainan
Published: September 2023

Introduction: Adult-onset Still's Disease (AOSD) is a rare systemic auto-inflammatory disorder with limited available data and regional variations in presentation. This study aims to shed light on the clinical and laboratory spectrum and associated complications of AOSD patients at a tertiary care center. The goal is to facilitate early diagnosis and management in cases lacking characteristic features.
Methods: We conducted a retrospective review of patient records from January 2005 to February 2021, utilizing the Yamaguchi criteria for AOSD diagnosis. Clinical symptoms, laboratory values, therapeutic approaches and complications were analyzed. Descriptive statistics were employed to illustrate disease patterns.
Results: The study included patients with a mean age of 37.6 years, with a male-to-female ratio of 3:5. Fever and arthralgia were prevalent in 100% of cases, while a salmon-colored rash was observed in 62.5%, and leukocytosis in 75%. Additional symptoms included sore throat and recent lymphadenopathy in 37.5%, hepatomegaly and/or splenomegaly on imaging in 50%, and abnormal liver function tests in 87.5% cases. Steroids were the primary first-line treatment. Notably, most patients did not exhibit the common complications previously reported in AOSD.
Conclusion: The clinical findings in our study closely resemble those reported in other regions, emphasizing the need for a comprehensive analysis of AOSD. This study underscores the importance of considering AOSD as a potential diagnosis, even in atypical presentations, to enhance patient care by minimizing delays in diagnosis and enabling prompt management.
Key points
• This study presents the first national data on AOSD in Pakistan
• AOSD mostly affects younger adults, with a mean age of 37.6 years
• Common AOSD symptoms include fever, arthralgia, leukocytosis, high ferritin levels, and abnormal liver function, but the rash's prevalence varies by region.
Insights on the potential of RNA-Seq on improving pomological traits of African indigenous fruit trees: a mini review
Authors: Chaibva Paul , Mugehu Edith , Manjeru Pepukai
Published: September 2023

Fruit tree improvement has taken great strides by roping in improved and efficient biotechnological tools to increase fruit yield and quality to meet local and export demands. For the past decade, the RNA-Seq tool has successfully been used in fruit tree improvement programs to identify genes, dissect complex traits, and understand different molecular pathways and differential expression of genes. However, despite their growing importance in food and nutrition security, medicinal uses, and climate change mitigation strategies, very little has been done to improve the pomological traits of African indigenous fruits, especially at the molecular level. African indigenous fruit trees exhibit unexplained variation in flowering, fruit load, fruit size, fruit ripening, fruit taste, fruit nutritional composition and shelf-life. The booming local commercial companies and export markets are demanding consistent quality indigenous fruits. This has necessitated the need for fast and effective tools that will hasten the understanding and improvement of fruiting qualities. The improvement of fruiting and fruit qualities will go a long way in accelerating the domestication and commercialization of African indigenous fruit trees. This review paper gives molecular biology insights on how RNA-Seq has been successfully used in fruit improvement of exotic fruits through gene identification, comparative transcriptome analysis under different conditions, and understanding molecular pathways that influence important pomological traits. The review article also unearths opportunities where RNA-Seq can improve our knowledge and improvement of undesirable traits common in African indigenous fruits
Effect of positive organizational behavior on subjective well-being in the workplace in the tourism sector of Jordan
Authors: Farajat Jihad , A. Salah Ali
Published: September 2023

Employee subjective well-being, which contributes to work stability, increases productivity, and in turn improves the performance of both employees and the organization, is critical in modern business organizations for a variety of reasons that affect the performance and sustainability of those organizations, as well as the numerous benefits they achieve.The purpose of this study is to discover the impact of positive organizational behavior on the subjective well-being of employees in Jordanian tourism industry. The analytical-descriptive methodology was used to attain the study’s goal. The sample consisted of 392 workers of Jordanian tourism organizations (22 companies) within the upper and middle administrative levels, who were chosen using a simple random procedure. The questionnaire that included items to measure the dimensions of independent and dependent variables was distributed to them.The study concluded that there is a medium level of positive organizational behavior and subjective well-being in the workplace for the study sample. All dimensions of positive organizational behavior (self-efficacy, optimism, hope, and flexibility) have a statistically significant effect on subjective well-being. That is, the higher the level of positive organizational behavior, the higher the subjective well-being of workers.
AcknowledgmentThis study is funded by the Al-Hussein Bin Talal University, fund decision number (393/2021).
Insights into Metabolic Engineering of Bioactive Molecules in Tetrastigma
Hemsleyanum Diels & Gilg: A Traditional Medicinal Herb
Authors: Ajeesh Krishna T.P. , Maharajan T. , Adarsh Krishna T.P. , Antony Ceasar S.
Published: September 2023

Plants are a vital source of bioactive molecules for various drug development processes.
Tetrastigma hemsleyanum is one of the endangered medicinal plant species well known to the
world due to its wide range of therapeutic effects. Many bioactive molecules have been identified
from this plant, including many classes of secondary metabolites such as flavonoids, phenols, terpenoids,
steroids, alkaloids, etc. Due to its slow growth, it usually takes 3-5 years to meet commercial
medicinal materials for this plant. Also, T. hemsleyanum contains low amounts of specific bioactive
compounds, which are challenging to isolate easily. Currently, scientists are attempting to increase
bioactive molecules' production from medicinal plants in different ways or to synthesize
them chemically. The genomic tools helped to understand medicinal plants' genome organization
and led to manipulating genes responsible for various biosynthesis pathways. Metabolic engineering
has made it possible to enhance the production of secondary metabolites by introducing manipulated
biosynthetic pathways to attain high levels of desirable bioactive molecules. Metabolic
engineering is a promising approach for improving the production of secondary metabolites over a
short time period. In this review, we have highlighted the scope of various biotechnological approaches
for metabolic engineering to enhance the production of secondary metabolites for pharmaceutical
applications in T. hemsleyanum. Also, we summarized the progress made in metabolic engineering
for bioactive molecule enhancement in T. hemsleyanum. It may lead to reducing the destruction
of the natural habitat of T. hemsleyanum and conserving them through the cost-effective
production of bioactive molecules in the future.
Computer-Aided Drug Discovery Studies in Ethiopian Plant Species
Authors: Sekaran Surya , Eswaramoorthy Rajalakshmanan , Doble Mukesh , Sathish kumar Palanivel , Kumar Ramachandran Sathish
Published: September 2023

Since ancient times, plants with therapeutic properties play a major role and
are used as medicine by several groups of people all over the world. Ethiopia can be
considered a hub of medicinal plants due to their diverse species and traditional usage
by the local people. Medicinal plants in Ethiopia hold high therapeutic value and hence,
most of them are preserved and saved from extinction. Also, most of the plants are yet
to be studied due to a lack of documentation and experimental validation. Secondary
metabolites from these plants possess numerous pharmacologically active compounds.
Computer-aided drug discovery using Artificial Intelligence and high throughput
technologies saves time and is more cost-efficient than traditional clinical studies. In
this chapter, we discuss the computational studies done on ten important Ethiopian
medicinal plants that have antioxidant, antimicrobial, anticancer and antidiabetic
properties using phytochemical analysis and In-silico approach for plant-based drug
development, which could serve as a potential pharmacological lead against different
disease targets.
Coping Strategies employed by Muslim Academia during Covid-19: A narrative review
Authors: Aboo Bakar Rofiza , Tazijan Farina Nozakiah , Sudarsono Sudarsono , Ikhsanudin Ikhsanudin
Published: September 2023

The global educational scenario has undergone a major transformation due to the COVID-19 pandemic, leading to substantial conflict and disturbances in the process of imparting and acquiring knowledge. The scarcity of studies on Muslim academia’s coping mechanisms amidst the COVID-19 outbreak highlights the necessity to investigate their distinct encounters.  Drawing on existing literature, this narrative review explores the Islamic-based coping strategies they employed. Educators, mental health practitioners, and other stakeholders may acknowledge the significance of these coping strategies and integrate them into mental health and educational programmes to aid the Muslim academia and alike amidst the pandemic and beyond.
Factors Affecting the Eligibility of Zakat Assistance to University Students during COVID-19: A case study in Universiti Teknologi MARA (UiTM)
Authors: Abdul Aziz Azlan , Mohamad Nor Nor Azriani , Wan Shahidan Wan Nurshazelin , Mohamad Siti Nor Nadrah
Published: September 2023

The Unit Zakat, Sedekah & Wakaf (ZAWAF) Universiti Teknologi MARA (UiTM) Cawangan Perlis has offered Islamic financial assistance such as Zakat Sara Diri, Zakat Yuran Pengajian, and Zakat Komputer Riba to students during online pandemic COVID-19. Therefore, ZAWAF needs to identify factors contributing to the eligibility for Zakat assistance. The Binary Logistic regression model was used to determine the significant factors. Stepwise selection procedures are used to yield the most appropriate regression equation. Wald statistics were used to determine the significant factors. Four factors significantly are the Head of a family's monthly income, mother's monthly income, family dependents, and gender.
Evaluación de resistencia en plátanos ante la marchitez de las musáceas por Foc R4T
Authors: Rodríguez-Yzquierdo Gustavo Adolfo , Soto-Suárez Mauricio , Betancourt-Vásquez Mónica
Published: September 2023

La marchitez de las musáceas producida por Fusarium oxysporum f. sp. cubense - Foc se considera la enfermedad más destructiva en musáceas; su agente causal presenta una gran diversidad genética y patogénica. Las razas han sido identificadas por la patogenicidad de las poblaciones de Foc a determinados cultivares. La Raza 1 afecta a los cultivares Gros Michel (AAA), Manzano (AAB) y los del subgrupo Pisang Awak (ABB); además, es reconocida porque en América Latina destruyó más de 378.000 ha de Gros Michel.
Consumo y regulación sanitaria de suplementos alimenticios para el control de peso. Un estudio en Xalapa, México
Authors: Suárez-Améndola Pablo Martín , Gutiérrez-Alba Gaudencio , Gogeascoechea-Trejo María del Carmen
Published: September 2023

En México, la oferta de suplementos alimenticios con fines terapéuticos o de rehabilitación no está permitida por la ley; no obstante, se observa que estos productos se publicitan para fines distintos a los permitidos legalmente, sobre todo en la Internet y por medio de agentes no regularizados. El objetivo del estudio es identificar la prevalencia de consumo de suplementos alimenticios para el control de peso y su asociación con características sociodemográficas en población adulta, así como aportar elementos de análisis de la regulación sanitaria ejercida sobre dichos productos; Materiales y métodos: Estudio transversal analítico realizado en unidades urbanas del primer nivel de atención. Se encuestó a 154 pacientes adultos diagnosticados con sobrepeso u obesidad que acudieron a consulta externa. Las variables analizadas fueron el consumo de suplementos alimenticios, edad, sexo, escolaridad, ocupación y nivel socioeconómico. En el análisis se utilizó la prueba de chi cuadrado para identificar asociación entre variables; Resultados: La prevalencia de consumo de suplementos alimenticios para el control de peso fue de 24.1%. Las variables edad y escolaridad mostraron asociación con el consumo; Conclusiones: La prevalencia encontrada resalta la necesidad de una regulación sanitaria más eficiente. La educación nutriológica y la colaboración de sociedades y gobiernos para la implementación de políticas públicas adecuadas se identifican como estrategias para la disminución en la oferta y consumo de estos productos.
Palabras clave: obesidad, prevalencia, regulación sanitaria, sobrepeso, suplementos alimenticios
Termografía infrarroja una herramienta exacta para detectar infecciones en úlceras diabéticas
Authors: Rodriguez-Alonso Dante , Benites castillo Santiago , Milly Otiniano Nélida , Chian Garcia Ana
Published: September 2023

Determinar la exactitud de la termografía infrarroja como herramienta de diagnóstico para detectar infecciones en úlceras diabéticas en comparación con el diagnóstico clínico según la Infectious Diseases Society of America (IDSA).Se reclutaron a 80 pacientes diabéticos con úlceras sospechosas de infección y realizaron tanto un examen clínico como una termografía infrarroja de las lesiones. El diagnóstico clínico según la IDSA se basó en la presencia de varios síntomas y signos, mientras que la infección termográfica se definió como una diferencia de temperatura de al menos 3°C entre la lesión y el tejido circundante.Los rresultados mostraron que la exactitud de la termografía infrarroja fue del 91%, lo que indica que esta herramienta puede ser útil para detectar infecciones de manera precoz y prevenir complicaciones graves en el pie diabético, como la sepsis y la amputación. Este estudio sugiere que la termografía infrarroja podría ser una herramienta complementaria útil para el diagnóstico de infecciones en úlceras diabéticas en la atención primaria.
Keywords: Exactitud diagsnotica ,imagen termografica ,ulcera diabetica , infeccion
Exéresis de aneurisma gigante a nivel de fistula arteriovenosa
Authors: Valdés Dupeyrón Osvaldo , Paz y Miño Intriago Walther Zhukov , Espinales Casanova Lidia , Alvear Toala Lisbeth Estefania , González Robles Javier , Suarez Fernández Juan Carlos , Lois Mendoza Natacha , Chancay Mendoza Andrea Patricia
Published: September 2023

Un aneurisma a nivel de fistula arteriovenosa es una complicación crónica. Los riesgos de trombosis, ruptura y hemorragia masiva son directamente proporcionales al tamaño de la misma. El manejo precoz de los aneurismas relacionado con fistulas arteriovenosas es crucial para prevenir efectos adversos potencialmente mortales. Masculino de 57 años de edad con antecedentes de hipertensión arterial, insuficiencia renal crónica en diálisis trisemanal, que se dializa por fistula arteriovenosa humero cefálica izquierda. Se decide cirugía de cierre de fistula con control proximal de la arteria humeral, cuello del aneurisma. Se liberan las adherencias del aneurisma con estructuras profundas a nivel del codo, se realiza doble ligadura a nivel del cuello del aneurisma, comprobando pulsos distales en arteria radial y cubital. Se repara la vena cefálica y se reseca todo el aneurisma.
Keywords: Aneurisma gigante, fistula arteriovenosa, , hemodiálisis
Iterative Patient Testing of a Stimuli-Responsive Swallowing Activity Sensor to Promote Extended User Engagement During the First Year After Radiation: Multiphase Remote and In-Person Observational Cohort Study
Authors: Shinn Eileen H , Garden Adam S , Peterson Susan K , Leupi Dylan J , Chen Minxing , Blau Rachel , Becerra Laura , Rafeedi Tarek , Ramirez Julian , Rodriquez Daniel , VanFossen Finley , Zehner Sydney , Mercier Patrick P , Wang Joseph , Hutcheson Kate , Hanna Ehab , Lipomi Darren J
Published: September 2023

Background

Frequent sensor-assisted monitoring of changes in swallowing function may help improve detection of radiation-associated dysphagia before it becomes permanent. While our group has prototyped an epidermal strain/surface electromyography sensor that can detect minute changes in swallowing muscle movement, it is unknown whether patients with head and neck cancer would be willing to wear such a device at home after radiation for several months.

Objective

We iteratively assessed patients’ design preferences and perceived barriers to long-term use of the prototype sensor.

Methods

In study 1 (questionnaire only), survivors of pharyngeal cancer who were 3-5 years post treatment and part of a larger prospective study were asked their design preferences for a hypothetical throat sensor and rated their willingness to use the sensor at home during the first year after radiation. In studies 2 and 3 (iterative user testing), patients with and survivors of head and neck cancer attending visits at MD Anderson’s Head and Neck Cancer Center were recruited for two rounds of on-throat testing with prototype sensors while completing a series of swallowing tasks. Afterward, participants were asked about their willingness to use the sensor during the first year post radiation. In study 2, patients also rated the sensor’s ease of use and comfort, whereas in study 3, preferences were elicited regarding haptic feedback.

Results

The majority of respondents in study 1 (116/138, 84%) were willing to wear the sensor 9 months after radiation, and participant willingness rates were similar in studies 2 (10/14, 71.4%) and 3 (12/14, 85.7%). The most prevalent reasons for participants’ unwillingness to wear the sensor were 9 months being excessive, unwanted increase in responsibility, and feeling self-conscious. Across all three studies, the sensor’s ability to detect developing dysphagia increased willingness the most compared to its appearance and ability to increase adherence to preventive speech pathology exercises. Direct haptic signaling was also rated highly, especially to indicate correct sensor placement and swallowing exercise performance.

Conclusions

Patients and survivors were receptive to the idea of wearing a personalized risk sensor for an extended period during the first year after radiation, although this may have been limited to well-educated non-Hispanic participants. A significant minority of patients expressed concern with various aspects of the sensor’s burden and its appearance.

Trial Registration

ClinicalTrials.gov NCT03010150; https://clinicaltrials.gov/study/NCT03010150
Multidrug-Resistant Strain ExPEC Isolat Asal Puyuh (Coturnix coturnix japonica)
Authors: Prihtiyantoro Wahyu , Purnomo Agus , . Sudarisman , . Khusnan
Published: September 2023

AbstractExtraintestinal Escherichia coli (ExPEC) causes colibacillosis in poultry, including quail. ExPEC is a pathogenic E. coli that causes colibacillosis outside the gastrointestinal tract of poultry, in the form of peritonitis, pericarditis, salpingitis, synovitis, osteomyelitis, septicemia, pneumonitis, nephritis, pleurisy, proventriculitis and ventriculitis. In poultry farming antibiotics are used to promote growth and egg production, prevention and treatment of bacterial infections. Antibiotic resistance is a new problem that arises in poultry farming. In this study, 24 isolates of ExPEC strain from quail were used. These isolates did not differentiate sorbitol in the MacConkey (SMAC) sorbitol test assay. Antibiotic resistance was tested based on the inhibition of bacterial growth on Muller Hinnton Agar (MHA) media. 10 types of antibiotics were used to observe their resistance in all isolates. Resistance to Amikacin (87.5%), Ampicillin (87.5%), Ciprofloxacin (100%), Clindamycin (95.83%), Cefoxacin (25.0%), Doxycycline (87.5%), Erythromycin (100%), Gentamicin (95.83%), Penicillin (95.83%) and Tetracycline (83.3%). The isolates had multidrug-resistance between 3 to 10 types of antibiotics. This study showed that ExPEC isolates from quail were resistant to the type of antibiotics tested, so that the use of antibiotics in quail culture should be limited to reduce and prevent the emergence of new antibiotic resistance. Keyword: Escherichia coli, sorbitol-negative, quail, antibiotics resistance
Histological Analysis of Intestinum Tenue Rabbit Atherosclerosis Model
Authors: Budiariati Vista , . Ariana , Budipitojo Teguh
Published: September 2023

Atherosclerosis is a vascular disease that occurs as a result of a progressive inflammatory response in blood vessels. The method of inducing atherosclerosis with the rabbit animal model can be done by modifying the high-fat diet which can lead to hypercholesterolemia within a few days to the inducement of atheromatic lesions. This study was conducted to analyze the histology of the small intestine in a group of rabbits fed with standard diet and atherosclerosis model of rabbits fed with atherogenic diet. The results of morphometry analysis in the small intestine showed that the duodenal submucosa in group B was wider than group A, while the length of jejunal villi in group B was shorter than group A. Changes in the intestine were also followed by changes in the cell population. The number of goblet cells in the duodenum was less in group B compared to group A, but the number of goblet cells in the jejunum was actually more in group B than in group A. Further research is needed to determine the mechanism that causes this change so that it can support modeling of atherosclerosis in rabbits according to the pathophysiology and pathogenesis of diseases that occur in humans.
Suggestion for exhibition planning processor of science museum based on aesthetic experience
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Namju , Paik Seounghey
Published: September 2023

Objectives The study aimed at suggesting exhibition planning processor based on aesthetic experience for more creativity and educational effect through various scientific experience.
Methods The processor based on aesthetic experience was developed. Specialists for science museum had in-depth discussions, even 6 times.
Results Features of processor suggested in the study are as follows. First, The starting point of the processor is to clearly set the purpose of exhibition. Second, Only after satisfying feedback made each phase, it goes to next phase. Third, For effective exhibition planning, it is necessary to do comprehensive analysis over purpose of exhibition, estimation of demand, scenario, level of audience etc.
Conclusions This has meaning that exhibition planning based on aesthetic experience is shifted to exhibition method in science museum focusing on audience.
The Effects of the Parents' Cultural Orientation on the Father’s Parenting Participation
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Shin Keonho
Published: September 2023

Objectives The purpose of this study was to investigate the effects of the parents’ cultural orientation on the father’s parenting participation.
Methods Data on cultural orientation and parenting participation were collected from 310 couples whose children were enrolled in early childhood education centers, upon which correlation and multiple regression analyses were performed.
Results The findings of this study were as follows: First, collectivism of the father was positively correlated to the father’s parenting participation, but individualism of the father did not have any significant relationship with the father’s parenting participation. Second, individualism of the mother was positively correlated to the father’s parenting participation, but collectivism of the mother did not have any significant relationship with the father’s parenting participation.
Conclusions The above findings imply that parents’ cultural orientation is also a good predictor of the father’s parenting participation, and that the difference in cultural orientations between the two parents affect the father’s parenting participation. This research examines these results through the lens of previous papers and proposes the direction of follow-up studies to support paternal participation in parenting.
A Study on the Experience of Child Abuse Reporting Process of Childcare Center Staff Who discovered Parents' Child Abuse
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Shim Jin-ah , Chung Kayoun
Published: September 2023

Objectives This study aimed to investigate the experience of childcare center staff in the process of reporting child abuse after identifying parent-to-child abuse.
Methods The directors and staff at three childcare centers in Seoul, South Korea, who had experience discovering and reporting parent-to-child abuse were interviewed individually. The experience and process of child abuse reporting were analyzed inductively according to the steps of the Grounded Theory of Strauss & Corbin (1998).
Results The open coding of the childcare center staff experience and process of child abuse reporting resulted in six categories: ‘factors of child abuse reporting’, ‘situational context leading to child abuse reporting’, ‘challenges in child abuse reporting’, ‘reporting of child abuse by childcare center staff', ‘response strategy: internal vs. external’ , ‘result of child abuse reporting’. The axial coding enabled the construction of a paradigm model and a step-by-step reporting process. The selective coding enabled the integration and development of all categories based on the core category of conflict and change.
Conclusions The process of reporting child abuse by daycare center employees went through stages of shock, anger, conflict, compensation and regret, and change after reporting. Recognizing the significance of reporting to prevent child abuse and the need for institutional devices, this study discussed efficient support measures for mandatory child abuse reporters in the childcare sector.
Development and application of teaching and learning materials for middle school quadratic functions based on smartphone activity
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Kyeongsik
Published: September 2023

Objectives In this study, teaching and learning materials were developed for middle school students to explore
quadratic functions through smartphone-based activities. After the middle school students performed the activities,
the results of the activities were analyzed to find out whether they were motivated to learn mathematics and
what mathematical facts they found.
Methods Teaching and learning materials for quadratic function for exploration activities were developed using
GeoGebra for 5 2nd grade students at “A” middle school located in a small city. Afterwards, the developed teaching
and learning materials were applied to middle school students, and the students' results were analyzed in
terms of motivation, mathematical discovery, and content understanding.
Results After analyzing the middle school quadratic function curriculum and various textbooks, smartphone activity-
based quadratic function teaching and learning materials were developed. In addition, as a result of analyzing
the results of applying the developed teaching and learning materials to students, students were motivated to explore
quadratic functions using GeoGebra on their smartphones. In addition, while moving graphs of quadratic
function and observing the changes in function formula, the experience of reasoning about the translation of the
function was experienced. In addition, students gained more understanding and reasoning experience through
geometry-centered teaching and learning activities such as drawing points, drawing graphs, and moving them in
GeoGebra.
Conclusions Using the teaching-learning materials developed in this study, middle school students were able to
gain motivation for learning and infer and explore the contents of quadratic functions.
Relationship between the Major Selection Motivation and Professional Identity of Undergraduate Healthcare students in the Post COVID-19
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Woo Chung Hee , Shim Mi-So
Published: September 2023

Objectives The purpose of this study was conducted to estimate the mediating effect of the meaning of work in
the relationship between the major selection motivation and professional identity of undergraduate healthcare
students in the post-COVID-19 era.
Methods Data was collected using web-based questionnaires from April 10 to April 30, 2023. The data of 155 undergraduate
helthcare students was analyzed using hierarchical multiple regression.
Results The study found that the average score of professional identity among participants was 3.24 points.
Moreover, intrinsic factor (r=.37, p<.001) and external factor of major selection motivation (r=.27, p=.001) and the
meaning of work (r=.60, p<.001) showed a positive correlation with professional identity, respectively. Furthermore,
meaning of work showed a complete mediating effect respectively (Boot LLCI=.04, Boot ULCI=.11, Boot LLCI=.05,
Boot ULCI=.12) on the relationship between internal and external factors of the major selection motivation and
professional identity.
Conclusions Providing timely helthcare curriculum is necessary for enhancing meaning of work, which could promote
professional identity among undergraduate helthcare students.
The mediating effect of the principal's praising leadership recognized by the early childhood teachers between the turnover intention and organizational commitment of the early childhood teachers
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Jung-Eun
Published: September 2023

Objectives The purpose of this study is to examine the mediating effect ofthe principal's praising leadership recognized
by early childhood teachers between the turnover intention and organizational commitment of early childhood
teachers.
Methods To this end, a survey was conducted on 343 early childhood teachers in Busan, Ulsan, and Daegu. The
collected data were analyzed using descriptive statistics, correlation analysis, and the stepwise regression analysis,
utilizing the SPSS 21.0(ver.) statistical program. The mediating effect was examined using the Sobel test.
Results Firstly, significant correlations were found between overall turnover intentions and its sub-variables,
overall organizational commitment and its sub-variables, and overall praise leadership and its sub-domains.
Secondly, the perceived praise leadership by principals was found to mediate the relationship between turnover
intentions and organizational commitment among early childhood teachers.
Conclusions Even if early childhood teachers have turnover intentions, the effective display of praise leadership
by principals positively influences their organizational commitment. These findings highlight the importance of
continuous research on enhancing the praise leadership of educational institution principals.
Exploring the applicability of the Metaverse on English Curriculum for Generation MZ learners
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Insu , Yoo Ji Ho
Published: September 2023

Objectives The purposes of this study were to explore the applicability of the Metaverse on 2022 revised English
curriculum for generation MZ learners.
Methods For the objectives of the study, the 2022 revised curriculum draft, the English department revised curriculum,
the phased implementation plan for the full application of the 2025 high school credit system (Ministry
of Education, 2021.8. 22.) and the National Education Council under the direct control of the President(2021.9.8.)
were analyzed in the normative, structural, constitutional, technical, and ethical and social justice dimension,
based on the four-dimensional policy analysis model of Copper at al.
Results As a result of the analysis, the possibility of using metaverse in English classes for the MZ generation was
found in the normative dimension. Limitations in using metaverse in English classes were the absence of educational
metaverse platforms, lack of educational content available in metaverse, and cyber ethics and information
utilization gaps. Institutional and administrative support to tackle these issues were found in the structural and
technical dimension.
Conclusions Metaverse can contribute to improving the “English Communication Competence,” which is the overall
core competency of the 2022 revised English curriculum. Moreover, it has been confirmed that it enables
English learning tailored to the characteristics of MZ generation learners. The study suggests The Minstry of
Education, Korea Institute of Curriculum and Evaluation, and the Office of Education to give support and help in
developing educational metaverse platforms and contents, cyber ethics and Digital Literacy education as well as
in devising metaverse-mediated teaching and learning techniques for high school credit system and Digital
Literacy.
Pure non-Markovian evolutions
Authors: De Santis Dario
Published: September 2023

Non-Markovian dynamics are characterized by information backflows, where the evolving open quantum system retrieves part of the information previously lost in the environment. Hence, the very definition of non-Markovianity implies an initial time interval when the evolution is noisy, otherwise no backflow could take place. We identify two types of initial noise, where the first has the only effect of degrading the information content of the system, while the latter is essential for the appearance of non-Markovian phenomena. Therefore, all non-Markovian evolutions can be divided into two classes: noisy non-Markovian (NNM), showing both types of noise, and pure non-Markovian (PNM), implementing solely essential noise. We make this distinction through a timing analysis of fundamental non-Markovian features. First, we prove that all NNM dynamics can be simulated through a Markovian pre-processing of a PNM core. We quantify the gains in terms of information backflows and non-Markovianity measures provided by PNM evolutions. Similarly, we study how the entanglement breaking property behaves in this framework and we discuss a technique to activate correlation backflows. Finally, we show the applicability of our results through the study of several well-know dynamical models.
História das práticas da saúde e das doenças: epidemias e doenças
Authors: Martins Garcia Ana Karine , Rodrigues Gomes Elane Cristina , da Silva Suliman Sara , Pereira de Melo Júnior Jonas Clevison
Published: September 2023

A pandemia de Covid-19 possibilitou uma maior notoriedade e evidência aos trabalhos de diversos pesquisadores(as) da área da História da Saúde e das Doenças. Esse fato possibilitou a criação e expansão das atividades do Grupo de Estudo e Pesquisa da História das Práticas da Saúde e das Doenças (GEPHPSD/UFPA/CNPq). Nossas reuniões passaram a ser um espaço de diálogo e estudo sobre o passado, mas, sobretudo, de reflexão acerca das experiências e incertezas vivenciadas no presente que pairavam sobre o cotidiano da população brasileira e do mundo, marcando um momento de isolamento social, de negacionismo científico de governos extremistas e de milhares de mortes provocadas por uma doença que a princípio não havia uma vacina. A coletânea intitulada História das Práticas da Saúde e das Doenças, cujo nome é o mesmo do grupo de estudo mencionado, tem como objetivo central apresentar os resultados de pesquisas realizadas pelos integrantes do GEPHPSD, a partir de diferentes dossiês temáticos voltados tanto aos leitores acadêmicos como aos demais indivíduos e coletivos sociais. Buscamos, com este projeto, possibilitar que os conhecimentos advindos do campo da história da saúde e das doenças e de seus temas transversais alcancem um maior número de pessoas da sociedade brasileira. Este terceiro dossiê, intitulado Epidemias e doenças, tem como proposta apresentar diferentes estudos que dialoguem com a historiografia que trata das doenças e epidemias em atingiram a sociedade brasileira em diferentes épocas e lugares ao longo da história do Brasil.