bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Technology Characteristics and Literacy Among Families With Children With Asthma: Cross-Sectional Study
Authors: Kan Kristin , Morales Lu , Shah Avani , Simmons Emily , Barrera Leonardo , Massey Liana , List Greta , Gupta Ruchi S
Published: November 2023

Background

The use of digital technology in pediatric asthma management has emerged as a potential tool for improving asthma management. However, the use of digital tools has the potential to contribute to the inequitable delivery of asthma care because of existing social factors associated with asthma disparities. Our study focused on parents’ chosen language and sociodemographic factors that might shape the use of digital technology in asthma self-management.

Objective

This study aims to estimate and compare patient, family, and technology-related characteristics by parents’ chosen language (English or Spanish) and compare a digital literacy measure by sociodemographic factors.

Methods

Survey data were collected from July to December 2021 from parents of children with asthma who were seen by a Chicago pediatric health system pulmonary provider. Questions assessed patient and family characteristics, digital technology use, and digital literacy, measured using the validated eHealth Literacy Scale (eHEALS). Chi-square tests and multivariable logistic regression were used for comparisons, and Kruskal-Wallis tests were used for comparing median eHEALS scores by social characteristics.

Results

Of the 197 parents surveyed, 24.4% (n=49) of parents identified as a race categorized as other, 37.1% (n=67) as White, and 38.6% (n=75) as Black; 47.2% (n=93) identified as Hispanic/Latino/Latina. Additionally, 79.7% (n=157) of parents preferred English, and 20.3% (n=40) preferred Spanish. English-speaking parents were more likely to report having a data plan for their smartphone (117/157, 74.5%) or high-speed internet (138/157, 87.9%) compared to Spanish-speaking parents (smartphone: 23/40, 58%; P=.03; internet: 27/40, 68%; P=.002). Compared with Spanish-speaking parents, English-speaking parents were less likely to report having a lot or some concern about paying for internet (28/40, 70% vs 83/157, 52.9%; P=.046) or about data privacy (35/40, 88% vs 105/157, 67.5%; P=.01). Digital literacy scores differed significantly by race, income, education level, and language. In a multivariable model, language was not a significant factor for having high-speed internet service (P=.12) or concern about paying for internet at home (P=.60), but it was a significant factor for concerns about data privacy (P=.04).

Conclusions

The significant differences in technology-related characteristics suggest that digital connectivity, affordability, and data privacy may also be important factors in considering digital technology use in asthma care.
User-Centered Design of a Gamified Mental Health App for Adolescents in Sub-Saharan Africa: Multicycle Usability Testing Study
Authors: Pozuelo Julia R , Moffett Bianca D , Davis Meghan , Stein Alan , Cohen Halley , Craske Michelle G , Maritze Meriam , Makhubela Princess , Nabulumba Christine , Sikoti Doreen , Kahn Kathleen , Sodi Tholene ,   DoBAt & Ebikolwa Consortium, van Heerden Alastair , O’Mahen Heather A
Published: November 2023

Background

There is an urgent need for scalable psychological treatments to address adolescent depression in low-resource settings. Digital mental health interventions have many potential advantages, but few have been specifically designed for or rigorously evaluated with adolescents in sub-Saharan Africa.

Objective

This study had 2 main objectives. The first was to describe the user-centered development of a smartphone app that delivers behavioral activation (BA) to treat depression among adolescents in rural South Africa and Uganda. The second was to summarize the findings from multicycle usability testing.

Methods

An iterative user-centered agile design approach was used to co-design the app to ensure that it was engaging, culturally relevant, and usable for the target populations. An array of qualitative methods, including focus group discussions, in-depth individual interviews, participatory workshops, usability testing, and extensive expert consultation, was used to iteratively refine the app throughout each phase of development.

Results

A total of 160 adolescents from rural South Africa and Uganda were involved in the development process. The app was built to be consistent with the principles of BA and supported by brief weekly phone calls from peer mentors who would help users overcome barriers to engagement. Drawing on the findings of the formative work, we applied a narrative game format to develop the Kuamsha app. This approach taught the principles of BA using storytelling techniques and game design elements. The stories were developed collaboratively with adolescents from the study sites and included decision points that allowed users to shape the narrative, character personalization, in-app points, and notifications. Each story consists of 6 modules (“episodes”) played in sequential order, and each covers different BA skills. Between modules, users were encouraged to work on weekly activities and report on their progress and mood as they completed these activities. The results of the multicycle usability testing showed that the Kuamsha app was acceptable in terms of usability and engagement.

Conclusions

The Kuamsha app uniquely delivered BA for adolescent depression via an interactive narrative game format tailored to the South African and Ugandan contexts. Further studies are currently underway to examine the intervention’s feasibility, acceptability, and efficacy in reducing depressive symptoms.
A Picofarad Capacitance Meter Based on Phase-Sensitive Demodulation for Tomography Application
Authors: Alfanz Rocky , Hamzah Hamzah , Firmansyah Teguh , Saraswati Irma , Ahendyarti Ceri , Rohmadi Rohmadi , Muttakin Imamul
Published: November 2023

Electrical capacitance volume tomography (ECVT) is an imaging technique based on the object’s capacitance value. To provide a representative image of the object under study, the ECVT system requires a method that can measure the capacitance value in the order of picofarads (pF). This level of resolution poses a difficulty for typical commercial capacitance measuring devices, hence raising the need for a specialized method with dedicated signal conditioning circuitry. The capacitance meter based on phase-sensitive demodulation (PSD) is made to solve the aforementioned issue and it is then compared with the characteristics of a capacitance meter-based commercial Arduino setup. The designed PSD-based capacitance measuring device has 97.894% accuracy, precision of 0.704 pF, sensitivity of 0.1197 V/pF, linearity with a coefficient of determination 0.9983, and stability of 0.028 pF/min. In comparison, the capacitance meter based on Arduino has 97.943% accuracy, precision of 0.027 pF, linearity with a coefficient of determination 0.9999, and stability of 0.04 pF/min. Testing is done on an 8-electrode ECVT sensor using dielectric materials of air and water. The nearest electrode pair on the condition of air as the dielectric medium has a capacitance value of 2.62218 pF for PSD-based measuring devices and 3.4027 pF for Arduino-based measuring devices, while the pair of electrodes on the condition of water as a dielectric medium has a capacitance value 9.8229 pF for measuring device based on PSD and 9.1069 pF for Arduino-based measuring devices. The opposite and farthest electrode pair on the condition of air as a dielectric medium has a capacitance value of 0 pF for PSD-based measuring devices and 0,0798pF for Arduino-based measuring devices, while the pair of electrodes on the condition of water as a dielectric medium has a capacitance value of 4.652 pF for PSD-based measuring devices and 0.1224 pF for Arduino-based measuring devices.
Hedging in Newspaper Headlines Written by Indonesian and American Writers
Authors: Sa`adah Ma`rifatus , Hardjanto Tofan Dwi
Published: November 2023

Newspaper headlines contain the main and most important news articles in the newspaper. They are aimed to present news as accurately as possible. On the other hand, newspapers are also a company that aims to make profit from every news that is published. Thus, they have other interests besides conveying news as accurately as possible. One possible strategy to balance these two different interests is to use a hedging strategy. This research is an attempt to find out the forms and functions of hedging expressions used in headlines from two newspapers, The Jakarta Post and New York Times newspaper. The headlines that are used as the object of study are limited to the headlines containing news about the pandemic covid-19. This study also compares the forms and frequency of hedging expressions used in The Jakarta Post and New York Times. The data were quantitatively analyzed with a help of concordance software Wordsmith 4.0 (Scott, 2004). A qualitative analysis method was also conducted to classify the forms and functions of hedging expressions. A taxonomy proposed by Salager-Meyer (1997) was employed to analyze the forms of hedging expressions and Hyland (1996b) taxonomy was applied to identify the functions of hedging expressions serve in newspaper headlines. The results show that both groups of writers tend to employ hedging expressions in terms of the forms and functions in the similar way. Moreover, there was no significant difference in the use of hedging expressions by two groups of writers.
Financial Risk and Governance Nexus in Nepalese Cooperative Societies
Authors: Paudel Gyanendra Prasad
Published: November 2023

This study aims to investigate the relationships between credit default risk, leverage risk, liquidity risk, and investment risk and their connection to the governance system of Nepalese cooperative societies. The research hypothesis tries to explore that these financial risks are not significantly associated with the governance system of cooperatives. The findings reveal a significant connection between the governance system of cooperatives and credit default risk, leverage risk, and investment risk. However, liquidity risk does not demonstrate a substantial link with the governance system, suggesting the influence of additional factors. These results underscore the pivotal role of effective governance in mitigating financial risks within cooperative societies. Interestingly, the lack of a significant connection between liquidity risk and the governance system implies that other factors are at play in influencing liquidity risk. These insights provide valuable guidance for policymakers and cooperative management, facilitating the enhancement of governance and risk management strategies, and ultimately contributing to the sustainability of cooperative societies in Nepal. The evaluation involves a comprehensive analysis of financial risks and the governance system in Nepalese cooperative societies, utilizing data from a sample of 126 cooperative societies in Kathmandu.
E-Blood Banking System Using Cloud Computing
Authors: Kandukuri Sree Vagdevi
Published: November 2023

Abstract: Across the globe, there is an ever-increasing shortage of blood, which has led to many deaths. These losses are mainly due to the lack of a centralized blood donation system. Technologies have enhanced the efficiency and effectiveness of every aspect of the health industry, and information systems manage the distribution of blood through cloud computing. An automated system is needed to superintend the centers and provide information to interested parties. Research methodology involves a exploratory literature review and using aforesaid studies related to the ongoing situation to collect data. Our goal is to eliminate these problems through this website that satisfies all these requirements. The integrated framework includes a database for storing blood donation data in a centralized location for analysis. A database is used in this system to manage and store the data using HTML,PHP, and MySQL. In addition to educating the local community on the importance of blood donation, the website provides easy access to blood donation information, allowing hospitalsin India to store and distribute blood. As a conduit between health care systems and the public, the Arogini blood bank management system acts as a liaison. In a short period,the system will enable users to locate donors who havespecific blood groups, permit new donors to register, and help patients to request blood
Penyuluhan tentang Problematika dan Perlindungan Hukum Pekerja Migran Indonesia di Hongkong
Authors: Budiono Arief , Absori  , Bangsawan Moh Indra , Wardiono Kelik , Sukoco Bambang , Diarti Dewi Kusuma , Nanik Rumiati
Published: November 2023

Berangkat dari permasalahan perlu adanya perhatian serius dari pemerintah terkait jaminan perlindungan tenaga kerja Indonesia di luar negeri melalui penegakan hukum sehingga dapat menepis anggapan bahwa hukum dimanfaatkan oleh oknum tidak bertanggungjawab untuk membuat pola aktivitas perbudakan modern akibat lemahnya penegakan hukum. Pengabdian kepada masayarakat ini bertujuan untuk: 1). Mendeskripsikan perlindungan hukum pekerja migran Indonesia saat ini; dan 2). Mendeskripsikan upaya penyelesaian problem yang menimpa para pekerja migran Indonesia di luar negeri. Hasil pengabdian kepada masyarakat dengan mitra Pimpinan Cabang Istimewa ‘Aisyiyah Hong Kong menunjukan bahwa terdapat permasalahan hukum yang hingga saat ini tengah dihadapi oleh masyarakat antara lain permasalahan belum optimalnya penyelesaian konflik yang dialami oleh pekerja migran Indonesia di luar negeri. Sebagai upaya membantu masyarakat untuk menghadapi persoalan hukum tersebut, maka diselenggarakan pengabdian kepada Masyarakat yang dilakukan secara langsung sebagai wadah untuk menyiapkan pekerja migran Indonesia yang memiliki kesadaran diri dan kepedulian kepada isu-isu hukum dan keadilan sosial. Melalui Pengabdian hukum ini, para Pekerja Migran Indoensia menjadi paham terkait hak-hak dan metode penyelesaian hukumjika terjadi konflik.
 
Abstract
Counseling on Problems and Legal Protection of Indonesian Migrant Workers in Hong Kong.
Starting from the problem, there needs to be serious attention from the government regarding guaranteeing the protection of Indonesian workers abroad through law enforcement so that it can dispel the notion that the law is being used by unbalanced individuals to create a modern pattern of freezing activities due to weak law enforcement. This community service aims to: 1). Describe the current legal protection of Indonesian migrant workers; and 2). Describe efforts to resolve problems affecting Indonesian migrant workers abroad. The results of community service with partners from the Special Branch Leader of 'Aisyiyah Hong Kong show that there are legal problems that are currently being faced by the community, among other problems that have not yet optimally resolved the conflicts experienced by Indonesian migrant workers abroad. As an effort to help the community face these legal problems, community service is carried out directly as a forum for preparing Indonesian migrant workers who have self-awareness and concern for legal and social justice issues. Through this legal service, Indonesian migrant workers become aware of their rights and methods of legal resolution if a conflict occurs.
Development of augmented reality learning media based on assemblr studio web in ecosystem material
Authors: Nengsih Nengsih , Eka Anandita Eka Setiadi , Sunandar Ari
Published: November 2023

Augmented Reality displays realistic-looking 3D animations. Learning media utilizing Augmented Reality can assist students in comprehending Biology education, particularly ecosystem materials, with greater concreteness. This study reports the development of Augmented Reality learning media based on Assemblr Studio Web, known for its validity and positive response from students. The research employs the Research and Development (R&D) approach with a 3D modification development model derived from the 4D model developed by Thiagarajan. The Augmented Reality learning media based on Assemblr Studio Web received highly valid assessments from subject matter experts (85.18%), media experts (90%), and language experts (80.83%). In a small-scale trial involving 27 students, a response rate of 78.51% (positive) was recorded, while in a large-scale trial with 63 students, the response rate was 76.4% (positive). It is concluded that the developed Augmented Reality learning media based on Assemblr Studio Web is highly suitable for use in the learning process and has received positive feedback from students.
Inhalation Anesthetics for Postoperative Nausea and Vomiting in General Anesthesia Patients
Authors: Saifuddin Ircham , . Destiana , Aziz Muhammad Abdul , Palestin Bondan
Published: November 2023

Background: Postoperative nausea and vomiting is an anesthetic complication which is related to various factors. Patients who experience postoperative nausea and vomiting have worse quality of recovery which causes delay in patient discharge from the hospital which will increase the cost of care. Objective: To knowing the effect of inhalation anesthetics on postoperative nausea and vomiting in general anesthesia patients at Dr Soedirman Hospital Kebumen. Method: The study is a quasi-experimental quantitative study with a pre-test-post-test design with a control group design. The population of the study were all patients undergoing general anesthesia at Dr Soedirman Hospital Kebumen. The study was conducted in September - October 2022 with a sample of 56 respondents for each group which was determined using a purposive sampling technique. Data analysis using the Wilcoxon test. Result: Results of analysis of the effect of inhalational anesthesia on postoperative nausea and vomiting in general anesthesia patients at Dr Soedirman Hospital Kebumenp (sig) 0.000. Conclusion: There is an effect of inhalation anesthetics on postoperative nausea and vomiting in general anesthesia patients
Randomized two way crossover open label study to compare the bioequivalence of LOSARDIL 100 TM (Drug International Ltd, Bangladesh) and COZAAR TM (Merck Sharp & Dhome Ltd, UK) in Bangladeshi normal male volunteers
Authors: Sarker Uttam Kumar , Farhana Fatiha , Islam Atikul , Misbahuddin Mir , Islam Md. Rabiul
Published: November 2023

Objectives: A crossover-randomized bioequivalence study of two oral formulations of losartan (100 mg) tablets was carried out in 16 healthy male Bangladeshi volunteers. The test and reference formulations were LOSARDIL 100™ (Drug International Ltd, Bangladesh) and COZAAR™ (Merck Sharp & Dohme Ltd, UK), respectively.

Methods: Each tablet was administered with 150 mL of water to subjects after whole night fasting condition on two therapy days distinct by 1 week washout period. After administration, blood samples were accumulated periodically for 24 hours. The plasma concentrations of losartan were evaluated using a validated HPLC method. The pharmacokinetic parameters Cmax, Tmax, AUC0→24h, t1/2, and Kel were determined.

Results: The mean (± SD) AUC0→24h for losartan of test drug LOSARDIL 100TM for 16 volunteers was 3310 ± 1165 ng.hr/mL whereas it was 3545 ± 1251 ng.hr/mL for losartan of COZAARTM . The relative bioavailability (LOSARDIL 100TM/COZAARTM ratio) was 93%. The Cmax, tmax, half-life of elimination (t1/2) and the rate of elimination (Kel) of losartan of test drug were 1855 ± 675 ng/mL, 0.77 ± 0.39 hours, 4.69 ± 1.17 hour and 0.15 ± 0.04 respectively. The Cmax, tmax, half-life of elimination (t1/2) and the rate of elimination (Kel) of losartan of reference drug were 2254 ± 944 ng/mL, 0.87 ± 0.29 hours, 4.13 ± 1.41  hour and 0.20 ± 0.04 respectively.  

Conclusion: Depend on the statistical interpretation the 90% CI for the test and reference drugs were observed within the acceptance range of 80-125%. In conjecture, LOSARDIL 100™ is bioequivalent to COZAAR ™ in terms of absorption.
The Effect of Gaze Stability Exercise Intervention on Increasing Dynamic Balance in the Elderly
Authors: Lina Ratu Karel , Ningrum Olivia Filziah , Sariana Erna , Manurung Santa , . Wartonah
Published: November 2023

Background: Physiological changes from decreased muscle strength, posture change, somatosensory system (visual, vestibular, proprioception) causes balance disorders in elderly. Gaze stability exercise is a proper exercise since it is based on pathophysiology of elderly imbalance caused by aging of sensory system and skeletal muscle. Objective: to find out the effect of Gaze Stability Exercise Intervention on increasing dynamic balance in elderly. Method: a pre-experimental with one group pre-posttest design. There were 11 elderly as samples selected with purposive sampling technique. Intervention was done twice a week for four weeks with duration of 60 minutes. Dynamic balance measurement used Time Up and Go Test (TUGT). Data analysis used was paired- t test. Result: The average time up and go test before intervention was 17.82 and after invention was 13.82.the result of before and after statistical test showed p value of 0.000 (p<0.05). Conclusion: There is an effect of Gaze Stability Exercise Intervention on increasing dynamic balance in elderly
Synthesis and Anti-Microbial Activity of 3-Hydrazinyl-7- Ethylquinoxaline-2(1h)-Thiol Derivatives
Authors: Teli Sangappa , Teli Dharyappa
Published: November 2023

There are various pharmaceutical applications for quinoxaline derivatives. Benzoheterocycles, 6-methylequinoxalin-2,3-diones, and 3-Hydrazinyle are quinoxaline derivatives. 7-Methoxyquinoxaline-2(1H)-thiol Derivatives TLC, Melting Point, FT-IR, and 1HNMR are used to describe quinoxaline compounds such as SG-IA, SG-IB, SG-IC, SG-ID, SG-IE, and SG-IF. Biological activity data showed that SG-IC and SG-IB were moderately active, whereas SG-IA, SG-ID, SG-IE, and SG-IF had average activity when compared to the standard. The test compounds were discovered to be more sensitive to Gram-positive bacteria such as Staphylococcus aureus and Escherichia coli (Gram-negative bacteria).
Formulation and Evaluation of Nicorandil Floating Tablets Using Natural Polymers
Authors: Srivastava Anoop Kumar , Rajput Dharmedra Singh , Gupta Naveen , K Sharma Neeraj
Published: November 2023

The present work described the pre-formulation and formulation development that led to the production of Nicorandil (NDL) floating tablets by direct compression of a homogeneous powder blend/ granules. In order to achieve the drug (NDL) release up to 24 hrs, rafting approach was selected. Studies have been carried out on rafting method by the use of natural polymers (sodium alginate, xanthan gum and guar gum) alone and their combination to get maximum rafting properties with superior drug release retarding activity. The results obtained in the rafting approach indicated that the polymer combination showed significant influence on rafting properties with maximum drug release retarding ability than individual polymers. In addition, the polymer combination of xanthan gum and guar gum resulted with maximum drug release retarding ability with poor rafting properties, whereas, the polymer combination of sodium alginate and guar gum resulted with predictable release behaviour (i.e. slightly lower retarding ability than the combination of xanthan gum and guar gum) with maximum rafting properties.  As such the floating tablets prepared with rafting approach were recommended for oral controlled delivery of NDL.
Involvement of iNKT Cells In Bronchial Asthma
Authors: Kandari Swarnima , . Ratnakar , Chandola Abhishek
Published: November 2023

Background: Bronchial asthma is a prevalent inflammatory disease characterized by infiltration with eosinophils, lymphocytes, and mast cells in the airway leading to airway hypersensitivity and increased mucus secretion. T helper (Th) 2-based immune responses drive the inflammatory process. Numerous mechanisms are being studied to understand the progression of allergen induce asthma which subsequently led to the identification of a new population of T cells called the iNKT cells which showed promising results when experimented on murine models.  iNKT cells are potent immune modulators involved in a variety of immunoregulations. This potency is the result of their ability to produce prime Th2 cytokines. The recognition of lipid antigens is required for the activation of iNKT cells. When an inflammation occurs due to Th2 cells and ozone, endogenous glycolipids become modified. This causes the activation of various subsets of iNKT cells and initiates airway hyperactivity. Infrequent human studies depict that the number of iNKT cells in BAL fluid ranges from 1 % of lung lymphocytes to 14 % which is a sign of dynamic fluctuation in the number of iNKT cells.

Methods: Selective literature review including primary and secondary sources of literature. Eg. Cochrane database, NCBI, MEDLINE database.
An Overview on Microemulsion as a Topical Drug Delivry System
Authors: Nishigandha Naikawadi , Prakash Jadhav , Avinash Bhagwat , Atish Velhal , Vivek Kumar Redasani , Mayuri More
Published: November 2023

Due to their extended shelf life, enhanced drug solubilization, and simplicity in preparation and administration, microemulsions are among the greatest possibilities for new drug delivery systems. Microemulsions are liquid mixtures of amphiphile, water, and oil that are thermodynamically stable and optically isotropic. They have become cutting-edge drug delivery systems that enable controlled or sustained release for parenteral, ophthalmic, percutaneous, topical, and transdermal medication administration.Because of their low viscosity, transparency, and, more precisely, their thermodynamic stability, microemulsions may be easily distinguished from regular emulsions. Microemulsions have a wide range of uses and applications, including in the pharmaceutical, agrochemical, cutting oil, biotechnology, food, and cosmetic industries as well as in analytical applications and environmental detoxification. This review paper's main goal is to talk about using microemulsions as a medicine delivery mechanism with other potential uses.
A Comprehensive Review on Transdermal Delivery of Nanosponges
Authors: Poonam Raut , Prakash Jadhav , Priyanka Sangar , Vivekkumar Redasani , Nikita Bhosale , Varda Joshi
Published: November 2023

The field of innovative medication delivery has greatly benefited from nanotechnology and miniaturisation, which have also transformed the potential in the current healthcare industry. The design of nano-scale drug carriers using various nanotechnology-based approaches for the delivery of lipophilic drug molecules is the current trend in novel drug delivery-based research. Nanotechnology and miniaturisation, which have also changed the possibilities in the contemporary healthcare business, have tremendously helped the field of inventive medicine distribution. Targeting medication distribution in a regulated manner is made possible in large part by NSs. The use of NSs, its preparation, and assessment have all been covered in this review paper. The healthcare industry is seeing encouraging results from a variety of nanosponges formulations, including parenteral, topical, oral, and inhalation, which offer enormous promise for future development and study.
Role of Jalokaavacharana in the Management of Varicose Veins (Sirajgranthi)- A Case Study
Authors: Kazi Wasim , Patel Jigna , Sharma Varsha , Panchal Sonal
Published: November 2023

When a vein becomes dilated, elongated and tortuous, the veins is said varicose. The common sight of varicosity are superficial venous system of lower limb effecting either long or short  saphenous veins, oesophageal varices, varicosity of haemorrhoidal veins, varicosity of spermatic veins. Generally varicose veins are compared with sirajgranthi according to Ayurveda. Acharya Sushruta had described various types of granthi and its various treatment modalities among them jalaukaavacharana is one of them. Sushruta had given special chapter related to jalauka in which he had described the types, nomenclature, specific qualities of each types of jalauka, their method to apply and detach and how to do vamana of jalauka. Acharya charak also described jalauka as best amongst all anushashtras. Jalaukapossesessheet guna in nature and on the basis of sign and symptoms varicose veins can be correlated with sirajgranthi. In this case study a 36- year old woman of bilateral varicose veins was treated successfully and found symptomatic relief.
Inspections – Key Role in Quality of Medicines
Authors: Shah Manan , Shah Vishal
Published: November 2023

Global patients depend on medications for their specific purposes. These drugs are manufactured both domestically and internationally. Regardless of where they are manufactured, the Food and Drug Administration (FDA) plays a pivotal role in the United States, regulating drugs, biologics, and devices by not only scrutinizing each marketing holder's application but also guaranteeing that the product's manufacturer complies with current good manufacturing practices (cGMP). This ensures that the product's quality is consistent and is manufactured securely for its intended use.
“Foi bacana o que a toupeira fez?”: conversando com crianças nas rodas de história na educação infantil
Authors: Souza Nascimento Bárbhara Elyzabeth , Perrusi Brandão Ana Carolina , Magalhães Fabiana Andrade Santana
Published: November 2023

O estudo discute a leitura de histórias e conversa de uma professora com seu grupo de crianças de 5-6 anos. Os diálogos foram videogravados e transcritos, sendo analisados qualitativamente os trechos em que os pequenos foram convidados a opinar, justificar e confrontar ideias a partir das histórias lidas. Os livros de literatura selecionados pela docente atendiam à critérios estéticos e traziam temas interessantes para conversar. Entretanto, em quatro das seis rodas de história observadas, a conversa parecia ser guiada, de forma doutrinária, em direção ao ensino de certos valores morais. Os dados apontam a necessidade de explorar outras possibilidades de mediação que promovam o pensamento das crianças e sua autonomia para se posicionar frente às questões controversas suscitadas pelas histórias lidas na roda.
Editorial
Authors: Wassem Joyce
Published: November 2023

É com satisfação que apresentamos o volume 11, ano 2020, da revista Educação em Perspectiva. A revista completa, assim, seu segundo ano de experiência com o modelo de Publicação Contínua (Rolling Pass).
Desejamos aos leitores e leitoras que os textos suscitem importantes reflexões e ações em suas práticas cotidianas.
Penggunaan Media Gambar untuk Meningkatkan Semangat Belajar IPA pada Siswa Sekolah Dasar
Authors: Tuti Tuti Painaah
Published: November 2023

Penelitian ini bertujuan untuk mengetahui semangat belajar IPA siswa kelas V SDN 78/IX Nyogan Tahun Pelajaran 2016/2017 melalui penggunaan media gambar. Penelitian ini merupakan penelitian tindakan kelas (PTK), dengan menganalisis secara deskriptif. Penelitian ini terdiri dari dua siklus. Pengambilan data dalam penelitian ini dilakukan pada bulan September sampai bulan Oktober 2016. Subjek dalam penelitian ini adalah siswa kelas V yang berjumlah 33 orang siswa terdiri dari 17 orang laki-laki dan 16 orang perempuan. Berdasarkan analisis data yang diperoleh peneliti, hasil belajar siswa sebelum PTK yaitu 72.1. Setelah PTK pada siklus I pertemuan 1 hasil belajar siswa adalah 81.8 dan pada pertemuan 2 sebesar 82.7. Pada siklus II pertemuan 3 hasil belajar siswa 85.2 dan pada pertemuan 4 sebesar 86.9. Berdasarkan hasil penelitian menunjukkan bahwa penggunaan media gambar dapat meningkatkan hasil belajar IPA pada siswa kelas V SDN /IX Nyogan Tahun Pelajaran 2016/2017.
PENGARUH BAURAN PEMASARAN TERHADAP PERILAKU KONSUMEN PADA PEMBELIAN SAYUR DI PASAR MODERN JUMBO MART DELIMA DI KECAMATAN TAMPAN KOTA PEKANBARU
Authors: KHASANAH USWATUN , Kusumawaty Yeni , Eliza Eliza
Published: November 2023

Pasar modern merupakan pasar yang yang dikelola menggunakan manajemen yang lebih modern, dalam pengelolaan pasar modern dibutuhkan bauran pemasaran yang baik untuk menyampaikan informasi secara luas, memperkenalkan suatu produk barang dan jasa, merangsang konsumen untuk membeli bahkan menciptakan preferensi pribadi terhadap image suatu produk. Kecamatan Tampan memiliki 140 pasar modern salah satunya adalah pasar Modern Jumbo Mart Delima yang menjual berbagai kebutuhan masyarakat salah satunya sayur-sayuran dengan jenis terlengkap. Tujuan Penelitian ini adalah 1) Mengetahui persepsi konsumen terhadap baurran pemasaran 2) Menganalisis bauran pemasaran produk, harga, tempat, pelayanan dan promosi terhadap perilaku konsumen. Penelitian ini  dilaksanakan di Pasar Modern Jumbo Mart Delima Di Kecamatan Tampan Kota Pekanbaru. Penentuan responden dilakukan secara purposive sampling dengan kriteria yaitu konsumen sudah berusia 17 tahun dan sudah berbelanja minimal dua kali. Analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif dan analisis regresi linier berganda. Hasil penelitian ini adalah produk,harga,tempat dan pelayanan berpengaruh signifikan terhadap perilaku konsumen, sedangkan pelayanan tidak berpengaruh signifikan.
STUDY DESKRIPTIF KECERDASAN EMOSIONAL PENGHAFAL AL-QURAN KELAS 8 MTS PERSIS TAROGONG
Authors: Nuraeni Imas Hikmah , Sobari Teti , Supriatna Ecep
Published: November 2023

In the learning process at school, we often see students who are less able to process their emotions so that it affects their learning outcomes. Therefore, intellectual intelligence is not the only success of a child but because there are others who influence it. Including the emotional turmoil that is happening in the development of adolescent students. In the development of students, it is not only intellectual intelligence that must be improved but emotional intelligence must also be developed because adolescents must be able to adapt and manage emotions to changes that occur. In this study, researchers describe emotional intelligence. The purpose of this study was to describe the emotional intelligence of 8th grade students at MTs Persis Tarogong Garut. The method used in this research is descriptive quantitative. The results of this study indicate that the category of emotional intelligence of 8th grade students of MTs Persis Tarogong is in the medium category.
PENGEMBANGAN MEDIA VIDEO ANIMASI MOTIVASI BELAJAR BERBASIS ANIMAKER BAGI SISWA KELAS VII DI SMP NEGERI 9 CIMAHI
Authors: Mardhiyyah Rahmah Winnit , Rohaeti Euis Eti , Septian Muhammad Rezza
Published: November 2023

Motivation has a very big influence in learning activities that can support students in achieving good learning outcomes, if students do not have learning motivation, students will not be optimal in carrying out learning activities. This description makes it important to understand learning motivation for students in general and in particular for class VII students at SMPN 9 Cimahi. This study aims to produce animated video media products to provide a concrete understanding of increasing learning motivation. The research method used is research & development (R&D) with development procedures referring to Borg & Gall which are simplified by the Puslitjaknov Team into five stages. The subjects in this study included 1 material expert, 2 media experts, 1 school counselor practitioner, 10 students, and 34 students. The data obtained in this study are quantitative data that refers to the acceptability criteria of the material and the criteria of learning media which are analyzed by descriptive statistics, as well as qualitative data in the form of comments and suggestions on the product. The results obtained based on product validation from material experts reached 96%, media experts at 100%, and school counselor practitioners 96%. Meanwhile, 87% of students' responses were limited and 91% of students' responses were wider in scope. Based on the results of the study, this research can produce a product in the form of an animated video which is empirically proven to be used as a medium for guidance and counseling services.
Investigating the factors of selecting audit clients: Evidence from an emerging market
Authors: Hegazy Karim , Chong H. Gin , Kamareldawla Noha Mahmoud
Published: November 2023

This study investigates the insights and criteria audit partners use to select prospective clients in an emerging market. We use questionnaires to solicit responses from a sample of auditors at the partner/manager level in Big and non-Big 4 audit firms with international affiliations in an emerging economy. Descriptive statistical tools including the chi-square test and multiple logistic regression analysis are used for the analysis. This study finds that auditor reputation enhancement and corporate governance effectiveness are significantly associated with the acceptance of listed companies and that the higher financial reporting quality of listed companies and the need to promote audit and assurance services are significant factors affecting such decisions. Audit firms tend to select parents or subsidiaries because of the expected effective audits and reduced misstatement and litigation risks and audit firm industry expertise is needed to mitigate expected client risks to significantly affect the selection of clients with prior-year audit qualifications. Fraud is significantly associated with the selection of clients with prior violations reported by government monitoring bodies. This study is among the few empirical studies in emerging economies that provide insights from practicing auditors on a set of comprehensive attributes that affect the selection of audit clients. The findings have implications for audit partners and firms, auditees, and the audit profession in selecting clients that fit the firm’s and profession’s vision of audit branding and reputation
Quantitative evaluation of mantle flow traction on overlying tectonic plate: Linear versus power-law mantle rheology
Authors: Cui Fengyuan , Li Zhong-Hai , Fu Hui-Ying
Published: November 2023

The sub-plate mantle flow traction has been considered as a major
driving force for plate motion; however, the force acting on the
overlying plate is difficult to be well constrained. One reason lies in
the variable rheological flow laws of mantle rocks, e.g. linear versus
power-law rheology, applied in previous studies. Here, systematic
numerical models are conducted to evaluate the mantle flow traction
under variable rheological, geometrical and kinematic conditions. The
results indicate that mantle flow traction with power-law rheology is
much lower than that with linear rheology under the same mantle/plate
velocity contrast. In addition, the existence of lithospheric root in
the overlying plate enhances the mantle flow traction. In a regime with
reasonable parameters, the mantle flow traction with power-law rheology
is comparable to the ridge push on the order of 1012 N/m, whereas that
with linear rheology is comparable to the slab pull of 1013 N/m.
Sustainable investing in protected areas and biodiversity: key enabling conditions in policy, law, and institutions
Authors: Lausche Barbara
Published: November 2023

This publication provides initial guidance to countries on key enabling tools for attracting public and private sector investments in conservation and how to navigate the process. It builds on a series of recent ELC protected areas and biodiversity projects, prompted by emerging investor interest in the sustainability of their investments and responding to the growing funding gap between what is needed and what is available in traditional financial sources (grants, philanthropy, national budgets and loans) to effectively address the planet’s growing environmental crises - accelerating biodiversity loss, climate impacts affecting the Earth and society, and expanding land, marine and ecosystem degradation.
Consumption of fruits of Dimorphandra jorgei M.F.Silva by Tapirus terrestris (Linnaeus, 1758) in a Remnant of Atlantic Forest in Southeast Brazil
Authors: Srbek-Araujo Ana Carolina
Published: November 2023

The Fabaceae family holds great ecological and economic importance. Some species contribute to increased nitrogen levels in the soil (association with mycorrhizae), benefiting the natural regeneration process. Other species have high therapeutic value, while another can be used for ornamentation and urbanization. This study reports the presence of seeds from a tree species in the Fabaceae family, Dimorphandra jorgei M.F.Silva, in the fecal sample of South American tapir, Tapirus terrestris (Linnaeus, 1758), in a remnant of the Atlantic Forest in Southeastern Brazil. The fecal sample was found on an unpaved road, between the forest edge and an area undergoing reforestation with native species. Our record corroborates that D. jorgei can be an important supplementary food item in the tapir’s diet in the region, with its consumption linked to dry periods. The fruits of D. jorgei are not morphologically attractive to vertebrate fauna in general, highlighting the importance of tapirs in the dispersal of this and other species with similar fruits. It is also emphasized that seed dispersal contributes to the maintenance and regeneration of vegetation, serving as an Ecosystem Service of Support.
Impacto de los conocimientos previos de álgebra y aritmética en el aprendizaje de funciones de cálculo diferencial
Authors: Rojas Maldonado Erick Radaí
Published: November 2023

El cálculo diferencial es una de las áreas de las matemáticas que presenta mayor complejidad, de ahí que, en muchos casos, constituya un verdadero reto para los estudiantes. Una de las razones por las que esto ocurre se debe a que para abordar el cálculo diferencial es necesario tener conocimientos sólidos en áreas previas de la matemática, como lo son el álgebra y la aritmética. En este sentido, el objetivo de esta investigación es analizar el impacto de los conocimientos previos del álgebra y la aritmética en el aprendizaje de funciones en el cálculo diferencial. Para ello, se empleó un paradigma cuantitativo, por medio de un estudio no experimental y exploratorio, con una muestra de 27 estudiantes. Asimismo, se aplicó un análisis de correlación que permite concluir que la calificación de conocimientos previos está positivamente relacionada con la calificación de funciones; además, no se presentó una diferencia significativa en la calificación de funciones y el sexo, y tampoco la edad es un factor importante para predecir el desempeño en funciones.
Dynamic Response of Layered Media to Impact Loading (on the Example of Highways)
Authors: Tiraturyan A. N. , Vorobev A. V.
Published: November 2023

Introduction. The main way to assess the load-bearing capacity of road structures (which are layered media consisting of materials of different stiffness) is through impact testing. The analysis of the results of these tests is reduced to the consideration of only peak values of vertical displacements without taking into account the change of these parameters in the frequency and time range. At the same time, it is the study of amplitude-frequency characteristics of displacements that can allow solving a number of urgent problems related, for example, to bringing the actual values of vertical displacements to the values under the design modes of operation of the structure.

The purpose of the study is to analyze the dynamic response of layered media (road structures) of automobile roads to impact loading, aimed at bringing the actual parameters of the dynamic response to the design values regulated by the requirements of domestic regulatory documents on road design.

Materials and Methods. Modern shock loading facilities allow to reproduce the load with a pulse time of 0.03 s, while the design values of elastic moduli are calculated for 0.1 s. To overcome this contradiction, the authors realized an exact solution of the dynamic Lame equation for a multilayered half-space and constructed a series of amplitude-frequency characteristics of displacements, from the processing of which a simplified functional dependence was derived.

Results. The methodology of construction of amplitude-frequency characteristics of displacements on the surface of road pavement under impact impact has been developed, which finds its practical application. On the basis of the exact solution of the dynamic Lame equation by means of statistical processing, a simplified regression dependence for vertical displacements is established. An example of calculation of the elastic moduli of the road structure layers taking into account their reduction depending on the time of load application is presented.

Discussion and Conclusion. Within the framework of the study, for the first time, a methodology for bringing the actual values of vertical displacements to the values under the design modes of operation of a road structure, based entirely on the computational analysis of its dynamic VAT, in particular, the amplitude-frequency characteristic of deformation under unsteady impact, has been obtained. The developed approach is able to significantly increase the reliability of diagnostics of highway condition, as well as to ensure the unity of measurements and results obtained during the design and diagnostics of roads.
Life cycle management of the ventilation system of a construction object
Authors: Samarskaya N. S.
Published: November 2023

Introduction. In the article, the author considers a mechanical ventilation system as a complex technical system that can be effectively controlled based on a model of its life cycle. Like any engineering system (or product, product, project), a ventilation system has its own life cycle, consisting of a set of successive stages. Each stage is characterized by its own types of work and final results that require management decisions.

Materials and Methods. The paper uses the method of analyzing the life cycle of complex technical systems, methods of collecting and processing statistical data, as well as methods of systematic and comparative analysis, generalization of scientific and practical results.

Results. In the course of the conducted research, the author applied the "life cycle management" approach to ventilation systems and achieved the goal of developing a model of their life cycle, which includes all stages of system development from conception to disposal. Possible ways of managing the life cycle of ventilation systems from the perspective of continuous interconnection of processes are determined.

Discussion and Conclusion. Effective life cycle management of a mechanical ventilation system can be implemented through the development of a software product capable of modeling processes and system elements even at the first stages of the life cycle. The software product should eliminate the existing problem of inconsistencies at different stages of work, store information about the object and provide access to it for each participant in the process. Solving the problem of creating a software product will ensure effective management of the entire life cycle of the ventilation system, reduce labor costs and inconsistencies and ensure compliance with modern requirements for operational reliability and energy efficiency of a vital engineering system.