bluuebunny/crossref_metadata_2025 huggingface dataset:
Sagrado ou profano?
Authors: Silva Giselle da Silva , Oliveira Francisco Pereira de , Silva Jair Francisco Cecim da
Published: February 2023

Este ensaio fotográfico, que está baseado na antropologia visual, narra a Festa de Todos os Santos, manifestação cultural- religiosa tradicional, que acontece na comunidade quilombola de Jurussaca, Tracuateua-PA. Essa Festa surgiu devido a uma promessa feita por um morador da comunidade: com o temor de que os homens da comunidade fossem para a guerra Seu Bibiano prometeu, caso não fossem, faria uma festa em homenagem a Todos os Santos, festa essa que acontece até os dias atuais (2014).
Generalized Tetanus in A Patient with Infected Sutured Wound: A Case Report
Authors: Tejaya Novi , Ramli Marina Musyawwirina Desiprimayanti Ruslan
Published: February 2023

Highlight:

Tetanus in patients with infected sutured wound.
Complications of death in generalized tetanus.
The importance of education about tetanus.

 
ABSTRACT
Introduction: Tetanus is a disease caused by Clostridium tetani, which produces an exotoxin. Tetanus can rapidly progress into life-threatening muscle spasms accompanied by respiratory insufficiency with or without autonomic dysfunction. Case: A 43-year-old male patient was referred from the public health center to Tora Belo Hospital with mouth stiffness and difficulty swallowing food. He also had stiffness and pain in the neck, abdomen, and lower back. Seven days prior, the patient received lacerations on his right forearm caused by a machete. The patient’s wound had been stitched up without an anti-tetanus injection at the public health center. The symptoms worsened on the second day of admission, and the patient died from respiratory failure. Conclusion: It is very important to enhance public awareness that tetanus is a preventable disease, with proper vaccination and sanitization potentially lowering mortality and morbidity.
Treatment of Wide-Neck Intracranial Aneurysm: Current Concepts and Endovascular Approach
Authors: Kurniawan Ricky Gusanto , Prasetyo Bambang Tri , Rilianto Beny , Windiani Pratiwi Raissa , Gotama Kelvin Theandro , Arham Abrar
Published: February 2023

Highlight:

Endovascular treatment is recommended for aneurysms
Wide-neck aneurysm is difficult to treat with endovascular approach.
Stent-assisted coiling and flow diverter are choices for wide-neck aneurysms

 
ABSTRACT
A wide-neck aneurysm, described as an aneurysm with a neck of 4 mm or a dome-to-neck ratio of <2, requires more advanced endovascular treatment than a narrow-neck aneurysm. Stent-assisted coiling (SAC) was the sole endovascular approach for wide-neck cerebral aneurysms, which were difficult to treat surgically or by embolization. More advanced endovascular approaches have since been developed in recent years, namely the flow diverter (FD) as an endovascular treatment for wide-neck cerebral aneurysms with an endoluminal reconstruction approach. Both techniques have advantages and disadvantages that must be studied further to develop a wide-neck cerebral aneurysm therapy. Therefore, based on the current literature, this article intends to review the differences in the efficacy and complications of SAC and FD for wide-neck aneurysm therapy.
PREDICTOR OF ANEMIA AMONG PEOPLE LIVING WITH HIV TAKING TENOFOVIR+LAMIVUDINE+EFAVIRENZ THERAPY IN JAYAPURA, PAPUA
Authors: Adiningsih Setyo , Kridaningsih Tri Nury , Widiyanti Mirna Widiyanti , Wahyuni Tri
Published: February 2023

Background: The most common hematological abnormality among people infected with Human Immunodeficiency Virus (HIV) is anemia. This is also related to high mortality risk among patients receiving Antiretroviral Therapy (ART). Purpose: This study aimed to identify predictorsf anemia among HIV patients taking ART using a regimen of the single-tablet drug contain tenofovir, lamivudine, and efavirenz in Jayapura, Papua. Methods: This was a cross-sectional study conducted at Jayapura regional hospital from June to September 2017. A total of 80 HIV patients were eligible for analysis. Data collection was conducted through an interview, medical record, measurement, and laboratory assay. The significance of differences among categorical variables was analyzed using Fisher’s exact test. The variables with p < 0.25 were then analyzed using binary logistic regression to determine predictors associated with anemia. A threshold of p < 0.05 indicates statistical significance. Results: This study showed that Body Mass Index (BMI) <18.50 (p = 0.01; OR = 5.63; 95% CI = 1.43 < OR < 22.19), length onRT ≤12 months (p = 0.00; OR = 4.90; 95% CI = 1.65 < OR < 14.53), and Cluster of Differentiation 4 (CD4+) percentage out of normal (p = 0.02; OR = 0.19; 95% CI = 0.05 < OR <0.77) had a significant association with anemia. Conclusion: BMI, length on ART, and CD4+ percentage were predictors of anemia among HIV patients taking antiretroviral therapy contain tenofovir, lamivudine, efavirenz regimen in Jayapura.
BARRIER PERCEPTION FACTORS AFFECTING THE ACCEPTANCE OF THE COVID-19 VACCINE IN SALATIGA CITY
Authors: Ma'rifati Lu'luil , Udijono Ari , Kusariana Nissa
Published: February 2023

Background: In Salatiga City, COVID-19 immunization still needs to meet the 70% vaccination target needed to generate herd immunity. Vaccine skepticism and injection phobia can be barriers. A study of community barriers to COVID-19 vaccination and vaccine uptake is needed. Purpose: This study aimed to analyze barriers affecting the acceptance of the COVID-19 vaccine in Salatiga City. Methods: The study collected data from 323 Salatiga City people. Fear of pain, doubts about the COVID-19 vaccine, perception of fear of AEFI (Adverse Events Following Immunization), perception of accessibility of the COVID-19 vaccine, and the perception of information about the COVID-19 vaccine were independent variables in this study. Acceptance of COVID-19 vaccination is dependent. Data analysis using Chi-Square with 0.05 significance. Results: The results of this study found a relationship between fear of pain (p-value = 0.00), doubt about the COVID-19 vaccine (p-value = 0.00), perception of fear of AEFI (p-value = 0.00), perception of accessibility of COVID-19 vaccine (p-value = 0.00), and perception of information about COVID-19 vaccine (p-value = 0.00) and acceptance of the COVID-19 vaccine by Salatiga City residents. Conclusion: Perceived COVID-19 vaccination barriers affected vaccine acceptance. Acceptance of COVID-19 vaccination in Salatiga City is related to fear of pain, doubt about the COVID-19 vaccine, perception of fear of AEFI, perception of accessibility of the COVID-19 vaccine, and perception of information about the COVID-19 vaccine. Salatiga City's COVID-19 education efforts should focus on vaccine safety and side effects in collaboration with health cadres and cross-sector collaboration.
IDENTIFYING MENTAL HEALTH FACTORS OF CANCER PATIENTS IN HOSPITAL X
Authors: Ruliyandari Rochana , Solikhah Solikhah , Rahmadhani Wulan , Nuraisyah Fatma
Published: February 2023

Background: Physical health of people living with cancer causes mental health disorders and unknowingly affects the overall quality of patients’ life. As many as 34.40% of cancer patients in Indonesia experience depression due to anxiety and fear. Objective: Therefore, this study was conducted to determine the mental health of cancer patients in the hospital so that the relationship between the mental health of cancer patients and other factors, such as the characteristics of the respondents, family support, and spirituality, is known. Methods: The type of research for this study is quantitative with a cross-sectional design using the Pearson Chi-Square analysis. There were 96 respondents in this study who were cancer patients from Hospital X. The independent variables used were the respondent’s demographic characteristics (age, gender, occupation, and education), family support, and spirituality, with the dependent variable being mental health (stress and depression). Results: The results of the study showed that cancer patients had the latest elementary school education (40.60%), status not working (61.50%), female (66.70%), early elderly (35.40%), 70.80% received moderate family support, 76% had moderate spirituality, 51% experienced moderate stress, and 57.30% had depression. The characteristics of respondents in this study, namely gender, education, occupation, and spiritual factors, were not associated with mental health in cancer patients. Conclusion: The results showed that age and family support were factors associated with the mental health of cancer patients, while other demographic characteristics (gender, occupation, and education) also spiritual factors were not associated with the mental health of the cancer patients.
Targeting the interactions between lymphocytes and liver cancer stem cells in combination with immunotherapy is a promising therapeutic strategy
Authors: Chen Wo-Ming , Zhang Xiao-Ping , Yan Yuan-Yuan , Sun Xiao , Li Lei
Published: February 2023

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide, with a poor prognosis and high recurrence rate. Liver cancer stem cells (LCSCs), a small subset of HCC cells, have the capacity for self-renewal and the property of treatment resistance, suggesting that LCSCs are key factors in causing poor prognosis for HCC patients. In addition, LCSCs interact with immune cells to participate in the formation of an immunosuppressive microenvironment and escape the immune surveillance in HCC, especially lymphocytes. At present, immunotherapies for HCC are mainly based on reactivating the lymphocyte system, including immune checkpoint inhibitors, multifunctional antibodies, and adoptive cell therapy. Therefore, blocking the interactions between lymphocytes and LCSCs in combination with immunotherapy may be a promising therapeutic strategy. This review summarizes the interaction mechanisms of lymphocytes and LCSCs and the current exploration of combination therapy in HCC.
An analysis of market power and efficiency of Islamic banking in Indonesia and Malaysia
Authors: Mala Chajar Matari Fath , Hosen M Nadratuzzaman , Al Arif M Nur Rianto
Published: February 2023

Purpose – This paper aims to investigate whether the Islamic banking industry in Indonesia and Malaysia is collusive or efficient. Indonesian Islamic banking is expected to meet the Qualified ASEAN Bank (QAB) to compete with other Islamic banks, including Malaysia.Methodology – The data used in this study was panel data on Islamic banking in Indonesia and Malaysia from January 2010 to December 2019. Data analysis employed static panel data regression.Findings – The findings of the study disclosed no collusive behavior from Islamic banking in Indonesia and Malaysia to increase profitability. Meanwhile, market share has been shown to boost profitability in terms of equity, despite the fact that there is an endogeneity problem. Technical efficiency and scale efficiency in Islamic banking in Indonesia have been shown to significantly increase market share, but not profitability and market power. This study concludes that if Islamic banking market in Indonesia and Malaysia are opened and state boundaries are lifted, Indonesian Islamic banking still will not be able to compete since it has not been able to acquire economies of scale.Implications – Islamic banking in Indonedia needs to establish Islamic-Finance-Friendly Regulations. It is expected to pave the way for the value-added character of Islamic banking, it is the most important strategy to boost market share of Indonesian Islamic banking.Originality – This study seeks to fill the validation gap of endogeneity test in Islamic banking. There is the limitation on studies of Islamic banks since the validation of endogeneity test deal only with conventional banking studies.
Halal Food Literacy: Conceptual Framework, Dimension, and Scale Development
Authors: Khasanah Miftakhul , Dharmmesta Basu Swastha , Sutikno Bayu
Published: February 2023

This study aims to develop the Halal Food Literacy scale (HFL) concept and measurement. The concept of HFL in this study is based on the concept of literacy for consumers. In this case, the SDGs are the theoretical basis for building the HFL concept. Cognitive aspects related to Bloom's concept of Taxonomy were used as the basis for compiling this concept. The study includes four stages: developing, compiling, and describing the concept of Halal Food Literacy based on literature studies, interviews, discussions with experts and scholars, drafting items, testing the validity of the contents, and lastly, data testing with exploratory factor analysis. The results of the scale test revealed that there are four HFL factors, namely Halal awareness, Halal knowledge, Behavioral beliefs, and halal-related label beliefs. These four factors contributed 69.758% of the general variant and 57.828% of the variance from 11 items.
Vacuum Expansion and Collapse Inside an Infinite Shell
Authors: Laforet Christopher
Published: February 2023

The FRW model of cosmology assumes a Universe with uniform pressure and density everywhere in space at a given time. But at the largest scales, the Universe has a web-like structure surrounding large voids, violating these assumptions. Furthermore, a given region of spacetime is describable only by a single metric and therefore it cannot be that the Universe is modelled as an FRW perfect fluid since this would be the incorrect description of both the web and the voids. The cosmic web must be described by metrics with non-zero energy-momentum tensors with non-uniform pressure and density describing the matter within it. Therefore, the model of cosmology describing the expansion of the Universe must be a vacuum solution describing the empty spaces in the Universe surrounded by an infinite, massive shell (the surrounding Universe). The internal Schwarzschild metric is that model. The source of the Schwarzschild metric is shown to be at the event horizon, a location/time of infinite density, not at the singularity, as it is currently assumed. The spatial homogeneity of the metric is demonstrated by visualizing the geometry in the extrinsic "Kruskal-Szekeres" coordinates (visualized in 1+2 dimensions). Using the coordinate age of the Universe and transition redshift, this predicts the accelerated expansion, the Hubble diagram fits currently available cosmological data, and it gives a Hubble constant H0 of 71.6km/s/Mpc. The angular term of the metric describes the relativistic kinematic precession effect known as Thomas Precession which can be interpreted as spin about the time dimension.
Deep Learning for On-board Processing of Imaging Spectroscopy: A Survey
Authors: Ghasemi Nafiseh , Nieke Jens , Celesti Marco , Dicassimo Gianluigi
Published: February 2023

Modern hyperspectral imaging technologies generate enormous datasets that could potentially transmit a wealth of information, but such a resource presents numerous difficulties for data analysis and interpretation. Deep learning techniques undoubtedly provide a wide range of potential for solving both traditional imaging tasks and exciting new problems in the spatial-spectral domain. This is true in the primary application area of remote sensing, where hyperspectral technology originated and has made the majority of its progress, but it may be even more true in the vast array of now existing and developing application areas that make use of these imaging technologies. The current review advances on two fronts: on the one hand, it is directed at domain experts who desire an updated overview of how deep learning architectures might work in conjunction with hyperspectral acquisition techniques to address specific tasks in various application sectors. On the other hand, by providing them with a picture of how deep learning technologies are applied to hyperspectral data from (near)real-time perspective. The contributions of this review include the existence of these two points of view and the inclusion of opportunities and important problems associated with the development of future CHIME mission to be launched by European Space Agency (ESA).
The M-basis Functions and Their Application
Authors: Emadi Andani Mehran
Published: February 2023

A new set of basis functions is presented. The foundation in mathematics is established. To reconstruct a signal, it is compared to the Fourier basis functions. The M-basis functions' potential applications are also presented.
Beneš Network Based Efficient Data Concentrator for Triggerless Data Acquisition Systems
Authors: Gumiński Marek , Kruszewski Michał , Zabołotny Bartosz M. , Zabołotny Wojciech M.
Published: February 2023

The concentration of data from multiple links to a single output is an essential task performed by High-Energy Physics (HEP) Data Acquisition Systems (DAQs). At high and varying data rates combined with the large width of the concentrator’s output interface, this task is non-trivial. This paper presents a concentrator based on the Beneš network, which provides efficient concentration without using a high-frequency clock internally. It warrants that empty data are eliminated and does not disturb the data time-ordering if the data rates significantly differ between inputs. Additionally, it is well suited to FPGA implementation. It is based on simple data-routing primitives and may be fully pipelined.
Formação docente em contexto de rede, possibilidades diante da pandemia Covid-19
Authors: Silva Eliani Cristina Moreira da , Bizelli José Luís
Published: February 2023

O presente artigo tem como objetivo refletir sobre as possibilidades que a pandemia Covid-19, impôs aos sistemas de ensino, relacionadas a formação continuada docente no contexto de rede. Descreve-se e analisa as concepções de formação existentes no processo histórico, por meio da pesquisa bibliográfica e revisão da literatura, numa abordagem de análise qualitativa em educação. Apoia-se no referencial teórico: Scarpa (1998), Imbernón (2011, 2022), Tardif (2014), Placco e Almeida (2015) dentre outros. Na primeira seção far-se-á um histórico sobre as políticas formativas a partir do enfoque institucional. Na segunda seção será realizado a análise do desenho formativo adequado a nova realidade educacional. A terceira seção aponta para o planejamento educacional e políticas formativas. Por último apresenta-se a proposta formativa em contexto de rede diante da pandemia Covid-19. Destacam-se as possibilidades de um trabalho formativo que emerge da prática docente alicerçado no interior da própria rede de ensino.
Model Pembelajaran Problem Based Learning Mampu Meningkatkan Kemampuan Analisis Siswa
Authors: Jumini Jumini
Published: February 2023

The objective of research conducted at Karanganyar Vocational High School using the Problem-Based Learning (PBL) learning model is to 1) enhance students' analytic abilities and 2) increase student participation in creating side presentation materials with Canva. The design employed is quasi-experimental approach with a Pre-test and Post-test using two cycles with the planning, implementation, observation, and reflection stages. The subjects of this study were thirty-five students in tenth grade. Using instruments in the form of observation sheets and pre- and post-tests containing analysis and observation questions to assess the implementation of teaching and learning activities based on the PBL model. According to the findings of this study, the process of teaching and learning activities using the PBL model increased by 19.3% from cycle 1 to cycle 2, from 64.7% to 82.35%. Therefore, PBL was able to enhance students' analytical abilities.
Dynamics of Antibody Response to Yersinia pestis Proteins in Plague Affected Guinea Pigs
Authors: Gapel’chenkova T. V. , Shaikhutdinova R. Z. , Trunyakova A. S. , Svetoch T. E. , Kombarova T. I. , Platonov M. E. , Borzilov A. I. , Kopylov P. Kh. , Dentovskaya S. V.
Published: February 2023

Designing of new means for the specific prevention of plague, especially protein subunit vaccines, is impossible without studying the role of individual antigens in the manifestation of the pathogenic and immunogenic properties of Yersinia pestis. The aim of the present study was to determine the antibody levels to Y. pestis antigens in guinea pigs that survived infection with sub-lethal doses of virulent plague agent strains using enzyme immunoassay (ELISA). Materials and methods. Guinea pigs were inoculated subcutaneously with 30 CFU of the wild type Y. pestis subsp. Pestis strain 231 or non-capsular Y. pestis subsp. pestis Caf1-negative strain 358/12. Blood samples from sick or recovered guinea pigs were collected on day 15, 30, 60, and 90 after infection. The antibody response was assessed by 18 recombinant Y. pestis proteins in ELISA. Results and discussion. Heterogeneity of the antibody responses to the majority of the antigens with variation of IgG titers from animal to animal has been revealed. We observed increase in antibody titers by day 90 for the most analyzed antigens in the sera of the guinea pigs injected with wild type Y. pestis 231. On the contrary we found reduction in antibody titers by day 90 in case of inoculation with Y. pestis 358/12. The preservation of antibodies to Y. pestis proteins of different localization in the organism of the guinea pigs, as well functional activity, and the degree of representation on the surface of bacterial cell for a prolonged period of time indicates the multiplex nature of the plague immunity formation. Our ﬁndings are significant for the future design and development of effective vaccines against plague and the search for new targets for diagnostics of this disease.
Direct Quantification of Protein Antigens in Subunit Plague and Rickettsial Vaccine Preparations
Authors: Kopylov P. Kh. , Dentovskaya S. V.
Published: February 2023

The aim of the work was to put forward the methods for direct quantitative determination of the content of Yersinia pestis and Rickettsia raoultii protein antigens in preparations and various prototypes of subunit vaccines. Materials and methods. Y. pestis LcrV and Caf1 antigens enclosed in the substance of the molecular microencapsulated plague vaccine (MMPV) and separately, in microcrystals of amino acids co-precipitated with plague proteins were used as model antigens. R. raoultii Adr2, OmpB24, and YbgF antigens were adsorbed on the prototype substance of the rickettsia vaccine. The release of plague antigens from MMPV microcapsules was carried out through successive treatment of the latter with organic solvents, methylene chloride and methanol, respectively; the carrier microcrystals were dissolved in 0.1 M sodium citrate buffer at pH 6.0. The antigen content in the prototype substance of the rickettsial vaccine was determined by measuring the amount of proteins not bound to the alumogel. Quantitative parameters characterizing the content of antigens in the substances and prototypes of vaccine preparations were calculated by processing digital images of polyacrylamide gels obtained by electrophoresis of protein antigen fractions extracted from carriers. Results and discussion. Methods for direct extraction and subsequent quantitative analysis of Y. pestis LcrV and Caf1 antigens from subunit vaccine preparations based on amino acid microcrystals and polylactide microcapsules that do not cause protein degradation have been studied. A different nature of the binding of LcrV and Caf1 in the substances of microcrystals has been established, while the proportion of antigens released from microcrystals has been quantified only in case of their complete dissolution. It was found that at low concentrations of LcrV and Caf1 proteins extracted from microcrystals, it is necessary to concentrate the extracts with subsequent removal of salts for their reliable visualization. It has been confirmed that 10 μg of plague antigens and proteins of R. raoultii in a dose volume of 200 μl of suspension is sufficient for quantitative analysis using electrophoretic method. The prospects of other physicochemical methods alternative to direct extraction of antigens for evaluating the composition and quality of vaccine preparations are discussed.
The Infestation of Fleas of the Long-Tailed Souslik with Entomoparasitic Nematodes in Tuva Mountain Natural Plague Focus
Authors: Tokmakova E. G. , Galatsevich N. F. , Bazanova L. P. , Kovaleva N. I. , Chalbakai A. A. , Akimova I. S.
Published: February 2023

Entomoparasitic nematodes are supposed to be a link between parts of Yersinia pestis population in the environment and the flea vector. The aim of the study was to assess the prevalence and intensity of infestation in the fleas of the long-tailed souslik with entomoparasitic nematodes on the territory of Mongun-Taiginsky station in the Tuva natural plague focus. Materials and methods. Fleas were collected during the scheduled epizootiological surveys in 2019–2021. In the course of taxonomic identification the presence of parasitic nematodes was registered. In order to evaluate the intensity of nematode invasion, a total of 190 fleas were dissected. The number of adult parasitizing females and presence of larvae was recorded. Statistical processing of the data was performed with the help of conventional methods using the Excel software. The criterion χ2 was applied; the influence of various factors (species, gender of fleas) on the studied parameters was assessed through single- and two-factor analysis of variance. Results and discussion. During three years of observations, entomoparasitic nematodes were found in six species of fleas: Citellophilus tesquorum, Frontopsylla elatoides, Rhadinopsylla li transbaikalica, Frontopsylla hetera, Oropsylla alaskensis, and Neopsylla mana. The differences in infestation with nematodes between the species are presented. The highest invasion rate – 25.1–25.6 % – is observed in Rh. li transbaikalica. The gender of leas does not influence their infestation. It is established that invaded fleas are more often found in the nest than in the fur of animals, they are less actively migrate to the burrow entrance compared to not invaded ones. Evaluation of infestation prevalence has revealed that fleas Rh. li transbaikalica are the hosts for nematodes of mono- or oligoxenic species, which do not occur in other fleas.
DEVISING AN INDONESIAN LEGAL ARCHITECTURE FOR METAVERSE BANKING: CHALLENGES AND OPPORTUNITIES
Authors: Pratama Kristianus Jimy
Published: February 2023

The objective of this research is to correct misconceptions about the metaverse and metaverse banking, as well as to refute national legal perspectives on metaverse banking. It is designed to also shed some light on challenges and opportunities connected to the plan of legal architecture on metaverse banking along with its supervision and enforcement mechanisms. Metaverse banking consists of banking activities in the metaverse ecosystem. Due to the rapid development of metaverse banking on a global level and unresponsive national regulations to govern it, there is no adequate legal regulation for this activity in Indonesia. The research method is normative through literature study. This research findings illustrate persistent errors about the concept of metaverse banking including the national legal authority’s perspective on the substance of regulation. The results also show that challenges and opportunities exist for devising a legal architecture on metaverse banking accompanied by a mechanism for supervision and dispute resolution. This research contributes to as well as serves as one of the references for study on metaverse banking in Indonesia
Pengembangan Sistem Pendeteksi Kebocoran LPG Menggunakan Infrastruktur Instant Messaging Berbasis Internet of Things
Authors: Kholil Moch , Ismanto Ismanto , Akhsani Rafika
Published: February 2023

AbstrakPerkembangan teknologi yang semakin pesat seiring dengan pekerjaan manusia yang semakin banyak, menjadikan peran teknologi sebagai upaya optimalisasi dalam membantu pekerjaaan manusia sangat dibutuhkan. Salah satu tren teknologi yang menarik dan berkembang adalah teknologi Internet of Things atau biasa disingkat dengan IoT. Pemanfaatan Internet of Things juga sangat membantu dalam sistem pemantauan jarak jauh. Sebagai salah satu bentuk pemanfaatannya adalah sistem pendeteksi jarak jauh terhadap kebocoran Liquified Petroleum Gas (LPG) pada dapur sebuah rumah tangga, restoran maupun industri sehingga pemilik bisa melakukan pencegahan dini apabila terjadi sebuah kebocoran di dalam ruangan dan mampu memberikan peringatan dini kebocoran LPG saat ditinggal bepergian. Sistem dikembangkan melalui 4 tahapan, mulai dari pengumpulan data, perancangan perangkat keras, penulisan kode program dan uji coba sistem. Penelitian ini bertujuan menghasilkan sebuah alat pendeteksi kebocoran LPG berbasis IoT, dimana alat ini mampu mendeteksi serta mengirimkan pesan peringatan dini saat terjadi kebocoran LPG baik melalui pesan telegram maupun buzzer yang terpasang di perangkat. Dengan mengacu pada standarisasi yang dikeluarkan oleh Badan Standardisasi Nasional tentang Nilai Ambang Batas zat kimia di udara tempat kerja, sistem telah bekerja dengan baik dengan mampu memberikan peringatan kebocoran LPG saat Nilai Ambang Batas (NAB) zat kimia mencapai 1000 bds/ppm.Kata kunci: IoT, telegram, LPG, ppm Abstract[Development Of LPG Leak Detection System Using Instant Messaging Infrastructure Based On Internet Of Things]Developments of technology along with human work are growing, making the role of technology as an optimization effort in helping human work needed.  One of the technologies that are developing is the Internet of Things or commonly abbreviated as IoT. Utilization of the Internet of Things is also very helpful in remote monitoring systems. One form of utilization is a remote detection system for Liquefied Petroleum Gas (LPG) leaks in the kitchen of a household, restaurant, or industry so that owners can take early prevention in the event of a leak in the room and are able to provide early warning of LPG leaks when left traveling. The system is developed through four stages, starting from data collection, hardware design, writing program code, and system testing. This study aims to produce an IoT-based LPG leak detector, which a tool that is able to detect and send an early warning message when an LPG leak occurs either through a telegram message or a buzzer installed on the device. By referring to the standard issued by the National Standardization Agency regarding the Threshold Value of chemicals in the workplace air, the system has worked well by being able to provide an LPG leak warning when the Threshold Value of chemical substances reaches 1000 ppm.. Keywords: IoT; telegram, LPG; ppm
O papel da sociedade civil na inovação e incorporação de dispositivos médicos no Brasil
Authors: Toscas Fotini , Oliveira Vivian , Silva Aline
Published: February 2023

Objetivo: Abordar o contexto normativo quanto aos processos de participação social nas fases de Pesquisa, Desenvolvimento e Inovação (PD&I) e aos processos de regulação sanitária e de avaliação para incorporação de tecnologias no Sistema Único de Saúde (SUS). Métodos: Pesquisa exploratória descritiva com revisão dos referenciais normativos e análise documental: i) nos marcos regulatórios de inovação brasileiros; ii) na regulação sanitária pela Agência Nacional de Vigilância Sanitária (Anvisa); e iii) na avaliação e incorporação de dispositivos médicos na Comissão Nacional de Incorporação de Tecnologias em Saúde no SUS (Conitec). Resultados: Nos sites das instituições governamentais de fomento à Ciência, Tecnologia e Inovação (CT&I) vinculadas ao Ministério da Ciência, Tecnologia e Inovações (MCTI), observaram-se mecanismos de participação social estabelecidos na legislação. No contexto regulatório, a participação social se insere desde a construção dos regulamentos até etapas-chave do ciclo de vida da tecnologia. Na avaliação de tecnologias, verificou-se ampliação das estratégias de participação, a exemplo da “perspectiva do paciente” na plenária. Entre 64 chamadas públicas realizadas, cinco foram sobre dispositivos médicos. Conclusão: Evidenciou-se a importância da participação social em todas etapas do ciclo de vida dos dispositivos médicos, tendo em vista as especificidades dessas tecnologias. A Anvisa e a Conitec têm ampliado os mecanismos de participação para além dos preconizados em lei. Já nas etapas de PD&I, as iniciativas são incipientes, sendo localizadas ações conforme previsão legal. A ampliação de mecanismos de participação efetiva favorece a construção de soluções para minimizar os desafios de saúde, além de promover maior transparência, valor para a sociedade e confiança nas decisões em saúde brasileira.
Children’s healthy and unhealthy food intake related to parental fear of the COVID-19, family communication patterns, and parental controlling feeding practices
Authors: Kim Kay W. , Wallander Jan L.
Published: February 2023

The COVID-19 pandemic in 2020 changed the daily lives of families, including their food environments. We tested a conceptual model of potential influences on children’s dietary intake under these conditions. 306 (51% fathers) parents with children ages 5- 12 were recruited for an online study, where they completed questionnaires to measure fear of COVID-19, family communication patterns, parental controlling feeding practices, and child’s healthy and unhealthy food intake. Structural equation modeling was used, including a multi-group analysis to compare mothers and fathers. Parental fear of COVID-19 was positively related to communication patterns, which were positively associated with parental controlling feeding practices. Communication patterns were also linked to child unhealthy food intake, but only for mothers. General family communication patterns play an important role in children’s dietary intake. Therefore, it may be useful to help parents adopt general positive parenting approaches to influence their children’s healthy development.
Trend of sociodemographic and economic inequalities in the use of maternal health services in Lao People’s Democratic Republic from 2006 to 2017: MICS data analysis
Authors: Ahissou Noudéhouénou Credo Adelphe , Nonaka Daisuke , Takeuchi Rie , Reyes Calvin de los , Uehara Manami , Khampheng Phongluxa , Kounnavong Sengchanh , Kobayashi Jun
Published: February 2023

Background
Maternal mortalities remain high in Lao People’s Democratic Republic (Lao PDR). To improve access to maternal health services for all women, the country adopted a policy to remove user fees for childbirth-related care (“Free Maternal Health Service” [Free MCH] policy) in 2012. However, it remains unclear whether the policy has reduced inequalities in access to services. Our study assessed the trends and magnitude of sociodemographic and economic inequalities in access to health services before and after adoption of the Free MCH policy.
Methods
We used the three most recent Lao Social Indicator Survey datasets for this analysis. We assessed wealth, area of residence, ethnicity, educational attainment, and women’s age-related inequalities in the use of at least one antenatal care (ANC) visit with skilled personnel, institutional delivery, and at least one facility-based postnatal care (PNC) visit by mothers. The magnitude of inequalities was measured using concentration curves, concentration indices (CIX), and equiplots.
Results
Overall, the coverages of at least one ANC visit with skilled personnel and institutional delivery increased from 35.7–78.4% and 23.1–65.5% respectively, between the years 2006 and 2017. These coverages almost doubled in all social groups from 2011–12 to 2017 compared to 2006 to 2011–12. Meanwhile, the use of at least one facility-based PNC after discharge rose only from 2.3–3.7% between 2011–12 and 2017. Despite the decreases in service utilization gaps between groups, inequalities in favor of the rich, the most educated, and the majority ethnic groups remained the highest, particularly for facility-based deliveries. The CIX in 2017 were 0.193, 0.139, and 0.120, respectively, for these factors (p < 0.001).
Conclusion
During the study period, uptake of maternal health services improved, and sociodemographic and economic inequalities decreased. The highest improvement since adoption of the MCH policy occurred among the least-favored women. Future interventions should promote outreach services, awareness raising, and a woman-centered approach to care. More attention should also be given to improving the uptake of facility-based PNC visits.
A study on the Water quality and the change detection of aquatic vegetation of Satajaan beel, North Lakhimpur, Assam
Authors: Bhuyan Jintu Moni , Sharma Pallavi
Published: February 2023

Water quality assessment is one of the important processes to understand the environmental status of the wetland. The study is carried out to analysis of the water quality and change detection of aquatic vegetation in Satajaan Wetland, situated in Lakhimpur, Assam in the floodplain of Ranganadi river. 10 water sample has been collected from the selected samples station through random sampling method to understand the quality of water. For the study we have assessed Physical parameters like temperature, pH, Electric Conductivity, Total dissolved solid and chemical parameters such as Salinity, alkalinity, CO2, Dissolved oxygen, Cl-, Total Hardness, Ca2+, Mg2+, Na+, K+, SO42-, NO3-, F-, PO43 etc. For the statistical analysis of the water parameter, we have done Correlation coefficient analysis, PCA and HCA. WQI of the study area has been also observed by using weighted arithmetic method. Along with the water quality parameter we also try to analysis the change of area of aquatic vegetation in the study area using NDVI. From the NDVI calculation it has been observed that the area of the aquatic vegetation in the study area has been decreaded year by year. The rate of degradtion of aquatic vegetation in the study area is calculated 2.84 acer or 7.84%.
Prospective Observational Study on Clinical and Epidemiological Profile of Adult Patients Presenting to the Emergency Department with Upper Gastrointestinal Bleed
Authors: Raj Alok , Kaeley Nidhi , Prasad Hari , Patnaik Itish , Bahurupi Yogesh , Joshi Shrirang , Shukla Krishna , Galagali Santosh , Patel Sanket
Published: February 2023

Background and objective: Bleeding from the upper gastrointestinal (GI) tract is one of the common medical emergencies. In this study, we assessed patients' socio-demographic and clinical characteristics and the association of clinical characteristics with treatment outcomes among patients with upper gastrointestinal bleed (UGIB) presenting to the emergency department (ED). At present, there is a scarcity of data on UGIB in Northern part of India.
Material and method: The study was a single-center,prospective observational study conducted at an urban tertiary care center. Consecutive patients with UGIB were enrolled in the study from August 2020 to February 2022. A detailed history was obtained, including demographic data such as age and sex, presenting complaints, history of presenting illness, history related to co-morbidities, addiction, and drug history. Pre-endoscopic Rockall and Glasgow-Blatchford Score were calculated for each patient. The patients were subsequently followed up till discharge from the hospital. The final outcomes with regard to mortality, need for blood transfusion, length of ED, and hospital stay and discharge were noted.
Result: 141 patients were included in the study. The mean age of the patients with UGIB was 48 ± 14 years. 115 (81.6%) patients were male. The most common co-morbidity was chronic liver disease (40;28.4%). The most frequent presenting complaint in this study was hematemesis (96; 68.1%), followed by melena (76;53.9%). The mean (SD) of the Rockall Score was 2.46 ± 1.75. The mean (SD) of the Glasgow Blatchford Score was 12.46 ± 3.15 in patients with UGIB.
Conclusion: In our study, hematemesis was the most prevalent symptom of an UGIB, followed by melena. Portal hypertension was the more common cause of UGIB. Alcohol intake, NSAIDs abuse, and co-morbidities such as underlying chronic liver disease, hypertension, and diabetes are statistically significantly associated with UGIB. By doing early endoscopy we can find and treat the cause of bleeding, thereby we can prevent morbidity, mortality and decrease the length of hospital stay.
First report of environmental isolation of Cryptococcus spp. from Boyacá - Colombia
Authors: Briggith-Nathalia Serna-Espinosa , Maribel Forero-Castro , Eugenia Morales-Puentes María , Marcela Parra-Giraldo Claudia , Patricia Escandón , Adriana Sánchez-Quitan Zilpa
Published: February 2023

Background
The Cryptococcus genus comprises more than 80 species, of which C. neoformansand C. gattii are the leading cause of cryptococcosis. The distribution of C. gattii and C. neoformans complex has been extensively studied and widely reported globally. Other species such as C. albidus, C. laurentii, and C. flavescens have been reported as pathogenic yeast. Since there are no reports of environmental isolation in the Boyacá region (Colombia), this study aimed to isolate and characterize the species of Cryptococcus from pigeon feces, eucalyptus, and olive trees distributed in the municipalities of Tunja and Ricaute Alto.
Results
The environmental data was recovered, and the isolations obtained were identified by microscopy, biochemical test, MALDI-TOF, RFLP of the URA5 gene, and sequencing of the ITS and LSU gene.
For the 93 pigeon dropping samples collected in Tunja, 23 corresponded to C. neoformans, 3 to C. saitoi, 2 C. albidus and 1 to C. laurentii. Of the 1188 samples collected from olive trees, 17 (1.43%) positive samples were identified as C. gattii (4), C. neoformans var. grubii (2), C. laurentii (3), C. albidus (2), C. saitoi(5) and C. flavescens (1). Likewise, specimens of C. neoformansvar. grubii presented molecular type VNI and molecular type VNII; for C. gattii the molecular types found were VGIII and VGIV.
Conclusions
Therefore, it can be concluded that the species of Cryptococcus genus, are present in the environment of Boyacá, and show a predilection for climate conditions that are typical of this region.
A viable varying speed of light model in the RW metric
Authors: Lee Seokcheon
Published: February 2023

The Robertson-Walker (RW) metric allows us to apply general relativity to model the behavior of the Universe as a whole (\textit{i.e.}, cosmology). We can properly interpret various cosmological observations, like the cosmological redshift, the Hubble parameter, geometrical distances, and so on, if we identify fundamental observers with individual galaxies. That is to say that the interpretation of observations of modern cosmology relies on the RW metric. The RW model satisfies the cosmological principle in which the 3-space always remains isotropic and homogeneous. One can derive the cosmological redshift relation from this condition. We show that it is still possible for us to obtain consistent results in a specific time-varying speed of light model without spoiling the success of the standard model. The validity of this model needs to be determined by observations.
Activated carbon/ZnO-Ni nanoflower composite as an efficient photocatalyst for enhanced degradation of reactive red 120 dye under LED light
Authors: Norozi Kousar , Mansouri Mohsen , Karamian Elham , Maleki Basir
Published: February 2023

In this research, ZnO doped Ni was immobilized over activated carbon nanoparticles, and the prepared photocatalysts were characterized by FTIR, XRD, SEM, EDS, and BET analyses and used for the degradation of reactive red 120 (RR120) dye under LED light irradiation. The C/ZnO-Ni photocatalyst demonstrated a flower-like morphology with mesoporous features. The effect of the main parameters like Zn:Ni molar ratio, photocatalyst amount, carbon mesh size, solution pH, initial RR120 concentration, H2O2 and power of LED lamp was investigated to maximize the efficiency of RR120 degradation. The best photocatalytic RR120 degradation of 94.88% was observed under the optimum conditions in which Zn:Ni molar ratio, photocatalyst amount, carbon mesh size, solution pH, initial RR120 concentration, H2O2 and power of LED lamp were adjusted at 1:2, 50 mg, 270, 3, 5 ppm, 0.2 mL and 50 W, respectively. Kinetic studies confirmed the applicability of the Langmuir-Hinshelwood theory by which the dye concentration is a first-order function of time. The reusability study of the C/ZnO-Ni photocatalyst showed good stability of the photocatalyst after recycling 7 times under the optimum conditions.
Electrochemical oxo-functionalisation of cyclic alkanes and alkenes using nitrate and oxygen
Authors: Nikl Joachim , Hofmann Kamil , Mossazghi Samuel , Möller Isabel , Mondeshki Daniel , Weinelt Frank , Baumann Franz Erich , Waldvogel Siegfried
Published: February 2023

Direct functionalization of C(sp3)–H bonds allows a fast, synthetic access to valuable products, starting from simple petrochemicals. Chemical transformation of inactivated methylene groups, however, remains challenging for organic synthesis. Here, we present a general electrochemical method for the oxidation of C(sp3)–H and C(sp2)–H bonds, in which cyclic alkanes and (cyclic) olefins are converted into cycloaliphatic ketones as well as aliphatic (di)carboxylic acids. This resource-friendly method is based on nitrate salts in a dual role as anodic mediator and supporting electrolyte, which can be fully recovered and recycled. Reduction of molecular oxygen as cathodic counter reaction leads to an efficient convergent use of both electrode reactions. By avoiding the use of transition metals and chemical oxidisers, this protocol represents a sustainable oxo-functionalization method, leading to a valuable contribution for the sustainable conversion of petrochemical feedstocks into synthetically usable fine chemicals and commodities.
An updated and unified earthquake catalog of Bangladesh for seismic hazard assessment
Authors: Rana Sohel , Bhuiyan M. Abdur Rahman , Ali Shafayat Bin , Mukhlis Mohammad Raihan
Published: February 2023

A comprehensive earthquake catalog is an important input for reliable seismic hazard assessment. In the present study, an updated and unified earthquake catalog has been compiled for Bangladesh covering 150N–320N and 830E–980E. A large number of earthquake event data has been collected from various sources including ISC–GEM Catalog, USGS catalog, ISC Bulletin, etc. Collected data have then been compiled and fake or duplicate events have been eliminated. Earthquake magnitudes that were not reported in moment magnitude (Mw) have been converted to Mw using conversion relations compatible with regional earthquake events. The compiled earthquake catalog consists of 8,024 earthquake events with magnitudes 3.56 ≤ Mw ≤ 8.8 for the period of 825 to 2021. Declustering of the catalog has been performed to remove the foreshocks and aftershocks which results in 7,219 earthquakes in the final catalog. A completeness analysis has been performed for the final catalog. This study proposes Gutenberg-Richter’s earthquake magnitude-frequency relationships for the whole region as well as for five selected regions based on the existing faults within the country. This study provides a database with a solid background for future works in the field of seismicity, seismic hazard assessment, and ground response studies for the country.