bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelling and Simulation of Patient Flow in the Emergency Department During the COVID-19 Pandemic Using Hierarchical Coloured Petri Net
Authors: Louhab Zouaoui , Boufera Fatma
Published: September 2022

The emergency department (ED) faces great challenges during the corona pandemic, which has greatly affected the course of work, as the medical staff works to maintain the quality of service and more guarantee the health of patients and staff. With the rapid spread of the coronavirus, ED has become the focus of attention of many researchers, where most of them focused on reducing waiting time and the duration of the patient's length of stay (LOS) through the restructuring of ED. In this study, the authors propose a simulation model using the hierarchical coloured-petri nets (CP-Nets). Several improvement scenarios have been suggested in order to arrive at the optimal solution. Scenarios were compared and solutions were presented to decision makers. This study was conducted at the Hassani Abdelkader Hospital in Sidi Bel Abbes. The authors obtained a model that could be generalized to other hospitals.
A Two-Level Multi-Modal Analysis for Depression Detection From Online Social Media
Authors: Sarkar Dhrubasish , Kumar Piyush , Samanta Poulomi , Dutta Suchandra , Chatterjee Moumita
Published: September 2022

According to World Health Organization statistics, depression is a prominent cause of concern worldwide, leading to suicide in the majority of these cases if left untreated. Nowadays, social media is a great place for users to express themselves through text, emoticons, images, etc., which reflect their thoughts and moods. This has opened up the possibility of studying social networks in order to better comprehend the mental states of their participants. The primary goal of the research is to examine Twitter user personas and tweets in order to uncover traits that may signal depressive symptoms among online users. A two-level depression detection method is proposed in which suspected depressed individuals are identified using social media features, personality traits, temporal and sentiment analysis of user biographies. Using the support vector machine classifier, these qualities are integrated with additional linguistic and topic features to achieve an accuracy of 89%. According to the research, effective feature selection and their combinations aid in enhancing performance.
An Efficient Parallel Hybrid Feature Selection Approach for Big Data Analysis
Authors: Azaiz Mohamed Amine , Bensaber Djamel Amar
Published: September 2022

Classification algorithms face runtime complexity due to high data dimension, especially in the context of big data. Feature selection (FS) is a technique for reducing dimensions and improving learning performance. In this paper, the authors proposed a hybrid FS algorithm for classification in the context of big data. Firstly, only the most relevant features are selected using symmetric uncertainty (SU) as a measure of correlation. The features are distributed into subsets using Apache Spark to calculate SU between each feature and target class in parallel. Then a Binary PSO (BPSO) algorithm is used to find the optimal FS. The BPSO has limited convergence and restricted inertial weight adjustment, so the authors suggested using a multiple inertia weight strategy to influence the changes in particle motions so that the search process is more varied. Also, the authors proposed a parallel fitness evaluation for particles under Spark to accelerate the algorithm. The results showed that the proposed FS achieved higher classification performance with a smaller size in reasonable time.
The Effects of Navigation Cues and Involvement of Highly Innovative Consumers on Attitudes Toward Mobile Application Stores
Authors: Liu Chi-Lun , Huang Hsieh-Hong , Yen David C.
Published: September 2022

In the e-commerce area, navigation cues play an important role that guides consumers while they are browsing products in online stores. Best-seller lists and product categories are typically used as navigation cues. With the rapid growth of smartphone penetration around the world, the role of navigation cues has become more critical to consumers who enjoy buying products and applications via mobile application stores. The purpose of this study is to investigate the relationships among navigation cues, attitudes, and involvement of users in mobile stores based on the elaboration likelihood model. A laboratory experiment was conducted, and the experiment results indicate that consumers with high involvement have better attitudes toward the product categories approach compared to the best-seller list approach. The fits of navigation cues and mobile consumer characteristics may contribute to the mobile application store design strategy.
Consumer Engagement on Social Networking Sites
Authors: Bai Shizhen , Yin Yue , Wu Ye , Zhang Justin Zuopeng , Yu Yubing , Jasimuddin Sajjad M.
Published: September 2022

In spite the significance of consumer engagement that scholars have recognized, there is a gap in understanding the influencing factors of consumer social networking engagement behaviors. In the light of social identity theory, this study considered susceptibility to interpersonal influence (SIPI) and self-expressive brands (SEBs) on consumer social networking engagement behaviors. Data from our research demonstrated that SEBs and SIPI were positively related to brand attachment, which also impacted liking, sharing, and commenting on social networking sites (SNS). In addition, brand attachment played a positive mediating role among SEB, SIPI, and consumer engagement on SNS. The research explores the factors affecting consumer engagement on SNS with a new insight and guides brand managers to seek efficient ways to drive consumers to engage on online social networks.
An Empirical Study on Selection, Evaluation, and Management Strategies of Green Suppliers in Manufacturing Enterprises
Authors: Wu Chia-Huei
Published: September 2022

Green supply chain management means integrating environmental awareness into supply chain management, including product design, raw material acquisition and selection, the manufacturing process, the distribution of final products to customers, and the management of end-of-life products. However, there are driving and unfavorable factors for manufacturing enterprises to choose green suppliers. Therefore, this study proposed a new IPA-DEMATEL model by integrating importance-performance analysis (IPA) and decision-making trial and evaluation laboratory (DEMATEL) to explore green suppliers' selection, evaluation, and management strategies.
COVID-19 lung lesion treated with pirfenidone and effective rehabilitation: A Case Report
Authors: Zaldívar Vázquez L. , Meneses Calderón J. , Ochoa Morales C. F. , Mendieta Zerón H.
Published: September 2022

SARS-CoV-2 leads to an inflammatory and fibrotic state in the lungs which can be the cause of death and even in those who survive cause a functional limitation.
A male patient of 28 years with COVID-19 was treated with nitazoxanide 500 mg 6 hourly, ibuprofen 500 mg 8 hourly, levofloxacin 500 mg  and vitamin D 4,000 IU 24 hourly, and pirfenidone (K-LP) 1,200 mg 12 hourly. The patient was ventilated and extubated after 13 days in the intensive care unit. He was then immersed in a strict rehabilitation programme based on re-teaching the diaphragmatic respiratory pattern.
Pirfenidone at a dose of 1,200 mg twice a day could be considered as a valid option to reduce  lung fibrosis caused by the SARS-CoV-2 virus. To ensure optimal recovery, pulmonary rehabilitation therapy should be added to the management.
TANGGUNG JAWAB PENDIDIKAN IMAN PADA ANAK USIA DINI
Authors: SALEH SUMANTI M , CHAIRUNNISA CHAIRUNNISA
Published: September 2022

Diantara tanggung jawab besar yang jelas diperhatikan dan disoroti oleh islam juga oleh penalaran logika, adalah tanggung jawab seorang pendidik terhadap orang-orang yang berada dipundaknnya berupa tanggung jawab pengajaran dan pendidikan iman. Ini sesungguhnya bukan tanggung jawab kecil dan ringan, karena tanggung jawab ini telah dituntut sejak seorang anak dilahirkan hingga ia mencapai usia remaja, bahkan sampai ia menginjak dewasa yang sempurna. Tanggung jawab pendidikan iman adalah meningkat anak-anak dengan dasar-dasar keimanan sejak ia mengerti, membiasakan dengan rukun iman dan rukun islam sejak ia memahami dan mengajarkan kepadanya dasar-dasar syariat sejak usia tamyiz. Menumbuhkan dasar-dsar pendidikan iman dan ajaran islam sehingga anak akan terikat dengan Islam baik aqidah atau ibadahnya.
DESENTRALISASI PENDIDIKAN DI ERA OTONOMI DAERAH KONSEP, IMPLEMENTASI, DAN KENDALANYA
Authors: AZIS H.SULAIMAN L.
Published: September 2022

Desentralisasi pendidikan adalah  pelimpahan kewenangan berupa pengaturan, pengurusan, pembinaan, pengawasan dan substansinya, kurikulum, mutu pembelajaran, kualifikasi guru, dan infrastruktur pada unit layanan pendidikan dari pemerintah pusat kepada pemerintah kabupaten/kota.Sasaran pengelolaannya mencakup 3 langkah strategis, yakni peningkatan pemerataan dan perluasan kesempatan untuk memperoleh pendidikan yang bermutu; pengembangan wawasan persaingan dan keunggulan bangsa; memperkuat keterkaitan pendidikan agar sepadan dengan kebutuhan pembangunan (link and match).Dalam implementasinyaterkendala beberapaproblema, terutama kurikulum, sumber daya manusia, dana, serta sarana-prasarana pendidikan. Keberhasilan desentralisasi pendidikan selain komitmen Pemda dalam pembinaan organisasi kelembagaan dan kordinasi, juga  membutuhkan profesionalitas supervisor dalam melaksanakan pembinaan profesionalguru
PERSEPSI KONSEPTUALITAS PERAKITAN BUTIR SOAL
Authors: Marengke Musa
Published: September 2022

Tes pengembangan pada dasarnya harus membuat dua keputusan, yaitu apa yang diukur dan bagaimana mengukurnya. Perakitan item yang berkaitan dengan keputusan kedua. Jika seorang guru bekerja berdasarkan item spesifikasi, maka dengan sendirinya struktur dan format gandum harus ditetapkan. Tetapi jika guru tidak berdasarkan spesifikasi item, perlu untuk menetapkan format jika item yang harus diikuti sebelum butir mulai menulis tahap. Di sinilah keahlian dan ketelitian yang dibutuhkan guru. Guru perlu mengetahui prosedur mengumpulkan barang, baik secara konseptual maupun teknis-operasional. Secara konseptual, tahapan masalah perakitan telah menawarkan ide tentang bagaimana mengukur tingkat kesulitan, tingkat daya yang berbeda, tentang validitas dan reliabilitas. Prosedur ini perlu dianalisis dalam esai ini dengan menganalisis konsep-konsep tentang teori item. Hal ini dapat dianalisis dengan kacamata-deskriptif kualitatif dan kuantitatif-matematis. Pikiran bermaksud menganalisis masalah dan menetapkan posisi materi pada setiap kriteria. Masalah yang memenuhi syarat salah satunya dapat diukur dari elemen representasi dari semua kompetensi prikomotoriknya. Selain itu, pertanyaan harus valid dan dapat dipercaya, yang memiliki tingkat validitas dan reliabilitas tertentu. Makalah ini bertujuan untuk memeriksa prosedur perakitan Anda dalam masalah persepsi konseptualitas. Maka artikel ini akan memeriksa item dalam persepsi penggunaan item, masalah kualitas dan langkah-langkah perakitan dan analisis.
KEMAMPUAN MENGAJAR GURU TERHADAP HASIL BELAJAR SISWA
Authors: Ismail Radjiman
Published: September 2022

Kemampuan seorang guru terhadap strategi pembelajaran merupakan faktor penting yang berkaitan dengan hasil belajar siswa. Diasumsikan bahwa pengetahuan yang baik memiliki efek yang baik terhadap pembelajaran yang baik. Sikap mengajar dan motivasi guru akan berpengaruh terhadap hasil belajar siswa. Terdapat keterkaitan yang positif antara pengetahuan guru, strategi pembelajaran, sikap mengajar dan motivasi guru yang berdampak pada hasil belajar siswas.
Menentukan Bentuk Kuadrat Bagian Kerucut Dan Permukaan Kuadratik dengan Menggunakan Matriks
Authors: Said Arwan Mhd
Published: September 2022

In determining  quadratic forms by using the matrix, the way is to eliminate the tribe the product of  a quadratic form, ie with how to change variables, and will use the results to assess  the graph Conic sections (slices or cross-section of the cone, or conic section ).Problems in this study is how to determine the quadratic forms of conic sections and quadratic surfaces with using Matrix. From these results, it can be concluded that determine the shape of squares of conic sections and quadratic surfaces can be determined by using a matrix
The amphibians of Pará, Brazil
Authors: Cassundé Gisele Ferreira , Sturaro Marcelo José , Maciel Adriano Oliveira , Prudente Ana Lúcia da Costa , Sarmento João Fabrício Melo , Peloso Pedro
Published: September 2022

Pará is the second largest state in Brazil, with all its territory within the Amazonian rainforest. The state has a wide variety of habitats and bioregions and is home to a large diversity of species. In the race to uncover this diversity and to provide support for future research, we have compiled the first list of amphibian species occurring in Pará, based on the identification of specimens deposited in scientific collections and analysis of primary literature. We recorded 195 species of amphibians, 30 of which are endemic to the state, and five represented new occurrence records. Despite its large territory, high number of endemic species and very intense levels of deforestation, only five species are officially considered threatened with extinction. We discuss reasons as to why so few species are threatened and why this number is likely to increase soon. We also discuss issues related to taxonomy, such as the occurrence of multiple unnamed species that have already been discovered in Pará. Finally, we highlight some opportunities and challenges for future research areas with amphibian diversity and taxonomy in the state of Pará.
Centros de gestão do território no sudeste da Amazônia Oriental
Authors: Sodré Reges , Macêdo Oliveira Helbaneth
Published: September 2022

A região sudeste da Amazônia Oriental integra o que Becker (2009) chamou de arco do povoamento consolidado, porção territorial amazônica que concentra o cerne da economia regional. Diante disso, esse trabalho procura identificar e analisar os principais centros que comandam esse segmento de rede urbana, considerando a gestão pública e econômica do território. A pesquisa foi realizada com base em revisão bibliográfica e análise dos micro-dados da publicação Regiões de Influência das Cidades - REGIC (IBGE, 2020). Constatou-se que a região possui três níveis de gestão territorial: no topo, estão as cidades de Palmas, Marabá e Imperatriz, estabelecendo interações de gestão que ultrapassam a região; em nível intermediário, encontra-se cidades que são focos de investimentos nacionais e de instalação de uma gama de serviços públicos, mas com reduzida capacidade de construir interações city-ness, tendo seus territórios como ponto de partida; e, no terceiro nível, está um conjunto de cidades cujas interações predominantes são de tipo town-ness.
A comida como linguagem e o mercado como cozinha: a alimentação em mercados públicos enquanto um símbolo social
Authors: Neves Mariana Rodrigues da Costa , Souza de Deus José Antônio
Published: September 2022

O objetivo deste artigo é fazer uma reflexão e análise sobre a simbologia do alimentar-se em mercados públicos e problematizar sobre a estratégia metodológica de um estudo de caso realizado no Mercado Municipal de Diamantina (MG). Baseando-se em um marco teórico pautado nos conceitos de “comida-linguagem” e “cozinha-mercado” presentes na obra de Lévi-Strauss (1991; 2006) e “habitus” de Bourdieu (1987; 1998) aos quais se agrega a clássica categoria geográfica Lugar, a partir de cuja reelaboração compreendeu-se que historicamente o Mercado revela-se como um espaço passível de intervenções sociais e políticas públicas, não relacionados apenas a fatores econômicos- vale ressaltar-, e visualizando tal estabelecimento público como um Lugar que simboliza a reprodução e construção de uma cultura popular local e no qual o “habitus” de alimentar-se vincular-se-ia a diversificadas identidades intrínsecas aos frequentadores, como a regional, familiar, comunitária e rural/ urbana.
Shared decision-making in Latin America
Authors: Palacios Alberto
Published: September 2022

Shared decision-making in medicine is the ideal to which both physicians and patients aspire.
İnanç Temelli Suriyeli Mülteci Topluluklar’da Geri Dönüş Eğilimleri
Authors: KAYA Mahmut
Published: September 2022

Kapsam: Bu çalışmada inanç temelli Suriyeli mülteci topluluklarda Suriye’ye geri dönüş eğilimleri sorunsallaştırılmıştır.

Amaç: Araştırmanın amacı geri dönüş konusunun Suriyelilerin perspektifinden nasıl algılandığını ortaya koymaktır.

Yöntem: Nitel yöntem yaklaşımı ile ele alınan çalışmada inanç temelli topluluklardaki topluluk üyesi ve grup liderlerini kapsayan 19 kişi ile derinlemesine bireysel görüşmeler yapılmıştır.

Bulgular: Araştırma bulgularına göre, inanç temelli Suriyeli mülteci topluluklarda geri dönüşe ilişkin iki ana yaklaşım ortaya çıkmaktadır. Bunlar, ilk olarak tümüyle geri dönüşü reddedenler, ikinci olarak da şartlı geri dönüşü kabul edenlerdir. Geri dönüşü tümüyle reddedenlerin gerekçeleri: rejim ve örgütler karşısında can güvenliğinin olmayışı, savaşın yıkıcı sonuçları, aile ve akrabaların kaybı, rejime muhalif olma, hakların teminat altında olmaması, rejimin halen görevde olması, vatandaşlık almış olma ve görece entegre olup Türkiye’de bir düzen kurmuş olma şeklinde sıralanmaktadır. Şartlı geri dönüşü kabul edenler ise savaşın sona ermesi, güvenlik ve alt yapı hizmetlerinin sağlanmış olması, mevcut rejiminin değişmesi, inanç özgürlüğünün sağlanması gibi gerekçeleri ileri sürmektedir.

Özgünlük: Bu çalışma inanç temelli Suriyeli mülteci topluluklardaki geri dönüş eğilimlerini göç literatürü ve Birleşmiş Milletler kriterleri bağlamında analiz etmektedir. Mevcut haliyle Türkiye’deki Suriyelilerin geri dönüşü, ülkede devam eden güvenlik problemleri, insani ihtiyaçların karşılanmaması ve Esad hükümetinin halen görevde olması nedeniyle ilgili literatür ve uluslararası kriterlerle uyuşmamaktadır.
BREXİT SÜRECİNİN EĞİTİM HAREKETLİLİĞİNE ETKİLERİ: ERASMUS’TAN TURİNG’E YENİ FIRSATLAR VE TEHDİTLER
Authors: ÖZEY Ezgi , ÖZÖZEN KAHRAMAN Selver
Published: September 2022

Amaç: Bu çalışmada Birleşik Krallık’ın (BK) Avrupa Birliği’nden (AB) ayrılma kararıyla birlikte AB’nin sınırlarını kıta sınırına çekerek ekonomik, sosyal ve politik açıdan daralma etkisi yaratan Brexit sürecinin genel olarak AB bağlantılı göçlere özelde ise Erasmus hareketliliğine olan etkileri ele alınmıştır. Erasmus Programı’nın nitelikli aktörlerinden biri olan BK’nın süreçten çekilmesinin etkileri yanında bu sürecin başlangıçta Türkiye’nin Erasmus hareketliliğini nasıl etkilediği ve gelecekte nasıl etkileyebileceğinin araştırılması çalışmanın amacını oluşturmaktadır. Yöntem: Bu çalışmada nitel araştırma yöntemlerinden durum çalışması deseni kullanılmıştır. Veri toplama aracı olarak ise resmi istatistiklere dayalı dokümanlardan yararlanılmıştır. Çalışma kapsamında üç farklı veri grubu kullanılmaktadır. Bunlar: (i) Avrupa Komisyonu yıllık raporlarından elde edilen 2014-2019 yıllarına ait BK’nın Erasmus öğrenci ve personel hareketliliği verileri, (ii) Ulusal Ajans ve Avrupa Komisyonu yıllık raporlarından elde edilen 2004-2019 yıllarına ait Türkiye’nin Erasmus öğrenci ve personel hareketliliği verileri ve (iii) BK’nın resmi internet sayfasından (Turing Scheme) elde edilen Turing Programı’nın işleyiş şemasına yönelik istatistiki verilerdir. Bulgular: AB bağlantılı hareketliliklerde önemli bir yeri olan Erasmus Programı, Brexit süreci boyunca tartışılan konulardan biridir. BK’nın programdan çekilmiş olmasının diğer program ülkeleri ve ülkemiz için bir kayıp olacağı açıktır. Her ne kadar BK ve Türkiye arasında çok yoğun bir hareketlilik olmasa da Brexit sonrası gündeme getirilen Turing Programı’nda Türkiye’ye verilen kontenjanların Erasmus’un çok gerisinde kalmış olması, Türkiye’nin bu süreçte ihmal edildiğini ve beklentilerin ülkemiz açısından karşılanamadığını göstermektedir.Özgünlük: Birçok ülke Erasmus hareketliliğinin hem eğitim sistemine hem de ülke ekonomisine yaptığı katkılardan yararlanabilmek için kıyasıya rekabet halindedir. Türkiye’nin de önemli aktörlerinden biri olduğu bu hareketlilikte ülkeler arasında yaşanan politik krizlerin ülkemiz üzerindeki olası sonuçlarının tartışılması oldukça kritik bir konudur. Özellikle ulusal literatür incelendiğinde Brexit sürecinin daha çok siyasi, ekonomik faktörler ve göç (sığınmacılar, serbest dolaşım) konusu üzerinden değerlendirildiği fakat sürecin eğitim hareketliliği üzerinde yaratacağı tehditlerin ve fırsatların gözden kaçırıldığı görülmektedir. Nitekim bu çalışmayla Brexit ve eğitim hareketliliği ile ilgili literatüre farklı bir bakış açısı kazandırılabilir.
Effects of thermal stratification and mixing on the vertical distribution of dissolved oxygen in aquaculture ponds
Authors: Wan Xiao , Jiang Shunyao , Xiong Qinxue , Yang Jun R. , Xia Sujing , Chen Qihang
Published: September 2022

Thermal stratification and mixing in aquaculture ponds can seriously affect the vertical distribution of dissolved oxygen (DO) and result in a lack of DO in ponds. Therefore, revealing the vertical distribution of DO in aquaculture ponds influenced by thermal stratification and mixing can provide a theoretical basis for aquaculture water management. Here, we explore the impacts of thermal stratification and mixing on the vertical distribution of DO in two aquaculture ponds under different weather conditions. The results showed that thermal stratification mainly occurs during the daytime, and mixing occurs at nighttime. Water thermal stratification appears 4 h after sunrise, while mixing occurs 1 h after nightfall. When the Richardson index is less than 0.25, the mixing direction is unstable. In the daytime, the vertical distribution of DO, chlorophyll a (Chl-a), and phytoplankton abundance varied with thermal stratification and mixing. The concentration of DO gradually dropped with increasing water depth during the nighttime. The concentration of DO was lowest in the early morning and peaked in the afternoon. Multiple regression analysis demonstrated that water temperature (WT), Chl-a, and phytoplankton abundance provided the best model for the vertical distribution of DO. Based on our results, DO regulation can provide important insights for aquaculture pond management.
The Most Common In-Hospital Causative Agent of Bladder Catheter-Associated Lower Urinary Tract Infection
Authors:   Universidad Autónoma de Guadalajara., Valdez Hamilton Miranda
Published: September 2022

Urinary tract infections are caused by an erroneous placement of catheters, This is because it is considered an invasive technique of very common hospital use, which will provide a great benefit to the patient and quite useful for the doctor. The identification in the different hospital centres of the correct technique has to be achieved to achieve an effective sterile placement and obtain a benefit rather than a harm to the patient. However, the fact of having to identify the correct techniques has shown certain deficiencies among health personnel who are in charge of these procedures. It is known that the placement of catheters by extraluminal route, has a higher incidence of infection because it is placed ascendingly and is the most common way to cause a urinary tract infection. In a large majority of infections, its causative agents are given by Gram-negative bacteria and with the appearance of resistance to antimicrobials, it has become a great concern on the part of health personnel. At the same time, it is necessary to recognize the need to indicate antimicrobial therapy when placing the catheter.
Reduce the Effort and Time in Calculating the Absenteeism Percentage of Students
Authors:   Northern Technical University, Iraq, Hasan Aga Manhal Mohammad Basher , Shihab Luay Abdulwahid ,   Department of Basic science – college of Nursing ,University of Basrah, Iraq
Published: September 2022

This study started from some of the problems that took from our institution a lot of time to solve, this study included two parts, and the first part is Image discrimination problems are usually difficult to solve using unprocessed data. To improve the discrimination process Characteristic extraction is often needed to represent data in a space of distinction. Pattern recognition aims to find or recognize specific patterns or structures in digital images (signal). To identify a pattern or an object in an image, you must first obtaining direct preliminary and statistical information about the image that must be digital in order to be able to deal with it by computer. The information in the image must also be classified to facilitate subsequent operations on the image, such as Debriefing The second part is to calculate the absences of students with an electronic system based on two languages where VB.Net language was adopted to accomplish the program interfaces in addition to the special code to find the percentage of absences, SQL was adopted for the purpose of creating a database in the program and storing data. The process of finding a mechanism to link the VB.Net program with the Internet for sending an e-mail message to the person concerned with the program (the student) for informing the percentage of absences in the study materials when exceeded the ratio approved in the program. The program has also been linked to a local network to be used on more than one computer at the same time and on a single database.
Transperineal Freehand US/MRI Fusion Target Prostate Biopsy using the Esaote MylabTM9 System: A Step by Step Guide
Authors:   Medical Director in Urology at the Western Hospital Unit “San Pio” in Castellaneta,Via del Mercato,1, Castellaneta, Italy and Resident of Urology at the University of Bari at the Azienda Ospedaliero-Universitaria Policlinico di Bari, Piazza Giulio Cesare, 11, Bari, Italy, Rinaldi Marco , Di Lena Sebastiano ,   Chief of Urology at the Western Hospital Unit “San Pio” in Castellaneta, Via del Mercato,1, Castellaneta, Italy
Published: September 2022

Objective: To document a step-by-step guide of transperineal Freehand US/MRI fusion target prostate biopsy using the Esaote MyLabTM9 System. Setting: “San Pio” Hospital of Castellaneta, Italy. Patients: The patients undergoing this procedure had a suspicion of prostate cancer based on a mpMRI of the prostate. Results: No major complications were seen during and after the biopsy, and the patients were discharged 30 minutes-1 hour after the procedure. Conclusions: Fusion-targeted biopsy has proven to be better than random technique for both biopsy-naïve and previous negative biopsy [1]. With a standardized step-by-step approach the procedure can give good detection rate results with little or without discomfort for the patients and with short operating times.
Electronic Submission and Utilization of CDISC Standardized Clinical Study Data in Japan
Authors: Ando Yuki
Published: September 2022

In Japan, the submission of subject-level electronic clinical study data for new drug applications began on October 1, 2016 and included a transitional period that expired on March 31, 2020. Currently, most new drug applications (NDAs) require the submission of electronic clinical study data, which are considered important to provide information about a drug at the review and are required by the Pharmaceuticals and Medical Devices Agency (PMDA). Standardization of submitted electronic clinical study data is essential to efficient review, using data analyses for applications of various drugs submitted by multiple companies with limited review time and human resources. For most clinical trials, the PMDA requires study data to be submitted in accordance with CDISC standards.This paper provides an overview of the advanced review with electronic data project and the current state of electronic data submission in Japan, as well as in terms of future expectations for the data standards, as based upon the experiences of receiving and utilizing CDISC-compliant clinical study data in the PMDA.
Assessment of the influence of weather factors on the quantitative indicators of sweet cherry fruits by Ridge regression
Authors: IVANOVA IRYNA , SERDYUK MARYNA , MALKINA VIRA , TYMOSHCHUK TETYANA , SHKINDER-BARMINA ANNA
Published: September 2022

Sweet cherries are a favourite stone crop among consumers of fruit products. At present, the demand for sweet cherries is growing, which encourages the expansion of the varietal range of crops with different ripening periods. The purpose of this study was to develop a mathematical model for predicting the formation of fruit and sweet cherry pyrene mass depending on weather factors and varietal characteristics. The study was conducted during 2008–2019 in the conditions of the Southern Steppe zone of Ukraine on 33 varieties of sweet cherries of early, medium, and late ripening periods. The average mass of the sweet cherry fruit over the years of research was 8.41 g, and the average mass of the pyrene was 0.56 g. Late-ripening sweet cherry varieties had the best fruit mass (7.27–12.18 g). According to the maximum average mass of the fruit, the varieties Kazka, Dilema, and Kosmichna were distinguished. Sweet Erlise, Pervistok, Melitopol black and Krupnoplidna varieties had the lowest pyrene mass in sweet cherry fruits. In the group of early ripening, the best ratio of pyrene to fruit pulp was found in the Kazka variety, in medium-ripening varieties – Cordia, Perviystok, and Orion, in late-ripening varieties – Udivitelna, Krupnoplidna, and Prazdnichna.The smallest variability in sweet cherry fruit mass in the group of early-ripening varieties was detected in Sweet Erlise, in mid-ripening – Temp, and in late-ripening – Regina, while in pyrene mass – Rubinova Rannia, Vynka and Regina, respectively. Weather conditions had a dominant influence on the formation of fruit mass for all sweet cherry varieties under study, and varietal characteristics had a dominant effect on pyrene mass. The maximum influence on the formation of sweet cherry fruit mass of early varieties was provided by the indicator – the number of days with precipitation in May exceeding 1 mm, and for medium and late ripening varieties – the average monthly amount of precipitation in June. Decisive importance for the formation of pyrene mass in sweet cherry fruits of early ripening varieties was the average monthly amount of precipitation in May, in the middle ripening period – the average monthly amount of precipitation in June, in the late ripening period – the number of days with precipitation exceeding 1 mm in May.
Trauma renal grado IV: trauma cerrado de abdomen
Authors: Arias-Martínez Kevin , Caracheo-Hernández Carolina , Acosta-Martínez Elissa Estefanía
Published: September 2022

Descripción del caso clínico: Nuestro paciente de 16 años presentó un cuadro de 48 horas de evolución, al sufrir caída de una bicicleta en movimiento impactando sobre su costado izquierdo contra el pavimento. La tomografía de abdomen revela presencia de hematoma perirrenal en expansión. Se realiza laparotomía exploratoria, observando hemoperitoneo y hematoma renal izquierdo, lesión del hilio renal con sangrado activo y hematoma en expansión. Se decide realizar nefrectomía izquierda.
Relevancia: Los traumatismos renales son las lesiones genitourinarias más frecuentes. Cerca del 90% son traumatismos cerrados.
Implicación clínica: Aunque la mayoría de los traumas renales son limitados y rara causa de muerte, si no se diagnostican y tratan adecuadamente ocasionan una elevada morbilidad por las complicaciones tardías: hipertensión arterial, hidronefrosis, pseudonefrosis traumática, atrofia y litiasis renales.
Conclusiones: Los pacientes jóvenes, sufren mayor riesgo de lesiones abdominales.
Complicaciones posquirúrgicas en cistectomías radicales a 30 días: factores relacionados y uso de la escala de APGAR quirúrgico para su predicción
Authors: González-Sánchez Benjamín Casimiro , Garza-Gangemi Adrián Mauricio , Martínez-Silva Luis Roberto , Delgado-Martínez Guillermo Hernán , Castillo-Burelo Larissa , Cruz-Gebhardt Erika Denisse , Castillejos-Molina Ricardo Alonso
Published: September 2022

Objective: Bladder cancer represents the seventh most common cancer with highly variable morbidity and mortality due to detection, treatment and follow-up strategies, with radical cystectomy (RC) being the treatment that offers the best oncological control. A morbidity rate between 30-93% has been reported at 30 days, and mortality greater than 8%. This variability is due to the scarcity of standardized reports using scales such as Clavien-Dindo (CD). Due to the little evidence of publications on complications associated with RC, we decided to make a standardized report of these, using the CD scale of the RCs performed in our hospital, with the goal of finding out the incidence and real severity of these.
Materials and methods: A retrospective analysis was made of a prospectively maintained database of RCs performed in our center between 1994 and 2019. All patients over 18 years of age who underwent RC during the study period were included, and all patients with incomplete documentation of the immediate 30 day-postoperative were excluded. Descriptive statistics were used for data presentation. The Kolmogorov-Smirnov test was used to determine the data distribution. An inferential mean comparison analysis was performed using the Student's t-test for variables with normal distribution, and non-parametric tests (Mann–Whitney U-test) for those with non-normal distribution.
Results: The mean age of the study population was 61.16 years (SD 10.1). Patients without major complications had a BMI 2.45 kg/m2 lower compared to patients with major complications (95% CI -4.7 to -0.18). Bleeding and surgical time, as well as type of derivation, were not significantly associated with major complications.
Study limitations: It was a retrospective study, so the SAS could not be calculated for the entire population. Also, it was a small cohort of patients in a tertiary care center with a restricted number of hospital beds, which considerably reduces the statistical power of the study to find low-frequency events (mortality). Extending the follow-up to more than 30 days could modify the incidence of complications.
Originality: Our series is the first to use a standardized system (Clavien-Dindo scale) to report postoperative complications in patients undergoing RC in Mexico.
Conclusions: RC continues to be one of the surgeries with the highest morbidity. The use of standardized scales for reporting complications associated with RC would allow us to establish prevention strategies and establish homogeneous surveillance criteria with other specialties.
Evolución y optimización con los avances en suturas y energía de procedimientos urológicos laparoscópicos en Puebla
Authors: Arroyo-Kuribreña Jose Carlos , Soto-Vega Elena
Published: September 2022

Objetivo: Analizar la evolución de la cirugía laparoscópica y la influencia de los elementos técnicos como la implementación de pinza bipolar y sutura barbada en el éxito quirúrgico.
Metodología: Se revisaron en forma retrospectiva todos los expedientes y videos de procedimientos laparoscópicos realizados por un cirujano y se realizó estadística descriptiva buscando diferencias en el tiempo quirúrgico y el sangrado.
Resultados: Se analizaron 140 cirugías, el 89.3% en instituciones particulares. Las cirugías analizadas fueron prostatectomía radical laparoscópica (42.8%), nefrectomía radical (33.5%), nefrectomía parcial (5.7%) y otras. Con tiempo quirúrgico promedio de 130 minutos, y sangrado promedio de 430 ml, se reportaron solo 4 complicaciones graves (2.1%) y una tasa de mortalidad de 0.7%. La tasa de conversión a cirugía abierta fue del 1.4%. La estancia hospitalaria fue en promedio 2.4 días. El uso de pinza bipolar y la sutura barbada disminuyo el tiempo operatorio y sangrado.
Limitaciones del estudio: Debido a que se trata de la experiencia de un solo cirujano, procedimientos diversos y la evolución en el tiempo, se debe realizar un estudio multicéntrico comparativo para confirmar los resultados.
Originalidad: En México no se ha realizado un análisis del uso de tecnología en la cirugía laparoscópica en urología.
Conclusiones: Se reporta una evolución individual en la técnica y experiencia que ha permitido optimizar los tiempos quirúrgicos y los resultados postoperatorios que se asocian al uso de tecnología para la disección y el uso de suturas barbadas que mejoran los resultados.
Da dialetologia geral à dialetologia contatual
Authors: Sanches Romário Duarte
Published: September 2022

Este artigo busca apresentar a ideia de uma Dialetologia Geral e suas ramificações, sobretudo da Dialetologia Contatual aplicada no Brasil. Para embasamento teórico, têm-se as discussões de Preston (1989), Menendéz (1990), Chambers e Trudgill (1994), Fisiak (1995), Thun e Altenhofen (2016), Heeringa e Prokić (2018), entre outros. Por meio do levantamento bibliográfico, constatou-se que a Dialetologia tradicional do século XIX adquiriu novos modelos para investigar a variação linguística. Hoje é possível falar em uma Dialetologia Geral (DG) que engloba várias vertentes, isto é, dentro do escopo da DG pode-se mencionar a Dialetologia Medieval/Filológica, a Dialetologia Estrutural, a Dialetologia Gerativa, a Dialetologia Social, a Dialetologia Perceptual, a Dialetologia Contatual e a Dialetologia Computacional. No Brasil, com base nos trabalhos geolinguísticos desenvolvidos nos últimos 20 anos, a Dialetologia Social é a mais aplicada; no entanto, percebe-se o aumento gradativo de pesquisas voltadas para a Dialetologia Contatual, sustentadas pelo modelo de Dialetologia Pluridimensional e Relacional.
Geolinguística: desafios da metodologia pluridimensional
Authors: Carlos Valeska Gracioso
Published: September 2022

Este trabalho apresenta algumas considerações metodológicas aplicadas em uma pesquisa de doutorado, que visou a descrição das variedades linguísticas da língua portuguesa falada na região de fronteira entre Brasil e Paraguai, mais especificamente, no estado do Paraná e o departamento del Alto Paraná, e a consequente produção de cartas linguísticas de caráter contatual e topodinâmico da área investigada. Em termos metodológicos, seguindo os pressupostos da Dialetologia Pluridimensional, foram consideradas as oito dimensões propostas por Thun (1998), a saber: diatópica, diastrática, diassexual, diageracional, a diatópico-cinética, dialingual, diafásica e diarreferencial. A utilização dessas dimensões interfere diretamente na escolha da rede de pontos, na definição do perfil do informante, no tipo de questionário e, até mesmo, nos dados para a ficha do informante. Só foi possível considerar as oito dimensões devido ao tipo de trabalho proposto, à região que proporciona uma gama de diferentes contatos linguísticos e, sobretudo, às migrações no Oeste do Paraná e às imigrações ao Paraguai. A pesquisa buscou compreender o comportamento linguístico, nas suas diferentes variedades, diante de dimensões de ordem linguística, espacial e social.
CONTRIBUIÇÕES DA EPIDEMIOLOGIA BASEADA EM ÁGUAS RESIDUAIS PARA VIGILÂNCIA EM SAÚDE PÚBLICA
Authors: Marques Paulo Ricardo Conceição , Dolabella Silvio Santana , Jain Sona , Barbosa Ana Andréa Teixeira
Published: September 2022

Introdução: A vigilância em saúde planeja e executa ações que visam a eliminação, controle e prevenção dos riscos à saúde dos cidadãos. Neste contexto, a epidemiologia baseada em águas residuais promete revolucionar as técnicas de monitoramento de doenças através da detecção de biomarcadores em amostras de esgotos, o que norteará decisões e intervenções imediatas de prevenção, controle e tratamento a serem implementadas pelos órgãos de saúde. Objetivo: Identificar e discutir as vantagens, desafios e contribuições da epidemiologia baseada em águas residuais no monitoramento de doenças e orientação das ações de vigilância em saúde pública. Métodos: Através da análise pormenorizada de artigos científicos, com informações relevantes sobre entrelaces da epidemiologia baseada em águas residuais e a vigilância em saúde, obtivemos uma ideia precisa sobre o estado atual dos conhecimentos, lacunas e contribuições para o desenvolvimento científico dessa abordagem epidemiológica. Resultados: A análise de biomarcadores presentes na excreção humana tem proporcionado a obtenção de informações sobre estimativas populacionais, alertas precoces de surtos de doenças infecciosas como a covid-19, consumo de medicamentos e drogas, adesão às terapias farmacológicas prescritas, resistência antimicrobiana, exposição a substâncias tóxicas e poluentes, segurança alimentar e rastreamento de câncer na população. Conclusão: Apesar dessa abordagem avaliar as condições de vida e saúde da população de forma rápida, econômica, padronizada e eficiente, a sua expansão e inserção aos programas de vigilância, principalmente em países em desenvolvimento, depende de investimentos que garantam a universalização do saneamento básico, desenvolvimento e aplicação de novos biomarcadores no monitoramento de águas residuais e profissionais capacitados.
DEFICIÊNCIAS E DESAFIOS DO PLANEJAMENTO TERRITORIAL DE ÁREAS RURAIS NO BRASIL
Authors: Rodrigues Ribeiro dos Santos Mariana , Lima Ranieri Victor Eduardo
Published: September 2022

É necessário que as áreas rurais sejam pensadas e planejadas de forma integrada às áreas urbanas, uma vez que há uma relação de trocas de matéria e energia constante entre elas e que as tornam dependentes uma da outra. Entretanto, esta ainda aparenta ser uma prática deficiente em boa parte dos municípios brasileiros. Este trabalho busca identificar as deficiências e desafios quanto ao planejamento territorial de áreas rurais no Brasil e dar contribuições ao debate. É dada atenção ao Plano Diretor municipal como instrumento de planejamento territorial e à sua esperada relação com o rural e com instrumentos de planejamento ambiental. Constata-se uma distancia entre a teoria e a prática, ainda que haja instrumentos para tal, indicando a necessidade de maior integração entre estes, entre as escalas e recortes de trabalho, e entre as perspectivas de planejamento urbana e ambiental, reforçando a importância da visão regional neste processo.
TERRITÓRIO SUDOESTE PAULISTA: ENTRE CONFLITOS, RELAÇÕES DE PODER E IDENTIDADES – NOTAS DE UMA PESQUISA
Authors: Antunes Junior Wolney Felippe
Published: September 2022

A importância deste relato de experiência ganha tamanho e notoriedade quando - em meio a coleta de dados para uma pesquisa de mestrado sobre políticas públicas de desenvolvimento territorial e seus arranjos institucionais – vem à tona uma série de elementos que estruturam o entendimento dos territórios, que são os seus conflitos, as relações de poder e as identidades. Neste caso, são questões referentes ao território Sudoeste Paulista, que se situa entre o Norte Pioneiro do Paraná e o Vale do Ribeira. O objetivo, portanto, deste texto é apresentar (e propor reflexões) sobre os elementos que moldam a dinâmica territorial do Sudoeste Paulista. Especificamente, a partir dos casos ilustrados pelos municípios de Riversul, Itaberá, Ribeirão Branco e Ribeirão Grande.
Strategy Under Uncertainty: A Sectoral Analysis of Strategic Posture and Performance in the Turkish Logistics Sector
Authors: YILDIRIM ÖZMUTLU Saniye , CAN Esin
Published: September 2022

In this study, the effect of environmental conditions on firm performance in the Turkish logistics sector, in the context of the presence of the mediator role of the strategic posture and the interaction between the variables were investigated. The data set covering the Marmara region was expanded to cover all Turkey, and the hypotheses in the research model created by extending the period were retested and the study was repeated. The sector was analyzed on a country basis by reevaluating the findings comparatively. In the research, a survey was applied to 475 people working in managerial positions in firm operating in the Turkish logistics sector. Empirical evidence regarding the mediating role of strategic posture was obtained from this study. As a result, it was determined how important it is for Turkish logistics companies to have a strategic posture, and it is a very important complement in terms of improving performance. In addition, the necessity for the companies examined within the scope of the study to make strategic choices in line with the impact of the environmental conditions was revealed.
Contributions of meteorology and anthropogenic emissions to the trends in winter PM2.5 in eastern China 2013–2018
Authors: Wu Yanxing , Liu Run , Li Yanzi , Dong Junjie , Huang Zhijiong , Zheng Junyu , Liu Shaw Chen
Published: September 2022

Abstract. Multiple linear regression (MLR) models are used to
assess the contributions of meteorology/climate and anthropogenic emission
control to linear trends of PM2.5 concentration during the period
2013–2018 in three regions in eastern China, namely Beijing–Tianjin–Hebei
(BTH), the Yangtze River Delta (YRD), and the Pearl River Delta (PRD). We find that
quantitative contributions to the linear trend of PM2.5 derived based
on MLR results alone are not credible because a good correlation in the MLR
analysis does not imply any causal relationship. As an alternative, we
propose that the correlation coefficient should be interpreted as the
maximum possible contribution of the independent variable to the dependent
variable and the residual should be interpreted as the minimum contribution
of all other independent variables. Under the new interpretation, the
previous MLR results become self-consistent. We also find that the results
of a short-term (2013–2018) analysis are significantly different from those
of a long-term (1985–2018) analysis for the period 2013–2018 in which they overlap,
indicating that MLR results depend critically on the length of time
analyzed. The long-term analysis renders a more precise assessment because
of additional constraints provided by the long-term data. We therefore
suggest that the best estimates of the contributions of emissions and
non-emission processes (including meteorology/climate) to the linear trend
in PM2.5 during 2013–2018 are those from the long-term analyses: i.e.,
emission <51 % and non-emission >49 % for BTH,
emission <44 % and non-emission >56 % for YRD, and
emission <88 % and non-emission >12 % for PRD.