bluuebunny/crossref_metadata_2025 huggingface dataset:
Predicting Erosion Damage in a Centrifugal Fan
Authors: Ghenaiet Adel
Published: June 2024

Erosion damage can occur in fans and blowers during industrial processes, cooling, and mine ventilation. This study focuses on investigating erosion caused by particulate air flows in a centrifugal fan with forward-inclined blades. This type of fan is particularly vulnerable to erosion due to its radial flow component and flow recirculation. The flow field was solved separately, and the data transferred to the particle trajectory and erosion code. This in-house code implements the Lagrangian approach and the random walk algorithm, including statistical descriptions of particle sizes, release positions, and restitution factors. The study involved two types of dust particles, with a concentration between 100 and 500 μg/m3: The first type is the Saharan (North Africa) dust, which has a finer size between 0.1 and 100 microns. The second type is the Coarse Arizona Road Dust, also known as AC-coarse dust, which has a larger size ranging from 1 to 200 microns. The complex flow conditions within the impeller and scroll, as well as the concentration and size distribution of particles, are shown to affect the paths, impact conditions, and erosion patterns. The outer wall of the scroll is most heavily eroded due to high-impact velocities by particles exiting the impeller. Erosion is more pronounced on the pressure side of the full blades compared to the splitters and casing plate. The large non-uniformities of erosion patterns indicate a strong dependence with the blade position around the scroll. Therefore, the computed eroded mass is cumulated and averaged for all the surfaces of components. These results provide useful insights for monitoring erosion wear in centrifugal fans and selecting appropriate coatings to extend the lifespan.
Autonomous Vehicle Safety through the SIFT Method: A Conceptual Analysis
Authors: Anshari Muhammad , Almunawar Mohammad Nabil , Masri Masairol , Fitriyani Norma Latif , Syafrudin Muhammad
Published: June 2024

This study aims to provide a conceptual analysis of the dynamic transformations occurring in an autonomous vehicle (AV), placing a specific emphasis on the safety implications for pedestrians and passengers. AV, also known as self-driving automobiles, are positioned as potential disruptors in the contemporary transportation landscape, offering heightened safety and improved traffic efficiency. Despite these promises, the intricate nature of road scenarios and the looming specter of misinformation pose challenges that can compromise the efficacy of AV decision-making. A crucial aspect of the proposed verification process is the incorporation of the stop, investigate the source, find better coverage, trace claims, quotes, and media to the original context (SIFT) method. The SIFT method, originally designed to combat misinformation, emerges as a valuable mechanism for enhancing AV safety by ensuring the accuracy and reliability of information influencing autonomous decision-making processes.
Key Performance Indicators Predictive of Success in Soccer: A Comprehensive Analysis of the Greek Soccer League
Authors: Stafylidis Andreas , Mandroukas Athanasios , Michailidis Yiannis , Vardakis Lazaros , Metaxas Ioannis , Kyranoudis Angelos E. , Metaxas Thomas I.
Published: June 2024

Previous research emphasizes the significance of key performance metrics in determining match outcomes. The purpose of this study is to enhance the understanding of success in professional soccer by analyzing the relationship between match outcomes (win, lose, draw) and various Performance Indicators extracted from the Greek soccer league, as well as to develop a regression model of success in soccer. The sample consisted of all 91 matches from the first round of the 2020–2021 season of the Greek Football League. Utilizing Kruskal–Wallis tests, significant differences were found in goals scored, shots, and shots on target, ball possession, passing metrics, touches in the penalty area, and average shot distance (p < 0.05), with winning teams having demonstrated superior performance metrics. Moreover, winning teams engaged more in positional attacks and counterattacks with shots (p < 0.05). The binary logistic regression model applied to predict match outcomes identified shots on target, counterattacks, passes metrics, offensive duels and set pieces (penalties, free kicks) as key factors influencing the likelihood of winning (p < 0.05). These findings collectively highlight the importance of effective offensive play, including goal scoring, shooting accuracy, and ball possession, in determining the outcomes of soccer matches, with the regression model offering a nuanced understanding of these relationships.
Marine Radar Oil Spill Detection Method Based on YOLOv8 and SA_PSO
Authors: Xu Jin , Huang Yuanyuan , Dong Haihui , Chu Lilin , Yang Yuqiang , Li Zheng , Qian Sihan , Cheng Min , Li Bo , Liu Peng , Wu Jianning
Published: June 2024

In the midst of a rapidly evolving economic landscape, the global demand for oil is steadily escalating. This increased demand has fueled marine extraction and maritime transportation of oil, resulting in a consequential and uneven surge in maritime oil spills. Characterized by their abrupt onset, rapid pollution dissemination, prolonged harm, and challenges in short-term containment, oil spill accidents pose significant economic and environmental threats. Consequently, it is imperative to adopt effective and reliable methods for timely detection of oil spills to minimize the damage inflicted by such incidents. Leveraging the YOLO deep learning network, this paper introduces a methodology for the automated detection of oil spill targets. The experimental data pre-processing incorporated denoise, grayscale modification, and contrast boost. Subsequently, realistic radar oil spill images were employed as extensive training samples in the YOLOv8 network model. The trained detection model demonstrated rapid and precise identification of valid oil spill regions. Ultimately, the oil films within the identified spill regions were extracted utilizing the simulated annealing particle swarm optimization (SA-PSO) algorithm. The proposed method for offshore oil spill survey presented here can offer immediate and valid data support for regular patrols and emergency reaction efforts.
The Evolving Landscape of Spanish Language Representation in U.S. Media: From Overt to Covert Discrimination
Authors: Parker Grace A. , Botek Maia , Pascual y Cabo Diego
Published: June 2024

Despite the continuously expanding presence of Spanish-speaking communities in the United States, media representation of the Spanish language and that of its speakers has remained relatively scarce. At present, however, a growing interest in reaching and cashing in on this influential consumer group is forcing significant changes in the mass media communication landscape. Not only are an increasing number of movies and TV shows working with more diverse casts (ethnically, culturally, linguistically, etc.), but there also seems to be a heightened presence of Latinx characters in leading or supporting roles. This tendency, however, does not necessarily mean that mainstream media is becoming more inclusive and less anglocentric. In fact, a careful look at the storylines of individuals who are perceived to be Spanish speakers will reveal that they mostly portray stereotypical roles and behaviors. When their stories are told, they are all too often infused with unwarranted messages that portray Latinxs as lazy, unskilled, unintelligible in speech, hypersexual, or simply too ‘foreign’ to fit in. Whether overtly or covertly expressed, the negative impact of these persistent transgressions has the potential to shape real-world ideologies, attitudes, and prejudices. This paper adopts a critical raciolinguistic perspective, which underscores the co-naturalization of language and race, to highlight the role of media in reinforcing discrimination against the Spanish language and its speakers. In our analysis of six recently popularized TV shows (i.e., East Los High, Family Guy, Gentefied, Jane the Virgin, One Day at a Time, and That ‘70s Show), we examine the perpetuation of racialized stereotypes toward Latinx characters’ linguistic practices with regard to (i) the environment in which they exist, (ii) their mannerisms, (iii) speech patterns, and (iv) interactions with other characters. We demonstrate how these shows’ blending of seemingly harmless linguistic ideologies with stereotypical and sensationalized representations grounded in colonial hierarchies reproduces hegemonic interests, perpetuates social inequalities, and places racialized Spanish speakers at a disadvantage.
Optimal Strategy of Unreliable Flexible Production System Using Information System
Authors: Rezig Sadok , Turki Sadok , Chakroun Ayoub , Rezg Nidhal
Published: June 2024

Background: Optimization approaches and a models can be applied for critical production systems that experience equipment failure, repair delays and product quality control in order to maximize the total profit. We can cite, as an example, flexible manufacturing systems. Methods: Our methodology involves developing a decision model integrated with an information system to coordinate various system operations, ensuring timely response to customer requests. The module of the information system is provided to optimally manage the production flow and parts ordering according to machine availability. The objective is to determine the optimal order thresholds of part batches that maximize the total profit. Results: Numerical results are provided to analyze the influence of system reliability and uncertainty on decision variables, offering insights into the system’s performance and robustness. By using our method, the advancement of the flexible production systems is carried out by addressing key operational challenges and optimizing production processes for enhanced efficiency and profitability. Conclusions: To achieve this, an optimization algorithm is employed to identify optimal solutions that enhance profitability.
Incorporation of Anions into Anodic Alumina—A New Track in Cr(VI) Anodizing Substitution?
Authors: Tomczyk Katarzyna , Stępniowski Wojciech J.
Published: June 2024

Aluminum technical alloys are well known for their outstanding mechanical properties, especially after heat treatment. However, quenching and aging, which improve the mechanical properties, by the formation of Cu-rich zones and phases that are coherent with the matrix and block the dislocation motion, cause uneven distribution of the elements in the alloy and consequently make it prone to corrosion. One method providing satisfactory corrosion protection of aluminum alloys is anodizing. On an industrial scale, it is usually carried out in electrolytes containing chromates that were found to be cancerogenic and toxic. Therefore, much effort has been undertaken to find substitutions. Currently, there are many Cr(VI)-free substitutes like tartaric–sulfuric acid anodizing or citric–sulfuric acid anodizing. Despite using such approaches even on the industrial scale, Cr(VI)-based anodizing still seems to be superior; therefore, there is an urge to find more complex but more effective approaches in anodizing. The incorporation of anions into anodic alumina from the electrolytes is a commonly known effect. Researchers used this phenomenon to entrap various other anions and organic compounds into anodic alumina to change their properties. In this review paper, the impact of the incorporation of various corrosion inhibitors into anodic alumina on the corrosion performance of the alloys is discussed. It is shown that Mo compounds are promising, especially when combined with organic acids.
Preparation and Performance Study of SiC-Reinforced Fe-Based Wear-Resistant Composite Grinding Media
Authors: Yang Kun , Zhou Yongmin
Published: June 2024

During industrial and laboratory processes involving material grinding, the grinding media endure prolonged high-collision and friction environments, resulting in substantial wear. Consequently, this study adopts the hot-pressing sintering technique in powder metallurgy to prepare SiC-reinforced Fe-based wear-resistant composite grinding media, aiming to increase wear performance. For this purpose, Fe with 10 wt% SiC powders were milled for the fabrication of the composite. Then, sintering was performed by hot press at 1100 °C in a furnace. Scanning electron microscopy (SEM) and X-ray diffraction were employed to investigate the microstructures and phase of SiC-reinforced Fe-based matrix composite. Subsequently, comparative performance evaluations of the newly developed grinding media and traditional chromium-based media were conducted in terms of wear rate and grinding efficiency. The wear resistance tests revealed that the SiC-reinforced composite media displayed significantly superior wear resistance across various abrasives compared to the chromium-containing alternatives. Specifically, the composite media achieved a wear rate reduction of 2.9 times against standard sand over 1 h, and 2.3 and 2.4 times against sandstone and iron slag, respectively. Moreover, extended grinding for 3 hours further enhanced these reductions to 3.1, 2.4, and 2.7 times, respectively. Additionally, efficiency assessments indicated that at a 1:1 material ratio, the composite media outperformed the chromium-containing media in grinding efficiency by 7.5%, 12.5%, and 10.3% for standard sand, sandstone, and iron slag, respectively. Further increasing the material ratio to 3:1 resulted in efficiency improvements of 7.4%, 17.5%, and 11.3%, correspondingly.
Effects of Low-Temperature Heat Treatment on Mechanical and Thermophysical Properties of Cu-10Sn Alloys Fabricated by Laser Powder Bed Fusion
Authors: Honu Edem , Emanet Selami , Chen Yehong , Zeng Congyuan , Mensah Patrick
Published: June 2024

This study investigated the impact of low-temperature heat treatments on the mechanical and thermophysical properties of Cu-10Sn alloys fabricated by a laser powder bed fusion (LPBF) additive manufacturing (AM) process. The microstructure, phase structure, and mechanical and thermal properties of the LPBF Cu-10Sn samples were comparatively investigated under both the as-fabricated (AF) condition and after low-temperature heat treatments at 140, 180, 220, 260, and 300 °C. The results showed that the low-temperature heat treatments did not significantly affect the phase and grain structures of the Cu-10Sn alloys. Both pre- and post-treatment samples displayed consistent grain sizes, with no obvious X-ray diffraction angle shift for the α phase, indicating that atom diffusion of the Sn element is beyond the detection resolution of X-ray diffractometers (XRD). However, the 180 °C heat-treated sample exhibited the highest hardness, while the AF samples had the lowest hardness, which was most likely due to the generation of precipitates according to thermodynamics modeling. Heat-treated samples also displayed higher thermal diffusivity values than their AF counterpart. The AF sample had the longest lifetime of ~0.19 nanoseconds (ns) in the positron annihilation lifetime spectroscopy (PALS) test, indicating the presence of the most atomic-level defects.
Study of Coating Growth Direction of 6061 Aluminum Alloy in Soft Spark Discharge of Plasma Electrolytic Oxidation
Authors: Wang Wenqiang , Yang Yifeng , Liu Cancan , Chen Bo , Chen Xuanyu , Wang Hao , Tong Rui , Zhou Shiquan
Published: June 2024

Conventional plasma electrolytic oxidation treatments produce oxide coatings with micron-scale discharge pores, resulting in insulation and wear and corrosion resistance far below that expected of highly dense Al2O3 coatings. The introduction of cathodic polarization during the plasma electrolytic oxidation process, especially when the applied cathode-to-anode current ratio (Rpn) is greater than 1, triggers a unique plasma discharge phenomenon known as “soft sparking”. The soft spark discharge mode significantly improves the densification of the anode ceramic layer and facilitates the formation of the high-temperature α-Al2O3 phase within the coating. Although the soft spark discharge phenomenon has been known for a long time, the growth behavior of the coating under its discharge mode still needs to be studied and improved. In this paper, the growth behavior of the coating before and after soft spark discharge is investigated with the help of the micro-morphology, phase composition and element distribution of a homemade fixture. The results show that the ceramic layer grows mainly along the oxide–electrolyte direction before the soft spark discharge transformation; after the soft spark discharge, the ceramic layer grows along the oxide–substrate direction. It was also unexpectedly found that, under soft spark discharge, the silicon element only exists on the outside of the coating, which is caused by the large size and slow migration of SiO32−, which can only enter the ceramic layer and participate in the reaction through the discharge channel generated by the strong discharge. In addition, it was also found that the relative phase content of α-Al2O3 in the coating increased from 0.487 to 0.634 after 10 min of rotary spark discharge, which is an increase of 30.2% compared with that before the soft spark discharge transition. On the other hand, the relative phase content of α-Al2O3 in the coating decreased from 0.487 to 0.313 after 20 min of transfer spark discharge, which was a 55.6% decrease compared to that before the soft spark discharge transformation.
Wood Polymer Composite Based on Poly-3-hydroxybutyrate-3-hydroxyvalerate (PHBV) and Wood Flour—The Process Optimization of the Products
Authors: Frącz Wiesław , Pacana Andrzej , Siwiec Dominika , Janowski Grzegorz , Bąk Łukasz , Szawara Paulina
Published: June 2024

This study involved the optimization of the molded pieces manufacturing process from a poly-3-hydroxybutyrate-co-3-hydroxyvalerate biocomposite containing 30% wood flour by mass. The amount of wood flour and preliminary processing parameters were determined on the basis of preliminary tests. The aim of the optimization was to find the configuration of important parameters of the injection process to obtain molded pieces of good quality, in terms of aesthetics, dimensions, and mechanical properties. The products tested for quality were dog bone specimens. The biocomposite was produced using a single-screw extruder, whereas molded pieces were made using an injection molding process. The Taguchi method was applied to optimize the injection molding parameters, which determine the products quality. Control factors were selected at three levels. The L27 orthogonal plan was used. For each set of input parameters from this plan, four processing tests were performed. The sample weight, shrinkage, elongation at break, tensile strength, and Young’s modulus were selected to assess the quality of the molded parts. As a result of the research, the processing parameters of the tested biocomposite were determined, enabling the production of good-quality molded pieces. No common parameter configuration was found for different optimization criteria. Further research should focus on finding a different range of technological parameters. At the same time, it was found that the range of processing parameters of the produced biocomposite, especially processing temperature, made it possible to use it in the Wood Polymer Composites segment.
Frictional Properties of Soaps with the Addition of Ground Hazelnut Shells
Authors: Mazur Jacek , Wójcik Monika , Różyło Renata , Sobczak Paweł , Panasiewicz Marian , Obidziński Sławomir
Published: June 2024

The search for new technologies and related new biological materials for use in the cosmetics industry requires many studies and analyses of not only chemical but also physical properties. This study attempts to assess the properties of soap produced with the addition of crushed hazelnut shells. This additive is intended to improve the friction properties of the soap, which in turn enhances the quality of removing impurities from the skin. Friction tests for wet and dry skin were performed on an appropriately designed measuring station using the Texture Analyser XT plus device. The obtained results indicate an increase in dynamic friction value compared to the control sample. This work proposes an unconventional use of ground hazelnut shells as one of the additives in soap production to improve its quality.
Preparation, Physicochemical, and Cyto- and Genotoxic Characterisation of Polysaccharide Composites Containing Carbon Quantum Dots
Authors: Szczepankowska Joanna , Woszczak Liliana , Khachatryan Gohar , Khachatryan Karen , Krystyjan Magdalena , Grzesiakowska-Dul Anna , Kuchta-Gładysz Marta , Wojciechowska-Puchałka Joanna , Hovhannisyan Armen , Krzan Marcel
Published: June 2024

Rapid industrial growth is associated with an increase in the production of environmentally harmful waste. A potential solution to significantly reduce pollution is to replace current synthetic materials with readily biodegradable plastics. Moreover, to meet the demands of technological advancements, it is essential to develop materials with unprecedented properties to enhance their functionality. Polysaccharide composites demonstrate significant potential in this regard. Polysaccharides possess exceptional film-forming abilities and are safe for human use, biodegradable, widely available, and easily modifiable. Unfortunately, polysaccharide-based films fall short of meeting all expectations. To address this issue, the current study focused on incorporating carbon quantum dots (CQDs), which are approximately 10 nm in size, into the structure of a starch/chitosan biocomposite at varying concentrations. This modification has improved the mechanical properties of the resulting nanocomposites. The inclusion of nanoparticles led to a slight reduction in solubility and an increase in the swelling degree. The optical characteristics of the obtained films were influenced by the presence of CQDs, and the fluorescence intensity of the nanocomposites changed due to the specific heavy metal ions and amino acids used. Consequently, these nanocomposites show great potential for detecting these compounds. Cellular viability assessments and comet assays confirm that the resulting nanocomposites do not exhibit any cytotoxic properties based on this specific analytic method. The tested nanocomposites with the addition of carbon quantum dots (NC/CD II and NC/CD III) were characterised by greater genotoxicity compared to the negative control. The positive control, the starch/chitosan composite alone, was also characterised by a greater induction of chromatin damage in mouse cells compared to a pure mouse blood sample.
Steel Slag Accelerated Carbonation Curing for High-Carbonation Precast Concrete Development
Authors: Li Weilong , Wang Hui , Liu Zhichao , Li Ning , Zhao Shaowei , Hu Shuguang
Published: June 2024

Steel slag as an alkaline industrial solid waste, possesses the inherent capacity to engage in carbonation reactions with carbon dioxide (CO2). Capitalizing on this property, the current research undertakes a systematic investigation into the fabrication of high-carbonation precast concrete (HCPC). This is achieved by substituting a portion of the cementitious materials with steel slag during the carbonation curing process. The study examines the influence of varying water–binder ratios, silica fume dosages, steel slag dosages, and sand content on the compressive strength of HCPC. Findings indicate that adjusting the water–binder ratio to 0.18, adding 8% silica fume, and a sand volume ratio of 40% can significantly enhance the compressive strength of HCPC, which can reach up to 104.9 MPa. Additionally, the robust frost resistance of HCPC is substantiated by appearance damage analysis, mass loss rate, and compressive strength loss rate, after 50 freeze–thaw cycles the mass loss, and the compressive strength loss rate can meet the specification requirements. The study also corroborates the high-temperature stability of HCPC. This study optimized the preparation of HCPC and provided a feasibility for its application in precast concrete.
The Design of Decoupled Robotic Arm Based on Chain Transmission
Authors: Ma Ziling , Ding Chuan , Li Lijian , Tian Baoqiang
Published: June 2024

Unlike the conventional robotic arm where the joints are coupled to each other, this paper proposes a position and posture decoupling method to mechanically correct the end position of the robotic arm in real time through dual-motion transmission, which is both motor-reducer-driven and chain-driven; when the position of the end of the robotic arm changes, the positional linkage of each articulated arm end is unaffected. First, a single-section chain-driven decoupled robotic arm is constructed, and then the design of a two-degrees-of-freedom chain-driven decoupled robotic arm system is completed based on a single arm. Second, kinematic analysis of the decoupled robotic arm system is performed to obtain its trajectory and workspace. Moreover, an analysis of the transmission mechanism engagement clearance error is carried out. Finally, a mini-experimental prototype is built, and the rationality of the decoupled robotic arm system is proven by experiments. The experimental results show that the robotic arm is generally able to realize positional decoupling stably during movement, providing certain theoretical support and practical experience for the design requirements of related robotic arms.
Young’s Modulus and Hardness Identification of Extruded Aluminum by Scratching Damper
Authors: Wong Chun-Nam , Vyas Anand , Wong Wai-On , Sun Ruqi
Published: June 2024

A special vibration damper is proposed for Young’s modulus and hardness identification through a scratching process on extruded aluminum. This paper presents the design and working principle of a scratching damper based on a scratching device. A non-contact electromagnetic shaker is used to generate the shaking force for test sample vibration. The required forces on the scratched material during the scratching process are generated by an adjustable compression spring. The proposed damper is designed and tested on an extruded aluminum 3004 sample for the determination of its Young’s modulus and hardness, and validation is performed using the standard test instruments. The physical dimensions of the scratching tracks are measured using a microscope and utilized to compute the scratching energy factor. Load curves are obtained at different divisions of the scratching process. The loop energy during the scratching process of the tested object is measured and used for the determination of sample material properties. Furthermore, the energy conservation law, scratch energy release rate of semi-conical scratch head, and loop energy release rate are established to determine the Young’s modulus and hardness of the sample. Their estimation accuracies are evaluated. The proposed method has several advantages over the traditional methods, including low cost, directness, and high repeatability. The results suggest this to be used as an alternative to the standard modulus and hardness tester.
Source Inversion Based on Distributed Acoustic Sensing-Type Data
Authors: Shen Litao , Wang Tian-Yi , Zhang Haoran
Published: June 2024

In this study, we investigate the inverse problem of the two-dimensional wave equation source term, which arises from the Distributed Acoustic Sensing (DAS) data on the boundary. We construct a new integral operator that maps the interior sources to the DAS-type data at the boundary. Due to the noninjectivity and instability of the integral operator, which violates the well posedness of the inverse problem, a minimization problem on a compact convex subset is formulated, and the existence and uniqueness of the minimizer are obtained. Numerical examples for different cases are illustrated.
Some Results on Coefficient Estimate Problems for Four-Leaf-Type Bounded Turning Functions
Authors: Wen Chuanjun , Li Zongtao , Guo Dong
Published: June 2024

Let BT4l denote a subclass of bounded turning functions connected with a four-leaf-type domain. The goal of the study is to probe into the bounds of coefficients |b6|,|b7|,|b8|, the bounds of the logarithmic coefficients, and the third-order determinants |H3,1|,|H3,2|,|H3,3| for the functions in this class.
Improvement of Alginate Extraction from Brown Seaweed (Laminaria digitata L.) and Valorization of Its Remaining Ethanolic Fraction
Authors: Savić Gajić Ivana M. , Savić Ivan M. , Ivanovska Aleksandra M. , Vunduk Jovana D. , Mihalj Ivana S. , Svirčev Zorica B.
Published: June 2024

This study aimed to improve the conventional procedure of alginate isolation from the brown seaweed (Laminaria digitata L.) biomass and investigate the possibility of further valorization of the ethanolic fraction representing the byproduct after the degreasing and depigmentation of biomass. The acid treatment of biomass supported by ultrasound was modeled and optimized regarding the alginate yield using a response surface methodology based on the Box–Behnken design. A treatment time of 30 min, a liquid-to-solid ratio of 30 mL/g, and a treatment temperature of 47 °C were proposed as optimal conditions under which the alginate yield related to the mass of dry biomass was 30.9%. The use of ultrasonic radiation significantly reduced the time required for the acid treatment of biomass by about 4 to 24 times compared to other available conventional procedures. The isolated alginate had an M/G ratio of 1.08, which indicates a greater presence of M-blocks in its structure and the possibility of forming a soft and elastic hydrogel with its use. The chemical composition of the ethanolic fraction including total antioxidant content (293 mg gallic acid equivalent/g dry weight), total flavonoid content (14.9 mg rutin equivalent/g dry weight), contents of macroelements (the highest content of sodium, 106.59 mg/g dry weight), and microelement content (the highest content of boron, 198.84 mg/g dry weight) was determined, and the identification of bioactive compounds was carried out. The results of ultra high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry analysis confirmed the presence of 48 compounds, of which 41 compounds were identified as sugar alcohol, phenolic compounds, and lipids. According to the 2,2-diphenyl-1-picrylhydrazyl assay, the radical scavenging activity of the ethanolic fraction (the half-maximal inhibitory concentration of 42.84 ± 0.81 μg/mL) indicated its strong activity, which was almost the same as in the case of the positive control, synthetic antioxidant butylhydroxytoluene (the half-maximal inhibitory concentration of 36.61 ± 0.79 μg/mL). Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis, and Bacillus cereus) were more sensitive to the ethanolic fraction compared to Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Shigella sonnei). The obtained results indicated the possibility of the further use of the ethanolic fraction as a fertilizer for plant growth in different species and antifouling agents, applicable in aquaculture.
Harnessing Standing Sound Waves to Treat Intraocular Blood Cell Accumulation
Authors: Kenigsberg Avraham , Shperling Shany , Nagler-Avramovitz Ornit , Peleg-Levy Heli , Piperno Silvia , Skaat Alon , Leshno Ari , Shpaisman Hagay , Kapelushnik Noa
Published: June 2024

Certain ocular conditions result from the non-physiological presence of intraocular particles, leading to visual impairment and potential long-term damage. This happens when the normally clear aqueous humor becomes less transparent, thus blocking the visual axis and by intraocular pressure elevation due to blockage of the trabecular meshwork, as seen in secondary open-angle glaucoma (SOAG). Some of these “particle-related pathologies” acquire ocular conditions like pigment dispersion syndrome, pseodoexfoliation and uveitis. Others are trauma-related, such as blood cell accumulation in hyphema. While medical and surgical treatments exist for SOAG, there is a notable absence of effective preventive measures. Consequently, the prevailing clinical approach predominantly adopts a “wait and see” strategy, wherein the focus lies on managing secondary complications and offers no treatment options for particulate matter disposal. We developed a new technique utilizing standing acoustic waves to trap and direct intraocular particles. By employing acoustic trapping at nodal regions and controlled movement of the acoustic transducer, we successfully directed these particles to specific locations within the angle. Here, we demonstrate control and movement of polystyrene (PS) particles to specific locations within an in vitro eye model, as well as blood cells in porcine eyes (ex vivo). The removal of particles from certain areas can facilitate the outflow of aqueous humor (AH) and help maintain optimal intraocular pressure (IOP) levels, resulting in a non-invasive tool for preventing secondary glaucoma. Furthermore, by controlling the location of trapped particles we can hasten the clearance of the AH and improve visual acuity and quality more effectively. This study represents a significant step towards the practical application of our technique in clinical use.
Editorial for the Special Issue on Laser Additive Manufacturing: Design, Materials, Processes, and Applications, 2nd Edition
Authors: Yin Jie , Liu Yang , Ke Linda , Guan Kai
Published: June 2024

Laser-based additive manufacturing (LAM) represents one of the most forward-thinking transformations in how we conceive, design, and bring to life engineered solutions [...]
Review on Microreactors for Photo-Electrocatalysis Artificial Photosynthesis Regeneration of Coenzymes
Authors: Liu Haixia , Sun Rui , Yang Yujing , Zhang Chuanhao , Zhao Gaozhen , Zhang Kaihuan , Liang Lijuan , Huang Xiaowen
Published: June 2024

In recent years, with the outbreak of the global energy crisis, renewable solar energy has become a focal point of research. However, the utilization efficiency of natural photosynthesis (NPS) is only about 1%. Inspired by NPS, artificial photosynthesis (APS) was developed and utilized in applications such as the regeneration of coenzymes. APS for coenzyme regeneration can overcome the problem of high energy consumption in comparison to electrocatalytic methods. Microreactors represent a promising technology. Compared with the conventional system, it has the advantages of a large specific surface area, the fast diffusion of small molecules, and high efficiency. Introducing microreactors can lead to more efficient, economical, and environmentally friendly coenzyme regeneration in artificial photosynthesis. This review begins with a brief introduction of APS and microreactors, and then summarizes research on traditional electrocatalytic coenzyme regeneration, as well as photocatalytic and photo-electrocatalysis coenzyme regeneration by APS, all based on microreactors, and compares them with the corresponding conventional system. Finally, it looks forward to the promising prospects of this technology.
Empirical and Computational Evaluation of Hemolysis in a Microfluidic Extracorporeal Membrane Oxygenator Prototype
Authors: Imtiaz Nayeem , Poskus Matthew D. , Stoddard William A. , Gaborski Thomas R. , Day Steven W.
Published: June 2024

Microfluidic devices promise to overcome the limitations of conventional hemodialysis and oxygenation technologies by incorporating novel membranes with ultra-high permeability into portable devices with low blood volume. However, the characteristically small dimensions of these devices contribute to both non-physiologic shear that could damage blood components and laminar flow that inhibits transport. While many studies have been performed to empirically and computationally study hemolysis in medical devices, such as valves and blood pumps, little is known about blood damage in microfluidic devices. In this study, four variants of a representative microfluidic membrane-based oxygenator and two controls (positive and negative) are introduced, and computational models are used to predict hemolysis. The simulations were performed in ANSYS Fluent for nine shear stress-based parameter sets for the power law hemolysis model. We found that three of the nine tested parameters overpredict (5 to 10×) hemolysis compared to empirical experiments. However, three parameter sets demonstrated higher predictive accuracy for hemolysis values in devices characterized by low shear conditions, while another three parameter sets exhibited better performance for devices operating under higher shear conditions. Empirical testing of the devices in a recirculating loop revealed levels of hemolysis significantly lower (<2 ppm) than the hemolysis ranges observed in conventional oxygenators (>10 ppm). Evaluating the model’s ability to predict hemolysis across diverse shearing conditions, both through empirical experiments and computational validation, will provide valuable insights for future micro ECMO device development by directly relating geometric and shear stress with hemolysis levels. We propose that, with an informed selection of hemolysis parameters based on the shear ranges of the test device, computational modeling can complement empirical testing in the development of novel high-flow blood-contacting microfluidic devices, allowing for a more efficient iterative design process. Furthermore, the low device-induced hemolysis measured in our study at physiologically relevant flow rates is promising for the future development of microfluidic oxygenators and dialyzers.
Polarimeters for the Detection of Anisotropy from Reflectance
Authors: Kamegaki Shuji , Khajehsaeidimahabadi Zahra , Ryu Meguya , Le Nguyen Hoai An , Ng Soon Hock , Buividas Ričardas , Seniutinas Gediminas , Anand Vijayakumar , Juodkazis Saulius , Morikawa Junko
Published: June 2024

Polarimetry is used to determine the Stokes parameters of a laser beam. Once all four S0,1,2,3 parameters are determined, the state of polarisation is established. Upon reflection of a laser beam with the defined S polarisation state, the directly measured S parameters can be used to determine the optical properties of the surface, which modify the S-state upon reflection. Here, we use polarimetry for the determination of surface anisotropies related to the birefringence and dichroism of different materials, which have a common feature of linear patterns with different alignments and scales. It is shown that polarimetry in the back-reflected light is complementary to ellipsometry and four-polarisation camera imaging; experiments were carried out using a microscope.
The Mucus-Binding Factor Mediates Lacticaseibacillus rhamnosus CRL1505 Adhesion but Not Immunomodulation in the Respiratory Tract
Authors: Zhou Binghui , Elean Mariano , Arce Lorena , Fukuyama Kohtaro , Tomotsune Kae , Dentice Maidana Stefania , Saha Sudeb , Namai Fu , Nishiyama Keita , Vizoso-Pinto María Guadalupe , Villena Julio , Kitazawa Haruki
Published: June 2024

Lacticaseibacillus rhamnosus CRL1505 possesses immunomodulatory activities in the gastrointestinal and respiratory tracts when administered orally. Its adhesion to the intestinal mucosa does not condition its beneficial effects. The intranasal administration of L. rhamnosus CRL1505 is more effective than the oral route at modulating immunity in the respiratory tract. Nonetheless, it has not yet been established whether the adherence of the CRL1505 strain to the respiratory mucosa is needed to provide the immune benefits to the host. In this study, we evaluated the role of adhesion to the respiratory mucosa of the mucus-binding factor (mbf) knock-out L. rhamnosus CRL1505 mutant (Δmbf CRL1505) in the context of a Toll-like receptor 3 (TLR3)-triggered innate immunity response. In vitro adhesion studies in porcine bronchial epitheliocytes (PBE cells) indicated that L. rhamnosus Δmbf CRL1505 adhered weakly compared to the wild-type strain. However, in vivo studies in mice demonstrated that the Δmbf CRL1505 also reduced lung damage and modulated cytokine production in the respiratory tract after the activation of TLR3 to a similar extent as the wild-type strain. In addition, the mutant and the wild-type strains modulated the production of cytokines and antiviral factors by alveolar macrophages in the same way. These results suggest that the Mbf protein is partially involved in the ability of L. rhamnosus CRL1505 to adhere to the respiratory epithelium, but the protein is not necessary for the CRL1505 strain to exert its immunomodulatory beneficial effects. These findings are a step forward in the understanding of molecular interactions that mediate the beneficial effects of nasally administered probiotics.
Fried Soybean Oil Causes Systemic Low-Grade Inflammation by Disrupting the Balance of Gut Microbiota in Mice
Authors: Hu Lianhua , Huang Ling , Fang Zhijia , Wang Chen , Luo Jinjin , Deng Qi , Xu Defeng , Sun Lijun , Gooneratne Ravi
Published: June 2024

Previous reports have mainly investigated the long-term effects (>30 d), such as gut microbiota dysbiosis and systemic low-grade inflammation, in mice fed fried oil. However, short-term intake of deep-fried oil is more likely to occur in daily life, and such studies are lacking. This study aimed to investigate the short-term effects of fried oil intake on systemic low-grade inflammation. Male Kunming mice were fed non-fried soybean oil or low (25%), medium (50%), or high (100%)—fried oil at 4.4 g/kg for 6 d. Serum and fecal samples were collected on day 7. In all groups fed fried oil, the serum levels of tumor necrosis factor (TNF-α) were significantly elevated 2-4-fold. Among the gut microbiota, the abundance of Alloprevotella significantly decreased by up to 76%, while Lactobacilli significantly increased by up to 385%. The fecal valeric acid content was significantly increased and positively correlated with TNF-α levels. Both valeric acid and TNF-α levels were positively correlated with the abundance of Lactobacilli and negatively correlated with that of Alloprevotella. In summary, a short-term ingestion of even low doses of fried oil alters the gut microbiota Alloprevotella and Lactobacilli and increases fecal valeric acid content, which correlates with increased serum TNF-α levels.
Effects of Weak Electric Fields on the Denitrification Performance of Pseudomonas stutzeri: Insights into Enzymes and Metabolic Pathways
Authors: Zhu Xuyan , Lin Feng , Sun Ji , Li Xin , Zhu Guangcan , Lu Yongze , Sun Liwei , Wang Hongyang
Published: June 2024

Enhanced denitrification has been reported under weak electric fields. However, it is difficult to investigate the mechanism of enhanced denitrification due to the complex interspecific interactions of mixed-culture systems. In this study, Pseudomonas stutzeri, capable of denitrification under anaerobic conditions, was selected for treating low COD/N (2.0, ratio between concentration of chemical oxygen demand and NO3−-N) artificial wastewater under constant external voltages of 0.2, 0.4, and 0.6 V. The results revealed that P. stutzeri exhibited the highest efficiency in nitrate reduction at 0.2 V. Moreover, the maximum nitrate removal rate was 15.96 mg/(L·h) among the closed-circuit groups, 19.39% higher than that under the open-circuit group. Additionally, a notable reduction in nitrite accumulation was observed under weak electric fields. Enzyme activity analysis showed that the nitrate reductase activities were significantly increased among the closed-circuit groups, while nitrite reductase activities were inhibited. Transcriptomic analysis indicated that amino acid metabolism, carbohydrate metabolism, and energy metabolism were increased, enhancing the resistance of P. stutzeri to environmental stress and the efficiency of carbon source utilization for denitrification. The current study examined the impacts of weak electric fields on enzyme activities and microbial metabolic pathways and offers valuable insights into the mechanism by which denitrification is enhanced by weak electric fields.
The Molecular Mechanisms of Cuproptosis and Small-Molecule Drug Design in Diabetes Mellitus
Authors: Pan Zhaowen , Huang Lan , Gan Yuanyuan , Xia Yan , Yu Wei
Published: June 2024

In the field of human health research, the homeostasis of copper (Cu) is receiving increased attention due to its connection to pathological conditions, including diabetes mellitus (DM). Recent studies have demonstrated that proteins associated with Cu homeostasis, such as ATOX1, FDX1, ATP7A, ATPB, SLC31A1, p53, and UPS, also contribute to DM. Cuproptosis, characterized by Cu homeostasis dysregulation and Cu overload, has been found to cause the oligomerization of lipoylated proteins in mitochondria, loss of iron–sulfur protein, depletion of glutathione, production of reactive oxygen species, and cell death. Further research into how cuproptosis affects DM is essential to uncover its mechanism of action and identify effective interventions. In this article, we review the molecular mechanism of Cu homeostasis and the role of cuproptosis in the pathogenesis of DM. The study of small-molecule drugs that affect these proteins offers the possibility of moving from symptomatic treatment to treating the underlying causes of DM.
AgIn5S8/g-C3N4 Composite Photocatalyst Coupled with Low-Temperature Plasma-Enhanced Degradation of Hydroxypropyl-Guar-Simulated Oilfield Wastewater
Authors: Li Xiang , Zhang Yuhang , Wang Yiling , Zhu Li , Liu Yuhang , Wang Lingxing
Published: June 2024

The effective treatment and recovery of fracturing wastewater has always been one of the difficult problems to be solved in oilfield wastewater treatment. Accordingly, in this paper, photocatalytic-coupled low-temperature plasma technology was used to degrade the simulated wastewater containing hydroxypropyl guar, the main component of fracturing fluid. Results indicated that hydroxypropyl-guar wastewater could be degraded to a certain extent by either photocatalytic technology or plasma technology; the chemical oxygen demand and viscosity of the treated wastewater under two single-technique optimal conditions were 781 mg·L−1, 0.79 mPa·s−1 and 1296 mg·L−1, 1.01 mPa·s−1, respectively. Furthermore, the effective coupling of AgIn5S8/gC3N4 photocatalysis and dielectric-barrier discharge–low-temperature plasma not only enhanced the degradation degree of hydroxypropyl guar but also improved its degradation efficiency. Under the optimal conditions of coupling treatment, the hydroxypropyl-guar wastewater achieved the effect of a single treatment within 6 min, and the chemical oxygen demand and viscosity of the treated wastewater reduced to below 490 mg·L−1 and 0.65 mPa·s−1, respectively. In the process of coupled treatment, the AgIn5S8/gC3N4 could directly absorb the light and strong electric field generated by the system discharge and play an important role in the photocatalytic degradation, thus effectively improving the energy utilization rate of the discharge system and enhancing the degradation efficiency of hydroxypropyl guar.