bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN TINGKAT KEKEBALAN STRES DENGAN MEKANISME KOPING PADA LANSIA DI PANTI WREDHA SEHATI WANEA DAN PANTI WREDHA SENJA CERAH KOTA MANADO
Authors: Umanailo Novita Sarah M , Kairupan B.H. Ralph , Bidjuni Hendro J.
Published: October 2021

Abstract:  The cause of stress for elderly more often happen because they were at the nursing home while they still have a family, they feel abandoned, unneeded anymore, isolated, and lost contact with loved ones. To reduce the impact of stress they feel, the elderly should have some means to enhance stress immunity the right way. The elderly that had stress usually used coping strategy to face the problem they’d cause or feel. Objective : the purpose of this study is to find out the connection between the stress immunity level with the coping mechanism on the elderly that lived in Senja Cerah nursing home and Sehati nursing home in Manado City. The method : this study used quantitative research design with cross sectional study for the layout, it used Brieff COPE and Smith & Miller questionnaire. The study process was carried for 2 weeks and assisted by the nursing home staff for the data gathering process with use of Total Sampling technique. The total of Respondent for this study are 61 Respondents. The results of this study showed that most of the respondents had adaptive coping mechanism and immune to stress in 32 respondents (82,1%). With the result of Spearman’s rank correlation test, 0,000 < α = 0,05 was obtained and the correlation coefficient value of 0,705, meaning there is significant connection between Stress Immunity Level with the Coping Mechanism on the Elderly.Keywords: Stress Immunity, Coping Mechanism, Elderly.               Abstrak : Penyebab stres pada lansia sering kali karena ketika mereka berada di panti wredha sementara masih mempunyai keluarga, mereka merasa terbuang, tidak dibutuhkan lagi, terisolasi, dan kehilangan orang-orang yang dicintai. Untuk mengurangi dampak stres yang dirasakan, hendaknya setiap lansia mempunyai upaya-upaya peningkatan kebebalan stres yang tepat. Lansia yang mengalami stress biasanya menggunakan strategi koping untuk menghadapi masalah yang ditimbulkan atau yang dialaminya. Tujuan: tujuan dari penelitian ini adalah untuk mengetahui hubungan antara tingkat kekebalan stress dengan mekanisme koping pada lansia yang tinggal di panti wredha senja cerah dan panti wredha sehati Kota Manado.Metode: Penelitian ini menggunakan desain penelitian kuantitatif, dengan rancangan cross sectional study, menggunakan kuisioner Brieff COPE dan Smith&Miller. Proses penelitian dilakukan selama 2 minggu dan dibantu oleh pihak panti wredha untuk proses pengambilan data, dengan teknik Total Sampling. Total Responden dalam penelitian ini sebanyak 61 responden. Hasil : Hasil penelitian menunjukkan sebagian besar responden memiliki mekanisme koping adaptif dan kebal terhadap stres  sebanyak 32 responden (82,1%). Dengan hasil uji korelasi rank spearman, diperoleh sebesar 0,000 < α = 0,05 dan nilai koefisien korelasi 0,705, artinya terdapat hubungan yang signifikan antara Kekebalan Stress dengan Mekanisme Koping pada Lansia.Kata kunci : Kekebalan Stres, Mekanisme Koping, Lansia
HUBUNGAN SPOUSELESS DENGAN SELF ESTEEM PADA LANSIA DI DESA RITEY KECAMATAN AMURANGTIMUR KABUPATEN MINAHASA SELATAN
Authors: Assa Riska K , Hutauruk Minar , Natalia Adriani
Published: October 2021

Abstract : The elderly are a group of people aged 60 years and over. Advanced age is said to be the final stage of development in the human life cycle. Loss is a situation that can be experienced by individuals when there is a change in life or parting with something that previously existed.  Spouseless is one of the biggest sources of stress in the elderly. Self-esteem is a person’s evaluation of himself is positive or negative. The purpose of this study was to determine the spouseless with self esteem in the elderly in Ritey village of East Amurang district of South Minahasa regency. The research method that was used correlative study design with cross sectional study. The sample research used the purposive sampling of 36 respondents. The research instrument used the Rosenberg Self-Esteem scale. The analysis conducted was univariate analysis used frequency distribution and bivariate used Fisher’s Exact Test with SPSS program version 25.0. Conclusion the results showed Spouseless with self esteem in the elderly in Ritey village of East Amurang district of South Minahasa regency with p value = 0,019 < α =0,05.Keyword : Elderly, Spouseless, self esteem  Abstrak : Lanjut usia adalah kelompok manusia yang berusia 60 tahun keatas. Usia lanjut dikatakan sebagai tahap akhir perkembangan pada daur kehidupan manusia. Kehilangan adalah suatu situasi yang dapat dialami individu ketika adanya perubahan dalam kehidupan atau berpisah dengan sesuatu yang sebelumnya ada. Kehilangan pasangan merupakan salah satu sumber stres terbesar pada lansia. Harga diri merupakan evaluasi seseorang terhadap dirinya sendiri bersifat positif atau negatif. Tujuan penelitian ini adalah untuk mengetahui hubungan kehilangan pasangan dengan harga diri pada lansia di Desa Ritey Kecamatan Amurang Timur Kabupaten Minahasa Selatan. Metode penelitian ini menggunakan desain penelitian correlative study dengan pendekatan cross sectional study. Sampel penelitian diambil dengan cara purposive sampling sebanyak 36 responden. Alat ukur penelitian ini menggunakan kuesioner Rosenberg Self-Esteem scale. Analisa yang dilakukan adalah analisa univariat menggunakan distribusi frekuensi dan bivariat menggunakan uji Fisher’s Exact Test dengan program SPSS versi 25.0. Hasil penelitian menunjukan adanya hubungan antara kehilangan pasangan dengan harga diri pada lansia di Desa Ritey Kecamatan Amurang Timur Kabupaten Minahasa Selatan dengan nilai p value = 0,019 < α =0,05.Kata kunci : Lanjut usia, kehilangan pasangan, harga diri
Sağlıklı ve ishalli köpeklerde Genogrup I Picobirnavirusların tespiti ve moleküler karakterizasyonu
Authors: KARAYEL HACIOĞLU İlke
Published: October 2021

Picobirnaviruslar (PBV) ilk olarak 1988'de insan ve sıçanların dışkı örneklerinde tespit edilmelerinden bu yana ishalli ya da asemptomatik diğer kara ve deniz memelilerinde, kuşlarda, omurgasızlarda ve ayrıca çevresel su örneklerinde rapor edilmiştir. Buna karşın, köpeklerde, PBV tespiti ve moleküler epidemiyolojisi hakkında sadece birkaç rapor vardır. Bu çalışmada, klinik olarak ishal semptomu olan ve sağlıklı görünen 0-6 ay yaş arasındaki yavru köpeklere ait toplam 75 adet dışkı örneğinde PBV’lerin tespiti ve moleküler karakterizasyonu hedeflenmiştir. Bu amaçla örneklere, genogrup I (GGI) PBV’nin RdRp genini hedefleyen primeler kullanılarak RT-PCR uygulanmış ve test edilen örneklerin dört tanesi (%5.33) GGI PBV yönünden pozitif bulunmuştur. Bu örneklerden biri (CB1) ishalli bir köpekten, diğer üç örnek (KB19, KB29, KB30) ise klinik olarak sağlıklı görünümlü köpeklerden elde edilmiştir. Bu çalışma ülkemizde ilk defa ishalli ve klinik olarak sağlıklı görünümlü köpeklerde PBV varlığı ve moleküler karakterizasyonu ortaya konulmuştur.
Ferrous Complexes with Bis Meo in Α Substituted Tris Pyridin 2 Ylmethyl Amine Ligands Effect of the Bis Meo in Α Substituents in Dioxygen Activation and Biomimetic Reactivity
Authors:   Assistant Professor of Chemistry at Faculty of Pharmacy, Damascus, Syria., Thallaj* Dr. Nasser K
Published: October 2021

This report describes how the coordination of FeCl2 with tris(pyridin-2-ylmethyl)amine (TPA) ligands offers the possibilty to activate the molecular dioxygen in biomimetic processes. . It includes all procedures taken to the case for major oxidation reactions carried out in Nature under particular conditions. The aim of the this paper is to present the outcome of a thorough study for complex coordinations with ligands substituted by groups known as electron donors. It demonstrates how ligands with methoxy substituents are likely to be demethylated, and therefore providing entities potentially useful in synthesis. Targeting in modulating the electronic properties at the metal center, a new type of ligand (MeO)2TPA has been prepared and the complex of (MeO)2TPAFeCl2 has been studied by uv-visble ; 1H RMN paramagnatic and conductometry. The effect of (MeO) group in α-substituted on the structure as well as the effect of substitution on the oxygenation of the complex has been verified. Afterwards, the reactivity of the complex towards molecular dioxygen in absence of substrat is checked by uvvisble, 1H RMN paramagnatic and radiocristallography. As well, the reactivity in presence of substrat is tested.
The Relationship between environmental Financial accounting practices and Financial performance of industrial listed companies in Palestine Stock Exchange
Authors: Abdallah Nedal Fareed
Published: October 2021

The research aimed to investigate the applicability of environmental financial accounting practices in the industrial listed companies in Palestine Exchange and to examine the relationship between the disclosure level of environmental financial accounting practices on the company’s financial performance. The research adopted the descriptive-analytical approach, and the analysis method involved a content analysis of the annual financial reports data which were collected from Industrial listed firms on the Palestine Stock Exchange for the period from 2015 to 2019, including the firms disclosed and not disclose EFAP. Ordinary least square (OLS), fixed effect model (FEM), and random effect model (REM) were employed for processing the data. The results reveal that there is a relationship between the EFAP and financial performance. In addition, there is a difference in financial performance between the group of firms disclosed and not disclosed EFAP. Based on the findings, some recommendations are given for motivating EFAP in the listed firms for improving financial performance.
Reseña de la obra de teatro Conejo Blanco-Conejo Rojo: Innovación teatral y aportación en la industria del entretenimiento
Authors: Rodríguez Peña Brenda
Published: October 2021

Conejo Blanco-Conejo Rojo (CB-CR) es una obra de teatro escrita por Nassim Soleimanpour que surge de la historia del propio autor cuando, al no querer hacer su servicio militar por negarse a interrumpir su carrera teatral, le prohíben salir de su país, Irán, negándole el pasaporte. En consecuencia, ideó una trama ingeniosa para viajar y hacer oír su voz a través del mundo, aunque fuera sin su presencia, con lo que logró colocar su obra en varias partes del mundo, en 15 idiomas distintos. cb-cr se estrenó en 2011 en el Festival de Canadá Summerworks, sin que él pudiera presenciarla (Youngs, 2016).
SIMULATION OF THE BEHAVIOR OF A COMPUTER SYSTEM USING ARTIFICIAL NEURAL NETWORKS
Authors:   Moscow Technical University of Communication and Informatics, Sheluhin Oleg I. , Sharikov Aleksey Yu. ,   Moscow Technical University of Communication and Informatics
Published: October 2021

The design and the implementation of the simulation model of a computer system (CS) using artificial neural networks (ANNs) are considered. The purpose of the implementation is to create the easy-to-learn and easy-to-implement simulation model that allows to simulate both normal and anomalous processes in computer systems. The developed simulation model is the software, which consists of various modules combined using principles of the client-server architecture, allowing to run the model in both centralized and distributed modes of operation. The model allows to simulate the behavior of the CS with various topologies: a star, a tree, and a combination of these topologies. The main elements of the model are implemented in the form of four modules that fulfill their specific roles: an agent that generates data; a passive network element that transmits data with possible delays and losses; an active network element that processes and transmits data arriving at it, and the core – the central element of the model that receives data and sends it to additional modules for analysis. The modularity provides a high potential for further modifications of the simulation model by adding new modules. Using the generative adversarial network-based data generation module in the model makes it possible to generate data required for modeling the behavior of the studied CS. Based on the calculation of the Euclidean distance between matrices of transition probabilities of initial and generated data, it is shown that processes generated using the developed simulation model have a similar behavior with real ones. The designed model can be used to study the work of a real CS, including the imitation of an anomalous behavior.
THE CURRENT STATE AND TRENDS OF THE DEVELOPMENT OF DIGITAL TELE-RADIO BROADCASTING SYSTEMS IN THE WORLD
Authors:   Ministry of Telecommunications, Information Technology and Social Communication, Joao dos Santos Virgilio Mateus
Published: October 2021

The object of the research is to make an analysis of the current state of the digital tele-broadcasting systems in the world and the transition trends from analogue to digital systems recommended by the International Telecommunication Union (ITU-R) for use in this area are considered. Therefore, the current trend of global transition to digital tele-broadcasting is due not only to the lack of a frequency resource, but also to society’s growing demands for up-to-date information, the need to introduce common global standards and systems for broadcasting systems. expansion of digital tele-broadcasting in the context of globalization, as well as the presence of this transmission technology. In this work, he is dedicated to considering the sustainable development trends of digital satellite broadcasting in the world in the phase of migration from analog to digital technologies in this area. In the final part, the results obtained based on the research and analysis made in recommendations and in the ITU-R database are presented.
CFA BASED UNIVERSAL BIQUAD FILTER
Authors:   University of Florence, Piccirilli Maria Cristina
Published: October 2021

This paper is a review of the organizational structure and challenges that a technological enterprise faces during scaling, from the perspective of the engineering management. After expanding operations internationally, the distributed engineering teams developing hardware and software for internet of things applications, face issues regarding culture, communication, leadership, project planning and management. Relevant literature addressing these issues is presented. We elaborate on already implemented measures for improving the overall efficiency and propose further processes introduced in recent literature that can be beneficial for further optimizing the new product development. Potential knock-on effects by such implementation are also discussed. A universal biquad filter using current feedback amplifiers (CFA) as active devices and a canonical number of capacitors is presented. It realizes the classical feedforward structure through the use of grounded capacitors and MOS transistors, which permit a full integrability. The proposed circuit has attractive characteristics, as the possibility to electronically control the transfer function coefficients and the possibility to be directly inserted within cascaded configurations. The theoretical analysis of the circuit is followed by some PSPICE simulation results in agreement with the theoretical findings. In this paper a universal fully integrable biquad using CFAs as active devices and a canonical number of capacitors is presented. It realizes the classical feedforward structure [3] through the use of grounded capacitors and MOS transistors. The presence of grounded capacitors makes the proposed circuit absorb shunt parasitic capacitances. All the possible kinds of responses can be realized, while in the biquad reported in [2] only the low-pass and band-pass responses can be obtained. The numerator and denominator coefficients of the voltage transfer function of the proposed biquad can be electronically controlled by acting on the gate voltages of the MOS transistors of the circuit. Moreover the presented structure has a low-impedance output and then it can be cascaded without additional buffers.
IMPLEMENTATION OF A REDUCED COMPLEXITY HIGH PERFORMANCE DATA ACQUISITION CHIP USING 0.18 MICRON TECHNOLOGY
Authors:   Victoria University, Le Hai P. , Azyegh Aladin ,   Victoria University, Singh Jugdutt ,   Victoria University
Published: October 2021

Data acquisition (DAQ) in the general sense is the process of collecting information from the real world. For engineers and scientists, this data is mostly numerical and is usually collected, stored and analysed using computers. However, most of the input signals cannot be read directly by digital computers. Because they are generally analog signals distinguished by continuous values, while computers can only recognise digital signals containing only the on/off levels. DAQ systems are therefore inevitably necessary, as they include the translation requirements from analog signals to digital data. For this reason, they have become significant in wide range of applications in modern science and technology [1]. The paper precents the disign of a 12-bit high-speed low-power Data Acquisition (DAQ) Chip. In this paper, the disigns of the building block components are aimed at high-accuracy along with high-speed and low power dissipation. A modifided flash Analog-to-Digital converter (ADC) was used instead of the traditional flash proposed DAQ chip operates at 1 GHz master clock frequency and achieves a sampling speed of 125 MS/s. It dissipates only 64.9 mW of power as compared to 97.2 mW when traditional flash ADC was used.
EXTRACTION OF ARENES AND HETEROATOMIC COMPOUNDS FROM n-UNDECAN BY BIEXTRAGENT N-METHYLPYRROLIDONE-ETHYLENE GLYCOL
Authors:   St Petersburg State Institute of Technology (Technical University), Gaile Alexander A. , Usanova Sofia D. ,   St Petersburg State Institute of Technology (Technical University), Baranova Nadezhda S. ,   St Petersburg State Institute of Technology (Technical University)
Published: October 2021

The results of the extraction of thiophene, dibenzothiophene, diphenylamine, indole, carbazole, fluoranthene and pyrene from model mixtures with n-undecane, as well as thiophene from a mixture with n-heptane at a content of the extractable component in the binary system of 10% wt. are presented. A mixed solvent N-methylpyrrolidone - ethylene glycol with the composition of 90/10% wt. at 25 °C was used for the extraction. The experimental data obtained were compared with the results of the extraction of the same components from model mixtures with n-undecane by pure N-methylpyrrolidone
Carbon monoxide: modern concepts to the treatment of acute poisonings (literature review)
Authors: Grebenyuk Aleksandr Nikolaevich , Bykov Vladimir Nikolaevich
Published: October 2021

Introduction. Carbon monoxide (CO) is one of the most common causes of chemical injuries and the main toxic factor in the people death in fires. The mechanism of the toxic effect of CO, associated with the formation of carboxyhemoglobin and the development of hypoxia, determines the rapid development of the clinical picture of acute intoxication and the need for emergency first aid and medical care to the poisoned. Material and methods. Literature sources, summarized in the bibliographic databases eLIBRARY.RU, PubMed and Scopus, were the material for analysis. Results. First aid is based on quickly removing the victim from the fire zone or other area with a high concentration of CO and providing him with oxygen as soon as possible. During medical evacuation, it is necessary to carry out continuous inhalation of 80-100% oxygen, to ensure rest and warmth of the victim. In the emergency department of the hospital, oxygen inhalation and maintenance therapy should be continued, clinical and laboratory diagnostic measures aimed at assessing the severity of intoxication, identifying complications and concomitant pathology should be performed. In the case of severe CO poisoning, medical care continues to be provided to the victims in the intensive care unit or in the oxygen-barotherapy unit. The main antidote for CO poisoning is oxygen, which can be used in two versions - normobaric or hyperbaric oxygenation. As a pharmacological antidote to CO, zinc bisvinylimidazole diacetate (acizol) which can accelerate the breakdown of carboxyhemoglobin, improve the oxygen-binding and gas-transport properties of blood, as well as the dissociation of oxyhemoglobin in tissues is used. Along with antidotes, an important role in the treatment of CO poisoning is played by pathogenetic and symptomatic therapy aimed at the prevention and treatment of toxic encephalopathy, brain edema, cognitive dysfunction, toxic myocardiodystrophy and arrhythmia, prevention of pneumonia, correction of the acid-base state, compensation of the energy needs of the body, etc. Conclusion. Further improvement of existing means and methods for the treatment of intoxication, the development and introduction of new antidots into medical practice will increase the effectiveness of therapeutic measures, reduce the number of deaths and disabilities after acute poisoning with carbon monoxide.
Analysis of the toxicological situation in Moscow in the first three months of the COVID-19 pandemic
Authors: Simonova Anastasiya Yurevna , Rozhkov Pavel Gennadevich , Belova Mariya Vladimirovna , Ilyashenko Kapitolina Konstsntinovna , Potskhveriya Mikhail Mikhaylovich , Ostapenko Yuriy Nikolaevich , Goldfarb Yuriy Semenovich , Fetisova Anna Ivanovna , Elkov Alexandr Nikanorovich , Sokolova Tatyana Anatolevna
Published: October 2021

Introduction. On March 11, 2020, WHO announced the global COVID-19 pandemic. According to literature data, the spread of coronavirus infection COVID-19 affected the structure of acute chemical poisoning. The aim. Assessment of the impact of the COVID-19 pandemic and restrictive measures on the peculiarities of seeking advice and the structure of acute chemical poisoning in Moscow. Material and methods. The data of the registration forms “Card of recording of a consultation of a patient with acute poisoning of chemical etiology” in the period from March 30 to June 30, 2020 and 2019 were studied. The analysis indicators of a hospitalization of patients in the department of acute poisoning and somatopsychiatric disorders of N.V. Sklifosovsky, the Research Institute of Emergency Medicine. Results. It was found that in the analyzed period of 2020 compared to 2019, the proportion of injured people of working age decreased by 11.2%, while it increased at the age of 0-17 years by 3.2 times. An increase in the number of consultations for individuals by 2.1 times was noted. There was an increase in the number of complaints about poisoning with antibiotics, drugs from the T45 group (anticoagulants, vitamins, etc.), T37 (antiviral, anti-microbial, etc.) by 1.7-2 times. In March-June 2020, there was an increase in the number of complaints about the toxic effects of alcohol (T51), an increase in hospitalized patients with acute alcohol poisoning by 4 times, and with combined alcohol poisoning - by 2.7 times. The number of complaints about poisoning with detergents and disinfectants in the first three months of the pandemic increased by 2.7 times. Conclusion. The pandemic and the introduction of restrictive measures for COVID-19 have affected the toxicological situation in Moscow, which must be taken into account when determining the guidelines for organizational measures for the provision of medical care for acute chemical poisoning during the COVID-19 pandemic.
El impacto de las infraestructuras de movilidad vertical en la calidad de vida de las personas mayores: Pamplona como estudio de caso
Authors: Montoro-Gurich Carolina , Moreno-Tapia Camila
Published: October 2021

El paradigma del envejecimiento activo reivindica la atención a una creciente población longeva. A colación del mismo, el movimiento de las “ciudades amigables con los mayores” busca optimizar el uso de los espacios urbanos para mejorar la calidad de vida según se envejece. Este trabajo tiene como objetivo analizar el impacto de las infraestructuras de movilidad vertical en la calidad de vida de las personas mayores que residen en barrios con desniveles topográficos. La metodología es cualitativa y consiste en un estudio de caso de la ciudad de Pamplona (España). Los datos se han obtenido a través de entrevistas en profundidad y grupos focales. Los resultados principales son que las IMUV mejoran la accesibilidad de personas con movilidad reducida, potencian la permeabilidad urbana y, generan cambios positivos en el tejido y los usos urbanos.
Vías y entrevías: atributos y compromisos del distrito industrial de Tarragona
Authors: Zaguirre-Fernández Juan Manuel
Published: October 2021

Estudio de la forma urbana y de sus estructuras en interés por comprender lógicas fundacionales, evaluar el impacto de episodios y fenómenos urbanísticos y desvelar atributos y compromisos del distrito industrial de Tarragona, reconociendo la dualidad entre una periferia marcada por marginalidad e infraestructuras y una ciudad que se ocupa de la racionalización de su centro. Descripción y análisis de la transformación de un territorio que acometió su ocupación apoyándose en trazados que no le eran propios y que ocasionaron un intervalo de exclusión urbanística y de cómo las posibilidades urbanas arraigan entre estos conflictos. El trabajo examina la planificación urbana como reflejo de cambios sociales y tecnológicos impulsados por políticas de expansión y desarrollo que marcan este crecimiento. Concluye reconociendo el despliegue de nuevos tejidos socioeconómicos, reivindicando el proyecto urbano pendiente para esta periferia industrial.
Procesos de regeneración urbana en asentamientos humanos informales
Authors: Gómez-Villanueva Alfredo Joaquín , Rolong-Ojito Golda , Therán-Nieto Kevin Rafael
Published: October 2021

El objetivo de este artículo es analizar las estrategias de los procesos de regeneración urbana para la transformación integral y sustentable de los territorios con asentamientos humanos informales. La investigación se enfoca en entender las dinámicas sociales, urbanas y económicas, así como, las problemáticas de precariedad, exclusión y marginalidad que se originan en la consolidación de la informalidad urbana en América Latina. Los resultados definen estrategias de regeneración urbana con énfasis en el desarrollo humano sostenible de los asentamientos informales buscando el mejoramiento de la vivienda, calidad de vida, renovación del territorio, reactivación y rehabilitación paisajística.
Analysis of Factors Influencing Acupuncture Clinical Effects: A Systematic Review
Authors: Liu Yali , Jiang Honglin , LI Xiaotong , Yang Xingyue
Published: October 2021

Background Acupuncture therapy has been widely applied all around the world. But there still lacks high-quality evidence to evaluate its clinical effects, safety and cost-effectiveness, which seriously restricts its further promotion and development. Acupuncture, as an operational
intervention, is more complex than drug therapy. Factors involved in the acupuncture operation process, such as individual and interventional factors, may affect the clinical effects. Purposes Through this systematic review, we attempt to analyze the current status of studies about
the key factors influencing clinical effects, so as to provide evidence for the design of acupuncture studies. Methods A literature research was conducted in six databases until May, 2020. Studies were screened and assessed by two authors independently. Data extraction was made after
screening. We extracted the basic information of these studies, including publishing years and countries, population and factors influencing clinical effects. Results Through the initial search in these six database, 6404 records were retrieved. After duplication and screening, a total
of 355 studies were finally included in the qualitative analysis. About 88.5% of these studies were conducted in China with increasing number in the past decades, covering neurological disorders, orthopedic disorders, obstetrical and gynecological diseases, digestive diseases and so on; 239
studies focused on stimulus parameters which may influence effects, accounting for 67.3%, and 128, 44, 39, 32, 15, 11 studies discussed acupoints, patients' pathological states, individual difference, psychological states, deqi, and other factors separately. Conclusion There
are more and more studies focusing on factors influencing acupuncture clinical effects, including stimulus parameters, acupoints, individual difference, patient pathological and psychological states. Based on this systematic review, several ignored factors should be considered for future researches,
and more scientifically and objectively high quality evidence should also be proved.
Effect of Pre-admission "Quasi-collective" Education on Health Education for Patients With Ophthalmic Day Surgery
Authors: Zhang Li-Hua , Yu Rong-Yan , Ying, Ya-Fen , Yin Jing , Li Na , Cheng Yan
Published: October 2021

Objective: The present study aimed to explore the effect of pre-admission “quasi-collective” health education for patients with ophthalmic day surgery. Methods: For this study, a total of 200 patients undergoing ophthalmic day surgery from February 2019 to December 2019 were enrolled as the research subjects. The patients were divided randomly into the observation group and the control group, with 100 cases in each group. For the control group, conventional health education was conducted after admission. On the day of admission, the admission education and peri-operative health education were performed. For the observation group, pre-admission health education was provided to the patients, and detailed education on the admission instructions, pre-operative precautions, and simulation of the intra-operative process were given by the nurses. On the day of admission, the understanding of the education was evaluated, and any weaknesses in the health education were addressed. The anxiety status, method of handwashing, method of administering the drug to the eye, preoperative preparations, intra-operative training, preoperative medication, diet guidance, and postoperative care were compared between the two groups of patients. Results: Before discharge, there were significant differences in the anxiety scores, impact, and satisfaction of health education between the two groups of patients, all of which were statistically significant (P < 0.05). Conclusion: The pre-admission "quasi-collective" health education for patients undergoing day surgery in ophthalmology was better than conventional health education.
The Study of Advertisement Quality of Message, Attractiveness, and Display Frequency Influence to Purchase Intention in Indonesia
Authors: Dinar Annisa Susanti  , Yulianita
Published: October 2021

The objective of this study was to find out the effectiveness of quality of message, attractiveness, and display frequency in Dove TV advertisement in influencing the purchase intention. This study was performed with quantitative as the main approach and supported by a qualitative approach to help explain the findings. The population of this study was the Indonesia TV. The sample was drawn using purposive and quota sampling. Therefore, there were 200 female respondents between 18 to 35 years old. Meanwhile, for qualitative data gathering, there were five resources. The resources are selected randomly from 200 respondents. After quantitative analysis of the data, it is revealed that all the variables in Dove TV advertisement have a positive and significant impact on purchase intention. It means the hypothesis 1, 2, and 3 were accepted. However, the strongest impact belongs to the quality of the message. Followed by display frequencies and the last is attractiveness. Despite that, there is only a slight difference between display frequencies and attractiveness. This result is also confirmed by qualitative data analysis. Hence, the marketers should pay more attention to the quality of the message rather than any variable, without neglecting others in creating the plan for advertisement.
Mit Lernvideos gemeinsam Mathematik lernen
Authors: Schöttler Christian
Published: October 2021

In den letzten Jahren gewinnen Lernvideos sowohl im privaten Umfeld als auch im schulischen Kontext zunehmend an Bedeutung. Diesbezüglich gibt es auf verschiedenen Plattformen eine riesige Anzahl an Lernvideos zu Themen aus dem Mathematikunterricht. Allerdings sind viele dieser Videos auf eine passive Rezeption der Inhalte ausgerichtet: Mathematische Inhalte werden mithilfe von beispielhaften Aufgaben erklärt. Dabei liegt der Fokus auf einem Vormachen bzw. Vorrechnen und es werden fertige Lernprodukte präsentiert, ohne dass eine aktiv-entdeckende und kooperativ-kommunikative Auseinandersetzung mit dem Lerngegenstand ermöglicht wird. Im Artikel soll daher dargestellt werden, wie mithilfe von Lernvideos ein aktiv-entdeckendes und kooperativ-kommunikatives Lernen im Mathematikunterricht unterstützt werden kann.
Sprache im Arithmetikunterricht als Inhalt einer Blended Learning-Fortbildung
Authors: Abt Laura
Published: October 2021

Der Beitrag gibt einen Einblick in die inhaltliche Gestaltung einer Blended Learning Fortbildung zur Sprache im Arithmetikunterricht. Dazu wird anhand aktueller Befunde zur Rolle der Sprache im Mathematikunterricht die Relevanz dieses Inhalts für mathematikdidaktische Fortbildungen aufgezeigt. Ergebnisse und Hinweise aus der Forschung zur Gestaltung effektiver Fortbildungen setzen dann den Rahmen für die Umsetzung des Themas im Rahmen der Blended Learning Fortbildung. Außerdem wird gezeigt, wie bei der vorgestellten Fortbildung erhoben wurde, welche Rolle der Inhalt für die Teilnehmerinnen und Teilnehmer bei der Wahl der Fortbildung spielte und inwiefern die Inhalte praxiskompatibel waren. Zum Schluss werden erste Eindrücke aus den Erhebungen präsentiert.
Role of TRPV4 Channel in Human White Adipocytes Metabolic Activity
Authors: Sánchez Julio C. , Valencia-Vásquez Aníbal , García Andrés M.
Published: October 2021

Background: Intracellular calcium (Ca2+) homeostasis plays an essential role in adipocyte metabolism and its alteration is associated with obesity and related disorders. Transient receptor potential vanilloid 4 (TRPV4) channels are an important Ca2+ pathway in adipocytes and their activity is regulated by metabolic mediators such as insulin. In this study, we evaluated the role of TRPV4 channels in metabolic activity and adipokine secretion in human white adipocytes.Methods: Human white adipocytes were freshly cultured and the effects of the activation and inhibition of TRPV4 channels on lipolysis, glucose uptake, lactate production, and leptin and adiponectin secretion were evaluated.Results: Under basal and isoproterenol-stimulated conditions, TRPV4 activation by GSK1016709A decreased lipolysis whereas HC067047, an antagonist, increased lipolysis. The activation of TRPV4 resulted in increased glucose uptake and lactate production under both basal conditions and insulin-stimulated conditions; in contrast HC067047 decreased both parameters. Leptin production was increased, and adiponectin production was diminished by TRPV4 activation and its inhibition had the opposite effect.Conclusion: Our results suggested that TRPV4 channels are metabolic mediators involved in proadipogenic processes and glucose metabolism in adipocyte biology. TRPV4 channels could be a potential pharmacological target to treat metabolic disorders.
INIMITABLE-BASED INNOVATIVE ENTREPRENEURSHIP AS MEDIATION CONCEPTS OF INFORMATION TECHNOLOGY ROLES ON ORGANIZATIONAL PERFORMANCE
Authors: Hermawan Iwan , Suharnomo Suharnomo , Perdhana Mirwan Surya
Published: October 2021

The creative economy paradigm emphasizes the importance of ideas and intellectual property as an entrepreneurial prerequisite for being able to survive in fierce global competition. Today, an entrepreneur is required to create products with unique differences in power over competitors to stay alive in the industry. Organizational external and internal resources such as Information Technology (IT) and local culture are strategic asset sources that have an important role in building business performance. This study departs from the gap of research that is still inconclusive about the effect of IT on Organizational Performance (OP). The research direction offers novelty concepts from the perspective of resourcebased entrepreneurship theory. This paper offers the concept of Inimitable-based Innovative Entrepreneurship (IBIE),which in its ontology IBIE is the application of innovation distribution of product attributes sourced from the local nuances of design so that it becomes an iconic product that is difficult to emulate. The direction of this study will examine the concept of IBIE at the organizational level. The sample is 138 creative entrepreneurs who are SME owners who base their needs on design images that are always renewable. Hypothesis testing carried out shows empirically the IBIE variable has been able to act as a full mediation variable to bridge the gap between IT (Beta (β) = 0.747) and OP (β = 3.341). IBIE becomes a concept that fills the space of the influence of IT on OP in the body of knowledge in the entrepreneurship domain.
ANALYSIS OF THE AIRTIGHTNESS MEASUREMENT IN SINGLE OR DOUBLE APARTMENT HOUSE
Authors: Klabis Rokas , Motuzienė Violeta , Mikučionienė Rūta
Published: October 2021

The mandatory energy performance certification of new buildings or buildings for sale has been introduced in all Member States in order to achieve European Union’s energy efficiency goals. The certification of buildings sets mandatory requirements for higher energy efficiency buildings’ level of airtightness. However, a bigger problem lies in existing older residential buildings, which are energy inefficient and do not require certification. The unused potential for energy savings observed here is related to the airtightness of single and double apartment residential buildings and energy efficiency related to airtightness of them. Therefore, this work analyses the airtightness of energy class D and lower buildings based on actual airtightness measurements and evaluates the possible energy saving potential associated with the application of airtightness measures based on the example of one inefficient single apartment building. The results show that increase of the airtightness in such buildings to 3 h–1 enables to reduce the energy costs related to the airtightness in Lithuania over a period of 10 years by 0.17 TWh per year.
Triggering a Climate Change Dominated “Anthropocene”: Is It Common among Exocivilizations?
Authors: Savitch Ethan , Frank Adam , Carroll-Nellenback Jonathan , Haqq-Misra Jacob , Kleidon Axel , Alberti Marina
Published: October 2021

We seek to model the coupled evolution of a civilization and its host planet through the era when energy harvesting by the civilization drives the planet into new and adverse climate states. In this way, we ask if triggering “Anthropocenes” of the kind humanity is experiencing might be a generic feature of planet−civilization evolution. This question has direct consequences for both the study of astrobiology and the sustainability of human civilization. Furthermore, if Anthropocenes prove fatal for some civilizations then they can be considered as one form of a “Great Filter” and are therefore relevant to discussions of the Fermi Paradox. In this study, we focus on the effects of energy harvesting via combustion and vary the planet's initial chemistry and orbital radius. We find that in this context, the most influential parameter dictating a civilization's fate is their host planet’s climate sensitivity, which quantifies how global temperatures change as CO2 is added to the atmosphere. Furthermore, this is in itself a function of the planet's atmospheric CO2 level, so planets with low levels of CO2 will have high climate sensitivities and high probabilities of triggering climate change. Using simulations of the coupled nonlinear model combined with semi-analytic treatments, we find that most planets in our initial parameter space experience diminished growth due to climate effects, an event we call a “climate-dominated Anthropocene.”
Sensitivity and Specificity of Sheard and Percival’s Criteria for the Diagnosis of Young People with Near-heterophoria
Authors: Alrasheed Saif Hassan , Yousif Amel Mohamed , Moafa Majid A. , Mohamed Elmadina Abd Elaziz , Alobaid Mohammad
Published: October 2021

BACKGROUND: Sheard and Percival assumed that symptoms from latent strabismus can be avoided if the relevant fusional vergence is adequate to support the heterophoria.

AIM: The aim of the study was to determine the sensitivity and specificity of Sheard’s and Percival’s criterion for the diagnosis of heterophoria.

METHODS: A cross-sectional hospital-based study was performed at Al-Neelain Eye Hospital Khartoum, Sudan from February to October 2019. Heterophoria was measured using Maddox Wing and fusional vergence using a prism bar. Thereafter, Sheard’s and Percival’s criteria were used for the diagnosis of heterophoria.

RESULTS: A total of 230 participants (age = 15–30 years; mean age = 19.34 ± 3.325 years) were recruited for this study. The Sheard’s criteria showed a high sensitivity of 87.2% and a low specificity of 8.0% for the diagnosing of exophoria, with positive and negative predictive values of 65.5% and 26%, respectively. The criteria showed a relatively low sensitivity of 77.8% and a specificity of 9.0% in the diagnosis of esophoria, with a positive and negative predictive values of 56% and 20%, respectively. Percival criteria showed high sensitivity 84.2% and low specificity 9.1% in diagnosing esophoria, with a positive and negative predictive value of 61.5% and 25%, respectively. On the other hand, the criteria showed low sensitivity 67.4% and specificity 13.8% in diagnosing exophoria, with positive and negative predictive value 61.9% and 17%, respectively.

CONCLUSION: Sheard’s and Percival’s criteria are useful in diagnosing binocular vision problems. Sheard’s criteria are accurate in diagnosing near exophoria and Percival’s criteria are more accurate in diagnosing near esophoria. Therefore, these criteria provide good clues and predictions for the diagnosis of binocular vision problems.
Home Management of the Device Detected Atrial Fibrillation during COVID-19 Pandemic: A Case Report
Authors: Rakhimova Idaliya , Khaibullin Talgat , Smail Yerbol , Urazalina Zhanar , Koval`chuk Vitalii , Abdrakhmanov Ayan
Published: October 2021

BACKGROUND: Patients with heart failure (HF) and implanted heart devices constitute a vulnerable category during the coronavirus disease –2019 (COVID-19) pandemic. The remote monitoring function allows the physician to detect atrial fibrillation (AF) in these patients and to prevent thromboembolic complications by prescribing anticoagulants. Under quarantine conditions, such patients can receive fully remote consultation and treatment, which will protect them from the risk of infection, and also reduce the burden on medical institutions.
CASE REPORT: A 56-year-old man presented to the clinic with shortness of breath when climbing the second floor, moderate non-specific fatigue, general weakness, and a decrease in exercise tolerance. The patient received standard treatment for HF for at least 3 months (ACEI, beta blockers, MR antagonists, and loop diuretics) in individually selected adequate doses. ECG on admission showed a QRS of 150 ms, left bundle branch block (LBBB). Echo showed dilatation of all heart chambers, diffuse hypokinesis of the walls with akinesis of the apical, middle anterior LV segments, as well as hypokinesis of the basal, middle apical, and anterior septal segment of the LV. The ejection fraction was reduced to 35%. RV function is reduced. After a detailed discussion with the team, it was decided to do implantation of a cardioverter-defibrillator with resynchronization function, equipped with remote monitoring (Biotronik, and Home monitoring). Date of implantation is June 19, 2014. Due to the fact that the patient was connected to the remote monitoring system, May 5, 2020, he was diagnosed with asymptomatic AF. The episode lasted 1 min 22 s. On the following days of monitoring, episodes of AF were also recorded. The duration of the episodes ranged from a few seconds to 12 h/day. The patient received a doctor’s consultation through phone call, his risk of stroke was four when assessed using the CHA2DS2VASc scale. In treatment, it was recommended to add antiarrhythmic drugs (amiodarone 600 mg a day) and oral anticoagulants (rivaroxaban 20 mg × 1 time/day). Later, periodic IEGM showed absence of AF.
CONCLUSION: In the context of the COVID-19 pandemic, health-care providers should rethink their approach to managing patients with implanted heart devices. Modern cardiovascular implantable electronic devices allow the physician to monitor the status of patients and immediately respond to situations requiring a change in treatment. Consultations can be carried out completely online.
Identification and Analysis of Stunting Risk Factors in Children under Three Years of Age in the Area of Kampar Watershed
Authors: Yenita Riski Novera , Thamrin Thamrin , Amin Bintal , Agrina Agrina
Published: October 2021

Growth and development that is not optimal is a form of chronic malnutrition, one of which is marked by height for age which is below the standard deviation (<-2 SD) and is called stunting. Stunting has a negative impact on children's motor development, reduces children's performance in school, increases the risk of excess nutrition, infectious diseases, and even death as well as reduces productivity in adulthood. The purpose of this study was to identify risk factors for stunting in people living in the Kampar watershed. This research is a mixed-method with an explanatory sequential design which is a modification of (1–3). The research was carried out on people living in the Kampar river basin. The priority areas for specific stunting reduction interventions in this study are the Work Areas of the Kampar Kiri Hulu II Health Center, the Koto Kampar XIII Health Center, and the Kampar Kiri Health Center. This study found that the dominant factors of the five variables were home sanitation and parenting, as both affected the incidence of stunting. The findings obtained are different from the results of data analysis obtained from interviews, observations, and descriptive statistics. Based on the results of data analysis from interviews, observations, and descriptive statistics, it was found that all variables of the three factors became the main factors that had a close relationship with the incidence of stunting in the community in the Kampar watershed.
The Role of Hyperuricemia in the Pathogenesis and Progressivity of Chronic Kidney Disease
Authors: Mahadita Gede Wira , Suwitra Ketut
Published: October 2021

In humans, the end product of purine metabolism is uric acid. Over 70% of uric acid is excreted through the kidneys. When renal function is impaired, uric acid secretion is also impaired. This directly correlates the prevalence of hyperuricemia with the severity of chronic kidney disease (CKD). It has been reported that the prevalence of hyperuricemia in patients with Stage I-III CKD is 40–60% and up to 70% in patients with Stage IV-V CKD. Some studies found a link between serum uric acid levels and decreased glomerular filtration rate (GFR), an independent risk factor for CKD development. Because CKD and serum uric acid levels are related, the relationship between the two frequently generates controversy. As such, this review of the literature discusses the role of uric acid in the pathogenesis and progression of CKD.