bluuebunny/crossref_metadata_2025 huggingface dataset:
H2O2 Photosynthesis from H2O and O2 under Weak Light by Carbon Nitrides with Piezoelectric Effect
Authors: Ma Jin , Peng Cheng , Peng Xiaoxiao , Liang Sicheng , Zhou Zhixin , Wu Kaiqing , Chen Ran , Liu Songqin , Shen Yanfei , Ma Haibo , Zhang Yuanjian
Published: January 2024

Driven by the essential need of a green, safe, and low-cost approach to producing H2O2, a highly valuable multifunctional chemical, artificial photosynthesis emerges as a promising avenue. However, current catalyst systems remain challenging, due to the need of high-density sunlight, poor selectivity/activity, or/and unfavorable thermodynamics. Here, we reported that an indirect 2e- water oxidation reaction (WOR) in photocatalytic H2O2 production was unusually activated by C5N2 with piezoelectric effects. Under ultrasonication, C5N2 exhibited an overall H2O2 photosynthesis rate of 918.4 µM/h and an exceptionally high solar-to-chemical conversion efficiency of 2.6% after calibration under weak light (0.1 sun). Mechanism studies showed the piezoelectric effect of carbon nitride overcame the high uphill thermodynamics of *OH intermediate generation, which opened a new pathway for 2e- WOR, the kinetic limiting step in the overall H2O2 production from H2O and O2. Benefiting from the high efficiency of photocatalytic H2O2 production under weak light, the concept was further successfully adapted to biomedical applications in efficient sono-photo-chemodynamic therapy of tumors.
Optimizing telescoped heterogeneous catalysis with noise-resilient multi-objective Bayesian optimization
Authors: Luo Guihua , Yang Xilin , Su Weike , Qi Tingting , Xu Qilin , Su An
Published: January 2024

This study evaluates the noise resilience of multi-objective Bayesian optimization (MOBO) algorithms in chemical synthesis, an aspect critical for processes like telescoped reactions and heterogeneous catalysis but seldom systematically assessed. Through simulation experiments on amidation, acylation, and SNAr reactions under varying noise levels, we identify the qNEHVI acquisition function as notably proficient in handling noise. Subsequently, qNEHVI is employed to optimize a two-step heterogeneous catalysis for the continuous-flow synthesis of hexafluoroisopropanol. Achieving considerable optimization within just 20 experimental runs, we report an E-factor of 0.3744 and a conversion rate of 76.20%, with optimal conditions set at 5.00 sccm and 35.00℃ for the first step, and 80.00 sccm and 170℃ for the second. This research highlights qNEHVI's potential in noisy multi-objective optimization and its practical utility in refining complex synthesis processes.
Synthesis of Analogs of Waltheriones S and T and Their Activity Against Trypanosoma cruzi
Authors: Caso Carolina , Bonvin Etienne , Helbling Patrick , Berardozzi Simone , Bold Christian , Kaiser Marcel , Mäser Pascal , Altmann Karl-Heinz
Published: January 2024

Several alkaloids of the waltherione family exhibit antitrypanosomal activity in the sub-micromolar or nanomolar range. While the overwhelming majority of waltheriones are based on a quinoline core structure, two structurally simpler pyridone-based congeners, waltheriones S and T, have recently been isolated and found to inhibit Trypanosoma cruzi with single-digit micromolar potency. Here, we report on the synthesis of a series of analogs of waltheriones S and T based on pyridone ring formation via cyclization of an appropriate triketone precursor with ammonia and the assessment of their activity against Trypanosoma cruzi. The data show that the methoxy group at the C(3)-position of the pyridone ring can be removed without significant loss in potency. Further modification of 3-desmethoxy waltherione T through methoxylation at the C(1') position of the C(6)-side chain or double methoxylation at the C(1')-position and the pyridone nitrogen had no significant impact on antitrypanosomal activity. These findings contrast with the activity differences between the corresponding quinoline-based natural waltheriones M, Q, and H, where the methoxy-bearing waltheriones Q and H are one order of magnitude more potent than the unsubstituted parent compound waltherione M. Our data indicate that the SAR for monocyclic waltheriones S and T does not simply parallel that of the quinoline-based congeners and they point to the importance of a rigid quinoline core for potent activity against T. cruzi.
Regulating Reactive Oxygen Intermediates of SAzyme via Second-Shell coordination for Selective Aerobic Oxidation
Authors: Xu Yuan , Ma Yuanjie , Chen Xinghua , Wu Kaiqing , Wang Kaiyuan , Shen Yanfei , Liu Songqin , Gao Xuejiao , Zhang Yuanjian
Published: January 2024

Reactive oxygen species (ROS) regulation for artificial oxidoreductase is a key scientific issue that determines the activity, selectivity, and stability of aerobic reaction. However, the poor understanding of ROS formation mechanism greatly hampers their wider deployment. Herein, inspired by cytochromes P450 affording bound ROS intermediates in O2 activation, we report single-atom FeN4 site with tunable second-shell anion could regulate ROS generating pathways. Remarkably, the second-shell S anion coordinated FeN4 (denoted as FeNSC) delivers 2.4-fold higher oxidase-like activity and only 17% free ROS generation compared to FeNC. The detailed XANES analysis and DFT calculations reveal that the second shell S-doping significantly altered the electronic structure of FeN4 sites, leading to an increase of electron density at Fermi level and the enhanced electron transfer from active sites to the key intermediate *OOH, thereby determining the type of ROS in aerobic oxidation process. FeNC with different second-shell anion were further applied to drive aerobic oxidation reaction with enhanced activity, selectivity, and stability.
اتجاهات تطور الاستثمار الاجنبي المباشر مع نظرة خاصة لأقليم كردستان - العراق للفترة (2006-2020)
Authors: مجيد نغم , الكواز سعد , محمد امين صلاح الدين
Published: January 2024

تكمن اهمية اختيارنا لهذا الموضوع الحيوي ودراسته لتسليط الضوء على الاستثمار بغية بيان تأثير البيئة الاستثمارية بمؤشراتها  ومحدداتها وانعكاسها على تحفيز النمو الاقتصادي فالنمو اصبح قاصرا على بيئة استثمارية طاردة وان المستثمر الذي يرغب في الاستثمار يدخل في علاقة متشابكة مع البلد المضيف ويبحث دائما على البيئة الاستثمارية التي تحتل مجمل الاوضاع الاقتصادية والسياسية والقانونية والادارية والتي تضمن سلامة استثماره وتدفق عائداته . وان ابرز محددات البيئة الاستثمارية هي ( الاستقرار الامني والسياسي ، الشفافية ، النزاهة في التعاملات الادارية ، وضوح الاجراءات القانونية ، الاستقرار في سعر الصرف ومعدلات التضخم وتوفير المصارف وتطورها ، جاهزية البيئة الرقمية ، الحرية الاقتصادية ، التنمية البشرية ، واخيرا العولمة )

وان اقليم كردستان جزء من العراق يعاني من قصور في البنية التحتية على الرغم من تنفيذه للمشاريع في السنوات القليلة الماضية واعتمد على النفط كمصدر وحيدا للثروة وامتاز العراق بانه اقتصاد ريعي مما جعل الاقتصاد العراقي عرضة للتقلبات التي تحدث في اسواق النفط العالمية ،ان اهم الاستنتاجات البحث ان العراق حظي بمرتبة متأخرة  في المؤشرات الدولية لانه من الدول ذات الحرية الاقتصادية المعدومة وفي مرتبة  متقدمة في الفساد وعولمة متاخرة وكذلك تخبط بين الحكومة المركزية والهيئة الوطنية للاستثمار في خلق بيئة استثمارية مؤاتيه تحمل مقومات البيئة الناجحة .
Psilocybin-assisted psychotherapy for cancer patients
Authors: Farzin Houman
Published: January 2024

Despite significant advances in symptom management for patients affected by serious illness, physicians lack effective legal treatments for individuals suffering from demoralization, death anxiety, and existential distress. Psilocybin-assisted psychotherapy employs psilocybin-containing mushrooms or synthetic psilocybin grounded in indigenous traditions and within the context of a therapeutic mindset and environment ("set and setting") to achieve altered states of consciousness that promote healing and psychospiritual growth while reducing suffering. Current research evidence suggests that this form of therapy could serve as a safe and effective therapeutic tool for such patients.

This presentation will describe a case series of patients with advanced cancer who received physician-supervised home-based psilocybin-assisted psychotherapy in Montreal, Canada. Our experience postulates the safety and efficacy of this laborious treatment process. By executing this clinical  practice in the public healthcare system of Quebec for the first time, we have made an attempt to provide equitable access to these clinical therapies. Having performed these treatments outside the context of clinical trials, we have been able to tailor the therapeutic frame and treatment approach to a more patient-centric and culturally-informed manner. That being said, given the existing ​societal discrimination and stigma against this form of therapy, including by healthcare professionals, there remain further barriers to overcome in the equitable provision of care, especially to certain segments of the population. ​The authors will discuss these and potential solutions to addressing them.
A new communication model for procedure-oriented health care professionals
Authors: D'Arro Carmelina
Published: January 2024

Many health care communication models have been proposed, yet previous models have focused on the consultation and omit the communication needs of patients during procedures. Consider the challenges of communicating during a dental procedure, for example, in which the patient cannot talk or is experiencing anxiety or pain. How does the health care provider convey care and respect during such encounters?

A new communication model, ISLEEP, fosters patient-centered interactions for consults and procedures. There are six categories of actionable, observable behaviors in ISLEEP: introduce/interconnect, solicit, listen, empathize, explain, and affirm the power of the patient. Here, we discuss the basics of each ISLEEP skill as well as the applications of these skills for each phase of care, including consultations, immediately before procedures, during procedures, after procedures, and health counseling. Several included videos demonstrate the ISLEEP skills during live patie  nt encounters.
Facing our own dying: exploring conflicts between our individual professional stance and our own personal views on MAiD
Authors: Towers Anna
Published: January 2024

Physician-administered euthanasia (Medical-Aid-in-Dying or MAiD) has been legally available in Canada since 2016, with ever-widening indications. Most palliative care physicians in Canada do not provide MAiD themselves but will refer to colleagues who provide this procedure. The author was involved in a qualitative research project on MAiD, looking at the views of Montreal-based palliative care physicians regarding their role. One interesting finding from that project is that our own individual personal views (i.e., what I would want for myself when I will inevitably face my own death) versus my professional views as a palliative care physician (i.e., the kind of end-of-life care that I am ready to provide, or what I think patients should receive) may radically differ.

We teach our trainees (and the community beyond) that dying can have meaning up to the end of one’s natural life. Patients facing terminal illness commonly express a fear of becoming a burden to others. Yet we teach that this sentiment is often not well-founded, based on the expressed views of the patient’s loved ones. And yet dying can be difficult, even when patients receive the best available palliative care. Our professional view of what constitutes a dignified end-of-life and what patients and families (and I, eventually) will experience may be different.

This presentation will spark reflection regarding this dichotomy. What feelings might this inner split provoke, when our professional and personal views conflict with each other?  Am I being a dishonest physician? And yet…
The art and skills of compassion in practice
Authors: Sills-Maerov Margie , Valanci Sofia
Published: January 2024

Empathy, or the ability to “feel” another person’s experience, evokes strong emotions and activates the neural pathways in the pain region of the brain. Compassion is empathy combined with purposeful action to relieve suffering and impacts the brain’s reward centres.

What are the outward impacts of compassion? Compassion is human connection, reciprocity, feeling cared for and caring for another. It reduces stress and cortisol for the receiver and giver. It reduces suffering and impacts all areas of the Quadruple Aim. Yet nearly half of the population of America and 63% of providers believe that the health system is not compassionate.How do you build “compassion skills”? Being a compassionate clinician is not about knowledge, but the quality of communication and relational interactions. Many hold the belief that this ability is naturally acquired or inherent in medical practice, but this ability is technical, rooted in capabilities, intentional, and requires continuous practice and refinement. Healthcare practitioners are at a disadvantage: the rigours clinical learning and the perceived time pressures of practice take precedent, limiting the opportunity for refinement and practice of these interpersonal communication skills.

Looking to bridge the gap on continuous professional development and learning from other sectors, the Royal College of Physicians and Surgeons of Canada has been considering approaches for practice improvement in compassion. To make compassion skills tangible, the presenters offered a “coaching skills” program for physicians. Early evidence is pointing towards the positive impacts of this type of communication skills training on the therapeutic alliance.
Mindfulness and therapeutic relationships: insights from a phenomenological study of occupational therapists' practices
Authors: Smith Kirsten , Kinsella Elizabeth Anne , Moodie Sheila , McCorquodale Lisa , Teachman Gail
Published: January 2024

Background

A well-established body of literature highlights the importance of the therapeutic relationship when working with children and youth. A growing body of literature points to the potential of mindfulness to enhance the quality of relationships, including the therapeutic relationship. To date, little attention has been paid to this topic within the profession of occupational therapy.

Aim

The aim of this study was to inquire into paediatric occupational therapists’ experiences of mindfulness in the therapeutic relationship with children and youth. 

Methods

Heideggerian-informed hermeneutic phenomenology was employed as the methodological approach. Two key Heideggerian concepts of being-with and care served as theoretical underpinnings of the study. Semi-structured interviews were completed with eight North American occupational therapists to elicit their first-hand accounts of mindfulness in the therapeutic relationship with their paediatric clients. Interviews were transcribed verbatim and analyzed using a phenomenological approach.

Results

Four key themes were identified and include: fostering a safe space, enhancing presence, being authentic, and cultivating acceptance.

Conclusions

The findings offer insights regarding the potential affordances of mindfulness to support clinicians as they form of therapeutic relationships with children and youth. This study highlights research priorities for future inquiry.
ICU Bridge Program: Working with staff towards no family members feeling like "the elephant in the room"
Authors: Goin Adrian , Fox Danielle , Hornstein David
Published: January 2024

The intensive care unit (ICU) provides specialized care to critically ill patients. Given the traumatic nature of critical illness and its treatments, up to 75% of family members of ICU decedents and survivors experience long-term psychological consequences, termed post-intensive care syndrome family (PICS-F). Anxiety, PTSD, and depression are common manifestations that significantly impact families’ quality of life and the recovery of those dependent on their caregiving. Although PICS-F can be mitigated by engagement with ICU staff, critical care workers are at risk of burnout and requesting closer liaisons with families is unfeasible. Bridging visitors and the ICU health care team would ensure that family members never feel like “the elephant in the room”.The ICU Bridge Program (ICUBP) is a unique volunteering and shadowing initiative designed and run by university students. Bridge Program volunteers are assigned to hospital ICUs in Montreal to be the first point of contact for visitors. This program addresses PICS-F by humanizing the ICU experience through compassionate human contact, continuous support, and an open line of communication. The diverse applicants are carefully selected and trained to maximize soft skills, such as emotional intelligence and active listening, which ensures that families feel welcome and understood in this tense environment. Furthermore, the ICUBP’s self-sufficient structure off-loads administrative responsibilities from resource-constrained hospitals and makes its implementation feasible and cost-efficient. By continuously monitoring its effect on patients, families, and staff, the ICUBP aims to improve and expand its contribution to whole-person care in the ICU.
Reflections on teaching mindfulness to teenagers: from research to clinic
Authors: Smith Mariana , Piguet Camille , Hà-Vinh-Leuchter Russia , Merglen Arnaud
Published: January 2024

Increased stress reactivity during adolescence has been associated with vulnerability for psychiatric disorders in adulthood and mindfulness-based interventions (MBI) seem to be an option to stress. However, there is still debate on how to best teach MBI to teenagers. For the last 6 years, authors have been proposing the “Mindfulteen” (MT) to teenagers between 12 and 19 years in Geneva. The MT was first applied in different clinical trials and in a qualitative study and, as the results were encouraging, is now proposed in a clinical context at the University Hospital. Authors aim to share here some lessons learned from this experience: 1. Motivation and curiosity are key to engagement, and this is particularly important in school settings; 2. Even if adaptation is needed for different age groups, the program’s core remains easily the same; 3. Short formal practices with not much silence are needed, and metaphors can help; 4. Clarifying the intention of each practice can improve engagement, and the same explicit attitude can be brought into inquiry; 5. A trauma-sensitive approach is crucial, especially in clinical settings; 7. Proposing different versions of the same practice facilitates home practice; 8. Even if participants are not practicing between sessions, it doesn’t mean that they are not integrating mindfulness into their lives; 9. Creative and playful activities can provide rich mindful moments. In conclusion, there are open questions about teaching mindfulness to adolescents and authors believe that sharing and exchanging experiences is important to find some of the answers.
Resilience in adolescent chronic pain: an exploration of coping mechanisms and personal growth
Authors: Szwimer Rachel , Hovey Richard B.
Published: January 2024

Adolescents living with chronic pain (CP) are vulnerable to negative outcomes such as disability and impaired quality of life. They often miss opportunities for social engagement and suffer from anxiety and depression. Central to all accounts is a sense of interrupted life—phrases with negative connotations such as “couldn’t do” and “had to stop” are repeatedly used to express feelings of loss of control.

To regain control over their situation, participants create within themselves a positive internal dialogue whereby they reconstruct the meaning of normalcy, practice acceptance, make downward social comparisons, and engage in daily positive affirmations. They also create a positive external environment, surrounding themselves with compassionate individuals as well as advocating for proper accommodations at school. While CP disrupts their personal and academic trajectories, the experience of living with pain has instilled in them the pursuit of significance.

This pursuit is propelled by the imagery of a fulfilled life and seems to be particular to this age group. Ironically, some participants are grateful for their pain for granting them intuitive empathy for the suffering of others and the emotional credibility to help others.
Culturally-adapted resilience-building curriculum for medical students: a comprehensive approach at Showa University School of Medicine, Japan
Authors: Tsuchiya Shizuma , Barroga Edward , Furuta Atsuko , Arima Makiko , Ogata Hiroaki , Goto Eriko , Oshiro Tsuyoshi , Izumi Miki
Published: January 2024

The growing prevalence of psychological morbidity, depersonalization, and low personal accomplishment among medical students underscores the need for resilience-enhancing programs tailored to their specific needs. Incorporating cultural perspectives and societal context into these interventions is crucial to ensure their effectiveness and relevance. In response, Showa University School of Medicine in Japan has pioneered a culturally-adapted, resilience-based curriculum for medical students from their first through sixth years since 2020.

This presentation will outline the comprehensive framework of the resilience-focused curriculum, including course objectives, content, learning resources, timetables, and pedagogical approaches. Key components of the curriculum encompass self-assessment and reflection, stress management strategies, effective communication and conflict resolution skills, and fostering a growth mindset. Additionally, interdisciplinary collaborations with psychology and social work departments provide individual supports and resources for students.

Emphasizing the distinct challenges faced by medical students, such as academic stressors, relationships with senior clinical educators, patient and family interactions, and managing errors and burnout, the presentation will highlight the classes on the curriculum, support systems and mentorship programs in promoting mental well-being and resilience.

The experiences and outcomes of the 2020-2022 cohorts will be shared, offering valuable insights into the effectiveness of the resilience-building curriculum in the Japanese context. Lessons learned from the implementation process, including challenges faced and strategies employed, will provide practical examples for other medical schools seeking to develop similar programs.
Surrounded by text: the meaning of health represented through the texts of life. An interpretative process
Authors: Hovey Richard B.
Published: January 2024

Our omnipresent reflective worlds invite interpretation through the incalculability and types of text that surrounds us during our daily lives. We as human beings have no choice but to acknowledge this bombardment of texts as our obligatory and oblivious day-to-day engagements or be in denial of them because, as their meaning has not become relevant and interpreted within our lives.

These texts of life will continue to appear regardless of whether through an interpersonal encounter within our taken-for-granted lives, as researcher through the recounting of a research a research participant’s lived experience of something, or of a form of “art” that uniquely somehow “speaks to us”. Patients, clinicians, and researchers are offered windows, images, narratives, metaphors, or other creative expression into the complex experiences that can be explored and interpreted to help understanding complex health conditions. Chronic pain and cancer an example of these but the text associated with these transcend their medicalization to include the ontological pain associated with the day-to-day distress these can create.

This presentation offers the personal and academic reflections as a researcher and a person who lives with chronic pain and is currently undergoing a second round of chemotherapy for cancer. By finding a common ground of understanding the clinical and life experiences of living with chronic health conditions becomes mutually more accessible and may enhance the treatment of the person. The first step it to help create awareness that text and interpretation skills can benefit the clinician, the patient, and researchers.
Minds unravelling
Authors: Lefevre Kathleen
Published: January 2024

This is a poem about dealing with the traumatic aftermath of covid19. The poem is written on 4 sheets that collectively form the poster. The motifs are pressed flowers and flora with some graphing paper and blurry photographs of flowers. The colour scheme is beige and cream with bright earthy tones for the flowers. The poem is as follows:

Our minds unravelAs we peer through PPESee the quiet veilOf another historyThat couldn’t be.What do you want from me?

Pulling my cerebellumLike a cordOf chordatesOf apes.A sweater’s woven mysteryOf a loverVery unkind to me.

You speak to meFrom useless misery.You see meAs an infinite legacy.For other generationsTo take that liningAnd weaveIts silver specksWithin our identity.
Modification of hydrolyzed sweet potato starch by retrogradation to enhance
slowly digestible starch yield
Authors: Luong H.N. , Nguyen T.T.H. , Duong H.Q. , Pham T.X. , Dao T.B. , Nguyen T.N.B. , Vu T.T.
Published: January 2024

Recently, slowly digestible starch (SDS) and resistant starch (RS) have attracted the great
attention of consumers and the food industry due to their beneficial effects on human
health. The SDS ingestion resulted in a prolonged release of glucose to maintain the
glycemic index (GI) from low to moderate levels. Thus, consumption of SDS might help
fully control and prevent hyperglycemia-related diseases, such as cardiovascular disease
and diabetes. In this study, the sweet potato starch hydrolyzed by pullulanase enzyme was
continuously processed by dual-retrogradation to enhance the formation of SDS. SDS was
determined by the analytical method developed by Englyst. Results showed that in the
first retrogradation cycle, the obtained SDS content was 44.76±0.37% at 4oC after 48 h of
reaction time. The formed SDS content reached 59.72±0.97% at 4oC after 48 h of reaction
time in the second retrogradation cycle. As a result, in the whole retrogradation process,
the SDS content from sweet potato starch saw a remarkable increase from 15.04% to
59.72%.
Experiencias de internacionalización coil desarrollando proyectos de software con un enfoque ágil, A+S y ABP
Authors: Jiménez Fernández María del Consuelo , Vidal Rojas Juan Carlos
Published: January 2024

Este artículo describe el ambiente de aprendizaje, el proceso formativo y las buenas prácticas, al incorporar actividades COIL (Collaborative OnLine International Learning) en cursos universitarios relacionados a la ingeniería de software que se enfocan en aprendizaje basado en proyectos, aprendizaje servicio (A+S) y el uso de marcos de trabajo ágiles, herramientas y entornos de desarrollo profesionales para el desarrollo de proyectos de software. La experiencia considera cursos desde los primeros semestres en carreras de ingeniería, equipos de desarrollo ágil conformados por estudiantes de universidades de dos países de Latinoamérica con el propósito de generar un producto de software que aporte a solucionar necesidades de empresas, emprendedores o instituciones, siempre considerando el alineamiento con los objetivos de desarrollo sostenible. Las lecciones aprendidas de experiencias COIL previas permiten replicar las buenas prácticas COIL del desarrollo de software y enfocar el trabajo bajo el concepto de fábrica de software ágil. Los estudiantes siempre son guiados por los docentes que fungen como sus mentores, facilitando la superación de obstáculos dados por la diferencia de horarios, cultura, aprendiendo unos de otros, desarrollando diversas competencias “soft skills” como: interculturales, pensamiento crítico, colaboración, resiliencia, comunicación, creatividad, solución de conflictos, negociación y resolución de conflictos. Esta experiencia logra un aprendizaje significativo que les permite a los estudiantes salir de su zona de confort y prepararlos para la vida profesional. Finalmente, hay que mencionar que se aporta al logro de la internacionalización de la currícula y la acreditación por instancias internacionales como ABET (Accreditation Board for Engineering and Technology).
Estudio del delito de pornografía infantil en la vigente legislación paraguaya a la luz del contexto internacional en pandemia
Authors: Martínez Rodríguez Karen Luciana
Published: January 2024

El trabajo tiene como objetivo estudiar el trato de la pornografía infantil en la vigente legislación paraguaya. Se abordó en el artículo el contexto internacional de la pornografía, la protección de los niños, niñas y adolescentes en la legislación paraguaya vigente, la evolución histórica de la persecución penal de la pornografía infantil en el Paraguay, las características dogmáticas del hecho punible de pornografía infantil en el Paraguay. Se realizó una investigación con un diseño no experimental, bibliográfica, de tipo de revisión documental. Su enfoque fue jurídico descriptivo ya que la investigación tuvo como objeto la descripción de la regulación de la pornografía infantil en el derecho paraguayo. Los datos fueron recolectados de fuentes secundarias, en el ámbito nacional y en el internacional. Hubo un aumento del 300% en las denuncias realizadas por pornografía infantil ante el Ministerio Público entre los años 2020 y 2021. Es necesario controlar y regular el acceso irrestricto a internet sin supervisión de quien ejerza la patria potestad como elemento típico, a modo de controlar a los amigos virtuales y el tráfico de información compartida. La conclusión principal fue que el tipo penal está incompleto, ya que no se contempla la responsabilidad de los padres o tutores por la exposición no supervisada al internet, la cual deberá ser incluida en el tipo penal.
Pertunjukan Tarea-rea Sebagai Perwujudan Budaya Tarea-rea di Nagari Koto Gaek Guguak Kabupaten Solok Sumatera Barat
Authors: Putri Rizki Rahmadani , Syofia Ninon
Published: January 2024

Artikel ini bertujuan untuk membahas pertunjukan Tarea-rea sebagai perwujudan budaya Tarea-rea di Nagari Koto Gaek Guguak, Kabupaten Solok, Provinsi Sumatera Barat. Metode yang digunakan dalam penelitian ini adalah metode kualitatif yang bersifat deskriptif analisis. Data yang diperoleh di lapangan akan dibahas, dan data yang dianalisis sesuai dengan permasalahan yang dirumuskan.Teori yang digunakan dalam penelitian ini adalah teori budaya oleh E.B Tylor, dalam terjemahan Elly M. Setiadi, dan bentuk menurut pendapat Daryusti yang digunakan untuk membahas permasalahan dalam penelitian. Berdasarkan hasil penelitian, pertunjukan Tarea-rea atau tariang-riang merupakan sebuah kesenian tradisional yang berfungsi sebagai hiburan dan tontonan. Pertunjukan ini mencerminkan tradisi budaya Tarea-rea yang menggambarkan rasa bahagia yang berlebihan setelah panen padi, sebagai ungkapan syukur masyarakat karena mendapatkan hasil padi yang melimpah.Dalam pertunjukan Tarea-rea ini, terdapat atraksi yang menggunakan properti piring dan janjang ladiang. Biasanya, pertunjukan Tarea-rea ditampilkan sebagai hiburan dalam acara alek nagari, penyambutan tamu, dan berbagai event di Kabupaten Solok hingga saat ini.
FROM THE UNREALIZED PROJECTS OF ARCHIVAL AND ARCHAEOGRAPHIC PUBLICATIONS TO THE CURRENT STATE OF SPECIALIZED PERIODICALS IN THE REPUBLIC OF BELARUS
Authors:   Belarusian State University, Shumeiko Mikhail F.
Published: January 2024

It is noted that in the absence of any archival service in Belarus until the autumn of 1922, its functions were performed by Belarusian State University (BGU) opened in October 1921. Rector V.I. Picheta, who was at the same time the head of the department of the General Archives Administration of the RSFSR, headed the Archival Commission at the Academic Center of the People’s Commissariat of Education of the BSSR and brought forward the issue of the need for founding an archival journal in Belarus. The second time, they returned to that idea in the early 1930s, thanks to the initiative of A.R. Iodko, the head of the archival service of Belarus. However, even then the planned quarterly “Arhiu Savetskay Belarusi” was not established either. It was only in the context of the changed socio-political situation in the USSR after 1956, that the Information Bulletin of the Archival Administration of the Internal Affairs Ministry of the BSSR (the Scientific Information Bulletin of the Archival Administration attached to the BSSR Council of Ministers) started appearing. In 1961, being a small-circulation departmental publication, the Bulletin stopped being published with the 12th issue. At the end of 1991, when Belarus gained a state sovereignty, the journal “Belaruskaya Minuushchyna”, one of the founders of which was the State Archives of the Republic of Belarus, began to appear in the republic. In 1993-1998, 29 issues came out. On its basis in 1999, the journal “Arhivy i Spravavodstva” was founded with a publication frequency of once every two months. The founder of the journal is the Department of Archives and Records Management of the Ministry of Justice of the Republic of Belarus; it is published with the assistance of BelNIIDAD and BelNITsED. Significant scientific additions to the journal are the “Belaruski Arheagrafichny Shtogodnik” published since 2000 (23 issues have appeared) and the collection of scientific reports and articles “Arhivaryus” published since 2001 (20 issues have appeared). The first one is issued under the auspices of the Archaeographic Commission of the Department for Archives and Records Management, the second one is prepared by the NIAB. Since 2020, BGAMLI has been publishing the almanac “Autograph” (3 issues have been published). In conclusion, the article states that there is a significant archive-archaeographic base of periodicals and ongoing publications in the archival industry of Belarus, and they contribute to the improvement and development of archival science, archaeography, document management, as well as to the practical activities in the field of archiving and office work in the country.
“...SCIENTIFIC INSTITUTIONS ARE NOW RESUMING THEIR RELATIONS WITH THE INSTITUTIONS OF OTHER COUNTRIES”. DOCUMENTS OF THE ALL-UNION SOCIETY FOR CULTURAL RELATIONS WITH FOREIGN COUNTRIES ABOUT THE BOOK EXCHANGE IN THE 1940S OF SOVIET EGYPTOLOGISTS WITH THEIR EGYPTIAN COLLEAGUES
Authors:   Russian State University for the Humanities, Timofeeva Natalia S.
Published: January 2024

On the basis of the archival materials from the Foundation of the All-Union Society for Cultural Relations with Foreign Countries of the State Archives of the Russian Federation, the author considers the process of the book exchange in 1944–1946 between Soviet Orientalists and their Egyptian colleagues. That exchange played an important part in the Soviet-Egyptian relations, the genesis of which was interrupted with the beginning of the “Cold War”. The book transaction was carried out largely due to the activities of the Soviet Egyptologist, TASS correspondent M.A. Korostovtsev, who was sent to Egypt at the very beginning of the establishment of the diplomatic relations between the USSR and Egypt. The documents of the above Foundation cover the contacts between the Orientalists within the framework of the major institutions: the French Institute of Oriental Archeology in Cairo and the Permanent Archaeological Mission of France in Lebanon, on the one hand, and the USSR Academy of Sciences and the Institute of Oriental Studies of the USSR Academy of Sciences, on the other. As part of the shipment, the Soviet side sent the works on Iranian studies by V.V. Bartold, Arabic studies by I.Yu. Krachkovsky, the textbooks on the History of the Ancient East by B.A. Turaev and V.V. Struve, the works of the Institute of Oriental Studies of the USSR Academy of Sciences, the copies of the Journal of Ancient History for 1937–1941, as well as the five-volume edition of works by N.Ya. Marr. The article is based on the archival documents that are introduced into scientific circulation for the first time.
The Educational Objective of the Islamic Culture Course
Authors: Najar Abdelmajid , Benboudina Amar
Published: January 2024

Objectives: This study aims to shed light on the awareness-building objective of the Islamic Culture course that introduces students to the Islamic sciences they will follow classes in, allowing them to distinguish fundamental religious issues from peripheral ones in each of them. Methodology: We employed a descriptive approach to review the educational situation of Arab Muslim students, to elucidate the nature of the awareness-building element in the Islamic Culture course and to present its goals and core elements. Additionally, we used an analytical approach to analyse the aspects of Islamic educational theory operative in implementing these objectives. Results: We found that dialogical and independent learning should lie jointly at the basis of the Islamic Culture course because together they achieve the course's main objective, observing the general specifications in defining the course's content, which are inclusiveness, generality, emphasis, standardisation, and focus. Originality: This study elucidates a critical issue that still needs explanation: the cognitive framework on which the Islamic Culture course relies and its practical implementation for specialised and non-specialised students. In so doing, the study's perspective offers a fresh outlook on the course's characteristics.
The Teaching Reality of the Developed Islamic Culture Course at Qatar University in 2017-2021: A descriptive-analytical study
Authors: Benboudina Amar , Euchi Ali , Ibrahim Abubaker Mohamed Ahmed
Published: January 2024

Objectives: This study closely examines the teaching experiences regarding the Islamic Culture course at Qatar University as implemented after its development. It presents the academic community with details of this teaching experience to facilitate the exchange of knowledge regarding teaching methods for the course. Additionally, this study aims to trace how professors at the College of Sharia and Islamic Studies implemented the course development plan. Methodology: This study employs a descriptive method by describing the teaching practice surrounding the Islamic Culture course and the students' interaction with the course's practical elements. It also examines the course's multiple enhancements. Furthermore, this study involves analysis and deduction to identify indicators related to classroom planning and management. The study employs an inductive approach by randomly selecting teaching models and categorising them based on performance and similarities. Results: Identification of variations among teaching models, some aligning with the course development plan while others do not. There is no universal solution to these variations in teaching, and the unique nature of teaching the course requires adapting modern teaching methods to each particular situation, especially since the course is open to students from various backgrounds and specialities. Authenticity: Despite the richness of the experience teaching the Islamic Culture course at the College of Sharia and Islamic Studies at Qatar University, this experience still lacked adequate analysis and description. Hopefully, this study will serve as a scholarly presentation of this experience.
Safety during medical waste transport in practice
Authors:   Silesian University of Technology, Faculty of Organization & Management, Kliś Simona , Jędryczka Jakub ,   EKOMED Gospodarka Odpadami
Published: January 2024

Purpose: The aim of the article is to provide objective information about the classification of medical waste and its storage and transport based on the Silesian waste transport company – Ekomed. Generally, waste is very marginalized by society, therefore the article aims to present the further way of dealing with medical waste. Design/methodology/approach: The basic research methods were the analysis of literature on the safety of transport of medical waste, along with their categorization based on the BDO system, by example of Silesian waste transport company – EKOMED. Findings: Disposing of medical or chemical waste is a unique responsibility. Leaving such a sensitive procedure to the wrong companies or people who do not have adequate technical and personal resources may not only have dangerous consequences, but also be severely punished by applicable law. Therefore, it is worth trusting certified companies that not only have many years of experience, but also perfectly understand the responsibility of waste producers. Research limitations/implications: In the future, research will be continued in the field of medical waste transport in context of safety, especially during pandemic. Practical implications: This article provides an overview of quantitative research and diversity of medical waste from medical facilities in Poland. This review shows the importance and scale of the problem and allows for further continuation of research to manage the generated waste. The author has also noted that people generally forget about waste when they get into the bin. The main aim is to get people’s attention what is happening later with the medical waste. Originality/value: Based on empirical research, the article shows the scale of the problem that, through the new EU directives on the recycling and sustainable development, will be a forward- looking and important issue. Additionally, the article presents concepts for medical waste transport based on a Silesian company EKOMED. It’s twenty years of daily practice of transporting medical waste to the place of its disposal allowed the development of effective logistic solutions for its safe transport, which turned out to be of invaluable value during the SARS-COV-2 virus pandemic. Keywords: medical waste, transport, safety. Category of the paper: Research paper.
Pattern of coronary artery disease in Non-ST-Elevation myocardial infarction patients in diabetic and non-diabetic patients.
Authors: Muhammad Ali Khawaja  , Suleman Khan  , Zohaib Sadiq  , Amir Jameel  , Rizwan Bilal  , Omer Aslam
Published: January 2024

Objective: To compare the coronary artery disease pattern in patients with and without diabetes presenting with Non-ST-Elevation Myocardial Infarction (NSTEMI). Study Design: Retrospective, Hospital Based, Observational Comparative study. Setting: Punjab Institute of Cardiology, Lahore. Period: January 2022 to December 2022. Material & Methods: 180 Non-ST-Elevation Myocardial Infarction (NSTEMI) patients who were separated into two groups on the basis of Diabetes mellitus being absent or present and each group comprised of 90 individuals. All data was analyzed, and comparison was made among the two study groups. Results: Hypertension and smoking status was found to have significant differences among the two study groups. Significant number of individuals in the diabetic group were found to be smokers (46.6 % vs. 31.1 %; p = 0.03). The commonest risk factor in the diabetic group was noted to be hypertension. Single vessel disease was found to be significantly higher in the non-diabetic group in comparison with the diabetic group (25.5% vs 11.1%; p = 0.01) whereas diabetics showed significantly higher number of multivessel disease individuals. Coronary artery disease was more severe in the patients with Diabetes mellitus and grade was significantly higher along with LM being affected at a significantly greater rate in diabetic patients. Conclusion: Non-ST-Elevation Myocardial Infarction (NSTEMI) patients presented with Diabetes are more likely to have extensive and more severe coronary artery disease than the non-diabetic individuals.
The sofosbuvir plus ribavirin vs sofosbuvir plus daclatasvir in obtaining sustained viral response in chronic Hepatitis C.
Authors: Malik Muhammad Waseem  , Irfan Younus  , Muhammad Habib  , Adnan Qadir  , Shahid Sarwar  , Zameer Butt
Published: January 2024

Objective: To compare the Sustained viral response (SVR) in patients who had taken Sofosbuvir plus Ribavirin for 24 weeks and Sofosbuvir plus Daclatasvir for 12 weeks to treat hepatitis C. Study Design: Randomized Control Trial. Setting: Medical Division of Mayo Hospital, Lahore. Period: One Year duration, 2021. Material & Methods: 130 patients of chronic Hepatitis C were divided into two categories based on whether they met the inclusion requirements. In Group A patients used sofosbuvir plus ribavirin for six months, whereas patients of Group B took sofosbuvir plus daclatasvir for 3 months. In order to determine SVR, PCR for HCV RNA Quantitative was done at week twelve after completion of the course. SPSS 23.0 was applied to enter and analyze the data. Results: All cases had an average age of 48.80 + 16.63 years, whereas it was 48.09 +16.43 years for group A and 49.51+ 16.92 years for groups B. In group A, there were 39 cases (60%) of men and 26 cases (40%) of women, while in group B, there were 34 instances (52.3% men and 31 cases (47.7% women). SVR was attained in 34 (52.34%) of group A participants and 54 (83.12%) of group B participants (p-value of 0.001). Conclusion: Sof+Dacla group had significantly high SVR than Sof+Riba group especially in non-cirrhotic and treatment-naïve individuals.
Neural interfaces and human-computer interaction: A U.S. review: Delving into the developments, ethical considerations, and future prospects of brain-computer interfaces
Authors: Sedat Sonko  , Adefunke Fabuyide  , Kenneth Ifeanyi Ibekwe  , Emmanuel Augustine Etukudoh  , Valentine Ikenna Ilojianya
Published: January 2024

This study provides a comprehensive analysis of the developments, ethical considerations, and future prospects of brain-computer interfaces (BCIs) in the United States. The primary objective was to explore the historical evolution, current advancements, and potential societal impacts of neural interfaces in human-computer interaction. Employing a systematic literature review and content analysis methodology, the study analyzed peer-reviewed articles, government reports, and industry analyses published between 2015 and 2023. Key findings reveal significant technological advancements in neural interfaces, highlighting their transformative potential in various sectors. However, these advancements are accompanied by complex ethical dilemmas, particularly concerning privacy, security, and equitable access. The study underscores the necessity of balancing innovation with ethical considerations in the future landscape of neural interfaces. Strategic recommendations for stakeholders include fostering collaborative efforts across academia, industry, and government, developing robust regulatory frameworks, and prioritizing responsible research and development. The conclusion emphasizes the importance of ethical foresight and societal engagement in navigating the road ahead for neural interfaces in the U.S. This study contributes to the understanding of neural interfaces, providing insights into their potential benefits and challenges, and offers a framework for their ethical and sustainable development.
Strategi Pengembangan Bisnis Usaha Mikro Kecil dan Menengah (UMKM) melalui Sertifikasi Halal di Kabupaten Ponorogo
Authors: Hadi Mustofa Bagus , Luhur Prasetiyo
Published: January 2024

Label halal berdampak positif terhadap peningkatan laba yang diterima perusahaan karena tingkat kepercayaan konsumen meningkat dengan dimasukkannya produk halal pada produk. Oleh karena itu, sertifikat halal berperan penting bagi perusahaan. Selain menjaga kepercayaan konsumen, sertifikat halal juga mempengaruhi pendapatan atau omzet suatu perusahaan. Fokus penelitian penelitian ini adalah untuk melihat dan strategi pengembangan UMKM melalui sertifikasi halal di Ponorogo. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian lapangan. Pengumpulan data yang digunakan peneliti adalah wawancara, observasi dan dokumentasi. Hasil penelitian menunjukkan bahwa sertifikasi halal penting untuk memberikan perlindungan kepada konsumen dan meningkatkan pangsa pasar UMKM. Strategi yang digunakan dalam pengembangan UMKM meliputi strategi internal dan eksternal. Strategi internal terdiri dari strategi produk dan promosi. Sementara, strategi eksternal terdiri dari strategi penciptaan iklim usaha yang kondusif, perlindungan usaha, pelatihan, dan sosialisasi.